                         SEQUENCE LISTING

<110>  CureVac AG
 
<120>  RNA for wound healing

<130>  CU01P240WO1

<160>  7425  

<170>  PatentIn version 3.5

<210>  1
<211>  24
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  1

Met Ala Val Met Ala Pro Arg Thr Leu Val Leu Leu Leu Ser Gly Ala 
1               5                   10                  15      


Leu Ala Leu Thr Gln Thr Trp Ala 
            20                  


<210>  2
<211>  23
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  2

Met Asp Ala Met Lys Arg Gly Leu Cys Cys Val Leu Leu Leu Cys Gly 
1               5                   10                  15      


Ala Val Phe Val Ser Pro Ser 
            20              


<210>  3
<211>  27
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  3

Met Gly Val His Glu Cys Pro Ala Trp Leu Trp Leu Leu Leu Ser Leu 
1               5                   10                  15      


Leu Ser Leu Pro Leu Gly Leu Pro Val Leu Gly 
            20                  25          


<210>  4
<211>  18
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  4

Met Lys Trp Val Thr Phe Ile Ser Leu Leu Phe Leu Phe Ser Ser Ala 
1               5                   10                  15      


Tyr Ser 
        


<210>  5
<211>  6
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from 
       Artificial____cleavage site-Furin

<400>  5

Arg Arg Arg Arg Lys Arg 
1               5       


<210>  6
<211>  209
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  6

Met Asp Ser Asp Glu Thr Gly Phe Glu His Ser Gly Leu Trp Val Ser 
1               5                   10                  15      


Val Leu Ala Gly Leu Leu Leu Gly Ala Cys Gln Ala His Pro Ile Pro 
            20                  25                  30          


Asp Ser Ser Pro Leu Leu Gln Phe Gly Gly Gln Val Arg Gln Arg Tyr 
        35                  40                  45              


Leu Tyr Thr Asp Asp Ala Gln Gln Thr Glu Ala His Leu Glu Ile Arg 
    50                  55                  60                  


Glu Asp Gly Thr Val Gly Gly Ala Ala Asp Gln Ser Pro Glu Ser Leu 
65                  70                  75                  80  


Leu Gln Leu Lys Ala Leu Lys Pro Gly Val Ile Gln Ile Leu Gly Val 
                85                  90                  95      


Lys Thr Ser Arg Phe Leu Cys Gln Arg Pro Asp Gly Ala Leu Tyr Gly 
            100                 105                 110         


Ser Leu His Phe Asp Pro Glu Ala Cys Ser Phe Arg Glu Leu Leu Leu 
        115                 120                 125             


Glu Asp Gly Tyr Asn Val Tyr Gln Ser Glu Ala His Gly Leu Pro Leu 
    130                 135                 140                 


His Leu Pro Gly Asn Lys Ser Pro His Arg Asp Pro Ala Pro Arg Gly 
145                 150                 155                 160 


Pro Ala Arg Phe Leu Pro Leu Pro Gly Leu Pro Pro Ala Leu Pro Glu 
                165                 170                 175     


Pro Pro Gly Ile Leu Ala Pro Gln Pro Pro Asp Val Gly Ser Ser Asp 
            180                 185                 190         


Pro Leu Ser Met Val Gly Pro Ser Gln Gly Arg Ser Pro Ser Tyr Ala 
        195                 200                 205             


Ser 
    


<210>  7
<211>  469
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  7

Met His Ser Phe Pro Pro Leu Leu Leu Leu Leu Phe Trp Gly Val Val 
1               5                   10                  15      


Ser His Ser Phe Pro Ala Thr Leu Glu Thr Gln Glu Gln Asp Val Asp 
            20                  25                  30          


Leu Val Gln Lys Tyr Leu Glu Lys Tyr Tyr Asn Leu Lys Asn Asp Gly 
        35                  40                  45              


Arg Gln Val Glu Lys Arg Arg Asn Ser Gly Pro Val Val Glu Lys Leu 
    50                  55                  60                  


Lys Gln Met Gln Glu Phe Phe Gly Leu Lys Val Thr Gly Lys Pro Asp 
65                  70                  75                  80  


Ala Glu Thr Leu Lys Val Met Lys Gln Pro Arg Cys Gly Val Pro Asp 
                85                  90                  95      


Val Ala Gln Phe Val Leu Thr Glu Gly Asn Pro Arg Trp Glu Gln Thr 
            100                 105                 110         


His Leu Thr Tyr Arg Ile Glu Asn Tyr Thr Pro Asp Leu Pro Arg Ala 
        115                 120                 125             


Asp Val Asp His Ala Ile Glu Lys Ala Phe Gln Leu Trp Ser Asn Val 
    130                 135                 140                 


Thr Pro Leu Thr Phe Thr Lys Val Ser Glu Gly Gln Ala Asp Ile Met 
145                 150                 155                 160 


Ile Ser Phe Val Arg Gly Asp His Arg Asp Asn Ser Pro Phe Asp Gly 
                165                 170                 175     


Pro Gly Gly Asn Leu Ala His Ala Phe Gln Pro Gly Pro Gly Ile Gly 
            180                 185                 190         


Gly Asp Ala His Phe Asp Glu Asp Glu Arg Trp Thr Asn Asn Phe Arg 
        195                 200                 205             


Glu Tyr Asn Leu His Arg Val Ala Ala His Glu Leu Gly His Ser Leu 
    210                 215                 220                 


Gly Leu Ser His Ser Thr Asp Ile Gly Ala Leu Met Tyr Pro Ser Tyr 
225                 230                 235                 240 


Thr Phe Ser Gly Asp Val Gln Leu Ala Gln Asp Asp Ile Asp Gly Ile 
                245                 250                 255     


Gln Ala Ile Tyr Gly Arg Ser Gln Asn Pro Val Gln Pro Ile Gly Pro 
            260                 265                 270         


Gln Thr Pro Lys Ala Cys Asp Ser Lys Leu Thr Phe Asp Ala Ile Thr 
        275                 280                 285             


Thr Ile Arg Gly Glu Val Met Phe Phe Lys Asp Arg Phe Tyr Met Arg 
    290                 295                 300                 


Thr Asn Pro Phe Tyr Pro Glu Val Glu Leu Asn Phe Ile Ser Val Phe 
305                 310                 315                 320 


Trp Pro Gln Leu Pro Asn Gly Leu Glu Ala Ala Tyr Glu Phe Ala Asp 
                325                 330                 335     


Arg Asp Glu Val Arg Phe Phe Lys Gly Asn Lys Tyr Trp Ala Val Gln 
            340                 345                 350         


Gly Gln Asn Val Leu His Gly Tyr Pro Lys Asp Ile Tyr Ser Ser Phe 
        355                 360                 365             


Gly Phe Pro Arg Thr Val Lys His Ile Asp Ala Ala Leu Ser Glu Glu 
    370                 375                 380                 


Asn Thr Gly Lys Thr Tyr Phe Phe Val Ala Asn Lys Tyr Trp Arg Tyr 
385                 390                 395                 400 


Asp Glu Tyr Lys Arg Ser Met Asp Pro Gly Tyr Pro Lys Met Ile Ala 
                405                 410                 415     


His Asp Phe Pro Gly Ile Gly His Lys Val Asp Ala Val Phe Met Lys 
            420                 425                 430         


Asp Gly Phe Phe Tyr Phe Phe His Gly Thr Arg Gln Tyr Lys Phe Asp 
        435                 440                 445             


Pro Lys Thr Lys Arg Ile Leu Thr Leu Gln Lys Ala Asn Ser Trp Phe 
    450                 455                 460                 


Asn Cys Arg Lys Asn 
465                 


<210>  8
<211>  389
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  8

Met His Ser Phe Pro Pro Leu Leu Leu Leu Leu Phe Trp Gly Val Val 
1               5                   10                  15      


Ser His Ser Phe Val Leu Thr Glu Gly Asn Pro Arg Trp Glu Gln Thr 
            20                  25                  30          


His Leu Thr Tyr Arg Ile Glu Asn Tyr Thr Pro Asp Leu Pro Arg Ala 
        35                  40                  45              


Asp Val Asp His Ala Ile Glu Lys Ala Phe Gln Leu Trp Ser Asn Val 
    50                  55                  60                  


Thr Pro Leu Thr Phe Thr Lys Val Ser Glu Gly Gln Ala Asp Ile Met 
65                  70                  75                  80  


Ile Ser Phe Val Arg Gly Asp His Arg Asp Asn Ser Pro Phe Asp Gly 
                85                  90                  95      


Pro Gly Gly Asn Leu Ala His Ala Phe Gln Pro Gly Pro Gly Ile Gly 
            100                 105                 110         


Gly Asp Ala His Phe Asp Glu Asp Glu Arg Trp Thr Asn Asn Phe Arg 
        115                 120                 125             


Glu Tyr Asn Leu His Arg Val Ala Ala His Glu Leu Gly His Ser Leu 
    130                 135                 140                 


Gly Leu Ser His Ser Thr Asp Ile Gly Ala Leu Met Tyr Pro Ser Tyr 
145                 150                 155                 160 


Thr Phe Ser Gly Asp Val Gln Leu Ala Gln Asp Asp Ile Asp Gly Ile 
                165                 170                 175     


Gln Ala Ile Tyr Gly Arg Ser Gln Asn Pro Val Gln Pro Ile Gly Pro 
            180                 185                 190         


Gln Thr Pro Lys Ala Cys Asp Ser Lys Leu Thr Phe Asp Ala Ile Thr 
        195                 200                 205             


Thr Ile Arg Gly Glu Val Met Phe Phe Lys Asp Arg Phe Tyr Met Arg 
    210                 215                 220                 


Thr Asn Pro Phe Tyr Pro Glu Val Glu Leu Asn Phe Ile Ser Val Phe 
225                 230                 235                 240 


Trp Pro Gln Leu Pro Asn Gly Leu Glu Ala Ala Tyr Glu Phe Ala Asp 
                245                 250                 255     


Arg Asp Glu Val Arg Phe Phe Lys Gly Asn Lys Tyr Trp Ala Val Gln 
            260                 265                 270         


Gly Gln Asn Val Leu His Gly Tyr Pro Lys Asp Ile Tyr Ser Ser Phe 
        275                 280                 285             


Gly Phe Pro Arg Thr Val Lys His Ile Asp Ala Ala Leu Ser Glu Glu 
    290                 295                 300                 


Asn Thr Gly Lys Thr Tyr Phe Phe Val Ala Asn Lys Tyr Trp Arg Tyr 
305                 310                 315                 320 


Asp Glu Tyr Lys Arg Ser Met Asp Pro Gly Tyr Pro Lys Met Ile Ala 
                325                 330                 335     


His Asp Phe Pro Gly Ile Gly His Lys Val Asp Ala Val Phe Met Lys 
            340                 345                 350         


Asp Gly Phe Phe Tyr Phe Phe His Gly Thr Arg Gln Tyr Lys Phe Asp 
        355                 360                 365             


Pro Lys Thr Lys Arg Ile Leu Thr Leu Gln Lys Ala Asn Ser Trp Phe 
    370                 375                 380                 


Asn Cys Arg Lys Asn 
385                 


<210>  9
<211>  1118
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  9

Met Lys Lys Asn Ile Leu Lys Ile Leu Met Asp Ser Tyr Ser Lys Glu 
1               5                   10                  15      


Ser Lys Ile Gln Thr Val Arg Arg Val Thr Ser Val Ser Leu Leu Ala 
            20                  25                  30          


Val Tyr Leu Thr Met Asn Thr Ser Ser Leu Val Leu Ala Lys Pro Ile 
        35                  40                  45              


Glu Asn Thr Asn Asp Thr Ser Ile Lys Asn Val Glu Lys Leu Arg Asn 
    50                  55                  60                  


Ala Pro Asn Glu Glu Asn Ser Lys Lys Val Glu Asp Ser Lys Asn Asp 
65                  70                  75                  80  


Lys Val Glu His Val Lys Asn Ile Glu Glu Ala Lys Val Glu Gln Val 
                85                  90                  95      


Ala Pro Glu Val Lys Ser Lys Ser Thr Leu Arg Ser Ala Ser Ile Ala 
            100                 105                 110         


Asn Thr Asn Ser Glu Lys Tyr Asp Phe Glu Tyr Leu Asn Gly Leu Ser 
        115                 120                 125             


Tyr Thr Glu Leu Thr Asn Leu Ile Lys Asn Ile Lys Trp Asn Gln Ile 
    130                 135                 140                 


Asn Gly Leu Phe Asn Tyr Ser Thr Gly Ser Gln Lys Phe Phe Gly Asp 
145                 150                 155                 160 


Lys Asn Arg Val Gln Ala Ile Ile Asn Ala Leu Gln Glu Ser Gly Arg 
                165                 170                 175     


Thr Tyr Thr Ala Asn Asp Met Lys Gly Ile Glu Thr Phe Thr Glu Val 
            180                 185                 190         


Leu Arg Ala Gly Phe Tyr Leu Gly Tyr Tyr Asn Asp Gly Leu Ser Tyr 
        195                 200                 205             


Leu Asn Asp Arg Asn Phe Gln Asp Lys Cys Ile Pro Ala Met Ile Ala 
    210                 215                 220                 


Ile Gln Lys Asn Pro Asn Phe Lys Leu Gly Thr Ala Val Gln Asp Glu 
225                 230                 235                 240 


Val Ile Thr Ser Leu Gly Lys Leu Ile Gly Asn Ala Ser Ala Asn Ala 
                245                 250                 255     


Glu Val Val Asn Asn Cys Val Pro Val Leu Lys Gln Phe Arg Glu Asn 
            260                 265                 270         


Leu Asn Gln Tyr Ala Pro Asp Tyr Val Lys Gly Thr Ala Val Asn Glu 
        275                 280                 285             


Leu Ile Lys Gly Ile Glu Phe Asp Phe Ser Gly Ala Ala Tyr Glu Lys 
    290                 295                 300                 


Asp Val Lys Thr Met Pro Trp Tyr Gly Lys Ile Asp Pro Phe Ile Asn 
305                 310                 315                 320 


Glu Leu Lys Ala Leu Gly Leu Tyr Gly Asn Ile Thr Ser Ala Thr Glu 
                325                 330                 335     


Trp Ala Ser Asp Val Gly Ile Tyr Tyr Leu Ser Lys Phe Gly Leu Tyr 
            340                 345                 350         


Ser Thr Asn Arg Asn Asp Ile Val Gln Ser Leu Glu Lys Ala Val Asp 
        355                 360                 365             


Met Tyr Lys Tyr Gly Lys Ile Ala Phe Val Ala Met Glu Arg Ile Thr 
    370                 375                 380                 


Trp Asp Tyr Asp Gly Ile Gly Ser Asn Gly Lys Lys Val Asp His Asp 
385                 390                 395                 400 


Lys Phe Leu Asp Asp Ala Glu Lys His Tyr Leu Pro Lys Thr Tyr Thr 
                405                 410                 415     


Phe Asp Asn Gly Thr Phe Ile Ile Arg Ala Gly Asp Lys Val Ser Glu 
            420                 425                 430         


Glu Lys Ile Lys Arg Leu Tyr Trp Ala Ser Arg Glu Val Lys Ser Gln 
        435                 440                 445             


Phe His Arg Val Val Gly Asn Asp Lys Ala Leu Glu Val Gly Asn Ala 
    450                 455                 460                 


Asp Asp Val Leu Thr Met Lys Ile Phe Asn Ser Pro Glu Glu Tyr Lys 
465                 470                 475                 480 


Phe Asn Thr Asn Ile Asn Gly Val Ser Thr Asp Asn Gly Gly Leu Tyr 
                485                 490                 495     


Ile Glu Pro Arg Gly Thr Phe Tyr Thr Tyr Glu Arg Thr Pro Gln Gln 
            500                 505                 510         


Ser Ile Phe Ser Leu Glu Glu Leu Phe Arg His Glu Tyr Thr His Tyr 
        515                 520                 525             


Leu Gln Ala Arg Tyr Leu Val Asp Gly Leu Trp Gly Gln Gly Pro Phe 
    530                 535                 540                 


Tyr Glu Lys Asn Arg Leu Thr Trp Phe Asp Glu Gly Thr Ala Glu Phe 
545                 550                 555                 560 


Phe Ala Gly Ser Thr Arg Thr Ser Gly Val Leu Pro Arg Lys Ser Ile 
                565                 570                 575     


Leu Gly Tyr Leu Ala Lys Asp Lys Val Asp His Arg Tyr Ser Leu Lys 
            580                 585                 590         


Lys Thr Leu Asn Ser Gly Tyr Asp Asp Ser Asp Trp Met Phe Tyr Asn 
        595                 600                 605             


Tyr Gly Phe Ala Val Ala His Tyr Leu Tyr Glu Lys Asp Met Pro Thr 
    610                 615                 620                 


Phe Ile Lys Met Asn Lys Ala Ile Leu Asn Thr Asp Val Lys Ser Tyr 
625                 630                 635                 640 


Asp Glu Ile Ile Lys Lys Leu Ser Asp Asp Ala Asn Lys Asn Thr Glu 
                645                 650                 655     


Tyr Gln Asn His Ile Gln Glu Leu Ala Asp Lys Tyr Gln Gly Ala Gly 
            660                 665                 670         


Ile Pro Leu Val Ser Asp Asp Tyr Leu Lys Asp His Gly Tyr Lys Lys 
        675                 680                 685             


Ala Ser Glu Val Tyr Ser Glu Ile Ser Lys Ala Ala Ser Leu Thr Asn 
    690                 695                 700                 


Thr Ser Val Thr Ala Glu Lys Ser Gln Tyr Phe Asn Thr Phe Thr Leu 
705                 710                 715                 720 


Arg Gly Thr Tyr Thr Gly Glu Thr Ser Lys Gly Glu Phe Lys Asp Trp 
                725                 730                 735     


Asp Glu Met Ser Lys Lys Leu Asp Gly Thr Leu Glu Ser Leu Ala Lys 
            740                 745                 750         


Asn Ser Trp Ser Gly Tyr Lys Thr Leu Thr Ala Tyr Phe Thr Asn Tyr 
        755                 760                 765             


Arg Val Thr Ser Asp Asn Lys Val Gln Tyr Asp Val Val Phe His Gly 
    770                 775                 780                 


Val Leu Thr Asp Asn Ala Asp Ile Ser Asn Asn Lys Ala Pro Ile Ala 
785                 790                 795                 800 


Lys Val Thr Gly Pro Ser Thr Gly Ala Val Gly Arg Asn Ile Glu Phe 
                805                 810                 815     


Ser Gly Lys Asp Ser Lys Asp Glu Asp Gly Lys Ile Val Ser Tyr Asp 
            820                 825                 830         


Trp Asp Phe Gly Asp Gly Ala Thr Ser Arg Gly Lys Asn Ser Val His 
        835                 840                 845             


Ala Tyr Lys Lys Ala Gly Thr Tyr Asn Val Thr Leu Lys Val Thr Asp 
    850                 855                 860                 


Asp Lys Gly Ala Thr Ala Thr Glu Ser Phe Thr Ile Glu Ile Lys Asn 
865                 870                 875                 880 


Glu Asp Thr Thr Thr Pro Ile Thr Lys Glu Met Glu Pro Asn Asp Asp 
                885                 890                 895     


Ile Lys Glu Ala Asn Gly Pro Ile Val Glu Gly Val Thr Val Lys Gly 
            900                 905                 910         


Asp Leu Asn Gly Ser Asp Asp Ala Asp Thr Phe Tyr Phe Asp Val Lys 
        915                 920                 925             


Glu Asp Gly Asp Val Thr Ile Glu Leu Pro Tyr Ser Gly Ser Ser Asn 
    930                 935                 940                 


Phe Thr Trp Leu Val Tyr Lys Glu Gly Asp Asp Gln Asn His Ile Ala 
945                 950                 955                 960 


Ser Gly Ile Asp Lys Asn Asn Ser Lys Val Gly Thr Phe Lys Ser Thr 
                965                 970                 975     


Lys Gly Arg His Tyr Val Phe Ile Tyr Lys His Asp Ser Ala Ser Asn 
            980                 985                 990         


Ile Ser Tyr Ser Leu Asn Ile Lys  Gly Leu Gly Asn Glu  Lys Leu Lys 
        995                 1000                 1005             


Glu Lys  Glu Asn Asn Asp Ser  Ser Asp Lys Ala Thr  Val Ile Pro 
    1010                 1015                 1020             


Asn Phe  Asn Thr Thr Met Gln  Gly Ser Leu Leu Gly  Asp Asp Ser 
    1025                 1030                 1035             


Arg Asp  Tyr Tyr Ser Phe Glu  Val Lys Glu Glu Gly  Glu Val Asn 
    1040                 1045                 1050             


Ile Glu  Leu Asp Lys Lys Asp  Glu Phe Gly Val Thr  Trp Thr Leu 
    1055                 1060                 1065             


His Pro  Glu Ser Asn Ile Asn  Asp Arg Ile Thr Tyr  Gly Gln Val 
    1070                 1075                 1080             


Asp Gly  Asn Lys Val Ser Asn  Lys Val Lys Leu Arg  Pro Gly Lys 
    1085                 1090                 1095             


Tyr Tyr  Leu Leu Val Tyr Lys  Tyr Ser Gly Ser Gly  Asn Tyr Glu 
    1100                 1105                 1110             


Leu Arg  Val Asn Lys 
    1115             


<210>  10
<211>  1026
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  10

Met Lys Trp Val Thr Phe Ile Ser Leu Leu Phe Leu Phe Ser Ser Ala 
1               5                   10                  15      


Tyr Ser Ile Ala Asn Thr Asn Ser Glu Lys Tyr Asp Phe Glu Tyr Leu 
            20                  25                  30          


Asn Gly Leu Ser Tyr Thr Glu Leu Thr Asn Leu Ile Lys Asn Ile Lys 
        35                  40                  45              


Trp Asn Gln Ile Asn Gly Leu Phe Asn Tyr Ser Thr Gly Ser Gln Lys 
    50                  55                  60                  


Phe Phe Gly Asp Lys Asn Arg Val Gln Ala Ile Ile Asn Ala Leu Gln 
65                  70                  75                  80  


Glu Ser Gly Arg Thr Tyr Thr Ala Asn Asp Met Lys Gly Ile Glu Thr 
                85                  90                  95      


Phe Thr Glu Val Leu Arg Ala Gly Phe Tyr Leu Gly Tyr Tyr Asn Asp 
            100                 105                 110         


Gly Leu Ser Tyr Leu Asn Asp Arg Asn Phe Gln Asp Lys Cys Ile Pro 
        115                 120                 125             


Ala Met Ile Ala Ile Gln Lys Asn Pro Asn Phe Lys Leu Gly Thr Ala 
    130                 135                 140                 


Val Gln Asp Glu Val Ile Thr Ser Leu Gly Lys Leu Ile Gly Asn Ala 
145                 150                 155                 160 


Ser Ala Asn Ala Glu Val Val Asn Asn Cys Val Pro Val Leu Lys Gln 
                165                 170                 175     


Phe Arg Glu Asn Leu Asn Gln Tyr Ala Pro Asp Tyr Val Lys Gly Thr 
            180                 185                 190         


Ala Val Asn Glu Leu Ile Lys Gly Ile Glu Phe Asp Phe Ser Gly Ala 
        195                 200                 205             


Ala Tyr Glu Lys Asp Val Lys Thr Met Pro Trp Tyr Gly Lys Ile Asp 
    210                 215                 220                 


Pro Phe Ile Asn Glu Leu Lys Ala Leu Gly Leu Tyr Gly Asn Ile Thr 
225                 230                 235                 240 


Ser Ala Thr Glu Trp Ala Ser Asp Val Gly Ile Tyr Tyr Leu Ser Lys 
                245                 250                 255     


Phe Gly Leu Tyr Ser Thr Asn Arg Asn Asp Ile Val Gln Ser Leu Glu 
            260                 265                 270         


Lys Ala Val Asp Met Tyr Lys Tyr Gly Lys Ile Ala Phe Val Ala Met 
        275                 280                 285             


Glu Arg Ile Thr Trp Asp Tyr Asp Gly Ile Gly Ser Asn Gly Lys Lys 
    290                 295                 300                 


Val Asp His Asp Lys Phe Leu Asp Asp Ala Glu Lys His Tyr Leu Pro 
305                 310                 315                 320 


Lys Thr Tyr Thr Phe Asp Asn Gly Thr Phe Ile Ile Arg Ala Gly Asp 
                325                 330                 335     


Lys Val Ser Glu Glu Lys Ile Lys Arg Leu Tyr Trp Ala Ser Arg Glu 
            340                 345                 350         


Val Lys Ser Gln Phe His Arg Val Val Gly Asn Asp Lys Ala Leu Glu 
        355                 360                 365             


Val Gly Asn Ala Asp Asp Val Leu Thr Met Lys Ile Phe Asn Ser Pro 
    370                 375                 380                 


Glu Glu Tyr Lys Phe Asn Thr Asn Ile Asn Gly Val Ser Thr Asp Asn 
385                 390                 395                 400 


Gly Gly Leu Tyr Ile Glu Pro Arg Gly Thr Phe Tyr Thr Tyr Glu Arg 
                405                 410                 415     


Thr Pro Gln Gln Ser Ile Phe Ser Leu Glu Glu Leu Phe Arg His Glu 
            420                 425                 430         


Tyr Thr His Tyr Leu Gln Ala Arg Tyr Leu Val Asp Gly Leu Trp Gly 
        435                 440                 445             


Gln Gly Pro Phe Tyr Glu Lys Asn Arg Leu Thr Trp Phe Asp Glu Gly 
    450                 455                 460                 


Thr Ala Glu Phe Phe Ala Gly Ser Thr Arg Thr Ser Gly Val Leu Pro 
465                 470                 475                 480 


Arg Lys Ser Ile Leu Gly Tyr Leu Ala Lys Asp Lys Val Asp His Arg 
                485                 490                 495     


Tyr Ser Leu Lys Lys Thr Leu Asn Ser Gly Tyr Asp Asp Ser Asp Trp 
            500                 505                 510         


Met Phe Tyr Asn Tyr Gly Phe Ala Val Ala His Tyr Leu Tyr Glu Lys 
        515                 520                 525             


Asp Met Pro Thr Phe Ile Lys Met Asn Lys Ala Ile Leu Asn Thr Asp 
    530                 535                 540                 


Val Lys Ser Tyr Asp Glu Ile Ile Lys Lys Leu Ser Asp Asp Ala Asn 
545                 550                 555                 560 


Lys Asn Thr Glu Tyr Gln Asn His Ile Gln Glu Leu Ala Asp Lys Tyr 
                565                 570                 575     


Gln Gly Ala Gly Ile Pro Leu Val Ser Asp Asp Tyr Leu Lys Asp His 
            580                 585                 590         


Gly Tyr Lys Lys Ala Ser Glu Val Tyr Ser Glu Ile Ser Lys Ala Ala 
        595                 600                 605             


Ser Leu Thr Asn Thr Ser Val Thr Ala Glu Lys Ser Gln Tyr Phe Asn 
    610                 615                 620                 


Thr Phe Thr Leu Arg Gly Thr Tyr Thr Gly Glu Thr Ser Lys Gly Glu 
625                 630                 635                 640 


Phe Lys Asp Trp Asp Glu Met Ser Lys Lys Leu Asp Gly Thr Leu Glu 
                645                 650                 655     


Ser Leu Ala Lys Asn Ser Trp Ser Gly Tyr Lys Thr Leu Thr Ala Tyr 
            660                 665                 670         


Phe Thr Asn Tyr Arg Val Thr Ser Asp Asn Lys Val Gln Tyr Asp Val 
        675                 680                 685             


Val Phe His Gly Val Leu Thr Asp Asn Ala Asp Ile Ser Asn Asn Lys 
    690                 695                 700                 


Ala Pro Ile Ala Lys Val Thr Gly Pro Ser Thr Gly Ala Val Gly Arg 
705                 710                 715                 720 


Asn Ile Glu Phe Ser Gly Lys Asp Ser Lys Asp Glu Asp Gly Lys Ile 
                725                 730                 735     


Val Ser Tyr Asp Trp Asp Phe Gly Asp Gly Ala Thr Ser Arg Gly Lys 
            740                 745                 750         


Asn Ser Val His Ala Tyr Lys Lys Ala Gly Thr Tyr Asn Val Thr Leu 
        755                 760                 765             


Lys Val Thr Asp Asp Lys Gly Ala Thr Ala Thr Glu Ser Phe Thr Ile 
    770                 775                 780                 


Glu Ile Lys Asn Glu Asp Thr Thr Thr Pro Ile Thr Lys Glu Met Glu 
785                 790                 795                 800 


Pro Asn Asp Asp Ile Lys Glu Ala Asn Gly Pro Ile Val Glu Gly Val 
                805                 810                 815     


Thr Val Lys Gly Asp Leu Asn Gly Ser Asp Asp Ala Asp Thr Phe Tyr 
            820                 825                 830         


Phe Asp Val Lys Glu Asp Gly Asp Val Thr Ile Glu Leu Pro Tyr Ser 
        835                 840                 845             


Gly Ser Ser Asn Phe Thr Trp Leu Val Tyr Lys Glu Gly Asp Asp Gln 
    850                 855                 860                 


Asn His Ile Ala Ser Gly Ile Asp Lys Asn Asn Ser Lys Val Gly Thr 
865                 870                 875                 880 


Phe Lys Ser Thr Lys Gly Arg His Tyr Val Phe Ile Tyr Lys His Asp 
                885                 890                 895     


Ser Ala Ser Asn Ile Ser Tyr Ser Leu Asn Ile Lys Gly Leu Gly Asn 
            900                 905                 910         


Glu Lys Leu Lys Glu Lys Glu Asn Asn Asp Ser Ser Asp Lys Ala Thr 
        915                 920                 925             


Val Ile Pro Asn Phe Asn Thr Thr Met Gln Gly Ser Leu Leu Gly Asp 
    930                 935                 940                 


Asp Ser Arg Asp Tyr Tyr Ser Phe Glu Val Lys Glu Glu Gly Glu Val 
945                 950                 955                 960 


Asn Ile Glu Leu Asp Lys Lys Asp Glu Phe Gly Val Thr Trp Thr Leu 
                965                 970                 975     


His Pro Glu Ser Asn Ile Asn Asp Arg Ile Thr Tyr Gly Gln Val Asp 
            980                 985                 990         


Gly Asn Lys Val Ser Asn Lys Val  Lys Leu Arg Pro Gly  Lys Tyr Tyr 
        995                 1000                 1005             


Leu Leu  Val Tyr Lys Tyr Ser  Gly Ser Gly Asn Tyr  Glu Leu Arg 
    1010                 1015                 1020             


Val Asn  Lys 
    1025     


<210>  11
<211>  1142
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  11

Met Lys Trp Val Thr Phe Ile Ser Leu Leu Phe Leu Phe Ser Ser Ala 
1               5                   10                  15      


Tyr Ser Met Lys Lys Asn Ile Leu Lys Ile Leu Met Asp Ser Tyr Ser 
            20                  25                  30          


Lys Glu Ser Lys Ile Gln Thr Val Arg Arg Val Thr Ser Val Ser Leu 
        35                  40                  45              


Leu Ala Val Tyr Leu Thr Met Asn Thr Ser Ser Leu Val Leu Ala Lys 
    50                  55                  60                  


Pro Ile Glu Asn Thr Asn Asp Thr Ser Ile Lys Asn Val Glu Lys Leu 
65                  70                  75                  80  


Arg Asn Ala Pro Asn Glu Glu Asn Ser Lys Lys Val Glu Asp Ser Lys 
                85                  90                  95      


Asn Asp Lys Val Glu His Val Lys Asn Ile Glu Glu Ala Lys Val Glu 
            100                 105                 110         


Gln Val Ala Pro Glu Val Lys Ser Lys Ser Thr Leu Arg Ser Ala Ser 
        115                 120                 125             


Arg Arg Arg Arg Lys Arg Ile Ala Asn Thr Asn Ser Glu Lys Tyr Asp 
    130                 135                 140                 


Phe Glu Tyr Leu Asn Gly Leu Ser Tyr Thr Glu Leu Thr Asn Leu Ile 
145                 150                 155                 160 


Lys Asn Ile Lys Trp Asn Gln Ile Asn Gly Leu Phe Asn Tyr Ser Thr 
                165                 170                 175     


Gly Ser Gln Lys Phe Phe Gly Asp Lys Asn Arg Val Gln Ala Ile Ile 
            180                 185                 190         


Asn Ala Leu Gln Glu Ser Gly Arg Thr Tyr Thr Ala Asn Asp Met Lys 
        195                 200                 205             


Gly Ile Glu Thr Phe Thr Glu Val Leu Arg Ala Gly Phe Tyr Leu Gly 
    210                 215                 220                 


Tyr Tyr Asn Asp Gly Leu Ser Tyr Leu Asn Asp Arg Asn Phe Gln Asp 
225                 230                 235                 240 


Lys Cys Ile Pro Ala Met Ile Ala Ile Gln Lys Asn Pro Asn Phe Lys 
                245                 250                 255     


Leu Gly Thr Ala Val Gln Asp Glu Val Ile Thr Ser Leu Gly Lys Leu 
            260                 265                 270         


Ile Gly Asn Ala Ser Ala Asn Ala Glu Val Val Asn Asn Cys Val Pro 
        275                 280                 285             


Val Leu Lys Gln Phe Arg Glu Asn Leu Asn Gln Tyr Ala Pro Asp Tyr 
    290                 295                 300                 


Val Lys Gly Thr Ala Val Asn Glu Leu Ile Lys Gly Ile Glu Phe Asp 
305                 310                 315                 320 


Phe Ser Gly Ala Ala Tyr Glu Lys Asp Val Lys Thr Met Pro Trp Tyr 
                325                 330                 335     


Gly Lys Ile Asp Pro Phe Ile Asn Glu Leu Lys Ala Leu Gly Leu Tyr 
            340                 345                 350         


Gly Asn Ile Thr Ser Ala Thr Glu Trp Ala Ser Asp Val Gly Ile Tyr 
        355                 360                 365             


Tyr Leu Ser Lys Phe Gly Leu Tyr Ser Thr Asn Arg Asn Asp Ile Val 
    370                 375                 380                 


Gln Ser Leu Glu Lys Ala Val Asp Met Tyr Lys Tyr Gly Lys Ile Ala 
385                 390                 395                 400 


Phe Val Ala Met Glu Arg Ile Thr Trp Asp Tyr Asp Gly Ile Gly Ser 
                405                 410                 415     


Asn Gly Lys Lys Val Asp His Asp Lys Phe Leu Asp Asp Ala Glu Lys 
            420                 425                 430         


His Tyr Leu Pro Lys Thr Tyr Thr Phe Asp Asn Gly Thr Phe Ile Ile 
        435                 440                 445             


Arg Ala Gly Asp Lys Val Ser Glu Glu Lys Ile Lys Arg Leu Tyr Trp 
    450                 455                 460                 


Ala Ser Arg Glu Val Lys Ser Gln Phe His Arg Val Val Gly Asn Asp 
465                 470                 475                 480 


Lys Ala Leu Glu Val Gly Asn Ala Asp Asp Val Leu Thr Met Lys Ile 
                485                 490                 495     


Phe Asn Ser Pro Glu Glu Tyr Lys Phe Asn Thr Asn Ile Asn Gly Val 
            500                 505                 510         


Ser Thr Asp Asn Gly Gly Leu Tyr Ile Glu Pro Arg Gly Thr Phe Tyr 
        515                 520                 525             


Thr Tyr Glu Arg Thr Pro Gln Gln Ser Ile Phe Ser Leu Glu Glu Leu 
    530                 535                 540                 


Phe Arg His Glu Tyr Thr His Tyr Leu Gln Ala Arg Tyr Leu Val Asp 
545                 550                 555                 560 


Gly Leu Trp Gly Gln Gly Pro Phe Tyr Glu Lys Asn Arg Leu Thr Trp 
                565                 570                 575     


Phe Asp Glu Gly Thr Ala Glu Phe Phe Ala Gly Ser Thr Arg Thr Ser 
            580                 585                 590         


Gly Val Leu Pro Arg Lys Ser Ile Leu Gly Tyr Leu Ala Lys Asp Lys 
        595                 600                 605             


Val Asp His Arg Tyr Ser Leu Lys Lys Thr Leu Asn Ser Gly Tyr Asp 
    610                 615                 620                 


Asp Ser Asp Trp Met Phe Tyr Asn Tyr Gly Phe Ala Val Ala His Tyr 
625                 630                 635                 640 


Leu Tyr Glu Lys Asp Met Pro Thr Phe Ile Lys Met Asn Lys Ala Ile 
                645                 650                 655     


Leu Asn Thr Asp Val Lys Ser Tyr Asp Glu Ile Ile Lys Lys Leu Ser 
            660                 665                 670         


Asp Asp Ala Asn Lys Asn Thr Glu Tyr Gln Asn His Ile Gln Glu Leu 
        675                 680                 685             


Ala Asp Lys Tyr Gln Gly Ala Gly Ile Pro Leu Val Ser Asp Asp Tyr 
    690                 695                 700                 


Leu Lys Asp His Gly Tyr Lys Lys Ala Ser Glu Val Tyr Ser Glu Ile 
705                 710                 715                 720 


Ser Lys Ala Ala Ser Leu Thr Asn Thr Ser Val Thr Ala Glu Lys Ser 
                725                 730                 735     


Gln Tyr Phe Asn Thr Phe Thr Leu Arg Gly Thr Tyr Thr Gly Glu Thr 
            740                 745                 750         


Ser Lys Gly Glu Phe Lys Asp Trp Asp Glu Met Ser Lys Lys Leu Asp 
        755                 760                 765             


Gly Thr Leu Glu Ser Leu Ala Lys Asn Ser Trp Ser Gly Tyr Lys Thr 
    770                 775                 780                 


Leu Thr Ala Tyr Phe Thr Asn Tyr Arg Val Thr Ser Asp Asn Lys Val 
785                 790                 795                 800 


Gln Tyr Asp Val Val Phe His Gly Val Leu Thr Asp Asn Ala Asp Ile 
                805                 810                 815     


Ser Asn Asn Lys Ala Pro Ile Ala Lys Val Thr Gly Pro Ser Thr Gly 
            820                 825                 830         


Ala Val Gly Arg Asn Ile Glu Phe Ser Gly Lys Asp Ser Lys Asp Glu 
        835                 840                 845             


Asp Gly Lys Ile Val Ser Tyr Asp Trp Asp Phe Gly Asp Gly Ala Thr 
    850                 855                 860                 


Ser Arg Gly Lys Asn Ser Val His Ala Tyr Lys Lys Ala Gly Thr Tyr 
865                 870                 875                 880 


Asn Val Thr Leu Lys Val Thr Asp Asp Lys Gly Ala Thr Ala Thr Glu 
                885                 890                 895     


Ser Phe Thr Ile Glu Ile Lys Asn Glu Asp Thr Thr Thr Pro Ile Thr 
            900                 905                 910         


Lys Glu Met Glu Pro Asn Asp Asp Ile Lys Glu Ala Asn Gly Pro Ile 
        915                 920                 925             


Val Glu Gly Val Thr Val Lys Gly Asp Leu Asn Gly Ser Asp Asp Ala 
    930                 935                 940                 


Asp Thr Phe Tyr Phe Asp Val Lys Glu Asp Gly Asp Val Thr Ile Glu 
945                 950                 955                 960 


Leu Pro Tyr Ser Gly Ser Ser Asn Phe Thr Trp Leu Val Tyr Lys Glu 
                965                 970                 975     


Gly Asp Asp Gln Asn His Ile Ala Ser Gly Ile Asp Lys Asn Asn Ser 
            980                 985                 990         


Lys Val Gly Thr Phe Lys Ser Thr  Lys Gly Arg His Tyr  Val Phe Ile 
        995                 1000                 1005             


Tyr Lys  His Asp Ser Ala Ser  Asn Ile Ser Tyr Ser  Leu Asn Ile 
    1010                 1015                 1020             


Lys Gly  Leu Gly Asn Glu Lys  Leu Lys Glu Lys Glu  Asn Asn Asp 
    1025                 1030                 1035             


Ser Ser  Asp Lys Ala Thr Val  Ile Pro Asn Phe Asn  Thr Thr Met 
    1040                 1045                 1050             


Gln Gly  Ser Leu Leu Gly Asp  Asp Ser Arg Asp Tyr  Tyr Ser Phe 
    1055                 1060                 1065             


Glu Val  Lys Glu Glu Gly Glu  Val Asn Ile Glu Leu  Asp Lys Lys 
    1070                 1075                 1080             


Asp Glu  Phe Gly Val Thr Trp  Thr Leu His Pro Glu  Ser Asn Ile 
    1085                 1090                 1095             


Asn Asp  Arg Ile Thr Tyr Gly  Gln Val Asp Gly Asn  Lys Val Ser 
    1100                 1105                 1110             


Asn Lys  Val Lys Leu Arg Pro  Gly Lys Tyr Tyr Leu  Leu Val Tyr 
    1115                 1120                 1125             


Lys Tyr  Ser Gly Ser Gly Asn  Tyr Glu Leu Arg Val  Asn Lys 
    1130                 1135                 1140         


<210>  12
<211>  1034
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  12

Met Asn Phe Leu Lys Ile Ile Leu Asn Arg Gly Lys Thr Met Lys Arg 
1               5                   10                  15      


Lys Cys Leu Ser Lys Arg Leu Met Leu Ala Ile Thr Met Ala Thr Ile 
            20                  25                  30          


Phe Thr Val Asn Ser Thr Leu Pro Ile Tyr Ala Ala Val Asp Lys Asn 
        35                  40                  45              


Asn Ala Thr Ala Ala Val Gln Asn Glu Ser Lys Arg Tyr Thr Val Ser 
    50                  55                  60                  


Tyr Leu Lys Thr Leu Asn Tyr Tyr Asp Leu Val Asp Leu Leu Val Lys 
65                  70                  75                  80  


Thr Glu Ile Glu Asn Leu Pro Asp Leu Phe Gln Tyr Ser Ser Asp Ala 
                85                  90                  95      


Lys Glu Phe Tyr Gly Asn Lys Thr Arg Met Ser Phe Ile Met Asp Glu 
            100                 105                 110         


Ile Gly Arg Arg Ala Pro Gln Tyr Thr Glu Ile Asp His Lys Gly Ile 
        115                 120                 125             


Pro Thr Leu Val Glu Val Val Arg Ala Gly Phe Tyr Leu Gly Phe His 
    130                 135                 140                 


Asn Lys Glu Leu Asn Glu Ile Asn Lys Arg Ser Phe Lys Glu Arg Val 
145                 150                 155                 160 


Ile Pro Ser Ile Leu Ala Ile Gln Lys Asn Pro Asn Phe Lys Leu Gly 
                165                 170                 175     


Thr Glu Val Gln Asp Lys Ile Val Ser Ala Thr Gly Leu Leu Ala Gly 
            180                 185                 190         


Asn Glu Thr Ala Pro Pro Glu Val Val Asn Asn Phe Thr Pro Ile Leu 
        195                 200                 205             


Gln Asp Cys Ile Lys Asn Ile Asp Arg Tyr Ala Leu Asp Asp Leu Lys 
    210                 215                 220                 


Ser Lys Ala Leu Phe Asn Val Leu Ala Ala Pro Thr Tyr Asp Ile Thr 
225                 230                 235                 240 


Glu Tyr Leu Arg Ala Thr Lys Glu Lys Pro Glu Asn Thr Pro Trp Tyr 
                245                 250                 255     


Gly Lys Ile Asp Gly Phe Ile Asn Glu Leu Lys Lys Leu Ala Leu Tyr 
            260                 265                 270         


Gly Lys Ile Asn Asp Asn Asn Ser Trp Ile Ile Asp Asn Gly Ile Tyr 
        275                 280                 285             


His Ile Ala Pro Leu Gly Lys Leu His Ser Asn Asn Lys Ile Gly Ile 
    290                 295                 300                 


Glu Thr Leu Thr Glu Val Met Lys Val Tyr Pro Tyr Leu Ser Met Gln 
305                 310                 315                 320 


His Leu Gln Ser Ala Asp Gln Ile Lys Arg His Tyr Asp Ser Lys Asp 
                325                 330                 335     


Ala Glu Gly Asn Lys Ile Pro Leu Asp Lys Phe Lys Lys Glu Gly Lys 
            340                 345                 350         


Glu Lys Tyr Cys Pro Lys Thr Tyr Thr Phe Asp Asp Gly Lys Val Ile 
        355                 360                 365             


Ile Lys Ala Gly Ala Arg Val Glu Glu Glu Lys Val Lys Arg Leu Tyr 
    370                 375                 380                 


Trp Ala Ser Lys Glu Val Asn Ser Gln Phe Phe Arg Val Tyr Gly Ile 
385                 390                 395                 400 


Asp Lys Pro Leu Glu Glu Gly Asn Pro Asp Asp Ile Leu Thr Met Val 
                405                 410                 415     


Ile Tyr Asn Ser Pro Glu Glu Tyr Lys Leu Asn Ser Val Leu Tyr Gly 
            420                 425                 430         


Tyr Asp Thr Asn Asn Gly Gly Met Tyr Ile Glu Pro Glu Gly Thr Phe 
        435                 440                 445             


Phe Thr Tyr Glu Arg Glu Ala Gln Glu Ser Thr Tyr Thr Leu Glu Glu 
    450                 455                 460                 


Leu Phe Arg His Glu Tyr Thr His Tyr Leu Gln Gly Arg Tyr Ala Val 
465                 470                 475                 480 


Pro Gly Gln Trp Gly Arg Thr Lys Leu Tyr Asp Asn Asp Arg Leu Thr 
                485                 490                 495     


Trp Tyr Glu Glu Gly Gly Ala Glu Leu Phe Ala Gly Ser Thr Arg Thr 
            500                 505                 510         


Ser Gly Ile Leu Pro Arg Lys Ser Ile Val Ser Asn Ile His Asn Thr 
        515                 520                 525             


Thr Arg Asn Asn Arg Tyr Lys Leu Ser Asp Thr Val His Ser Lys Tyr 
    530                 535                 540                 


Gly Ala Ser Phe Glu Phe Tyr Asn Tyr Ala Cys Met Phe Met Asp Tyr 
545                 550                 555                 560 


Met Tyr Asn Lys Asp Met Gly Ile Leu Asn Lys Leu Asn Asp Leu Ala 
                565                 570                 575     


Lys Asn Asn Asp Val Asp Gly Tyr Asp Asn Tyr Ile Arg Asp Leu Ser 
            580                 585                 590         


Ser Asn Tyr Ala Leu Asn Asp Lys Tyr Gln Asp His Met Gln Glu Arg 
        595                 600                 605             


Ile Asp Asn Tyr Glu Asn Leu Thr Val Pro Phe Val Ala Asp Asp Tyr 
    610                 615                 620                 


Leu Val Arg His Ala Tyr Lys Asn Pro Asn Glu Ile Tyr Ser Glu Ile 
625                 630                 635                 640 


Ser Glu Val Ala Lys Leu Lys Asp Ala Lys Ser Glu Val Lys Lys Ser 
                645                 650                 655     


Gln Tyr Phe Ser Thr Phe Thr Leu Arg Gly Ser Tyr Thr Gly Gly Ala 
            660                 665                 670         


Ser Lys Gly Lys Leu Glu Asp Gln Lys Ala Met Asn Lys Phe Ile Asp 
        675                 680                 685             


Asp Ser Leu Lys Lys Leu Asp Thr Tyr Ser Trp Ser Gly Tyr Lys Thr 
    690                 695                 700                 


Leu Thr Ala Tyr Phe Thr Asn Tyr Lys Val Asp Ser Ser Asn Arg Val 
705                 710                 715                 720 


Thr Tyr Asp Val Val Phe His Gly Tyr Leu Pro Asn Glu Gly Asp Ser 
                725                 730                 735     


Lys Asn Ser Leu Pro Tyr Gly Lys Ile Asn Gly Thr Tyr Lys Gly Thr 
            740                 745                 750         


Glu Lys Glu Lys Ile Lys Phe Ser Ser Glu Gly Ser Phe Asp Pro Asp 
        755                 760                 765             


Gly Lys Ile Val Ser Tyr Glu Trp Asp Phe Gly Asp Gly Asn Lys Ser 
    770                 775                 780                 


Asn Glu Glu Asn Pro Glu His Ser Tyr Asp Lys Val Gly Thr Tyr Thr 
785                 790                 795                 800 


Val Lys Leu Lys Val Thr Asp Asp Lys Gly Glu Ser Ser Val Ser Thr 
                805                 810                 815     


Thr Thr Ala Glu Ile Lys Asp Leu Ser Glu Asn Lys Leu Pro Val Ile 
            820                 825                 830         


Tyr Met His Val Pro Lys Ser Gly Ala Leu Asn Gln Lys Val Val Phe 
        835                 840                 845             


Tyr Gly Lys Gly Thr Tyr Asp Pro Asp Gly Ser Ile Ala Gly Tyr Gln 
    850                 855                 860                 


Trp Asp Phe Gly Asp Gly Ser Asp Phe Ser Ser Glu Gln Asn Pro Ser 
865                 870                 875                 880 


His Val Tyr Thr Lys Lys Gly Glu Tyr Thr Val Thr Leu Arg Val Met 
                885                 890                 895     


Asp Ser Ser Gly Gln Met Ser Glu Lys Thr Met Lys Ile Lys Ile Thr 
            900                 905                 910         


Asp Pro Val Tyr Pro Ile Gly Thr Glu Lys Glu Pro Asn Asn Ser Lys 
        915                 920                 925             


Glu Thr Ala Ser Gly Pro Ile Val Pro Gly Ile Pro Val Ser Gly Thr 
    930                 935                 940                 


Ile Glu Asn Thr Ser Asp Gln Asp Tyr Phe Tyr Phe Asp Val Ile Thr 
945                 950                 955                 960 


Pro Gly Glu Val Lys Ile Asp Ile Asn Lys Leu Gly Tyr Gly Gly Ala 
                965                 970                 975     


Thr Trp Val Val Tyr Asp Glu Asn Asn Asn Ala Val Ser Tyr Ala Thr 
            980                 985                 990         


Asp Asp Gly Gln Asn Leu Ser Gly  Lys Phe Lys Ala Asp  Lys Pro Gly 
        995                 1000                 1005             


Arg Tyr  Tyr Ile His Leu Tyr  Met Phe Asn Gly Ser  Tyr Met Pro 
    1010                 1015                 1020             


Tyr Arg  Ile Asn Ile Glu Gly  Ser Val Gly Arg 
    1025                 1030                 


<210>  13
<211>  1021
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  13

Met Lys Arg Lys Cys Leu Ser Lys Arg Leu Met Leu Ala Ile Thr Met 
1               5                   10                  15      


Ala Thr Ile Phe Thr Val Asn Ser Thr Leu Pro Ile Tyr Ala Ala Val 
            20                  25                  30          


Asp Lys Asn Asn Ala Thr Ala Ala Val Gln Asn Glu Ser Lys Arg Tyr 
        35                  40                  45              


Thr Val Ser Tyr Leu Lys Thr Leu Asn Tyr Tyr Asp Leu Val Asp Leu 
    50                  55                  60                  


Leu Val Lys Thr Glu Ile Glu Asn Leu Pro Asp Leu Phe Gln Tyr Ser 
65                  70                  75                  80  


Ser Asp Ala Lys Glu Phe Tyr Gly Asn Lys Thr Arg Met Ser Phe Ile 
                85                  90                  95      


Met Asp Glu Ile Gly Arg Arg Ala Pro Gln Tyr Thr Glu Ile Asp His 
            100                 105                 110         


Lys Gly Ile Pro Thr Leu Val Glu Val Val Arg Ala Gly Phe Tyr Leu 
        115                 120                 125             


Gly Phe His Asn Lys Glu Leu Asn Glu Ile Asn Lys Arg Ser Phe Lys 
    130                 135                 140                 


Glu Arg Val Ile Pro Ser Ile Leu Ala Ile Gln Lys Asn Pro Asn Phe 
145                 150                 155                 160 


Lys Leu Gly Thr Glu Val Gln Asp Lys Ile Val Ser Ala Thr Gly Leu 
                165                 170                 175     


Leu Ala Gly Asn Glu Thr Ala Pro Pro Glu Val Val Asn Asn Phe Thr 
            180                 185                 190         


Pro Ile Leu Gln Asp Cys Ile Lys Asn Ile Asp Arg Tyr Ala Leu Asp 
        195                 200                 205             


Asp Leu Lys Ser Lys Ala Leu Phe Asn Val Leu Ala Ala Pro Thr Tyr 
    210                 215                 220                 


Asp Ile Thr Glu Tyr Leu Arg Ala Thr Lys Glu Lys Pro Glu Asn Thr 
225                 230                 235                 240 


Pro Trp Tyr Gly Lys Ile Asp Gly Phe Ile Asn Glu Leu Lys Lys Leu 
                245                 250                 255     


Ala Leu Tyr Gly Lys Ile Asn Asp Asn Asn Ser Trp Ile Ile Asp Asn 
            260                 265                 270         


Gly Ile Tyr His Ile Ala Pro Leu Gly Lys Leu His Ser Asn Asn Lys 
        275                 280                 285             


Ile Gly Ile Glu Thr Leu Thr Glu Val Met Lys Val Tyr Pro Tyr Leu 
    290                 295                 300                 


Ser Met Gln His Leu Gln Ser Ala Asp Gln Ile Lys Arg His Tyr Asp 
305                 310                 315                 320 


Ser Lys Asp Ala Glu Gly Asn Lys Ile Pro Leu Asp Lys Phe Lys Lys 
                325                 330                 335     


Glu Gly Lys Glu Lys Tyr Cys Pro Lys Thr Tyr Thr Phe Asp Asp Gly 
            340                 345                 350         


Lys Val Ile Ile Lys Ala Gly Ala Arg Val Glu Glu Glu Lys Val Lys 
        355                 360                 365             


Arg Leu Tyr Trp Ala Ser Lys Glu Val Asn Ser Gln Phe Phe Arg Val 
    370                 375                 380                 


Tyr Gly Ile Asp Lys Pro Leu Glu Glu Gly Asn Pro Asp Asp Ile Leu 
385                 390                 395                 400 


Thr Met Val Ile Tyr Asn Ser Pro Glu Glu Tyr Lys Leu Asn Ser Val 
                405                 410                 415     


Leu Tyr Gly Tyr Asp Thr Asn Asn Gly Gly Met Tyr Ile Glu Pro Glu 
            420                 425                 430         


Gly Thr Phe Phe Thr Tyr Glu Arg Glu Ala Gln Glu Ser Thr Tyr Thr 
        435                 440                 445             


Leu Glu Glu Leu Phe Arg His Glu Tyr Thr His Tyr Leu Gln Gly Arg 
    450                 455                 460                 


Tyr Ala Val Pro Gly Gln Trp Gly Arg Thr Lys Leu Tyr Asp Asn Asp 
465                 470                 475                 480 


Arg Leu Thr Trp Tyr Glu Glu Gly Gly Ala Glu Leu Phe Ala Gly Ser 
                485                 490                 495     


Thr Arg Thr Ser Gly Ile Leu Pro Arg Lys Ser Ile Val Ser Asn Ile 
            500                 505                 510         


His Asn Thr Thr Arg Asn Asn Arg Tyr Lys Leu Ser Asp Thr Val His 
        515                 520                 525             


Ser Lys Tyr Gly Ala Ser Phe Glu Phe Tyr Asn Tyr Ala Cys Met Phe 
    530                 535                 540                 


Met Asp Tyr Met Tyr Asn Lys Asp Met Gly Ile Leu Asn Lys Leu Asn 
545                 550                 555                 560 


Asp Leu Ala Lys Asn Asn Asp Val Asp Gly Tyr Asp Asn Tyr Ile Arg 
                565                 570                 575     


Asp Leu Ser Ser Asn Tyr Ala Leu Asn Asp Lys Tyr Gln Asp His Met 
            580                 585                 590         


Gln Glu Arg Ile Asp Asn Tyr Glu Asn Leu Thr Val Pro Phe Val Ala 
        595                 600                 605             


Asp Asp Tyr Leu Val Arg His Ala Tyr Lys Asn Pro Asn Glu Ile Tyr 
    610                 615                 620                 


Ser Glu Ile Ser Glu Val Ala Lys Leu Lys Asp Ala Lys Ser Glu Val 
625                 630                 635                 640 


Lys Lys Ser Gln Tyr Phe Ser Thr Phe Thr Leu Arg Gly Ser Tyr Thr 
                645                 650                 655     


Gly Gly Ala Ser Lys Gly Lys Leu Glu Asp Gln Lys Ala Met Asn Lys 
            660                 665                 670         


Phe Ile Asp Asp Ser Leu Lys Lys Leu Asp Thr Tyr Ser Trp Ser Gly 
        675                 680                 685             


Tyr Lys Thr Leu Thr Ala Tyr Phe Thr Asn Tyr Lys Val Asp Ser Ser 
    690                 695                 700                 


Asn Arg Val Thr Tyr Asp Val Val Phe His Gly Tyr Leu Pro Asn Glu 
705                 710                 715                 720 


Gly Asp Ser Lys Asn Ser Leu Pro Tyr Gly Lys Ile Asn Gly Thr Tyr 
                725                 730                 735     


Lys Gly Thr Glu Lys Glu Lys Ile Lys Phe Ser Ser Glu Gly Ser Phe 
            740                 745                 750         


Asp Pro Asp Gly Lys Ile Val Ser Tyr Glu Trp Asp Phe Gly Asp Gly 
        755                 760                 765             


Asn Lys Ser Asn Glu Glu Asn Pro Glu His Ser Tyr Asp Lys Val Gly 
    770                 775                 780                 


Thr Tyr Thr Val Lys Leu Lys Val Thr Asp Asp Lys Gly Glu Ser Ser 
785                 790                 795                 800 


Val Ser Thr Thr Thr Ala Glu Ile Lys Asp Leu Ser Glu Asn Lys Leu 
                805                 810                 815     


Pro Val Ile Tyr Met His Val Pro Lys Ser Gly Ala Leu Asn Gln Lys 
            820                 825                 830         


Val Val Phe Tyr Gly Lys Gly Thr Tyr Asp Pro Asp Gly Ser Ile Ala 
        835                 840                 845             


Gly Tyr Gln Trp Asp Phe Gly Asp Gly Ser Asp Phe Ser Ser Glu Gln 
    850                 855                 860                 


Asn Pro Ser His Val Tyr Thr Lys Lys Gly Glu Tyr Thr Val Thr Leu 
865                 870                 875                 880 


Arg Val Met Asp Ser Ser Gly Gln Met Ser Glu Lys Thr Met Lys Ile 
                885                 890                 895     


Lys Ile Thr Asp Pro Val Tyr Pro Ile Gly Thr Glu Lys Glu Pro Asn 
            900                 905                 910         


Asn Ser Lys Glu Thr Ala Ser Gly Pro Ile Val Pro Gly Ile Pro Val 
        915                 920                 925             


Ser Gly Thr Ile Glu Asn Thr Ser Asp Gln Asp Tyr Phe Tyr Phe Asp 
    930                 935                 940                 


Val Ile Thr Pro Gly Glu Val Lys Ile Asp Ile Asn Lys Leu Gly Tyr 
945                 950                 955                 960 


Gly Gly Ala Thr Trp Val Val Tyr Asp Glu Asn Asn Asn Ala Val Ser 
                965                 970                 975     


Tyr Ala Thr Asp Asp Gly Gln Asn Leu Ser Gly Lys Phe Lys Ala Asp 
            980                 985                 990         


Lys Pro Gly Arg Tyr Tyr Ile His  Leu Tyr Met Phe Asn  Gly Ser Tyr 
        995                 1000                 1005             


Met Pro  Tyr Arg Ile Asn Ile  Glu Gly Ser Val Gly  Arg 
    1010                 1015                 1020     


<210>  14
<211>  999
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  14

Met Lys Trp Val Thr Phe Ile Ser Leu Leu Phe Leu Phe Ser Ser Ala 
1               5                   10                  15      


Tyr Ser Val Gln Asn Glu Ser Lys Arg Tyr Thr Val Ser Tyr Leu Lys 
            20                  25                  30          


Thr Leu Asn Tyr Tyr Asp Leu Val Asp Leu Leu Val Lys Thr Glu Ile 
        35                  40                  45              


Glu Asn Leu Pro Asp Leu Phe Gln Tyr Ser Ser Asp Ala Lys Glu Phe 
    50                  55                  60                  


Tyr Gly Asn Lys Thr Arg Met Ser Phe Ile Met Asp Glu Ile Gly Arg 
65                  70                  75                  80  


Arg Ala Pro Gln Tyr Thr Glu Ile Asp His Lys Gly Ile Pro Thr Leu 
                85                  90                  95      


Val Glu Val Val Arg Ala Gly Phe Tyr Leu Gly Phe His Asn Lys Glu 
            100                 105                 110         


Leu Asn Glu Ile Asn Lys Arg Ser Phe Lys Glu Arg Val Ile Pro Ser 
        115                 120                 125             


Ile Leu Ala Ile Gln Lys Asn Pro Asn Phe Lys Leu Gly Thr Glu Val 
    130                 135                 140                 


Gln Asp Lys Ile Val Ser Ala Thr Gly Leu Leu Ala Gly Asn Glu Thr 
145                 150                 155                 160 


Ala Pro Pro Glu Val Val Asn Asn Phe Thr Pro Ile Leu Gln Asp Cys 
                165                 170                 175     


Ile Lys Asn Ile Asp Arg Tyr Ala Leu Asp Asp Leu Lys Ser Lys Ala 
            180                 185                 190         


Leu Phe Asn Val Leu Ala Ala Pro Thr Tyr Asp Ile Thr Glu Tyr Leu 
        195                 200                 205             


Arg Ala Thr Lys Glu Lys Pro Glu Asn Thr Pro Trp Tyr Gly Lys Ile 
    210                 215                 220                 


Asp Gly Phe Ile Asn Glu Leu Lys Lys Leu Ala Leu Tyr Gly Lys Ile 
225                 230                 235                 240 


Asn Asp Asn Asn Ser Trp Ile Ile Asp Asn Gly Ile Tyr His Ile Ala 
                245                 250                 255     


Pro Leu Gly Lys Leu His Ser Asn Asn Lys Ile Gly Ile Glu Thr Leu 
            260                 265                 270         


Thr Glu Val Met Lys Val Tyr Pro Tyr Leu Ser Met Gln His Leu Gln 
        275                 280                 285             


Ser Ala Asp Gln Ile Lys Arg His Tyr Asp Ser Lys Asp Ala Glu Gly 
    290                 295                 300                 


Asn Lys Ile Pro Leu Asp Lys Phe Lys Lys Glu Gly Lys Glu Lys Tyr 
305                 310                 315                 320 


Cys Pro Lys Thr Tyr Thr Phe Asp Asp Gly Lys Val Ile Ile Lys Ala 
                325                 330                 335     


Gly Ala Arg Val Glu Glu Glu Lys Val Lys Arg Leu Tyr Trp Ala Ser 
            340                 345                 350         


Lys Glu Val Asn Ser Gln Phe Phe Arg Val Tyr Gly Ile Asp Lys Pro 
        355                 360                 365             


Leu Glu Glu Gly Asn Pro Asp Asp Ile Leu Thr Met Val Ile Tyr Asn 
    370                 375                 380                 


Ser Pro Glu Glu Tyr Lys Leu Asn Ser Val Leu Tyr Gly Tyr Asp Thr 
385                 390                 395                 400 


Asn Asn Gly Gly Met Tyr Ile Glu Pro Glu Gly Thr Phe Phe Thr Tyr 
                405                 410                 415     


Glu Arg Glu Ala Gln Glu Ser Thr Tyr Thr Leu Glu Glu Leu Phe Arg 
            420                 425                 430         


His Glu Tyr Thr His Tyr Leu Gln Gly Arg Tyr Ala Val Pro Gly Gln 
        435                 440                 445             


Trp Gly Arg Thr Lys Leu Tyr Asp Asn Asp Arg Leu Thr Trp Tyr Glu 
    450                 455                 460                 


Glu Gly Gly Ala Glu Leu Phe Ala Gly Ser Thr Arg Thr Ser Gly Ile 
465                 470                 475                 480 


Leu Pro Arg Lys Ser Ile Val Ser Asn Ile His Asn Thr Thr Arg Asn 
                485                 490                 495     


Asn Arg Tyr Lys Leu Ser Asp Thr Val His Ser Lys Tyr Gly Ala Ser 
            500                 505                 510         


Phe Glu Phe Tyr Asn Tyr Ala Cys Met Phe Met Asp Tyr Met Tyr Asn 
        515                 520                 525             


Lys Asp Met Gly Ile Leu Asn Lys Leu Asn Asp Leu Ala Lys Asn Asn 
    530                 535                 540                 


Asp Val Asp Gly Tyr Asp Asn Tyr Ile Arg Asp Leu Ser Ser Asn Tyr 
545                 550                 555                 560 


Ala Leu Asn Asp Lys Tyr Gln Asp His Met Gln Glu Arg Ile Asp Asn 
                565                 570                 575     


Tyr Glu Asn Leu Thr Val Pro Phe Val Ala Asp Asp Tyr Leu Val Arg 
            580                 585                 590         


His Ala Tyr Lys Asn Pro Asn Glu Ile Tyr Ser Glu Ile Ser Glu Val 
        595                 600                 605             


Ala Lys Leu Lys Asp Ala Lys Ser Glu Val Lys Lys Ser Gln Tyr Phe 
    610                 615                 620                 


Ser Thr Phe Thr Leu Arg Gly Ser Tyr Thr Gly Gly Ala Ser Lys Gly 
625                 630                 635                 640 


Lys Leu Glu Asp Gln Lys Ala Met Asn Lys Phe Ile Asp Asp Ser Leu 
                645                 650                 655     


Lys Lys Leu Asp Thr Tyr Ser Trp Ser Gly Tyr Lys Thr Leu Thr Ala 
            660                 665                 670         


Tyr Phe Thr Asn Tyr Lys Val Asp Ser Ser Asn Arg Val Thr Tyr Asp 
        675                 680                 685             


Val Val Phe His Gly Tyr Leu Pro Asn Glu Gly Asp Ser Lys Asn Ser 
    690                 695                 700                 


Leu Pro Tyr Gly Lys Ile Asn Gly Thr Tyr Lys Gly Thr Glu Lys Glu 
705                 710                 715                 720 


Lys Ile Lys Phe Ser Ser Glu Gly Ser Phe Asp Pro Asp Gly Lys Ile 
                725                 730                 735     


Val Ser Tyr Glu Trp Asp Phe Gly Asp Gly Asn Lys Ser Asn Glu Glu 
            740                 745                 750         


Asn Pro Glu His Ser Tyr Asp Lys Val Gly Thr Tyr Thr Val Lys Leu 
        755                 760                 765             


Lys Val Thr Asp Asp Lys Gly Glu Ser Ser Val Ser Thr Thr Thr Ala 
    770                 775                 780                 


Glu Ile Lys Asp Leu Ser Glu Asn Lys Leu Pro Val Ile Tyr Met His 
785                 790                 795                 800 


Val Pro Lys Ser Gly Ala Leu Asn Gln Lys Val Val Phe Tyr Gly Lys 
                805                 810                 815     


Gly Thr Tyr Asp Pro Asp Gly Ser Ile Ala Gly Tyr Gln Trp Asp Phe 
            820                 825                 830         


Gly Asp Gly Ser Asp Phe Ser Ser Glu Gln Asn Pro Ser His Val Tyr 
        835                 840                 845             


Thr Lys Lys Gly Glu Tyr Thr Val Thr Leu Arg Val Met Asp Ser Ser 
    850                 855                 860                 


Gly Gln Met Ser Glu Lys Thr Met Lys Ile Lys Ile Thr Asp Pro Val 
865                 870                 875                 880 


Tyr Pro Ile Gly Thr Glu Lys Glu Pro Asn Asn Ser Lys Glu Thr Ala 
                885                 890                 895     


Ser Gly Pro Ile Val Pro Gly Ile Pro Val Ser Gly Thr Ile Glu Asn 
            900                 905                 910         


Thr Ser Asp Gln Asp Tyr Phe Tyr Phe Asp Val Ile Thr Pro Gly Glu 
        915                 920                 925             


Val Lys Ile Asp Ile Asn Lys Leu Gly Tyr Gly Gly Ala Thr Trp Val 
    930                 935                 940                 


Val Tyr Asp Glu Asn Asn Asn Ala Val Ser Tyr Ala Thr Asp Asp Gly 
945                 950                 955                 960 


Gln Asn Leu Ser Gly Lys Phe Lys Ala Asp Lys Pro Gly Arg Tyr Tyr 
                965                 970                 975     


Ile His Leu Tyr Met Phe Asn Gly Ser Tyr Met Pro Tyr Arg Ile Asn 
            980                 985                 990         


Ile Glu Gly Ser Val Gly Arg 
        995                 


<210>  15
<211>  1045
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  15

Met Lys Trp Val Thr Phe Ile Ser Leu Leu Phe Leu Phe Ser Ser Ala 
1               5                   10                  15      


Tyr Ser Met Lys Arg Lys Cys Leu Ser Lys Arg Leu Met Leu Ala Ile 
            20                  25                  30          


Thr Met Ala Thr Ile Phe Thr Val Asn Ser Thr Leu Pro Ile Tyr Ala 
        35                  40                  45              


Ala Val Asp Lys Asn Asn Ala Thr Ala Ala Arg Arg Arg Arg Lys Arg 
    50                  55                  60                  


Val Gln Asn Glu Ser Lys Arg Tyr Thr Val Ser Tyr Leu Lys Thr Leu 
65                  70                  75                  80  


Asn Tyr Tyr Asp Leu Val Asp Leu Leu Val Lys Thr Glu Ile Glu Asn 
                85                  90                  95      


Leu Pro Asp Leu Phe Gln Tyr Ser Ser Asp Ala Lys Glu Phe Tyr Gly 
            100                 105                 110         


Asn Lys Thr Arg Met Ser Phe Ile Met Asp Glu Ile Gly Arg Arg Ala 
        115                 120                 125             


Pro Gln Tyr Thr Glu Ile Asp His Lys Gly Ile Pro Thr Leu Val Glu 
    130                 135                 140                 


Val Val Arg Ala Gly Phe Tyr Leu Gly Phe His Asn Lys Glu Leu Asn 
145                 150                 155                 160 


Glu Ile Asn Lys Arg Ser Phe Lys Glu Arg Val Ile Pro Ser Ile Leu 
                165                 170                 175     


Ala Ile Gln Lys Asn Pro Asn Phe Lys Leu Gly Thr Glu Val Gln Asp 
            180                 185                 190         


Lys Ile Val Ser Ala Thr Gly Leu Leu Ala Gly Asn Glu Thr Ala Pro 
        195                 200                 205             


Pro Glu Val Val Asn Asn Phe Thr Pro Ile Leu Gln Asp Cys Ile Lys 
    210                 215                 220                 


Asn Ile Asp Arg Tyr Ala Leu Asp Asp Leu Lys Ser Lys Ala Leu Phe 
225                 230                 235                 240 


Asn Val Leu Ala Ala Pro Thr Tyr Asp Ile Thr Glu Tyr Leu Arg Ala 
                245                 250                 255     


Thr Lys Glu Lys Pro Glu Asn Thr Pro Trp Tyr Gly Lys Ile Asp Gly 
            260                 265                 270         


Phe Ile Asn Glu Leu Lys Lys Leu Ala Leu Tyr Gly Lys Ile Asn Asp 
        275                 280                 285             


Asn Asn Ser Trp Ile Ile Asp Asn Gly Ile Tyr His Ile Ala Pro Leu 
    290                 295                 300                 


Gly Lys Leu His Ser Asn Asn Lys Ile Gly Ile Glu Thr Leu Thr Glu 
305                 310                 315                 320 


Val Met Lys Val Tyr Pro Tyr Leu Ser Met Gln His Leu Gln Ser Ala 
                325                 330                 335     


Asp Gln Ile Lys Arg His Tyr Asp Ser Lys Asp Ala Glu Gly Asn Lys 
            340                 345                 350         


Ile Pro Leu Asp Lys Phe Lys Lys Glu Gly Lys Glu Lys Tyr Cys Pro 
        355                 360                 365             


Lys Thr Tyr Thr Phe Asp Asp Gly Lys Val Ile Ile Lys Ala Gly Ala 
    370                 375                 380                 


Arg Val Glu Glu Glu Lys Val Lys Arg Leu Tyr Trp Ala Ser Lys Glu 
385                 390                 395                 400 


Val Asn Ser Gln Phe Phe Arg Val Tyr Gly Ile Asp Lys Pro Leu Glu 
                405                 410                 415     


Glu Gly Asn Pro Asp Asp Ile Leu Thr Met Val Ile Tyr Asn Ser Pro 
            420                 425                 430         


Glu Glu Tyr Lys Leu Asn Ser Val Leu Tyr Gly Tyr Asp Thr Asn Asn 
        435                 440                 445             


Gly Gly Met Tyr Ile Glu Pro Glu Gly Thr Phe Phe Thr Tyr Glu Arg 
    450                 455                 460                 


Glu Ala Gln Glu Ser Thr Tyr Thr Leu Glu Glu Leu Phe Arg His Glu 
465                 470                 475                 480 


Tyr Thr His Tyr Leu Gln Gly Arg Tyr Ala Val Pro Gly Gln Trp Gly 
                485                 490                 495     


Arg Thr Lys Leu Tyr Asp Asn Asp Arg Leu Thr Trp Tyr Glu Glu Gly 
            500                 505                 510         


Gly Ala Glu Leu Phe Ala Gly Ser Thr Arg Thr Ser Gly Ile Leu Pro 
        515                 520                 525             


Arg Lys Ser Ile Val Ser Asn Ile His Asn Thr Thr Arg Asn Asn Arg 
    530                 535                 540                 


Tyr Lys Leu Ser Asp Thr Val His Ser Lys Tyr Gly Ala Ser Phe Glu 
545                 550                 555                 560 


Phe Tyr Asn Tyr Ala Cys Met Phe Met Asp Tyr Met Tyr Asn Lys Asp 
                565                 570                 575     


Met Gly Ile Leu Asn Lys Leu Asn Asp Leu Ala Lys Asn Asn Asp Val 
            580                 585                 590         


Asp Gly Tyr Asp Asn Tyr Ile Arg Asp Leu Ser Ser Asn Tyr Ala Leu 
        595                 600                 605             


Asn Asp Lys Tyr Gln Asp His Met Gln Glu Arg Ile Asp Asn Tyr Glu 
    610                 615                 620                 


Asn Leu Thr Val Pro Phe Val Ala Asp Asp Tyr Leu Val Arg His Ala 
625                 630                 635                 640 


Tyr Lys Asn Pro Asn Glu Ile Tyr Ser Glu Ile Ser Glu Val Ala Lys 
                645                 650                 655     


Leu Lys Asp Ala Lys Ser Glu Val Lys Lys Ser Gln Tyr Phe Ser Thr 
            660                 665                 670         


Phe Thr Leu Arg Gly Ser Tyr Thr Gly Gly Ala Ser Lys Gly Lys Leu 
        675                 680                 685             


Glu Asp Gln Lys Ala Met Asn Lys Phe Ile Asp Asp Ser Leu Lys Lys 
    690                 695                 700                 


Leu Asp Thr Tyr Ser Trp Ser Gly Tyr Lys Thr Leu Thr Ala Tyr Phe 
705                 710                 715                 720 


Thr Asn Tyr Lys Val Asp Ser Ser Asn Arg Val Thr Tyr Asp Val Val 
                725                 730                 735     


Phe His Gly Tyr Leu Pro Asn Glu Gly Asp Ser Lys Asn Ser Leu Pro 
            740                 745                 750         


Tyr Gly Lys Ile Asn Gly Thr Tyr Lys Gly Thr Glu Lys Glu Lys Ile 
        755                 760                 765             


Lys Phe Ser Ser Glu Gly Ser Phe Asp Pro Asp Gly Lys Ile Val Ser 
    770                 775                 780                 


Tyr Glu Trp Asp Phe Gly Asp Gly Asn Lys Ser Asn Glu Glu Asn Pro 
785                 790                 795                 800 


Glu His Ser Tyr Asp Lys Val Gly Thr Tyr Thr Val Lys Leu Lys Val 
                805                 810                 815     


Thr Asp Asp Lys Gly Glu Ser Ser Val Ser Thr Thr Thr Ala Glu Ile 
            820                 825                 830         


Lys Asp Leu Ser Glu Asn Lys Leu Pro Val Ile Tyr Met His Val Pro 
        835                 840                 845             


Lys Ser Gly Ala Leu Asn Gln Lys Val Val Phe Tyr Gly Lys Gly Thr 
    850                 855                 860                 


Tyr Asp Pro Asp Gly Ser Ile Ala Gly Tyr Gln Trp Asp Phe Gly Asp 
865                 870                 875                 880 


Gly Ser Asp Phe Ser Ser Glu Gln Asn Pro Ser His Val Tyr Thr Lys 
                885                 890                 895     


Lys Gly Glu Tyr Thr Val Thr Leu Arg Val Met Asp Ser Ser Gly Gln 
            900                 905                 910         


Met Ser Glu Lys Thr Met Lys Ile Lys Ile Thr Asp Pro Val Tyr Pro 
        915                 920                 925             


Ile Gly Thr Glu Lys Glu Pro Asn Asn Ser Lys Glu Thr Ala Ser Gly 
    930                 935                 940                 


Pro Ile Val Pro Gly Ile Pro Val Ser Gly Thr Ile Glu Asn Thr Ser 
945                 950                 955                 960 


Asp Gln Asp Tyr Phe Tyr Phe Asp Val Ile Thr Pro Gly Glu Val Lys 
                965                 970                 975     


Ile Asp Ile Asn Lys Leu Gly Tyr Gly Gly Ala Thr Trp Val Val Tyr 
            980                 985                 990         


Asp Glu Asn Asn Asn Ala Val Ser  Tyr Ala Thr Asp Asp  Gly Gln Asn 
        995                 1000                 1005             


Leu Ser  Gly Lys Phe Lys Ala  Asp Lys Pro Gly Arg  Tyr Tyr Ile 
    1010                 1015                 1020             


His Leu  Tyr Met Phe Asn Gly  Ser Tyr Met Pro Tyr  Arg Ile Asn 
    1025                 1030                 1035             


Ile Glu  Gly Ser Val Gly Arg  
    1040                 1045 


<210>  16
<211>  191
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  16

Met Gly Thr Trp Ile Leu Phe Ala Cys Leu Leu Gly Ala Ala Phe Ala 
1               5                   10                  15      


Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
            20                  25                  30          


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Ser Ile Arg Pro Pro 
        35                  40                  45              


Tyr Pro Ser Tyr Gly Tyr Glu Pro Met Gly Gly Trp Leu His His Gln 
    50                  55                  60                  


Ile Ile Pro Val Leu Ser Gln Gln His Pro Pro Thr His Thr Leu Gln 
65                  70                  75                  80  


Pro His His His Ile Pro Val Val Pro Ala Gln Gln Pro Val Ile Pro 
                85                  90                  95      


Gln Gln Pro Met Met Pro Val Pro Gly Gln His Ser Met Thr Pro Ile 
            100                 105                 110         


Gln His His Gln Pro Asn Leu Pro Pro Pro Ala Gln Gln Pro Tyr Gln 
        115                 120                 125             


Pro Gln Pro Val Gln Pro Gln Pro His Gln Pro Met Gln Pro Gln Pro 
    130                 135                 140                 


Pro Val His Pro Met Gln Pro Leu Pro Pro Gln Pro Pro Leu Pro Pro 
145                 150                 155                 160 


Met Phe Pro Met Gln Pro Leu Pro Pro Met Leu Pro Asp Leu Thr Leu 
                165                 170                 175     


Glu Ala Trp Pro Ser Thr Asp Lys Thr Lys Arg Glu Glu Val Asp 
            180                 185                 190     


<210>  17
<211>  44
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  17

Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
1               5                   10                  15      


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Ser Ile Arg Pro Pro 
            20                  25                  30          


Tyr Pro Ser Tyr Gly Tyr Glu Pro Met Gly Gly Trp 
        35                  40                  


<210>  18
<211>  55
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  18

Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
1               5                   10                  15      


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Ser Ile Arg Pro Pro 
            20                  25                  30          


Pro Met Leu Pro Asp Leu Thr Leu Glu Ala Trp Pro Ser Thr Asp Lys 
        35                  40                  45              


Thr Lys Arg Glu Glu Val Asp 
    50                  55  


<210>  19
<211>  68
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  19

Met Ala Val Met Ala Pro Arg Thr Leu Val Leu Leu Leu Ser Gly Ala 
1               5                   10                  15      


Leu Ala Leu Thr Gln Thr Trp Ala Met Pro Leu Pro Pro His Pro Gly 
            20                  25                  30          


His Pro Gly Tyr Ile Asn Phe Ser Tyr Glu Val Leu Thr Pro Leu Lys 
        35                  40                  45              


Trp Tyr Gln Ser Ile Arg Pro Pro Tyr Pro Ser Tyr Gly Tyr Glu Pro 
    50                  55                  60                  


Met Gly Gly Trp 
65              


<210>  20
<211>  79
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  20

Met Ala Val Met Ala Pro Arg Thr Leu Val Leu Leu Leu Ser Gly Ala 
1               5                   10                  15      


Leu Ala Leu Thr Gln Thr Trp Ala Met Pro Leu Pro Pro His Pro Gly 
            20                  25                  30          


His Pro Gly Tyr Ile Asn Phe Ser Tyr Glu Val Leu Thr Pro Leu Lys 
        35                  40                  45              


Trp Tyr Gln Ser Ile Arg Pro Pro Pro Met Leu Pro Asp Leu Thr Leu 
    50                  55                  60                  


Glu Ala Trp Pro Ser Thr Asp Lys Thr Lys Arg Glu Glu Val Asp 
65                  70                  75                  


<210>  21
<211>  192
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  21

Met Gly Thr Trp Ile Leu Phe Ala Cys Leu Val Gly Ala Ala Phe Ala 
1               5                   10                  15      


Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
            20                  25                  30          


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Ser Met Ile Arg Pro 
        35                  40                  45              


Pro Tyr Ser Ser Tyr Gly Tyr Glu Pro Met Gly Gly Trp Leu His His 
    50                  55                  60                  


Gln Ile Ile Pro Val Val Ser Gln Gln His Pro Leu Thr His Thr Leu 
65                  70                  75                  80  


Gln Ser His His His Ile Pro Val Val Pro Ala Gln Gln Pro Arg Val 
                85                  90                  95      


Arg Gln Gln Ala Leu Met Pro Val Pro Gly Gln Gln Ser Met Thr Pro 
            100                 105                 110         


Thr Gln His His Gln Pro Asn Leu Pro Leu Pro Ala Gln Gln Pro Phe 
        115                 120                 125             


Gln Pro Gln Pro Val Gln Pro Gln Pro His Gln Pro Met Gln Pro Gln 
    130                 135                 140                 


Pro Pro Val Gln Pro Met Gln Pro Leu Leu Pro Gln Pro Pro Leu Pro 
145                 150                 155                 160 


Pro Met Phe Pro Leu Arg Pro Leu Pro Pro Ile Leu Pro Asp Leu His 
                165                 170                 175     


Leu Glu Ala Trp Pro Ala Thr Asp Lys Thr Lys Gln Glu Glu Val Asp 
            180                 185                 190         


<210>  22
<211>  45
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  22

Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
1               5                   10                  15      


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Ser Met Ile Arg Pro 
            20                  25                  30          


Pro Tyr Ser Ser Tyr Gly Tyr Glu Pro Met Gly Gly Trp 
        35                  40                  45  


<210>  23
<211>  56
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  23

Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
1               5                   10                  15      


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Ser Met Ile Arg Pro 
            20                  25                  30          


Pro Pro Ile Leu Pro Asp Leu His Leu Glu Ala Trp Pro Ala Thr Asp 
        35                  40                  45              


Lys Thr Lys Gln Glu Glu Val Asp 
    50                  55      


<210>  24
<211>  69
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  24

Met Ala Val Met Ala Pro Arg Thr Leu Val Leu Leu Leu Ser Gly Ala 
1               5                   10                  15      


Leu Ala Leu Thr Gln Thr Trp Ala Met Pro Leu Pro Pro His Pro Gly 
            20                  25                  30          


His Pro Gly Tyr Ile Asn Phe Ser Tyr Glu Val Leu Thr Pro Leu Lys 
        35                  40                  45              


Trp Tyr Gln Ser Met Ile Arg Pro Pro Tyr Ser Ser Tyr Gly Tyr Glu 
    50                  55                  60                  


Pro Met Gly Gly Trp 
65                  


<210>  25
<211>  80
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  25

Met Ala Val Met Ala Pro Arg Thr Leu Val Leu Leu Leu Ser Gly Ala 
1               5                   10                  15      


Leu Ala Leu Thr Gln Thr Trp Ala Met Pro Leu Pro Pro His Pro Gly 
            20                  25                  30          


His Pro Gly Tyr Ile Asn Phe Ser Tyr Glu Val Leu Thr Pro Leu Lys 
        35                  40                  45              


Trp Tyr Gln Ser Met Ile Arg Pro Pro Pro Ile Leu Pro Asp Leu His 
    50                  55                  60                  


Leu Glu Ala Trp Pro Ala Thr Asp Lys Thr Lys Gln Glu Glu Val Asp 
65                  70                  75                  80  


<210>  26
<211>  189
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  26

Met Gly Thr Trp Ile Leu Phe Ala Cys Leu Leu Gly Ala Ala Phe Ser 
1               5                   10                  15      


Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
            20                  25                  30          


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Asn Met Ile Arg His 
        35                  40                  45              


Pro Tyr Thr Ser Tyr Gly Tyr Glu Pro Met Gly Gly Trp Leu His His 
    50                  55                  60                  


Gln Ile Ile Pro Val Val Ser Gln Gln Thr Pro Gln Ser His Ala Leu 
65                  70                  75                  80  


Gln Pro His His His Ile Pro Met Val Pro Ala Gln Gln Pro Gly Ile 
                85                  90                  95      


Pro Gln Gln Pro Met Met Pro Leu Pro Gly Gln His Ser Met Thr Pro 
            100                 105                 110         


Thr Gln His His Gln Pro Asn Leu Pro Leu Pro Ala Gln Gln Pro Phe 
        115                 120                 125             


Gln Pro Gln Pro Val Gln Pro Gln Pro His Gln Pro Leu Gln Pro Gln 
    130                 135                 140                 


Ser Pro Met His Pro Ile Gln Pro Leu Leu Pro Gln Pro Pro Leu Pro 
145                 150                 155                 160 


Pro Met Phe Ser Met Gln Ser Leu Leu Pro Asp Leu Pro Leu Glu Ala 
                165                 170                 175     


Trp Pro Ala Thr Asp Lys Thr Lys Arg Glu Glu Val Asp 
            180                 185                 


<210>  27
<211>  45
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  27

Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
1               5                   10                  15      


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Asn Met Ile Arg His 
            20                  25                  30          


Pro Tyr Thr Ser Tyr Gly Tyr Glu Pro Met Gly Gly Trp 
        35                  40                  45  


<210>  28
<211>  56
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  28

Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
1               5                   10                  15      


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Asn Met Ile Arg His 
            20                  25                  30          


Pro Ser Leu Leu Pro Asp Leu Pro Leu Glu Ala Trp Pro Ala Thr Asp 
        35                  40                  45              


Lys Thr Lys Arg Glu Glu Val Asp 
    50                  55      


<210>  29
<211>  69
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  29

Met Ala Val Met Ala Pro Arg Thr Leu Val Leu Leu Leu Ser Gly Ala 
1               5                   10                  15      


Leu Ala Leu Thr Gln Thr Trp Ala Met Pro Leu Pro Pro His Pro Gly 
            20                  25                  30          


His Pro Gly Tyr Ile Asn Phe Ser Tyr Glu Val Leu Thr Pro Leu Lys 
        35                  40                  45              


Trp Tyr Gln Asn Met Ile Arg His Pro Tyr Thr Ser Tyr Gly Tyr Glu 
    50                  55                  60                  


Pro Met Gly Gly Trp 
65                  


<210>  30
<211>  80
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  30

Met Ala Val Met Ala Pro Arg Thr Leu Val Leu Leu Leu Ser Gly Ala 
1               5                   10                  15      


Leu Ala Leu Thr Gln Thr Trp Ala Met Pro Leu Pro Pro His Pro Gly 
            20                  25                  30          


His Pro Gly Tyr Ile Asn Phe Ser Tyr Glu Val Leu Thr Pro Leu Lys 
        35                  40                  45              


Trp Tyr Gln Asn Met Ile Arg His Pro Ser Leu Leu Pro Asp Leu Pro 
    50                  55                  60                  


Leu Glu Ala Trp Pro Ala Thr Asp Lys Thr Lys Arg Glu Glu Val Asp 
65                  70                  75                  80  


<210>  31
<211>  177
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  31

Met Gly Thr Trp Ile Leu Phe Ala Cys Leu Leu Gly Ala Ala Phe Ser 
1               5                   10                  15      


Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
            20                  25                  30          


Tyr Ile Arg His Pro Tyr Thr Ser Tyr Gly Tyr Glu Pro Met Gly Gly 
        35                  40                  45              


Trp Leu His His Gln Ile Ile Pro Val Val Ser Gln Gln Thr Pro Gln 
    50                  55                  60                  


Ser His Ala Leu Gln Pro His His His Ile Pro Met Val Pro Ala Gln 
65                  70                  75                  80  


Gln Pro Gly Ile Pro Gln Gln Pro Met Met Pro Leu Pro Gly Gln His 
                85                  90                  95      


Ser Met Thr Pro Thr Gln His His Gln Pro Asn Leu Pro Leu Pro Ala 
            100                 105                 110         


Gln Gln Pro Phe Gln Pro Gln Pro Val Gln Pro Gln Pro His Gln Pro 
        115                 120                 125             


Leu Gln Pro Gln Ser Pro Met His Pro Ile Gln Pro Leu Leu Pro Gln 
    130                 135                 140                 


Pro Pro Leu Pro Pro Met Phe Ser Met Gln Ser Leu Leu Pro Asp Leu 
145                 150                 155                 160 


Pro Leu Glu Ala Trp Pro Ala Thr Asp Lys Thr Lys Arg Glu Glu Val 
                165                 170                 175     


Asp 
    


<210>  32
<211>  189
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  32

Met Gly Thr Trp Ile Phe Phe Ala Cys Leu Leu Gly Ala Ser Leu Ala 
1               5                   10                  15      


Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
            20                  25                  30          


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Asn Met Ile Arg His 
        35                  40                  45              


Pro Tyr Thr Ser Tyr Gly Tyr Glu Pro Met Gly Gly Trp Leu His His 
    50                  55                  60                  


Gln Ile Ile Pro Val Val Ser Gln Gln Thr Pro Gln Ser His Ala Leu 
65                  70                  75                  80  


Gln Pro His His His Ile Pro Met Val Pro Ala Gln Gln Pro Gly Ile 
                85                  90                  95      


Pro Gln Gln Pro Met Met Pro Leu Pro Gly Gln His Ser Met Thr Pro 
            100                 105                 110         


Thr Gln His His Gln Pro Asn Leu Pro Leu Pro Ala Gln Gln Pro Phe 
        115                 120                 125             


Gln Pro Gln Pro Val Gln Pro Gln Pro His Gln Pro Leu Gln Pro Gln 
    130                 135                 140                 


Ser Pro Met His Pro Ile Gln Pro Leu Leu Pro Gln Pro Pro Leu Pro 
145                 150                 155                 160 


Pro Met Phe Ser Met Gln Ser Leu Leu Pro Asp Leu Pro Leu Glu Ala 
                165                 170                 175     


Trp Pro Ala Thr Asp Lys Thr Lys Arg Glu Glu Val Asp 
            180                 185                 


<210>  33
<211>  72
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  33

Met Gly Thr Trp Ile Leu Phe Ala Cys Leu Leu Gly Ala Ala Phe Ser 
1               5                   10                  15      


Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
            20                  25                  30          


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Asn Met Ile Arg His 
        35                  40                  45              


Pro Ser Leu Leu Pro Asp Leu Pro Leu Glu Ala Trp Pro Ala Thr Asp 
    50                  55                  60                  


Lys Thr Lys Arg Glu Glu Val Asp 
65                  70          


<210>  34
<211>  203
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  34

Met Gly Thr Trp Ile Leu Phe Ala Cys Leu Leu Gly Ala Ala Phe Ser 
1               5                   10                  15      


Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
            20                  25                  30          


Tyr Glu Asp Leu Tyr Leu Glu Ala Ile Arg Ile Asp Arg Thr Ala Phe 
        35                  40                  45              


Val Leu Thr Pro Leu Lys Trp Tyr Gln Asn Met Ile Arg His Pro Tyr 
    50                  55                  60                  


Thr Ser Tyr Gly Tyr Glu Pro Met Gly Gly Trp Leu His His Gln Ile 
65                  70                  75                  80  


Ile Pro Val Val Ser Gln Gln Thr Pro Gln Ser His Ala Leu Gln Pro 
                85                  90                  95      


His His His Ile Pro Met Val Pro Ala Gln Gln Pro Gly Ile Pro Gln 
            100                 105                 110         


Gln Pro Met Met Pro Leu Pro Gly Gln His Ser Met Thr Pro Thr Gln 
        115                 120                 125             


His His Gln Pro Asn Leu Pro Leu Pro Ala Gln Gln Pro Phe Gln Pro 
    130                 135                 140                 


Gln Pro Val Gln Pro Gln Pro His Gln Pro Leu Gln Pro Gln Ser Pro 
145                 150                 155                 160 


Met His Pro Ile Gln Pro Leu Leu Pro Gln Pro Pro Leu Pro Pro Met 
                165                 170                 175     


Phe Ser Met Gln Ser Leu Leu Pro Asp Leu Pro Leu Glu Ala Trp Pro 
            180                 185                 190         


Ala Thr Asp Lys Thr Lys Arg Glu Glu Val Asp 
        195                 200             


<210>  35
<211>  165
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  35

Met Gly Thr Trp Ile Leu Phe Ala Cys Leu Leu Gly Ala Ala Phe Ser 
1               5                   10                  15      


Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
            20                  25                  30          


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Asn Met Ile Arg His 
        35                  40                  45              


Pro Thr Pro Gln Ser His Ala Leu Gln Pro His His His Ile Pro Met 
    50                  55                  60                  


Val Pro Ala Gln Gln Pro Gly Ile Pro Gln Gln Pro Met Met Pro Leu 
65                  70                  75                  80  


Pro Gly Gln His Ser Met Thr Pro Thr Gln His His Gln Pro Asn Leu 
                85                  90                  95      


Pro Leu Pro Ala Gln Gln Pro Phe Gln Pro Gln Pro Val Gln Pro Gln 
            100                 105                 110         


Pro His Gln Pro Leu Gln Pro Gln Ser Pro Met His Pro Ile Gln Pro 
        115                 120                 125             


Leu Leu Pro Gln Pro Pro Leu Pro Pro Met Phe Ser Met Gln Ser Leu 
    130                 135                 140                 


Leu Pro Asp Leu Pro Leu Glu Ala Trp Pro Ala Thr Asp Lys Thr Lys 
145                 150                 155                 160 


Arg Glu Glu Val Asp 
                165 


<210>  36
<211>  173
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  36

Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
1               5                   10                  15      


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Asn Met Ile Arg His 
            20                  25                  30          


Pro Tyr Thr Ser Tyr Gly Tyr Glu Pro Met Gly Gly Trp Leu His His 
        35                  40                  45              


Gln Ile Ile Pro Val Val Ser Gln Gln Thr Pro Gln Ser His Ala Leu 
    50                  55                  60                  


Gln Pro His His His Ile Pro Met Val Pro Ala Gln Gln Pro Gly Ile 
65                  70                  75                  80  


Pro Gln Gln Pro Met Met Pro Leu Pro Gly Gln His Ser Met Thr Pro 
                85                  90                  95      


Thr Gln His His Gln Pro Asn Leu Pro Leu Pro Ala Gln Gln Pro Phe 
            100                 105                 110         


Gln Pro Gln Pro Val Gln Pro Gln Pro His Gln Pro Leu Gln Pro Gln 
        115                 120                 125             


Ser Pro Met His Pro Ile Gln Pro Leu Leu Pro Gln Pro Pro Leu Pro 
    130                 135                 140                 


Pro Met Phe Ser Met Gln Ser Leu Leu Pro Asp Leu Pro Leu Glu Ala 
145                 150                 155                 160 


Trp Pro Ala Thr Asp Lys Thr Lys Arg Glu Glu Val Asp 
                165                 170             


<210>  37
<211>  986
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  37

Met Pro Gly Val Ala Arg Leu Pro Leu Leu Leu Gly Leu Leu Leu Leu 
1               5                   10                  15      


Pro Arg Pro Gly Arg Pro Leu Asp Leu Ala Asp Tyr Thr Tyr Asp Leu 
            20                  25                  30          


Ala Glu Glu Asp Asp Ser Glu Pro Leu Asn Tyr Lys Asp Pro Cys Lys 
        35                  40                  45              


Ala Ala Ala Phe Leu Gly Asp Ile Ala Leu Asp Glu Glu Asp Leu Arg 
    50                  55                  60                  


Ala Phe Gln Val Gln Gln Ala Val Asp Leu Arg Arg His Thr Ala Arg 
65                  70                  75                  80  


Lys Ser Ser Ile Lys Ala Ala Val Pro Gly Asn Thr Ser Thr Pro Ser 
                85                  90                  95      


Cys Gln Ser Thr Asn Gly Gln Pro Gln Arg Gly Ala Cys Gly Arg Trp 
            100                 105                 110         


Arg Gly Arg Ser Arg Ser Arg Arg Ala Ala Thr Ser Arg Pro Glu Arg 
        115                 120                 125             


Val Trp Pro Asp Gly Val Ile Pro Phe Val Ile Gly Gly Asn Phe Thr 
    130                 135                 140                 


Gly Ser Gln Arg Ala Val Phe Arg Gln Ala Met Arg His Trp Glu Lys 
145                 150                 155                 160 


His Thr Cys Val Thr Phe Leu Glu Arg Thr Asp Glu Asp Ser Tyr Ile 
                165                 170                 175     


Val Phe Thr Tyr Arg Pro Cys Gly Cys Cys Ser Tyr Val Gly Arg Arg 
            180                 185                 190         


Gly Gly Gly Pro Gln Ala Ile Ser Ile Gly Lys Asn Cys Asp Lys Phe 
        195                 200                 205             


Gly Ile Val Val His Glu Leu Gly His Val Val Gly Phe Trp His Glu 
    210                 215                 220                 


His Thr Arg Pro Asp Arg Asp Arg His Val Ser Ile Val Arg Glu Asn 
225                 230                 235                 240 


Ile Gln Pro Gly Gln Glu Tyr Asn Phe Leu Lys Met Glu Pro Gln Glu 
                245                 250                 255     


Val Glu Ser Leu Gly Glu Thr Tyr Asp Phe Asp Ser Ile Met His Tyr 
            260                 265                 270         


Ala Arg Asn Thr Phe Ser Arg Gly Ile Phe Leu Asp Thr Ile Val Pro 
        275                 280                 285             


Lys Tyr Glu Val Asn Gly Val Lys Pro Pro Ile Gly Gln Arg Thr Arg 
    290                 295                 300                 


Leu Ser Lys Gly Asp Ile Ala Gln Ala Arg Lys Leu Tyr Lys Cys Pro 
305                 310                 315                 320 


Ala Cys Gly Glu Thr Leu Gln Asp Ser Thr Gly Asn Phe Ser Ser Pro 
                325                 330                 335     


Glu Tyr Pro Asn Gly Tyr Ser Ala His Met His Cys Val Trp Arg Ile 
            340                 345                 350         


Ser Val Thr Pro Gly Glu Lys Ile Ile Leu Asn Phe Thr Ser Leu Asp 
        355                 360                 365             


Leu Tyr Arg Ser Arg Leu Cys Trp Tyr Asp Tyr Val Glu Val Arg Asp 
    370                 375                 380                 


Gly Phe Trp Arg Lys Ala Pro Leu Arg Gly Arg Phe Cys Gly Ser Lys 
385                 390                 395                 400 


Leu Pro Glu Pro Ile Val Ser Thr Asp Ser Arg Leu Trp Val Glu Phe 
                405                 410                 415     


Arg Ser Ser Ser Asn Trp Val Gly Lys Gly Phe Phe Ala Val Tyr Glu 
            420                 425                 430         


Ala Ile Cys Gly Gly Asp Val Lys Lys Asp Tyr Gly His Ile Gln Ser 
        435                 440                 445             


Pro Asn Tyr Pro Asp Asp Tyr Arg Pro Ser Lys Val Cys Ile Trp Arg 
    450                 455                 460                 


Ile Gln Val Ser Glu Gly Phe His Val Gly Leu Thr Phe Gln Ser Phe 
465                 470                 475                 480 


Glu Ile Glu Arg His Asp Ser Cys Ala Tyr Asp Tyr Leu Glu Val Arg 
                485                 490                 495     


Asp Gly His Ser Glu Ser Ser Thr Leu Ile Gly Arg Tyr Cys Gly Tyr 
            500                 505                 510         


Glu Lys Pro Asp Asp Ile Lys Ser Thr Ser Ser Arg Leu Trp Leu Lys 
        515                 520                 525             


Phe Val Ser Asp Gly Ser Ile Asn Lys Ala Gly Phe Ala Val Asn Phe 
    530                 535                 540                 


Phe Lys Glu Val Asp Glu Cys Ser Arg Pro Asn Arg Gly Gly Cys Glu 
545                 550                 555                 560 


Gln Arg Cys Leu Asn Thr Leu Gly Ser Tyr Lys Cys Ser Cys Asp Pro 
                565                 570                 575     


Gly Tyr Glu Leu Ala Pro Asp Lys Arg Arg Cys Glu Ala Ala Cys Gly 
            580                 585                 590         


Gly Phe Leu Thr Lys Leu Asn Gly Ser Ile Thr Ser Pro Gly Trp Pro 
        595                 600                 605             


Lys Glu Tyr Pro Pro Asn Lys Asn Cys Ile Trp Gln Leu Val Ala Pro 
    610                 615                 620                 


Thr Gln Tyr Arg Ile Ser Leu Gln Phe Asp Phe Phe Glu Thr Glu Gly 
625                 630                 635                 640 


Asn Asp Val Cys Lys Tyr Asp Phe Val Glu Val Arg Ser Gly Leu Thr 
                645                 650                 655     


Ala Asp Ser Lys Leu His Gly Lys Phe Cys Gly Ser Glu Lys Pro Glu 
            660                 665                 670         


Val Ile Thr Ser Gln Tyr Asn Asn Met Arg Val Glu Phe Lys Ser Asp 
        675                 680                 685             


Asn Thr Val Ser Lys Lys Gly Phe Lys Ala His Phe Phe Ser Asp Lys 
    690                 695                 700                 


Asp Glu Cys Ser Lys Asp Asn Gly Gly Cys Gln Gln Asp Cys Val Asn 
705                 710                 715                 720 


Thr Phe Gly Ser Tyr Glu Cys Gln Cys Arg Ser Gly Phe Val Leu His 
                725                 730                 735     


Asp Asn Lys His Asp Cys Lys Glu Ala Gly Cys Asp His Lys Val Thr 
            740                 745                 750         


Ser Thr Ser Gly Thr Ile Thr Ser Pro Asn Trp Pro Asp Lys Tyr Pro 
        755                 760                 765             


Ser Lys Lys Glu Cys Thr Trp Ala Ile Ser Ser Thr Pro Gly His Arg 
    770                 775                 780                 


Val Lys Leu Thr Phe Met Glu Met Asp Ile Glu Ser Gln Pro Glu Cys 
785                 790                 795                 800 


Ala Tyr Asp His Leu Glu Val Phe Asp Gly Arg Asp Ala Lys Ala Pro 
                805                 810                 815     


Val Leu Gly Arg Phe Cys Gly Ser Lys Lys Pro Glu Pro Val Leu Ala 
            820                 825                 830         


Thr Gly Ser Arg Met Phe Leu Arg Phe Tyr Ser Asp Asn Ser Val Gln 
        835                 840                 845             


Arg Lys Gly Phe Gln Ala Ser His Ala Thr Glu Cys Gly Gly Gln Val 
    850                 855                 860                 


Arg Ala Asp Val Lys Thr Lys Asp Leu Tyr Ser His Ala Gln Phe Gly 
865                 870                 875                 880 


Asp Asn Asn Tyr Pro Gly Gly Val Asp Cys Glu Trp Val Ile Val Ala 
                885                 890                 895     


Glu Glu Gly Tyr Gly Val Glu Leu Val Phe Gln Thr Phe Glu Val Glu 
            900                 905                 910         


Glu Glu Thr Asp Cys Gly Tyr Asp Tyr Met Glu Leu Phe Asp Gly Tyr 
        915                 920                 925             


Asp Ser Thr Ala Pro Arg Leu Gly Arg Tyr Cys Gly Ser Gly Pro Pro 
    930                 935                 940                 


Glu Glu Val Tyr Ser Ala Gly Asp Ser Val Leu Val Lys Phe His Ser 
945                 950                 955                 960 


Asp Asp Thr Ile Thr Lys Lys Gly Phe His Leu Arg Tyr Thr Ser Thr 
                965                 970                 975     


Lys Phe Gln Asp Thr Leu His Ser Arg Lys 
            980                 985     


<210>  38
<211>  396
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  38

Met Val Ala Gly Thr Arg Cys Leu Leu Ala Leu Leu Leu Pro Gln Val 
1               5                   10                  15      


Leu Leu Gly Gly Ala Ala Gly Leu Val Pro Glu Leu Gly Arg Arg Lys 
            20                  25                  30          


Phe Ala Ala Ala Ser Ser Gly Arg Pro Ser Ser Gln Pro Ser Asp Glu 
        35                  40                  45              


Val Leu Ser Glu Phe Glu Leu Arg Leu Leu Ser Met Phe Gly Leu Lys 
    50                  55                  60                  


Gln Arg Pro Thr Pro Ser Arg Asp Ala Val Val Pro Pro Tyr Met Leu 
65                  70                  75                  80  


Asp Leu Tyr Arg Arg His Ser Gly Gln Pro Gly Ser Pro Ala Pro Asp 
                85                  90                  95      


His Arg Leu Glu Arg Ala Ala Ser Arg Ala Asn Thr Val Arg Ser Phe 
            100                 105                 110         


His His Glu Glu Ser Leu Glu Glu Leu Pro Glu Thr Ser Gly Lys Thr 
        115                 120                 125             


Thr Arg Arg Phe Phe Phe Asn Leu Ser Ser Ile Pro Thr Glu Glu Phe 
    130                 135                 140                 


Ile Thr Ser Ala Glu Leu Gln Val Phe Arg Glu Gln Met Gln Asp Ala 
145                 150                 155                 160 


Leu Gly Asn Asn Ser Ser Phe His His Arg Ile Asn Ile Tyr Glu Ile 
                165                 170                 175     


Ile Lys Pro Ala Thr Ala Asn Ser Lys Phe Pro Val Thr Arg Leu Leu 
            180                 185                 190         


Asp Thr Arg Leu Val Asn Gln Asn Ala Ser Arg Trp Glu Ser Phe Asp 
        195                 200                 205             


Val Thr Pro Ala Val Met Arg Trp Thr Ala Gln Gly His Ala Asn His 
    210                 215                 220                 


Gly Phe Val Val Glu Val Ala His Leu Glu Glu Lys Gln Gly Val Ser 
225                 230                 235                 240 


Lys Arg His Val Arg Ile Ser Arg Ser Leu His Gln Asp Glu His Ser 
                245                 250                 255     


Trp Ser Gln Ile Arg Pro Leu Leu Val Thr Phe Gly His Asp Gly Lys 
            260                 265                 270         


Gly His Pro Leu His Lys Arg Glu Lys Arg Gln Ala Lys His Lys Gln 
        275                 280                 285             


Arg Lys Arg Leu Lys Ser Ser Cys Lys Arg His Pro Leu Tyr Val Asp 
    290                 295                 300                 


Phe Ser Asp Val Gly Trp Asn Asp Trp Ile Val Ala Pro Pro Gly Tyr 
305                 310                 315                 320 


His Ala Phe Tyr Cys His Gly Glu Cys Pro Phe Pro Leu Ala Asp His 
                325                 330                 335     


Leu Asn Ser Thr Asn His Ala Ile Val Gln Thr Leu Val Asn Ser Val 
            340                 345                 350         


Asn Ser Lys Ile Pro Lys Ala Cys Cys Val Pro Thr Glu Leu Ser Ala 
        355                 360                 365             


Ile Ser Met Leu Tyr Leu Asp Glu Asn Glu Lys Val Val Leu Lys Asn 
    370                 375                 380                 


Tyr Gln Asp Met Val Val Glu Gly Cys Gly Cys Arg 
385                 390                 395     


<210>  39
<211>  408
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  39

Met Ile Pro Gly Asn Arg Met Leu Met Val Val Leu Leu Cys Gln Val 
1               5                   10                  15      


Leu Leu Gly Gly Ala Ser His Ala Ser Leu Ile Pro Glu Thr Gly Lys 
            20                  25                  30          


Lys Lys Val Ala Glu Ile Gln Gly His Ala Gly Gly Arg Arg Ser Gly 
        35                  40                  45              


Gln Ser His Glu Leu Leu Arg Asp Phe Glu Ala Thr Leu Leu Gln Met 
    50                  55                  60                  


Phe Gly Leu Arg Arg Arg Pro Gln Pro Ser Lys Ser Ala Val Ile Pro 
65                  70                  75                  80  


Asp Tyr Met Arg Asp Leu Tyr Arg Leu Gln Ser Gly Glu Glu Glu Glu 
                85                  90                  95      


Glu Gln Ile His Ser Thr Gly Leu Glu Tyr Pro Glu Arg Pro Ala Ser 
            100                 105                 110         


Arg Ala Asn Thr Val Arg Ser Phe His His Glu Glu His Leu Glu Asn 
        115                 120                 125             


Ile Pro Gly Thr Ser Glu Asn Ser Ala Phe Arg Phe Leu Phe Asn Leu 
    130                 135                 140                 


Ser Ser Ile Pro Glu Asn Glu Val Ile Ser Ser Ala Glu Leu Arg Leu 
145                 150                 155                 160 


Phe Arg Glu Gln Val Asp Gln Gly Pro Asp Trp Glu Arg Gly Phe His 
                165                 170                 175     


Arg Ile Asn Ile Tyr Glu Val Met Lys Pro Pro Ala Glu Val Val Pro 
            180                 185                 190         


Gly His Leu Ile Thr Arg Leu Leu Asp Thr Arg Leu Val His His Asn 
        195                 200                 205             


Val Thr Arg Trp Glu Thr Phe Asp Val Ser Pro Ala Val Leu Arg Trp 
    210                 215                 220                 


Thr Arg Glu Lys Gln Pro Asn Tyr Gly Leu Ala Ile Glu Val Thr His 
225                 230                 235                 240 


Leu His Gln Thr Arg Thr His Gln Gly Gln His Val Arg Ile Ser Arg 
                245                 250                 255     


Ser Leu Pro Gln Gly Ser Gly Asn Trp Ala Gln Leu Arg Pro Leu Leu 
            260                 265                 270         


Val Thr Phe Gly His Asp Gly Arg Gly His Ala Leu Thr Arg Arg Arg 
        275                 280                 285             


Arg Ala Lys Arg Ser Pro Lys His His Ser Gln Arg Ala Arg Lys Lys 
    290                 295                 300                 


Asn Lys Asn Cys Arg Arg His Ser Leu Tyr Val Asp Phe Ser Asp Val 
305                 310                 315                 320 


Gly Trp Asn Asp Trp Ile Val Ala Pro Pro Gly Tyr Gln Ala Phe Tyr 
                325                 330                 335     


Cys His Gly Asp Cys Pro Phe Pro Leu Ala Asp His Leu Asn Ser Thr 
            340                 345                 350         


Asn His Ala Ile Val Gln Thr Leu Val Asn Ser Val Asn Ser Ser Ile 
        355                 360                 365             


Pro Lys Ala Cys Cys Val Pro Thr Glu Leu Ser Ala Ile Ser Met Leu 
    370                 375                 380                 


Tyr Leu Asp Glu Tyr Asp Lys Val Val Leu Lys Asn Tyr Gln Glu Met 
385                 390                 395                 400 


Val Val Glu Gly Cys Gly Cys Arg 
                405             


<210>  40
<211>  513
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  40

Met Pro Gly Leu Gly Arg Arg Ala Gln Trp Leu Cys Trp Trp Trp Gly 
1               5                   10                  15      


Leu Leu Cys Ser Cys Cys Gly Pro Pro Pro Leu Arg Pro Pro Leu Pro 
            20                  25                  30          


Ala Ala Ala Ala Ala Ala Ala Gly Gly Gln Leu Leu Gly Asp Gly Gly 
        35                  40                  45              


Ser Pro Gly Arg Thr Glu Gln Pro Pro Pro Ser Pro Gln Ser Ser Ser 
    50                  55                  60                  


Gly Phe Leu Tyr Arg Arg Leu Lys Thr Gln Glu Lys Arg Glu Met Gln 
65                  70                  75                  80  


Lys Glu Ile Leu Ser Val Leu Gly Leu Pro His Arg Pro Arg Pro Leu 
                85                  90                  95      


His Gly Leu Gln Gln Pro Gln Pro Pro Ala Leu Arg Gln Gln Glu Glu 
            100                 105                 110         


Gln Gln Gln Gln Gln Gln Leu Pro Arg Gly Glu Pro Pro Pro Gly Arg 
        115                 120                 125             


Leu Lys Ser Ala Pro Leu Phe Met Leu Asp Leu Tyr Asn Ala Leu Ser 
    130                 135                 140                 


Ala Asp Asn Asp Glu Asp Gly Ala Ser Glu Gly Glu Arg Gln Gln Ser 
145                 150                 155                 160 


Trp Pro His Glu Ala Ala Ser Ser Ser Gln Arg Arg Gln Pro Pro Pro 
                165                 170                 175     


Gly Ala Ala His Pro Leu Asn Arg Lys Ser Leu Leu Ala Pro Gly Ser 
            180                 185                 190         


Gly Ser Gly Gly Ala Ser Pro Leu Thr Ser Ala Gln Asp Ser Ala Phe 
        195                 200                 205             


Leu Asn Asp Ala Asp Met Val Met Ser Phe Val Asn Leu Val Glu Tyr 
    210                 215                 220                 


Asp Lys Glu Phe Ser Pro Arg Gln Arg His His Lys Glu Phe Lys Phe 
225                 230                 235                 240 


Asn Leu Ser Gln Ile Pro Glu Gly Glu Val Val Thr Ala Ala Glu Phe 
                245                 250                 255     


Arg Ile Tyr Lys Asp Cys Val Met Gly Ser Phe Lys Asn Gln Thr Phe 
            260                 265                 270         


Leu Ile Ser Ile Tyr Gln Val Leu Gln Glu His Gln His Arg Asp Ser 
        275                 280                 285             


Asp Leu Phe Leu Leu Asp Thr Arg Val Val Trp Ala Ser Glu Glu Gly 
    290                 295                 300                 


Trp Leu Glu Phe Asp Ile Thr Ala Thr Ser Asn Leu Trp Val Val Thr 
305                 310                 315                 320 


Pro Gln His Asn Met Gly Leu Gln Leu Ser Val Val Thr Arg Asp Gly 
                325                 330                 335     


Val His Val His Pro Arg Ala Ala Gly Leu Val Gly Arg Asp Gly Pro 
            340                 345                 350         


Tyr Asp Lys Gln Pro Phe Met Val Ala Phe Phe Lys Val Ser Glu Val 
        355                 360                 365             


His Val Arg Thr Thr Arg Ser Ala Ser Ser Arg Arg Arg Gln Gln Ser 
    370                 375                 380                 


Arg Asn Arg Ser Thr Gln Ser Gln Asp Val Ala Arg Val Ser Ser Ala 
385                 390                 395                 400 


Ser Asp Tyr Asn Ser Ser Glu Leu Lys Thr Ala Cys Arg Lys His Glu 
                405                 410                 415     


Leu Tyr Val Ser Phe Gln Asp Leu Gly Trp Gln Asp Trp Ile Ile Ala 
            420                 425                 430         


Pro Lys Gly Tyr Ala Ala Asn Tyr Cys Asp Gly Glu Cys Ser Phe Pro 
        435                 440                 445             


Leu Asn Ala His Met Asn Ala Thr Asn His Ala Ile Val Gln Thr Leu 
    450                 455                 460                 


Val His Leu Met Asn Pro Glu Tyr Val Pro Lys Pro Cys Cys Ala Pro 
465                 470                 475                 480 


Thr Lys Leu Asn Ala Ile Ser Val Leu Tyr Phe Asp Asp Asn Ser Asn 
                485                 490                 495     


Val Ile Leu Lys Lys Tyr Arg Asn Met Val Val Arg Ala Cys Gly Cys 
            500                 505                 510         


His 
    


<210>  41
<211>  431
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  41

Met His Val Arg Ser Leu Arg Ala Ala Ala Pro His Ser Phe Val Ala 
1               5                   10                  15      


Leu Trp Ala Pro Leu Phe Leu Leu Arg Ser Ala Leu Ala Asp Phe Ser 
            20                  25                  30          


Leu Asp Asn Glu Val His Ser Ser Phe Ile His Arg Arg Leu Arg Ser 
        35                  40                  45              


Gln Glu Arg Arg Glu Met Gln Arg Glu Ile Leu Ser Ile Leu Gly Leu 
    50                  55                  60                  


Pro His Arg Pro Arg Pro His Leu Gln Gly Lys His Asn Ser Ala Pro 
65                  70                  75                  80  


Met Phe Met Leu Asp Leu Tyr Asn Ala Met Ala Val Glu Glu Gly Gly 
                85                  90                  95      


Gly Pro Gly Gly Gln Gly Phe Ser Tyr Pro Tyr Lys Ala Val Phe Ser 
            100                 105                 110         


Thr Gln Gly Pro Pro Leu Ala Ser Leu Gln Asp Ser His Phe Leu Thr 
        115                 120                 125             


Asp Ala Asp Met Val Met Ser Phe Val Asn Leu Val Glu His Asp Lys 
    130                 135                 140                 


Glu Phe Phe His Pro Arg Tyr His His Arg Glu Phe Arg Phe Asp Leu 
145                 150                 155                 160 


Ser Lys Ile Pro Glu Gly Glu Ala Val Thr Ala Ala Glu Phe Arg Ile 
                165                 170                 175     


Tyr Lys Asp Tyr Ile Arg Glu Arg Phe Asp Asn Glu Thr Phe Arg Ile 
            180                 185                 190         


Ser Val Tyr Gln Val Leu Gln Glu His Leu Gly Arg Glu Ser Asp Leu 
        195                 200                 205             


Phe Leu Leu Asp Ser Arg Thr Leu Trp Ala Ser Glu Glu Gly Trp Leu 
    210                 215                 220                 


Val Phe Asp Ile Thr Ala Thr Ser Asn His Trp Val Val Asn Pro Arg 
225                 230                 235                 240 


His Asn Leu Gly Leu Gln Leu Ser Val Glu Thr Leu Asp Gly Gln Ser 
                245                 250                 255     


Ile Asn Pro Lys Leu Ala Gly Leu Ile Gly Arg His Gly Pro Gln Asn 
            260                 265                 270         


Lys Gln Pro Phe Met Val Ala Phe Phe Lys Ala Thr Glu Val His Phe 
        275                 280                 285             


Arg Ser Ile Arg Ser Thr Gly Ser Lys Gln Arg Ser Gln Asn Arg Ser 
    290                 295                 300                 


Lys Thr Pro Lys Asn Gln Glu Ala Leu Arg Met Ala Asn Val Ala Glu 
305                 310                 315                 320 


Asn Ser Ser Ser Asp Gln Arg Gln Ala Cys Lys Lys His Glu Leu Tyr 
                325                 330                 335     


Val Ser Phe Arg Asp Leu Gly Trp Gln Asp Trp Ile Ile Ala Pro Glu 
            340                 345                 350         


Gly Tyr Ala Ala Tyr Tyr Cys Glu Gly Glu Cys Ala Phe Pro Leu Asn 
        355                 360                 365             


Ser Tyr Met Asn Ala Thr Asn His Ala Ile Val Gln Thr Leu Val His 
    370                 375                 380                 


Phe Ile Asn Pro Glu Thr Val Pro Lys Pro Cys Cys Ala Pro Thr Gln 
385                 390                 395                 400 


Leu Asn Ala Ile Ser Val Leu Tyr Phe Asp Asp Ser Ser Asn Val Ile 
                405                 410                 415     


Leu Lys Lys Tyr Arg Asn Met Val Val Arg Ala Cys Gly Cys His 
            420                 425                 430     


<210>  42
<211>  99
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  42

Met Lys Ala Ser Ala Ala Leu Leu Cys Leu Leu Leu Thr Ala Ala Ala 
1               5                   10                  15      


Phe Ser Pro Gln Gly Leu Ala Gln Pro Val Gly Ile Asn Thr Ser Thr 
            20                  25                  30          


Thr Cys Cys Tyr Arg Phe Ile Asn Lys Lys Ile Pro Lys Gln Arg Leu 
        35                  40                  45              


Glu Ser Tyr Arg Arg Thr Thr Ser Ser His Cys Pro Arg Glu Ala Val 
    50                  55                  60                  


Ile Phe Lys Thr Lys Leu Asp Lys Glu Ile Cys Ala Asp Pro Thr Gln 
65                  70                  75                  80  


Lys Trp Val Gln Asp Phe Met Lys His Leu Asp Lys Lys Thr Gln Thr 
                85                  90                  95      


Pro Lys Leu 
            


<210>  43
<211>  1207
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  43

Met Leu Leu Thr Leu Ile Ile Leu Leu Pro Val Val Ser Lys Phe Ser 
1               5                   10                  15      


Phe Val Ser Leu Ser Ala Pro Gln His Trp Ser Cys Pro Glu Gly Thr 
            20                  25                  30          


Leu Ala Gly Asn Gly Asn Ser Thr Cys Val Gly Pro Ala Pro Phe Leu 
        35                  40                  45              


Ile Phe Ser His Gly Asn Ser Ile Phe Arg Ile Asp Thr Glu Gly Thr 
    50                  55                  60                  


Asn Tyr Glu Gln Leu Val Val Asp Ala Gly Val Ser Val Ile Met Asp 
65                  70                  75                  80  


Phe His Tyr Asn Glu Lys Arg Ile Tyr Trp Val Asp Leu Glu Arg Gln 
                85                  90                  95      


Leu Leu Gln Arg Val Phe Leu Asn Gly Ser Arg Gln Glu Arg Val Cys 
            100                 105                 110         


Asn Ile Glu Lys Asn Val Ser Gly Met Ala Ile Asn Trp Ile Asn Glu 
        115                 120                 125             


Glu Val Ile Trp Ser Asn Gln Gln Glu Gly Ile Ile Thr Val Thr Asp 
    130                 135                 140                 


Met Lys Gly Asn Asn Ser His Ile Leu Leu Ser Ala Leu Lys Tyr Pro 
145                 150                 155                 160 


Ala Asn Val Ala Val Asp Pro Val Glu Arg Phe Ile Phe Trp Ser Ser 
                165                 170                 175     


Glu Val Ala Gly Ser Leu Tyr Arg Ala Asp Leu Asp Gly Val Gly Val 
            180                 185                 190         


Lys Ala Leu Leu Glu Thr Ser Glu Lys Ile Thr Ala Val Ser Leu Asp 
        195                 200                 205             


Val Leu Asp Lys Arg Leu Phe Trp Ile Gln Tyr Asn Arg Glu Gly Ser 
    210                 215                 220                 


Asn Ser Leu Ile Cys Ser Cys Asp Tyr Asp Gly Gly Ser Val His Ile 
225                 230                 235                 240 


Ser Lys His Pro Thr Gln His Asn Leu Phe Ala Met Ser Leu Phe Gly 
                245                 250                 255     


Asp Arg Ile Phe Tyr Ser Thr Trp Lys Met Lys Thr Ile Trp Ile Ala 
            260                 265                 270         


Asn Lys His Thr Gly Lys Asp Met Val Arg Ile Asn Leu His Ser Ser 
        275                 280                 285             


Phe Val Pro Leu Gly Glu Leu Lys Val Val His Pro Leu Ala Gln Pro 
    290                 295                 300                 


Lys Ala Glu Asp Asp Thr Trp Glu Pro Glu Gln Lys Leu Cys Lys Leu 
305                 310                 315                 320 


Arg Lys Gly Asn Cys Ser Ser Thr Val Cys Gly Gln Asp Leu Gln Ser 
                325                 330                 335     


His Leu Cys Met Cys Ala Glu Gly Tyr Ala Leu Ser Arg Asp Arg Lys 
            340                 345                 350         


Tyr Cys Glu Asp Val Asn Glu Cys Ala Phe Trp Asn His Gly Cys Thr 
        355                 360                 365             


Leu Gly Cys Lys Asn Thr Pro Gly Ser Tyr Tyr Cys Thr Cys Pro Val 
    370                 375                 380                 


Gly Phe Val Leu Leu Pro Asp Gly Lys Arg Cys His Gln Leu Val Ser 
385                 390                 395                 400 


Cys Pro Arg Asn Val Ser Glu Cys Ser His Asp Cys Val Leu Thr Ser 
                405                 410                 415     


Glu Gly Pro Leu Cys Phe Cys Pro Glu Gly Ser Val Leu Glu Arg Asp 
            420                 425                 430         


Gly Lys Thr Cys Ser Gly Cys Ser Ser Pro Asp Asn Gly Gly Cys Ser 
        435                 440                 445             


Gln Leu Cys Val Pro Leu Ser Pro Val Ser Trp Glu Cys Asp Cys Phe 
    450                 455                 460                 


Pro Gly Tyr Asp Leu Gln Leu Asp Glu Lys Ser Cys Ala Ala Ser Gly 
465                 470                 475                 480 


Pro Gln Pro Phe Leu Leu Phe Ala Asn Ser Gln Asp Ile Arg His Met 
                485                 490                 495     


His Phe Asp Gly Thr Asp Tyr Gly Thr Leu Leu Ser Gln Gln Met Gly 
            500                 505                 510         


Met Val Tyr Ala Leu Asp His Asp Pro Val Glu Asn Lys Ile Tyr Phe 
        515                 520                 525             


Ala His Thr Ala Leu Lys Trp Ile Glu Arg Ala Asn Met Asp Gly Ser 
    530                 535                 540                 


Gln Arg Glu Arg Leu Ile Glu Glu Gly Val Asp Val Pro Glu Gly Leu 
545                 550                 555                 560 


Ala Val Asp Trp Ile Gly Arg Arg Phe Tyr Trp Thr Asp Arg Gly Lys 
                565                 570                 575     


Ser Leu Ile Gly Arg Ser Asp Leu Asn Gly Lys Arg Ser Lys Ile Ile 
            580                 585                 590         


Thr Lys Glu Asn Ile Ser Gln Pro Arg Gly Ile Ala Val His Pro Met 
        595                 600                 605             


Ala Lys Arg Leu Phe Trp Thr Asp Thr Gly Ile Asn Pro Arg Ile Glu 
    610                 615                 620                 


Ser Ser Ser Leu Gln Gly Leu Gly Arg Leu Val Ile Ala Ser Ser Asp 
625                 630                 635                 640 


Leu Ile Trp Pro Ser Gly Ile Thr Ile Asp Phe Leu Thr Asp Lys Leu 
                645                 650                 655     


Tyr Trp Cys Asp Ala Lys Gln Ser Val Ile Glu Met Ala Asn Leu Asp 
            660                 665                 670         


Gly Ser Lys Arg Arg Arg Leu Thr Gln Asn Asp Val Gly His Pro Phe 
        675                 680                 685             


Ala Val Ala Val Phe Glu Asp Tyr Val Trp Phe Ser Asp Trp Ala Met 
    690                 695                 700                 


Pro Ser Val Met Arg Val Asn Lys Arg Thr Gly Lys Asp Arg Val Arg 
705                 710                 715                 720 


Leu Gln Gly Ser Met Leu Lys Pro Ser Ser Leu Val Val Val His Pro 
                725                 730                 735     


Leu Ala Lys Pro Gly Ala Asp Pro Cys Leu Tyr Gln Asn Gly Gly Cys 
            740                 745                 750         


Glu His Ile Cys Lys Lys Arg Leu Gly Thr Ala Trp Cys Ser Cys Arg 
        755                 760                 765             


Glu Gly Phe Met Lys Ala Ser Asp Gly Lys Thr Cys Leu Ala Leu Asp 
    770                 775                 780                 


Gly His Gln Leu Leu Ala Gly Gly Glu Val Asp Leu Lys Asn Gln Val 
785                 790                 795                 800 


Thr Pro Leu Asp Ile Leu Ser Lys Thr Arg Val Ser Glu Asp Asn Ile 
                805                 810                 815     


Thr Glu Ser Gln His Met Leu Val Ala Glu Ile Met Val Ser Asp Gln 
            820                 825                 830         


Asp Asp Cys Ala Pro Val Gly Cys Ser Met Tyr Ala Arg Cys Ile Ser 
        835                 840                 845             


Glu Gly Glu Asp Ala Thr Cys Gln Cys Leu Lys Gly Phe Ala Gly Asp 
    850                 855                 860                 


Gly Lys Leu Cys Ser Asp Ile Asp Glu Cys Glu Met Gly Val Pro Val 
865                 870                 875                 880 


Cys Pro Pro Ala Ser Ser Lys Cys Ile Asn Thr Glu Gly Gly Tyr Val 
                885                 890                 895     


Cys Arg Cys Ser Glu Gly Tyr Gln Gly Asp Gly Ile His Cys Leu Asp 
            900                 905                 910         


Ile Asp Glu Cys Gln Leu Gly Glu His Ser Cys Gly Glu Asn Ala Ser 
        915                 920                 925             


Cys Thr Asn Thr Glu Gly Gly Tyr Thr Cys Met Cys Ala Gly Arg Leu 
    930                 935                 940                 


Ser Glu Pro Gly Leu Ile Cys Pro Asp Ser Thr Pro Pro Pro His Leu 
945                 950                 955                 960 


Arg Glu Asp Asp His His Tyr Ser Val Arg Asn Ser Asp Ser Glu Cys 
                965                 970                 975     


Pro Leu Ser His Asp Gly Tyr Cys Leu His Asp Gly Val Cys Met Tyr 
            980                 985                 990         


Ile Glu Ala Leu Asp Lys Tyr Ala  Cys Asn Cys Val Val  Gly Tyr Ile 
        995                 1000                 1005             


Gly Glu  Arg Cys Gln Tyr Arg  Asp Leu Lys Trp Trp  Glu Leu Arg 
    1010                 1015                 1020             


His Ala  Gly His Gly Gln Gln  Gln Lys Val Ile Val  Val Ala Val 
    1025                 1030                 1035             


Cys Val  Val Val Leu Val Met  Leu Leu Leu Leu Ser  Leu Trp Gly 
    1040                 1045                 1050             


Ala His  Tyr Tyr Arg Thr Gln  Lys Leu Leu Ser Lys  Asn Pro Lys 
    1055                 1060                 1065             


Asn Pro  Tyr Glu Glu Ser Ser  Arg Asp Val Arg Ser  Arg Arg Pro 
    1070                 1075                 1080             


Ala Asp  Thr Glu Asp Gly Met  Ser Ser Cys Pro Gln  Pro Trp Phe 
    1085                 1090                 1095             


Val Val  Ile Lys Glu His Gln  Asp Leu Lys Asn Gly  Gly Gln Pro 
    1100                 1105                 1110             


Val Ala  Gly Glu Asp Gly Gln  Ala Ala Asp Gly Ser  Met Gln Pro 
    1115                 1120                 1125             


Thr Ser  Trp Arg Gln Glu Pro  Gln Leu Cys Gly Met  Gly Thr Glu 
    1130                 1135                 1140             


Gln Gly  Cys Trp Ile Pro Val  Ser Ser Asp Lys Gly  Ser Cys Pro 
    1145                 1150                 1155             


Gln Val  Met Glu Arg Ser Phe  His Met Pro Ser Tyr  Gly Thr Gln 
    1160                 1165                 1170             


Thr Leu  Glu Gly Gly Val Glu  Lys Pro His Ser Leu  Leu Ser Ala 
    1175                 1180                 1185             


Asn Pro  Leu Trp Gln Gln Arg  Ala Leu Asp Pro Pro  His Gln Met 
    1190                 1195                 1200             


Glu Leu  Thr Gln 
    1205         


<210>  44
<211>  169
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  44

Met Thr Ala Gly Arg Arg Met Glu Met Leu Cys Ala Gly Arg Val Pro 
1               5                   10                  15      


Ala Leu Leu Leu Cys Leu Gly Phe His Leu Leu Gln Ala Val Leu Ser 
            20                  25                  30          


Thr Thr Val Ile Pro Ser Cys Ile Pro Gly Glu Ser Ser Asp Asn Cys 
        35                  40                  45              


Thr Ala Leu Val Gln Thr Glu Asp Asn Pro Arg Val Ala Gln Val Ser 
    50                  55                  60                  


Ile Thr Lys Cys Ser Ser Asp Met Asn Gly Tyr Cys Leu His Gly Gln 
65                  70                  75                  80  


Cys Ile Tyr Leu Val Asp Met Ser Gln Asn Tyr Cys Arg Cys Glu Val 
                85                  90                  95      


Gly Tyr Thr Gly Val Arg Cys Glu His Phe Phe Leu Thr Val His Gln 
            100                 105                 110         


Pro Leu Ser Lys Glu Tyr Val Ala Leu Thr Val Ile Leu Ile Ile Leu 
        115                 120                 125             


Phe Leu Ile Thr Val Val Gly Ser Thr Tyr Tyr Phe Cys Arg Trp Tyr 
    130                 135                 140                 


Arg Asn Arg Lys Ser Lys Glu Pro Lys Lys Glu Tyr Glu Arg Val Thr 
145                 150                 155                 160 


Ser Gly Asp Pro Glu Leu Pro Gln Val 
                165                 


<210>  45
<211>  155
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  45

Met Ala Glu Gly Glu Ile Thr Thr Phe Thr Ala Leu Thr Glu Lys Phe 
1               5                   10                  15      


Asn Leu Pro Pro Gly Asn Tyr Lys Lys Pro Lys Leu Leu Tyr Cys Ser 
            20                  25                  30          


Asn Gly Gly His Phe Leu Arg Ile Leu Pro Asp Gly Thr Val Asp Gly 
        35                  40                  45              


Thr Arg Asp Arg Ser Asp Gln His Ile Gln Leu Gln Leu Ser Ala Glu 
    50                  55                  60                  


Ser Val Gly Glu Val Tyr Ile Lys Ser Thr Glu Thr Gly Gln Tyr Leu 
65                  70                  75                  80  


Ala Met Asp Thr Asp Gly Leu Leu Tyr Gly Ser Gln Thr Pro Asn Glu 
                85                  90                  95      


Glu Cys Leu Phe Leu Glu Arg Leu Glu Glu Asn His Tyr Asn Thr Tyr 
            100                 105                 110         


Ile Ser Lys Lys His Ala Glu Lys Asn Trp Phe Val Gly Leu Lys Lys 
        115                 120                 125             


Asn Gly Ser Cys Lys Arg Gly Pro Arg Thr His Tyr Gly Gln Lys Ala 
    130                 135                 140                 


Ile Leu Phe Leu Pro Leu Pro Val Ser Ser Asp 
145                 150                 155 


<210>  46
<211>  288
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  46

Met Val Gly Val Gly Gly Gly Asp Val Glu Asp Val Thr Pro Arg Pro 
1               5                   10                  15      


Gly Gly Cys Gln Ile Ser Gly Arg Gly Ala Arg Gly Cys Asn Gly Ile 
            20                  25                  30          


Pro Gly Ala Ala Ala Trp Glu Ala Ala Leu Pro Arg Arg Arg Pro Arg 
        35                  40                  45              


Arg His Pro Ser Val Asn Pro Arg Ser Arg Ala Ala Gly Ser Pro Arg 
    50                  55                  60                  


Thr Arg Gly Arg Arg Thr Glu Glu Arg Pro Ser Gly Ser Arg Leu Gly 
65                  70                  75                  80  


Asp Arg Gly Arg Gly Arg Ala Leu Pro Gly Gly Arg Leu Gly Gly Arg 
                85                  90                  95      


Gly Arg Gly Arg Ala Pro Glu Arg Val Gly Gly Arg Gly Arg Gly Arg 
            100                 105                 110         


Gly Thr Ala Ala Pro Arg Ala Ala Pro Ala Ala Arg Gly Ser Arg Pro 
        115                 120                 125             


Gly Pro Ala Gly Thr Met Ala Ala Gly Ser Ile Thr Thr Leu Pro Ala 
    130                 135                 140                 


Leu Pro Glu Asp Gly Gly Ser Gly Ala Phe Pro Pro Gly His Phe Lys 
145                 150                 155                 160 


Asp Pro Lys Arg Leu Tyr Cys Lys Asn Gly Gly Phe Phe Leu Arg Ile 
                165                 170                 175     


His Pro Asp Gly Arg Val Asp Gly Val Arg Glu Lys Ser Asp Pro His 
            180                 185                 190         


Ile Lys Leu Gln Leu Gln Ala Glu Glu Arg Gly Val Val Ser Ile Lys 
        195                 200                 205             


Gly Val Cys Ala Asn Arg Tyr Leu Ala Met Lys Glu Asp Gly Arg Leu 
    210                 215                 220                 


Leu Ala Ser Lys Cys Val Thr Asp Glu Cys Phe Phe Phe Glu Arg Leu 
225                 230                 235                 240 


Glu Ser Asn Asn Tyr Asn Thr Tyr Arg Ser Arg Lys Tyr Thr Ser Trp 
                245                 250                 255     


Tyr Val Ala Leu Lys Arg Thr Gly Gln Tyr Lys Leu Gly Ser Lys Thr 
            260                 265                 270         


Gly Pro Gly Gln Lys Ala Ile Leu Phe Leu Pro Met Ser Ala Lys Ser 
        275                 280                 285             


<210>  47
<211>  194
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  47

Met His Lys Trp Ile Leu Thr Trp Ile Leu Pro Thr Leu Leu Tyr Arg 
1               5                   10                  15      


Ser Cys Phe His Ile Ile Cys Leu Val Gly Thr Ile Ser Leu Ala Cys 
            20                  25                  30          


Asn Asp Met Thr Pro Glu Gln Met Ala Thr Asn Val Asn Cys Ser Ser 
        35                  40                  45              


Pro Glu Arg His Thr Arg Ser Tyr Asp Tyr Met Glu Gly Gly Asp Ile 
    50                  55                  60                  


Arg Val Arg Arg Leu Phe Cys Arg Thr Gln Trp Tyr Leu Arg Ile Asp 
65                  70                  75                  80  


Lys Arg Gly Lys Val Lys Gly Thr Gln Glu Met Lys Asn Asn Tyr Asn 
                85                  90                  95      


Ile Met Glu Ile Arg Thr Val Ala Val Gly Ile Val Ala Ile Lys Gly 
            100                 105                 110         


Val Glu Ser Glu Phe Tyr Leu Ala Met Asn Lys Glu Gly Lys Leu Tyr 
        115                 120                 125             


Ala Lys Lys Glu Cys Asn Glu Asp Cys Asn Phe Lys Glu Leu Ile Leu 
    130                 135                 140                 


Glu Asn His Tyr Asn Thr Tyr Ala Ser Ala Lys Trp Thr His Asn Gly 
145                 150                 155                 160 


Gly Glu Met Phe Val Ala Leu Asn Gln Lys Gly Ile Pro Val Arg Gly 
                165                 170                 175     


Lys Lys Thr Lys Lys Glu Gln Lys Thr Ala His Phe Leu Pro Met Ala 
            180                 185                 190         


Ile Thr 
        


<210>  48
<211>  208
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  48

Met Lys Leu Leu Pro Ser Val Val Leu Lys Leu Phe Leu Ala Ala Val 
1               5                   10                  15      


Leu Ser Ala Leu Val Thr Gly Glu Ser Leu Glu Arg Leu Arg Arg Gly 
            20                  25                  30          


Leu Ala Ala Gly Thr Ser Asn Pro Asp Pro Pro Thr Val Ser Thr Asp 
        35                  40                  45              


Gln Leu Leu Pro Leu Gly Gly Gly Arg Asp Arg Lys Val Arg Asp Leu 
    50                  55                  60                  


Gln Glu Ala Asp Leu Asp Leu Leu Arg Val Thr Leu Ser Ser Lys Pro 
65                  70                  75                  80  


Gln Ala Leu Ala Thr Pro Asn Lys Glu Glu His Gly Lys Arg Lys Lys 
                85                  90                  95      


Lys Gly Lys Gly Leu Gly Lys Lys Arg Asp Pro Cys Leu Arg Lys Tyr 
            100                 105                 110         


Lys Asp Phe Cys Ile His Gly Glu Cys Lys Tyr Val Lys Glu Leu Arg 
        115                 120                 125             


Ala Pro Ser Cys Ile Cys His Pro Gly Tyr His Gly Glu Arg Cys His 
    130                 135                 140                 


Gly Leu Ser Leu Pro Val Glu Asn Arg Leu Tyr Thr Tyr Asp His Thr 
145                 150                 155                 160 


Thr Ile Leu Ala Val Val Ala Val Val Leu Ser Ser Val Cys Leu Leu 
                165                 170                 175     


Val Ile Val Gly Leu Leu Met Phe Arg Tyr His Arg Arg Gly Gly Tyr 
            180                 185                 190         


Asp Val Glu Asn Glu Glu Lys Val Lys Leu Gly Met Thr Asn Ser His 
        195                 200                 205             


<210>  49
<211>  728
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  49

Met Trp Val Thr Lys Leu Leu Pro Ala Leu Leu Leu Gln His Val Leu 
1               5                   10                  15      


Leu His Leu Leu Leu Leu Pro Ile Ala Ile Pro Tyr Ala Glu Gly Gln 
            20                  25                  30          


Arg Lys Arg Arg Asn Thr Ile His Glu Phe Lys Lys Ser Ala Lys Thr 
        35                  40                  45              


Thr Leu Ile Lys Ile Asp Pro Ala Leu Lys Ile Lys Thr Lys Lys Val 
    50                  55                  60                  


Asn Thr Ala Asp Gln Cys Ala Asn Arg Cys Thr Arg Asn Lys Gly Leu 
65                  70                  75                  80  


Pro Phe Thr Cys Lys Ala Phe Val Phe Asp Lys Ala Arg Lys Gln Cys 
                85                  90                  95      


Leu Trp Phe Pro Phe Asn Ser Met Ser Ser Gly Val Lys Lys Glu Phe 
            100                 105                 110         


Gly His Glu Phe Asp Leu Tyr Glu Asn Lys Asp Tyr Ile Arg Asn Cys 
        115                 120                 125             


Ile Ile Gly Lys Gly Arg Ser Tyr Lys Gly Thr Val Ser Ile Thr Lys 
    130                 135                 140                 


Ser Gly Ile Lys Cys Gln Pro Trp Ser Ser Met Ile Pro His Glu His 
145                 150                 155                 160 


Ser Phe Leu Pro Ser Ser Tyr Arg Gly Lys Asp Leu Gln Glu Asn Tyr 
                165                 170                 175     


Cys Arg Asn Pro Arg Gly Glu Glu Gly Gly Pro Trp Cys Phe Thr Ser 
            180                 185                 190         


Asn Pro Glu Val Arg Tyr Glu Val Cys Asp Ile Pro Gln Cys Ser Glu 
        195                 200                 205             


Val Glu Cys Met Thr Cys Asn Gly Glu Ser Tyr Arg Gly Leu Met Asp 
    210                 215                 220                 


His Thr Glu Ser Gly Lys Ile Cys Gln Arg Trp Asp His Gln Thr Pro 
225                 230                 235                 240 


His Arg His Lys Phe Leu Pro Glu Arg Tyr Pro Asp Lys Gly Phe Asp 
                245                 250                 255     


Asp Asn Tyr Cys Arg Asn Pro Asp Gly Gln Pro Arg Pro Trp Cys Tyr 
            260                 265                 270         


Thr Leu Asp Pro His Thr Arg Trp Glu Tyr Cys Ala Ile Lys Thr Cys 
        275                 280                 285             


Ala Asp Asn Thr Met Asn Asp Thr Asp Val Pro Leu Glu Thr Thr Glu 
    290                 295                 300                 


Cys Ile Gln Gly Gln Gly Glu Gly Tyr Arg Gly Thr Val Asn Thr Ile 
305                 310                 315                 320 


Trp Asn Gly Ile Pro Cys Gln Arg Trp Asp Ser Gln Tyr Pro His Glu 
                325                 330                 335     


His Asp Met Thr Pro Glu Asn Phe Lys Cys Lys Asp Leu Arg Glu Asn 
            340                 345                 350         


Tyr Cys Arg Asn Pro Asp Gly Ser Glu Ser Pro Trp Cys Phe Thr Thr 
        355                 360                 365             


Asp Pro Asn Ile Arg Val Gly Tyr Cys Ser Gln Ile Pro Asn Cys Asp 
    370                 375                 380                 


Met Ser His Gly Gln Asp Cys Tyr Arg Gly Asn Gly Lys Asn Tyr Met 
385                 390                 395                 400 


Gly Asn Leu Ser Gln Thr Arg Ser Gly Leu Thr Cys Ser Met Trp Asp 
                405                 410                 415     


Lys Asn Met Glu Asp Leu His Arg His Ile Phe Trp Glu Pro Asp Ala 
            420                 425                 430         


Ser Lys Leu Asn Glu Asn Tyr Cys Arg Asn Pro Asp Asp Asp Ala His 
        435                 440                 445             


Gly Pro Trp Cys Tyr Thr Gly Asn Pro Leu Ile Pro Trp Asp Tyr Cys 
    450                 455                 460                 


Pro Ile Ser Arg Cys Glu Gly Asp Thr Thr Pro Thr Ile Val Asn Leu 
465                 470                 475                 480 


Asp His Pro Val Ile Ser Cys Ala Lys Thr Lys Gln Leu Arg Val Val 
                485                 490                 495     


Asn Gly Ile Pro Thr Arg Thr Asn Ile Gly Trp Met Val Ser Leu Arg 
            500                 505                 510         


Tyr Arg Asn Lys His Ile Cys Gly Gly Ser Leu Ile Lys Glu Ser Trp 
        515                 520                 525             


Val Leu Thr Ala Arg Gln Cys Phe Pro Ser Arg Asp Leu Lys Asp Tyr 
    530                 535                 540                 


Glu Ala Trp Leu Gly Ile His Asp Val His Gly Arg Gly Asp Glu Lys 
545                 550                 555                 560 


Cys Lys Gln Val Leu Asn Val Ser Gln Leu Val Tyr Gly Pro Glu Gly 
                565                 570                 575     


Ser Asp Leu Val Leu Met Lys Leu Ala Arg Pro Ala Val Leu Asp Asp 
            580                 585                 590         


Phe Val Ser Thr Ile Asp Leu Pro Asn Tyr Gly Cys Thr Ile Pro Glu 
        595                 600                 605             


Lys Thr Ser Cys Ser Val Tyr Gly Trp Gly Tyr Thr Gly Leu Ile Asn 
    610                 615                 620                 


Tyr Asp Gly Leu Leu Arg Val Ala His Leu Tyr Ile Met Gly Asn Glu 
625                 630                 635                 640 


Lys Cys Ser Gln His His Arg Gly Lys Val Thr Leu Asn Glu Ser Glu 
                645                 650                 655     


Ile Cys Ala Gly Ala Glu Lys Ile Gly Ser Gly Pro Cys Glu Gly Asp 
            660                 665                 670         


Tyr Gly Gly Pro Leu Val Cys Glu Gln His Lys Met Arg Met Val Leu 
        675                 680                 685             


Gly Val Ile Val Pro Gly Arg Gly Cys Ala Ile Pro Asn Arg Pro Gly 
    690                 695                 700                 


Ile Phe Val Arg Val Ala Tyr Tyr Ala Lys Trp Ile His Lys Ile Ile 
705                 710                 715                 720 


Leu Thr Tyr Lys Val Pro Gln Ser 
                725             


<210>  50
<211>  641
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  50

Met Ala Lys Ala Ala Ala Ile Gly Ile Asp Leu Gly Thr Thr Tyr Ser 
1               5                   10                  15      


Cys Val Gly Val Phe Gln His Gly Lys Val Glu Ile Ile Ala Asn Asp 
            20                  25                  30          


Gln Gly Asn Arg Thr Thr Pro Ser Tyr Val Ala Phe Thr Asp Thr Glu 
        35                  40                  45              


Arg Leu Ile Gly Asp Ala Ala Lys Asn Gln Val Ala Leu Asn Pro Gln 
    50                  55                  60                  


Asn Thr Val Phe Asp Ala Lys Arg Leu Ile Gly Arg Lys Phe Gly Asp 
65                  70                  75                  80  


Pro Val Val Gln Ser Asp Met Lys His Trp Pro Phe Gln Val Ile Asn 
                85                  90                  95      


Asp Gly Asp Lys Pro Lys Val Gln Val Ser Tyr Lys Gly Glu Thr Lys 
            100                 105                 110         


Ala Phe Tyr Pro Glu Glu Ile Ser Ser Met Val Leu Thr Lys Met Lys 
        115                 120                 125             


Glu Ile Ala Glu Ala Tyr Leu Gly Tyr Pro Val Thr Asn Ala Val Ile 
    130                 135                 140                 


Thr Val Pro Ala Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr Lys Asp 
145                 150                 155                 160 


Ala Gly Val Ile Ala Gly Leu Asn Val Leu Arg Ile Ile Asn Glu Pro 
                165                 170                 175     


Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Arg Thr Gly Lys Gly Glu 
            180                 185                 190         


Arg Asn Val Leu Ile Phe Asp Leu Gly Gly Gly Thr Phe Asp Val Ser 
        195                 200                 205             


Ile Leu Thr Ile Asp Asp Gly Ile Phe Glu Val Lys Ala Thr Ala Gly 
    210                 215                 220                 


Asp Thr His Leu Gly Gly Glu Asp Phe Asp Asn Arg Leu Val Asn His 
225                 230                 235                 240 


Phe Val Glu Glu Phe Lys Arg Lys His Lys Lys Asp Ile Ser Gln Asn 
                245                 250                 255     


Lys Arg Ala Val Arg Arg Leu Arg Thr Ala Cys Glu Arg Ala Lys Arg 
            260                 265                 270         


Thr Leu Ser Ser Ser Thr Gln Ala Ser Leu Glu Ile Asp Ser Leu Phe 
        275                 280                 285             


Glu Gly Ile Asp Phe Tyr Thr Ser Ile Thr Arg Ala Arg Phe Glu Glu 
    290                 295                 300                 


Leu Cys Ser Asp Leu Phe Arg Ser Thr Leu Glu Pro Val Glu Lys Ala 
305                 310                 315                 320 


Leu Arg Asp Ala Lys Leu Asp Lys Ala Gln Ile His Asp Leu Val Leu 
                325                 330                 335     


Val Gly Gly Ser Thr Arg Ile Pro Lys Val Gln Lys Leu Leu Gln Asp 
            340                 345                 350         


Phe Phe Asn Gly Arg Asp Leu Asn Lys Ser Ile Asn Pro Asp Glu Ala 
        355                 360                 365             


Val Ala Tyr Gly Ala Ala Val Gln Ala Ala Ile Leu Met Gly Asp Lys 
    370                 375                 380                 


Ser Glu Asn Val Gln Asp Leu Leu Leu Leu Asp Val Ala Pro Leu Ser 
385                 390                 395                 400 


Leu Gly Leu Glu Thr Ala Gly Gly Val Met Thr Ala Leu Ile Lys Arg 
                405                 410                 415     


Asn Ser Thr Ile Pro Thr Lys Gln Thr Gln Ile Phe Thr Thr Tyr Ser 
            420                 425                 430         


Asp Asn Gln Pro Gly Val Leu Ile Gln Val Tyr Glu Gly Glu Arg Ala 
        435                 440                 445             


Met Thr Lys Asp Asn Asn Leu Leu Gly Arg Phe Glu Leu Ser Gly Ile 
    450                 455                 460                 


Pro Pro Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr Phe Asp Ile 
465                 470                 475                 480 


Asp Ala Asn Gly Ile Leu Asn Val Thr Ala Thr Asp Lys Ser Thr Gly 
                485                 490                 495     


Lys Ala Asn Lys Ile Thr Ile Thr Asn Asp Lys Gly Arg Leu Ser Lys 
            500                 505                 510         


Glu Glu Ile Glu Arg Met Val Gln Glu Ala Glu Lys Tyr Lys Ala Glu 
        515                 520                 525             


Asp Glu Val Gln Arg Glu Arg Val Ser Ala Lys Asn Ala Leu Glu Ser 
    530                 535                 540                 


Tyr Ala Phe Asn Met Lys Ser Ala Val Glu Asp Glu Gly Leu Lys Gly 
545                 550                 555                 560 


Lys Ile Ser Glu Ala Asp Lys Lys Lys Val Leu Asp Lys Cys Gln Glu 
                565                 570                 575     


Val Ile Ser Trp Leu Asp Ala Asn Thr Leu Ala Glu Lys Asp Glu Phe 
            580                 585                 590         


Glu His Lys Arg Lys Glu Leu Glu Gln Val Cys Asn Pro Ile Ile Ser 
        595                 600                 605             


Gly Leu Tyr Gln Gly Ala Gly Gly Pro Gly Pro Gly Gly Phe Gly Ala 
    610                 615                 620                 


Gln Gly Pro Lys Gly Gly Ser Gly Ser Gly Pro Thr Ile Glu Glu Val 
625                 630                 635                 640 


Asp 
    


<210>  51
<211>  641
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  51

Met Ala Lys Ala Ala Ala Ile Gly Ile Asp Leu Gly Thr Thr Tyr Ser 
1               5                   10                  15      


Cys Val Gly Val Phe Gln His Gly Lys Val Glu Ile Ile Ala Asn Asp 
            20                  25                  30          


Gln Gly Asn Arg Thr Thr Pro Ser Tyr Val Ala Phe Thr Asp Thr Glu 
        35                  40                  45              


Arg Leu Ile Gly Asp Ala Ala Lys Asn Gln Val Ala Leu Asn Pro Gln 
    50                  55                  60                  


Asn Thr Val Phe Asp Ala Lys Arg Leu Ile Gly Arg Lys Phe Gly Asp 
65                  70                  75                  80  


Pro Val Val Gln Ser Asp Met Lys His Trp Pro Phe Gln Val Ile Asn 
                85                  90                  95      


Asp Gly Asp Lys Pro Lys Val Gln Val Ser Tyr Lys Gly Glu Thr Lys 
            100                 105                 110         


Ala Phe Tyr Pro Glu Glu Ile Ser Ser Met Val Leu Thr Lys Met Lys 
        115                 120                 125             


Glu Ile Ala Glu Ala Tyr Leu Gly Tyr Pro Val Thr Asn Ala Val Ile 
    130                 135                 140                 


Thr Val Pro Ala Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr Lys Asp 
145                 150                 155                 160 


Ala Gly Val Ile Ala Gly Leu Asn Val Leu Arg Ile Ile Asn Glu Pro 
                165                 170                 175     


Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Arg Thr Gly Lys Gly Glu 
            180                 185                 190         


Arg Asn Val Leu Ile Phe Asp Leu Gly Gly Gly Thr Phe Asp Val Ser 
        195                 200                 205             


Ile Leu Thr Ile Asp Asp Gly Ile Phe Glu Val Lys Ala Thr Ala Gly 
    210                 215                 220                 


Asp Thr His Leu Gly Gly Glu Asp Phe Asp Asn Arg Leu Val Asn His 
225                 230                 235                 240 


Phe Val Glu Glu Phe Lys Arg Lys His Lys Lys Asp Ile Ser Gln Asn 
                245                 250                 255     


Lys Arg Ala Val Arg Arg Leu Arg Thr Ala Cys Glu Arg Ala Lys Arg 
            260                 265                 270         


Thr Leu Ser Ser Ser Thr Gln Ala Ser Leu Glu Ile Asp Ser Leu Phe 
        275                 280                 285             


Glu Gly Ile Asp Phe Tyr Thr Ser Ile Thr Arg Ala Arg Phe Glu Glu 
    290                 295                 300                 


Leu Cys Ser Asp Leu Phe Arg Ser Thr Leu Glu Pro Val Glu Lys Ala 
305                 310                 315                 320 


Leu Arg Asp Ala Lys Leu Asp Lys Ala Gln Ile His Asp Leu Val Leu 
                325                 330                 335     


Val Gly Gly Ser Thr Arg Ile Pro Lys Val Gln Lys Leu Leu Gln Asp 
            340                 345                 350         


Phe Phe Asn Gly Arg Asp Leu Asn Lys Ser Ile Asn Pro Asp Glu Ala 
        355                 360                 365             


Val Ala Tyr Gly Ala Ala Val Gln Ala Ala Ile Leu Met Gly Asp Lys 
    370                 375                 380                 


Ser Glu Asn Val Gln Asp Leu Leu Leu Leu Asp Val Ala Pro Leu Ser 
385                 390                 395                 400 


Leu Gly Leu Glu Thr Ala Gly Gly Val Met Thr Ala Leu Ile Lys Arg 
                405                 410                 415     


Asn Ser Thr Ile Pro Thr Lys Gln Thr Gln Ile Phe Thr Thr Tyr Ser 
            420                 425                 430         


Asp Asn Gln Pro Gly Val Leu Ile Gln Val Tyr Glu Gly Glu Arg Ala 
        435                 440                 445             


Met Thr Lys Asp Asn Asn Leu Leu Gly Arg Phe Glu Leu Ser Gly Ile 
    450                 455                 460                 


Pro Pro Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr Phe Asp Ile 
465                 470                 475                 480 


Asp Ala Asn Gly Ile Leu Asn Val Thr Ala Thr Asp Lys Ser Thr Gly 
                485                 490                 495     


Lys Ala Asn Lys Ile Thr Ile Thr Asn Asp Lys Gly Arg Leu Ser Lys 
            500                 505                 510         


Glu Glu Ile Glu Arg Met Val Gln Glu Ala Glu Lys Tyr Lys Ala Glu 
        515                 520                 525             


Asp Glu Val Gln Arg Glu Arg Val Ser Ala Lys Asn Ala Leu Glu Ser 
    530                 535                 540                 


Tyr Ala Phe Asn Met Lys Ser Ala Val Glu Asp Glu Gly Leu Lys Gly 
545                 550                 555                 560 


Lys Ile Ser Glu Ala Asp Lys Lys Lys Val Leu Asp Lys Cys Gln Glu 
                565                 570                 575     


Val Ile Ser Trp Leu Asp Ala Asn Thr Leu Ala Glu Lys Asp Glu Phe 
            580                 585                 590         


Glu His Lys Arg Lys Glu Leu Glu Gln Val Cys Asn Pro Ile Ile Ser 
        595                 600                 605             


Gly Leu Tyr Gln Gly Ala Gly Gly Pro Gly Pro Gly Gly Phe Gly Ala 
    610                 615                 620                 


Gln Gly Pro Lys Gly Gly Ser Gly Ser Gly Pro Thr Ile Glu Glu Val 
625                 630                 635                 640 


Asp 
    


<210>  52
<211>  641
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  52

Met Ala Thr Ala Lys Gly Ile Ala Ile Gly Ile Asp Leu Gly Thr Thr 
1               5                   10                  15      


Tyr Ser Cys Val Gly Val Phe Gln His Gly Lys Val Glu Ile Ile Ala 
            20                  25                  30          


Asn Asp Gln Gly Asn Arg Thr Thr Pro Ser Tyr Val Ala Phe Thr Asp 
        35                  40                  45              


Thr Glu Arg Leu Ile Gly Asp Ala Ala Lys Asn Gln Val Ala Met Asn 
    50                  55                  60                  


Pro Gln Asn Thr Val Phe Asp Ala Lys Arg Leu Ile Gly Arg Lys Phe 
65                  70                  75                  80  


Asn Asp Pro Val Val Gln Ala Asp Met Lys Leu Trp Pro Phe Gln Val 
                85                  90                  95      


Ile Asn Glu Gly Gly Lys Pro Lys Val Leu Val Ser Tyr Lys Gly Glu 
            100                 105                 110         


Asn Lys Ala Phe Tyr Pro Glu Glu Ile Ser Ser Met Val Leu Thr Lys 
        115                 120                 125             


Leu Lys Glu Thr Ala Glu Ala Phe Leu Gly His Pro Val Thr Asn Ala 
    130                 135                 140                 


Val Ile Thr Val Pro Ala Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr 
145                 150                 155                 160 


Lys Asp Ala Gly Val Ile Ala Gly Leu Asn Val Leu Arg Ile Ile Asn 
                165                 170                 175     


Glu Pro Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Lys Gly Gly Gln 
            180                 185                 190         


Gly Glu Arg His Val Leu Ile Phe Asp Leu Gly Gly Gly Thr Phe Asp 
        195                 200                 205             


Val Ser Ile Leu Thr Ile Asp Asp Gly Ile Phe Glu Val Lys Ala Thr 
    210                 215                 220                 


Ala Gly Asp Thr His Leu Gly Gly Glu Asp Phe Asp Asn Arg Leu Val 
225                 230                 235                 240 


Ser His Phe Val Glu Glu Phe Lys Arg Lys His Lys Lys Asp Ile Ser 
                245                 250                 255     


Gln Asn Lys Arg Ala Val Arg Arg Leu Arg Thr Ala Cys Glu Arg Ala 
            260                 265                 270         


Lys Arg Thr Leu Ser Ser Ser Thr Gln Ala Asn Leu Glu Ile Asp Ser 
        275                 280                 285             


Leu Tyr Glu Gly Ile Asp Phe Tyr Thr Ser Ile Thr Arg Ala Arg Phe 
    290                 295                 300                 


Glu Glu Leu Cys Ala Asp Leu Phe Arg Gly Thr Leu Glu Pro Val Glu 
305                 310                 315                 320 


Lys Ala Leu Arg Asp Ala Lys Met Asp Lys Ala Lys Ile His Asp Ile 
                325                 330                 335     


Val Leu Val Gly Gly Ser Thr Arg Ile Pro Lys Val Gln Arg Leu Leu 
            340                 345                 350         


Gln Asp Tyr Phe Asn Gly Arg Asp Leu Asn Lys Ser Ile Asn Pro Asp 
        355                 360                 365             


Glu Ala Val Ala Tyr Gly Ala Ala Val Gln Ala Ala Ile Leu Met Gly 
    370                 375                 380                 


Asp Lys Ser Glu Lys Val Gln Asp Leu Leu Leu Leu Asp Val Ala Pro 
385                 390                 395                 400 


Leu Ser Leu Gly Leu Glu Thr Ala Gly Gly Val Met Thr Ala Leu Ile 
                405                 410                 415     


Lys Arg Asn Ser Thr Ile Pro Thr Lys Gln Thr Gln Ile Phe Thr Thr 
            420                 425                 430         


Tyr Ser Asp Asn Gln Pro Gly Val Leu Ile Gln Val Tyr Glu Gly Glu 
        435                 440                 445             


Arg Ala Met Thr Lys Asp Asn Asn Leu Leu Gly Arg Phe Asp Leu Thr 
    450                 455                 460                 


Gly Ile Pro Pro Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr Phe 
465                 470                 475                 480 


Asp Ile Asp Ala Asn Gly Ile Leu Asn Val Thr Ala Thr Asp Lys Ser 
                485                 490                 495     


Thr Gly Lys Val Asn Lys Ile Thr Ile Thr Asn Asp Lys Gly Arg Leu 
            500                 505                 510         


Ser Lys Glu Glu Ile Glu Arg Met Val Leu Asp Ala Glu Lys Tyr Lys 
        515                 520                 525             


Ala Glu Asp Glu Val Gln Arg Glu Lys Ile Ala Ala Lys Asn Ala Leu 
    530                 535                 540                 


Glu Ser Tyr Ala Phe Asn Met Lys Ser Val Val Ser Asp Glu Gly Leu 
545                 550                 555                 560 


Lys Gly Lys Ile Ser Glu Ser Asp Lys Asn Lys Ile Leu Asp Lys Cys 
                565                 570                 575     


Asn Glu Leu Leu Ser Trp Leu Glu Val Asn Gln Leu Ala Glu Lys Asp 
            580                 585                 590         


Glu Phe Asp His Lys Arg Lys Glu Leu Glu Gln Met Cys Asn Pro Ile 
        595                 600                 605             


Ile Thr Lys Leu Tyr Gln Gly Gly Cys Thr Gly Pro Ala Cys Gly Thr 
    610                 615                 620                 


Gly Tyr Val Pro Gly Arg Pro Ala Thr Gly Pro Thr Ile Glu Glu Val 
625                 630                 635                 640 


Asp 
    


<210>  53
<211>  639
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  53

Met Ser Ala Arg Gly Pro Ala Ile Gly Ile Asp Leu Gly Thr Thr Tyr 
1               5                   10                  15      


Ser Cys Val Gly Val Phe Gln His Gly Lys Val Glu Ile Ile Ala Asn 
            20                  25                  30          


Asp Gln Gly Asn Arg Thr Thr Pro Ser Tyr Val Ala Phe Thr Asp Thr 
        35                  40                  45              


Glu Arg Leu Ile Gly Asp Ala Ala Lys Asn Gln Val Ala Met Asn Pro 
    50                  55                  60                  


Thr Asn Thr Ile Phe Asp Ala Lys Arg Leu Ile Gly Arg Lys Phe Glu 
65                  70                  75                  80  


Asp Ala Thr Val Gln Ser Asp Met Lys His Trp Pro Phe Arg Val Val 
                85                  90                  95      


Ser Glu Gly Gly Lys Pro Lys Val Gln Val Glu Tyr Lys Gly Glu Thr 
            100                 105                 110         


Lys Thr Phe Phe Pro Glu Glu Ile Ser Ser Met Val Leu Thr Lys Met 
        115                 120                 125             


Lys Glu Ile Ala Glu Ala Tyr Leu Gly Gly Lys Val His Ser Ala Val 
    130                 135                 140                 


Ile Thr Val Pro Ala Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr Lys 
145                 150                 155                 160 


Asp Ala Gly Thr Ile Thr Gly Leu Asn Val Leu Arg Ile Ile Asn Glu 
                165                 170                 175     


Pro Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Lys Lys Gly Cys Ala 
            180                 185                 190         


Gly Gly Glu Lys Asn Val Leu Ile Phe Asp Leu Gly Gly Gly Thr Phe 
        195                 200                 205             


Asp Val Ser Ile Leu Thr Ile Glu Asp Gly Ile Phe Glu Val Lys Ser 
    210                 215                 220                 


Thr Ala Gly Asp Thr His Leu Gly Gly Glu Asp Phe Asp Asn Arg Met 
225                 230                 235                 240 


Val Ser His Leu Ala Glu Glu Phe Lys Arg Lys His Lys Lys Asp Ile 
                245                 250                 255     


Gly Pro Asn Lys Arg Ala Val Arg Arg Leu Arg Thr Ala Cys Glu Arg 
            260                 265                 270         


Ala Lys Arg Thr Leu Ser Ser Ser Thr Gln Ala Ser Ile Glu Ile Asp 
        275                 280                 285             


Ser Leu Tyr Glu Gly Val Asp Phe Tyr Thr Ser Ile Thr Arg Ala Arg 
    290                 295                 300                 


Phe Glu Glu Leu Asn Ala Asp Leu Phe Arg Gly Thr Leu Glu Pro Val 
305                 310                 315                 320 


Glu Lys Ala Leu Arg Asp Ala Lys Leu Asp Lys Gly Gln Ile Gln Glu 
                325                 330                 335     


Ile Val Leu Val Gly Gly Ser Thr Arg Ile Pro Lys Ile Gln Lys Leu 
            340                 345                 350         


Leu Gln Asp Phe Phe Asn Gly Lys Glu Leu Asn Lys Ser Ile Asn Pro 
        355                 360                 365             


Asp Glu Ala Val Ala Tyr Gly Ala Ala Val Gln Ala Ala Ile Leu Ile 
    370                 375                 380                 


Gly Asp Lys Ser Glu Asn Val Gln Asp Leu Leu Leu Leu Asp Val Thr 
385                 390                 395                 400 


Pro Leu Ser Leu Gly Ile Glu Thr Ala Gly Gly Val Met Thr Pro Leu 
                405                 410                 415     


Ile Lys Arg Asn Thr Thr Ile Pro Thr Lys Gln Thr Gln Thr Phe Thr 
            420                 425                 430         


Thr Tyr Ser Asp Asn Gln Ser Ser Val Leu Val Gln Val Tyr Glu Gly 
        435                 440                 445             


Glu Arg Ala Met Thr Lys Asp Asn Asn Leu Leu Gly Lys Phe Asp Leu 
    450                 455                 460                 


Thr Gly Ile Pro Pro Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr 
465                 470                 475                 480 


Phe Asp Ile Asp Ala Asn Gly Ile Leu Asn Val Thr Ala Ala Asp Lys 
                485                 490                 495     


Ser Thr Gly Lys Glu Asn Lys Ile Thr Ile Thr Asn Asp Lys Gly Arg 
            500                 505                 510         


Leu Ser Lys Asp Asp Ile Asp Arg Met Val Gln Glu Ala Glu Arg Tyr 
        515                 520                 525             


Lys Ser Glu Asp Glu Ala Asn Arg Asp Arg Val Ala Ala Lys Asn Ala 
    530                 535                 540                 


Leu Glu Ser Tyr Thr Tyr Asn Ile Lys Gln Thr Val Glu Asp Glu Lys 
545                 550                 555                 560 


Leu Arg Gly Lys Ile Ser Glu Gln Asp Lys Asn Lys Ile Leu Asp Lys 
                565                 570                 575     


Cys Gln Glu Val Ile Asn Trp Leu Asp Arg Asn Gln Met Ala Glu Lys 
            580                 585                 590         


Asp Glu Tyr Glu His Lys Gln Lys Glu Leu Glu Arg Val Cys Asn Pro 
        595                 600                 605             


Ile Ile Ser Lys Leu Tyr Gln Gly Gly Pro Gly Gly Gly Ser Gly Gly 
    610                 615                 620                 


Gly Gly Ser Gly Ala Ser Gly Gly Pro Thr Ile Glu Glu Val Asp 
625                 630                 635                 


<210>  54
<211>  840
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  54

Met Ser Val Val Gly Ile Asp Leu Gly Phe Gln Ser Cys Tyr Val Ala 
1               5                   10                  15      


Val Ala Arg Ala Gly Gly Ile Glu Thr Ile Ala Asn Glu Tyr Ser Asp 
            20                  25                  30          


Arg Cys Thr Pro Ala Cys Ile Ser Phe Gly Pro Lys Asn Arg Ser Ile 
        35                  40                  45              


Gly Ala Ala Ala Lys Ser Gln Val Ile Ser Asn Ala Lys Asn Thr Val 
    50                  55                  60                  


Gln Gly Phe Lys Arg Phe His Gly Arg Ala Phe Ser Asp Pro Phe Val 
65                  70                  75                  80  


Glu Ala Glu Lys Ser Asn Leu Ala Tyr Asp Ile Val Gln Leu Pro Thr 
                85                  90                  95      


Gly Leu Thr Gly Ile Lys Val Thr Tyr Met Glu Glu Glu Arg Asn Phe 
            100                 105                 110         


Thr Thr Glu Gln Val Thr Ala Met Leu Leu Ser Lys Leu Lys Glu Thr 
        115                 120                 125             


Ala Glu Ser Val Leu Lys Lys Pro Val Val Asp Cys Val Val Ser Val 
    130                 135                 140                 


Pro Cys Phe Tyr Thr Asp Ala Glu Arg Arg Ser Val Met Asp Ala Thr 
145                 150                 155                 160 


Gln Ile Ala Gly Leu Asn Cys Leu Arg Leu Met Asn Glu Thr Thr Ala 
                165                 170                 175     


Val Ala Leu Ala Tyr Gly Ile Tyr Lys Gln Asp Leu Pro Ala Leu Glu 
            180                 185                 190         


Glu Lys Pro Arg Asn Val Val Phe Val Asp Met Gly His Ser Ala Tyr 
        195                 200                 205             


Gln Val Ser Val Cys Ala Phe Asn Arg Gly Lys Leu Lys Val Leu Ala 
    210                 215                 220                 


Thr Ala Phe Asp Thr Thr Leu Gly Gly Arg Lys Phe Asp Glu Val Leu 
225                 230                 235                 240 


Val Asn His Phe Cys Glu Glu Phe Gly Lys Lys Tyr Lys Leu Asp Ile 
                245                 250                 255     


Lys Ser Lys Ile Arg Ala Leu Leu Arg Leu Ser Gln Glu Cys Glu Lys 
            260                 265                 270         


Leu Lys Lys Leu Met Ser Ala Asn Ala Ser Asp Leu Pro Leu Ser Ile 
        275                 280                 285             


Glu Cys Phe Met Asn Asp Val Asp Val Ser Gly Thr Met Asn Arg Gly 
    290                 295                 300                 


Lys Phe Leu Glu Met Cys Asn Asp Leu Leu Ala Arg Val Glu Pro Pro 
305                 310                 315                 320 


Leu Arg Ser Val Leu Glu Gln Thr Lys Leu Lys Lys Glu Asp Ile Tyr 
                325                 330                 335     


Ala Val Glu Ile Val Gly Gly Ala Thr Arg Ile Pro Ala Val Lys Glu 
            340                 345                 350         


Lys Ile Ser Lys Phe Phe Gly Lys Glu Leu Ser Thr Thr Leu Asn Ala 
        355                 360                 365             


Asp Glu Ala Val Thr Arg Gly Cys Ala Leu Gln Cys Ala Ile Leu Ser 
    370                 375                 380                 


Pro Ala Phe Lys Val Arg Glu Phe Ser Ile Thr Asp Val Val Pro Tyr 
385                 390                 395                 400 


Pro Ile Ser Leu Arg Trp Asn Ser Pro Ala Glu Glu Gly Ser Ser Asp 
                405                 410                 415     


Cys Glu Val Phe Ser Lys Asn His Ala Ala Pro Phe Ser Lys Val Leu 
            420                 425                 430         


Thr Phe Tyr Arg Lys Glu Pro Phe Thr Leu Glu Ala Tyr Tyr Ser Ser 
        435                 440                 445             


Pro Gln Asp Leu Pro Tyr Pro Asp Pro Ala Ile Ala Gln Phe Ser Val 
    450                 455                 460                 


Gln Lys Val Thr Pro Gln Ser Asp Gly Ser Ser Ser Lys Val Lys Val 
465                 470                 475                 480 


Lys Val Arg Val Asn Val His Gly Ile Phe Ser Val Ser Ser Ala Ser 
                485                 490                 495     


Leu Val Glu Val His Lys Ser Glu Glu Asn Glu Glu Pro Met Glu Thr 
            500                 505                 510         


Asp Gln Asn Ala Lys Glu Glu Glu Lys Met Gln Val Asp Gln Glu Glu 
        515                 520                 525             


Pro His Val Glu Glu Gln Gln Gln Gln Thr Pro Ala Glu Asn Lys Ala 
    530                 535                 540                 


Glu Ser Glu Glu Met Glu Thr Ser Gln Ala Gly Ser Lys Asp Lys Lys 
545                 550                 555                 560 


Met Asp Gln Pro Pro Gln Ala Lys Lys Ala Lys Val Lys Thr Ser Thr 
                565                 570                 575     


Val Asp Leu Pro Ile Glu Asn Gln Leu Leu Trp Gln Ile Asp Arg Glu 
            580                 585                 590         


Met Leu Asn Leu Tyr Ile Glu Asn Glu Gly Lys Met Ile Met Gln Asp 
        595                 600                 605             


Lys Leu Glu Lys Glu Arg Asn Asp Ala Lys Asn Ala Val Glu Glu Tyr 
    610                 615                 620                 


Val Tyr Glu Met Arg Asp Lys Leu Ser Gly Glu Tyr Glu Lys Phe Val 
625                 630                 635                 640 


Ser Glu Asp Asp Arg Asn Ser Phe Thr Leu Lys Leu Glu Asp Thr Glu 
                645                 650                 655     


Asn Trp Leu Tyr Glu Asp Gly Glu Asp Gln Pro Lys Gln Val Tyr Val 
            660                 665                 670         


Asp Lys Leu Ala Glu Leu Lys Asn Leu Gly Gln Pro Ile Lys Ile Arg 
        675                 680                 685             


Phe Gln Glu Ser Glu Glu Arg Pro Lys Leu Phe Glu Glu Leu Gly Lys 
    690                 695                 700                 


Gln Ile Gln Gln Tyr Met Lys Ile Ile Ser Ser Phe Lys Asn Lys Glu 
705                 710                 715                 720 


Asp Gln Tyr Asp His Leu Asp Ala Ala Asp Met Thr Lys Val Glu Lys 
                725                 730                 735     


Ser Thr Asn Glu Ala Met Glu Trp Met Asn Asn Lys Leu Asn Leu Gln 
            740                 745                 750         


Asn Lys Gln Ser Leu Thr Met Asp Pro Val Val Lys Ser Lys Glu Ile 
        755                 760                 765             


Glu Ala Lys Ile Lys Glu Leu Thr Ser Thr Cys Ser Pro Ile Ile Ser 
    770                 775                 780                 


Lys Pro Lys Pro Lys Val Glu Pro Pro Lys Glu Glu Gln Lys Asn Ala 
785                 790                 795                 800 


Glu Gln Asn Gly Pro Val Asp Gly Gln Gly Asp Asn Pro Gly Pro Gln 
                805                 810                 815     


Ala Ala Glu Gln Gly Thr Asp Thr Ala Val Pro Ser Asp Ser Asp Lys 
            820                 825                 830         


Lys Leu Pro Glu Met Asp Ile Asp 
        835                 840 


<210>  55
<211>  839
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  55

Met Ser Val Val Gly Ile Asp Leu Gly Phe Leu Asn Cys Tyr Ile Ala 
1               5                   10                  15      


Val Ala Arg Ser Gly Gly Ile Glu Thr Ile Ala Asn Glu Tyr Ser Asp 
            20                  25                  30          


Arg Cys Thr Pro Ala Cys Ile Ser Leu Gly Ser Arg Thr Arg Ala Ile 
        35                  40                  45              


Gly Asn Ala Ala Lys Ser Gln Ile Val Thr Asn Val Arg Asn Thr Ile 
    50                  55                  60                  


His Gly Phe Lys Lys Leu His Gly Arg Ser Phe Asp Asp Pro Ile Val 
65                  70                  75                  80  


Gln Thr Glu Arg Ile Arg Leu Pro Tyr Glu Leu Gln Lys Met Pro Asn 
                85                  90                  95      


Gly Ser Ala Gly Val Lys Val Arg Tyr Leu Glu Glu Glu Arg Pro Phe 
            100                 105                 110         


Ala Ile Glu Gln Val Thr Gly Met Leu Leu Ala Lys Leu Lys Glu Thr 
        115                 120                 125             


Ser Glu Asn Ala Leu Lys Lys Pro Val Ala Asp Cys Val Ile Ser Ile 
    130                 135                 140                 


Pro Ser Phe Phe Thr Asp Ala Glu Arg Arg Ser Val Met Ala Ala Ala 
145                 150                 155                 160 


Gln Val Ala Gly Leu Asn Cys Leu Arg Leu Met Asn Glu Thr Thr Ala 
                165                 170                 175     


Val Ala Leu Ala Tyr Gly Ile Tyr Lys Gln Asp Leu Pro Pro Leu Asp 
            180                 185                 190         


Glu Lys Pro Arg Asn Val Val Phe Ile Asp Met Gly His Ser Ala Tyr 
        195                 200                 205             


Gln Val Leu Val Cys Ala Phe Asn Lys Gly Lys Leu Lys Val Leu Ala 
    210                 215                 220                 


Thr Thr Phe Asp Pro Tyr Leu Gly Gly Arg Asn Phe Asp Glu Ala Leu 
225                 230                 235                 240 


Val Asp Tyr Phe Cys Asp Glu Phe Lys Thr Lys Tyr Lys Ile Asn Val 
                245                 250                 255     


Lys Glu Asn Ser Arg Ala Leu Leu Arg Leu Tyr Gln Glu Cys Glu Lys 
            260                 265                 270         


Leu Lys Lys Leu Met Ser Ala Asn Ala Ser Asp Leu Pro Leu Asn Ile 
        275                 280                 285             


Glu Cys Phe Met Asn Asp Leu Asp Val Ser Ser Lys Met Asn Arg Ala 
    290                 295                 300                 


Gln Phe Glu Gln Leu Cys Ala Ser Leu Leu Ala Arg Val Glu Pro Pro 
305                 310                 315                 320 


Leu Lys Ala Val Met Glu Gln Ala Asn Leu Gln Arg Glu Asp Ile Ser 
                325                 330                 335     


Ser Ile Glu Ile Val Gly Gly Ala Thr Arg Ile Pro Ala Val Lys Glu 
            340                 345                 350         


Gln Ile Thr Lys Phe Phe Leu Lys Asp Ile Ser Thr Thr Leu Asn Ala 
        355                 360                 365             


Asp Glu Ala Val Ala Arg Gly Cys Ala Leu Gln Cys Ala Ile Leu Ser 
    370                 375                 380                 


Pro Ala Phe Lys Val Arg Glu Phe Ser Ile Thr Asp Leu Val Pro Tyr 
385                 390                 395                 400 


Ser Ile Thr Leu Arg Trp Lys Thr Ser Phe Glu Asp Gly Ser Gly Glu 
                405                 410                 415     


Cys Glu Val Phe Cys Lys Asn His Pro Ala Pro Phe Ser Lys Val Ile 
            420                 425                 430         


Thr Phe His Lys Lys Glu Pro Phe Glu Leu Glu Ala Phe Tyr Thr Asn 
        435                 440                 445             


Leu His Glu Val Pro Tyr Pro Asp Ala Arg Ile Gly Ser Phe Thr Ile 
    450                 455                 460                 


Gln Asn Val Phe Pro Gln Ser Asp Gly Asp Ser Ser Lys Val Lys Val 
465                 470                 475                 480 


Lys Val Arg Val Asn Ile His Gly Ile Phe Ser Val Ala Ser Ala Ser 
                485                 490                 495     


Val Ile Glu Lys Gln Asn Leu Glu Gly Asp His Ser Asp Ala Pro Met 
            500                 505                 510         


Glu Thr Glu Thr Ser Phe Lys Asn Glu Asn Lys Asp Asn Met Asp Lys 
        515                 520                 525             


Met Gln Val Asp Gln Glu Glu Gly His Gln Lys Cys His Ala Glu His 
    530                 535                 540                 


Thr Pro Glu Glu Glu Ile Asp His Thr Gly Ala Lys Thr Lys Ser Ala 
545                 550                 555                 560 


Val Ser Asp Lys Gln Asp Arg Leu Asn Gln Thr Leu Lys Lys Gly Lys 
                565                 570                 575     


Val Lys Ser Ile Asp Leu Pro Ile Gln Ser Ser Leu Cys Arg Gln Leu 
            580                 585                 590         


Gly Gln Asp Leu Leu Asn Ser Tyr Ile Glu Asn Glu Gly Lys Met Ile 
        595                 600                 605             


Met Gln Asp Lys Leu Glu Lys Glu Arg Asn Asp Ala Lys Asn Ala Val 
    610                 615                 620                 


Glu Glu Tyr Val Tyr Asp Phe Arg Asp Arg Leu Gly Thr Val Tyr Glu 
625                 630                 635                 640 


Lys Phe Ile Thr Pro Glu Asp Leu Ser Lys Leu Ser Ala Val Leu Glu 
                645                 650                 655     


Asp Thr Glu Asn Trp Leu Tyr Glu Asp Gly Glu Asp Gln Pro Lys Gln 
            660                 665                 670         


Val Tyr Val Asp Lys Leu Gln Glu Leu Lys Lys Tyr Gly Gln Pro Ile 
        675                 680                 685             


Gln Met Lys Tyr Met Glu His Glu Glu Arg Pro Lys Ala Leu Asn Asp 
    690                 695                 700                 


Leu Gly Lys Lys Ile Gln Leu Val Met Lys Val Ile Glu Ala Tyr Arg 
705                 710                 715                 720 


Asn Lys Asp Glu Arg Tyr Asp His Leu Asp Pro Thr Glu Met Glu Lys 
                725                 730                 735     


Val Glu Lys Cys Ile Ser Asp Ala Met Ser Trp Leu Asn Ser Lys Met 
            740                 745                 750         


Asn Ala Gln Asn Lys Leu Ser Leu Thr Gln Asp Pro Val Val Lys Val 
        755                 760                 765             


Ser Glu Ile Val Ala Lys Ser Lys Glu Leu Asp Asn Phe Cys Asn Pro 
    770                 775                 780                 


Ile Ile Tyr Lys Pro Lys Pro Lys Ala Glu Val Pro Glu Asp Lys Pro 
785                 790                 795                 800 


Lys Ala Asn Ser Glu His Asn Gly Pro Met Asp Gly Gln Ser Gly Thr 
                805                 810                 815     


Glu Thr Lys Ser Asp Ser Thr Lys Asp Ser Ser Gln His Thr Lys Ser 
            820                 825                 830         


Ser Gly Glu Met Glu Val Asp 
        835                 


<210>  56
<211>  654
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  56

Met Lys Leu Ser Leu Val Ala Ala Met Leu Leu Leu Leu Ser Ala Ala 
1               5                   10                  15      


Arg Ala Glu Glu Glu Asp Lys Lys Glu Asp Val Gly Thr Val Val Gly 
            20                  25                  30          


Ile Asp Leu Gly Thr Thr Tyr Ser Cys Val Gly Val Phe Lys Asn Gly 
        35                  40                  45              


Arg Val Glu Ile Ile Ala Asn Asp Gln Gly Asn Arg Ile Thr Pro Ser 
    50                  55                  60                  


Tyr Val Ala Phe Thr Pro Glu Gly Glu Arg Leu Ile Gly Asp Ala Ala 
65                  70                  75                  80  


Lys Asn Gln Leu Thr Ser Asn Pro Glu Asn Thr Val Phe Asp Ala Lys 
                85                  90                  95      


Arg Leu Ile Gly Arg Thr Trp Asn Asp Pro Ser Val Gln Gln Asp Ile 
            100                 105                 110         


Lys Phe Leu Pro Phe Lys Val Val Glu Lys Lys Thr Lys Pro Tyr Ile 
        115                 120                 125             


Gln Val Asp Ile Gly Gly Gly Gln Thr Lys Thr Phe Ala Pro Glu Glu 
    130                 135                 140                 


Ile Ser Ala Met Val Leu Thr Lys Met Lys Glu Thr Ala Glu Ala Tyr 
145                 150                 155                 160 


Leu Gly Lys Lys Val Thr His Ala Val Val Thr Val Pro Ala Tyr Phe 
                165                 170                 175     


Asn Asp Ala Gln Arg Gln Ala Thr Lys Asp Ala Gly Thr Ile Ala Gly 
            180                 185                 190         


Leu Asn Val Met Arg Ile Ile Asn Glu Pro Thr Ala Ala Ala Ile Ala 
        195                 200                 205             


Tyr Gly Leu Asp Lys Arg Glu Gly Glu Lys Asn Ile Leu Val Phe Asp 
    210                 215                 220                 


Leu Gly Gly Gly Thr Phe Asp Val Ser Leu Leu Thr Ile Asp Asn Gly 
225                 230                 235                 240 


Val Phe Glu Val Val Ala Thr Asn Gly Asp Thr His Leu Gly Gly Glu 
                245                 250                 255     


Asp Phe Asp Gln Arg Val Met Glu His Phe Ile Lys Leu Tyr Lys Lys 
            260                 265                 270         


Lys Thr Gly Lys Asp Val Arg Lys Asp Asn Arg Ala Val Gln Lys Leu 
        275                 280                 285             


Arg Arg Glu Val Glu Lys Ala Lys Arg Ala Leu Ser Ser Gln His Gln 
    290                 295                 300                 


Ala Arg Ile Glu Ile Glu Ser Phe Tyr Glu Gly Glu Asp Phe Ser Glu 
305                 310                 315                 320 


Thr Leu Thr Arg Ala Lys Phe Glu Glu Leu Asn Met Asp Leu Phe Arg 
                325                 330                 335     


Ser Thr Met Lys Pro Val Gln Lys Val Leu Glu Asp Ser Asp Leu Lys 
            340                 345                 350         


Lys Ser Asp Ile Asp Glu Ile Val Leu Val Gly Gly Ser Thr Arg Ile 
        355                 360                 365             


Pro Lys Ile Gln Gln Leu Val Lys Glu Phe Phe Asn Gly Lys Glu Pro 
    370                 375                 380                 


Ser Arg Gly Ile Asn Pro Asp Glu Ala Val Ala Tyr Gly Ala Ala Val 
385                 390                 395                 400 


Gln Ala Gly Val Leu Ser Gly Asp Gln Asp Thr Gly Asp Leu Val Leu 
                405                 410                 415     


Leu Asp Val Cys Pro Leu Thr Leu Gly Ile Glu Thr Val Gly Gly Val 
            420                 425                 430         


Met Thr Lys Leu Ile Pro Arg Asn Thr Val Val Pro Thr Lys Lys Ser 
        435                 440                 445             


Gln Ile Phe Ser Thr Ala Ser Asp Asn Gln Pro Thr Val Thr Ile Lys 
    450                 455                 460                 


Val Tyr Glu Gly Glu Arg Pro Leu Thr Lys Asp Asn His Leu Leu Gly 
465                 470                 475                 480 


Thr Phe Asp Leu Thr Gly Ile Pro Pro Ala Pro Arg Gly Val Pro Gln 
                485                 490                 495     


Ile Glu Val Thr Phe Glu Ile Asp Val Asn Gly Ile Leu Arg Val Thr 
            500                 505                 510         


Ala Glu Asp Lys Gly Thr Gly Asn Lys Asn Lys Ile Thr Ile Thr Asn 
        515                 520                 525             


Asp Gln Asn Arg Leu Thr Pro Glu Glu Ile Glu Arg Met Val Asn Asp 
    530                 535                 540                 


Ala Glu Lys Phe Ala Glu Glu Asp Lys Lys Leu Lys Glu Arg Ile Asp 
545                 550                 555                 560 


Thr Arg Asn Glu Leu Glu Ser Tyr Ala Tyr Ser Leu Lys Asn Gln Ile 
                565                 570                 575     


Gly Asp Lys Glu Lys Leu Gly Gly Lys Leu Ser Ser Glu Asp Lys Glu 
            580                 585                 590         


Thr Met Glu Lys Ala Val Glu Glu Lys Ile Glu Trp Leu Glu Ser His 
        595                 600                 605             


Gln Asp Ala Asp Ile Glu Asp Phe Lys Ala Lys Lys Lys Glu Leu Glu 
    610                 615                 620                 


Glu Ile Val Gln Pro Ile Ile Ser Lys Leu Tyr Gly Ser Ala Gly Pro 
625                 630                 635                 640 


Pro Pro Thr Gly Glu Glu Asp Thr Ala Glu Lys Asp Glu Leu 
                645                 650                 


<210>  57
<211>  643
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  57

Met Gln Ala Pro Arg Glu Leu Ala Val Gly Ile Asp Leu Gly Thr Thr 
1               5                   10                  15      


Tyr Ser Cys Val Gly Val Phe Gln Gln Gly Arg Val Glu Ile Leu Ala 
            20                  25                  30          


Asn Asp Gln Gly Asn Arg Thr Thr Pro Ser Tyr Val Ala Phe Thr Asp 
        35                  40                  45              


Thr Glu Arg Leu Val Gly Asp Ala Ala Lys Ser Gln Ala Ala Leu Asn 
    50                  55                  60                  


Pro His Asn Thr Val Phe Asp Ala Lys Arg Leu Ile Gly Arg Lys Phe 
65                  70                  75                  80  


Ala Asp Thr Thr Val Gln Ser Asp Met Lys His Trp Pro Phe Arg Val 
                85                  90                  95      


Val Ser Glu Gly Gly Lys Pro Lys Val Arg Val Cys Tyr Arg Gly Glu 
            100                 105                 110         


Asp Lys Thr Phe Tyr Pro Glu Glu Ile Ser Ser Met Val Leu Ser Lys 
        115                 120                 125             


Met Lys Glu Thr Ala Glu Ala Tyr Leu Gly Gln Pro Val Lys His Ala 
    130                 135                 140                 


Val Ile Thr Val Pro Ala Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr 
145                 150                 155                 160 


Lys Asp Ala Gly Ala Ile Ala Gly Leu Asn Val Leu Arg Ile Ile Asn 
                165                 170                 175     


Glu Pro Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Arg Arg Gly Ala 
            180                 185                 190         


Gly Glu Arg Asn Val Leu Ile Phe Asp Leu Gly Gly Gly Thr Phe Asp 
        195                 200                 205             


Val Ser Val Leu Ser Ile Asp Ala Gly Val Phe Glu Val Lys Ala Thr 
    210                 215                 220                 


Ala Gly Asp Thr His Leu Gly Gly Glu Asp Phe Asp Asn Arg Leu Val 
225                 230                 235                 240 


Asn His Phe Met Glu Glu Phe Arg Arg Lys His Gly Lys Asp Leu Ser 
                245                 250                 255     


Gly Asn Lys Arg Ala Leu Arg Arg Leu Arg Thr Ala Cys Glu Arg Ala 
            260                 265                 270         


Lys Arg Thr Leu Ser Ser Ser Thr Gln Ala Thr Leu Glu Ile Asp Ser 
        275                 280                 285             


Leu Phe Glu Gly Val Asp Phe Tyr Thr Ser Ile Thr Arg Ala Arg Phe 
    290                 295                 300                 


Glu Glu Leu Cys Ser Asp Leu Phe Arg Ser Thr Leu Glu Pro Val Glu 
305                 310                 315                 320 


Lys Ala Leu Arg Asp Ala Lys Leu Asp Lys Ala Gln Ile His Asp Val 
                325                 330                 335     


Val Leu Val Gly Gly Ser Thr Arg Ile Pro Lys Val Gln Lys Leu Leu 
            340                 345                 350         


Gln Asp Phe Phe Asn Gly Lys Glu Leu Asn Lys Ser Ile Asn Pro Asp 
        355                 360                 365             


Glu Ala Val Ala Tyr Gly Ala Ala Val Gln Ala Ala Val Leu Met Gly 
    370                 375                 380                 


Asp Lys Cys Glu Lys Val Gln Asp Leu Leu Leu Leu Asp Val Ala Pro 
385                 390                 395                 400 


Leu Ser Leu Gly Leu Glu Thr Ala Gly Gly Val Met Thr Thr Leu Ile 
                405                 410                 415     


Gln Arg Asn Ala Thr Ile Pro Thr Lys Gln Thr Gln Thr Phe Thr Thr 
            420                 425                 430         


Tyr Ser Asp Asn Gln Pro Gly Val Phe Ile Gln Val Tyr Glu Gly Glu 
        435                 440                 445             


Arg Ala Met Thr Lys Asp Asn Asn Leu Leu Gly Arg Phe Glu Leu Ser 
    450                 455                 460                 


Gly Ile Pro Pro Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr Phe 
465                 470                 475                 480 


Asp Ile Asp Ala Asn Gly Ile Leu Ser Val Thr Ala Thr Asp Arg Ser 
                485                 490                 495     


Thr Gly Lys Ala Asn Lys Ile Thr Ile Thr Asn Asp Lys Gly Arg Leu 
            500                 505                 510         


Ser Lys Glu Glu Val Glu Arg Met Val His Glu Ala Glu Gln Tyr Lys 
        515                 520                 525             


Ala Glu Asp Glu Ala Gln Arg Asp Arg Val Ala Ala Lys Asn Ser Leu 
    530                 535                 540                 


Glu Ala His Val Phe His Val Lys Gly Ser Leu Gln Glu Glu Ser Leu 
545                 550                 555                 560 


Arg Asp Lys Ile Pro Glu Glu Asp Arg Arg Lys Met Gln Asp Lys Cys 
                565                 570                 575     


Arg Glu Val Leu Ala Trp Leu Glu His Asn Gln Leu Ala Glu Lys Glu 
            580                 585                 590         


Glu Tyr Glu His Gln Lys Arg Glu Leu Glu Gln Ile Cys Arg Pro Ile 
        595                 600                 605             


Phe Ser Arg Leu Tyr Gly Gly Pro Gly Val Pro Gly Gly Ser Ser Cys 
    610                 615                 620                 


Gly Thr Gln Ala Arg Gln Gly Asp Pro Ser Thr Gly Pro Ile Ile Glu 
625                 630                 635                 640 


Glu Val Asp 
            


<210>  58
<211>  367
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__P48741__HsHSPA7

<400>  58

Met Gln Ala Pro Arg Glu Leu Ala Val Gly Ile Asp Leu Gly Thr Thr 
1               5                   10                  15      


Tyr Ser Cys Val Gly Val Phe Gln Gln Gly Arg Val Glu Ile Leu Ala 
            20                  25                  30          


Asn Asp Gln Gly Asn Arg Thr Thr Pro Ser Tyr Val Ala Phe Thr Asp 
        35                  40                  45              


Thr Glu Arg Leu Val Gly Asp Ala Ala Lys Ser Gln Ala Ala Leu Asn 
    50                  55                  60                  


Pro His Asn Thr Val Phe Asp Ala Lys Arg Leu Ile Gly Arg Lys Phe 
65                  70                  75                  80  


Ala Asp Thr Thr Val Gln Ser Asp Met Lys His Trp Pro Phe Gln Val 
                85                  90                  95      


Val Ser Glu Gly Gly Lys Pro Lys Val Arg Val Cys Tyr Arg Gly Glu 
            100                 105                 110         


Asp Lys Thr Phe Tyr Pro Glu Glu Ile Ser Ser Met Val Leu Ser Lys 
        115                 120                 125             


Met Lys Glu Thr Ala Glu Ala Tyr Leu Gly Gln Pro Val Lys His Ala 
    130                 135                 140                 


Val Ile Thr Val Pro Thr Tyr Phe Ser Asn Ser Gln Arg Gln Ala Thr 
145                 150                 155                 160 


Lys Asp Ala Gly Ala Ile Ala Gly Leu Lys Val Leu Pro Ile Ile Asn 
                165                 170                 175     


Glu Ala Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Arg Arg Gly Ala 
            180                 185                 190         


Gly Lys Arg Asn Val Leu Ile Phe Asp Leu Gly Gly Gly Thr Phe Asp 
        195                 200                 205             


Val Ser Val Leu Ser Ile Asp Ala Gly Val Phe Glu Val Lys Ala Thr 
    210                 215                 220                 


Ala Gly Asp Thr His Leu Gly Gly Glu Asp Phe Asp Asn Arg Leu Val 
225                 230                 235                 240 


Asn His Phe Met Glu Glu Phe Arg Arg Lys His Gly Lys Asp Leu Ser 
                245                 250                 255     


Gly Asn Lys Arg Ala Leu Arg Arg Leu Arg Thr Ala Cys Glu Arg Ala 
            260                 265                 270         


Lys Arg Thr Pro Ser Ser Ser Thr Gln Ala Thr Leu Glu Ile Asp Ser 
        275                 280                 285             


Leu Phe Glu Gly Val Asp Phe Tyr Lys Ser Ile Thr Arg Ala Arg Phe 
    290                 295                 300                 


Glu Glu Leu Cys Ser Asp Leu Phe Arg Ser Thr Leu Glu Pro Val Glu 
305                 310                 315                 320 


Lys Ala Leu Arg Asp Ala Lys Leu Asp Lys Ala Gln Ile His Asp Phe 
                325                 330                 335     


Val Leu Gly Gly Gly Leu His Ser His Pro Gln Gly Ala Glu Val Ala 
            340                 345                 350         


Ala Gly Leu Leu Gln Arg Gln Gly Ala Glu Gln Glu His Gln Pro 
        355                 360                 365         


<210>  59
<211>  646
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  59

Met Ser Lys Gly Pro Ala Val Gly Ile Asp Leu Gly Thr Thr Tyr Ser 
1               5                   10                  15      


Cys Val Gly Val Phe Gln His Gly Lys Val Glu Ile Ile Ala Asn Asp 
            20                  25                  30          


Gln Gly Asn Arg Thr Thr Pro Ser Tyr Val Ala Phe Thr Asp Thr Glu 
        35                  40                  45              


Arg Leu Ile Gly Asp Ala Ala Lys Asn Gln Val Ala Met Asn Pro Thr 
    50                  55                  60                  


Asn Thr Val Phe Asp Ala Lys Arg Leu Ile Gly Arg Arg Phe Asp Asp 
65                  70                  75                  80  


Ala Val Val Gln Ser Asp Met Lys His Trp Pro Phe Met Val Val Asn 
                85                  90                  95      


Asp Ala Gly Arg Pro Lys Val Gln Val Glu Tyr Lys Gly Glu Thr Lys 
            100                 105                 110         


Ser Phe Tyr Pro Glu Glu Val Ser Ser Met Val Leu Thr Lys Met Lys 
        115                 120                 125             


Glu Ile Ala Glu Ala Tyr Leu Gly Lys Thr Val Thr Asn Ala Val Val 
    130                 135                 140                 


Thr Val Pro Ala Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr Lys Asp 
145                 150                 155                 160 


Ala Gly Thr Ile Ala Gly Leu Asn Val Leu Arg Ile Ile Asn Glu Pro 
                165                 170                 175     


Thr Ala Ala Ala Ile Ala Tyr Gly Leu Asp Lys Lys Val Gly Ala Glu 
            180                 185                 190         


Arg Asn Val Leu Ile Phe Asp Leu Gly Gly Gly Thr Phe Asp Val Ser 
        195                 200                 205             


Ile Leu Thr Ile Glu Asp Gly Ile Phe Glu Val Lys Ser Thr Ala Gly 
    210                 215                 220                 


Asp Thr His Leu Gly Gly Glu Asp Phe Asp Asn Arg Met Val Asn His 
225                 230                 235                 240 


Phe Ile Ala Glu Phe Lys Arg Lys His Lys Lys Asp Ile Ser Glu Asn 
                245                 250                 255     


Lys Arg Ala Val Arg Arg Leu Arg Thr Ala Cys Glu Arg Ala Lys Arg 
            260                 265                 270         


Thr Leu Ser Ser Ser Thr Gln Ala Ser Ile Glu Ile Asp Ser Leu Tyr 
        275                 280                 285             


Glu Gly Ile Asp Phe Tyr Thr Ser Ile Thr Arg Ala Arg Phe Glu Glu 
    290                 295                 300                 


Leu Asn Ala Asp Leu Phe Arg Gly Thr Leu Asp Pro Val Glu Lys Ala 
305                 310                 315                 320 


Leu Arg Asp Ala Lys Leu Asp Lys Ser Gln Ile His Asp Ile Val Leu 
                325                 330                 335     


Val Gly Gly Ser Thr Arg Ile Pro Lys Ile Gln Lys Leu Leu Gln Asp 
            340                 345                 350         


Phe Phe Asn Gly Lys Glu Leu Asn Lys Ser Ile Asn Pro Asp Glu Ala 
        355                 360                 365             


Val Ala Tyr Gly Ala Ala Val Gln Ala Ala Ile Leu Ser Gly Asp Lys 
    370                 375                 380                 


Ser Glu Asn Val Gln Asp Leu Leu Leu Leu Asp Val Thr Pro Leu Ser 
385                 390                 395                 400 


Leu Gly Ile Glu Thr Ala Gly Gly Val Met Thr Val Leu Ile Lys Arg 
                405                 410                 415     


Asn Thr Thr Ile Pro Thr Lys Gln Thr Gln Thr Phe Thr Thr Tyr Ser 
            420                 425                 430         


Asp Asn Gln Pro Gly Val Leu Ile Gln Val Tyr Glu Gly Glu Arg Ala 
        435                 440                 445             


Met Thr Lys Asp Asn Asn Leu Leu Gly Lys Phe Glu Leu Thr Gly Ile 
    450                 455                 460                 


Pro Pro Ala Pro Arg Gly Val Pro Gln Ile Glu Val Thr Phe Asp Ile 
465                 470                 475                 480 


Asp Ala Asn Gly Ile Leu Asn Val Ser Ala Val Asp Lys Ser Thr Gly 
                485                 490                 495     


Lys Glu Asn Lys Ile Thr Ile Thr Asn Asp Lys Gly Arg Leu Ser Lys 
            500                 505                 510         


Glu Asp Ile Glu Arg Met Val Gln Glu Ala Glu Lys Tyr Lys Ala Glu 
        515                 520                 525             


Asp Glu Lys Gln Arg Asp Lys Val Ser Ser Lys Asn Ser Leu Glu Ser 
    530                 535                 540                 


Tyr Ala Phe Asn Met Lys Ala Thr Val Glu Asp Glu Lys Leu Gln Gly 
545                 550                 555                 560 


Lys Ile Asn Asp Glu Asp Lys Gln Lys Ile Leu Asp Lys Cys Asn Glu 
                565                 570                 575     


Ile Ile Asn Trp Leu Asp Lys Asn Gln Thr Ala Glu Lys Glu Glu Phe 
            580                 585                 590         


Glu His Gln Gln Lys Glu Leu Glu Lys Val Cys Asn Pro Ile Ile Thr 
        595                 600                 605             


Lys Leu Tyr Gln Ser Ala Gly Gly Met Pro Gly Gly Met Pro Gly Gly 
    610                 615                 620                 


Phe Pro Gly Gly Gly Ala Pro Pro Ser Gly Gly Ala Ser Ser Gly Pro 
625                 630                 635                 640 


Thr Ile Glu Glu Val Asp 
                645     


<210>  60
<211>  679
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  60

Met Ile Ser Ala Ser Arg Ala Ala Ala Ala Arg Leu Val Gly Ala Ala 
1               5                   10                  15      


Ala Ser Arg Gly Pro Thr Ala Ala Arg His Gln Asp Ser Trp Asn Gly 
            20                  25                  30          


Leu Ser His Glu Ala Phe Arg Leu Val Ser Arg Arg Asp Tyr Ala Ser 
        35                  40                  45              


Glu Ala Ile Lys Gly Ala Val Val Gly Ile Asp Leu Gly Thr Thr Asn 
    50                  55                  60                  


Ser Cys Val Ala Val Met Glu Gly Lys Gln Ala Lys Val Leu Glu Asn 
65                  70                  75                  80  


Ala Glu Gly Ala Arg Thr Thr Pro Ser Val Val Ala Phe Thr Ala Asp 
                85                  90                  95      


Gly Glu Arg Leu Val Gly Met Pro Ala Lys Arg Gln Ala Val Thr Asn 
            100                 105                 110         


Pro Asn Asn Thr Phe Tyr Ala Thr Lys Arg Leu Ile Gly Arg Arg Tyr 
        115                 120                 125             


Asp Asp Pro Glu Val Gln Lys Asp Ile Lys Asn Val Pro Phe Lys Ile 
    130                 135                 140                 


Val Arg Ala Ser Asn Gly Asp Ala Trp Val Glu Ala His Gly Lys Leu 
145                 150                 155                 160 


Tyr Ser Pro Ser Gln Ile Gly Ala Phe Val Leu Met Lys Met Lys Glu 
                165                 170                 175     


Thr Ala Glu Asn Tyr Leu Gly His Thr Ala Lys Asn Ala Val Ile Thr 
            180                 185                 190         


Val Pro Ala Tyr Phe Asn Asp Ser Gln Arg Gln Ala Thr Lys Asp Ala 
        195                 200                 205             


Gly Gln Ile Ser Gly Leu Asn Val Leu Arg Val Ile Asn Glu Pro Thr 
    210                 215                 220                 


Ala Ala Ala Leu Ala Tyr Gly Leu Asp Lys Ser Glu Asp Lys Val Ile 
225                 230                 235                 240 


Ala Val Tyr Asp Leu Gly Gly Gly Thr Phe Asp Ile Ser Ile Leu Glu 
                245                 250                 255     


Ile Gln Lys Gly Val Phe Glu Val Lys Ser Thr Asn Gly Asp Thr Phe 
            260                 265                 270         


Leu Gly Gly Glu Asp Phe Asp Gln Ala Leu Leu Arg His Ile Val Lys 
        275                 280                 285             


Glu Phe Lys Arg Glu Thr Gly Val Asp Leu Thr Lys Asp Asn Met Ala 
    290                 295                 300                 


Leu Gln Arg Val Arg Glu Ala Ala Glu Lys Ala Lys Cys Glu Leu Ser 
305                 310                 315                 320 


Ser Ser Val Gln Thr Asp Ile Asn Leu Pro Tyr Leu Thr Met Asp Ser 
                325                 330                 335     


Ser Gly Pro Lys His Leu Asn Met Lys Leu Thr Arg Ala Gln Phe Glu 
            340                 345                 350         


Gly Ile Val Thr Asp Leu Ile Arg Arg Thr Ile Ala Pro Cys Gln Lys 
        355                 360                 365             


Ala Met Gln Asp Ala Glu Val Ser Lys Ser Asp Ile Gly Glu Val Ile 
    370                 375                 380                 


Leu Val Gly Gly Met Thr Arg Met Pro Lys Val Gln Gln Thr Val Gln 
385                 390                 395                 400 


Asp Leu Phe Gly Arg Ala Pro Ser Lys Ala Val Asn Pro Asp Glu Ala 
                405                 410                 415     


Val Ala Ile Gly Ala Ala Ile Gln Gly Gly Val Leu Ala Gly Asp Val 
            420                 425                 430         


Thr Asp Val Leu Leu Leu Asp Val Thr Pro Leu Ser Leu Gly Ile Glu 
        435                 440                 445             


Thr Leu Gly Gly Val Phe Thr Lys Leu Ile Asn Arg Asn Thr Thr Ile 
    450                 455                 460                 


Pro Thr Lys Lys Ser Gln Val Phe Ser Thr Ala Ala Asp Gly Gln Thr 
465                 470                 475                 480 


Gln Val Glu Ile Lys Val Cys Gln Gly Glu Arg Glu Met Ala Gly Asp 
                485                 490                 495     


Asn Lys Leu Leu Gly Gln Phe Thr Leu Ile Gly Ile Pro Pro Ala Pro 
            500                 505                 510         


Arg Gly Val Pro Gln Ile Glu Val Thr Phe Asp Ile Asp Ala Asn Gly 
        515                 520                 525             


Ile Val His Val Ser Ala Lys Asp Lys Gly Thr Gly Arg Glu Gln Gln 
    530                 535                 540                 


Ile Val Ile Gln Ser Ser Gly Gly Leu Ser Lys Asp Asp Ile Glu Asn 
545                 550                 555                 560 


Met Val Lys Asn Ala Glu Lys Tyr Ala Glu Glu Asp Arg Arg Lys Lys 
                565                 570                 575     


Glu Arg Val Glu Ala Val Asn Met Ala Glu Gly Ile Ile His Asp Thr 
            580                 585                 590         


Glu Thr Lys Met Glu Glu Phe Lys Asp Gln Leu Pro Ala Asp Glu Cys 
        595                 600                 605             


Asn Lys Leu Lys Glu Glu Ile Ser Lys Met Arg Glu Leu Leu Ala Arg 
    610                 615                 620                 


Lys Asp Ser Glu Thr Gly Glu Asn Ile Arg Gln Ala Ala Ser Ser Leu 
625                 630                 635                 640 


Gln Gln Ala Ser Leu Lys Leu Phe Glu Met Ala Tyr Lys Lys Met Ala 
                645                 650                 655     


Ser Glu Arg Glu Gly Ser Gly Ser Ser Gly Thr Gly Glu Gln Lys Glu 
            660                 665                 670         


Asp Gln Lys Glu Glu Lys Gln 
        675                 


<210>  61
<211>  675
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  61

Met Ala Asp Lys Glu Ala Gly Gly Ser Asp Gly Pro Arg Glu Thr Ala 
1               5                   10                  15      


Pro Thr Ser Ala Tyr Ser Ser Pro Ala Arg Ser Leu Gly Asp Thr Gly 
            20                  25                  30          


Ile Thr Pro Leu Ser Pro Ser His Ile Val Asn Asp Thr Asp Ser Asn 
        35                  40                  45              


Val Ser Glu Gln Gln Ser Phe Leu Val Val Val Ala Val Asp Phe Gly 
    50                  55                  60                  


Thr Thr Ser Ser Gly Tyr Ala Tyr Ser Phe Thr Lys Glu Pro Glu Cys 
65                  70                  75                  80  


Ile His Val Met Arg Arg Trp Glu Gly Gly Asp Pro Gly Val Ser Asn 
                85                  90                  95      


Gln Lys Thr Pro Thr Thr Ile Leu Leu Thr Pro Glu Arg Lys Phe His 
            100                 105                 110         


Ser Phe Gly Tyr Ala Ala Arg Asp Phe Tyr His Asp Leu Asp Pro Asn 
        115                 120                 125             


Glu Ala Lys Gln Trp Leu Tyr Leu Glu Lys Phe Lys Met Lys Leu His 
    130                 135                 140                 


Thr Thr Gly Asp Leu Thr Met Asp Thr Asp Leu Thr Ala Ala Asn Gly 
145                 150                 155                 160 


Lys Lys Val Lys Ala Leu Glu Ile Phe Ala Tyr Ala Leu Gln Tyr Phe 
                165                 170                 175     


Lys Glu Gln Ala Leu Lys Glu Leu Ser Asp Gln Ala Gly Ser Glu Phe 
            180                 185                 190         


Glu Asn Ser Asp Val Arg Trp Val Ile Thr Val Pro Ala Ile Trp Lys 
        195                 200                 205             


Gln Pro Ala Lys Gln Phe Met Arg Gln Ala Ala Tyr Gln Ala Gly Leu 
    210                 215                 220                 


Ala Ser Pro Glu Asn Ser Glu Gln Leu Ile Ile Ala Leu Glu Pro Glu 
225                 230                 235                 240 


Ala Ala Ser Ile Tyr Cys Arg Lys Leu Arg Leu His Gln Met Ile Glu 
                245                 250                 255     


Leu Ser Ser Lys Ala Ala Val Asn Gly Tyr Ser Gly Ser Asp Thr Val 
            260                 265                 270         


Gly Ala Gly Phe Thr Gln Ala Lys Glu His Ile Arg Arg Asn Arg Gln 
        275                 280                 285             


Ser Arg Thr Phe Leu Val Glu Asn Val Ile Gly Glu Ile Trp Ser Glu 
    290                 295                 300                 


Leu Glu Glu Gly Asp Lys Tyr Val Val Val Asp Ser Gly Gly Gly Thr 
305                 310                 315                 320 


Val Asp Leu Thr Val His Gln Ile Arg Leu Pro Glu Gly His Leu Lys 
                325                 330                 335     


Glu Leu Tyr Lys Ala Thr Gly Gly Pro Tyr Gly Ser Leu Gly Val Asp 
            340                 345                 350         


Tyr Glu Phe Glu Lys Leu Leu Tyr Lys Ile Phe Gly Glu Asp Phe Ile 
        355                 360                 365             


Glu Gln Phe Lys Ile Lys Arg Pro Ala Ala Trp Val Asp Leu Met Ile 
    370                 375                 380                 


Ala Phe Glu Ser Arg Lys Arg Ala Ala Ala Pro Asp Arg Thr Asn Pro 
385                 390                 395                 400 


Leu Asn Ile Thr Leu Pro Phe Ser Phe Ile Asp Tyr Tyr Lys Lys Phe 
                405                 410                 415     


Arg Gly His Ser Val Glu His Ala Leu Arg Lys Ser Asn Val Asp Phe 
            420                 425                 430         


Val Lys Trp Ser Ser Gln Gly Met Leu Arg Met Ser Pro Asp Ala Met 
        435                 440                 445             


Asn Ala Leu Phe Lys Pro Thr Ile Asp Ser Ile Ile Glu His Leu Arg 
    450                 455                 460                 


Asp Leu Phe Gln Lys Pro Glu Val Ser Thr Val Lys Phe Leu Phe Leu 
465                 470                 475                 480 


Val Gly Gly Phe Ala Glu Ala Pro Leu Leu Gln Gln Ala Val Gln Ala 
                485                 490                 495     


Ala Phe Gly Asp Gln Cys Arg Ile Ile Ile Pro Gln Asp Val Gly Leu 
            500                 505                 510         


Thr Ile Leu Lys Gly Ala Val Leu Phe Gly Leu Asp Pro Ala Val Ile 
        515                 520                 525             


Lys Val Arg Arg Ser Pro Leu Thr Tyr Gly Val Gly Val Leu Asn Arg 
    530                 535                 540                 


Tyr Val Glu Gly Lys His Pro Pro Glu Lys Leu Leu Val Lys Asp Gly 
545                 550                 555                 560 


Thr Arg Trp Cys Thr Asp Val Phe Asp Lys Phe Ile Ser Ala Asp Gln 
                565                 570                 575     


Ser Val Ala Leu Gly Glu Leu Val Lys Arg Ser Tyr Thr Pro Ala Lys 
            580                 585                 590         


Pro Ser Gln Leu Val Ile Val Ile Asn Ile Tyr Ser Ser Glu His Asp 
        595                 600                 605             


Asn Val Ser Phe Ile Thr Asp Pro Gly Val Lys Lys Cys Gly Thr Leu 
    610                 615                 620                 


Arg Leu Asp Leu Thr Gly Thr Ser Gly Thr Ala Val Pro Ala Arg Arg 
625                 630                 635                 640 


Glu Ile Gln Thr Leu Met Gln Phe Gly Asp Thr Glu Ile Lys Ala Thr 
                645                 650                 655     


Ala Ile Asp Ile Ala Thr Ser Lys Ser Val Lys Val Gly Ile Asp Phe 
            660                 665                 670         


Leu Asn Tyr 
        675 


<210>  62
<211>  686
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  62

Met Leu Ala Val Pro Glu Met Gly Leu Gln Gly Leu Tyr Ile Gly Ser 
1               5                   10                  15      


Ser Pro Glu Arg Ser Pro Val Pro Ser Pro Pro Gly Ser Pro Arg Thr 
            20                  25                  30          


Gln Glu Ser Cys Gly Ile Ala Pro Leu Thr Pro Ser Gln Ser Pro Lys 
        35                  40                  45              


Pro Glu Val Arg Ala Pro Gln Gln Ala Ser Phe Ser Val Val Val Ala 
    50                  55                  60                  


Ile Asp Phe Gly Thr Thr Ser Ser Gly Tyr Ala Phe Ser Phe Ala Ser 
65                  70                  75                  80  


Asp Pro Glu Ala Ile His Met Met Arg Lys Trp Glu Gly Gly Asp Pro 
                85                  90                  95      


Gly Val Ala His Gln Lys Thr Pro Thr Cys Leu Leu Leu Thr Pro Glu 
            100                 105                 110         


Gly Ala Phe His Ser Phe Gly Tyr Thr Ala Arg Asp Tyr Tyr His Asp 
        115                 120                 125             


Leu Asp Pro Glu Glu Ala Arg Asp Trp Leu Tyr Phe Glu Lys Phe Lys 
    130                 135                 140                 


Met Lys Ile His Ser Ala Thr Asp Leu Thr Leu Lys Thr Gln Leu Glu 
145                 150                 155                 160 


Ala Val Asn Gly Lys Thr Met Pro Ala Leu Glu Val Phe Ala His Ala 
                165                 170                 175     


Leu Arg Phe Phe Arg Glu His Ala Leu Gln Glu Leu Arg Glu Gln Ser 
            180                 185                 190         


Pro Ser Leu Pro Glu Lys Asp Thr Val Arg Trp Val Leu Thr Val Pro 
        195                 200                 205             


Ala Ile Trp Lys Gln Pro Ala Lys Gln Phe Met Arg Glu Ala Ala Tyr 
    210                 215                 220                 


Leu Ala Gly Leu Val Ser Arg Glu Asn Ala Glu Gln Leu Leu Ile Ala 
225                 230                 235                 240 


Leu Glu Pro Glu Ala Ala Ser Val Tyr Cys Arg Lys Leu Arg Leu His 
                245                 250                 255     


Gln Leu Leu Asp Leu Ser Gly Arg Ala Pro Gly Gly Gly Arg Leu Gly 
            260                 265                 270         


Glu Arg Arg Ser Ile Asp Ser Ser Phe Arg Gln Ala Arg Glu Gln Leu 
        275                 280                 285             


Arg Arg Ser Arg His Ser Arg Thr Phe Leu Val Glu Ser Gly Val Gly 
    290                 295                 300                 


Glu Leu Trp Ala Glu Met Gln Ala Gly Asp Arg Tyr Val Val Ala Asp 
305                 310                 315                 320 


Cys Gly Gly Gly Thr Val Asp Leu Thr Val His Gln Leu Glu Gln Pro 
                325                 330                 335     


His Gly Thr Leu Lys Glu Leu Tyr Lys Ala Ser Gly Gly Pro Tyr Gly 
            340                 345                 350         


Ala Val Gly Val Asp Leu Ala Phe Glu Gln Leu Leu Cys Arg Ile Phe 
        355                 360                 365             


Gly Glu Asp Phe Ile Ala Thr Phe Lys Arg Gln Arg Pro Ala Ala Trp 
    370                 375                 380                 


Val Asp Leu Thr Ile Ala Phe Glu Ala Arg Lys Arg Thr Ala Gly Pro 
385                 390                 395                 400 


His Arg Ala Gly Ala Leu Asn Ile Ser Leu Pro Phe Ser Phe Ile Asp 
                405                 410                 415     


Phe Tyr Arg Lys Gln Arg Gly His Asn Val Glu Thr Ala Leu Arg Arg 
            420                 425                 430         


Ser Ser Val Asn Phe Val Lys Trp Ser Ser Gln Gly Met Leu Arg Met 
        435                 440                 445             


Ser Cys Glu Ala Met Asn Glu Leu Phe Gln Pro Thr Val Ser Gly Ile 
    450                 455                 460                 


Ile Gln His Ile Glu Ala Leu Leu Ala Arg Pro Glu Val Gln Gly Val 
465                 470                 475                 480 


Lys Leu Leu Phe Leu Val Gly Gly Phe Ala Glu Ser Ala Val Leu Gln 
                485                 490                 495     


His Ala Val Gln Ala Ala Leu Gly Ala Arg Gly Leu Arg Val Val Val 
            500                 505                 510         


Pro His Asp Val Gly Leu Thr Ile Leu Lys Gly Ala Val Leu Phe Gly 
        515                 520                 525             


Gln Ala Pro Gly Val Val Arg Val Arg Arg Ser Pro Leu Thr Tyr Gly 
    530                 535                 540                 


Val Gly Val Leu Asn Arg Phe Val Pro Gly Arg His Pro Pro Glu Lys 
545                 550                 555                 560 


Leu Leu Val Arg Asp Gly Arg Arg Trp Cys Thr Asp Val Phe Glu Arg 
                565                 570                 575     


Phe Val Ala Ala Glu Gln Ser Val Ala Leu Gly Glu Glu Val Arg Arg 
            580                 585                 590         


Ser Tyr Cys Pro Ala Arg Pro Gly Gln Arg Arg Val Leu Ile Asn Leu 
        595                 600                 605             


Tyr Cys Cys Ala Ala Glu Asp Ala Arg Phe Ile Thr Asp Pro Gly Val 
    610                 615                 620                 


Arg Lys Cys Gly Ala Leu Ser Leu Glu Leu Glu Pro Ala Asp Cys Gly 
625                 630                 635                 640 


Gln Asp Thr Ala Gly Ala Pro Pro Gly Arg Arg Glu Ile Arg Ala Ala 
                645                 650                 655     


Met Gln Phe Gly Asp Thr Glu Ile Lys Val Thr Ala Val Asp Val Ser 
            660                 665                 670         


Thr Asn Arg Ser Val Arg Ala Ser Ile Asp Phe Leu Ser Asn 
        675                 680                 685     


<210>  63
<211>  471
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  63

Met Ala Arg Glu Met Thr Ile Leu Gly Ser Ala Val Leu Thr Leu Leu 
1               5                   10                  15      


Leu Ala Gly Tyr Leu Ala Gln Gln Tyr Leu Pro Leu Pro Thr Pro Lys 
            20                  25                  30          


Val Ile Gly Ile Asp Leu Gly Thr Thr Tyr Cys Ser Val Gly Val Phe 
        35                  40                  45              


Phe Pro Gly Thr Gly Lys Val Lys Val Ile Pro Asp Glu Asn Gly His 
    50                  55                  60                  


Ile Ser Ile Pro Ser Met Val Ser Phe Thr Asp Asn Asp Val Tyr Val 
65                  70                  75                  80  


Gly Tyr Glu Ser Val Glu Leu Ala Asp Ser Asn Pro Gln Asn Thr Ile 
                85                  90                  95      


Tyr Asp Ala Lys Arg Phe Ile Gly Lys Ile Phe Thr Ala Glu Glu Leu 
            100                 105                 110         


Glu Ala Glu Ile Gly Arg Tyr Pro Phe Lys Val Leu Asn Lys Asn Gly 
        115                 120                 125             


Met Val Glu Phe Ser Val Thr Ser Asn Glu Thr Ile Thr Val Ser Pro 
    130                 135                 140                 


Glu Tyr Val Gly Ser Arg Leu Leu Leu Lys Leu Lys Glu Met Ala Glu 
145                 150                 155                 160 


Ala Tyr Leu Gly Met Pro Val Ala Asn Ala Val Ile Ser Val Pro Ala 
                165                 170                 175     


Glu Phe Asp Leu Lys Gln Arg Asn Ser Thr Ile Glu Ala Ala Asn Leu 
            180                 185                 190         


Ala Gly Leu Lys Ile Leu Arg Val Ile Asn Glu Pro Thr Ala Ala Ala 
        195                 200                 205             


Met Ala Tyr Gly Leu His Lys Ala Asp Val Phe His Val Leu Val Ile 
    210                 215                 220                 


Asp Leu Gly Gly Gly Thr Leu Asp Val Ser Leu Leu Asn Lys Gln Gly 
225                 230                 235                 240 


Gly Met Phe Leu Thr Arg Ala Met Ser Gly Asn Asn Lys Leu Gly Gly 
                245                 250                 255     


Gln Asp Phe Asn Gln Arg Leu Leu Gln Tyr Leu Tyr Lys Gln Ile Tyr 
            260                 265                 270         


Gln Thr Tyr Gly Phe Val Pro Ser Arg Lys Glu Glu Ile His Arg Leu 
        275                 280                 285             


Arg Gln Ala Val Glu Met Val Lys Leu Asn Leu Thr Leu His Gln Ser 
    290                 295                 300                 


Ala Gln Leu Ser Val Leu Leu Thr Val Glu Glu Gln Asp Arg Lys Glu 
305                 310                 315                 320 


Pro His Ser Ser Asp Thr Glu Leu Pro Lys Asp Lys Leu Ser Ser Ala 
                325                 330                 335     


Asp Asp His Arg Val Asn Ser Gly Phe Gly Arg Gly Leu Ser Asp Lys 
            340                 345                 350         


Lys Ser Gly Glu Ser Gln Val Leu Phe Glu Thr Glu Ile Ser Arg Lys 
        355                 360                 365             


Leu Phe Asp Thr Leu Asn Glu Asp Leu Phe Gln Lys Ile Leu Val Pro 
    370                 375                 380                 


Ile Gln Gln Val Leu Lys Glu Gly His Leu Glu Lys Thr Glu Ile Asp 
385                 390                 395                 400 


Glu Val Val Leu Val Gly Gly Ser Thr Arg Ile Pro Arg Ile Arg Gln 
                405                 410                 415     


Val Ile Gln Glu Phe Phe Gly Lys Asp Pro Asn Thr Ser Val Asp Pro 
            420                 425                 430         


Asp Leu Ala Val Val Thr Gly Val Ala Ile Gln Ala Gly Ile Asp Gly 
        435                 440                 445             


Gly Ser Trp Pro Leu Gln Val Ser Ala Leu Glu Ile Pro Asn Lys His 
    450                 455                 460                 


Leu Gln Lys Thr Asn Phe Asn 
465                 470     


<210>  64
<211>  509
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  64

Met Ala Ala Ile Gly Val His Leu Gly Cys Thr Ser Ala Cys Val Ala 
1               5                   10                  15      


Val Tyr Lys Asp Gly Arg Ala Gly Val Val Ala Asn Asp Ala Gly Asp 
            20                  25                  30          


Arg Val Thr Pro Ala Val Val Ala Tyr Ser Glu Asn Glu Glu Ile Val 
        35                  40                  45              


Gly Leu Ala Ala Lys Gln Ser Arg Ile Arg Asn Ile Ser Asn Thr Val 
    50                  55                  60                  


Met Lys Val Lys Gln Ile Leu Gly Arg Ser Ser Ser Asp Pro Gln Ala 
65                  70                  75                  80  


Gln Lys Tyr Ile Ala Glu Ser Lys Cys Leu Val Ile Glu Lys Asn Gly 
                85                  90                  95      


Lys Leu Arg Tyr Glu Ile Asp Thr Gly Glu Glu Thr Lys Phe Val Asn 
            100                 105                 110         


Pro Glu Asp Val Ala Arg Leu Ile Phe Ser Lys Met Lys Glu Thr Ala 
        115                 120                 125             


His Ser Val Leu Gly Ser Asp Ala Asn Asp Val Val Ile Thr Val Pro 
    130                 135                 140                 


Phe Asp Phe Gly Glu Lys Gln Lys Asn Ala Leu Gly Glu Ala Ala Arg 
145                 150                 155                 160 


Ala Ala Gly Phe Asn Val Leu Arg Leu Ile His Glu Pro Ser Ala Ala 
                165                 170                 175     


Leu Leu Ala Tyr Gly Ile Gly Gln Asp Ser Pro Thr Gly Lys Ser Asn 
            180                 185                 190         


Ile Leu Val Phe Lys Leu Gly Gly Thr Ser Leu Ser Leu Ser Val Met 
        195                 200                 205             


Glu Val Asn Ser Gly Ile Tyr Arg Val Leu Ser Thr Asn Thr Asp Asp 
    210                 215                 220                 


Asn Ile Gly Gly Ala His Phe Thr Glu Thr Leu Ala Gln Tyr Leu Ala 
225                 230                 235                 240 


Ser Glu Phe Gln Arg Ser Phe Lys His Asp Val Arg Gly Asn Ala Arg 
                245                 250                 255     


Ala Met Met Lys Leu Thr Asn Ser Ala Glu Val Ala Lys His Ser Leu 
            260                 265                 270         


Ser Thr Leu Gly Ser Ala Asn Cys Phe Leu Asp Ser Leu Tyr Glu Gly 
        275                 280                 285             


Gln Asp Phe Asp Cys Asn Val Ser Arg Ala Arg Phe Glu Leu Leu Cys 
    290                 295                 300                 


Ser Pro Leu Phe Asn Lys Cys Ile Glu Ala Ile Arg Gly Leu Leu Asp 
305                 310                 315                 320 


Gln Asn Gly Phe Thr Ala Asp Asp Ile Asn Lys Val Val Leu Cys Gly 
                325                 330                 335     


Gly Ser Ser Arg Ile Pro Lys Leu Gln Gln Leu Ile Lys Asp Leu Phe 
            340                 345                 350         


Pro Ala Val Glu Leu Leu Asn Ser Ile Pro Pro Asp Glu Val Ile Pro 
        355                 360                 365             


Ile Gly Ala Ala Ile Glu Ala Gly Ile Leu Ile Gly Lys Glu Asn Leu 
    370                 375                 380                 


Leu Val Glu Asp Ser Leu Met Ile Glu Cys Ser Ala Arg Asp Ile Leu 
385                 390                 395                 400 


Val Lys Gly Val Asp Glu Ser Gly Ala Ser Arg Phe Thr Val Leu Phe 
                405                 410                 415     


Pro Ser Gly Thr Pro Leu Pro Ala Arg Arg Gln His Thr Leu Gln Ala 
            420                 425                 430         


Pro Gly Ser Ile Ser Ser Val Cys Leu Glu Leu Tyr Glu Ser Asp Gly 
        435                 440                 445             


Lys Asn Ser Ala Lys Glu Glu Thr Lys Phe Ala Gln Val Val Leu Gln 
    450                 455                 460                 


Asp Leu Asp Lys Lys Glu Asn Gly Leu Arg Asp Ile Leu Ala Val Leu 
465                 470                 475                 480 


Thr Met Lys Arg Asp Gly Ser Leu His Val Thr Cys Thr Asp Gln Glu 
                485                 490                 495     


Thr Gly Lys Cys Glu Ala Ile Ser Ile Glu Ile Ala Ser 
            500                 505                 


<210>  65
<211>  858
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  65

Met Ser Val Val Gly Leu Asp Val Gly Ser Gln Ser Cys Tyr Ile Ala 
1               5                   10                  15      


Val Ala Arg Ala Gly Gly Ile Glu Thr Ile Ala Asn Glu Phe Ser Asp 
            20                  25                  30          


Arg Cys Thr Pro Ser Val Ile Ser Phe Gly Ser Lys Asn Arg Thr Ile 
        35                  40                  45              


Gly Val Ala Ala Lys Asn Gln Gln Ile Thr His Ala Asn Asn Thr Val 
    50                  55                  60                  


Ser Asn Phe Lys Arg Phe His Gly Arg Ala Phe Asn Asp Pro Phe Ile 
65                  70                  75                  80  


Gln Lys Glu Lys Glu Asn Leu Ser Tyr Asp Leu Val Pro Leu Lys Asn 
                85                  90                  95      


Gly Gly Val Gly Ile Lys Val Met Tyr Met Gly Glu Glu His Leu Phe 
            100                 105                 110         


Ser Val Glu Gln Ile Thr Ala Met Leu Leu Thr Lys Leu Lys Glu Thr 
        115                 120                 125             


Ala Glu Asn Ser Leu Lys Lys Pro Val Thr Asp Cys Val Ile Ser Val 
    130                 135                 140                 


Pro Ser Phe Phe Thr Asp Ala Glu Arg Arg Ser Val Leu Asp Ala Ala 
145                 150                 155                 160 


Gln Ile Val Gly Leu Asn Cys Leu Arg Leu Met Asn Asp Met Thr Ala 
                165                 170                 175     


Val Ala Leu Asn Tyr Gly Ile Tyr Lys Gln Asp Leu Pro Ser Leu Asp 
            180                 185                 190         


Glu Lys Pro Arg Ile Val Val Phe Val Asp Met Gly His Ser Ala Phe 
        195                 200                 205             


Gln Val Ser Ala Cys Ala Phe Asn Lys Gly Lys Leu Lys Val Leu Gly 
    210                 215                 220                 


Thr Ala Phe Asp Pro Phe Leu Gly Gly Lys Asn Phe Asp Glu Lys Leu 
225                 230                 235                 240 


Val Glu His Phe Cys Ala Glu Phe Lys Thr Lys Tyr Lys Leu Asp Ala 
                245                 250                 255     


Lys Ser Lys Ile Arg Ala Leu Leu Arg Leu Tyr Gln Glu Cys Glu Lys 
            260                 265                 270         


Leu Lys Lys Leu Met Ser Ser Asn Ser Thr Asp Leu Pro Leu Asn Ile 
        275                 280                 285             


Glu Cys Phe Met Asn Asp Lys Asp Val Ser Gly Lys Met Asn Arg Ser 
    290                 295                 300                 


Gln Phe Glu Glu Leu Cys Ala Glu Leu Leu Gln Lys Ile Glu Val Pro 
305                 310                 315                 320 


Leu Tyr Ser Leu Leu Glu Gln Thr His Leu Lys Val Glu Asp Val Ser 
                325                 330                 335     


Ala Val Glu Ile Val Gly Gly Ala Thr Arg Ile Pro Ala Val Lys Glu 
            340                 345                 350         


Arg Ile Ala Lys Phe Phe Gly Lys Asp Ile Ser Thr Thr Leu Asn Ala 
        355                 360                 365             


Asp Glu Ala Val Ala Arg Gly Cys Ala Leu Gln Cys Ala Ile Leu Ser 
    370                 375                 380                 


Pro Ala Phe Lys Val Arg Glu Phe Ser Val Thr Asp Ala Val Pro Phe 
385                 390                 395                 400 


Pro Ile Ser Leu Ile Trp Asn His Asp Ser Glu Asp Thr Glu Gly Val 
                405                 410                 415     


His Glu Val Phe Ser Arg Asn His Ala Ala Pro Phe Ser Lys Val Leu 
            420                 425                 430         


Thr Phe Leu Arg Arg Gly Pro Phe Glu Leu Glu Ala Phe Tyr Ser Asp 
        435                 440                 445             


Pro Gln Gly Val Pro Tyr Pro Glu Ala Lys Ile Gly Arg Phe Val Val 
    450                 455                 460                 


Gln Asn Val Ser Ala Gln Lys Asp Gly Glu Lys Ser Arg Val Lys Val 
465                 470                 475                 480 


Lys Val Arg Val Asn Thr His Gly Ile Phe Thr Ile Ser Thr Ala Ser 
                485                 490                 495     


Met Val Glu Lys Val Pro Thr Glu Glu Asn Glu Met Ser Ser Glu Ala 
            500                 505                 510         


Asp Met Glu Cys Leu Asn Gln Arg Pro Pro Glu Asn Pro Asp Thr Asp 
        515                 520                 525             


Lys Asn Val Gln Gln Asp Asn Ser Glu Ala Gly Thr Gln Pro Gln Val 
    530                 535                 540                 


Gln Thr Asp Ala Gln Gln Thr Ser Gln Ser Pro Pro Ser Pro Glu Leu 
545                 550                 555                 560 


Thr Ser Glu Glu Asn Lys Ile Pro Asp Ala Asp Lys Ala Asn Glu Lys 
                565                 570                 575     


Lys Val Asp Gln Pro Pro Glu Ala Lys Lys Pro Lys Ile Lys Val Val 
            580                 585                 590         


Asn Val Glu Leu Pro Ile Glu Ala Asn Leu Val Trp Gln Leu Gly Lys 
        595                 600                 605             


Asp Leu Leu Asn Met Tyr Ile Glu Thr Glu Gly Lys Met Ile Met Gln 
    610                 615                 620                 


Asp Lys Leu Glu Lys Glu Arg Asn Asp Ala Lys Asn Ala Val Glu Glu 
625                 630                 635                 640 


Tyr Val Tyr Glu Phe Arg Asp Lys Leu Cys Gly Pro Tyr Glu Lys Phe 
                645                 650                 655     


Ile Cys Glu Gln Asp His Gln Asn Phe Leu Arg Leu Leu Thr Glu Thr 
            660                 665                 670         


Glu Asp Trp Leu Tyr Glu Glu Gly Glu Asp Gln Ala Lys Gln Ala Tyr 
        675                 680                 685             


Val Asp Lys Leu Glu Glu Leu Met Lys Ile Gly Thr Pro Val Lys Val 
    690                 695                 700                 


Arg Phe Gln Glu Ala Glu Glu Arg Pro Lys Met Phe Glu Glu Leu Gly 
705                 710                 715                 720 


Gln Arg Leu Gln His Tyr Ala Lys Ile Ala Ala Asp Phe Arg Asn Lys 
                725                 730                 735     


Asp Glu Lys Tyr Asn His Ile Asp Glu Ser Glu Met Lys Lys Val Glu 
            740                 745                 750         


Lys Ser Val Asn Glu Val Met Glu Trp Met Asn Asn Val Met Asn Ala 
        755                 760                 765             


Gln Ala Lys Lys Ser Leu Asp Gln Asp Pro Val Val Arg Ala Gln Glu 
    770                 775                 780                 


Ile Lys Thr Lys Ile Lys Glu Leu Asn Asn Thr Cys Glu Pro Val Val 
785                 790                 795                 800 


Thr Gln Pro Lys Pro Lys Ile Glu Ser Pro Lys Leu Glu Arg Thr Pro 
                805                 810                 815     


Asn Gly Pro Asn Ile Asp Lys Lys Glu Glu Asp Leu Glu Asp Lys Asn 
            820                 825                 830         


Asn Phe Gly Ala Glu Pro Pro His Gln Asn Gly Glu Cys Tyr Pro Asn 
        835                 840                 845             


Glu Lys Asn Ser Val Asn Met Asp Leu Asp 
    850                 855             


<210>  66
<211>  999
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  66

Met Ala Asp Lys Val Arg Arg Gln Arg Pro Arg Arg Arg Val Cys Trp 
1               5                   10                  15      


Ala Leu Val Ala Val Leu Leu Ala Asp Leu Leu Ala Leu Ser Asp Thr 
            20                  25                  30          


Leu Ala Val Met Ser Val Asp Leu Gly Ser Glu Ser Met Lys Val Ala 
        35                  40                  45              


Ile Val Lys Pro Gly Val Pro Met Glu Ile Val Leu Asn Lys Glu Ser 
    50                  55                  60                  


Arg Arg Lys Thr Pro Val Ile Val Thr Leu Lys Glu Asn Glu Arg Phe 
65                  70                  75                  80  


Phe Gly Asp Ser Ala Ala Ser Met Ala Ile Lys Asn Pro Lys Ala Thr 
                85                  90                  95      


Leu Arg Tyr Phe Gln His Leu Leu Gly Lys Gln Ala Asp Asn Pro His 
            100                 105                 110         


Val Ala Leu Tyr Gln Ala Arg Phe Pro Glu His Glu Leu Thr Phe Asp 
        115                 120                 125             


Pro Gln Arg Gln Thr Val His Phe Gln Ile Ser Ser Gln Leu Gln Phe 
    130                 135                 140                 


Ser Pro Glu Glu Val Leu Gly Met Val Leu Asn Tyr Ser Arg Ser Leu 
145                 150                 155                 160 


Ala Glu Asp Phe Ala Glu Gln Pro Ile Lys Asp Ala Val Ile Thr Val 
                165                 170                 175     


Pro Val Phe Phe Asn Gln Ala Glu Arg Arg Ala Val Leu Gln Ala Ala 
            180                 185                 190         


Arg Met Ala Gly Leu Lys Val Leu Gln Leu Ile Asn Asp Asn Thr Ala 
        195                 200                 205             


Thr Ala Leu Ser Tyr Gly Val Phe Arg Arg Lys Asp Ile Asn Thr Thr 
    210                 215                 220                 


Ala Gln Asn Ile Met Phe Tyr Asp Met Gly Ser Gly Ser Thr Val Cys 
225                 230                 235                 240 


Thr Ile Val Thr Tyr Gln Met Val Lys Thr Lys Glu Ala Gly Met Gln 
                245                 250                 255     


Pro Gln Leu Gln Ile Arg Gly Val Gly Phe Asp Arg Thr Leu Gly Gly 
            260                 265                 270         


Leu Glu Met Glu Leu Arg Leu Arg Glu Arg Leu Ala Gly Leu Phe Asn 
        275                 280                 285             


Glu Gln Arg Lys Gly Gln Arg Ala Lys Asp Val Arg Glu Asn Pro Arg 
    290                 295                 300                 


Ala Met Ala Lys Leu Leu Arg Glu Ala Asn Arg Leu Lys Thr Val Leu 
305                 310                 315                 320 


Ser Ala Asn Ala Asp His Met Ala Gln Ile Glu Gly Leu Met Asp Asp 
                325                 330                 335     


Val Asp Phe Lys Ala Lys Val Thr Arg Val Glu Phe Glu Glu Leu Cys 
            340                 345                 350         


Ala Asp Leu Phe Glu Arg Val Pro Gly Pro Val Gln Gln Ala Leu Gln 
        355                 360                 365             


Ser Ala Glu Met Ser Leu Asp Glu Ile Glu Gln Val Ile Leu Val Gly 
    370                 375                 380                 


Gly Ala Thr Arg Val Pro Arg Val Gln Glu Val Leu Leu Lys Ala Val 
385                 390                 395                 400 


Gly Lys Glu Glu Leu Gly Lys Asn Ile Asn Ala Asp Glu Ala Ala Ala 
                405                 410                 415     


Met Gly Ala Val Tyr Gln Ala Ala Ala Leu Ser Lys Ala Phe Lys Val 
            420                 425                 430         


Lys Pro Phe Val Val Arg Asp Ala Val Val Tyr Pro Ile Leu Val Glu 
        435                 440                 445             


Phe Thr Arg Glu Val Glu Glu Glu Pro Gly Ile His Ser Leu Lys His 
    450                 455                 460                 


Asn Lys Arg Val Leu Phe Ser Arg Met Gly Pro Tyr Pro Gln Arg Lys 
465                 470                 475                 480 


Val Ile Thr Phe Asn Arg Tyr Ser His Asp Phe Asn Phe His Ile Asn 
                485                 490                 495     


Tyr Gly Asp Leu Gly Phe Leu Gly Pro Glu Asp Leu Arg Val Phe Gly 
            500                 505                 510         


Ser Gln Asn Leu Thr Thr Val Lys Leu Lys Gly Val Gly Asp Ser Phe 
        515                 520                 525             


Lys Lys Tyr Pro Asp Tyr Glu Ser Lys Gly Ile Lys Ala His Phe Asn 
    530                 535                 540                 


Leu Asp Glu Ser Gly Val Leu Ser Leu Asp Arg Val Glu Ser Val Phe 
545                 550                 555                 560 


Glu Thr Leu Val Glu Asp Ser Ala Glu Glu Glu Ser Thr Leu Thr Lys 
                565                 570                 575     


Leu Gly Asn Thr Ile Ser Ser Leu Phe Gly Gly Gly Thr Thr Pro Asp 
            580                 585                 590         


Ala Lys Glu Asn Gly Thr Asp Thr Val Gln Glu Glu Glu Glu Ser Pro 
        595                 600                 605             


Ala Glu Gly Ser Lys Asp Glu Pro Gly Glu Gln Val Glu Leu Lys Glu 
    610                 615                 620                 


Glu Ala Glu Ala Pro Val Glu Asp Gly Ser Gln Pro Pro Pro Pro Glu 
625                 630                 635                 640 


Pro Lys Gly Asp Ala Thr Pro Glu Gly Glu Lys Ala Thr Glu Lys Glu 
                645                 650                 655     


Asn Gly Asp Lys Ser Glu Ala Gln Lys Pro Ser Glu Lys Ala Glu Ala 
            660                 665                 670         


Gly Pro Glu Gly Val Ala Pro Ala Pro Glu Gly Glu Lys Lys Gln Lys 
        675                 680                 685             


Pro Ala Arg Lys Arg Arg Met Val Glu Glu Ile Gly Val Glu Leu Val 
    690                 695                 700                 


Val Leu Asp Leu Pro Asp Leu Pro Glu Asp Lys Leu Ala Gln Ser Val 
705                 710                 715                 720 


Gln Lys Leu Gln Asp Leu Thr Leu Arg Asp Leu Glu Lys Gln Glu Arg 
                725                 730                 735     


Glu Lys Ala Ala Asn Ser Leu Glu Ala Phe Ile Phe Glu Thr Gln Asp 
            740                 745                 750         


Lys Leu Tyr Gln Pro Glu Tyr Gln Glu Val Ser Thr Glu Glu Gln Arg 
        755                 760                 765             


Glu Glu Ile Ser Gly Lys Leu Ser Ala Ala Ser Thr Trp Leu Glu Asp 
    770                 775                 780                 


Glu Gly Val Gly Ala Thr Thr Val Met Leu Lys Glu Lys Leu Ala Glu 
785                 790                 795                 800 


Leu Arg Lys Leu Cys Gln Gly Leu Phe Phe Arg Val Glu Glu Arg Lys 
                805                 810                 815     


Lys Trp Pro Glu Arg Leu Ser Ala Leu Asp Asn Leu Leu Asn His Ser 
            820                 825                 830         


Ser Met Phe Leu Lys Gly Ala Arg Leu Ile Pro Glu Met Asp Gln Ile 
        835                 840                 845             


Phe Thr Glu Val Glu Met Thr Thr Leu Glu Lys Val Ile Asn Glu Thr 
    850                 855                 860                 


Trp Ala Trp Lys Asn Ala Thr Leu Ala Glu Gln Ala Lys Leu Pro Ala 
865                 870                 875                 880 


Thr Glu Lys Pro Val Leu Leu Ser Lys Asp Ile Glu Ala Lys Met Met 
                885                 890                 895     


Ala Leu Asp Arg Glu Val Gln Tyr Leu Leu Asn Lys Ala Lys Phe Thr 
            900                 905                 910         


Lys Pro Arg Pro Arg Pro Lys Asp Lys Asn Gly Thr Arg Ala Glu Pro 
        915                 920                 925             


Pro Leu Asn Ala Ser Ala Ser Asp Gln Gly Glu Lys Val Ile Pro Pro 
    930                 935                 940                 


Ala Gly Gln Thr Glu Asp Ala Glu Pro Ile Ser Glu Pro Glu Lys Val 
945                 950                 955                 960 


Glu Thr Gly Ser Glu Pro Gly Asp Thr Glu Pro Leu Glu Leu Gly Gly 
                965                 970                 975     


Pro Gly Ala Glu Pro Glu Gln Lys Glu Gln Ser Thr Gly Gln Lys Arg 
            980                 985                 990         


Pro Leu Lys Asn Asp Glu Leu 
        995                 


<210>  67
<211>  732
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  67

Met Pro Glu Glu Thr Gln Thr Gln Asp Gln Pro Met Glu Glu Glu Glu 
1               5                   10                  15      


Val Glu Thr Phe Ala Phe Gln Ala Glu Ile Ala Gln Leu Met Ser Leu 
            20                  25                  30          


Ile Ile Asn Thr Phe Tyr Ser Asn Lys Glu Ile Phe Leu Arg Glu Leu 
        35                  40                  45              


Ile Ser Asn Ser Ser Asp Ala Leu Asp Lys Ile Arg Tyr Glu Ser Leu 
    50                  55                  60                  


Thr Asp Pro Ser Lys Leu Asp Ser Gly Lys Glu Leu His Ile Asn Leu 
65                  70                  75                  80  


Ile Pro Asn Lys Gln Asp Arg Thr Leu Thr Ile Val Asp Thr Gly Ile 
                85                  90                  95      


Gly Met Thr Lys Ala Asp Leu Ile Asn Asn Leu Gly Thr Ile Ala Lys 
            100                 105                 110         


Ser Gly Thr Lys Ala Phe Met Glu Ala Leu Gln Ala Gly Ala Asp Ile 
        115                 120                 125             


Ser Met Ile Gly Gln Phe Gly Val Gly Phe Tyr Ser Ala Tyr Leu Val 
    130                 135                 140                 


Ala Glu Lys Val Thr Val Ile Thr Lys His Asn Asp Asp Glu Gln Tyr 
145                 150                 155                 160 


Ala Trp Glu Ser Ser Ala Gly Gly Ser Phe Thr Val Arg Thr Asp Thr 
                165                 170                 175     


Gly Glu Pro Met Gly Arg Gly Thr Lys Val Ile Leu His Leu Lys Glu 
            180                 185                 190         


Asp Gln Thr Glu Tyr Leu Glu Glu Arg Arg Ile Lys Glu Ile Val Lys 
        195                 200                 205             


Lys His Ser Gln Phe Ile Gly Tyr Pro Ile Thr Leu Phe Val Glu Lys 
    210                 215                 220                 


Glu Arg Asp Lys Glu Val Ser Asp Asp Glu Ala Glu Glu Lys Glu Asp 
225                 230                 235                 240 


Lys Glu Glu Glu Lys Glu Lys Glu Glu Lys Glu Ser Glu Asp Lys Pro 
                245                 250                 255     


Glu Ile Glu Asp Val Gly Ser Asp Glu Glu Glu Glu Lys Lys Asp Gly 
            260                 265                 270         


Asp Lys Lys Lys Lys Lys Lys Ile Lys Glu Lys Tyr Ile Asp Gln Glu 
        275                 280                 285             


Glu Leu Asn Lys Thr Lys Pro Ile Trp Thr Arg Asn Pro Asp Asp Ile 
    290                 295                 300                 


Thr Asn Glu Glu Tyr Gly Glu Phe Tyr Lys Ser Leu Thr Asn Asp Trp 
305                 310                 315                 320 


Glu Asp His Leu Ala Val Lys His Phe Ser Val Glu Gly Gln Leu Glu 
                325                 330                 335     


Phe Arg Ala Leu Leu Phe Val Pro Arg Arg Ala Pro Phe Asp Leu Phe 
            340                 345                 350         


Glu Asn Arg Lys Lys Lys Asn Asn Ile Lys Leu Tyr Val Arg Arg Val 
        355                 360                 365             


Phe Ile Met Asp Asn Cys Glu Glu Leu Ile Pro Glu Tyr Leu Asn Phe 
    370                 375                 380                 


Ile Arg Gly Val Val Asp Ser Glu Asp Leu Pro Leu Asn Ile Ser Arg 
385                 390                 395                 400 


Glu Met Leu Gln Gln Ser Lys Ile Leu Lys Val Ile Arg Lys Asn Leu 
                405                 410                 415     


Val Lys Lys Cys Leu Glu Leu Phe Thr Glu Leu Ala Glu Asp Lys Glu 
            420                 425                 430         


Asn Tyr Lys Lys Phe Tyr Glu Gln Phe Ser Lys Asn Ile Lys Leu Gly 
        435                 440                 445             


Ile His Glu Asp Ser Gln Asn Arg Lys Lys Leu Ser Glu Leu Leu Arg 
    450                 455                 460                 


Tyr Tyr Thr Ser Ala Ser Gly Asp Glu Met Val Ser Leu Lys Asp Tyr 
465                 470                 475                 480 


Cys Thr Arg Met Lys Glu Asn Gln Lys His Ile Tyr Tyr Ile Thr Gly 
                485                 490                 495     


Glu Thr Lys Asp Gln Val Ala Asn Ser Ala Phe Val Glu Arg Leu Arg 
            500                 505                 510         


Lys His Gly Leu Glu Val Ile Tyr Met Ile Glu Pro Ile Asp Glu Tyr 
        515                 520                 525             


Cys Val Gln Gln Leu Lys Glu Phe Glu Gly Lys Thr Leu Val Ser Val 
    530                 535                 540                 


Thr Lys Glu Gly Leu Glu Leu Pro Glu Asp Glu Glu Glu Lys Lys Lys 
545                 550                 555                 560 


Gln Glu Glu Lys Lys Thr Lys Phe Glu Asn Leu Cys Lys Ile Met Lys 
                565                 570                 575     


Asp Ile Leu Glu Lys Lys Val Glu Lys Val Val Val Ser Asn Arg Leu 
            580                 585                 590         


Val Thr Ser Pro Cys Cys Ile Val Thr Ser Thr Tyr Gly Trp Thr Ala 
        595                 600                 605             


Asn Met Glu Arg Ile Met Lys Ala Gln Ala Leu Arg Asp Asn Ser Thr 
    610                 615                 620                 


Met Gly Tyr Met Ala Ala Lys Lys His Leu Glu Ile Asn Pro Asp His 
625                 630                 635                 640 


Ser Ile Ile Glu Thr Leu Arg Gln Lys Ala Glu Ala Asp Lys Asn Asp 
                645                 650                 655     


Lys Ser Val Lys Asp Leu Val Ile Leu Leu Tyr Glu Thr Ala Leu Leu 
            660                 665                 670         


Ser Ser Gly Phe Ser Leu Glu Asp Pro Gln Thr His Ala Asn Arg Ile 
        675                 680                 685             


Tyr Arg Met Ile Lys Leu Gly Leu Gly Ile Asp Glu Asp Asp Pro Thr 
    690                 695                 700                 


Ala Asp Asp Thr Ser Ala Ala Val Thr Glu Glu Met Pro Pro Leu Glu 
705                 710                 715                 720 


Gly Asp Asp Asp Thr Ser Arg Met Glu Glu Val Asp 
                725                 730         


<210>  68
<211>  112
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NG_005218 __HsHSP90AA3P

<400>  68

Met Asp Ser Ser Lys Leu Asp Ser Gly Lys Gly Leu His Ile Asn Leu 
1               5                   10                  15      


Val Pro Asn Lys Gln Asn Gln Thr Leu Thr Ile Val Asp Thr Arg Ile 
            20                  25                  30          


Gly Met Thr Lys Thr Asp Leu Ile Asn Asn Leu Gly Thr Val Thr Lys 
        35                  40                  45              


Ser Gly Thr Lys Ala Phe Met Glu Ala Leu Gln Ala Asp Ala Asp Ile 
    50                  55                  60                  


Ser Met Ile Gly His Phe Gly Val Gly Phe Tyr Ser Ala Tyr Leu Val 
65                  70                  75                  80  


Ala Lys Lys Val Thr Val Ile Ser Lys His Asn Asn Asp Glu Gln Tyr 
                85                  90                  95      


Thr Trp Glu Ser Ser Ala Gly Gly Ser Phe Thr Val Arg Thr Asp Glu 
            100                 105                 110         


<210>  69
<211>  724
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  69

Met Pro Glu Glu Val His His Gly Glu Glu Glu Val Glu Thr Phe Ala 
1               5                   10                  15      


Phe Gln Ala Glu Ile Ala Gln Leu Met Ser Leu Ile Ile Asn Thr Phe 
            20                  25                  30          


Tyr Ser Asn Lys Glu Ile Phe Leu Arg Glu Leu Ile Ser Asn Ala Ser 
        35                  40                  45              


Asp Ala Leu Asp Lys Ile Arg Tyr Glu Ser Leu Thr Asp Pro Ser Lys 
    50                  55                  60                  


Leu Asp Ser Gly Lys Glu Leu Lys Ile Asp Ile Ile Pro Asn Pro Gln 
65                  70                  75                  80  


Glu Arg Thr Leu Thr Leu Val Asp Thr Gly Ile Gly Met Thr Lys Ala 
                85                  90                  95      


Asp Leu Ile Asn Asn Leu Gly Thr Ile Ala Lys Ser Gly Thr Lys Ala 
            100                 105                 110         


Phe Met Glu Ala Leu Gln Ala Gly Ala Asp Ile Ser Met Ile Gly Gln 
        115                 120                 125             


Phe Gly Val Gly Phe Tyr Ser Ala Tyr Leu Val Ala Glu Lys Val Val 
    130                 135                 140                 


Val Ile Thr Lys His Asn Asp Asp Glu Gln Tyr Ala Trp Glu Ser Ser 
145                 150                 155                 160 


Ala Gly Gly Ser Phe Thr Val Arg Ala Asp His Gly Glu Pro Ile Gly 
                165                 170                 175     


Arg Gly Thr Lys Val Ile Leu His Leu Lys Glu Asp Gln Thr Glu Tyr 
            180                 185                 190         


Leu Glu Glu Arg Arg Val Lys Glu Val Val Lys Lys His Ser Gln Phe 
        195                 200                 205             


Ile Gly Tyr Pro Ile Thr Leu Tyr Leu Glu Lys Glu Arg Glu Lys Glu 
    210                 215                 220                 


Ile Ser Asp Asp Glu Ala Glu Glu Glu Lys Gly Glu Lys Glu Glu Glu 
225                 230                 235                 240 


Asp Lys Asp Asp Glu Glu Lys Pro Lys Ile Glu Asp Val Gly Ser Asp 
                245                 250                 255     


Glu Glu Asp Asp Ser Gly Lys Asp Lys Lys Lys Lys Thr Lys Lys Ile 
            260                 265                 270         


Lys Glu Lys Tyr Ile Asp Gln Glu Glu Leu Asn Lys Thr Lys Pro Ile 
        275                 280                 285             


Trp Thr Arg Asn Pro Asp Asp Ile Thr Gln Glu Glu Tyr Gly Glu Phe 
    290                 295                 300                 


Tyr Lys Ser Leu Thr Asn Asp Trp Glu Asp His Leu Ala Val Lys His 
305                 310                 315                 320 


Phe Ser Val Glu Gly Gln Leu Glu Phe Arg Ala Leu Leu Phe Ile Pro 
                325                 330                 335     


Arg Arg Ala Pro Phe Asp Leu Phe Glu Asn Lys Lys Lys Lys Asn Asn 
            340                 345                 350         


Ile Lys Leu Tyr Val Arg Arg Val Phe Ile Met Asp Ser Cys Asp Glu 
        355                 360                 365             


Leu Ile Pro Glu Tyr Leu Asn Phe Ile Arg Gly Val Val Asp Ser Glu 
    370                 375                 380                 


Asp Leu Pro Leu Asn Ile Ser Arg Glu Met Leu Gln Gln Ser Lys Ile 
385                 390                 395                 400 


Leu Lys Val Ile Arg Lys Asn Ile Val Lys Lys Cys Leu Glu Leu Phe 
                405                 410                 415     


Ser Glu Leu Ala Glu Asp Lys Glu Asn Tyr Lys Lys Phe Tyr Glu Ala 
            420                 425                 430         


Phe Ser Lys Asn Leu Lys Leu Gly Ile His Glu Asp Ser Thr Asn Arg 
        435                 440                 445             


Arg Arg Leu Ser Glu Leu Leu Arg Tyr His Thr Ser Gln Ser Gly Asp 
    450                 455                 460                 


Glu Met Thr Ser Leu Ser Glu Tyr Val Ser Arg Met Lys Glu Thr Gln 
465                 470                 475                 480 


Lys Ser Ile Tyr Tyr Ile Thr Gly Glu Ser Lys Glu Gln Val Ala Asn 
                485                 490                 495     


Ser Ala Phe Val Glu Arg Val Arg Lys Arg Gly Phe Glu Val Val Tyr 
            500                 505                 510         


Met Thr Glu Pro Ile Asp Glu Tyr Cys Val Gln Gln Leu Lys Glu Phe 
        515                 520                 525             


Asp Gly Lys Ser Leu Val Ser Val Thr Lys Glu Gly Leu Glu Leu Pro 
    530                 535                 540                 


Glu Asp Glu Glu Glu Lys Lys Lys Met Glu Glu Ser Lys Ala Lys Phe 
545                 550                 555                 560 


Glu Asn Leu Cys Lys Leu Met Lys Glu Ile Leu Asp Lys Lys Val Glu 
                565                 570                 575     


Lys Val Thr Ile Ser Asn Arg Leu Val Ser Ser Pro Cys Cys Ile Val 
            580                 585                 590         


Thr Ser Thr Tyr Gly Trp Thr Ala Asn Met Glu Arg Ile Met Lys Ala 
        595                 600                 605             


Gln Ala Leu Arg Asp Asn Ser Thr Met Gly Tyr Met Met Ala Lys Lys 
    610                 615                 620                 


His Leu Glu Ile Asn Pro Asp His Pro Ile Val Glu Thr Leu Arg Gln 
625                 630                 635                 640 


Lys Ala Glu Ala Asp Lys Asn Asp Lys Ala Val Lys Asp Leu Val Val 
                645                 650                 655     


Leu Leu Phe Glu Thr Ala Leu Leu Ser Ser Gly Phe Ser Leu Glu Asp 
            660                 665                 670         


Pro Gln Thr His Ser Asn Arg Ile Tyr Arg Met Ile Lys Leu Gly Leu 
        675                 680                 685             


Gly Ile Asp Glu Asp Glu Val Ala Ala Glu Glu Pro Asn Ala Ala Val 
    690                 695                 700                 


Pro Asp Glu Ile Pro Pro Leu Glu Gly Asp Glu Asp Ala Ser Arg Met 
705                 710                 715                 720 


Glu Glu Val Asp 
                


<210>  70
<211>  803
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  70

Met Arg Ala Leu Trp Val Leu Gly Leu Cys Cys Val Leu Leu Thr Phe 
1               5                   10                  15      


Gly Ser Val Arg Ala Asp Asp Glu Val Asp Val Asp Gly Thr Val Glu 
            20                  25                  30          


Glu Asp Leu Gly Lys Ser Arg Glu Gly Ser Arg Thr Asp Asp Glu Val 
        35                  40                  45              


Val Gln Arg Glu Glu Glu Ala Ile Gln Leu Asp Gly Leu Asn Ala Ser 
    50                  55                  60                  


Gln Ile Arg Glu Leu Arg Glu Lys Ser Glu Lys Phe Ala Phe Gln Ala 
65                  70                  75                  80  


Glu Val Asn Arg Met Met Lys Leu Ile Ile Asn Ser Leu Tyr Lys Asn 
                85                  90                  95      


Lys Glu Ile Phe Leu Arg Glu Leu Ile Ser Asn Ala Ser Asp Ala Leu 
            100                 105                 110         


Asp Lys Ile Arg Leu Ile Ser Leu Thr Asp Glu Asn Ala Leu Ser Gly 
        115                 120                 125             


Asn Glu Glu Leu Thr Val Lys Ile Lys Cys Asp Lys Glu Lys Asn Leu 
    130                 135                 140                 


Leu His Val Thr Asp Thr Gly Val Gly Met Thr Arg Glu Glu Leu Val 
145                 150                 155                 160 


Lys Asn Leu Gly Thr Ile Ala Lys Ser Gly Thr Ser Glu Phe Leu Asn 
                165                 170                 175     


Lys Met Thr Glu Ala Gln Glu Asp Gly Gln Ser Thr Ser Glu Leu Ile 
            180                 185                 190         


Gly Gln Phe Gly Val Gly Phe Tyr Ser Ala Phe Leu Val Ala Asp Lys 
        195                 200                 205             


Val Ile Val Thr Ser Lys His Asn Asn Asp Thr Gln His Ile Trp Glu 
    210                 215                 220                 


Ser Asp Ser Asn Glu Phe Ser Val Ile Ala Asp Pro Arg Gly Asn Thr 
225                 230                 235                 240 


Leu Gly Arg Gly Thr Thr Ile Thr Leu Val Leu Lys Glu Glu Ala Ser 
                245                 250                 255     


Asp Tyr Leu Glu Leu Asp Thr Ile Lys Asn Leu Val Lys Lys Tyr Ser 
            260                 265                 270         


Gln Phe Ile Asn Phe Pro Ile Tyr Val Trp Ser Ser Lys Thr Glu Thr 
        275                 280                 285             


Val Glu Glu Pro Met Glu Glu Glu Glu Ala Ala Lys Glu Glu Lys Glu 
    290                 295                 300                 


Glu Ser Asp Asp Glu Ala Ala Val Glu Glu Glu Glu Glu Glu Lys Lys 
305                 310                 315                 320 


Pro Lys Thr Lys Lys Val Glu Lys Thr Val Trp Asp Trp Glu Leu Met 
                325                 330                 335     


Asn Asp Ile Lys Pro Ile Trp Gln Arg Pro Ser Lys Glu Val Glu Glu 
            340                 345                 350         


Asp Glu Tyr Lys Ala Phe Tyr Lys Ser Phe Ser Lys Glu Ser Asp Asp 
        355                 360                 365             


Pro Met Ala Tyr Ile His Phe Thr Ala Glu Gly Glu Val Thr Phe Lys 
    370                 375                 380                 


Ser Ile Leu Phe Val Pro Thr Ser Ala Pro Arg Gly Leu Phe Asp Glu 
385                 390                 395                 400 


Tyr Gly Ser Lys Lys Ser Asp Tyr Ile Lys Leu Tyr Val Arg Arg Val 
                405                 410                 415     


Phe Ile Thr Asp Asp Phe His Asp Met Met Pro Lys Tyr Leu Asn Phe 
            420                 425                 430         


Val Lys Gly Val Val Asp Ser Asp Asp Leu Pro Leu Asn Val Ser Arg 
        435                 440                 445             


Glu Thr Leu Gln Gln His Lys Leu Leu Lys Val Ile Arg Lys Lys Leu 
    450                 455                 460                 


Val Arg Lys Thr Leu Asp Met Ile Lys Lys Ile Ala Asp Asp Lys Tyr 
465                 470                 475                 480 


Asn Asp Thr Phe Trp Lys Glu Phe Gly Thr Asn Ile Lys Leu Gly Val 
                485                 490                 495     


Ile Glu Asp His Ser Asn Arg Thr Arg Leu Ala Lys Leu Leu Arg Phe 
            500                 505                 510         


Gln Ser Ser His His Pro Thr Asp Ile Thr Ser Leu Asp Gln Tyr Val 
        515                 520                 525             


Glu Arg Met Lys Glu Lys Gln Asp Lys Ile Tyr Phe Met Ala Gly Ser 
    530                 535                 540                 


Ser Arg Lys Glu Ala Glu Ser Ser Pro Phe Val Glu Arg Leu Leu Lys 
545                 550                 555                 560 


Lys Gly Tyr Glu Val Ile Tyr Leu Thr Glu Pro Val Asp Glu Tyr Cys 
                565                 570                 575     


Ile Gln Ala Leu Pro Glu Phe Asp Gly Lys Arg Phe Gln Asn Val Ala 
            580                 585                 590         


Lys Glu Gly Val Lys Phe Asp Glu Ser Glu Lys Thr Lys Glu Ser Arg 
        595                 600                 605             


Glu Ala Val Glu Lys Glu Phe Glu Pro Leu Leu Asn Trp Met Lys Asp 
    610                 615                 620                 


Lys Ala Leu Lys Asp Lys Ile Glu Lys Ala Val Val Ser Gln Arg Leu 
625                 630                 635                 640 


Thr Glu Ser Pro Cys Ala Leu Val Ala Ser Gln Tyr Gly Trp Ser Gly 
                645                 650                 655     


Asn Met Glu Arg Ile Met Lys Ala Gln Ala Tyr Gln Thr Gly Lys Asp 
            660                 665                 670         


Ile Ser Thr Asn Tyr Tyr Ala Ser Gln Lys Lys Thr Phe Glu Ile Asn 
        675                 680                 685             


Pro Arg His Pro Leu Ile Arg Asp Met Leu Arg Arg Ile Lys Glu Asp 
    690                 695                 700                 


Glu Asp Asp Lys Thr Val Leu Asp Leu Ala Val Val Leu Phe Glu Thr 
705                 710                 715                 720 


Ala Thr Leu Arg Ser Gly Tyr Leu Leu Pro Asp Thr Lys Ala Tyr Gly 
                725                 730                 735     


Asp Arg Ile Glu Arg Met Leu Arg Leu Ser Leu Asn Ile Asp Pro Asp 
            740                 745                 750         


Ala Lys Val Glu Glu Glu Pro Glu Glu Glu Pro Glu Glu Thr Ala Glu 
        755                 760                 765             


Asp Thr Thr Glu Asp Thr Glu Gln Asp Glu Asp Glu Glu Met Asp Val 
    770                 775                 780                 


Gly Thr Asp Glu Glu Glu Glu Thr Ala Lys Glu Ser Thr Ala Glu Lys 
785                 790                 795                 800 


Asp Glu Leu 
            


<210>  71
<211>  704
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  71

Met Ala Arg Glu Leu Arg Ala Leu Leu Leu Trp Gly Arg Arg Leu Arg 
1               5                   10                  15      


Pro Leu Leu Arg Ala Pro Ala Leu Ala Ala Val Pro Gly Gly Lys Pro 
            20                  25                  30          


Ile Leu Cys Pro Arg Arg Thr Thr Ala Gln Leu Gly Pro Arg Arg Asn 
        35                  40                  45              


Pro Ala Trp Ser Leu Gln Ala Gly Arg Leu Phe Ser Thr Gln Thr Ala 
    50                  55                  60                  


Glu Asp Lys Glu Glu Pro Leu His Ser Ile Ile Ser Ser Thr Glu Ser 
65                  70                  75                  80  


Val Gln Gly Ser Thr Ser Lys His Glu Phe Gln Ala Glu Thr Lys Lys 
                85                  90                  95      


Leu Leu Asp Ile Val Ala Arg Ser Leu Tyr Ser Glu Lys Glu Val Phe 
            100                 105                 110         


Ile Arg Glu Leu Ile Ser Asn Ala Ser Asp Ala Leu Glu Lys Leu Arg 
        115                 120                 125             


His Lys Leu Val Ser Asp Gly Gln Ala Leu Pro Glu Met Glu Ile His 
    130                 135                 140                 


Leu Gln Thr Asn Ala Glu Lys Gly Thr Ile Thr Ile Gln Asp Thr Gly 
145                 150                 155                 160 


Ile Gly Met Thr Gln Glu Glu Leu Val Ser Asn Leu Gly Thr Ile Ala 
                165                 170                 175     


Arg Ser Gly Ser Lys Ala Phe Leu Asp Ala Leu Gln Asn Gln Ala Glu 
            180                 185                 190         


Ala Ser Ser Lys Ile Ile Gly Gln Phe Gly Val Gly Phe Tyr Ser Ala 
        195                 200                 205             


Phe Met Val Ala Asp Arg Val Glu Val Tyr Ser Arg Ser Ala Ala Pro 
    210                 215                 220                 


Gly Ser Leu Gly Tyr Gln Trp Leu Ser Asp Gly Ser Gly Val Phe Glu 
225                 230                 235                 240 


Ile Ala Glu Ala Ser Gly Val Arg Thr Gly Thr Lys Ile Ile Ile His 
                245                 250                 255     


Leu Lys Ser Asp Cys Lys Glu Phe Ser Ser Glu Ala Arg Val Arg Asp 
            260                 265                 270         


Val Val Thr Lys Tyr Ser Asn Phe Val Ser Phe Pro Leu Tyr Leu Asn 
        275                 280                 285             


Gly Arg Arg Met Asn Thr Leu Gln Ala Ile Trp Met Met Asp Pro Lys 
    290                 295                 300                 


Asp Val Arg Glu Trp Gln His Glu Glu Phe Tyr Arg Tyr Val Ala Gln 
305                 310                 315                 320 


Ala His Asp Lys Pro Arg Tyr Thr Leu His Tyr Lys Thr Asp Ala Pro 
                325                 330                 335     


Leu Asn Ile Arg Ser Ile Phe Tyr Val Pro Asp Met Lys Pro Ser Met 
            340                 345                 350         


Phe Asp Val Ser Arg Glu Leu Gly Ser Ser Val Ala Leu Tyr Ser Arg 
        355                 360                 365             


Lys Val Leu Ile Gln Thr Lys Ala Thr Asp Ile Leu Pro Lys Trp Leu 
    370                 375                 380                 


Arg Phe Ile Arg Gly Val Val Asp Ser Glu Asp Ile Pro Leu Asn Leu 
385                 390                 395                 400 


Ser Arg Glu Leu Leu Gln Glu Ser Ala Leu Ile Arg Lys Leu Arg Asp 
                405                 410                 415     


Val Leu Gln Gln Arg Leu Ile Lys Phe Phe Ile Asp Gln Ser Lys Lys 
            420                 425                 430         


Asp Ala Glu Lys Tyr Ala Lys Phe Phe Glu Asp Tyr Gly Leu Phe Met 
        435                 440                 445             


Arg Glu Gly Ile Val Thr Ala Thr Glu Gln Glu Val Lys Glu Asp Ile 
    450                 455                 460                 


Ala Lys Leu Leu Arg Tyr Glu Ser Ser Ala Leu Pro Ser Gly Gln Leu 
465                 470                 475                 480 


Thr Ser Leu Ser Glu Tyr Ala Ser Arg Met Arg Ala Gly Thr Arg Asn 
                485                 490                 495     


Ile Tyr Tyr Leu Cys Ala Pro Asn Arg His Leu Ala Glu His Ser Pro 
            500                 505                 510         


Tyr Tyr Glu Ala Met Lys Lys Lys Asp Thr Glu Val Leu Phe Cys Phe 
        515                 520                 525             


Glu Gln Phe Asp Glu Leu Thr Leu Leu His Leu Arg Glu Phe Asp Lys 
    530                 535                 540                 


Lys Lys Leu Ile Ser Val Glu Thr Asp Ile Val Val Asp His Tyr Lys 
545                 550                 555                 560 


Glu Glu Lys Phe Glu Asp Arg Ser Pro Ala Ala Glu Cys Leu Ser Glu 
                565                 570                 575     


Lys Glu Thr Glu Glu Leu Met Ala Trp Met Arg Asn Val Leu Gly Ser 
            580                 585                 590         


Arg Val Thr Asn Val Lys Val Thr Leu Arg Leu Asp Thr His Pro Ala 
        595                 600                 605             


Met Val Thr Val Leu Glu Met Gly Ala Ala Arg His Phe Leu Arg Met 
    610                 615                 620                 


Gln Gln Leu Ala Lys Thr Gln Glu Glu Arg Ala Gln Leu Leu Gln Pro 
625                 630                 635                 640 


Thr Leu Glu Ile Asn Pro Arg His Ala Leu Ile Lys Lys Leu Asn Gln 
                645                 650                 655     


Leu Arg Ala Ser Glu Pro Gly Leu Ala Gln Leu Leu Val Asp Gln Ile 
            660                 665                 670         


Tyr Glu Asn Ala Met Ile Ala Ala Gly Leu Val Asp Asp Pro Arg Ala 
        675                 680                 685             


Met Val Gly Arg Leu Asn Glu Leu Leu Val Lys Ala Leu Glu Arg His 
    690                 695                 700                 


<210>  72
<211>  153
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  72

Met Gly Lys Ile Ser Ser Leu Pro Thr Gln Leu Phe Lys Cys Cys Phe 
1               5                   10                  15      


Cys Asp Phe Leu Lys Val Lys Met His Thr Met Ser Ser Ser His Leu 
            20                  25                  30          


Phe Tyr Leu Ala Leu Cys Leu Leu Thr Phe Thr Ser Ser Ala Thr Ala 
        35                  40                  45              


Gly Pro Glu Thr Leu Cys Gly Ala Glu Leu Val Asp Ala Leu Gln Phe 
    50                  55                  60                  


Val Cys Gly Asp Arg Gly Phe Tyr Phe Asn Lys Pro Thr Gly Tyr Gly 
65                  70                  75                  80  


Ser Ser Ser Arg Arg Ala Pro Gln Thr Gly Ile Val Asp Glu Cys Cys 
                85                  90                  95      


Phe Arg Ser Cys Asp Leu Arg Arg Leu Glu Met Tyr Cys Ala Pro Leu 
            100                 105                 110         


Lys Pro Ala Lys Ser Ala Arg Ser Val Arg Ala Gln Arg His Thr Asp 
        115                 120                 125             


Met Pro Lys Thr Gln Lys Glu Val His Leu Lys Asn Ala Ser Arg Gly 
    130                 135                 140                 


Ser Ala Gly Asn Lys Asn Tyr Arg Met 
145                 150             


<210>  73
<211>  180
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  73

Met Gly Ile Pro Met Gly Lys Ser Met Leu Val Leu Leu Thr Phe Leu 
1               5                   10                  15      


Ala Phe Ala Ser Cys Cys Ile Ala Ala Tyr Arg Pro Ser Glu Thr Leu 
            20                  25                  30          


Cys Gly Gly Glu Leu Val Asp Thr Leu Gln Phe Val Cys Gly Asp Arg 
        35                  40                  45              


Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser Arg Arg Ser Arg 
    50                  55                  60                  


Gly Ile Val Glu Glu Cys Cys Phe Arg Ser Cys Asp Leu Ala Leu Leu 
65                  70                  75                  80  


Glu Thr Tyr Cys Ala Thr Pro Ala Lys Ser Glu Arg Asp Val Ser Thr 
                85                  90                  95      


Pro Pro Thr Val Leu Pro Asp Asn Phe Pro Arg Tyr Pro Val Gly Lys 
            100                 105                 110         


Phe Phe Gln Tyr Asp Thr Trp Lys Gln Ser Thr Gln Arg Leu Arg Arg 
        115                 120                 125             


Gly Leu Pro Ala Leu Leu Arg Ala Arg Arg Gly His Val Leu Ala Lys 
    130                 135                 140                 


Glu Leu Glu Ala Phe Arg Glu Ala Lys Arg His Arg Pro Leu Ile Ala 
145                 150                 155                 160 


Leu Pro Thr Gln Asp Pro Ala His Gly Gly Ala Pro Pro Glu Met Ala 
                165                 170                 175     


Ser Asn Arg Lys 
            180 


<210>  74
<211>  212
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  74

Met Asn Ser Phe Ser Thr Ser Ala Phe Gly Pro Val Ala Phe Ser Leu 
1               5                   10                  15      


Gly Leu Leu Leu Val Leu Pro Ala Ala Phe Pro Ala Pro Val Pro Pro 
            20                  25                  30          


Gly Glu Asp Ser Lys Asp Val Ala Ala Pro His Arg Gln Pro Leu Thr 
        35                  40                  45              


Ser Ser Glu Arg Ile Asp Lys Gln Ile Arg Tyr Ile Leu Asp Gly Ile 
    50                  55                  60                  


Ser Ala Leu Arg Lys Glu Thr Cys Asn Lys Ser Asn Met Cys Glu Ser 
65                  70                  75                  80  


Ser Lys Glu Ala Leu Ala Glu Asn Asn Leu Asn Leu Pro Lys Met Ala 
                85                  90                  95      


Glu Lys Asp Gly Cys Phe Gln Ser Gly Phe Asn Glu Glu Thr Cys Leu 
            100                 105                 110         


Val Lys Ile Ile Thr Gly Leu Leu Glu Phe Glu Val Tyr Leu Glu Tyr 
        115                 120                 125             


Leu Gln Asn Arg Phe Glu Ser Ser Glu Glu Gln Ala Arg Ala Val Gln 
    130                 135                 140                 


Met Ser Thr Lys Val Leu Ile Gln Phe Leu Gln Lys Lys Ala Lys Asn 
145                 150                 155                 160 


Leu Asp Ala Ile Thr Thr Pro Asp Pro Thr Thr Asn Ala Ser Leu Leu 
                165                 170                 175     


Thr Lys Leu Gln Ala Gln Asn Gln Trp Leu Gln Asp Met Thr Thr His 
            180                 185                 190         


Leu Ile Leu Arg Ser Phe Lys Glu Phe Leu Gln Ser Ser Leu Arg Ala 
        195                 200                 205             


Leu Arg Gln Met 
    210         


<210>  75
<211>  426
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  75

Met Pro Leu Leu Trp Leu Arg Gly Phe Leu Leu Ala Ser Cys Trp Ile 
1               5                   10                  15      


Ile Val Arg Ser Ser Pro Thr Pro Gly Ser Glu Gly His Ser Ala Ala 
            20                  25                  30          


Pro Asp Cys Pro Ser Cys Ala Leu Ala Ala Leu Pro Lys Asp Val Pro 
        35                  40                  45              


Asn Ser Gln Pro Glu Met Val Glu Ala Val Lys Lys His Ile Leu Asn 
    50                  55                  60                  


Met Leu His Leu Lys Lys Arg Pro Asp Val Thr Gln Pro Val Pro Lys 
65                  70                  75                  80  


Ala Ala Leu Leu Asn Ala Ile Arg Lys Leu His Val Gly Lys Val Gly 
                85                  90                  95      


Glu Asn Gly Tyr Val Glu Ile Glu Asp Asp Ile Gly Arg Arg Ala Glu 
            100                 105                 110         


Met Asn Glu Leu Met Glu Gln Thr Ser Glu Ile Ile Thr Phe Ala Glu 
        115                 120                 125             


Ser Gly Thr Ala Arg Lys Thr Leu His Phe Glu Ile Ser Lys Glu Gly 
    130                 135                 140                 


Ser Asp Leu Ser Val Val Glu Arg Ala Glu Val Trp Leu Phe Leu Lys 
145                 150                 155                 160 


Val Pro Lys Ala Asn Arg Thr Arg Thr Lys Val Thr Ile Arg Leu Phe 
                165                 170                 175     


Gln Gln Gln Lys His Pro Gln Gly Ser Leu Asp Thr Gly Glu Glu Ala 
            180                 185                 190         


Glu Glu Val Gly Leu Lys Gly Glu Arg Ser Glu Leu Leu Leu Ser Glu 
        195                 200                 205             


Lys Val Val Asp Ala Arg Lys Ser Thr Trp His Val Phe Pro Val Ser 
    210                 215                 220                 


Ser Ser Ile Gln Arg Leu Leu Asp Gln Gly Lys Ser Ser Leu Asp Val 
225                 230                 235                 240 


Arg Ile Ala Cys Glu Gln Cys Gln Glu Ser Gly Ala Ser Leu Val Leu 
                245                 250                 255     


Leu Gly Lys Lys Lys Lys Lys Glu Glu Glu Gly Glu Gly Lys Lys Lys 
            260                 265                 270         


Gly Gly Gly Glu Gly Gly Ala Gly Ala Asp Glu Glu Lys Glu Gln Ser 
        275                 280                 285             


His Arg Pro Phe Leu Met Leu Gln Ala Arg Gln Ser Glu Asp His Pro 
    290                 295                 300                 


His Arg Arg Arg Arg Arg Gly Leu Glu Cys Asp Gly Lys Val Asn Ile 
305                 310                 315                 320 


Cys Cys Lys Lys Gln Phe Phe Val Ser Phe Lys Asp Ile Gly Trp Asn 
                325                 330                 335     


Asp Trp Ile Ile Ala Pro Ser Gly Tyr His Ala Asn Tyr Cys Glu Gly 
            340                 345                 350         


Glu Cys Pro Ser His Ile Ala Gly Thr Ser Gly Ser Ser Leu Ser Phe 
        355                 360                 365             


His Ser Thr Val Ile Asn His Tyr Arg Met Arg Gly His Ser Pro Phe 
    370                 375                 380                 


Ala Asn Leu Lys Ser Cys Cys Val Pro Thr Lys Leu Arg Pro Met Ser 
385                 390                 395                 400 


Met Leu Tyr Tyr Asp Asp Gly Gln Asn Ile Ile Lys Lys Asp Ile Gln 
                405                 410                 415     


Asn Met Ile Val Glu Glu Cys Gly Cys Ser 
            420                 425     


<210>  76
<211>  407
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  76

Met Asp Gly Leu Pro Gly Arg Ala Leu Gly Ala Ala Cys Leu Leu Leu 
1               5                   10                  15      


Leu Ala Ala Gly Trp Leu Gly Pro Glu Ala Trp Gly Ser Pro Thr Pro 
            20                  25                  30          


Pro Pro Thr Pro Ala Ala Pro Pro Pro Pro Pro Pro Pro Gly Ser Pro 
        35                  40                  45              


Gly Gly Ser Gln Asp Thr Cys Thr Ser Cys Gly Gly Phe Arg Arg Pro 
    50                  55                  60                  


Glu Glu Leu Gly Arg Val Asp Gly Asp Phe Leu Glu Ala Val Lys Arg 
65                  70                  75                  80  


His Ile Leu Ser Arg Leu Gln Met Arg Gly Arg Pro Asn Ile Thr His 
                85                  90                  95      


Ala Val Pro Lys Ala Ala Met Val Thr Ala Leu Arg Lys Leu His Ala 
            100                 105                 110         


Gly Lys Val Arg Glu Asp Gly Arg Val Glu Ile Pro His Leu Asp Gly 
        115                 120                 125             


His Ala Ser Pro Gly Ala Asp Gly Gln Glu Arg Val Ser Glu Ile Ile 
    130                 135                 140                 


Ser Phe Ala Glu Thr Asp Gly Leu Ala Ser Ser Arg Val Arg Leu Tyr 
145                 150                 155                 160 


Phe Phe Ile Ser Asn Glu Gly Asn Gln Asn Leu Phe Val Val Gln Ala 
                165                 170                 175     


Ser Leu Trp Leu Tyr Leu Lys Leu Leu Pro Tyr Val Leu Glu Lys Gly 
            180                 185                 190         


Ser Arg Arg Lys Val Arg Val Lys Val Tyr Phe Gln Glu Gln Gly His 
        195                 200                 205             


Gly Asp Arg Trp Asn Met Val Glu Lys Arg Val Asp Leu Lys Arg Ser 
    210                 215                 220                 


Gly Trp His Thr Phe Pro Leu Thr Glu Ala Ile Gln Ala Leu Phe Glu 
225                 230                 235                 240 


Arg Gly Glu Arg Arg Leu Asn Leu Asp Val Gln Cys Asp Ser Cys Gln 
                245                 250                 255     


Glu Leu Ala Val Val Pro Val Phe Val Asp Pro Gly Glu Glu Ser His 
            260                 265                 270         


Arg Pro Phe Val Val Val Gln Ala Arg Leu Gly Asp Ser Arg His Arg 
        275                 280                 285             


Ile Arg Lys Arg Gly Leu Glu Cys Asp Gly Arg Thr Asn Leu Cys Cys 
    290                 295                 300                 


Arg Gln Gln Phe Phe Ile Asp Phe Arg Leu Ile Gly Trp Asn Asp Trp 
305                 310                 315                 320 


Ile Ile Ala Pro Thr Gly Tyr Tyr Gly Asn Tyr Cys Glu Gly Ser Cys 
                325                 330                 335     


Pro Ala Tyr Leu Ala Gly Val Pro Gly Ser Ala Ser Ser Phe His Thr 
            340                 345                 350         


Ala Val Val Asn Gln Tyr Arg Met Arg Gly Leu Asn Pro Gly Thr Val 
        355                 360                 365             


Asn Ser Cys Cys Ile Pro Thr Lys Leu Ser Thr Met Ser Met Leu Tyr 
    370                 375                 380                 


Phe Asp Asp Glu Tyr Asn Ile Val Lys Arg Asp Val Pro Asn Met Ile 
385                 390                 395                 400 


Val Glu Glu Cys Gly Cys Ala 
                405         


<210>  77
<211>  1152
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  77

Met Ala Leu Arg Val Leu Leu Leu Thr Ala Leu Thr Leu Cys His Gly 
1               5                   10                  15      


Phe Asn Leu Asp Thr Glu Asn Ala Met Thr Phe Gln Glu Asn Ala Arg 
            20                  25                  30          


Gly Phe Gly Gln Ser Val Val Gln Leu Gln Gly Ser Arg Val Val Val 
        35                  40                  45              


Gly Ala Pro Gln Glu Ile Val Ala Ala Asn Gln Arg Gly Ser Leu Tyr 
    50                  55                  60                  


Gln Cys Asp Tyr Ser Thr Gly Ser Cys Glu Pro Ile Arg Leu Gln Val 
65                  70                  75                  80  


Pro Val Glu Ala Val Asn Met Ser Leu Gly Leu Ser Leu Ala Ala Thr 
                85                  90                  95      


Thr Ser Pro Pro Gln Leu Leu Ala Cys Gly Pro Thr Val His Gln Thr 
            100                 105                 110         


Cys Ser Glu Asn Thr Tyr Val Lys Gly Leu Cys Phe Leu Phe Gly Ser 
        115                 120                 125             


Asn Leu Arg Gln Gln Pro Gln Lys Phe Pro Glu Ala Leu Arg Gly Cys 
    130                 135                 140                 


Pro Gln Glu Asp Ser Asp Ile Ala Phe Leu Ile Asp Gly Ser Gly Ser 
145                 150                 155                 160 


Ile Ile Pro His Asp Phe Arg Arg Met Lys Glu Phe Val Ser Thr Val 
                165                 170                 175     


Met Glu Gln Leu Lys Lys Ser Lys Thr Leu Phe Ser Leu Met Gln Tyr 
            180                 185                 190         


Ser Glu Glu Phe Arg Ile His Phe Thr Phe Lys Glu Phe Gln Asn Asn 
        195                 200                 205             


Pro Asn Pro Arg Ser Leu Val Lys Pro Ile Thr Gln Leu Leu Gly Arg 
    210                 215                 220                 


Thr His Thr Ala Thr Gly Ile Arg Lys Val Val Arg Glu Leu Phe Asn 
225                 230                 235                 240 


Ile Thr Asn Gly Ala Arg Lys Asn Ala Phe Lys Ile Leu Val Val Ile 
                245                 250                 255     


Thr Asp Gly Glu Lys Phe Gly Asp Pro Leu Gly Tyr Glu Asp Val Ile 
            260                 265                 270         


Pro Glu Ala Asp Arg Glu Gly Val Ile Arg Tyr Val Ile Gly Val Gly 
        275                 280                 285             


Asp Ala Phe Arg Ser Glu Lys Ser Arg Gln Glu Leu Asn Thr Ile Ala 
    290                 295                 300                 


Ser Lys Pro Pro Arg Asp His Val Phe Gln Val Asn Asn Phe Glu Ala 
305                 310                 315                 320 


Leu Lys Thr Ile Gln Asn Gln Leu Arg Glu Lys Ile Phe Ala Ile Glu 
                325                 330                 335     


Gly Thr Gln Thr Gly Ser Ser Ser Ser Phe Glu His Glu Met Ser Gln 
            340                 345                 350         


Glu Gly Phe Ser Ala Ala Ile Thr Ser Asn Gly Pro Leu Leu Ser Thr 
        355                 360                 365             


Val Gly Ser Tyr Asp Trp Ala Gly Gly Val Phe Leu Tyr Thr Ser Lys 
    370                 375                 380                 


Glu Lys Ser Thr Phe Ile Asn Met Thr Arg Val Asp Ser Asp Met Asn 
385                 390                 395                 400 


Asp Ala Tyr Leu Gly Tyr Ala Ala Ala Ile Ile Leu Arg Asn Arg Val 
                405                 410                 415     


Gln Ser Leu Val Leu Gly Ala Pro Arg Tyr Gln His Ile Gly Leu Val 
            420                 425                 430         


Ala Met Phe Arg Gln Asn Thr Gly Met Trp Glu Ser Asn Ala Asn Val 
        435                 440                 445             


Lys Gly Thr Gln Ile Gly Ala Tyr Phe Gly Ala Ser Leu Cys Ser Val 
    450                 455                 460                 


Asp Val Asp Ser Asn Gly Ser Thr Asp Leu Val Leu Ile Gly Ala Pro 
465                 470                 475                 480 


His Tyr Tyr Glu Gln Thr Arg Gly Gly Gln Val Ser Val Cys Pro Leu 
                485                 490                 495     


Pro Arg Gly Arg Ala Arg Trp Gln Cys Asp Ala Val Leu Tyr Gly Glu 
            500                 505                 510         


Gln Gly Gln Pro Trp Gly Arg Phe Gly Ala Ala Leu Thr Val Leu Gly 
        515                 520                 525             


Asp Val Asn Gly Asp Lys Leu Thr Asp Val Ala Ile Gly Ala Pro Gly 
    530                 535                 540                 


Glu Glu Asp Asn Arg Gly Ala Val Tyr Leu Phe His Gly Thr Ser Gly 
545                 550                 555                 560 


Ser Gly Ile Ser Pro Ser His Ser Gln Arg Ile Ala Gly Ser Lys Leu 
                565                 570                 575     


Ser Pro Arg Leu Gln Tyr Phe Gly Gln Ser Leu Ser Gly Gly Gln Asp 
            580                 585                 590         


Leu Thr Met Asp Gly Leu Val Asp Leu Thr Val Gly Ala Gln Gly His 
        595                 600                 605             


Val Leu Leu Leu Arg Ser Gln Pro Val Leu Arg Val Lys Ala Ile Met 
    610                 615                 620                 


Glu Phe Asn Pro Arg Glu Val Ala Arg Asn Val Phe Glu Cys Asn Asp 
625                 630                 635                 640 


Gln Val Val Lys Gly Lys Glu Ala Gly Glu Val Arg Val Cys Leu His 
                645                 650                 655     


Val Gln Lys Ser Thr Arg Asp Arg Leu Arg Glu Gly Gln Ile Gln Ser 
            660                 665                 670         


Val Val Thr Tyr Asp Leu Ala Leu Asp Ser Gly Arg Pro His Ser Arg 
        675                 680                 685             


Ala Val Phe Asn Glu Thr Lys Asn Ser Thr Arg Arg Gln Thr Gln Val 
    690                 695                 700                 


Leu Gly Leu Thr Gln Thr Cys Glu Thr Leu Lys Leu Gln Leu Pro Asn 
705                 710                 715                 720 


Cys Ile Glu Asp Pro Val Ser Pro Ile Val Leu Arg Leu Asn Phe Ser 
                725                 730                 735     


Leu Val Gly Thr Pro Leu Ser Ala Phe Gly Asn Leu Arg Pro Val Leu 
            740                 745                 750         


Ala Glu Asp Ala Gln Arg Leu Phe Thr Ala Leu Phe Pro Phe Glu Lys 
        755                 760                 765             


Asn Cys Gly Asn Asp Asn Ile Cys Gln Asp Asp Leu Ser Ile Thr Phe 
    770                 775                 780                 


Ser Phe Met Ser Leu Asp Cys Leu Val Val Gly Gly Pro Arg Glu Phe 
785                 790                 795                 800 


Asn Val Thr Val Thr Val Arg Asn Asp Gly Glu Asp Ser Tyr Arg Thr 
                805                 810                 815     


Gln Val Thr Phe Phe Phe Pro Leu Asp Leu Ser Tyr Arg Lys Val Ser 
            820                 825                 830         


Thr Leu Gln Asn Gln Arg Ser Gln Arg Ser Trp Arg Leu Ala Cys Glu 
        835                 840                 845             


Ser Ala Ser Ser Thr Glu Val Ser Gly Ala Leu Lys Ser Thr Ser Cys 
    850                 855                 860                 


Ser Ile Asn His Pro Ile Phe Pro Glu Asn Ser Glu Val Thr Phe Asn 
865                 870                 875                 880 


Ile Thr Phe Asp Val Asp Ser Lys Ala Ser Leu Gly Asn Lys Leu Leu 
                885                 890                 895     


Leu Lys Ala Asn Val Thr Ser Glu Asn Asn Met Pro Arg Thr Asn Lys 
            900                 905                 910         


Thr Glu Phe Gln Leu Glu Leu Pro Val Lys Tyr Ala Val Tyr Met Val 
        915                 920                 925             


Val Thr Ser His Gly Val Ser Thr Lys Tyr Leu Asn Phe Thr Ala Ser 
    930                 935                 940                 


Glu Asn Thr Ser Arg Val Met Gln His Gln Tyr Gln Val Ser Asn Leu 
945                 950                 955                 960 


Gly Gln Arg Ser Leu Pro Ile Ser Leu Val Phe Leu Val Pro Val Arg 
                965                 970                 975     


Leu Asn Gln Thr Val Ile Trp Asp Arg Pro Gln Val Thr Phe Ser Glu 
            980                 985                 990         


Asn Leu Ser Ser Thr Cys His Thr  Lys Glu Arg Leu Pro  Ser His Ser 
        995                 1000                 1005             


Asp Phe  Leu Ala Glu Leu Arg  Lys Ala Pro Val Val  Asn Cys Ser 
    1010                 1015                 1020             


Ile Ala  Val Cys Gln Arg Ile  Gln Cys Asp Ile Pro  Phe Phe Gly 
    1025                 1030                 1035             


Ile Gln  Glu Glu Phe Asn Ala  Thr Leu Lys Gly Asn  Leu Ser Phe 
    1040                 1045                 1050             


Asp Trp  Tyr Ile Lys Thr Ser  His Asn His Leu Leu  Ile Val Ser 
    1055                 1060                 1065             


Thr Ala  Glu Ile Leu Phe Asn  Asp Ser Val Phe Thr  Leu Leu Pro 
    1070                 1075                 1080             


Gly Gln  Gly Ala Phe Val Arg  Ser Gln Thr Glu Thr  Lys Val Glu 
    1085                 1090                 1095             


Pro Phe  Glu Val Pro Asn Pro  Leu Pro Leu Ile Val  Gly Ser Ser 
    1100                 1105                 1110             


Val Gly  Gly Leu Leu Leu Leu  Ala Leu Ile Thr Ala  Ala Leu Tyr 
    1115                 1120                 1125             


Lys Leu  Gly Phe Phe Lys Arg  Gln Tyr Lys Asp Met  Met Ser Glu 
    1130                 1135                 1140             


Gly Gly  Pro Pro Gly Ala Glu  Pro Gln 
    1145                 1150         


<210>  78
<211>  467
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  78

Met Phe Ser Leu Lys Thr Leu Pro Phe Leu Leu Leu Leu His Val Gln 
1               5                   10                  15      


Ile Ser Lys Ala Phe Pro Val Ser Ser Lys Glu Lys Asn Thr Lys Thr 
            20                  25                  30          


Val Gln Asp Tyr Leu Glu Lys Phe Tyr Gln Leu Pro Ser Asn Gln Tyr 
        35                  40                  45              


Gln Ser Thr Arg Lys Asn Gly Thr Asn Val Ile Val Glu Lys Leu Lys 
    50                  55                  60                  


Glu Met Gln Arg Phe Phe Gly Leu Asn Val Thr Gly Lys Pro Asn Glu 
65                  70                  75                  80  


Glu Thr Leu Asp Met Met Lys Lys Pro Arg Cys Gly Val Pro Asp Ser 
                85                  90                  95      


Gly Gly Phe Met Leu Thr Pro Gly Asn Pro Lys Trp Glu Arg Thr Asn 
            100                 105                 110         


Leu Thr Tyr Arg Ile Arg Asn Tyr Thr Pro Gln Leu Ser Glu Ala Glu 
        115                 120                 125             


Val Glu Arg Ala Ile Lys Asp Ala Phe Glu Leu Trp Ser Val Ala Ser 
    130                 135                 140                 


Pro Leu Ile Phe Thr Arg Ile Ser Gln Gly Glu Ala Asp Ile Asn Ile 
145                 150                 155                 160 


Ala Phe Tyr Gln Arg Asp His Gly Asp Asn Ser Pro Phe Asp Gly Pro 
                165                 170                 175     


Asn Gly Ile Leu Ala His Ala Phe Gln Pro Gly Gln Gly Ile Gly Gly 
            180                 185                 190         


Asp Ala His Phe Asp Ala Glu Glu Thr Trp Thr Asn Thr Ser Ala Asn 
        195                 200                 205             


Tyr Asn Leu Phe Leu Val Ala Ala His Glu Phe Gly His Ser Leu Gly 
    210                 215                 220                 


Leu Ala His Ser Ser Asp Pro Gly Ala Leu Met Tyr Pro Asn Tyr Ala 
225                 230                 235                 240 


Phe Arg Glu Thr Ser Asn Tyr Ser Leu Pro Gln Asp Asp Ile Asp Gly 
                245                 250                 255     


Ile Gln Ala Ile Tyr Gly Leu Ser Ser Asn Pro Ile Gln Pro Thr Gly 
            260                 265                 270         


Pro Ser Thr Pro Lys Pro Cys Asp Pro Ser Leu Thr Phe Asp Ala Ile 
        275                 280                 285             


Thr Thr Leu Arg Gly Glu Ile Leu Phe Phe Lys Asp Arg Tyr Phe Trp 
    290                 295                 300                 


Arg Arg His Pro Gln Leu Gln Arg Val Glu Met Asn Phe Ile Ser Leu 
305                 310                 315                 320 


Phe Trp Pro Ser Leu Pro Thr Gly Ile Gln Ala Ala Tyr Glu Asp Phe 
                325                 330                 335     


Asp Arg Asp Leu Ile Phe Leu Phe Lys Gly Asn Gln Tyr Trp Ala Leu 
            340                 345                 350         


Ser Gly Tyr Asp Ile Leu Gln Gly Tyr Pro Lys Asp Ile Ser Asn Tyr 
        355                 360                 365             


Gly Phe Pro Ser Ser Val Gln Ala Ile Asp Ala Ala Val Phe Tyr Arg 
    370                 375                 380                 


Ser Lys Thr Tyr Phe Phe Val Asn Asp Gln Phe Trp Arg Tyr Asp Asn 
385                 390                 395                 400 


Gln Arg Gln Phe Met Glu Pro Gly Tyr Pro Lys Ser Ile Ser Gly Ala 
                405                 410                 415     


Phe Pro Gly Ile Glu Ser Lys Val Asp Ala Val Phe Gln Gln Glu His 
            420                 425                 430         


Phe Phe His Val Phe Ser Gly Pro Arg Tyr Tyr Ala Phe Asp Leu Ile 
        435                 440                 445             


Ala Gln Arg Val Thr Arg Val Ala Arg Gly Asn Lys Trp Leu Asn Cys 
    450                 455                 460                 


Arg Tyr Gly 
465         


<210>  79
<211>  707
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  79

Met Ser Leu Trp Gln Pro Leu Val Leu Val Leu Leu Val Leu Gly Cys 
1               5                   10                  15      


Cys Phe Ala Ala Pro Arg Gln Arg Gln Ser Thr Leu Val Leu Phe Pro 
            20                  25                  30          


Gly Asp Leu Arg Thr Asn Leu Thr Asp Arg Gln Leu Ala Glu Glu Tyr 
        35                  40                  45              


Leu Tyr Arg Tyr Gly Tyr Thr Arg Val Ala Glu Met Arg Gly Glu Ser 
    50                  55                  60                  


Lys Ser Leu Gly Pro Ala Leu Leu Leu Leu Gln Lys Gln Leu Ser Leu 
65                  70                  75                  80  


Pro Glu Thr Gly Glu Leu Asp Ser Ala Thr Leu Lys Ala Met Arg Thr 
                85                  90                  95      


Pro Arg Cys Gly Val Pro Asp Leu Gly Arg Phe Gln Thr Phe Glu Gly 
            100                 105                 110         


Asp Leu Lys Trp His His His Asn Ile Thr Tyr Trp Ile Gln Asn Tyr 
        115                 120                 125             


Ser Glu Asp Leu Pro Arg Ala Val Ile Asp Asp Ala Phe Ala Arg Ala 
    130                 135                 140                 


Phe Ala Leu Trp Ser Ala Val Thr Pro Leu Thr Phe Thr Arg Val Tyr 
145                 150                 155                 160 


Ser Arg Asp Ala Asp Ile Val Ile Gln Phe Gly Val Ala Glu His Gly 
                165                 170                 175     


Asp Gly Tyr Pro Phe Asp Gly Lys Asp Gly Leu Leu Ala His Ala Phe 
            180                 185                 190         


Pro Pro Gly Pro Gly Ile Gln Gly Asp Ala His Phe Asp Asp Asp Glu 
        195                 200                 205             


Leu Trp Ser Leu Gly Lys Gly Val Val Val Pro Thr Arg Phe Gly Asn 
    210                 215                 220                 


Ala Asp Gly Ala Ala Cys His Phe Pro Phe Ile Phe Glu Gly Arg Ser 
225                 230                 235                 240 


Tyr Ser Ala Cys Thr Thr Asp Gly Arg Ser Asp Gly Leu Pro Trp Cys 
                245                 250                 255     


Ser Thr Thr Ala Asn Tyr Asp Thr Asp Asp Arg Phe Gly Phe Cys Pro 
            260                 265                 270         


Ser Glu Arg Leu Tyr Thr Gln Asp Gly Asn Ala Asp Gly Lys Pro Cys 
        275                 280                 285             


Gln Phe Pro Phe Ile Phe Gln Gly Gln Ser Tyr Ser Ala Cys Thr Thr 
    290                 295                 300                 


Asp Gly Arg Ser Asp Gly Tyr Arg Trp Cys Ala Thr Thr Ala Asn Tyr 
305                 310                 315                 320 


Asp Arg Asp Lys Leu Phe Gly Phe Cys Pro Thr Arg Ala Asp Ser Thr 
                325                 330                 335     


Val Met Gly Gly Asn Ser Ala Gly Glu Leu Cys Val Phe Pro Phe Thr 
            340                 345                 350         


Phe Leu Gly Lys Glu Tyr Ser Thr Cys Thr Ser Glu Gly Arg Gly Asp 
        355                 360                 365             


Gly Arg Leu Trp Cys Ala Thr Thr Ser Asn Phe Asp Ser Asp Lys Lys 
    370                 375                 380                 


Trp Gly Phe Cys Pro Asp Gln Gly Tyr Ser Leu Phe Leu Val Ala Ala 
385                 390                 395                 400 


His Glu Phe Gly His Ala Leu Gly Leu Asp His Ser Ser Val Pro Glu 
                405                 410                 415     


Ala Leu Met Tyr Pro Met Tyr Arg Phe Thr Glu Gly Pro Pro Leu His 
            420                 425                 430         


Lys Asp Asp Val Asn Gly Ile Arg His Leu Tyr Gly Pro Arg Pro Glu 
        435                 440                 445             


Pro Glu Pro Arg Pro Pro Thr Thr Thr Thr Pro Gln Pro Thr Ala Pro 
    450                 455                 460                 


Pro Thr Val Cys Pro Thr Gly Pro Pro Thr Val His Pro Ser Glu Arg 
465                 470                 475                 480 


Pro Thr Ala Gly Pro Thr Gly Pro Pro Ser Ala Gly Pro Thr Gly Pro 
                485                 490                 495     


Pro Thr Ala Gly Pro Ser Thr Ala Thr Thr Val Pro Leu Ser Pro Val 
            500                 505                 510         


Asp Asp Ala Cys Asn Val Asn Ile Phe Asp Ala Ile Ala Glu Ile Gly 
        515                 520                 525             


Asn Gln Leu Tyr Leu Phe Lys Asp Gly Lys Tyr Trp Arg Phe Ser Glu 
    530                 535                 540                 


Gly Arg Gly Ser Arg Pro Gln Gly Pro Phe Leu Ile Ala Asp Lys Trp 
545                 550                 555                 560 


Pro Ala Leu Pro Arg Lys Leu Asp Ser Val Phe Glu Glu Arg Leu Ser 
                565                 570                 575     


Lys Lys Leu Phe Phe Phe Ser Gly Arg Gln Val Trp Val Tyr Thr Gly 
            580                 585                 590         


Ala Ser Val Leu Gly Pro Arg Arg Leu Asp Lys Leu Gly Leu Gly Ala 
        595                 600                 605             


Asp Val Ala Gln Val Thr Gly Ala Leu Arg Ser Gly Arg Gly Lys Met 
    610                 615                 620                 


Leu Leu Phe Ser Gly Arg Arg Leu Trp Arg Phe Asp Val Lys Ala Gln 
625                 630                 635                 640 


Met Val Asp Pro Arg Ser Ala Ser Glu Val Asp Arg Met Phe Pro Gly 
                645                 650                 655     


Val Pro Leu Asp Thr His Asp Val Phe Gln Tyr Arg Glu Lys Ala Tyr 
            660                 665                 670         


Phe Cys Gln Asp Arg Phe Tyr Trp Arg Val Ser Ser Arg Ser Glu Leu 
        675                 680                 685             


Asn Gln Val Asp Gln Val Gly Tyr Val Thr Tyr Asp Ile Leu Gln Cys 
    690                 695                 700                 


Pro Glu Asp 
705         


<210>  80
<211>  471
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  80

Met His Pro Gly Val Leu Ala Ala Phe Leu Phe Leu Ser Trp Thr His 
1               5                   10                  15      


Cys Arg Ala Leu Pro Leu Pro Ser Gly Gly Asp Glu Asp Asp Leu Ser 
            20                  25                  30          


Glu Glu Asp Leu Gln Phe Ala Glu Arg Tyr Leu Arg Ser Tyr Tyr His 
        35                  40                  45              


Pro Thr Asn Leu Ala Gly Ile Leu Lys Glu Asn Ala Ala Ser Ser Met 
    50                  55                  60                  


Thr Glu Arg Leu Arg Glu Met Gln Ser Phe Phe Gly Leu Glu Val Thr 
65                  70                  75                  80  


Gly Lys Leu Asp Asp Asn Thr Leu Asp Val Met Lys Lys Pro Arg Cys 
                85                  90                  95      


Gly Val Pro Asp Val Gly Glu Tyr Asn Val Phe Pro Arg Thr Leu Lys 
            100                 105                 110         


Trp Ser Lys Met Asn Leu Thr Tyr Arg Ile Val Asn Tyr Thr Pro Asp 
        115                 120                 125             


Met Thr His Ser Glu Val Glu Lys Ala Phe Lys Lys Ala Phe Lys Val 
    130                 135                 140                 


Trp Ser Asp Val Thr Pro Leu Asn Phe Thr Arg Leu His Asp Gly Ile 
145                 150                 155                 160 


Ala Asp Ile Met Ile Ser Phe Gly Ile Lys Glu His Gly Asp Phe Tyr 
                165                 170                 175     


Pro Phe Asp Gly Pro Ser Gly Leu Leu Ala His Ala Phe Pro Pro Gly 
            180                 185                 190         


Pro Asn Tyr Gly Gly Asp Ala His Phe Asp Asp Asp Glu Thr Trp Thr 
        195                 200                 205             


Ser Ser Ser Lys Gly Tyr Asn Leu Phe Leu Val Ala Ala His Glu Phe 
    210                 215                 220                 


Gly His Ser Leu Gly Leu Asp His Ser Lys Asp Pro Gly Ala Leu Met 
225                 230                 235                 240 


Phe Pro Ile Tyr Thr Tyr Thr Gly Lys Ser His Phe Met Leu Pro Asp 
                245                 250                 255     


Asp Asp Val Gln Gly Ile Gln Ser Leu Tyr Gly Pro Gly Asp Glu Asp 
            260                 265                 270         


Pro Asn Pro Lys His Pro Lys Thr Pro Asp Lys Cys Asp Pro Ser Leu 
        275                 280                 285             


Ser Leu Asp Ala Ile Thr Ser Leu Arg Gly Glu Thr Met Ile Phe Lys 
    290                 295                 300                 


Asp Arg Phe Phe Trp Arg Leu His Pro Gln Gln Val Asp Ala Glu Leu 
305                 310                 315                 320 


Phe Leu Thr Lys Ser Phe Trp Pro Glu Leu Pro Asn Arg Ile Asp Ala 
                325                 330                 335     


Ala Tyr Glu His Pro Ser His Asp Leu Ile Phe Ile Phe Arg Gly Arg 
            340                 345                 350         


Lys Phe Trp Ala Leu Asn Gly Tyr Asp Ile Leu Glu Gly Tyr Pro Lys 
        355                 360                 365             


Lys Ile Ser Glu Leu Gly Leu Pro Lys Glu Val Lys Lys Ile Ser Ala 
    370                 375                 380                 


Ala Val His Phe Glu Asp Thr Gly Lys Thr Leu Leu Phe Ser Gly Asn 
385                 390                 395                 400 


Gln Val Trp Arg Tyr Asp Asp Thr Asn His Ile Met Asp Lys Asp Tyr 
                405                 410                 415     


Pro Arg Leu Ile Glu Glu Asp Phe Pro Gly Ile Gly Asp Lys Val Asp 
            420                 425                 430         


Ala Val Tyr Glu Lys Asn Gly Tyr Ile Tyr Phe Phe Asn Gly Pro Ile 
        435                 440                 445             


Gln Phe Glu Tyr Ser Ile Trp Ser Asn Arg Ile Val Arg Val Met Pro 
    450                 455                 460                 


Ala Asn Ser Ile Leu Trp Cys 
465                 470     


<210>  81
<211>  355
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  81

Met Glu Thr Pro Asn Thr Thr Glu Asp Tyr Asp Thr Thr Thr Glu Phe 
1               5                   10                  15      


Asp Tyr Gly Asp Ala Thr Pro Cys Gln Lys Val Asn Glu Arg Ala Phe 
            20                  25                  30          


Gly Ala Gln Leu Leu Pro Pro Leu Tyr Ser Leu Val Phe Val Ile Gly 
        35                  40                  45              


Leu Val Gly Asn Ile Leu Val Val Leu Val Leu Val Gln Tyr Lys Arg 
    50                  55                  60                  


Leu Lys Asn Met Thr Ser Ile Tyr Leu Leu Asn Leu Ala Ile Ser Asp 
65                  70                  75                  80  


Leu Leu Phe Leu Phe Thr Leu Pro Phe Trp Ile Asp Tyr Lys Leu Lys 
                85                  90                  95      


Asp Asp Trp Val Phe Gly Asp Ala Met Cys Lys Ile Leu Ser Gly Phe 
            100                 105                 110         


Tyr Tyr Thr Gly Leu Tyr Ser Glu Ile Phe Phe Ile Ile Leu Leu Thr 
        115                 120                 125             


Ile Asp Arg Tyr Leu Ala Ile Val His Ala Val Phe Ala Leu Arg Ala 
    130                 135                 140                 


Arg Thr Val Thr Phe Gly Val Ile Thr Ser Ile Ile Ile Trp Ala Leu 
145                 150                 155                 160 


Ala Ile Leu Ala Ser Met Pro Gly Leu Tyr Phe Ser Lys Thr Gln Trp 
                165                 170                 175     


Glu Phe Thr His His Thr Cys Ser Leu His Phe Pro His Glu Ser Leu 
            180                 185                 190         


Arg Glu Trp Lys Leu Phe Gln Ala Leu Lys Leu Asn Leu Phe Gly Leu 
        195                 200                 205             


Val Leu Pro Leu Leu Val Met Ile Ile Cys Tyr Thr Gly Ile Ile Lys 
    210                 215                 220                 


Ile Leu Leu Arg Arg Pro Asn Glu Lys Lys Ser Lys Ala Val Arg Leu 
225                 230                 235                 240 


Ile Phe Val Ile Met Ile Ile Phe Phe Leu Phe Trp Thr Pro Tyr Asn 
                245                 250                 255     


Leu Thr Ile Leu Ile Ser Val Phe Gln Asp Phe Leu Phe Thr His Glu 
            260                 265                 270         


Cys Glu Gln Ser Arg His Leu Asp Leu Ala Val Gln Val Thr Glu Val 
        275                 280                 285             


Ile Ala Tyr Thr His Cys Cys Val Asn Pro Val Ile Tyr Ala Phe Val 
    290                 295                 300                 


Gly Glu Arg Phe Arg Lys Tyr Leu Arg Gln Leu Phe His Arg Arg Val 
305                 310                 315                 320 


Ala Val His Leu Val Lys Trp Leu Pro Phe Leu Ser Val Asp Arg Leu 
                325                 330                 335     


Glu Arg Val Ser Ser Thr Ser Pro Ser Thr Gly Glu His Glu Leu Ser 
            340                 345                 350         


Ala Gly Phe 
        355 


<210>  82
<211>  211
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  82

Met Arg Thr Leu Ala Cys Leu Leu Leu Leu Gly Cys Gly Tyr Leu Ala 
1               5                   10                  15      


His Val Leu Ala Glu Glu Ala Glu Ile Pro Arg Glu Val Ile Glu Arg 
            20                  25                  30          


Leu Ala Arg Ser Gln Ile His Ser Ile Arg Asp Leu Gln Arg Leu Leu 
        35                  40                  45              


Glu Ile Asp Ser Val Gly Ser Glu Asp Ser Leu Asp Thr Ser Leu Arg 
    50                  55                  60                  


Ala His Gly Val His Ala Thr Lys His Val Pro Glu Lys Arg Pro Leu 
65                  70                  75                  80  


Pro Ile Arg Arg Lys Arg Ser Ile Glu Glu Ala Val Pro Ala Val Cys 
                85                  90                  95      


Lys Thr Arg Thr Val Ile Tyr Glu Ile Pro Arg Ser Gln Val Asp Pro 
            100                 105                 110         


Thr Ser Ala Asn Phe Leu Ile Trp Pro Pro Cys Val Glu Val Lys Arg 
        115                 120                 125             


Cys Thr Gly Cys Cys Asn Thr Ser Ser Val Lys Cys Gln Pro Ser Arg 
    130                 135                 140                 


Val His His Arg Ser Val Lys Val Ala Lys Val Glu Tyr Val Arg Lys 
145                 150                 155                 160 


Lys Pro Lys Leu Lys Glu Val Gln Val Arg Leu Glu Glu His Leu Glu 
                165                 170                 175     


Cys Ala Cys Ala Thr Thr Ser Leu Asn Pro Asp Tyr Arg Glu Glu Asp 
            180                 185                 190         


Thr Gly Arg Pro Arg Glu Ser Gly Lys Lys Arg Lys Arg Lys Arg Leu 
        195                 200                 205             


Lys Pro Thr 
    210     


<210>  83
<211>  241
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  83

Met Asn Arg Cys Trp Ala Leu Phe Leu Ser Leu Cys Cys Tyr Leu Arg 
1               5                   10                  15      


Leu Val Ser Ala Glu Gly Asp Pro Ile Pro Glu Glu Leu Tyr Glu Met 
            20                  25                  30          


Leu Ser Asp His Ser Ile Arg Ser Phe Asp Asp Leu Gln Arg Leu Leu 
        35                  40                  45              


His Gly Asp Pro Gly Glu Glu Asp Gly Ala Glu Leu Asp Leu Asn Met 
    50                  55                  60                  


Thr Arg Ser His Ser Gly Gly Glu Leu Glu Ser Leu Ala Arg Gly Arg 
65                  70                  75                  80  


Arg Ser Leu Gly Ser Leu Thr Ile Ala Glu Pro Ala Met Ile Ala Glu 
                85                  90                  95      


Cys Lys Thr Arg Thr Glu Val Phe Glu Ile Ser Arg Arg Leu Ile Asp 
            100                 105                 110         


Arg Thr Asn Ala Asn Phe Leu Val Trp Pro Pro Cys Val Glu Val Gln 
        115                 120                 125             


Arg Cys Ser Gly Cys Cys Asn Asn Arg Asn Val Gln Cys Arg Pro Thr 
    130                 135                 140                 


Gln Val Gln Leu Arg Pro Val Gln Val Arg Lys Ile Glu Ile Val Arg 
145                 150                 155                 160 


Lys Lys Pro Ile Phe Lys Lys Ala Thr Val Thr Leu Glu Asp His Leu 
                165                 170                 175     


Ala Cys Lys Cys Glu Thr Val Ala Ala Ala Arg Pro Val Thr Arg Ser 
            180                 185                 190         


Pro Gly Gly Ser Gln Glu Gln Arg Ala Lys Thr Pro Gln Thr Arg Val 
        195                 200                 205             


Thr Ile Arg Thr Val Arg Val Arg Arg Pro Pro Lys Gly Lys His Arg 
    210                 215                 220                 


Lys Phe Lys His Thr His Asp Lys Thr Ala Leu Lys Glu Thr Leu Gly 
225                 230                 235                 240 


Ala 
    


<210>  84
<211>  345
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  84

Met Ser Leu Phe Gly Leu Leu Leu Leu Thr Ser Ala Leu Ala Gly Gln 
1               5                   10                  15      


Arg Gln Gly Thr Gln Ala Glu Ser Asn Leu Ser Ser Lys Phe Gln Phe 
            20                  25                  30          


Ser Ser Asn Lys Glu Gln Asn Gly Val Gln Asp Pro Gln His Glu Arg 
        35                  40                  45              


Ile Ile Thr Val Ser Thr Asn Gly Ser Ile His Ser Pro Arg Phe Pro 
    50                  55                  60                  


His Thr Tyr Pro Arg Asn Thr Val Leu Val Trp Arg Leu Val Ala Val 
65                  70                  75                  80  


Glu Glu Asn Val Trp Ile Gln Leu Thr Phe Asp Glu Arg Phe Gly Leu 
                85                  90                  95      


Glu Asp Pro Glu Asp Asp Ile Cys Lys Tyr Asp Phe Val Glu Val Glu 
            100                 105                 110         


Glu Pro Ser Asp Gly Thr Ile Leu Gly Arg Trp Cys Gly Ser Gly Thr 
        115                 120                 125             


Val Pro Gly Lys Gln Ile Ser Lys Gly Asn Gln Ile Arg Ile Arg Phe 
    130                 135                 140                 


Val Ser Asp Glu Tyr Phe Pro Ser Glu Pro Gly Phe Cys Ile His Tyr 
145                 150                 155                 160 


Asn Ile Val Met Pro Gln Phe Thr Glu Ala Val Ser Pro Ser Val Leu 
                165                 170                 175     


Pro Pro Ser Ala Leu Pro Leu Asp Leu Leu Asn Asn Ala Ile Thr Ala 
            180                 185                 190         


Phe Ser Thr Leu Glu Asp Leu Ile Arg Tyr Leu Glu Pro Glu Arg Trp 
        195                 200                 205             


Gln Leu Asp Leu Glu Asp Leu Tyr Arg Pro Thr Trp Gln Leu Leu Gly 
    210                 215                 220                 


Lys Ala Phe Val Phe Gly Arg Lys Ser Arg Val Val Asp Leu Asn Leu 
225                 230                 235                 240 


Leu Thr Glu Glu Val Arg Leu Tyr Ser Cys Thr Pro Arg Asn Phe Ser 
                245                 250                 255     


Val Ser Ile Arg Glu Glu Leu Lys Arg Thr Asp Thr Ile Phe Trp Pro 
            260                 265                 270         


Gly Cys Leu Leu Val Lys Arg Cys Gly Gly Asn Cys Ala Cys Cys Leu 
        275                 280                 285             


His Asn Cys Asn Glu Cys Gln Cys Val Pro Ser Lys Val Thr Lys Lys 
    290                 295                 300                 


Tyr His Glu Val Leu Gln Leu Arg Pro Lys Thr Gly Val Arg Gly Leu 
305                 310                 315                 320 


His Lys Ser Leu Thr Asp Val Ala Leu Glu His His Glu Glu Cys Asp 
                325                 330                 335     


Cys Val Cys Arg Gly Ser Thr Gly Gly 
            340                 345 


<210>  85
<211>  364
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  85

Met His Arg Leu Ile Phe Val Tyr Thr Leu Ile Cys Ala Asn Phe Cys 
1               5                   10                  15      


Ser Cys Arg Asp Thr Ser Ala Thr Pro Gln Ser Ala Ser Ile Lys Ala 
            20                  25                  30          


Leu Arg Asn Ala Asn Leu Arg Arg Asp Asp Leu Tyr Arg Arg Asp Glu 
        35                  40                  45              


Thr Ile Gln Val Lys Gly Asn Gly Tyr Val Gln Ser Pro Arg Phe Pro 
    50                  55                  60                  


Asn Ser Tyr Pro Arg Asn Leu Leu Leu Thr Trp Arg Leu His Ser Gln 
65                  70                  75                  80  


Glu Asn Thr Arg Ile Gln Leu Val Phe Asp Asn Gln Phe Gly Leu Glu 
                85                  90                  95      


Glu Ala Glu Asn Asp Ile Cys Arg Tyr Asp Phe Val Glu Val Glu Asp 
            100                 105                 110         


Ile Ser Glu Thr Ser Thr Ile Ile Arg Gly Arg Trp Cys Gly His Lys 
        115                 120                 125             


Glu Val Pro Pro Arg Ile Lys Ser Arg Thr Asn Gln Ile Lys Ile Thr 
    130                 135                 140                 


Phe Lys Ser Asp Asp Tyr Phe Val Ala Lys Pro Gly Phe Lys Ile Tyr 
145                 150                 155                 160 


Tyr Ser Leu Leu Glu Asp Phe Gln Pro Ala Ala Ala Ser Glu Thr Asn 
                165                 170                 175     


Trp Glu Ser Val Thr Ser Ser Ile Ser Gly Val Ser Tyr Asn Ser Pro 
            180                 185                 190         


Ser Val Thr Asp Pro Thr Leu Ile Ala Asp Ala Leu Asp Lys Lys Ile 
        195                 200                 205             


Ala Glu Phe Asp Thr Val Glu Asp Leu Leu Lys Tyr Phe Asn Pro Glu 
    210                 215                 220                 


Ser Trp Gln Glu Asp Leu Glu Asn Met Tyr Leu Asp Thr Pro Arg Tyr 
225                 230                 235                 240 


Arg Gly Arg Ser Tyr His Asp Arg Lys Ser Lys Val Asp Leu Asp Arg 
                245                 250                 255     


Leu Asn Asp Asp Ala Lys Arg Tyr Ser Cys Thr Pro Arg Asn Tyr Ser 
            260                 265                 270         


Val Asn Ile Arg Glu Glu Leu Lys Leu Ala Asn Val Val Phe Phe Pro 
        275                 280                 285             


Arg Cys Leu Leu Val Gln Arg Cys Gly Gly Asn Cys Gly Cys Gly Thr 
    290                 295                 300                 


Val Asn Trp Arg Ser Cys Thr Cys Asn Ser Gly Lys Thr Val Lys Lys 
305                 310                 315                 320 


Tyr His Glu Val Leu Gln Phe Glu Pro Gly His Ile Lys Arg Arg Gly 
                325                 330                 335     


Arg Ala Lys Thr Met Ala Leu Val Asp Ile Gln Leu Asp His His Glu 
            340                 345                 350         


Arg Cys Asp Cys Ile Cys Ser Ser Arg Pro Pro Arg 
        355                 360                 


<210>  86
<211>  225
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  86

Met Val Thr His Ser Lys Phe Pro Ala Ala Gly Met Ser Arg Pro Leu 
1               5                   10                  15      


Asp Thr Ser Leu Arg Leu Lys Thr Phe Ser Ser Lys Ser Glu Tyr Gln 
            20                  25                  30          


Leu Val Val Asn Ala Val Arg Lys Leu Gln Glu Ser Gly Phe Tyr Trp 
        35                  40                  45              


Ser Ala Val Thr Gly Gly Glu Ala Asn Leu Leu Leu Ser Ala Glu Pro 
    50                  55                  60                  


Ala Gly Thr Phe Leu Ile Arg Asp Ser Ser Asp Gln Arg His Phe Phe 
65                  70                  75                  80  


Thr Leu Ser Val Lys Thr Gln Ser Gly Thr Lys Asn Leu Arg Ile Gln 
                85                  90                  95      


Cys Glu Gly Gly Ser Phe Ser Leu Gln Ser Asp Pro Arg Ser Thr Gln 
            100                 105                 110         


Pro Val Pro Arg Phe Asp Cys Val Leu Lys Leu Val His His Tyr Met 
        115                 120                 125             


Pro Pro Pro Gly Ala Pro Ser Phe Pro Ser Pro Pro Thr Glu Pro Ser 
    130                 135                 140                 


Ser Glu Val Pro Glu Gln Pro Ser Ala Gln Pro Leu Pro Gly Ser Pro 
145                 150                 155                 160 


Pro Arg Arg Ala Tyr Tyr Ile Tyr Ser Gly Gly Glu Lys Ile Pro Leu 
                165                 170                 175     


Val Leu Ser Arg Pro Leu Ser Ser Asn Val Ala Thr Leu Gln His Leu 
            180                 185                 190         


Cys Arg Lys Thr Val Asn Gly His Leu Asp Ser Tyr Glu Lys Val Thr 
        195                 200                 205             


Gln Leu Pro Gly Pro Ile Arg Glu Phe Leu Asp Gln Tyr Asp Ala Pro 
    210                 215                 220                 


Leu 
225 


<210>  87
<211>  160
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  87

Met Val Pro Ser Ala Gly Gln Leu Ala Leu Phe Ala Leu Gly Ile Val 
1               5                   10                  15      


Leu Ala Ala Cys Gln Ala Leu Glu Asn Ser Thr Ser Pro Leu Ser Ala 
            20                  25                  30          


Asp Pro Pro Val Ala Ala Ala Val Val Ser His Phe Asn Asp Cys Pro 
        35                  40                  45              


Asp Ser His Thr Gln Phe Cys Phe His Gly Thr Cys Arg Phe Leu Val 
    50                  55                  60                  


Gln Glu Asp Lys Pro Ala Cys Val Cys His Ser Gly Tyr Val Gly Ala 
65                  70                  75                  80  


Arg Cys Glu His Ala Asp Leu Leu Ala Val Val Ala Ala Ser Gln Lys 
                85                  90                  95      


Lys Gln Ala Ile Thr Ala Leu Val Val Val Ser Ile Val Ala Leu Ala 
            100                 105                 110         


Val Leu Ile Ile Thr Cys Val Leu Ile His Cys Cys Gln Val Arg Lys 
        115                 120                 125             


His Cys Glu Trp Cys Arg Ala Leu Ile Cys Arg His Glu Lys Pro Ser 
    130                 135                 140                 


Ala Leu Leu Lys Gly Arg Thr Ala Cys Cys His Ser Glu Thr Val Val 
145                 150                 155                 160 


<210>  88
<211>  390
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  88

Met Pro Pro Ser Gly Leu Arg Leu Leu Pro Leu Leu Leu Pro Leu Leu 
1               5                   10                  15      


Trp Leu Leu Val Leu Thr Pro Gly Arg Pro Ala Ala Gly Leu Ser Thr 
            20                  25                  30          


Cys Lys Thr Ile Asp Met Glu Leu Val Lys Arg Lys Arg Ile Glu Ala 
        35                  40                  45              


Ile Arg Gly Gln Ile Leu Ser Lys Leu Arg Leu Ala Ser Pro Pro Ser 
    50                  55                  60                  


Gln Gly Glu Val Pro Pro Gly Pro Leu Pro Glu Ala Val Leu Ala Leu 
65                  70                  75                  80  


Tyr Asn Ser Thr Arg Asp Arg Val Ala Gly Glu Ser Ala Glu Pro Glu 
                85                  90                  95      


Pro Glu Pro Glu Ala Asp Tyr Tyr Ala Lys Glu Val Thr Arg Val Leu 
            100                 105                 110         


Met Val Glu Thr His Asn Glu Ile Tyr Asp Lys Phe Lys Gln Ser Thr 
        115                 120                 125             


His Ser Ile Tyr Met Phe Phe Asn Thr Ser Glu Leu Arg Glu Ala Val 
    130                 135                 140                 


Pro Glu Pro Val Leu Leu Ser Arg Ala Glu Leu Arg Leu Leu Arg Leu 
145                 150                 155                 160 


Lys Leu Lys Val Glu Gln His Val Glu Leu Tyr Gln Lys Tyr Ser Asn 
                165                 170                 175     


Asn Ser Trp Arg Tyr Leu Ser Asn Arg Leu Leu Ala Pro Ser Asp Ser 
            180                 185                 190         


Pro Glu Trp Leu Ser Phe Asp Val Thr Gly Val Val Arg Gln Trp Leu 
        195                 200                 205             


Ser Arg Gly Gly Glu Ile Glu Gly Phe Arg Leu Ser Ala His Cys Ser 
    210                 215                 220                 


Cys Asp Ser Arg Asp Asn Thr Leu Gln Val Asp Ile Asn Gly Phe Thr 
225                 230                 235                 240 


Thr Gly Arg Arg Gly Asp Leu Ala Thr Ile His Gly Met Asn Arg Pro 
                245                 250                 255     


Phe Leu Leu Leu Met Ala Thr Pro Leu Glu Arg Ala Gln His Leu Gln 
            260                 265                 270         


Ser Ser Arg His Arg Arg Ala Leu Asp Thr Asn Tyr Cys Phe Ser Ser 
        275                 280                 285             


Thr Glu Lys Asn Cys Cys Val Arg Gln Leu Tyr Ile Asp Phe Arg Lys 
    290                 295                 300                 


Asp Leu Gly Trp Lys Trp Ile His Glu Pro Lys Gly Tyr His Ala Asn 
305                 310                 315                 320 


Phe Cys Leu Gly Pro Cys Pro Tyr Ile Trp Ser Leu Asp Thr Gln Tyr 
                325                 330                 335     


Ser Lys Val Leu Ala Leu Tyr Asn Gln His Asn Pro Gly Ala Ser Ala 
            340                 345                 350         


Ala Pro Cys Cys Val Pro Gln Ala Leu Glu Pro Leu Pro Ile Val Tyr 
        355                 360                 365             


Tyr Val Gly Arg Lys Pro Lys Val Glu Gln Leu Ser Asn Met Ile Val 
    370                 375                 380                 


Arg Ser Cys Lys Cys Ser 
385                 390 


<210>  89
<211>  414
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  89

Met His Tyr Cys Val Leu Ser Ala Phe Leu Ile Leu His Leu Val Thr 
1               5                   10                  15      


Val Ala Leu Ser Leu Ser Thr Cys Ser Thr Leu Asp Met Asp Gln Phe 
            20                  25                  30          


Met Arg Lys Arg Ile Glu Ala Ile Arg Gly Gln Ile Leu Ser Lys Leu 
        35                  40                  45              


Lys Leu Thr Ser Pro Pro Glu Asp Tyr Pro Glu Pro Glu Glu Val Pro 
    50                  55                  60                  


Pro Glu Val Ile Ser Ile Tyr Asn Ser Thr Arg Asp Leu Leu Gln Glu 
65                  70                  75                  80  


Lys Ala Ser Arg Arg Ala Ala Ala Cys Glu Arg Glu Arg Ser Asp Glu 
                85                  90                  95      


Glu Tyr Tyr Ala Lys Glu Val Tyr Lys Ile Asp Met Pro Pro Phe Phe 
            100                 105                 110         


Pro Ser Glu Asn Ala Ile Pro Pro Thr Phe Tyr Arg Pro Tyr Phe Arg 
        115                 120                 125             


Ile Val Arg Phe Asp Val Ser Ala Met Glu Lys Asn Ala Ser Asn Leu 
    130                 135                 140                 


Val Lys Ala Glu Phe Arg Val Phe Arg Leu Gln Asn Pro Lys Ala Arg 
145                 150                 155                 160 


Val Pro Glu Gln Arg Ile Glu Leu Tyr Gln Ile Leu Lys Ser Lys Asp 
                165                 170                 175     


Leu Thr Ser Pro Thr Gln Arg Tyr Ile Asp Ser Lys Val Val Lys Thr 
            180                 185                 190         


Arg Ala Glu Gly Glu Trp Leu Ser Phe Asp Val Thr Asp Ala Val His 
        195                 200                 205             


Glu Trp Leu His His Lys Asp Arg Asn Leu Gly Phe Lys Ile Ser Leu 
    210                 215                 220                 


His Cys Pro Cys Cys Thr Phe Val Pro Ser Asn Asn Tyr Ile Ile Pro 
225                 230                 235                 240 


Asn Lys Ser Glu Glu Leu Glu Ala Arg Phe Ala Gly Ile Asp Gly Thr 
                245                 250                 255     


Ser Thr Tyr Thr Ser Gly Asp Gln Lys Thr Ile Lys Ser Thr Arg Lys 
            260                 265                 270         


Lys Asn Ser Gly Lys Thr Pro His Leu Leu Leu Met Leu Leu Pro Ser 
        275                 280                 285             


Tyr Arg Leu Glu Ser Gln Gln Thr Asn Arg Arg Lys Lys Arg Ala Leu 
    290                 295                 300                 


Asp Ala Ala Tyr Cys Phe Arg Asn Val Gln Asp Asn Cys Cys Leu Arg 
305                 310                 315                 320 


Pro Leu Tyr Ile Asp Phe Lys Arg Asp Leu Gly Trp Lys Trp Ile His 
                325                 330                 335     


Glu Pro Lys Gly Tyr Asn Ala Asn Phe Cys Ala Gly Ala Cys Pro Tyr 
            340                 345                 350         


Leu Trp Ser Ser Asp Thr Gln His Ser Arg Val Leu Ser Leu Tyr Asn 
        355                 360                 365             


Thr Ile Asn Pro Glu Ala Ser Ala Ser Pro Cys Cys Val Ser Gln Asp 
    370                 375                 380                 


Leu Glu Pro Leu Thr Ile Leu Tyr Tyr Ile Gly Lys Thr Pro Lys Ile 
385                 390                 395                 400 


Glu Gln Leu Ser Asn Met Ile Val Lys Ser Cys Lys Cys Ser 
                405                 410                 


<210>  90
<211>  412
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  90

Met Lys Met His Leu Gln Arg Ala Leu Val Val Leu Ala Leu Leu Asn 
1               5                   10                  15      


Phe Ala Thr Val Ser Leu Ser Leu Ser Thr Cys Thr Thr Leu Asp Phe 
            20                  25                  30          


Gly His Ile Lys Lys Lys Arg Val Glu Ala Ile Arg Gly Gln Ile Leu 
        35                  40                  45              


Ser Lys Leu Arg Leu Thr Ser Pro Pro Glu Pro Thr Val Met Thr His 
    50                  55                  60                  


Val Pro Tyr Gln Val Leu Ala Leu Tyr Asn Ser Thr Arg Glu Leu Leu 
65                  70                  75                  80  


Glu Glu Met His Gly Glu Arg Glu Glu Gly Cys Thr Gln Glu Asn Thr 
                85                  90                  95      


Glu Ser Glu Tyr Tyr Ala Lys Glu Ile His Lys Phe Asp Met Ile Gln 
            100                 105                 110         


Gly Leu Ala Glu His Asn Glu Leu Ala Val Cys Pro Lys Gly Ile Thr 
        115                 120                 125             


Ser Lys Val Phe Arg Phe Asn Val Ser Ser Val Glu Lys Asn Arg Thr 
    130                 135                 140                 


Asn Leu Phe Arg Ala Glu Phe Arg Val Leu Arg Val Pro Asn Pro Ser 
145                 150                 155                 160 


Ser Lys Arg Asn Glu Gln Arg Ile Glu Leu Phe Gln Ile Leu Arg Pro 
                165                 170                 175     


Asp Glu His Ile Ala Lys Gln Arg Tyr Ile Gly Gly Lys Asn Leu Pro 
            180                 185                 190         


Thr Arg Gly Thr Ala Glu Trp Leu Ser Phe Asp Val Thr Asp Thr Val 
        195                 200                 205             


Arg Glu Trp Leu Leu Arg Arg Glu Ser Asn Leu Gly Leu Glu Ile Ser 
    210                 215                 220                 


Ile His Cys Pro Cys His Thr Phe Gln Pro Asn Gly Asp Ile Leu Glu 
225                 230                 235                 240 


Asn Ile His Glu Val Met Glu Ile Lys Phe Lys Gly Val Asp Asn Glu 
                245                 250                 255     


Asp Asp His Gly Arg Gly Asp Leu Gly Arg Leu Lys Lys Gln Lys Asp 
            260                 265                 270         


His His Asn Pro His Leu Ile Leu Met Met Ile Pro Pro His Arg Leu 
        275                 280                 285             


Asp Asn Pro Gly Gln Gly Gly Gln Arg Lys Lys Arg Ala Leu Asp Thr 
    290                 295                 300                 


Asn Tyr Cys Phe Arg Asn Leu Glu Glu Asn Cys Cys Val Arg Pro Leu 
305                 310                 315                 320 


Tyr Ile Asp Phe Arg Gln Asp Leu Gly Trp Lys Trp Val His Glu Pro 
                325                 330                 335     


Lys Gly Tyr Tyr Ala Asn Phe Cys Ser Gly Pro Cys Pro Tyr Leu Arg 
            340                 345                 350         


Ser Ala Asp Thr Thr His Ser Thr Val Leu Gly Leu Tyr Asn Thr Leu 
        355                 360                 365             


Asn Pro Glu Ala Ser Ala Ser Pro Cys Cys Val Pro Gln Asp Leu Glu 
    370                 375                 380                 


Pro Leu Thr Ile Leu Tyr Tyr Val Gly Arg Thr Pro Lys Val Glu Gln 
385                 390                 395                 400 


Leu Ser Asn Met Val Val Lys Ser Cys Lys Cys Ser 
                405                 410         


<210>  91
<211>  461
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  91

Met Ala Pro Val Ala Val Trp Ala Ala Leu Ala Val Gly Leu Glu Leu 
1               5                   10                  15      


Trp Ala Ala Ala His Ala Leu Pro Ala Gln Val Ala Phe Thr Pro Tyr 
            20                  25                  30          


Ala Pro Glu Pro Gly Ser Thr Cys Arg Leu Arg Glu Tyr Tyr Asp Gln 
        35                  40                  45              


Thr Ala Gln Met Cys Cys Ser Lys Cys Ser Pro Gly Gln His Ala Lys 
    50                  55                  60                  


Val Phe Cys Thr Lys Thr Ser Asp Thr Val Cys Asp Ser Cys Glu Asp 
65                  70                  75                  80  


Ser Thr Tyr Thr Gln Leu Trp Asn Trp Val Pro Glu Cys Leu Ser Cys 
                85                  90                  95      


Gly Ser Arg Cys Ser Ser Asp Gln Val Glu Thr Gln Ala Cys Thr Arg 
            100                 105                 110         


Glu Gln Asn Arg Ile Cys Thr Cys Arg Pro Gly Trp Tyr Cys Ala Leu 
        115                 120                 125             


Ser Lys Gln Glu Gly Cys Arg Leu Cys Ala Pro Leu Arg Lys Cys Arg 
    130                 135                 140                 


Pro Gly Phe Gly Val Ala Arg Pro Gly Thr Glu Thr Ser Asp Val Val 
145                 150                 155                 160 


Cys Lys Pro Cys Ala Pro Gly Thr Phe Ser Asn Thr Thr Ser Ser Thr 
                165                 170                 175     


Asp Ile Cys Arg Pro His Gln Ile Cys Asn Val Val Ala Ile Pro Gly 
            180                 185                 190         


Asn Ala Ser Met Asp Ala Val Cys Thr Ser Thr Ser Pro Thr Arg Ser 
        195                 200                 205             


Met Ala Pro Gly Ala Val His Leu Pro Gln Pro Val Ser Thr Arg Ser 
    210                 215                 220                 


Gln His Thr Gln Pro Thr Pro Glu Pro Ser Thr Ala Pro Ser Thr Ser 
225                 230                 235                 240 


Phe Leu Leu Pro Met Gly Pro Ser Pro Pro Ala Glu Gly Ser Thr Gly 
                245                 250                 255     


Asp Phe Ala Leu Pro Val Gly Leu Ile Val Gly Val Thr Ala Leu Gly 
            260                 265                 270         


Leu Leu Ile Ile Gly Val Val Asn Cys Val Ile Met Thr Gln Val Lys 
        275                 280                 285             


Lys Lys Pro Leu Cys Leu Gln Arg Glu Ala Lys Val Pro His Leu Pro 
    290                 295                 300                 


Ala Asp Lys Ala Arg Gly Thr Gln Gly Pro Glu Gln Gln His Leu Leu 
305                 310                 315                 320 


Ile Thr Ala Pro Ser Ser Ser Ser Ser Ser Leu Glu Ser Ser Ala Ser 
                325                 330                 335     


Ala Leu Asp Arg Arg Ala Pro Thr Arg Asn Gln Pro Gln Ala Pro Gly 
            340                 345                 350         


Val Glu Ala Ser Gly Ala Gly Glu Ala Arg Ala Ser Thr Gly Ser Ser 
        355                 360                 365             


Asp Ser Ser Pro Gly Gly His Gly Thr Gln Val Asn Val Thr Cys Ile 
    370                 375                 380                 


Val Asn Val Cys Ser Ser Ser Asp His Ser Ser Gln Cys Ser Ser Gln 
385                 390                 395                 400 


Ala Ser Ser Thr Met Gly Asp Thr Asp Ser Ser Pro Ser Glu Ser Pro 
                405                 410                 415     


Lys Asp Glu Gln Val Pro Phe Ser Lys Glu Glu Cys Ala Phe Arg Ser 
            420                 425                 430         


Gln Leu Glu Thr Pro Glu Thr Leu Leu Gly Ser Thr Glu Glu Lys Pro 
        435                 440                 445             


Leu Pro Leu Gly Val Pro Asp Ala Gly Met Lys Pro Ser 
    450                 455                 460     


<210>  92
<211>  170
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  92

Met Pro Val Met Arg Leu Phe Pro Cys Phe Leu Gln Leu Leu Ala Gly 
1               5                   10                  15      


Leu Ala Leu Pro Ala Val Pro Pro Gln Gln Trp Ala Leu Ser Ala Gly 
            20                  25                  30          


Asn Gly Ser Ser Glu Val Glu Val Val Pro Phe Gln Glu Val Trp Gly 
        35                  40                  45              


Arg Ser Tyr Cys Arg Ala Leu Glu Arg Leu Val Asp Val Val Ser Glu 
    50                  55                  60                  


Tyr Pro Ser Glu Val Glu His Met Phe Ser Pro Ser Cys Val Ser Leu 
65                  70                  75                  80  


Leu Arg Cys Thr Gly Cys Cys Gly Asp Glu Asn Leu His Cys Val Pro 
                85                  90                  95      


Val Glu Thr Ala Asn Val Thr Met Gln Leu Leu Lys Ile Arg Ser Gly 
            100                 105                 110         


Asp Arg Pro Ser Tyr Val Glu Leu Thr Phe Ser Gln His Val Arg Cys 
        115                 120                 125             


Glu Cys Arg Pro Leu Arg Glu Lys Met Lys Pro Glu Arg Arg Arg Pro 
    130                 135                 140                 


Lys Gly Arg Gly Lys Arg Arg Arg Glu Lys Gln Arg Pro Thr Asp Cys 
145                 150                 155                 160 


His Leu Cys Gly Asp Ala Val Pro Arg Arg 
                165                 170 


<210>  93
<211>  412
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  93

Met Thr Asp Arg Gln Thr Asp Thr Ala Pro Ser Pro Ser Tyr His Leu 
1               5                   10                  15      


Leu Pro Gly Arg Arg Arg Thr Val Asp Ala Ala Ala Ser Arg Gly Gln 
            20                  25                  30          


Gly Pro Glu Pro Ala Pro Gly Gly Gly Val Glu Gly Val Gly Ala Arg 
        35                  40                  45              


Gly Val Ala Leu Lys Leu Phe Val Gln Leu Leu Gly Cys Ser Arg Phe 
    50                  55                  60                  


Gly Gly Ala Val Val Arg Ala Gly Glu Ala Glu Pro Ser Gly Ala Ala 
65                  70                  75                  80  


Arg Ser Ala Ser Ser Gly Arg Glu Glu Pro Gln Pro Glu Glu Gly Glu 
                85                  90                  95      


Glu Glu Glu Glu Lys Glu Glu Glu Arg Gly Pro Gln Trp Arg Leu Gly 
            100                 105                 110         


Ala Arg Lys Pro Gly Ser Trp Thr Gly Glu Ala Ala Val Cys Ala Asp 
        115                 120                 125             


Ser Ala Pro Ala Ala Arg Ala Pro Gln Ala Leu Ala Arg Ala Ser Gly 
    130                 135                 140                 


Arg Gly Gly Arg Val Ala Arg Arg Gly Ala Glu Glu Ser Gly Pro Pro 
145                 150                 155                 160 


His Ser Pro Ser Arg Arg Gly Ser Ala Ser Arg Ala Gly Pro Gly Arg 
                165                 170                 175     


Ala Ser Glu Thr Met Asn Phe Leu Leu Ser Trp Val His Trp Ser Leu 
            180                 185                 190         


Ala Leu Leu Leu Tyr Leu His His Ala Lys Trp Ser Gln Ala Ala Pro 
        195                 200                 205             


Met Ala Glu Gly Gly Gly Gln Asn His His Glu Val Val Lys Phe Met 
    210                 215                 220                 


Asp Val Tyr Gln Arg Ser Tyr Cys His Pro Ile Glu Thr Leu Val Asp 
225                 230                 235                 240 


Ile Phe Gln Glu Tyr Pro Asp Glu Ile Glu Tyr Ile Phe Lys Pro Ser 
                245                 250                 255     


Cys Val Pro Leu Met Arg Cys Gly Gly Cys Cys Asn Asp Glu Gly Leu 
            260                 265                 270         


Glu Cys Val Pro Thr Glu Glu Ser Asn Ile Thr Met Gln Ile Met Arg 
        275                 280                 285             


Ile Lys Pro His Gln Gly Gln His Ile Gly Glu Met Ser Phe Leu Gln 
    290                 295                 300                 


His Asn Lys Cys Glu Cys Arg Pro Lys Lys Asp Arg Ala Arg Gln Glu 
305                 310                 315                 320 


Lys Lys Ser Val Arg Gly Lys Gly Lys Gly Gln Lys Arg Lys Arg Lys 
                325                 330                 335     


Lys Ser Arg Tyr Lys Ser Trp Ser Val Tyr Val Gly Ala Arg Cys Cys 
            340                 345                 350         


Leu Met Pro Trp Ser Leu Pro Gly Pro His Pro Cys Gly Pro Cys Ser 
        355                 360                 365             


Glu Arg Arg Lys His Leu Phe Val Gln Asp Pro Gln Thr Cys Lys Cys 
    370                 375                 380                 


Ser Cys Lys Asn Thr Asp Ser Arg Cys Lys Ala Arg Gln Leu Glu Leu 
385                 390                 395                 400 


Asn Glu Arg Thr Cys Arg Cys Asp Lys Pro Arg Arg 
                405                 410         


<210>  94
<211>  232
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  94

Met Asn Phe Leu Leu Ser Trp Val His Trp Ser Leu Ala Leu Leu Leu 
1               5                   10                  15      


Tyr Leu His His Ala Lys Trp Ser Gln Ala Ala Pro Met Ala Glu Gly 
            20                  25                  30          


Gly Gly Gln Asn His His Glu Val Val Lys Phe Met Asp Val Tyr Gln 
        35                  40                  45              


Arg Ser Tyr Cys His Pro Ile Glu Thr Leu Val Asp Ile Phe Gln Glu 
    50                  55                  60                  


Tyr Pro Asp Glu Ile Glu Tyr Ile Phe Lys Pro Ser Cys Val Pro Leu 
65                  70                  75                  80  


Met Arg Cys Gly Gly Cys Cys Asn Asp Glu Gly Leu Glu Cys Val Pro 
                85                  90                  95      


Thr Glu Glu Ser Asn Ile Thr Met Gln Ile Met Arg Ile Lys Pro His 
            100                 105                 110         


Gln Gly Gln His Ile Gly Glu Met Ser Phe Leu Gln His Asn Lys Cys 
        115                 120                 125             


Glu Cys Arg Pro Lys Lys Asp Arg Ala Arg Gln Glu Lys Lys Ser Val 
    130                 135                 140                 


Arg Gly Lys Gly Lys Gly Gln Lys Arg Lys Arg Lys Lys Ser Arg Tyr 
145                 150                 155                 160 


Lys Ser Trp Ser Val Tyr Val Gly Ala Arg Cys Cys Leu Met Pro Trp 
                165                 170                 175     


Ser Leu Pro Gly Pro His Pro Cys Gly Pro Cys Ser Glu Arg Arg Lys 
            180                 185                 190         


His Leu Phe Val Gln Asp Pro Gln Thr Cys Lys Cys Ser Cys Lys Asn 
        195                 200                 205             


Thr Asp Ser Arg Cys Lys Ala Arg Gln Leu Glu Leu Asn Glu Arg Thr 
    210                 215                 220                 


Cys Arg Cys Asp Lys Pro Arg Arg 
225                 230         


<210>  95
<211>  207
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  95

Met Ser Pro Leu Leu Arg Arg Leu Leu Leu Ala Ala Leu Leu Gln Leu 
1               5                   10                  15      


Ala Pro Ala Gln Ala Pro Val Ser Gln Pro Asp Ala Pro Gly His Gln 
            20                  25                  30          


Arg Lys Val Val Ser Trp Ile Asp Val Tyr Thr Arg Ala Thr Cys Gln 
        35                  40                  45              


Pro Arg Glu Val Val Val Pro Leu Thr Val Glu Leu Met Gly Thr Val 
    50                  55                  60                  


Ala Lys Gln Leu Val Pro Ser Cys Val Thr Val Gln Arg Cys Gly Gly 
65                  70                  75                  80  


Cys Cys Pro Asp Asp Gly Leu Glu Cys Val Pro Thr Gly Gln His Gln 
                85                  90                  95      


Val Arg Met Gln Ile Leu Met Ile Arg Tyr Pro Ser Ser Gln Leu Gly 
            100                 105                 110         


Glu Met Ser Leu Glu Glu His Ser Gln Cys Glu Cys Arg Pro Lys Lys 
        115                 120                 125             


Lys Asp Ser Ala Val Lys Pro Asp Arg Ala Ala Thr Pro His His Arg 
    130                 135                 140                 


Pro Gln Pro Arg Ser Val Pro Gly Trp Asp Ser Ala Pro Gly Ala Pro 
145                 150                 155                 160 


Ser Pro Ala Asp Ile Thr His Pro Thr Pro Ala Pro Gly Pro Ser Ala 
                165                 170                 175     


His Ala Ala Pro Ser Thr Thr Ser Ala Leu Thr Pro Gly Pro Ala Ala 
            180                 185                 190         


Ala Ala Ala Asp Ala Ala Ala Ser Ser Val Ala Lys Gly Gly Ala 
        195                 200                 205         


<210>  96
<211>  419
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  96

Met His Leu Leu Gly Phe Phe Ser Val Ala Cys Ser Leu Leu Ala Ala 
1               5                   10                  15      


Ala Leu Leu Pro Gly Pro Arg Glu Ala Pro Ala Ala Ala Ala Ala Phe 
            20                  25                  30          


Glu Ser Gly Leu Asp Leu Ser Asp Ala Glu Pro Asp Ala Gly Glu Ala 
        35                  40                  45              


Thr Ala Tyr Ala Ser Lys Asp Leu Glu Glu Gln Leu Arg Ser Val Ser 
    50                  55                  60                  


Ser Val Asp Glu Leu Met Thr Val Leu Tyr Pro Glu Tyr Trp Lys Met 
65                  70                  75                  80  


Tyr Lys Cys Gln Leu Arg Lys Gly Gly Trp Gln His Asn Arg Glu Gln 
                85                  90                  95      


Ala Asn Leu Asn Ser Arg Thr Glu Glu Thr Ile Lys Phe Ala Ala Ala 
            100                 105                 110         


His Tyr Asn Thr Glu Ile Leu Lys Ser Ile Asp Asn Glu Trp Arg Lys 
        115                 120                 125             


Thr Gln Cys Met Pro Arg Glu Val Cys Ile Asp Val Gly Lys Glu Phe 
    130                 135                 140                 


Gly Val Ala Thr Asn Thr Phe Phe Lys Pro Pro Cys Val Ser Val Tyr 
145                 150                 155                 160 


Arg Cys Gly Gly Cys Cys Asn Ser Glu Gly Leu Gln Cys Met Asn Thr 
                165                 170                 175     


Ser Thr Ser Tyr Leu Ser Lys Thr Leu Phe Glu Ile Thr Val Pro Leu 
            180                 185                 190         


Ser Gln Gly Pro Lys Pro Val Thr Ile Ser Phe Ala Asn His Thr Ser 
        195                 200                 205             


Cys Arg Cys Met Ser Lys Leu Asp Val Tyr Arg Gln Val His Ser Ile 
    210                 215                 220                 


Ile Arg Arg Ser Leu Pro Ala Thr Leu Pro Gln Cys Gln Ala Ala Asn 
225                 230                 235                 240 


Lys Thr Cys Pro Thr Asn Tyr Met Trp Asn Asn His Ile Cys Arg Cys 
                245                 250                 255     


Leu Ala Gln Glu Asp Phe Met Phe Ser Ser Asp Ala Gly Asp Asp Ser 
            260                 265                 270         


Thr Asp Gly Phe His Asp Ile Cys Gly Pro Asn Lys Glu Leu Asp Glu 
        275                 280                 285             


Glu Thr Cys Gln Cys Val Cys Arg Ala Gly Leu Arg Pro Ala Ser Cys 
    290                 295                 300                 


Gly Pro His Lys Glu Leu Asp Arg Asn Ser Cys Gln Cys Val Cys Lys 
305                 310                 315                 320 


Asn Lys Leu Phe Pro Ser Gln Cys Gly Ala Asn Arg Glu Phe Asp Glu 
                325                 330                 335     


Asn Thr Cys Gln Cys Val Cys Lys Arg Thr Cys Pro Arg Asn Gln Pro 
            340                 345                 350         


Leu Asn Pro Gly Lys Cys Ala Cys Glu Cys Thr Glu Ser Pro Gln Lys 
        355                 360                 365             


Cys Leu Leu Lys Gly Lys Lys Phe His His Gln Thr Cys Ser Cys Tyr 
    370                 375                 380                 


Arg Arg Pro Cys Thr Asn Arg Gln Lys Ala Cys Glu Pro Gly Phe Ser 
385                 390                 395                 400 


Tyr Ser Glu Glu Val Cys Arg Cys Val Pro Ser Tyr Trp Lys Arg Pro 
                405                 410                 415     


Gln Met Ser 
            


<210>  97
<211>  354
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  97

Met Tyr Arg Glu Trp Val Val Val Asn Val Phe Met Met Leu Tyr Val 
1               5                   10                  15      


Gln Leu Val Gln Gly Ser Ser Asn Glu His Gly Pro Val Lys Arg Ser 
            20                  25                  30          


Ser Gln Ser Thr Leu Glu Arg Ser Glu Gln Gln Ile Arg Ala Ala Ser 
        35                  40                  45              


Ser Leu Glu Glu Leu Leu Arg Ile Thr His Ser Glu Asp Trp Lys Leu 
    50                  55                  60                  


Trp Arg Cys Arg Leu Arg Leu Lys Ser Phe Thr Ser Met Asp Ser Arg 
65                  70                  75                  80  


Ser Ala Ser His Arg Ser Thr Arg Phe Ala Ala Thr Phe Tyr Asp Ile 
                85                  90                  95      


Glu Thr Leu Lys Val Ile Asp Glu Glu Trp Gln Arg Thr Gln Cys Ser 
            100                 105                 110         


Pro Arg Glu Thr Cys Val Glu Val Ala Ser Glu Leu Gly Lys Ser Thr 
        115                 120                 125             


Asn Thr Phe Phe Lys Pro Pro Cys Val Asn Val Phe Arg Cys Gly Gly 
    130                 135                 140                 


Cys Cys Asn Glu Glu Ser Leu Ile Cys Met Asn Thr Ser Thr Ser Tyr 
145                 150                 155                 160 


Ile Ser Lys Gln Leu Phe Glu Ile Ser Val Pro Leu Thr Ser Val Pro 
                165                 170                 175     


Glu Leu Val Pro Val Lys Val Ala Asn His Thr Gly Cys Lys Cys Leu 
            180                 185                 190         


Pro Thr Ala Pro Arg His Pro Tyr Ser Ile Ile Arg Arg Ser Ile Gln 
        195                 200                 205             


Ile Pro Glu Glu Asp Arg Cys Ser His Ser Lys Lys Leu Cys Pro Ile 
    210                 215                 220                 


Asp Met Leu Trp Asp Ser Asn Lys Cys Lys Cys Val Leu Gln Glu Glu 
225                 230                 235                 240 


Asn Pro Leu Ala Gly Thr Glu Asp His Ser His Leu Gln Glu Pro Ala 
                245                 250                 255     


Leu Cys Gly Pro His Met Met Phe Asp Glu Asp Arg Cys Glu Cys Val 
            260                 265                 270         


Cys Lys Thr Pro Cys Pro Lys Asp Leu Ile Gln His Pro Lys Asn Cys 
        275                 280                 285             


Ser Cys Phe Glu Cys Lys Glu Ser Leu Glu Thr Cys Cys Gln Lys His 
    290                 295                 300                 


Lys Leu Phe His Pro Asp Thr Cys Ser Cys Glu Asp Arg Cys Pro Phe 
305                 310                 315                 320 


His Thr Arg Pro Cys Ala Ser Gly Lys Thr Ala Cys Ala Lys His Cys 
                325                 330                 335     


Arg Phe Pro Lys Glu Lys Arg Ala Ala Gln Gly Pro His Ser Arg Lys 
            340                 345                 350         


Asn Pro 
        


<210>  98
<211>  662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from EMCV____EMCV-IRES

<400>  98
uugaaagccg ggggugggag auccggauug ccagucugcu cgauaucgca ggcugggucc       60

gugacuaccc acucccccuu uaauuccgcc ccucucccuc cccccccccu aacguuacug      120

gccgaagccg cuuggaauaa ggccggugug cguuugucua uauguuauuu uccaccauau      180

ugccgucuuu uggcaaugug agggcccgga aaccuggccc ugucuucuug acgagcauuc      240

cuaggggucu uuccccucuc gccaaaggaa ugcaaggucu guugaauguc gugaaggaag      300

caguuccucu ggaagcuucu ugaagacaaa caacgucugu agcgacccuu ugcaggcagc      360

ggaacccccc accuggcgac aggugccucu gcggccaaaa gccacgugua uaagauacac      420

cugcaaaggc ggcacaaccc cagugccacg uugugaguug gauaguugug gaaagaguca      480

aauggcucuc cucaagcgua uucaacaagg ggcugaagga ugcccagaag guaccccauu      540

guaugggauc ugaucugggg ccucggugca caugcuuuac guguguuuag ucgagguuaa      600

aaaacgucua ggccccccga accacgggga cgugguuuuc cuuugaaaaa cacgaugaua      660

au                                                                     662


<210>  99
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  99
auggccguca uggcgccccg aacccucguc cugcuacucu cgggggcucu ggcccugacc       60

cagaccuggg cg                                                           72


<210>  100
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  100
auggaugcaa ugaagagagg gcucugcugu gugcugcugc uguguggagc agucuucguu       60

ucgcccagc                                                               69


<210>  101
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  101
augggggugc acgaaugucc ugccuggcug uggcuucucc ugucccugcu gucgcucccu       60

cugggccucc caguccuggg c                                                 81


<210>  102
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  102
augaaguggg uaaccuuuau uucccuucuu uuucucuuua gcucggcuua uucc             54


<210>  103
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from 
       Artificial____cleavage site-Furin

<400>  103
agaaggcggc gcaagaga                                                     18


<210>  104
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  104
auggacucgg acgagaccgg guucgagcac ucaggacugu ggguuucugu gcuggcuggu       60

cuucugcugg gagccugcca ggcacacccc aucccugacu ccaguccucu ccugcaauuc      120

gggggccaag uccggcagcg guaccucuac acagaugaug cccagcagac agaagcccac      180

cuggagauca gggaggaugg gacggugggg ggcgcugcug accagagccc cgaaagucuc      240

cugcagcuga aagccuugaa gccgggaguu auucaaaucu ugggagucaa gacauccagg      300

uuccugugcc agcggccaga uggggcccug uauggaucgc uccacuuuga cccugaggcc      360

ugcagcuucc gggagcugcu ucuugaggac ggauacaaug uuuaccaguc cgaagcccac      420

ggccucccgc ugcaccugcc agggaacaag uccccacacc gggacccugc accccgagga      480

ccagcucgcu uccugccacu accaggccug ccccccgcac ucccggagcc acccggaauc      540

cuggcccccc agccccccga ugugggcucc ucggacccuc ugagcauggu gggaccuucc      600

cagggccgaa gccccagcua cgcuuccuga                                       630


<210>  105
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  105
auggacucgg acgagaccgg guucgagcac ucaggacugu ggguuucugu gcuggcuggu       60

cuucugcugg gagccugcca ggcacacccc aucccugacu ccaguccucu ccugcaauuc      120

gggggccaag uccggcagcg guaccucuac acagaugaug cccagcagac agaagcccac      180

cuggagauca gggaggaugg gacggugggg ggcgcugcug accagagccc cgaaagucuc      240

cugcagcuga aagccuugaa gccgggaguu auucaaaucu ugggagucaa gacauccagg      300

uuccugugcc agcggccaga uggggcccug uauggaucgc uccacuuuga cccugaggcc      360

ugcagcuucc gggagcugcu ucuugaggac ggauacaaug uuuaccaguc cgaagcccac      420

ggccucccgc ugcaccuccc agggaacaag uccccacacc gggacccugc accccgagga      480

ccagcucgcu uccugccacu accaggccug ccccccgcac ucccggagcc acccggaauc      540

cuggcccccc agccccccga ugugggcucc ucggacccuc ugagcauggu gggaccuucc      600

cagggccgaa gccccagcua cgcuuccuga                                       630


<210>  106
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  106
augcacagcu uuccuccacu gcugcugcug cuguucuggg gugugguguc ucacagcuuc       60

ccagcgacuc uagaaacaca agagcaagau guggacuuag uccagaaaua ccuggaaaaa      120

uacuacaacc ugaagaauga ugggaggcaa guugaaaagc ggagaaauag uggcccagug      180

guugaaaaau ugaagcaaau gcaggaauuc uuugggcuga aagugacugg gaaaccagau      240

gcugaaaccc ugaaggugau gaagcagccc agauguggag ugccugaugu ggcucaguuu      300

guccucacug aggggaaccc ucgcugggag caaacacauc ugaccuacag gauugaaaau      360

uacacgccag auuugccaag agcagaugug gaccaugcca uugagaaagc cuuccaacuc      420

uggaguaaug ucacaccucu gacauucacc aaggucucug agggucaagc agacaucaug      480

auaucuuuug ucaggggaga ucaucgggac aacucuccuu uugauggacc uggaggaaau      540

cuugcucaug cuuuucaacc aggcccaggu auuggagggg augcucauuu ugaugaagau      600

gaaaggugga ccaacaauuu cagagaguac aacuuacauc guguugcagc ucaugaacuc      660

ggccauucuc uuggacucuc ccauucuacu gauaucgggg cuuugaugua cccuagcuac      720

accuucagug gugauguuca gcuagcucag gaugacauug auggcaucca agccauauau      780

ggacguuccc aaaauccugu ccagcccauc ggcccacaaa ccccaaaagc gugugacagu      840

aagcuaaccu uugaugcuau aacuacgauu cggggagaag ugauguucuu uaaagacaga      900

uucuacaugc gcacaaaucc cuucuacccg gaaguugagc ucaauuucau uucuguuuuc      960

uggccacaac ugccaaaugg gcuugaagcu gcuuacgaau uugccgacag agaugaaguc     1020

cgguuuuuca aagggaauaa guacugggcu guucagggac agaaugugcu acacggauac     1080

cccaaggaca ucuacagcuc cuuuggcuuc ccuagaacug ugaagcauau cgaugcugcu     1140

cuuucugagg aaaacacugg aaaaaccuac uucuuuguug cuaacaaaua cuggagguau     1200

gaugaauaua aacgaucuau ggauccaggu uaucccaaaa ugauagcaca ugacuuuccu     1260

ggaauuggcc acaaaguuga ugcaguuuuc augaaagaug gauuuuucua uuucuuucau     1320

ggaacaagac aauacaaauu ugauccuaaa acgaagagaa uuuugacucu ccagaaagcu     1380

aauagcuggu ucaacugcag gaaaaauuga                                      1410


<210>  107
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  107
augcacagcu uuccuccacu gcugcugcug cuguucuggg gugugguguc ucacagcuuc       60

ccagcgacuc uagaaacaca agagcaagau guggacuuag uccagaaaua ccuggaaaaa      120

uacuacaacc ugaagaauga ugggaggcaa guugaaaagc ggagaaauag uggcccagug      180

guugaaaaau ugaagcaaau gcaggaguuc uuugggcuga aagugacugg gaaaccagau      240

gcugaaaccc ugaaggugau gaagcagccc agauguggag ugccugaugu ggcucaguuu      300

guccucacug aggggaaccc ucgcugggag caaacacauc ugaccuacag gauugaaaau      360

uacacgccag auuugccaag agcagaugug gaccaugcca uugagaaagc cuuccaacuc      420

uggaguaaug ucacaccucu gacauucacc aaggucucug agggucaagc agacaucaug      480

auaucuuuug ucaggggaga ucaucgggac aacucuccuu uugauggacc uggaggaaau      540

cuugcucaug cuuuucaacc aggcccaggu auuggagggg augcucauuu ugaugaagau      600

gaaaggugga ccaacaauuu cagagaguac aacuuacauc guguugcagc ucaugaacuc      660

ggccauucuc uuggacucuc ccauucuacu gauaucgggg cuuugaugua cccuagcuac      720

accuucagug gugauguuca gcuagcucag gaugacauug auggcaucca agccauauau      780

ggacguuccc aaaauccugu ccagcccauc ggcccacaaa ccccaaaagc gugugacagu      840

aagcuaaccu uugaugcuau aacuacgauu cggggagaag ugauguucuu uaaagacaga      900

uucuacaugc gcacaaaucc cuucuacccg gaaguugagc ucaauuucau uucuguuuuc      960

uggccacaac ugccaaaugg gcuugaagcu gcuuacgaau uugccgacag agaugaaguc     1020

cgguuuuuca aagggaauaa guacugggcu guucagggac agaaugugcu acacggauac     1080

cccaaggaca ucuacagcuc cuuuggcuuc ccuagaacug ugaagcauau cgaugcugcu     1140

cuuucugagg aaaacacugg aaaaaccuac uucuuuguug cuaacaaaua cuggagguau     1200

gaugaauaua aacgaucuau ggauccaggu uaucccaaaa ugauagcaca ugacuuuccu     1260

ggaauuggcc acaaaguuga ugcaguuuuc augaaagaug gauuuuucua uuucuuucau     1320

ggaacaagac aauacaaauu ugauccuaaa acgaagagaa uuuugacucu ccagaaagcu     1380

aauagcuggu ucaacugcag gaaaaauuga                                      1410


<210>  108
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  108
augcacagcu uuccuccacu gcugcugcug cuguucuggg gugugguguc ucacagcuuu       60

guccucacug aggggaaccc ucgcugggag caaacacauc ugaccuacag gauugaaaau      120

uacacgccag auuugccaag agcagaugug gaccaugcca uugagaaagc cuuccaacuc      180

uggaguaaug ucacaccucu gacauucacc aaggucucug agggucaagc agacaucaug      240

auaucuuuug ucaggggaga ucaucgggac aacucuccuu uugauggacc uggaggaaau      300

cuugcucaug cuuuucaacc aggcccaggu auuggagggg augcucauuu ugaugaagau      360

gaaaggugga ccaacaauuu cagagaguac aacuuacauc guguugcagc ucaugaacuc      420

ggccauucuc uuggacucuc ccauucuacu gauaucgggg cuuugaugua cccuagcuac      480

accuucagug gugauguuca gcuagcucag gaugacauug auggcaucca agccauauau      540

ggacguuccc aaaauccugu ccagcccauc ggcccacaaa ccccaaaagc gugugacagu      600

aagcuaaccu uugaugcuau aacuacgauu cggggagaag ugauguucuu uaaagacaga      660

uucuacaugc gcacaaaucc cuucuacccg gaaguugagc ucaauuucau uucuguuuuc      720

uggccacaac ugccaaaugg gcuugaagcu gcuuacgaau uugccgacag agaugaaguc      780

cgguuuuuca aagggaauaa guacugggcu guucagggac agaaugugcu acacggauac      840

cccaaggaca ucuacagcuc cuuuggcuuc ccuagaacug ugaagcauau cgaugcugcu      900

cuuucugagg aaaacacugg aaaaaccuac uucuuuguug cuaacaaaua cuggagguau      960

gaugaauaua aacgaucuau ggauccaggu uaucccaaaa ugauagcaca ugacuuuccu     1020

ggaauuggcc acaaaguuga ugcaguuuuc augaaagaug gauuuuucua uuucuuucau     1080

ggaacaagac aauacaaauu ugauccuaaa acgaagagaa uuuugacucu ccagaaagcu     1140

aauagcuggu ucaacugcag gaaaaauuga                                      1170


<210>  109
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  109
augaaaaaaa auauuuuaaa gauucuuaug gauaguuauu cuaaagaauc uaaaauucaa       60

acuguacgua ggguuacgag uguaucacuu uuagcgguau aucuuacuau gaauacuuca      120

aguuuaguuu uagcaaaacc aauagaaaau acuaaugaua cuaguauaaa aaauguggag      180

aaauuaagaa augcuccaaa ugaagagaau aguaaaaagg uagaagauag uaaaaaugau      240

aagguagaac augugaaaaa uauagaagag gcaaagguug agcaaguugc acccgaagua      300

aaaucuaaau caacuuuaag aagugcuucu auagcgaaua cuaauucuga gaaauaugau      360

uuugaguauu uaaaugguuu gagcuauacu gaacuuacaa auuuaauuaa aaauauaaag      420

uggaaucaaa uuaaugguuu auuuaauuau aguacagguu cucaaaaguu cuuuggagau      480

aaaaaucgug uacaagcuau aauuaaugcu uuacaagaaa guggaagaac uuacacugca      540

aaugauauga aggguauaga aacuuucacu gagguuuuaa gagcugguuu uuauuuaggg      600

uacuauaaug augguuuauc uuauuuaaau gauagaaacu uccaagauaa auguauaccu      660

gcaaugauug caauucaaaa aaauccuaac uuuaagcuag gaacugcagu ucaagaugaa      720

guuauaacuu cuuuaggaaa acuaauagga aaugcuucug cuaaugcuga aguaguuaau      780

aauuguguac caguucuaaa acaauuuaga gaaaacuuaa aucaauaugc uccugauuac      840

guuaaaggaa cagcuguaaa ugaauuaauu aaagguauug aauucgauuu uucuggugcu      900

gcauaugaaa aagauguuaa gacaaugccu ugguauggaa aaauugaucc auuuauaaau      960

gaacuuaagg ccuuaggucu auauggaaau auaacaagug caacugagug ggcaucugau     1020

guuggaauau acuauuuaag uaaauucggu cuuuacucaa cuaaccgaaa ugacauagua     1080

cagucacuug aaaaggcugu agauauguau aaguauggua aaauagccuu uguagcaaug     1140

gagagaauaa cuugggauua ugaugggauu gguucuaaug guaaaaaggu ggaucacgau     1200

aaguucuuag augaugcuga aaaacauuau cugccaaaga cauauacuuu ugauaaugga     1260

accuuuauua uaagagcagg ggauaaggua uccgaagaaa aaauaaaaag gcuauauugg     1320

gcaucaagag aagugaaguc ucaauuccau agaguaguug gcaaugauaa agcuuuagag     1380

gugggaaaug ccgaugaugu uuuaacuaug aaaauauuua auagcccaga agaauauaaa     1440

uuuaauacca auauaaaugg uguaagcacu gauaauggug gucuauauau agaaccaaga     1500

gggacuuucu acacuuauga gagaacaccu caacaaagua uauuuagucu ugaagaauug     1560

uuuagacaug aauauacuca cuauuuacaa gcgagauauc uuguagaugg uuuauggggg     1620

caagguccau uuuaugaaaa aaauagauua acuugguuug augaagguac agcugaauuc     1680

uuugcaggau cuacccguac aucugguguu uuaccaagaa aaucaauauu aggauauuug     1740

gcuaaggaua aaguagauca uagauacuca uuaaagaaga cucuuaauuc aggguaugau     1800

gacagugauu ggauguucua uaauuaugga uuugcaguug cacauuaccu auaugaaaaa     1860

gauaugccua cauuuauuaa gaugaauaaa gcuauauuga auacagaugu gaaaucuuau     1920

gaugaaauaa uaaaaaaauu aagugaugau gcaaauaaaa auacagaaua ucaaaaccau     1980

auucaagagu uagcagauaa auaucaagga gcaggcauac cucuaguauc agaugauuac     2040

uuaaaagauc auggauauaa gaaagcaucu gaaguauauu cugaaauuuc aaaagcugcu     2100

ucucuuacaa acacuagugu aacagcagaa aaaucucaau auuuuaacac auucacuuua     2160

agaggaacuu auacagguga aacuucuaaa ggugaauuua aagauuggga ugaaaugagu     2220

aaaaaauuag auggaacuuu ggagucccuu gcuaaaaauu cuuggagugg auacaaaacu     2280

uuaacagcau acuuuacgaa uuauagaguu acaagcgaua auaaaguuca auaugaugua     2340

guuuuccaug ggguuuuaac agauaaugcg gauauuagua acaauaaggc uccaauagca     2400

aagguaacug gaccaagcac uggugcugua ggaagaaaua uugaauuuag uggaaaagau     2460

aguaaagaug aagaugguaa aauaguauca uaugauuggg auuuuggcga uggugcaacu     2520

aguagaggca aaaauucagu acaugcuuac aaaaaagcag gaacauauaa uguuacauua     2580

aaaguaacug acgauaaggg ugcaacagcu acagaaagcu uuacuauaga aauaaagaac     2640

gaagauacaa caacaccuau aacuaaagaa auggaaccua augaugauau aaaagaggcu     2700

aaugguccaa uaguugaagg uguuacugua aaaggugauu uaaaugguuc ugaugaugcu     2760

gauaccuucu auuuugaugu aaaagaagau ggugauguua caauugaacu uccuuauuca     2820

gggucaucua auuucacaug guuaguuuau aaagagggag acgaucaaaa ccauauugca     2880

agugguauag auaagaauaa cucaaaaguu ggaacauuua aaucuacaaa aggaagacau     2940

uauguguuua uauauaaaca cgauucugcu ucaaauauau ccuauucuuu aaacauaaaa     3000

ggauuaggua acgagaaauu gaaggaaaaa gaaaauaaug auucuucuga uaaagcuaca     3060

guuauaccaa auuucaauac cacuaugcaa gguucacuuu uaggugauga uucaagagau     3120

uauuauucuu uugagguuaa ggaagaaggc gaaguuaaua uagaacuaga uaaaaaggau     3180

gaauuuggug uaacauggac acuacaucca gagucaaaua uuaaugacag aauaacuuac     3240

ggacaaguug augguaauaa gguaucuaau aaaguuaaau uaagaccagg aaaauauuau     3300

cuacuuguuu auaaauacuc aggaucagga aacuaugagu uaaggguaaa uaaauaa        3357


<210>  110
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  110
augaaaaaaa auauuuuaaa gauucuuaug gauaguuauu cuaaagaauc uaaaauucaa       60

acuguacgua ggguuacgag uguaucacuu uuagcgguau aucuuacuau gaauacuuca      120

aguuuaguuu uagcaaaacc aauagaaaau acuaaugaua caaguauaaa aaauguggag      180

aaauuaagaa augcuccaaa ugaagagaau aguaaaaagg uagaagauag uaaaaaugau      240

aagguagaac augugaaaaa uauagaagag gcaaagguug agcaaguugc acccgaagua      300

aaaucuaaau caacuuuaag aagugcuucu auagcgaaua cuaauucuga gaaauaugau      360

uuugaguauu uaaaugguuu gagcuauacu gaacuuacaa auuuaauuaa aaauauaaag      420

uggaaucaaa uuaaugguuu auuuaauuau aguacagguu cucaaaaguu cuuuggagau      480

aaaaaucgug uacaagcuau aauuaaugcu uuacaagaaa guggaagaac uuacacugca      540

aaugauauga aggguauaga aacuuucacu gagguuuuaa gagcugguuu uuauuuaggg      600

uacuauaaug augguuuauc uuauuuaaau gauagaaacu uccaagauaa auguauaccu      660

gcaaugauug caauucaaaa aaauccuaac uuuaagcuag gaacugcagu ucaagaugaa      720

guuauaacuu cuuuaggaaa acuaauagga aaugcuucug cuaaugcuga aguaguuaau      780

aauuguguac caguucuaaa acaauuuaga gaaaacuuaa aucaauaugc uccugauuac      840

guuaaaggaa cagcuguaaa ugaauuaauu aaagguauug aguucgauuu uucuggugcu      900

gcauaugaaa aagauguuaa gacaaugccu ugguauggaa aaauugaucc auuuauaaau      960

gaacuuaagg ccuuaggucu auauggaaau auaacaagug caacugagug ggcaucugau     1020

guuggaauau acuauuuaag uaaauucggu cuuuacucaa cuaaccgaaa ugacauagua     1080

cagucacuug aaaaggcugu agauauguau aaguauggua aaauagccuu uguagcaaug     1140

gagagaauaa cuugggauua ugaugggauu gguucuaaug guaaaaaggu ggaucacgau     1200

aaguucuuag augaugcuga aaaacauuau cugccaaaga cauauacuuu ugauaaugga     1260

accuuuauua uaagagcagg ggauaaggua uccgaagaaa aaauaaaaag gcuauauugg     1320

gcaucaagag aagugaaguc ucaauuccau agaguaguug gcaaugauaa agcauuagag     1380

gugggaaaug ccgaugaugu uuuaacuaug aaaauauuua auagcccaga agaauauaaa     1440

uuuaauacca auauaaaugg uguaagcacu gauaauggug gucuauauau agaaccaaga     1500

gggacuuucu acacuuauga gagaacaccu caacaaagua uauuuagucu ugaagaauug     1560

uuuagacaug aauauacuca cuauuuacaa gcgagauauc uuguagaugg uuuauggggg     1620

caagguccau uuuaugaaaa aaauagauua acuugguuug augaagguac agcugaguuc     1680

uuugcaggau cuacccguac aucugguguu uuaccaagaa aaucaauauu aggauauuug     1740

gcuaaggaua aaguagauca uagauacuca uuaaagaaga cucuuaauuc aggguaugau     1800

gacagugauu ggauguucua uaauuaugga uuugcaguug cacauuaccu auaugaaaaa     1860

gauaugccua cauuuauuaa gaugaauaaa gcuauauuga auacagaugu gaaaucuuau     1920

gaugaaauaa uaaaaaaauu aagugaugau gcaaauaaaa auacagaaua ucaaaaccau     1980

auucaagagu uagcagauaa auaucaagga gcaggcauac cucuaguauc agaugauuac     2040

uuaaaagauc auggauauaa gaaagcaucu gaaguauauu cugaaauuuc aaaagcugcu     2100

ucucuuacaa acacaagugu aacagcagaa aaaucucaau auuuuaacac auucacuuua     2160

agaggaacuu auacagguga aacuucuaaa ggugaauuua aagauuggga ugaaaugagu     2220

aaaaaauuag auggaacuuu ggagucccuu gcuaaaaauu cuuggagugg auacaaaacu     2280

uuaacagcau acuuuacgaa uuauagaguu acaagcgaua auaaaguuca auaugaugua     2340

guuuuccaug ggguuuuaac agauaaugcg gauauuagua acaauaaggc uccaauagca     2400

aagguaacug gaccaagcac uggugcugua ggaagaaaua uugaauuuag uggaaaagau     2460

aguaaagaug aagaugguaa aauaguauca uaugauuggg auuuuggcga uggugcaaca     2520

aguagaggca aaaauucagu acaugcuuac aaaaaagcag gaacauauaa uguuacauua     2580

aaaguaacug acgauaaggg ugcaacagcu acagagagcu uuacuauaga aauaaagaac     2640

gaagauacaa caacaccuau aacuaaagaa auggaaccua augaugauau aaaagaggcu     2700

aaugguccaa uaguugaagg uguuacugua aaaggugauu uaaaugguuc ugaugaugcu     2760

gauaccuucu auuuugaugu aaaagaagau ggugauguua caauugaacu uccuuauuca     2820

gggucaucua auuucacaug guuaguuuau aaagagggag acgaucaaaa ccauauugca     2880

agugguauag auaagaauaa cucaaaaguu ggaacauuua aaucuacaaa aggaagacau     2940

uauguguuua uauauaaaca cgauucugcu ucaaauauau ccuauucuuu aaacauaaaa     3000

ggauuaggua acgagaaauu gaaggaaaaa gaaaauaaug auucuucuga uaaagcuaca     3060

guuauaccaa auuucaauac cacuaugcaa gguucacuuu uaggugauga uucaagagau     3120

uauuauucuu uugagguuaa ggaagaaggc gaaguuaaua uagaacuaga uaaaaaggau     3180

gaauuuggug uaacauggac acuacaucca gagucaaaua uuaaugacag aauaacuuac     3240

ggacaaguug augguaauaa gguaucuaau aaaguuaaau uaagaccagg aaaauauuau     3300

cuacuuguuu auaaauacuc aggaucagga aacuaugagu uaaggguaaa uaaauaa        3357


<210>  111
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  111
augaaguggg uaaccuuuau uucccuucuu uuucucuuua gcucggcuua uuccauagcg       60

aauacuaauu cugagaaaua ugauuuugag uauuuaaaug guuugagcua uacugaacuu      120

acaaauuuaa uuaaaaauau aaaguggaau caaauuaaug guuuauuuaa uuauaguaca      180

gguucucaaa aguucuuugg agauaaaaau cguguacaag cuauaauuaa ugcuuuacaa      240

gaaaguggaa gaacuuacac ugcaaaugau augaagggua uagaaacuuu cacugagguu      300

uuaagagcug guuuuuauuu aggguacuau aaugaugguu uaucuuauuu aaaugauaga      360

aacuuccaag auaaauguau accugcaaug auugcaauuc aaaaaaaucc uaacuuuaag      420

cuaggaacug caguucaaga ugaaguuaua acuucuuuag gaaaacuaau aggaaaugcu      480

ucugcuaaug cugaaguagu uaauaauugu guaccaguuc uaaaacaauu uagagaaaac      540

uuaaaucaau augcuccuga uuacguuaaa ggaacagcug uaaaugaauu aauuaaaggu      600

auugaauucg auuuuucugg ugcugcauau gaaaaagaug uuaagacaau gccuugguau      660

ggaaaaauug auccauuuau aaaugaacuu aaggccuuag gucuauaugg aaauauaaca      720

agugcaacug agugggcauc ugauguugga auauacuauu uaaguaaauu cggucuuuac      780

ucaacuaacc gaaaugacau aguacaguca cuugaaaagg cuguagauau guauaaguau      840

gguaaaauag ccuuuguagc aauggagaga auaacuuggg auuaugaugg gauugguucu      900

aaugguaaaa agguggauca cgauaaguuc uuagaugaug cugaaaaaca uuaucugcca      960

aagacauaua cuuuugauaa uggaaccuuu auuauaagag caggggauaa gguauccgaa     1020

gaaaaaauaa aaaggcuaua uugggcauca agagaaguga agucucaauu ccauagagua     1080

guuggcaaug auaaagcuuu agagguggga aaugccgaug auguuuuaac uaugaaaaua     1140

uuuaauagcc cagaagaaua uaaauuuaau accaauauaa augguguaag cacugauaau     1200

gguggucuau auauagaacc aagagggacu uucuacacuu augagagaac accucaacaa     1260

aguauauuua gucuugaaga auuguuuaga caugaauaua cucacuauuu acaagcgaga     1320

uaucuuguag augguuuaug ggggcaaggu ccauuuuaug aaaaaaauag auuaacuugg     1380

uuugaugaag guacagcuga auucuuugca ggaucuaccc guacaucugg uguuuuacca     1440

agaaaaucaa uauuaggaua uuuggcuaag gauaaaguag aucauagaua cucauuaaag     1500

aagacucuua auucagggua ugaugacagu gauuggaugu ucuauaauua uggauuugca     1560

guugcacauu accuauauga aaaagauaug ccuacauuua uuaagaugaa uaaagcuaua     1620

uugaauacag augugaaauc uuaugaugaa auaauaaaaa aauuaaguga ugaugcaaau     1680

aaaaauacag aauaucaaaa ccauauucaa gaguuagcag auaaauauca aggagcaggc     1740

auaccucuag uaucagauga uuacuuaaaa gaucauggau auaagaaagc aucugaagua     1800

uauucugaaa uuucaaaagc ugcuucucuu acaaacacua guguaacagc agaaaaaucu     1860

caauauuuua acacauucac uuuaagagga acuuauacag gugaaacuuc uaaaggugaa     1920

uuuaaagauu gggaugaaau gaguaaaaaa uuagauggaa cuuuggaguc ccuugcuaaa     1980

aauucuugga guggauacaa aacuuuaaca gcauacuuua cgaauuauag aguuacaagc     2040

gauaauaaag uucaauauga uguaguuuuc caugggguuu uaacagauaa ugcggauauu     2100

aguaacaaua aggcuccaau agcaaaggua acuggaccaa gcacuggugc uguaggaaga     2160

aauauugaau uuaguggaaa agauaguaaa gaugaagaug guaaaauagu aucauaugau     2220

ugggauuuug gcgauggugc aacuaguaga ggcaaaaauu caguacaugc uuacaaaaaa     2280

gcaggaacau auaauguuac auuaaaagua acugacgaua agggugcaac agcuacagaa     2340

agcuuuacua uagaaauaaa gaacgaagau acaacaacac cuauaacuaa agaaauggaa     2400

ccuaaugaug auauaaaaga ggcuaauggu ccaauaguug aagguguuac uguaaaaggu     2460

gauuuaaaug guucugauga ugcugauacc uucuauuuug auguaaaaga agauggugau     2520

guuacaauug aacuuccuua uucaggguca ucuaauuuca caugguuagu uuauaaagag     2580

ggagacgauc aaaaccauau ugcaaguggu auagauaaga auaacucaaa aguuggaaca     2640

uuuaaaucua caaaaggaag acauuaugug uuuauauaua aacacgauuc ugcuucaaau     2700

auauccuauu cuuuaaacau aaaaggauua gguaacgaga aauugaagga aaaagaaaau     2760

aaugauucuu cugauaaagc uacaguuaua ccaaauuuca auaccacuau gcaagguuca     2820

cuuuuaggug augauucaag agauuauuau ucuuuugagg uuaaggaaga aggcgaaguu     2880

aauauagaac uagauaaaaa ggaugaauuu gguguaacau ggacacuaca uccagaguca     2940

aauauuaaug acagaauaac uuacggacaa guugauggua auaagguauc uaauaaaguu     3000

aaauuaagac caggaaaaua uuaucuacuu guuuauaaau acucaggauc aggaaacuau     3060

gaguuaaggg uaaauaaaua a                                               3081


<210>  112
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  112
augaaguggg uaaccuuuau uucccuucuu uuucucuuua gcucggcuua uuccauagcg       60

aauacuaauu cugagaaaua ugauuuugag uauuuaaaug guuugagcua uacugaacuu      120

acaaauuuaa uuaaaaauau aaaguggaau caaauuaaug guuuauuuaa uuauaguaca      180

gguucucaaa aguucuuugg agauaaaaau cguguacaag cuauaauuaa ugcuuuacaa      240

gaaaguggaa gaacuuacac ugcaaaugau augaagggua uagaaacuuu cacugagguu      300

uuaagagcug guuuuuauuu aggguacuau aaugaugguu uaucuuauuu aaaugauaga      360

aacuuccaag auaaauguau accugcaaug auugcaauuc aaaaaaaucc uaacuuuaag      420

cuaggaacug caguucaaga ugaaguuaua acuucuuuag gaaaacuaau aggaaaugcu      480

ucugcuaaug cugaaguagu uaauaauugu guaccaguuc uaaaacaauu uagagaaaac      540

uuaaaucaau augcuccuga uuacguuaaa ggaacagcug uaaaugaauu aauuaaaggu      600

auugaguucg auuuuucugg ugcugcauau gaaaaagaug uuaagacaau gccuugguau      660

ggaaaaauug auccauuuau aaaugaacuu aaggccuuag gucuauaugg aaauauaaca      720

agugcaacug agugggcauc ugauguugga auauacuauu uaaguaaauu cggucuuuac      780

ucaacuaacc gaaaugacau aguacaguca cuugaaaagg cuguagauau guauaaguau      840

gguaaaauag ccuuuguagc aauggagaga auaacuuggg auuaugaugg gauugguucu      900

aaugguaaaa agguggauca cgauaaguuc uuagaugaug cugaaaaaca uuaucugcca      960

aagacauaua cuuuugauaa uggaaccuuu auuauaagag caggggauaa gguauccgaa     1020

gaaaaaauaa aaaggcuaua uugggcauca agagaaguga agucucaauu ccauagagua     1080

guuggcaaug auaaagcauu agagguggga aaugccgaug auguuuuaac uaugaaaaua     1140

uuuaauagcc cagaagaaua uaaauuuaau accaauauaa augguguaag cacugauaau     1200

gguggucuau auauagaacc aagagggacu uucuacacuu augagagaac accucaacaa     1260

aguauauuua gucuugaaga auuguuuaga caugaauaua cucacuauuu acaagcgaga     1320

uaucuuguag augguuuaug ggggcaaggu ccauuuuaug aaaaaaauag auuaacuugg     1380

uuugaugaag guacagcuga guucuuugca ggaucuaccc guacaucugg uguuuuacca     1440

agaaaaucaa uauuaggaua uuuggcuaag gauaaaguag aucauagaua cucauuaaag     1500

aagacucuua auucagggua ugaugacagu gauuggaugu ucuauaauua uggauuugca     1560

guugcacauu accuauauga aaaagauaug ccuacauuua uuaagaugaa uaaagcuaua     1620

uugaauacag augugaaauc uuaugaugaa auaauaaaaa aauuaaguga ugaugcaaau     1680

aaaaauacag aauaucaaaa ccauauucaa gaguuagcag auaaauauca aggagcaggc     1740

auaccucuag uaucagauga uuacuuaaaa gaucauggau auaagaaagc aucugaagua     1800

uauucugaaa uuucaaaagc ugcuucucuu acaaacacaa guguaacagc agaaaaaucu     1860

caauauuuua acacauucac uuuaagagga acuuauacag gugaaacuuc uaaaggugaa     1920

uuuaaagauu gggaugaaau gaguaaaaaa uuagauggaa cuuuggaguc ccuugcuaaa     1980

aauucuugga guggauacaa aacuuuaaca gcauacuuua cgaauuauag aguuacaagc     2040

gauaauaaag uucaauauga uguaguuuuc caugggguuu uaacagauaa ugcggauauu     2100

aguaacaaua aggcuccaau agcaaaggua acuggaccaa gcacuggugc uguaggaaga     2160

aauauugaau uuaguggaaa agauaguaaa gaugaagaug guaaaauagu aucauaugau     2220

ugggauuuug gcgauggugc aacaaguaga ggcaaaaauu caguacaugc uuacaaaaaa     2280

gcaggaacau auaauguuac auuaaaagua acugacgaua agggugcaac agcuacagag     2340

agcuuuacua uagaaauaaa gaacgaagau acaacaacac cuauaacuaa agaaauggaa     2400

ccuaaugaug auauaaaaga ggcuaauggu ccaauaguug aagguguuac uguaaaaggu     2460

gauuuaaaug guucugauga ugcugauacc uucuauuuug auguaaaaga agauggugau     2520

guuacaauug aacuuccuua uucaggguca ucuaauuuca caugguuagu uuauaaagag     2580

ggagacgauc aaaaccauau ugcaaguggu auagauaaga auaacucaaa aguuggaaca     2640

uuuaaaucua caaaaggaag acauuaugug uuuauauaua aacacgauuc ugcuucaaau     2700

auauccuauu cuuuaaacau aaaaggauua gguaacgaga aauugaagga aaaagaaaau     2760

aaugauucuu cugauaaagc uacaguuaua ccaaauuuca auaccacuau gcaagguuca     2820

cuuuuaggug augauucaag agauuauuau ucuuuugagg uuaaggaaga aggcgaaguu     2880

aauauagaac uagauaaaaa ggaugaauuu gguguaacau ggacacuaca uccagaguca     2940

aauauuaaug acagaauaac uuacggacaa guugauggua auaagguauc uaauaaaguu     3000

aaauuaagac caggaaaaua uuaucuacuu guuuauaaau acucaggauc aggaaacuau     3060

gaguuaaggg uaaauaaaua a                                               3081


<210>  113
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  113
augaaguggg uaaccuuuau uucccuucuu uuucucuuua gcucggcuua uuccaugaaa       60

aaaaauauuu uaaagauucu uauggauagu uauucuaaag aaucuaaaau ucaaacugua      120

cguaggguua cgaguguauc acuuuuagcg guauaucuua cuaugaauac uucaaguuua      180

guuuuagcaa aaccaauaga aaauacuaau gauacuagua uaaaaaaugu ggagaaauua      240

agaaaugcuc caaaugaaga gaauaguaaa aagguagaag auaguaaaaa ugauaaggua      300

gaacauguga aaaauauaga agaggcaaag guugagcaag uugcacccga aguaaaaucu      360

aaaucaacuu uaagaagugc uucuagaagg cggcgcaaga gaauagcgaa uacuaauucu      420

gagaaauaug auuuugagua uuuaaauggu uugagcuaua cugaacuuac aaauuuaauu      480

aaaaauauaa aguggaauca aauuaauggu uuauuuaauu auaguacagg uucucaaaag      540

uucuuuggag auaaaaaucg uguacaagcu auaauuaaug cuuuacaaga aaguggaaga      600

acuuacacug caaaugauau gaaggguaua gaaacuuuca cugagguuuu aagagcuggu      660

uuuuauuuag gguacuauaa ugaugguuua ucuuauuuaa augauagaaa cuuccaagau      720

aaauguauac cugcaaugau ugcaauucaa aaaaauccua acuuuaagcu aggaacugca      780

guucaagaug aaguuauaac uucuuuagga aaacuaauag gaaaugcuuc ugcuaaugcu      840

gaaguaguua auaauugugu accaguucua aaacaauuua gagaaaacuu aaaucaauau      900

gcuccugauu acguuaaagg aacagcugua aaugaauuaa uuaaagguau ugaauucgau      960

uuuucuggug cugcauauga aaaagauguu aagacaaugc cuugguaugg aaaaauugau     1020

ccauuuauaa augaacuuaa ggccuuaggu cuauauggaa auauaacaag ugcaacugag     1080

ugggcaucug auguuggaau auacuauuua aguaaauucg gucuuuacuc aacuaaccga     1140

aaugacauag uacagucacu ugaaaaggcu guagauaugu auaaguaugg uaaaauagcc     1200

uuuguagcaa uggagagaau aacuugggau uaugauggga uugguucuaa ugguaaaaag     1260

guggaucacg auaaguucuu agaugaugcu gaaaaacauu aucugccaaa gacauauacu     1320

uuugauaaug gaaccuuuau uauaagagca ggggauaagg uauccgaaga aaaaauaaaa     1380

aggcuauauu gggcaucaag agaagugaag ucucaauucc auagaguagu uggcaaugau     1440

aaagcuuuag aggugggaaa ugccgaugau guuuuaacua ugaaaauauu uaauagccca     1500

gaagaauaua aauuuaauac caauauaaau gguguaagca cugauaaugg uggucuauau     1560

auagaaccaa gagggacuuu cuacacuuau gagagaacac cucaacaaag uauauuuagu     1620

cuugaagaau uguuuagaca ugaauauacu cacuauuuac aagcgagaua ucuuguagau     1680

gguuuauggg ggcaaggucc auuuuaugaa aaaaauagau uaacuugguu ugaugaaggu     1740

acagcugaau ucuuugcagg aucuacccgu acaucuggug uuuuaccaag aaaaucaaua     1800

uuaggauauu uggcuaagga uaaaguagau cauagauacu cauuaaagaa gacucuuaau     1860

ucaggguaug augacaguga uuggauguuc uauaauuaug gauuugcagu ugcacauuac     1920

cuauaugaaa aagauaugcc uacauuuauu aagaugaaua aagcuauauu gaauacagau     1980

gugaaaucuu augaugaaau aauaaaaaaa uuaagugaug augcaaauaa aaauacagaa     2040

uaucaaaacc auauucaaga guuagcagau aaauaucaag gagcaggcau accucuagua     2100

ucagaugauu acuuaaaaga ucauggauau aagaaagcau cugaaguaua uucugaaauu     2160

ucaaaagcug cuucucuuac aaacacuagu guaacagcag aaaaaucuca auauuuuaac     2220

acauucacuu uaagaggaac uuauacaggu gaaacuucua aaggugaauu uaaagauugg     2280

gaugaaauga guaaaaaauu agauggaacu uuggaguccc uugcuaaaaa uucuuggagu     2340

ggauacaaaa cuuuaacagc auacuuuacg aauuauagag uuacaagcga uaauaaaguu     2400

caauaugaug uaguuuucca ugggguuuua acagauaaug cggauauuag uaacaauaag     2460

gcuccaauag caaagguaac uggaccaagc acuggugcug uaggaagaaa uauugaauuu     2520

aguggaaaag auaguaaaga ugaagauggu aaaauaguau cauaugauug ggauuuuggc     2580

gauggugcaa cuaguagagg caaaaauuca guacaugcuu acaaaaaagc aggaacauau     2640

aauguuacau uaaaaguaac ugacgauaag ggugcaacag cuacagaaag cuuuacuaua     2700

gaaauaaaga acgaagauac aacaacaccu auaacuaaag aaauggaacc uaaugaugau     2760

auaaaagagg cuaauggucc aauaguugaa gguguuacug uaaaagguga uuuaaauggu     2820

ucugaugaug cugauaccuu cuauuuugau guaaaagaag auggugaugu uacaauugaa     2880

cuuccuuauu cagggucauc uaauuucaca ugguuaguuu auaaagaggg agacgaucaa     2940

aaccauauug caagugguau agauaagaau aacucaaaag uuggaacauu uaaaucuaca     3000

aaaggaagac auuauguguu uauauauaaa cacgauucug cuucaaauau auccuauucu     3060

uuaaacauaa aaggauuagg uaacgagaaa uugaaggaaa aagaaaauaa ugauucuucu     3120

gauaaagcua caguuauacc aaauuucaau accacuaugc aagguucacu uuuaggugau     3180

gauucaagag auuauuauuc uuuugagguu aaggaagaag gcgaaguuaa uauagaacua     3240

gauaaaaagg augaauuugg uguaacaugg acacuacauc cagagucaaa uauuaaugac     3300

agaauaacuu acggacaagu ugaugguaau aagguaucua auaaaguuaa auuaagacca     3360

ggaaaauauu aucuacuugu uuauaaauac ucaggaucag gaaacuauga guuaagggua     3420

aauaaauaa                                                             3429


<210>  114
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  114
augaaguggg uaaccuuuau uucccuucuu uuucucuuua gcucggcuua uuccaugaaa       60

aaaaauauuu uaaagauucu uauggauagu uauucuaaag aaucuaaaau ucaaacugua      120

cguaggguua cgaguguauc acuuuuagcg guauaucuua cuaugaauac uucaaguuua      180

guuuuagcaa aaccaauaga aaauacuaau gauacaagua uaaaaaaugu ggagaaauua      240

agaaaugcuc caaaugaaga gaauaguaaa aagguagaag auaguaaaaa ugauaaggua      300

gaacauguga aaaauauaga agaggcaaag guugagcaag uugcacccga aguaaaaucu      360

aaaucaacuu uaagaagugc uucuagaagg cggcgcaaga gaauagcgaa uacuaauucu      420

gagaaauaug auuuugagua uuuaaauggu uugagcuaua cugaacuuac aaauuuaauu      480

aaaaauauaa aguggaauca aauuaauggu uuauuuaauu auaguacagg uucucaaaag      540

uucuuuggag auaaaaaucg uguacaagcu auaauuaaug cuuuacaaga aaguggaaga      600

acuuacacug caaaugauau gaaggguaua gaaacuuuca cugagguuuu aagagcuggu      660

uuuuauuuag gguacuauaa ugaugguuua ucuuauuuaa augauagaaa cuuccaagau      720

aaauguauac cugcaaugau ugcaauucaa aaaaauccua acuuuaagcu aggaacugca      780

guucaagaug aaguuauaac uucuuuagga aaacuaauag gaaaugcuuc ugcuaaugcu      840

gaaguaguua auaauugugu accaguucua aaacaauuua gagaaaacuu aaaucaauau      900

gcuccugauu acguuaaagg aacagcugua aaugaauuaa uuaaagguau ugaguucgau      960

uuuucuggug cugcauauga aaaagauguu aagacaaugc cuugguaugg aaaaauugau     1020

ccauuuauaa augaacuuaa ggccuuaggu cuauauggaa auauaacaag ugcaacugag     1080

ugggcaucug auguuggaau auacuauuua aguaaauucg gucuuuacuc aacuaaccga     1140

aaugacauag uacagucacu ugaaaaggcu guagauaugu auaaguaugg uaaaauagcc     1200

uuuguagcaa uggagagaau aacuugggau uaugauggga uugguucuaa ugguaaaaag     1260

guggaucacg auaaguucuu agaugaugcu gaaaaacauu aucugccaaa gacauauacu     1320

uuugauaaug gaaccuuuau uauaagagca ggggauaagg uauccgaaga aaaaauaaaa     1380

aggcuauauu gggcaucaag agaagugaag ucucaauucc auagaguagu uggcaaugau     1440

aaagcauuag aggugggaaa ugccgaugau guuuuaacua ugaaaauauu uaauagccca     1500

gaagaauaua aauuuaauac caauauaaau gguguaagca cugauaaugg uggucuauau     1560

auagaaccaa gagggacuuu cuacacuuau gagagaacac cucaacaaag uauauuuagu     1620

cuugaagaau uguuuagaca ugaauauacu cacuauuuac aagcgagaua ucuuguagau     1680

gguuuauggg ggcaaggucc auuuuaugaa aaaaauagau uaacuugguu ugaugaaggu     1740

acagcugagu ucuuugcagg aucuacccgu acaucuggug uuuuaccaag aaaaucaaua     1800

uuaggauauu uggcuaagga uaaaguagau cauagauacu cauuaaagaa gacucuuaau     1860

ucaggguaug augacaguga uuggauguuc uauaauuaug gauuugcagu ugcacauuac     1920

cuauaugaaa aagauaugcc uacauuuauu aagaugaaua aagcuauauu gaauacagau     1980

gugaaaucuu augaugaaau aauaaaaaaa uuaagugaug augcaaauaa aaauacagaa     2040

uaucaaaacc auauucaaga guuagcagau aaauaucaag gagcaggcau accucuagua     2100

ucagaugauu acuuaaaaga ucauggauau aagaaagcau cugaaguaua uucugaaauu     2160

ucaaaagcug cuucucuuac aaacacaagu guaacagcag aaaaaucuca auauuuuaac     2220

acauucacuu uaagaggaac uuauacaggu gaaacuucua aaggugaauu uaaagauugg     2280

gaugaaauga guaaaaaauu agauggaacu uuggaguccc uugcuaaaaa uucuuggagu     2340

ggauacaaaa cuuuaacagc auacuuuacg aauuauagag uuacaagcga uaauaaaguu     2400

caauaugaug uaguuuucca ugggguuuua acagauaaug cggauauuag uaacaauaag     2460

gcuccaauag caaagguaac uggaccaagc acuggugcug uaggaagaaa uauugaauuu     2520

aguggaaaag auaguaaaga ugaagauggu aaaauaguau cauaugauug ggauuuuggc     2580

gauggugcaa caaguagagg caaaaauuca guacaugcuu acaaaaaagc aggaacauau     2640

aauguuacau uaaaaguaac ugacgauaag ggugcaacag cuacagagag cuuuacuaua     2700

gaaauaaaga acgaagauac aacaacaccu auaacuaaag aaauggaacc uaaugaugau     2760

auaaaagagg cuaauggucc aauaguugaa gguguuacug uaaaagguga uuuaaauggu     2820

ucugaugaug cugauaccuu cuauuuugau guaaaagaag auggugaugu uacaauugaa     2880

cuuccuuauu cagggucauc uaauuucaca ugguuaguuu auaaagaggg agacgaucaa     2940

aaccauauug caagugguau agauaagaau aacucaaaag uuggaacauu uaaaucuaca     3000

aaaggaagac auuauguguu uauauauaaa cacgauucug cuucaaauau auccuauucu     3060

uuaaacauaa aaggauuagg uaacgagaaa uugaaggaaa aagaaaauaa ugauucuucu     3120

gauaaagcua caguuauacc aaauuucaau accacuaugc aagguucacu uuuaggugau     3180

gauucaagag auuauuauuc uuuugagguu aaggaagaag gcgaaguuaa uauagaacua     3240

gauaaaaagg augaauuugg uguaacaugg acacuacauc cagagucaaa uauuaaugac     3300

agaauaacuu acggacaagu ugaugguaau aagguaucua auaaaguuaa auuaagacca     3360

ggaaaauauu aucuacuugu uuauaaauac ucaggaucag gaaacuauga guuaagggua     3420

aauaaauaa                                                             3429


<210>  115
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  115
augaauuuuu uaaaaauuau uuuaaauagg gggaagacua ugaaaaggaa auguuuaucu       60

aaaaggcuua uguuagcuau aacaauggcu acaauauuua cagugaacag uacauuacca      120

auuuaugcag cuguagauaa aaauaaugca acagcagcug uacaaaauga aaguaagagg      180

uauacaguau cauauuuaaa gacuuuaaau uauuaugacu uaguagauuu gcuuguuaag      240

acugaaauug agaauuuacc agaccuuuuu caguauaguu cagaugcaaa agaguucuau      300

ggaaauaaaa cucguaugag cuuuaucaug gaugaaauug guagaagggc accucaguau      360

acagagauag aucauaaagg uauuccuacu uuaguagaag uuguaagagc uggauuuuac      420

uuaggauucc auaacaagga auugaaugaa auaaacaaga ggucuuuuaa agaaagggua      480

auaccuucua uauuagcaau ucaaaaaaau ccuaauuuua aacuagguac ugaaguucaa      540

gauaaaauag uaucugcaac aggacuuuua gcugguaaug aaacagcgcc uccagaaguu      600

guaaauaauu uuacaccaau acuucaagac uguauaaaga auauagacag auacgcucuu      660

gaugauuuaa agucaaaagc auuauuuaau guuuuagcug caccuaccua ugauauaacu      720

gaguauuuaa gagcuacuaa agaaaaacca gaaaacacuc cuugguaugg uaaaauagau      780

ggguuuauaa augaacuuaa aaaguuagcu cuuuauggaa aaauaaauga uaauaacucu      840

uggauaauag auaacgguau auaucauaua gcaccuuuag ggaaguuaca uagcaauaau      900

aaaauaggaa uagaaacuuu aacagagguu augaaaguuu auccuuauuu aaguaugcaa      960

cauuuacaau cagcagauca aauuaagcgu cauuaugauu caaaagaugc ugaaggaaac     1020

aaaauaccuu uagauaaguu uaaaaaggaa ggaaaagaaa aauacugucc aaaaacuuau     1080

acauuugaug auggaaaagu aauaauaaaa gcuggugcua gaguagaaga agaaaaaguu     1140

aaaagacuau acugggcauc aaaggaaguu aacucucaau ucuuuagagu auacggaaua     1200

gacaaaccau uagaagaagg uaauccagau gauauauuaa caaugguuau cuacaacagu     1260

cccgaagaau auaaacucaa uaguguucua uacggauaug auacuaauaa uggugguaug     1320

uauauagagc cagaaggaac uuucuucacc uaugaaagag aagcucaaga aagcacauac     1380

acauuagaag aauuauuuag acaugaauau acacauuauu ugcaaggaag auaugcaguu     1440

ccaggacaau ggggaagaac aaaacuuuau gacaaugaua gauuaacuug guaugaagaa     1500

gguggagcag aauuauuugc agguucuacu agaacuucug gaauauuacc aagaaagagu     1560

auaguaucaa auauucauaa uacaacaaga aauaauagau auaagcuuuc agacacugua     1620

cauucuaaau auggugcuag uuuugaauuc uauaauuaug cauguauguu uauggauuau     1680

auguauaaua aagauauggg uauauuaaau aaacuaaaug aucuugcaaa aaauaaugau     1740

guugauggau augauaauua uauuagagau uuaaguucua auuaugcuuu aaaugauaaa     1800

uaucaagauc auaugcagga gcgcauagau aauuaugaaa auuuaacagu gccuuuugua     1860

gcugaugauu auuuaguaag gcaugcuuau aagaacccua augaaauuua uucugaaaua     1920

ucugaaguag caaaauuaaa ggaugcuaag agugaaguua agaaaucaca auauuuuagu     1980

accuuuacuu ugagagguag uuacacaggu ggagcaucua aggggaaauu agaagaucaa     2040

aaagcaauga auaaguuuau agaugauuca cuuaagaaau uagauacgua uucuuggagu     2100

ggguauaaaa cuuuaacugc uuauuucacu aauuauaaag uugacucuuc aaauagaguu     2160

acuuaugaug uaguauucca cggauauuua ccaaacgaag gugauuccaa aaauucauua     2220

ccuuauggca agaucaaugg aacuuacaag ggaacagaga aagaaaaaau caaauucucu     2280

agugaaggcu cuuucgaucc agaugguaaa auaguuucuu augaauggga uuucggagau     2340

gguaauaaga guaaugagga aaauccagag cauucauaug acaagguagg aacuuauaca     2400

gugaaauuaa aaguuacuga ugacaaggga gaaucuucag uaucuacuac uacugcagaa     2460

auaaaggauc uuucagaaaa uaaacuucca guuauauaua ugcauguacc uaaauccgga     2520

gccuuaaauc aaaaaguugu uuucuaugga aaaggaacau augacccaga uggaucuauc     2580

gcaggauauc aaugggacuu uggugaugga agugauuuua gcagugaaca aaacccaagc     2640

cauguauaua cuaaaaaagg ugaauauacu guaacauuaa gaguaaugga uaguagugga     2700

caaaugagug aaaaaacuau gaagauuaag auuacagauc cgguauaucc aauaggcacu     2760

gaaaaagaac caaauaacag uaaagaaacu gcaagugguc caauaguacc agguauaccu     2820

guuaguggaa ccauagaaaa uacaagugau caagauuauu ucuauuuuga uguuauaaca     2880

ccaggagaag uaaaaauaga uauaaauaaa uuaggguacg gaggagcuac uuggguagua     2940

uaugaugaaa auaauaaugc aguaucuuau gccacugaug augggcaaaa uuuaagugga     3000

aaguuuaagg cagauaaacc agguagauau uacauccauc uuuacauguu uaaugguagu     3060

uauaugccau auagaauuaa uauagaaggu ucaguaggaa gauaa                     3105


<210>  116
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  116
augaauuuuu uaaaaauuau uuuaaauagg gggaagacua ugaaaaggaa auguuuaucu       60

aaaaggcuua uguuagcuau aacaauggcu acaauauuua cagugaacag uacauuacca      120

auuuaugcag cuguagauaa aaauaaugca acagcagcug uacaaaauga aaguaagagg      180

uauacaguau cauauuuaaa gacuuuaaau uauuaugacu uaguagauuu gcuuguuaag      240

acugaaauug agaauuuacc agaccuuuuu caguauaguu cagaugcaaa agaguucuau      300

ggaaauaaaa cucguaugag cuuuaucaug gaugaaauug guagaagggc accucaguau      360

acagagauag aucauaaagg uauuccuacu uuaguagaag uuguaagagc uggauuuuac      420

uuaggauucc auaacaagga auugaaugaa auaaacaaga ggucuuuuaa agaaagggua      480

auaccuucua uauuagcaau ucaaaaaaau ccuaauuuua aacuagguac ugaaguucaa      540

gauaaaauag uaucugcaac aggacuuuua gcugguaaug aaacagcgcc uccagaaguu      600

guaaauaauu uuacaccaau acuucaagac uguauaaaga auauagacag auacgcucuu      660

gaugauuuaa agucaaaagc auuauuuaau guuuuagcug caccuaccua ugauauaacu      720

gaguauuuaa gagcuacuaa agaaaaacca gaaaacacuc cuugguaugg uaaaauagau      780

ggguuuauaa augaacuuaa aaaguuagcu cuuuauggaa aaauaaauga uaauaacucu      840

uggauaauag auaacgguau auaucauaua gcaccuuuag ggaaguuaca uagcaauaau      900

aaaauaggaa uagaaacuuu aacagagguu augaaaguuu auccuuauuu aaguaugcaa      960

cauuuacaau cagcagauca aauuaagcgu cauuaugauu caaaagaugc ugaaggaaac     1020

aaaauaccuu uagauaaguu uaaaaaggaa ggaaaagaaa aauacugucc aaaaacuuau     1080

acauuugaug auggaaaagu aauaauaaaa gcuggugcua gaguagaaga agaaaaaguu     1140

aaaagacuau acugggcauc aaaggaaguu aacucucaau ucuuuagagu auacggaaua     1200

gacaaaccau uagaagaagg uaauccagau gauauauuaa caaugguuau cuacaacagu     1260

cccgaagaau auaaacucaa uaguguucua uacggauaug auacuaauaa uggugguaug     1320

uauauagagc cagaaggaac uuucuucacc uaugaaagag aagcucaaga aagcacauac     1380

acauuagaag aauuauuuag acaugaauau acacauuauu ugcaaggaag auaugcaguu     1440

ccaggacaau ggggaagaac aaaacuuuau gacaaugaua gauuaacuug guaugaagaa     1500

gguggagcag aauuauuugc agguucuacu agaacuucug gaauauuacc aagaaagagu     1560

auaguaucaa auauucauaa uacaacaaga aauaauagau auaagcuguc agacacugua     1620

cauucuaaau auggugcuag uuuugaguuc uauaauuaug cauguauguu uauggauuau     1680

auguauaaua aagauauggg uauauuaaau aaacuaaaug aucuugcaaa aaauaaugau     1740

guugauggau augauaauua uauuagagau uuaaguucua auuaugcuuu aaaugauaaa     1800

uaucaagauc auaugcagga gcgcauagau aauuaugaaa auuuaacagu gccuuuugua     1860

gcugaugauu auuuaguaag gcaugcuuau aagaacccua augaaauuua uucugaaaua     1920

ucugaaguag caaaauuaaa ggaugcuaag agugaaguua agaaaucaca auauuuuagu     1980

accuuuacuu ugagagguag uuacacaggu ggagcaucua aggggaaauu agaagaucaa     2040

aaagcaauga auaaguuuau agaugauuca cuuaagaaau uagauacgua uucuuggagu     2100

ggguauaaaa cuuuaacugc uuauuucacu aauuauaaag uugacucuuc aaauagaguu     2160

acuuaugaug uaguauucca cggauauuua ccaaacgaag gugauuccaa aaauucauua     2220

ccuuauggca agaucaaugg aacuuacaag ggaacagaga aagaaaaaau caaauucucu     2280

agugaaggcu cuuucgaucc agaugguaaa auaguuucuu augaauggga uuucggagau     2340

gguaauaaga guaaugagga aaauccagag cauucauaug acaagguagg aacuuauaca     2400

gugaaauuaa aaguuacuga ugacaaggga gaaucuucag uaucuacuac uacugcagaa     2460

auaaaggauc uuucagaaaa uaaacuucca guuauauaua ugcauguacc uaaauccgga     2520

gccuuaaauc aaaaaguugu uuucuaugga aaaggaacau augacccaga uggaucuauc     2580

gcaggauauc aaugggacuu uggugaugga agugauuuua gcagugaaca aaacccaagc     2640

cauguauaua cuaaaaaagg ugaauauacu guaacauuaa gaguaaugga uaguagugga     2700

caaaugagug aaaaaacuau gaagauuaag auuacagauc cgguauaucc aauaggcacu     2760

gaaaaagaac caaauaacag uaaagaaacu gcaagugguc caauaguacc agguauaccu     2820

guuaguggaa ccauagaaaa uacaagugau caagauuauu ucuauuuuga uguuauaaca     2880

ccaggagaag uaaaaauaga uauaaauaaa uuaggguacg gaggagcuac uuggguagua     2940

uaugaugaaa auaauaaugc aguaucuuau gccacugaug augggcaaaa uuuaagugga     3000

aaguuuaagg cagauaaacc agguagauau uacauccauc uuuacauguu uaaugguagu     3060

uauaugccau auagaauuaa uauagaaggu ucaguaggaa gauaa                     3105


<210>  117
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  117
augaaaagga aauguuuauc uaaaaggcuu auguuagcua uaacaauggc uacaauauuu       60

acagugaaca guacauuacc aauuuaugca gcuguagaua aaaauaaugc aacagcagcu      120

guacaaaaug aaaguaagag guauacagua ucauauuuaa agacuuuaaa uuauuaugac      180

uuaguagauu ugcuuguuaa gacugaaauu gagaauuuac cagaccuuuu ucaguauagu      240

ucagaugcaa aagaguucua uggaaauaaa acucguauga gcuuuaucau ggaugaaauu      300

gguagaaggg caccucagua uacagagaua gaucauaaag guauuccuac uuuaguagaa      360

guuguaagag cuggauuuua cuuaggauuc cauaacaagg aauugaauga aauaaacaag      420

aggucuuuua aagaaagggu aauaccuucu auauuagcaa uucaaaaaaa uccuaauuuu      480

aaacuaggua cugaaguuca agauaaaaua guaucugcaa caggacuuuu agcugguaau      540

gaaacagcgc cuccagaagu uguaaauaau uuuacaccaa uacuucaaga cuguauaaag      600

aauauagaca gauacgcucu ugaugauuua aagucaaaag cauuauuuaa uguuuuagcu      660

gcaccuaccu augauauaac ugaguauuua agagcuacua aagaaaaacc agaaaacacu      720

ccuugguaug guaaaauaga uggguuuaua aaugaacuua aaaaguuagc ucuuuaugga      780

aaaauaaaug auaauaacuc uuggauaaua gauaacggua uauaucauau agcaccuuua      840

gggaaguuac auagcaauaa uaaaauagga auagaaacuu uaacagaggu uaugaaaguu      900

uauccuuauu uaaguaugca acauuuacaa ucagcagauc aaauuaagcg ucauuaugau      960

ucaaaagaug cugaaggaaa caaaauaccu uuagauaagu uuaaaaagga aggaaaagaa     1020

aaauacuguc caaaaacuua uacauuugau gauggaaaag uaauaauaaa agcuggugcu     1080

agaguagaag aagaaaaagu uaaaagacua uacugggcau caaaggaagu uaacucucaa     1140

uucuuuagag uauacggaau agacaaacca uuagaagaag guaauccaga ugauauauua     1200

acaaugguua ucuacaacag ucccgaagaa uauaaacuca auaguguucu auacggauau     1260

gauacuaaua auggugguau guauauagag ccagaaggaa cuuucuucac cuaugaaaga     1320

gaagcucaag aaagcacaua cacauuagaa gaauuauuua gacaugaaua uacacauuau     1380

uugcaaggaa gauaugcagu uccaggacaa uggggaagaa caaaacuuua ugacaaugau     1440

agauuaacuu gguaugaaga agguggagca gaauuauuug cagguucuac uagaacuucu     1500

ggaauauuac caagaaagag uauaguauca aauauucaua auacaacaag aaauaauaga     1560

uauaagcuuu cagacacugu acauucuaaa uauggugcua guuuugaauu cuauaauuau     1620

gcauguaugu uuauggauua uauguauaau aaagauaugg guauauuaaa uaaacuaaau     1680

gaucuugcaa aaaauaauga uguugaugga uaugauaauu auauuagaga uuuaaguucu     1740

aauuaugcuu uaaaugauaa auaucaagau cauaugcagg agcgcauaga uaauuaugaa     1800

aauuuaacag ugccuuuugu agcugaugau uauuuaguaa ggcaugcuua uaagaacccu     1860

aaugaaauuu auucugaaau aucugaagua gcaaaauuaa aggaugcuaa gagugaaguu     1920

aagaaaucac aauauuuuag uaccuuuacu uugagaggua guuacacagg uggagcaucu     1980

aaggggaaau uagaagauca aaaagcaaug aauaaguuua uagaugauuc acuuaagaaa     2040

uuagauacgu auucuuggag uggguauaaa acuuuaacug cuuauuucac uaauuauaaa     2100

guugacucuu caaauagagu uacuuaugau guaguauucc acggauauuu accaaacgaa     2160

ggugauucca aaaauucauu accuuauggc aagaucaaug gaacuuacaa gggaacagag     2220

aaagaaaaaa ucaaauucuc uagugaaggc ucuuucgauc cagaugguaa aauaguuucu     2280

uaugaauggg auuucggaga ugguaauaag aguaaugagg aaaauccaga gcauucauau     2340

gacaagguag gaacuuauac agugaaauua aaaguuacug augacaaggg agaaucuuca     2400

guaucuacua cuacugcaga aauaaaggau cuuucagaaa auaaacuucc aguuauauau     2460

augcauguac cuaaauccgg agccuuaaau caaaaaguug uuuucuaugg aaaaggaaca     2520

uaugacccag auggaucuau cgcaggauau caaugggacu uuggugaugg aagugauuuu     2580

agcagugaac aaaacccaag ccauguauau acuaaaaaag gugaauauac uguaacauua     2640

agaguaaugg auaguagugg acaaaugagu gaaaaaacua ugaagauuaa gauuacagau     2700

ccgguauauc caauaggcac ugaaaaagaa ccaaauaaca guaaagaaac ugcaaguggu     2760

ccaauaguac cagguauacc uguuagugga accauagaaa auacaaguga ucaagauuau     2820

uucuauuuug auguuauaac accaggagaa guaaaaauag auauaaauaa auuaggguac     2880

ggaggagcua cuuggguagu auaugaugaa aauaauaaug caguaucuua ugccacugau     2940

gaugggcaaa auuuaagugg aaaguuuaag gcagauaaac cagguagaua uuacauccau     3000

cuuuacaugu uuaaugguag uuauaugcca uauagaauua auauagaagg uucaguagga     3060

agauaa                                                                3066


<210>  118
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  118
augaaaagga aauguuuauc uaaaaggcuu auguuagcua uaacaauggc uacaauauuu       60

acagugaaca guacauuacc aauuuaugca gcuguagaua aaaauaaugc aacagcagcu      120

guacaaaaug aaaguaagag guauacagua ucauauuuaa agacuuuaaa uuauuaugac      180

uuaguagauu ugcuuguuaa gacugaaauu gagaauuuac cagaccuuuu ucaguauagu      240

ucagaugcaa aagaguucua uggaaauaaa acucguauga gcuuuaucau ggaugaaauu      300

gguagaaggg caccucagua uacagagaua gaucauaaag guauuccuac uuuaguagaa      360

guuguaagag cuggauuuua cuuaggauuc cauaacaagg aauugaauga aauaaacaag      420

aggucuuuua aagaaagggu aauaccuucu auauuagcaa uucaaaaaaa uccuaauuuu      480

aaacuaggua cugaaguuca agauaaaaua guaucugcaa caggacuuuu agcugguaau      540

gaaacagcgc cuccagaagu uguaaauaau uuuacaccaa uacuucaaga cuguauaaag      600

aauauagaca gauacgcucu ugaugauuua aagucaaaag cauuauuuaa uguuuuagcu      660

gcaccuaccu augauauaac ugaguauuua agagcuacua aagaaaaacc agaaaacacu      720

ccuugguaug guaaaauaga uggguuuaua aaugaacuua aaaaguuagc ucuuuaugga      780

aaaauaaaug auaauaacuc uuggauaaua gauaacggua uauaucauau agcaccuuua      840

gggaaguuac auagcaauaa uaaaauagga auagaaacuu uaacagaggu uaugaaaguu      900

uauccuuauu uaaguaugca acauuuacaa ucagcagauc aaauuaagcg ucauuaugau      960

ucaaaagaug cugaaggaaa caaaauaccu uuagauaagu uuaaaaagga aggaaaagaa     1020

aaauacuguc caaaaacuua uacauuugau gauggaaaag uaauaauaaa agcuggugcu     1080

agaguagaag aagaaaaagu uaaaagacua uacugggcau caaaggaagu uaacucucaa     1140

uucuuuagag uauacggaau agacaaacca uuagaagaag guaauccaga ugauauauua     1200

acaaugguua ucuacaacag ucccgaagaa uauaaacuca auaguguucu auacggauau     1260

gauacuaaua auggugguau guauauagag ccagaaggaa cuuucuucac cuaugaaaga     1320

gaagcucaag aaagcacaua cacauuagaa gaauuauuua gacaugaaua uacacauuau     1380

uugcaaggaa gauaugcagu uccaggacaa uggggaagaa caaaacuuua ugacaaugau     1440

agauuaacuu gguaugaaga agguggagca gaauuauuug cagguucuac uagaacuucu     1500

ggaauauuac caagaaagag uauaguauca aauauucaua auacaacaag aaauaauaga     1560

uauaagcugu cagacacugu acauucuaaa uauggugcua guuuugaguu cuauaauuau     1620

gcauguaugu uuauggauua uauguauaau aaagauaugg guauauuaaa uaaacuaaau     1680

gaucuugcaa aaaauaauga uguugaugga uaugauaauu auauuagaga uuuaaguucu     1740

aauuaugcuu uaaaugauaa auaucaagau cauaugcagg agcgcauaga uaauuaugaa     1800

aauuuaacag ugccuuuugu agcugaugau uauuuaguaa ggcaugcuua uaagaacccu     1860

aaugaaauuu auucugaaau aucugaagua gcaaaauuaa aggaugcuaa gagugaaguu     1920

aagaaaucac aauauuuuag uaccuuuacu uugagaggua guuacacagg uggagcaucu     1980

aaggggaaau uagaagauca aaaagcaaug aauaaguuua uagaugauuc acuuaagaaa     2040

uuagauacgu auucuuggag uggguauaaa acuuuaacug cuuauuucac uaauuauaaa     2100

guugacucuu caaauagagu uacuuaugau guaguauucc acggauauuu accaaacgaa     2160

ggugauucca aaaauucauu accuuauggc aagaucaaug gaacuuacaa gggaacagag     2220

aaagaaaaaa ucaaauucuc uagugaaggc ucuuucgauc cagaugguaa aauaguuucu     2280

uaugaauggg auuucggaga ugguaauaag aguaaugagg aaaauccaga gcauucauau     2340

gacaagguag gaacuuauac agugaaauua aaaguuacug augacaaggg agaaucuuca     2400

guaucuacua cuacugcaga aauaaaggau cuuucagaaa auaaacuucc aguuauauau     2460

augcauguac cuaaauccgg agccuuaaau caaaaaguug uuuucuaugg aaaaggaaca     2520

uaugacccag auggaucuau cgcaggauau caaugggacu uuggugaugg aagugauuuu     2580

agcagugaac aaaacccaag ccauguauau acuaaaaaag gugaauauac uguaacauua     2640

agaguaaugg auaguagugg acaaaugagu gaaaaaacua ugaagauuaa gauuacagau     2700

ccgguauauc caauaggcac ugaaaaagaa ccaaauaaca guaaagaaac ugcaaguggu     2760

ccaauaguac cagguauacc uguuagugga accauagaaa auacaaguga ucaagauuau     2820

uucuauuuug auguuauaac accaggagaa guaaaaauag auauaaauaa auuaggguac     2880

ggaggagcua cuuggguagu auaugaugaa aauaauaaug caguaucuua ugccacugau     2940

gaugggcaaa auuuaagugg aaaguuuaag gcagauaaac cagguagaua uuacauccau     3000

cuuuacaugu uuaaugguag uuauaugcca uauagaauua auauagaagg uucaguagga     3060

agauaa                                                                3066


<210>  119
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  119
augaaguggg uaaccuuuau uucccuucuu uuucucuuua gcucggcuua uuccguacaa       60

aaugaaagua agagguauac aguaucauau uuaaagacuu uaaauuauua ugacuuagua      120

gauuugcuug uuaagacuga aauugagaau uuaccagacc uuuuucagua uaguucagau      180

gcaaaagagu ucuauggaaa uaaaacucgu augagcuuua ucauggauga aauugguaga      240

agggcaccuc aguauacaga gauagaucau aaagguauuc cuacuuuagu agaaguugua      300

agagcuggau uuuacuuagg auuccauaac aaggaauuga augaaauaaa caagaggucu      360

uuuaaagaaa ggguaauacc uucuauauua gcaauucaaa aaaauccuaa uuuuaaacua      420

gguacugaag uucaagauaa aauaguaucu gcaacaggac uuuuagcugg uaaugaaaca      480

gcgccuccag aaguuguaaa uaauuuuaca ccaauacuuc aagacuguau aaagaauaua      540

gacagauacg cucuugauga uuuaaaguca aaagcauuau uuaauguuuu agcugcaccu      600

accuaugaua uaacugagua uuuaagagcu acuaaagaaa aaccagaaaa cacuccuugg      660

uaugguaaaa uagauggguu uauaaaugaa cuuaaaaagu uagcucuuua uggaaaaaua      720

aaugauaaua acucuuggau aauagauaac gguauauauc auauagcacc uuuagggaag      780

uuacauagca auaauaaaau aggaauagaa acuuuaacag agguuaugaa aguuuauccu      840

uauuuaagua ugcaacauuu acaaucagca gaucaaauua agcgucauua ugauucaaaa      900

gaugcugaag gaaacaaaau accuuuagau aaguuuaaaa aggaaggaaa agaaaaauac      960

uguccaaaaa cuuauacauu ugaugaugga aaaguaauaa uaaaagcugg ugcuagagua     1020

gaagaagaaa aaguuaaaag acuauacugg gcaucaaagg aaguuaacuc ucaauucuuu     1080

agaguauacg gaauagacaa accauuagaa gaagguaauc cagaugauau auuaacaaug     1140

guuaucuaca acagucccga agaauauaaa cucaauagug uucuauacgg auaugauacu     1200

aauaauggug guauguauau agagccagaa ggaacuuucu ucaccuauga aagagaagcu     1260

caagaaagca cauacacauu agaagaauua uuuagacaug aauauacaca uuauuugcaa     1320

ggaagauaug caguuccagg acaaugggga agaacaaaac uuuaugacaa ugauagauua     1380

acuugguaug aagaaggugg agcagaauua uuugcagguu cuacuagaac uucuggaaua     1440

uuaccaagaa agaguauagu aucaaauauu cauaauacaa caagaaauaa uagauauaag     1500

cuuucagaca cuguacauuc uaaauauggu gcuaguuuug aauucuauaa uuaugcaugu     1560

auguuuaugg auuauaugua uaauaaagau auggguauau uaaauaaacu aaaugaucuu     1620

gcaaaaaaua augauguuga uggauaugau aauuauauua gagauuuaag uucuaauuau     1680

gcuuuaaaug auaaauauca agaucauaug caggagcgca uagauaauua ugaaaauuua     1740

acagugccuu uuguagcuga ugauuauuua guaaggcaug cuuauaagaa cccuaaugaa     1800

auuuauucug aaauaucuga aguagcaaaa uuaaaggaug cuaagaguga aguuaagaaa     1860

ucacaauauu uuaguaccuu uacuuugaga gguaguuaca cagguggagc aucuaagggg     1920

aaauuagaag aucaaaaagc aaugaauaag uuuauagaug auucacuuaa gaaauuagau     1980

acguauucuu ggagugggua uaaaacuuua acugcuuauu ucacuaauua uaaaguugac     2040

ucuucaaaua gaguuacuua ugauguagua uuccacggau auuuaccaaa cgaaggugau     2100

uccaaaaauu cauuaccuua uggcaagauc aauggaacuu acaagggaac agagaaagaa     2160

aaaaucaaau ucucuaguga aggcucuuuc gauccagaug guaaaauagu uucuuaugaa     2220

ugggauuucg gagaugguaa uaagaguaau gaggaaaauc cagagcauuc auaugacaag     2280

guaggaacuu auacagugaa auuaaaaguu acugaugaca agggagaauc uucaguaucu     2340

acuacuacug cagaaauaaa ggaucuuuca gaaaauaaac uuccaguuau auauaugcau     2400

guaccuaaau ccggagccuu aaaucaaaaa guuguuuucu auggaaaagg aacauaugac     2460

ccagauggau cuaucgcagg auaucaaugg gacuuuggug auggaaguga uuuuagcagu     2520

gaacaaaacc caagccaugu auauacuaaa aaaggugaau auacuguaac auuaagagua     2580

auggauagua guggacaaau gagugaaaaa acuaugaaga uuaagauuac agauccggua     2640

uauccaauag gcacugaaaa agaaccaaau aacaguaaag aaacugcaag ugguccaaua     2700

guaccaggua uaccuguuag uggaaccaua gaaaauacaa gugaucaaga uuauuucuau     2760

uuugauguua uaacaccagg agaaguaaaa auagauauaa auaaauuagg guacggagga     2820

gcuacuuggg uaguauauga ugaaaauaau aaugcaguau cuuaugccac ugaugauggg     2880

caaaauuuaa guggaaaguu uaaggcagau aaaccaggua gauauuacau ccaucuuuac     2940

auguuuaaug guaguuauau gccauauaga auuaauauag aagguucagu aggaagauaa     3000


<210>  120
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  120
augaaguggg uaaccuuuau uucccuucuu uuucucuuua gcucggcuua uuccguacaa       60

aaugaaagua agagguauac aguaucauau uuaaagacuu uaaauuauua ugacuuagua      120

gauuugcuug uuaagacuga aauugagaau uuaccagacc uuuuucagua uaguucagau      180

gcaaaagagu ucuauggaaa uaaaacucgu augagcuuua ucauggauga aauugguaga      240

agggcaccuc aguauacaga gauagaucau aaagguauuc cuacuuuagu agaaguugua      300

agagcuggau uuuacuuagg auuccauaac aaggaauuga augaaauaaa caagaggucu      360

uuuaaagaaa ggguaauacc uucuauauua gcaauucaaa aaaauccuaa uuuuaaacua      420

gguacugaag uucaagauaa aauaguaucu gcaacaggac uuuuagcugg uaaugaaaca      480

gcgccuccag aaguuguaaa uaauuuuaca ccaauacuuc aagacuguau aaagaauaua      540

gacagauacg cucuugauga uuuaaaguca aaagcauuau uuaauguuuu agcugcaccu      600

accuaugaua uaacugagua uuuaagagcu acuaaagaaa aaccagaaaa cacuccuugg      660

uaugguaaaa uagauggguu uauaaaugaa cuuaaaaagu uagcucuuua uggaaaaaua      720

aaugauaaua acucuuggau aauagauaac gguauauauc auauagcacc uuuagggaag      780

uuacauagca auaauaaaau aggaauagaa acuuuaacag agguuaugaa aguuuauccu      840

uauuuaagua ugcaacauuu acaaucagca gaucaaauua agcgucauua ugauucaaaa      900

gaugcugaag gaaacaaaau accuuuagau aaguuuaaaa aggaaggaaa agaaaaauac      960

uguccaaaaa cuuauacauu ugaugaugga aaaguaauaa uaaaagcugg ugcuagagua     1020

gaagaagaaa aaguuaaaag acuauacugg gcaucaaagg aaguuaacuc ucaauucuuu     1080

agaguauacg gaauagacaa accauuagaa gaagguaauc cagaugauau auuaacaaug     1140

guuaucuaca acagucccga agaauauaaa cucaauagug uucuauacgg auaugauacu     1200

aauaauggug guauguauau agagccagaa ggaacuuucu ucaccuauga aagagaagcu     1260

caagaaagca cauacacauu agaagaauua uuuagacaug aauauacaca uuauuugcaa     1320

ggaagauaug caguuccagg acaaugggga agaacaaaac uuuaugacaa ugauagauua     1380

acuugguaug aagaaggugg agcagaauua uuugcagguu cuacuagaac uucuggaaua     1440

uuaccaagaa agaguauagu aucaaauauu cauaauacaa caagaaauaa uagauauaag     1500

cugucagaca cuguacauuc uaaauauggu gcuaguuuug aguucuauaa uuaugcaugu     1560

auguuuaugg auuauaugua uaauaaagau auggguauau uaaauaaacu aaaugaucuu     1620

gcaaaaaaua augauguuga uggauaugau aauuauauua gagauuuaag uucuaauuau     1680

gcuuuaaaug auaaauauca agaucauaug caggagcgca uagauaauua ugaaaauuua     1740

acagugccuu uuguagcuga ugauuauuua guaaggcaug cuuauaagaa cccuaaugaa     1800

auuuauucug aaauaucuga aguagcaaaa uuaaaggaug cuaagaguga aguuaagaaa     1860

ucacaauauu uuaguaccuu uacuuugaga gguaguuaca cagguggagc aucuaagggg     1920

aaauuagaag aucaaaaagc aaugaauaag uuuauagaug auucacuuaa gaaauuagau     1980

acguauucuu ggagugggua uaaaacuuua acugcuuauu ucacuaauua uaaaguugac     2040

ucuucaaaua gaguuacuua ugauguagua uuccacggau auuuaccaaa cgaaggugau     2100

uccaaaaauu cauuaccuua uggcaagauc aauggaacuu acaagggaac agagaaagaa     2160

aaaaucaaau ucucuaguga aggcucuuuc gauccagaug guaaaauagu uucuuaugaa     2220

ugggauuucg gagaugguaa uaagaguaau gaggaaaauc cagagcauuc auaugacaag     2280

guaggaacuu auacagugaa auuaaaaguu acugaugaca agggagaauc uucaguaucu     2340

acuacuacug cagaaauaaa ggaucuuuca gaaaauaaac uuccaguuau auauaugcau     2400

guaccuaaau ccggagccuu aaaucaaaaa guuguuuucu auggaaaagg aacauaugac     2460

ccagauggau cuaucgcagg auaucaaugg gacuuuggug auggaaguga uuuuagcagu     2520

gaacaaaacc caagccaugu auauacuaaa aaaggugaau auacuguaac auuaagagua     2580

auggauagua guggacaaau gagugaaaaa acuaugaaga uuaagauuac agauccggua     2640

uauccaauag gcacugaaaa agaaccaaau aacaguaaag aaacugcaag ugguccaaua     2700

guaccaggua uaccuguuag uggaaccaua gaaaauacaa gugaucaaga uuauuucuau     2760

uuugauguua uaacaccagg agaaguaaaa auagauauaa auaaauuagg guacggagga     2820

gcuacuuggg uaguauauga ugaaaauaau aaugcaguau cuuaugccac ugaugauggg     2880

caaaauuuaa guggaaaguu uaaggcagau aaaccaggua gauauuacau ccaucuuuac     2940

auguuuaaug guaguuauau gccauauaga auuaauauag aagguucagu aggaagauaa     3000


<210>  121
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  121
augaaguggg uaaccuuuau uucccuucuu uuucucuuua gcucggcuua uuccaugaaa       60

aggaaauguu uaucuaaaag gcuuauguua gcuauaacaa uggcuacaau auuuacagug      120

aacaguacau uaccaauuua ugcagcugua gauaaaaaua augcaacagc agcuagaagg      180

cggcgcaaga gaguacaaaa ugaaaguaag agguauacag uaucauauuu aaagacuuua      240

aauuauuaug acuuaguaga uuugcuuguu aagacugaaa uugagaauuu accagaccuu      300

uuucaguaua guucagaugc aaaagaguuc uauggaaaua aaacucguau gagcuuuauc      360

auggaugaaa uugguagaag ggcaccucag uauacagaga uagaucauaa agguauuccu      420

acuuuaguag aaguuguaag agcuggauuu uacuuaggau uccauaacaa ggaauugaau      480

gaaauaaaca agaggucuuu uaaagaaagg guaauaccuu cuauauuagc aauucaaaaa      540

aauccuaauu uuaaacuagg uacugaaguu caagauaaaa uaguaucugc aacaggacuu      600

uuagcuggua augaaacagc gccuccagaa guuguaaaua auuuuacacc aauacuucaa      660

gacuguauaa agaauauaga cagauacgcu cuugaugauu uaaagucaaa agcauuauuu      720

aauguuuuag cugcaccuac cuaugauaua acugaguauu uaagagcuac uaaagaaaaa      780

ccagaaaaca cuccuuggua ugguaaaaua gauggguuua uaaaugaacu uaaaaaguua      840

gcucuuuaug gaaaaauaaa ugauaauaac ucuuggauaa uagauaacgg uauauaucau      900

auagcaccuu uagggaaguu acauagcaau aauaaaauag gaauagaaac uuuaacagag      960

guuaugaaag uuuauccuua uuuaaguaug caacauuuac aaucagcaga ucaaauuaag     1020

cgucauuaug auucaaaaga ugcugaagga aacaaaauac cuuuagauaa guuuaaaaag     1080

gaaggaaaag aaaaauacug uccaaaaacu uauacauuug augauggaaa aguaauaaua     1140

aaagcuggug cuagaguaga agaagaaaaa guuaaaagac uauacugggc aucaaaggaa     1200

guuaacucuc aauucuuuag aguauacgga auagacaaac cauuagaaga agguaaucca     1260

gaugauauau uaacaauggu uaucuacaac agucccgaag aauauaaacu caauaguguu     1320

cuauacggau augauacuaa uaaugguggu auguauauag agccagaagg aacuuucuuc     1380

accuaugaaa gagaagcuca agaaagcaca uacacauuag aagaauuauu uagacaugaa     1440

uauacacauu auuugcaagg aagauaugca guuccaggac aauggggaag aacaaaacuu     1500

uaugacaaug auagauuaac uugguaugaa gaagguggag cagaauuauu ugcagguucu     1560

acuagaacuu cuggaauauu accaagaaag aguauaguau caaauauuca uaauacaaca     1620

agaaauaaua gauauaagcu uucagacacu guacauucua aauauggugc uaguuuugaa     1680

uucuauaauu augcauguau guuuauggau uauauguaua auaaagauau ggguauauua     1740

aauaaacuaa augaucuugc aaaaaauaau gauguugaug gauaugauaa uuauauuaga     1800

gauuuaaguu cuaauuaugc uuuaaaugau aaauaucaag aucauaugca ggagcgcaua     1860

gauaauuaug aaaauuuaac agugccuuuu guagcugaug auuauuuagu aaggcaugcu     1920

uauaagaacc cuaaugaaau uuauucugaa auaucugaag uagcaaaauu aaaggaugcu     1980

aagagugaag uuaagaaauc acaauauuuu aguaccuuua cuuugagagg uaguuacaca     2040

gguggagcau cuaaggggaa auuagaagau caaaaagcaa ugaauaaguu uauagaugau     2100

ucacuuaaga aauuagauac guauucuugg aguggguaua aaacuuuaac ugcuuauuuc     2160

acuaauuaua aaguugacuc uucaaauaga guuacuuaug auguaguauu ccacggauau     2220

uuaccaaacg aaggugauuc caaaaauuca uuaccuuaug gcaagaucaa uggaacuuac     2280

aagggaacag agaaagaaaa aaucaaauuc ucuagugaag gcucuuucga uccagauggu     2340

aaaauaguuu cuuaugaaug ggauuucgga gaugguaaua agaguaauga ggaaaaucca     2400

gagcauucau augacaaggu aggaacuuau acagugaaau uaaaaguuac ugaugacaag     2460

ggagaaucuu caguaucuac uacuacugca gaaauaaagg aucuuucaga aaauaaacuu     2520

ccaguuauau auaugcaugu accuaaaucc ggagccuuaa aucaaaaagu uguuuucuau     2580

ggaaaaggaa cauaugaccc agauggaucu aucgcaggau aucaauggga cuuuggugau     2640

ggaagugauu uuagcaguga acaaaaccca agccauguau auacuaaaaa aggugaauau     2700

acuguaacau uaagaguaau ggauaguagu ggacaaauga gugaaaaaac uaugaagauu     2760

aagauuacag auccgguaua uccaauaggc acugaaaaag aaccaaauaa caguaaagaa     2820

acugcaagug guccaauagu accagguaua ccuguuagug gaaccauaga aaauacaagu     2880

gaucaagauu auuucuauuu ugauguuaua acaccaggag aaguaaaaau agauauaaau     2940

aaauuagggu acggaggagc uacuugggua guauaugaug aaaauaauaa ugcaguaucu     3000

uaugccacug augaugggca aaauuuaagu ggaaaguuua aggcagauaa accagguaga     3060

uauuacaucc aucuuuacau guuuaauggu aguuauaugc cauauagaau uaauauagaa     3120

gguucaguag gaagauaa                                                   3138


<210>  122
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  122
augaaguggg uaaccuuuau uucccuucuu uuucucuuua gcucggcuua uuccaugaaa       60

aggaaauguu uaucuaaaag gcuuauguua gcuauaacaa uggcuacaau auuuacagug      120

aacaguacau uaccaauuua ugcagcugua gauaaaaaua augcaacagc agcuagaagg      180

cggcgcaaga gaguacaaaa ugaaaguaag agguauacag uaucauauuu aaagacuuua      240

aauuauuaug acuuaguaga uuugcuuguu aagacugaaa uugagaauuu accagaccuu      300

uuucaguaua guucagaugc aaaagaguuc uauggaaaua aaacucguau gagcuuuauc      360

auggaugaaa uugguagaag ggcaccucag uauacagaga uagaucauaa agguauuccu      420

acuuuaguag aaguuguaag agcuggauuu uacuuaggau uccauaacaa ggaauugaau      480

gaaauaaaca agaggucuuu uaaagaaagg guaauaccuu cuauauuagc aauucaaaaa      540

aauccuaauu uuaaacuagg uacugaaguu caagauaaaa uaguaucugc aacaggacuu      600

uuagcuggua augaaacagc gccuccagaa guuguaaaua auuuuacacc aauacuucaa      660

gacuguauaa agaauauaga cagauacgcu cuugaugauu uaaagucaaa agcauuauuu      720

aauguuuuag cugcaccuac cuaugauaua acugaguauu uaagagcuac uaaagaaaaa      780

ccagaaaaca cuccuuggua ugguaaaaua gauggguuua uaaaugaacu uaaaaaguua      840

gcucuuuaug gaaaaauaaa ugauaauaac ucuuggauaa uagauaacgg uauauaucau      900

auagcaccuu uagggaaguu acauagcaau aauaaaauag gaauagaaac uuuaacagag      960

guuaugaaag uuuauccuua uuuaaguaug caacauuuac aaucagcaga ucaaauuaag     1020

cgucauuaug auucaaaaga ugcugaagga aacaaaauac cuuuagauaa guuuaaaaag     1080

gaaggaaaag aaaaauacug uccaaaaacu uauacauuug augauggaaa aguaauaaua     1140

aaagcuggug cuagaguaga agaagaaaaa guuaaaagac uauacugggc aucaaaggaa     1200

guuaacucuc aauucuuuag aguauacgga auagacaaac cauuagaaga agguaaucca     1260

gaugauauau uaacaauggu uaucuacaac agucccgaag aauauaaacu caauaguguu     1320

cuauacggau augauacuaa uaaugguggu auguauauag agccagaagg aacuuucuuc     1380

accuaugaaa gagaagcuca agaaagcaca uacacauuag aagaauuauu uagacaugaa     1440

uauacacauu auuugcaagg aagauaugca guuccaggac aauggggaag aacaaaacuu     1500

uaugacaaug auagauuaac uugguaugaa gaagguggag cagaauuauu ugcagguucu     1560

acuagaacuu cuggaauauu accaagaaag aguauaguau caaauauuca uaauacaaca     1620

agaaauaaua gauauaagcu gucagacacu guacauucua aauauggugc uaguuuugag     1680

uucuauaauu augcauguau guuuauggau uauauguaua auaaagauau ggguauauua     1740

aauaaacuaa augaucuugc aaaaaauaau gauguugaug gauaugauaa uuauauuaga     1800

gauuuaaguu cuaauuaugc uuuaaaugau aaauaucaag aucauaugca ggagcgcaua     1860

gauaauuaug aaaauuuaac agugccuuuu guagcugaug auuauuuagu aaggcaugcu     1920

uauaagaacc cuaaugaaau uuauucugaa auaucugaag uagcaaaauu aaaggaugcu     1980

aagagugaag uuaagaaauc acaauauuuu aguaccuuua cuuugagagg uaguuacaca     2040

gguggagcau cuaaggggaa auuagaagau caaaaagcaa ugaauaaguu uauagaugau     2100

ucacuuaaga aauuagauac guauucuugg aguggguaua aaacuuuaac ugcuuauuuc     2160

acuaauuaua aaguugacuc uucaaauaga guuacuuaug auguaguauu ccacggauau     2220

uuaccaaacg aaggugauuc caaaaauuca uuaccuuaug gcaagaucaa uggaacuuac     2280

aagggaacag agaaagaaaa aaucaaauuc ucuagugaag gcucuuucga uccagauggu     2340

aaaauaguuu cuuaugaaug ggauuucgga gaugguaaua agaguaauga ggaaaaucca     2400

gagcauucau augacaaggu aggaacuuau acagugaaau uaaaaguuac ugaugacaag     2460

ggagaaucuu caguaucuac uacuacugca gaaauaaagg aucuuucaga aaauaaacuu     2520

ccaguuauau auaugcaugu accuaaaucc ggagccuuaa aucaaaaagu uguuuucuau     2580

ggaaaaggaa cauaugaccc agauggaucu aucgcaggau aucaauggga cuuuggugau     2640

ggaagugauu uuagcaguga acaaaaccca agccauguau auacuaaaaa aggugaauau     2700

acuguaacau uaagaguaau ggauaguagu ggacaaauga gugaaaaaac uaugaagauu     2760

aagauuacag auccgguaua uccaauaggc acugaaaaag aaccaaauaa caguaaagaa     2820

acugcaagug guccaauagu accagguaua ccuguuagug gaaccauaga aaauacaagu     2880

gaucaagauu auuucuauuu ugauguuaua acaccaggag aaguaaaaau agauauaaau     2940

aaauuagggu acggaggagc uacuugggua guauaugaug aaaauaauaa ugcaguaucu     3000

uaugccacug augaugggca aaauuuaagu ggaaaguuua aggcagauaa accagguaga     3060

uauuacaucc aucuuuacau guuuaauggu aguuauaugc cauauagaau uaauauagaa     3120

gguucaguag gaagauaa                                                   3138


<210>  123
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  123
auggggaccu ggauuuuauu ugccugccuc cugggagcag cuuuugccau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggugcuuac cccuuugaag      120

ugguaccaga gcauaaggcc accguacccu uccuaugguu acgagcccau ggguggaugg      180

cugcaccacc aaaucauccc cgugcugucc caacagcacc ccccgacuca cacccugcag      240

ccucaucacc acaucccagu ggugccagcu cagcagcccg ugauccccca gcaaccaaug      300

augcccguuc cuggccaaca cuccaugacu ccaauccaac accaccagcc aaaccucccu      360

ccgcccgccc agcagcccua ccagccccag ccuguucagc cacagccuca ccagcccaug      420

cagccccagc caccugugca ccccaugcag ccccugccgc cacagccacc ucugccuccg      480

auguucccca ugcagccccu gccucccaug cuuccugauc ugacucugga agcuuggcca      540

ucaacagaca agaccaagcg ggaggaagug gauuaa                                576


<210>  124
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  124
auggggaccu ggauuuuauu ugccugccuc cugggagcag cuuuugccau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggugcuuac cccuuugaag      120

ugguaccaga gcauaaggcc accguacccu uccuaugguu acgagcccau ggguggaugg      180

cugcaccacc aaaucauccc cgugcugucc caacagcacc ccccgacuca cacccugcag      240

ccucaucacc acaucccagu ggugccagcu cagcagcccg ugauccccca gcaaccaaug      300

augcccguuc cuggccaaca cuccaugacu ccaauccaac accaccagcc aaaccucccu      360

ccgcccgccc agcagcccua ccagccccag ccuguucagc cacagccuca ccagcccaug      420

cagccccagc caccugugca ccccaugcag ccccugccgc cacagccacc ucugccuccg      480

auguucccca ugcagccccu gccucccaug cuuccugauc ugacucugga agcauggcca      540

ucaacagaca agaccaagcg ggaggaagug gauuaa                                576


<210>  125
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  125
augccucuac caccucaucc ugggcacccu gguuauauca acuucagcua ugaggugcuu       60

accccuuuga agugguacca gagcauaagg ccaccguacc cuuccuaugg uuacgagccc      120

auggguggau gguaa                                                       135


<210>  126
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  126
augccucuac caccucaucc ugggcacccu gguuauauca acuucagcua ugaggugcuu       60

accccuuuga agugguacca gagcauaagg ccaccuccca ugcuuccuga ucugacucug      120

gaagcuuggc caucaacaga caagaccaag cgggaggaag uggauuaa                   168


<210>  127
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  127
augccucuac caccucaucc ugggcacccu gguuauauca acuucagcua ugaggugcuu       60

accccuuuga agugguacca gagcauaagg ccaccuccca ugcuuccuga ucugacucug      120

gaagcauggc caucaacaga caagaccaag cgggaggaag uggauuaa                   168


<210>  128
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  128
auggccguca uggcgccccg aacccucguc cugcuacucu cgggggcucu ggcccugacc       60

cagaccuggg cgaugccucu accaccucau ccugggcacc cugguuauau caacuucagc      120

uaugaggugc uuaccccuuu gaagugguac cagagcauaa ggccaccgua cccuuccuau      180

gguuacgagc ccaugggugg augguaa                                          207


<210>  129
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  129
auggccguca uggcgccccg aacccucguc cugcuacucu cgggggcucu ggcccugacc       60

cagaccuggg cgaugccucu accaccucau ccugggcacc cugguuauau caacuucagc      120

uaugaggugc uuaccccuuu gaagugguac cagagcauaa ggccaccucc caugcuuccu      180

gaucugacuc uggaagcaug gccaucaaca gacaagacca agcgggagga aguggauuaa      240


<210>  130
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  130
auggggaccu ggauuuuguu ugccugccuu gugggagcag cuuuugccau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggugcucac cccuuugaag      120

ugguaccaga gcaugauaag accaccauac ucuuccuaug guuacgagcc caugggugga      180

uggcugcacc accaaaucau ccccguggug ucccaacagc acccccugac ucacacccug      240

cagucucauc accacauccc aguggugcca gcucagcagc ccaggguccg ccagcaagca      300

cugaugccug uuccuggcca gcaauccaug acuccaaccc aacaccauca gccaaaccuc      360

ccucugccug cccagcagcc cuuccagccc cagccuguuc agccacagcc ucaccagccc      420

augcagcccc agccaccugu gcaacccaug cagccccugc ugccacagcc accucugccu      480

ccaauguucc cccugcggcc ccugcccccc auacuuccug aucugcaucu ggaagcuugg      540

ccagcaacag acaagaccaa gcaggaggaa guggauuaa                             579


<210>  131
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  131
auggggaccu ggauuuuguu ugccugccuu gugggagcag cuuuugccau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggugcucac cccuuugaag      120

ugguaccaga gcaugauaag accaccauac ucuuccuaug guuacgagcc caugggugga      180

uggcugcacc accaaaucau ccccguggug ucccaacagc acccccugac ucacacccug      240

cagucucauc accacauccc aguggugcca gcucagcagc ccaggguccg ccagcaagca      300

cugaugccug uuccuggcca gcaauccaug acuccaaccc aacaccauca gccaaaccuc      360

ccucugccug cccagcagcc cuuccagccc cagccuguuc agccacagcc ucaccagccc      420

augcagcccc agccaccugu gcaacccaug cagccccugc ugccacagcc accucugccu      480

ccaauguucc cccugcggcc ccugcccccc auacuuccug aucugcaucu ggaagcaugg      540

ccagcaacag acaagaccaa gcaggaggaa guggauuaa                             579


<210>  132
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  132
augccucuac caccucaucc ugggcacccu gguuauauca acuucagcua ugaggugcuc       60

accccuuuga agugguacca gagcaugaua agaccaccau acucuuccua ugguuacgag      120

cccaugggug gaugguaa                                                    138


<210>  133
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  133
augccucuac caccucaucc ugggcacccu gguuauauca acuucagcua ugaggugcuc       60

accccuuuga agugguacca gagcaugaua agaccacccc ccauacuucc ugaucugcau      120

cuggaagcuu ggccagcaac agacaagacc aagcaggagg aaguggauua a               171


<210>  134
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  134
augccucuac caccucaucc ugggcacccu gguuauauca acuucagcua ugaggugcuc       60

accccuuuga agugguacca gagcaugaua agaccacccc ccauacuucc ugaucugcau      120

cuggaagcau ggccagcaac agacaagacc aagcaggagg aaguggauua a               171


<210>  135
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  135
auggccguca uggcgccccg aacccucguc cugcuacucu cgggggcucu ggcccugacc       60

cagaccuggg cgaugccucu accaccucau ccugggcacc cugguuauau caacuucagc      120

uaugaggugc ucaccccuuu gaagugguac cagagcauga uaagaccacc auacucuucc      180

uaugguuacg agcccauggg uggaugguaa                                       210


<210>  136
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  136
auggccguca uggcgccccg aacccucguc cugcuacucu cgggggcucu ggcccugacc       60

cagaccuggg cgaugccucu accaccucau ccugggcacc cugguuauau caacuucagc      120

uaugaggugc ucaccccuuu gaagugguac cagagcauga uaagaccacc ccccauacuu      180

ccugaucugc aucuggaagc auggccagca acagacaaga ccaagcagga ggaaguggau      240

uaa                                                                    243


<210>  137
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  137
auggggaccu ggauuuuguu ugcuugccuc cugggagcag ccuucucuau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggugcuuac cccucugaag      120

ugguaccaga acaugauaag acauccguac acuuccuaug gguacgaacc caugggugga      180

uggcugcacc accaaaucau acccguggug ucgcagcaga cuccccagag ucaugcccuu      240

cagccucauc accacauccc cauggugcca gcucaacagc ccgggauccc ccagcagcca      300

augaugccac uuccuggcca acacuccaug acuccaaccc aacaccacca gccaaaccuc      360

ccucugcccg cccagcagcc cuuccagccc cagcccgucc agccccagcc ucaccagccc      420

cugcagcccc agucacccau gcaccccauc cagcccuugc ugccacagcc accucugccu      480

ccgauguucu ccaugcaguc ucugcuuccu gaccugccuc uggaagcuug gccagcaaca      540

gacaagacca agcgggagga aguggauuaa                                       570


<210>  138
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  138
auggggaccu ggauuuuguu ugcuugccuc cugggagcag ccuucucuau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggugcuuac cccucugaag      120

ugguaccaga acaugauaag acauccguac acuuccuaug gguacgaacc caugggugga      180

uggcugcacc accaaaucau acccguggug ucgcagcaga cuccccagag ucaugcccuu      240

cagccucauc accacauccc cauggugcca gcucaacagc ccgggauccc ccagcagcca      300

augaugccac uuccuggcca acacuccaug acuccaaccc aacaccacca gccaaaccuc      360

ccucugcccg cccagcagcc cuuccagccc cagcccgucc agccccagcc ucaccagccc      420

cugcagcccc agucacccau gcaccccauc cagcccuugc ugccacagcc accucugccu      480

ccgauguucu ccaugcaguc ucugcuuccu gaccugccuc uggaagcaug gccagcaaca      540

gacaagacca agcgggagga aguggauuaa                                       570


<210>  139
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  139
augccucuac caccucaucc ugggcacccu gguuauauca acuucagcua ugaggugcuu       60

accccucuga agugguacca gaacaugaua agacauccgu acacuuccua uggguacgaa      120

cccaugggug gaugguaa                                                    138


<210>  140
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  140
augccucuac caccucaucc ugggcacccu gguuauauca acuucagcua ugaggugcuu       60

accccucuga agugguacca gaacaugaua agacauccgu cucugcuucc ugaccugccu      120

cuggaagcuu ggccagcaac agacaagacc aagcgggagg aaguggauua a               171


<210>  141
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  141
augccucuac caccucaucc ugggcacccu gguuauauca acuucagcua ugaggugcuu       60

accccucuga agugguacca gaacaugaua agacauccgu cucugcuucc ugaccugccu      120

cuggaagcau ggccagcaac agacaagacc aagcgggagg aaguggauua a               171


<210>  142
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  142
auggccguca uggcgccccg aacccucguc cugcuacucu cgggggcucu ggcccugacc       60

cagaccuggg cgaugccucu accaccucau ccugggcacc cugguuauau caacuucagc      120

uaugaggugc uuaccccucu gaagugguac cagaacauga uaagacaucc guacacuucc      180

uauggguacg aacccauggg uggaugguaa                                       210


<210>  143
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  143
auggccguca uggcgccccg aacccucguc cugcuacucu cgggggcucu ggcccugacc       60

cagaccuggg cgaugccucu accaccucau ccugggcacc cugguuauau caacuucagc      120

uaugaggugc uuaccccucu gaagugguac cagaacauga uaagacaucc gucucugcuu      180

ccugaccugc cucuggaagc auggccagca acagacaaga ccaagcggga ggaaguggau      240

uaa                                                                    243


<210>  144
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  144
auggggaccu ggauuuuguu ugcuugccuc cugggagcag ccuucucuau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaua uaagacaucc guacacuucc      120

uauggguacg aacccauggg uggauggcug caccaccaaa ucauacccgu ggugucgcag      180

cagacucccc agagucaugc ccuucagccu caucaccaca uccccauggu gccagcucaa      240

cagcccggga ucccccagca gccaaugaug ccacuuccug gccaacacuc caugacucca      300

acccaacacc accagccaaa ccucccucug cccgcccagc agcccuucca gccccagccc      360

guccagcccc agccucacca gccccugcag ccccagucac ccaugcaccc cauccagccc      420

uugcugccac agccaccucu gccuccgaug uucuccaugc agucucugcu uccugaccug      480

ccucuggaag cuuggccagc aacagacaag accaagcggg aggaagugga uuaa            534


<210>  145
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  145
auggggaccu ggauuuucuu ugccugccuu uugggagcau cccuugcuau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggugcuuac cccucugaag      120

ugguaccaga acaugauaag acauccguac acuuccuaug gguacgaacc caugggugga      180

uggcugcacc accaaaucau acccguggug ucgcagcaga cuccccagag ucaugcccuu      240

cagccucauc accacauccc cauggugcca gcucaacagc ccgggauccc ccagcagcca      300

augaugccac uuccuggcca acacuccaug acuccaaccc aacaccacca gccaaaccuc      360

ccucugcccg cccagcagcc cuuccagccc cagcccgucc agccccagcc ucaccagccc      420

cugcagcccc agucacccau gcaccccauc cagcccuugc ugccacagcc accucugccu      480

ccgauguucu ccaugcaguc ucugcuuccu gaccugccuc uggaagcuug gccagcaaca      540

gacaagacca agcgggagga aguggauuaa                                       570


<210>  146
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  146
auggggaccu ggauuuuguu ugcuugccuc cugggagcag ccuucucuau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggugcuuac cccucugaag      120

ugguaccaga acaugauaag acauccgucu cugcuuccug accugccucu ggaagcuugg      180

ccagcaacag acaagaccaa gcgggaggaa guggauuaa                             219


<210>  147
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  147
auggggaccu ggauuuuguu ugcuugccuc cugggagcag ccuucucuau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggacuuaua cuuggaggcu      120

auccguauug acaggacugc auucgugcuu accccucuga agugguacca gaacaugaua      180

agacauccgu acacuuccua ugguuacgaa cccaugggug gauggcugca ccaccaaauc      240

auucccgugg ugucgcagca gacuccccag agucaugccc uucagccuca ucaccacauc      300

cccauggugc cagcucaaca gcccgggauc ccccagcagc caaugaugcc acuuccuggc      360

caacacucca ugacuccaac ccaacaccac cagccaaacc ucccucugcc cgcccagcag      420

cccuuccagc cccagcccgu ccagccccag ccucaccagc cccugcagcc ccagucaccc      480

augcacccca uccagcccuu gcugccacag ccaccucugc cuccgauguu cuccaugcag      540

ucucugcuuc cugaccugcc ucuggaagcu uggccagcaa cagacaagac caagcgggag      600

gaaguggauu aa                                                          612


<210>  148
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  148
auggggaccu ggauuuuguu ugcuugccuc cugggagcag ccuucucuau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggugcuuac cccucugaag      120

ugguaccaga acaugauaag acauccgacu ccccagaguc augcccuuca gccucaucac      180

cacaucccca uggugccagc ucaacagccc gggauccccc agcagccaau gaugccacuu      240

ccuggccaac acuccaugac uccaacccaa caccaccagc caaaccuccc ucugcccgcc      300

cagcagcccu uccagcccca gcccguccag ccccagccuc accagccccu gcagccccag      360

ucacccaugc accccaucca gcccuugcug ccacagccac cucugccucc gauguucucc      420

augcagucuc ugcuuccuga ccugccucug gaagcuuggc cagcaacaga caagaccaag      480

cgggaggaag uggauuaa                                                    498


<210>  149
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  149
augccucuac caccucaucc ugggcacccu gguuauauca acuucagcua ugaggugcuu       60

accccucuga agugguacca gaacaugaua agacauccgu acacuuccua uggguacgaa      120

cccaugggug gauggcugca ccaccaaauc auacccgugg ugucgcagca gacuccccag      180

agucaugccc uucagccuca ucaccacauc cccauggugc cagcucaaca gcccgggauc      240

ccccagcagc caaugaugcc acuuccuggc caacacucca ugacuccaac ccaacaccac      300

cagccaaacc ucccucugcc cgcccagcag cccuuccagc cccagcccgu ccagccccag      360

ccucaccagc cccugcagcc ccagucaccc augcacccca uccagcccuu gcugccacag      420

ccaccucugc cuccgauguu cuccaugcag ucucugcuuc cugaccugcc ucuggaagcu      480

uggccagcaa cagacaagac caagcgggag gaaguggauu aa                         522


<210>  150
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  150
augcccggcg uggcccgccu gccgcugcug cucgggcugc ugcugcuccc gcgucccggc       60

cggccgcugg acuuggccga cuacaccuau gaccuggcgg aggaggacga cucggagccc      120

cucaacuaca aagaccccug caaggcggcu gccuuucuug gggacauugc ccuggacgaa      180

gaggaccuga gggccuucca gguacagcag gcuguggauc ucagacggca cacagcucgu      240

aaguccucca ucaaagcugc aguuccagga aacacuucua cccccagcug ccagagcacc      300

aacgggcagc cucagagggg agccuguggg agauggagag guagaucccg uagccggcgg      360

gcggcgacgu cccgaccaga gcgugugugg cccgaugggg ucauccccuu ugucauuggg      420

ggaaacuuca cugguagcca gagggcaguc uuccggcagg ccaugaggca cugggagaag      480

cacaccugug ucaccuuccu ggagcgcacu gacgaggaca gcuauauugu guucaccuau      540

cgaccuugcg ggugcugcuc cuacgugggu cgccgcggcg ggggccccca ggccaucucc      600

aucggcaaga acugugacaa guucggcauu gugguccacg agcugggcca cgucgucggc      660

uucuggcacg aacacacucg gccagaccgg gaccgccacg uuuccaucgu ucgugagaac      720

auccagccag ggcaggagua uaacuuccug aagauggagc cucaggaggu ggagucccug      780

ggggagaccu augacuucga cagcaucaug cauuacgcuc ggaacacauu cuccaggggc      840

aucuuccugg auaccauugu ccccaaguau gaggugaacg gggugaaacc ucccauuggc      900

caaaggacac ggcucagcaa gggggacauu gcccaagccc gcaagcuuua caagugccca      960

gccuguggag agacccugca agacagcaca ggcaacuucu ccuccccuga auaccccaau     1020

ggcuacucug cucacaugca cugcgugugg cgcaucucug ucacacccgg ggagaagauc     1080

auccugaacu ucacgucccu ggaccuguac cgcagccgcc ugugcuggua cgacuaugug     1140

gagguccgag auggcuucug gaggaaggcg ccccuccgag gccgcuucug cggguccaaa     1200

cucccugagc cuaucgucuc cacugacagc cgccucuggg uugaauuccg cagcagcagc     1260

aauuggguug gaaagggcuu cuuugcaguc uacgaagcca ucugcggggg ugaugugaaa     1320

aaggacuaug gccacauuca aucgcccaac uacccagacg auuaccggcc cagcaaaguc     1380

ugcaucuggc ggauccaggu gucugagggc uuccacgugg gccucacauu ccaguccuuu     1440

gagauugagc gccacgacag cugugccuac gacuaucugg aggugcgcga cgggcacagu     1500

gagagcagca cccucaucgg gcgcuacugu ggcuaugaga agccugauga caucaagagc     1560

acguccagcc gccucuggcu caaguucguc ucugacgggu ccauuaacaa agcgggcuuu     1620

gccgucaacu uuuucaaaga gguggacgag ugcucucggc ccaaccgcgg gggcugugag     1680

cagcggugcc ucaacacccu gggcagcuac aagugcagcu gugaccccgg guacgagcug     1740

gccccagaca agcgccgcug ugaggcugcu uguggcggau uccucaccaa gcucaacggc     1800

uccaucacca gcccgggcug gcccaaggag uaccccccca acaagaacug caucuggcag     1860

cugguggccc ccacccagua ccgcaucucc cugcaguuug acuucuuuga gacagagggc     1920

aaugaugugu gcaaguacga cuucguggag gugcgcagug gacucacagc ugacuccaag     1980

cugcauggca aguucugugg uucugagaag cccgagguca ucaccuccca guacaacaac     2040

augcgcgugg aguucaaguc cgacaacacc guguccaaaa agggcuucaa ggcccacuuc     2100

uucucagaca aggacgagug cuccaaggau aacggcggcu gccagcagga cugcgucaac     2160

acguucggca guuaugagug ccaaugccgc aguggcuucg uccuccauga caacaagcac     2220

gacugcaaag aagccggcug ugaccacaag gugacaucca ccagugguac caucaccagc     2280

cccaacuggc cugacaagua ucccagcaag aaggagugca cgugggccau cuccagcacc     2340

cccgggcacc gggucaagcu gaccuucaug gagauggaca ucgaguccca gccugagugu     2400

gccuacgacc accuagaggu guucgacggg cgagacgcca aggcccccgu ccucggccgc     2460

uucuguggga gcaagaagcc cgagcccguc cuggccacag gcagccgcau guuccugcgc     2520

uucuacucag auaacucggu ccagcgaaag ggcuuccagg ccucccacgc cacagagugc     2580

gggggccagg uacgggcaga cgugaagacc aaggaccuuu acucccacgc ccaguuuggc     2640

gacaacaacu acccuggggg uguggacugu gaguggguca uuguggccga ggaaggcuac     2700

ggcguggagc ucguguucca gaccuuugag guggaggagg agaccgacug cggcuaugac     2760

uacauggagc ucuucgacgg cuacgacagc acagccccca ggcuggggcg cuacuguggc     2820

ucagggccuc cugaggaggu guacucggcg ggagauucug uccuggugaa guuccacucg     2880

gaugacacca ucaccaaaaa agguuuccac cugcgauaca ccagcaccaa guuccaggac     2940

acacuccaca gcaggaagug a                                               2961


<210>  151
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  151
augguggccg ggacccgcug ucuucuagcg uugcugcuuc cccagguccu ccugggcggc       60

gcggcuggcc ucguuccgga gcugggccgc aggaaguucg cggcggcguc gucgggccgc      120

cccucauccc agcccucuga cgagguccug agcgaguucg aguugcggcu gcucagcaug      180

uucggccuga aacagagacc cacccccagc agggacgccg uggugccccc cuacaugcua      240

gaccuguauc gcaggcacuc aggucagccg ggcucacccg ccccagacca ccgguuggag      300

agggcagcca gccgagccaa cacugugcgc agcuuccacc augaagaauc uuuggaagaa      360

cuaccagaaa cgagugggaa aacaacccgg agauucuucu uuaauuuaag uucuaucccc      420

acggaggagu uuaucaccuc agcagagcuu cagguuuucc gagaacagau gcaagaugcu      480

uuaggaaaca auagcaguuu ccaucaccga auuaauauuu augaaaucau aaaaccugca      540

acagccaacu cgaaauuccc cgugaccaga cuuuuggaca ccagguuggu gaaucagaau      600

gcaagcaggu gggaaaguuu ugaugucacc cccgcuguga ugcgguggac ugcacaggga      660

cacgccaacc auggauucgu gguggaagug gcccacuugg aggagaaaca aggugucucc      720

aagagacaug uuaggauaag caggucuuug caccaagaug aacacagcug gucacagaua      780

aggccauugc uaguaacuuu uggccaugau ggaaaagggc auccucucca caaaagagaa      840

aaacgucaag ccaaacacaa acagcggaaa cgccuuaagu ccagcuguaa gagacacccu      900

uuguacgugg acuucaguga cguggggugg aaugacugga uuguggcucc cccgggguau      960

cacgccuuuu acugccacgg agaaugcccu uuuccucugg cugaucaucu gaacuccacu     1020

aaucaugcca uuguucagac guuggucaac ucuguuaacu cuaagauucc uaaggcaugc     1080

ugugucccga cagaacucag ugcuaucucg augcuguacc uugacgagaa ugaaaagguu     1140

guauuaaaga acuaucagga caugguugug gaggguugug ggugucgcua g              1191


<210>  152
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  152
augauuccug guaaccgaau gcugaugguc guuuuauuau gccaaguccu gcuaggaggc       60

gcgagccaug cuaguuugau accugagacg gggaagaaaa aagucgccga gauucagggc      120

cacgcgggag gacgccgcuc agggcagagc caugagcucc ugcgggacuu cgaggcgaca      180

cuucugcaga uguuugggcu gcgccgccgc ccgcagccua gcaagagugc cgucauuccg      240

gacuacaugc gggaucuuua ccggcuucag ucuggggagg aggaggaaga gcagauccac      300

agcacugguc uugaguaucc ugagcgcccg gccagccggg ccaacaccgu gaggagcuuc      360

caccacgaag aacaucugga gaacauccca gggaccagug aaaacucugc uuuucguuuc      420

cucuuuaacc ucagcagcau cccugagaac gaggugaucu ccucugcaga gcuucggcuc      480

uuccgggagc agguggacca gggcccugau ugggaaaggg gcuuccaccg uauaaacauu      540

uaugagguua ugaagccccc agcagaagug gugccugggc accucaucac acgacuacug      600

gacacgagac ugguccacca caaugugaca cggugggaaa cuuuugaugu gagcccugcg      660

guccuucgcu ggacccggga gaagcagcca aacuaugggc uagccauuga ggugacucac      720

cuccaucaga cucggaccca ccagggccag caugucagga uuagccgauc guuaccucaa      780

gggaguggga auugggccca gcuccggccc cuccugguca ccuuuggcca ugauggccgg      840

ggccaugccu ugacccgacg ccggagggcc aagcguagcc cuaagcauca cucacagcgg      900

gccaggaaga agaauaagaa cugccggcgc cacucgcucu auguggacuu cagcgaugug      960

ggcuggaaug acuggauugu ggccccacca ggcuaccagg ccuucuacug ccauggggac     1020

ugccccuuuc cacuggcuga ccaccucaac ucaaccaacc augccauugu gcagacccug     1080

gucaauucug ucaauuccag uauccccaaa gccuguugug ugcccacuga acugagugcc     1140

aucuccaugc uguaccugga ugaguaugau aaggugguac ugaaaaauua ucaggagaug     1200

guaguagagg gaugugggug ccgcuga                                         1227


<210>  153
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  153
augccggggc uggggcggag ggcgcagugg cugugcuggu ggugggggcu gcugugcagc       60

ugcugcgggc ccccgccgcu gcggccgccc uugcccgcug ccgcggccgc cgccgccggg      120

gggcagcugc ugggggacgg cgggagcccc ggccgcacgg agcagccgcc gccgucgccg      180

caguccuccu cgggcuuccu guaccggcgg cucaagacgc aggagaagcg ggagaugcag      240

aaggagaucu ugucggugcu ggggcucccg caccggcccc ggccccugca cggccuccaa      300

cagccgcagc ccccggcgcu ccggcagcag gaggagcagc agcagcagca gcagcugccu      360

cgcggagagc ccccucccgg gcgacugaag uccgcgcccc ucuucaugcu ggaucuguac      420

aacgcccugu ccgccgacaa cgacgaggac ggggcgucgg agggggagag gcagcagucc      480

uggccccacg aagcagccag cucgucccag cgucggcagc cgcccccggg cgccgcgcac      540

ccgcucaacc gcaagagccu ucuggccccc ggaucuggca gcggcggcgc guccccacug      600

accagcgcgc aggacagcgc cuuccucaac gacgcggaca uggucaugag cuuugugaac      660

cugguggagu acgacaagga guucuccccu cgucagcgac accacaaaga guucaaguuc      720

aacuuauccc agauuccuga gggugaggug gugacggcug cagaauuccg caucuacaag      780

gacuguguua uggggaguuu uaaaaaccaa acuuuucuua ucagcauuua ucaagucuua      840

caggagcauc agcacagaga cucugaccug uuuuuguugg acacccgugu aguaugggcc      900

ucagaagaag gcuggcugga auuugacauc acggccacua gcaaucugug gguugugacu      960

ccacagcaua acauggggcu ucagcugagc guggugacaa gggauggagu ccacguccac     1020

ccccgagccg caggccuggu gggcagagac ggcccuuacg acaagcagcc cuucauggug     1080

gcuuucuuca aagugaguga ggugcacgug cgcaccacca ggucagccuc cagccggcgc     1140

cgacaacaga gucguaaucg cucuacccag ucccaggacg uggcgcgggu cuccagugcu     1200

ucagauuaca acagcaguga auugaaaaca gccugcagga agcaugagcu guaugugagu     1260

uuccaagacc ugggauggca ggacuggauc auugcaccca agggcuaugc ugccaauuac     1320

ugugauggag aaugcuccuu cccacucaac gcacacauga augcaaccaa ccacgcgauu     1380

gugcagaccu ugguucaccu uaugaacccc gaguaugucc ccaaaccgug cugugcgcca     1440

acuaagcuaa augccaucuc gguucuuuac uuugaugaca acuccaaugu cauucugaaa     1500

aaauacagga auaugguugu aagagcuugu ggaugccacu aa                        1542


<210>  154
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  154
augcacgugc gcucacugcg agcugcggcg ccgcacagcu ucguggcgcu cugggcaccc       60

cuguuccugc ugcgcuccgc ccuggccgac uucagccugg acaacgaggu gcacucgagc      120

uucauccacc ggcgccuccg cagccaggag cggcgggaga ugcagcgcga gauccucucc      180

auuuugggcu ugccccaccg cccgcgcccg caccuccagg gcaagcacaa cucggcaccc      240

auguucaugc uggaccugua caacgccaug gcgguggagg agggcggcgg gcccggcggc      300

cagggcuucu ccuaccccua caaggccguc uucaguaccc agggcccccc ucuggccagc      360

cugcaagaua gccauuuccu caccgacgcc gacaugguca ugagcuucgu caaccucgug      420

gaacaugaca aggaauucuu ccacccacgc uaccaccauc gagaguuccg guuugaucuu      480

uccaagaucc cagaagggga agcugucacg gcagccgaau uccggaucua caaggacuac      540

auccgggaac gcuucgacaa ugagacguuc cggaucagcg uuuaucaggu gcuccaggag      600

cacuugggca gggaaucgga ucucuuccug cucgacagcc guacccucug ggccucggag      660

gagggcuggc ugguguuuga caucacagcc accagcaacc acuggguggu caauccgcgg      720

cacaaccugg gccugcagcu cucgguggag acgcuggaug ggcagagcau caaccccaag      780

uuggcgggcc ugauugggcg gcacgggccc cagaacaagc agcccuucau gguggcuuuc      840

uucaaggcca cggaggucca cuuccgcagc auccggucca cggggagcaa acagcgcagc      900

cagaaccgcu ccaagacgcc caagaaccag gaagcccugc ggauggccaa cguggcagag      960

aacagcagca gcgaccagag gcaggccugu aagaagcacg agcuguaugu cagcuuccga     1020

gaccugggcu ggcaggacug gaucaucgcg ccugaaggcu acgccgccua cuacugugag     1080

ggggagugug ccuucccucu gaacuccuac augaacgcca ccaaccacgc caucgugcag     1140

acgcuggucc acuucaucaa cccggaaacg gugcccaagc ccugcugugc gcccacgcag     1200

cucaaugcca ucuccguccu cuacuucgau gacagcucca acgucauccu gaagaaauac     1260

agaaacaugg ugguccgggc cuguggcugc cacuag                               1296


<210>  155
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  155
augaaagccu cugcagcacu ucugugucug cugcucacag cagcugcuuu cagcccccag       60

gggcuugcuc agccaguugg gauuaauacu ucaacuaccu gcugcuacag auuuaucaau      120

aagaaaaucc cuaagcagag gcuggagagc uacagaagga ccaccaguag ccacuguccc      180

cgggaagcug uaaucuucaa gaccaaacug gacaaggaga ucugugcuga ccccacacag      240

aagugggucc aggacuuuau gaagcaccug gacaagaaaa cccaaacucc aaagcuuuga      300


<210>  156
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  156
augcugcuca cucuuaucau ucuguugcca guaguuucaa aauuuaguuu uguuagucuc       60

ucagcaccgc agcacuggag cuguccugaa gguacucucg caggaaaugg gaauucuacu      120

uguguggguc cugcacccuu cuuaauuuuc ucccauggaa auaguaucuu uaggauugac      180

acagaaggaa ccaauuauga gcaauuggug guggaugcug gugucucagu gaucauggau      240

uuucauuaua augagaaaag aaucuauugg guggauuuag aaagacaacu uuugcaaaga      300

guuuuucuga augggucaag gcaagagaga guauguaaua uagagaaaaa uguuucugga      360

auggcaauaa auuggauaaa ugaagaaguu auuuggucaa aucaacagga aggaaucauu      420

acaguaacag auaugaaagg aaauaauucc cacauucuuu uaagugcuuu aaaauauccu      480

gcaaauguag caguugaucc aguagaaagg uuuauauuuu ggucuucaga gguggcugga      540

agccuuuaua gagcagaucu cgauggugug ggagugaagg cucuguugga gacaucagag      600

aaaauaacag cugugucauu ggaugugcuu gauaagcggc uguuuuggau ucaguacaac      660

agagaaggaa gcaauucucu uauuugcucc ugugauuaug auggagguuc uguccacauu      720

aguaaacauc caacacagca uaauuuguuu gcaauguccc uuuuugguga ccguaucuuc      780

uauucaacau ggaaaaugaa gacaauuugg auagccaaca aacacacugg aaaggacaug      840

guuagaauua accuccauuc aucauuugua ccacuuggug aacugaaagu agugcaucca      900

cuugcacaac ccaaggcaga agaugacacu ugggagccug agcagaaacu uugcaaauug      960

aggaaaggaa acugcagcag cacugugugu gggcaagacc uccagucaca cuugugcaug     1020

ugugcagagg gauacgcccu aagucgagac cggaaguacu gugaagaugu uaaugaaugu     1080

gcuuuuugga aucauggcug uacucuuggg uguaaaaaca ccccuggauc cuauuacugc     1140

acgugcccug uaggauuugu ucugcuuccu gaugggaaac gaugucauca acuuguuucc     1200

uguccacgca augugucuga augcagccau gacuguguuc ugacaucaga aggucccuua     1260

uguuucuguc cugaaggcuc agugcuugag agagauggga aaacauguag cgguuguucc     1320

ucacccgaua augguggaug uagccagcuc ugcguuccuc uuagcccagu auccugggaa     1380

ugugauugcu uuccugggua ugaccuacaa cuggaugaaa aaagcugugc agcuucagga     1440

ccacaaccau uuuugcuguu ugccaauucu caagauauuc gacacaugca uuuugaugga     1500

acagacuaug gaacucugcu cagccagcag augggaaugg uuuaugcccu agaucaugac     1560

ccuguggaaa auaagauaua cuuugcccau acagcccuga aguggauaga gagagcuaau     1620

auggaugguu cccagcgaga aaggcuuauu gaggaaggag uagaugugcc agaaggucuu     1680

gcuguggacu ggauuggccg uagauucuau uggacagaca gagggaaauc ucugauugga     1740

aggagugauu uaaaugggaa acguuccaaa auaaucacua aggagaacau cucucaacca     1800

cgaggaauug cuguucaucc aauggccaag agauuauucu ggacugauac agggauuaau     1860

ccacgaauug aaaguucuuc ccuccaaggc cuuggccguc ugguuauagc cagcucugau     1920

cuaaucuggc ccaguggaau aacgauugac uucuuaacug acaaguugua cuggugcgau     1980

gccaagcagu cugugauuga aauggccaau cuggaugguu caaaacgccg aagacuuacc     2040

cagaaugaug uaggucaccc auuugcugua gcaguguuug aggauuaugu gugguucuca     2100

gauugggcua ugccaucagu aaugagagua aacaagagga cuggcaaaga uagaguacgu     2160

cuccaaggca gcaugcugaa gcccucauca cugguugugg uucauccauu ggcaaaacca     2220

ggagcagauc ccugcuuaua ucaaaacgga ggcugugaac auauuugcaa aaagaggcuu     2280

ggaacugcuu gguguucgug ucgugaaggu uuuaugaaag ccucagaugg gaaaacgugu     2340

cuggcucugg auggucauca gcuguuggca gguggugaag uugaucuaaa gaaccaagua     2400

acaccauugg acaucuuguc caagacuaga gugucagaag auaacauuac agaaucucaa     2460

cacaugcuag uggcugaaau caugguguca gaucaagaug acugugcucc ugugggaugc     2520

agcauguaug cucgguguau uucagaggga gaggaugcca caugucagug uuugaaagga     2580

uuugcugggg auggaaaacu auguucugau auagaugaau gugagauggg ugucccagug     2640

ugccccccug ccuccuccaa gugcaucaac accgaaggug guuaugucug ccggugcuca     2700

gaaggcuacc aaggagaugg gauucacugu cuugauauug augagugcca acugggggag     2760

cacagcugug gagagaaugc cagcugcaca aauacagagg gaggcuauac cugcaugugu     2820

gcuggacgcc ugucugaacc aggacugauu ugcccugacu cuacuccacc cccucaccuc     2880

agggaagaug accaccacua uuccguaaga aauagugacu cugaaugucc ccugucccac     2940

gauggguacu gccuccauga uggugugugc auguauauug aagcauugga caaguaugca     3000

ugcaacugug uuguuggcua caucggggag cgaugucagu accgagaccu gaaguggugg     3060

gaacugcgcc acgcuggcca cgggcagcag cagaagguca ucgugguggc ugucugcgug     3120

guggugcuug ucaugcugcu ccuccugagc cugugggggg cccacuacua caggacucag     3180

aagcugcuau cgaaaaaccc aaagaauccu uaugaggagu cgagcagaga ugugaggagu     3240

cgcaggccug cugacacuga ggaugggaug uccucuugcc cucaaccuug guuugugguu     3300

auaaaagaac accaagaccu caagaauggg ggucaaccag uggcugguga ggauggccag     3360

gcagcagaug ggucaaugca accaacuuca uggaggcagg agccccaguu auguggaaug     3420

ggcacagagc aaggcugcug gauuccagua uccagugaua agggcuccug uccccaggua     3480

auggagcgaa gcuuucauau gcccuccuau gggacacaga cccuugaagg gggugucgag     3540

aagccccauu cucuccuauc agcuaaccca uuauggcaac aaagggcccu ggacccacca     3600

caccaaaugg agcugacuca guga                                            3624


<210>  157
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  157
augaccgcgg ggaggaggau ggagaugcuc ugugccggca gggucccugc gcugcugcuc       60

ugccuggguu uccaucuucu acaggcaguc cucaguacaa cugugauucc aucauguauc      120

ccaggagagu ccagugauaa cugcacagcu uuaguucaga cagaagacaa uccacgugug      180

gcucaagugu caauaacaaa guguagcucu gacaugaaug gcuauuguuu gcauggacag      240

ugcaucuauc ugguggacau gagucaaaac uacugcaggu gugaaguggg uuauacuggu      300

guccgaugug aacacuucuu uuuaaccguc caccaaccuu uaagcaaaga auauguggcu      360

uugaccguga uucuuauuau uuuguuucuu aucacagucg ucgguuccac auauuauuuc      420

ugcagauggu acagaaaucg aaaaaguaaa gaaccaaaga aggaauauga gagaguuacc      480

ucaggggauc cagaguugcc gcaagucuga                                       510


<210>  158
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  158
auggcugaag gggaaaucac caccuucaca gcccugaccg agaaguuuaa ucugccucca       60

gggaauuaca agaagcccaa acuccucuac uguagcaacg ggggccacuu ccugaggauc      120

cuuccggaug gcacagugga ugggacaagg gacaggagcg accagcacau ucagcugcag      180

cucagugcgg aaagcguggg ggagguguau auaaagagua ccgagacugg ccaguacuug      240

gccauggaca ccgacgggcu uuuauacggc ucacagacac caaaugagga auguuuguuc      300

cuggaaaggc uggaggagaa ccauuacaac accuauauau ccaagaagca ugcagagaag      360

aauugguuug uuggccucaa gaagaauggg agcugcaaac gcgguccucg gacucacuau      420

ggccagaaag caaucuuguu ucucccccug ccagucucuu cugauuaa                   468


<210>  159
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  159
auggugggug uggggggugg agauguagaa gaugugacgc cgcggcccgg cgggugccag       60

auuagcggac gcggugcccg cgguugcaac gggaucccgg gcgcugcagc uugggaggcg      120

gcucucccca ggcggcgucc gcggagacac ccauccguga accccagguc ccgggccgcc      180

ggcucgccgc gcaccagggg ccggcggaca gaagagcggc cgagcggcuc gaggcugggg      240

gaccgcgggc gcggccgcgc gcugccgggc gggaggcugg ggggccgggg ccggggccgu      300

gccccggagc gggucggagg ccggggccgg ggccggggga cggcggcucc ccgcgcggcu      360

ccagcggcuc ggggaucccg gccgggcccc gcagggacca uggcagccgg gagcaucacc      420

acgcugcccg ccuugcccga ggauggcggc agcggcgccu ucccgcccgg ccacuucaag      480

gaccccaagc ggcuguacug caaaaacggg ggcuucuucc ugcgcaucca ccccgacggc      540

cgaguugacg ggguccggga gaagagcgac ccucacauca agcuacaacu ucaagcagaa      600

gagagaggag uugugucuau caaaggagug ugugcuaacc guuaccuggc uaugaaggaa      660

gauggaagau uacuggcuuc uaaauguguu acggaugagu guuucuuuuu ugaacgauug      720

gaaucuaaua acuacaauac uuaccgguca aggaaauaca ccaguuggua uguggcacug      780

aaacgaacug ggcaguauaa acuuggaucc aaaacaggac cugggcagaa agcuauacuu      840

uuucuuccaa ugucugcuaa gagcuga                                          867


<210>  160
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  160
augcacaaau ggauacugac auggauccug ccaacuuugc ucuacagauc augcuuucac       60

auuaucuguc uaguggguac uauaucuuua gcuugcaaug acaugacucc agagcaaaug      120

gcuacaaaug ugaacuguuc cagcccugag cgacacacaa gaaguuauga uuacauggaa      180

ggaggggaua uaagagugag aagacucuuc ugucgaacac agugguaccu gaggaucgau      240

aaaagaggca aaguaaaagg gacccaagag augaagaaua auuacaauau cauggaaauc      300

aggacagugg caguuggaau uguggcaauc aaaggggugg aaagugaauu cuaucuugca      360

augaacaagg aaggaaaacu cuaugcaaag aaagaaugca augaagauug uaacuucaaa      420

gaacuaauuc uggaaaacca uuacaacaca uaugcaucag cuaaauggac acacaacgga      480

ggggaaaugu uuguugccuu aaaucaaaag gggauuccug uaagaggaaa aaaaacgaag      540

aaagaacaaa aaacagccca cuuucuuccu auggcaauaa cuuaa                      585


<210>  161
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  161
augaagcugc ugccgucggu ggugcugaag cucuuucugg cugcaguucu cucggcacug       60

gugacuggcg agagccugga gcggcuucgg agagggcuag cugcuggaac cagcaacccg      120

gacccuccca cuguauccac ggaccagcug cuaccccuag gaggcggccg ggaccggaaa      180

guccgugacu ugcaagaggc agaucuggac cuuuugagag ucacuuuauc cuccaagcca      240

caagcacugg ccacaccaaa caaggaggag cacgggaaaa gaaagaagaa aggcaagggg      300

cuagggaaga agagggaccc augucuucgg aaauacaagg acuucugcau ccauggagaa      360

ugcaaauaug ugaaggagcu ccgggcuccc uccugcaucu gccacccggg uuaccaugga      420

gagagguguc augggcugag ccucccagug gaaaaucgcu uauauaccua ugaccacaca      480

accauccugg ccgugguggc uguggugcug ucaucugucu gucugcuggu caucgugggg      540

cuucucaugu uuagguacca uaggagagga gguuaugaug uggaaaauga agagaaagug      600

aaguugggca ugacuaauuc ccacuga                                          627


<210>  162
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  162
auguggguga ccaaacuccu gccagcccug cugcugcagc auguccuccu gcaucuccuc       60

cugcucccca ucgccauccc cuaugcagag ggacaaagga aaagaagaaa uacaauucau      120

gaauucaaaa aaucagcaaa gacuacccua aucaaaauag auccagcacu gaagauaaaa      180

accaaaaaag ugaauacugc agaccaaugu gcuaauagau guacuaggaa uaaaggacuu      240

ccauucacuu gcaaggcuuu uguuuuugau aaagcaagaa aacaaugccu cugguucccc      300

uucaauagca ugucaagugg agugaaaaaa gaauuuggcc augaauuuga ccucuaugaa      360

aacaaagacu acauuagaaa cugcaucauu gguaaaggac gcagcuacaa gggaacagua      420

ucuaucacua agaguggcau caaaugucag cccuggaguu ccaugauacc acacgaacac      480

agcuuuuugc cuucgagcua ucgggguaaa gaccuacagg aaaacuacug ucgaaauccu      540

cgaggggaag aagggggacc cugguguuuc acaagcaauc cagagguacg cuacgaaguc      600

ugugacauuc cucaguguuc agaaguugaa ugcaugaccu gcaaugggga gaguuaucga      660

ggucucaugg aucauacaga aucaggcaag auuugucagc gcugggauca ucagacacca      720

caccggcaca aauucuugcc ugaaagauau cccgacaagg gcuuugauga uaauuauugc      780

cgcaaucccg auggccagcc gaggccaugg ugcuauacuc uugacccuca cacccgcugg      840

gaguacugug caauuaaaac augcgcugac aauacuauga augacacuga uguuccuuug      900

gaaacaacug aaugcaucca aggucaagga gaaggcuaca ggggcacugu caauaccauu      960

uggaauggaa uuccauguca gcguugggau ucucaguauc cucacgagca ugacaugacu     1020

ccugaaaauu ucaagugcaa ggaccuacga gaaaauuacu gccgaaaucc agaugggucu     1080

gaaucacccu gguguuuuac cacugaucca aacauccgag uuggcuacug cucccaaauu     1140

ccaaacugug auaugucaca uggacaagau uguuaucgug ggaauggcaa aaauuauaug     1200

ggcaacuuau cccaaacaag aucuggacua acauguucaa ugugggacaa gaacauggaa     1260

gacuuacauc gucauaucuu cugggaacca gaugcaagua agcugaauga gaauuacugc     1320

cgaaauccag augaugaugc ucauggaccc uggugcuaca cgggaaaucc acucauuccu     1380

ugggauuauu gcccuauuuc ucguugugaa ggugauacca caccuacaau agucaauuua     1440

gaccaucccg uaauaucuug ugccaaaacg aaacaauugc gaguuguaaa ugggauucca     1500

acacgaacaa acauaggaug gaugguuagu uugagauaca gaaauaaaca uaucugcgga     1560

ggaucauuga uaaaggagag uuggguucuu acugcacgac aguguuuccc uucucgagac     1620

uugaaagauu augaagcuug gcuuggaauu caugaugucc acggaagagg agaugagaaa     1680

ugcaaacagg uucucaaugu uucccagcug guauauggcc cugaaggauc agaucugguu     1740

uuaaugaagc uugccaggcc ugcuguccug gaugauuuug uuaguacgau ugauuuaccu     1800

aauuauggau gcacaauucc ugaaaagacc aguugcagug uuuauggcug gggcuacacu     1860

ggauugauca acuaugaugg ccuauuacga guggcacauc ucuauauaau gggaaaugag     1920

aaaugcagcc agcaucaucg agggaaggug acucugaaug agucugaaau augugcuggg     1980

gcugaaaaga uuggaucagg accaugugag ggggauuaug guggcccacu uguuugugag     2040

caacauaaaa ugagaauggu ucuugguguc auuguuccug gucguggaug ugccauucca     2100

aaucguccug guauuuuugu ccgaguagca uauuaugcaa aauggauaca caaaauuauu     2160

uuaacauaua agguaccaca gucauag                                         2187


<210>  163
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  163
auggccaaag ccgcggcgau cggcaucgac cugggcacca ccuacuccug cgugggggug       60

uuccaacacg gcaaggugga gaucaucgcc aacgaccagg gcaaccgcac cacccccagc      120

uacguggccu ucacggacac cgagcggcuc aucggggaug cggccaagaa ccagguggcg      180

cugaacccgc agaacaccgu guuugacgcg aagcggcuga uuggccgcaa guucggcgac      240

ccgguggugc agucggacau gaagcacugg ccuuuccagg ugaucaacga cggagacaag      300

cccaaggugc aggugagcua caagggggag accaaggcau ucuaccccga ggagaucucg      360

uccauggugc ugaccaagau gaaggagauc gccgaggcgu accugggcua cccggugacc      420

aacgcgguga ucaccgugcc ggccuacuuc aacgacucgc agcgccaggc caccaaggau      480

gcggguguga ucgcggggcu caacgugcug cggaucauca acgagcccac ggccgccgcc      540

aucgccuacg gccuggacag aacgggcaag ggggagcgca acgugcucau cuuugaccug      600

ggcgggggca ccuucgacgu guccauccug acgaucgacg acggcaucuu cgaggugaag      660

gccacggccg gggacaccca ccuggguggg gaggacuuug acaacaggcu ggugaaccac      720

uucguggagg aguucaagag aaaacacaag aaggacauca gccagaacaa gcgagccgug      780

aggcggcugc gcaccgccug cgagagggcc aagaggaccc ugucguccag cacccaggcc      840

agccuggaga ucgacucccu guuugagggc aucgacuucu acacguccau caccagggcg      900

agguucgagg agcugugcuc cgaccuguuc cgaagcaccc uggagcccgu ggagaaggcu      960

cugcgcgacg ccaagcugga caaggcccag auucacgacc ugguccuggu cgggggcucc     1020

acccgcaucc ccaaggugca gaagcugcug caggacuucu ucaacgggcg cgaccugaac     1080

aagagcauca accccgacga ggcuguggcc uacggggcgg cggugcaggc ggccauccug     1140

augggggaca aguccgagaa cgugcaggac cugcugcugc uggacguggc uccccugucg     1200

cuggggcugg agacggccgg aggcgugaug acugcccuga ucaagcgcaa cuccaccauc     1260

cccaccaagc agacgcagau cuucaccacc uacuccgaca accaacccgg ggugcugauc     1320

cagguguacg agggcgagag ggccaugacg aaagacaaca aucuguuggg gcgcuucgag     1380

cugagcggca ucccuccggc ccccaggggc gugccccaga ucgaggugac cuucgacauc     1440

gaugccaacg gcauccugaa cgucacggcc acggacaaga gcaccggcaa ggccaacaag     1500

aucaccauca ccaacgacaa gggccgccug agcaaggagg agaucgagcg cauggugcag     1560

gaggcggaga aguacaaagc ggaggacgag gugcagcgcg agaggguguc agccaagaac     1620

gcccuggagu ccuacgccuu caacaugaag agcgccgugg aggaugaggg gcucaagggc     1680

aagaucagcg aggcggacaa gaagaaggug cuggacaagu gucaagaggu caucucgugg     1740

cuggacgcca acaccuuggc cgagaaggac gaguuugagc acaagaggaa ggagcuggag     1800

caggugugua accccaucau cagcggacug uaccagggug ccgguggucc cgggccuggg     1860

ggcuucgggg cucagggucc caagggaggg ucugggucag gccccaccau ugaggaggua     1920

gauuag                                                                1926


<210>  164
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  164
auggccaaag ccgcggcgau cggcaucgac cugggcacca ccuacuccug cgugggggug       60

uuccaacacg gcaaggugga gaucaucgcc aacgaccagg gcaaccgcac cacccccagc      120

uacguggccu ucacggacac cgagcggcuc aucggggaug cggccaagaa ccagguggcg      180

cugaacccgc agaacaccgu guuugacgcg aagcggcuga uuggccgcaa guucggcgac      240

ccgguggugc agucggacau gaagcacugg ccuuuccagg ugaucaacga cggagacaag      300

cccaaggugc aggugagcua caagggggag accaaggcau ucuaccccga ggagaucucg      360

uccauggugc ugaccaagau gaaggagauc gccgaggcgu accugggcua cccggugacc      420

aacgcgguga ucaccgugcc ggccuacuuc aacgacucgc agcgccaggc caccaaggau      480

gcggguguga ucgcggggcu caacgugcug cggaucauca acgagcccac ggccgccgcc      540

aucgccuacg gccuggacag aacgggcaag ggggagcgca acgugcucau cuuugaccug      600

ggcgggggca ccuucgacgu guccauccug acgaucgacg acggcaucuu cgaggugaag      660

gccacggccg gggacaccca ccuggguggg gaggacuuug acaacaggcu ggugaaccac      720

uucguggagg aguucaagag aaaacacaag aaggacauca gccagaacaa gcgagccgug      780

aggcggcugc gcaccgccug cgagagggcc aagaggaccc ugucguccag cacccaggcc      840

agccuggaga ucgacucccu guuugagggc aucgacuucu acacguccau caccagggcg      900

agguucgagg agcugugcuc cgaccuguuc cgaagcaccc uggagcccgu ggagaaggcu      960

cugcgcgacg ccaagcugga caaggcccag auucacgacc ugguccuggu cgggggcucc     1020

acccgcaucc ccaaggugca gaagcugcug caggacuucu ucaacgggcg cgaccugaac     1080

aagagcauca accccgacga ggcuguggcc uacggggcgg cggugcaggc ggccauccug     1140

augggggaca aguccgagaa cgugcaggac cugcugcugc uggacguggc uccccugucg     1200

cuggggcugg agacggccgg aggcgugaug acugcccuga ucaagcgcaa cuccaccauc     1260

cccaccaagc agacgcagau cuucaccacc uacuccgaca accaacccgg ggugcugauc     1320

cagguguacg agggcgagag ggccaugacg aaagacaaca aucuguuggg gcgcuucgag     1380

cugagcggca ucccuccggc ccccaggggc gugccccaga ucgaggugac cuucgacauc     1440

gaugccaacg gcauccugaa cgucacggcc acggacaaga gcaccggcaa ggccaacaag     1500

aucaccauca ccaacgacaa gggccgccug agcaaggagg agaucgagcg cauggugcag     1560

gaggcggaga aguacaaagc ggaggacgag gugcagcgcg agaggguguc agccaagaac     1620

gcccuggagu ccuacgccuu caacaugaag agcgccgugg aggaugaggg gcucaagggc     1680

aagaucagcg aggcggacaa gaagaagguu cuggacaagu gucaagaggu caucucgugg     1740

cuggacgcca acaccuuggc cgagaaggac gaguuugagc acaagaggaa ggagcuggag     1800

caggugugua accccaucau cagcggacug uaccagggug ccgguggucc cgggccuggc     1860

ggcuucgggg cucagggucc caagggaggg ucugggucag gcccuaccau ugaggaggug     1920

gauuag                                                                1926


<210>  165
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  165
auggcuacug ccaagggaau cgccauaggc aucgaccugg gcaccaccua cuccugugug       60

gggguguucc agcacggcaa gguggagauc aucgccaacg accagggcaa ccgcaccacc      120

cccagcuacg uggccuucac agacaccgag cggcucauug gggaugcggc caagaaccag      180

guagcaauga auccccagaa cacuguuuuu gaugcuaaac gucugaucgg caggaaauuu      240

aaugauccug uuguacaagc agauaugaaa cuuuggccuu uucaagugau uaaugaagga      300

ggcaagccca aaguccuugu guccuacaaa ggggagaaua aagcuuucua cccugaggaa      360

aucucuucga ugguauugac uaaguugaag gagacugcug aggccuuuuu gggccacccu      420

gucaccaaug cagugauuac cgugccagcc uauuucaaug acucucaacg ucaggcuacu      480

aaggaugcag gugugauugc uggacuuaau gugcuaagaa ucaucaauga gcccacggcu      540

gcugccauug ccuaugguuu agauaaagga ggucaaggag aacgacaugu ccugauuuuu      600

gaucugggug gaggcacauu ugauguguca auucugacca uagaugaugg gauuuuugag      660

guaaaggcca cugcugggga cacucaccug gguggggagg acuuugacaa caggcuugug      720

agccacuucg uggaggaguu caagaggaaa cacaaaaagg acaucagcca gaacaagcga      780

gccgugaggc ggcugcgcac cgccugcgag agggccaaga ggacccuguc guccagcacc      840

caggccaacc uagaaauuga uucacuuuau gaaggcauug acuucuauac auccaucacc      900

agagcucgau uugaagaguu gugugcagac cuguuuaggg guacccugga gccuguagaa      960

aaagcgcuuc gggaugccaa gauggauaag gcuaaaaucc augacauugu uuuaguaggg     1020

ggcuccaccc gcauccccaa ggugcagcgg cugcuucagg acuacuucaa uggacgugau     1080

cucaacaaga gcaucaaccc ugaugaggcc guagcauaug gggcugcggu acaagcagcc     1140

auccugaugg gggacaaguc ugagaaggua caggaccugc ugcugcugga cguggcuccc     1200

cugucccugg ggcuggagac ggcugggggc gugaugacug cccugauaaa gcgcaacucc     1260

accaucccca ccaagcagac acagauuuuc accaccuacu cugacaacca acccggggug     1320

cugauccagg uguaugaggg cgagagggcc augacaaagg acaacaaccu gcuggggcgg     1380

uuugaccuga cuggaauccc uccagcaccc aggggaguuc cucagaucga ggugacguuu     1440

gacauugaug ccaaugguau ucucaauguc acagccacgg acaagagcac cggcaaggug     1500

aacaagauca ccaucaccaa ugacaagggc cgccugagca aggaggagau ugagcgcaug     1560

guucuggaug cugagaaaua uaaagcugaa gaugaggucc agagggagaa aauugcugca     1620

aagaaugccu uagaauccua ugcuuuuaac augaagagug uugugaguga ugaagguuug     1680

aagggcaaga uuagugaguc ugauaaaaau aaaauauugg auaaaugcaa cgagcuccuu     1740

ucguggcugg aggucaauca acuggcagag aaagaugagu uugaucauaa gagaaaggaa     1800

uuggagcaga uguguaaccc uaucaucaca aaacucuacc aaggaggaug cacugggccu     1860

gccugcggaa caggguaugu gccuggaagg ccugccacag gccccacaau ugaagaagua     1920

gauuaa                                                                1926


<210>  166
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  166
augucugccc guggcccggc uaucggcauc gaccugggca ccaccuauuc gugcgucggg       60

gucuuccaac auggcaaggu ggagaucauc gccaacgacc agggcaaucg caccaccccc      120

agcuacgugg ccuucacgga caccgagcgc cucaucggcg acgccgccaa gaaccaggug      180

gccaugaacc ccaccaacac caucuucgac gccaagaggc ugauuggacg gaaauucgag      240

gaugccacag ugcagucgga uaugaaacac uggccguucc ggguggugag cgagggaggc      300

aagcccaaag ugcaaguaga guacaagggg gagaccaaga ccuucuuccc agaggagaua      360

uccuccaugg uccucacgaa gaugaaggag aucgcggaag ccuaccuggg gggcaaggug      420

cacagcgcgg ucauaacggu cccggccuau uucaacgacu cgcagcgcca ggccaccaag      480

gacgcaggca ccaucacggg gcucaaugug cugcgcauca ucaacgagcc cacggcggcg      540

gccaucgccu acggccugga caagaagggc ugcgcgggcg gcgagaagaa cgugcucauc      600

uuugaccugg gcgguggcac uuucgacgug uccauccuga ccaucgagga uggcaucuuc      660

gaggugaagu ccacggccgg cgacacccac cugggcggug aggacuucga caaccgcaug      720

gugagccacc uggcggagga guucaagcgc aagcacaaga aggacauugg gcccaacaag      780

cgcgccguga ggcggcugcg caccgcuugc gagcgcgcca agcgcacccu gagcucgucc      840

acgcaggcga gcaucgagau cgacucgcuc uacgagggcg uggacuucua uacguccauc      900

acgcgcgccc gcuucgagga gcucaaugcc gaccucuuuc gcgggacccu ggagccggug      960

gagaaggcgc ugcgcgacgc caagcuggac aagggccaga uccaggagau cgugcuggug     1020

ggcggcucca cucguauccc caagauccag aagcugcugc aggauuucuu caacggcaag     1080

gagcugaaca agagcaucaa ccccgacgag gcgguggccu auggcgccgc ggugcaggcg     1140

gccauccuca ucggcgacaa aucagagaau gugcaggacc ugcugcuacu cgacgugacc     1200

ccguugucgc ugggcaucga gacagcuggc ggugucauga ccccacucau caagaggaac     1260

accacgaucc ccaccaagca gacgcagacc uucaccaccu acucggacaa ccagagcagc     1320

guacuggugc agguauacga gggcgaacgg gccaugacca aggacaauaa ccugcugggc     1380

aaguucgacc ugaccgggau ucccccugcg ccucgcgggg ucccccaaau cgagguuacc     1440

uucgacauug acgccaaugg cauccuuaac guuaccgccg ccgacaagag caccgguaag     1500

gaaaacaaaa ucaccaucac caaugacaaa ggucgucuga gcaaggacga cauugaccgg     1560

auggugcagg aggcggagcg guacaaaucg gaagaugagg cgaaucgcga ccgagucgcg     1620

gccaaaaacg cccuggaguc cuauaccuac aacaucaagc agacggugga agacgagaaa     1680

cugaggggca agauuagcga gcaggacaaa aacaagaucc ucgacaagug ucaggaggug     1740

aucaacuggc ucgaccgaaa ccagauggca gagaaagaug aguaugaaca caagcagaaa     1800

gagcucgaaa gaguuugcaa ccccaucauc agcaaacuuu accaaggugg uccuggcggc     1860

ggcagcggcg gcggcgguuc aggagccucc gggggaccca ccaucgaaga aguggacuaa     1920


<210>  167
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  167
augucggugg ugggcauaga ccugggcuuc cagagcugcu acgucgcugu ggcccgcgcc       60

ggcggcaucg agacuaucgc uaaugaguau agcgaccgcu gcacgccggc uugcauuucu      120

uuugguccua agaaucguuc aauuggagca gcagcuaaaa gccagguaau uucuaaugca      180

aagaacacag uccaaggauu uaaaagauuc cauggccgag cauucucuga uccauuugug      240

gaggcagaaa aaucuaaccu ugcauaugau auugugcagu ugccuacagg auuaacaggu      300

auaaagguga cauauaugga ggaagagcga aauuuuacca cugagcaagu gacugccaug      360

cuuuugucca aacugaagga gacagccgaa aguguucuua agaagccugu aguugacugu      420

guuguuucgg uuccuuguuu cuauacugau gcagaaagac gaucagugau ggaugcaaca      480

cagauugcug gucuuaauug cuugcgauua augaaugaaa ccacugcagu ugcucuugca      540

uauggaaucu auaagcagga ucuuccugcc uuagaagaga aaccaagaaa uguaguuuuu      600

guagacaugg gccacucugc uuaucaaguu ucuguaugug cauuuaauag aggaaaacug      660

aaaguucugg ccacugcauu ugacacgaca uugggaggua gaaaauuuga ugaaguguua      720

guaaaucacu ucugugaaga auuugggaag aaauacaagc uagacauuaa guccaaaauc      780

cgugcauuau uacgacucuc ucaggagugu gagaaacuca agaaauugau gagugcaaau      840

gcuucagauc ucccuuugag cauugaaugu uuuaugaaug auguugaugu aucuggaacu      900

augaauagag gcaaauuucu ggagaugugc aaugaucucu uagcuagagu ggagccacca      960

cuucguagug uuuuggaaca aaccaaguua aagaaagaag auauuuaugc aguggagaua     1020

guugguggug cuacacgaau cccugcggua aaagagaaga ucagcaaauu uuucgguaaa     1080

gaacuuagua caacauuaaa ugcugaugaa gcugucacuc gaggcugugc auugcagugu     1140

gccaucuuau cgccugcuuu caaagucaga gaauuuucua ucacugaugu aguaccauau     1200

ccaauaucuc ugagauggaa uucuccagcu gaagaagggu caagugacug ugaagucuuu     1260

uccaaaaauc augcugcucc uuucucuaaa guucuuacau uuuauagaaa ggaaccuuuc     1320

acucuugagg ccuacuacag cucuccucag gauuugcccu auccagaucc ugcuauagcu     1380

caguuuucag uucagaaagu cacuccucag ucugauggcu ccaguucaaa agugaaaguc     1440

aaaguucgag uaaaugucca uggcauuuuc agugugucca gugcaucuuu aguggagguu     1500

cacaagucug aggaaaauga ggagccaaug gaaacagauc agaaugcaaa ggaggaagag     1560

aagaugcaag uggaccagga ggaaccacau guugaagagc aacagcagca gacaccagca     1620

gaaaauaagg cagagucuga agaaauggag accucucaag cuggauccaa ggauaaaaag     1680

auggaccaac caccccaagc caagaaggca aaagugaaga ccaguacugu ggaccugcca     1740

aucgagaauc agcuauuaug gcagauagac agagagaugc ucaacuugua cauugaaaau     1800

gaggguaaga ugaucaugca ggauaaacug gagaaggagc ggaaugaugc uaagaacgca     1860

guggaggaau auguguauga aaugagagac aagcuuagug gugaauauga gaaguuugug     1920

agugaagaug aucguaacag uuuuacuuug aaacuggaag auacugaaaa uugguuguau     1980

gaggauggag aagaccagcc aaagcaaguu uauguugaua aguuggcuga auuaaaaaau     2040

cuaggucaac cuauuaagau acguuuccag gaaucugaag aacgaccaaa auuauuugaa     2100

gaacuaggga aacagaucca acaguauaug aaaauaauca gcucuuucaa aaacaaggag     2160

gaccaguaug aucauuugga ugcugcugac augacaaagg uagaaaaaag cacaaaugaa     2220

gcaauggagu ggaugaauaa caagcuaaau cugcagaaca agcagaguuu gaccauggau     2280

ccaguuguca agucaaaaga gauugaagcu aaaauuaagg agcugacaag uacuuguagc     2340

ccuauaauuu caaagcccaa acccaaagug gaaccuccaa aagaggaaca aaaaaaugca     2400

gagcagaaug gaccagugga uggacaagga gacaacccag gcccccaggc ugcugagcag     2460

gguacagaca cagcugugcc uucggauuca gacaagaagc uuccugaaau ggacauugau     2520

uga                                                                   2523


<210>  168
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  168
augucugugg uuggcauuga ccucggcuuu cucaacugcu acauugcugu cgcgagaagu       60

ggcggcaucg agaccaucgc caaugaguac agcgacaggu guaccccggc cuguauauca      120

uugggaucaa gaacucgagc cauuggaaau gcagcaaaga gccagauagu cacgaacgua      180

agaaauacaa uucauggcuu caaaaagcuu caugggcgau cauuugauga ucccauugug      240

caaacugaaa ggaucaggcu ucccuaugaa cugcagaaaa ugccuaaugg aagugcagga      300

guuaaggugc gguacuuaga ggaagagaga ccuuuugcaa uugagcaagu uacuggaaug      360

cuguuagcca agcuuaaaga gacuucagaa aaugcuuuga agaaaccagu ggcugacugu      420

gugauuucaa uuccuagcuu uuuuacugau gccgagagaa gaucugugau ggcugcagcc      480

cagguugcag gcuuaaauug uuuaagguug augaaugaaa cuacugcagu ugcacuggcg      540

uauggaauuu auaaacagga ucuuccccca uuagaugaga aaccaagaaa uguaguauuu      600

auugauaugg gacauucugc cuaucagguc uugguuugug cuuuuaacaa aggaaaacuu      660

aaagucuugg cuacuaccuu ugauccauau uuggguggca ggaacuuuga ugaggcuuua      720

guagacuacu ucugugauga guucaagacc aaauauaaga uaaaugugaa agaaaacucu      780

cgggccuugu ugcguuuaua ucaggaaugu gaaaaacuaa agaagcuaau gagugcaaau      840

gcaucagauc uuccauugaa cauugagugu uucaugaaug accuugaugu uucuaguaaa      900

augaacaggg cucaauuuga acaacugugu gcuucccuuu uggccagggu ugaaccaccu      960

uuaaaagcag uaauggaaca agcuaacuua caacgugaag acauuaguag uauagaaauu     1020

guaggaggag caacacgaau uccugcagug aaagaacaaa ucacuaaauu cuuucuuaaa     1080

gacauaagua ccacauuaaa ugcugaugaa gcuguugcaa gaggaugugc guuacagugu     1140

gcgauucucu caccagcauu uaaagugcgu gaauuuucca uaacagaccu uguucccuau     1200

ucaaucacau uaagguggaa gaccucuuuu gaagauggaa guggggaaug ugaaguuuuc     1260

uguaagaacc auccugcccc auucucaaaa gucauuacuu uccacaagaa ggaaccauuu     1320

gaacuagaag cauuuuauac uaauuuacau gaagugccuu auccugaugc aagaauuggg     1380

agcuucacua uucagaaugu uuuuccacag ucugauggug auaguuccaa agugaagguu     1440

aaaguucgug uuaacaucca uggaaucuuc aguguggcua gcgcaucagu aauugagaag     1500

caaaauuugg aaggcgauca cagugaugcu ccaauggaga cagaaacuuc auuuaaaaau     1560

gaaaacaaag auaauaugga uaaaaugcag guugaucaag aagaagggca ucaaaaaugu     1620

caugcugaac acacuccaga agaggaaauu gaucauacag gagccaaaac aaagucagcu     1680

gucucagaca aacaagaccg auuaaaucag acacuuaaaa aaggaaaagu caaaaguauu     1740

gaucuaccga uccagaguag ccuauguaga caacuaggcc aagaucuucu caacagcuac     1800

auugaaaaug aggggaagau gaucaugcaa gauaaguuag agaaagaaag aaaugaugcu     1860

aagaaugccg uugaagaaua uguauaugau uuuagagaca ggcugggcac ugucuaugaa     1920

aaauucauca cuccagaaga cuugaguaaa cugucugcag uauuggaaga cacagaaaau     1980

uggcuuuaug aagacggaga ggaccaaccu aaacaaguuu auguggauaa gcuucaagaa     2040

cuaaagaaau acggccagcc uauucaaaug aaguacaugg agcaugaaga gagaccaaaa     2100

gccuuaaaug acuugggaaa aaagauccaa cuugucauga aagugauaga agcuuauaga     2160

aacaaggaug aaagauauga ucaucuggau ccuacugaaa uggaaaaggu ugaaaaaugu     2220

aucagugaug ccaugaguug gcugaauagu aagaugaaug cacagaacaa acuaagucuc     2280

acucaagauc cugugguaaa aguuucagaa auaguagcaa agucaaagga acuggauaau     2340

uucuguaacc ccaucauuua caagcccaaa ccaaaagcag aaguuccuga agacaaacca     2400

aaagcuaaua gugaacacaa uggcccaaug gauggacaga guggaacuga aacuaaauca     2460

gauucaacaa aagacagcuc acagcauacu aaauccucug gagagaugga aguggacuaa     2520


<210>  169
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  169
augaagcucu cccugguggc cgcgaugcug cugcugcuca gcgcggcgcg ggccgaggag       60

gaggacaaga aggaggacgu gggcacggug gucggcaucg accuggggac caccuacucc      120

ugcgucggcg uguucaagaa cggccgcgug gagaucaucg ccaacgauca gggcaaccgc      180

aucacgccgu ccuaugucgc cuucacuccu gaaggggaac gucugauugg cgaugccgcc      240

aagaaccagc ucaccuccaa ccccgagaac acggucuuug acgccaagcg gcucaucggc      300

cgcacgugga augacccguc ugugcagcag gacaucaagu ucuugccguu caaggugguu      360

gaaaagaaaa cuaaaccaua cauucaaguu gauauuggag gugggcaaac aaagacauuu      420

gcuccugaag aaauuucugc caugguucuc acuaaaauga aagaaaccgc ugaggcuuau      480

uugggaaaga agguuaccca ugcaguuguu acuguaccag ccuauuuuaa ugaugcccaa      540

cgccaagcaa ccaaagacgc uggaacuauu gcuggccuaa auguuaugag gaucaucaac      600

gagccuacgg cagcugcuau ugcuuauggc cuggauaaga gggaggggga gaagaacauc      660

cugguguuug accugggugg cggaaccuuc gaugugucuc uucucaccau ugacaauggu      720

gucuucgaag uuguggccac uaauggagau acucaucugg guggagaaga cuuugaccag      780

cgugucaugg aacacuucau caaacuguac aaaaagaaga cgggcaaaga ugucaggaaa      840

gacaauagag cugugcagaa acuccggcgc gagguagaaa aggccaaacg ggcccugucu      900

ucucagcauc aagcaagaau ugaaauugag uccuucuaug aaggagaaga cuuuucugag      960

acccugacuc gggccaaauu ugaagagcuc aacauggauc uguuccgguc uacuaugaag     1020

cccguccaga aaguguugga agauucugau uugaagaagu cugauauuga ugaaauuguu     1080

cuuguuggug gcucgacucg aauuccaaag auucagcaac ugguuaaaga guucuucaau     1140

ggcaaggaac caucccgugg cauaaaccca gaugaagcug uagcguaugg ugcugcuguc     1200

caggcuggug ugcucucugg ugaucaagau acaggugacc ugguacugcu ugauguaugu     1260

ccccuuacac uugguauuga aacuguggga ggugucauga ccaaacugau uccaaggaac     1320

acaguggugc cuaccaagaa gucucagauc uuuucuacag cuucugauaa ucaaccaacu     1380

guuacaauca aggucuauga aggugaaaga ccccugacaa aagacaauca ucuucugggu     1440

acauuugauc ugacuggaau uccuccugcu ccucgugggg ucccacagau ugaagucacc     1500

uuugagauag augugaaugg uauucuucga gugacagcug aagacaaggg uacagggaac     1560

aaaaauaaga ucacaaucac caaugaccag aaucgccuga caccugaaga aaucgaaagg     1620

augguuaaug augcugagaa guuugcugag gaagacaaaa agcucaagga gcgcauugau     1680

acuagaaaug aguuggaaag cuaugccuau ucucuaaaga aucagauugg agauaaagaa     1740

aagcugggag guaaacuuuc cucugaagau aaggagacca uggaaaaagc uguagaagaa     1800

aagauugaau ggcuggaaag ccaccaagau gcugacauug aagacuucaa agcuaagaag     1860

aaggaacugg aagaaauugu ucaaccaauu aucagcaaac ucuauggaag ugcaggcccu     1920

cccccaacug gugaagagga uacagcagaa aaagaugagu uguag                     1965


<210>  170
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  170
augcaggccc cacgggagcu cgcggugggc aucgaccugg gcaccaccua cucgugcgug       60

ggcguguuuc agcagggccg cguggagauc cuggccaacg accagggcaa ccgcaccacg      120

cccagcuacg uggccuucac cgacaccgag cggcuggucg gggacgcggc caagagccag      180

gcggcccuga acccccacaa caccguguuc gaugccaagc ggcugaucgg gcgcaaguuc      240

gcggacacca cggugcaguc ggacaugaag cacuggcccu uccggguggu gagcgagggc      300

ggcaagccca aggugcgcgu augcuaccgc ggggaggaca agacguucua ccccgaggag      360

aucucgucca uggugcugag caagaugaag gagacggccg aggcguaccu gggccagccc      420

gugaagcacg cagugaucac cgugcccgcc uauuucaaug acucgcagcg ccaggccacc      480

aaggacgcgg gggccaucgc ggggcucaac guguugcgga ucaucaauga gcccacggca      540

gcugccaucg ccuaugggcu ggaccggcgg ggcgcgggag agcgcaacgu gcucauuuuu      600

gaccugggug ggggcaccuu cgaugugucg guucucucca uugacgcugg ugucuuugag      660

gugaaagcca cugcuggaga uacccaccug ggaggagagg acuucgacaa ccggcucgug      720

aaccacuuca uggaagaauu ccggcggaag caugggaagg accugagcgg gaacaagcgu      780

gcccugcgca ggcugcgcac agccugugag cgcgccaagc gcacccuguc cuccagcacc      840

caggccaccc uggagauaga cucccuguuc gagggcgugg acuucuacac guccaucacu      900

cgugcccgcu uugaggaacu gugcucagac cucuuccgca gcacccugga gccgguggag      960

aaggcccugc gggaugccaa gcuggacaag gcccagauuc augacgucgu ccuggugggg     1020

ggcuccacac gcauccccaa ggugcagaag uugcugcagg acuucuucaa cggcaaggag     1080

cugaacaaga gcaucaaccc ugaugaggcu guggccuaug gggcugcugu gcaggcggcc     1140

guguugaugg gggacaaaug ugagaaagug caggaucucc ugcugcugga uguggcuccc     1200

cugucucugg ggcuggagac agcagguggg gugaugacca cgcugaucca gaggaacgcc     1260

acuaucccca ccaagcagac ccagacuuuc accaccuacu cggacaacca gccugggguc     1320

uucauccagg uguaugaggg ugagagggcc augaccaagg acaacaaccu gcuggggcgu     1380

uuugaacuca guggcauccc uccugcccca cguggagucc cccagauaga ggugacuuuu     1440

gacauugaug cuaauggcau ccugagcgug acagccacug acaggagcac agguaaggcu     1500

aacaagauca ccaucaccaa ugacaagggc cggcugagca aggaggaggu ggagaggaug     1560

guucaugaag ccgagcagua caaggcugag gaugaggccc agagggacag aguggcugcc     1620

aaaaacucgc uggaggccca ugucuuccau gugaaagguu cuuugcaaga ggaaagccuu     1680

agggacaaga uucccgaaga ggacaggcgc aaaaugcaag acaagugucg ggaaguccuu     1740

gccuggcugg agcacaacca gcuggcagag aaggaggagu augagcauca gaagagggag     1800

cuggagcaaa ucugucgccc caucuucucc aggcucuaug gggggccugg ugucccuggg     1860

ggcagcaguu guggcacuca agcccgccag ggggacccca gcaccggccc caucauugag     1920

gagguugauu ga                                                         1932


<210>  171
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__P48741__HsHSPA7

<400>  171
augcaggccc cacgggagcu cgcggugggc aucgaccugg gcaccaccua cucgugcgug       60

ggcguguuuc agcagggccg cguggagauc cuggccaacg accagggcaa ccgcaccacg      120

cccagcuacg uggccuucac cgacaccgag cggcuggucg gggacgcggc caagagccag      180

gcggcccuga acccccacaa caccguguuc gaugccaagc ggcugaucgg gcgcaaguuc      240

gcggacacca cggugcaguc ggacaugaag cacuggcccu uccagguggu gagcgagggc      300

ggcaagccca aggugcgcgu augcuaccgc ggggaggaca agacguucua ccccgaggag      360

aucucgucca uggugcugag caagaugaag gagacggccg aggcguaccu gggccagccc      420

gugaagcacg cagugaucac cgugcccacc uauuucagua acucgcagcg ccaggccacc      480

aaggacgcgg gggccaucgc ggggcucaag gugcugccga ucaucaauga ggccacggca      540

gcagccaucg ccuaugggcu ggaccggcgg ggcgcgggaa agcgcaacgu gcucauuuuu      600

gaccugggug ggggcaccuu cgaugugucg guucucucca uugacgccgg ugucuuugag      660

gugaaagcca cugcuggaga uacccaccug ggaggagagg acuucgacaa ccggcucgug      720

aaccacuuca uggaagaauu ccggcggaag caugggaagg accugagcgg gaacaagcgu      780

gcccugcgca ggcugcgcac agccugugag cgcgccaagc gcaccccguc cuccagcacc      840

caggccaccc uggagauaga cucccuguuc gagggcgugg acuucuacaa guccaucacu      900

cgugcccgcu uugaggaacu gugcucagac cucuuccgca gcacccugga gccgguggag      960

aaggcccugc gggaugccaa gcuggacaag gcccagauuc augacuucgu ccugggggga     1020

gggcuccacu cgcaucccca aggugcagaa guugcugcag gacuucuuca acggcaagga     1080

gcugaacaag agcaucaacc cuga                                            1104


<210>  172
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  172
auguccaagg gaccugcagu ugguauugau cuuggcacca ccuacucuug uguggguguu       60

uuccagcacg gaaaagucga gauaauugcc aaugaucagg gaaaccgaac cacuccaagc      120

uaugucgccu uuacggacac ugaacgguug aucggugaug ccgcaaagaa ucaaguugca      180

augaacccca ccaacacagu uuuugaugcc aaacgucuga uuggacgcag auuugaugau      240

gcuguugucc agucugauau gaaacauugg cccuuuaugg uggugaauga ugcuggcagg      300

cccaaggucc aaguagaaua caagggagag accaaaagcu ucuauccaga ggaggugucu      360

ucuaugguuc ugacaaagau gaaggaaauu gcagaagccu accuugggaa gacuguuacc      420

aaugcugugg ucacagugcc agcuuacuuu aaugacucuc agcgucaggc uaccaaagau      480

gcuggaacua uugcuggucu caauguacuu agaauuauua augagccaac ugcugcugcu      540

auugcuuacg gcuuagacaa aaagguugga gcagaaagaa acgugcucau cuuugaccug      600

ggagguggca cuuuugaugu gucaauccuc acuauugagg auggaaucuu ugaggucaag      660

ucuacagcug gagacaccca cuugggugga gaagauuuug acaaccgaau ggucaaccau      720

uuuauugcug aguuuaagcg caagcauaag aaggacauca gugagaacaa gagagcugua      780

agacgccucc guacugcuug ugaacgugcu aagcguaccc ucucuuccag cacccaggcc      840

aguauugaga ucgauucucu cuaugaagga aucgacuucu auaccuccau uacccgugcc      900

cgauuugaag aacugaaugc ugaccuguuc cguggcaccc uggacccagu agagaaagcc      960

cuucgagaug ccaaacuaga caagucacag auucaugaua uuguccuggu uggugguucu     1020

acucguaucc ccaagauuca gaagcuucuc caagacuucu ucaauggaaa agaacugaau     1080

aagagcauca acccugauga agcuguugcu uauggugcag cuguccaggc agccaucuug     1140

ucuggagaca agucugagaa uguucaagau uugcugcucu uggaugucac uccucuuucc     1200

cuugguauug aaacugcugg uggagucaug acuguccuca ucaagcguaa uaccaccauu     1260

ccuaccaagc agacacagac cuucacuacc uauucugaca accagccugg ugugcuuauu     1320

cagguuuaug aaggcgagcg ugccaugaca aaggauaaca accugcuugg caaguuugaa     1380

cucacaggca uaccuccugc accccgaggu guuccucaga uugaagucac uuuugacauu     1440

gaugccaaug guauacucaa ugucucugcu guggacaaga guacgggaaa agagaacaag     1500

auuacuauca cuaaugacaa gggccguuug agcaaggaag acauugaacg uaugguccag     1560

gaagcugaga aguacaaagc ugaagaugag aagcagaggg acaagguguc auccaagaau     1620

ucacuugagu ccuaugccuu caacaugaaa gcaacuguug aagaugagaa acuucaaggc     1680

aagauuaacg augaggacaa acagaagauu cuggacaagu guaaugaaau uaucaacugg     1740

cuugauaaga aucagacugc ugagaaggaa gaauuugaac aucaacagaa agagcuggag     1800

aaaguuugca accccaucau caccaagcug uaccagagug caggaggcau gccaggagga     1860

augccugggg gauuuccugg ugguggagcu ccucccucug guggugcuuc cucagggccc     1920

accauugaag agguugauua a                                               1941


<210>  173
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  173
augauaagug ccagccgagc ugcagcagcc cgucucgugg gcgccgcagc cucccggggc       60

ccuacggccg cccgccacca ggauagcugg aauggccuua gucaugaggc uuuuagacuu      120

guuucaaggc gggauuaugc aucagaagca aucaagggag caguuguugg uauugauuug      180

gguacuacca acuccugcgu ggcaguuaug gaagguaaac aagcaaaggu gcuggagaau      240

gccgaaggug ccagaaccac cccuucaguu guggccuuua cagcagaugg ugagcgacuu      300

guuggaaugc cggccaagcg acaggcuguc accaacccaa acaauacauu uuaugcuacc      360

aagcgucuca uuggccggcg auaugaugau ccugaaguac agaaagacau uaaaaauguu      420

cccuuuaaaa uuguccgugc cuccaauggu gaugccuggg uugaggcuca ugggaaauug      480

uauucuccga gucagauugg agcauuugug uugaugaaga ugaaagagac ugcagaaaau      540

uacuuggggc acacagcaaa aaaugcugug aucacagucc cagcuuauuu caaugacucg      600

cagagacagg ccacuaaaga ugcuggccag auaucuggac ugaaugugcu ucgggugauu      660

aaugagccca cagcugcugc ucuugccuau ggucuagaca aaucagaaga caaagucauu      720

gcuguauaug auuuaggugg uggaacuuuu gauauuucua uccuggaaau ucagaaagga      780

guauuugagg ugaaauccac aaauggggau accuucuuag guggggaaga cuuugaccag      840

gccuugcuac ggcacauugu gaaggaguuc aagagagaga cagggguuga uuugacuaaa      900

gacaacaugg cacuucagag gguacgggaa gcugcugaaa aggcuaaaug ugaacucucc      960

ucaucugugc agacugacau caauuugccc uaucuuacaa uggauucuuc uggacccaag     1020

cauuugaaua ugaaguugac ccgugcucaa uuugaaggga uugucacuga ucuaaucaga     1080

aggacuaucg cuccaugcca aaaagcuaug caagaugcag aagucagcaa gagugacaua     1140

ggagaaguga uucuuguggg uggcaugacu aggaugccca agguucagca gacuguacag     1200

gaucuuuuug gcagagcccc aaguaaagcu gucaauccug augaggcugu ggccauugga     1260

gcugccauuc agggaggugu guuggccggc gaugucacgg augugcugcu ccuugauguc     1320

acuccccugu cucuggguau ugaaacucua ggaggugucu uuaccaaacu uauuaauagg     1380

aauaccacua uuccaaccaa gaagagccag guauucucua cugccgcuga uggucaaacg     1440

caaguggaaa uuaaagugug ucagggugaa agagagaugg cuggagacaa caaacuccuu     1500

ggacaguuua cuuugauugg aauuccacca gccccucgug gaguuccuca gauugaaguu     1560

acauuugaca uugaugccaa ugggauagua cauguuucug cuaaagauaa aggcacagga     1620

cgugagcagc agauuguaau ccagucuucu gguggauuaa gcaaagauga uauugaaaau     1680

augguuaaaa augcagagaa auaugcugaa gaagaccggc gaaagaagga acgaguugaa     1740

gcaguuaaua uggcugaagg aaucauucac gacacagaaa ccaagaugga agaauucaag     1800

gaccaauuac cugcugauga gugcaacaag cugaaagaag agauuuccaa aaugagggag     1860

cuccuggcua gaaaagacag cgaaacagga gaaaauauua gacaggcagc auccucucuu     1920

cagcaggcau cacugaagcu guucgaaaug gcauacaaaa agauggcauc ugagcgagaa     1980

ggcucuggaa guucuggcac uggggaacaa aaggaagauc aaaaggagga aaaacaguaa     2040


<210>  174
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  174
auggcggaca aggaggccgg cggcagcgac gggccccgag aaacggcucc cacaucugca       60

uauucaucuc cagcccggag ucuuggggac acaggaauaa cgccucuguc ccccucccau      120

auugugaacg acacugacuc caacgucuca gaacagcagu cauuucucgu ggugguggcc      180

gucgacuuug ggaccacauc caguggcuau gccuacagcu ucaccaagga gccggaaugc      240

auccauguga ugaggcgaug ggagggaggu gacccuggug uguccaauca gaagacucca      300

accaccaucu ugcugacucc cgagaggaag uuccacagcu ucggguaugc cgccagggac      360

uuuuaccaug accuggaucc caaugaggcc aagcaguggc uguaccugga gaaguucaag      420

augaagcugc acaccacugg ggaccucacc auggauacag accugacggc agcaaauggc      480

aagaaaguca aagcccuuga aaucuuugcu uaugcccugc aguacuuuaa ggagcaggcg      540

cugaaggagc ugagugacca ggcggguucg gaguucgaga acucugaugu cagauggguc      600

aucacggugc cugccaucug gaagcagccg gccaagcagu ucaugagaca agcugccuac      660

caggcaggcc uggccucccc cgagaacucg gagcagcuca ucauugccuu ggagccugag      720

gcagccucua ucuacugccg aaagcugcgg cuacaccaga ugauugagcu gagcagcaag      780

gcagccguca auggguacag cggcagugac acaguaggag cuggguuuac acaggcuaag      840

gaacacauac ggcguaaucg gcagagucgg accuuuuugg uggagaaugu cauaggagaa      900

aucugguccg agcuggagga aggugauaag uaugugguug uggacagugg cgguggcacc      960

guagaccuga caguccauca gauccgguua ccggagggac accuuaagga acuguauaaa     1020

gcaacaggcg gacccuaugg aucuuuagga guagauuaug aguucgaaaa acuucuguau     1080

aaaauauuug gagaggauuu uauugaacaa uucaaaauca aacgcccugc agccuggguu     1140

gacuuaauga uugcguuuga gucucgcaaa agggcggcug ccccagacag aacuaacccg     1200

cugaacauca cccugcccuu cuccuucauu gacuacuaca agaaguuccg cgggcacagu     1260

guggagcacg ccuugcggaa aagcaaugug gauuuuguga agugguccuc gcaggggaug     1320

cugcggauga guccagaugc caugaacgcc cuuuuuaagc cgaccaucga uagcaucauu     1380

gagcaucucc gggaccuguu ucagaagccc gaggugucca ccgucaaguu ccucuuucug     1440

gugggcggcu uugccgaggc gccccugcug cagcaggcgg ugcaggcugc uuuuggggac     1500

cagugccgga ucaucauccc ccaggacgug ggccucacca uccucaaggg ugccguccuc     1560

uuuggccugg accccgcggu caucaaggug cgccggucgc cgcucaccua cgggguaggc     1620

gugcugaacc gcuacgugga gggcaagcac ccgccugaga agcugcuggu gaaggauggc     1680

acucgguggu gcaccgacgu cuuugacaag uucaucucug ccgaccaguc uguggcucug     1740

ggugagcugg ucaagcguag cuacaccccg gccaagcccu cccagcuggu cauugucauc     1800

aacaucuaca gcucugagca cgacaacguc agcuucauca cugaucccgg ggugaagaag     1860

uguggcacgc uccgccugga ucucacaggg accaguggca cugcggugcc cgcccggagg     1920

gagauccaga cccuuaugca guucggggac accgagauca aagccacagc cauugauaua     1980

gccacuucga agagugucaa aguugggauc gacuucuuaa auuacuaa                  2028


<210>  175
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  175
auguuggcug ucccggagau gggccugcag gggcuguaca ucggcuccag cccggagcgg       60

uccccagugc cuagcccacc cggcuccccg aggacccagg aaagcugcgg cauugccccc      120

cucacacccu cgcagucucc aaaacccgag guccgagccc cccagcaggc cuccuucucu      180

gugguggugg ccauugacuu cggcaccacg ucuaguggcu augcuuucag cuuugccagu      240

gacccugagg ccauccacau gaugaggaaa ugggagggcg gagacccggg cguggcccac      300

cagaagaccc cgaccugccu gcugcugacu ccggagggcg ccuuccacag cuuuggcuac      360

accgcccgcg auuacuacca ugaccuggac cccgaagagg cgcgggacug gcucuacuuc      420

gagaaguuca agaugaagau ccacagcgcc acggaucuca ccuugaagac ccagcuagag      480

gcaguaaaug gaaagacgau gcccgcccug gagguguucg cccaugcccu gcgcuucuuc      540

agggagcacg cccuucagga gcugagggag cagagcccau cgcugccaga gaaggacacu      600

gugcgcuggg uguugacggu gccugccauc uggaaacagc cagccaagca guucaugcgg      660

gaggcugccu accuggcugg acuagugucc cgagagaaug cagagcagcu acucaucgcc      720

cuggagcccg aggccgccuc gguauacugc cgcaagcugc gccugcacca gcuccuggac      780

cugaguggcc gggccccagg uggugggcgc cugggugagc gccgcuccau cgacuccagc      840

uuccgucagg cucgggagca gcugcgaagg ucccgccaca gccgcacguu ccugguggag      900

ucaggcguag gagagcugug ggcagagaug caagcaggag accgcuacgu gguggccgac      960

ugcggcggag gcaccgugga ccugacggug caccagcugg agcagcccca uggcacccuc     1020

aaggagcucu acaaggcauc ugggggcccu uauggcgcgg ugggcgugga ccuggccuuc     1080

gagcagcugc ugugccgcau cuucggcgag gacuucaucg ccaccuucaa aaggcaacgg     1140

ccggcagccu ggguagaucu gaccaucgcc uucgaggcuc gcaagcgcac ugcuggccca     1200

caccgugcag gggcgcucaa caucucgcug cccuucuccu ucauugacuu cuaccgcaag     1260

cagcggggcc acaacgugga gaccgcucug cgcaggagca gcgugaacuu cgugaagugg     1320

uccucacagg ggaugcuccg aaugucuugu gaagccauga acgagcucuu ucagcccacc     1380

gucagcggga ucauccagca cauagaggcc cugcuggcac ggccggaggu gcagggugug     1440

aagcugcugu uccuaguggg cggcuucgcc gagucagcgg ugcugcagca cgcggugcag     1500

gcggcgcugg gcgcccgcgg ucugcguguc guggucccgc acgacguggg ccucaccauc     1560

cucaaaggcg cggugcuguu cggccaggcg ccgggcgugg ugcggguccg ccgcucgccg     1620

cucaccuaug gcgugggcgu gcucaaccgc uuugugccug ggcgccaccc gcccgaaaag     1680

cugcugguuc gcgacggccg ccgcuggugc accgacgucu ucgagcgcuu cguggccgcc     1740

gagcagucgg uggcccuggg cgaggaggug cggcgcagcu acugcccggc gcgucccggc     1800

cagcggcgcg uacucaucaa ccuguacugc ugcgcggcag aggaugcgcg cuucaucacc     1860

gaccccggcg ugcgcaaaug cggcgcgcuc agccucgagc uugagcccgc cgacugcggc     1920

caggacaccg ccggcgcgcc ucccggccgc cgcgagaucc gcgccgccau gcaguuuggc     1980

gacaccgaaa uuaaggucac cgccgucgac gucagcacca aucgcuccgu gcgcgcgucc     2040

aucgacuuuc uuuccaacug a                                               2061


<210>  176
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  176
auggccagag agaugacgau cuuaggaucg gcuguuuuga cucuccuguu ggccggcuau       60

uuggcacaac aguauuuacc auugccuacu ccuaaaguga uugguauuga ucuuggcacc      120

accuauuguu cuguuggggu guuuuuuccu ggcacaggaa aaguaaaggu gauuccagau      180

gaaaaugggc auaucagcau acccagcaug gugucuuuua cugacaauga uguauaugug      240

ggauaugaaa gcguagagcu ggcagauuca aauccucaaa acacaauaua ugaugccaaa      300

agauucauag gcaagauuuu uaccgcagaa gaguuggagg cugaaauugg cagauaccca      360

uuuaagguuu uaaacaaaaa uggaaugguu gaguuuucug ugacaaguaa ugagaccauc      420

acaguguccc cagaauaugu uggcucucga cuauuguuga aguuaaagga aauggcagag      480

gcauaucuug gaaugccagu ugccaaugcu gucauuucug uaccagcaga auuugaucua      540

aaacagagaa auucaacaau ugaagcugcu aaccuugcag gacugaagau uuugagggua      600

auaaaugaac ccacagcagc agcuauggcc uauggucucc acaaggcuga cgucuuccac      660

gucuugguga uagacuuggg cggaggaacu cuagaugugu cuuuacugaa uaaacaagga      720

gggauguuuc uaacccgagc aaugucugga aacaauaaac uuggaggaca ggacuucaau      780

cagagauugc uucaguacuu auauaaacag aucuaucaaa cauauggcuu cgugcccucu      840

aggaaagagg aaauccacag auugagacaa gcuguggaaa uggucaaauu aaaucugacu      900

cuucaucaau cugcucaguu gucaguauua cuaacggugg aggagcagga caggaaggaa      960

ccucacagua gugacacuga acugccaaaa gacaaacuuu ccucagcaga ugaccaucgc     1020

gugaacagug gguuuggacg uggccuuucu gauaagaaaa guggagaaag ucagguuuua     1080

uuugaaacag aaauaucacg gaaacucuuu gauacccuua augaagaccu cuuucagaaa     1140

auacugguac ccauucagca aguauugaaa gaaggccacc uggaaaagac ugagauugau     1200

gaggugguuu uaguuggggg cuccacucgu auuccucgga uccgucaagu cauucaagag     1260

uucuuuggaa aagaucccaa cacaucugua gacccugacc uagcaguagu aacgggagug     1320

gcuauccaag cagggauuga uggaggcucu uggccucucc aagucagugc uuuagaaauu     1380

cccaauaagc auuuacaaaa aaccaacuuc aacuga                               1416


<210>  177
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  177
auggcggcca ucggaguuca ccugggcugc accucagccu guguggccgu cuauaaggau       60

ggccgggcug gugugguugc aaaugaugcc ggugaccgag uuacuccagc uguuguugcu      120

uacucagaaa augaagagau uguuggauug gcagcaaaac aaaguagaau aagaaauauu      180

ucaaauacag uaaugaaagu aaagcagauc cugggcagaa gcuccaguga uccacaagcu      240

cagaaauaca ucgcggaaag uaaauguuua gucauugaaa aaaaugggaa auuacgauau      300

gaaauagaua cuggagaaga aacaaaauuu guuaacccag aagauguugc cagacugaua      360

uuuaguaaaa ugaaagaaac ggcacauucu guauugggcu cagaugcaaa ugauguaguu      420

auuacugucc cguuugauuu uggagaaaag caaaaaaaug cucuuggaga agcagcuaga      480

gcugcuggau uuaauguuuu gcgauuaauu cacgaaccgu cugcagcucu ucuugcuuau      540

ggaauuggac aagacucccc uacuggaaaa agcaauauuu ugguguuuaa gcuuggagga      600

acauccuuau cucucagcgu cauggaaguu aacaguggaa uauaucgggu ucuuucaaca      660

aacacugaug auaacaucgg uggugcacau uucacagaaa ccuuagcaca guaucuagcu      720

ucugaguucc aaagauccuu caaacaugau gugagaggaa augcgcgagc caugaugaaa      780

uuaacgaaca gugcugaagu agcgaaacau ucuuugucaa ccuugggaag ugccaacugu      840

uuucuugacu cauuauauga aggucaagau uuugauugca auguguccag agcaagauuu      900

gaacuucuuu guucuccacu uuuuaauaag uguauagaag caaucagagg acucuuagau      960

caaaauggau uuacagcaga ugauaucaac aagguugucc uuuguggagg gucuucucga     1020

aucccaaagc uacagcaacu gauuaaagau cuuuucccag cuguugagcu ucucaauucu     1080

aucccuccug augaagugau cccuauuggu gcagcuauag aagcaggaau ucuuauuggg     1140

aaagaaaacc uguuggugga agacucucuu augauagagu guucagccag agauauuuua     1200

guuaagggug uggacgaauc aggagccagu agauucacag ugcuguuucc aucagggacu     1260

ccuuugccag cucgaagaca acacacauug caagccccug gaagcauauc uucagugugc     1320

cuugaacucu augagucuga ugggaagaac ucugccaaag aggaaaccaa guuugcacag     1380

guuguacucc aggauuuaga uaaaaaagaa aauggauuac gugauauauu agcuguucuu     1440

acuaugaaaa gggauggauc uuuacaugug acaugcacag aucaagaaac uggaaaaugu     1500

gaagcaaucu cuauugagau agcaucuuag                                      1530


<210>  178
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  178
augucggugg ugggguugga cgugggcucg cagagcugcu acaucgcggu agcccgggcc       60

gggggcaucg agaccaucgc caaugaguuc agcgaccggu gcaccccguc agucauauca      120

uuuggaucaa aaaauagaac aaucggaguu gcagccaaaa aucagcaaau cacucaugca      180

aacaauacgg ugucuaacuu caaaagauuu cauggccgag cauucaauga ccccuucauu      240

caaaaggaga aggaaaacuu gaguuacgau uugguuccau ugaaaaaugg uggaguugga      300

auaaagguaa uguacauggg ugaagaacau cuauuuagug uggagcagau aacagccaug      360

uuguugacua agcugaagga aacugcugaa aacagccuca agaaaccagu aacagauugu      420

guuauuucag uccccuccuu cuuuacagau gcugagaggc gaucuguguu agaugcugca      480

cagauuguug gccuaaacug uuuaagacuu augaaugaca ugacagcugu ugcuuugaau      540

uacggaauuu auaagcagga ucucccaagc cuggaugaga aaccucggau agugguuuuu      600

guugauaugg gacauucagc uuuucaagug ucugcuugug cuuuuaacaa gggaaaauug      660

aagguacugg gaacagcuuu ugauccuuuc uuaggaggaa aaaacuucga ugaaaaguua      720

guggaacauu uuugugcaga auuuaaaacu aaguacaagu uggaugcaaa auccaaaaua      780

cgagcacucc uacgucugua ucaggaaugu gaaaaacuga aaaagcuaau gagcucuaac      840

agcacagacc uuccacugaa uaucgaaugc uuuaugaaug auaaagaugu uuccggaaag      900

augaacaggu cacaauuuga agaacucugu gcugaacuuc ugcaaaagau agaaguaccc      960

cuuuauucac uguuggaaca aacucaucuc aaaguagaag augugagugc aguugagauu     1020

guuggaggcg cuacacgaau uccagcugug aaggaaagaa uugccaaauu cuuuggaaaa     1080

gauauuagca caacacucaa ugcagaugaa gcaguagcca gaggaugugc auuacagugu     1140

gcaauacuuu ccccggcauu uaaaguuaga gaauuuuccg ucacagaugc aguuccuuuu     1200

ccaauaucuc ugaucuggaa ccaugauuca gaagauacug aagguguuca ugaagucuuu     1260

agucgaaacc augcugcucc uuucuccaaa guucucaccu uucugagaag ggggccuuuu     1320

gagcuagaag cuuucuauuc ugauccccaa ggaguuccau auccagaagc aaaaauaggc     1380

cgcuuuguag uucagaaugu uucugcacag aaagauggag aaaaaucuag aguaaaaguc     1440

aaagugcgag ucaacaccca uggcauuuuc accaucucua cggcaucuau gguggagaaa     1500

gucccaacug aggagaauga aaugucuucu gaagcugaca uggagugucu gaaucagaga     1560

ccaccagaaa acccagacac ugauaaaaau guccagcaag acaacaguga agcuggaaca     1620

cagccccagg uacaaacuga ugcucaacaa accucacagu cucccccuuc accugaacuu     1680

accucagaag aaaacaaaau cccagaugcu gacaaagcaa augaaaaaaa aguugaccag     1740

ccuccagaag cuaaaaagcc caaaauaaag guggugaaug uugagcugcc uauugaagcc     1800

aacuuggucu ggcaguuagg gaaagaccuu cuuaacaugu auauugagac agaggguaag     1860

augauaaugc aagauaaauu ggaaaaagaa aggaaugaug cuaaaaaugc aguugaggaa     1920

uauguguaug aguucagaga caagcugugu ggaccauaug aaaaauuuau augugagcag     1980

gaucaucaaa auuuuuugag acuccucaca gaaacugaag acuggcugua ugaagaagga     2040

gaggaccaag cuaaacaagc auauguugac aaguuggaag aauuaaugaa aauuggcacu     2100

ccaguuaaag uucgguuuca ggaagcugaa gaacggccaa aaauguuuga agaacuagga     2160

cagaggcugc agcauuaugc caagauagca gcugacuuca gaaauaagga ugagaaauac     2220

aaccauauug augagucuga aaugaaaaaa guggagaagu cuguuaauga agugauggaa     2280

uggaugaaua augucaugaa ugcucaggcu aaaaagaguc uugaucagga uccaguugua     2340

cgugcucagg aaauuaaaac aaaaaucaag gaauugaaca acacauguga acccguugua     2400

acacaaccga aaccaaaaau ugaaucaccc aaacuggaaa gaacuccaaa uggcccaaau     2460

auugauaaaa aggaagaaga uuuagaagac aaaaacaauu uuggugcuga accuccacau     2520

cagaauggug aauguuaccc uaaugagaaa aauucuguua auauggacuu ggacuag        2577


<210>  179
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  179
auggcagaca aaguuaggag gcagaggccg aggaggcgag ucuguugggc cuugguggcu       60

gugcucuugg cagaccuguu ggcacugagu gauacacugg cagugauguc uguggaccug      120

ggcagugagu ccaugaaggu ggccauuguc aaaccuggag ugcccaugga aauugucuug      180

aauaaggaau cucggaggaa aacaccggug aucgugaccc ugaaagaaaa ugaaagauuc      240

uuuggagaca gugcagcaag cauggcgauu aagaauccaa aggcuacgcu acguuacuuc      300

cagcaccucc uggggaagca ggcagauaac ccccauguag cucuuuacca ggcccgcuuc      360

ccggagcacg agcugacuuu cgacccacag aggcagacug ugcacuuuca gaucagcucg      420

cagcugcagu ucucaccuga ggaaguguug ggcaugguuc ucaauuauuc ucguucucua      480

gcugaagauu uugcagagca gcccaucaag gaugcaguga ucaccgugcc agucuucuuc      540

aaccaggccg agcgccgagc ugugcugcag gcugcucgua uggcuggccu caaagugcug      600

cagcucauca augacaacac cgccacugcc cucagcuaug gugucuuccg ccggaaagau      660

auuaacacca cugcccagaa uaucauguuc uaugacaugg gcucaggcag caccguaugc      720

accauuguga ccuaccagau ggugaagacu aaggaagcug ggaugcagcc acagcugcag      780

auccggggag uaggauuuga ccguacccug gggggccugg agauggagcu ccggcuucga      840

gaacgccugg cugggcuuuu caaugagcag cgcaaggguc agagagcaaa ggaugugcgg      900

gagaacccgc gugccauggc caagcugcug cgugaggcua aucggcucaa aaccguccuc      960

agugccaacg cugaccacau ggcacagauu gaaggccuga uggaugaugu ggacuucaag     1020

gcaaaaguga cucgugugga auuugaggag uugugugcag acuuguuuga gcgggugccu     1080

gggccuguac agcaggcccu ccagagugcc gaaaugaguc uggaugagau ugagcaggug     1140

auccuggugg guggggccac ucgggucccc agaguucagg aggugcugcu gaaggccgug     1200

ggcaaggagg agcuggggaa gaacaucaau gcagaugaag cagccgccau gggggcagug     1260

uaccaggcag cugcgcucag caaagccuuu aaagugaagc cauuugucgu ccgagaugca     1320

guggucuacc ccauccuggu ggaguucacg agggaggugg aggaggagcc ugggauucac     1380

agccugaagc acaauaaacg gguacucuuc ucucggaugg ggcccuaccc ucaacgcaaa     1440

gucaucaccu uuaaccgcua cagccaugau uucaacuucc acaucaacua cggcgaccug     1500

ggcuuccugg ggccugaaga ucuucgggua uuuggcuccc agaaucugac cacagugaag     1560

cuaaaagggg ugggugacag cuucaagaag uauccugacu acgaguccaa gggcaucaag     1620

gcucacuuca accuggauga gaguggcgug cucagucuag acagggugga gucuguauuu     1680

gagacacugg uagaggacag cgcagaagag gaaucuacuc ucaccaaacu uggcaacacc     1740

auuuccagcc uguuuggagg cgguaccaca ccagaugcca aggagaaugg uacugauacu     1800

guccaggagg aagaggagag cccugcagag gggagcaagg acgagccugg ggagcaggug     1860

gagcucaagg aggaagcuga ggccccagug gaggauggcu cucagccccc acccccugaa     1920

ccuaagggag augcaacccc ugagggagaa aaggccacag aaaaagaaaa uggggacaag     1980

ucugaggccc agaaaccaag ugagaaggca gaggcagggc cugagggcgu cgcuccagcc     2040

ccagagggag agaagaagca gaagcccgcc aggaagcggc gaaugguaga ggagaucggg     2100

guggagcugg uuguucugga ccugccugac uugccagagg auaagcuggc ucagucggug     2160

cagaaacuuc aggacuugac acuccgagac cuggagaagc aggaacggga aaaagcugcc     2220

aacagcuugg aagcauucau auuugagacc caggacaagc uguaccagcc cgaguaccag     2280

gaagugucca cagaggagca gcgugaggag aucucuggga agcucagcgc cgcauccacc     2340

uggcuggagg augagggugu uggagccacc acagugaugu ugaaggagaa gcuggcugag     2400

cugaggaagc ugugccaagg gcuguuuuuu cggguagagg agcgcaagaa guggcccgaa     2460

cggcugucug cccucgauaa ucuccucaac cauuccagca uguuccucaa gggggcccgg     2520

cucaucccag agauggacca gaucuucacu gagguggaga ugacaacguu agagaaaguc     2580

aucaaugaga ccugggccug gaagaaugca acucuggccg agcaggcuaa gcugcccgcc     2640

acagagaagc cuguguugcu cucaaaagac auugaagcua agaugauggc ccuggaccga     2700

gaggugcagu aucugcucaa uaaggccaag uuuaccaagc cccggccccg gccuaaggac     2760

aagaauggga cccgggcaga gccaccccuc aaugccagug ccagugacca gggggagaag     2820

gucaucccuc cagcaggcca gacugaagau gcagagccca uuucagaacc ugagaaagua     2880

gagacuggau ccgagccagg agacacugag ccuuuggagu uaggaggucc uggagcagaa     2940

ccugaacaga aagaacaauc gacaggacag aagcggccuu ugaagaacga cgaacuauaa     3000


<210>  180
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  180
augccugagg aaacccagac ccaagaccaa ccgauggagg aggaggaggu ugagacguuc       60

gccuuucagg cagaaauugc ccaguugaug ucauugauca ucaauacuuu cuacucgaac      120

aaagagaucu uucugagaga gcucauuuca aauucaucag augcauugga caaaauccgg      180

uaugaaagcu ugacagaucc caguaaauua gacucuggga aagagcugca uauuaaccuu      240

auaccgaaca aacaagaucg aacucucacu auuguggaua cuggaauugg aaugaccaag      300

gcugacuuga ucaauaaccu ugguacuauc gccaagucug ggaccaaagc guucauggaa      360

gcuuugcagg cuggugcaga uaucucuaug auuggccagu ucgguguugg uuuuuauucu      420

gcuuauuugg uugcugagaa aguaacugug aucaccaaac auaacgauga ugagcaguac      480

gcuugggagu ccucagcagg gggaucauuc acagugagga cagacacagg ugaaccuaug      540

ggucguggaa caaaaguuau ccuacaccug aaagaagacc aaacugagua cuuggaggaa      600

cgaagaauaa aggagauugu gaagaaacau ucucaguuua uuggauaucc cauuacucuu      660

uuuguggaga aggaacguga uaaagaagua agcgaugaug aggcugaaga aaaggaagac      720

aaagaagaag aaaaagaaaa agaagagaaa gagucggaag acaaaccuga aauugaagau      780

guugguucug augaggaaga agaaaagaag gauggugaca agaagaagaa gaagaagauu      840

aaggaaaagu acaucgauca agaagagcuc aacaaaacaa agcccaucug gaccagaaau      900

cccgacgaua uuacuaauga ggaguacgga gaauucuaua agagcuugac caaugacugg      960

gaagaucacu uggcagugaa gcauuuuuca guugaaggac aguuggaauu cagagcccuu     1020

cuauuugucc cacgacgugc uccuuuugau cuguuugaaa acagaaagaa aaagaacaac     1080

aucaaauugu auguacgcag aguuuucauc auggauaacu gugaggagcu aaucccugaa     1140

uaucugaacu ucauuagagg ggugguagac ucggaggauc ucccucuaaa cauaucccgu     1200

gagauguugc aacaaagcaa aauuuugaaa guuaucagga agaauuuggu caaaaaaugc     1260

uuagaacucu uuacugaacu ggcggaagau aaagagaacu acaagaaauu cuaugagcag     1320

uucucuaaaa acauaaagcu uggaauacac gaagacucuc aaaaucggaa gaagcuuuca     1380

gagcuguuaa gguacuacac aucugccucu ggugaugaga ugguuucucu caaggacuac     1440

ugcaccagaa ugaaggagaa ccagaaacau aucuauuaua ucacagguga gaccaaggac     1500

cagguagcua acucagccuu uguggaacgu cuucggaaac auggcuuaga agugaucuau     1560

augauugagc ccauugauga guacuguguc caacagcuga aggaauuuga ggggaagacu     1620

uuagugucag ucaccaaaga aggccuggaa cuuccagagg augaagaaga gaaaaagaag     1680

caggaagaga aaaaaacaaa guuugagaac cucugcaaaa ucaugaaaga cauauuggag     1740

aaaaaaguug aaaagguggu ugugucaaac cgauugguga caucuccaug cuguauuguc     1800

acaagcacau auggcuggac agcaaacaug gagagaauca ugaaagcuca agcccuaaga     1860

gacaacucaa caauggguua cauggcagca aagaaacacc uggagauaaa cccugaccau     1920

uccauuauug agaccuuaag gcaaaaggca gaggcugaua agaacgacaa gucugugaag     1980

gaucugguca ucuugcuuua ugaaacugcg cuccugucuu cuggcuucag ucuggaagau     2040

ccccagacac augcuaacag gaucuacagg augaucaaac uuggucuggg uauugaugaa     2100

gaugacccua cugcugauga uaccagugcu gcuguaacug aagaaaugcc accccuugaa     2160

ggagaugacg acacaucacg cauggaagaa guagacuaa                            2199


<210>  181
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  181
auggauucca guaaauuaga cucugggaaa gggcugcaua uuaaccuugu accaaacaaa       60

caaaaucaaa cccucacuau uguggacacu agaauuggaa ugaccaagac ugacuugauc      120

aauaaccucg guacugucac caagucuggg accaaagcau ucauggaagc uuugcaggcu      180

gaugcagaua ucucuaugau uggccauuuc gggguugguu uuuauucugc uuauuugguu      240

gccaagaaag uaacugugau cagcaaacau aacaaugaug agcaguacac cugggagucc      300

ucagcagggg gaucauucac agugaggaca gacgaguga                             339


<210>  182
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  182
augccugagg aagugcacca uggagaggag gagguggaga cuuuugccuu ucaggcagaa       60

auugcccaac ucaugucccu caucaucaau accuucuauu ccaacaagga gauuuuccuu      120

cgggaguuga ucucuaaugc uucugaugcc uuggacaaga uucgcuauga gagccugaca      180

gacccuucga aguuggacag ugguaaagag cugaaaauug acaucauccc caacccucag      240

gaacguaccc ugacuuuggu agacacaggc auuggcauga ccaaagcuga ucucauaaau      300

aauuugggaa ccauugccaa gucugguacu aaagcauuca uggaggcucu ucaggcuggu      360

gcagacaucu ccaugauugg gcaguuuggu guuggcuuuu auucugccua cuugguggca      420

gagaaagugg uugugaucac aaagcacaac gaugaugaac aguaugcuug ggagucuucu      480

gcuggagguu ccuucacugu gcgugcugac cauggugagc ccauuggcag ggguaccaaa      540

gugauccucc aucuuaaaga agaucagaca gaguaccuag aagagaggcg ggucaaagaa      600

guagugaaga agcauucuca guucauaggc uaucccauca cccuuuauuu ggagaaggaa      660

cgagagaagg aaauuaguga ugaugaggca gaggaagaga aaggugagaa agaagaggaa      720

gauaaagaug augaagaaaa acccaagauc gaagaugugg guucagauga ggaggaugac      780

agcgguaagg auaagaagaa gaaaacuaag aagaucaaag agaaauacau ugaucaggaa      840

gaacuaaaca agaccaagcc uauuuggacc agaaacccug augacaucac ccaagaggag      900

uauggagaau ucuacaagag ccucacuaau gacugggaag accacuuggc agucaagcac      960

uuuucuguag aaggucaguu ggaauucagg gcauugcuau uuauuccucg ucgggcuccc     1020

uuugaccuuu uugagaacaa gaagaaaaag aacaacauca aacucuaugu ccgccgugug     1080

uucaucaugg acagcuguga ugaguugaua ccagaguauc ucaauuuuau ccguggugug     1140

guugacucug aggaucugcc ccugaacauc ucccgagaaa ugcuccagca gagcaaaauc     1200

uugaaaguca uucgcaaaaa cauuguuaag aagugccuug agcucuucuc ugagcuggca     1260

gaagacaagg agaauuacaa gaaauucuau gaggcauucu cuaaaaaucu caagcuugga     1320

auccacgaag acuccacuaa ccgccgccgc cugucugagc ugcugcgcua ucauaccucc     1380

cagucuggag augagaugac aucucuguca gaguauguuu cucgcaugaa ggagacacag     1440

aaguccaucu auuacaucac uggugagagc aaagagcagg uggccaacuc agcuuuugug     1500

gagcgagugc ggaaacgggg cuucgaggug guauauauga ccgagcccau ugacgaguac     1560

ugugugcagc agcucaagga auuugauggg aagagccugg ucucaguuac caaggagggu     1620

cuggagcugc cugaggauga ggaggagaag aagaagaugg aagagagcaa ggcaaaguuu     1680

gagaaccucu gcaagcucau gaaagaaauc uuagauaaga agguugagaa ggugacaauc     1740

uccaauagac uugugucuuc accuugcugc auugugacca gcaccuacgg cuggacagcc     1800

aauauggagc ggaucaugaa agcccaggca cuucgggaca acuccaccau gggcuauaug     1860

auggccaaaa agcaccugga gaucaacccu gaccacccca uuguggagac gcugcggcag     1920

aaggcugagg ccgacaagaa ugauaaggca guuaaggacc ugguggugcu gcuguuugaa     1980

accgcccugc uaucuucugg cuuuucccuu gaggaucccc agacccacuc caaccgcauc     2040

uaucgcauga ucaagcuagg ucuagguauu gaugaagaug aaguggcagc agaggaaccc     2100

aaugcugcag uuccugauga gauccccccu cucgagggcg augaggaugc gucucgcaug     2160

gaagaagucg auuag                                                      2175


<210>  183
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  183
augagggccc ugugggugcu gggccucugc ugcguccugc ugaccuucgg gucggucaga       60

gcugacgaug aaguugaugu ggaugguaca guagaagagg aucuggguaa aaguagagaa      120

ggaucaagga cggaugauga aguaguacag agagaggaag aagcuauuca guuggaugga      180

uuaaaugcau cacaaauaag agaacuuaga gagaagucgg aaaaguuugc cuuccaagcc      240

gaaguuaaca gaaugaugaa acuuaucauc aauucauugu auaaaaauaa agagauuuuc      300

cugagagaac ugauuucaaa ugcuucugau gcuuuagaua agauaaggcu aauaucacug      360

acugaugaaa augcucuuuc uggaaaugag gaacuaacag ucaaaauuaa gugugauaag      420

gagaagaacc ugcugcaugu cacagacacc gguguaggaa ugaccagaga agaguugguu      480

aaaaaccuug guaccauagc caaaucuggg acaagcgagu uuuuaaacaa aaugacugaa      540

gcacaggaag auggccaguc aacuucugaa uugauuggcc aguuuggugu cgguuucuau      600

uccgccuucc uuguagcaga uaagguuauu gucacuucaa aacacaacaa cgauacccag      660

cacaucuggg agucugacuc caaugaauuu ucuguaauug cugacccaag aggaaacacu      720

cuaggacggg gaacgacaau uacccuuguc uuaaaagaag aagcaucuga uuaccuugaa      780

uuggauacaa uuaaaaaucu cgucaaaaaa uauucacagu ucauaaacuu uccuauuuau      840

guauggagca gcaagacuga aacuguugag gagcccaugg aggaagaaga agcagccaaa      900

gaagagaaag aagaaucuga ugaugaagcu gcaguagagg aagaagaaga agaaaagaaa      960

ccaaagacua aaaaaguuga aaaaacuguc ugggacuggg aacuuaugaa ugauaucaaa     1020

ccaauauggc agagaccauc aaaagaagua gaagaagaug aauacaaagc uuucuacaaa     1080

ucauuuucaa aggaaaguga ugaccccaug gcuuauauuc acuuuacugc ugaaggggaa     1140

guuaccuuca aaucaauuuu auuuguaccc acaucugcuc cacguggucu guuugacgaa     1200

uauggaucua aaaagagcga uuacauuaag cucuaugugc gccguguauu caucacagac     1260

gacuuccaug auaugaugcc uaaauaccuc aauuuuguca aggguguggu ggacucagau     1320

gaucuccccu ugaauguuuc ccgcgagacu cuucagcaac auaaacugcu uaaggugauu     1380

aggaagaagc uuguucguaa aacgcuggac augaucaaga agauugcuga ugauaaauac     1440

aaugauacuu uuuggaaaga auuugguacc aacaucaagc uuggugugau ugaagaccac     1500

ucgaaucgaa cacgucuugc uaaacuucuu agguuccagu cuucucauca uccaacugac     1560

auuacuagcc uagaccagua uguggaaaga augaaggaaa aacaagacaa aaucuacuuc     1620

auggcugggu ccagcagaaa agaggcugaa ucuucuccau uuguugagcg acuucugaaa     1680

aagggcuaug aaguuauuua ccucacagaa ccuguggaug aauacuguau ucaggcccuu     1740

cccgaauuug augggaagag guuccagaau guugccaagg aaggagugaa guucgaugaa     1800

agugagaaaa cuaaggagag ucgugaagca guugagaaag aauuugagcc ucugcugaau     1860

uggaugaaag auaaagcccu uaaggacaag auugaaaagg cugugguguc ucagcgccug     1920

acagaaucuc cgugugcuuu gguggccagc caguacggau ggucuggcaa cauggagaga     1980

aucaugaaag cacaagcgua ccaaacgggc aaggacaucu cuacaaauua cuaugcgagu     2040

cagaagaaaa cauuugaaau uaaucccaga cacccgcuga ucagagacau gcuucgacga     2100

auuaaggaag augaagauga uaaaacaguu uuggaucuug cugugguuuu guuugaaaca     2160

gcaacgcuuc ggucagggua ucuuuuacca gacacuaaag cauauggaga uagaauagaa     2220

agaaugcuuc gccucaguuu gaacauugac ccugaugcaa agguggaaga agagcccgaa     2280

gaagaaccug aagagacagc agaagacaca acagaagaca cagagcaaga cgaagaugaa     2340

gaaauggaug ugggaacaga ugaagaagaa gaaacagcaa aggaaucuac agcugaaaaa     2400

gaugaauugu aa                                                         2412


<210>  184
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  184
auggcgcgcg agcugcgggc gcugcugcug uggggccgcc gccugcggcc uuugcugcgg       60

gcgccggcgc uggcggccgu gccgggagga aaaccaauuc uguguccucg gaggaccaca      120

gcccaguugg gccccaggcg aaacccagcc uggagcuugc aggcaggacg acuguucagc      180

acgcagaccg ccgaggacaa ggaggaaccc cugcacucga uuaucagcag cacagagagc      240

gugcaggguu ccacuuccaa acaugaguuc caggccgaga caaagaagcu uuuggacauu      300

guugcccggu cccuguacuc agaaaaagag guguuuauac gggagcugau cuccaaugcc      360

agcgaugccu uggaaaaacu gcgucacaaa cuggugucug acggccaagc acugccagaa      420

auggagauuc acuugcagac caaugccgag aaaggcacca ucaccaucca ggauacuggu      480

aucgggauga cacaggaaga gcuggugucc aaccugggga cgauugccag aucgggguca      540

aaggccuucc uggaugcucu gcagaaccag gcugaggcca gcagcaagau caucggccag      600

uuuggagugg guuucuacuc agcuuucaug guggcugaca gaguggaggu cuauucccgc      660

ucggcagccc cggggagccu ggguuaccag uggcuuucag augguucugg aguguuugaa      720

aucgccgaag cuucgggagu uagaaccggg acaaaaauca ucauccaccu gaaauccgac      780

ugcaaggagu uuuccagcga ggcccgggug cgagaugugg uaacgaagua cagcaacuuc      840

gucagcuucc ccuuguacuu gaauggaagg cggaugaaca ccuugcaggc caucuggaug      900

auggacccca aggauguccg ugaguggcaa caugaggagu ucuaccgcua cgucgcgcag      960

gcucacgaca agccccgcua cacccugcac uauaagacgg acgcaccgcu caacauccgc     1020

agcaucuucu acgugcccga caugaaaccg uccauguuug augugagccg ggagcugggc     1080

uccagcguug cacuguacag ccgcaaaguc cucauccaga ccaaggccac ggacauccug     1140

cccaaguggc ugcgcuucau ccgaggugug guggacagug aggacauucc ccugaaccuc     1200

agccgggagc ugcugcagga gagcgcacuc aucaggaaac uccgggacgu uuuacagcag     1260

aggcugauca aauucuucau ugaccagagu aaaaaagaug cugagaagua ugcaaaguuu     1320

uuugaagauu acggccuguu caugcgggag ggcauuguga ccgccaccga gcaggagguc     1380

aaggaggaca uagcaaagcu gcugcgcuac gaguccucgg cgcugcccuc cgggcagcua     1440

accagccucu cagaauacgc cagccgcaug cgggccggca cccgcaacau cuacuaccug     1500

ugcgccccca accgucaccu ggcagagcac ucacccuacu augaggccau gaagaagaaa     1560

gacacagagg uucucuucug cuuugagcag uuugaugagc ucacccugcu gcaccuucgu     1620

gaguuugaca agaagaagcu gaucucugug gagacggaca uagucgugga ucacuacaag     1680

gaggagaagu uugaggacag guccccagcc gccgagugcc uaucagagaa ggagacggag     1740

gagcucaugg ccuggaugag aaaugugcug gggucgcgug ucaccaacgu gaaggugacc     1800

cuccgacugg acacccaccc ugccaugguc accgugcugg agaugggggc ugcccgccac     1860

uuccugcgca ugcagcagcu ggccaagacc caggaggagc gcgcacagcu ccugcagccc     1920

acgcuggaga ucaaccccag gcacgcgcuc aucaagaagc ugaaucagcu gcgcgcaagc     1980

gagccuggcc uggcucagcu gcugguggau cagauauacg agaacgccau gauugcugcu     2040

ggacuuguug acgacccuag ggccauggug ggccgcuuga augagcugcu ugucaaggcc     2100

cuggagcgac acuga                                                      2115


<210>  185
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  185
augggaaaaa ucagcagucu uccaacccaa uuauuuaagu gcugcuuuug ugauuucuug       60

aaggugaaga ugcacaccau guccuccucg caucucuucu accuggcgcu gugccugcuc      120

accuucacca gcucugccac ggcuggaccg gagacgcucu gcggggcuga gcugguggau      180

gcucuucagu ucgugugugg agacaggggc uuuuauuuca acaagcccac aggguauggc      240

uccagcaguc ggagggcgcc ucagacaggc aucguggaug agugcugcuu ccggagcugu      300

gaucuaagga ggcuggagau guauugcgca ccccucaagc cugccaaguc agcucgcucu      360

guccgugccc agcgccacac cgacaugccc aagacccaga aggaaguaca uuugaagaac      420

gcaaguagag ggagugcagg aaacaagaac uacaggaugu ag                         462


<210>  186
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  186
augggaaucc caauggggaa gucgaugcug gugcuucuca ccuucuuggc cuucgccucg       60

ugcugcauug cugcuuaccg ccccagugag acccugugcg gcggggagcu gguggacacc      120

cuccaguucg ucugugggga ccgcggcuuc uacuucagca ggcccgcaag ccgugugagc      180

cgucgcagcc guggcaucgu ugaggagugc uguuuccgca gcugugaccu ggcccuccug      240

gagacguacu gugcuacccc cgccaagucc gagagggacg ugucgacccc uccgaccgug      300

cuuccggaca acuuccccag auaccccgug ggcaaguucu uccaauauga caccuggaag      360

caguccaccc agcgccugcg caggggccug ccugcccucc ugcgugcccg ccggggucac      420

gugcucgcca aggagcucga ggcguucagg gaggccaaac gucaccgucc ccugauugcu      480

cuacccaccc aagaccccgc ccacgggggc gcccccccag agauggccag caaucggaag      540

uga                                                                    543


<210>  187
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  187
augaacuccu ucuccacaag cgccuucggu ccaguugccu ucucccuggg gcugcuccug       60

guguugccug cugccuuccc ugccccagua cccccaggag aagauuccaa agauguagcc      120

gccccacaca gacagccacu caccucuuca gaacgaauug acaaacaaau ucgguacauc      180

cucgacggca ucucagcccu gagaaaggag acauguaaca agaguaacau gugugaaagc      240

agcaaagagg cacuggcaga aaacaaccug aaccuuccaa agauggcuga aaaagaugga      300

ugcuuccaau cuggauucaa ugaggagacu ugccugguga aaaucaucac uggucuuuug      360

gaguuugagg uauaccuaga guaccuccag aacagauuug agaguaguga ggaacaagcc      420

agagcugugc agaugaguac aaaaguccug auccaguucc ugcagaaaaa ggcaaagaau      480

cuagaugcaa uaaccacccc ugacccaacc acaaaugcca gccugcugac gaagcugcag      540

gcacagaacc aguggcugca ggacaugaca acucaucuca uucugcgcag cuuuaaggag      600

uuccugcagu ccagccugag ggcucuucgg caaauguag                             639


<210>  188
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  188
augcccuugc uuuggcugag aggauuucug uuggcaaguu gcuggauuau agugaggagu       60

ucccccaccc caggauccga ggggcacagc gcggcccccg acuguccguc cugugcgcug      120

gccgcccucc caaaggaugu acccaacucu cagccagaga ugguggaggc cgucaagaag      180

cacauuuuaa acaugcugca cuugaagaag agacccgaug ucacccagcc gguacccaag      240

gcggcgcuuc ugaacgcgau cagaaagcuu caugugggca aagucgggga gaacggguau      300

guggagauag aggaugacau uggaaggagg gcagaaauga augaacuuau ggagcagacc      360

ucggagauca ucacguuugc cgagucagga acagccagga agacgcugca cuucgagauu      420

uccaaggaag gcagugaccu gucaguggug gagcgugcag aagucuggcu cuuccuaaaa      480

guccccaagg ccaacaggac caggaccaaa gucaccaucc gccucuucca gcagcagaag      540

cacccgcagg gcagcuugga cacaggggaa gaggccgagg aagugggcuu aaagggggag      600

aggagugaac uguugcucuc ugaaaaagua guagacgcuc ggaagagcac cuggcauguc      660

uucccugucu ccagcagcau ccagcgguug cuggaccagg gcaagagcuc ccuggacguu      720

cggauugccu gugagcagug ccaggagagu ggcgccagcu ugguucuccu gggcaagaag      780

aagaagaaag aagaggaggg ggaagggaaa aagaagggcg gaggugaagg uggggcagga      840

gcagaugagg aaaaggagca gucgcacaga ccuuuccuca ugcugcaggc ccggcagucu      900

gaagaccacc cucaucgccg gcgucggcgg ggcuuggagu gugauggcaa ggucaacauc      960

ugcuguaaga aacaguucuu ugucaguuuc aaggacaucg gcuggaauga cuggaucauu     1020

gcucccucug gcuaucaugc caacuacugc gagggugagu gcccgagcca uauagcaggc     1080

acguccgggu ccucacuguc cuuccacuca acagucauca accacuaccg caugcggggc     1140

cauagccccu uugccaaccu caaaucgugc ugugugccca ccaagcugag acccaugucc     1200

auguuguacu augaugaugg ucaaaacauc aucaaaaagg acauucagaa caugaucgug     1260

gaggagugug ggugcucaua g                                               1281


<210>  189
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  189
auggacgggc ugcccggucg ggcgcugggg gccgccugcc uucugcugcu ggcggccggc       60

uggcuggggc cugaggccug gggcucaccc acgcccccgc cgacgccugc cgcgccgccg      120

ccacccccgc cacccggauc cccggguggc ucgcaggaca ccuguacguc gugcggcggc      180

uuccggcggc cagaggagcu cggccgagug gacggcgacu uccuggaggc ggugaagcgg      240

cacaucuuga gccgccugca gaugcggggc cggcccaaca ucacgcacgc cgugccuaag      300

gccgccaugg ucacggcccu gcgcaagcug cacgcgggca aggugcgcga ggacggccgc      360

guggagaucc cgcaccucga cggccacgcc agcccgggcg ccgacggcca ggagcgcguu      420

uccgaaauca ucagcuucgc cgagacagau ggccucgccu ccucccgggu ccgccuauac      480

uucuucaucu ccaacgaagg caaccagaac cuguuugugg uccaggccag ccuguggcuu      540

uaccugaaac uccugcccua cguccuggag aagggcagcc ggcggaaggu gcgggucaaa      600

guguacuucc aggagcaggg ccacggugac agguggaaca ugguggagaa gaggguggac      660

cucaagcgca gcggcuggca uaccuuccca cucacggagg ccauccaggc cuuguuugag      720

cggggcgagc ggcgacucaa ccuagacgug cagugugaca gcugccagga gcuggccgug      780

gugccggugu ucguggaccc aggcgaagag ucgcaccggc ccuuuguggu ggugcaggcu      840

cggcugggcg acagcaggca ccgcauucgc aagcgaggcc uggagugcga uggccggacc      900

aaccucuguu gcaggcaaca guucuucauu gacuuccgcc ucaucggcug gaacgacugg      960

aucauagcac ccaccggcua cuacgggaac uacugugagg gcagcugccc agccuaccug     1020

gcaggggucc ccggcucugc cuccuccuuc cacacggcug uggugaacca guaccgcaug     1080

cggggucuga accccggcac ggugaacucc ugcugcauuc ccaccaagcu gagcaccaug     1140

uccaugcugu acuucgauga ugaguacaac aucgucaagc gggacgugcc caacaugauu     1200

guggaggagu gcggcugcgc cuga                                            1224


<210>  190
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  190
auggcucuca gaguccuucu guuaacagcc uugaccuuau gucauggguu caacuuggac       60

acugaaaacg caaugaccuu ccaagagaac gcaaggggcu ucgggcagag cgugguccag      120

cuucagggau ccaggguggu gguuggagcc ccccaggaga uaguggcugc caaccaaagg      180

ggcagccucu accagugcga cuacagcaca ggcucaugcg agcccauccg ccugcagguc      240

cccguggagg ccgugaacau gucccugggc cugucccugg cagccaccac cagccccccu      300

cagcugcugg ccuguggucc caccgugcac cagacuugca gugagaacac guaugugaaa      360

gggcucugcu uccuguuugg auccaaccua cggcagcagc cccagaaguu cccagaggcc      420

cuccgagggu guccucaaga ggauagugac auugccuucu ugauugaugg cucugguagc      480

aucaucccac augacuuucg gcggaugaag gaguuugucu caacugugau ggagcaauua      540

aaaaagucca aaaccuuguu cucuuugaug caguacucug aagaauuccg gauucacuuu      600

accuucaaag aguuccagaa caacccuaac ccaagaucac uggugaagcc aauaacgcag      660

cugcuugggc ggacacacac ggccacgggc auccgcaaag ugguacgaga gcuguuuaac      720

aucaccaacg gagcccgaaa gaaugccuuu aagauccuag uugucaucac ggauggagaa      780

aaguuuggcg aucccuuggg auaugaggau gucaucccug aggcagacag agagggaguc      840

auucgcuacg ucauuggggu gggagaugcc uuccgcagug agaaaucccg ccaagagcuu      900

aauaccaucg cauccaagcc gccucgugau cacguguucc aggugaauaa cuuugaggcu      960

cugaagacca uucagaacca gcuucgggag aagaucuuug cgaucgaggg uacucagaca     1020

ggaaguagca gcuccuuuga gcaugagaug ucucaggaag gcuucagcgc ugccaucacc     1080

ucuaauggcc ccuugcugag cacugugggg agcuaugacu gggcuggugg agucuuucua     1140

uauacaucaa aggagaaaag caccuucauc aacaugacca gaguggauuc agacaugaau     1200

gaugcuuacu uggguuaugc ugccgccauc aucuuacgga accgggugca aagccugguu     1260

cugggggcac cucgauauca gcacaucggc cugguagcga uguucaggca gaacacuggc     1320

augugggagu ccaacgcuaa ugucaagggc acccagaucg gcgccuacuu cggggccucc     1380

cucugcuccg uggacgugga cagcaacggc agcaccgacc ugguccucau cggggccccc     1440

cauuacuacg agcagacccg agggggccag guguccgugu gccccuugcc cagggggagg     1500

gcucgguggc agugugaugc uguucucuac ggggagcagg gccaacccug gggccgcuuu     1560

ggggcagccc uaacagugcu gggggacgua aauggggaca agcugacgga cguggccauu     1620

ggggccccag gagaggagga caaccggggu gcuguuuacc uguuucacgg aaccucagga     1680

ucuggcauca gccccuccca uagccagcgg auagcaggcu ccaagcucuc ucccaggcuc     1740

caguauuuug gucagucacu gagugggggc caggaccuca caauggaugg acugguagac     1800

cugacuguag gagcccaggg gcacgugcug cugcucaggu cccagccagu acugagaguc     1860

aaggcaauca uggaguucaa ucccagggaa guggcaagga auguauuuga guguaaugau     1920

caggugguga aaggcaagga agccggagag gucagagucu gccuccaugu ccagaagagc     1980

acacgggauc ggcuaagaga aggacagauc cagaguguug ugacuuauga ccuggcucug     2040

gacuccggcc gcccacauuc ccgcgccguc uucaaugaga caaagaacag cacacgcaga     2100

cagacacagg ucuuggggcu gacccagacu ugugagaccc ugaaacuaca guugccgaau     2160

ugcaucgagg acccagugag ccccauugug cugcgccuga acuucucucu ggugggaacg     2220

ccauugucug cuuucgggaa ccuccggcca gugcuggcgg aggaugcuca gagacucuuc     2280

acagccuugu uucccuuuga gaagaauugu ggcaaugaca acaucugcca ggaugaccuc     2340

agcaucaccu ucaguuucau gagccuggac ugccucgugg ugggugggcc ccgggaguuc     2400

aacgugacag ugacugugag aaaugauggu gaggacuccu acaggacaca ggucaccuuc     2460

uucuucccgc uugaccuguc cuaccggaag guguccacgc uccagaacca gcgcucacag     2520

cgauccuggc gccuggccug ugagucugcc uccuccaccg aagugucugg ggccuugaag     2580

agcaccagcu gcagcauaaa ccaccccauc uucccggaaa acucagaggu caccuuuaau     2640

aucacguuug auguagacuc uaaggcuucc cuuggaaaca aacugcuccu caaggccaau     2700

gugaccagug agaacaacau gcccagaacc aacaaaaccg aauuccaacu ggagcugccg     2760

gugaaauaug cugucuacau gguggucacc agccaugggg ucuccacuaa auaucucaac     2820

uucacggccu cagagaauac cagucggguc augcagcauc aauaucaggu cagcaaccug     2880

gggcagagga gccuccccau cagccuggug uucuuggugc ccguccggcu gaaccagacu     2940

gucauauggg accgccccca ggucaccuuc uccgagaacc ucucgaguac gugccacacc     3000

aaggagcgcu ugcccucuca cuccgacuuu cuggcugagc uucggaaggc ccccguggug     3060

aacugcucca ucgcugucug ccagagaauc cagugugaca ucccguucuu uggcauccag     3120

gaagaauuca augcuacccu caaaggcaac cucucguuug acugguacau caagaccucg     3180

cauaaccacc uccugaucgu gagcacagcu gagaucuugu uuaacgauuc cguguucacc     3240

cugcugccgg gacagggggc guuugugagg ucccagacgg agaccaaagu ggagccguuc     3300

gaggucccca acccccugcc gcucaucgug ggcagcucug ucgggggacu gcugcuccug     3360

gcccucauca ccgccgcgcu guacaagcuc ggcuucuuca agcggcaaua caaggacaug     3420

augagugaag gggguccccc gggggccgaa ccccaguag                            3459


<210>  191
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  191
auguucuccc ugaagacgcu uccauuucug cucuuacucc augugcagau uuccaaggcc       60

uuuccuguau cuucuaaaga gaaaaauaca aaaacuguuc aggacuaccu ggaaaaguuc      120

uaccaauuac caagcaacca guaucagucu acaaggaaga auggcacuaa ugugaucguu      180

gaaaagcuua aagaaaugca gcgauuuuuu ggguugaaug ugacggggaa gccaaaugag      240

gaaacucugg acaugaugaa aaagccucgc uguggagugc cugacagugg ugguuuuaug      300

uuaaccccag gaaaccccaa gugggaacgc acuaacuuga ccuacaggau ucgaaacuau      360

accccacagc ugucagaggc ugagguagaa agagcuauca aggaugccuu ugaacucugg      420

aguguugcau caccucucau cuucaccagg aucucacagg gagaggcaga uaucaacauu      480

gcuuuuuacc aaagagauca cggugacaau ucuccauuug auggacccaa uggaauccuu      540

gcucaugccu uucagccagg ccaagguauu ggaggagaug cucauuuuga ugccgaagaa      600

acauggacca acaccuccgc aaauuacaac uuguuucuug uugcugcuca ugaauuuggc      660

cauucuuugg ggcucgcuca cuccucugac ccuggugccu ugauguaucc caacuaugcu      720

uucagggaaa ccagcaacua cucacucccu caagaugaca ucgauggcau ucaggccauc      780

uauggacuuu caagcaaccc uauccaaccu acuggaccaa gcacacccaa acccugugac      840

cccaguuuga cauuugaugc uaucaccaca cuccguggag aaauacuuuu cuuuaaagac      900

agguacuucu ggagaaggca uccucagcua caaagagucg aaaugaauuu uauuucucua      960

uucuggccau cccuuccaac ugguauacag gcugcuuaug aagauuuuga cagagaccuc     1020

auuuuccuau uuaaaggcaa ccaauacugg gcucugagug gcuaugauau ucugcaaggu     1080

uaucccaagg auauaucaaa cuauggcuuc cccagcagcg uccaagcaau ugacgcagcu     1140

guuuucuaca gaaguaaaac auacuucuuu guaaaugacc aauucuggag auaugauaac     1200

caaagacaau ucauggagcc agguuauccc aaaagcauau caggugccuu uccaggaaua     1260

gagaguaaag uugaugcagu uuuccagcaa gaacauuucu uccaugucuu caguggacca     1320

agauauuacg cauuugaucu uauugcucag agaguuacca gaguugcaag aggcaauaaa     1380

uggcuuaacu guagauaugg cuga                                            1404


<210>  192
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  192
augagccucu ggcagccccu gguccuggug cuccuggugc ugggcugcug cuuugcugcc       60

cccagacagc gccaguccac ccuugugcuc uucccuggag accugagaac caaucucacc      120

gacaggcagc uggcagagga auaccuguac cgcuaugguu acacucgggu ggcagagaug      180

cguggagagu cgaaaucucu ggggccugcg cugcugcuuc uccagaagca acugucccug      240

cccgagaccg gugagcugga uagcgccacg cugaaggcca ugcgaacccc acggugcggg      300

gucccagacc ugggcagauu ccaaaccuuu gagggcgacc ucaaguggca ccaccacaac      360

aucaccuauu ggauccaaaa cuacucggaa gacuugccgc gggcggugau ugacgacgcc      420

uuugcccgcg ccuucgcacu guggagcgcg gugacgccgc ucaccuucac ucgcguguac      480

agccgggacg cagacaucgu cauccaguuu ggugucgcgg agcacggaga cggguauccc      540

uucgacggga aggacgggcu ccuggcacac gccuuuccuc cuggccccgg cauucaggga      600

gacgcccauu ucgacgauga cgaguugugg ucccugggca agggcgucgu gguuccaacu      660

cgguuuggaa acgcagaugg cgcggccugc cacuuccccu ucaucuucga gggccgcucc      720

uacucugccu gcaccaccga cggucgcucc gacggcuugc ccuggugcag uaccacggcc      780

aacuacgaca ccgacgaccg guuuggcuuc ugccccagcg agagacucua cacccaggac      840

ggcaaugcug augggaaacc cugccaguuu ccauucaucu uccaaggcca auccuacucc      900

gccugcacca cggacggucg cuccgacggc uaccgcuggu gcgccaccac cgccaacuac      960

gaccgggaca agcucuucgg cuucugcccg acccgagcug acucgacggu gauggggggc     1020

aacucggcgg gggagcugug cgucuucccc uucacuuucc uggguaagga guacucgacc     1080

uguaccagcg agggccgcgg agaugggcgc cucuggugcg cuaccaccuc gaacuuugac     1140

agcgacaaga aguggggcuu cugcccggac caaggauaca guuuguuccu cguggcggcg     1200

caugaguucg gccacgcgcu gggcuuagau cauuccucag ugccggaggc gcucauguac     1260

ccuauguacc gcuucacuga ggggcccccc uugcauaagg acgacgugaa uggcauccgg     1320

caccucuaug guccucgccc ugaaccugag ccacggccuc caaccaccac cacaccgcag     1380

cccacggcuc ccccgacggu cugccccacc ggacccccca cuguccaccc cucagagcgc     1440

cccacagcug gccccacagg uccccccuca gcuggcccca cagguccccc cacugcuggc     1500

ccuucuacgg ccacuacugu gccuuugagu ccgguggacg augccugcaa cgugaacauc     1560

uucgacgcca ucgcggagau ugggaaccag cuguauuugu ucaaggaugg gaaguacugg     1620

cgauucucug agggcagggg gagccggccg cagggccccu uccuuaucgc cgacaagugg     1680

cccgcgcugc cccgcaagcu ggacucgguc uuugaggagc ggcucuccaa gaagcuuuuc     1740

uucuucucug ggcgccaggu guggguguac acaggcgcgu cggugcuggg cccgaggcgu     1800

cuggacaagc ugggccuggg agccgacgug gcccagguga ccggggcccu ccggaguggc     1860

agggggaaga ugcugcuguu cagcgggcgg cgccucugga gguucgacgu gaaggcgcag     1920

augguggauc cccggagcgc cagcgaggug gaccggaugu uccccggggu gccuuuggac     1980

acgcacgacg ucuuccagua ccgagagaaa gccuauuucu gccaggaccg cuucuacugg     2040

cgcgugaguu cccggaguga guugaaccag guggaccaag ugggcuacgu gaccuaugac     2100

auccugcagu gcccugagga cuag                                            2124


<210>  193
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  193
augcauccag ggguccuggc ugccuuccuc uucuugagcu ggacucauug ucgggcccug       60

ccccuuccca guggugguga ugaagaugau uugucugagg aagaccucca guuugcagag      120

cgcuaccuga gaucauacua ccauccuaca aaucucgcgg gaauccugaa ggagaaugca      180

gcaagcucca ugacugagag gcuccgagaa augcagucuu ucuucggcuu agaggugacu      240

ggcaaacuug acgauaacac cuuagauguc augaaaaagc caagaugcgg gguuccugau      300

gugggugaau acaauguuuu cccucgaacu cuuaaauggu ccaaaaugaa uuuaaccuac      360

agaauuguga auuacacccc ugauaugacu cauucugaag ucgaaaaggc auucaaaaaa      420

gccuucaaag uuugguccga uguaacuccu cugaauuuua ccagacuuca cgauggcauu      480

gcugacauca ugaucucuuu uggaauuaag gagcauggcg acuucuaccc auuugauggg      540

cccucuggcc ugcuggcuca ugcuuuuccu ccugggccaa auuauggagg agaugcccau      600

uuugaugaug augaaaccug gacaaguagu uccaaaggcu acaacuuguu ucuuguugcu      660

gcgcaugagu ucggccacuc cuuaggucuu gaccacucca aggacccugg agcacucaug      720

uuuccuaucu acaccuacac cggcaaaagc cacuuuaugc uuccugauga cgauguacaa      780

gggauccagu cucucuaugg uccaggagau gaagacccca acccuaaaca uccaaaaacg      840

ccagacaaau gugacccuuc cuuaucccuu gaugccauua ccagucuccg aggagaaaca      900

augaucuuua aagacagauu cuucuggcgc cugcauccuc agcagguuga ugcggagcug      960

uuuuuaacga aaucauuuug gccagaacuu cccaaccgua uugaugcugc auaugagcac     1020

ccuucucaug accucaucuu caucuucaga gguagaaaau uuugggcucu uaaugguuau     1080

gacauucugg aagguuaucc caaaaaaaua ucugaacugg gucuuccaaa agaaguuaag     1140

aagauaagug cagcuguuca cuuugaggau acaggcaaga cucuccuguu cucaggaaac     1200

caggucugga gauaugauga uacuaaccau auuauggaua aagacuaucc gagacuaaua     1260

gaagaagacu ucccaggaau uggugauaaa guagaugcug ucuaugagaa aaaugguuau     1320

aucuauuuuu ucaacggacc cauacaguuu gaauacagca ucuggaguaa ccguauuguu     1380

cgcgucaugc cagcaaauuc cauuuugugg uguuaa                               1416


<210>  194
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  194
auggaaacuc caaacaccac agaggacuau gacacgacca cagaguuuga cuauggggau       60

gcaacuccgu gccagaaggu gaacgagagg gccuuugggg cccaacugcu gcccccucug      120

uacuccuugg uauuugucau uggccugguu ggaaacaucc uggugguccu gguccuugug      180

caauacaaga ggcuaaaaaa caugaccagc aucuaccucc ugaaccuggc cauuucugac      240

cugcucuucc uguucacgcu ucccuucugg aucgacuaca aguugaagga ugacuggguu      300

uuuggugaug ccauguguaa gauccucucu ggguuuuauu acacaggcuu guacagcgag      360

aucuuuuuca ucauccugcu gacgauugac agguaccugg ccaucgucca cgccguguuu      420

gccuugcggg cacggaccgu cacuuuuggu gucaucacca gcaucaucau uugggcccug      480

gccaucuugg cuuccaugcc aggcuuauac uuuuccaaga cccaauggga auucacucac      540

cacaccugca gccuucacuu uccucacgaa agccuacgag aguggaagcu guuucaggcu      600

cugaaacuga accucuuugg gcugguauug ccuuuguugg ucaugaucau cugcuacaca      660

gggauuauaa agauucugcu aagacgacca aaugagaaga aauccaaagc uguccguuug      720

auuuuuguca ucaugaucau cuuuuuucuc uuuuggaccc ccuacaauuu gacuauacuu      780

auuucuguuu uccaagacuu ccuguucacc caugagugug agcagagcag acauuuggac      840

cuggcugugc aagugacgga ggugaucgcc uacacgcacu gcugugucaa cccagugauc      900

uacgccuucg uuggugagag guuccggaag uaccugcggc aguuguucca caggcgugug      960

gcugugcacc ugguuaaaug gcuccccuuc cucuccgugg acaggcugga gagggucagc     1020

uccacaucuc ccuccacagg ggagcaugaa cucucugcug gguucuga                  1068


<210>  195
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  195
augaggaccu uggcuugccu gcugcuccuc ggcugcggau accucgccca uguucuggcc       60

gaggaagccg agaucccccg cgaggugauc gagaggcugg cccgcaguca gauccacagc      120

auccgggacc uccagcgacu ccuggagaua gacuccguag ggagugagga uucuuuggac      180

accagccuga gagcucacgg gguccaugcc acuaagcaug ugcccgagaa gcggccccug      240

cccauucgga ggaagagaag caucgaggaa gcuguccccg cugucugcaa gaccaggacg      300

gucauuuacg agauuccucg gagucagguc gaccccacgu ccgccaacuu ccugaucugg      360

cccccgugcg uggaggugaa acgcugcacc ggcugcugca acacgagcag ugucaagugc      420

cagcccuccc gcguccacca ccgcagcguc aagguggcca agguggaaua cgucaggaag      480

aagccaaaau uaaaagaagu ccaggugagg uuagaggagc auuuggagug cgccugcgcg      540

accacaagcc ugaauccgga uuaucgggaa gaggacacgg gaaggccuag ggagucaggu      600

aaaaaacgga aaagaaaaag guuaaaaccc accuaa                                636


<210>  196
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  196
augaaucgcu gcugggcgcu cuuccugucu cucugcugcu accugcgucu ggucagcgcc       60

gagggggacc ccauucccga ggagcuuuau gagaugcuga gugaccacuc gauccgcucc      120

uuugaugauc uccaacgccu gcugcacgga gaccccggag aggaagaugg ggccgaguug      180

gaccugaaca ugacccgcuc ccacucugga ggcgagcugg agagcuuggc ucguggaaga      240

aggagccugg guucccugac cauugcugag ccggccauga ucgccgagug caagacgcgc      300

accgaggugu ucgagaucuc ccggcgccuc auagaccgca ccaacgccaa cuuccuggug      360

uggccgcccu guguggaggu gcagcgcugc uccggcugcu gcaacaaccg caacgugcag      420

ugccgcccca cccaggugca gcugcgaccu guccagguga gaaagaucga gauugugcgg      480

aagaagccaa ucuuuaagaa ggccacggug acgcuggaag accaccuggc augcaagugu      540

gagacagugg cagcugcacg gccugugacc cgaagcccgg gggguuccca ggagcagcga      600

gccaaaacgc cccaaacucg ggugaccauu cggacggugc gaguccgccg gccccccaag      660

ggcaagcacc ggaaauucaa gcacacgcau gacaagacgg cacugaagga gacccuugga      720

gccuag                                                                 726


<210>  197
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  197
augagccucu ucgggcuucu ccugcugaca ucugcccugg ccggccagag acaggggacu       60

caggcggaau ccaaccugag uaguaaauuc caguuuucca gcaacaagga acagaacgga      120

guacaagauc cucagcauga gagaauuauu acugugucua cuaauggaag uauucacagc      180

ccaagguuuc cucauacuua uccaagaaau acggucuugg uauggagauu aguagcagua      240

gaggaaaaug uauggauaca acuuacguuu gaugaaagau uugggcuuga agacccagaa      300

gaugacauau gcaaguauga uuuuguagaa guugaggaac ccagugaugg aacuauauua      360

gggcgcuggu gugguucugg uacuguacca ggaaaacaga uuucuaaagg aaaucaaauu      420

aggauaagau uuguaucuga ugaauauuuu ccuucugaac caggguucug cauccacuac      480

aacauuguca ugccacaauu cacagaagcu gugaguccuu cagugcuacc cccuucagcu      540

uugccacugg accugcuuaa uaaugcuaua acugccuuua guaccuugga agaccuuauu      600

cgauaucuug aaccagagag auggcaguug gacuuagaag aucuauauag gccaacuugg      660

caacuucuug gcaaggcuuu uguuuuugga agaaaaucca gaguggugga ucugaaccuu      720

cuaacagagg agguaagauu auacagcugc acaccucgua acuucucagu guccauaagg      780

gaagaacuaa agagaaccga uaccauuuuc uggccagguu gucuccuggu uaaacgcugu      840

ggugggaacu gugccuguug ucuccacaau ugcaaugaau gucaaugugu cccaagcaaa      900

guuacuaaaa aauaccacga gguccuucag uugagaccaa agaccggugu caggggauug      960

cacaaaucac ucaccgacgu ggcccuggag caccaugagg agugugacug ugugugcaga     1020

gggagcacag gaggauag                                                   1038


<210>  198
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  198
augcaccggc ucaucuuugu cuacacucua aucugcgcaa acuuuugcag cugucgggac       60

acuucugcaa ccccgcagag cgcauccauc aaagcuuugc gcaacgccaa ccucaggcga      120

gaugacuugu accgaagaga ugagaccauc caggugaaag gaaacggcua cgugcagagu      180

ccuagauucc cgaacagcua ccccaggaac cugcuccuga cauggcggcu ucacucucag      240

gagaauacac ggauacagcu aguguuugac aaucaguuug gauuagagga agcagaaaau      300

gauaucugua gguaugauuu uguggaaguu gaagauauau ccgaaaccag uaccauuauu      360

agaggacgau gguguggaca caaggaaguu ccuccaagga uaaaaucaag aacgaaccaa      420

auuaaaauca cauucaaguc cgaugacuac uuuguggcua aaccuggauu caagauuuau      480

uauucuuugc uggaagauuu ccaacccgca gcagcuucag agaccaacug ggaaucuguc      540

acaagcucua uuucaggggu auccuauaac ucuccaucag uaacggaucc cacucugauu      600

gcggaugcuc uggacaaaaa aauugcagaa uuugauacag uggaagaucu gcucaaguac      660

uucaauccag agucauggca agaagaucuu gagaauaugu aucuggacac cccucgguau      720

cgaggcaggu cauaccauga ccggaaguca aaaguugacc uggauaggcu caaugaugau      780

gccaagcguu acaguugcac ucccaggaau uacucgguca auauaagaga agagcugaag      840

uuggccaaug uggucuucuu uccacguugc cuccucgugc agcgcugugg aggaaauugu      900

ggcuguggaa cugucaacug gagguccugc acaugcaauu cagggaaaac cgugaaaaag      960

uaucaugagg uauuacaguu ugagccuggc cacaucaaga ggagggguag agcuaagacc     1020

auggcucuag uugacaucca guuggaucac caugaacgau gugauuguau cugcagcuca     1080

agaccaccuc gauaa                                                      1095


<210>  199
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  199
auggucaccc acagcaaguu ucccgccgcc gggaugagcc gcccccugga caccagccug       60

cgccucaaga ccuucagcuc caagagcgag uaccagcugg uggugaacgc agugcgcaag      120

cugcaggaga gcggcuucua cuggagcgca gugaccggcg gcgaggcgaa ccugcugcuc      180

agugccgagc ccgccggcac cuuucugauc cgcgacagcu cggaccagcg ccacuucuuc      240

acgcucagcg ucaagaccca gucugggacc aagaaccugc gcauccagug ugaggggggc      300

agcuucucuc ugcagagcga uccccggagc acgcagcccg ugccccgcuu cgacugcgug      360

cucaagcugg ugcaccacua caugccgccc ccuggagccc ccuccuuccc cucgccaccu      420

acugaacccu ccuccgaggu gcccgagcag ccgucugccc agccacuccc ugggaguccc      480

cccagaagag ccuauuacau cuacuccggg ggcgagaaga ucccccuggu guugagccgg      540

ccccucuccu ccaacguggc cacucuucag caucucuguc ggaagaccgu caacggccac      600

cuggacuccu augagaaagu cacccagcug ccggggccca uucgggaguu ccuggaccag      660

uacgaugccc cgcuuuaa                                                    678


<210>  200
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  200
augguccccu cggcuggaca gcucgcccug uucgcucugg guauuguguu ggcugcgugc       60

caggccuugg agaacagcac guccccgcug agugcagacc cgcccguggc ugcagcagug      120

gugucccauu uuaaugacug cccagauucc cacacucagu ucugcuucca uggaaccugc      180

agguuuuugg ugcaggagga caagccagca ugugucugcc auucugggua cguuggugca      240

cgcugugagc augcggaccu ccuggccgug guggcugcca gccagaagaa gcaggccauc      300

accgccuugg ugguggucuc caucguggcc cuggcugucc uuaucaucac augugugcug      360

auacacugcu gccagguccg aaaacacugu gaguggugcc gggcccucau cugccggcac      420

gagaagccca gcgcccuccu gaagggaaga accgcuugcu gccacucaga aacagugguc      480

uga                                                                    483


<210>  201
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  201
augccgcccu ccgggcugcg gcugcugccg cugcugcuac cgcugcugug gcuacuggug       60

cugacgccug gccggccggc cgcgggacua uccaccugca agacuaucga cauggagcug      120

gugaagcgga agcgcaucga ggccauccgc ggccagaucc uguccaagcu gcggcucgcc      180

agccccccga gccaggggga ggugccgccc ggcccgcugc ccgaggccgu gcucgcccug      240

uacaacagca cccgcgaccg gguggccggg gagagugcag aaccggagcc cgagccugag      300

gccgacuacu acgccaagga ggucacccgc gugcuaaugg uggaaaccca caacgaaauc      360

uaugacaagu ucaagcagag uacacacagc auauauaugu ucuucaacac aucagagcuc      420

cgagaagcgg uaccugaacc cguguugcuc ucccgggcag agcugcgucu gcugaggcuc      480

aaguuaaaag uggagcagca cguggagcug uaccagaaau acagcaacaa uuccuggcga      540

uaccucagca accggcugcu ggcacccagc gacucgccag agugguuauc uuuugauguc      600

accggaguug ugcggcagug guugagccgu ggaggggaaa uugagggcuu ucgccuuagc      660

gcccacugcu ccugugacag cagggauaac acacugcaag uggacaucaa cggguucacu      720

accggccgcc gaggugaccu ggccaccauu cauggcauga accggccuuu ccugcuucuc      780

auggccaccc cgcuggagag ggcccagcau cugcaaagcu cccggcaccg ccgagcccug      840

gacaccaacu auugcuucag cuccacggag aagaacugcu gcgugcggca gcuguacauu      900

gacuuccgca aggaccucgg cuggaagugg auccacgagc ccaagggcua ccaugccaac      960

uucugccucg ggcccugccc cuacauuugg agccuggaca cgcaguacag caagguccug     1020

gcccuguaca accagcauaa cccgggcgcc ucggcggcgc cgugcugcgu gccgcaggcg     1080

cuggagccgc ugcccaucgu guacuacgug ggccgcaagc ccaaggugga gcagcugucc     1140

aacaugaucg ugcgcuccug caagugcagc uga                                  1173


<210>  202
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  202
augcacuacu gugugcugag cgcuuuucug auccugcauc uggucacggu cgcgcucagc       60

cugucuaccu gcagcacacu cgauauggac caguucaugc gcaagaggau cgaggcgauc      120

cgcgggcaga uccugagcaa gcugaagcuc accagucccc cagaagacua uccugagccc      180

gaggaagucc ccccggaggu gauuuccauc uacaacagca ccagggacuu gcuccaggag      240

aaggcgagcc ggagggcggc cgccugcgag cgcgagagga gcgacgaaga guacuacgcc      300

aaggagguuu acaaaauaga caugccgccc uucuuccccu ccgaaaaugc caucccgccc      360

acuuucuaca gacccuacuu cagaauuguu cgauuugacg ucucagcaau ggagaagaau      420

gcuuccaauu uggugaaagc agaguucaga gucuuucguu ugcagaaccc aaaagccaga      480

gugccugaac aacggauuga gcuauaucag auucucaagu ccaaagauuu aacaucucca      540

acccagcgcu acaucgacag caaaguugug aaaacaagag cagaaggcga auggcucucc      600

uucgauguaa cugaugcugu ucaugaaugg cuucaccaua aagacaggaa ccugggauuu      660

aaaauaagcu uacacugucc cugcugcacu uuuguaccau cuaauaauua caucauccca      720

aauaaaagug aagaacuaga agcaagauuu gcagguauug auggcaccuc cacauauacc      780

aguggugauc agaaaacuau aaaguccacu aggaaaaaaa acagugggaa gaccccacau      840

cuccugcuaa uguuauugcc cuccuacaga cuugagucac aacagaccaa ccggcggaag      900

aagcgugcuu uggaugcggc cuauugcuuu agaaaugugc aggauaauug cugccuacgu      960

ccacuuuaca uugauuucaa gagggaucua ggguggaaau ggauacacga acccaaaggg     1020

uacaaugcca acuucugugc uggagcaugc ccguauuuau ggaguucaga cacucagcac     1080

agcagggucc ugagcuuaua uaauaccaua aauccagaag caucugcuuc uccuugcugc     1140

gugucccaag auuuagaacc ucuaaccauu cucuacuaca uuggcaaaac acccaagauu     1200

gaacagcuuu cuaauaugau uguaaagucu ugcaaaugca gcuaa                     1245


<210>  203
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  203
augaagaugc acuugcaaag ggcucuggug guccuggccc ugcugaacuu ugccacgguc       60

agccucucuc uguccacuug caccaccuug gacuucggcc acaucaagaa gaagagggug      120

gaagccauua ggggacagau cuugagcaag cucaggcuca ccagcccccc ugagccaacg      180

gugaugaccc acguccccua ucagguccug gcccuuuaca acagcacccg ggagcugcug      240

gaggagaugc auggggagag ggaggaaggc ugcacccagg aaaacaccga gucggaauac      300

uaugccaaag aaauccauaa auucgacaug auccaggggc uggcggagca caacgaacug      360

gcugucugcc cuaaaggaau uaccuccaag guuuuccgcu ucaauguguc cucaguggag      420

aaaaauagaa ccaaccuauu ccgagcagaa uuccgggucu ugcgggugcc caaccccagc      480

ucuaagcgga augagcagag gaucgagcuc uuccagaucc uucggccaga ugagcacauu      540

gccaaacagc gcuauaucgg uggcaagaau cugcccacac ggggcacugc cgaguggcug      600

uccuuugaug ucacugacac ugugcgugag uggcuguuga gaagagaguc caacuuaggu      660

cuagaaauca gcauucacug uccaugucac accuuucagc ccaauggaga uauccuggaa      720

aacauucacg aggugaugga aaucaaauuc aaaggcgugg acaaugagga ugaccauggc      780

cguggagauc uggggcgccu caagaagcag aaggaucacc acaacccuca ucuaauccuc      840

augaugauuc ccccacaccg gcucgacaac ccgggccagg ggggucagag gaagaagcgg      900

gcuuuggaca ccaauuacug cuuccgcaac uuggaggaga acugcugugu gcgcccccuc      960

uacauugacu uccgacagga ucugggcugg aagugggucc augaaccuaa gggcuacuau     1020

gccaacuucu gcucaggccc uugcccauac cuccgcagug cagacacaac ccacagcacg     1080

gugcugggac uguacaacac ucugaacccu gaagcaucug ccucgccuug cugcgugccc     1140

caggaccugg agccccugac cauccuguac uauguuggga ggacccccaa aguggagcag     1200

cucuccaaca ugguggugaa gucuuguaaa uguagcuga                            1239


<210>  204
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  204
auggcgcccg ucgccgucug ggccgcgcug gccgucggac uggagcucug ggcugcggcg       60

cacgccuugc ccgcccaggu ggcauuuaca cccuacgccc cggagcccgg gagcacaugc      120

cggcucagag aauacuauga ccagacagcu cagaugugcu gcagcaaaug cucgccgggc      180

caacaugcaa aagucuucug uaccaagacc ucggacaccg ugugugacuc cugugaggac      240

agcacauaca cccagcucug gaacuggguu cccgagugcu ugagcugugg cucccgcugu      300

agcucugacc agguggaaac ucaagccugc acucgggaac agaaccgcau cugcaccugc      360

aggcccggcu gguacugcgc gcugagcaag caggaggggu gccggcugug cgcgccgcug      420

cgcaagugcc gcccgggcuu cggcguggcc agaccaggaa cugaaacauc agacguggug      480

ugcaagcccu gugccccggg gacguucucc aacacgacuu cauccacgga uauuugcagg      540

ccccaccaga ucuguaacgu gguggccauc ccugggaaug caagcaugga ugcagucugc      600

acguccacgu cccccacccg gaguauggcc ccaggggcag uacacuuacc ccagccagug      660

uccacacgau cccaacacac gcagccaacu ccagaaccca gcacugcucc aagcaccucc      720

uuccugcucc caaugggccc cagcccccca gcugaaggga gcacuggcga cuucgcucuu      780

ccaguuggac ugauuguggg ugugacagcc uugggucuac uaauaauagg aguggugaac      840

ugugucauca ugacccaggu gaaaaagaag cccuugugcc ugcagagaga agccaaggug      900

ccucacuugc cugccgauaa ggcccggggu acacagggcc ccgagcagca gcaccugcug      960

aucacagcgc cgagcuccag cagcagcucc cuggagagcu cggccagugc guuggacaga     1020

agggcgccca cucggaacca gccacaggca ccaggcgugg aggccagugg ggccggggag     1080

gcccgggcca gcaccgggag cucagauucu uccccuggug gccaugggac ccaggucaau     1140

gucaccugca ucgugaacgu cuguagcagc ucugaccaca gcucacagug cuccucccaa     1200

gccagcucca caaugggaga cacagauucc agccccucgg aguccccgaa ggacgagcag     1260

guccccuucu ccaaggagga augugccuuu cggucacagc uggagacgcc agagacccug     1320

cuggggagca ccgaagagaa gccccugccc cuuggagugc cugaugcugg gaugaagccc     1380

aguuaa                                                                1386


<210>  205
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  205
augccgguca ugaggcuguu cccuugcuuc cugcagcucc uggccgggcu ggcgcugccu       60

gcugugcccc cccagcagug ggccuugucu gcugggaacg gcucgucaga gguggaagug      120

guacccuucc aggaagugug gggccgcagc uacugccggg cgcuggagag gcugguggac      180

gucguguccg aguaccccag cgagguggag cacauguuca gcccauccug ugucucccug      240

cugcgcugca ccggcugcug cggcgaugag aaucugcacu gugugccggu ggagacggcc      300

aaugucacca ugcagcuccu aaagauccgu ucuggggacc ggcccuccua cguggagcug      360

acguucucuc agcacguucg cugcgaaugc cggccucugc gggagaagau gaagccggaa      420

aggaggagac ccaagggcag ggggaagagg aggagagaga agcagagacc cacagacugc      480

caccugugcg gcgaugcugu uccccggagg uaa                                   513


<210>  206
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  206
augacggaca gacagacaga caccgccccc agccccagcu accaccuccu ccccggccgg       60

cggcggacag uggacgcggc ggcgagccgc gggcaggggc cggagcccgc gcccggaggc      120

gggguggagg gggucggggc ucgcggcguc gcacugaaac uuuucgucca acuucugggc      180

uguucucgcu ucggaggagc cgugguccgc gcgggggaag ccgagccgag cggagccgcg      240

agaagugcua gcucgggccg ggaggagccg cagccggagg agggggagga ggaagaagag      300

aaggaagagg agagggggcc gcaguggcga cucggcgcuc ggaagccggg cucauggacg      360

ggugaggcgg cggugugcgc agacagugcu ccagccgcgc gcgcucccca ggcccuggcc      420

cgggccucgg gccggggagg aagaguagcu cgccgaggcg ccgaggagag cgggccgccc      480

cacagcccga gccggagagg gagcgcgagc cgcgccggcc ccggucgggc cuccgaaacc      540

augaacuuuc ugcugucuug ggugcauugg agccuugccu ugcugcucua ccuccaccau      600

gccaaguggu cccaggcugc acccauggca gaaggaggag ggcagaauca ucacgaagug      660

gugaaguuca uggaugucua ucagcgcagc uacugccauc caaucgagac ccugguggac      720

aucuuccagg aguacccuga ugagaucgag uacaucuuca agccauccug ugugccccug      780

augcgaugcg ggggcugcug caaugacgag ggccuggagu gugugcccac ugaggagucc      840

aacaucacca ugcagauuau gcggaucaaa ccucaccaag gccagcacau aggagagaug      900

agcuuccuac agcacaacaa augugaaugc agaccaaaga aagauagagc aagacaagaa      960

aaaaaaucag uucgaggaaa gggaaagggg caaaaacgaa agcgcaagaa aucccgguau     1020

aaguccugga gcguguacgu uggugcccgc ugcugucuaa ugcccuggag ccucccuggc     1080

ccccaucccu gugggccuug cucagagcgg agaaagcauu uguuuguaca agauccgcag     1140

acguguaaau guuccugcaa aaacacagac ucgcguugca aggcgaggca gcuugaguua     1200

aacgaacgua cuugcagaug ugacaagccg aggcgguga                            1239


<210>  207
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  207
augaacuuuc ugcugucuug ggugcauugg agccuugccu ugcugcucua ccuccaccau       60

gccaaguggu cccaggcugc acccauggca gaaggaggag ggcagaauca ucacgaagug      120

gugaaguuca uggaugucua ucagcgcagc uacugccauc caaucgagac ccugguggac      180

aucuuccagg aguacccuga ugagaucgag uacaucuuca agccauccug ugugccccug      240

augcgaugcg ggggcugcug caaugacgag ggccuggagu gugugcccac ugaggagucc      300

aacaucacca ugcagauuau gcggaucaaa ccucaccaag gccagcacau aggagagaug      360

agcuuccuac agcacaacaa augugaaugc agaccaaaga aagauagagc aagacaagaa      420

aaaaaaucag uucgaggaaa gggaaagggg caaaaacgaa agcgcaagaa aucccgguau      480

aaguccugga gcguguacgu uggugcccgc ugcugucuaa ugcccuggag ccucccuggc      540

ccccaucccu gugggccuug cucagagcgg agaaagcauu uguuuguaca agauccgcag      600

acguguaaau guuccugcaa aaacacagac ucgcguugca aggcgaggca gcuugaguua      660

aacgaacgua cuugcagaug ugacaagccg aggcgguga                             699


<210>  208
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  208
augagcccuc ugcuccgccg ccugcugcuc gccgcacucc ugcagcuggc ccccgcccag       60

gccccugucu cccagccuga ugccccuggc caccagagga aagugguguc auggauagau      120

guguauacuc gcgcuaccug ccagccccgg gagguggugg ugcccuugac uguggagcuc      180

augggcaccg uggccaaaca gcuggugccc agcugcguga cugugcagcg cugugguggc      240

ugcugcccug acgauggccu ggagugugug cccacugggc agcaccaagu ccggaugcag      300

auccucauga uccgguaccc gagcagucag cugggggaga ugucccugga agaacacagc      360

cagugugaau gcagaccuaa aaaaaaggac agugcuguga agccagacag ggcugccacu      420

ccccaccacc guccccagcc ccguucuguu ccgggcuggg acucugcccc cggagcaccc      480

uccccagcug acaucaccca ucccacucca gccccaggcc ccucugccca cgcugcaccc      540

agcaccacca gcgcccugac ccccggaccu gccgcugccg cugccgacgc cgcagcuucc      600

uccguugcca agggcggggc uuag                                             624


<210>  209
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  209
augcacuugc ugggcuucuu cucuguggcg uguucucugc ucgccgcugc gcugcucccg       60

gguccucgcg aggcgcccgc cgccgccgcc gccuucgagu ccggacucga ccucucggac      120

gcggagcccg acgcgggcga ggccacggcu uaugcaagca aagaucugga ggagcaguua      180

cggucugugu ccaguguaga ugaacucaug acuguacucu acccagaaua uuggaaaaug      240

uacaaguguc agcuaaggaa aggaggcugg caacauaaca gagaacaggc caaccucaac      300

ucaaggacag aagagacuau aaaauuugcu gcagcacauu auaauacaga gaucuugaaa      360

aguauugaua augaguggag aaagacucaa ugcaugccac gggaggugug uauagaugug      420

gggaaggagu uuggagucgc gacaaacacc uucuuuaaac cuccaugugu guccgucuac      480

agaugugggg guugcugcaa uagugagggg cugcagugca ugaacaccag cacgagcuac      540

cucagcaaga cguuauuuga aauuacagug ccucucucuc aaggccccaa accaguaaca      600

aucaguuuug ccaaucacac uuccugccga ugcaugucua aacuggaugu uuacagacaa      660

guucauucca uuauuagacg uucccugcca gcaacacuac cacaguguca ggcagcgaac      720

aagaccugcc ccaccaauua cauguggaau aaucacaucu gcagaugccu ggcucaggaa      780

gauuuuaugu uuuccucgga ugcuggagau gacucaacag auggauucca ugacaucugu      840

ggaccaaaca aggagcugga ugaagagacc ugucagugug ucugcagagc ggggcuucgg      900

ccugccagcu guggacccca caaagaacua gacagaaacu caugccagug ugucuguaaa      960

aacaaacucu uccccagcca auguggggcc aaccgagaau uugaugaaaa cacaugccag     1020

uguguaugua aaagaaccug ccccagaaau caaccccuaa auccuggaaa augugccugu     1080

gaauguacag aaaguccaca gaaaugcuug uuaaaaggaa agaaguucca ccaccaaaca     1140

ugcagcuguu acagacggcc auguacgaac cgccagaagg cuugugagcc aggauuuuca     1200

uauagugaag aagugugucg uugugucccu ucauauugga aaagaccaca aaugagcuaa     1260


<210>  210
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  210
auguacagag aguggguagu ggugaauguu uucaugaugu uguacgucca gcuggugcag       60

ggcuccagua augaacaugg accagugaag cgaucaucuc aguccacauu ggaacgaucu      120

gaacagcaga ucagggcugc uucuaguuug gaggaacuac uucgaauuac ucacucugag      180

gacuggaagc uguggagaug caggcugagg cucaaaaguu uuaccaguau ggacucucgc      240

ucagcauccc aucgguccac uagguuugcg gcaacuuucu augacauuga aacacuaaaa      300

guuauagaug aagaauggca aagaacucag ugcagcccua gagaaacgug cguggaggug      360

gccagugagc uggggaagag uaccaacaca uucuucaagc ccccuugugu gaacguguuc      420

cgauguggug gcuguugcaa ugaagagagc cuuaucugua ugaacaccag caccucguac      480

auuuccaaac agcucuuuga gauaucagug ccuuugacau caguaccuga auuagugccu      540

guuaaaguug ccaaucauac agguuguaag ugcuugccaa cagccccccg ccauccauac      600

ucaauuauca gaagauccau ccagaucccu gaagaagauc gcuguuccca uuccaagaaa      660

cucuguccua uugacaugcu augggauagc aacaaaugua aauguguuuu gcaggaggaa      720

aauccacuug cuggaacaga agaccacucu caucuccagg aaccagcucu cugugggcca      780

cacaugaugu uugacgaaga ucguugcgag ugugucugua aaacaccaug ucccaaagau      840

cuaauccagc accccaaaaa cugcaguugc uuugagugca aagaaagucu ggagaccugc      900

ugccagaagc acaagcuauu ucacccagac accugcagcu gugaggacag augccccuuu      960

cauaccagac caugugcaag uggcaaaaca gcaugugcaa agcauugccg cuuuccaaag     1020

gagaaaaggg cugcccaggg gccccacagc cgaaagaauc cuuga                     1065


<210>  211
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  211
auggccguga uggccccgcg gacccugguc cuccugcuga gcggcgcgcu cgcccugacc       60

cagacguggg cc                                                           72


<210>  212
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  212
auggacgcca ugaagcgcgg ccugugcugc gugcuccugc ugugcggggc cgucuucgug       60

agccccucc                                                               69


<210>  213
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  213
augggcgugc acgagugccc cgccuggcug uggcuccugc ugagccuccu gucccugccg       60

cucgggcugc ccguccuggg c                                                 81


<210>  214
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  214
augaaguggg ugaccuucau cagccugcuc uuccuguucu ccagcgccua cucc             54


<210>  215
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from 
       Artificial____cleavage site-Furin

<400>  215
cgccggcgcc ggaagcgc                                                     18


<210>  216
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  216
auggacagcg acgagaccgg cuucgagcac uccgggcugu gggugagcgu ccucgccggc       60

cugcugcucg gggccugcca ggcccacccc aucccggacu ccagcccccu gcugcaguuc      120

ggcggccagg ugcgccagcg guaccucuac accgacgacg cccagcagac ggaggcccac      180

cuggagaucc gcgaggacgg gaccgugggc ggggccgccg accagucccc cgagagccug      240

cuccagcuga aggcgcugaa gcccggcguc auccagaucc ucggggugaa gaccucccgg      300

uuccugugcc agcgcccgga cggcgcccug uacgggagcc uccacuucga ccccgaggcc      360

ugcuccuucc gggagcugcu gcucgaggac ggcuacaacg uguaccagag cgaggcccac      420

ggccugcccc ugcaccuccc cgggaacaag uccccgcacc gcgaccccgc gccccggggc      480

cccgcccgcu uccugccgcu gcccgggcuc ccgcccgccc ugcccgagcc gcccggcauc      540

cuggcgcccc agccgcccga cgucggcagc uccgaccccc ucagcauggu ggggcccucc      600

cagggccgga gccccuccua cgccagcuga                                       630


<210>  217
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  217
augcacagcu ucccgccccu gcuccugcug cucuucuggg gcguggucuc ccacagcuuc       60

cccgccaccc uggagaccca ggagcaggac guggaccugg ugcagaagua ccucgagaag      120

uacuacaacc ugaagaacga cgggcgccag gucgagaagc ggcgcaacuc cggccccgug      180

guggagaagc ugaagcagau gcaggaguuc uucgggcuca aggucacggg caagcccgac      240

gccgagaccc ugaaggugau gaagcagccg cggugcgggg ugcccgacgu cgcgcaguuc      300

gugcugaccg agggcaaccc ccgcugggag cagacccacc ucacguaccg gaucgagaac      360

uacacccccg accugccgcg cgccgacgug gaccacgcca ucgagaaggc cuuccagcug      420

uggagcaacg ucaccccgcu caccuucacg aagguguccg agggccaggc cgacaucaug      480

aucagcuucg ugcggggcga ccaccgcgac aacucccccu ucgacgggcc cgggggcaac      540

cuggcgcacg ccuuccagcc ggggcccggc aucggcgggg acgcccacuu cgacgaggac      600

gagcggugga ccaacaacuu ccgcgaguac aaccugcacc gggucgccgc gcacgagcuc      660

ggccacagcc uggggcuguc ccacagcacc gacaucggcg cccucaugua ccccuccuac      720

accuucagcg gcgacgugca gcuggcccag gacgacaucg acgggaucca ggccaucuac      780

ggccgcuccc agaaccccgu gcagccgauc gggccccaga cgcccaaggc cugcgacagc      840

aagcugaccu ucgacgcgau caccaccauc cggggcgagg ucauguucuu caaggaccgc      900

uucuacaugc ggacgaaccc cuucuacccg gagguggagc ucaacuucau cuccguguuc      960

uggccccagc ugcccaacgg gcuggaggcc gccuacgagu ucgccgaccg cgacgagguc     1020

cgguucuuca agggcaacaa guacugggcc gugcagggcc agaacgugcu ccacggguac     1080

cccaaggaca ucuacagcuc cuucggcuuc ccgcgcaccg ucaagcacau cgacgcggcc     1140

cugagcgagg agaacaccgg gaagaccuac uucuucgugg ccaacaagua cuggcgguac     1200

gacgaguaca agcgcuccau ggaccccggc uaccccaaga ugaucgccca cgacuucccc     1260

gggaucggcc acaaggucga cgccguguuc augaaggacg gcuucuucua cuucuuccac     1320

gggacgcggc aguacaaguu cgacccgaag accaagcgca uccugacccu ccagaaggcg     1380

aacagcuggu ucaacugccg caagaacuga                                      1410


<210>  218
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  218
augcacagcu ucccgccccu gcuccugcug cucuucuggg gcguggucuc ccacagcuuc       60

gugcugaccg agggcaaccc ccgcugggag cagacccacc ucacguaccg gaucgagaac      120

uacacccccg accugccgcg cgccgacgug gaccacgcca ucgagaaggc cuuccagcug      180

uggagcaacg ucaccccgcu caccuucacg aagguguccg agggccaggc cgacaucaug      240

aucagcuucg ugcggggcga ccaccgcgac aacucccccu ucgacgggcc cgggggcaac      300

cuggcgcacg ccuuccagcc ggggcccggc aucggcgggg acgcccacuu cgacgaggac      360

gagcggugga ccaacaacuu ccgcgaguac aaccugcacc gggucgccgc gcacgagcuc      420

ggccacagcc uggggcuguc ccacagcacc gacaucggcg cccucaugua ccccuccuac      480

accuucagcg gcgacgugca gcuggcccag gacgacaucg acgggaucca ggccaucuac      540

ggccgcuccc agaaccccgu gcagccgauc gggccccaga cgcccaaggc cugcgacagc      600

aagcugaccu ucgacgcgau caccaccauc cggggcgagg ucauguucuu caaggaccgc      660

uucuacaugc ggacgaaccc cuucuacccg gagguggagc ucaacuucau cuccguguuc      720

uggccccagc ugcccaacgg gcuggaggcc gccuacgagu ucgccgaccg cgacgagguc      780

cgguucuuca agggcaacaa guacugggcc gugcagggcc agaacgugcu ccacggguac      840

cccaaggaca ucuacagcuc cuucggcuuc ccgcgcaccg ucaagcacau cgacgcggcc      900

cugagcgagg agaacaccgg gaagaccuac uucuucgugg ccaacaagua cuggcgguac      960

gacgaguaca agcgcuccau ggaccccggc uaccccaaga ugaucgccca cgacuucccc     1020

gggaucggcc acaaggucga cgccguguuc augaaggacg gcuucuucua cuucuuccac     1080

gggacgcggc aguacaaguu cgacccgaag accaagcgca uccugacccu ccagaaggcg     1140

aacagcuggu ucaacugccg caagaacuga                                      1170


<210>  219
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  219
augaagaaga acauccugaa gauccucaug gacagcuacu ccaaggagag caagauccag       60

accgugcgcc gggucaccuc cgugagccug cuggccgugu accucacgau gaacaccucc      120

agccuggucc uggccaagcc caucgagaac accaacgaca ccuccaucaa gaacguggag      180

aagcuccgca acgcgcccaa cgaggagaac agcaagaagg uggaggacuc caagaacgac      240

aaggucgagc acgugaagaa caucgaggag gccaaggugg agcaggucgc ccccgaggug      300

aagagcaagu ccacgcugcg gagcgccucc aucgccaaca ccaacagcga gaaguacgac      360

uucgaguacc ugaacggccu cuccuacacc gagcugacca accugaucaa gaacaucaag      420

uggaaccaga ucaacgggcu cuucaacuac agcacgggcu cccagaaguu cuucggggac      480

aagaaccgcg ugcaggcgau caucaacgcc cugcaggaga gcggccggac cuacaccgcc      540

aacgacauga aggggaucga gaccuucacg gagguccugc gcgccggcuu cuaccucggc      600

uacuacaacg acgggcuguc cuaccugaac gaccggaacu uccaggacaa gugcaucccc      660

gcgaugaucg ccauccagaa gaaccccaac uucaagcucg gcaccgccgu gcaggacgag      720

gugaucacca gccuggggaa gcugaucggc aacgccagcg ccaacgcgga ggucgugaac      780

aacugcgugc cgguccucaa gcaguuccgc gagaaccuga accaguacgc ccccgacuac      840

gugaagggga ccgccgugaa cgagcugauc aagggcaucg aguucgacuu cuccggcgcc      900

gccuacgaga aggacgucaa gacgaugccc ugguacggga agaucgaccc cuucaucaac      960

gagcucaagg cgcugggccu guacgggaac aucaccagcg ccaccgagug ggccuccgac     1020

gugggcaucu acuaccucag caaguucggc cuguacucca ccaaccggaa cgacaucgug     1080

cagagccugg agaaggccgu cgacauguac aaguacggga agaucgccuu cguggcgaug     1140

gagcgcauca cgugggacua cgacggcauc ggguccaacg gcaagaaggu cgaccacgac     1200

aaguuccucg acgacgccga gaagcacuac cugccgaaga ccuacaccuu cgacaacggg     1260

accuucauca uccgggccgg cgacaaggug agcgaggaga agaucaagcg ccuguacugg     1320

gccucccggg aggugaagag ccaguuccac cgcgucgugg gcaacgacaa ggcccucgag     1380

guggggaacg cggacgacgu ccugacgaug aagaucuuca acucccccga ggaguacaag     1440

uucaacacca acaucaacgg cgugagcacc gacaacgggg gccuguacau cgagccgcgg     1500

gggaccuucu acacguacga gcgcaccccg cagcagucca ucuucagccu cgaggagcug     1560

uuccggcacg aguacaccca cuaccugcag gcccgcuacc ucguggacgg ccuguggggc     1620

caggggccgu ucuacgagaa gaaccggcug accugguucg acgagggcac ggccgaguuc     1680

uucgccgggu ccacccgcac cagcggcguc cucccccgga aguccauccu gggguaccug     1740

gcgaaggaca agguggacca ccgcuacagc cucaagaaga cccugaacuc cggcuacgac     1800

gacagcgacu ggauguucua caacuacggc uucgccgugg cccacuaccu guacgagaag     1860

gacaugccca cguucaucaa gaugaacaag gccauccuga acaccgacgu caagagcuac     1920

gacgagauca ucaagaagcu cuccgacgac gccaacaaga acaccgagua ccagaaccac     1980

auccaggagc uggcggacaa guaccagggg gccggcaucc cccuggugag cgacgacuac     2040

cucaaggacc acggguacaa gaaggccucc gagguguaca gcgagaucuc caaggccgcc     2100

agccugacca acaccuccgu cacggcggag aagagccagu acuucaacac cuucacccug     2160

cgcggcaccu acacgggcga gaccuccaag ggggaguuca aggacuggga cgagaugagc     2220

aagaagcucg acggcacccu ggagucccug gccaagaaca gcugguccgg guacaagacc     2280

cucacggccu acuucaccaa cuaccgggug accagcgaca acaaggugca guacgacguc     2340

guguuccacg gcgugcugac cgacaacgcc gacaucucca acaacaaggc cccgaucgcg     2400

aaggucacgg ggcccagcac cggcgccgug ggccgcaaca ucgaguucuc cgggaaggac     2460

agcaaggacg aggacggcaa gaucgugagc uacgacuggg acuucgggga cggcgccacc     2520

ucccggggga agaacagcgu ccacgccuac aagaaggcgg gcaccuacaa cgugacgcug     2580

aaggugaccg acgacaaggg cgccaccgcc accgaguccu ucacgaucga gaucaagaac     2640

gaggacacca ccacccccau cacgaaggag auggagccca acgacgacau caaggaggcc     2700

aacgggccga ucgucgaggg cgugaccgug aagggggacc ucaacggcag cgacgacgcc     2760

gacaccuucu acuucgacgu caaggaggac ggggacguga ccaucgagcu gcccuacucc     2820

ggcagcucca acuucacgug gcugguguac aaggagggcg acgaccagaa ccacaucgcg     2880

agcgggaucg acaagaacaa cuccaagguc ggcaccuuca agagcaccaa ggggcgccac     2940

uacguguuca ucuacaagca cgacuccgcc agcaacaucu ccuacagccu caacaucaag     3000

ggccugggga acgagaagcu gaaggagaag gagaacaacg acuccagcga caaggccacc     3060

gugaucccca acuucaacac gaccaugcag ggcucccucc ugggcgacga cagccgggac     3120

uacuacuccu ucgaggucaa ggaggagggg gaggugaaca ucgagcugga caagaaggac     3180

gaguucggcg ugaccuggac ccuccacccc gagagcaaca ucaacgaccg caucacguac     3240

gggcaggucg acggcaacaa ggugagcaac aaggugaagc ugcggccggg caaguacuac     3300

cugcucgucu acaaguacuc cgggagcggc aacuacgagc ugcgcgugaa caaguga        3357


<210>  220
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  220
augaaguggg ugaccuucau cagccugcuc uuccuguucu ccagcgccua cuccaucgcc       60

aacaccaaca gcgagaagua cgacuucgag uaccugaacg gccucuccua caccgagcug      120

accaaccuga ucaagaacau caaguggaac cagaucaacg ggcucuucaa cuacagcacg      180

ggcucccaga aguucuucgg ggacaagaac cgcgugcagg cgaucaucaa cgcccugcag      240

gagagcggcc ggaccuacac cgccaacgac augaagggga ucgagaccuu cacggagguc      300

cugcgcgccg gcuucuaccu cggcuacuac aacgacgggc uguccuaccu gaacgaccgg      360

aacuuccagg acaagugcau ccccgcgaug aucgccaucc agaagaaccc caacuucaag      420

cucggcaccg ccgugcagga cgaggugauc accagccugg ggaagcugau cggcaacgcc      480

agcgccaacg cggaggucgu gaacaacugc gugccggucc ucaagcaguu ccgcgagaac      540

cugaaccagu acgcccccga cuacgugaag gggaccgccg ugaacgagcu gaucaagggc      600

aucgaguucg acuucuccgg cgccgccuac gagaaggacg ucaagacgau gcccugguac      660

gggaagaucg accccuucau caacgagcuc aaggcgcugg gccuguacgg gaacaucacc      720

agcgccaccg agugggccuc cgacgugggc aucuacuacc ucagcaaguu cggccuguac      780

uccaccaacc ggaacgacau cgugcagagc cuggagaagg ccgucgacau guacaaguac      840

gggaagaucg ccuucguggc gauggagcgc aucacguggg acuacgacgg caucgggucc      900

aacggcaaga aggucgacca cgacaaguuc cucgacgacg ccgagaagca cuaccugccg      960

aagaccuaca ccuucgacaa cgggaccuuc aucauccggg ccggcgacaa ggugagcgag     1020

gagaagauca agcgccugua cugggccucc cgggagguga agagccaguu ccaccgcguc     1080

gugggcaacg acaaggcccu cgaggugggg aacgcggacg acguccugac gaugaagauc     1140

uucaacuccc ccgaggagua caaguucaac accaacauca acggcgugag caccgacaac     1200

gggggccugu acaucgagcc gcgggggacc uucuacacgu acgagcgcac cccgcagcag     1260

uccaucuuca gccucgagga gcuguuccgg cacgaguaca cccacuaccu gcaggcccgc     1320

uaccucgugg acggccugug gggccagggg ccguucuacg agaagaaccg gcugaccugg     1380

uucgacgagg gcacggccga guucuucgcc ggguccaccc gcaccagcgg cguccucccc     1440

cggaagucca uccuggggua ccuggcgaag gacaaggugg accaccgcua cagccucaag     1500

aagacccuga acuccggcua cgacgacagc gacuggaugu ucuacaacua cggcuucgcc     1560

guggcccacu accuguacga gaaggacaug cccacguuca ucaagaugaa caaggccauc     1620

cugaacaccg acgucaagag cuacgacgag aucaucaaga agcucuccga cgacgccaac     1680

aagaacaccg aguaccagaa ccacauccag gagcuggcgg acaaguacca gggggccggc     1740

aucccccugg ugagcgacga cuaccucaag gaccacgggu acaagaaggc cuccgaggug     1800

uacagcgaga ucuccaaggc cgccagccug accaacaccu ccgucacggc ggagaagagc     1860

caguacuuca acaccuucac ccugcgcggc accuacacgg gcgagaccuc caagggggag     1920

uucaaggacu gggacgagau gagcaagaag cucgacggca cccuggaguc ccuggccaag     1980

aacagcuggu ccggguacaa gacccucacg gccuacuuca ccaacuaccg ggugaccagc     2040

gacaacaagg ugcaguacga cgucguguuc cacggcgugc ugaccgacaa cgccgacauc     2100

uccaacaaca aggccccgau cgcgaagguc acggggccca gcaccggcgc cgugggccgc     2160

aacaucgagu ucuccgggaa ggacagcaag gacgaggacg gcaagaucgu gagcuacgac     2220

ugggacuucg gggacggcgc caccucccgg gggaagaaca gcguccacgc cuacaagaag     2280

gcgggcaccu acaacgugac gcugaaggug accgacgaca agggcgccac cgccaccgag     2340

uccuucacga ucgagaucaa gaacgaggac accaccaccc ccaucacgaa ggagauggag     2400

cccaacgacg acaucaagga ggccaacggg ccgaucgucg agggcgugac cgugaagggg     2460

gaccucaacg gcagcgacga cgccgacacc uucuacuucg acgucaagga ggacggggac     2520

gugaccaucg agcugcccua cuccggcagc uccaacuuca cguggcuggu guacaaggag     2580

ggcgacgacc agaaccacau cgcgagcggg aucgacaaga acaacuccaa ggucggcacc     2640

uucaagagca ccaaggggcg ccacuacgug uucaucuaca agcacgacuc cgccagcaac     2700

aucuccuaca gccucaacau caagggccug gggaacgaga agcugaagga gaaggagaac     2760

aacgacucca gcgacaaggc caccgugauc cccaacuuca acacgaccau gcagggcucc     2820

cuccugggcg acgacagccg ggacuacuac uccuucgagg ucaaggagga gggggaggug     2880

aacaucgagc uggacaagaa ggacgaguuc ggcgugaccu ggacccucca ccccgagagc     2940

aacaucaacg accgcaucac guacgggcag gucgacggca acaaggugag caacaaggug     3000

aagcugcggc cgggcaagua cuaccugcuc gucuacaagu acuccgggag cggcaacuac     3060

gagcugcgcg ugaacaagug a                                               3081


<210>  221
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  221
augaaguggg ugaccuucau cagccugcuc uuccuguucu ccagcgccua cuccaugaag       60

aagaacaucc ugaagauccu cauggacagc uacuccaagg agagcaagau ccagaccgug      120

cgccggguca ccuccgugag ccugcuggcc guguaccuca cgaugaacac cuccagccug      180

guccuggcca agcccaucga gaacaccaac gacaccucca ucaagaacgu ggagaagcuc      240

cgcaacgcgc ccaacgagga gaacagcaag aagguggagg acuccaagaa cgacaagguc      300

gagcacguga agaacaucga ggaggccaag guggagcagg ucgcccccga ggugaagagc      360

aaguccacgc ugcggagcgc cucccgccgg cgccggaagc gcaucgccaa caccaacagc      420

gagaaguacg acuucgagua ccugaacggc cucuccuaca ccgagcugac caaccugauc      480

aagaacauca aguggaacca gaucaacggg cucuucaacu acagcacggg cucccagaag      540

uucuucgggg acaagaaccg cgugcaggcg aucaucaacg cccugcagga gagcggccgg      600

accuacaccg ccaacgacau gaaggggauc gagaccuuca cggagguccu gcgcgccggc      660

uucuaccucg gcuacuacaa cgacgggcug uccuaccuga acgaccggaa cuuccaggac      720

aagugcaucc ccgcgaugau cgccauccag aagaacccca acuucaagcu cggcaccgcc      780

gugcaggacg aggugaucac cagccugggg aagcugaucg gcaacgccag cgccaacgcg      840

gaggucguga acaacugcgu gccgguccuc aagcaguucc gcgagaaccu gaaccaguac      900

gcccccgacu acgugaaggg gaccgccgug aacgagcuga ucaagggcau cgaguucgac      960

uucuccggcg ccgccuacga gaaggacguc aagacgaugc ccugguacgg gaagaucgac     1020

cccuucauca acgagcucaa ggcgcugggc cuguacggga acaucaccag cgccaccgag     1080

ugggccuccg acgugggcau cuacuaccuc agcaaguucg gccuguacuc caccaaccgg     1140

aacgacaucg ugcagagccu ggagaaggcc gucgacaugu acaaguacgg gaagaucgcc     1200

uucguggcga uggagcgcau cacgugggac uacgacggca ucggguccaa cggcaagaag     1260

gucgaccacg acaaguuccu cgacgacgcc gagaagcacu accugccgaa gaccuacacc     1320

uucgacaacg ggaccuucau cauccgggcc ggcgacaagg ugagcgagga gaagaucaag     1380

cgccuguacu gggccucccg ggaggugaag agccaguucc accgcgucgu gggcaacgac     1440

aaggcccucg agguggggaa cgcggacgac guccugacga ugaagaucuu caacuccccc     1500

gaggaguaca aguucaacac caacaucaac ggcgugagca ccgacaacgg gggccuguac     1560

aucgagccgc gggggaccuu cuacacguac gagcgcaccc cgcagcaguc caucuucagc     1620

cucgaggagc uguuccggca cgaguacacc cacuaccugc aggcccgcua ccucguggac     1680

ggccuguggg gccaggggcc guucuacgag aagaaccggc ugaccugguu cgacgagggc     1740

acggccgagu ucuucgccgg guccacccgc accagcggcg uccucccccg gaaguccauc     1800

cugggguacc uggcgaagga caagguggac caccgcuaca gccucaagaa gacccugaac     1860

uccggcuacg acgacagcga cuggauguuc uacaacuacg gcuucgccgu ggcccacuac     1920

cuguacgaga aggacaugcc cacguucauc aagaugaaca aggccauccu gaacaccgac     1980

gucaagagcu acgacgagau caucaagaag cucuccgacg acgccaacaa gaacaccgag     2040

uaccagaacc acauccagga gcuggcggac aaguaccagg gggccggcau cccccuggug     2100

agcgacgacu accucaagga ccacggguac aagaaggccu ccgaggugua cagcgagauc     2160

uccaaggccg ccagccugac caacaccucc gucacggcgg agaagagcca guacuucaac     2220

accuucaccc ugcgcggcac cuacacgggc gagaccucca agggggaguu caaggacugg     2280

gacgagauga gcaagaagcu cgacggcacc cuggaguccc uggccaagaa cagcuggucc     2340

ggguacaaga cccucacggc cuacuucacc aacuaccggg ugaccagcga caacaaggug     2400

caguacgacg ucguguucca cggcgugcug accgacaacg ccgacaucuc caacaacaag     2460

gccccgaucg cgaaggucac ggggcccagc accggcgccg ugggccgcaa caucgaguuc     2520

uccgggaagg acagcaagga cgaggacggc aagaucguga gcuacgacug ggacuucggg     2580

gacggcgcca ccucccgggg gaagaacagc guccacgccu acaagaaggc gggcaccuac     2640

aacgugacgc ugaaggugac cgacgacaag ggcgccaccg ccaccgaguc cuucacgauc     2700

gagaucaaga acgaggacac caccaccccc aucacgaagg agauggagcc caacgacgac     2760

aucaaggagg ccaacgggcc gaucgucgag ggcgugaccg ugaaggggga ccucaacggc     2820

agcgacgacg ccgacaccuu cuacuucgac gucaaggagg acggggacgu gaccaucgag     2880

cugcccuacu ccggcagcuc caacuucacg uggcuggugu acaaggaggg cgacgaccag     2940

aaccacaucg cgagcgggau cgacaagaac aacuccaagg ucggcaccuu caagagcacc     3000

aaggggcgcc acuacguguu caucuacaag cacgacuccg ccagcaacau cuccuacagc     3060

cucaacauca agggccuggg gaacgagaag cugaaggaga aggagaacaa cgacuccagc     3120

gacaaggcca ccgugauccc caacuucaac acgaccaugc agggcucccu ccugggcgac     3180

gacagccggg acuacuacuc cuucgagguc aaggaggagg gggaggugaa caucgagcug     3240

gacaagaagg acgaguucgg cgugaccugg acccuccacc ccgagagcaa caucaacgac     3300

cgcaucacgu acgggcaggu cgacggcaac aaggugagca acaaggugaa gcugcggccg     3360

ggcaaguacu accugcucgu cuacaaguac uccgggagcg gcaacuacga gcugcgcgug     3420

aacaaguga                                                             3429


<210>  222
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  222
augaacuucc ugaagaucau ccucaaccgc ggcaagacca ugaagcggaa gugccugagc       60

aagcgccuga ugcucgccau caccauggcc acgaucuuca ccgugaacuc cacccugccc      120

aucuacgcgg ccgucgacaa gaacaacgcc accgccgccg ugcagaacga gagcaagcgg      180

uacacggugu ccuaccugaa gacccucaac uacuacgacc uggucgaccu gcucgugaag      240

accgagaucg agaaccugcc ggaccuguuc caguacagcu ccgacgcgaa ggaguucuac      300

gggaacaaga cccgcaugag cuucaucaug gacgagaucg gccggcgcgc gccccaguac      360

acggagaucg accacaaggg gauccccacc cucguggagg ucgugcgggc cggcuucuac      420

cugggguucc acaacaagga gcugaacgag aucaacaagc gcuccuucaa ggagcgggug      480

auccccagca uccucgccau ccagaagaac ccgaacuuca agcugggcac cgagguccag      540

gacaagaucg uguccgccac cggccugcuc gccgggaacg agacggcccc gcccgaggug      600

gucaacaacu ucacccccau ccugcaggac ugcaucaaga acaucgaccg cuacgcccug      660

gacgaccuca agagcaaggc ccuguucaac gugcuggcgg ccccgaccua cgacaucacc      720

gaguaccucc gggccacgaa ggagaagccc gagaacaccc ccugguacgg caagaucgac      780

ggguucauca acgagcugaa gaagcuggcc cucuacggca agaucaacga caacaacucc      840

uggaucaucg acaacgggau cuaccacauc gcgccccugg gcaagcugca cagcaacaac      900

aagaucggca ucgagacccu caccgaggug augaaggucu acccguaccu guccaugcag      960

caccuccaga gcgccgacca gaucaagcgc cacuacgacu ccaaggacgc cgaggggaac     1020

aagauccccc uggacaaguu caagaaggag ggcaaggaga aguacugccc caagacguac     1080

accuucgacg acgggaaggu gaucaucaag gccggcgccc ggguggagga ggagaagguc     1140

aagcgccugu acugggccag caaggaggug aacucccagu ucuuccgggu guacggcauc     1200

gacaagcccc uggaggaggg gaacccggac gacauccuca ccauggucau cuacaacagc     1260

cccgaggagu acaagcugaa cuccgugcug uacggcuacg acaccaacaa cgggggcaug     1320

uacaucgagc ccgaggggac guucuucacc uacgagcgcg aggcgcagga gagcaccuac     1380

acccucgagg agcuguuccg gcacgaguac acgcacuacc ugcagggccg cuacgccgug     1440

cccggccagu gggggcggac caagcucuac gacaacgacc gccugaccug guacgaggag     1500

ggcggggccg agcuguucgc cggcagcacc cggacguccg ggauccuccc gcgcaagagc     1560

aucgucucca acauccacaa caccacccgc aacaaccggu acaagcugag cgacaccgug     1620

cacuccaagu acggcgccag cuucgaguuc uacaacuacg cgugcauguu cauggacuac     1680

auguacaaca aggacauggg cauccugaac aagcucaacg accuggccaa gaacaacgac     1740

gucgacgggu acgacaacua cauccgcgac cuguccagca acuacgcccu gaacgacaag     1800

uaccaggacc acaugcagga gcggaucgac aacuacgaga accucacggu gcccuucgug     1860

gccgacgacu accugguccg ccacgcguac aagaacccca acgagaucua cuccgagauc     1920

agcgaggugg ccaagcugaa ggacgccaag uccgagguga agaaguccca guacuucagc     1980

accuucaccc uccggggcag cuacaccggg ggcgccucca aggggaagcu ggaggaccag     2040

aaggccauga acaaguucau cgacgacagc cugaagaagc ucgacaccua cuccuggagc     2100

ggcuacaaga cgcugaccgc guacuucacc aacuacaagg ucgacuccag caaccgcgug     2160

accuacgacg uggucuucca cggcuaccug cccaacgagg gggacagcaa gaacucccuc     2220

ccguacggca agaucaacgg gacguacaag ggcaccgaga aggagaagau caaguucagc     2280

uccgagggca gcuucgaccc cgacgggaag aucguguccu acgaguggga cuucggcgac     2340

gggaacaaga gcaacgagga gaaccccgag cacuccuacg acaagguggg caccuacacc     2400

gucaagcuga aggugacgga cgacaagggg gagagcuccg ugagcaccac caccgccgag     2460

aucaaggacc uguccgagaa caagcucccc gucaucuaca ugcacgugcc caagagcggc     2520

gcccugaacc agaagguggu cuucuacggc aaggggacgu acgaccccga cggcuccauc     2580

gccggguacc agugggacuu cggcgacggg agcgacuucu ccagcgagca gaaccccucc     2640

cacguguaca ccaagaaggg cgaguacacc gugacccugc gggucaugga cagcagcggc     2700

cagauguccg agaagacgau gaagaucaag aucaccgacc cgguguaccc caucgggacc     2760

gagaaggagc ccaacaacag caaggagacc gccuccggcc ccaucgugcc ggggaucccc     2820

gucagcggca cgaucgagaa caccuccgac caggacuacu ucuacuucga cgugaucacc     2880

cccggggagg ugaagaucga caucaacaag cucggcuacg gcggggcgac cugggucgug     2940

uacgacgaga acaacaacgc cgugagcuac gccacggacg acggccagaa ccuguccggg     3000

aaguucaagg ccgacaagcc cggccgcuac uacauccacc uguacauguu caacgggagc     3060

uacaugccgu accggaucaa caucgagggc uccgucggcc gcuga                     3105


<210>  223
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  223
augaagcgca agugccugag caagcggcuc augcuggcca ucaccauggc caccaucuuc       60

acggugaacu ccacccugcc caucuacgcg gccgucgaca agaacaacgc caccgccgcc      120

gugcagaacg agagcaagcg cuacaccgug uccuaccuca agacgcugaa cuacuacgac      180

cuggucgacc uccuggugaa gaccgagauc gagaaccugc ccgaccucuu ccaguacagc      240

uccgacgcga aggaguucua cggcaacaag acccggauga gcuucaucau ggacgagauc      300

gggcgccggg ccccgcagua caccgagauc gaccacaagg gcauccccac gcugguggag      360

gucgugcgcg ccggguucua ccugggcuuc cacaacaagg agcucaacga gaucaacaag      420

cgguccuuca aggagcgcgu gauccccagc auccuggcca uccagaagaa cccgaacuuc      480

aagcugggga ccgaggucca ggacaagauc guguccgcga ccggccuccu ggccggcaac      540

gagaccgccc cgcccgaggu ggucaacaac uucacgccca uccugcagga cugcaucaag      600

aacaucgacc gguacgcccu cgacgaccug aagagcaagg cccuguucaa cgugcucgcg      660

gccccgaccu acgacaucac cgaguaccug cgcgccacca aggagaagcc cgagaacacg      720

ccgugguacg ggaagaucga cggcuucauc aacgagcuga agaagcucgc ccuguacggg      780

aagaucaacg acaacaacuc cuggaucauc gacaacggca ucuaccacau cgccccccug      840

gggaagcucc acagcaacaa caagaucggc aucgagaccc ugaccgaggu gaugaagguc      900

uacccguacc uguccaugca gcaccuccag agcgcggacc agaucaagcg gcacuacgac      960

uccaaggacg ccgagggcaa caagaucccc cuggacaagu ucaagaagga ggggaaggag     1020

aaguacugcc ccaagaccua cacguucgac gacggcaagg ugaucaucaa ggccggggcc     1080

cgcguggagg aggagaaggu caagcggcug uacugggcca gcaaggaggu gaacucccag     1140

uucuuccgcg uguacggcau cgacaagccc cucgaggagg gcaacccgga cgacauccug     1200

accaugguca ucuacaacag ccccgaggag uacaagcuga acuccgugcu cuacggguac     1260

gacaccaaca acggcgggau guacaucgag cccgagggca ccuucuucac guacgagcgg     1320

gaggcgcagg agagcaccua cacccuggag gagcuguucc gccacgagua cacccacuac     1380

cuccaggggc gguacgccgu gcccggccag uggggccgca cgaagcugua cgacaacgac     1440

cggcugaccu gguacgagga gggcggcgcc gagcucuucg ccgggagcac ccgcaccucc     1500

gggauccugc cgcggaagag caucgucucc aacauccaca acacgacccg caacaaccgc     1560

uacaagcuga gcgacaccgu gcacuccaag uacggggcca gcuucgaguu cuacaacuac     1620

gcgugcaugu ucauggacua cauguacaac aaggacaugg gcauccucaa caagcugaac     1680

gaccuggcca agaacaacga cgucgacggc uacgacaacu acauccggga ccuguccagc     1740

aacuacgccc ucaacgacaa guaccaggac cacaugcagg agcgcaucga caacuacgag     1800

aaccugaccg ugcccuucgu ggccgacgac uaccuggucc ggcacgcgua caagaacccc     1860

aacgagaucu acuccgagau cagcgaggug gccaagcuca aggacgccaa guccgaggug     1920

aagaagagcc aguacuucuc cacguucacc cugcgcggga gcuacaccgg cggggccucc     1980

aagggcaagc uggaggacca gaaggccaug aacaaguuca ucgacgacag ccucaagaag     2040

cuggacaccu acuccuggag cggguacaag acccugacgg cguacuucac caacuacaag     2100

gucgacucca gcaaccgggu gaccuacgac guggucuucc acggcuaccu ccccaacgag     2160

ggcgacagca agaacucccu gccguacggg aagaucaacg gcaccuacaa ggggacggag     2220

aaggagaaga ucaaguucag cuccgagggc agcuucgacc ccgacggcaa gaucgugucc     2280

uacgaguggg acuucgggga cggcaacaag agcaacgagg agaaccccga gcacuccuac     2340

gacaaggugg ggaccuacac cgucaagcug aaggugaccg acgacaaggg cgagagcucc     2400

gugagcacga ccaccgccga gaucaaggac cucuccgaga acaagcugcc cgucaucuac     2460

augcacgugc cgaagagcgg ggcccugaac cagaaggugg ucuucuacgg caagggcacc     2520

uacgaccccg acggguccau cgccggcuac cagugggacu ucggggacgg cagcgacuuc     2580

uccagcgagc agaaccccuc ccacguguac acgaagaagg gggaguacac cgugacccuc     2640

cgcgucaugg acagcagcgg ccagaugucc gagaagacca ugaagaucaa gaucacggac     2700

ccgguguacc ccaucggcac cgagaaggag cccaacaaca gcaaggagac cgccuccggg     2760

cccaucgugc cgggcauccc cgucagcggg accaucgaga acacguccga ccaggacuac     2820

uucuacuucg acgugaucac ccccggcgag gugaagaucg acaucaacaa gcugggguac     2880

ggcggcgcga ccugggucgu guacgacgag aacaacaacg ccgugagcua cgccaccgac     2940

gacgggcaga accuguccgg caaguucaag gccgacaagc ccgggcggua cuacauccac     3000

cucuacaugu ucaacggcag cuacaugccg uaccgcauca acaucgaggg guccgucggc     3060

cgguga                                                                3066


<210>  224
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  224
augaaguggg ugaccuucau cagccugcuc uuccuguucu ccagcgccua cuccgugcag       60

aacgagagca agcgcuacac cguguccuac cucaagacgc ugaacuacua cgaccugguc      120

gaccuccugg ugaagaccga gaucgagaac cugcccgacc ucuuccagua cagcuccgac      180

gcgaaggagu ucuacggcaa caagacccgg augagcuuca ucauggacga gaucgggcgc      240

cgggccccgc aguacaccga gaucgaccac aagggcaucc ccacgcuggu ggaggucgug      300

cgcgccgggu ucuaccuggg cuuccacaac aaggagcuca acgagaucaa caagcggucc      360

uucaaggagc gcgugauccc cagcauccug gccauccaga agaacccgaa cuucaagcug      420

gggaccgagg uccaggacaa gaucgugucc gcgaccggcc uccuggccgg caacgagacc      480

gccccgcccg agguggucaa caacuucacg cccauccugc aggacugcau caagaacauc      540

gaccgguacg cccucgacga ccugaagagc aaggcccugu ucaacgugcu cgcggccccg      600

accuacgaca ucaccgagua ccugcgcgcc accaaggaga agcccgagaa cacgccgugg      660

uacgggaaga ucgacggcuu caucaacgag cugaagaagc ucgcccugua cgggaagauc      720

aacgacaaca acuccuggau caucgacaac ggcaucuacc acaucgcccc ccuggggaag      780

cuccacagca acaacaagau cggcaucgag acccugaccg aggugaugaa ggucuacccg      840

uaccugucca ugcagcaccu ccagagcgcg gaccagauca agcggcacua cgacuccaag      900

gacgccgagg gcaacaagau cccccuggac aaguucaaga aggaggggaa ggagaaguac      960

ugccccaaga ccuacacguu cgacgacggc aaggugauca ucaaggccgg ggcccgcgug     1020

gaggaggaga aggucaagcg gcuguacugg gccagcaagg aggugaacuc ccaguucuuc     1080

cgcguguacg gcaucgacaa gccccucgag gagggcaacc cggacgacau ccugaccaug     1140

gucaucuaca acagccccga ggaguacaag cugaacuccg ugcucuacgg guacgacacc     1200

aacaacggcg ggauguacau cgagcccgag ggcaccuucu ucacguacga gcgggaggcg     1260

caggagagca ccuacacccu ggaggagcug uuccgccacg aguacaccca cuaccuccag     1320

gggcgguacg ccgugcccgg ccaguggggc cgcacgaagc uguacgacaa cgaccggcug     1380

accugguacg aggagggcgg cgccgagcuc uucgccggga gcacccgcac cuccgggauc     1440

cugccgcgga agagcaucgu cuccaacauc cacaacacga cccgcaacaa ccgcuacaag     1500

cugagcgaca ccgugcacuc caaguacggg gccagcuucg aguucuacaa cuacgcgugc     1560

auguucaugg acuacaugua caacaaggac augggcaucc ucaacaagcu gaacgaccug     1620

gccaagaaca acgacgucga cggcuacgac aacuacaucc gggaccuguc cagcaacuac     1680

gcccucaacg acaaguacca ggaccacaug caggagcgca ucgacaacua cgagaaccug     1740

accgugcccu ucguggccga cgacuaccug guccggcacg cguacaagaa ccccaacgag     1800

aucuacuccg agaucagcga gguggccaag cucaaggacg ccaaguccga ggugaagaag     1860

agccaguacu ucuccacguu cacccugcgc gggagcuaca ccggcggggc cuccaagggc     1920

aagcuggagg accagaaggc caugaacaag uucaucgacg acagccucaa gaagcuggac     1980

accuacuccu ggagcgggua caagacccug acggcguacu ucaccaacua caaggucgac     2040

uccagcaacc gggugaccua cgacgugguc uuccacggcu accuccccaa cgagggcgac     2100

agcaagaacu cccugccgua cgggaagauc aacggcaccu acaaggggac ggagaaggag     2160

aagaucaagu ucagcuccga gggcagcuuc gaccccgacg gcaagaucgu guccuacgag     2220

ugggacuucg gggacggcaa caagagcaac gaggagaacc ccgagcacuc cuacgacaag     2280

guggggaccu acaccgucaa gcugaaggug accgacgaca agggcgagag cuccgugagc     2340

acgaccaccg ccgagaucaa ggaccucucc gagaacaagc ugcccgucau cuacaugcac     2400

gugccgaaga gcggggcccu gaaccagaag guggucuucu acggcaaggg caccuacgac     2460

cccgacgggu ccaucgccgg cuaccagugg gacuucgggg acggcagcga cuucuccagc     2520

gagcagaacc ccucccacgu guacacgaag aagggggagu acaccgugac ccuccgcguc     2580

auggacagca gcggccagau guccgagaag accaugaaga ucaagaucac ggacccggug     2640

uaccccaucg gcaccgagaa ggagcccaac aacagcaagg agaccgccuc cgggcccauc     2700

gugccgggca uccccgucag cgggaccauc gagaacacgu ccgaccagga cuacuucuac     2760

uucgacguga ucacccccgg cgaggugaag aucgacauca acaagcuggg guacggcggc     2820

gcgaccuggg ucguguacga cgagaacaac aacgccguga gcuacgccac cgacgacggg     2880

cagaaccugu ccggcaaguu caaggccgac aagcccgggc gguacuacau ccaccucuac     2940

auguucaacg gcagcuacau gccguaccgc aucaacaucg agggguccgu cggccgguga     3000


<210>  225
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  225
augaaguggg ugaccuucau cagccugcuc uuccuguucu ccagcgccua cuccaugaag       60

cgcaagugcc ugagcaagcg gcucaugcug gccaucacca uggccaccau cuucacggug      120

aacuccaccc ugcccaucua cgcggccguc gacaagaaca acgccaccgc cgcccgccgg      180

cgccggaagc gcgugcagaa cgagagcaag cgcuacaccg uguccuaccu caagacgcug      240

aacuacuacg accuggucga ccuccuggug aagaccgaga ucgagaaccu gcccgaccuc      300

uuccaguaca gcuccgacgc gaaggaguuc uacggcaaca agacccggau gagcuucauc      360

auggacgaga ucgggcgccg ggccccgcag uacaccgaga ucgaccacaa gggcaucccc      420

acgcuggugg aggucgugcg cgccggguuc uaccugggcu uccacaacaa ggagcucaac      480

gagaucaaca agcgguccuu caaggagcgc gugaucccca gcauccuggc cauccagaag      540

aacccgaacu ucaagcuggg gaccgagguc caggacaaga ucguguccgc gaccggccuc      600

cuggccggca acgagaccgc cccgcccgag guggucaaca acuucacgcc cauccugcag      660

gacugcauca agaacaucga ccgguacgcc cucgacgacc ugaagagcaa ggcccuguuc      720

aacgugcucg cggccccgac cuacgacauc accgaguacc ugcgcgccac caaggagaag      780

cccgagaaca cgccguggua cgggaagauc gacggcuuca ucaacgagcu gaagaagcuc      840

gcccuguacg ggaagaucaa cgacaacaac uccuggauca ucgacaacgg caucuaccac      900

aucgcccccc uggggaagcu ccacagcaac aacaagaucg gcaucgagac ccugaccgag      960

gugaugaagg ucuacccgua ccuguccaug cagcaccucc agagcgcgga ccagaucaag     1020

cggcacuacg acuccaagga cgccgagggc aacaagaucc cccuggacaa guucaagaag     1080

gaggggaagg agaaguacug ccccaagacc uacacguucg acgacggcaa ggugaucauc     1140

aaggccgggg cccgcgugga ggaggagaag gucaagcggc uguacugggc cagcaaggag     1200

gugaacuccc aguucuuccg cguguacggc aucgacaagc cccucgagga gggcaacccg     1260

gacgacaucc ugaccauggu caucuacaac agccccgagg aguacaagcu gaacuccgug     1320

cucuacgggu acgacaccaa caacggcggg auguacaucg agcccgaggg caccuucuuc     1380

acguacgagc gggaggcgca ggagagcacc uacacccugg aggagcuguu ccgccacgag     1440

uacacccacu accuccaggg gcgguacgcc gugcccggcc aguggggccg cacgaagcug     1500

uacgacaacg accggcugac cugguacgag gagggcggcg ccgagcucuu cgccgggagc     1560

acccgcaccu ccgggauccu gccgcggaag agcaucgucu ccaacaucca caacacgacc     1620

cgcaacaacc gcuacaagcu gagcgacacc gugcacucca aguacggggc cagcuucgag     1680

uucuacaacu acgcgugcau guucauggac uacauguaca acaaggacau gggcauccuc     1740

aacaagcuga acgaccuggc caagaacaac gacgucgacg gcuacgacaa cuacauccgg     1800

gaccugucca gcaacuacgc ccucaacgac aaguaccagg accacaugca ggagcgcauc     1860

gacaacuacg agaaccugac cgugcccuuc guggccgacg acuaccuggu ccggcacgcg     1920

uacaagaacc ccaacgagau cuacuccgag aucagcgagg uggccaagcu caaggacgcc     1980

aaguccgagg ugaagaagag ccaguacuuc uccacguuca cccugcgcgg gagcuacacc     2040

ggcggggccu ccaagggcaa gcuggaggac cagaaggcca ugaacaaguu caucgacgac     2100

agccucaaga agcuggacac cuacuccugg agcggguaca agacccugac ggcguacuuc     2160

accaacuaca aggucgacuc cagcaaccgg gugaccuacg acguggucuu ccacggcuac     2220

cuccccaacg agggcgacag caagaacucc cugccguacg ggaagaucaa cggcaccuac     2280

aaggggacgg agaaggagaa gaucaaguuc agcuccgagg gcagcuucga ccccgacggc     2340

aagaucgugu ccuacgagug ggacuucggg gacggcaaca agagcaacga ggagaacccc     2400

gagcacuccu acgacaaggu ggggaccuac accgucaagc ugaaggugac cgacgacaag     2460

ggcgagagcu ccgugagcac gaccaccgcc gagaucaagg accucuccga gaacaagcug     2520

cccgucaucu acaugcacgu gccgaagagc ggggcccuga accagaaggu ggucuucuac     2580

ggcaagggca ccuacgaccc cgacgggucc aucgccggcu accaguggga cuucggggac     2640

ggcagcgacu ucuccagcga gcagaacccc ucccacgugu acacgaagaa gggggaguac     2700

accgugaccc uccgcgucau ggacagcagc ggccagaugu ccgagaagac caugaagauc     2760

aagaucacgg acccggugua ccccaucggc accgagaagg agcccaacaa cagcaaggag     2820

accgccuccg ggcccaucgu gccgggcauc cccgucagcg ggaccaucga gaacacgucc     2880

gaccaggacu acuucuacuu cgacgugauc acccccggcg aggugaagau cgacaucaac     2940

aagcuggggu acggcggcgc gaccuggguc guguacgacg agaacaacaa cgccgugagc     3000

uacgccaccg acgacgggca gaaccugucc ggcaaguuca aggccgacaa gcccgggcgg     3060

uacuacaucc accucuacau guucaacggc agcuacaugc cguaccgcau caacaucgag     3120

ggguccgucg gccgguga                                                   3138


<210>  226
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  226
augggcaccu ggauccuguu cgccugccuc cugggggccg cguucgccau gccccugccg       60

ccccaccccg gccaccccgg guacaucaac uucagcuacg aggugcucac cccgcugaag      120

ugguaccagu ccauccgccc gcccuacccc agcuacggcu acgagcccau gggcgggugg      180

cugcaccacc agaucauccc cguccucucc cagcagcacc cgcccacgca cacccugcag      240

ccgcaccacc acauccccgu ggugcccgcc cagcagcccg ucauccccca gcagcccaug      300

augcccgugc ccggccagca cagcaugacc ccgauccagc accaccagcc caaccugccc      360

ccgccggccc agcagcccua ccagccccag cccgugcagc cccagcccca ccagcccaug      420

cagccgcagc cgcccgucca ccccaugcag ccgcucccgc cccagccccc gcugccgccc      480

auguucccca ugcagccccu gccgcccaug cuccccgacc ugacccugga ggccuggccc      540

uccacggaca agaccaagcg ggaggaggug gacuga                                576


<210>  227
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  227
augccccugc cgccccaccc cggccacccc ggguacauca acuucagcua cgaggugcuc       60

accccgcuga agugguacca guccauccgc ccgcccuacc ccagcuacgg cuacgagccc      120

augggcgggu gguga                                                       135


<210>  228
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  228
augccccugc cgccccaccc cggccacccc ggguacauca acuucagcua cgaggugcuc       60

accccgcuga agugguacca guccauccgc ccgccgccca ugcuccccga ccugacccug      120

gaggccuggc ccuccacgga caagaccaag cgggaggagg uggacuga                   168


<210>  229
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  229
auggccguga uggccccgcg gacccugguc cuccugcuga gcggcgcgcu cgcccugacc       60

cagacguggg ccaugccccu gccgccccac cccggccacc ccggguacau caacuucagc      120

uacgaggugc ucaccccgcu gaagugguac caguccaucc gcccgcccua ccccagcuac      180

ggcuacgagc ccaugggcgg gugguga                                          207


<210>  230
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  230
auggccguga uggccccgcg gacccugguc cuccugcuga gcggcgcgcu cgcccugacc       60

cagacguggg ccaugccccu gccgccccac cccggccacc ccggguacau caacuucagc      120

uacgaggugc ucaccccgcu gaagugguac caguccaucc gcccgccgcc caugcucccc      180

gaccugaccc uggaggccug gcccuccacg gacaagacca agcgggagga gguggacuga      240


<210>  231
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  231
augggcaccu ggauccuguu cgccugccuc gugggggccg cguucgccau gccccugccg       60

ccccaccccg gccaccccgg guacaucaac uucagcuacg agguccugac cccgcucaag      120

ugguaccagu ccaugauccg cccgcccuac agcuccuacg gcuacgagcc caugggcggg      180

uggcugcacc accagaucau ccccguggug agccagcagc acccccugac gcacacccuc      240

cagucccacc accacauccc cgucgugccc gcccagcagc cgcgggugcg ccagcaggcc      300

cugaugcccg uccccggcca gcagagcaug acccccaccc agcaccacca gccgaaccug      360

ccccuccccg cccagcagcc cuuccagccg cagcccgugc agccccagcc ccaccagccg      420

augcagcccc agccgcccgu gcagcccaug cagccccugc ugccccagcc gccccucccg      480

cccauguucc cccugcggcc ccugccgccc auccuccccg accugcaccu ggaggcgugg      540

cccgccacgg acaagaccaa gcaggaggag gucgacuga                             579


<210>  232
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  232
augccccugc cgccccaccc cggccacccc ggguacauca acuucagcua cgagguccug       60

accccgcuca agugguacca guccaugauc cgcccgcccu acagcuccua cggcuacgag      120

cccaugggcg ggugguga                                                    138


<210>  233
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  233
augccccugc cgccccaccc cggccacccc ggguacauca acuucagcua cgagguccug       60

accccgcuca agugguacca guccaugauc cgcccgccgc ccauccuccc cgaccugcac      120

cuggaggcgu ggcccgccac ggacaagacc aagcaggagg aggucgacug a               171


<210>  234
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  234
auggccguga uggccccgcg gacccugguc cuccugcuga gcggcgcgcu cgcccugacc       60

cagacguggg ccaugccccu gccgccccac cccggccacc ccggguacau caacuucagc      120

uacgaggucc ugaccccgcu caagugguac caguccauga uccgcccgcc cuacagcucc      180

uacggcuacg agcccauggg cgggugguga                                       210


<210>  235
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  235
auggccguga uggccccgcg gacccugguc cuccugcuga gcggcgcgcu cgcccugacc       60

cagacguggg ccaugccccu gccgccccac cccggccacc ccggguacau caacuucagc      120

uacgaggucc ugaccccgcu caagugguac caguccauga uccgcccgcc gcccauccuc      180

cccgaccugc accuggaggc guggcccgcc acggacaaga ccaagcagga ggaggucgac      240

uga                                                                    243


<210>  236
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  236
augggcaccu ggauccuguu cgccugccuc cugggggccg cguucagcau gccccugccg       60

ccccaccccg gccaccccgg guacaucaac uucuccuacg aggugcucac cccgcugaag      120

ugguaccaga acaugauccg ccaccccuac acgagcuacg gcuacgagcc caugggcggg      180

uggcugcacc accagaucau ccccgucgug ucccagcaga ccccgcagag ccacgcccuc      240

cagccccacc accacauccc cauggugccc gcccagcagc cgggcauccc ccagcagccc      300

augaugcccc ugccggggca gcacuccaug acccccaccc agcaccacca gcccaaccug      360

ccccucccgg cccagcagcc cuuccagccc cagcccgucc agccgcagcc ccaccagccc      420

cugcagcccc agagcccgau gcaccccauc cagccccugc ucccgcagcc gccccugccc      480

ccgauguucu ccaugcagag ccugcucccc gaccugcccc uggaggccug gcccgcgacg      540

gacaagacca agcgggagga gguggacuga                                       570


<210>  237
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  237
augccccugc cgccccaccc cggccacccc ggguacauca acuucuccua cgaggugcuc       60

accccgcuga agugguacca gaacaugauc cgccaccccu acacgagcua cggcuacgag      120

cccaugggcg ggugguga                                                    138


<210>  238
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  238
augccccugc cgccccaccc cggccacccc ggguacauca acuucuccua cgaggugcuc       60

accccgcuga agugguacca gaacaugauc cgccacccca gccugcuccc cgaccugccc      120

cuggaggccu ggcccgcgac ggacaagacc aagcgggagg agguggacug a               171


<210>  239
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  239
auggccguga uggccccgcg gacccugguc cuccugcuga gcggcgcgcu cgcccugacc       60

cagacguggg ccaugccccu gccgccccac cccggccacc ccggguacau caacuucucc      120

uacgaggugc ucaccccgcu gaagugguac cagaacauga uccgccaccc cuacacgagc      180

uacggcuacg agcccauggg cgggugguga                                       210


<210>  240
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  240
auggccguga uggccccgcg gacccugguc cuccugcuga gcggcgcgcu cgcccugacc       60

cagacguggg ccaugccccu gccgccccac cccggccacc ccggguacau caacuucucc      120

uacgaggugc ucaccccgcu gaagugguac cagaacauga uccgccaccc cagccugcuc      180

cccgaccugc cccuggaggc cuggcccgcg acggacaaga ccaagcggga ggagguggac      240

uga                                                                    243


<210>  241
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  241
augggcaccu ggauccuguu cgccugccuc cugggggccg cguucagcau gccccugccg       60

ccccaccccg gccaccccgg guacaucaac uucuccuaca uccgccaccc guacaccagc      120

uacggcuacg agcccauggg cggguggcuc caccaccaga ucauccccgu ggucucccag      180

cagacgcccc agagccacgc ccugcagccg caccaccaca uccccauggu gcccgcccag      240

cagcccggca ucccgcagca gcccaugaug ccccugcccg ggcagcacuc caugaccccg      300

acccagcacc accagcccaa ccucccccug cccgcccagc agccguucca gccccagccc      360

gugcagcccc agccgcacca gccccugcag ccccagagcc ccaugcaccc gauccagccc      420

cuccugcccc agccgccccu gccgcccaug uucuccaugc agagccuccu gcccgaccug      480

ccccucgagg ccuggcccgc gaccgacaag acgaagcggg aggaggucga cuga            534


<210>  242
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  242
augggcaccu ggaucuucuu cgccugccug cucggggcca gccuggcgau gccccugccg       60

ccccaccccg gccaccccgg guacaucaac uucuccuacg aggugcucac gccccugaag      120

ugguaccaga acaugauccg ccaccccuac accagcuacg gcuacgagcc caugggcggg      180

uggcugcacc accagaucau ccccgucgug ucccagcaga ccccgcagag ccacgcccuc      240

cagccccacc accacauccc cauggugccc gcccagcagc cgggcauccc ccagcagccc      300

augaugcccc ugccggggca gcacuccaug acccccaccc agcaccacca gcccaaccug      360

ccccucccgg cccagcagcc cuuccagccc cagcccgucc agccgcagcc ccaccagccc      420

cugcagcccc agagcccgau gcaccccauc cagccccugc ucccgcagcc gccccugccg      480

cccauguucu ccaugcagag ccugcucccc gaccugcccc uggaggccug gcccgcgacg      540

gacaagacca agcgggagga gguggacuga                                       570


<210>  243
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  243
augggcaccu ggauccuguu cgccugccuc cugggggccg cguucagcau gccccugccg       60

ccccaccccg gccaccccgg guacaucaac uucuccuacg aggugcucac cccgcugaag      120

ugguaccaga acaugauccg ccaccccagc cugcuccccg accugccccu ggaggccugg      180

ccggccacgg acaagaccaa gcgggaggag gucgacuga                             219


<210>  244
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  244
augggcaccu ggauccuguu cgccugccuc cugggggccg cguucagcau gccccugccg       60

ccccaccccg gccaccccgg guacaucaac uucuccuacg aggaccucua ccuggaggcc      120

auccgcaucg accggaccgc cuucgugcug acgccccuca agugguacca gaacaugauc      180

cgccaccccu acaccagcua cggcuacgag cccaugggcg gguggcugca ccaccagauc      240

auccccgucg ugucccagca gaccccgcag agccacgccc ugcagcccca ccaccacauc      300

cccauggugc ccgcccagca gccgggcauc ccccagcagc ccaugaugcc ccucccgggg      360

cagcacucca ugacccccac gcagcaccac cagcccaacc ugccccugcc ggcgcagcag      420

cccuuccagc cccagcccgu ccagccgcag ccccaccagc cccuccagcc ccagagcccg      480

augcacccca uccagccccu gcugccgcag ccgccccugc cgcccauguu cuccaugcag      540

agccuccugc ccgaccuccc ccuggaggcc uggcccgcca ccgacaagac caagcgggag      600

gagguggacu ga                                                          612


<210>  245
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  245
augggcaccu ggauccuguu cgccugccuc cugggggccg cguucagcau gccccugccg       60

ccccaccccg gccaccccgg guacaucaac uucuccuacg aggugcucac cccgcugaag      120

ugguaccaga acaugauccg ccaccccacg ccccagagcc acgcccugca gccccaccac      180

cacaucccga ugguccccgc ccagcagccc ggcauccccc agcagccgau gaugccccuc      240

cccgggcagc acuccaugac ccccacccag caccaccagc cgaaccugcc ccugcccgcc      300

cagcagcccu uccagccgca gcccgugcag ccccagcccc accagccgcu ccagccccag      360

agccccaugc accccaucca gccgcugcug ccccagcccc cgcucccgcc cauguucucc      420

augcagagcc ugcugcccga ccucccccug gaggccuggc ccgcgaccga caagacgaag      480

cgggaggagg uggacuga                                                    498


<210>  246
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  246
augccccugc cgccccaccc cggccacccc ggguacauca acuucagcua cgaggugcuc       60

accccgcuga agugguacca gaacaugauc cgccaccccu acaccuccua cggcuacgag      120

cccaugggcg gguggcugca ccaccagauc auccccgucg ugagccagca gacgccgcag      180

ucccacgccc uccagcccca ccaccacauc cccauggugc ccgcccagca gcccgggauc      240

ccccagcagc ccaugaugcc ccugccgggc cagcacagca ugacccccac ccagcaccac      300

cagcccaacc ugccccuccc ggcgcagcag cccuuccagc cccagcccgu ccagccgcag      360

ccccaccagc cccugcagcc ccaguccccg augcacccca uccagccccu gcucccgcag      420

ccgccccugc cgcccauguu cagcaugcag ucccugcucc ccgaccugcc ccuggaggcc      480

uggcccgcca ccgacaagac gaagcgggag gagguggacu ga                         522


<210>  247
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  247
augcccggcg uggcccgccu gccgcuccug cuggggcucc ugcugcuccc ccggcccggc       60

cgcccccugg accuggccga cuacaccuac gaccucgccg aggaggacga cagcgagccg      120

cugaacuaca aggaccccug caaggccgcc gccuuccugg gggacaucgc ccucgacgag      180

gaggaccugc gggcguucca gguccagcag gccguggacc ugcgccggca caccgcccgc      240

aaguccagca ucaaggccgc ggugcccggc aacacgucca cccccagcug ccaguccacc      300

aacgggcagc cgcagcgggg cgccugcggc cgcuggcggg ggcgcagccg gucccgccgg      360

gccgccacca gccgccccga gcgggucugg cccgacggcg ugauccccuu cgugaucggg      420

ggcaacuuca cgggguccca gcgcgccguc uuccggcagg cgaugcgcca cugggagaag      480

cacacgugcg ugaccuuccu cgagcggacc gacgaggaca gcuacaucgu guucaccuac      540

cgcccgugcg gcugcugcuc cuacgucggc cggcgcgggg gcgggcccca ggccaucagc      600

aucggcaaga acugcgacaa guucggcauc guggugcacg agcuggggca cgucgugggc      660

uucuggcacg agcacacccg ccccgaccgg gaccgccacg uguccaucgu ccgggagaac      720

auccagcccg ggcaggagua caacuuccug aagauggagc cgcaggaggu ggagagccuc      780

ggcgagaccu acgacuucga cuccaucaug cacuacgccc gcaacaccuu cagccggggg      840

aucuuccugg acacgaucgu gcccaaguac gaggucaacg gcgugaagcc gcccaucggc      900

cagcgcaccc ggcuguccaa gggggacauc gcccaggccc gcaagcucua caagugcccc      960

gcgugcggcg agacccugca ggacagcacc gggaacuucu ccagccccga guaccccaac     1020

ggcuacagcg cccacaugca cugcgugugg cggaucuccg ucacgcccgg ggagaagauc     1080

auccugaacu ucaccagccu cgaccuguac cgcucccggc ugugcuggua cgacuacgug     1140

gaggugcgcg acggcuucug gcggaaggcc ccgcuccgcg gccgguucug cgggagcaag     1200

cugcccgagc ccaucgucuc caccgacagc cgccuguggg uggaguuccg guccagcucc     1260

aacugggucg gcaagggguu cuucgccgug uacgaggcca ucugcggcgg ggacgugaag     1320

aaggacuacg gccacaucca gagccccaac uacccggacg acuaccgccc cuccaagguc     1380

ugcaucuggc ggauccaggu gagcgagggc uuccacgugg ggcucaccuu ccaguccuuc     1440

gagaucgagc gccacgacag cugcgcguac gacuaccugg agguccgcga cggccacucc     1500

gagagcucca cgcugaucgg gcgguacugc ggcuacgaga agcccgacga caucaagagc     1560

accuccagcc gccucuggcu gaaguucgug agcgacggcu ccaucaacaa ggccggguuc     1620

gccgugaacu ucuucaagga ggucgacgag ugcagccggc cgaaccgcgg cgggugcgag     1680

cagcggugcc ugaacacccu cggcuccuac aagugcagcu gcgaccccgg guacgagcug     1740

gcccccgaca agcgccggug cgaggccgcg ugcggcggcu uccugaccaa gcucaacggg     1800

uccaucacga gccccggcug gccgaaggag uacccgccca acaagaacug caucuggcag     1860

cugguggccc ccacccagua ccgcaucucc cugcaguucg acuucuucga gaccgagggg     1920

aacgacgugu gcaaguacga cuucgucgag gugcggagcg gccucaccgc cgacuccaag     1980

cugcacggga aguucugcgg cagcgagaag cccgagguga ucacguccca guacaacaac     2040

augcgcgucg aguucaagag cgacaacacc guguccaaga agggcuucaa ggcccacuuc     2100

uucagcgaca aggacgagug cuccaaggac aacgggggcu gccagcagga cugcgugaac     2160

accuucggga gcuacgagug ccagugccgg uccggcuucg uccugcacga caacaagcac     2220

gacugcaagg aggcggggug cgaccacaag gugaccagca cgagcggcac caucaccucc     2280

cccaacuggc ccgacaagua ccccagcaag aaggagugca ccugggccau cuccagcacg     2340

ccgggccacc gcgugaagcu caccuucaug gagauggaca ucgaguccca gcccgagugc     2400

gccuacgacc accuggaggu cuucgacggg cgggacgcca aggcccccgu gcugggccgc     2460

uucugcggga gcaagaagcc cgagccggug cucgcgaccg gcucccggau guuccugcgc     2520

uucuacagcg acaacuccgu ccagcggaag ggguuccagg ccagccacgc caccgagugc     2580

ggcggccagg ugcgcgccga cgugaagacc aaggaccugu acucccacgc ccaguucggg     2640

gacaacaacu accccggcgg ggucgacugc gaguggguga ucguggcgga ggagggcuac     2700

ggcgucgagc ugguguucca gacguucgag guggaggagg agaccgacug cggguacgac     2760

uacauggagc uguucgacgg cuacgacagc accgcgcccc ggcucgggcg cuacugcggc     2820

uccgggcccc cggaggaggu cuacagcgcc ggcgacuccg ugcuggugaa guuccacagc     2880

gacgacacca ucacgaagaa gggcuuccac cuccgguaca ccuccaccaa guuccaggac     2940

acccugcaca gccgcaagug a                                               2961


<210>  248
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  248
augguggccg gcacccgcug ccugcucgcc cugcugcucc cccagguccu gcucgggggc       60

gcggccgggc uggugccgga gcugggccgg cgcaaguucg ccgccgccag cuccgggcgg      120

cccagcuccc agcccagcga cgaggugcug uccgaguucg agcuccgccu gcugagcaug      180

uucggccuca agcagcggcc caccccgucc cgcgacgcgg ucgugccgcc cuacaugcug      240

gaccuguacc ggcgccacag cggccagccc gggucccccg cccccgacca ccggcucgag      300

cgcgccgcca gccgggcgaa cacggugcgc uccuuccacc acgaggagag ccuggaggag      360

cugcccgaga ccuccggcaa gaccacccgg cgcuucuucu ucaaccucag cuccaucccc      420

acggaggagu ucaucaccag cgccgagcug caggucuucc gggagcagau gcaggacgcc      480

cuggggaaca acuccagcuu ccaccaccgc aucaacaucu acgagaucau caagccggcc      540

accgccaacu ccaaguuccc cgugacccgg cuccuggaca cgcgccuggu gaaccagaac      600

gcgagccggu gggagagcuu cgacgucacc cccgccguga ugcgcuggac cgcccagggc      660

cacgccaacc acggguucgu ggucgaggug gcccaccucg aggagaagca gggcgugucc      720

aagcggcacg uccgcaucag ccgcucccug caccaggacg agcacagcug gucccagauc      780

cggccccugc ucgugaccuu cggccacgac gggaagggcc acccgcugca caagcgcgag      840

aagcggcagg cgaagcacaa gcagcgcaag cggcucaaga gcuccugcaa gcgccacccc      900

cuguacgugg acuucagcga cgucgggugg aacgacugga ucguggcccc gcccggcuac      960

cacgccuucu acugccacgg cgagugcccc uucccccugg ccgaccaccu gaacuccacg     1020

aaccacgcca ucgugcagac ccucgucaac agcgugaacu ccaagauccc caaggcgugc     1080

ugcgugccca ccgagcugag cgccaucucc augcuguacc ucgacgagaa cgagaagguc     1140

gugcugaaga acuaccagga cauggucgug gaggggugcg gcugccggug a              1191


<210>  249
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  249
augauccccg gcaaccgcau gcugauggug guccuccugu gccaggugcu gcucgggggc       60

gccagccacg ccucccugau cccggagacc gggaagaaga agguggcgga gauccagggc      120

cacgccgggg gccggcgcag cggccagucc cacgagcugc uccgggacuu cgaggccacc      180

cugcugcaga uguucgggcu ccgccggcgc ccccagccca gcaaguccgc cgucaucccc      240

gacuacaugc gggaccugua ccgccugcag agcggcgagg aggaggagga gcagauccac      300

uccacggggc ucgaguaccc ggagcggccc gccagccgcg cgaacaccgu gcgguccuuc      360

caccacgagg agcaccugga gaacaucccc ggcaccagcg agaacuccgc cuuccgcuuc      420

cuguucaacc ucagcuccau ccccgagaac gaggugauca gcuccgccga gcugcggcug      480

uuccgcgagc aggucgacca ggggccggac ugggagcggg gcuuccaccg caucaacauc      540

uacgagguga ugaagccgcc cgccgaggug guccccggcc accucaucac ccggcugcug      600

gacacgcgcc ucgugcacca caacgugacc cggugggaga ccuucgacgu cagccccgcg      660

gugcugcgcu ggacccggga gaagcagccc aacuacgggc uggccaucga ggugacgcac      720

cuccaccaga cccgcaccca ccagggccag cacguccgca ucucccggag ccugccccag      780

ggguccggca acugggccca gcugcgcccc cuccugguga ccuucggcca cgacgggcgg      840

ggccacgccc ugacgcgccg gcgccgggcc aagcgcagcc cgaagcacca cagccagcgg      900

gcgcgcaaga agaacaagaa cugccggcgc cacucccucu acguggacuu cagcgacguc      960

ggguggaacg acuggaucgu ggccccgccc ggcuaccagg ccuucuacug ccacggggac     1020

ugccccuucc cccuggccga ccaccugaac uccaccaacc acgccaucgu gcagacccuc     1080

gucaacagcg ugaacuccag cauccccaag gcgugcugcg ugcccaccga gcuguccgcc     1140

aucagcaugc uguaccucga cgaguacgac aaggucgugc ugaagaacua ccaggagaug     1200

gucguggagg gcugcggcug ccgguga                                         1227


<210>  250
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  250
augcccggcc uggggcgccg ggcccagugg cucugcuggu gguggggccu gcugugcagc       60

ugcugcgggc cgccgccccu ccggccgccc cugcccgccg cggccgccgc cgccgcgggc      120

gggcagcugc ucggcgacgg cggguccccc ggccggaccg agcagccccc gcccagcccc      180

caguccagcu ccggguuccu guaccgccgg cugaagaccc aggagaagcg cgagaugcag      240

aaggagaucc ucagcgugcu gggccugccc caccggcccc gcccccucca cgggcugcag      300

cagccccagc ccccggcccu gcggcagcag gaggagcagc agcagcagca gcagcucccc      360

cgcggcgagc ccccgcccgg ccggcugaag uccgcgcccc uguucaugcu cgaccuguac      420

aacgcccuga gcgccgacaa cgacgaggac ggggccuccg agggcgagcg ccagcagagc      480

uggccccacg aggccgccuc cagcucccag cggcgccagc ccccgcccgg ggccgcgcac      540

ccccucaacc gcaagagccu gcuggccccc ggcuccggca gcgggggcgc cuccccgcuc      600

acgagcgccc aggacuccgc cuuccugaac gacgcggaca uggucaugag cuucgugaac      660

cugguggagu acgacaagga guucagcccc cgccagcggc accacaagga guucaaguuc      720

aaccucuccc agauccccga gggggagguc gugaccgccg ccgaguuccg caucuacaag      780

gacugcguga ugggcagcuu caagaaccag accuuccuga ucuccaucua ccagguccug      840

caggagcacc agcaccggga cagcgaccuc uuccugcugg acacccgcgu ggugugggcc      900

uccgaggagg gguggcucga guucgacauc acggccacca gcaaccugug ggucgugacc      960

ccgcagcaca acaugggccu gcagcucucc guggucaccc gggacggcgu gcacgugcac     1020

ccccgcgcgg ccgggcuggu cggccgcgac gggcccuacg acaagcagcc cuucauggug     1080

gccuucuuca aggugagcga gguccacgug cggacgaccc gcuccgccag cucccggcgc     1140

cggcagcaga gccgcaaccg guccacccag agccaggacg uggcccgcgu cuccagcgcg     1200

uccgacuaca acagcuccga gcugaagacc gccugccgga agcacgagcu cuacgugagc     1260

uuccaggacc ugggcuggca ggacuggauc aucgccccga agggguacgc cgcgaacuac     1320

ugcgacggcg agugcagcuu cccccugaac gcccacauga acgccacgaa ccacgccauc     1380

gugcagaccc ucguccaccu gaugaacccc gaguacgugc ccaagccgug cugcgccccc     1440

accaagcuga acgcgaucuc cguccucuac uucgacgaca acagcaacgu gauccugaag     1500

aaguaccgca acaugguggu ccgggccugc ggcugccacu ga                        1542


<210>  251
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  251
augcacgugc gcagccugcg ggccgccgcg ccccacuccu ucgucgcccu cugggccccg       60

cuguuccugc uccgcagcgc ccuggccgac uucucccugg acaacgaggu gcacagcucc      120

uucauccacc ggcgccuccg gagccaggag cgccgggaga ugcagcgcga gauccugucc      180

auccugggcc ucccccaccg gccccgcccc caccuccagg ggaagcacaa cagcgcgccg      240

auguucaugc uggaccugua caacgccaug gccguggagg agggcggggg ccccgggggc      300

cagggcuucu ccuaccccua caaggccguc uucagcaccc aggggccccc gcuggcgucc      360

cugcaggaca gccacuuccu caccgacgcc gacaugguga uguccuucgu gaaccugguc      420

gagcacgaca aggaguucuu ccacccccgg uaccaccacc gcgaguuccg guucgaccug      480

agcaagaucc ccgagggcga ggccgugacg gccgccgagu uccgcaucua caaggacuac      540

auccgggagc gcuucgacaa cgagaccuuc cggaucuccg uguaccaggu ccuccaggag      600

caccuggggc gcgagagcga ccuguuccuc cuggacuccc ggacccugug ggcgagcgag      660

gagggcuggc ucguguucga caucaccgcc acguccaacc acuggguggu caacccccgc      720

cacaaccugg ggcugcagcu cagcguggag acccuggacg gccagagcau caacccgaag      780

cuggccggcc ucaucgggcg gcacggcccc cagaacaagc agcccuucau gguggccuuc      840

uucaaggcca ccgaggucca cuuccgcucc auccgcagca ccggguccaa gcagcggagc      900

cagaaccgcu ccaagacgcc caagaaccag gaggcgcugc ggauggccaa cguggccgag      960

aacagcucca gcgaccagcg ccaggccugc aagaagcacg agcuguacgu guccuuccgg     1020

gaccucggcu ggcaggacug gaucaucgcc ccggagggcu acgcggccua cuacugcgag     1080

ggggagugcg ccuucccccu gaacagcuac augaacgcca ccaaccacgc caucguccag     1140

acccuggugc acuucaucaa ccccgagacc gugcccaagc cgugcugcgc gcccacgcag     1200

cucaacgcca ucuccguccu guacuucgac gacagcucca acgugauccu gaagaaguac     1260

cgcaacaugg ugguccgggc cugcggcugc cacuga                               1296


<210>  252
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  252
augaaggcca gcgccgcgcu gcucugccug cugcucaccg ccgccgccuu cagcccccag       60

ggccuggccc agccgguggg gaucaacacc uccacgaccu gcugcuaccg cuucaucaac      120

aagaagaucc ccaagcagcg gcuggagucc uaccgccgga ccaccagcuc ccacugcccc      180

cgcgaggcgg ucaucuucaa gacgaagcuc gacaaggaga ucugcgccga ccccacccag      240

aagugggugc aggacuucau gaagcaccug gacaagaaga cccagacccc gaagcuguga      300


<210>  253
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  253
augcugcuca cccugaucau ccugcucccc guggucagca aguucuccuu cgugagccug       60

uccgcgcccc agcacuggag cugccccgag ggcacccugg ccgggaacgg caacuccacg      120

ugcguggggc ccgcccccuu ccucaucuuc agccacggca acuccaucuu ccgcaucgac      180

accgagggga ccaacuacga gcagcugguc guggacgccg gcgugagcgu caucauggac      240

uuccacuaca acgagaagcg gaucuacugg guggaccugg agcgccagcu ccugcagcgg      300

guguuccuga acggcucccg ccaggagcgg gucugcaaca ucgagaagaa cgugagcggg      360

auggccauca acuggaucaa cgaggaggug aucuggucca accagcagga gggcaucauc      420

accgucacgg acaugaaggg gaacaacagc cacauccucc uguccgcccu gaaguacccg      480

gccaacgugg cgguggaccc cgucgagcgc uucaucuucu ggagcuccga gguggccggc      540

agccucuacc gggccgaccu ggacggggug ggcgucaagg cccugcucga gaccuccgag      600

aagaucaccg cggugagccu ggacgugcug gacaagcgcc ucuucuggau ccaguacaac      660

cgggagggcu ccaacagccu gaucugcagc ugcgacuacg acgggggcuc cguccacauc      720

agcaagcacc ccacccagca caaccuguuc gccauguccc ucuucgggga ccgcaucuuc      780

uacagcacgu ggaagaugaa gaccaucugg aucgccaaca agcacaccgg caaggacaug      840

gugcggauca accugcacuc cagcuucgug ccccugggcg agcucaaggu cgugcacccg      900

cuggcccagc ccaaggccga ggacgacacc ugggagcccg agcagaagcu gugcaagcuc      960

cgcaagggga acugcuccag cacggucugc ggccaggacc ugcaguccca ccugugcaug     1020

ugcgcggagg gguacgcccu cagccgggac cgcaaguacu gcgaggacgu gaacgagugc     1080

gccuucugga accacggcug cacccugggg ugcaagaaca cccccggcuc cuacuacugc     1140

acgugcccgg ugggcuucgu ccugcucccc gacgggaagc ggugccacca gcuggugagc     1200

ugcccccgca acguguccga gugcagccac gacugcgucc ugaccuccga gggcccccuc     1260

ugcuucugcc cggaggggag cgugcuggag cgggacggca agaccugcuc cgggugcagc     1320

ucccccgaca acggcggcug cagccagcug ugcgugcccc ucagccccgu cuccugggag     1380

ugcgacugcu ucccggggua cgaccugcag cuggacgaga aguccugcgc cgccagcggc     1440

ccccagcccu uccuccuguu cgcgaacagc caggacaucc gccacaugca cuucgacggg     1500

accgacuacg gcacccugcu cucccagcag auggggaugg uguacgcccu ggaccacgac     1560

cccguggaga acaagaucua cuucgcccac acggcccuga aguggaucga gcgggccaac     1620

auggacggca gccagcgcga gcggcugauc gaggagggcg ucgacgugcc ggaggggcuc     1680

gcgguggacu ggaucggccg ccgcuucuac uggaccgacc gggggaaguc ccugaucggc     1740

cgcagcgacc ugaacggcaa gcgguccaag aucaucacca aggagaacau cagccagccc     1800

cgcgggaucg ccguccaccc cauggccaag cgccucuucu ggaccgacac gggcaucaac     1860

ccccggaucg aguccagcuc ccugcagggg cugggccggc ucgugaucgc cagcuccgac     1920

cugaucuggc cgagcgggau caccaucgac uuccugaccg acaagcucua cuggugcgac     1980

gccaagcagu ccgugaucga gauggcgaac cuggacggca gcaagcgccg gcgccugacc     2040

cagaacgacg ucggccaccc cuucgccgug gccguguucg aggacuacgu cugguucagc     2100

gacugggcca ugcccuccgu gaugcgggug aacaagcgca cggggaagga ccggguccgc     2160

cuccagggca gcaugcugaa gccguccagc cugguggugg uccacccccu cgcgaagccc     2220

ggggccgacc ccugccugua ccagaacggc gggugcgagc acaucugcaa gaagcggcug     2280

ggcaccgccu ggugcuccug ccgcgagggc uucaugaagg ccagcgacgg gaagaccugc     2340

cucgcccugg acggccacca gcugcucgcc gggggcgagg uggaccugaa gaaccaggug     2400

accccgcugg acauccucuc caagacgcgg gucagcgagg acaacaucac cgagucccag     2460

cacaugcugg uggccgagau cauggugagc gaccaggacg acugcgcccc cgucgggugc     2520

uccauguacg cccgcugcau cagcgagggc gaggacgcga ccugccagug ccugaagggc     2580

uucgcggggg acggcaagcu cugcuccgac aucgacgagu gcgagauggg ggugcccgug     2640

ugcccgccgg ccagcuccaa gugcaucaac accgagggcg gguacgucug ccggugcagc     2700

gagggcuacc agggcgacgg gauccacugc cuggacaucg acgagugcca gcugggcgag     2760

cacuccugcg gggagaacgc cagcugcacg aacaccgagg gcggcuacac gugcaugugc     2820

gccgggcgcc ucuccgagcc cggccugauc ugccccgaca gcacgccccc gccccaccuc     2880

cgcgaggacg accaccacua cagcgugcgg aacuccgaca gcgagugccc ccugucccac     2940

gacggguacu gccugcacga cggcgugugc auguacaucg aggcccugga caaguacgcg     3000

ugcaacugcg ucguggggua caucggcgag cgcugccagu accgggaccu caaguggugg     3060

gagcugcgcc acgccggcca cgggcagcag cagaagguga ucgucguggc cgugugcguc     3120

guggugcugg ucaugcuccu gcugcucagc cuguggggcg cccacuacua ccggacccag     3180

aagcugcucu ccaagaaccc caagaacccg uacgaggaga gcucccgcga cgugcggagc     3240

cgccggcccg cggacaccga ggacgggaug uccagcugcc cccagcccug guucgugguc     3300

aucaaggagc accaggaccu gaagaacggc gggcagccgg uggccggcga ggacggccag     3360

gccgccgacg gguccaugca gcccaccagc uggcgccagg agccccagcu gugcggcaug     3420

gggaccgagc agggcugcug gauccccguc uccagcgaca agggguccug cccccaggug     3480

auggagcgga gcuuccacau gcccuccuac ggcacccaga cccucgaggg cgggguggag     3540

aagccccaca gccugcuguc cgccaacccg cucuggcagc agcgcgcgcu ggacccgccc     3600

caccagaugg agcugaccca guga                                            3624


<210>  254
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  254
augaccgccg gccgccggau ggagaugcug ugcgccgggc gcgugcccgc gcuccugcug       60

ugccucggcu uccaccuccu gcaggccguc cugagcacca cggugauccc guccugcauc      120

cccggggaga gcuccgacaa cugcaccgcc cuggugcaga ccgaggacaa cccccggguc      180

gcccagguga gcaucaccaa gugcuccagc gacaugaacg gcuacugccu gcacgggcag      240

ugcaucuacc ucguggacau gucccagaac uacugccgcu gcgaggucgg cuacacgggc      300

gugcggugcg agcacuucuu ccugaccgug caccagcccc ugagcaagga guacgucgcc      360

cucaccguga uccugaucau ccuguuccuc aucaccgugg ucggguccac guacuacuuc      420

ugccgcuggu accggaaccg caagagcaag gagccgaaga aggaguacga gcgggugacc      480

uccggcgacc ccgagcugcc ccagguguga                                       510


<210>  255
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  255
auggccgagg gcgagaucac caccuucacg gcccugaccg agaaguucaa ccugcccccg       60

gggaacuaca agaagcccaa gcuccuguac ugcagcaacg gcgggcacuu ccuccgcauc      120

cugcccgacg gcaccgugga cgggacccgg gaccgcuccg accagcacau ccagcugcag      180

cucagcgcgg aguccgucgg cgagguguac aucaagagca cggagaccgg ccaguaccug      240

gccauggaca ccgacgggcu gcucuacggc ucccagaccc ccaacgagga gugccuguuc      300

cuggagcggc ucgaggagaa ccacuacaac acguacauca gcaagaagca cgccgagaag      360

aacugguucg uggggcugaa gaagaacggc uccugcaagc gcgggccgcg gacccacuac      420

ggccagaagg ccauccuguu ccucccccug cccgucagcu ccgacuga                   468


<210>  256
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  256
auggugggcg ucgggggcgg ggacguggag gacgugaccc cgcgcccggg cgggugccag       60

aucagcggcc ggggcgcccg cgggugcaac ggcauccccg gggccgcggc cugggaggcc      120

gcccugcccc ggcgccggcc ccgccggcac ccguccguca acccccgcag ccgggccgcg      180

ggcagccccc gcacccgggg gcgccggacg gaggagcgcc ccuccggcuc ccggcucggc      240

gaccgcgggc ggggccgcgc ccugcccggg ggccggcugg gcgggcgcgg ccgggggcgc      300

gcccccgagc gcgugggcgg gcggggccgc ggccggggga ccgccgcgcc ccgcgccgcc      360

cccgccgccc ggggcagccg cccggggccc gcgggcacca uggccgccgg guccaucacc      420

acgcuccccg cccugcccga ggacggcggc agcggggccu ucccgcccgg ccacuucaag      480

gaccccaagc ggcuguacug caagaacggg ggcuucuucc uccgcaucca ccccgacggg      540

cggguggacg gcguccgcga gaaguccgac ccgcacauca agcugcagcu gcaggcggag      600

gagcggggcg uggugagcau caaggggguc ugcgccaacc gcuaccucgc caugaaggag      660

gacggccggc ugcuggccuc caagugcgug accgacgagu gcuucuucuu cgagcgccuc      720

gagagcaaca acuacaacac cuaccggucc cgcaaguaca ccagcuggua cguggcccug      780

aagcggacgg ggcaguacaa gcugggcucc aagaccggcc ccgggcagaa ggcgauccuc      840

uuccugccca ugagcgccaa guccuga                                          867


<210>  257
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  257
augcacaagu ggauccugac cuggauccuc cccacccugc uguaccgcag cugcuuccac       60

aucaucugcc ucgugggcac gaucucccug gccugcaacg acaugacccc ggagcagaug      120

gccaccaacg ucaacugcag cucccccgag cggcacaccc gcagcuacga cuacauggag      180

ggcggggaca uccgggugcg ccggcuguuc ugccgcacgc agugguaccu ccggaucgac      240

aagcgcggga aggugaaggg cacccaggag augaagaaca acuacaacau cauggagauc      300

cggaccgucg cgguggggau cguggccauc aagggcgucg aguccgaguu cuaccuggcc      360

augaacaagg agggcaagcu guacgccaag aaggagugca acgaggacug caacuucaag      420

gagcucaucc uggagaacca cuacaacacc uacgccagcg cgaaguggac gcacaacggg      480

ggcgagaugu ucguggcccu gaaccagaag gggauccccg ugcgcggcaa gaagaccaag      540

aaggagcaga agaccgccca cuuccucccc auggccauca ccuga                      585


<210>  258
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  258
augaagcugc uccccagcgu gguccugaag cuguuccucg ccgccgugcu guccgcgcug       60

gugaccggcg agagccucga gcggcugcgg cgcgggcugg ccgccggcac cuccaacccg      120

gacccgccca cggucagcac cgaccagcuc cugccccucg ggggcgggcg ggaccgcaag      180

gugcgggacc ugcaggaggc cgaccuggac cugcuccgcg ugacccuguc cagcaagccc      240

caggcccugg cgacccccaa caaggaggag cacggcaagc ggaagaagaa gggcaagggg      300

cucggcaaga agcgcgaccc cugccugcgg aaguacaagg acuucugcau ccacggggag      360

ugcaaguacg ucaaggagcu gcgcgccccc uccugcaucu gccacccggg cuaccacggg      420

gagcggugcc acggccucag ccugcccgug gagaaccgcc uguacacgua cgaccacacc      480

accauccucg ccguggucgc cguggugcug uccagcgucu gccugcucgu gaucgugggc      540

cugcugaugu uccgguacca ccgccgcggg ggcuacgacg ucgagaacga ggagaaggug      600

aagcucggga ugaccaacuc ccacuga                                          627


<210>  259
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  259
auguggguga ccaagcugcu ccccgcccug cugcuccagc acguccugcu gcaccuccug       60

cugcucccga ucgccauccc cuacgcggag ggccagcgca agcggcgcaa caccauccac      120

gaguucaaga aguccgccaa gacgacccug aucaagaucg accccgcccu gaagaucaag      180

accaagaagg ugaacaccgc cgaccagugc gccaaccggu gcacgcgcaa caaggggcuc      240

cccuucacgu gcaaggcguu cguguucgac aaggcccgga agcagugccu gugguucccg      300

uucaacagca ugagcuccgg cgucaagaag gaguucgggc acgaguucga ccuguacgag      360

aacaaggacu acauccgcaa cugcaucauc ggcaaggggc ggagcuacaa gggcaccgug      420

uccaucacca agagcggcau caagugccag cccuggucca gcaugauccc ccacgagcac      480

uccuuccucc ccagcuccua ccgcgggaag gaccugcagg agaacuacug ccggaacccg      540

cgcggcgagg agggcgggcc cuggugcuuc accagcaacc ccgaggugcg guacgagguc      600

ugcgacaucc cccagugcuc cgagguggag ugcaugaccu gcaacgggga gagcuaccgc      660

ggccugaugg accacaccga guccggcaag aucugccagc ggugggacca ccagaccccg      720

caccgccaca aguuccuccc cgagcgguac cccgacaagg gguucgacga caacuacugc      780

cgcaaccccg acggccagcc gcggcccugg ugcuacacgc uggaccccca cacccgcugg      840

gaguacugcg ccaucaagac cugcgccgac aacaccauga acgacacgga cgugccccug      900

gagaccaccg agugcaucca ggggcagggc gagggcuacc gggggaccgu caacacgauc      960

uggaacggca ucccgugcca gcgcugggac agccaguacc cccacgagca cgacaugacc     1020

cccgagaacu ucaagugcaa ggaccuccgg gagaacuacu gccgcaaccc cgacgggucc     1080

gagagcccgu ggugcuucac caccgacccc aacauccgcg ugggcuacug cucccagauc     1140

cccaacugcg acaugagcca cgggcaggac ugcuaccggg gcaacggcaa gaacuacaug     1200

gggaaccuga gccagacgcg cuccggccug accugcagca ugugggacaa gaacauggag     1260

gaccuccacc ggcacaucuu cugggagccc gacgcgucca agcugaacga gaacuacugc     1320

cgcaacccgg acgacgacgc ccacgggccc uggugcuaca ccggcaaccc ccugaucccg     1380

ugggacuacu gccccaucag ccggugcgag ggggacacca cgcccaccau cgugaaccuc     1440

gaccaccccg ucaucuccug cgccaagacc aagcagcugc gcguggugaa cggcaucccg     1500

acccggacga acaucggcug gauggucagc cugcgcuacc ggaacaagca caucugcggg     1560

ggcucccuca ucaaggagag cugggugcug accgcccgcc agugcuuccc cucccgggac     1620

cugaaggacu acgaggccug gcucgggauc cacgacgugc acggccgcgg ggacgagaag     1680

ugcaagcagg uccugaacgu gagccagcug guguacggcc ccgagggcuc cgaccucguc     1740

cugaugaagc uggcgcggcc cgccgugcuc gacgacuucg ugagcaccau cgaccugccg     1800

aacuacgggu gcaccauccc cgagaagacg uccugcagcg ucuacggcug gggguacacc     1860

ggccugauca acuacgacgg ccuccugcgc guggcccacc uguacaucau ggggaacgag     1920

aagugcuccc agcaccaccg gggcaagguc acccucaacg agagcgagau cugcgccggg     1980

gccgagaaga ucggcuccgg gcccugcgag ggcgacuacg gcgggccccu ggugugcgag     2040

cagcacaaga ugcgcauggu gcugggcguc aucgugccgg ggcggggcug cgcgaucccc     2100

aaccgccccg ggaucuucgu gcgggucgcc uacuacgcca aguggaucca caagaucauc     2160

cucaccuaca aggugcccca gagcuga                                         2187


<210>  260
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  260
auggccaagg ccgcggccau cggcaucgac cuggggacca ccuacagcug cgugggcgug       60

uuccagcacg ggaaggugga gaucaucgcc aacgaccagg gcaaccgcac gacccccucc      120

uacguggccu ucaccgacac cgagcggcuc aucggggacg ccgcgaagaa ccaggucgcc      180

cugaacccgc agaacacggu guucgacgcc aagcgccuga ucggccggaa guucggcgac      240

cccguggucc agagcgacau gaagcacugg cccuuccagg ugaucaacga cggggacaag      300

cccaaggugc aggucuccua caagggcgag accaaggccu ucuacccgga ggagaucagc      360

uccauggugc ucaccaagau gaaggagauc gcggaggccu accuggggua ccccgugacc      420

aacgccguca ucacggugcc cgccuacuuc aacgacagcc agcgccaggc caccaaggac      480

gcgggcguga ucgccgggcu gaacguccuc cggaucauca acgagcccac cgccgccgcc      540

aucgcguacg gccuggaccg caccggcaag ggggagcgga acgugcugau cuucgaccuc      600

ggcgggggca cguucgacgu guccauccug accaucgacg acggcaucuu cgaggucaag      660

gccaccgccg gggacaccca ccugggcggg gaggacuucg acaaccgccu cgugaaccac      720

uucguggagg aguucaagcg gaagcacaag aaggacauca gccagaacaa gcgcgccguc      780

cggcgccugc ggacggccug cgagcgcgcg aagcggaccc uguccagcuc cacccaggcc      840

agccucgaga ucgacucccu guucgagggc aucgacuucu acaccagcau cacgcgcgcc      900

cgguucgagg agcugugcuc cgaccucuuc cgcagcaccc uggagccggu ggagaaggcc      960

cugcgggacg ccaagcucga caaggcgcag auccacgacc uggugcuggu cgggggcucc     1020

acccgcaucc ccaaggugca gaagcuccug caggacuucu ucaacggccg ggaccugaac     1080

aagagcauca accccgacga ggccgucgcc uacggggccg cggugcaggc cgccauccuc     1140

augggcgaca aguccgagaa cgugcaggac cugcugcucc uggacgucgc gccccugagc     1200

cucgggcugg agaccgccgg cggggugaug acggcccuga ucaagcgcaa cagcaccauc     1260

ccgaccaagc agacccagau cuucacgacc uacuccgaca accagcccgg cgugcucauc     1320

caggucuacg agggcgagcg cgccaugacc aaggacaaca accugcuggg gcgguucgag     1380

cucagcggca ucccgcccgc gccccgcggg gugccccaga ucgaggugac cuucgacauc     1440

gacgccaacg gcauccugaa cgucacggcc accgacaagu ccaccgggaa ggccaacaag     1500

aucaccauca cgaacgacaa gggccggcug agcaaggagg agaucgagcg cauggugcag     1560

gaggccgaga aguacaaggc cgaggacgag gugcagcggg agcgcgucuc cgccaagaac     1620

gcccucgaga gcuacgcguu caacaugaag uccgccgugg aggacgaggg ccugaagggg     1680

aagaucagcg aggccgacaa gaagaaggug cuggacaagu gccaggaggu caucuccugg     1740

cucgacgcca acacccuggc ggagaaggac gaguucgagc acaagcggaa ggagcuggag     1800

caggucugca accccaucau cagcggccuc uaccaggggg ccggcggccc cgggccgggc     1860

ggguucggcg cccaggggcc caagggcggc uccgggagcg gccccaccau cgaggaggug     1920

gacuga                                                                1926


<210>  261
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  261
auggccaagg ccgcggccau cggcaucgac cuggggacca ccuacagcug cgugggcgug       60

uuccagcacg ggaaggugga gaucaucgcc aacgaccagg gcaaccgcac gacccccucc      120

uacguggccu ucaccgacac cgagcggcuc aucggggacg ccgcgaagaa ccaggucgcc      180

cugaacccgc agaacacggu guucgacgcc aagcgccuga ucggccggaa guucggcgac      240

cccguggucc agagcgacau gaagcacugg cccuuccagg ugaucaacga cggggacaag      300

cccaaggugc aggucuccua caagggcgag accaaggccu ucuacccgga ggagaucagc      360

uccauggugc ucaccaagau gaaggagauc gcggaggccu accuggggua ccccgugacc      420

aacgccguca ucacggugcc cgccuacuuc aacgacagcc agcgccaggc caccaaggac      480

gcgggcguga ucgccgggcu gaacguccuc cggaucauca acgagcccac cgccgccgcc      540

aucgcguacg gccuggaccg caccggcaag ggggagcgga acgugcugau cuucgaccuc      600

ggcgggggca cguucgacgu guccauccug accaucgacg acggcaucuu cgaggucaag      660

gccaccgccg gggacaccca ccugggcggg gaggacuucg acaaccgccu cgugaaccac      720

uucguggagg aguucaagcg gaagcacaag aaggacauca gccagaacaa gcgcgccguc      780

cggcgccugc ggacggccug cgagcgcgcg aagcggaccc uguccagcuc cacccaggcc      840

agccucgaga ucgacucccu guucgagggc aucgacuucu acaccagcau cacgcgcgcc      900

cgguucgagg agcugugcuc cgaccucuuc cgcagcaccc uggagccggu ggagaaggcc      960

cugcgggacg ccaagcucga caaggcgcag auccacgacc uggugcuggu cgggggcucc     1020

acccgcaucc ccaaggugca gaagcuccug caggacuucu ucaacggccg ggaccugaac     1080

aagagcauca accccgacga ggccgucgcc uacggggccg cggugcaggc cgccauccuc     1140

augggcgaca aguccgagaa cgugcaggac cugcugcucc uggacgucgc gccccugagc     1200

cucgggcugg agaccgccgg cggggugaug acggcccuga ucaagcgcaa cagcaccauc     1260

ccgaccaagc agacccagau cuucacgacc uacuccgaca accagcccgg cgugcucauc     1320

caggucuacg agggcgagcg cgccaugacc aaggacaaca accugcuggg gcgguucgag     1380

cucagcggca ucccgcccgc gccccgcggg gugccccaga ucgaggugac cuucgacauc     1440

gacgccaacg gcauccugaa cgucacggcc accgacaagu ccaccgggaa ggccaacaag     1500

aucaccauca cgaacgacaa gggccggcug agcaaggagg agaucgagcg cauggugcag     1560

gaggccgaga aguacaaggc cgaggacgag gugcagcggg agcgcgucuc cgccaagaac     1620

gcccucgaga gcuacgcguu caacaugaag uccgccgugg aggacgaggg ccugaagggg     1680

aagaucagcg aggccgacaa gaagaaggug cuggacaagu gccaggaggu caucuccugg     1740

cucgacgcca acacccuggc ggagaaggac gaguucgagc acaagcggaa ggagcuggag     1800

caggucugca accccaucau cagcggccuc uaccaggggg ccggcggccc cgggccgggc     1860

ggguucggcg cccaggggcc caagggcggc uccgggagcg gccccaccau cgaggaggug     1920

gacuga                                                                1926


<210>  262
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  262
auggccaccg ccaagggcau cgcgaucggg aucgaccugg gcaccacgua cagcugcgug       60

ggggucuucc agcacggcaa gguggagauc aucgccaacg accaggggaa ccgcaccacc      120

cccuccuacg uggccuucac cgacacggag cggcucaucg gcgacgccgc caagaaccag      180

gucgcgauga acccgcagaa caccguguuc gacgccaagc gccugaucgg ccggaaguuc      240

aacgaccccg ugguccaggc cgacaugaag cuguggcccu uccaggugau caacgagggc      300

gggaagccca aggugcucgu cagcuacaag ggggagaaca aggccuucua cccggaggag      360

aucuccagca uggugcugac caagcugaag gagaccgcgg aggccuuccu cggccacccc      420

gugacgaacg ccgucaucac cgugcccgcc uacuucaacg acucccagcg ccaggccacc      480

aaggacgcgg gggugaucgc cggccugaac guccugcgga ucaucaacga gcccaccgcc      540

gccgccaucg cguacggccu cgacaagggc gggcaggggg agcgccacgu gcugaucuuc      600

gaccugggcg gcgggacguu cgacgugagc auccucacca ucgacgacgg caucuucgag      660

gucaaggcca ccgccgggga cacccaccug ggcggggagg acuucgacaa ccggcuggug      720

ucccacuucg uggaggaguu caagcgcaag cacaagaagg acaucagcca gaacaagcgg      780

gccguccgcc ggcuccgcac ggccugcgag cgggcgaagc gcacccuguc cagcuccacc      840

caggccaacc uggagaucga cagccucuac gagggcaucg acuucuacac cuccaucacg      900

cgggcccgcu ucgaggagcu gugcgccgac cuguuccggg gcacccucga gccgguggag      960

aaggcccugc gcgacgcgaa gauggacaag gccaagaucc acgacaucgu gcuggucggg     1020

ggcagcaccc ggauccccaa ggugcagcgc cuccugcagg acuacuucaa cgggcgggac     1080

cugaacaagu ccaucaaccc cgacgaggcc gucgccuacg gcgcggccgu gcaggccgcc     1140

auccucaugg gggacaagag cgagaaggug caggaccugc ugcuccugga cgucgcgccc     1200

cugucccucg gccuggagac cgccggcggg gugaugacgg cccugaucaa gcgcaacagc     1260

accaucccga ccaagcagac ccagaucuuc acgaccuacu ccgacaacca gcccggcgug     1320

cucauccagg ucuacgaggg ggagcgcgcc augaccaagg acaacaaccu gcugggccgg     1380

uucgaccuca ccgggauccc gcccgcgccc cgcggcgugc cccagaucga ggugacguuc     1440

gacaucgacg ccaacggcau ccugaacguc accgccaccg acaagagcac cgggaaggug     1500

aacaagauca cgaucaccaa cgacaagggc cggcugagca aggaggagau cgagcgcaug     1560

gugcucgacg ccgagaagua caaggccgag gacgaggucc agcgggagaa gaucgccgcc     1620

aagaacgcgc uggaguccua cgccuucaac augaaguccg uggugagcga cgaggggcug     1680

aagggcaaga ucagcgaguc cgacaagaac aagauccucg acaagugcaa cgagcugcug     1740

agcuggcucg aggucaacca gcuggccgag aaggacgagu ucgaccacaa gcgcaaggag     1800

cuggagcaga ugugcaaccc caucaucacc aagcuguacc agggcgggug caccggcccc     1860

gccugcggga ccggcuacgu gccggggcgg cccgcgacgg gccccaccau cgaggaggug     1920

gacuga                                                                1926


<210>  263
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  263
augagcgccc gcggccccgc caucgggauc gaccugggca ccaccuacuc cugcgugggg       60

gucuuccagc acggcaaggu ggagaucauc gcgaacgacc aggggaaccg gacgaccccg      120

agcuacgugg ccuucaccga caccgagcgc cucaucggcg acgccgccaa gaaccagguc      180

gccaugaacc ccacgaacac caucuucgac gcgaagcggc ugaucggccg caaguucgag      240

gacgccaccg ugcaguccga caugaagcac uggcccuucc ggguggucag cgagggcggg      300

aagcccaagg uccaggugga guacaagggg gagaccaaga cguucuuccc ggaggagauc      360

uccagcaugg ugcugaccaa gaugaaggag aucgccgagg ccuaccucgg cgggaaggug      420

cacuccgcgg ugaucaccgu ccccgccuac uucaacgaca gccagcgcca ggccaccaag      480

gacgccggca cgaucaccgg ccugaacgug cugcggauca ucaacgagcc caccgccgcg      540

gccaucgccu acgggcucga caagaagggc ugcgccgggg gcgagaagaa cgugcugauc      600

uucgaccugg gcgggggcac cuucgacguc uccauccuca cgaucgagga cgggaucuuc      660

gaggucaaga gcaccgccgg cgacacccac cucgggggcg aggacuucga caaccgcaug      720

gugucccacc uggcggagga guucaagcgg aagcacaaga aggacaucgg ccccaacaag      780

cgcgccgugc ggcgccugcg gaccgccugc gagcgcgcca agcggacgcu gagcuccagc      840

acccaggccu ccaucgagau cgacagccug uacgaggggg uggacuucua caccuccauc      900

acccgcgcgc gguucgagga gcucaacgcc gaccuguucc gcggcacgcu ggagccggug      960

gagaaggccc uccgggacgc caagcuggac aaggggcaga uccaggagau cguccuggug     1020

ggcgggagca cccgcauccc caagauccag aagcuccugc aggacuucuu caacggcaag     1080

gagcugaaca aguccaucaa ccccgacgag gccguggcgu acggcgccgc cguccaggcc     1140

gcgauccuca ucggggacaa gagcgagaac gugcaggacc ugcugcuccu ggacgucacg     1200

ccccugagcc ucggcaucga gaccgccggg ggcgugauga ccccgcugau caagcggaac     1260

accaccaucc ccaccaagca gacgcagacc uucaccaccu acuccgacaa ccagagcucc     1320

gugcuggucc agguguacga gggggagcgc gccaugacga aggacaacaa ccuccugggc     1380

aaguucgacc ugaccggcau cccgcccgcg ccccgcgggg ugccccagau cgaggucacc     1440

uucgacaucg acgccaacgg cauccucaac gugaccgccg ccgacaagag caccgggaag     1500

gagaacaaga ucacgaucac caacgacaag ggccggcugu ccaaggacga caucgaccgc     1560

auggugcagg aggccgagcg guacaagagc gaggacgagg ccaaccgcga ccgggucgcc     1620

gcgaagaacg cccuggaguc cuacaccuac aacaucaagc agaccgugga ggacgagaag     1680

cuccgcggca agaucagcga gcaggacaag aacaagaucc uggacaagug ccaggaggug     1740

aucaacuggc uggaccggaa ccagauggcc gagaaggacg aguacgagca caagcagaag     1800

gagcucgagc gcgucugcaa ccccaucauc uccaagcugu accagggcgg gcccgggggc     1860

gggagcggcg gcgggggcuc cggggccagc ggcgggccga cgaucgagga gguggacuga     1920


<210>  264
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  264
augagcgugg ucggcaucga ccugggguuc caguccugcu acguggccgu ggcccgcgcg       60

ggcgggaucg agaccaucgc caacgaguac agcgaccggu gcacccccgc cugcaucucc      120

uucggcccga agaaccgcag caucggggcc gccgcgaagu cccaggucau cagcaacgcc      180

aagaacacgg ugcagggcuu caagcgguuc cacggccgcg ccuucuccga ccccuucgug      240

gaggccgaga aguccaaccu cgcguacgac aucguccagc ugcccaccgg gcugaccggc      300

aucaagguga ccuacaugga ggaggagcgg aacuucacga ccgagcaggu caccgccaug      360

cuccugagca agcugaagga gaccgccgag agcgugcuca agaagcccgu gguggacugc      420

gucguguccg ugccgugcuu cuacacggac gccgagcgcc ggagcgucau ggacgccacc      480

cagaucgcgg ggcugaacug ccugcgccuc augaacgaga ccaccgccgu ggcccuggcc      540

uacggcaucu acaagcagga ccugcccgcc cucgaggaga agccccggaa cguggucuuc      600

guggacaugg ggcacuccgc guaccaggug agcgucugcg ccuucaaccg cggcaagcug      660

aaggugcugg ccacggccuu cgacaccacc cucggcgggc ggaaguucga cgaggugcug      720

gucaaccacu ucugcgagga guucggcaag aaguacaagc uggacaucaa guccaagauc      780

cgcgcccucc ugcggcugag ccaggagugc gagaagcuca agaagcugau guccgcgaac      840

gccagcgacc ugccccucuc caucgagugc uucaugaacg acguggacgu cagcgggacc      900

augaaccgcg gcaaguuccu ggagaugugc aacgaccugc ucgcccgggu ggagccgccc      960

cugcgcagcg ugcuggagca gacgaagcuc aagaaggagg acaucuacgc cgucgagauc     1020

gugggcgggg ccacccggau ccccgcggug aaggagaaga ucuccaaguu cuucggcaag     1080

gagcugagca ccacccugaa cgccgacgag gccgucacgc gcgggugcgc ccuccagugc     1140

gcgauccugu cccccgccuu caaggugcgg gaguucagca ucaccgacgu ggucccguac     1200

cccaucuccc ugcgcuggaa cagccccgcc gaggagggcu ccagcgacug cgagguguuc     1260

uccaagaacc acgccgcccc cuucagcaag gugcucaccu ucuaccggaa ggagccguuc     1320

acccuggagg cguacuacuc cagcccccag gaccugcccu accccgaccc ggccaucgcc     1380

caguucuccg uccagaaggu gacgccccag agcgacgggu ccagcuccaa ggugaagguc     1440

aaggugcgcg ugaacgucca cggcaucuuc agcgugucca gcgccagccu cguggagguc     1500

cacaaguccg aggagaacga ggagcccaug gagaccgacc agaacgccaa ggaggaggag     1560

aagaugcagg ucgaccagga ggagccccac guggaggagc agcagcagca gaccccggcg     1620

gagaacaagg ccgagagcga ggagauggag accucccagg ccggcagcaa ggacaagaag     1680

auggaccagc cgccccaggc caagaaggcc aaggugaaga cguccaccgu ggaccugccc     1740

aucgagaacc agcugcucug gcagaucgac cgcgagaugc ugaaccugua caucgagaac     1800

gaggggaaga ugaucaugca ggacaagcuc gagaaggagc ggaacgacgc gaagaacgcc     1860

guggaggagu acgucuacga gaugcgcgac aagcugagcg gcgaguacga gaaguucgug     1920

uccgaggacg accggaacag cuucacccug aagcucgagg acaccgagaa cuggcuguac     1980

gaggacgggg aggaccagcc caagcagguc uacguggaca agcuggccga gcugaagaac     2040

cucggccagc ccaucaagau ccgcuuccag gaguccgagg agcggcccaa gcuguucgag     2100

gagcugggga agcagaucca gcaguacaug aagaucauca gcuccuucaa gaacaaggag     2160

gaccaguacg accaccucga cgccgcggac augacgaagg uggagaaguc caccaacgag     2220

gccauggagu ggaugaacaa caagcugaac cugcagaaca agcagagccu caccauggac     2280

ccggugguca agagcaagga gaucgaggcc aagaucaagg agcugaccuc cacgugcagc     2340

cccaucaucu ccaagcccaa gcccaaggug gagccgccca aggaggagca gaagaacgcc     2400

gagcagaacg gccccgugga cggccagggg gacaaccccg gcccgcaggc cgcggagcag     2460

gggaccgaca ccgccguccc cagcgacagc gacaagaagc ugcccgagau ggacaucgac     2520

uga                                                                   2523


<210>  265
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  265
augagcgugg ucggcaucga ccugggguuc cucaacugcu acaucgccgu ggcccgcucc       60

ggcgggaucg agaccaucgc gaacgaguac agcgaccggu gcacccccgc cugcaucucc      120

cugggcagcc gcacgcgggc caucgggaac gccgccaagu cccagaucgu gaccaacguc      180

cgcaacacca uccacggcuu caagaagcug cacggccgga gcuucgacga cccgaucgug      240

cagaccgagc gcauccggcu ccccuacgag cugcagaaga ugcccaacgg guccgcgggc      300

gugaaggucc gcuaccugga ggaggagcgg cccuucgcca ucgagcaggu cacggggaug      360

cuccuggcca agcugaagga gaccagcgag aacgcccuca agaagccggu ggcggacugc      420

gugaucucca uccccagcuu cuucaccgac gccgagcgcc gguccgugau ggccgccgcc      480

cagguggcgg gccugaacug ccugcgccuc augaacgaga ccacggccgu cgcccuggcc      540

uacgggaucu acaagcagga ccugccgccc cucgacgaga agccccggaa cgugguguuc      600

aucgacaugg gccacagcgc cuaccagguc cuggugugcg cguucaacaa gggcaagcug      660

aaggugcucg ccaccaccuu cgaccccuac cucgggggcc gcaacuucga cgaggcccug      720

gucgacuacu ucugcgacga guucaagacc aaguacaaga ucaacgugaa ggagaacucc      780

cgggcccugc ugcgccugua ccaggagugc gagaagcuca agaagcugau gagcgccaac      840

gcguccgacc ugccccucaa caucgagugc uucaugaacg accuggacgu gagcuccaag      900

augaaccggg cccaguucga gcagcugugc gccagccucc uggcccgcgu cgagcccccg      960

cugaaggccg ugauggagca ggcgaaccuc cagcgggagg acaucuccag caucgagauc     1020

gucgggggcg ccacgcgcau ccccgccgug aaggagcaga ucaccaaguu cuuccugaag     1080

gacaucagca ccacccugaa cgccgacgag gcgguggccc ggggcugcgc ccuccagugc     1140

gccauccugu cccccgccuu caagguccgc gaguucagca ucacggaccu ggugcccuac     1200

uccaucaccc uccgcuggaa gaccagcuuc gaggacgggu ccggcgagug cgagguguuc     1260

ugcaagaacc acccggcgcc cuucagcaag gucaucaccu uccacaagaa ggagcccuuc     1320

gagcuggagg ccuucuacac gaaccugcac gaggugcccu acccggacgc ccggaucggg     1380

uccuucacca uccagaacgu guucccccag agcgacggcg acuccagcaa ggucaaggug     1440

aaggugcgcg ucaacaucca cgggaucuuc uccguggcca gcgccuccgu gaucgagaag     1500

cagaaccucg agggcgacca cagcgacgcg cccauggaga ccgagaccuc cuucaagaac     1560

gagaacaagg acaacaugga caagaugcag gucgaccagg aggagggcca ccagaagugc     1620

cacgccgagc acacgcccga ggaggagauc gaccacaccg gggccaagac caagagcgcc     1680

guguccgaca agcaggaccg gcugaaccag acccugaaga agggcaaggu caagagcauc     1740

gaccucccga uccaguccag ccugugccgc cagcuggggc aggaccuccu gaacagcuac     1800

aucgagaacg agggcaagau gaucaugcag gacaagcugg agaaggagcg gaacgacgcc     1860

aagaacgcgg uggaggagua cguguacgac uuccgcgacc ggcuggggac gguguacgag     1920

aaguucauca cccccgagga ccucuccaag cugagcgccg uccuggagga caccgagaac     1980

uggcucuacg aggacggcga ggaccagccc aagcaggucu acguggacaa gcugcaggag     2040

cugaagaagu acggccagcc cauccagaug aaguacaugg agcacgagga gcgcccgaag     2100

gcccucaacg accuggggaa gaagauccag cuggugauga aggugaucga ggccuaccgg     2160

aacaaggacg agcgcuacga ccaccucgac cccaccgaga uggagaaggu ggagaagugc     2220

aucuccgacg cgaugagcug gcugaacucc aagaugaacg cccagaacaa gcugagccuc     2280

acgcaggacc ccgucgugaa gguguccgag aucgucgcca agagcaagga gcuggacaac     2340

uucugcaacc cgaucaucua caagcccaag cccaaggccg aggugcccga ggacaagccg     2400

aaggccaacu ccgagcacaa cggccccaug gacgggcaga gcggcaccga gaccaagucc     2460

gacagcacca aggacuccag ccagcacacg aaguccagcg gggagaugga gguggacuga     2520


<210>  266
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  266
augaagcuga gccucguggc cgccaugcug cugcuccugu ccgcggcccg cgccgaggag       60

gaggacaaga aggaggacgu cggcaccgug guggggaucg accugggcac cacguacagc      120

ugcgucgggg uguucaagaa cggccgggug gagaucaucg ccaacgacca ggggaaccgc      180

aucacccccu ccuacgucgc cuucaccccg gagggcgagc ggcucaucgg cgacgcggcc      240

aagaaccagc ugaccagcaa ccccgagaac acgguguucg acgccaagcg ccugaucggg      300

cggaccugga acgaccccuc cgugcagcag gacaucaagu uccuccccuu caaggucgug      360

gagaagaaga ccaagccgua cauccaggug gacaucggcg ggggccagac caagacguuc      420

gcccccgagg agaucagcgc gaugguccug accaagauga aggagaccgc cgaggccuac      480

cuggggaaga aggugaccca cgccgugguc acggugcccg ccuacuucaa cgacgcgcag      540

cgccaggcca ccaaggacgc cggcaccauc gccggccuca acgugaugcg gaucaucaac      600

gagcccaccg ccgcggccau cgccuacggg cuggacaagc gcgagggcga gaagaacauc      660

cuggucuucg accucggggg cggcacguuc gacguguccc ugcugaccau cgacaacggg      720

guguucgagg ucguggccac caacggcgac acccaccucg ggggcgagga cuucgaccag      780

cgggugaugg agcacuucau caagcuguac aagaagaaga cggggaagga cguccgcaag      840

gacaaccggg ccgugcagaa gcugcgccgg gaggucgaga aggcgaagcg cgcccucagc      900

ucccagcacc aggcccggau cgagaucgag agcuucuacg agggcgagga cuucuccgag      960

acccugaccc gcgccaaguu cgaggagcug aacauggacc ucuuccggag caccaugaag     1020

ccggugcaga aggugcugga ggacuccgac cugaagaagu ccgacaucga cgagaucguc     1080

cucgugggcg ggagcacgcg cauccccaag auccagcagc uggugaagga guucuucaac     1140

ggcaaggagc ccagccgggg gaucaacccc gacgaggccg ucgcguacgg cgccgccgug     1200

caggccgggg ugcuguccgg cgaccaggac accggcgacc ucguccugcu ggacgugugc     1260

ccgcucaccc uggggaucga gaccgugggc ggggucauga cgaagcugau cccccgcaac     1320

accguggugc ccaccaagaa gucccagauc uucagcaccg cgagcgacaa ccagcccacg     1380

gucaccauca agguguacga gggcgagcgg ccgcucacca aggacaacca ccuccugggg     1440

accuucgacc ugacgggcau cccgcccgcg ccccgcggcg ugccccagau cgaggucacc     1500

uucgagaucg acgugaacgg gauccugcgc gugaccgccg aggacaaggg caccgggaac     1560

aagaacaaga ucaccaucac gaacgaccag aaccggcuga cccccgagga gaucgagcgc     1620

auggucaacg acgccgagaa guucgccgag gaggacaaga agcucaagga gcggaucgac     1680

acccgcaacg agcuggagag cuacgccuac ucccugaaga accagaucgg cgacaaggag     1740

aagcucggcg ggaagcugag cuccgaggac aaggagacca uggagaaggc cguggaggag     1800

aagaucgagu ggcuggagag ccaccaggac gccgacaucg aggacuucaa ggccaagaag     1860

aaggagcucg aggagaucgu gcagcccauc aucuccaagc uguacggcag cgccgggccc     1920

ccgcccacgg gcgaggagga caccgcggag aaggacgagc uguga                     1965


<210>  267
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  267
augcaggcgc cccgcgagcu ggccgugggc aucgaccucg ggaccaccua cagcugcguc       60

ggcguguucc agcaggggcg gguggagauc cuggccaacg accagggcaa ccgcacgacc      120

ccguccuacg ucgccuucac cgacaccgag cggcuggugg gggacgccgc caagagccag      180

gccgcgcuca acccccacaa cacgguguuc gacgccaagc gccugaucgg ccggaaguuc      240

gccgacacca ccguccaguc cgacaugaag cacuggcccu uccgcguggu gagcgagggc      300

gggaagccca agguccgggu gugcuaccgc ggcgaggaca agaccuucua cccggaggag      360

aucuccagca uggugcuguc caagaugaag gagacggccg aggcguaccu cgggcagccc      420

gucaagcacg ccgugaucac cgugcccgcc uacuucaacg acagccagcg gcaggccacc      480

aaggacgccg gcgcgaucgc cgggcugaac guccugcgca ucaucaacga gcccaccgcc      540

gccgccaucg cguacggccu cgaccggcgc ggcgccgggg agcggaacgu gcugaucuuc      600

gaccugggcg ggggcacguu cgacgugucc guccucagca ucgacgccgg cguguucgag      660

gugaaggcca ccgccgggga cacccaccug ggcggggagg acuucgacaa ccgccugguc      720

aaccacuuca uggaggaguu ccggcgcaag cacggcaagg accucuccgg gaacaagcgg      780

gcgcugcgcc ggcugcgcac cgccugcgag cgggccaagc gcacgcucag cuccagcacc      840

caggccaccc uggagaucga cucccuguuc gagggcgugg acuucuacac cagcaucacg      900

cgcgcccggu ucgaggagcu cugcuccgac cuguuccgca gcacccugga gccgguggag      960

aaggcgcucc gggacgccaa gcuggacaag gcccagaucc acgacgucgu gcuggucggc     1020

ggguccaccc gcauccccaa ggugcagaag cuccugcagg acuucuucaa cggcaaggag     1080

cugaacaaga gcaucaaccc cgacgaggcc guggcguacg gggccgccgu ccaggccgcc     1140

gugcucaugg gcgacaagug cgagaaggug caggaccugc ugcuccugga cgucgcgccc     1200

cugagccucg ggcuggagac cgccggcggc gugaugacga cccugaucca gcggaacgcc     1260

accaucccga ccaagcagac gcagaccuuc accaccuacu ccgacaacca gcccggggug     1320

uucauccagg ucuacgaggg cgagcgcgcc augacgaagg acaacaaccu ccuggggcgg     1380

uucgagcuga gcggcauccc gcccgcgccc cgcggggugc cccagaucga ggugaccuuc     1440

gacaucgacg ccaacggcau ccucuccguc accgccaccg accggagcac gggcaaggcc     1500

aacaagauca ccaucaccaa cgacaagggg cgccugucca aggaggaggu ggagcggaug     1560

gugcacgagg ccgagcagua caaggccgag gacgaggcgc agcgcgaccg ggucgccgcc     1620

aagaacagcc uggaggccca cguguuccac gugaagggcu cccuccagga ggagagccug     1680

cgcgacaaga uccccgagga ggaccggcgc aagaugcagg acaagugccg ggagguccug     1740

gcguggcucg agcacaacca gcuggccgag aaggaggagu acgagcacca gaagcgcgag     1800

cuggagcaga ucugccggcc caucuucucc cgccuguacg ggggcccggg cgugcccggg     1860

ggcagcuccu gcgggaccca ggcccgccag ggcgacccca gcaccgggcc caucaucgag     1920

gagguggacu ga                                                         1932


<210>  268
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__P48741__HsHSPA7

<400>  268
augcaggcgc cccgcgagcu ggccgugggc aucgaccucg ggaccaccua cagcugcguc       60

ggcguguucc agcaggggcg gguggagauc cuggccaacg accagggcaa ccgcacgacc      120

ccguccuacg ucgccuucac cgacaccgag cggcuggugg gggacgccgc caagagccag      180

gccgcgcuca acccccacaa cacgguguuc gacgccaagc gccugaucgg ccggaaguuc      240

gccgacacca ccguccaguc cgacaugaag cacuggcccu uccagguggu gagcgagggc      300

gggaagccca agguccgcgu gugcuaccgg ggcgaggaca agaccuucua cccggaggag      360

aucuccagca uggugcuguc caagaugaag gagacggccg aggcguaccu cgggcagccc      420

gucaagcacg ccgugaucac cgugcccacc uacuucagca acucccagcg ccaggccacc      480

aaggacgccg gcgccaucgc ggggcugaag guccugccca ucaucaacga ggccacggcc      540

gccgccaucg cguacggccu cgaccggcgc ggcgccggga agcggaacgu gcugaucuuc      600

gaccugggcg ggggcaccuu cgacgugagc guccucucca ucgacgccgg cguguucgag      660

gugaaggcca ccgccgggga cacccaccug ggcggggagg acuucgacaa ccgccugguc      720

aaccacuuca uggaggaguu ccggcgcaag cacggcaagg accucagcgg gaacaagcgg      780

gcgcugcgcc ggcugcgcac ggccugcgag cgggccaagc gcaccccguc cagcuccacc      840

caggccaccc ucgagaucga cagccuguuc gagggcgugg acuucuacaa guccaucacg      900

cgggcccgcu ucgaggagcu gugcagcgac cucuuccgcu ccacccugga gcccguggag      960

aaggcgcugc gggacgccaa gcucgacaag gcccagaucc acgacuucgu ccugggcggg     1020

ggccugcaca gccaccccca gggggccgag guggcggccg gccuccugca gcgccagggg     1080

gccgagcagg agcaccagcc cuga                                            1104


<210>  269
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  269
augagcaagg gccccgccgu ggggaucgac cugggcacca ccuacuccug cgucggggug       60

uuccagcacg gcaaggugga gaucaucgcc aacgaccagg ggaaccgcac gacccccagc      120

uacgucgcgu ucaccgacac cgagcggcuc aucggcgacg ccgccaagaa ccagguggcc      180

augaacccca cgaacaccgu guucgacgcc aagcgccuga ucggccggcg cuucgacgac      240

gcggucgugc aguccgacau gaagcacugg cccuucaugg uggucaacga cgccgggcgg      300

cccaaggucc agguggagua caagggcgag accaagagcu ucuacccgga ggaggugucc      360

agcauggugc ugaccaagau gaaggagauc gccgaggccu accucgggaa gacggugacc      420

aacgcggucg ugaccgugcc cgccuacuuc aacgacuccc agcgccaggc caccaaggac      480

gccggcacga ucgccgggcu gaacguccug cggaucauca acgagcccac cgcggccgcc      540

aucgccuacg gccucgacaa gaaggugggc gccgagcgca acgugcugau cuucgaccuc      600

gggggcggga ccuucgacgu cagcauccug accaucgagg acggcaucuu cgaggugaag      660

uccacggcgg gcgacaccca ccucgggggc gaggacuucg acaaccggau ggugaaccac      720

uucaucgccg aguucaagcg caagcacaag aaggacauca gcgagaacaa gcgggccguc      780

cgccggcugc gcaccgccug cgagcgggcc aagcgcaccc uguccagcuc cacgcaggcg      840

agcaucgaga ucgacucccu guacgagggg aucgacuucu acaccagcau cacccgggcc      900

cgcuucgagg agcugaacgc cgaccucuuc cggggcaccc uggaccccgu ggagaaggcc      960

cugcgcgacg ccaagcucga caagucccag auccacgaca ucguccuggu cgggggcagc     1020

acgcggaucc cgaagaucca gaagcugcuc caggacuucu ucaacggcaa ggagcugaac     1080

aaguccauca accccgacga ggcgguggcc uacggggccg ccgugcaggc ggccauccug     1140

agcggcgaca agagcgagaa cgugcaggac cuccugcugc ucgacgugac gccccugucc     1200

cuggggaucg agaccgccgg cggggucaug accgugcuca ucaagcgcaa caccaccauc     1260

cccaccaagc agacccagac guucaccacc uacagcgaca accagccggg cgugcugauc     1320

caggucuacg agggcgagcg cgccaugacc aaggacaaca accugcucgg gaaguucgag     1380

cugacgggca ucccgcccgc gccccgcggg gugccccaga ucgaggugac cuucgacauc     1440

gacgccaacg gcauccugaa cgucuccgcc guggacaaga gcaccgggaa ggagaacaag     1500

aucaccauca ccaacgacaa gggccggcuc uccaaggagg acaucgagcg gauggugcag     1560

gaggccgaga aguacaaggc cgaggacgag aagcagcgcg acaaggucag cuccaagaac     1620

agccuggagu ccuacgccuu caacaugaag gcgacggugg aggacgagaa gcugcagggc     1680

aagaucaacg acgaggacaa gcagaagauc cucgacaagu gcaacgagau caucaacugg     1740

cuggacaaga accagaccgc cgagaaggag gaguucgagc accagcagaa ggagcuggag     1800

aaggugugca accccaucau caccaagcuc uaccagagcg ccgggggcau gcccgggggc     1860

augcccggcg gguucccggg cgggggcgcc ccgcccuccg ggggcgccag cuccggcccc     1920

accaucgagg aggucgacug a                                               1941


<210>  270
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  270
augaucagcg ccucccgcgc cgcggccgcc cggcuggugg gcgccgccgc gagccgcggg       60

cccaccgccg cccggcacca ggacuccugg aacggccuca gccacgaggc cuuccgccug      120

gucucccggc gcgacuacgc gagcgaggcc aucaaggggg ccgugguggg caucgaccug      180

gggaccacga acuccugcgu cgccgugaug gagggcaagc aggccaaggu gcucgagaac      240

gcggagggcg cccggaccac cccgagcguc guggccuuca ccgccgacgg ggagcgccug      300

gugggcaugc ccgccaagcg gcaggcgguc acgaacccca acaacaccuu cuacgccacc      360

aagcgccuga ucgggcggcg cuacgacgac cccgaggugc agaaggacau caagaacgug      420

ccguucaaga ucguccgggc cuccaacggc gacgccuggg uggaggccca cgggaagcuc      480

uacagccccu cccagaucgg cgcguucgug cugaugaaga ugaaggagac cgccgagaac      540

uaccugggcc acacggccaa gaacgccguc aucaccgugc ccgccuacuu caacgacagc      600

cagcgccagg cgaccaagga cgccgggcag aucuccggcc ucaacgugcu gcgggucauc      660

aacgagccca ccgccgccgc gcuggccuac gggcucgaca agagcgagga caaggugauc      720

gccguguacg accugggcgg cgggacguuc gacaucucca uccuggagau ccagaagggc      780

gucuucgagg ucaagagcac caacggggac accuuccucg gcggggagga cuucgaccag      840

gcccugcugc gccacaucgu gaaggaguuc aagcgggaga ccggcgugga ccucacgaag      900

gacaacaugg cccugcagcg cgugcgggag gcggccgaga aggccaagug cgagcugucc      960

agcuccgucc agaccgacau caaccucccg uaccugacca uggacagcag cggccccaag     1020

caccugaaca ugaagcucac ccgcgcccag uucgagggga ucgugacgga ccugauccgg     1080

cgcaccaucg cccccugcca gaaggcgaug caggacgccg agguguccaa gagcgacauc     1140

ggcgagguca uccuggucgg gggcaugacc cgcaugccca aggugcagca gaccgugcag     1200

gaccucuucg ggcgggcccc guccaaggcc gugaaccccg acgaggccgu ggcgaucggc     1260

gccgccaucc agggcggggu ccuggccggc gacgugacgg acgugcugcu ccuggacguc     1320

acgccccuga gccucgggau cgagacccug ggcggggugu ucaccaagcu gaucaaccgc     1380

aacaccacca uccccaccaa gaagucccag guguucagca ccgcggccga cggccagacg     1440

caggucgaga ucaaggugug ccagggcgag cgggagaugg ccggggacaa caagcuccug     1500

ggccaguuca cccugaucgg gaucccgccc gcgccccgcg gcgugcccca gaucgagguc     1560

accuucgaca ucgacgccaa cggcaucgug cacguguccg ccaaggacaa ggggaccggc     1620

cgggagcagc agaucgucau ccagagcucc gggggccuca gcaaggacga caucgagaac     1680

auggugaaga acgccgagaa guacgccgag gaggaccgcc ggaagaagga gcgcguggag     1740

gccgucaaca uggccgaggg gaucauccac gacacggaga ccaagaugga ggaguucaag     1800

gaccagcugc cggcggacga gugcaacaag cugaaggagg agaucuccaa gaugcgggag     1860

cuccuggccc gcaaggacag cgagaccggc gagaacaucc ggcaggccgc cuccagccug     1920

cagcaggccu cccucaagcu guucgagaug gcguacaaga agauggccag cgagcgcgag     1980

ggcuccggga gcuccggcac cggggagcag aaggaggacc agaaggagga gaagcaguga     2040


<210>  271
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  271
auggccgaca aggaggccgg cgggagcgac ggcccccgcg agaccgcgcc gaccuccgcc       60

uacagcuccc ccgcccggag ccugggggac acgggcauca cgccccucuc ccccagccac      120

aucgugaacg acaccgacuc caacgucagc gagcagcagu ccuuccuggu gguggucgcc      180

guggacuucg ggaccaccag cuccggcuac gccuacagcu ucaccaagga gccggagugc      240

auccacguga ugcgccggug ggagggcggg gaccccggcg ucuccaacca gaagaccccc      300

accacgaucc ugcucacccc cgagcgcaag uuccacagcu ucggguacgc ggcccgggac      360

uucuaccacg accuggaccc gaacgaggcc aagcaguggc uguaccucga gaaguucaag      420

augaagcugc acaccaccgg cgaccugacg auggacaccg accucaccgc cgcgaacggg      480

aagaagguga aggcccugga gaucuucgcc uacgcccugc aguacuucaa ggagcaggcc      540

cucaaggagc uguccgacca ggcgggcagc gaguucgaga acuccgacgu gcgcuggguc      600

aucaccgugc ccgccaucug gaagcagccc gccaagcagu ucaugcggca ggccgccuac      660

caggcgggcc uggccagccc cgagaacucc gagcagcuca ucaucgcccu ggagccggag      720

gccgccagca ucuacugccg caagcugcgg cuccaccaga ugaucgagcu gagcuccaag      780

gcggccguga acggguacag cggcuccgac acggucgggg ccggcuucac ccaggccaag      840

gagcacaucc gccggaaccg ccagagccgg accuuccugg uggagaacgu gaucggcgag      900

aucugguccg agcucgagga gggggacaag uacgucgugg uggacagcgg cgggggcacc      960

gucgaccuga cggugcacca gauccgccug cccgaggggc accucaagga gcuguacaag     1020

gccaccggcg gccccuacgg gucccugggc guggacuacg aguucgagaa gcuccuguac     1080

aagaucuucg gggaggacuu caucgagcag uucaagauca agcggcccgc ggccuggguc     1140

gaccugauga ucgccuucga gagccgcaag cgggccgcgg ccccggaccg caccaacccc     1200

cucaacauca cccugcccuu cuccuucauc gacuacuaca agaaguuccg gggccacagc     1260

guggagcacg cccugcgcaa guccaacgug gacuucguca aguggagcuc ccaggggaug     1320

cuccggauga gccccgacgc caugaacgcc cuguucaagc cgacgaucga cuccaucauc     1380

gagcaccucc gcgaccuguu ccagaagccc gaggugagca ccgucaaguu ccuguuccug     1440

gugggcggcu ucgcggaggc gccccuccug cagcaggccg ugcaggccgc cuucggggac     1500

cagugccgca ucaucauccc ccaggacguc ggccugacca uccucaaggg ggccgugcug     1560

uucggccugg acccggccgu gaucaagguc cggcgcagcc cccucaccua cggggugggc     1620

gugcugaacc gguacgucga gggcaagcac ccgcccgaga agcugcucgu gaaggacggg     1680

acgcgcuggu gcaccgacgu guucgacaag uucaucuccg ccgaccaguc cgucgcccug     1740

ggcgagcugg ugaagcggag cuacaccccc gccaagccca gccagcuggu gaucgucauc     1800

aacaucuacu ccagcgagca cgacaacgug uccuucauca ccgaccccgg ggugaagaag     1860

ugcggcacgc uccgccugga ccugaccggc accagcggga ccgcgguccc ggcccggcgc     1920

gagauccaga cgcucaugca guucggcgac accgagauca aggccaccgc caucgacauc     1980

gcgaccucca agagcgugaa gguggggauc gacuuccuga acuacuga                  2028


<210>  272
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  272
augcuggccg ugcccgagau gggccuccag gggcuguaca ucggcagcuc ccccgagcgc       60

agccccgucc ccuccccgcc cgggagcccc cggacccagg aguccugcgg caucgccccg      120

cugaccccca gccagucccc caagcccgag gugcgcgcgc cccagcaggc cagcuucucc      180

guggucgugg ccaucgacuu cgggacgacc agcuccggcu acgccuucag cuucgccucc      240

gaccccgagg cgauccacau gaugcggaag ugggagggcg gggacccggg cguggcccac      300

cagaagaccc cgaccugccu ccugcugacg cccgaggggg ccuuccacag cuucggcuac      360

accgcccgcg acuacuacca cgaccucgac cccgaggagg cgcgggacug gcuguacuuc      420

gagaaguuca agaugaagau ccacuccgcc accgaccuga cccucaagac gcagcuggag      480

gccgucaacg ggaagaccau gcccgcccug gagguguucg cccacgcgcu ccgcuucuuc      540

cgggagcacg cccugcagga gcugcgcgag cagagccccu cccuccccga gaaggacacc      600

gugcgguggg uccugaccgu gcccgccauc uggaagcagc cggccaagca guucaugcgc      660

gaggccgcgu accuggccgg ccucgugagc cgggagaacg ccgagcagcu gcugaucgcc      720

cucgagcccg aggccgcguc cgucuacugc cgcaagcugc ggcugcacca gcuccuggac      780

cugagcggcc gcgcccccgg gggcgggcgg cucggcgagc gccggagcau cgacuccagc      840

uuccgccagg cccgggagca gcugcgccgg ucccgccaca gccgcacguu ccugguggag      900

uccggcgugg gggagcucug ggccgagaug caggccggcg accgguacgu cguggcggac      960

ugcgggggcg ggaccgugga ccugaccguc caccagcugg agcagcccca cggcacccuc     1020

aaggagcugu acaaggccag cggcgggccg uacggcgccg ugggggugga ccuggccuuc     1080

gagcagcucc ugugccgcau cuucggcgag gacuucaucg cgacguucaa gcggcagcgc     1140

cccgccgccu gggucgaccu gaccaucgcc uucgaggccc ggaagcgcac cgcggggccc     1200

caccgggccg gcgcccucaa caucucccug cccuucagcu ucaucgacuu cuaccgcaag     1260

cagcggggcc acaacgugga gaccgcccug cgccggucca gcgugaacuu cgucaagugg     1320

uccagccagg ggaugcuccg cauguccugc gaggccauga acgagcuguu ccagccgacg     1380

gugagcggca ucauccagca caucgaggcg cugcucgccc ggcccgaggu ccagggggug     1440

aagcugcugu uccucguggg cggguucgcc gaguccgccg uccugcagca cgccgugcag     1500

gcggcccugg gcgcccgcgg ccugcgggug gucgugcccc acgacguggg gcucaccauc     1560

cugaagggcg ccguccuguu cgggcaggcg ccgggcgugg ugcgcguccg gcgcagcccc     1620

cucaccuacg gcgugggggu gcugaaccgg uucguccccg gccgccaccc gcccgagaag     1680

cugcucgugc gcgacgggcg gcgcuggugc accgacgugu ucgagcgguu cgucgccgcc     1740

gagcaguccg uggcccuggg cgaggaggug cgccggagcu acugccccgc ccgccccggg     1800

cagcggcgcg uccugaucaa ccucuacugc ugcgcggccg aggacgcccg guucaucacg     1860

gaccccggcg ugcgcaagug cggcgcccug ucccuggagc ucgagccggc cgacugcggg     1920

caggacaccg cgggcgcccc gcccgggcgg cgcgagaucc gggccgccau gcaguucggc     1980

gacaccgaga ucaaggugac cgccgucgac gugagcacga accgcagcgu gcgggcgucc     2040

aucgacuucc ugagcaacug a                                               2061


<210>  273
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  273
auggcccggg agaugaccau ccugggcagc gccgugcuca cccugcugcu cgcgggguac       60

cuggcccagc aguaccugcc ccucccgacg cccaagguca ucggcaucga ccuggggacc      120

accuacugcu ccgugggcgu guucuucccc gggaccggca aggucaaggu gauccccgac      180

gagaacggcc acaucagcau cccguccaug gugagcuuca cggacaacga cgucuacgug      240

ggguacgagu ccguggagcu ggccgacagc aacccccaga acaccaucua cgacgccaag      300

cgguucaucg gcaagaucuu caccgccgag gagcucgagg cggagaucgg gcgcuacccc      360

uucaaggucc ugaacaagaa cggcauggug gaguucuccg ugaccagcaa cgagacgauc      420

accgucuccc ccgaguacgu ggggagccgg cugcuccuga agcugaagga gauggccgag      480

gccuaccucg gcaugccggu ggccaacgcg gucaucuccg ugcccgccga guucgaccug      540

aagcagcgca acagcaccau cgaggccgcc aaccuggccg gccucaagau ccugcgggug      600

aucaacgagc ccaccgcggc cgccauggcc uacgggcugc acaaggccga cgucuuccac      660

gugcucguga ucgaccuggg cgggggcacg cuggacgucu cccuccugaa caagcagggc      720

gggauguucc ugacccgcgc gaugagcggc aacaacaagc ucgggggcca ggacuucaac      780

cagcggcugc ugcaguaccu cuacaagcag aucuaccaga ccuacggguu cgugcccucc      840

cgcaaggagg agauccaccg gcugcgccag gccguggaga uggucaagcu gaaccucacc      900

cugcaccaga gcgcccagcu guccgugcuc cugacggucg aggagcagga ccggaaggag      960

ccgcacagcu ccgacaccga gcugcccaag gacaagcuca gcagcgccga cgaccaccgc     1020

gugaacuccg gcuucggccg ggggcugagc gacaagaagu ccggcgagag ccaggugcug     1080

uucgagaccg agaucucccg caagcuguuc gacacccuga acgaggaccu guuccagaag     1140

auccucgucc ccauccagca gguccugaag gaggggcacc uggagaagac ggagaucgac     1200

gagguggugc ucgugggcgg gagcacccgg aucccccgca uccgccaggu gauccaggag     1260

uucuucggca aggacccgaa caccuccguc gaccccgacc uggccguggu gaccggcguc     1320

gcgauccagg ccgggaucga cggcgggagc uggccccucc agguguccgc ccuggagauc     1380

cccaacaagc accuccagaa gacgaacuuc aacuga                               1416


<210>  274
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  274
auggccgcca ucggcgugca ccuggggugc accagcgcgu gcgucgccgu guacaaggac       60

ggccgcgccg ggguggucgc caacgacgcc ggcgaccggg ugacccccgc gguggucgcc      120

uacuccgaga acgaggagau cguggggcuc gccgccaagc agagccgcau ccggaacauc      180

uccaacacgg ugaugaaggu caagcagauc cugggccgca gcuccagcga cccgcaggcg      240

cagaaguaca ucgccgaguc caagugccug gugaucgaga agaacggcaa gcuccgguac      300

gagaucgaca ccggggagga gaccaaguuc gugaaccccg aggacgucgc ccgccugauc      360

uucagcaaga ugaaggagac cgcccacucc gugcugggca gcgacgccaa cgacgugguc      420

aucacggugc ccuucgacuu cggggagaag cagaagaacg cgcucggcga ggccgcccgg      480

gccgccgggu ucaacgugcu gcgccugauc cacgagcccu ccgcggcccu ccuggccuac      540

ggcaucggcc aggacagccc gaccgggaag uccaacaucc uggucuucaa gcucggcggg      600

accagccugu cccugagcgu gauggaggug aacuccggca ucuaccgggu ccucagcacc      660

aacacggacg acaacaucgg cggggcccac uucaccgaga cccuggccca guaccuggcg      720

uccgaguucc agcgcagcuu caagcacgac gugcggggca acgcccgcgc caugaugaag      780

cucaccaaca gcgccgaggu ggccaagcac ucccugagca cgcugggguc cgcgaacugc      840

uuccucgaca gccuguacga gggccaggac uucgacugca acgucucccg ggcccgcuuc      900

gagcugcucu gcagcccccu guucaacaag ugcaucgagg ccauccgggg gcugcucgac      960

cagaacggcu ucaccgccga cgacaucaac aagguggucc ugugcggcgg guccagccgc     1020

auccccaagc ugcagcagcu caucaaggac cuguuccccg cgguggagcu gcucaacucc     1080

aucccgcccg acgaggugau ccccaucggc gccgccaucg aggccgggau ccugaucggc     1140

aaggagaacc ugcucgucga ggacagccug augaucgagu gcuccgcccg ggacauccug     1200

gugaaggggg uggacgagag cggcgcgucc cgcuucaccg uccucuuccc cagcggcacc     1260

ccgcugcccg cccggcgcca gcacacgcug caggcccccg gguccaucag cuccgugugc     1320

cucgagcugu acgagagcga cggcaagaac uccgccaagg aggagaccaa guucgcccag     1380

gugguccugc aggaccucga caagaaggag aacgggcugc gggacauccu ggcggugcuc     1440

accaugaagc gcgacggcag ccugcacgug accugcacgg accaggagac cgggaagugc     1500

gaggccauca gcaucgagau cgccuccuga                                      1530


<210>  275
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  275
augagcgugg ucggccugga cguggggucc cagagcugcu acaucgccgu ggcccgcgcg       60

ggcgggaucg agaccaucgc caacgaguuc uccgaccggu gcacccccag cgucaucucc      120

uucggcagca agaaccgcac caucggggug gccgccaaga accagcagau cacccacgcc      180

aacaacaccg uguccaacuu caagcgguuc cacggccgcg cguucaacga cccguucauc      240

cagaaggaga aggagaaccu cagcuacgac cugguccccc ugaagaacgg cggggugggc      300

aucaagguga uguacauggg ggaggagcac cucuucuccg ucgagcagau caccgccaug      360

cugcugacga agcucaagga gaccgccgag aacagccuga agaagcccgu gaccgacugc      420

gugaucuccg uccccagcuu cuucaccgac gccgagcggc gcuccgugcu ggacgcggcc      480

cagaucgugg gccucaacug ccugcggcug augaacgaca ugacggccgu cgcccucaac      540

uacgggaucu acaagcagga ccugccgagc cuggacgaga agccccgcau cgugguguuc      600

gucgacaugg gccacuccgc cuuccaggug agcgcgugcg ccuucaacaa gggcaagcuc      660

aaggugcugg ggaccgccuu cgaccccuuc cugggcggga agaacuucga cgagaagcuc      720

gucgagcacu ucugcgccga guucaagacc aaguacaagc uggacgccaa guccaagauc      780

cgggcgcugc uccgccugua ccaggagugc gagaagcuga agaagcucau gagcuccaac      840

agcaccgacc ugccccugaa caucgagugc uucaugaacg acaaggacgu gagcggcaag      900

augaaccggu cccaguucga ggagcucugc gccgagcugc ugcagaagau cgaggugccg      960

cucuacagcc ugcuggagca gacgcaccuc aaggucgagg acguguccgc cgucgagauc     1020

gugggcgggg ccacccgcau ccccgccgug aaggagcgga ucgcgaaguu cuucggcaag     1080

gacaucagca ccacccugaa cgccgacgag gccgucgccc gcgggugcgc ccugcagugc     1140

gcgauccucu cccccgccuu caaggugcgg gaguucagcg ugacggacgc cguccccuuc     1200

ccgaucuccc ugaucuggaa ccacgacagc gaggacaccg agggcgugca cgagguguuc     1260

ucccgcaacc acgccgcgcc cuucagcaag guccugaccu uccuccggcg cgggcccuuc     1320

gagcuggagg ccuucuacuc cgacccccag ggcgugccgu accccgaggc caagaucggc     1380

cgguucgugg uccagaacgu gagcgcccag aaggacgggg agaagucccg cgugaagguc     1440

aaggugcggg ugaacaccca cggcaucuuc acgaucagca ccgccuccau ggucgagaag     1500

gugcccaccg aggagaacga gaugagcucc gaggcggaca uggagugccu gaaccagcgg     1560

cccccggaga accccgacac cgacaagaac gugcagcagg acaacagcga ggccgggacg     1620

cagccccagg uccagaccga cgcccagcag accucccaga gcccgcccag ccccgagcuc     1680

accuccgagg agaacaagau ccccgacgcc gacaaggcca acgagaagaa gguggaccag     1740

cccccggagg cgaagaagcc caagaucaag guggucaacg uggagcugcc caucgaggcc     1800

aaccuggugu ggcagcucgg caaggaccug cugaacaugu acaucgagac ggaggggaag     1860

augaucaugc aggacaagcu cgagaaggag cgcaacgacg ccaagaacgc cgucgaggag     1920

uacguguacg aguuccgcga caagcugugc ggcccguacg agaaguucau cugcgagcag     1980

gaccaccaga acuuccugcg ccugcucacc gagaccgagg acuggcugua cgaggagggc     2040

gaggaccagg ccaagcaggc guacguggac aagcuggagg agcucaugaa gaucgggacc     2100

cccgucaagg ugcgguucca ggaggccgag gagcgcccca agauguucga ggagcugggc     2160

cagcggcugc agcacuacgc caagaucgcc gcggacuucc gcaacaagga cgagaaguac     2220

aaccacaucg acgagagcga gaugaagaag guggagaagu ccgucaacga ggugauggag     2280

uggaugaaca acgugaugaa cgcccaggcc aagaaguccc ucgaccagga ccccgucgug     2340

cgggcccagg agaucaagac gaagaucaag gagcugaaca acacgugcga gccggugguc     2400

acccagccca agcccaagau cgagagcccc aagcuggagc gcaccccgaa cgggcccaac     2460

aucgacaaga aggaggagga ccucgaggac aagaacaacu ucggcgccga gccgccccac     2520

cagaacgggg agugcuaccc caacgagaag aacagcguga acauggaccu ggacuga        2577


<210>  276
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  276
auggccgaca aggugcgccg gcagcgcccc cggcgccggg ucugcugggc ccugguggcg       60

gugcuccugg ccgaccugcu cgcccugagc gacacccugg ccgucauguc cguggaccuc      120

ggcagcgagu ccaugaaggu ggccaucguc aagccggggg ugcccaugga gaucgugcug      180

aacaaggaga gccgccggaa gacccccguc aucgugacgc ugaaggagaa cgagcgcuuc      240

uucggcgacu ccgcggccag cauggccauc aagaacccca aggccacccu ccgguacuuc      300

cagcaccucc uggggaagca ggcggacaac ccgcacgugg cccuguacca ggcccgcuuc      360

cccgagcacg agcugaccuu cgacccccag cggcagaccg uccacuucca gaucuccagc      420

cagcugcagu ucucccccga ggaggugcuc ggcauggugc ugaacuacag ccgcucccug      480

gccgaggacu ucgccgagca gccgaucaag gacgcgguca ucacggugcc cguguucuuc      540

aaccaggccg agcggcgcgc cguccuccag gccgcccgga uggcggggcu gaaggugcug      600

cagcucauca acgacaacac cgccaccgcc cugagcuacg gcguguuccg ccggaaggac      660

aucaacacca cggcccagaa caucauguuc uacgacaugg gcuccgggag caccgucugc      720

accaucguga ccuaccagau ggugaagacg aaggaggccg gcaugcagcc ccagcugcag      780

auccgcgggg ucggcuucga ccggacccuc gggggccugg agauggagcu gcgccuccgg      840

gagcgccugg cgggccuguu caacgagcag cgcaaggggc agcgggccaa ggacgugcgc      900

gagaaccccc gggccauggc caagcuccug cgcgaggcca accggcugaa gaccguccuc      960

uccgcgaacg ccgaccacau ggcccagauc gagggccuga uggacgacgu ggacuucaag     1020

gccaagguga cccgcgucga guucgaggag cugugcgcgg accucuucga gcgggugccg     1080

gggcccgugc agcaggcccu gcagagcgcc gagauguccc uggacgagau cgagcagguc     1140

auccucgugg gcggcgccac gcgcgugccc cggguccagg aggugcugcu gaaggccgug     1200

gggaaggagg agcucggcaa gaacaucaac gcggacgagg ccgccgccau gggggccguc     1260

uaccaggcgg ccgcccugag caaggccuuc aaggugaagc ccuucguggu ccgcgacgcc     1320

gugguguacc cgauccuggu cgaguucacc cgggaggugg aggaggagcc cggcauccac     1380

ucccucaagc acaacaagcg cgugcuguuc agccggaugg ggcccuaccc ccagcgcaag     1440

gucaucaccu ucaaccggua cagccacgac uucaacuucc acaucaacua cggcgaccug     1500

ggcuuccucg ggccggagga ccugcgcgug uucggcuccc agaaccugac cacggugaag     1560

cugaaggggg ucggcgacag cuucaagaag uaccccgacu acgaguccaa ggggaucaag     1620

gcgcacuuca accucgacga gagcggcgug cugucccugg accgggugga gagcgucuuc     1680

gagacccucg uggaggacuc cgccgaggag gagagcaccc ugaccaagcu gggcaacacg     1740

aucuccagcc ucuucggggg cgggaccacc cccgacgcca aggagaacgg caccgacacg     1800

gugcaggagg aggaggaguc ccccgccgag gggagcaagg acgagccggg cgagcagguc     1860

gagcugaagg aggaggcgga ggcccccgug gaggacggcu cccagccgcc gccgcccgag     1920

cccaaggggg acgccacccc cgagggcgag aaggccaccg agaaggagaa cggggacaag     1980

agcgaggccc agaagcccuc cgagaaggcg gaggccggcc ccgagggcgu ggcccccgcc     2040

cccgaggggg agaagaagca gaagcccgcc cgcaagcggc gcauggucga ggagaucggc     2100

guggagcugg ugguccucga ccugcccgac cugcccgagg acaagcucgc gcagagcgug     2160

cagaagcugc aggaccugac ccuccgcgac cuggagaagc aggagcggga gaaggccgcc     2220

aacucccugg aggccuucau cuucgagacg caggacaagc ucuaccagcc ggaguaccag     2280

gaggugagca ccgaggagca gcgcgaggag aucuccggga agcugagcgc cgcgagcacc     2340

uggcuggagg acgagggcgu cggggccacc acggugaugc ucaaggagaa gcuggccgag     2400

cugcggaagc ucugccaggg ccuguucuuc cgcguggagg agcggaagaa guggcccgag     2460

cgccuguccg cccucgacaa ccugcugaac cacagcucca uguuccucaa gggcgcgcgg     2520

cugauccccg agauggacca gaucuucacc gaggucgaga ugaccacccu ggagaaggug     2580

aucaacgaga ccugggccug gaagaacgcc acgcucgccg agcaggccaa gcugcccgcg     2640

accgagaagc cggugcugcu cagcaaggac aucgaggcca agaugauggc ccuggaccgc     2700

gagguccagu accugcucaa caaggccaag uucaccaagc cccggccccg ccccaaggac     2760

aagaacggga cccgggccga gccgccccug aacgcguccg ccagcgacca gggcgagaag     2820

gugaucccgc ccgccgggca gacggaggac gccgagccca ucuccgagcc cgagaaggug     2880

gagaccggca gcgagcccgg ggacaccgag ccccuggagc ucggcggccc gggggccgag     2940

cccgagcaga aggagcaguc caccggccag aagcgccccc ugaagaacga cgagcuguga     3000


<210>  277
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  277
augcccgagg agacccagac ccaggaccag cccauggagg aggaggaggu ggagacguuc       60

gccuuccagg ccgagaucgc gcagcugaug agccucauca ucaacaccuu cuacuccaac      120

aaggagaucu uccugcgcga gcugaucagc aacuccagcg acgcccucga caagauccgg      180

uacgaguccc ugaccgaccc cagcaagcug gacuccggca aggagcucca caucaaccug      240

auccccaaca agcaggaccg cacccugacg aucgucgaca ccgggaucgg caugaccaag      300

gccgaccuca ucaacaaccu ggggaccauc gccaagagcg gcacgaaggc cuucauggag      360

gcgcugcagg ccggggccga caucuccaug aucggccagu ucggcguggg guucuacagc      420

gccuaccucg uggcggagaa ggucaccgug aucaccaagc acaacgacga cgagcaguac      480

gccugggagu ccagcgccgg cggguccuuc accgugcgga cggacaccgg cgagcccaug      540

gggcgcggca ccaaggucau ccugcaccug aaggaggacc agaccgagua ccucgaggag      600

cggcgcauca aggagaucgu gaagaagcac agccaguuca ucggcuaccc gaucacgcug      660

uucguggaga aggagcggga caaggagguc uccgacgacg aggccgagga gaaggaggac      720

aaggaggagg agaaggagaa ggaggagaag gagagcgagg acaagcccga gaucgaggac      780

gugggguccg acgaggagga ggagaagaag gacggcgaca agaagaagaa gaagaagauc      840

aaggagaagu acaucgacca ggaggagcug aacaagacca agcccaucug gacccgcaac      900

cccgacgaca ucaccaacga ggaguacggg gaguucuaca agagccucac gaacgacugg      960

gaggaccacc uggccgugaa gcacuucucc gucgagggcc agcuggaguu ccgggcgcuc     1020

cuguucgugc cgcgccgggc ccccuucgac cuguucgaga accgcaagaa gaagaacaac     1080

aucaagcucu acgugcggcg cgucuucauc auggacaacu gcgaggagcu gauccccgag     1140

uaccugaacu ucauccgggg cgugguggac agcgaggacc ucccccugaa caucagccgc     1200

gagaugcugc agcaguccaa gauccucaag gucauccgga agaaccuggu gaagaagugc     1260

cuggagcugu ucaccgagcu cgccgaggac aaggagaacu acaagaaguu cuacgagcag     1320

uucagcaaga acaucaagcu ggggauccac gaggacuccc agaaccgcaa gaagcucagc     1380

gagcugcugc gguacuacac cuccgccagc ggcgacgaga uggugucccu caaggacuac     1440

ugcacccgca ugaaggagaa ccagaagcac aucuacuaca ucacggggga gaccaaggac     1500

caggucgcca acagcgcguu cguggagcgg cugcgcaagc acggccugga ggugaucuac     1560

augaucgagc cgaucgacga guacugcguc cagcagcuca aggaguucga ggggaagacc     1620

cugguguccg ucaccaagga gggccuggag cuccccgagg acgaggagga gaagaagaag     1680

caggaggaga agaagacgaa guucgagaac cugugcaaga ucaugaagga cauccuggag     1740

aagaaggugg agaagguggu cgugagcaac cgccucguga ccucccccug cugcaucguc     1800

accagcaccu acggcuggac ggccaacaug gagcggauca ugaaggccca ggcccugcgc     1860

gacaacucca ccauggggua cauggccgcg aagaagcacc uggagaucaa ccccgaccac     1920

agcaucaucg agacccugcg gcagaaggcc gaggccgaca agaacgacaa guccgugaag     1980

gaccucguga uccugcugua cgagaccgcc cuccugagcu ccggcuucag ccuggaggac     2040

ccgcagacgc acgccaaccg caucuaccgg augaucaagc ucgggcuggg caucgacgag     2100

gacgacccca ccgcggacga caccuccgcc gccgucaccg aggagaugcc gccccuggag     2160

ggggacgacg acaccagccg cauggaggag guggacuga                            2199


<210>  278
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  278
auggacagcu ccaagcugga cagcggcaag gggcuccaca ucaaccuggu gcccaacaag       60

cagaaccaga cccugaccau cgucgacacg cgcaucggca ugaccaagac cgaccucauc      120

aacaaccugg ggaccgugac gaaguccggc accaaggccu ucauggaggc ccugcaggcg      180

gacgccgaca ucagcaugau cgggcacuuc ggcgugggcu ucuacuccgc cuaccucguc      240

gccaagaagg ugaccgugau cagcaagcac aacaacgacg agcaguacac cugggagucc      300

agcgccgggg gcuccuucac gguccggacc gacgaguga                             339


<210>  279
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  279
augcccgagg aggugcacca cggcgaggag gaggucgaga ccuucgccuu ccaggccgag       60

aucgcgcagc ugaugagccu caucaucaac accuucuacu ccaacaagga gaucuuccug      120

cgcgagcuga ucagcaacgc cuccgacgcc cucgacaaga uccgguacga gagccugacg      180

gacccgucca agcuggacag cgggaaggag cucaagaucg acaucauccc caacccccag      240

gagcgcaccc ugacccuggu ggacaccggc aucgggauga cgaaggccga ccucaucaac      300

aaccugggca ccaucgccaa guccgggacc aaggcguuca uggaggcccu gcaggccggc      360

gccgacauca gcaugaucgg ccaguucggg gugggcuucu acuccgcgua ccucgucgcc      420

gagaaggugg uggucaucac caagcacaac gacgacgagc aguacgccug ggagagcucc      480

gccgggggca gcuucacggu gcgggccgac cacggggagc ccaucggccg cggcaccaag      540

gugauccugc accugaagga ggaccagacc gaguaccucg aggagcggcg cgucaaggag      600

guggugaaga agcacuccca guucaucggg uacccgauca cccuguaccu ggagaaggag      660

cgggagaagg agaucagcga cgacgaggcg gaggaggaga agggcgagaa ggaggaggag      720

gacaaggacg acgaggagaa gcccaagauc gaggacgucg gguccgacga ggaggacgac      780

agcggcaagg acaagaagaa gaagacgaag aagaucaagg agaaguacau cgaccaggag      840

gagcucaaca agaccaagcc caucuggacc cgcaaccccg acgacaucac ccaggaggag      900

uacggcgagu ucuacaaguc ccugacgaac gacugggagg accaccuggc cgugaagcac      960

uucagcgugg aggggcagcu cgaguuccgg gcccugcugu ucaucccgcg ccgggccccc     1020

uucgaccucu ucgagaacaa gaagaagaag aacaacauca agcuguacgu ccgccgggug     1080

uucaucaugg acuccugcga cgagcugauc cccgaguacc ucaacuucau ccgcggcgug     1140

gucgacagcg aggaccugcc ccugaacauc agccgggaga ugcuccagca guccaagauc     1200

cugaagguga uccgcaagaa caucgugaag aagugccugg agcuguucag cgagcucgcc     1260

gaggacaagg agaacuacaa gaaguucuac gaggcguucu ccaagaaccu gaagcucggg     1320

auccacgagg acagcaccaa ccggcgccgg cuguccgagc ugcuccgcua ccacaccagc     1380

caguccggcg acgagaugac cagccugucc gaguacguca gccggaugaa ggagacgcag     1440

aaguccaucu acuacaucac cggggagagc aaggagcagg ucgccaacuc cgccuucgug     1500

gagcgcgugc gcaagcgggg cuucgaggug gucuacauga ccgagccgau cgacgaguac     1560

ugcgugcagc agcugaagga guucgacggc aagagccucg uguccgucac caaggagggg     1620

cuggagcugc ccgaggacga ggaggagaag aagaagaugg aggagagcaa ggccaaguuc     1680

gagaaccucu gcaagcugau gaaggagauc cuggacaaga agguggagaa ggugacgauc     1740

uccaaccgcc ucgucagcuc ccccugcugc aucgugacca gcaccuacgg cuggaccgcc     1800

aacauggagc ggaucaugaa ggcgcaggcc cugcgcgaca acagcacgau gggguacaug     1860

auggccaaga agcaccugga gaucaacccc gaccacccga ucguggagac ccugcggcag     1920

aaggccgagg ccgacaagaa cgacaaggcg gucaaggacc ucguggugcu gcuguucgag     1980

accgcccucc uguccagcgg cuucucccug gaggaccccc agacccacag caaccgcauc     2040

uaccggauga ucaagcucgg gcugggcauc gacgaggacg aggucgccgc cgaggagccc     2100

aacgcggccg ugcccgacga gaucccgccc cuggagggcg acgaggacgc cucccgcaug     2160

gaggaggugg acuga                                                      2175


<210>  280
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  280
augcgcgccc ugugggugcu cggccugugc ugcguccugc ucaccuucgg gagcgugcgg       60

gccgacgacg agguggacgu cgacggcacc guggaggagg accuggggaa gucccgcgag      120

ggcagccgga cggacgacga ggugguccag cgcgaggagg aggcgaucca gcuggacggg      180

cucaacgccu cccagauccg ggagcugcgc gagaaguccg agaaguucgc cuuccaggcc      240

gaggugaacc ggaugaugaa gcugaucauc aacagccucu acaagaacaa ggagaucuuc      300

cugcgcgagc ugaucagcaa cgccuccgac gcgcucgaca agauccggcu gaucagccug      360

accgacgaga acgcccucuc cggcaacgag gagcugaccg ugaagaucaa gugcgacaag      420

gagaagaacc ugcuccacgu caccgacacg ggcgugggga ugacccgcga ggagcuggug      480

aagaaccugg gcaccaucgc caagagcggg accuccgagu uccucaacaa gaugacggag      540

gcccaggagg acggccagag caccuccgag cugaucgggc aguucggcgu cggcuucuac      600

agcgcguucc ugguggccga caaggugauc gucaccucca agcacaacaa cgacacccag      660

cacaucuggg agagcgacuc caacgaguuc agcgugaucg ccgacccccg ggggaacacg      720

cucggccgcg ggaccaccau cacccuggug cugaaggagg aggccuccga cuaccucgag      780

cuggacacga ucaagaaccu ggucaagaag uacagccagu ucaucaacuu cccgaucuac      840

guguggagcu ccaagaccga gaccguggag gagcccaugg aggaggagga ggccgcgaag      900

gaggagaagg aggagagcga cgacgaggcc gccgucgagg aggaggagga ggagaagaag      960

cccaagacca agaaggugga gaagacggug ugggacuggg agcucaugaa cgacaucaag     1020

cccaucuggc agcggccguc caaggagguc gaggaggacg aguacaaggc cuucuacaag     1080

agcuucucca aggagagcga cgaccccaug gccuacaucc acuucaccgc ggagggcgag     1140

gugaccuuca aguccauccu guucgucccc accagcgcgc cccgcggccu guucgacgag     1200

uacgggucca agaaguccga cuacaucaag cucuacgugc ggcgcguguu caucacggac     1260

gacuuccacg acaugaugcc gaaguaccug aacuucguca agggcguggu ggacagcgac     1320

gaccugcccc ucaacgucag ccgggagacc cugcagcagc acaagcugcu caaggugauc     1380

cgcaagaagc uggugcggaa gacccuggac augaucaaga agaucgccga cgacaaguac     1440

aacgacaccu ucuggaagga guucgggacg aacaucaagc ucggcgucau cgaggaccac     1500

uccaaccgca cccggcuggc caagcugcuc cgcuuccaga gcucccacca ccccaccgac     1560

aucaccagcc uggaccagua cguggagcgc augaaggaga agcaggacaa gaucuacuuc     1620

auggccgggu ccagccggaa ggaggccgag uccagccccu ucguggagcg ccugcucaag     1680

aagggcuacg aggucaucua ccugacggag ccgguggacg aguacugcau ccaggcccug     1740

cccgaguucg acggcaagcg guuccagaac guggccaagg agggggucaa guucgacgag     1800

agcgagaaga ccaaggaguc ccgcgaggcc guggagaagg aguucgagcc ccugcucaac     1860

uggaugaagg acaaggcccu gaaggacaag aucgagaagg cgguggucag ccagcggcug     1920

accgaguccc ccugcgcccu cguggccagc caguacggcu gguccgggaa cauggagcgc     1980

aucaugaagg cccaggcgua ccagaccggc aaggacauca gcacgaacua cuacgccucc     2040

cagaagaaga ccuucgagau caacccgcgg cacccccuga uccgcgacau gcugcggcgc     2100

aucaaggagg acgaggacga caagaccgug cucgaccugg ccgucgugcu guucgagacc     2160

gccacccucc ggagcgggua ccugcugccc gacacgaagg ccuacggcga ccgcaucgag     2220

cggaugcucc gccugucccu gaacaucgac cccgacgcga agguggagga ggagccggag     2280

gaggagcccg aggagaccgc cgaggacacc accgaggaca cggagcagga cgaggacgag     2340

gagauggacg ucggcaccga cgaggaggag gagaccgcca aggagagcac cgccgagaag     2400

gacgagcucu ga                                                         2412


<210>  281
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  281
auggcccgcg agcugcgggc ccuccugcug uggggccgcc ggcuccgccc ccugcugcgg       60

gcgccggccc ucgccgccgu gcccgggggc aagcccaucc ugugcccccg ccggaccacc      120

gcccagcugg ggccgcgccg gaaccccgcg uggagccucc aggccggccg ccuguucucc      180

acgcagaccg ccgaggacaa ggaggagccc cugcacagca ucaucuccag caccgagucc      240

guccagggga gcaccuccaa gcacgaguuc caggccgaga cgaagaagcu ccuggacauc      300

guggcgcgga gccuguacuc cgagaaggag guguucaucc gcgagcucau cagcaacgcc      360

uccgacgccc uggagaagcu gcggcacaag cucgucagcg acggccaggc ccugcccgag      420

auggagaucc accuccagac caacgccgag aagggcacca ucaccaucca ggacacgggg      480

aucggcauga cccaggagga gcuggugucc aaccugggga ccaucgcgcg cagcggcucc      540

aaggccuucc uggacgcccu ccagaaccag gccgaggcca gcuccaagau caucgggcag      600

uucggcgugg gcuucuacag cgcguucaug gucgccgacc ggguggaggu guacucccgc      660

agcgccgccc cggggagccu gggcuaccag uggcuguccg acgggagcgg cgucuucgag      720

aucgccgagg cguccggcgu gcggaccggg acgaagauca ucauccaccu caagagcgac      780

ugcaaggagu ucuccagcga ggcccgcgug cgggacgucg ugaccaagua cuccaacuuc      840

gugagcuucc cccuguaccu gaacggccgc cggaugaaca cccuccaggc caucuggaug      900

auggacccca aggacguccg cgaguggcag cacgaggagu ucuaccgcua cguggcccag      960

gcccacgaca agccccggua cacccugcac uacaagacgg acgcgccgcu gaacauccgc     1020

uccaucuucu acgugcccga caugaagccc agcauguucg acgucucccg ggagcucggg     1080

agcuccgugg cccuguacag ccgcaaggug cugauccaga ccaaggccac cgacauccuc     1140

cccaaguggc ugcgguucau ccgcggcguc guggacuccg aggacauccc gcugaaccuc     1200

agccgggagc ugcugcagga guccgcccuc auccgcaagc ugcgggacgu gcugcagcag     1260

cgccucauca aguucuucau cgaccagagc aagaaggacg cggagaagua cgccaaguuc     1320

uucgaggacu acgggcuguu caugcgggag ggcaucguca ccgccacgga gcaggaggug     1380

aaggaggaca ucgccaagcu gcuccgcuac gaguccagcg cccugcccag cggccagcug     1440

accucccuga gcgaguacgc gucccggaug cgcgccggga cccggaacau cuacuaccuc     1500

ugcgccccca accgccaccu ggccgagcac agccccuacu acgaggccau gaagaagaag     1560

gacaccgagg uccuguucug cuucgagcag uucgacgagc ucacgcugcu gcaccuccgg     1620

gaguucgaca agaagaagcu gaucuccgug gagaccgaca ucguggucga ccacuacaag     1680

gaggagaagu ucgaggaccg cagcccggcg gccgagugcc uguccgagaa ggagaccgag     1740

gagcucaugg ccuggaugcg gaacgugcug ggcagccgcg ugaccaacgu caaggugacg     1800

cugcgccucg acacccaccc cgccauggug accguccugg agaugggggc cgcgcggcac     1860

uuccugcgca ugcagcagcu cgccaagacc caggaggagc gggcccagcu gcugcagccc     1920

acgcucgaga ucaacccccg ccacgcccug aucaagaagc ugaaccagcu ccgggcgucc     1980

gagccgggcc uggcccagcu gcucguggac cagaucuacg agaacgccau gaucgccgcc     2040

gggcuggugg acgacccccg cgcgaugguc ggccggcuga acgagcuccu ggugaaggcc     2100

cuggagcgcc acuga                                                      2115


<210>  282
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  282
augggcaaga ucagcucccu gcccacccag cuguucaagu gcugcuucug cgacuuccuc       60

aaggugaaga ugcacaccau gagcuccagc caccuguucu accucgcccu gugccugcuc      120

acguucaccu ccagcgccac cgcggggccg gagacccugu gcggcgccga gcuggucgac      180

gcccuccagu ucgugugcgg ggaccgcggc uucuacuuca acaagcccac gggguacggc      240

uccagcuccc ggcgcgcgcc ccagaccggc aucguggacg agugcugcuu ccggagcugc      300

gaccugcgcc ggcuggagau guacugcgcg ccccucaagc cggccaaguc cgcccgcagc      360

guccgggccc agcgccacac cgacaugccc aagacccaga aggaggugca ccugaagaac      420

gccucccggg ggagcgccgg caacaagaac uaccgcaugu ga                         462


<210>  283
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  283
augggcaucc ccauggggaa guccaugcug gugcuccuga ccuuccuggc cuucgccagc       60

ugcugcaucg cggccuaccg cccgagcgag acccucugcg gcggggagcu ggucgacacg      120

cugcaguucg ugugcggcga ccggggguuc uacuucuccc gccccgccag ccgggugucc      180

cgccggagcc gcggcaucgu cgaggagugc ugcuuccggu ccugcgaccu cgcccugcug      240

gagaccuacu gcgccacccc cgccaagagc gagcgcgacg uguccacgcc cccgaccgug      300

cuccccgaca acuucccccg guaccccguc ggcaaguucu uccaguacga caccuggaag      360

cagagcaccc agcgccugcg gcgcgggcug ccggcgcucc ugcgggcccg ccggggccac      420

gugcuggcca aggagcucga ggcguuccgc gaggccaagc ggcaccgccc ccugaucgcc      480

cugcccaccc aggaccccgc ccacgggggc gccccgcccg agauggcguc caaccggaag      540

uga                                                                    543


<210>  284
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  284
augaacagcu ucuccaccag cgccuucggc cccguggccu ucucccuggg gcuccugcug       60

guccucccgg cggccuuccc cgcccccgug cccccgggcg aggacagcaa ggacguggcc      120

gcgccccacc gccagccccu gaccuccagc gagcggaucg acaagcagau ccgcuacauc      180

cuggacggga ucuccgcccu ccggaaggag acgugcaaca agagcaacau gugcgagucc      240

agcaaggagg cccuggccga gaacaaccug aaccucccca agauggccga gaaggacggc      300

ugcuuccagu ccggguucaa cgaggagacc ugccugguca agaucaucac cggccugcuc      360

gaguucgagg uguaccugga guaccugcag aaccgcuucg agagcuccga ggagcaggcg      420

cgggccgugc agaugagcac caagguccuc auccaguucc ugcagaagaa ggccaagaac      480

cuggacgcca ucacgacccc ggaccccacc accaacgccu cccuccugac gaagcugcag      540

gcgcagaacc aguggcucca ggacaugacc acccaccuga uccugcgcag cuucaaggag      600

uuccuccagu ccagccugcg ggcccugcgc cagauguga                             639


<210>  285
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  285
augccccugc ucuggcugcg cggcuuccug cucgccagcu gcuggaucau cgugcggucc       60

agcccgaccc ccggguccga gggccacagc gccgcgcccg acugccccuc cugcgcccug      120

gccgcccugc cgaaggacgu ccccaacagc cagcccgaga ugguggaggc cgugaagaag      180

cacauccuca acaugcugca ccugaagaag cgccccgacg ucacccagcc ggugcccaag      240

gcggcccucc ugaacgccau ccggaagcug cacgugggga aggucggcga gaacggguac      300

guggagaucg aggacgacau cggccgccgg gccgagauga acgagcucau ggagcagacg      360

uccgagauca ucaccuucgc ggagagcggc accgcccgca agacccugca cuucgagauc      420

uccaaggagg ggagcgaccu guccgugguc gagcgggccg agguguggcu guuccucaag      480

gugcccaagg ccaaccgcac gcggaccaag gucaccaucc gccuguucca gcagcagaag      540

cacccccagg gcagccucga caccggggag gaggccgagg aggugggccu gaagggggag      600

cgguccgagc ugcuccugag cgagaaggug gucgacgcgc gcaaguccac guggcacgug      660

uucccgguga gcuccagcau ccagcggcug cucgaccagg gcaaguccag ccuggacguc      720

cgcaucgccu gcgagcagug ccaggagagc ggcgccuccc uggugcuccu ggggaagaag      780

aagaagaagg aggaggaggg cgaggggaag aagaagggcg gcggggaggg cggggccggc      840

gccgacgagg agaaggagca gagccaccgg cccuuccuga ugcuccaggc gcgccagucc      900

gaggaccacc cccaccggcg ccggcgccgg gggcuggagu gcgacggcaa ggugaacauc      960

ugcugcaaga agcaguucuu cgucagcuuc aaggacaucg gcuggaacga cuggaucauc     1020

gcccccuccg gguaccacgc caacuacugc gagggcgagu gcccgagcca caucgccggg     1080

accuccggca gcucccugag cuuccacucc accgugauca accacuaccg caugcgcggg     1140

cacagccccu ucgccaaccu caaguccugc ugcgugccca ccaagcugcg gcccaugagc     1200

augcuguacu acgacgacgg ccagaacauc aucaagaagg acauccagaa caugaucguc     1260

gaggagugcg gcugcuccug a                                               1281


<210>  286
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  286
auggacggcc ugcccgggcg cgcccucggc gccgcgugcc ugcugcuccu ggccgccggg       60

uggcugggcc cggaggccug ggggagcccc accccgcccc cgacccccgc cgcgcccccg      120

cccccgcccc cgcccggcuc ccccggcggg agccaggaca cgugcaccuc cugcggcggg      180

uuccggcgcc ccgaggagcu cggccgggug gacggggacu uccuggaggc cgucaagcgc      240

cacauccuga gccggcucca gaugcgcggc cggcccaaca ucacccacgc cgugcccaag      300

gccgcgaugg ugaccgcccu gcgcaagcug cacgccggca agguccggga ggacgggcgc      360

guggagaucc cccaccucga cggccacgcc ucccccgggg ccgacggcca ggagcgggug      420

agcgagauca ucuccuucgc ggagacggac ggccuggcca gcucccgcgu ccggcuguac      480

uucuucauca gcaacgaggg gaaccagaac cucuucgugg ugcaggccuc ccuguggcug      540

uaccucaagc ugcugcccua cguccucgag aagggcagcc gccggaaggu gcgcgugaag      600

gucuacuucc aggagcaggg gcacggcgac cgguggaaca ugguggagaa gcgcguggac      660

cugaagcggu ccggguggca caccuucccc cugaccgagg ccauccaggc ccucuucgag      720

cgcggcgagc ggcgccugaa ccuggacguc cagugcgaca gcugccagga gcucgcggug      780

gugcccgucu ucguggaccc cggcgaggag ucccaccgcc ccuucguggu cgugcaggcc      840

cggcuggggg acagccgcca ccggauccgc aagcggggcc uggagugcga cgggcgcacc      900

aaccucugcu gccggcagca guucuucauc gacuuccgcc ugaucggcug gaacgacugg      960

aucaucgccc cgacggggua cuacggcaac uacugcgagg gcuccugccc cgccuaccug     1020

gccggggugc ccggcagcgc guccagcuuc cacaccgccg ucgugaacca guaccggaug     1080

cgcgggcuca accccggcac cgucaacagc ugcugcaucc cgaccaagcu guccacgaug     1140

agcaugcugu acuucgacga cgaguacaac aucgugaagc gggacgugcc caacaugauc     1200

gucgaggagu gcgggugcgc cuga                                            1224


<210>  287
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  287
auggcccugc gcgugcuccu gcugaccgcc cucacccugu gccacggcuu caaccuggac       60

acggagaacg cgaugaccuu ccaggagaac gcccgggggu ucggccagag cgucgugcag      120

cuccaggggu cccgcguggu cgugggcgcc ccccaggaga ucguggccgc caaccagcgg      180

gggagccugu accagugcga cuacuccacc ggcagcugcg agccgauccg ccugcagguc      240

cccguggagg cggugaacau gucccucggc cugagccugg ccgccaccac gucccccccc      300

cagcuccugg ccugcgggcc gaccguccac cagaccugca gcgagaacac cuacgugaag      360

ggccugugcu uccucuucgg guccaaccug cggcagcagc cccagaaguu ccccgaggcg      420

cugcgcggcu gcccccagga ggacagcgac aucgccuucc ucaucgacgg guccggcagc      480

aucaucccgc acgacuuccg gcgcaugaag gaguucgugu ccacggucau ggagcagcug      540

aagaagucca agacccuguu cucccucaug caguacagcg aggaguuccg gauccacuuc      600

accuucaagg aguuccagaa caaccccaac ccccgcuccc uggugaagcc caucacccag      660

cugcucggcc ggacgcacac cgccaccggg auccgcaagg ugguccggga gcuguucaac      720

aucaccaacg gcgcccgcaa gaacgccuuc aagauccugg uggugaucac ggacggggag      780

aaguucggcg acccgcucgg cuacgaggac gucauccccg aggcggaccg ggagggggug      840

auccgcuacg ugaucggcgu cggggacgcc uuccggagcg agaagucccg ccaggagcug      900

aacaccaucg ccagcaagcc cccccgggac cacguguucc aggugaacaa cuucgaggcc      960

cugaagacca uccagaacca gcuccgcgag aagaucuucg ccaucgaggg cacccagacg     1020

gggagcucca gcuccuucga gcacgagaug agccaggagg gcuucuccgc ggccaucacc     1080

agcaacggcc cgcugcuguc caccgucggg agcuacgacu gggccggcgg gguguuccuc     1140

uacaccucca aggagaaguc cacguucauc aacaugaccc gggucgacuc cgacaugaac     1200

gacgccuacc ugggcuacgc cgcggccauc auccugcgca accgcgugca gagccucgug     1260

cugggggccc cccgguacca gcacaucggc cuggucgcca uguuccgcca gaacaccggc     1320

augugggagu ccaacgccaa cgugaagggg acccagaucg gcgcguacuu cggggccagc     1380

cucugcuccg uggacgucga cagcaacggc uccacggacc uggugcugau cggggccccc     1440

cacuacuacg agcagacccg gggcggccag gugagcgucu gcccccuccc gcgcgggcgg     1500

gcccgcuggc agugcgacgc ggugcuguac ggcgagcagg ggcagcccug gggccgguuc     1560

ggcgccgccc ugaccgugcu cggggacguc aacggcgaca agcugaccga cguggccauc     1620

ggggcccccg gcgaggagga caaccgcggg gcgguguacc uguuccacgg cacguccggc     1680

agcgggauca gccccuccca cagccagcgg aucgccggcu ccaagcucag cccgcgccug     1740

caguacuucg ggcagucccu gagcggcggg caggaccuga ccauggacgg ccucgucgac     1800

cugaccgugg gcgcccaggg gcacgugcug cuccugcggu cccagcccgu ccugcgcgug     1860

aaggccauca uggaguucaa cccccgggag guggcccgca acgucuucga gugcaacgac     1920

caggugguga agggcaagga ggcgggggag guccgggugu gccuccacgu gcagaagucc     1980

acccgcgacc ggcugcgcga gggccagauc caguccgucg ugacguacga ccuggcccuc     2040

gacagcgggc ggccccacuc ccgcgccgug uucaacgaga ccaagaacag cacccgccgg     2100

cagacccagg uccugggccu gacccagacg ugcgagaccc ucaagcugca gcugccgaac     2160

ugcaucgagg accccguguc ccccaucgug cuccgccuga acuucagccu ggucggcacc     2220

ccgcucuccg ccuucgggaa ccugcggccc gugcuggccg aggacgcgca gcgccucuuc     2280

accgcccugu uccccuucga gaagaacugc ggcaacgaca acaucugcca ggacgaccug     2340

agcaucacgu ucuccuucau gagccucgac ugccuggugg ucgggggccc ccgggaguuc     2400

aacgugaccg ugaccguccg caacgacggg gaggacagcu accggaccca ggugacguuc     2460

uucuucccgc uggaccucuc cuaccgcaag gugagcaccc ugcagaacca gcggucccag     2520

cgcagcuggc ggcuggccug cgaguccgcc agcuccaccg aggucagcgg cgcgcucaag     2580

uccaccagcu gcuccaucaa ccaccccauc uuccccgaga acagcgaggu gacguucaac     2640

aucaccuucg acguggacuc caaggccagc cugggcaaca agcugcuccu gaaggccaac     2700

gucaccuccg agaacaacau gccccgcacc aacaagacgg aguuccagcu ggagcucccg     2760

gugaaguacg ccguguacau ggucgugacc agccacgggg uguccaccaa guaccugaac     2820

uucaccgcca gcgagaacac gucccggguc augcagcacc aguaccaggu gagcaaccug     2880

ggccagcgca gccuccccau cucccugguc uuccuggugc ccgugcggcu caaccagacc     2940

gucaucuggg accgccccca ggugaccuuc agcgagaacc uguccagcac augccacacg     3000

aaggagcggc ugccguccca cagcgacuuc cucgcggagc ugcgcaaggc ccccgugguc     3060

aacugcucca ucgccgugug ccagcggauc cagugcgaca uccccuucuu cgggauccag     3120

gaggaguuca acgccacccu gaagggcaac cucagcuucg acugguacau caagaccucc     3180

cacaaccacc uccugaucgu gagcaccgcc gagauccucu ucaacgacuc cgucuucacg     3240

cugcugcccg gccagggggc guucgugcgc agccagaccg agaccaaggu ggagccguuc     3300

gaggucccca acccccuccc ccugaucgug ggcuccagcg uggggggccu gcuccugcug     3360

gcccucauca ccgccgcccu guacaagcug ggguucuuca agcggcagua caaggacaug     3420

auguccgagg gcggcccgcc cggggccgag ccccaguga                            3459


<210>  288
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  288
auguucagcc ugaagacccu ccccuuccug cugcuccugc acgugcagau cuccaaggcc       60

uucccgguca gcuccaagga gaagaacacc aagacggugc aggacuaccu ggagaaguuc      120

uaccagcucc ccagcaacca guaccagucc acccgcaaga acggcaccaa cgugaucguc      180

gagaagcuga aggagaugca gcgguucuuc gggcugaacg ugaccggcaa gcccaacgag      240

gagacgcucg acaugaugaa gaagccccgc ugcggggugc cggacagcgg cggguucaug      300

cugacccccg gcaaccccaa gugggagcgg accaaccuga ccuaccgcau ccggaacuac      360

acgccccagc ucuccgaggc cgaggucgag cgcgcgauca aggacgccuu cgagcugugg      420

agcguggccu ccccgcugau cuucacccgg aucagccagg gcgaggccga caucaacauc      480

gccuucuacc agcgcgacca cggggacaac ucccccuucg acggccccaa cgggauccuc      540

gcgcacgccu uccagcccgg ccaggggauc ggcggcgacg cccacuucga cgccgaggag      600

accuggacca acacgagcgc gaacuacaac cuguuccugg uggccgccca cgaguucggg      660

cacucccucg gccuggccca cagcuccgac ccgggggccc ugauguaccc caacuacgcg      720

uuccgggaga ccagcaacua cucccucccc caggacgaca ucgacggcau ccaggccauc      780

uacggccuga gcuccaaccc cauccagccg accgggccca gcacccccaa gcccugcgac      840

ccgagccuga cguucgacgc caucaccacc cuccgcggcg agauccuguu cuucaaggac      900

cgguacuucu ggcgccggca cccccagcug cagcgcgucg agaugaacuu caucucccuc      960

uucuggccca gccugcccac cgggauccag gccgccuacg aggacuucga ccgggaccug     1020

aucuuccucu ucaagggcaa ccaguacugg gcgcuguccg gguacgacau ccugcagggc     1080

uacccgaagg acaucagcaa cuacggcuuc cccuccagcg ugcaggccau cgacgccgcc     1140

guguucuacc gcuccaagac guacuucuuc gucaacgacc aguucuggcg guacgacaac     1200

cagcgccagu ucauggagcc cggguacccc aagagcaucu ccggcgccuu cccggggauc     1260

gagagcaagg uggacgcggu guuccagcag gagcacuucu uccacgucuu cuccggcccc     1320

cgguacuacg ccuucgaccu caucgcccag cgcgugaccc ggguggcccg cgggaacaag     1380

uggcugaacu gccgcuacgg cuga                                            1404


<210>  289
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  289
augagccugu ggcagccccu cgugcugguc cugcucgugc ugggcugcug cuucgccgcc       60

ccgcgccagc ggcaguccac ccugguccuc uuccccgggg accugcgcac caaccugacg      120

gaccggcagc ucgcggagga guaccuguac cgcuacggcu acacccgggu ggccgagaug      180

cgcggggaga gcaagucccu gggccccgcc cuccugcugc uccagaagca gcugagccug      240

cccgagaccg gggagcucga cuccgccacc cugaaggcca ugcggacgcc gcgcugcggc      300

gugcccgacc ugggccgguu ccagaccuuc gagggggacc ucaaguggca ccaccacaac      360

aucaccuacu ggauccagaa cuacagcgag gaccugcccc gcgcggugau cgacgacgcc      420

uucgcccggg ccuucgcgcu gugguccgcc gucacgcccc ucaccuucac ccgcguguac      480

agccgggacg ccgacaucgu gauccaguuc ggcgucgccg agcacgggga cggcuacccg      540

uucgacggga aggacggccu gcuggcccac gcguucccgc ccggccccgg gauccagggc      600

gacgcccacu ucgacgacga cgagcucugg ucccugggga agggcguggu gguccccacc      660

cgcuucggca acgccgacgg ggccgccugc cacuuccccu ucaucuucga gggccggagc      720

uacuccgcgu gcaccacgga cgggcgcagc gacggccugc ccuggugcuc caccaccgcc      780

aacuacgaca ccgacgaccg guucggguuc ugccccagcg agcgccucua cacgcaggac      840

ggcaacgccg acggcaagcc gugccaguuc cccuucaucu uccaggggca guccuacagc      900

gccugcacca ccgacggccg guccgacggg uaccgcuggu gcgccaccac ggcgaacuac      960

gaccgggaca agcuguucgg cuucugcccc acccgcgccg acagcaccgu gaugggcggc     1020

aacuccgccg gcgagcugug cguguucccc uucaccuucc ucgggaagga guacagcacg     1080

ugcaccagcg agggccgcgg ggacggccgg cuguggugcg ccaccaccuc caacuucgac     1140

agcgacaaga aguggggguu cugcccggac cagggcuacu cccuguuccu cgucgccgcg     1200

cacgaguucg gccacgcccu ggggcuggac cacagcuccg ugcccgaggc ccucauguac     1260

cccauguacc gcuucacgga ggggcccccg cugcacaagg acgacgugaa cgggauccgg     1320

caccuguacg gcccccgccc cgagcccgag ccgcggccgc ccaccaccac cacgccccag     1380

cccaccgccc cgcccaccgu cugccccacc ggcccgccca cggugcaccc cagcgagcgc     1440

cccaccgcgg ggcccaccgg cccgcccucc gccgggccca ccggcccgcc caccgccggg     1500

cccagcacgg ccaccaccgu gccccucucc cccgucgacg acgccugcaa cgugaacauc     1560

uucgacgcga ucgccgagau cggcaaccag cuguaccugu ucaaggacgg caaguacugg     1620

cgguucagcg aggggcgcgg cucccggccc caggggcccu uccucaucgc cgacaagugg     1680

ccggcccugc cccgcaagcu ggacagcgug uucgaggagc ggcucuccaa gaagcuguuc     1740

uucuucagcg gccgccaggu cuggguguac accggggccu ccguccuggg cccccggcgc     1800

cuggacaagc ucggccuggg ggcggacgug gcccagguga cgggcgcccu gcggagcggg     1860

cgcggcaaga ugcuccuguu cuccgggcgg cgccuguggc gguucgacgu caaggcccag     1920

augguggacc cccgcagcgc cuccgaggug gaccgcaugu ucccgggcgu cccccucgac     1980

acccacgacg uguuccagua ccgggagaag gcguacuucu gccaggaccg cuucuacugg     2040

cgggugagca gccgcuccga gcugaaccag gucgaccagg ugggcuacgu gaccuacgac     2100

auccugcagu gccccgagga cuga                                            2124


<210>  290
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  290
augcaccccg gcgugcuggc cgccuuccuc uuccugagcu ggacccacug ccgcgcgcug       60

ccgcuccccu ccgggggcga cgaggacgac cugagcgagg aggaccugca guucgccgag      120

cgguaccucc gcuccuacua ccaccccacc aaccuggccg ggauccugaa ggagaacgcc      180

gccagcucca ugacggagcg gcuccgcgag augcagagcu ucuucggccu ggaggucacc      240

gggaagcugg acgacaacac ccucgacgug augaagaagc cccggugcgg cgugccggac      300

gucggcgagu acaacguguu cccccgcacc cugaaguggu ccaagaugaa ccugacguac      360

cggaucguga acuacacccc cgacaugacc cacagcgagg ucgagaaggc guucaagaag      420

gccuucaagg ugugguccga cgugacgccc cucaacuuca cccgccugca cgacgggauc      480

gccgacauca ugaucagcuu cggcaucaag gagcacgggg acuucuaccc guucgacggc      540

cccuccgggc ugcucgccca cgcguucccg cccggcccca acuacggcgg ggacgcccac      600

uucgacgacg acgagaccug gaccagcucc agcaagggcu acaaccuguu ccuggucgcc      660

gcccacgagu ucgggcacuc ccucggccug gaccacagca aggaccccgg cgcccugaug      720

uuccccaucu acaccuacac ggggaagucc cacuucaugc uccccgacga cgacgugcag      780

ggcauccaga gccuguacgg gccgggcgac gaggacccca accccaagca ccccaagacc      840

ccggacaagu gcgaccccuc ccugagccuc gacgcgauca ccagccugcg cggggagacc      900

augaucuuca aggaccgguu cuucuggcgg cugcaccccc agcaggucga cgccgagcug      960

uuccugacga aguccuucug gcccgagcug ccgaaccgca ucgacgccgc cuacgagcac     1020

cccagccacg accucaucuu caucuuccgg ggccgcaagu ucugggcccu gaacggcuac     1080

gacauccugg agggguaccc caagaagauc uccgagcucg gccugcccaa ggaggugaag     1140

aagaucagcg cggccgugca cuucgaggac accgggaaga cccuccucuu cuccggcaac     1200

cagguguggc gguacgacga caccaaccac aucauggaca aggacuaccc gcgccugauc     1260

gaggaggacu uccccgggau cggcgacaag gucgacgccg uguacgagaa gaacggcuac     1320

aucuacuucu ucaacgggcc cauccaguuc gaguacagca ucugguccaa ccggaucgug     1380

cgcgucaugc cggccaacag cauccugugg ugcuga                               1416


<210>  291
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  291
auggagaccc ccaacaccac ggaggacuac gacaccacca ccgaguucga cuacggcgac       60

gccacgccgu gccagaaggu gaacgagcgc gccuucgggg cgcagcugcu cccgccccug      120

uacagccugg ucuucgugau cggccucgug gggaacaucc uggucgugcu ggugcucguc      180

caguacaagc ggcugaagaa caugaccucc aucuaccugc ucaaccuggc caucagcgac      240

cuccucuucc uguucacccu gcccuucugg aucgacuaca agcucaagga cgacugggug      300

uucggcgacg ccaugugcaa gauccugucc ggguucuacu acaccggccu guacagcgag      360

aucuucuuca ucauccuccu gacgaucgac cgcuaccugg ccaucgugca cgccgucuuc      420

gcgcuccggg cccgcaccgu gaccuucggc gugaucaccu ccaucaucau cugggcccug      480

gccauccugg cgagcaugcc cgggcucuac uucuccaaga cgcaguggga guucacccac      540

cacacgugca gccugcacuu cccccacgag ucccugcggg aguggaagcu guuccaggcc      600

cugaagcuga accucuucgg ccugguccug ccccuccugg ugaugaucau cugcuacacc      660

gggaucauca agauccugcu ccgccggccc aacgagaaga aguccaaggc cgugcgccug      720

aucuucguca ucaugaucau cuucuuccug uucuggaccc cguacaaccu caccauccug      780

aucagcgugu uccaggacuu ccuguucacc cacgagugcg agcagagccg gcaccucgac      840

cuggccgugc aggucaccga ggugaucgcc uacacgcacu gcugcgugaa ccccgucauc      900

uacgcguucg ugggcgagcg cuuccggaag uaccugcgcc agcuguucca ccggcgcgug      960

gccguccacc ucgugaagug gcugcccuuc cucuccgucg accggcugga gcgcgugagc     1020

uccaccagcc ccuccaccgg ggagcacgag cugagcgccg gcuucuga                  1068


<210>  292
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  292
augcgcaccc uggccugccu ccugcugcuc ggcugcgggu accuggccca cgugcuggcg       60

gaggaggccg agaucccccg ggaggugauc gagcgccucg cccggagcca gauccacucc      120

auccgcgacc ugcagcggcu gcucgagauc gacagcgugg gcuccgagga cagccuggac      180

accucccugc gcgcccacgg ggugcacgcc acgaagcacg ucccggagaa gcggccccuc      240

cccauccgcc ggaagcgcag caucgaggag gcggugcccg ccgugugcaa gacccggacc      300

gucaucuacg agaucccgcg cucccaggug gaccccacca gcgccaacuu ccugaucugg      360

ccgcccugcg uggaggucaa gcggugcacg ggcugcugca acaccuccag cgugaagugc      420

cagcccuccc gcgugcacca ccggagcguc aagguggcca agguggagua cguccgcaag      480

aagcccaagc ugaaggaggu ccaggugcgg cucgaggagc accuggagug cgcgugcgcc      540

accaccuccc ugaaccccga cuaccgcgag gaggacacgg ggcggccccg cgagagcggc      600

aagaagcgga agcgcaagcg ccucaagccg accuga                                636


<210>  293
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  293
augaaccgcu gcugggcccu guuccucagc cugugcugcu accugcggcu cguguccgcc       60

gagggcgacc ccaucccgga ggagcuguac gagaugcuga gcgaccacuc cauccgcagc      120

uucgacgacc uccagcggcu gcugcacggg gaccccggcg aggaggacgg ggcggagcuc      180

gaccugaaca ugacccgcuc ccacagcggc ggggagcugg agucccucgc ccggggccgc      240

cggagccugg gcucccugac caucgccgag cccgccauga ucgccgagug caagacgcgc      300

accgaggucu ucgagaucag ccggcgccuc aucgaccgga ccaacgcgaa cuuccuggug      360

uggcccccgu gcguggaggu ccagcgcugc uccgggugcu gcaacaaccg gaacgugcag      420

ugccgcccca cccaggugca gcugcggccc guccaggugc gcaagaucga gaucgugcgg      480

aagaagccca ucuucaagaa ggccacgguc acccucgagg accaccuggc cugcaagugc      540

gagaccgugg ccgcggcccg cccggugacc cggagccccg gcggguccca ggagcagcgc      600

gccaagacgc cccagacccg ggucaccauc cgcaccgugc gcgugcggcg gcccccgaag      660

ggcaagcacc gcaaguucaa gcacacgcac gacaagaccg cccugaagga gacccucggg      720

gccuga                                                                 726


<210>  294
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  294
augagccugu ucggccuccu gcugcucacc uccgcccugg ccgggcagcg ccagggcacc       60

caggcggaga gcaaccuguc cagcaaguuc caguucucca gcaacaagga gcagaacggg      120

gugcaggacc cccagcacga gcggaucauc acggucucca ccaacggcag cauccacucc      180

ccgcgcuucc cccacaccua cccccggaac accgugcucg uguggcgccu ggucgccgug      240

gaggagaacg uguggaucca gcugacguuc gacgagcggu ucgggcucga ggaccccgag      300

gacgacaucu gcaaguacga cuucgucgag guggaggagc cgagcgacgg caccauccug      360

ggccgcuggu gcggguccgg caccgugccc gggaagcaga ucagcaaggg caaccagauc      420

cggauccgcu ucgucuccga cgaguacuuc cccagcgagc ccggguucug cauccacuac      480

aacaucguga ugccgcaguu caccgaggcc guguccccca gcguccugcc gcccuccgcc      540

cucccccugg accugcucaa caacgccauc acggcguuca gcacccugga ggaccugauc      600

cgguaccucg agcccgagcg cuggcagcug gaccuggagg accucuaccg gcccaccugg      660

cagcugcugg gcaaggccuu cguguucggc cgcaaguccc ggguggucga ccucaaccug      720

cugaccgagg aggugcgccu cuacagcugc acgccccgga acuucagcgu guccauccgc      780

gaggagcuga agcggaccga caccaucuuc uggccggggu gccugcucgu caagcgcugc      840

ggcgggaacu gcgccugcug ccugcacaac ugcaacgagu gccagugcgu gcccagcaag      900

gugaccaaga aguaccacga gguccugcag cuccggccca agacgggcgu gcgcggccug      960

cacaaguccc ugaccgacgu ggcccucgag caccacgagg agugcgacug cgucugccgg     1020

gggagcaccg gcggguga                                                   1038


<210>  295
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  295
augcaccgcc ugaucuucgu guacacccuc aucugcgcca acuucugcag cugccgggac       60

accuccgcca cgccccagag cgcguccauc aaggcccugc gcaacgccaa ccugcggcgc      120

gacgaccucu accggcgcga cgagaccauc caggucaagg gcaacgggua cgugcagagc      180

ccccgguucc ccaacuccua cccccgcaac cugcugcuca ccuggcggcu gcacagccag      240

gagaacaccc gcauccagcu gguguucgac aaccaguucg gccucgagga ggccgagaac      300

gacaucugcc gguacgacuu cgucgaggug gaggacaucu ccgagaccag caccaucauc      360

cgcgggcggu ggugcggcca caaggaggug cccccgcgca ucaagucccg gaccaaccag      420

aucaagauca ccuucaagag cgacgacuac uucgucgcca agcccggguu caagaucuac      480

uacucccugc uggaggacuu ccagcccgcg gccgccagcg agacgaacug ggaguccgug      540

accagcucca ucagcggcgu guccuacaac agccccuccg ucaccgaccc gacccucauc      600

gccgacgcgc uggacaagaa gaucgccgag uucgacacgg uggaggaccu gcucaaguac      660

uucaaccccg agagcuggca ggaggaccug gagaacaugu accuggacac cccgcgcuac      720

cggggccgca gcuaccacga ccggaagucc aagguggacc ucgaccgccu gaacgacgac      780

gccaagcggu acagcugcac gccccgcaac uacuccguca acauccgcga ggagcugaag      840

cucgccaacg ugguguucuu cccccggugc cugcuggucc agcgcugcgg gggcaacugc      900

gggugcggca ccgugaacug gcggagcugc acgugcaacu ccgggaagac cgugaagaag      960

uaccacgagg uccuccaguu cgagcccggc cacaucaagc gccggggccg cgccaagacc     1020

auggcgcugg uggacaucca gcuggaccac cacgagcggu gcgacugcau cugcagcucc     1080

cgcccgcccc gguga                                                      1095


<210>  296
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  296
auggugaccc acagcaaguu ccccgccgcc ggcauguccc gcccgcugga caccagccuc       60

cggcugaaga cguucuccag caaguccgag uaccagcugg ucgugaacgc ggugcgcaag      120

cuccaggaga gcggguucua cugguccgcc gucaccggcg gggaggccaa ccugcugcuc      180

agcgccgagc ccgccggcac cuuccugauc cgggacucca gcgaccagcg ccacuucuuc      240

acccuguccg ugaagacgca gagcgggacc aagaaccucc ggauccagug cgagggcggc      300

uccuucagcc ugcaguccga cccccgcagc acccagcccg ugccgcgguu cgacugcguc      360

cugaagcucg ugcaccacua caugcccccg cccggggcgc ccuccuuccc cagcccgccc      420

accgagcccu ccagcgaggu gcccgagcag cccagcgccc agccccugcc gggcuccccg      480

ccccgccggg ccuacuacau cuacagcggg ggcgagaaga ucccccuggu ccucucccgc      540

ccccugagcu ccaacguggc cacgcugcag caccucugcc ggaagaccgu gaacgggcac      600

cuggacagcu acgagaaggu cacccagcug cccggcccca uccgcgaguu ccucgaccag      660

uacgacgcgc cccuguga                                                    678


<210>  297
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  297
auggugccca gcgccggcca gcuggcccuc uucgcgcugg ggaucguccu ggccgccugc       60

caggcccucg agaacuccac cagcccgcug uccgccgacc cgcccguggc ggccgccgug      120

gucagccacu ucaacgacug ccccgacucc cacacccagu ucugcuucca cggcacgugc      180

cgcuuccugg ugcaggagga caagcccgcc ugcgugugcc acagcgggua cgucggcgcg      240

cggugcgagc acgccgaccu ccuggccgug guggccgccu cccagaagaa gcaggcgauc      300

accgcccugg ucguggugag caucgucgcc cucgccgugc ugaucaucac gugcgugcug      360

auccacugcu gccagguccg caagcacugc gaguggugcc gggcccucau cugccgccac      420

gagaagcccu ccgcgcugcu gaaggggcgg accgccugcu gccacagcga gaccguggug      480

uga                                                                    483


<210>  298
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  298
augcccccga gcggccugcg ccuccugccc cugcuccugc cccugcucug gcugcuggug       60

cucacccccg ggcggccggc cgccggccug uccacgugca agaccaucga cauggagcug      120

gucaagcgca agcggaucga ggcgauccgc gggcagaucc ucagcaagcu gcggcuggcc      180

uccccgccca gccagggcga ggugccgccc gggccccucc ccgaggccgu gcuggcccug      240

uacaacucca cccgcgaccg ggucgccggc gagagcgcgg agcccgagcc cgagcccgag      300

gccgacuacu acgccaagga ggugacccgc gugcucaugg ucgagaccca caacgagauc      360

uacgacaagu ucaagcaguc cacgcacagc aucuacaugu ucuucaacac cuccgagcug      420

cgggaggccg ugcccgagcc cgugcugcuc agccgcgcgg agcugcggcu gcuccgccug      480

aagcugaagg ucgagcagca cguggagcuc uaccagaagu acuccaacaa cagcuggcgg      540

uaccugucca accgccugcu cgccccgagc gacucccccg aguggcugag cuucgacgug      600

accggcgucg ugcggcagug gcugucccgc gggggcgaga ucgagggguu ccggcucagc      660

gcccacugcu ccugcgacag ccgcgacaac acccuccagg uggacaucaa cggcuucacg      720

accgggcggc gcggcgaccu ggccaccauc cacggcauga accggcccuu ccugcugcug      780

auggccacgc cccucgagcg cgcgcagcac cuccagagcu cccgccaccg gcgcgcccug      840

gacaccaacu acugcuucag cuccaccgag aagaacugcu gcguccggca gcuguacauc      900

gacuuccgca aggaccuggg guggaagugg auccacgagc cgaagggcua ccacgccaac      960

uucugccugg ggcccugccc cuacaucugg agccucgaca cccaguacuc caaggugcug     1020

gcccuguaca accagcacaa ccccggcgcc agcgcggccc cgugcugcgu gccccaggcc     1080

cucgagcccc ugcccaucgu cuacuacgug ggccggaagc cgaaggugga gcagcugucc     1140

aacaugaucg uccgcagcug caagugcucc uga                                  1173


<210>  299
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  299
augcacuacu gcgugcugag cgccuuccuc auccugcacc uggucaccgu ggcccucucc       60

cugagcacgu gcuccacccu ggacauggac caguucaugc gcaagcggau cgaggcgauc      120

cgcggccaga uccucagcaa gcugaagcug accagcccgc ccgaggacua ccccgagccc      180

gaggaggugc ccccggaggu caucuccauc uacaacucca cccgggaccu ccugcaggag      240

aaggccagcc gccgggccgc cgccugcgag cgcgagcggu ccgacgagga guacuacgcg      300

aaggaggugu acaagaucga caugccgccc uucuucccca gcgagaacgc caucccgccc      360

accuucuacc gccccuacuu ccggaucgug cgcuucgacg ucuccgccau ggagaagaac      420

gccagcaacc uggugaaggc ggaguuccgg guguuccgcc uccagaaccc caaggcccgg      480

guccccgagc agcgcaucga gcuguaccag auccugaagu ccaaggaccu cacgagcccc      540

acccagcggu acaucgacuc caagguggug aagacccgcg ccgaggggga guggcugagc      600

uucgacguca ccgacgccgu gcacgagugg cugcaccaca aggaccggaa ccucggcuuc      660

aagaucuccc ugcacugccc cugcugcacg uucgugccca gcaacaacua caucaucccg      720

aacaaguccg aggagcugga ggcccgcuuc gcggggaucg acggcaccag caccuacacc      780

agcggggacc agaagacgau caaguccacc cggaagaaga acagcggcaa gacgccccac      840

cuccugcuga ugcuccugcc cuccuaccgc cuggagagcc agcagaccaa ccggcgcaag      900

aagcgcgccc ucgacgccgc cuacugcuuc cggaacgucc aggacaacug cugccugcgc      960

ccccuguaca ucgacuucaa gcgggaccuc ggcuggaagu ggauccacga gccgaagggg     1020

uacaacgcca acuucugcgc gggcgccugc cccuaccugu gguccagcga cacccagcac     1080

ucccgcgugc ugagccucua caacaccauc aaccccgagg ccuccgccag ccccugcugc     1140

gugucccagg accuggagcc gcugaccauc cucuacuaca ucgggaagac ccccaagauc     1200

gagcagcuga gcaacaugau cgucaagucc ugcaagugca gcuga                     1245


<210>  300
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  300
augaagaugc accuccagcg cgcccucgug gugcuggccc ugcucaacuu cgcgaccgug       60

agccuguccc ugagcacgug caccacccuc gacuucggcc acaucaagaa gaagcgggug      120

gaggccaucc gcgggcagau ccuguccaag cugcggcuca ccagcccgcc cgagcccacc      180

gucaugacgc acgugcccua ccaggugcug gcccuguaca acuccacccg cgagcuccug      240

gaggagaugc acggcgagcg ggaggagggg ugcacccagg agaacaccga gagcgaguac      300

uacgccaagg agauccacaa guucgacaug auccagggcc uggccgagca caacgagcuc      360

gcggucugcc ccaaggggau cacguccaag guguuccgcu ucaacgugag cuccgucgag      420

aagaaccgga ccaaccuguu ccgcgccgag uuccgggugc ugcgcgugcc gaaccccagc      480

uccaagcgga acgagcagcg caucgagcug uuccagaucc ugcggcccga cgagcacauc      540

gccaagcagc gcuacaucgg cggcaagaac cugcccaccc gggggaccgc cgaguggcuc      600

agcuucgacg ucacggacac cgugcgcgag uggcugcugc ggcgcgaguc caaccucggc      660

cuggagauca gcauccacug cccgugccac accuuccagc ccaacgggga cauccuggag      720

aacauccacg aggugaugga gaucaaguuc aagggcgucg acaacgagga cgaccacggg      780

cggggcgacc ucggccgccu gaagaagcag aaggaccacc acaaccccca ccugauccuc      840

augaugaucc cgccccaccg gcuggacaac cccgggcagg gcgggcagcg caagaagcgc      900

gcgcuggaca ccaacuacug cuuccggaac cucgaggaga acugcugcgu gcgcccccug      960

uacaucgacu uccggcagga ccugggcugg aagugggugc acgagcccaa gggcuacuac     1020

gccaacuucu gcuccgggcc gugccccuac cuccgcagcg ccgacacgac ccacuccacc     1080

guccugggcc uguacaacac ccucaacccc gaggccagcg ccucccccug cugcgugccg     1140

caggaccugg agccccugac gauccucuac uacguggggc ggacccccaa ggucgagcag     1200

cugagcaaca ugguggucaa gagcugcaag ugcuccuga                            1239


<210>  301
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  301
auggcccccg uggccgucug ggcggcccug gccgugggcc ucgagcugug ggccgccgcg       60

cacgcccugc cggcccaggu ggccuucacc cccuacgcgc ccgagcccgg gagcacgugc      120

cgccuccggg aguacuacga ccagaccgcc cagaugugcu gcuccaagug cagcccgggc      180

cagcacgcca aggucuucug caccaagacc uccgacaccg ugugcgacag cugcgaggac      240

uccacguaca cccagcugug gaacugggug cccgagugcc ugagcugcgg gucccgcugc      300

agcuccgacc aggucgagac ccaggccugc acccgggagc agaaccgcau cugcacgugc      360

cggcccggcu gguacugcgc ccucagcaag caggaggggu gccgccugug cgcgccccug      420

cggaagugcc gcccgggcuu cggcguggcc cggcccggga ccgagaccuc cgacgugguc      480

ugcaagcccu gcgcccccgg caccuucagc aacacgaccu ccagcaccga caucugccgc      540

ccgcaccaga ucugcaacgu gguggccauc cccgggaacg ccuccaugga cgcggucugc      600

accagcacgu cccccacccg gagcauggcc cccggcgccg ugcaccuccc gcagcccgug      660

uccacccgca gccagcacac ccagcccacg cccgagccga gcaccgcccc cuccaccagc      720

uuccugcugc ccauggggcc cuccccgccc gccgagggca gcaccggcga cuucgcgcuc      780

cccgucgggc ugaucguggg cgugacggcc cuggggcucc ugaucaucgg cgucgugaac      840

ugcgugauca ugacccaggu caagaagaag ccccugugcc uccagcggga ggccaaggug      900

ccgcaccucc ccgccgacaa ggcccgcggc acccaggggc ccgagcagca gcaccuccug      960

aucaccgcgc cguccagcuc cagcuccagc cuggagucca gcgccuccgc ccuggaccgg     1020

cgcgccccca cgcggaacca gccccaggcg cccggcgugg aggccagcgg ggccggcgag     1080

gcccgcgccu ccaccgggag cuccgacagc uccccgggcg gccacgggac ccaggucaac     1140

gugaccugca ucgucaacgu gugcagcagc uccgaccaca gcucccagug cagcucccag     1200

gcgagcucca cgaugggcga caccgacagc ucccccagcg agucccccaa ggacgagcag     1260

guccccuuca gcaaggagga gugcgccuuc cggucccagc uggagacccc ggagacccug     1320

cuggggagca cggaggagaa gccccucccc cugggcgugc ccgacgccgg gaugaagccg     1380

uccuga                                                                1386


<210>  302
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  302
augcccguga ugcgccuguu cccgugcuuc cuccagcugc uggccggccu cgcccugccc       60

gcggucccgc cccagcagug ggcccugagc gccgggaacg gcuccagcga gguggaggug      120

guccccuucc aggaggugug ggggcggucc uacugccgcg cccucgagcg gcugguggac      180

gucgugagcg aguaccccuc cgagguggag cacauguuca gccccuccug cgucagccug      240

cuccgcugca ccggcugcug cggggacgag aaccugcacu gcgugcccgu ggagaccgcc      300

aacgucacga ugcagcugcu caagauccgg uccggcgacc gcccgagcua cguggagcug      360

accuucuccc agcacgugcg gugcgagugc cgcccccugc gggagaagau gaagcccgag      420

cgccggcgcc ccaagggccg ggggaagcgc cggcgcgaga agcagcggcc gaccgacugc      480

caccucugcg gcgacgcggu cccccgccgg uga                                   513


<210>  303
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  303
augaccgacc gccagaccga cacggccccc agcccguccu accaccuccu gcccggccgg       60

cgccggaccg uggacgccgc ggccagccgc gggcagggcc ccgagcccgc ccccgggggc      120

ggggucgagg gcgugggcgc ccgcggggug gcccugaagc uguucgucca gcuccugggc      180

ugcucccggu ucgggggcgc gguggugcgg gccggggagg ccgagcccag cggcgccgcg      240

cgcuccgcca gcuccggccg ggaggagccc cagcccgagg agggggagga ggaggaggag      300

aaggaggagg agcgcggccc gcaguggcgg cugggggccc gcaagcccgg cagcuggacc      360

ggcgaggccg ccgucugcgc ggacuccgcc cccgccgccc gggccccgca ggcgcucgcc      420

cgcgccagcg ggcggggcgg gcgcguggcc cggcgcggcg ccgaggaguc cgggccgccc      480

cacagccccu cccggcgcgg cagcgcgucc cgggccggcc ccgggcgcgc cagcgagacc      540

augaacuucc ugcuguccug ggugcacugg agccucgccc ugcugcucua ccugcaccac      600

gccaaguggu cccaggcggc cccgauggcc gagggcgggg gccagaacca ccacgagguc      660

gugaaguuca uggacgugua ccagcgcagc uacugccacc ccaucgagac gcuggucgac      720

aucuuccagg aguaccccga cgagaucgag uacaucuuca agcccagcug cgugccgcuc      780

augcggugcg ggggcugcug caacgacgag ggccuggagu gcgugcccac cgaggagucc      840

aacaucacca ugcagaucau gcgcaucaag ccccaccagg ggcagcacau cggcgagaug      900

agcuuccugc agcacaacaa gugcgagugc cggcccaaga aggaccgcgc ccggcaggag      960

aagaaguccg uccgcgggaa gggcaagggg cagaagcgga agcgcaagaa gucccgguac     1020

aagagcugga gcguguacgu gggcgcgcgc ugcugccuca ugccgugguc ccugcccggc     1080

ccccaccccu gcgggccgug cagcgagcgg cgcaagcacc uguucgucca ggacccccag     1140

accugcaagu gcuccugcaa gaacacggac agccggugca aggcccgcca gcucgagcug     1200

aacgagcgga ccugccgcug cgacaagccc cggcgcuga                            1239


<210>  304
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  304
augaacuucc ugcucagcug ggugcacugg ucccuggccc ugcuccugua ccugcaccac       60

gccaagugga gccaggcggc ccccauggcc gagggcgggg gccagaacca ccacgagguc      120

gugaaguuca uggacgugua ccagcgcucc uacugccacc cgaucgagac ccucgucgac      180

aucuuccagg aguaccccga cgagaucgag uacaucuuca agcccagcug cgugccccug      240

augcggugcg ggggcugcug caacgacgag gggcuggagu gcgugccgac cgaggagucc      300

aacaucacga ugcagaucau gcgcaucaag ccccaccagg gccagcacau cggcgagaug      360

agcuuccucc agcacaacaa gugcgagugc cggcccaaga aggaccgcgc ccggcaggag      420

aagaaguccg uccgcgggaa gggcaagggg cagaagcgga agcgcaagaa gucccgguac      480

aagagcugga gcguguacgu gggcgcccgc ugcugccuga ugcccugguc ccugccgggg      540

ccccaccccu gcggccccug cagcgagcgg cgcaagcacc ucuucgucca ggacccgcag      600

accugcaagu gcuccugcaa gaacaccgac agccggugca aggcgcgcca gcuggagcug      660

aacgagcgga ccugccgcug cgacaagccc cggcgcuga                             699


<210>  305
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  305
augagccccc ugcuccgccg gcugcugcuc gccgcccugc ugcagcucgc gccggcccag       60

gcccccgugu cccagcccga cgcccccggc caccagcgca aggucgugag cuggaucgac      120

guguacaccc gggcgaccug ccagccgcgc gaggucgugg ugccccugac ggucgagcug      180

auggggaccg uggccaagca gcucgugccc uccugcguca ccgugcagcg gugcggcggg      240

ugcugccccg acgacggccu ggagugcgug ccgaccgggc agcaccaggu ccgcaugcag      300

auccugauga uccgguaccc cagcucccag cucggcgaga ugagccugga ggagcacucc      360

cagugcgagu gccgccccaa gaagaaggac agcgccguga agcccgaccg ggccgccacg      420

ccgcaccacc gcccccagcc ccgguccgug cccggcuggg acagcgcgcc gggggccccc      480

ucccccgccg acaucaccca ccccaccccg gcccccggcc ccagcgccca cgcggccccc      540

uccaccacga gcgcccugac cccggggccc gccgccgcgg ccgccgacgc cgccgcgucc      600

agcgucgcca agggcggggc cuga                                             624


<210>  306
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  306
augcaccucc ugggcuucuu cagcguggcc ugcucccugc uggccgcggc ccuccugccc       60

gggccgcgcg aggcccccgc cgccgcggcc gccuucgaga gcggccugga ccucuccgac      120

gccgagcccg acgcggggga ggccaccgcc uacgccagca aggaccugga ggagcagcug      180

cgguccguca gcuccgugga cgagcucaug accgugcugu accccgagua cuggaagaug      240

uacaagugcc agcugcgcaa gggcgggugg cagcacaacc gggagcaggc caaccucaac      300

agccgcacgg aggagaccau caaguucgcg gccgcccacu acaacaccga gauccugaag      360

uccaucgaca acgaguggcg gaagacccag ugcaugccgc gcgaggucug caucgacgug      420

ggcaaggagu ucggcguggc cacgaacacc uucuucaagc cgcccugcgu cagcguguac      480

cggugcgggg gcugcugcaa cuccgagggg cugcagugca ugaacaccag caccuccuac      540

cucagcaaga cgcuguucga gaucaccgug ccccuguccc agggccccaa gcccgucacc      600

aucagcuucg ccaaccacac cuccugccgc ugcaugagca agcucgacgu guaccgccag      660

gugcacucca ucauccggcg gagccugccc gcgacgcugc cccagugcca ggccgccaac      720

aagaccugcc cgaccaacua cauguggaac aaccacaucu gccgcugccu cgcccaggag      780

gacuucaugu ucagcuccga cgccggggac gacagcaccg acggcuucca cgacaucugc      840

ggccccaaca aggagcugga cgaggagacg ugccagugcg ucugccgggc ggggcugcgc      900

cccgccuccu gcggccccca caaggagcuc gaccggaaca gcugccagug cgugugcaag      960

aacaagcugu ucccguccca gugcggggcc aaccgcgagu ucgacgagaa cacgugccag     1020

ugcgugugca agcggaccug cccccgcaac cagccccuga accccggcaa gugcgccugc     1080

gagugcaccg agagcccgca gaagugccuc cugaagggca agaaguucca ccaccagacc     1140

ugcuccugcu accggcgccc cugcaccaac cggcagaagg ccugcgagcc cggguucagc     1200

uacuccgagg aggucugccg cugcgugccc agcuacugga agcgcccgca gauguccuga     1260


<210>  307
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  307
auguaccgcg aguggguggu cgugaacgug uucaugaugc uguacgucca gcucgugcag       60

ggcagcucca acgagcacgg gcccgugaag cggagcuccc agagcacccu ggagcgcucc      120

gagcagcaga uccgggccgc cagcucccug gaggagcucc ugcgcaucac ccacagcgag      180

gacuggaagc uguggcggug ccgccuccgg cugaaguccu ucacgagcau ggacucccgc      240

agcgcguccc accggagcac ccgcuucgcc gccaccuucu acgacaucga gacccugaag      300

gucaucgacg aggaguggca gcggacgcag ugcuccccgc gcgagaccug cguggaggug      360

gccagcgagc ucggcaaguc caccaacacc uucuucaagc cgcccugcgu caacguguuc      420

cggugcgggg gcugcugcaa cgaggagagc cugaucugca ugaacacguc caccagcuac      480

aucagcaagc agcuguucga gaucuccgug ccccucacca gcguccccga gcuggugccc      540

gugaaggucg ccaaccacac cgggugcaag ugccugccca cggcgccccg ccacccguac      600

uccaucaucc ggcgcagcau ccagaucccc gaggaggacc ggugcuccca cagcaagaag      660

cucugcccca ucgacaugcu gugggacucc aacaagugca agugcgugcu gcaggaggag      720

aacccccucg ccggcaccga ggaccacagc caccuccagg agccggcccu gugcggcccc      780

cacaugaugu ucgacgagga ccgcugcgag ugcgugugca agacccccug ccccaaggac      840

cugauccagc acccgaagaa cugcuccugc uucgagugca aggagagccu ggagaccugc      900

ugccagaagc acaagcuguu ccaccccgac acgugcuccu gcgaggaccg gugccccuuc      960

cacacccgcc ccugcgccag cgggaagacc gcgugcgcca agcacugccg guucccgaag     1020

gagaagcgcg ccgcccaggg cccccacucc cgcaagaacc ccuga                     1065


<210>  308
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  308
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

cagaccuggg cc                                                           72


<210>  309
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  309
auggacgcca ugaagcgcgg ccucugcugc guccuccucc ucugcggcgc cgucuucguc       60

ucccccucc                                                               69


<210>  310
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  310
augggcgucc acgagugccc cgccuggcuc uggcuccucc ucucccuccu cucccucccc       60

cucggccucc ccguccucgg c                                                 81


<210>  311
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  311
augaaguggg ucaccuucau cucccuccuc uuccucuucu ccuccgccua cucc             54


<210>  312
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from 
       Artificial____cleavage site-Furin

<400>  312
cgccgccgcc gcaagcgc                                                     18


<210>  313
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  313
auggacuccg acgagaccgg cuucgagcac uccggccucu gggucuccgu ccucgccggc       60

cuccuccucg gcgccugcca ggcccacccc auccccgacu ccuccccccu ccuccaguuc      120

ggcggccagg uccgccagcg cuaccucuac accgacgacg cccagcagac cgaggcccac      180

cucgagaucc gcgaggacgg caccgucggc ggcgccgccg accagucccc cgagucccuc      240

cuccagcuca aggcccucaa gcccggcguc auccagaucc ucggcgucaa gaccucccgc      300

uuccucugcc agcgccccga cggcgcccuc uacggcuccc uccacuucga ccccgaggcc      360

ugcuccuucc gcgagcuccu ccucgaggac ggcuacaacg ucuaccaguc cgaggcccac      420

ggccuccccc uccaccuccc cggcaacaag uccccccacc gcgaccccgc cccccgcggc      480

cccgcccgcu uccucccccu ccccggccuc ccccccgccc uccccgagcc ccccggcauc      540

cucgcccccc agccccccga cgucggcucc uccgaccccc ucuccauggu cggccccucc      600

cagggccgcu cccccuccua cgccuccuga                                       630


<210>  314
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  314
augcacuccu uccccccccu ccuccuccuc cucuucuggg gcgucgucuc ccacuccuuc       60

cccgccaccc ucgagaccca ggagcaggac gucgaccucg uccagaagua ccucgagaag      120

uacuacaacc ucaagaacga cggccgccag gucgagaagc gccgcaacuc cggccccguc      180

gucgagaagc ucaagcagau gcaggaguuc uucggccuca aggucaccgg caagcccgac      240

gccgagaccc ucaaggucau gaagcagccc cgcugcggcg uccccgacgu cgcccaguuc      300

guccucaccg agggcaaccc ccgcugggag cagacccacc ucaccuaccg caucgagaac      360

uacacccccg accucccccg cgccgacguc gaccacgcca ucgagaaggc cuuccagcuc      420

ugguccaacg ucaccccccu caccuucacc aaggucuccg agggccaggc cgacaucaug      480

aucuccuucg uccgcggcga ccaccgcgac aacucccccu ucgacggccc cggcggcaac      540

cucgcccacg ccuuccagcc cggccccggc aucggcggcg acgcccacuu cgacgaggac      600

gagcgcugga ccaacaacuu ccgcgaguac aaccuccacc gcgucgccgc ccacgagcuc      660

ggccacuccc ucggccucuc ccacuccacc gacaucggcg cccucaugua ccccuccuac      720

accuucuccg gcgacgucca gcucgcccag gacgacaucg acggcaucca ggccaucuac      780

ggccgcuccc agaaccccgu ccagcccauc ggcccccaga cccccaaggc cugcgacucc      840

aagcucaccu ucgacgccau caccaccauc cgcggcgagg ucauguucuu caaggaccgc      900

uucuacaugc gcaccaaccc cuucuacccc gaggucgagc ucaacuucau cuccgucuuc      960

uggccccagc uccccaacgg ccucgaggcc gccuacgagu ucgccgaccg cgacgagguc     1020

cgcuucuuca agggcaacaa guacugggcc guccagggcc agaacguccu ccacggcuac     1080

cccaaggaca ucuacuccuc cuucggcuuc ccccgcaccg ucaagcacau cgacgccgcc     1140

cucuccgagg agaacaccgg caagaccuac uucuucgucg ccaacaagua cuggcgcuac     1200

gacgaguaca agcgcuccau ggaccccggc uaccccaaga ugaucgccca cgacuucccc     1260

ggcaucggcc acaaggucga cgccgucuuc augaaggacg gcuucuucua cuucuuccac     1320

ggcacccgcc aguacaaguu cgaccccaag accaagcgca uccucacccu ccagaaggcc     1380

aacuccuggu ucaacugccg caagaacuga                                      1410


<210>  315
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  315
augcacuccu uccccccccu ccuccuccuc cucuucuggg gcgucgucuc ccacuccuuc       60

guccucaccg agggcaaccc ccgcugggag cagacccacc ucaccuaccg caucgagaac      120

uacacccccg accucccccg cgccgacguc gaccacgcca ucgagaaggc cuuccagcuc      180

ugguccaacg ucaccccccu caccuucacc aaggucuccg agggccaggc cgacaucaug      240

aucuccuucg uccgcggcga ccaccgcgac aacucccccu ucgacggccc cggcggcaac      300

cucgcccacg ccuuccagcc cggccccggc aucggcggcg acgcccacuu cgacgaggac      360

gagcgcugga ccaacaacuu ccgcgaguac aaccuccacc gcgucgccgc ccacgagcuc      420

ggccacuccc ucggccucuc ccacuccacc gacaucggcg cccucaugua ccccuccuac      480

accuucuccg gcgacgucca gcucgcccag gacgacaucg acggcaucca ggccaucuac      540

ggccgcuccc agaaccccgu ccagcccauc ggcccccaga cccccaaggc cugcgacucc      600

aagcucaccu ucgacgccau caccaccauc cgcggcgagg ucauguucuu caaggaccgc      660

uucuacaugc gcaccaaccc cuucuacccc gaggucgagc ucaacuucau cuccgucuuc      720

uggccccagc uccccaacgg ccucgaggcc gccuacgagu ucgccgaccg cgacgagguc      780

cgcuucuuca agggcaacaa guacugggcc guccagggcc agaacguccu ccacggcuac      840

cccaaggaca ucuacuccuc cuucggcuuc ccccgcaccg ucaagcacau cgacgccgcc      900

cucuccgagg agaacaccgg caagaccuac uucuucgucg ccaacaagua cuggcgcuac      960

gacgaguaca agcgcuccau ggaccccggc uaccccaaga ugaucgccca cgacuucccc     1020

ggcaucggcc acaaggucga cgccgucuuc augaaggacg gcuucuucua cuucuuccac     1080

ggcacccgcc aguacaaguu cgaccccaag accaagcgca uccucacccu ccagaaggcc     1140

aacuccuggu ucaacugccg caagaacuga                                      1170


<210>  316
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  316
augaagaaga acauccucaa gauccucaug gacuccuacu ccaaggaguc caagauccag       60

accguccgcc gcgucaccuc cgucucccuc cucgccgucu accucaccau gaacaccucc      120

ucccucgucc ucgccaagcc caucgagaac accaacgaca ccuccaucaa gaacgucgag      180

aagcuccgca acgcccccaa cgaggagaac uccaagaagg ucgaggacuc caagaacgac      240

aaggucgagc acgucaagaa caucgaggag gccaaggucg agcaggucgc ccccgagguc      300

aaguccaagu ccacccuccg cuccgccucc aucgccaaca ccaacuccga gaaguacgac      360

uucgaguacc ucaacggccu cuccuacacc gagcucacca accucaucaa gaacaucaag      420

uggaaccaga ucaacggccu cuucaacuac uccaccggcu cccagaaguu cuucggcgac      480

aagaaccgcg uccaggccau caucaacgcc cuccaggagu ccggccgcac cuacaccgcc      540

aacgacauga agggcaucga gaccuucacc gagguccucc gcgccggcuu cuaccucggc      600

uacuacaacg acggccucuc cuaccucaac gaccgcaacu uccaggacaa gugcaucccc      660

gccaugaucg ccauccagaa gaaccccaac uucaagcucg gcaccgccgu ccaggacgag      720

gucaucaccu cccucggcaa gcucaucggc aacgccuccg ccaacgccga ggucgucaac      780

aacugcgucc ccguccucaa gcaguuccgc gagaaccuca accaguacgc ccccgacuac      840

gucaagggca ccgccgucaa cgagcucauc aagggcaucg aguucgacuu cuccggcgcc      900

gccuacgaga aggacgucaa gaccaugccc ugguacggca agaucgaccc cuucaucaac      960

gagcucaagg cccucggccu cuacggcaac aucaccuccg ccaccgagug ggccuccgac     1020

gucggcaucu acuaccucuc caaguucggc cucuacucca ccaaccgcaa cgacaucguc     1080

cagucccucg agaaggccgu cgacauguac aaguacggca agaucgccuu cgucgccaug     1140

gagcgcauca ccugggacua cgacggcauc ggcuccaacg gcaagaaggu cgaccacgac     1200

aaguuccucg acgacgccga gaagcacuac cuccccaaga ccuacaccuu cgacaacggc     1260

accuucauca uccgcgccgg cgacaagguc uccgaggaga agaucaagcg ccucuacugg     1320

gccucccgcg aggucaaguc ccaguuccac cgcgucgucg gcaacgacaa ggcccucgag     1380

gucggcaacg ccgacgacgu ccucaccaug aagaucuuca acucccccga ggaguacaag     1440

uucaacacca acaucaacgg cgucuccacc gacaacggcg gccucuacau cgagccccgc     1500

ggcaccuucu acaccuacga gcgcaccccc cagcagucca ucuucucccu cgaggagcuc     1560

uuccgccacg aguacaccca cuaccuccag gcccgcuacc ucgucgacgg ccucuggggc     1620

cagggccccu ucuacgagaa gaaccgccuc accugguucg acgagggcac cgccgaguuc     1680

uucgccggcu ccacccgcac cuccggcguc cucccccgca aguccauccu cggcuaccuc     1740

gccaaggaca aggucgacca ccgcuacucc cucaagaaga cccucaacuc cggcuacgac     1800

gacuccgacu ggauguucua caacuacggc uucgccgucg cccacuaccu cuacgagaag     1860

gacaugccca ccuucaucaa gaugaacaag gccauccuca acaccgacgu caaguccuac     1920

gacgagauca ucaagaagcu cuccgacgac gccaacaaga acaccgagua ccagaaccac     1980

auccaggagc ucgccgacaa guaccagggc gccggcaucc cccucgucuc cgacgacuac     2040

cucaaggacc acggcuacaa gaaggccucc gaggucuacu ccgagaucuc caaggccgcc     2100

ucccucacca acaccuccgu caccgccgag aagucccagu acuucaacac cuucacccuc     2160

cgcggcaccu acaccggcga gaccuccaag ggcgaguuca aggacuggga cgagaugucc     2220

aagaagcucg acggcacccu cgagucccuc gccaagaacu ccugguccgg cuacaagacc     2280

cucaccgccu acuucaccaa cuaccgcguc accuccgaca acaaggucca guacgacguc     2340

gucuuccacg gcguccucac cgacaacgcc gacaucucca acaacaaggc ccccaucgcc     2400

aaggucaccg gccccuccac cggcgccguc ggccgcaaca ucgaguucuc cggcaaggac     2460

uccaaggacg aggacggcaa gaucgucucc uacgacuggg acuucggcga cggcgccacc     2520

ucccgcggca agaacuccgu ccacgccuac aagaaggccg gcaccuacaa cgucacccuc     2580

aaggucaccg acgacaaggg cgccaccgcc accgaguccu ucaccaucga gaucaagaac     2640

gaggacacca ccacccccau caccaaggag auggagccca acgacgacau caaggaggcc     2700

aacggcccca ucgucgaggg cgucaccguc aagggcgacc ucaacggcuc cgacgacgcc     2760

gacaccuucu acuucgacgu caaggaggac ggcgacguca ccaucgagcu ccccuacucc     2820

ggcuccucca acuucaccug gcucgucuac aaggagggcg acgaccagaa ccacaucgcc     2880

uccggcaucg acaagaacaa cuccaagguc ggcaccuuca aguccaccaa gggccgccac     2940

uacgucuuca ucuacaagca cgacuccgcc uccaacaucu ccuacucccu caacaucaag     3000

ggccucggca acgagaagcu caaggagaag gagaacaacg acuccuccga caaggccacc     3060

gucaucccca acuucaacac caccaugcag ggcucccucc ucggcgacga cucccgcgac     3120

uacuacuccu ucgaggucaa ggaggagggc gaggucaaca ucgagcucga caagaaggac     3180

gaguucggcg ucaccuggac ccuccacccc gaguccaaca ucaacgaccg caucaccuac     3240

ggccaggucg acggcaacaa ggucuccaac aaggucaagc uccgccccgg caaguacuac     3300

cuccucgucu acaaguacuc cggcuccggc aacuacgagc uccgcgucaa caaguga        3357


<210>  317
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  317
augaaguggg ucaccuucau cucccuccuc uuccucuucu ccuccgccua cuccaucgcc       60

aacaccaacu ccgagaagua cgacuucgag uaccucaacg gccucuccua caccgagcuc      120

accaaccuca ucaagaacau caaguggaac cagaucaacg gccucuucaa cuacuccacc      180

ggcucccaga aguucuucgg cgacaagaac cgcguccagg ccaucaucaa cgcccuccag      240

gaguccggcc gcaccuacac cgccaacgac augaagggca ucgagaccuu caccgagguc      300

cuccgcgccg gcuucuaccu cggcuacuac aacgacggcc ucuccuaccu caacgaccgc      360

aacuuccagg acaagugcau ccccgccaug aucgccaucc agaagaaccc caacuucaag      420

cucggcaccg ccguccagga cgaggucauc accucccucg gcaagcucau cggcaacgcc      480

uccgccaacg ccgaggucgu caacaacugc guccccgucc ucaagcaguu ccgcgagaac      540

cucaaccagu acgcccccga cuacgucaag ggcaccgccg ucaacgagcu caucaagggc      600

aucgaguucg acuucuccgg cgccgccuac gagaaggacg ucaagaccau gcccugguac      660

ggcaagaucg accccuucau caacgagcuc aaggcccucg gccucuacgg caacaucacc      720

uccgccaccg agugggccuc cgacgucggc aucuacuacc ucuccaaguu cggccucuac      780

uccaccaacc gcaacgacau cguccagucc cucgagaagg ccgucgacau guacaaguac      840

ggcaagaucg ccuucgucgc cauggagcgc aucaccuggg acuacgacgg caucggcucc      900

aacggcaaga aggucgacca cgacaaguuc cucgacgacg ccgagaagca cuaccucccc      960

aagaccuaca ccuucgacaa cggcaccuuc aucauccgcg ccggcgacaa ggucuccgag     1020

gagaagauca agcgccucua cugggccucc cgcgagguca agucccaguu ccaccgcguc     1080

gucggcaacg acaaggcccu cgaggucggc aacgccgacg acguccucac caugaagauc     1140

uucaacuccc ccgaggagua caaguucaac accaacauca acggcgucuc caccgacaac     1200

ggcggccucu acaucgagcc ccgcggcacc uucuacaccu acgagcgcac cccccagcag     1260

uccaucuucu cccucgagga gcucuuccgc cacgaguaca cccacuaccu ccaggcccgc     1320

uaccucgucg acggccucug gggccagggc cccuucuacg agaagaaccg ccucaccugg     1380

uucgacgagg gcaccgccga guucuucgcc ggcuccaccc gcaccuccgg cguccucccc     1440

cgcaagucca uccucggcua ccucgccaag gacaaggucg accaccgcua cucccucaag     1500

aagacccuca acuccggcua cgacgacucc gacuggaugu ucuacaacua cggcuucgcc     1560

gucgcccacu accucuacga gaaggacaug cccaccuuca ucaagaugaa caaggccauc     1620

cucaacaccg acgucaaguc cuacgacgag aucaucaaga agcucuccga cgacgccaac     1680

aagaacaccg aguaccagaa ccacauccag gagcucgccg acaaguacca gggcgccggc     1740

aucccccucg ucuccgacga cuaccucaag gaccacggcu acaagaaggc cuccgagguc     1800

uacuccgaga ucuccaaggc cgccucccuc accaacaccu ccgucaccgc cgagaagucc     1860

caguacuuca acaccuucac ccuccgcggc accuacaccg gcgagaccuc caagggcgag     1920

uucaaggacu gggacgagau guccaagaag cucgacggca cccucgaguc ccucgccaag     1980

aacuccuggu ccggcuacaa gacccucacc gccuacuuca ccaacuaccg cgucaccucc     2040

gacaacaagg uccaguacga cgucgucuuc cacggcgucc ucaccgacaa cgccgacauc     2100

uccaacaaca aggcccccau cgccaagguc accggccccu ccaccggcgc cgucggccgc     2160

aacaucgagu ucuccggcaa ggacuccaag gacgaggacg gcaagaucgu cuccuacgac     2220

ugggacuucg gcgacggcgc caccucccgc ggcaagaacu ccguccacgc cuacaagaag     2280

gccggcaccu acaacgucac ccucaagguc accgacgaca agggcgccac cgccaccgag     2340

uccuucacca ucgagaucaa gaacgaggac accaccaccc ccaucaccaa ggagauggag     2400

cccaacgacg acaucaagga ggccaacggc cccaucgucg agggcgucac cgucaagggc     2460

gaccucaacg gcuccgacga cgccgacacc uucuacuucg acgucaagga ggacggcgac     2520

gucaccaucg agcuccccua cuccggcucc uccaacuuca ccuggcucgu cuacaaggag     2580

ggcgacgacc agaaccacau cgccuccggc aucgacaaga acaacuccaa ggucggcacc     2640

uucaagucca ccaagggccg ccacuacguc uucaucuaca agcacgacuc cgccuccaac     2700

aucuccuacu cccucaacau caagggccuc ggcaacgaga agcucaagga gaaggagaac     2760

aacgacuccu ccgacaaggc caccgucauc cccaacuuca acaccaccau gcagggcucc     2820

cuccucggcg acgacucccg cgacuacuac uccuucgagg ucaaggagga gggcgagguc     2880

aacaucgagc ucgacaagaa ggacgaguuc ggcgucaccu ggacccucca ccccgagucc     2940

aacaucaacg accgcaucac cuacggccag gucgacggca acaaggucuc caacaagguc     3000

aagcuccgcc ccggcaagua cuaccuccuc gucuacaagu acuccggcuc cggcaacuac     3060

gagcuccgcg ucaacaagug a                                               3081


<210>  318
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  318
augaaguggg ucaccuucau cucccuccuc uuccucuucu ccuccgccua cuccaugaag       60

aagaacaucc ucaagauccu cauggacucc uacuccaagg aguccaagau ccagaccguc      120

cgccgcguca ccuccgucuc ccuccucgcc gucuaccuca ccaugaacac cuccucccuc      180

guccucgcca agcccaucga gaacaccaac gacaccucca ucaagaacgu cgagaagcuc      240

cgcaacgccc ccaacgagga gaacuccaag aaggucgagg acuccaagaa cgacaagguc      300

gagcacguca agaacaucga ggaggccaag gucgagcagg ucgcccccga ggucaagucc      360

aaguccaccc uccgcuccgc cucccgccgc cgccgcaagc gcaucgccaa caccaacucc      420

gagaaguacg acuucgagua ccucaacggc cucuccuaca ccgagcucac caaccucauc      480

aagaacauca aguggaacca gaucaacggc cucuucaacu acuccaccgg cucccagaag      540

uucuucggcg acaagaaccg cguccaggcc aucaucaacg cccuccagga guccggccgc      600

accuacaccg ccaacgacau gaagggcauc gagaccuuca ccgagguccu ccgcgccggc      660

uucuaccucg gcuacuacaa cgacggccuc uccuaccuca acgaccgcaa cuuccaggac      720

aagugcaucc ccgccaugau cgccauccag aagaacccca acuucaagcu cggcaccgcc      780

guccaggacg aggucaucac cucccucggc aagcucaucg gcaacgccuc cgccaacgcc      840

gaggucguca acaacugcgu ccccguccuc aagcaguucc gcgagaaccu caaccaguac      900

gcccccgacu acgucaaggg caccgccguc aacgagcuca ucaagggcau cgaguucgac      960

uucuccggcg ccgccuacga gaaggacguc aagaccaugc ccugguacgg caagaucgac     1020

cccuucauca acgagcucaa ggcccucggc cucuacggca acaucaccuc cgccaccgag     1080

ugggccuccg acgucggcau cuacuaccuc uccaaguucg gccucuacuc caccaaccgc     1140

aacgacaucg uccagucccu cgagaaggcc gucgacaugu acaaguacgg caagaucgcc     1200

uucgucgcca uggagcgcau caccugggac uacgacggca ucggcuccaa cggcaagaag     1260

gucgaccacg acaaguuccu cgacgacgcc gagaagcacu accuccccaa gaccuacacc     1320

uucgacaacg gcaccuucau cauccgcgcc ggcgacaagg ucuccgagga gaagaucaag     1380

cgccucuacu gggccucccg cgaggucaag ucccaguucc accgcgucgu cggcaacgac     1440

aaggcccucg aggucggcaa cgccgacgac guccucacca ugaagaucuu caacuccccc     1500

gaggaguaca aguucaacac caacaucaac ggcgucucca ccgacaacgg cggccucuac     1560

aucgagcccc gcggcaccuu cuacaccuac gagcgcaccc cccagcaguc caucuucucc     1620

cucgaggagc ucuuccgcca cgaguacacc cacuaccucc aggcccgcua ccucgucgac     1680

ggccucuggg gccagggccc cuucuacgag aagaaccgcc ucaccugguu cgacgagggc     1740

accgccgagu ucuucgccgg cuccacccgc accuccggcg uccucccccg caaguccauc     1800

cucggcuacc ucgccaagga caaggucgac caccgcuacu cccucaagaa gacccucaac     1860

uccggcuacg acgacuccga cuggauguuc uacaacuacg gcuucgccgu cgcccacuac     1920

cucuacgaga aggacaugcc caccuucauc aagaugaaca aggccauccu caacaccgac     1980

gucaaguccu acgacgagau caucaagaag cucuccgacg acgccaacaa gaacaccgag     2040

uaccagaacc acauccagga gcucgccgac aaguaccagg gcgccggcau cccccucguc     2100

uccgacgacu accucaagga ccacggcuac aagaaggccu ccgaggucua cuccgagauc     2160

uccaaggccg ccucccucac caacaccucc gucaccgccg agaaguccca guacuucaac     2220

accuucaccc uccgcggcac cuacaccggc gagaccucca agggcgaguu caaggacugg     2280

gacgagaugu ccaagaagcu cgacggcacc cucgaguccc ucgccaagaa cuccuggucc     2340

ggcuacaaga cccucaccgc cuacuucacc aacuaccgcg ucaccuccga caacaagguc     2400

caguacgacg ucgucuucca cggcguccuc accgacaacg ccgacaucuc caacaacaag     2460

gcccccaucg ccaaggucac cggccccucc accggcgccg ucggccgcaa caucgaguuc     2520

uccggcaagg acuccaagga cgaggacggc aagaucgucu ccuacgacug ggacuucggc     2580

gacggcgcca ccucccgcgg caagaacucc guccacgccu acaagaaggc cggcaccuac     2640

aacgucaccc ucaaggucac cgacgacaag ggcgccaccg ccaccgaguc cuucaccauc     2700

gagaucaaga acgaggacac caccaccccc aucaccaagg agauggagcc caacgacgac     2760

aucaaggagg ccaacggccc caucgucgag ggcgucaccg ucaagggcga ccucaacggc     2820

uccgacgacg ccgacaccuu cuacuucgac gucaaggagg acggcgacgu caccaucgag     2880

cuccccuacu ccggcuccuc caacuucacc uggcucgucu acaaggaggg cgacgaccag     2940

aaccacaucg ccuccggcau cgacaagaac aacuccaagg ucggcaccuu caaguccacc     3000

aagggccgcc acuacgucuu caucuacaag cacgacuccg ccuccaacau cuccuacucc     3060

cucaacauca agggccucgg caacgagaag cucaaggaga aggagaacaa cgacuccucc     3120

gacaaggcca ccgucauccc caacuucaac accaccaugc agggcucccu ccucggcgac     3180

gacucccgcg acuacuacuc cuucgagguc aaggaggagg gcgaggucaa caucgagcuc     3240

gacaagaagg acgaguucgg cgucaccugg acccuccacc ccgaguccaa caucaacgac     3300

cgcaucaccu acggccaggu cgacggcaac aaggucucca acaaggucaa gcuccgcccc     3360

ggcaaguacu accuccucgu cuacaaguac uccggcuccg gcaacuacga gcuccgcguc     3420

aacaaguga                                                             3429


<210>  319
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  319
augaacuucc ucaagaucau ccucaaccgc ggcaagacca ugaagcgcaa gugccucucc       60

aagcgccuca ugcucgccau caccauggcc accaucuuca ccgucaacuc cacccucccc      120

aucuacgccg ccgucgacaa gaacaacgcc accgccgccg uccagaacga guccaagcgc      180

uacaccgucu ccuaccucaa gacccucaac uacuacgacc ucgucgaccu ccucgucaag      240

accgagaucg agaaccuccc cgaccucuuc caguacuccu ccgacgccaa ggaguucuac      300

ggcaacaaga cccgcauguc cuucaucaug gacgagaucg gccgccgcgc cccccaguac      360

accgagaucg accacaaggg cauccccacc cucgucgagg ucguccgcgc cggcuucuac      420

cucggcuucc acaacaagga gcucaacgag aucaacaagc gcuccuucaa ggagcgcguc      480

auccccucca uccucgccau ccagaagaac cccaacuuca agcucggcac cgagguccag      540

gacaagaucg ucuccgccac cggccuccuc gccggcaacg agaccgcccc ccccgagguc      600

gucaacaacu ucacccccau ccuccaggac ugcaucaaga acaucgaccg cuacgcccuc      660

gacgaccuca aguccaaggc ccucuucaac guccucgccg cccccaccua cgacaucacc      720

gaguaccucc gcgccaccaa ggagaagccc gagaacaccc ccugguacgg caagaucgac      780

ggcuucauca acgagcucaa gaagcucgcc cucuacggca agaucaacga caacaacucc      840

uggaucaucg acaacggcau cuaccacauc gccccccucg gcaagcucca cuccaacaac      900

aagaucggca ucgagacccu caccgagguc augaaggucu accccuaccu cuccaugcag      960

caccuccagu ccgccgacca gaucaagcgc cacuacgacu ccaaggacgc cgagggcaac     1020

aagauccccc ucgacaaguu caagaaggag ggcaaggaga aguacugccc caagaccuac     1080

accuucgacg acggcaaggu caucaucaag gccggcgccc gcgucgagga ggagaagguc     1140

aagcgccucu acugggccuc caaggagguc aacucccagu ucuuccgcgu cuacggcauc     1200

gacaagcccc ucgaggaggg caaccccgac gacauccuca ccauggucau cuacaacucc     1260

cccgaggagu acaagcucaa cuccguccuc uacggcuacg acaccaacaa cggcggcaug     1320

uacaucgagc ccgagggcac cuucuucacc uacgagcgcg aggcccagga guccaccuac     1380

acccucgagg agcucuuccg ccacgaguac acccacuacc uccagggccg cuacgccguc     1440

cccggccagu ggggccgcac caagcucuac gacaacgacc gccucaccug guacgaggag     1500

ggcggcgccg agcucuucgc cggcuccacc cgcaccuccg gcauccuccc ccgcaagucc     1560

aucgucucca acauccacaa caccacccgc aacaaccgcu acaagcucuc cgacaccguc     1620

cacuccaagu acggcgccuc cuucgaguuc uacaacuacg ccugcauguu cauggacuac     1680

auguacaaca aggacauggg cauccucaac aagcucaacg accucgccaa gaacaacgac     1740

gucgacggcu acgacaacua cauccgcgac cucuccucca acuacgcccu caacgacaag     1800

uaccaggacc acaugcagga gcgcaucgac aacuacgaga accucaccgu ccccuucguc     1860

gccgacgacu accucguccg ccacgccuac aagaacccca acgagaucua cuccgagauc     1920

uccgaggucg ccaagcucaa ggacgccaag uccgagguca agaaguccca guacuucucc     1980

accuucaccc uccgcggcuc cuacaccggc ggcgccucca agggcaagcu cgaggaccag     2040

aaggccauga acaaguucau cgacgacucc cucaagaagc ucgacaccua cuccuggucc     2100

ggcuacaaga cccucaccgc cuacuucacc aacuacaagg ucgacuccuc caaccgcguc     2160

accuacgacg ucgucuucca cggcuaccuc cccaacgagg gcgacuccaa gaacucccuc     2220

cccuacggca agaucaacgg caccuacaag ggcaccgaga aggagaagau caaguucucc     2280

uccgagggcu ccuucgaccc cgacggcaag aucgucuccu acgaguggga cuucggcgac     2340

ggcaacaagu ccaacgagga gaaccccgag cacuccuacg acaaggucgg caccuacacc     2400

gucaagcuca aggucaccga cgacaagggc gaguccuccg ucuccaccac caccgccgag     2460

aucaaggacc ucuccgagaa caagcucccc gucaucuaca ugcacguccc caaguccggc     2520

gcccucaacc agaaggucgu cuucuacggc aagggcaccu acgaccccga cggcuccauc     2580

gccggcuacc agugggacuu cggcgacggc uccgacuucu ccuccgagca gaaccccucc     2640

cacgucuaca ccaagaaggg cgaguacacc gucacccucc gcgucaugga cuccuccggc     2700

cagauguccg agaagaccau gaagaucaag aucaccgacc ccgucuaccc caucggcacc     2760

gagaaggagc ccaacaacuc caaggagacc gccuccggcc ccaucguccc cggcaucccc     2820

gucuccggca ccaucgagaa caccuccgac caggacuacu ucuacuucga cgucaucacc     2880

cccggcgagg ucaagaucga caucaacaag cucggcuacg gcggcgccac cugggucguc     2940

uacgacgaga acaacaacgc cgucuccuac gccaccgacg acggccagaa ccucuccggc     3000

aaguucaagg ccgacaagcc cggccgcuac uacauccacc ucuacauguu caacggcucc     3060

uacaugcccu accgcaucaa caucgagggc uccgucggcc gcuga                     3105


<210>  320
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  320
augaagcgca agugccucuc caagcgccuc augcucgcca ucaccauggc caccaucuuc       60

accgucaacu ccacccuccc caucuacgcc gccgucgaca agaacaacgc caccgccgcc      120

guccagaacg aguccaagcg cuacaccguc uccuaccuca agacccucaa cuacuacgac      180

cucgucgacc uccucgucaa gaccgagauc gagaaccucc ccgaccucuu ccaguacucc      240

uccgacgcca aggaguucua cggcaacaag acccgcaugu ccuucaucau ggacgagauc      300

ggccgccgcg ccccccagua caccgagauc gaccacaagg gcauccccac ccucgucgag      360

gucguccgcg ccggcuucua ccucggcuuc cacaacaagg agcucaacga gaucaacaag      420

cgcuccuuca aggagcgcgu cauccccucc auccucgcca uccagaagaa ccccaacuuc      480

aagcucggca ccgaggucca ggacaagauc gucuccgcca ccggccuccu cgccggcaac      540

gagaccgccc cccccgaggu cgucaacaac uucaccccca uccuccagga cugcaucaag      600

aacaucgacc gcuacgcccu cgacgaccuc aaguccaagg cccucuucaa cguccucgcc      660

gcccccaccu acgacaucac cgaguaccuc cgcgccacca aggagaagcc cgagaacacc      720

cccugguacg gcaagaucga cggcuucauc aacgagcuca agaagcucgc ccucuacggc      780

aagaucaacg acaacaacuc cuggaucauc gacaacggca ucuaccacau cgccccccuc      840

ggcaagcucc acuccaacaa caagaucggc aucgagaccc ucaccgaggu caugaagguc      900

uaccccuacc ucuccaugca gcaccuccag uccgccgacc agaucaagcg ccacuacgac      960

uccaaggacg ccgagggcaa caagaucccc cucgacaagu ucaagaagga gggcaaggag     1020

aaguacugcc ccaagaccua caccuucgac gacggcaagg ucaucaucaa ggccggcgcc     1080

cgcgucgagg aggagaaggu caagcgccuc uacugggccu ccaaggaggu caacucccag     1140

uucuuccgcg ucuacggcau cgacaagccc cucgaggagg gcaaccccga cgacauccuc     1200

accaugguca ucuacaacuc ccccgaggag uacaagcuca acuccguccu cuacggcuac     1260

gacaccaaca acggcggcau guacaucgag cccgagggca ccuucuucac cuacgagcgc     1320

gaggcccagg aguccaccua cacccucgag gagcucuucc gccacgagua cacccacuac     1380

cuccagggcc gcuacgccgu ccccggccag uggggccgca ccaagcucua cgacaacgac     1440

cgccucaccu gguacgagga gggcggcgcc gagcucuucg ccggcuccac ccgcaccucc     1500

ggcauccucc cccgcaaguc caucgucucc aacauccaca acaccacccg caacaaccgc     1560

uacaagcucu ccgacaccgu ccacuccaag uacggcgccu ccuucgaguu cuacaacuac     1620

gccugcaugu ucauggacua cauguacaac aaggacaugg gcauccucaa caagcucaac     1680

gaccucgcca agaacaacga cgucgacggc uacgacaacu acauccgcga ccucuccucc     1740

aacuacgccc ucaacgacaa guaccaggac cacaugcagg agcgcaucga caacuacgag     1800

aaccucaccg uccccuucgu cgccgacgac uaccucgucc gccacgccua caagaacccc     1860

aacgagaucu acuccgagau cuccgagguc gccaagcuca aggacgccaa guccgagguc     1920

aagaaguccc aguacuucuc caccuucacc cuccgcggcu ccuacaccgg cggcgccucc     1980

aagggcaagc ucgaggacca gaaggccaug aacaaguuca ucgacgacuc ccucaagaag     2040

cucgacaccu acuccugguc cggcuacaag acccucaccg ccuacuucac caacuacaag     2100

gucgacuccu ccaaccgcgu caccuacgac gucgucuucc acggcuaccu ccccaacgag     2160

ggcgacucca agaacucccu ccccuacggc aagaucaacg gcaccuacaa gggcaccgag     2220

aaggagaaga ucaaguucuc cuccgagggc uccuucgacc ccgacggcaa gaucgucucc     2280

uacgaguggg acuucggcga cggcaacaag uccaacgagg agaaccccga gcacuccuac     2340

gacaaggucg gcaccuacac cgucaagcuc aaggucaccg acgacaaggg cgaguccucc     2400

gucuccacca ccaccgccga gaucaaggac cucuccgaga acaagcuccc cgucaucuac     2460

augcacgucc ccaaguccgg cgcccucaac cagaaggucg ucuucuacgg caagggcacc     2520

uacgaccccg acggcuccau cgccggcuac cagugggacu ucggcgacgg cuccgacuuc     2580

uccuccgagc agaaccccuc ccacgucuac accaagaagg gcgaguacac cgucacccuc     2640

cgcgucaugg acuccuccgg ccagaugucc gagaagacca ugaagaucaa gaucaccgac     2700

cccgucuacc ccaucggcac cgagaaggag cccaacaacu ccaaggagac cgccuccggc     2760

cccaucgucc ccggcauccc cgucuccggc accaucgaga acaccuccga ccaggacuac     2820

uucuacuucg acgucaucac ccccggcgag gucaagaucg acaucaacaa gcucggcuac     2880

ggcggcgcca ccugggucgu cuacgacgag aacaacaacg ccgucuccua cgccaccgac     2940

gacggccaga accucuccgg caaguucaag gccgacaagc ccggccgcua cuacauccac     3000

cucuacaugu ucaacggcuc cuacaugccc uaccgcauca acaucgaggg cuccgucggc     3060

cgcuga                                                                3066


<210>  321
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  321
augaaguggg ucaccuucau cucccuccuc uuccucuucu ccuccgccua cuccguccag       60

aacgagucca agcgcuacac cgucuccuac cucaagaccc ucaacuacua cgaccucguc      120

gaccuccucg ucaagaccga gaucgagaac cuccccgacc ucuuccagua cuccuccgac      180

gccaaggagu ucuacggcaa caagacccgc auguccuuca ucauggacga gaucggccgc      240

cgcgcccccc aguacaccga gaucgaccac aagggcaucc ccacccucgu cgaggucguc      300

cgcgccggcu ucuaccucgg cuuccacaac aaggagcuca acgagaucaa caagcgcucc      360

uucaaggagc gcgucauccc cuccauccuc gccauccaga agaaccccaa cuucaagcuc      420

ggcaccgagg uccaggacaa gaucgucucc gccaccggcc uccucgccgg caacgagacc      480

gccccccccg aggucgucaa caacuucacc cccauccucc aggacugcau caagaacauc      540

gaccgcuacg cccucgacga ccucaagucc aaggcccucu ucaacguccu cgccgccccc      600

accuacgaca ucaccgagua ccuccgcgcc accaaggaga agcccgagaa cacccccugg      660

uacggcaaga ucgacggcuu caucaacgag cucaagaagc ucgcccucua cggcaagauc      720

aacgacaaca acuccuggau caucgacaac ggcaucuacc acaucgcccc ccucggcaag      780

cuccacucca acaacaagau cggcaucgag acccucaccg aggucaugaa ggucuacccc      840

uaccucucca ugcagcaccu ccaguccgcc gaccagauca agcgccacua cgacuccaag      900

gacgccgagg gcaacaagau cccccucgac aaguucaaga aggagggcaa ggagaaguac      960

ugccccaaga ccuacaccuu cgacgacggc aaggucauca ucaaggccgg cgcccgcguc     1020

gaggaggaga aggucaagcg ccucuacugg gccuccaagg aggucaacuc ccaguucuuc     1080

cgcgucuacg gcaucgacaa gccccucgag gagggcaacc ccgacgacau ccucaccaug     1140

gucaucuaca acucccccga ggaguacaag cucaacuccg uccucuacgg cuacgacacc     1200

aacaacggcg gcauguacau cgagcccgag ggcaccuucu ucaccuacga gcgcgaggcc     1260

caggagucca ccuacacccu cgaggagcuc uuccgccacg aguacaccca cuaccuccag     1320

ggccgcuacg ccguccccgg ccaguggggc cgcaccaagc ucuacgacaa cgaccgccuc     1380

accugguacg aggagggcgg cgccgagcuc uucgccggcu ccacccgcac cuccggcauc     1440

cucccccgca aguccaucgu cuccaacauc cacaacacca cccgcaacaa ccgcuacaag     1500

cucuccgaca ccguccacuc caaguacggc gccuccuucg aguucuacaa cuacgccugc     1560

auguucaugg acuacaugua caacaaggac augggcaucc ucaacaagcu caacgaccuc     1620

gccaagaaca acgacgucga cggcuacgac aacuacaucc gcgaccucuc cuccaacuac     1680

gcccucaacg acaaguacca ggaccacaug caggagcgca ucgacaacua cgagaaccuc     1740

accguccccu ucgucgccga cgacuaccuc guccgccacg ccuacaagaa ccccaacgag     1800

aucuacuccg agaucuccga ggucgccaag cucaaggacg ccaaguccga ggucaagaag     1860

ucccaguacu ucuccaccuu cacccuccgc ggcuccuaca ccggcggcgc cuccaagggc     1920

aagcucgagg accagaaggc caugaacaag uucaucgacg acucccucaa gaagcucgac     1980

accuacuccu gguccggcua caagacccuc accgccuacu ucaccaacua caaggucgac     2040

uccuccaacc gcgucaccua cgacgucguc uuccacggcu accuccccaa cgagggcgac     2100

uccaagaacu cccuccccua cggcaagauc aacggcaccu acaagggcac cgagaaggag     2160

aagaucaagu ucuccuccga gggcuccuuc gaccccgacg gcaagaucgu cuccuacgag     2220

ugggacuucg gcgacggcaa caaguccaac gaggagaacc ccgagcacuc cuacgacaag     2280

gucggcaccu acaccgucaa gcucaagguc accgacgaca agggcgaguc cuccgucucc     2340

accaccaccg ccgagaucaa ggaccucucc gagaacaagc uccccgucau cuacaugcac     2400

guccccaagu ccggcgcccu caaccagaag gucgucuucu acggcaaggg caccuacgac     2460

cccgacggcu ccaucgccgg cuaccagugg gacuucggcg acggcuccga cuucuccucc     2520

gagcagaacc ccucccacgu cuacaccaag aagggcgagu acaccgucac ccuccgcguc     2580

auggacuccu ccggccagau guccgagaag accaugaaga ucaagaucac cgaccccguc     2640

uaccccaucg gcaccgagaa ggagcccaac aacuccaagg agaccgccuc cggccccauc     2700

guccccggca uccccgucuc cggcaccauc gagaacaccu ccgaccagga cuacuucuac     2760

uucgacguca ucacccccgg cgaggucaag aucgacauca acaagcucgg cuacggcggc     2820

gccaccuggg ucgucuacga cgagaacaac aacgccgucu ccuacgccac cgacgacggc     2880

cagaaccucu ccggcaaguu caaggccgac aagcccggcc gcuacuacau ccaccucuac     2940

auguucaacg gcuccuacau gcccuaccgc aucaacaucg agggcuccgu cggccgcuga     3000


<210>  322
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  322
augaaguggg ucaccuucau cucccuccuc uuccucuucu ccuccgccua cuccaugaag       60

cgcaagugcc ucuccaagcg ccucaugcuc gccaucacca uggccaccau cuucaccguc      120

aacuccaccc uccccaucua cgccgccguc gacaagaaca acgccaccgc cgcccgccgc      180

cgccgcaagc gcguccagaa cgaguccaag cgcuacaccg ucuccuaccu caagacccuc      240

aacuacuacg accucgucga ccuccucguc aagaccgaga ucgagaaccu ccccgaccuc      300

uuccaguacu ccuccgacgc caaggaguuc uacggcaaca agacccgcau guccuucauc      360

auggacgaga ucggccgccg cgccccccag uacaccgaga ucgaccacaa gggcaucccc      420

acccucgucg aggucguccg cgccggcuuc uaccucggcu uccacaacaa ggagcucaac      480

gagaucaaca agcgcuccuu caaggagcgc gucauccccu ccauccucgc cauccagaag      540

aaccccaacu ucaagcucgg caccgagguc caggacaaga ucgucuccgc caccggccuc      600

cucgccggca acgagaccgc cccccccgag gucgucaaca acuucacccc cauccuccag      660

gacugcauca agaacaucga ccgcuacgcc cucgacgacc ucaaguccaa ggcccucuuc      720

aacguccucg ccgcccccac cuacgacauc accgaguacc uccgcgccac caaggagaag      780

cccgagaaca cccccuggua cggcaagauc gacggcuuca ucaacgagcu caagaagcuc      840

gcccucuacg gcaagaucaa cgacaacaac uccuggauca ucgacaacgg caucuaccac      900

aucgcccccc ucggcaagcu ccacuccaac aacaagaucg gcaucgagac ccucaccgag      960

gucaugaagg ucuaccccua ccucuccaug cagcaccucc aguccgccga ccagaucaag     1020

cgccacuacg acuccaagga cgccgagggc aacaagaucc cccucgacaa guucaagaag     1080

gagggcaagg agaaguacug ccccaagacc uacaccuucg acgacggcaa ggucaucauc     1140

aaggccggcg cccgcgucga ggaggagaag gucaagcgcc ucuacugggc cuccaaggag     1200

gucaacuccc aguucuuccg cgucuacggc aucgacaagc cccucgagga gggcaacccc     1260

gacgacaucc ucaccauggu caucuacaac ucccccgagg aguacaagcu caacuccguc     1320

cucuacggcu acgacaccaa caacggcggc auguacaucg agcccgaggg caccuucuuc     1380

accuacgagc gcgaggccca ggaguccacc uacacccucg aggagcucuu ccgccacgag     1440

uacacccacu accuccaggg ccgcuacgcc guccccggcc aguggggccg caccaagcuc     1500

uacgacaacg accgccucac cugguacgag gagggcggcg ccgagcucuu cgccggcucc     1560

acccgcaccu ccggcauccu cccccgcaag uccaucgucu ccaacaucca caacaccacc     1620

cgcaacaacc gcuacaagcu cuccgacacc guccacucca aguacggcgc cuccuucgag     1680

uucuacaacu acgccugcau guucauggac uacauguaca acaaggacau gggcauccuc     1740

aacaagcuca acgaccucgc caagaacaac gacgucgacg gcuacgacaa cuacauccgc     1800

gaccucuccu ccaacuacgc ccucaacgac aaguaccagg accacaugca ggagcgcauc     1860

gacaacuacg agaaccucac cguccccuuc gucgccgacg acuaccucgu ccgccacgcc     1920

uacaagaacc ccaacgagau cuacuccgag aucuccgagg ucgccaagcu caaggacgcc     1980

aaguccgagg ucaagaaguc ccaguacuuc uccaccuuca cccuccgcgg cuccuacacc     2040

ggcggcgccu ccaagggcaa gcucgaggac cagaaggcca ugaacaaguu caucgacgac     2100

ucccucaaga agcucgacac cuacuccugg uccggcuaca agacccucac cgccuacuuc     2160

accaacuaca aggucgacuc cuccaaccgc gucaccuacg acgucgucuu ccacggcuac     2220

cuccccaacg agggcgacuc caagaacucc cuccccuacg gcaagaucaa cggcaccuac     2280

aagggcaccg agaaggagaa gaucaaguuc uccuccgagg gcuccuucga ccccgacggc     2340

aagaucgucu ccuacgagug ggacuucggc gacggcaaca aguccaacga ggagaacccc     2400

gagcacuccu acgacaaggu cggcaccuac accgucaagc ucaaggucac cgacgacaag     2460

ggcgaguccu ccgucuccac caccaccgcc gagaucaagg accucuccga gaacaagcuc     2520

cccgucaucu acaugcacgu ccccaagucc ggcgcccuca accagaaggu cgucuucuac     2580

ggcaagggca ccuacgaccc cgacggcucc aucgccggcu accaguggga cuucggcgac     2640

ggcuccgacu ucuccuccga gcagaacccc ucccacgucu acaccaagaa gggcgaguac     2700

accgucaccc uccgcgucau ggacuccucc ggccagaugu ccgagaagac caugaagauc     2760

aagaucaccg accccgucua ccccaucggc accgagaagg agcccaacaa cuccaaggag     2820

accgccuccg gccccaucgu ccccggcauc cccgucuccg gcaccaucga gaacaccucc     2880

gaccaggacu acuucuacuu cgacgucauc acccccggcg aggucaagau cgacaucaac     2940

aagcucggcu acggcggcgc caccuggguc gucuacgacg agaacaacaa cgccgucucc     3000

uacgccaccg acgacggcca gaaccucucc ggcaaguuca aggccgacaa gcccggccgc     3060

uacuacaucc accucuacau guucaacggc uccuacaugc ccuaccgcau caacaucgag     3120

ggcuccgucg gccgcuga                                                   3138


<210>  323
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  323
augggcaccu ggauccucuu cgccugccuc cucggcgccg ccuucgccau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg agguccucac cccccucaag      120

ugguaccagu ccauccgccc ccccuacccc uccuacggcu acgagcccau gggcggcugg      180

cuccaccacc agaucauccc cguccucucc cagcagcacc cccccaccca cacccuccag      240

ccccaccacc acauccccgu cguccccgcc cagcagcccg ucauccccca gcagcccaug      300

augcccgucc ccggccagca cuccaugacc cccauccagc accaccagcc caaccucccc      360

ccccccgccc agcagcccua ccagccccag cccguccagc cccagcccca ccagcccaug      420

cagccccagc cccccgucca ccccaugcag ccccuccccc cccagccccc ccuccccccc      480

auguucccca ugcagccccu cccccccaug cuccccgacc ucacccucga ggccuggccc      540

uccaccgaca agaccaagcg cgaggagguc gacuga                                576


<210>  324
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  324
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgagguccuc       60

accccccuca agugguacca guccauccgc ccccccuacc ccuccuacgg cuacgagccc      120

augggcggcu gguga                                                       135


<210>  325
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  325
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgagguccuc       60

accccccuca agugguacca guccauccgc ccccccccca ugcuccccga ccucacccuc      120

gaggccuggc ccuccaccga caagaccaag cgcgaggagg ucgacuga                   168


<210>  326
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  326
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

cagaccuggg ccaugccccu ccccccccac cccggccacc ccggcuacau caacuucucc      120

uacgaggucc ucaccccccu caagugguac caguccaucc gcccccccua ccccuccuac      180

ggcuacgagc ccaugggcgg cugguga                                          207


<210>  327
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  327
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

cagaccuggg ccaugccccu ccccccccac cccggccacc ccggcuacau caacuucucc      120

uacgaggucc ucaccccccu caagugguac caguccaucc gccccccccc caugcucccc      180

gaccucaccc ucgaggccug gcccuccacc gacaagacca agcgcgagga ggucgacuga      240


<210>  328
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  328
augggcaccu ggauccucuu cgccugccuc gucggcgccg ccuucgccau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg agguccucac cccccucaag      120

ugguaccagu ccaugauccg cccccccuac uccuccuacg gcuacgagcc caugggcggc      180

uggcuccacc accagaucau ccccgucguc ucccagcagc acccccucac ccacacccuc      240

cagucccacc accacauccc cgucgucccc gcccagcagc cccgcguccg ccagcaggcc      300

cucaugcccg uccccggcca gcaguccaug acccccaccc agcaccacca gcccaaccuc      360

ccccuccccg cccagcagcc cuuccagccc cagcccgucc agccccagcc ccaccagccc      420

augcagcccc agccccccgu ccagcccaug cagccccucc ucccccagcc cccccucccc      480

cccauguucc cccuccgccc ccuccccccc auccuccccg accuccaccu cgaggccugg      540

cccgccaccg acaagaccaa gcaggaggag gucgacuga                             579


<210>  329
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  329
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgagguccuc       60

accccccuca agugguacca guccaugauc cgcccccccu acuccuccua cggcuacgag      120

cccaugggcg gcugguga                                                    138


<210>  330
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  330
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgagguccuc       60

accccccuca agugguacca guccaugauc cgcccccccc ccauccuccc cgaccuccac      120

cucgaggccu ggcccgccac cgacaagacc aagcaggagg aggucgacug a               171


<210>  331
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  331
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

cagaccuggg ccaugccccu ccccccccac cccggccacc ccggcuacau caacuucucc      120

uacgaggucc ucaccccccu caagugguac caguccauga uccgcccccc cuacuccucc      180

uacggcuacg agcccauggg cggcugguga                                       210


<210>  332
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  332
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

cagaccuggg ccaugccccu ccccccccac cccggccacc ccggcuacau caacuucucc      120

uacgaggucc ucaccccccu caagugguac caguccauga uccgcccccc ccccauccuc      180

cccgaccucc accucgaggc cuggcccgcc accgacaaga ccaagcagga ggaggucgac      240

uga                                                                    243


<210>  333
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  333
augggcaccu ggauccucuu cgccugccuc cucggcgccg ccuucuccau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg agguccucac cccccucaag      120

ugguaccaga acaugauccg ccaccccuac accuccuacg gcuacgagcc caugggcggc      180

uggcuccacc accagaucau ccccgucguc ucccagcaga ccccccaguc ccacgcccuc      240

cagccccacc accacauccc cauggucccc gcccagcagc ccggcauccc ccagcagccc      300

augaugcccc uccccggcca gcacuccaug acccccaccc agcaccacca gcccaaccuc      360

ccccuccccg cccagcagcc cuuccagccc cagcccgucc agccccagcc ccaccagccc      420

cuccagcccc agucccccau gcaccccauc cagccccucc ucccccagcc cccccucccc      480

cccauguucu ccaugcaguc ccuccucccc gaccuccccc ucgaggccug gcccgccacc      540

gacaagacca agcgcgagga ggucgacuga                                       570


<210>  334
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  334
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgagguccuc       60

accccccuca agugguacca gaacaugauc cgccaccccu acaccuccua cggcuacgag      120

cccaugggcg gcugguga                                                    138


<210>  335
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  335
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgagguccuc       60

accccccuca agugguacca gaacaugauc cgccaccccu cccuccuccc cgaccucccc      120

cucgaggccu ggcccgccac cgacaagacc aagcgcgagg aggucgacug a               171


<210>  336
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  336
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

cagaccuggg ccaugccccu ccccccccac cccggccacc ccggcuacau caacuucucc      120

uacgaggucc ucaccccccu caagugguac cagaacauga uccgccaccc cuacaccucc      180

uacggcuacg agcccauggg cggcugguga                                       210


<210>  337
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  337
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

cagaccuggg ccaugccccu ccccccccac cccggccacc ccggcuacau caacuucucc      120

uacgaggucc ucaccccccu caagugguac cagaacauga uccgccaccc cucccuccuc      180

cccgaccucc cccucgaggc cuggcccgcc accgacaaga ccaagcgcga ggaggucgac      240

uga                                                                    243


<210>  338
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  338
augggcaccu ggauccucuu cgccugccuc cucggcgccg ccuucuccau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuaca uccgccaccc cuacaccucc      120

uacggcuacg agcccauggg cggcuggcuc caccaccaga ucauccccgu cgucucccag      180

cagacccccc agucccacgc ccuccagccc caccaccaca uccccauggu ccccgcccag      240

cagcccggca ucccccagca gcccaugaug ccccuccccg gccagcacuc caugaccccc      300

acccagcacc accagcccaa ccucccccuc cccgcccagc agcccuucca gccccagccc      360

guccagcccc agccccacca gccccuccag ccccaguccc ccaugcaccc cauccagccc      420

cuccuccccc agcccccccu cccccccaug uucuccaugc agucccuccu ccccgaccuc      480

ccccucgagg ccuggcccgc caccgacaag accaagcgcg aggaggucga cuga            534


<210>  339
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  339
augggcaccu ggaucuucuu cgccugccuc cucggcgccu cccucgccau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg agguccucac cccccucaag      120

ugguaccaga acaugauccg ccaccccuac accuccuacg gcuacgagcc caugggcggc      180

uggcuccacc accagaucau ccccgucguc ucccagcaga ccccccaguc ccacgcccuc      240

cagccccacc accacauccc cauggucccc gcccagcagc ccggcauccc ccagcagccc      300

augaugcccc uccccggcca gcacuccaug acccccaccc agcaccacca gcccaaccuc      360

ccccuccccg cccagcagcc cuuccagccc cagcccgucc agccccagcc ccaccagccc      420

cuccagcccc agucccccau gcaccccauc cagccccucc ucccccagcc cccccucccc      480

cccauguucu ccaugcaguc ccuccucccc gaccuccccc ucgaggccug gcccgccacc      540

gacaagacca agcgcgagga ggucgacuga                                       570


<210>  340
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  340
augggcaccu ggauccucuu cgccugccuc cucggcgccg ccuucuccau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg agguccucac cccccucaag      120

ugguaccaga acaugauccg ccaccccucc cuccuccccg accucccccu cgaggccugg      180

cccgccaccg acaagaccaa gcgcgaggag gucgacuga                             219


<210>  341
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  341
augggcaccu ggauccucuu cgccugccuc cucggcgccg ccuucuccau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg aggaccucua ccucgaggcc      120

auccgcaucg accgcaccgc cuucguccuc accccccuca agugguacca gaacaugauc      180

cgccaccccu acaccuccua cggcuacgag cccaugggcg gcuggcucca ccaccagauc      240

auccccgucg ucucccagca gaccccccag ucccacgccc uccagcccca ccaccacauc      300

cccauggucc ccgcccagca gcccggcauc ccccagcagc ccaugaugcc ccuccccggc      360

cagcacucca ugacccccac ccagcaccac cagcccaacc ucccccuccc cgcccagcag      420

cccuuccagc cccagcccgu ccagccccag ccccaccagc cccuccagcc ccaguccccc      480

augcacccca uccagccccu ccucccccag cccccccucc cccccauguu cuccaugcag      540

ucccuccucc ccgaccuccc ccucgaggcc uggcccgcca ccgacaagac caagcgcgag      600

gaggucgacu ga                                                          612


<210>  342
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  342
augggcaccu ggauccucuu cgccugccuc cucggcgccg ccuucuccau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg agguccucac cccccucaag      120

ugguaccaga acaugauccg ccaccccacc ccccaguccc acgcccucca gccccaccac      180

cacaucccca ugguccccgc ccagcagccc ggcauccccc agcagcccau gaugccccuc      240

cccggccagc acuccaugac ccccacccag caccaccagc ccaaccuccc ccuccccgcc      300

cagcagcccu uccagcccca gcccguccag ccccagcccc accagccccu ccagccccag      360

ucccccaugc accccaucca gccccuccuc ccccagcccc cccucccccc cauguucucc      420

augcaguccc uccuccccga ccucccccuc gaggccuggc ccgccaccga caagaccaag      480

cgcgaggagg ucgacuga                                                    498


<210>  343
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  343
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgagguccuc       60

accccccuca agugguacca gaacaugauc cgccaccccu acaccuccua cggcuacgag      120

cccaugggcg gcuggcucca ccaccagauc auccccgucg ucucccagca gaccccccag      180

ucccacgccc uccagcccca ccaccacauc cccauggucc ccgcccagca gcccggcauc      240

ccccagcagc ccaugaugcc ccuccccggc cagcacucca ugacccccac ccagcaccac      300

cagcccaacc ucccccuccc cgcccagcag cccuuccagc cccagcccgu ccagccccag      360

ccccaccagc cccuccagcc ccaguccccc augcacccca uccagccccu ccucccccag      420

cccccccucc cccccauguu cuccaugcag ucccuccucc ccgaccuccc ccucgaggcc      480

uggcccgcca ccgacaagac caagcgcgag gaggucgacu ga                         522


<210>  344
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  344
augcccggcg ucgcccgccu cccccuccuc cucggccucc uccuccuccc ccgccccggc       60

cgcccccucg accucgccga cuacaccuac gaccucgccg aggaggacga cuccgagccc      120

cucaacuaca aggaccccug caaggccgcc gccuuccucg gcgacaucgc ccucgacgag      180

gaggaccucc gcgccuucca gguccagcag gccgucgacc uccgccgcca caccgcccgc      240

aaguccucca ucaaggccgc cguccccggc aacaccucca cccccuccug ccaguccacc      300

aacggccagc cccagcgcgg cgccugcggc cgcuggcgcg gccgcucccg cucccgccgc      360

gccgccaccu cccgccccga gcgcgucugg cccgacggcg ucauccccuu cgucaucggc      420

ggcaacuuca ccggcuccca gcgcgccguc uuccgccagg ccaugcgcca cugggagaag      480

cacaccugcg ucaccuuccu cgagcgcacc gacgaggacu ccuacaucgu cuucaccuac      540

cgccccugcg gcugcugcuc cuacgucggc cgccgcggcg gcggccccca ggccaucucc      600

aucggcaaga acugcgacaa guucggcauc gucguccacg agcucggcca cgucgucggc      660

uucuggcacg agcacacccg ccccgaccgc gaccgccacg ucuccaucgu ccgcgagaac      720

auccagcccg gccaggagua caacuuccuc aagauggagc cccaggaggu cgagucccuc      780

ggcgagaccu acgacuucga cuccaucaug cacuacgccc gcaacaccuu cucccgcggc      840

aucuuccucg acaccaucgu ccccaaguac gaggucaacg gcgucaagcc ccccaucggc      900

cagcgcaccc gccucuccaa gggcgacauc gcccaggccc gcaagcucua caagugcccc      960

gccugcggcg agacccucca ggacuccacc ggcaacuucu ccucccccga guaccccaac     1020

ggcuacuccg cccacaugca cugcgucugg cgcaucuccg ucacccccgg cgagaagauc     1080

auccucaacu ucaccucccu cgaccucuac cgcucccgcc ucugcuggua cgacuacguc     1140

gagguccgcg acggcuucug gcgcaaggcc ccccuccgcg gccgcuucug cggcuccaag     1200

cuccccgagc ccaucgucuc caccgacucc cgccucuggg ucgaguuccg cuccuccucc     1260

aacugggucg gcaagggcuu cuucgccguc uacgaggcca ucugcggcgg cgacgucaag     1320

aaggacuacg gccacaucca gucccccaac uaccccgacg acuaccgccc cuccaagguc     1380

ugcaucuggc gcauccaggu cuccgagggc uuccacgucg gccucaccuu ccaguccuuc     1440

gagaucgagc gccacgacuc cugcgccuac gacuaccucg agguccgcga cggccacucc     1500

gaguccucca cccucaucgg ccgcuacugc ggcuacgaga agcccgacga caucaagucc     1560

accuccuccc gccucuggcu caaguucguc uccgacggcu ccaucaacaa ggccggcuuc     1620

gccgucaacu ucuucaagga ggucgacgag ugcucccgcc ccaaccgcgg cggcugcgag     1680

cagcgcugcc ucaacacccu cggcuccuac aagugcuccu gcgaccccgg cuacgagcuc     1740

gcccccgaca agcgccgcug cgaggccgcc ugcggcggcu uccucaccaa gcucaacggc     1800

uccaucaccu cccccggcug gcccaaggag uaccccccca acaagaacug caucuggcag     1860

cucgucgccc ccacccagua ccgcaucucc cuccaguucg acuucuucga gaccgagggc     1920

aacgacgucu gcaaguacga cuucgucgag guccgcuccg gccucaccgc cgacuccaag     1980

cuccacggca aguucugcgg cuccgagaag cccgagguca ucaccuccca guacaacaac     2040

augcgcgucg aguucaaguc cgacaacacc gucuccaaga agggcuucaa ggcccacuuc     2100

uucuccgaca aggacgagug cuccaaggac aacggcggcu gccagcagga cugcgucaac     2160

accuucggcu ccuacgagug ccagugccgc uccggcuucg uccuccacga caacaagcac     2220

gacugcaagg aggccggcug cgaccacaag gucaccucca ccuccggcac caucaccucc     2280

cccaacuggc ccgacaagua ccccuccaag aaggagugca ccugggccau cuccuccacc     2340

cccggccacc gcgucaagcu caccuucaug gagauggaca ucgaguccca gcccgagugc     2400

gccuacgacc accucgaggu cuucgacggc cgcgacgcca aggcccccgu ccucggccgc     2460

uucugcggcu ccaagaagcc cgagcccguc cucgccaccg gcucccgcau guuccuccgc     2520

uucuacuccg acaacuccgu ccagcgcaag ggcuuccagg ccucccacgc caccgagugc     2580

ggcggccagg uccgcgccga cgucaagacc aaggaccucu acucccacgc ccaguucggc     2640

gacaacaacu accccggcgg cgucgacugc gaguggguca ucgucgccga ggagggcuac     2700

ggcgucgagc ucgucuucca gaccuucgag gucgaggagg agaccgacug cggcuacgac     2760

uacauggagc ucuucgacgg cuacgacucc accgcccccc gccucggccg cuacugcggc     2820

uccggccccc ccgaggaggu cuacuccgcc ggcgacuccg uccucgucaa guuccacucc     2880

gacgacacca ucaccaagaa gggcuuccac cuccgcuaca ccuccaccaa guuccaggac     2940

acccuccacu cccgcaagug a                                               2961


<210>  345
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  345
auggucgccg gcacccgcug ccuccucgcc cuccuccucc cccagguccu ccucggcggc       60

gccgccggcc ucguccccga gcucggccgc cgcaaguucg ccgccgccuc cuccggccgc      120

cccuccuccc agcccuccga cgagguccuc uccgaguucg agcuccgccu ccucuccaug      180

uucggccuca agcagcgccc cacccccucc cgcgacgccg ucgucccccc cuacaugcuc      240

gaccucuacc gccgccacuc cggccagccc ggcucccccg cccccgacca ccgccucgag      300

cgcgccgccu cccgcgccaa caccguccgc uccuuccacc acgaggaguc ccucgaggag      360

cuccccgaga ccuccggcaa gaccacccgc cgcuucuucu ucaaccucuc cuccaucccc      420

accgaggagu ucaucaccuc cgccgagcuc caggucuucc gcgagcagau gcaggacgcc      480

cucggcaaca acuccuccuu ccaccaccgc aucaacaucu acgagaucau caagcccgcc      540

accgccaacu ccaaguuccc cgucacccgc cuccucgaca cccgccucgu caaccagaac      600

gccucccgcu gggaguccuu cgacgucacc cccgccguca ugcgcuggac cgcccagggc      660

cacgccaacc acggcuucgu cgucgagguc gcccaccucg aggagaagca gggcgucucc      720

aagcgccacg uccgcaucuc ccgcucccuc caccaggacg agcacuccug gucccagauc      780

cgcccccucc ucgucaccuu cggccacgac ggcaagggcc acccccucca caagcgcgag      840

aagcgccagg ccaagcacaa gcagcgcaag cgccucaagu ccuccugcaa gcgccacccc      900

cucuacgucg acuucuccga cgucggcugg aacgacugga ucgucgcccc ccccggcuac      960

cacgccuucu acugccacgg cgagugcccc uucccccucg ccgaccaccu caacuccacc     1020

aaccacgcca ucguccagac ccucgucaac uccgucaacu ccaagauccc caaggccugc     1080

ugcgucccca ccgagcucuc cgccaucucc augcucuacc ucgacgagaa cgagaagguc     1140

guccucaaga acuaccagga cauggucguc gagggcugcg gcugccgcug a              1191


<210>  346
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  346
augauccccg gcaaccgcau gcucaugguc guccuccucu gccagguccu ccucggcggc       60

gccucccacg ccucccucau ccccgagacc ggcaagaaga aggucgccga gauccagggc      120

cacgccggcg gccgccgcuc cggccagucc cacgagcucc uccgcgacuu cgaggccacc      180

cuccuccaga uguucggccu ccgccgccgc ccccagcccu ccaaguccgc cgucaucccc      240

gacuacaugc gcgaccucua ccgccuccag uccggcgagg aggaggagga gcagauccac      300

uccaccggcc ucgaguaccc cgagcgcccc gccucccgcg ccaacaccgu ccgcuccuuc      360

caccacgagg agcaccucga gaacaucccc ggcaccuccg agaacuccgc cuuccgcuuc      420

cucuucaacc ucuccuccau ccccgagaac gaggucaucu ccuccgccga gcuccgccuc      480

uuccgcgagc aggucgacca gggccccgac ugggagcgcg gcuuccaccg caucaacauc      540

uacgagguca ugaagccccc cgccgagguc guccccggcc accucaucac ccgccuccuc      600

gacacccgcc ucguccacca caacgucacc cgcugggaga ccuucgacgu cucccccgcc      660

guccuccgcu ggacccgcga gaagcagccc aacuacggcc ucgccaucga ggucacccac      720

cuccaccaga cccgcaccca ccagggccag cacguccgca ucucccgcuc ccucccccag      780

ggcuccggca acugggccca gcuccgcccc cuccucguca ccuucggcca cgacggccgc      840

ggccacgccc ucacccgccg ccgccgcgcc aagcgcuccc ccaagcacca cucccagcgc      900

gcccgcaaga agaacaagaa cugccgccgc cacucccucu acgucgacuu cuccgacguc      960

ggcuggaacg acuggaucgu cgcccccccc ggcuaccagg ccuucuacug ccacggcgac     1020

ugccccuucc cccucgccga ccaccucaac uccaccaacc acgccaucgu ccagacccuc     1080

gucaacuccg ucaacuccuc cauccccaag gccugcugcg uccccaccga gcucuccgcc     1140

aucuccaugc ucuaccucga cgaguacgac aaggucgucc ucaagaacua ccaggagaug     1200

gucgucgagg gcugcggcug ccgcuga                                         1227


<210>  347
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  347
augcccggcc ucggccgccg cgcccagugg cucugcuggu gguggggccu ccucugcucc       60

ugcugcggcc cccccccccu ccgccccccc cuccccgccg ccgccgccgc cgccgccggc      120

ggccagcucc ucggcgacgg cggcuccccc ggccgcaccg agcagccccc ccccuccccc      180

caguccuccu ccggcuuccu cuaccgccgc cucaagaccc aggagaagcg cgagaugcag      240

aaggagaucc ucuccguccu cggccucccc caccgccccc gcccccucca cggccuccag      300

cagccccagc cccccgcccu ccgccagcag gaggagcagc agcagcagca gcagcucccc      360

cgcggcgagc ccccccccgg ccgccucaag uccgcccccc ucuucaugcu cgaccucuac      420

aacgcccucu ccgccgacaa cgacgaggac ggcgccuccg agggcgagcg ccagcagucc      480

uggccccacg aggccgccuc cuccucccag cgccgccagc ccccccccgg cgccgcccac      540

ccccucaacc gcaagucccu ccucgccccc ggcuccggcu ccggcggcgc cuccccccuc      600

accuccgccc aggacuccgc cuuccucaac gacgccgaca uggucauguc cuucgucaac      660

cucgucgagu acgacaagga guucuccccc cgccagcgcc accacaagga guucaaguuc      720

aaccucuccc agauccccga gggcgagguc gucaccgccg ccgaguuccg caucuacaag      780

gacugcguca ugggcuccuu caagaaccag accuuccuca ucuccaucua ccagguccuc      840

caggagcacc agcaccgcga cuccgaccuc uuccuccucg acacccgcgu cgucugggcc      900

uccgaggagg gcuggcucga guucgacauc accgccaccu ccaaccucug ggucgucacc      960

ccccagcaca acaugggccu ccagcucucc gucgucaccc gcgacggcgu ccacguccac     1020

ccccgcgccg ccggccucgu cggccgcgac ggccccuacg acaagcagcc cuucaugguc     1080

gccuucuuca aggucuccga gguccacguc cgcaccaccc gcuccgccuc cucccgccgc     1140

cgccagcagu cccgcaaccg cuccacccag ucccaggacg ucgcccgcgu cuccuccgcc     1200

uccgacuaca acuccuccga gcucaagacc gccugccgca agcacgagcu cuacgucucc     1260

uuccaggacc ucggcuggca ggacuggauc aucgccccca agggcuacgc cgccaacuac     1320

ugcgacggcg agugcuccuu cccccucaac gcccacauga acgccaccaa ccacgccauc     1380

guccagaccc ucguccaccu caugaacccc gaguacgucc ccaagcccug cugcgccccc     1440

accaagcuca acgccaucuc cguccucuac uucgacgaca acuccaacgu cauccucaag     1500

aaguaccgca acauggucgu ccgcgccugc ggcugccacu ga                        1542


<210>  348
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  348
augcacgucc gcucccuccg cgccgccgcc ccccacuccu ucgucgcccu cugggccccc       60

cucuuccucc uccgcuccgc ccucgccgac uucucccucg acaacgaggu ccacuccucc      120

uucauccacc gccgccuccg cucccaggag cgccgcgaga ugcagcgcga gauccucucc      180

auccucggcc ucccccaccg cccccgcccc caccuccagg gcaagcacaa cuccgccccc      240

auguucaugc ucgaccucua caacgccaug gccgucgagg agggcggcgg ccccggcggc      300

cagggcuucu ccuaccccua caaggccguc uucuccaccc agggcccccc ccucgccucc      360

cuccaggacu cccacuuccu caccgacgcc gacaugguca uguccuucgu caaccucguc      420

gagcacgaca aggaguucuu ccacccccgc uaccaccacc gcgaguuccg cuucgaccuc      480

uccaagaucc ccgagggcga ggccgucacc gccgccgagu uccgcaucua caaggacuac      540

auccgcgagc gcuucgacaa cgagaccuuc cgcaucuccg ucuaccaggu ccuccaggag      600

caccucggcc gcgaguccga ccucuuccuc cucgacuccc gcacccucug ggccuccgag      660

gagggcuggc ucgucuucga caucaccgcc accuccaacc acugggucgu caacccccgc      720

cacaaccucg gccuccagcu cuccgucgag acccucgacg gccaguccau caaccccaag      780

cucgccggcc ucaucggccg ccacggcccc cagaacaagc agcccuucau ggucgccuuc      840

uucaaggcca ccgaggucca cuuccgcucc auccgcucca ccggcuccaa gcagcgcucc      900

cagaaccgcu ccaagacccc caagaaccag gaggcccucc gcauggccaa cgucgccgag      960

aacuccuccu ccgaccagcg ccaggccugc aagaagcacg agcucuacgu cuccuuccgc     1020

gaccucggcu ggcaggacug gaucaucgcc cccgagggcu acgccgccua cuacugcgag     1080

ggcgagugcg ccuucccccu caacuccuac augaacgcca ccaaccacgc caucguccag     1140

acccucgucc acuucaucaa ccccgagacc guccccaagc ccugcugcgc ccccacccag     1200

cucaacgcca ucuccguccu cuacuucgac gacuccucca acgucauccu caagaaguac     1260

cgcaacaugg ucguccgcgc cugcggcugc cacuga                               1296


<210>  349
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  349
augaaggccu ccgccgcccu ccucugccuc cuccucaccg ccgccgccuu cuccccccag       60

ggccucgccc agcccgucgg caucaacacc uccaccaccu gcugcuaccg cuucaucaac      120

aagaagaucc ccaagcagcg ccucgagucc uaccgccgca ccaccuccuc ccacugcccc      180

cgcgaggccg ucaucuucaa gaccaagcuc gacaaggaga ucugcgccga ccccacccag      240

aagugggucc aggacuucau gaagcaccuc gacaagaaga cccagacccc caagcucuga      300


<210>  350
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  350
augcuccuca cccucaucau ccuccucccc gucgucucca aguucuccuu cgucucccuc       60

uccgcccccc agcacugguc cugccccgag ggcacccucg ccggcaacgg caacuccacc      120

ugcgucggcc ccgcccccuu ccucaucuuc ucccacggca acuccaucuu ccgcaucgac      180

accgagggca ccaacuacga gcagcucguc gucgacgccg gcgucuccgu caucauggac      240

uuccacuaca acgagaagcg caucuacugg gucgaccucg agcgccagcu ccuccagcgc      300

gucuuccuca acggcucccg ccaggagcgc gucugcaaca ucgagaagaa cgucuccggc      360

auggccauca acuggaucaa cgaggagguc aucuggucca accagcagga gggcaucauc      420

accgucaccg acaugaaggg caacaacucc cacauccucc ucuccgcccu caaguacccc      480

gccaacgucg ccgucgaccc cgucgagcgc uucaucuucu gguccuccga ggucgccggc      540

ucccucuacc gcgccgaccu cgacggcguc ggcgucaagg cccuccucga gaccuccgag      600

aagaucaccg ccgucucccu cgacguccuc gacaagcgcc ucuucuggau ccaguacaac      660

cgcgagggcu ccaacucccu caucugcucc ugcgacuacg acggcggcuc cguccacauc      720

uccaagcacc ccacccagca caaccucuuc gccauguccc ucuucggcga ccgcaucuuc      780

uacuccaccu ggaagaugaa gaccaucugg aucgccaaca agcacaccgg caaggacaug      840

guccgcauca accuccacuc cuccuucguc ccccucggcg agcucaaggu cguccacccc      900

cucgcccagc ccaaggccga ggacgacacc ugggagcccg agcagaagcu cugcaagcuc      960

cgcaagggca acugcuccuc caccgucugc ggccaggacc uccaguccca ccucugcaug     1020

ugcgccgagg gcuacgcccu cucccgcgac cgcaaguacu gcgaggacgu caacgagugc     1080

gccuucugga accacggcug cacccucggc ugcaagaaca cccccggcuc cuacuacugc     1140

accugccccg ucggcuucgu ccuccucccc gacggcaagc gcugccacca gcucgucucc     1200

ugcccccgca acgucuccga gugcucccac gacugcgucc ucaccuccga gggcccccuc     1260

ugcuucugcc ccgagggcuc cguccucgag cgcgacggca agaccugcuc cggcugcucc     1320

ucccccgaca acggcggcug cucccagcuc ugcguccccc ucucccccgu cuccugggag     1380

ugcgacugcu uccccggcua cgaccuccag cucgacgaga aguccugcgc cgccuccggc     1440

ccccagcccu uccuccucuu cgccaacucc caggacaucc gccacaugca cuucgacggc     1500

accgacuacg gcacccuccu cucccagcag augggcaugg ucuacgcccu cgaccacgac     1560

cccgucgaga acaagaucua cuucgcccac accgcccuca aguggaucga gcgcgccaac     1620

auggacggcu cccagcgcga gcgccucauc gaggagggcg ucgacguccc cgagggccuc     1680

gccgucgacu ggaucggccg ccgcuucuac uggaccgacc gcggcaaguc ccucaucggc     1740

cgcuccgacc ucaacggcaa gcgcuccaag aucaucacca aggagaacau cucccagccc     1800

cgcggcaucg ccguccaccc cauggccaag cgccucuucu ggaccgacac cggcaucaac     1860

ccccgcaucg aguccuccuc ccuccagggc cucggccgcc ucgucaucgc cuccuccgac     1920

cucaucuggc ccuccggcau caccaucgac uuccucaccg acaagcucua cuggugcgac     1980

gccaagcagu ccgucaucga gauggccaac cucgacggcu ccaagcgccg ccgccucacc     2040

cagaacgacg ucggccaccc cuucgccguc gccgucuucg aggacuacgu cugguucucc     2100

gacugggcca ugcccuccgu caugcgcguc aacaagcgca ccggcaagga ccgcguccgc     2160

cuccagggcu ccaugcucaa gcccuccucc cucgucgucg uccacccccu cgccaagccc     2220

ggcgccgacc ccugccucua ccagaacggc ggcugcgagc acaucugcaa gaagcgccuc     2280

ggcaccgccu ggugcuccug ccgcgagggc uucaugaagg ccuccgacgg caagaccugc     2340

cucgcccucg acggccacca gcuccucgcc ggcggcgagg ucgaccucaa gaaccagguc     2400

accccccucg acauccucuc caagacccgc gucuccgagg acaacaucac cgagucccag     2460

cacaugcucg ucgccgagau cauggucucc gaccaggacg acugcgcccc cgucggcugc     2520

uccauguacg cccgcugcau cuccgagggc gaggacgcca ccugccagug ccucaagggc     2580

uucgccggcg acggcaagcu cugcuccgac aucgacgagu gcgagauggg cguccccguc     2640

ugcccccccg ccuccuccaa gugcaucaac accgagggcg gcuacgucug ccgcugcucc     2700

gagggcuacc agggcgacgg cauccacugc cucgacaucg acgagugcca gcucggcgag     2760

cacuccugcg gcgagaacgc cuccugcacc aacaccgagg gcggcuacac cugcaugugc     2820

gccggccgcc ucuccgagcc cggccucauc ugccccgacu ccaccccccc cccccaccuc     2880

cgcgaggacg accaccacua cuccguccgc aacuccgacu ccgagugccc ccucucccac     2940

gacggcuacu gccuccacga cggcgucugc auguacaucg aggcccucga caaguacgcc     3000

ugcaacugcg ucgucggcua caucggcgag cgcugccagu accgcgaccu caaguggugg     3060

gagcuccgcc acgccggcca cggccagcag cagaagguca ucgucgucgc cgucugcguc     3120

gucguccucg ucaugcuccu ccuccucucc cucuggggcg cccacuacua ccgcacccag     3180

aagcuccucu ccaagaaccc caagaacccc uacgaggagu ccucccgcga cguccgcucc     3240

cgccgccccg ccgacaccga ggacggcaug uccuccugcc cccagcccug guucgucguc     3300

aucaaggagc accaggaccu caagaacggc ggccagcccg ucgccggcga ggacggccag     3360

gccgccgacg gcuccaugca gcccaccucc uggcgccagg agccccagcu cugcggcaug     3420

ggcaccgagc agggcugcug gauccccguc uccuccgaca agggcuccug cccccagguc     3480

auggagcgcu ccuuccacau gcccuccuac ggcacccaga cccucgaggg cggcgucgag     3540

aagccccacu cccuccucuc cgccaacccc cucuggcagc agcgcgcccu cgaccccccc     3600

caccagaugg agcucaccca guga                                            3624


<210>  351
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  351
augaccgccg gccgccgcau ggagaugcuc ugcgccggcc gcguccccgc ccuccuccuc       60

ugccucggcu uccaccuccu ccaggccguc cucuccacca ccgucauccc cuccugcauc      120

cccggcgagu ccuccgacaa cugcaccgcc cucguccaga ccgaggacaa cccccgcguc      180

gcccaggucu ccaucaccaa gugcuccucc gacaugaacg gcuacugccu ccacggccag      240

ugcaucuacc ucgucgacau gucccagaac uacugccgcu gcgaggucgg cuacaccggc      300

guccgcugcg agcacuucuu ccucaccguc caccagcccc ucuccaagga guacgucgcc      360

cucaccguca uccucaucau ccucuuccuc aucaccgucg ucggcuccac cuacuacuuc      420

ugccgcuggu accgcaaccg caaguccaag gagcccaaga aggaguacga gcgcgucacc      480

uccggcgacc ccgagcuccc ccaggucuga                                       510


<210>  352
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  352
auggccgagg gcgagaucac caccuucacc gcccucaccg agaaguucaa ccuccccccc       60

ggcaacuaca agaagcccaa gcuccucuac ugcuccaacg gcggccacuu ccuccgcauc      120

cuccccgacg gcaccgucga cggcacccgc gaccgcuccg accagcacau ccagcuccag      180

cucuccgccg aguccgucgg cgaggucuac aucaagucca ccgagaccgg ccaguaccuc      240

gccauggaca ccgacggccu ccucuacggc ucccagaccc ccaacgagga gugccucuuc      300

cucgagcgcc ucgaggagaa ccacuacaac accuacaucu ccaagaagca cgccgagaag      360

aacugguucg ucggccucaa gaagaacggc uccugcaagc gcggcccccg cacccacuac      420

ggccagaagg ccauccucuu ccucccccuc cccgucuccu ccgacuga                   468


<210>  353
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  353
auggucggcg ucggcggcgg cgacgucgag gacgucaccc cccgccccgg cggcugccag       60

aucuccggcc gcggcgcccg cggcugcaac ggcauccccg gcgccgccgc cugggaggcc      120

gcccuccccc gccgccgccc ccgccgccac cccuccguca acccccgcuc ccgcgccgcc      180

ggcucccccc gcacccgcgg ccgccgcacc gaggagcgcc ccuccggcuc ccgccucggc      240

gaccgcggcc gcggccgcgc ccuccccggc ggccgccucg gcggccgcgg ccgcggccgc      300

gcccccgagc gcgucggcgg ccgcggccgc ggccgcggca ccgccgcccc ccgcgccgcc      360

cccgccgccc gcggcucccg ccccggcccc gccggcacca uggccgccgg cuccaucacc      420

acccuccccg cccuccccga ggacggcggc uccggcgccu ucccccccgg ccacuucaag      480

gaccccaagc gccucuacug caagaacggc ggcuucuucc uccgcaucca ccccgacggc      540

cgcgucgacg gcguccgcga gaaguccgac ccccacauca agcuccagcu ccaggccgag      600

gagcgcggcg ucgucuccau caagggcguc ugcgccaacc gcuaccucgc caugaaggag      660

gacggccgcc uccucgccuc caagugcguc accgacgagu gcuucuucuu cgagcgccuc      720

gaguccaaca acuacaacac cuaccgcucc cgcaaguaca ccuccuggua cgucgcccuc      780

aagcgcaccg gccaguacaa gcucggcucc aagaccggcc ccggccagaa ggccauccuc      840

uuccucccca uguccgccaa guccuga                                          867


<210>  354
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  354
augcacaagu ggauccucac cuggauccuc cccacccucc ucuaccgcuc cugcuuccac       60

aucaucugcc ucgucggcac caucucccuc gccugcaacg acaugacccc cgagcagaug      120

gccaccaacg ucaacugcuc cucccccgag cgccacaccc gcuccuacga cuacauggag      180

ggcggcgaca uccgcguccg ccgccucuuc ugccgcaccc agugguaccu ccgcaucgac      240

aagcgcggca aggucaaggg cacccaggag augaagaaca acuacaacau cauggagauc      300

cgcaccgucg ccgucggcau cgucgccauc aagggcgucg aguccgaguu cuaccucgcc      360

augaacaagg agggcaagcu cuacgccaag aaggagugca acgaggacug caacuucaag      420

gagcucaucc ucgagaacca cuacaacacc uacgccuccg ccaaguggac ccacaacggc      480

ggcgagaugu ucgucgcccu caaccagaag ggcauccccg uccgcggcaa gaagaccaag      540

aaggagcaga agaccgccca cuuccucccc auggccauca ccuga                      585


<210>  355
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  355
augaagcucc uccccuccgu cguccucaag cucuuccucg ccgccguccu cuccgcccuc       60

gucaccggcg agucccucga gcgccuccgc cgcggccucg ccgccggcac cuccaacccc      120

gaccccccca ccgucuccac cgaccagcuc cucccccucg gcggcggccg cgaccgcaag      180

guccgcgacc uccaggaggc cgaccucgac cuccuccgcg ucacccucuc cuccaagccc      240

caggcccucg ccacccccaa caaggaggag cacggcaagc gcaagaagaa gggcaagggc      300

cucggcaaga agcgcgaccc cugccuccgc aaguacaagg acuucugcau ccacggcgag      360

ugcaaguacg ucaaggagcu ccgcgccccc uccugcaucu gccaccccgg cuaccacggc      420

gagcgcugcc acggccucuc ccuccccguc gagaaccgcc ucuacaccua cgaccacacc      480

accauccucg ccgucgucgc cgucguccuc uccuccgucu gccuccucgu caucgucggc      540

cuccucaugu uccgcuacca ccgccgcggc ggcuacgacg ucgagaacga ggagaagguc      600

aagcucggca ugaccaacuc ccacuga                                          627


<210>  356
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  356
auguggguca ccaagcuccu ccccgcccuc cuccuccagc acguccuccu ccaccuccuc       60

cuccucccca ucgccauccc cuacgccgag ggccagcgca agcgccgcaa caccauccac      120

gaguucaaga aguccgccaa gaccacccuc aucaagaucg accccgcccu caagaucaag      180

accaagaagg ucaacaccgc cgaccagugc gccaaccgcu gcacccgcaa caagggccuc      240

cccuucaccu gcaaggccuu cgucuucgac aaggcccgca agcagugccu cugguucccc      300

uucaacucca uguccuccgg cgucaagaag gaguucggcc acgaguucga ccucuacgag      360

aacaaggacu acauccgcaa cugcaucauc ggcaagggcc gcuccuacaa gggcaccguc      420

uccaucacca aguccggcau caagugccag cccugguccu ccaugauccc ccacgagcac      480

uccuuccucc ccuccuccua ccgcggcaag gaccuccagg agaacuacug ccgcaacccc      540

cgcggcgagg agggcggccc cuggugcuuc accuccaacc ccgagguccg cuacgagguc      600

ugcgacaucc cccagugcuc cgaggucgag ugcaugaccu gcaacggcga guccuaccgc      660

ggccucaugg accacaccga guccggcaag aucugccagc gcugggacca ccagaccccc      720

caccgccaca aguuccuccc cgagcgcuac cccgacaagg gcuucgacga caacuacugc      780

cgcaaccccg acggccagcc ccgccccugg ugcuacaccc ucgaccccca cacccgcugg      840

gaguacugcg ccaucaagac cugcgccgac aacaccauga acgacaccga cgucccccuc      900

gagaccaccg agugcaucca gggccagggc gagggcuacc gcggcaccgu caacaccauc      960

uggaacggca uccccugcca gcgcugggac ucccaguacc cccacgagca cgacaugacc     1020

cccgagaacu ucaagugcaa ggaccuccgc gagaacuacu gccgcaaccc cgacggcucc     1080

gagucccccu ggugcuucac caccgacccc aacauccgcg ucggcuacug cucccagauc     1140

cccaacugcg acauguccca cggccaggac ugcuaccgcg gcaacggcaa gaacuacaug     1200

ggcaaccucu cccagacccg cuccggccuc accugcucca ugugggacaa gaacauggag     1260

gaccuccacc gccacaucuu cugggagccc gacgccucca agcucaacga gaacuacugc     1320

cgcaaccccg acgacgacgc ccacggcccc uggugcuaca ccggcaaccc ccucaucccc     1380

ugggacuacu gccccaucuc ccgcugcgag ggcgacacca cccccaccau cgucaaccuc     1440

gaccaccccg ucaucuccug cgccaagacc aagcagcucc gcgucgucaa cggcaucccc     1500

acccgcacca acaucggcug gauggucucc cuccgcuacc gcaacaagca caucugcggc     1560

ggcucccuca ucaaggaguc cuggguccuc accgcccgcc agugcuuccc cucccgcgac     1620

cucaaggacu acgaggccug gcucggcauc cacgacgucc acggccgcgg cgacgagaag     1680

ugcaagcagg uccucaacgu cucccagcuc gucuacggcc ccgagggcuc cgaccucguc     1740

cucaugaagc ucgcccgccc cgccguccuc gacgacuucg ucuccaccau cgaccucccc     1800

aacuacggcu gcaccauccc cgagaagacc uccugcuccg ucuacggcug gggcuacacc     1860

ggccucauca acuacgacgg ccuccuccgc gucgcccacc ucuacaucau gggcaacgag     1920

aagugcuccc agcaccaccg cggcaagguc acccucaacg aguccgagau cugcgccggc     1980

gccgagaaga ucggcuccgg ccccugcgag ggcgacuacg gcggcccccu cgucugcgag     2040

cagcacaaga ugcgcauggu ccucggcguc aucguccccg gccgcggcug cgccaucccc     2100

aaccgccccg gcaucuucgu ccgcgucgcc uacuacgcca aguggaucca caagaucauc     2160

cucaccuaca agguccccca guccuga                                         2187


<210>  357
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  357
auggccaagg ccgccgccau cggcaucgac cucggcacca ccuacuccug cgucggcguc       60

uuccagcacg gcaaggucga gaucaucgcc aacgaccagg gcaaccgcac cacccccucc      120

uacgucgccu ucaccgacac cgagcgccuc aucggcgacg ccgccaagaa ccaggucgcc      180

cucaaccccc agaacaccgu cuucgacgcc aagcgccuca ucggccgcaa guucggcgac      240

cccgucgucc aguccgacau gaagcacugg cccuuccagg ucaucaacga cggcgacaag      300

cccaaggucc aggucuccua caagggcgag accaaggccu ucuaccccga ggagaucucc      360

uccauggucc ucaccaagau gaaggagauc gccgaggccu accucggcua ccccgucacc      420

aacgccguca ucaccguccc cgccuacuuc aacgacuccc agcgccaggc caccaaggac      480

gccggcguca ucgccggccu caacguccuc cgcaucauca acgagcccac cgccgccgcc      540

aucgccuacg gccucgaccg caccggcaag ggcgagcgca acguccucau cuucgaccuc      600

ggcggcggca ccuucgacgu cuccauccuc accaucgacg acggcaucuu cgaggucaag      660

gccaccgccg gcgacaccca ccucggcggc gaggacuucg acaaccgccu cgucaaccac      720

uucgucgagg aguucaagcg caagcacaag aaggacaucu cccagaacaa gcgcgccguc      780

cgccgccucc gcaccgccug cgagcgcgcc aagcgcaccc ucuccuccuc cacccaggcc      840

ucccucgaga ucgacucccu cuucgagggc aucgacuucu acaccuccau cacccgcgcc      900

cgcuucgagg agcucugcuc cgaccucuuc cgcuccaccc ucgagcccgu cgagaaggcc      960

cuccgcgacg ccaagcucga caaggcccag auccacgacc ucguccucgu cggcggcucc     1020

acccgcaucc ccaaggucca gaagcuccuc caggacuucu ucaacggccg cgaccucaac     1080

aaguccauca accccgacga ggccgucgcc uacggcgccg ccguccaggc cgccauccuc     1140

augggcgaca aguccgagaa cguccaggac cuccuccucc ucgacgucgc cccccucucc     1200

cucggccucg agaccgccgg cggcgucaug accgcccuca ucaagcgcaa cuccaccauc     1260

cccaccaagc agacccagau cuucaccacc uacuccgaca accagcccgg cguccucauc     1320

caggucuacg agggcgagcg cgccaugacc aaggacaaca accuccucgg ccgcuucgag     1380

cucuccggca ucccccccgc cccccgcggc gucccccaga ucgaggucac cuucgacauc     1440

gacgccaacg gcauccucaa cgucaccgcc accgacaagu ccaccggcaa ggccaacaag     1500

aucaccauca ccaacgacaa gggccgccuc uccaaggagg agaucgagcg caugguccag     1560

gaggccgaga aguacaaggc cgaggacgag guccagcgcg agcgcgucuc cgccaagaac     1620

gcccucgagu ccuacgccuu caacaugaag uccgccgucg aggacgaggg ccucaagggc     1680

aagaucuccg aggccgacaa gaagaagguc cucgacaagu gccaggaggu caucuccugg     1740

cucgacgcca acacccucgc cgagaaggac gaguucgagc acaagcgcaa ggagcucgag     1800

caggucugca accccaucau cuccggccuc uaccagggcg ccggcggccc cggccccggc     1860

ggcuucggcg cccagggccc caagggcggc uccggcuccg gccccaccau cgaggagguc     1920

gacuga                                                                1926


<210>  358
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  358
auggccaagg ccgccgccau cggcaucgac cucggcacca ccuacuccug cgucggcguc       60

uuccagcacg gcaaggucga gaucaucgcc aacgaccagg gcaaccgcac cacccccucc      120

uacgucgccu ucaccgacac cgagcgccuc aucggcgacg ccgccaagaa ccaggucgcc      180

cucaaccccc agaacaccgu cuucgacgcc aagcgccuca ucggccgcaa guucggcgac      240

cccgucgucc aguccgacau gaagcacugg cccuuccagg ucaucaacga cggcgacaag      300

cccaaggucc aggucuccua caagggcgag accaaggccu ucuaccccga ggagaucucc      360

uccauggucc ucaccaagau gaaggagauc gccgaggccu accucggcua ccccgucacc      420

aacgccguca ucaccguccc cgccuacuuc aacgacuccc agcgccaggc caccaaggac      480

gccggcguca ucgccggccu caacguccuc cgcaucauca acgagcccac cgccgccgcc      540

aucgccuacg gccucgaccg caccggcaag ggcgagcgca acguccucau cuucgaccuc      600

ggcggcggca ccuucgacgu cuccauccuc accaucgacg acggcaucuu cgaggucaag      660

gccaccgccg gcgacaccca ccucggcggc gaggacuucg acaaccgccu cgucaaccac      720

uucgucgagg aguucaagcg caagcacaag aaggacaucu cccagaacaa gcgcgccguc      780

cgccgccucc gcaccgccug cgagcgcgcc aagcgcaccc ucuccuccuc cacccaggcc      840

ucccucgaga ucgacucccu cuucgagggc aucgacuucu acaccuccau cacccgcgcc      900

cgcuucgagg agcucugcuc cgaccucuuc cgcuccaccc ucgagcccgu cgagaaggcc      960

cuccgcgacg ccaagcucga caaggcccag auccacgacc ucguccucgu cggcggcucc     1020

acccgcaucc ccaaggucca gaagcuccuc caggacuucu ucaacggccg cgaccucaac     1080

aaguccauca accccgacga ggccgucgcc uacggcgccg ccguccaggc cgccauccuc     1140

augggcgaca aguccgagaa cguccaggac cuccuccucc ucgacgucgc cccccucucc     1200

cucggccucg agaccgccgg cggcgucaug accgcccuca ucaagcgcaa cuccaccauc     1260

cccaccaagc agacccagau cuucaccacc uacuccgaca accagcccgg cguccucauc     1320

caggucuacg agggcgagcg cgccaugacc aaggacaaca accuccucgg ccgcuucgag     1380

cucuccggca ucccccccgc cccccgcggc gucccccaga ucgaggucac cuucgacauc     1440

gacgccaacg gcauccucaa cgucaccgcc accgacaagu ccaccggcaa ggccaacaag     1500

aucaccauca ccaacgacaa gggccgccuc uccaaggagg agaucgagcg caugguccag     1560

gaggccgaga aguacaaggc cgaggacgag guccagcgcg agcgcgucuc cgccaagaac     1620

gcccucgagu ccuacgccuu caacaugaag uccgccgucg aggacgaggg ccucaagggc     1680

aagaucuccg aggccgacaa gaagaagguc cucgacaagu gccaggaggu caucuccugg     1740

cucgacgcca acacccucgc cgagaaggac gaguucgagc acaagcgcaa ggagcucgag     1800

caggucugca accccaucau cuccggccuc uaccagggcg ccggcggccc cggccccggc     1860

ggcuucggcg cccagggccc caagggcggc uccggcuccg gccccaccau cgaggagguc     1920

gacuga                                                                1926


<210>  359
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  359
auggccaccg ccaagggcau cgccaucggc aucgaccucg gcaccaccua cuccugcguc       60

ggcgucuucc agcacggcaa ggucgagauc aucgccaacg accagggcaa ccgcaccacc      120

cccuccuacg ucgccuucac cgacaccgag cgccucaucg gcgacgccgc caagaaccag      180

gucgccauga acccccagaa caccgucuuc gacgccaagc gccucaucgg ccgcaaguuc      240

aacgaccccg ucguccaggc cgacaugaag cucuggcccu uccaggucau caacgagggc      300

ggcaagccca agguccucgu cuccuacaag ggcgagaaca aggccuucua ccccgaggag      360

aucuccucca ugguccucac caagcucaag gagaccgccg aggccuuccu cggccacccc      420

gucaccaacg ccgucaucac cguccccgcc uacuucaacg acucccagcg ccaggccacc      480

aaggacgccg gcgucaucgc cggccucaac guccuccgca ucaucaacga gcccaccgcc      540

gccgccaucg ccuacggccu cgacaagggc ggccagggcg agcgccacgu ccucaucuuc      600

gaccucggcg gcggcaccuu cgacgucucc auccucacca ucgacgacgg caucuucgag      660

gucaaggcca ccgccggcga cacccaccuc ggcggcgagg acuucgacaa ccgccucguc      720

ucccacuucg ucgaggaguu caagcgcaag cacaagaagg acaucuccca gaacaagcgc      780

gccguccgcc gccuccgcac cgccugcgag cgcgccaagc gcacccucuc cuccuccacc      840

caggccaacc ucgagaucga cucccucuac gagggcaucg acuucuacac cuccaucacc      900

cgcgcccgcu ucgaggagcu cugcgccgac cucuuccgcg gcacccucga gcccgucgag      960

aaggcccucc gcgacgccaa gauggacaag gccaagaucc acgacaucgu ccucgucggc     1020

ggcuccaccc gcauccccaa gguccagcgc cuccuccagg acuacuucaa cggccgcgac     1080

cucaacaagu ccaucaaccc cgacgaggcc gucgccuacg gcgccgccgu ccaggccgcc     1140

auccucaugg gcgacaaguc cgagaagguc caggaccucc uccuccucga cgucgccccc     1200

cucucccucg gccucgagac cgccggcggc gucaugaccg cccucaucaa gcgcaacucc     1260

accaucccca ccaagcagac ccagaucuuc accaccuacu ccgacaacca gcccggcguc     1320

cucauccagg ucuacgaggg cgagcgcgcc augaccaagg acaacaaccu ccucggccgc     1380

uucgaccuca ccggcauccc ccccgccccc cgcggcgucc cccagaucga ggucaccuuc     1440

gacaucgacg ccaacggcau ccucaacguc accgccaccg acaaguccac cggcaagguc     1500

aacaagauca ccaucaccaa cgacaagggc cgccucucca aggaggagau cgagcgcaug     1560

guccucgacg ccgagaagua caaggccgag gacgaggucc agcgcgagaa gaucgccgcc     1620

aagaacgccc ucgaguccua cgccuucaac augaaguccg ucgucuccga cgagggccuc     1680

aagggcaaga ucuccgaguc cgacaagaac aagauccucg acaagugcaa cgagcuccuc     1740

uccuggcucg aggucaacca gcucgccgag aaggacgagu ucgaccacaa gcgcaaggag     1800

cucgagcaga ugugcaaccc caucaucacc aagcucuacc agggcggcug caccggcccc     1860

gccugcggca ccggcuacgu ccccggccgc cccgccaccg gccccaccau cgaggagguc     1920

gacuga                                                                1926


<210>  360
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  360
auguccgccc gcggccccgc caucggcauc gaccucggca ccaccuacuc cugcgucggc       60

gucuuccagc acggcaaggu cgagaucauc gccaacgacc agggcaaccg caccaccccc      120

uccuacgucg ccuucaccga caccgagcgc cucaucggcg acgccgccaa gaaccagguc      180

gccaugaacc ccaccaacac caucuucgac gccaagcgcc ucaucggccg caaguucgag      240

gacgccaccg uccaguccga caugaagcac uggcccuucc gcgucgucuc cgagggcggc      300

aagcccaagg uccaggucga guacaagggc gagaccaaga ccuucuuccc cgaggagauc      360

uccuccaugg uccucaccaa gaugaaggag aucgccgagg ccuaccucgg cggcaagguc      420

cacuccgccg ucaucaccgu ccccgccuac uucaacgacu cccagcgcca ggccaccaag      480

gacgccggca ccaucaccgg ccucaacguc cuccgcauca ucaacgagcc caccgccgcc      540

gccaucgccu acggccucga caagaagggc ugcgccggcg gcgagaagaa cguccucauc      600

uucgaccucg gcggcggcac cuucgacguc uccauccuca ccaucgagga cggcaucuuc      660

gaggucaagu ccaccgccgg cgacacccac cucggcggcg aggacuucga caaccgcaug      720

gucucccacc ucgccgagga guucaagcgc aagcacaaga aggacaucgg ccccaacaag      780

cgcgccgucc gccgccuccg caccgccugc gagcgcgcca agcgcacccu cuccuccucc      840

acccaggccu ccaucgagau cgacucccuc uacgagggcg ucgacuucua caccuccauc      900

acccgcgccc gcuucgagga gcucaacgcc gaccucuucc gcggcacccu cgagcccguc      960

gagaaggccc uccgcgacgc caagcucgac aagggccaga uccaggagau cguccucguc     1020

ggcggcucca cccgcauccc caagauccag aagcuccucc aggacuucuu caacggcaag     1080

gagcucaaca aguccaucaa ccccgacgag gccgucgccu acggcgccgc cguccaggcc     1140

gccauccuca ucggcgacaa guccgagaac guccaggacc uccuccuccu cgacgucacc     1200

ccccucuccc ucggcaucga gaccgccggc ggcgucauga ccccccucau caagcgcaac     1260

accaccaucc ccaccaagca gacccagacc uucaccaccu acuccgacaa ccaguccucc     1320

guccucgucc aggucuacga gggcgagcgc gccaugacca aggacaacaa ccuccucggc     1380

aaguucgacc ucaccggcau cccccccgcc ccccgcggcg ucccccagau cgaggucacc     1440

uucgacaucg acgccaacgg cauccucaac gucaccgccg ccgacaaguc caccggcaag     1500

gagaacaaga ucaccaucac caacgacaag ggccgccucu ccaaggacga caucgaccgc     1560

augguccagg aggccgagcg cuacaagucc gaggacgagg ccaaccgcga ccgcgucgcc     1620

gccaagaacg cccucgaguc cuacaccuac aacaucaagc agaccgucga ggacgagaag     1680

cuccgcggca agaucuccga gcaggacaag aacaagaucc ucgacaagug ccaggagguc     1740

aucaacuggc ucgaccgcaa ccagauggcc gagaaggacg aguacgagca caagcagaag     1800

gagcucgagc gcgucugcaa ccccaucauc uccaagcucu accagggcgg ccccggcggc     1860

ggcuccggcg gcggcggcuc cggcgccucc ggcggcccca ccaucgagga ggucgacuga     1920


<210>  361
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  361
auguccgucg ucggcaucga ccucggcuuc caguccugcu acgucgccgu cgcccgcgcc       60

ggcggcaucg agaccaucgc caacgaguac uccgaccgcu gcacccccgc cugcaucucc      120

uucggcccca agaaccgcuc caucggcgcc gccgccaagu cccaggucau cuccaacgcc      180

aagaacaccg uccagggcuu caagcgcuuc cacggccgcg ccuucuccga ccccuucguc      240

gaggccgaga aguccaaccu cgccuacgac aucguccagc uccccaccgg ccucaccggc      300

aucaagguca ccuacaugga ggaggagcgc aacuucacca ccgagcaggu caccgccaug      360

cuccucucca agcucaagga gaccgccgag uccguccuca agaagcccgu cgucgacugc      420

gucgucuccg uccccugcuu cuacaccgac gccgagcgcc gcuccgucau ggacgccacc      480

cagaucgccg gccucaacug ccuccgccuc augaacgaga ccaccgccgu cgcccucgcc      540

uacggcaucu acaagcagga ccuccccgcc cucgaggaga agccccgcaa cgucgucuuc      600

gucgacaugg gccacuccgc cuaccagguc uccgucugcg ccuucaaccg cggcaagcuc      660

aagguccucg ccaccgccuu cgacaccacc cucggcggcc gcaaguucga cgagguccuc      720

gucaaccacu ucugcgagga guucggcaag aaguacaagc ucgacaucaa guccaagauc      780

cgcgcccucc uccgccucuc ccaggagugc gagaagcuca agaagcucau guccgccaac      840

gccuccgacc ucccccucuc caucgagugc uucaugaacg acgucgacgu cuccggcacc      900

augaaccgcg gcaaguuccu cgagaugugc aacgaccucc ucgcccgcgu cgagcccccc      960

cuccgcuccg uccucgagca gaccaagcuc aagaaggagg acaucuacgc cgucgagauc     1020

gucggcggcg ccacccgcau ccccgccguc aaggagaaga ucuccaaguu cuucggcaag     1080

gagcucucca ccacccucaa cgccgacgag gccgucaccc gcggcugcgc ccuccagugc     1140

gccauccucu cccccgccuu caagguccgc gaguucucca ucaccgacgu cguccccuac     1200

cccaucuccc uccgcuggaa cucccccgcc gaggagggcu ccuccgacug cgaggucuuc     1260

uccaagaacc acgccgcccc cuucuccaag guccucaccu ucuaccgcaa ggagcccuuc     1320

acccucgagg ccuacuacuc cuccccccag gaccuccccu accccgaccc cgccaucgcc     1380

caguucuccg uccagaaggu caccccccag uccgacggcu ccuccuccaa ggucaagguc     1440

aagguccgcg ucaacgucca cggcaucuuc uccgucuccu ccgccucccu cgucgagguc     1500

cacaaguccg aggagaacga ggagcccaug gagaccgacc agaacgccaa ggaggaggag     1560

aagaugcagg ucgaccagga ggagccccac gucgaggagc agcagcagca gacccccgcc     1620

gagaacaagg ccgaguccga ggagauggag accucccagg ccggcuccaa ggacaagaag     1680

auggaccagc ccccccaggc caagaaggcc aaggucaaga ccuccaccgu cgaccucccc     1740

aucgagaacc agcuccucug gcagaucgac cgcgagaugc ucaaccucua caucgagaac     1800

gagggcaaga ugaucaugca ggacaagcuc gagaaggagc gcaacgacgc caagaacgcc     1860

gucgaggagu acgucuacga gaugcgcgac aagcucuccg gcgaguacga gaaguucguc     1920

uccgaggacg accgcaacuc cuucacccuc aagcucgagg acaccgagaa cuggcucuac     1980

gaggacggcg aggaccagcc caagcagguc uacgucgaca agcucgccga gcucaagaac     2040

cucggccagc ccaucaagau ccgcuuccag gaguccgagg agcgccccaa gcucuucgag     2100

gagcucggca agcagaucca gcaguacaug aagaucaucu ccuccuucaa gaacaaggag     2160

gaccaguacg accaccucga cgccgccgac augaccaagg ucgagaaguc caccaacgag     2220

gccauggagu ggaugaacaa caagcucaac cuccagaaca agcagucccu caccauggac     2280

cccgucguca aguccaagga gaucgaggcc aagaucaagg agcucaccuc caccugcucc     2340

cccaucaucu ccaagcccaa gcccaagguc gagcccccca aggaggagca gaagaacgcc     2400

gagcagaacg gccccgucga cggccagggc gacaaccccg gcccccaggc cgccgagcag     2460

ggcaccgaca ccgccguccc cuccgacucc gacaagaagc uccccgagau ggacaucgac     2520

uga                                                                   2523


<210>  362
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  362
auguccgucg ucggcaucga ccucggcuuc cucaacugcu acaucgccgu cgcccgcucc       60

ggcggcaucg agaccaucgc caacgaguac uccgaccgcu gcacccccgc cugcaucucc      120

cucggcuccc gcacccgcgc caucggcaac gccgccaagu cccagaucgu caccaacguc      180

cgcaacacca uccacggcuu caagaagcuc cacggccgcu ccuucgacga ccccaucguc      240

cagaccgagc gcauccgccu ccccuacgag cuccagaaga ugcccaacgg cuccgccggc      300

gucaaggucc gcuaccucga ggaggagcgc cccuucgcca ucgagcaggu caccggcaug      360

cuccucgcca agcucaagga gaccuccgag aacgcccuca agaagcccgu cgccgacugc      420

gucaucucca uccccuccuu cuucaccgac gccgagcgcc gcuccgucau ggccgccgcc      480

caggucgccg gccucaacug ccuccgccuc augaacgaga ccaccgccgu cgcccucgcc      540

uacggcaucu acaagcagga ccuccccccc cucgacgaga agccccgcaa cgucgucuuc      600

aucgacaugg gccacuccgc cuaccagguc cucgucugcg ccuucaacaa gggcaagcuc      660

aagguccucg ccaccaccuu cgaccccuac cucggcggcc gcaacuucga cgaggcccuc      720

gucgacuacu ucugcgacga guucaagacc aaguacaaga ucaacgucaa ggagaacucc      780

cgcgcccucc uccgccucua ccaggagugc gagaagcuca agaagcucau guccgccaac      840

gccuccgacc ucccccucaa caucgagugc uucaugaacg accucgacgu cuccuccaag      900

augaaccgcg cccaguucga gcagcucugc gccucccucc ucgcccgcgu cgagcccccc      960

cucaaggccg ucauggagca ggccaaccuc cagcgcgagg acaucuccuc caucgagauc     1020

gucggcggcg ccacccgcau ccccgccguc aaggagcaga ucaccaaguu cuuccucaag     1080

gacaucucca ccacccucaa cgccgacgag gccgucgccc gcggcugcgc ccuccagugc     1140

gccauccucu cccccgccuu caagguccgc gaguucucca ucaccgaccu cguccccuac     1200

uccaucaccc uccgcuggaa gaccuccuuc gaggacggcu ccggcgagug cgaggucuuc     1260

ugcaagaacc accccgcccc cuucuccaag gucaucaccu uccacaagaa ggagcccuuc     1320

gagcucgagg ccuucuacac caaccuccac gagguccccu accccgacgc ccgcaucggc     1380

uccuucacca uccagaacgu cuucccccag uccgacggcg acuccuccaa ggucaagguc     1440

aagguccgcg ucaacaucca cggcaucuuc uccgucgccu ccgccuccgu caucgagaag     1500

cagaaccucg agggcgacca cuccgacgcc cccauggaga ccgagaccuc cuucaagaac     1560

gagaacaagg acaacaugga caagaugcag gucgaccagg aggagggcca ccagaagugc     1620

cacgccgagc acacccccga ggaggagauc gaccacaccg gcgccaagac caaguccgcc     1680

gucuccgaca agcaggaccg ccucaaccag acccucaaga agggcaaggu caaguccauc     1740

gaccucccca uccaguccuc ccucugccgc cagcucggcc aggaccuccu caacuccuac     1800

aucgagaacg agggcaagau gaucaugcag gacaagcucg agaaggagcg caacgacgcc     1860

aagaacgccg ucgaggagua cgucuacgac uuccgcgacc gccucggcac cgucuacgag     1920

aaguucauca cccccgagga ccucuccaag cucuccgccg uccucgagga caccgagaac     1980

uggcucuacg aggacggcga ggaccagccc aagcaggucu acgucgacaa gcuccaggag     2040

cucaagaagu acggccagcc cauccagaug aaguacaugg agcacgagga gcgccccaag     2100

gcccucaacg accucggcaa gaagauccag cucgucauga aggucaucga ggccuaccgc     2160

aacaaggacg agcgcuacga ccaccucgac cccaccgaga uggagaaggu cgagaagugc     2220

aucuccgacg ccauguccug gcucaacucc aagaugaacg cccagaacaa gcucucccuc     2280

acccaggacc ccgucgucaa ggucuccgag aucgucgcca aguccaagga gcucgacaac     2340

uucugcaacc ccaucaucua caagcccaag cccaaggccg agguccccga ggacaagccc     2400

aaggccaacu ccgagcacaa cggccccaug gacggccagu ccggcaccga gaccaagucc     2460

gacuccacca aggacuccuc ccagcacacc aaguccuccg gcgagaugga ggucgacuga     2520


<210>  363
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  363
augaagcucu cccucgucgc cgccaugcuc cuccuccucu ccgccgcccg cgccgaggag       60

gaggacaaga aggaggacgu cggcaccguc gucggcaucg accucggcac caccuacucc      120

ugcgucggcg ucuucaagaa cggccgcguc gagaucaucg ccaacgacca gggcaaccgc      180

aucacccccu ccuacgucgc cuucaccccc gagggcgagc gccucaucgg cgacgccgcc      240

aagaaccagc ucaccuccaa ccccgagaac accgucuucg acgccaagcg ccucaucggc      300

cgcaccugga acgaccccuc cguccagcag gacaucaagu uccuccccuu caaggucguc      360

gagaagaaga ccaagcccua cauccagguc gacaucggcg gcggccagac caagaccuuc      420

gcccccgagg agaucuccgc caugguccuc accaagauga aggagaccgc cgaggccuac      480

cucggcaaga aggucaccca cgccgucguc accguccccg ccuacuucaa cgacgcccag      540

cgccaggcca ccaaggacgc cggcaccauc gccggccuca acgucaugcg caucaucaac      600

gagcccaccg ccgccgccau cgccuacggc cucgacaagc gcgagggcga gaagaacauc      660

cucgucuucg accucggcgg cggcaccuuc gacgucuccc uccucaccau cgacaacggc      720

gucuucgagg ucgucgccac caacggcgac acccaccucg gcggcgagga cuucgaccag      780

cgcgucaugg agcacuucau caagcucuac aagaagaaga ccggcaagga cguccgcaag      840

gacaaccgcg ccguccagaa gcuccgccgc gaggucgaga aggccaagcg cgcccucucc      900

ucccagcacc aggcccgcau cgagaucgag uccuucuacg agggcgagga cuucuccgag      960

acccucaccc gcgccaaguu cgaggagcuc aacauggacc ucuuccgcuc caccaugaag     1020

cccguccaga agguccucga ggacuccgac cucaagaagu ccgacaucga cgagaucguc     1080

cucgucggcg gcuccacccg cauccccaag auccagcagc ucgucaagga guucuucaac     1140

ggcaaggagc ccucccgcgg caucaacccc gacgaggccg ucgccuacgg cgccgccguc     1200

caggccggcg uccucuccgg cgaccaggac accggcgacc ucguccuccu cgacgucugc     1260

ccccucaccc ucggcaucga gaccgucggc ggcgucauga ccaagcucau cccccgcaac     1320

accgucgucc ccaccaagaa gucccagauc uucuccaccg ccuccgacaa ccagcccacc     1380

gucaccauca aggucuacga gggcgagcgc ccccucacca aggacaacca ccuccucggc     1440

accuucgacc ucaccggcau cccccccgcc ccccgcggcg ucccccagau cgaggucacc     1500

uucgagaucg acgucaacgg cauccuccgc gucaccgccg aggacaaggg caccggcaac     1560

aagaacaaga ucaccaucac caacgaccag aaccgccuca cccccgagga gaucgagcgc     1620

auggucaacg acgccgagaa guucgccgag gaggacaaga agcucaagga gcgcaucgac     1680

acccgcaacg agcucgaguc cuacgccuac ucccucaaga accagaucgg cgacaaggag     1740

aagcucggcg gcaagcucuc cuccgaggac aaggagacca uggagaaggc cgucgaggag     1800

aagaucgagu ggcucgaguc ccaccaggac gccgacaucg aggacuucaa ggccaagaag     1860

aaggagcucg aggagaucgu ccagcccauc aucuccaagc ucuacggcuc cgccggcccc     1920

ccccccaccg gcgaggagga caccgccgag aaggacgagc ucuga                     1965


<210>  364
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  364
augcaggccc cccgcgagcu cgccgucggc aucgaccucg gcaccaccua cuccugcguc       60

ggcgucuucc agcagggccg cgucgagauc cucgccaacg accagggcaa ccgcaccacc      120

cccuccuacg ucgccuucac cgacaccgag cgccucgucg gcgacgccgc caagucccag      180

gccgcccuca acccccacaa caccgucuuc gacgccaagc gccucaucgg ccgcaaguuc      240

gccgacacca ccguccaguc cgacaugaag cacuggcccu uccgcgucgu cuccgagggc      300

ggcaagccca agguccgcgu cugcuaccgc ggcgaggaca agaccuucua ccccgaggag      360

aucuccucca ugguccucuc caagaugaag gagaccgccg aggccuaccu cggccagccc      420

gucaagcacg ccgucaucac cguccccgcc uacuucaacg acucccagcg ccaggccacc      480

aaggacgccg gcgccaucgc cggccucaac guccuccgca ucaucaacga gcccaccgcc      540

gccgccaucg ccuacggccu cgaccgccgc ggcgccggcg agcgcaacgu ccucaucuuc      600

gaccucggcg gcggcaccuu cgacgucucc guccucucca ucgacgccgg cgucuucgag      660

gucaaggcca ccgccggcga cacccaccuc ggcggcgagg acuucgacaa ccgccucguc      720

aaccacuuca uggaggaguu ccgccgcaag cacggcaagg accucuccgg caacaagcgc      780

gcccuccgcc gccuccgcac cgccugcgag cgcgccaagc gcacccucuc cuccuccacc      840

caggccaccc ucgagaucga cucccucuuc gagggcgucg acuucuacac cuccaucacc      900

cgcgcccgcu ucgaggagcu cugcuccgac cucuuccgcu ccacccucga gcccgucgag      960

aaggcccucc gcgacgccaa gcucgacaag gcccagaucc acgacgucgu ccucgucggc     1020

ggcuccaccc gcauccccaa gguccagaag cuccuccagg acuucuucaa cggcaaggag     1080

cucaacaagu ccaucaaccc cgacgaggcc gucgccuacg gcgccgccgu ccaggccgcc     1140

guccucaugg gcgacaagug cgagaagguc caggaccucc uccuccucga cgucgccccc     1200

cucucccucg gccucgagac cgccggcggc gucaugacca cccucaucca gcgcaacgcc     1260

accaucccca ccaagcagac ccagaccuuc accaccuacu ccgacaacca gcccggcguc     1320

uucauccagg ucuacgaggg cgagcgcgcc augaccaagg acaacaaccu ccucggccgc     1380

uucgagcucu ccggcauccc ccccgccccc cgcggcgucc cccagaucga ggucaccuuc     1440

gacaucgacg ccaacggcau ccucuccguc accgccaccg accgcuccac cggcaaggcc     1500

aacaagauca ccaucaccaa cgacaagggc cgccucucca aggaggaggu cgagcgcaug     1560

guccacgagg ccgagcagua caaggccgag gacgaggccc agcgcgaccg cgucgccgcc     1620

aagaacuccc ucgaggccca cgucuuccac gucaagggcu cccuccagga ggagucccuc     1680

cgcgacaaga uccccgagga ggaccgccgc aagaugcagg acaagugccg cgagguccuc     1740

gccuggcucg agcacaacca gcucgccgag aaggaggagu acgagcacca gaagcgcgag     1800

cucgagcaga ucugccgccc caucuucucc cgccucuacg gcggccccgg cguccccggc     1860

ggcuccuccu gcggcaccca ggcccgccag ggcgaccccu ccaccggccc caucaucgag     1920

gaggucgacu ga                                                         1932


<210>  365
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__P48741__HsHSPA7

<400>  365
augcaggccc cccgcgagcu cgccgucggc aucgaccucg gcaccaccua cuccugcguc       60

ggcgucuucc agcagggccg cgucgagauc cucgccaacg accagggcaa ccgcaccacc      120

cccuccuacg ucgccuucac cgacaccgag cgccucgucg gcgacgccgc caagucccag      180

gccgcccuca acccccacaa caccgucuuc gacgccaagc gccucaucgg ccgcaaguuc      240

gccgacacca ccguccaguc cgacaugaag cacuggcccu uccaggucgu cuccgagggc      300

ggcaagccca agguccgcgu cugcuaccgc ggcgaggaca agaccuucua ccccgaggag      360

aucuccucca ugguccucuc caagaugaag gagaccgccg aggccuaccu cggccagccc      420

gucaagcacg ccgucaucac cguccccacc uacuucucca acucccagcg ccaggccacc      480

aaggacgccg gcgccaucgc cggccucaag guccucccca ucaucaacga ggccaccgcc      540

gccgccaucg ccuacggccu cgaccgccgc ggcgccggca agcgcaacgu ccucaucuuc      600

gaccucggcg gcggcaccuu cgacgucucc guccucucca ucgacgccgg cgucuucgag      660

gucaaggcca ccgccggcga cacccaccuc ggcggcgagg acuucgacaa ccgccucguc      720

aaccacuuca uggaggaguu ccgccgcaag cacggcaagg accucuccgg caacaagcgc      780

gcccuccgcc gccuccgcac cgccugcgag cgcgccaagc gcacccccuc cuccuccacc      840

caggccaccc ucgagaucga cucccucuuc gagggcgucg acuucuacaa guccaucacc      900

cgcgcccgcu ucgaggagcu cugcuccgac cucuuccgcu ccacccucga gcccgucgag      960

aaggcccucc gcgacgccaa gcucgacaag gcccagaucc acgacuucgu ccucggcggc     1020

ggccuccacu cccaccccca gggcgccgag gucgccgccg gccuccucca gcgccagggc     1080

gccgagcagg agcaccagcc cuga                                            1104


<210>  366
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  366
auguccaagg gccccgccgu cggcaucgac cucggcacca ccuacuccug cgucggcguc       60

uuccagcacg gcaaggucga gaucaucgcc aacgaccagg gcaaccgcac cacccccucc      120

uacgucgccu ucaccgacac cgagcgccuc aucggcgacg ccgccaagaa ccaggucgcc      180

augaacccca ccaacaccgu cuucgacgcc aagcgccuca ucggccgccg cuucgacgac      240

gccgucgucc aguccgacau gaagcacugg cccuucaugg ucgucaacga cgccggccgc      300

cccaaggucc aggucgagua caagggcgag accaaguccu ucuaccccga ggaggucucc      360

uccauggucc ucaccaagau gaaggagauc gccgaggccu accucggcaa gaccgucacc      420

aacgccgucg ucaccguccc cgccuacuuc aacgacuccc agcgccaggc caccaaggac      480

gccggcacca ucgccggccu caacguccuc cgcaucauca acgagcccac cgccgccgcc      540

aucgccuacg gccucgacaa gaaggucggc gccgagcgca acguccucau cuucgaccuc      600

ggcggcggca ccuucgacgu cuccauccuc accaucgagg acggcaucuu cgaggucaag      660

uccaccgccg gcgacaccca ccucggcggc gaggacuucg acaaccgcau ggucaaccac      720

uucaucgccg aguucaagcg caagcacaag aaggacaucu ccgagaacaa gcgcgccguc      780

cgccgccucc gcaccgccug cgagcgcgcc aagcgcaccc ucuccuccuc cacccaggcc      840

uccaucgaga ucgacucccu cuacgagggc aucgacuucu acaccuccau cacccgcgcc      900

cgcuucgagg agcucaacgc cgaccucuuc cgcggcaccc ucgaccccgu cgagaaggcc      960

cuccgcgacg ccaagcucga caagucccag auccacgaca ucguccucgu cggcggcucc     1020

acccgcaucc ccaagaucca gaagcuccuc caggacuucu ucaacggcaa ggagcucaac     1080

aaguccauca accccgacga ggccgucgcc uacggcgccg ccguccaggc cgccauccuc     1140

uccggcgaca aguccgagaa cguccaggac cuccuccucc ucgacgucac cccccucucc     1200

cucggcaucg agaccgccgg cggcgucaug accguccuca ucaagcgcaa caccaccauc     1260

cccaccaagc agacccagac cuucaccacc uacuccgaca accagcccgg cguccucauc     1320

caggucuacg agggcgagcg cgccaugacc aaggacaaca accuccucgg caaguucgag     1380

cucaccggca ucccccccgc cccccgcggc gucccccaga ucgaggucac cuucgacauc     1440

gacgccaacg gcauccucaa cgucuccgcc gucgacaagu ccaccggcaa ggagaacaag     1500

aucaccauca ccaacgacaa gggccgccuc uccaaggagg acaucgagcg caugguccag     1560

gaggccgaga aguacaaggc cgaggacgag aagcagcgcg acaaggucuc cuccaagaac     1620

ucccucgagu ccuacgccuu caacaugaag gccaccgucg aggacgagaa gcuccagggc     1680

aagaucaacg acgaggacaa gcagaagauc cucgacaagu gcaacgagau caucaacugg     1740

cucgacaaga accagaccgc cgagaaggag gaguucgagc accagcagaa ggagcucgag     1800

aaggucugca accccaucau caccaagcuc uaccaguccg ccggcggcau gcccggcggc     1860

augcccggcg gcuuccccgg cggcggcgcc ccccccuccg gcggcgccuc cuccggcccc     1920

accaucgagg aggucgacug a                                               1941


<210>  367
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  367
augaucuccg ccucccgcgc cgccgccgcc cgccucgucg gcgccgccgc cucccgcggc       60

cccaccgccg cccgccacca ggacuccugg aacggccucu cccacgaggc cuuccgccuc      120

gucucccgcc gcgacuacgc cuccgaggcc aucaagggcg ccgucgucgg caucgaccuc      180

ggcaccacca acuccugcgu cgccgucaug gagggcaagc aggccaaggu ccucgagaac      240

gccgagggcg cccgcaccac ccccuccguc gucgccuuca ccgccgacgg cgagcgccuc      300

gucggcaugc ccgccaagcg ccaggccguc accaacccca acaacaccuu cuacgccacc      360

aagcgccuca ucggccgccg cuacgacgac cccgaggucc agaaggacau caagaacguc      420

cccuucaaga ucguccgcgc cuccaacggc gacgccuggg ucgaggccca cggcaagcuc      480

uacucccccu cccagaucgg cgccuucguc cucaugaaga ugaaggagac cgccgagaac      540

uaccucggcc acaccgccaa gaacgccguc aucaccgucc ccgccuacuu caacgacucc      600

cagcgccagg ccaccaagga cgccggccag aucuccggcc ucaacguccu ccgcgucauc      660

aacgagccca ccgccgccgc ccucgccuac ggccucgaca aguccgagga caaggucauc      720

gccgucuacg accucggcgg cggcaccuuc gacaucucca uccucgagau ccagaagggc      780

gucuucgagg ucaaguccac caacggcgac accuuccucg gcggcgagga cuucgaccag      840

gcccuccucc gccacaucgu caaggaguuc aagcgcgaga ccggcgucga ccucaccaag      900

gacaacaugg cccuccagcg cguccgcgag gccgccgaga aggccaagug cgagcucucc      960

uccuccgucc agaccgacau caaccucccc uaccucacca uggacuccuc cggccccaag     1020

caccucaaca ugaagcucac ccgcgcccag uucgagggca ucgucaccga ccucauccgc     1080

cgcaccaucg cccccugcca gaaggccaug caggacgccg aggucuccaa guccgacauc     1140

ggcgagguca uccucgucgg cggcaugacc cgcaugccca agguccagca gaccguccag     1200

gaccucuucg gccgcgcccc cuccaaggcc gucaaccccg acgaggccgu cgccaucggc     1260

gccgccaucc agggcggcgu ccucgccggc gacgucaccg acguccuccu ccucgacguc     1320

accccccucu cccucggcau cgagacccuc ggcggcgucu ucaccaagcu caucaaccgc     1380

aacaccacca uccccaccaa gaagucccag gucuucucca ccgccgccga cggccagacc     1440

caggucgaga ucaaggucug ccagggcgag cgcgagaugg ccggcgacaa caagcuccuc     1500

ggccaguuca cccucaucgg cauccccccc gccccccgcg gcguccccca gaucgagguc     1560

accuucgaca ucgacgccaa cggcaucguc cacgucuccg ccaaggacaa gggcaccggc     1620

cgcgagcagc agaucgucau ccaguccucc ggcggccucu ccaaggacga caucgagaac     1680

auggucaaga acgccgagaa guacgccgag gaggaccgcc gcaagaagga gcgcgucgag     1740

gccgucaaca uggccgaggg caucauccac gacaccgaga ccaagaugga ggaguucaag     1800

gaccagcucc ccgccgacga gugcaacaag cucaaggagg agaucuccaa gaugcgcgag     1860

cuccucgccc gcaaggacuc cgagaccggc gagaacaucc gccaggccgc cuccucccuc     1920

cagcaggccu cccucaagcu cuucgagaug gccuacaaga agauggccuc cgagcgcgag     1980

ggcuccggcu ccuccggcac cggcgagcag aaggaggacc agaaggagga gaagcaguga     2040


<210>  368
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  368
auggccgaca aggaggccgg cggcuccgac ggcccccgcg agaccgcccc caccuccgcc       60

uacuccuccc ccgcccgcuc ccucggcgac accggcauca ccccccucuc ccccucccac      120

aucgucaacg acaccgacuc caacgucucc gagcagcagu ccuuccucgu cgucgucgcc      180

gucgacuucg gcaccaccuc cuccggcuac gccuacuccu ucaccaagga gcccgagugc      240

auccacguca ugcgccgcug ggagggcggc gaccccggcg ucuccaacca gaagaccccc      300

accaccaucc uccucacccc cgagcgcaag uuccacuccu ucggcuacgc cgcccgcgac      360

uucuaccacg accucgaccc caacgaggcc aagcaguggc ucuaccucga gaaguucaag      420

augaagcucc acaccaccgg cgaccucacc auggacaccg accucaccgc cgccaacggc      480

aagaagguca aggcccucga gaucuucgcc uacgcccucc aguacuucaa ggagcaggcc      540

cucaaggagc ucuccgacca ggccggcucc gaguucgaga acuccgacgu ccgcuggguc      600

aucaccgucc ccgccaucug gaagcagccc gccaagcagu ucaugcgcca ggccgccuac      660

caggccggcc ucgccucccc cgagaacucc gagcagcuca ucaucgcccu cgagcccgag      720

gccgccucca ucuacugccg caagcuccgc cuccaccaga ugaucgagcu cuccuccaag      780

gccgccguca acggcuacuc cggcuccgac accgucggcg ccggcuucac ccaggccaag      840

gagcacaucc gccgcaaccg ccagucccgc accuuccucg ucgagaacgu caucggcgag      900

aucugguccg agcucgagga gggcgacaag uacgucgucg ucgacuccgg cggcggcacc      960

gucgaccuca ccguccacca gauccgccuc cccgagggcc accucaagga gcucuacaag     1020

gccaccggcg gccccuacgg cucccucggc gucgacuacg aguucgagaa gcuccucuac     1080

aagaucuucg gcgaggacuu caucgagcag uucaagauca agcgccccgc cgccuggguc     1140

gaccucauga ucgccuucga gucccgcaag cgcgccgccg cccccgaccg caccaacccc     1200

cucaacauca cccuccccuu cuccuucauc gacuacuaca agaaguuccg cggccacucc     1260

gucgagcacg cccuccgcaa guccaacguc gacuucguca agugguccuc ccagggcaug     1320

cuccgcaugu cccccgacgc caugaacgcc cucuucaagc ccaccaucga cuccaucauc     1380

gagcaccucc gcgaccucuu ccagaagccc gaggucucca ccgucaaguu ccucuuccuc     1440

gucggcggcu ucgccgaggc cccccuccuc cagcaggccg uccaggccgc cuucggcgac     1500

cagugccgca ucaucauccc ccaggacguc ggccucacca uccucaaggg cgccguccuc     1560

uucggccucg accccgccgu caucaagguc cgccgcuccc cccucaccua cggcgucggc     1620

guccucaacc gcuacgucga gggcaagcac ccccccgaga agcuccucgu caaggacggc     1680

acccgcuggu gcaccgacgu cuucgacaag uucaucuccg ccgaccaguc cgucgcccuc     1740

ggcgagcucg ucaagcgcuc cuacaccccc gccaagcccu cccagcucgu caucgucauc     1800

aacaucuacu ccuccgagca cgacaacguc uccuucauca ccgaccccgg cgucaagaag     1860

ugcggcaccc uccgccucga ccucaccggc accuccggca ccgccguccc cgcccgccgc     1920

gagauccaga cccucaugca guucggcgac accgagauca aggccaccgc caucgacauc     1980

gccaccucca aguccgucaa ggucggcauc gacuuccuca acuacuga                  2028


<210>  369
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  369
augcucgccg uccccgagau gggccuccag ggccucuaca ucggcuccuc ccccgagcgc       60

ucccccgucc ccuccccccc cggcuccccc cgcacccagg aguccugcgg caucgccccc      120

cucacccccu cccagucccc caagcccgag guccgcgccc cccagcaggc cuccuucucc      180

gucgucgucg ccaucgacuu cggcaccacc uccuccggcu acgccuucuc cuucgccucc      240

gaccccgagg ccauccacau gaugcgcaag ugggagggcg gcgaccccgg cgucgcccac      300

cagaagaccc ccaccugccu ccuccucacc cccgagggcg ccuuccacuc cuucggcuac      360

accgcccgcg acuacuacca cgaccucgac cccgaggagg cccgcgacug gcucuacuuc      420

gagaaguuca agaugaagau ccacuccgcc accgaccuca cccucaagac ccagcucgag      480

gccgucaacg gcaagaccau gcccgcccuc gaggucuucg cccacgcccu ccgcuucuuc      540

cgcgagcacg cccuccagga gcuccgcgag cagucccccu cccuccccga gaaggacacc      600

guccgcuggg uccucaccgu ccccgccauc uggaagcagc ccgccaagca guucaugcgc      660

gaggccgccu accucgccgg ccucgucucc cgcgagaacg ccgagcagcu ccucaucgcc      720

cucgagcccg aggccgccuc cgucuacugc cgcaagcucc gccuccacca gcuccucgac      780

cucuccggcc gcgcccccgg cggcggccgc cucggcgagc gccgcuccau cgacuccucc      840

uuccgccagg cccgcgagca gcuccgccgc ucccgccacu cccgcaccuu ccucgucgag      900

uccggcgucg gcgagcucug ggccgagaug caggccggcg accgcuacgu cgucgccgac      960

ugcggcggcg gcaccgucga ccucaccguc caccagcucg agcagcccca cggcacccuc     1020

aaggagcucu acaaggccuc cggcggcccc uacggcgccg ucggcgucga ccucgccuuc     1080

gagcagcucc ucugccgcau cuucggcgag gacuucaucg ccaccuucaa gcgccagcgc     1140

cccgccgccu gggucgaccu caccaucgcc uucgaggccc gcaagcgcac cgccggcccc     1200

caccgcgccg gcgcccucaa caucucccuc cccuucuccu ucaucgacuu cuaccgcaag     1260

cagcgcggcc acaacgucga gaccgcccuc cgccgcuccu ccgucaacuu cgucaagugg     1320

uccucccagg gcaugcuccg cauguccugc gaggccauga acgagcucuu ccagcccacc     1380

gucuccggca ucauccagca caucgaggcc cuccucgccc gccccgaggu ccagggcguc     1440

aagcuccucu uccucgucgg cggcuucgcc gaguccgccg uccuccagca cgccguccag     1500

gccgcccucg gcgcccgcgg ccuccgcguc gucguccccc acgacgucgg ccucaccauc     1560

cucaagggcg ccguccucuu cggccaggcc cccggcgucg uccgcguccg ccgcuccccc     1620

cucaccuacg gcgucggcgu ccucaaccgc uucguccccg gccgccaccc ccccgagaag     1680

cuccucgucc gcgacggccg ccgcuggugc accgacgucu ucgagcgcuu cgucgccgcc     1740

gagcaguccg ucgcccucgg cgaggagguc cgccgcuccu acugccccgc ccgccccggc     1800

cagcgccgcg uccucaucaa ccucuacugc ugcgccgccg aggacgcccg cuucaucacc     1860

gaccccggcg uccgcaagug cggcgcccuc ucccucgagc ucgagcccgc cgacugcggc     1920

caggacaccg ccggcgcccc ccccggccgc cgcgagaucc gcgccgccau gcaguucggc     1980

gacaccgaga ucaaggucac cgccgucgac gucuccacca accgcuccgu ccgcgccucc     2040

aucgacuucc ucuccaacug a                                               2061


<210>  370
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  370
auggcccgcg agaugaccau ccucggcucc gccguccuca cccuccuccu cgccggcuac       60

cucgcccagc aguaccuccc ccuccccacc cccaagguca ucggcaucga ccucggcacc      120

accuacugcu ccgucggcgu cuucuucccc ggcaccggca aggucaaggu cauccccgac      180

gagaacggcc acaucuccau ccccuccaug gucuccuuca ccgacaacga cgucuacguc      240

ggcuacgagu ccgucgagcu cgccgacucc aacccccaga acaccaucua cgacgccaag      300

cgcuucaucg gcaagaucuu caccgccgag gagcucgagg ccgagaucgg ccgcuacccc      360

uucaaggucc ucaacaagaa cggcaugguc gaguucuccg ucaccuccaa cgagaccauc      420

accgucuccc ccgaguacgu cggcucccgc cuccuccuca agcucaagga gauggccgag      480

gccuaccucg gcaugcccgu cgccaacgcc gucaucuccg uccccgccga guucgaccuc      540

aagcagcgca acuccaccau cgaggccgcc aaccucgccg gccucaagau ccuccgcguc      600

aucaacgagc ccaccgccgc cgccauggcc uacggccucc acaaggccga cgucuuccac      660

guccucguca ucgaccucgg cggcggcacc cucgacgucu cccuccucaa caagcagggc      720

ggcauguucc ucacccgcgc cauguccggc aacaacaagc ucggcggcca ggacuucaac      780

cagcgccucc uccaguaccu cuacaagcag aucuaccaga ccuacggcuu cguccccucc      840

cgcaaggagg agauccaccg ccuccgccag gccgucgaga uggucaagcu caaccucacc      900

cuccaccagu ccgcccagcu cuccguccuc cucaccgucg aggagcagga ccgcaaggag      960

ccccacuccu ccgacaccga gcuccccaag gacaagcucu ccuccgccga cgaccaccgc     1020

gucaacuccg gcuucggccg cggccucucc gacaagaagu ccggcgaguc ccagguccuc     1080

uucgagaccg agaucucccg caagcucuuc gacacccuca acgaggaccu cuuccagaag     1140

auccucgucc ccauccagca gguccucaag gagggccacc ucgagaagac cgagaucgac     1200

gaggucgucc ucgucggcgg cuccacccgc aucccccgca uccgccaggu cauccaggag     1260

uucuucggca aggaccccaa caccuccguc gaccccgacc ucgccgucgu caccggcguc     1320

gccauccagg ccggcaucga cggcggcucc uggccccucc aggucuccgc ccucgagauc     1380

cccaacaagc accuccagaa gaccaacuuc aacuga                               1416


<210>  371
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  371
auggccgcca ucggcgucca ccucggcugc accuccgccu gcgucgccgu cuacaaggac       60

ggccgcgccg gcgucgucgc caacgacgcc ggcgaccgcg ucacccccgc cgucgucgcc      120

uacuccgaga acgaggagau cgucggccuc gccgccaagc agucccgcau ccgcaacauc      180

uccaacaccg ucaugaaggu caagcagauc cucggccgcu ccuccuccga cccccaggcc      240

cagaaguaca ucgccgaguc caagugccuc gucaucgaga agaacggcaa gcuccgcuac      300

gagaucgaca ccggcgagga gaccaaguuc gucaaccccg aggacgucgc ccgccucauc      360

uucuccaaga ugaaggagac cgcccacucc guccucggcu ccgacgccaa cgacgucguc      420

aucaccgucc ccuucgacuu cggcgagaag cagaagaacg cccucggcga ggccgcccgc      480

gccgccggcu ucaacguccu ccgccucauc cacgagcccu ccgccgcccu ccucgccuac      540

ggcaucggcc aggacucccc caccggcaag uccaacaucc ucgucuucaa gcucggcggc      600

accucccucu cccucuccgu cauggagguc aacuccggca ucuaccgcgu ccucuccacc      660

aacaccgacg acaacaucgg cggcgcccac uucaccgaga cccucgccca guaccucgcc      720

uccgaguucc agcgcuccuu caagcacgac guccgcggca acgcccgcgc caugaugaag      780

cucaccaacu ccgccgaggu cgccaagcac ucccucucca cccucggcuc cgccaacugc      840

uuccucgacu cccucuacga gggccaggac uucgacugca acgucucccg cgcccgcuuc      900

gagcuccucu gcuccccccu cuucaacaag ugcaucgagg ccauccgcgg ccuccucgac      960

cagaacggcu ucaccgccga cgacaucaac aaggucgucc ucugcggcgg cuccucccgc     1020

auccccaagc uccagcagcu caucaaggac cucuuccccg ccgucgagcu ccucaacucc     1080

aucccccccg acgaggucau ccccaucggc gccgccaucg aggccggcau ccucaucggc     1140

aaggagaacc uccucgucga ggacucccuc augaucgagu gcuccgcccg cgacauccuc     1200

gucaagggcg ucgacgaguc cggcgccucc cgcuucaccg uccucuuccc cuccggcacc     1260

ccccuccccg cccgccgcca gcacacccuc caggcccccg gcuccaucuc cuccgucugc     1320

cucgagcucu acgaguccga cggcaagaac uccgccaagg aggagaccaa guucgcccag     1380

gucguccucc aggaccucga caagaaggag aacggccucc gcgacauccu cgccguccuc     1440

accaugaagc gcgacggcuc ccuccacguc accugcaccg accaggagac cggcaagugc     1500

gaggccaucu ccaucgagau cgccuccuga                                      1530


<210>  372
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  372
auguccgucg ucggccucga cgucggcucc caguccugcu acaucgccgu cgcccgcgcc       60

ggcggcaucg agaccaucgc caacgaguuc uccgaccgcu gcacccccuc cgucaucucc      120

uucggcucca agaaccgcac caucggcguc gccgccaaga accagcagau cacccacgcc      180

aacaacaccg ucuccaacuu caagcgcuuc cacggccgcg ccuucaacga ccccuucauc      240

cagaaggaga aggagaaccu cuccuacgac cucguccccc ucaagaacgg cggcgucggc      300

aucaagguca uguacauggg cgaggagcac cucuucuccg ucgagcagau caccgccaug      360

cuccucacca agcucaagga gaccgccgag aacucccuca agaagcccgu caccgacugc      420

gucaucuccg uccccuccuu cuucaccgac gccgagcgcc gcuccguccu cgacgccgcc      480

cagaucgucg gccucaacug ccuccgccuc augaacgaca ugaccgccgu cgcccucaac      540

uacggcaucu acaagcagga ccuccccucc cucgacgaga agccccgcau cgucgucuuc      600

gucgacaugg gccacuccgc cuuccagguc uccgccugcg ccuucaacaa gggcaagcuc      660

aagguccucg gcaccgccuu cgaccccuuc cucggcggca agaacuucga cgagaagcuc      720

gucgagcacu ucugcgccga guucaagacc aaguacaagc ucgacgccaa guccaagauc      780

cgcgcccucc uccgccucua ccaggagugc gagaagcuca agaagcucau guccuccaac      840

uccaccgacc ucccccucaa caucgagugc uucaugaacg acaaggacgu cuccggcaag      900

augaaccgcu cccaguucga ggagcucugc gccgagcucc uccagaagau cgaggucccc      960

cucuacuccc uccucgagca gacccaccuc aaggucgagg acgucuccgc cgucgagauc     1020

gucggcggcg ccacccgcau ccccgccguc aaggagcgca ucgccaaguu cuucggcaag     1080

gacaucucca ccacccucaa cgccgacgag gccgucgccc gcggcugcgc ccuccagugc     1140

gccauccucu cccccgccuu caagguccgc gaguucuccg ucaccgacgc cguccccuuc     1200

cccaucuccc ucaucuggaa ccacgacucc gaggacaccg agggcgucca cgaggucuuc     1260

ucccgcaacc acgccgcccc cuucuccaag guccucaccu uccuccgccg cggccccuuc     1320

gagcucgagg ccuucuacuc cgacccccag ggcguccccu accccgaggc caagaucggc     1380

cgcuucgucg uccagaacgu cuccgcccag aaggacggcg agaagucccg cgucaagguc     1440

aagguccgcg ucaacaccca cggcaucuuc accaucucca ccgccuccau ggucgagaag     1500

guccccaccg aggagaacga gauguccucc gaggccgaca uggagugccu caaccagcgc     1560

ccccccgaga accccgacac cgacaagaac guccagcagg acaacuccga ggccggcacc     1620

cagccccagg uccagaccga cgcccagcag accucccagu ccccccccuc ccccgagcuc     1680

accuccgagg agaacaagau ccccgacgcc gacaaggcca acgagaagaa ggucgaccag     1740

ccccccgagg ccaagaagcc caagaucaag gucgucaacg ucgagcuccc caucgaggcc     1800

aaccucgucu ggcagcucgg caaggaccuc cucaacaugu acaucgagac cgagggcaag     1860

augaucaugc aggacaagcu cgagaaggag cgcaacgacg ccaagaacgc cgucgaggag     1920

uacgucuacg aguuccgcga caagcucugc ggccccuacg agaaguucau cugcgagcag     1980

gaccaccaga acuuccuccg ccuccucacc gagaccgagg acuggcucua cgaggagggc     2040

gaggaccagg ccaagcaggc cuacgucgac aagcucgagg agcucaugaa gaucggcacc     2100

cccgucaagg uccgcuucca ggaggccgag gagcgcccca agauguucga ggagcucggc     2160

cagcgccucc agcacuacgc caagaucgcc gccgacuucc gcaacaagga cgagaaguac     2220

aaccacaucg acgaguccga gaugaagaag gucgagaagu ccgucaacga ggucauggag     2280

uggaugaaca acgucaugaa cgcccaggcc aagaaguccc ucgaccagga ccccgucguc     2340

cgcgcccagg agaucaagac caagaucaag gagcucaaca acaccugcga gcccgucguc     2400

acccagccca agcccaagau cgaguccccc aagcucgagc gcacccccaa cggccccaac     2460

aucgacaaga aggaggagga ccucgaggac aagaacaacu ucggcgccga gcccccccac     2520

cagaacggcg agugcuaccc caacgagaag aacuccguca acauggaccu cgacuga        2577


<210>  373
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  373
auggccgaca agguccgccg ccagcgcccc cgccgccgcg ucugcugggc ccucgucgcc       60

guccuccucg ccgaccuccu cgcccucucc gacacccucg ccgucauguc cgucgaccuc      120

ggcuccgagu ccaugaaggu cgccaucguc aagcccggcg uccccaugga gaucguccuc      180

aacaaggagu cccgccgcaa gacccccguc aucgucaccc ucaaggagaa cgagcgcuuc      240

uucggcgacu ccgccgccuc cauggccauc aagaacccca aggccacccu ccgcuacuuc      300

cagcaccucc ucggcaagca ggccgacaac ccccacgucg cccucuacca ggcccgcuuc      360

cccgagcacg agcucaccuu cgacccccag cgccagaccg uccacuucca gaucuccucc      420

cagcuccagu ucucccccga ggagguccuc ggcauggucc ucaacuacuc ccgcucccuc      480

gccgaggacu ucgccgagca gcccaucaag gacgccguca ucaccguccc cgucuucuuc      540

aaccaggccg agcgccgcgc cguccuccag gccgcccgca uggccggccu caagguccuc      600

cagcucauca acgacaacac cgccaccgcc cucuccuacg gcgucuuccg ccgcaaggac      660

aucaacacca ccgcccagaa caucauguuc uacgacaugg gcuccggcuc caccgucugc      720

accaucguca ccuaccagau ggucaagacc aaggaggccg gcaugcagcc ccagcuccag      780

auccgcggcg ucggcuucga ccgcacccuc ggcggccucg agauggagcu ccgccuccgc      840

gagcgccucg ccggccucuu caacgagcag cgcaagggcc agcgcgccaa ggacguccgc      900

gagaaccccc gcgccauggc caagcuccuc cgcgaggcca accgccucaa gaccguccuc      960

uccgccaacg ccgaccacau ggcccagauc gagggccuca uggacgacgu cgacuucaag     1020

gccaagguca cccgcgucga guucgaggag cucugcgccg accucuucga gcgcgucccc     1080

ggccccgucc agcaggcccu ccaguccgcc gagauguccc ucgacgagau cgagcagguc     1140

auccucgucg gcggcgccac ccgcgucccc cgcguccagg agguccuccu caaggccguc     1200

ggcaaggagg agcucggcaa gaacaucaac gccgacgagg ccgccgccau gggcgccguc     1260

uaccaggccg ccgcccucuc caaggccuuc aaggucaagc ccuucgucgu ccgcgacgcc     1320

gucgucuacc ccauccucgu cgaguucacc cgcgaggucg aggaggagcc cggcauccac     1380

ucccucaagc acaacaagcg cguccucuuc ucccgcaugg gccccuaccc ccagcgcaag     1440

gucaucaccu ucaaccgcua cucccacgac uucaacuucc acaucaacua cggcgaccuc     1500

ggcuuccucg gccccgagga ccuccgcguc uucggcuccc agaaccucac caccgucaag     1560

cucaagggcg ucggcgacuc cuucaagaag uaccccgacu acgaguccaa gggcaucaag     1620

gcccacuuca accucgacga guccggcguc cucucccucg accgcgucga guccgucuuc     1680

gagacccucg ucgaggacuc cgccgaggag gaguccaccc ucaccaagcu cggcaacacc     1740

aucuccuccc ucuucggcgg cggcaccacc cccgacgcca aggagaacgg caccgacacc     1800

guccaggagg aggaggaguc ccccgccgag ggcuccaagg acgagcccgg cgagcagguc     1860

gagcucaagg aggaggccga ggcccccguc gaggacggcu cccagccccc cccccccgag     1920

cccaagggcg acgccacccc cgagggcgag aaggccaccg agaaggagaa cggcgacaag     1980

uccgaggccc agaagcccuc cgagaaggcc gaggccggcc ccgagggcgu cgcccccgcc     2040

cccgagggcg agaagaagca gaagcccgcc cgcaagcgcc gcauggucga ggagaucggc     2100

gucgagcucg ucguccucga ccuccccgac cuccccgagg acaagcucgc ccaguccguc     2160

cagaagcucc aggaccucac ccuccgcgac cucgagaagc aggagcgcga gaaggccgcc     2220

aacucccucg aggccuucau cuucgagacc caggacaagc ucuaccagcc cgaguaccag     2280

gaggucucca ccgaggagca gcgcgaggag aucuccggca agcucuccgc cgccuccacc     2340

uggcucgagg acgagggcgu cggcgccacc accgucaugc ucaaggagaa gcucgccgag     2400

cuccgcaagc ucugccaggg ccucuucuuc cgcgucgagg agcgcaagaa guggcccgag     2460

cgccucuccg cccucgacaa ccuccucaac cacuccucca uguuccucaa gggcgcccgc     2520

cucauccccg agauggacca gaucuucacc gaggucgaga ugaccacccu cgagaagguc     2580

aucaacgaga ccugggccug gaagaacgcc acccucgccg agcaggccaa gcuccccgcc     2640

accgagaagc ccguccuccu cuccaaggac aucgaggcca agaugauggc ccucgaccgc     2700

gagguccagu accuccucaa caaggccaag uucaccaagc cccgcccccg ccccaaggac     2760

aagaacggca cccgcgccga gcccccccuc aacgccuccg ccuccgacca gggcgagaag     2820

gucauccccc ccgccggcca gaccgaggac gccgagccca ucuccgagcc cgagaagguc     2880

gagaccggcu ccgagcccgg cgacaccgag ccccucgagc ucggcggccc cggcgccgag     2940

cccgagcaga aggagcaguc caccggccag aagcgccccc ucaagaacga cgagcucuga     3000


<210>  374
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  374
augcccgagg agacccagac ccaggaccag cccauggagg aggaggaggu cgagaccuuc       60

gccuuccagg ccgagaucgc ccagcucaug ucccucauca ucaacaccuu cuacuccaac      120

aaggagaucu uccuccgcga gcucaucucc aacuccuccg acgcccucga caagauccgc      180

uacgaguccc ucaccgaccc cuccaagcuc gacuccggca aggagcucca caucaaccuc      240

auccccaaca agcaggaccg cacccucacc aucgucgaca ccggcaucgg caugaccaag      300

gccgaccuca ucaacaaccu cggcaccauc gccaaguccg gcaccaaggc cuucauggag      360

gcccuccagg ccggcgccga caucuccaug aucggccagu ucggcgucgg cuucuacucc      420

gccuaccucg ucgccgagaa ggucaccguc aucaccaagc acaacgacga cgagcaguac      480

gccugggagu ccuccgccgg cggcuccuuc accguccgca ccgacaccgg cgagcccaug      540

ggccgcggca ccaaggucau ccuccaccuc aaggaggacc agaccgagua ccucgaggag      600

cgccgcauca aggagaucgu caagaagcac ucccaguuca ucggcuaccc caucacccuc      660

uucgucgaga aggagcgcga caaggagguc uccgacgacg aggccgagga gaaggaggac      720

aaggaggagg agaaggagaa ggaggagaag gaguccgagg acaagcccga gaucgaggac      780

gucggcuccg acgaggagga ggagaagaag gacggcgaca agaagaagaa gaagaagauc      840

aaggagaagu acaucgacca ggaggagcuc aacaagacca agcccaucug gacccgcaac      900

cccgacgaca ucaccaacga ggaguacggc gaguucuaca agucccucac caacgacugg      960

gaggaccacc ucgccgucaa gcacuucucc gucgagggcc agcucgaguu ccgcgcccuc     1020

cucuucgucc cccgccgcgc ccccuucgac cucuucgaga accgcaagaa gaagaacaac     1080

aucaagcucu acguccgccg cgucuucauc auggacaacu gcgaggagcu cauccccgag     1140

uaccucaacu ucauccgcgg cgucgucgac uccgaggacc ucccccucaa caucucccgc     1200

gagaugcucc agcaguccaa gauccucaag gucauccgca agaaccucgu caagaagugc     1260

cucgagcucu ucaccgagcu cgccgaggac aaggagaacu acaagaaguu cuacgagcag     1320

uucuccaaga acaucaagcu cggcauccac gaggacuccc agaaccgcaa gaagcucucc     1380

gagcuccucc gcuacuacac cuccgccucc ggcgacgaga uggucucccu caaggacuac     1440

ugcacccgca ugaaggagaa ccagaagcac aucuacuaca ucaccggcga gaccaaggac     1500

caggucgcca acuccgccuu cgucgagcgc cuccgcaagc acggccucga ggucaucuac     1560

augaucgagc ccaucgacga guacugcguc cagcagcuca aggaguucga gggcaagacc     1620

cucgucuccg ucaccaagga gggccucgag cuccccgagg acgaggagga gaagaagaag     1680

caggaggaga agaagaccaa guucgagaac cucugcaaga ucaugaagga cauccucgag     1740

aagaaggucg agaaggucgu cgucuccaac cgccucguca ccucccccug cugcaucguc     1800

accuccaccu acggcuggac cgccaacaug gagcgcauca ugaaggccca ggcccuccgc     1860

gacaacucca ccaugggcua cauggccgcc aagaagcacc ucgagaucaa ccccgaccac     1920

uccaucaucg agacccuccg ccagaaggcc gaggccgaca agaacgacaa guccgucaag     1980

gaccucguca uccuccucua cgagaccgcc cuccucuccu ccggcuucuc ccucgaggac     2040

ccccagaccc acgccaaccg caucuaccgc augaucaagc ucggccucgg caucgacgag     2100

gacgacccca ccgccgacga caccuccgcc gccgucaccg aggagaugcc cccccucgag     2160

ggcgacgacg acaccucccg cauggaggag gucgacuga                            2199


<210>  375
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  375
auggacuccu ccaagcucga cuccggcaag ggccuccaca ucaaccucgu ccccaacaag       60

cagaaccaga cccucaccau cgucgacacc cgcaucggca ugaccaagac cgaccucauc      120

aacaaccucg gcaccgucac caaguccggc accaaggccu ucauggaggc ccuccaggcc      180

gacgccgaca ucuccaugau cggccacuuc ggcgucggcu ucuacuccgc cuaccucguc      240

gccaagaagg ucaccgucau cuccaagcac aacaacgacg agcaguacac cugggagucc      300

uccgccggcg gcuccuucac cguccgcacc gacgaguga                             339


<210>  376
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  376
augcccgagg agguccacca cggcgaggag gaggucgaga ccuucgccuu ccaggccgag       60

aucgcccagc ucaugucccu caucaucaac accuucuacu ccaacaagga gaucuuccuc      120

cgcgagcuca ucuccaacgc cuccgacgcc cucgacaaga uccgcuacga gucccucacc      180

gaccccucca agcucgacuc cggcaaggag cucaagaucg acaucauccc caacccccag      240

gagcgcaccc ucacccucgu cgacaccggc aucggcauga ccaaggccga ccucaucaac      300

aaccucggca ccaucgccaa guccggcacc aaggccuuca uggaggcccu ccaggccggc      360

gccgacaucu ccaugaucgg ccaguucggc gucggcuucu acuccgccua ccucgucgcc      420

gagaaggucg ucgucaucac caagcacaac gacgacgagc aguacgccug ggaguccucc      480

gccggcggcu ccuucaccgu ccgcgccgac cacggcgagc ccaucggccg cggcaccaag      540

gucauccucc accucaagga ggaccagacc gaguaccucg aggagcgccg cgucaaggag      600

gucgucaaga agcacuccca guucaucggc uaccccauca cccucuaccu cgagaaggag      660

cgcgagaagg agaucuccga cgacgaggcc gaggaggaga agggcgagaa ggaggaggag      720

gacaaggacg acgaggagaa gcccaagauc gaggacgucg gcuccgacga ggaggacgac      780

uccggcaagg acaagaagaa gaagaccaag aagaucaagg agaaguacau cgaccaggag      840

gagcucaaca agaccaagcc caucuggacc cgcaaccccg acgacaucac ccaggaggag      900

uacggcgagu ucuacaaguc ccucaccaac gacugggagg accaccucgc cgucaagcac      960

uucuccgucg agggccagcu cgaguuccgc gcccuccucu ucaucccccg ccgcgccccc     1020

uucgaccucu ucgagaacaa gaagaagaag aacaacauca agcucuacgu ccgccgcguc     1080

uucaucaugg acuccugcga cgagcucauc cccgaguacc ucaacuucau ccgcggcguc     1140

gucgacuccg aggaccuccc ccucaacauc ucccgcgaga ugcuccagca guccaagauc     1200

cucaagguca uccgcaagaa caucgucaag aagugccucg agcucuucuc cgagcucgcc     1260

gaggacaagg agaacuacaa gaaguucuac gaggccuucu ccaagaaccu caagcucggc     1320

auccacgagg acuccaccaa ccgccgccgc cucuccgagc uccuccgcua ccacaccucc     1380

caguccggcg acgagaugac cucccucucc gaguacgucu cccgcaugaa ggagacccag     1440

aaguccaucu acuacaucac cggcgagucc aaggagcagg ucgccaacuc cgccuucguc     1500

gagcgcgucc gcaagcgcgg cuucgagguc gucuacauga ccgagcccau cgacgaguac     1560

ugcguccagc agcucaagga guucgacggc aagucccucg ucuccgucac caaggagggc     1620

cucgagcucc ccgaggacga ggaggagaag aagaagaugg aggaguccaa ggccaaguuc     1680

gagaaccucu gcaagcucau gaaggagauc cucgacaaga aggucgagaa ggucaccauc     1740

uccaaccgcc ucgucuccuc ccccugcugc aucgucaccu ccaccuacgg cuggaccgcc     1800

aacauggagc gcaucaugaa ggcccaggcc cuccgcgaca acuccaccau gggcuacaug     1860

auggccaaga agcaccucga gaucaacccc gaccacccca ucgucgagac ccuccgccag     1920

aaggccgagg ccgacaagaa cgacaaggcc gucaaggacc ucgucguccu ccucuucgag     1980

accgcccucc ucuccuccgg cuucucccuc gaggaccccc agacccacuc caaccgcauc     2040

uaccgcauga ucaagcucgg ccucggcauc gacgaggacg aggucgccgc cgaggagccc     2100

aacgccgccg uccccgacga gauccccccc cucgagggcg acgaggacgc cucccgcaug     2160

gaggaggucg acuga                                                      2175


<210>  377
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  377
augcgcgccc ucuggguccu cggccucugc ugcguccucc ucaccuucgg cuccguccgc       60

gccgacgacg aggucgacgu cgacggcacc gucgaggagg accucggcaa gucccgcgag      120

ggcucccgca ccgacgacga ggucguccag cgcgaggagg aggccaucca gcucgacggc      180

cucaacgccu cccagauccg cgagcuccgc gagaaguccg agaaguucgc cuuccaggcc      240

gaggucaacc gcaugaugaa gcucaucauc aacucccucu acaagaacaa ggagaucuuc      300

cuccgcgagc ucaucuccaa cgccuccgac gcccucgaca agauccgccu caucucccuc      360

accgacgaga acgcccucuc cggcaacgag gagcucaccg ucaagaucaa gugcgacaag      420

gagaagaacc uccuccacgu caccgacacc ggcgucggca ugacccgcga ggagcucguc      480

aagaaccucg gcaccaucgc caaguccggc accuccgagu uccucaacaa gaugaccgag      540

gcccaggagg acggccaguc caccuccgag cucaucggcc aguucggcgu cggcuucuac      600

uccgccuucc ucgucgccga caaggucauc gucaccucca agcacaacaa cgacacccag      660

cacaucuggg aguccgacuc caacgaguuc uccgucaucg ccgacccccg cggcaacacc      720

cucggccgcg gcaccaccau cacccucguc cucaaggagg aggccuccga cuaccucgag      780

cucgacacca ucaagaaccu cgucaagaag uacucccagu ucaucaacuu ccccaucuac      840

gucugguccu ccaagaccga gaccgucgag gagcccaugg aggaggagga ggccgccaag      900

gaggagaagg aggaguccga cgacgaggcc gccgucgagg aggaggagga ggagaagaag      960

cccaagacca agaaggucga gaagaccguc ugggacuggg agcucaugaa cgacaucaag     1020

cccaucuggc agcgccccuc caaggagguc gaggaggacg aguacaaggc cuucuacaag     1080

uccuucucca aggaguccga cgaccccaug gccuacaucc acuucaccgc cgagggcgag     1140

gucaccuuca aguccauccu cuucgucccc accuccgccc cccgcggccu cuucgacgag     1200

uacggcucca agaaguccga cuacaucaag cucuacgucc gccgcgucuu caucaccgac     1260

gacuuccacg acaugaugcc caaguaccuc aacuucguca agggcgucgu cgacuccgac     1320

gaccuccccc ucaacgucuc ccgcgagacc cuccagcagc acaagcuccu caaggucauc     1380

cgcaagaagc ucguccgcaa gacccucgac augaucaaga agaucgccga cgacaaguac     1440

aacgacaccu ucuggaagga guucggcacc aacaucaagc ucggcgucau cgaggaccac     1500

uccaaccgca cccgccucgc caagcuccuc cgcuuccagu ccucccacca ccccaccgac     1560

aucaccuccc ucgaccagua cgucgagcgc augaaggaga agcaggacaa gaucuacuuc     1620

auggccggcu ccucccgcaa ggaggccgag uccucccccu ucgucgagcg ccuccucaag     1680

aagggcuacg aggucaucua ccucaccgag cccgucgacg aguacugcau ccaggcccuc     1740

cccgaguucg acggcaagcg cuuccagaac gucgccaagg agggcgucaa guucgacgag     1800

uccgagaaga ccaaggaguc ccgcgaggcc gucgagaagg aguucgagcc ccuccucaac     1860

uggaugaagg acaaggcccu caaggacaag aucgagaagg ccgucgucuc ccagcgccuc     1920

accgaguccc ccugcgcccu cgucgccucc caguacggcu gguccggcaa cauggagcgc     1980

aucaugaagg cccaggccua ccagaccggc aaggacaucu ccaccaacua cuacgccucc     2040

cagaagaaga ccuucgagau caacccccgc cacccccuca uccgcgacau gcuccgccgc     2100

aucaaggagg acgaggacga caagaccguc cucgaccucg ccgucguccu cuucgagacc     2160

gccacccucc gcuccggcua ccuccucccc gacaccaagg ccuacggcga ccgcaucgag     2220

cgcaugcucc gccucucccu caacaucgac cccgacgcca aggucgagga ggagcccgag     2280

gaggagcccg aggagaccgc cgaggacacc accgaggaca ccgagcagga cgaggacgag     2340

gagauggacg ucggcaccga cgaggaggag gagaccgcca aggaguccac cgccgagaag     2400

gacgagcucu ga                                                         2412


<210>  378
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  378
auggcccgcg agcuccgcgc ccuccuccuc uggggccgcc gccuccgccc ccuccuccgc       60

gcccccgccc ucgccgccgu ccccggcggc aagcccaucc ucugcccccg ccgcaccacc      120

gcccagcucg gcccccgccg caaccccgcc uggucccucc aggccggccg ccucuucucc      180

acccagaccg ccgaggacaa ggaggagccc cuccacucca ucaucuccuc caccgagucc      240

guccagggcu ccaccuccaa gcacgaguuc caggccgaga ccaagaagcu ccucgacauc      300

gucgcccgcu cccucuacuc cgagaaggag gucuucaucc gcgagcucau cuccaacgcc      360

uccgacgccc ucgagaagcu ccgccacaag cucgucuccg acggccaggc ccuccccgag      420

auggagaucc accuccagac caacgccgag aagggcacca ucaccaucca ggacaccggc      480

aucggcauga cccaggagga gcucgucucc aaccucggca ccaucgcccg cuccggcucc      540

aaggccuucc ucgacgcccu ccagaaccag gccgaggccu ccuccaagau caucggccag      600

uucggcgucg gcuucuacuc cgccuucaug gucgccgacc gcgucgaggu cuacucccgc      660

uccgccgccc ccggcucccu cggcuaccag uggcucuccg acggcuccgg cgucuucgag      720

aucgccgagg ccuccggcgu ccgcaccggc accaagauca ucauccaccu caaguccgac      780

ugcaaggagu ucuccuccga ggcccgcguc cgcgacgucg ucaccaagua cuccaacuuc      840

gucuccuucc cccucuaccu caacggccgc cgcaugaaca cccuccaggc caucuggaug      900

auggacccca aggacguccg cgaguggcag cacgaggagu ucuaccgcua cgucgcccag      960

gcccacgaca agccccgcua cacccuccac uacaagaccg acgccccccu caacauccgc     1020

uccaucuucu acguccccga caugaagccc uccauguucg acgucucccg cgagcucggc     1080

uccuccgucg cccucuacuc ccgcaagguc cucauccaga ccaaggccac cgacauccuc     1140

cccaaguggc uccgcuucau ccgcggcguc gucgacuccg aggacauccc ccucaaccuc     1200

ucccgcgagc uccuccagga guccgcccuc auccgcaagc uccgcgacgu ccuccagcag     1260

cgccucauca aguucuucau cgaccagucc aagaaggacg ccgagaagua cgccaaguuc     1320

uucgaggacu acggccucuu caugcgcgag ggcaucguca ccgccaccga gcaggagguc     1380

aaggaggaca ucgccaagcu ccuccgcuac gaguccuccg cccuccccuc cggccagcuc     1440

accucccucu ccgaguacgc cucccgcaug cgcgccggca cccgcaacau cuacuaccuc     1500

ugcgccccca accgccaccu cgccgagcac ucccccuacu acgaggccau gaagaagaag     1560

gacaccgagg uccucuucug cuucgagcag uucgacgagc ucacccuccu ccaccuccgc     1620

gaguucgaca agaagaagcu caucuccguc gagaccgaca ucgucgucga ccacuacaag     1680

gaggagaagu ucgaggaccg cucccccgcc gccgagugcc ucuccgagaa ggagaccgag     1740

gagcucaugg ccuggaugcg caacguccuc ggcucccgcg ucaccaacgu caaggucacc     1800

cuccgccucg acacccaccc cgccaugguc accguccucg agaugggcgc cgcccgccac     1860

uuccuccgca ugcagcagcu cgccaagacc caggaggagc gcgcccagcu ccuccagccc     1920

acccucgaga ucaacccccg ccacgcccuc aucaagaagc ucaaccagcu ccgcgccucc     1980

gagcccggcc ucgcccagcu ccucgucgac cagaucuacg agaacgccau gaucgccgcc     2040

ggccucgucg acgacccccg cgccaugguc ggccgccuca acgagcuccu cgucaaggcc     2100

cucgagcgcc acuga                                                      2115


<210>  379
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  379
augggcaaga ucuccucccu ccccacccag cucuucaagu gcugcuucug cgacuuccuc       60

aaggucaaga ugcacaccau guccuccucc caccucuucu accucgcccu cugccuccuc      120

accuucaccu ccuccgccac cgccggcccc gagacccucu gcggcgccga gcucgucgac      180

gcccuccagu ucgucugcgg cgaccgcggc uucuacuuca acaagcccac cggcuacggc      240

uccuccuccc gccgcgcccc ccagaccggc aucgucgacg agugcugcuu ccgcuccugc      300

gaccuccgcc gccucgagau guacugcgcc ccccucaagc ccgccaaguc cgcccgcucc      360

guccgcgccc agcgccacac cgacaugccc aagacccaga aggaggucca ccucaagaac      420

gccucccgcg gcuccgccgg caacaagaac uaccgcaugu ga                         462


<210>  380
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  380
augggcaucc ccaugggcaa guccaugcuc guccuccuca ccuuccucgc cuucgccucc       60

ugcugcaucg ccgccuaccg ccccuccgag acccucugcg gcggcgagcu cgucgacacc      120

cuccaguucg ucugcggcga ccgcggcuuc uacuucuccc gccccgccuc ccgcgucucc      180

cgccgcuccc gcggcaucgu cgaggagugc ugcuuccgcu ccugcgaccu cgcccuccuc      240

gagaccuacu gcgccacccc cgccaagucc gagcgcgacg ucuccacccc ccccaccguc      300

cuccccgaca acuucccccg cuaccccguc ggcaaguucu uccaguacga caccuggaag      360

caguccaccc agcgccuccg ccgcggccuc cccgcccucc uccgcgcccg ccgcggccac      420

guccucgcca aggagcucga ggccuuccgc gaggccaagc gccaccgccc ccucaucgcc      480

cuccccaccc aggaccccgc ccacggcggc gccccccccg agauggccuc caaccgcaag      540

uga                                                                    543


<210>  381
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  381
augaacuccu ucuccaccuc cgccuucggc cccgucgccu ucucccucgg ccuccuccuc       60

guccuccccg ccgccuuccc cgcccccguc ccccccggcg aggacuccaa ggacgucgcc      120

gccccccacc gccagccccu caccuccucc gagcgcaucg acaagcagau ccgcuacauc      180

cucgacggca ucuccgcccu ccgcaaggag accugcaaca aguccaacau gugcgagucc      240

uccaaggagg cccucgccga gaacaaccuc aaccucccca agauggccga gaaggacggc      300

ugcuuccagu ccggcuucaa cgaggagacc ugccucguca agaucaucac cggccuccuc      360

gaguucgagg ucuaccucga guaccuccag aaccgcuucg aguccuccga ggagcaggcc      420

cgcgccgucc agauguccac caagguccuc auccaguucc uccagaagaa ggccaagaac      480

cucgacgcca ucaccacccc cgaccccacc accaacgccu cccuccucac caagcuccag      540

gcccagaacc aguggcucca ggacaugacc acccaccuca uccuccgcuc cuucaaggag      600

uuccuccagu ccucccuccg cgcccuccgc cagauguga                             639


<210>  382
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  382
augccccucc ucuggcuccg cggcuuccuc cucgccuccu gcuggaucau cguccgcucc       60

ucccccaccc ccggcuccga gggccacucc gccgcccccg acugccccuc cugcgcccuc      120

gccgcccucc ccaaggacgu ccccaacucc cagcccgaga uggucgaggc cgucaagaag      180

cacauccuca acaugcucca ccucaagaag cgccccgacg ucacccagcc cguccccaag      240

gccgcccucc ucaacgccau ccgcaagcuc cacgucggca aggucggcga gaacggcuac      300

gucgagaucg aggacgacau cggccgccgc gccgagauga acgagcucau ggagcagacc      360

uccgagauca ucaccuucgc cgaguccggc accgcccgca agacccucca cuucgagauc      420

uccaaggagg gcuccgaccu cuccgucguc gagcgcgccg aggucuggcu cuuccucaag      480

guccccaagg ccaaccgcac ccgcaccaag gucaccaucc gccucuucca gcagcagaag      540

cacccccagg gcucccucga caccggcgag gaggccgagg aggucggccu caagggcgag      600

cgcuccgagc uccuccucuc cgagaagguc gucgacgccc gcaaguccac cuggcacguc      660

uuccccgucu ccuccuccau ccagcgccuc cucgaccagg gcaaguccuc ccucgacguc      720

cgcaucgccu gcgagcagug ccaggagucc ggcgccuccc ucguccuccu cggcaagaag      780

aagaagaagg aggaggaggg cgagggcaag aagaagggcg gcggcgaggg cggcgccggc      840

gccgacgagg agaaggagca gucccaccgc cccuuccuca ugcuccaggc ccgccagucc      900

gaggaccacc cccaccgccg ccgccgccgc ggccucgagu gcgacggcaa ggucaacauc      960

ugcugcaaga agcaguucuu cgucuccuuc aaggacaucg gcuggaacga cuggaucauc     1020

gcccccuccg gcuaccacgc caacuacugc gagggcgagu gccccuccca caucgccggc     1080

accuccggcu ccucccucuc cuuccacucc accgucauca accacuaccg caugcgcggc     1140

cacucccccu ucgccaaccu caaguccugc ugcgucccca ccaagcuccg ccccaugucc     1200

augcucuacu acgacgacgg ccagaacauc aucaagaagg acauccagaa caugaucguc     1260

gaggagugcg gcugcuccug a                                               1281


<210>  383
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  383
auggacggcc uccccggccg cgcccucggc gccgccugcc uccuccuccu cgccgccggc       60

uggcucggcc ccgaggccug gggcuccccc accccccccc ccacccccgc cgcccccccc      120

cccccccccc cccccggcuc ccccggcggc ucccaggaca ccugcaccuc cugcggcggc      180

uuccgccgcc ccgaggagcu cggccgcguc gacggcgacu uccucgaggc cgucaagcgc      240

cacauccucu cccgccucca gaugcgcggc cgccccaaca ucacccacgc cguccccaag      300

gccgccaugg ucaccgcccu ccgcaagcuc cacgccggca agguccgcga ggacggccgc      360

gucgagaucc cccaccucga cggccacgcc ucccccggcg ccgacggcca ggagcgcguc      420

uccgagauca ucuccuucgc cgagaccgac ggccucgccu ccucccgcgu ccgccucuac      480

uucuucaucu ccaacgaggg caaccagaac cucuucgucg uccaggccuc ccucuggcuc      540

uaccucaagc uccuccccua cguccucgag aagggcuccc gccgcaaggu ccgcgucaag      600

gucuacuucc aggagcaggg ccacggcgac cgcuggaaca uggucgagaa gcgcgucgac      660

cucaagcgcu ccggcuggca caccuucccc cucaccgagg ccauccaggc ccucuucgag      720

cgcggcgagc gccgccucaa ccucgacguc cagugcgacu ccugccagga gcucgccguc      780

guccccgucu ucgucgaccc cggcgaggag ucccaccgcc ccuucgucgu cguccaggcc      840

cgccucggcg acucccgcca ccgcauccgc aagcgcggcc ucgagugcga cggccgcacc      900

aaccucugcu gccgccagca guucuucauc gacuuccgcc ucaucggcug gaacgacugg      960

aucaucgccc ccaccggcua cuacggcaac uacugcgagg gcuccugccc cgccuaccuc     1020

gccggcgucc ccggcuccgc cuccuccuuc cacaccgccg ucgucaacca guaccgcaug     1080

cgcggccuca accccggcac cgucaacucc ugcugcaucc ccaccaagcu cuccaccaug     1140

uccaugcucu acuucgacga cgaguacaac aucgucaagc gcgacguccc caacaugauc     1200

gucgaggagu gcggcugcgc cuga                                            1224


<210>  384
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  384
auggcccucc gcguccuccu ccucaccgcc cucacccucu gccacggcuu caaccucgac       60

accgagaacg ccaugaccuu ccaggagaac gcccgcggcu ucggccaguc cgucguccag      120

cuccagggcu cccgcgucgu cgucggcgcc ccccaggaga ucgucgccgc caaccagcgc      180

ggcucccucu accagugcga cuacuccacc ggcuccugcg agcccauccg ccuccagguc      240

cccgucgagg ccgucaacau gucccucggc cucucccucg ccgccaccac cucccccccc      300

cagcuccucg ccugcggccc caccguccac cagaccugcu ccgagaacac cuacgucaag      360

ggccucugcu uccucuucgg cuccaaccuc cgccagcagc cccagaaguu ccccgaggcc      420

cuccgcggcu gcccccagga ggacuccgac aucgccuucc ucaucgacgg cuccggcucc      480

aucauccccc acgacuuccg ccgcaugaag gaguucgucu ccaccgucau ggagcagcuc      540

aagaagucca agacccucuu cucccucaug caguacuccg aggaguuccg cauccacuuc      600

accuucaagg aguuccagaa caaccccaac ccccgcuccc ucgucaagcc caucacccag      660

cuccucggcc gcacccacac cgccaccggc auccgcaagg ucguccgcga gcucuucaac      720

aucaccaacg gcgcccgcaa gaacgccuuc aagauccucg ucgucaucac cgacggcgag      780

aaguucggcg acccccucgg cuacgaggac gucauccccg aggccgaccg cgagggcguc      840

auccgcuacg ucaucggcgu cggcgacgcc uuccgcuccg agaagucccg ccaggagcuc      900

aacaccaucg ccuccaagcc cccccgcgac cacgucuucc aggucaacaa cuucgaggcc      960

cucaagacca uccagaacca gcuccgcgag aagaucuucg ccaucgaggg cacccagacc     1020

ggcuccuccu ccuccuucga gcacgagaug ucccaggagg gcuucuccgc cgccaucacc     1080

uccaacggcc cccuccucuc caccgucggc uccuacgacu gggccggcgg cgucuuccuc     1140

uacaccucca aggagaaguc caccuucauc aacaugaccc gcgucgacuc cgacaugaac     1200

gacgccuacc ucggcuacgc cgccgccauc auccuccgca accgcgucca gucccucguc     1260

cucggcgccc cccgcuacca gcacaucggc cucgucgcca uguuccgcca gaacaccggc     1320

augugggagu ccaacgccaa cgucaagggc acccagaucg gcgccuacuu cggcgccucc     1380

cucugcuccg ucgacgucga cuccaacggc uccaccgacc ucguccucau cggcgccccc     1440

cacuacuacg agcagacccg cggcggccag gucuccgucu gcccccuccc ccgcggccgc     1500

gcccgcuggc agugcgacgc cguccucuac ggcgagcagg gccagcccug gggccgcuuc     1560

ggcgccgccc ucaccguccu cggcgacguc aacggcgaca agcucaccga cgucgccauc     1620

ggcgcccccg gcgaggagga caaccgcggc gccgucuacc ucuuccacgg caccuccggc     1680

uccggcaucu cccccuccca cucccagcgc aucgccggcu ccaagcucuc cccccgccuc     1740

caguacuucg gccagucccu cuccggcggc caggaccuca ccauggacgg ccucgucgac     1800

cucaccgucg gcgcccaggg ccacguccuc cuccuccgcu cccagcccgu ccuccgcguc     1860

aaggccauca uggaguucaa cccccgcgag gucgcccgca acgucuucga gugcaacgac     1920

caggucguca agggcaagga ggccggcgag guccgcgucu gccuccacgu ccagaagucc     1980

acccgcgacc gccuccgcga gggccagauc caguccgucg ucaccuacga ccucgcccuc     2040

gacuccggcc gcccccacuc ccgcgccguc uucaacgaga ccaagaacuc cacccgccgc     2100

cagacccagg uccucggccu cacccagacc ugcgagaccc ucaagcucca gcuccccaac     2160

ugcaucgagg accccgucuc ccccaucguc cuccgccuca acuucucccu cgucggcacc     2220

ccccucuccg ccuucggcaa ccuccgcccc guccucgccg aggacgccca gcgccucuuc     2280

accgcccucu uccccuucga gaagaacugc ggcaacgaca acaucugcca ggacgaccuc     2340

uccaucaccu ucuccuucau gucccucgac ugccucgucg ucggcggccc ccgcgaguuc     2400

aacgucaccg ucaccguccg caacgacggc gaggacuccu accgcaccca ggucaccuuc     2460

uucuuccccc ucgaccucuc cuaccgcaag gucuccaccc uccagaacca gcgcucccag     2520

cgcuccuggc gccucgccug cgaguccgcc uccuccaccg aggucuccgg cgcccucaag     2580

uccaccuccu gcuccaucaa ccaccccauc uuccccgaga acuccgaggu caccuucaac     2640

aucaccuucg acgucgacuc caaggccucc cucggcaaca agcuccuccu caaggccaac     2700

gucaccuccg agaacaacau gccccgcacc aacaagaccg aguuccagcu cgagcucccc     2760

gucaaguacg ccgucuacau ggucgucacc ucccacggcg ucuccaccaa guaccucaac     2820

uucaccgccu ccgagaacac cucccgcguc augcagcacc aguaccaggu cuccaaccuc     2880

ggccagcgcu cccuccccau cucccucguc uuccucgucc ccguccgccu caaccagacc     2940

gucaucuggg accgccccca ggucaccuuc uccgagaacc ucuccuccac cugccacacc     3000

aaggagcgcc uccccuccca cuccgacuuc cucgccgagc uccgcaaggc ccccgucguc     3060

aacugcucca ucgccgucug ccagcgcauc cagugcgaca uccccuucuu cggcauccag     3120

gaggaguuca acgccacccu caagggcaac cucuccuucg acugguacau caagaccucc     3180

cacaaccacc uccucaucgu cuccaccgcc gagauccucu ucaacgacuc cgucuucacc     3240

cuccuccccg gccagggcgc cuucguccgc ucccagaccg agaccaaggu cgagcccuuc     3300

gaggucccca acccccuccc ccucaucguc ggcuccuccg ucggcggccu ccuccuccuc     3360

gcccucauca ccgccgcccu cuacaagcuc ggcuucuuca agcgccagua caaggacaug     3420

auguccgagg gcggcccccc cggcgccgag ccccaguga                            3459


<210>  385
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  385
auguucuccc ucaagacccu ccccuuccuc cuccuccucc acguccagau cuccaaggcc       60

uuccccgucu ccuccaagga gaagaacacc aagaccgucc aggacuaccu cgagaaguuc      120

uaccagcucc ccuccaacca guaccagucc acccgcaaga acggcaccaa cgucaucguc      180

gagaagcuca aggagaugca gcgcuucuuc ggccucaacg ucaccggcaa gcccaacgag      240

gagacccucg acaugaugaa gaagccccgc ugcggcgucc ccgacuccgg cggcuucaug      300

cucacccccg gcaaccccaa gugggagcgc accaaccuca ccuaccgcau ccgcaacuac      360

accccccagc ucuccgaggc cgaggucgag cgcgccauca aggacgccuu cgagcucugg      420

uccgucgccu ccccccucau cuucacccgc aucucccagg gcgaggccga caucaacauc      480

gccuucuacc agcgcgacca cggcgacaac ucccccuucg acggccccaa cggcauccuc      540

gcccacgccu uccagcccgg ccagggcauc ggcggcgacg cccacuucga cgccgaggag      600

accuggacca acaccuccgc caacuacaac cucuuccucg ucgccgccca cgaguucggc      660

cacucccucg gccucgccca cuccuccgac cccggcgccc ucauguaccc caacuacgcc      720

uuccgcgaga ccuccaacua cucccucccc caggacgaca ucgacggcau ccaggccauc      780

uacggccucu ccuccaaccc cauccagccc accggccccu ccacccccaa gcccugcgac      840

cccucccuca ccuucgacgc caucaccacc cuccgcggcg agauccucuu cuucaaggac      900

cgcuacuucu ggcgccgcca cccccagcuc cagcgcgucg agaugaacuu caucucccuc      960

uucuggcccu cccuccccac cggcauccag gccgccuacg aggacuucga ccgcgaccuc     1020

aucuuccucu ucaagggcaa ccaguacugg gcccucuccg gcuacgacau ccuccagggc     1080

uaccccaagg acaucuccaa cuacggcuuc cccuccuccg uccaggccau cgacgccgcc     1140

gucuucuacc gcuccaagac cuacuucuuc gucaacgacc aguucuggcg cuacgacaac     1200

cagcgccagu ucauggagcc cggcuacccc aaguccaucu ccggcgccuu ccccggcauc     1260

gaguccaagg ucgacgccgu cuuccagcag gagcacuucu uccacgucuu cuccggcccc     1320

cgcuacuacg ccuucgaccu caucgcccag cgcgucaccc gcgucgcccg cggcaacaag     1380

uggcucaacu gccgcuacgg cuga                                            1404


<210>  386
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  386
augucccucu ggcagccccu cguccucguc cuccucgucc ucggcugcug cuucgccgcc       60

ccccgccagc gccaguccac ccucguccuc uuccccggcg accuccgcac caaccucacc      120

gaccgccagc ucgccgagga guaccucuac cgcuacggcu acacccgcgu cgccgagaug      180

cgcggcgagu ccaagucccu cggccccgcc cuccuccucc uccagaagca gcucucccuc      240

cccgagaccg gcgagcucga cuccgccacc cucaaggcca ugcgcacccc ccgcugcggc      300

guccccgacc ucggccgcuu ccagaccuuc gagggcgacc ucaaguggca ccaccacaac      360

aucaccuacu ggauccagaa cuacuccgag gaccuccccc gcgccgucau cgacgacgcc      420

uucgcccgcg ccuucgcccu cugguccgcc gucacccccc ucaccuucac ccgcgucuac      480

ucccgcgacg ccgacaucgu cauccaguuc ggcgucgccg agcacggcga cggcuacccc      540

uucgacggca aggacggccu ccucgcccac gccuuccccc ccggccccgg cauccagggc      600

gacgcccacu ucgacgacga cgagcucugg ucccucggca agggcgucgu cguccccacc      660

cgcuucggca acgccgacgg cgccgccugc cacuuccccu ucaucuucga gggccgcucc      720

uacuccgccu gcaccaccga cggccgcucc gacggccucc ccuggugcuc caccaccgcc      780

aacuacgaca ccgacgaccg cuucggcuuc ugccccuccg agcgccucua cacccaggac      840

ggcaacgccg acggcaagcc cugccaguuc cccuucaucu uccagggcca guccuacucc      900

gccugcacca ccgacggccg cuccgacggc uaccgcuggu gcgccaccac cgccaacuac      960

gaccgcgaca agcucuucgg cuucugcccc acccgcgccg acuccaccgu caugggcggc     1020

aacuccgccg gcgagcucug cgucuucccc uucaccuucc ucggcaagga guacuccacc     1080

ugcaccuccg agggccgcgg cgacggccgc cucuggugcg ccaccaccuc caacuucgac     1140

uccgacaaga aguggggcuu cugccccgac cagggcuacu cccucuuccu cgucgccgcc     1200

cacgaguucg gccacgcccu cggccucgac cacuccuccg uccccgaggc ccucauguac     1260

cccauguacc gcuucaccga gggccccccc cuccacaagg acgacgucaa cggcauccgc     1320

caccucuacg gcccccgccc cgagcccgag ccccgccccc ccaccaccac caccccccag     1380

cccaccgccc cccccaccgu cugccccacc ggccccccca ccguccaccc cuccgagcgc     1440

cccaccgccg gccccaccgg cccccccucc gccggcccca ccggcccccc caccgccggc     1500

cccuccaccg ccaccaccgu cccccucucc cccgucgacg acgccugcaa cgucaacauc     1560

uucgacgcca ucgccgagau cggcaaccag cucuaccucu ucaaggacgg caaguacugg     1620

cgcuucuccg agggccgcgg cucccgcccc cagggccccu uccucaucgc cgacaagugg     1680

cccgcccucc cccgcaagcu cgacuccguc uucgaggagc gccucuccaa gaagcucuuc     1740

uucuucuccg gccgccaggu cugggucuac accggcgccu ccguccucgg cccccgccgc     1800

cucgacaagc ucggccucgg cgccgacguc gcccagguca ccggcgcccu ccgcuccggc     1860

cgcggcaaga ugcuccucuu cuccggccgc cgccucuggc gcuucgacgu caaggcccag     1920

auggucgacc cccgcuccgc cuccgagguc gaccgcaugu uccccggcgu cccccucgac     1980

acccacgacg ucuuccagua ccgcgagaag gccuacuucu gccaggaccg cuucuacugg     2040

cgcgucuccu cccgcuccga gcucaaccag gucgaccagg ucggcuacgu caccuacgac     2100

auccuccagu gccccgagga cuga                                            2124


<210>  387
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  387
augcaccccg gcguccucgc cgccuuccuc uuccucuccu ggacccacug ccgcgcccuc       60

ccccuccccu ccggcggcga cgaggacgac cucuccgagg aggaccucca guucgccgag      120

cgcuaccucc gcuccuacua ccaccccacc aaccucgccg gcauccucaa ggagaacgcc      180

gccuccucca ugaccgagcg ccuccgcgag augcaguccu ucuucggccu cgaggucacc      240

ggcaagcucg acgacaacac ccucgacguc augaagaagc cccgcugcgg cguccccgac      300

gucggcgagu acaacgucuu cccccgcacc cucaaguggu ccaagaugaa ccucaccuac      360

cgcaucguca acuacacccc cgacaugacc cacuccgagg ucgagaaggc cuucaagaag      420

gccuucaagg ucugguccga cgucaccccc cucaacuuca cccgccucca cgacggcauc      480

gccgacauca ugaucuccuu cggcaucaag gagcacggcg acuucuaccc cuucgacggc      540

cccuccggcc uccucgccca cgccuucccc cccggcccca acuacggcgg cgacgcccac      600

uucgacgacg acgagaccug gaccuccucc uccaagggcu acaaccucuu ccucgucgcc      660

gcccacgagu ucggccacuc ccucggccuc gaccacucca aggaccccgg cgcccucaug      720

uuccccaucu acaccuacac cggcaagucc cacuucaugc uccccgacga cgacguccag      780

ggcauccagu cccucuacgg ccccggcgac gaggacccca accccaagca ccccaagacc      840

cccgacaagu gcgaccccuc ccucucccuc gacgccauca ccucccuccg cggcgagacc      900

augaucuuca aggaccgcuu cuucuggcgc cuccaccccc agcaggucga cgccgagcuc      960

uuccucacca aguccuucug gcccgagcuc cccaaccgca ucgacgccgc cuacgagcac     1020

cccucccacg accucaucuu caucuuccgc ggccgcaagu ucugggcccu caacggcuac     1080

gacauccucg agggcuaccc caagaagauc uccgagcucg gccuccccaa ggaggucaag     1140

aagaucuccg ccgccgucca cuucgaggac accggcaaga cccuccucuu cuccggcaac     1200

caggucuggc gcuacgacga caccaaccac aucauggaca aggacuaccc ccgccucauc     1260

gaggaggacu uccccggcau cggcgacaag gucgacgccg ucuacgagaa gaacggcuac     1320

aucuacuucu ucaacggccc cauccaguuc gaguacucca ucugguccaa ccgcaucguc     1380

cgcgucaugc ccgccaacuc cauccucugg ugcuga                               1416


<210>  388
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  388
auggagaccc ccaacaccac cgaggacuac gacaccacca ccgaguucga cuacggcgac       60

gccacccccu gccagaaggu caacgagcgc gccuucggcg cccagcuccu ccccccccuc      120

uacucccucg ucuucgucau cggccucguc ggcaacaucc ucgucguccu cguccucguc      180

caguacaagc gccucaagaa caugaccucc aucuaccucc ucaaccucgc caucuccgac      240

cuccucuucc ucuucacccu ccccuucugg aucgacuaca agcucaagga cgacuggguc      300

uucggcgacg ccaugugcaa gauccucucc ggcuucuacu acaccggccu cuacuccgag      360

aucuucuuca ucauccuccu caccaucgac cgcuaccucg ccaucgucca cgccgucuuc      420

gcccuccgcg cccgcaccgu caccuucggc gucaucaccu ccaucaucau cugggcccuc      480

gccauccucg ccuccaugcc cggccucuac uucuccaaga cccaguggga guucacccac      540

cacaccugcu cccuccacuu cccccacgag ucccuccgcg aguggaagcu cuuccaggcc      600

cucaagcuca accucuucgg ccucguccuc ccccuccucg ucaugaucau cugcuacacc      660

ggcaucauca agauccuccu ccgccgcccc aacgagaaga aguccaaggc cguccgccuc      720

aucuucguca ucaugaucau cuucuuccuc uucuggaccc ccuacaaccu caccauccuc      780

aucuccgucu uccaggacuu ccucuucacc cacgagugcg agcagucccg ccaccucgac      840

cucgccgucc aggucaccga ggucaucgcc uacacccacu gcugcgucaa ccccgucauc      900

uacgccuucg ucggcgagcg cuuccgcaag uaccuccgcc agcucuucca ccgccgcguc      960

gccguccacc ucgucaagug gcuccccuuc cucuccgucg accgccucga gcgcgucucc     1020

uccaccuccc ccuccaccgg cgagcacgag cucuccgccg gcuucuga                  1068


<210>  389
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  389
augcgcaccc ucgccugccu ccuccuccuc ggcugcggcu accucgccca cguccucgcc       60

gaggaggccg agaucccccg cgaggucauc gagcgccucg cccgcuccca gauccacucc      120

auccgcgacc uccagcgccu ccucgagauc gacuccgucg gcuccgagga cucccucgac      180

accucccucc gcgcccacgg cguccacgcc accaagcacg uccccgagaa gcgcccccuc      240

cccauccgcc gcaagcgcuc caucgaggag gccguccccg ccgucugcaa gacccgcacc      300

gucaucuacg agaucccccg cucccagguc gaccccaccu ccgccaacuu ccucaucugg      360

ccccccugcg ucgaggucaa gcgcugcacc ggcugcugca acaccuccuc cgucaagugc      420

cagcccuccc gcguccacca ccgcuccguc aaggucgcca aggucgagua cguccgcaag      480

aagcccaagc ucaaggaggu ccagguccgc cucgaggagc accucgagug cgccugcgcc      540

accaccuccc ucaaccccga cuaccgcgag gaggacaccg gccgcccccg cgaguccggc      600

aagaagcgca agcgcaagcg ccucaagccc accuga                                636


<210>  390
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  390
augaaccgcu gcugggcccu cuuccucucc cucugcugcu accuccgccu cgucuccgcc       60

gagggcgacc ccauccccga ggagcucuac gagaugcucu ccgaccacuc cauccgcucc      120

uucgacgacc uccagcgccu ccuccacggc gaccccggcg aggaggacgg cgccgagcuc      180

gaccucaaca ugacccgcuc ccacuccggc ggcgagcucg agucccucgc ccgcggccgc      240

cgcucccucg gcucccucac caucgccgag cccgccauga ucgccgagug caagacccgc      300

accgaggucu ucgagaucuc ccgccgccuc aucgaccgca ccaacgccaa cuuccucguc      360

uggccccccu gcgucgaggu ccagcgcugc uccggcugcu gcaacaaccg caacguccag      420

ugccgcccca cccaggucca gcuccgcccc guccaggucc gcaagaucga gaucguccgc      480

aagaagccca ucuucaagaa ggccaccguc acccucgagg accaccucgc cugcaagugc      540

gagaccgucg ccgccgcccg ccccgucacc cgcucccccg gcggcuccca ggagcagcgc      600

gccaagaccc cccagacccg cgucaccauc cgcaccgucc gcguccgccg cccccccaag      660

ggcaagcacc gcaaguucaa gcacacccac gacaagaccg cccucaagga gacccucggc      720

gccuga                                                                 726


<210>  391
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  391
augucccucu ucggccuccu ccuccucacc uccgcccucg ccggccagcg ccagggcacc       60

caggccgagu ccaaccucuc cuccaaguuc caguucuccu ccaacaagga gcagaacggc      120

guccaggacc cccagcacga gcgcaucauc accgucucca ccaacggcuc cauccacucc      180

ccccgcuucc cccacaccua cccccgcaac accguccucg ucuggcgccu cgucgccguc      240

gaggagaacg ucuggaucca gcucaccuuc gacgagcgcu ucggccucga ggaccccgag      300

gacgacaucu gcaaguacga cuucgucgag gucgaggagc ccuccgacgg caccauccuc      360

ggccgcuggu gcggcuccgg caccgucccc ggcaagcaga ucuccaaggg caaccagauc      420

cgcauccgcu ucgucuccga cgaguacuuc cccuccgagc ccggcuucug cauccacuac      480

aacaucguca ugccccaguu caccgaggcc gucucccccu ccguccuccc ccccuccgcc      540

cucccccucg accuccucaa caacgccauc accgccuucu ccacccucga ggaccucauc      600

cgcuaccucg agcccgagcg cuggcagcuc gaccucgagg accucuaccg ccccaccugg      660

cagcuccucg gcaaggccuu cgucuucggc cgcaaguccc gcgucgucga ccucaaccuc      720

cucaccgagg agguccgccu cuacuccugc accccccgca acuucuccgu cuccauccgc      780

gaggagcuca agcgcaccga caccaucuuc uggcccggcu gccuccucgu caagcgcugc      840

ggcggcaacu gcgccugcug ccuccacaac ugcaacgagu gccagugcgu ccccuccaag      900

gucaccaaga aguaccacga gguccuccag cuccgcccca agaccggcgu ccgcggccuc      960

cacaaguccc ucaccgacgu cgcccucgag caccacgagg agugcgacug cgucugccgc     1020

ggcuccaccg gcggcuga                                                   1038


<210>  392
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  392
augcaccgcc ucaucuucgu cuacacccuc aucugcgcca acuucugcuc cugccgcgac       60

accuccgcca ccccccaguc cgccuccauc aaggcccucc gcaacgccaa ccuccgccgc      120

gacgaccucu accgccgcga cgagaccauc caggucaagg gcaacggcua cguccagucc      180

ccccgcuucc ccaacuccua cccccgcaac cuccuccuca ccuggcgccu ccacucccag      240

gagaacaccc gcauccagcu cgucuucgac aaccaguucg gccucgagga ggccgagaac      300

gacaucugcc gcuacgacuu cgucgagguc gaggacaucu ccgagaccuc caccaucauc      360

cgcggccgcu ggugcggcca caaggagguc cccccccgca ucaagucccg caccaaccag      420

aucaagauca ccuucaaguc cgacgacuac uucgucgcca agcccggcuu caagaucuac      480

uacucccucc ucgaggacuu ccagcccgcc gccgccuccg agaccaacug ggaguccguc      540

accuccucca ucuccggcgu cuccuacaac ucccccuccg ucaccgaccc cacccucauc      600

gccgacgccc ucgacaagaa gaucgccgag uucgacaccg ucgaggaccu ccucaaguac      660

uucaaccccg aguccuggca ggaggaccuc gagaacaugu accucgacac cccccgcuac      720

cgcggccgcu ccuaccacga ccgcaagucc aaggucgacc ucgaccgccu caacgacgac      780

gccaagcgcu acuccugcac cccccgcaac uacuccguca acauccgcga ggagcucaag      840

cucgccaacg ucgucuucuu cccccgcugc cuccucgucc agcgcugcgg cggcaacugc      900

ggcugcggca ccgucaacug gcgcuccugc accugcaacu ccggcaagac cgucaagaag      960

uaccacgagg uccuccaguu cgagcccggc cacaucaagc gccgcggccg cgccaagacc     1020

auggcccucg ucgacaucca gcucgaccac cacgagcgcu gcgacugcau cugcuccucc     1080

cgcccccccc gcuga                                                      1095


<210>  393
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  393
auggucaccc acuccaaguu ccccgccgcc ggcauguccc gcccccucga caccucccuc       60

cgccucaaga ccuucuccuc caaguccgag uaccagcucg ucgucaacgc cguccgcaag      120

cuccaggagu ccggcuucua cugguccgcc gucaccggcg gcgaggccaa ccuccuccuc      180

uccgccgagc ccgccggcac cuuccucauc cgcgacuccu ccgaccagcg ccacuucuuc      240

acccucuccg ucaagaccca guccggcacc aagaaccucc gcauccagug cgagggcggc      300

uccuucuccc uccaguccga cccccgcucc acccagcccg ucccccgcuu cgacugcguc      360

cucaagcucg uccaccacua caugcccccc cccggcgccc ccuccuuccc cucccccccc      420

accgagcccu ccuccgaggu ccccgagcag cccuccgccc agccccuccc cggcuccccc      480

ccccgccgcg ccuacuacau cuacuccggc ggcgagaaga ucccccucgu ccucucccgc      540

ccccucuccu ccaacgucgc cacccuccag caccucugcc gcaagaccgu caacggccac      600

cucgacuccu acgagaaggu cacccagcuc cccggcccca uccgcgaguu ccucgaccag      660

uacgacgccc cccucuga                                                    678


<210>  394
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  394
augguccccu ccgccggcca gcucgcccuc uucgcccucg gcaucguccu cgccgccugc       60

caggcccucg agaacuccac cuccccccuc uccgccgacc cccccgucgc cgccgccguc      120

gucucccacu ucaacgacug ccccgacucc cacacccagu ucugcuucca cggcaccugc      180

cgcuuccucg uccaggagga caagcccgcc ugcgucugcc acuccggcua cgucggcgcc      240

cgcugcgagc acgccgaccu ccucgccguc gucgccgccu cccagaagaa gcaggccauc      300

accgcccucg ucgucgucuc caucgucgcc cucgccgucc ucaucaucac cugcguccuc      360

auccacugcu gccagguccg caagcacugc gaguggugcc gcgcccucau cugccgccac      420

gagaagcccu ccgcccuccu caagggccgc accgccugcu gccacuccga gaccgucguc      480

uga                                                                    483


<210>  395
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  395
augccccccu ccggccuccg ccuccucccc cuccuccucc cccuccucug gcuccucguc       60

cucacccccg gccgccccgc cgccggccuc uccaccugca agaccaucga cauggagcuc      120

gucaagcgca agcgcaucga ggccauccgc ggccagaucc ucuccaagcu ccgccucgcc      180

uccccccccu cccagggcga gguccccccc ggcccccucc ccgaggccgu ccucgcccuc      240

uacaacucca cccgcgaccg cgucgccggc gaguccgccg agcccgagcc cgagcccgag      300

gccgacuacu acgccaagga ggucacccgc guccucaugg ucgagaccca caacgagauc      360

uacgacaagu ucaagcaguc cacccacucc aucuacaugu ucuucaacac cuccgagcuc      420

cgcgaggccg uccccgagcc cguccuccuc ucccgcgccg agcuccgccu ccuccgccuc      480

aagcucaagg ucgagcagca cgucgagcuc uaccagaagu acuccaacaa cuccuggcgc      540

uaccucucca accgccuccu cgcccccucc gacucccccg aguggcucuc cuucgacguc      600

accggcgucg uccgccagug gcucucccgc ggcggcgaga ucgagggcuu ccgccucucc      660

gcccacugcu ccugcgacuc ccgcgacaac acccuccagg ucgacaucaa cggcuucacc      720

accggccgcc gcggcgaccu cgccaccauc cacggcauga accgccccuu ccuccuccuc      780

auggccaccc cccucgagcg cgcccagcac cuccaguccu cccgccaccg ccgcgcccuc      840

gacaccaacu acugcuucuc cuccaccgag aagaacugcu gcguccgcca gcucuacauc      900

gacuuccgca aggaccucgg cuggaagugg auccacgagc ccaagggcua ccacgccaac      960

uucugccucg gccccugccc cuacaucugg ucccucgaca cccaguacuc caagguccuc     1020

gcccucuaca accagcacaa ccccggcgcc uccgccgccc ccugcugcgu cccccaggcc     1080

cucgagcccc uccccaucgu cuacuacguc ggccgcaagc ccaaggucga gcagcucucc     1140

aacaugaucg uccgcuccug caagugcucc uga                                  1173


<210>  396
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  396
augcacuacu gcguccucuc cgccuuccuc auccuccacc ucgucaccgu cgcccucucc       60

cucuccaccu gcuccacccu cgacauggac caguucaugc gcaagcgcau cgaggccauc      120

cgcggccaga uccucuccaa gcucaagcuc accucccccc ccgaggacua ccccgagccc      180

gaggaggucc cccccgaggu caucuccauc uacaacucca cccgcgaccu ccuccaggag      240

aaggccuccc gccgcgccgc cgccugcgag cgcgagcgcu ccgacgagga guacuacgcc      300

aaggaggucu acaagaucga caugcccccc uucuuccccu ccgagaacgc cauccccccc      360

accuucuacc gccccuacuu ccgcaucguc cgcuucgacg ucuccgccau ggagaagaac      420

gccuccaacc ucgucaaggc cgaguuccgc gucuuccgcc uccagaaccc caaggcccgc      480

guccccgagc agcgcaucga gcucuaccag auccucaagu ccaaggaccu caccuccccc      540

acccagcgcu acaucgacuc caaggucguc aagacccgcg ccgagggcga guggcucucc      600

uucgacguca ccgacgccgu ccacgagugg cuccaccaca aggaccgcaa ccucggcuuc      660

aagaucuccc uccacugccc cugcugcacc uucguccccu ccaacaacua caucaucccc      720

aacaaguccg aggagcucga ggcccgcuuc gccggcaucg acggcaccuc caccuacacc      780

uccggcgacc agaagaccau caaguccacc cgcaagaaga acuccggcaa gaccccccac      840

cuccuccuca ugcuccuccc cuccuaccgc cucgaguccc agcagaccaa ccgccgcaag      900

aagcgcgccc ucgacgccgc cuacugcuuc cgcaacgucc aggacaacug cugccuccgc      960

ccccucuaca ucgacuucaa gcgcgaccuc ggcuggaagu ggauccacga gcccaagggc     1020

uacaacgcca acuucugcgc cggcgccugc cccuaccucu gguccuccga cacccagcac     1080

ucccgcgucc ucucccucua caacaccauc aaccccgagg ccuccgccuc ccccugcugc     1140

gucucccagg accucgagcc ccucaccauc cucuacuaca ucggcaagac ccccaagauc     1200

gagcagcucu ccaacaugau cgucaagucc ugcaagugcu ccuga                     1245


<210>  397
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  397
augaagaugc accuccagcg cgcccucguc guccucgccc uccucaacuu cgccaccguc       60

ucccucuccc ucuccaccug caccacccuc gacuucggcc acaucaagaa gaagcgcguc      120

gaggccaucc gcggccagau ccucuccaag cuccgccuca ccuccccccc cgagcccacc      180

gucaugaccc acguccccua ccagguccuc gcccucuaca acuccacccg cgagcuccuc      240

gaggagaugc acggcgagcg cgaggagggc ugcacccagg agaacaccga guccgaguac      300

uacgccaagg agauccacaa guucgacaug auccagggcc ucgccgagca caacgagcuc      360

gccgucugcc ccaagggcau caccuccaag gucuuccgcu ucaacgucuc cuccgucgag      420

aagaaccgca ccaaccucuu ccgcgccgag uuccgcgucc uccgcguccc caaccccucc      480

uccaagcgca acgagcagcg caucgagcuc uuccagaucc uccgccccga cgagcacauc      540

gccaagcagc gcuacaucgg cggcaagaac cuccccaccc gcggcaccgc cgaguggcuc      600

uccuucgacg ucaccgacac cguccgcgag uggcuccucc gccgcgaguc caaccucggc      660

cucgagaucu ccauccacug ccccugccac accuuccagc ccaacggcga cauccucgag      720

aacauccacg aggucaugga gaucaaguuc aagggcgucg acaacgagga cgaccacggc      780

cgcggcgacc ucggccgccu caagaagcag aaggaccacc acaaccccca ccucauccuc      840

augaugaucc ccccccaccg ccucgacaac cccggccagg gcggccagcg caagaagcgc      900

gcccucgaca ccaacuacug cuuccgcaac cucgaggaga acugcugcgu ccgcccccuc      960

uacaucgacu uccgccagga ccucggcugg aagugggucc acgagcccaa gggcuacuac     1020

gccaacuucu gcuccggccc cugccccuac cuccgcuccg ccgacaccac ccacuccacc     1080

guccucggcc ucuacaacac ccucaacccc gaggccuccg ccucccccug cugcgucccc     1140

caggaccucg agccccucac cauccucuac uacgucggcc gcacccccaa ggucgagcag     1200

cucuccaaca uggucgucaa guccugcaag ugcuccuga                            1239


<210>  398
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  398
auggcccccg ucgccgucug ggccgcccuc gccgucggcc ucgagcucug ggccgccgcc       60

cacgcccucc ccgcccaggu cgccuucacc cccuacgccc ccgagcccgg cuccaccugc      120

cgccuccgcg aguacuacga ccagaccgcc cagaugugcu gcuccaagug cucccccggc      180

cagcacgcca aggucuucug caccaagacc uccgacaccg ucugcgacuc cugcgaggac      240

uccaccuaca cccagcucug gaacuggguc cccgagugcc ucuccugcgg cucccgcugc      300

uccuccgacc aggucgagac ccaggccugc acccgcgagc agaaccgcau cugcaccugc      360

cgccccggcu gguacugcgc ccucuccaag caggagggcu gccgccucug cgccccccuc      420

cgcaagugcc gccccggcuu cggcgucgcc cgccccggca ccgagaccuc cgacgucguc      480

ugcaagcccu gcgcccccgg caccuucucc aacaccaccu ccuccaccga caucugccgc      540

ccccaccaga ucugcaacgu cgucgccauc cccggcaacg ccuccaugga cgccgucugc      600

accuccaccu cccccacccg cuccauggcc cccggcgccg uccaccuccc ccagcccguc      660

uccacccgcu cccagcacac ccagcccacc cccgagcccu ccaccgcccc cuccaccucc      720

uuccuccucc ccaugggccc cucccccccc gccgagggcu ccaccggcga cuucgcccuc      780

cccgucggcc ucaucgucgg cgucaccgcc cucggccucc ucaucaucgg cgucgucaac      840

ugcgucauca ugacccaggu caagaagaag ccccucugcc uccagcgcga ggccaagguc      900

ccccaccucc ccgccgacaa ggcccgcggc acccagggcc ccgagcagca gcaccuccuc      960

aucaccgccc ccuccuccuc cuccuccucc cucgaguccu ccgccuccgc ccucgaccgc     1020

cgcgccccca cccgcaacca gccccaggcc cccggcgucg aggccuccgg cgccggcgag     1080

gcccgcgccu ccaccggcuc cuccgacucc ucccccggcg gccacggcac ccaggucaac     1140

gucaccugca ucgucaacgu cugcuccucc uccgaccacu ccucccagug cuccucccag     1200

gccuccucca ccaugggcga caccgacucc ucccccuccg agucccccaa ggacgagcag     1260

guccccuucu ccaaggagga gugcgccuuc cgcucccagc ucgagacccc cgagacccuc     1320

cucggcucca ccgaggagaa gccccucccc cucggcgucc ccgacgccgg caugaagccc     1380

uccuga                                                                1386


<210>  399
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  399
augcccguca ugcgccucuu ccccugcuuc cuccagcucc ucgccggccu cgcccucccc       60

gccguccccc cccagcagug ggcccucucc gccggcaacg gcuccuccga ggucgagguc      120

guccccuucc aggaggucug gggccgcucc uacugccgcg cccucgagcg ccucgucgac      180

gucgucuccg aguaccccuc cgaggucgag cacauguucu cccccuccug cgucucccuc      240

cuccgcugca ccggcugcug cggcgacgag aaccuccacu gcguccccgu cgagaccgcc      300

aacgucacca ugcagcuccu caagauccgc uccggcgacc gccccuccua cgucgagcuc      360

accuucuccc agcacguccg cugcgagugc cgcccccucc gcgagaagau gaagcccgag      420

cgccgccgcc ccaagggccg cggcaagcgc cgccgcgaga agcagcgccc caccgacugc      480

caccucugcg gcgacgccgu cccccgccgc uga                                   513


<210>  400
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  400
augaccgacc gccagaccga caccgccccc ucccccuccu accaccuccu ccccggccgc       60

cgccgcaccg ucgacgccgc cgccucccgc ggccagggcc ccgagcccgc ccccggcggc      120

ggcgucgagg gcgucggcgc ccgcggcguc gcccucaagc ucuucgucca gcuccucggc      180

ugcucccgcu ucggcggcgc cgucguccgc gccggcgagg ccgagcccuc cggcgccgcc      240

cgcuccgccu ccuccggccg cgaggagccc cagcccgagg agggcgagga ggaggaggag      300

aaggaggagg agcgcggccc ccaguggcgc cucggcgccc gcaagcccgg cuccuggacc      360

ggcgaggccg ccgucugcgc cgacuccgcc cccgccgccc gcgcccccca ggcccucgcc      420

cgcgccuccg gccgcggcgg ccgcgucgcc cgccgcggcg ccgaggaguc cggccccccc      480

cacucccccu cccgccgcgg cuccgccucc cgcgccggcc ccggccgcgc cuccgagacc      540

augaacuucc uccucuccug gguccacugg ucccucgccc uccuccucua ccuccaccac      600

gccaaguggu cccaggccgc ccccauggcc gagggcggcg gccagaacca ccacgagguc      660

gucaaguuca uggacgucua ccagcgcucc uacugccacc ccaucgagac ccucgucgac      720

aucuuccagg aguaccccga cgagaucgag uacaucuuca agcccuccug cgucccccuc      780

augcgcugcg gcggcugcug caacgacgag ggccucgagu gcguccccac cgaggagucc      840

aacaucacca ugcagaucau gcgcaucaag ccccaccagg gccagcacau cggcgagaug      900

uccuuccucc agcacaacaa gugcgagugc cgccccaaga aggaccgcgc ccgccaggag      960

aagaaguccg uccgcggcaa gggcaagggc cagaagcgca agcgcaagaa gucccgcuac     1020

aaguccuggu ccgucuacgu cggcgcccgc ugcugccuca ugcccugguc ccuccccggc     1080

ccccaccccu gcggccccug cuccgagcgc cgcaagcacc ucuucgucca ggacccccag     1140

accugcaagu gcuccugcaa gaacaccgac ucccgcugca aggcccgcca gcucgagcuc     1200

aacgagcgca ccugccgcug cgacaagccc cgccgcuga                            1239


<210>  401
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  401
augaacuucc uccucuccug gguccacugg ucccucgccc uccuccucua ccuccaccac       60

gccaaguggu cccaggccgc ccccauggcc gagggcggcg gccagaacca ccacgagguc      120

gucaaguuca uggacgucua ccagcgcucc uacugccacc ccaucgagac ccucgucgac      180

aucuuccagg aguaccccga cgagaucgag uacaucuuca agcccuccug cgucccccuc      240

augcgcugcg gcggcugcug caacgacgag ggccucgagu gcguccccac cgaggagucc      300

aacaucacca ugcagaucau gcgcaucaag ccccaccagg gccagcacau cggcgagaug      360

uccuuccucc agcacaacaa gugcgagugc cgccccaaga aggaccgcgc ccgccaggag      420

aagaaguccg uccgcggcaa gggcaagggc cagaagcgca agcgcaagaa gucccgcuac      480

aaguccuggu ccgucuacgu cggcgcccgc ugcugccuca ugcccugguc ccuccccggc      540

ccccaccccu gcggccccug cuccgagcgc cgcaagcacc ucuucgucca ggacccccag      600

accugcaagu gcuccugcaa gaacaccgac ucccgcugca aggcccgcca gcucgagcuc      660

aacgagcgca ccugccgcug cgacaagccc cgccgcuga                             699


<210>  402
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  402
augucccccc uccuccgccg ccuccuccuc gccgcccucc uccagcucgc ccccgcccag       60

gcccccgucu cccagcccga cgcccccggc caccagcgca aggucgucuc cuggaucgac      120

gucuacaccc gcgccaccug ccagccccgc gaggucgucg ucccccucac cgucgagcuc      180

augggcaccg ucgccaagca gcucgucccc uccugcguca ccguccagcg cugcggcggc      240

ugcugccccg acgacggccu cgagugcguc cccaccggcc agcaccaggu ccgcaugcag      300

auccucauga uccgcuaccc cuccucccag cucggcgaga ugucccucga ggagcacucc      360

cagugcgagu gccgccccaa gaagaaggac uccgccguca agcccgaccg cgccgccacc      420

ccccaccacc gcccccagcc ccgcuccguc cccggcuggg acuccgcccc cggcgccccc      480

ucccccgccg acaucaccca ccccaccccc gcccccggcc ccuccgccca cgccgccccc      540

uccaccaccu ccgcccucac ccccggcccc gccgccgccg ccgccgacgc cgccgccucc      600

uccgucgcca agggcggcgc cuga                                             624


<210>  403
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  403
augcaccucc ucggcuucuu cuccgucgcc ugcucccucc ucgccgccgc ccuccucccc       60

ggcccccgcg aggcccccgc cgccgccgcc gccuucgagu ccggccucga ccucuccgac      120

gccgagcccg acgccggcga ggccaccgcc uacgccucca aggaccucga ggagcagcuc      180

cgcuccgucu ccuccgucga cgagcucaug accguccucu accccgagua cuggaagaug      240

uacaagugcc agcuccgcaa gggcggcugg cagcacaacc gcgagcaggc caaccucaac      300

ucccgcaccg aggagaccau caaguucgcc gccgcccacu acaacaccga gauccucaag      360

uccaucgaca acgaguggcg caagacccag ugcaugcccc gcgaggucug caucgacguc      420

ggcaaggagu ucggcgucgc caccaacacc uucuucaagc cccccugcgu cuccgucuac      480

cgcugcggcg gcugcugcaa cuccgagggc cuccagugca ugaacaccuc caccuccuac      540

cucuccaaga cccucuucga gaucaccguc ccccucuccc agggccccaa gcccgucacc      600

aucuccuucg ccaaccacac cuccugccgc ugcaugucca agcucgacgu cuaccgccag      660

guccacucca ucauccgccg cucccucccc gccacccucc cccagugcca ggccgccaac      720

aagaccugcc ccaccaacua cauguggaac aaccacaucu gccgcugccu cgcccaggag      780

gacuucaugu ucuccuccga cgccggcgac gacuccaccg acggcuucca cgacaucugc      840

ggccccaaca aggagcucga cgaggagacc ugccagugcg ucugccgcgc cggccuccgc      900

cccgccuccu gcggccccca caaggagcuc gaccgcaacu ccugccagug cgucugcaag      960

aacaagcucu uccccuccca gugcggcgcc aaccgcgagu ucgacgagaa caccugccag     1020

ugcgucugca agcgcaccug cccccgcaac cagccccuca accccggcaa gugcgccugc     1080

gagugcaccg agucccccca gaagugccuc cucaagggca agaaguucca ccaccagacc     1140

ugcuccugcu accgccgccc cugcaccaac cgccagaagg ccugcgagcc cggcuucucc     1200

uacuccgagg aggucugccg cugcgucccc uccuacugga agcgccccca gauguccuga     1260


<210>  404
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  404
auguaccgcg agugggucgu cgucaacguc uucaugaugc ucuacgucca gcucguccag       60

ggcuccucca acgagcacgg ccccgucaag cgcuccuccc aguccacccu cgagcgcucc      120

gagcagcaga uccgcgccgc cuccucccuc gaggagcucc uccgcaucac ccacuccgag      180

gacuggaagc ucuggcgcug ccgccuccgc cucaaguccu ucaccuccau ggacucccgc      240

uccgccuccc accgcuccac ccgcuucgcc gccaccuucu acgacaucga gacccucaag      300

gucaucgacg aggaguggca gcgcacccag ugcucccccc gcgagaccug cgucgagguc      360

gccuccgagc ucggcaaguc caccaacacc uucuucaagc cccccugcgu caacgucuuc      420

cgcugcggcg gcugcugcaa cgaggagucc cucaucugca ugaacaccuc caccuccuac      480

aucuccaagc agcucuucga gaucuccguc ccccucaccu ccguccccga gcucgucccc      540

gucaaggucg ccaaccacac cggcugcaag ugccucccca ccgccccccg ccaccccuac      600

uccaucaucc gccgcuccau ccagaucccc gaggaggacc gcugcuccca cuccaagaag      660

cucugcccca ucgacaugcu cugggacucc aacaagugca agugcguccu ccaggaggag      720

aacccccucg ccggcaccga ggaccacucc caccuccagg agcccgcccu cugcggcccc      780

cacaugaugu ucgacgagga ccgcugcgag ugcgucugca agacccccug ccccaaggac      840

cucauccagc accccaagaa cugcuccugc uucgagugca aggagucccu cgagaccugc      900

ugccagaagc acaagcucuu ccaccccgac accugcuccu gcgaggaccg cugccccuuc      960

cacacccgcc ccugcgccuc cggcaagacc gccugcgcca agcacugccg cuuccccaag     1020

gagaagcgcg ccgcccaggg cccccacucc cgcaagaacc ccuga                     1065


<210>  405
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  405
auggccguga uggcucccag aacccugguc cuccuucuga gcggcgcauu ggccuuaaca       60

cagacuuggg cg                                                           72


<210>  406
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  406
auggacgcca ugaagagagg ccugugcugu gugcuccuuc ugugcggggc ugucuucguu       60

agccccucc                                                               69


<210>  407
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  407
augggcgugc acgagugccc cgccuggcug uggcuccuuc ugagcuuguu aucccugccu       60

cuagggcucc caguccuggg a                                                 81


<210>  408
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  408
augaaguggg ugaccuucau cagccugcuc uuucuuuucu ccucugccua cuca             54


<210>  409
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from 
       Artificial____cleavage site-Furin

<400>  409
agaaggcggc gcaagcga                                                     18


<210>  410
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  410
auggacagcg augagaccgg cuucgaacac uccgggcugu gggugucugu ccucgccgga       60

cuucuguugg gugcuugcca ggcacauccc aucccugacu caaguccauu acugcaauuu      120

ggcgggcagg uuagacagag guaccuauau acagaugacg cccagcaaac ugaggcgcac      180

cucgaaauuc gggaggaugg aacggugggc ggugcugccg accagagccc ggaaucccug      240

cuucagcuga aggcauugaa acccggggua auacagaucc ucggagugaa gaccucucgc      300

uuccuguguc aacgaccuga uggcgcccug uacggcucgc uccauuuuga cccagaggcu      360

ugcucauucc gugaguuacu gcuugaagau ggguauaacg ucuaccagag cgaggcacac      420

ggauugcccc ugcaucuacc ugguaauaaa aguccacaca gagaccccgc cccuaggggc      480

ccagcucggu uucucccgcu gcccgggcuu ccuccagccc ugcccgaacc uccaggaauu      540

uuggcgcccc agccgccuga ugugggcucc ucugaccccc ucagcauggu ugguccaucc      600

caggggcgcu caccuaguua ugcaagcuga                                       630


<210>  411
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  411
augcacagcu uucccccucu gcuccuucug uuguucuggg gcguggucuc ccauucuuuc       60

ccagccaccu uagagacaca ggaacaagac guugaucugg ugcagaagua ccuagagaaa      120

uauuacaacc ucaagaauga cgggagacag guagagaaaa ggcggaacuc aggaccggug      180

gucgaaaagc ugaaacagau gcaagaauuu uucggucuua aggugacugg caagcccgau      240

gcugagacgc ugaaaguuau gaagcagccu cgcugcgggg ugccagacgu cgcacaguuu      300

guguugaccg agggaaaucc ccgaugggaa cagacacacc ucacuuaucg uaucgagaac      360

uacaccccug aucugccaag agccgacgua gaucaugcga uugaaaaggc uuuccaacug      420

uggaguaaug uuacaccccu caccuuuacu aaagugagcg agggccaggc cgacauaaug      480

aucuccuucg ucagggguga ucaccgggac aacucuccuu uugaugggcc aggaggcaau      540

uuagcacaug ccuuccagcc gggccccggg auuggaggug acgcucacuu ugaugaggac      600

gaacgcugga caaacaauuu cagagaguau aaccugcaca ggguggcagc ccaugaacuu      660

ggccacucgu uggggcuguc acauagcacc gacaucggag cucuaaugua cccuaguuau      720

acguuuuccg gcgaugugca gcucgcccaa gacgauauug acgguaucca ggcgauauac      780

gggcggucuc agaauccagu ccaacccauc ggaccucaga cuccaaaagc augugauagc      840

aagcugaccu ucgacgccau uacaacuauc cgcggcgagg uuauguucuu uaaggaucga      900

uucuacauga gaaccaaccc cuuuuauccg gaaguggagc uuaauuucau uuccguauuu      960

uggccucagc ugcccaacgg cuuggaggcu gccuacgagu ucgcagacag ggaugaagug     1020

cgguuuuuca aagggaauaa guauugggcu guccagggac aaaacgugcu ccacgguuac     1080

ccaaaagaca ucuauucaag uuuuggcuuc ccucguacag uuaagcacau agaugccgcg     1140

cugagcgaag agaacaccgg gaaaacguac uuuuucgugg ccaauaagua uuggcgcuac     1200

gacgaauaca aaagaucuau ggaccccgga uauccaaaga ugauugcaca ugauuuuccc     1260

ggcaucgguc acaaggucga cgcuguguuc augaaagaug gguucuuuua cuucuuucau     1320

ggcacuaggc aguauaaguu cgacccuaaa acaaagcgga uuuuaacccu gcagaaagcc     1380

aacuccuggu uuaauugccg aaagaacuga                                      1410


<210>  412
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  412
augcacagcu uucccccucu gcuccuucug uuguucuggg gcguggucuc ccauucuuuc       60

guuuuaaccg aggggaaccc aagaugggaa cagacacacc ugacuuacag gaucgagaau      120

uauacgccgg accuaccccg ggccgaugug gaccaugcua uugaaaaggc auuucaacuc      180

uggucaaacg uaaccccucu gacauucacu aaagugagug agggacaggc cgauauaaug      240

aucagcuuug uccgcgguga ccaccgagau aauuccccau ucgacggccc cgggggaaac      300

cuugcgcaug cuuuucagcc uggcccaggu auugggggag augcccacuu cgacgaagau      360

gagcguugga ccaauaacuu uagagaguac aaucugcaca ggguggcagc ccaugaauug      420

ggccacucuc ucggccuguc gcauucaaca gacaucgggg cucugaugua ucccagcuac      480

accuucagug gagauguuca gcucgcacaa gacgauauug acgguaucca ggccauauau      540

ggccgguccc agaacccugu gcagccaauc gggccgcaaa cucccaaggc uugcgacucu      600

aaauuaacau uugaugccau uaccacgauc cgcggagagg ucauguucuu uaaggacaga      660

uucuacauga ggacuaaucc uuucuaucca gaaguggagc ugaacuuuau uagcguauuc      720

uggccccagc uuccuaaugg cuuggaggcg gcauacgaau uugccgaucg ggacgagguu      780

cgcuucuuua aagguaacaa guacugggcu gugcaggggc agaauguccu gcacggauau      840

ccaaaggaua ucuacuccuc auucggcuuu ccccgaaccg ugaaacacau agacgccgca      900

cuaagugaag agaacacagg caagacuuau uucuuugugg cuaauaaaua cuggagauau      960

gaugaauaca agaggagcau ggacccgggg uauccuaaaa ugauugccca ugauuucccc     1020

ggaaucgguc acaaggucga cgcgguuuuu augaaggaug gcuucuuuua cuucuuccau     1080

gggacccggc aauacaaauu ugacccaaag acaaaacgua uucucacccu gcagaaggcc     1140

aacucuuggu ucaacugucg caaaaauuga                                      1170


<210>  413
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  413
augaagaaaa acauccugaa gauucucaug gacagcuacu ccaaagaguc uaagauacag       60

accgugagaa gggucacauc aguuagucuu cuggccgugu auuugacuau gaauacgagc      120

uccuuaguac uggcuaaacc caucgaaaac accaaugaua caucuauuaa gaacguggag      180

aagcuacgga augcaccuaa cgaagaaaau ucgaaaaagg ucgaagacuc aaagaacgau      240

aagguggagc acguuaaaaa uaucgaggaa gccaaggugg agcaagucgc gccagaagua      300

aagagcaaaa guacucuccg cuccgcuucu auugccaaca ccaauagcga gaaguacgac      360

uucgaguauc ugaacggccu uuccuacaca gaacugacca auuugaucaa aaacauaaag      420

uggaaucaga ucaacgggcu cuuuaacuau ucaacuggaa gucagaaauu cuuuggugau      480

aagaaucgag ugcaggcaau uaucaacgcc cugcaagaga gcggccguac auacaccgcu      540

aaugacauga aagggauuga aacguucacu gagguucuga gagcaggauu uuaucucggc      600

uacuacaacg augguuuauc uuaucugaau gacaggaacu uccaggauaa gugcaucccg      660

gccaugauag cuauucagaa gaaucccaac uuuaaacuug ggaccgccgu gcaggacgaa      720

gucaucacau ccuugggaaa gcugauuggc aaugcgucag caaacgccga gguggugaau      780

aacugugucc cuguucuaaa acaauuccgg gagaaucuca accaguacgc uccagauuau      840

gugaagggca cugccguaaa ugaacugauc aaagggaucg aguuugacuu cagcggagca      900

gcuuacgaaa aggaugugaa gaccaugccc ugguauggua aaauugaccc uuuuauaaac      960

gagcuuaagg cccugggcuu guacgggaac aucacaagug cgaccgaaug ggccucugac     1020

gucggaauuu auuaccucuc caaauucggc cuguacagca cgaaucgcaa cgauaucgug     1080

cagucguuag agaaggcagu ugacauguau aaauacggua agauagcuuu uguggccaug     1140

gagagaauua cuugggauua ugacgggauc ggaucuaaug gcaagaaagu cgaucaugac     1200

aaguuccugg augacgcuga aaaacacuac cucccaaaga cauauaccuu cgauaacggc     1260

acuuuuauca uuagggccgg ggacaaagug uccgaggaaa agaucaagcg gcuuuacugg     1320

gcaucacgcg agguaaaaag ucaguuccau cgaguugugg gaaaugauaa ggcccuggaa     1380

gucgguaacg cugacgacgu guugacaaug aaaauuuuua auagccccga ggaguauaag     1440

uucaacacca auauaaacgg cgucuccacg gauaaugggg gacuauacau cgaaccuaga     1500

ggcaccuuuu acacauauga gaggacucca caacagucua uuuucagccu ggaggagcuc     1560

uuucggcacg aguacaccca uuaucugcag gcgcguuacc uuguggacgg ucuguggggg     1620

caaggcccgu ucuaugaaaa gaaccgcuug acaugguuug augagggaac ugcagaguuc     1680

uuugccggcu caaccagaac aagugggguu cuccccagga aguccauccu gggauacuua     1740

gcuaaagaca agguggauca ccgguauagc cugaagaaaa cccuaaauuc ugguuacgac     1800

gauucagacu ggauguucua caacuauggc uuugccguag cacacuaccu cuaugaaaag     1860

gauaugccua cuuucaucaa aaugaauaag gccauucuga acacggacgu caaaaguuac     1920

gaugaaauaa ucaagaaacu uagcgacgau gcuaacaaaa auacagagua ucagaaccau     1980

auucaggagu uggccgacaa guaccagggg gcaggaaucc cacugguguc cgacgauuau     2040

cucaaagacc acggcuacaa gaaagcgucu gaaguuuacu cggagauuag caaggcugcc     2100

ucccugacca auacuucagu gaccgcagaa aagagucaau auuucaacac auuuacccuu     2160

cgagguacuu acacagggga gacgucuaaa ggcgaguuca aggauuggga cgaaaugagc     2220

aaaaagcugg auggaaccuu ggagucccuc gccaaaaauu cauggagcgg cuauaagacu     2280

cugacagcuu acuuuaccaa cuaucgcguc acaucugaca auaaggugca guacgaugua     2340

guguuccaug ggguuuuaac ugacaacgcc gauaucucca auaacaaagc acccauagcu     2400

aaggucaccg gaccuaguac gggugccgug ggcagaaaua ucgaauuuag cgggaaagac     2460

ucuaaggaug aggacggaaa aauugugucc uaugauuggg acuucggcga cggugcgacc     2520

ucaaggggga agaacagugu ccacgccuac aaaaaggcug gcacauacaa uguuacucug     2580

aaggugaccg augacaaagg agcaacagcc acugagagcu uuaccaucga aauuaagaac     2640

gaagauacga caaccccaau cacuaaagag auggagccca augacgauau aaaggaagcu     2700

aacggcccga uuguggaggg gguaacaguc aaaggagacc uaaacggcuc ggaugacgcc     2760

gauaccuucu auuuugacgu gaaggaagau ggugacguua cuaucgagcu cccuuacucc     2820

gggucuagca auuucaccug gcugguguau aaggagggag acgaucagaa ccacauugca     2880

ucaggcaucg acaaaaauaa caguaagguc gguacauuua aauccacgaa gggccggcau     2940

uacguguuca uauauaaaca cgauucugcg agcaauaucu ccuacucacu uaacauuaag     3000

ggguugggaa augaaaagcu gaaagagaag gaaaacaaug acagcaguga uaaagccacc     3060

guuaucccca acuuuaauac uacaaugcag ggcucucucc ugggggacga uucccgcgac     3120

uauuacagcu ucgaggugaa ggaagaggga gagguaaaca uugaauuaga uaaaaaggac     3180

gaguucggcg ucaccuggac acugcaucca gaaucgaaua ucaacgauag aauaacuuac     3240

ggucaagugg acgggaauaa ggugucaaac aaagucaaac uuaggccugg aaaauauuac     3300

uugcucguuu auaaguacuc uggcaguggu aauuaugagc ugcgugugaa caaauga        3357


<210>  414
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  414
augaaguggg ugaccuucau cagccugcuc uuucuuuucu ccucugccua cucaauugcu       60

aacacaaaua gugagaaaua ugacuuugaa uaccugaacg gcuugagcua uacugaguua      120

acgaaucuga uaaagaacau caaauggaau cagauuaacg ggcuauucaa uuacuccacc      180

ggaucucaaa aguuuuucgg ugauaaaaac agaguccagg caaucauuaa ugcccuccag      240

gaaucgggca ggacauauac ugcgaacgac augaagggga ucgagaccuu uacagaaguu      300

cugcgggcug gauucuaccu uggcuauuac aaugaugguc ugucauacuu gaacgaccgc      360

aauuuucagg auaagugcau acccgccaug aucgcaauuc agaaaaaccc uaauuucaag      420

cucgggaccg ccgugcaaga cgagguaauc acuagccugg gaaaacugau uggcaacgcu      480

agugcaaacg ccgagguggu caauaacugu gugccaguuc ucaagcaguu ucgagaaaau      540

uuaaaccagu augcuccgga uuacgugaaa ggcacagccg ucaaugagcu gaucaagggg      600

auagaauuug acuuuuccgg agcggcauau gagaaggaug ugaaaaccau gcccugguac      660

gguaagauug acccuuucau caacgagcuu aaagccuugg gccuguaugg gaauauuacg      720

ucugcuacug aaugggccag cgauguagga aucuacuauc uauccaaguu cggccucuac      780

ucaaccaacc guaaugacau cguucaaagu cuggagaaag caguggauau guacaaguau      840

gguaaaauug cuuuugucgc cauggaaaga auaacauggg acuacgacgg gaucggaagc      900

aacggcaaga agguggauca cgacaaauuc cuugaugacg cggagaagca uuaucugcca      960

aaaacuuaca ccuuugauaa uggcacauuc auuaucaggg ccggggacaa ggugucugaa     1020

gagaaaauaa agcgguugua uugggcaucc cgcgagguca agucacaguu ucacagaguu     1080

gugggaaacg auaaagcucu cgaaguaggu aaugccgacg augugcugac caugaagauu     1140

uucaacagcc ccgaggaaua caaauuuaau acgaacauca acggcgucag uacugacaau     1200

gggggauuau auaucgagcc uaggggcaca uucuacaccu acgaacggac uccacagcag     1260

ucuauuuucu cccuggagga gcuguuccgc caugaauaua cacacuaccu ucaagcucga     1320

uaucuggugg augguuugug ggggcagggc cccuuuuacg agaagaacag acuaaccugg     1380

uucgacgaag gaacggccga guuuuucgca ggcagcacca ggacaucggg gguucugccu     1440

cggaaaucua uccucggaua ucuggccaag gacaaggugg aucaucguua cucccuuaaa     1500

aagacucuca auucagguua ugacgauagu gacuggaugu ucuacaacua cggcuuugcu     1560

gucgcgcacu auuuguacga aaaagauaug ccaaccuuca uuaagaugaa uaaagcaaua     1620

cucaacacag acguaaagag cuaugaugag aucauuaaga aacuguccga cgaugccaau     1680

aagaacacug aguaccagaa ucacauccaa gaauuagcug acaaauauca gggggccgga     1740

aucccgcugg ugucugauga cuaccuaaag gaucauggcu auaaaaaggc aagcgagguu     1800

uacucagaaa uuaguaaagc cgcuucccuc accaacacaa gcgugaccgc cgagaagucu     1860

caguacuuua auacuuucac gcugcgcggu acauauaccg gggagacuuc aaagggcgaa     1920

uuuaaagacu gggacgagau gaguaagaaa cuugauggaa ccuuggaaag ccuggcaaag     1980

aacuccuggu cuggcuacaa aacacucacc gcguauuuca cuaauuacag agucacaucg     2040

gacaacaagg ugcaguauga ugucguguuu cacgggguuc ugacggacaa ugcugauaua     2100

agcaacaaca aggcccccau cgcaaaagug accggaccuu ccacuggugc cguaggcagg     2160

aauauugagu ucucagggaa ggacaguaaa gaugaagacg gaaagaucgu cucuuacgau     2220

ugggacuuug gcgauggugc uacaagccgg gggaaaaacu ccgugcaugc cuauaagaag     2280

gcaggcaccu acaauguuac acuuaaagug acugacgaua agggagcuac cgccacggag     2340

ucauucacca uugagaucaa aaacgaagac acaacuaccc caauaacaaa ggagauggaa     2400

cccaaugacg auaucaaaga ggcgaacggc ccuauugucg aaggggugac uguaaaggga     2460

gaccugaaug gcagcgauga cgccgauacc uuuuacuucg acgugaagga ggauggugac     2520

guuacgaucg aguugccaua uucugggucc aguaacuuua cauggcucgu cuacaaagaa     2580

ggagaugacc aaaaucacau ugcuagcggc aucgauaaga acaauucuaa aguggguacc     2640

uucaagucca cuaaaggccg acacuaugug uucauauaca agcaugacuc agcaaguaac     2700

auuagcuauu cgcugaauau caaaggguua ggaaacgaga agcugaagga aaaagagaau     2760

aacgacuccu cugauaaggc cacagucauu cccaacuuua auaccacuau gcagggcagc     2820

cuacucgggg acgauucacg cgacuacuau aguuucgaag uuaaagagga gggagaagug     2880

aacaucgagc uggauaagaa agacgaauuu ggcgugaccu ggacacuuca cccggagucc     2940

aauauaaacg auagaaucac guacggucag guagacggga auaaggucuc uaacaaggug     3000

aaauugaggc cuggaaagua cuaucugcuc guuuacaaau auagcggcuc cgguaauuac     3060

gagcugcggg ugaacaagug a                                               3081


<210>  415
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  415
augaaguggg ugaccuucau cagccugcuc uuucuuuucu ccucugccua cucaaugaaa       60

aagaacauuc ugaaaauauu gauggacagu uauagcaagg aguccaaaau ccagacaguc      120

agaaggguua cuucuguguc guuacuggcu guauaccuaa cgaugaauac cucaagccuc      180

gugcuggcaa agcccauuga aaacacaaau gauacuagca ucaagaacgu cgagaaacuu      240

cggaaugccc cuaacgaaga aaauuccaag aaaguggaag acucuaagaa cgauaaaguu      300

gagcacguga agaauauuga ggaagcgaag gucgagcaag uggcuccaga aguaaaaagc      360

aaguccaccc ugcgcucagc cagucgacgu agaaggaaac ggaucgcaaa cacaaauagc      420

gagaaguaug acuuugagua cuugaacggc cucucuuaua ccgaacugac uaaucugauc      480

aaaaacauaa aguggaauca gauuaacgga cucuucaacu acuccacagg aucacagaaa      540

uuuuucggug auaagaaucg cguucaggcc aucauuaacg cuuuacaaga gagcggcaga      600

accuauacgg caaaugacau gaaggggauc gaaacuuuua ccgaggugcu gagggccgga      660

uucuaccuug gcuacuauaa cgaugguuug aguuaccuga augaccggaa cuuucaggau      720

aaaugcauac cggcuaugau ugccauccag aagaauccca acuucaaacu agggacagcg      780

guccaggacg aagugauuac uucucucgga aagcugaucg gcaaugcauc cgccaacgcu      840

gaggugguca auaacugugu uccugugcuu aaacaauuuc gcgagaaucu gaaccaguau      900

gccccagauu acguaaaggg caccgcagug aaugaauuga ucaaggggau ugaguucgac      960

uuuagcggag cugccuauga aaaagauguc aagacaaugc ccugguacgg uaaaauagac     1020

ccuuucauca acgagcucaa ggcgcugggc uuauauggga acauuaccuc ggccacggaa     1080

ugggcaucug acgugggaau cuacuaccug uccaaauucg gccucuauuc aacuaaucga     1140

aacgauauag uucagagucu ugagaaggcu guggacaugu acaaguaugg uaaaauugcc     1200

uuugucgcua uggagagaau cacaugggau uacgacggga ucggaagcaa uggcaagaaa     1260

guggaucaug acaaguuccu ggaugacgcc gaaaaacacu auuugccaaa gaccuacacu     1320

uuugauaacg gcacauucau uaucagggca ggggacaagg uauccgagga gaaaauuaag     1380

cggcuauauu gggccucucg ugagguuaaa agccaguuuc aucgcguggu cggaaaugau     1440

aaggcucugg aaguggguaa cgcggacgac guccucacca ugaaaauauu caauucaccc     1500

gaggaguaca aguuuaacac gaauaucaac ggcgugagua ccgauaaugg gggacuguac     1560

auugaaccua gaggcacauu cuauacuuac gagaggaccc cacaacaguc caucuuuagc     1620

cuugaggaac uguuccggca cgaguauaca cauuacuugc aggcacgaua ucucguugac     1680

ggucuguggg ggcaaggccc guuuuacgag aaaaaccgcu uaacuugguu cgaugaagga     1740

accgccgaau uuuucgcugg cucuacaaga accucagggg ugcugcccag gaagaguauc     1800

cuaggauauc ucgccaagga caaaguagau caccgguaca gccugaagaa aacucuuaau     1860

uccgguuacg acgauucuga cuggauguuc uauaacuacg gcuuugcagu cgcccacuau     1920

uuguacgaga aggauaugcc uacguucauu aaaaugaaua aggcuauacu gaacacagac     1980

gugaagucgu augaugaaau cauuaaaaag cucagcgacg augccaacaa aaauaccgag     2040

uaccagaacc auauccagga gcuggcagac aaguaucagg gggcggggau uccacuuguu     2100

uccgacgauu accugaaaga ccacggcuac aagaaggcuu cagaagugua uagugagauc     2160

ucuaaagccg caaguuugac uaauaccucc gucacagccg aaaagucaca auacuuuaac     2220

accuucacuc uccgcgguac auauacgggg gagaccagca aaggcgaauu uaaggauugg     2280

gacgagaugu cuaaaaagcu ggauggaacu uuagaguccc uggcuaagaa uaguuggagc     2340

ggcuacaaaa cacuaaccgc cuauuucaca aacuacagag ugacuucuga caauaaggua     2400

caguaugaug ugguuuuuca ugggguccuc accgacaacg cagauauauc caauaacaaa     2460

gcucccaucg ccaaggugac gggaccuuca accggugcgg ugggcaggaa uauugaguuc     2520

agugggaaag acagcaagga ugaagacgga aaaaucgucu cguacgauug ggacuuuggc     2580

gacggugcca caucccgugg gaagaacucu guucacgcuu acaagaaagc aggcacuuau     2640

aaugugaccc ugaaggugac agaugacaaa ggagccacug cuaccgagag cuucacgauu     2700

gaaaucaaga acgaagauac aaccacucca auaacaaaag agauggagcc caaugacgau     2760

auuaaggaag ccaacggccc gaucguagag ggggucaccg ugaagggaga ccuuaacggc     2820

ucagaugacg cagauacuuu uuacuucgac guuaaagaag auggugacgu gaccauugag     2880

uugccuuaua guggguccuc uaauuuuaca uggcuggucu acaaggaggg agacgaucag     2940

aaccacaucg cgagcggcau agacaaaaau aacuccaagg uggguacguu caaaucaacc     3000

aagggccggc auuauguuuu caucuacaag cacgauagcg ccaguaauau uucuuauucc     3060

cucaacauca aagggcuggg aaaugaaaag uuaaaagaga aggaaaacaa ugacagcucg     3120

gauaaagcua cugugauucc caacuuuaau acaaccaugc agggcucacu gcuuggggac     3180

gauucucgag acuacuacag uuucgaggua aaggaagagg gagaggucaa caucgaauug     3240

gauaagaaag acgaguuugg cgugacaugg acucuccauc cagaauccaa uauaaacgau     3300

agaauuaccu auggucaagu ggacgggaau aaggucagca acaaaguuaa gcugaggccu     3360

ggaaaauacu aucuacuggu guacaaguau ucuggcagcg guaauuacga gcuccgcgua     3420

aacaaguga                                                             3429


<210>  416
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  416
augaacuucc ugaagaucau ucucaauaga ggcaaaacca ugaagaggaa augccuuagc       60

aagcggcuga uguuggccau aacaauggcu acuaucuuua cggugaacuc caccuuaccc      120

auuuacgcag ccgucgacaa aaauaacgcg acagcugccg uucagaauga gucuaagcgc      180

uauacugugu cauaccugaa gacccuaaac uauuacgauc ucguagaccu gcuugugaaa      240

acagaaaucg agaaucugcc ugauuuguuc caauauagua gcgacgcaaa ggaauuuuac      300

gggaacaaaa cccgaauguc cuucauuaug gaugagaucg gacguagagc cccacaguau      360

acugaaauag accacaaggg uaucccgaca cucgucgagg ugguuagggc uggcuuuuac      420

cugggguucc auaauaaaga gcugaacgaa auuaauaagc ggucuuuuaa ggagcgcgug      480

auccccucga uucucgcaau ccagaaaaac ccuaauuuca aguuaggaac cgaaguccag      540

gauaaaauag ugucagccac gggccugcuu gcugguaacg agacugcccc acccgaggua      600

guuaauaacu uuaccccuau uuugcaagac uguaucaaga acauugauag auacgcgcug      660

gacgaucuaa aaagcaaggc acucuucaau gugcuggccg cuccaacaua ugacaucacu      720

gaauaccuua gggccaccaa agagaagccc gaaaacacac cuugguaugg gaagaucgau      780

ggauuuauua augagcugaa aaaguuggca cucuacggca aaauaaacga caauaacagu      840

uggaucauug acaauggcau cuaucacaua gcuccacugg ggaaguuaca uuccaacaau      900

aaaauuggaa ucgaaacccu gacggagguc augaaggugu acccguaucu cucuaugcag      960

caccuucaga gcgccgauca gaucaagcgg cauuacgacu ccaaagaugc ggaggguaac     1020

aagauucccc uggacaaauu caagaaagaa ggcaaggaga aguacugccc uaaaacuuau     1080

acauuugaug acgggaaggu gaucauuaaa gccggagcac gcgucgaaga ggaaaagguu     1140

aaacgauugu acugggcuuc aaaggaggug aauagucaau ucuucagagu auauggcaua     1200

gauaagccac uagaggaagg uaaccccgac gauauccuga ccauggugau uuacaauagc     1260

ccugaggaau auaaacucaa cucuguccug uacggguaug acacuaauaa cggaggcaug     1320

uacaucgagc cagaaggcac auuuuucacc uacgagaggg aggcccagga auccacguau     1380

acccuugagg aacuguuucg gcacgaguac acacacuauu ugcaggggcg uuacgcugug     1440

cccggacagu ggggucgcac uaagcucuau gauaacgaca gacugaccug guacgaggaa     1500

ggcggggccg aguuauucgc aggaucaaca aggacuagcg gcauccugcc gcggaaaagu     1560

auuguuucua auauacauaa caccacacga aauaaccgcu auaagcuauc cgacaccgug     1620

cacagcaaau acggugccuc guuugaguuc uacaauuaug cuuguauguu uauggauuac     1680

auguauaaca aggacauggg gauccucaau aaacugaacg aucuugcgaa gaauaacgac     1740

gucgauggcu acgacaauua uauuagagau uugucuucca acuacgcacu gaaugacaag     1800

uaucaagauc auaugcagga aaggaucgac aacuacgaaa aucucacugu gccuuucgua     1860

gccgaugacu accugguucg gcacgcuuau aaaaacccca acgagauuua cucagagauc     1920

agugaagugg ccaaacuuaa ggaugcaaag agcgagguca aaaaguccca guauuuuucu     1980

acguucacac ugcgcggaag cuacaccggc ggggccucaa agggaaaauu ggaagaccaa     2040

aaggcuauga auaaauuuau agacgauagu cucaagaaac uggacacuua uuccuggagc     2100

gguuacaaga ccuuaacagc cuauuucacc aacuacaagg uggauucuuc aaauagaguc     2160

acuuacgacg ugguuuuuca cggcuaucug ccaaacgagg gggauaguaa aaauagccua     2220

ccuuacggaa agaucaacgg cacauauaaa gguacggaaa aggagaaaau uaaguucucc     2280

ucugaggggu cguucgaccc cgauggcaag aucgugagcu acgaauggga cuuuggagau     2340

ggcaauaaau ccaacgagga aaauccagag cauucauaug acaagguagg gaccuacacu     2400

gucaaacuca aggugacaga ugacaaagga gaaaguucug uuagcaccac aacugcagag     2460

auuaaggauc uguccgagaa caaacuuccc gugaucuaua ugcacguccc uaagucaggu     2520

gcguugaauc agaagguggu auucuacggc aaagggaccu acgacccaga cggaagcaua     2580

gcuggcuauc agugggauuu uggugacggg ucugauuucu ccagugaaca gaacccgagc     2640

cauguguaca cgaagaaagg cgaguauacc guuacacuga gggucaugga cucuuccgga     2700

caaaugucag aaaagacuau gaaaauuaag aucaccgauc ccguguaccc uauuggcaca     2760

gagaaggagc caaauaacag uaaagaaacu gccagcgggc ccaucgugcc uggaauacca     2820

gucucgggca ccaucgagaa uacguccgac caggauuauu uuuacuucga cguuauuaca     2880

cccggugaag ugaagaucga uauuaacaaa cucggguaug gaggcgcaac cuggguggua     2940

uacgacgaga acaauaacgc cgucucuuac gcuacugaug acggucagaa ucugagcggc     3000

aaguuuaaag ccgacaagcc ggggcguuau uacauccacu uauauauguu caacggauca     3060

uacaugccuu aucggauaaa uauugaaggc aguguggggc gauga                     3105


<210>  417
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  417
augaagagaa aaugccugag caagaggcuc augcuugcca ucaccauggc uacaauuuuc       60

acugugaacu ccacgcugcc cauauacgca gccgucgaca aaaauaacgc gaccgcugcc      120

guucagaaug agucuaagcg guauacagug ucauacuuga aaacuuuaaa cuauuacgau      180

cugguagacc uacucgugaa gaccgaaauc gagaaucugc cugaucuuuu ucaauauagu      240

agcgacgcaa aggaguucua cggcaacaaa acacgcaugu ccuuuauuau ggaugaaauc      300

gggcgacgug ccccacagua uaccgaaauu gaccacaagg gaaucccgac ucuggucgag      360

gugguuagag cugguuucua cuugggcuuu cauaauaaag agcucaacga aauaaauaag      420

aggucuuuca aagagcgggu gauccccucg auucuggcaa uccagaagaa cccuaauuuu      480

aagcugggga cagaagucca ggauaaaauu gugucagcca ccggacucuu agcuggcaac      540

gagacggccc cacccgaggu aguuaauaac uucacuccua uccugcaaga cuguauaaag      600

aauauugauc gcuacgcgcu ugacgauuug aaaagcaagg cacuguuuaa cgugcuagcc      660

gcuccaaccu augacaucac agaauaccuc agagccacua aagagaagcc cgaaaacacc      720

ccuugguaug guaaaauuga uggguucauc aaugagcuga agaagcuggc acuguacgga      780

aaaaucaacg acaauaacag uuggauuaua gacaauggca ucuaucacau ugcuccauug      840

ggcaagcucc auuccaacaa uaaaaucggg auagaaacac ugaccgaggu caugaaggug      900

uacccguauu uaucuaugca gcaccuucag agcgccgauc agauuaaaag gcauuacgac      960

uccaaggaug cggagggaaa caagaucccc cucgacaaau uuaagaaaga agguaaggag     1020

aaauacugcc cuaagacgua uacuuucgau gacggcaagg ugaucauuaa agccggggca     1080

cgggucgaag aggaaaaggu uaaacgccuu uacugggcuu caaaggaggu gaauagucaa     1140

uuuuuccgag uauauggaau cgauaaacca cuggaggaag gcaaccccga cgauauuuug     1200

acaaugguga uauacaauag cccugaggaa uauaagcuaa acucuguccu guacgguuau     1260

gacaccaaua acgggggaau guacaucgag ccagaaggca cuuucuuuac auacgagaga     1320

gaggcccagg aauccaccua uacgcucgag gaacuguuca ggcacgagua cacccacuau     1380

cuucagggcc gguacgcugu gcccgggcag uggggacgua caaagcugua ugauaaugac     1440

cgcuugacuu gguacgagga agguggcgcc gagcucuuug cagggucaac cagaacaagc     1500

ggcauucugc cgaggaaaag uaucguuucu aacauccaua acacuacccg gaauaaccga     1560

uauaaguuau ccgacacagu gcacagcaaa uacggagccu cguucgaauu uuacaauuau     1620

gcuuguaugu ucauggauua cauguauaac aaggacaugg guauucugaa uaaacuaaac     1680

gaucucgcga agaauaacga cgucgauggg uacgacaauu auauacgcga ucugucuucc     1740

aacuacgcac uuaaugacaa auaucaagau cauaugcagg agagaaucga caacuacgaa     1800

aauuugaccg ugccuuuugu agccgaugac uaccugguua ggcacgcuua uaagaacccc     1860

aaugagauuu acucagagau cagugaagug gccaagcuca aagaugcaaa gagcgagguc     1920

aaaaaguccc aguauuucuc uacuuuuacg cugcggggca gcuacacagg aggcgccuca     1980

aaagggaaac uugaagacca aaaggcuaug aacaaguuca uugacgauag ucugaagaaa     2040

uuggacaccu auuccuggag cggauacaag acucucaccg ccuauuuuac aaacuacaaa     2100

guggauucuu caaaucgcgu caccuacgac gugguuuucc acgguuaucu gccaaacgag     2160

ggcgauagua agaauagcuu accuuacggg aagaucaacg gaacuuauaa aggcacagaa     2220

aaggagaaaa uaaaguuuuc cucugagggu ucguucgacc ccgaugggaa aaucgugagc     2280

uacgaauggg acuucggcga uggaaauaag uccaacgagg aaaauccaga gcauucauau     2340

gacaagguag gcacguacac cgucaaacug aaggugacug augacaaagg ggaaaguucu     2400

guuagcacaa ccacagcaga gauuaaggau cuauccgaga acaaacuccc cgugaucuau     2460

augcacgucc cuaagucagg agcgcugaau cagaaagugg uauuuuacgg uaagggcacu     2520

uacgacccag acgggagcau ugcuggauau cagugggauu ucggcgacgg uucugauuuu     2580

uccagugaac agaacccgag ccauguguac accaagaaag gggaguauac gguuacccuu     2640

agagucaugg acucuuccgg ccaaauguca gaaaagacaa ugaaaaucaa gauaacugau     2700

cccguguacc cuauuggaac cgagaaagag ccaaauaaca guaaggaaac agccagcggc     2760

cccaucgugc cugggauucc agucucggga acuaucgaga auaccuccga ccaggauuau     2820

uucuacuuug acguuauaac gcccggcgaa gugaagaucg auauuaacaa auuggguuau     2880

gggggagcaa cauggguggu auacgacgag aauaacaacg ccgucucuua cgcuaccgau     2940

gacggccaga aucugagcgg uaaguucaaa gccgacaagc cgggcaggua uuacauccac     3000

cucuauaugu uuaacggguc auacaugccu uaucguauua auaucgaagg aagugugggc     3060

cgguga                                                                3066


<210>  418
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  418
augaaguggg ugaccuucau cagccugcuc uuucuuuucu ccucugccua cucaguccag       60

aacgagagua aaagauauac aguuagcuac cugaagacuu ugaauuauua cgacuuagug      120

gaucugcuag uaaaaacgga aauugagaac cuccccgacc uguuucaaua uuccucugau      180

gcuaaggagu ucuacggcaa uaaaaccagg augucguuua uaauggacga aaucggccgg      240

cgcgcaccuc aguauacaga aauugaucac aagggaaucc caacucuugu ggaggucgug      300

cgagccgguu ucuaccuggg cuuucauaac aaggaguuga augaaauuaa caaacguuca      360

uucaaggaga gaguuauccc gagcauacuc gcgauccaga aaaaucccaa cuuuaagcug      420

gggaccgaag ugcaggacaa aauugucagu gcuacaggac ugcucgccgg caaugagacc      480

gcaccuccag aggugguaaa caauuucacu cccaucuuac aagauugcau uaagaacauc      540

gacagguacg cccuggauga ccuuaagucc aaggcuuugu uuaauguucu ggcagccccu      600

acauaugaua uaaccgaaua ccuacgggcu acgaaggaga aaccagaaaa cacucccugg      660

uaugguaaga uugacggguu caucaaugag cucaaaaagc uggcccuuua cggaaaaauu      720

aacgauaaca auucuuggau caucgacaac ggcauuuauc acauagcgcc ucugggcaag      780

uugcauagca auaacaagau cgggauugaa acccucacag aggugaugaa agucuaccca      840

uaucugucca ugcagcacuu acagucagca gaccagauca agcgccauua cgauaguaaa      900

gacgccgagg gaaauaagau accgcuggau aaauuuaaga aggaagguaa agagaaguac      960

ugucccaaaa cuuauaccuu cgacgauggc aaggugauua ucaaagcugg ggccagagug     1020

gaagaggaaa aggucaagag gcucuacugg gcaagcaaag agguuaacuc ucaauucuuu     1080

cggguguaug gaaucgacaa gccucuugag gaaggcaauc cagaugacau ucugacaaug     1140

guaaucuaca acucccccga ggaauauaaa cuaaauucag uguuguacgg uuaugauacc     1200

aacaaugggg gaauguacau ugagccugaa ggcacguucu uuacuuacga gcgcgaggcu     1260

caggaaagca cauauacccu ggaggaacuc uuccgacacg aguacacuca cuaucugcag     1320

ggcagauacg ccgucccagg gcagugggga aggacaaaac uuuaugacaa cgaucggcug     1380

accugguacg aggaaggugg cgcggaguug uuugccggga guacgcguac cucuggaaua     1440

cucccccgca aauccaucgu gagcaauauu cauaacacaa cuagaaauaa cagguauaag     1500

cugucggaca ccguucacuc uaaguacggc gcauccuucg aauuuuacaa cuaugcuugc     1560

auguucaugg acuacaugua uaauaaagau auggguaucu uaaacaagcu gaaugaccua     1620

gccaaaaaca augaugugga cggguacgau aacuauaucc gggaccucuc aaguaauuac     1680

gcucugaacg auaaguauca agaccauaug caggagcgaa uugauaauua cgaaaaccuu     1740

acagucccgu uuguggccga cgauuacuug guacgccacg cauauaaaaa uccuaacgag     1800

auauacagcg agaucuccga aguugccaag cugaaagacg cuaagucuga ggugaagaaa     1860

agccaguauu ucucaacuuu uacccucaga ggcaguuaca caggaggcgc guccaagggg     1920

aaacuggaag aucaaaaggc aaugaauaaa uucauugacg acagccuuaa gaagcuggau     1980

accuauucuu ggucaggaua caaaacuuug acggccuauu uuacaaacua caaggucgac     2040

aguagcaaua gggugaccua cgaugucgug uuccacgguu aucuccccaa cgagggcgac     2100

uccaaaaacu cucugccaua cgggaagauc aauggaacuu auaaaggcac cgaaaaggag     2160

aagauuaaau ucucgagcga ggguuccuuu gauccugacg ggaagaucgu uucauacgaa     2220

ugggauuucg gcgacggaaa caaaaguaau gaggaaaacc ccgagcauuc uuaugauaag     2280

gugggcacau acaccguaaa auuaaagguc acugacgaua agggggaaag cuccguguca     2340

acaacgaccg cugagauaaa agaccugagc gagaauaagc uaccaguuau cuauaugcac     2400

gugcccaaau cuggagcccu caaccagaag gucguguuuu acgguaaagg cacuuacgau     2460

ccugacgggu ccauugcagg auaucagugg gacuucggcg augguaguga cuuuagcucu     2520

gaacagaauc caucccaugu auacacaaag aaaggggagu auaccgugac acugcggguu     2580

auggauucaa guggccaaau gagcgaaaag acuaugaaga ucaaaauuac cgacccgguc     2640

uaccccaucg gaacggagaa ggagccuaac aauucgaaag aaaccgccuc cggcccaaua     2700

gugcccggga uuccuguguc uggaacaauc gagaacacua gcgaucagga cuauuucuac     2760

uuugauguca uuaccccagg cgaaguuaag aucgacauaa auaaacuugg uuauggggga     2820

gcuacauggg ugguguacga ugagaacaau aacgccguau cauacgcaac ugacgauggc     2880

cagaauuuga gugguaaguu caaggcggac aaacccggcc gcuauuacau ccaccuguau     2940

auguuuaacg gguccuacau gccguauaga auuaacaucg aaggaucugu cgggagguga     3000


<210>  419
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  419
augaaguggg ugaccuucau cagccugcuc uuucuuuucu ccucugccua cucaaugaaa       60

agaaagugcc ugaguaaaag guugauguua gcuauuacaa uggcaacuau auuuacgguc      120

aacagcaccc ugcccaucua ugccgcgguu gacaagaaua acgcuacagc cgcacggcgc      180

cgacguaaaa gagugcagaa ugaguccaag agguacacug uaucuuaucu aaagacccuc      240

aacuacuaug aucuggugga ccuucugguc aaaacagaaa uugagaauuu gccugaucuc      300

uuccaauacu cgucagacgc caaggaauuu uauggcaaca aaacccggau gagcuucauc      360

auggaugaga uugggcgcag agcuccacag uacacugaaa ucgaccacaa gggaauaccg      420

acacuggugg agguugugag ggcagguuuu uaccugggcu uccauaauaa agagcucaac      480

gaaaucaaua agcggaguuu uaaggagcgc gucauucccu ccaucuuagc cauucagaaa      540

aacccuaauu ucaagcuggg gaccgaagug caggauaaaa ucguaucugc uacgggacuu      600

uuggccggca acgagacugc gccacccgag guugugaaua acuuuacccc uauacugcaa      660

gacuguauua agaauaucga ucgauaugca cuagacgauc ucaaaagcaa ggcccuguuc      720

aacguccuug cugccccaac auacgacauu acugaauauc ugagagcaac caaagagaag      780

cccgaaaaca caccuuggua cgguaagauc gauggguuua ucaaugaguu gaaaaagcuc      840

gcucuguaug gaaaaauuaa cgacaauaac uccuggauaa ucgacaaugg cauuuaccac      900

aucgccccau uaggcaagcu gcauucaaac aauaaaauag ggauugaaac ccucacggag      960

gugaugaagg uguauccgua ccuuaguaug cagcaucugc agagcgcgga ucagaucaag     1020

aggcacuacg acucuaaaga ugccgaggga aacaagaucc ccuuggacaa auucaagaaa     1080

gaagguaagg agaaguauug cccuaaaacu uacacauucg augacggcaa ggucauuauc     1140

aaagcagggg cucggguuga agaggaaaag gugaaacguc uauauugggc cuccaaggag     1200

guaaauucac aauuuuuccg cguguacgga auugauaagc cacuggagga aggcaacccc     1260

gacgauauac ucaccauggu caucuauaau agcccugagg aauacaaacu gaacagugug     1320

cuuuaugguu acgacacuaa uaacggggga auguacauug agccagaagg cacauuuuuc     1380

accuaugaga gagaggcuca ggaaucuacg uacacccugg aggaauuguu uaggcacgag     1440

uauacacacu accuccaggg ccgguaugcc guucccgggc aguggggacg aacuaagcug     1500

uacgauaaug accgcuuaac cugguaugag gaagguggcg cagagcuguu cgccgggucc     1560

acaagaacua gcggaauccu accgaggaaa ucgaucgugu cuaacauuca uaacaccaca     1620

cggaauaacc gcuacaagcu cuccgacacc guccacucaa aauacggcgc uaguuuugag     1680

uucuauaauu acgcguguau guuuauggau uauauguaca acaaggacau ggguauacug     1740

aauaaacuua acgauuuggc aaagaauaac gacguggaug gguaugacaa uuacaucaga     1800

gaucugagcu ccaacuaugc ccucaaugac aaguaccaag aucauaugca ggaaaggauu     1860

gacaacuacg aaaaucugac uguaccuuuc guugcugaug acuaucuugu gcgucacgcc     1920

uacaaaaacc ccaaugagau cuauucugag auuagcgaag ucgcaaagcu gaaagaugcc     1980

aagucagagg ugaaaaagag ucaguacuuu uccacguuca cauugcgggg cagcuauacc     2040

ggaggcgcuu cuaaggggaa acucgaagac caaaaggcca ugaacaaauu uaucgacgau     2100

ucacugaaga aauuagacac uuacaguugg agcggauaua agacccugac agcauacuuc     2160

accaacuaca aggucgauuc cucuaaucga gugacuuaug acguuguguu ccacgguuac     2220

cuaccaaacg agggcgauuc gaaaaauagc cucccuuaug ggaagauaaa cggaacauac     2280

aaaggcacgg aaaaggagaa aaucaaguuu uccucagagg guaguuucga ccccgauggg     2340

aagauuguau cuuaugaaug ggacuuuggc gauggaaaua aaagcaacga ggaaaaucca     2400

gagcauuccu acgacaaggu cggcaccuau acugugaaac ugaagguuac agaugacaaa     2460

ggggaaucaa gcgugucuac cacaacugcg gagaucaagg aucuuuccga gaacaaauug     2520

cccgucauuu acaugcacgu gccuaagagu ggagcucuga aucagaaggu aguguucuac     2580

gguaaaggca ccuaugaccc agacgggagc aucgccggau accaguggga uuuuggcgac     2640

gguucugauu ucuccucaga acagaacccg agucauguuu auacgaagaa aggggaguac     2700

accgucacac ucagagugau ggacagcucg ggccaaaugu ccgaaaagac uaugaaaaua     2760

aagauuaccg aucccgugua uccuaucgga acagagaagg agccaaauaa cucuaaagaa     2820

acugcaagcg gccccauugu cccugggauc ccaguuucag gaaccauaga gaauacgagu     2880

gaccaggauu acuuuuauuu cgacgugauc acacccggcg aagugaagau ugauaucaac     2940

aaacuggguu acgggggagc caccugggua gucuacgacg agaauaacaa cgcugugucc     3000

uaugccacug augacggcca gaauuuaucu gguaaguuua aagcagacaa gccgggcagg     3060

uacuauauuc accuguacau guucaacggg agcuauaugc cuuaccgcau caauauagaa     3120

ggauccguug gccgguga                                                   3138


<210>  420
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  420
augggcaccu ggauccuguu cgccugccuc cuuggggcug cauuugccau gccccugccu       60

ccacacccgg gacaucccgg uuacauuaac uucagcuaug agguguugac accuuuaaag      120

ugguaccagu ccauaagacc acccuauccu ucuuacggcu augaaccaau gggagggugg      180

cugcaccauc aaaucauucc cguccuauca cagcagcacc cuccaacuca uacgcuccag      240

ccgcaccacc auauccccgu ugugccugcg caacagccag uaauucccca gcagccuaug      300

augccagugc ccggccaaca caguaugacc ccgauccagc aucaccagcc uaaucugccc      360

ccuccagcuc agcaacccua ccagccacag cccguccaac cucagccaca ccagccgaug      420

cagccccaac cuccagugca ucccaugcag ccucuuccac cccagccgcc ucugccaccc      480

auguuuccua ugcagcccuu gccaccuaug cuccccgacc ugacacugga ggccuggcca      540

agcacugaua aaaccaagag ggaagagguu gacuga                                576


<210>  421
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  421
augccccugc cuccacaccc gggccauccc ggguacauca acuucagcua ugaggugcuc       60

accccucuua agugguacca guccauuaga ccacccuauc cuucuuacgg auaugaacca      120

auggguggcu gguga                                                       135


<210>  422
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  422
augccccugc cuccacaccc gggccauccc ggguacauca acuucagcua ugaggugcuc       60

accccucuua agugguacca guccauuaga ccacccccua ugcugccaga cuugacauua      120

gaagccuggc ccucuacuga uaaaacgaag agggaggaag ucgacuga                   168


<210>  423
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  423
auggccguga uggcucccag aacccugguc cuccuucuga gcggcgcauu ggccuuaaca       60

cagacuuggg cgaugccucu gccaccgcac cccgggcauc cuggauacau caacuucucc      120

uaugagguuc uaacgccacu caagugguac caaucuauua ggcccccuua uccaucauac      180

gguuaugaac ccaugggcgg gugguga                                          207


<210>  424
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  424
auggccguga uggcucccag aacccugguc cuccuucuga gcggcgcauu ggccuuaaca       60

cagacuuggg cgaugccucu gccaccgcac cccgggcauc cuggauacau caacuucucc      120

uaugagguuc uaacgccacu caagugguac caaucuauua ggcccccucc aaugcugccc      180

gaccuuaccc uggaggcuug gccuucaaca gauaaaacua agcgggaaga aguggacuga      240


<210>  425
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  425
augggcaccu ggauccuguu cgccugccuc gugggggcug cauuugccau gccccuuccu       60

ccacacccgg gacaucccgg uuacauuaac uucagcuaug agguccugac accuuugaag      120

ugguaccagu ccaugauaag accacccuau ucuucauacg gcuaugaacc uaugggaggg      180

ugguuacacc aucaaaucau uccaguugug agucagcagc acccccugac ucauacgcua      240

cagagccacc accauauccc uguagugcca gcgcaacagc cgaggguccg gcagcaggcu      300

cucaugcccg ugccuggcca acaguccaug accccaacac agcaccauca gcccaaucug      360

ccucuuccag cccaacagcc cuuucagccg caaccuguuc agccccagcc acaccagccu      420

augcaacccc agccacccgu gcagccuaug cagccacugu ugccgcaacc cccucuccca      480

cccauguucc cucugcgccc acugcccccg auucucccug acuuacaccu ggaggcaugg      540

ccagccacug auaaaaccaa gcaggaagag gucgacuga                             579


<210>  426
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  426
augccccugc cuccacaccc gggccauccc ggguacauca acuucagcua ugaggugcuc       60

accccucuua agugguacca guccaugauu agaccacccu auucuucaua cggauaugaa      120

ccuaugggug gcugguga                                                    138


<210>  427
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  427
augccccugc cuccacaccc gggccauccc ggguacauca acuucagcua ugaggugcuc       60

accccucuua agugguacca guccaugauu agaccacccc cuauacugcc agacuugcac      120

uuagaagccu ggcccgcuac agauaaaacu aagcaagagg aagucgacug a               171


<210>  428
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  428
auggccguga uggcucccag aacccugguc cuccuucuga gcggcgcauu ggccuuaaca       60

cagacuuggg cgaugccucu gccaccgcac cccgggcauc cuggauacau caacuucucc      120

uaugagguuc uaacgccacu caagugguac caaucuauga uuaggccccc uuauucaagu      180

uacgguuaug aaccaauggg cgggugguga                                       210


<210>  429
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  429
auggccguga uggcucccag aacccugguc cuccuucuga gcggcgcauu ggccuuaaca       60

cagacuuggg cgaugccucu gccaccgcac cccgggcauc cuggauacau caacuucucc      120

uaugagguuc uaacgccacu caagugguac caaucuauga uuaggccccc uccaauacug      180

cccgaccuuc accuggaggc uuggccugcc accgauaaaa caaagcagga agaaguggac      240

uga                                                                    243


<210>  430
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  430
augggcaccu ggauccuguu cgccugccuc cuuggggcug cauuuagcau gccccugccu       60

ccacacccgg gacaucccgg uuacauuaac uucuccuaug agguguugac accuuuaaag      120

ugguaccaga auaugauaag acacccauau acuucuuacg gcuaugaacc caugggaggg      180

uggcugcauc accaaaucau uccugucguu ucacagcaga cgccacagag ucaugcccua      240

caaccccacc accauauccc uauggugcca gcgcagcagc cgggcauucc ccagcaaccu      300

augaugccac uccccgguca gcacagcaug accccuacac agcaucacca gccaaaccug      360

ccccuuccgg cucaacagcc uuuucagccc caaccaguac agccucagcc ccaccagcca      420

cugcaacccc aguccccuau gcauccaauc cagccguugc ucccccagcc uccacugccc      480

ccuauguucu cuaugcaauc gcugcuccca gacuuacccc uggaggccug gccggcaacu      540

gauaaaacca agagggaaga gguggacuga                                       570


<210>  431
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  431
augccccugc cuccacaccc gggccauccc ggguacauca acuucagcua ugaggugcuc       60

accccucuua agugguacca gaauaugauu agacacccau auacauccua cggauaugaa      120

cccaugggug gcugguga                                                    138


<210>  432
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  432
augccccugc cuccacaccc gggccauccc ggguacauca acuucagcua ugaggugcuc       60

accccucuua agugguacca gaauaugauu agacacccau cccuguugcc cgacuuaccu      120

cuggaagccu ggccagcuac agauaaaacu aagagggagg aagucgacug a               171


<210>  433
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  433
auggccguga uggcucccag aacccugguc cuccuucuga gcggcgcauu ggccuuaaca       60

cagacuuggg cgaugccucu gccaccgcac cccgggcauc cuggauacau caacuucucc      120

uaugagguuc uaacgccacu caagugguac caaaauauga uuaggcaccc cuauaccucu      180

uacgguuaug aaccuauggg cgggugguga                                       210


<210>  434
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  434
auggccguga uggcucccag aacccugguc cuccuucuga gcggcgcauu ggccuuaaca       60

cagacuuggg cgaugccucu gccaccgcac cccgggcauc cuggauacau caacuucucc      120

uaugagguuc uaacgccacu caagugguac caaaauauga uuaggcaccc cucucugcuu      180

ccugaccugc cauuggaggc uuggcccgcc accgauaaaa caaagcggga agaaguggac      240

uga                                                                    243


<210>  435
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  435
augggcaccu ggauccuguu cgccugccuc cuuggggcug cauuuagcau gccccugccu       60

ccacacccgg gacaucccgg uuacauuaac uucuccuaua uaagacaccc uuacacaucu      120

uauggcuacg agccaauggg agggugguug caucaccaga ucauucccgu ggucucacaa      180

cagacuccuc agagucaugc cuuacagcca caccaccaua uccccauggu uccugcgcaa      240

cagccaggca uuccgcagca gcccaugaug ccucugccag gucaacacag caugacgccc      300

acccagcauc accagccuaa ucuaccacuc cccgcucagc aaccguuuca gccucagccc      360

gugcaaccac agccucacca gccccugcag ccacaauccc ccaugcaucc uauccagcca      420

cuucugccgc agcccccuuu gccacccaug uucucuaugc agucgcuccu gccugaccug      480

ccacucgaag ccuggcccgc aacagauaag acuaaaaggg aggaaguaga cuga            534


<210>  436
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  436
augggcaccu ggaucuucuu ugccugccug cucggggcua gccuugcaau gccccugccu       60

ccacacccgg gacaucccgg uuacauuaac uucuccuaug agguguugac accuuuaaag      120

ugguaccaga auaugauaag acacccauau acuucuuacg gcuaugaacc caugggaggg      180

uggcugcauc accaaaucau uccugucguu ucacagcaga cgccacagag ucaugcccua      240

caaccccacc accauauccc uauggugcca gcgcagcagc cgggcauucc ccagcaaccu      300

augaugccac uccccgguca gcacagcaug accccuacac agcaucacca gccaaaccug      360

ccccuuccgg cucaacagcc uuuucagccc caaccaguac agccucagcc ccaccagcca      420

cugcaacccc aguccccuau gcauccaauc cagccguugc ucccccagcc uccacugccc      480

ccuauguucu cuaugcaauc gcugcuccca gacuuacccc uggaggccug gccggcaacu      540

gauaaaacca agagggaaga gguggacuga                                       570


<210>  437
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  437
augggcaccu ggauccuguu cgccugccuc cuuggggcug cauuuagcau gccccugccu       60

ccacacccgg gacaucccgg uuacauuaac uucuccuaug agguguugac accuuuaaag      120

ugguaccaga auaugauaag acacccaucu cugcuacccg accucccucu ggaagccugg      180

ccagcgacug auaaaacgaa gagggaggaa gucgacuga                             219


<210>  438
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  438
augggcaccu ggauccuguu cgccugccuc cuuggggcug cauuuagcau gccccugccu       60

ccacacccgg gacaucccgg uuacauuaac uucuccuaug aggacuugua cuuagaagcc      120

auaagaaucg auaggacagc guuugugcug acuccucuaa agugguauca gaauaugauu      180

cggcacccau acacgucuua uggcuacgag cccaugggag gguggcucca ucaccaaauc      240

auuccugucg uuucacagca gaccccacag agucaugcuc ugcaacccca ccaccauauc      300

ccuauggugc cagcccagca gccgggcaua ccccagcaac cuaugaugcc acuucccggu      360

cagcacagca ugacaccuac ucagcaucac cagccaaacc ugcccuugcc ggcacaacag      420

ccuuuccagc cccaaccagu acagccucag ccccaccagc cacuccaacc ccaguccccu      480

augcauccaa uccagccgcu gcugccccag ccuccauuac ccccuauguu uucuaugcaa      540

ucgcuccugc cagaccuucc cuuggaagcc uggccggcua ccgauaaaac aaagcgcgag      600

gaaguggacu ga                                                          612


<210>  439
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  439
augggcaccu ggauccuguu cgccugccuc cuuggggcug cauuuagcau gccccugccu       60

ccacacccgg gacaucccgg uuacauuaac uucuccuaug agguguugac accuuuaaag      120

ugguaccaga auaugauaag acacccaacu ccccaaucuc augcccugca gccucaccau      180

cacaucccaa ugguccccgc gcagcagccu ggcauuccac aacagccgau gaugccccua      240

ccugggcagc acucaaugac gccaacccag caucaccaac ccaaccuccc ucugccagcu      300

cagcagcccu uucagccgca accuguucag ccccagccac aucaaccucu ucagccccag      360

aguccaaugc accccaucca gccucuguug ccacaaccgc cccucccucc aauguucagc      420

augcaguccc ugcugcccga ccucccuuua gaagccuggc cagcaacaga uaaaacuaag      480

agggaggaag uggacuga                                                    498


<210>  440
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  440
augccccugc cuccacaccc gggccauccc ggguacauca acuucagcua ugaggugcuc       60

accccucuua agugguacca gaauaugauu agacacccau auacauccua cggauaugaa      120

cccaugggug gcuggcugca ucaccaaaua aucccugucg uuucucagca gacuccacag      180

ucacaugccu ugcaacccca ccaccauauu ccuauggugc cagcucagca gccggggauc      240

ccccagcaac cuaugaugcc auuacccgga cagcacagua ugacgccuac ccagcaucac      300

cagccaaacc ugccccuacc ggcacaacag ccuuuucagc cccaaccagu acagccucag      360

ccccaccagc cacuccaacc ccagagcccu augcauccaa uucagccgcu gcuuccccag      420

ccuccacugc ccccuauguu cuccaugcaa ucuuugcucc cagaccugcc ccuggaggcc      480

uggccggcga cagauaaaac uaagagggaa gagguggacu ga                         522


<210>  441
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  441
augcccggcg uggccagacu gccucuccuu cugggguugu uacugcuacc aaggccggga       60

cggccccucg accuggcuga uuacaccuau gaccuugcag aggaagauga cagcgagccu      120

cugaacuaca aggauccaug caaagccgcg gcuuucuugg gugacaucgc ccucgaugaa      180

gaggaccugc gcgcauuuca gguccaacag gccguugauc ugcgacguca cacagcuaga      240

aaguccucua uuaaagcagc cgugcccggc aauacuucaa cgccuaguug ucagagcacc      300

aacgggcagc cacaaagggg agcuugcggc cgguggcgcg guagauccag gucucggcgc      360

gccgcgacau cgcgacccga aagaguaugg ccugacgggg ugauaccauu cgucaucgga      420

ggcaauuuua cuggcucaca gagggcagug uuccggcagg ccaugcguca uugggagaag      480

cacaccugug uuacauuucu cgagcgcacc gaugaagaca gcuauauugu guucacuuac      540

agaccgugcg gguguugcag uuaugucgga aggcggggug gcgggcccca ggcuaucucc      600

auuggaaaga acugugauaa guuuggcauc gugguacaug aguuagguca cguugugggg      660

uucuggcaug aacacacacg accugaccgc gacagacacg ucucuauagu gagggagaau      720

auccaaccag gacaggagua caacuuucug aagauggaac cccaggaggu ggaaagccuu      780

ggcgagaccu augauuucga cuccauuaug cauuacgccc ggaauacguu uucacgcggc      840

aucuucuugg auacuauugu cccuaaauac gaaguuaacg gggugaagcc acccaucgga      900

cagagaacca ggcugaguaa aggugacaua gcacaagcuc guaagcuaua uaaaugcccg      960

gccuguggcg agacacucca ggauagcacu gggaauuuuu cuuccccuga guaccccaac     1020

ggauauucag cgcacaugca uugcguaugg cggauuagcg ugaccccagg cgaaaagauc     1080

auucugaauu ucacaagucu ugaccuguac cgaucuagau uguguuggua ugauuacguc     1140

gaggugaggg acgguuucug gcgcaaggcc ccucuccggg ggagauuuug cggcuccaaa     1200

cugcccgaac caaucguuag caccgauucg agguuauggg uggaguuccg aucuuccuca     1260

aacugggucg gaaagggcuu uuucgcagug uaugaagcua ucugcggggg agacguuaaa     1320

aaggauuacg gucacauuca gagucccaau uacccugacg acuaucgccc aagcaaagua     1380

uguauauggc ggauccaagu guccgagggc uuucacgucg ggcugacguu ccagucuuuu     1440

gagauugaac gucaugauag cugcgccuac gacuaucucg aggugagaga uggacacuca     1500

gaaaguucca cucuuaucgg cagguacugu gguuaugaga agccggacga uauaaaaagc     1560

acaucuucac gccugugguu gaaguucguc agugacggga gcauuaacaa ggcuggcuuu     1620

gccgugaauu ucuuuaaaga aguugaugag ugcucccggc ccaacagagg aggcugugag     1680

cagaggugcc uaaacacccu ggggucuuac aaguguucgu gcgacccugg auaugaacuc     1740

gcaccagaua aacgacgcug ugaggccgcu ugcgguggcu uccugacuaa acuuaauggg     1800

agcaucacau cccccggaug gccuaaagaa uacccaccca acaagaauug uaucuggcag     1860

cugguggcgc cgacccaaua ccggauuuca uugcaguuug acuucuucga gacggagggc     1920

aacgauguau gcaaguauga cuuugucgaa gugagaagug gucucaccgc agauucuaaa     1980

cugcauggga aguucugcgg cagcgagaaa ccugaaguua ucacauccca guacaauaac     2040

augagggugg aguuuaaguc agacaauacu gucagcaaaa agggauucaa ggcccacuuu     2100

uucucugaca aagaugaaug uuccaaggac aacggcgggu gccagcaaga uugugugaau     2160

accuuuggaa guuaugagug ccagugucgu agcggcuucg uauuacauga caacaaacac     2220

gauugcaagg aggcugguug ugaccacaaa gugacaucua cuuccgggac cauuacauca     2280

ccaaauuggc ccgauaagua cccuaguaag aaagaaugca ccugggccau aagcucgacu     2340

cccggacauc gcguuaagcu gacguuuaug gagauggaca ucgaauccca gccagagugu     2400

gcauaugauc accuagaagu cuucgacggc cgggaugcca aagcuccugu gcucgguaga     2460

uuuugcggcu cuaagaaacc cgagccagug cuggccacag ggagcaggau guuccuucga     2520

uuuuacucag acaacagugu ccagcggaag ggauuccaag caucccaugc gaccgagugu     2580

ggcgggcagg uucgcgcuga ugugaaaacu aaggacuugu auucucacgc ccaguucgga     2640

gacaauaacu acccgggcgg uguggauugc gaauggguaa uugucgcaga ggaaggguac     2700

ggaguggagc ugguuuuuca gaccuucgaa guggaggagg aaacagacug cggcuaugau     2760

uacauggagc ucuuugacgg uuaugauagc accgccccua gacugggcag guacuguggg     2820

uccggacccc cagaagaggu cuauucagcu ggcgacagcg ugcuuguuaa guuccacagu     2880

gaugacacua ucacgaaaaa gggguuucau cugcgguaca caucuaccaa auuccaagau     2940

acuuugcacu cccgaaagug a                                               2961


<210>  442
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  442
augguggccg gcaccagaug ccugcucgcu uugcuguugc cccaggucuu acugggaggg       60

gcagccgguc uaguuccuga gcucggcagg cggaaguucg cggcugccag cuccgggcgc      120

ccaucuucac aaccgaguga cgaagugcug agcgaguuug aacuucgacu guuguccaug      180

uucggacuca aacagcgucc cacaccuucu agagaugcag uagugccacc cuacaugcug      240

gaccuguaua ggcggcacuc gggccagccu gguucaccag cccccgauca ucgccucgag      300

agagcugcaa gcagggccaa cacuguccgg aguuuucacc augaagaguc cuuagaggaa      360

cugccugaga cgucugggaa gaccacacgc cgauucuuuu ucaaucuuag cuccauccca      420

acugaagagu uuauuaccuc agcugagcuu cagguguuca gagaacaaau gcaggacgcc      480

cugggaaaca auaguagcuu ucaccauagg auaaacaucu acgagauuau caaaccggcg      540

acagcaaauu cuaaguuccc cguuacccgg cuacucgaua cucgucuggu gaaccagaau      600

gccucccgcu gggaaucauu ugacgucacc ccugcuguga ugagauggac agcccagggc      660

cacgcaaacc acggcuucgu aguugaggug gcucaucuug aagagaaaca aggggucagc      720

aagaggcacg ugcggauuag ucgaucucug caucaggaug agcacuccug gagccagauc      780

cgcccauugc ucgugacguu uggacacgac gguaagggcc auccccugca caaaagagaa      840

aagaggcagg ccaaacauaa gcaacggaaa cgcuuaaagu cgucuuguaa gagacacccu      900

cuguaugucg auuucuccga cguugggugg aaugauugga uaguggcgcc acccggauac      960

caugccuucu auugccacgg cgaguguccg uuuccucucg cagaccaccu uaacucaacu     1020

aaucaugcua ucguacagac ccuggugaac agugucaaua gcaaaauucc caaggccugc     1080

ugugugccaa cagaauuguc cgcuaucucu augcuauacc uggaugagaa cgaaaaaguu     1140

gugcucaaga auuaucagga cauggucgug gaggguugcg gguguaggug a              1191


<210>  443
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  443
augauccccg gcaacagaau gcugauggug guccuccuuu gccagguucu guuaggggga       60

gccagccacg cuuccuugau uccugagacc gguaagaaaa agguggcaga aauacaaggc      120

caugccgggg gaaggcgguc uggccaguca cacgagcugc uacgcgacuu cgaagcgaca      180

cuccugcaga uguuuggucu ucgacguaga ccacagccga guaaaagcgc uguaaucccc      240

gauuacauga gggaccugua ucgguugcaa uccggggagg aagaggagga acagauucau      300

ucuacuggac ucgaguaccc ugaacgccca gccucgagag caaauacggu gaggucauuc      360

caccaugagg agcaccugga aaacaucccc ggcaccagcg agaauagugc cuuucgguuc      420

cuguuuaacc ucuccucuau uccugaaaau gaggucauca gcuccgcuga auuacgccug      480

uuccgagaac agguggauca gggcccagac ugggagagag gguuucacag gauaaacauc      540

uaugagguua ugaagccccc ugcagaggug gucccaggac aucuuauuac acgguugcug      600

gauacucguc uagugcacca uaauguaacc cgcugggaaa cauucgacgu uucaccggcc      660

gugcucagau ggaccaggga gaaacaaccc aacuacgguc uggcuaucga agucacucac      720

cuucaccaga cacggaccca ucagggccag cacgugcgaa uuagucgcag ccugccucaa      780

gggucuggaa auugggccca guugagacca cuccugguga cguuuggcca ugaugguagg      840

gggcacgcgu uaacucggcg cagaagggca aagcguuccc ccaagcauca cucacagcgg      900

gcccgaaaga aaaacaaaaa uuguagaagg cacagccugu augucgacuu cagugauguu      960

ggauggaacg acuggaucgu ggcuccucca ggcuaccaag ccuuuuauug ccauggcgau     1020

ugucccuucc cgcucgcaga ccaccuuaau ucuaccaacc augcuauagu acagacacug     1080

gucaauuccg ugaacagcuc gauuccuaag gccugcugug ugcccacuga guugucugcg     1140

aucuccaugc uauaccugga ugaguacgac aaaguugugc ucaagaacua ucaggaaaug     1200

gucguggagg ggugcggaug ucgcuga                                         1227


<210>  444
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  444
augcccggcc uagggagaag ggcccagugg cucugcuggu gguggggacu ucuguguagc       60

ugcugugguc cuccaccguu gcggcccccu uuaccagcug cagccgcggc ugccgcaggc      120

gggcaacugc uaggagacgg cgguuccccc gggcgcaccg agcagccucc acccucuccu      180

cagucaagua gcggauuccu cuaccgacgu cugaagacac aggagaaaag agaaaugcaa      240

aaggaaaucc uuuccgugcu gggcuugcca cacaggccgc ggccccucca uggccugcag      300

cagccucagc cacccgcccu gcgccaacag gaggaacagc agcaacagca gcaacucccu      360

agaggggagc cacccccggg aagguuaaaa ucugcuccuc uguuuaugcu ugauuuguau      420

aacgcacugu cggccgacaa ugaugaggac ggugcuucag aaggcgagcg gcagcagagc      480

uggccccacg aagccgcgag uuccucucag cgccgacaac caccucccgg ggcagcccau      540

ccacuaaaca gaaagagccu ccuggcuccc ggauccggcu cagguggggc caguccucuu      600

acuagcgcac aggauucugc uuuccugaau gacgccgaua uggucauguc cuuuguuaac      660

uugguggagu acgacaaaga guucucacca aggcagcggc accauaagga auuuaaguuc      720

aaucucagcc agauuccgga gggagaagua gugacggcgg ccgaguuucg uauauauaaa      780

gauugcguca ugggcaguuu caagaaccaa accuuucuga ucucuauuua ccagguguua      840

caggaacacc agcaccgcga cuccgaucug uuccuccuug acacaagagu ugugugggca      900

agcgaggagg gcuggcugga auuugauauc acugcuaccu cgaauuugug ggucgugaca      960

ccccaacaua acauggggcu acagcugucu guaguuacca gggacggagu gcacguccau     1020

ccucgggccg cuggucucgu gggccgagac gggccauaug auaaacagcc cuucauggug     1080

gccuuuuuca aggucuccga gguucacgug cgcacuacaa gaucagcaag uagcaggcgg     1140

cgccagcaau ccagaaauag gucuacccag agccaggacg uagcccgugu gucaagugcu     1200

uccgauuaca acagcucuga acugaaaacg gcgugucgga agcacgagcu uuaugucuca     1260

uuccaagacc ugggauggca ggauuggauu aucgcaccua agggcuacgc cgcuaauuac     1320

ugcgacggug aauguaguuu uccauugaac gcccauauga augcaacuaa ccacgccaua     1380

gugcagaccc ucguucaucu gaugaauccc gaguaugugc cgaaaccuug cugugcucca     1440

acaaaguuaa acgccaucag cguccuguac uucgaugaca acuccaaugu gauucugaaa     1500

aaguaucgaa acaugguagu uagagcaugc gggugucacu ga                        1542


<210>  445
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  445
augcacguga gaagccugag ggccgcugca ccccauuccu ucgucgcccu cugggcgccu       60

cuuuuucugu ugcggucugc uuuagccgac uucucacugg auaacgaggu ucacaguagc      120

uuuauccauc gccgacuacg uucccaggaa agaagggaga ugcaacggga aauucucucu      180

auacugggcc uuccacaccg cccgagaccc caucugcagg ggaagcacaa uucggcaccu      240

auguucaugu uggaccucua caacgccaug gcuguggagg aaggaggugg cccaggggga      300

cagggcuuuu cauaucccua caaagcagua uucagcaccc aggguccucc acuggccagu      360

cugcaagauu cccacuuucu cacagacgcu gauaugguga ugucuuucgu caauuuagug      420

gagcaugaca aggaguuuuu ccaccccagg uaucaucacc gggaauuucg cuucgaucug      480

agcaaaaucc cugaggggga agccguuacu gcggcagagu uucgaauuua caaggacuau      540

aucagagaga gguucgauaa cgaaacguuc cggauuuccg uguaccaggu ccuucaggag      600

cacuugggac gugaaucaga ccuguuucua cucgauaguc gcacccugug ggccagcgag      660

gaaggcuggc uuguguucga caucacagcu acuucuaauc auuggguagu uaacccaaga      720

cacaaucugg gcuugcagcu cuccguggag acccuggaug ggcaaucaau aaacccgaaa      780

uuagccggac ugaucgguag gcauggcccc cagaauaagc agccuuuuau ggucgcauuc      840

uuuaaggcua cagaggugca cuuccggagc auucgaagua ccgggucuaa acagcgcucc      900

caaaacagaa gcaagacucc caaaaaucag gaagcccuca ggauggcgaa cguggccgaa      960

aauucgucuu ccgaccagcg gcaagcaugc aagaaacaug agcuuuaugu cucauuucgc     1020

gaccugggau ggcaggauug gaucauugcu ccagagggcu acgccgcuua cuauugugaa     1080

ggugagugcg ccuucccuuu gaacaguuac augaaugcaa caaaccacgc caucguucag     1140

acccuagugc acuuuauaaa cccagagacg guacccaagc cguguugcgc uccuacucag     1200

cugaaugcga uuagcgugcu cuauuucgac gauuccucua acgucauccu gaagaaauac     1260

agaaauaugg ugguuagggc augugggugc cauuga                               1296


<210>  446
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  446
augaaggcca gcgcugcacu gcucugccuu cuguugaccg ccgcggcuuu cucuccccag       60

ggcuuagccc aaccuguggg gaucaacaca uccacuacgu guugcuacag auuuauuaau      120

aaaaagauac caaaacagag gcuggaguca uaucggcgca ccacaaguag ccacuguccg      180

cgagaagcag ucaucuucaa gacuaaacua gacaaggaga uuugcgccga ucccacccag      240

aaguggguuc aggacuuuau gaaacaucuc gauaagaaaa cacaaacccc uaagcuguga      300


<210>  447
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  447
augcugcuca cccuuaucau ucuguugccc guggucagca aguucuccuu uguuucuuua       60

ucagccccuc agcacuggag uugcccagag ggcacacugg cugggaacgg aaauagcacu      120

uguguggguc cggcacccuu ccuaauauuu ucccauggca acucuaucuu cagaauugac      180

acggaaggga ccaauuacga gcaacucgua guggacgccg gagucucggu gaucauggac      240

uuucacuaua acgaaaagag gauuuacugg guugaucugg agcggcagcu ucugcagcgc      300

guguucuuga auggcucacg acaggaacgu gucugcaaca ucgagaagaa ugugagcggu      360

auggcgauaa acuggaucaa ugaggaagua auuuggagua accaacagga ggggaucauu      420

acaguuacug acaugaaagg aaauaacucc cauauccucc ugucugcucu gaaguauccu      480

gccaaugugg cagucgaucc aguggaaaga uuuauauucu ggagcuccga gguggccggc      540

ucacucuaca gggcugacuu agauggcguc gggguuaaag cacugcuuga gaccagugaa      600

aagauuacag ccgugagcuu ggacguacug gauaagcggc uauuuuggau ccaguauaac      660

cgcgagggau cuaauucccu cauuuguuca ugcgacuacg augguggcag cgugcacauc      720

aguaaacauc ccacccagca caaccuguuc gcuaugucuc uuuuugggga cagaaucuuc      780

uauuccacuu ggaagaugaa aacaauuugg auagccaaca agcacaccgg aaaagauaug      840

gucaggauca aucugcauag cucguuugug ccuuugggcg aacucaaggu ugugcaccca      900

cuggcgcaac ccaaggcaga ggacgacacg ugggaaccug agcagaaauu auguaagcug      960

cggaaaggua acugcucauc cacugucugu gggcaggauc uccagucaca ucuuugcaug     1020

ugugccgagg gauacgcucu gagucgcgac cgaaaguacu gcgaagaugu gaaugagugu     1080

gccuucugga accacggcug caccuugggc ugcaaaaaua caccagggag cuauuacugu     1140

acuugcccgg uaggauucgu ucuacugccc gacgguaaga gaugucacca acucgugucc     1200

ugcccuagga acgucucuga auguagccau gauugcgugc ugaccucaga gggcccacuu     1260

uguuuuugcc ccgaagggag uguccuggag cgggacggaa aaacauguuc cggcugcagc     1320

ucuccugaua auggugggug uucacaguug ugcgugccac ucagucccgu uagcugggag     1380

ugcgacuguu ucccgggcua ugaucugcag uuagacgaaa aguccugcgc agcuucugga     1440

ccucaacccu uucugcuauu cgccaacucg caggauauuc gucacaugca uuuugacggc     1500

accgacuacg ggacgcuccu gagccagcag augggaaugg uguaugcgcu ugaucacgac     1560

ccaguagaga auaagaucua cuucgcccau acugcauuga aauggauaga acgcgcuaac     1620

auggaugguu cccaaagaga gaggcugauu gaagagggcg ucgacgugcc ugaggggcuc     1680

gccguugauu ggaucggacg gcgauuuuau uggacagacc gcggcaaguc acugaucggu     1740

agaagugauc uuaaugggaa aaggucuaag auuaucacca aagaaaacau uagccagccc     1800

cggggcauag cugugcaccc aauggccaag cgccuguucu ggacugacac aggaaucaau     1860

cccagaauug aguccucuag cuugcagggc cucgggaggc uggucaucgc aucuuccgau     1920

uuaaucuggc cuaguggaau uaccauagac uuucugacgg auaagcuaua cuggugugac     1980

gccaaacaga gcgugaucga aauggcuaac cucgaugguu cuaagcgucg gcgacugacc     2040

caaaaugacg uaggccaccc auucgcggug gcaguuuuug aggacuacgu cugguucucc     2100

gauugggcca ugccgucagu gaugagagug aacaaaagga cagggaagga ccgcguccgg     2160

cuucagggaa guauguugaa acccagcucg cugguugugg ugcauccucu cgcuaagcca     2220

ggcgccgauc ccugccugua ucagaacggu gggugugagc acauuugcaa gaaaagauua     2280

ggcacugcau gguguuccug cagggaagga uuuaugaagg ccucugacgg caaaaccugu     2340

cuggcucuug augggcauca guugcucgcc ggaggcgagg uagaccugaa gaaucaaguc     2400

acaccucuag auauccugag caaaacucgc gugucagaag acaacauuac cgagagucag     2460

cacaugcucg uugcagaaau cauggugucc gaucaggacg auugcgcgcc agucgguugu     2520

ucuauguacg cucgaugcau aagcgagggg gaggacgcca caugccagug ucugaaggga     2580

uucgcaggcg augguaaacu uugcuccgac aucgacgaau gugagauggg cgugcccguu     2640

ugcccgccug ccucaagcaa auguauuaau accgaagggg gauaugugug ccgguguagu     2700

gagggcuacc aaggggaugg aauccacugc uuggacauug augaauguca gcugggcgag     2760

cauucuugcg gugagaacgc uuccuguacu aauacggaag ggggauauac augcaugugc     2820

gccggccguu uaagcgagcc aggucucauc ugucccgacu cgaccccucc cccacaccug     2880

agagaagaug accaucacua cucaguaagg aacucugaua gugagugccc ucuuucccau     2940

gacggcuauu gucugcacga uggggucugc auguacauag aagcauugga caaguacgcu     3000

uguaauugcg uggugggaua uauuggcgag cgcugucagu accgggaucu caaauggugg     3060

gagcugagac acgccgggca uggacaacag cagaagguca ucguuguggc gguaugcgug     3120

gucgugcuag uuaugcugcu ccugcuuagc uuguggggcg cccacuauua caggacucag     3180

aaacuguuau cuaagaaccc caaaaaucca uaugaagaga gcucccgaga cgugcgcuca     3240

cggagaccgg cugacaccga agaugguaug aguagcuguc cucaacccug guucgucgug     3300

auuaaggagc aucaggaccu caagaacggg ggacagccag uugcaggcga ggauggucag     3360

gccgcugacg gcucuaugca acccacaucc uggaggcagg aaccucagcu gugcgggaug     3420

ggaaccgagc agggcuguug gaucccagug ucaagugaua aagggagcug cccccaaguc     3480

auggaacguu ccuuucacau gccuucuuac ggaacucaga cacuugaggg cgguguagaa     3540

aagccgcauu cgcugcuaag cgccaaucca cucuggcagc aacgcgcacu ggaucccccu     3600

caccagaugg aguugacgca guga                                            3624


<210>  448
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  448
augaccgccg gcagaaggau ggagaugcug ugcgcugggc gggugcccgc acuccuucug       60

uguuugggau uccacuuacu gcaggccguc cuaagcacaa cuguuauccc uuccugcauu      120

ccaggugaau cuucagacaa cuguacggcg cucgugcaaa ccgaggauaa uccgcgcgua      180

gcucagguga guauaacaaa gugcagcucc gacaugaacg gcuacugucu gcaugggcag      240

ugcaucuauc uugucgauau gucucagaau uacugucgau gcgaaguggg auauacuggc      300

guucguugug agcacuuuuu ccugaccgug caucaacccu ugucgaaaga auacgucgcc      360

cucacaguga uucugaucau ucuguuucuc aucaccguag uugguucaac uuauuacuuc      420

ugcagauggu auaggaaccg caagagcaaa gagccuaaga aagaguacga acgggugaca      480

aguggggacc cagaguuacc ccaggucuga                                       510


<210>  449
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  449
auggccgagg gcgaaaucac cacauucacu gcucugacgg agaaguuuaa ccuucccccu       60

gggaauuaca aaaagccaaa acuccuguau ugcagcaacg gaggucacuu cuugagaauu      120

uuaccggacg gcaccgugga ugggacaagg gaccgguccg aucagcauau acaacugcag      180

cuaucugcag aaucagucgg agagguuuac aucaagagua cugaaaccgg ccaguaucuc      240

gccauggaca cagauggucu gcuuuacggg agccagaccc ccaaugagga gugucuguuu      300

uuggaacgcc ucgaggaaaa ccacuauaau acuuacauuu ccaaaaagca ugcggagaag      360

aacugguucg ugggacugaa aaagaauggc ucuugcaaac gaggcccucg uacacacuau      420

gggcaaaagg cuauccuguu ucucccauua cccguaucgu cagacuga                   468


<210>  450
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  450
auggugggcg ucgggggagg ugacguugag gaugugaccc ccagaccugg cgggugccag       60

aucagcggaa ggggcgcccg ggguuguaac gggauuccag gagcugcagc cugggaagcg      120

gcucugccgc gccgacgucc cagaaggcac ccuuccguaa auccacgguc ucgcgccgca      180

ggcucaccca gaacaagggg ccggcgcacu gaggaacgac cuagugggag cagacucgga      240

gacagggguc ggggccgugc ccuuccaggg ggacgccugg gcgguagagg gaggggacgg      300

gcucccgagc gagugggcgg ccgcgggaga ggaaggggua cggcagcccc ucgggcugcc      360

ccagcggcac gcggcuccag accggggccc gccggaacca uggcugccgg cucuauaaca      420

acuuugccug cauuaccaga agaugguggg ucgggcgcuu uucccccugg acauuucaag      480

gacccaaaaa ggcuguacug caagaacggc ggguucuuuc uacguaucca ccccgaugga      540

cgggucgacg gugugcgaga gaaaucagau ccgcauauua agcuccaacu gcaggccgag      600

gaaagaggcg uugugagcau caaagggguc ugugcgaaua gguaucuugc caugaaggag      660

gacggacgcc uguuggcaag uaagugcgug accgaugaau guuucuuuuu cgagcggcuc      720

gaguccaaca auuacaacac auauagaucu aggaaauaca ccagcuggua uguagcucug      780

aagcgcacug gccaguacaa acuggguucc aagacagggc cuggccagaa agccauucuc      840

uuuuuaccca ugucagcuaa gaguuga                                          867


<210>  451
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  451
augcacaagu ggauccugac cuggauucuc cccacacuuc uguacagaag cugcuuccau       60

auaaucuguu uggugggcac uauuuccuua gccugcaacg acaugacgcc ugagcagaug      120

gcuaccaaug ucaacuguuc uucaccagaa aggcacacac ggaguuauga uuacauggag      180

ggaggagaca uccgcguucg acgucuguuu ugcagaacuc aaugguaucu aaggauugau      240

aaacggggua aggugaaagg cacccaggaa augaagaaua acuacaauau cauggagaua      300

cgcacaguag caguggggau cgucgccauu aaaggagugg aaagcgaguu cuaucucgcg      360

augaacaagg agggcaagcu guacgcuaaa aaggaaugua augaggacug caacuuuaaa      420

gaacuuaucc uggagaauca uuauaacacc uacgccuccg caaaguggac ucacaauggu      480

ggggagaugu ucguugccuu gaaccagaaa gggauuccgg ugagaggcaa gaagaccaaa      540

aaggaacaga aaacagcuca uuuucucccc auggcaauca cguga                      585


<210>  452
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  452
augaagcugc uccccagcgu gguccuuaaa cuguucuugg ccgcuguuuu auccgcacug       60

gugaccggcg agucucuaga aagacucagg cgggggcugg ccgcgggaac aucaaacccu      120

gacccaccga cuguaaguac ggaucagcuu cugcccuugg guggcgggcg cgaccgaaag      180

gugcgugauc uccaagaggc ugaccuggau cugcucagag ucaccuuaag cuccaaaccu      240

caggcccugg caacaccaaa uaaggaggaa cacggaaaaa ggaagaagaa aggcaagggu      300

cuugggaaaa agcgggaccc cugcuugcgc aaauacaagg auuuuuguau ccauggagaa      360

ugcaaguaug ugaaagagcu gagagccccu ucuuguauuu gccacccagg cuaccauggc      420

gagagguguc acgggcuauc gcuccccguu gaaaaccggc uguauacuua cgaccauacc      480

acaauacuug cuguggucgc agugguacug ucaagcguuu gcuugcucgu gaucgucgga      540

cuguuaaugu uccgcuauca ccgaagaggu ggcuacgaug uggagaauga agagaaggug      600

aaacugggga ugaccaacag ucacuga                                          627


<210>  453
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  453
auguggguga ccaagcugcu ccccgcccuu cuguugcagc acgucuuacu gcaucuacuc       60

cugcuuccua ucgcuauucc auacgcagag ggccaaagaa aaaggcggaa cacaauacac      120

gaguucaaga aaagcgccaa gacuacgcug aucaaaauug acccggcguu gaagaucaag      180

accaaaaagg uuaauacagc ugaucagugc gccaaccgcu guacucgaaa uaaagggcuc      240

cccuuuaccu gcaaggcauu cguguuugac aaagcccgua agcagugucu gugguucccu      300

uuuaacucca ugucuucagg aguaaagaaa gaguucgguc augaauuuga ucuguaugag      360

aauaaggacu acauuagaaa cugcaucaua ggcaaaggga ggaguuauaa gggaacagug      420

agcaucacca aauccggcau uaagugucag ccauggucuu cgaugauccc ccacgaacau      480

ucauuccucc cuagcaguua ccgggguaaa gauuuacaag agaauuauug ccgcaaccca      540

agaggggagg aaggaggccc cugguguuuu acuuccaauc cugaggucag guacgaagug      600

ugcgacauuc cacaguguuc ugagguugag ugcaugacau guaacggcga aagcuaucgg      660

gggcugaugg aucacaccga guccggaaag aucugccagc gcugggacca ccagacgccg      720

caucgacaca aguuccuucc cgaaagauac ccugauaaag guuuugacga uaauuacugc      780

aggaacccag acggccaacc ccggccuugg uguuauacuu uggauccaca uacccguugg      840

gaauacugcg cuauaaagac augugcagac aauacuauga acgacaccga ugugccccug      900

gaaacaaccg agugcauuca ggggcaggga gagggcuauc gcgguacggu caauacuauc      960

uggaacggga uuccguguca gagaugggac ucacaauacc cucacgaaca cgauaugaca     1020

cccgagaacu ucaaaugcaa ggaccuaagg gaaaauuauu gucggaaccc agauggaagu     1080

gagagcccuu ggugcuuuac cacugacccc aauauccgag ugggcuacug uucucagauc     1140

ccaaacugcg auauguccca uggccaggac uguuaucgcg ggaaugguaa aaacuacaug     1200

ggaaaucucu cacaaacaag aagcggccug accugcagua ugugggauaa gaacauggaa     1260

gaccuucaca ggcauauuuu cugggagccc gaugccucua agcugaauga gaacuacugc     1320

cggaauccug acgacgaugc ucacgggcca ugguguuaua cgggaaaccc guugauaccc     1380

ugggacuacu gcccuaucuc ccgcugugaa ggcgauacca caccaacuau uguaaaucuc     1440

gaccaucccg uuaucagcug cgccaaaacc aagcagcuga gaguggucaa cgguauaccu     1500

acaaggacua auauugggug gauggugucg uuacguuauc ggaacaaaca caucuguggc     1560

ggaucucuga ucaaggaguc cugggugcuc accgcgcgac agugcuuccc aucaagagau     1620

cuuaaagacu acgaagcaug gcugggcauu cacgaugucc augggagggg agacgagaag     1680

uguaagcagg uuuugaacgu gagucagcua guauaugguc ccgaaggcag cgaucuggug     1740

cucaugaaac uggcccgccc ggcuguccuu gacgauuuug uguccacaau cgaccugccu     1800

aauuacgggu gcaccauucc agagaagacu ucuuguagcg uuuauggaug gggcuacacg     1860

gguuugauaa acuacgaugg gcuccugcgg guggcccacu uauauaucau gggcaaugag     1920

aaaugcucac aacaucacag aggaaagguc acacugaacg aaagugagau uugugcaggc     1980

gcugagaaaa ucggguccgg acccugcgaa ggugacuacg gcgggccucu agugugcgag     2040

cagcacaaga ugaggauggu acucggaguu aucgugcccg gccgcgguug ugccauucca     2100

aaucgaccug ggauauucgu ccggguggcg uauuacgcca aguggaucca uaaaauuauc     2160

cugaccuaua agguccccca gagcuga                                         2187


<210>  454
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  454
auggccaagg cugcagccau cggcauugac cuggggacca cauacagcug cgugggaguc       60

uuccagcacg guaaaguuga gauaaucgcg aacgaucaag gcaauagaac uacgcccucc      120

uauguggcuu uuaccgacac agaaaggcuc auuggggaug ccgcaaagaa ccagguagcc      180

cuuaauccuc agaacacugu guucgacgcu aaacggcuga ucggacgcaa guuuggcgau      240

ccagucgugc agucugacau gaaacauugg ccguuccaag uuauuaauga uggugacaag      300

cccaaggugc aggucucaua caaaggggag accaaggcau uuuauccuga agagaucagu      360

agcauggugu ugacaaaaau gaaggaaaua gccgaggcuu acuuaggaua uccaguaacc      420

aacgccguua ucacugugcc cgcguacuuc aaugauuccc agcgacaggc aacaaaagac      480

gccggcguca uugcuggccu gaacgugcua cguaucauua augagccuac cgccgcagcu      540

aucgccuaug ggcucgauag aacgggaaag ggugaaagga acgugcugau auuugaccuu      600

ggcgggggaa cuuucgaugu cucuauucug accaucgacg acggcauuuu ugagguuaag      660

gcgacagccg gugauacuca ccuuggggga gaagacuucg auaaucggcu cgugaaccau      720

uuuguagagg aguucaaacg caagcacaaa aaggacaucu cgcaaaauaa aagagcagug      780

aggcggcugc gcaccgcuug ugaacgagcc aagagaacac ugucaagcag uacccaggcu      840

ucccucgaga ucgauucuuu auuugaaggc auugacuucu acacgagcau aacuagggcc      900

cgguucgagg aacugugcuc cgaucuuuuu cguucaacau uggagccagu cgagaaagca      960

cugcgcgacg ccaagcuaga uaaggcucag auccaugacc ucgugcuggu uggcgggagu     1020

acccggauuc ccaaagugca gaaguugcug caagauuucu uuaacggaag ggacuugaau     1080

aaaagcauca acccugacga agcggucgca uacggugccg cugugcaggc cgcaauacuc     1140

augggcgaua agucugagaa cguacaggac cuguuacugc ucgauguugc cccacuuucc     1200

cugggguugg aaacugcugg aggcgugaug acagcccuaa uuaaaagaaa uucaaccauc     1260

ccgacgaagc aaacccagau cuucacaacu uauagcgaca accagcccgg uguccugauu     1320

cagguguacg agggggaacg agcaaugacc aaggauaaua accuccuggg ccgcuuugag     1380

cuuaguggaa ucccuccagc gcccagaggc gucccucaaa uugaggugac auucgacaua     1440

gaugcuaaug ggauccugaa cguuacugcc accgacaaau cuacaggaaa ggcaaauaaa     1500

auuaccauca cuaacgauaa ggguagguug uccaaagaag agaucgaacg gauggugcag     1560

gaggccgaaa aguauaaggc ugaggacgag guacagcgcg aaagagucag cgccaaaaau     1620

gcacucgagu cguacgcuuu uaacaugaag ucugccgugg aagaugaggg ccugaaaggg     1680

aagauuuccg aggcggacaa aaagaagguu uuagauaaau gucaggaagu gauaucaugg     1740

cuggacgcca auacgcuagc ugagaaggac gaguucgaac acaaaaggaa ggaacucgag     1800

caagucugca acccaaucau uaguggacug uaucagggcg ccggugggcc cggcccggga     1860

ggcuuugggg cacagggacc uaaagguggc agcggguccg gacccacaau cgaggaagug     1920

gauuga                                                                1926


<210>  455
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  455
auggccaagg cugcagccau cggcauugac cuggggacca cauacagcug cgugggaguc       60

uuccagcacg guaaaguuga gauaaucgcg aacgaucaag gcaauagaac uacgcccucc      120

uauguggcuu uuaccgacac agaaaggcuc auuggggaug ccgcaaagaa ccagguagcc      180

cuuaauccuc agaacacugu guucgacgcu aaacggcuga ucggacgcaa guuuggcgau      240

ccagucgugc agucugacau gaaacauugg ccguuccaag uuauuaauga uggugacaag      300

cccaaggugc aggucucaua caaaggggag accaaggcau uuuauccuga agagaucagu      360

agcauggugu ugacaaaaau gaaggaaaua gccgaggcuu acuuaggaua uccaguaacc      420

aacgccguua ucacugugcc cgcguacuuc aaugauuccc agcgacaggc aacaaaagac      480

gccggcguca uugcuggccu gaacgugcua cguaucauua augagccuac cgccgcagcu      540

aucgccuaug ggcucgauag aacgggaaag ggugaaagga acgugcugau auuugaccuu      600

ggcgggggaa cuuucgaugu cucuauucug accaucgacg acggcauuuu ugagguuaag      660

gcgacagccg gugauacuca ccuuggggga gaagacuucg auaaucggcu cgugaaccau      720

uuuguagagg aguucaaacg caagcacaaa aaggacaucu cgcaaaauaa aagagcagug      780

aggcggcugc gcaccgcuug ugaacgagcc aagagaacac ugucaagcag uacccaggcu      840

ucccucgaga ucgauucuuu auuugaaggc auugacuucu acacgagcau aacuagggcc      900

cgguucgagg aacugugcuc cgaucuuuuu cguucaacau uggagccagu cgagaaagca      960

cugcgcgacg ccaagcuaga uaaggcucag auccaugacc ucgugcuggu uggcgggagu     1020

acccggauuc ccaaagugca gaaguugcug caagauuucu uuaacggaag ggacuugaau     1080

aaaagcauca acccugacga agcggucgca uacggugccg cugugcaggc cgcaauacuc     1140

augggcgaua agucugagaa cguacaggac cuguuacugc ucgauguugc cccacuuucc     1200

cugggguugg aaacugcugg aggcgugaug acagcccuaa uuaaaagaaa uucaaccauc     1260

ccgacgaagc aaacccagau cuucacaacu uauagcgaca accagcccgg uguccugauu     1320

cagguguacg agggggaacg agcaaugacc aaggauaaua accuccuggg ccgcuuugag     1380

cuuaguggaa ucccuccagc gcccagaggc gucccucaaa uugaggugac auucgacaua     1440

gaugcuaaug ggauccugaa cguuacugcc accgacaaau cuacaggaaa ggcaaauaaa     1500

auuaccauca cuaacgauaa ggguagguug uccaaagaag agaucgaacg gauggugcag     1560

gaggccgaaa aguauaaggc ugaggacgag guacagcgcg aaagagucag cgccaaaaau     1620

gcacucgagu cguacgcuuu uaacaugaag ucugccgugg aagaugaggg ccugaaaggg     1680

aagauuuccg aggcggacaa aaagaagguu uuagauaaau gucaggaagu gauaucaugg     1740

cuggacgcca auacgcuagc ugagaaggac gaguucgaac acaaaaggaa ggaacucgag     1800

caagucugca acccaaucau uaguggacug uaucagggcg ccggugggcc cggcccggga     1860

ggcuuugggg cacagggacc uaaagguggc agcggguccg gacccacaau cgaggaagug     1920

gauuga                                                                1926


<210>  456
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  456
auggccaccg cuaagggcau cgcaauuggg auagaccugg gaacaacuua cagcugcgug       60

ggugucuucc agcacggcaa aguugagauc auugccaacg aucaagggaa uagaacgacc      120

cccuccuaug uggcguuuac agacacugaa aggcucaucg gagaugcugc caagaaccag      180

guagcaauga auccucagaa caccguguuc gacgccaaac ggcuuauugg ccgcaaguuu      240

aaugauccag ucgugcaggc ugacaugaaa cuguggccgu uccaaguuau caacgagggu      300

gggaagccca agguguuggu cucuuacaaa ggagaaaaua aggcauuuua uccugaggaa      360

auaucaagua ugguguuaac aaaacugaag gagaccgccg aggcuuuccu aggccaucca      420

guaacuaacg ccguuaucac agugcccgcg uacuuuaaug auagccagcg acaggcaacc      480

aaagacgccg gcgucauugc ugggcucaac gugcugcgua ucauuaauga accuacggcc      540

gcagcuaucg ccuauggacu ugauaagggu ggccaggggg agagacacgu gcugauauuc      600

gacuugggag gcgguacuuu ugaugucucc auucucacca ucgacgaugg gauuuucgaa      660

guuaaggcga cagccggaga cacucaucug ggcggcgagg acuuugauaa caggcuggug      720

ucucacuucg uagaggaauu uaaacggaag cauaaaaagg acaucucgca aaauaaacgc      780

gcagugagaa ggcuccggac cgcuugugag cgcgccaagc gaacauuauc aagcaguacc      840

caggcuaacc uggaaaucga uucccuuuac gaggggauug acuucuauac gucuauaacu      900

agagccaggu ucgaagaguu gugcgcagau cuguuucggg gaacacuaga gccagucgaa      960

aaagcccucc gugacgcuaa gauggauaag gcgaaaaucc acgacauugu gcugguuggu     1020

ggcagcaccc gcauccccaa ggugcagaga cuucugcagg auuacuucaa ugggagggac     1080

uugaacaaau ccauaaaccc ugaugaggca gucgccuacg gagcugccgu gcaagcagcc     1140

auucucaugg gcgacaaguc agaaaaagua caggaccugu uacugcucga uguugcucca     1200

cuuagucugg guuuggagac ugccgggggc gugaugacag cacuaaucaa gcggaauagc     1260

accaucccga cgaagcagac ccaaauuuuu acaacuuauu cugacaacca gcccggaguc     1320

cugauccagg uguacgaagg cgagcgagcg augaccaaag auaauaaccu ccuggggcgc     1380

uucgaccuua cagggauucc uccagcuccc agaggugucc cucagauaga ggugacuuuu     1440

gauaucgacg ccaauggcau ucugaacguu accgcaacag auaaguccac cgggaaagug     1500

aauaagauca cuaucacgaa cgacaaagga agguugucaa aggaagagau ugaacggaug     1560

guacucgaug ccgagaagua uaaagcugaa gacgaggucc aacgcgagaa gauagccgcu     1620

aaaaaugcac uggaaagcua cgccuucaac augaagagug ugguuucuga ugagggcuua     1680

aaagguaaga ucuccgaaag cgacaagaau aaaauucugg auaaguguaa cgagcuacuc     1740

ucguggcugg aggugaauca gcuugcggaa aaagacgagu uugaccacaa gagaaaagaa     1800

uuggagcaga ugugcaaccc aaucauuaca aagcuguauc agggaggcug uaccggaccc     1860

gccugcggca cuggguacgu cccgggaagg ccugcuaccg gucccacaau cgaagaggug     1920

gauuga                                                                1926


<210>  457
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  457
augagcgcca gaggccccgc uaucgggauu gaccugggaa ccacauacuc cugcgugggu       60

gucuuccagc acggcaaggu ugagauaauc gcaaacgauc aagggaauag gacuacgccu      120

ucuuaugugg ccuuuaccga cacagaacgg cucauuggag augcggcuaa aaaccaggua      180

gccaugaauc caacuaacac caucuucgac gcaaagcgcc uuauuggccg aaaauuugag      240

gaugccacag ugcagucaga caugaagcau uggccguucc gugucgugag ugaagguggg      300

aaacccaagg uucaggugga guacaaggga gaaaccaaaa cauuuuuccc ugaggagauc      360

agcuccaugg uccugacuaa gaugaaagaa auagcugagg cauauuuggg cggcaaggug      420

cacucugccg uaaucaccgu uccagcuuac uuuaaugauu cgcaaagaca ggccacgaaa      480

gacgcgggga cuauuaccgg auuaaacgug cugaggauca uuaaugaacc cacagcagcc      540

gcuaucgccu auggucuaga uaagaagggc ugugcagggg gagagaaaaa cguccucaua      600

uucgaccugg gcggugggac uuuugaugug ucaauucuua ccaucgagga cggaauuuuc      660

gaagucaaga gcacagcugg cgauacccau cugggcgggg aggacuuuga caaucggaug      720

gugagucacu uggccgaaga guucaaacgc aagcauaaaa aggauaucgg accuaacaaa      780

agagcgguua ggcggcuccg cacggccugc gaacgagcaa agagaacucu guccucuagc      840

acacaggcuu ccaucgagau ugacucacug uacgagggug uggauuuuua uaccaguaua      900

acuagggccc gguucgagga acucaaugcu gacuuauucc guggcacacu ggaaccagua      960

gagaaggccc uucgcgaugc aaaauuggac aaggggcaga uccaagaaau ugugcugguc     1020

ggaggcagca ccagaauccc caaaauacag aagcuacucc aggacuuuuu caacgguaaa     1080

gagcugaaua agucuauuaa cccugaugag gccguggcuu acggggcggc aguucaggcc     1140

gcuauccuua ucggcgauaa guccgaaaau gugcaagacc uguugcuccu ggaugucacg     1200

ccauuaucac ugggaauuga gaccgccggc ggggugauga caccgcucau caaaaggaac     1260

acuaccauuc ccacaaagca gacucagacc uuuacaaccu acagcgacaa ccaaaguucu     1320

guacuuguuc agguguauga aggagagcgg gcaaugacua aagacaauaa ccuguugggu     1380

aaguucgauc uaacgggcau accuccagcu ccccgagggg ucccucagau cgaagugaca     1440

uuugacauug augccaaugg aauccugaac gucaccgccg cagacaaauc cacuggcaag     1500

gagaauaaga ucaccauuac aaacgauaaa ggucgccuca gcaaggacga uauagacaga     1560

auggugcagg aggcggaaag guacaaaucg gaggaugaag cuaaucggga ccgcguugcc     1620

gcaaagaacg cccuggaguc uuauaccuac aauaucaaac aaacugugga ggaugaaaaa     1680

cuuagaggga agauuuccga gcaggacaag aacaagaucc uggauaaaug ucaggaagua     1740

auuaauuggu uggacaggaa ccagauggcu gagaaggacg aauaugagca caaacaaaag     1800

gagcucgaac gugucugcaa uccaaucaua ucaaaacugu accagggcgg acccggcggg     1860

ggaaguggug gcgggggaag cggcgccucc ggugggccga caaucgagga aguggauuga     1920


<210>  458
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  458
augagcgugg ucggcaucga ccugggguuc caguccugcu acguugccgu ggcuagagca       60

ggagguauug agaccauagc caacgaauau ucugauaggu guacacccgc gugcaucuca      120

uuuggcccua agaaucggag uauuggggcu gccgcaaaaa gccaaguaau cuccaacgcc      180

aagaauacug ugcagggauu caaacgcuuu cacggccgag cuuucucuga cccauuuguc      240

gaggcagaaa agucgaaccu cgccuacgau auugugcagc uuccgacggg ucugaccggg      300

aucaaaguua cauauaugga ggaagaacgu aauuucacua ccgaacaggu gacagcuaug      360

uuguuaucaa agcugaagga aaccgccgag agcguccuca aaaagcccgu gguagacugu      420

guugugagug ucccuugcuu uuacacugau gcggaaagaa gguccgugau ggacgcaaca      480

caaauagccg gacuaaacug ucugcggcuu augaaugaga ccacggcugu ggcccuggca      540

uauggcaucu acaaacagga uuugccagcu cucgaggaaa agccccgcaa cgucguuuuc      600

guggacaugg gccauucugc cuaucaggua agcgugugcg cguuuaauag agggaaacug      660

aagguccugg ccacugcauu cgauaccaca cucggaggua ggaaguuuga cgagguguua      720

guuaaccacu ucugugaaga guuuggcaaa aaguacaaac uggauauuaa guccaaaauc      780

cgggcucuuu ugcgccuguc acaggaaugc gagaagcuca aaaagcuaau gagugccaau      840

gcuagcgacc ugccucuuuc uauugagugu uucaugaacg auguggacgu cuccgggacu      900

augaaucgag gaaaguuccu ggaaaugugc aacgacuugc ucgccagagu ggagccaccc      960

cugaggucag uauuagaaca aaccaaacug aagaaagagg auaucuacgc aguugaaaua     1020

gugggcggug ccacacggau uccugcuguc aaggagaaaa ucagcaaguu uuucgggaag     1080

gagcucagua ccacgcuuaa ugcggacgaa gcagugacuc guggaugugc ccugcagugc     1140

gcuauuuugu cuccagccuu uaaaguccgc gaguucucca ucacagaugu gguuccguau     1200

cccaucagcc uaagauggaa cucgccugca gaagaggggu cuuccgacug cgaaguguuu     1260

ucaaagaacc augccgcucc auucaguaaa guacugaccu uuuacaggaa ggagcccuuc     1320

acucucgagg ccuauuacag cuccccucag gaucugccau aucccgaccc ggcaauugcg     1380

caguuuucug uccaaaaagu gacaccucag agcgauggcu caaguuccaa gguuaaggug     1440

aaaguccggg ugaauguaca cggcauauuc agcgugucuu cagcuagucu uguugaaguc     1500

cauaagagcg aggaaaacga ggagcccaug gaaaccgacc agaaugccaa agaggaagag     1560

aagaugcaag uggaucagga ggagccacac guggaggaac agcagcaaca gacgccugca     1620

gagaacaaag ccgaauccga ggaaauggag accucucagg cuggaucgaa ggacaagaaa     1680

auggaucagc ccccacaagc caagaaagca aaggucaaaa caagcacugu ugaccugccc     1740

aucgagaauc aguugcucug gcagauugac cgagaaaugc ugaacuuaua caucgagaau     1800

gaagguaaga ugauaaugca ggauaaacug gagaaggaac gcaacgacgc uaagaaugcc     1860

guggaggagu auguguacga aaugagagau aaacuauccg gcgaguacga aaaguuugua     1920

ucagaggacg auaggaacag uuucacccuc aaacuggagg acacagaaaa uuggcuuuau     1980

gaggaugggg aagaccaacc uaagcagguc uacguggaua aauuggcgga gcugaagaac     2040

cucggacagc caauuaagau ccgguuucag gaaucugagg agcgcccgaa acuguucgag     2100

gagcuuggca agcaaaucca gcaguauaug aaaauuauca gcuccuucaa gaauaaagaa     2160

gaccaauacg aucaccugga cgccgcugau augacuaagg uugagaaguc aaccaacgaa     2220

gcaauggagu ggaugaauaa caaauugaac cuccagaaua agcagagccu gacaauggac     2280

cccgugguca aaucuaagga gauugaagcc aaaauaaagg aguuaaccuc cacuuguagu     2340

ccuaucauua gcaagccaaa acccaaggug gaaccuccaa aagaggaaca gaagaacgcu     2400

gagcaaaaug gucccguuga cgggcagggc gauaacccgg gaccucaggc cgcagagcag     2460

ggcacggaca cagcggugcc aucugauucc gacaaaaagc ugcccgaaau ggauaucgac     2520

uga                                                                   2523


<210>  459
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  459
augagcgugg ucggcaucga ccugggguuc cucaacugcu acauugccgu ugcuagaucc       60

ggagguauag agaccaucgc aaaugaauau ucugauaggu guacacccgc cugcauuuca      120

cuuggcaguc ggacucgcgc gaucgggaac gcugccaaga gccagauugu gacgaaugua      180

cgaaacacca uccacggauu uaaaaagcug cauggccguu ccuucgacga uccuauagug      240

caaacagaga gaaucagguu gccauacgaa uuacagaaaa ugccgaaugg uucugcaggg      300

gucaaggugc gguaucugga ggaagagaga cccuuugcca uugagcaggu uacuggaaug      360

cuacucgcua aacugaagga aaccucggag aacgcacuua agaaaccugu ggccgacugu      420

gucaucucaa uucccagcuu cuuuacagau gcugaaagaa ggagugugau ggccgcggca      480

cagguagccg gccugaauug cuugcggcuc augaacgaga ccacugcugu ugcccuggca      540

uacggcaucu auaagcaaga ccugccaccu cucgaugaga aaccacgcaa uguggucuuc      600

auagacaugg ggcacuccgc uuaccaggug uuagugugug ccuuuaacaa gggaaaacug      660

aagguccuug cgacaaccuu cgaucccuau uuggguggcc gaaauuuuga cgaagcccug      720

guugauuacu ucugcgacga guuuaagacg aaauacaaga uuaacgugaa agaaaauucu      780

agagcacuac ucaggcugua ucaggagugu gaaaaacuua agaagcugau gagcgcuaac      840

gccuccgauu ugccucucaa uaucgagugc uucaugaacg accuggacgu aucaaguaaa      900

augaaccggg cucaguuuga gcaauuaugu gccagccugc ucgcacgugu ggaaccaccg      960

cuuaaggccg ucauggagca ggcuaaucug cagcgcgaag auauuucuuc caucgagauc     1020

guugggggag cgacucgcau ucccgcagug aaggaacaga uaaccaaauu cuucuugaag     1080

gacaucucaa caacucuaaa cgccgaugag gcuguggcca ggggcugcgc acugcaaugu     1140

gccauucuca gcccugcuuu uaaaguccgg gaguucagua ucaccgaccu ggugccauac     1200

ucuauaacac uucgauggaa gaccuccuuu gaagauggua gcggggagug cgaaguauuc     1260

ugcaaaaauc aucccgcccc uuuuucgaag guuauuacgu uccacaagaa agagccauuu     1320

gaacuggagg cauucuauac uaacuugcau gaggugcccu acccggacgc gcgcaucgga     1380

ucuuuuacaa uccagaaugu cuucccucag uccgauggcg acucaaguaa ggugaaaguc     1440

aaggugagag uuaacauuca cggcaucuuu agcguggcuu ccgccucugu aauugaaaaa     1500

caaaaucucg agggggauca cagcgacgca cccauggaaa ccgagacuuc auucaagaac     1560

gagaauaagg auaacaugga caaaaugcag gucgaccagg aagagggaca ucagaagugu     1620

cacgccgaac auacaccaga ggaagagaua gaucacaccg gugcuaaaac gaagagugcc     1680

guguccgaca aacaagauag gcugaaucag accuuaaaga agggcaaagu uaagagcauc     1740

gaccugccua uucagucuuc acuaugccgg cagcucgggc aagaucugcu uaacaguuau     1800

aucgagaaug aaggaaaaau gaucaugcag gacaaguugg agaaagaacg caacgaugca     1860

aagaaugcug uggaggaaua cgucuaugac uuuagagaua ggcugggcac aguguacgag     1920

aaauucauua cucccgagga ccucagcaag cuguccgccg uacuugaaga uaccgagaac     1980

uggcuguacg aagacgguga ggaucagcca aaacaggugu auguugacaa guugcaagaa     2040

cucaagaaau acgggcagcc cauacagaug aaguauaugg agcacgagga acguccuaaa     2100

gcgcugaacg acuuaggcaa gaagauccag cuggucauga aagugauuga ggccuaccgg     2160

aauaaggaug aacgauauga ccaucuagau ccaacagaga uggagaaagu ggaaaagugu     2220

aucucugacg cuaugucgug gcucaacagc aaaaugaaug cacaaaacaa gcugucccuu     2280

acucaggauc cggucguuaa ggugucagag auuguggcca aaaguaagga auuggacaau     2340

uucugcaacc ccaucauaua caaaccuaag ccaaaagcug agguacccga agauaagccu     2400

aaggccaauu cugagcacaa cggaccaaug gacggccaga gcgggaccga gacaaaaucc     2460

gauucaacca aggacagcuc ucaacauacu aaauccagug gagaaaugga ggucgauuga     2520


<210>  460
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  460
augaagcuga gccucguggc cgcuaugcuu cuguuguuau ccgcagccag agcggaggaa       60

gaggacaaaa aggaagaugu cggcaccguu guggggaucg accugggaac aacuuacucu      120

ugcguaggug uguucaaaaa cggcaggguc gagauuauag cuaaugauca ggggaaccgg      180

aucacgcccu cauauguggc cuuuaccccu gaaggagagc gccuaauugg cgacgcagcc      240

aagaaucaac ucacaaguaa cccagagaau acuguuuucg augcuaaacg acugaucggu      300

cguaccugga acgacccgag cgugcagcag gauauuaagu uucuucccuu caaggucgug      360

gaaaagaaga caaaaccuua cauccaggua gacauagggg gaggccaaac caagacuuuu      420

gcaccagagg aaaucuccgc caugguucug acaaaaauga aggagaccgc ugaggccuau      480

uugggcaaga aagugacgca cgcggucgug acugugcccg cauacuucaa ugaugcccag      540

agacaggcua ccaaggacgc cgggacaauu gcaggacuca acgucaugag gaucauuaau      600

gaaccuacug cugccgcgau cgccuauggu cuggauaaac gggagggcga aaagaacaua      660

cugguuuuug accucggggg aggcaccuuc gaugugucuu uacugacaau ugacaauggu      720

guauuugagg uggucgcaac caacggggac acgcaucuug gaggcgaaga uuucgaccag      780

cgcgugaugg agcacuuuau caaauuguac aagaaaaaga cuggcaagga uguuagaaaa      840

gacaauaggg cugugcaaaa gcugcggcgc gaggucgaaa aagccaagcg agcucuaucg      900

ucacagcauc aggccagaau ugagaucgaa ucuuucuaug agggggaaga uuuuagugag      960

acacucacca gggcaaaauu cgaggaacug aacauggacc uuuuccgguc cacuaugaag     1020

ccagugcaga agguacugga ggauucugac uugaaaaaga gcgauaucga cgaaauuguu     1080

cucgugggag guuccacacg uauacccaaa auccaacagc uggucaagga guuuuucaau     1140

ggcaaagaac cuucacgcgg gauuaaccca gaugaggccg uggcuuacgg agcggcaguc     1200

caggccggcg uguuaagugg ugaccaagac accggggauc ugguucuccu ugacgugugu     1260

ccgcugacgu ugggcaucga gaccguagga ggcgucauga caaagcuaau acccagaaac     1320

acugugguuc cuaccaagaa aagccagauu uuuagcacag cuuccgauaa ucagccaacu     1380

gugaccauca aggucuacga aggggagagg ccccugacaa aagacaacca ccuccuggga     1440

accuucgauc uuacugguau cccuccagca ccccggggcg ugccgcagau ugaaguaacg     1500

uuugagaucg acgugaaugg gauucugcga guuacagccg aggauaaggg aaccggcaac     1560

aaaaauaaga uaacuaucac caacgaccaa aaucgcuuga caccugaaga gauugaaaga     1620

auggucaacg augccgagaa guucgcugaa gaggacaaaa agcucaaaga gaggaucgau     1680

acccggaaug aacuggaguc auaugccuac agcuuaaaga accagaucgg ugacaaagaa     1740

aagcuagggg gcaaacugag uucugaggau aaggaaacua uggagaaggc aguggaggag     1800

aaaauugaau ggcucgaauc ccaucaggac gcggacauag aggauuuuaa ggcuaaaaag     1860

aaagaacugg aggagaucgu gcagcccauu aucagcaaac uuuauggauc ggccggccca     1920

ccucccacag gggaagagga cacggcagaa aaggaugagu uguga                     1965


<210>  461
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  461
augcaggccc ccagagagcu ggcugugggc aucgaccucg ggaccacaua cagcugcguc       60

ggaguuuucc aacaggguag gguggaaauu cuugcaaacg aucagggcaa ucggacuacg      120

ccuuccuaug uagccuuuac cgacacagag cgccuggugg gggaugcggc uaagucucag      180

gccgcauuga acccacacaa uacugucuuc gacgccaaac gauuaauagg acguaaguuu      240

gcugauacca cagugcaauc agacaugaaa cauuggccgu ucagaguugu gagugaaggc      300

gguaagccca aagucagggu guguuaccgc ggggaggaua agaccuuuua uccugaagag      360

aucagcucca ugguacuguc uaagaugaaa gagacugcag aagccuaccu aggacagcca      420

guuaagcacg cugugauuac aguccccgcc uauuucaacg acucgcagcg gcaggcgacc      480

aaagaugcag gcgccaucgc uggccucaau gugcugagaa uuaucaacga gccuacggcc      540

gcagcuauag ccuacgggcu ugacaggcgg ggagcgggug aacgcaaugu gcugaucuuu      600

gauuugggcg ggggaacuuu cgacgucuca guucucagca uugaugccgg cguguuugag      660

guaaaggcaa ccgcugguga cacacaucuc gggggagagg acuucgauaa ccgacuggug      720

aaucacuuua uggaagaguu cagaaggaaa cauggcaagg accugagugg caacaagcgg      780

gccuuacguc gccugagaac ugcuugcgaa agggccaaac ggacccuuuc cucuagcaca      840

caagcaaccu uggagaucga uucccuguuu gaaggggucg acuucuauac gucaauuacu      900

cgagcccgcu ucgaggagcu auguagugau cucuuuagaa gcacacugga accaguggag      960

aaggcucuua gggacgcgaa acuggauaag gcacagaucc acgacguugu guuggucgga     1020

gguucuaccc ggauacccaa agugcagaag cuccugcagg auuucuuuaa uggcaaagaa     1080

uuaaacaagu ccauuaaucc ugacgaggcc guagcuuacg gggccgcagu ucaagccgcu     1140

gugcugaugg gagauaagug cgaaaaaguc caggaccucc uucuguugga cguggcccca     1200

cuaucacugg gccucgagac ugccgguggg gucaugacaa cccugaucca gcgcaacgcg     1260

acgauuccga ccaagcaaac acagacuuuc accacauaca gcgauaauca gcccggcgug     1320

uuuauccagg uuuaugaggg agaaagagcu augacuaaag acaacaaccu ucugggcagg     1380

uucgaguuga gugggauccc uccagcaccc cguggagugc cucaaauuga aguaaccuuu     1440

gauauagacg caaaugguau ccucucuguc acagccaccg aucgguccac uggcaaggcu     1500

aacaaaauua cgaucacaaa ugacaagggg cgacugagca aggaggaagu ggagagaaug     1560

guucacgagg ccgaacagua caaagcagag gaugaagcuc agagggaccg cguggccgcg     1620

aagaacucgu uagaggccca ugucuuccac gugaaaggau cucugcagga ggaaucccua     1680

cgggauaaga uaccagagga agacagaagg aaaaugcaag auaagugucg cgagguacuc     1740

gcuuggcugg aacauaauca gcuugcagag aaggaggaau augagcacca gaaacgagaa     1800

uuggagcaga uuugccggcc caucuuuuca cgucuguacg gcgguccggg ggugccuggc     1860

ggaaguagcu guggcaccca agccagacag ggggaccccu ccacuggacc aaucauugaa     1920

gagguugauu ga                                                         1932


<210>  462
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__P48741__HsHSPA7

<400>  462
augcaggccc ccagagagcu ggcugugggc aucgaccucg ggaccacaua cagcugcguc       60

ggaguuuucc aacaggguag gguggaaauu cuugcaaacg aucagggcaa ucggacuacg      120

ccuuccuaug uagccuuuac cgacacagag cgccuggugg gggaugcggc uaagucucag      180

gccgcauuga acccacacaa uacugucuuc gacgccaaac gauuaauagg acguaaguuu      240

gcugauacca cagugcaauc agacaugaaa cauuggccgu uccagguugu gagugaaggc      300

gguaagccca aagucagagu guguuacagg ggagaggaua agaccuuuua uccugaagag      360

aucagcucca ugguacuguc uaagaugaaa gagacugcag aagccuaccu agggcagcca      420

guuaagcacg cugugauuac aguccccacc uauuucucga acucacagcg gcaagccacg      480

aaagacgcgg gcgcaaucgc cggccucaag gugcugccua uuaucaauga ggcuacugcc      540

gcagcuauag ccuacgggcu ugaucgcaga ggagcgggua aaaggaacgu gcugaucuuu      600

gacuugggcg ggggaaccuu cgaugucagc guucucagua uugacgccgg cguguuugaa      660

guaaaggcaa cagcugguga uacucaucuu gggggagagg acuucgacaa ucggcuggug      720

aaccacuuua uggaggaguu ccgccgaaag cauggcaaag aucucuccgg caauaagaga      780

gccuuaaggc ggcugcguac cgcuugcgag cgcgccaaaa gaacaccauc uagcuccacc      840

caggcaacgc uugaaaucga cucauuguuu gagggggucg auuucuauaa gaguauuacu      900

agggcccggu ucgaagaacu guguagcgac cuauuucgau cuacacucga gcccguggaa      960

aaagcucugc gcgaugcgaa gcuggacaaa gcacagaucc acgauuucgu ucugggaggu     1020

ggcuugcacu cccauccuca gggggccgag guggcugccg gacuccugca aagacagggc     1080

gcagaacagg agcaccaacc auga                                            1104


<210>  463
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  463
augagcaagg gccccgccgu ggggaucgac cugggaacca cauacuccug cgucgguguu       60

uuccagcacg gcaaagugga gauuauagcu aacgaucaag ggaauagaac uacgccuucu      120

uauguagcau uuaccgacac agaaaggcuc aucggagaug ccgcgaagaa ccagguggcu      180

augaauccaa cuaacaccgu cuucgacgcc aaacggcuua uuggccgccg auuugaugac      240

gcagugguuc agucagauau gaagcauugg ccguucaugg uggucaauga cgccggucgu      300

cccaaagugc agguagagua caagggggaa acaaagaguu uuuauccuga ggaaguuagc      360

uccauggugc ugaccaaaau gaaggagauc gcugaggcau acuugggaaa aacugucaca      420

aacgccgugg ugaccguccc agcuuauuuc aaugauucuc aaagacaggc cacgaaggac      480

gcgggcacua uugcaggcuu aaacguucug aggaucauaa augaacccac cgccgcugcc      540

aucgcauacg ggcuagauaa aaagguggga gcugagcgga acguacucau uuuugaccug      600

gguggcggga cauucgaugu gucgauccuu acuauugaag acggaaucuu ugaggucaag      660

ucaaccgccg gcgacacaca ccuggguggg gaggauuucg acaaucgcau ggugaaccau      720

uuuauagcgg aauuuaaaag aaagcacaaa aaggauauua gcgagaauaa aagggccguu      780

cggcgcuugc gaaccgcaug ugaaagagcu aagaggacgc ucaguuccuc uacucaggcc      840

agcaucgaga uugacucccu guaugaagga aucgauuuuu acacaucaau cacccgggcu      900

cguuucgagg agcugaacgc cgaccucuuc cgcggcacuu uagauccugu ggaaaaagca      960

cugagagacg ccaaacuuga uaagagucag auucaugaca uagucuuggu gggcgggagc     1020

acaaggaucc caaagauuca aaagcugcua caggauuucu ucaauggaaa agagcucaac     1080

aagucuauca accccgacga agcuguagcg uacggugcag ccguucaggc ugccauacug     1140

uccggcgaca aaucagagaa ugugcaggau cuucuguugc ucgacgucac cccucugagc     1200

uuagggauug aaacggcagg aggcgugaug accguccuga ucaagcggaa cacaacuauc     1260

ccaaccaagc aaacacagac uuuuaccaca uauagugaua aucagccggg ugugcucauu     1320

caaguuuacg agggggagcg agccaugacc aaagacaaca aucuucuggg caaguucgaa     1380

uugacuggaa ucccucccgc uccacgcggc gugccccaga uugagguaac guuugauaua     1440

gacgccaacg ggauccuaaa ugucucugca guggauaaau ccacaggaaa ggaaaacaaa     1500

auuaccauca cuaaugacaa ggguagacug agcaaggagg auaucgaaag gaugguucag     1560

gaggcggaga aauauaaggc ugaagacgag aaacagcggg auaagguguc gucuaaaaac     1620

ucccucgaau cauacgccuu caauaugaag gcaaccgucg aggacgagaa gcugcaaggc     1680

aaaauuaacg augaagacaa gcagaaaaua cuugacaagu gcaaugagau cauuaacugg     1740

cuggauaaaa aucagacagc cgaaaaggag gaauuugagc accagcaaaa agaguuggaa     1800

aaggugugua acccuaucau uaccaagcuc uaucagagug cugggggaau gccaggcggu     1860

augcccgggg gcuucccggg aggcggggcc ccucccagcg gaggugcauc cucuggccca     1920

acuaucgagg aaguagacug a                                               1941


<210>  464
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  464
augaucagcg ccuccagagc ugcagccgcg aggcuggugg gcgcugccgc aucucggggg       60

cccaccgccg cucgccacca ggacucaugg aacggacuca gucaugaggc auuccgacuu      120

gucagccgua gagauuacgc cuccgaagcu auuaagggug ccguuguggg cauagaccug      180

gggacaacua auucuugcgu agcggugaug gagggaaaac aagcaaaggu cuuggaaaac      240

gccgagggcg cuaggacgac cccuucggug guugccuuua cagcagaugg ugaacgguua      300

guggggaugc cagcuaaacg ccaggccguc acuaauccga acaauaccuu cuaugcgaca      360

aagagacuga ucggaaggcg guacgacgau cccgaggugc agaaagacau uaagaacgua      420

ccuuuuaaga ucguucgcgc cucaaauggc gaugcauggg uggaggcuca cggcaaacua      480

uauagcccaa gucagauugg ggccuucguc cucaugaaga ugaaagaaac cgcugagaac      540

uaccugggac auacugccaa gaaugcagug aucacagugc ccgccuauuu uaacgacucc      600

caacgacagg cuaccaaaga ugcgggucag auaucuggcc uuaauguccu gagaguuauc      660

aacgaaccua cggcagccgc uuuggccuac gggcucgaca agagcgagga uaaggugauu      720

gcaguauaug accugggagg cgguacuuuc gauaucucca uucuggagau ccagaaaggg      780

guguuugaag ucaagucaac caauggagac acauuccucg gcggcgagga cuuugaucaa      840

gccuuacuga ggcacauagu gaaagaguuc aagcgggaaa cugggguuga ccuuaccaaa      900

gauaacaugg cuuugcagcg ugugcgcgaa gccgcagaga aggcgaaaug ugagcugagu      960

agcucugucc agacagacau uaaucuacca uaccucacca uggauuccuc aggacccaag     1020

caucugaaca ugaaguugac gagagcucag uuugaaggua ucgugacuga ccugauuagg     1080

cggacaaucg ccccuugcca aaaagcaaug caggaugccg agguaagcaa gagugacauc     1140

ggcgaaguua uuuuggucgg gggaaugacc cgaaugccaa aagugcagca aacugugcag     1200

gaucucuucg gccgcgcucc gucuaaggcc gucaaccccg acgaggcagu ggcuauaggu     1260

gccgcgaucc aagggggcgu ucuggccgga gaugugacag acguauuacu gcucgacguc     1320

accccucuuu cccugggcau ugaaacgcuu gggggagugu uuaccaaacu aaucaauaga     1380

aacacaacua uaccaaccaa aaagagccag guuuucucga cagcugcaga uggucagacu     1440

cagguggaga uuaaggucug ucagggcgag agggaaaugg ccggggacaa uaagcugcuc     1500

ggacaguuca cccugaucgg cauucccccu gcuccacggg gugugcccca aaucgaggua     1560

acauuugaua ucgacgccaa cgggauugug cacguuucug caaaagauaa gggcaccgga     1620

cgcgaacagc agauagucau ccaguccuca ggcgggcuua guaaagacga uauugagaau     1680

auggugaaga acgcggaaaa guacgccgag gaggacagaa ggaaaaagga acguguggag     1740

gcugucaaua uggccgaagg aaucauccac gauacugaga cgaaaaugga ggaguucaag     1800

gaccaacugc cggcagauga augcaacaaa uugaaggaag agauuagcaa gaugcgggaa     1860

cuccuggcuc gaaaagacuc cgagacaggu gagaauauaa gacaggccgc aucuagcuua     1920

cagcaggccu cacugaagcu auuugaaaug gcuuauaaaa agauggcgag ugagagggaa     1980

ggcuccggga gcucuggaac cggcgagcaa aaagaagauc agaaggagga gaaacaguga     2040


<210>  465
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  465
auggccgaca aggaggcugg cgggagcgau ggacccagag aaaccgcacc uacauccgcc       60

uacucuucac cagcgaggag ucugggugac acuggcauca cgccgcucag ccccucccac      120

auugugaacg auaccgacuc uaaugucucg gagcagcaau cauuccuugu ugugguagcu      180

guggauuuug ggacaacuag caguggauau gccuacuccu ucaccaaaga accugagugc      240

auacauguca ugcggcgcug ggaaggcggu gacccagggg ugucuaacca gaagacaccc      300

accacuaucc uguugacacc ugagcgaaaa uuucacagcu ucggauaugc agcccgugau      360

uuuuaccaug acuuagaucc aaaugaggcu aagcaguggc uguaucuaga aaaauucaag      420

augaagcucc acaccacggg cgaccugacu auggauaccg accuuacagc agccaacggc      480

aaaaagguua aagcucugga gauuuuugcc uacgcguugc aguauuucaa ggaacaagca      540

cucaaagagc uguccgauca ggccggguca gaguuugaaa auagugacgu gagauggguc      600

aucacugugc ccgcuauuug gaagcagccu gccaagcagu ucaugaggca agcagcuuac      660

caggccggac uggcgagccc agagaacucu gaacagcuca ucauagccuu agagccggaa      720

gcagcuucca ucuacugucg gaaacugcgc cuucaucaga ugauugaguu gucaagcaag      780

gccgcuguaa augguuauag uggcucugac accguugggg ccggauuuac acaagcaaaa      840

gagcacauca gaaggaaccg gcagucccgc accuuccugg uggaaaaugu cauuggcgag      900

aucuggagcg aacuagagga aggugauaag uacguggugg ucgacuccgg gggaggcacg      960

guugaucuca cugugcacca gauacgacug cccgagggcc aucuuaaaga gcuguauaag     1020

gccacagggg gaccuuacgg uucuuugggc guagacuaug aauuugagaa acuccuguac     1080

aagauuuucg gggaagauuu caucgagcaa uuuaagauua aaagaccagc ugcgugggug     1140

gacuuaauga ucgcauucga auccaggaag cgggccgcug cccccgaucg uaccaacccu     1200

cugaauauca cucucccauu uucauucauu gacuauuaca aaaaguuucg cggacacagu     1260

gucgagcaug cacuuagaaa aagcaacgug gauuucguua agugguccuc ucagggcaug     1320

cugaggauga gccccgacgc caugaaugcu uuguuuaagc cgacaauaga uucaaucauu     1380

gagcaccuac gggaccuguu ccagaaaccu gaagugagua ccgucaaguu ucucuuccug     1440

gugggugggu uugccgaggc accccuucug cagcaagcgg uacaggcugc cuucggcgac     1500

cagugccgaa ucauaauucc acaggauguu ggauugacga uccucaaagg cgcagugcug     1560

uuuggguuag acccugccgu caucaaggug cgcagaucgc cccugaccua cggagucggu     1620

gugcuaaaca gguauguuga aggcaaacac ccacccgaga agcuccuggu gaaggauggg     1680

acacgguggu guacugacgu auucgauaaa uucauuagcg cugaccaauc ugucgcccuu     1740

ggagaguugg ugaagcgcuc auacaccccu gcaaaaccaa gucagcuggu uaucgugauu     1800

aauauauaua gcuccgaaca ugauaacguc ucuuuuauca cagacccggg cgugaagaaa     1860

ugcgguacuc ucagacugga ucuuaccggg acaucgggca ccgcuguacc cgccaggcgu     1920

gagauucaga cucugaugca guucggagac acggaaauca aggcgacagc caucgauauu     1980

gcuaccagca aguccgugaa aguuggcaua gacuuuuuga acuacuga                  2028


<210>  466
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  466
augcuggccg ugcccgagau gggccuccag gggcuuuaca ucggaagcuc cccugaaaga       60

ucuccagucc cgucaccccc ugguagucca aggacccaag agagcugcgg cauugcuccc      120

cugacaccuu cccagucucc aaagcccgaa guucgggcac cucagcaggc cucguucuca      180

gugguagugg cgauagacuu ugggacuacg agcaguggau augcuuucuc cuuugccucu      240

gauccagagg caauccacau gaugcgcaaa ugggaaggcg gugacccggg ggucgcccac      300

caaaagaccc ccacauguuu guuacugacu ccugagggag cuuuccacag cuuuggcuac      360

accgcacgag auuauuacca ugaccuagau ccagaggaag cccgugacug gcucuauuuc      420

gagaaauuua agaugaaaau ucacuccgcu acagaucuga cccuuaagac ucagcuggaa      480

gccgugaacg gcaagacaau gcccgcguug gagguuuucg cacaugcccu cagauuuuuc      540

agggagcacg cucugcagga acugcgggag cagucaccua gucucccaga aaaagacacc      600

gugcgcuggg ucuuaacggu gcccgccauc uggaagcaac cggcaaaaca guuuaugaga      660

gaggcugccu accuggcggg gcuuguaagc agggaaaaug ccgagcaguu gcugauugca      720

cuagagccug aagcugccuc uguuuauugc cggaagcucc gccugcacca gcuucuggau      780

uuguccggac gagcucccgg uggcgggaga cucggagaga ggcggucaau cgacagcagu      840

uuccgucaag cccgcgaaca gcugagaagg ucucggcauu cccgaaccuu uuuaguggag      900

agcggcgucg gugaacugug ggcagagaug caggccgggg aucgcuacgu gguggcugac      960

uguggaggcg gcacugucga ucucacaguu caccaacuug agcagccaca ugggacucug     1020

aaagaauugu acaaggcguc gggagguccu uauggcgcag uggggguaga ccuagccuuc     1080

gagcagcugc ucugcagaau auucggagaa gacuuuaucg cuaccuucaa gaggcagcgg     1140

cccgccgcau ggguggaucu gacaauugcc uuugaggcuc gcaaaagaac cgccggccca     1200

cacagggcgg gugcacuuaa caucucucug cccuucuccu uuauugacuu cuaccguaag     1260

caacgggggc acaaugucga aacggcuuug cgaagaucaa gugugaacuu uguuaaaugg     1320

agcucccagg gcaugcucag gaugucuugu gaggccauga augagcuguu ccagccuacu     1380

gugagcggaa ucauacagca uauugaagca uuacuggccc gcccagaggu ccaaggcgug     1440

aagcuacucu uucugguagg gggauucgcu gaaucagccg uucuucagca cgcagugcag     1500

gcugccuugg gugcgcgggg ccugagaguc guggucccgc augauguggg gcucacaauc     1560

cugaaaggag ccguucuuuu uggccaggcu cccggugugg uaaggguccg ccgaaguccu     1620

cugaccuaug gggugggcgu uuugaaccgg uucgugccag gacgucaucc cccugagaag     1680

cuccugguca gagacggcag gcgcuggugc acugaugugu uugagcgguu cguagcagcc     1740

gaacaauccg uggcuuuagg ggaggaaguu agaaggagcu acuguccagc ccgacccgga     1800

cagcgccggg uccugauuaa ucuauauugc ugugcagcgg aggacgccag auucaucaca     1860

gauccgggug ugaggaaaug cggcgcucuc ucucuggaac uugagccugc cgacuguggg     1920

caggauaccg caggagcucc acccggccgu cgcgagaucc gggccgcaau gcaguuuggu     1980

gacacggaaa uuaaggugac cgccgucgau guuucaacaa acagaagugu gagggcuagc     2040

auagacuucu uguccaauug a                                               2061


<210>  467
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  467
auggcccggg agaugaccau ccugggcagc gcugugcuca cacuucuguu ggcaggguac       60

uuagcccagc aauaucugcc ccuaccuacu ccaaagguca uuggaauaga ccucgguacg      120

accuacugcu ccguuggcgu guucuuuccg gggacaggaa aaguaaaggu gauccccgau      180

gaaaacggcc acauuucuau cccuucaaug gucaguuuca cugacaauga uguguauguu      240

gguuacgaga gcguggaacu ggcggacucc aacccacaga auaccauuua ugaugcuaaa      300

agguuuaucg ggaagauauu cacagccgag gaacuugagg cagagaucgg acgguacccc      360

uuuaaagucc ugaacaagaa uggcauggug gaguucucug uaaccucgaa cgaaacuauu      420

acaguuucac cugaauaugu gggcagccgc uugcuccuga agcugaaaga gauggccgag      480

gcuuaccucg ggaugccagu cgcaaaugcc gugaucagug ugcccgcuga auuugacuua      540

aagcagcgaa acuccaccau ugaggccgcg aaucuggcag gacuuaaaau cuugcguguc      600

auaaacgaac cuacggccgc ugccauggca uacggucugc auaaggcuga uguuuuccac      660

gugcuaguaa uugaccucgg cgggggaacu cuggaugugu cucuucugaa uaaacagggc      720

gguauguuuu ugaccagagc caugagcggg aacaauaagc ucggaggcca agacuucaac      780

cagaggcugu uacaguaucu guacaagcag aucuaucaaa cauacggcuu ugucccaucc      840

cggaaagagg aaauucaucg ccucagacag gcgguggaga ugguuaaguu gaaucugacu      900

uugcaccagu cagcccagcu aagugugcug cucaccgucg aggaacaaga uaggaaagag      960

ccgcauagcu cugacacaga acugcccaag gauaaacuuu ccucagcaga cgaccaccgg     1020

gugaacagcg gguucggacg cggucugagu gauaagaaau cuggcgaguc ccagguauug     1080

uuugaaaccg agaucagccg aaaacucuuc gacacgcuga acgaggauuu auuccagaag     1140

auccugguuc cuauucaaca ggugcuaaag gaagggcacc ucgagaagac ugaaauagac     1200

gaggucgugc uggucggagg cucgacaaga aucccaagga uuagacaggu gauccaggaa     1260

uuuuucggua aagaucccaa uaccucuguu gacccugauc uugcuguggu aacugggguc     1320

gccauacaag cuggcauuga cggaggcucc uggccacuuc aggugucagc ccuggagauc     1380

cccaacaagc aucuccagaa aacaaauuuu aacuga                               1416


<210>  468
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  468
auggccgcua ucggcgugca ccuggggugc accagcgcau gugucgccgu uuacaaggac       60

gguagagcgg gagugguagc uaacgaugcc ggcgacaggg ugacacccgc agucguggcc      120

uauuccgaga augaagagau uguugggcuc gcugcaaaac agucucggau acgcaacauc      180

ucaaauacug ugaugaaggu caaacaaauu cuuggacgaa guagcuccga uccucaggcc      240

cagaaguaca ucgcugaauc uaaaugccug gugauugaga agaacggcaa guugcguuau      300

gaaaucgaca cgggugagga gaccaaauuc guaaauccag aagauguugc cagauuaaua      360

uuuucgaaga ugaaagagac agcgcauuca gugcugggga gcgacgcaaa cgaugucgug      420

aucacugugc cguucgacuu uggagaaaag cagaaaaaug cccuaggcga ggcugccagg      480

gcagcuggcu ucaacguccu ccggcugauu cacgagccca gugccgcgcu ucuggccuac      540

gggaucggac aagauucccc uaccgguaag ucuaauauuu ugguuuuuaa gcucggcggg      600

acaagccugu cccugucagu gauggaagua aacaguggaa ucuaucgcgu gcucagcacc      660

aauacugacg auaacauagg cggugcacau uucacagaga ccuuagcuca guaccuggcc      720

ucugaauuuc agagauccuu caaacacgac gucaggggga augcucgggc caugaugaag      780

cugacgaacu cagcagaggu ggccaaacau agcuugagua cucugggauc ugcuaauugu      840

uuucuagauu cccucuauga aggccaggac uucgacugca acguuagccg cgcgcgauuu      900

gagcugcuuu guucgccacu guucaacaag ugcauugagg caaucagagg cuugcucgau      960

caaaaugggu uuaccgccga cgauauuaac aaaguggucc uguguggagg uucuuccagg     1020

auccccaagu uacagcagcu gaucaaagac cucuucccug cuguggaacu ucuuaauuca     1080

auuccacccg augagguaau accuaucggc gccgcaauug aagccgggau cuugauagga     1140

aaggagaacc uacugguuga agacagucuc augauugagu gcagcgcucg ggauauccug     1200

gugaagggcg ucgacgaguc cggugccucu cguuucacag ugcuuuuucc aagcgggacu     1260

ccgcugcccg cacgcagaca gcacaccuug caagcgccug gcucaaucag uuccgucugu     1320

cucgaacugu acgagagcga uggcaaaaau ucugcuaagg aagagacaaa auucgcccag     1380

gugguuuuac aggaccugga uaagaaagaa aacggacuaa gggacauucu cgcagugcug     1440

accaugaagc gggacggguc acuucacgua acgugcacug aucaagagac aggaaagugu     1500

gaggccauca guauugaaau agcuagcuga                                      1530


<210>  469
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  469
augagcgugg ucggccugga cguugggucc cagucuugcu acaucgccgu ggcuagagca       60

ggagguauug agaccauagc caacgaguuc ucagauaggu guacacccag uguaaucagc      120

uuuggcucca agaaucggac uauuggggug gcggcuaaaa accaacagau cacgcacgcc      180

aauaacaccg ucucuaauuu caagcgcuuu cauggacgag cauucaacga cccuuuuauu      240

cagaaagaga aggaaaaucu cucguaugau cuugugccac ugaaaaacgg cgguguuggg      300

aucaagguga uguacauggg agaggaacac uuguucucag ucgagcagau aacagccaug      360

uuacugacua agcuaaaaga gaccgcugaa aauagccuca agaaaccggu gacagacugc      420

guaaucagug uucccuccuu uuucaccgau gcagagcgua gaucugugcu ggacgccgcu      480

caaauugucg gccuuaacug ucugagguug augaaugaua ugacugccgu ggcgcucaac      540

uauggcaucu acaagcagga ccugccuagc cuggaugaaa aaccacggau uguggucuuu      600

guugacaugg ggcauuccgc auuccaggug ucagccugcg cuuuuaauaa gggaaagcuc      660

aaaguauuag guacagccuu cgaucccuuu cugggcggga agaacuucga cgagaaacuu      720

guggagcacu ucugugcaga auuuaagacc aaauauaagu uggaugcuaa aaguaagauc      780

cgcgcccugc uaagacucua ccaggagugc gaaaagcuga aaaagcugau gagcucuaau      840

uccacggacc uuccuuugaa cauagagugu uucaugaacg acaaagaugu cucaggaaag      900

augaauagga gccaauuuga agaacucugc gcggagcugu uacagaaaau ugaagugcca      960

cuguauaguc uccuugagca gacucaucug aagguugaag acgugucugc cgucgagauc     1020

gugggcggug caacccggau ucccgcugua aaggaacgca ucgccaaauu cuuugggaag     1080

gauaucucca caacuuugaa cgcugacgag gccguugcac gaggaugugc ccuacagugc     1140

gcuauucuga gcccugcguu caaagugaga gaguuuucgg ucaccgaugc agugccauuc     1200

ccgauaucuc ucaucuggaa ucacgacucc gaagauacag agggcgucca cgaaguguuu     1260

ucaaggaacc augccgcucc cuucaguaag guucugaccu uucuucggcg uggcccuuuc     1320

gagcuggaag ccuuuuacag cgacccacaa ggggugcccu acccugaggc aaaaauugga     1380

cgcuucguag uccagaaugu guccgcccag aaggauggug agaagucuag aguuaaagug     1440

aaggucaggg ugaacacgca cggcaucuuc acuauaagca cagcuucaau gguagaaaaa     1500

gugccaaccg aggaaaauga gaugaguucc gaggccgaca uggaauguuu gaaccaacgg     1560

cccccggaga auccugauac ugacaagaac guucagcagg acaauagcga agcagggaca     1620

cagccccaag uccagaccga ugcgcagcag acgucucaau caccaccuag ucccgagcuc     1680

accagcgaag agaacaaaau uccagacgcu gauaaggcca augagaagaa aguggaccag     1740

cccccugaag caaagaaacc aaagaucaaa guggucaacg uugagcugcc gaucgaagcc     1800

aauuuagugu ggcagcuggg aaaggaucua cucaacaugu auauugagac agaaggcaaa     1860

augaucaugc aggacaagcu ggagaaggag cgaaacgaug cuaaaaaugc cguggaagag     1920

uacguauaug aauuucgcga caaacuuugc ggucccuacg agaaauucau uugcgaacaa     1980

gaucaucaga acuuuuugag acugcucacu gagaccgagg acuggcugua ugaagagggg     2040

gaagaucagg caaagcaggc uuacgucgac aaacuugagg agcugaugaa gauaggcaca     2100

ccugugaagg uuagguucca agaagccgag gaacggccaa aaauguuuga ggaauuggga     2160

cagcgccucc agcacuaugc gaagaucgcc gcugauuuca gaaauaaaga cgagaaguac     2220

aaccacauug acgaguccga aaugaaaaag guggagaagu cugucaauga agugauggag     2280

uggaugaaca auguuaugaa cgcacaagcc aaaaagucgc uggaucagga ccccguggua     2340

agggcucagg aaaucaaaac uaagaucaaa gaguuaaaua acaccuguga gccugucgug     2400

acacagccaa agcccaagau ugaaagcccg aaacuggagc guaccccuaa uggcccaaac     2460

auagauaaga aagaagagga ccuagaagau aagaauaacu uuggggccga gcccccucau     2520

caaaauggag agugcuaccc caacgaaaag aacuccguga auauggaccu cgauuga        2577


<210>  470
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  470
auggccgaca aggugagaag gcagcggccc cgccgacgug ucugcugggc ucugguugca       60

gugcuccuug ccgaucuguu ggcguuaagc gacacccugg cuguaauguc cguggaucua      120

ggcucugagu caaugaaagu cgccaucgug aagccugggg uuccaaugga aauugugcuc      180

aacaaagaga guagaaggaa gacaccgguc auagugacuc ugaaagaaaa ugagcgguuc      240

uuuggagaca gcgcagccuc cauggcuauc aagaacccca aggcaacgcu ucgcuacuuc      300

caacaccugu uggguaaaca ggccgauaau ccucauguag cucucuauca ggccagauuu      360

ccagaacacg agcugaccuu cgacccccag aggcaaacag uucauuuuca gauuucuucg      420

cagcugcagu ucucaccuga ggaagugcuc ggcauggucu uaaacuacag ccggagucug      480

gcggaggauu uugcagaaca accaaucaag gacgccguga uuacugugcc cgucuucuuu      540

aaucaggcug agcgccgagc cguucuucag gcagcuagaa uggccggguu gaaagugcug      600

cagcuaauca acgauaauac cgcgacagcc cucuccuaug gaguauucag gcggaaggac      660

auaaacacca cugcacaaaa uaucauguuu uacgauaugg gcucugguag cacagugugu      720

accauuguca cguaucagau ggugaaaacu aaggaggcug ggaugcagcc ucaacugcag      780

auccguggag uuggcuucga ccgcacccuu ggcgggcugg aaauggaguu gagacucagg      840

gaacggcugg ccggauuauu uaacgagcag cgaaaggguc agcgcgcuaa agaugugaga      900

gaaaauccaa gggccauggc aaagcugcuc cgggaggcca accgccuuaa aacaguccug      960

uccgcuaaug cggaccacau ggcacaaauu gagggcuuga uggacgaugu ggacuucaag     1020

gccaaaguaa cuagaguuga guucgaggaa cuaugcgcug aucuguuuga gagggugccg     1080

gggcccgucc agcaggcccu ccagucagca gaaaugaguc uggacgagau cgagcaagug     1140

auacuugucg gaggcgccac ccgugugccu cggguucagg aagugcuguu gaaggcugua     1200

gguaaagagg aacucgggaa gaacauuaau gccgaugagg cagcggcuau gggagccguc     1260

uaccaggcag ccgcucugag caaggccuuc aaagugaagc cauuuguugu gcgagacgca     1320

gucguguauc ccaucuuagu agaguucaca agagaggugg aggaagaacc uggcauucau     1380

ucucugaaac acaacaagag gguucuauuu ucccgcaugg gcccauaccc ccagcggaaa     1440

gucaucaccu ucaacagaua cucacacgau uuuaauuucc auaucaacua uggggaccuc     1500

ggauuucugg guccggaaga ucuuagggug uucggcagcc aaaauuugac gacugugaag     1560

cugaaggggg ucggagacag uuuuaaaaag uacccugauu augagucuaa aggcauuaag     1620

gcucacuuca accucgacga guccgguguu cugagccuug accgcgugga aucgguguuu     1680

gagacacugg uagaagauuc ugccgaggaa gaguccaccu ugacuaaacu cgggaauaca     1740

auaucaaguc uguucggcgg aggcaccacg cccgacgcga aggagaacgg gaccgauaca     1800

guccaggaag aggaagagag cccagccgaa ggauccaagg acgagccugg ugaacaggug     1860

gaauuaaaag aggaagcuga ggcacccguu gaagauggcu cucagccacc cccuccagag     1920

ccgaaggggg acgccacucc cgagggagaa aaagcuaccg agaaggaaaa uggcgauaaa     1980

agcgaggccc aaaagccuuc agagaaggca gaagcggguc cagagggggu ggcccccgcu     2040

ccugaaggcg agaaaaagca gaaaccagcc cgaaagcggc guauggucga agagaucgga     2100

guggagcugg uugugcuaga ccuccccgau cugccggaag acaaacuugc acagagugua     2160

caaaaguugc aggaucugac acucagagac cuggagaaac aggaaaggga gaaggcugcc     2220

aacuccuuag aagcauucau uuuugagacu caggauaagc uguaccaacc ugaguaucag     2280

gaagucagca ccgaggaaca gcgcgaggaa aucucuggca aacuuucagc cgcuaguaca     2340

ugguuggagg acgagggggu gggagcgacc acugugaugc ucaaggaaaa acuggccgag     2400

cuacggaagc ugugucaggg ucucuucuuu agagucgaag agaggaaaaa guggccagag     2460

cgacugagcg cacuugacaa uuugcugaac cauuccucua uguucuuaaa gggcgcucgc     2520

cucauacccg aaauggauca aauuuuuacg gagguugaaa ugacaacccu ggagaaagug     2580

aucaaugaaa cuugggccug gaagaacgcc acccuugcug agcaggcaaa acugccugcc     2640

acagagaagc ccguauugcu cucgaaagac aucgaagcga agaugauggc ucuggaucgg     2700

gaggugcagu accuacugaa uaaggccaaa uucaccaagc caagaccuag gcccaaagac     2760

aagaacggga cucgugcaga accaccgcuc aaugccagcg cuuccgauca gggagagaaa     2820

gucauuccuc ccgcaggcca aacagaagac gccgagccaa ucucagagcc cgaaaaggug     2880

gagacgggua gugaaccugg ggauaccgag ccacuggaac uuggcggacc cggcgcggag     2940

ccugagcaga aggaacaguc uacugggcaa aaacgcccgu ugaagaacga cgagcuguga     3000


<210>  471
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  471
augcccgagg aaacccagac acaagaccag ccuauggagg aagaggaagu ggagacuuuc       60

gccuuucagg cugagaucgc acagcugaug agccucauua uaaacacguu cuacuccaau      120

aaggaaaucu uucuuagaga gcugauuucu aacucaagug augccuugga caaaaucagg      180

uaugagagcu uaaccgaucc auccaagcug gacucuggca aagagcuaca cauuaaucuc      240

aucccgaaca agcaagaucg gacacugacu auagucgaca ccgggaucgg aaugacaaaa      300

gcggaucuua uuaauaaccu ggguaccauc gcuaagucgg gcacuaaggc cuucauggag      360

gcauugcagg ccggggcuga cauuucaaug aucggacagu uuggcguugg uuucuacagc      420

gcauaucucg uggccgaaaa aguaacagug auaaccaagc auaaugauga cgagcaguac      480

gcuugggaaa guuccgccgg gggaucuuuu acgguccgca cugauaccgg cgagcccaug      540

ggccgaggga caaaagugau ucugcaccug aaggaagacc aaacugagua ucucgaggaa      600

cguagaauca aagagauugu uaagaagcau agccaguuca ucggauaccc uaucaccuua      660

uuuguggaaa aagagaggga uaaggaaguc uccgacgacg aggcggagga aaaagaggau      720

aaggaagagg aaaaagagaa ggaggaaaaa gagucagaag acaagccaga gauugaggau      780

guggguagug acgaagagga agagaagaaa gauggcgaca agaaaaagaa aaagaagaua      840

aaagaaaagu auaucgauca ggaggagcug aacaaaacaa agcccauuug gacccggaau      900

ccugacgaua ucacgaacga agaguacggg gaguucuaca aaagccuuac uaaugacugg      960

gaagaucacu uggcaguaaa gcauuuuucu guugaaggac agcuggaguu ccgcgcccua     1020

cucuuugugc caagaagggc ucccuucgac cuguucgaga accggaagaa aaagaauaac     1080

auaaaacuuu auguccgccg aguguuuauu auggacaauu gcgaagaacu gaucccugaa     1140

uacuugaacu ucaucagagg cguggucgau uccgaggacc ucccacugaa cauuucaagg     1200

gaaauguuac aacagagcaa gauccugaaa guuauucgga agaaucucgu gaagaaaugu     1260

cuugagcugu uuacagaguu ggccgaagau aaggagaacu auaaaaaguu cuacgaacag     1320

uuuaguaaaa auauaaagcu agguauccac gaggacucuc aaaaccguaa aaagcugucc     1380

gagcuccugc gcuauuacac cagcgcaucg ggggaugaaa ugguaucucu uaaggacuau     1440

ugcacuagaa ugaaagagaa ucagaagcac auuuacuaca ucacaggaga aaccaaagau     1500

cagguggcua acuccgccuu cgucgagagg cugcggaagc auggcuugga agugaucuau     1560

augauugagc cgauagacga guacuguguu cagcaacuca aagaauuuga gggcaagacg     1620

cuggugucag ucaccaagga aggguuagag cugcccgaag augaggagga gaaaaagaaa     1680

caggaagaaa agaaaacaaa guucgagaau cuaugcaaga ucaugaaaga cauucucgaa     1740

aagaaagugg agaagguagu ugugaguaac cgacugguca cuagcccuug uugcaucgug     1800

accuccacau auggauggac ugcgaauaug gagcgcauua ugaaagccca ggcacuuaga     1860

gauaacucua ccauggguua cauggcugcc aagaagcacu uggaaaucaa uccagaccau     1920

agcauaaucg agacacugag gcagaaagcu gaagccgaua agaacgacaa aucagucaag     1980

gaccucguga uucugcuuua ugagaccgca cuguugaguu ccggcuuuag ccucgaggau     2040

ccccaaacuc acgccaaucg gaucuaccgc augauuaaac ugggguuagg aaucgacgaa     2100

gaugacccua cggcugauga cacaucugcg gcaguuaccg aggaaaugcc accccuggag     2160

ggcgaugacg auacuucaag aauggaagag guggacuga                            2199


<210>  472
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  472
auggacagcu ccaagcugga uucuggcaaa gggcuccaca ucaaccuugu gcccaauaag       60

cagaaccaaa cccugacaau ugucgacacu agaauaggaa ugacgaaaac cgauuugauc      120

aauaacuuag guacaguuac uaagucaggc accaaagccu ucauggaggc ucugcaggca      180

gacgccgaua uuaguaugau cgggcauuuu ggagugggcu ucuacagcgc guaucuagua      240

gcuaagaagg ugacagucau uuccaaacac aauaacgacg aacaguacac cugggagucu      300

ucggccggug ggucauuuac ugugaggaca gaugaauga                             339


<210>  473
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  473
augcccgagg aagugcacca uggcgaggaa gaggucgaaa ccuucgccuu ucaggcugag       60

aucgcacaac ugaugagccu cauuauaaac acauucuacu ccaauaagga gaucuuucuu      120

agagaacuga uuucuaacgc cucagacgcg uuggauaaaa ucagguauga gaguuuaacu      180

gacccuagca agcuggauuc cgggaaagaa cuaaagauug acaucauacc aaauccgcag      240

gagcggacgc ucacccuggu ugauacagga aucgguauga cuaaagcuga ccuuauuaac      300

aaucugggca ccaucgccaa gucugggaca aaggcauuca uggaggccuu gcaggcugga      360

gcagauauuu cgaugaucgg ccaguuuggu gugggguucu acucagccua ucucguagcu      420

gaaaaagugg ucgugauaac caagcacaac gacgaugagc aauacgccug ggaaagcagu      480

gcgggaggcu ccuuuacugu ucgcgcagac cauggcgagc ccauugggcg aggaacaaaa      540

gugauccugc accugaagga agaucagacc gaguaucucg aggaacguag agucaaagag      600

gugguaaaga agcauucuca guucauuggu uacccuauca cguuauaucu ggaaaaagag      660

agggaaaagg agaucagcga cgaugaggcc gaagaggaaa aaggcgagaa ggaagaggag      720

gacaaagacg augaagagaa gccaaaaauu gaagacguug gguccgauga ggaggacgau      780

ucaggaaagg acaagaaaaa gaaaacuaag aaaauaaagg aaaaguacau cgaucaggag      840

gaacuuaaua aaaccaagcc cauuuggaca cggaacccug acgauaucac ucaagaggaa      900

uacggcgagu uuuauaaaag uuugaccaau gacugggagg aucaccuggc ugugaagcac      960

uucagcgucg aaggucagcu agaguuucgc gcccuccugu ucauaccaag aagggcaccc     1020

uuugaccuuu ucgaaaacaa aaagaagaaa aauaacauua agcuguacgu gcggcgcgug     1080

uucaucaugg acucuugcga ugaguugauc ccugaauauc ucaauuuuau ucgagggguc     1140

guugacuccg aggaucugcc auuaaacauc ucaagagaga ugcugcagca gagcaaaauu     1200

cucaagguga uaaggaaaaa uaucguaaag aagugucuug aacuguucag ugaguuggcu     1260

gaagacaaag agaacuacaa gaaauuuuau gaagccuucu cuaagaaccu aaaacugggc     1320

auucaugagg auuccacaaa ucggcgucgc cucagcgagc ugcuuagaua ccacaccucg     1380

caaucuggag acgaaaugac gucccuguca gaguauguga guaggaugaa ggaaacucag     1440

aaaagcaucu acuacaucac aggcgagucc aaggagcagg ucgcgaacuc ugccuuugug     1500

gaacggguuc gaaagcgcgg guucgaggug gucuauauga ccgaaccgau ugaugaguac     1560

ugcgugcaac aguugaaaga auuugacgga aagagccucg uaucaguuac uaaagagggu     1620

cuggaguuac ccgaagauga ggaagagaag aaaaagaugg aagagaguaa ggcaaaauuc     1680

gagaaucugu guaagcuaau gaaagaaaua cucgacaaga aaguggagaa ggucacaauc     1740

uccaacagac uggugagcuc uccuugcugu auugucaccu caacguaugg cuggaccgcu     1800

aauauggaaa ggaucaugaa ggcccaggcc cuucgggaua acaguacaau gggguacaug     1860

auggcuaaaa agcauuugga gauuaaucca gaccacccca ucguggaaac ucugcgccag     1920

aaagcagagg ccgauaagaa cgacaaagcu guuaaggacc ucgugguacu gcuuuuugag     1980

accgcgcugu ugagcuccgg auucucucuc gaagauccuc aaacacacuc gaauagaaua     2040

uauaggauga ucaagcuggg cuuagguauu gacgaggaug aagucgcagc cgaggagcca     2100

aacgcugccg ugcccgacga aaucccgccu cuggaggggg augaagacgc aagccguaug     2160

gaggaaguug auuga                                                      2175


<210>  474
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  474
augagagccc ugugggugcu cggccuuugc uguguccugu ugaccuucgg gagcguuagg       60

gcugacgaug agguggacgu agauggaaca guggaagagg acuuagguaa gucccgggaa      120

ggcucucgca cugaugacga ggucgugcag cgagaagagg aggcaaucca acuggauggg      180

cuaaacgccu cacagauucg ugaacucaga gagaaaagug aaaaguuugc guuccaggcu      240

gagguuaaua ggaugaugaa acugauaauc aacagccuuu acaagaauaa agagauuuuu      300

cugcgggaau ugaucuccaa cgccucugac gcacucgaua agauucgccu gaucucgcug      360

acggacgaga augcccucuc aggaaacgaa gaguuaaccg ugaagauaaa augcgauaag      420

gagaaaaauc ugcuucacgu cacagacacu ggcgugggua ugaccagaga ggaguuggua      480

aagaaccugg ggacaaucgc uaaaagcgga accagugagu uccuaaauaa gaugacugaa      540

gcacaggaag auggccaauc cacaucugag cucauuggcc aguuuggggu uggauucuau      600

agcgccuuuc ugguggcuga caaggucauc gugaccucca aacauaacaa ugacacgcag      660

cacauuuggg aaucagauag uaacgaguuc agcgugaucg ccgaccccag ggguaauacu      720

cuuggccggg ggaccacaau aacucugguc uugaaggagg aagcgucuga uuaccucgag      780

cuggacacca uuaaaaacuu aguuaagaaa uauucccagu uuaucaauuu cccuauuuac      840

guguggucaa gcaagacaga aaccguagag gaaccaaugg aggaggaaga ggcagccaaa      900

gaagagaagg aggaaaguga ugacgaggcu gccguggaag aggaagagga ggaaaagaaa      960

ccgaagacga aaaaggucga gaaaacugug ugggauuggg aacugaugaa cgacaucaag     1020

cccaucuggc aacgcccuuc uaaggagguu gaagaggaug aguauaaagc auuuuacaag     1080

uccuucagca aagaaucgga cgauccaaug gcuuauauuc auuuuacagc cgagggagaa     1140

gugaccuuca agucuauacu cuucgucccc acuuccgcgc cucgaggccu uuuugacgag     1200

uacgguagua aaaagucaga cuacaucaag cuguauguga gaaggguauu cauuacagau     1260

gacuuucacg auaugaugcc aaaauacuug aacuucguua aggggguggu cgacagcgau     1320

gaccuacccc ugaauguguc ccgggaaacc cuccagcagc auaaacugcu uaaggucauc     1380

cguaaaaagc uggugcgcaa gacguuggau augauuaaaa agauagccga cgauaaauau     1440

aacgacaccu uuuggaagga guucggaaca aauaucaaac ucggcguuau cgaggaucac     1500

ucuaacagaa cuaggcuggc aaaguuacug cgguuucaga gcucacacca uccuaccgac     1560

auuacaaguc uagaucaaua cguggaacga augaaagaga agcaggacaa gaucuauuuc     1620

auggcuggcu ccagccgcaa agaagccgag ucuucaccau uuguagagag acuccugaag     1680

aaaggguacg aagucauuua ucuuacugag ccgguggacg aauacuguau acaggcuuug     1740

cccgaguucg auggaaagag guuucaaaau guugccaaag aaggugugaa guucgacgag     1800

agugagaaga ccaaagaaag ccgggaggca gucgaaaagg aguuugaacc ucugcucaac     1860

uggaugaaag auaaggcccu gaaagacaag aucgagaagg cugugguauc ccagcgccuu     1920

acagagucuc caugcgcgcu gguggcaucg caguacggcu ggagcgggaa uauggaaaga     1980

auuaugaaag cccaggcuua ucaaaccgga aaggauaucu ccacuaacua cuaugccuca     2040

cagaaaaaga cguucgagau caaucccagg cacccuuuga uucgugacau gcuccggcga     2100

auaaaagaag augaggacga uaagacaguu cuggacuuag cagucgugcu guucgaaacc     2160

gccacucuaa gaaguggcua ccuccugcca gauaccaagg cuuaugguga caggaucgag     2220

cgcaugcuuc gguugucucu gaacauugau cccgacgcca aaguggagga agaaccggaa     2280

gaggagccug aagagacagc agaagacacc acugaggaua cagaacagga cgaggaugag     2340

gaaauggacg ucgggacgga ugaggaagag gaaaccgcga aggagagcac ugcugagaaa     2400

gacgaacucu ga                                                         2412


<210>  475
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  475
auggccagag agcugagggc ucuccuucug uggggccggc gcuugcgacc cuuacugcgu       60

gcuccugccc uagcggcugu gccaggggga aagccgaucc ucugccccag aaggaccaca      120

gcccagcugg guccucggcg caacccagca uggagccuuc aagccggcag acuguucucc      180

acucagacgg cugaagacaa agaggaaccc uugcacucua uuauaucaag uaccgagagc      240

guccaggggu ccacaucuaa gcaugaauuu caggcagaga cuaaaaagcu ccuggauauc      300

guugccaggu cgcuguacuc agagaaagaa guguucauuc gggagcucau cagcaaugcu      360

agugacgccu uagaaaagcu gcgccacaag cuaguauccg auggacaagc guugccugag      420

auggagauuc aucugcagac caacgcagaa aaaggcacaa ucaccauaca ggacacuggu      480

aucgggauga cacaggagga acuugugucu aaucucggaa ccauugcccg aagcggcucc      540

aaggcuuuuc uggaugcccu ucaaaaccag gcagaggcuu caaguaaaau cauuggccag      600

uucggggucg gauuuuauag cgccuucaug guggcggaca gaguugaagu guacucuagg      660

uccgccgcac cagguucacu gggcuaucag ugguugagcg augggagugg agucuuugag      720

aucgcugagg ccucuggcgu gcggacgggu acuaagauaa uuauccaccu caaauccgac      780

uguaaggaau uuagcucgga ggcucgugua cgcgauguug ugaccaagua cucuaauuuu      840

gucuccuucc cccuguauuu aaacgggaga aggaugaaua cacugcaagc cauuuggaug      900

auggacccua aagaugugcg ggaauggcag caugaggaau uuuaccgaua uguggcacag      960

gcccacgaca agccacgcua cacucuccac uacaaaaccg augcuccgcu uaacaucaga     1020

ucaaucuucu auguccccga caugaagccu aguauguuug acguuagcag ggagcuggga     1080

uccucugugg cguuguacag ccggaaagua cuaauucaaa caaaggcaac cgauauacug     1140

ccaaaauggc uccgcuucau cagaggcgug gucgacucag aggauauucc ccugaaucuu     1200

aguagggaac uguugcagga guccgcccuc auccguaagc ugcgggacgu guuacagcag     1260

cgacugauaa aguucuuuau ugaucaaagc aaaaaggacg cugaaaaaua ugccaaguuc     1320

uuugaggauu acggccuauu caugagagaa gggaucguua cggcaacuga gcaggaggug     1380

aaagaagaca ucgccaagcu ccugagguau gagucuucag cacuuccuag uggacaguug     1440

acaagccugu ccgaauacgc cucucgcaug cgggcaggua ccagaaacau uuauuaccuc     1500

ugcgcgccaa auaggcaucu ggcugagcac ucgcccuacu augaggccau gaagaaaaag     1560

gauacugaag uccuuuucug uuucgagcag uuugacgaac ugacauugcu ccaucugcgc     1620

gaguucgaua aaaagaaauu aaucagcgug gaaaccgaca uuguaguuga ccacuacaag     1680

gaggagaagu uugaagaucg auccccggca gccgagugcc ugucagaaaa agagacggaa     1740

gaacuaaugg cuuggaugcg gaacgugcuc ggcagucgug ucaccaaugu gaaggucaca     1800

cugagacuug acacucaccc ugccauggug accguuuugg agaugggggc agcuaggcau     1860

uuccugcgca ugcaacagcu cgccaaaaca caggaggagc gggcgcagcu guuacaaccc     1920

acucuggaaa uaaacccaag acacgcccuu aucaagaaau ugaaucagcu cagggcuucu     1980

gagccuggac uggcacagcu acugguggau cagauuuaug aaaacgccau gaucgcugcc     2040

ggccucguag acgauccccg agcaaugguc ggucgccuga acgagcuuuu ggugaaggcg     2100

cuggagcggc auuga                                                      2115


<210>  476
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  476
augggcaaga ucagcucccu gcccacccaa cucuucaaau gcuguuuuug cgacuuccuu       60

aaggugaaaa ugcacacaau gucuucaagu caucuguuuu acuuggccuu augucugcua      120

acuuucacga gcuccgcuac cgcagggccu gagacacucu gcggagccga acuggucgau      180

gcgcuucagu uuguuugugg ugacagaggc uucuauuuua acaagccaac uggguacgga      240

ucuucgucaa ggcgggcucc gcagaccggc auuguggaug agugcuguuu ccgcagcugc      300

gaccugcgac guuuggaaau guauugugca ccccucaaac cugccaagag ugccagaucc      360

guaagggcuc agcggcacac agauaugcca aagacccaga aagaggugca ucugaagaau      420

gcaucucgcg guagcgccgg gaacaaaaau uacagaaugu ga                         462


<210>  477
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  477
augggcaucc ccaugggaaa gagcaugcug gugcuccuua ccuuccuggc cuuugcuucc       60

ugcuguauug cagccuacag accuucugag acauugugcg ggggugaauu agucgacacu      120

cugcaguucg uuuguggcga uaggggguuu uauuucucac ggccagcgag ucgcgugagc      180

cgacguucca gaggaauagu agaggaaugc uguuuuaggu cuugcgaccu agcucuccug      240

gagacguacu gugccacccc ggcaaaaucg gaacgggaug ugucaacacc cccuacuguc      300

cuuccagaca acuucccccg cuauccugug ggcaaguuuu uccaauacga uaccuggaaa      360

cagagcacac agagacugag gcgggguuug ccagcccucc ugcgcgcucg aagagggcac      420

guucuggcaa aggagcucga ggccuuuagg gaagcuaaac ggcaucgucc cuuaaucgcc      480

cugccuaccc aggacccagc gcacggaggc gcaccgcccg agauggccag uaaucgcaag      540

uga                                                                    543


<210>  478
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  478
augaacagcu ucuccaccuc ugccuuuggc cccguggcuu ucucacuggg gcuccuucug       60

gucuugccug cagccuuucc agcgccgguu cccccuggag aggacaguaa ggauguggcu      120

gccccacaca gacagcccuu aacaagcucc gaaaggaucg acaaacaaau ucgguacaua      180

cuggauggua ucucugcacu acgcaaggag acuugcaaua aaucgaacau gugugaauca      240

agcaaggagg cccucgcuga aaauaaccug aaucuuccua aaauggcaga gaaggacggc      300

ugcuuccaga guggguuuaa cgaggaaacg ugucugguaa agauuaucac cggauugcuc      360

gaguucgaag uguaucugga guaccugcag aaucgauuug aguccucuga agaacaggcc      420

cgugcugucc aaaugagcac aaaagugcuc auucaguucu uacagaagaa agccaagaac      480

cuggaugcga ucacuacccc agaccccaca accaaugcau cccuuuugac uaaacugcag      540

gcccaaaacc aguggcuaca ggauaugaca acccaucuca uacugagauc auuuaaggag      600

uuccuucaga guagccugag ggcuuugcgg caaauguga                             639


<210>  479
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  479
augccccugc ucuggcuuag aggcuuccug uuggccagcu gcuggaucau ugugaggucc       60

ucuccuaccc cagggucaga gggacacagu gcugcaccgg acugucccag cugcgccuua      120

gcggcucugc cuaaggaugu cccaaacucc cagcccgaaa ugguugaggc cgugaaaaag      180

cauauacuaa auaugcucca ccugaaaaag cggccugacg uaacacaacc agugcccaaa      240

gcagcccuuc ugaacgcuau ccgcaaguug caugucggua aggugggcga aaauggguac      300

guugagauug aagaugacau cggacgacgu gcagagauga acgagcucau ggaacagacu      360

ucugagauua ucacguuugc cgaaucgggc accgcuagaa aaacacugca cuucgagaua      420

ucaaaggagg guagcgaucu gagugugguc gaaagggccg agguguggcu cuuuuuaaaa      480

guaccuaagg cgaaucggac ucgcaccaaa guuacaauca gacuguucca gcagcaaaag      540

cauccacagg ggucccuuga caccggagaa gaggcagaag aggugggcuu gaagggcgag      600

aggucugaac ugcuacucag cgagaaaguc guggaugccc ggaaguccac uuggcacgug      660

uuuccggucu caaguagcau ucagcgccug cuugaccagg ggaaaucuuc ccuggauguu      720

cgaaucgcuu gugaacaaug ccaggaguca ggagccagcu uggugcuccu ggguaagaaa      780

aagaaaaagg aagaggaggg cgaagggaag aaaaagggag gcggugaagg gggagcaggc      840

gcugacgagg agaaagaaca gagucacaga cccuucuuaa ugcugcaggc caggcaaucu      900

gaggaucauc cucaccggcg ucgcagaagg ggccucgagu gugacgggaa gguaaacauu      960

ugcuguaaaa agcaguuuuu cguguccuuu aaggauaucg gauggaauga cuggauaauu     1020

gcgccaagcg guuaucaugc caacuacugc gaaggcgagu gucccucgca caucgcaggg     1080

acaucuggau ccucacuuag uuuccacagc accgucauua aucauuaucg gaugcgaggc     1140

cacuccccuu uugcuaaccu gaaaucuugc ugugugccaa cgaaguugcg ccccaugagc     1200

augcuauacu augacgaugg ucagaauauc aucaaaaagg acauucaaaa caugauaguu     1260

gaagagugcg ggugcucaug a                                               1281


<210>  480
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  480
auggacggcc ugcccgggag agcccucgga gcugcaugcc uucuguuguu agccgcgggu       60

uggcugggcc cugaggcuug ggggagccca accccgcccc cuacaccagc cgcacccccu      120

ccacccccuc caccgggauc ccccggcggu ucucaggaua cuuguacguc augcggggga      180

uucaggcggc cugaggaacu aggccgcgug gacggcgauu uucucgaagc cgucaagcga      240

cacauccuga gucgucuuca aaugagaggg aggccaaaca uuacccaugc uguucccaaa      300

gcagccaugg ugacagcucu gcggaaguug cacgccggaa aaguacgcga ggacgguaga      360

guggaaauac cucaucucga uggccacgcg agcccagggg cagacggaca ggagaggguc      420

uccgagauca uuucuuucgc cgaaacugau ggccuggcuu cgucacgggu gcgccuguac      480

uuuuucauca gcaaugaggg uaaccagaau cucuuuguug ugcaggccag uuuauggcug      540

uaucuuaagu ugcugcccua cguccuagaa aaaggguccc gaagaaaggu gaggguaaag      600

guuuauuucc aagagcaggg acauggcgac cgguggaaca ugguggagaa acgugucgau      660

cucaagcgcu cuggcuggca caccuuuccg cugacagaag caauucaggc ucuuuucgag      720

agaggggaaa ggcggcugaa uuuggacgug cagugugaua gcugccaaga gcucgccgug      780

gucccuguuu uuguggaccc cggagaagag ucccaccgac cauucguagu gguccaggcg      840

cgccugggug auucaagaca uaggauccgg aaacgcggcu uagaguguga cgggagaacc      900

aaccugugcu guaggcagca guuuuucaua gacuuucguc ucaucggaug gaaugauugg      960

auuaucgccc cuacuggcua cuaugguaac uacugcgaag ggaguugucc cgcauaucuu     1020

gcuggcgugc caggaagcgc cucuuccuuc cacacagcug uugugaauca auaccggaug     1080

cgaggccuga accccgggac cgucaauuca ugcuguauuc cuacgaaguu gagcacuaug     1140

aguaugcuau acuucgacga ugaguauaac aucgugaaaa gagacguacc aaauaugaua     1200

guugaagagu gcggaugcgc cuga                                            1224


<210>  481
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  481
auggcccuga gagugcuccu ucugaccgcu uugacauuau gccacggcuu caaccuggac       60

acugagaaug caaugacguu ucaggaaaac gccagggggu ucggacaaag cgucguucag      120

cuacaggguu cccggguggu agugggcgcg ccccaggaga ucgucgcugc caaucaacgc      180

gggucucucu accaguguga uuauucaacc ggaaguugcg aaccuauucg acugcaagug      240

ccaguugagg cagugaacau gagccuuggc cuguccuugg ccgcuacaac uucuccgccc      300

cagcuccugg cauguggucc uaccguccau caaacaugcu cggaaaauac cuacgugaag      360

gggcuguguu uucucuucgg aucaaacuua cgucagcagc cacagaaauu ucccgaggcc      420

cugagaggcu gcccucaaga ggacagcgau auagcuuucc uuaucgacgg cagugggucc      480

auuaucccac acgauuuuag gcggaugaag gaguucguau cuacuguuau ggaacaguug      540

aaaaagagca aaacacuguu uucccuaaug caguauucag aagaguuccg cauucauuuu      600

accuucaagg aguuucaaaa uaaccccaau ccuagaaguc ucgugaagcc aaucacgcag      660

cugcuuggaa ggacucacac cgccacaggu auacggaaag ucgugcgcga acuguucaac      720

aucacuaaug gcgcgcgaaa gaacgcauuc aaaauuuugg uggucaucac cgacggggag      780

aaguuuggag auccgcucgg cuacgaagac guuauucccg aggccgauag agaaggugug      840

aucagguaug uaauaggggu gggagacgcu uuccggagcg agaaaucucg ucaggagcug      900

aauacaauug ccuccaagcc uccacgcgau caugucuuuc aggugaacaa uuucgaagca      960

uuaaagacca uccaaaacca gcugagagag aaaauuuuug cuaucgaagg cacgcagacu     1020

ggcucaagca guucuuucga gcacgaaaug ucccaggagg gguuuagcgc cgcgaucaca     1080

ucgaacggac cccuccuuuc uaccguuggu uccuacgacu gggccggcgg gguguuccug     1140

uauacuucaa aggagaaaag uacauuuauu aauaugacca gggucgauag cgacaugaac     1200

gacgcauacu ugggauacgc ugccgcuaua auccuacgga aucgagugca aucccuggua     1260

cucggcgccc cucgcuauca gcacauuggu cugguugcaa uguucagaca gaacacgggg     1320

augugggaau cuaaugccaa cgugaagggc acccagaucg gagcuuacuu uggcgcgagc     1380

cuuuguucag ucgaugugga caguaauggg uccacagauc uggucuugau aggagcacca     1440

cauuauuacg agcaaacuag ggguggccag gugagcguuu gcccccuccc gcgggggcgc     1500

gccagauggc agugugacgc ugugcuguau ggagaacagg gccaaccuug ggguagguuc     1560

ggggccgcau uaaccguacu gggcgauguc aacggagaca aacuaacaga uguggccauu     1620

ggcgcucccg gggaggaaga caaucgugga gccguuuacc ucuuucacgg uacuucuggc     1680

ucagggauca guccaagcca uucccagcgg aucgcaggau cuaagcuguc gccucgacuu     1740

caguauuucg gccagagcuu guccgguggg caggaucuga ccauggacgg ccucguggau     1800

cugacagucg gagcgcaggg ccacgugcuu cuguugagau cacagcccgu acucagggug     1860

aaagcuauua uggaguucaa cccacgcgag guugcccgga augucuuuga augcaacgac     1920

caagugguga aggggaagga ggcaggagaa gucagaguuu gucugcacgu gcagaaaagu     1980

accagggacc gcuuacgaga gggccagauc cagucugugg uaacuuacga ucuggcccua     2040

gacagcgguc ggccccauuc ccgugcuguc uucaaugaga cgaagaacuc aacaagaagg     2100

caaacccagg ugcucgggcu gacucagacc ugcgaaacac uuaaauugca gcugccuaau     2160

ugcauugagg auccaguuag cccgauagug cuccgccuga acuuuucuuu agucggaacc     2220

ccucuguccg ccuucggcaa ccuucggccu guguuggcag aagacgcuca aagacucuuu     2280

acugcccugu ucccauuuga gaagaauugu gguaacgaua auaucugcca ggacgaucua     2340

aguauuacau ucagcuuuau gucucuggac ugucucguug ugggcgggcc cagggaguuc     2400

aacguaacgg ucaccgugcg aaaugaugga gaagacuccu accgcacuca ggugacauuu     2460

uucuuuccuc uggaucuuuc auaucggaaa gucaguaccu ugcaaaacca gagaagccag     2520

aggucguggc gucuggcgug cgaguccgcc ucuagcacag aaguuucagg cgcuuuaaag     2580

aguacuuccu guucuaucaa ucacccaauc uuccccgaga acagcgaagu gaccuucaau     2640

auuacguuug acguagauuc caaggcauca cucgggaaca aacugcuucu gaaggccaau     2700

gugaccagcg agaacaauau gccgcgcaca aacaaaacug aguuccaguu ggaacucccu     2760

gucaaguacg cuguguauau gguugugacc agucauggag ucucuacaaa auaccugaau     2820

uuuacugccu ccgagaacac cagccgggug augcaacacc aguaucaggu uucgaaccua     2880

ggccagagau cacugccaau aucucucgug uuccuggucc ccguaaggcu uaaucaaacg     2940

gugaucuggg accgaccuca gguuacauuu agugaaaacu uguccucuac cugccauacu     3000

aaggagcggc ugcccagcca cagcgacuuc uuagcagaac uccgcaaggc gccagugguc     3060

aauuguucca uugccgugug ccagagaauc cagugugaua uucccuuuuu cgguauccaa     3120

gaggaauuua acgcuacacu gaaagggaau cuuucauucg acugguacau aaagaccagu     3180

cacaaccauc ugcuaaucgu aagcacugcc gagauucucu uuaaugauuc uguguucacc     3240

cuguugcccg gacagggcgc auucgucagg ucccagacag agacgaaagu ugaaccauuu     3300

gaggugccga acccucugcc cuuaaucgug gguucaagug ucggcgggcu ccugcuucug     3360

gcuuugauua ccgccgcacu cuauaagcug ggauucuuua aacggcagua caaggacaug     3420

augagcgaag gcgggccacc cggagccgag ccucaauga                            3459


<210>  482
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  482
auguucagcc ugaagacccu ccccuuucuu cuguuguuac acgugcagau cuccaaagcc       60

uucccugucu cuucaaagga gaaaaacaca aagacuguuc aagacuaccu ggaaaaauuu      120

uaucagcuac caaguaauca guaccagagc acgagaaaga acggcaccaa ugugauugua      180

gagaagcuca aagaaaugca aagguucuuu gggcugaacg ugacaggaaa gccgaaugag      240

gaaacucuug auaugaugaa aaagccccgg ugcggugucc cugacuccgg cggguucaug      300

cugaccccag gaaaccccaa augggagcgc acaaauuuga ccuaucgaau acguaacuac      360

acuccucagc ucucugaggc ugaaguggag agagcaauca aggaugccuu ugaacugugg      420

ucgguugcgu caccacugau uuucacaagg aucagccagg gcgaggcuga cauuaauauc      480

gccuuuuauc agcgggauca uggugacaac agucccuucg augggccuaa uggaauacuc      540

gcacacgccu uucaaccagg ccagggcauc gggggagacg cucauuucga ugcagaggaa      600

accuggacga acacuuccgc caauuacaac uuauuucugg uggcugccca cgaguucggu      660

cauucucuug gcuuggcgca cagcuccgac ccgggggcac ugauguaucc caauuacgcc      720

uuccgcgaaa ccucaaacua cagucuaccu caggaugaca uugauggaau ccaggcuauu      780

uauggccuca gcucuaaccc aauccaaccc acagguccuu ccacuccaaa gcccugugac      840

ccgucacuga ccuuugacgc cauaacaacc cuuagagggg agauucuguu cuuuaaagau      900

agguacuucu ggcggcgcca cccucaguug cagcgagucg aaaugaauuu uaucagccuc      960

uucuggccca gucugccaac gggcauucaa gcagcuuaug aggacuuuga uagagacuua     1020

aucuuccugu uuaagggaaa ccaguacugg gcccucucug gcuaugauau ccuucagggg     1080

uacccuaaag acauuuccaa uuauggauuc cccagcucgg ugcaggcgau agaugccgca     1140

guauuuuaca ggucuaagac uuacuucuuu guuaacgacc aauucuggcg guaugauaau     1200

cagcgucagu ucauggagcc agguuacccc aaauccaucu caggcgcuuu uccugggauu     1260

gaaaguaagg uggacgccgu cuuccagcaa gagcacuuuu uccauguguu uagcggacca     1320

cgcuauuacg cuuucgaucu gaucgcccag agagugacaa gggucgcacg gggcaacaaa     1380

ugguugaauu gccgauaugg uuga                                            1404


<210>  483
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  483
augagccugu ggcagccccu cgugcuuguc cuguugguuu uaggcugcug uuucgccgcu       60

ccuagacaaa ggcaguccac ccuggugcua uuuccagggg accuccggac aaaccugacu      120

gaucgccagc uugcagagga auaccuguau cgauacggau auacgcgugu agccgagaug      180

agaggugaau cuaaaucauu gggcccggcg cuccugcugc uccagaaaca auuaagucug      240

cccgagaccg gggaacuuga cagcgcuaca uugaaggcca ugaggacucc ucggugcgga      300

gugccagauc ugggccgcuu ccagaccuuu gagggugacc uaaaauggca ccaucacaau      360

aucacauacu ggauucagaa cuauuccgag gaucucccca gagcagucau agacgaugcc      420

uucgcuaggg cauuugcccu guggucugcu gugaccccuc uuacuuucac acggguuuac      480

ucgcgcgacg ccgauaucgu gauucaguuu ggggucgcgg aacauggaga cggcuaucca      540

uucgauggca aggacgggcu guuggcacac gccuuucccc cuggaccagg uauccaaggc      600

gaugcucauu ucgacgacga ugagcucugg ucacugggga aaggaguggu aguuccgacc      660

cgauuuggca augccgacgg ugcagcuugu cacuuccccu uuauuuucga agggagaagc      720

uacagugccu gcacgacuga uggaaggucc gacggcuuac cuugguguuc uaccacagcg      780

aacuacgaua cugacgaucg guucggcuuu ugcccaagcg agcgucugua uacccaggac      840

gggaaugccg auggaaagcc cugucaguuc ccuuuuaucu uccaggguca auccuacuca      900

gcaugcacaa ccgacggccg cagugauggg uauagauggu gugcuacgac ugccaacuac      960

gacagggaca agcucuuugg auucugccca acacgggcug auagcaccgu gaugggcggu     1020

aauucugccg gggagcuuug ugucuuuccc uucacuuuuc ugggcaaaga auauuccaca     1080

ugcaccucag agggacgagg cgacgggcgc uuguggugcg caacgaccag caacuucgau     1140

agugacaaga aauggggauu uuguccggau caggguuacu cucuauuccu gguggccgcu     1200

cacgaauuug gccaugcgcu cgggcuggac cacuccagcg ugccugaggc acuuauguau     1260

cccauguaca gauucacaga aggaccaccu cugcauaagg augacgucaa uggcauaagg     1320

cacuuguacg guccccggcc agagcccgag ccucgcccac cgacuaccac aacuccccag     1380

ccuaccgccc cacccacagu uugcccuacc gggccaccca cugugcaccc gucggaaaga     1440

ccuacggcug gcccaacagg acccccuucu gccggcccca ccgggccacc uacugcagga     1500

cccuccaccg ccacaaccgu accacucuca ccgguggaug acgcuuguaa cgucaauauc     1560

uucgaugcca uugcagagau cgguaaccaa cuguauuuau uuaaagacgg caaguacugg     1620

agguucagug aagggcgugg aagccggccu cagggccccu uucugauugc ggauaagugg     1680

ccagcucuac cccgaaaacu cgacuccgug uucgaggaaa gacugucuaa gaaauuguuu     1740

uucuuuagcg guaggcaggu uuggguguau acuggggccu caguccuugg cccucgccgg     1800

cuggacaagc ucggacuggg cgcagaugug gcccagguaa caggggcucu uagaagugga     1860

aggggcaaaa ugcuguuguu cuccggucgc cgacucuggc gguuugacgu uaaggcccaa     1920

augguggauc cacguagcgc aucugagguc gacagaaugu uccccggggu gccucuggau     1980

acgcaugacg ucuuucagua cagggagaag gcuuauuucu gccaggaucg cuuuuacugg     2040

cgggugucaa guagaagcga auuaaaucag guugaccaag ugggauaugu aaccuacgau     2100

auccugcagu guccggagga cuga                                            2124


<210>  484
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  484
augcaccccg gcgugcuggc cgcuuuccuc uuucuuagcu ggacccauug cagagcacug       60

ccuuugccau ccgggggaga cgaggaugac uuaucugaag aggaucugca guucgccgaa      120

agguaccuac ggucauauua ccacccgaca aaccucgcgg guauccugaa ggagaaugcu      180

gccaguagca ugacugaacg ccuucgagag augcaauccu uuuucggccu ggaggucacg      240

gggaaauugg acgauaacac ccucgacguu augaagaaac cccguugugg agugccugau      300

guaggcgaau auaauguguu uccaagaaca cugaaguggu cuaaaaugaa ccugacuuac      360

aggauuguca auuauacccc cgacaugaca cauucggagg uggaaaaggc auucaagaaa      420

gccuuuaagg uuuggucaga ugugaccccu cucaacuuca cucgguuaca cgacgguaua      480

gcugauauca ugauuagcuu ugggaucaaa gagcauggag acuucuaccc auuugauggc      540

cccaguggcc ugcuugcaca cgccuucccu ccagggccga auuauggagg ugacgcucac      600

uuugacgaug acgagacaug gaccuccucu agcaagggcu acaacuuguu ccuggucgcc      660

gcgcaugagu ucgggcacuc ccuaggacuc gaucauucaa aagaccccgg cgcacugaug      720

uuuccuauuu acacguauac ugguaagagu cacuucaugc uuccagauga cgaugugcag      780

gggauccaga gccuguacgg acccggcgac gaagauccua auccaaagca ccccaaaacc      840

ccggacaagu gcgauccuuc uuugucccuc gacgccauaa caucacugcg cggcgaaacu      900

augaucuuua aagacagauu cuuuuggagg uuacaucccc agcaaguaga ugcugagcug      960

uuccucacca agagcuuuug gccagaacuu ccuaaccgga uugacgccgc auaugagcac     1020

cccagucaug aucugaucuu cauuuuucgc gggcgaaaau ucugggcuuu gaauggauac     1080

gacauccuag aggguuaucc aaagaaaaua ucugaacugg gccuccccaa ggagguuaag     1140

aaaauuuccg ccgcggugca cuuugaagau acagggaaga cccugcuuuu cagcggaaac     1200

caggucugga gauacgacga uacgaaucau aucauggaca aagauuaucc uaggcugauu     1260

gaggaagacu uuccaggcau cggugauaag guggacgccg uguacgagaa aaacggguac     1320

aucuauuucu ucaauggccc gauucaguuu gaguacucga uauggucuaa ccggaucguc     1380

cguguuaugc ccgcaaacuc cauuuugugg uguuga                               1416


<210>  485
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  485
auggagaccc ccaacacaac ugaagacuac gauacgacca cagaguucga cuauggcgau       60

gccacuccuu gccagaaggu gaaugaaaga gcuuuugggg cacaacugcu cccaccgcuu      120

uacagccugg ucuucguuau cggauuggug gguaacauuu uaguagugcu gguccuagug      180

caguauaaaa ggcucaagaa uaugaccucc auauaccugc uuaaccuggc caucucugac      240

uugcucuuuc uguucacacu gcccuuuugg auugauuaua aacucaagga cgauuggguu      300

uucggcgacg cgauguguaa aaucuuauca ggguuuuacu auaccggacu guacagugag      360

auuuucuuua ucauacuuuu gacuaucgau cgguaccugg cuauugugca cgccgucuuc      420

gcacuacgcg cccgaacagu gaccuuuggc guaaucacga gcauuaucau augggcucuc      480

gcaauucugg ccuccaugcc uggucuuuau uucucuaaga cucaguggga auuuacccau      540

cacacaugcu cgcugcauuu cccacacgag ucauugcgug aguggaaacu cuuccaggcu      600

cugaaguuaa aucuguuugg gcucguucuu ccccuguugg ugaugaucau uuguuacacu      660

ggaaucauca agauucuacu gagaaggccu aacgagaaaa agagcaaagc cguccggcuc      720

auauucguga ucaugauuau cuuuuuccug uuuuggaccc cauauaaucu uacaauacug      780

auuagugugu uccaagacuu uuuguucacc caugaaugcg aacagucccg ccaccucgau      840

cuggcggucc agguuacgga ggugaucgca uacacucacu guugcguaaa ccccgugauc      900

uaugccuuug ucggcgagag auucaggaag uacuuacggc agcuguuuca ucgccgagug      960

gcuguucacc uagugaagug gcucccuuuc cugucugucg acagacuuga aagggugagc     1020

uccacaucac caaguaccgg cgagcaugaa uugagcgccg gguuuuga                  1068


<210>  486
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  486
augagaaccc uggccugccu ccuucuguug ggaugugggu acuuagcuca cgugcuggca       60

gaggaagccg agauccccag ggaagucauu gagcggcuag cgcgcagcca gauacauucc      120

auccgagacc uccaacgucu gcuugaaauu gauucuguug gaucagagga cagucuggau      180

acuagcuuga gagcucacgg ugugcaugcc acaaagcacg uaccugagaa aaggccacuc      240

ccgauccggc gcaagagauc cauugaagag gcagugcccg ccgucugcaa aacgaggacc      300

gugaucuaug aaauaccucg gucucagguu gacccaacau cggcuaacuu ccugaucugg      360

cccccuugug uggaggucaa gcgcugcacu ggcuguugca auaccucaag cgugaaaugu      420

cagccaaguc gaguacauca cagauccguu aagguggcaa aggucgagua cgugaggaaa      480

aagcccaaac ugaaggaagu gcagguccgg cucgaggaac acuuagagug cgccugugcu      540

acaaccucuc ugaacccuga uuaucgugaa gaggacacug ggcgcccaag agagagcggc      600

aaaaagagga agcggaaacg acuuaagccg acauga                                636


<210>  487
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  487
augaacagau gcugggcccu guuccucagc cuuuguugcu accugagguu gguguccgcu       60

gagggcgacc ccaucccuga agaguuauau gaaaugcugu cugaucacuc aauucggagu      120

uuugacgauc uacagcgccu ccugcauggg gacccaggag aggaagaugg ugcagagcuu      180

gaccugaaua ugacccgaag ccacuccggc ggggaguugg aaucucucgc ccguggaaga      240

aggucgcugg gcucacugac aauagcggag ccggcuauga ucgccgaaug uaagacucgg      300

acggaggucu ucgagauuag ccgcagacuc aucgauagga ccaacgcaaa cuuuuuaguu      360

uggcccccuu gcguggaagu acaacggugu agugguugcu guaauaaucg caacgugcag      420

ugccgaccaa cacaggucca gcugagaccc gugcaaguua ggaaaauuga gaucgugcgg      480

aagaaaccua uauucaagaa agccacuguc acccuugaag accauuuggc uuguaagugc      540

gagacagugg cagccgcucg uccaguaacc cgcucccccg ggggaucuca ggaacagaga      600

gccaagacuc cucagacaag gguuaccauc cggacggugc gaguccgcag accaccgaaa      660

ggcaagcaca ggaaauuuaa gcauacucac gauaaaaccg cgcugaagga gacacuaggc      720

gcauga                                                                 726


<210>  488
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  488
augagccugu ucggccuccu ucuguugacc uccgccuuag cugggcagag acaaggaaca       60

caggcagagu cuaaccuguc aaguaaguuu caguucagcu ccaauaaaga acagaacggu      120

gugcaagacc cccagcacga gaggaucauu acugucucua cgaauggcuc gauacauuca      180

ccucgguuuc cacacaccua cccgcgcaac acaguucuag uguggcgacu cguagccgug      240

gaagagaaug ucuggaucca gcugacuuuc gaugaacguu uugggcuuga ggaccccgag      300

gaugacauuu gcaaguauga uuucguggaa guugaggaac cuagcgacgg aaccauccug      360

ggcagauggu gugguagugg gacagugcca ggaaaacaga uuuccaaggg caaccaaauc      420

aggauacggu uugucucuga ugaguacuuc cccagcgagc cuggcuuuug cauccauuau      480

aauauuguga ugccacaguu caccgaagcg guaucccccu caguuuugcc uccaagugcu      540

cucccgcugg accugcucaa caaugccauc acugcauuua gcacauuaga ggaucugauu      600

cgcuaccuug aacccgagag auggcaguug gaccuggaag aucuauauag gccuaccugg      660

cagcuccugg ggaaagccuu cguguuugga cggaagucuc gcgucgugga ccuuaaccug      720

uugacggagg aggugcgacu cuacuccugu acuccaagaa auuucucagu cagcaucagg      780

gaggaacuga agcggaccga uacaauauuc uggcccgguu gcuuacuggu uaaacguugu      840

ggcgggaacu gcgcuuguug ccuccacaau uguaacgaau gccaaugugu gccuaguaag      900

guaacuaaaa aguaucauga ggugcuucag cugcgcccaa aaaccggagu cagaggcuug      960

cacaagucuc uaacagacgu ggcacuggaa caccaugagg agugcgacug cguuuguagg     1020

gguuccaccg ggggauga                                                   1038


<210>  489
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  489
augcacagac ugaucuucgu guacacccuc auuugcgcca acuuuuguag cugcagggac       60

acauccgcua cuccccaguc ugcaucaaua aaggcccuuc ggaaugcgaa ccugcgccga      120

gaugacuugu aucguagaga ugagacgauc caagucaaag gaaaugggua cguucagagu      180

ccuagguucc caaacagcua uccgcggaau uuacugcuaa ccuggcgccu ccauucccag      240

gaaaacacaa ggauucagcu gguguuugac aaucaauucg gacuugagga agcugagaac      300

gauaucugua gauacgacuu uguagaagug gaggauauuu cugagacuuc gaccaucaua      360

cggggucgcu ggugcggcca caaggaagug cccccucgaa ucaaaucaag aacaaaucag      420

auuaagauca ccuucaaaag cgacgauuau uuugucgcca agccaggguu caagauuuac      480

uauagucugu uggaggacuu ucagcccgca gccgcuuccg aaacuaacug ggagucuguu      540

acaagcucca ucucaggagu gaguuacaau agcccuucug ucaccgaucc aacgcucaua      600

gcagacgccc uggauaaaaa gauugcugag uucgacacug uggaagaccu gcucaaauac      660

uuuaaccccg aguccuggca ggaagauuua gagaauaugu aucuggacac cccuagguac      720

cggggccguu cauaucauga ucgcaagagc aaaguagacc uugauagauu gaacgacgau      780

gccaagaggu acaguuguac accacggaau uauucuguua acauccgaga ggaacugaag      840

cuagcgaacg uggucuucuu uccgcgcugc cuccuggugc aaagaugugg ugggaauugc      900

ggauguggca cugugaacug gagguccugc accuguaaua gcggcaaaac agucaagaaa      960

uaccacgagg uucuucaguu cgaacccggg cauauuaagc ggcgcggcag agcaaaaacc     1020

auggcccugg uggacaucca guuggaucac cacgagaggu gcgacugcau cuguucgucu     1080

cguccuccac gguga                                                      1095


<210>  490
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  490
auggugaccc acagcaaguu ccccgccgcu ggcaugucca gaccucugga cacaucucuc       60

aggcuuaaaa cuuuuucaag uaagagcgag uaccagcugg ucguuaacgc agugcggaaa      120

uugcaagaau ccggguucua uuggucugcc guaacgggag gugaggcgaa uuuacugcua      180

ucggcugaac cagccggcac cuuucucauc cgcgauucaa gcgaccagcg acauuucuuu      240

acacugagug ugaagacuca guccgggacc aaaaaccuuc guauucagug cgagggaggc      300

ucuuucagcc ugcaauccga uccgagauca acacagcccg ucccuagguu ugacugugug      360

uugaagcucg uucaccauua caugccaccc ccuggugcac caaguuuccc cagcccucca      420

accgaaccgu cuuccgaggu gcccgagcag ccuucagccc agccacugcc cgggagcccu      480

ccacggcgcg cuuauuacau auauagugga ggcgaaaaga ucccccuggu ccucucuaga      540

ccguuaucca gcaauguggc aacucugcaa caccuuugca ggaaaacagu aaacggccau      600

uuggauucgu acgagaaggu uacccagcug ccugggccca uucgggaauu ucuagaccag      660

uaugaugccc cacucuga                                                    678


<210>  491
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  491
auggugccca gcgccggcca gcuggcucuc uucgcacuug ggaucguccu ggccgcgugc       60

caggcuuugg agaacuccac cucuccuuua ucagccgacc caccgguugc agccgcugug      120

guaagucacu uuaaugauug ucccgacagc cauacacaau ucugcuuuca cggaacuugu      180

agauuccugg ugcaggaaga uaagccugca ugcgucuguc auuccgguua cgugggcgcc      240

aggugcgagc acgcugaccu acucgccguu guggcggcau cucagaaaaa gcaagccauu      300

acggcucugg ucgugguauc gauaguugcc cuugcagugc ugaucauuac cugugucuug      360

auccauugcu gucaggugcg gaaacacugc gaaugguguc gcgcucucau uugccgacac      420

gagaagccau cagcccugcu gaaagggcgu acagcgugcu gucauagcga aacugugguc      480

uga                                                                    483


<210>  492
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  492
augcccccua gcggccugag acuccuucca cuguuguuac cgcugcuaug gcuccuggug       60

cuuacccccg ggaggccugc cgcuggacug uccacaugca agacuaucga cauggaguug      120

gucaaacgga agcgcauuga agcaauacga ggucagaucc ucucuaaacu gcgucuggcc      180

ucaccaccca gucaaggcga gguuccucca gggccccucc cugaagcggu guuagcucug      240

uacaacagca cgagagauag gguagccgga gaguccgcag aaccagagcc ggagcccgaa      300

gccgacuauu acgcuaagga ggugacccgg guccuuaugg uggaaacaca caaugagauu      360

uaugauaaau ucaagcaguc uacucauucg aucuacaugu uuuucaacac cucagaguug      420

cgcgaagcag uuccugagcc agugcugcua agcagagccg aacucaggcu gcuucggcug      480

aaguugaaag ucgagcagca cguggaacuc uaucagaagu acaguaauaa cuccuggcgc      540

uaucugucua aucgauuacu ggcucccagc gacuccccug aguggcucuc auuugaugua      600

acaggcguug ugagacaaug gcuuaguagg gguggggaga uugaaggauu ccggcugagc      660

gcccauuguu cuugcgacuc ccgugauaac accuugcagg ucgacaucaa uggcuuuacu      720

acaggccgca gaggggaucu agcgaccaua cacggaauga acaggccauu ccugcuccug      780

auggcaacgc cccuugagcg ggcccagcau cugcagucaa gccgacaccg cagagcuuug      840

gacacuaauu acuguuuuag uucuaccgag aaaaacugcu gugugaggca acucuacauc      900

gauuuccgga aggaccuggg uuggaaaugg auucacgaac cgaagggcua ucaugccaau      960

uuuugcuuag ggccuugucc cuacaucugg ucccuggaua cacaguauag caaggugcua     1020

gcacucuaca accagcacaa uccaggagcu ucggccgcgc cuugcugugu cccccaggcc     1080

cuggaaccac uucccauugu uuauuacgug ggccgcaaac cuaagguaga gcaauugucu     1140

aacaugaucg ugagauccug caaauguuca uga                                  1173


<210>  493
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  493
augcacuacu gcgugcugag cgccuuccuc auccuucauc uggucaccgu ugcuuugucc       60

uuaucuacau guucaacucu ggacauggau caguuuauga gaaagaggau ugaggcaaua      120

cggggccaaa uccuaaguaa acucaagcug acgagcccuc ccgaagacua uccagagccg      180

gaagaggugc ccccugaagu aauuuccauc uacaacucua cccgcgaucu ucugcaggag      240

aaagccucgc gacgugcggc ugccugcgag agagaaaggu cagacgagga auauuacgca      300

aaggaggugu auaaaauuga uaugccaccc uucuuuccua gcgagaaugc caucccaccc      360

acauucuacc ggccuuauuu ucgcauaguc agauucgacg ugagugcuau ggaaaagaac      420

gcauccaauu ugguuaaggc cgaguuuagg guguuccggc uccagaaccc aaaagcucgc      480

gucccggaac agcgaaucga gcuguaccaa auucugaagu cuaaagaucu cacuagcccc      540

acccagagau acaucgacuc caagguggua aaaacaaggg ccgaagggga gugguuauca      600

uuugauguua ccgacgcggu gcacgagugg cugcaucaca aggaucggaa ucuuggauuc      660

aagauuaguu ugcauugucc uugcuguacu uuugucccaa gcaacaauua uaucauaccc      720

aacaaaucug aggaacugga agcacguuuc gccgguauug acggcacauc caccuacacg      780

ucaggggauc agaagacuau caaaagcacc cgcaagaaaa auaguggaaa gacaccucac      840

cuacuccuga ugcuucugcc aucuuauaga uuggaguccc agcaaacuaa caggcggaaa      900

aagcgagcuc ucgacgccgc auacugcuuu cgcaaugugc aggacaacug uugccugaga      960

cccuuauaua uugauuucaa gagggaccug ggcuggaaau ggauccacga accgaagggu     1020

uacaaugcua acuucugugc cggggcgugc ccuuaucucu ggagcucgga uacccagcau     1080

ucucgggugc uuucccugua caauacaauc aaccccgagg ccucagcaag uccauguugc     1140

gucagccagg acuuggagcc ucuaaccauu cuguacuaua uaggaaaaac gcccaagauc     1200

gaacaacucu ccaacaugau uguuaaaucu ugcaagugua gcuga                     1245


<210>  494
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  494
augaagaugc aucugcagag agcccucgug guccuugcuc uguugaacuu cgcaaccguu       60

agcuuauccc ugucuacaug cacuacgcua gacuuuggcc acaucaaaaa gaaaagggug      120

gaggccauuc gggggcaaau acucucaaag cugcgccuua ccaguccccc ugaaccaaca      180

guaaugacuc acgugccgua ccagguccug gcguuguaua auagcacccg agagcuccug      240

gaagagaugc auggagaacg ugaggagggu uguacacagg aaaacaccga guccgaauac      300

uaugcuaaag agauccacaa guucgauaug auucagggcc uggccgagca uaaugaacuc      360

gcagugugcc ccaaggggau cacuucuaaa guuuuuagau ucaacguguc gucagucgag      420

aagaauagga caaacuuauu ucgggccgag uuccgcgugc ugagaguacc uaauccaagc      480

aguaaaagga acgaacaacg gauugaacuu uuucagaucu ugcgccccga cgagcacaua      540

gcuaagcagc gauacaucgg aggcaaaaau cugccuacca gagguacggc agaguggcua      600

uccuucgaug uuacugacac cgugagggaa uggcuccugc ggcgugaguc uaaccuuggg      660

cuggaaauua gcauccacug uccaugccau acauuucagc ccaauggaga uauuuuggag      720

aacauccacg aagucaugga gauaaaguuc aagggcgugg acaaugagga ugaccauggc      780

cgcggggauc ucggaagacu gaaaaagcaa aaagaccacc acaacccuca uuuaauucug      840

augaugaucc caccgcacag gcucgauaau cccggucagg gcgggcagcg gaagaaacga      900

gcccuugaca cuaacuauug uuuucgcaac cuggaagaga auugcugugu gagaccuuug      960

uacauugauu ucaggcagga ccuaggaugg aagugggucc augaaccaaa aggcuauuac     1020

gcuaacuuuu gcuccggucc cuguccuuac cugcggucag ccgacaccac acacaguacc     1080

guucucgggc uguauaauac gcuuaaccca gaggcgagcg caucucccug cugugugccg     1140

caagaucugg aaccuuugac uauccucuac uauguaggac gcacacccaa gguggagcag     1200

cuguccaaua uggucgugaa gucaugcaaa ugcagcuga                            1239


<210>  495
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  495
auggcccccg uggcugucug ggcagcccug gcgguuggcc ucgagcuuug ggcugccgca       60

cacgcccugc cugcucaggu ggcauucacc ccauacgccc cggaacccgg gagcacaugc      120

agauugaggg aguauuacga ccaaacugcu cagauguguu gcuccaagug uucuccugga      180

cagcaugcca aaguauuuug cacgaagacc ucagauacag ugugugacag uugcgaagau      240

agcacuuaua cccaguuaug gaacuggguc ccagaguguc uguccugcgg uucucggugu      300

ucgucagacc aaguggaaac acaggcgugc acccgcgagc agaaucgaau cuguacuugc      360

cgucccggcu gguacugcgc acuaagcaaa caggaggggu guagacucug cgccccucug      420

aggaaguguc ggccaggauu cggcguugcu cgccccggua cagaaaccag ugaugugguc      480

ugcaaaccuu gugccccagg gacguuuucc aacacuaccu cuagcacaga cauuugcaga      540

ccgcaccaaa uauguaaugu gguagcaauc cccggaaacg cuuccaugga ugccguuugc      600

acuucaacca guccuacaag gagcauggcg ccaggcgccg ugcaucuucc ccagccuguc      660

ucuacccggu cccagcacac gcagccaacu cccgagccgu caacagcacc uagcaccagu      720

uuccuguugc ccaugggccc aucuccuccc gcugaagggu ccacuggaga cuuugcccuc      780

ccaguggguc ugauuguggg cgucacagcu cuggggcucu uaaucauugg aguugugaau      840

uguguaauca ugacccaagu gaagaagaaa ccccugugcc uucagcgcga ggccaagguc      900

ccucauuugc cagcagauaa agcccgaggc acgcaggguc cggagcaaca gcaucugcua      960

auaaccgcuc ccagcucguc uuccucaagu cucgaaagcu ccgcgucugc acuggacaga     1020

agggccccua cacggaacca gccacaggcu cccggggugg aggccagcgg agcaggcgaa     1080

gcccgugcuu caacuggcag uuccgauagc ucuccugggg gacacgguac ccaaguuaau     1140

gugacaugua ucgucaacgu gugcucaagu agcgaccacu ccucucagug cucgagccag     1200

gccuccucaa cuaugggcga uaccgacagu ucuccaagcg agucccccaa ggacgaacag     1260

guaccguucu caaaagagga gugugcauuu cgcagccaac uugaaacacc ugagacccug     1320

uuggggucua cugaagagaa gccacucccc cugggaguuc cugaugcggg caugaagccc     1380

uccuga                                                                1386


<210>  496
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  496
augcccguga ugagacuguu cccuugcuuu cuccagcuuc uggccggcuu ggcuuuacca       60

gcagucccgc cccaacagug ggcccugagc gcggggaacg gauccucuga gguugaagug      120

guaccuuucc aggaggugug ggguagguca uacugucggg cucuagaacg ccucgucgac      180

gugguuagug aguauccaag cgaaguggag cacauguuuu cccccucuug cgucucgcug      240

cuucgaugua ccggcugcug uggggaugag aaucugcauu gcgugccugu agaaacagcc      300

aacguuacua ugcaguugcu caagauccgu ucaggagaca gaccaagcua cguggagcug      360

acguucaguc aacacgucag gugugaaugc cggccccugc gcgagaaaau gaagccugag      420

agaaggcggc caaaaggccg cgguaagcga agaagggaaa aacagcggcc gaccgauugu      480

caucucugcg gggacgcagu gccccgucgc uga                                   513


<210>  497
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  497
augaccgaca gacagacaga uacugccccc agcccuuccu accaucugcu cccaggcagg       60

cggcgcacgg uggacgcugc agccucucga gggcaaggac cggagcccgc gccugguggc      120

ggggucgaag gaguuggcgc ucguggugug gcccuuaagc uguucguaca guuguuaggg      180

ugcucaagau uuggaggcgc aguggucagg gccggcgagg cugaaccaag uggggcagcc      240

cggagcgcuu ccucuggacg cgaggaaccc cagccugagg agggugaaga ggaagaggag      300

aaagaagagg aaagaggccc acaguggagg cugggggccc ggaagcccgg aucguggacc      360

ggcgaggcgg cagugugugc cgauucagcu ccugccgcac gcgcuccaca agcccuagcg      420

cgagccagcg guagaggggg aaggguugca cggcguggcg cugaagagag uggcccgccc      480

cacuccccuu cucgcagagg gagcgccucc agggcuggac caggucgggc cucagagaca      540

augaacuucc uccugaguug ggugcacugg agccuugcac uguugcucua ucugcaucac      600

gccaaauggu cucaggcugc gcccauggca gaaggcgggg gacagaauca ucacgagguc      660

gugaaguuua uggacguaua ccagcgaucc uauugccacc cuaucgaaac ucugguugau      720

auuuuccaag aguacccaga cgaaauagag uauaucuuua aacccucaug ugugccgcuc      780

augcgcugcg gcgguuguug caacgaugag ggguuagaau gugucccuac cgaggaaagc      840

aauauuacaa ugcagaucau gagaauuaag ccccaucagg gccagcacau cggagagaug      900

aguuuccugc aacauaacaa gugcgaaugu aggccuaaaa aggaccgggc ccgccaggag      960

aaaaagucug ugagaggcaa agggaaggga cagaagagga aacguaagaa aucccgguac     1020

aagagcuggu cgguguaugu cggugcucga ugcugucuua ugccaugguc uuugcccggc     1080

ccacaccccu gcgggccuug cuccgagaga aggaaacacc uguuuguuca agauccacag     1140

accuguaagu gcucauguaa aaauacugac agucgcugca aggcccggca gcuagaacuc     1200

aacgagagaa cauguaggug cgauaagccg cgccgauga                            1239


<210>  498
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  498
augaacuucc ugcucagcug ggugcacugg ucccuugccc uguuguuaua ccugcaucac       60

gcuaaguggu cucaggcagc ccccauggcg gagggcgggg gacaaaauca ucacgaaguc      120

guuaaauuua uggacgugua ucagagauca uacugccauc cuaucgagac ccuaguagau      180

auuuuccagg aauauccaga cgagauagaa uacaucuuua agccgaguug ugugccccuc      240

augaggugcg guggcuguug caacgaugag gggcuggagu gugucccuac agaagagagc      300

aauauuacua ugcagaucau gcggauuaaa ccacaccaag gacagcacau cggcgaaaug      360

uccuuccuuc agcauaacaa gugcgagugu cgccccaaaa aggaccgagc ucgucaggag      420

aagaaaucug ugagagguaa ggggaaagga caaaagagga aacggaagaa gucgcgcuau      480

aaaucaugga gcguuuacgu gggcgccaga ugcugucuga ugccuuggag uuugccaggc      540

ccccacccuu gcgggccaug uuccgaaagg cggaagcauc ucuuugucca ggauccgcag      600

acgugcaaau gcucuuguaa gaauaccgac agccgcugca aagcacgaca gcuggagcug      660

aacgaaagaa cauguaggug cgauaagccc cggcguuga                             699


<210>  499
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  499
augagccccc ugcucagaag gcuucuguug gccgcuuuac ugcagcuagc cccugcacaa       60

gcgccagugu cccagccgga cgcucccggc caccagcgga aggucguuuc uuggaucgau      120

guguacaccc gcgccacaug ccagccucga gagguagugg ucccacucac uguggaacug      180

auggggacgg uugcaaaaca acuugugccc ucauguguca ccgugcagcg uugcggaggu      240

uguugcccug acgauggccu ggagugugua ccaacagggc agcaucaggu uagaaugcaa      300

auuuugauga uaagguaucc caguagccag cucggagaaa ugucccugga ggaacacucu      360

cagugcgagu gucggccuaa gaaaaaggac ucggccguga aaccagaucg cgcugcaacu      420

ccgcaucaca gaccccagcc uaggucaguc ccaggcuggg acagcgcccc cggugcuccu      480

aguccagccg auaucaccca ucccacaccg gcgccugggc ccuccgcaca cgccgcucca      540

ucuaccacua gcgcccugac accuggaccc gcagcugccg cggccgacgc agcugccucc      600

ucaguggcua agggcggcgc cuga                                             624


<210>  500
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  500
augcaccuuc ucggcuucuu uagcguggcc ugcucccuuc uggcugcagc cuuguuaccc       60

gggccuagag aggcgccagc ugccgcagcc gcuuucgaau cuggacugga ccuaucagau      120

gcagagccgg acgccgguga agcuaccgcc uacgcgagua aggaucucga ggaacagcug      180

aggagcgucu ccucuguuga cgagcuuaug acagugcugu aucccgagua cuggaaaaug      240

uauaaguguc aauugcggaa aggcgggugg cagcauaacc gcgaacaggc aaaucucaac      300

ucgcgaacug aggaaacgau caaguuugcc gcugcccacu acaauaccga gauucugaaa      360

ucaauagaua acgaguggcg uaagacacag ugcaugccua gagaaguaug uaucgacgug      420

ggaaaggagu ucggcgucgc aacuaauacc uuuuucaaac cacccugcgu gagcguuuau      480

agguguggug ggugcuguaa cagugaagga cugcaaugca ugaauacauc caccucuuac      540

cucagcaaga cuuuauuuga gauuacagug ccucuguccc agggcccaaa acccgucacc      600

aucucauucg cuaaccauac gaguugucgg ugcaugagca agcuggaugu guaucgccag      660

guacacucua uuaucagaag guccuugccu gccacucugc cacaguguca agcggccaau      720

aaaaccugcc cgacaaacua cauguggaau aaccauauau gccggugucu agcacaggaa      780

gacuuuaugu ucucaagcga ugcuggcgac gauaguacug acggguuuca cgauaucugc      840

ggacccaaua aggagcucga cgaggaaacc ugucagugcg uuugucgcgc cggucugcga      900

ccugcuucuu gcggcccaca caaggagcuu gacagaaacu ccugucagug cguguguaaa      960

aauaagcugu uccccagcca augcggggcc aacagggaau uugaugagaa cacaugucag     1020

ugcgucugca aacggaccug uccucguaau cagccauuga accccggaaa gugcgcaugu     1080

gaaugcacgg agucgccgca aaaaugucuc cugaagggca aaaaguucca ucaccagacu     1140

ugcucuuguu accgcagacc uugcacaaau aggcagaagg ccugugagcc cgguuucucc     1200

uauucagaag aggugugccg gugugugcca aguuacugga aacgaccuca gaugagcuga     1260


<210>  501
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  501
auguacagag aguggguggu cguuaacgug uucaugaugc uguauguaca gcucgugcaa       60

ggcagcucca augaacacgg gcccgucaag aggucuucac agaguacccu ugagcggagc      120

gaacagcaga uccgcgccgc uuccucucug gaggaauugu uacgaauuac acauucggag      180

gacuggaaac uguggcguug cagacuaagg cucaagucau uuacuagcau ggauagucgg      240

uccgcaucuc accgcagcac gagauucgcc gcgaccuuuu acgacauaga gacacugaaa      300

gugaucgaug aagaguggca aaggacucag uguuccccuc gggaaaccug cguugaggug      360

gcuucagagc uuggaaagag uacaaacacc uucuuuaaac caccgugugu caauguguuc      420

cgcugcggug gcuguugcaa cgaagagagc cugauuugua ugaauacuuc uacauccuau      480

aucucaaagc aguuguuuga aauuagcgua ccccucacca guguuccuga gcuggugcca      540

gucaaggugg ccaaccauac ggggugcaaa ugucugccca cugcaccucg acacccauac      600

ucuaucauaa gaagguccau ccagauuccc gaagaggacc ggugcagcca uucgaagaaa      660

cucuguccua ucgauauguu augggacucu aauaagugca aaugcgugcu gcaagaggaa      720

aacccacuug ccggaaccga ggaucacucc cacuugcagg aaccggcucu guguggcccc      780

cauaugaugu ucgacgagga ucguugcgaa ugugucugca agacaccuug uccaaaggac      840

cuaauucagc accccaaaaa uugcucaugu uuugagugca aggagagucu cgaaacuugu      900

ugccagaaac auaagcuguu ccacccugau accuguagcu gcgaggaccg cugcccauuu      960

cacacaagac ccugugcauc cgguaaaacc gccugcgcua agcauuguag guucccgaaa     1020

gaaaagcggg ccgcgcaagg gccucacucu cgaaagaacc ccuga                     1065


<210>  502
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  502
auggccguga uggcccccag aacccuggug cugcugcuga gcggcgcccu ggcccugacc       60

cagaccuggg cc                                                           72


<210>  503
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  503
auggacgcca ugaagagagg ccugugcugc gugcugcugc ugugcggcgc cguguucgug       60

agccccagc                                                               69


<210>  504
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  504
augggcgugc acgagugccc cgccuggcug uggcugcugc ugagccugcu gagccugccc       60

cugggccugc ccgugcuggg c                                                 81


<210>  505
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  505
augaaguggg ugaccuucau cagccugcug uuccuguuca gcagcgccua cagc             54


<210>  506
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from 
       Artificial____cleavage site-Furin

<400>  506
agaagaagaa gaaagaga                                                     18


<210>  507
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  507
auggacagcg acgagaccgg cuucgagcac agcggccugu gggugagcgu gcuggccggc       60

cugcugcugg gcgccugcca ggcccacccc auccccgaca gcagcccccu gcugcaguuc      120

ggcggccagg ugagacagag auaccuguac accgacgacg cccagcagac cgaggcccac      180

cuggagauca gagaggacgg caccgugggc ggcgccgccg accagagccc cgagagccug      240

cugcagcuga aggcccugaa gcccggcgug auccagaucc ugggcgugaa gaccagcaga      300

uuccugugcc agagacccga cggcgcccug uacggcagcc ugcacuucga ccccgaggcc      360

ugcagcuuca gagagcugcu gcuggaggac ggcuacaacg uguaccagag cgaggcccac      420

ggccugcccc ugcaccugcc cggcaacaag agcccccaca gagaccccgc ccccagaggc      480

cccgccagau uccugccccu gcccggccug ccccccgccc ugcccgagcc ccccggcauc      540

cuggcccccc agccccccga cgugggcagc agcgaccccc ugagcauggu gggccccagc      600

cagggcagaa gccccagcua cgccagcuga                                       630


<210>  508
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  508
augcacagcu uccccccccu gcugcugcug cuguucuggg gcguggugag ccacagcuuc       60

cccgccaccc uggagaccca ggagcaggac guggaccugg ugcagaagua ccuggagaag      120

uacuacaacc ugaagaacga cggcagacag guggagaaga gaagaaacag cggccccgug      180

guggagaagc ugaagcagau gcaggaguuc uucggccuga aggugaccgg caagcccgac      240

gccgagaccc ugaaggugau gaagcagccc agaugcggcg ugcccgacgu ggcccaguuc      300

gugcugaccg agggcaaccc cagaugggag cagacccacc ugaccuacag aaucgagaac      360

uacacccccg accugcccag agccgacgug gaccacgcca ucgagaaggc cuuccagcug      420

uggagcaacg ugaccccccu gaccuucacc aaggugagcg agggccaggc cgacaucaug      480

aucagcuucg ugagaggcga ccacagagac aacagccccu ucgacggccc cggcggcaac      540

cuggcccacg ccuuccagcc cggccccggc aucggcggcg acgcccacuu cgacgaggac      600

gagagaugga ccaacaacuu cagagaguac aaccugcaca gaguggccgc ccacgagcug      660

ggccacagcc ugggccugag ccacagcacc gacaucggcg cccugaugua ccccagcuac      720

accuucagcg gcgacgugca gcuggcccag gacgacaucg acggcaucca ggccaucuac      780

ggcagaagcc agaaccccgu gcagcccauc ggcccccaga cccccaaggc cugcgacagc      840

aagcugaccu ucgacgccau caccaccauc agaggcgagg ugauguucuu caaggacaga      900

uucuacauga gaaccaaccc cuucuacccc gagguggagc ugaacuucau cagcguguuc      960

uggccccagc ugcccaacgg ccuggaggcc gccuacgagu ucgccgacag agacgaggug     1020

agauucuuca agggcaacaa guacugggcc gugcagggcc agaacgugcu gcacggcuac     1080

cccaaggaca ucuacagcag cuucggcuuc cccagaaccg ugaagcacau cgacgccgcc     1140

cugagcgagg agaacaccgg caagaccuac uucuucgugg ccaacaagua cuggagauac     1200

gacgaguaca agagaagcau ggaccccggc uaccccaaga ugaucgccca cgacuucccc     1260

ggcaucggcc acaaggugga cgccguguuc augaaggacg gcuucuucua cuucuuccac     1320

ggcaccagac aguacaaguu cgaccccaag accaagagaa uccugacccu gcagaaggcc     1380

aacagcuggu ucaacugcag aaagaacuga                                      1410


<210>  509
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  509
augcacagcu uccccccccu gcugcugcug cuguucuggg gcguggugag ccacagcuuc       60

gugcugaccg agggcaaccc cagaugggag cagacccacc ugaccuacag aaucgagaac      120

uacacccccg accugcccag agccgacgug gaccacgcca ucgagaaggc cuuccagcug      180

uggagcaacg ugaccccccu gaccuucacc aaggugagcg agggccaggc cgacaucaug      240

aucagcuucg ugagaggcga ccacagagac aacagccccu ucgacggccc cggcggcaac      300

cuggcccacg ccuuccagcc cggccccggc aucggcggcg acgcccacuu cgacgaggac      360

gagagaugga ccaacaacuu cagagaguac aaccugcaca gaguggccgc ccacgagcug      420

ggccacagcc ugggccugag ccacagcacc gacaucggcg cccugaugua ccccagcuac      480

accuucagcg gcgacgugca gcuggcccag gacgacaucg acggcaucca ggccaucuac      540

ggcagaagcc agaaccccgu gcagcccauc ggcccccaga cccccaaggc cugcgacagc      600

aagcugaccu ucgacgccau caccaccauc agaggcgagg ugauguucuu caaggacaga      660

uucuacauga gaaccaaccc cuucuacccc gagguggagc ugaacuucau cagcguguuc      720

uggccccagc ugcccaacgg ccuggaggcc gccuacgagu ucgccgacag agacgaggug      780

agauucuuca agggcaacaa guacugggcc gugcagggcc agaacgugcu gcacggcuac      840

cccaaggaca ucuacagcag cuucggcuuc cccagaaccg ugaagcacau cgacgccgcc      900

cugagcgagg agaacaccgg caagaccuac uucuucgugg ccaacaagua cuggagauac      960

gacgaguaca agagaagcau ggaccccggc uaccccaaga ugaucgccca cgacuucccc     1020

ggcaucggcc acaaggugga cgccguguuc augaaggacg gcuucuucua cuucuuccac     1080

ggcaccagac aguacaaguu cgaccccaag accaagagaa uccugacccu gcagaaggcc     1140

aacagcuggu ucaacugcag aaagaacuga                                      1170


<210>  510
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  510
augaagaaga acauccugaa gauccugaug gacagcuaca gcaaggagag caagauccag       60

accgugagaa gagugaccag cgugagccug cuggccgugu accugaccau gaacaccagc      120

agccuggugc uggccaagcc caucgagaac accaacgaca ccagcaucaa gaacguggag      180

aagcugagaa acgcccccaa cgaggagaac agcaagaagg uggaggacag caagaacgac      240

aagguggagc acgugaagaa caucgaggag gccaaggugg agcagguggc ccccgaggug      300

aagagcaaga gcacccugag aagcgccagc aucgccaaca ccaacagcga gaaguacgac      360

uucgaguacc ugaacggccu gagcuacacc gagcugacca accugaucaa gaacaucaag      420

uggaaccaga ucaacggccu guucaacuac agcaccggca gccagaaguu cuucggcgac      480

aagaacagag ugcaggccau caucaacgcc cugcaggaga gcggcagaac cuacaccgcc      540

aacgacauga agggcaucga gaccuucacc gaggugcuga gagccggcuu cuaccugggc      600

uacuacaacg acggccugag cuaccugaac gacagaaacu uccaggacaa gugcaucccc      660

gccaugaucg ccauccagaa gaaccccaac uucaagcugg gcaccgccgu gcaggacgag      720

gugaucacca gccugggcaa gcugaucggc aacgccagcg ccaacgccga gguggugaac      780

aacugcgugc ccgugcugaa gcaguucaga gagaaccuga accaguacgc ccccgacuac      840

gugaagggca ccgccgugaa cgagcugauc aagggcaucg aguucgacuu cagcggcgcc      900

gccuacgaga aggacgugaa gaccaugccc ugguacggca agaucgaccc cuucaucaac      960

gagcugaagg cccugggccu guacggcaac aucaccagcg ccaccgagug ggccagcgac     1020

gugggcaucu acuaccugag caaguucggc cuguacagca ccaacagaaa cgacaucgug     1080

cagagccugg agaaggccgu ggacauguac aaguacggca agaucgccuu cguggccaug     1140

gagagaauca ccugggacua cgacggcauc ggcagcaacg gcaagaaggu ggaccacgac     1200

aaguuccugg acgacgccga gaagcacuac cugcccaaga ccuacaccuu cgacaacggc     1260

accuucauca ucagagccgg cgacaaggug agcgaggaga agaucaagag acuguacugg     1320

gccagcagag aggugaagag ccaguuccac agaguggugg gcaacgacaa ggcccuggag     1380

gugggcaacg ccgacgacgu gcugaccaug aagaucuuca acagccccga ggaguacaag     1440

uucaacacca acaucaacgg cgugagcacc gacaacggcg gccuguacau cgagcccaga     1500

ggcaccuucu acaccuacga gagaaccccc cagcagagca ucuucagccu ggaggagcug     1560

uucagacacg aguacaccca cuaccugcag gccagauacc ugguggacgg ccuguggggc     1620

cagggccccu ucuacgagaa gaacagacug accugguucg acgagggcac cgccgaguuc     1680

uucgccggca gcaccagaac cagcggcgug cugcccagaa agagcauccu gggcuaccug     1740

gccaaggaca agguggacca cagauacagc cugaagaaga cccugaacag cggcuacgac     1800

gacagcgacu ggauguucua caacuacggc uucgccgugg cccacuaccu guacgagaag     1860

gacaugccca ccuucaucaa gaugaacaag gccauccuga acaccgacgu gaagagcuac     1920

gacgagauca ucaagaagcu gagcgacgac gccaacaaga acaccgagua ccagaaccac     1980

auccaggagc uggccgacaa guaccagggc gccggcaucc cccuggugag cgacgacuac     2040

cugaaggacc acggcuacaa gaaggccagc gagguguaca gcgagaucag caaggccgcc     2100

agccugacca acaccagcgu gaccgccgag aagagccagu acuucaacac cuucacccug     2160

agaggcaccu acaccggcga gaccagcaag ggcgaguuca aggacuggga cgagaugagc     2220

aagaagcugg acggcacccu ggagagccug gccaagaaca gcuggagcgg cuacaagacc     2280

cugaccgccu acuucaccaa cuacagagug accagcgaca acaaggugca guacgacgug     2340

guguuccacg gcgugcugac cgacaacgcc gacaucagca acaacaaggc ccccaucgcc     2400

aaggugaccg gccccagcac cggcgccgug ggcagaaaca ucgaguucag cggcaaggac     2460

agcaaggacg aggacggcaa gaucgugagc uacgacuggg acuucggcga cggcgccacc     2520

agcagaggca agaacagcgu gcacgccuac aagaaggccg gcaccuacaa cgugacccug     2580

aaggugaccg acgacaaggg cgccaccgcc accgagagcu ucaccaucga gaucaagaac     2640

gaggacacca ccacccccau caccaaggag auggagccca acgacgacau caaggaggcc     2700

aacggcccca ucguggaggg cgugaccgug aagggcgacc ugaacggcag cgacgacgcc     2760

gacaccuucu acuucgacgu gaaggaggac ggcgacguga ccaucgagcu gcccuacagc     2820

ggcagcagca acuucaccug gcugguguac aaggagggcg acgaccagaa ccacaucgcc     2880

agcggcaucg acaagaacaa cagcaaggug ggcaccuuca agagcaccaa gggcagacac     2940

uacguguuca ucuacaagca cgacagcgcc agcaacauca gcuacagccu gaacaucaag     3000

ggccugggca acgagaagcu gaaggagaag gagaacaacg acagcagcga caaggccacc     3060

gugaucccca acuucaacac caccaugcag ggcagccugc ugggcgacga cagcagagac     3120

uacuacagcu ucgaggugaa ggaggagggc gaggugaaca ucgagcugga caagaaggac     3180

gaguucggcg ugaccuggac ccugcacccc gagagcaaca ucaacgacag aaucaccuac     3240

ggccaggugg acggcaacaa ggugagcaac aaggugaagc ugagacccgg caaguacuac     3300

cugcuggugu acaaguacag cggcagcggc aacuacgagc ugagagugaa caaguga        3357


<210>  511
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  511
augaaguggg ugaccuucau cagccugcug uuccuguuca gcagcgccua cagcaucgcc       60

aacaccaaca gcgagaagua cgacuucgag uaccugaacg gccugagcua caccgagcug      120

accaaccuga ucaagaacau caaguggaac cagaucaacg gccuguucaa cuacagcacc      180

ggcagccaga aguucuucgg cgacaagaac agagugcagg ccaucaucaa cgcccugcag      240

gagagcggca gaaccuacac cgccaacgac augaagggca ucgagaccuu caccgaggug      300

cugagagccg gcuucuaccu gggcuacuac aacgacggcc ugagcuaccu gaacgacaga      360

aacuuccagg acaagugcau ccccgccaug aucgccaucc agaagaaccc caacuucaag      420

cugggcaccg ccgugcagga cgaggugauc accagccugg gcaagcugau cggcaacgcc      480

agcgccaacg ccgagguggu gaacaacugc gugcccgugc ugaagcaguu cagagagaac      540

cugaaccagu acgcccccga cuacgugaag ggcaccgccg ugaacgagcu gaucaagggc      600

aucgaguucg acuucagcgg cgccgccuac gagaaggacg ugaagaccau gcccugguac      660

ggcaagaucg accccuucau caacgagcug aaggcccugg gccuguacgg caacaucacc      720

agcgccaccg agugggccag cgacgugggc aucuacuacc ugagcaaguu cggccuguac      780

agcaccaaca gaaacgacau cgugcagagc cuggagaagg ccguggacau guacaaguac      840

ggcaagaucg ccuucguggc cauggagaga aucaccuggg acuacgacgg caucggcagc      900

aacggcaaga agguggacca cgacaaguuc cuggacgacg ccgagaagca cuaccugccc      960

aagaccuaca ccuucgacaa cggcaccuuc aucaucagag ccggcgacaa ggugagcgag     1020

gagaagauca agagacugua cugggccagc agagagguga agagccaguu ccacagagug     1080

gugggcaacg acaaggcccu ggaggugggc aacgccgacg acgugcugac caugaagauc     1140

uucaacagcc ccgaggagua caaguucaac accaacauca acggcgugag caccgacaac     1200

ggcggccugu acaucgagcc cagaggcacc uucuacaccu acgagagaac cccccagcag     1260

agcaucuuca gccuggagga gcuguucaga cacgaguaca cccacuaccu gcaggccaga     1320

uaccuggugg acggccugug gggccagggc cccuucuacg agaagaacag acugaccugg     1380

uucgacgagg gcaccgccga guucuucgcc ggcagcacca gaaccagcgg cgugcugccc     1440

agaaagagca uccugggcua ccuggccaag gacaaggugg accacagaua cagccugaag     1500

aagacccuga acagcggcua cgacgacagc gacuggaugu ucuacaacua cggcuucgcc     1560

guggcccacu accuguacga gaaggacaug cccaccuuca ucaagaugaa caaggccauc     1620

cugaacaccg acgugaagag cuacgacgag aucaucaaga agcugagcga cgacgccaac     1680

aagaacaccg aguaccagaa ccacauccag gagcuggccg acaaguacca gggcgccggc     1740

aucccccugg ugagcgacga cuaccugaag gaccacggcu acaagaaggc cagcgaggug     1800

uacagcgaga ucagcaaggc cgccagccug accaacacca gcgugaccgc cgagaagagc     1860

caguacuuca acaccuucac ccugagaggc accuacaccg gcgagaccag caagggcgag     1920

uucaaggacu gggacgagau gagcaagaag cuggacggca cccuggagag ccuggccaag     1980

aacagcugga gcggcuacaa gacccugacc gccuacuuca ccaacuacag agugaccagc     2040

gacaacaagg ugcaguacga cgugguguuc cacggcgugc ugaccgacaa cgccgacauc     2100

agcaacaaca aggcccccau cgccaaggug accggcccca gcaccggcgc cgugggcaga     2160

aacaucgagu ucagcggcaa ggacagcaag gacgaggacg gcaagaucgu gagcuacgac     2220

ugggacuucg gcgacggcgc caccagcaga ggcaagaaca gcgugcacgc cuacaagaag     2280

gccggcaccu acaacgugac ccugaaggug accgacgaca agggcgccac cgccaccgag     2340

agcuucacca ucgagaucaa gaacgaggac accaccaccc ccaucaccaa ggagauggag     2400

cccaacgacg acaucaagga ggccaacggc cccaucgugg agggcgugac cgugaagggc     2460

gaccugaacg gcagcgacga cgccgacacc uucuacuucg acgugaagga ggacggcgac     2520

gugaccaucg agcugcccua cagcggcagc agcaacuuca ccuggcuggu guacaaggag     2580

ggcgacgacc agaaccacau cgccagcggc aucgacaaga acaacagcaa ggugggcacc     2640

uucaagagca ccaagggcag acacuacgug uucaucuaca agcacgacag cgccagcaac     2700

aucagcuaca gccugaacau caagggccug ggcaacgaga agcugaagga gaaggagaac     2760

aacgacagca gcgacaaggc caccgugauc cccaacuuca acaccaccau gcagggcagc     2820

cugcugggcg acgacagcag agacuacuac agcuucgagg ugaaggagga gggcgaggug     2880

aacaucgagc uggacaagaa ggacgaguuc ggcgugaccu ggacccugca ccccgagagc     2940

aacaucaacg acagaaucac cuacggccag guggacggca acaaggugag caacaaggug     3000

aagcugagac ccggcaagua cuaccugcug guguacaagu acagcggcag cggcaacuac     3060

gagcugagag ugaacaagug a                                               3081


<210>  512
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  512
augaaguggg ugaccuucau cagccugcug uuccuguuca gcagcgccua cagcaugaag       60

aagaacaucc ugaagauccu gauggacagc uacagcaagg agagcaagau ccagaccgug      120

agaagaguga ccagcgugag ccugcuggcc guguaccuga ccaugaacac cagcagccug      180

gugcuggcca agcccaucga gaacaccaac gacaccagca ucaagaacgu ggagaagcug      240

agaaacgccc ccaacgagga gaacagcaag aagguggagg acagcaagaa cgacaaggug      300

gagcacguga agaacaucga ggaggccaag guggagcagg uggcccccga ggugaagagc      360

aagagcaccc ugagaagcgc cagcagaaga agaagaaaga gaaucgccaa caccaacagc      420

gagaaguacg acuucgagua ccugaacggc cugagcuaca ccgagcugac caaccugauc      480

aagaacauca aguggaacca gaucaacggc cuguucaacu acagcaccgg cagccagaag      540

uucuucggcg acaagaacag agugcaggcc aucaucaacg cccugcagga gagcggcaga      600

accuacaccg ccaacgacau gaagggcauc gagaccuuca ccgaggugcu gagagccggc      660

uucuaccugg gcuacuacaa cgacggccug agcuaccuga acgacagaaa cuuccaggac      720

aagugcaucc ccgccaugau cgccauccag aagaacccca acuucaagcu gggcaccgcc      780

gugcaggacg aggugaucac cagccugggc aagcugaucg gcaacgccag cgccaacgcc      840

gaggugguga acaacugcgu gcccgugcug aagcaguuca gagagaaccu gaaccaguac      900

gcccccgacu acgugaaggg caccgccgug aacgagcuga ucaagggcau cgaguucgac      960

uucagcggcg ccgccuacga gaaggacgug aagaccaugc ccugguacgg caagaucgac     1020

cccuucauca acgagcugaa ggcccugggc cuguacggca acaucaccag cgccaccgag     1080

ugggccagcg acgugggcau cuacuaccug agcaaguucg gccuguacag caccaacaga     1140

aacgacaucg ugcagagccu ggagaaggcc guggacaugu acaaguacgg caagaucgcc     1200

uucguggcca uggagagaau caccugggac uacgacggca ucggcagcaa cggcaagaag     1260

guggaccacg acaaguuccu ggacgacgcc gagaagcacu accugcccaa gaccuacacc     1320

uucgacaacg gcaccuucau caucagagcc ggcgacaagg ugagcgagga gaagaucaag     1380

agacuguacu gggccagcag agaggugaag agccaguucc acagaguggu gggcaacgac     1440

aaggcccugg aggugggcaa cgccgacgac gugcugacca ugaagaucuu caacagcccc     1500

gaggaguaca aguucaacac caacaucaac ggcgugagca ccgacaacgg cggccuguac     1560

aucgagccca gaggcaccuu cuacaccuac gagagaaccc cccagcagag caucuucagc     1620

cuggaggagc uguucagaca cgaguacacc cacuaccugc aggccagaua ccugguggac     1680

ggccuguggg gccagggccc cuucuacgag aagaacagac ugaccugguu cgacgagggc     1740

accgccgagu ucuucgccgg cagcaccaga accagcggcg ugcugcccag aaagagcauc     1800

cugggcuacc uggccaagga caagguggac cacagauaca gccugaagaa gacccugaac     1860

agcggcuacg acgacagcga cuggauguuc uacaacuacg gcuucgccgu ggcccacuac     1920

cuguacgaga aggacaugcc caccuucauc aagaugaaca aggccauccu gaacaccgac     1980

gugaagagcu acgacgagau caucaagaag cugagcgacg acgccaacaa gaacaccgag     2040

uaccagaacc acauccagga gcuggccgac aaguaccagg gcgccggcau cccccuggug     2100

agcgacgacu accugaagga ccacggcuac aagaaggcca gcgaggugua cagcgagauc     2160

agcaaggccg ccagccugac caacaccagc gugaccgccg agaagagcca guacuucaac     2220

accuucaccc ugagaggcac cuacaccggc gagaccagca agggcgaguu caaggacugg     2280

gacgagauga gcaagaagcu ggacggcacc cuggagagcc uggccaagaa cagcuggagc     2340

ggcuacaaga cccugaccgc cuacuucacc aacuacagag ugaccagcga caacaaggug     2400

caguacgacg ugguguucca cggcgugcug accgacaacg ccgacaucag caacaacaag     2460

gcccccaucg ccaaggugac cggccccagc accggcgccg ugggcagaaa caucgaguuc     2520

agcggcaagg acagcaagga cgaggacggc aagaucguga gcuacgacug ggacuucggc     2580

gacggcgcca ccagcagagg caagaacagc gugcacgccu acaagaaggc cggcaccuac     2640

aacgugaccc ugaaggugac cgacgacaag ggcgccaccg ccaccgagag cuucaccauc     2700

gagaucaaga acgaggacac caccaccccc aucaccaagg agauggagcc caacgacgac     2760

aucaaggagg ccaacggccc caucguggag ggcgugaccg ugaagggcga ccugaacggc     2820

agcgacgacg ccgacaccuu cuacuucgac gugaaggagg acggcgacgu gaccaucgag     2880

cugcccuaca gcggcagcag caacuucacc uggcuggugu acaaggaggg cgacgaccag     2940

aaccacaucg ccagcggcau cgacaagaac aacagcaagg ugggcaccuu caagagcacc     3000

aagggcagac acuacguguu caucuacaag cacgacagcg ccagcaacau cagcuacagc     3060

cugaacauca agggccuggg caacgagaag cugaaggaga aggagaacaa cgacagcagc     3120

gacaaggcca ccgugauccc caacuucaac accaccaugc agggcagccu gcugggcgac     3180

gacagcagag acuacuacag cuucgaggug aaggaggagg gcgaggugaa caucgagcug     3240

gacaagaagg acgaguucgg cgugaccugg acccugcacc ccgagagcaa caucaacgac     3300

agaaucaccu acggccaggu ggacggcaac aaggugagca acaaggugaa gcugagaccc     3360

ggcaaguacu accugcuggu guacaaguac agcggcagcg gcaacuacga gcugagagug     3420

aacaaguga                                                             3429


<210>  513
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  513
augaacuucc ugaagaucau ccugaacaga ggcaagacca ugaagagaaa gugccugagc       60

aagagacuga ugcuggccau caccauggcc accaucuuca ccgugaacag cacccugccc      120

aucuacgccg ccguggacaa gaacaacgcc accgccgccg ugcagaacga gagcaagaga      180

uacaccguga gcuaccugaa gacccugaac uacuacgacc ugguggaccu gcuggugaag      240

accgagaucg agaaccugcc cgaccuguuc caguacagca gcgacgccaa ggaguucuac      300

ggcaacaaga ccagaaugag cuucaucaug gacgagaucg gcagaagagc cccccaguac      360

accgagaucg accacaaggg cauccccacc cugguggagg uggugagagc cggcuucuac      420

cugggcuucc acaacaagga gcugaacgag aucaacaaga gaagcuucaa ggagagagug      480

auccccagca uccuggccau ccagaagaac cccaacuuca agcugggcac cgaggugcag      540

gacaagaucg ugagcgccac cggccugcug gccggcaacg agaccgcccc ccccgaggug      600

gugaacaacu ucacccccau ccugcaggac ugcaucaaga acaucgacag auacgcccug      660

gacgaccuga agagcaaggc ccuguucaac gugcuggccg cccccaccua cgacaucacc      720

gaguaccuga gagccaccaa ggagaagccc gagaacaccc ccugguacgg caagaucgac      780

ggcuucauca acgagcugaa gaagcuggcc cuguacggca agaucaacga caacaacagc      840

uggaucaucg acaacggcau cuaccacauc gccccccugg gcaagcugca cagcaacaac      900

aagaucggca ucgagacccu gaccgaggug augaaggugu accccuaccu gagcaugcag      960

caccugcaga gcgccgacca gaucaagaga cacuacgaca gcaaggacgc cgagggcaac     1020

aagauccccc uggacaaguu caagaaggag ggcaaggaga aguacugccc caagaccuac     1080

accuucgacg acggcaaggu gaucaucaag gccggcgcca gaguggagga ggagaaggug     1140

aagagacugu acugggccag caaggaggug aacagccagu ucuucagagu guacggcauc     1200

gacaagcccc uggaggaggg caaccccgac gacauccuga ccauggugau cuacaacagc     1260

cccgaggagu acaagcugaa cagcgugcug uacggcuacg acaccaacaa cggcggcaug     1320

uacaucgagc ccgagggcac cuucuucacc uacgagagag aggcccagga gagcaccuac     1380

acccuggagg agcuguucag acacgaguac acccacuacc ugcagggcag auacgccgug     1440

cccggccagu ggggcagaac caagcuguac gacaacgaca gacugaccug guacgaggag     1500

ggcggcgccg agcuguucgc cggcagcacc agaaccagcg gcauccugcc cagaaagagc     1560

aucgugagca acauccacaa caccaccaga aacaacagau acaagcugag cgacaccgug     1620

cacagcaagu acggcgccag cuucgaguuc uacaacuacg ccugcauguu cauggacuac     1680

auguacaaca aggacauggg cauccugaac aagcugaacg accuggccaa gaacaacgac     1740

guggacggcu acgacaacua caucagagac cugagcagca acuacgcccu gaacgacaag     1800

uaccaggacc acaugcagga gagaaucgac aacuacgaga accugaccgu gcccuucgug     1860

gccgacgacu accuggugag acacgccuac aagaacccca acgagaucua cagcgagauc     1920

agcgaggugg ccaagcugaa ggacgccaag agcgagguga agaagagcca guacuucagc     1980

accuucaccc ugagaggcag cuacaccggc ggcgccagca agggcaagcu ggaggaccag     2040

aaggccauga acaaguucau cgacgacagc cugaagaagc uggacaccua cagcuggagc     2100

ggcuacaaga cccugaccgc cuacuucacc aacuacaagg uggacagcag caacagagug     2160

accuacgacg ugguguucca cggcuaccug cccaacgagg gcgacagcaa gaacagccug     2220

cccuacggca agaucaacgg caccuacaag ggcaccgaga aggagaagau caaguucagc     2280

agcgagggca gcuucgaccc cgacggcaag aucgugagcu acgaguggga cuucggcgac     2340

ggcaacaaga gcaacgagga gaaccccgag cacagcuacg acaagguggg caccuacacc     2400

gugaagcuga aggugaccga cgacaagggc gagagcagcg ugagcaccac caccgccgag     2460

aucaaggacc ugagcgagaa caagcugccc gugaucuaca ugcacgugcc caagagcggc     2520

gcccugaacc agaagguggu guucuacggc aagggcaccu acgaccccga cggcagcauc     2580

gccggcuacc agugggacuu cggcgacggc agcgacuuca gcagcgagca gaaccccagc     2640

cacguguaca ccaagaaggg cgaguacacc gugacccuga gagugaugga cagcagcggc     2700

cagaugagcg agaagaccau gaagaucaag aucaccgacc ccguguaccc caucggcacc     2760

gagaaggagc ccaacaacag caaggagacc gccagcggcc ccaucgugcc cggcaucccc     2820

gugagcggca ccaucgagaa caccagcgac caggacuacu ucuacuucga cgugaucacc     2880

cccggcgagg ugaagaucga caucaacaag cugggcuacg gcggcgccac cuggguggug     2940

uacgacgaga acaacaacgc cgugagcuac gccaccgacg acggccagaa ccugagcggc     3000

aaguucaagg ccgacaagcc cggcagauac uacauccacc uguacauguu caacggcagc     3060

uacaugcccu acagaaucaa caucgagggc agcgugggca gauga                     3105


<210>  514
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  514
augaagagaa agugccugag caagagacug augcuggcca ucaccauggc caccaucuuc       60

accgugaaca gcacccugcc caucuacgcc gccguggaca agaacaacgc caccgccgcc      120

gugcagaacg agagcaagag auacaccgug agcuaccuga agacccugaa cuacuacgac      180

cugguggacc ugcuggugaa gaccgagauc gagaaccugc ccgaccuguu ccaguacagc      240

agcgacgcca aggaguucua cggcaacaag accagaauga gcuucaucau ggacgagauc      300

ggcagaagag ccccccagua caccgagauc gaccacaagg gcauccccac ccugguggag      360

guggugagag ccggcuucua ccugggcuuc cacaacaagg agcugaacga gaucaacaag      420

agaagcuuca aggagagagu gauccccagc auccuggcca uccagaagaa ccccaacuuc      480

aagcugggca ccgaggugca ggacaagauc gugagcgcca ccggccugcu ggccggcaac      540

gagaccgccc cccccgaggu ggugaacaac uucaccccca uccugcagga cugcaucaag      600

aacaucgaca gauacgcccu ggacgaccug aagagcaagg cccuguucaa cgugcuggcc      660

gcccccaccu acgacaucac cgaguaccug agagccacca aggagaagcc cgagaacacc      720

cccugguacg gcaagaucga cggcuucauc aacgagcuga agaagcuggc ccuguacggc      780

aagaucaacg acaacaacag cuggaucauc gacaacggca ucuaccacau cgccccccug      840

ggcaagcugc acagcaacaa caagaucggc aucgagaccc ugaccgaggu gaugaaggug      900

uaccccuacc ugagcaugca gcaccugcag agcgccgacc agaucaagag acacuacgac      960

agcaaggacg ccgagggcaa caagaucccc cuggacaagu ucaagaagga gggcaaggag     1020

aaguacugcc ccaagaccua caccuucgac gacggcaagg ugaucaucaa ggccggcgcc     1080

agaguggagg aggagaaggu gaagagacug uacugggcca gcaaggaggu gaacagccag     1140

uucuucagag uguacggcau cgacaagccc cuggaggagg gcaaccccga cgacauccug     1200

accaugguga ucuacaacag ccccgaggag uacaagcuga acagcgugcu guacggcuac     1260

gacaccaaca acggcggcau guacaucgag cccgagggca ccuucuucac cuacgagaga     1320

gaggcccagg agagcaccua cacccuggag gagcuguuca gacacgagua cacccacuac     1380

cugcagggca gauacgccgu gcccggccag uggggcagaa ccaagcugua cgacaacgac     1440

agacugaccu gguacgagga gggcggcgcc gagcuguucg ccggcagcac cagaaccagc     1500

ggcauccugc ccagaaagag caucgugagc aacauccaca acaccaccag aaacaacaga     1560

uacaagcuga gcgacaccgu gcacagcaag uacggcgcca gcuucgaguu cuacaacuac     1620

gccugcaugu ucauggacua cauguacaac aaggacaugg gcauccugaa caagcugaac     1680

gaccuggcca agaacaacga cguggacggc uacgacaacu acaucagaga ccugagcagc     1740

aacuacgccc ugaacgacaa guaccaggac cacaugcagg agagaaucga caacuacgag     1800

aaccugaccg ugcccuucgu ggccgacgac uaccugguga gacacgccua caagaacccc     1860

aacgagaucu acagcgagau cagcgaggug gccaagcuga aggacgccaa gagcgaggug     1920

aagaagagcc aguacuucag caccuucacc cugagaggca gcuacaccgg cggcgccagc     1980

aagggcaagc uggaggacca gaaggccaug aacaaguuca ucgacgacag ccugaagaag     2040

cuggacaccu acagcuggag cggcuacaag acccugaccg ccuacuucac caacuacaag     2100

guggacagca gcaacagagu gaccuacgac gugguguucc acggcuaccu gcccaacgag     2160

ggcgacagca agaacagccu gcccuacggc aagaucaacg gcaccuacaa gggcaccgag     2220

aaggagaaga ucaaguucag cagcgagggc agcuucgacc ccgacggcaa gaucgugagc     2280

uacgaguggg acuucggcga cggcaacaag agcaacgagg agaaccccga gcacagcuac     2340

gacaaggugg gcaccuacac cgugaagcug aaggugaccg acgacaaggg cgagagcagc     2400

gugagcacca ccaccgccga gaucaaggac cugagcgaga acaagcugcc cgugaucuac     2460

augcacgugc ccaagagcgg cgcccugaac cagaaggugg uguucuacgg caagggcacc     2520

uacgaccccg acggcagcau cgccggcuac cagugggacu ucggcgacgg cagcgacuuc     2580

agcagcgagc agaaccccag ccacguguac accaagaagg gcgaguacac cgugacccug     2640

agagugaugg acagcagcgg ccagaugagc gagaagacca ugaagaucaa gaucaccgac     2700

cccguguacc ccaucggcac cgagaaggag cccaacaaca gcaaggagac cgccagcggc     2760

cccaucgugc ccggcauccc cgugagcggc accaucgaga acaccagcga ccaggacuac     2820

uucuacuucg acgugaucac ccccggcgag gugaagaucg acaucaacaa gcugggcuac     2880

ggcggcgcca ccuggguggu guacgacgag aacaacaacg ccgugagcua cgccaccgac     2940

gacggccaga accugagcgg caaguucaag gccgacaagc ccggcagaua cuacauccac     3000

cuguacaugu ucaacggcag cuacaugccc uacagaauca acaucgaggg cagcgugggc     3060

agauga                                                                3066


<210>  515
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  515
augaaguggg ugaccuucau cagccugcug uuccuguuca gcagcgccua cagcgugcag       60

aacgagagca agagauacac cgugagcuac cugaagaccc ugaacuacua cgaccuggug      120

gaccugcugg ugaagaccga gaucgagaac cugcccgacc uguuccagua cagcagcgac      180

gccaaggagu ucuacggcaa caagaccaga augagcuuca ucauggacga gaucggcaga      240

agagcccccc aguacaccga gaucgaccac aagggcaucc ccacccuggu ggagguggug      300

agagccggcu ucuaccuggg cuuccacaac aaggagcuga acgagaucaa caagagaagc      360

uucaaggaga gagugauccc cagcauccug gccauccaga agaaccccaa cuucaagcug      420

ggcaccgagg ugcaggacaa gaucgugagc gccaccggcc ugcuggccgg caacgagacc      480

gccccccccg agguggugaa caacuucacc cccauccugc aggacugcau caagaacauc      540

gacagauacg cccuggacga ccugaagagc aaggcccugu ucaacgugcu ggccgccccc      600

accuacgaca ucaccgagua ccugagagcc accaaggaga agcccgagaa cacccccugg      660

uacggcaaga ucgacggcuu caucaacgag cugaagaagc uggcccugua cggcaagauc      720

aacgacaaca acagcuggau caucgacaac ggcaucuacc acaucgcccc ccugggcaag      780

cugcacagca acaacaagau cggcaucgag acccugaccg aggugaugaa gguguacccc      840

uaccugagca ugcagcaccu gcagagcgcc gaccagauca agagacacua cgacagcaag      900

gacgccgagg gcaacaagau cccccuggac aaguucaaga aggagggcaa ggagaaguac      960

ugccccaaga ccuacaccuu cgacgacggc aaggugauca ucaaggccgg cgccagagug     1020

gaggaggaga aggugaagag acuguacugg gccagcaagg aggugaacag ccaguucuuc     1080

agaguguacg gcaucgacaa gccccuggag gagggcaacc ccgacgacau ccugaccaug     1140

gugaucuaca acagccccga ggaguacaag cugaacagcg ugcuguacgg cuacgacacc     1200

aacaacggcg gcauguacau cgagcccgag ggcaccuucu ucaccuacga gagagaggcc     1260

caggagagca ccuacacccu ggaggagcug uucagacacg aguacaccca cuaccugcag     1320

ggcagauacg ccgugcccgg ccaguggggc agaaccaagc uguacgacaa cgacagacug     1380

accugguacg aggagggcgg cgccgagcug uucgccggca gcaccagaac cagcggcauc     1440

cugcccagaa agagcaucgu gagcaacauc cacaacacca ccagaaacaa cagauacaag     1500

cugagcgaca ccgugcacag caaguacggc gccagcuucg aguucuacaa cuacgccugc     1560

auguucaugg acuacaugua caacaaggac augggcaucc ugaacaagcu gaacgaccug     1620

gccaagaaca acgacgugga cggcuacgac aacuacauca gagaccugag cagcaacuac     1680

gcccugaacg acaaguacca ggaccacaug caggagagaa ucgacaacua cgagaaccug     1740

accgugcccu ucguggccga cgacuaccug gugagacacg ccuacaagaa ccccaacgag     1800

aucuacagcg agaucagcga gguggccaag cugaaggacg ccaagagcga ggugaagaag     1860

agccaguacu ucagcaccuu cacccugaga ggcagcuaca ccggcggcgc cagcaagggc     1920

aagcuggagg accagaaggc caugaacaag uucaucgacg acagccugaa gaagcuggac     1980

accuacagcu ggagcggcua caagacccug accgccuacu ucaccaacua caagguggac     2040

agcagcaaca gagugaccua cgacguggug uuccacggcu accugcccaa cgagggcgac     2100

agcaagaaca gccugcccua cggcaagauc aacggcaccu acaagggcac cgagaaggag     2160

aagaucaagu ucagcagcga gggcagcuuc gaccccgacg gcaagaucgu gagcuacgag     2220

ugggacuucg gcgacggcaa caagagcaac gaggagaacc ccgagcacag cuacgacaag     2280

gugggcaccu acaccgugaa gcugaaggug accgacgaca agggcgagag cagcgugagc     2340

accaccaccg ccgagaucaa ggaccugagc gagaacaagc ugcccgugau cuacaugcac     2400

gugcccaaga gcggcgcccu gaaccagaag gugguguucu acggcaaggg caccuacgac     2460

cccgacggca gcaucgccgg cuaccagugg gacuucggcg acggcagcga cuucagcagc     2520

gagcagaacc ccagccacgu guacaccaag aagggcgagu acaccgugac ccugagagug     2580

auggacagca gcggccagau gagcgagaag accaugaaga ucaagaucac cgaccccgug     2640

uaccccaucg gcaccgagaa ggagcccaac aacagcaagg agaccgccag cggccccauc     2700

gugcccggca uccccgugag cggcaccauc gagaacacca gcgaccagga cuacuucuac     2760

uucgacguga ucacccccgg cgaggugaag aucgacauca acaagcuggg cuacggcggc     2820

gccaccuggg ugguguacga cgagaacaac aacgccguga gcuacgccac cgacgacggc     2880

cagaaccuga gcggcaaguu caaggccgac aagcccggca gauacuacau ccaccuguac     2940

auguucaacg gcagcuacau gcccuacaga aucaacaucg agggcagcgu gggcagauga     3000


<210>  516
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  516
augaaguggg ugaccuucau cagccugcug uuccuguuca gcagcgccua cagcaugaag       60

agaaagugcc ugagcaagag acugaugcug gccaucacca uggccaccau cuucaccgug      120

aacagcaccc ugcccaucua cgccgccgug gacaagaaca acgccaccgc cgccagaaga      180

agaagaaaga gagugcagaa cgagagcaag agauacaccg ugagcuaccu gaagacccug      240

aacuacuacg accuggugga ccugcuggug aagaccgaga ucgagaaccu gcccgaccug      300

uuccaguaca gcagcgacgc caaggaguuc uacggcaaca agaccagaau gagcuucauc      360

auggacgaga ucggcagaag agccccccag uacaccgaga ucgaccacaa gggcaucccc      420

acccuggugg agguggugag agccggcuuc uaccugggcu uccacaacaa ggagcugaac      480

gagaucaaca agagaagcuu caaggagaga gugaucccca gcauccuggc cauccagaag      540

aaccccaacu ucaagcuggg caccgaggug caggacaaga ucgugagcgc caccggccug      600

cuggccggca acgagaccgc cccccccgag guggugaaca acuucacccc cauccugcag      660

gacugcauca agaacaucga cagauacgcc cuggacgacc ugaagagcaa ggcccuguuc      720

aacgugcugg ccgcccccac cuacgacauc accgaguacc ugagagccac caaggagaag      780

cccgagaaca cccccuggua cggcaagauc gacggcuuca ucaacgagcu gaagaagcug      840

gcccuguacg gcaagaucaa cgacaacaac agcuggauca ucgacaacgg caucuaccac      900

aucgcccccc ugggcaagcu gcacagcaac aacaagaucg gcaucgagac ccugaccgag      960

gugaugaagg uguaccccua ccugagcaug cagcaccugc agagcgccga ccagaucaag     1020

agacacuacg acagcaagga cgccgagggc aacaagaucc cccuggacaa guucaagaag     1080

gagggcaagg agaaguacug ccccaagacc uacaccuucg acgacggcaa ggugaucauc     1140

aaggccggcg ccagagugga ggaggagaag gugaagagac uguacugggc cagcaaggag     1200

gugaacagcc aguucuucag aguguacggc aucgacaagc cccuggagga gggcaacccc     1260

gacgacaucc ugaccauggu gaucuacaac agccccgagg aguacaagcu gaacagcgug     1320

cuguacggcu acgacaccaa caacggcggc auguacaucg agcccgaggg caccuucuuc     1380

accuacgaga gagaggccca ggagagcacc uacacccugg aggagcuguu cagacacgag     1440

uacacccacu accugcaggg cagauacgcc gugcccggcc aguggggcag aaccaagcug     1500

uacgacaacg acagacugac cugguacgag gagggcggcg ccgagcuguu cgccggcagc     1560

accagaacca gcggcauccu gcccagaaag agcaucguga gcaacaucca caacaccacc     1620

agaaacaaca gauacaagcu gagcgacacc gugcacagca aguacggcgc cagcuucgag     1680

uucuacaacu acgccugcau guucauggac uacauguaca acaaggacau gggcauccug     1740

aacaagcuga acgaccuggc caagaacaac gacguggacg gcuacgacaa cuacaucaga     1800

gaccugagca gcaacuacgc ccugaacgac aaguaccagg accacaugca ggagagaauc     1860

gacaacuacg agaaccugac cgugcccuuc guggccgacg acuaccuggu gagacacgcc     1920

uacaagaacc ccaacgagau cuacagcgag aucagcgagg uggccaagcu gaaggacgcc     1980

aagagcgagg ugaagaagag ccaguacuuc agcaccuuca cccugagagg cagcuacacc     2040

ggcggcgcca gcaagggcaa gcuggaggac cagaaggcca ugaacaaguu caucgacgac     2100

agccugaaga agcuggacac cuacagcugg agcggcuaca agacccugac cgccuacuuc     2160

accaacuaca agguggacag cagcaacaga gugaccuacg acgugguguu ccacggcuac     2220

cugcccaacg agggcgacag caagaacagc cugcccuacg gcaagaucaa cggcaccuac     2280

aagggcaccg agaaggagaa gaucaaguuc agcagcgagg gcagcuucga ccccgacggc     2340

aagaucguga gcuacgagug ggacuucggc gacggcaaca agagcaacga ggagaacccc     2400

gagcacagcu acgacaaggu gggcaccuac accgugaagc ugaaggugac cgacgacaag     2460

ggcgagagca gcgugagcac caccaccgcc gagaucaagg accugagcga gaacaagcug     2520

cccgugaucu acaugcacgu gcccaagagc ggcgcccuga accagaaggu gguguucuac     2580

ggcaagggca ccuacgaccc cgacggcagc aucgccggcu accaguggga cuucggcgac     2640

ggcagcgacu ucagcagcga gcagaacccc agccacgugu acaccaagaa gggcgaguac     2700

accgugaccc ugagagugau ggacagcagc ggccagauga gcgagaagac caugaagauc     2760

aagaucaccg accccgugua ccccaucggc accgagaagg agcccaacaa cagcaaggag     2820

accgccagcg gccccaucgu gcccggcauc cccgugagcg gcaccaucga gaacaccagc     2880

gaccaggacu acuucuacuu cgacgugauc acccccggcg aggugaagau cgacaucaac     2940

aagcugggcu acggcggcgc caccugggug guguacgacg agaacaacaa cgccgugagc     3000

uacgccaccg acgacggcca gaaccugagc ggcaaguuca aggccgacaa gcccggcaga     3060

uacuacaucc accuguacau guucaacggc agcuacaugc ccuacagaau caacaucgag     3120

ggcagcgugg gcagauga                                                   3138


<210>  517
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  517
augggcaccu ggauccuguu cgccugccug cugggcgccg ccuucgccau gccccugccc       60

ccccaccccg gccaccccgg cuacaucaac uucagcuacg aggugcugac cccccugaag      120

ugguaccaga gcaucagacc ccccuacccc agcuacggcu acgagcccau gggcggcugg      180

cugcaccacc agaucauccc cgugcugagc cagcagcacc cccccaccca cacccugcag      240

ccccaccacc acauccccgu ggugcccgcc cagcagcccg ugauccccca gcagcccaug      300

augcccgugc ccggccagca cagcaugacc cccauccagc accaccagcc caaccugccc      360

ccccccgccc agcagcccua ccagccccag cccgugcagc cccagcccca ccagcccaug      420

cagccccagc cccccgugca ccccaugcag ccccugcccc cccagccccc ccugcccccc      480

auguucccca ugcagccccu gccccccaug cugcccgacc ugacccugga ggccuggccc      540

agcaccgaca agaccaagag agaggaggug gacuga                                576


<210>  518
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  518
augccccugc ccccccaccc cggccacccc ggcuacauca acuucagcua cgaggugcug       60

accccccuga agugguacca gagcaucaga ccccccuacc ccagcuacgg cuacgagccc      120

augggcggcu gguga                                                       135


<210>  519
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  519
augccccugc ccccccaccc cggccacccc ggcuacauca acuucagcua cgaggugcug       60

accccccuga agugguacca gagcaucaga ccccccccca ugcugcccga ccugacccug      120

gaggccuggc ccagcaccga caagaccaag agagaggagg uggacuga                   168


<210>  520
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  520
auggccguga uggcccccag aacccuggug cugcugcuga gcggcgcccu ggcccugacc       60

cagaccuggg ccaugccccu gcccccccac cccggccacc ccggcuacau caacuucagc      120

uacgaggugc ugaccccccu gaagugguac cagagcauca gaccccccua ccccagcuac      180

ggcuacgagc ccaugggcgg cugguga                                          207


<210>  521
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  521
auggccguga uggcccccag aacccuggug cugcugcuga gcggcgcccu ggcccugacc       60

cagaccuggg ccaugccccu gcccccccac cccggccacc ccggcuacau caacuucagc      120

uacgaggugc ugaccccccu gaagugguac cagagcauca gacccccccc caugcugccc      180

gaccugaccc uggaggccug gcccagcacc gacaagacca agagagagga gguggacuga      240


<210>  522
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  522
augggcaccu ggauccuguu cgccugccug gugggcgccg ccuucgccau gccccugccc       60

ccccaccccg gccaccccgg cuacaucaac uucagcuacg aggugcugac cccccugaag      120

ugguaccaga gcaugaucag accccccuac agcagcuacg gcuacgagcc caugggcggc      180

uggcugcacc accagaucau ccccguggug agccagcagc acccccugac ccacacccug      240

cagagccacc accacauccc cguggugccc gcccagcagc ccagagugag acagcaggcc      300

cugaugcccg ugcccggcca gcagagcaug acccccaccc agcaccacca gcccaaccug      360

ccccugcccg cccagcagcc cuuccagccc cagcccgugc agccccagcc ccaccagccc      420

augcagcccc agccccccgu gcagcccaug cagccccugc ugccccagcc cccccugccc      480

cccauguucc cccugagacc ccugcccccc auccugcccg accugcaccu ggaggccugg      540

cccgccaccg acaagaccaa gcaggaggag guggacuga                             579


<210>  523
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  523
augccccugc ccccccaccc cggccacccc ggcuacauca acuucagcua cgaggugcug       60

accccccuga agugguacca gagcaugauc agaccccccu acagcagcua cggcuacgag      120

cccaugggcg gcugguga                                                    138


<210>  524
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  524
augccccugc ccccccaccc cggccacccc ggcuacauca acuucagcua cgaggugcug       60

accccccuga agugguacca gagcaugauc agaccccccc ccauccugcc cgaccugcac      120

cuggaggccu ggcccgccac cgacaagacc aagcaggagg agguggacug a               171


<210>  525
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  525
auggccguga uggcccccag aacccuggug cugcugcuga gcggcgcccu ggcccugacc       60

cagaccuggg ccaugccccu gcccccccac cccggccacc ccggcuacau caacuucagc      120

uacgaggugc ugaccccccu gaagugguac cagagcauga ucagaccccc cuacagcagc      180

uacggcuacg agcccauggg cggcugguga                                       210


<210>  526
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  526
auggccguga uggcccccag aacccuggug cugcugcuga gcggcgcccu ggcccugacc       60

cagaccuggg ccaugccccu gcccccccac cccggccacc ccggcuacau caacuucagc      120

uacgaggugc ugaccccccu gaagugguac cagagcauga ucagaccccc ccccauccug      180

cccgaccugc accuggaggc cuggcccgcc accgacaaga ccaagcagga ggagguggac      240

uga                                                                    243


<210>  527
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  527
augggcaccu ggauccuguu cgccugccug cugggcgccg ccuucagcau gccccugccc       60

ccccaccccg gccaccccgg cuacaucaac uucagcuacg aggugcugac cccccugaag      120

ugguaccaga acaugaucag acaccccuac accagcuacg gcuacgagcc caugggcggc      180

uggcugcacc accagaucau ccccguggug agccagcaga ccccccagag ccacgcccug      240

cagccccacc accacauccc cauggugccc gcccagcagc ccggcauccc ccagcagccc      300

augaugcccc ugcccggcca gcacagcaug acccccaccc agcaccacca gcccaaccug      360

ccccugcccg cccagcagcc cuuccagccc cagcccgugc agccccagcc ccaccagccc      420

cugcagcccc agagccccau gcaccccauc cagccccugc ugccccagcc cccccugccc      480

cccauguuca gcaugcagag ccugcugccc gaccugcccc uggaggccug gcccgccacc      540

gacaagacca agagagagga gguggacuga                                       570


<210>  528
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  528
augccccugc ccccccaccc cggccacccc ggcuacauca acuucagcua cgaggugcug       60

accccccuga agugguacca gaacaugauc agacaccccu acaccagcua cggcuacgag      120

cccaugggcg gcugguga                                                    138


<210>  529
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  529
augccccugc ccccccaccc cggccacccc ggcuacauca acuucagcua cgaggugcug       60

accccccuga agugguacca gaacaugauc agacacccca gccugcugcc cgaccugccc      120

cuggaggccu ggcccgccac cgacaagacc aagagagagg agguggacug a               171


<210>  530
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  530
auggccguga uggcccccag aacccuggug cugcugcuga gcggcgcccu ggcccugacc       60

cagaccuggg ccaugccccu gcccccccac cccggccacc ccggcuacau caacuucagc      120

uacgaggugc ugaccccccu gaagugguac cagaacauga ucagacaccc cuacaccagc      180

uacggcuacg agcccauggg cggcugguga                                       210


<210>  531
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  531
auggccguga uggcccccag aacccuggug cugcugcuga gcggcgcccu ggcccugacc       60

cagaccuggg ccaugccccu gcccccccac cccggccacc ccggcuacau caacuucagc      120

uacgaggugc ugaccccccu gaagugguac cagaacauga ucagacaccc cagccugcug      180

cccgaccugc cccuggaggc cuggcccgcc accgacaaga ccaagagaga ggagguggac      240

uga                                                                    243


<210>  532
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  532
augggcaccu ggauccuguu cgccugccug cugggcgccg ccuucagcau gccccugccc       60

ccccaccccg gccaccccgg cuacaucaac uucagcuaca ucagacaccc cuacaccagc      120

uacggcuacg agcccauggg cggcuggcug caccaccaga ucauccccgu ggugagccag      180

cagacccccc agagccacgc ccugcagccc caccaccaca uccccauggu gcccgcccag      240

cagcccggca ucccccagca gcccaugaug ccccugcccg gccagcacag caugaccccc      300

acccagcacc accagcccaa ccugccccug cccgcccagc agcccuucca gccccagccc      360

gugcagcccc agccccacca gccccugcag ccccagagcc ccaugcaccc cauccagccc      420

cugcugcccc agcccccccu gccccccaug uucagcaugc agagccugcu gcccgaccug      480

ccccuggagg ccuggcccgc caccgacaag accaagagag aggaggugga cuga            534


<210>  533
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  533
augggcaccu ggaucuucuu cgccugccug cugggcgcca gccuggccau gccccugccc       60

ccccaccccg gccaccccgg cuacaucaac uucagcuacg aggugcugac cccccugaag      120

ugguaccaga acaugaucag acaccccuac accagcuacg gcuacgagcc caugggcggc      180

uggcugcacc accagaucau ccccguggug agccagcaga ccccccagag ccacgcccug      240

cagccccacc accacauccc cauggugccc gcccagcagc ccggcauccc ccagcagccc      300

augaugcccc ugcccggcca gcacagcaug acccccaccc agcaccacca gcccaaccug      360

ccccugcccg cccagcagcc cuuccagccc cagcccgugc agccccagcc ccaccagccc      420

cugcagcccc agagccccau gcaccccauc cagccccugc ugccccagcc cccccugccc      480

cccauguuca gcaugcagag ccugcugccc gaccugcccc uggaggccug gcccgccacc      540

gacaagacca agagagagga gguggacuga                                       570


<210>  534
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  534
augggcaccu ggauccuguu cgccugccug cugggcgccg ccuucagcau gccccugccc       60

ccccaccccg gccaccccgg cuacaucaac uucagcuacg aggugcugac cccccugaag      120

ugguaccaga acaugaucag acaccccagc cugcugcccg accugccccu ggaggccugg      180

cccgccaccg acaagaccaa gagagaggag guggacuga                             219


<210>  535
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  535
augggcaccu ggauccuguu cgccugccug cugggcgccg ccuucagcau gccccugccc       60

ccccaccccg gccaccccgg cuacaucaac uucagcuacg aggaccugua ccuggaggcc      120

aucagaaucg acagaaccgc cuucgugcug accccccuga agugguacca gaacaugauc      180

agacaccccu acaccagcua cggcuacgag cccaugggcg gcuggcugca ccaccagauc      240

auccccgugg ugagccagca gaccccccag agccacgccc ugcagcccca ccaccacauc      300

cccauggugc ccgcccagca gcccggcauc ccccagcagc ccaugaugcc ccugcccggc      360

cagcacagca ugacccccac ccagcaccac cagcccaacc ugccccugcc cgcccagcag      420

cccuuccagc cccagcccgu gcagccccag ccccaccagc cccugcagcc ccagagcccc      480

augcacccca uccagccccu gcugccccag cccccccugc cccccauguu cagcaugcag      540

agccugcugc ccgaccugcc ccuggaggcc uggcccgcca ccgacaagac caagagagag      600

gagguggacu ga                                                          612


<210>  536
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  536
augggcaccu ggauccuguu cgccugccug cugggcgccg ccuucagcau gccccugccc       60

ccccaccccg gccaccccgg cuacaucaac uucagcuacg aggugcugac cccccugaag      120

ugguaccaga acaugaucag acaccccacc ccccagagcc acgcccugca gccccaccac      180

cacaucccca uggugcccgc ccagcagccc ggcauccccc agcagcccau gaugccccug      240

cccggccagc acagcaugac ccccacccag caccaccagc ccaaccugcc ccugcccgcc      300

cagcagcccu uccagcccca gcccgugcag ccccagcccc accagccccu gcagccccag      360

agccccaugc accccaucca gccccugcug ccccagcccc cccugccccc cauguucagc      420

augcagagcc ugcugcccga ccugccccug gaggccuggc ccgccaccga caagaccaag      480

agagaggagg uggacuga                                                    498


<210>  537
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  537
augccccugc ccccccaccc cggccacccc ggcuacauca acuucagcua cgaggugcug       60

accccccuga agugguacca gaacaugauc agacaccccu acaccagcua cggcuacgag      120

cccaugggcg gcuggcugca ccaccagauc auccccgugg ugagccagca gaccccccag      180

agccacgccc ugcagcccca ccaccacauc cccauggugc ccgcccagca gcccggcauc      240

ccccagcagc ccaugaugcc ccugcccggc cagcacagca ugacccccac ccagcaccac      300

cagcccaacc ugccccugcc cgcccagcag cccuuccagc cccagcccgu gcagccccag      360

ccccaccagc cccugcagcc ccagagcccc augcacccca uccagccccu gcugccccag      420

cccccccugc cccccauguu cagcaugcag agccugcugc ccgaccugcc ccuggaggcc      480

uggcccgcca ccgacaagac caagagagag gagguggacu ga                         522


<210>  538
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  538
augcccggcg uggccagacu gccccugcug cugggccugc ugcugcugcc cagacccggc       60

agaccccugg accuggccga cuacaccuac gaccuggccg aggaggacga cagcgagccc      120

cugaacuaca aggaccccug caaggccgcc gccuuccugg gcgacaucgc ccuggacgag      180

gaggaccuga gagccuucca ggugcagcag gccguggacc ugagaagaca caccgccaga      240

aagagcagca ucaaggccgc cgugcccggc aacaccagca cccccagcug ccagagcacc      300

aacggccagc cccagagagg cgccugcggc agauggagag gcagaagcag aagcagaaga      360

gccgccacca gcagacccga gagagugugg cccgacggcg ugauccccuu cgugaucggc      420

ggcaacuuca ccggcagcca gagagccgug uucagacagg ccaugagaca cugggagaag      480

cacaccugcg ugaccuuccu ggagagaacc gacgaggaca gcuacaucgu guucaccuac      540

agacccugcg gcugcugcag cuacgugggc agaagaggcg gcggccccca ggccaucagc      600

aucggcaaga acugcgacaa guucggcauc guggugcacg agcugggcca cguggugggc      660

uucuggcacg agcacaccag acccgacaga gacagacacg ugagcaucgu gagagagaac      720

auccagcccg gccaggagua caacuuccug aagauggagc cccaggaggu ggagagccug      780

ggcgagaccu acgacuucga cagcaucaug cacuacgcca gaaacaccuu cagcagaggc      840

aucuuccugg acaccaucgu gcccaaguac gaggugaacg gcgugaagcc ccccaucggc      900

cagagaacca gacugagcaa gggcgacauc gcccaggcca gaaagcugua caagugcccc      960

gccugcggcg agacccugca ggacagcacc ggcaacuuca gcagccccga guaccccaac     1020

ggcuacagcg cccacaugca cugcgugugg agaaucagcg ugacccccgg cgagaagauc     1080

auccugaacu ucaccagccu ggaccuguac agaagcagac ugugcuggua cgacuacgug     1140

gaggugagag acggcuucug gagaaaggcc ccccugagag gcagauucug cggcagcaag     1200

cugcccgagc ccaucgugag caccgacagc agacuguggg uggaguucag aagcagcagc     1260

aacugggugg gcaagggcuu cuucgccgug uacgaggcca ucugcggcgg cgacgugaag     1320

aaggacuacg gccacaucca gagccccaac uaccccgacg acuacagacc cagcaaggug     1380

ugcaucugga gaauccaggu gagcgagggc uuccacgugg gccugaccuu ccagagcuuc     1440

gagaucgaga gacacgacag cugcgccuac gacuaccugg aggugagaga cggccacagc     1500

gagagcagca cccugaucgg cagauacugc ggcuacgaga agcccgacga caucaagagc     1560

accagcagca gacuguggcu gaaguucgug agcgacggca gcaucaacaa ggccggcuuc     1620

gccgugaacu ucuucaagga gguggacgag ugcagcagac ccaacagagg cggcugcgag     1680

cagagaugcc ugaacacccu gggcagcuac aagugcagcu gcgaccccgg cuacgagcug     1740

gcccccgaca agagaagaug cgaggccgcc ugcggcggcu uccugaccaa gcugaacggc     1800

agcaucacca gccccggcug gcccaaggag uaccccccca acaagaacug caucuggcag     1860

cugguggccc ccacccagua cagaaucagc cugcaguucg acuucuucga gaccgagggc     1920

aacgacgugu gcaaguacga cuucguggag gugagaagcg gccugaccgc cgacagcaag     1980

cugcacggca aguucugcgg cagcgagaag cccgagguga ucaccagcca guacaacaac     2040

augagagugg aguucaagag cgacaacacc gugagcaaga agggcuucaa ggcccacuuc     2100

uucagcgaca aggacgagug cagcaaggac aacggcggcu gccagcagga cugcgugaac     2160

accuucggca gcuacgagug ccagugcaga agcggcuucg ugcugcacga caacaagcac     2220

gacugcaagg aggccggcug cgaccacaag gugaccagca ccagcggcac caucaccagc     2280

cccaacuggc ccgacaagua ccccagcaag aaggagugca ccugggccau cagcagcacc     2340

cccggccaca gagugaagcu gaccuucaug gagauggaca ucgagagcca gcccgagugc     2400

gccuacgacc accuggaggu guucgacggc agagacgcca aggcccccgu gcugggcaga     2460

uucugcggca gcaagaagcc cgagcccgug cuggccaccg gcagcagaau guuccugaga     2520

uucuacagcg acaacagcgu gcagagaaag ggcuuccagg ccagccacgc caccgagugc     2580

ggcggccagg ugagagccga cgugaagacc aaggaccugu acagccacgc ccaguucggc     2640

gacaacaacu accccggcgg cguggacugc gaguggguga ucguggccga ggagggcuac     2700

ggcguggagc ugguguucca gaccuucgag guggaggagg agaccgacug cggcuacgac     2760

uacauggagc uguucgacgg cuacgacagc accgccccca gacugggcag auacugcggc     2820

agcggccccc ccgaggaggu guacagcgcc ggcgacagcg ugcuggugaa guuccacagc     2880

gacgacacca ucaccaagaa gggcuuccac cugagauaca ccagcaccaa guuccaggac     2940

acccugcaca gcagaaagug a                                               2961


<210>  539
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  539
augguggccg gcaccagaug ccugcuggcc cugcugcugc cccaggugcu gcugggcggc       60

gccgccggcc uggugcccga gcugggcaga agaaaguucg ccgccgccag cagcggcaga      120

cccagcagcc agcccagcga cgaggugcug agcgaguucg agcugagacu gcugagcaug      180

uucggccuga agcagagacc cacccccagc agagacgccg uggugccccc cuacaugcug      240

gaccuguaca gaagacacag cggccagccc ggcagccccg cccccgacca cagacuggag      300

agagccgcca gcagagccaa caccgugaga agcuuccacc acgaggagag ccuggaggag      360

cugcccgaga ccagcggcaa gaccaccaga agauucuucu ucaaccugag cagcaucccc      420

accgaggagu ucaucaccag cgccgagcug cagguguuca gagagcagau gcaggacgcc      480

cugggcaaca acagcagcuu ccaccacaga aucaacaucu acgagaucau caagcccgcc      540

accgccaaca gcaaguuccc cgugaccaga cugcuggaca ccagacuggu gaaccagaac      600

gccagcagau gggagagcuu cgacgugacc cccgccguga ugagauggac cgcccagggc      660

cacgccaacc acggcuucgu gguggaggug gcccaccugg aggagaagca gggcgugagc      720

aagagacacg ugagaaucag cagaagccug caccaggacg agcacagcug gagccagauc      780

agaccccugc uggugaccuu cggccacgac ggcaagggcc acccccugca caagagagag      840

aagagacagg ccaagcacaa gcagagaaag agacugaaga gcagcugcaa gagacacccc      900

cuguacgugg acuucagcga cgugggcugg aacgacugga ucguggcccc ccccggcuac      960

cacgccuucu acugccacgg cgagugcccc uucccccugg ccgaccaccu gaacagcacc     1020

aaccacgcca ucgugcagac ccuggugaac agcgugaaca gcaagauccc caaggccugc     1080

ugcgugccca ccgagcugag cgccaucagc augcuguacc uggacgagaa cgagaaggug     1140

gugcugaaga acuaccagga caugguggug gagggcugcg gcugcagaug a              1191


<210>  540
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  540
augauccccg gcaacagaau gcugauggug gugcugcugu gccaggugcu gcugggcggc       60

gccagccacg ccagccugau ccccgagacc ggcaagaaga agguggccga gauccagggc      120

cacgccggcg gcagaagaag cggccagagc cacgagcugc ugagagacuu cgaggccacc      180

cugcugcaga uguucggccu gagaagaaga ccccagccca gcaagagcgc cgugaucccc      240

gacuacauga gagaccugua cagacugcag agcggcgagg aggaggagga gcagauccac      300

agcaccggcc uggaguaccc cgagagaccc gccagcagag ccaacaccgu gagaagcuuc      360

caccacgagg agcaccugga gaacaucccc ggcaccagcg agaacagcgc cuucagauuc      420

cuguucaacc ugagcagcau ccccgagaac gaggugauca gcagcgccga gcugagacug      480

uucagagagc agguggacca gggccccgac ugggagagag gcuuccacag aaucaacauc      540

uacgagguga ugaagccccc cgccgaggug gugcccggcc accugaucac cagacugcug      600

gacaccagac uggugcacca caacgugacc agaugggaga ccuucgacgu gagccccgcc      660

gugcugagau ggaccagaga gaagcagccc aacuacggcc uggccaucga ggugacccac      720

cugcaccaga ccagaaccca ccagggccag cacgugagaa ucagcagaag ccugccccag      780

ggcagcggca acugggccca gcugagaccc cugcugguga ccuucggcca cgacggcaga      840

ggccacgccc ugaccagaag aagaagagcc aagagaagcc ccaagcacca cagccagaga      900

gccagaaaga agaacaagaa cugcagaaga cacagccugu acguggacuu cagcgacgug      960

ggcuggaacg acuggaucgu ggcccccccc ggcuaccagg ccuucuacug ccacggcgac     1020

ugccccuucc cccuggccga ccaccugaac agcaccaacc acgccaucgu gcagacccug     1080

gugaacagcg ugaacagcag cauccccaag gccugcugcg ugcccaccga gcugagcgcc     1140

aucagcaugc uguaccugga cgaguacgac aagguggugc ugaagaacua ccaggagaug     1200

gugguggagg gcugcggcug cagauga                                         1227


<210>  541
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  541
augcccggcc ugggcagaag agcccagugg cugugcuggu gguggggccu gcugugcagc       60

ugcugcggcc cccccccccu gagacccccc cugcccgccg ccgccgccgc cgccgccggc      120

ggccagcugc ugggcgacgg cggcagcccc ggcagaaccg agcagccccc ccccagcccc      180

cagagcagca gcggcuuccu guacagaaga cugaagaccc aggagaagag agagaugcag      240

aaggagaucc ugagcgugcu gggccugccc cacagaccca gaccccugca cggccugcag      300

cagccccagc cccccgcccu gagacagcag gaggagcagc agcagcagca gcagcugccc      360

agaggcgagc ccccccccgg cagacugaag agcgcccccc uguucaugcu ggaccuguac      420

aacgcccuga gcgccgacaa cgacgaggac ggcgccagcg agggcgagag acagcagagc      480

uggccccacg aggccgccag cagcagccag agaagacagc ccccccccgg cgccgcccac      540

ccccugaaca gaaagagccu gcuggccccc ggcagcggca gcggcggcgc cagcccccug      600

accagcgccc aggacagcgc cuuccugaac gacgccgaca uggugaugag cuucgugaac      660

cugguggagu acgacaagga guucagcccc agacagagac accacaagga guucaaguuc      720

aaccugagcc agauccccga gggcgaggug gugaccgccg ccgaguucag aaucuacaag      780

gacugcguga ugggcagcuu caagaaccag accuuccuga ucagcaucua ccaggugcug      840

caggagcacc agcacagaga cagcgaccug uuccugcugg acaccagagu ggugugggcc      900

agcgaggagg gcuggcugga guucgacauc accgccacca gcaaccugug gguggugacc      960

ccccagcaca acaugggccu gcagcugagc guggugacca gagacggcgu gcacgugcac     1020

cccagagccg ccggccuggu gggcagagac ggccccuacg acaagcagcc cuucauggug     1080

gccuucuuca aggugagcga ggugcacgug agaaccacca gaagcgccag cagcagaaga     1140

agacagcaga gcagaaacag aagcacccag agccaggacg uggccagagu gagcagcgcc     1200

agcgacuaca acagcagcga gcugaagacc gccugcagaa agcacgagcu guacgugagc     1260

uuccaggacc ugggcuggca ggacuggauc aucgccccca agggcuacgc cgccaacuac     1320

ugcgacggcg agugcagcuu cccccugaac gcccacauga acgccaccaa ccacgccauc     1380

gugcagaccc uggugcaccu gaugaacccc gaguacgugc ccaagcccug cugcgccccc     1440

accaagcuga acgccaucag cgugcuguac uucgacgaca acagcaacgu gauccugaag     1500

aaguacagaa acaugguggu gagagccugc ggcugccacu ga                        1542


<210>  542
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  542
augcacguga gaagccugag agccgccgcc ccccacagcu ucguggcccu gugggccccc       60

cuguuccugc ugagaagcgc ccuggccgac uucagccugg acaacgaggu gcacagcagc      120

uucauccaca gaagacugag aagccaggag agaagagaga ugcagagaga gauccugagc      180

auccugggcc ugccccacag acccagaccc caccugcagg gcaagcacaa cagcgccccc      240

auguucaugc uggaccugua caacgccaug gccguggagg agggcggcgg ccccggcggc      300

cagggcuuca gcuaccccua caaggccgug uucagcaccc agggcccccc ccuggccagc      360

cugcaggaca gccacuuccu gaccgacgcc gacaugguga ugagcuucgu gaaccuggug      420

gagcacgaca aggaguucuu ccaccccaga uaccaccaca gagaguucag auucgaccug      480

agcaagaucc ccgagggcga ggccgugacc gccgccgagu ucagaaucua caaggacuac      540

aucagagaga gauucgacaa cgagaccuuc agaaucagcg uguaccaggu gcugcaggag      600

caccugggca gagagagcga ccuguuccug cuggacagca gaacccugug ggccagcgag      660

gagggcuggc ugguguucga caucaccgcc accagcaacc acuggguggu gaaccccaga      720

cacaaccugg gccugcagcu gagcguggag acccuggacg gccagagcau caaccccaag      780

cuggccggcc ugaucggcag acacggcccc cagaacaagc agcccuucau gguggccuuc      840

uucaaggcca ccgaggugca cuucagaagc aucagaagca ccggcagcaa gcagagaagc      900

cagaacagaa gcaagacccc caagaaccag gaggcccuga gaauggccaa cguggccgag      960

aacagcagca gcgaccagag acaggccugc aagaagcacg agcuguacgu gagcuucaga     1020

gaccugggcu ggcaggacug gaucaucgcc cccgagggcu acgccgccua cuacugcgag     1080

ggcgagugcg ccuucccccu gaacagcuac augaacgcca ccaaccacgc caucgugcag     1140

acccuggugc acuucaucaa ccccgagacc gugcccaagc ccugcugcgc ccccacccag     1200

cugaacgcca ucagcgugcu guacuucgac gacagcagca acgugauccu gaagaaguac     1260

agaaacaugg uggugagagc cugcggcugc cacuga                               1296


<210>  543
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  543
augaaggcca gcgccgcccu gcugugccug cugcugaccg ccgccgccuu cagcccccag       60

ggccuggccc agcccguggg caucaacacc agcaccaccu gcugcuacag auucaucaac      120

aagaagaucc ccaagcagag acuggagagc uacagaagaa ccaccagcag ccacugcccc      180

agagaggccg ugaucuucaa gaccaagcug gacaaggaga ucugcgccga ccccacccag      240

aagugggugc aggacuucau gaagcaccug gacaagaaga cccagacccc caagcuguga      300


<210>  544
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  544
augcugcuga cccugaucau ccugcugccc guggugagca aguucagcuu cgugagccug       60

agcgcccccc agcacuggag cugccccgag ggcacccugg ccggcaacgg caacagcacc      120

ugcgugggcc ccgcccccuu ccugaucuuc agccacggca acagcaucuu cagaaucgac      180

accgagggca ccaacuacga gcagcuggug guggacgccg gcgugagcgu gaucauggac      240

uuccacuaca acgagaagag aaucuacugg guggaccugg agagacagcu gcugcagaga      300

guguuccuga acggcagcag acaggagaga gugugcaaca ucgagaagaa cgugagcggc      360

auggccauca acuggaucaa cgaggaggug aucuggagca accagcagga gggcaucauc      420

accgugaccg acaugaaggg caacaacagc cacauccugc ugagcgcccu gaaguacccc      480

gccaacgugg ccguggaccc cguggagaga uucaucuucu ggagcagcga gguggccggc      540

agccuguaca gagccgaccu ggacggcgug ggcgugaagg cccugcugga gaccagcgag      600

aagaucaccg ccgugagccu ggacgugcug gacaagagac uguucuggau ccaguacaac      660

agagagggca gcaacagccu gaucugcagc ugcgacuacg acggcggcag cgugcacauc      720

agcaagcacc ccacccagca caaccuguuc gccaugagcc uguucggcga cagaaucuuc      780

uacagcaccu ggaagaugaa gaccaucugg aucgccaaca agcacaccgg caaggacaug      840

gugagaauca accugcacag cagcuucgug ccccugggcg agcugaaggu ggugcacccc      900

cuggcccagc ccaaggccga ggacgacacc ugggagcccg agcagaagcu gugcaagcug      960

agaaagggca acugcagcag caccgugugc ggccaggacc ugcagagcca ccugugcaug     1020

ugcgccgagg gcuacgcccu gagcagagac agaaaguacu gcgaggacgu gaacgagugc     1080

gccuucugga accacggcug cacccugggc ugcaagaaca cccccggcag cuacuacugc     1140

accugccccg ugggcuucgu gcugcugccc gacggcaaga gaugccacca gcuggugagc     1200

ugccccagaa acgugagcga gugcagccac gacugcgugc ugaccagcga gggcccccug     1260

ugcuucugcc ccgagggcag cgugcuggag agagacggca agaccugcag cggcugcagc     1320

agccccgaca acggcggcug cagccagcug ugcgugcccc ugagccccgu gagcugggag     1380

ugcgacugcu uccccggcua cgaccugcag cuggacgaga agagcugcgc cgccagcggc     1440

ccccagcccu uccugcuguu cgccaacagc caggacauca gacacaugca cuucgacggc     1500

accgacuacg gcacccugcu gagccagcag augggcaugg uguacgcccu ggaccacgac     1560

cccguggaga acaagaucua cuucgcccac accgcccuga aguggaucga gagagccaac     1620

auggacggca gccagagaga gagacugauc gaggagggcg uggacgugcc cgagggccug     1680

gccguggacu ggaucggcag aagauucuac uggaccgaca gaggcaagag ccugaucggc     1740

agaagcgacc ugaacggcaa gagaagcaag aucaucacca aggagaacau cagccagccc     1800

agaggcaucg ccgugcaccc cauggccaag agacuguucu ggaccgacac cggcaucaac     1860

cccagaaucg agagcagcag ccugcagggc cugggcagac uggugaucgc cagcagcgac     1920

cugaucuggc ccagcggcau caccaucgac uuccugaccg acaagcugua cuggugcgac     1980

gccaagcaga gcgugaucga gauggccaac cuggacggca gcaagagaag aagacugacc     2040

cagaacgacg ugggccaccc cuucgccgug gccguguucg aggacuacgu gugguucagc     2100

gacugggcca ugcccagcgu gaugagagug aacaagagaa ccggcaagga cagagugaga     2160

cugcagggca gcaugcugaa gcccagcagc cugguggugg ugcacccccu ggccaagccc     2220

ggcgccgacc ccugccugua ccagaacggc ggcugcgagc acaucugcaa gaagagacug     2280

ggcaccgccu ggugcagcug cagagagggc uucaugaagg ccagcgacgg caagaccugc     2340

cuggcccugg acggccacca gcugcuggcc ggcggcgagg uggaccugaa gaaccaggug     2400

accccccugg acauccugag caagaccaga gugagcgagg acaacaucac cgagagccag     2460

cacaugcugg uggccgagau cauggugagc gaccaggacg acugcgcccc cgugggcugc     2520

agcauguacg ccagaugcau cagcgagggc gaggacgcca ccugccagug ccugaagggc     2580

uucgccggcg acggcaagcu gugcagcgac aucgacgagu gcgagauggg cgugcccgug     2640

ugcccccccg ccagcagcaa gugcaucaac accgagggcg gcuacgugug cagaugcagc     2700

gagggcuacc agggcgacgg cauccacugc cuggacaucg acgagugcca gcugggcgag     2760

cacagcugcg gcgagaacgc cagcugcacc aacaccgagg gcggcuacac cugcaugugc     2820

gccggcagac ugagcgagcc cggccugauc ugccccgaca gcaccccccc cccccaccug     2880

agagaggacg accaccacua cagcgugaga aacagcgaca gcgagugccc ccugagccac     2940

gacggcuacu gccugcacga cggcgugugc auguacaucg aggcccugga caaguacgcc     3000

ugcaacugcg uggugggcua caucggcgag agaugccagu acagagaccu gaaguggugg     3060

gagcugagac acgccggcca cggccagcag cagaagguga ucgugguggc cgugugcgug     3120

guggugcugg ugaugcugcu gcugcugagc cuguggggcg cccacuacua cagaacccag     3180

aagcugcuga gcaagaaccc caagaacccc uacgaggaga gcagcagaga cgugagaagc     3240

agaagacccg ccgacaccga ggacggcaug agcagcugcc cccagcccug guucguggug     3300

aucaaggagc accaggaccu gaagaacggc ggccagcccg uggccggcga ggacggccag     3360

gccgccgacg gcagcaugca gcccaccagc uggagacagg agccccagcu gugcggcaug     3420

ggcaccgagc agggcugcug gauccccgug agcagcgaca agggcagcug cccccaggug     3480

auggagagaa gcuuccacau gcccagcuac ggcacccaga cccuggaggg cggcguggag     3540

aagccccaca gccugcugag cgccaacccc cuguggcagc agagagcccu ggaccccccc     3600

caccagaugg agcugaccca guga                                            3624


<210>  545
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  545
augaccgccg gcagaagaau ggagaugcug ugcgccggca gagugcccgc ccugcugcug       60

ugccugggcu uccaccugcu gcaggccgug cugagcacca ccgugauccc cagcugcauc      120

cccggcgaga gcagcgacaa cugcaccgcc cuggugcaga ccgaggacaa ccccagagug      180

gcccagguga gcaucaccaa gugcagcagc gacaugaacg gcuacugccu gcacggccag      240

ugcaucuacc ugguggacau gagccagaac uacugcagau gcgagguggg cuacaccggc      300

gugagaugcg agcacuucuu ccugaccgug caccagcccc ugagcaagga guacguggcc      360

cugaccguga uccugaucau ccuguuccug aucaccgugg ugggcagcac cuacuacuuc      420

ugcagauggu acagaaacag aaagagcaag gagcccaaga aggaguacga gagagugacc      480

agcggcgacc ccgagcugcc ccagguguga                                       510


<210>  546
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  546
auggccgagg gcgagaucac caccuucacc gcccugaccg agaaguucaa ccugcccccc       60

ggcaacuaca agaagcccaa gcugcuguac ugcagcaacg gcggccacuu ccugagaauc      120

cugcccgacg gcaccgugga cggcaccaga gacagaagcg accagcacau ccagcugcag      180

cugagcgccg agagcguggg cgagguguac aucaagagca ccgagaccgg ccaguaccug      240

gccauggaca ccgacggccu gcuguacggc agccagaccc ccaacgagga gugccuguuc      300

cuggagagac uggaggagaa ccacuacaac accuacauca gcaagaagca cgccgagaag      360

aacugguucg ugggccugaa gaagaacggc agcugcaaga gaggccccag aacccacuac      420

ggccagaagg ccauccuguu ccugccccug cccgugagca gcgacuga                   468


<210>  547
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  547
auggugggcg ugggcggcgg cgacguggag gacgugaccc ccagacccgg cggcugccag       60

aucagcggca gaggcgccag aggcugcaac ggcauccccg gcgccgccgc cugggaggcc      120

gcccugccca gaagaagacc cagaagacac cccagcguga accccagaag cagagccgcc      180

ggcagcccca gaaccagagg cagaagaacc gaggagagac ccagcggcag cagacugggc      240

gacagaggca gaggcagagc ccugcccggc ggcagacugg gcggcagagg cagaggcaga      300

gcccccgaga gagugggcgg cagaggcaga ggcagaggca ccgccgcccc cagagccgcc      360

cccgccgcca gaggcagcag acccggcccc gccggcacca uggccgccgg cagcaucacc      420

acccugcccg cccugcccga ggacggcggc agcggcgccu ucccccccgg ccacuucaag      480

gaccccaaga gacuguacug caagaacggc ggcuucuucc ugagaaucca ccccgacggc      540

agaguggacg gcgugagaga gaagagcgac ccccacauca agcugcagcu gcaggccgag      600

gagagaggcg uggugagcau caagggcgug ugcgccaaca gauaccuggc caugaaggag      660

gacggcagac ugcuggccag caagugcgug accgacgagu gcuucuucuu cgagagacug      720

gagagcaaca acuacaacac cuacagaagc agaaaguaca ccagcuggua cguggcccug      780

aagagaaccg gccaguacaa gcugggcagc aagaccggcc ccggccagaa ggccauccug      840

uuccugccca ugagcgccaa gagcuga                                          867


<210>  548
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  548
augcacaagu ggauccugac cuggauccug cccacccugc uguacagaag cugcuuccac       60

aucaucugcc uggugggcac caucagccug gccugcaacg acaugacccc cgagcagaug      120

gccaccaacg ugaacugcag cagccccgag agacacacca gaagcuacga cuacauggag      180

ggcggcgaca ucagagugag aagacuguuc ugcagaaccc agugguaccu gagaaucgac      240

aagagaggca aggugaaggg cacccaggag augaagaaca acuacaacau cauggagauc      300

agaaccgugg ccgugggcau cguggccauc aagggcgugg agagcgaguu cuaccuggcc      360

augaacaagg agggcaagcu guacgccaag aaggagugca acgaggacug caacuucaag      420

gagcugaucc uggagaacca cuacaacacc uacgccagcg ccaaguggac ccacaacggc      480

ggcgagaugu ucguggcccu gaaccagaag ggcauccccg ugagaggcaa gaagaccaag      540

aaggagcaga agaccgccca cuuccugccc auggccauca ccuga                      585


<210>  549
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  549
augaagcugc ugcccagcgu ggugcugaag cuguuccugg ccgccgugcu gagcgcccug       60

gugaccggcg agagccugga gagacugaga agaggccugg ccgccggcac cagcaacccc      120

gaccccccca ccgugagcac cgaccagcug cugccccugg gcggcggcag agacagaaag      180

gugagagacc ugcaggaggc cgaccuggac cugcugagag ugacccugag cagcaagccc      240

caggcccugg ccacccccaa caaggaggag cacggcaaga gaaagaagaa gggcaagggc      300

cugggcaaga agagagaccc cugccugaga aaguacaagg acuucugcau ccacggcgag      360

ugcaaguacg ugaaggagcu gagagccccc agcugcaucu gccaccccgg cuaccacggc      420

gagagaugcc acggccugag ccugcccgug gagaacagac uguacaccua cgaccacacc      480

accauccugg ccgugguggc cguggugcug agcagcgugu gccugcuggu gaucgugggc      540

cugcugaugu ucagauacca cagaagaggc ggcuacgacg uggagaacga ggagaaggug      600

aagcugggca ugaccaacag ccacuga                                          627


<210>  550
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  550
auguggguga ccaagcugcu gcccgcccug cugcugcagc acgugcugcu gcaccugcug       60

cugcugccca ucgccauccc cuacgccgag ggccagagaa agagaagaaa caccauccac      120

gaguucaaga agagcgccaa gaccacccug aucaagaucg accccgcccu gaagaucaag      180

accaagaagg ugaacaccgc cgaccagugc gccaacagau gcaccagaaa caagggccug      240

cccuucaccu gcaaggccuu cguguucgac aaggccagaa agcagugccu gugguucccc      300

uucaacagca ugagcagcgg cgugaagaag gaguucggcc acgaguucga ccuguacgag      360

aacaaggacu acaucagaaa cugcaucauc ggcaagggca gaagcuacaa gggcaccgug      420

agcaucacca agagcggcau caagugccag cccuggagca gcaugauccc ccacgagcac      480

agcuuccugc ccagcagcua cagaggcaag gaccugcagg agaacuacug cagaaacccc      540

agaggcgagg agggcggccc cuggugcuuc accagcaacc ccgaggugag auacgaggug      600

ugcgacaucc cccagugcag cgagguggag ugcaugaccu gcaacggcga gagcuacaga      660

ggccugaugg accacaccga gagcggcaag aucugccaga gaugggacca ccagaccccc      720

cacagacaca aguuccugcc cgagagauac cccgacaagg gcuucgacga caacuacugc      780

agaaaccccg acggccagcc cagacccugg ugcuacaccc uggaccccca caccagaugg      840

gaguacugcg ccaucaagac cugcgccgac aacaccauga acgacaccga cgugccccug      900

gagaccaccg agugcaucca gggccagggc gagggcuaca gaggcaccgu gaacaccauc      960

uggaacggca uccccugcca gagaugggac agccaguacc cccacgagca cgacaugacc     1020

cccgagaacu ucaagugcaa ggaccugaga gagaacuacu gcagaaaccc cgacggcagc     1080

gagagccccu ggugcuucac caccgacccc aacaucagag ugggcuacug cagccagauc     1140

cccaacugcg acaugagcca cggccaggac ugcuacagag gcaacggcaa gaacuacaug     1200

ggcaaccuga gccagaccag aagcggccug accugcagca ugugggacaa gaacauggag     1260

gaccugcaca gacacaucuu cugggagccc gacgccagca agcugaacga gaacuacugc     1320

agaaaccccg acgacgacgc ccacggcccc uggugcuaca ccggcaaccc ccugaucccc     1380

ugggacuacu gccccaucag cagaugcgag ggcgacacca cccccaccau cgugaaccug     1440

gaccaccccg ugaucagcug cgccaagacc aagcagcuga gaguggugaa cggcaucccc     1500

accagaacca acaucggcug gauggugagc cugagauaca gaaacaagca caucugcggc     1560

ggcagccuga ucaaggagag cugggugcug accgccagac agugcuuccc cagcagagac     1620

cugaaggacu acgaggccug gcugggcauc cacgacgugc acggcagagg cgacgagaag     1680

ugcaagcagg ugcugaacgu gagccagcug guguacggcc ccgagggcag cgaccuggug     1740

cugaugaagc uggccagacc cgccgugcug gacgacuucg ugagcaccau cgaccugccc     1800

aacuacggcu gcaccauccc cgagaagacc agcugcagcg uguacggcug gggcuacacc     1860

ggccugauca acuacgacgg ccugcugaga guggcccacc uguacaucau gggcaacgag     1920

aagugcagcc agcaccacag aggcaaggug acccugaacg agagcgagau cugcgccggc     1980

gccgagaaga ucggcagcgg ccccugcgag ggcgacuacg gcggcccccu ggugugcgag     2040

cagcacaaga ugagaauggu gcugggcgug aucgugcccg gcagaggcug cgccaucccc     2100

aacagacccg gcaucuucgu gagaguggcc uacuacgcca aguggaucca caagaucauc     2160

cugaccuaca aggugcccca gagcuga                                         2187


<210>  551
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  551
auggccaagg ccgccgccau cggcaucgac cugggcacca ccuacagcug cgugggcgug       60

uuccagcacg gcaaggugga gaucaucgcc aacgaccagg gcaacagaac cacccccagc      120

uacguggccu ucaccgacac cgagagacug aucggcgacg ccgccaagaa ccagguggcc      180

cugaaccccc agaacaccgu guucgacgcc aagagacuga ucggcagaaa guucggcgac      240

cccguggugc agagcgacau gaagcacugg cccuuccagg ugaucaacga cggcgacaag      300

cccaaggugc aggugagcua caagggcgag accaaggccu ucuaccccga ggagaucagc      360

agcauggugc ugaccaagau gaaggagauc gccgaggccu accugggcua ccccgugacc      420

aacgccguga ucaccgugcc cgccuacuuc aacgacagcc agagacaggc caccaaggac      480

gccggcguga ucgccggccu gaacgugcug agaaucauca acgagcccac cgccgccgcc      540

aucgccuacg gccuggacag aaccggcaag ggcgagagaa acgugcugau cuucgaccug      600

ggcggcggca ccuucgacgu gagcauccug accaucgacg acggcaucuu cgaggugaag      660

gccaccgccg gcgacaccca ccugggcggc gaggacuucg acaacagacu ggugaaccac      720

uucguggagg aguucaagag aaagcacaag aaggacauca gccagaacaa gagagccgug      780

agaagacuga gaaccgccug cgagagagcc aagagaaccc ugagcagcag cacccaggcc      840

agccuggaga ucgacagccu guucgagggc aucgacuucu acaccagcau caccagagcc      900

agauucgagg agcugugcag cgaccuguuc agaagcaccc uggagcccgu ggagaaggcc      960

cugagagacg ccaagcugga caaggcccag auccacgacc uggugcuggu gggcggcagc     1020

accagaaucc ccaaggugca gaagcugcug caggacuucu ucaacggcag agaccugaac     1080

aagagcauca accccgacga ggccguggcc uacggcgccg ccgugcaggc cgccauccug     1140

augggcgaca agagcgagaa cgugcaggac cugcugcugc uggacguggc cccccugagc     1200

cugggccugg agaccgccgg cggcgugaug accgcccuga ucaagagaaa cagcaccauc     1260

cccaccaagc agacccagau cuucaccacc uacagcgaca accagcccgg cgugcugauc     1320

cagguguacg agggcgagag agccaugacc aaggacaaca accugcuggg cagauucgag     1380

cugagcggca ucccccccgc ccccagaggc gugccccaga ucgaggugac cuucgacauc     1440

gacgccaacg gcauccugaa cgugaccgcc accgacaaga gcaccggcaa ggccaacaag     1500

aucaccauca ccaacgacaa gggcagacug agcaaggagg agaucgagag aauggugcag     1560

gaggccgaga aguacaaggc cgaggacgag gugcagagag agagagugag cgccaagaac     1620

gcccuggaga gcuacgccuu caacaugaag agcgccgugg aggacgaggg ccugaagggc     1680

aagaucagcg aggccgacaa gaagaaggug cuggacaagu gccaggaggu gaucagcugg     1740

cuggacgcca acacccuggc cgagaaggac gaguucgagc acaagagaaa ggagcuggag     1800

caggugugca accccaucau cagcggccug uaccagggcg ccggcggccc cggccccggc     1860

ggcuucggcg cccagggccc caagggcggc agcggcagcg gccccaccau cgaggaggug     1920

gacuga                                                                1926


<210>  552
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  552
auggccaagg ccgccgccau cggcaucgac cugggcacca ccuacagcug cgugggcgug       60

uuccagcacg gcaaggugga gaucaucgcc aacgaccagg gcaacagaac cacccccagc      120

uacguggccu ucaccgacac cgagagacug aucggcgacg ccgccaagaa ccagguggcc      180

cugaaccccc agaacaccgu guucgacgcc aagagacuga ucggcagaaa guucggcgac      240

cccguggugc agagcgacau gaagcacugg cccuuccagg ugaucaacga cggcgacaag      300

cccaaggugc aggugagcua caagggcgag accaaggccu ucuaccccga ggagaucagc      360

agcauggugc ugaccaagau gaaggagauc gccgaggccu accugggcua ccccgugacc      420

aacgccguga ucaccgugcc cgccuacuuc aacgacagcc agagacaggc caccaaggac      480

gccggcguga ucgccggccu gaacgugcug agaaucauca acgagcccac cgccgccgcc      540

aucgccuacg gccuggacag aaccggcaag ggcgagagaa acgugcugau cuucgaccug      600

ggcggcggca ccuucgacgu gagcauccug accaucgacg acggcaucuu cgaggugaag      660

gccaccgccg gcgacaccca ccugggcggc gaggacuucg acaacagacu ggugaaccac      720

uucguggagg aguucaagag aaagcacaag aaggacauca gccagaacaa gagagccgug      780

agaagacuga gaaccgccug cgagagagcc aagagaaccc ugagcagcag cacccaggcc      840

agccuggaga ucgacagccu guucgagggc aucgacuucu acaccagcau caccagagcc      900

agauucgagg agcugugcag cgaccuguuc agaagcaccc uggagcccgu ggagaaggcc      960

cugagagacg ccaagcugga caaggcccag auccacgacc uggugcuggu gggcggcagc     1020

accagaaucc ccaaggugca gaagcugcug caggacuucu ucaacggcag agaccugaac     1080

aagagcauca accccgacga ggccguggcc uacggcgccg ccgugcaggc cgccauccug     1140

augggcgaca agagcgagaa cgugcaggac cugcugcugc uggacguggc cccccugagc     1200

cugggccugg agaccgccgg cggcgugaug accgcccuga ucaagagaaa cagcaccauc     1260

cccaccaagc agacccagau cuucaccacc uacagcgaca accagcccgg cgugcugauc     1320

cagguguacg agggcgagag agccaugacc aaggacaaca accugcuggg cagauucgag     1380

cugagcggca ucccccccgc ccccagaggc gugccccaga ucgaggugac cuucgacauc     1440

gacgccaacg gcauccugaa cgugaccgcc accgacaaga gcaccggcaa ggccaacaag     1500

aucaccauca ccaacgacaa gggcagacug agcaaggagg agaucgagag aauggugcag     1560

gaggccgaga aguacaaggc cgaggacgag gugcagagag agagagugag cgccaagaac     1620

gcccuggaga gcuacgccuu caacaugaag agcgccgugg aggacgaggg ccugaagggc     1680

aagaucagcg aggccgacaa gaagaaggug cuggacaagu gccaggaggu gaucagcugg     1740

cuggacgcca acacccuggc cgagaaggac gaguucgagc acaagagaaa ggagcuggag     1800

caggugugca accccaucau cagcggccug uaccagggcg ccggcggccc cggccccggc     1860

ggcuucggcg cccagggccc caagggcggc agcggcagcg gccccaccau cgaggaggug     1920

gacuga                                                                1926


<210>  553
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  553
auggccaccg ccaagggcau cgccaucggc aucgaccugg gcaccaccua cagcugcgug       60

ggcguguucc agcacggcaa gguggagauc aucgccaacg accagggcaa cagaaccacc      120

cccagcuacg uggccuucac cgacaccgag agacugaucg gcgacgccgc caagaaccag      180

guggccauga acccccagaa caccguguuc gacgccaaga gacugaucgg cagaaaguuc      240

aacgaccccg uggugcaggc cgacaugaag cuguggcccu uccaggugau caacgagggc      300

ggcaagccca aggugcuggu gagcuacaag ggcgagaaca aggccuucua ccccgaggag      360

aucagcagca uggugcugac caagcugaag gagaccgccg aggccuuccu gggccacccc      420

gugaccaacg ccgugaucac cgugcccgcc uacuucaacg acagccagag acaggccacc      480

aaggacgccg gcgugaucgc cggccugaac gugcugagaa ucaucaacga gcccaccgcc      540

gccgccaucg ccuacggccu ggacaagggc ggccagggcg agagacacgu gcugaucuuc      600

gaccugggcg gcggcaccuu cgacgugagc auccugacca ucgacgacgg caucuucgag      660

gugaaggcca ccgccggcga cacccaccug ggcggcgagg acuucgacaa cagacuggug      720

agccacuucg uggaggaguu caagagaaag cacaagaagg acaucagcca gaacaagaga      780

gccgugagaa gacugagaac cgccugcgag agagccaaga gaacccugag cagcagcacc      840

caggccaacc uggagaucga cagccuguac gagggcaucg acuucuacac cagcaucacc      900

agagccagau ucgaggagcu gugcgccgac cuguucagag gcacccugga gcccguggag      960

aaggcccuga gagacgccaa gauggacaag gccaagaucc acgacaucgu gcuggugggc     1020

ggcagcacca gaauccccaa ggugcagaga cugcugcagg acuacuucaa cggcagagac     1080

cugaacaaga gcaucaaccc cgacgaggcc guggccuacg gcgccgccgu gcaggccgcc     1140

auccugaugg gcgacaagag cgagaaggug caggaccugc ugcugcugga cguggccccc     1200

cugagccugg gccuggagac cgccggcggc gugaugaccg cccugaucaa gagaaacagc     1260

accaucccca ccaagcagac ccagaucuuc accaccuaca gcgacaacca gcccggcgug     1320

cugauccagg uguacgaggg cgagagagcc augaccaagg acaacaaccu gcugggcaga     1380

uucgaccuga ccggcauccc ccccgccccc agaggcgugc cccagaucga ggugaccuuc     1440

gacaucgacg ccaacggcau ccugaacgug accgccaccg acaagagcac cggcaaggug     1500

aacaagauca ccaucaccaa cgacaagggc agacugagca aggaggagau cgagagaaug     1560

gugcuggacg ccgagaagua caaggccgag gacgaggugc agagagagaa gaucgccgcc     1620

aagaacgccc uggagagcua cgccuucaac augaagagcg uggugagcga cgagggccug     1680

aagggcaaga ucagcgagag cgacaagaac aagauccugg acaagugcaa cgagcugcug     1740

agcuggcugg aggugaacca gcuggccgag aaggacgagu ucgaccacaa gagaaaggag     1800

cuggagcaga ugugcaaccc caucaucacc aagcuguacc agggcggcug caccggcccc     1860

gccugcggca ccggcuacgu gcccggcaga cccgccaccg gccccaccau cgaggaggug     1920

gacuga                                                                1926


<210>  554
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  554
augagcgcca gaggccccgc caucggcauc gaccugggca ccaccuacag cugcgugggc       60

guguuccagc acggcaaggu ggagaucauc gccaacgacc agggcaacag aaccaccccc      120

agcuacgugg ccuucaccga caccgagaga cugaucggcg acgccgccaa gaaccaggug      180

gccaugaacc ccaccaacac caucuucgac gccaagagac ugaucggcag aaaguucgag      240

gacgccaccg ugcagagcga caugaagcac uggcccuuca gaguggugag cgagggcggc      300

aagcccaagg ugcaggugga guacaagggc gagaccaaga ccuucuuccc cgaggagauc      360

agcagcaugg ugcugaccaa gaugaaggag aucgccgagg ccuaccuggg cggcaaggug      420

cacagcgccg ugaucaccgu gcccgccuac uucaacgaca gccagagaca ggccaccaag      480

gacgccggca ccaucaccgg ccugaacgug cugagaauca ucaacgagcc caccgccgcc      540

gccaucgccu acggccugga caagaagggc ugcgccggcg gcgagaagaa cgugcugauc      600

uucgaccugg gcggcggcac cuucgacgug agcauccuga ccaucgagga cggcaucuuc      660

gaggugaaga gcaccgccgg cgacacccac cugggcggcg aggacuucga caacagaaug      720

gugagccacc uggccgagga guucaagaga aagcacaaga aggacaucgg ccccaacaag      780

agagccguga gaagacugag aaccgccugc gagagagcca agagaacccu gagcagcagc      840

acccaggcca gcaucgagau cgacagccug uacgagggcg uggacuucua caccagcauc      900

accagagcca gauucgagga gcugaacgcc gaccuguuca gaggcacccu ggagcccgug      960

gagaaggccc ugagagacgc caagcuggac aagggccaga uccaggagau cgugcuggug     1020

ggcggcagca ccagaauccc caagauccag aagcugcugc aggacuucuu caacggcaag     1080

gagcugaaca agagcaucaa ccccgacgag gccguggccu acggcgccgc cgugcaggcc     1140

gccauccuga ucggcgacaa gagcgagaac gugcaggacc ugcugcugcu ggacgugacc     1200

ccccugagcc ugggcaucga gaccgccggc ggcgugauga ccccccugau caagagaaac     1260

accaccaucc ccaccaagca gacccagacc uucaccaccu acagcgacaa ccagagcagc     1320

gugcuggugc agguguacga gggcgagaga gccaugacca aggacaacaa ccugcugggc     1380

aaguucgacc ugaccggcau cccccccgcc cccagaggcg ugccccagau cgaggugacc     1440

uucgacaucg acgccaacgg cauccugaac gugaccgccg ccgacaagag caccggcaag     1500

gagaacaaga ucaccaucac caacgacaag ggcagacuga gcaaggacga caucgacaga     1560

auggugcagg aggccgagag auacaagagc gaggacgagg ccaacagaga cagaguggcc     1620

gccaagaacg cccuggagag cuacaccuac aacaucaagc agaccgugga ggacgagaag     1680

cugagaggca agaucagcga gcaggacaag aacaagaucc uggacaagug ccaggaggug     1740

aucaacuggc uggacagaaa ccagauggcc gagaaggacg aguacgagca caagcagaag     1800

gagcuggaga gagugugcaa ccccaucauc agcaagcugu accagggcgg ccccggcggc     1860

ggcagcggcg gcggcggcag cggcgccagc ggcggcccca ccaucgagga gguggacuga     1920


<210>  555
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  555
augagcgugg ugggcaucga ccugggcuuc cagagcugcu acguggccgu ggccagagcc       60

ggcggcaucg agaccaucgc caacgaguac agcgacagau gcacccccgc cugcaucagc      120

uucggcccca agaacagaag caucggcgcc gccgccaaga gccaggugau cagcaacgcc      180

aagaacaccg ugcagggcuu caagagauuc cacggcagag ccuucagcga ccccuucgug      240

gaggccgaga agagcaaccu ggccuacgac aucgugcagc ugcccaccgg ccugaccggc      300

aucaagguga ccuacaugga ggaggagaga aacuucacca ccgagcaggu gaccgccaug      360

cugcugagca agcugaagga gaccgccgag agcgugcuga agaagcccgu gguggacugc      420

guggugagcg ugcccugcuu cuacaccgac gccgagagaa gaagcgugau ggacgccacc      480

cagaucgccg gccugaacug ccugagacug augaacgaga ccaccgccgu ggcccuggcc      540

uacggcaucu acaagcagga ccugcccgcc cuggaggaga agcccagaaa cgugguguuc      600

guggacaugg gccacagcgc cuaccaggug agcgugugcg ccuucaacag aggcaagcug      660

aaggugcugg ccaccgccuu cgacaccacc cugggcggca gaaaguucga cgaggugcug      720

gugaaccacu ucugcgagga guucggcaag aaguacaagc uggacaucaa gagcaagauc      780

agagcccugc ugagacugag ccaggagugc gagaagcuga agaagcugau gagcgccaac      840

gccagcgacc ugccccugag caucgagugc uucaugaacg acguggacgu gagcggcacc      900

augaacagag gcaaguuccu ggagaugugc aacgaccugc uggccagagu ggagcccccc      960

cugagaagcg ugcuggagca gaccaagcug aagaaggagg acaucuacgc cguggagauc     1020

gugggcggcg ccaccagaau ccccgccgug aaggagaaga ucagcaaguu cuucggcaag     1080

gagcugagca ccacccugaa cgccgacgag gccgugacca gaggcugcgc ccugcagugc     1140

gccauccuga gccccgccuu caaggugaga gaguucagca ucaccgacgu ggugcccuac     1200

cccaucagcc ugagauggaa cagccccgcc gaggagggca gcagcgacug cgagguguuc     1260

agcaagaacc acgccgcccc cuucagcaag gugcugaccu ucuacagaaa ggagcccuuc     1320

acccuggagg ccuacuacag cagcccccag gaccugcccu accccgaccc cgccaucgcc     1380

caguucagcg ugcagaaggu gaccccccag agcgacggca gcagcagcaa ggugaaggug     1440

aaggugagag ugaacgugca cggcaucuuc agcgugagca gcgccagccu gguggaggug     1500

cacaagagcg aggagaacga ggagcccaug gagaccgacc agaacgccaa ggaggaggag     1560

aagaugcagg uggaccagga ggagccccac guggaggagc agcagcagca gacccccgcc     1620

gagaacaagg ccgagagcga ggagauggag accagccagg ccggcagcaa ggacaagaag     1680

auggaccagc ccccccaggc caagaaggcc aaggugaaga ccagcaccgu ggaccugccc     1740

aucgagaacc agcugcugug gcagaucgac agagagaugc ugaaccugua caucgagaac     1800

gagggcaaga ugaucaugca ggacaagcug gagaaggaga gaaacgacgc caagaacgcc     1860

guggaggagu acguguacga gaugagagac aagcugagcg gcgaguacga gaaguucgug     1920

agcgaggacg acagaaacag cuucacccug aagcuggagg acaccgagaa cuggcuguac     1980

gaggacggcg aggaccagcc caagcaggug uacguggaca agcuggccga gcugaagaac     2040

cugggccagc ccaucaagau cagauuccag gagagcgagg agagacccaa gcuguucgag     2100

gagcugggca agcagaucca gcaguacaug aagaucauca gcagcuucaa gaacaaggag     2160

gaccaguacg accaccugga cgccgccgac augaccaagg uggagaagag caccaacgag     2220

gccauggagu ggaugaacaa caagcugaac cugcagaaca agcagagccu gaccauggac     2280

cccgugguga agagcaagga gaucgaggcc aagaucaagg agcugaccag caccugcagc     2340

cccaucauca gcaagcccaa gcccaaggug gagcccccca aggaggagca gaagaacgcc     2400

gagcagaacg gccccgugga cggccagggc gacaaccccg gcccccaggc cgccgagcag     2460

ggcaccgaca ccgccgugcc cagcgacagc gacaagaagc ugcccgagau ggacaucgac     2520

uga                                                                   2523


<210>  556
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  556
augagcgugg ugggcaucga ccugggcuuc cugaacugcu acaucgccgu ggccagaagc       60

ggcggcaucg agaccaucgc caacgaguac agcgacagau gcacccccgc cugcaucagc      120

cugggcagca gaaccagagc caucggcaac gccgccaaga gccagaucgu gaccaacgug      180

agaaacacca uccacggcuu caagaagcug cacggcagaa gcuucgacga ccccaucgug      240

cagaccgaga gaaucagacu gcccuacgag cugcagaaga ugcccaacgg cagcgccggc      300

gugaagguga gauaccugga ggaggagaga cccuucgcca ucgagcaggu gaccggcaug      360

cugcuggcca agcugaagga gaccagcgag aacgcccuga agaagcccgu ggccgacugc      420

gugaucagca uccccagcuu cuucaccgac gccgagagaa gaagcgugau ggccgccgcc      480

cagguggccg gccugaacug ccugagacug augaacgaga ccaccgccgu ggcccuggcc      540

uacggcaucu acaagcagga ccugcccccc cuggacgaga agcccagaaa cgugguguuc      600

aucgacaugg gccacagcgc cuaccaggug cuggugugcg ccuucaacaa gggcaagcug      660

aaggugcugg ccaccaccuu cgaccccuac cugggcggca gaaacuucga cgaggcccug      720

guggacuacu ucugcgacga guucaagacc aaguacaaga ucaacgugaa ggagaacagc      780

agagcccugc ugagacugua ccaggagugc gagaagcuga agaagcugau gagcgccaac      840

gccagcgacc ugccccugaa caucgagugc uucaugaacg accuggacgu gagcagcaag      900

augaacagag cccaguucga gcagcugugc gccagccugc uggccagagu ggagcccccc      960

cugaaggccg ugauggagca ggccaaccug cagagagagg acaucagcag caucgagauc     1020

gugggcggcg ccaccagaau ccccgccgug aaggagcaga ucaccaaguu cuuccugaag     1080

gacaucagca ccacccugaa cgccgacgag gccguggcca gaggcugcgc ccugcagugc     1140

gccauccuga gccccgccuu caaggugaga gaguucagca ucaccgaccu ggugcccuac     1200

agcaucaccc ugagauggaa gaccagcuuc gaggacggca gcggcgagug cgagguguuc     1260

ugcaagaacc accccgcccc cuucagcaag gugaucaccu uccacaagaa ggagcccuuc     1320

gagcuggagg ccuucuacac caaccugcac gaggugcccu accccgacgc cagaaucggc     1380

agcuucacca uccagaacgu guucccccag agcgacggcg acagcagcaa ggugaaggug     1440

aaggugagag ugaacaucca cggcaucuuc agcguggcca gcgccagcgu gaucgagaag     1500

cagaaccugg agggcgacca cagcgacgcc cccauggaga ccgagaccag cuucaagaac     1560

gagaacaagg acaacaugga caagaugcag guggaccagg aggagggcca ccagaagugc     1620

cacgccgagc acacccccga ggaggagauc gaccacaccg gcgccaagac caagagcgcc     1680

gugagcgaca agcaggacag acugaaccag acccugaaga agggcaaggu gaagagcauc     1740

gaccugccca uccagagcag ccugugcaga cagcugggcc aggaccugcu gaacagcuac     1800

aucgagaacg agggcaagau gaucaugcag gacaagcugg agaaggagag aaacgacgcc     1860

aagaacgccg uggaggagua cguguacgac uucagagaca gacugggcac cguguacgag     1920

aaguucauca cccccgagga ccugagcaag cugagcgccg ugcuggagga caccgagaac     1980

uggcuguacg aggacggcga ggaccagccc aagcaggugu acguggacaa gcugcaggag     2040

cugaagaagu acggccagcc cauccagaug aaguacaugg agcacgagga gagacccaag     2100

gcccugaacg accugggcaa gaagauccag cuggugauga aggugaucga ggccuacaga     2160

aacaaggacg agagauacga ccaccuggac cccaccgaga uggagaaggu ggagaagugc     2220

aucagcgacg ccaugagcug gcugaacagc aagaugaacg cccagaacaa gcugagccug     2280

acccaggacc ccguggugaa ggugagcgag aucguggcca agagcaagga gcuggacaac     2340

uucugcaacc ccaucaucua caagcccaag cccaaggccg aggugcccga ggacaagccc     2400

aaggccaaca gcgagcacaa cggccccaug gacggccaga gcggcaccga gaccaagagc     2460

gacagcacca aggacagcag ccagcacacc aagagcagcg gcgagaugga gguggacuga     2520


<210>  557
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  557
augaagcuga gccugguggc cgccaugcug cugcugcuga gcgccgccag agccgaggag       60

gaggacaaga aggaggacgu gggcaccgug gugggcaucg accugggcac caccuacagc      120

ugcgugggcg uguucaagaa cggcagagug gagaucaucg ccaacgacca gggcaacaga      180

aucaccccca gcuacguggc cuucaccccc gagggcgaga gacugaucgg cgacgccgcc      240

aagaaccagc ugaccagcaa ccccgagaac accguguucg acgccaagag acugaucggc      300

agaaccugga acgaccccag cgugcagcag gacaucaagu uccugcccuu caagguggug      360

gagaagaaga ccaagcccua cauccaggug gacaucggcg gcggccagac caagaccuuc      420

gcccccgagg agaucagcgc cauggugcug accaagauga aggagaccgc cgaggccuac      480

cugggcaaga aggugaccca cgccguggug accgugcccg ccuacuucaa cgacgcccag      540

agacaggcca ccaaggacgc cggcaccauc gccggccuga acgugaugag aaucaucaac      600

gagcccaccg ccgccgccau cgccuacggc cuggacaaga gagagggcga gaagaacauc      660

cugguguucg accugggcgg cggcaccuuc gacgugagcc ugcugaccau cgacaacggc      720

guguucgagg ugguggccac caacggcgac acccaccugg gcggcgagga cuucgaccag      780

agagugaugg agcacuucau caagcuguac aagaagaaga ccggcaagga cgugagaaag      840

gacaacagag ccgugcagaa gcugagaaga gagguggaga aggccaagag agcccugagc      900

agccagcacc aggccagaau cgagaucgag agcuucuacg agggcgagga cuucagcgag      960

acccugacca gagccaaguu cgaggagcug aacauggacc uguucagaag caccaugaag     1020

cccgugcaga aggugcugga ggacagcgac cugaagaaga gcgacaucga cgagaucgug     1080

cuggugggcg gcagcaccag aauccccaag auccagcagc uggugaagga guucuucaac     1140

ggcaaggagc ccagcagagg caucaacccc gacgaggccg uggccuacgg cgccgccgug     1200

caggccggcg ugcugagcgg cgaccaggac accggcgacc uggugcugcu ggacgugugc     1260

ccccugaccc ugggcaucga gaccgugggc ggcgugauga ccaagcugau ccccagaaac     1320

accguggugc ccaccaagaa gagccagauc uucagcaccg ccagcgacaa ccagcccacc     1380

gugaccauca agguguacga gggcgagaga ccccugacca aggacaacca ccugcugggc     1440

accuucgacc ugaccggcau cccccccgcc cccagaggcg ugccccagau cgaggugacc     1500

uucgagaucg acgugaacgg cauccugaga gugaccgccg aggacaaggg caccggcaac     1560

aagaacaaga ucaccaucac caacgaccag aacagacuga cccccgagga gaucgagaga     1620

auggugaacg acgccgagaa guucgccgag gaggacaaga agcugaagga gagaaucgac     1680

accagaaacg agcuggagag cuacgccuac agccugaaga accagaucgg cgacaaggag     1740

aagcugggcg gcaagcugag cagcgaggac aaggagacca uggagaaggc cguggaggag     1800

aagaucgagu ggcuggagag ccaccaggac gccgacaucg aggacuucaa ggccaagaag     1860

aaggagcugg aggagaucgu gcagcccauc aucagcaagc uguacggcag cgccggcccc     1920

ccccccaccg gcgaggagga caccgccgag aaggacgagc uguga                     1965


<210>  558
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  558
augcaggccc ccagagagcu ggccgugggc aucgaccugg gcaccaccua cagcugcgug       60

ggcguguucc agcagggcag aguggagauc cuggccaacg accagggcaa cagaaccacc      120

cccagcuacg uggccuucac cgacaccgag agacuggugg gcgacgccgc caagagccag      180

gccgcccuga acccccacaa caccguguuc gacgccaaga gacugaucgg cagaaaguuc      240

gccgacacca ccgugcagag cgacaugaag cacuggcccu ucagaguggu gagcgagggc      300

ggcaagccca aggugagagu gugcuacaga ggcgaggaca agaccuucua ccccgaggag      360

aucagcagca uggugcugag caagaugaag gagaccgccg aggccuaccu gggccagccc      420

gugaagcacg ccgugaucac cgugcccgcc uacuucaacg acagccagag acaggccacc      480

aaggacgccg gcgccaucgc cggccugaac gugcugagaa ucaucaacga gcccaccgcc      540

gccgccaucg ccuacggccu ggacagaaga ggcgccggcg agagaaacgu gcugaucuuc      600

gaccugggcg gcggcaccuu cgacgugagc gugcugagca ucgacgccgg cguguucgag      660

gugaaggcca ccgccggcga cacccaccug ggcggcgagg acuucgacaa cagacuggug      720

aaccacuuca uggaggaguu cagaagaaag cacggcaagg accugagcgg caacaagaga      780

gcccugagaa gacugagaac cgccugcgag agagccaaga gaacccugag cagcagcacc      840

caggccaccc uggagaucga cagccuguuc gagggcgugg acuucuacac cagcaucacc      900

agagccagau ucgaggagcu gugcagcgac cuguucagaa gcacccugga gcccguggag      960

aaggcccuga gagacgccaa gcuggacaag gcccagaucc acgacguggu gcuggugggc     1020

ggcagcacca gaauccccaa ggugcagaag cugcugcagg acuucuucaa cggcaaggag     1080

cugaacaaga gcaucaaccc cgacgaggcc guggccuacg gcgccgccgu gcaggccgcc     1140

gugcugaugg gcgacaagug cgagaaggug caggaccugc ugcugcugga cguggccccc     1200

cugagccugg gccuggagac cgccggcggc gugaugacca cccugaucca gagaaacgcc     1260

accaucccca ccaagcagac ccagaccuuc accaccuaca gcgacaacca gcccggcgug     1320

uucauccagg uguacgaggg cgagagagcc augaccaagg acaacaaccu gcugggcaga     1380

uucgagcuga gcggcauccc ccccgccccc agaggcgugc cccagaucga ggugaccuuc     1440

gacaucgacg ccaacggcau ccugagcgug accgccaccg acagaagcac cggcaaggcc     1500

aacaagauca ccaucaccaa cgacaagggc agacugagca aggaggaggu ggagagaaug     1560

gugcacgagg ccgagcagua caaggccgag gacgaggccc agagagacag aguggccgcc     1620

aagaacagcc uggaggccca cguguuccac gugaagggca gccugcagga ggagagccug     1680

agagacaaga uccccgagga ggacagaaga aagaugcagg acaagugcag agaggugcug     1740

gccuggcugg agcacaacca gcuggccgag aaggaggagu acgagcacca gaagagagag     1800

cuggagcaga ucugcagacc caucuucagc agacuguacg gcggccccgg cgugcccggc     1860

ggcagcagcu gcggcaccca ggccagacag ggcgacccca gcaccggccc caucaucgag     1920

gagguggacu ga                                                         1932


<210>  559
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__P48741__HsHSPA7

<400>  559
augcaggccc ccagagagcu ggccgugggc aucgaccugg gcaccaccua cagcugcgug       60

ggcguguucc agcagggcag aguggagauc cuggccaacg accagggcaa cagaaccacc      120

cccagcuacg uggccuucac cgacaccgag agacuggugg gcgacgccgc caagagccag      180

gccgcccuga acccccacaa caccguguuc gacgccaaga gacugaucgg cagaaaguuc      240

gccgacacca ccgugcagag cgacaugaag cacuggcccu uccagguggu gagcgagggc      300

ggcaagccca aggugagagu gugcuacaga ggcgaggaca agaccuucua ccccgaggag      360

aucagcagca uggugcugag caagaugaag gagaccgccg aggccuaccu gggccagccc      420

gugaagcacg ccgugaucac cgugcccacc uacuucagca acagccagag acaggccacc      480

aaggacgccg gcgccaucgc cggccugaag gugcugccca ucaucaacga ggccaccgcc      540

gccgccaucg ccuacggccu ggacagaaga ggcgccggca agagaaacgu gcugaucuuc      600

gaccugggcg gcggcaccuu cgacgugagc gugcugagca ucgacgccgg cguguucgag      660

gugaaggcca ccgccggcga cacccaccug ggcggcgagg acuucgacaa cagacuggug      720

aaccacuuca uggaggaguu cagaagaaag cacggcaagg accugagcgg caacaagaga      780

gcccugagaa gacugagaac cgccugcgag agagccaaga gaacccccag cagcagcacc      840

caggccaccc uggagaucga cagccuguuc gagggcgugg acuucuacaa gagcaucacc      900

agagccagau ucgaggagcu gugcagcgac cuguucagaa gcacccugga gcccguggag      960

aaggcccuga gagacgccaa gcuggacaag gcccagaucc acgacuucgu gcugggcggc     1020

ggccugcaca gccaccccca gggcgccgag guggccgccg gccugcugca gagacagggc     1080

gccgagcagg agcaccagcc cuga                                            1104


<210>  560
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  560
augagcaagg gccccgccgu gggcaucgac cugggcacca ccuacagcug cgugggcgug       60

uuccagcacg gcaaggugga gaucaucgcc aacgaccagg gcaacagaac cacccccagc      120

uacguggccu ucaccgacac cgagagacug aucggcgacg ccgccaagaa ccagguggcc      180

augaacccca ccaacaccgu guucgacgcc aagagacuga ucggcagaag auucgacgac      240

gccguggugc agagcgacau gaagcacugg cccuucaugg uggugaacga cgccggcaga      300

cccaaggugc agguggagua caagggcgag accaagagcu ucuaccccga ggaggugagc      360

agcauggugc ugaccaagau gaaggagauc gccgaggccu accugggcaa gaccgugacc      420

aacgccgugg ugaccgugcc cgccuacuuc aacgacagcc agagacaggc caccaaggac      480

gccggcacca ucgccggccu gaacgugcug agaaucauca acgagcccac cgccgccgcc      540

aucgccuacg gccuggacaa gaaggugggc gccgagagaa acgugcugau cuucgaccug      600

ggcggcggca ccuucgacgu gagcauccug accaucgagg acggcaucuu cgaggugaag      660

agcaccgccg gcgacaccca ccugggcggc gaggacuucg acaacagaau ggugaaccac      720

uucaucgccg aguucaagag aaagcacaag aaggacauca gcgagaacaa gagagccgug      780

agaagacuga gaaccgccug cgagagagcc aagagaaccc ugagcagcag cacccaggcc      840

agcaucgaga ucgacagccu guacgagggc aucgacuucu acaccagcau caccagagcc      900

agauucgagg agcugaacgc cgaccuguuc agaggcaccc uggaccccgu ggagaaggcc      960

cugagagacg ccaagcugga caagagccag auccacgaca ucgugcuggu gggcggcagc     1020

accagaaucc ccaagaucca gaagcugcug caggacuucu ucaacggcaa ggagcugaac     1080

aagagcauca accccgacga ggccguggcc uacggcgccg ccgugcaggc cgccauccug     1140

agcggcgaca agagcgagaa cgugcaggac cugcugcugc uggacgugac cccccugagc     1200

cugggcaucg agaccgccgg cggcgugaug accgugcuga ucaagagaaa caccaccauc     1260

cccaccaagc agacccagac cuucaccacc uacagcgaca accagcccgg cgugcugauc     1320

cagguguacg agggcgagag agccaugacc aaggacaaca accugcuggg caaguucgag     1380

cugaccggca ucccccccgc ccccagaggc gugccccaga ucgaggugac cuucgacauc     1440

gacgccaacg gcauccugaa cgugagcgcc guggacaaga gcaccggcaa ggagaacaag     1500

aucaccauca ccaacgacaa gggcagacug agcaaggagg acaucgagag aauggugcag     1560

gaggccgaga aguacaaggc cgaggacgag aagcagagag acaaggugag cagcaagaac     1620

agccuggaga gcuacgccuu caacaugaag gccaccgugg aggacgagaa gcugcagggc     1680

aagaucaacg acgaggacaa gcagaagauc cuggacaagu gcaacgagau caucaacugg     1740

cuggacaaga accagaccgc cgagaaggag gaguucgagc accagcagaa ggagcuggag     1800

aaggugugca accccaucau caccaagcug uaccagagcg ccggcggcau gcccggcggc     1860

augcccggcg gcuuccccgg cggcggcgcc ccccccagcg gcggcgccag cagcggcccc     1920

accaucgagg agguggacug a                                               1941


<210>  561
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  561
augaucagcg ccagcagagc cgccgccgcc agacuggugg gcgccgccgc cagcagaggc       60

cccaccgccg ccagacacca ggacagcugg aacggccuga gccacgaggc cuucagacug      120

gugagcagaa gagacuacgc cagcgaggcc aucaagggcg ccgugguggg caucgaccug      180

ggcaccacca acagcugcgu ggccgugaug gagggcaagc aggccaaggu gcuggagaac      240

gccgagggcg ccagaaccac ccccagcgug guggccuuca ccgccgacgg cgagagacug      300

gugggcaugc ccgccaagag acaggccgug accaacccca acaacaccuu cuacgccacc      360

aagagacuga ucggcagaag auacgacgac cccgaggugc agaaggacau caagaacgug      420

cccuucaaga ucgugagagc cagcaacggc gacgccuggg uggaggccca cggcaagcug      480

uacagcccca gccagaucgg cgccuucgug cugaugaaga ugaaggagac cgccgagaac      540

uaccugggcc acaccgccaa gaacgccgug aucaccgugc ccgccuacuu caacgacagc      600

cagagacagg ccaccaagga cgccggccag aucagcggcc ugaacgugcu gagagugauc      660

aacgagccca ccgccgccgc ccuggccuac ggccuggaca agagcgagga caaggugauc      720

gccguguacg accugggcgg cggcaccuuc gacaucagca uccuggagau ccagaagggc      780

guguucgagg ugaagagcac caacggcgac accuuccugg gcggcgagga cuucgaccag      840

gcccugcuga gacacaucgu gaaggaguuc aagagagaga ccggcgugga ccugaccaag      900

gacaacaugg cccugcagag agugagagag gccgccgaga aggccaagug cgagcugagc      960

agcagcgugc agaccgacau caaccugccc uaccugacca uggacagcag cggccccaag     1020

caccugaaca ugaagcugac cagagcccag uucgagggca ucgugaccga ccugaucaga     1080

agaaccaucg cccccugcca gaaggccaug caggacgccg aggugagcaa gagcgacauc     1140

ggcgagguga uccugguggg cggcaugacc agaaugccca aggugcagca gaccgugcag     1200

gaccuguucg gcagagcccc cagcaaggcc gugaaccccg acgaggccgu ggccaucggc     1260

gccgccaucc agggcggcgu gcuggccggc gacgugaccg acgugcugcu gcuggacgug     1320

accccccuga gccugggcau cgagacccug ggcggcgugu ucaccaagcu gaucaacaga     1380

aacaccacca uccccaccaa gaagagccag guguucagca ccgccgccga cggccagacc     1440

cagguggaga ucaaggugug ccagggcgag agagagaugg ccggcgacaa caagcugcug     1500

ggccaguuca cccugaucgg cauccccccc gcccccagag gcgugcccca gaucgaggug     1560

accuucgaca ucgacgccaa cggcaucgug cacgugagcg ccaaggacaa gggcaccggc     1620

agagagcagc agaucgugau ccagagcagc ggcggccuga gcaaggacga caucgagaac     1680

auggugaaga acgccgagaa guacgccgag gaggacagaa gaaagaagga gagaguggag     1740

gccgugaaca uggccgaggg caucauccac gacaccgaga ccaagaugga ggaguucaag     1800

gaccagcugc ccgccgacga gugcaacaag cugaaggagg agaucagcaa gaugagagag     1860

cugcuggcca gaaaggacag cgagaccggc gagaacauca gacaggccgc cagcagccug     1920

cagcaggcca gccugaagcu guucgagaug gccuacaaga agauggccag cgagagagag     1980

ggcagcggca gcagcggcac cggcgagcag aaggaggacc agaaggagga gaagcaguga     2040


<210>  562
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  562
auggccgaca aggaggccgg cggcagcgac ggccccagag agaccgcccc caccagcgcc       60

uacagcagcc ccgccagaag ccugggcgac accggcauca ccccccugag ccccagccac      120

aucgugaacg acaccgacag caacgugagc gagcagcaga gcuuccuggu ggugguggcc      180

guggacuucg gcaccaccag cagcggcuac gccuacagcu ucaccaagga gcccgagugc      240

auccacguga ugagaagaug ggagggcggc gaccccggcg ugagcaacca gaagaccccc      300

accaccaucc ugcugacccc cgagagaaag uuccacagcu ucggcuacgc cgccagagac      360

uucuaccacg accuggaccc caacgaggcc aagcaguggc uguaccugga gaaguucaag      420

augaagcugc acaccaccgg cgaccugacc auggacaccg accugaccgc cgccaacggc      480

aagaagguga aggcccugga gaucuucgcc uacgcccugc aguacuucaa ggagcaggcc      540

cugaaggagc ugagcgacca ggccggcagc gaguucgaga acagcgacgu gagaugggug      600

aucaccgugc ccgccaucug gaagcagccc gccaagcagu ucaugagaca ggccgccuac      660

caggccggcc uggccagccc cgagaacagc gagcagcuga ucaucgcccu ggagcccgag      720

gccgccagca ucuacugcag aaagcugaga cugcaccaga ugaucgagcu gagcagcaag      780

gccgccguga acggcuacag cggcagcgac accgugggcg ccggcuucac ccaggccaag      840

gagcacauca gaagaaacag acagagcaga accuuccugg uggagaacgu gaucggcgag      900

aucuggagcg agcuggagga gggcgacaag uacguggugg uggacagcgg cggcggcacc      960

guggaccuga ccgugcacca gaucagacug cccgagggcc accugaagga gcuguacaag     1020

gccaccggcg gccccuacgg cagccugggc guggacuacg aguucgagaa gcugcuguac     1080

aagaucuucg gcgaggacuu caucgagcag uucaagauca agagacccgc cgccugggug     1140

gaccugauga ucgccuucga gagcagaaag agagccgccg cccccgacag aaccaacccc     1200

cugaacauca cccugcccuu cagcuucauc gacuacuaca agaaguucag aggccacagc     1260

guggagcacg cccugagaaa gagcaacgug gacuucguga aguggagcag ccagggcaug     1320

cugagaauga gccccgacgc caugaacgcc cuguucaagc ccaccaucga cagcaucauc     1380

gagcaccuga gagaccuguu ccagaagccc gaggugagca ccgugaaguu ccuguuccug     1440

gugggcggcu ucgccgaggc cccccugcug cagcaggccg ugcaggccgc cuucggcgac     1500

cagugcagaa ucaucauccc ccaggacgug ggccugacca uccugaaggg cgccgugcug     1560

uucggccugg accccgccgu gaucaaggug agaagaagcc cccugaccua cggcgugggc     1620

gugcugaaca gauacgugga gggcaagcac ccccccgaga agcugcuggu gaaggacggc     1680

accagauggu gcaccgacgu guucgacaag uucaucagcg ccgaccagag cguggcccug     1740

ggcgagcugg ugaagagaag cuacaccccc gccaagccca gccagcuggu gaucgugauc     1800

aacaucuaca gcagcgagca cgacaacgug agcuucauca ccgaccccgg cgugaagaag     1860

ugcggcaccc ugagacugga ccugaccggc accagcggca ccgccgugcc cgccagaaga     1920

gagauccaga cccugaugca guucggcgac accgagauca aggccaccgc caucgacauc     1980

gccaccagca agagcgugaa ggugggcauc gacuuccuga acuacuga                  2028


<210>  563
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  563
augcuggccg ugcccgagau gggccugcag ggccuguaca ucggcagcag ccccgagaga       60

agccccgugc ccagcccccc cggcagcccc agaacccagg agagcugcgg caucgccccc      120

cugaccccca gccagagccc caagcccgag gugagagccc cccagcaggc cagcuucagc      180

gugguggugg ccaucgacuu cggcaccacc agcagcggcu acgccuucag cuucgccagc      240

gaccccgagg ccauccacau gaugagaaag ugggagggcg gcgaccccgg cguggcccac      300

cagaagaccc ccaccugccu gcugcugacc cccgagggcg ccuuccacag cuucggcuac      360

accgccagag acuacuacca cgaccuggac cccgaggagg ccagagacug gcuguacuuc      420

gagaaguuca agaugaagau ccacagcgcc accgaccuga cccugaagac ccagcuggag      480

gccgugaacg gcaagaccau gcccgcccug gagguguucg cccacgcccu gagauucuuc      540

agagagcacg cccugcagga gcugagagag cagagcccca gccugcccga gaaggacacc      600

gugagauggg ugcugaccgu gcccgccauc uggaagcagc ccgccaagca guucaugaga      660

gaggccgccu accuggccgg ccuggugagc agagagaacg ccgagcagcu gcugaucgcc      720

cuggagcccg aggccgccag cguguacugc agaaagcuga gacugcacca gcugcuggac      780

cugagcggca gagcccccgg cggcggcaga cugggcgaga gaagaagcau cgacagcagc      840

uucagacagg ccagagagca gcugagaaga agcagacaca gcagaaccuu ccugguggag      900

agcggcgugg gcgagcugug ggccgagaug caggccggcg acagauacgu gguggccgac      960

ugcggcggcg gcaccgugga ccugaccgug caccagcugg agcagcccca cggcacccug     1020

aaggagcugu acaaggccag cggcggcccc uacggcgccg ugggcgugga ccuggccuuc     1080

gagcagcugc ugugcagaau cuucggcgag gacuucaucg ccaccuucaa gagacagaga     1140

cccgccgccu ggguggaccu gaccaucgcc uucgaggcca gaaagagaac cgccggcccc     1200

cacagagccg gcgcccugaa caucagccug cccuucagcu ucaucgacuu cuacagaaag     1260

cagagaggcc acaacgugga gaccgcccug agaagaagca gcgugaacuu cgugaagugg     1320

agcagccagg gcaugcugag aaugagcugc gaggccauga acgagcuguu ccagcccacc     1380

gugagcggca ucauccagca caucgaggcc cugcuggcca gacccgaggu gcagggcgug     1440

aagcugcugu uccugguggg cggcuucgcc gagagcgccg ugcugcagca cgccgugcag     1500

gccgcccugg gcgccagagg ccugagagug guggugcccc acgacguggg ccugaccauc     1560

cugaagggcg ccgugcuguu cggccaggcc cccggcgugg ugagagugag aagaagcccc     1620

cugaccuacg gcgugggcgu gcugaacaga uucgugcccg gcagacaccc ccccgagaag     1680

cugcugguga gagacggcag aagauggugc accgacgugu ucgagagauu cguggccgcc     1740

gagcagagcg uggcccuggg cgaggaggug agaagaagcu acugccccgc cagacccggc     1800

cagagaagag ugcugaucaa ccuguacugc ugcgccgccg aggacgccag auucaucacc     1860

gaccccggcg ugagaaagug cggcgcccug agccuggagc uggagcccgc cgacugcggc     1920

caggacaccg ccggcgcccc ccccggcaga agagagauca gagccgccau gcaguucggc     1980

gacaccgaga ucaaggugac cgccguggac gugagcacca acagaagcgu gagagccagc     2040

aucgacuucc ugagcaacug a                                               2061


<210>  564
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  564
auggccagag agaugaccau ccugggcagc gccgugcuga cccugcugcu ggccggcuac       60

cuggcccagc aguaccugcc ccugcccacc cccaagguga ucggcaucga ccugggcacc      120

accuacugca gcgugggcgu guucuucccc ggcaccggca aggugaaggu gauccccgac      180

gagaacggcc acaucagcau ccccagcaug gugagcuuca ccgacaacga cguguacgug      240

ggcuacgaga gcguggagcu ggccgacagc aacccccaga acaccaucua cgacgccaag      300

agauucaucg gcaagaucuu caccgccgag gagcuggagg ccgagaucgg cagauacccc      360

uucaaggugc ugaacaagaa cggcauggug gaguucagcg ugaccagcaa cgagaccauc      420

accgugagcc ccgaguacgu gggcagcaga cugcugcuga agcugaagga gauggccgag      480

gccuaccugg gcaugcccgu ggccaacgcc gugaucagcg ugcccgccga guucgaccug      540

aagcagagaa acagcaccau cgaggccgcc aaccuggccg gccugaagau ccugagagug      600

aucaacgagc ccaccgccgc cgccauggcc uacggccugc acaaggccga cguguuccac      660

gugcugguga ucgaccuggg cggcggcacc cuggacguga gccugcugaa caagcagggc      720

ggcauguucc ugaccagagc caugagcggc aacaacaagc ugggcggcca ggacuucaac      780

cagagacugc ugcaguaccu guacaagcag aucuaccaga ccuacggcuu cgugcccagc      840

agaaaggagg agauccacag acugagacag gccguggaga uggugaagcu gaaccugacc      900

cugcaccaga gcgcccagcu gagcgugcug cugaccgugg aggagcagga cagaaaggag      960

ccccacagca gcgacaccga gcugcccaag gacaagcuga gcagcgccga cgaccacaga     1020

gugaacagcg gcuucggcag aggccugagc gacaagaaga gcggcgagag ccaggugcug     1080

uucgagaccg agaucagcag aaagcuguuc gacacccuga acgaggaccu guuccagaag     1140

auccuggugc ccauccagca ggugcugaag gagggccacc uggagaagac cgagaucgac     1200

gagguggugc uggugggcgg cagcaccaga auccccagaa ucagacaggu gauccaggag     1260

uucuucggca aggaccccaa caccagcgug gaccccgacc uggccguggu gaccggcgug     1320

gccauccagg ccggcaucga cggcggcagc uggccccugc aggugagcgc ccuggagauc     1380

cccaacaagc accugcagaa gaccaacuuc aacuga                               1416


<210>  565
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  565
auggccgcca ucggcgugca ccugggcugc accagcgccu gcguggccgu guacaaggac       60

ggcagagccg gcgugguggc caacgacgcc ggcgacagag ugacccccgc cgugguggcc      120

uacagcgaga acgaggagau cgugggccug gccgccaagc agagcagaau cagaaacauc      180

agcaacaccg ugaugaaggu gaagcagauc cugggcagaa gcagcagcga cccccaggcc      240

cagaaguaca ucgccgagag caagugccug gugaucgaga agaacggcaa gcugagauac      300

gagaucgaca ccggcgagga gaccaaguuc gugaaccccg aggacguggc cagacugauc      360

uucagcaaga ugaaggagac cgcccacagc gugcugggca gcgacgccaa cgacguggug      420

aucaccgugc ccuucgacuu cggcgagaag cagaagaacg cccugggcga ggccgccaga      480

gccgccggcu ucaacgugcu gagacugauc cacgagccca gcgccgcccu gcuggccuac      540

ggcaucggcc aggacagccc caccggcaag agcaacaucc ugguguucaa gcugggcggc      600

accagccuga gccugagcgu gauggaggug aacagcggca ucuacagagu gcugagcacc      660

aacaccgacg acaacaucgg cggcgcccac uucaccgaga cccuggccca guaccuggcc      720

agcgaguucc agagaagcuu caagcacgac gugagaggca acgccagagc caugaugaag      780

cugaccaaca gcgccgaggu ggccaagcac agccugagca cccugggcag cgccaacugc      840

uuccuggaca gccuguacga gggccaggac uucgacugca acgugagcag agccagauuc      900

gagcugcugu gcagcccccu guucaacaag ugcaucgagg ccaucagagg ccugcuggac      960

cagaacggcu ucaccgccga cgacaucaac aagguggugc ugugcggcgg cagcagcaga     1020

auccccaagc ugcagcagcu gaucaaggac cuguuccccg ccguggagcu gcugaacagc     1080

aucccccccg acgaggugau ccccaucggc gccgccaucg aggccggcau ccugaucggc     1140

aaggagaacc ugcuggugga ggacagccug augaucgagu gcagcgccag agacauccug     1200

gugaagggcg uggacgagag cggcgccagc agauucaccg ugcuguuccc cagcggcacc     1260

ccccugcccg ccagaagaca gcacacccug caggcccccg gcagcaucag cagcgugugc     1320

cuggagcugu acgagagcga cggcaagaac agcgccaagg aggagaccaa guucgcccag     1380

guggugcugc aggaccugga caagaaggag aacggccuga gagacauccu ggccgugcug     1440

accaugaaga gagacggcag ccugcacgug accugcaccg accaggagac cggcaagugc     1500

gaggccauca gcaucgagau cgccagcuga                                      1530


<210>  566
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  566
augagcgugg ugggccugga cgugggcagc cagagcugcu acaucgccgu ggccagagcc       60

ggcggcaucg agaccaucgc caacgaguuc agcgacagau gcacccccag cgugaucagc      120

uucggcagca agaacagaac caucggcgug gccgccaaga accagcagau cacccacgcc      180

aacaacaccg ugagcaacuu caagagauuc cacggcagag ccuucaacga ccccuucauc      240

cagaaggaga aggagaaccu gagcuacgac cuggugcccc ugaagaacgg cggcgugggc      300

aucaagguga uguacauggg cgaggagcac cuguucagcg uggagcagau caccgccaug      360

cugcugacca agcugaagga gaccgccgag aacagccuga agaagcccgu gaccgacugc      420

gugaucagcg ugcccagcuu cuucaccgac gccgagagaa gaagcgugcu ggacgccgcc      480

cagaucgugg gccugaacug ccugagacug augaacgaca ugaccgccgu ggcccugaac      540

uacggcaucu acaagcagga ccugcccagc cuggacgaga agcccagaau cgugguguuc      600

guggacaugg gccacagcgc cuuccaggug agcgccugcg ccuucaacaa gggcaagcug      660

aaggugcugg gcaccgccuu cgaccccuuc cugggcggca agaacuucga cgagaagcug      720

guggagcacu ucugcgccga guucaagacc aaguacaagc uggacgccaa gagcaagauc      780

agagcccugc ugagacugua ccaggagugc gagaagcuga agaagcugau gagcagcaac      840

agcaccgacc ugccccugaa caucgagugc uucaugaacg acaaggacgu gagcggcaag      900

augaacagaa gccaguucga ggagcugugc gccgagcugc ugcagaagau cgaggugccc      960

cuguacagcc ugcuggagca gacccaccug aagguggagg acgugagcgc cguggagauc     1020

gugggcggcg ccaccagaau ccccgccgug aaggagagaa ucgccaaguu cuucggcaag     1080

gacaucagca ccacccugaa cgccgacgag gccguggcca gaggcugcgc ccugcagugc     1140

gccauccuga gccccgccuu caaggugaga gaguucagcg ugaccgacgc cgugcccuuc     1200

cccaucagcc ugaucuggaa ccacgacagc gaggacaccg agggcgugca cgagguguuc     1260

agcagaaacc acgccgcccc cuucagcaag gugcugaccu uccugagaag aggccccuuc     1320

gagcuggagg ccuucuacag cgacccccag ggcgugcccu accccgaggc caagaucggc     1380

agauucgugg ugcagaacgu gagcgcccag aaggacggcg agaagagcag agugaaggug     1440

aaggugagag ugaacaccca cggcaucuuc accaucagca ccgccagcau gguggagaag     1500

gugcccaccg aggagaacga gaugagcagc gaggccgaca uggagugccu gaaccagaga     1560

ccccccgaga accccgacac cgacaagaac gugcagcagg acaacagcga ggccggcacc     1620

cagccccagg ugcagaccga cgcccagcag accagccaga gcccccccag ccccgagcug     1680

accagcgagg agaacaagau ccccgacgcc gacaaggcca acgagaagaa gguggaccag     1740

ccccccgagg ccaagaagcc caagaucaag guggugaacg uggagcugcc caucgaggcc     1800

aaccuggugu ggcagcuggg caaggaccug cugaacaugu acaucgagac cgagggcaag     1860

augaucaugc aggacaagcu ggagaaggag agaaacgacg ccaagaacgc cguggaggag     1920

uacguguacg aguucagaga caagcugugc ggccccuacg agaaguucau cugcgagcag     1980

gaccaccaga acuuccugag acugcugacc gagaccgagg acuggcugua cgaggagggc     2040

gaggaccagg ccaagcaggc cuacguggac aagcuggagg agcugaugaa gaucggcacc     2100

cccgugaagg ugagauucca ggaggccgag gagagaccca agauguucga ggagcugggc     2160

cagagacugc agcacuacgc caagaucgcc gccgacuuca gaaacaagga cgagaaguac     2220

aaccacaucg acgagagcga gaugaagaag guggagaaga gcgugaacga ggugauggag     2280

uggaugaaca acgugaugaa cgcccaggcc aagaagagcc uggaccagga ccccguggug     2340

agagcccagg agaucaagac caagaucaag gagcugaaca acaccugcga gcccguggug     2400

acccagccca agcccaagau cgagagcccc aagcuggaga gaacccccaa cggccccaac     2460

aucgacaaga aggaggagga ccuggaggac aagaacaacu ucggcgccga gcccccccac     2520

cagaacggcg agugcuaccc caacgagaag aacagcguga acauggaccu ggacuga        2577


<210>  567
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  567
auggccgaca aggugagaag acagagaccc agaagaagag ugugcugggc ccugguggcc       60

gugcugcugg ccgaccugcu ggcccugagc gacacccugg ccgugaugag cguggaccug      120

ggcagcgaga gcaugaaggu ggccaucgug aagcccggcg ugcccaugga gaucgugcug      180

aacaaggaga gcagaagaaa gacccccgug aucgugaccc ugaaggagaa cgagagauuc      240

uucggcgaca gcgccgccag cauggccauc aagaacccca aggccacccu gagauacuuc      300

cagcaccugc ugggcaagca ggccgacaac ccccacgugg cccuguacca ggccagauuc      360

cccgagcacg agcugaccuu cgacccccag agacagaccg ugcacuucca gaucagcagc      420

cagcugcagu ucagccccga ggaggugcug ggcauggugc ugaacuacag cagaagccug      480

gccgaggacu ucgccgagca gcccaucaag gacgccguga ucaccgugcc cguguucuuc      540

aaccaggccg agagaagagc cgugcugcag gccgccagaa uggccggccu gaaggugcug      600

cagcugauca acgacaacac cgccaccgcc cugagcuacg gcguguucag aagaaaggac      660

aucaacacca ccgcccagaa caucauguuc uacgacaugg gcagcggcag caccgugugc      720

accaucguga ccuaccagau ggugaagacc aaggaggccg gcaugcagcc ccagcugcag      780

aucagaggcg ugggcuucga cagaacccug ggcggccugg agauggagcu gagacugaga      840

gagagacugg ccggccuguu caacgagcag agaaagggcc agagagccaa ggacgugaga      900

gagaacccca gagccauggc caagcugcug agagaggcca acagacugaa gaccgugcug      960

agcgccaacg ccgaccacau ggcccagauc gagggccuga uggacgacgu ggacuucaag     1020

gccaagguga ccagagugga guucgaggag cugugcgccg accuguucga gagagugccc     1080

ggccccgugc agcaggcccu gcagagcgcc gagaugagcc uggacgagau cgagcaggug     1140

auccuggugg gcggcgccac cagagugccc agagugcagg aggugcugcu gaaggccgug     1200

ggcaaggagg agcugggcaa gaacaucaac gccgacgagg ccgccgccau gggcgccgug     1260

uaccaggccg ccgcccugag caaggccuuc aaggugaagc ccuucguggu gagagacgcc     1320

gugguguacc ccauccuggu ggaguucacc agagaggugg aggaggagcc cggcauccac     1380

agccugaagc acaacaagag agugcuguuc agcagaaugg gccccuaccc ccagagaaag     1440

gugaucaccu ucaacagaua cagccacgac uucaacuucc acaucaacua cggcgaccug     1500

ggcuuccugg gccccgagga ccugagagug uucggcagcc agaaccugac caccgugaag     1560

cugaagggcg ugggcgacag cuucaagaag uaccccgacu acgagagcaa gggcaucaag     1620

gcccacuuca accuggacga gagcggcgug cugagccugg acagagugga gagcguguuc     1680

gagacccugg uggaggacag cgccgaggag gagagcaccc ugaccaagcu gggcaacacc     1740

aucagcagcc uguucggcgg cggcaccacc cccgacgcca aggagaacgg caccgacacc     1800

gugcaggagg aggaggagag ccccgccgag ggcagcaagg acgagcccgg cgagcaggug     1860

gagcugaagg aggaggccga ggcccccgug gaggacggca gccagccccc cccccccgag     1920

cccaagggcg acgccacccc cgagggcgag aaggccaccg agaaggagaa cggcgacaag     1980

agcgaggccc agaagcccag cgagaaggcc gaggccggcc ccgagggcgu ggcccccgcc     2040

cccgagggcg agaagaagca gaagcccgcc agaaagagaa gaauggugga ggagaucggc     2100

guggagcugg uggugcugga ccugcccgac cugcccgagg acaagcuggc ccagagcgug     2160

cagaagcugc aggaccugac ccugagagac cuggagaagc aggagagaga gaaggccgcc     2220

aacagccugg aggccuucau cuucgagacc caggacaagc uguaccagcc cgaguaccag     2280

gaggugagca ccgaggagca gagagaggag aucagcggca agcugagcgc cgccagcacc     2340

uggcuggagg acgagggcgu gggcgccacc accgugaugc ugaaggagaa gcuggccgag     2400

cugagaaagc ugugccaggg ccuguucuuc agaguggagg agagaaagaa guggcccgag     2460

agacugagcg cccuggacaa ccugcugaac cacagcagca uguuccugaa gggcgccaga     2520

cugauccccg agauggacca gaucuucacc gagguggaga ugaccacccu ggagaaggug     2580

aucaacgaga ccugggccug gaagaacgcc acccuggccg agcaggccaa gcugcccgcc     2640

accgagaagc ccgugcugcu gagcaaggac aucgaggcca agaugauggc ccuggacaga     2700

gaggugcagu accugcugaa caaggccaag uucaccaagc ccagacccag acccaaggac     2760

aagaacggca ccagagccga gcccccccug aacgccagcg ccagcgacca gggcgagaag     2820

gugauccccc ccgccggcca gaccgaggac gccgagccca ucagcgagcc cgagaaggug     2880

gagaccggca gcgagcccgg cgacaccgag ccccuggagc ugggcggccc cggcgccgag     2940

cccgagcaga aggagcagag caccggccag aagagacccc ugaagaacga cgagcuguga     3000


<210>  568
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  568
augcccgagg agacccagac ccaggaccag cccauggagg aggaggaggu ggagaccuuc       60

gccuuccagg ccgagaucgc ccagcugaug agccugauca ucaacaccuu cuacagcaac      120

aaggagaucu uccugagaga gcugaucagc aacagcagcg acgcccugga caagaucaga      180

uacgagagcc ugaccgaccc cagcaagcug gacagcggca aggagcugca caucaaccug      240

auccccaaca agcaggacag aacccugacc aucguggaca ccggcaucgg caugaccaag      300

gccgaccuga ucaacaaccu gggcaccauc gccaagagcg gcaccaaggc cuucauggag      360

gcccugcagg ccggcgccga caucagcaug aucggccagu ucggcguggg cuucuacagc      420

gccuaccugg uggccgagaa ggugaccgug aucaccaagc acaacgacga cgagcaguac      480

gccugggaga gcagcgccgg cggcagcuuc accgugagaa ccgacaccgg cgagcccaug      540

ggcagaggca ccaaggugau ccugcaccug aaggaggacc agaccgagua ccuggaggag      600

agaagaauca aggagaucgu gaagaagcac agccaguuca ucggcuaccc caucacccug      660

uucguggaga aggagagaga caaggaggug agcgacgacg aggccgagga gaaggaggac      720

aaggaggagg agaaggagaa ggaggagaag gagagcgagg acaagcccga gaucgaggac      780

gugggcagcg acgaggagga ggagaagaag gacggcgaca agaagaagaa gaagaagauc      840

aaggagaagu acaucgacca ggaggagcug aacaagacca agcccaucug gaccagaaac      900

cccgacgaca ucaccaacga ggaguacggc gaguucuaca agagccugac caacgacugg      960

gaggaccacc uggccgugaa gcacuucagc guggagggcc agcuggaguu cagagcccug     1020

cuguucgugc ccagaagagc ccccuucgac cuguucgaga acagaaagaa gaagaacaac     1080

aucaagcugu acgugagaag aguguucauc auggacaacu gcgaggagcu gauccccgag     1140

uaccugaacu ucaucagagg cgugguggac agcgaggacc ugccccugaa caucagcaga     1200

gagaugcugc agcagagcaa gauccugaag gugaucagaa agaaccuggu gaagaagugc     1260

cuggagcugu ucaccgagcu ggccgaggac aaggagaacu acaagaaguu cuacgagcag     1320

uucagcaaga acaucaagcu gggcauccac gaggacagcc agaacagaaa gaagcugagc     1380

gagcugcuga gauacuacac cagcgccagc ggcgacgaga uggugagccu gaaggacuac     1440

ugcaccagaa ugaaggagaa ccagaagcac aucuacuaca ucaccggcga gaccaaggac     1500

cagguggcca acagcgccuu cguggagaga cugagaaagc acggccugga ggugaucuac     1560

augaucgagc ccaucgacga guacugcgug cagcagcuga aggaguucga gggcaagacc     1620

cuggugagcg ugaccaagga gggccuggag cugcccgagg acgaggagga gaagaagaag     1680

caggaggaga agaagaccaa guucgagaac cugugcaaga ucaugaagga cauccuggag     1740

aagaaggugg agaagguggu ggugagcaac agacugguga ccagccccug cugcaucgug     1800

accagcaccu acggcuggac cgccaacaug gagagaauca ugaaggccca ggcccugaga     1860

gacaacagca ccaugggcua cauggccgcc aagaagcacc uggagaucaa ccccgaccac     1920

agcaucaucg agacccugag acagaaggcc gaggccgaca agaacgacaa gagcgugaag     1980

gaccugguga uccugcugua cgagaccgcc cugcugagca gcggcuucag ccuggaggac     2040

ccccagaccc acgccaacag aaucuacaga augaucaagc ugggccuggg caucgacgag     2100

gacgacccca ccgccgacga caccagcgcc gccgugaccg aggagaugcc cccccuggag     2160

ggcgacgacg acaccagcag aauggaggag guggacuga                            2199


<210>  569
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  569
auggacagca gcaagcugga cagcggcaag ggccugcaca ucaaccuggu gcccaacaag       60

cagaaccaga cccugaccau cguggacacc agaaucggca ugaccaagac cgaccugauc      120

aacaaccugg gcaccgugac caagagcggc accaaggccu ucauggaggc ccugcaggcc      180

gacgccgaca ucagcaugau cggccacuuc ggcgugggcu ucuacagcgc cuaccuggug      240

gccaagaagg ugaccgugau cagcaagcac aacaacgacg agcaguacac cugggagagc      300

agcgccggcg gcagcuucac cgugagaacc gacgaguga                             339


<210>  570
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  570
augcccgagg aggugcacca cggcgaggag gagguggaga ccuucgccuu ccaggccgag       60

aucgcccagc ugaugagccu gaucaucaac accuucuaca gcaacaagga gaucuuccug      120

agagagcuga ucagcaacgc cagcgacgcc cuggacaaga ucagauacga gagccugacc      180

gaccccagca agcuggacag cggcaaggag cugaagaucg acaucauccc caacccccag      240

gagagaaccc ugacccuggu ggacaccggc aucggcauga ccaaggccga ccugaucaac      300

aaccugggca ccaucgccaa gagcggcacc aaggccuuca uggaggcccu gcaggccggc      360

gccgacauca gcaugaucgg ccaguucggc gugggcuucu acagcgccua ccugguggcc      420

gagaaggugg uggugaucac caagcacaac gacgacgagc aguacgccug ggagagcagc      480

gccggcggca gcuucaccgu gagagccgac cacggcgagc ccaucggcag aggcaccaag      540

gugauccugc accugaagga ggaccagacc gaguaccugg aggagagaag agugaaggag      600

guggugaaga agcacagcca guucaucggc uaccccauca cccuguaccu ggagaaggag      660

agagagaagg agaucagcga cgacgaggcc gaggaggaga agggcgagaa ggaggaggag      720

gacaaggacg acgaggagaa gcccaagauc gaggacgugg gcagcgacga ggaggacgac      780

agcggcaagg acaagaagaa gaagaccaag aagaucaagg agaaguacau cgaccaggag      840

gagcugaaca agaccaagcc caucuggacc agaaaccccg acgacaucac ccaggaggag      900

uacggcgagu ucuacaagag ccugaccaac gacugggagg accaccuggc cgugaagcac      960

uucagcgugg agggccagcu ggaguucaga gcccugcugu ucauccccag aagagccccc     1020

uucgaccugu ucgagaacaa gaagaagaag aacaacauca agcuguacgu gagaagagug     1080

uucaucaugg acagcugcga cgagcugauc cccgaguacc ugaacuucau cagaggcgug     1140

guggacagcg aggaccugcc ccugaacauc agcagagaga ugcugcagca gagcaagauc     1200

cugaagguga ucagaaagaa caucgugaag aagugccugg agcuguucag cgagcuggcc     1260

gaggacaagg agaacuacaa gaaguucuac gaggccuuca gcaagaaccu gaagcugggc     1320

auccacgagg acagcaccaa cagaagaaga cugagcgagc ugcugagaua ccacaccagc     1380

cagagcggcg acgagaugac cagccugagc gaguacguga gcagaaugaa ggagacccag     1440

aagagcaucu acuacaucac cggcgagagc aaggagcagg uggccaacag cgccuucgug     1500

gagagaguga gaaagagagg cuucgaggug guguacauga ccgagcccau cgacgaguac     1560

ugcgugcagc agcugaagga guucgacggc aagagccugg ugagcgugac caaggagggc     1620

cuggagcugc ccgaggacga ggaggagaag aagaagaugg aggagagcaa ggccaaguuc     1680

gagaaccugu gcaagcugau gaaggagauc cuggacaaga agguggagaa ggugaccauc     1740

agcaacagac uggugagcag ccccugcugc aucgugacca gcaccuacgg cuggaccgcc     1800

aacauggaga gaaucaugaa ggcccaggcc cugagagaca acagcaccau gggcuacaug     1860

auggccaaga agcaccugga gaucaacccc gaccacccca ucguggagac ccugagacag     1920

aaggccgagg ccgacaagaa cgacaaggcc gugaaggacc ugguggugcu gcuguucgag     1980

accgcccugc ugagcagcgg cuucagccug gaggaccccc agacccacag caacagaauc     2040

uacagaauga ucaagcuggg ccugggcauc gacgaggacg agguggccgc cgaggagccc     2100

aacgccgccg ugcccgacga gauccccccc cuggagggcg acgaggacgc cagcagaaug     2160

gaggaggugg acuga                                                      2175


<210>  571
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  571
augagagccc ugugggugcu gggccugugc ugcgugcugc ugaccuucgg cagcgugaga       60

gccgacgacg agguggacgu ggacggcacc guggaggagg accugggcaa gagcagagag      120

ggcagcagaa ccgacgacga gguggugcag agagaggagg aggccaucca gcuggacggc      180

cugaacgcca gccagaucag agagcugaga gagaagagcg agaaguucgc cuuccaggcc      240

gaggugaaca gaaugaugaa gcugaucauc aacagccugu acaagaacaa ggagaucuuc      300

cugagagagc ugaucagcaa cgccagcgac gcccuggaca agaucagacu gaucagccug      360

accgacgaga acgcccugag cggcaacgag gagcugaccg ugaagaucaa gugcgacaag      420

gagaagaacc ugcugcacgu gaccgacacc ggcgugggca ugaccagaga ggagcuggug      480

aagaaccugg gcaccaucgc caagagcggc accagcgagu uccugaacaa gaugaccgag      540

gcccaggagg acggccagag caccagcgag cugaucggcc aguucggcgu gggcuucuac      600

agcgccuucc ugguggccga caaggugauc gugaccagca agcacaacaa cgacacccag      660

cacaucuggg agagcgacag caacgaguuc agcgugaucg ccgaccccag aggcaacacc      720

cugggcagag gcaccaccau cacccuggug cugaaggagg aggccagcga cuaccuggag      780

cuggacacca ucaagaaccu ggugaagaag uacagccagu ucaucaacuu ccccaucuac      840

guguggagca gcaagaccga gaccguggag gagcccaugg aggaggagga ggccgccaag      900

gaggagaagg aggagagcga cgacgaggcc gccguggagg aggaggagga ggagaagaag      960

cccaagacca agaaggugga gaagaccgug ugggacuggg agcugaugaa cgacaucaag     1020

cccaucuggc agagacccag caaggaggug gaggaggacg aguacaaggc cuucuacaag     1080

agcuucagca aggagagcga cgaccccaug gccuacaucc acuucaccgc cgagggcgag     1140

gugaccuuca agagcauccu guucgugccc accagcgccc ccagaggccu guucgacgag     1200

uacggcagca agaagagcga cuacaucaag cuguacguga gaagaguguu caucaccgac     1260

gacuuccacg acaugaugcc caaguaccug aacuucguga agggcguggu ggacagcgac     1320

gaccugcccc ugaacgugag cagagagacc cugcagcagc acaagcugcu gaaggugauc     1380

agaaagaagc uggugagaaa gacccuggac augaucaaga agaucgccga cgacaaguac     1440

aacgacaccu ucuggaagga guucggcacc aacaucaagc ugggcgugau cgaggaccac     1500

agcaacagaa ccagacuggc caagcugcug agauuccaga gcagccacca ccccaccgac     1560

aucaccagcc uggaccagua cguggagaga augaaggaga agcaggacaa gaucuacuuc     1620

auggccggca gcagcagaaa ggaggccgag agcagccccu ucguggagag acugcugaag     1680

aagggcuacg aggugaucua ccugaccgag cccguggacg aguacugcau ccaggcccug     1740

cccgaguucg acggcaagag auuccagaac guggccaagg agggcgugaa guucgacgag     1800

agcgagaaga ccaaggagag cagagaggcc guggagaagg aguucgagcc ccugcugaac     1860

uggaugaagg acaaggcccu gaaggacaag aucgagaagg ccguggugag ccagagacug     1920

accgagagcc ccugcgcccu gguggccagc caguacggcu ggagcggcaa cauggagaga     1980

aucaugaagg cccaggccua ccagaccggc aaggacauca gcaccaacua cuacgccagc     2040

cagaagaaga ccuucgagau caaccccaga cacccccuga ucagagacau gcugagaaga     2100

aucaaggagg acgaggacga caagaccgug cuggaccugg ccguggugcu guucgagacc     2160

gccacccuga gaagcggcua ccugcugccc gacaccaagg ccuacggcga cagaaucgag     2220

agaaugcuga gacugagccu gaacaucgac cccgacgcca agguggagga ggagcccgag     2280

gaggagcccg aggagaccgc cgaggacacc accgaggaca ccgagcagga cgaggacgag     2340

gagauggacg ugggcaccga cgaggaggag gagaccgcca aggagagcac cgccgagaag     2400

gacgagcugu ga                                                         2412


<210>  572
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  572
auggccagag agcugagagc ccugcugcug uggggcagaa gacugagacc ccugcugaga       60

gcccccgccc uggccgccgu gcccggcggc aagcccaucc ugugccccag aagaaccacc      120

gcccagcugg gccccagaag aaaccccgcc uggagccugc aggccggcag acuguucagc      180

acccagaccg ccgaggacaa ggaggagccc cugcacagca ucaucagcag caccgagagc      240

gugcagggca gcaccagcaa gcacgaguuc caggccgaga ccaagaagcu gcuggacauc      300

guggccagaa gccuguacag cgagaaggag guguucauca gagagcugau cagcaacgcc      360

agcgacgccc uggagaagcu gagacacaag cuggugagcg acggccaggc ccugcccgag      420

auggagaucc accugcagac caacgccgag aagggcacca ucaccaucca ggacaccggc      480

aucggcauga cccaggagga gcuggugagc aaccugggca ccaucgccag aagcggcagc      540

aaggccuucc uggacgcccu gcagaaccag gccgaggcca gcagcaagau caucggccag      600

uucggcgugg gcuucuacag cgccuucaug guggccgaca gaguggaggu guacagcaga      660

agcgccgccc ccggcagccu gggcuaccag uggcugagcg acggcagcgg cguguucgag      720

aucgccgagg ccagcggcgu gagaaccggc accaagauca ucauccaccu gaagagcgac      780

ugcaaggagu ucagcagcga ggccagagug agagacgugg ugaccaagua cagcaacuuc      840

gugagcuucc cccuguaccu gaacggcaga agaaugaaca cccugcaggc caucuggaug      900

auggacccca aggacgugag agaguggcag cacgaggagu ucuacagaua cguggcccag      960

gcccacgaca agcccagaua cacccugcac uacaagaccg acgccccccu gaacaucaga     1020

agcaucuucu acgugcccga caugaagccc agcauguucg acgugagcag agagcugggc     1080

agcagcgugg cccuguacag cagaaaggug cugauccaga ccaaggccac cgacauccug     1140

cccaaguggc ugagauucau cagaggcgug guggacagcg aggacauccc ccugaaccug     1200

agcagagagc ugcugcagga gagcgcccug aucagaaagc ugagagacgu gcugcagcag     1260

agacugauca aguucuucau cgaccagagc aagaaggacg ccgagaagua cgccaaguuc     1320

uucgaggacu acggccuguu caugagagag ggcaucguga ccgccaccga gcaggaggug     1380

aaggaggaca ucgccaagcu gcugagauac gagagcagcg cccugcccag cggccagcug     1440

accagccuga gcgaguacgc cagcagaaug agagccggca ccagaaacau cuacuaccug     1500

ugcgccccca acagacaccu ggccgagcac agccccuacu acgaggccau gaagaagaag     1560

gacaccgagg ugcuguucug cuucgagcag uucgacgagc ugacccugcu gcaccugaga     1620

gaguucgaca agaagaagcu gaucagcgug gagaccgaca ucguggugga ccacuacaag     1680

gaggagaagu ucgaggacag aagccccgcc gccgagugcc ugagcgagaa ggagaccgag     1740

gagcugaugg ccuggaugag aaacgugcug ggcagcagag ugaccaacgu gaaggugacc     1800

cugagacugg acacccaccc cgccauggug accgugcugg agaugggcgc cgccagacac     1860

uuccugagaa ugcagcagcu ggccaagacc caggaggaga gagcccagcu gcugcagccc     1920

acccuggaga ucaaccccag acacgcccug aucaagaagc ugaaccagcu gagagccagc     1980

gagcccggcc uggcccagcu gcugguggac cagaucuacg agaacgccau gaucgccgcc     2040

ggccuggugg acgaccccag agccauggug ggcagacuga acgagcugcu ggugaaggcc     2100

cuggagagac acuga                                                      2115


<210>  573
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  573
augggcaaga ucagcagccu gcccacccag cuguucaagu gcugcuucug cgacuuccug       60

aaggugaaga ugcacaccau gagcagcagc caccuguucu accuggcccu gugccugcug      120

accuucacca gcagcgccac cgccggcccc gagacccugu gcggcgccga gcugguggac      180

gcccugcagu ucgugugcgg cgacagaggc uucuacuuca acaagcccac cggcuacggc      240

agcagcagca gaagagcccc ccagaccggc aucguggacg agugcugcuu cagaagcugc      300

gaccugagaa gacuggagau guacugcgcc ccccugaagc ccgccaagag cgccagaagc      360

gugagagccc agagacacac cgacaugccc aagacccaga aggaggugca ccugaagaac      420

gccagcagag gcagcgccgg caacaagaac uacagaaugu ga                         462


<210>  574
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  574
augggcaucc ccaugggcaa gagcaugcug gugcugcuga ccuuccuggc cuucgccagc       60

ugcugcaucg ccgccuacag acccagcgag acccugugcg gcggcgagcu gguggacacc      120

cugcaguucg ugugcggcga cagaggcuuc uacuucagca gacccgccag cagagugagc      180

agaagaagca gaggcaucgu ggaggagugc ugcuucagaa gcugcgaccu ggcccugcug      240

gagaccuacu gcgccacccc cgccaagagc gagagagacg ugagcacccc ccccaccgug      300

cugcccgaca acuuccccag auaccccgug ggcaaguucu uccaguacga caccuggaag      360

cagagcaccc agagacugag aagaggccug cccgcccugc ugagagccag aagaggccac      420

gugcuggcca aggagcugga ggccuucaga gaggccaaga gacacagacc ccugaucgcc      480

cugcccaccc aggaccccgc ccacggcggc gccccccccg agauggccag caacagaaag      540

uga                                                                    543


<210>  575
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  575
augaacagcu ucagcaccag cgccuucggc cccguggccu ucagccuggg ccugcugcug       60

gugcugcccg ccgccuuccc cgcccccgug ccccccggcg aggacagcaa ggacguggcc      120

gccccccaca gacagccccu gaccagcagc gagagaaucg acaagcagau cagauacauc      180

cuggacggca ucagcgcccu gagaaaggag accugcaaca agagcaacau gugcgagagc      240

agcaaggagg cccuggccga gaacaaccug aaccugccca agauggccga gaaggacggc      300

ugcuuccaga gcggcuucaa cgaggagacc ugccugguga agaucaucac cggccugcug      360

gaguucgagg uguaccugga guaccugcag aacagauucg agagcagcga ggagcaggcc      420

agagccgugc agaugagcac caaggugcug auccaguucc ugcagaagaa ggccaagaac      480

cuggacgcca ucaccacccc cgaccccacc accaacgcca gccugcugac caagcugcag      540

gcccagaacc aguggcugca ggacaugacc acccaccuga uccugagaag cuucaaggag      600

uuccugcaga gcagccugag agcccugaga cagauguga                             639


<210>  576
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  576
augccccugc uguggcugag aggcuuccug cuggccagcu gcuggaucau cgugagaagc       60

agccccaccc ccggcagcga gggccacagc gccgcccccg acugccccag cugcgcccug      120

gccgcccugc ccaaggacgu gcccaacagc cagcccgaga ugguggaggc cgugaagaag      180

cacauccuga acaugcugca ccugaagaag agacccgacg ugacccagcc cgugcccaag      240

gccgcccugc ugaacgccau cagaaagcug cacgugggca aggugggcga gaacggcuac      300

guggagaucg aggacgacau cggcagaaga gccgagauga acgagcugau ggagcagacc      360

agcgagauca ucaccuucgc cgagagcggc accgccagaa agacccugca cuucgagauc      420

agcaaggagg gcagcgaccu gagcguggug gagagagccg agguguggcu guuccugaag      480

gugcccaagg ccaacagaac cagaaccaag gugaccauca gacuguucca gcagcagaag      540

cacccccagg gcagccugga caccggcgag gaggccgagg aggugggccu gaagggcgag      600

agaagcgagc ugcugcugag cgagaaggug guggacgcca gaaagagcac cuggcacgug      660

uuccccguga gcagcagcau ccagagacug cuggaccagg gcaagagcag ccuggacgug      720

agaaucgccu gcgagcagug ccaggagagc ggcgccagcc uggugcugcu gggcaagaag      780

aagaagaagg aggaggaggg cgagggcaag aagaagggcg gcggcgaggg cggcgccggc      840

gccgacgagg agaaggagca gagccacaga cccuuccuga ugcugcaggc cagacagagc      900

gaggaccacc cccacagaag aagaagaaga ggccuggagu gcgacggcaa ggugaacauc      960

ugcugcaaga agcaguucuu cgugagcuuc aaggacaucg gcuggaacga cuggaucauc     1020

gcccccagcg gcuaccacgc caacuacugc gagggcgagu gccccagcca caucgccggc     1080

accagcggca gcagccugag cuuccacagc accgugauca accacuacag aaugagaggc     1140

cacagccccu ucgccaaccu gaagagcugc ugcgugccca ccaagcugag acccaugagc     1200

augcuguacu acgacgacgg ccagaacauc aucaagaagg acauccagaa caugaucgug     1260

gaggagugcg gcugcagcug a                                               1281


<210>  577
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  577
auggacggcc ugcccggcag agcccugggc gccgccugcc ugcugcugcu ggccgccggc       60

uggcugggcc ccgaggccug gggcagcccc accccccccc ccacccccgc cgcccccccc      120

cccccccccc cccccggcag ccccggcggc agccaggaca ccugcaccag cugcggcggc      180

uucagaagac ccgaggagcu gggcagagug gacggcgacu uccuggaggc cgugaagaga      240

cacauccuga gcagacugca gaugagaggc agacccaaca ucacccacgc cgugcccaag      300

gccgccaugg ugaccgcccu gagaaagcug cacgccggca aggugagaga ggacggcaga      360

guggagaucc cccaccugga cggccacgcc agccccggcg ccgacggcca ggagagagug      420

agcgagauca ucagcuucgc cgagaccgac ggccuggcca gcagcagagu gagacuguac      480

uucuucauca gcaacgaggg caaccagaac cuguucgugg ugcaggccag ccuguggcug      540

uaccugaagc ugcugcccua cgugcuggag aagggcagca gaagaaaggu gagagugaag      600

guguacuucc aggagcaggg ccacggcgac agauggaaca ugguggagaa gagaguggac      660

cugaagagaa gcggcuggca caccuucccc cugaccgagg ccauccaggc ccuguucgag      720

agaggcgaga gaagacugaa ccuggacgug cagugcgaca gcugccagga gcuggccgug      780

gugcccgugu ucguggaccc cggcgaggag agccacagac ccuucguggu ggugcaggcc      840

agacugggcg acagcagaca cagaaucaga aagagaggcc uggagugcga cggcagaacc      900

aaccugugcu gcagacagca guucuucauc gacuucagac ugaucggcug gaacgacugg      960

aucaucgccc ccaccggcua cuacggcaac uacugcgagg gcagcugccc cgccuaccug     1020

gccggcgugc ccggcagcgc cagcagcuuc cacaccgccg uggugaacca guacagaaug     1080

agaggccuga accccggcac cgugaacagc ugcugcaucc ccaccaagcu gagcaccaug     1140

agcaugcugu acuucgacga cgaguacaac aucgugaaga gagacgugcc caacaugauc     1200

guggaggagu gcggcugcgc cuga                                            1224


<210>  578
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  578
auggcccuga gagugcugcu gcugaccgcc cugacccugu gccacggcuu caaccuggac       60

accgagaacg ccaugaccuu ccaggagaac gccagaggcu ucggccagag cguggugcag      120

cugcagggca gcagaguggu ggugggcgcc ccccaggaga ucguggccgc caaccagaga      180

ggcagccugu accagugcga cuacagcacc ggcagcugcg agcccaucag acugcaggug      240

cccguggagg ccgugaacau gagccugggc cugagccugg ccgccaccac cagccccccc      300

cagcugcugg ccugcggccc caccgugcac cagaccugca gcgagaacac cuacgugaag      360

ggccugugcu uccuguucgg cagcaaccug agacagcagc cccagaaguu ccccgaggcc      420

cugagaggcu gcccccagga ggacagcgac aucgccuucc ugaucgacgg cagcggcagc      480

aucauccccc acgacuucag aagaaugaag gaguucguga gcaccgugau ggagcagcug      540

aagaagagca agacccuguu cagccugaug caguacagcg aggaguucag aauccacuuc      600

accuucaagg aguuccagaa caaccccaac cccagaagcc uggugaagcc caucacccag      660

cugcugggca gaacccacac cgccaccggc aucagaaagg uggugagaga gcuguucaac      720

aucaccaacg gcgccagaaa gaacgccuuc aagauccugg uggugaucac cgacggcgag      780

aaguucggcg acccccuggg cuacgaggac gugauccccg aggccgacag agagggcgug      840

aucagauacg ugaucggcgu gggcgacgcc uucagaagcg agaagagcag acaggagcug      900

aacaccaucg ccagcaagcc ccccagagac cacguguucc aggugaacaa cuucgaggcc      960

cugaagacca uccagaacca gcugagagag aagaucuucg ccaucgaggg cacccagacc     1020

ggcagcagca gcagcuucga gcacgagaug agccaggagg gcuucagcgc cgccaucacc     1080

agcaacggcc cccugcugag caccgugggc agcuacgacu gggccggcgg cguguuccug     1140

uacaccagca aggagaagag caccuucauc aacaugacca gaguggacag cgacaugaac     1200

gacgccuacc ugggcuacgc cgccgccauc auccugagaa acagagugca gagccuggug     1260

cugggcgccc ccagauacca gcacaucggc cugguggcca uguucagaca gaacaccggc     1320

augugggaga gcaacgccaa cgugaagggc acccagaucg gcgccuacuu cggcgccagc     1380

cugugcagcg uggacgugga cagcaacggc agcaccgacc uggugcugau cggcgccccc     1440

cacuacuacg agcagaccag aggcggccag gugagcgugu gcccccugcc cagaggcaga     1500

gccagauggc agugcgacgc cgugcuguac ggcgagcagg gccagcccug gggcagauuc     1560

ggcgccgccc ugaccgugcu gggcgacgug aacggcgaca agcugaccga cguggccauc     1620

ggcgcccccg gcgaggagga caacagaggc gccguguacc uguuccacgg caccagcggc     1680

agcggcauca gccccagcca cagccagaga aucgccggca gcaagcugag ccccagacug     1740

caguacuucg gccagagccu gagcggcggc caggaccuga ccauggacgg ccugguggac     1800

cugaccgugg gcgcccaggg ccacgugcug cugcugagaa gccagcccgu gcugagagug     1860

aaggccauca uggaguucaa ccccagagag guggccagaa acguguucga gugcaacgac     1920

caggugguga agggcaagga ggccggcgag gugagagugu gccugcacgu gcagaagagc     1980

accagagaca gacugagaga gggccagauc cagagcgugg ugaccuacga ccuggcccug     2040

gacagcggca gaccccacag cagagccgug uucaacgaga ccaagaacag caccagaaga     2100

cagacccagg ugcugggccu gacccagacc ugcgagaccc ugaagcugca gcugcccaac     2160

ugcaucgagg accccgugag ccccaucgug cugagacuga acuucagccu ggugggcacc     2220

ccccugagcg ccuucggcaa ccugagaccc gugcuggccg aggacgccca gagacuguuc     2280

accgcccugu uccccuucga gaagaacugc ggcaacgaca acaucugcca ggacgaccug     2340

agcaucaccu ucagcuucau gagccuggac ugccuggugg ugggcggccc cagagaguuc     2400

aacgugaccg ugaccgugag aaacgacggc gaggacagcu acagaaccca ggugaccuuc     2460

uucuuccccc uggaccugag cuacagaaag gugagcaccc ugcagaacca gagaagccag     2520

agaagcugga gacuggccug cgagagcgcc agcagcaccg aggugagcgg cgcccugaag     2580

agcaccagcu gcagcaucaa ccaccccauc uuccccgaga acagcgaggu gaccuucaac     2640

aucaccuucg acguggacag caaggccagc cugggcaaca agcugcugcu gaaggccaac     2700

gugaccagcg agaacaacau gcccagaacc aacaagaccg aguuccagcu ggagcugccc     2760

gugaaguacg ccguguacau gguggugacc agccacggcg ugagcaccaa guaccugaac     2820

uucaccgcca gcgagaacac cagcagagug augcagcacc aguaccaggu gagcaaccug     2880

ggccagagaa gccugcccau cagccuggug uuccuggugc ccgugagacu gaaccagacc     2940

gugaucuggg acagacccca ggugaccuuc agcgagaacc ugagcagcac cugccacacc     3000

aaggagagac ugcccagcca cagcgacuuc cuggccgagc ugagaaaggc ccccguggug     3060

aacugcagca ucgccgugug ccagagaauc cagugcgaca uccccuucuu cggcauccag     3120

gaggaguuca acgccacccu gaagggcaac cugagcuucg acugguacau caagaccagc     3180

cacaaccacc ugcugaucgu gagcaccgcc gagauccugu ucaacgacag cguguucacc     3240

cugcugcccg gccagggcgc cuucgugaga agccagaccg agaccaaggu ggagcccuuc     3300

gaggugccca acccccugcc ccugaucgug ggcagcagcg ugggcggccu gcugcugcug     3360

gcccugauca ccgccgcccu guacaagcug ggcuucuuca agagacagua caaggacaug     3420

augagcgagg gcggcccccc cggcgccgag ccccaguga                            3459


<210>  579
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  579
auguucagcc ugaagacccu gcccuuccug cugcugcugc acgugcagau cagcaaggcc       60

uuccccguga gcagcaagga gaagaacacc aagaccgugc aggacuaccu ggagaaguuc      120

uaccagcugc ccagcaacca guaccagagc accagaaaga acggcaccaa cgugaucgug      180

gagaagcuga aggagaugca gagauucuuc ggccugaacg ugaccggcaa gcccaacgag      240

gagacccugg acaugaugaa gaagcccaga ugcggcgugc ccgacagcgg cggcuucaug      300

cugacccccg gcaaccccaa gugggagaga accaaccuga ccuacagaau cagaaacuac      360

accccccagc ugagcgaggc cgagguggag agagccauca aggacgccuu cgagcugugg      420

agcguggcca gcccccugau cuucaccaga aucagccagg gcgaggccga caucaacauc      480

gccuucuacc agagagacca cggcgacaac agccccuucg acggccccaa cggcauccug      540

gcccacgccu uccagcccgg ccagggcauc ggcggcgacg cccacuucga cgccgaggag      600

accuggacca acaccagcgc caacuacaac cuguuccugg uggccgccca cgaguucggc      660

cacagccugg gccuggccca cagcagcgac cccggcgccc ugauguaccc caacuacgcc      720

uucagagaga ccagcaacua cagccugccc caggacgaca ucgacggcau ccaggccauc      780

uacggccuga gcagcaaccc cauccagccc accggcccca gcacccccaa gcccugcgac      840

cccagccuga ccuucgacgc caucaccacc cugagaggcg agauccuguu cuucaaggac      900

agauacuucu ggagaagaca cccccagcug cagagagugg agaugaacuu caucagccug      960

uucuggccca gccugcccac cggcauccag gccgccuacg aggacuucga cagagaccug     1020

aucuuccugu ucaagggcaa ccaguacugg gcccugagcg gcuacgacau ccugcagggc     1080

uaccccaagg acaucagcaa cuacggcuuc cccagcagcg ugcaggccau cgacgccgcc     1140

guguucuaca gaagcaagac cuacuucuuc gugaacgacc aguucuggag auacgacaac     1200

cagagacagu ucauggagcc cggcuacccc aagagcauca gcggcgccuu ccccggcauc     1260

gagagcaagg uggacgccgu guuccagcag gagcacuucu uccacguguu cagcggcccc     1320

agauacuacg ccuucgaccu gaucgcccag agagugacca gaguggccag aggcaacaag     1380

uggcugaacu gcagauacgg cuga                                            1404


<210>  580
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  580
augagccugu ggcagccccu ggugcuggug cugcuggugc ugggcugcug cuucgccgcc       60

cccagacaga gacagagcac ccuggugcug uuccccggcg accugagaac caaccugacc      120

gacagacagc uggccgagga guaccuguac agauacggcu acaccagagu ggccgagaug      180

agaggcgaga gcaagagccu gggccccgcc cugcugcugc ugcagaagca gcugagccug      240

cccgagaccg gcgagcugga cagcgccacc cugaaggcca ugagaacccc cagaugcggc      300

gugcccgacc ugggcagauu ccagaccuuc gagggcgacc ugaaguggca ccaccacaac      360

aucaccuacu ggauccagaa cuacagcgag gaccugccca gagccgugau cgacgacgcc      420

uucgccagag ccuucgcccu guggagcgcc gugacccccc ugaccuucac cagaguguac      480

agcagagacg ccgacaucgu gauccaguuc ggcguggccg agcacggcga cggcuacccc      540

uucgacggca aggacggccu gcuggcccac gccuuccccc ccggccccgg cauccagggc      600

gacgcccacu ucgacgacga cgagcugugg agccugggca agggcguggu ggugcccacc      660

agauucggca acgccgacgg cgccgccugc cacuuccccu ucaucuucga gggcagaagc      720

uacagcgccu gcaccaccga cggcagaagc gacggccugc ccuggugcag caccaccgcc      780

aacuacgaca ccgacgacag auucggcuuc ugccccagcg agagacugua cacccaggac      840

ggcaacgccg acggcaagcc cugccaguuc cccuucaucu uccagggcca gagcuacagc      900

gccugcacca ccgacggcag aagcgacggc uacagauggu gcgccaccac cgccaacuac      960

gacagagaca agcuguucgg cuucugcccc accagagccg acagcaccgu gaugggcggc     1020

aacagcgccg gcgagcugug cguguucccc uucaccuucc ugggcaagga guacagcacc     1080

ugcaccagcg agggcagagg cgacggcaga cuguggugcg ccaccaccag caacuucgac     1140

agcgacaaga aguggggcuu cugccccgac cagggcuaca gccuguuccu gguggccgcc     1200

cacgaguucg gccacgcccu gggccuggac cacagcagcg ugcccgaggc ccugauguac     1260

cccauguaca gauucaccga gggccccccc cugcacaagg acgacgugaa cggcaucaga     1320

caccuguacg gccccagacc cgagcccgag cccagacccc ccaccaccac caccccccag     1380

cccaccgccc cccccaccgu gugccccacc ggccccccca ccgugcaccc cagcgagaga     1440

cccaccgccg gccccaccgg cccccccagc gccggcccca ccggcccccc caccgccggc     1500

cccagcaccg ccaccaccgu gccccugagc cccguggacg acgccugcaa cgugaacauc     1560

uucgacgcca ucgccgagau cggcaaccag cuguaccugu ucaaggacgg caaguacugg     1620

agauucagcg agggcagagg cagcagaccc cagggccccu uccugaucgc cgacaagugg     1680

cccgcccugc ccagaaagcu ggacagcgug uucgaggaga gacugagcaa gaagcuguuc     1740

uucuucagcg gcagacaggu guggguguac accggcgcca gcgugcuggg ccccagaaga     1800

cuggacaagc ugggccuggg cgccgacgug gcccagguga ccggcgcccu gagaagcggc     1860

agaggcaaga ugcugcuguu cagcggcaga agacugugga gauucgacgu gaaggcccag     1920

augguggacc ccagaagcgc cagcgaggug gacagaaugu uccccggcgu gccccuggac     1980

acccacgacg uguuccagua cagagagaag gccuacuucu gccaggacag auucuacugg     2040

agagugagca gcagaagcga gcugaaccag guggaccagg ugggcuacgu gaccuacgac     2100

auccugcagu gccccgagga cuga                                            2124


<210>  581
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  581
augcaccccg gcgugcuggc cgccuuccug uuccugagcu ggacccacug cagagcccug       60

ccccugccca gcggcggcga cgaggacgac cugagcgagg aggaccugca guucgccgag      120

agauaccuga gaagcuacua ccaccccacc aaccuggccg gcauccugaa ggagaacgcc      180

gccagcagca ugaccgagag acugagagag augcagagcu ucuucggccu ggaggugacc      240

ggcaagcugg acgacaacac ccuggacgug augaagaagc ccagaugcgg cgugcccgac      300

gugggcgagu acaacguguu ccccagaacc cugaagugga gcaagaugaa ccugaccuac      360

agaaucguga acuacacccc cgacaugacc cacagcgagg uggagaaggc cuucaagaag      420

gccuucaagg uguggagcga cgugaccccc cugaacuuca ccagacugca cgacggcauc      480

gccgacauca ugaucagcuu cggcaucaag gagcacggcg acuucuaccc cuucgacggc      540

cccagcggcc ugcuggccca cgccuucccc cccggcccca acuacggcgg cgacgcccac      600

uucgacgacg acgagaccug gaccagcagc agcaagggcu acaaccuguu ccugguggcc      660

gcccacgagu ucggccacag ccugggccug gaccacagca aggaccccgg cgcccugaug      720

uuccccaucu acaccuacac cggcaagagc cacuucaugc ugcccgacga cgacgugcag      780

ggcauccaga gccuguacgg ccccggcgac gaggacccca accccaagca ccccaagacc      840

cccgacaagu gcgaccccag ccugagccug gacgccauca ccagccugag aggcgagacc      900

augaucuuca aggacagauu cuucuggaga cugcaccccc agcaggugga cgccgagcug      960

uuccugacca agagcuucug gcccgagcug cccaacagaa ucgacgccgc cuacgagcac     1020

cccagccacg accugaucuu caucuucaga ggcagaaagu ucugggcccu gaacggcuac     1080

gacauccugg agggcuaccc caagaagauc agcgagcugg gccugcccaa ggaggugaag     1140

aagaucagcg ccgccgugca cuucgaggac accggcaaga cccugcuguu cagcggcaac     1200

caggugugga gauacgacga caccaaccac aucauggaca aggacuaccc cagacugauc     1260

gaggaggacu uccccggcau cggcgacaag guggacgccg uguacgagaa gaacggcuac     1320

aucuacuucu ucaacggccc cauccaguuc gaguacagca ucuggagcaa cagaaucgug     1380

agagugaugc ccgccaacag cauccugugg ugcuga                               1416


<210>  582
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  582
auggagaccc ccaacaccac cgaggacuac gacaccacca ccgaguucga cuacggcgac       60

gccacccccu gccagaaggu gaacgagaga gccuucggcg cccagcugcu gcccccccug      120

uacagccugg uguucgugau cggccuggug ggcaacaucc ugguggugcu ggugcuggug      180

caguacaaga gacugaagaa caugaccagc aucuaccugc ugaaccuggc caucagcgac      240

cugcuguucc uguucacccu gcccuucugg aucgacuaca agcugaagga cgacugggug      300

uucggcgacg ccaugugcaa gauccugagc ggcuucuacu acaccggccu guacagcgag      360

aucuucuuca ucauccugcu gaccaucgac agauaccugg ccaucgugca cgccguguuc      420

gcccugagag ccagaaccgu gaccuucggc gugaucacca gcaucaucau cugggcccug      480

gccauccugg ccagcaugcc cggccuguac uucagcaaga cccaguggga guucacccac      540

cacaccugca gccugcacuu cccccacgag agccugagag aguggaagcu guuccaggcc      600

cugaagcuga accuguucgg ccuggugcug ccccugcugg ugaugaucau cugcuacacc      660

ggcaucauca agauccugcu gagaagaccc aacgagaaga agagcaaggc cgugagacug      720

aucuucguga ucaugaucau cuucuuccug uucuggaccc ccuacaaccu gaccauccug      780

aucagcgugu uccaggacuu ccuguucacc cacgagugcg agcagagcag acaccuggac      840

cuggccgugc aggugaccga ggugaucgcc uacacccacu gcugcgugaa ccccgugauc      900

uacgccuucg ugggcgagag auucagaaag uaccugagac agcuguucca cagaagagug      960

gccgugcacc uggugaagug gcugcccuuc cugagcgugg acagacugga gagagugagc     1020

agcaccagcc ccagcaccgg cgagcacgag cugagcgccg gcuucuga                  1068


<210>  583
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  583
augagaaccc uggccugccu gcugcugcug ggcugcggcu accuggccca cgugcuggcc       60

gaggaggccg agauccccag agaggugauc gagagacugg ccagaagcca gauccacagc      120

aucagagacc ugcagagacu gcuggagauc gacagcgugg gcagcgagga cagccuggac      180

accagccuga gagcccacgg cgugcacgcc accaagcacg ugcccgagaa gagaccccug      240

cccaucagaa gaaagagaag caucgaggag gccgugcccg ccgugugcaa gaccagaacc      300

gugaucuacg agauccccag aagccaggug gaccccacca gcgccaacuu ccugaucugg      360

ccccccugcg uggaggugaa gagaugcacc ggcugcugca acaccagcag cgugaagugc      420

cagcccagca gagugcacca cagaagcgug aagguggcca agguggagua cgugagaaag      480

aagcccaagc ugaaggaggu gcaggugaga cuggaggagc accuggagug cgccugcgcc      540

accaccagcc ugaaccccga cuacagagag gaggacaccg gcagacccag agagagcggc      600

aagaagagaa agagaaagag acugaagccc accuga                                636


<210>  584
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  584
augaacagau gcugggcccu guuccugagc cugugcugcu accugagacu ggugagcgcc       60

gagggcgacc ccauccccga ggagcuguac gagaugcuga gcgaccacag caucagaagc      120

uucgacgacc ugcagagacu gcugcacggc gaccccggcg aggaggacgg cgccgagcug      180

gaccugaaca ugaccagaag ccacagcggc ggcgagcugg agagccuggc cagaggcaga      240

agaagccugg gcagccugac caucgccgag cccgccauga ucgccgagug caagaccaga      300

accgaggugu ucgagaucag cagaagacug aucgacagaa ccaacgccaa cuuccuggug      360

uggccccccu gcguggaggu gcagagaugc agcggcugcu gcaacaacag aaacgugcag      420

ugcagaccca cccaggugca gcugagaccc gugcagguga gaaagaucga gaucgugaga      480

aagaagccca ucuucaagaa ggccaccgug acccuggagg accaccuggc cugcaagugc      540

gagaccgugg ccgccgccag acccgugacc agaagccccg gcggcagcca ggagcagaga      600

gccaagaccc cccagaccag agugaccauc agaaccguga gagugagaag accccccaag      660

ggcaagcaca gaaaguucaa gcacacccac gacaagaccg cccugaagga gacccugggc      720

gccuga                                                                 726


<210>  585
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  585
augagccugu ucggccugcu gcugcugacc agcgcccugg ccggccagag acagggcacc       60

caggccgaga gcaaccugag cagcaaguuc caguucagca gcaacaagga gcagaacggc      120

gugcaggacc cccagcacga gagaaucauc accgugagca ccaacggcag cauccacagc      180

cccagauucc cccacaccua ccccagaaac accgugcugg uguggagacu gguggccgug      240

gaggagaacg uguggaucca gcugaccuuc gacgagagau ucggccugga ggaccccgag      300

gacgacaucu gcaaguacga cuucguggag guggaggagc ccagcgacgg caccauccug      360

ggcagauggu gcggcagcgg caccgugccc ggcaagcaga ucagcaaggg caaccagauc      420

agaaucagau ucgugagcga cgaguacuuc cccagcgagc ccggcuucug cauccacuac      480

aacaucguga ugccccaguu caccgaggcc gugagcccca gcgugcugcc ccccagcgcc      540

cugccccugg accugcugaa caacgccauc accgccuuca gcacccugga ggaccugauc      600

agauaccugg agcccgagag auggcagcug gaccuggagg accuguacag acccaccugg      660

cagcugcugg gcaaggccuu cguguucggc agaaagagca gaguggugga ccugaaccug      720

cugaccgagg aggugagacu guacagcugc acccccagaa acuucagcgu gagcaucaga      780

gaggagcuga agagaaccga caccaucuuc uggcccggcu gccugcuggu gaagagaugc      840

ggcggcaacu gcgccugcug ccugcacaac ugcaacgagu gccagugcgu gcccagcaag      900

gugaccaaga aguaccacga ggugcugcag cugagaccca agaccggcgu gagaggccug      960

cacaagagcc ugaccgacgu ggcccuggag caccacgagg agugcgacug cgugugcaga     1020

ggcagcaccg gcggcuga                                                   1038


<210>  586
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  586
augcacagac ugaucuucgu guacacccug aucugcgcca acuucugcag cugcagagac       60

accagcgcca ccccccagag cgccagcauc aaggcccuga gaaacgccaa ccugagaaga      120

gacgaccugu acagaagaga cgagaccauc caggugaagg gcaacggcua cgugcagagc      180

cccagauucc ccaacagcua ccccagaaac cugcugcuga ccuggagacu gcacagccag      240

gagaacacca gaauccagcu gguguucgac aaccaguucg gccuggagga ggccgagaac      300

gacaucugca gauacgacuu cguggaggug gaggacauca gcgagaccag caccaucauc      360

agaggcagau ggugcggcca caaggaggug ccccccagaa ucaagagcag aaccaaccag      420

aucaagauca ccuucaagag cgacgacuac uucguggcca agcccggcuu caagaucuac      480

uacagccugc uggaggacuu ccagcccgcc gccgccagcg agaccaacug ggagagcgug      540

accagcagca ucagcggcgu gagcuacaac agccccagcg ugaccgaccc cacccugauc      600

gccgacgccc uggacaagaa gaucgccgag uucgacaccg uggaggaccu gcugaaguac      660

uucaaccccg agagcuggca ggaggaccug gagaacaugu accuggacac ccccagauac      720

agaggcagaa gcuaccacga cagaaagagc aagguggacc uggacagacu gaacgacgac      780

gccaagagau acagcugcac ccccagaaac uacagcguga acaucagaga ggagcugaag      840

cuggccaacg ugguguucuu ccccagaugc cugcuggugc agagaugcgg cggcaacugc      900

ggcugcggca ccgugaacug gagaagcugc accugcaaca gcggcaagac cgugaagaag      960

uaccacgagg ugcugcaguu cgagcccggc cacaucaaga gaagaggcag agccaagacc     1020

auggcccugg uggacaucca gcuggaccac cacgagagau gcgacugcau cugcagcagc     1080

agacccccca gauga                                                      1095


<210>  587
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  587
auggugaccc acagcaaguu ccccgccgcc ggcaugagca gaccccugga caccagccug       60

agacugaaga ccuucagcag caagagcgag uaccagcugg uggugaacgc cgugagaaag      120

cugcaggaga gcggcuucua cuggagcgcc gugaccggcg gcgaggccaa ccugcugcug      180

agcgccgagc ccgccggcac cuuccugauc agagacagca gcgaccagag acacuucuuc      240

acccugagcg ugaagaccca gagcggcacc aagaaccuga gaauccagug cgagggcggc      300

agcuucagcc ugcagagcga ccccagaagc acccagcccg ugcccagauu cgacugcgug      360

cugaagcugg ugcaccacua caugcccccc cccggcgccc ccagcuuccc cagccccccc      420

accgagccca gcagcgaggu gcccgagcag cccagcgccc agccccugcc cggcagcccc      480

cccagaagag ccuacuacau cuacagcggc ggcgagaaga ucccccuggu gcugagcaga      540

ccccugagca gcaacguggc cacccugcag caccugugca gaaagaccgu gaacggccac      600

cuggacagcu acgagaaggu gacccagcug cccggcccca ucagagaguu ccuggaccag      660

uacgacgccc cccuguga                                                    678


<210>  588
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  588
auggugccca gcgccggcca gcuggcccug uucgcccugg gcaucgugcu ggccgccugc       60

caggcccugg agaacagcac cagcccccug agcgccgacc cccccguggc cgccgccgug      120

gugagccacu ucaacgacug ccccgacagc cacacccagu ucugcuucca cggcaccugc      180

agauuccugg ugcaggagga caagcccgcc ugcgugugcc acagcggcua cgugggcgcc      240

agaugcgagc acgccgaccu gcuggccgug guggccgcca gccagaagaa gcaggccauc      300

accgcccugg ugguggugag caucguggcc cuggccgugc ugaucaucac cugcgugcug      360

auccacugcu gccaggugag aaagcacugc gaguggugca gagcccugau cugcagacac      420

gagaagccca gcgcccugcu gaagggcaga accgccugcu gccacagcga gaccguggug      480

uga                                                                    483


<210>  589
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  589
augcccccca gcggccugag acugcugccc cugcugcugc cccugcugug gcugcuggug       60

cugacccccg gcagacccgc cgccggccug agcaccugca agaccaucga cauggagcug      120

gugaagagaa agagaaucga ggccaucaga ggccagaucc ugagcaagcu gagacuggcc      180

agccccccca gccagggcga ggugcccccc ggcccccugc ccgaggccgu gcuggcccug      240

uacaacagca ccagagacag aguggccggc gagagcgccg agcccgagcc cgagcccgag      300

gccgacuacu acgccaagga ggugaccaga gugcugaugg uggagaccca caacgagauc      360

uacgacaagu ucaagcagag cacccacagc aucuacaugu ucuucaacac cagcgagcug      420

agagaggccg ugcccgagcc cgugcugcug agcagagccg agcugagacu gcugagacug      480

aagcugaagg uggagcagca cguggagcug uaccagaagu acagcaacaa cagcuggaga      540

uaccugagca acagacugcu ggcccccagc gacagccccg aguggcugag cuucgacgug      600

accggcgugg ugagacagug gcugagcaga ggcggcgaga ucgagggcuu cagacugagc      660

gcccacugca gcugcgacag cagagacaac acccugcagg uggacaucaa cggcuucacc      720

accggcagaa gaggcgaccu ggccaccauc cacggcauga acagacccuu ccugcugcug      780

auggccaccc cccuggagag agcccagcac cugcagagca gcagacacag aagagcccug      840

gacaccaacu acugcuucag cagcaccgag aagaacugcu gcgugagaca gcuguacauc      900

gacuucagaa aggaccuggg cuggaagugg auccacgagc ccaagggcua ccacgccaac      960

uucugccugg gccccugccc cuacaucugg agccuggaca cccaguacag caaggugcug     1020

gcccuguaca accagcacaa ccccggcgcc agcgccgccc ccugcugcgu gccccaggcc     1080

cuggagcccc ugcccaucgu guacuacgug ggcagaaagc ccaaggugga gcagcugagc     1140

aacaugaucg ugagaagcug caagugcagc uga                                  1173


<210>  590
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  590
augcacuacu gcgugcugag cgccuuccug auccugcacc uggugaccgu ggcccugagc       60

cugagcaccu gcagcacccu ggacauggac caguucauga gaaagagaau cgaggccauc      120

agaggccaga uccugagcaa gcugaagcug accagccccc ccgaggacua ccccgagccc      180

gaggaggugc cccccgaggu gaucagcauc uacaacagca ccagagaccu gcugcaggag      240

aaggccagca gaagagccgc cgccugcgag agagagagaa gcgacgagga guacuacgcc      300

aaggaggugu acaagaucga caugcccccc uucuucccca gcgagaacgc cauccccccc      360

accuucuaca gacccuacuu cagaaucgug agauucgacg ugagcgccau ggagaagaac      420

gccagcaacc uggugaaggc cgaguucaga guguucagac ugcagaaccc caaggccaga      480

gugcccgagc agagaaucga gcuguaccag auccugaaga gcaaggaccu gaccagcccc      540

acccagagau acaucgacag caagguggug aagaccagag ccgagggcga guggcugagc      600

uucgacguga ccgacgccgu gcacgagugg cugcaccaca aggacagaaa ccugggcuuc      660

aagaucagcc ugcacugccc cugcugcacc uucgugccca gcaacaacua caucaucccc      720

aacaagagcg aggagcugga ggccagauuc gccggcaucg acggcaccag caccuacacc      780

agcggcgacc agaagaccau caagagcacc agaaagaaga acagcggcaa gaccccccac      840

cugcugcuga ugcugcugcc cagcuacaga cuggagagcc agcagaccaa cagaagaaag      900

aagagagccc uggacgccgc cuacugcuuc agaaacgugc aggacaacug cugccugaga      960

ccccuguaca ucgacuucaa gagagaccug ggcuggaagu ggauccacga gcccaagggc     1020

uacaacgcca acuucugcgc cggcgccugc cccuaccugu ggagcagcga cacccagcac     1080

agcagagugc ugagccugua caacaccauc aaccccgagg ccagcgccag ccccugcugc     1140

gugagccagg accuggagcc ccugaccauc cuguacuaca ucggcaagac ccccaagauc     1200

gagcagcuga gcaacaugau cgugaagagc ugcaagugca gcuga                     1245


<210>  591
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  591
augaagaugc accugcagag agcccuggug gugcuggccc ugcugaacuu cgccaccgug       60

agccugagcc ugagcaccug caccacccug gacuucggcc acaucaagaa gaagagagug      120

gaggccauca gaggccagau ccugagcaag cugagacuga ccagcccccc cgagcccacc      180

gugaugaccc acgugcccua ccaggugcug gcccuguaca acagcaccag agagcugcug      240

gaggagaugc acggcgagag agaggagggc ugcacccagg agaacaccga gagcgaguac      300

uacgccaagg agauccacaa guucgacaug auccagggcc uggccgagca caacgagcug      360

gccgugugcc ccaagggcau caccagcaag guguucagau ucaacgugag cagcguggag      420

aagaacagaa ccaaccuguu cagagccgag uucagagugc ugagagugcc caaccccagc      480

agcaagagaa acgagcagag aaucgagcug uuccagaucc ugagacccga cgagcacauc      540

gccaagcaga gauacaucgg cggcaagaac cugcccacca gaggcaccgc cgaguggcug      600

agcuucgacg ugaccgacac cgugagagag uggcugcuga gaagagagag caaccugggc      660

cuggagauca gcauccacug ccccugccac accuuccagc ccaacggcga cauccuggag      720

aacauccacg aggugaugga gaucaaguuc aagggcgugg acaacgagga cgaccacggc      780

agaggcgacc ugggcagacu gaagaagcag aaggaccacc acaaccccca ccugauccug      840

augaugaucc ccccccacag acuggacaac cccggccagg gcggccagag aaagaagaga      900

gcccuggaca ccaacuacug cuucagaaac cuggaggaga acugcugcgu gagaccccug      960

uacaucgacu ucagacagga ccugggcugg aagugggugc acgagcccaa gggcuacuac     1020

gccaacuucu gcagcggccc cugccccuac cugagaagcg ccgacaccac ccacagcacc     1080

gugcugggcc uguacaacac ccugaacccc gaggccagcg ccagccccug cugcgugccc     1140

caggaccugg agccccugac cauccuguac uacgugggca gaacccccaa gguggagcag     1200

cugagcaaca ugguggugaa gagcugcaag ugcagcuga                            1239


<210>  592
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  592
auggcccccg uggccgugug ggccgcccug gccgugggcc uggagcugug ggccgccgcc       60

cacgcccugc ccgcccaggu ggccuucacc cccuacgccc ccgagcccgg cagcaccugc      120

agacugagag aguacuacga ccagaccgcc cagaugugcu gcagcaagug cagccccggc      180

cagcacgcca agguguucug caccaagacc agcgacaccg ugugcgacag cugcgaggac      240

agcaccuaca cccagcugug gaacugggug cccgagugcc ugagcugcgg cagcagaugc      300

agcagcgacc agguggagac ccaggccugc accagagagc agaacagaau cugcaccugc      360

agacccggcu gguacugcgc ccugagcaag caggagggcu gcagacugug cgccccccug      420

agaaagugca gacccggcuu cggcguggcc agacccggca ccgagaccag cgacguggug      480

ugcaagcccu gcgcccccgg caccuucagc aacaccacca gcagcaccga caucugcaga      540

ccccaccaga ucugcaacgu gguggccauc cccggcaacg ccagcaugga cgccgugugc      600

accagcacca gccccaccag aagcauggcc cccggcgccg ugcaccugcc ccagcccgug      660

agcaccagaa gccagcacac ccagcccacc cccgagccca gcaccgcccc cagcaccagc      720

uuccugcugc ccaugggccc cagccccccc gccgagggca gcaccggcga cuucgcccug      780

cccgugggcc ugaucguggg cgugaccgcc cugggccugc ugaucaucgg cguggugaac      840

ugcgugauca ugacccaggu gaagaagaag ccccugugcc ugcagagaga ggccaaggug      900

ccccaccugc ccgccgacaa ggccagaggc acccagggcc ccgagcagca gcaccugcug      960

aucaccgccc ccagcagcag cagcagcagc cuggagagca gcgccagcgc ccuggacaga     1020

agagccccca ccagaaacca gccccaggcc cccggcgugg aggccagcgg cgccggcgag     1080

gccagagcca gcaccggcag cagcgacagc agccccggcg gccacggcac ccaggugaac     1140

gugaccugca ucgugaacgu gugcagcagc agcgaccaca gcagccagug cagcagccag     1200

gccagcagca ccaugggcga caccgacagc agccccagcg agagccccaa ggacgagcag     1260

gugcccuuca gcaaggagga gugcgccuuc agaagccagc uggagacccc cgagacccug     1320

cugggcagca ccgaggagaa gccccugccc cugggcgugc ccgacgccgg caugaagccc     1380

agcuga                                                                1386


<210>  593
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  593
augcccguga ugagacuguu ccccugcuuc cugcagcugc uggccggccu ggcccugccc       60

gccgugcccc cccagcagug ggcccugagc gccggcaacg gcagcagcga gguggaggug      120

gugcccuucc aggaggugug gggcagaagc uacugcagag cccuggagag acugguggac      180

guggugagcg aguaccccag cgagguggag cacauguuca gccccagcug cgugagccug      240

cugagaugca ccggcugcug cggcgacgag aaccugcacu gcgugcccgu ggagaccgcc      300

aacgugacca ugcagcugcu gaagaucaga agcggcgaca gacccagcua cguggagcug      360

accuucagcc agcacgugag augcgagugc agaccccuga gagagaagau gaagcccgag      420

agaagaagac ccaagggcag aggcaagaga agaagagaga agcagagacc caccgacugc      480

caccugugcg gcgacgccgu gcccagaaga uga                                   513


<210>  594
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  594
augaccgaca gacagaccga caccgccccc agccccagcu accaccugcu gcccggcaga       60

agaagaaccg uggacgccgc cgccagcaga ggccagggcc ccgagcccgc ccccggcggc      120

ggcguggagg gcgugggcgc cagaggcgug gcccugaagc uguucgugca gcugcugggc      180

ugcagcagau ucggcggcgc cguggugaga gccggcgagg ccgagcccag cggcgccgcc      240

agaagcgcca gcagcggcag agaggagccc cagcccgagg agggcgagga ggaggaggag      300

aaggaggagg agagaggccc ccaguggaga cugggcgcca gaaagcccgg cagcuggacc      360

ggcgaggccg ccgugugcgc cgacagcgcc cccgccgcca gagcccccca ggcccuggcc      420

agagccagcg gcagaggcgg cagaguggcc agaagaggcg ccgaggagag cggccccccc      480

cacagcccca gcagaagagg cagcgccagc agagccggcc ccggcagagc cagcgagacc      540

augaacuucc ugcugagcug ggugcacugg agccuggccc ugcugcugua ccugcaccac      600

gccaagugga gccaggccgc ccccauggcc gagggcggcg gccagaacca ccacgaggug      660

gugaaguuca uggacgugua ccagagaagc uacugccacc ccaucgagac ccugguggac      720

aucuuccagg aguaccccga cgagaucgag uacaucuuca agcccagcug cgugccccug      780

augagaugcg gcggcugcug caacgacgag ggccuggagu gcgugcccac cgaggagagc      840

aacaucacca ugcagaucau gagaaucaag ccccaccagg gccagcacau cggcgagaug      900

agcuuccugc agcacaacaa gugcgagugc agacccaaga aggacagagc cagacaggag      960

aagaagagcg ugagaggcaa gggcaagggc cagaagagaa agagaaagaa gagcagauac     1020

aagagcugga gcguguacgu gggcgccaga ugcugccuga ugcccuggag ccugcccggc     1080

ccccaccccu gcggccccug cagcgagaga agaaagcacc uguucgugca ggacccccag     1140

accugcaagu gcagcugcaa gaacaccgac agcagaugca aggccagaca gcuggagcug     1200

aacgagagaa ccugcagaug cgacaagccc agaagauga                            1239


<210>  595
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  595
augaacuucc ugcugagcug ggugcacugg agccuggccc ugcugcugua ccugcaccac       60

gccaagugga gccaggccgc ccccauggcc gagggcggcg gccagaacca ccacgaggug      120

gugaaguuca uggacgugua ccagagaagc uacugccacc ccaucgagac ccugguggac      180

aucuuccagg aguaccccga cgagaucgag uacaucuuca agcccagcug cgugccccug      240

augagaugcg gcggcugcug caacgacgag ggccuggagu gcgugcccac cgaggagagc      300

aacaucacca ugcagaucau gagaaucaag ccccaccagg gccagcacau cggcgagaug      360

agcuuccugc agcacaacaa gugcgagugc agacccaaga aggacagagc cagacaggag      420

aagaagagcg ugagaggcaa gggcaagggc cagaagagaa agagaaagaa gagcagauac      480

aagagcugga gcguguacgu gggcgccaga ugcugccuga ugcccuggag ccugcccggc      540

ccccaccccu gcggccccug cagcgagaga agaaagcacc uguucgugca ggacccccag      600

accugcaagu gcagcugcaa gaacaccgac agcagaugca aggccagaca gcuggagcug      660

aacgagagaa ccugcagaug cgacaagccc agaagauga                             699


<210>  596
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  596
augagccccc ugcugagaag acugcugcug gccgcccugc ugcagcuggc ccccgcccag       60

gcccccguga gccagcccga cgcccccggc caccagagaa agguggugag cuggaucgac      120

guguacacca gagccaccug ccagcccaga gagguggugg ugccccugac cguggagcug      180

augggcaccg uggccaagca gcuggugccc agcugcguga ccgugcagag augcggcggc      240

ugcugccccg acgacggccu ggagugcgug cccaccggcc agcaccaggu gagaaugcag      300

auccugauga ucagauaccc cagcagccag cugggcgaga ugagccugga ggagcacagc      360

cagugcgagu gcagacccaa gaagaaggac agcgccguga agcccgacag agccgccacc      420

ccccaccaca gaccccagcc cagaagcgug cccggcuggg acagcgcccc cggcgccccc      480

agccccgccg acaucaccca ccccaccccc gcccccggcc ccagcgccca cgccgccccc      540

agcaccacca gcgcccugac ccccggcccc gccgccgccg ccgccgacgc cgccgccagc      600

agcguggcca agggcggcgc cuga                                             624


<210>  597
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  597
augcaccugc ugggcuucuu cagcguggcc ugcagccugc uggccgccgc ccugcugccc       60

ggccccagag aggcccccgc cgccgccgcc gccuucgaga gcggccugga ccugagcgac      120

gccgagcccg acgccggcga ggccaccgcc uacgccagca aggaccugga ggagcagcug      180

agaagcguga gcagcgugga cgagcugaug accgugcugu accccgagua cuggaagaug      240

uacaagugcc agcugagaaa gggcggcugg cagcacaaca gagagcaggc caaccugaac      300

agcagaaccg aggagaccau caaguucgcc gccgcccacu acaacaccga gauccugaag      360

agcaucgaca acgaguggag aaagacccag ugcaugccca gagaggugug caucgacgug      420

ggcaaggagu ucggcguggc caccaacacc uucuucaagc cccccugcgu gagcguguac      480

agaugcggcg gcugcugcaa cagcgagggc cugcagugca ugaacaccag caccagcuac      540

cugagcaaga cccuguucga gaucaccgug ccccugagcc agggccccaa gcccgugacc      600

aucagcuucg ccaaccacac cagcugcaga ugcaugagca agcuggacgu guacagacag      660

gugcacagca ucaucagaag aagccugccc gccacccugc cccagugcca ggccgccaac      720

aagaccugcc ccaccaacua cauguggaac aaccacaucu gcagaugccu ggcccaggag      780

gacuucaugu ucagcagcga cgccggcgac gacagcaccg acggcuucca cgacaucugc      840

ggccccaaca aggagcugga cgaggagacc ugccagugcg ugugcagagc cggccugaga      900

cccgccagcu gcggccccca caaggagcug gacagaaaca gcugccagug cgugugcaag      960

aacaagcugu uccccagcca gugcggcgcc aacagagagu ucgacgagaa caccugccag     1020

ugcgugugca agagaaccug ccccagaaac cagccccuga accccggcaa gugcgccugc     1080

gagugcaccg agagccccca gaagugccug cugaagggca agaaguucca ccaccagacc     1140

ugcagcugcu acagaagacc cugcaccaac agacagaagg ccugcgagcc cggcuucagc     1200

uacagcgagg aggugugcag augcgugccc agcuacugga agagacccca gaugagcuga     1260


<210>  598
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  598
auguacagag aguggguggu ggugaacgug uucaugaugc uguacgugca gcuggugcag       60

ggcagcagca acgagcacgg ccccgugaag agaagcagcc agagcacccu ggagagaagc      120

gagcagcaga ucagagccgc cagcagccug gaggagcugc ugagaaucac ccacagcgag      180

gacuggaagc uguggagaug cagacugaga cugaagagcu ucaccagcau ggacagcaga      240

agcgccagcc acagaagcac cagauucgcc gccaccuucu acgacaucga gacccugaag      300

gugaucgacg aggaguggca gagaacccag ugcagcccca gagagaccug cguggaggug      360

gccagcgagc ugggcaagag caccaacacc uucuucaagc cccccugcgu gaacguguuc      420

agaugcggcg gcugcugcaa cgaggagagc cugaucugca ugaacaccag caccagcuac      480

aucagcaagc agcuguucga gaucagcgug ccccugacca gcgugcccga gcuggugccc      540

gugaaggugg ccaaccacac cggcugcaag ugccugccca ccgcccccag acaccccuac      600

agcaucauca gaagaagcau ccagaucccc gaggaggaca gaugcagcca cagcaagaag      660

cugugcccca ucgacaugcu gugggacagc aacaagugca agugcgugcu gcaggaggag      720

aacccccugg ccggcaccga ggaccacagc caccugcagg agcccgcccu gugcggcccc      780

cacaugaugu ucgacgagga cagaugcgag ugcgugugca agacccccug ccccaaggac      840

cugauccagc accccaagaa cugcagcugc uucgagugca aggagagccu ggagaccugc      900

ugccagaagc acaagcuguu ccaccccgac accugcagcu gcgaggacag augccccuuc      960

cacaccagac ccugcgccag cggcaagacc gccugcgcca agcacugcag auuccccaag     1020

gagaagagag ccgcccaggg cccccacagc agaaagaacc ccuga                     1065


<210>  599
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  599
auggccguga uggcucccag aacccugguc cuccugcuua gcggcgcccu ggcgcucaca       60

cagacguggg cu                                                           72


<210>  600
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  600
auggacgcca ugaagagagg ccugugcugu gugcuccugc uuugcggggc ugucuucguu       60

agccccucc                                                               69


<210>  601
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  601
augggcgugc acgagugccc cgccuggcug uggcuccugc uuagccugcu cucccugccu       60

cuugggcugc cgguccucgg a                                                 81


<210>  602
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  602
augaaguggg ugaccuucau cagccugcuc uuucuguucu ccucugccua cagc             54


<210>  603
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from 
       Artificial____cleavage site-Furin

<400>  603
agacggcgca gaaagcgg                                                     18


<210>  604
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  604
auggacagcg augagaccgg cuucgaacac uccgggcugu gggugucugu ccucgccgga       60

cugcuucugg gcgcuugcca ggcccauccc aucccugaca gcuccccgcu ccugcaauuu      120

gggggacagg uuagacagcg guaccuuuau acagaugacg cgcagcaaac ggaggcucac      180

cuggaaauuc gcgaggaugg caccgugggc ggagccgccg accagucucc cgaaagccuc      240

cugcagcuga aggcucucaa accuggcgug auccagauuc ugggcgucaa gacauccaga      300

uuccuuuguc aacggcccga uggggcccug uacggaucuc uccauuuuga cccugaggcu      360

ugcagcuucc gcgagcugcu ucuggaagau ggcuauaacg uguaccaguc cgaggcccac      420

gggcuccccc ugcaucugcc uggaaauaaa agcccgcaca gagaccccgc gccucggggc      480

cccgcccgcu uucucccucu gcccgggcuu ccgccugcuc ugcccgaacc ucccggaauc      540

cucgcucccc agccuccgga uguugggucu uccgaccccc ugagcauggu gggcccuucu      600

caggggagau cccccagcua ugccucuuga                                       630


<210>  605
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  605
augcacagcu uucccccucu gcuccugcuu cuguucuggg gcguggucuc ccauucuuuc       60

ccggccaccc ucgagacaca ggaacaagac guugaucugg ugcagaagua ccuugagaaa      120

uauuacaacc ugaagaauga cgggagacag guggaaaaac ggcgcaacag cggacccguc      180

guggagaagc ucaaacagau gcaagaauuu uucggccuga agguuacggg gaagccugau      240

gcugagaccc ugaaagugau gaagcagccc agaugcggag ucccugacgu ggcccaguuu      300

guucucacag agggcaaucc ccggugggaa cagacccacc ugacauaucg caucgagaac      360

uacaccccug aucuuccgag agcggacgug gaucaugcua uugaaaaagc cuuccaacug      420

ugguccaaug ucacaccccu caccuuuacg aaggugucug aggggcaggc cgacaucaug      480

auuagcuucg ugcggggaga ucaccgcgac aacuccccuu uugauggccc cggcgggaau      540

cuggcucaug ccuuccagcc uggacccggc aucgggggag acgcucacuu ugaugaggac      600

gaaagaugga ccaacaauuu ccgggaguau aaccuucacc gcgucgccgc gcaugaacug      660

ggccacucuc ucgggcugag ccauuccaca gacauuggag cccugaugua cccgagcuau      720

accuuuucug gcgauguuca gcucgcucaa gacgauaucg acggcaucca ggccauuuac      780

gggagauccc agaauccugu gcaacccauc ggaccucaga cacccaaggc uugugauagc      840

aaacugaccu ucgacgccau uacgacaauc cggggcgagg ugauguucuu uaaggaucgc      900

uucuacauga gaaccaaccc cuuuuauccu gaagucgagc uuaauuucau uucuguguuu      960

uggccgcagc ugcccaacgg gcucgaggcg gccuacgagu ucgcugaccg ggaugaaguu     1020

cgcuuuuuca aaggaaauaa guauugggcc gugcagggcc aaaacguccu gcacggguac     1080

ccuaaagaca ucuauuccag cuuuggauuc cccagaacag ugaagcacau ugaugcugcc     1140

cuuucugaag agaacaccgg caaaaccuac uuuuucguug ccaauaagua uuggcgguac     1200

gacgaauaca aaagauccau ggacccuggc uaucccaaga ugaucgcuca ugauuuuccg     1260

gggaucggac acaaggugga cgcggucuuc augaaagaug gcuucuuuua cuucuuucau     1320

gggacacgcc aguauaaguu cgacccuaaa acgaagcgga uucugacccu ccagaaagcc     1380

aacagcuggu uuaauugcag aaagaacuga                                      1410


<210>  606
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  606
augcacagcu uucccccucu gcuccugcuu cuguucuggg gcguggucuc ccauucuuuc       60

guucucaccg aggggaaccc gagaugggaa cagacacacc ugacguaccg gauugagaau      120

uauacccccg accuuccucg cgccgaugug gaccaugcua uugaaaaggc cuuucaacug      180

uggagcaacg ugacaccccu caccuucaca aaagucuccg agggacaggc ggauaucaug      240

auuucuuuug ugagaggcga ccaccgggau aauagcccuu ucgacgggcc cggaggcaac      300

cuggcucaug ccuuucagcc ugggccggga aucggcggcg augcccacuu cgacgaagau      360

gagcgcugga ccaauaacuu uagagaguac aaucugcacc ggguugcugc ccaugaacuc      420

gggcacuccc ugggacuuuc ucauagcaca gacauuggcg cucugaugua ucccuccuac      480

accuucagcg gggaugugca gcucgcccaa gacgauaucg acggaaucca ggcgauuuau      540

ggccgcucuc agaacccugu ccagcccauc gggccucaaa cgcccaaggc cugcgacucc      600

aaacugaccu uugaugcuau uacaaccauc agaggagagg ugauguucuu uaaggaccgg      660

uucuacaugc gcacaaaucc guucuauccu gaaguugagc uuaacuuuau uagcguguuc      720

uggccccagc ugccuaaugg ccucgaggcc gcuuacgaau uugccgauag agacgagguc      780

cgguucuuua aaggcaacaa guacugggcg gugcaggggc agaaugugcu gcacggauau      840

cccaaggaua ucuacucuuc cuucggcuuu ccccgcaccg ucaaacacau ugacgccgcu      900

cugagcgaag agaacacggg gaagacauau uucuuuguug ccaauaaaua cuggagauau      960

gaugaauaca agcggucuau ggacccugga uauccgaaaa ugaucgcuca ugauuucccc     1020

ggcaucgggc acaaggugga cgccguguuu augaaggaug gauucuuuua cuucuuccau     1080

ggcacccgcc aauacaaauu ugacccuaag acaaaaagaa uccucacccu gcagaaggcc     1140

aacuccuggu ucaacugucg gaaaaauuga                                      1170


<210>  607
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  607
augaagaaaa acauccugaa gauucucaug gacagcuacu ccaaagaguc uaagauccag       60

accgugagac gggucacaag cguuucccug cuugccgugu aucugacgau gaauaccucu      120

agccucgugc uggcuaaacc cauugaaaac acaaaugaua ccuccaucaa gaacgucgag      180

aaacuucgca augccccuaa cgaagaaaau ucuaaaaagg uggaagacag caaaaacgau      240

aagguugagc acgugaaaaa uauugaggaa gcgaaggucg agcaaguggc uccggaaguu      300

aaguccaaaa gcacacugag aucugccucc aucgccaaca ccaauagcga gaaguacgac      360

uucgaguauc ucaacggccu gucuuacaca gaacugacca aucucaucaa aaacauuaag      420

uggaaucaga ucaacgggcu guuuaacuau uccacgggaa gccagaaauu cuuuggcgau      480

aagaaucggg ugcaggcuau uaucaacgcc cuucaagagu cugggcgcac cuacacagcu      540

aaugacauga aaggaauuga aaccuucaca gagguccuga gagccggcuu uuaucucggg      600

uacuacaacg auggacuguc cuaucuuaau gaccggaacu uccaggauaa gugcaucccc      660

gcgaugauug ccauccagaa gaauccuaac uuuaaacugg gcaccgcugu gcaggacgaa      720

gugaucacga gccucggcaa gcugauuggg aaugccuccg cuaacgccga ggucguuaau      780

aacugugugc ccgugcugaa acaauuccgc gagaaucuca accaguacgc gccugauuau      840

gucaagggaa cagccgugaa ugaacugauc aaaggcauug aguuugacuu cucuggggcu      900

gccuacgaaa aggauguuaa gaccaugccc ugguauggaa aaaucgaccc uuuuauuaac      960

gagcuuaagg cucugggccu cuacgggaac aucacaagcg ccaccgaaug ggccuccgac     1020

gugggaaucu auuaccugag caaauucggc cuuuacucua ccaauagaaa cgauauuguc     1080

cagucccugg agaaggcugu ggacauguau aaauacggca agaucgcguu uguugccaug     1140

gagcggauua caugggauua ugacgggauc ggaagcaaug gcaagaaagu ggaucaugac     1200

aaguuccucg augacgcuga aaaacacuac cugccgaaga cguauaccuu cgauaacggg     1260

acauuuauua uccgcgccgg agacaaaguc ucugaggaaa agaucaagag acuguacugg     1320

gccagccggg aggugaaauc ccaguuccau cgcgucgugg gcaaugauaa ggcucucgaa     1380

guugggaacg ccgacgacgu gcugaccaug aaaauuuuua auucucccga ggaguauaag     1440

uucaacacaa auaucaacgg agucagcacc gauaauggcg gccuuuacau ugaaccuaga     1500

gggacguuuu acacauauga gcggacaccc caacagucca ucuucagccu ggaggagcuc     1560

uuucgccacg aguacaccca uuaucugcag gcgagauacc uuguggacgg acuguggggc     1620

caagggccuu ucuaugagaa aaaccggcuc accugguuug augaaggaac cgcugaguuc     1680

uuugccggcu cuacaagaac guccgggguu cugccccgca agagcauucu gggcuaccuc     1740

gccaaagaca agguggauca ccgguauucu cugaagaaaa cccuuaauuc cggauacgac     1800

gauagcgacu ggauguucua caacuauggc uuugcugucg cccacuaccu guaugaaaag     1860

gauaugccga cauucaucaa aaugaauaag gcuauucuca acaccgacgu gaaauccuac     1920

gaugaaauca ucaagaagcu gucugacgau gccaacaaaa auacagagua ucagaaccau     1980

auucaggagc uggcggacaa guaccagggg gccggaaucc cucuugugag cgacgauuau     2040

cucaaagacc acggcuacaa gaaggcuucc gaaguuuacu cugagauuag caaggccgcu     2100

ucccugacca auacgagcgu caccgccgaa aagucucaau auuucaacac auuuacccug     2160

agagggacau acaccggaga gacguccaaa ggcgaguuca aggauuggga cgaaaugagc     2220

aaaaagcucg augggacacu ggagucucuu gcgaaaaauu ccuggagcgg cuauaagacc     2280

cugacagccu acuuuaccaa cuaucgcgug accucugaca auaaggugca guacgauguc     2340

guguuccaug gaguucucac agacaacgcu gauaucagca auaacaaagc ccccauugcu     2400

aaggugacgg gcccuuccac cggggccguc ggacggaaua ucgaauuuag cggcaaagac     2460

ucuaaggaug aggacgggaa aaucgugucc uaugauuggg acuucggaga cggcgccaca     2520

agcagaggga agaacuccgu ucacgcuuac aaaaaggcgg gcaccuacaa ugugacacug     2580

aaggucaccg augacaaagg agccacggcu acagaaucuu uuaccauuga gaucaagaac     2640

gaagauacca caacccccau uacaaaagag auggagccca augacgauau caaggaagcc     2700

aacggcccua uuguggaggg gguuacggug aaaggagacc ugaacggcag cgaugacgcc     2760

gauaccuucu auuuugacgu caaggaagau ggggacguga caaucgagcu uccguacucc     2820

ggaucuagca auuucaccug gcucguguau aaggagggcg acgaucagaa ccacaucgcu     2880

uccgggauug acaaaaauaa cucuaagguc ggcacauuua aaagcaccaa gggacgccau     2940

uacguuuuca ucuauaaaca cgauuccgcc agcaauauuu cuuacucccu gaacaucaag     3000

ggccugggga augaaaagcu caaagagaag gaaaacaaug acagcucuga uaaagcgacg     3060

gugauuccca acuuuaauac cacaaugcag ggaucccugc uuggcgacga uagccgggac     3120

uauuacucuu ucgaggugaa ggaagagggg gaggucaaca ucgaacugga uaaaaaggac     3180

gaguucggag ugaccuggac acuccauccu gaauccaaua ucaacgauag aauuaccuac     3240

ggccaaguug acggcaauaa ggugagcaac aaagucaagc ugcgccccgg gaaauauuac     3300

cugcuugugu auaaguacuc cggaagcggc aauuaugagc uccggguuaa caaauga        3357


<210>  608
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  608
augaaguggg ugaccuucau cagccugcuc uuucuguucu ccucugccua cagcauugcu       60

aacacaaauu ccgagaaaua ugacuuugaa uaccuuaacg gccugucuua uacggagcuc      120

accaaucuga ucaagaacau uaaauggaau cagaucaacg ggcuuuucaa uuacagcaca      180

ggaucccaaa aguuuuucgg cgauaaaaac agaguccagg ccauuaucaa ugcgcugcag      240

gaaucugggc ggaccuauac agcuaacgac augaagggaa ucgagaccuu uacagaaguu      300

cuccgcgccg gcuucuaccu gggguauuac aaugauggac ugagcuaccu caacgacaga      360

aauuuucagg auaagugcau ucccgccaug aucgcuauuc agaaaaaccc uaauuucaag      420

cugggcaccg ccgugcaaga cgaggugauc acgucccuug gcaaacugau ugggaacgcu      480

agcgccaacg cggaggucgu gaauaacugu guuccggugc ucaagcaguu ucgggaaaau      540

cugaaccagu augcccccga uuacgucaaa ggaaccgcug ugaaugagcu uaucaagggc      600

auugaguucg acuuuucugg ggccgcuuau gaaaaggaug uuaaaacaau gccuugguac      660

ggaaagaucg accccuucau caacgagcug aaagcccucg gccuguaugg gaauauuacc      720

uccgcgacag aaugggccag cgauguggga aucuacuauc ugucuaaguu cggccucuac      780

uccaccaacc gcaaugacau uguccaaagc cuggagaaag cuguggauau guacaaguau      840

ggcaaaaucg ccuuuguggc uauggaaaga auuacguggg acuacgacgg gaucggaucu      900

aacggcaaga aggucgauca cgacaaauuc cuugaugacg ccgagaagca uuaucugccu      960

aaaacauaca ccuuugauaa ugggacauuc aucauucggg ccggagacaa gguuuccgaa     1020

gagaaaauca agcgccucua uugggcuagc agagagguga agucccaguu ucaccgggug     1080

gucggcaacg auaaagcgcu ggaagugggg aaugccgacg auguucuuac caugaagauu     1140

uucaacucuc ccgaggaaua caaauuuaau accaacauca acggagugag cacagacaau     1200

ggcggccugu auauugagcc ucgcgggacg uucuacaccu acgaaagaac accgcagcag     1260

uccaucuuua gccucgagga gcuguuccgg caugaauaua cccacuaccu gcaagcucgc     1320

uaucucgucg auggacugug gggccagggg cccuuuuacg agaagaacag acuuacaugg     1380

uucgacgaag gaaccgccga guuuuucgcc ggcucuacgc ggacauccgg ggugcugccu     1440

cgcaaaagca uccucggcua ucuggcuaag gacaagguug aucauagaua cucucuuaaa     1500

aagacccuga auagcggaua ugacgauucc gacuggaugu ucuacaacua cggcuuugcc     1560

guggcgcacu aucucuacga aaaagauaug cccaccuuca uuaagaugaa uaaagcuauc     1620

cugaacacag acgucaaguc uuaugaugag auuaucaaga aacugagcga cgaugccaau     1680

aagaacaccg aguaccagaa ucacauucaa gaacucgccg acaaauauca gggggcugga     1740

aucccucugg uguccgauga cuaccuuaag gaucauggcu auaaaaaggc cagcgagguc     1800

uacucugaaa uuuccaaagc ugccagccug acaaacacgu cugugaccgc ggagaagucc     1860

caguacuuua auacauucac ccuccggggg acauauaccg gagagacgag caagggcgaa     1920

uuuaaagacu gggacgagau guccaagaaa cuggauggga cccuggaauc ucuugccaag     1980

aacagcuggu ccggcuacaa aacacucacc gcuuauuuca caaauuacag aguuaccucu     2040

gacaacaagg ugcaguauga ugucguguuu cacggaguuc ugacggacaa ugccgauauc     2100

agcaacaaca aggcucccau cgccaaagug acaggcccgu ccaccggggc ggucggacgc     2160

aauauugagu ucagcggcaa ggacucuaaa gaugaagacg ggaagaucgu guccuacgau     2220

ugggacuuug gagauggcgc cacaagccgg gggaaaaacu cugugcaugc uuauaagaag     2280

gccggcaccu acaauguuac ccugaaaguc acagacgaua agggagcuac ggccaccgag     2340

uccuucacaa uugagaucaa aaacgaagac accacaaccc cuauuacgaa ggagauggaa     2400

cccaaugacg auaucaaaga ggccaacggc ccuaucgugg aaggggugac agucaaggga     2460

gaccucaaug gcagcgauga cgcugauacc uuuuacuucg acgugaagga ggauggggac     2520

guuaccauug agcugcccua uucuggaagc uccaacuuua cauggcuugu guacaaagaa     2580

ggcgaugacc aaaaucacau cgcgagcggg auugauaaga acaauucuaa agucggcacc     2640

uucaagucca caaaaggaag acacuaugug uucaucuaca agcaugacag cgccuccaac     2700

auuucuuaua gccugaauau caaaggccuc gggaacgaga agcugaagga aaaagagaau     2760

aacgacuccu cugauaaggc uacgguuauc cccaacuuua auaccacaau gcagggaagc     2820

cugcuuggcg acgauucccg cgacuacuau ucuuucgaag ugaaagagga gggggaaguc     2880

aacauugagc ucgauaagaa agacgaauuu ggagugaccu ggacacugca cccugagagc     2940

aauaucaacg aucggauuac cuacggccag guugacggca auaagguguc caacaagguc     3000

aaacugagac cggggaagua cuaucuccug guguacaaau auagcggauc uggcaauuac     3060

gagcuucgcg ugaacaagug a                                               3081


<210>  609
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  609
augaaguggg ugaccuucau cagccugcuc uuucuguucu ccucugccua cagcaugaaa       60

aagaacauuc uuaaaauccu gauggacucc uauucuaagg agagcaaaau ucagacaguc      120

agacggguua cguccguguc ucuccuggcu guguaccuua ccaugaauac aagcucccug      180

guccucgcca agcccaucga aaacaccaau gauacaagca uuaagaacgu ggagaaacug      240

cgcaaugcgc cuaacgaaga aaauucuaag aaaguugaag acuccaagaa cgauaaagug      300

gagcacguca agaauaucga ggaagcuaag guggagcaag uugccccgga agugaaaagc      360

aagucuaccc ugagauccgc cagccggcgc agacggaaac gcaucgcuaa cacaaauucu      420

gagaaguaug acuuugagua ccucaacggc cuguccuaua ccgaacuuac gaaucugauu      480

aaaaacauca aguggaauca gauuaacgga cucuucaacu acagcaccgg aucccagaaa      540

uuuuucggcg auaagaauag aguccaggcc aucauuaacg cucugcaaga gucugggcgg      600

acauauaccg ccaaugacau gaagggaauc gaaacauuua ccgaggugcu ucgcgcgggc      660

uucuaccugg gguacuauaa cgauggacuc agcuaccuga augacagaaa cuuucaggau      720

aaaugcauuc ccgccaugau cgcuauccag aagaauccua acuucaaacu gggcacggcc      780

gugcaggacg aagucauuac aucccucggc aagcugaucg ggaaugcuag cgccaacgcg      840

gagguuguga auaacugugu gcccguccuu aaacaauuuc gggagaaucu gaaccaguau      900

gccccugauu acgugaaggg aaccgcuguu aaugaacuca uuaagggcau cgaguucgac      960

uuuucugggg ccgcuuauga aaaagaugug aagacaaugc ccugguacgg aaaaauugac     1020

ccuuucauca acgagcugaa ggcccuuggc cuguauggga acaucaccuc cgccaccgaa     1080

ugggcuagcg acgucggaau uuacuaccuc ucuaaauucg gccuguauag cacaaaucgc     1140

aacgauaucg ugcagucccu ggagaaggcg guugacaugu acaaguaugg caaaauugcc     1200

uuuguggcua uggagagaau cacgugggau uacgacggga uuggaucuaa uggcaagaaa     1260

gucgaucaug acaaguuccu cgaugacgcc gaaaaacacu aucugccgaa gaccuacaca     1320

uuugauaacg ggaccuucau cauccgggcc ggagacaagg ugagcgagga aaagauuaag     1380

cgccuuuauu gggcuuccag agaggucaaa agccaguuuc aucggguggu uggcaaugau     1440

aaggcccugg aaguggggaa cgcggacgac guccucacaa ugaaaaucuu caauucuccc     1500

gaggaguaca aguuuaacac caauauuaac ggagugucca cggauaaugg cggccuguac     1560

aucgaaccua gagggacauu cuauaccuac gagcgcacac cccaacagag cauuuuuagc     1620

cuugaggagc uguuccggca cgaguauacc cauuaccucc aggcuagaua ucugguugac     1680

ggacuguggg gccaagggcc uuuuuacgag aaaaaccgcc ucaccugguu cgaugaagga     1740

acagccgaau uuuucgccgg cuccacgcgg accagcgggg ugcugcccag aaaguccauc     1800

cuuggcuauc uggcuaagga caaagucgau caccgcuacu cucucaagaa aacacugaau     1860

agcggauacg acgauuccga cuggauguuc uauaacuacg gcuuugccgu ggcucacuau     1920

cuguacgaga aggauaugcc gaccuucauu aaaaugaaua aggccauccu uaacacagac     1980

gugaagucuu augaugaaau cauuaaaaag cucagcgacg augcgaacaa aaauaccgag     2040

uaccagaacc auauccagga gcuggccgac aaguaucagg gggcugggau uccucugguu     2100

uccgacgauu accucaaaga ccacggcuac aagaaggcca gcgaagucua uucugagauc     2160

uccaaagcug ccagccugac gaauaccucu gugacagcgg aaaaguccca auacuuuaac     2220

accuucacac uucgggggac cuauacggga gagacaagca aaggcgaauu uaaggauugg     2280

gacgagaugu cuaaaaagcu ggaugggacc cucgagagcc uggccaaaaa uuccuggagc     2340

ggcuacaaaa cacugaccgc uuauuucacc aacuacagag ugacaucuga caauaagguc     2400

caguaugaug ugguuuuuca uggagugcuu acggacaacg ccgauauuuc caauaacaaa     2460

gcucccaucg ccaaggucac cggcccuagc acaggggccg ugggacgcaa uaucgaguuc     2520

uccggcaaag acucuaagga ugaagacggg aaaauuguua gcuacgauug ggacuuugga     2580

gacggcgcua ccucccgggg gaagaacucu gugcacgcgu acaagaaagc cggcacauau     2640

aaugucaccc ucaaggugac ggaugacaaa ggagcuacag ccaccgaauc uuucaccauc     2700

gagauuaaga acgaagauac aaccacaccc aucacgaaag agauggagcc caaugacgau     2760

auuaaggaag ccaacggccc uaucguugag ggggugaccg ucaagggaga ccugaacggc     2820

uccgaugacg cugauacauu uuacuucgac gugaaagaag auggggacgu gaccaucgag     2880

cugccguauu cuggaagcuc caauuuuaca uggcucgucu acaaggaggg cgacgaucag     2940

aaccacauug ccagcgggau cgacaaaaau aacucuaagg uuggcaccuu caaauccacg     3000

aagggaagac auuauguguu cauuuacaag cacgauagcg cgucuaauau cuccuauagc     3060

cugaacauua aaggccuugg gaaugaaaag cugaaagaga aggaaaacaa ugacucuucc     3120

gauaaagcua ccgugauccc caacuuuaau acaaccaugc agggaagccu ccugggcgac     3180

gauucccgcg acuacuacag cuucgagguc aaggaagagg gggaggugaa caucgaacug     3240

gauaagaaag acgaguuugg aguuacaugg acccuucauc cugaaucuaa uauuaacgau     3300

cggaucacau auggccaagu ggacggcaau aaggucagca acaaagugaa gcucagaccc     3360

gggaaauacu aucugcuggu uuacaaguau uccggaucug gcaauuacga gcuccgggug     3420

aacaaguga                                                             3429


<210>  610
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  610
augaacuucc ugaagaucau ucucaauaga ggcaaaacca ugaagcggaa augccugagc       60

aagcgccuua ugcuggccau cacaauggcu acgauuuuua ccgugaacuc cacacucccc      120

aucuacgccg cggucgacaa aaauaacgcu accgccgccg uucagaauga gucuaagaga      180

uauacaguga gcuaccugaa gacccuuaac uauuacgauc ugguggaccu ccuggucaaa      240

acagaaauug agaaucugcc ugaucucuuc caauauuccu cugacgcuaa ggaauuuuac      300

gggaacaaaa cccggaugag cuucaucaug gaugagaucg gacgcagagc cccgcaguau      360

acggaaauug accacaaggg cauccccacc cugguggagg uugugcgggc uggguuuuac      420

cuuggauucc auaauaaaga gcugaacgaa auuaauaagc gcuccuuuaa ggagagaguc      480

aucccuucua uucucgccau ccagaaaaac cccaauuuca agcugggcac agaagugcag      540

gauaaaauug uuagcgcgac cgggcuucug gccggaaacg agacagcucc ucccgaggug      600

gucaauaacu uuaccccuau ccuccaagac uguaucaaga acauugaucg guacgcccug      660

gacgaucuga aauccaaggc ucucuucaau gugcuggccg cgccgacgua ugacaucaca      720

gaauaccuuc gcgccaccaa agagaagccc gaaaacacac cuugguaugg caagauugau      780

ggcuuuauca augagcugaa aaagcucgcu cuguacggga aaauuaacga caauaacagc      840

uggaucaucg acaauggaau uuaucacauc gcuccccuug gcaagcugca uucuaacaau      900

aaaauuggga ucgaaacccu caccgaggug augaaggucu acccuuaucu guccaugcag      960

caccuucaga gcgccgauca gauuaagaga cauuacgacu cuaaagaugc cgagggaaac     1020

aagauccccc ucgacaaauu caagaaagaa ggcaaggaga aguacugccc gaaaacauau     1080

acguuugaug acgggaaggu uaucauuaaa gccggagcuc ggguggaaga ggaaaaggug     1140

aaacgccugu acugggcguc caaggagguc aauagccaau ucuucagagu guauggcauc     1200

gauaagccuc uugaggaagg caaccccgac gauauucuga ccaugguuau cuacaauucu     1260

ccugaggaau auaaacucaa cuccgugcug uacggguaug acacaaauaa cggaggcaug     1320

uacauugagc ccgaagggac cuuuuucaca uacgagcggg aggcccagga aagcaccuau     1380

acgcuugagg aacuguuucg ccacgaguac acacacuauc uccagggaag auacgcuguc     1440

cccggccagu gggggcggac caagcuguau gauaacgaca gacugaccug guacgaggaa     1500

ggaggcgccg aacucuucgc cggcuccaca cgcaccucug ggauccugcc ucggaaaagc     1560

auugugucca auauccauaa cacaacgaga aauaaccgcu auaagcugag cgacaccguu     1620

cacucuaaau acggagcuuc cuuugaguuc uacaauuaug ccuguauguu uauggauuac     1680

auguauaaca aggacauggg cauccugaau aaacucaacg aucuggcgaa gaauaacgac     1740

guggaugggu acgacaauua uauucgggau cugagcucua acuacgcucu uaaugacaag     1800

uaucaagauc auaugcagga gagaaucgac aacuacgaaa aucucacagu cccguucgug     1860

gccgaugacu accugguccg ccacgccuau aaaaacccca acgagauuua cagcgagauc     1920

uccgaagugg cuaagcugaa agaugccaag ucugagguua aaaagagcca guauuuuucc     1980

accuucacac uccggggaag cuacaccggc ggggcuucua agggcaaacu ggaagaccaa     2040

aaggccauga auaaauuuau ugacgauucc cuuaagaaac uggacacgua uagcuggucu     2100

ggauacaaga cccucacagc guauuucacc aacuacaagg uggauuccag caauagaguc     2160

acauacgacg ugguuuuuca cggcuaucug ccuaacgagg gggauuccaa aaauucucug     2220

cccuacggaa agaucaacgg caccuauaaa gggacggaaa aggagaaaau caaguucagc     2280

uccgagggau cuuucgaccc ugauggcaag auugugagcu acgaauggga cuuuggggau     2340

ggcaauaaau ccaacgagga aaaucccgag cauagcuaug acaaggucgg aacauacacc     2400

gugaaacuua aggugacaga ugacaaaggc gaaucuuccg uuagcaccac cacagccgag     2460

aucaaggauc ucucugagaa caaacugccg gucauuuaua ugcacgugcc uaaguccggg     2520

gcucugaauc agaagguggu cuucuacgga aaaggcacgu acgaccccga cgggagcauc     2580

gccggauauc agugggauuu uggcgacggg ucugauuuca gcuccgaaca gaacccuagc     2640

cauguguaca ccaagaaagg cgaguauaca guuacccucc gcgugaugga cucuuccgga     2700

caaaugagcg aaaagacaau gaaaauuaag aucaccgauc ccgucuaccc uaucggcacg     2760

gagaaggagc ccaauaacuc caaagaaaca gcuucugggc cgauugugcc uggaaucccc     2820

guuagcggca ccauugagaa uaccuccgac caggauuauu uuuacuucga cgugaucaca     2880

cccggggaag ucaagauuga uaucaacaaa cugggauaug gcggggccac cugggugguu     2940

uacgacgaga acaauaacgc ggugucuuac gccacagaug acggccagaa ucuuagcgga     3000

aaguuuaaag cugacaagcc uggccgguau uacauccacc uguauauguu caacgggucc     3060

uacaugccgu auagaauuaa uaucgaagga ucugucggcc gcuga                     3105


<210>  611
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  611
augaagagaa aaugccugag caagcggcuc augcuggcca ucaccauggc uacaauuuuc       60

acggugaacu ccacccuucc caucuacgcc gcggucgaca aaaauaacgc uacagccgcc      120

guucagaaug agucuaagcg cuauaccgug agcuaccuga aaacacucaa cuauuacgau      180

cugguggacc uucuggucaa gaccgaaauu gagaaucucc cugaucuguu ucaauauucc      240

ucugacgcua aggaguucua cggcaacaaa acaagaauga gcuuuaucau ggaugaaauu      300

gggcggcgcg ccccgcagua uaccgaaauc gaccacaagg gaauccccac gcugguggag      360

guugugagag cuggcuucua ccucggguuu cauaauaaag agcugaacga aauuaauaag      420

cgguccuuca aagagcgcgu caucccuucu auucuugcca uccagaagaa ccccaauuuu      480

aagcugggaa ccgaagugca ggauaaaauu guuagcgcga caggccuccu ggccgggaac      540

gagaccgcuc cucccgaggu ggucaauaac uucacaccua uccuucaaga cuguauuaag      600

aauaucgaua gauacgcccu ggacgaucuc aaauccaagg cucuguuuaa cgugcuggcc      660

gcgccgaccu augacaucac ggaauaccuc cgggccacaa aagagaagcc cgaaaacacc      720

ccuugguaug gaaaaauuga uggcuucauc aaugagcuga agaaacuugc ucuguacggc      780

aagauuaacg acaauaacag cuggaucauu gacaauggga ucuaucacau cgcuccccuc      840

ggaaagcugc auucuaacaa uaaaauuggc aucgaaacac uuaccgaggu gaugaagguc      900

uacccuuauc uguccaugca gcaccuccag agcgccgauc agauuaaacg ccauuacgac      960

ucuaaggaug ccgaggggaa caagaucccc cuggacaaau uuaagaaaga aggaaaggag     1020

aaauacugcc cgaagaccua uacauucgau gacggcaagg uuauuaucaa agccggggcu     1080

agaguggaag aggaaaaggu gaaacggcug uacugggcgu ccaaggaggu caauagccaa     1140

uuuuuccgcg uguauggaau cgauaaaccu cucgaggaag gcaaccccga cgauauucug     1200

acgaugguua ucuacaauuc uccugaggaa uauaaacuua acuccgugcu guacggcuau     1260

gacaccaaua acgggggaau guacauugag cccgaaggca cauucuuuac cuacgagaga     1320

gaggcccagg aaagcacaua uacccucgag gaacuguucc ggcacgagua cacgcacuau     1380

cuucaggggc gcuacgcugu ccccggacag uggggcagaa caaagcugua ugauaaugac     1440

cggcucaccu gguacgagga agggggagcc gagcuguuug ccggcuccac cagaacaucu     1500

ggcauccugc cucgcaagag cauugugucc aacauccaua acaccacacg gaauaacaga     1560

uauaagcuca gcgacacggu ucacucuaaa uacggggcuu ccuucgaauu uuacaauuau     1620

gccuguaugu ucauggauua cauguauaac aaggacaugg gcauucugaa uaaacuuaac     1680

gaucuggcga agaauaacga cguggaugga uacgacaauu auauccgcga ucucagcucu     1740

aacuacgcuc ugaaugacaa auaucaagau cauaugcagg agcggaucga caacuacgaa     1800

aaucugaccg ucccguuugu ggccgaugac uaccuuguca gacacgccua uaagaacccc     1860

aaugagauuu acagcgagau cuccgaagug gcuaagcuca aagaugccaa gucugagguu     1920

aaaaagagcc aguauuucuc cacauuuacc cugcgcggga gcuacacagg aggcgcuucu     1980

aaagggaagc uggaagacca aaaggccaug aacaaauuca uugacgauuc ccucaagaaa     2040

cuggacaccu auagcugguc uggcuacaag acgcuuaccg cguauuuuac aaacuacaaa     2100

guggauucca gcaaucgggu caccuacgac gugguuuucc acggauaucu gccuaacgag     2160

ggcgauucca aaaauucucu ccccuacggg aagaucaacg gaacauauaa gggcaccgaa     2220

aaggagaaaa uuaaguuuag cuccgagggg ucuuucgacc cugauggaaa aaucgugagc     2280

uacgaauggg acuucggcga ugggaauaag uccaacgagg aaaaucccga gcauagcuau     2340

gacaaggucg gcacguacac agugaaacug aaggugaccg augacaaagg agaaucuucc     2400

guuagcacaa ccaccgccga gaucaaggau cugucugaga acaaacuucc ggucauuuau     2460

augcacgugc cuaaguccgg cgcucucaau cagaaagugg ucuuuuacgg gaagggaaca     2520

uacgaccccg acggcagcau cgccggguau cagugggauu ucggagacgg cucugauuuu     2580

agcuccgaac agaacccuag ccauguguac acgaagaaag gggaguauac cguuacacug     2640

agagugaugg acucuuccgg ccaaaugagc gaaaagacca ugaaaauuaa gaucacagau     2700

cccgucuacc cuauuggaac cgagaaagag cccaauaacu ccaaggaaac ggcuucuggc     2760

ccgaucgugc cugggauccc cguuagcgga acaauugaga auaccuccga ccaggauuau     2820

uucuacuuug acgugaucac ccccggcgaa gucaagauug auaucaacaa acugggguau     2880

ggaggcgcca cauggguggu uuacgacgag aauaacaacg cggugucuua cgccaccgau     2940

gacgggcaga aucucagcgg caaguucaaa gcugacaagc cuggacgcua uuacauucac     3000

cuguauaugu uuaacggcuc cuacaugccg uaucggauca auaucgaagg gucugucgga     3060

agauga                                                                3066


<210>  612
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  612
augaaguggg ugaccuucau cagccugcuc uuucuguucu ccucugccua cagcguccag       60

aacgagucca aaagauauac aguuucuuac cuuaagacgc ugaauuauua cgaccucgug      120

gaucugcuug ugaaaaccga aauugagaac cugcccgacc ucuuucaaua uagcuccgau      180

gcuaaggagu ucuacggcaa uaaaacacgg augucuuuua ucauggacga aauugggcgc      240

agagccccuc aguauaccga aaucgaucac aagggcauuc cgacacuggu cgaggugguu      300

cgggcgggau ucuaccuggg guuucauaac aaggagcuca augaaaucaa caaacgcagc      360

uucaaggaga gagugauccc cuccauucug gcuauccaga aaaauccuaa cuuuaagcug      420

ggaaccgaag uccaggacaa aauugugagc gccacaggcc ugcucgccgg gaaugagacc      480

gcucccccug agguugugaa caauuucacg cccauccugc aagauugcau uaagaacauc      540

gaccgguacg cccuugauga ccugaagucu aaagcucucu uuaauguccu ggccgcgccu      600

accuaugaua uuacagaaua ccugcgcgcc accaaggaga aaccggaaaa cacacccugg      660

uauggaaaga ucgacggcuu caucaaugag cucaaaaagc uggcucuuua cggcaaaauu      720

aacgauaaca auuccuggau cauugacaac gggaucuauc acauugcccc ucugggaaag      780

cuccauagca auaacaagau cggcaucgaa acccugacgg aggugaugaa aguguacccc      840

uaucuuucua ugcagcaccu ucaguccgcu gaccagauua agagacauua cgauagcaaa      900

gacgccgagg ggaauaagau cccucucgau aaauuuaaga aggaaggaaa agagaaguac      960

ugucccaaaa cauauaccuu cgacgauggc aaggucauua ucaaagcggg ggcccggguu     1020

gaagaggaaa aggugaagcg ccuguacugg gcuucuaaag aggugaacuc ccaauucuuu     1080

agagucuaug gaauugacaa gccgcuggag gaaggcaauc cugaugacau ccucacaaug     1140

gugaucuaca acagccccga ggaauauaaa cuuaauuccg uucuuuacgg cuaugauacc     1200

aacaaugggg gaauguacau ugagccugaa ggcaccuucu uuacauacga gcgggaggcc     1260

caggaaucua cguauacccu ggaggaacuc uuccgccacg aguacacaca cuaucugcag     1320

gggagauacg cugugcccgg acaguggggc cggaccaagc uguaugacaa cgaucgccug     1380

acaugguacg aggaaggggg agccgagcuc uuugccggca gcaccagaac guccggcauc     1440

cugccccgga aaagcauugu cucuaauauc cauaacacaa ccagaaauaa ccgcuauaag     1500

cuguccgaca ccgugcacag caaguacggg gcuucuuucg aauuuuacaa cuaugcgugc     1560

auguucaugg acuacaugua uaauaaagau augggcauuc ucaacaagcu gaaugaccuu     1620

gccaaaaaca augauguuga cggauacgau aacuauaucc gggaccugag cuccaauuac     1680

gcucucaacg auaaguauca agaccauaug caggagagaa uugauaauua cgaaaaccug     1740

acagugccuu uugucgccga cgauuaccug gugcgccacg ccuauaaaaa uccgaacgag     1800

aucuacucug agaucagcga agucgcuaaa cuuaaggacg ccaaguccga ggugaagaaa     1860

agccaguauu ucucuaccuu uacacuccgg ggguccuaca cgggaggcgc gagcaagggg     1920

aaacuggaag aucaaaaggc uaugaauaaa uucauugacg acucucugaa gaagcucgau     1980

accuauuccu ggagcggcua caaaacacug accgccuauu uuacaaacua caagguugac     2040

uccucuaaua gagugaccua cgaugucgug uuccacggau aucuucccaa cgagggcgac     2100

agcaaaaacu cccugccuua cgggaagauc aauggaacgu auaaaggcac cgaaaaggag     2160

aagauuaaau ucucuagcga gggguccuuu gaucccgacg gaaagaucgu uagcuacgaa     2220

ugggauuucg gcgacgggaa caaaucuaau gaggaaaacc cugagcauuc cuaugauaag     2280

gugggcacau acaccgucaa acucaaggug acagacgaua agggagaaag cucugugucc     2340

accacgacag ccgagauuaa agaccugagc gagaauaagc ugcccguuau cuauaugcac     2400

gucccgaaau cuggcgcucu uaaccagaag gugguguuuu acgggaaagg aaccuacgau     2460

ccugacggca gcaucgccgg guaucagugg gacuucggag auggcuccga cuuuagcucu     2520

gaacagaauc ccucccaugu cuacacaaag aaaggggagu auaccgugac ccuccgcguu     2580

auggauagcu ccggccaaau gucugaaaag acaaugaaga uuaaaaucac ggacccugug     2640

uaccccauug gaaccgagaa ggagccuaac aauagcaaag aaacagcuuc cggccccauc     2700

gucccgggga uuccuguguc uggaaccauc gagaacacaa gcgaucagga cuauuucuac     2760

uuugauguua ucacccccgg cgaagugaag auugacauca auaaacuggg guauggaggc     2820

gccacguggg ucguguacga ugagaacaau aacgcgguuu ccuacgccac agacgauggg     2880

cagaaucugu cuggcaaguu caaggcugac aaacccggac gguauuacau ucaccucuau     2940

auguuuaacg gcagcuacau gccuuauaga aucaacauug aaggguccgu gggacgcuga     3000


<210>  613
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  613
augaaguggg ugaccuucau cagccugcuc uuucuguucu ccucugccua cagcaugaaa       60

agaaagugcc uuuccaaacg gcugaugcuc gcuauuacaa uggccacgau cuuuaccguc      120

aacucuacac ugcccauuua ugcggcuguu gacaagaaua acgccaccgc cgcucgcaga      180

cggcgcaaaa gagugcagaa ugagagcaag cgguacacag uguccuaucu uaagacccug      240

aacuacuaug aucucgucga ccugcuggug aaaacagaaa ucgagaaucu cccugaucug      300

uuccaauacu cuagcgacgc caaggaauuu uauggcaaca aaacccgcau guccuucauu      360

auggaugaga ucgggagacg ggcuccgcag uacacggaaa ucgaccacaa gggcauuccc      420

acccuuguug aggugguccg cgccggauuu uaccuggggu uccauaauaa agagcucaac      480

gaaaucaaua agagauccuu uaaggagcgg gugauuccuu cuauccuggc gauucagaaa      540

aaccccaauu ucaaacuugg aacagaaguu caggauaaga ucguguccgc caccggccug      600

cucgcuggga acgagacagc cccucccgag gucgugaaua acuuuacccc uauucugcaa      660

gacuguauca agaauaucga ucgcuaugcu cuggacgauc ucaaaagcaa ggcccuguuc      720

aacgugcuug cggccccgac guacgacauu acagaauauc ugagagcuac caaagagaag      780

cccgaaaaca caccuuggua cggaaagauc gauggcuuua uuaaugagcu caaaaagcug      840

gcccuuuaug gcaaaaucaa cgacaauaac ucuuggauua ucgacaaugg gaucuaccac      900

auugcucccc ugggaaagcu ccauuccaac aauaaaaucg gcauugaaac ccugaccgag      960

gucaugaagg uuuauccuua ccugagcaug cagcaccucc agucugccga ucagaucaag     1020

cggcauuacg acuccaaaga ugccgagggg aacaagauuc cccuggacaa auucaagaaa     1080

gaaggaaagg agaaguauug cccgaaaaca uacacguucg augacggcaa ggugaucauc     1140

aaagcugggg cgcgcgugga agaggaaaag gucaaaagac uuuauugggc cagcaaggag     1200

gugaauagcc aauuuuuccg gguuuacgga auugauaagc cucuggagga aggcaacccc     1260

gacgauaucc ucaccauggu gauuuauaau ucuccugagg aauacaaacu gaacagcguc     1320

cuuuauggcu acgacacaaa uaacggggga auguacaucg agcccgaagg caccuuuuuc     1380

acauaugaga gagaggcuca ggaauccacc uacacgcugg aggaacucuu ucgccacgag     1440

uauacacacu accugcaggg gcgguaugcc gugcccggac aguggggcag aaccaagcug     1500

uacgauaaug accgccucac cugguaugag gaagggggag ccgagcuguu cgcuggcagc     1560

acacggaccu cuggcauucu uccuagaaaa uccaucguua gcaacauuca uaacacaacg     1620

cgcaauaacc gguacaagcu gucugacacc gugcacagca aauacggggc cuccuuugag     1680

uucuauaauu acgcguguau guuuauggau uauauguaca acaaggacau gggaauccuc     1740

aauaaacuga acgaucuggc uaagaauaac gacgucgaug gcuaugacaa uuacaucaga     1800

gaucuuucua gcaacuaugc ccucaaugac aaguaccaag aucauaugca ggaacgcauu     1860

gacaacuacg aaaaucugac agugccguuc gucgccgaug acuaucuggu gcggcacgcu     1920

uacaaaaacc ccaaugagau cuauuccgag auuagcgaag uugccaagcu caaagaugcu     1980

aagucugagg ugaaaaaguc ccaguacuuu agcaccuuca cacugagagg gucuuauacc     2040

ggaggcgccu ccaaggggaa acuugaagac caaaaggcga ugaacaaauu uaucgacgau     2100

agccugaaga aacucgacac guacuccugg ucuggcuaua agacccugac agccuacuuc     2160

accaacuaca aggucgauag cuccaaucgc gugacauaug acguuguguu ccacggauac     2220

cugccuaacg agggcgauuc uaaaaauagc cuucccuaug ggaagauuaa cggaaccuac     2280

aaaggcacgg aaaaggagaa aaucaaguuu uccagcgagg ggucuuucga cccugaugga     2340

aagaucgucu ccuaugaaug ggacuuuggc gaugggaaua aaagcaacga ggaaaauccc     2400

gagcauucuu acgacaaggu gggcacauau accgugaaac ucaagguuac agaugacaaa     2460

ggagaaucca gcgucucuac caccacagcu gagauuaagg aucugagcga gaacaaacug     2520

ccggugaucu acaugcacgu gccuaagucc ggcgcccuca aucagaaggu cguguucuac     2580

gggaaaggaa cguaugaccc cgacggcagc auugcugggu accaguggga uuuuggagac     2640

ggcucugauu ucuccagcga acagaacccu ucccauguuu auaccaagaa aggggaguac     2700

acagugaccc ugcgggucau ggacucuagc ggccaaaugu ccgaaaagac aaugaaaauc     2760

aagauuaccg aucccgugua uccuaucgga acggagaagg agcccaauaa cucuaaagaa     2820

acagccagcg gcccgaucgu uccugggauu cccguguccg gaaccaucga gaauaccucu     2880

gaccaggauu acuuuuauuu cgacgucauu acacccggcg aagugaagau cgauauuaac     2940

aaacuugggu acggaggcgc gaccuggguu guguacgacg agaauaacaa cgccgucagc     3000

uaugcuacag augacgggca gaaucugucc ggcaaguuua aagccgacaa gccuggaaga     3060

uacuauaucc accucuacau guucaacggc agcuauaugc cguaccggau caauauugaa     3120

gggucugugg gacgcuga                                                   3138


<210>  614
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  614
augggcaccu ggauccuguu cgccugccuc cugggggcug ccuuugcgau gccccuuccu       60

ccgcaccccg gacauccugg cuacauuaac uucagcuaug aggugcugac accccucaag      120

ugguaccagu ccaucagacc ucccuauccu ucuuacgggu augaaccgau gggaggcugg      180

cugcaccauc aaauuauccc cguccuuagc cagcagcacc cucccacgca uacccugcag      240

ccucaccacc auauucccgu ugugccggcu caacagccug ugauccccca gcagccuaug      300

augcccgucc ccgggcaaca cuccaugaca ccuauccagc aucaccagcc gaaucugccc      360

ccucccgccc agcaaccuua ccagccccag ccggugcaac cucagcccca ccagccuaug      420

cagccccaac cucccguuca uccgaugcag ccucucccuc cccagccccc gcugcccccu      480

auguuuccca ugcagccucu gcccccuaug cuccccgacc uuacccugga ggccuggccg      540

ucuacagaua aaaccaagcg ggaagaggug gacuga                                576


<210>  615
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  615
augccccugc cuccgcaccc cggccauccu ggguacauca acuucagcua ugaggugcuc       60

accccucuga agugguacca guccauuaga ccucccuauc ccucuuacgg auaugaaccg      120

augggcgggu gguga                                                       135


<210>  616
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  616
augccccugc cuccgcaccc cggccauccu ggguacauca acuucagcua ugaggugcuc       60

acaccccuga agugguacca guccauuaga ccucccccua ugcuuccgga ccugacccuc      120

gaagccuggc ccucuacgga uaaaaccaag cgggaggaag ucgacuga                   168


<210>  617
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  617
auggccguga uggcucccag aacccugguc cuccugcuua gcggcgcccu ggcgcucaca       60

cagacguggg cuaugccucu gccgccccac ccugggcauc ccggauacau caacuucucc      120

uaugagguuc uuaccccucu gaagugguac caaucuauuc ggcccccuua uccgagcuac      180

ggcuaugaac ccaugggagg gugguga                                          207


<210>  618
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  618
auggccguga uggcucccag aacccugguc cuccugcuua gcggcgcccu ggcgcucaca       60

cagacguggg cuaugccucu gccgccccac ccugggcauc ccggauacau caacuucucc      120

uaugagguuc uuaccccucu gaagugguac caaucuauuc ggcccccucc gaugcucccc      180

gaccugacac uggaagccug gccuagcacc gauaaaacaa agcgcgagga aguggacuga      240


<210>  619
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  619
augggcaccu ggauccuguu cgccugccuc gugggggcug ccuuugcgau gccccugccu       60

ccgcaccccg gacauccugg cuacauuaac uucagcuaug agguccuuac accccugaag      120

ugguaccagu ccaugaucag accucccuau ucuagcuacg gguaugaacc uaugggaggc      180

uggcuccacc aucaaauuau cccgguugug ucccagcagc acccccugac gcauacccuu      240

cagucucacc accauauucc uguggucccc gcucaacagc cucgggugcg ccagcaggcc      300

cugaugcccg uuccggggca acagagcaug acaccuaccc agcaccauca gcccaaucuc      360

ccucugcccg cccaacagcc cuuucagccu caaccggugc agccccagcc ucaccagccc      420

augcaaccuc agcccccggu ccagccuaug cagccccugc ucccucaacc cccucugccc      480

ccgauguucc cucuuagacc ccugcccccu auccucccgg accugcaccu ugaggcuugg      540

cccgccacag auaaaaccaa gcaggaagag guggacuga                             579


<210>  620
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  620
augccccugc cuccgcaccc cggccauccu ggguacauca acuucagcua ugaggugcuc       60

accccucuga agugguacca guccaugauu agaccucccu auucuagcua cggauaugaa      120

cccaugggcg ggugguga                                                    138


<210>  621
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  621
augccccugc cuccgcaccc cggccauccu ggguacauca acuucagcua ugaggugcuc       60

acaccccuga agugguacca guccaugauu agaccucccc cuauccuucc ggaccugcac      120

cucgaagccu ggcccgcuac cgauaaaacg aagcaagagg aagucgacug a               171


<210>  622
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  622
auggccguga uggcucccag aacccugguc cuccugcuua gcggcgcccu ggcgcucaca       60

cagacguggg cuaugccucu gccgccccac ccugggcauc ccggauacau caacuucucc      120

uaugagguuc uuaccccucu gaagugguac caaucuauga uucggccccc uuauagcucc      180

uacggcuaug aaccgauggg agggugguga                                       210


<210>  623
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  623
auggccguga uggcucccag aacccugguc cuccugcuua gcggcgcccu ggcgcucaca       60

cagacguggg cuaugccucu gccgccccac ccugggcauc ccggauacau caacuucucc      120

uaugagguuc uuaccccucu gaagugguac caaucuauga uucggccccc uccgauccuc      180

cccgaccugc accuggaagc cuggccugcc acagauaaaa ccaagcagga ggaaguggac      240

uga                                                                    243


<210>  624
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  624
augggcaccu ggauccuguu cgccugccuc cugggggcug ccuuuagcau gccccuuccu       60

ccgcaccccg gacauccugg cuacauuaac uucuccuaug aggugcugac accccucaag      120

ugguaccaga auaugaucag acacccuuau acgucuuacg gguaugaacc caugggaggc      180

uggcugcauc accaaauuau cccugucguu agccagcaga ccccgcaguc ccaugcgcuu      240

caaccccacc accauauucc uauggugccc gcucagcagc cugggauccc ccagcaaccg      300

augaugccuc ugcccggaca gcacucuaug acaccuaccc agcaucacca gcccaaccuc      360

ccccugccug cccaacagcc guuucagccc caaccugugc agccccagcc ucaccagccc      420

cugcaaccgc agagcccuau gcaucccauc cagccucucc ugccccagcc uccccuuccg      480

ccuauguucu ccaugcaauc ucugcucccc gaccugcccc uugaggccug gccugcuaca      540

gauaaaacca agcgggaaga ggucgacuga                                       570


<210>  625
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  625
augccccugc cuccgcaccc cggccauccu ggguacauca acuucagcua ugaggugcuc       60

acaccccuga agugguacca gaauaugauu agacacccuu auaccuccua cggauaugaa      120

cccaugggcg ggugguga                                                    138


<210>  626
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  626
augccccugc cuccgcaccc cggccauccu ggguacauca acuucagcua ugaggugcuc       60

acaccccuga agugguacca gaauaugauu agacacccuu cccuucugcc cgaccucccu      120

cuggaagccu ggccggcuac cgauaaaacg aagcgggagg aagucgacug a               171


<210>  627
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  627
auggccguga uggcucccag aacccugguc cuccugcuua gcggcgcccu ggcgcucaca       60

cagacguggg cuaugccucu gccgccccac ccugggcauc ccggauacau caacuucucc      120

uaugagguuc uuaccccucu gaagugguac caaaauauga uucggcaccc cuauacaucu      180

uacggcuaug aaccuauggg agggugguga                                       210


<210>  628
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  628
auggccguga uggcucccag aacccugguc cuccugcuua gcggcgcccu ggcgcucaca       60

cagacguggg cuaugccucu gccgccccac ccugggcauc ccggauacau caacuucucc      120

uaugagguuc uuaccccucu gaagugguac caaaauauga uucggcaccc cucucuccug      180

ccugaccugc cgcucgaagc cuggcccgcc acagauaaaa ccaagcgcga ggaaguggac      240

uga                                                                    243


<210>  629
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  629
augggcaccu ggauccuguu cgccugccuc cugggggcug ccuuuagcau gccccuuccu       60

ccgcaccccg gacauccugg cuacauuaac uucuccuaua ucagacaccc cuacacaucu      120

uauggguacg agccuauggg aggcuggcug caucaccaga uuauccccgu ggucagccaa      180

cagacgccuc agucccaugc gcuccagccg caccaccaua uucccauggu uccugcucaa      240

cagcccggga ucccucagca gcccaugaug ccgcugccug gacaacacuc uaugaccccc      300

acacagcauc accagccuaa ucuuccccug cccgcccagc aaccuuuuca gccgcagccc      360

gugcaaccuc agccccacca gccucuccag ccccaaagcc cgaugcaucc uauccagccc      420

cugcugccuc agcccccucu gcccccgaug uucuccaugc agucucuccu uccugaccug      480

ccccucgaag ccuggcccgc uaccgauaag acaaaacggg aggaagugga cuga            534


<210>  630
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  630
augggcaccu ggaucuucuu ugccugccug cucggggcua gccuggccau gccccuuccu       60

ccgcaccccg gacauccugg cuacauuaac uucuccuaug aggugcugac accccucaag      120

ugguaccaga auaugaucag acacccuuau acgucuuacg gguaugaacc caugggaggc      180

uggcugcauc accaaauuau cccugucguu agccagcaga ccccgcaguc ccaugcgcuu      240

caaccccacc accauauucc uauggugccc gcucagcagc cugggauccc ccagcaaccg      300

augaugccuc ugcccggaca gcacucuaug acaccuaccc agcaucacca gcccaaccuc      360

ccccugccug cccaacagcc guuucagccc caaccugugc agccccagcc ucaccagccc      420

cugcaaccgc agagcccuau gcaucccauc cagccucucc ugccccagcc uccccuuccg      480

ccuauguucu ccaugcaauc ucugcucccc gaccugcccc uugaggccug gccugcuaca      540

gauaaaacca agcgggaaga ggucgacuga                                       570


<210>  631
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  631
augggcaccu ggauccuguu cgccugccuc cugggggcug ccuuuagcau gccccuuccu       60

ccgcaccccg gacauccugg cuacauuaac uucuccuaug aggugcugac accccucaag      120

ugguaccaga auaugaucag acacccuucu cugcuucccg accugccucu cgaagcgugg      180

ccggcuacgg auaaaaccaa gcgggaggaa gucgacuga                             219


<210>  632
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  632
augggcaccu ggauccuguu cgccugccuc cugggggcug ccuuuagcau gccccuuccu       60

ccgcaccccg gacauccugg cuacauuaac uucuccuaug aggaccugua ccucgaagcg      120

aucagaauug aucggacagc uuuugugcug acgccccuua agugguauca gaauaugauc      180

cgccacccuu acaccucuua uggguacgag cccaugggag gcuggcugca ucaccaaauu      240

aucccugucg uuagccagca gacaccgcag ucccaugccc uccaacccca ccaccauauc      300

ccuauggugc ccgcccagca gccugggauu ccccagcaac cgaugaugcc ucugcccgga      360

cagcacucua ugaccccuac acagcaucac cagcccaacc ugccccuccc ugcucaacag      420

ccguuccagc cccaaccugu gcagccccag ccucaccagc cccugcaacc gcagagcccu      480

augcauccca uccagccucu ucugccccag ccuccccucc cgccuauguu uuccaugcaa      540

ucucugcuuc ccgaccugcc ccucgaagcc uggccugcua ccgauaaaac aaagagagag      600

gaagucgacu ga                                                          612


<210>  633
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  633
augggcaccu ggauccuguu cgccugccuc cugggggcug ccuuuagcau gccccuuccu       60

ccgcaccccg gacauccugg cuacauuaac uucuccuaug aggugcugac accccucaag      120

ugguaccaga auaugaucag acacccuacg ccccaaucuc augcgcugca gccucaccau      180

cacauuccga ugguccccgc ucagcagccu gggauccccc aacagccuau gaugccccuu      240

ccgggacagc acagcaugac cccuacacag caucaccaac ccaaccugcc ucuccccgcc      300

cagcagcccu uucagccuca accgguucag ccccagccuc aucaaccccu gcagccucag      360

ucccccaugc acccgauuca gccucugcuc ccccaaccuc cccugccucc cauguucucu      420

augcagagcc uucugccgga ccucccucug gaagccuggc ccgcuaccga uaaaacaaag      480

cgggaggaag uggacuga                                                    498


<210>  634
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  634
augccccugc cuccgcaccc cggccauccu ggguacauca acuucagcua ugaggugcuc       60

acaccccuga agugguacca gaauaugauu agacacccuu auaccuccua cggauaugaa      120

cccaugggcg gguggcuuca ucaccaaauc auuccugucg uuucucagca gacgccgcag      180

agccaugccc ugcaacccca ccaccauauc ccuauggugc ccgcucagca gccuggcauu      240

ccccagcaac cgaugaugcc ucuccccgga cagcacucca ugaccccuac acagcaucac      300

cagcccaacc ugccccuucc ugcccaacag ccguuucagc cccaaccugu gcagccccag      360

ccucaccagc cccugcaacc gcagucuccu augcauccca uccagccucu ccugccccag      420

ccuccccugc cgccuauguu cagcaugcaa ucccuccugc ccgaccuucc ccuggaggcg      480

uggccugcua ccgauaaaac aaagcgggaa gaggucgacu ga                         522


<210>  635
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  635
augcccggcg uggccagacu gccucuccug cuugggcugc uccugcuucc gcggcccgga       60

cgcccucugg accucgcuga uuacaccuau gaccuggccg aggaagauga cagcgagccc      120

cugaacuaca aggauccuug caaagcggcu gccuuccucg gcgacaucgc ccuggaugaa      180

gaggaccuua gagcuuuuca gguccaacag gccguugauc ugcggcgcca cacagcuaga      240

aaguccucua uuaaagccgc ggugcccggg aauacgagca ccccuuccug ucagucuaca      300

aacggacagc cgcaacgggg cgccugcggg cgcuggagag gacggagccg cuccagacgg      360

gcugccaccu cucgccccga aagagugugg ccugacggcg ucauccccuu cgugauuggc      420

gggaauuuua caggaagcca gcgggcuguu uuccgccagg ccaugagaca uugggagaag      480

cacaccugug ugacauuucu cgagcggacc gaugaagacu ccuauaucgu cuucacguac      540

agaccuugcg gcuguugcag cuaugugggg cgccggggag gcgggcccca ggcgauuucu      600

aucggaaaga acugugauaa guuuggcauc guugugcaug agcugggcca cgucgugggg      660

uucuggcaug aacacaccag accggaccgc gaccggcacg uguccauugu cagagagaau      720

auccaaccug gacaggagua caacuuucuu aagauggaac cccaggaggu ugaaagccug      780

ggcgagacau augauuucga cucuauuaug cauuacgccc gcaauaccuu uucccggggg      840

aucuuccucg auacaauugu gccuaaauac gaagugaacg gagucaagcc ucccaucggc      900

cagagaaccc gccugagcaa aggggacauu gcucaagccc ggaagcugua uaaaugcccc      960

gcuuguggag agacgcucca ggauucuaca ggcaauuuuu ccagcccgga guaccccaac     1020

ggcuauuccg cccacaugca uugcgugugg agaaucucug uuaccccugg ggaaaagauc     1080

auucugaauu ucacaagccu ugaccuguac cgcucccggc ucuguuggua ugauuacgug     1140

gaggucagag acggauucug gcggaaggcu ccccugcgcg gcagauuuug cgggagcaaa     1200

cuuccugaac ccaucguguc uaccgauucc cggcuguggg uugaguucag aagcucuagc     1260

aacugggugg gaaagggcuu uuucgccguc uaugaagcga uuugcggggg cgacgugaaa     1320

aaggauuacg gacacaucca guccccgaau uacccugacg acuaucgccc cucuaaaguc     1380

uguauuuggc ggauccaagu gagcgagggc uuucacguug ggcucaccuu ccaguccuuu     1440

gagaucgaaa gacaugauag cugcgccuac gacuaucugg aggugcgcga uggacacucu     1500

gaauccagca cacugauugg cagauacugu ggguaugaga agccugacga uaucaaaucu     1560

acguccagcc ggcucuggcu gaaguucguc uccgacggau cuauuaacaa ggcuggcuuu     1620

gccgugaauu ucuuuaaaga aguugaugag ugcagccgcc ccaacagagg gggcugugag     1680

cagcggugcc uuaacacccu gggauccuac aaguguucuu gcgacccugg cuaugaacuc     1740

gcccccgaua aacgcagaug ugaggcugcc ugcgggggau uccugacaaa acuuaauggc     1800

agcaucaccu ccccggggug gccuaaagaa uacccuccca acaagaauug uauuuggcag     1860

cugguggcgc ccacacaaua ccggaucagc cuccaguuug acuucuucga gaccgaggga     1920

aacgaugucu gcaaguauga cuuuguggaa gugcgcucug gccugacggc ugauuccaaa     1980

cugcauggga aguucugcgg cagcgagaaa ccggaaguua ucacaucuca guacaauaac     2040

augagagucg aguuuaaguc cgacaauacc gugagcaaaa agggauucaa ggcccacuuu     2100

uucucugaca aagaugaaug uagcaaggac aacggcgggu gccagcaaga uugugugaau     2160

accuuuggau ccuaugagug ccagugucgg agcggcuucg uccuccauga caacaaacac     2220

gauugcaagg aggccgggug ugaccacaaa gugacaucua ccuccggaac aauuacgagc     2280

cccaauuggc cugauaagua ccccuccaag aaagaaugca ccugggcuau cucuagcaca     2340

ccuggccauc gcguuaagcu gaccuuuaug gagauggaca uugaauccca gcccgagugu     2400

gccuaugauc accuugaagu guucgacggg agagaugcua aagccccugu ccugggccgg     2460

uuuugcggau cuaagaaacc cgagccggug cucgcgacag gcagcagaau guuccugcgc     2520

uuuuacuccg acaacucugu ucagcggaag ggguuccaag ccagccaugc uaccgagugu     2580

ggaggccagg ugagagccga ugucaaaacg aaggaccugu auucccacgc ucaguucggg     2640

gacaauaacu acccuggagg cguggauugc gaauggguua ucguggccga ggaaggcuac     2700

ggggucgagc uuguguuuca gaccuucgaa guggaggagg aaacagacug cggauaugau     2760

uacauggagc ucuuugacgg cuaugauagc accgcgcccc gccuggggcg guacugugga     2820

ucuggcccuc ccgaagaggu cuauuccgcc ggggacagcg uucuggugaa guuccacucu     2880

gaugacacaa uuaccaaaaa gggauuucau cucagauaca cguccacaaa auuccaagau     2940

acccugcaca gccgcaagug a                                               2961


<210>  636
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  636
augguggccg gcaccagaug ccugcucgcu cugcuucugc cccagguccu ccuuggggga       60

gccgcgggcc ugguuccuga gcuggggcgg cgcaaguucg cugccgccag cuccggaaga      120

ccgucuagcc aacccuccga cgaagugcuc ucugaguuug aacugcggcu gcucagcaug      180

uucggccuga aacagcgccc uacacccucc agagaugcug uggucccucc cuacaugcuu      240

gaccuguauc ggcgccacuc ugggcagccu ggaagcccgg cccccgauca uagacucgag      300

cgggcugccu cccgcgcgaa cacggugaga ucuuuucacc augaagaguc ucuggaggaa      360

cuuccugaga ccuccggcaa gacaacccgg cgcuucuuuu ucaaucugag cucuaucccc      420

acagaagagu uuauuaccuc cgccgagcuc cagguuuuca gagaacaaau gcaggacgcu      480

cugggcaaca auagcucuuu ucaccaucgg aucaacauuu acgagaucau uaaaccugcc      540

acagcuaauu ccaaguuccc cgugacccgc cugcucgaua cgagacuggu caaccagaau      600

gccagccggu gggaauccuu ugacgugacc ccggcgguua ugagauggac agcccagggg      660

cacgcuaacc acggauucgu ggucgaggug gcccaucuug aagagaaaca aggcgugucu      720

aagcgccacg uccggaucag cagaucccug caucaggaug agcacagcug gucucagauc      780

cgcccucucc ugguuaccuu ugggcacgac ggaaagggcc auccccuuca caaacgggaa      840

aagagacagg cuaaacauaa gcaacgcaaa cggcugaagu ccagcuguaa gagacacccu      900

cucuaugugg auuucucuga cguggggugg aaugauugga uugucgcccc ucccggauac      960

caugccuucu auugccacgg cgaguguccc uuuccgcugg cugaccaccu gaacagcaca     1020

aaucaugcga ucgugcagac ccucguuaac uccgugaaua gcaaaauucc caaggccugc     1080

ugugucccua cggaacugag cgcuaucucc augcuuuacc uggaugagaa cgaaaaagug     1140

guucucaaga auuaucagga cauggugguc gagggcugcg ggugucgcug a              1191


<210>  637
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  637
augauccccg gcaacagaau gcugauggug guccuccugu gccagguucu ucucggggga       60

gccagccacg cuucccugau uccugagacc ggcaagaaaa agguggccga aauccaaggg      120

caugcgggag gccggcgcuc ugggcagagc cacgagcugc uuagagacuu cgaagcuaca      180

cugcuccaga uguuuggacu gcggcgcaga ccgcagcccu ccaaaucugc cgugauuccu      240

gauuacaugc gggaccugua ucgccuccaa agcggcgagg aagaggagga acagauccau      300

uccacgggcc uggaguaccc cgaaagaccu gccucucggg cuaauaccgu ccgcagcuuc      360

caccaugagg agcaccuuga aaacauuccc gggacauccg agaauagcgc cuuuagauuc      420

cuguuuaacc ucucuuccau cccugaaaau gaggugauca gcucugcuga acugcggcuu      480

uuccgcgagc agguugauca gggaccggac ugggagagag gcuuucaccg gauuaacauc      540

uaugaaguga ugaagccccc ugccgagguc gugcccgggc aucugauuac ccgccuccug      600

gauacaagac ugguucacca uaaugugacc cggugggaaa cauucgacgu cuccccugcg      660

gugcucagau ggacccgcga gaaacaaccc aacuacggac uggccaucga agugacgcac      720

cuucaccaga cccggacaca ucagggccag cacgucagaa uuagccgcuc ucugccgcaa      780

ggguccggaa auugggcuca gcuccggccu cugcuuguua ccuuuggcca ugauggcaga      840

gggcacgccc ugacacgccg gagacgcgcu aagcggagcc ccaagcauca cucccagaga      900

gcccgcaaaa agaacaaaaa uugucggaga cacucucucu auguggacuu cagcgaugug      960

ggauggaacg acuggaucgu cgcgccuccc ggcuaccaag ccuuuuauug ccauggggau     1020

ugucccuucc cucuggcuga ccaccucaau uccaccaacc augccauugu gcagacgcug     1080

guuaauagcg ugaacucuuc caucccgaag gcuugcugug uccccacaga gcugagcgcc     1140

aucucuaugc uuuaccugga ugaguacgac aaagugguuc ucaagaacua ucaggaaaug     1200

guggucgagg gaugcggcug ucgguga                                         1227


<210>  638
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  638
augcccggcc uggggagacg ggcccagugg cucugcuggu gguggggacu gcuuuguagc       60

ugcuguggcc cuccgccccu gcgcccuccc cucccugcug ccgcggcugc cgccgcuggg      120

ggacaacugc uuggcgacgg gggauccccc ggcagaaccg agcagccucc gcccucuccu      180

cagagcuccu cuggcuuccu guaccggcgc cucaagacac aggagaaaag agaaaugcaa      240

aaggaaaucc ugagcgugcu ggggcucccc caccggccuc gcccccugca uggacuucag      300

cagccgcagc cucccgcccu gagacaacag gaggaacagc agcaacagca gcaacucccu      360

cggggcgagc ccccucccgg gcgccugaaa uccgcuccgc uuuuuaugcu ggaucucuau      420

aacgcccugu cugcggacaa ugaugaggac ggagccagcg aaggcgagag acagcagucc      480

uggccccacg aagcugccuc cucuucccag cggcgccaac cucccccugg ggcugcccau      540

ccccugaaca gaaagagccu ccuggcgccg ggaucuggcu ccggcggggc cagcccucuu      600

acgucugcuc aggauuccgc cuuccugaau gacgcugaua uggucaugag cuuuguuaac      660

cucguggagu acgacaaaga guucagcccc cggcagcgcc accauaagga auuuaaguuc      720

aaucugucuc agauuccuga gggagaagug gucaccgccg ccgaguuuag aaucuauaaa      780

gauugcguga ugggcagcuu caagaaccaa acauuucuua uuuccaucua ccagguucug      840

caggaacacc agcaccggga cagcgaucuc uuccugcugg acaccagagu ggucugggcu      900

ucugaggagg gguggcucga auuugauauu acagcgaccu ccaaucugug ggugguuaca      960

ccccaacaua acaugggacu ucagcugagc guggucaccc gcgacggcgu gcacgugcau     1020

ccucgggccg cugggcucgu cggaagagac ggccccuaug auaaacagcc guucaugguu     1080

gccuuuuuca aggugucuga ggugcacguc cgcacgaccc ggagcgccuc cucuagacgc     1140

cggcagcaaa gcagaaaucg cuccacacag agccaggacg uggcucgggu uucuuccgcc     1200

agcgauuaca acucuuccga acugaaaacc gcguguagaa agcacgagcu uuaugugagc     1260

uuccaagacc ugggcuggca ggauuggauc aucgcuccua agggguacgc cgccaauuac     1320

ugcgacggag aauguuccuu uccccucaac gcucauauga augccacaaa ccacgcuauu     1380

guccagaccc uggugcaucu gaugaauccc gaguauguuc cuaaaccgug cugugccccc     1440

acgaagcuca acgcgaucuc ugugcuguac uucgaugaca acagcaaugu cauucuuaaa     1500

aaguaucgca acaugguggu ccgggccugc ggcugucacu ga                        1542


<210>  639
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  639
augcacguga gaagccugcg ggccgcugcu ccccauuccu ucgucgcgcu cugggcuccu       60

cuguuucuuc ugcgcucugc ccucgccgac uucagccugg auaacgaggu ucacuccucu      120

uuuauccaua gacggcuucg cagccaggaa agacgggaga ugcaacgcga aauucugucc      180

auccucggcc ugccgcacag accccggccu caucugcagg ggaagcacaa uucugcuccc      240

auguucaugc ucgaccugua caacgccaug gcuguggagg aaggaggcgg gccuggaggc      300

cagggguuua gcuaucccua caaagccgug uucuccaccc agggaccucc gcuugcgagc      360

cugcaagauu cucacuuucu cacagacgcc gauaugguca uguccuucgu gaaucugguu      420

gagcaugaca aggaguuuuu ccacccccgc uaucaucaca gagaauuucg guucgaucuu      480

agcaaaauuc cugagggcga agcugugacg gccgcugagu uucgcaucua caaggacuau      540

auuagagagc gguucgauaa cgaaaccuuc cgcaucucug ucuaccaggu gcugcaggag      600

caccucggca gagaauccga ccuguuucug cucgauagcc ggacacugug ggccucugag      660

gaaggguggc uuguuuucga caucaccgcg acauccaauc auuggguggu caaccccaga      720

cacaaucugg gacuccagcu gagcguggag acccuugaug gccaauccau uaacccuaaa      780

cuggccgggc ucaucggacg ccauggcccc cagaauaagc agccguuuau gguggcuuuc      840

uuuaaggcca cagaggucca cuuccggucu auuagaagca ccggguccaa acagcgcagc      900

caaaaccggu cuaagacgcc uaaaaaucag gaagcucuga gaauggccaa cguugccgaa      960

aauuccagcu cugaccagcg ccaagccugc aagaaacaug agcuguaugu gagcuuucgg     1020

gaccucggau ggcaggauug gaucauugcg cccgagggcu acgccgcuua cuauugugaa     1080

ggcgagugcg ccuucccucu gaacuccuac augaaugcca ccaaccacgc uaucgugcag     1140

acacuugucc acuuuauuaa ccccgagacc gugcccaagc cuuguugcgc cccgacacag     1200

cugaaugcga ucucuguucu cuauuucgac gauagcucca acgugauccu gaagaaauac     1260

agaaauaugg ucgugcgcgc uugugggugc cauuga                               1296


<210>  640
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  640
augaaggcca gcgcugcccu gcucugccug cuucugaccg cggcugccuu cucuccccag       60

ggccucgccc aaccuguggg gaucaacaca uccacgaccu guugcuacag auuuauuaau      120

aaaaagaucc cgaaacagcg gcuggagagc uaucgcagaa caaccuccuc ucacuguccc      180

cgggaagcug ucauuuucaa gacaaaacuu gacaaggaga ucugcgccga uccuacccag      240

aaguggguuc aggacuuuau gaaacaucug gauaagaaaa cacaaacccc caagcucuga      300


<210>  641
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  641
augcugcuca cccugaucau ucuucugccc guggucagca aguucuccuu uguuucucuc       60

agcgccccuc agcacugguc cugcccggag ggcacacugg cugggaacgg aaauucuacg      120

ugugugggcc ccgccccuuu ccuuaucuuu agccauggga acuccauuuu cagaaucgac      180

accgaaggaa caaauuacga gcaacuggug gucgaugcgg gcgugucugu uauuauggac      240

uuucacuaua acgaaaaacg gaucuacugg guggaucucg agcgccagcu gcugcagaga      300

gucuuccuca augggagccg gcaggaacgc gugugcaaca ucgagaagaa uguuuccgga      360

auggcuauua acuggaucaa ugaggaagug auuuggagca accaacagga gggcaucauu      420

accgucacag acaugaaagg caauaacucu cauauccugc uuuccgcccu gaaguauccc      480

gccaaugugg cuguggaucc ugucgaaaga uuuauuuucu ggagcucuga gguugccggg      540

ucccucuacc gggcugaccu ggauggagug ggcgugaaag cccuucugga gaccagcgaa      600

aagaucacag cggucucucu cgacgugcug gauaagcgcc uguuuuggau ccaguauaac      660

agagaggggu ccaauagccu cauuuguucc ugcgacuacg auggaggcuc uguucacauc      720

agcaaacauc ccacccagca caaccuguuc gccauguccc uuuuugggga ccggauuuuc      780

uauagcacgu ggaagaugaa aaccaucugg auugcuaaca agcacacagg aaaagauaug      840

gugcgcauca aucugcauuc uuccuuuguc ccucucggcg aacugaaggu gguucacccg      900

cuugcccaac ccaaggcuga ggacgacacc ugggaaccug agcagaaacu guguaagcuc      960

agaaaaggca acugcagcuc uacagugugu gggcaggauc ugcagagcca ucugugcaug     1020

ugugccgagg gauacgcgcu cucccgggac cgcaaguacu gcgaagaugu caaugagugu     1080

gccuucugga accacggcug cacccugggg ugcaaaaaua cgcccggauc uuauuacugu     1140

acaugcccug ugggcuucgu ccuucugccc gacgggaaga gaugucacca acucgugagc     1200

ugcccgcgga acguuuccga auguagccau gauugcgugc ugaccucuga gggaccucuu     1260

uguuuuugcc ccgaaggcuc cguccuggag cgcgacggca aaacauguag cggguguucu     1320

uccccugaua auggaggcug cagccagcuc ugcgugcccc ugucccccgu uucuugggag     1380

ugcgacuguu ucccugggua ugaucugcag cucgacgaaa agagcugcgc ugccuccgga     1440

ccgcaacccu uucugcuuuu cgcuaacucu caggauauca gacacaugca uuuugacggc     1500

accgacuacg ggacccugcu cagccagcag augggcaugg uguaugcccu ggaucacgac     1560

ccugucgaga auaagauuua cuucgcccau acagcucuga aauggaucga acgggcgaac     1620

auggauggau cccaaagaga gcgccuuauu gaagagggcg uggacgugcc cgaggggcuc     1680

gccguugauu ggaucggacg gagauuuuau uggacggacc gcggcaagag ccugauuggg     1740

cggucugauc ugaauggaaa aagauccaag aucaucacca aagaaaacau uagccagccu     1800

cgcggcaucg cuguccaccc cauggccaag cggcuuuucu ggacagacac cgggauuaau     1860

ccgagaaucg agucuuccag ccugcagggc cuuggacgcc uggugauugc cucuagcgau     1920

cucaucuggc cuuccggcau uacaaucgac uuucugaccg auaagcugua cuggugugac     1980

gcuaaacaga gcgugaucga aauggccaac cuugaugggu cuaagcggag acgccucacg     2040

caaaaugacg ucggacaccc cuucgcggug gcuguuuuug aggacuacgu gugguucucc     2100

gauugggcca ugccuagcgu caugcgggug aacaaaagaa caggcaagga ccggguucgc     2160

cugcaggggu ccaugcugaa acccucuagc cucguggucg ugcauccucu ggccaagccc     2220

ggagcugauc cgugccuuua ucagaacggc gggugugagc acauuugcaa gaaaagacug     2280

ggcaccgccu gguguuccug ccgggaagga uuuaugaagg cuucugacgg caaaaccugu     2340

cucgcccugg augggcauca gcugcuugcg ggaggcgagg uugaccucaa gaaucaagug     2400

acaccucugg auauccugag caaaaccaga gucuccgaag acaacauuac agagucucag     2460

cacaugcucg uggccgaaau cauggugagc gaucaggacg auugcgcucc cgucgggugu     2520

uccauguacg cccgcugcau uagcgaggga gaggacgcua cgugccagug ucugaagggc     2580

uucgccgggg auggcaagcu cugcucugac aucgacgaau gugagauggg aguucccgug     2640

ugcccuccgg cguccagcaa auguaucaau accgaaggcg gguaugugug ccgguguucu     2700

gagggauacc aaggcgaugg gauucacugc cuggacaucg augaauguca gcucggagag     2760

cauuccugcg gcgagaacgc cagcuguaca aauaccgaag gcggguauac augcaugugc     2820

gcuggaagac ugucugagcc cggccugauu uguccugacu ccacgccccc uccccaccuu     2880

cgcgaagaug accaucacua cagcgucaga aacuccgaua gcgagugccc ucucucucau     2940

gacggguauu gucugcacga uggagugugc auguacaucg aagcccugga caaguacgcu     3000

uguaauugcg uugugggcua uauuggggag cggugucagu accgcgaucu caaauggugg     3060

gagcugagac acgccggaca uggccaacag cagaagguca ucgugguugc cgugugcguc     3120

gugguucuug ugaugcugcu ccugcugagc cuuuggggcg cucacuauua ccggacccag     3180

aaacugcucu ccaagaaccc caaaaauccg uaugaagagu cuagccgcga cgucagaucc     3240

cggcgcccug cggacaccga agaugggaug ucuagcuguc cccaaccuug guucguggug     3300

aucaaggagc aucaggaccu gaagaacgga ggccagcccg ucgccgggga ggauggacag     3360

gcugccgacg gcuccaugca accgacaucu uggagacagg aaccucagcu cugcgggaug     3420

ggaaccgagc agggcuguug gauucccguu agcuccgaua aaggcagcug cccucaagug     3480

auggaacggu cuuuucacau gcccuccuac gggacacaga cccuggaggg aggcguggaa     3540

aagccccaua gccuucuguc ugccaauccu cucuggcagc aacgcgcucu ggacccgccc     3600

caccagaugg agcugacgca guga                                            3624


<210>  642
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  642
augaccgccg gcagacggau ggagaugcug ugcgcugggc gcgugcccgc ccuccugcuu       60

ugucugggau uccaccuccu gcaggcgguc cuuagcacaa cgguuauccc uuccugcauu      120

ccgggcgaau cuagcgacaa cuguaccgcu cuggugcaaa cagaggauaa ucccagagug      180

gcccaggucu ccaucaccaa gugcucuagc gacaugaacg gguacugucu ccauggacag      240

ugcauuuauc ugguggauau gucccagaau uacugucggu gcgaaguugg cuauacaggg      300

gugcgcugug agcacuuuuu ccugaccguc caucaaccuc ucucuaaaga auacguggcc      360

cugacaguua uccuuauuau ccuguuucuc aucaccgugg ucggaagcac guauuacuuc      420

ugcagauggu aucggaaccg caaguccaaa gagcccaaga aagaguacga aagagugacc      480

agcggcgacc cugagcugcc ccagguguga                                       510


<210>  643
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  643
auggccgagg gcgaaaucac cacauucacg gcucugaccg agaaguuuaa ccugcccccu       60

gggaauuaca aaaagccgaa acuccuuuau ugcagcaacg gaggccacuu ccugcggauu      120

cuccccgacg ggacagugga uggaaccaga gaccgcuccg aucagcauau ccaacugcag      180

cuuucugccg aaagcgucgg cgagguuuac auuaagucca cagaaaccgg gcaguaucug      240

gcgauggaca cagauggacu ccuguacggc ucucagaccc cuaaugagga gugucuguuu      300

cucgaaagac uggaggaaaa ccacuauaau acguacauca gcaaaaagca ugcugagaag      360

aacugguucg ugggccuuaa aaagaauggg uccugcaaac ggggaccccg cacccacuau      420

ggccaaaagg ccauucuguu ucucccucug cccgugucua gcgacuga                   468


<210>  644
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  644
auggugggcg ucgggggagg cgacguugag gaugugaccc ccagaccugg gggaugccag       60

aucagcggcc gcggggcccg gggauguaac ggcauuccgg gcgcugccgc gugggaagcu      120

gcccugccca gacggcgccc uagacggcac cccuccguga auccucgcuc uagagccgcu      180

gggagccccc ggacacgcgg aagacggacg gaggaacgcc cuuccggcuc uagacucggg      240

gaccggggac gcggcagagc ccugcccggg ggacggcuug gcggcagagg gcgcggacgg      300

gcucccgaga gagucggcgg gcgcggacgg ggcagaggga ccgccgcgcc ucgcgccgcu      360

cccgccgcuc ggggaagcag accuggcccc gccggcacaa uggcggccgg guccaucacc      420

acacugccgg cucucccuga agauggaggc ucuggggccu ucccgccugg acauuuuaag      480

gaccccaaac gccuguacug caagaacggc ggguucuuuc uucggauuca ccccgauggc      540

agaguggacg gaguucgcga gaaaagcgau ccucauauca agcugcaacu ccaggcugag      600

gaacggggcg uggucuccau uaaaggggug ugugccaaua gauaucuggc caugaaggag      660

gacggacggc ugcucgcuag caagugcguu accgaugaau guuucuuuuu cgagcgccug      720

gagucuaaca auuacaacac auauagaucc cggaaauaca ccagcuggua uguggcgcuu      780

aagagaacgg gccaguacaa acuggggucu aagaccggac cgggccagaa agccauccuc      840

uuucugccca uguccgcuaa gagcuga                                          867


<210>  645
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  645
augcacaagu ggauccugac cuggauucuc cccacacugc uuuacagaag cugcuuccau       60

aucauuuguc uggugggcac gaucucccuc gccugcaacg acaugacccc ugagcagaug      120

gcuacaaaug ucaacuguuc uagcccggaa cggcacaccc gcuccuauga uuacauggaa      180

gggggagaca uuagaguucg gcgccuguuu ugcagaacac aaugguaucu ucggaucgau      240

aaacgcggca aggugaaagg gacccaggag augaagaaua acuacaauau cauggagauu      300

agaacagugg ccgucggaau cguggcgauu aaaggcguug aaucugaguu cuaucuggcu      360

augaacaagg aggggaagcu cuacgccaaa aaggaaugua augaggacug caacuuuaaa      420

gaacugaucc uggagaauca uuauaacacc uacgccagcg cuaaguggac gcacaaugga      480

ggcgagaugu ucguggcccu caaccagaaa ggcauucccg uccgggggaa gaagaccaaa      540

aaggaacaga aaacagcuca uuuucugccu auggccauca ccuga                      585


<210>  646
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  646
augaagcugc uccccagcgu gguccugaaa cuuuuccugg ccgcuguucu cuccgcccug       60

gugaccggcg agucucuuga aagacugcgg cgcgggcucg cggcuggaac aagcaacccu      120

gacccgccca cgguguccac cgaucagcug cugccucucg gcgggggaag agaccggaag      180

guccgcgauc ugcaagaggc cgaccuugau cugcucagag ugacacuguc uagcaaaccc      240

caggcccuug cuaccccuaa uaaggaggaa cacggcaaac ggaagaagaa agggaaggga      300

cugggcaaaa agcgcgaccc cugccucaga aaauacaagg auuuuuguau ccauggcgaa      360

ugcaaguaug uuaaagagcu gcgggccccu uccuguauuu gccacccggg guaccaugga      420

gagcgcuguc acggccuguc ucuccccgug gaaaacagac uguauacaua cgaccauacc      480

acaauccuug cugucguggc cguugugcug agcuccgucu gccuccuggu gauugugggg      540

cuucugaugu uccgguauca ccgcagagga ggcuacgaug ucgagaauga agagaagguu      600

aaacucggga ugaccaacag ccacuga                                          627


<210>  647
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  647
auguggguga ccaagcugcu ccccgcccug cuucugcagc acguccuccu gcaucuucug       60

cuccugccua ucgcuauucc guacgccgag ggccaaagaa aacggcgcaa cacaauccac      120

gaguucaaga aaagcgcgaa gacgacccug auuaaaaucg accccgcucu caagauuaag      180

accaaaaagg uuaauaccgc cgaucagugc gccaacagau guacacggaa uaaagggcug      240

ccuuuuaccu gcaaggcuuu cguguuugac aaagcccgca agcagugucu uugguucccc      300

uuuaacucca ugucuagcgg agugaagaaa gaguucggcc augaauuuga ucuguaugag      360

aauaaggacu acaucagaaa cugcaucauu gggaaaggac gguccuauaa gggcacaguc      420

ucuaucacca aaagcgggau uaagugucag ccuugguccu cuaugauccc ccacgaacau      480

agcuuccucc cuuccagcua ccgcggaaaa gaucugcaag agaauuauug cagaaacccg      540

cggggcgagg aaggcgggcc cugguguuuu acgucuaauc cugaggugcg cuacgaaguu      600

ugcgacauuc cccaguguuc cgagguggag ugcaugaccu guaacggaga aagcuauaga      660

ggccuuaugg aucacacaga gucugggaag aucugccagc ggugggacca ccagaccccu      720

caucgccaca aguuccugcc cgaaagauac ccggauaaag gauuugacga uaauuacugc      780

cggaacccug acggccaacc ccgcccuugg uguuauacac ucgaucccca uacaagaugg      840

gaauacugcg cuauuaagac gugugccgac aauacaauga acgacaccga ugucccccug      900

gaaacaaccg agugcaucca ggggcaggga gagggcuauc ggggcaccgu gaauacaauc      960

uggaacggga uuccuuguca gagaugggac ucccaauacc cgcacgaaca cgauaugacg     1020

cccgagaacu ucaaaugcaa ggaccugcgc gaaaauuauu gucggaaccc ugauggaagc     1080

gagucucccu ggugcuuuac cacagacccu aauaucagag uuggcuacug uucccagauu     1140

cccaacugcg auaugagcca ugggcaggac uguuaucgcg gaaauggcaa aaacuacaug     1200

gggaaucucu cccaaacccg gucuggacug acaugcagca ugugggauaa gaacauggaa     1260

gaccuucaca gacauaucuu cugggagccg gaugcgucca agcugaauga gaacuacugc     1320

cgcaauccug acgacgaugc ccacggcccc ugguguuaua ccggcaaccc ucucauuccc     1380

ugggacuacu gcccuaucag ccggugugaa ggggauacga cacccaccau cgugaaucug     1440

gaccauccgg ucauuucuug cgcuaaaacc aagcagcuua gaguggugaa cggaaucccu     1500

acacgcacca auauuggcug gauggucucc cugcgguaua gaaacaaaca caucuguggg     1560

ggaagccuca uuaaggaguc uuggguucug acagcccgcc agugcuuccc cagccgggau     1620

cugaaagacu acgaggcuug gcucggcauc cacgaugugc augggagagg cgacgaaaag     1680

uguaaacagg ugcugaacgu cucccaacuu guguauggac ccgaaggcuc ugaucugguu     1740

cucaugaagc uggcccggcc ugcggugcuu gacgauuuug ucagcacgau cgaccugccg     1800

aauuacgggu gcaccauucc cgagaagaca uccuguagcg uguauggaug gggcuacacc     1860

gggcucauca acuacgaugg acugcugcgc guugcccacc ucuauauuau gggcaaugag     1920

aaaugcucuc agcaucacag agggaaggug acacugaacg aauccgagau cugugcuggc     1980

gccgagaaaa uuggaagcgg cccuugcgaa ggggacuacg gaggcccccu ugucugcgag     2040

cagcacaaga ugcggauggu gcuggggguc aucgugccug gaagaggcug ugcuauuccc     2100

aaucgcccug ggaucuucgu ucggguggcc uauuacgcca aguggaucca uaaaauuauc     2160

cucaccuaua agguccccca gucuuga                                         2187


<210>  648
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  648
auggccaagg cugccgcgau cggcauugac cuggggacca cauacagcug cgugggaguc       60

uuccagcacg gcaaaguuga gaucauugcu aacgaucaag ggaauagaac gacccccucc      120

uauguggccu uuacagacac cgaacggcuc aucggagaug ccgcuaagaa ccagguggcc      180

cugaauccuc agaacacagu cuucgacgcu aaacgccuua uuggcagaaa guuuggggau      240

ccggugguuc agucugacau gaaacauugg cccuuccaag ugaucaauga uggagacaag      300

ccuaaggucc aggugagcua caaaggcgag accaaggccu uuuaucccga agagaucucc      360

ucuaugguuc ugacaaaaau gaaggaaauu gcggaggccu accucggcua uccugugacc      420

aacgcuguca ucacggugcc cgccuacuuc aaugauagcc agcggcaggc uaccaaagac      480

gccgggguga uugcgggacu gaacguccuu cgcaucauua augagccuac agccgcugcc      540

aucgcuuaug gccuggauag aaccgggaag ggagaacgga acguucucau uuuugaccug      600

ggcgggggaa cauucgaugu guccauccug accaucgacg acggcauuuu ugaggugaag      660

gccacggccg gcgauacaca ccucggggga gaagacuucg auaaucgccu ggucaaccau      720

uuuguggagg aguucaaaag aaagcacaaa aaggacaucu cucaaaauaa acgggcuguu      780

cgcagacuuc ggaccgcgug ugaacgcgcc aagagaacac ugagcuccag cacccaggcu      840

ucucucgaga uugauucccu guuugaaggc aucgacuucu acaccagcau uacacgggcc      900

cgcuucgagg aacuuugcuc ugaucuguuu agauccacgc ucgagccggu ggagaaagcc      960

cugcgggacg cuaagcugga uaaggcccag auccaugacc ucguccuggu ugggggaagc     1020

accagaaucc ccaaagugca gaaacuucug caagauuucu uuaacggccg cgaccucaau     1080

aagucuauua acccugacga agcgguggcu uacggggccg ccguccaggc ugccauccug     1140

augggagaua aguccgagaa cgugcaggac cuucugcucc uggaugucgc uccccugagc     1200

cucggccugg aaacagccgg cggggugaug accgcgcuua uuaaacggaa uagcacaauc     1260

ccuaccaagc aaacgcagau uuucacaacc uauucugaca accagcccgg aguucugauc     1320

cagguguacg agggcgaaag agccaugacc aaggauaaua accuccuggg gcgcuuugag     1380

cuuagcggaa ucccgccugc uccccggggc gucccucaaa uugaggugac auucgacauc     1440

gaugccaaug ggauucugaa cguuaccgcu acagacaaau ccacgggcaa ggccaauaaa     1500

aucaccauua caaacgauaa gggaagacuc agcaaagaag agaucgaacg cauggugcag     1560

gaggcggaaa aguauaaggc cgaggacgag guccagcggg aaagaguguc ugcuaaaaau     1620

gcccuggagu ccuacgcuuu uaacaugaag uccgccgugg aagaugaggg ccugaaaggg     1680

aagauuucug aggccgacaa aaagaagguu cucgauaaau gucaggaagu caucagcugg     1740

cuggacgcua auacccuugc ggagaaggac gaguucgaac acaaacgcaa ggaacuggag     1800

caagugugca accccaucau uuccggacuc uaucagggcg ccgggggacc cggcccuggg     1860

ggcuuuggag cucagggccc gaaaggggga ucuggcagcg ggcccacaau cgaggaagug     1920

gauuga                                                                1926


<210>  649
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  649
auggccaagg cugccgcgau cggcauugac cuggggacca cauacagcug cgugggaguc       60

uuccagcacg gcaaaguuga gaucauugcu aacgaucaag ggaauagaac gacccccucc      120

uauguggccu uuacagacac cgaacggcuc aucggagaug ccgcuaagaa ccagguggcc      180

cugaauccuc agaacacagu cuucgacgcu aaacgccuua uuggcagaaa guuuggggau      240

ccggugguuc agucugacau gaaacauugg cccuuccaag ugaucaauga uggagacaag      300

ccuaaggucc aggugagcua caaaggcgag accaaggccu uuuaucccga agagaucucc      360

ucuaugguuc ugacaaaaau gaaggaaauu gcggaggccu accucggcua uccugugacc      420

aacgcuguca ucacggugcc cgccuacuuc aaugauagcc agcggcaggc uaccaaagac      480

gccgggguga uugcgggacu gaacguccuu cgcaucauua augagccuac agccgcugcc      540

aucgcuuaug gccuggauag aaccgggaag ggagaacgga acguucucau uuuugaccug      600

ggcgggggaa cauucgaugu guccauccug accaucgacg acggcauuuu ugaggugaag      660

gccacggccg gcgauacaca ccucggggga gaagacuucg auaaucgccu ggucaaccau      720

uuuguggagg aguucaaaag aaagcacaaa aaggacaucu cucaaaauaa acgggcuguu      780

cgcagacuuc ggaccgcgug ugaacgcgcc aagagaacac ugagcuccag cacccaggcu      840

ucucucgaga uugauucccu guuugaaggc aucgacuucu acaccagcau uacacgggcc      900

cgcuucgagg aacuuugcuc ugaucuguuu agauccacgc ucgagccggu ggagaaagcc      960

cugcgggacg cuaagcugga uaaggcccag auccaugacc ucguccuggu ugggggaagc     1020

accagaaucc ccaaagugca gaaacuucug caagauuucu uuaacggccg cgaccucaau     1080

aagucuauua acccugacga agcgguggcu uacggggccg ccguccaggc ugccauccug     1140

augggagaua aguccgagaa cgugcaggac cuucugcucc uggaugucgc uccccugagc     1200

cucggccugg aaacagccgg cggggugaug accgcgcuua uuaaacggaa uagcacaauc     1260

ccuaccaagc aaacgcagau uuucacaacc uauucugaca accagcccgg aguucugauc     1320

cagguguacg agggcgaaag agccaugacc aaggauaaua accuccuggg gcgcuuugag     1380

cuuagcggaa ucccgccugc uccccggggc gucccucaaa uugaggugac auucgacauc     1440

gaugccaaug ggauucugaa cguuaccgcu acagacaaau ccacgggcaa ggccaauaaa     1500

aucaccauua caaacgauaa gggaagacuc agcaaagaag agaucgaacg cauggugcag     1560

gaggcggaaa aguauaaggc cgaggacgag guccagcggg aaagaguguc ugcuaaaaau     1620

gcccuggagu ccuacgcuuu uaacaugaag uccgccgugg aagaugaggg ccugaaaggg     1680

aagauuucug aggccgacaa aaagaagguu cucgauaaau gucaggaagu caucagcugg     1740

cuggacgcua auacccuugc ggagaaggac gaguucgaac acaaacgcaa ggaacuggag     1800

caagugugca accccaucau uuccggacuc uaucagggcg ccgggggacc cggcccuggg     1860

ggcuuuggag cucagggccc gaaaggggga ucuggcagcg ggcccacaau cgaggaagug     1920

gauuga                                                                1926


<210>  650
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  650
auggccaccg cuaagggcau cgccauuggg aucgaccugg gaacaacgua cagcugcgug       60

ggcgucuucc agcacgggaa gguugagauu aucgcgaacg aucaaggaaa uagaaccaca      120

cccuccuaug uggcuuuuac cgacacagaa cggcucauug gcgaugccgc caagaaccag      180

guggcuauga auccucagaa caccgucuuc gacgccaaac gccugaucgg gagaaaguuu      240

aaugauccgg ugguucaggc ugacaugaaa cuuuggcccu uccaagugau caacgaggga      300

ggcaagccua agguccuggu gucuuacaaa ggcgaaaaua aggccuuuua ucccgaggaa      360

auuagcucca ugguucucac aaaacugaag gagaccgcgg aggccuuccu ugggcauccu      420

gugacgaacg cugucaucac cgugcccgcc uacuuuaaug auucucagcg gcaggcuaca      480

aaagacgccg gagugauugc gggccugaac guccuccgca ucauuaauga accuaccgcc      540

gcugccaucg cuuaugggcu ggauaaggga ggccaggggg agagacacgu ucugauuuuc      600

gaccucggag gcggcacauu ugaugugagc auccugacca ucgacgaugg gauuuucgaa      660

gugaaggcca cggccggaga cacacaucuu ggcggggagg acuuugauaa ccggcugguc      720

ucccacuucg uggaggaauu uaaacgcaag cauaaaaagg acaucucuca aaauaaaaga      780

gcuguucggc gccucagaac cgcgugugag cgggccaagc gcacacugag cuccagcacc      840

caggcuaacc uugaaauuga uucucuguac gagggaaucg acuucuauac cuccauuaca      900

agagcccggu ucgaggaacu cugcgccgau cuguuucgcg gcacgcugga gccgguggaa      960

aaagcucuca gagacgccaa gauggauaag gcgaaaaucc acgacaucgu ccugguuggg     1020

ggaagcaccc ggauucccaa ggugcagaga cuucugcagg auuacuucaa uggccgcgac     1080

cucaacaaau cuaucaaccc ugaugaggcu guggccuacg gcgccgcugu ccaagccgcu     1140

auucugaugg gggacaaguc cgaaaaagug caggaccuuc ugcuccugga ugucgcgccc     1200

cugagccucg gacuggagac agccggcggg gugaugaccg cccuuaucaa gcggaauagc     1260

acaauuccua ccaagcagac gcaaaucuuu acaaccuauu ccgacaacca gcccggaguu     1320

cugauccagg uguacgaagg cgagagagcu augaccaaag auaauaaccu ccuggggcgc     1380

uucgaccuua caggcauucc gccugcuccc cggggagucc cucagaucga ggugaccuuu     1440

gauauugacg ccaauggcau ccugaacguu acagccacgg auaagagcac cgggaaagug     1500

aauaagauua caaucaccaa cgacaaagga agacucucca aggaagagau ugaacgcaug     1560

guccuggaug cggagaagua uaaagccgaa gacgaggugc aacgggagaa gaucgcugcc     1620

aaaaaugcuc uggaaucuua cgccuucaac augaagucug ugguuuccga ugagggccuc     1680

aaagggaaga ucagcgaauc ugacaagaau aaaauucugg auaaguguaa cgagcuucug     1740

uccuggcucg aggucaauca gcuggccgaa aaagacgagu uugaccacaa gagaaaagaa     1800

cuggagcaga ugugcaaccc caucauuaca aaacuuuauc agggaggcug uaccgggccc     1860

gcuugcggca cgggauacgu gccuggccgc ccggcgaccg ggcccacaau cgaagaggug     1920

gauuga                                                                1926


<210>  651
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  651
augagcgcca gaggccccgc uaucgggauu gaccugggaa ccacauacuc cugcgugggc       60

gucuuccagc acgggaaggu ugagaucauu gccaacgauc aaggaaaucg gacgaccccu      120

ucuuaugugg cguuuacaga caccgaacgc cucaucggcg augcugccaa aaaccaggug      180

gccaugaauc cgacaaacac cauuuucgac gcuaagagac ugaucgggcg gaaauuugag      240

gaugccacag uccagagcga caugaagcau uggcccuucc gcgugguuuc cgaaggaggc      300

aaaccuaagg ugcaggucga guacaagggc gaaaccaaaa cguuuuuccc cgaggagauc      360

ucuagcaugg ugcuuaccaa gaugaaagaa auugcugagg ccuaucuggg aggaaagguu      420

cacuccgcgg ugaucacagu cccugccuac uuuaaugauu cucaaagaca ggcuaccaaa      480

gacgccggca caauuaccgg gcucaacgug cugcggauca uuaaugaacc cacggcugcc      540

gcgaucgccu auggacuuga uaagaagggc ugugcugggg gagagaaaaa cgugcugauu      600

uucgaccucg gcggcgggac auuugauguc agcauccuga ccaucgagga cggaauuuuc      660

gaaguuaagu ccacagccgg cgauacccau cuugggggag aggacuuuga caaucgcaug      720

gugagccacc ucgcugaaga guucaaaaga aagcauaaaa aggauaucgg cccuaacaaa      780

cgggccgugc gcagacugcg gaccgccugc gaacgcgcua agagaacacu uucuuccagc      840

acgcaggcgu cuauugagau cgacucccug uacgaggggg ucgauuuuua uaccagcauu      900

acacgggccc gcuucgagga acucaaugcu gaccuguuca gaggaacccu ugaaccggug      960

gagaaggccc ugcgggaugc caaacucgac aagggccaga uccaagaaau cguucuggug     1020

ggcgggucua cacgcauucc caaaauccag aagcugcucc aggacuuuuu caacggaaaa     1080

gagcugaaua aguccauuaa cccugaugag gcugucgccu acggcgcggc ugugcaggcc     1140

gccauccuua uuggggauaa gagcgaaaau guucaagacc ugcuccugcu ugaugugacg     1200

ccccuguccc ucggaaucga gaccgcuggc ggggucauga caccucugau caaaagaaac     1260

accaccauuc ccacaaagca gacccagaca uuuacgaccu acucugacaa ccaaagcucc     1320

gugcuggucc agguguauga aggcgagcgg gccaugacaa aagacaauaa ccuccuggga     1380

aaguucgauc uuaccggcau cccgccugcu cccagagggg uuccucagau ugaagugaca     1440

uuugacaucg augccaaugg gauucugaac gucaccgcgg ccgacaaaag cacgggcaag     1500

gagaauaaga ucaccauuac aaacgauaaa gggcgccucu cuaaggacga uaucgaccgg     1560

auggugcagg aggcugaaag auacaaaucc gaggaugaag ccaaucgcga ccggguugcu     1620

gccaagaacg cgcuggagag cuauaccuac aauaucaaac aaacagugga ggaugaaaag     1680

cugagaggaa agauuucuga gcaggacaaa aacaagaucc uggauaaaug ucaggaaguc     1740

auuaauuggc ucgaccgcaa ccagauggcc gagaaggacg aauaugagca caaacaaaag     1800

gagcuggaac gggugugcaa ucccaucauu agcaaacugu accagggcgg gcccggcgga     1860

ggcuccgggg gaggcggguc uggagcuagc ggcgggccua ccaucgagga aguggauuga     1920


<210>  652
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  652
augagcgugg ucggcaucga ccugggguuc caguccugcu acguugccgu ggcuagagcc       60

ggaggcauug agaccaucgc gaacgaauau ucugaucggu guacacccgc uugcauuagc      120

uuugggccua agaaucgcuc caucggagcc gccgcuaaau cucaagugau uagcaacgcc      180

aagaauacgg uccagggcuu caaaagauuu cacgggcggg cuuucuccga cccguuugug      240

gaggccgaaa agucuaaccu cgcguacgau aucguucagc ugcccaccgg acuuacaggc      300

aucaaaguga ccuauaugga ggaagaacgc aauuucacaa ccgagcaggu cacagccaug      360

cugcucagca agcugaagga aaccgcugag uccgugcuua aaaagccugu uguggacugu      420

gucgugagcg ugcccugcuu uuacacggau gccgaaagac ggucugucau ggacgcuacc      480

caaauugccg gccugaacug ucuccgccug augaaugaga caaccgcggu ugcccuggcu      540

uaugggaucu acaaacagga ucucccugcc cuggaggaaa agcccagaaa cgugguguuc      600

gucgacaugg gacauuccgc uuaucaggug agcguuugcg ccuuuaaucg gggcaaacuu      660

aaggugcugg ccacagcuuu cgauaccacg cucgggggac gcaaguuuga cgagguccug      720

gugaaccacu ucugugaaga guuuggcaaa aaguacaaac uugauauuaa gucuaaaauc      780

agagcgcugc uccggcuguc ccaggaaugc gagaagcuga aaaagcucau gagcgccaau      840

gcuucugacc ugccucuuuc cauugagugu uucaugaacg auguugacgu gagcgggaca      900

augaaucgcg gaaaguuccu ggaaaugugc aacgaccucc uggccagagu cgagccgccc      960

cuucgguccg ugcuggaaca aaccaaacuc aagaaagagg auaucuacgc cgucgaaauu     1020

gugggcggcg cuacacgcau cccugccguu aaggagaaaa ucucuaaguu uuucgggaag     1080

gagcugagca ccacccugaa ugcggacgaa gcugugacaa gaggaugugc ccuccagugc     1140

gccauucugu cccccgcuuu uaaaguccgg gaguucagca ucacggaugu gguuccuuau     1200

cccauuucuc uuagauggaa cuccccggcc gaagagggca gcucugacug cgaaguguuu     1260

agcaagaacc augcugcccc uuucuccaaa guccugaccu uuuaccgcaa ggagcccuuc     1320

acacucgagg cguauuacuc uagcccucag gaucugcccu aucccgaccc ugccaucgcu     1380

caguuuuccg ugcaaaaagu gaccccgcag agcgaugggu cuuccagcaa gguuaagguc     1440

aaagugcggg ugaaugucca cggaauuuuc ucugugucca gcgccucccu uguugaagug     1500

cauaagucug aggaaaacga ggagcccaug gaaacagacc agaaugcuaa agaggaagag     1560

aagaugcaag ucgaucagga ggagccucac guggaggaac agcagcaaca gacccccgcc     1620

gagaacaaag cggaaagcga ggaaauggag acgucccagg ccggcucuaa ggacaagaaa     1680

auggaucagc cuccccaagc uaagaaagcc aagguuaaaa caagcaccgu ggaccugccg     1740

aucgagaauc agcuccugug gcagaucgac agagaaaugc ugaaccucua cauugagaau     1800

gaagggaaga ugaucaugca ggauaaacug gagaaggaac gcaacgacgc uaagaaugcc     1860

gucgaggagu auguguacga aaugcgggau aaacuuuccg gagaguacga aaaguuuguu     1920

agcgaggacg auagaaacuc uuucacccug aaacucgagg acacagaaaa uuggcuguau     1980

gaggauggcg aagaccaacc uaaacaggug uacgucgaua agcuggccga gcuuaagaac     2040

cucggccagc ccauuaagau ccgcuuucag gaauccgagg agcggccuaa acuguucgag     2100

gaacugggga agcaaauuca gcaguauaug aaaaucauca gcucuuucaa gaauaaagaa     2160

gaccaauacg aucaccucga cgcugcggau augaccaagg uggagaaguc cacaaacgaa     2220

gccauggagu ggaugaauaa caaacugaac cuucagaaua agcagagccu gacgauggac     2280

cccgugguca aaucuaagga gauugaagcu aaaaucaagg agcucaccag cacauguucc     2340

ccuauuauca gcaagcccaa accgaagguu gaaccuccca aagaggaaca gaagaacgcc     2400

gagcaaaaug gacccgugga cggccagggg gauaacccug gaccgcaggc cgcugagcag     2460

ggcaccgaca cagccgugcc cucugauucc gacaaaaagc ugccugaaau ggauauugac     2520

uga                                                                   2523


<210>  653
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  653
augagcgugg ucggcaucga ccugggguuc cucaacugcu acauugccgu ugcuagaucc       60

ggaggcaucg agaccauugc caaugaauau ucugaucggu guacacccgc gugcaucagc      120

cugggguccc gcacgagagc uauuggaaac gccgccaagu cucagaucgu gaccaaugug      180

cggaacacaa uccacggcuu uaaaaagcug caugggcgca gcuucgacga uccuauuguc      240

caaaccgaga gaauccggcu uccguacgaa cuccagaaaa ugcccaaugg auccgcuggc      300

gugaagguuc gcuaucugga ggaagagaga ccuuuugcca uugaacaggu gacaggcaug      360

cuucuggcua aacucaagga gaccucugag aacgcccuga agaaacccgu cgcggacugu      420

gugaucagca uuccuuccuu cuuuacagau gccgaacggc gcagcguuau ggcugccgcu      480

cagguggccg ggcugaauug ccucagacug augaacgaga ccacggcggu cgcccuugcu      540

uacggaaucu auaagcaaga ccugcccccu cucgaugaga aaccgcggaa ugugguguuc      600

auugacaugg gccacucugc cuaccagguc cugguuugug cuuuuaacaa ggggaaacuu      660

aaggugcugg ccaccacauu cgaucccuau cucggaggcc gcaauuuuga cgaagcccug      720

guggauuacu ucugcgacga guuuaagacc aaauacaaga ucaacgucaa agaaaauucc      780

agagcucugc uccggcugua ucaggagugu gaaaaacuua agaagcugau gagcgcgaac      840

gccucugauc ucccucugaa uaucgagugc uucaugaacg accuugacgu guccagcaaa      900

augaaccgcg cucaguuuga gcaacugugu gccucucucc uggccagagu ugaacccccu      960

cugaaggcug ugauggagca ggccaaucuc cagcgggaag auauuuccag caucgagauu     1020

gucgggggag cgacaagaau ccccgcugug aaggaacaga uuaccaaauu cuuccugaag     1080

gacaucucca cgacacuuaa cgccgaugag gccguugcuc gcggcugcgc ccugcaaugu     1140

gcuauccucu cuccggccuu uaaagugcgg gaguucagca uuaccgaccu ggucccuuac     1200

uccaucacac uuagauggaa gaccagcuuu gaagauggcu cuggggagug cgaaguguuc     1260

ugcaaaaauc aucccgcgcc uuuuuccaag gucauuaccu uccacaagaa agagcccuuu     1320

gaacuggagg ccuucuauac aaaccuccau gaggugcccu acccugacgc ucgcaucggc     1380

agcuuuacga uucagaaugu uuucccgcag ucugauggag acagcuccaa ggugaaaguc     1440

aaggugcggg uuaacaucca cgggaucuuu ucuguggcca gcgcuuccgu cauugaaaaa     1500

caaaaucugg agggagauca cagcgacgcc cccauggaaa ccgagacauc uuucaagaac     1560

gagaauaagg auaacaugga caaaaugcaa guggaccagg aagagggcca ucagaagugu     1620

cacgcggaac auaccccuga ggaagagauc gaucacacag gggccaaaac caaguccgcu     1680

gugagcgaca aacaggauag acugaaucag acgcucaaga agggaaaagu uaagucuauu     1740

gaccugccca uccaguccag ccuuugccgc cagcugggcc aagaucuccu gaacuccuau     1800

auugagaaug aaggcaaaau gaucaugcag gacaagcugg agaaagaacg gaacgaugcc     1860

aagaaugcug ucgaggaaua cguguaugac uuuagagauc gccuugggac aguguacgag     1920

aaauucauua ccccugagga ccucucuaag cugagcgccg uccuggaaga uaccgagaac     1980

uggcucuacg aagacggaga ggaucagccc aaacaggugu auguugacaa gcugcaagaa     2040

cuuaagaaau acggccagcc gauccagaug aaguauaugg agcacgagga acggccuaaa     2100

gcccugaacg accucgggaa gaagauccag cuggugauga aagucauuga ggcuuacaga     2160

aauaaggaug aacgcuauga ccaucuggau cccacagaga uggagaaagu ggaaaagugu     2220

aucuccgacg cgaugucuug gcuuaacagc aaaaugaaug cccaaaacaa gcucucccug     2280

acccaggauc cuguugugaa ggucagcgag auuguggcua aaucuaagga acuggacaau     2340

uucugcaacc ccaucauuua caaaccuaag cccaaagccg agguuccgga agauaagccu     2400

aaggccaauu ccgagcacaa cggacccaug gacggccaga gcgggacaga gacgaaaucu     2460

gauuccacca aggacagcuc ucaacauaca aaaagcuccg gcgaaaugga gguggauuga     2520


<210>  654
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  654
augaagcuga gccucguggc cgcuaugcug cuucugcucu ccgccgcgag agcugaggaa       60

gaggacaaaa aggaagaugu cggcaccguu guggggaucg accugggaac aacguacucu      120

ugcgugggcg ucuucaaaaa cgggcgggug gagauuaucg ccaaugauca gggaaaccgc      180

auuaccccca gcuauguugc cuuuacaccu gaaggcgaga gacuuaucgg ggacgcugcc      240

aagaaucaac ugaccuccaa cccggagaau acaguguucg augcuaaacg gcucauugga      300

cgcaccugga acgaccccuc uguccagcag gauaucaagu uucugccuuu caaggugguu      360

gaaaagaaga caaaacccua cauccaggug gacauuggcg gcgggcaaac caagacguuu      420

gccccugagg aaaucagcgc gaugguccug accaaaauga aggagacagc cgaggcuuau      480

cucggaaaga aagugaccca cgccgugguc acaguucccg cuuacuucaa ugaugcccag      540

agacaggcga ccaaggacgc cggcacgauu gcugggcuga acgugaugcg gaucauuaau      600

gaaccuacag ccgcugccau cgccuaugga cuugauaaac gcgagggcga aaagaacauu      660

cugguguuug accucggggg aggcaccuuc gaugucuccc ugcuuacaau cgacaauggc      720

guguuugagg uuguggcuac caacggggac acccaucugg gaggcgaaga uuucgaccag      780

agagucaugg agcacuuuau caaacucuac aagaaaaaga cagggaagga ugugcggaaa      840

gacaaucgcg cgguucaaaa gcugagacgg gagguggaaa aagccaagcg cgcucugucu      900

agccagcauc aggccagaau ugagaucgaa uccuucuaug agggagaaga uuuuagcgag      960

acgcucaccc gggccaaauu cgaggaacug aacauggacc uuuuccgcuc uacaaugaag     1020

ccgguccaga aggugcugga ggauuccgac cucaaaaaga gcgauauuga cgaaaucguc     1080

cuggugggcg ggucuacccg gauucccaaa auccaacagc uuguuaagga guuuuucaau     1140

ggaaaagaac cuuccagagg caucaacccc gaugaggcug uggccuacgg cgcggcuguc     1200

caggccgggg ugcugagcgg agaccaagac acaggcgauc ucguucugcu ggacgugugu     1260

ccucucaccc uggggauuga gacggucgga ggcgugauga caaaacuuau ccccagaaac     1320

accgugguuc cgaccaagaa aucucagauc uuuuccacag ccagcgauaa ucagccuacc     1380

gucacaauua agguguacga aggggagcgc ccccugacga aagacaacca ccuccugggc     1440

accuucgauc uuacaggcau uccucccgcu ccccggggag ugccucagau cgaagucacc     1500

uuugagaucg acgugaaugg gauucugaga guuacagccg aggauaaggg aaccggcaac     1560

aaaaauaaga ucacgauuac caacgaccaa aaucgccuca caccggaaga gaucgaacgg     1620

auggugaacg augcugagaa guucgccgaa gaggacaaaa agcugaaaga gagaauugau     1680

acccgcaaug aacuggaguc cuaugcguac ucucucaaga accagaucgg ggacaaagaa     1740

aagcugggag gcaaacuuag cuccgaggau aaggaaacaa uggagaaggc cgucgaggag     1800

aaaauugaau ggcuggaaag ccaucaggac gcugacaucg aggauuuuaa ggccaaaaag     1860

aaagaacucg aggagaucgu gcagcccauu aucucuaagc uguauggguc cgcuggcccu     1920

cccccuaccg gagaagagga cacggccgaa aaggaugagc uguga                     1965


<210>  655
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  655
augcaggccc ccagagagcu ggcugugggc aucgaccucg ggaccacaua cagcugcguc       60

ggaguuuucc aacagggccg gguggaaauu cuggccaacg aucaggggaa ucgcacgacc      120

ccuuccuaug uggcguuuac agacaccgag agacuugucg gagaugcugc caagucucag      180

gccgcucuga acccgcacaa uacaguguuc gacgccaaac ggcucaucgg ccgcaaguuu      240

gcugauacca caguucaaag cgacaugaaa cauuggcccu ucagaguggu cuccgaaggg      300

ggaaagccua aagugcgggu uuguuaccgc ggcgaggaua agaccuuuua ucccgaagag      360

auuucuagca uggugcuguc caagaugaaa gagacggccg aagcguaccu uggccagccu      420

gucaagcacg ccgugaucac cgugcccgcu uauuucaacg acucucagag acaggccaca      480

aaagaugcug gggccauugc gggacugaau guccuccgga ucaucaacga gccuaccgcc      540

gcugccauug cuuacggccu ggaccgcaga ggggccggag aacggaaugu ucugaucuuu      600

gaucucggcg ggggaacauu cgacgugagc gugcugucca uugaugccgg cgucuuugag      660

gugaaggcua ccgcgggcga cacgcaucuu gggggagagg acuucgauaa ccgccugguu      720

aaucacuuua uggaagaguu cagacggaaa cauggcaagg accucagcgg gaacaagcgc      780

gcccugagac ggcuuagaac agcuugcgaa cgcgccaaac ggacccuguc uuccagcaca      840

caagccaccc ucgagaucga uucucuguuu gaaggagugg acuucuauac cuccauuaca      900

agagcucgcu ucgaggagcu guguagcgau cucuuucggu cuacgcugga accggucgag      960

aaggcccuua gagacgcgaa acuggauaag gcucagaucc acgacguggu ucucgugggc     1020

ggguccaccc gcauucccaa aguccagaag cugcuucagg auuucuuuaa uggaaaagaa     1080

cugaacaaga gcaucaaucc ugacgaggcc guggccuacg gcgcugccgu ccaagcugcc     1140

gugcucaugg gcgauaagug cgaaaaaguu caggaccugc ugcuccugga cguggcgccc     1200

cuuucccugg ggcucgagac agccggaggc gucaugacca cacugaucca gcggaacgcu     1260

accauuccua cgaagcaaac acagaccuuc accacauacu cugauaauca gcccggggug     1320

uuuauccagg uuuaugaggg agaaagagcc augaccaaag acaacaaccu ucugggccgc     1380

uucgagcuca gcgggauucc gccugcuccc cggggcgugc cucaaaucga agucacauuu     1440

gauauugacg ccaauggaau ccuguccgug acggcgaccg auagaagcac aggcaaggcc     1500

aacaaaauca ccauuacaaa ugacaagggg cgccugucua aggaggaagu ggagcggaug     1560

guucacgagg cugaacagua caaagccgag gaugaagcuc agagagaccg ggucgccgcc     1620

aagaacuccc ucgaggcuca uguguuccac gugaaaggaa gccugcagga ggaaucucuu     1680

cgcgauaaga uccccgagga agacagacgg aaaaugcaag auaaguguag agagguccug     1740

gcguggcucg aacauaauca gcuggccgag aaggaggaau augagcacca gaaacgcgaa     1800

cuggagcaga uuugccggcc caucuuuagc agacuuuacg gcgggccugg agugccgggc     1860

ggguccucuu guggcaccca agcucgccag ggagacccca gcacgggccc uauuaucgaa     1920

gagguugauu ga                                                         1932


<210>  656
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__P48741__HsHSPA7

<400>  656
augcaggccc ccagagagcu ggcugugggc aucgaccucg ggaccacaua cagcugcguc       60

ggaguuuucc aacagggccg gguggaaauu cuggccaacg aucaggggaa ucgcacgacc      120

ccuuccuaug uggcguuuac agacaccgag agacuugucg gagaugcugc caagucucag      180

gccgcucuga acccgcacaa uacaguguuc gacgccaaac ggcucaucgg ccgcaaguuu      240

gcugauacca caguucaaag cgacaugaaa cauuggcccu uccagguggu cuccgaaggg      300

ggaaagccua aagugagagu uuguuaccgg ggcgaggaua agaccuuuua ucccgaagag      360

auuucuagca uggugcuguc caagaugaaa gagacggccg aagcguaccu uggccagccu      420

gucaagcacg ccgugaucac cgugcccaca uauuucucua acagccagcg ccaagcuacc      480

aaagacgccg gggcuauugc cggacugaag guccucccua ucaucaauga ggcgacagcc      540

gcugccauug cuuacggccu ggauagacgc ggggccggaa aacggaacgu ucugaucuuu      600

gaccucggcg ggggaaccuu cgaugugucc gugcugagca uugacgccgg cgucuuugaa      660

gugaaggcua cggcgggcga uacacaucuu gggggagagg acuucgacaa uagacugguu      720

aaccacuuua uggaggaguu ccggcgcaag cauggcaaag aucucucugg gaauaagaga      780

gcccugcggc gccuuagaac cgcuugcgag cgggccaaaa gaacaccguc cagcucuacc      840

caggccaccc uggaaaucga cucccucuuu gagggagugg auuucuauaa gagcauuaca      900

cgcgcucggu ucgaagaacu guguucugac cuguuuagau ccacgcucga gcccgucgaa      960

aaagcccugc gcgaugcgaa acuugacaag gcucagaucc acgauuucgu gcugggcggg     1020

ggacuccaca gccauccuca gggcgccgag guugccgcug gccugcuuca acggcagggg     1080

gccgaacagg agcaccaacc cuga                                            1104


<210>  657
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  657
augagcaagg gccccgccgu ggggaucgac cugggaacca cauacuccug cgucggcguu       60

uuccagcacg ggaaagugga gauuaucgcu aacgaucaag gaaauagaac gaccccuucu      120

uauguggccu uuacagacac cgaacggcuc auuggcgaug cggcuaagaa ccaggucgcc      180

augaauccga caaacaccgu guucgacgcc aaacgccuga ucgggagacg guuugaugac      240

gcuguugugc agagcgauau gaagcauugg cccuucaugg ucgugaauga cgccggacgc      300

ccuaaaguuc agguggagua caagggcgaa acaaaguccu uuuaucccga ggaagucucu      360

agcauggugc uuaccaaaau gaaggagauu gcugaggccu accugggcaa aacggugacc      420

aacgcggucg uuacagugcc ugccuauuuc aaugauuccc aaagacaggc uaccaaggac      480

gccgggacaa ucgcuggacu caacgugcug cggaucauua augaacccac cgccgcggcc      540

aucgcuuacg gccuugauaa aaaggucggg gccgagcgca acgugcugau uuuugaccuc      600

ggaggcggga cguucgaugu uucuauccug acaauugaag acggaaucuu ugaggugaag      660

ucuaccgcug gcgacacaca ccugggcggg gaggauuucg acaauagaau ggucaaccau      720

uuuauugccg aauuuaaacg gaagcacaaa aaggauaucu ccgagaauaa acgcgccgug      780

agacggcucc gcaccgcuug ugaaagagcg aagcggaccc ugagcagcuc cacacaggcc      840

agcaucgaga uugacucucu uuaugaagga aucgauuuuu acacguccau uacccgcgcu      900

agauucgagg agcugaacgc cgaccucuuc cggggcacac uggauccugu ugaaaaagcc      960

cuuagagacg cuaagcugga uaagagccag auccaugaca uugugcucgu cgggggaucu     1020

acccgcaucc cgaaaaucca aaagcugcug caggauuucu ucaauggcaa agagcucaac     1080

aaguccauua accccgacga agccguggcg uacggggcug ccguccaggc cgcuauccug     1140

agcggagaca aauccgagaa ugugcaggau cuucugcucc uggacguuac accucuuucu     1200

cugggcauug aaaccgccgg cggggugaug acgguccuca ucaagcggaa cacaaccauu     1260

cccaccaagc aaacacagac cuuuacaacg uauagcgaua aucagccugg agugcugauc     1320

caaguuuacg agggcgagag agcuaugacc aaagacaaca aucugcucgg gaaguucgaa     1380

cugacaggaa ucccgcccgc cccucgcggc gugccccaga uugaggucac cuuugauauc     1440

gacgcgaacg ggauucuuaa uguguccgcc guggauaaaa gcacaggcaa ggaaaacaaa     1500

aucaccauua cgaaugacaa gggacggcug ucuaaggagg auaucgaaag aaugguucag     1560

gaggcugaga aauauaaggc cgaagacgag aaacagcgcg auaaggucuc cagcaaaaac     1620

ucucucgaaa gcuacgcuuu caauaugaag gccaccgugg aggacgagaa gcugcaaggc     1680

aaaauuaacg augaagacaa gcagaaaauc cuugacaagu gcaaugagau cauuaacugg     1740

cuggauaaaa aucagacagc ggaaaaggag gaauuugagc accagcaaaa agagcucgaa     1800

aaggugugua acccuaucau uaccaagcug uaucaguccg ccgggggaau gcccggcggg     1860

augcccggag gcuucccugg gggcggagcu ccgcccucug gcggggccag cuccggaccu     1920

acaaucgagg aagucgacug a                                               1941


<210>  658
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  658
augaucagcg ccuccagagc ugccgcggcu cggcuggugg gcgccgccgc uucucgcggg       60

cccaccgccg cuagacacca ggacagcugg aacggacucu cccaugaggc cuuccggcug      120

gucucucgca gagauuacgc gagcgaagcc auuaagggcg cuguuguggg gaucgaccuu      180

ggaacaacga auagcugcgu ggccgucaug gagggcaaac aagcuaaggu gcuggaaaac      240

gccgaggggg cgcggaccac accuucuguu guggccuuua ccgcugaugg agaacgccuc      300

gucggcaugc cggccaaaag acaggcugug acaaauccca acaauaccuu cuaugccaca      360

aagcggcuga uuggccgcag auacgacgau ccugagguuc agaaagacau caagaacgug      420

cccuuuaaga uuguccgggc cagcaauggg gaugcuuggg uggaggcgca cggaaaacuu      480

uauuccccua gccagaucgg cgccuucgug cugaugaaga ugaaagaaac cgcugagaac      540

uaccucgggc auacggccaa gaaugccguc aucaccguuc ccgcuuauuu uaacgacucu      600

caacgccagg ccacaaaaga ugcgggacag auuuccggcc ugaaugugcu gagagugauc      660

aacgaaccua ccgcugccgc ccucgcuuac gggcuggaca agagcgagga uaaggucauu      720

gccguguaug accuuggagg cggcacauuc gauaucucua uucuggagau ccagaaaggg      780

guuuuugaag ugaaguccac caauggagac acguuccucg gcggggagga cuuugaucaa      840

gcucugcuuc ggcacauugu caaagaguuc aagcgcgaaa caggagugga ccugaccaaa      900

gauaacaugg cccuccagag aguucgggaa gcggccgaga aggcuaaaug ugagcugucc      960

ucuuccgugc agacagacau caaucugccg uaccucacca uggauagcuc cggccccaag     1020

caucugaaca ugaaacuuac cagagcccag uuugaaggga ucgucacaga ccugauucgc     1080

cggacgaucg cuccuugcca aaaggccaug caggaugcgg aggugucuaa gagcgacauu     1140

ggagaaguca uccucguggg cggcaugacc agaaugccca aaguucagca aacagugcag     1200

gaucuguucg ggcgcgcccc uuccaaggcu gucaaccccg acgaggccgu ggcuauugga     1260

gccgccaucc agggcggggu ucuugcugga gaugugaccg acguccugcu ccuggacgug     1320

acaccgcuga gccucggcau cgaaacccug ggcggcgugu uuacgaaacu uauuaaucgg     1380

aacacaacca ucccuaccaa gaagucucag guuuucucca cagcggccga uggacaaacc     1440

caggucgaga uuaaagugug ucagggcgag agagaaaugg cuggggacaa uaagcugcuc     1500

ggacaguuca cacugaucgg cauucccccu gcuccccgcg gggugcccca aaucgagguc     1560

acguuugaua ucgacgccaa cggaauugug cacguuagcg ccaaagauaa gggcaccggg     1620

cgggaacagc agaucgugau ucagucuagc ggcggacuuu ccaaagacga uaucgagaau     1680

auggucaaga acgccgaaaa guacgcggag gaggacagac gcaaaaagga acggguggag     1740

gcuguuaaua uggccgaagg cauuauccac gauacagaga ccaaaaugga ggaguucaag     1800

gaccaacugc cugccgauga augcaacaaa cucaaggaag agauuucuaa gaugagagaa     1860

cugcuggcuc gcaaagacag cgagacaggg gagaauaucc ggcaggccgc guccagccuc     1920

cagcaggcuu cucugaaacu uuuugaaaug gccuauaaga agauggccuc cgagagagaa     1980

ggaagcgggu cuuccgggac cggagagcaa aaagaagauc agaaggagga gaaacaguga     2040


<210>  659
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  659
auggccgaca aggaggcugg cgggagcgau ggacccagag aaaccgcccc uacauccgcg       60

uacucuagcc cggcucgguc ccugggcgac acggggauca caccccucuc uccuagccac      120

auugugaacg auaccgacuc caaugucucu gagcagcaga gcuuccuggu ugugguggcc      180

gucgauuuug gaaccacauc cagcggcuau gccuacucuu ucaccaaaga acccgagugc      240

auccauguga ugcgcagaug ggaaggggga gacccuggcg uuuccaacca aaagacaccc      300

accacgauuc uucugacccc ugagcggaaa uuucacagcu ucggcuaugc ugcccgcgau      360

uuuuaccaug accucgaucc gaaugaggcu aagcaguggc uguaucuuga aaaauucaag      420

augaagcugc acacaaccgg ggaccucaca auggauaccg accugacggc cgcgaacggc      480

aaaaagguga aagcccugga gaucuuugcu uacgcccucc aguauuucaa ggaacaagcu      540

cugaaagagc uuucugauca ggccggaucc gaguuugaaa auagcgacgu cagaugggug      600

auuacaguuc ccgcgaucug gaagcagccu gccaagcagu ucaugcggca agcugccuac      660

caggcugggc uggccucucc cgagaacucc gaacagcuca ucauugcccu ggagccugaa      720

gcugcgagca ucuacugucg caaacuuaga cugcaucaga ugauugagcu cuccucuaag      780

gccgcuguga auggauauag cggcuccgac accgucgggg ccggauuuac acaagccaaa      840

gagcacaucc ggcgcaacag acagagccgg accuuccugg uggaaaaugu gauuggcgag      900

aucuggucug aacuggagga aggcgauaag uacgucguug uggacuccgg gggaggcacc      960

guggaucuca caguccacca gauucgccug cccgaggggc aucuuaaaga gcuguauaag     1020

gcuacgggag gcccguacgg gagccucgga guggacuaug aauuugagaa acugcuuuac     1080

aagaucuucg gcgaagauuu caucgagcaa uuuaagauua aaagaccugc cgcguggguu     1140

gaccugauga ucgcuuucga aucucggaag cgcgccgccg cucccgauag aaccaacccu     1200

cucaauauua cacugcccuu uagcuucauc gacuauuaca aaaaguuucg gggccacucc     1260

guggagcaug cccugagaaa aucuaacguc gauuucguga aguggagcuc ccaggggaug     1320

cuccgcauga gccccgacgc uaugaaugcc cuguuuaagc cuaccauuga uucuaucauc     1380

gagcaccuuc gggaccuguu ccagaaaccg gaaguuucca cagugaaguu ucucuuccug     1440

gucggaggcu uugcggaggc uccccuucug cagcaagccg ugcaggccgc uuucggggac     1500

cagugcagaa uuaucauucc ucaggauguc ggacucacca uccugaaagg cgccgugcug     1560

uuugggcucg accccgcggu uauuaaggug cgccggagcc cucugacgua cggcgucgga     1620

gugcuuaaca gauauguuga aggcaaacau cccccggaga agcugcucgu gaaggauggg     1680

acacgcuggu guaccgacgu cuucgauaaa uucaucucug ccgaccaauc cguggcucug     1740

ggagagcugg ugaagcggag cuacaccccu gccaaacccu cccagcuugu uaucgucauu     1800

aauaucuauu cuagcgaaca cgauaacgug uccuuuauua cagacccugg cgugaagaaa     1860

ugcgggaccc ucagacugga ucugacagga acgucuggca ccgcuguccc cgcccgccgg     1920

gagauccaga cacucaugca guucggggac accgaaauua aggccacagc uaucgauauu     1980

gcgaccagca aguccgugaa aguuggcauc gacuuucuga acuacuga                  2028


<210>  660
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  660
augcuggccg ugcccgagau gggccuccag gggcuguaca ucggaagcuc cccugaaaga       60

ucuccggucc ccagcccucc cggcuccccu cggacccaag agucuugcgg gauugcuccc      120

cuuacaccua gccagucccc gaagcccgaa guucgcgccc cucagcaggc gucuuucagc      180

gugguggucg cuaucgacuu uggaacgacc uccagcggcu augccuucuc uuuugccucc      240

gaucccgagg cuauucacau gaugagaaaa ugggaagggg gagacccugg cguggcccau      300

caaaagacac ccaccugucu gcuccugaca ccggagggcg cuuuccacag cuuuggguac      360

accgcccggg auuauuacca ugaccuugau ccugaggaag cgcgcgacug gcuguauuuc      420

gagaaauuua agaugaaaau ccacucugcc acagaucuca cccugaagac gcagcuggaa      480

gcuguuaacg gaaagaccau gcccgcccuc gagguguucg cucaugcccu gagauuuuuc      540

cgggagcacg cgcuucagga acugcgcgag caguccccua gccuccccga aaaagacaca      600

gucagauggg ugcugaccgu ucccgccauu uggaagcaac cugcuaaaca guuuaugcgg      660

gaggccgcuu accuugccgg ccuggugucu cgcgaaaaug ccgagcagcu ccugaucgcu      720

cuggagccgg aagcggccuc cgucuauugc agaaagcucc ggcugcacca gcuucuggau      780

cucagcgggc gcgcucccgg aggcgggaga cugggagagc ggcgcuccau cgacucuagc      840

uucagacaag cccgggaaca gcuuagacgc ucccggcaua gcagaacauu ucugguggag      900

ucuggcgugg gcgaacucug ggccgagaug caggcugggg aucgcuacgu cguugccgac      960

uguggaggcg ggaccgugga ucugacggug caccaacugg agcagccuca uggaacacuc     1020

aaagaacugu acaaggcguc cggcgggccc uauggagcug ucggcgugga ccuugccuuc     1080

gagcagcugc ucugccggau uuucggcgaa gacuuuaucg ccaccuucaa gagacagcgc     1140

ccugcugccu ggguugaucu gacaauugcu uuugaggccc ggaaaagaac cgcggggccc     1200

caccgcgccg gagcucuuaa caucagccug ccguucucuu uuauugacuu cuaccggaag     1260

caaagaggcc acaaugugga aaccgcccuc cgccggagcu ccgucaacuu ugugaaaugg     1320

ucuagccagg ggaugcugag aauguccugu gaggcuauga augagcuguu ccagccuaca     1380

guuagcggaa ucauucagca uaucgaagcc cuccuggcgc ggcccgaggu gcaaggcguc     1440

aaacuucugu uucucgucgg gggcuucgcc gaaucugcug ugcugcagca cgccgugcag     1500

gcugcccugg gagcccgcgg ccuuagaguu guggucccuc augauguggg gcucacgauc     1560

cugaagggag cuguucuguu uggccaggcg cccggggugg uccgggugag acgcuccccu     1620

cucaccuaug gagugggcgu ucugaaccgg uucguccccg ggagacaccc gccugagaaa     1680

cuucuggugc gcgacggcag acgguggugc acagaugugu uugagcgcuu cgucgccgcu     1740

gaacaaagcg uggcccucgg agaggaaguu agacggucuu acugucccgc ccgccccggc     1800

cagagacggg ugcugauuaa ucuguauugc ugugcugccg aggacgcgcg cuucaucacc     1860

gauccugggg ucagaaagug cggagcucuu ucccucgaac uggagccggc cgacuguggc     1920

caggauacag ccggggcucc cccuggacgg cgcgagauua gagccgcgau gcaguuuggc     1980

gacaccgaaa ucaaggugac ggcuguugau gugagcacaa accgguccgu cagagccucu     2040

auugacuucc ugagcaauug a                                               2061


<210>  661
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  661
auggccagag agaugaccau ccugggcagc gcugugcuca cacugcuucu ggccggguac       60

cucgcgcagc aauaucugcc ccuuccuacg ccgaagguca uuggaaucga ccugggcacc      120

acauacugcu ccguuggggu guucuuuccc ggaaccggca aagugaaggu cauuccugau      180

gaaaacgggc acaucucuau ucccagcaug guguccuuca cagacaauga uguuuaugug      240

ggauacgagu cugucgaacu cgcugacagc aacccucaga auaccaucua ugaugccaaa      300

cgguuuaucg gcaagauuuu cacagccgag gaacuggagg cugagaucgg ccgcuacccc      360

uuuaaagugc ugaacaagaa ugggaugguu gaguucuccg ugaccucuaa cgaaacgauu      420

accgucagcc cugaauaugu gggauccaga cuccugcuua agcugaaaga gauggccgag      480

gcuuaccucg gcaugccggu ggccaaugcg gucaucagcg uucccgccga auuugaccug      540

aagcagcgga acucuacaau ugaggcugcc aaucuugcug ggcugaaaau ccuccgcgug      600

auuaacgaac cuaccgccgc ggccauggcu uacggacugc auaaggccga uguguuccac      660

guccugguga ucgaccucgg cgggggaaca cuggauguuu cccuucugaa uaaacagggc      720

ggcauguuuc ucaccagagc uaugagcggg aacaauaagc ugggaggcca agacuucaac      780

cagcggcuuc ugcaguaucu cuacaagcag aucuaucaaa cguacggguu ugugcccucu      840

cgcaaagagg aaauucauag acugcggcag gccgucgaga uggugaagcu gaaucucaca      900

cugcaccagu ccgcccagcu uagcguucug cucaccgugg aggaacaaga ucgcaaagag      960

ccucauucuu ccgacacaga acugcccaag gauaaacuua gcuccgcuga cgaccacaga     1020

gucaacucug gauucggccg ggggcugagc gauaagaaau ccggagagag ccaggugcuc     1080

uuugaaaccg agaucucucg caagcuguuc gacacccuga acgaggaucu cuuccagaag     1140

auucuggucc cgauccaaca ggugcuuaaa gaaggccacc uggagaagac agaaauugac     1200

gagguugugc ucgucggcgg guccacgaga aucccucgga uccgccaggu gauucaggaa     1260

uuuuucggaa aagaucccaa uaccagcguu gacccugauc uggcgguggu cacaggcgug     1320

gccauccaag cugggauuga cggaggcucu uggccccuuc aggugagcgc ccuggagauc     1380

cccaacaagc aucuccagaa aaccaauuuu aacuga                               1416


<210>  662
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  662
auggccgcua ucggcgucca ccuggggugc accagcgccu gugucgcggu uuacaaggac       60

ggcagagcug gagugguggc caacgaugcc ggggaccggg ucacacccgc ugugguugcc      120

uauuccgaga augaagagau ugugggacuc gcugccaaac agucucgcau cagaaacauu      180

agcaauacgg ucaugaaggu gaaacaaauc cugggccggu ccucuagcga uccucaggcg      240

cagaaguaca uugccgaauc caaaugccuu guuaucgaga agaacgggaa gcugcgcuau      300

gaaaucgaca ccggagagga gacaaaauuc gugaauccgg aagaugucgc uagacucauc      360

uuuucuaaga ugaaagagac cgcccauagc gugcugggcu ccgacgcuaa cgaugugguc      420

auuacaguuc ccuucgacuu uggcgaaaag cagaaaaaug cccuugggga ggcggcccgg      480

gcugccggau ucaacgugcu gcgccucauu cacgagccua gcgcugcccu gcuggccuac      540

ggcaucgggc aagauucucc caccggaaag uccaauauuc ucguguuuaa gcugggcggg      600

acaagccuuu cucuguccgu cauggaagug aacagcggaa ucuauagagu ucucucuacc      660

aauacggacg auaacauugg cggcgcucau uucaccgaga cacuggcgca guaccuugcc      720

uccgaauuuc agcggagcuu caaacacgac gugcgcggga augcuagagc caugaugaag      780

cugaccaacu ccgccgaggu cgcuaaacau ucucucagca cacugggauc cgccaauugu      840

uuucuggaua gccucuauga aggccaggac uucgacugca acgugucucg ggcgcgcuuu      900

gagcugcuuu guuccccucu guucaacaag ugcaucgagg cuaucagagg gcuccuggau      960

caaaauggau uuaccgccga cgauauuaac aaaguugugc uuuguggcgg gagcucucgg     1020

auccccaagc ugcagcagcu cauuaaagac cuguucccug ccgucgaacu gcucaauagc     1080

aucccgcccg augaggugau uccuaucgga gcugccaucg aagcuggcau ucugaucggc     1140

aaggagaacc uucuggucga agacucccuc augauugagu gcucugcccg cgauauccug     1200

gugaaggggg uugacgagag cggagcgucc agauucacgg ugcuuuuucc cagcggcaca     1260

ccucugcccg cccggagaca gcacacccuc caagcuccgg ggucuauuuc cagcgucugu     1320

cuggaacugu acgagucuga uggcaaaaau uccgccaagg aagagacaaa auucgcucag     1380

gugguucucc aggaccugga uaagaaagaa aacggacuuc gcgacauccu ggccgugcuc     1440

accaugaagc gggacgggag ccugcacgug accugcacag aucaagagac gggcaagugu     1500

gaggcgaucu ccauugaaau cgccucuuga                                      1530


<210>  663
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  663
augagcgugg ucggccugga cguugggucc cagucuugcu acaucgccgu ggcuagagcc       60

ggaggcauug agaccaucgc gaacgaauuu agcgaucggu guacacccuc cgugauuucu      120

uuugggagca agaaucgcac gaucggaguc gcugccaaaa accaacagau uacccacgcc      180

aauaacacag uguccaauuu caagagauuu cauggccggg cuuucaacga cccuuuuauc      240

cagaaagaga aggaaaaucu cucuuaugau cugguuccgc uuaaaaacgg gggagugggc      300

aucaagguca uguacauggg cgaggaacac cuguucagcg uggagcagau uaccgccaug      360

cuccugacaa aacuuaaaga gaccgcugaa aauucccuga agaaacccgu uacagacugc      420

gugaucagcg ucccuucuuu cuucaccgau gccgagcgca gauccgugcu cgacgcggcc      480

caaauugugg ggcugaacug ucugcggcuc augaaugaua ugacggcugu cgcccugaac      540

uauggaaucu acaagcagga ccuucccagc cuggaugaaa aaccucgcau uguuguguuu      600

guggacaugg gccauucugc uuuccagguc uccgccugcg cguuuaauaa ggggaagcuc      660

aaagugcugg gaaccgccuu cgaucccuuu cuuggcggga agaacuucga cgagaaacug      720

guugagcacu ucugugcuga auuuaagaca aaauauaagc ucgaugccaa aagcaagauc      780

agagcucugc ugcggcucua ccaggagugc gaaaagcuga aaaagcugau gucuuccaau      840

agcaccgacc uuccucucaa cauugagugu uucaugaacg acaaagaugu guccggaaag      900

augaaucgcu cucaauuuga ggaacugugc gccgagcuuc ugcagaaaau cgaagucccg      960

cucuauagcc ugcuggagca gacacaucuc aagguggaag acguuuccgc cguggagauc     1020

gucggcggcg cuacccggau ucccgcggug aaggaaagaa ucgccaaauu cuuugggaag     1080

gauauuagca cgacacugaa cgcugacgag gccgucgccc gcggaugugc ccuucagugc     1140

gcuauccugu cuccugcguu caaagugaga gaguuuuccg uuaccgaugc ugugcccuuc     1200

ccuauuagcc ucaucuggaa ucacgacucu gaagauacag agggcgucca cgaaguguuu     1260

agccggaacc augccgcccc cuucuccaag guucugaccu uucuucgcag agggccguuc     1320

gagcuggagg cuuuuuacuc ugacccucaa ggagugcccu acccugaagc caaaaucggc     1380

cgguucgucg ugcagaaugu gagcgcucag aaggaugggg agaaguccag aguuaaaguc     1440

aaggugcgcg ugaacaccca cggaauuuuc acaaucagca cggccucuau ggucgaaaaa     1500

gugcccaccg aggaaaauga gauguccagc gaggcggaca uggaaugucu caaccaacgg     1560

cccccugaga auccggauac agacaagaac guucagcagg acaauucuga agccggcacc     1620

cagccccaag ugcagacaga ugcucagcag accucccaaa gcccucccuc cccugagcug     1680

acgucugaag agaacaaaau ucccgacgcc gauaaggcua augagaagaa agucgaccag     1740

ccgccugaag ccaagaaacc caagaucaaa gugguuaacg uggagcugcc uauugaagcg     1800

aaucucgucu ggcagcuggg caaggaucuu cugaacaugu auaucgagac agaagggaaa     1860

augaucaugc aggacaagcu cgagaaggag agaaacgaug ccaaaaaugc uguggaagag     1920

uacguuuaug aauuucgcga caagcugugc ggacccuacg agaaauucau uugcgaacaa     1980

gaucaucaga acuuucugcg gcuucucacc gagaccgagg acuggcugua ugaagagggc     2040

gaagaucagg ccaagcaggc uuacguggac aaacuggagg agcucaugaa gaucgggaca     2100

ccugucaagg ugagauucca agaagccgag gaacgcccca aaauguuuga ggaacuggga     2160

cagcggcuuc agcacuaugc caagauugcu gcggauuuca gaaauaaaga cgagaaguac     2220

aaccacaucg acgagagcga aaugaaaaag guggagaagu ccgucaauga aguuauggag     2280

uggaugaaca augugaugaa cgcccaagcu aaaaagucuc uggaucagga cccggugguc     2340

cgcgcccagg aaauuaaaac caagaucaaa gagcucaaua acacauguga gccugugguu     2400

acgcagccca agcccaagau ugaaagcccu aaacuggagc ggaccccgaa uggccccaac     2460

aucgauaaga aagaagagga ccuggaagau aagaauaacu uuggggccga gccuccccau     2520

caaaauggcg agugcuaccc uaacgaaaag aacuccguga auauggaccu ugauuga        2577


<210>  664
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  664
auggccgaca aggugagacg gcagcgcccc agacggcgcg ucugcugggc ucugguugcc       60

gugcuccugg cggaucuucu ggcucucagc gacacccugg ccgugauguc cgucgaucuu      120

ggcucugaga gcaugaaagu ggccaucguu aagccugggg ugccgaugga aaucguccug      180

aacaaagagu ccagacggaa gacacccgug aucguuacgc ucaaagaaaa ugagcgcuuc      240

uuuggagacu cugcugccag cauggcuauu aagaacccua aggccacccu gagauacuuc      300

caacaucugc ucggcaaaca ggcggauaau ccccacgugg cccuguauca ggcucgguuu      360

ccugaacacg agcuuacauu cgacccccag cgccaaaccg uccauuuuca gaucuccucu      420

cagcugcagu ucagcccuga ggaagugcuc gggauggugc ugaacuacuc cagaagccuu      480

gccgaggauu uugcugaaca accgauuaag gacgccguca ucacaguucc cguguucuuu      540

aaucaggcgg agcggcgcgc cgugcugcag gcugccagaa uggcuggacu caaaguccug      600

cagcugauca acgauaauac cgccacagcc cucucuuaug gcguguuccg gcgcaaggac      660

auuaacacca cggcucaaaa uaucauguuu uacgauaugg gguccggaag caccguuugu      720

acaauuguga ccuaucagau ggucaaaaca aaggaggcgg gcaugcagcc ucaacugcag      780

aucagaggcg ugggguucga ccggacccuu ggaggccugg aaauggagcu cagacugcgc      840

gaacggcuug ccgggcuguu uaacgagcag agaaagggac agcgcgcuaa agauguucgg      900

gaaaauccca gagccauggc caagcuccug cgcgaggcua accggcugaa aacggugcuc      960

ucugccaaug cggaccacau ggcucaaauu gagggccuga uggacgaugu cgacuucaag     1020

gccaaaguga caagagucga guucgaggaa cuuugcgccg aucuguuuga gcgcgugccu     1080

gggcccguuc agcaggcucu ccaguccgcc gaaaugagcc uggacgagau cgagcaagug     1140

auucuugucg gaggcgcuac ccgggugccg agaguucagg aagugcugcu caaggccguc     1200

ggcaaagagg aacuggggaa gaacaucaau gcggaugagg ccgcugccau gggagcugug     1260

uaccaggccg cggcccuguc uaaggcuuuc aaagugaagc cuuuuguugu ccgcgacgcc     1320

gugguguauc ccauccucgu cgaguucaca cgggaggugg aggaagaacc uggcauucau     1380

ucccugaaac acaacaagag aguucuuuuu agccggaugg ggcccuaccc ccagcgcaaa     1440

gugaucaccu ucaacagaua cucccacgau uuuaauuucc auauuaacua uggagaccug     1500

ggcuuucucg ggccugaaga ucugcggguc uucggaucuc aaaaucugac cacagugaag     1560

cucaagggcg uuggcgacag cuuuaaaaag uacccggauu augaguccaa agggaucaag     1620

gcucacuuca accucgacga gagcggagug cugucucugg acagagucga auccguguuu     1680

gagacgcucg uugaagauag cgccgaggaa gagucuaccc ugacaaaacu uggcaauacc     1740

auuagcuccc uguucggggg aggcacaacc cccgacgcca aggagaacgg gacggauaca     1800

gugcaggaag aggaagaguc uccugcugaa ggcagcaagg acgagcccgg agagcagguc     1860

gaacucaaag aggaagcgga ggccccugug gaagauggcu cccagccccc gccucccgag     1920

ccuaaggggg acgcuacccc cgagggagaa aaagccaccg agaaggaaaa uggcgauaaa     1980

agcgaggccc aaaagccuuc ugagaaggcu gaagccgggc ccgagggagu ggcgccggcu     2040

ccugaaggcg agaaaaagca gaaacccgcc cgcaagcgga gaauggucga agagaucggg     2100

guugagcugg uggugcugga ccuucccgau cucccugaag acaaacuggc ccaguccguc     2160

caaaagcugc aggaucucac acugcgcgac cuugagaaac aggaaagaga gaaggcugcc     2220

aacagccugg aagcguucau cuuugagacc caggauaagc ucuaccaacc ggaguaucag     2280

gaagugucua cagaggaaca gcgggaggaa auuuccggca aacugagcgc ugccuccacg     2340

uggcuggagg acgagggagu uggcgccacc acagugaugc uuaaggaaaa acucgcugag     2400

cugcgcaagc ugugucaggg gcuuuucuuu agagucgaag aacggaaaaa guggcccgag     2460

cgccugucug cccuugacaa ucugcucaac cauagcucca uguuccugaa gggagcuaga     2520

cugaucccug aaauggauca aauuuuuacc gagguggaaa ugacaacccu ugagaaaguu     2580

aucaaugaaa cgugggccug gaagaacgcg acccucgccg agcaggcuaa acugcccgcc     2640

acagagaagc cugugcugcu cucuaaagac auugaagcua agaugauggc ccuggaucgg     2700

gagguccagu accuucugaa uaaggccaaa uucaccaagc cccgcccuag acccaaagac     2760

aagaacggca cacgggcuga accgccucuc aaugcgagcg ccuccgauca gggggagaaa     2820

gugauucccc cugcuggaca aaccgaagac gccgagccca ucagcgagcc ggaaaagguu     2880

gagacgggcu cugaaccugg ggauacagag ccccuggaac ugggcggacc uggcgccgag     2940

cccgagcaga aggaacaguc caccgggcaa aaacgccccc uuaagaacga cgagcuguga     3000


<210>  665
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  665
augcccgagg aaacccagac acaagaccag cccauggagg aagaggaagu ggagacguuc       60

gccuuucagg cugagaucgc ccagcugaug agccucauua ucaacaccuu cuacuccaau      120

aaggaaauuu uucugagaga gcuuaucucu aacagcuccg augcgcugga caaaauucgg      180

uaugaaucuc ucacagaucc gagcaagcug gacuccggca aagagcuuca caucaaucug      240

auccccaaca agcaagaucg cacccucaca auugucgaca ccgggaucgg aaugacaaaa      300

gcugaucuga uuaauaaccu gggcaccauc gccaagucug ggacgaaggc cuucauggag      360

gcucuccagg ccggagcuga cauuagcaug aucggccagu uugggguugg auucuacucc      420

gccuaucugg uggcggaaaa agugaccguc auuacaaagc auaaugauga cgagcaguac      480

gccugggaaa gcucugcugg cggcuccuuu accgugagaa cagauaccgg ggagccuaug      540

ggacggggca cgaaaguuau ccuucaccug aaggaagacc aaacagagua ucucgaggaa      600

cgcagaauca aagagauugu gaagaagcau agccaguuca ucggguaccc cauuacccug      660

uuugucgaaa aagagcggga uaaggaagug ucugacgacg aggccgagga aaaagaggau      720

aaggaagagg aaaaagagaa ggaggaaaaa gaguccgaag acaagccuga gaucgaggau      780

guuggaagcg acgaagagga agagaagaaa gauggcgaca agaaaaagaa aaagaagauu      840

aaagaaaagu auaucgauca ggaggagcuu aacaaaacaa agcccaucug gacccgcaau      900

ccugacgaua uuaccaacga agaguacggg gaguucuaca aaucucugac aaaugacugg      960

gaggaucacc ucgcugugaa gcauuuuucc gucgaaggac agcuggaguu cagagcccug     1020

cucuuugugc cgcggcgcgc gcccuucgac cuguucgaga acagaaagaa aaagaauaac     1080

aucaaacuuu augugcggcg cgucuuuauu auggacaauu gcgaagaacu gaucccugaa     1140

uaccucaacu ucauuagagg cguuguggau agcgaggacc ugccccuuaa caucucccgg     1200

gaaaugcugc aacagucuaa gauccucaaa gugauucgca agaaucuggu caagaaaugu     1260

cuggagcucu uuacggagcu ggccgaagau aaggagaacu auaaaaaguu cuacgaacag     1320

uuuagcaaaa auaucaaacu uggcauucac gaggacuccc aaaacagaaa gaagcugagc     1380

gagcuccugc gguauuacac cucugcuucc ggggaugaaa uggugagccu uaaggacuau     1440

ugcacaagaa ugaaagagaa ucagaagcac aucuacuaca uuaccggaga aacaaaagau     1500

cagguugcca acucugcuuu cguggagcgc cugcggaagc auggccucga agucaucuau     1560

augauugagc cuaucgacga guacugugug cagcaacuga aagaauuuga ggggaagacc     1620

cugguuagcg ugacgaagga aggacucgag cugcccgaag augaggagga gaaaaagaaa     1680

caggaagaaa agaaaacaaa guucgagaau cuuugcaaga ucaugaaaga cauucuggaa     1740

aagaaagucg agaagguggu cguguccaac agacucguua ccucuccgug uugcaucgug     1800

accagcacau auggcuggac cgccaauaug gagcgcauua ugaaagccca ggcucugcgg     1860

gauaacucca caauggggua cauggcggcc aagaagcacc uggaaaucaa uccugaccau     1920

agcauuaucg agacgcuuag acagaaagcu gaagccgaua agaacgacaa aucugucaag     1980

gaccucguga uccugcugua ugagaccgcc cuccugucca gcggauuuuc ucuugaggau     2040

ccccaaacac acgcuaaucg cauuuaccgg augaucaaac ugggccucgg cauugacgaa     2100

gaugacccua ccgccgauga cacauccgcg gcuguuaccg aggaaaugcc uccccuggag     2160

ggggaugacg auacgagcag aauggaagag guggacuga                            2199


<210>  666
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  666
auggacagcu ccaagcugga uucuggcaaa gggcuccaca ucaaccuggu gcccaauaag       60

cagaaccaaa cccuuacaau ugucgacacg agaaucggaa ugaccaaaac agaucugauu      120

aauaaccucg gcaccguuac aaagagcggg accaaagccu ucauggaggc ucugcaggcc      180

gacgcggaua ucuccaugau uggacauuuu ggcguggggu ucuacucugc uuaucuugug      240

gccaagaagg ucacagugau cagcaaacac aauaacgacg aacaguacac cugggagucc      300

ucugccggag gcagcuuuac gguucggacc gaugaauga                             339


<210>  667
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  667
augcccgagg aagugcacca uggcgaggaa gaggucgaaa ccuucgccuu ucaggcugag       60

aucgcccaac ugaugagccu cauuaucaac acauucuacu ccaauaagga gauuuuucug      120

agagaacuua ucucuaacgc gagcgacgcu cuggauaaaa uucgguauga gucccucacg      180

gacccuucua agcuggauag cgggaaagaa cuuaagaucg acaucauucc gaauccccag      240

gagcgcaccc ugacacucgu ugauaccgga aucggcauga caaaagccga ccugauuaac      300

aaucugggga ccaucgccaa guccggaaca aaggcuuuca uggaggcccu ccaggcuggc      360

gccgauauuu cuaugaucgg gcaguuugga gugggcuucu acagcgcgua ucugguggcc      420

gaaaaagucg ugguuauuac caagcacaac gacgaugagc aauacgcuug ggaauccagc      480

gccggcgggu cuuuuacggu gagagcugac cauggagagc cuaucggccg ggggaccaaa      540

gucauccuuc accugaagga agaucagaca gaguaucucg aggaacgcag agugaaagag      600

guugugaaga agcauuccca guucauugga uaccccauca cccuguaucu ugaaaaagag      660

cgggaaaagg agauuagcga cgaugaggcc gaagaggaaa aaggcgagaa ggaagaggag      720

gacaaagacg augaagagaa gccuaaaauc gaagacgucg ggucugauga ggaggacgau      780

uccggaaagg acaagaaaaa gaaaacaaag aaaauuaagg aaaaguacau cgaucaggag      840

gaacugaaua aaaccaagcc caucuggacg cgcaacccug acgauauuac acaagaggaa      900

uacggcgagu uuuauaaaag ccucaccaau gacugggagg aucaccuggc ggugaagcac      960

uucucugugg aaggccagcu ggaguuuaga gcccuccugu ucaucccgcg gcgcgcuccc     1020

uuugaccuuu ucgaaaacaa aaagaagaaa aauaacauua agcuguacgu cagacggguu     1080

uucaucaugg acuccugcga ugagcucauu ccugaauauc ugaauuuuau ccgcggggug     1140

guggacagcg aggaucuucc ccugaacauc uccagagaga ugcuccagca gucuaaaauu     1200

cugaagguca uccggaaaaa uauugugaag aagugucugg aacucuucag cgagcuggcc     1260

gaagacaaag agaacuacaa gaaauuuuau gaggcuuucu ccaagaaccu uaaacuggga     1320

auccaugagg auagcacaaa ucgcagacgg cucucugagc ugcuuagaua ccacaccucc     1380

caaagcggcg acgaaaugac cucucugagc gaguauguuu cccgcaugaa ggaaacacag     1440

aaaucuauuu acuacaucac gggggagagc aaggaacagg uggccaacuc cgccuuuguc     1500

gaacggguga gaaagcgcgg auucgagguu guguauauga ccgaaccuau ugaugaguac     1560

ugcguccaac agcucaaaga auuugacggc aagagccugg ugucugucac aaaagagggg     1620

cuggagcucc ccgaagauga ggaagagaag aaaaagaugg aagaguccaa ggcuaaauuc     1680

gagaaucugu guaaacuuau gaaggaaauc cuggacaaga aaguggagaa gguuaccauc     1740

agcaaccggc ucgugucuuc cccgugcugu auugucacaa gcaccuaugg auggacggcg     1800

aauauggaaa gaaucaugaa ggcccaggcu cugcgcgaua acuccacaau gggcuacaug     1860

auggccaaaa agcaucugga gauuaauccu gaccacccca ucguggaaac ccuucggcag     1920

aaagccgagg cugauaagaa cgacaaagcc guuaaggacc ucgugguccu gcuguuugag     1980

accgcgcucc ugucuagcgg cuucucccuu gaagauccuc aaacacacuc uaauagaauu     2040

uaucgcauga ucaagcuggg gcucggaauc gacgaggaug aaguggcugc cgaggagccc     2100

aacgccgcug ugcccgacga aauuccuccg cuggagggcg augaagacgc cagccggaug     2160

gaggaaguug auuga                                                      2175


<210>  668
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  668
augagagccc ugugggugcu cggccugugc uguguccuuc ugaccuucgg gagcguucgg       60

gcugacgaug agguggacgu ggauggaaca gucgaagagg accucggcaa gucccgcgaa      120

gggucuagaa cggaugacga ggugguucag cgggaagagg aggccaucca acuggaugga      180

cuuaacgcga gccagauucg cgaacugaga gagaaauccg aaaaguuugc uuuccaggcc      240

gaggugaauc ggaugaugaa acucaucauu aacucucugu acaagaauaa agagaucuuu      300

cugcgcgaac ucauuagcaa cgccuccgac gcucuggaua agaucagacu uaucucucug      360

accgacgaga augcccucag cggcaacgaa gaacugacag ucaagauuaa augcgauaag      420

gagaaaaauc uucugcacgu gaccgacaca gggguuggaa ugacccggga ggagcucgug      480

aagaaccugg gcacaaucgc uaaauccggc accagcgagu uccugaauaa gaugacggag      540

gcccaggaag augggcaauc uaccuccgag cucauuggac aguuuggcgu cggguucuau      600

agcgcguuuc ugguggccga caaggugauc gucacaucua aacauaacaa ugacacccag      660

cacauuuggg aauccgauag caacgaguuc ucuguuaucg cugacccccg cggaaauaca      720

cuuggcagag ggaccacgau uacacuggug cucaaggagg aagccuccga uuaccuggag      780

cuugacacca ucaaaaaccu ggugaagaaa uauagccagu uuaucaauuu cccuauuuac      840

gucugguccu cuaagacaga aaccguggag gaaccgaugg aggaggaaga ggcugccaaa      900

gaagagaagg aggaaagcga ugacgaggcg gccguugaag aggaagagga ggaaaagaaa      960

cccaagacca aaaaggugga gaaaacaguc ugggauuggg aacucaugaa cgacaucaag     1020

ccuauuuggc aacggcccuc caaggaggug gaagaggaug aguauaaagc cuuuuacaag     1080

agcuucucua aagaauccga cgauccuaug gcuuauaucc auuuuacggc ugagggagaa     1140

guuaccuuca agagcauucu guucgugccc acaucugccc cucgcggccu guuugacgag     1200

uacggcagca aaaaguccga cuacaucaag cucuauguca gacggguguu caucaccgau     1260

gacuuucacg auaugaugcc gaaauaccug aacuucguca aggggguggu ugacucugau     1320

gaccuucccc ugaaugugag ccgcgaaaca cuccagcagc auaaacugcu uaaggucauu     1380

cggaaaaagc uggugagaaa gacccucgau augaucaaaa agauugccga cgauaaauau     1440

aacgacacgu uuuggaagga guucggaaca aauaucaaac ugggcguuau ugaggaucac     1500

uccaacagaa cccgccuggc uaagcuccug cgguuucaga gcucucacca uccuaccgac     1560

aucacauccc uugaucaaua cguggaaaga augaaagaga agcaggacaa gaucuauuuc     1620

auggcgggga gcucucgcaa agaagccgag uccagccccu uugucgagcg gcugcucaag     1680

aaaggauacg aagugauuua ucugaccgag ccuguggacg aauacuguau ccaggcucug     1740

cccgaguucg auggcaagag auuucaaaau guugccaaag aaggggucaa guucgacgag     1800

uccgagaaga caaaagaauc ucgcgaggcc guggaaaagg aguuugaacc gcuucucaac     1860

uggaugaaag auaaggcucu gaaagacaag auugagaagg ccguggucag ccagcggcug     1920

acggaguccc cuugcgcgcu cguggcuucu caguacggau ggagcggcaa uauggaaaga     1980

aucaugaaag cccaggccua ucaaaccggc aaggauauuu ccacaaacua cuaugcuagc     2040

cagaaaaaga ccuucgagau caauccccgc cacccucuga uucgggacau gcuuagacgc     2100

aucaaagaag augaggacga uaagacaguu cuggaccucg ccgugguccu guucgaaacc     2160

gcuacgcugc ggucugggua ccuucucccc gauaccaagg ccuauggaga cagaaucgag     2220

cggaugcugc gccugucccu caacauugau cccgacgcga aaguggagga agaaccugaa     2280

gaggagccgg aagagacagc cgaagacacc acagaggaua ccgaacagga cgaggaugag     2340

gaaauggacg uuggcacgga ugaggaagag gaaacagcua aggagagcac cgccgagaaa     2400

gacgaacugu ga                                                         2412


<210>  669
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  669
auggccagag agcugcgggc ucuccugcuu uggggccgca gacugcggcc ccuccugcgc       60

gccccugcgc uugcugccgu gcccggggga aagccgaucc ugugcccuag acggaccaca      120

gcccagcucg gcccccgcag aaacccugcu uggagccugc aagccgggcg gcuguucucc      180

acgcagaccg cugaagacaa agaggaaccc cuccacucua uuaucagcuc cacagagucu      240

guccagggaa gcaccuccaa gcaugaauuu caggccgaga caaagaagcu gcuugauauu      300

guugcgcgcu cucuguacag cgagaaagaa guguucauca gagagcucau uuccaaugcc      360

agcgacgcuc uggaaaaacu ucggcacaag cuggugucug auggccaagc ccucccugag      420

auggagaucc aucugcagac caacgcugaa aaagggacaa ucaccauuca ggacacggga      480

aucggcauga cccaggagga acuggucucc aaucucggca caauugcccg cagcgggucu      540

aaggcguuuc uggaugcccu ucaaaaccag gcugaggccu ccagcaaaau cauuggacag      600

uucggcgugg gguuuuauuc ugcuuucaug guugccgaca gaguggaagu cuacucccgg      660

agcgccgcuc cgggaucccu gggcuaucag uggcucucug augggagcgg aguguuugag      720

aucgcggagg ccuccggcgu ucgcaccggc acaaagauua ucauccaccu gaaaagcgac      780

uguaaggagu ucucuuccga ggcuagagug cgggaugucg ugaccaagua cagcaauuuu      840

gugucuuucc cccuuuaucu gaacgggaga cgcaugaaua cgcuccaagc cauuuggaug      900

auggacccua aagauguccg ggaauggcag caugaggaau uuuacagaua uguugcccag      960

gcucacgaca agccccgcua cacacugcac uacaaaaccg augccccucu gaacauccgg     1020

agcauuuucu augugcccga caugaagccg uccauguuug acgugucuag agagcucgga     1080

agcuccgucg cgcuguacag ccgcaaagug cuuauccaaa caaaggcuac cgauauucug     1140

ccuaaauggc uccgguucau cagaggcguu guggacucug aggauauccc ccugaaucuu     1200

ucccgcgaac ugcuccagga gagcgcccug auucggaagc ugagagacgu ccuccagcag     1260

cgccugauca aguucuuuau ugaucaaucu aaaaaggacg ccgaaaaaua ugcuaaguuc     1320

uuugaggauu acgggcuuuu caugcgggaa ggaaucguga ccgccacaga gcaggagguu     1380

aaagaagaca uugcuaagcu gcucagauau gaguccagcg cccugccuuc cggccagcug     1440

acgucucuua gcgaauacgc gucccggaug cgcgccggga ccagaaacau cuauuaccuc     1500

ugcgcuccca aucggcaucu ggccgagcac ucucccuacu augaggcuau gaagaaaaag     1560

gauacagaag ugcuguuuug uuucgagcag uuugacgaac ucacccugcu ucaucugaga     1620

gaguucgaua aaaagaaacu caucagcguc gaaacagaca uuguggucga ccacuacaag     1680

gaggagaagu uugaagaucg cuccccugcc gcggagugcc ugagcgaaaa agagaccgaa     1740

gaacugaugg ccuggaugcg gaacgugcuu ggaucuagag uuacgaaugu gaaggucaca     1800

cuccgccugg acacccaccc ggcuauggug accguucugg agaugggcgc cgcuagacau     1860

uuccuccgga ugcaacagcu ggccaaaaca caggaggaac gcgcccagcu ucugcaaccc     1920

acccucgaaa ucaacccuag acacgcucug auuaagaaac ugaaucagcu ucgggcgucc     1980

gagcccggcc ucgcccagcu gcugguggau cagaucuaug aaaacgcuau gauugccgcc     2040

gggcucgucg acgauccucg cgcuauggug ggaagacuga acgagcuucu ggugaaggcc     2100

cucgagcggc auuga                                                      2115


<210>  670
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  670
augggcaaga ucagcucccu gcccacccag cuuuucaaau gcuguuuuug cgacuuccug       60

aaggugaaaa ugcacacaau gucuagcucc caucucuuuu accuggcccu cugucugcuu      120

acguucaccu cuagcgcuac agccgggccu gagacccugu gcggagcgga acucgucgau      180

gcucugcaau uuguuugugg cgacagaggg uucuauuuua acaagccgac aggauacggc      240

uccucuagcc ggcgcgcucc ccagaccggg auuguggaug agugcuguuu cagauccugc      300

gaccugcggc gccucgaaau guauugugcc ccucugaaac ccgccaagag cgccagaucu      360

gugcgggcuc agcgccacac agauaugccu aagacccaga aagaggucca ucuuaagaau      420

gccuccagag gaagcgcggg caacaaaaau uaccggaugu ga                         462


<210>  671
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  671
augggcaucc ccaugggaaa gagcaugcug gugcuccuga ccuuccuugc cuuugcuucc       60

ugcuguauug ccgcguacag accuucugag acacugugcg ggggcgaacu cgucgacacg      120

cugcaguucg uuugugggga ucggggauuu uauuucagcc gcccggcuuc cagagugucu      180

cggcgcagca gaggcaucgu ggaggaaugc uguuuucggu ccugcgaccu ugcccugcuc      240

gagaccuacu gugccacacc cgcuaaaucu gaacgcgaug ucagcacccc ucccacagug      300

cugccugaca acuuccccag auauccuguu gggaaguuuu uccaauacga uaccuggaaa      360

caguccacac agcggcugcg cagaggacuc ccggcccugc uucgggcucg cagaggccac      420

gugcuggcca aggagcucga ggcguuucgg gaagccaaac gccauagacc ccugauugcc      480

cuuccuaccc aggaccccgc ucacggcggg gcuccucccg agauggccag caaucggaag      540

uga                                                                    543


<210>  672
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  672
augaacagcu ucuccaccuc ugccuuuggc cccguggcuu ucagccuggg gcuccugcuu       60

guccugccug ccgcguuucc ggcucccguu ccucccggag aggacuccaa ggauguggcc      120

gccccucaca gacagccccu cacaucuagc gaacggaucg acaaacaaau ucgcuacauc      180

cuggauggca uuuccgcucu uagaaaggag acgugcaaua aaucuaacau gugugaaagc      240

uccaaggagg cccuggcuga aaauaaccuc aaucugccua aaauggccga gaaggacggg      300

ugcuuccaga gcggauuuaa cgaggaaacc ugucugguga agaucauuac aggccuccug      360

gaguucgaag ucuaucuuga guaccugcag aaucgguuug agucuuccga agaacaggcg      420

cgcgccgugc aaaugagcac caaaguucuc auccaguucc ugcagaagaa agcuaagaac      480

cuugaugcca ucacaacccc ggaccccaca accaaugcuu cucugcucac gaaacugcag      540

gcccaaaacc aguggcugca ggauaugacc acacaucuca uucugagauc cuuuaaggag      600

uuccuucaga gcucucugcg ggcgcuccgc caaauguga                             639


<210>  673
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  673
augccccugc ucuggcugag aggcuuccuu cuggccagcu gcuggaucau ugugcggucc       60

ucuccuaccc cggggagcga gggacacucc gcugcccccg acuguccuuc uugcgcgcuc      120

gcugcccugc ccaaggaugu cccuaacagc cagcccgaaa ugguugaggc cgugaaaaag      180

cauauccuua auaugcugca ccucaaaaag cgcccugacg ugacacaacc gguccccaaa      240

gcugcccugc ugaacgcuau uagaaagcuc caugugggca agguugggga aaauggauac      300

guggagaucg aagaugacau uggccggcgc gccgagauga acgagcugau ggaacagacg      360

uccgagauca ucaccuuugc ggaaucuggg acagccagaa aaacccuuca cuucgagauu      420

agcaaggagg gauccgaucu gagcgucgug gaacgggcug agguuuggcu cuuucugaaa      480

gugccuaagg ccaaucgcac aagaaccaaa gucacaaucc ggcuuuucca gcagcaaaag      540

cauccccagg gcucucugga caccggcgaa gaggcugaag agguggggcu caagggagag      600

cgcuccgaac ugcugcucag cgagaaagug gucgaugcca gaaagucuac guggcacguu      660

uuuccugugu ccagcucuau ucagcggcug cuugaccagg gcaaauccag ccuggaugug      720

cgcaucgcgu gugaacaaug ccaggagucc ggggccucuc ucguccugcu uggaaagaaa      780

aagaaaaagg aagaggaggg cgaagggaag aaaaagggag gcggcgaagg gggagcuggc      840

gccgacgagg agaaagaaca gagccacaga cccuuccuga ugcuccaggc ucggcaaucc      900

gaggaucauc cgcaccgcag acggagacgc gggcuggagu gugacggaaa ggugaacauu      960

ugcuguaaaa agcaguuuuu cguuagcuuu aaggauaucg gcuggaauga cuggauuauc     1020

gccccuucug gguaucaugc caacuacugc gaaggagagu gucccuccca caucgcuggc     1080

accagcggcu cuagccuguc cuuccacucu acagugauua aucauuaucg gaugagaggg     1140

cacagcccuu uugcgaaccu caaauccugc ugugucccca ccaagcugcg ccccaugagc     1200

augcuuuacu augacgaugg acagaauauc auuaaaaagg acauccaaaa caugauugug     1260

gaagagugcg gcugcucuug a                                               1281


<210>  674
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  674
auggacggcc ugcccgggag agcccucgga gcugccugcc ugcuucugcu cgcggcuggc       60

uggcuggggc cugaggccug gggaagcccg acacccccuc ccaccccugc cgcucccccu      120

ccgcccccuc ccccuggcuc ccccggggga ucucaggaua cguguaccag cugcggcggc      180

uuccggcgcc cggaggaacu ugggagagug gacggagauu uucuggaagc cgucaagcgg      240

cacauccucu cccgccugca aaugagaggc cggccuaaca uuacacaugc uguucccaaa      300

gccgcgaugg ugaccgcccu gcgcaagcuc cacgcuggga aagugagaga ggacggacgg      360

gucgaaaucc cucaucugga uggccacgcc ucucccgggg cugacggaca ggagcgcgug      420

agcgagauua ucuccuucgc cgaaacagau ggccuugcgu cuagcagagu ucggcuguac      480

uuuuucauuu ccaaugaggg caaccagaau cucuuugugg uccaggccag ccuguggcuu      540

uaucugaagc uccugcccua cgugcuggaa aaagggucuc gcagaaaggu ucgggugaag      600

gucuauuucc aagagcaggg acauggcgac cgcuggaaca ugguggagaa aagaguggau      660

cucaagcggu ccggguggca caccuuuccu cugacagaag cuauccaggc ccuuuucgag      720

agaggagaac gccggcugaa ucucgacguc cagugugaua gcugccaaga gcuggcuguu      780

gugccggugu uugucgaccc cggcgaagag ucucacagac cuuucguggu ugugcaggcc      840

cgccuugggg auucccggca uagaauccgc aaacggggac uggaguguga cggcagaacc      900

aaccucugcu gucgccagca guuuuucauu gacuuucggc ugaucggcug gaaugauugg      960

auuaucgccc ccacggggua cuauggaaac uacugcgaag gcagcugucc ugcuuaucug     1020

gcgggggucc ccggaucugc cuccagcuuc cacaccgcug ugguuaauca auacagaaug     1080

cgcggccuca acccggggac agucaauucc ugcuguauuc cuaccaagcu gucuacaaug     1140

agcaugcuuu acuucgacga ugaguauaac aucgugaaac gggacgugcc caauaugauu     1200

gucgaagagu gcggcugcgc cuga                                            1224


<210>  675
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  675
auggcccuga gagugcuccu gcuuaccgcu cugacacucu gccacggcuu caaccuggac       60

acggagaaug ccaugaccuu ucaggaaaac gcgcgggggu ucggacaaag cgugguucag      120

cuucagggcu cccgcguggu ggucggggcu ccccaggaga ucguggccgc caaucaaaga      180

ggaucucugu accaguguga uuauagcaca ggcuccugcg aaccuauucg gcuccagguu      240

ccgguggagg cugucaacau gucucugggg cugagccucg ccgcuaccac auccccuccu      300

cagcugcuug ccuguggacc caccgugcau caaacaugcu cugaaaauac cuacguuaag      360

ggccuguguu uucucuucgg cagcaaccug cgccagcagc cucagaaauu ucccgaggcg      420

cuuagagggu gcccucaaga ggacuccgau aucgccuucc ugauugacgg aagcggcucu      480

aucauuccgc acgauuuucg gcgcaugaag gaguucgugu ccacggucau ggaacagcuc      540

aaaaagagca aaacccuguu uucucugaug caguauuccg aagaguucag aauccauuuu      600

acauucaagg aguuucaaaa uaaccccaau ccucggagcc ucgugaagcc caucacccag      660

cugcuugggc gcacacacac cgcuacggga auuagaaaag ugguccggga acuguucaac      720

aucacaaaug gcgcccgcaa gaacgcuuuc aaaauucucg uugugaucac cgacggggag      780

aaguuuggag auccucuggg cuacgaagac gugauucccg aggccgauag agaaggcguc      840

auccgguaug ugauuggggu uggagacgcg uuccgcucug agaaauccag acaggagcuu      900

aauacaaucg ccagcaagcc gccucgggau cauguguuuc aggucaacaa uuucgaagcu      960

cugaagacca uccaaaacca gcucagagag aaaauuuuug ccaucgaagg cacccagaca     1020

ggguccucua gcuccuucga gcacgaaaug agccaggagg gauuuucugc ugccauuacg     1080

uccaacggcc cccugcugag caccgugggg ucuuacgacu gggccggagg cguuuuccuc     1140

uauacaagca aggagaaauc caccuuuauc aauaugacac gcguggauuc ugacaugaac     1200

gacgcuuacc ugggcuacgc ggccgcuauu auccuucgga auagagucca aagccuggug     1260

cucggggccc cucgcuauca gcacaucgga cuggucgcca uguuccggca gaacaccggc     1320

augugggaau ccaaugcuaa cgugaagggg acgcagauug gagccuacuu uggcgcgagc     1380

cuuuguucug uugaugugga cuccaauggg agcacagauc ugguccucau cggcgcuccc     1440

cauuauuacg agcaaaccag aggaggccag gugucuguuu gcccccugcc ucgcgggcgg     1500

gccagauggc agugugacgc cgugcuguau ggagaacagg gccaaccgug ggggcgcuuc     1560

ggagcugccc ucaccguccu gggcgaugug aacggggaca aacuuacaga uguggcuauu     1620

ggcgcccccg gagaggaaga caaucggggc gcgguuuacc uguuucacgg gaccuccgga     1680

agcggcaucu ccccuucuca uagccagaga auugccgggu ccaagcucuc uccccgccug     1740

caguauuucg gacaaagccu guccggcggg caggaucuua caauggacgg ccucgucgau     1800

cugacggugg gagcucaggg ccacgugcug cuccugcgga gccagccugu ccuuagagug     1860

aaagccauca uggaguucaa cccccgggag guugcucgca auguguuuga augcaacgac     1920

caagucguga aggggaagga ggccggagaa guuagagugu gucugcacgu ccagaaaucu     1980

acccgggaca gacuccgcga gggccagauc caguccgugg uuacauacga ucuggcgcug     2040

gacagcgggc ggccgcauuc uagagccgug uucaaugaga ccaagaacuc cacacgcaga     2100

caaacccagg uccuuggacu cacgcagacc ugcgaaacac ugaaacugca gcucccuaau     2160

ugcauugagg aucccgugag cccuaucgug cugcggcuua acuuuucucu ggucggcaca     2220

ccccucagcg cuuucgggaa ccugcgcccu guucuggccg aagacgcuca aagacuuuuu     2280

accgcccucu uccccuuuga gaagaauugu ggcaacgaua auauuugcca ggacgaucug     2340

uccaucaccu ucagcuuuau gucucuggac ugucucgugg ugggaggccc gcgggaguuc     2400

aacgucacgg ugacaguucg caaugauggg gaagacuccu acagaaccca ggugacauuu     2460

uucuuuccuc uggaucuuag cuaucggaaa gucuccaccc ugcaaaacca gcgcucucag     2520

agaagcuggc ggcucgccug cgaguccgcu ucuagcaccg aaguguccgg agcgcugaag     2580

ucuacaagcu guuccauuaa ucaccccauc uuccccgaga acagcgaagu uacguucaau     2640

auuaccuuug acguggauuc uaaggccucc cugggcaaca aacuucuccu gaaggcuaau     2700

gucacaagcg agaacaauau gccucgcacc aacaaaacag aguuccagcu ggaacucccg     2760

gugaaguacg ccguuuauau gguggucacc ucucaugggg uguccacgaa auaccugaau     2820

uuuacagcca gcgagaacac cucuagagug augcaacacc aguaucaggu cuccaaccuu     2880

ggacagcgga gccugcccau cucccucguu uuccuggugc cugugagacu gaaucaaacc     2940

gucaucuggg accgccccca ggugacauuu agcgaaaacc uuucuagcac augccauacc     3000

aaggagcggc ugccuuccca cucugacuuc cucgcugaac ugagaaaggc ccccguugug     3060

aauuguagca uugcggucug ccagcgcauc cagugugaua uucccuuuuu cggcauccaa     3120

gaggaauuua acgcuacgcu caaaggcaau cuguccuucg acugguacau uaagaccucu     3180

cacaaccauc uucugaucgu gagcacagcc gagauccucu uuaaugauuc cguuuucacc     3240

cugcugcccg ggcagggagc cuucgugcgg ucucagacag agaccaaagu cgaaccguuu     3300

gaggugccua acccccuucc ucugauuguc ggcagcuccg ucgggggacu ccugcuccug     3360

gcucuuauca cggccgcgcu guauaagcuc ggcuucuuua aaagacagua caaggacaug     3420

augagcgaag ggggaccccc gggcgcugag ccucaauga                            3459


<210>  676
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  676
auguucagcc ugaagacccu ccccuuucug cuucugcucc acgugcagau cuccaaagcc       60

uucccugucu cuagcaagga gaaaaacaca aagacgguuc aagacuaccu ggaaaaauuu      120

uaucagcuuc cguccaauca guaccagucu accagaaaga acggcacaaa ugugauugug      180

gagaagcuga aagaaaugca acgguucuuu gggcucaacg ucaccggaaa gcccaaugag      240

gaaacacugg auaugaugaa aaagccucgc ugcggcgugc ccgacagcgg gggauucaug      300

cugaccccug gcaaccccaa augggagaga acaaaucuca ccuaucggau ccgcaacuac      360

acgccucagc uguccgaggc ugaaguugag agagccauua aggaugcguu ugaacuuugg      420

ucuguggcua gcccgcugau cuucacccgg auuucccagg gggaggccga caucaauauc      480

gccuuuuauc agcgcgauca uggagacaac agccccuucg auggcccuaa uggcauucuc      540

gcucacgccu uucaacccgg gcagggaauc ggcggggacg cucauuucga ugccgaggaa      600

acauggacca acacaucugc gaauuacaac cuguuucuug ucgccgcuca cgaguucgga      660

cauucccugg gccucgccca cagcucugac ccuggggcuc ugauguaucc caauuacgcc      720

uucagagaaa ccuccaacua cagccugccg caggaugaca uugauggaau ccaggcgauu      780

uauggccucu cuuccaaccc uauccaaccc acgggcccua gcacacccaa gcccugugac      840

ccuucccuga ccuuugacgc cauuacaacc cuucggggag agauccuguu cuuuaaagau      900

cgcuacuucu ggagacggca cccgcagcuc cagcgcgugg aaaugaauuu uaucucucug      960

uucuggccca gccuuccuac cgggauucaa gcugccuaug aggacuuuga uagagaccug     1020

aucuuccucu uuaagggcaa ccaguacugg gcucuguccg gguaugauau ucugcaggga     1080

uaccccaaag acaucagcaa uuauggcuuc ccuucuuccg uucaggccau ugaugccgcu     1140

guguuuuacc ggagcaagac auacuucuuu gucaacgacc aauucuggcg cuaugauaau     1200

cagagacagu ucauggagcc cggguacccg aaaucuauca gcggagcguu uccuggcauc     1260

gaauccaagg uggacgccgu guuccagcaa gagcacuuuu uccaugucuu uucuggcccc     1320

cgguauuacg cuuucgaucu cauugcccag agaguuacgc gcguggcccg ggggaacaaa     1380

uggcugaauu gcagauaugg auga                                            1404


<210>  677
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  677
augagccugu ggcagccccu cgugcugguc cuucugguuc ucggcugcug uuucgccgcu       60

ccuagacaac ggcaguccac ccuggugcuu uuuccggggg accugcgcac aaaccucacg      120

gauagacagc uggccgagga auaccuguau cgguacggau auacccgcgu ggcggagaug      180

agaggcgaau cuaaaagccu cgggcccgcu cugcuucugc uccagaaaca acugucccuu      240

ccugagacag gagaacugga cucugccacc cucaaggcca ugcggacacc ccgcugcggc      300

gucccugauc uggggagauu ccagaccuuu gagggagacc ugaaauggca ccaucacaau      360

aucacauacu ggauucagaa cuauagcgag gaucuccccc gggcugugau cgacgaugcc      420

uucgcucgcg ccuuugcgcu gugguccgcc guuaccccuc uuacguucac cagaguguac      480

ucucgggacg cugauauugu cauccaguuu ggcguggccg aacauggcga cggguauccg      540

uucgauggaa aggacggccu gcucgcucac gccuuucccc cugggcccgg gauucaaggc      600

gaugcgcauu ucgacgacga ugagcugugg agccuuggga aaggaguugu ggucccuaca      660

cgcuuuggca augccgacgg cgcugccugu cacuuccccu uuaucuucga agggagaucc      720

uacagcgcuu gcaccacaga uggacggucu gacggccugc cgugguguuc caccacggcc      780

aacuacgaua cagacgaucg cuucggguuu ugcccuagcg agagacucua uacccaggac      840

ggaaaugccg auggcaagcc cugucaguuc ccuuuuaucu uccaggggca aucuuacucc      900

gcuugcacaa ccgacggacg gagcgauggc uauagauggu gugcgaccac agccaacuac      960

gaccgcgaca agcuguuugg cuucugcccc acgcgggcug auucuaccgu gaugggagga     1020

aauuccgccg gcgagcugug uguguuuccc uucacauuuc ucgggaaaga auauagcaca     1080

ugcaccuccg agggaagagg cgacgggcgc cuguggugcg ccaccacguc uaacuucgau     1140

agcgacaaga aauggggcuu uuguccugau cagggauacu cccuuuuccu ggucgcugcc     1200

cacgaauuug gccaugcgcu cgggcuggac cacagcucug uuccggaggc ucuuauguau     1260

cccauguacc gguucacaga aggaccuccc cugcauaagg augacgugaa uggcauuaga     1320

caccucuacg ggccucgccc cgagccggag ccucggcccc cuaccaccac aacaccccag     1380

ccuaccgcgc ccccgacggu gugcccuacc ggaccuccca caguccaccc cuccgaaaga     1440

ccgaccgccg gccccacagg gccucccagc gcuggcccua ccggaccccc uacggccggc     1500

cccucuaccg cuacaaccgu gccgcugagc ccuguugaug acgccuguaa cgugaauauc     1560

uucgaugcga uugccgagau cgggaaccaa cuguaucucu uuaaagacgg aaaguacugg     1620

cgcuucuccg aaggccgggg gucuagaccc cagggaccuu uucugauugc ugauaagugg     1680

cccgcccuuc cgcgcaaacu ggacagcguc uucgaggaac ggcucuccaa gaaacuguuu     1740

uucuuuagcg gcagacaggu guggguuuau acaggggcuu cugugcuggg cccucggcgc     1800

cuugacaagc ucggacuggg cgccgauguc gcccagguga ccggggcccu gagauccgga     1860

cggggcaaaa ugcuccuguu cagcgggaga cgccuuuggc gguuugacgu caaggcucaa     1920

augguggauc ccagaucugc cuccgagguu gaccgcaugu ucccuggagu gccccuggau     1980

acgcaugacg ucuuucagua cagagagaag gcuuauuucu gccaggaucg guuuuacugg     2040

cgcgugagcu ccagaucuga acucaaucag guugaccaag ugggcuaugu cacauacgau     2100

auccugcagu gucccgagga cuga                                            2124


<210>  678
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  678
augcaccccg gcgugcuggc cgcuuuccuc uuucugagcu ggacccauug cagagcccuu       60

ccucugccgu ccgggggaga cgaggaugac cucucugaag aggaucugca guucgcggaa      120

cgguaccuuc gcagcuauua ccaccccaca aaccuggcug gcauccucaa ggagaaugcc      180

gccuccucua ugacggaaag acugcgggag augcagagcu uuuucgggcu ggaggucacc      240

ggaaaacucg acgauaacac acuggacguu augaagaaac cucgcugugg cgugcccgau      300

gugggggaau auaaugucuu uccuagaacc cuuaaguggu ccaaaaugaa ccugacauac      360

cggauuguga auuauacccc cgacaugaca cauucugagg uugaaaaggc uuucaagaaa      420

gccuuuaagg uguggagcga ugucaccccu cucaacuuca cgcgccugca cgacggaauc      480

gcugauauua ugaucuccuu uggcauuaaa gagcauggcg acuucuaccc guuugauggg      540

cccagcggac uucuggccca cgcguucccu cccggcccua auuauggggg agacgcccac      600

uuugacgaug acgagaccug gacaucuucc agcaagggcu acaaccucuu ccugguggcu      660

gcccaugagu ucgggcacuc ucugggacuc gaucauucca aagaccccgg cgcucugaug      720

uuuccgaucu acaccuauac aggcaagagc cacuucaugc uuccugauga cgauguucaa      780

gggauccagu cucuguacgg acccggcgac gaggauccua aucccaagca ccccaaaacc      840

ccugacaagu gcgauccguc ccucagccug gacgccauua cgucccuuag aggggaaaca      900

augaucuuua aagaccgguu cuuuuggcgc cugcaucccc agcaagugga ugcggaacuc      960

uuccugacca agucuuuuug gccugaacug cccaacagaa uugacgccgc uuaugagcac     1020

ccuagccaug aucucaucuu cauuuuucgg ggacgcaaau ucugggcccu gaauggcuac     1080

gacauccuug agggguaucc caagaaaauu uccgaacugg gacucccgaa ggaggucaag     1140

aaaaucagcg cugccgugca cuuugaagau acaggcaaga cccugcuuuu cucuggcaac     1200

caggugugga gauacgacga uaccaaucau aucauggaca aagauuaucc ucggcugauu     1260

gaggaagacu uucccgggau cggagauaag gucgacgccg uuuacgagaa aaacggcuac     1320

auuuauuucu ucaaugggcc uauccaguuu gaguacucca uuuggagcaa ccgcaucgug     1380

agagugaugc ccgcuaacuc uauccucugg uguuga                               1416


<210>  679
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  679
auggagaccc ccaacacaac ggaagacuac gauaccacaa ccgaguucga cuauggcgau       60

gccacaccuu gccagaaggu gaaugaaaga gcuuuugggg cccaacugcu cccgccccug      120

uacagccuug ucuucguuau cggacuggug ggcaacauuc ucgugguccu ggugcuuguu      180

caguauaaac ggcugaagaa uaugaccucc aucuaccucc ugaaccuggc gauuucugac      240

cuccuguuuc uuuucacacu gccuuuuugg aucgauuaua aacucaagga cgauugggug      300

uucggggacg cuauguguaa aauucugagc ggauuuuacu auaccggccu uuacuccgag      360

aucuucuuua ucauucugcu cacgaucgau cgcuaccugg ccauugucca cgccguguuc      420

gcucugagag cccggaccgu uacauuuggg gugaucaccu cuauuaucau uugggcucuc      480

gccauccugg cgagcaugcc cggacuuuau uucuccaaga cacaguggga auuuacccau      540

cacacgugcu cucugcauuu cccucacgag agccuccgcg aguggaagcu guuccaggcc      600

cuuaaacuga aucucuuugg ccugguccug ccccuccugg ugaugaucau uuguuacaca      660

ggcaucauua agauccuucu gagacggccu aacgagaaaa aguccaaagc ugugcgccuc      720

auuuucguca ucaugaucau cuuuuuccug uuuuggaccc cguauaaucu uacaauucug      780

auuagcguuu uccaagacuu ucucuucacc caugaaugcg aacagucuag acaccuggau      840

cuggccgucc aggugaccga ggugaucgcu uacacacacu guugcgugaa ccccguuauu      900

uaugccuuug ugggggagcg guuccgcaag uaccucagac agcuguuuca ucggcgcguc      960

gcggugcacc uuguuaagug gcugccuuuc cucuccgugg acagacugga acgggucagc     1020

ucuacguccc ccagcaccgg agagcaugaa cugucugccg gcuuuuga                  1068


<210>  680
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  680
augagaaccc uggccugccu ccugcuucug ggcugugggu accucgcuca cgugcuggcc       60

gaggaagcgg agaucccccg ggaagucauu gagcgccuug cuagaagcca gauccauucc      120

auucgggacc ugcaacgccu ccuggaaauc gauucuguug gaagcgagga cucccuggau      180

acaucucuca gagcccacgg cgugcaugcc acgaagcacg ugccugagaa acggccgcug      240

cccauucgca gaaagcggag caucgaagag gcugucccug ccgugugcaa aacccgcaca      300

guuaucuaug aaauucccag aucccaggug gacccuaccu cugcuaacuu ccuuaucugg      360

cccccuugug ucgaggugaa gcggugcaca ggguguugca auaccagcuc cguuaaaugu      420

cagccgagcc gcgugcauca cagaucuguc aagguggcca agguggagua cguccggaaa      480

aagcccaaac ugaaggaagu ucaggugcgc cucgaggaac accuggagug cgcgugugcc      540

acaaccuccc uuaacccuga uuauagagaa gaggacacgg gacggcccag agagagcggc      600

aaaaagcgca agcggaaaag acugaagccu accuga                                636


<210>  681
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  681
augaacagau gcugggcccu guuccucagc cuguguugcu accuucggcu gguguccgcu       60

gagggcgacc ccaucccuga ggaacucuau gaaaugcugu cugaucacag cauucgcucc      120

uuugacgauc uucagagacu gcuccauggg gacccgggag aggaagaugg cgccgagcug      180

gaccugaaua ugacccgguc ucacagcggg ggagagcucg aaucccuggc gcgcggcaga      240

cggucucuug ggagccugac aaucgcugag cccgccauga uugccgaaug uaagacgcgc      300

accgaggucu ucgagaucuc cagacggcuc auugaucgca caaacgcuaa uuuucugguu      360

uggccucccu gcguggaagu gcaaagaugu agcggaugcu guaacaaucg gaacguccag      420

ugccgcccua cccaggugca gcuuagaccc guucaagugc ggaaaaucga gaucguccgc      480

aagaaaccua uuuucaagaa agccacagug acccuggaag accaucucgc uuguaagugc      540

gagacaguug ccgcggccag accggugacc cggucucccg gcggcuccca ggaacagaga      600

gcuaagacgc cucagacccg cgucacaauc cggaccguga gagugcgccg gcccccuaaa      660

gggaagcaca gaaaauuuaa gcauacacac gauaaaaccg cccugaagga gacgcuggga      720

gcuuga                                                                 726


<210>  682
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  682
augagccugu ucggccuccu gcuucugacc uccgcccucg cugggcagag acaaggaaca       60

caggccgagu cuaaccugag cuccaaguuu caguucucua gcaauaaaga acagaacggc      120

gugcaagacc cccagcacga gcggaucauu acggucucca ccaauggguc uauccauagc      180

ccucgcuuuc cgcacacaua ccccagaaac accguucuug uguggcggcu gguggcgguc      240

gaagagaaug uguggauuca gcucacauuc gaugaacgcu uuggacugga ggacccugag      300

gaugacaucu gcaaguauga uuucguugaa guggaggaac ccuccgacgg caccauucug      360

gggagauggu guggaagcgg cacagucccu ggcaaacaga ucucuaaggg gaaccaaauc      420

cggauucgcu uuguguccga ugaguacuuc cccagcgagc cuggauuuug cauccauuau      480

aauauuguua ugccgcaguu caccgaagcu gugucucccu ccguccuccc ucccagcgcc      540

cugccucuug accugcucaa caaugccauc acggcuuuuu cuacccugga ggaucuuauu      600

agauaccugg aacccgagcg guggcagcuc gaccuggaag aucuguaucg cccgacaugg      660

cagcuccugg gcaaagccuu cguguuuggg agaaaguccc ggguggucga ccuuaaccug      720

cucaccgagg agguucgccu guacagcugu acaccuagaa auuucuccgu gucuauccgg      780

gaggaacuua agcgcaccga uacgauuuuc uggcccggau gccugcucgu gaaaagaugu      840

ggcgggaacu gcgcuuguug ccugcacaau uguaacgaau gccaaugugu cccuagcaag      900

gugaccaaaa aguaucauga gguucugcag cuccggccca aaacaggagu gagaggccug      960

cacaaguccc uuacagacgu cgcccuggaa caccaugagg agugcgacug cgugugucgc     1020

ggcagcaccg ggggauga                                                   1038


<210>  683
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  683
augcacagac ugaucuucgu guacacccuc auuugcgcca acuuuuguag cugccgggac       60

acauccgcua cgccccaguc ugccagcauc aaggcgcugc gcaaugcuaa ccuuagacgg      120

gaugaccugu aucgcagaga ugagaccauu caagucaaag gcaaugggua cguucagucc      180

ccucgguucc cgaacucuua uccccgcaau cuccugcuua cauggagacu gcauagccag      240

gaaaacaccc ggauccagcu cguguuugac aaucaauucg gacuggagga agccgagaac      300

gauauuuguc gcuacgacuu uguggaaguc gaggauaucu ccgagacauc uaccaucauu      360

agaggccggu ggugcgggca caaggaagug ccuccccgca ucaaaagcag aacaaaucag      420

auuaagauca ccuucaaauc cgacgauuau uuuguugcca agccuggauu caagauuuac      480

uauagccugc ucgaggacuu ucagcccgcu gccgcuucug aaacgaacug ggaguccgug      540

accagcucua ucuccggcgu cagcuacaau ucuccuuccg ugacagaucc gacccugauu      600

gccgacgcgc uugauaaaaa gaucgccgag uucgacacag uugaagaccu gcucaaauac      660

uuuaaccccg agagcuggca ggaagaucug gagaauaugu aucuugacac cccucgguac      720

cgcgggagau ccuaucauga ucggaagucu aaaguggacc uggauagacu caacgacgau      780

gcuaagcgcu acagcuguac gccccggaau uauuccguca acaucagaga ggaacugaag      840

cuggccaacg ugguguucuu uccucgcugc cuccuggucc aacggugugg aggcaauugc      900

ggcuguggga caguuaacug gagaagcugc accuguaauu cuggaaaaac agugaagaaa      960

uaccacgagg ugcuucaguu cgaacccggc cauauuaagc gccgggggag agcuaaaacc     1020

auggcccugg ucgacaucca gcucgaucac cacgagcgcu gcgacugcau uuguuccagc     1080

cggccgccua gauga                                                      1095


<210>  684
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  684
auggugaccc acagcaaguu ccccgccgcu ggcaugucca gaccucugga cacaucucuc       60

cggcugaaaa cguuuagcuc caagucugag uaccagcuug ucguuaacgc cgugcgcaaa      120

cugcaagaaa gcggguucua uugguccgcg gugaccggag gcgaggcuaa ucuccugcuu      180

ucugccgaac cggccgggac auuucugauc agagauagcu ccgaccagcg gcauuucuuu      240

acccucagcg ucaagacaca gucuggaacc aaaaaccugc gcauucagug cgagggcggg      300

uccuucagcc ugcaaucuga ucccagaucc acacagccug ugccccgguu ugacuguguu      360

cucaagcugg ugcaccauua caugccuccc ccuggagcuc cgagcuuccc cucuccuccc      420

accgaaccuu ccagcgaggu ccccgagcag ccguccgccc agccucuucc cggcucuccu      480

ccccgcagag cuuauuacau cuauagcggc ggggaaaaga uuccccuggu gcucucccgg      540

ccucugagcu cuaauguugc cacgcuucaa caccugugcc gcaaaaccgu gaacggacau      600

cucgauuccu acgagaaggu cacacagcug ccgggcccca ucagagaauu ucuggaccag      660

uaugaugcgc cucucuga                                                    678


<210>  685
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  685
auggugccca gcgccggcca gcuggcucuc uucgcccugg ggaucguccu ugcggcuugc       60

caagcccugg agaacuccac cucuccucuc agcgccgacc cgcccguugc ugccgcugug      120

gugucccacu uuaaugauug uccugacucu cauacacagu ucugcuuuca cggaacgugu      180

agauuccugg uccaggaaga uaagcccgcc ugcguguguc auagcggcua cguuggggcg      240

cggugcgagc acgccgaccu ucuggcugug gucgccgcuu cccagaaaaa gcaagccauu      300

accgcgcucg ugguuguguc uaucgucgcc cuggcugugc ugauuaucac augugugcuc      360

auucauugcu gucagguccg caaacacugc gaauggugua gagcccugau cugccggcac      420

gagaagccua gcgcccuucu gaaaggacgc accgcuugcu gucauuccga aacaguugug      480

uga                                                                    483


<210>  686
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  686
augcccccua gcggccugag acuccugccg cuucugcucc cccugcuuug gcugcucgug       60

cugaccccug ggcggcccgc cgcuggacug uccacaugca agacgaucga cauggagcuc      120

gucaaacgca agagaauuga agccauccgg ggccagauuc ugucuaaacu ucgccuggcg      180

agcccucccu cccaagggga gguuccuccg ggaccccucc cugaagcugu gcuggcccuu      240

uacaacucua ccagagaucg gguggccggc gagagcgcug aacccgagcc ugagcccgaa      300

gccgacuauu acgcuaagga ggucacacgc gugcugaugg uugaaaccca caaugagauc      360

uaugauaaau ucaagcaguc cacacauucu auuuacaugu uuuucaacac cagcgagcuc      420

agagaagccg ugccggagcc uguccugcug ucccgggcgg aacuccgccu gcuuagacug      480

aagcucaaag uggagcagca cguugaacug uaucagaagu acagcaauaa cucuuggcgg      540

uaucuuucca aucgccugcu cgcccccagc gacucuccug aguggcuguc cuuugaugug      600

acaggggucg ugagacaaug gcugagccgg ggaggcgaga ucgaaggcuu ccgccucucu      660

gcucauuguu ccugcgacag cagagauaac acccuucagg uggacaucaa uggguuuacg      720

accggacgga gaggcgaucu ggccacaauu cacgggauga accgccccuu ccugcuccug      780

auggcuacac cccuugagcg ggcccagcau cugcaguccu cuagacaccg ccgggcgcuc      840

gacaccaauu acuguuuuag cuccaccgag aaaaacugcu gugucagaca acuguacauc      900

gauuuccgca aggaccuggg auggaaaugg auucacgaac cuaagggcua ucaugccaau      960

uuuugccucg ggccgugucc cuacaucugg agccuggaua cgcaguauuc uaagguucuu     1020

gcucuguaca accagcacaa uccuggagcc uccgcugccc ccugcugugu gccucaggcc     1080

cucgaacccc ugccgauugu guauuacguc ggccggaaac cuaaggugga gcaacugagc     1140

aacaugaucg uuagaucuug caaauguagc uga                                  1173


<210>  687
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  687
augcacuacu gcgugcugag cgccuuccuc auccugcauc uugucaccgu ugcucugucc       60

cucucuacau guagcacgcu ggacauggau caguuuauga gaaagcggau ugaggccauc      120

cgcggccaaa uucuuuccaa acugaagcuc accucucccc cugaagacua uccggagccc      180

gaagaggugc cucccgaagu gaucagcauu uacaacucca caagagaucu gcugcaggag      240

aaagcgucuc ggcgcgcugc cgccugcgag agagaacgga gcgacgagga auauuacgcu      300

aaggaggucu auaaaaucga uaugccuccc uucuuuccuu ccgagaaugc caucccgccc      360

accuucuacc gcccuuauuu uagaauugug cgguucgacg uuagcgcuau ggaaaagaac      420

gccucuaauc ucgugaaggc ggaguuucgc gucuucagac ugcagaaccc caaagcccgg      480

gugccugaac agcgcaucga gcuuuaccaa auucugaagu ccaaagaucu cacaagcccc      540

acccagagau acaucgacuc uaagguugug aaaacacggg cugaagggga guggcugucc      600

uuugauguca ccgacgccgu gcacgagugg cuucaucaca aggaucgcaa ucugggauuc      660

aagauuagcc uccauugucc gugcuguacg uuugugccuu cuaacaauua uaucauuccc      720

aacaaauccg aggaacugga agcuagauuc gccggcaucg acgggaccag cacauacacc      780

uccggagauc agaagacaau caaaucuacc cggaagaaaa auagcggcaa gacgccucau      840

cugcuccuga ugcuucugcc cuccuauaga cucgagagcc agcaaacaaa ccgccggaaa      900

aagagagcgc uggacgccgc uuacugcuuu cgcaaugucc aggacaacug uugccuucgg      960

ccccuguaua uugauuucaa gagagaccuc ggguggaaau ggauccacga accuaaggga     1020

uacaaugcca acuucugugc uggcgccugc ccguaucugu ggucuuccga uacccagcac     1080

agccgcguuc ugucucucua caauacaauu aaccccgagg ccagcgcuuc cccuuguugc     1140

gugucucagg accuggagcc ccuuaccauc cuguacuaua uuggcaaaac cccuaagauc     1200

gaacaacuca gcaacaugau cgugaaaucc ugcaagugua gcuga                     1245


<210>  688
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  688
augaagaugc accuucagag agcccucgug guccuggcuc ugcugaacuu cgccaccguu       60

agccucuccc ugucuacaug cacgacccuu gacuuuggcc auaucaaaaa gaaacgggug      120

gaggcgauuc gcgggcaaau ccugagcaag cucagacuga caucuccccc ugaaccgacc      180

gugaugacac acguccccua ccaggugcug gcucucuaua auuccacccg ggagcugcuu      240

gaagagaugc auggagaacg cgaggagggc uguacacagg aaaacaccga gagcgaauac      300

uaugccaaag agauucacaa guucgauaug auccaggggc uggccgagca uaaugaacuc      360

gcuguuugcc cuaagggaau uacguccaaa guguuuagau ucaacgucuc uagcguggag      420

aagaaucgga ccaaccuguu ucgcgccgag uucagaguuc uucgggugcc caauccuucc      480

agcaaacgca acgaacaaag aaucgaacug uuucagaucc uccggcccga cgagcacauu      540

gcuaagcagc gcuacaucgg cgggaaaaau cugccuacaa gaggaaccgc cgaguggcug      600

ucuuucgaug ucacagacac cgugcgggaa uggcuccugc gcagagaguc caaccuuggc      660

cuggaaauua gcauccacug uccgugccau acguuucagc ccaauggcga uauucucgag      720

aacauccacg aagugaugga gauuaaguuc aagggggucg acaaugagga ugaccaugga      780

cggggcgauc uggggagacu uaaaaagcaa aaagaccacc acaacccuca ucugauccuc      840

augaugauuc ccccucaccg ccuggauaau cccggacagg gcgggcagcg gaagaaaaga      900

gcgcuggaca caaacuauug uuuucgcaac cucgaagaga auugcugugu ucggccgcug      960

uacaucgauu ucagacagga ccuuggaugg aagugggugc augaaccuaa aggcuauuac     1020

gccaacuuuu gcucuggccc cuguccuuac cugcgcuccg cugacaccac acacagcacc     1080

gugcucgggc uguauaauac ccuuaacccc gaggccucug cuucccccug cugugucccu     1140

caagaucugg aaccgcucac aauccuguac uaugugggac ggacgcccaa gguugagcag     1200

cugagcaaua ugguggucaa guccugcaaa ugcucuuga                            1239


<210>  689
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  689
auggcccccg uggcugucug ggccgcgcug gcuguuggcc ucgagcugug ggccgccgcu       60

cacgcccuuc cugcucaggu ggccuucacc ccguacgcgc ccgaaccugg gagcacaugc      120

agacugcggg aguauuacga ccaaacggcc cagauguguu gcuccaagug uucucccgga      180

cagcaugcua aaguguuuug caccaagaca agcgauaccg ucugugacuc cugcgaagau      240

ucuacauaua cccagcucug gaacugggug ccugaguguc ugagcugcgg cucccgcugu      300

ucuagcgacc aaguugaaac acaggccugc accagagagc agaaucggau cuguacgugc      360

cgccccgggu gguacugcgc ucuuuccaaa caggagggau guagacugug cgccccucuc      420

cggaaguguc gcccgggcuu cgggguggcg agacccggaa ccgaaacaag cgaugucgug      480

ugcaaaccuu gugcccccgg caccuuuucu aacacaaccu ccagcacgga cauuugccgg      540

ccucaccaaa ucuguaaugu uguggcuauu cccggcaacg ccucuaugga ugcugucugc      600

acauccacca gcccgacacg cucuauggcc ccuggggccg ugcaucugcc ccagccugug      660

uccaccagaa gccagcacac ccagcccaca cccgagccuu ccacggcucc gucuaccagc      720

uuccugcucc ccaugggacc uuccccuccc gcggaaggca gcacagggga cuuugcccug      780

cccgucggac uuaucguugg cgugaccgcu cuggggcucc ugauuaucgg aguggucaau      840

ugugugauca ugacacaagu uaagaagaaa ccgcuuugcc ugcagcggga ggccaaggug      900

ccucaucucc ccgccgauaa agcucgcggc acccagggcc cugagcaaca gcaucugcug      960

auuacggccc ccucuuccag cucuagcucc cucgaaucua gcgcguccgc ucuggacaga     1020

cgggccccua cacgcaacca gccccaggcc ccgggggucg aggcuagcgg agccggcgaa     1080

gcuagagccu cuaccggguc cagcgauucu uccccuggag gccacgggac ccaagugaau     1140

guuacaugua ucgugaacgu cugcagcucc ucugaccaca gcucccagug cucuagccag     1200

gcguccagca ccaugggaga uacagacucu ucccccagcg agucucccaa ggacgaacag     1260

gugccuuucu ccaaagagga gugugccuuu cggagccaac uugaaacgcc ggagacccug     1320

cucggcucua cagaagagaa gccccugccu cuuggcgucc ccgaugcugg gaugaagccu     1380

agcuga                                                                1386


<210>  690
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  690
augcccguga ugagacuguu cccuugcuuu cuccagcugc uugccggccu ggcucucccg       60

gccguucccc cucaacagug ggcgcugagc gcugggaacg gauccucuga ggucgaagug      120

gugcccuucc aggaggucug gggccggagc uacugucgcg cccuugaaag acugguggac      180

guuguguccg aguauccuuc ugaagucgag cacauguuua gccccuccug cgugucucuc      240

cugcggugua ccgggugcug uggagaugag aaucugcauu gcguuccugu ggaaacagcc      300

aacgucacga ugcagcuccu gaagauccgc agcggcgaca gaccguccua cguggagcuu      360

accuucagcc aacacgugcg gugugaaugc cgcccccuga gagagaaaau gaagccugag      420

cggcgcagac ccaaagggcg gggaaagcgc agacgggaaa aacagcgccc uacagauugu      480

caucucugcg gcgacgcugu ccccagacgg uga                                   513


<210>  691
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  691
augaccgaca gacagacaga uacggccccc agcccuuccu accaccuucu cccgggccgg       60

cgcagaaccg uggacgcugc cgcgucucgg gggcaaggac ccgagccugc ucccggcggg      120

ggagucgaag gcguuggggc ccgcggagug gcccugaagc uguucgugca gcugcucggc      180

ugcagcagau uuggcggggc ugucgugcgg gccggagagg cugaaccuuc cggcgccgcg      240

cgcucugcca gcuccgggag agaggaaccc cagccugagg agggagaaga ggaagaggag      300

aaagaagagg aacggggccc gcaguggcgc cugggggcua gaaagcccgg aucuuggaca      360

ggcgaggccg cuguuugugc cgauagcgcg ccugccgcuc gggcucccca agcccuugcc      420

cgcgccuccg gcagaggggg acggguggcu cgcagaggcg cggaagagag cgggccuccc      480

cauucuccgu cccggagagg aagcgccucu cgcgcuggcc cugggcgggc cuccgagacc      540

augaacuucc ugcucagcug gguccacugg ucucuggccc ugcuccugua ucuucaucac      600

gcuaaauggu cccaggccgc gcccauggcu gaaggaggcg gccagaauca ucacgaggug      660

guuaaguuua uggacgugua ccagagaagc uauugccacc cuaucgaaac acuggucgau      720

auuuuccaag aguaccccga cgaaaucgag uauauuuuua aacccuccug ugugccucuc      780

augcgcugcg ggggauguug caacgaugag ggccuggaau gugugccgac cgaggaaucu      840

aauaucacaa ugcagauuau gcggaucaag ccccaucagg ggcagcacau cggagagaug      900

agcuuccuuc aacauaacaa gugcgaaugu agaccuaaaa aggaccgcgc ccggcaggag      960

aaaaaguccg ucagaggcaa agggaagggc cagaagcgca aacggaagaa aagcagauac     1020

aagucuuggu ccguuuaugu gggagcccgc ugcugucuga ugcccuggag ccucccuggc     1080

ccccacccgu gcgggccuug cucugagcgg agaaaacacc uguuugugca agauccccag     1140

accuguaagu gcagcuguaa aaauacggac ucccggugca aggcucgcca gcuggaacuc     1200

aacgagagaa ccugucggug cgauaagccu agacgcuga                            1239


<210>  692
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  692
augaacuucc ugcucagcug ggugcacugg ucccuggccc uucugcucua ccugcaucac       60

gcuaaguggu cucaggccgc gcccauggcu gagggcgggg gacaaaauca ucacgaaguc      120

guuaaauuua uggacgugua ucagagaagc uacugccauc cuaucgagac ccuuguggau      180

auuuuccagg aauauccgga cgagaucgaa uacauuuuua agcccuccug ugucccucug      240

augcggugcg gcggguguug caacgaugag ggacucgagu gugugcccac agaagagucu      300

aauaucacga ugcagauuau gcgcaucaaa ccucaccaag gccagcacau cggggaaaug      360

agcuuccugc agcauaacaa gugcgagugu agacccaaaa aggaccgggc ccgccaggag      420

aagaaauccg uuagaggaaa gggcaaaggc caaaagcgga aacgcaagaa gucuagauau      480

aaaagcuggu ccguguacgu cggggcccgg ugcugucuga ugccuuggag ccucccggga      540

ccccacccuu gcggccccug uucugaacgc agaaagcauc uguuugugca ggauccucag      600

accugcaaau gcuccuguaa gaauacagac agccggugca aagcucgcca gcuugagcug      660

aacgaaagaa ccugucggug cgauaagccc cgcagauga                             699


<210>  693
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  693
augagccccc ugcucagacg gcugcuucug gccgcucucc ugcagcuugc cccugcgcaa       60

gcuccggugu cccagcccga cgccccuggc caccagcgca aggucguuuc uuggaucgau      120

guguacacca gagccacaug ccagccccgg gagguggucg ugccucugac gguugaacuc      180

auggggaccg uggcuaagca acuggucccc agcuguguga caguucagcg cugcggaggc      240

uguugcccug acgaugggcu ggagugugug ccgaccggac agcaucaggu cagaaugcaa      300

auucucauga uccgguaucc cuccucucag cugggcgaaa ugagccuuga ggaacacucc      360

cagugcgagu gucgcccuaa gaaaaaggac ucugccguga aacccgauag agcugccaca      420

ccucaucacc ggccccagcc gcgcagcgug ccuggguggg acuccgcgcc cggagccccu      480

agccccgcug auauuaccca ucccaccccu gccccgggcc ccucugcuca cgccgcgccu      540

uccacaacga gcgcccugac ccccggcccu gcugccgcug ccgccgacgc ugcggccucu      600

uccgucgcua aagggggagc cuga                                             624


<210>  694
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  694
augcaucugc ucggcuucuu uagcguggcc ugcucccugc uugcugccgc gcugcucccc       60

gggccuagag aggcuccggc cgccgcugcc gcuuucgaau cuggacugga ccuuagcgau      120

gccgagcccg acgcgggcga agccaccgcu uacgccucca aggaucugga ggaacagcuc      180

cggucuguca gcuccguuga cgagcugaug acagugcugu auccugagua cuggaaaaug      240

uauaaguguc aacuccgcaa agggggaugg cagcacaaca gagaacaggc uaaucugaac      300

ucucggacgg aggaaaccau caaguuugcc gcggcccacu acaauacaga gauucuuaaa      360

agcaucgaua acgaguggcg caagacccag ugcaugccca gagaagugug uauugacguc      420

ggcaaggagu ucgggguggc uacaaauacc uuuuucaaac cucccugcgu uuccguguau      480

cgguguggag gcugcuguaa cagcgaaggc cugcaaugca ugaauacauc uaccuccuac      540

cucagcaaga cgcuguuuga gaucaccguc ccucuuucuc aggggccgaa acccgugaca      600

auuuccuucg ccaaccauac cagcugucgc ugcaugucua agcuggaugu uuauagacag      660

gugcacucca ucauccggcg cagccucccu gcuacacugc cccaguguca agccgccaau      720

aaaaccugcc cuacgaacua cauguggaau aaccauauuu gcagaugucu ggcucaggaa      780

gacuuuaugu ucuccucuga ugcgggagac gauagcacag acggcuuuca cgauaucugc      840

gggcccaaua aggagcucga cgaggaaacc ugucagugcg ucugucgggc cggacugcgc      900

ccggcuuccu gcggcccuca caaggagcuu gacagaaaca gcugucagug cguguguaaa      960

aauaagcugu uccccucuca augcggggcc aaccgggaau uugaugagaa cacaugucag     1020

ugcgugugca aacgcaccug uccuagaaau cagccccuca accccggaaa gugcgccugu     1080

gaaugcaccg aguccccuca aaaaugucug cuuaagggca aaaaguucca ucaccagaca     1140

ugcagcuguu accggagacc gugcacgaau cgccagaagg cuugugagcc cggcuucucu     1200

uauagcgaag aggucugccg guguguuccu uccuacugga aaagacccca gaugucuuga     1260


<210>  695
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  695
auguacagag aguggguggu cguuaacgug uucaugaugc uguaugugca gcucguccaa       60

ggcagcucca augaacacgg gcccgugaag cggucuagcc aguccacccu ggagcgcucu      120

gaacagcaga ucagagccgc uagcucccuu gaggaacugc uccggauuac acauucugag      180

gacuggaaac uguggcgcug cagacuucgg cucaagagcu uuacguccau ggauagccgc      240

ucugccuccc acagaagcac ccgguucgcg gcuacauuuu acgacaucga gacccugaaa      300

guuauugaug aagaguggca acgcacacag uguucuccua gagaaaccug cguggagguc      360

gccuccgagc ugggaaagag cacaaacacc uucuuuaaac cgcccugugu gaauguuuuc      420

cggugcggcg gguguugcaa cgaagagucu cugaucugua ugaauacguc caccagcuau      480

auuuccaagc agcucuuuga aaucucugug ccucugacaa gcguccccga gcuugugccu      540

gugaaggucg ccaaccauac cggaugcaaa ugucugccca cagcuccucg ccacccguac      600

uccaucauua gacggagcau ccagauuccc gaagaggacc gcugcucuca uuccaagaaa      660

cucuguccua ucgauaugcu gugggacagc aauaagugca aaugcguucu ucaagaggaa      720

aacccccugg ccggcaccga ggaucacucu caccuccagg aaccugcucu gugugggccc      780

cauaugaugu ucgacgagga uagaugcgaa ugugugugca agacgccgug uccuaaggac      840

cugauucagc accccaaaaa uugcagcugu uuugagugca aggagucccu cgaaacaugu      900

ugccagaaac auaagcuguu ccacccugau accuguucuu gcgaggaccg gugccccuuu      960

cacacaagac ccugugccag cggaaaaacc gcgugcgcca agcauugucg cuucccuaaa     1020

gaaaagcggg cugcccaagg cccgcacucc agaaagaacc ccuga                     1065


<210>  696
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  696
auggcaguaa uggcaccaag aacauuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg ca                                                           72


<210>  697
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  697
auggaugcua ugaaaagagg uuuauguugu guuuuauuau uauguggagc uguauuugua       60

aguccaagu                                                               69


<210>  698
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  698
auggguguac augaaugucc agcuuggcuu uggcuuuuac uuucacuuuu aucuuuaccu       60

uuagguuuac cuguacuugg a                                                 81


<210>  699
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  699
augaaauggg uuacuuuuau uucucuucuu uuucuuuuuu cuucugcuua cucu             54


<210>  700
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from 
       Artificial____cleavage site-Furin

<400>  700
agaaggagga gaaaaaga                                                     18


<210>  701
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  701
auggacucag acgaaacagg auuugaacac ucaggauuau ggguaucagu auuagcagga       60

uuacuacucg gagcaugcca agcacaccca aucccagacu caucaccauu auuacaauuc      120

ggaggacaag ucagacaacg auacuuauac acagacgacg cacaacaaac agaagcacau      180

uuagaaauaa gagaagacgg aacaguaggc ggagcagcag aucaaucacc agaaucacua      240

cuacaacuaa aagcacuaaa accaggagua auacaaauau uaggaguaaa aacaucaaga      300

uucuuaugcc aaagaccaga cggagcacua uacggaucau uacacuuuga uccagaagca      360

ugcucuuuca gagaacuacu acuagaagac ggauacaacg uauaccaauc agaagcucau      420

ggacuaccuu uacaccuacc aggaaacaaa ucaccacaca gagauccagc ucccagagga      480

cccgcaagau uccuaccauu accaggauua ccaccagcau uaccagaacc accaggaaua      540

cuagcaccac aaccaccaga cguaggauca ucagacccau uaucaauggu aggaccauca      600

caaggaagau caccaucaua cgcaucauaa                                       630


<210>  702
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  702
augcacucau uuccaccacu auuauuacua cuauuuuggg gagucguauc acauagcuuu       60

cccgcaacac uagaaaccca agaacaagac guagacuuag uacaaaaaua ucuagaaaaa      120

uacuauaacc ucaaaaacga cggaagacaa gucgaaaaaa gaagaaacag cggaccaguu      180

guagaaaaac uaaaacaaau gcaagaauuu uucggauuaa aaguuacugg aaaaccagac      240

gcagaaacac uaaaaguaau gaaacaacca agaugcggag uaccagaugu agcacaguuc      300

guauuaacag aaggaaaccc acguugggaa caaacacauc uuacauacag aauugaaaau      360

uacacaccug accuaccaag agcagacgua gaccacgcaa uagaaaaagc cuuucaauua      420

uggucaaacg uaacaccauu aacauucaca aaaguuucug aagggcaagc agacauaaug      480

aucucauuug uuagaggaga ccaccgagac aauagcccau ucgacgggcc aggaggaaac      540

cuagcacaug cuuuccaacc aggaccugga auaggaggcg acgcacauuu cgacgaagac      600

gaacgaugga caaacaauuu cagagaauac aaccuacaua gaguagcagc ccacgaauua      660

ggccacagcc uaggcuuauc acacucaaca gacauuggag cucuaaugua cccuuccuac      720

acauuuucag gagacguaca auuagcccaa gacgauauag acggaauaca agcaauauac      780

ggacgaucac aaaacccagu acaaccaaua ggaccacaaa caccaaaagc augcgacuca      840

aaauuaacau uugacgccau aacaacaaua agaggagaag uaauguuuuu caaagaccga      900

uuuuauauga gaacaaaucc auucuaccca gaaguagaau uaaacuuuau aaguguauuc      960

uggccucaau uaccaaacgg auuagaagca gcauaugaau uugcagacag agacgaagua     1020

cgauucuuua aaggaaauaa auacugggcc guacaaggac aaaacguauu acauggauac     1080

ccaaaagaca uauacagcuc auucggguuu ccaagaacag uaaaacacau agacgccgca     1140

uuaucagaag aaaacacagg caaaacauau uuuuucguag caaacaaaua cuggagauac     1200

gacgaauaca aaagaucaau ggacccagga uauccaaaaa ugauagcaca cgauuucccu     1260

ggcauugggc acaaaguaga ugcaguauuc augaaagaug gcuuuuucua cuucuuucac     1320

ggaacucgac aauacaaauu cgacccaaaa acaaaaagaa uacucacacu acaaaaagca     1380

aacaguuggu ucaauuguag aaaaaacuaa                                      1410


<210>  703
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  703
augcauucau ucccaccacu acuauuauua uuauucuggg gaguaguauc acauucauuu       60

guacuaacug aaggaaaucc uagaugggaa caaacucacu uaaccuauag aauagaaaac      120

uauacaccag accuaccaag agccgacguc gaccacgcaa uugaaaaagc auuccaauua      180

uggaguaacg uaacaccacu aacauucaca aaaguaucag aaggacaagc agacauaaug      240

auaucauuug ucagaggaga ccaccgagac aacucaccau uugacggacc uggaggaaau      300

cucgcacacg cauuccaacc aggaccagga auaggaggag acgcacauuu ugaugaagau      360

gaacgaugga ccaacaauuu uagagaauac aaccuacacc gaguagccgc acacgaacuc      420

ggacacagcc uaggacuauc acacucaacc gacaucggag cacuaaugua cccaucauac      480

acauucuccg gagacgucca acuagcucaa gacgacauag acggaauaca agcaauauac      540

ggaagaucac aaaauccugu acaaccaaua ggaccacaaa ccccaaaagc augcgacuca      600

aaauuaacau uugacgcaau aaccacaauu agaggugaag uaauguuuuu caaagauaga      660

uuuuacauga gaacaaaucc cuucuaucca gaaguagaau uaaauuucau aucaguauuc      720

uggccacaac uaccaaaugg auuagaagca gcauacgaau uugcagauag agacgaagua      780

agauucuuca aaggcaacaa auacugggca guacaaggcc aaaacguacu acacggauau      840

ccuaaagaca uauacucuuc cuuuggauuu ccuagaacag uaaaacacau agaugccgca      900

cuaucagaag aaaacaccgg aaaaacauac uucuucgucg ccaauaaaua cuggagauac      960

gacgaauaua aacgaucaau ggacccaggu uacccaaaaa ugauagcaca cgauuuccca     1020

ggaauaggac acaaaguuga cgcagucuuu augaaagacg gauuuuucua cuucuuucac     1080

ggaacacgac aauacaaauu cgaucccaaa acuaaaagaa uccuaacuuu acaaaaagcc     1140

aauucuuggu uuaauuguag aaaaaacuaa                                      1170


<210>  704
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  704
augaaaaaaa acauacucaa aauucuaaug gacucauacu cgaaagaauc aaaaauacaa       60

acaguccgca gaguuacauc agucucguua cuagcaguau accugacgau gaacacaucc      120

ucguuaguac ucgcuaaacc uauagaaaau accaacgaua ccaguauaaa aaacguagaa      180

aaauuaagaa augcaccaaa cgaagaaaac aguaaaaaag uagaagacag uaaaaaugac      240

aaaguagaac auguaaaaaa cauagaagaa gcaaaaguug aacaaguagc accagaggua      300

aaauccaaaa gcacauuaag aagcgcguca aucgccaaca caaauucaga gaaguacgac      360

uucgaauacu uaaacggauu aaguuauaca gaacuaacaa aucucauuaa aaauaucaaa      420

uggaaccaga uaaauggacu auuuaauuac ucaacaggau cacaaaaauu uuucggagac      480

aaaaauagag uacaagcaau uauaaacgcu uuacaagaaa gcggacgaac guauacagca      540

aacgauauga aaggaauuga aacauucaca gaaguacuac gcgcugguuu uuaucugggc      600

uauuauaacg acggacuauc auaccucaac gaccgaaacu uccaagauaa augcauacca      660

gcgaugauug caauucaaaa aaacccaaac uuuaaacuag gaaccgcagu ccaagaugaa      720

guaauaacgu cgcucggaaa acuaauagga aaugcaagcg cuaaugcaga aguuguaaau      780

aacuguguuc ccguacuaaa acaauuccga gaaaauuuaa aucaauacgc accagauuac      840

gucaaaggaa cggccguuaa ugaacuuauc aaaggaauag aauuugauuu cucaggagca      900

gcuuaugaaa aagacguaaa gacuaugcca ugguacggaa aaauagaucc cuuuauaaau      960

gagcugaagg cacuaggccu uuacggaaac aucacaucag cuacagaaug ggcgucagau     1020

gucgggauau acuaucuauc aaaauucgga cuuuacucaa ccaaccgaaa ugauauagua     1080

caauccuuag aaaaagcagu agauauguau aaauacggaa aaauagcuuu cgucgcaaug     1140

gaacgaauca caugggauua ugacgguaua ggaagcaaug gaaaaaaagu agaucaugac     1200

aaauuccuag augacgcaga aaaacauuac cuccccaaaa cauacaccuu cgauaacggc     1260

acauucauaa uaagagcugg agacaaagua ucagaagaaa aaaucaaacg uuuauacugg     1320

gcaucacgag agguuaaauc acaauuccau agaguagucg guaaugacaa agcauuagaa     1380

guaggcaaug cagacgacgu acucacaaug aaaauauuca auucuccuga agaauauaaa     1440

uuuaauacca acauuaacgg aguaucuaca gacaauggag gccuuuacau agaaccaaga     1500

ggaacguucu auaccuacga aagaacacca caacaaucaa ucuuuucauu agaagaacua     1560

uuuagacacg aauacacaca cuaucugcaa gcacgauacc ugguggaugg acuaugggga     1620

caagggccau uuuaugaaaa aaaccgcuua acaugguuug augaaggcac agccgaauuu     1680

uucgcaggau caaccagaac aucggguguc uuaccacgga aaucaauacu cggguacuua     1740

gcaaaagaca aaguagauca uagauauuca uuaaaaaaaa cacuaaauag uggauaugau     1800

gacucggauu ggauguuuua caacuauggu uuugcgguag cacauuauuu auaugaaaaa     1860

gauaugccca cauucauaaa aaugaacaaa gcuauauuaa auaccgaugu aaagagcuau     1920

gaugaaauaa uaaaaaaacu cagugaugau gcaaauaaaa acacugaaua ucaaaaccac     1980

auacaagaac uagcagacaa auaccaagga gcagguauuc cguuaguuuc agaugauuac     2040

uuaaaagacc acggauauaa aaaagcauca gaaguauaca gugaaauauc gaaagcagcc     2100

agccuuacaa acaccucagu aacagcagag aaaagucaau auuucaacac auuuacacua     2160

agaggaacau acacggggga aaccucaaaa ggagaauuua aagauuggga ugaaaugucc     2220

aaaaaacuag acggaacacu agagagcuua gcuaaaaaca guuggagcgg auacaaaacu     2280

uuaacggcau acuuuacuaa cuaccgaguu acaagugaca auaagguuca auacgacgua     2340

guauuucacg gaguacuaac agacaacgcu gauauuagua acaacaaagc gccuaucgcu     2400

aaaguaacag gaccaucgac uggggcaguc ggaaggaaca uagaauuuuc ugggaaagac     2460

aguaaagaug aagacggaaa aauaguuagu uacgauuggg auuuuggcga uggagcuacc     2520

ucucguggaa agaacucugu gcaugcauac aaaaaagcag gaacauauaa cguaacccua     2580

aaaguaacag acgacaaagg agcaacagcu acagagagcu uuaccauaga aauaaaaaac     2640

gaagauacaa cgacaccaau aacaaaagag auggaaccua augaugacau aaaagaagcu     2700

aacggaccca uaguggaagg aguaacagug aaaggagacc ugaauggcag cgaugacgcu     2760

gauacuuuuu auuucgaugu caaagaagac ggugacguaa ccauugaacu accguacagc     2820

ggcaguucaa auuuuacaug guugguauau aaagaaggag acgaccaaaa ccacauagca     2880

ucuggaauag auaaaaauaa cucaaaaguu gguacauuua aaaguacaaa agguagacac     2940

uauguauuca ucuauaaaca cgacagcgca ucaaacauau ccuauucccu caauauaaag     3000

ggacuaggaa augaaaaacu gaaagaaaaa gaaaauaacg auuccaguga caaagcaacu     3060

guaaucccaa auuuuaauac aacaaugcaa ggaucuuuau uaggagacga uagucgcgac     3120

uauuacucau uugaagugaa agaagaagga gaaguaaaua uagaacuuga caaaaaagac     3180

gaguucggag uaaccuggac ucuccaccca gaaucaaaua uaaacgauag aaucacauac     3240

ggacaaguag acgguaacaa agucucaaau aagguaaaac uuagaccagg gaaauacuau     3300

uuacucguau auaaauacuc uggcagcggc aacuacgagu uacggguuaa caaauaa        3357


<210>  705
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  705
augaaauggg ucaccuuuau aagucuacuu uucuuauuuu ccucagcaua uagcauagca       60

aauacaaauu ccgaaaaaua ugacuucgaa uaccuaaacg gucuuaguua cacagaauua      120

acuaaccuaa uuaaaaacau aaaauggaau caaauaaaug gcuuauuuaa uuauucaaca      180

gguagucaaa aauucuucgg agauaaaaac agagugcaag caauaauaaa cgcccuacaa      240

gagucaggac gaacauauac agcaaaugac augaaaggaa uagagacauu cacagaggua      300

uuacgugccg gauucuaccu aggauacuac aacgacgguu uaucuuacuu aaaugacaga      360

aacuuccagg auaaauguau accagcaaug auagcaauac agaaaaaccc uaauuucaaa      420

cucggaacgg cgguucaaga cgaaguaauu acaucuuuag guaaauugau aggaaacgca      480

ucagcgaacg ccgagguagu aaacaauugc guaccggucc uuaaacaauu uagagaaaau      540

cuaaaccaau augcaccaga cuacgugaaa ggaacagcag ugaaugaauu aauaaaaggc      600

auugaguucg acuucucagg agcagcauau gaaaaagaug uaaaaacaau gccaugguac      660

ggaaaaauag auccauucau aaaugaacua aaagcauuag gauuauacgg caacaucacc      720

agugcaacug aaugggcauc agaugucggg auauacuauu uaucaaaauu cggacucuau      780

agcacaaacc gaaacgacau aguacaauca cuagagaaag caguagacau guacaaauac      840

gggaaaauag cauuuguagc cauggaacga auuacauggg acuacgaugg cauagguagc      900

aauggaaaga aaguagauca cgauaaauuc cuugacgacg cagaaaaaca cuaucuuccu      960

aaaacauaca cuuuugauaa cgguaccuuc auaauacgag ccggugauaa aguaagcgaa     1020

gagaaaauaa aaaggcuaua uugggcaagc agagaaguca aaagccaauu ucauagagua     1080

guaggaaaug acaaagcacu agaaguugga aacgcugacg auguucuaac aaugaaaauc     1140

uucaacucac cugaagaaua caaauucaac acaaacauaa auggaguaag uaccgacaac     1200

ggaggauuau auauagaacc cagggggacg uuuuauaccu acgagagaac cccucaacaa     1260

ucuauauuuu ccuuagaaga auuauuucga caugaauaca cacacuauuu acaagcacga     1320

uauuugguag auggacuaug gggacaagga ccauuuuaug agaaaaacag acuuacgugg     1380

uucgacgaag gaacggcaga guucuuugca ggaaguacaa gaacaagugg aguauuacca     1440

agaaaaucaa uacuagguua cuuagcaaaa gacaaaguag aucacagaua cagccuaaag     1500

aaaacacuga auagcgguua ugaugacagu gauuggaugu ucuauaauua cggauucgca     1560

guagcucacu aucuauauga aaaagauaug ccaacauuca ucaaaaugaa uaaagcaaua     1620

cuuaacaccg acguuaaauc auaugacgaa auaauaaaga aauuaaguga cgacgcaaac     1680

aaaaauaccg aauaccaaaa ccacauccaa gaacuagcag acaaauauca aggugcagga     1740

auaccauuag uaucagacga cuaccucaaa gaccauggau acaagaaagc guccgaagua     1800

uacucagaaa uaaguaaagc agcaucauug acuaauacuu caguaacagc agaaaaauca     1860

caauacuuua acacauucac acuucgcgga acauauacgg gagaaaccuc aaaaggugaa     1920

uuuaaagauu gggacgaaau gaguaaaaag cucgacggca cucuagaauc auuggcuaaa     1980

aacuccuggu caggauauaa aacacuaaca gccuacuuca ccaauuacag agucaccuca     2040

gauaauaaag uacaauauga cguaguauuu cauggagucu uaacagacaa cgcugauaua     2100

aguaacaaua aagcgccuau agcgaaagua acaggaccau caacgggagc aguaggaaga     2160

aauauugagu ucucaggaaa ggauagcaaa gacgaagacg gaaaaauugu aucuuaugau     2220

ugggauuucg gagauggagc aaccucaaga gggaaaaaca gugugcaugc cuacaagaaa     2280

gcaggaacuu auaauguaac acuaaaagug acagaugaca aaggagcgac agcaacagag     2340

agcuucacga uugaaauuaa aaacgaagau acuacaacac ccauaacaaa agaaauggaa     2400

ccaaaugaug acauaaaaga agcaaacgga ccgauagugg aaggcguaac gguaaaagga     2460

gacuuaaaug gaagugauga cgccgacaca uuuuacuuug auguuaaaga agacggugau     2520

gucacaauag aauuacccua cucugguagu uccaacuuca cuugguuagu auacaaagaa     2580

ggagaugauc aaaaucauau agcauccgga auagacaaaa acaauagcaa aguaggcaca     2640

uuuaaaucca caaaaggacg ucauuauguu uucauuuaca aacacgauag ugcaaguaac     2700

auaaguuauu cucuaaauau aaaaggacua gguaaugaaa aacuaaaaga aaaagaaaac     2760

aacgauagca gugacaaagc uacuguuauc ccaaacuuca acaccacaau gcaaggcagc     2820

uuacucggag acgauucacg agauuauuac agcuucgaag uaaaagaaga gggggaagua     2880

aacauagaac uagauaagaa agacgaauuu ggaguaacau ggacacuaca cccggaaucg     2940

aacauaaaug acagaaucac auauggacaa guagacggaa acaaaguauc aaauaaaguc     3000

aaacuaagac cuggcaaaua uuaccuauua guguauaaau auucaggauc agguaauuac     3060

gaacugagag ucaauaaaua a                                               3081


<210>  706
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  706
augaaguggg uaacuuucau aagucuucuu uuccuuuucu cuucagcaua cucgaugaag       60

aaaaacauac uaaaaauacu cauggauucc uauagcaaag aaaguaaaau acaaacagua      120

cggagaguua caucaguaag ucuauuagca guauaccuaa caaugaauac aagcuccuua      180

guauuagcaa agccaaucga aaacacaaac gauacgucaa uuaaaaacgu agaaaaauua      240

cgaaacgcac cuaaugaaga aaacucaaag aaagucgaag acagcaaaaa cgauaaaguc      300

gagcacguga aaaauauaga agaagcaaaa guagaacaag uagccccaga aguaaaaagu      360

aaaucaacuc uaagaucugc uucacgcaga cgacguaaac gaauagccaa cacaaauuca      420

gaaaaauaug auuucgaaua ccuaaacggg uuaucauaca cagagcuaac gaaucuaauc      480

aaaaacauaa aauggaacca aauaaauggc cuauuuaauu auagcacagg aucccaaaaa      540

uucuucggcg acaaaaaucg aguacaagca auaauuaaug cacuacagga aucuggcaga      600

acauauacug cuaaugacau gaaaggaaua gaaacauuua cagaaguacu cagagcagga      660

uuuuauuuag guuauuauaa ugacggcuua aguuaccuaa augauagaaa cuuucaagau      720

aaaugcauac cugcaaugau cgcaauacag aaaaacccaa acuuuaaacu agggacagcg      780

guacaagacg aaguaauaac cagcuuagga aaacucaucg gaaacgcuuc ugcaaacgcg      840

gaaguuguaa acaacugcgu accaguacua aaacaauucc gagaaaaccu aaaucaauac      900

gcuccagauu auguaaaagg aacggcugua aacgaauuaa uaaaagguau cgaauuugau      960

uucagcggcg cagccuauga aaaggacguc aaaacgaugc caugguaugg aaaaauagac     1020

ccauucauaa augaacugaa agcacucgga cuuuacggua auauaacaag ugcuacagaa     1080

ugggcaucag acguaggaau auauuauuua ucaaaauucg gauuauacuc aacaaauaga     1140

aaugacauag uacaaagucu agaaaaagcg gucgacaugu acaaauaugg caaaauagca     1200

uuuguagcua uggaacgcau aacaugggac uaugauggaa uagguucuaa cgguaagaaa     1260

guugaucaug auaaauucuu agaugacgca gaaaaacacu acuuaccaaa aacauauaca     1320

uucgacaacg gcaccuuuau aauacgugcc ggagacaaag uuagugaaga gaaaauuaaa     1380

cgacuauacu gggcuucgag agaaguaaaa ucucaauuuc acagagucgu gggaaacgau     1440

aaagcacuag aaguuggaaa cgcagaugau guccucacaa ugaaaaucuu uaauuccccg     1500

gaagaauaca aauuuaauac gaauaucaac ggcgugucaa cugauaaugg aggacuguau     1560

auagaaccac gaggaacauu cuacacuuau gaaagaaccc cgcaacaaag cauuuucucc     1620

cuagaagaac uauucaggca ugaauauaca cauuaccucc aagccagaua ccuaguugau     1680

ggacuauggg gacaaggacc guuuuacgag aaaaaucgau uaaccugguu ugaugaagga     1740

acggcagagu ucuuugcagg aucaacaaga acaagcggag uacuaccaag aaaauccaua     1800

cuagguuacu uagcaaaaga uaaaguugac cacagauaua guuuaaagaa aacccucaac     1860

agugguuacg augauucgga uuggauguuu uacaacuacg gauucgcagu ugcgcacuac     1920

uuauacgaaa aagauaugcc aacguucaua aaaaugaaca aagcaauacu aaauacugau     1980

gucaaaagcu acgaugaaau aauaaagaaa cuaagugacg acgccaauaa aaauacagaa     2040

uaccaaaacc auauacaaga acuagcugac aaauaccaag gugcgggaau accucuagua     2100

agugacgacu aucuaaaaga ucauggauau aagaaagcau cagaaguuua cucugaaauc     2160

agcaaagccg caucauuaac aaacaccuca guaacagcug aaaaaucaca auauuucaac     2220

acauucacac uaagggguac auauacaggc gaaaccagua aaggagaauu uaaagauugg     2280

gacgaaauga gcaagaaauu agauggaacu cuagaaucuu uagccaaaaa cucuugguca     2340

ggauacaaaa cauuaacggc auauuucacg aacuauagag uuacaaguga uaauaaagug     2400

caauaugacg uaguauuuca cggaguccuc acagauaacg ccgauauuuc aaauaauaaa     2460

gcuccgauag cuaaaguaac cgguccaucc acaggagcag uaggcagaaa cauugaguuc     2520

ucugguaaag auaguaaaga ugaagaugga aaaauagucu cauacgacug ggauuucgga     2580

gauggagcaa caucaagagg gaaaaacuca guacaugccu auaagaaagc gggaaccuau     2640

aacguaaccc uaaaagucac agaugacaag ggagcaacgg cuacagaaag uuuuacaauc     2700

gaaauuaaaa augaagacac aacaacacca auaacgaagg aaauggaacc aaacgacgac     2760

aucaaagaag cuaacggacc aauaguugaa ggaguaacag uuaaaggaga uuuaaacgga     2820

ucagaugaug cggacacuuu uuacuucgau gucaaagaag auggagacgu caccauugaa     2880

uuaccuuauu caggaagcag uaacuucacc ugguuaguau auaaagaagg agacgaucaa     2940

aaccacaucg cuagcggcau agauaaaaau aauucaaagg uuggaaccuu uaagucaaca     3000

aaaggaagac acuauguauu uaucuacaaa caugauuccg ccucaaacau auccuauagc     3060

cugaauauca aaggccuagg aaacgaaaaa uuaaaagaaa aagaaaauaa cgacagcuca     3120

gauaaagcaa caguaauucc uaacuuuaac acuacaaugc aagguagccu auugggugac     3180

gauaguagag acuauuacag cuuugaaguc aaagaagaag gagaaguuaa uauagaacua     3240

gacaagaaag augaguuugg aguaaccugg acauugcacc cugaauccaa uauaaaugac     3300

agaauuacuu auggccaagu cgacggaaau aaagucucaa acaaagugaa acuaagaccg     3360

gguaaauauu accuuuuggu guacaaauau aguggcucag gaaacuauga auuaaggguc     3420

aacaaauga                                                             3429


<210>  707
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  707
augaacuuuc ucaaaauaau acugaaccgu ggcaaaacaa ugaaaagaaa augccuaagu       60

aaaagacuca ugcuggccau cacaauggcu acaauauuca ccgucaacag caccuuaccu      120

auuuaugcag ccguagacaa aaauaacgcu acugccgccg uacaaaauga aagcaaaaga      180

uacacugucu cguaucuuaa aacacuaaau uacuacgacc uaguagauuu auuaguaaaa      240

acagaaauag aaaaccuacc ugaucucuuu caauacucau cagaugccaa agaauuuuac      300

ggaaacaaaa cacgaauguc uuuuauaaug gaugaaauag gccgcagagc uccacaauac      360

accgaaaucg accacaaagg aauaccaaca uuaguggaag ugguaagagc aggauuuuau      420

uuaggcuucc acaacaaaga acuaaacgaa auaaauaaaa gauccuucaa ggaaagggua      480

auacccucaa uauuagcaau acagaaaaac cccaauuuca aacuaggaac agaagugcaa      540

gacaaaaucg ucagcgcaac gggacuucua gccgguaacg aaacugcucc accagaagua      600

guaaacaacu ucaccccaau ccuacaagac uguauuaaaa acauagacag auaugcauua      660

gacgaucuaa agucaaaggc uuuauuuaac gucuuagcug caccuacuua cgacauaaca      720

gaauaccuca gggcaacaaa agaaaaaccg gaaaauacac cuugguacgg aaaaauagau      780

ggcuucauaa acgaacuaaa gaaauuagcc uuauacggaa aaauuaacga uaauaacucu      840

uggauaauag auaaugguau uuaccacaua gcuccguuag ggaaacugca uaguaacaau      900

aaaaucggaa uagaaacauu aaccgaaguc augaaaguau acccauauuu aucaaugcaa      960

cacuuacaau ccgccgacca aaucaaaaga cacuacgaca gcaaagaugc agaaggaaau     1020

aaaauaccau uagauaaauu caagaaagaa ggaaaagaaa aauacugccc aaaaaccuau     1080

acuuucgacg auggaaaagu aauaauaaaa gcuggagcaa gagucgaaga agaaaaagua     1140

aaacgacucu acugggcauc aaaagaaguc aacucacaau ucuucagagu cuauggcaua     1200

gauaaaccgc uagaagaggg aaaccccgau gacauccuaa caaugguaau auacaauuca     1260

ccagaagagu auaaacuaaa uagcguauua uacggauacg acacaaauaa cggcggaaug     1320

uacaucgaac cugaaggaac cuucuucacc uaugagcgag aagcccaaga aaguacauac     1380

acccuggaag aacuauucag acaugaauac acacauuacc uacaaggacg auacgccgug     1440

ccaggacaau gggggcgaac gaaauuauac gacaacgaca gacucacaug guaugaagaa     1500

gguggagcag aauuauucgc aggcaguacc cguacaucag guauccuacc aagaaaaucu     1560

aucgucagua acauacacaa cacaacuagg aauaaucgau acaaauuauc agacacagua     1620

cauuccaaau acggggccuc cuucgaauuu uacaacuacg cgugcauguu uauggauuau     1680

auguauaaca aagauauggg uauucuaaac aaauuaaacg accuagccaa gaauaaugac     1740

guggacggau acgacaacua uauuagggac cuaucaucaa auuaugcauu aaacgacaaa     1800

uaccaagacc acaugcaaga gaggauagau aauuacgaaa accuaacagu accauuuguc     1860

gcagacgauu auuuagugcg acaugcauac aaaaauccaa acgaaaucua cagugagauu     1920

ucagagguag caaaacucaa ggaugcgaaa uccgaaguca agaaaaguca auacuucagu     1980

acauucacgc uaagaggauc auauacagga ggagccucaa aaggaaaauu agaagaccaa     2040

aaagcaauga auaaauucau agacgauuca uuaaagaaac uagauaccua caguuggagu     2100

ggcuauaaaa cacucacugc auauuucaca aauuacaaag uagacucauc uaauagggua     2160

accuacgaug uaguauucca cggauaccuc ccaaaugaag gcgacagcaa aaacucucuc     2220

ccauacggaa aaauaaacgg gacauacaaa gguacugaaa aagagaaaau caaauucagc     2280

agcgaaggau ccuucgaccc agacggaaaa auuguuaguu augaauggga cuucggagau     2340

ggaaacaaaa guaaugaaga aaacccagaa cauuccuaug acaaagucgg gacuuacacc     2400

guaaaauuaa aaguuacaga ugauaaaggc gaauccagug uaucaacaac aacagccgaa     2460

aucaaagacu uaagcgaaaa uaaacuucca guaauauaua ugcacguacc aaaaucugga     2520

gcacuuaacc aaaaaguagu auucuacggu aaagguacau acgauccaga cggaucaaua     2580

gcuggguauc aaugggacuu uggagacggu ucagauuucu caucagaaca aaaucccucc     2640

cacguauaca caaagaaagg ugaauacaca gugacacuaa gagucaugga uagcagcggc     2700

caaaugucag agaaaacaau gaaaaucaaa auaacugauc ccguauaucc aauaggcaca     2760

gaaaaagaac caaacaacag caaagaaaca gccagcggac caauaguacc aggcauaccc     2820

gucaguggaa cuauagaaaa uacauccgac caagacuacu uuuacuucga uguaauaacc     2880

ccuggagaag uaaaaauaga cauaaacaaa uuagguuaug ggggcgcaac auggguagug     2940

uacgaugaaa auaauaacgc aguaaguuau gcuacagacg acggccaaaa ucuauccgga     3000

aaauucaaag cagacaaacc aggcagauac uauauucauc uauauauguu uaacgguagc     3060

uacaugccuu acaggaucaa cauagaagga agcguaggua gauag                     3105


<210>  708
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  708
augaaacgua aaugccuuuc aaaacgucua auguuggcaa uuacuauggc aacaauauuu       60

acaguuaauu ccacacuacc aauauaugca gcuguagaca aaaacaaugc cacagccgca      120

guacaaaaug aauccaaaag guacacuguc aguuaucuaa aaacucuuaa cuauuacgac      180

cuaguugacc uauuaguaaa aacagaaaua gaaaaccuac cagacuuauu ccaauacuca      240

ucugaugcua aagaauuuua cggaaauaaa acccgcauga guuuuaucau ggaugaaaua      300

ggaagacgag cgccucaaua uacugaaauc gaucacaaag gaauaccgac gcuaguagaa      360

guuguaagag ccgguuuuua cuuaggcuuu cacaacaaag aacuaaacga aauaaauaaa      420

cgaucauuua aagagagagu aauacccagc auccuugcca uacaaaagaa uccaaacuuc      480

aaauuaggaa cagagguaca agacaaaaua guauccgcca caggccuauu agcaggaaau      540

gagacagcac ccccugaggu agugaacaau uucacaccaa uauuacaaga uugcauuaaa      600

aauauagaua gauaugcucu agaugaucua aaaucaaaag cacuauucaa cguacuagca      660

gcacccacau acgauauaac agaauacuua cgagcgacca aagaaaaacc agaaaacaca      720

ccaugguacg gaaaaauaga cggcuuuaua aaugaguuaa agaaauuagc auuauauggu      780

aaaauaaaug auaauaacag cuggauuaua gacaacggga uauaucauau agcaccccua      840

ggaaaacuac acucaaacaa uaaaauagga auagaaacau uaaccgaagu caugaaaguu      900

uauccuuacu uauccaugca acacuuacaa ucagcagauc aaauaaaaag acauuaugau      960

ucaaaagacg cagaagguaa caaaauaccc cuagacaaau uuaagaaaga aggaaaagaa     1020

aaauauugcc caaaaacaua cacauuugac gacgggaaag uaaucauaaa agcaggagcg     1080

agagucgaag aagaaaaagu aaaaagacuc uacugggcau cuaaagaagu aaacucccaa     1140

uucuucaggg uauauggaau agacaaacca uuagaagaag gaaaucccga ugacauuuug     1200

acaaugguaa ucuauaauag uccggaagaa uauaaacuga acagugucuu auacggauau     1260

gauaccaaca acgguggaau guauauagaa ccagagggaa ccuucuucac cuaugaaagg     1320

gaagcccaag aaucaacaua cacucucgag gaacuauuua ggcacgaaua uacacacuau     1380

uuacaaggac gauacgcagu accaggacaa uggggcagga caaaacuuua cgauaacgac     1440

agacuaacuu gguaugaaga agguggcgcc gaacuauucg ccgguucaac ucgcacaagc     1500

ggaauauugc cacgaaaauc aaucguaucu aacauacaca acacaacaag aaauaaccgu     1560

uacaaacuau cagauacagu ucacuccaaa uacggagcaa guuuugaauu uuacaacuac     1620

gccuguaugu uuauggacua cauguauaau aaagauaugg gcauacuaaa uaaacugaac     1680

gauuuagcua aaaacaauga cguagacggc uacgacaacu acauaagaga uuuaaguucc     1740

aacuaugcac uaaaugauaa auaucaagau cacaugcaag aaagaauaga uaacuaugaa     1800

aauuuaacag uaccuuuugu ggcagacgau uaccuuguuc gacacgcaua uaaaaacccc     1860

aaugagauau auucagaaau uucagaagua gcaaaauuaa aagaugcaaa aagcgaagua     1920

aagaaaagcc aauacuucuc cacauuuacc cuccgaggau cauacaccgg cggagccucc     1980

aaaggaaaac uagaagacca aaaagcuaug aacaaauuca uagaugacuc ccuaaagaaa     2040

uuagacacau auucaugguc cggauacaaa acccuaacgg cuuacuucac aaauuacaaa     2100

gucgacuccu caaauagggu uacauacgac gucguauuuc acggauaucu ccccaaugag     2160

ggagacagua aaaauucccu accauacggg aaaauaaacg gaacauauaa agggacagaa     2220

aaagagaaaa uaaaauucuc gucugaagga ucuuuugacc ccgacgggaa aauuguguca     2280

uaugaauggg auuuuggaga uggaaauaaa ucaaaugaag aaaacccaga acacagcuau     2340

gacaaaguag gcacauacac cguaaaauua aaaguaacag acgacaaagg agaaucauca     2400

guauccacca ccacagcaga aauuaaagau cuaucugaaa acaaacuccc aguaaucuau     2460

augcacguac cuaaaagugg cgcucucaau caaaaaguag uauuuuacgg aaaaggaaca     2520

uaugacccag acggaagcau agcaggguau caaugggauu ucggagaugg aucugauuuu     2580

ucuucagaac aaaacccauc gcacguauac accaagaaag gagaauauac aguaacacua     2640

agaguuaugg auucaucugg acaaaugucu gagaaaacua ugaaaauaaa aauaacagac     2700

ccaguuuauc caauaggcac agaaaaagaa ccaaacaaca guaaagaaac agcaucagga     2760

ccaaucgucc cgggcauacc aguaagugga acaauagaaa auacaagcga ccaagauuac     2820

uucuacuucg auguaauaac accaggcgaa guuaaaauug acauaaacaa acucggauau     2880

ggaggagcaa cauggguagu auaugaugaa aacaauaaug ccguaucuua cgccacagac     2940

gauggacaaa accuaagugg aaaauuuaaa gcugauaaac ccggacgcua cuacauacac     3000

cuguauaugu uuaacgguuc auacaugcca uacaggauaa acauagaagg gaguguggga     3060

agauaa                                                                3066


<210>  709
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  709
augaaauggg uuacuuuuau aucauuacua uuccuauucu caucagcaua cagcguacag       60

aacgaaucaa aaagauacac aguaaguuac uuaaaaacgu uaaacuacua cgaccuagua      120

gauuuauuag ucaaaaccga aauugaaaau uuacccgacc uuuuccaaua cucuuccgau      180

gcaaaagaau uuuacggcaa uaaaacacga augagcuuca uaauggauga aaucgguaga      240

cgagcucccc aauacacaga aauagaccac aaaggaaucc cuacauuagu ugaaguaguu      300

agagcaggau ucuaccuagg uuuucauaac aaggaauuaa augaaauaaa uaaacgauca      360

uucaaagaac gaguaauacc aucaauacuu gcaauacaga aaaacccaaa cuuuaaacuu      420

ggaacugaag uucaagacaa aauaguguca gcaacaggac uccuagcugg caaugaaaca      480

gcuccaccag aaguaguaaa caacuuuaca ccaauauuac aagauugcau uaaaaauaua      540

gaccgcuacg cuuuagauga ucuaaaaagu aaagcacuau uuaacguacu ggcagcaccu      600

acuuacgaca uaaccgaaua ccuacgagca acaaaagaaa aaccugaaaa cacccccugg      660

uacggaaaaa uagacggauu uaucaacgaa cuaaagaaau uagcacuuua uggaaaaauu      720

aacgauaaua auuccuggau caucgacaau ggcauauacc auauagcucc acuaggaaaa      780

uuacacucaa acaacaaaau aggaauagaa acacuaacgg agguaaugaa aguauaccca      840

uaucuaucaa ugcaacaccu acaaucagcc gaucaaauaa aaagacauua ugacucaaaa      900

gaugcagaag gcaacaaaau accacuagac aaauucaaga aagaaggaaa agaaaaauau      960

uguccgaaaa cauacaccuu ugaugaugga aaaguaauua uaaaagcugg agcaagaguc     1020

gaagaagaaa aaguuaaacg auuauauugg gcaucaaaag aaguaaauag ucaauuuuuc     1080

cgcgucuaug gaauagauaa accccuugag gaaggaaauc cagacgacau ccuaacaaug     1140

guaauauaua auucaccuga agaauacaaa uuaaauucag uacuauaugg auacgacaca     1200

aacaacggag gaauguacau agaaccagaa gguacauucu uuacauauga gagagaagca     1260

caagaaagca cauacacucu agaagaacua uucagacacg aguacaccca cuaccuacaa     1320

ggucgauaug cuguaccagg acaaugggga aggacaaaac uauacgauaa ugacagacua     1380

accugguacg aagaaggagg agccgaacua uucgcaggaa gcacacguac aucagguaua     1440

cuaccaagaa aauccauagu cagcaacaua cauaacacga cacguaacaa cagauacaaa     1500

uuaagugaca caguucauag caaauaugga gcuucauuug aguuuuauaa cuacgcaugu     1560

auguucaugg auuacaugua caacaaagac augggaaucu uaaauaaacu aaacgauuua     1620

gcuaaaaaua augauguaga uggauacgac aacuauauac gcgauuuaag caguaacuac     1680

gcacuaaacg auaaauacca agaucacaug caagaaagga uagacaacua cgaaaauuua     1740

acagucccau ucgucgcaga cgauuaccua gucagacacg ccuauaaaaa uccuaacgaa     1800

auauacucag agauuagcga ggucgcaaaa uuaaaagacg caaaaaguga aguaaagaaa     1860

agucaauauu ucaguacauu uaccuuaaga ggcucauaua caggcggagc aaguaaagga     1920

aaauuagaag aucaaaaagc aaugaauaaa uucauugaug acagccuaaa gaaauuagac     1980

acauacucau ggucgggcua caaaacccuu accgcuuacu uuacaaacua uaaagucgac     2040

aguucaaaca gggucacaua cgacguugua uuccacggcu acuuaccaaa ugaaggagac     2100

aguaaaaacu cccuaccaua cggaaaaaua aauggaacgu auaaaggaac agaaaaagag     2160

aaaauaaaau ucucaucaga aggaucauuc gacccggacg gaaaaauugu uuccuacgaa     2220

ugggacuucg gggacgguaa caaaucgaac gaagaaaauc cugaacauuc auaugauaaa     2280

guaggaacau acacaguaaa acuaaaaguc acagaugaca aaggagaauc guccguaucu     2340

accacaacag cggaaauaaa agauuuauca gaaaauaaac uacccguuau uuacaugcau     2400

gucccaaaaa gcggagcauu aaaccaaaaa guaguauuuu acggaaaagg cacauaugau     2460

ccagacggau caauugccgg uuaucaaugg gacuucggag acggaagcga cuucaguagu     2520

gaacaaaacc ccucccaugu auacacaaag aaaggugaau acacagucac cuuaagagua     2580

auggacucau caggacagau gagugagaaa acaaugaaaa uaaaaauaac cgaccccguc     2640

uauccaauag gaaccgaaaa agaaccaaau aauucaaaag aaacagcauc aggaccaaua     2700

guacccggca ucccaguauc uggcaccauc gaaaacaccu cugaucaaga cuacuucuac     2760

uucgacguaa uaacaccagg ugaaguaaaa auugauauca auaaacuagg auacggcgga     2820

gcaacauggg uaguuuacga cgaaaacaac aacgcaguua gcuacgcuac agaugacgga     2880

caaaaccuaa gugggaaauu uaaagcagac aaaccuggaa gauauuauau ccaucucuac     2940

auguucaacg guucuuauau gccauauaga auaaacauag aaggcucagu aggaagauaa     3000


<210>  710
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  710
augaaauggg uuacauucau cagcuuacua uuccuauuca guagcgccua cagcaugaaa       60

agaaaauguu uauccaaaag acuaaugcua gcuaucacaa uggcuacaau uuucacagug      120

aacucuacau uaccaauaua cgcugcaguu gauaaaaaca acgcaacagc cgcuagaaga      180

agaagaaaac gaguacaaaa cgaaagcaaa agauacaccg ucucuuacuu aaaaacacua      240

aauuacuacg aucugguaga ccuucuagua aaaacugaaa uagaaaaucu accagacuua      300

uuccaauauu caagcgacgc aaaagaauuu uacggaaaca agacaagaau gaguuuuauu      360

auggaugaaa uuggacguag agcaccccaa uacaccgaaa uagaucacaa aggcauaccc      420

accuuagugg aaguuguaag agccggguuc uacuuaggau uucauaauaa agaauuaaau      480

gaaauaaaua aacgauccuu caaagaaaga gucauaccaa gcauucucgc aauucagaaa      540

aacccaaauu ucaaacuagg aaccgaagua caagauaaaa uuguaucagc aaccggauua      600

uuagcuggua acgaaacagc ucccccugaa guaguaaaua acuuuacccc cauauuacaa      660

gauugcauua aaaauauaga cagauacgcc uuagacgacc uaaaaucaaa agcacuauuc      720

aauguccucg cugcuccaac auaugacaua acagaauacc uuagagcgac uaaggaaaaa      780

cccgaaaaca ccccauggua ugguaaaaua gaugguuuca uaaacgaacu aaagaaacuc      840

gcacuauacg gaaaaauaaa cgacaacaau agcuggauaa uagacaaugg aauauaucau      900

auagcaccau uaggaaaacu acauucaaac aauaaaaucg gaauagaaac auuaacagaa      960

guaaugaaag uauaucccua uuuaagcaug caacaucuac agucugcgga ccaaauaaaa     1020

cgucauuacg acucuaaaga cgcagaagga aacaaaauuc cacuagacaa auuuaagaaa     1080

gaagggaaag aaaaauacug cccaaaaacc uacacuuuug augauggaaa aguaauuaua     1140

aaagcuggag cacgcguaga agaagaaaaa guaaaacgau uauacugggc caguaaagaa     1200

gugaauaguc aauucuucag agucuaugga auugacaaac cucuagaaga aggcaaccca     1260

gacgauauac uaaccauggu uauauauaau ucuccagaag aauacaaacu aaauucagua     1320

uuauacggau augauaccaa caacggaggg auguacauag aaccugaagg uacuuucuuu     1380

acauacgaaa gagaagcaca agaaagcaca uauaccuuag aggaacuauu uagacacgaa     1440

uauacacacu accugcaagg aagauaugcu gugccaggac aauggggacg uacuaaacua     1500

uacgacaacg auagacuaac augguaugaa gaaggaggag cagaacucuu ugcuggcucc     1560

accagaacaa guggaaucuu accaagaaaa aguauaguau caaacauaca uaacacaaca     1620

agaaauaaca gauacaaacu cagcgacaca guacacucaa aauacggagc uagcuucgaa     1680

uuuuauaauu acgcaugcau guucauggac uacauguaca acaaagauau gggaaucuua     1740

aacaaacuaa augaucuagc gaaaaauaau gauguugaug guuacgacaa cuauauccgu     1800

gaucucucau caaacuacgc acugaacgac aaauaccaag aucauaugca agaacguaua     1860

gauaauuaug aaaauuuaac uguacccuuc guagcagaug auuacuuggu uaggcaugca     1920

uacaaaaauc cuaaugaaau auacucagaa auaucugaag uagccaaacu aaaagaugca     1980

aaaagugaag uuaagaaaag ccaauauuuu uccacauuua cauuacgagg auccuauacu     2040

ggaggggcca guaaagguaa acuagaagac caaaaagcaa ugaacaaauu caucgaugau     2100

ucccuaaaga aauuagauac auauaguugg ucaggcuaca aaacacuaac agccuauuuu     2160

acaaauuaca aaguagauuc aagcaauaga guuacauacg acguaguauu ccaugguuau     2220

uuaccaaaug aaggcgacag uaaaaauuca uuaccauacg gaaaaauaaa uggaacauau     2280

aaaggaacgg aaaaagagaa aauaaaauuc uccucugaag gauccuuuga cccagacgga     2340

aaaaucguua gcuacgaaug ggacuucggu gaugguaaca aaucaaacga agaaaacccu     2400

gaacacagcu acgacaaagu aggaaccuac acagucaaac ucaaaguaac agaugauaaa     2460

ggugaaucuu cuguuucuac gacaacagca gaaaucaaag auuuauccga aaacaaacuc     2520

ccagucauau auaugcacgu accaaaauca ggugcacuua aucaaaaggu uguauuuuau     2580

ggaaaaggua cauaugaucc cgacggauca aucgcaggau accaauggga cuucggagac     2640

gggucagauu ucuccucuga acaaaaccca agccacguau acaccaagaa aggagaauau     2700

accguaaccu uacgagucau ggauaguuca ggucaaaugu cagagaaaac aaugaaaauc     2760

aaaauaacug auccaguaua cccaaucgga acagaaaaag aaccaaauaa uagcaaagaa     2820

acagcaagug gacccaucgu gccaggcauc ccaguaucgg gcacaauaga aaauacgagc     2880

gaccaagacu auuucuacuu ugacgucaua acaccaggag aaguaaaaau cgauauaaau     2940

aaacuaggau acggaggagc cacauggguc gucuacgaug aaaacaacaa ugccgugagc     3000

uaugcaacag acgauggaca gaaucuuucu gggaaauuca aagcagauaa accaggacga     3060

uacuauauac acuuauacau guuuaauggu aguuacaugc cauaccgaau aaacauugaa     3120

ggaagcguug gaagauga                                                   3138


<210>  711
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  711
auggguaccu ggauauuauu cgcaugccua cuaggcgcag cauucgccau gccauuacca       60

ccacacccag gacacccagg auacaucaac uucucauacg aaguacuaac accacuaaaa      120

ugguaccaau caauaagacc accauaccca ucauacggau acgaaccaau ggguggaugg      180

cuacaccacc aaauaauacc aguacuauca caacaacacc caccaacaca cacacuacaa      240

ccacaccauc acauaccagu aguaccagca caacaaccag uaauaccaca acaaccaaug      300

augccaguac caggacaaca cuccaugaca ccaauacaac aucaccaacc aaaccuacca      360

cccccagcac aacaaccaua ccaaccacaa ccaguacaac cacaaccaca ccaaccaaug      420

caaccacaac caccaguaca ccccaugcaa ccacucccac cacaaccacc acuaccacca      480

auguucccaa ugcaacccuu accaccaaug cuaccagacc uaacacuaga agcauggccc      540

ucaacagaca aaacaaaaag agaagaaguc gacuaa                                576


<210>  712
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  712
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aucaauaaga ccaccauacc caucauacgg auacgaacca      120

augggaggau gguaa                                                       135


<210>  713
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  713
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aucaauaaga ccaccaccaa ugcuaccaga ccuaacacua      120

gaagcauggc caucaacaga caaaacaaaa agagaagaag uagacuaa                   168


<210>  714
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  714
auggcaguaa uggcaccaag aacacuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauacau aaacuucuca      120

uacgaaguac uaacaccacu aaaaugguac caaucaauaa gaccaccaua cccaucauac      180

ggauacgaac caaugggagg augguaa                                          207


<210>  715
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  715
auggcaguaa uggcaccaag aacauuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauacau aaacuucuca      120

uacgaaguac uaacaccacu aaaaugguac caaucaauaa gaccaccacc aaugcuacca      180

gaccuaacac uagaagcaug gccaucaaca gacaaaacaa aaagagaaga aguagacuaa      240


<210>  716
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  716
augggaacau ggauacuauu cgcaugcuua guaggagcag cauucgccau gccacuacca       60

ccacaccccg gccacccagg auacauaaac uucucauacg aaguauuaac accacuaaaa      120

ugguaccaau caaugauacg cccaccauac uccucauacg gauacgaacc aaugggcggc      180

ugguuacacc aucaaauaau accaguagua ucccaacaac acccacuaac acacacacua      240

caaucacacc accacauacc aguaguacca gcacaacaac cacgaguacg ccaacaagca      300

cuaaugccag uaccaggaca acaaucaaug acaccaacac aacaccacca accaaaccua      360

ccauuaccag cacaacaacc auuccaacca caaccaguac aaccccaacc acaccaacca      420

augcaaccac aaccaccagu acaaccaaug caaccacucc uaccccaacc accacuacca      480

ccaauguucc cacuaagacc acuaccacca auacuaccag accuacaccu agaagcaugg      540

ccagcaacag acaaaacaaa acaagaagaa guagacuaa                             579


<210>  717
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  717
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aucaaugaua agaccaccau acucaucaua cggauacgaa      120

ccaaugggag gaugguaa                                                    138


<210>  718
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  718
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguauua       60

acaccacuaa aaugguacca aucaaugaua agaccaccac caauacuacc agaccuacac      120

cuagaagcau ggccagcaac agacaaaaca aaacaagaag aaguagacua a               171


<210>  719
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  719
auggcaguaa uggcaccaag aacauuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacau ccaggacacc caggauauau aaauuucuca      120

uacgaaguau uaacaccacu aaaaugguau caaucaauga uaagaccacc auacagcuca      180

uacggauacg aaccaauggg aggaugguaa                                       210


<210>  720
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  720
auggcaguaa uggcaccaag aacacuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauacau aaacuucuca      120

uacgaaguac uaacaccacu aaaaugguau caaucaauga uaagaccacc accaauacua      180

ccagaccuac accuagaagc auggccagca acagacaaaa caaaacaaga agaaguagac      240

uaa                                                                    243


<210>  721
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  721
augggaaccu ggauauuauu cgcaugccua cuaggagccg cauucuccau gccacuacca       60

ccacacccag gacacccagg auacauaaac uucucauacg aaguauuaac cccauuaaaa      120

ugguaucaaa acaugauaag acacccauac acaucauacg gauacgaacc aaugggagga      180

uggcuacacc accaaauaau accaguagua ucccaacaaa caccacaauc acacgcacua      240

caaccacacc accauauacc aaugguacca gcacaacaac caggaauacc acaacaacca      300

augaugccac uaccaggaca acacucaaug acaccaacac aacaccacca accaaaccua      360

ccacuaccag cccaacaacc auuccaacca caaccaguac aaccacaacc acaccaacca      420

cuacaacccc aauccccaau gcacccaaua caaccacuac uaccacaacc accacuaccc      480

ccaauguucu caaugcaauc acuacuacca gaccuaccac uagaagcaug gccagccaca      540

gacaaaacaa aaagagaaga aguagacuaa                                       570


<210>  722
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  722
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aaauaugaua agacacccau acacaucaua cggauacgaa      120

ccaaugggag gaugguaa                                                    138


<210>  723
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  723
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aaacaugaua agacacccau cacuacuacc agaccuacca      120

cuagaagcau ggccagcaac agacaaaaca aaaagagaag aaguagacua a               171


<210>  724
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  724
auggcaguaa uggcaccaag aacauuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacau ccaggacacc caggauauau aaauuucuca      120

uacgaaguau uaacaccacu aaaaugguau caaaauauga uaagacaucc auauacauca      180

uacggauacg aaccaauggg aggaugguaa                                       210


<210>  725
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  725
auggcaguaa uggcaccaag aacacuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauacau aaacuucuca      120

uacgaaguac uaacaccacu aaaaugguac caaaacauga uaagacaccc aucacuacua      180

ccagaccuac cacuagaagc auggccagca acagacaaaa caaaaagaga agaaguagac      240

uaa                                                                    243


<210>  726
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  726
augggaacau ggauacuauu cgcaugccua cucggugcag cauucucaau gccacuacca       60

ccacacccag gacacccagg auacauaaac uucucauaca uacgacaccc auacacauca      120

uacggauacg aaccaauggg aggauggcua caccaccaaa uaauacccgu aguaucucaa      180

caaacaccac aaucacacgc acuacaacca caccaccaca uaccaauggu accagcacaa      240

caaccaggaa uaccacaaca accaaugaug ccauuaccag gacaacacuc aaugacacca      300

acacaacacc accaaccaaa ccuaccacua ccagcacaac aaccuuucca accacaacca      360

guacaaccac aaccacacca accacuacaa ccacaaucac caaugcaccc aauacaacca      420

uuacuaccac aaccaccacu accaccaaug uucucaaugc aaucacuacu accagaccua      480

ccacuagaag cauggccagc aacagacaaa accaaaagag aagaaguaga cuaa            534


<210>  727
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  727
augggaacau ggauauucuu cgccugccua cuaggcgcau cacuagcaau gccacuacca       60

ccacacccag gacacccagg auauauaaac uucucauacg aaguacuaac accucuaaaa      120

ugguaccaaa acaugauaag acauccauac acaucauacg gauacgaacc aaugggcgga      180

ugguuacacc accaaauaau accaguaguc ucccaacaaa caccacaauc acacgcauua      240

caaccccacc accacauacc caugguacca gcccaacaac caggaauacc acaacaacca      300

augaugccac uaccaggaca acacucaaug acaccaacac aacaccacca accaaaccuc      360

ccauuaccag cacaacaacc cuuccaacca caacccguac aaccacaacc acaccaacca      420

cuacaaccac aaucaccaau gcacccaaua caaccacuac uaccccaacc accacuacca      480

ccaauguucu caaugcaauc acuacuaccc gaccuaccau uagaagcaug gccagcaaca      540

gacaaaacaa aaagagaaga aguagacuaa                                       570


<210>  728
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  728
augggaacau ggauacuauu cgcaugccua cuaggagcag cauucucaau gccacuacca       60

ccacacccag gacacccagg auacauaaac uucucauacg aaguacuaac accacuaaaa      120

ugguaucaaa acaugauaag acacccauca cuauuaccag accuaccacu agaagcaugg      180

ccagcaacag acaaaacaaa aagagaagaa guagauuaa                             219


<210>  729
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  729
augggaacau ggauacuauu cgcaugccua cuaggagccg cauucucaau gccccuacca       60

ccacacccag gacacccagg cuacauaaac uucucauacg aagaccuaua ccuagaagca      120

auaagaauag acagaacagc auucguccua acaccauuaa aaugguacca aaacaugaua      180

agacacccau acacaucaua cggauacgaa ccaaugggag gcuggcuaca ccaccaaaua      240

auacccguag uaucccaaca aacaccacaa ucacacgcac uccaaccaca ccaucacaua      300

ccuaugguac cagcacaaca acccggaaua ccacaacaac caaugaugcc acuaccagga      360

caacacucaa ugacaccuac acaacaccac caaccaaacc uaccauuacc agcacaacaa      420

ccauuccaac cacaaccagu acaaccacaa ccacaccaac cccuacaacc acaaucacca      480

augcacccaa uacaaccacu acucccacaa ccaccccuac cacccauguu cucaaugcaa      540

ucuuuacuac cagauuuacc auuagaagca uggccagcaa cagacaaaac aaaaagagaa      600

gaaguagauu aa                                                          612


<210>  730
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  730
augggcacau ggauacuauu cgcaugccua cuaggagcag cauucuccau gccacuacca       60

ccacacccag gacacccagg auacauaaac uucucauacg aaguacucac cccacuaaaa      120

ugguaccaaa acaugauaag acacccaaca ccacaauccc acgcacucca accacaccac      180

cacauaccaa ugguaccagc acaacaacca ggaauaccac aacaaccaau gaugccacua      240

ccaggacaac acucaaugac accaacacaa caccaccaac ccaaccuacc acuaccagca      300

caacaaccau uucaaccaca accaguacaa ccacaaccac accaaccacu acaaccacaa      360

ucaccaaugc acccaauaca accacuacuc ccacaaccac cacuaccccc aauguucuca      420

augcaaucac uauuaccaga ccuaccacua gaagcauggc cagcaacaga caaaacaaaa      480

cgagaagaag uagacuaa                                                    498


<210>  731
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  731
augccacuac caccacaccc aggacaccca ggauacauaa acuuuucaua cgaaguacua       60

accccacuaa aaugguacca aaacaugaua agacaccccu acacaucaua cggcuacgaa      120

ccaaugggag gauggcuaca ccaccaaaua auaccaguag uaucacaaca aacaccacaa      180

ucacacgcac uccaaccaca ccaccacaua ccaaugguac cagcacaaca acccggaaua      240

ccacaacaac caaugaugcc acucccagga caacacucaa ugacaccaac acaacaccac      300

caaccaaacc uaccacuacc agcccaacaa ccauuccaac cacaaccagu acaaccacaa      360

ccacaccaac cacuacaacc acaaucacca augcacccaa uacaaccacu acuaccacaa      420

cccccacuac ccccaauguu cucaaugcaa ucacuacuac cagaccuacc acuagaagca      480

uggccagcaa ccgacaaaac aaaaagagaa gaagucgacu aa                         522


<210>  732
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  732
augccagggg uagcuagacu accucuacuc uuaggacucc uauuguuacc acggccagga       60

agaccguuag aucuagcgga cuacacauau gaucucgcag aagaagacga cagugaaccg      120

cuaaauuaca aagauccaug uaaagcggcc gcauuuuugg gagauauagc auuagaugaa      180

gaagacuuaa gagcauuuca aguacaacaa gcuguugauc uaagaagaca cacggcccga      240

aaaagcagua uaaaagcagc gguaccaggc aacacaagca cgccaucaug ccaaaguaca      300

aacggacaac cacaaagagg ggcuugcggg agauggagag gaagaagcag aagcagacgc      360

gcagcuacuu caagaccuga aagaguuugg ccugacggcg uaauaccauu cguaauagga      420

ggcaauuuua caggaaguca gcgcgcaguu uuucggcaag caaugcgcca cugggaaaaa      480

cauacuugug uaacauucuu agagcgaaca gaugaagauu ccuauauagu uuucacauac      540

aggcccugcg gauguuguuc auauguagga agacgcgggg gaggaccaca agcgauaagu      600

auaggaaaaa auugugacaa auucggaaua guuguccaug aauuagguca cguuguggga      660

uucuggcacg aacacacacg accagauaga gacagacaug uaaguauagu aagggaaaau      720

auacaaccag ggcaggaaua caacuuuuua aaaauggaac cccaagaggu agaaucacuu      780

ggcgaaacuu acgauuucga uaguauaaug cauuaugcua gaaauacauu uucgagagga      840

auauuccuag acacuauagu accgaaauac gaaguaaaug gagugaaacc cccaauaggc      900

caaagaacua gacuaucaaa aggagacaua gcacaggcaa gaaaauuaua uaaauguccc      960

gcguguggug aaacauuaca agauucuaca ggaaauuuuu caucuccuga auauccuaau     1020

ggcuauagug cacacaugca uuguguaugg cgcauuucag uaacaccagg agaaaaaauu     1080

auuuugaauu ucacaagucu agacuuauac agaaguagau uauguuggua ugacuaugua     1140

gaagucaggg auggauucug gagaaaagcu ccucuaaggg gaagauuuug uggaagcaaa     1200

uuaccugaac caauaguuag cacagauuca agacuuuggg uagaauuuag aaguaguuca     1260

aauuggguag gaaaaggauu uuucgcagug uaugaagcaa uuugcggugg agauguaaaa     1320

aaagacuaug ggcacauaca aagcccaaac uauccugaug auuauagacc aucaaaagua     1380

uguauauggc gaauacaagu uagugaaggg uuucacguag gauuaacuuu ucaauccuuc     1440

gaaauagaaa gacaugacuc uugcgcauau gauuauuuag aaguuagaga cggacauagu     1500

gagaguagua cucuaaucgg aagauacugc ggcuaugaaa aaccugauga cauuaaaagc     1560

acuagcucua gauuauggcu aaaauuugua agugauggua gcauaaauaa ggcagguuuu     1620

gcaguaaacu uuuuuaaaga gguugaugaa uguucgaggc cuaauagagg ugguugugaa     1680

caacggugcu ugaauacacu aggaagcuac aaaugcucau gcgauccagg cuacgaauua     1740

gcgccagaua aaagaagaug ugaagcagca uguggaggau uuuugacuaa acuaaaugga     1800

ucaauaacaa guccagguug gccgaaagaa uacccuccua auaaaaacug uauuuggcaa     1860

cuuguagcac cuacucaaua uagaauauca uugcaauucg auuuuuucga gacagaagga     1920

aacgacguau guaaauauga cuuuguggaa guaagaagug gucuaaccgc ugauaguaag     1980

cuacacggaa aauucugcgg uagugagaaa ccagaaguaa uaacgucaca auacaauaau     2040

augagaguug aauuuaagag ugacaauaca guuucaaaaa aaggauuuaa agcacauuuu     2100

uucucagaca aagaugagug uaguaaagau aauggaggau gccagcaaga cugcguaaau     2160

acauucggaa gcuaugaaug ucaaugucga uccggcuuug uauuacacga uaauaaacac     2220

gauuguaaag aagcuggaug cgaucacaaa guaacgagua cuagcggaac aauuacaagc     2280

ccaaauuggc cggacaaaua ucccucaaaa aaagaaugua cuugggcaau aucuucuaca     2340

ccgggucaua gagugaaauu aacauucaug gaaauggaca uagaaucaca accagaaugu     2400

gcauaugauc accuugaagu auucgauggu agagaugcua aagcuccagu acugggucgc     2460

uuuuguggaa guaaaaaacc cgagccugua uuagcaacag gaucaagaau guuccuuaga     2520

uucuacuccg acaauucagu acagagaaaa gguuuccaag cuucucacgc aacagaaugu     2580

ggaggccaag ugcgagcgga uguaaaaaca aaagacuuau auucucacgc acaguuugga     2640

gacaauaauu auccaggagg uguggauugu gaauggguua uagucgcaga agaaggauac     2700

ggaguagagc uagucuuuca aacauuugag guagaagaag aaacugauug uggauacgac     2760

uauauggaac ucuuugaugg auacgacuca acagcacccc gauuagguag auauugugga     2820

ucuggaccac ccgaagaagu auauuccgca ggagacagcg uauuagucaa guuccacucc     2880

gaugauacca ucacuaaaaa aggauuucau cuuagauaua caagcacaaa auuucaagac     2940

acucuucaca gccgaaaaua g                                               2961


<210>  733
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  733
augguagcug guacuagaug ccuacuagca uuacucuuac cacaaguauu acuaggagga       60

gcagcaggau uagucccaga acuagguaga agaaaauucg cagcugccuc aucaggaaga      120

cccagcucac aaccuucaga cgaaguccua ucagaauuug aauugagauu acuaucaaug      180

uucggacuua aacaaagacc aacaccauca agagaugcag uaguaccacc auauaugcua      240

gauuuauaua gaagacacuc aggacaacca ggaaguccag cuccagacca uagauuagaa      300

agagcagcaa guagagcaaa cacagucagg agcuuucauc acgaagaauc acuagaagaa      360

uuaccagaaa caucaggaaa aaccacaaga agauuuuucu uuaaccuuag uucaauacca      420

acagaagaau ucaucacaag ugcagaacua caagucuuca gggaacaaau gcaggacgca      480

cuaggaaaua auucaucauu ccaucauaga auaaauaucu augaaauaau aaaaccagca      540

acagccaacu caaaauuccc aguaacaaga cuacuagaca caagacuagu aaaccaaaac      600

gcaagcagau gggaaagcuu ugauguaaca ccagcaguaa ugcgauggac agcacaaggu      660

cacgcaaauc acggauucgu agucgaaguc gcgcaucuag aagaaaaaca agguguaagc      720

aaacgacaug uaagaauaag uagaaguuua caccaagaug aacauucaug gucacaaaua      780

agaccacucc uaguaacauu cggacaugac gguaaaggac acccacuaca caaacgagaa      840

aaaagacaag caaaacauaa acaaagaaaa agacuaaaau caucaugcaa aagacauccg      900

uuauauguug acuuuucaga uguaggaugg aacgacugga ucguagcacc cccaggauau      960

cacgcauucu auugucaugg agaaugucca uuuccauuag cagaucacuu aaauagcaca     1020

aaccacgcca uuguacaaac ucuagucaau ucagucaauu caaaaauccc aaaagcaugc     1080

ugcguaccua cagaacuauc agcaauuuca augcuauacc uagacgaaaa ugaaaaagua     1140

guacuuaaaa acuaucaaga caugguugua gaaggaugug gaugcagaua a              1191


<210>  734
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  734
augauacccg gaaacagaau gcuaauggua guauuacuau gccaaguauu acuaggagga       60

gcuagccaug ccagcuuaau uccugaaaca ggcaaaaaga aaguagcaga aauacaagga      120

cacgcaggag gaagaagauc aggacaaagc caugaacuac uaagagacuu cgaagcaaca      180

uuacuacaaa uguuuggacu acgacgaaga ccacaaccua guaaaagcgc agucauacca      240

gacuauauga gagaucuaua ucgcuuacaa agcggagaag aagaagaaga acaaauacau      300

ucaacaggau uagaauaccc agaaagaccc gcaucaagag caaauacagu gaggucauuc      360

caucaugaag aacaucuaga aaauauacca ggaacaucag aaaauucagc auucagauuu      420

uuauucaauu uaaguucuau accagaaaac gaaguaauau caucugcaga acuaagauua      480

uucagagaac aaguugauca aggaccagac ugggaaagag guuuucacag aauaaauauc      540

uaugaaguaa ugaaaccucc agcagaagua guuccagggc aucuaaucac aagauuacuc      600

gauacaagau uaguacacca uaacguaaca cgaugggaaa cauuugaugu aucaccagca      660

guucuaagau ggacaagaga aaaacaaccg aauuacggau uagcaauaga aguuacucac      720

uuacaucaaa caagaaccca ccaaggacaa cauguaagaa uaucccgauc auuaccacaa      780

ggcucaggaa auugggcaca acuaagacca cuccucguaa cauuuggaca ugacggaaga      840

ggacaugcuc ucaccagaag aagacgagca aaaagaucac caaaacacca uagccaaaga      900

gcuagaaaga aaaauaaaaa uugcagaaga cauaguuuau acguugacuu cucagaugua      960

ggauggaaug auuggauagu agcaccaccu gguuaccaag cauuuuauug ucacggagac     1020

uguccauuuc cuuuagcaga ucacuuaaac aguacaaauc acgcaauagu acaaacucua     1080

guuaacucag uaaacagcuc uauaccaaaa gcaugcugug ucccaacaga acuaucggca     1140

auuucaaugu uauauuuaga ugaauaugau aaaguaguac uuaaaaauua ucaagaaaug     1200

guaguagaag gaugcggaug uagauaa                                         1227


<210>  735
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  735
augccaggau uaggucguag agcacaaugg uuaugcuggu ggugggguuu acuauguuca       60

uguuguggcc caccaccccu aagaccacca uuacccgcag cagcggcugc agccgcagga      120

ggacaacuau uaggagaugg aggaagucca ggcagaacag aacaaccacc gccaagcccc      180

caaagcucau cuggauuucu auacagaaga uuaaaaacac aagaaaagag agaaaugcaa      240

aaagaaauac uaucgguauu aggacugcca caucgaccca gaccacuaca cggauuacaa      300

caaccccaac cacccgcacu ucgacaacaa gaagaacaac aacaacaaca acaacuacca      360

agaggcgaac cuccaccagg aagauuaaaa ucagcaccac uauuuauguu agauuuauau      420

aacgcauuau cagcagacaa ugacgaagac ggagcaucag aaggagaaag acaacaauca      480

uggccccaug aagcagcauc aaguucacaa cgaagacaac caccuccagg agcugcucau      540

ccauuaaaca gaaaaucacu ucucgcccca ggaaguggcu cuggaggugc aaguccauua      600

acaucagcac aagauagcgc uuucuuaaau gaugcagaua ugguaauguc auuuguaaau      660

cuagucgaau acgauaaaga auuuucacca agacaacgac aucauaaaga auuuaaauuc      720

aauuuaaguc aaauaccuga aggugaagua guuacagcug cugaauuucg aauauauaaa      780

gacuguguaa ugggaucauu uaaaaaccaa acauucuuaa uaucaauaua ucaaguuuua      840

caagaacauc aacauagaga uagugaucuc uuuuuacuag auacaagagu aguaugggcu      900

agugaagaag guugguuaga auuugacaua acagcuacga guaauuuaug gguuguaaca      960

ccacaacaua auaugggucu acaacuuagc guaguuacac gagauggugu acauguacac     1020

ccaagagcag caggucuagu aggaagggau ggaccuuaug acaagcaacc auucauggua     1080

gcauucuuua aaguaagcga aguucaugua agaacuacaa gaucagcuuc aucaagaaga     1140

agacaacaaa gucgaaacag aaguacacaa agucaagaug uugcaagagu auccagugca     1200

ucugauuaua acaguagcga acuaaaaacc gcauguagaa aacacgaauu auacgucagc     1260

uuucaagauc uaggauggca agauuggaua aucgcaccaa aaggauaugc agccaauuau     1320

ugugauggag aaugcaguuu uccuuuaaau gcacacauga augcaacaaa ucacgcuaua     1380

guucaaacac uuguucacuu aaugaauccu gaauacguac caaaaccaug uugcgcaccu     1440

acaaaauuaa acgcaauauc aguacuauac uuugaugaua auucaaacgu aauacuuaaa     1500

aaguauagaa auaugguagu aagagcaugu gguugucacu aa                        1542


<210>  736
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  736
augcauguaa gaucacuccg agcagcagca ccacacucau uuguagcauu augggcacca       60

cuauucuuau uaagauccgc acucgcagac uucaguuuag acaaugaagu acacucauca      120

uuuauacauc gaagauuacg aucccaagaa aggagagaaa ugcaaagaga aauacucuca      180

auacuagguu uaccccacag accaagacca caccuacaag gaaaacauaa uuccgcacca      240

auguucaugc uagaucuaua caacgcaaug gcaguagaag aaggaggagg accaggaggc      300

caagguuucu cauacccaua uaaagcagua uucaguacac aaggaccucc acuagcaucc      360

cuacaagauu cucacuucuu aacugaugca gauaugguca ugucauucgu uaacuuagua      420

gaacaugaua aagaauuuuu ucacccaaga uaucaccauc gugaauuuag auucgaccua      480

ucaaaaauuc cagaaggaga agccguaaca gcagcagaau ucaggauuua uaaagacuau      540

auccgagaac gauucgacaa cgaaacauuc agaauaucag uauaucaagu cuuacaagaa      600

caucucggcc gagaaucaga cuuauucuua uuagauucga gaacucuaug ggcaucugaa      660

gaaggauggu uaguauuuga uauaacagca acaagcaauc auuggguagu aaacccccga      720

cauaaucuag gauuacaauu aucaguagaa acacuugaug gccaaagcau uaacccaaaa      780

uuagcaggac uaauaggcag acauggucca caaaacaaac aaccauucau gguagcauuu      840

uucaaagcaa cagaagucca uuucagaagu auaagaucaa caggaaguaa acaaagauca      900

caaaacagau caaaaacacc aaaaaaucaa gaagcacuaa gaauggcuaa cguagcagaa      960

aauagcucua gugaccaaag gcaagccugu aaaaaacacg aauuauaugu aucauucaga     1020

gauuuaggau ggcaagauug gaucauagca ccagaaggau augcagcaua uuacugugaa     1080

ggagaaugug cuuucccauu aaacucauac augaacgcaa caaaucacgc aaucguacaa     1140

acacucguac acuuuauuaa uccagaaaca guaccaaaac ccugcugcgc acccacacaa     1200

uuaaacgcaa uaucaguacu auacuuugac gauucaucaa acguaauauu aaaaaaauac     1260

agaaacaugg ucguaagagc augugguugc cauuaa                               1296


<210>  737
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  737
augaaagcau cagcagcacu acuaugccua cuacuaacag cagcagcauu cucaccacaa       60

ggacuagcac aaccaguagg aauaaacaca ucaacaacau gcugcuacag auucauaaac      120

aaaaaaauac caaaacaaag acuagaauca uacagaagaa caacaucauc acacugccca      180

agagaagcag uaauauucaa aacaaaacua gacaaagaaa uaugcgcaga cccaacacaa      240

aaauggguac aagacuucau gaaacaccua gacaaaaaaa cacaaacacc aaaacuauaa      300


<210>  738
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  738
auguuacuaa cuuugauaau auuauuacca guuguuucaa aauuuucuuu ugugucauua       60

ucugcaccgc aacacuggag uuguccagaa ggaacucuag cuggaaaugg aaauucuaca      120

uguguugggc cugcaccauu ucuaauauuc agccauggaa acucaauuuu cagaauagau      180

acugagggaa ccaacuauga gcaacucguu gucgacgcug gaguaucugu aauaauggau      240

uuucauuaca augagaaacg cauauacugg guugacuuag aacgacaauu auuacaaaga      300

guauuucuaa auggaagcag acaagaaagg guaugcaaua uagagaaaaa ugugagugga      360

auggcaauca auuggauaaa ugaagaagug auauggucaa accaacaaga aggaauuaua      420

acaguaacag auaugaaagg caauaauagc cauauacugu ugagcgcccu uaaauaucca      480

gcuaacguag caguagaucc aguagaaaga uuuauauuuu ggaguucuga agucgcagga      540

ucacuauacc gagcugaccu ugauggagua gguguaaagg cuuuacuaga aacaucagag      600

aaaaucacag caguaagucu ugacguacua gauaaaagau uauucuggau ccaauauaac      660

cgcgaagggu cuaauucccu uauauguuca ugugacuacg acggaggcuc aguacauaua      720

ucaaaacauc cgacccaaca uaaucuauuu gcuaugagcc uuuucgggga cagaaucuuu      780

uauucgacau ggaaaaugaa aacaauuugg auagcaaaua aacacacagg aaaagacaug      840

guaagaauua auuuacauag cucuuucgua ccuuugggag aauuaaaagu aguacauccg      900

uuggcacagc cuaaagcaga agacgauaca ugggaaccug aacaaaaauu gugcaaauug      960

cgaaaaggaa acuguucauc gaccguuugu ggacaagacu uacaaaguca cuugugcaug     1020

ugugcggaag gauaugcucu auccagagau agaaaauauu gugaagaugu caacgaaugu     1080

gcuuuuugga aucauggaug cacacuagga ugcaaaaaca caccagguuc uuauuacugu     1140

accuguccag uagguuuugu uuuacuacca gacgguaaaa gaugucacca gcuaguaucg     1200

uguccacgca acguaucuga auguucucac gauuguguac uuaccagcga aggaccauua     1260

uguuuuuguc cggagggaag uguacuagaa cgugacggua aaacauguuc aggaugcuca     1320

ucaccugaua acggugguug uagucaauua ugcgucccac uuaguccugu aaguugggaa     1380

ugugacugcu ucccaggaua ugauuugcaa uuagaugaga aaagcugugc agccagcgga     1440

ccucaacccu uucuccuuuu cgcaaacagc caagauauaa gacauaugca uuuugaugga     1500

acugauuaug gaacgcuauu aagucaacaa augggaaugg uuuacgcacu agaucaugau     1560

ccuguagaaa auaaaauaua uuuugcucac acagccuuaa aauggauaga acgggcaaau     1620

auggacggua gccaaagaga acgacuaauc gaagaaggag uagauguucc ugaaggauua     1680

gcaguagauu ggaucggaag acgauuuuau uggacggaua ggggaaaaag ccuaauuggu     1740

agauccgacc uuaauggaaa aagaucaaaa auaauaacaa aagaaaacau aagccaacca     1800

cgcggaauug cgguacaucc aauggcaaaa cggcuauuuu ggacagauac aggaauaaac     1860

ccaagaauag aaaguucuuc uuuacaggga cuaggacguc uaguaauagc aagcuccgau     1920

uuaauuuggc ccagugguau aacgauagac uuuuuaacug auaaacuaua cuggugugau     1980

gcaaagcaau cagucauuga aauggcaaau cuagauggau cuaaaagaag aagacuaacu     2040

caaaacgaug uaggacaccc auuugccgua gcaguauuug aagauuaugu uugguucuca     2100

gauugggcaa ugccaagcgu aaugagagua aauaaaagaa caggaaaaga uagagucaga     2160

uugcaaggaa gcauguuaaa accguccagu cuugucgucg uucauccccu ugcaaaacca     2220

ggugcggauc caugucuaua ucaaaacgga ggaugugaac auauuugcaa gaaacgguua     2280

gguacugcau ggugcagcug ucgagaagga uucaugaaag cgagcgaugg uaaaacaugu     2340

uuagcacucg auggacauca acuacuagcu ggcggagaag uagaccugaa aaaccaagug     2400

acaccccuug auauacuuag uaaaaccaga guaagugaag auaauauaac ggaaucacaa     2460

cauauguuag uagcagaaau cauggugagc gaucaagaug auugugcacc cguaggaugu     2520

aguauguaug caagaugcau cucagaagga gaagacgcaa ccugccagug cuuaaaaggc     2580

uuugccggcg acggcaaacu gugcucagau auugaugagu gcgaaauggg ugugcccguu     2640

uguccuccag cgucauccaa auguauaaau acagaaggag guuauguaug uagaugcagc     2700

gaggguuauc aaggugaugg cauacacugu uuggauaucg augaauguca auuaggagaa     2760

cauucuugug gggaaaaugc aaguuguaca aauacagaag gagguuauac uuguaugugu     2820

gcuggccguu uaagugaacc uggcuuaaua uguccagaca gcacuccgcc uccucaccua     2880

agagaggaug aucaccauua cagcguacgc aauagcgauu cagaaugccc ucuaagucac     2940

gacggguacu gucuacauga cggaguaugu auguacauag aggcuuuaga uaaguaugca     3000

uguaacugug ucguugguua cauaggagaa agaugucaau aucgagauuu aaaauggugg     3060

gaauuaagac acgcgggaca uggccaacaa caaaaaguaa uagucguagc cgucugcgua     3120

guuguucuag uaauguuacu acuacugagu cuuuggggug cacacuauua uagaacacaa     3180

aaacuacuau cgaaaaaucc caaaaaucca uaugaagaaa gcaguagaga uguaagguca     3240

agacgaccgg cugacacaga agaugggaug ucaaguugcc cacaaccaug guuuguagua     3300

auaaaagagc aucaagaccu uaaaaacgga ggucagccag uagcuggaga agacggucag     3360

gcugcggaug ggaguaugca accaacaucu uggagacaag aaccucaacu gugcggaaug     3420

gguacggagc aaggcugcug gaucccuguc agcucagaca aaggcagcug uccucaagug     3480

auggaacgau cauuccauau gccgucauac gggacacaaa cguuggaagg aggaguggaa     3540

aaaccacaua gucuauuauc cgcaaaccca uuauggcaac aacgagcauu agauccaccu     3600

caucaaaugg aauuaacuca auaa                                            3624


<210>  739
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  739
augacagcag guagaagaau ggaaauguua ugcgcaggaa gaguacccgc acuacuacua       60

ugccuaggau uccaccuauu acaagcagua cuaucaacaa caguaauacc aagcugcaua      120

ccaggagaau caucagacaa cugcacagca cuaguacaaa cagaagacaa uccaagagua      180

gcacaaguau caauaaccaa augcucauca gacaugaacg gauacugcuu acacggacaa      240

ugcauauacc uaguagacau gucacaaaac uacugcagau gcgaagucgg auacacagga      300

guaagaugug aacacuuuuu ucuaacagua caucaaccac uaucaaaaga auacguagca      360

cuaacaguaa uauuaauaau acuauuucua auaacaguag ucggaucaac auacuacuuc      420

ugcagauggu acagaaacag aaaaucaaaa gaaccaaaaa aagaauacga aagaguaaca      480

ucaggagacc cagaacuacc acaaguauaa                                       510


<210>  740
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  740
auggcagaag gagaaauaac aacauucaca gcacuaacag aaaaauucaa ccuaccacca       60

ggaaacuaca aaaaaccaaa acuacuauac ugcucaaacg gaggacacuu ccuaagaaua      120

cuaccagacg gaacaguaga cggaacaaga gacagaagcg accaacacau acaacuacaa      180

cuaucagcag aaucaguagg agaaguauac auaaaaucaa cagaaacagg acaauaccua      240

gcaauggaca cagacggacu acuauacgga ucacaaacac caaacgaaga augccuauuc      300

uuagaaagac uagaagaaaa ccacuacaac acauacauau caaaaaaaca ugcagaaaaa      360

aacugguucg uaggacuaaa aaaaaacgga ucauguaaaa gaggaccaag aacacacuac      420

ggacaaaaag caauacuauu ccuaccauua ccagucucaa gcgacuaa                   468


<210>  741
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  741
augguugggg uaggaggagg agacguagaa gauguaacac caaggccagg aggaugucaa       60

auaagcggaa gaggagcaag aggauguaau gggauaccag gagcggcagc augggaagcu      120

gcauuaccaa gaagaagacc uaggagacau ccaaguguua auccaagauc uagagcagcg      180

gggaguccaa gaacaagagg aagaagaaca gaagaaagac caaguggguc aagauuagga      240

gauagaggua gggggagagc auuaccaggu ggaagauuag gagguagagg aagaggaaga      300

gcaccagaaa gagugggagg aagaggaagg ggaagaggaa cagcagcacc aagagcagca      360

ccagcugcaa gaggaaguag accagggccg gcaggaacaa uggcagcagg aaguauaaca      420

acauuaccag cauuaccaga agacggagga ucaggagcau uuccaccagg acauuuuaaa      480

gacccaaaaa gauuauauug uaaaaacgga ggauuuuuuc uaagaauaca uccagaugga      540

agagucgaug gugugaggga aaaaagugau ccgcauauaa aauuacaauu acaagcagaa      600

gaacgaggag uuguaaguau aaaaggagua ugugcaaaua gauaucuagc aaugaaagaa      660

gauggaagau uauuagcaag uaaaugugua acagacgaau guuuuuuuuu ugaaagauua      720

gaaagcaaua auuauaauac uuauagaagu agaaaauaua caagcuggua uguagcuuua      780

aaaagaacag gacaauauaa acuaggaagu aaaacaggac caggacaaaa agcaauacua      840

uuucuaccaa ugagcgcaaa gucauaa                                          867


<210>  742
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  742
augcacaaau ggauacuaac auggauacua ccaacacuac uauacagaag cugcuuccac       60

auaauaugcc uaguaggaac aauaagccua gcaugcaacg acaugacacc agaacaaaug      120

gcaacaaacg uaaacugcuc aucaccagaa cgacacacaa gaucauacga cuacauggaa      180

ggaggagaca uacgaguaag aagacuauuc ugcagaacac aaugguaccu aagaauagac      240

aaaagaggaa aaguaaaagg cacucaagaa augaaaaaca acuacaacau aauggaaaua      300

agaacaguag cagucggaau cguagcaaua aaaggaguag aaucagaauu cuauuuagca      360

augaacaaag aaggaaaacu auacgcaaaa aaagaaugca acgaagacug caacuucaaa      420

gaauuaauac uagaaaacca cuacaacaca uacgcaucag ccaaauggac acacaacgga      480

ggagaaaugu ucguagcacu aaaccaaaaa ggaauaccag uaagaggaaa aaaaacaaaa      540

aaagaacaaa aaacagcaca cuuccuacca auggcaauaa cauaa                      585


<210>  743
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  743
augaaacuac uaccaucagu aguacuaaaa cuauuuuuag cagcaguacu aucagcacua       60

guaacuggag aaucacuaga aagauuaaga agaggacuag cagcaggaac cucaaaucca      120

gacccaccaa caguaagcac agaccaauua uuaccacuag gaggaggaag agacagaaaa      180

guaagagacc uacaagaagc agaccuagac cuauuaagag uaacacuauc aucaaaacca      240

caagcacuag caacaccaaa caaagaagaa cacggaaaaa gaaaaaaaaa aggaaaagga      300

cuaggaaaaa aaagagaccc augccuaaga aaauauaaag acuucugcau acacggagaa      360

ugcaaauacg ucaaagaacu aagagcacca agcugcauau gccaccccgg auaccaugga      420

gaaagaugcc acggacuauc acuaccagua gaaaaccgac uauacacaua cgaucacaca      480

acaauauuag caguaguagc aguaguauua ucaucaguau gcuuacuagu aauaguagga      540

cuauuaaugu ucagauacca cagacgagga ggauacgaug uagaaaauga agaaaaagua      600

aaacuaggaa ugacaaauuc acauuaa                                          627


<210>  744
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  744
auguggguaa cuaaacuuuu accagcguua uuacuccaac acguauuacu acaccuccua       60

uuauuaccaa uagcuauacc auaugcagaa ggacaaagaa aacgcagaaa caccauacau      120

gaauuuaaaa aaucggccaa aacaacucua aucaaaauag auccagcauu aaaaauaaaa      180

acaaaaaaag uuaacacagc cgaucaaugu gcaaaccgcu gcacacguaa uaaaggccua      240

ccauucacau gcaaagcauu uguauuugau aaagcacgua agcaaugucu augguuucca      300

uuuaauagca ugagcucugg cguaaaaaaa gaauuuggac augaauuuga ccuauacgaa      360

aauaaagacu auauuagaaa cuguauuaua ggaaaaggaa gaucauauaa gggcacagua      420

uccauaacaa aaucaggaau uaaaugucaa ccauggucau ccaugauacc ccacgaacau      480

ucauuuuuac caucaaguua uagaggaaaa gauuuacaag aaaacuauug ccgaaaccca      540

agaggagaag aaggcggacc uugguguuuu acaucaaacc cagaagucag auaugaaguu      600

ugugauauac cccaauguuc agaaguagaa uguaugacau guaauggaga aucauauaga      660

ggucuaaugg aucacacaga aagugguaag auaugccaaa gaugggauca ucagacacca      720

caccgacaua aauuuuuacc cgaaagauac ccugauaaag gauuugauga uaauuacugu      780

cgaaacccug augggcagcc aagaccaugg uguuauacuu uagaccccca cacaagaugg      840

gaauauugcg cuauaaaaac augcgcggau aauacaauga augauacaga uguacccuua      900

gaaacuacug aauguauaca aggacaaggu gaggguuauc gcggcacugu caauacuaua      960

uggaauggca uccccuguca aagaugggau ucacaauauc cccaugaaca ugauaugaca     1020

ccagaaaacu uuaaauguaa agauuuacga gaaaauuauu gccguaaucc agaugguuca     1080

gaaucucccu ggugcuuuac aaccgaucca aauaucagag ucggguacug uucacagaua     1140

ccaaauugcg acaugucuca uggucaagau uguuauaggg gaaacggaaa aaauuauaug     1200

ggaaacuuau cucaaacuag aucagguuua acuuguagua ugugggauaa aaauauggaa     1260

gauuuacaca gacauauauu cugggaaccu gaugcaagca aacuaaacga aaacuacugu     1320

aggaauccag acgaugaugc acauggcccu uggugcuaua caggaaaucc auuaaucccg     1380

ugggauuauu gucccauauc gcgaugugaa ggcgacacaa cgccaacuau aguaaaccua     1440

gaucauccag ugauaucaug ugcaaaaacu aaacaauuaa gagucguaaa uggaauacca     1500

acaagaacaa acauuggaug gaugguauca cuccgauaca gaaauaaaca uauaugugga     1560

ggaucauuaa uaaaagaaag cuggguuuua accgcaagac aauguuuucc aucucgagac     1620

cuuaaagacu augaagcaug guuaggaaua cacgacguac augguagagg agacgaaaaa     1680

uguaaacaag uacuaaaugu uucccaacuu guauaugguc cagaagguuc agauuuagua     1740

uuaaugaaau uagcgagacc cgcaguuuua gaugauuucg uaagcaccau agaccuaccg     1800

aauuauggau guacuauacc agaaaaaaca aguuguagug uauacggaug gggauauaca     1860

ggccuaauaa auuaugacgg auuacuaaga gucgcacacu uauauauaau gggaaacgaa     1920

aaauguucac aacaucacag agguaaagua acauuaaaug aaagugaaau augugcagga     1980

gcugaaaaaa uaggcucagg accgugugaa ggagauuaug gaggcccacu aguaugugaa     2040

cagcacaaaa ugagaauggu acuaggagua auaguaccag gccgaggaug ugcaauccca     2100

aacagaccag gaaucuuugu uagagucgcu uacuaugcua aauggauaca uaaaauaaua     2160

cuaacauaua aaguaccaca aucauaa                                         2187


<210>  745
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  745
auggcaaaag cagcagcaau uggaauagau uuggguacaa cauacaguug cgugggcgug       60

uuucaacacg gaaaaguaga aauaauagca aacgaucaag gaaacaggac aacaccauca      120

uacguggcau uuacagacac agaacgauua auaggggacg cugcuaaaaa ccaaguagca      180

uuaaaccccc aaaacacagu guucgaugcg aaaaggcuua uaggucggaa auuuggggau      240

cccguagucc aaagcgauau gaaacauugg ccauuccaag ucauuaauga uggagauaaa      300

ccaaaagugc aaguaaguua caagggugaa acaaaagcau uuuacccgga agaaauauca      360

aguaugguac uaacuaaaau gaaggaaaua gcugaagcau accuaggaua cccaguaaca      420

aaugcgguaa uaacagugcc agccuacuuu aacgauucgc aacgacaagc aacgaaagac      480

gcagggguca uagccggucu aaaugucuua agaauaauaa augaaccaac agcagcagcg      540

auagcuuacg gacuagauag aacaggaaaa ggugaaagaa acguacuaau auuugauuug      600

ggaggaggaa cauuugacgu aucgauauua accauagaug acggcauauu ugaaguaaag      660

gcaacggcag gagacacaca ucugggagga gaagacuuug auaaucggcu aguaaaucac      720

uuugucgaag aauuuaaaag aaaacacaag aaagauauaa gucaaaacaa aagagcagua      780

agaagacuua gaaccgccug cgaaagagca aaaagaacac uaagcucauc aacacaagca      840

aguuuggaaa uagauucauu auuugaaggu auagacuucu auacuucaau uacaagagcc      900

agauucgaag aacuauguag ugauuuauuu agaaguacgu uagaaccggu agaaaaagcg      960

uuaagagaug cuaaacuaga uaaagcucaa auccaugauc uaguauuagu aggaggaagu     1020

acaagaauac caaaagugca aaaauuacuu caagauuucu uuaacggaag agaucuaaau     1080

aaaucgauaa auccagauga agcgguagcg uacggagcag caguacaagc agcaauauug     1140

augggagaua aaagugaaaa cguucaagau uuauuauuac uagauguagc cccauuaagu     1200

uuaggacucg agacagcugg uggaguuaug acagcgcuaa uaaaaaggaa cucaacaaua     1260

ccaacaaaac aaacacaaau auuuacaaca uauagugaua aucaaccagg aguacuaaua     1320

caaguauaug aaggagaaag agcgaugaca aaagacaaua auuuacuugg aagauucgaa     1380

cuuaguggaa uaccaccagc accacgagga guaccacaaa uagaaguaac guuugauauu     1440

gacgcaaacg gaauacuaaa uguaaccgcu acagauaaaa gcacaggaaa agcaaacaaa     1500

auaacuauaa caaaugauaa agguagauua aguaaagaag aaauagaacg uaugguacaa     1560

gaagcagaaa aauacaaagc agaagacgaa guacaaagag aaagggucag cgcgaaaaau     1620

gcacuagaaa guuacgcauu caauaugaaa agugcaguag aagaugaagg acucaaagga     1680

aaaauaagug aagcagauaa aaagaaaguc uuagauaaau gucaagaagu gauaagcugg     1740

cuagaugcaa auacauuagc ugaaaaagac gaauuugaac auaaaagaaa agaacuagag     1800

caaguaugca acccaauaau aaguggcuug uaccaagggg caggaggacc ggggccagga     1860

ggcuuuggag cucaaggacc uaaaggagga agcgguagcg gaccaacaau agaagaagua     1920

gacuaa                                                                1926


<210>  746
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  746
auggcaaaag cagcagcgau aggaauagau uuagggacaa cuuauaguug uguaggagua       60

uuccaacaug gaaaaguaga aauaauagcu aaugaccaag gaaauagaac aacuccuagu      120

uauguagcau uuacagacac agaaagacua auaggagacg ccgcuaaaaa ucaaguagcc      180

cucaauccac agaauacagu auucgacgca aaaagacuua uagguaggaa auucggagau      240

ccagugguac aaagcgauau gaaacauugg ccauuucaag uaauaaauga cggagauaaa      300

ccaaaaguac aaguaucaua caaaggagaa acaaaagcau uuuauccuga agaaaucuca      360

aguaugguac uaacaaagau gaaggaaauu gcagaagcau aucuuggaua cccaguaacg      420

aacgcaguaa uaacaguacc ugccuacuuu aacgacagcc aacgucaagc aacuaaagac      480

gcaggaguaa uagcuggucu aaacguacuu agaauuauca augaaccaac ugcagccgca      540

aucgcauacg gacuagaccg aacgggaaaa ggagaaagga auguauuaau uuucgaccua      600

ggaggaggaa cauucgaugu cucuauauua acuauagacg auggaauuuu ugaaguaaaa      660

gcaacggcag gagacacgca uuuaggagga gaagauuucg auaaccgucu aguaaaucau      720

uucguugaag aauuuaaaag aaaacauaaa aaggacauuu cgcaaaauaa aagagcagug      780

agaagauuaa gaaccgccug ugaaagagca aaaagaacau uaagcagcag uacgcaagca      840

agccuugaaa uagauucacu auuugaagga auagauuucu acacaucaau aacaagagcu      900

cgauuugaag aauuauguag cgacuuguuc agaucaacau uagagccagu agaaaaagca      960

cuaagagacg caaaauuaga caaagcacaa auacaugacc uaguauuagu uggaggcagu     1020

acacgaauac caaaaguaca aaaacuucua caagacuucu uuaauggaag agaucuaaau     1080

aaaucaauaa auccagauga agcaguagcc uacggugcgg cgguucaagc agcaauacug     1140

augggggaca aaucagaaaa uguacaagau uuauuauuau uagauguggc accacuauca     1200

uuaggauuag aaacagcugg agguguaaug acagcacuaa uuaaacgaaa cagcaccaua     1260

ccaacgaaac aaacacaaau auuuaccacg uacucggaca aucaaccggg aguauugaua     1320

caaguauacg aaggagaaag agcaaugacu aaagacaaca aucuauuagg aagauucgaa     1380

uuaucaggaa uaccgccagc accaagagga guaccacaaa uagaaguaac auucgauaua     1440

gacgcaaaug gcauuuuaaa cguaacagca acagacaaau caacagguaa agcaaacaaa     1500

auaacaauaa caaaugauaa aggaagacua ucuaaagaag aaauagaaag aaugguacaa     1560

gaagccgaaa aauacaaagc agaagaugaa guucaaagag aacgugugag ugccaagaau     1620

gcacuugaau cguaugcguu caauaugaaa agcgcaguag aagaugaggg ccuaaaagga     1680

aaaauaucag aagcagacaa aaagaaaguc uuggauaagu gucaagaagu aauaaguugg     1740

uuagaugcaa acacacucgc agaaaaagau gaauuugaac auaaaagaaa agaacuagaa     1800

caaguaugca auccaauaau aucaggguua uaccaaggag caggcggacc aggacccggg     1860

ggauucggug cccagggacc aaaaggcggu aguggcagcg gaccaaccau ugaagaagua     1920

gauuaa                                                                1926


<210>  747
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  747
auggcuacag caaaaggaau agcaauagga auagauuuag gaacaacaua uucguguguu       60

ggaguauucc aacacggaaa aguagaaauc auagcaaaug accaaggaaa cagaacaaca      120

ccaagcuaug uagcauuuac ggauacagaa agauuaauag gagacgcagc caaaaaccaa      180

guagcuauga auccacaaaa uacaguauuc gaugcaaaaa gacuaauagg aagaaaauuu      240

aaugacccag uaguacaagc agauaugaag cuauggcccu uccaaguuau aaaugaagga      300

gggaaaccaa aaguucuagu aaguuauaaa ggugaaaaua aagccuucua uccagaagaa      360

auaucaagca ugguccuaac aaaacuaaaa gaaaccgcag aagcauucuu aggacauccu      420

gucacuaacg caguaauaac aguaccagca uacuucaacg auagucaacg ucaagcaaca      480

aaagaugcug gaguuauagc aggacuaaau guacuacgaa uaaucaacga accgacagca      540

gcagcuauag cauauggacu cgacaaaggc ggacaaggag aaagacacgu gcucaucuuc      600

gacuuaggcg guggcacauu ugauguaucc auacuaacca uugacgaugg aauuuucgaa      660

guaaaagcca cagccggaga cacccaucua gggggagaag auuucgauaa ccgguuagua      720

agucacuucg uagaagaauu uaaaagaaaa cacaagaaag auauaaguca aaauaaacga      780

gcaguaagaa gauuaagaac agcaugugaa agagccaaaa gaacacuuag uaguucaaca      840

caagcaaacu uagaaauaga uucauuauac gaaggaauag auuucuauac caguauaaca      900

agagcaagau uugaagaacu augcgcugau uuauuucgcg gaacauuaga acccgucgaa      960

aaagcauuaa gagaugcaaa aauggauaaa gcaaaaauac acgacauagu auuaguggga     1020

gguagcacgc gaauaccaaa gguucaacga uuauuacaag acuauuuuaa uggcagagac     1080

cucaauaaaa guauaaaccc ugaugaagca guugcauacg gagcugcagu acaagcagcu     1140

auacugaugg gagacaaauc agaaaaagua caagaucucc uacuacuaga cguagcucca     1200

cuaucacugg gucuugagac agcgggaggc guaaugacag cauuaauuaa aaggaacucg     1260

accauaccca caaaacaaac acaaauauuu accacauauu cagauaacca accuggagug     1320

cuuauucaag uauacgaagg agaaagagca augacgaaag auaauaacuu gcuaggaaga     1380

uuugaucuaa cagggauucc accagcacca agaggcgugc cacaaauaga agucaccuuc     1440

gacauagacg caaacggaau auuaaacguc acagcaaccg auaaaucaac agguaagguc     1500

aauaaaauua caauaacaaa cgauaaagga agacuaucaa aagaagaaau agaaagaaug     1560

guacuagaug cagaaaaaua caaagcagaa gacgaaguac aaagagagaa aauagcagcu     1620

aaaaacgcgc uagaaaguua cgcauuuaac augaaaagug uaguaucuga ugaaggauua     1680

aaaggcaaaa uuucagaaag cgauaaaaau aaaauacuag acaaaugcaa ugaacuacuu     1740

aguugguuag aaguaaauca acuagccgaa aaggaugaau uugaccauaa aagaaaagaa     1800

cuggaacaaa uguguaaucc caucauaaca aaacuauauc aaggaggcug cacaggacca     1860

gcauguggaa ccggauaugu accaggacgu ccagcaacag gaccaacaau agaagaagua     1920

gacuaa                                                                1926


<210>  748
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  748
augucagcaa gaggaccagc aauugggaua gaucuaggca caacuuacuc augcguaggu       60

guauuccaac acggaaaagu agaaauuaua gcaaacgauc aagggaacag aacaacacca      120

aguuauguag cauuuacaga cacugaaaga uuaauaggug acgcagcuaa aaaucaagua      180

gcaaugaacc cuacaaacac aauuuuugac gcaaaacgac uaaucggaag aaaauucgaa      240

gacgcaacag uacaaucaga uaugaaacau uggccguuca gaguaguaag cgaaggaggg      300

aaaccaaaag uacagguuga auacaaagga gaaacaaaaa cuuucuuccc agaagaaauu      360

aguaguaugg uccucacaaa aaugaaagaa auagcagaag cauaccuugg aggaaaaguu      420

cacucagcag uaauuacagu accagcauac uucaacgauu cccaaagaca agcaacgaaa      480

gacgccggua caauaacagg auuaaacgug uuaagaauua uaaacgaacc uaccgcagca      540

gccauagcgu auggauuaga uaagaaagga ugugcaggag gagagaaaaa uguauuaaua      600

uuugacuuag gcggugggac auuugaugua aguauacuga caauagaaga ugggauauuu      660

gaagucaaau cgacagcagg agacacacau uuagggggag aagacuuuga caacagaaug      720

guaagccauc uagcagaaga guucaaaaga aaacacaaga aagacauagg acccaauaaa      780

agagcuguca ggagacuuag aacagcaugc gaaagagcaa aaagaacauu aucaaguuca      840

acacaagcaa guauagaaau agauucgcua uaugaaggag uugauuucua uacaaguaua      900

acaagagcaa gauuugaaga acuaaacgcc gaucuauuua gaggaacauu agaaccgguu      960

gaaaaagcac uuagagacgc aaaauuggau aaaggccaaa uacaagaaau uguucuagua     1020

ggaggaagua cacgcauucc aaaaauacaa aaacuauuac aagacuuuuu caauggaaaa     1080

gaacucaaua aaucaauaaa cccugaugaa gcgguagcgu auggugcagc cguacaagcc     1140

gcaauauuaa ucggagacaa aagugaaaac guacaagacc uacuauuguu agauguaaca     1200

ccauuaucac ucggaauuga aacagcugga ggaguaauga caccacucau aaaaagaaau     1260

acaaccauuc ccacaaaaca aacacaaaca uucacaacgu acagcgauaa ccaaaguagc     1320

guccuaguac aaguauauga aggcgaaaga gcaaugacca aagacaacaa ucuauuagga     1380

aaauucgacu uaacaggaau accuccagca ccaaggggag uaccacaaau agaaguuaca     1440

uuugacauag augcuaacgg aauauuaaac guaacagcag cagauaaaag cacaggaaaa     1500

gagaauaaaa uaacaauuac aaacgauaaa ggaagacuaa gcaaagacga uauagauaga     1560

augguacaag aagcagaaag auauaaaagc gaagacgaag cuaacaggga ucgagucgca     1620

gccaaaaaug cauuggaaag cuauacauac aauauaaaac aaacuguaga agaugaaaaa     1680

uuaagaggaa agauaaguga acaagauaaa aauaaaauuu uagacaaaug ucaagaaguu     1740

auaaacuggu uagauagaaa ccaaauggcc gaaaaagacg aguacgaaca uaaacaaaaa     1800

gaacuagaaa gagucuguaa ucccauaauu agcaaauuau accaaggagg acccggaggu     1860

ggaaguggag gaggaggauc aggagcaagc ggaggcccaa caauagaaga gguugauuaa     1920


<210>  749
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  749
augagcgugg uagguauaga ucuuggauuc caaucauguu acguugccgu agcaagagca       60

ggaggaauag aaacaauagc caacgaauac agugacagau guacaccggc cugcauaucc      120

uuuggaccua aaaacagauc aaucggcgca gccgcaaaau cacaagugau uucaaaugcu      180

aaaaacacag ugcaagguuu caaaagauuc cacggacgag cauuuagcga cccauuuguu      240

gaagcagaaa aaucaaacuu agcuuaugau aucguacaau uacccacagg acuaacaggu      300

auaaaaguca cauauaugga agaggaaaga aacuucacaa ccgaacaagu aaccgcgaug      360

cuauuaucaa aacucaaaga aacagcagaa uccgucuuaa agaaaccugu cguugacugu      420

guaguaucag uacccugcuu cuacacagac gcagaaagaa gauccguaau ggaugccaca      480

caaauagcug gucugaauug cuuacgacua augaaugaaa cgacggcagu ugcauuagcu      540

uacggaauau auaaacaaga cuuacccgca cuagaagaaa aaccaagaaa cgucguauuu      600

guagauaugg gucacagugc auaucaagug uccguaugug cuuuuaacag agguaaacua      660

aaaguauuag caacagcuuu ugauacuacu uuaggcggac gaaaauuuga ugaaguucua      720

guaaaucauu uuugcgaaga auuugguaag aaauacaaac ucgauaucaa aucaaaaaua      780

cgugcauuau uacgacuuuc acaagaaugu gaaaaacuaa agaaauuaau gagugcaaac      840

gcaagcgacc ugccuuuauc uauagaaugu uucaugaacg auguagaugu aucgggcaca      900

augaacagag guaaauuccu cgaaaugugc aacgaucugu uagcaagagu agaaccacca      960

cuacgaagug uauuagaaca aacaaaacua aagaaagaag acauuuaugc aguagaaaua     1020

guuggagggg caacacgaau accagcggua aaagagaaaa uuucaaaauu cuuuggcaaa     1080

gaauuaucaa cuacacuuaa ugcagaugaa gccguaacua gaggaugugc acuccaaugu     1140

gcaauauuau caccagcuuu caaaguaaga gaauuuagca uaacagaugu aguaccauac     1200

ccaauuucac ugagauggaa cucaccagca gaagaagggu cauccgacug cgaaguauuc     1260

aguaaaaauc augcugcccc uuuuucaaaa guacuaacau ucuauagaaa agaaccuuuu     1320

acccuagaag cauacuauuc aucaccccaa gaucuuccau accccgaucc agcaauagcc     1380

caauuuagcg ugcaaaaagu uacaccucaa agugauggau caagcaguaa aguuaaagua     1440

aaaguccgug ugaacguuca ugguauauuu aguguaucuu cagccagccu aguagaagua     1500

cacaaaagcg aagaaaauga agaaccaaug gaaacggauc aaaaugcuaa agaagaagag     1560

aaaaugcaag uagaccaaga agaaccacau guagaggaac aacaacaaca aacacccgca     1620

gaaaacaaag ccgaaaguga agaaauggaa acaucucaag caggaucaaa ggauaagaaa     1680

auggaucaac cuccucaagc gaagaaagca aaaguaaaaa caucuacagu cgaucuucca     1740

auagaaaacc aacuuuuaug gcaaaucgau agagaaaugu uaaaccuaua uauagaaaac     1800

gaaggaaaaa ugauaaugca agacaaauua gaaaaagaaa gaaacgacgc uaaaaacgca     1860

guagaagaau auguuuauga aaugagagau aaacugagcg gagaauacga aaaauucgua     1920

agcgaagacg aucgaaauuc auucacccua aaacuugaag acacugaaaa cuggcucuac     1980

gaagauggag aagaccaacc aaaacaagua uacguagaua aacuagcaga acugaaaaac     2040

cuaggacaac caauaaaaau aagauuccaa gaaagugaag aacguccuaa auuauucgaa     2100

gaacuaggaa aacaaauaca acaauauaug aaaaucauau caaguuuuaa aaacaaagaa     2160

gaucaauacg accacuuaga ugccgcagac augacaaaag uagaaaaauc uacuaacgaa     2220

gccauggaau ggaugaauaa uaaauuaaac cuccagaaca aacaaucgcu aacaauggau     2280

ccagugguca aaucaaaaga aauagaagca aaaauuaaag aacuaacaag uacuugcuca     2340

ccaaucauaa gcaaaccaaa acccaaaguc gaaccaccaa aagaagaaca gaaaaacgca     2400

gaacaaaaug gaccaguaga cggccaaggu gacaacccag gaccacaagc agcggaacaa     2460

gguacugaca cagcaguacc cucagacagu gauaagaaac uaccagaaau ggauauagac     2520

uaa                                                                   2523


<210>  750
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  750
augucaguag ucggaauuga ccuuggauuu uuaaacugcu acauagcagu agcuagguca       60

ggaggaaucg aaacaauagc aaacgaauau agcgauagau gcaccccugc cugcauauca      120

uuaggaucac gcacuagagc aaucgggaac gcagccaaau cacaaauagu uacaaacgua      180

agaaauacaa uccacggauu caaaaaacua cacggcaggu ccuuugauga uccaauagua      240

caaacggaaa gaauaagacu acccuacgaa cugcaaaaaa ugcccaaugg aagugcaggc      300

gucaaaguca gauaucuaga agaagaaaga ccuuuugcaa uagaacaagu aaccggaaug      360

uuauuggcua agcuaaaaga aacuucagaa aacgcauuaa agaaaccugu agcagauugu      420

guuauaucaa uaccaucguu uuucacagau gcagaacgaa gaucaguaau ggcagcagca      480

caaguagccg gccuaaacug ucuucgacua augaaugaaa caacugcagu ugcccuagcu      540

uauggaauuu auaaacaaga uuuaccuccu cuagacgaaa aacccaggaa cguaguauuc      600

auagauaugg gucauagugc auaucaaguu cuagugugug cauuuaauaa aggaaaauua      660

aaaguccuag caacaacauu cgauccguau cuaggagggc gaaacuucga ugaggcacug      720

guagacuacu uuugugacga auucaaaacg aaauacaaga uuaacguaaa agaaaacagc      780

agagcucuuc uaaggcuaua ccaagaaugu gaaaaacuca aaaaauuaau guccgcuaau      840

gccucagacc uaccacuaaa uauagaaugu uucaugaaug auuuagaugu gucaaguaaa      900

augaacagag cacaauuuga acaauuaugc gcaucauuac uagcucgagu agaaccacca      960

uuaaaagccg uaauggaaca agcuaauuua caacgagaag auaucucauc aauagaaauc     1020

guuggaggag ccaccagaau uccagcggua aaagaacaaa uuacuaaauu uuuucuuaaa     1080

gacaucucaa caacacuaaa ugcugacgaa gcaguugccc ggggaugcgc ccuccaaugu     1140

gcaauacuua gcccugcauu uaaaguacga gaauuuucaa uaacagacuu aguuccauau     1200

ucgaucacau uaagauggaa aacaucauuc gaagacggca gcggcgaaug ugaaguauuc     1260

ugcaaaaacc acccagcccc uuuuagcaaa guaauaacau uucauaaaaa agaaccguuu     1320

gaauuagaag cauuuuacac aaacuuacac gaaguaccau acccugaugc acgaauaggu     1380

agcuuuacua uacaaaacgu auucccacaa uccgauggcg acagcucaaa aguuaaagua     1440

aaagucagag uaaacauaca uggaauuuuc ucugucgcau cagcaucugu uaucgaaaaa     1500

caaaaucuag aaggggacca uuccgacgcc ccaauggaaa ccgaaacaag cuuuaaaaau     1560

gaaaacaaag acaauaugga uaaaaugcaa guagaucaag aagaaggaca ucaaaaaugc     1620

caugcugagc auacaccaga agaagagaua gaccacacug gggcaaaaac aaaaucagcc     1680

guuucagaua aacaagauag auuaaaucaa acacuaaaaa aaggcaaggu aaaaucuauu     1740

gauuuaccaa uccaauccuc acucugcaga caauuaggac aagaucuauu aaauagcuau     1800

auagaaaaug aaggaaaaau gaucaugcaa gacaaacuag aaaaagaaag aaacgacgcc     1860

aaaaaugcag uugaagaaua cguauaugau uucagggacc gacuaggaac cguuuaugaa     1920

aaauuuauaa cgccagaaga ccuuucaaaa cuaagugcag uauuagaaga cacagagaac     1980

ugguuauaug aagauggaga agaccaacca aaacaaguau acguugacaa auuacaagaa     2040

cuaaagaaau acggacaacc aauacaaaug aaauacaugg agcacgaaga acguccaaaa     2100

gcacuaaacg accuaggcaa aaagauccaa cuuguaauga aaguaauaga agcuuauaga     2160

aauaaagaug aacgguauga ccaucuugac cccacagaaa uggaaaaagu ugaaaaaugc     2220

auaagcgacg caaugagcug gcucaacagc aaaaugaacg cacaaaacaa auuaucacua     2280

acacaagauc caguaguaaa agucagugaa auaguagcaa aaucaaaaga acuagacaau     2340

uucuguaauc caauaauaua caaacccaaa ccaaaagccg aaguccccga agacaaacca     2400

aaagcaaacu cagaacauaa ugguccaaug gauggacaau cuggaacaga gacaaaauca     2460

gacucaacua aagauucauc ccaacauacc aagaguagcg gggaaaugga agucgacuag     2520


<210>  751
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  751
augaaauuaa guuugguggc agcaaugcua uuauuauuaa gcgcugcaag agcagaagaa       60

gaggauaaaa aagaagaugu ugguacggug guuggaauug accuuggaac aacauacagc      120

ugugucggag uauuuaaaaa uggaagaguu gaaauuauag cuaacgauca ggggaauaga      180

auaacaccaa guuacguagc auucacacca gagggagaaa gauuaaucgg agacgcagca      240

aaaaaccaac uuacuaguaa uccagaaaau acaguauucg augcaaaaag auuaauagga      300

agaacaugga acgacccuuc cguacaacaa gauaucaaau uccuaccauu uaaaguugua      360

gaaaaaaaga caaaaccaua cauacaaguc gauauaggag gaggacaaac aaaaacauuu      420

gcgccagagg aaaucagugc aaugguauua acuaaaauga aagagacagc agaagcauac      480

uuagguaaaa aaguaacaca cgcaguaguc acaguaccag cauauuuuaa cgacgcacaa      540

agacaagcaa caaaggaugc aggaacaauc gcaggauuaa acguaaugag aauaauaaau      600

gagccaacag cagcagcaau ugcauaugga uuagacaaac gagaagguga gaaaaacauc      660

cugguauucg acuuaggagg gggcacauuu gacguaaguu uauuaacuau agauaaugga      720

guauuugaag uaguagcaac aaacggugac acacauuuag gaggagaaga uuucgaucag      780

agaguaaugg aacauuuuau aaaauuauac aaaaaaaaaa caggaaaaga uguaaggaaa      840

gacaauagag cagugcaaaa acuuaggaga gaagucgaaa aagcaaaacg agcccuaagu      900

agccaacauc aagcaagaau agaaauagaa agcuuuuaug aaggggaaga cuucagugaa      960

acacuuacga gagcaaaauu ugaagaauua aacauggacc uauuuagaag cacaaugaaa     1020

ccuguacaaa aagugcucga agauucagac cuaaaaaaaa gcgacauaga ugagauuguc     1080

uuaguaggag gaaguacaag aauuccaaaa auccaacaac uaguaaaaga auuuuucaau     1140

ggaaaagaac cuaguagagg aauaaaccca gacgaagcag uagcauaugg agcugcagua     1200

caagcuggag uucuaagugg cgaccaagac acaggagacu uaguauuacu agacguaugu     1260

ccguuaacau uaggaauaga aacaguagga ggaguaauga ccaaauugau accuaggaac     1320

acuguuguac caacgaaaaa aucacaaaua uuuaguacag caucagauaa ccaaccaacu     1380

guaacuauaa aaguauacga aggagaaagg ccucuaacaa aagacaauca ccuucuggga     1440

accuuugauc ucacaggaau accaccagca ccacggggag uaccgcaaau agaaguaaca     1500

uucgaaauag acgucaacgg uauucuaaga guaacggccg aagauaaagg aacaggaaac     1560

aagaauaaga uaacuauuac aaaugaccaa aaucgauuaa cuccagaaga aauagaacga     1620

auggucaacg acgcagaaaa auuugccgaa gaagauaaaa aauuaaaaga gagaauagau     1680

acucgaaacg aacuagaaag uuacgccuac ucacucaaaa accaaaucgg ggauaaagaa     1740

aaguuaggag guaaauuauc aagugaagau aaagaaacaa uggaaaaagc agucgaagaa     1800

aaaauugaau ggcuagaauc acaccaagac gcagauauag aagauuucaa agcaaaaaaa     1860

aaagaauuag aagaaauugu acaacccaua auuaguaaau uauauggaag ugcagggcca     1920

ccaccaacag gcgaagaaga cacagcagaa aaagaugaau uauaa                     1965


<210>  752
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  752
augcaagcac caagagaacu agcgguagga auagauuuag gaacaacuua cucaugugua       60

ggaguauuuc aacaaggaag aguagaaaua uuagcaaaug accaaggaaa uagaacaaca      120

cccucauacg uagccuuuac agacaccgaa cgauuaguag gagaugcagc aaaaagccaa      180

gcagcacuca acccacauaa uacggucuuu gacgcaaaaa gauuaauagg ccgaaaauuu      240

gcggauacua caguacaaag ugauaugaaa cacuggcccu uucgaguagu aucugaagga      300

ggaaaaccga agguaagagu auguuaucga ggagaagaca aaacauucua uccagaagaa      360

auaucuucua ugguauuguc gaaaaugaaa gaaacggcug aagcguaucu aggacaacca      420

guaaaacaug caguaauaac uguaccagcu uacuuuaaug auagccagag acaagcaaca      480

aaagaugcag gagccauagc aggauuaaau guauugagga uaauaaauga accaacugca      540

gccgcaauag cauacggguu agaccgaaga ggagccggug aaagaaaugu cuuaauauuu      600

gauuugggcg gaggaacauu ugauguaagu guauuaucaa uagacgcagg aguuuuugaa      660

gucaaagcaa cggcaggaga cacacauuua ggaggggaag acuuugauaa uaggcuagua      720

aaucauuuca uggaagaauu ucgaagaaaa cacggaaaag auuuaucugg aaauaaacga      780

gcuuuaagaa gguuaagaac agccugugaa agagcaaaaa gaacauuauc aucaaguaca      840

caagcaacau uagaaauuga cucacucuuc gaaggagucg acuucuauac aucaauaaca      900

cgagcaagau uugaagaacu augcucagau cuauuucgau caacauuaga accaguggaa      960

aaagcauugc gggaugcgaa auuagacaaa gcacaaauac augacguagu uuuaguaggc     1020

ggcucaacaa gaauaccaaa agugcaaaaa cuauuacaag auuucuucaa cgggaaagaa     1080

uuaaacaaau caauuaaucc ggaugaagcu guagcuuaug gagcagcagu ucaagccgcc     1140

gucuuaaugg gagacaaaug cgaaaaaguu caagauuuau uacuacuaga uguggcacca     1200

cucucucuug gucucgaaac agcgggagga guuaugacua cguuaaucca aagaaaugca     1260

acaauuccaa caaaacaaac ccagacauuc acaacauacu cugauaauca accaggaguc     1320

uuuauacaag uuuacgaagg cgaacgagca augacaaaag auaauaauuu auugggaaga     1380

uuugaacuuu caggaauacc cccagcaccu agaggaguac cucaaauaga aguaaccuuc     1440

gacauagacg cuaauggaau acuuagcgua acugcaacug auagaaguac aggaaaagca     1500

aacaaaauaa caauaacaaa cgauaaaggc cgacuaagca aagaagaagu agaaagaaug     1560

guacaugaag cugaacaaua caaagccgaa gaugaagcac aacgagauag aguugcagcu     1620

aaaaauaguc uagaggcaca uguauuucau guaaaaggca gccuacaaga agagagcuua     1680

agagacaaaa uaccagaaga agacagaaga aaaaugcaag auaaguguag agaaguauug     1740

gcaugguuag aacauaauca auuagcagaa aaagaagaau augaacauca aaaacgagaa     1800

uuagaacaaa uaugucgacc aauauuuuca agguuauaug gaggcccagg aguaccaggg     1860

ggaaguucau gugguacaca agcaagacaa ggugauccgu caacaggacc aaucaucgaa     1920

gaaguagacu aa                                                         1932


<210>  753
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__P48741__HsHSPA7

<400>  753
augcaagcac caagagaauu agcuguagga auagacuuag gaacaacaua uuccugugua       60

ggaguauuuc aacaaggaag aguagaaauu uuagcaaaug aucaaggaaa uagaacaaca      120

ccaucauaug uagcauuuac ugauaccgaa agauuagucg gagaugcagc aaagucacaa      180

gcagcauuaa auccucacaa uacaguuuuu gaugcaaaaa gauuaauagg aagaaaauuc      240

gcugauacaa caguacaaag cgacaugaaa cauuggccau uccaaguugu aagcgaaggu      300

ggaaaaccaa aaguacgagu auguuauaga ggagaagaca aaacauucua ccccgaagaa      360

auaucaagua ugguucuauc aaaaaugaaa gaaacagcag aagcauauuu aggacaacca      420

guuaaacaug caguaauaac cguuccaaca uauuuuagca auagucaaag acaagcaacu      480

aaagaugcag gagcaauagc aggacuuaaa guacugccaa uaauaaauga agcaacagca      540

gcagcaauag ccuauggccu agacagaaga ggagcuggaa aaagaaacgu auuaauauuu      600

gauuuaggag gaggaacuuu ugauguaagu guauuaagua uugacgcagg cguuuuugaa      660

guaaaagcaa cugcugguga uacucacuug gguggagaag auuuugauaa uagauuagua      720

aaucauuuua uggaagaauu uagaagaaaa cacggaaaag aucuaagugg aaauaaaagg      780

gcauugagaa gauuaagaac agcaugugaa agagcaaaaa gaacaccuag cucaaguaca      840

caagcaacgc uagaaauaga uucauuauuc gaaggaguag auuuuuauaa aucaaucaca      900

agggcaagau uugaagaauu augcagugac uuauucagga gcacauuaga accaguagaa      960

aaagcauuaa gagaugcaaa auuagauaaa gcacaaauac augauuuugu gcuaggaggg     1020

ggauuacauu cacauccaca aggagcagaa guugcagcag gauuauuaca aagacaagga     1080

gcagaacaag aacaccaacc auaa                                            1104


<210>  754
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  754
augagcaaag ggccagcagu aggaauagau uuagguacca ccuacagcug uguaggagua       60

uuccaacacg gaaaagugga aauaauagca aaugaccaag gcaauaggac aacaccauca      120

uacguugcau ucacagauac cgagcgacua auuggagaug cagcuaaaaa ucaaguagca      180

augaauccaa caaauacggu auuugacgca aaaagacuaa uaggcaggag guuugaugac      240

gcaguuguac aaagcgauau gaaacacugg ccauuuaugg uaguaaauga ugcuggaaga      300

ccaaaaguac aaguagaaua caaaggcgaa acuaaaaguu ucuaccccga agaaguaucu      360

ucaaugguau uaacaaaaau gaaagaaauc gcagaagcau acuuaggaaa aacgguuaca      420

aacgcaguag uaacaguacc agcauauuuu aacgacuccc aaaggcaagc aacaaaagac      480

gcugggacaa uugccgggcu uaauguauua agaaucauaa augaaccaac agcagcagca      540

auagccuacg gauuagauaa gaaaguaggu gcagaaagaa acguauuaau auuugacuua      600

ggcgguggaa cauuugaugu aucaauauua acaauagaag acggaauauu ugaaguaaaa      660

ucuacagcug gagacacaca ccuaggagga gaagauuucg auaacagaau gguaaaucau      720

uuuauagccg aauuuaaaag gaaacauaag aaagauauaa gugaaaauaa aagagcagua      780

agaagauuaa gaacagcaug cgagcgagcg aaaaggacuu uaucaucgag cacacaagca      840

agcauagaaa uugauagccu auaugaaggu auagacuuuu acacaucaau aacaagagcc      900

cgauucgaag aauuaaacgc agaucuauuu agaggaacgu uagacccagu agaaaaagca      960

uuaagagaug caaaauuaga uaaaagccaa auacaugaca ucguauuggu uggaggaucu     1020

acaagaauac cuaaaauaca aaaauuacua caagacuucu uuaacggcaa agaauuaaac     1080

aaaucaauaa auccagacga agcaguagcg uauggugcgg cgguacaagc cgcuauauua     1140

uccggagaca aaagugaaaa cguacaagau cuacuauuac uagacguaac accccuauca     1200

uuaggaauug aaacagcagg aggaguaaug acaguuuuaa uaaaaagaaa uacaacaaua     1260

ccaacuaaac aaacccaaac auuuacaacu uacagugaca aucaaccagg agugcucaua     1320

caaguuuacg aaggagaacg agcaaugaca aaagacaaca aucuauuagg aaaauuugaa     1380

cuaaccggaa uaccaccagc accuagaggc gugccacaaa uagaagucac auuugacaua     1440

gaugcaaaug gaauacuaaa cgucagcgca gucgauaaau caacaggaaa agaaaacaaa     1500

auaaccauaa caaacgacaa aggacgccug agcaaagaag auaucgaacg aaugguacaa     1560

gaagcagaaa aauauaaagc ggaggacgaa aaacaacgag acaaaguaag caguaaaaac     1620

agcuuagaau cauaugcauu uaauaugaaa gcaacuguag aagacgaaaa auuacaagga     1680

aaaauaaacg augaagauaa acagaaaaua cuagacaaau guaacgagau aauaaauugg     1740

cuggacaaaa aucaaacggc agaaaaagaa gaauuugaac aucaacaaaa agagcuugaa     1800

aaaguuugua auccaauaau aacaaaacua uaucaaagug caggaggaau gccaggagga     1860

augcccggag gauucccugg aggaggcgca cccccaagug gaggagccag uucaggccca     1920

acaauagaag aaguagauua g                                               1941


<210>  755
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  755
augauaucag caagcagagc agcagcagca agacuugugg gagcagcagc aucaagagga       60

ccuacagcag caaggcauca agauucgugg aauggguuaa gccaugaggc guuuagacuu      120

gugucuagga gagauuacgc cagcgaagca auuaaaggug cgguuguagg aauagaucua      180

ggaacgacaa acucaugugu agcagucaug gaaggaaaac aagcaaaagu gcuagaaaau      240

gcagaaggcg caagaacaac accaucagua guugcauuua cagcagaugg agaaagguua      300

guugguaugc cagcaaaaag acaagcagua acaaauccga acaauacauu uuacgcuaca      360

aaaagguuaa uaggaagaag auacgaugac ccagaagugc aaaaagauau uaaaaaugua      420

ccuuuuaaaa uagucagagc aucuaauggu gaugcauggg uagaggccca cggaaaacuc      480

uacucuccaa gucaaauagg agccuucgua uuaaugaaga ugaaagaaac agcugaaaau      540

uauuuaggac acacagcgaa aaaugcagua auaacgguac cagcauacuu caacgacagu      600

caaagacagg caacaaaaga cgcaggacaa auaaguggau uaaacguauu aagaguaaua      660

aaugaaccua cagcagcagc auuagcauau ggccuagaua aaucagaaga caaaguaaua      720

gcgguauaug auuuaggcgg aggaacauuu gacauuucaa uauuagagau acaaaaaggu      780

guauuugaag uuaaaaguac aaauggugac acauuuuugg gaggagaaga uuucgaucaa      840

gcacuacuuc gacauauagu uaaagaguuu aaaagagaaa cagggguaga ucucacuaaa      900

gauaauaugg cauugcaaag gguaagggaa gcagcugaaa aagcaaagug cgagcuaagc      960

ucaucuguac aaacggauau uaaucuacca uauuuaacaa uggacagcuc agguccaaaa     1020

caucucaaua ugaaauuaac aagagcucaa uucgaaggaa uaguaacgga cuuaauaaga     1080

agaacuauag caccauguca aaaagcuaug caggaugcgg aagugagcaa gagugacaua     1140

ggagaaguua ucuugguagg uggaaugaca agaaugccaa aaguucaaca gacaguacaa     1200

gaucuauucg ggagagcucc uaguaaagcu guuaauccag acgaagccgu agccauagga     1260

gcagcaauac aaggaggagu auuagcagga gauguaacug auguacuacu auuagaugua     1320

acaccguuga gccuuggaau agaaacuuua ggaggagugu ucacuaaauu aaucaauaga     1380

aauacaacga uaccuacgaa gaaaucacaa guauucagua cagcagccga ugggcaaaca     1440

caaguagaaa uaaaagucug ccaaggagaa agagagaugg caggagauaa uaaauuguua     1500

gggcaauuua cauuaauagg uauaccucca gcaccgagag gaguaccuca gauagaaguu     1560

acauucgaua uagaugcaaa ugguauaguu cauguaucag caaaagacaa aggaacugga     1620

agagaacaac aaauagugau acaaagcagu ggaggacuaa guaaagauga uauagaaaac     1680

augguuaaaa acgcggaaaa auaugcagaa gaagauagaa gaaagaaaga gagaguagaa     1740

gcaguuaaca uggcugaagg aauaauacau gacacugaaa caaaaaugga agaauuuaaa     1800

gaucagcuac cagcagauga auguaauaaa cuaaaagagg aaauaaguaa aaugagagaa     1860

uuguuagcua gaaaagacag ugagacugga gaaaauauua gacaagcagc aagcucauua     1920

caacaagcaa gccucaaauu auuugagaug gcauauaaga aaauggcauc agaaagggaa     1980

ggauccggau caagcggaac gggagaacaa aaagaagauc aaaaagaaga aaaacaauag     2040


<210>  756
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  756
auggcagaca aagaagcagg cggaagugau gggccaagag aaacagcacc aacaucagca       60

uacaguucac cagcaagaag ccuaggagac acaggaauaa ccccauuaag uccaucgcac      120

auuguaaacg acacagacuc caacguaagc gaacaacaaa guuuccuagu aguaguagcu      180

guagauuuug gaaccacauc aucaggauac gcauacucau uuacaaaaga accugaaugu      240

auacauguca ugagaagaug ggaaggcgga gauccuggag uaaguaauca aaaaacucca      300

acaacaauac uucucacacc agaacgaaaa uuccacucau uuggauaugc agccagagac      360

uuuuaccacg auuuagaucc aaaugaagca aaacaauggu uauaccuaga aaaauucaaa      420

augaaacuuc auaccacugg agauuuaaca auggacacag accuaacagc agccaaugga      480

aaaaaaguaa aagcacuaga gauauuugca uacgcacuac aauacuuuaa agaacaagca      540

cuaaaagaau uaagcgacca agcagguucc gaauuugaaa auucagacgu aagaugggua      600

auaacagucc ccgcaauaug gaaacaaccc gccaagcaau uuaugagaca ggcagcauac      660

caagcgggac uagccucccc agaaaacuca gaacaacuaa uuauagcacu ugaaccagag      720

gcagcgucaa uauauuguag aaaacuacga uuacaucaaa ugauagaauu aaguucaaaa      780

gcagcaguaa auggauacuc aggaucagau acagugggag caggauuuac acaagcuaaa      840

gaacauauua gaagaaacag acaaagcaga acauuucuug uagaaaacgu cauaggagaa      900

auaugguccg aacuagaaga aggagauaaa uauguaguag uugacagcgg aggaggaaca      960

guagaucuaa cuguccauca aaucagacua cccgaagggc acuuaaagga acuauacaaa     1020

gcaacgggag gcccauacgg cucauuagga guugacuacg aauucgaaaa auuauuauac     1080

aaaauauucg gagaagauuu uauagaacaa uuuaaaauca aaaggccugc agcaugggua     1140

gauuuaauga uagcauuuga aagcagaaaa agagccgcag cacccgauag aacaaaccca     1200

cuaaauauaa cacuaccguu cucauuuaua gauuacuaua aaaaauuuag aggacauucg     1260

guagaacaug cacuaagaaa aagcaacguu gacuuuguca aauggagcag ucaaggaaug     1320

uuacggauga gcccagaugc aaugaaugca cuauucaaac caacaauaga uaguaucaua     1380

gaacauuuaa gagauuuauu ucaaaaacca gaagucagua caguaaaauu ccuauucuua     1440

guaggcggau ucgcagaagc accccuauua caacaagccg uacaagcagc auucggagau     1500

caauguagaa uaauaauccc acaagauguc ggacucacaa uacucaaagg agcaguucua     1560

uucggacucg acccagcagu aauuaaagua agaagaucac cacuuaccua ugguguuggu     1620

guauuaaaua gauauguaga aggaaaacac ccuccagaaa aauuauuagu aaaagaugga     1680

acaagauggu gcacugacgu auuugauaaa uuuauuucgg cagaccaauc aguagcucua     1740

ggugaacuug uaaaacgauc cuauacaccu gcaaaaccau cacaacuagu cauaguaaua     1800

aauauauacu ccucagaaca cgauaauguc ucauuuauca cugacccagg aguaaaaaaa     1860

uguggcacau uaagauuaga uuugacaggu acaaguggua cugcaguacc cgcacgaaga     1920

gaaauccaga cauuaaugca auuuggcgac acagaaauca aagccacagc aauagacaua     1980

gccacaucua aaucaguaaa aguaggaaua gacuucuuaa auuauuaa                  2028


<210>  757
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  757
augcuugcag uuccagaaau gggacuacaa ggacuauaua uaggcaguuc accagaacga       60

aguccgguac ccaguccacc gggaucacca aggacacaag aaaguugcgg aauagcaccu      120

cuaacaccua gccaaucacc uaaaccugaa gugagagcac cacaacaagc gaguuucucg      180

guuguaguag caauagauuu cggaacaaca ucaagugguu augcauuuuc auuugcuuca      240

gauccagaag cuauacauau gaugcgaaaa ugggaaggag gcgauccugg cguagcacau      300

cagaaaaccc cuacuugucu auugcuaaca ccagaaggag cauuucauag uuuuggauau      360

accgcucgag auuacuauca ugacuuagau ccagaagaag caagggauug guuauacuuu      420

gaaaaauuua aaaugaaaau acauagugcc acggaucuaa cauuaaaaac acaauuagaa      480

gcaguaaaug gaaaaacaau gccagcauua gaaguauuug cacacgcauu gagauucuuu      540

cgcgaacaug ccuuacaaga acuacgcgaa caauccccuu ccuuaccaga aaaggauacu      600

guacgauggg uauuaacagu ccccgcuaua uggaaacaac cggcuaaaca auuuaugaga      660

gaagcagcau auuuggcugg ccuagucagc cgggaaaacg cugaacaauu acuaauagca      720

uuagaaccag aagcugcaag cguauacugu agaaaacuaa gacuucauca auuacuagau      780

cuaagcggaa gggcaccugg aggagggcga uuaggagaaa gaagaucuau agauucauca      840

uuuagacaag cuagagaaca auuaagaaga ucacgucacu caagaacauu ucuaguugaa      900

ucagguguag gcgaacuuug ggcagaaaug caagcaggag acagauaugu aguggcugac      960

ugcggagggg guacaguuga ccuaacagua caucaauuag aacaaccaca cggaacacua     1020

aaagaauuau auaaggcuuc aggaggacca uacggggcag uaggaguuga ucuagcuuuu     1080

gaacaacuac uuugucgaau auucggugaa gauuuuauag caacauuuaa aaggcaaaga     1140

ccugcugcau ggguagaucu aacuauagca uucgaggcaa gaaaacgaac agcaggacca     1200

cauagagcug gugcuuuaaa cauuucauua ccauuuucau ucauagauuu uuacagaaaa     1260

caaagaggac auaauguaga aacagcauua agaagaaguu caguaaauuu uguaaaaugg     1320

ucuagucaag gaaugcuaag aaugucaugc gaagcuauga acgaacuauu ucaacccaca     1380

guauccggua uaauacaaca uauagaagca cuauuagcua gaccugaagu acaaggagua     1440

aaauuauuau uuuuaguagg aggauucgca gaaucagcug uguuacaaca ugcugugcaa     1500

gcagcguugg gcgcuagagg ucuaagagua guaguuccuc acgauguagg acuaacaaua     1560

cuaaaaggag caguauuauu cggccaagcg ccuggaguag uucgaguaag aagaucucca     1620

uuaacauaug gugugggagu auuaaauaga uucgugccag guagacaucc accagagaag     1680

cuauuaguaa gagauggcag gagguggugu acugaugucu ucgaaagguu uguugcagcc     1740

gaacaaagcg uugcacuagg agaagaaguu agaagaucau acuguccagc acggccagga     1800

caaagaagag ugcuaauuaa cuuauauugu ugcgcagcag aagaugcaag auuuauuaca     1860

gacccaggug uaagaaagug uggagcccuc aguuuagaac uugaaccagc ugauugcggc     1920

caagauacag caggcgcacc cccaggcaga cgagaaauaa gagcggcaau gcaauuugga     1980

gauacagaaa uaaaaguuac agcuguagau guaagcacaa acagaagugu uagagcauca     2040

auagacuuuc uaaguaacua a                                               2061


<210>  758
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  758
auggcuagag aaaugacaau acucggcucu gcaguauuaa ccuuacuauu agcaggauau       60

uuagcacaac aauaccuucc cuuaccaaca ccaaaaguaa uagguauaga ucucgguaca      120

acauauuguu ccgucggagu uuucuuucca ggaaccggaa aaguuaaagu uauaccagac      180

gaaaauggac acauauccau accaaguaug guaaguuuua ccgacaacga uguauauguc      240

gguuacgaaa gcguagaauu agcagauagu aauccacaaa acacaauaua ugacgcaaaa      300

agauucauag gaaaaaucuu caccgcagaa gaacuggaag cagaaauagg aagauaucca      360

uucaaaguac uaaauaaaaa uggaauggua gaauucucag uaacuuccaa ugaaacaaua      420

acaguaucac cagaauaugu cggcucaaga uuauuauuaa aauuaaaaga aauggcagaa      480

gcauacuuag gaaugccagu agcaaacgca guaaucucag uaccagccga auucgauuua      540

aaacaaagaa auuccacuau agaagcagca aaucuagcag gucuuaaaau auuaagagua      600

auaaaugaac ccacagcagc agcaauggca uauggacuac acaaagcaga uguuuuucac      660

guacuaguga uagauuuagg aggcggcaca uuagacguaa gucuacucaa uaaacaaggc      720

gguauguuuc uaacaagagc caugagugga aacaacaaau uaggaggaca agacuuuaac      780

caaagacuac uacaauauuu auacaaacaa auuuaccaaa cauauggauu cgucccauca      840

agaaaagagg aaauccacag acuaaggcaa gcaguagaga uggucaaacu aaacuuaaca      900

uuacaucaau cagcacaacu aucagucuua uuaacaguag aagagcaaga uagaaaagaa      960

ccucacucca gugacacaga acucccuaaa gauaaacuau caucagcaga ugaccaccga     1020

gucaacagug gauucggaag aggccuaagu gacaaaaaaa gcggagaauc acaaguauua     1080

uuugaaacug aaauuagcag aaaacuauuu gauacauuaa augaagaccu auuucaaaaa     1140

auacuaguac caauacaaca aguacucaaa gaaggacauu uagaaaaaac agaaauagac     1200

gaaguaguac uaguaggagg aagcacacga auuccuagaa uaagacaagu aauacaagaa     1260

uuuuucggca aagacccuaa uacaucagua gacccagauc uagccgucgu aacaggagua     1320

gcaauacagg caggaauaga uggaggaagc uggccacuuc aagucagugc cuuagaaauc     1380

ccaaacaaac auuuacaaaa aaccaauuuc aacuaa                               1416


<210>  759
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  759
auggcagcaa uaggaguaca ccuaggaugu acaucagcau guguagccgu auauaaagau       60

gguagagcag gaguuguggc caaugaugcc ggagauagag uaacuccugc aguaguugca      120

uacagcgaaa augaagagau aguuggacua gcugcaaaac aaagcagaau aagaaauaua      180

aguaauacag uaaugaaagu caaacaaaua uuaggaagau caaguucaga cccucaagcu      240

caaaaauaca uugcugaaag caaaugucua guaauagaga aaaauggaaa acuaagauau      300

gaaauugaua cgggugaaga aacuaaauuc guaaacccag aagauguagc aagacuaaua      360

uuuaguaaaa ugaaagaaac agcucauuca guauuaggau cagacgcaaa ugacguagua      420

auaacuguac cauucgauuu uggagaaaaa caaaagaacg cuuuaggaga agcggcuaga      480

gcagcagguu uuaauguauu aagacuaaua caugaaccau ccgcugcacu auuagcauac      540

ggaauaggac aagauagucc aacagguaaa ucaaauaucc uaguauucaa auuaggagga      600

acaucauuau cguuaucagu aauggaagua aauaguggga uauauagagu auugagcaca      660

aauacagaug auaauauagg cggagcacau uuuacagaaa cucuagcaca auaucuagca      720

agugaauuuc aaagaaguuu uaaacaugau guucgaggaa augcaagagc aaugaugaaa      780

uuaacaaauu cagcggaagu agcaaaacac ucauuaagca cguuagguag ugcaaauugu      840

uucuuagaua guuuauauga aggacaagau uuugauugua auguaucacg agcccgauuu      900

gaauuauuau guagcccucu auuuaauaaa uguauagaag caauaagggg auuacucgau      960

caaaauggau ucacagcuga ugauauaaau aaaguaguau uauguggagg uucaaguaga     1020

auaccuaaau uacaacaacu aauaaaagac uuauuuccag caguagaacu gcuaaauagu     1080

auaccgccag acgaaguaau accaauagga gcagcaauug aagccggaau acuaauugga     1140

aaagaaaauc uauuaguaga agacagccuu augauagaau guagugcaag agacauacuc     1200

gucaaaggcg uagaugaauc cggagcaagu agauucacug uauuauuccc aucaggaacg     1260

ccacuaccag caagaagaca acauacacua caagcaccag gaagcauauc aaguguaugu     1320

cuagaacuau augaaucaga cgggaaaaau agcgcaaaag aagaaacaaa auuugcacaa     1380

guaguauuac aagauuuaga caagaaagaa aauggauuaa gagauauauu agcaguauua     1440

acuaugaaac gagacggaag ucuacaugua acauguacag aucaagagac aggaaaaugu     1500

gaagcgauau caauagaaau ugcuagcuaa                                      1530


<210>  760
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  760
augucaguag uaggacuuga uguaggauca caaucauguu auauagcagu agcacgagca       60

ggagguauag aaacaauagc aaaugaauuc agcgauagau guacaccuuc agucauaucu      120

uucggaucaa agaaucgaac cauuggcgua gccgcaaaaa accaacaaau cacgcacgcu      180

aacaauacag uaucaaacuu uaaaagauuu cacggucgag cguuuaauga ccccuucauu      240

caaaaagaaa aagaaaacuu aagcuaugac cuuguaccac uuaaaaaugg aggaguaggc      300

auuaaaguaa uguacauggg agaagaacac cuauuuagug uagaacaaau caccgcgaug      360

cuacuaacaa aacuaaaaga aacagcagag aauagccuaa aaaaaccagu uacugacugc      420

guaauaagug uaccaucuuu cuuuaccgac gcagaaagac gguccguucu agaugcagcc      480

caaauaguag gauuaaacug ucucagacua augaaugaua ugacugcagu ggcucuaaau      540

uauggaauau auaaacaaga cuugccauca cuagaugaaa aaccaagaau cguagucuuc      600

gucgauaugg gccauagcgc auuucaaguu ucagcaugug cuuucaacaa aggaaaacug      660

aaaguucuag gaacggcauu cgauccauuu cuagggggaa aaaauuuuga cgaaaaauua      720

guagaacacu uuugcgccga auucaaaaca aaauacaaac uagacgcaaa aaguaaaaua      780

agagcauuau ugagauuaua ccaagaaugc gaaaaacuaa aaaaauuaau gagcuccaac      840

ucaacagacu ugccauuaaa cauagaaugc uucaugaaug auaaagacgu auccgguaaa      900

augaauagau cccaguucga ggaacuaugu gccgaacuac uucaaaaaau agaaguacca      960

uuauacucac uauuagaaca aacucaccua aaagucgaag acguaagugc aguagaaauu     1020

guagguggag caacaagaau accggcugua aaagaaagaa uagcaaaauu cuuuggaaaa     1080

gauauaucaa caacauuaaa cgccgaugaa gccguagcua gagggugcgc acuucaaugc     1140

gccauauuau caccagcguu uaaagucaga gaauucagug uuaccgaugc aguaccauuc     1200

ccaauaaguu uaauauggaa ccaugacuca gaagacaccg aaggaguuca ugaaguauuu     1260

agccgaaacc acgccgcacc auuuaguaaa guauuaacau uucuaagacg ugguccauuu     1320

gagcuugaag cauuuuauuc ugauccacaa ggaguaccau acccagaagc aaaaauaggc     1380

agauuugucg uacaaaacgu aucggcacaa aaagauggag aaaaaucacg agucaaagua     1440

aaggugagag uaaacacaca uggaauauuc acaauaagua cagccagcau gguggaaaaa     1500

guuccaacag aagaaaacga aaugagcagc gaagcagaua uggaaugucu aaaccaaaga     1560

ccgccagaaa acccagacac agauaagaau guccaacaag acaacucuga agcaggcacu     1620

caaccacaag uucaaacaga ugcacaacaa acuucacaau caccaccguc uccagaauua     1680

accagugaag aaaacaaaau acccgacgca gauaaagcaa acgaaaaaaa aguagaccaa     1740

ccaccagaag caaagaaacc aaaaauuaaa gucgugaacg uagaauuacc aauagaagca     1800

aaucuaguau ggcaauuagg caaagaccua uuaaauaugu auaucgagac cgaagguaaa     1860

augauaaugc aagacaaauu agagaaagaa cgaaaugaug caaaaaaugc aguagaagaa     1920

uauguauaug aauuuagaga uaaacuaugu ggaccguacg aaaaauuuau augugaacaa     1980

gaccaucaaa auuuucuacg acuucuaacu gagacagaag acuggcuaua cgaagaagga     2040

gaagaucaag caaaacaagc guauguagac aaacuagaag aauuaaugaa gauagguaca     2100

ccaguaaaag uacgauucca agaagcagaa gagagaccaa aaauguuuga agaacugggu     2160

caaagauuac aacacuaugc aaaaaucgcc gcagacuuuc gaaacaaaga cgaaaaguau     2220

aaucauauag augaaucaga aaugaaaaaa gucgaaaaaa gugucaacga agugauggag     2280

uggaugaaua acguuaugaa ugcacaagcc aaaaaaagcc uagaucaaga uccuguagua     2340

agagcacaag agaucaaaac caaaauaaaa gaacuaaaua acaccugcga gccagugguu     2400

acccagccaa aaccaaaaau agaaaguccc aaauuagaga gaacccccaa uggaccaaau     2460

auagauaaaa aagaagaaga ccuagaggau aaaaauaacu ucggagccga accaccacac     2520

caaaaugggg aauguuaccc caacgaaaaa aauaguguaa acauggauuu agacuaa        2577


<210>  761
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  761
auggcugaua aagucagacg acaacggcca agaagaaggg uaugcugggc acugguagca       60

guucugcuag ccgauuuauu agcguuauca gauacccuag cuguaaugag cguagacuua      120

ggcagugaaa guaugaaagu ggcaauagua aaaccaggag uacccaugga gauuguuuua      180

aauaaagaau caagaagaaa gacgccagua auaguaacgc uaaaagagaa cgaaagauuc      240

uuuggagacu cagcagcaag uauggcaauu aaaaacccaa aagcaacccu gagauacuuu      300

caacaucugu ugggcaaaca agcagacaac ccacauguag cgcuauacca agcgagguuu      360

ccugaacacg aacuaacauu cgacccacaa agacaaacag uacacuucca aauaucuuca      420

caacuccaau uuucaccuga ggaaguacuu ggaauggucu uaaacuacag ucgaaguuug      480

gcggaagauu uugccgaaca accuauaaaa gaugcaguaa uaacaguacc uguauucuuu      540

aaucaagccg agaggagagc uguauuacaa gcugcaagaa uggcuggacu uaaaguacua      600

caacucauaa augacaauac agcuacugca cuaucauaug guguuuuuag aagaaaagac      660

auaaacacaa cugcacaaaa uaucauguuu uacgauaugg gaagcggaag cacagucugc      720

acuauaguca ccuaucagau ggugaaaaca aaagaagcag gaaugcagcc ucaauuacaa      780

auaagaggag uagguuuuga cagaacgcug gguggauuag aaauggaacu gagauuaaga      840

gaacgauugg caggacuauu caaugagcaa cgaaaggguc agagagcuaa agacguuaga      900

gaaaauccuc gcgcaauggc uaaacuuuua cgcgaagcaa auagauuaaa gacaguacuu      960

agugcaaacg cagaccauau ggcucaaaua gaaggacuaa uggaugacgu agacuuuaaa     1020

gcaaaaguaa cacgaguaga guucgaagaa cuaugugcag aucucuuuga aagaguaccu     1080

gguccaguac aacaagcucu acaaagugcu gaaaugucuu uagacgaaau ugaacaagua     1140

auauuggucg gcggagcaac acgaguuccu agaguacaag aaguauugcu uaaggcagua     1200

ggaaaagaag aacuagggaa aaauauaaac gcugacgaag cagcagcaau gggagccguu     1260

uaccaagcgg cagcacuaag caaggcuuuu aaaguuaaac cauuuguagu aagagaugca     1320

guuguauauc caauuuuagu agaauuuacu cgagaaguag aagaagaacc agggauacac     1380

ucacuaaaac acaacaaaag aguacucuuu agcaggaugg gaccguaucc acaacguaaa     1440

gucauaacau uuaacagaua uucucaugau uuuaauuucc auauaaacua cggagacuua     1500

ggcuuuuuag guccagaaga ucuaagggua uuugguucac aaaaucucac aacgguuaaa     1560

cuaaaagggg uaggagauag uuucaagaaa uacccagacu augaaucuaa aggaauaaaa     1620

gcacauuuua aucuagauga aaguggggua uugagucuag accgagucga gagcguauuc     1680

gaaacucugg uugaagauag ugccgaagag gaaucaaccu ugacuaaacu agguaauacg     1740

auaagcagcu uauucggagg uggcacaaca ccagaugcaa aagaaaaugg aacagacaca     1800

guacaggaag aagaagaaag cccggcagag ggcucaaaag augaaccugg ggaacaagua     1860

gaguuaaaag aagaagcaga agcaccagug gaagacgguu cgcaaccacc ucccccagag     1920

ccaaaaggug augcaacacc agaaggcgaa aaagcaacag aaaaagaaaa uggggauaaa     1980

ucagaagcac aaaagccaag ugaaaaagca gaagcuggac cagaaggagu ugcuccugca     2040

ccagaaggag aaaagaaaca aaaacccgca cgcaaaagaa gaaugguaga ggaaauaggu     2100

gucgagcuag uaguauuaga ucuaccagau cucccagaag acaaauuggc acaaagugua     2160

caaaaacugc aggacuuaac cuuaagagac uuagaaaaac aagaaaggga aaaagcugca     2220

aauucuuugg aagcauucau auucgaaaca caggacaaau uauaucaacc cgaauaucag     2280

gaaguaucca cagaagaaca aagagaagaa auaucaggaa aacucucagc agcaucaacg     2340

ugguuggaag augaaggagu aggugcaaca acaguaaugu uaaaagaaaa auuagcagaa     2400

cuaaggaaac ugugccaagg auuauuuuuc agagucgaag aaagaaagaa auggccagaa     2460

cgguuaucug cauuagauaa uuuacuaaac cacucuagua uguuucuaaa aggggccaga     2520

uuaauaccag aaauggauca aauuuuuacu gaaguagaaa ugacaacacu agaaaaagua     2580

aucaacgaaa caugggcaug gaaaaaugca acuuuagcag aacaagcaaa auuaccggca     2640

acagaaaaac cagucuuacu aucaaaagac auagaagcga aaaugauggc auuagacaga     2700

gaaguccaau accuacuaaa caaagcaaag uucacaaaac ccagaccgcg gccaaaagau     2760

aaaaacggaa cccgagccga gccaccacua aaugcaagcg caagugauca aggggagaag     2820

guaauaccgc cugcaggaca aacagaagac gcagaaccaa ucuccgaacc agaaaaagua     2880

gaaacaggau cggaaccugg agauacagaa ccccuagaau uaggaggacc uggagcugag     2940

ccagaacaaa aagaacaaag uacaggacaa aaacgaccuc uuaaaaauga cgaacuauaa     3000


<210>  762
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  762
augccagaag aaacccaaac acaagaccaa cccauggaag aagaggaagu agaaacauuc       60

gcuuuccaag cagaaauugc acaauuaaug agucuaauua uaaacacauu cuacucaaac      120

aaagaaauau uuuuacgcga acuaauaagc aacucaagcg augcauuaga uaaaauuaga      180

uaugaaucgu uaacagaucc aagcaaauua gacucaggaa aagaauuaca cauaaaucuu      240

aucccaaaca aacaagauag aacacuuacc auagucgaca ccggaauagg aaugacaaaa      300

gcugaccuaa uaaacaauuu agguacaaua gcaaaaucgg guaccaaagc auucauggaa      360

gcacuacaag caggugccga caucucgaug auaggacaau uuggaguagg auucuacagc      420

gcauaccuag uagcagagaa aguaacaguu auaacaaagc acaacgacga cgaacaauac      480

gccugggaau caagugcagg aggaucauuc acaguaagaa cagacacagg ugaaccaaug      540

ggcagaggua cgaaaguaau acuucaucuu aaagaagacc aaacagaaua ccuagaggaa      600

agaagaauca aagaaauagu aaaaaaacac ucacaauuca uaggauaucc aauaacacuc      660

uuuguagaga aagaaagaga caaagaaguc agugacgaug aagcagagga aaaagaagau      720

aaagaagaag aaaaagaaaa agaagaaaaa gaaagugaag acaaaccaga aauagaagac      780

guaggaucgg augaggagga agaaaaaaaa gauggagaca aaaaaaaaaa gaaaaaaaua      840

aaagaaaaau acauagauca agaagaacug aacaaaacca aaccaauaug gacaaggaac      900

cccgacgaca ucacaaacga agaauacgga gaauuuuaca aaucacuuac aaaugacugg      960

gaagaccacc ucgccgucaa acacuuuagc guagaagguc aauuagaauu cagagcccua     1020

cuguuuguac cuagaagagc accauucgau uuguuugaga auagaaaaaa aaaaaauaau     1080

aucaaacuau acguaagaag aguauuuaua auggacaauu gcgaagaauu aauaccagaa     1140

uaucuaaauu uuaucagggg aguagucgac agcgaagauu uaccauuaaa cauaucgcga     1200

gagauguuac aacaaucaaa aauucugaaa guaauaagaa aaaaucuagu caaaaaaugu     1260

cuagaacuau ucacagaacu agcagaagac aaagaaaacu acaaaaaauu cuaugaacaa     1320

uucucaaaaa auauaaaauu gggcauacac gaagacucuc agaauagaaa aaaacuauca     1380

gaauuacuaa gauauuauac gucagcuagu ggagacgaga ugguaucccu aaaagacuac     1440

ugcacaagga ugaaagaaaa ucaaaaacau auauacuaca uaacuggaga aaccaaggac     1500

caagucgcaa acucagcauu cguagaaaga uuacgaaagc auggacugga aguaauauac     1560

augauagaac ccauagauga auauugcgua caacaauuaa aagaauucga aggaaaaacu     1620

uuaguaagcg uaacgaaaga aggacuagaa uuacccgaag augaagaaga gaaaaaaaaa     1680

caagaagaga aaaaaaccaa auucgaaaac uuauguaaaa uaaugaaaga cauauuagaa     1740

aaaaaaguag aaaaaguugu aguaucaaac agacuaguaa caagcccaug uugcauagua     1800

acaaguaccu acggguggac ggcaaacaug gaaagaauaa ugaaagccca agcuuuacga     1860

gacaauagua cgaugggaua cauggcagcc aaaaagcauu uagaaauaaa cccagaccac     1920

agcauaaucg aaacacuuag acaaaaagcc gaagcugaua aaaacgacaa auccgugaaa     1980

gaccucguca ucuuacuuua ugaaacagca uuauuaagua guggauucuc ccuagaagac     2040

ccgcaaacac acgcuaaucg aauauaccga augauuaagc ucggauuagg aauagacgaa     2100

gaugacccaa cagcggauga uacaagcgca gcaguaacug aagagaugcc accauuagaa     2160

ggagaugaug auacgucaag gauggaagaa gucgacuaa                            2199


<210>  763
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  763
auggacucaa gcaaacuaga cagcggaaaa ggacuacaca uaaacuuagu accaaacaaa       60

caaaaccaaa cacuaacaau aguagacaca agaauaggaa ugacaaaaac agacuuaaua      120

aacaaccuag gaacaguaac aaaaucagga acaaaagcau ucauggaagc acuacaagca      180

gacgcagaca uaucaaugau aggacacuuc ggaguaggau ucuacucagc auaccuagua      240

gcaaaaaaag uaacaguaau aucaaaacac aacaacgacg aacaauacac augggaauca      300

ucagcaggag gaucauucac aguaagaaca gacgaauaa                             339


<210>  764
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  764
augcccgaag aagugcauca uggcgaagag gagguagaaa cauucgcuuu ucaagcugaa       60

auagcucagc uaaugagccu aauaauaaac acuuuuuaca gcaacaaaga aauauuucuc      120

cgcgaguuaa uaucaaacgc uucagaugca cuugauaaaa uaagauacga gagccuaaca      180

gacccuagua aacuagauag cgguaaagaa cuaaaaauag acauaauacc caacccgcaa      240

gaaagaacac uuacacuugu cgauacugga auaggaauga caaaagcaga ucuaauaaau      300

aacuuaggaa caauagcaaa aucagggacg aaagcguuua uggaagcauu acaagcagga      360

gcagauauua guaugauagg acaauuugga guaggauucu acagugcuua ucuuguagca      420

gaaaaaguag uaguaauaac aaaacacaau gacgacgaac aauaugcuug ggaaucuuca      480

gccggagggu cauucacggu uagagcagac cacggagaac caauaggaag aggcacuaag      540

guaauacuac auuuaaagga agaucagaca gaauaccuug aagaacgaag aguaaaagaa      600

guaguaaaaa aacauucaca auuuauagga uaccccauaa cauuauaccu ggaaaaagaa      660

agagaaaaag aaauaucuga cgacgaagcc gaagaagaaa aaggagaaaa agaagaagaa      720

gacaaagaug augaagaaaa accgaaaauc gaagacguag gaucagacga agaagacgac      780

ucaggaaaag acaaaaaaaa aaaaacaaaa aaaauaaaag aaaaauacau agaucaagaa      840

gaauugaaca aaacaaaacc aauauggaca agaaauccag augauauaac acaagaagaa      900

uauggagaau ucuacaaaag ucuuacaaau gacugggaag accaucuagc agucaaacau      960

uuuucaguag aaggacaacu agaauucaga gcguuauuau uuauaccaag aagagcgcca     1020

uucgaccuau uugaaaacaa aaaaaaaaaa aacaauauaa aacuauacgu aagaagaguc     1080

uucauaaugg acucgugcga ugaauuaaua ccagaauacu uaaauuucau aagaggagua     1140

gucgauuccg aagacuuacc acuaaauaua ucucgagaaa uguuacaaca auccaaaaua     1200

cuaaaaguga uaagaaaaaa uaucguaaaa aaaugucuug aacuauuuuc ggaacuugcg     1260

gaagacaagg aaaauuauaa aaaauuuuau gaagcguuca guaaaaacuu aaagcuaggc     1320

auacaugaag acuccacaaa uagaagaaga cuaagcgaac uauuaagaua ccauacauca     1380

caaucaggag acgaaaugac aucucuaagu gaauauguga gcaggaugaa agaaacccaa     1440

aaaucaauau acuacauaac aggagaaucg aaagaacagg uagcaaauuc agcauucguc     1500

gaacguguac gcaaaagagg auuugaagua guauacauga cugagccaau agacgaauau     1560

uguguacaac aacuaaaaga auucgacgga aaaagucuag ucaguguaac aaaagaagga     1620

cuagaacuac cagaagauga agaagaaaaa aaaaaaaugg aagaaagcaa agcaaaguuc     1680

gaaaauuuau gcaaauuaau gaaagaaaua cuagauaaaa aagucgaaaa aguuacaauu     1740

ucaaauagac uagucucauc accaugcugc auagucacaa gcacauacgg auggaccgcc     1800

aauauggaaa gaauaaugaa ggcacaagca uuaagagaua acagcacgau gggauacaug     1860

auggcaaaaa aacaucuuga aauaaaucca gaccacccaa uagucgaaac acuaagacag     1920

aaagcagaag cagauaaaaa cgacaaagcu guaaaagacc ucgugguccu gcucuucgaa     1980

acagcauuac ugaguucagg auucucgcug gaagacccac agacucauuc aaauagaauu     2040

uacagaauga uaaaacuagg auuaggaauc gaugaagacg aaguggcagc agaagaacca     2100

aacgccgcgg ucccagacga aauaccucca uuagaaggag acgaggaugc aagccgaaug     2160

gaagaaguag auuaa                                                      2175


<210>  765
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  765
augcgagcuu uauggguacu aggcuuaugu ugcguauuac uuacauucgg aucaguacgu       60

gcagacgaug aaguagaugu agaugguaca guagaagaag auuuaggcaa aucaagagaa      120

ggaaguagga cagacgauga gguaguacaa agagaagaag aagcaauuca acuagacgga      180

cuuaacgcau cucaaauaag agaauuacga gaaaaaucag aaaaauuugc auuccaggca      240

gaaguaaaua gaaugaugaa acuaaucaua aauagucucu auaaaaacaa agaaauauuc      300

uuacgagaac uaauaucaaa ugcaagugau gcuuuagaca aaauacgacu uaucagucua      360

acagaugaaa augcacucag uggcaaugaa gaacuaacag uuaaaauaaa augcgauaaa      420

gagaaaaauu uacuacaugu uacagacacc gguguaggaa ugacaagaga agaauuaguu      480

aaaaauuuag gaacaauagc aaaaagugga acaagugaau uucuaaauaa aaugacugaa      540

gcucaggaag auggacaaag cacuucagaa cuaauuggac aauucggagu aggauucuac      600

ucagcauucc uuguagcuga uaaaguaauc guaacuagca aacacaauaa cgacacacaa      660

cauauauggg aaucagauuc aaacgaauuu agcguaauug cagauccaag aggaaauaca      720

cuaggaagag ggaccacaau aacauuagua cuaaaagagg aagcaagcga cuacuuagaa      780

cucgauacga uuaaaaauuu aguaaagaaa uacucacagu uuauaaauuu cccaauauac      840

gucuggagua guaaaacaga aacaguagaa gaaccaaugg aggaagaaga agcagccaaa      900

gaagaaaaag aagaaucgga cgacgaagcu gcugucgaag aagaagaaga agaaaagaaa      960

ccaaaaacaa agaaaguaga gaaaacuguu ugggauuggg aauuaaugaa cgauaucaaa     1020

ccaauauggc aaagacccuc aaaagaaguc gaagaagacg aauauaaagc cuuuuacaag     1080

ucauuuucca aagaaucgga ugacccaaug gcauauauuc acuuuacagc agagggagaa     1140

gucacauuua aaucuauacu uuuuguccca acaagugcac cgagaggauu auuugaugaa     1200

uacgguucaa agaaaucaga cuauauaaaa uuauauguaa gaagaguguu cauaacagac     1260

gacuuucacg auaugaugcc gaaauacuua aacuuuguua aaggagucgu ugacagcgau     1320

gaccuaccac ucaacguaag uagagaaaca cuacaacaac auaaacuauu gaaaguuaua     1380

agaaagaaac ucguaagaaa aacuuuagac augauuaaga aaauagcaga cgacaaauau     1440

aacgauacau uuuggaaaga guucgguaca aauauaaaac uaggaguaau agaagaccac     1500

aguaauagaa cccgauuagc caaauuacuc agguuccaau caucgcauca cccaacagac     1560

aucacgagcu uagaucaaua uguagaaaga augaaagaaa aacaagauaa aauauacuuu     1620

auggcgggau caucaagaaa agaagccgaa ucuucuccau ucguugaacg acuauuaaag     1680

aaaggauaug aaguaauaua ccuaacagaa ccuguagaug aauauuguau acaagcacua     1740

ccagaauuug auggcaaacg cuuccaaaau guagcaaaag aaggcguuaa auuugaugaa     1800

agcgaaaaga caaaagaaag uagagaagcg guugaaaaag aguucgaacc auuauuaaau     1860

uggaugaaag acaaagcacu aaaagauaaa auagaaaaag cuguaguauc ucaaagauua     1920

accgaauccc cgugcgcacu cguagccagu caauauggcu ggucagguaa cauggaaaga     1980

auaaugaaag cucaagcaua ucaaacagga aaagauauaa guacgaacua uuacgcaucu     2040

caaaagaaaa cauucgaaau aaauccaaga cacccacuga uaagagauau guuaaggcga     2100

auaaaagaag augaagacga caaaacaguu cuagacuuag cugucguacu auucgaaaca     2160

gcaacauuaa gaagcggaua cuuacuacca gacacaaaag cauauggaga uaggauagaa     2220

cggauguuac gacuaagucu caacauagau ccagaugcca aaguugaaga agaaccagaa     2280

gaggaaccag aagagaccgc agaagacaca acagaagaca cagaacagga cgaagacgaa     2340

gaaauggacg uaggaacuga cgaagaagaa gaaacagcaa aagaaucuac agcagaaaaa     2400

gacgagcugu aa                                                         2412


<210>  766
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  766
auggcacgag aauuaagagc ucuuuuacua ugggguagac gacugagacc auuauuaagg       60

gcgccagccc ucgcagcagu accaggagga aaaccaauac ucugcccaag aagaacaacc      120

gcacaauuag gcccaagaag aaauccagca uggucauuac aagcuggaag acuauuuucc      180

acccaaacag cagaagauaa agaagaaccc uuacauucaa uaauaucaag cacagaauca      240

guccaaggau caacaucaaa acaugaauuu caagcagaaa caaagaaacu auuagauauu      300

guugcuagaa gccuuuauuc ugaaaaagaa guauuuauaa gagaacuaau uaguaacgcu      360

agcgacgccu uagaaaagcu aagacacaag uuaguaagug auggacaagc auuaccagaa      420

auggaaauac accugcaaac caaugcagaa aaaggaacaa uaaccauaca agauaccggc      480

auaggaauga cacaagaaga auuaguaagu aaccuuggaa caauagcuag aagcggauca      540

aaagcauucc ucgacgcacu acaaaaccaa gcagaagcau cauccaaaau aauuggacaa      600

uuuggcguag gauucuauag ugccuuuaug guagcagauc gugucgaagu cuauucacga      660

ucagcagcac caggaucacu aggguaucaa ugguuaucag acggauccgg uguauucgaa      720

auugccgaag ccucgggcgu aagaacgggu acuaaaauaa uaauacauuu aaaaucagau      780

ugcaaagaau ucucuucaga agcacgaguc cgagauguag uaacgaaaua uucaaacuuu      840

guuaguuuuc ccuuauauuu aaauggucgu agaaugaaua ccuuacaagc aauauggaug      900

auggauccaa aagauguuag agaauggcaa caugaagaau uuuauagaua uguugcucaa      960

gcucaugaca aaccccgaua uacuuuacac uacaaaacag acgcaccauu aaauaucagg     1020

aguauauuuu augugccaga uaugaaaccc ucgauguuug augucaguag agaauuagga     1080

agcagugugg cucuauauuc uagaaaagua cucauacaaa ccaaagcaac ggauauauua     1140

ccaaaauggc ucagauuuau aagaggaguu guugauucag aagacauacc cuuaaaucuu     1200

aguagagaac uacuucaaga aucagcauua auaagaaaau uaagagacgu ccuucaacaa     1260

agauuaauua aauucuuuau agaccaauca aaaaaagaug cagaaaaaua ugcaaaauuc     1320

uucgaagacu auggauuauu uaugagagaa ggaauaguaa cagcaacaga acaagaagua     1380

aaagaggaua uagcaaaauu auuacgguac gaaucaucag cauuaccauc aggacaacuu     1440

acaucauuau ccgaauacgc cagucgaaug agagcaggca caagaaacau auauuaccua     1500

ugugcaccaa acagacaucu agcagagcac ucaccuuauu acgaagcaau gaaaaaaaaa     1560

gauacagaag uucuauuuug cuuugaacaa uuugacgagc uuaccuuacu ccaucuaaga     1620

gaauuugaca aaaaaaaauu aauaaguguu gaaacagaca uaguaguuga ucauuauaaa     1680

gaagaaaaau uugaagaucg aagcccagca gcagaaugcc uaucagaaaa agaaaccgaa     1740

gaauuaaugg ccuggaugcg uaauguucua ggaagcagag uuacaaacgu aaaaguaacg     1800

cuaagauuag auacucaucc agccauggua acugugcuag aaaugggcgc agccaggcac     1860

uuccuaagaa ugcaacaauu agcaaaaaca caagaagaaa gagcacaauu acuucaacca     1920

acacuugaga uaaaucccag acaugcauua aucaaaaaac uaaaccaacu ucgugcaagc     1980

gaaccaggau uagcacaacu uuuaguugau caaauauaug aaaacgcaau gauagcagcu     2040

ggacucgucg augauccaag agcaauggug ggacgccuua augaauuauu gguaaaagca     2100

uuggaacgac auuaa                                                      2115


<210>  767
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  767
augggaaaaa uaucaucacu accaacacaa cuauucaaau gcugcuucug cgacuuccua       60

aaaguaaaaa ugcacacaau gucaucauca caccuauucu accuagcacu augccuacua      120

acauucacau caucagcaac agcaggacca gaaacacuau gcggcgcaga acuaguagac      180

gcauuacaau ucguaugcgg agacagagga uucuacuuca acaaaccaac aggauacgga      240

ucaucaucaa gaagagcacc acaaacaggc auaguagacg aaugcugcuu ccgaucaugc      300

gaccuaagaa gacuagaaau guacugcgca ccacuaaaac cagcaaaauc agcaagauca      360

guaagagcac aaagacacac agacaugccc aaaacacaaa aagaaguaca ccuaaaaaac      420

gcauccagag gaucagcagg aaacaaaaac uacagaaugu aa                         462


<210>  768
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  768
augggaauac caaugggaaa aucaaugcua guacuauuaa cauuucuagc auuugcaagc       60

uguugcauug cagcauacag accaucagaa acacuaugug gaggagaauu aguagauaca      120

uuacaauuug uauguggaga uagaggauuc uauuucucaa gaccagcauc aagaguuagc      180

agaagaagua gaggaauagu agaagaaugc uguuucagaa gcugugauuu agcauuacua      240

gaaacauauu gcgcaacacc agcaaaaagu gaaagagaug uaucaacacc accaacugua      300

uuaccagaua acuuuccaag auacccagua ggaaaauucu uucaauacga uacauggaaa      360

caaagcacac aaagacuaag aagaggacua ccagcauuau uaagagcaag aagaggacac      420

guucuagcaa aagaacuaga agcauuuaga gaagcaaaaa gacauagacc acuaauagca      480

uuaccaacac aagauccagc acacggagga gcaccaccag aaauggcauc aaacagaaaa      540

uaa                                                                    543


<210>  769
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  769
augaauuccu ucucaacauc agccuucgga ccaguagccu ucucacuagg acuacuacua       60

guacuacccg cagcauuccc agcaccaguc ccaccaggag aagacucaaa agacguagca      120

gcaccacaca gacaaccauu aacaucauca gaacgaauag acaaacaaau aagauacaua      180

uuagacggaa uaucagcacu aagaaaagaa acaugcaaca aaucaaacau gugcgaauca      240

ucaaaagaag cccuagcaga aaacaaccuu aaucuaccaa aaauggcaga aaaagacgga      300

ugcuuccaau caggauucaa cgaagaaaca ugccuaguaa aaauaauaac aggacuacua      360

gaauucgaag uauaccucga auaccuacaa aacagauucg aauccucaga agaacaagcc      420

cgagcagucc aaaugucaac aaaaguacua auacaauucu uacaaaaaaa agcaaaaaau      480

cuagacgcaa uaacaacacc agacccaaca acaaacgccu ccuuacuaac aaaacuacaa      540

gcacaaaacc aaugguuaca agacaugaca acacaccuca uacuaagauc auucaaagaa      600

uuccuacaau ccucacuaag agcacuuaga caaauguaa                             639


<210>  770
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  770
augccacuac ugugguuaag agguuuccua uuagcaagcu gcuggauaau aguaagaagc       60

aguccaacac cagggagcga aggacacagu gcggcaccag acugcccauc augugcgcua      120

gcagcauuac caaaagacgu uccaaauagu caaccagaaa ugguugaagc aguaaaaaaa      180

cauauauuaa auaugcuaca ucuaaaaaaa agaccagaug uaacacaacc aguaccgaaa      240

gcagcauuau uaaaugcaau acgaaaauua caugucggaa aaguaggaga aaacggauau      300

guagaaauag aagacgacau uggaagaaga gcagaaauga acgaauuaau ggaacaaaca      360

agugaaauua uaacguuugc agaaucagga acagccagaa aaacacuaca cuuugaaaua      420

ucaaaagaag gcucagaccu aucaguugua gaaagagcgg aaguaugguu auuucuaaaa      480

guaccuaaag caaacagaac aagaacaaaa guaacaauua gacuauuuca acaacaaaaa      540

cacccacaag gaagucuaga uacaggagaa gaagcagaag aaguaggauu aaaaggagaa      600

aggagugaau uacuauuaag ugaaaaagua guagacgcaa gaaaaucaac auggcacgua      660

uuuccaguau caucaagcau acaacgacua cuagaccaag gaaaauccuc auuagaugua      720

agaaucgcau gcgaacaaug ucaagaaagu ggugcaucau uaguacuauu aggaaaaaaa      780

aaaaaaaaag aagaagaagg agaaggaaaa aaaaaaggag gaggagaagg aggugcagga      840

gcagacgaag aaaaagaaca aagccauaga ccauucuuaa uguuacaagc aagacaaagu      900

gaagaccauc cucauaggag aagaagaaga ggacuugaau gcgacggaaa aguaaauaua      960

uguuguaaaa aacaauucuu uguaagcuuu aaagauauag gauggaacga uuggauaaua     1020

gcuccaagug gauaucacgc aaauuacugc gaaggagaau gcccaucaca cauagcggga     1080

acaagcggaa gcucacuauc auuccauagc acaguaauaa accauuacag aaugagagga     1140

cauaguccau ucgcaaacuu aaaaucaugc ugugucccaa caaaacuaag accaaugucc     1200

auguuauauu augaugacgg ucaaaauaua auaaaaaaag auauacaaaa caugauagua     1260

gaagaaugug gcuguagcua a                                               1281


<210>  771
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  771
auggauggau uacccgggag ggcacuaggu gcagcuugcc uauuacuacu agcagcagga       60

uggcuaggac cagaagcaug gggaagcccg acaccaccuc cuacaccagc agcaccacca      120

ccaccuccuc caccaggauc accaggagga agucaagaca cauguacauc augcggagga      180

uuccgaagac cagaagaacu aggaagagua gauggagauu uucuagaagc aguuaaacga      240

cauauacuau cuagacuaca aaugcgagga agaccaaaua uaacacacgc aguuccaaaa      300

gcagcaaugg uaacagcacu uagaaaauua caugcaggua aaguacguga agauggaaga      360

guagaaauac cacaucuaga cggucacgcu ucaccaggag cugacgguca agaaagagua      420

ucagaaauca ucagcuuugc cgaaacugau ggacuagcau caucacgagu uagauuauau      480

uuuuuuauua guaaugaagg aaaucaaaau uuauucguug uccaagcuuc auuauggcuu      540

uauuuaaaau uacuaccuua uguauuagaa aaaggaucaa gaagaaaagu aagaguuaaa      600

gucuauuucc aagaacaagg ucauggagau agauggaaua ugguagaaaa aagaguagac      660

cuaaaaagau caggauggca cacuuuccca uuaacagaag caauacaagc auuauucgaa      720

agaggagaaa gaagacuaaa uuuagacguu caaugugacu caugucaaga auuagcagua      780

guaccaguuu uugucgaucc aggagaagaa agucauagac cuuuuguagu aguacaagcg      840

agauuaggag auucaagaca cagaauaagg aaaagaggau uagaauguga cgggagaaca      900

aacuuauguu guagacaaca auuuuuuaua gauuuucgac uaauaggaug gaaugauugg      960

auaauagcac cuacaggaua uuauggaaau uauugugaag gaaguugucc agcauauuua     1020

gcaggaguac caggaucagc aagcaguuuu cauacagcag uaguuaauca auauagaaug     1080

agaggacuaa auccuggaac gguaaauucg uguugcauuc cuacaaaacu aucaacaaug     1140

agcauguuau acuucgauga cgaauauaau auaguuaaaa gagacguacc aaacaugauu     1200

guagaagaau guggaugugc uuga                                            1224


<210>  772
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  772
auggcucuca gaguacuacu acuaacugca cuaacuuuau gccacggcuu caacuuagau       60

accgaaaacg ccaugacuuu ucaagaaaau gcaagagguu ucggacaauc uguaguacaa      120

cuacaaggcu caaggguagu uguaggcgcc ccucaagaaa ucguagccgc uaaucagcga      180

gguucucuuu aucaauguga uuauucaacu ggauccugug aacccauccg auuacaagua      240

ccuguagaag cuguaaauau gucacuugga cuaagucucg cugcaacaac aucacccccg      300

caacuacucg cauguggccc aaccguacau cagacauguu cugaaaacac auacguaaaa      360

ggauuauguu uccuauuugg caguaacuua cgacaacaac cacaaaaauu cccagaagcc      420

uuaagaggau guccucaaga agauagcgau auugcauucc ucauagaugg aucugguucc      480

auuauaccuc augauuuccg gcgaaugaaa gaauuuguuu caacagucau ggaacaacua      540

aagaaaucaa aaacauuauu uuccuuaaug caauauagug aagaguuccg aauacauuuu      600

accuucaaag aauuucaaaa uaacccaaac ccgcgaaguc ucguaaaacc cauuacccaa      660

cuucuaggua gaacucacac agcaacaggu auuagaaaag uuguucgaga guuauuuaau      720

auuacaaacg gagcacguaa aaacgcuuuc aaaauccuag uuguaauaac agacggagaa      780

aaauuuggug acccacuagg uuaugaagau guuaucccag aggcugacag agaaggaguc      840

auuagauaug ucauaggagu aggagaugca uuccgcagug agaaaaguag acaggaacuu      900

aacacgauag ccucuaaacc cccaagggau cacgucuucc aaguaaacaa cuuugaggcu      960

uuaaaaacca uacaaaacca auugcgugag aaaauuuuug cuauagaagg gacacaaacu     1020

ggauccucau cuucauuuga acaugaaaug ucucaagaag gauuuucagc agccaucaca     1080

ucaaacggac cuuuacuauc aaccguuggc uccuaugauu gggcuggagg agucuuccuu     1140

uauacuucua aagaaaaauc cacuuuuaua aauaugaccc ggguugauag cgacaugaau     1200

gacgccuauu uggguuaugc agcugcuaua auacuacgaa aucgugucca aaguuuaguc     1260

cuaggagcuc ccagauauca gcauauuggu uuaguugcga uguuuagaca aaacacaggu     1320

augugggaau caaaugcaaa uguuaaagga acacaaauug gggcauauuu cggcgcuucc     1380

cuauguucag uagacgucga uucaaaugga uccacggauu uaguucucau aggugcacca     1440

cacuauuaug aacaaacccg agguggccaa gucuccguau gcccccuacc acgcggccgu     1500

gcacguuggc agugcgacgc uguacuuuau ggugaacaag gacaaccuug gggacguuuu     1560

ggagcagccc uaacuguacu uggagacguu aauggcgaca aauuaacgga uguugcgauc     1620

ggggcaccag gcgaagaaga uaauagagga gccguauacu uauuucaugg cacaagcggc     1680

ucaggaauau caccuucaca uagucaaaga auagcaggau caaaacuauc uccaagauua     1740

caauacuuug ggcaaagucu aagcggcgga caagaccuua caauggaugg auuaguagau     1800

cuaaccguug gagcacaagg acauguauua uuauuaagau cccaaccugu ucuuagaguc     1860

aaagcuauua uggaauuuaa cccuagagaa guagcucgca auguuuuuga auguaaugau     1920

cagguuguua aagguaaaga agcaggagaa guccguguuu gucuucacgu acagaaauca     1980

acuagggaua gacuaagaga aggacaaaua caaaguguug uuacauauga uuuagcacua     2040

gacucugguc gaccacauuc aagagcaguu uucaacgaga cuaaaaacuc aacacgaaga     2100

caaacccagg uauuagguuu aacacaaacu ugcgaaacac uuaaacuaca auuaccuaau     2160

ugcauagaag auccaguuuc accaauaguc cuacgauuaa acuucucauu aguuggcacc     2220

ccacuguccg cuuucggaaa ccuacguccc guccucgcag aagacgcaca aagacuauuu     2280

acagcuuuau ucccuuuuga aaagaauugc ggcaaugaua auauauguca agacgaucuu     2340

ucaauuacuu uuaguuuuau gucacuagau ugccuaguag uaggaggacc aagagaauuu     2400

aauguaacag uuacaguacg caacgacgga gaagacucuu aucgaacaca aguuacauuu     2460

uucuuuccau uagacuuaag uuaccgaaaa guaucaaccc uucaaaauca acgaucacaa     2520

agaucaugga gguuagccug cgaaucggca ucauccacug aaguaucugg ugcacucaaa     2580

aguacuucau guuccauuaa ucauccuaua uuuccugaaa auuccgaagu aaccuuuaac     2640

auaacauuug auguugauuc aaaagccucu cucgguaaua aauuacuacu uaaagcaaac     2700

gugacauccg aaaauaacau gccaagaacu aauaaaacgg aauuucaauu agaauuaccu     2760

guuaaguacg cagucuacau gguugugaca agucauggcg uuuccacaaa auaucuuaac     2820

uuuacagcaa gugaaaacac aucaaggguu augcaacauc aauaucaagu caguaaccuu     2880

ggucaacgaa gccuaccaau cucauugguc uuucucgucc caguaagacu aaaucaaacc     2940

guaauauggg aucgaccgca aguuacuuuc agugaaaacu uaaguucuac augccacaca     3000

aaagaaagac uuccaucuca cucugacuuu cuagcugaac uacgaaaagc ucccguugua     3060

aacuguucua uagcaguuug ucaacguaua caaugugaua uuccauucuu uggaauacaa     3120

gaagaguuca augcuacauu aaaagguaau uuaucguuug auugguacau uaaaacuagc     3180

cauaaucauu uauuaauagu uucuacugca gaaauccugu uuaaugauuc cguauucacu     3240

cuauuacccg gacaaggagc auuuguaaga ucccaaaccg aaacaaaagu agaaccuuuu     3300

gaagucccca acccucuucc uuuaaucguu ggaucaagcg uuggcggacu auuacuuuua     3360

gccuuaauaa cggcggcauu auauaaauua ggauucuuca aacgccaaua uaaagauaug     3420

augucugaag guggaccucc uggagcagaa ccacaauaa                            3459


<210>  773
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  773
auguuuucac uaaaaacauu accuuuccua cuucuacuac acguacaaau aucaaaagca       60

uuuccagucu caucaaaaga aaaaaacaca aaaacaguac aagauuaucu cgaaaaauuu      120

uaccaauuac caucaaauca auaucaauca acacgaaaaa auggaacaaa cguaauaguu      180

gaaaaauuaa aagaaaugca aagauucuuu ggacucaaug ucacaggcaa accuaacgaa      240

gaaacacuag acaugaugaa aaaaccaaga ugcggaguac cagacucagg aggauucaug      300

uuaaccccag gcaacccuaa augggaaaga acaaaucuaa cauacagaau acgaaacuau      360

acaccacaac uauccgaagc agaagucgaa agagcaauaa aagacgcuuu ugaacuuugg      420

ucaguagccu ccccacuaau auucacacga auaucacaag gagaagccga caucaacaua      480

gcauuuuauc aacgagacca cggagacaau ucccccuucg acggaccaaa uggaauacua      540

gcacacgcau uccaaccugg acaaggaaua ggaggagaug cacauuucga cgcagaagaa      600

acauggacaa acacaucagc aaacuacaac cuauucuuag ucgcagcaca cgaauucgga      660

cauucucuag gacuagccca uucaucugac cccggcgcac uaauguaucc aaacuacgca      720

uuuagagaaa cauccaacua cucccuaccc caagacgaua uagaugguau ccaagcaaua      780

uacggacuau ccucaaaucc aauacaacca acaggccccu cuacaccaaa accaugcgac      840

ccaucccuua cauucgacgc aauaacaacc cuccgaggag aaauauuauu cuuuaaagac      900

agauacuucu ggagaagaca cccucaacuc caacgaguug aaaugaacuu cauaucuuua      960

uuuuggccau cucuaccaac agggauccaa gcagcuuacg aagauuuuga ucgcgacuua     1020

auauuuuuau ucaaaggaaa ucaauacugg gcauuaucag gauaugauau acuacaagga     1080

uaccccaaag acauaucaaa uuauggauuc cccuccucag uccaagccau cgacgcugca     1140

guauucuacc gaucaaaaac cuacuucuuu guaaaugacc aauuuuggag auacgauaau     1200

caacgucaau ucauggaacc ugguuaucca aaaucaauau cuggcgcauu ucccggaaua     1260

gaaagcaaag uagacgcagu cuuucaacaa gaacacuucu uccacguauu uagcggacca     1320

agauacuacg ccuuugacuu aauagcacaa agaguaacac gaguugcaag aggaaacaaa     1380

uggcuaaacu guagauacgg auaa                                            1404


<210>  774
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  774
augagucuau ggcaaccauu aguauuaguu uuacuuguac ucgguuguug cuucgcugca       60

ccuagacaac gucaaucaac ccucgugcuc uuuccaggag aucuucgaac uaauuuaaca      120

gauagacaau uagcagaaga auauuuauau agguauggcu auacacgagu agcugaaaug      180

cgaggagaaa guaaaagccu aggaccugcc uuauuacuac uacaaaaaca acuaucauua      240

ccagaaacug gagaauuaga cuccgcuacu cuaaaagcaa ugcgcacccc acguugcgga      300

guaccagauu uaggacgauu ucaaacauuu gaaggagauu uaaaauggca ucaucacaau      360

auaacauacu ggauucaaaa cuacagugaa gauuuaccca gggcaguaau agacgaugca      420

uuugcaaggg cauuugcauu auggucagcu guuacuccac ucacuuucac uagaguuuac      480

aguagagaug cagauaucgu aauacaauuu ggaguagcag aacacggcga cggauaccca      540

uucgacggua aagauggacu acuagcucau gccuucccac cagguccagg uauacaagga      600

gacgcacauu uugaugauga ugaauuaugg aguuuaggca agggaguugu cguaccaacu      660

cgauuuggaa augcugaugg ugcagcuugc cauuuucccu uuauuuucga agggagaucg      720

uauucagcuu gcacaacaga cggaagaucc gauggucuac cauggugcuc uacaacagcu      780

aacuaugaca cagacgauag auucggauuc ugcccauccg aacgauuaua uacucaagau      840

ggaaaugcag acgguaaacc augucaauuc ccauuuauau uccaaggaca aucauauagc      900

gcuugcacaa cagauggaag aagcgaugga uacagauggu gcgcaacaac agcuaacuau      960

gaucgagaca aacuauuugg auuuugucca acacgugcug auuccacagu aaugggagga     1020

aauucugcug gugaacuaug uguauuccca uuuacauucc uugguaaaga auacucuaca     1080

uguacaagcg aaggcagagg cgacggaaga cuuuggugug cuacaacauc uaauuuugau     1140

agugauaaaa aauggggauu cuguccagac caaggauacu cauuauuucu aguagcugca     1200

caugaauuug gacaugccuu aggauuagau cauaguucug uaccagaagc ucugauguau     1260

ccuauguacc gauucacuga aggaccacca cuccauaaag acgauguuaa uggaauaaga     1320

cauuuguacg gacccaggcc agaaccagaa ccaagaccac caacaacaac aacuccucaa     1380

ccgacagcac caccaacagu uuguccaaca ggacccccca caguacaucc aucagaaaga     1440

ccuacagcag gaccaacagg uccgccauca gccggaccaa cuggaccucc aacagcaggc     1500

cccuccacag caacaacagu accauuauca ccaguagaug augcaugcaa uguaaauaua     1560

uuugaugcua uagcagagau aggcaaucaa cuauaucucu uuaaagacgg aaaauauugg     1620

agauucucag agggcagagg aucaagaccc caaggaccau uuuuaauugc agauaaaugg     1680

ccagcuuuac caaggaaauu agauucaguc uuugaagagc gccucucaaa aaaauuauuu     1740

uuuuucucag gaagacaagu cuggguuuau accggagcau ccguauuagg accaagaaga     1800

uuagacaaau uagguuuagg ugcugauguc gcacaaguua caggagcuuu acgaagcggu     1860

cgaggaaaaa ugcuacuguu cucugguaga agacuaugga gauuugacgu aaaagcgcaa     1920

augguagacc cucgaagcgc uagugaagua gauagaaugu ucccuggugu accucuugac     1980

acccaugacg uuuuucaaua cagagaaaaa gcauauuuuu gccaagaucg cuucuacugg     2040

cgaguuaguu cacguagcga acuaaaucaa guagaccaag uuggauaugu cacauacgau     2100

auacuacaau guccagaaga cuaa                                            2124


<210>  775
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  775
augcacccag guguacuugc agccuucuua uuuuuaucau ggacucacug uagagcacuc       60

ccacuaccau caggaggaga cgaagaugau uuaucagaag aagaccucca auucgcagaa      120

agauaucuaa gaucuuacua ucacccaaca aacuuagcag guauacuaaa agaaaacgca      180

gcaucaucaa ugacagaaag acuaagagaa augcaaucau ucuuuggauu agaaguaaca      240

ggaaaacuag augauaauac acuagacgua augaaaaaac ccagaugcgg aguaccugau      300

guaggagaau acaacguauu cccaagaaca cuaaaauggu caaaaaugaa ucuaacauac      360

agaaucguaa acuauacccc agacaugaca cauagugaag uagaaaaagc auucaaaaaa      420

gcauucaaag uauggucaga cguaacacca uuaaacuuca ccagacuuca cgauggaaua      480

gcagacauua ugauuucauu uggcauaaaa gaacauggcg acuucuaccc auucgacggu      540

ccaagcgguu uacuagccca ugcauuccca ccuggaccua acuauggcgg agacgcacac      600

uuugacgaug acgaaacaug gaccaguuca aguaaaggau acaaucuauu uuugguagcu      660

gcccacgaau ucggccacuc acuaggacua gaccauucaa aagacccugg ugcauuaaug      720

uucccaauau auaccuauac aggaaaauca cauuucaugu uaccagauga ugauguacaa      780

ggcauccaau cauuauacgg cccaggagac gaagauccaa acccaaaaca cccaaaaaca      840

ccagacaaau gcgacccuuc acuaucucua gacgcaauaa cuucuuuaag aggagaaaca      900

augauauuca aagaucgauu cuucuggaga cuucacccac aacaaguaga ugcagaacua      960

uucuuaacaa aaucuuucug gccagaacua ccaaaccgua ucgacgcagc auaugaacac     1020

ccaucacaug acuuaauauu uauauuuaga ggacgaaaau uuugggcauu aaacggauau     1080

gauauauuag aaggauaccc uaaaaaaaua ucagaacucg gauuaccaaa agaaguuaaa     1140

aaaauaucgg cagcuguaca cuucgaagac acaggcaaaa cccuauuauu uucaggaaac     1200

caaguauggc gauaugacga cacaaaucau auaauggaua aagauuaccc aagauuaaua     1260

gaagaagauu ucccaggaau aggugacaaa guagacgcag uauacgaaaa aaaugguuac     1320

auauauuuuu uuaacggacc cauacaauuc gaauacucaa uauggucaaa cagaauagua     1380

cgagucaugc cagcaaauuc gauacuuugg ugcuaa                               1416


<210>  776
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  776
auggaaacac caaacacaac agaagacuac gauacaacaa cugaauucga cuacggagac       60

gcaacaccau gucaaaaagu caacgaacga gcauucggag cacaauuacu accuccacua      120

uacucauuag uauuuguaau aggcuuaguc ggaaacauac uaguaguacu aguuuuaguu      180

caauacaaaa gacuaaaaaa caugacaucu auauacuuac uaaacuuagc aauaucagau      240

cuucuauucu uauucacccu uccauucugg auagacuaca aauuaaaaga cgacugggua      300

uucggcgacg caaugugcaa aauauuaucc ggauucuauu acacaggacu auacucagaa      360

auauuuuuca uaauacuccu aacaauagac agauaccuag caauaguuca cgcaguauuc      420

gcuuuaagag caagaaccgu aacauucgga guuauaacau caauuauaau cugggcacua      480

gccauacuag ccucaaugcc aggacuauac uucucuaaaa cucaauggga auucacacac      540

cauacauguu cacuccacuu uccccaugaa uccuuaagag aauggaaacu cuuccaagca      600

cuaaaauuaa acuuauucgg acuaguauua ccacuacuag uaaugauaau augcuacaca      660

ggaauuauaa aaauccuacu uagaagacca aacgaaaaaa aaucaaaagc agucagacua      720

auauucguca uaaugauaau cuuuuuuuua uucuggacac cuuacaaucu cacuaucuua      780

auaucaguuu uccaagacuu ccuauucaca cacgaaugug aacaaucaag acacuuagac      840

uuagcaguac aagucacuga aguaauagca uacacacacu gcugcguaaa cccaguaauc      900

uacgcauucg uaggagaaag auuuagaaaa uaccuaagac aacuauucca cagaagaguu      960

gcuguacacc uaguaaaaug guuacccuuc uuaucagucg aucguuuaga aagagucuca     1020

ucaacaucac ccucaacagg ugaacacgaa cuaucagccg gauuuuaa                  1068


<210>  777
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  777
augagaacau uagcaugcuu auuacuauua ggauguggau acuuagcaca cguauuagcg       60

gaagaagcag aaauaccaag agaaguaaua gaaagacuag cacgaucaca aauacacuca      120

auaagggacc uacaaagauu acuagaaaua gacucaguag gaagcgaaga cucacuagac      180

acaucauuaa gagcacacgg aguacacgca acaaaacacg uaccagaaaa aagaccacua      240

ccaauaagaa gaaaaagaag cauagaagaa gcaguaccag caguaugcaa aacaagaaca      300

guaauauaug aaauaccacg aucacaagua gacccaacau cagcaaacuu cuuaauaugg      360

ccaccaugcg uagaagugaa aagaugcaca ggcugcugca acacaucguc aguaaaaugc      420

caaccaagca gaguacacca cagaucagua aaaguagcua aaguagaaua cguaagaaaa      480

aaaccaaaac uaaaagaagu acaaguaaga cuagaagaac accuagaaug cgcaugcgca      540

acaacaagcc uaaacccaga cuaccgagaa gaagauacag gaagaccgcg agaaagugga      600

aaaaaacgaa aaagaaaaag acuaaaacca accuaa                                636


<210>  778
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  778
augaauagau gcugggcacu auucuuaagc uuauguugcu acuuaagacu aguaucagca       60

gaaggagauc caauaccaga agaauuauac gaaaugcuaa gcgaccacuc aaucagaagc      120

uuugacgauu uacaaagacu acuacaugga gauccaggag aagaagacgg agcagaacua      180

gacuuaaaua ugacaagauc acacucagga ggagaauuag aaucacuagc aagaggaaga      240

agaagucuag gaucacuaac aauagcggaa ccagcaauga uagcagaaug uaaaacacga      300

acagaaguau ucgaaauauc aagaagauua auagacagaa caaaugcaaa cuuccuagua      360

uggccaccau gcguagaagu acaaagaugc ucaggauguu gcaauaacag aaacguacaa      420

uguaggccaa cacaaguaca auuaagacca gugcaaguaa gaaaaauaga aauaguacgu      480

aaaaaaccaa uauuuaaaaa agcaacagua acacuagaag accaucuagc auguaaaugc      540

gaaacaguag cagcggccag accaguaaca agaagcccag gaggaaguca agaacaaaga      600

gcaaaaacac cacaaacuag aguuacaaua agaacaguaa gaguaagaag accaccaaaa      660

ggaaaacaua gaaaauucaa acacacacau gauaaaacag cacuaaaaga aaccuuagga      720

gcauga                                                                 726


<210>  779
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  779
augagcuuau ucggacuacu acuccuuacu ucagcacuag caggacaaag acaaggaaca       60

caagcagaau caaaccuaag cucaaaauuc caauuuucau caaacaaaga acaaaaugga      120

guacaagauc cacaacacga aaggauuauu acagucucaa caaacggaag uauacacagu      180

ccaagauucc cacauacaua cccaagaaac acaguuuuag ucuggcgacu aguagcagua      240

gaagaaaaug uauggauaca acuaacauuc gaugaaagau ucggauuaga agacccagaa      300

gacgacauau gcaaauauga cuuuguagaa gucgaagaac caagugacgg uacaauacua      360

ggaagauggu gcggaucagg aacaguacca ggcaaacaaa uaaguaaagg aaaccaaauu      420

agaauaagau ucguaucaga ugaauacuuu ccaucagaac caggauucug cauacauuac      480

aacauaguaa ugccacaauu caccgaagca guuucaccau caguuuuacc accaagugcc      540

cucccauuag accuacuaaa caacgcaaua acugcauuca guacucuaga agaccuaaua      600

agauaccuag aaccagaaag auggcaauua gaucucgaag accuauauag accaacaugg      660

caacuauuag gcaaagcauu uguauucgga agaaaaucaa gaguaguaga cuuaaaccua      720

uuaacagaag aaguaagacu auacagcugc acaccaagaa acuuuucagu uucaauaaga      780

gaagaauuaa aaagaacaga uacaaucuuc uggccaggau gucuauuagu caaaagaugc      840

ggcggaaacu gcgcaugcug ccuacauaac ugcaacgaau gccaaugcgu accaaguaaa      900

guaacaaaaa aauaccacga aguauuacaa cuaagaccaa aaacuggagu aagaggucua      960

cacaaaucac uaacugacgu agcauuagaa caucacgaag aaugugacug cgucugcaga     1020

ggaucaacag gaggauaa                                                   1038


<210>  780
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  780
augcacagac uaauauucgu auacacacuc auaugcgcaa auuucugcuc auguagagac       60

acaucagcaa caccacaauc agcaucaaua aaagcacuaa gaaacgccaa ccuaagacga      120

gacgauuuau acagaagaga cgaaacaaua caaguaaaag guaacggaua uguacaauca      180

ccaagauucc caaacaguua cccaagaaau cuacuacuaa cauggagacu acacucacaa      240

gaaaacacaa gaauacaacu aguauuugac aaccaauuug gacuagaaga agcugaaaac      300

gacauaugua gauaugacuu cguagaagua gaagacauaa gugaaacauc aacaauaauu      360

agaggaagau ggugcggcca caaagaagua ccaccccgaa uaaaaucaag gacaaaccaa      420

aucaaaauaa cuuucaaauc agacgacuac uuuguagcaa aaccaggcuu uaaaauauac      480

uauagcuuac uagaagacuu ccaaccagca gccgcaagug aaacaaacug ggaaagcgua      540

acaucaagca ucucaggagu aagcuauaac ucaccaucag uaacagaccc aacacuaaua      600

gcagacgcau uagacaaaaa aauagcagaa uucgacacag uagaagauuu auuaaaauac      660

uucaacccag aaucauggca agaagaccua gaaaauaugu accucgacac accaagauau      720

agaggaagaa gcuaucacga uagaaaauca aaaguagacc uagacagacu aaaugacgac      780

gcuaaacgau auaguuguac accaagaaac uacaguguca acauacgaga agaacuaaaa      840

cuagcaaacg uaguauucuu uccacgaugu cuacuaguac aaagaugugg aggaaacugc      900

ggaugcggaa caguaaauug gagaucaugc accugcaaca gcggaaaaac aguuaaaaaa      960

uaccacgaag uacuacaauu cgaaccuggc cacauaaaac gaaggggaag agcaaaaacc     1020

auggcacuag uagauaucca acuagaucau cacgagagau gugacuguau auguaguuca     1080

agaccaccaa gauaa                                                      1095


<210>  781
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  781
augguaacac acucaaaauu cccagcagca ggaaugucaa gaccauuaga cacaucauua       60

agacuaaaaa cauucucauc aaaaucagaa uaucaacuag uaguaaacgc aguaagaaaa      120

cuacaagaau caggauucua cuggucagca guaacaggag gagaagccaa ccuacuccua      180

ucagcagaac cagcaggaac cuuccuaaua agagacucau cagaccaacg acacuucuuc      240

acacuaucag uaaaaacaca auccggaaca aaaaaccuca gaauacaaug cgaaggagga      300

ucauucucac uacaaucaga cccacgcucc acacaaccag uaccaagauu cgacugcgua      360

cuaaaacuag uacaccacua caugccacca ccaggagccc caucauuucc aucaccacca      420

acagaaccau caucagaagu acccgaacaa ccaucagcac aaccacuccc cggaucacca      480

ccaagaagag cauacuacau auacucagga ggagaaaaaa uaccauuagu acuauccaga      540

ccauuaucuu caaacgucgc aacacuacaa caucuaugca gaaaaacagu aaacggacac      600

uuagacucau acgaaaaagu aacccaacua ccaggcccca uacgagaauu ccuagaccaa      660

uacgacgcac cacuauaa                                                    678


<210>  782
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  782
augguaccau cagcaggaca auuagcauua uucgcauuag gaauaguauu agcagcaugu       60

caagcauuag aaaauucaac aucaccacua ucagcagauc caccaguagc agcagcugua      120

guaucacauu uuaaugacug uccagauuca cauacucaau ucuguuuuca uggaacaugu      180

agauucuuag uacaagaaga caaaccagca uguguauguc auucaggaua uguaggagca      240

agaugugaac augcagauuu auuagcagua gucgcagcau cacaaaaaaa acaagcaaua      300

acagcauuag uaguaguauc aauaguagca uuagcaguac uaauuauaac auguguacua      360

auacauuguu gucaaguaag aaaacauugu gaauggugca gagcauuaau auguagacau      420

gaaaaaccau cagcauuauu aaaaggaaga acagcauguu gucauucaga aacaguagua      480

uaa                                                                    483


<210>  783
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  783
augccaccua gcggacucag auuauuaccc uuacuacucc cacuccuaug gcuacuagua       60

cuaacuccag gaagaccagc agcaggacua aguacaugua aaacuauaga cauggaauua      120

guaaaaagaa aaagaauaga agccauacgu ggacaaaucc uaucuaaauu gagacuagcc      180

ucaccuccau cacaaggaga aguaccacca ggaccccuac ccgaagcagu acuagcacua      240

uacaacucaa caagagauag aguagcagga gaaucagcag aaccagaacc agaaccagaa      300

gcagauuauu acgcaaaaga aguaacacgc guauuaaugg uagaaacaca uaacgaaaua      360

uaugauaaau ucaaacaauc uacacacucu auauacaugu ucuuuaauac aucagaacuc      420

agagaagccg uacccgaacc aguauuauua ucaagagcag aacuaagacu ucuaagacua      480

aaacucaaag uugaacaaca cguagaacua uaccaaaaau acucaaacaa uucuuggaga      540

uauuuaucua acagacuacu agcccccuca gacuccccug aauggcuauc auucgacgua      600

acaggaguag ucagacaaug guuaucuaga ggaggagaaa uagaaggauu ccgacuuuca      660

gcacacuguu cuugugauag ucgcgacaac acauuacaag uagacauaaa cgguuucaca      720

acuggacgua gaggagaccu ugcaacaaua caugguauga acagaccauu cuuacuacua      780

auggcaacac cacucgaacg agcacaacau cuacaauccu cacgccacag acgagcccua      840

gacacaaacu acugcuucuc aucaaccgaa aaaaauuguu gcguaagaca auuauacaua      900

gauuucagaa aagaccuagg auggaaaugg auacaugaac cuaaaggaua ccacgccaau      960

uuuuguuuag gcccaugucc auacauaugg ucacuagaca cacaauacuc uaaaguauua     1020

gcucuauaca accaacacaa cccaggcgca ucagcagcac caugcugugu uccacaagcu     1080

uuagaaccau uaccaaucgu auauuacgua ggaagaaaac ccaaaguaga acaauuauca     1140

aacaugauag ucagaucaug uaaaugcucu uaa                                  1173


<210>  784
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  784
augcauuacu gcguacuauc agcauuccua auacuacacc uaguaacagu agcauuaucc       60

cuaucaacuu gcuccacccu agacauggac caauuuauga gaaaacgcau agaagcaaua      120

agaggacaaa uuuuaucaaa acucaaacua acaagcccac cagaagacua cccagaacca      180

gaagaaguac caccggaagu cauuucaaua uacaauucaa caagagaccu acuacaagaa      240

aaagcaucaa gaagagcugc agcaugugaa agagaacgca gcgacgaaga auacuacgca      300

aaagaaguau acaaaaucga caugccucca uucuucccaa gcgaaaacgc aauaccacca      360

acauucuauc gaccauauuu uagaauagua agauucgacg ucucagccau ggaaaaaaau      420

gcuagcaauu uaguaaaagc agaauuuaga guuuucagac uacaaaaccc aaaagcacga      480

guccccgaac aacgaauaga auuauaccaa auacuaaaau caaaagaccu aacaucccca      540

acacaaagau acauagacuc aaaaguaguu aaaacccgag cagaaggcga auggcuaucu      600

uucgauguaa cagacgcagu acacgaaugg uuacaccaca aagauagaaa ccuagguuuc      660

aaaauaucuc uccacugccc augcugcaca uucguaccau ccaacaacua cauaauacca      720

aacaaaucug aagaauuaga agcaagauuc gcaggaauag acgguacauc aaccuacaca      780

ucaggagauc aaaaaacaau aaaauccaca agaaaaaaaa auucaggaaa aacaccacac      840

cuacuacuaa ugcuacuacc aagcuacaga uuagaaucac aacaaacaaa cagacgaaaa      900

aaaagagcac uagaugcagc auacugcuuc agaaacguac aagacaacug cugucuccgc      960

ccacuauaca uagauuucaa acgagauuua ggauggaaau ggauacacga acccaaagga     1020

uauaacgcca acuucugcgc aggagcaugc ccauauuuau ggucauccga cacccaacac     1080

uccagagucc uaucucucua caacaccaua aacccagaag caucagcauc acccugcugu     1140

guaucccaag acuuagaacc acuuacaaua uuauacuaca uaggaaaaac accaaaaaua     1200

gaacaacuau caaacaugau agucaaaucc uguaaaugcu cauaa                     1245


<210>  785
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  785
augaaaaugc acuuacaaag agcauuaguu guacuagcac uucucaacuu ugcaacagua       60

ucacuaucau uaucaaccug cacaacacua gacuuuggac acauaaaaaa aaaacgagua      120

gaagccauaa gaggacaaau acuaucaaaa cuaagacuaa caucaccacc agaaccaacc      180

guaaugacac acgucccaua ccaaguauua gcccuauaca acaguacaag agaacuacuc      240

gaagaaaugc acggagaacg agaagaagga ugcacucaag aaaauacaga aucagaauac      300

uacgcaaaag aaauacacaa auuugauaug auacaaggau uagcagaaca caaugaacua      360

gccguaugcc caaaaggaau aacaucaaaa guauuuagau uuaacguauc aucagucgaa      420

aaaaaccgca caaaucuuuu cagagcagaa uuucgagugc uacgaguacc aaauccauca      480

ucaaaaagaa acgaacaacg cauagaacua uuucaaaucc uacgaccaga cgaacacaua      540

gcaaaacaaa gauacauagg aggcaaaaac cuccccacaa gagguaccgc agaaugguua      600

ucauucgaug ucaccgacac aguacgagaa ugguuacuaa gaagagaauc aaaccuaggc      660

uuagaaauau caauccacug cccaugccac accuuucaac caaauggaga cauauuagaa      720

aacauacacg aaguuaugga aauaaaauuc aaaggaguag auaaugaaga ugaccacgga      780

cgaggugauc uuggaagacu aaaaaaacaa aaagaccacc acaacccaca ucuaauauua      840

augaugauac cuccacacag auuagacaac cccggacagg gaggacaaag aaaaaaaaga      900

gcacuagaua caaacuauug cuucagaaac cuagaagaaa acugcugcgu cagaccuuua      960

uacauagauu ucagacaaga ucucggaugg aaaugggucc acgaaccaaa aggauacuau     1020

gcaaacuuuu gcuccggccc cugcccauau cuacgaucag cagacacaac acacucaaca     1080

guacucggac uuuauaacac ucuaaacccc gaagcauccg ccuccccaug cuguguucca     1140

caagacuuag aaccacuaac aauauuauac uauguaggac gaacaccaaa aguugaacaa     1200

uuaagcaaca ugguaguaaa aucaugcaaa uguagcuaa                            1239


<210>  786
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  786
auggcacccg uagcugucug ggcagcauua gcaguuggau uagaauuaug ggcagcugcc       60

cacgcacuac cagcccaagu agcauucaca ccuuacgccc cagaaccugg aucuaccugc      120

agacuaagag aauauuacga ucaaacagcu caaauguguu guucaaaaug uucaccaggc      180

caacaugcaa aaguauucug uacaaaaaca ucagauacag uaugugauuc augcgaagau      240

ucaacuuaua cacaauuaug gaauuggguu cccgaaugcc uauccugugg aucaagaugu      300

ucaucagauc aaguagaaac ccaagcaugu acaagagaac aaaauagaau auguacaugc      360

agaccagguu gguauugugc acuaagcaaa caagaaggau gcagauuaug ugccccauua      420

agaaaauguc gaccaggcuu cggaguagca cgaccuggaa ccgaaaccuc ugauguagua      480

ugcaaaccau gugcaccagg aacauuuuca aacacaacau cuucaacaga cauaugcaga      540

ccacaccaaa uauguaacgu uguagcaaua ccuggcaaug ccucaaugga ugcaguuugu      600

acaucaacau ccccaacaag aucuauggca ccaggagccg uacauuuacc acaaccaguu      660

aguacucgau cacaacauac ccaacccaca cccgaaccau ccacugcucc guccaccuca      720

uuccuacuac caaugggacc cucuccacca gcugaagguu cuacaggaga cuucgcacua      780

ccaguuggau uaauaguagg aguaaccgca cuaggacuuc uaaucauagg aguaguuaau      840

uguguaauca ugacucaagu uaaaaaaaaa ccuuuauguu uacaacgaga agcaaaagua      900

ccacauuuac cggcagauaa agcaagagga acucaaggac cagaacaaca acaucuauua      960

auuacagcuc caucaucauc aucaucauca cuagaaucau cagcuucagc acuugaucga     1020

agagcaccua cacguaacca accacaagca ccaggugugg aagcuucagg ugcaggagaa     1080

gcaagagcaa guacaggauc aucagacagu ucaccaggag gucauggaac acaaguaaau     1140

guaacuugua uaguaaaugu cuguagcuca ucagaucauu caucccaaug cucaucucaa     1200

gccuccucaa caaugggaga cacagauucc ucuccaucag aaucaccaaa agacgaacaa     1260

guaccauuuu caaaagaaga augugccuuc agaucacaac uagaaacacc agaaacuuua     1320

uuaggaucaa cugaagaaaa accgcuaccc uuaggaguac cagacgccgg aaugaaaccc     1380

ucuuaa                                                                1386


<210>  787
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  787
augccaguaa ugagauuauu uccauguuuu cuacaauuau uagcaggauu agcacuacca       60

gcaguaccac cacaacaaug ggcauuauca gcaggaaaug gaaguucaga aguagaagua      120

guaccauuuc aagaagugug gggaagauca uauuguagag cauuagaaag auuaguagau      180

guaguaagug aauauccaag ugaaguagaa cauauguuuu caccaaguug uguaaguuua      240

uuaagaugua cagguuguug uggagaugaa aaccuacauu guguaccagu agaaacagca      300

aauguaacaa ugcaauuauu aaaaauaaga aguggagaua gaccaucaua uguugaauua      360

acauuuaguc aacauguaag augugaaugc agaccacuaa gagaaaaaau gaaaccagaa      420

agaagacgac caaaaggaag aggaaaaaga agaagagaaa aacaaagacc aacagauugu      480

cauuuaugug gagaugcagu accaagaaga uaa                                   513


<210>  788
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  788
augacagaua gacaaacuga uacagcaccg aguccgaguu aucauuuauu accaggaaga       60

aggagaacag uagaugcagc agcaucaaga ggacaaggac cugaaccagc accaggagga      120

gggguagaag gaguuggagc uagaggagua gcauuaaaau uauuugucca guuauuagga      180

ugcaguagau uuggaggagc cguaguaagg gcaggagaag cagaaccauc aggggcagca      240

cgaagugcau caaguggaag agaagaacca caaccagaag aaggagaaga agaagaggag      300

aaagaagaag aaagaggacc acaauggcgg cugggugcga gaaaaccagg aaguuggaca      360

ggagaagcag caguaugcgc agauucagcu cccgcagcga gagcaccuca agcauuagca      420

agagcaagcg gaagaggagg aagaguagca agaagaggag cagaagaauc agggccaccu      480

cauagcccaa guagaagggg uagugcaagu agagcaggac caggaagagc aagcgaaaca      540

augaauuuuu uauuaagcug gguacauugg ucauuagcgc uauuacuaua uuuacaucau      600

gcaaaaugga gccaagcagc accaauggca gaaggaggag gucaaaacca ucacgaagua      660

guaaaauuua uggauguuua ucaaagguca uacugccacc caauagaaac acuaguagau      720

auauuucaag aauacccaga cgaaauagaa uauauauuua aaccaagcug uguaccacua      780

augagaugug guggauguug caacgaugaa ggacuagaau guguaccaac agaagaaucu      840

aauauaacaa ugcagauaau gagaauaaaa ccacaccaag gacaacauau aggagaaaug      900

aguuuuuuac aacauaauaa augugaaugu agaccaaaaa aggauagagc aaggcaagaa      960

aaaaaaucag uaagaggcaa aggaaaagga caaaaaagga aaagaaaaaa gagcagauau     1020

aaaaguugga gcguguaugu aggagcaaga ugcugucuaa ugccaugguc acuaccagga     1080

ccucauccau guggaccaug uagugaacga agaaaacauc uauuuguaca ggauccacaa     1140

acauguaaau guagcuguaa aaauacagau aguagaugua aagcaaggca auuagaauua     1200

aaugaaagga cuuguagaug cgauaaaccu agaagguag                            1239


<210>  789
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  789
augaacuuuc uauuaagcug gguacauugg ucacuugcau uauuacuaua uuuacaucac       60

gcaaaaugga gccaagcagc accaauggca gaaggaggag gacaaaacca ucacgaagua      120

guaaaauuua uggauguaua ucaaaggagu uacugccauc caauagaaac acuaguggac      180

auauuccaag aauauccaga ugaaauagaa uauauauuua aaccaagcug uguaccacua      240

augagaugug gaggaugcug uaacgaugaa ggacuagaau gcguaccaac agaagaaagc      300

aauauaacaa ugcaaauaau gagaauaaaa ccacaccaag gacaacacau aggagaaaug      360

ucauucuuac aacauaacaa augcgaaugc agaccaaaaa aagaucgagc aagacaagaa      420

aaaaaaucag uaagaggaaa aggaaaagga caaaaaagaa aaagaaaaaa aagcagauac      480

aaaaguugga gcguauacgu aggagcaaga uguugcuuaa ugccaugguc acuaccagga      540

ccacacccau gcggacccug uagcgaaaga agaaaacauc uauucguaca agacccacaa      600

acaugcaaau gcucaugcaa aaacacagac ucaagaugua aagcaagaca acuagaacua      660

aaugaaagaa cauguagaug ugacaaacca agaagauaa                             699


<210>  790
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  790
augucaccau uacuaagaag acuauuacua gcagcauuau uacaacuagc accagcacaa       60

gcaccaguau cacaaccuga ugcaccagga caucaaagaa aaguaguauc auggauagau      120

guauauacaa gagcaacaug ccaaccaaga gaaguaguag uaccacuaac aguagaauua      180

augggaacag uagcaaaaca auuaguaccc ucaugcguaa caguacaaag augcggaggu      240

uguuguccag acgauggacu agaaugugua ccuacagguc aacaucaagu aagaaugcaa      300

auauuaauga uaagauaccc aaguucacaa uuaggagaaa ugucauuaga agaacauuca      360

caaugcgaau guagaccaaa aaaaaaagac ucagcaguaa aaccagacag agcagcaaca      420

ccacaccaua gaccucaacc aagaucugua ccaggauggg acucagcacc aggagcucca      480

ucaccagcag acauaacuca uccaacacca gcaccaggac ccucagcaca ugcagcucca      540

ucaacuacau cagcauuaac accaggacca gcagcagcug cugcagacgc agcagccuca      600

ucaguagcaa aaggaggagc auaa                                             624


<210>  791
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  791
augcaccuau uaggauuuuu cucaguagca uguucauuac uugcagcagc auuacucccc       60

ggaccaagag aagcaccagc ugcagcagca gcauucgaau caggacuaga ccuaagcgau      120

gcagaaccag acgcaggaga agcaacagca uaugcaagua aagaccuaga agaacaauua      180

agaaguguau caucaguaga cgaacuaaug acaguacucu accccgaaua cuggaaaaug      240

uacaaaugcc aauuaagaaa aggaggaugg caacacaaca gagaacaagc uaaccuaaac      300

ucaagaacug aagaaacaau aaaauuugca gcagcccacu acaauacaga aauauuaaaa      360

ucaaucgaua acgaauggcg aaaaacacaa uguaugccaa gagaaguuug uauagacgua      420

ggaaaagaau uuggaguugc aacaaauaca uuuuuuaaac caccaugcgu cucaguauac      480

agaugcggag gaugcugcaa uagcgaagga uuacaaugua ugaauacauc aacaagcuac      540

uuaagcaaaa cacuauuuga aauaacagua cccuuaucac aaggacccaa accaguuaca      600

auaaguuuug caaaucauac uucaugcaga uguaugagua aauuagaugu uuaucgccaa      660

guacauucaa uaauacgacg cagucuacca gcaacauuac cacaaugcca agcugcaaau      720

aaaacaugcc caacuaauua uauguggaau aaucacaucu gcagaugucu ugcacaagaa      780

gacuucaugu uuuccucaga ugcaggagac gauucaacag acggcuucca cgacauaugu      840

ggaccaaaua aagaacuaga ugaagaaaca ugucaaugcg ucugcagagc aggauuaaga      900

ccagcaucau guggaccaca caaagaauua gacaggaauu ccugccaaug uguauguaaa      960

aauaaacuau uuccaucaca augcggagcc aaucgagaau ucgacgaaaa uacaugccaa     1020

ugugucugua aaagaaccug ucccagaaau caaccauuaa acccuggaaa augugccugu     1080

gaaugcacag agucaccaca aaaauguuua cuaaaaggaa aaaaauucca ucaucaaaca     1140

ugcuccuguu acagaagacc cugcacaaac agacaaaaag caugcgaacc aggauucagc     1200

uacagugaag aaguaugcag auguguacca ucauauugga aacgaccaca aaugucauaa     1260


<210>  792
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  792
auguacagag aauggguagu aguaaacgua uucaugaugc uauacguaca auuaguacaa       60

gguuccucaa acgaacacgg cccaguaaaa agaucauccc aaagcacacu agaaagaucu      120

gaacaacaaa uaagagcagc aucuucacua gaagaacuuu uaagaauaac acacucagaa      180

gacuggaaac uauggagaug cagacuaaga cuaaaaucau ucacaucuau ggacagcagg      240

uccgcaaguc acagaucaac cagauucgcc gcaacauuuu augacauaga aacacucaaa      300

guaauagacg aagaauggca aagaacacaa ugcaguccaa gagaaacaug uguagaagua      360

gccucagaac uaggaaaaag cacuaacaca uucuucaaac caccaugcgu aaauguauuc      420

agaugcggcg gauguugcaa cgaagaaucu cucauaugua ugaacacaag uacaucauac      480

aucucaaaac aacuauucga aauaucaguc ccauuaacau caguaccaga acuaguacca      540

guaaaaguag caaaccacac aggauguaaa ugccuaccaa cagcaccaag acacccauac      600

aguaucauaa gaagaucaau ccaaauacca gaagaagacc gaugcuccca cucaaaaaaa      660

uuaugcccaa uagacaugcu augggauuca aacaaaugca aaugcguacu acaagaagaa      720

aacccauuag caggaacaga agaccacucu cacuuacaag aaccagcauu augcggacca      780

cauaugaugu ucgacgaaga uagaugugaa uguguaugca aaacuccaug cccaaaagac      840

cuaauacaac acccaaaaaa cugcucaugu uucgaaugca aagaaucucu agaaacaugc      900

ugccaaaaac acaaauuauu ucacccagac acaugcucau gcgaagacag augcccuuuc      960

cacaccagac caugugccag cggaaaaaca gcaugugcaa aacacuguag auuuccaaaa     1020

gaaaaacgag cagcccaagg accacacuca agaaaaaauc cauaa                     1065


<210>  793
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  793
auggccguga uggcacccag gacccugguc cuccuguuga gcggcgcccu ggcgcucacu       60

cagaccuggg cc                                                           72


<210>  794
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  794
auggacgcca ugaagagggg ccugugcugu gugcuccugu ugugcggggc agucuucgug       60

agccccucc                                                               69


<210>  795
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  795
augggcgugc acgagugccc cgccuggcug uggcuccugu ugagccugcu cucccugcca       60

uuggggcugc cgguccucgg u                                                 81


<210>  796
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  796
augaaguggg ugaccuucau cagccugcuc uuucuguucu ccagugccua cagc             54


<210>  797
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from 
       Artificial____cleavage site-Furin

<400>  797
aggcggcgca ggaagcgg                                                     18


<210>  798
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  798
auggacagcg augagaccgg cuucgaacac uccgggcugu gggugagugu ccucgccggu       60

cuguugcugg gcgcaugcca ggcccauccc aucccagaca gcuccccgcu ccugcaauuu      120

gggggccagg ugaggcagcg guacuuguau acugaugacg cgcagcaaac cgaggcccac      180

cuggaaauuc gcgaggaugg uacgguaggg ggcgcagccg accagagucc cgaaagccuc      240

cugcagcuga aggcacucaa accaggcgug auccagauuc ugggggucaa gacuuccagg      300

uucuuguguc aacggcccga uggugcccug uacggcagcc uccauuuuga cccagaggcg      360

ugcuccuucc gcgagcugcu guuggaagau ggguauaacg uguaccagag ugaggcccac      420

ggccuccccc ugcaucugcc agguaauaaa agcccgcaca gggaccccgc accacggggg      480

cccgcccgcu uucucccacu gcccggcuug ccgcccgccc ugccagaacc cccaggcauc      540

cucgcacccc agccaccgga uguggggucc agcgaccccc ugaguauggu cgguccaucc      600

cagggcagga gccccuccua ugccaguuga                                       630


<210>  799
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  799
augcacagcu uucccccacu gcuccuguug cuguucuggg gcguggucuc ccauaguuuc       60

ccggccaccc ucgagacuca ggaacaagac guggaucugg uacagaagua cuuggagaaa      120

uauuacaacc ugaagaauga cgggaggcaa guggaaaaac ggcgcaacag cggucccguc      180

guggagaagc ucaaacagau gcaggaauuu uucggccuga aggugaccgg gaagccagau      240

gcagagacgc ugaaagucau gaagcagccc aggugcggcg ugccagacgu agcccaguuu      300

gugcucacug aggguaaucc ccggugggaa cagacccacc ugaccuaucg caucgagaac      360

uacacuccag auuugccgag ggcggacguc gaucaugcca uugaaaaagc auuccaacug      420

ugguccaaug ugacgccccu caccuuuacu aaggugagug aggggcaggc cgacaucaug      480

auuagcuucg uccggggcga ucaccgcgac aacuccccau uugauggccc cggggguaau      540

cuggcacaug ccuuccagcc aggccccggg aucggcggug acgcgcacuu ugaugaggac      600

gaaaggugga ccaacaauuu ccgggaguau aaccugcacc gcguggccgc acaugaauug      660

gggcacagcc ucggccuguc ccauaguacu gacauuggcg cccugaugua cccgagcuau      720

accuucuccg gggauguaca gcucgcccaa gacgauaucg acgguaucca ggcaauuuac      780

ggcaggagcc agaaucccgu gcaaccaauc gggccccaga ccccaaaagc cugugauagu      840

aagcugacgu uugacgcgau uacuaccauc cggggcgagg ucauguucuu uaaagaucgc      900

uucuacauga ggacuaaccc cuuuuaucca gaaguggagu ugaauuucau uuccguguuu      960

uggccgcagc ugcccaacgg ucucgaggcc gcauacgagu ucgccgaccg ggaugaaguc     1020

cgcuuuuuca agggcaauaa guauugggca gugcaggggc aaaacguacu gcacggcuac     1080

ccaaaagaca ucuauagcuc cuuuggguuc cccaggaccg ugaagcacau ugaugccgcc     1140

cugagugaag agaacaccgg uaaaacuuac uuuuucgucg cgaauaagua uuggcgguac     1200

gacgaauaca aacgcagcau ggacccaggc uaucccaaga ugaucgcaca ugauuucccg     1260

gggaucggcc acaaggugga cgccgucuuu augaaagaug guuucuuuua cuucuuucau     1320

ggcacgaggc aguauaaguu cgacccaaaa accaagcgga uuuugacucu ccagaaagcc     1380

aacuccuggu uuaauugcag gaagaacuga                                      1410


<210>  800
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  800
augcacagcu uucccccacu gcuccuguug cuguucuggg gcguggucuc ccauaguuuc       60

gugcucaccg aggggaaccc gaggugggaa cagacucacc ugaccuaccg gaucgagaau      120

uauacgcccg acuugccacg cgccgaugua gaccaugcaa uugaaaaggc cuuucaacug      180

uggagcaacg ugacuccccu caccuucacc aaagucuccg agggucaggc ggauaucaug      240

auuaguuuug ugaggggcga ccaccgggau aauagcccau ucgacgggcc cggcgguaac      300

cuggcccaug cauuucagcc agggccgggc aucggcgggg augcccacuu cgacgaagau      360

gagcgcugga cuaauaacuu uagggaguac aaucugcacc ggguggcagc ccaugaacuc      420

ggucacuccc ugggcuugag ccauuccacc gacauugggg cgcugaugua ucccaguuac      480

acguucagcg gcgaugucca gcucgcccaa gacgauaucg acgguaucca ggcaauuuau      540

gggcgcuccc agaacccagu gcagcccauc ggcccacaaa cucccaaggc cugcgacagc      600

aaacugaccu uugaugccau uacuaccauc aggggcgagg uaauguucuu caaggaccgg      660

uuuuacaugc gcaccaaucc guucuauccc gaaguggagc ugaacuuuau uagugucuuc      720

uggccacagu ugcccaaugg gcucgaggca gccuacgaau uugcggauag ggacgaggug      780

cgguucuuua aagguaacaa guacugggcc gugcagggcc agaauguccu gcacggguau      840

ccaaaggaua ucuacuccag cuucggcuuu ccccgcacgg ugaaacacau ugacgcagcc      900

cuguccgaag agaacacugg uaagaccuau uucuuuguag caaauaaaua cuggagguau      960

gaugaauaca agcggaguau ggacccaggc uauccgaaaa ugaucgccca ugauuucccc     1020

gggaucggcc acaaggugga cgccgucuuu augaaagaug gguucuucua cuuuuuccau     1080

gguacucgcc aauacaaguu ugacccaaag accaaaagga uucucacccu gcagaaggcg     1140

aacagcuggu ucaacugucg gaaaaauuga                                      1170


<210>  801
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  801
augaagaaaa acauccugaa gauucucaug gacagcuacu ccaaagagag uaagauccag       60

accgugaggc gggucacuag cgugucccug uuggccguau aucugaccau gaauacgagu      120

agccucgugc uggcaaaacc cauugaaaac acuaaugaua ccuccaucaa gaacgucgag      180

aaguugcgca augccccaaa cgaagagaau agcaaaaagg uggaagacuc caaaaacgau      240

aagguggagc acgucaaaaa uauugaggaa gcgaaggugg agcaaguagc cccggaagug      300

aaaaguaaga gcacccugag guccgcaagc aucgccaaca cuaauaguga gaaguacgac      360

uucgaguauc ucaacggccu guccuacacc gaacugacga aucucaucaa aaacauuaag      420

uggaaucaga ucaacgggcu guuuaacuau agcacugguu cccagaaauu cuuuggcgau      480

aagaaucggg uccaggcaau uaucaacgcc uugcaagaga gugggcgcac cuacacugcg      540

aaugacauga aaggcauuga aaccuucacc gaggugcuga gggccgguuu uuaucucggg      600

uacuacaacg auggccugag cuaucugaau gaccggaacu uccaggauaa gugcaucccc      660

gcaaugauug ccauccagaa gaauccaaac uuuaaauugg gcacggccgu gcaggacgaa      720

gucaucacuu cccucgggaa gcugauuggu aaugcaagcg ccaacgcgga ggugguaaau      780

aacugugugc ccguccugaa acaauuccgc gagaaucuca accaguacgc cccagauuau      840

gugaagggca ccgcagugaa ugaacugauc aaagggauug aguuugacuu caguggcgcc      900

gcauacgaaa aggaugucaa gacuaugccc ugguauggua aaaucgaccc auuuauuaac      960

gaguugaagg cccuggggcu cuacggcaac aucaccuccg ccaccgaaug ggcgagcgac     1020

gugggcaucu auuaccugag uaaauucggg cuguacucca cuaauaggaa cgauauugua     1080

cagagcuugg agaaggcagu ggacauguau aaauacggua agaucgccuu cgucgccaug     1140

gagcggauua cgugggauua ugacggcauc gggagcaaug gcaagaaagu ggaucaugac     1200

aaguuucucg augacgcaga aaaacacuac cugccgaaga ccuauacuuu cgauaacggu     1260

accuuuauua uccgcgccgg cgacaaaguc uccgaggaaa agaucaaaag gcuguacugg     1320

gcgagucggg agguaaagag ccaguuccau cgcguggugg ggaaugauaa ggcccucgaa     1380

gugggcaacg cagacgacgu ccugaccaug aaaauuuuua auucccccga ggaguauaag     1440

uucaacacua auaucaacgg ggugagcacg gauaauggug gcuuguacau ugaaccaagg     1500

gggaccuuuu acacuuauga gcggacuccc caacagagua ucuucucccu ggaggaacuc     1560

uuucgccacg aguacaccca uuaucugcag gccagguacc uggucgacgg cuuguggggu     1620

caaggcccau ucuaugagaa aaaccggcuc accugguuug augaagggac ggcagaguuc     1680

uuugccggca gcacccgcac uuccggggug cugcccagga agaguauucu gggcuaccuc     1740

gccaaagaca agguggauca ccgguauagc cugaagaaaa ccuugaacuc cgguuacgac     1800

gauagcgacu ggauguucua caauuauggg uucgcaguag cccacuaccu guaugaaaag     1860

gauaugccga cuuuuaucaa aaugaauaag gcgauucuca acaccgacgu gaaaaguuac     1920

gaugaaauca ucaagaagcu guccgacgau gccaacaaaa auacggagua ucagaaccau     1980

auucaggagc uggcagacaa guaccagggc gccgguaucc ccuuggucag cgacgauuau     2040

cugaaagacc acggcuacaa gaaagccucc gaaguguaca gugagauuag caaggcagcg     2100

ucccucacca auacuagcgu caccgccgag aaaagucaau auuucaacac uuuuacccug     2160

agggggacgu acaccggcga aacuuccaag ggggaguuca aggauuggga cgaaaugagc     2220

aaaaagcucg auggcacccu ggaguccuug gccaaaaaua gcuggagugg uuauaagacu     2280

cugaccgcau acuuuacgaa cuaucgcgug accagcgaca auaaagugca guacgaugua     2340

gucuuccaug gggugcucac ugacaacgcc gauaucucca auaacaaggc accaauugcc     2400

aaggugaccg gccccaguac uggcgcgguc gggcggaaua ucgaauuuag cgguaaagac     2460

uccaaggaug aggacggcaa aaucgugagc uacgacuggg auuucgggga cggcgccacc     2520

uccaggggua agaacagugu gcacgcauau aaaaaggccg ggacguacaa uguaacccug     2580

aaggucacug augacaaagg cgccaccgca acugagagcu uuaccauuga aaucaagaac     2640

gaagauacua ccacgccaau uaccaaagag auggagccca augacgauau caaggaagcc     2700

aacggcccaa uuguggaggg ggugacuguc aaaggugacc ugaacggcuc cgaugacgcg     2760

gauaccuucu auuuugacgu gaaggaagau ggggacguaa cuaucgaguu gccguacagu     2820

ggcagcucca auuucaccug gcugguguau aaagagggug acgaucagaa ccacaucgcc     2880

agcgggauug acaagaauaa caguaagguc ggcacguuca aauccaccaa gggccgccau     2940

uacguguuua ucuauaaaca cgauagcgca uccaauauua gcuacagucu caacaucaag     3000

gggcugggua augaaaaacu caaggagaag gaaaacaaug acuccagcga uaaagccacu     3060

gugauuccca acuucaauac cacuaugcag ggcagucugu ugggggacga uucccgggac     3120

uacuauagcu uugaggucaa ggaagagggc gaggugaaca ucgaacugga uaaaaaggac     3180

gaguucggug uaaccuggac gcugcaucca gaauccaaua uuaacgauag gaucaccuac     3240

gggcaagugg acggcaauaa agucagcaac aaggugaagc uccgccccgg caaauauuac     3300

cuguuggugu auaaguacag ugggagcggu aacuaugagc ugcgggucaa uaaauga        3357


<210>  802
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  802
augaaguggg ugaccuucau cagccugcuc uuucuguucu ccagugccua cagcauugca       60

aacacuaauu ccgagaaaua ugacuuugaa uacuugaacg gccugaguua uaccgagcuc      120

acgaaucuga ucaagaacau uaaauggaau cagaucaacg gguuguucaa uuacagcacu      180

gguucccaaa aguuuuucgg cgauaaaaac aggguccagg ccauuaucaa ugcgcugcag      240

gaaagcgggc ggaccuauac cgccaacgac augaagggca ucgagacuuu uaccgaagug      300

cuccgcgcag guuucuaccu gggguauuac aaugauggcc uguccuaccu caacgacagg      360

aauuuucagg auaagugcau ucccgccaug aucgcaauuc agaaaaaccc aaauuucaag      420

cugggcacgg ccguacagga cgaggugauc acuagcuugg ggaaacugau ugguaacgcg      480

agcgccaacg cagaggucgu gaauaacugu gugccggucc ucaagcaguu ucgggaaaau      540

cugaaccagu augcccccga uuacgugaaa ggcaccgccg uaaaugagcu gaucaagggg      600

auugaguucg acuucuccgg cgcagccuau gaaaaagaug ugaagacuau gccaugguac      660

gguaagaucg accccuuuau caacgaguug aaagcgcucg ggcuguaugg caauauuacc      720

agcgccaccg aaugggcaag ugaugucggc aucuacuauc uguccaaguu cgggcucuac      780

agcacgaacc gcaaugacau ugugcaaucc cuggagaaag ccguggauau guacaaguau      840

gguaaaaucg cauuugucgc cauggaaagg auuacuuggg acuacgacgg caucgggagu      900

aacggcaaga agguggauca cgacaaauuc uuggaugacg ccgagaagca uuaucugcca      960

aaaaccuaca cuuuugauaa ugguaccuuc aucauucggg cgggcgacaa gguaagcgaa     1020

gagaaaauca agcgccucua uugggcaucc agggagguga agagucaguu ucaccggguc     1080

guggggaacg auaaagcccu ggaagugggc aaugccgacg auguccugac caugaagauu     1140

uucaacaguc ccgaggaaua caaauuuaau acuaacauca acgggguguc cacggacaau     1200

gguggcuugu auauugagcc acgcgggacc uucuacacuu acgaaaggac cccgcagcag     1260

agcaucuuua gucucgagga gcuguuccgg caugaauaua cccacuaccu gcaagcacgc     1320

uaucucguag auggccugug gggucagggc cccuuuuacg agaagaacag guugacuugg     1380

uucgacgaag ggacggccga guucuuugcg ggcuccaccc ggacuagcgg ggugcugcca     1440

cgcaaaagca uccucggcua ucuggccaag gacaaggucg aucauaggua cucccugaaa     1500

aagaccuuga auagugguua ugacgauagc gacuggaugu ucuacaacua cggguuugca     1560

guggcccacu aucucuacga aaaagauaug cccaccuuca uuaagaugaa uaaagcaauc     1620

cugaacacug acgucaaguc cuaugaugag auuaucaaaa agcugagcga cgaugccaau     1680

aagaacacgg aguaccagaa ucacauucaa gaacucgccg acaaauauca gggcgcaggu     1740

aucccacugg ugagugauga cuacuugaag gaucauggcu auaaaaaggc cuccgaggug     1800

uacagcgaaa uuuccaaagc ggccagucug accaacacua gcguaaccgc agagaagucc     1860

caguacuuua auacuuucac ccuccggggg acguauaccg gcgagacuag caagggggaa     1920

uuuaaagacu gggacgagau gaguaagaaa cuggauggca cccuggaauc cuuggccaag     1980

aacagcuggu ccgguuacaa aacucugacc gccuauuuca cgaauuaccg cgugaccagu     2040

gacaacaagg uccaguauga uguggucuuu cacggggugc ucacugacaa ugcagauauc     2100

agcaacaaca aggcgcccau cgccaaagug accggcccgu ccacuggcgc aguagggagg     2160

aauauugagu ucagcgguaa ggacaguaaa gaugaagacg gcaagaucgu guccuacgau     2220

ugggacuuug gggauggcgc caccagccgg gguaaaaacu ccguccaugc cuacaagaaa     2280

gcagggacgu auaaugugac ccugaagguc acugacgaca agggcgccac cgcgacugag     2340

agcuucacca uugagaucaa aaacgaagau acgaccacuc ccauuaccaa ggagauggaa     2400

ccaaaugacg auaucaaaga ggccaacggc cccaucgugg aaggggugac uguaaagggu     2460

gaccucaaug gcagugauga cgcagauacc uucuacuuug acgucaaaga ggauggggac     2520

gugacuauug agcugccaua uagcggcucc aguaacuuca ccugguuggu guacaaggaa     2580

ggugaugacc aaaaucacau cgccagcggg auugauaaga acaauuccaa agucggcacg     2640

uuuaagagca ccaaaggcag gcacuaugug uucaucuaca agcaugacuc cgccaguaac     2700

auuagcuauu cccugaauau caaagggcuc gguaacgaga agcugaagga aaaagagaau     2760

aacgacagua gcgauaaggc aacugugauc cccaacuuua auaccacuau gcagggcucc     2820

cuguuggggg acgauagccg cgacuacuac aguuucgaag uaaaagagga gggcgaaguc     2880

aacauugagc uggauaagaa agacgaauuu ggugugaccu ggacgcucca cccagagucc     2940

aauaucaacg aucggauuac cuaugggcaa guggacggca auaaggucag caacaaagug     3000

aagcugaggc cgggcaagua cuaucuccug guauacaaau auuccgggag cgguaauuac     3060

gaguugcgcg ugaacaagug a                                               3081


<210>  803
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  803
augaaguggg ugaccuucau cagccugcuc uuucuguucu ccagugccua cagcaugaaa       60

aagaacauuu ugaaaauccu gauggacucc uauaguaagg agagcaaaau ucagacuguc      120

aggcggguga ccuccguaag ccuccuggca guguacuuga cgaugaauac uuccagucug      180

guccucgcca agcccaucga aaacaccaau gauaccagca uuaagaacgu ggagaaacug      240

cgcaaugcgc caaacgaaga aaauuccaag aaaguggaag acagcaagaa cgauaaaguc      300

gagcacguga agaauaucga ggaagccaaa guagagcaag uggcaccgga agucaagagu      360

aaguccacuc ugaggagcgc cucccggcgc aggcggaaac gcaucgcaaa caccaauagu      420

gagaaguaug acuuugagua ccucaacggc cugagcuaua cggaauugac uaaucugauu      480

aaaaacauca aguggaauca gauuaacggu cucuucaacu acuccaccgg gagccagaaa      540

uuuuucggcg auaagaauag ggugcaggcc aucauuaacg cgcugcaaga gagugggcgg      600

acuuauaccg ccaaugacau gaagggcauc gaaaccuuua cggaggugcu gcgcgcaggu      660

uucuacuugg gguacuauaa cgauggccuc uccuaccuga augacaggaa cuuucaggau      720

aaaugcauuc ccgccaugau cgccauccag aagaauccaa acuucaaacu gggcacugca      780

guccaggacg aagugauuac cagccucggg aagcugaucg guaaugccag ugcgaacgcc      840

gagguaguga auaacugugu ccccguguug aaacaauuuc gggagaaucu gaaccaguau      900

gcaccagauu acgugaaggg cacugccguc aaugaacuca uuaaggggau cgaguucgac      960

uucuccggcg cagccuauga aaaagaugug aagaccaugc ccugguacgg uaaaauugac     1020

ccauuuauca acgagcugaa ggcccugggg uuguauggca acaucaccag cgcgacugaa     1080

ugggcaagcg acguaggcau uuacuaccuc uccaaauucg ggcuguauag uacgaaucgc     1140

aacgauaucg ugcagagccu ggagaaggcc gucgacaugu acaaguaugg uaaaauugcc     1200

uuuguggcaa uggagaggau caccugggau uacgacggca uuggguccaa uggcaagaaa     1260

gucgaucaug acaaguuccu cgaugacgcc gaaaaacacu aucugccgaa gacuuacacc     1320

uuugauaacg guaccuucau cauccgggcg ggcgacaaag ugagcgagga aaagauuaag     1380

cgcuuguauu gggccaguag ggaggugaaa ucccaguuuc aucggguagu ggggaaugau     1440

aaggcacugg aagucggcaa cgccgacgac gugcucacua ugaaaaucuu caauagcccc     1500

gaggaguaca aguuuaacac gaauauuaac ggggucucca ccgauaaugg uggccuguac     1560

aucgaaccac gcgggacuuu cuauaccuac gagaggacuc cccaacagag uauuuuuagc     1620

cuggaagagu uguuccggca cgaguauacc cauuaccucc aggcaaggua ucugguggac     1680

ggccuguggg gucaaggccc auuuuacgag aaaaaccgcc ucacgugguu cgaugagggg     1740

accgccgagu ucuuugccgg cuccacucgg accagcgggg ugcugcccag gaagaguauc     1800

uugggcuauc uggcaaagga caaaguagau caccgcuacu cccucaagaa aacucugaau     1860

agcgguuacg acgauuccga cuggauguuc uauaacuacg gguuugccgu ggcgcacuau     1920

cuguacgaaa aggauaugcc gaccuucauu aaaaugaaua aggccaucuu gaacacggac     1980

gucaagaguu augaugaaau cauuaaaaag cugagcgacg augcaaacaa aaauaccgag     2040

uaccagaacc auauccagga gcucgccgac aaguaucagg gcgccgguau uccccuggug     2100

uccgacgauu accucaaaga ccacggcuac aagaaagcaa gcgaagucua uagugagauc     2160

uccaaggcgg ccagccugac uaauaccucc gugacugcag aaaagagcca auacuuuaac     2220

accuucacgu ugcgggggac cuauacuggc gagaccagua aaggggaauu uaaggauugg     2280

gacgagauga gcaaaaagcu ggauggcacu cucgaguccc uggccaaaaa uaguuggagc     2340

gguuacaaga cccugacggc cuauuucacc aacuacaggg ugacuuccga caauaaggua     2400

caguacgaug ucguguuuca ugggguguug accgacaacg cagauauuag caauaacaaa     2460

gccccaaucg cgaaggucac uggccccucc accggcgccg uggggcgcaa uaucgaguuc     2520

agugguaaag acagcaagga ugaagacggc aaaauugugu ccuaugacug ggauuuuggg     2580

gacggcgcaa cgagucgggg uaagaacagc guacacgccu acaagaaagc cgggaccuau     2640

aaugucacuc ugaaggugac cgaugacaaa ggcgcaacug ccaccgaauc cuucacuauc     2700

gagauuaaga acgaagauac cacgacccca aucacuaaag agauggagcc caaugacgau     2760

auuaaggaag cgaacggccc aaucguggag ggggucaccg ugaaagguga ccucaacggc     2820

agcgaugacg ccgauacuuu cuacuuugac guaaaggaag auggggacgu gaccaucgag     2880

cugccguaua guggcuccag caauuucacg uggcucgucu acaaggaggg ugacgaucag     2940

aaccacauug cauccgggau cgacaaaaau aacagcaagg ugggcaccuu uaaaaguacu     3000

aagggcaggc auuauguguu cauuuacaaa cacgauuccg ccagcaauau caguuacucc     3060

cugaacauua agggguuggg uaaugaaaag cugaaagaga aggaaaacaa ugacagcucc     3120

gauaaagcaa ccgucauccc caacuuuaau acuaccaugc agggcagccu gcucggggac     3180

gauagucggg acuauuacag cuucgaggug aaggaagagg gcgagguaaa cauugaacug     3240

gauaaaaagg acgaguuugg ugugacgugg accuugcauc cagaauccaa uaucaacgau     3300

cgcaucacuu augggcaagu cgacggcaau aaggugagua acaaagugaa gcugaggccc     3360

ggcaaauacu aucuccuggu cuacaaguau agcggguccg guaacuacga gcuccgggug     3420

aauaaauga                                                             3429


<210>  804
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  804
augaacuucc ugaagaucau ucucaauagg ggcaaaacca ugaagcggaa augccugagc       60

aagcgcuuga ugcuggccau cacuauggca accauuuuua cggugaacuc cacucucccc      120

aucuacgccg cggucgacaa aaauaacgcc accgcagccg ugcagaauga gaguaagagg      180

uauaccguaa gcuaccugaa gacuuugaac uauuacgauc ugguggaccu ccuggucaaa      240

accgaaauug agaaucugcc agaucucuuc caauauucca gugacgcaaa ggaauuuuac      300

gggaacaaaa cgcggaugag cuucaucaug gaugagaucg gucgcagggc cccgcaguau      360

acugaaauug accacaaggg cauccccacc cugguggagg ugguccgggc gggguuuuac      420

uugggcuucc auaauaaaga gcugaacgaa auuaauaagc gcuccuuuaa agagagggug      480

aucccaagca uucucgccau ccagaagaac cccaauuuca agcuggguac ugaaguacag      540

gauaaaauug uguccgcaac cgggcuguug gccggcaacg agaccgcccc acccgagguc      600

gugaauaacu uuacgccaau ccuccaagac uguaucaaga acauugaucg guacgcacug      660

gacgaucuga aaaguaaggc ccucuucaau gugcuggcgg ccccgacuua ugacaucacc      720

gaauacuugc gcgcaacuaa agagaagccc gaaaacaccc caugguaugg caagauugau      780

ggguuuauca augagcugaa aaagcucgcc cuguacggua aaauuaacga caauaacagc      840

uggaucaucg acaauggcau uuaucacauc gcaccccugg ggaaguugca uuccaacaau      900

aaaauuggca ucgaaacccu cacugagguc augaaggugu acccauaucu gagcaugcag      960

caucugcaga gugccgauca gauuaagagg cacuacgacu ccaaagaugc cgaggguaac     1020

aagauccccc ucgacaaauu caagaaagaa gggaaggaga aguacugccc gaaaacguau     1080

accuucgaug acggcaaggu aaucauuaaa gcgggcgcac ggguggaaga ggaaaagguc     1140

aaacgccugu acugggccag caaggaggug aauagucaau uuuucagggu guaugggauc     1200

gauaaacccu uggaggaagg uaacccagac gauauucuga cuauggucau cuacaauagu     1260

cccgaggaau auaagcucaa cagcgugcug uacggcuaug acaccaauaa cgggggcaug     1320

uacauugagc cagaagguac cuuuuucacu uacgagcggg aggcccagga auccacguau     1380

acccuggagg aauuguuucg ccacgaguac acucacuauc uccagggcag guacgcagua     1440

cccgggcagu ggggccggac caagcuguau gauaacgacc gccugaccug guacgaggaa     1500

gggggugccg aacucuucgc gggcagcacu aggacgagug ggauccugcc acggaaaucc     1560

auugugagca auauccauaa caccacuagg aauaaccgcu auaaguugag ugacaccguc     1620

cacuccaaau acggcgccag cuuugaguuc uacaauuaug cauguauguu uauggauuac     1680

auguauaaca aggacauggg uauccugaau aaacucaacg aucuggccaa gaauaacgac     1740

guggauggcu acgacaauua uauucgggau cugagcucca acuacgcauu gaaugacaag     1800

uaucaagauc auaugcagga gaggaucgac aacuacgaaa aucugacugu cccguucgug     1860

gccgaugacu accucgugcg ccacgccuau aaaaacccca acgagauuua cagugagauc     1920

agcgaaguag caaagcugaa agaugccaag uccgagguga aaaagagcca guauuuuagu     1980

accuucacgc uccggggguc cuacaccggc ggggcgagca agggcaaacu ggaagaccaa     2040

aaggccauga auaaauuuau ugacgauucc uugaagaaac uggacacuua uaguuggagc     2100

gguuacaaga cccucacugc auacuucacc aacuauaaag ucgauuccag caauagggug     2160

acguacgacg ucguguucca cggguaucug ccaaacgagg gcgauaguaa aaauucccug     2220

cccuacggua agaucaacgg caccuauaag gggacugaaa aggagaaaau caaguuuagc     2280

uccgagggca guuucgaccc agaugggaaa auugugagcu acgaauggga cuuuggcgau     2340

gguaauaagu ccaacgagga aaaucccgag cauagcuaug acaagguagg gaccuacacu     2400

gugaaauuga aggucaccga ugacaaaggc gaaaguuccg ugagcacgac cacugccgag     2460

aucaaggacc uguccgagaa caaacucccg gucauuuaca ugcacgugcc aaagagcggc     2520

gcccugaauc agaagguggu auucuauggg aaagguaccu acgaucccga cggcaguauc     2580

gcaggguauc agugggauuu uggcgacggu agcgauuucu ccagugaaca gaaccccagc     2640

caugucuaca cuaagaaagg ggaguauacc gugacgcucc gcgugaugga cuccagcggc     2700

caaauguccg aaaagaccau gaaaauuaag aucacugauc cagucuaccc caucggcacc     2760

gagaaagagc caaauaacag uaaggaaacu gcgagcgggc cgauugugcc cgguauccca     2820

guguccggca ccauugagaa uacuuccgac caggauuauu uuuacuucga cguaaucacc     2880

cccggggaag ucaagauuga uaucaacaaa cugggcuacg guggggccac guggguggug     2940

uaugacgaga acaauaacgc agucagcuac gccaccgaug acggccagaa uuuguccggc     3000

aaguuuaaag ccgacaagcc agggcgguau uacauucacc uguauauguu caacgguagc     3060

uacaugcccu auaggaucaa uaucgaaggc aguguggggc gguga                     3105


<210>  805
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  805
augaagagga aaugccugag caagcggcuc augcuggcca ucaccauggc aacuauuuuc       60

accgugaacu ccacguugcc caucuacgcc gcggucgaca aaaauaacgc cacugcagcc      120

gugcagaaug agaguaagcg cuauaccgua agcuaccuga aaacccucaa cuauuacgau      180

cugguggacu ugcuggucaa gacugaaauu gagaaucucc cagaucuguu ucaauauucc      240

agugacgcaa aggaguucua cggcaacaaa accaggauga gcuuuaucau ggaugaaauu      300

gggcggcgcg ccccgcagua uacggaaauc gaccacaagg guauccccac ucugguggag      360

guggucaggg cgggcuucua ccucggguuu cauaauaaag agcugaacga aauuaauaag      420

cgguccuuca aagagcgcgu gaucccaagc auuuuggcca uccagaagaa ccccaauuuu      480

aaacugggca ccgaaguaca ggauaagauu guguccgcaa cuggucuccu ggccgggaac      540

gagaccgccc cacccgaggu cgugaauaac uucaccccaa uccugcaaga cuguauuaag      600

aauaucgaua gguacgcauu ggacgaucuc aaaaguaagg cccuguuuaa cgugcuggcg      660

gccccgacgu augacaucac ugaauaccuc cgggcaacca aagagaagcc cgaaaacacu      720

ccaugguaug gcaaaauuga uggcuucauc aaugagcuga agaaguuggc ccuguacggg      780

aaaauuaacg acaauaacag cuggaucauu gacaauggua ucuaucacau cgcaccccuc      840

ggcaagcugc auuccaacaa uaaaauuggg aucgaaaccc ugaccgaggu caugaaggug      900

uacccauauu ugagcaugca gcaccuccag agugccgauc agauuaaacg ccauuacgac      960

uccaaggaug ccgagggcaa caagaucccc cuggacaaau uuaagaaaga agguaaggag     1020

aaauacugcc cgaagacuua uacguucgau gacgggaagg uaauuaucaa agcgggcgca     1080

aggguggaag aggaaaaggu caaacggcug uacugggcca gcaaggaggu gaauagucaa     1140

uucuuucgcg uguauggcau cgauaaaccc cucgaggaag ggaacccaga cgauauucug     1200

accaugguca ucuacaauag ucccgaggaa uauaaguuga acagcgugcu guacgguuau     1260

gacacuaaua acggcgggau guacauugag ccagaaggca ccuucuuuac cuacgagagg     1320

gaggcccagg aauccacuua uacgcucgag gaacuguucc ggcacgagua cacccacuau     1380

cugcaggguc gcuacgcagu acccggccag ugggggagga cuaaauugua ugauaaugac     1440

cggcucaccu gguacgagga aggcggggcc gagcuguuug cggguagcac ccgcacuucc     1500

ggcauccugc caaggaaguc cauugugagc aacauccaua acacgacccg gaauaacagg     1560

uauaagcuca gugacacugu ccacuccaaa uacggggcca gcuucgaauu uuacaauuau     1620

gcauguaugu ucauggauua cauguauaac aaggacaugg gcauucugaa uaaauugaac     1680

gaucuggcca agaauaacga cguggauggu uacgacaauu auauccgcga ucucagcucc     1740

aacuacgcac ugaaugacaa auaucaagau cauaugcagg agcggaucga caacuacgaa     1800

aaucugaccg ucccguuugu ggccgaugac uacuugguga ggcacgccua uaagaacccc     1860

aaugagauuu acagugagau cagcgaagua gcaaagcuga aagaugccaa guccgaggug     1920

aaaaagagcc aguauuucag uacuuuuacc cuccgcggcu ccuacacggg cggcgcgagc     1980

aaagggaagc uggaagacca aaaggccaug aacaaauuca uugacgauuc ccucaagaaa     2040

cuggacaccu auaguuggag cggcuacaag acuuugaccg cauacuuuac uaacuauaaa     2100

gucgauucca gcaaucgggu gaccuacgac gucguguucc acgguuaucu gccaaacgag     2160

ggggauagua aaaauucccu ccccuacggc aagaucaacg guacguauaa gggcaccgaa     2220

aaggagaaaa uuaaguucag cuccgagggg aguuuugacc cagauggcaa aaucgugagc     2280

uacgaauggg acuucgggga uggcaauaag uccaacgagg aaaaucccga gcauagcuau     2340

gacaaaguag guacuuacac cgugaagcug aaggucacug augacaaagg ggaaaguucc     2400

gugagcacca cgaccgccga gaucaaggac cuguccgaga acaaauugcc ggucauuuac     2460

augcacgugc caaagagcgg cgcccugaau cagaaagugg uauuuuaugg caaggggacu     2520

uacgaucccg acgguaguau cgcaggcuau cagugggauu ucggggacgg cagcgauuuu     2580

uccagugaac agaaccccag ccaugucuac accaagaaag gugaguauac ugugacccuc     2640

agggugaugg acuccagcgg gcaaaugucc gaaaagacga ugaaaauuaa gaucaccgau     2700

ccagucuacc ccauuggcac ugagaaagag ccaaauaaca guaaggaaac cgcgagcggc     2760

ccgaucgugc ccgggauccc aguguccggu acuauugaga auaccaguga ccaggauuau     2820

uucuacuuug acguaaucac ucccggcgaa gucaaaauug auaucaacaa gcugggguac     2880

ggcggugcca ccuggguggu guaugacgag aauaacaacg cagucagcua cgccacggau     2940

gacgggcaga aucucuccgg caaguucaaa gccgacaagc caggccgcua uuacauucac     3000

cuguauaugu uuaacgggag cuacaugccc uaucggauca auauugaagg uagugugggg     3060

agguga                                                                3066


<210>  806
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  806
augaaguggg ugaccuucau cagccugcuc uuucuguucu ccagugccua cagcguccag       60

aacgagucca aaagguauac ugugaguuac uugaagaccc ugaauuauua cgaccucgua      120

gaucuguugg ugaaaacgga aauugagaac cugcccgacc ucuuucaaua uagcuccgau      180

gcaaaggagu ucuacggcaa uaaaacucgg augagcuuua ucauggacga aauugggcgc      240

agggccccac aguauaccga aaucgaucac aaggguauuc cgacccuggu cgagguggug      300

cgggcgggcu ucuaccuggg guuucauaac aaggagcuca augaaaucaa caaacgcucc      360

uucaaggaga gggucauccc caguauucug gccauccaga aaaauccaaa cuuuaaguug      420

ggcacugaag ugcaggacaa aauuguaagc gcaaccgguc ugcucgccgg gaaugagacg      480

gcacccccag agguggucaa caauuucacu cccauccugc aagauugcau uaagaacauc      540

gaccgguacg cccuggauga cuugaaaucc aaggcgcucu uuaaugugcu ggccgcacca      600

accuaugaua uuacugaaua ccugcgcgcc accaaggaga aaccggaaaa cacccccugg      660

uauggcaaga ucgacggcuu caucaaugag cucaaaaagc uggccuugua cgggaaaauu      720

aacgauaaca auagcuggau cauugacaac gguaucuauc acauugcacc acugggcaag      780

cuccauagua auaacaagau cgggaucgaa acgcugacug aggugaugaa agucuacccc      840

uaucugucca ugcagcacuu gcagagcgcc gaccagauua agaggcauua cgauuccaaa      900

gacgcggagg gcaauaagau cccacucgau aaauucaaga aggaagguaa agagaaguac      960

ugucccaaaa ccuauacuuu ugacgauggg aaggugauua ucaaagccgg cgcacgggua     1020

gaagaggaaa aggugaagcg ccuguacugg gccaguaaag aggucaacag ccaauucuuu     1080

aggguguaug gcauugacaa gccgcuggag gaagggaauc ccgaugacau ccucaccaug     1140

gugaucuaca acuccccaga ggaauauaaa cugaauagcg ucuuguacgg uuaugauacc     1200

aacaauggcg ggauguacau ugagcccgaa ggcacuuucu uuacguacga gcgggaggca     1260

caggaaagua ccuauacucu ggaggaacuc uuccgccacg aguacaccca cuaucugcag     1320

gguagguacg ccgugccagg ccaguggggg cggaccaagc uguaugacaa cgaucgcuug     1380

acuugguacg aggaaggcgg ggccgagcuc uuugcggguu ccacgaggac cagcggcauc     1440

cugccccgga aaaguauugu auccaauauc cauaacacua cccgcaauaa cagguauaag     1500

cugagcgaca ccgugcacag caaauacggg gcauccuucg aauuuuacaa cuaugccugc     1560

auguucaugg acuacaugua uaauaaggau augggcauuc ucaacaagcu gaaugacuug     1620

gccaaaaaca augaugucga cgguuacgau aacuauaucc gggaccugag uagcaauuac     1680

gcacucaacg auaaguauca agaccauaug caggagagga uugauaauua cgaaaaccug     1740

acugugccau uugucgccga cgauuaccug gugcgccacg cguauaaaaa uccgaacgag     1800

aucuacuccg agaucagcga aguggccaag uugaaagacg caaagaguga gguaaagaaa     1860

ucccaguauu ucagcacguu uacccugcgg ggcuccuaca cugggggcgc caguaagggg     1920

aaacucgaag aucaaaaggc aaugaauaaa uucauugacg acagccugaa gaagcucgau     1980

accuauuccu ggagcggcua caaaacucug accgccuacu ucacgaacua uaagguggac     2040

aguuccaaua gggucaccua cgaugugguc uuucacgguu auuugcccaa cgagggggac     2100

agcaaaaacu cccugccaua cggcaagauc aaugguacuu auaaaggcac cgaaaaggag     2160

aaaauuaagu ucaguagcga gggguccuuu gaucccgacg gcaagaucgu gagcuacgaa     2220

ugggauuucg gggacggcaa caaaaguaau gaggaaaacc cagagcauuc cuaugauaag     2280

guggguacuu acaccguaaa acucaaggug acggacgaua aaggggaaag cuccgucagc     2340

accacuaccg ccgagauuaa ggaccugagu gagaauaagc ugcccgugau cuacaugcac     2400

gucccgaaaa gcggcgcauu gaaccagaag gugguguuuu auggcaaagg gacuuacgac     2460

ccagaugguu ccaucgccgg cuaucagugg gacuucgggg auggcaguga cuuuagcucc     2520

gaacagaauc ccagccaugu auacaccaag aaaggugagu auacggucac ccugcgcgug     2580

auggauucca gugggcaaau gagcgaaaag acuaugaaga uuaaaaucac cgaccccgug     2640

uacccaauug gcacugagaa ggagcccaac aauuccaaag aaaccgcgag uggcccaauc     2700

gucccgggga uucccgugag cgguacgauc gagaacaccu ccgaucagga cuauuucuac     2760

uuugauguga ucacuccagg cgaaguaaag auugacauca auaaacucgg guacggcggu     2820

gccaccuggg ucguguauga ugagaacaau aacgcaguga gcuacgccac ugacgauggg     2880

cagaaucuga guggcaaguu caaagccgac aagcccggcc gguauuacau ucaccucuau     2940

auguuuaacg gguccuacau gccauauagg aucaacauug aagguagcgu cggccgcuga     3000


<210>  807
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  807
augaaguggg ugaccuucau cagccugcuc uuucuguucu ccagugccua cagcaugaaa       60

aggaagugcu uguccaaacg gcugaugcuc gcaauuacua uggccaccau cuuuacgguc      120

aacaguacuc ugcccauuua ugcggccgug gacaagaaua acgcaaccgc cgcacgcagg      180

cggcgcaaaa ggguacagaa ugagagcaag cgguacaccg uguccuauuu gaagacucug      240

aacuacuaug aucucgucga ccugcuggug aaaaccgaaa ucgagaaucu cccagaucug      300

uuccaauaca gcuccgacgc caaggaauuu uauggcaaca aaacgcgcau gaguuucauu      360

auggaugaga ucgggaggcg ggcgccgcag uacacugaaa ucgaccacaa ggguauuccc      420

accuuggugg aggucgugcg cgccggcuuu uaccuggggu uccauaauaa agagcucaac      480

gaaaucaaua agaggagcuu uaaagagcgg guaauuccau ccauccuggc aauucagaag      540

aaccccaauu ucaagcuggg cacugaagug caggauaaaa ucgucagcgc caccgguuug      600

cucgccggga acgagaccgc accacccgag guggugaaua acuuuacgcc aauucugcaa      660

gacuguauca agaauaucga ucgcuaugcc cuggacgauc ucaaaaguaa ggcgcuguuc      720

aacgucuugg ccgcaccgac uuacgacauu accgaauauc ugagggccac uaaagagaag      780

cccgaaaaca ccccauggua cggcaagauc gauggcuuca uuaaugagcu caaaaagcug      840

gcacuguaug ggaaaaucaa cgacaauaac uccuggauua ucgacaaugg uaucuaccac      900

auugcccccu ugggcaagcu ccauagcaac aauaaaaucg ggauugaaac ccugacugag      960

gugaugaagg uauauccaua ccuguccaug cagcaccucc agagugccga ucagaucaag     1020

cggcauuacg acagcaaaga ugcggagggc aacaagauuc cccuggacaa auuuaagaaa     1080

gaagguaagg agaaguauug cccgaaaacg uacaccuucg augacgggaa ggugaucauc     1140

aaagcaggcg cccgcgucga agaggaaaag gugaaaaggu uguauugggc cuccaaggag     1200

gugaauagcc aauuuuuccg ggucuacggc auugauaaac cccuggagga agggaaccca     1260

gacgauaucc ucacuauggu gauuuauaau agucccgagg aauacaagcu gaacuccgua     1320

cuguaugguu acgacaccaa uaacggcggg auguacaucg agccagaagg caccuuuuuc     1380

acuuaugagc gcgaggcaca ggaaagcacg uacaccuugg aggaacucuu uaggcacgag     1440

uauacucacu accugcaggg ucgguaugcc gugcccggcc agugggggag gaccaagcug     1500

uacgauaaug accgccucac cugguaugag gaaggcgggg cggagcuguu cgccgguagu     1560

acucggacgu ccggcauuuu gccaaggaaa agcaucguca gcaacauuca uaacaccacu     1620

cgcaauaacc gguacaagcu guccgacacc gugcacagua aauacggggc gagcuuugag     1680

uucuauaauu acgccuguau guuuauggau uauauguaca acaaggacau gggcauccuc     1740

aauaaacuga acgaucuggc aaagaauaac gacgucgaug guuaugacaa uuacaucagg     1800

gauuugucca gcaacuaugc ccugaaugac aaguaccaag aucauaugca ggaacgcauu     1860

gacaacuacg aaaaucucac ugugccguuc guggccgaug acuaucuggu acggcacgca     1920

uacaaaaacc ccaaugagau cuauagugag auuuccgaag uggccaagcu caaagaugca     1980

aagagcgagg ucaaaaaguc ccaguacuuu aguaccuuca cgcugagggg cagcuauacc     2040

gggggcgccu ccaaggggaa auuggaagac caaaaggcaa ugaacaaauu caucgacgau     2100

agccugaaga aacucgacac uuacaguugg uccggcuaca agacccugac ugccuauuuu     2160

accaacuaca aaguggauag cuccaaucgg gucacguaug acgugguguu ccacgguuac     2220

cugccaaacg agggggauag uaagaauagc uugcccuaug gcaagauuaa cgguaccuac     2280

aaaggcacug aaaaggagaa aaucaaguuu uccagcgagg ggaguuucga cccagauggc     2340

aaaaucguau ccuaugaaug ggacuuuggg gauggcaaua agagcaacga ggaaaauccc     2400

gagcauuccu acgacaaggu ggguaccuac acugucaaac ugaaggugac cgaugacaaa     2460

ggggaaagca gugucagcac gaccacugcc gagauuaagg accucuccga gaacaaacug     2520

ccggugaucu auaugcacgu gccaaagagu ggcgcacuca aucagaaggu agucuucuac     2580

ggcaaaggga ccuaugaucc cgacgguagc auugcgggcu accaguggga uuuuggggac     2640

ggcuccgauu ucagcuccga acagaacccc agucaugugu auacuaagaa aggugaguac     2700

accgugacgc ugcgcgucau ggacagcucc gggcaaauga gugaaaagac caugaaaauc     2760

aagauuacug auccagugua ucccaucggc accgagaaag agccaaauaa cagcaaggaa     2820

acugccuccg gcccgaucgu gcccgggauu ccaguaagcg guaccaucga gaauaccagu     2880

gaccaggauu acuuuuacuu cgacgucauu acucccggcg aagugaagau cgauauuaac     2940

aaauuggggu auggcggugc aacgugggug gucuacgacg agaauaacaa cgccgugucc     3000

uaugccaccg augacgggca gaaucugagc ggcaaguuua aagcagacaa gccaggcagg     3060

uacuauaucc accuguacau guucaacggg uccuauaugc ccuaccggau uaauaucgaa     3120

gguagcguag gccgcuga                                                   3138


<210>  808
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  808
augggcaccu ggauccuguu cgccugccuc cugggggcag ccuuugcgau gcccuugcca       60

ccgcaccccg gucauccagg cuacauuaac uucagcuaug aggugcugac uccccucaag      120

ugguaccagu ccaucaggcc acccuaucca aguuacgggu augaaccgau gggcgguugg      180

cugcaccauc aaauuauccc cgucuugagc cagcagcacc cacccaccca uacgcugcag      240

ccacaccacc auauucccgu gguaccggcc caacagcccg ugaucccaca gcagcccaug      300

augccagucc ccgggcaaca cuccaugacu ccaauccagc aucaccagcc gaaucugccc      360

ccacccgcac agcaaccaua ccagccccag ccggugcaac cacagcccca ccagcccaug      420

cagccacaac ccccagugca uccgaugcag ccccucccac cccagccacc ccugccgcca      480

auguuuccca ugcagccacu gcccccgaug cuccccgacu ugacccugga ggccuggcca      540

aguaccgaua aaacuaagcg ggaagagguc gacuga                                576


<210>  809
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  809
augccccugc caccgcaccc cggccaucca ggguacauca acuucagcua ugaggugcuc       60

accccacuga agugguacca guccauuagg ccacccuauc ccaguuacgg uuaugaaccg      120

augggcgggu gguga                                                       135


<210>  810
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  810
augccccugc caccgcaccc cggccaucca ggguacauca acuucagcua ugaggugcuc       60

acuccccuga agugguacca guccauuagg ccacccccaa uguugccgga ccugacccuc      120

gaagccuggc ccaguaccga uaaaacgaag cgggaggaag ucgacuga                   168


<210>  811
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  811
auggccguga uggcacccag gacccugguc cuccuguuga gcggcgcccu ggcgcucacu       60

cagaccuggg ccaugccacu gccgccccac ccagggcauc ccgguuacau caacuucucc      120

uaugaggugu ugacgccacu gaagugguac caaaguauuc ggcccccaua uccgagcuac      180

ggcuaugaac ccaugggcgg gugguga                                          207


<210>  812
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  812
auggccguga uggcacccag gacccugguc cuccuguuga gcggcgcccu ggcgcucacu       60

cagaccuggg ccaugccacu gccgccccac ccagggcauc ccgguuacau caacuucucc      120

uaugaggugu ugacgccacu gaagugguac caaaguauuc ggcccccacc gaugcucccc      180

gaccugacuc uggaagcaug gccaagcacc gauaaaacca agcgcgagga aguagacuga      240


<210>  813
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  813
augggcaccu ggauccuguu cgccugccuc gugggggcag ccuuugcgau gccccugcca       60

ccgcaccccg gucauccagg cuacauuaac uucagcuaug aggucuugac uccccugaag      120

ugguaccagu ccaugaucag gccacccuau aguagcuacg gguaugaacc aaugggcggu      180

uggcuccacc aucaaauuau cccgguggua ucccagcagc acccccugac ccauacguug      240

cagagucacc accauauucc aguggucccc gcccaacagc cacgggugcg ccagcaggca      300

cugaugcccg ugccggggca acagagcaug acucccaccc agcaccauca gccaaaucuc      360

ccccugccag cccaacagcc cuuucagcca caaccggucc agccccagcc acaccagccc      420

augcaaccac agcccccggu gcagccaaug cagccccugc ucccccaacc accccugcca      480

ccgauguucc ccuugaggcc acugccccca auccuccccg accugcaccu ggaggcaugg      540

ccggccaccg auaaaacuaa gcaggaagag guagacuga                             579


<210>  814
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  814
augccccugc caccgcaccc cggccaucca ggguacauca acuucagcua ugaggugcuc       60

accccacuga agugguacca guccaugauu aggccacccu auaguagcua cgguuaugaa      120

cccaugggcg ggugguga                                                    138


<210>  815
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  815
augccccugc caccgcaccc cggccaucca ggguacauca acuucagcua ugaggugcuc       60

acuccccuga agugguacca guccaugauu aggccacccc caaucuugcc ggaccugcac      120

cucgaagccu ggcccgcaac cgauaaaacc aagcaagagg aagucgacug a               171


<210>  816
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  816
auggccguga uggcacccag gacccugguc cuccuguuga gcggcgcccu ggcgcucacu       60

cagaccuggg ccaugccacu gccgccccac ccagggcauc ccgguuacau caacuucucc      120

uaugaggugu ugacgccacu gaagugguac caaaguauga uucggccccc auauagcucc      180

uacggcuaug aaccgauggg cgggugguga                                       210


<210>  817
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  817
auggccguga uggcacccag gacccugguc cuccuguuga gcggcgcccu ggcgcucacu       60

cagaccuggg ccaugccacu gccgccccac ccagggcauc ccgguuacau caacuucucc      120

uaugaggugu ugacgccacu gaagugguac caaaguauga uucggccccc accgauccuc      180

cccgaccugc accuggaagc auggccagcc acugauaaaa ccaagcagga ggaaguagac      240

uga                                                                    243


<210>  818
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  818
augggcaccu ggauccuguu cgccugccuc cugggggcag ccuuuagcau gcccuugcca       60

ccgcaccccg gucauccagg cuacauuaac uucuccuaug aggugcugac uccccucaag      120

ugguaccaga auaugaucag gcacccauau accaguuacg gguaugaacc caugggcggu      180

uggcugcauc accaaauuau cccagucgug agccagcaga cgccgcaguc ccaugcguug      240

caaccccacc accauauucc aaugguaccc gcccagcagc cagggauccc ccagcaaccg      300

augaugcccc ugccaggcca gcacaguaug acucccaccc agcaucacca gccaaaccuc      360

ccccugccag cacaacagcc guuucagccc caaccagugc agccccagcc acaccagccc      420

cugcaaccgc agagcccaau gcaucccauc cagccccucc ugccacagcc cccauugccg      480

cccauguucu ccaugcaaag ccugcuccca gaccugcccc uggaggccug gccagcaacc      540

gauaaaacua agcgggaaga ggucgacuga                                       570


<210>  819
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  819
augccccugc caccgcaccc cggccaucca ggguacauca acuucagcua ugaggugcuc       60

acuccccuga agugguacca gaauaugauu aggcacccau auaccuccua cgguuaugaa      120

cccaugggcg ggugguga                                                    138


<210>  820
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  820
augccccugc caccgcaccc cggccaucca ggguacauca acuucagcua ugaggugcuc       60

acuccccuga agugguacca gaauaugauu aggcacccau ccuugcugcc cgaccuccca      120

cuggaagccu ggccggcaac cgauaaaacc aagcgggagg aagucgacug a               171


<210>  821
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  821
auggccguga uggcacccag gacucugguc cuccuguuga gcggcgcccu ggcgcucacu       60

cagaccuggg ccaugccacu gccgccccac ccagggcauc ccgguuacau caacuucucc      120

uaugaggugu ugacgccacu gaagugguac caaaauauga uucggcaccc cuauaccagu      180

uacggcuaug aaccaauggg cgggugguga                                       210


<210>  822
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  822
auggccguga uggcacccag gacccugguc cuccuguuga gcggcgcccu ggcgcucacu       60

cagaccuggg ccaugccacu gccgccccac ccagggcauc ccgguuacau caacuucucc      120

uaugaggugu ugacgccacu gaagugguac caaaauauga uucggcaccc cagucuccug      180

ccagaccugc cgcucgaagc auggcccgcc acugauaaaa ccaagcgcga ggaaguagac      240

uga                                                                    243


<210>  823
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  823
augggcaccu ggauccuguu cgccugccuc cugggggcag ccuuuagcau gcccuugcca       60

ccgcaccccg gucauccagg cuacauuaac uucuccuaua ucaggcaccc cuacaccagu      120

uauggguacg agccaauggg cgguuggcug caucaccaga uuauccccgu ggucagccaa      180

cagacuccac agucccaugc gcuccagccg caccaccaua uucccauggu gccagcccaa      240

cagcccggga ucccacagca gcccaugaug ccgcugcccg gccaacacag uaugacgcca      300

acucagcauc accagcccaa uuugccacug cccgcacagc aaccauuuca gccgcagccc      360

guacaaccac agccccacca gccacuccag ccccaaagcc cgaugcaucc aauccagccc      420

cugcugcccc agccaccccu cccaccgaug uucuccaugc agagccuguu gcccgaccug      480

ccacucgaag ccuggcccgc aaccgauaag accaaacggg aggaagugga cuga            534


<210>  824
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  824
augggcaccu ggaucuucuu ugccugccug cucggggcaa gccuggccau gcccuugcca       60

ccgcaccccg gucauccagg cuacauuaac uucuccuaug aggugcugac uccccucaag      120

ugguaccaga auaugaucag gcacccauau accaguuacg gguaugaacc caugggcggu      180

uggcugcauc accaaauuau cccagucgug agccagcaga cgccgcaguc ccaugcguug      240

caaccccacc accauauucc aaugguaccc gcccagcagc cagggauccc ccagcaaccg      300

augaugcccc ugccaggcca gcacaguaug acucccaccc agcaucacca gccaaaccuc      360

ccccugccag cacaacagcc guuucagccc caaccagugc agccccagcc acaccagccc      420

cugcaaccgc agagcccaau gcaucccauc cagccccucc ugccacagcc cccauugccg      480

cccauguucu ccaugcaaag ccugcuccca gaccugcccc uggaggccug gccagcaacc      540

gauaaaacua agcgggaaga ggucgacuga                                       570


<210>  825
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  825
augggcaccu ggauccuguu cgccugccuc cugggggcag ccuuuagcau gcccuugcca       60

ccgcaccccg gucauccagg cuacauuaac uucuccuaug aggugcugac uccccucaag      120

ugguaccaga auaugaucag gcacccaagu cuguugcccg accugccacu cgaagcgugg      180

ccggccaccg auaaaacgaa gcgggaggaa gucgacuga                             219


<210>  826
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  826
augggcaccu ggauccuguu cgccugccuc cugggggcag ccuuuagcau gcccuugcca       60

ccgcaccccg gucauccagg cuacauuaac uucuccuaug aggaccugua ccucgaagcg      120

aucaggauug aucggacugc cuuugugcug acccccuuga agugguauca gaauaugauc      180

cgccacccau acacgaguua uggguacgag cccaugggcg guuggcugca ucaccaaauu      240

aucccagucg ugagccagca gacuccgcag ucccaugcac uccaacccca ccaccauauc      300

ccaaugguac ccgcccagca gccagggauu ccccagcaac cgaugaugcc ccugccaggc      360

cagcacagua ugacccccac ccagcaucac cagccaaacc ugccccuccc agcacaacag      420

ccguuccagc cccaaccagu gcagccccag ccacaccagc cccugcaacc gcagagccca      480

augcauccca uccagcccuu gcugccacag cccccacucc cgcccauguu uuccaugcaa      540

agccugcugc cagacuugcc ccucgaagcc uggccagcga cugauaaaac caagagggag      600

gaagucgacu ga                                                          612


<210>  827
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  827
augggcaccu ggauccuguu cgccugccuc cugggggcag ccuuuagcau gcccuugcca       60

ccgcaccccg gucauccagg cuacauuaac uucuccuaug aggugcugac uccccucaag      120

ugguaccaga auaugaucag gcacccaacg ccccaaaguc augcgcugca gccacaccau      180

cacauuccga ugguccccgc ccagcagcca gggauccccc aacagccaau gaugcccuug      240

ccgggccagc acagcaugac ccccacucag caucaccaac caaaccugcc ccucccagca      300

cagcagcccu uucagccaca accggugcag ccccagccac aucaaccccu gcagccacag      360

ucccccaugc acccgauuca gccacugcuc ccccaacccc cacugccccc aauguucagu      420

augcagagcu ugcugccgga ccucccccug gaagccuggc cagcaaccga uaaaaccaag      480

cgggaggaag uagacuga                                                    498


<210>  828
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  828
augccccugc caccgcaccc cggccaucca ggguacauca acuucagcua ugaggugcuc       60

acuccccuga agugguacca gaauaugauu aggcacccau auaccuccua cgguuaugaa      120

cccaugggcg ggugguugca ucaccaaauc auuccagucg ugagucagca gaccccgcag      180

agccaugccc ugcaacccca ccaccauauc ccaaugguac ccgcacagca gccaggcauu      240

ccccagcaac cgaugaugcc ccucccaggu cagcacucca ugacgcccac ucagcaucac      300

cagccaaacc ugcccuugcc agcccaacag ccguuucagc cccaaccagu gcagccccag      360

ccacaccagc cccugcaacc gcagagucca augcauccca uccagccccu ccugccacag      420

cccccacugc cgcccauguu cagcaugcaa ucccuccugc cagacuugcc ccuggaggcg      480

uggccagcca ccgauaaaac caagcgggaa gaggucgacu ga                         522


<210>  829
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  829
augcccggcg uggccaggcu gccacuccug uuggggcugc uccuguugcc gcggcccggu       60

cgcccacugg accucgcaga uuacaccuau gaccuggccg aggaagauga cagcgagccc      120

cugaacuaca aggauccaug caaagcggcc gcauuccucg gcgacaucgc ccuggaugaa      180

gaggacuuga gggcauuuca gguccaacag gccguggauc ugcggcgcca cacugcgagg      240

aaguccagua uuaaagccgc aguacccggg aauaccagca cgccauccug ucagaguacu      300

aacggccagc cgcaacgggg ugccugcggg cgcuggaggg gccggagccg cuccaggcgg      360

gccgcaacca gccgccccga aagggugugg ccagacggcg ucauccccuu cgugauuggg      420

gguaauuuua ccggcuccca gcgggccgug uuccgccagg cgaugaggca uugggagaag      480

cacacuugug ucaccuuucu cgagcggacg gaugaagaca guuauaucgu guucacuuac      540

cgcccaugcg gguguugcag cuauguaggc aggcggggug ggggccccca ggccauuucc      600

aucggcaaaa acugugauaa guuugggauc gugguccaug agcuggguca cguggugggc      660

uucuggcaug aacacaccag gccggaccgc gaccggcacg ucagcauugu gagggagaau      720

auccaacccg ggcaggagua caacuuucug aagauggaac cacaggaggu agaaaguuug      780

ggcgagacuu augauuucga cuccauuaug cauuacgcac gcaauaccuu uagccggggu      840

aucuuccucg auaccauugu gcccaaauac gaagucaacg gcgugaagcc acccaucggg      900

cagaggacgc gccuguccaa aggcgacauu gcccaagcac ggaagcugua uaaaugccca      960

gccugugggg agacucucca ggauaguacc gguaauuuca gcuccccgga guaccccaac     1020

ggcuauagcg cccacaugca uugcgugugg aggaucagug ucacuccagg ggaaaagauc     1080

auucugaauu uuaccuccuu ggaccuguac cggagccgcc ucugcuggua ugauuacgug     1140

gagguaaggg acggcuucug gcggaaagcg ccccugcgcg guagguuuug uggcaguaag     1200

cugccagaac ccaucguguc caccgauagc cgguuguggg ucgaguuccg cagcuccagu     1260

aacugggugg ggaagggcuu uuucgcaguc uaugaagcca uuugcggggg cgacgugaaa     1320

aaggauuacg gucacaucca gagcccgaau uacccagacg acuauaggcc cuccaaagug     1380

uguauuuggc ggauccaagu aagcgagggg uuucacgugg gccucacuuu ccagaguuuu     1440

gagaucgaaa ggcaugauuc cugcgccuac gacuaucugg agguccgcga uggucacagc     1500

gaauccagua cgcugauugg ccgguacugu ggguaugaga agcccgacga uaucaaaagc     1560

accuccagca ggcucuggcu gaaguucgug agugacggcu ccauuaacaa ggcaggguuu     1620

gccgucaauu ucuuuaaaga aguggaugag ugcagccgcc caaaccgggg cgguugugag     1680

cagaggugcu ugaacacucu gggguccuac aaguguaguu gcgaccccgg cuaugaacuc     1740

gcgccagaua aacgccggug cgaggccgca uguggcgggu uccugaccaa gcugaauggu     1800

agcaucaccu ccccgggcug gcccaaagaa uacccaccca acaagaauug cauuuggcag     1860

uugguggccc caacucaaua caggaucagc cuccaguucg acuuuuucga gacggagggg     1920

aacgauguau guaaguauga cuuuguggaa guccgcagug gccugaccgc agauuccaaa     1980

cugcauggua aguucugcgg gagcgagaaa cccgaaguga ucacuuccca guacaauaac     2040

augcgggucg aguuuaagag cgacaauacc gugaguaaaa agggcuucaa ggcccacuuu     2100

uucagcgaca aagaugaaug uuccaaggac aacggcgggu gccagcaaga uugugugaau     2160

accuuuggua guuaugagug ccaguguagg agcggcuucg uacuccauga caacaaacac     2220

gauugcaagg aggccgggug ugaccacaaa gucacuucca cgagcggcac cauuacuucc     2280

ccgaauuggc cagauaagua ccccaguaaa aaggaaugca ccugggcaau cagcuccacu     2340

ccaggucauc gcgugaagcu gaccuuuaug gagauggaca uugaaaguca gcccgagugc     2400

gccuaugauc acuuggaagu guucgacggg cgggaugcga aagccccggu ccugggcagg     2460

uucuguggca gcaagaaacc cgagccagug cucgcaacgg ggucccgcau guuucugcgg     2520

uucuacagcg acaacagugu gcagaggaag gguuuucaag ccucccaugc caccgagugc     2580

ggcgggcagg uacgcgcaga cgucaaaacu aaggaucugu auagccacgc gcaguucggc     2640

gacaauaacu accccggugg gguggauugu gaauggguga ucgucgccga ggaaggcuac     2700

ggcguggagu ugguauuuca gaccuucgaa guggaggagg aaacugacug cggguaugau     2760

uacauggagc uguuugacgg uuaugauucc accgcaccaa ggcucggccg guacuguggg     2820

agcggucccc cagaagaggu cuauagugcc ggcgacuccg ugcuggugaa guuccacagc     2880

gaugacacga uuaccaaaaa gggcuuucau cucagguaca ccaguacuaa auuccaagau     2940

acucugcacu cccgcaagug a                                               2961


<210>  830
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  830
augguggccg gcaccaggug ccugcucgca cuguugcugc cccagguccu ccuggguggg       60

gccgcgggcu uggugccaga gcuggggcgg cgcaaguucg ccgcagccag cuccggcagg      120

ccgaguagcc aacccuccga cgaaguacuc agugaguuug aacugcggcu gcucagcaug      180

uucggucuga aacagcgccc aacucccucc agggaugcag uggucccacc cuacauguug      240

gaccuguauc ggcgccacag cgggcagcca ggcuccccgg cccccgauca uaggcucgag      300

cgggcggcca gucgcgcaaa caccgugagg agcuuucacc augaagaguc ccuggaggaa      360

cugccagaga cgagcggcaa gacuacccgg cgcuucuuuu ucaauuugag uuccaucccc      420

accgaagagu uuauuacuag cgccgagcuc cagguguuca gggaacaaau gcaggacgcc      480

cuggggaaca auuccaguuu ucaccaucgg aucaacauuu acgagaucau uaaaccagca      540

accgccaaua gcaaguuccc cgucacgcgc cugcucgaua cuaggcuggu gaaccagaau      600

gcgucccggu gggaauccuu ugacguaacc ccggccguga ugcgcuggac ugcacagggu      660

cacgccaacc acggcuucgu cguggaggug gcacauuugg aagagaaaca aggggucagu      720

aagaggcacg ugcggaucuc caggagccug caucaggaug agcacaguug gucccagauc      780

cgcccccucc ugguaaccuu cggccacgac gguaaggggc auccacugca caaacgggaa      840

aagaggcagg ccaaacauaa gcaacgcaaa cggcucaaga gcagcuguaa aaggcacccc      900

uuguaugugg auuuuuccga cgucggcugg aaugauugga uuguggcccc acccggcuac      960

caugcguucu auugccacgg ggagugucca uuuccgcugg cagaccaccu gaacaguacc     1020

aaucaugcca ucgugcagac gcucgucaac agcgugaaua gcaagauucc caaggccugc     1080

uguguaccaa cugaacugag cgcaaucagu auguuguacc uggaugagaa cgaaaaagug     1140

guccucaaga auuaucagga cauggugguc gaggguugcg gcugucgcug a              1191


<210>  831
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  831
augauccccg gcaacaggau gcugauggug guccuccugu gccagguguu gcucgggggu       60

gccagccacg caucccugau uccagagacc ggcaagaaaa agguagccga aauccaaggg      120

caugcgggcg gucggcgcag ugggcagagc cacgagcugu ugagggacuu cgaagccacu      180

cugcuccaga uguuuggccu gcggcgcagg ccgcagcccu ccaaaagugc agugauucca      240

gauuacaugc gggaccugua ucgccuccaa agcggcgagg aagaggagga acagauccau      300

uccaccgggc uggaguaccc cgaaaggcca gccagccggg caaauacggu ccgcuccuuc      360

caccaugagg agcacuugga aaacauuccc gguaccagug agaauagcgc cuuuagguuc      420

cuguuuaacc ucuccagcau cccagaaaau gaggugauca guuccgcgga acugcggcug      480

uuccgcgaac agguggauca gggcccggac ugggagaggg gguuucaccg gauuaacauc      540

uaugagguca ugaagccccc agccgaggug guacccggcc auuugauuac ucgccuccug      600

gauaccaggc uggugcacca uaaugucacu cggugggaaa ccuucgacgu gagcccagca      660

gugcuccgcu ggacgaggga gaaacaaccc aacuacgguc uggccaucga agucacucac      720

uugcaccaga cccggacuca ucaggggcag cacgugagga uuucccgcag ucugccgcaa      780

ggcagcggca auugggccca gcuccggccc cugcugguaa ccuuugggca ugaugguagg      840

ggccacgcau ugacccgccg gaggcgcgcc aagcgguccc caaagcauca cagccagagg      900

gcgcggaaaa agaacaaaaa uugucgcagg cacagucucu auguggacuu cuccgauguc      960

ggguggaacg acuggaucgu ggcaccccca ggcuaccaag ccuuuuauug ccauggugau     1020

ugucccuucc cacuggccga ccaccugaau agcacgaacc augcaauugu gcagacucuc     1080

gucaauagug ugaacuccag caucccgaag gccugcugug uacccaccga gcugagcgcc     1140

aucuccaugu uguaccugga ugaguacgac aaaguggucc ucaagaacua ucaggaaaug     1200

guggucgagg gcugcgggug ucgguga                                         1227


<210>  832
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  832
augcccggcc uggggaggcg ggcccagugg cucugcuggu gguggggucu guuguguagc       60

ugcuguggcc caccgccccu gcgcccaccc cucccagcag ccgcggccgc agccgcaggg      120

ggccaacugu ugggugacgg gggcuccccc ggcaggaccg agcagccacc gcccagucca      180

cagagcucca guggguuccu guaccggcgc cucaagacuc aggagaaaag ggaaaugcaa      240

aaggaaaucc ugagcgugcu gggucucccc caccggccac gcccccugca uggcuugcag      300

cagccgcagc ccccagcccu gaggcaacag gaggaacagc agcaacagca gcaacucccc      360

cgcggggagc cacccccagg ccggcugaaa uccgcgccgc uguuuauguu ggaucucuau      420

aacgcccuga gcgcagacaa ugaugaggac ggugccuccg aaggggagag gcagcagagu      480

uggccccacg aagccgcaag cuccagccag cggcgccaac cacccccagg cgccgcgcau      540

ccccugaaca ggaagagucu ccuggccccg ggcuccggga gcgguggcgc auccccauug      600

accagugccc aggauagcgc auuccugaau gacgccgaua uggucauguc cuuugugaac      660

cucguagagu acgacaaaga guucagcccc cggcagcgcc accauaagga auuuaaguuc      720

aaucugaguc agauucccga gggggaagug gucacggccg cggaguuuag gaucuauaaa      780

gauugcguga ugggcuccuu caagaaccaa acuuuucuga uuagcaucua ccagguguug      840

caggaacacc agcaccggga cagugaucuc uuccugcugg acacccgcgu cgugugggca      900

uccgaggagg guuggcucga auuugauauu accgccacua gcaaucugug gguagugacc      960

ccacaacaua acaugggcuu gcagcugagc gucgugacga gggacggggu gcacguccau     1020

ccccgggccg caggccucgu ggggagggac gguccauaug auaaacagcc guucauggua     1080

gccuucuuua agguguccga gguccacgug cgcacuaccc ggagugcgag cuccaggcgc     1140

cggcagcaaa gcaggaaucg caguacucag ucccaggacg uggcccgggu cagcuccgca     1200

agugauuaca acagcuccga acugaaaacc gccuguagga agcacgagcu guaugugagc     1260

uuccaagacu ugggcuggca ggauuggauc aucgcaccca aaggguacgc cgccaauuac     1320

ugcgacggcg aauguaguuu uccacucaac gcacauauga augccaccaa ccacgcgauu     1380

guacagacgc uggugcaucu gaugaauccc gaguaugucc caaagcccug cugugccccg     1440

acuaagcuca acgcaaucuc cgugcuguac uucgaugaca acagcaaugu cauuuugaaa     1500

aaguaucgga acaugguggu gcgcgccugc gguugccacu ga                        1542


<210>  833
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  833
augcacguga ggagccugcg ggccgcagcg ccccauuccu ucgucgcccu cugggcccca       60

cuguuuuugc ugcgcagugc acucgccgac uucagccugg auaacgaggu gcacuccagu      120

uuuauccaua ggcgguugcg cagccaggaa aggcgggaga ugcaacgcga aauucugucc      180

auccucggcc ugccgcacag gccccggcca caucugcagg ggaagcacaa uagcgcaccc      240

auguucaugc ucgaccugua caacgccaug gcgguagagg aagguggcgg gccaggcggu      300

cagggguuuu ccuaucccua caaagccgug uucaguaccc agggcccacc guuggcaagc      360

cugcaagauu cccacuuucu cacugacgcc gauaugguca ugagcuucgu gaaucuggug      420

gagcaugaca aggaguuuuu ccacccccgc uaucaucaca gggaauuucg guucgaucug      480

aguaaaauuc cagagggcga agccgucacc gcagccgagu uccgcaucua caaggacuau      540

auuagggagc gguuugauaa cgaaacguuc cgcaucuccg uguaccaggu auugcaggag      600

caccucggga gggaaagcga ccuguuucug cucgauuccc ggacucugug ggcgagugag      660

gaagguuggu ugguguucga caucaccgcc accagcaauc auugggucgu gaacccccgc      720

cacaaucugg gccuccagcu guccguggag acucuggaug ggcaaagcau uaacccaaaa      780

uuggcaggcc ucaucgguag gcaugggccc cagaauaagc agccguuuau ggucgccuuc      840

uuuaaggcaa ccgaggugca cuuccggagu auuaggucca cgggcagcaa acagcgcagu      900

caaaaccggu ccaagacucc caaaaaucag gaagcccuga ggauggccaa cguagcggag      960

aauagcagcu ccgaccagcg ccaagcaugc aagaaacaug aacuguaugu gaguuuucgg     1020

gaccucggcu ggcaggauug gaucauugcc ccagaggggu acgccgcaua cuauugugaa     1080

ggugagugcg ccuucccccu gaacagcuac augaaugcga ccaaccacgc caucguccag     1140

acuuuggugc acuuuauuaa cccagagacc gugcccaagc cauguugcgc accgacccag     1200

cugaaugcca ucuccguccu cuauuucgac gauagcagua acgugauccu gaaaaaguac     1260

aggaauaugg uagugcgcgc auguggcugc cauuga                               1296


<210>  834
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  834
augaaggcca gcgcagcccu gcucugccug uugcugaccg cggccgcauu caguccccag       60

ggccucgccc aaccaguggg gaucaacacu uccaccacgu guugcuacag guuuauuaau      120

aaaaagaucc cgaaacagcg gcuggagagc uaucgcagga cuaccuccag ucacuguccc      180

cgggaagcag ucauuuucaa gaccaaauug gacaaggaga ucugcgccga uccaacucag      240

aagugggugc aggacuuuau gaaacaucug gauaagaaaa cccaaacgcc caagcucuga      300


<210>  835
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  835
augcugcuca cccugaucau uuugcugccc guggucagca aguucuccuu ugugagucuc       60

agcgccccac agcacugguc cugcccggag ggcacucugg cagggaacgg uaauaguacc      120

uguguaggcc ccgccccauu cuugaucuuu agccauggga acuccauuuu caggaucgac      180

acggaaggca cuaauuacga gcaacuggug gucgacgcgg gugugagcgu gauuauggac      240

uuucacuaua acgaaaaacg gaucuacugg gucgaucucg agcgccagcu gcugcagagg      300

guguuccuca augggucccg gcaggaacgc guaugcaaca ucgagaagaa ugugaguggc      360

auggccauua acuggaucaa ugaggaaguc auuuggagca accaacagga gggcaucauu      420

accgugaccg acaugaaagg gaauaacucc cauauccugu ugagcgcacu gaaguauccc      480

gccaaugugg cagucgaucc aguggaaagg uuuauuuucu ggaguuccga gguagccggu      540

agccucuacc gggcggaccu ggauggcgug ggggucaaag cccuguugga gacuuccgaa      600

aagaucaccg cagugagucu cgacgugcug gauaagcgcc uguuuuggau ccaguauaac      660

agggagggca gcaauucccu cauuuguagc ugcgacuacg auggugggag uguccacauc      720

uccaaacauc ccacgcagca caaccuguuc gccaugagcu uguuuggcga ccggauuuuc      780

uauaguacuu ggaagaugaa aaccaucugg auugccaaca agcacacugg caaagauaug      840

gugcgcauca aucugcauuc cagcuucgua ccacucgggg aacugaaggu gguccacccg      900

cuggcacaac ccaaagccga ggacgacacc ugggaaccag agcagaaguu guguaagcuc      960

aggaaaggua acugcagcuc caccgugugu ggccaggauc ugcagaguca ucugugcaug     1020

ugugcggagg gguacgcccu cagccgggac cgcaaguacu gcgaagaugu caaugagugc     1080

gcauuuugga accacggcug uacgcugggu ugcaaaaaua cucccggcuc cuauuacugu     1140

accugcccag ugggguucgu guugcugccc gacggcaaga ggugucacca acucguaagc     1200

ugcccgcgga acgugaguga auguucccau gauugcgucc ugacuagcga ggggccccug     1260

uguuuuugcc cagaagguuc cguguuggag cgcgacggca aaaccugcag uggguguagc     1320

ucccccgaua auggcgguug cagccagcuc ugugucccac ugagucccgu guccugggag     1380

ugcgacuguu ucccaggcua ugaucugcag cucgacgaaa agagcugcgc cgcauccggg     1440

ccgcaacccu uucuguuguu cgccaacagu caggauauca ggcacaugca uuuugacggc     1500

accgacuacg ggacucugcu cagccagcag augggcaugg uguaugcccu ggaucacgac     1560

ccaguagaga auaagauuua cuucgcgcau acggcacuga aauggaucga acgggccaac     1620

auggaugguu cccaacgcga gagguugauu gaagaggggg uggacguccc cgagggccug     1680

gccguggauu ggaucggucg gagguuuuau uggaccgacc gcggcaagag ccucauuggg     1740

cggagugauc ugaauggcaa aagguccaag aucaucacua aagaaaacau uagccagcca     1800

cgcgggaucg caguccaccc cauggccaag cggcuguucu ggaccgacac cggcauuaau     1860

ccgaggaucg aguccagcag ucuccagggu uuggggcgcc uggugauugc gagcuccgau     1920

cucaucuggc caaguggcau uacuaucgac uuucugacgg auaagcugua cuggugugac     1980

gccaaacaga gcgugaucga aauggcaaac uuggauggcu ccaagcggag gcggcugacc     2040

caaaaugacg uagggcaccc cuucgccguc gcaguguuug aggacuacgu gugguucagc     2100

gauugggcca ugcccuccgu caugcgcgug aacaaaagga cugguaagga ccgggugcgc     2160

cuccagggca guaugcugaa accaagcucc cucguagucg ugcauccccu ggccaagcca     2220

ggggcagauc cgugcuugua ucagaacggc gguugugagc acauuugcaa gaaaaggcug     2280

gggaccgccu gguguaguug ccgggaaggc uucaugaagg cgagcgacgg caaaaccugc     2340

cuggcccucg augggcauca gcuguuggcc gguggcgagg uggaccugaa gaaucaaguc     2400

acuccccucg auauccuguc caaaacgcgc gugagcgaag acaacauuac cgagagucag     2460

cacaugcucg uagcagaaau cauggugucc gaucaggacg auugugcccc agucgggugc     2520

agcauguacg caagguguau uuccgagggc gaggacgcga cuugccagug ucugaagggu     2580

uuugccgggg acggcaaauu gugcagcgau aucgacgaau gugagauggg cgugcccgug     2640

ugcccacccg caaguuccaa guguaucaau accgaagggg guuaugucug ccggugcagc     2700

gagggcuacc aaggggaugg cauucacugu cuggacaucg augaaugcca gcugggugag     2760

cauaguugug gggagaacgc cuccugcacu aauaccgaag gcggcuauac guguaugugc     2820

gccgggaggc ucagcgagcc gggucugauu uguccagacu ccacuccccc accccacuug     2880

cgcgaagaug accaucacua cagcgugcgg aacagugaua gcgagugccc gcugucccau     2940

gacggcuauu gucuccacga ugggguaugc auguacaucg aagcacugga caaguacgcc     3000

ugcaauugug uggucggcua uauuggugag aggugccagu accgcgaucu gaaauggugg     3060

gagcuccggc acgcgggcca ugggcaacag cagaagguga ucguggucgc cgugugugua     3120

gugguccugg ugauguugcu gcuccugagu uuguggggcg cacacuauua caggacccag     3180

aaacugcuca gcaagaaccc caaaaaucca uaugaagagu ccagccgcga cgugcggucc     3240

aggcgccccg ccgacaccga agaugggaug aguagcugcc cacaacccug guucgucgug     3300

aucaaggagc aucaggaccu gaagaacggu ggccagccag uagccgggga ggauggccag     3360

gcagccgacg guuccaugca accgacuagc uggcggcagg aaccccagcu guguggcaug     3420

gggaccgagc agggcugcug gauuccagug aguuccgaua aagggagcug uccccaaguc     3480

auggaaaggu ccuuucacau gccaaguuac gguacgcaga cccucgaggg cgggguggaa     3540

aagccccaca gccuguuguc cgcgaauccg cuguggcagc aacgcgcccu cgauccccca     3600

caucagaugg agcugacuca guga                                            3624


<210>  836
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  836
augaccgccg gcaggcggau ggagaugcug ugcgcagggc gcgugcccgc ccuccuguug       60

ugccuggguu uccaccuccu gcaggcgguc uugagcacua ccgugauccc auccugcauu      120

ccgggcgaaa guagcgacaa cuguacggcc cugguacaaa cugaggauaa ucccagggug      180

gcacaggucu ccaucaccaa gugcaguagc gacaugaacg gguacugucu ccauggccag      240

ugcauuuauc ugguggauau gucccagaau uacugucggu gcgaaguggg uuauaccggg      300

guccgcugug agcacuuuuu ccugacugug caucaaccac ucagcaaaga auacguagcc      360

cugaccguga ucuugauuau ccuguuucuc aucacggucg ugggcuccac uuauuacuuc      420

uguagguggu aucggaaccg caagaguaaa gagcccaaga aagaguacga aagggugacc      480

agcggcgacc cagagcugcc ccaggucuga                                       510


<210>  837
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  837
auggccgagg gcgaaaucac cacuuucacc gcacugacgg agaaguuuaa ccugccccca       60

gggaauuaca aaaagccgaa acucuuguau ugcagcaacg guggccacuu ccugaggauu      120

cuccccgacg ggacugugga uggcacccgg gaccgcuccg aucagcauau ccaacugcag      180

uugagugccg aaagcgucgg ugagguguac auuaagucca ccgaaacugg gcaguaucug      240

gcgauggaca ccgauggccu ccuguacggc agucagacgc caaaugagga gugucuguuu      300

cucgaaaggc uggaggaaaa ccacuauaau acuuacauca gcaaaaagca ugccgagaag      360

aacugguucg uaggguugaa aaagaauggu uccugcaaac ggggcccccg cacccacuau      420

gggcaaaagg caauucuguu ucucccacug cccgugagcu ccgacuga                   468


<210>  838
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  838
auggugggcg ucgggggugg cgacguggag gauguaaccc ccaggccagg gggcugccag       60

aucagcgguc gcggggcccg gggcuguaac ggcauuccgg gggcagccgc gugggaagcc      120

gcacugccca ggcggcgccc aaggcggcac cccuccguga auccacgcag uagggccgca      180

gguagccccc ggacucgcgg caggcggacc gaggaacgcc cauccgggag uaggcucggc      240

gaccgggguc gcgggagggc ccugccgggc ggccgguugg gugggcgcgg cagggggcgg      300

gcgcccgaga gggucggcgg ucgcggccgg gggaggggca cggccgcacc acgcgccgcc      360

cccgcagccc gggggagcag gccagguccc gcgggcacua uggccgcagg guccaucacc      420

acccugccgg cccuccccga agauggcggu agcggcgcau ucccacccgg gcauuuuaag      480

gacccaaaac gccuguacug caagaacggc ggguucuuuu ugcggauuca ccccgauggc      540

aggguggacg gugugcggga gaaauccgau ccacauauca agcugcaacu ccaggccgag      600

gaacgcgggg ucgugaguau uaaaggcgua ugugccaaua gguaucuggc gaugaaggag      660

gacggucggc ugcucgcaag caagugcgug acugaugaau guuucuuuuu cgagcgccug      720

gaguccaaca auuacaacac cuauaggagc cggaaauaca cgaguuggua ugucgccuug      780

aagcgcacug gccaguacaa acuggggucc aagaccggcc cggggcagaa agccauccuc      840

uuucugccca ugagcgcaaa guccuga                                          867


<210>  839
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  839
augcacaagu ggauccugac cuggauucuc cccacucugu uguacaggag cugcuuccau       60

aucauuuguc uggugggcac caucucccuc gccugcaacg acaugacgcc agagcagaug      120

gcaacuaaug ucaacuguag uagcccggaa cggcacaccc gcuccuauga uuacauggaa      180

gggggugaca uuagggugcg gcgccuguuu ugcaggaccc aaugguauuu gcggaucgau      240

aaacgcggca agguaaaagg gacucaggag augaagaaua acuacaauau cauggagauu      300

aggaccgugg ccgucggcau cguggcgauu aaaggugugg aaagugaguu cuaucuggcc      360

augaacaagg aggggaagcu cuacgccaaa aaggaaugua augaggacug caacuuuaaa      420

gaacugaucc uggagaauca uuauaacacg uacgcaagcg caaaguggac ucacaauggc      480

ggcgagaugu ucgucgcccu caaccagaaa gggauucccg ugcgggguaa gaaaaccaag      540

aaggaacaga aaacugcgca uuuucugcca auggccauca ccuga                      585


<210>  840
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  840
augaagcugc uccccagcgu gguccugaaa uuguuccugg ccgcagugcu cuccgcccug       60

guaaccggcg agaguuugga aaggcugcgg cgcgggcucg cggccgguac uagcaaccca      120

gacccgccca ccguguccac ggaucagcug cugccacucg gcgggggcag ggaccggaag      180

guccgcgauc ugcaagaggc agacuuggau cugcucaggg ugacucugag uagcaaaccc      240

caggcccugg caaccccaaa uaaggaggaa cacgguaaac ggaagaagaa agggaagggc      300

uugggcaaaa agcgcgaccc cugccucagg aaauacaagg auuuuuguau ccauggggaa      360

ugcaaauaug ugaaggagcu gcgggcccca uccuguauuu gccacccggg uuaccauggc      420

gagcgcuguc acgggcugag ccuccccguc gaaaacaggc uguauaccua cgaccauacu      480

accaucuugg cggugguagc cgugguccug uccagugugu gccuccuggu gauugucggc      540

cuguugaugu uccgguauca ccgcaggggu ggguacgaug uggagaauga agagaaggua      600

aaacucggca ugacgaacag ccacuga                                          627


<210>  841
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  841
auguggguga ccaagcugcu ccccgcccug uugcugcagc acguccuccu gcauuugcug       60

cuccugccaa ucgcaauucc guacgccgag ggccaaagga aacggcgcaa cacuauccac      120

gaauuuaaga aaagcgcgaa gaccacgcug auuaaaaucg accccgcccu caagauuaag      180

acuaaaaagg ugaauaccgc agaucagugc gccaacaggu guacccggaa uaaagggcug      240

ccauucacuu gcaaggcauu cguauuugac aaagcccgca agcaguguuu gugguucccc      300

uuuaacucca ugaguagcgg ugugaaaaag gaguucggcc augaauuuga ucuguaugag      360

aauaaggacu acaucaggaa cugcaucauu gggaaaggcc gguccuauaa ggguaccguc      420

aguaucacga aaagcgggau uaagugucag ccauggucca gcaugauccc ccacgaacau      480

uccuuccucc caaguagcua ccgcggcaaa gaucugcaag agaauuauug caggaacccg      540

cggggcgagg aagggggucc cugguguuuu acuuccaauc cagaggugcg cuacgaagug      600

ugcgacauuc cccaguguag cgaggucgag ugcaugaccu gcaacggcga aaguuauagg      660

gggcugaugg aucacacuga guccggcaag aucugucagc ggugggacca ccagacccca      720

caucgccaca aguucuugcc cgaaagguac ccggauaaag guuuugacga uaauuacugc      780

cggaaccccg acgggcaacc acgccccugg uguuauaccc ucgauccaca uacgaggugg      840

gaguacugcg cgauuaagac uugugccgac aauaccauga acgacacuga ugugccccug      900

gaaaccaccg agugcaucca gggccagggc gagggguauc gggguacugu aaauacgauc      960

uggaacggca uuccauguca gcgcugggac agccaauacc cgcacgaaca cgauaugacc     1020

cccgagaacu ucaaaugcaa ggaccugagg gaaaauuauu gucggaaccc agaugggucc     1080

gagagucccu ggugcuucac uaccgaccca aauaucaggg ugggcuacug cagccagauu     1140

cccaacugug auauguccca uggucaggac ugcuaucgcg gcaaugggaa aaacuacaug     1200

ggcaaucuca gccaaacccg gagugggcug acuuguucca ugugggauaa gaacauggaa     1260

gacuugcaca ggcauaucuu uugggagccg gaugcaagca agcugaauga gaacuacugc     1320

cgcaauccag acgacgaugc ccacgguccc ugguguuaua cgggcaaccc ccucauucca     1380

ugggacuacu gccccaucag ucggugugaa ggggauacca cuccaaccau cgucaaucug     1440

gaccauccgg ugauuuccug cgccaaaacc aagcagcuga ggguggucaa cggcaucccc     1500

acucgcacga auauugguug gauggugagc uugcgguaua ggaacaaaca caucuguggc     1560

gggagccuca uuaaggaguc cuggguacug accgcacggc agugcuuccc aagucgcgau     1620

cugaaagacu acgaagccug gcucggcauc cacgaugugc augggagggg cgacgagaag     1680

uguaagcagg uccugaacgu gagccaauug guguaugguc ccgaaggguc cgaucugguc     1740

cucaugaaac uggcgcggcc agccgugcug gacgauuuug uaagcacuau cgacuugccc     1800

aauuacggcu gcaccauucc ggagaagacc aguugcuccg uguaugguug gggcuacacu     1860

gggcucauca acuacgaugg ccugcugcgc gucgcacacc ucuauauuau ggggaaugag     1920

aaauguagcc agcaucacag gggcaaggug acgcugaacg aauccgagau cugcgccggu     1980

gcagagaaaa uugggagugg cccaugugaa ggcgacuacg ggggucccuu ggucugcgag     2040

cagcacaaga ugcggauggu gcugggcgug aucguaccag ggcgcggcug ugccauuccc     2100

aauaggccgg guaucuucgu gcgggucgcc uauuacgcga aauggaucca uaagauuauc     2160

cucaccuaua aggugcccca gagcuga                                         2187


<210>  842
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  842
auggccaagg cagccgcgau cggcauugac cuggggacca cuuacagcug cguggguguc       60

uuccagcacg gcaaagugga gaucauugcc aacgaucaag ggaauaggac cacgcccucc      120

uauguagcau uuacugacac cgaacggcuc aucggcgaug ccgcaaagaa ccagguggcc      180

cugaauccac agaacaccgu cuucgacgcg aaacgcuuga uugguaggaa guuuggggau      240

ccgguggugc agagugacau gaaacauugg cccuuccaag ucaucaauga uggcgacaag      300

ccaaaggugc agguaagcua caaaggcgag acuaaggccu uuuaucccga agagaucucc      360

aguauggugc ugaccaaaau gaaggaaauu gcagaggccu accucgggua uccagucacg      420

aacgccguga ucacugugcc cgcauacuuc aaugauagcc agcggcaggc caccaaagac      480

gcggguguca uugccggccu gaacguguug cgcaucauua augagccaac ugcagccgca      540

aucgccuaug ggcuggauag gaccggcaag ggugaacgga acguacucau uuuugaccuc      600

gggggcggca ccuucgaugu guccauccug acgaucgacg acgggauuuu ugaggucaaa      660

gccacugcgg gugauaccca ccugggcggg gaagacuucg auaaucgccu ggugaaccau      720

uuuguggagg aguucaagag gaagcacaaa aaggacauca gccaaaauaa acgggcaguc      780

cgcagguugc ggacugccug ugaacgcgcc aagaggaccc uguccaguag cacccaggca      840

ucccucgaga uugauagccu guucgaaggc aucgacuuuu acacuagcau uacgcgggcc      900

cgcuucgagg aacugugcuc cgauuuguuu aggagcaccc ucgagccggu ggagaaagcg      960

cugcgggacg ccaagcugga uaaggcacag auccaugacc ucguacuggu ggguggcucc     1020

acucgcaucc ccaaagucca gaaguugcug caagauuucu uuaacgggag ggaccucaau     1080

aaaaguauua acccagacga agccguggca uacggcgccg ccguccaggc agccauccug     1140

augggggaua agagcgagaa cgugcaggac cuguugcucc uggauguggc gccccugucc     1200

cucggucugg aaaccgccgg cgggguaaug accgcauuga uuaaacggaa uagcacuauc     1260

ccaacgaagc aaacccagau uuucacuacc uauagugaca accagcccgg cgugcugauc     1320

caggucuacg agggugaaag ggccaugacc aaggauaaua accuccuggg ccgcuuugag     1380

cuguccggga ucccgcccgc cccacggggc gugccccaaa uugaggucac uuucgacauc     1440

gaugcaaaug ggauuuugaa cgugacggcg accgacaaaa gcacuggcaa ggccaauaaa     1500

aucaccauua cuaacgauaa ggguaggcuc aguaaagaag agaucgaacg cauggugcag     1560

gaggcagaaa aguauaaggc cgaggacgag guacagcggg aaaggguguc cgccaaaaau     1620

gcacuggaga gcuacgccuu uaacaugaag agugcggucg aagaugaggg gcugaaaggc     1680

aagauuuccg aggccgacaa aaagaaagug cucgauaagu gucaggaagu caucaguugg     1740

cuggacgcaa auaccuuggc cgagaaggac gaguucgaac acaaacgcaa ggaacuggag     1800

caagugugca acccaaucau uagcggucuc uaucagggcg ccgggggccc cgggccaggc     1860

gguuuugggg cacagggccc gaaaggcggg uccgguagcg gccccacgau cgaggaagug     1920

gauuga                                                                1926


<210>  843
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  843
auggccaagg cagccgcgau cggcauugac cuggggacca cuuacagcug cguggguguc       60

uuccagcacg gcaaagugga gaucauugcc aacgaucaag ggaauaggac cacgcccucc      120

uauguagcau uuacugacac cgaacggcuc aucggcgaug ccgcaaagaa ccagguggcc      180

cugaauccac agaacaccgu cuucgacgcg aaacgcuuga uugguaggaa guuuggggau      240

ccgguggugc agagugacau gaaacauugg cccuuccaag ucaucaauga uggcgacaag      300

ccaaaggugc agguaagcua caaaggcgag acuaaggccu uuuaucccga agagaucucc      360

aguauggugc ugaccaaaau gaaggaaauu gcagaggccu accucgggua uccagucacg      420

aacgccguga ucacugugcc cgcauacuuc aaugauagcc agcggcaggc caccaaagac      480

gcggguguca uugccggccu gaacguguug cgcaucauua augagccaac ugcagccgca      540

aucgccuaug ggcuggauag gaccggcaag ggugaacgga acguacucau uuuugaccuc      600

gggggcggca ccuucgaugu guccauccug acgaucgacg acgggauuuu ugaggucaaa      660

gccacugcgg gugauaccca ccugggcggg gaagacuucg auaaucgccu ggugaaccau      720

uuuguggagg aguucaagag gaagcacaaa aaggacauca gccaaaauaa acgggcaguc      780

cgcagguugc ggacugccug ugaacgcgcc aagaggaccc uguccaguag cacccaggca      840

ucccucgaga uugauagccu guucgaaggc aucgacuuuu acacuagcau uacgcgggcc      900

cgcuucgagg aacugugcuc cgauuuguuu aggagcaccc ucgagccggu ggagaaagcg      960

cugcgggacg ccaagcugga uaaggcacag auccaugacc ucguacuggu ggguggcucc     1020

acucgcaucc ccaaagucca gaaguugcug caagauuucu uuaacgggag ggaccucaau     1080

aaaaguauua acccagacga agccguggca uacggcgccg ccguccaggc agccauccug     1140

augggggaua agagcgagaa cgugcaggac cuguugcucc uggauguggc gccccugucc     1200

cucggucugg aaaccgccgg cgggguaaug accgcauuga uuaaacggaa uagcacuauc     1260

ccaacgaagc aaacccagau uuucacuacc uauagugaca accagcccgg cgugcugauc     1320

caggucuacg agggugaaag ggccaugacc aaggauaaua accuccuggg ccgcuuugag     1380

cuguccggga ucccgcccgc cccacggggc gugccccaaa uugaggucac uuucgacauc     1440

gaugcaaaug ggauuuugaa cgugacggcg accgacaaaa gcacuggcaa ggccaauaaa     1500

aucaccauua cuaacgauaa ggguaggcuc aguaaagaag agaucgaacg cauggugcag     1560

gaggcagaaa aguauaaggc cgaggacgag guacagcggg aaaggguguc cgccaaaaau     1620

gcacuggaga gcuacgccuu uaacaugaag agugcggucg aagaugaggg gcugaaaggc     1680

aagauuuccg aggccgacaa aaagaaagug cucgauaagu gucaggaagu caucaguugg     1740

cuggacgcaa auaccuuggc cgagaaggac gaguucgaac acaaacgcaa ggaacuggag     1800

caagugugca acccaaucau uagcggucuc uaucagggcg ccgggggccc cgggccaggc     1860

gguuuugggg cacagggccc gaaaggcggg uccgguagcg gccccacgau cgaggaagug     1920

gauuga                                                                1926


<210>  844
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  844
auggccaccg caaagggcau cgccauuggg aucgaccugg guacuaccua cagcugcgug       60

ggcgucuucc agcacgggaa aguggagauu aucgcgaacg aucaaggcaa uaggacgacu      120

cccuccuaug uagccuuuac cgacaccgaa cggcucauug gugaugcagc caagaaccag      180

guggcaauga auccacagaa cacugucuuc gacgccaaac gccugaucgg gaggaaguuu      240

aaugauccgg uggugcaggc ggacaugaaa uuguggcccu uccaagucau caacgagggc      300

ggcaagccaa aggugcuggu aaguuacaaa ggggaaaaua aggccuuuua ucccgaggaa      360

auuagcucca uggugcucac caaacugaag gagacggcag aggccuucuu gggucaucca      420

gucacuaacg ccgugaucac cgugcccgca uacuuuaaug auagucagcg gcaggccacu      480

aaagacgcgg gcgucauugc cgggcugaac gugcuccgca ucauuaauga accaaccgca      540

gccgcaaucg ccuauggccu ggauaagggu gggcagggcg agaggcacgu acugauuuuc      600

gaccucggcg gggguaccuu ugaugugagc auccugacga ucgacgaugg cauuuucgaa      660

gucaaagcca cugcggggga cacccauuug ggcggugagg acuuugauaa ccggcuggug      720

ucccacuucg uggaggaguu caagcgcaag cauaaaaagg acaucagcca aaauaaaagg      780

gcaguccggc gccucaggac ugccugugag cgggccaagc gcacccuguc caguagcacc      840

caggcaaacc uggaaauuga uuccuuguac gagggcaucg acuuuuauac uagcauuacg      900

agggcccggu ucgaagaacu cugcgcggau cuguuucgcg ggacccugga gccgguggaa      960

aaagcccuca gggacgcaaa gauggauaag gccaaaaucc acgacaucgu acuggugggc     1020

gggaguacuc ggauucccaa gguccagcgc uugcugcagg auuacuucaa ugguagggac     1080

cucaacaaau ccaucaaccc agaugaggca guggccuacg gcgccgcagu ccaagccgcg     1140

auucugaugg gggacaagag cgaaaaagug caggaccugu ugcuccugga uguggcaccc     1200

cugucccucg gccuggagac cgccgguggc guaaugaccg ccuugaucaa gcggaauagu     1260

acuauuccaa cgaagcagac ccaaaucuuu acuaccuaua gcgacaacca gcccggggug     1320

cugauccagg ucuacgaagg cgagagggcc augaccaaag auaauaaccu ccuggggcgc     1380

uucgaccuga cuggcauucc gcccgcacca cggggugugc cccagaucga ggucacguuu     1440

gauauugacg cgaaugggau cuugaacgug accgccacug auaaguccac cggcaaagug     1500

aauaagauua cuaucaccaa cgacaaaggu aggcucagca aggaagagau ugaacgcaug     1560

guacuggaug cagagaagua uaaagccgaa gacgaggugc aacgggagaa gaucgccgcc     1620

aaaaaugcac uggaaaguua cgcguucaac augaaguccg ucgugagcga ugagggccuc     1680

aaagggaaga ucagugaauc cgacaaaaau aagauucugg auaaguguaa cgaguugcug     1740

agcuggcucg aggucaauca gcuggccgaa aaagacgagu uugaccacaa gaggaaagaa     1800

cuggagcaga ugugcaaccc aaucauuacg aaguuguauc agggcgggug uaccggcccc     1860

gcaugcggua cuggguacgu gccaggccgc ccggccaccg gccccacuau cgaagaggug     1920

gauuga                                                                1926


<210>  845
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  845
augagcgcca ggggccccgc aaucgggauu gaccugggua ccacuuacuc cugcgugggc       60

gucuuccagc acgggaaggu ggagaucauu gccaacgauc agggcaaucg gaccacgcca      120

aguuauguag cguuuacuga caccgaacgc cucaucggug augccgccaa aaaccaggug      180

gcaaugaauc cgaccaacac uauuuucgac gcaaagaggc ugaucgggcg gaaauuugag      240

gaugccaccg uccagagcga caugaagcau uggcccuucc gcgugguguc cgaaggcggc      300

aaaccaaagg uccaggugga guacaagggg gaaacgaaaa ccuuuuuccc cgaggagauc      360

aguagcaugg uauugacuaa gaugaaagaa auugcggagg ccuaucuggg uggcaaggug      420

cacuccgcag ucaucacugu gccagccuac uuuaaugaua gccaaaggca ggccaccaaa      480

gacgcaggga ccauuacggg ccucaacgug cugcggauca uuaaugaacc cacugccgcg      540

gccaucgcau augguuugga uaagaaaggg ugugccggcg gcgagaagaa cguccugauu      600

uucgaccucg gggguggcac cuuugaugug uccauccuga cuaucgagga cgggauuuuc      660

gaaguaaaga guaccgcagg cgauacccau cuggguggcg aggacuuuga caaucgcaug      720

gugagccacc ucgccgaaga guucaaaagg aagcauaaaa aggauaucgg gccaaacaaa      780

cgggccgucc gcaggcugcg gacugcgugc gaacgcgcaa agaggacguu guccagcagu      840

acccaggccu ccauugagau cgacagccug uacgagggcg uggauuucua uacuuccauu      900

acccgggccc gcuuugagga acucaaugca gaccuguuca gggggacccu ggaaccggug      960

gagaaggccu ugcgggaugc gaaacucgac aagggucaga uccaagaaau cguccuggug     1020

ggcgggagua cucgcauucc caaaauccag aagcugcucc aggacuuuuu caacggcaaa     1080

gagcugaaua agagcauuaa cccagaugag gccguagcau acggugccgc agugcaggcc     1140

gccaucuuga uuggcgauaa guccgaaaau guccaagacc ugcuccugcu ggaugugacg     1200

cccuugagcc ucgggaucga gaccgcaggc ggggucauga cuccacugau caaaaggaac     1260

accaccauuc ccacuaagca gacgcagacc uuuacuaccu acagugacaa ccaauccagc     1320

gugcuggugc agguauauga aggcgagcgg gccaugacua aagacaauaa ccuccugggu     1380

aaguucgauu ugaccgggau cccgcccgcg ccaaggggcg ugccccagau ugaagucacg     1440

uuugacaucg augccaaugg uauucugaac gugaccgcag ccgacaaaag uacuggcaag     1500

gagaauaaga ucaccauuac uaacgauaaa gggcgccucu ccaaggacga uaucgaccgg     1560

augguccagg aggccgaaag guacaaaagc gaggaugaag caaaucgcga ccggguggcg     1620

gccaagaacg cacuggagag cuauaccuac aauaucaaac aaacggugga ggaugaaaag     1680

cugaggggca aaauuuccga gcaggacaag aacaagaucu uggauaaaug ucaggaagua     1740

auuaauuggc ucgaccgcaa ccagauggcc gagaaggacg aauaugagca caaacaaaag     1800

gagcuggaac gggugugcaa uccaaucauu aguaaacugu accaaggggg ccccgguggg     1860

ggcagcggcg gggguggcuc cggggccagc ggcgguccaa ccaucgagga agucgauuga     1920


<210>  846
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  846
augagcgugg ucggcaucga ccugggguuc caguccugcu acguggccgu agcaagggcc       60

gguggcauug agaccaucgc gaacgaauau agugaucggu guacucccgc cugcauuagc      120

uuugggccaa agaaucgcuc caucggcgca gccgcaaaaa gucaagugau uagcaacgcc      180

aagaauaccg uccaggguuu caaaagguuu cacgggcggg cguucuccga cccguuugug      240

gaggccgaaa agagcaaccu cgcauacgau aucgugcagc ugcccacggg cuugacuggc      300

aucaaaguca ccuauaugga ggaagaacgc aauuucacca cugaacaggu gaccgccaug      360

cugcucucca agcugaagga aacggccgag aguguauuga aaaagccagu ggucgacugu      420

guggugagcg uccccugcuu uuacacugau gcagaaaggc gguccgugau ggacgccacc      480

caaauugcgg ggcugaacug ucuccgccug augaaugaga cuaccgccgu agcacuggcc      540

uaugguaucu acaaacagga ucucccagca cuggaggaaa agcccaggaa cguggucuuc      600

guggacaugg gccauagcgc cuaucaggug agugucugcg ccuuuaaucg ggggaaauug      660

aaggugcugg cgaccgcauu cgauacgacu cucggcgguc gcaaauuuga cgagguacug      720

gugaaccacu ucugugaaga guucgggaag aaguacaaac uggauauuaa guccaaaauc      780

agggccuugc uccggcugag ccaggaaugc gagaagcuga aaaagcucau guccgccaau      840

gcaagugacc ugccauugag cauugagugu uuuaugaacg augucgacgu guccggcacc      900

augaaucgcg gcaaguuccu ggaaaugugc aacgaccucc uggccagggu cgagccgccc      960

cugcggagcg uguuggaaca aacuaaacuc aagaaagagg auaucuacgc gguggaaauu     1020

guagggggug ccacccgcau cccagcagug aaggagaaaa ucaguaaguu uuucggcaag     1080

gagcugucca ccacucugaa ugccgacgaa gcagucacga gggggugcgc ccuccagugu     1140

gccauucuga gccccgcauu uaaagugcgg gaguucagua ucaccgaugu cgugccauau     1200

cccauuuccu ugcgcuggaa cagcccggcc gaagagggca gcuccgacug cgaaguguuu     1260

aguaagaacc augcggcccc cuucagcaaa guacugacuu uuuacaggaa ggagccauuc     1320

acccucgagg cauauuacuc cagcccccag gaucugccau aucccgaccc agccaucgcc     1380

caguuuagug ugcaaaaagu caccccgcag uccgauggua gcuccaguaa ggugaagguc     1440

aaagugcggg ugaauguaca cggcauuuuc agcgucucca gcgcaagucu gguggaagug     1500

cauaaguccg aggaaaacga ggagcccaug gaaacugacc agaaugcgaa agaggaagag     1560

aagaugcaag ucgaucagga ggagccacac guggaggaac agcagcaaca gacgcccgcc     1620

gagaacaaag cagaaagcga ggaaauggag accucccagg ccgggaguaa ggacaaaaag     1680

auggaucagc caccccaagc caagaaagca aaggugaaaa cuagcaccgu agacuugccg     1740

aucgagaauc agcuccugug gcagaucgac agggaaaugc ugaaccucua cauugagaau     1800

gaaggcaaga ugaucaugca ggauaaacug gagaaggaac gcaacgacgc caagaaugcg     1860

gucgaggagu auguguacga aaugcgggau aaauuguccg gggaguacga aaaguuugug     1920

agcgaggacg auaggaacag uuucacccug aaacucgagg acacugaaaa uuggcuguau     1980

gaggauggug aagaccaacc aaagcagguc uacguggaua aacuggccga guugaagaac     2040

cugggccagc ccauuaagau ccgcuuccag gaauccgagg agcggcccaa acucuuugag     2100

gagcugggga agcaaauuca gcaguauaug aaaaucauca gcuccuucaa gaauaaagaa     2160

gaccaauacg aucaccucga cgcagccgau augacgaagg uagagaaaag caccaacgaa     2220

gccauggagu ggaugaauaa caagcugaac uugcagaaua agcagagucu gacuauggac     2280

ccagugguca aaagcaagga gauugaagca aaaaucaagg agcucaccuc cacuuguagu     2340

cccauuauca gcaaaccaaa gccgaaggug gaacccccaa aagaggagca gaagaacgcc     2400

gaacaaaaug gccccgugga cggucagggc gauaacccag ggccccaggc ggccgagcag     2460

ggcaccgaca cggcaguccc guccgauagc gacaaaaagc ugccagaaau ggauauugac     2520

uga                                                                   2523


<210>  847
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  847
augagcgugg ucggcaucga ccugggguuc cucaacugcu acauugccgu ggcaaggucc       60

gguggcaucg agaccauugc caaugaauau agugaucggu guacucccgc gugcaucagc      120

cugggguccc gcaccagggc cauuggcaac gcagccaaga gucagaucgu aacgaaugug      180

cggaacacua uccacgguuu uaaaaaguug caugggcgca gcuucgacga uccaauuguc      240

caaaccgaga ggauccggcu gccguacgaa cuccagaaaa ugcccaaugg cuccgcaggc      300

gugaaggugc gcuaucugga ggaagagagg ccauuugcca uugagcaggu caccgggaug      360

uugcuggcga aacucaagga aacuagcgag aacgcccuga agaaacccgu ggcagacugu      420

guaaucucca uuccaaguuu cuuuaccgau gccgaacggc gcagcgugau ggccgcagcc      480

caggucgcgg gucugaauug ccucaggcug augaacgaga cgacugccgu ggcauuggcc      540

uacggcaucu auaagcaaga ccugccccca cucgaugaga aaccgcggaa uguggucuuc      600

auugacaugg ggcacuccgc auaccaggug cugguaugug ccuuuaacaa gggcaaacug      660

aagguguugg ccaccacuuu cgaucccuau cucggugggc gcaauuuuga cgaagcgcug      720

gucgauuacu ucugcgacga guuuaaaacc aaguacaaga ucaacgugaa agaaaauagc      780

agggcacugc uccggcugua ucaggagugu gaaaaguuga aaaagcugau gagugccaac      840

gccuccgauc ucccacugaa uaucgagugc uucaugaacg accuggacgu gagcuccaaa      900

augaaccgcg cacaguucga gcaauugugu gccagucucc uggcgagggu cgaaccccca      960

cugaaggccg ugauggagca ggcaaaucuc cagcgggaag auauuagcuc caucgagauu     1020

guaggcggcg ccacccgcau ccccgcagug aaggaacaga uuacgaaauu uuuccugaag     1080

gacaucagca cuaccuugaa cgccgaugag gccgucgcaa gggggugcgc ccugcaaugc     1140

gcgauccuca guccggccuu uaaagugcgg gaguucucca uuacugaccu gguccccuac     1200

agcaucaccc ugagguggaa gaccaguuuu gaagaugguu ccggcgagug ugaaguguuc     1260

ugcaaaaauc auccagcacc cuuuagcaag gugauuacuu uccacaagaa agagccauuu     1320

gaauuggagg ccuucuauac gaaccuccau gagguacccu acccagacgc ccgcaucggg     1380

agcuuuacca uucagaaugu guucccgcag uccgauggcg acaguagcaa ggucaaagug     1440

aagguccggg ugaacaucca cgguaucuuu uccguggcaa gcgcgagugu aauugaaaaa     1500

caaaaucugg agggcgauca cuccgacgcc cccauggaaa cugagaccag cuucaagaac     1560

gagaauaagg auaacaugga caaaaugcaa guggaccagg aagaggggca ucagaagugu     1620

cacgcagaac auaccccaga ggaagagauc gaucacacug gcgccaaaac gaaguccgcc     1680

gucagugaca aacaggauag gcugaaucag acccucaaga aagggaaggu gaaguccauu     1740

gaccugccca uccaguccag cuugugccgc cagcuggguc aagaucuccu gaacaguuau     1800

auugagaaug aaggcaaaau gaucaugcag gacaagcugg agaaagaacg gaacgaugca     1860

aagaaugccg ucgaggaaua cguguaugac uucagggauc gcuuggggac uguguacgag     1920

aaauuuauua ccccagagga ccuguccaag cucagcgcgg uacuggaaga uaccgagaac     1980

uggcucuacg aagacggcga ggaucagccc aagcaggucu auguggacaa acugcaagaa     2040

uugaagaaau acggucagcc gauccagaug aaguauaugg agcacgagga acggccaaaa     2100

gcccugaacg accucggcaa gaagauccag cuggugauga aagucauuga ggcauacagg     2160

aauaaggaug aacgguauga ccaucuggau cccacugaga uggagaaagu ggaaaagugu     2220

aucuccgacg ccaugaguug guugaacagc aaaaugaaug cccaaaacaa gcugucccuc     2280

acgcaggauc ccgugguaaa agucagcgag auuguggcaa agaguaagga acuggacaau     2340

uucugcaacc caaucauuua caaacccaag ccaaaagccg aggugccgga agauaagccc     2400

aaagcgaaua gcgagcacaa cgggccaaug gacggccaga gcgggaccga gacuaagucc     2460

gauagcacca aggacaguag ccaacauacu aaauccagug gcgaaaugga ggucgauuga     2520


<210>  848
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  848
augaagcuga gccucguggc cgcaaugcug uugcugcucu ccgccgcgag ggccgaggaa       60

gaggacaaaa aggaagaugu cggcaccgug guagggaucg accuggguac uaccuacagu      120

ugcgugggcg ucuucaaaaa cgggcgggug gagauuaucg caaaugauca gggcaaccgc      180

auuacgccca gcuauguggc cuuuacucca gaaggugaga gguugaucgg ggacgcagcc      240

aagaaucaac ugaccuccaa cccggagaau accgucuucg augcgaaacg gcucauuggc      300

cgcacuugga acgaccccag ugugcagcag gauaucaagu uucugccauu caagguagug      360

gagaaaaaga ccaaacccua cauccagguc gacauuggcg ggggucaaac gaagacuuuu      420

gccccagaag aaaucagcgc aauggugcug accaaaauga aggagacugc cgaggccuau      480

cucggcaaaa aggugaccca cgcagucgug accguacccg ccuacuucaa ugaugcgcag      540

aggcaggcca cgaaggacgc agggacuauu gccggccuga acgugaugcg gaucauuaau      600

gaaccaaccg cagccgccau cgcguauggu uuggauaaac gcgaggggga aaagaacauu      660

cuggucuuug accucggcgg cgggacuuuc gauguguccc ugcugaccau cgacaauggu      720

guguuugagg ucguggcaac caacggcgac acucaucucg ggggcgaaga uuucgaccag      780

aggguaaugg agcacuuuau caaauuguac aagaaaaaga cggguaagga ugugcggaaa      840

gacaaucgcg ccguccaaaa gcugaggcgg gagguggaaa aagccaagcg cgcacugagc      900

ucccagcauc aggccaggau ugagaucgaa aguuucuaug agggcgaaga uuucagcgag      960

acccucacuc gggcgaaauu ugaggaacug aacauggacu uguuccgcuc caccaugaag     1020

ccgguccaga aggugcugga ggauagcgac cucaaaaaga gugauauuga cgaaaucgug     1080

cugguagggg gcuccaccag gauucccaaa auccaacagc uggugaagga guuuuucaau     1140

gggaaagaac caagccgggg uaucaacccc gaugaggccg ucgcauacgg cgccgcagug     1200

caggccgggg ucuuguccgg cgaccaagac acuggugauc ucgugcugcu ggacgugugu     1260

ccacucacgc ugggcauuga gaccguaggg ggcgugauga cuaaguugau cccccgcaac     1320

accgucgugc cgaccaagaa aagucagauu uuuagcacug ccuccgauaa ucagcccacg     1380

gucaccauca agguguacga aggggagagg ccacugacua aagacaacca ccuccugggc     1440

accuucgauc ugacugguau ucccccagca ccccggggcg ugccacagau cgaaguaacc     1500

uuugagaucg acgucaaugg gauuuugagg gugacggccg aggauaaggg uaccggcaac     1560

aaaaauaaga ucacuauuac caacgaccaa aaucgccuca cuccggaaga gaucgaacgg     1620

auggugaacg augcggagaa auucgccgaa gaggacaaga agcugaaaga gaggauugau     1680

acccgcaaug aacuggagag cuaugcauac agucucaaga accagaucgg ggacaaagaa     1740

aagcugggcg ggaaauuguc cagcgaggau aaggaaacga uggagaaggc cgucgaggag     1800

aaaauugaau ggcuggaaag ucaucaggac gccgacaucg aggauuuuaa ggcgaaaaag     1860

aaagaacucg aggagaucgu gcagcccauu aucuccaagc uguauggcag cgcaggucca     1920

cccccaaccg gggaagagga cacugccgaa aaggaugagc uguga                     1965


<210>  849
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  849
augcaggccc ccagggagcu ggcagugggc aucgaccucg ggaccacuua cagcugcguc       60

gguguguucc aacagggccg gguagaaauu cuggccaacg aucaggggaa ucgcaccacg      120

ccauccuaug uggcguuuac ugacaccgag agguuggucg gcgaugccgc aaagagucag      180

gccgcacuga acccgcacaa uaccguguuc gacgccaaac ggcucaucgg ucgcaaguuu      240

gcggauacua ccgugcaaag cgacaugaaa cauuggcccu ucagggucgu guccgaaggg      300

ggcaagccaa aaguacgggu guguuaccgc ggcgaggaua agacguuuua ucccgaagag      360

auuaguagca ugguccuguc caagaugaaa gagacugccg aagcauacuu ggggcagcca      420

gugaagcacg ccgugaucac cguccccgcc uauuucaacg acagccagag gcaggcaacu      480

aaagaugccg gugcgauugc cggccugaau gugcuccgga ucaucaacga gccaaccgca      540

gccgcaauug ccuacgggcu ggaccgcagg ggcgccggug aacggaaugu acugaucuuu      600

gaucucgggg gcggcaccuu cgacgugucc guccugagua uugaugcggg gguguuugag      660

gugaaggcaa cggccgguga cacucauuug ggcggggagg acuucgauaa ccgccugguc      720

aaucacuuua uggaagaguu caggcggaaa cauggcaagg accucagcgg uaacaaacgc      780

gcccugaggc ggcugcgcac cgcaugcgaa agggccaagc ggacuuuguc cagcaguacc      840

caagcgaccc ucgagaucga uucccuguuc gaaggcgugg acuuuuauac uagcauuacg      900

agggcccgcu ucgaggagcu guguuccgau cucuuucgga guacccugga accgguagag      960

aaggcauuga gggacgccaa acuggauaag gcacagaucc acgacguggu ccucgucggg     1020

ggcagcacuc gcauucccaa agugcagaag cugcugcagg auuucuuuaa ugggaaagaa     1080

uugaacaagu ccaucaaucc agacgaggcc guggccuacg gugcagccgu gcaagcggcc     1140

guacucaugg gcgauaagug cgaaaaagug caggaccugc ugcuccugga cgucgcaccc     1200

uugagccugg ggcucgagac cgccggcggu gugaugacca cucugaucca gcggaacgcc     1260

acgauuccaa ccaagcaaac ucagaccuuc accacuuaca gugauaauca gcccggcguc     1320

uuuauccagg uguaugaggg ggaaagggca augacgaaag acaacaaccu guugggccgc     1380

uucgagcucu ccgggauucc gcccgcgcca cggggcgugc cccaaaucga aguaaccuuu     1440

gauauugacg ccaaugguau ccugagcgug acugcaaccg auaggaguac ugggaaggcc     1500

aacaaaauca ccauuacgaa ugacaagggc cggcugucca aggaggaagu cgagcgcaug     1560

gugcacgagg ccgaacagua caaagcagag gaugaagccc agagggaccg ggucgcggcc     1620

aagaacagcc ucgaggcaca uguguuccac gugaaaggua gccugcagga ggaauccuug     1680

cgcgauaaga ucccagagga agacaggcgg aaaaugcaag auaagugucg cgagguacug     1740

gccuggcucg aacauaauca gcuggccgag aaggaggaau augagcacca gaaaagggaa     1800

cuggagcaga uuugccggcc caucuuuagu agguuguacg gcgggccagg cguccccggg     1860

ggcagcuccu gugguaccca agcacgccag ggggacccga gcacuggccc aauuaucgaa     1920

gagguggauu ga                                                         1932


<210>  850
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__P48741__HsHSPA7

<400>  850
augcaggccc ccagggagcu ggcagugggc aucgaccucg ggaccacuua cagcugcguc       60

gguguguucc aacagggccg gguagaaauu cuggccaacg aucaggggaa ucgcaccacg      120

ccauccuaug uggcguuuac ugacaccgag agguuggucg gcgaugccgc aaagagucag      180

gccgcacuga acccgcacaa uaccguguuc gacgccaaac ggcucaucgg ucgcaaguuu      240

gcggauacua ccgugcaaag cgacaugaaa cauuggcccu uccaggucgu guccgaaggg      300

ggcaagccaa aaguaagggu guguuaccgg ggcgaggaua agacguuuua ucccgaagag      360

auuaguagca ugguccuguc caagaugaaa gagacugccg aagcauacuu ggggcagcca      420

gugaagcacg ccgugaucac cguccccacu uauuucagca acucccagcg ccaagccacc      480

aaagacgcag gggccauugc gggccugaag gugcucccaa ucaucaauga ggccaccgca      540

gccgcaauug ccuacgggcu ggauaggcgg ggcgccggua aacgcaacgu acugaucuuu      600

gaccucgggg gcggcacguu cgaugugagu guccugagca uugacgcggg gguguuugaa      660

gugaaggcaa cugccgguga uacccauuug ggcggggagg acuucgacaa uaggcugguc      720

aaccacuuua uggaggaguu ccggcgcaaa cauggcaagg aucucuccgg uaauaagagg      780

gcccugcggc gccugaggac ugcaugcgag cgggccaaac gcaccccgag caguuccacc      840

caggcgacuu uggaaaucga cagccucuuc gagggcgugg auuuuuauaa guccauuacg      900

agggcccggu ucgaagaacu guguagugac cuguuuagga gcacccucga gcccguagaa      960

aaagcacugc gcgaugccaa guuggacaaa gcacagaucc acgauuucgu gcuggguggc     1020

gggcuccacu cccauccaca gggugccgag gucgccgcag gccugcugca acggcagggg     1080

gccgaacagg agcaccaacc cuga                                            1104


<210>  851
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  851
augagcaagg gccccgccgu ggggaucgac cuggguacca cuuacuccug cgucggcgug       60

uuccagcacg ggaaaguaga gauuaucgca aacgaucaag gcaauaggac cacgccaagu      120

uauguggccu uuacugacac cgaacggcuc auuggugaug cggccaagaa ccaggucgca      180

augaauccga ccaacacugu guucgacgcc aaacgccuga ucgggaggcg guuugaugac      240

gcaguggucc agagcgauau gaagcauugg cccuucaugg ugguaaauga cgccggccgc      300

ccaaaagugc aggucgagua caagggcgaa accaaguccu uuuaucccga ggaagugagu      360

agcauggugu ugacgaaaau gaaggagauu gcggaggccu accuggggaa aacugucacc      420

aacgcagugg uaacugugcc agccuauuuc aaugauuccc aaaggcaggc caccaaggac      480

gcagguacca ucgccggccu caacguccug cggaucauua augaacccac ggcggccgca      540

aucgccuacg gguuggauaa aaaggugggc gcagagcgca acgugcugau uuuugaccuc      600

ggugggggca cuuucgaugu cagcauccug accauugaag acggcaucuu ugaggugaaa      660

uccacugccg gggacaccca ccuggguggc gaggauuucg acaauaggau gguaaaccau      720

uuuauugccg aauuuaagcg gaagcacaaa aaggauauca gugagaauaa acgcgcggug      780

aggcggcucc gcaccgcaug ugaaagggcc aagcggacuc ugagcuccag cacgcaggcc      840

aguaucgaga uugacuccuu guaugaaggg aucgauuucu acaccagcau uacucgcgca      900

agguuugagg agcugaacgc cgaccucuuc cggggcaccc uggauccagu cgaaaaagcg      960

cugcgcgacg ccaaguugga uaagucccag auccaugaca uugugcucgu cgguggcagu     1020

accaggaucc cgaaaaucca aaagcugcug caggauuucu ucaaugggaa agagcucaac     1080

aagagcauua accccgacga agcaguggcc uacggcgcag ccgugcaggc cgcaauccug     1140

uccggggaca aaagcgagaa uguacaggau uugcugcucc uggacgugac uccacugagu     1200

uuggguauug aaacggccgg cggggucaug accgugcuca ucaagcggaa cacuaccauu     1260

cccaccaagc aaacucagac guuuaccacu uauuccgaua aucagccagg cguccugauc     1320

caaguguacg agggugagag ggcgaugacc aaagacaaca aucugcucgg caaguucgaa     1380

cugacuggga uucccccggc accccgcggc gugccacaga ucgagguaac cuuugauauc     1440

gacgccaacg ggauuuugaa ugugagcgcc gucgauaaaa guacgggcaa ggaaaacaaa     1500

aucaccauua cuaaugacaa gggucggcug uccaaggagg auaucgaaag gauggugcag     1560

gaggccgaga aauauaaggc agaagacgag aaacagcgcg auaaggucag cagcaaaaac     1620

ucccucgaaa guuacgcguu caauaugaag gccaccgugg aggacgagaa acugcaaggg     1680

aagauuaacg augaagacaa gcagaaaauc cuggacaagu gcaaugagau cauuaacugg     1740

uuggauaaaa aucagacugc agaaaaggag gaauuugagc accagcaaaa agagcucgaa     1800

aaggugugua accccaucau uaccaagcug uaucagagcg ccggcgguau gccaggcggg     1860

augcccggcg gguucccagg cgguggggcc ccgcccuccg gcggcgcaag cagugggcca     1920

acgaucgagg aaguagacug a                                               1941


<210>  852
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  852
augaucagcg ccuccagggc agccgcggcc cggcuggugg gcgcagccgc aagucgcggg       60

cccaccgccg cgaggcacca ggacagcugg aacggucucu cccaugaggc cuuccggcug      120

gucagucgca gggauuacgc aagcgaagcc auuaagggcg ccgugguagg gaucgacuug      180

ggcacuacca auuccugcgu ggcagucaug gaggguaaac aagccaaggu gcuggaaaac      240

gcggaggggg cccggacgac uccaagcgug gucgcauuua ccgccgaugg cgaacgccuc      300

gugggcaugc cggcaaaaag gcaggccgua accaauccca acaauacuuu cuaugccacc      360

aagcggcuga uugggcgcag guacgacgau ccagaggugc agaaagacau caagaacguc      420

cccuuuaaga uugugcgggc guccaauggu gaugcauggg uggaggccca cggcaaauug      480

uauaguccaa gccagaucgg ggccuucguc cugaugaaga ugaaagaaac ggcagagaac      540

uaccucggcc auacugccaa gaaugcggug aucaccguac ccgccuauuu uaacgacucc      600

caacgccagg caacuaaaga ugccggucag auuagcgggc ugaaugugcu gagggucauc      660

aacgaaccaa ccgcagccgc ccucgcauac ggccuggaca agagugagga uaaagugauu      720

gccguguaug acuugggcgg ggguaccuuc gauaucucca uucuggagau ccagaagggc      780

gucuuugaag uaaagagcac gaauggggac acuuuccucg gcggugagga cuuugaucaa      840

gcgcugcugc ggcacauugu gaaagaguuc aagcgcgaaa ccggcgugga cuugacuaaa      900

gauaacaugg cccuccagag gguccgggaa gcagccgaga aggccaaaug ugagcugucc      960

aguagcgugc agaccgacau caaucugccg uaccucacca uggauuccag cgggcccaag     1020

caucugaaca ugaaguugac ucgcgcacag uuugaaggca ucgucacgga ccugauuagg     1080

cggaccaucg cgccaugcca aaaagccaug caggaugcag aggugaguaa guccgacauu     1140

ggggaaguga uccucguagg uggcaugacu aggaugccca aagugcagca aaccguccag     1200

gaucuguucg ggcgcgcccc aagcaaggcc gugaaccccg acgaggcagu cgccauuggc     1260

gcggccaucc aggguggcgu gcuggcaggg gaugugaccg acguauugcu ccuggacgug     1320

acuccgcuga gucucggcau cgaaacgcug ggcggggucu ucaccaaauu gauuaaucgg     1380

aacacuacca uccccaccaa gaagucccag guguuuagca cugccgccga uggucaaacg     1440

caggucgaga uuaaagugug ucagggggag agggaaaugg caggcgacaa uaagcugcuc     1500

ggucaguuca cccugaucgg cauuccaccc gccccacgcg gggugcccca aaucgaggua     1560

acuuuugaua ucgacgcgaa cggcauuguc cacgugagcg ccaaagauaa ggggaccggc     1620

cgggaacagc agaucgugau ucaguccagu ggugggcuga gcaaagacga uaucgagaau     1680

auggucaaga acgcagaaaa guacgccgag gaggacaggc gcaaaaagga acggguggag     1740

gcagugaaua uggccgaagg cauuauccac gauacugaga ccaaaaugga ggaguucaag     1800

gaccaauugc cagcggauga augcaacaaa cucaaggaag agauuuccaa aaugagggaa     1860

cugcuggccc ggaaggacag cgagacgggc gagaauaucc gccaggcagc caguucccuc     1920

cagcaggcca gccugaaguu guuugaaaug gcauauaaaa agauggccuc cgagagggaa     1980

gggaguggua gcuccggcac cggggagcaa aaagaagauc agaaggagga gaaacaguga     2040


<210>  853
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  853
auggccgaca aggaggcagg cgggagcgau ggucccaggg aaaccgcccc aacuuccgcg       60

uacaguagcc cggcccgguc ccugggcgac accgggauca cgccccucag uccaagccac      120

auugugaacg auacugacuc caaugucagc gagcagcaau ccuuccuggu gguaguggca      180

gucgauuuug gcaccaccag uagcgguuau gccuacuccu ucacuaaaga acccgagugc      240

auccauguga ugaggcgcug ggaagggggc gacccaggcg ugagcaacca gaagaccccc      300

acgacuauuu ugcugacccc agagcggaaa uuucacaguu ucggguaugc agcccgcgau      360

uuuuaccaug accucgaucc gaaugaggcg aagcaguggc uguauuugga aaaauucaag      420

augaagcugc acacuaccgg ugaccucacc auggauacgg accugacugc cgcaaacggc      480

aaaaagguca aagcccugga gaucuuugcc uacgcacucc aguauuucaa ggaacaagcc      540

cugaaagagu uguccgauca ggcggggagc gaguuugaaa auuccgacgu gaggugggua      600

auuaccgugc ccgccaucug gaagcagcca gcaaaacagu ucaugcggca agccgcauac      660

caggccggcc uggccagucc cgagaacagc gaacagcuca ucauugcgcu ggagccagaa      720

gcagccucca ucuacugucg caagcugagg uugcaucaga ugauugagcu cagcaguaag      780

gccgcaguca augguuauuc cgggagcgac acugugggcg ccggcuuuac ccaagcgaaa      840

gagcacaucc ggcgcaacag gcagagucgg accuuccugg uggaaaaugu cauuggggag      900

aucugguccg aacuggagga aggugauaag uacgugguag uggacagcgg cgggggcacu      960

gucgaucuca cggugcacca gauucgccug cccgaggguc auuugaaaga gcuguauaag     1020

gccaccggcg ggccguacgg cagccucggg guggacuaug aguucgaaaa acugcuguac     1080

aagaucuuug gugaagauuu caucgagcaa uuuaagauua aaaggcccgc agccuggguc     1140

gacuugauga ucgcauucga aucccggaag cgcgccgccg caccagauag gacuaacccc     1200

cucaauauua cccugccauu uaguuucauc gacuauuaca aaaaguuucg gggccacagc     1260

guggagcaug cccugcgcaa auccaacgua gauuucguga aguggagcag ucaggggaug     1320

cucaggaugu cccccgacgc gaugaaugcc cuguuuaagc caaccauuga uagcaucauc     1380

gagcacuugc gggaccuguu ccagaaaccg gaagucucca cugugaaguu ucucuuccug     1440

gucggcgguu uugcagaggc accccuguug cagcaagccg ugcaggccgc guucggcgac     1500

cagugcagga uuaucauucc acaggaugug gggcucacga uccugaaagg cgccguacug     1560

uucgggcucg accccgcagu gauuaagguc cgccggaguc cacugaccua cggcgugggu     1620

gucuugaaca gguaugugga agggaaacau cccccggaga agcugcucgu gaaggauggc     1680

acucgcuggu guaccgacgu auuugauaaa uucaucagcg ccgaccaauc cguggcccug     1740

ggugagcugg ucaagcggag cuacacccca gcaaaaccca gucaguuggu gaucgucauu     1800

aauaucuauu ccagcgaaca cgauaacgug uccuuuauua cugaccccgg cgugaagaaa     1860

ugcgggacgc ugaggcucga ucugaccggc accaguggga cugccguacc agcgcgccgg     1920

gagauccaga cucucaugca guucggcgac accgaaauua aggccacggc aaucgauauu     1980

gccaccagca aauccgucaa gguggguauc gacuuucuga acuacuga                  2028


<210>  854
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  854
augcuggccg ugcccgagau gggccuccag gggcuguaca ucgguagcuc cccagaaagg       60

aguccggucc ccagcccacc cggcucccca cggacccaag agaguugcgg gauugcaccc      120

uugacuccaa gccagucccc gaagcccgaa gugcgcgccc cacagcaggc gagcuucucc      180

guaguggucg ccaucgacuu uggcaccacg aguagcgguu augcauucuc cuuugccagc      240

gaucccgagg caauucacau gaugaggaaa ugggaagggg gcgacccagg cguggcccau      300

caaaagacuc ccaccugucu gcuccugacc ccggaggggg cguuccacag uuuugguuac      360

acugcccggg auuauuacca ugacuuggau cccgaggaag cacgcgacug gcuguauuuc      420

gagaaauuua agaugaaaau ccacuccgcc accgaucuca cgcugaagac ucagcuggaa      480

gccgugaacg gcaagaccau gccagcacuc gaggucuucg cccaugcgcu gagguuuuuc      540

cgggagcacg ccuugcagga acugcgcgag cagagccccu cccucccaga aaaagacacu      600

gugagguggg uacugaccgu gcccgcaauu uggaagcaac cagccaaaca guuuaugcgg      660

gaggcagccu accuggccgg guuggucagu cgcgaaaaug cggagcagcu ccugaucgca      720

cuggagccgg aagccgccag cguguauugc aggaagcucc ggcugcacca guugcuggau      780

cucuccggcc gcgcacccgg ugggggcagg cugggcgagc ggcgcagcau cgacaguucc      840

uucaggcaag cccgggaaca gcugcgcagg agccggcaua guaggaccuu cuugguggag      900

uccggggucg gugaacucug ggcggagaug caggccggcg aucgcuacgu gguagcagac      960

ugugggggcg guacggugga ucugacuguc caccaacugg agcagccaca uggcacccuc     1020

aaagaacugu acaaggccag cgggggcccc uauggggcag ugggugugga cuuggccuuu     1080

gagcagcugc ucugccggau uuucggcgaa gacuuuaucg ccacuuucaa aaggcagcgc     1140

ccagcagccu gggucgaucu gaccauugcg uuugaggccc ggaagaggac cgcagggccc     1200

caccgcgccg gcgcccugaa caucagcuug ccguucuccu uuauugacuu cuaccggaag     1260

caaagggguc acaaugugga aacugcacuc cggcgcagua gcguaaacuu ugugaaaugg     1320

uccagccagg gcaugcugag gaugaguugu gaggcgauga augagcuguu ccagccaacg     1380

gucuccggga ucauucagca uaucgaagcc cuccuggcac ggcccgaggu gcaaggcguc     1440

aaguugcugu uucucguagg gggcuucgcc gaaagcgccg ugcugcagca cgcagugcag     1500

gccgcgcugg gugcccgcgg guugagggug gucgugcccc augaugucgg ccugaccauc     1560

cucaaaggug cagugcuguu uggccaggcc ccaggggugg uacgggugcg caggaguccc     1620

cucacuuaug gcgucggggu gcugaaccgg uucgucccag gcaggcaccc gcccgagaag     1680

uugcuggugc gcgacggucg gagguggugc accgaugugu ucgagcgcuu uguagccgca     1740

gaacaauccg ucgcccucgg ggaggaagug cggaggagcu acuguccagc gcgccccggc     1800

cagcggaggg ugcugauuaa ucuguauugc ugugccgcag aggacgcccg cuucaucacc     1860

gauccaggcg uccggaaaug cggggcauug ucccuggaac ucgagcccgc cgacugcggu     1920

caggauacug cgggcgcccc gccagggagg cgcgagauuc gggcagccau gcaguuuggc     1980

gacacggaaa ucaaggugac cgccguggau guaagcacua acaggagugu ccgcgcaucc     2040

auugacuucc ugagcaauug a                                               2061


<210>  855
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  855
auggccaggg agaugaccau ccugggcagc gcagugcuca cucuguugcu ggccggguac       60

cucgcgcagc aauaucugcc cuugccaacc ccgaagguca uugguaucga ccugggcacg      120

acuuacugcu ccgugggggu auucuuuccc ggcaccggua aagugaaggu cauuccagau      180

gaaaacgggc acaucaguau ucccagcaug guguccuuca ccgacaauga uguguauguc      240

ggcuacgaga guguggaacu cgccgacagc aacccacaga auacuaucua ugaugcaaaa      300

cgguuuaucg gcaagauuuu caccgccgag gaacuggagg cagagaucgg gcgcuacccc      360

uuuaaaguac ugaacaagaa ugguauggug gaguucuccg ucacgagcaa cgaaacuauu      420

accguguccc cagaauaugu gggcaguagg cuccuguuga agcugaaaga gauggccgag      480

gcguaccucg ggaugccggu cgccaaugca gugaucagcg uacccgccga auuugaccug      540

aagcagcgga acuccacuau ugaggccgca aaucuggccg gcuugaaaau ccuccgcgug      600

auuaacgaac caaccgcggc cgcaauggcc uacggucugc auaaggcaga ugucuuccac      660

gugcugguga ucgaccucgg gggcggcacc cuggauguca gcuugcugaa uaaacaaggg      720

gguauguuuc ucacgagggc caugaguggc aacaauaagc ucgggggcca ggacuucaac      780

cagcggcugu ugcaguaucu cuacaaacag aucuaucaaa cuuacgguuu ugugcccucc      840

cgcaaggagg aaauucauag gcugcggcag gccguagaga uggugaagcu gaaucucacc      900

cugcaccaga gcgcgcaguu guccguccug cucacugugg aggaacaaga ucgcaaagag      960

ccacauagua gcgacaccga acugcccaag gauaaacugu ccagcgcaga cgaccacagg     1020

gucaacagug gcuucgggcg gggcuugucc gauaagaaaa gcggggagag ucaggugcug     1080

uucgaaaccg agaucucccg caagcuguuu gacacucuga acgaggaucu cuuccagaag     1140

auucuggugc cgauccaaca gguauugaaa gaaggucacc uggagaagac ggaaauugac     1200

gagguggucc ucgugggcgg gagcaccagg aucccccgga uccgccaggu cauucaggaa     1260

uuuuucggca aagauccaaa uacuagcgug gaccccgauc uggccguggu aaccggugug     1320

gccauccaag caggcauuga cgggggcucc uggccacugc aggucagugc cuuggagauc     1380

cccaacaagc aucugcagaa aaccaauuuu aacuga                               1416


<210>  856
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  856
auggccgcaa ucggcgugca ccuggggugc accagcgccu gugucgcggu guacaaggac       60

gguagggccg gcguaguggc aaacgaugcc ggggaccggg ucacucccgc agugguggcc      120

uauuccgaga augaagagau ugucggccuc gcggccaaac agagucgcau caggaacauu      180

agcaauaccg ugaugaaggu aaaacaaauc cugggucggu ccaguagcga uccacaggca      240

cagaaguaca uugccgaauc caaaugcuug gugaucgaga agaacgggaa gcugcgcuau      300

gaaaucgaca cgggcgagga gacuaaauuc gucaauccgg aagauguggc caggcucauu      360

uuuagcaaga ugaaagagac cgcacauucc gugcugggca gugacgccaa cgaugucgug      420

aucaccguac ccuucgacuu uggggaaaag cagaaaaaug cguuggguga ggccgcacgg      480

gccgcaggcu ucaacgugcu gcgccucauu cacgagccaa gcgccgcccu gcuggcguac      540

gggaucggcc aagauucccc cacugguaag agcaauauuc ucgucuuuaa acugggcggg      600

accaguuugu cccugagcgu gauggaagug aacuccggca ucuauagggu ccucaguacg      660

aauacugacg auaacauugg gggugcacau uucaccgaga cucuggccca guaccuggcc      720

agcgaauuuc agcgguccuu caagcacgac gugcgcggca augcaagggc caugaugaag      780

uugaccaaca gcgcggaggu agccaaacau agucucucca cccuggggag cgcaaauugu      840

uuucuggaua gucucuauga aggccaggac uucgacugca acgugucccg ggcccgcuuu      900

gagcuguugu guagcccacu guucaacaag ugcaucgagg caaucagggg ucuccuggau      960

caaaauggcu ucacggccga cgauauuaac aaagucgugc uguguggggg cagcucccgg     1020

auccccaagu ugcagcagcu cauuaaagac cuguuuccag ccgucgaacu gcucaauagu     1080

aucccgcccg augaggugau uccaaucggg gcagccaucg aagcggguau ucugaucggc     1140

aaggagaacu ugcuggugga agacagccuc augauugagu gcuccgcccg cgauauccug     1200

guaaaggggg uggacgagag cggcgcaagu agguucacug uccuguuucc cuccgguacc     1260

ccauugcccg cccggcgcca gcacacucuc caagccccgg gcagcauuuc cagugugugu     1320

cuggaacugu acgagagcga ugggaaaaau uccgcaaagg aagagaccaa auucgcgcag     1380

gucgugcucc aggaccugga uaagaaagaa aacggcuuga gggacauccu ggccgugcuc     1440

accaugaagc gggacgggag ccugcacgua acuugcacgg aucaagagac cggcaagugc     1500

gaggcaauca guauugaaau cgccuccuga                                      1530


<210>  857
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  857
augagcgugg ucggccugga cguggggucc cagaguugcu acaucgccgu agcaagggcc       60

gguggcauug aaaccaucgc gaacgaguuc agcgaucggu guacucccuc cgugauuagu      120

uuugggagca agaaucgcac caucggcguc gccgccaaaa accaacagau uacgcacgca      180

aauaacacug uguccaauuu caagagguuu cauggucggg cauucaacga cccauuuauc      240

cagaaagaga aggaaaaucu cagcuaugau cuggugccgu ugaaaaacgg gggcgucggc      300

aucaagguga uguacauggg ggaggaacac cuguucuccg uagagcagau uaccgccaug      360

cuccugacca aguugaaaga gacugcggaa aauagucuga agaaacccgu gaccgacugc      420

gucaucagcg ugccauccuu uuucacggau gccgagcgca ggagcgugcu cgacgcagcc      480

caaauugucg gucugaacug ucugcggcuc augaaugaua ugacugccgu ggcacugaac      540

uauggcaucu acaagcagga cuugcccagu cuggaugaaa aaccacgcau uguaguguuu      600

gucgacaugg ggcauuccgc cuuccaggug agcgcgugcg ccuuuaauaa gggcaaacuc      660

aaggugcugg guaccgcauu cgaucccuuc cugggcggga agaacuuuga cgagaaauug      720

gucgagcacu ucugugccga auuuaagacu aaauauaagc ucgaugcaaa auccaagauc      780

agggcccugc ugcggcucua ccaggagugc gaaaagcuga aaaaguugau gaguagcaau      840

uccaccgacc ugccacucaa cauugagugu uucaugaacg acaaagaugu gagcggcaag      900

augaaucgca gucaauuuga agaacugugc gccgagcugu ugcagaaaau cgaaguaccg      960

cucuauuccc ugcuggagca gacccaucuc aagguggaag acgucagcgc gguggagauc     1020

gucgggggug caacgaggau ucccgccgug aaggaacgga ucgccaaauu cuuuggcaag     1080

gauauuagua cuacccugaa cgcagacgag gccguggcgc gcgggugugc cuugcagugc     1140

gcaauccugu ccccagccuu caaaguaagg gaguuuagcg ugacugaugc aguccccuuc     1200

ccaauuagcc ucaucuggaa ucacgacucc gaagauaccg agggcgugca cgaagucuuu     1260

agucggaacc augccgcccc cuucagcaag gugcugaccu uucugcgcag ggguccguuc     1320

gaguuggaag cauucuacuc cgacccccaa ggcgugccau accccgaggc caaaaucggg     1380

cgguuuguag ugcagaaugu cagcgcgcag aaggauggcg agaagagucg cgugaaaguc     1440

aaggugaggg ugaacacuca cgggauuuuc acgaucucca ccgccagcau gguagaaaaa     1500

gucccaacug aggaaaauga gauguccagu gaggcagaca uggaaugccu caaccaacgg     1560

cccccagaga auccggauac cgacaagaac gugcagcagg acaauagcga agccgguacc     1620

cagccccaag ugcagacuga ugcccagcag acgucccaaa gcccacccag uccagagcug     1680

accuccgaag agaacaaaau ucccgacgca gauaaggcga augagaaaaa ggucgaccag     1740

ccgccagaag ccaagaaacc caagaucaaa guggugaacg uagagcugcc cauugaagca     1800

aaucucgucu ggcagcuggg caaggauuug cugaacaugu auaucgagac ugaagggaaa     1860

augaucaugc aggacaagcu cgagaaggag aggaacgaug ccaaaaaugc cguggaagag     1920

uacguguaug aauuucgcga caagcugugu ggcccauacg agaaauucau uugcgaacaa     1980

gaucaucaga acuuucugcg guugcugacc gagaccgagg acuggcucua ugaagagggu     2040

gaagaucagg caaagcaggc cuacgucgac aaacuggagg agcucaugaa gaucggcacu     2100

cccgugaagg uaagguucca agaagcggag gaacgcccaa aaauguuuga ggaacugggg     2160

cagcgguugc agcacuaugc caagauugca gccgauuuca ggaauaaaga cgagaaguac     2220

aaccacaucg acgagagcga aaugaaaaag guggagaaau ccgucaauga agugauggag     2280

uggaugaaca augugaugaa cgcccaagca aagaagaguc uggaucagga cccggucgug     2340

cgcgcccagg aaauuaaaac gaagaucaaa gagcucaaua acaccuguga gcccguagug     2400

acucagccaa agcccaaaau ugaaagccca aagcuggagc ggacccccaa uggcccgaac     2460

aucgauaaga aagaagagga ccuggaggau aagaauaacu uuggggcgga accaccccau     2520

caaaauggcg agugcuaccc aaacgagaaa aacuccguca auauggacuu ggauuga        2577


<210>  858
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  858
auggccgaca aggugaggcg gcagcgcccc aggcggcgcg ucugcugggc acugguggcc       60

guacuccugg cggauuugcu ggcccucagc gacacccugg cagugauguc cgucgauuug      120

ggcagugaga gcaugaaagu ggccaucgug aagccagggg ucccgaugga aauugugcug      180

aacaaagagu ccaggcggaa gacucccgua aucgugaccc ucaaagaaaa ugagcgcuuc      240

uuuggugaca gugcagccag cauggcgauu aagaacccaa aggccacgcu gagguacuuc      300

caacaucugc ucggcaaaca ggcagauaau ccccacgucg cccuguauca ggcccgguuu      360

ccagaacacg aguugacuuu cgacccccag cgccaaaccg ugcauuuuca gaucuccagc      420

cagcugcagu ucuccccaga ggaagugcuc gggauggucc ugaacuacag uaggagccug      480

gcagaggauu uugccgaaca accgauuaag gacgcgguga ucaccguacc cguguucuuu      540

aaucaggccg agcggcgcgc agucuugcag gccgcaagga uggccggccu caaagugcug      600

cagcugauca acgauaauac ugccaccgcg cucuccuaug guguguuccg gcgcaaggac      660

auuaacacga cugcacaaaa uaucauguuu uacgauaugg ggagcggcag uaccgucugu      720

acuauuguga ccuaucagau gguaaaaacc aaggaggccg gcaugcagcc acaacugcag      780

aucaggggug ugggguucga ccggacguug ggcgggcugg aaauggagcu ccgccugagg      840

gaacggcugg ccggcuuguu caacgagcag aggaaagguc agcgcgcaaa ggauguccgg      900

gaaaauccca gggccauggc gaagcuccug cgcgaggcca accggcugaa aacugugcuc      960

uccgcaaaug ccgaccacau ggcacaaauu gaggggcuga uggacgaugu cgacuuuaag     1020

gccaaaguga ccagggugga guucgaggaa uugugcgccg aucuguuuga gcgcguacca     1080

ggccccgugc agcaggcacu ccagagcgcc gaaauguccc uggacgagau cgagcaaguc     1140

auucuggugg gcggggcgac ucgggucccg agggugcagg aaguguugcu caaggccgua     1200

gguaaagagg aacugggcaa gaacaucaau gcagaugagg ccgccgcaau gggggcggug     1260

uaccaggccg cagcccugag uaaggccuuc aaagucaagc ccuuuguggu ccgggacgca     1320

gugguguauc caauccucgu agaguucacc cgcgaggucg aggaagaacc cggcauucau     1380

agccugaaac acaacaagag gguguuguuu ucccggaugg guccauaccc ccagcgcaaa     1440

gugaucaccu ucaacaggua cagccacgau uuuaauuucc auauuaacua uggcgaccug     1500

ggguuucucg gcccagaaga ucugcggguc uucgggaguc aaaaucugac uacggugaag     1560

uugaagggug ugggcgacuc cuuuaaaaag uacccggauu augagagcaa agggaucaag     1620

gcccacuuca accuggacga gaguggcgua cucucccugg accgcgucga aagcguguuc     1680

gagacccucg uggaagauag cgcggaggaa gaguccacuc ugaccaaauu ggguaauacc     1740

auuaguagcc uguuuggcgg gggcacuacg cccgacgcca aggagaacgg gaccgauacu     1800

guccaggaag aggaagaguc cccagcagaa ggcagcaagg acgagcccgg ugaacaggug     1860

gaacucaaag aggaagccga ggccccagua gaagauggga gucagccccc gccacccgag     1920

cccaagggcg acgcaacccc agagggugaa aaagccaccg agaaggaaaa uggcgauaaa     1980

uccgaggcgc aaaagcccag cgagaaagcc gaagcagggc cagagggcgu ggccccggca     2040

cccgaagggg agaagaagca gaaaccagcc aggaagcgga ggauggucga agagaucggc     2100

guggagcugg ugguccugga cuugcccgau cugccagaag acaaacucgc gcaguccgug     2160

caaaagcugc aggaucucac ucugcgcgac uuggagaaac aggaacggga gaaggccgca     2220

aacagucugg aagccuucau cuuugagacg caggauaagc uguaccaacc cgaguaucag     2280

gaaguaagca ccgaggaaca gagggaggag auuuccggua aacucagcgc cgcaaguacu     2340

uggcuggaag acgagggggu gggcgccacc acugucaugu ugaaggaaaa acuggcggag     2400

cuccgcaagc ugugucaggg ccucuucuuu cggguggaag agaggaaaaa guggccggag     2460

cgccuguccg ccuuggacaa ucugcugaac cauagcucca uguuccucaa gggggcacgg     2520

cugaucccag aaauggauca aauuuuuacc gagguggaaa ugacgaccuu ggagaaaguc     2580

aucaaugaaa cuugggccug gaagaacgca acccuggccg agcaggccaa acuccccgca     2640

acugagaagc cagugcugcu gaguaaagac auugaagcga agaugauggc ccucgauagg     2700

gagguacagu accuguugaa uaaagccaag uucaccaagc cccgcccgcg gcccaaagac     2760

aagaacggua cgagggcaga accaccccug aaugccagcg cauccgauca gggcgagaaa     2820

gugaucccac ccgccgggca aaccgaagac gcggagccaa ucagcgagcc ggaaaagguc     2880

gagacuggca gugaacccgg ugauaccgag ccacucgagc ugggcgggcc cggcgccgaa     2940

ccagagcaga aagaacaguc cacugggcaa aagcgccccu ugaagaacga cgagcuguga     3000


<210>  859
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  859
augcccgagg aaacccagac ucaagaccag ccaauggagg aagaggaagu ggagaccuuc       60

gccuuucagg cagagaucgc ccagcugaug agccucauua ucaacacguu cuacuccaau      120

aaggaaauuu uucugaggga guugaucagu aacagcuccg augcgcugga caaaauucgg      180

uaugaaaguc ucacugaucc gagcaagcug gacuccggca aagaguugca caucaaucug      240

auccccaaca agcaagaucg cacccucacc auugucgaca cugggaucgg uaugaccaaa      300

gccgaucuga uuaauaaccu gggcacgauc gcaaagagcg ggacuaaggc cuucauggag      360

gcacuccagg ccggcgcgga cauuuccaug aucggucagu uugggguggg cuucuacagu      420

gccuaucugg uagcagaaaa agugaccguc auuacuaagc auaaugauga cgagcaguac      480

gccugggaaa gcuccgccgg cgggagcuuu accgugagga ccgauacggg ugagccaaug      540

ggccggggga cuaaagugau cuugcaccug aaggaagacc aaaccgagua ucucgaggaa      600

cgcaggauca aagagauugu caagaaacau agucaguuca ucggcuaccc cauuacucug      660

uuuguggaaa aggagcggga uaaggaagua uccgacgacg aggcagagga aaaagaggau      720

aaggaagagg aaaaagagaa ggaggaaaaa gagagcgaag acaagccaga gaucgaggau      780

guggguuccg acgaagagga agagaagaaa gauggggaca agaaaaagaa aaagaagauu      840

aaagaaaagu auaucgauca ggaggagcug aacaaaacca agcccaucug gacccgcaau      900

ccagacgaua uuacuaacga agaguacggc gaguucuaca aaaguuugac gaaugacugg      960

gaggaucacc ucgccgucaa gcauuuuagc guggaaggcc agcuggaguu cagggcgcuc     1020

cuguucgugc cgcggcgcgc ccccuuugac cuguucgaga acaggaagaa aaagaauaac     1080

aucaaauugu auguccggcg cguguuuauu auggacaauu gcgaagaacu gaucccagaa     1140

uaccucaacu ucauuagggg uguaguggau uccgaggacc ugccccugaa caucagccgg     1200

gaaauguugc aacagaguaa gauccucaaa gucauucgca agaaucuggu gaaaaagugu     1260

cuggagcucu uuaccgagcu ggcagaagau aaggagaacu auaaaaaguu cuacgaacag     1320

uuuuccaaaa auaucaaguu ggggauucac gaggacagcc aaaacaggaa aaagcugagu     1380

gagcuccugc gguauuacac uuccgccagc ggcgaugaaa uggugagccu gaaggacuau     1440

ugcacccgca ugaaagagaa ucagaagcac aucuacuaca uuaccgggga aacuaaagau     1500

caggucgcaa acuccgccuu cguggagagg uugcggaagc auggccucga aguaaucuau     1560

augauugagc caaucgacga guacugugug cagcaacuga aagaauuuga ggguaagacg     1620

cuggucagug ugaccaagga aggccucgag cugcccgaag augaggagga gaaaaagaaa     1680

caggaagaaa agaaaacuaa guucgagaau uugugcaaaa ucaugaagga cauucuggag     1740

aagaaagucg aaaagguggu gguaagcaac aggcucguga ccuccccgug uugcaucguc     1800

accagcacuu auggguggac ggccaauaug gagcgcauua ugaaagcgca ggcacugcgg     1860

gauaacagua ccaugggcua cauggccgcc aagaaacacc uggaaaucaa ucccgaccau     1920

uccauuaucg agacuuugag gcagaaggca gaagccgaua agaacgacaa aagcgugaag     1980

gaccugguca uccuccugua ugagaccgcg cuccugucca guggguuuag cuuggaggau     2040

ccacaaacuc acgccaaucg cauuuaccgg augaucaaac ugggucucgg cauugacgaa     2100

gaugacccca ccgcagauga cacguccgcc gcagugaccg aggaaaugcc accccuggag     2160

ggggaugacg auacuagcag gauggaagag guggacuga                            2199


<210>  860
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  860
auggacagcu ccaagcugga uaguggcaaa gggcuccaca ucaaccuggu gcccaauaag       60

cagaaccaaa ccuugacuau ugucgacacc aggaucggua ugacgaaaac ugaucugauu      120

aauaaccucg gcaccgugac caagagcggg acuaaagccu ucauggaggc acugcaggcc      180

gacgcggaua ucuccaugau uggccauuuu gguguagggu ucuacagugc cuauuuggug      240

gcaaagaagg ucaccgugau cagcaaacac aauaacgacg aacaguacac gugggagucc      300

agcgccggcg gcuccuuuac ugugcggacc gaugaauga                             339


<210>  861
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  861
augcccgagg aagugcacca uggcgaggaa gaggucgaaa ccuucgccuu ucaggcagag       60

aucgcccaac ugaugagccu cauuaucaac acuuucuacu ccaauaagga gauuuuucug      120

agggaauuga ucaguaacgc gagcgacgcc cuggauaaaa uucgguauga gucccucacc      180

gacccaagua agcuggauag cgggaaagaa uugaagaucg acaucauucc gaauccccag      240

gagcgcacgc ugacucucgu ggauaccggu aucggcauga ccaaagcaga ccugauuaac      300

aaucugggga cuaucgccaa guccggcacc aaggcauuca uggaggcccu ccaggcgggu      360

gccgauauua gcaugaucgg gcaguuuggc guaggcuucu acuccgcaua ucugguggcc      420

gaaaaagucg uggugauuac gaagcacaac gacgaugagc aauacgccug ggaaaguagc      480

gcaggggguu ccuuuacugu cagggccgac cauggcgagc caaucgggcg gggcaccaaa      540

gugaucuugc accugaagga agaucagacu gaguaucucg aggaacgcag gguaaaagag      600

guggucaaga aacauagcca guucauuggu uaccccauca cccuguaucu ggaaaaggag      660

cgggaaaagg agauuaguga cgaugaggcg gaagaggaaa aaggggagaa ggaagaggag      720

gacaaagacg augaagagaa gccaaaaauc gaagacgugg gcuccgauga ggaggacgau      780

agcggcaagg acaagaaaaa gaaaaccaag aaaauuaagg aaaaguacau cgaucaggag      840

gaauugaaua aaacgaagcc caucuggacu cgcaacccag acgauauuac ccaagaggaa      900

uacggggagu uuuauaaauc ccucacuaau gacugggagg aucaccuggc cgugaagcac      960

uucagugucg aaggucagcu ggaguuuagg gcacuccugu ucaucccgcg gcgcgccccc     1020

uucgacuugu uugaaaacaa aaagaagaaa aauaacauua agcuguacgu gaggcgggua     1080

uucaucaugg acagcugcga ugagcucauu ccagaauauc ugaauuuuau ccgcggcgug     1140

gucgacuccg aggaucugcc cuugaacauc agcagggaga ugcuccagca gaguaaaauu     1200

cugaagguga uccggaaaaa uauugugaag aaaugucugg aacucuucuc cgagcuggca     1260

gaagacaagg agaacuacaa gaaauuuuau gaagccuuca gcaagaacuu gaaacugggg     1320

auccaugagg auaguaccaa ucgcaggcgg cucuccgagc ugcugcgcua ccacaccagc     1380

caaagcggcg acgaaaugac uuccuugagu gaguauguca gcaggaugaa ggaaacgcag     1440

aaauccauuu acuacaucac cggugagagc aaggaacagg uggccaacag ugcguuugua     1500

gagcggguga ggaagcgcgg cuucgagguc guguauauga cugaaccaau ugaugaguac     1560

ugcguccaac agcucaaaga auuugacggg aagucccugg ugagcgugac caaagagggc     1620

cuggagcucc ccgaagauga ggaagagaag aaaaagaugg aagaguccaa ggcaaaauuc     1680

gagaaucugu guaaguugau gaaagaaauc cuggacaaga aaguagagaa ggugaccauc     1740

aguaaccggc ucgucagcuc cccgugcugu auugugacua gcacguaugg guggaccgcc     1800

aauauggaaa ggaucaugaa agcccaggca cugcgcgaua acaguacuau ggguuacaug     1860

auggccaaga agcaucugga gauuaauccc gaccacccaa ucgucgagac cuugcggcag     1920

aaagcggaag ccgauaagaa cgacaaagca gugaaggacc uggugguacu ccuguuugag     1980

accgcccucc uguccagcgg cuucuccuug gaagaucccc aaacucacag uaauaggauu     2040

uaucgcauga ucaaacuggg gcucggcauc gacgaggaug aaguggcagc cgaggagcca     2100

aacgccgcag uccccgacga aauuccaccg cuggagggug augaagacgc cagccggaug     2160

gaggaagugg auuga                                                      2175


<210>  862
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  862
augagggccc ugugggugcu cggccugugc ugugucuugc ugaccuucgg gagcgugcgg       60

gcagacgaug agguagacgu ggaugguacu gucgaagagg accucggcaa gucccgcgaa      120

gggaguagga ccgaugacga gguggugcag cgggaagagg aggccaucca acuggauggc      180

uugaacgcga gccagauucg cgaacugagg gagaaauccg aaaaguuugc cuuccaggca      240

gaggucaauc ggaugaugaa acucaucauu aacagucugu acaagaauaa agagaucuuu      300

cugcgcgaac ucauuagcaa cgccuccgac gcacuggaua agaucagguu gaucagccug      360

acggacgaga augcccucuc cgguaacgaa gaacugacug ugaagauuaa augcgauaag      420

gagaaaaauc uguugcacgu aaccgacacc ggggugggca ugacucggga ggagcucguc      480

aagaaccugg gcaccaucgc gaaaaguggg acgagcgagu uccugaauaa gaugacugag      540

gcccaggaag auggucaauc caccagcgag cucauuggcc aguuuggggu gggcuucuau      600

agugcauuuc ugguggccga caaagucauc gugacuucca agcauaacaa ugacacccag      660

cacauuuggg aaagcgauuc caacgaguuc aguguaaucg ccgacccccg cgguaauacc      720

uuggggaggg gcacgacuau uacccuggug cucaaggagg aagcaagcga uuaccuggag      780

cuggacacua ucaaaaacuu ggucaagaaa uauucccagu uuaucaauuu cccaauuuac      840

guguggagca guaagaccga aaccguggag gaaccgaugg aggaggaaga ggccgcgaaa      900

gaagagaagg aggaauccga ugacgaggcc gcagucgaag aggaagagga ggaaaagaaa      960

cccaagacua aaaaggugga gaaaacggua ugggauuggg aacucaugaa cgacaucaag     1020

ccaauuuggc aacggcccag caaggaggug gaagaggaug aguauaaagc cuuuuacaag     1080

aguuucucca aagaaagcga cgauccaaug gcauauaucc auuucaccgc cgagggcgaa     1140

gucacuuuua agagcauucu guucgugccc accuccgccc cacgcgggcu guuugacgag     1200

uacgguagua aaaagagcga cuacaucaag cucuauguca ggcggguguu caucaccgau     1260

gacuuucacg auaugaugcc gaaauaccug aacuucguga agggcguagu ggacuccgau     1320

gacuugcccc ugaaugucag ccgcgaaacu cuccagcagc auaaacugcu gaaggugauu     1380

aggaaaaagu ugguccggaa aacgcucgau augaucaaga agauugcgga cgauaaauau     1440

aacgacaccu uuuggaagga guucgggacu aauaucaaac ugggcgugau ugaggaucac     1500

aguaaccgca ccaggcuggc aaagcuccug cgguuucagu ccagccacca uccaaccgac     1560

aucacuuccu uggaucaaua cguggaaagg augaaagaga agcaggacaa gaucuauuuc     1620

auggccggua guagccgcaa agaagccgag uccagccccu uuguagagcg gcugcucaag     1680

aaaggcuacg aagugauuua ucugacggag ccagucgacg aauacuguau ccaggcacug     1740

cccgaguucg augggaagag guuucaaaau guggccaaag aaggcgucaa guucgacgag     1800

agugagaaga ccaaagaauc ccgcgaggcg guggaaaagg aguucgaacc guugcugaac     1860

uggaugaaag auaaggcccu caaagacaag auugagaaag cagugguaag ccagcggcug     1920

acugaguccc ccugcgcccu cgucgcaagu caguacgggu ggagcgguaa uauggaaagg     1980

aucaugaagg cccaggccua ucaaaccggc aaggauauuu ccacuaacua cuaugcaagc     2040

cagaaaaaga ccuuugagau caauccacgc cacccccuga uucgggacau guugaggcgg     2100

aucaaagaag augaggacga uaagacggug cuggaccucg ccgugguccu guucgagacc     2160

gcgacucugc gcagugggua cuugcugcca gauaccaaag ccuauggcga caggaucgaa     2220

cggaugcucc gccugucccu caacauugac cccgaugcaa agguggagga agaaccagaa     2280

gaggagccgg aagagacugc cgaagacacc acggaggaua ccgaacagga cgaggaugag     2340

gaaauggacg uggguacuga ugaggaagag gaaaccgcca aggagagcac ugcagagaaa     2400

gacgaacugu ga                                                         2412


<210>  863
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  863
auggccaggg agcugcgggc acuccuguug uggggccgca ggcugcggcc ccuccugcgc       60

gccccagcgu uggccgcagu gcccgggggu aagccgaucc ugugcccaag gcggaccacu      120

gcccagcucg gcccccgcag gaacccagca uggagccugc aagccgggcg gcuguucucc      180

acccagacgg cggaagacaa agaggaaccc cuccacagua uuaucagcuc cacugagagu      240

guccagggca gcaccuccaa gcaugaauuu caggccgaga ccaaaaagcu guuggauauu      300

guggcacgca gccuguacuc cgagaaagaa guauucauca gggagcucau uaguaaugcc      360

agcgacgccc uggaaaagcu gcggcacaag uugguguccg auggucaagc acucccagag      420

auggagaucc aucugcagac uaacgccgaa aaagggacca ucacgauuca ggacacuggc      480

aucggcauga cccaggagga acuggucagc aaucucggga cuauugcgcg cagugguucc      540

aaggccuuuc uggaugcauu gcaaaaccag gccgaggcaa gcuccaaaau cauuggccag      600

uucggggugg gcuuuuauag ugccuucaug guggccgaca gggucgaagu guacagccgg      660

uccgcggcac cggguagccu gggguaucag uggcucagug auggcuccgg cguauuugag      720

aucgccgagg ccagcggggu gcgcaccggu accaagauua ucauccaccu gaaaagugac      780

uguaaggagu ucuccagcga ggcaaggguc cgggaugugg ugacgaaaua cagcaauuuu      840

gucuccuucc cccuguauuu gaacggccgc aggaugaaua cucuccaagc cauuuggaug      900

auggacccaa aggaugugcg ggaauggcag caugaggaau uuuacaggua uguagcgcag      960

gcccacgaca agccccgcua cacccugcac uacaaaacug augcaccacu gaacauccgg     1020

aguauuuucu augugcccga caugaagccg agcauguucg acgucuccag ggagcucggg     1080

agcagugugg cccuguacuc ccgcaaagug uugauccaaa ccaaggcaac cgauauucug     1140

cccaaauggc uccgguuuau caggggcguc guggacagcg aggauauccc acugaaucug     1200

ucccgcgaau ugcuccagga gagugcccug auucggaagc ugagggacgu acuccagcag     1260

cggcugauca aguucuuuau ugaucaaagc aaaaaggacg ccgaaaaaua ugcaaaguuc     1320

uuugaggauu acgguuuguu caugcgcgaa ggcaucguga cugccacgga gcaggagguc     1380

aaagaagaca uugcgaagcu gcucagguau gaguccagcg cccugcccag ugggcagcug     1440

accuccuuga gcgaauacgc aucccggaug cgcgccggca cuaggaacau cuauuaccug     1500

ugcgccccaa aucggcaucu cgcagagcac agucccuacu augaggcgau gaagaaaaag     1560

gauaccgaag ugcuguuuug uuucgagcag uuugacgaac ucacccuguu gcaucugcgc     1620

gaguucgaua aaaagaaacu caucagcguc gaaacugaca uuguggugga ccacuacaag     1680

gaggagaagu uugaagauag guccccagcc gcagagugcc ugagcgaaaa agagacggaa     1740

gaacugaugg ccuggaugcg gaacguauug gggaguaggg ugaccaaugu caaggugacu     1800

cugcgccucg acacccaccc ggccaugguc accgugcugg agaugggugc agcccggcau     1860

uuccucagga ugcaacagcu ggcgaaaacu caggaggaac gcgcccaguu gcugcaaccc     1920

acgcuggaaa ucaacccacg gcacgcacuc auuaagaaac ugaaucaguu gagggccucc     1980

gagcccggcc uggcccagcu ccugguggau cagaucuaug aaaacgcaau gauugccgcg     2040

gggcucguag acgauccacg cgccauggug ggccggcuga acgaguugcu ggucaaggca     2100

cuggagaggc auuga                                                      2115


<210>  864
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  864
augggcaaga ucagcucccu gcccacccaa cucuucaaau gcuguuuuug cgacuuccug       60

aaggugaaaa ugcacacuau gaguagcucc cauuuguuuu accuggcccu cugucuguug      120

accuucacga guagcgcaac ugccgggcca gagacccugu gcggugcgga acucgucgau      180

gcccugcagu uugugugugg cgacaggggg uucuauuuua acaagccgac cggcuacggu      240

uccagcuccc ggcgcgcacc ccagacuggg auuguagaug agugcuguuu caggaguugc      300

gaccugcggc gccucgaaau guauugugcc ccacugaaac ccgcaaagag cgccaggucc      360

gugcgggcgc agcgccacac cgauaugcca aagacgcaga aagaggucca uuugaagaau      420

gccagcaggg gcagugcagg caacaaaaau uaccggaugu ga                         462


<210>  865
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  865
augggcaucc ccauggguaa gagcaugcug gugcuccuga ccuucuuggc cuuugcaucc       60

ugcuguauug ccgcguacag gccaagugag acucugugcg ggggcgaacu cgucgacacc      120

cugcaguucg ugugugggga ucggggcuuu uauuucagcc gcccggccuc caggguaagu      180

cggcgcagca gggguaucgu ggaggaaugc uguuuucggu ccugcgacuu ggcacugcuc      240

gagacguacu gugccacucc cgcaaaaagc gaacgcgaug ucuccacccc acccaccgug      300

cugccagaca acuuccccag guauccagug gggaaguuuu uccaauacga uacuuggaaa      360

cagaguaccc agcggcugcg caggggccuc ccggcccugu ugcgggcgcg caggggccac      420

guccuggcca aggagcucga ggcauuucgg gaagccaaac gccauaggcc ccugauugcc      480

cugccaacgc aggaccccgc acacgggggu gccccacccg agauggcgag caaucggaag      540

uga                                                                    543


<210>  866
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  866
augaacagcu ucuccaccag ugccuuuggc cccguggcau ucagccuggg gcuccuguug       60

guccugccag ccgcguuucc ggcccccgug ccacccggug aggacuccaa ggauguagca      120

gccccacaca ggcagccccu caccaguagc gaacggaucg acaaacaaau ucgcuacauc      180

cuggauggca uuuccgcauu gaggaaggag acuugcaaua aaagcaacau gugugaaucc      240

aguaaggagg cccuggcgga aaauaaccuc aaucugccaa aaauggccga gaaggacggg      300

ugcuuccaga gcggcuuuaa cgaggaaacg ugucugguga agaucauuac uggucuccug      360

gaguucgaag ucuauuugga guaccugcag aaucgguuug aguccagcga agaacaggca      420

cgcgccgugc aaaugaguac caaagugcuc auccaguucc ugcagaagaa agccaagaac      480

cuggaugcaa ucaccacucc ggaccccacc acgaaugccu ccuugcucac uaaacugcag      540

gcgcaaaacc aguggcugca ggauaugacc acucaucuca uucugaggag cuuuaaggag      600

uucuugcagu ccagucugcg ggcccuccgc caaauguga                             639


<210>  867
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  867
augccccugc ucuggcugag gggcuucuug cuggccagcu gcuggaucau ugugcggucc       60

aguccaaccc cggggagcga gggucacucc gcagcccccg acuguccaag uugcgcgcuc      120

gccgcacugc ccaaggaugu cccaaacagc cagcccgaaa ugguggaggc cgugaaaaag      180

cauaucuuga auaugcugca ccucaaaaag cgcccagacg uaacucaacc gguccccaaa      240

gcagcccugc ugaacgcgau uaggaagcuc caugugggca agguggggga aaauggcuac      300

gucgagaucg aagaugacau uggucggcgc gccgagauga acgagcugau ggaacagacc      360

uccgagauca ucacguuugc agaaagcggg acugccagga aaaccuugca cuucgagauu      420

uccaaggagg gcagugaucu gagcguggua gaacgggccg agguguggcu cuuucugaaa      480

gucccaaagg caaaucgcac caggacuaaa gugaccaucc ggcuguucca gcagcaaaag      540

cauccccagg gcuccuugga cacgggggaa gaggccgaag aggugggucu caaaggcgag      600

cgcagcgaac ugcugcucag ugagaagguc guggaugcga ggaaguccac uuggcacgua      660

uuuccaguga gcuccaguau ucagcggcug uuggaccagg ggaaaagcuc ccuggauguc      720

cgcaucgccu gugaacaaug ccaggagagc ggcgcaaguc ucgugcugcu ggguaagaaa      780

aagaaaaagg aagaggaggg ggaaggcaag aaaaagggcg ggggugaggg cggggccggc      840

gcagacgaag agaaagaaca gucccacagg cccuucuuga ugcuccaggc ccggcaaagc      900

gaggaucauc cgcaccgcag gcggcgcagg ggucuggagu gugacggcaa ggugaacauu      960

ugcuguaaaa agcaguuuuu cgucaguuuu aaggauaucg gguggaauga cuggauuauc     1020

gcccccuccg gcuaucaugc gaacuacugc gaaggggagu guccaagcca caucgcaggu     1080

accagcggcu ccagucugag cuuccacucc acugugauua aucauuaucg gaugaggggg     1140

cacagccccu uugccaaccu caaaaguugc ugcguaccaa ccaagcugcg ccccaugucc     1200

auguuguacu augacgaugg ccagaauauc auuaaaaagg acauccaaaa caugauugug     1260

gaagagugug guugcagcug a                                               1281


<210>  868
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  868
auggacggcc ugcccgggag ggcccucggu gcagccugcc uguugcugcu cgcggccggc       60

uggcuggggc cagaggcaug gggcagcccg acucccccac ccaccccagc cgcaccccca      120

ccgcccccac ccccagguuc ccccgggggc agucaggaua ccuguacgag cugcggcggg      180

uuccggcgcc cggaagaguu ggguagggug gacggcgauu uucuggaagc cgucaagcgg      240

cacauccucu cccgccugca aaugaggggg cggcccaaca uuacucaugc ggugccaaaa      300

gccgcaaugg uaaccgcccu gcgcaagcuc cacgccggca aagugaggga ggacggucgg      360

gucgaaaucc cccaucugga ugggcacgca aguccaggcg ccgacggcca ggagcgcgug      420

agcgagauua ucuccuucgc ggaaaccgau ggguuggcca gcuccagggu gcggcuguac      480

uuuuucauua guaaugaggg uaaccagaau cucuuugucg ugcaggcaag ccuguggcug      540

uauuugaagc uccugcccua cguacuggaa aaaggcuccc gcaggaaggu gcgggucaag      600

guguauuucc aagagcaggg gcauggcgac cgcuggaaca ugguggagaa aagggucgau      660

cucaagcgga gcgguuggca cacuuuucca cugaccgaag ccauccaggc auuguucgag      720

cgcggcgaaa ggcggcugaa ucucgacgug cagugugaua guugccaaga gcuggccgua      780

gugccggucu uuguggaccc cggggaagag ucccacaggc cauucguggu cgugcaggcc      840

cgccugggcg auagccggca uaggauccgc aaacgggggu uggaguguga cgguaggacg      900

aaccucugcu gucgccagca guuuuucauu gacuuccggc ugaucggcug gaaugauugg      960

auuaucgcgc ccacugggua cuauggcaac uacugcgaag guuccugucc agcauaucug     1020

gccggcguac ccgggagugc cagcuccuuu cacaccgcag uggucaauca auacaggaug     1080

cggggccuca acccggggac ugugaauagc ugcugcauuc caaccaagcu gaguaccaug     1140

uccauguugu acuucgacga ugaguauaac aucgucaaac gcgacgugcc caauaugauu     1200

guggaagagu guggcugcgc cuga                                            1224


<210>  869
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  869
auggcccuga gggugcuccu guugaccgca cugacucucu gccacggcuu caaccuggac       60

accgagaaug ccaugacguu ucaggaaaac gcgcgggggu ucggucaaag cgucgugcag      120

uugcagggcu cccgcguagu ggucggggcg ccccaggaga ucguggcagc caaucaaagg      180

ggcagucugu accaguguga uuauagcacu gguuccugcg aaccaauucg gcuccaggug      240

ccggucgagg cagugaacau gagucugggg cugagccucg ccgcgaccac cuccccaccc      300

cagcuguugg ccuguggccc cacuguacau caaaccugca gcgaaaauac guacgugaag      360

ggccuguguu uucucuucgg guccaaccug cgccagcagc cacagaaauu ucccgaggca      420

cugagggguu gcccacaaga ggacagugau aucgccuucu ugauugacgg cagcgggucc      480

aucauuccgc acgauuuucg gcgcaugaag gaguucguca gcacugugau ggaacagcuc      540

aaaaagagua aaacccuguu uucccugaug caguauagcg aagaguucag gauccauuuu      600

acuuucaagg aguuccaaaa uaaccccaau ccacgguccc ucgugaagcc caucacccag      660

cuguugggcc gcacccacac ggccacuggu auuaggaaag ucgugcggga acuguuuaac      720

aucaccaaug gggcacgcaa gaacgccuuc aaaauucucg uagugaucac ugacggcgag      780

aaguuuggcg auccacuggg guacgaagac gucauucccg aggcggauag ggaaggugug      840

auccgguaug ugauuggcgu cggggacgcc uuccgcagug agaaaagcag gcaggagcug      900

aauaccaucg cauccaagcc gccccgggau cauguguuuc agguaaacaa uuucgaagcc      960

uugaaaacca uccaaaacca gcuccgcgag aagauuuuug caaucgaagg cacucagacg     1020

gguagcaguu ccagcuucga gcacgaaaug agucaggagg gcuuuuccgc cgccauuacc     1080

agcaacgggc cacugcugag cacugugggc uccuacgacu gggccggggg ugucuuccuc     1140

uauaccagua aggagaaaag caccuuuauc aauaugacua ggguggauuc cgacaugaac     1200

gacgcauacc ugggcuacgc cgccgcaauu aucuugcgga auagggucca aagccuggug     1260

cucggggcgc cccgcuauca gcacaucggc cugguggcca uguuccggca gaacacgggu     1320

augugggaaa guaaugccaa cguaaagggc acccagauug gggcauacuu uggcgccucc     1380

cuguguagcg uggaugucga cuccaauggg aguacugauu uggugcucau cggcgcacca     1440

cauuauuacg agcaaaccag gggugggcag gucagcgugu gcccccugcc acgcggccgg     1500

gccagguggc agugugacgc cgugcuguau ggugaacagg gccaaccgug ggggcgcuuc     1560

ggcgcagccc ucaccguacu gggggaugug aacggcgaca aauugacuga ugucgcgauu     1620

ggugcccccg gggaggaaga caaucggggc gcaguguacc uguuccacgg cacguccggg     1680

agcgguauca guccauccca uagccagagg auugccggcu ccaagcucag uccccggcug     1740

caguauuuug ggcaaagccu guccggcggu caggauuuga ccauggacgg gcuggucgau     1800

cucacugugg gcgcccaggg ccacgugcug cuccugcgca gccagccagu auugaggguc     1860

aaagcaauca uggaguucaa cccccgggag guggcgcgca auguguuuga augcaacgac     1920

caagucguga aggggaagga ggccggugaa gugaggguau gccugcacgu ccagaaaagu     1980

acccgggacc gccucaggga gggccagauc caguccgugg ugacuuacga ucuggcacug     2040

gacagcgggc ggccgcauuc cagggccguc uucaaugaga ccaagaacag cacgcgccgg     2100

caaacccagg uguugggccu gacucagacc ugugaaacuc ucaaacugca gcucccaaau     2160

ugcauugagg aucccguaag ucccaucgug cugagguuga acuuuagccu ggucgguacc     2220

ccacuguccg ccuucgggaa ccuccgcccc gugcuggcag aagacgccca acgguuguuu     2280

acggcgcugu ucccauuuga gaagaauugu ggcaacgaua auauuugcca ggacgaucuc     2340

aguaucaccu ucagcuuuau gucccuggac ugucucgugg ucggcgggcc gagggaguuc     2400

aacgugacug uaaccgugcg caaugauggu gaagacagcu accggacuca ggucaccuuc     2460

uuuuuccccc uggauuuguc cuauaggaaa gugaguacgc ugcaaaacca gcgcagccag     2520

cgguccugga ggcuggccug cgagagugca agcuccaccg aagugagcgg cgcccucaag     2580

aguacuuccu guagcauuaa ucacccaauc uuucccgaga acuccgaagu caccuucaau     2640

auuacuuuug acguggauag caaggccagu cuggggaaca aauugcugcu caaggcaaau     2700

guaaccuccg agaacaauau gccacgcacg aacaaaaccg aguuccagcu ggaacugccc     2760

gugaaguacg ccgucuauau gguggugacu agccauggcg ucaguaccaa auaccucaau     2820

uuuacugcgu ccgagaacac cagccgggug augcaacacc aguaucaggu auccaaccug     2880

ggucagagga gcuugccgau cagucuggug uuccucgucc cagugcgccu gaaucaaacu     2940

gugaucuggg accggcccca ggucaccuuu agcgaaaacu uguccaguac gugccauacc     3000

aaggagaggc ugccaagcca cuccgacuuc cucgccgaac ugcgcaaggc acccguggua     3060

aauuguagca uugccgugug ccagaggauc cagugcgaua uuccguuuuu cgggauccaa     3120

gaggaauuua acgcaacucu gaaaggcaau cucuccuucg acugguacau uaagaccagu     3180

cacaaccauc uguugaucgu cagcacugcc gagauccugu ucaaugauuc cguguuuacc     3240

cuccugcccg gccagggggc guucgugcgg agccagacgg agaccaaagu cgaaccauuu     3300

gaggugccca acccauugcc ccugauugua gguaguuccg ugggcgggcu ccugcugcuc     3360

gcccugauca cugcagccuu guauaagcug ggcuucuuua aaaggcagua caaggacaug     3420

augagcgaag guggcccacc gggggccgag ccccaauga                            3459


<210>  870
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  870
auguucagcc ugaagacccu ccccuuucug uugcugcucc acgugcagau cuccaaagcc       60

uucccaguca guagcaagga gaaaaacacu aagaccgugc aagacuaccu ggaaaaauuu      120

uaucaguugc cguccaauca guaccagagu acgaggaaga acggcacuaa uguaauugug      180

gagaagcuga aagaaaugca acgguucuuu gggcucaacg ucaccgguaa gcccaaugag      240

gaaacccugg auaugaugaa aaagccacgc ugcggcgugc ccgacagcgg gggcuucaug      300

cugacuccag guaaccccaa augggagagg accaaucuca cguaucggau ccgcaacuac      360

acuccacagc uguccgaggc agaaguggag agggccauua aggaugcguu ugaauugugg      420

agcgucgccu ccccgcugau cuucacccgg auuagucagg gggaggcaga caucaauauc      480

gccuuuuauc agcgcgauca uggcgacaac agccccuucg auggcccaaa ugggauucuc      540

gcacacgccu uucaacccgg ucagggcauc gggggcgacg cgcauuucga ugccgaggaa      600

acuuggacca acaccuccgc aaauuacaac cuguuccugg uggccgccca cgaguuuggu      660

cauagcuugg ggcucgcaca caguuccgac ccaggcgccc ugauguaucc caauuacgcg      720

uucagggaaa cgagcaacua cucccugccg caggaugaca uugauggcau ccaggccauu      780

uaugggcuca guagcaaccc cauccaacca acuggucccu ccaccccaaa acccugugac      840

ccaagccuga cuuuugacgc aauuaccacc uugcggggcg agauccuguu cuuuaaggau      900

cgcuacuucu ggaggcggca cccgcagcuc cagcgcguag aaaugaauuu uaucagucug      960

uucuggcccu cccugccaac ugggauucaa gccgcauaug aggacuuuga uagggacuug     1020

aucuuccucu uuaagggcaa ccaguacugg gcccugagcg guuaugauau ucugcagggc     1080

uaccccaaag acaucaguaa uuauggguuc ccauccagcg ugcaggccau ugaugcggca     1140

gucuuuuacc ggagcaagac guacuucuuc gugaacgacc aauuuuggcg cuaugauaau     1200

cagaggcagu ucauggagcc cggcuacccg aaauccauca guggggccuu uccagguauc     1260

gaaagcaagg uggacgccgu cuuccagcaa gagcacuuuu uccauguguu uuccggcccc     1320

cgguauuacg cauucgaucu cauugcccag cgcguaacca ggguggcgcg ggggaacaaa     1380

uggcugaauu gcagguaugg cuga                                            1404


<210>  871
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  871
augagccugu ggcagccccu cgugcugguc uugcuggugc ucggcugcug uuucgccgca       60

ccaaggcaac ggcaguccac ccugguauug uuuccggggg accugcgcac uaaccucacc      120

gauaggcagc uggccgagga auaccuguau cgguacgguu auacgcgcgu ggcggagaug      180

aggggcgaaa guaagagccu cgggcccgcc cuguugcugc uccagaaaca acugucccug      240

ccagagacug gcgaauugga cagugcaacc cucaaggcca ugcggacccc caggugcggu      300

gucccagauc uggggagguu ccagacuuuu gagggcgacc ugaaauggca ccaucacaau      360

aucaccuacu ggauucagaa cuauagcgag gaucuccccc gggcagugau cgacgaugcc      420

uucgcgcgcg ccuuugcacu gugguccgcc gugacgccau ugacuuucac cagggucuac      480

agccgggacg ccgauauugu gauccaguuu ggcguagcag aacaugggga cgguuauccg      540

uucgauggca aggacgggcu gcucgcccac gcguuucccc caggccccgg uauucaaggg      600

gaugcccauu ucgacgacga ugagcugugg ucccugggca aaggcguggu cgugccaacu      660

cgcuuuggga augcagacgg ugccgcaugu cacuuccccu ucaucuuuga aggcaggagu      720

uacagcgccu gcaccaccga ugggcggucc gacggcuugc cgugguguag cacgacugcc      780

aacuacgaua ccgacgaucg cuucgguuuu ugccccagug agaggcucua uacucaggac      840

ggcaaugcgg augggaagcc augucaguuc cccuuuaucu uccagggcca auccuacagc      900

gcaugcacca ccgacgggcg guccgauggu uaucgcuggu gugccacuac ggccaacuac      960

gacagggaca agcuguuugg cuucugccca acccgggcag auaguacugu gaugggcggg     1020

aauagcgccg gugagcugug cgucuuuccc uucaccuuuc ucggcaaaga auauuccacc     1080

uguacuagcg aggggagggg cgacgggcgc cuguggugcg cgacgaccag uaacuucgau     1140

uccgacaaga aauggggcuu uuguccagau caggguuaca gcuuguuccu gguggccgca     1200

cacgaguucg ggcaugcccu cggccuggac cacaguuccg uaccggaagc acugauguau     1260

cccauguacc gguuuacuga agguccaccc uugcauaagg augacgugaa uggcauuagg     1320

caccucuacg ggccacgccc cgagccggag ccacggccac ccaccaccac uacgccccag     1380

cccaccgccc caccgacugu cugccccacc ggcccaccca cugugcaccc aagcgaaagg     1440

cccaccgccg ggccgacggg cccacccagc gcagguccaa ccgggccccc gacugccggc     1500

cccuccaccg cgacuaccgu gccacugagu cccgucgaug acgccuguaa cgugaauauc     1560

uucgaugcaa uugccgagau cggcaaccaa cuguaucucu uuaaagacgg gaaguacugg     1620

cgcuucagcg aaggucgggg cuccaggcca caggggcccu uucugauugc cgauaaaugg     1680

ccagcauugc cgcggaagcu ggacagcgua uucgaggaac gccucaguaa gaaacuguuu     1740

uucuuuuccg gccgccaggu gugggucuau acgggugcga gcgugcuggg gccccggcgc     1800

uuggacaagc ugggccucgg cgccgauguc gcacagguga ccggggcccu gagguccggu     1860

cggggcaaaa ugcuccuguu cagugggcgc agguuguggc gguuugacgu gaaggcccaa     1920

augguagauc caaggagcgc auccgaggug gaccgcaugu uccccggcgu cccacuggau     1980

acucaugacg uguuccagua ccgggagaaa gccuauuuuu gccaggauag guucuacugg     2040

cgcgucagca gucgguccga acucaaucag guggaccaag uggguuaugu aaccuacgau     2100

auccugcagu gucccgagga cuga                                            2124


<210>  872
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  872
augcaccccg gcgugcuggc cgcauuccuc uuucugagcu ggacccauug cagggccuug       60

ccacugccgu ccggggguga cgaggaugac cucagugaag aggaucugca guucgcggaa      120

cgguacuugc gcagcuauua ccaccccacu aaccuggccg gcauccucaa ggagaaugca      180

gccuccagua ugaccgaaag gcugcgggag augcagagcu uuuucgggcu ggaggucacg      240

ggcaaacucg acgauaacac ucuggacgug augaagaaac cacgcugugg uguacccgau      300

gugggggaau auaaugucuu uccaaggacc uugaaguggu ccaaaaugaa ccugaccuac      360

cggauuguga auuauacucc cgacaugacc cauagcgagg uggaaaaggc auucaagaaa      420

gccuuuaagg ucugguccga ugugacgcca cucaacuuca cucgccugca cgacggcauc      480

gcggauauua ugaucaguuu uggcauuaaa gagcaugggg acuucuaccc guuugauggu      540

cccagcggcc uguuggccca cgcauuccca cccgggccaa auuauggcgg ugacgcccac      600

uucgacgaug acgagaccug gacuuccagc aguaaggggu acaaccucuu ucugguagcc      660

gcacaugagu ucggccacuc ccugggccuc gaucauagca aagaccccgg ggcccugaug      720

uuuccgaucu acaccuauac cgguaagucc cacuucaugu ugcccgauga cgaugugcaa      780

ggcauccaga gucuguacgg gccaggcgac gaggauccca auccaaaaca ccccaagacg      840

ccagacaagu gcgauccgag ccucucccug gacgcgauua cuagccugag gggugaaacc      900

augaucuuua aagaccgguu cuuuuggcgc uugcaucccc agcaagucga ugccgaacuc      960

uuccugacua agaguuuuug gccagaacug cccaacagga uugacgcagc cuaugagcac     1020

ccaucccaug aucucaucuu cauuuuucgg ggccgcaaau ucugggcacu gaauggguac     1080

gacaucuugg agggcuaucc caagaaaauu agcgaacugg ggcucccgaa ggaggugaag     1140

aaaaucagug ccgccgugca cuuugaagau accgguaaga cccugcuguu cuccggcaac     1200

caggucugga gguacgacga uacuaaucau aucauggaca aagauuaucc acgguugauu     1260

gaggaagacu uccccgggau cggcgauaag guggacgcgg uauacgagaa aaacgguuac     1320

auuuacuuuu ucaauggccc cauccaguuu gaguauagca uuuggagcaa ccgcaucgug     1380

agggucaugc cagcaaacuc cauccucugg uguuga                               1416


<210>  873
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  873
auggagaccc ccaacacuac cgaagacuac gauacgacua ccgaguucga cuauggcgau       60

gccaccccau gccagaaggu gaaugaaagg gcauuugggg cccaacugcu cccgccccug      120

uacagcuugg ucuucgugau cggucuggua ggcaacauuc ucgugguccu gguguuggug      180

caguauaaac ggcugaagaa uaugacuucc aucuaccucc ugaaccuggc gauuagugac      240

cuccuguuuu uguucacccu gccauuuugg aucgauuaua aacucaagga cgauuggguc      300

uucggggacg ccauguguaa aauucugagc ggcuuuuacu auacgggucu guacuccgag      360

aucuucuuua ucauuuugcu cacuaucgau cgcuaccugg caauugugca cgccguauuc      420

gcacugaggg cccggaccgu gacuuuuggg gucaucacca guauuaucau uugggcgcuc      480

gccauccugg caagcaugcc cggcuuguau uucuccaaga cccaguggga auuuacgcau      540

cacacuugca gccugcauuu uccacacgag ucccuccgcg aguggaagcu guuccaggcc      600

cugaaauuga aucucuuugg ccuggugcug ccccuccugg ugaugaucau uuguuacacc      660

gggaucauua agaucuugcu gaggcggcca aacgagaaaa agaguaaagc cguccgccuc      720

auuuucguga ucaugaucau uuucuuccug uuuuggacuc cguauaaucu gaccaucuug      780

auuagcguau uccaagacuu ucucuucacc caugaaugcg aacaguccag gcaccuggau      840

cuggcagugc aggucacuga ggugaucgcc uacacgcacu guugcgugaa ccccgucauu      900

uaugcguuug ugggugagcg guuccgcaag uaccucaggc agcuguuuca ucggcgcgua      960

gccgugcacu uggucaaaug gcugccauuc cucagcgugg acaggcugga acgggucagu     1020

uccaccagcc ccuccacugg cgagcaugaa cugagugcag gguucuga                  1068


<210>  874
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  874
augaggaccc uggccugccu ccuguugcug ggcugugggu accucgcaca cgugcuggcc       60

gaggaagcgg agaucccccg ggaagucauu gagcgcuugg ccaggagcca gauccauucc      120

auucgggacc ugcaacgccu ccuggaaauc gauagugugg guagcgagga cucccuggau      180

accagucuca gggcacacgg cguacaugcc acuaagcacg ugccagagaa acggccgcug      240

cccauucgca ggaagcggag caucgaagag gcagucccag ccgugugcaa aacgcgcacu      300

gugaucuaug aaauucccag gucccagguc gacccaacca gcgcgaacuu cuugaucugg      360

cccccaugug uggagguaaa gcggugcacc ggguguugca auacuuccag ugugaaaugu      420

cagccgagcc gcguccauca cagguccgug aagguggcca aggucgagua cgugcggaaa      480

aagcccaaac ugaaggaagu acaggugcgc cucgaggaac accuggagug cgcaugugcc      540

accacgagcc ugaacccaga uuauagggaa gaggacacug gccggccccg cgagaguggu      600

aaaaagagga aacggaagag guugaagcca accuga                                636


<210>  875
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  875
augaacaggu gcugggcccu guuccucagc cuguguugcu acuugcggcu gguguccgca       60

gagggcgacc ccaucccaga ggaacucuau gaaaugcuga gugaucacag cauucgcucc      120

uuugacgauu ugcagaggcu gcuccauggg gacccgggug aggaagaugg cgccgagcug      180

gaccugaaua ugacccggag ucacagcggg ggcgagcucg aaucccuggc gcgcgguagg      240

cggagcuugg ggucccugac uaucgccgag cccgcaauga uugccgaaug uaagacccgc      300

acggaggucu ucgagaucag uaggcggcuc auugaucgca cuaacgcaaa uuuucuggug      360

uggccacccu gcguagaagu gcaaaggugu agcggcugcu guaacaaucg gaacguccag      420

ugccgcccaa cccaggugca gcugaggccc gugcaagucc ggaaaaucga gaucgugcgc      480

aagaaaccaa uuuucaagaa agccaccgua acuuuggaag accaucucgc guguaagugc      540

gagaccgugg ccgcagccag gccggucacg cggucccccg gcgggagcca ggaacagcgc      600

gccaagacuc cacagaccag ggugacuauc cggaccguga ggguccgccg gcccccaaaa      660

gguaagcaca ggaaauuuaa gcauacccac gauaaaacgg cacugaagga gacucugggc      720

gccuga                                                                 726


<210>  876
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  876
augagccugu ucggccuccu guugcugacc uccgcccucg cagggcagag gcaagguacu       60

caggccgaga guaaccugag cuccaaguuu caguucagua gcaauaaaga acagaacggc      120

gugcaagacc cccagcacga gcggaucauu accgucucca cgaaugggag cauccauucc      180

ccacgcuuuc cgcacacuua ccccaggaac accguguugg uauggcggcu gguggcgguc      240

gaagagaaug uguggauuca gcucaccuuc gaugaacgcu uuggccugga ggacccagag      300

gaugacaucu gcaaguauga uuucguggaa gucgaggaac ccagugacgg uacuauucug      360

gggagguggu guggcagcgg caccgugcca gggaaacaga ucuccaaggg uaaccaaauc      420

cggauucgcu uuguaagcga ugaguacuuc cccagugagc caggcuuuug cauccauuau      480

aauauuguga ugccgcaguu cacggaagcc gucuccccca gcgugcuccc acccuccgca      540

cugccauugg accugcucaa caaugccauc acugcauuua guacccugga ggaucugauu      600

agguacuugg aacccgagcg guggcagcuc gaccuggaag aucuguaucg cccgacuugg      660

cagcuccugg ggaaagccuu cguguucggc aggaaaagcc gggucgugga cuugaaccug      720

cucaccgagg agguacgccu guacuccugu acccccagga auuuuagcgu gaguauccgg      780

gaggaacuga agcgcacgga uacuauuuuc uggccagguu gcuugcucgu caagaggugu      840

gggggcaacu gcgcguguug ccugcacaau uguaacgaau gccaaugcgu gcccuccaag      900

gugaccaaaa aguaucauga gguccugcag cuccggccaa aaacuggcgu gcgcgggcug      960

cacaagagcu ugaccgacgu agcccuggaa caccaugagg agugugacug cguguguagg     1020

gguaguaccg gcggguga                                                   1038


<210>  877
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  877
augcacaggc ugaucuucgu guacacccuc auuugcgcca acuuuuguag cugccgggac       60

acuuccgcaa cgccccagag ugccagcauc aaggcgcugc gcaaugccaa cuugaggcgg      120

gaugaccugu aucgcaggga ugagaccauu caagucaaag gcaaugggua cgugcagucc      180

ccacgguucc cgaacaguua uccccgcaau cuccuguuga cuuggaggcu gcauagccag      240

gaaaacaccc ggauccagcu cguauuugac aaucaauucg gucuggagga agcagagaac      300

gauauuuguc gcuacgacuu uguggaaguc gaggauaucu ccgagaccag cacuaucauu      360

aggggccggu ggugcgggca caaggaagug ccaccccgca ucaaauccag gaccaaucag      420

auuaagauca cguucaaaag ugacgauuau uuuguggcca agccaggcuu caagauuuac      480

uauagccugc ucgaggacuu ucagcccgca gccgcguccg aaacuaacug ggagagcguc      540

accaguucca ucagcggugu guccuacaau aguccaagcg uaacugaucc gacccugauu      600

gccgacgcau uggauaaaaa gaucgccgag uucgacaccg uggaagaccu gcucaaauac      660

uuuaaccccg aguccuggca ggaagaucug gagaauaugu aucuggacac gccacgguac      720

cgcgggagga gcuaucauga ucggaagagu aaagucgacu uggaucgccu caacgacgau      780

gccaagaggu acuccuguac uccccggaau uauagcguga acaucaggga ggaacugaaa      840

cuggcaaacg uggucuucuu cccacgcugc cuccuggugc aacggugugg cggcaauugc      900

ggguguggua ccguaaacug gaggaguugc acuugcaauu ccggcaagac cgugaagaaa      960

uaccacgagg ucuugcaguu ugaacccggg cauauuaagc gccggggcag ggccaaaacc     1020

auggcgcugg uggacaucca gcucgaucac cacgagcgcu gugacugcau uuguagcagc     1080

cggccgccca gguga                                                      1095


<210>  878
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  878
auggugaccc acagcaaguu ccccgccgca ggcaugucca ggccacugga caccagucuc       60

cggcugaaaa cuuuuagcuc caagagugag uaccaguugg ucgugaacgc cguacgcaaa      120

cugcaagaaa gcggguucua uugguccgcg gugacgggug gcgaggccaa ucuccuguug      180

agcgcagaac cggccgggac uuuucugauc agggauucca gugaccagcg gcauuucuuu      240

acccucagcg ucaagaccca guccggcacu aaaaaccugc gcauucagug cgaggguggg      300

agcuucaguc ugcaauccga ucccaggagc acccagccag ugccccgguu ugacugugug      360

cucaagcugg uccaccauua caugccaccc ccaggcgcac cguccuuccc caguccaccc      420

acggaaccaa gcuccgaggu gcccgagcag ccgagcgccc agcccuugcc aggcaguccc      480

ccacgcaggg cguauuacau cuauuccggg ggugaaaaga uuccccuggu acucagccgg      540

ccacugaguu ccaauguggc cacucugcaa cacuugugcc gcaaaaccgu caacggccau      600

cucgauagcu acgagaaggu gacucagcug ccggggccca ucagggaauu ucuggaccag      660

uaugaugcac cacucuga                                                    678


<210>  879
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  879
auggugccca gcgccggcca gcuggcacuc uucgcccugg ggaucgucuu ggcggccugc       60

caagcacugg agaacuccac caguccacuc agcgccgacc cgcccguggc agccgcggua      120

gugucccacu uuaaugauug uccagacagu cauacucagu ucugcuuuca cgguaccugu      180

agguuccugg uccaggaaga uaagcccgcc ugcguguguc auagcggcua cgugggggca      240

cggugcgagc acgccgacuu gcuggccguc guggcagccu cccagaaaaa gcaagcgauu      300

acggcccucg uaguggucag caucguggca cuggccgugc ugauuaucac uuguguccuc      360

auucauugcu gucaggugcg caaacacugc gaauggugca gggcacugau cugucggcac      420

gagaagccau ccgccuugcu gaaaggccgc accgccugcu gucauaguga aaccguagug      480

uga                                                                    483


<210>  880
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  880
augcccccaa gcggccugag gcuccugccg uugcugcucc cccuguugug gcugcucgug       60

cugaccccag ggcggcccgc cgcaggucug uccacuugca agaccaucga cauggagcuc      120

gucaaacgca agaggauuga agccauccgg ggccagauuc ugaguaaauu gcgccuggcg      180

agcccacccu cccaagggga ggugccaccg ggcccccucc cagaagccgu acuggcacug      240

uacaacagua cgagggaucg gguggccggu gagagcgcag aacccgagcc agagcccgaa      300

gccgacuauu acgcgaagga ggucacucgc guguugaugg uggaaaccca caaugagauc      360

uaugauaaau ucaagcaguc cacccauagc auuuacaugu uuuucaacac uuccgagcuc      420

agggaagccg ucccggagcc cgugcugcug agucgggcag aacuccgccu guugaggcug      480

aagcucaaag uagagcagca cguggaacug uaucagaagu acagcaauaa cuccuggcgg      540

uaucugagca aucgcuugcu cgccccaagu gacucccccg aguggcugag cuuugauguc      600

accggggugg ugaggcaaug gcugucccgg ggcggcgaga ucgaaggguu ccgccucagu      660

gcccauugua gcugcgacuc cagggauaac acgcugcagg ucgacaucaa ugguuuuacu      720

accggccggc gcggggauuu ggcaacuauu cacggcauga acaggccauu ccugcuccug      780

auggccacgc cccuggagcg ggcgcagcau uugcagagca guaggcaccg ccgggcccuc      840

gacaccaauu acuguuuuuc cagcaccgag aaaaacugcu gugugaggca acuguacauc      900

gauuuccgca aggaccuggg uuggaaaugg auucacgaac caaaggggua ucaugcaaau      960

uuuugccucg gcccgugucc cuacaucugg agucuggaua cucaguauuc caaaguauug     1020

gcccuguaca accagcacaa uccaggcgca agcgccgccc ccugcugugu gccacaggcg     1080

cucgaacccc ugccgauugu cuauuacgug gggcggaagc caaaggugga gcaacugagc     1140

aacaugaucg ucagguccug caaaugcagu uga                                  1173


<210>  881
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  881
augcacuacu gcgugcugag cgccuuccuc auccugcauu uggucaccgu ggcacugucc       60

cucaguacuu guagcacccu ggacauggau caguuuauga ggaagcggau ugaggccauc      120

cgcggccaaa uuuuguccaa acugaagcuc acgagucccc cagaagacua uccggagccc      180

gaagagguac cacccgaagu gaucagcauu uacaacucca cuagggaucu gcugcaggag      240

aaagcgagcc ggcgcgccgc agccugcgag agggaacggu ccgacgagga auauuacgca      300

aaggaggucu auaaaaucga uaugccaccc uucuuuccaa gugagaaugc caucccgccc      360

accuucuacc gcccauauuu uaggauugug cgguucgacg ugagcgcgau ggaaaagaac      420

gccuccaauc ucgucaaggc agaguuucgc guguucaggc ugcagaaccc caaagcccgg      480

guaccagaac agcgcaucga guuguaccaa auucucaaga gcaaagaucu gaccaguccc      540

acucagaggu acaucgacuc caaggugguc aaaacccggg ccgaagggga guggcugagc      600

uuugauguga cggacgcagu gcacgagugg cugcaucaca aggaucgcaa uuuggguuuc      660

aaaauuuccc uccauugucc gugcuguacu uuugucccca guaacaauua uaucauucca      720

aacaagagcg aggaacugga agccagguuc gcgggcaucg acgggaccuc cacuuacacc      780

agcggcgauc agaagaccau caaaaguacg cggaagaaaa auuccgguaa gacuccccau      840

cugcuccuga uguugcugcc aagcuaucgc cucgagaguc agcaaaccaa caggcggaaa      900

aagagggccc uggacgcagc cuacugcuuc cgcaaugugc aggacaacug uugccugcgg      960

cccuuguaua uugauuuuaa gagggaccuc ggguggaaau ggauccacga accaaagggc     1020

uacaaugcaa acuucugugc cggcgccugc ccguaucugu gguccagcga uacucagcac     1080

agccgcguac ugucccucua caauaccauu aaccccgagg cgagugcaag cccaugcugu     1140

gugucccagg accuggagcc cuugaccauc cuguacuaua uugggaaaac uccaaagauc     1200

gaacaacuca gcaacaugau cgucaaaagu ugcaaguguu ccuga                     1245


<210>  882
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  882
augaagaugc aucugcagag ggcccucgug guccuggcau ugcugaacuu cgccaccgug       60

agccucuccc ugaguacuug caccacguug gacuuuggcc acaucaaaaa gaaacgggua      120

gaggcgauuc gcgggcaaau ccugagcaag cucaggcuga cuuccccacc cgaaccgacc      180

gugaugaccc acguccccua ccaggugcug gcccucuaua auaguacucg ggagcuguug      240

gaagagaugc auggugaacg cgaggagggc uguacccagg aaaacacgga gagcgaauac      300

uaugcaaaag agauucacaa guucgauaug auccaggggc uggccgagca uaaugaacuc      360

gcagugugcc caaagggcau uacuuccaaa gucuuuaggu ucaacgugag cuccguagag      420

aagaaucgga ccaaccuguu ucgcgccgag uucagggugc ugcggguccc caauccaagu      480

agcaaacgca acgaacaaag gaucgaauug uuucagaucc uccggcccga cgagcacauu      540

gcgaagcagc gcuacaucgg ugggaaaaau cugccaacua ggggcaccgc cgaguggcug      600

uccuucgaug ugaccgacac ggugcgggaa uggcuccugc gcagggagag caacuugggc      660

cuggaaauua guauccacug uccgugccau acuuuucagc ccaaugggga uauucucgag      720

aacauccacg aagucaugga gauuaaguuc aaaggugugg acaaugagga ugaccauggc      780

cgcggggauc ugggccggcu gaagaagcaa aaagaccacc acaacccaca uuugauccuc      840

augaugauuc ccccacacag gcuggauaau cccggucaag ggggccagcg gaagaaaagg      900

gcacuggaca ccaacuauug uuuucgcaac cucgaagaga auugcugugu acggccgcug      960

uacaucgauu ucaggcagga cuugggcugg aagugggugc augaacccaa aggguauuac     1020

gccaacuucu gcuccggucc augucccuac cugcgcagcg ccgacacuac ccacuccacc     1080

guccucggcc uguauaauac ucugaaccca gaggcaagug ccagccccug cugcgugcca     1140

caggauuugg aaccgcucac gauccuguac uauguggggc ggacccccaa ggucgagcag     1200

cuguccaaua uggugguaaa gagcuguaaa ugcaguuga                            1239


<210>  883
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  883
auggcccccg uggcagucug ggccgcgcug gccgugggcc ucgagcugug ggcagccgca       60

cacgccuugc cagcgcaggu agccuucacc ccguacgcac ccgaaccagg gagcacuugc      120

aggcugcggg aguauuacga ccaaaccgcc cagauguguu gcuccaagug uagucccggu      180

cagcaugcca aaguguuuug cacgaagacu agcgauaccg ucugugacuc cugcgaagau      240

aguaccuaua cucagcucug gaacugggug ccagaguguc ugagcugcgg cucccgcugu      300

agcuccgacc aaguggaaac ccaggcaugc acgagggagc agaaucggau cugcacuugu      360

cgccccgggu gguacugcgc cuugaguaaa caggagggcu guaggcugug cgcgccacuc      420

cggaaguguc gcccggguuu cggggucgcc aggcccggca ccgaaacuag cgauguggua      480

ugcaaaccau gugcacccgg caccuuuucc aacaccacga gcaguacuga cauuugccgg      540

ccacaccaaa ucuguaaugu ggucgccauu cccgggaacg cauccaugga ugccgugugc      600

accagcacuu ccccgacccg caguauggcc cccggugcgg ugcaucugcc acagcccguc      660

agcaccaggu cccagcacac ucagccaacg cccgagccaa gcaccgcacc gaguacuucc      720

uuccugcucc ccaugggccc aaguccccca gccgaaggga gcaccggcga cuuugcccug      780

cccguggguu ugaucguagg ggugaccgca cugggccucc ugauuaucgg cgucgugaau      840

ugcgugauca ugacucaagu caagaagaaa ccgcuguguu ugcagcggga ggccaaggug      900

ccacaucucc ccgcggauaa agcccgcggg acgcaggguc ccgagcaaca gcaucugcug      960

auuaccgcac cauccagcag cuccaguagc cucgaaucca gcgccagugc acuggacagg     1020

cgggccccca cucgcaacca gccacaggcc ccgggcguag aggcauccgg ggccggcgaa     1080

gcgagggcca gcaccgguuc cagugauagc ucccccggcg ggcacggcac ccaagugaau     1140

gucacuugca ucgugaacgu cuguagcagu uccgaccaca gcucccagug caguagccag     1200

gcauccagca cgauggggga uaccgacagu uccccaagcg agucccccaa ggacgaacag     1260

gugccauuca gcaaagagga gugugccuuu cggagucaau uggaaacucc cgagacccug     1320

cucgguagca cugaagagaa gccgcugcca cugggcgugc ccgaugccgg gaugaaacca     1380

uccuga                                                                1386


<210>  884
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  884
augcccguga ugaggcuguu cccaugcuuu cuccagcugu uggccggccu ggcacucccg       60

gccgugcccc cacaacagug ggcgcugagc gccgggaacg guuccaguga ggucgaagua      120

gugcccuucc aggaggucug gggccggagc uacugucgcg cauuggaaag gcugguggac      180

guggucuccg aguauccaag ugaaguggag cacauguuua gccccuccug cguaagccuc      240

cugcggugua ccgggugcug uggcgaugag aaucugcauu gcgugccagu cgaaacugcc      300

aacgugacca ugcagcuccu gaagauccgc uccggugaca ggccgaguua cguggaguug      360

acguucagcc aacacguccg gugugaaugc cgcccccuga gggagaaaau gaagccagag      420

cggcgcaggc ccaaagggcg gggcaagcgc aggcgggaaa aacagcgccc aacugauugu      480

caucucugcg gcgacgcagu gcccaggcgg uga                                   513


<210>  885
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  885
augaccgaca ggcagacuga uaccgccccc agcccauccu accaucugcu cccgggccgg       60

cgcaggacgg uggacgcagc cgcgagucgg gggcaagguc ccgagccagc ccccggcggg      120

ggcgucgaag gugugggggc acgcggcgua gcccugaagu uguucgugca gcugcucggc      180

ugcagcaggu uugggggugc agucgugcgg gccggcgagg cggaaccauc cggggccgca      240

cgcagugcca gcuccggcag ggaggaaccc cagccagagg agggugaaga ggaagaggag      300

aaagaagagg aacgggggcc gcaguggcgc cugggcgcca ggaagcccgg cagcuggacu      360

ggggaggcag ccgugugugc ggauuccgcc ccagcagccc gggcacccca agccuuggcc      420

cgcgcgagug guaggggcgg gcgggucgca cgcaggggcg ccgaagagag cgguccaccc      480

cacuccccga gccggcgcgg cagugccucc agggcagggc ccggccgggc cagcgagacc      540

augaacuucc ugcucuccug ggugcacugg agucuggcgc ugcuccugua uuugcaucac      600

gccaaaugga gccaggcagc cccaauggca gaagggggug gccagaauca ucacgaggua      660

gugaaguuua uggacgucua ccagaggucc uauugccacc ccaucgaaac ccugguggau      720

auuuuccaag aguacccaga cgaaaucgag uauauuuuua aacccagcug ugugccacuc      780

augcgcugcg ggggcuguug caacgaugag ggucuggaau gugucccgac ugaggaaagu      840

aauaucacca ugcagauuau gcggaucaag ccccaucagg gccagcacau cggggagaug      900

uccuuccugc aacauaacaa gugcgaaugu aggcccaaaa aggaccgcgc ccggcaggag      960

aaaaagagcg ugaggggcaa agggaagggc cagaaacgca agcggaagaa aaguagguac     1020

aaguccugga gcguauaugu gggugcccgg ugcugcuuga ugccauggag ccucccaggg     1080

ccccacccgu guggcccaug cuccgagcgc aggaaacacc uguuugucca agauccccag     1140

acguguaagu gcaguuguaa aaauacugac agccggugca aggcacgcca gcuggaacuc     1200

aacgagagga ccugucggug cgauaagccc aggcgcuga                            1239


<210>  886
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  886
augaacuucc ugcucagcug ggugcacugg ucccuggccu ugcugcucua ccugcaucac       60

gcaaagugga gucaggccgc gcccauggcc gagggcgggg gucaaaauca ucacgaaguc      120

gugaaauuua uggacguaua ucagaggagc uacugccauc caaucgagac cuugguggau      180

auuuuccagg aauauccgga cgagaucgaa uacauuuuua agcccuccug ugucccacug      240

augcggugcg gcggguguug caacgaugag ggccucgagu gugugcccac ugaagagagu      300

aauaucacca ugcagauuau gcgcaucaaa ccacaccaag gucagcacau cggggaaaug      360

agcuuccugc agcauaacaa gugcgagugu aggcccaaaa aggaccgggc acgccaggag      420

aagaaauccg ugaggggcaa gggcaaaggg caaaagcgga aacgcaagaa aagcagguau      480

aaguccugga gugucuacgu gggugcccgg ugcugucuga ugccauggag ccucccgggc      540

ccccacccau gcgggcccug cuccgaacgc aggaagcauc uguuuguaca ggauccacag      600

acguguaaau gcagcuguaa gaauacugac agucggugca aagcacgcca guuggagcug      660

aacgaaagga ccugucggug cgauaagccc aggcgcuga                             699


<210>  887
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  887
augagccccc ugcucaggcg gcuguugcug gccgcacucc ugcaguuggc cccagcgcaa       60

gccccggugu cccagcccga cgcaccaggc caccagcgca aggucgugag uuggaucgau      120

guauacacca gggccacuug ccagccccgg gagguggucg ugccacugac cguggaacuc      180

auggggacgg ucgcaaaaca acuggugccc agcuguguaa cugugcagcg cugcgguggc      240

uguugcccag acgaugggcu ggaguguguc ccgaccggcc agcaucaggu gaggaugcaa      300

auucucauga uccgguaucc cuccagucag cugggugaaa ugagcuugga ggaacacucc      360

cagugcgagu gucgcccaaa gaaaaaggac agcgccguga aacccgauag ggcggccacc      420

ccacaucacc ggccccagcc gcgcuccguc cccggguggg acagugcacc aggcgccccc      480

agcccagccg auauuacuca ucccacccca gcaccgggcc ccuccgccca cgcggcccca      540

agcacgacca gugcacugac ucccgggcca gccgcagccg ccgcggacgc agccgccucc      600

agcguggcaa aggguggcgc cuga                                             624


<210>  888
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  888
augcaucugc ucggcuucuu uagcguggcc ugcucccugu uggcagccgc gcugcucccc       60

gggccaaggg aggccccggc agccgcagcc gcguucgaaa guggucugga cuugagcgau      120

gccgagcccg acgcaggcga agccaccgcc uacgcaucca aggaucugga ggaacagcuc      180

cggaguguca gcuccgugga cgagcugaug acuguacugu auccagagua cuggaaaaug      240

uauaaguguc aacuccgcaa agggggcugg cagcacaaca gggaacaggc caaucugaac      300

agccggaccg aggaaacgau caaguuugcg gccgcacacu acaauacuga gauuuugaaa      360

uccaucgaua acgaguggcg caagacccag ugcaugccca gggaagugug uauugacguc      420

gguaaggagu ucgggguggc caccaauacu uucuucaaac cacccugcgu gagugucuau      480

cgguguggcg gcugcuguaa cagcgaaggg cugcaaugca ugaauaccuc cacgagcuac      540

cucaguaaga cucuguuuga gaucaccgug ccacuguccc aggguccgaa acccguaacu      600

auuagcuucg caaaccauac cuccugucgc ugcaugagua aguuggaugu guauaggcag      660

guccacagca ucauccggcg cucccuccca gccacccugc cccagugcca agccgcgaau      720

aaaacguguc caacuaacua cauguggaau aaccauauuu guaggugccu ggcacaggaa      780

gacuuuaugu ucagcaguga ugccggcgac gauuccaccg acggguuuca cgauaucugc      840

ggccccaaua aggagcucga cgaggaaacu ugucagugcg ugugucgggc cggucugcgc      900

ccggcaagcu gcgggcccca caaagaguug gacaggaaca guugucagug cgugugcaag      960

aauaagcugu ucccauccca auguggcgcc aaccgggaau uugaugagaa uaccugccag     1020

ugugucugca aacgcaccug ucccaggaac cagccacuca accccggcaa gugcgcgugu     1080

gaaugcacug agagcccaca aaaaugucug cugaagggga aaaaguuuca ucaccagacg     1140

ugcagcuguu accggcgccc gugcaccaau aggcagaagg ccugcgagcc cgguuucucc     1200

uauagugaag aggugugucg gugcguacca agcuacugga aaaggcccca gauguccuga     1260


<210>  889
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  889
auguacaggg aguggguggu cgugaacgua uucaugaugc uguaugugca gcucguccaa       60

ggcagcucca augaacacgg gcccgugaag cggaguagcc aguccacccu ggagcgcagu      120

gaacagcaga ucagggccgc aagcuccuug gaggaacugc uccggauuac ucauagcgag      180

gacuggaaac uguggcgcug cagguugcgg cugaaguccu uuaccaguau ggauagccgc      240

uccgccagcc acaggaguac gcgguucgcg gccacuuuuu acgacaucga gacccucaaa      300

gugauugaug aagaguggca acgcacccag uguuccccaa gggaaacuug cgucgaggug      360

gcaagcgagc uggguaaguc caccaacacg uucuuuaaac cgcccugugu aaauguguuc      420

cggugcggcg gguguugcaa cgaagagagu cugaucugua ugaauacuag caccuccuau      480

auuagcaagc agcucuuuga aaucaguguc ccacugacuu ccgugcccga guuggugcca      540

gucaaggugg ccaaccauac cggcugcaaa ugucugccca ccgcaccacg ccacccguac      600

agcaucauua ggcggaguau ccagauuccc gaagaggacc gcugcuccca uagcaagaaa      660

cucugcccaa ucgauaugcu gugggacagc aauaagugua aaugcguacu gcaagaggaa      720

aaccccuugg ccgguacgga ggaucacucc caccuccagg aaccagcgcu gugugggccc      780

cauaugaugu ucgacgagga uaggugcgaa ugugugugca agacuccgug ucccaaagac      840

cugauucagc acccaaagaa uugcaguugu uuugagugca aggagagccu cgaaaccugc      900

ugucagaaac auaagcuguu ccaccccgau acuugcuccu gugaggaccg gugcccauuu      960

cacacccgcc ccugugccag cggcaaaacc gcaugcgcca agcauuguag guucccaaaa     1020

gaaaagcggg ccgcacaagg cccgcacagu aggaagaacc ccuga                     1065


<210>  890
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  890
auggcgguca uggccccgag aacgcuagug cuauugcucu cgggcgcgcu cgcgcucacg       60

caaacguggg cg                                                           72


<210>  891
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  891
auggacgcga ugaagcgcgg gcucugcugc guacuacugc ucugcggcgc gguauucguc       60

ucaccauca                                                               69


<210>  892
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  892
augggcgugc acgagugccc ggccuggcuc uggcucuugc ucucgcucuu gagcuugccc       60

uugggcuugc ccgugcucgg g                                                 81


<210>  893
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  893
augaaauggg ucaccuucau cucccuccuc uuccucuucu ccucugccua cucc             54


<210>  894
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from 
       Artificial____cleavage site-Furin

<400>  894
aggaggagga ggaagagg                                                     18


<210>  895
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  895
auggacuccg acgaaaccgg cuucgaacac uccggccucu gggucuccgu ccucgccggc       60

cuacuacuag gcgccugcca agcccacccc auccccgacu cauccccacu ucuacaauuc      120

ggcggacaag ucagacaacg auaccucuac accgacgacg cccaacaaac agaagcccau      180

cucgaaauaa gagaagacgg caccgucggc ggcgccgccg accaaucccc cgaaucccua      240

cuccaacuca aagcacucaa acccggcguc auccaaaucc ucggcgucaa aaccucccgc      300

uuccuaugcc aacgccccga cggcgccuua uacggcuccc uacacuucga ccccgaagcc      360

ugcucuuuuc gcgaacuccu acucgaagac ggcuacaacg uauaccaauc cgaagcccac      420

ggccuacccc uacaccuccc cggcaacaaa ucaccccacc gcgacccagc cccacguggc      480

cccgcacgcu uccucccacu accaggccuc ccacccgccc uccccgaacc acccggcauc      540

cucgcacccc aaccacccga cguaggcucc ucagaccccc ucuccauggu cggccccucc      600

caaggccgcu cacccucaua cgccucauaa                                       630


<210>  896
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  896
augcacuccu ucccaccccu ccuccuacuu cucuucuggg gcguaguauc ccacuccuuc       60

cccgccacac uagaaaccca agaacaagac guagaccugg uccaaaaaua ccuagaaaaa      120

uacuacaacc ucaagaacga uggacgacaa gucgaaaaac gccgcaacuc cggcccgguc      180

guagaaaagc uaaaacaaau gcaagaguuc uucggccuaa aagucacugg caaaccagac      240

gccgaaaccc ucaaagucau gaaacaacca cgaugcggcg ucccagacgu cgcacaauuc      300

guccucacag aaggcaaccc ccgaugggaa caaacccacc ucaccuaccg aauugaaaac      360

uacacaccug accugcccag agccgacgua gaccacgcca uagaaaaagc cuuucaacuc      420

uggucaaacg ucacaccccu caccuuuacc aaagucucgg aaggccaagc cgacauaaug      480

auuagcuucg uucgaggcga ccacagagac aacucccccu ucgacggacc cggcggcaac      540

cucgcccacg ccuuccaacc cggcccgggu auaggcggag augcacauuu cgacgaagac      600

gaacgcugga caaacaacuu cagagaauac aaccuccacc guguagcagc ccacgaacua      660

ggccacucac ucggacucuc acacagcacc gacaucggag cccuaaugua cccauccuac      720

acuuucuccg gagacguuca acucgcccaa gacgacaucg acggcaucca agcaaucuac      780

ggccgcuccc aaaacccagu acaacccauc ggaccacaga cucccaaagc cugcgacucc      840

aaacucaccu uugacgcaau caccaccauc cgaggcgaag ucauguucuu caaagaccgc      900

uucuacaugc gcacgaaccc cuucuaccca gaagucgaac ucaacuucau aucagucuuc      960

uggccccaac uaccaaacgg ccuugaagca gcauacgaau uugccgacag agacgaaguc     1020

cgcuucuuca aaggaaacaa auacugggcc guccaaggcc aaaacguccu ucacggcuac     1080

cccaaggaca uauacuccuc cuucggcuuc ccccgaacag ucaaacacau cgacgcggca     1140

cuguccgaag aaaauaccgg caagacauac uucuucgucg ccaacaaaua cuggcgguac     1200

gacgaauaca aacgauccau ggaccccggc uaccccaaaa ugauagcaca cgacuucccg     1260

ggaaucggcc acaaagucga ugcaguauuc augaaagacg gauucuucua cuucuuccac     1320

ggcacacgcc aauacaaauu cgaccccaaa acaaaacgca uccucacccu ccagaaagcc     1380

aacagcuggu ucaauugccg caaaaacuaa                                      1410


<210>  897
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  897
augcacuccu ucccuccccu acuacuccua cuauucuggg gagucguauc acacuccuuc       60

guccucaccg aaggcaaccc ucgaugggaa caaacccacc ucacuuaccg aaucgagaac      120

uacacccccg accucccacg agccgacguc gaccacgcca ucgaaaaagc cuuucaacua      180

ugguccaacg ucacaccccu caccuucacu aaaguaagcg aaggccaagc cgacaucaug      240

aucagcuucg uccgcggaga ccaccgagac aauucccccu ucgacggccc aggaggcaac      300

cuagcccacg ccuuucaacc aggacccggc auaggaggcg acgcccacuu cgacgaagac      360

gaacgaugga caaacaacuu ccgcgaauac aaccuccaca gaguagccgc ccacgaauua      420

ggccacuccc uaggacucuc acacucaacc gacauaggug cccucaugua ccccuccuac      480

accuucagcg gcgacgucca acuagcccaa gacgacaucg acggcauaca ggccaucuac      540

ggccgaucuc aaaauccagu ccaacccaua ggaccacaga caccaaaagc cugugacucc      600

aaacucaccu ucgacgccau caccaccaua cgcggagaag ucauguucuu uaaagacaga      660

uucuacaugc guaccaaccc cuucuaccca gaaguagaac uaaacuucau aucugucuuc      720

uggccacaac uccccaacgg ccuagaagca gcauacgaau uugcugacag agacgaagua      780

cgauucuuca aaggcaacaa auacugggcc guccaaggcc aaaacguacu acacggcuac      840

ccaaaagaca ucuacuccuc cuucggcuuc ccccgcacag ucaaacacau cgaugccgca      900

cucagcgaag aaaacaccgg aaaaaccuac uucuucgucg ccaacaaaua cuggcgauac      960

gaugaauaca aacgauccau ggaccccgga uaccccaaaa ugaucgccca cgacuucccc     1020

ggaauaggcc acaaagucga cgcaguuuuc augaaagacg gcuucuucua cuucuuccac     1080

ggaaccagac aauacaaauu cgaccccaaa accaaacgca uccucacccu ccaaaaagcc     1140

aacuccuggu ucaacugccg caaaaacuaa                                      1170


<210>  898
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  898
augaagaaaa acauccucaa aauacucaug gacucguauu cuaaggaauc caaaauccaa       60

accgucagac gcgucacuag cgucucccuc cucgcggugu accuaacuau gaauacgucc      120

agccuagucc ucgcaaagcc uaucgagaac accaacgaca ccagcauuaa aaacguugag      180

aagcuacgca acgcgccaaa cgaggaaaac ucaaagaaag ucgaagacag caaaaaugac      240

aaaguagagc acguuaaaaa cauagaagaa gccaaggugg aacaaguagc accggaaguc      300

aaaagcaaaa guacccuacg cagcgccagc auugccaaca ccaacagcga aaaguacgac      360

uucgaguauc uuaacgggcu cagcuacaca gaacuaacaa accugaucaa aaacauaaaa      420

uggaaccaaa uaaacgguuu guucaacuac agcacagggu cacaaaaauu cuucggcgau      480

aaaaaccgcg uccaggccau cauaaacgcc cuacaagaaa gcggccgcac auacaccgcg      540

aacgacauga agggaauaga aaccuucacg gagguauuaa gggcgggguu cuaccuaggc      600

uacuacaaug acggacucuc auaccuaaac gaccgcaacu uccaagacaa gugcaucccc      660

gccaugauag ccauacagaa aaacccaaau uuuaaacucg gcacggccgu ccaagacgaa      720

guuauaacau ccuuagggaa acucaucgga aacgccucgg ccaacgccga aguggugaac      780

aacugcgucc ccguacuuaa gcaauuccgc gaaaaccuaa accaauacgc acccgacuac      840

guuaagggga ccgcggucaa cgaauugaua aaaggaaucg aguucgacuu uagcggagca      900

gcauaugaaa aggacgugaa gacaaugccc ugguacggca agauugaucc guucauuaac      960

gaacucaagg cccucggacu auacggaaac auaaccucag caaccgagug ggcuucagau     1020

guaggcaucu acuaccugag caaguucggc cuauacagca ccaaccgcaa cgacauugug     1080

caaaguuuag aaaaagcagu cgacauguac aaguacggca agauugcauu uguagcgaug     1140

gaacgaauaa cgugggacua cgacggcauc ggcuccaacg gaaagaaagu cgaccacgac     1200

aaguuccugg augacgccga gaagcacuac cuccccaaga cauacaccuu cgacaacggc     1260

accuucauca uccgagccgg cgacaaagua ucggaagaaa agaucaagag acuauacugg     1320

gccuccagag aagucaaauc ccaauuccac cgagucgucg gaaacgacaa ggcccuagaa     1380

guaggaaacg ccgacgacgu auuaacuaug aaaauuuuua acagcccaga agaauacaaa     1440

uucaacacca auauuaacgg cguaucaaca gacaacggag gacuguacau agaaccccga     1500

gggacauucu acacauacga acggacccca caacaaucca ucuuuagccu ggaagaacuc     1560

uucagacacg aauacaccca cuaccuacag gccagauacc uagucgacgg uuuaugggga     1620

caaggccccu ucuacgagaa aaaccgacuc acaugguuug acgagggcac agccgaguuc     1680

uucgcaggau caacaagaac cagcggcgug cucccgcgaa agucgauccu uggcuauuua     1740

gcgaaagaca aaguagacca cagauacagc cuaaagaaaa cacugaacuc aggcuacgac     1800

gauagcgacu ggauguucua caacuauggc uucgcaguag cgcacuaccu uuacgaaaaa     1860

gacaugccga cguucaucaa gaugaacaaa gcaauacuaa acaccgacgu uaaaucguac     1920

gacgaaauaa ucaaaaagcu guccgacgau gccaacaaaa acacagaaua ccaaaaccau     1980

auccaggaac ucgcggacaa guaccagggg gcaggaaucc cccuagucuc ggacgacuac     2040

cuaaaagacc acggcuacaa gaaagcaagc gaaguauaca gugagaucag caaagccgcc     2100

ucccuaacga acacaucagu gacugcugag aaaagccagu acuucaacac cuucacacuc     2160

cgaggaacuu acacgggaga aacaucaaaa ggcgaguuca aagacuggga cgaaaugagc     2220

aagaaauuag acggcacccu agaaucacua gcgaaaaacu cuuggagcgg auacaagacc     2280

cuuaccgcau acuucacgaa cuacaggguc accagugaca acaaagugca guacgacguc     2340

guguuccacg gaguucuaac agacaacgcc gacaucucca auaacaaagc accaaucgcc     2400

aaggugacgg ggccaagcac aggagccguc ggacgaaaca uagaguucuc aggcaaagac     2460

agcaaggacg aagacgggaa gauaguaagu uacgacuggg acuucgguga cggagcaaca     2520

ucccgcggua agaacagugu gcacgcauau aagaaggccg gaacauacaa cguaacccua     2580

aagguaacgg acgacaaagg agcgacagcg accgaaucgu uuacuaucga aauaaagaac     2640

gaagacacga ccacuccaau aacaaaagaa auggaaccaa acgaugacau caaagaagcc     2700

aacggcccua uagucgaagg uguaaccgua aaaggcgacc ucaacggcuc cgacgacgca     2760

gacacguucu acuucgacgu gaaagaagac ggggacguaa caaucgaacu ccccuacucc     2820

ggcuccucaa acuucaccug gcuaguauac aaggaagggg acgaucaaaa ccacaucgca     2880

agcggaaucg auaaaaacaa uaguaaagua gggaccuuca aaucgacaaa gggaaggcac     2940

uacgucuuca uuuacaagca cgacagcgcc agcaacauaa guuacuccuu aaacaucaaa     3000

ggacuaggca acgaaaaacu uaaggaaaaa gagaacaacg acucaagcga caaagcgacu     3060

guaaucccaa acuucaauac gacaaugcaa gguucccucc ucggagacga cucacgggac     3120

uacuacagcu ucgaagucaa ggaagaaggc gaagugaaca ucgaacugga caaaaaggac     3180

gaguucggcg uaaccuggac ccugcacccc gaaagcaaca ucaacgacag gaucaccuac     3240

ggccaaguag acggcaacaa agucagcaac aaagucaaac uccgccccgg caaguacuac     3300

cuacuggucu acaaguacag cggcucagga aacuacgaac uccgcgucaa caaguaa        3357


<210>  899
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  899
augaaauggg ucaccuucau aagccuccuc uuucuguuca gcagcgcaua cucaauagcc       60

aacaccaacu cagaaaaaua cgacuucgaa uaccuaaacg gccuaagcua caccgaacua      120

accaaccuca ucaaaaacau aaaauggaac caaauaaacg gccuauucaa cuacagcacc      180

ggcagucaaa aguucuucgg ugacaagaac cgcguccagg cgauaaucaa cgcccuacaa      240

gaauccggcc gcaccuacac agccaacgac augaaaggca uagaaacauu cacggaagua      300

cuacgugcug gauucuaucu aggcuauuau aacgacggac ugagcuaccu aaacgacagg      360

aacuuucaag acaaaugcau ccccgccaug auagcaaucc agaaaaaucc caacuuuaaa      420

cucggaacgg cgguccaaga cgaggugauc acgucacuug gaaaacucau aggaaacgcg      480

agcgccaacg ccgagguagu aaauaacugc guaccagucc ugaagcaauu ccgugaaaau      540

cuuaaccaau acgccccaga cuacguaaaa ggaacugcgg ucaacgagcu cauaaaagga      600

auagaguucg acuucagcgg agccgcauau gaaaaagacg uaaagaccau gcccugguac      660

ggcaaaauag acccguucau caacgaacuc aaggcacuag gccuauacgg caacaucaca      720

agcgccaccg aaugggccuc agacgucggg aucuacuacc uaucaaaauu cggacucuac      780

agcacaaacc gaaacgacau cguacaaucc cuagaaaaag cagucgacau guacaaauac      840

ggaaagaucg cauucgucgc cauggagcgc aucacguggg auuacgacgg aauaggcuca      900

aacggaaaga aagucgacca cgacaaauuc cucgacgacg cagaaaaaca cuaccugccg      960

aaaacuuaua cguuugacaa cggcaccuuc auuauccgcg cgggcgacaa aguaucugag     1020

gaaaagauca aacgacuaua cugggcuagc cgagaaguaa aaagccaguu ccaccgagua     1080

gucggaaacg auaaggcgcu cgaaguagga aacgccgacg acguccuuac uaugaagauc     1140

uucaacagcc ccgaagaaua caaauucaac acuaacauca acggcguauc cacagacaac     1200

ggaggccuau acaucgaacc uaggggcacc uucuacaccu acgaacgcac cccacaacaa     1260

ucaaucuucu cucuugaaga acucuuccgg cacgaguaca cccacuaccu acaagcacga     1320

uaccucgucg acggccuaug gggccaagga ccauucuacg agaaaaacag acucaccugg     1380

uuugacgaag ggaccgcuga guucuucgcc ggcagcacaa gaacaucagg aguccucccc     1440

cgaaagagca uccuaggaua ccuggccaag gacaagguag aucaccgcua cagccuaaag     1500

aagacacuaa acagcggcua cgacgacucc gacuggaugu ucuauaauua cggcuucgcg     1560

guagcacacu accuguauga aaaagacaug ccaaccuuca ucaaaaugaa caaagcaaua     1620

cuaaacaccg augucaaaag cuacgaugaa auuaucaaaa agcugagcga cgacgcaaau     1680

aaaaacaccg aauaucaaaa ccacauccag gaacucgccg acaaauacca aggcgcaggg     1740

aucccccugg ugucagacga cuaccuaaaa gaccacggcu acaagaaagc cucggaaguc     1800

uacuccgaaa ucaguaaagc agccagccua accaauacau caguuacagc cgaaaagagc     1860

caguacuuca acacauucac acugaggggc accuacacag gcgaaacuuc caaaggggag     1920

uucaaggacu gggacgaaau gagcaagaag cucgacggca cccucgaauc acucgcuaaa     1980

aauucauggu cgggauacaa gacuuuaacg gcauacuuca cgaacuaccg agugacaagc     2040

gacaacaaag uccaauacga cgucgucuuu cacggcgucc ugaccgacaa cgcagacaua     2100

uccaacaaca aagcaccgau cgcaaaaguc accggaccga gcaccggggc agucgggaga     2160

aacaucgagu ucucaggcaa agacuccaag gacgaggacg gcaaaaucgu cagcuacgac     2220

ugggacuucg gagacggcgc aacaagccgg ggcaagaacu caguccacgc cuacaagaaa     2280

gcaggaaccu acaacguaac acuaaaagua accgacgaca aaggggcaac agccaccgaa     2340

ucguucacca uagaaaucaa aaacgaagac accaccaccc ccauuacgaa agagauggaa     2400

ccgaaugacg acaucaaaga ggcuaacggc ccuaucgucg agggcguaac cguaaaaggc     2460

gaccuuaacg gaucggauga cgcagacacc uucuacuucg acguaaaaga agauggcgac     2520

gucacuaucg agcucccaua cuccggcucc agcaacuuca ccuggcucgu auacaaggaa     2580

ggugacgacc agaaccacau cgcuucgggg auagacaaaa auaacucuaa aguuggcaca     2640

uucaagagca caaaaggccg gcauuacguu uucauauaca agcacgacuc cgcuucaaac     2700

aucaguuaca gccucaacau caagggacug ggaaaugaga agcucaaaga gaaagagaac     2760

aacgacuccu ccgacaaagc cacgguaaua cccaacuuca auacgaccau gcaagguucu     2820

cuacucggcg acgacagcag ggacuacuac ucguuugagg ucaaggagga aggcgaagua     2880

aacauagagc uugacaagaa agacgaguuc ggugugacgu ggacacuaca cccagagucc     2940

aacauaaaug acagaauaac auacggccag guagacggca acaaggugag caacaaaguc     3000

aaacuccgac ccgguaaaua cuaccuauua gucuacaaau acuccggaag cgggaacuac     3060

gagcuacgcg ucaauaagug a                                               3081


<210>  900
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  900
augaaauggg uaaccuucau aucccuccug uuccuauucu caucagcaua cagcaugaag       60

aaaaacaucc ucaaaauccu aauggauagc uacucaaagg aaaguaaaau ccagacgguu      120

cgccgaguga cguccgucuc ccuucuagca guauaccuca cuaugaacac aagcucccua      180

guccuggcca aacccauuga aaacaccaac gacaccucua uaaagaacgu agaaaaacuc      240

cgaaacgccc caaacgagga aaacucaaag aaaguagagg auucuaaaaa cgacaaagua      300

gaacacguca aaaacauaga agaggccaaa guagaacaag ucgccccgga agucaaaucc      360

aaaagcacgc ugcggucggc gucucgccgg cgacggaaac gcauagcaaa cacaaacucg      420

gaaaaauacg acuucgaaua ccucaacgga cucagcuaca ccgaacugac gaaccucauc      480

aaaaacauca aauggaacca aaucaacgga cuguucaacu acuccacagg aucccaaaag      540

uucuucggcg acaaaaaccg aguacaggcg aucauaaaug cccugcagga aagcggcaga      600

acuuauaccg caaaugacau gaagggcauc gaaacguuca ccgagguccu gagagcgggc      660

uucuaccuag gauacuacaa cgacggacuc agcuaccuca acgaccgcaa cuuucaggau      720

aaaugcauac cggcaaugau cgcaauccag aaaaacccca acuucaaacu uggaacagcg      780

guacaagaug aggucaucac aucgcuggga aagcuaauag gaaacgccuc cgcaaacgcc      840

gaaguaguca acaacugcgu cccuguauua aaacaauucc gugagaaccu caaccaauac      900

gcccccgacu acgucaaagg caccgccguc aacgaacuga uaaagggcau agaguucgac      960

uucaguggag cagcauacga aaaagacguc aagaccaugc ccugguacgg caaaaucgau     1020

cccuucauca augaacucaa agcgcuuggc cucuacggaa acauaaccuc ugccacagaa     1080

ugggcaagcg acgucggaau auauuaccua uccaaauucg gccucuacag cacaaacaga     1140

aacgacauag uacagucacu cgaaaaagcu gucgacaugu acaaauacgg aaagauagca     1200

uucgucgcaa uggaacgcau aacaugggac uacgacggca uaggguccaa cggcaagaaa     1260

guagaccaug acaaguuccu agacgacgca gaaaaacacu accugcccaa gaccuacacc     1320

uucgacaacg gaaccuucau aauccgagca ggcgacaaag uaagcgaaga gaaaauaaaa     1380

cgccuauacu gggccagucg agaagucaaa ucacaauucc accgagucgu aggcaacgac     1440

aaggcacuag aagugggaaa cgccgacgau guccuaacua ugaaaaucuu caacagcccg     1500

gaagaauaca aauucaacac caacaucaac ggggucucaa ccgacaacgg cgggcuguac     1560

auagagccgc gcggcacguu cuacacguac gagcgcacac cccaacaaag caucuuuucg     1620

cuagaagaac uuuuccgaca cgaauauacc cacuacuuac aggcucgaua ccucguagau     1680

ggccuauggg gccaaggccc auucuacgaa aagaacagac ucaccugguu cgacgaagga     1740

accgcagagu ucuucgcagg aucgaccagg acgagcggcg uccucccaag gaaauccaua     1800

cuuggauacc ucgcaaaaga uaagguagac caccgguacu cacuuaaaaa gacucucaac     1860

ucaggauacg acgacuccga cuggauguuc uacaacuacg gcuuugccgu ggcucacuau     1920

cuguacgaaa aggacaugcc caccuucauc aagaugaaca aagccauccu caacaccgac     1980

guaaaaagcu acgacgaaau aaucaagaaa cucucagacg acgcgaauaa aaacacagaa     2040

uaccaaaauc acauacaaga gcucgccgac aaauaccagg gcgcggggau accgcucguc     2100

ucugacgacu accucaaaga ccacggguac aagaaagcca gcgaggucua cagugaaauc     2160

agcaaagccg ccucgcuaac caacaccagc guaacggcgg agaaaagcca guacuucaac     2220

accuucacac uaagaggaac cuauaccggu gagaccagca aaggcgaguu caaggacugg     2280

gacgaaaugu ccaagaaauu agacgggacc cuagaaucgc uggccaaaaa cuccuggagu     2340

ggguauaaga cccuuaccgc guacuucaca aacuacagag ugaccagcga caauaaaguc     2400

caguacgaug ucguguucca cggcgugcua acagacaaug cagacaucuc aaacaacaaa     2460

gccccaaucg ccaaagucac gggacccagc acaggcgccg uaggccgcaa caucgaauuu     2520

ucagguaagg auucaaaaga cgaagacggc aagaucguca gcuacgacug ggacuucgga     2580

gacggcgcca ccagcagagg gaaaaacuca guacacgcgu acaagaaggc cgggaccuac     2640

aacgucaccc uaaaaguuac ggaugacaaa ggcgccacag ccacggaauc cuucaccaua     2700

gaaaucaaga acgaggacac aacuaccccc auaaccaaag agauggagcc aaacgaugac     2760

auaaaagaag cuaacggccc aaucguggaa ggcguuacug ucaaagggga ccuaaacggc     2820

ucagacgacg ccgacaccuu cuacuuugac guaaaagaag acggggacgu cacaauagaa     2880

cucccauacu ccggaaguag caacuucacc uggcuagugu acaaggaagg ggaugaucaa     2940

aaccacauag cauccggcau agacaagaac aacucaaaag uugggaccuu caaaucgacc     3000

aaaggccggc acuacguauu caucuacaaa cacgacuccg caaguaauau aucauacagc     3060

cuaaacauaa aggggcuggg aaaugaaaaa cuuaaggaaa aagaaaacaa cgacaguagc     3120

gacaaagcaa cagugauccc caacuucaau acaaccaugc aaggcucacu ccucggagau     3180

gacucaaggg acuacuacuc auucgaagug aaggaagaag gcgaagucaa caucgaacuc     3240

gacaagaagg acgaguucgg cgucaccugg acccuccacc cugaaucaaa cauaaacgac     3300

aggaucaccu acggccaagu agacggaaac aaagugucaa acaagguaaa acucagaccg     3360

gggaaauauu accuacuggu guacaaauau ucuggaagcg gaaacuacga acuacgaguc     3420

aacaaauag                                                             3429


<210>  901
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  901
augaacuucc ucaaaauaau ccuaaaccga ggcaaaacca ugaagcgcaa augccucagc       60

aagagacuca ugcucgcaau caccauggcu acaaucuuca caguuaacuc aacucucccc      120

aucuacgccg cgguagacaa aaacaacgca accgccgccg uccaaaauga aucuaaacga      180

uacacaguca gcuaccuaaa aacccuuaac uacuacgacc ucguagaccu gcucgugaaa      240

accgaaaucg agaaccuccc ggaccuguuc caauauucca gcgaugccaa agaguucuac      300

gggaacaaaa cacgaauguc guucaucaug gacgaaaucg gacgccgagc gccccaauac      360

accgagauug aucauaaggg aaucccgacg cucgucgaag ucguccgagc cggguucuau      420

cucggcuucc acaacaagga acucaacgag auaaacaaac gcucuuucaa ggaacgcguc      480

auaccgucca uacuugccau acagaaaaac cccaauuuca agcucggaac agaaguacaa      540

gacaaaaucg uauccgccac cggccugcua gccggaaacg aaaccgcacc accagaaguc      600

gucaacaacu ucacucccau ccuucaagac ugcaucaaga acaucgacag auaugcauug      660

gacgaccuaa aaucaaaagc acuguucaac guucuagccg cgcccacaua ugauauaacc      720

gaauaccuca gagcaacaaa ggagaaaccc gaaaacacuc ccugguacgg caaaaucgac      780

ggcuucauca acgaacuaaa gaaacucgca uuauacggca aaaucaacga caacaacagu      840

uggaucauag acaacggcau auaccacauc gcgccacuag gaaaacuaca cucuaacaac      900

aaaaucggaa ucgaaacacu aaccgaaguc augaagguau accccuaccu gagcaugcaa      960

caccuucaau cugcagauca aaucaaacga cacuacgaca gcaaagacgc cgagggaaac     1020

aagaucccau uagacaaauu caagaaagaa ggaaaagaga aauacugccc aaagaccuac     1080

acguuugaug auggcaaagu aaucauaaag gccggcgcac gcgucgagga agaaaaaguc     1140

aaacgccugu acugggcguc aaaagaaguc aacucccaau ucuuccgagu cuauggcauc     1200

gacaaacccc ucgaggaagg caaccccgac gacauacuga caauggucau uuacaacucg     1260

ccugaggaau acaaacugaa cucagugcua uacggcuacg acaccaacaa cggcggcaug     1320

uacaucgaac ccgaaggcac uuucuucacu uacgagagag aggcccaaga auccacguac     1380

acacuagaag aacuuuuccg acacgaguac acccacuacc uccaaggccg uuacgcaguc     1440

ccgggacaau ggggacgaac gaaacucuac gacaacgaca ggcugaccug guacgaagag     1500

ggcggggcgg aacuauucgc agggagcacc aggacaucgg ggauacuucc caggaaaucc     1560

aucgucucca acauccacaa cacaacacga aauaaucggu auaaacugag cgauaccguc     1620

cacucaaaau acggcgcguc auucgaguuc uacaacuacg ccuguauguu cauggacuac     1680

auguacaaca aagauauggg aauccucaac aaauuaaacg accucgcuaa gaacaacgac     1740

guagacggcu acgacaacua cauaagagac cuauccucaa acuacgcucu gaacgacaaa     1800

uaccaagacc acaugcagga acgaaucgac aacuacgaaa accucaccgu cccguucguc     1860

gccgacgacu accucgugag acacgccuac aaaaacccca acgaaaucua cagcgagauc     1920

agcgaagucg ccaaacucaa ggacgcaaaa uccgagguca aaaagucuca auacuucagc     1980

accuucacuc uacgcggcuc auacacgggc ggcgccucca aaggcaaauu agaagaccaa     2040

aaagccauga acaaguuuau cgacgacagc cucaagaaac uugacaccua cucguggagu     2100

ggcuacaaaa cucuaaccgc cuacuuuaca aacuacaaag ucgacucguc caaccgcgug     2160

acauacgacg uagucuucca cggguaccua ccgaacgagg gagacagcaa aaacagccuc     2220

cccuacggaa aaauaaacgg cacauacaag ggaaccgaaa aagagaaaau aaaauucucc     2280

uccgaaggcu cguucgaccc cgaugguaag auaguauccu acgaauggga cuucggagac     2340

ggcaauaaaa gcaaugagga aaacccagaa cacucauacg acaaaguagg gaccuacacc     2400

guuaaauuaa aagucacgga cgacaaagga gagucgagcg ucucaaccac caccgccgag     2460

auaaaagacc uauccgaaaa caaacuaccc guaaucuaua ugcacguccc aaaaucaggc     2520

gcacucaauc aaaagguugu cuucuaugga aaaggcaccu acgacccgga cggcagcaua     2580

gcgggcuacc aaugggacuu uggcgacggu ucggacuucu cgucagagca aaacccuagc     2640

cauguauaca ccaagaaagg agaauacacc guaacccugc gagugaugga uucaucuggc     2700

caaaugucug agaaaacaau gaaaauaaaa aucaccgacc caguauaccc caucgguacc     2760

gaaaaagaac cuaacaacag uaaagaaacu gcaagcggac ccaucguccc cggcauuccu     2820

gucucaggaa ccaucgaaaa caccagcgau caggacuacu ucuacuuuga uguaaucacc     2880

cccggcgaag ucaaaaucga caucaacaaa cuaggauacg gcggagccac augggugguc     2940

uacgacgaga acaauaacgc cgucucuuac gcaaccgacg auggacaaaa ccucagcggu     3000

aaauuuaaag cagacaagcc cggacgcuac uacauccacc uauacauguu uaacggcucc     3060

uacaugcccu aucgaauuaa cauugagggc ucaguaggcc gcuga                     3105


<210>  902
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  902
augaaaagaa aaugccuauc caaacgccuc augcuugcaa uaacaauggc cacaauauuu       60

accgucaacu ccacccuacc aaucuacgcc gccguagaua aaaacaacgc aacagcagcc      120

guccaaaacg agagcaaacg auacaccgua ucauaccuca agacccuaaa cuauuacgau      180

cuaguggacc uccucguaaa gacggagauc gaaaacuuac cggaucuauu ucaauacucc      240

uccgacgcaa aagaguucua cgguaacaag acacgaaugu ccuucaucau ggacgaaauc      300

ggacggcgcg caccccaaua caccgaaauc gaccacaaag gcauacccac ccuugucgaa      360

guuguacgag ccggcuucua cuuaggauuc cacaacaagg aacucaacga aaucaacaaa      420

cgcuccuuca aagaacgagu cauccccucc auccucgcua uucagaagaa cccaaacuuc      480

aagcucggga ccgagguaca agauaagaua gucagcgcca ccggccugcu ggccggcaau      540

gagaccgcgc ccccagaggu aguaaacaau uucaccccaa uccuacaaga uugcaucaag      600

aauaucgacc gcuacgcccu ggacgaccua aaauccaagg cccucuucaa cgugcuggcc      660

gcgcccaccu acgauaucac cgaauaccuc agagcuacca aagagaaacc cgagaacacu      720

cccugguaug gcaagauaga cggcuuuaua aacgaacuca aaaagcuagc acuguacggc      780

aagaucaaug auaacaauuc auggaucauc gacaacggga uauaccacau ugccccguua      840

gguaaacugc acagcaacaa uaaaauagga aucgagaccc uaacugaggu caugaaagua      900

uaucccuauc uuagcaugca acaccuacaa uccgcggacc aaaucaagcg ccacuacgac      960

agcaaagacg cugaggggaa caaaaucccc cuggacaagu ucaagaaaga gggcaaggag     1020

aaauacugcc caaaaaccua caccuucgac gacggcaaag ucauaaucaa agccggcgcg     1080

agaguagagg aagaaaaagu aaagcggcuc uacugggcca gcaaagaagu caacagucaa     1140

uucuuccgcg ucuacggcau cgauaaacca cuagaagagg gaaaucccga cgacauacua     1200

acaaugguaa uauacaacag cccagaggag uacaaacuga acuccguccu uuacggauac     1260

gauacaaaca acgggggaau guauauagaa ccggaaggca cauuuuucac cuacgaacgc     1320

gaggcccagg aaucaacaua uacacucgag gaguuauucc gccacgaaua cacccacuac     1380

cuacagggac gcuacgcagu accagggcag uggggccgca caaagcucua cgauaacgac     1440

cgccuaacgu gguacgaaga agggggcgcc gaacucuucg ccggauccac ccgcaccagc     1500

gggauccuac cgcgaaagag uauagugagc aacauccaua acaccacgcg caacaaccgc     1560

uacaagcucu cagacacagu ccacagcaag uacggagcau cguucgaguu cuacaacuac     1620

gcauguaugu ucauggacua cauguacaac aaagacaugg gcauccucaa caaacucaac     1680

gaucucgcga aaaauaacga cgucgacgga uacgacaacu auauccgcga ccucucaucc     1740

aacuacgcac ucaacgacaa auaccaagac cacaugcagg aacgaauaga caacuacgaa     1800

aauuuaaccg uaccauucgu agccgacgac uaccuaguac gacacgccua caaaaacccu     1860

aacgaaaucu acuccgagau cuccgaaguu gccaaacuca aagaugccaa aucagaaguc     1920

aagaaauccc aguacuucag cacauucacu cugagaggca gcuacacggg cggcgcgucc     1980

aaaggaaaac uagaagauca gaaagccaug aacaaauuca ucgacgacuc ucuaaagaaa     2040

cucgacacau acucguggag cgguuacaaa acacugacug ccuacuuuac caacuacaaa     2100

gucgacaguu caaaucgagu caccuacgac gugguauuuc acgguuaccu acccaacgaa     2160

ggggacucca aaaacucacu accuuacgga aaaauaaaug ggaccuacaa aggcacagaa     2220

aaagagaaaa ucaaauucuc cuccgaaggc agcuucgacc cugacggaaa gaucgugagc     2280

uaugaauggg acuucggcga cggcaacaaa ucaaacgaag aaaaccccga gcauucauau     2340

gacaagguag gaaccuacac agucaagcug aaaguaaccg acgacaaagg ggaaucaagc     2400

guaagcacua ccaccgccga gaucaaggac uuaagcgaaa acaaacugcc aguaauuuau     2460

augcacgucc caaaaucagg cgcccuaaac cagaaggugg uauuuuacgg uaaagggacg     2520

uacgaucccg acggcagcau cgccggcuau cagugggacu ucggugacgg cagcgacuuc     2580

ucaagcgaac aaaaccccag ccacguuuac acgaaaaagg gcgaauacac agugacacuu     2640

agagucaugg auagcucggg ucaaaugagu gagaaaacga ugaaaauaaa gaucaccgac     2700

cccguguacc ccaucggcac cgaaaaggaa ccgaacaacu caaaagaaac cgccuccggg     2760

cccaucguac ccgggauccc uguaucuggc acaauagaaa acacaagcga ccaagacuac     2820

uucuacuucg acgucauaac ccccggcgaa gucaaaaucg auaucaacaa acucggauac     2880

ggcggagcga cauggguagu guacgacgaa aacaacaacg caguauccua cgccacagac     2940

gacggccaaa accucuccgg caaauucaag gccgacaagc ccggacgaua cuacauacac     3000

cucuacaugu ucaacggauc auacaugccc uaccggauaa acaucgaagg aucgguggga     3060

cgguaa                                                                3066


<210>  903
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  903
augaaauggg ucacauuuau cagccuccuu uuccuuuuca gcucggccua cagcguccaa       60

aacgaaagua aaagauauac cguauccuau cucaaaacuu uaaacuauua cgaccuagua      120

gaccuccugg uaaagacuga aauagaaaac cugccagacc uauuccaaua cagcuccgac      180

gcuaaggagu ucuacgggaa caaaacccgc auguccuuca ucauggacga aaucgggcga      240

cgcgcaccac aguacaccga aauagaccac aaagggauuc ccacucuagu cgagguggua      300

cgagccggau uuuaccuugg auuccacaac aaagaacuca acgaaauaaa uaagcgauca      360

uucaaagagc ggguuauccc aagcauacug gcaauccaaa agaauccaaa cuucaaacuu      420

ggcacagaag uccaggacaa aauagucucc gccaccgggc uccucgccgg gaaugaaacc      480

gcacccccag aagucgugaa uaacuucacc cccauucucc aggacuguau aaagaacauc      540

gaccgcuacg cacucgacga ccuuaaguca aaagcgcucu uuaacguccu cgcggcgccu      600

acauacgaca ucacagaaua ccuucgcgcg accaaggaaa agccagaaaa caccccaugg      660

uacggaaaaa uagacggguu caucaacgaa cuaaagaaac uagcgcuaua cggcaaaauc      720

aacgacaaca acagcuggau cauugacaac ggcauauauc acauagcacc ccugggaaaa      780

cuccacagca auaacaagau cggcaucgaa acccuaaccg aaguaaugaa agucuacccg      840

uaccucucca ugcagcaucu ccagagcgcc gaccagauaa aacgacacua cgacucaaaa      900

gacgcagaag guaauaagau cccacuggac aaguucaaaa aggagggcaa agaaaaauac      960

ugcccuaaaa cauacaccuu cgacgacgga aagguaauaa uuaaagccgg agcacgagua     1020

gaagaagaaa aaguaaaacg ccucuacugg gccucaaagg aaguuaauuc acaguucuuc     1080

cgaguguacg guauagacaa accacuggag gagggaaacc cagaugacau acugacgaug     1140

guaauauaca acuccccgga agaauacaaa cuaaauucag uacuguacgg auacgacacc     1200

aacaaugggg gaauguacau cgaaccagaa ggcaccuucu ucaccuacga gcgcgaagcc     1260

caggagucga cauauacccu agaagaacug uuucgccacg aguacacgca cuacuuacaa     1320

gggcgcuacg ccguccccgg gcaguggggc cgaaccaaac uguacgacaa cgaccgccuc     1380

accugguacg aagaaggggg agcagaacuc uucgcaggau cgacccgcac cagcggaaua     1440

cucccccgca agaguauagu cagcaacauc cacaacacca ccaggaacaa cagauacaaa     1500

cuuucagaca ccguucacag caaguacggg gccuccuucg aguuuuacaa cuacgcaugc     1560

auguucaugg auuauaugua caacaaagac augggaauac uaaacaaacu caaugaccuc     1620

gccaaaaaca acgacgucga cggcuacgac aacuacaucc gagaccucag cagcaacuac     1680

gcccuaaacg acaaauauca agaccacaug caggagagga uagauaacua cgaaaaucuc     1740

accgugccau ucguagccga cgacuaccuc guacgucacg ccuacaaaaa ccccaacgaa     1800

aucuacagcg agaucucgga aguagcaaaa cuaaaagaug cuaaaucaga ggugaagaaa     1860

ucccaauacu ucucgaccuu cacucuccgc ggcuccuaca caggaggagc cagcaaaggu     1920

aaacuagagg accaaaaagc aaugaacaaa uucaucgacg acucccucaa gaaacucgau     1980

accuacagcu ggagcggaua caaaacguua accgcauauu ucaccaauua caaaguggac     2040

aguuccaacc gaguaaccua cgauguagug uuccauggcu accuacccaa cgagggcgac     2100

agcaaaaacu cacuccccua cggaaagauc aacgggacau acaagggcac ggaaaaagag     2160

aaaaucaaau ucagcucaga aggcuccuuc gaccccgacg gcaagauugu cuccuacgag     2220

ugggacuucg gggacggcaa caaaucgaac gaggagaacc cagaacacag cuacgacaag     2280

gucggcacgu acaccgucaa gcucaaagua acagacgaca agggggaauc cagcguaagc     2340

acgacaacag cagaaaucaa ggaccuaucc gaaaauaaac uaccggugau auacaugcau     2400

gucccuaaau ccggcgcucu gaaucagaag gugguauucu acgggaaggg cacguacgac     2460

cccgacggau ccauagcagg cuaccaaugg gacuucggcg augguucgga cuuuucgucc     2520

gagcagaacc caagccacgu auacacaaag aaaggggagu auaccgucac acuucgaguc     2580

auggacagca guggccagau gagugagaaa acaaugaaaa ucaaaaucac agaucccguu     2640

uacccgaucg gcacagaaaa agaaccaaac aauuccaaag agacggcguc aggcccaauc     2700

gugcccggaa uccccguuuc gggaaccaua gagaacacaa gcgaccaaga cuacuucuac     2760

uucgacguca ucaccccagg cgagguaaaa auagacauaa acaaacuagg auacggaggc     2820

gcaacauggg ugguauacga cgaaaacaac aacgcgguca gcuaugcaac ggacgacggc     2880

caaaaccuau caggaaaguu caaggccgac aagcccggaa gguacuauau acauuuguac     2940

auguucaacg gcagcuacau gcccuacaga aucaacaucg aaggcagcgu cggccgcuga     3000


<210>  904
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  904
augaaauggg ugaccuucau aucacuccuu uuccuauucu caucagcaua cucgaugaaa       60

cgcaaaugcc ucagcaaacg acucaugcua gcuaucacca uggccacaau auucaccgua      120

aacuccaccc uacccaucua cgcggcagug gacaaaaaca acgccaccgc cgcacgucgc      180

cgccggaaac gcguccaaaa cgaaaguaag cgcuauacgg ugagcuaccu caaaacucuc      240

aacuacuaug aucuaguaga ccuccuaguc aaaacggaaa uugaaaaccu ccccgaccua      300

uuccaguacu caucagacgc gaaagaguuc uacggcaaca aaacccggau guccuucaua      360

auggacgaaa ucggaaggcg agcaccccag uauaccgaga ucgaccacaa gggcaucccc      420

acgcucguag aaguaguuag agcaggcuuc uaccucgggu uccacaacaa agaacuaaau      480

gagaucaaca aacgcuccuu caaagaacgc gucauccccu caauacuagc aauccagaaa      540

aaccccaauu ucaaacuagg caccgaggua caagauaaaa ucguguccgc aacaggccuc      600

cuggcaggua augaaaccgc gccgccagaa guagucaaca acuucacacc cauccuucag      660

gacugcauca aaaacauaga cagauacgca cucgacgacc ucaaaagcaa agcacuauuc      720

aacguccucg cagcacccac auaugacaua acggaauacc uuagagcaac caaagaaaaa      780

cccgaaaaca cacccuggua ugggaaaaua gacggcuuca ucaacgagcu uaaaaagcug      840

gcacuuuacg ggaaaauaaa cgacaacaac agcuggauca uagacaacgg cauuuaccac      900

aucgcacccc uggggaaauu gcacagcaac aacaaaaucg gcauagaaac ccucacggag      960

gucaugaaag uuuacccaua ccugucaaug caacaccucc aauccgccga ccagaucaaa     1020

cgacacuacg acagcaaaga cgccgaaggc aacaagauac cacuagacaa guucaagaaa     1080

gaaggcaaag aaaaauauug cccuaaaacc uacacauucg acgacggaaa aguaaucauu     1140

aaagccggcg cccguguaga agaagaaaag gucaaacgcc uauacugggc cagcaaagaa     1200

guaaauagcc aauucuuccg cguauacggg auagacaaac cgcuagaaga aggaaacccc     1260

gacgacauac ugaccauggu aauauauaac ucaccggaag aauacaaacu caacagcgua     1320

cuauacggcu augacaccaa uaacggagga auguacaucg agccagaagg aacauucuuc     1380

acguacgaac gugaagcaca agaauccaca uacacccucg aggaacucuu ccgucacgag     1440

uacacccacu accuacaggg gcgauacgcc guacccggcc aauggggccg caccaaacug     1500

uaugacaacg accggcucac cugguacgaa gaagggggcg ccgaacucuu cgccgguucg     1560

accaggacuu caggaauacu gccccgcaag agcaucguaa gcaacaucca caauacaacc     1620

cgcaacaacc gcuacaaacu aucagacaca guccacucca aauacggagc gucauuugag     1680

uucuacaacu acgcuugcau guuuauggau uauauguaca acaaagauau ggggauccug     1740

aauaaacuaa acgaccuagc gaaaaacaac gacguugacg gcuacgacaa cuacauacgu     1800

gaccucucau caaacuacgc ccuaaacgac aaauaccagg accacaugca agaacgcauc     1860

gacaauuacg aaaaccuaac agugccuuuu gucgccgacg acuaccucgu acggcacgcu     1920

uacaaaaacc ccaacgaaau cuauucagaa aucucagaag ucgccaaauu aaaagacgcu     1980

aaauccgaag ucaagaaguc ccaauacuuc uccacauuua cccucagagg cucauacacc     2040

ggaggcgcau ccaaaggcaa acuggaggac caaaaagcca ugaacaaauu caucgaugac     2100

agucuaaaga aacucgacac cuacuccugg uccggauaca aaacgcuaac agccuacuuc     2160

acaaacuaca aaguagacag cuccaaccga gucaccuacg acgucgucuu ccaugguuac     2220

cuccccaacg aaggugacag caaaaauuca cuccccuacg gcaaaauaaa cggcaccuac     2280

aaaggcaccg aaaaggagaa aaucaaauuc ucaucggaag gcagcuucga cccagacggg     2340

aagauaguau cguaugaaug ggacuucggg gacggcaaca aauccaauga agagaacccc     2400

gaacauuccu augacaaagu ggggaccuac acaguuaagc uaaaaguaac cgacgacaaa     2460

ggcgaaucau ccguaucaac cacaacggcc gagauaaaag aucuaagcga aaacaaacuc     2520

cccguaauau acaugcacgu cccuaaaucg ggagcucuca accaaaaagu cguauucuac     2580

ggaaaaggaa cauacgaccc ugacggcucc auagccggcu accaauggga cuuuggcgac     2640

ggcagcgacu ucuccaguga gcaaaacccc ucacacgucu acacgaaaaa gggcgaauac     2700

accgugacac uucgcguaau ggacagcagc ggccagaugu ccgagaaaac caugaaaauc     2760

aagauuaccg acccagucua ccccauaggc accgaaaagg aaccgaacaa uagcaaggaa     2820

acagccagcg gcccaauagu cccggggauc cccgucuccg gcacgaucga aaacacuucc     2880

gaccaggacu acuucuacuu cgacguaaua acccccggcg aaguaaaaau cgacaucaac     2940

aaacuaggau acggaggcgc caccuggguc gucuacgaug aaaacaacaa cgccguaucc     3000

uaugccacag acgauggcca gaacuuguca ggcaaguuca aagcugacaa gcccggacgc     3060

uacuacaucc accuguacau guucaauggc uccuacaugc cauaccgaau aaacaucgaa     3120

ggaucggucg gacgcuga                                                   3138


<210>  905
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  905
augggcaccu ggauccuauu cgcaugccuc cucggagccg ccuucgccau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucucuuacg aaguccucac cccccuaaaa      120

ugguaccaau caauucgccc ccccuaucca uccuacggcu acgaacccau gggcggcugg      180

cuacaccacc aaauaauacc cguccucucc caacaacacc cccccaccca cacccuccaa      240

ccccaccacc acauccccgu cguccccgca caacaacccg ucauccccca acaaccaaug      300

augccagucc caggccaaca cucuaugacc cccauccaac accaccaacc caaccucccc      360

ccccccgcac aacaaccaua ccaaccccaa cccguccaac cacaacccca ccaacccaug      420

caaccccaac cccccgucca ccccaugcaa ccccucccac cccaaccacc ccuccccccc      480

auguucccca ugcaaccccu cccccccaug cuacccgacc uaacccucga agccuggccc      540

uccacagaca aaacaaaacg agaagaaguc gacuaa                                576


<210>  906
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  906
augccccucc caccccaccc cggccacccc ggauacauaa acuucuccua cgaaguccua       60

acaccccuaa aaugguacca auccauacgc ccacccuacc ccuccuacgg cuacgaaccc      120

augggcggau gguaa                                                       135


<210>  907
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  907
augccccucc caccccaccc cggccacccc ggcuacauaa acuucuccua cgaaguccuc       60

acaccacuca aaugguacca auccauccgc ccaccaccca ugcuccccga ccucacccuc      120

gaagccuggc ccuccaccga caaaacaaaa cgcgaagaag ucgacuaa                   168


<210>  908
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  908
auggccguca uggcaccccg aacccuaguc cuacuccuau ccggcgcccu agcccucacc       60

caaaccuggg ccaugccacu accaccccac ccaggccacc ccggcuacau caacuucucc      120

uacgaaguac ucacaccacu aaaaugguac caauccaucc gaccacccua ccccuccuac      180

ggcuacgaac ccaugggcgg cugguaa                                          207


<210>  909
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  909
auggccguaa uggcaccccg aacacucgua cuccuccucu ccggagcacu agcccucacc       60

caaaccuggg ccaugccccu ccccccacac cccggccacc ccggcuacau aaauuucucc      120

uacgaagucc ucaccccccu caaaugguac caauccaucc gccccccccc caugcucccc      180

gaccuaacac ucgaagccug gcccucaacc gacaaaacaa aacgcgaaga agucgacuaa      240


<210>  910
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  910
augggcaccu ggauccuauu cgcaugccua gucggcgccg ccuucgccau gccccuccca       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg aaguacucac cccacucaaa      120

ugguaccaau ccaugauacg cccacccuac uccuccuacg gauacgaacc caugggcggc      180

uggcuccacc accaaauaau ccccgucguu ucccaacaac acccccucac ccacacccuc      240

caaucacacc accacauccc cguagucccc gcccaacaac cccgaguccg ccagcaagcc      300

cucaugcccg uaccaggcca acaaucaaug acccccaccc aacaccacca acccaaccuc      360

ccccuccccg cccaacaacc cuuccaaccc caacccgucc aaccccaacc acaccaacca      420

augcaacccc aaccacccgu ccaacccaug caaccccuuc ucccccaacc uccccuacca      480

cccauguucc cccuccgucc ucucccaccc auccuccccg accuccaccu cgaagccugg      540

cccgccaccg acaaaaccaa acaagaagaa guagacuga                             579


<210>  911
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  911
augccccuac caccccaccc cggccacccc ggcuacauaa acuucuccua cgaaguccuc       60

accccacuca aaugguacca aucaaugaua cgaccacccu acuccucaua cggcuacgaa      120

cccaugggcg gcugguaa                                                    138


<210>  912
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  912
augccccucc ccccacaccc cggccacccc ggcuacauaa acuucuccua cgaaguccua       60

acaccacuca aaugguacca auccaugauc cgcccccccc ccauacuccc cgaccuccac      120

cucgaagccu ggcccgccac agacaaaacc aaacaagaag aagucgacua a               171


<210>  913
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  913
auggccguca uggccccacg cacacucguc cuccuacucu caggagcccu cgcacucaca       60

caaaccuggg ccaugccacu cccaccacac cccggccacc ccggcuacau caacuucuca      120

uacgaagucc ucaccccacu caaaugguac caaucaauga uacgcccacc cuacuccucc      180

uacggcuacg aacccauggg cggaugguaa                                       210


<210>  914
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  914
auggcaguca uggcaccccg cacccucguc cuacuacucu ccggcgcccu cgcccucacc       60

caaacauggg ccaugccacu cccaccccac cccggacacc ccggcuacau caacuucuca      120

uacgaagucc ucaccccacu caaaugguac caauccauga uccgaccccc acccauccua      180

cccgaccucc accucgaagc cuggcccgcc accgacaaaa ccaaacaaga agaagucgac      240

uaa                                                                    243


<210>  915
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  915
augggcaccu ggauccucuu cgcaugccuc cucggcgccg ccuucuccau gccucuacca       60

ccccaccccg gccaccccgg cuacauuaac uucuccuacg aaguccuaac uccccuaaaa      120

ugguaccaaa acaugauccg acaccccuac accuccuacg gauacgaacc caugggcgga      180

uggcuccacc accaaaucau ccccgucguc ucccaacaaa caccccaauc ccacgcccua      240

caaccccacc accacauccc caugguaccc gcccaacaac ccgguauacc ccaacaaccc      300

augaugcccc uccccggcca acacucaaug acccccaccc aacaccacca acccaaccua      360

ccccuacccg cacaacaacc cuuccaaccc caaccagucc aaccccaacc ccaccaacca      420

cuccaacccc aaucccccau gcaccccauc caaccccucc ucccacaacc accccuccca      480

cccauguucu ccaugcaauc acuccucccc gaccuccccc ucgaagccug gcccgcaacc      540

gacaaaacca aacgcgaaga agucgacuaa                                       570


<210>  916
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  916
augccccuac caccccaccc aggccacccc ggcuacauca acuucuccua cgaaguccuc       60

acaccacuca aaugguacca aaacaugauc agacacccau acaccucaua cggcuacgaa      120

cccaugggcg gcugguaa                                                    138


<210>  917
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  917
augccacuac ccccacaccc cggccacccc ggcuacauaa acuucucaua cgaaguacuc       60

accccacuca aaugguacca aaacaugauc cgacaccccu cccuccuccc cgaccucccc      120

cucgaagccu ggcccgccac cgacaaaacc aaacgcgaag aagucgacua a               171


<210>  918
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  918
auggcaguca uggcaccccg cacacucguc cuccuacuau caggagcccu cgcacucaca       60

caaacauggg ccaugccccu accaccccac cccggacacc ccggcuacau aaacuucucc      120

uacgaagucc uaacaccccu aaaaugguac caaaacauga uccgacaccc cuacaccucc      180

uacggcuacg aacccauggg cggcugguaa                                       210


<210>  919
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  919
auggccguca uggccccacg cacccuaguc cuccuccuau ccggcgcacu cgcacucaca       60

caaaccuggg ccaugccccu cccaccacac cccggccacc ccggcuacau caacuucucc      120

uacgaagucc ucacaccccu caaaugguac caaaacauga uccgccaccc aucacuccuc      180

ccagaccucc cacucgaagc cuggcccgcc accgacaaaa ccaaacgcga agaaguagac      240

uaa                                                                    243


<210>  920
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  920
augggcaccu ggauacucuu cgcaugccuc cucggcgccg ccuucuccau gccccuccca       60

ccccaccccg gccaccccgg cuacaucaac uucuccuaca uccgccaccc auacaccucc      120

uacggcuacg aacccauggg cggcuggcua caccaccaaa ucauccccgu cgucucccaa      180

caaacacccc aaucccacgc ccuacaaccc caccaccaca ucccaauggu ccccgcccaa      240

caaccaggca ucccacaaca acccaugaug ccccuacccg gccaacacuc aaugacccca      300

acucaacacc accaacccaa ccuaccccua cccgcccaac aacccuucca accccaaccc      360

guccaacccc aaccccacca accccuccaa ccccaauccc ccaugcaccc cauccaaccc      420

cuccuacccc aaccaccccu cccacccaug uucucaaugc aaucccuacu ccccgaccua      480

ccccucgaag cauggcccgc uacagacaaa acaaaacgcg aagaagucga cuaa            534


<210>  921
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  921
augggaaccu ggaucuucuu cgccugccuc cucggcgccu cccucgcaau gccccuccca       60

ccccaccccg gccaccccgg cuacaucaac uucuccuaug aaguacucac accccucaaa      120

ugguaucaaa acaugauccg ccaccccuac acauccuacg gcuacgaacc caugggcggc      180

uggcuacacc accaaaucau acccgucguc ucacaacaaa caccccaauc acacgcccuc      240

caaccccacc accacauccc cauggucccc gcccaacaac ccggcauccc ccaacaaccc      300

augaugcccc uaccaggaca acacuccaug accccaaccc aacaucacca accuaaucuc      360

ccccuccccg cccaacaacc cuuccaaccc caacccgucc aaccccaacc ccaccaaccc      420

cuccaacccc aaucccccau gcacccuauc caaccccucc ucccccaacc accccuccca      480

cccauguucu ccaugcaauc acuccuaccc gaccuccccc ucgaagccug gccugccacc      540

gacaaaacaa aacgcgaaga agucgacuaa                                       570


<210>  922
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  922
augggcaccu ggauacucuu cgccugccuc cucggcgccg cauucucaau gccccuccca       60

ccacacccag gccaccccgg auacaucaac uucuccuacg aaguacucac cccacucaaa      120

ugguaccaaa acaugauccg acaccccuca cuccuccccg accucccccu agaagccugg      180

ccagccaccg acaaaaccaa acgcgaagaa gucgacuaa                             219


<210>  923
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  923
augggcaccu ggauccucuu cgccugccuc cuaggcgcug ccuucuccau gccacuccca       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg aagaccuaua ccucgaagcc      120

auacgcaucg accgcaccgc auuuguccua accccacuca aaugguacca aaacaugauc      180

cgacacccau acaccuccua cggcuaugaa cccaugggag gcuggcuaca ccaccaaauc      240

aucccagucg ucucacaaca aaccccucaa ucucacgccc uccaaccaca ccaccacauc      300

cccauggucc ccgcccaaca acccggcauc ccccaacaac ccaugaugcc ccuccccggc      360

caacacucca ugacccccac ccaacaccac caacccaacc ucccccuccc cgcacaacaa      420

cccuuccaac cccaaccagu ccaaccccaa ccacaccaac cccuucaacc ccaauccccc      480

augcacccca uccaaccccu ccuaccacaa ccacccuuac cucccauguu uucuaugcaa      540

ucccuccucc ccgaccuccc ccucgaagcc uggcccgcca ccgacaaaac aaaacgcgaa      600

gaaguagacu aa                                                          612


<210>  924
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  924
augggaaccu ggauccuauu cgccugccuc cuaggagccg ccuucucaau gccccuacca       60

ccccaccccg gccaccccgg cuacaucaac uuuuccuacg aaguccucac cccacucaaa      120

ugguaccaaa acaugauacg ccaccccaca ccccaauccc acgcccuaca accccaccac      180

cacaucccca ugguccccgc ccaacaaccc ggcauccccc aacaacccau gaugccccuc      240

cccggccaac acuccaugac ccccacccaa caccaccaac ccaaccuccc ccuccccgcc      300

caacaacccu uucaacccca acccguccaa ccccaaccac accaaccacu ccaaccccaa      360

ucccccaugc acccaaucca accccuccuc ccccaaccac cccucccacc cauguucuca      420

augcaaucac uacuccccga ccucccccuc gaagccuggc ccgccaccga caaaaccaaa      480

agagaagaag ucgacuaa                                                    498


<210>  925
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  925
augccucucc caccccaccc cggccacccc ggcuacauca acuucuccua cgaaguccuc       60

acaccccuca aaugguacca aaacaugauc cgccaccccu acaccucaua cggcuacgaa      120

cccaugggcg gcuggcucca ccaccaaauc auccccgucg ucucccaaca aacaccccaa      180

ucacacgcac uccaacccca ccaccacauc cccauggucc ccgcccaaca acccggcauc      240

ccccaacaac ccaugaugcc acuccccggc caacacucaa ugacccccac ccaacaccac      300

caacccaacc ucccacuccc cgcacaacaa cccuuccaac cacaacccgu acaaccccaa      360

ccccaccaac cacuccaacc ccaauccccc augcacccca uccaaccccu acucccccaa      420

ccaccccuac ccccaauguu cucaaugcaa ucccuccucc ccgaccuccc ccucgaagca      480

uggccagcca cagacaaaac caaacgcgaa gaagucgacu aa                         522


<210>  926
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  926
augccaggcg uugcaagacu accacuacuc uuaggacuac uacuacuacc gcgaccagga       60

cgaccccucg accuagcaga cuacaccuau gaccucgccg aagaagauga uagcgaaccg      120

cuaaauuaca aagacccgug uaaagcagca gcuuuucuag gcgacauagc ccuggacgag      180

gaagaccuuc gggcguucca aguacaacag gcaguagauu uacgccgaca cacggcucga      240

aaaucaucaa ucaaagcagc cguuccagga aacacgucaa ccccaagcug ucagucaaca      300

aaugggcaac cccaacgcgg agcgugcgga cgauggcgag gccgcagcag gucccgcaga      360

gcagccaccu cccgccccga aagagucugg cccgauggag uaauaccguu cguaauaggc      420

ggcaauuuca ccggauccca gcgcgcgguc uuccgccaag ccaugagaca cugggagaaa      480

cauaccugcg ugacauuccu cgaaagaaca gacgaagacu cauacauagu auucaccuac      540

cgaccgugcg gcugcugcag cuacguaggc cgcagaggcg gcgggccaca agcgaucagc      600

aucggcaaaa acugcgacaa auucggaaua gucguccacg aacucggcca cguaguaggc      660

uucuggcacg agcacacccg accugaccga gaccgacacg ucagcaucgu aagagaaaac      720

auacaaccag ggcaagaaua caacuuccug aaaauggagc cccaagaagu ggaauccuua      780

ggagaaaccu acgacuuuga cucaaucaug cacuacgcaa ggaacacauu cucacgagga      840

auauuccucg acacaauagu ucccaaguac gaagugaacg ggguuaaacc uccgauuggc      900

caaaggacaa gacuaucaaa gggcgacauc gcacaggcac gaaaacugua caaaugcccc      960

gcaugcgggg agacacuaca agacagcacc gggaacuucu caaguccgga auacccaaac     1020

ggauacagug cucacaugca cugcguaugg cggauaagcg ucaccccggg cgagaaaaua     1080

auacuaaacu ucacaagucu ggaccuauac cggagccgcc uuugcuggua cgauuacgua     1140

gaaguccgcg acggauucug gcgcaaagcg ccacugaggg gacgcuucug cggaucaaaa     1200

cucccggaac cgauaguauc aaccgacuca cgccucuggg ucgaguucag aagcagcuca     1260

aacugggucg gaaaaggauu cuuugcagug uacgaagcua ucugcggagg agacguaaag     1320

aaagacuaug ggcacauaca aagccccaac uaccccgacg acuaccgccc uagcaaaguu     1380

ugcaucuggc gcauacaagu cagcgaaggc uuccacgucg gccugacauu ccagaguuuc     1440

gaaauagaac gccaugacag cugcgccuac gauuaccucg aaguccgcga cggccacucg     1500

gaaagcagca ccuuaaucgg cagguacugc gguuacgaaa aaccagacga cauaaagagc     1560

accucgagcc gacucuggcu aaaauucgua agcgacggca gcauaaacaa agcgggcuuu     1620

gcaguuaacu ucuucaaaga aguggacgaa ugcuccaggc caaaccgagg cgggugcgaa     1680

caaagauguc uaaauacacu cggcagcuac aaaugcagcu gcgacccggg auacgaacuc     1740

gcccccgaca aaagaaggug cgaagccgcc ugcggagggu uccucacaaa acuaaacggg     1800

agcaucacuu caccgggaug gccaaaagaa uacccaccaa auaagaacug caucuggcaa     1860

cucgucgcac ccacccaaua ccgcaucagc cuacaauucg acuucuucga aaccgaaggc     1920

aacgacgucu gcaaauacga cuucguugaa guccgcuccg gacuaacagc agacagcaaa     1980

cuacacggua aauucugcgg cuccgaaaag ccagaaguca uaacaagcca auacaacaau     2040

augagagucg aguucaagag cgacaacacc gucagcaaaa agggauuuaa ggcacacuuc     2100

uucucagaca aagacgaaug cucaaaagac aacggcggcu gccaacaaga cugcguuaac     2160

acauucggcu cauacgaaug ccaaugcaga ucagguuucg ugcugcacga caacaaacac     2220

gacugcaaag aagccggcug cgaccauaaa guuaccagca ccaguggaac cauaacaagc     2280

cccaacuggc cagacaaaua cccaucgaag aaagaaugca cgugggcuau cuccagcaca     2340

cccgggcacc gggucaaacu caccuucaug gaaauggaua ucgaaagcca accggaaugc     2400

gcauacgacc aucuagaagu cuuugacggc cgagacgcca aagccccagu acucggcaga     2460

uucugcggau ccaagaaacc agaaccagua cucgcgaccg ggagccgaau guuccuccgc     2520

uucuacagcg acaacuccgu gcaacgcaaa ggcuuccaag ccucccaugc gacggaaugc     2580

ggcggacaag uucgcgcgga cgucaaaacc aaagacuuau acagccaugc acaguucggu     2640

gacaacaauu accccggagg cguagacugc gaauggguca uaguagccga agaaggauac     2700

ggcgucgagc ucguauucca gacauucgaa guagaagaag aaaccgacug cggcuacgau     2760

uacauggaac uuuucgacgg guacgacagc acagcgccac gccucggacg cuacugcgga     2820

ucaggcccgc cagaagaagu auacagcgca ggcgacuccg uccuagucaa auuccauucu     2880

gaugacacca ucacaaagaa aggcuuccac uugagauaca caaguacaaa auuccaagac     2940

accuuacauu caagaaaaua a                                               2961


<210>  927
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  927
auggucgccg gaacucgcug ccuccuagcc cuccuacucc cccaaguacu acucggcggc       60

gccgccggcc ucguucccga acucggacga cgaaaauucg ccgccgcauc cucuggaagg      120

cccagcuccc aacccuccga cgaaguucuc uccgaguucg aacuccgccu ccucucaaug      180

uucggccuca aacaacgccc cacaccauca cgcgacgcag ucgucccgcc cuacaugcuc      240

gaccuauacc gucgucacuc aggccaaccc ggaucccccg cccccgacca ccgucucgaa      300

cgcgcagccu cgcgcgccaa cacaguccgc uccuuccacc acgaagaauc ccucgaagaa      360

cuacccgaaa ccuccggcaa aacaacccga cgcuucuucu ucaaccucag cuccaucccc      420

acagaagagu ucauaaccuc cgccgaacua caaguauucc gcgaacagau gcaagacgcc      480

cucggaaaca acagcucauu ccaccacaga aucaacauuu acgaaauaau caaacccgcc      540

accgcgaaca gcaaauuucc cgucacccgu cuccucgaca cccgccucgu caaccaaaac      600

gccucccgcu gggaaucuuu ugacguaaca cccgcaguca ugcgcuggac agcacaaggc      660

cacgccaacc acggauucgu cguagaagua gcccaccuag aagaaaagca aggaguaucc      720

aaacgucacg uacgaauauc acgcucccua caccaagacg aacacuccug gucccaaauc      780

cgaccccuac ucgucaccuu cggccacgac ggaaaaggac acccccuuca caaaagggaa      840

aaacgccaag ccaaacacaa acaacgcaaa cgacucaaau ccucaugcaa aagacacccc      900

cucuacguug auuucucaga cgucggcugg aacgacugga ucguagcccc acccggcuac      960

cacgccuucu acugccacgg cgaaugcccc uucccccucg cagaccaccu uaauucaacc     1020

aaccacgcaa ucguccaaac ccucgucaac uccgucaacu caaaaauccc caaagccugc     1080

ugcgucccca ccgaacuauc agccaucucc auguuauacc uagacgaaaa cgaaaaagug     1140

guccucaaaa acuaccaaga cauggucguc gaagguugcg gcugccgaua a              1191


<210>  928
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  928
augauacccg gcaaccgcau gcucaugguc guccuccucu gccaaguacu ccucggagga       60

gccucacacg ccucacucau accagaaacu ggcaaaaaaa aagucgcuga aauccaaggg      120

cacgccggcg gccgccgcuc cggccaaucc cacgaacuuc uuagagacuu cgaagccacc      180

cuacuccaaa uguucggacu ccgccgccgc ccccaacccu ccaaaucugc aguuauaccc      240

gacuacaugc gcgaccuaua ccgucuacaa ucaggcgaag aagaagaaga acaaauccau      300

aguaccggcc ucgaauaccc cgaacgcccc gccucccgcg caaauacagu ccgcucauuc      360

caucacgaag aacaccucga gaacaucccc ggaacguccg aaaacuccgc cuuccgauuc      420

cucuucaacc uaucauccau ccccgaaaac gaagucaucu ccuccgccga acuccgccuu      480

uuccgcgaac aagucgacca aggccccgac ugggaacgcg gcuuccaccg cauaaacauc      540

uacgaaguaa ugaaaccacc cgccgagguc guccccggac accuuaucac acgccuccuc      600

gacacccgac uaguccacca caacgucacc cgaugggaaa ccuucgacgu aucccccgca      660

guccuccgcu ggacccgcga aaaacaaccc aacuacggac ucgccauaga aguuacacac      720

cuccaccaaa cccgaacaca ccaaggccaa cacguccgaa ucucccgcuc ccucccacaa      780

ggcuccggca acugggccca acuccgcccc cuccucguaa ccuucggaca cgacggacgc      840

ggacacgccc ucacccgacg ccgccgagcc aaacgcuccc ccaaacacca cucacaaaga      900

gccaggaaaa aaaauaaaaa uugccgccgc cacucacucu acguagacuu cagcgacguc      960

ggcuggaacg acuggauagu cgcccccccc ggcuaccaag cauucuacug ccauggcgac     1020

ugccccuucc cacucgccga ucaccuaaac agcaccaacc acgccauagu ccaaacccua     1080

guaaacuccg ucaacuccag cauacccaag gcaugcugcg uacccacaga acugagcgca     1140

aucuccaugu uauaccucga cgaauacgac aaaguaguac ucaaaaacua ccaagaaaug     1200

guaguagaag gaugcggcug ccgcuaa                                         1227


<210>  929
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  929
augcccggau uaggucgccg agcacagugg cucugcuggu gguggggacu ccucuguagc       60

ugcugcggac cccccccccu acgcccaccu cuccccgccg cugccgccgc cgccgccggc      120

ggccaacuac ucggagacgg cggaucaccc ggccgaacug aacaaccacc ccccucaccc      180

caauccucaa gcggguuccu cuaccgucgc cugaaaaccc aagaaaaacg cgaaaugcaa      240

aaagaaaucc uauccguccu cggccucccc caccgccccc gcccccuaca cggacugcaa      300

caaccccagc caccagcccu acgucaacaa gaagaacagc agcaacaaca acaauuacca      360

agaggagaac cacccccugg ccgacugaaa uccgccccac uauucaugcu cgaccuauac      420

aacgcacuca gcgcagacaa ugacgaagac ggcgcaucag aaggagaaag acaacaauca      480

uggccacacg aagcagccuc aagcucccaa cgaagacaac caccacccgg agcagcgcac      540

ccccuaaacc gcaaaucccu acuggccccc ggauccggca gcggcggcgc cuccccacua      600

accagcgccc aagacucugc auuccuuaac gacgcagaca uggucauguc auucguuaac      660

cuggucgaau acgacaaaga auucucgccc cgacaacgac aucacaagga auucaaauuc      720

aaccucagcc agauacccga aggcgaagua gucaccgccg ccgaguuccg caucuauaaa      780

gacugcguca ugggaucauu caaaaaccaa acauuccuaa ucuccaucua ccaaguacuc      840

caagaacacc agcaccgcga cagcgaccuc uuccuauuag acacccgcgu agucugggcc      900

ucagaagaag gcuggcucga auucgacaua acugccaccu caaaucuuug ggucgucaca      960

ccacaacaca acaugggccu ccaacucucc guagucaccc gugacggagu ccacguacac     1020

ccccgagcug ccggccucgu cggacgagac ggccccuacg acaaacaacc cuucaugguc     1080

gcauucuuca aagucuccga aguccacguc cgaaccaccc gcucagccuc cucccgucgc     1140

aggcaacaau cccgaaaccg auccacacaa ucccaagaug uagccagagu auccuccgcc     1200

uccgacuaua acuccuccga acucaaaaca gcaugccgca aacacgaacu cuauguaucc     1260

uuccaagacc uuggauggca agacuggauc aucgccccaa aaggauacgc cgccaacuac     1320

ugcgacggcg aauguucauu cccucuaaac gcccacauga acgcaaccaa ccacgccauc     1380

guacaaacac uuguccaccu caugaauccc gaguacgucc ccaaacccug cugcgcaccc     1440

accaaacuca acgccauauc agucuuauac uucgacgaca acucaaacgu aauccugaaa     1500

aaauaccgca acauggucgu ucgcgcaugc ggcugccacu aa                        1542


<210>  930
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  930
augcacgucc guucccugag agccgccgcc ccccacucgu uugucgcccu augggcaccc       60

cuauuccucc uucgaucagc acuugcagac uucucccuug acaacgaagu ccacucgucc      120

uucauccacc gccgccucag aucacaagaa cgacgagaaa ugcaacgcga aauacuuagc      180

auccuaggcc ucccccaccg uccccgacca caucuccaag gcaaacacaa cucagcccca      240

auguucaugc ucgaccucua caacgccaug gccgucgaag agggcggcgg acccggcggu      300

caaggcuucu ccuacccaua caaagccguc uucagcacuc aaggaccacc ccucgcuucc      360

cuucaagacu cccacuuccu aaccgacgca gauaugguca uguccuucgu caaccuaguc      420

gagcacgaca aagaauucuu ccacccccgc uaccaccacc gagaauuccg cuucgaccuc      480

uccaaaauac ccgaaggcga ggccgucaca gcugccgaau uccgcaucua caaagacuac      540

auccgcgaac gcuucgacaa cgaaaccuuc aggaucucag ucuaucaagu ccuacaagaa      600

caucucggcc gcgaauccga cuuauuccuc cuagacucac gcacccucug ggccucagaa      660

gaaggauggc ucguauucga caucacagcc acaucaaacc acugggucgu caacccccgc      720

cacaaccucg gccugcagcu aucaguagaa acccucgacg gacaauccau caaccccaaa      780

cucgccgguc ucaucggccg acacggccca caaaacaaac agcccuucau ggucgccuuc      840

uucaaagcca ccgaagucca cuuccgaagc auccgcucca ccggauccaa acaacgcucc      900

cagaaucguu ccaaaacccc gaaaaaccaa gaggcccuac gcauggccaa cgucgcagaa      960

aacuccucau cagaccaacg ccaagccugc aaaaaacacg aacuauacgu cuccuuccgc     1020

gaccucggau ggcaagacug gaucaucgca ccagaaggcu acgccgccua cuacugugaa     1080

ggagaaugcg ccuuuccucu caacuccuac augaacgcca ccaaccacgc aauuguacaa     1140

acccuaguuc acuucaucaa cccagaaaca gucccaaaac ccugcugugc ccccacacaa     1200

cuaaacgcaa uauccguccu cuacuucgac gauuccucga acguuauccu caaaaaauac     1260

cgcaacaugg uaguccgagc cugcggaugc cacuga                               1296


<210>  931
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  931
augaaagccu cagccgcccu ccucugccuc cuccucacag cagccgccuu cuccccccaa       60

ggccucgccc aaccagucgg caucaacacc uccacaaccu gcugcuaccg cuucauaaac      120

aaaaaaauac ccaaacaacg ccuagaaucc uaccgcagaa ccacauccuc acacugcccc      180

cgcgaagccg ucaucuucaa aaccaaacua gacaaagaaa ucugcgccga ccccacccaa      240

aaaugggucc aagacuucau gaaacaccua gacaaaaaaa cacaaacccc caaacucuaa      300


<210>  932
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  932
augcuguuaa cgcuaaucau ccuacuacca gucguaagca aguucucuuu ugucucccug       60

agcgcgcccc agcauugguc cugcccagaa ggcacccucg caggcaaugg aaacagcaca      120

ugcguaggcc cggcuccauu ccuaaucuuc agccauggca acagcaucuu uagaaucgac      180

accgagggca ccaacuacga acaacucgug guagaugccg gagugagcgu aauaauggac      240

uuccacuaca acgaaaaacg cauauauugg gucgaccuag aacggcagcu ccuccaaagg      300

guauuucuca acggaucccg acaggagcgg gugugcaaua ucgagaaaaa cgucuccgga      360

auggcaauca acuggaucaa cgaagaaguc aucuggagca aucagcagga aggaaucaua      420

acagucacug auaugaaggg caauaacucc cacauacuac ucucagcacu aaaauacccc      480

gccaacguag caguagaucc uguggaacgc uucaucuucu ggagcucaga gguagccggu      540

agccucuaca gagcggaucu ugacggagug ggugugaaag cacuuuuaga aacaagcgag      600

aaaauaaccg caguaucccu ugacgugcuc gacaaacgac uauuuuggau ucaguacaau      660

cgggaaggcu cgaacucccu aauaugcucg ugcgauuacg acggcggaag cguacacaua      720

agcaagcacc ccacgcagca caaccucuuu gcaauguccc uguucgguga ccgaaucuuc      780

uacuccaccu ggaaaaugaa gaccauaugg aucgcgaaca aacauacagg gaaagauaug      840

gucagaauca accuacacag cuccuucguc ccccuaggag aacuaaaggu cguacaucca      900

cucgcccaac ccaaagcgga agacgacacc ugggaaccgg aacaaaaauu gugcaaauua      960

agaaagggua auugcuccag cacugucugc gggcaagacc uccaaucaca ccucugcaug     1020

ugcgcggaag gguaugcccu gagccgggac cgcaaauauu gcgaagacgu caaugaaugc     1080

gccuucugga accacggaug uacgcuuggu ugcaaaaaca cacccgggag cuacuacugu     1140

accugccccg uaggcuucgu ccuacugccg gacggcaagc ggugucauca gcuagucagu     1200

ugcccacgca acguuucaga augcagccac gacugcgucc uaacauccga gggaccacuc     1260

uguuucugcc cagaaggcuc agugcuagaa agagacggaa aaacaugcag cgggugcuca     1320

agcccagaua auggcgggug cucgcaacua ugugugccac uauccccugu cuccugggaa     1380

ugcgacugcu uccccggaua cgaucuccaa cucgacgaaa agucaugcgc cgccaguggc     1440

ccccaacccu uucuucuauu cgccaacagc caagacauuc gccacaugca cuucgacgga     1500

acagacuacg gaacccucuu aucucaacag augggcaugg uuuacgccuu agaucacgac     1560

ccuguggaaa acaaaauaua cuucgcccac acagcacuaa aauggaucga aagagcaaau     1620

auggacggcu cacaacgaga acgccucaua gaagagggcg uagacguacc cgaaggccua     1680

gcgguugacu ggauaggcag aagguucuac uggacugacc gaggcaaguc ucugauaggg     1740

cgcucggacc ugaacggcaa acgcuccaaa aucauaacaa aggagaacau cucccaaccc     1800

agaggaaucg caguucaccc aauggccaaa cgacuguucu ggaccgacac uggaaucaac     1860

ccgcggaucg aaucuuccag ucuacagggg cuggggcguc ucguuauugc aucgagcgac     1920

cugauauggc ccagcggcau aacgauagac uuccugacag acaaacugua cuggugcgac     1980

gcaaaacaaa gcgugaucga aauggccaau cucgacggau caaaaagacg cagacucaca     2040

cagaacgacg ugggccaccc uuucgcugua gccguauucg aagacuacgu cugguucuca     2100

gacugggcca ugcccagcgu aaugcgaguu aacaaacgca ccgguaaaga cagaguccgu     2160

cuccaaggcu caaugcuaaa gccuaguucc cuuguaguag uacauccacu agcuaaaccc     2220

ggugcagacc cgugccuaua ccagaacggu ggaugugaac acauuugcaa aaagcgauug     2280

ggaaccgccu ggugcagcug uagagaagga uucaugaaag cgagugacgg aaaaacaugc     2340

cucgcacucg acggccacca gcuccuagcc ggaggggaag uagaucucaa aaaccaagug     2400

acgcccuuag acauacuaag caaaaccaga guaucggagg acaacaucac ggagagccaa     2460

cacaugcuug uagcugaaau caugguaagc gaccaagacg auugcgcgcc agucggaugc     2520

agcauguacg cacggugcau cuccgaaggu gaagaugcua ccugccagug ccuaaaagga     2580

uuugcgggag acggcaaacu auguagcgau aucgacgaau gcgaaauggg agucccuguc     2640

uguccgccag caagcuccaa augcaucaac accgagggag guuacguaug ccgaugcucc     2700

gagggauauc aaggagacgg cauacacugc cucgacauag acgaaugcca acugggagag     2760

cacuccugcg gcgaaaacgc aagcuguacc aacacagagg gcggcuacac augcaugugc     2820

gccggccgcc uaucugaacc cggacucauc ugccccgacu cgaccccucc uccgcaccua     2880

cgugaggacg accaccauua cagcgugcga aauuccgacu cggagugccc ccuaucccac     2940

gacggauacu gccuucauga cggcgucugc auguauaucg aagcccuaga caaauacgcg     3000

uguaauugcg uugucggcua caucggggaa cgaugccagu accgcgaccu aaaauggugg     3060

gaacuaaggc acgccgggca uggccagcag cagaaaguca uagucguggc agucugcgua     3120

guggugcucg ucaugcuacu ccuacuauca cucuggggag cgcacuacua ccgcacccaa     3180

aaacuucuaa gcaaaaaucc caaaaaccca uacgaggaau caagccggga uguucgaucg     3240

aggcgaccag cggacacaga agauggcaug agcucgugcc cgcagcccug guucguggug     3300

aucaaggagc aucaagaccu gaaaaacggg ggacaaccag uagccgguga agacggccaa     3360

gcagccgacg guagcaugca gccaaccuca uggagacaag aaccacaacu cugcgguaug     3420

ggcacagaac agggcugcug gauucccguc ucauccgaca agggcagcug cccccaagua     3480

auggagcgau ccuuccacau gccaagcuac ggaacgcaga cccuagaagg cgggguagaa     3540

aagccgcauu cccugcuguc ugccaacccc cuguggcaac agcgcgcacu cgacccaccu     3600

caccagaugg aacucacaca auga                                            3624


<210>  933
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  933
augaccgccg gccgacgaau ggaaaugcuc ugcgccggcc guguccccgc acuucuccuc       60

ugccucggau uccaccuacu ccaagccguc cucuccacca ccgucauccc cucaugcauc      120

cccggagaau ccuccgacaa cugcaccgcc cuaguacaaa cagaagacaa cccccgcguc      180

gcacaaguuu ccaucaccaa augcuccuca gacaugaaug gcuacugccu ccacggacaa      240

ugcauauacc uagucgacau gucccaaaac uacugccgcu gugaagucgg auacacaggc      300

guccgcugcg aacacuucuu ccucaccguc caccaacccc uauccaaaga auacgucgcc      360

cucaccguca uccucauaau ccuauuccuc aucacaguug ucggcuccac cuacuacuuc      420

ugccgcuggu accgcaauag aaaauccaaa gaaccaaaaa aagaauacga acgcguaacc      480

ucaggcgacc ccgaacuccc acaagucuaa                                       510


<210>  934
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  934
auggcagaag gcgaaauaac cacauucacc gcccucaccg aaaaauucaa ccucccccca       60

ggcaacuaca aaaaaccaaa acuccuauac ugcuccaacg gcggacacuu ccuccgcauc      120

cuccccgacg gcacagucga cggaaccaga gaccgcucag accaacacau ccaacuccaa      180

cucuccgccg aaucagucgg agaaguauac aucaaaagca ccgaaaccgg acaauaccua      240

gccauggaca ccgacggcuu acucuacggc ucacaaaccc ccaacgaaga augccucuuc      300

cucgaacgcc ucgaagaaaa ccacuacaac acauacaucu ccaaaaaaca cgcagaaaaa      360

aacugguucg ucggccucaa aaaaaacggc uccugcaaac gcggcccccg cacccacuac      420

ggccaaaaag ccauacucuu ccucccccuc cccgucucau cagacuaa                   468


<210>  935
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  935
augguggggg uagggggagg ggauguggag gauguaacgc cgaggccagg gggaugccaa       60

auaaguggaa gaggggccag gggauguaac gggaucccgg gagcggcagc gugggaggca      120

gcgcugccga gaaggagacc gagaaggcac ccgaguguga acccgaggag cagggcggca      180

gggagcccga gaacaagagg gagaaggaca gaggaaagac caucggggag cagguugggg      240

gaucgagggc gaggaagggc gcugccggga gggagauugg gagggagagg gagggggaga      300

gcgccagaga gggugggagg aagggggaga ggaagaggga cggcggcacc gagggcggcg      360

ccggcggcaa ggggaagcag accagggccg gcgggaacga uggcggcggg gagcauaacg      420

acgcuaccag cauugcccga agacggagga ucgggcgcau ucccgccagg gcauuuuaaa      480

gauccgaaga ggcuguacug uaaaaaugga ggguucuuuc ugagaauaca uccggaugga      540

cggguagaug gagugagaga gaagagugac ccgcacauaa aguugcaacu gcaagcggaa      600

gagagaggag uagugagcau aaaaggggua ugugccaaca gauaucuagc aaugaaggaa      660

gauggaaggc uacuggcaag caagugugua acggacgagu gcuuuuucuu cgaaaggcua      720

gagaguaaca acuauaacac guacagaagc aggaaauaua caaguuggua uguggcgcua      780

aagaggacgg gacaauacaa gcuggggagc aagacagggc cggggcaaaa ggcaauacug      840

uuuuuaccaa ugagugcgaa gaguuaa                                          867


<210>  936
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  936
augcacaaau ggauccuaac cuggauccua cccacccuuc ucuaccgauc cugcuuccac       60

aucaucugcc uaguaggaac caucucacuc gcaugcaacg acaugacacc cgaacaaaug      120

gccaccaacg ucaacugcuc cuccccagaa cgccacacac gcagcuacga cuacauggaa      180

ggcggagaca uccgcguccg ccgccucuuc ugccgaacac aaugguaccu ccgcaucgac      240

aaacgcggca aaguaaaagg cacacaagaa augaaaaaca acuacaacau cauggaaaua      300

cgcacaguag ccgucggaau cguagcaauc aaaggcgucg aauccgaauu cuaccucgcc      360

augaacaaag aaggcaaacu auacgccaaa aaagaaugca acgaagacug caacuucaaa      420

gaacucaucc uagaaaacca cuacaacaca uacgcaucag ccaaauggac ccacaacgga      480

ggcgaaaugu ucgucgcccu caaccaaaaa ggcauccccg ucagaggcaa aaaaaccaaa      540

aaagaacaaa aaacagcaca cuuccucccc auggccauca ccuga                      585


<210>  937
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  937
augaaacuac uccccuccgu cguccuuaaa cucuuccucg ccgccguacu cuccgcacuc       60

gucacaggcg aaucacucga acgacuccgc cgaggccucg ccgcaggcac cucaaacccc      120

gaccccccaa ccguguccac agaccaacua cuaccacucg gcggaggacg cgaccgcaaa      180

guccgcgacc uccaagaagc agaccuagac cuccuccgag ucacccucuc cuccaaaccc      240

caagcccuag ccacccccaa caaagaagaa cacggcaagc gaaaaaaaaa aggcaaaggc      300

cuaggcaaaa aacgcgaccc augccuacgc aaauacaaag acuucugcau ccacggcgaa      360

ugcaaauacg uaaaagaacu ccgagcccca ucaugcaucu gccaccccgg cuaccacgga      420

gaacgcugcc acggccuauc ccuacccguc gaaaaccgcc ucuacaccua cgaccacaca      480

acaauccucg ccgucgucgc agucguccuc ucauccguau gccuccucgu caucgucggc      540

cuacucaugu uccgcuacca ccgacgaggc ggcuacgacg ucgaaaacga agaaaaaguc      600

aaacucggaa ugacaaacuc ccacuaa                                          627


<210>  938
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  938
auguggguca ccaagcuacu ccccgcucuc cugcuacaac acguccugcu ccaccuccua       60

cuccucccca uagccauacc auacgccgaa ggacaacgca agcgccguaa uacaauacau      120

gaguucaaga aaagcgccaa aaccacccuu aucaaaaucg accccgcccu aaaaaucaag      180

accaaaaagg ugaacaccgc cgaccaaugc gccaacagau gcaccagaaa caagggccuc      240

cccuucacau gcaaagccuu cguauucgac aaggcccgca aacaaugccu augguuccca      300

uucaacucca uguccuccgg cgucaagaaa gaguucggcc acgaauuuga ccucuacgaa      360

aauaaagacu acauccgaaa cugcaucauc ggcaaaggac gcucauacaa aggcaccgua      420

uccaucacca aaucaggcau aaaaugccaa cccuggagcu caaugauccc ccacgaacac      480

ucauuucuac cauccuccua ccgaggcaaa gaccuccagg aaaauuacug caggaacccg      540

cgcggggaag aaggcggacc cuggugcuuu accuccaacc ccgaaguacg guacgaaguc      600

ugcgacauac cccaaugcuc cgaaguagaa ugcaugacau gcaacggaga auccuaucgg      660

ggccucaugg aucacacaga aucagguaaa aucugccagc gcugggacca ccagaccccu      720

caccgccaua aauuccuccc agaacgcuac ccagacaaag gguucgacga caacuacugc      780

agaaacccug acggccagcc acgcccaugg uguuacacac uagaccccca cacccgaugg      840

gaauacugcg ccaucaaaac augugcagac aauacaauga augacaccga cgucccacuc      900

gaaaccaccg aaugcaucca agggcaggga gaaggauacc gaggcacggu caacaccauc      960

uggaacggca uacccugcca acggugggac agccaauauc cgcacgaaca cgacaugacu     1020

ccagaaaacu ucaaaugcaa agaccucaga gagaacuacu gcagaaaucc cgacggaucc     1080

gaaucacccu ggugcuucac cacggacccc aacauccgcg uaggcuacug cucacaaaua     1140

ccaaacugcg auaugagcca cggucaagac ugcuaucgcg gcaacggcaa aaacuacaug     1200

ggaaaccucu cacagacccg cucaggccua acguguagca ugugggacaa aaacauggag     1260

gaccuucauc ggcacaucuu cugggaaccc gacgcaucca aacuuaacga gaacuacugc     1320

cgaaacccag acgacgacgc ccacgggcca uggugcuaca caggcaaccc acucaucccg     1380

ugggacuauu gccccauaag ccgcugcgag ggcgacacaa ccccaacaau cgugaaccug     1440

gaccacccug ucaucucgug cgcaaaaaca aaacagcuuc gggucgucaa cggcauccca     1500

acacgaacaa acauagggug gauggucucu cuacgcuaca gaaacaaaca caucugcggc     1560

ggcucacuca ucaaagaaag cuggguccuc acagcucgcc aaugcuuccc aucaagagac     1620

cucaaagauu acgaagccug gcuaggcaua cacgacguac auggaagggg agacgaaaaa     1680

ugcaaacaag uacuuaacgu aagccaacuc gucuauggcc cagaaggaag cgaccucguc     1740

cucaugaaac uagcacgccc agccguccuc gacgacuuug uaagcaccau agaccucccc     1800

aacuauggcu gcaccauccc agagaaaacg aguugcucag ucuacggcug gggauacacg     1860

ggacugauca auuacgacgg acuacuccgg gucgcacacc ucuacaucau gggcaacgaa     1920

aaaugcuccc aacaccaccg cggcaaagua acucucaacg aaagcgaaau cugcgccgga     1980

gccgagaaaa ucggcucagg cccaugcgaa ggcgacuacg gcggaccccu uguuugcgaa     2040

caacacaaaa ugaggauggu acucggcgua auaguucccg gcagggggug cgccauccca     2100

aaccgacccg gaauauuugu cagaguagca uacuacgcga aauggauuca caaaaucaua     2160

cuaaccuaca aaguccccca gucguaa                                         2187


<210>  939
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  939
auggccaaag ccgccgcaau cggcauagac cucgguacga cguacagcug cguaggcguc       60

uuccaacacg gcaaggugga aauaaucgcu aacgaccaag gcaacagaac cacaccgucg      120

uacgucgcau ucaccgacac cgaacgacuc aucggggacg cggccaaaaa ccaagucgca      180

cuaaaccccc aaaacacagu guucgacgcc aaacgacuca ucgggagaaa auucggcgac      240

cccguagucc aguccgacau gaaacacugg cccuuccaag uaaucaacga cggagauaaa      300

cccaaaguac aagucagcua caaaggagag accaaggccu ucuacccaga ggaaaucuca      360

agcauggugc ugacaaaaau gaaagaaauc gcagaagccu accuaggaua cccagucacg      420

aacgccguca ucaccguccc cgcauacuuc aacgacagcc aaagacaggc caccaaagac      480

gccggaguca ucgcaggacu caauguccua cgaauaauaa acgagccaac cgcagccgcc      540

auagcauacg gacucgaccg aacaggcaaa ggagaacgca acguccuaau cuucgaccuc      600

gggggcggga ccuucgacgu cuccauccua acaauagaug acggcaucuu cgaagugaaa      660

gccaccgccg gcgacacaca ccucggggga gaagacuucg acaaccgccu cguaaaccac      720

uucgucgaag aauuuaagcg aaaacacaag aaagacauca gccaaaauaa gcgcgcggug      780

cgacgccuga gaaccgcaug cgagcgagcc aaacgaacgc ucucauccuc aacccaagcg      840

ucacucgaaa ucgacucacu cuucgaggga aucgacuucu acaccucaau cacgcgagcc      900

cgcuucgaag aauuaugcuc agaccucuuc cgaucaacac uagaacccgu cgaaaaagcc      960

cucagagaug caaaacugga caaagcacaa auccaugacc uuguccuagu aggaggcuca     1020

accaggaucc ccaaaguaca aaaacugcuc caagacuucu ucaaugggcg agaccucaac     1080

aaguccauaa accccgacga agcagucgca uacggggcag caguccaagc agcaauauua     1140

augggcgaca agucggaaaa cguccaagac cuccuacuac uagacgucgc gccacuaagu     1200

cuagggcucg aaaccgcggg aggcgucaug acugcccuaa ucaaacgcaa cuccaccauc     1260

cccacaaaac aaacccaaau auucaccaca uacuccgaca accaaccagg aguacugaua     1320

caaguauacg aaggcgaacg agccaugacc aaagacaaca accuacuagg acgcuucgaa     1380

cucagcggaa ucccacccgc ccccagagga guaccccaaa uagaagucac auucgacauc     1440

gacgcaaacg gcauccuaaa cguuacagcg accgacaaau ccaccggaaa agcaaacaag     1500

auaacgauca caaacgacaa aggcagacuc uccaaagagg agaucgagag aaugguccaa     1560

gaagcagaga aauacaaagc agaagacgaa guccaacgug aacgcgucag cgccaagaac     1620

gcacucgagu cguacgccuu caacaugaaa agcgccgucg aggacgaagg acucaagggg     1680

aaaaucucag aagccgacaa aaagaaagua cucgacaaau gccaagaagu aaucagcugg     1740

cuagaugcca acacacucgc cgaaaaagac gaguucgaac acaaacgcaa agaauuagaa     1800

caagucugua accccaucau cuccggacuc uaccaaggcg caggcggacc aggccccggc     1860

ggcuuuggcg cacaaggccc caaaggcggc agcgguuccg gccccacaau agaagaagua     1920

gacuga                                                                1926


<210>  940
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  940
auggcaaaag cggcagcaau cggaaucgac uuaggcacca ccuacucgug cgugggaguc       60

uuccaacacg gcaaggugga aaucaucgca aacgaccagg gcaaccgcac cacccccagc      120

uacguagccu ucacagacac cgaacgccug auaggagacg cagcgaaaaa ccaggucgca      180

cucaacccac aaaacacagu cuuugacgca aaacggcuca uaggaagaaa auucggcgac      240

ccgguggucc agagcgacau gaaacacugg cccuuccagg ugauuaacga cggagacaag      300

ccgaaagucc aagucucgua caaaggcgaa accaaggcau ucuacccgga agaaaucucc      360

uccauggucc uaaccaaaau gaaagaaaua gccgaagcau accucggcua ccccgucacc      420

aacgcgguaa uaaccguccc cgcauacuuu aacgacaguc aacgucaggc caccaaagac      480

gcagggguca uagcagggcu caacguccuc cgaaucauca acgaacccac cgcagcagcc      540

auagcauacg gucucgaccg cacaggcaaa ggcgaacgaa acguccuaau cuucgaccua      600

ggugggggca ccuucgacgu cucaauccua acaauagacg acggcauauu cgaaguaaag      660

gcaaccgcag gcgacaccca ccuaggcggc gaagacuucg auaaccggcu cgugaaccac      720

uucgucgaag aguucaaacg caagcacaag aaagacauau cgcaaaacaa acgagcagua      780

aggcgacucc gaaccgcgug cgaacgagca aaaagaaccc uaagcucgag cacgcaggcc      840

agccucgaaa uagacucccu cuucgaaggg aucgacuucu acacaucaau aacacgagca      900

cgauucgaag aacucugcag cgaucuauuu cgcucaaccc ucgagccggu cgaaaaagcc      960

cuccgcgacg cgaaacuaga caaagcccag auacacgacc uaguccuagu agggggauca     1020

accaggauac caaaaguaca aaaacuacuc caagacuucu ucaacgggcg cgaccugaac     1080

aaaucuauca acccagacga agccgucgcg uacggcgccg cuguccaagc cgcaauucug     1140

augggagaca aaagugaaaa cguacaagau cuccugcuac uagacguagc cccacuauca     1200

cugggauuag aaaccgcggg cggagucaug accgcccuaa uaaaaagaaa cucaacaauc     1260

ccaacgaaac aaacacaaau cuucaccacc uacagcgaca accaacccgg agugcucauc     1320

caaguguacg aaggcgaacg cgcaaugaca aaagacaaca accuccuagg aagauucgaa     1380

cuauccggca ucccaccagc cccacgcgga gucccacaga uagaagucac auuugacaua     1440

gacgcgaacg gaauacuaaa cguaacagcg accgacaaau cgacgggcaa ggcaaauaaa     1500

auaaccauca cgaaugacaa agggcgccua agcaaggaag agaucgaaag aauggugcag     1560

gaagccgaaa aguacaaggc cgaggacgaa guccaaagag aacgggucag cgccaaaaac     1620

gcacuagaau cguacgccuu caacaugaaa uccgcggucg aagacgaagg acucaaagga     1680

aaaauaagcg aagcugacaa aaagaaagua cucgacaaau gccaagaagu aaucuccugg     1740

cucgacgcaa acacauuagc cgagaaggac gaguucgaac acaaacgaaa agaacuugaa     1800

caaguaugca accccauuau uucaggccua uaccaaggag caggagggcc cgggcccgga     1860

ggcuucggcg cgcaaggccc aaaaggagga uccggaagcg gaccgacaau cgaagaaguc     1920

gacuga                                                                1926


<210>  941
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  941
auggcaaccg ccaagggcau cgccaucggg auagaccucg gaacaaccua cucaugcguc       60

ggagucuucc aacacggcaa aguggagaua aucgccaacg accaaggaaa ccgaacgaca      120

cccucauacg uggcguucac agauacagag cgguuaaucg gcgacgcagc caaaaaccaa      180

gucgccauga acccacaaaa cacggucuuu gacgccaaaa ggcuaauugg cagaaaauuc      240

aacgaccccg uaguccaggc cgacaugaaa cucuggcccu uccaagucau aaacgaaggc      300

ggcaaaccca aaguccuagu cucauacaaa ggcgaaaaca aagcauucua cccggaagaa      360

aucucgagca uggucuuaac aaaauuaaaa gaaacggccg aagcauuccu uggacacccc      420

gucacgaacg caguaaucac aguccccgca uacuucaacg acucccaacg ccaggcgaca      480

aaagacgccg gggucauagc cggccuaaac guucugagga uaaucaacga gccgaccgcc      540

gcagccauag cguacggacu ugacaaagga ggacaaggcg aacgccacgu acucaucuuc      600

gaccugggcg gcggcaccuu ugacgucucc aucuuaacca ucgacgacgg caucuucgaa      660

guaaaagcca cggccggaga cacacaccuu ggcggagaag acuucgacaa ccggcucguc      720

agucacuuug ucgaagaguu caagcgcaaa cacaagaaag auaucucgca aaacaaaaga      780

gcaguccgaa gacuccgcac cgccugcgaa cgcgccaaga gaacacucag cagcucaaca      840

caggcaaacc uggaaaucga cucacucuac gaaggcauag acuucuacac cucaauaaca      900

cgagcgcgcu ucgaagaacu augcgccgac cucuucagag ggacccugga accggucgaa      960

aaagcccucc gagacgccaa aauggacaaa gcaaaaaucc acgacauagu ccuaguaggu     1020

gggucaaccc gaauccccaa agugcaacga cuccuccaag acuacuucaa cgggcgcgac     1080

cucaauaaau caaucaaccc cgacgaagca guagcauacg gcgcagcagu ccaagcagcg     1140

auccuaaugg gggacaagag cgaaaaaguc caggaucucc uccuccuuga cgucgcaccu     1200

cuaucucuag gacuagaaac cgcagggggu guaaugacag cacucaucaa aagaaacuca     1260

acaauaccca ccaaacaaac acaaaucuuc acaaccuacu ccgacaacca accaggagua     1320

cuaauacaag ucuacgaagg ggaacgcgcc augaccaaag acaacaaccu ccugggccgu     1380

uucgaccuaa ccgguauccc accagcacca cgcggaguac cgcaaauaga agugacguuc     1440

gacauagacg caaacggaau ccucaacguc accgcgaccg acaaaucaac cggcaaagug     1500

aacaaaauca ccaucacaaa cgacaaaggg cgauuaagca aagaagaaau cgaacgaaug     1560

guccucgacg cagaaaaaua uaaggccgaa gacgaagucc aacgagagaa aauagccgcc     1620

aaaaacgcau uagaaucaua cgccuucaau augaaaagcg uaguaucaga cgaaggccua     1680

aaaggcaaaa ucagcgagag cgacaaaaac aagauacuag acaaaugcaa cgaacuccua     1740

agcuggcucg agguaaacca acucgcagaa aaggacgagu ucgaccacaa aagaaaagaa     1800

cuagagcaaa uguguaaccc aaucauaaca aaauuauacc aaggaggcug cacggggccc     1860

gccugcggaa caggcuaugu cccaggaaga cccgccaccg gccccacgau agaagaaguc     1920

gacuaa                                                                1926


<210>  942
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  942
augagcgccc ggggacccgc aaucggcauc gaccuaggaa ccacauacag cugcguaggc       60

guguuccaac acggaaaagu cgagauaauc gccaacgacc aaggaaaccg aaccacccca      120

ucauacguag cguucaccga caccgaaaga cucaucgggg augcagcgaa gaaccaggug      180

gcuaugaacc ccacaaacac aaucuucgac gccaaacgcc uaauagggag aaaauucgaa      240

gacgcaacag uccaaucaga caugaaacac uggcccuuca gggucgucuc agaaggagga      300

aaacccaaag uacaagucga auacaaaggc gaaacaaaaa cguucuuccc agaagagauc      360

ucauccaugg uccucacaaa gaugaaggaa auagccgaag ccuaccuagg cggcaaaguc      420

cacagcgcag ucauaaccgu accagcauac uucaacgaca gccaacggca agccacaaaa      480

gacgcaggaa ccaucaccgg guuaaacgua cuacgaauaa uaaacgaacc cacagcagca      540

gccaucgcgu acggccucga caagaaaggc ugcgccggag gcgagaaaaa cguacucauc      600

uucgaccucg gcggaggcac auucgacgua ucgauacuca caauagaaga cggcauauuc      660

gaagucaaau caaccgccgg agauacacac cuuggagggg aggacuucga caacagaaug      720

gugagccacc uagcagagga guucaaacga aaacacaaga aagacauagg acccaacaaa      780

agggccguac gcagacucag aacagcaugc gaaagagcca aacgaacacu aucauccucc      840

acacaggcca gcauagaaau agacucacua uacgaaggag ucgacuucua caccagcauc      900

acacgcgcca gauucgaaga acucaacgcc gaccuauucc gaggcacccu cgagccgguc      960

gagaaagcgc uccgagacgc aaaacucgac aaaggacaaa uacaagaaau aguccucguc     1020

ggaggcucca cccgaauccc uaaaauacaa aaacuacucc aagacuucuu caacggaaaa     1080

gaacuaaaca aaucaaucaa ccccgaugaa gccguugcau acggcgccgc uguccaagca     1140

gcaauccuaa uaggagauaa aagcgaaaac guacaagacc uccugcuacu agacgucacc     1200

ccacucucac ucggaaucga gaccgccggc gguguaauga ccccacucau aaaacgaaac     1260

accaccaucc ccaccaaaca aacacagacg uucaccaccu acuccgacaa ccaaucaucc     1320

gugcuagugc aagucuacga aggcgaaaga gccaugacca aagacaacaa ucuccucggc     1380

aaauucgacc ugacgggcau acccccagcc ccacgaggcg ucccccaaau cgaggucacc     1440

uucgacauag acgcgaacgg cauccucaac gucacugcug cagacaaauc gacaggaaag     1500

gaaaacaaaa ucaccaucac aaacgacaag gggcgccuca gcaaagacga caucgaccga     1560

augguacaag aagcagaacg cuacaagagc gaagacgaag ccaacagaga ccgcgucgcc     1620

gccaaaaacg cccucgaauc cuacacauac aacauaaaac aaaccgucga agacgaaaaa     1680

cuacgcggaa aaauaagcga gcaagacaaa aacaaaauau uagacaaaug ccaagaagua     1740

aucaacuggc ucgaccgcaa ccaaauggcc gaaaaagacg aauacgaaca caaacaaaaa     1800

gaacucgaac gaguaugcaa cccgauaauc aguaagcugu aucaaggagg cccaggaggc     1860

ggaagcggcg gcggagguuc gggcgcgucc ggaggcccaa caauagaaga agucgacuga     1920


<210>  943
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  943
augagcgugg uaggcauaga ccugggcuuc cagagcuguu augucgcagu agcccgcgca       60

ggcggcauag aaacaaucgc aaacgaguac agcgaccgcu gcacaccggc augcaucucg      120

uucggaccca aaaaccguag caucggcgcg gcagcgaaaa gccaggucau aagcaaugcg      180

aaaaacacag uccagggauu caaacgcuuc cacggccgag cauucuccga cccauucguc      240

gaagcagaga aaagcaaccu ggcauacgac aucguccagu uaccgaccgg ccuaaccggg      300

aucaaaguca ccuacaugga agaggaacgc aacuucacca cagaacaagu caccgccaug      360

cugcuaagca aacugaaaga gacugcagag uccguacuca agaaaccagu gguggacugu      420

gucguaagcg ugccgugcuu cuacacggac gccgaacgac guagcgugau ggacgcaaca      480

caaauagcgg gacugaacug ucuccgccua augaaugaaa cgacagcagu agcccucgcu      540

uacggaauau acaaacaaga ccuacccgcg cucgaagaga aaccccgcaa cgucgucuuc      600

guggacaugg gacacucggc cuaccaaguc uccgucugcg ccuucaaccg gggcaaacug      660

aaaguccucg ccaccgcauu cgacaccaca cuuggaggcc gaaaauucga cgaaguucuc      720

gucaaccacu ucugcgaaga guucgggaag aaauacaaac uugacauaaa auccaaaauc      780

cgagcacugc uccgacucag ucaagaaugc gaaaaacuaa agaagcucau guccgcgaac      840

gccagcgacc ucccccuauc caucgaaugc uuuaugaacg acgucgacgu cuccggaacc      900

augaaccgag ggaaauuccu agaaaugugc aacgacuuac uagcgagagu agaaccaccc      960

cuacgaagcg uacuagaaca gaccaaauua aagaaagaag auaucuacgc aguagaaaua     1020

gugggcggag caacccgcau acccgccgua aaagagaaaa ucucaaaauu cuuuggcaaa     1080

gaacucucga caacacuaaa cgccgacgaa gcagugaccc gcgggugcgc cuugcaaugc     1140

gcaauucuca gccccgcuuu caaaguaaga gaauuuucaa uaacagacgu cguaccauac     1200

cccauaucac uccgcuggaa cuccccagca gaagaaggaa gcuccgacug cgaagucuuc     1260

uccaaaaacc acgcagcccc cuucucuaaa guccucaccu ucuaccggaa agaacccuuc     1320

acccuagaag ccuacuacuc gucaccacag gaccuaccau aucccgaccc cgcaaucgcg     1380

caauucuccg uccaaaaagu aacaccccag agcgacggga gcagcagcaa aguuaaagua     1440

aaaguacgug uaaacguaca cggaaucuuc ucagucuccu cagccucccu cgucgaaguc     1500

cacaaaagcg aagaaaacga agaaccaaug gaaaccgacc agaaugcaaa agaagaagag     1560

aaaaugcaag ucgaccaaga agaaccccac gucgaggagc aacaacaaca aacuccagcc     1620

gaaaacaagg ccgaaucaga agaaauggag accucacaag ccgggucaaa agacaagaaa     1680

auggaucaac cgccccaagc gaagaaagcg aaagucaaaa cauccacagu cgaccucccc     1740

auagagaacc aacugcucug gcaaaucgac cgcgagaugc ucaaccucua caucgagaac     1800

gaaggaaaaa ugaucaugca ggacaaacua gaaaaagaaa ggaacgacgc caaaaacgcc     1860

guggaagagu acgucuauga aaugcgcgac aaauuaagcg gagaguacga gaaauuuguc     1920

uccgaagacg acagaaacuc cuucacacuu aaacucgaag acaccgaaaa cuggcuauac     1980

gaagacggcg aggaccagcc caaacaagua uacguggaca aacucgcaga gcugaaaaac     2040

cuaggacaac ccaucaaaau ccgauuucaa gaaagcgaag aacgccccaa gcuguucgag     2100

gaacucggaa aacaaaucca acaauacaug aaaaucauau cauccuucaa aaacaaagag     2160

gaccaauacg accaccucga cgccgcagau augacgaaag uagaaaaguc caccaacgaa     2220

gcgauggaau ggaugaacaa caaacucaac cuacaaaaca aacaaucgcu cacaauggau     2280

cccgugguaa agagcaagga gaucgaggca aaaauuaaag aacucacauc cacaugcagc     2340

cccauaaucu caaaacccaa accaaagguc gaaccgccaa aagaagaaca gaagaacgcc     2400

gagcaaaacg gcccaguaga cggccaaggc gacaacccag gcccccaagc agcggaacag     2460

ggaaccgaca cggccguccc cucagauucg gacaagaaac ucccagaaau ggacaucgac     2520

uaa                                                                   2523


<210>  944
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  944
augucagugg ucggcaucga ccuaggcuuc cucaacugcu acaucgccgu cgcccgcucc       60

ggcgggauug aaacaaucgc aaacgaguac ucggacaggu gcacacccgc uugcauauca      120

cugggaucgc ggacgcgcgc cauaggaaac gcagccaaaa gccagaucgu aacaaacgug      180

cgcaacacca uccauggcuu uaaaaagcuc cacggcagga gcuucgacga ccccaucguu      240

caaaccgagc gcaucagacu accauacgaa uuacagaaaa ugcccaacgg cagcgccggg      300

guaaaagucc gcuaccucga agaagaacga ccuuucgcga ucgaacaagu uaccggaaug      360

uuacuagcaa aacugaagga aaccucagag aacgcccuca agaaacccgu ggcagacugc      420

guaauaucaa ucccuagcuu cuucacagac gcagaaagac guucaguaau ggcggcagcc      480

caaguagcag ggcucaacug ccuccgacua augaacgaaa caacagccgu ggcccucgcc      540

uacggcauau acaaacaaga ccugccgcca cuagacgaaa agccccgcaa cgucguguuc      600

auagacaugg gacacagcgc cuaccaaguc cucgucugcg ccuuuaacaa gggcaaacuc      660

aaaguccucg ccacgacauu cgaccccuac cugggcggac gcaauuucga cgaagcucuc      720

guagacuacu ucugcgacga guucaaaaca aaauacaaaa ucaacgucaa ggaaaacuca      780

agagcccugc uccgacuaua ucaagaaugc gagaaacuaa agaaacucau guccgcgaac      840

gccagcgacc ucccacuaaa caucgaaugu uuuaugaacg accuggacgu cagcuccaaa      900

augaaccgcg cccaguucga acaacucugc gccagccuac uagcacgcgu ggagccaccc      960

cucaaagccg uaauggaaca agcgaaccuc cagcgcgagg acauaucaag caucgagaua     1020

guaggcggcg cgacgcgcau ccccgccgua aaagagcaaa ucacaaaauu cuuccucaaa     1080

gacauuucaa caacacuuaa ugcagacgaa gcaguagcca ggggaugcgc ucuacaaugc     1140

gccauccuca gcccggcauu caaaguacgc gaguucucca ucacagaccu aguccccuac     1200

ucaaucacac ucagauggaa aaccucauuc gaagacggga gcggagaaug cgaaguauuc     1260

ugcaaaaacc acccugcccc auucagcaaa gugauaacgu uccacaagaa agaacccuuc     1320

gaacuugaag cguucuacac aaaccuucac gaaguccccu acccugaugc gcgaaucggu     1380

ucauucacaa uacagaacgu auucccccaa agcgacggcg acucgagcaa aguaaaaguc     1440

aaaguccgcg uaaacaucca cggcaucuuc ucaguagcaa gugccagcgu gaucgaaaaa     1500

caaaaccucg aaggcgacca cagcgacgcc cccauggaga cagaaacauc guucaaaaac     1560

gaaaacaaag acaacaugga caaaaugcag guagaccaag aagaaggcca ccagaagugc     1620

cacgccgaac acacacccga agaagaaauc gaccacaccg gcgccaaaac aaaaucggca     1680

gucuccgaca aacaagaccg gcuaaaccaa acccucaaga aaggcaaagu aaaaucaauc     1740

gaccuaccca uacaguccuc acucugccgc caacugggcc aagaucuccu aaacucauac     1800

aucgaaaacg aaggaaaaau gauaaugcaa gacaaacucg aaaaagaacg gaacgacgcc     1860

aaaaacgcgg uagaggagua cgucuacgac uuucgggacc gacugggcac gguuuacgaa     1920

aaauucauca cacccgaaga ccuaagcaag cuaucugcgg uccuggaaga uaccgagaac     1980

uggcucuacg aagacggcga agaccaacca aaacaagugu acguagacaa gcugcaggaa     2040

cugaagaaau augggcaacc aauccaaaug aaauacaugg aacacgaaga aaggcccaaa     2100

gcacugaacg accuaggcaa gaaaauucaa uuagucauga aagugaucga agcguacaga     2160

aacaaagacg aaagauacga ccaccucgac ccuacagaga uggagaaagu agagaagugc     2220

auaucagacg ccauguccug gcuaaacagc aagaugaacg cccaaaacaa acucagccuu     2280

acgcaagacc ccguggucaa agucucagaa auaguugcga aaucaaagga gcuagauaac     2340

uucugcaacc ccauaauaua caaaccgaag cccaaagccg aaguccccga agacaagccc     2400

aaagccaaca gugaacauaa cgggccgaug gacggacagu caggcacuga gaccaaaagc     2460

gacucgacaa aagacagcag ucaacacaca aagucguccg gagagaugga agucgacuaa     2520


<210>  945
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  945
augaaacuca gccuagucgc agccaugcug cugcuccuca gcgcagcacg ggcagaagag       60

gaagacaaga aagaagacgu gggaacagua guaggcauag accucggaac gacauacagc      120

ugcguagggg uauucaaaaa cggacgaguc gagaucauag ccaacgacca gggcaacaga      180

auaaccccaa guuacguagc guucacaccc gagggugaac gacugaucgg agacgcagcg      240

aaaaaccaac ucacaagcaa ccccgaaaac acaguauucg acgcaaagcg acuaauaggc      300

cgcaccugga acgaccccuc gguccagcaa gacaucaaau uccugccauu caaagucguc      360

gagaagaaaa caaaacccua cauacaagua gacauagggg gcgggcagac gaaaacguuc      420

gcgccagaag aaauaagcgc aaugguacug acgaaaauga aagagaccgc agaagcguac      480

cugggcaaga aagucaccca cgcagucgua acagugccag ccuacuucaa ugacgcgcaa      540

cgacaagcaa caaaggacgc aggaacaauc gcgggacuga acgugaugcg aaucauaaau      600

gaacccaccg ccgccgcaau agcguacgga cuagacaaac gggaaggcga gaaaaacauc      660

cuagucuucg accugggcgg agguaccuuc gacguaaguc uccugacaau cgacaacggc      720

guauucgaag ucguagcaac aaacggggac acacaccugg gaggagaaga cuucgaccag      780

cgaguaaugg agcacuucau aaaacuauac aagaagaaaa ccggaaaaga cguaaggaaa      840

gacaacagag ccguacaaaa acucaggcgg gaggucgaaa aagccaaacg cgcccuaucc      900

agccaacacc aagcgcgcau cgaaauagaa ucauucuacg agggggaaga cuucagcgaa      960

acccuaacac gcgcaaaauu cgaagaacug aacauggacc uauuccgcag cacgaugaaa     1020

ccaguacaaa aaguccuaga ggacagcgac cuaaagaaaa gcgacauaga cgaaauagua     1080

uuagugggcg gcucgaccag gauaccaaaa auacaacaac ugguaaaaga guucuucaac     1140

ggcaaagaac caucgcgagg gaucaaccca gacgaagccg ucgcauacgg agccgcaguu     1200

caagcaggag uacugagcgg cgaccaagac acaggagacc ucguacuacu ggacgugugc     1260

ccacucaccc uaggcauaga aacaguaggc gggguaauga caaaacucau accaagaaac     1320

acggucgugc ccaccaagaa aagccagaua uucagcacgg caagcgacaa ccaacccacc     1380

guaacgauca aagucuauga aggagaacga ccccucacaa aagauaacca ccuacugggc     1440

accuucgauc uaacaggcau accaccagcc ccaagagggg uaccacaaau agaagugaca     1500

uuugaaaucg acguaaacgg gauucuccga gugaccgcgg aagacaaagg aaccggaaac     1560

aaaaacaaaa uaacgauaac caacgaccaa aacagacuca caccggaaga aaucgaaaga     1620

auggucaacg acgcagagaa auuugccgaa gaggacaaga aauugaaaga gcgaauagac     1680

accagaaacg aacucgaaag cuacgccuac ucacucaaaa accagauagg ugacaaagaa     1740

aaacuaggag ggaaacuaag cagugaagac aaagaaacca uggaaaaagc cgucgaagag     1800

aaaaucgaau ggcuagaauc acaccaagac gcagacauag aagacuucaa agccaaaaag     1860

aaagaacuag aagaaauagu acaaccaauc auauccaaac uauacggaag cgcagggccc     1920

ccacccacag gagaagagga cacagcggaa aaagacgaac uauaa                     1965


<210>  946
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  946
augcaagcac cccgggagcu cgcagucggc auugaucucg gaacaacaua cuccugcgua       60

ggaguguucc agcaagggcg cguggaaaua cucgcaaacg accaaggcaa ccggaccacc      120

ccaagcuacg uggccuucac cgacacagag cggcugguag gagacgcagc aaaaagccaa      180

gccgcgcuga auccccacaa cacagucuuc gacgcaaaaa ggcuaauugg aagaaaauuc      240

gcagacacaa caguacaaag cgacaugaaa cauuggcccu uccgagucgu cucagaaggg      300

ggcaaaccca aggucagagu cugcuacaga ggugaagaca aaacauucua ccccgaagag      360

auaucaagca uggugcucag caaaaugaaa gagacggccg aggcauaccu cgggcaaccg      420

gucaaacacg cgguaauaac agucccagca uacuucaacg auagccaacg ccaagccaca      480

aaagacgccg gagcaaucgc cgggcucaac guccuacgaa uaaucaacga accaacagcg      540

gcagcaaucg cuuacgggcu agacagaaga ggcgcaggcg aacggaacgu ccugauauuc      600

gaccuaggag gaggaacauu cgacguauca gugcuaagca ucgacgcagg aguauucgaa      660

gucaaagcca cggcaggaga cacacaccug ggcggggaag acuucgacaa caggcuagua      720

aaccacuuca uggaagaguu ccggcgcaaa cacgggaaag accuaucagg gaacaaaaga      780

gcccugcgaa ggcugagaac agccugcgaa cgcgcaaaaa ggacacuaag cagcuccaca      840

caagcaacac uagaaauaga cucccucuuc gaaggagucg acuucuauac cucgaucacg      900

cgcgcacgau ucgaagaacu augcagcgac cucuuccgau cgacccugga accgguagaa      960

aaagcccuaa gagacgcgaa gcuagacaag gcccaaauac acgacguagu ccucguagga     1020

ggaucgacac gcaucccaaa aguacaaaaa cuccuacaag acuucuucaa cgggaaagaa     1080

cucaacaagu caauaaaccc cgacgaagca guggccuacg gugccgcagu ucaggccgca     1140

guccugaugg gcgacaagug cgaaaagguu caagaccuac uacuccuaga cguggcaccc     1200

cucucccucg gacuagagac agcgggcgga gucaugacua cacuaaucca aagaaacgca     1260

accaucccaa caaagcaaac acaaacauuc acaaccuacu cagacaacca accaggcgua     1320

uucauccaag ucuacgaggg cgaacgcgca augaccaaag auaacaaccu acugggccga     1380

uucgagcucu caggcauacc cccagcaccc cgaggagucc cacaaauaga aguuacauuc     1440

gacaucgacg ccaacgggau auugagcgug accgcaacag accgcucaac cggaaaggca     1500

aacaaaauaa caauaacaaa cgauaaagga cgacuaagca aagaagaagu ggagcgcaug     1560

guacacgagg cggaacaaua caaggccgag gacgaagccc aacgggacag aguagccgcc     1620

aaaaacagcc uggaagcgca cgucuuccac gucaaaggau cacuacagga agaaucccuc     1680

cgagacaaaa uacccgagga agacagacga aaaaugcaag acaagugccg agaaguccua     1740

gccuggcucg aacacaacca acuggccgaa aaagaagaau acgaacacca aaagcgagaa     1800

cuagagcaaa uaugcagacc aauauucucg agacuauacg gcgggccggg cguaccuggc     1860

ggaucgagcu gcggcaccca agcccgacaa ggcgacccau caaccgggcc uauaaucgag     1920

gaaguggacu aa                                                         1932


<210>  947
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__P48741__HsHSPA7

<400>  947
augcaagcac cacgcgaacu cgcagucgga aucgaccuag gcaccacaua cucaugcguc       60

ggcguauucc aacaaggaag agucgaaauc cucgccaacg accaaggaaa ccgaaccacg      120

ccaagcuacg ucgcauucac agacacagaa cgccuggucg gcgacgcagc caaaagccaa      180

gccgcacuca acccacacaa cacaguauuc gacgcaaaac ggcucauagg ccgcaaauuc      240

gccgacacca ccguccaaag cgacaugaaa cauuggccau uccaagucgu aagcgaaggc      300

ggcaaaccca aaguccgagu cugcuacaga ggcgaggaca aaacauucua cccagaagaa      360

aucuccagca ugguacuaag uaaaaugaaa gaaaccgcag aagcauaccu aggccaaccc      420

guaaaacacg caguaauaac cguaccaacc uacuucucaa acagccaacg ccaagcaaca      480

aaagacgcag gagccaucgc cggccucaaa guccucccaa uaauaaacga agcaaccgca      540

gccgcaaucg ccuacggacu cgaccgacga ggcgccggca aacgaaacgu acucauauuc      600

gaccucggcg gcggcaccuu cgacguaagc guacuaagca ucgacgcagg agucuucgaa      660

gucaaagcaa cggccggcga cacacaccuu ggaggagaag acuucgacaa cagguuaguc      720

aaccacuuca uggaagaguu ccgccgcaaa cacggaaaag accucucagg aaacaaacgc      780

gcacugcgac ggcuacgaac agcgugcgaa cgcgcaaaac gcacccccuc cagcagcaca      840

caagccacuc ucgaaaucga cucacuguuc gaaggcgucg acuucuacaa auccauaaca      900

cgcgcacgcu ucgaagaacu cugcagcgac cucuuccgca gcacccucga acccguugaa      960

aaagcccuac gcgacgccaa acuagacaaa gcccaaaucc acgacuucgu ccugggcggc     1020

ggccuccacu cacaccccca aggagccgaa guagcagcag gacuccugca acgccaagga     1080

gcagaacaag aacaccaacc cuag                                            1104


<210>  948
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  948
augagcaaag gaccagcagu agggauagac cucggaacca cauacuccug cguaggggua       60

uuccagcacg gcaaaguaga aauaauagcg aacgaccaag gcaaccggac caccccuucc      120

uacguagccu ucaccgacac agagcgccuc aucggagacg cggccaaaaa ccaagucgca      180

augaacccca ccaacacagu auucgacgca aaaagacuca uaggcaggcg guucgacgac      240

gcagucguac aaagcgacau gaagcacugg cccuucaugg ucguaaacga cgcaggacgc      300

ccaaaagucc aaguagaaua caagggcgag acaaaauccu ucuacccaga agaggucucc      360

agcaugguac ugaccaaaau gaaagagaua gcagaagccu accucggaaa aacuguaacc      420

aacgcaguag ucacaguccc agccuacuuc aaugacagcc aacgccaggc caccaaagac      480

gccggaacca ucgccggacu uaacguacua cgcaucauca augagccaac ggcggccgca      540

aucgcguacg ggcucgacaa aaagguagga gccgaaagaa acguccugau cuucgaccua      600

ggaggaggaa cauucgacgu cucaauccuc acaauagaag acggcauauu cgaaguaaag      660

agcacggccg gcgacacaca ccugggagga gaagacuuug acaacagaau gguaaaccac      720

uucauagcag aguucaagcg caagcacaag aaggacauca gcgaaaacaa aagagcagua      780

cgccgccucc gcaccgccug ugaaagagca aaacgcaccc ucagcuccag cacccaagca      840

aguauagaaa uugacucacu auacgaaggc aucgacuucu acaccagcau cacccgagca      900

agauucgaag aauuaaacgc agaccucuuc agaggaaccc uggacccagu cgagaaagca      960

cuacgagacg caaaacuaga caaaagucaa auacacgaca uaguccuagu cggaggcagc     1020

acacgaaucc cgaagauaca gaaacuccuc caagacuucu ucaacggaaa agaacuaaac     1080

aaaagcauaa auccagacga agcagucgca uacggcgcag cgguccaagc ggccauacuu     1140

ucaggcgaca aaagcgagaa cguacaagac cugcugcucc uggacgucac gccgcucuca     1200

cuaggcaucg aaacagccgg cggcguaaug accgugcuca uaaaacgcaa cacaaccaua     1260

ccaacaaaac agacccagac cuucacgaca uacuccgaca accagccagg cguacucaua     1320

caggucuacg aaggagaacg cgcaaugaca aaagacaaca accuccuagg caaauucgaa     1380

cucacaggga uacccccagc accgcgcgga gucccacaaa uagaagucac cuucgacauc     1440

gacgcaaacg gaauccuaaa cguauccgcc guagacaaau caaccggaaa agaaaacaaa     1500

auaacgauca caaacgacaa aggccgccua agcaaggagg acaucgagag aaugguccag     1560

gaggccgaaa aauacaaagc cgaagacgaa aaacaacgcg acaaaguaag uagcaagaac     1620

agccuggaaa gcuacgcauu caacaugaag gcgacggucg aagacgaaaa acugcaggga     1680

aaaauaaacg acgaagacaa acagaaaauc cuagacaaau gcaacgaaau cauaaacugg     1740

cuggacaaaa aucaaaccgc cgaaaaagaa gaauuugaac accaacaaaa ggagcucgaa     1800

aaagugugca aucccauaau caccaaacua uaccaaucag cgggaggaau gcccggaggg     1860

augccgggcg gguucccagg agggggagca cccccaagcg gaggcgcaag cucgggcccc     1920

acgauagagg aggucgacua a                                               1941


<210>  949
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  949
augauaucag ccagccgcgc ggccgccgca agacuggugg gagcagccgc gagccgcgga       60

ccaacagcag cgcggcacca agacagcugg aacggacugu cacacgaagc auuccgacuc      120

gugaguagaa gagacuacgc gagcgaagcc auaaaagggg ccguagucgg aaucgaccuc      180

ggaacaacaa auaguugcgu agccgugaug gagggaaaac aagccaaagu acuagagaac      240

gcggagggag cgagaaccac accaagcguc guagccuuca ccgcagaugg agaaaggcuc      300

guaggcaugc ccgcaaaaag acaagcagug acgaacccaa acaacaccuu cuacgcgaca      360

aagcgccuca ucggccgacg cuacgacgac cccgaggugc aaaaagacau caaaaacgua      420

ccauucaaaa uagugagagc aagcaacggc gacgccuggg ucgaagccca cggcaaacua      480

uauagcccca gccagauagg ggccuucguc uugaugaaaa ugaaagagac cgcagaaaac      540

uaccuaggac acacagccaa gaacgcagua auaaccguac cugcauacuu caacgacagc      600

cagagacaag ccacaaagga cgccggccag auaagcggac uuaauguacu acgcguaaua      660

aacgaaccga cagccgccgc gcucgcauac ggccuagaca aaagcgagga caaaguaaua      720

gcaguauacg accuaggagg gggaacuuuc gacaucucga uacuagaaau acaaaaggga      780

guuuucgagg ucaagucaac aaacggggac accuucuuag gcggagaaga cuucgaccaa      840

gcgcugcuac gccacaucgu gaaagaguuc aaaagagaaa caggggucga ccucacgaaa      900

gacaacaugg cacuccaaag agucagagaa gcggcagaaa aagcgaaaug cgaacuaagc      960

agcagcgucc aaacagacau aaaccuaccc uaccuaacaa uggauagcuc aggcccaaaa     1020

caccugaaca ugaagcucac gcgcgcgcaa uucgagggga uagugacuga ccucaucaga     1080

agaaccauag caccaugcca aaaagcaaug caagaugccg aaguaagcaa aagcgacaua     1140

ggggaaguca uccuagucgg aggaaugacg aggaugccaa aaguacaaca aacaguacaa     1200

gaccucuucg ggagagcccc guccaaggcc guaaacccgg acgaggcagu agccauagga     1260

gcggccauac aaggaggagu ccuagccggg gacguaacag acgugcugcu gcucgacgua     1320

acaccccugu cucugggcau ugaaacccua ggaggcguuu ucacaaaacu caucaacaga     1380

aacacgacga uaccgacuaa gaaaucccaa gucuucucca cagccgccga cggucaaacc     1440

caaguagaaa ucaaagucug ccaaggagag agggaaaugg ccggggacaa caaauuacuc     1500

gggcaauuca cccucaucgg aaucccaccc gcgccccgag gcgugcccca gauagagguc     1560

acauucgaca ucgacgccaa cggaauagua cacguaagcg ccaaagacaa aggaacaggc     1620

cgggaacaac agauagucau acagucaagc ggaggccuca gcaaggacga caucgaaaac     1680

auggucaaaa acgcagagaa guacgcagaa gaggaccgga gaaagaaaga acgcguggaa     1740

gcaguaaaca uggccgaagg gauaauacac gacaccgaga caaaaaugga ggaguucaaa     1800

gaccagcugc ccgcggauga auguaauaaa cuaaaagaag aaauaagcaa aaugagggaa     1860

cuacucgcac gaaaggacuc ugaaacgggc gagaacauua gacaagcggc aagcagccuc     1920

caacaagcau cccugaagcu cuuugaaaug gcauacaaga aaauggcguc ggaaagggaa     1980

ggguccggga gcucaggcac gggagagcaa aaggaagacc aaaaggagga aaaacaauaa     2040


<210>  950
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  950
auggcggaca aagaagccgg aggaagcgac ggcccccgcg aaaccgcccc aacauccgcc       60

uacagcucgc ccgcccgcag ccuaggagac accggaauca caccccucuc ucccucccac      120

auugucaacg acaccgacuc caacguaucu gaacaacaau cauuccucgu aguagucgca      180

guagacuucg gcaccaccuc guccggauac gcauacucgu ucaccaaaga acccgaaugu      240

auccacguaa ugagacgcug ggaaggcggc gaccccgggg ucuccaacca gaaaacccca      300

accaccauac uacucacccc agaaagaaaa uuccacuccu ucggauacgc cgcccgcgac      360

uucuaccacg accucgaccc caacgaagcc aagcaauggc ucuacuugga aaaauucaaa      420

augaaacucc auacaaccgg agaccucacc auggacaccg accucacagc ugcaaacggc      480

aagaaaguca aagcacucga gaucuuugcc uacgcgcugc aauacuucaa agaacaagcc      540

cucaaagaac ucuccgacca agcaggguca gaguucgaaa auagcgacgu ccgauggguc      600

aucaccgucc cagcaauuug gaaacaaccc gcaaaacaau ucaugcgcca agccgccuac      660

caagcuggcc uagcuucacc agaaaacuca gaacaacuaa ucauagcacu cgaaccggaa      720

gcagcaagca ucuacugcag aaaacuacgc cuccaccaaa ugaucgaacu cagcucaaaa      780

gccgccguga acggcuacuc cggauccgac accguaggcg cgggcuucac acaagccaaa      840

gaacacaucc gucggaaccg ccaaucacga acauuccuag ucgaaaacgu cauaggcgaa      900

aucuggagcg aacuagaaga aggcgacaaa uacgucguag ucgacucagg cggaggcaca      960

guggaccuca ccguacauca aauccgccua ccagaaggcc accucaaaga acucuacaaa     1020

gcuacaggcg gaccauacgg aucacugggc gucgacuacg aguucgaaaa acuacuauac     1080

aagaucuucg gcgaagacuu uaucgaacaa uucaaaauca aaagacccgc cgccugggua     1140

gaccucauga ucgccuucga auccagaaag agggcagccg cgcccgaccg cacuaacccc     1200

cugaacauaa cacucccauu cagcuucauc gacuauuaca agaaauuccg cggccacuca     1260

guugaacacg cccuccgcaa auccaacgua gacuuuguaa aauggucauc ccaaggcaug     1320

cuccggaugu cccccgacgc caugaacgcc cuauucaaac caaccauaga uuccauaauc     1380

gaacaccuca gagaccucuu ccaaaaaccc gaagucucaa ccguaaaauu ccuuuuccua     1440

gucgggggau ucgccgaagc gcccuuacua caacaagcgg ugcaagcugc auucggcgau     1500

caaugccgaa uaauaauccc ccaagacgua ggccuaacca uacugaaagg ggcaguacuc     1560

uucggccucg accccgcagu aaucaaaguc cgacgcuccc cacuaaccua cggcguaggc     1620

guacucaaca gauacguaga aggaaaacau ccaccagaga aacuccuggu uaaagacgga     1680

accagauggu gcaccgacgu auucgacaaa uucaucagcg ccgaccaauc aguugcacuc     1740

ggcgaauuag uuaagcgaag cuacaccccc gcgaaaccau cccaacucgu caucgucaua     1800

aauaucuaca gcucagaaca cgacaacguc ucguucauca ccgaccccgg ggucaaaaag     1860

ugcggcacgc ucagacucga ccucaccggc accagcggga cggcaguacc agcgcgacgc     1920

gagauacaaa cccucaugca auucggcgac acagagauca aagccaccgc gauugacaua     1980

gcaacaucaa aaucugucaa agucggaauc gacuucuuaa acuacuaa                  2028


<210>  951
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  951
augcucgccg uccccgagau gggcuugcag ggccuauaca uaggcagcuc acccgaaaga       60

agcccagucc cauccccacc uggauccccc agaacccaag aauccugcgg aaucgcuccc      120

cucaccccau cacaaucccc aaaaccggaa guccgcgcac cccaacaggc cucauucuca      180

guuguugucg ccauagacuu cggcacaacc ucaagcggau acgccuucag cuucgccuca      240

gaccccgaag ccauacauau gaugcgcaaa ugggagggug gcgaccccgg cgucgcccac      300

cagaaaacgc ccacuugccu acuccucacc ccagaaggcg ccuuccacuc cuucggcuac      360

acggccagag acuacuacca cgaccucgac cccgaagaag caagggacug guuguacuuc      420

gaaaaauuua aaaugaaaau ucauagcgcc acagaccuaa cccuaaaaac gcaauuagaa      480

gcuguaaacg gcaaaaccau gcccgcccuc gaagucuucg cccacgcacu ccgcuucuuc      540

cgagaacacg cacuccaaga acuaagagag caaucaccca gccuccccga gaaagacaca      600

guacgcuggg uacugaccgu acccgccaua uggaagcaac cagcgaaaca auucaugaga      660

gaggccgcau accucgcagg gcuaguaucc cgggaaaacg cagaacaacu ccucauagca      720

uuagaaccag aagcagccuc agucuauugc agaaaacucc gccugcacca auugcucgac      780

cucagcggcc gcgccccagg aggcggucga cucggcgaac gacgaagcau agacucauca      840

uuccgccaag ccagagaaca gcuccgccga uccagacacu cacgaaccuu ccuuguagaa      900

uccggcgucg gagagcuuug ggccgaaaug caagccgggg accgauacgu cguagccgac      960

ugcggcggcg gaaccgucga ccuaacagua caccaacuag aacaaccaca ugguacccuc     1020

aaagaacucu acaaagccuc cggcgguccc uacggagccg uuggcguaga ccucgcauuc     1080

gaacaacuac ucugcagaau auucggagaa gacuuuauag cuaccuuuaa aagacaacga     1140

cccgcagccu gggucgaccu aacuauagcc uucgaagcac gcaaacgaac agccggccca     1200

cacagagccg gcgcacucaa cauaagccua ccauucucgu ucauagacuu cuaccgcaag     1260

caaagaggcc acaacgucga aaccgcccuc agacgaucau ccguaaacuu cguaaaaugg     1320

ucaagucaag gaaugcugcg aaugucaugc gaagcaauga acgagcuauu ccaaccgaca     1380

guaagcggaa ucauccaaca caucgaagcg cuccuagcgc gcccugaagu ccaaggcgua     1440

aaacuucuau ucuuaguugg aggauucgca gaaagcgccg uacuucaaca ugcaguccaa     1500

gcagcacucg gcgcacgcgg gcuccgaguc gucguccccc acgacguugg ccuaaccaua     1560

cucaaaggag ccguccucuu cggacaagcc ccaggggucg uccgagugcg cagaucaccg     1620

cuaacauacg gcguaggcgu gcucaaucgc uucguaccag gcagacaccc gcccgaaaaa     1680

cuccuagucc gagacggacg gcgcuggugc accgacgucu ucgaaagauu cgucgcggcu     1740

gaacaauccg uagcccucgg cgaagaggua cgucgcagcu acugcccagc ccgacccgga     1800

cagagacgag uucucaucaa ccucuacugc ugugcagcag aagacgcccg guucauaaca     1860

gaccccggcg uaagaaaaug cggagcacuc ucccuugaac uagaaccggc agacugcgga     1920

caagacaccg ccggcgcccc acccggaaga cgcgaaauca gagccgcaau gcaauucgga     1980

gacacagaaa ucaaagucac agcaguagac guaagcacca acagaagcgu cagagcaagc     2040

auagacuucc ucucaaacua g                                               2061


<210>  952
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  952
auggcccgcg aaaugaccau acuaggcucc gccguauuaa cccuccuccu ugcaggcuac       60

cuagcacaac aauaccuccc acuaccaacc ccaaaaguca uuggcauuga ccucggaacc      120

acguacugca gcgucggcgu cuucuucccu ggaaccggca aagucaaagu aauacccgac      180

gaaaacggcc acaucuccau accauccaug guuuccuuca ccgacaacga cguguacguc      240

ggauacgaau ccgucgaacu cgccgacagc aacccacaga acaccaucua ugacgcaaaa      300

cgauucaucg gaaaaauauu cacagccgaa gaacucgaag ccgaaaucgg acgcuaucca      360

uucaaaguac uaaacaaaaa cggcauggua gaguucuccg ucacaagcaa cgaaaccauc      420

accgucagcc ccgaguacgu aggaucuaga cugcuucuaa aacuaaaaga aauggccgaa      480

gccuaucugg gcaugcccgu cgccaacgca guaaucucgg uccccgcaga guucgaccua      540

aaacaacgaa acucaaccau agaagcggcc aaccuagccg gccucaaaau acuaagaguc      600

auaaacgaac ccacugccgc ggcuauggcc uacggucucc acaaagccga cgucuuccac      660

guccucguca ucgaccucgg cggcggaacc uuagacguca gccuacucaa caaacaaggc      720

ggcauguucc ucacccgcgc aaugagcggc aacaacaaac ucggaggcca agacuucaac      780

caacgccuac uccaauaccu cuacaaacag aucuaccaaa ccuacggcuu uguaccaucc      840

cgcaaagaag aaauacaccg acuccgacaa gccgucgaaa uggucaaacu caaccugacc      900

cuacaccaaa gcgcccagcu aucuguacua cuaaccgucg aagaacaaga ccgcaaagaa      960

ccccacucaa gcgacaccga acuccccaag gacaaacuca gcucugcgga cgaccaccgc     1020

gucaacuccg gcuucggccg aggcuuauca gacaagaaau ccggagaaag ccaaguccuc     1080

uucgaaaccg agauaucccg caaacuauuc gacacacuca acgaagaccu auuccagaaa     1140

aucuuaguac ccauacaaca aguccucaaa gaaggccacc uggagaaaac agaaauagac     1200

gaagucgucc uaguaggcgg cagcacacgc aucccccgca uuagacaagu cauccaagag     1260

uucuucggca aagaccccaa caccuccguc gaccccgacc uagccgucgu gaccggggua     1320

gcaauccaag ccggcaucga cggaggcucc uggccacuac aggucucggc acuugaaauc     1380

ccgaacaaac accuccagaa aaccaacuuc aauuaa                               1416


<210>  953
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  953
auggcagcaa ucggcgucca ccucggaugc acaucagccu gcgucgccgu cuacaaagac       60

gggcgcgccg gcgucgucgc aaacgacgcg ggcgaccgcg ucacaccagc cgucgucgca      120

uacuccgaaa acgaagaaau aguaggccua gccgccaagc aaucccgcau acgcaacauc      180

agcaacacag ucaugaaagu aaaacaaaua uuaggccgcu ccuccuccga cccacaggcc      240

caaaaauaca ucgcagaauc aaaaugccuc guaaucgaga aaaacggcaa acuacgcuac      300

gagaucgaca cuggcgaaga aaccaaguuc guaaacccag aagacgucgc ccgccuaauc      360

uucucaaaaa ugaaagaaac ggcccacuca guccucggcu ccgacgccaa cgaugucguc      420

auaaccguac cauucgacuu cggcgaaaaa caaaagaacg cacuaggcga agccgcccgc      480

gcagcgggau ucaacguccu acgccucaua cacgaaccau ccgcggcccu cuuagcuuac      540

ggaaucggac aagacucccc caccggcaag ucaaacaucc uaguauucaa acuaggagga      600

accucacuau cacucucagu cauggaggua aacucaggca ucuaccgcgu ccucagcacc      660

aacacagacg acaacaucgg aggagcccac uucaccgaaa cacucgccca guaccucgcc      720

uccgaguucc agcgaucguu caaacaugac guacgaggaa acgcacgcgc aaugaugaag      780

cucacgaaca gcgcagaagu cgcaaagcac ucccuaagca cacuaggcag cgcaaacugc      840

uuccuggacu cauuauacga aggacaggac uucgacugca acguaagccg cgccagauuc      900

gaacuccucu gcucaccccu cuucaacaaa ugcaucgaag ccauacgcgg acuacuagac      960

caaaacgggu ucaccgccga cgacaucaac aaagucguuc ucugcggcgg auccagccgc     1020

auccccaaac ugcaacaacu caucaaggac cuauuccccg ccgucgagcu gcuaaacucc     1080

auaccacccg acgaaguuau acccauugga gcagcaauag aggccggcau ccucaucggc     1140

aaagagaacc uccucgucga agacucccug augaucgagu gcuccgccag agacauacuc     1200

gucaaaggcg ucgacgaauc aggagcauca cgcuucacag uccuauuccc cucuggaaca     1260

ccccuuccag cacgacgaca acacacccua caagcaccag gcagcauuuc cuccgucugc     1320

cuagaacucu acgaauccga uggcaaaaac ucggccaaag aagaaaccaa guucgcacaa     1380

gucguacucc aagaccucga caagaaagaa aacggacucc gcgacauccu ggccgugcuc     1440

accaugaagc gagauggauc acuacacgug accugcaccg accaggaaac cggcaaaugc     1500

gaagccauca gcaucgaaau cgcauccuaa                                      1530


<210>  954
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  954
auguccgucg ucggacugga cgugggaagc caaagcugcu acauagcagu cgcccgggca       60

gggggcaucg aaacaaucgc caaugaguuc agcgacagau gcacuccaag cgucaucucc      120

uucggaucca aaaacagaac aauaggaguc gccgccaaaa accaacagau aacccacgca      180

aacaacaccg ucucaaacuu caaacgguuc cacggcagag cauucaacga ccccuucaua      240

caaaaagaaa aagaaaaccu aucauacgac cucgucccac ucaaaaacgg aggagucggu      300

aucaaaguca uguacauggg cgaagaacac cuuuucucag uagagcaaau aacagcaaug      360

cuacuaacca aacucaaaga gacagcagaa aacucgcuga agaaaccagu cacagauugc      420

gucauaagcg ucccgagcuu cuucaccgac gccgaacgac gcucaguacu agacgcagcc      480

caaaucgucg gccugaacug ucucagacua augaacgaua ugacggcagu cgcccuaaac      540

uacggcauau acaaacagga ccucccauca cuggaugaaa aaccacguau cguggucuuc      600

gucgacaugg gccacucagc auuccaaguc uccgcaugcg ccuucaacaa aggcaaacuc      660

aaaguacuag gcacagccuu cgacccauuc cuugggggca aaaacuucga cgaaaaacug      720

gucgagcacu uuugcgcaga guucaaaacc aaauacaaac ucgacgccaa aagcaaaauc      780

cgagcacuuc uacgauuaua ccaagaaugc gaaaaacuca agaaacucau gagcagcaac      840

ucgacagacc uccccuugaa caucgaaugc uucaugaaug acaaggacgu gucagggaag      900

augaaccggu cacaguucga agaacugugc gccgaacucc ugcagaaaau cgaaguccca      960

cuguacuccc uacucgaaca aacccaccug aaagucgaag acgucucagc aguagaaauc     1020

gugggagggg caacccgaau accugccguc aaagaacgua ucgcgaaauu cuucggaaaa     1080

gacaucagua caacgcucaa cgccgacgaa gcagucgcca gagggugcgc acuccaaugc     1140

gcgauccuau cccccgcguu caaaguacgc gaguucuccg ugacugacgc cgucccauuc     1200

ccaaucucac uaaucuggaa ccacgacuca gaagacacgg aaggagucca cgaagucuuc     1260

agccgcaacc acgcugcccc cuucucuaaa guauuaaccu uccuccgccg agguccauuc     1320

gaacucgaag cguucuacuc agacccacaa gggguacccu acccggaggc gaaaaucggc     1380

cgcuuuguag uacaaaacgu cucagcccag aaagacggcg aaaaaucccg ggucaaaguc     1440

aaaguccgcg ucaacaccca cggcauauuc accaucucaa cugccagcau ggucgagaaa     1500

guaccaacag aggagaacga aaugucaagc gaagccgaca uggaaugccu aaaucaaaga     1560

ccgccagaaa acccugacac cgacaaaaac guacaacaag acaauuccga agcagggacc     1620

cagccacaag uccagacaga cgcacaacag accagccaau cacccccauc cccagagcuc     1680

acgagcgaag aaaacaaaau accagacgca gacaaggcaa acgaaaagaa agucgaccag     1740

ccgccagaag cgaaaaagcc gaaaaucaaa guagucaacg ucgaacuccc cauagaagca     1800

aaccucguau ggcagcucgg gaaagaccuc cuaaacaugu acaucgagac agaaggcaaa     1860

augauaaugc aagacaaacu agaaaaagaa agaaacgacg cuaaaaacgc aguagaagag     1920

uacgucuacg aguuccgcga caaacucugu gggcccuacg aaaaauucau cugcgaacaa     1980

gaccaccaaa acuuccuaag acuccuaacc gaaacggaag acuggcucua cgaagaaggc     2040

gaggaccaag caaaacaagc cuacgucgau aaacucgagg agcuaaugaa aaucggcacg     2100

cccgucaaag uccgcuucca agaagcagaa gaacgaccga agauguucga agaacugggc     2160

cagcgcuugc aacacuacgc gaaaauagcg gccgacuucc gcaacaaaga cgaaaaauau     2220

aaccacauag acgaaucaga gaugaaaaag guagagaaaa gcguaaacga aguaauggaa     2280

uggaugaaca acgucaugaa cgcccaagcc aagaaaucac uagaccaaga ccccguuguc     2340

agagcccaag aaauaaaaac caaaauuaaa gaacucaaca acacaugcga gccagucguc     2400

acccaaccga aaccaaaaau agaaucucca aaacucgaaa gaaccccaaa cggcccuaac     2460

aucgauaaga aagaagagga ucucgaagac aaaaacaacu ucggggcaga acccccgcac     2520

caaaacggcg aaugcuaccc caacgagaaa aacucuguga acauggaccu agauuaa        2577


<210>  955
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  955
auggccgaca aaguccgacg acaacgaccg cgccgacgag uauguugggc gcucgucgcc       60

guacugcucg ccgaccuacu ggcccuaagu gacacccucg cagugaugag uguagaccua      120

ggcuccgaau ccaugaaggu cgcgauaguc aaaccaggag ugccgaugga aauaguccuc      180

aacaaggaau ccaggcgaaa aaccccagua auaguaaccc ucaaagaaaa cgagcgguuc      240

uuuggagacu cagcagcaag cauggcaauc aagaauccaa aagccacccu acgauacuuc      300

caacaccuac uaggaaagca ggcagacaac ccacacgucg cacuauacca ggccagguuc      360

ccggaacacg agcugaccuu cgacccccaa aggcaaacgg uacacuucca aaucagcagc      420

caacuacaau ucagcccaga agaaguccuc ggaauggucc uaaacuacag cagaagccuc      480

gcagaggauu ucgccgaaca gccaauaaaa gacgccguaa uaacaguccc aguauucuuc      540

aaccaagccg agcgacgagc cguccuacag gcagcacgca uggccgggcu caagguacuc      600

cagcuaauaa acgacaacac ggcaacggcc cuauccuacg gagucuuucg gagaaaagac      660

auaaacacaa ccgcacaaaa cauaauguuc uacgacaugg gcucaggcuc gacagucugc      720

acaauaguca cauaccagau ggucaaaaca aaggaagccg ggaugcaacc gcaacugcaa      780

auacgaggag ucggauucga ccgaacacug ggaggacuag aaauggaacu acgacuccga      840

gagaggcugg ccggccuauu caacgaacaa agaaaaggcc aacgcgcaaa agacguaagg      900

gaaaacccac gagcaauggc uaaacuacuc cgagaagcca accgacugaa aacaguacua      960

agcgcaaacg cagaccacau ggcgcaaauu gaagggcuaa uggacgacgu agacuucaaa     1020

gcaaaaguca cccgcgugga guucgaggaa cucugcgcag accuguuuga acgcgucccc     1080

ggccccguac aacaagcacu gcaaagcgca gaaaugagcc uagacgagau agaacaagua     1140

auccuaguag gcggcgccac acgaguaccc agaguucaag agguacuacu gaaagcuguc     1200

gggaaagagg aacuaggcaa aaacaucaac gccgacgagg ccgcagcaau gggagccgua     1260

uaucaagcag cagcauuaag uaaagcauuc aagguaaagc cguuuguagu acgggacgcc     1320

gucguauacc caauuuuagu cgaguucacg cgggaagucg aagaggaacc cggaauacac     1380

ucacugaaac acaacaaacg cguccuauuc ucacgaaugg gucccuaccc acaaagaaaa     1440

guaauaaccu ucaaccgaua cagccacgac uucaauuucc acaucaacua cggcgaccuu     1500

ggauuccuag ggcccgaaga ccugagaguc uucggaagcc agaaccucac cacagucaaa     1560

cugaaaggag ugggggacag cuucaagaaa uacccagacu augaaucaaa aggaauaaag     1620

gcacacuuca accucgauga aagcggagua cugagccugg acaggguaga aagcguuuuc     1680

gagacacugg uggaagacag ugccgaagaa gagagcacac uaacaaaacu gggcaacaca     1740

aucaguagcc ucuucggggg cggaacaacg ccagacgcaa aagaaaacgg gaccgacacc     1800

guacaagaag aagaagaaag cccagccgaa ggaagcaagg acgagccagg agagcaggua     1860

gagcucaaag aagaagcaga ggcgcccgua gaagacggcu cucagccacc uccgcccgaa     1920

cccaaaggag acgcaacacc agagggagag aaggcgaccg aaaaagaaaa cggcgacaaa     1980

agcgaggcgc aaaaaccguc ggagaaagcc gaggcgggac cagaaggagu agccccagca     2040

cccgaaggcg aaaagaaaca aaaaccagcg agaaaaagaa ggauggugga ggaaaucggc     2100

guggaacugg uagugcuaga uuuacccgac cucccagaag acaaacucgc gcagucggua     2160

cagaaauuac aagaccugac acuaagagau cuugaaaaac aagaacgaga gaaggcggca     2220

aacagucugg aagcguucau cuucgagacg caggacaaac uauaccagcc ggaguaccaa     2280

gagguaucaa ccgaagaaca aagagaggaa aucuccggca agcuaucggc ggccucaaca     2340

uggcucgagg augaaggggu aggcgccacc acagugaugc uaaaagaaaa gcuagcugaa     2400

cuaagaaaac uaugccaagg ucuauuuuuc cgagucgagg aaaggaagaa auggccagaa     2460

agacuaucgg cccucgacaa ccuacuaaac cacuccagca uguuucuaaa aggcgcgaga     2520

cuaauaccag agauggacca aaucuucacg gaagucgaaa ugaccacacu agaaaaagug     2580

auaaacgaga cgugggcaug gaaaaaugcc acacucgcag aacaagccaa acuacccgca     2640

acggaaaagc ccguccuacu cagcaaagac aucgaagcaa aaaugauggc guuagaccgc     2700

gaaguacagu accuacuaaa caaagcgaaa uucaccaaac cacgaccccg ccccaaagac     2760

aaaaacggca cacgggcaga gccaccacug aacgcaagcg ccucagacca aggggaaaag     2820

gucauacccc cggccggaca aaccgaagac gcggaaccaa uaagcgagcc cgaaaaggug     2880

gagacgggaa gcgaacccgg cgacacagag ccacuggaac uaggaggccc gggcgcagaa     2940

ccagagcaaa aggaacaaag cacagggcaa aagaggccac ucaaaaacga ugaacuauaa     3000


<210>  956
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  956
augccagaag aaacgcaaac gcaagaccaa ccaauggaag aggaggaagu agaaacguuc       60

gccuuccagg cagagaucgc ccaacuaaug agccugauaa uaaacacauu cuacucgaac      120

aaagagauau uccucagaga gcucauaagc aacagcucgg acgcacugga caaaauacga      180

uacgaauccc uaaccgaccc gagcaaacuc gacuccggca aagaacucca caucaaccua      240

auaccaaaua aacaggaccg gacacucacc aucgucgaca cagggauagg aaugacaaaa      300

gcggaccuga ucaacaaccu aggaacgauu gcaaaaagcg gaacaaaagc guucauggaa      360

gcccuccaag caggcgccga uauauccaug auaggacaau ucggcguggg guucuacuca      420

gcauacuuag ucgcggaaaa agucacggua auaacgaaac acaacgacga cgaacaguac      480

gcgugggaga gcuccgcagg cggcagcuuc acaguuagga cagacaccgg agagcccaug      540

gggcgaggga ccaaggucau ccuucaccuc aaagaagacc aaacggaaua ccucgaagaa      600

aggcgcauaa aggaaaucgu gaagaaacac ucccaauuca uaggauaccc uaucacacua      660

uucguagaaa aagaacgcga caaagaggua agcgacgacg aagcggaaga gaaggaagac      720

aaggaagagg aaaaagagaa ggaagagaaa gaaagcgaag acaagcccga aauagaagac      780

guaggcucgg acgaggaaga agaaaagaaa gacggcgaca aaaagaagaa aaagaaaaua      840

aaagaaaaau acauugacca ggaggaacuc aacaaaacga aaccgauaug gaccaggaac      900

ccggacgaca ucacaaacga agaauacggg gaguucuaca aaucgcucac aaacgacugg      960

gaagaccacc uagcggucaa acacuucagu guggagggac aacuagaguu cagagcacuc     1020

cuguucgucc caaggcgagc cccauucgac cuauucgaaa accgcaaaaa gaaaaacaac     1080

auaaaacucu acgucagaag agucuuuaua auggacaacu gcgaggaacu aauccccgaa     1140

uaccuaaauu ucauccgagg ggucguggac ucugaagacc ucccacuaaa caucucaaga     1200

gaaaugcugc agcaaaguaa gauccuaaaa gugauccgca aaaaccuagu aaagaaaugc     1260

cuggaacugu ucacggaacu ggcggaggau aaagaaaacu acaaaaaguu cuacgaacaa     1320

uucuccaaga acauuaaacu ggggauccac gaagacuccc aaaacagaaa gaaacugagc     1380

gaacuccugc gauacuacac cagcgcgucc ggagacgaga uggucagccu aaaggacuac     1440

ugcaccagaa ugaaagaaaa ccaaaaacac aucuacuaua uaacagggga aaccaaggac     1500

caagucgcaa acagcgccuu uguagagcgc cugagaaaac acggacucga agucauauac     1560

augauagaac caaucgacga auacugcgua cagcagcuga aggaguucga aggaaaaacg     1620

cuaguaucgg uaacgaaaga gggacuagag cuacccgaag acgaggaaga gaaaaagaaa     1680

caagaagaaa agaaaaccaa auucgagaac cucugcaaaa uaaugaaaga cauccuagaa     1740

aagaaaguag aaaaagucgu agugucaaac cgccucguca cgagcccaug uugcauaguc     1800

acgucaaccu acggauggac agccaacaug gagaggauaa ugaaagccca agcccuacga     1860

gacaacucaa caaugggaua cauggccgcc aagaaacacc uagaaauaaa ccccgaccau     1920

ucgauaauag agacucuccg acaaaaagcc gaggccgaca agaacgacaa gagcguaaaa     1980

gaccugguaa uccuccucua cgaaacggcc cuccuaucaa gcggguucag ccuagaagac     2040

ccacaaaccc acgccaaccg caucuacaga augauaaaac uaggacucgg aaucgacgaa     2100

gacgacccga ccgcggacga caccucagca gcgguaacag aggaaaugcc cccacuagaa     2160

ggggacgacg acacgagcag aauggaggaa guagacuaa                            2199


<210>  957
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  957
auggacuccu caaaacuaga cuccggcaaa ggacuccaca ucaaccucgu ccccaacaaa       60

caaaaccaaa cacucaccau aguagacaca cgcaucggca ugaccaaaac agaccucauc      120

aacaaccucg gcaccgucac caaauccgga acaaaagccu ucauggaagc acuccaagcc      180

gacgcagaca ucuccaugau cggacacuuc ggcgucggcu ucuacucagc auaccucguc      240

gccaaaaaag ucaccguaau cucaaaacac aacaacgacg aacaauacac cugggaaucc      300

uccgcaggcg gcuccuucac cguacgaaca gacgaauaa                             339


<210>  958
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  958
augcccgaag agguacacca uggugaagag gaagucgaga ccuucgccuu ccaagccgaa       60

auagcacaau uaaugagccu gauaaucaac accuucuacu cgaacaaaga aaucuuccug      120

cgcgaacuca ucucgaacgc aagcgacgcc cuagacaaga uaagauacga aucacugaca      180

gaccccagca agcuagacuc agggaaggag cucaaaaucg acaucauucc aaacccccaa      240

gaacggacac uaacccuggu ggacacaggg aucgggauga ccaaggccga ccugauaaac      300

aaccucggga caaucgccaa aagcggcacc aaagcguuua uggaggcccu acaagccgga      360

gccgacauca gcaugaucgg gcaauucggc gucggauucu acagcgccua ucuaguagcg      420

gaaaaaguag uagugaucac aaaacacaac gacgacgaac aauacgccug ggaaagcagu      480

gcaggaggca gcuucacggu gcgagccgau cacggagaac ccauaggacg gggcaccaag      540

gugauacugc accucaaaga agaccaaacc gaauaccugg aagaacgacg aguaaaggag      600

gucguaaaga agcacagcca auucauaggc uacccaauaa ccuuguaccu agagaaagaa      660

cgggaaaaag agauaaguga cgacgaagcu gaagaagaaa aaggcgaaaa agaagaagaa      720

gacaaagacg acgaagaaaa gcccaaaauc gaggacguag gcagcgacga agaagacgac      780

agcggaaaag acaagaaaaa gaaaacaaag aaaauaaaag agaaguacau cgaccaagaa      840

gaacucaaca aaacgaagcc cauauggaca agaaauccag acgauaucac gcaagaagaa      900

uacggagagu ucuauaagag ucuaaccaac gacugggaag accaccuagc ggucaaacac      960

uucagcgucg aaggacagcu agaguuccga gcccugcuau ucaucccccg aagggcaccc     1020

uucgaccuau uugaaaacaa aaagaagaaa aacaacauua aacucuacgu acgccgcguc     1080

uucauaaugg acagcugcga cgaacuaaua ccagaauacc ugaacuucau ccgcggaguc     1140

gucgacagcg aagaccuacc acugaacaua ucacgagaaa ugcugcaaca aagcaaaauc     1200

cucaaaguca uacgcaaaaa caucguaaag aaaugccuug aacuauuuuc ggaacuggca     1260

gaagacaaag aaaauuacaa gaaauucuac gaagccuuca gcaaaaaccu caaacuggga     1320

auccacgaag acuccacaaa ccgaagaaga cuaagcgaac uccuaagaua ccacaccagu     1380

caaagcggcg acgaaaugac aagccucuca gaauacgugu cccgaaugaa agaaacccag     1440

aaaagcaucu acuacaucac gggcgaaagc aaagaacaag uagcaaacag ugcuuucgua     1500

gaacggguga gaaagcgagg auucgaaguc guguauauga ccgaaccaau cgacgaauac     1560

ugcguacaac aacuaaaaga guucgauggc aagucccucg uaucagucac gaaagaaggc     1620

cuagaacugc cggaagacga agaagagaaa aagaaaaugg aagaaagcaa agcaaaauuc     1680

gaaaaccugu gcaaacucau gaaagaaaua cucgacaaga aagucgaaaa aguaacaaua     1740

agcaaccggc uagugagcag cccaugcugc aucgucacaa gcacauacgg cuggacggcg     1800

aacauggaaa gaauaaugaa agcacaagcc cuacgagaca acagcacgau gggauacaug     1860

auggcaaaga agcaccuaga aaucaaccca gaccacccaa ucguggaaac acuccgacaa     1920

aaagccgaag cagacaagaa cgacaaggcc guaaaagauc uagugguacu acuguucgaa     1980

accgcgcuac ucagcucagg auucagccuc gaggacccac aaacccacuc gaacaggauc     2040

uacagaauga ucaaacuagg ccugggaaua gacgaagacg aagucgccgc cgaagaaccc     2100

aacgcggcag ucccagacga aaucccacca uuggagggag acgaagacgc aagcaggaug     2160

gaggaaguag acuaa                                                      2175


<210>  959
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  959
augagggcgu uauggguccu agggcugugc ugcguccucc ugacguucgg cagcgucaga       60

gcagacgacg aaguggacgu agacggcacc guagaagaag accugggaaa auccagagag      120

gguagcagaa ccgacgauga agucgugcag cgagaggaag aagccaucca acucgacggg      180

cugaacgcgu cacagauacg ggaacuacga gagaaaagcg aaaaauucgc cuuccaagca      240

gaagucaacc gaaugaugaa guuaaucaua aacucacuau acaaaaauaa agaaauauuc      300

cucagagaac ugauaagcaa cgcgagugac gcacuagaca aaaucagacu caucagccuc      360

accgacgaaa acgcccuuag ugggaacgaa gaacuaacag ucaaaaucaa augcgacaag      420

gaaaagaacc uacuacacgu aacagacacg gguguaggaa ugacccggga ggaacucguc      480

aaaaaccucg gcaccauagc gaaaagcgga acaucagagu uccucaacaa aaugacagag      540

gcccaggaag acggacaaag caccagcgaa cugaucgggc aauucggagu aggauucuac      600

agcgcguucc ucguggcaga uaaggucauc gucaccucaa aacacaacaa cgacacccag      660

cacauauggg agagcgacag caacgaguuc uccguaaucg cggacccccg cgggaacacg      720

cucggccgcg gaaccacaau cacacucgua cucaaagaag aagcaagcga cuaccuagag      780

cucgauacaa uaaagaaccu ggugaaaaag uacagccagu ucaucaacuu cccaaucuac      840

guauggagca gcaaaacuga gacgguagaa gaaccaaugg aagaagagga agcagccaaa      900

gaagaaaaag aagagucgga cgacgaggca gcgguagaag aagaagaaga agagaagaaa      960

ccgaaaacca agaaaguaga gaaaacggua ugggauuggg aacuaaugaa cgacaucaaa     1020

cccauauggc agcgccccag caaagaaguc gaagaagacg aauacaaggc auucuacaag     1080

agcuucagca aagaaaguga cgacccgaug gccuacauac acuucaccgc agaaggggaa     1140

guaacauuca agagcauacu auucguccca accucagcgc cgcgaggacu cuucgacgag     1200

uacgggagca agaaaagcga cuacaucaaa cuguacguaa gacgcguauu cauaaccgac     1260

gacuuccacg acaugaugcc caaauaccua aacuuuguga aagggguagu agacagcgac     1320

gaccuacccc uaaacguguc cagagaaacc cuccagcagc acaaacuccu gaagguaaua     1380

aggaagaaac uggugcggaa aacacuagac augauaaaga aaauagccga cgacaaguac     1440

aacgacaccu ucuggaagga guucggcacc aacauaaaac uaggggugau cgaagaccau     1500

agcaaccgga cccgacucgc aaaacuccua agauuccaau caagccacca ccccaccgac     1560

auaacgagcc ucgaccagua cguggaaagg augaaggaaa agcaagauaa aaucuacuuu     1620

auggcgggcu ccucccgaaa agaagcagaa agcucacccu ucguagagcg acuacucaag     1680

aaaggguacg aaguuauaua ccugacagaa ccuguggacg aauacugcau acaagcacug     1740

ccggaguucg auggcaaacg cuuccaaaac guggcaaaag aaggcguaaa auucgacgaa     1800

agcgagaaaa cgaaagaauc acgcgaagca guagaaaaag aguucgaacc ccuacucaau     1860

uggaugaaag acaaagcauu aaaagacaaa auagaaaaag caguagugag ccaacgcuug     1920

accgaaagcc cgugugcccu cguagcaagc caguacggcu ggagcgggaa cauggagaga     1980

aucaugaaag cgcaggcgua ccaaacagga aaagacauau ccaccaacua cuacgcuuca     2040

caaaagaaaa ccuucgaaau aaacccaaga cauccgcuaa uccgcgacau gcugcgacga     2100

auaaaggagg acgaagacga caagacagua cucgaccucg cagucguccu cuucgaaacc     2160

gcaacgcuac ggucaggcua ccugcuccca gacacgaaag cauacggaga caggauagag     2220

aggaugcuca gacuaagccu aaacauagac ccggacgcca agguagaaga agaaccagag     2280

gaagaaccgg aagaaacggc agaagacacc acagaggaca cagagcaaga cgaggacgag     2340

gaaauggacg uaggaacuga ugaagaagaa gaaacggcca aagaaucgac agcagaaaag     2400

gacgaacuau aa                                                         2412


<210>  960
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  960
auggcacgag aacuaagggc ccuccuccuu uggggccgac gccuccgccc gcuacuucgc       60

gcgccagcac uggcagcugu cccaggaggc aaacccaucc uaugcccccg ccgaacaacc      120

gcacagcucg gucccagacg caacccagcu uggucccuuc aagcaggccg ccucuucucc      180

acucaaacag cagaagacaa agaagaacca cuccacagca uaaucucauc aaccgaauca      240

guacaaggcu caacaucuaa acacgaguuc caagccgaaa cuaagaaacu gcucgacaua      300

guggccagau cccuauacuc cgaaaaagaa gucuucaucc gcgaauugau cucaaacgca      360

uccgacgcac ucgaaaaacu acgacacaaa cucgucuccg acggccaagc ccucccagaa      420

auggaaaucc aucugcaaac uaacgccgaa aaaggcacca uaacaaucca ggacacaggc      480

aucggcauga cccaagagga acuugucucc aaccucggaa caaucgcccg cagcggaucc      540

aaagcauucc ucgacgcccu acaaaaccaa gcagaagcaa gcuccaaaau caucggacaa      600

uucggagucg gcuucuacuc agccuucaug gucgccgacc gcgucgaagu guacucacgc      660

ucagcugcac ccggaagucu aggcuaucaa uggcuaucag acggaagcgg ggucuucgaa      720

aucgcagaag ccucuggcgu gcgcacaggc accaaaauca ucauccaccu gaaauccgac      780

ugcaaagagu ucucgagcga agcacgaguc agggacguug uaaccaaaua cucaaacuuc      840

guauccuuuc cacuauaccu caauggccgu cgaaugaaca cccuccaagc aaucuggaug      900

auggacccua aagacguaag agaauggcaa cacgaagagu ucuaccgcua cguugcccaa      960

gcucacgaca aaccacguua cacccugcac uacaaaaccg acgcaccccu gaauauccga     1020

agcauuuucu acguccccga caugaaaccc ucuauguucg acguaucccg cgaacucggc     1080

uccucagucg cccuauacuc ccgcaaaguc cuuauacaaa ccaaagccac cgacauacuc     1140

ccaaaauggc uccgcuuuau acgaggaguc gucgacucag aagacauccc gcucaaccug     1200

agccgagaac uacuccaaga auccgcccuc auucgcaaac ugcgugacgu ccuccaacaa     1260

cgccucauca aauucuucau cgaccaauca aagaaagacg ccgaaaaaua cgcuaaauuc     1320

uucgaagacu acggccuauu caugcgcgaa ggaaucguga ccgccacaga acaagagguc     1380

aaagaagaca uagccaaacu ccuaagauac gaauccuccg cacugcccuc gggacaauua     1440

accucacuau ccgaauacgc aagccguaug cgcgccggga cccgcaacau cuacuaccuc     1500

ugcgccccca accgacaccu ggcagagcac uccccauacu acgaggcaau gaaaaagaaa     1560

gacaccgaag uccuuuucug cuucgaacaa uucgacgaac uaacccucuu acaccuaagg     1620

gaguucgaca aaaagaaacu caucucagug gaaacggaca ucguagucga ccacuacaaa     1680

gaagaaaaau ucgaagaccg cucaccagcc gcagaauguc uauccgaaaa agaaacagaa     1740

gaacucaugg ccuggaugcg caacguccua ggcagucgcg ucacaaacgu caaaguaacc     1800

cuuagacuug acacccaucc cgccauggua acaguccucg aaaugggagc cgcacgccac     1860

uuccuaagaa ugcagcaacu agccaaaaca caagaagaaa gagcccaacu ccuacaaccu     1920

acacuagaaa ucaacccccg ccacgcacuc aucaagaaac uaaaccaacu acgcgcaagc     1980

gaaccaggcc uagcgcaacu ccuaguagac caaaucuacg aaaacgccau gauagcagca     2040

ggccuaguag acgacccccg cgccaugguc ggccgccuca acgaacuccu aguaaaagcc     2100

cucgaaagac acuaa                                                      2115


<210>  961
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  961
augggcaaaa ucuccucacu ccccacacaa cuauucaaau gcugcuucug cgacuuccuc       60

aaagucaaaa ugcacacaau guccuccuca caccucuucu accuagcccu cugccuacuc      120

accuucacau caucagccac agccggcccu gaaaccuuau gcggagccga acucguagac      180

gcccuccaau ucgucugcgg agaccgaggc uucuacuuca acaaacccac cgguuacgga      240

ucaucauccc gccgcgcccc acaaacaggc aucgucgacg aaugcugcuu ccgcucaugc      300

gaccuccgaa gacuagaaau guacugcgca ccccucaaac ccgccaaauc cgcccgcucc      360

guccgagccc aacgccacac agacaugccc aaaacacaaa aagaagucca ccucaaaaac      420

gccucccgag gauccgccgg caacaaaaac uaccgcaugu aa                         462


<210>  962
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  962
augggcauac caaugggcaa auccaugcua guacuccuaa ccuuccuugc cuucgcaucc       60

ugcugcauag ccgccuaccg acccuccgaa acacucugcg gcggcgaauu agucgacacc      120

cuacaauucg ucugcggcga ccgcggcuuc uacuucuccc gaccagccuc ccgcgucucc      180

agacgcucac gcggcaucgu agaagaaugc ugcuuccgau caugcgaccu cgcccuccuc      240

gaaaccuacu gcgccacccc cgcaaaauca gaacgagacg ucucaacccc acccaccguc      300

cuccccgaca acuuccccag auaccccgua ggcaaauucu uccaauacga caccuggaaa      360

caauccaccc aaagacuuag acgcggccuc cccgcccuac uccgagcccg ccgcggacac      420

guacucgcca aagaacucga agccuuccgc gaagccaaac gccaccgccc acucaucgcc      480

cuacccacac aagaccccgc ccacggcggc gcacccccag aaauggccuc aaaccgaaaa      540

uaa                                                                    543


<210>  963
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  963
augaacuccu ucuccacauc agccuucggc cccgucgccu ucucccucgg acuccuccuu       60

guccucccag ccgccuuccc cgccccaguc ccccccggcg aagacucaaa agacguagcc      120

gccccccacc gacaaccccu uaccuccucc gaacgcaucg acaaacaaau acgauacauc      180

cuagacggca ucucagcccu ccgcaaagaa accugcaaca aauccaacau gugcgaaucu      240

uccaaagaag cccuagccga aaacaaccuc aaccucccca aaauggccga aaaagacggc      300

ugcuuccaau caggauucaa cgaagaaacc ugccuuguca aaaucaucac cggccuccuc      360

gaauucgaag ucuaccucga auaccuccaa aaccgcuucg aaucauccga agaacaagcc      420

cgcgccgucc aaaugucaac aaaaguccuc auacaauucc uccaaaaaaa agccaaaaac      480

cucgacgcca uaaccacccc cgaccccacc accaacgccu cacuacuaac caaacuccaa      540

gcccaaaacc aauggcuaca agacaugacc acccaccuca uccuccgcuc cuucaaagaa      600

uuccuacaaa gcucccuccg cgcccuacgc caaauguaa                             639


<210>  964
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  964
augccacuac uauggcuccg cggcuuccua cuggccucau gcuggaucau cguacgcagc       60

agccccacac caggaagcga gggacacagc gcagccccag acugcccaag cugcgcccua      120

gcggcccugc caaaagacgu acccaacagc caacccgaaa ugguagaagc cgucaaaaaa      180

cacauacuaa acaugcuaca ccuaaaaaaa aggccagacg uaacacaacc cgucccaaaa      240

gcagcacuac ucaacgcaau ccgcaaacuc cacgucggga aagucggaga aaacggauac      300

guagagauag aagacgacau cgggcgccgc gccgaaauga acgaacucau ggaacaaacc      360

ucagagauaa ucacguucgc cgaaagcgga acagcccgca aaacacuaca cuucgaaaua      420

agcaaagaag gcagcgaccu aagcgucguc gagcgcgcag aagucuggcu cuuccucaaa      480

guacccaaag caaaccgcac acgaacaaaa gucacaauac gacuguucca gcaacaaaag      540

cacccacaag gcucccucga cacaggcgaa gaagcagaag aaguaggccu aaaaggagaa      600

cggagcgaac uacuccuauc agaaaaaguc guagacgcac gcaaaagcac guggcacguc      660

uucccaguaa gcagcagcau acaacgacua cucgaccaag gcaaaagcag ccucgacguc      720

agaauagcau gcgaacaaug ccaagaauca ggcgccuccc ucguccuacu gggaaaaaaa      780

aagaaaaaag aagaagaagg cgaaggaaag aaaaaaggcg guggagaagg aggcgcagga      840

gcggacgagg aaaaagaaca aucccaccgc ccauuucuaa ugcugcaagc acggcaauca      900

gaagaccacc cccaccgccg ccgacgacga ggacuagaau gcgacggaaa agucaacauc      960

ugcugcaaaa aacaauucuu cgucagcuuc aaagacauag gauggaacga cuggauaaua     1020

gcgccaagcg gauaccacgc aaacuacugc gaaggcgaau gccccagcca cauagcaggc     1080

acaagcggga gcagccuguc guuccacagc accgugauca accacuacag aaugagagga     1140

cacuccccau ucgcaaaccu gaaaucgugc ugcgucccca ccaaacuacg accgaugagc     1200

augcucuacu acgacgacgg acagaacauc auaaaaaaag acauacaaaa uaugaucgug     1260

gaagagugcg gaugcagcua a                                               1281


<210>  965
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  965
auggacggcc ugccaggccg agcguuaggc gccgccugcc uccuacuccu agcagcaggc       60

uggcucggcc ccgaagccug gggaucacca accccaccac caacccccgc agccccuccc      120

ccacccccac cacccggcag ucccggcgga ucacaagaua ccugcaccuc augcggcgga      180

uuccgcagac cagaagaacu cggacgcgua gacggagacu uccucgaagc cguaaaaaga      240

cacauacuau cccgccucca aaugcgcggc cgacccaaca ucacacacgc cguccccaaa      300

gccgccaugg ucaccgcccu acgcaaacua cacgccggca aaguucgcga ggacggccga      360

gucgaaaucc cacaccucga cggccacgcc ucccccggcg cagacggaca agaacgaguu      420

agcgaaauca ucuccuuugc cgaaacagac ggccuagccu caucacgagu ccgacucuac      480

uuuuucaucu ccaacgaagg aaaccaaaac cucuucgucg uacaagcauc ccuauggcua      540

uaccuaaaac uccuacccua cgucuuagaa aaaggauccc gccgcaaagu ccgcgucaaa      600

gucuacuucc aagaacaggg ccacggcgac cgcuggaaca uggucgaaaa acgcguagac      660

cucaaacgcu ccggcuggca caccuucccc cuaaccgaag ccauccaagc ccucuucgaa      720

cgcggcgaac gacgccuaaa ccucgacgua cagugcgacu caugccaaga acucgccgua      780

guacccguau ucgucgaccc aggggaagaa agccacagac cauucgucgu cguccaagcc      840

agacucggcg acucccgaca ccgcauacgc aaacgaggcc ucgaaugcga cggccgcaca      900

aaccucuguu gccgccaaca auucuucauc gacuuccgcc uaaucgguug gaacgacugg      960

auuauagccc caacaggaua cuacggcaac uacugcgaag ggucaugccc cgccuaccua     1020

gccggagucc ccggcucugc cagcucauuc cacacagcag ucgugaacca auaccgcaug     1080

cgaggccuaa accccggcac cguaaacucu ugcugcaucc ccacaaaauu aucaaccaug     1140

uccaugcuuu acuucgacga cgaauacaac auagucaaac gcgacguccc caacaugaua     1200

guagaagaau gcggcugcgc cuaa                                            1224


<210>  966
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  966
auggcacuuc gcguccuccu ccuuaccgcc cuaacccuau gucauggauu caaccucgac       60

accgaaaaug ccaugaccuu ucaagaaaac gcccgcggau ucggccaguc uguaguacag      120

cuccaaggau cuagaguagu cgucggugcc ccucaagaaa ucguagcagc aaaccaacgc      180

gguagucuau accaauguga cuacucuacu ggcucgugcg aaccuaucag gcuccaaguc      240

cccguggaag ccgucaacau guccuuagga cuaucacugg ccgccaccac cuccccaccg      300

caacuccuag ccugcggacc caccguacac caaacaugua gcgaaaacac guacgucaaa      360

ggacucuguu uucucuucgg cagcaaccua cgccaacaac cccaaaaauu cccugaagcc      420

cucagaggcu gcccacaaga agacuccgac auagccuucc ucaucgacgg auccggcucc      480

auuauacccc acgacuuccg gaggaugaaa gaauuugucu cgacgguaau ggagcaacuc      540

aagaaaucaa aaacacuguu cagccuaaug caauacucgg aggaguuccg aauccacuuc      600

accuucaaag aguuccaaaa caaccccaac ccccguagcc uuguuaaacc cauaacccaa      660

cuacugggcc gaacacacac cgccaccggc auccgcaaag ucguccgcga acuauucaac      720

auaaccaacg gcgcacgcaa aaaugcuuuc aagauacuug uaguaaucac agacggagaa      780

aaauucggag acccauuggg auacgaagac gucauuccug aagccgaccg agaaggcgua      840

aucagauacg ugauaggugu aggcgacgca uucagaucag aaaaaucacg ccaagaacua      900

aacacaauag ccuccaagcc accccgagac caugucuucc agguaaacaa uuucgaggca      960

cuuaaaacua uucagaacca gcuccgugag aaaaucuucg ccaucgaagg aacucagaca     1020

ggauccuccu cgucuuucga acaugagaug agccaagaag gcuucagcgc ugccaucacc     1080

ucuaacggac ccuugcuauc uacagucggc uccuacgacu gggccggcgg cguguuccuc     1140

uacaccucca aagaaaaauc cacguucaua aacaugacac gagucgacuc ggacaugaau     1200

gacgcguacc uugguuaugc ugccgcaauu auacuuagaa accgugugca aucccuugua     1260

cucggcgcuc ccagauauca acacaucggc cucgucgcua uguuucguca aaauaccggg     1320

augugggaau ccaacgccaa ugucaaaggc acccaaaucg gcgccuacuu cggcgcgagc     1380

cuaugcucag ucgacgucga cucaaacgga uccaccgauc uaguccugau cggagcacca     1440

cacuauuacg aacaaaccag aggcggccag guaucagucu gcccacuccc ccgaggccgc     1500

gcccgcuggc aaugcgacgc cguccuuuac ggcgagcagg gccagccuug gggacgauuc     1560

ggagccgccc ucaccguacu cggugacguu aacggagaua aacuaacaga cgucgcaauc     1620

ggcgcccccg gagaagaaga caacagagga gcggucuacc ucuuucacgg aaccuccggg     1680

agcggaauca gcccguccca uucccagcgc auugcaggua gcaaacucag uccccgccuc     1740

caguacuucg gccaaucccu guccggcggc caagaccuua caauggacgg ccuaguagac     1800

cucaccgucg gugcucaggg ccauguccug cuucuacgcu cucaaccagu cuuacgagua     1860

aaagcaauaa uggaguucaa cccacgcgaa gucgcccgca acgucuucga augcaacgac     1920

caggucguaa aaggcaaaga agccggagaa guccguguau gccugcacgu acaaaagucc     1980

acccgcgacc gccuacggga aggccaaaua cagucugucg ucacuuauga ccucgcucuc     2040

gacuccggaa gaccgcacuc ucgggccguc uuuaacgaaa ccaaaaacuc aacacgacga     2100

caaacacagg ugcucggccu gacgcagaca ugcgagacgc ucaaauugca gcuaccaaac     2160

ugcaucgaag acccaguaag cccuauuguc cuucgccuaa acuucagccu cguggggaca     2220

ccacuaagcg ccuucggcaa ccuacgcccg guacucgcgg aagacgccca gcgccucuuc     2280

accgcccuuu uucccuucga gaaaaacugc ggcaacgaua acaucugcca agacgaucug     2340

ucgaucaccu ucagcuucau gucccucgac ugucucguag ucggaggccc ccgugaguuc     2400

aacguaaccg uaaccguccg caacgacgga gaagacagcu accgcacuca ggucaccuuu     2460

uucuuccccc ucgaccuguc uuacagaaaa guaucaacac uccaaaacca acgaucccaa     2520

cguucauggc gacuagccug cgaauccgcc agcuccacug aagucagcgg cgcccucaaa     2580

agcacguccu gcucgaucaa ccaccccaua uuccccgaga acucagaagu cacauucaac     2640

aucacauucg acguagauuc aaaggcuuca cucggaaaua aacugcuucu caaagccaac     2700

gucaccucag aaaauaauau gccccguacu aacaaaaccg aguuucaacu agaacucccg     2760

gucaaauacg ccgucuacau gguaguaacc ucucacggag uauccaccaa guaccucaac     2820

uucacugcau ccgaaaacac uucucgcguc augcagcacc aauaucaagu cuccaaccuc     2880

ggucaacguu cacugcccau cucccuagua uuccuggucc caguacgccu aaaccagacc     2940

gucauauggg acagacccca agucaccuuc ucagaaaacc uuagcucuac cugccauaca     3000

aaggaaagau uacccucaca cuccgacuuu cucgcagagc ucaggaaagc ccccguaguc     3060

aacugcucga uagcaguaug ccaacgaaua caaugcgaua ucccauucuu uggcauccag     3120

gaagaguuca acgccacccu gaaggguaac cucucauucg acugguacau aaagacauca     3180

cauaaccauc uacuuauagu cagcacagcc gaaauccugu ucaacgacuc aguguucacc     3240

cuccugcccg gccaaggagc cuucguacgc ucacaaaccg aaacaaaagu ugaaccuuuc     3300

gaaguuccca acccccuucc gcucauaguc ggcuccucag ucggaggccu ccuccuacuc     3360

gcccuaauaa ccgcagccuu guacaaacuc ggauucuuca aacgccagua caaagacaug     3420

augucagaag gagguccucc cggcgcagaa ccacaauag                            3459


<210>  967
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  967
auguucucac uaaaaacccu acccuuucuc cuacuccuuc acguccagau aucaaaagcc       60

uuccccgucu ccucuaaaga gaaaaacacc aaaaccgugc aagacuaccu cgaaaaauuc      120

uaccaacucc cguccaacca auaccaauca acacgcaaaa acggcacuaa cguaaucguc      180

gaaaaauuga aagaaaugca acgauucuuc ggccucaacg ucaccggcaa acccaacgaa      240

gaaacccucg acaugaugaa gaaaccccga ugcggaguac ccgacucugg cggcuucaug      300

cucacucccg gcaaucccaa augggaacgc acuaaccuca ccuaccgcau cagaaauuac      360

acaccccaac ucucagaagc cgaagucgaa agagcgauua aagacgcauu cgaacuaugg      420

uccgucgcca gcccccuaau cuucacccgc aucucccaag gugaagccga caucaacaua      480

gcauucuacc aacgcgacca cggugacaac uccccauucg acggcccaaa cggcauacuu      540

gcccacgcau uccaacccgg ucaaggaauc ggaggcgacg cccacuucga cgccgaagaa      600

accuggacca acacauccgc aaacuacaac cuauuccucg uugccgccca cgaguucggc      660

cacucccuag gcuuagcaca cuccuccgau ccaggugccc uaauguaucc aaacuacgcc      720

uuccgcgaaa ccuccaauua cucccuaccc caagaugaca ucgacggaau ccaagcaauc      780

uacggacucu cauccaaccc cauccaaccc accgguccau caaccccaaa acccugcgac      840

cccucccuca ccuucgacgc aaucaccacu cucagaggug aaauccucuu cuucaaagac      900

cguuacuucu ggcgaagaca cccacaacuc caacgcgucg aaaugaacuu uauuucacuc      960

uucuggcccu cgcuucccac cggcauccag gccgcauacg aagacuucga ccgcgaccua     1020

aucuuccucu ucaaagguaa ccaauacugg gcacuaucag gcuacgacau ccuucaaggc     1080

uaccccaaag acauauccaa cuacggcuuc ccauccuccg uccaggcaau cgacgcugca     1140

gucuucuaua gauccaaaac cuacuucuuc gucaacgacc aauucuggcg auacgacaac     1200

caacgacaau ucauggaacc cggcuacccc aaaucaaucu ccggcgcuuu ccccggcauc     1260

gaauccaaag ucgacgccgu uuuccaacaa gaacacuucu uccacgucuu cuccgggcca     1320

cgauacuacg ccuucgaccu caucgcccaa cgcgucaccc gaguagcacg cggcaacaaa     1380

uggcuuaacu gccguuacgg cuga                                            1404


<210>  968
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  968
augucccucu ggcaaccccu aguucuaguc cuccucguac uuggaugcug cuucgcagca       60

ccccgacaac gccaauccac ccuaguccuc uucccuggcg aucuucgaac aaaccugacc      120

gaccgccaac ucgcggaaga auaucucuac cgcuacggcu acacacgugu agccgaaaug      180

cgcggagaau ccaaaagccu agguccagca cuccuccucc uccaaaaaca acuuucacuc      240

cccgaaacgg gcgaacucga cuccgccacc cucaaagcaa ugagaacacc acgcugcggg      300

guacccgacu uagggagauu ccaaacguuc gaaggagacc uaaaguggca ccaccacaac      360

auaacuuacu ggauacaaaa cuacagcgag gaccugcccc gagcagucau cgacgacgcc      420

uucgcaagag ccuucgcccu auggagcgcc guaacacccc ucaccuucac ccguguauac      480

ucccgagacg ccgacauugu cauccaauuc ggcguagccg aacacggaga cggcuaccca      540

uucgacggca aagacggccu auuggcacac gcauuuccac ccggcccagg aauacaaggc      600

gacgcccacu uugacgauga cgaacucugg agccugggaa aaggagucgu aguccccacc      660

agauucggca acgcagacgg agcagcaugc cacuuccccu uuauauucga aggccgcucu      720

uacagcgccu gcacuaccga uggccgcucc gauggucuac ccuggugcuc caccaccgcc      780

aacuacgaca ccgaugaucg cuucgguuuc uguccaucug aaagacucua cacccaggac      840

ggcaacgccg acggcaaacc cugccaauuu ccauucaucu uccaaggcca aucuuacucc      900

gcaugcacca cagacggccg auccgaugga uaucgcuggu gcgccacaac ugccaauuac      960

gaccgagaca aacucuucgg auucugccca acccgagcag acucaaccgu aaugggagga     1020

aacucagccg gcgaauuaug cguauuuccc uucaccuucc ucggaaaaga guacuccacg     1080

ugcaccagcg aaggccgagg agacggacga cuauggugcg ccaccacauc aaacuucgac     1140

uccgacaaga aauggggcuu cugccccgau caaggcuacu cucuguucuu agucgccgca     1200

cacgaguucg gacacgcccu gggacuagac cacaguucag uccccgaagc gcucauguac     1260

cccauguacc gcuucacaga aggaccacca cuacacaagg acgacguaaa cggcaucaga     1320

caccuauaug guccccgacc agaacccgaa ccacgcccuc ccacuaccac uaccccacaa     1380

ccaacugccc cacccacagu auguccaaca ggaccaccca ccguacaccc cuccgaacgc     1440

cccaccgccg gcccuaccgg accucccucc gcagguccca caggaccacc cacagccggc     1500

cccuccaccg ccaccacagu ucccuuaucc ccugucgacg acgcaugcaa cgucaacaua     1560

uucgacgcua ucgccgaaau cggcaaucaa cuauaccugu ucaaggacgg caaauauugg     1620

cgcuucucag aaggccgagg cagccgcccu caagguccau uccucauugc cgacaaaugg     1680

cccgcccucc ccagaaaacu ugacuccguc uucgaagaac gucucuccaa gaaauuauuc     1740

uucuucucag gccgucaagu cugggucuac accggcgcca gcguccucgg ccccagacgu     1800

cuagacaaac uuggacucgg agccgacguc gcucagguaa ccggggcucu gcgauccgga     1860

cgcgggaaga uguugcuauu cagcggacgc agacuauggc gcuucgacgu caaagcccaa     1920

auggucgacc cgagauccgc cuccgaaguu gaccguaugu ucccaggcgu gccccucgac     1980

acccacgacg uauuccaaua ccgcgaaaaa gcauacuucu gccaggaccg cuuuuauugg     2040

cgagucucuu cccgaucuga acuuaaccaa gucgaccaag uaggauaugu caccuacgac     2100

auccuccagu gccccgagga cuaa                                            2124


<210>  969
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  969
augcacccag gcguccucgc agcuuuccuc uuccucuccu ggacacacug ccgcgcauua       60

ccccuccccu caggaggcga cgaagacgac cucuccgaag aggaccucca auucgccgaa      120

cguuaccucc gcuccuacua ccacccgaca aaccucgcag gaauacucaa ggaaaacgcc      180

gccuccucca ugaccgaacg ccuuagagaa augcagucau ucuucggccu agaaguaacc      240

ggaaaacuag acgacaacac ccuagacguc augaaaaaac cccgaugcgg uguccccgac      300

gucggcgaau acaacgucuu cccccgcacc cuuaaguggu ccaaaaugaa ccugaccuau      360

cgcauaguca acuacacgcc agacaugacc cauuccgaag ucgaaaaagc auucaaaaaa      420

gcguucaaag uaugguccga cgucacccca cuuaacuuca cacgccucca cgacggaauc      480

gcagacauca ugauaagcuu cgguaucaaa gaacacggcg acuucuaccc cuucgacggc      540

ccaucaggcc uacuagccca cgcauucccc cccggcccga auuacggcgg cgacgcccac      600

uuugacgaug acgaaaccug gacauccucc uccaaagguu acaaccuauu ccuaguagcc      660

gcacacgaau ucggccacuc ccucgggcua gaccacucca aagaccccgg agcccucaug      720

uuccccauau acacuuacac cggcaaaucc cacuucaugc uacccgacga cgacguacaa      780

ggcauccaau cccuguacgg cccaggcgac gaagacccaa accccaaaca ccccaaaacu      840

cccgacaaau gcgaccccuc ccucucccua gacgccauca ccucacuccg cggcgaaaca      900

augauauuca aagaccguuu cuucuggcgc cuccacccac aacaaguaga ugcagaacuc      960

uuccuaacaa aauccuucug gcccgaacua ccaaaccgaa ucgacgcugc auaugaacau     1020

ccaucccacg accucauuuu cauauuucga ggccgaaaau ucugggcacu aaacgguuac     1080

gacauccucg aaggcuaccc caaaaaaauc uccgaacuag gccuucccaa agaaguaaaa     1140

aaaaucucag ccgccgucca cuuugaagac accggaaaga cucuacuauu cucaggcaac     1200

caagucuggc gauacgacga caccaaccac auaauggaca aagacuaccc caggcuaaua     1260

gaagaagacu uuccaggcau cggagacaaa guagacgccg uauacgagaa aaacggcuac     1320

aucuacuucu ucaacggccc cauacaauuc gaguacucca ucugguccaa ucgaaucgua     1380

cgcgucaugc ccgccaacuc aauccucugg ugcuaa                               1416


<210>  970
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  970
auggagaccc ccaacaccac agaagacuac gacaccacca ccgaauucga cuacggugac       60

gccacccccu gucaaaaagu caaugaacgc gccuucggcg cacaacuacu accgccccuc      120

uacucgcucg uuuucguaau cggccucguc ggaaauauac ucgucguccu cguccuaguc      180

caauacaaac gccucaaaaa caugacuuca aucuaccucc uuaaccuagc caucucugac      240

cuccucuucc uauucacacu cccauuuugg aucgauuaca aacucaaaga cgacuggguc      300

uucggcgacg caaugugcaa aauccuauca ggcuucuacu acaccggccu auauagcgaa      360

aucuucuuca uuauccuucu caccaucgac cgcuaccucg ccauagucca cgcagucuuc      420

gccuugcgcg cacgcaccgu aacuuuugga gucauaaccu ccaucaucau uugggcucuc      480

gccauccucg ccucaaugcc cggccuauac uucuccaaaa cacaauggga auucacccac      540

cauacuugcu cccuccacuu cccacacgag ucccuaagag aauggaaacu cuuucaagca      600

cucaaauuaa accucuuugg ucucguucuu ccccuccucg ucaugauaau uugcuacacc      660

ggcaucauca aaauccuccu ccgccgucca aacgaaaaaa aauccaaagc cguccgccua      720

aucuucguaa uaaugaucau cuucuuccuc uucuggaccc ccuacaaccu cacaauccuc      780

aucuccgucu uccaagauuu ccucuucacc cacgaaugcg aacaaucucg ucaccucgac      840

cucgcugucc aagucacaga agucaucgcu uacacacacu gcugcgucaa ccccguaauc      900

uacgcauucg ucggugaacg auuccgcaaa uaccuccgcc aacucuucca ccgccgcgua      960

gccguccacc ucgucaaaug gcuucccuuc cucuccgucg accgacucga acgcguaucu     1020

agcaccuccc cuuccacagg agaacacgaa cucuccgccg gcuucuaa                  1068


<210>  971
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  971
augcgcaccc ucgccugccu ccuccuccuc ggcugcggcu accucgccca cguccucgcc       60

gaagaagccg agaucccacg cgaaguaauc gaacgccucg cccgcuccca aauacacucc      120

auccgcgacc uccaacgccu ccucgaaauc gacucaguag gcuccgagga cucacucgac      180

accucacucc gcgcccacgg cguccacgcc accaaacacg uccccgaaaa aagaccacuc      240

ccaauccgac gaaaacgauc caucgaagaa gccguccccg cagucugcaa aacccgcacc      300

gucauauacg aaaucccacg aucccaaguc gaccccaccu ccgccaacuu ccuaaucugg      360

cccccaugcg ucgaagucaa acgaugcacc ggcugcugca acacauccuc cguaaaaugc      420

caacccagcc gcguccacca ccgcuccgua aaaguagcaa aagucgaaua cguacgcaaa      480

aaacccaaac uaaaagaagu ccaaguccgc cucgaagaac accuagaaug cgcaugcgca      540

acaacauccc uaaaccccga cuaccgcgaa gaagacaccg gccgaccacg agaauccggc      600

aaaaaacgca aacgcaaacg ccucaaacca acauaa                                636


<210>  972
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  972
augaaccgau gcugggcacu cuuccuaucc cucugcugcu accuacgccu agucucagcc       60

gaaggcgacc ccauccccga agaacucuac gaaaugcuca gcgaccacuc cauccgaagc      120

uucgacgacc uucaacgccu acuccacggc gaccccggcg aagaagacgg agccgaacuc      180

gaccuaaaca ugacccgcuc ccacuccggc ggagaacucg aaucacucgc acgcggacgc      240

agaucccucg gcucccucac caucgccgaa ccagccauga uagcagaaug caaaacccga      300

acagaagucu ucgaaaucuc acgccgccuc auagaccgaa ccaacgccaa cuuccucguc      360

uggcccccau gcgucgaagu ccaaagaugc uccggcugcu gcaacaaccg caacguccaa      420

ugccgcccaa cccaagucca acuccgccca guccaaguac gcaaaaucga aaucguacgc      480

aaaaaaccaa ucuucaaaaa agccaccguc acccuagaag accaccucgc cugcaaaugc      540

gaaaccguag ccgcagcccg acccguaaca cgcucucccg gcggcagcca agaacaacga      600

gcaaaaacac cccaaacacg cgucacaauc aggaccgucc gcguccgcag acccccaaaa      660

ggcaaacacc gcaaauucaa acacacccac gacaaaaccg cacucaaaga aacccuaggc      720

gcauaa                                                                 726


<210>  973
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  973
augucccucu ucggccuccu ccuccucacc ucagcccuag caggccaacg ccaaggcacc       60

caagccgaau ccaaccucuc cuccaaauuc caauucucau ccaacaaaga acaaaacggc      120

guacaagacc cgcaacauga acgcauaauc accguaucca ccaacggcag cauccacucc      180

ccaagguucc cccauaccua cccccgcaac accguccuag ucuggcgccu ugucgccguc      240

gaagaaaacg ucuggaucca acugacauuc gacgaacgcu ucggccucga agaccccgaa      300

gacgacaucu gcaaauacga uuucgucgaa guagaagaac cuuccgaugg caccauccuc      360

ggccgcuggu gcggaagcgg caccgucccc ggcaaacaaa ucucaaaagg caaccaaaua      420

cgcauccgau ucgucuccga cgaauacuuc ccaucagaac ccggauucug cauacacuac      480

aacaucguca ugccacaauu caccgaagcc gucucacccu ccguccuacc ccccucagcc      540

cucccccucg accuacucaa caacgccaua acagccuuuu ccacccucga agaccucauc      600

cgauaccucg aaccagaacg auggcagcuc gaccuagaag accucuaccg ccccaccugg      660

caacucuuag gcaaagccuu cgucuucggc cgcaaaucgc gcguaguuga ccuuaaccuc      720

cuaaccgaag aaguacgccu cuacagcugc accccacgca acuucuccgu aucaauccgc      780

gaagaacuca aacguaccga caccauauuc uggcccggau gccuccuagu caaaagaugc      840

ggcggaaacu gcgccugcug ccuccauaac ugcaacgaau gccaaugcgu acccuccaaa      900

guaaccaaaa aauaccacga aguccuucaa cuccgcccaa aaacaggcgu acguggccuc      960

cauaaaucac uuaccgacgu cgcccucgaa caccacgaag aaugugacug cgucugucgc     1020

ggauccaccg gaggauaa                                                   1038


<210>  974
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  974
augcaccgcc ucaucuucgu cuacacccua aucugcgcca auuucugcuc augccgcgac       60

accucugcca caccgcaaag cgcuucaauc aaagcacucc ggaacgccaa ccugcgacga      120

gacgaccucu accgccgcga cgaaaccauc caagucaaag gaaacggcua cguacaaagc      180

ccccgauucc caaacuccua cccccgcaac cuccuacuca ccuggagacu acacucccaa      240

gaaaacaccc gaauacaacu cguauucgac aaccaauucg gacuagaaga agcugaaaac      300

gacaucugcc gauacgacuu cguagaaguc gaagacauaa gcgaaacauc cacaaucauc      360

agaggccgcu ggugcggcca caaagaagua ccaccccgca ucaaaucccg cacaaaccaa      420

aucaagauaa ccuucaaauc agacgacuac uucgucgcca aacccggauu caaaaucuac      480

uacucccucc uagaagacuu ccaacccgcc gccgccuccg aaacaaacug ggaaucaguc      540

accucaagca ucucaggugu aucauacaac ucccccuccg ucaccgaccc cacacucaua      600

gcagacgccc ucgacaagaa aauagcugaa uuugacaccg ucgaagaccu ccucaaauac      660

uucaaccccg aauccuggca agaagaccuc gaaaacaugu accuggauac accacgcuac      720

agaggccgau cauaccacga ccgaaaaagu aaagucgacc uugaccgccu caacgacgac      780

gccaaacgcu auagcugcac cccucgaaac uacuccguca acauccgaga agaacuaaaa      840

cucgcaaacg ucguauucuu cccacguugc cuccuugucc agcgaugcgg aggcaacugc      900

ggcugcggca ccgucaacug gcggagcugc acaugcaacu ccggcaaaac cguaaagaaa      960

uaccacgaag uacuccaauu cgaaccaggu cacaucaaac gucgcggcag agcuaaaacc     1020

auggcauuag ucgacauaca acuagaccac cacgaacgau gcgacugcau cugcagcuca     1080

cgacccccac gcuaa                                                      1095


<210>  975
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  975
auggucacac acuccaaauu ccccgccgcc ggcauguccc gacccuuaga caccuccuua       60

cgccuaaaaa ccuucuccuc caaauccgaa uaccaacucg uagucaacgc aguacgcaaa      120

cuccaagaau ccggauucua cuggucagcc guaaccggcg gcgaagccaa ccuccuccua      180

uccgccgaac cagccggcac cuuccuaauu cgcgacucau ccgaccaacg ccacuucuuc      240

acccucuccg ucaaaaccca auccggcaca aaaaaccucc gcauccaaug cgaaggcgga      300

ucauucuccu uacaauccga cccccgcucc acccaaccag ucccccgauu cgacugcgua      360

cucaaacucg uccaccacua caugccaccc cccggcgccc ccuccuuccc uucacccccc      420

accgaacccu ccuccgaagu cccugaacaa cccucagccc aacccuuacc cggcuccccc      480

ccacgccgcg cauacuacau cuacucaggc ggcgaaaaaa ucccacucgu ccucucccgc      540

ccccucuccu ccaauguagc cacacuccaa caccucugcc gcaaaaccgu caacggccac      600

cuagacuccu acgaaaaagu aacccaacuc cccggaccca uacgcgaauu ccuagaccaa      660

uacgacgccc cacuauaa                                                    678


<210>  976
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  976
augguccccu ccgccggcca acucgcccuc uucgcccucg gcauaguacu cgcagccugc       60

caagcccuag aaaacucuac cuccccccuc uccgccgacc ccccaguagc agccgccguc      120

gucucacacu ucaaugacug cccagacucc cacacccaau ucugcuucca cggcaccugc      180

cgcuuccucg uacaagaaga caaacccgcc ugcguaugcc auuccggaua ugucggcgcc      240

cgcugcgaac acgccgaccu ccuagcagua gucgcagcau cacaaaaaaa acaagcaauc      300

acagcacuug ucgucgucuc aaucgucgcc cucgccguac uaaucaucac cugcguccuc      360

auccacugcu gccaaguccg aaaacacugc gaauggugcc gagcacucau cugccgccac      420

gaaaaacccu cagcccuacu caaaggccga accgcaugcu gccacuccga aacagucguc      480

uaa                                                                    483


<210>  977
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  977
augccuccau ccggccuacg acuacucccc uuacuccuac cccuccuaug gcuccuaguc       60

cuaacacccg gccgccccgc agccggccua ucgaccugca aaaccaucga cauggaacuc      120

gucaaacgca aacgcaucga agccauucga ggacaaaucc uauccaaacu cagacucgcc      180

ucaccucccu cccagggcga aguaccaccc ggcccccuuc ccgaagcagu ccucgcccuc      240

uacaacucaa caagagaccg cgucgccggc gaauccgccg aacccgaacc cgaacccgaa      300

gccgacuacu acgccaaaga aguuacccga gugcuaaugg ucgaaaccca caacgaaauc      360

uacgacaaau ucaagcaguc aacacacuca auauacaugu ucuuuaauac cucagaacuc      420

cgcgaagcag uaccugaacc cguccuccua ucccgcgccg aacuccgacu ucucagacuc      480

aaacuuaagg ucgaacaaca cgucgaacuc uaccaaaaau acuccaauaa uucauggcgc      540

uaccucucca aucgacuccu ugcccccucc gacucacccg aauggcucuc cuucgacguc      600

accggagucg uacgccagug gcucucccgc ggcggcgaaa ucgaaggcuu ccgccucucc      660

gcacacugcu ccugugacuc ccgcgacaau acccuacaag ucgacaucaa cggcuucacc      720

accggccgac gcggcgaucu cgccaccauc cacggcauga accgcccauu ccuccuccua      780

auggccacac cccucgaacg ugcccaacau cugcaaucau cccgccaccg acgugcccuc      840

gacaccaacu acugcuucuc cucaaccgag aaaaauugcu gcguacgaca acuauacauc      900

gacuuccgca aagaccucgg auggaagugg auccacgaac ccaaaggaua ccacgccaac      960

uucugccucg gccccugccc cuacaucugg ucccucgaca cacaauacuc caaaguucuc     1020

gcccucuaca accaacacaa ucccggcgca ucagcagccc ccugcugcgu cccccaagcc     1080

cuagaacccc ucccaaucgu cuacuacguc ggccgaaaac caaaagucga acaauuaucc     1140

aacaugaucg uccgcagcug caaaugcucc uga                                  1173


<210>  978
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  978
augcacuacu gcguacucuc cgcauuccuc auacuccacc ucgucaccgu cgccuuaucu       60

uuauccacau gcucaacccu cgacauggac caauucaugc gcaaacgcau cgaagccauc      120

cgaggacaaa ucuuaucaaa acucaaacua accuccccac ccgaagacua ccccgaacca      180

gaagaagucc cacccgaagu cauuuccauu uacaacucca cacgcgaccu gcuacaagaa      240

aaagccuccc gccgcgccgc cgcaugcgaa cgcgaacgcu cagacgaaga auacuacgcc      300

aaagaagucu acaaaaucga caugccaccc uucuuccccu ccgaaaacgc caucccaccc      360

accuucuaca gacccuacuu ccguaucguc cgcuuugacg ucagcgcaau ggagaaaaac      420

gccaguaacc uugucaaagc cgaguuccga guauuccgcc uacaaaaccc aaaagcccgc      480

gucccagaac aacgcaucga acucuaccaa auccuaaaau ccaaagaccu aacuucuccc      540

acccaacgau acauagacuc aaaaguuguc aagacccgcg cagaagguga auggcucagc      600

uucgacguaa cugacgccgu ccacgaaugg cuacaccaua aagaccgaaa ccuaggcuuc      660

aaaauaagcc uccacugccc augcugcaca uucguccccu cgaacaacua uaucaucccg      720

aacaaaucag aggaacugga agcccgcuuc gccggaaucg acggaaccuc caccuacacc      780

uccggcgacc agaaaaccau uaaaucaacc cgcaaaaaga acagcggaaa aaccccacac      840

cuccuacuca ugcuacuacc auccuaccga cuagaaucac aacaaaccaa ccgcagaaag      900

aaacgcgccc ucgaugccgc cuacugcuuc aggaacgucc aagacaacug cugccuacgc      960

ccccuauaca ucgacuucaa acgcgaccuc ggauggaaau ggauccacga accuaaaggc     1020

uacaacgcaa acuucugcgc cggagcaugc cccuaccucu ggagcuccga cacacaacac     1080

ucucgcgucc ucucccuaua caacaccauc aaccccgaag ccuccgccuc acccugcugc     1140

gucucccaag accucgaacc ccucacaaua cuauacuaca ucggcaaaac ccccaaaauc     1200

gaacaacugu ccaacaugau cgucaaaucc ugcaaaugca gcuag                     1245


<210>  979
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  979
augaagaugc accuccaacg cgcccucgua guccucgccc uccucaacuu cgccacaguc       60

agccucuccc uaucaaccug caccacccua gacuucggcc acaucaaaaa gaaaagaguc      120

gaagccaucc gcggccaaau ccucuccaaa cuccgucuca ccagcccacc cgaacccacc      180

gucaugaccc acgucccaua ccaaguccuc gcccuauaca acuccacgcg cgaacuacua      240

gaagaaaugc acggagaaag agaagaagga ugcacccaag aaaacacaga aucagaauac      300

uacgcaaaag aaauccacaa auucgacaug auccaaggac ucgccgaaca caacgaacuc      360

gccgugugcc ccaaaggcau caccucuaaa gucuuccgau ucaacgucuc cucaguagag      420

aaaaaccgca ccaaccucuu cagagccgag uuccgagucc ucagaguccc caaccccucu      480

ucaaaacgca acgaacaacg cauugaacug uuccaaaucc uacgaccaga cgaacacauc      540

gcuaaacaac gauacauagg aggcaaaaac cugcccaccc gaggaacagc agaauggcuc      600

uccuucgacg ucaccgacac cguccgcgaa uggcucuuac gccgagaauc caaccuugga      660

cuagaaaucu ccauacacug ccccugccac accuuccagc ccaacggaga cauacucgaa      720

aacauccacg aagucaugga aaucaaauuc aaaggaguag auaacgaaga cgaccacgga      780

cgcggcgacc ucggccgacu caagaaacaa aaagaccacc acaacccgca ccucauacug      840

augaugaucc caccccaucg ccucgauaac cccggccagg gcggccaacg gaagaaacga      900

gcacucgaca ccaacuauug cuucagaaac cucgaagaaa acugcugcgu cagaccccuc      960

uacaucgacu uccgccaaga ccuaggcugg aaauggguac acgaaccaaa aggcuacuac     1020

gccaacuucu gcagcggacc cugcccauac cuccgaucgg cagacaccac ccacucaacc     1080

guccucggcc ucuacaacac ccuuaacccc gaagcauccg caucccccug cugcguaccg     1140

caagaccuag aaccccucac cauacuauac uacgucggcc gaaccccaaa agucgaacaa     1200

uuauccaaca uggucgucaa auccugcaaa ugcagcuaa                            1239


<210>  980
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  980
auggcaccag uagccgucug ggccgccuug gccguuggcc uagaacucug ggccgcagcc       60

cacgcccugc cagcccaagu cgcauucacc ccuuacgccc ccgaacccgg cagcacaugc      120

cgacuccgcg aauacuacga ccaaacggca cagaugugcu gcucuaaaug cagcccaggc      180

caacacgcaa aagucuucug uacaaaaacc agcgacaccg uaugcgacuc cugcgaagac      240

uccacuuaua cccaacucug gaacuggguc cccgaaugcc ucucuugcgg cagccgcugc      300

ucauccgauc aagucgaaac ccaagccugu acccgcgaac aaaacagaau cuguaccugc      360

agacccggcu gguacugcgc ccucuccaaa caagaaggau gccgacuaug cgccccucuc      420

cgcaaaugcc gcccaggauu cggcguagca cgccccggca ccgaaaccuc agacgucguc      480

ugcaaaccuu gugcgcccgg aacauucagc aacaccaccu cauccaccga caucugcaga      540

ccccaucaaa uaugcaacgu cgucgcuauc cccggaaacg caucaaugga cgcugucugc      600

accucaaccu cucccaccag auccauggca ccaggggccg uccaccuacc ccaacccguc      660

uccacucgau cccaacacac ccaacccaca ccagaaccgu ccaccgcccc auccaccucc      720

uuccuccucc ccaugggccc auccccgccc gccgaagguu cuaccggaga cuucgcccuu      780

cccgucggcc uuaucgucgg ugucaccgca cucggacucc ucaucauagg cgucgucaac      840

ugcgucauca ugacacaagu aaagaagaaa ccacuuugcc uacaacgaga agccaaagua      900

ccccaccucc ccgcagacaa agcccguggc acccaaggac ccgagcaaca acaccuccua      960

auaaccgccc ccucauccuc cuccucauca cucgaaucau ccgccucagc acucgaccgc     1020

agagcgccca cccgcaacca accacaagcc cccgguguag aagccuccgg cgcuggcgaa     1080

gcccgcgccu ccacaggauc uuccgacucu ucacccggcg gccacggcac ccaagucaac     1140

guaaccugca uagucaacgu augcuccucc uccgaccacu ccucacaaug caguucccaa     1200

gcaucaucaa caaugggaga cacagacucc ucccccuccg aauccccaaa agacgaacaa     1260

gucccauuuu caaaagaaga augugccuuc agaucccaac ucgaaacacc agaaacccua     1320

cuuggcucca cagaagaaaa accccucccc cuaggcguuc ccgacgcugg caugaaacca     1380

uccuaa                                                                1386


<210>  981
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  981
augccgguca ugagauuguu cccgugcuuu cuccagcuau uggccggguu agcacuaccg       60

gcagugcccc cacaacagug ggcgcucucg gccgggaacg ggagcucgga aguggaagug      120

guaccauucc aggaagugug ggggcgcucg uacugucgag cgcucgagcg auugguagau      180

gucgugagcg aguacccaag cgagguagag cacauguucu cacccucaug cgugagcuug      240

cucaggugca cgggcuguug cggggacgag aacuugcacu gugucccggu agagaccgcg      300

aacgugacca ugcaacugcu caagaucaga agcggggaca ggcccucgua cguggaauug      360

accuuuagcc agcacgugcg cugugaaugu cgcccgcuca gagaaaagau gaagcccgag      420

cgcagacgac cgaaagggcg cgggaaaagg cgcagggaaa agcaaaggcc cacggacugu      480

cacuugugcg gggacgcggu cccgcgcagg uaa                                   513


<210>  982
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  982
augaccgacc gccagaccga caccgcgccc ucgccaucau accaucucuu gcccggacgc       60

aggagaacag ucgaugccgc ggcaucgcga gggcaaggac cagagcccgc accaggagga      120

ggggucgagg ggguaggagc gcgcggagua gcgcucaaac uguucguaca acugcuaggc      180

ugcaguaggu ucgggggagc ggucguacgc gcgggggagg ccgaaccaag cggcgcggcc      240

agaagcgcaa gcagcggcag ggaagaacca cagcccgagg aaggagaaga ggaagaggaa      300

aaagaagagg aaaggggccc acaguggcga cugggagcgc gcaagcccgg gagcuggacc      360

ggagaagcgg cagugugcgc ggacucggcc ccggcagcac gcgcgccaca ggcccuggcc      420

agagccucag gcaggggcgg gcgcguggcc aggcgcgggg cagaagaauc aggaccgccc      480

cacagcccaa gcaggcgagg gagcgcaagu agggccgggc ccggccgcgc gagcgaaacc      540

augaacuucc uccugagcug gguccacugg ucgcucgcgc uauugcucua ccuccaccac      600

gcgaaaugga gccaggccgc gcccauggca gaaggaggcg ggcagaacca ccacgaggua      660

gugaaauuca uggacguaua ccaaaggagc uacugccacc ccauagaaac gcuuguggac      720

auauuccaag aauaccccga cgaaaucgaa uacauauuca aaccgagcug cgucccacuc      780

augcgcugcg gagggugcug caacgacgaa gggcucgaau gcgugcccac ggaagagagc      840

aauaucacga ugcaaaucau gcgcauaaaa ccgcaccagg ggcaacacau aggggagaug      900

ucguuccuac aacacaacaa augcgaaugc cgacccaaga aagaucgagc acgccaggaa      960

aagaaaucag ucaggggcaa aggaaagggc cagaaaagaa aaagaaagaa aagccgguac     1020

aaaagcugga gcguauacgu gggcgcgcga ugcugccuaa ugccguggag ccuaccggga     1080

ccgcacccau gcggacccug cagcgagaga agaaaacacc uauucguaca ggacccgcag     1140

acaugcaaau gcucgugcaa gaacacagau ucgcgaugca aagcacgaca gcucgagcuc     1200

aaugaaagga caugcagaug ugacaaaccc cgacgcuag                            1239


<210>  983
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  983
augaacuucc uccucuccug gguccacugg ucccuagccc uccuacuaua ccuccaccac       60

gccaaaugga gccaagccgc ccccauggcc gagggcggcg gacaaaacca ccacgaaguc      120

guaaaauuca uggacguaua ccaacgaagc uacugccacc ccaucgaaac ccucguagac      180

auauuccaag aauaccccga cgaaaucgaa uacaucuuca aaccaagcug cguaccccua      240

augcgaugcg gcggcugcug caacgacgaa ggccucgaau gcguacccac cgaagaaagc      300

aacaucacaa ugcaaaucau gagaaucaaa ccccaccaag gccaacacau aggcgaaaug      360

uccuuccucc aacacaacaa gugcgaaugc cgccccaaaa aagaccgcgc ccgccaagaa      420

aagaaauccg uccguggaaa aggcaaaggc caaaaacgaa aacgaaaaaa aagccgcuac      480

aaauccugga gcgucuacgu aggcgcccga ugcugccuaa ugccaugguc ccuccccggc      540

ccccaccccu gcggccccug cuccgaacgc cgaaaacacc ucuucgucca agacccacaa      600

accugcaaau gcuccugcaa aaacacagac ucacgcugca aagcaagaca acucgaacua      660

aacgaacgca ccugccgcug ugacaaacca cgacgauaa                             699


<210>  984
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  984
augucaccac uacuccgccg acuacuccuc gccgcccucc uccaacucgc ccccgcccaa       60

gcccccguca gccaacccga cgccccaggc caccaacgca aagucgucuc cuggaucgac      120

guuuacacuc gcgcaacaug ccaaccccgc gaaguagucg ucccacucac cgucgaacua      180

augggcaccg ucgccaaaca acucgucccc ucaugcguca ccguccaacg cugcggagga      240

ugcugccccg acgacggccu agaaugcguc ccaaccggcc aacaccaagu acgcaugcaa      300

auacucauga uccgauaccc cucaucccaa cuaggcgaga ugucccucga agaacacucc      360

caaugcgaau gccgacccaa aaaaaaagac uccgccguca aacccgaccg agccgccaca      420

ccccaccacc gcccacaacc ccgcuccguc ccaggcuggg acucagcccc cggcgcacca      480

ucacccgccg acaucaccca ccccacaccc gcacccggcc ccuccgccca cgccgccccc      540

ucaaccaccu ccgcacuaac ccccggcccc gccgccgccg ccgccgacgc cgccgcauca      600

ucaguagcaa aaggcggagc auaa                                             624


<210>  985
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  985
augcaccucc ucggauucuu cucaguagcc ugcucccuuc uggccgcagc ccuccucccc       60

ggcccgcgcg aagcccccgc cgccgccgca gccuucgaau ccggccuaga ccugagcgac      120

gccgagcccg acgcaggaga agccaccgcc uaugccucca aagaccucga agaacaauug      180

cgcucggucu cgucagucga cgaacucaug accguccucu acccagaaua cuggaaaaug      240

uauaaaugcc aacuccgcaa agguggcugg caacacaacc gggaacaagc caaccucaac      300

agccgaacag aagaaacaau caaauucgcc gcagcccacu acaacacaga aauccucaaa      360

uccauagaca acgaauggcg caaaacccaa ugcaugcccc gcgaagugug caucgacgua      420

ggcaaagagu ucggcgucgc cacaaacaca uucuucaaac caccgugcgu cuccgucuac      480

cgcuguggcg gaugcugcaa cucggaagga cuacaaugca ugaacacguc caccuccuac      540

cucuccaaaa cccucuucga aauaaccgua ccacuauccc aggguccaaa acccguaaca      600

auauccuucg caaaccauac uuccugccga ugcaugucca aacuugacgu cuacagacag      660

guacacagca uaauccggcg uucccuaccc gcuacccuac cacaaugcca agcagccaau      720

aaaaccuguc caacaaacua cauguggaac aaccacaucu gucgcugccu cgcccaagaa      780

gacuucaugu ucuccucaga cgccggcgac gacucaacag acggcuucca cgacaucugu      840

ggcccaaaca aagaacuuga ugaagaaaca ugccaaugcg ucugccgagc cggacuccga      900

cccgcaagcu gcggccccca uaaagaacua gaccggaacu caugccaaug cguauguaaa      960

aauaaacuau uccccuccca augcggcgcc aaccgggagu ucgacgaaaa uaccugccaa     1020

ugcguaugca aacgcacuug cccacgcaac caaccccuaa accccggcaa augcgccugc     1080

gaaugcaccg aaucgcccca aaaaugccua cucaaaggca agaaauucca ccaccaaacc     1140

ugcuccuguu accgccgacc cugcaccaac cgccaaaaag ccugcgaacc cgguuucuca     1200

uacucagaag aggucugccg augcgucccc agcuauugga aacgcccaca aauguccuaa     1260


<210>  986
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  986
auguaccgug aaugggucgu cgucaacgua uucaugaugc uauacguuca acucguccaa       60

ggauccucaa augaacacgg cccagucaaa cgcagcuccc aauccacacu cgaacgcucc      120

gaacaacaaa uccgcgccgc cuccucccuc gaagaacuac uucgcaucac ccauucagaa      180

gacuggaaac uauggcgaug ccgccuccgc cucaaaucau uuaccucaau ggacagccgc      240

ucagccuccc accgcuccac acgcuucgcg gccacuuuuu acgacauaga aaccuuaaaa      300

gucauagaug aagaauggca acgcacacaa ugcuccccca gagaaaccug cgucgaaguc      360

gccuccgaac ucggcaaauc aaccaacacc uucuucaaac ccccaugcgu caacguauuc      420

cguugcggag gcugcugcaa cgaggaauca uuaaucugca ugaacacaag cacauccuac      480

aucuccaaac aacucuucga aaucucugua ccccucaccu ccguccccga auuaguaccu      540

gucaaagucg caaaccacac aggaugcaag ugccucccua ccgcaccccg ccaccccuac      600

uccauaaucc ggcgauccau ccaaaucccc gaagaagacc gaugcucaca cucaaagaaa      660

cucugcccca ucgacaugcu cugggacucc aacaaaugca aaugcguccu ccaagaagaa      720

aacccccuag ccggcaccga ggaccacucc caccuacaag aaccagcccu cugcggcccc      780

cacaugaugu ucgacgaaga ccgaugcgaa ugcgucugca aaacccccug ccccaaagac      840

cucauccaac accccaaaaa cugcuccugc uucgaaugca aagaaucccu agaaaccugc      900

ugccaaaaac acaaacuauu ccacccagau accugcucau gcgaagaccg cugccccuuc      960

cacacacgcc ccugcgccuc cggcaaaacc gccugcgcca aacacugccg auuccccaaa     1020

gaaaaacgcg ccgcccaagg accccacucc cgcaaaaacc ccuaa                     1065


<210>  987
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  987
auggcgguca uggccccgcg aacgcucgug cucuugcucu caggcgcgcu cgcgcucacg       60

caaacguggg cg                                                           72


<210>  988
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  988
auggacgcga ugaagcgcgg gcucuguugc gugcucuugc ucuguggcgc ggucuuuguc       60

ucgccaucg                                                               69


<210>  989
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  989
augggcgugc acgagugccc ggccuggcuc uggcucuugc ucucgcucuu gagcuugccc       60

uugggcuugc ccgugcucgg g                                                 81


<210>  990
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  990
augaaauggg ucaccuucau cucucuccuc uuccucuucu ccuccgccua cucc             54


<210>  991
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from 
       Artificial____cleavage site-Furin

<400>  991
aggaggagga ggaagagg                                                     18


<210>  992
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  992
auggacuccg acgaaaccgg cuucgaacac uccggccucu gggucuccgu ccucgccggc       60

cuccuccuag gcgccugcca agcacacccc auacccgauu cuuccccacu acuccaauuc      120

ggcggccaag uccgccaacg cuaccucuac acagacgacg cccaacaaac agaagcccac      180

cuagaaaucc gagaagacgg cacagucgga ggcgccgccg accaaucacc cgaaucccuc      240

cuacaacuaa aagcccucaa acccggcguc auccaaaucc ucggcgucaa aaccagccga      300

uuccucugcc aacgccccga cggcgcccuc uacggauccc uacacuucga cccagaagcc      360

ugcuccuucc gcgaacuccu ccuagaagac ggcuacaacg ucuaccaauc agaagcccac      420

ggccuccccc uccaccuccc cggcaacaaa ucaccacacc gcgacccagc cccacgcggc      480

cccgcccgcu uccuuccccu ccccggccuc ccacccgcac uccccgaacc cccaggcauc      540

cucgcacccc aacccccaga cgucggcucc ucagaccccc ucuccauggu cggccccucu      600

caaggcagau ccccauccua cgccuccuaa                                       630


<210>  993
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  993
augcacuccu ucccuccccu ccuacuacuc cucuucuggg gcguugucuc ccacuccuuc       60

cccgcgaccc uagaaacaca ggaacaagac guugaccucg uccaaaaaua ccuagaaaaa      120

uacuacaacc ucaaaaacga cggacgccaa guagaaaaac gacgcaacuc cggccccguc      180

gucgaaaaac ucaaacagau gcaagaguuc uucggccuca aggucaccgg caaacccgac      240

gccgaaacac uaaaaguaau gaaacaaccc cgcugcggcg uacccgacgu cgcccaauuc      300

guacucaccg aagguaaccc acgcugggaa caaacccacc ucacuuaccg gaucgaaaac      360

uacacccccg accucccccg cgccgacguc gaccaugcca ucgaaaaagc cuuccaacuc      420

uggucaaacg ucacaccccu caccuucacc aaagucucug aaggccaagc agacaucaug      480

auaucauucg uacgaggcga ccaccgagac aacucccccu ucgacggccc gggaggcaac      540

cuggcacacg ccuuccaacc agguccagga aucggcggcg acgcacacuu ugacgaggac      600

gagcgaugga ccaacaacuu ccgagaauac aaccuccacc gcgucgcagc ccacgagcuc      660

ggccacucac ugggacucuc acacuccacc gauaucggag cacucaugua ucccucuuac      720

acuuucuccg gcgacguaca acuagcccaa gacgacauag acggaaucca agcaaucuac      780

ggacgcuccc agaaccccgu ccagcccauc ggaccucaaa caccaaaagc cugcgacucc      840

aaacuaacau ucgacgccau cacaaccaua cgaggcgaag ucauguucuu caaagacaga      900

uucuacaugc gcacaaaccc uuucuauccc gaagucgagc ucaacuucau cuccgucuuc      960

uggccccaac uccccaacgg ccuugaagca gccuacgagu ucgccgaccg cgacgaaguc     1020

cgauucuuca aaggaaacaa auacugggcc guccaaggcc aaaacguccu acauggcuac     1080

cccaaagaca uauacuccuc cuucggcuuc ccaagaaccg ucaaacacau cgacgcagca     1140

cucuccgagg aaaacaccgg aaaaaccuac uucuucgucg caaacaaaua cuggcgcuac     1200

gacgaauaca agcgcucaau ggaccccggc uauccaaaaa ugaucgcaca cgacuucccc     1260

ggcaucgguc acaaagucga ugcuguuuuc augaaagacg gcuucuucua cuucuuccac     1320

ggaacccgcc aauacaaauu ugacccaaaa accaaacgca uccucacacu acaaaaagcc     1380

aacagcuggu ucaacugccg caaaaacuaa                                      1410


<210>  994
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  994
augcacuccu ucccaccccu acuccuccua cucuucuggg gcguagucuc ccacucauuc       60

guacucaccg aaggcaaccc ccgaugggaa caaacccacc ucaccuaccg cauagaaaac      120

uacacccccg accucccccg cgccgacgua gaccacgcca ucgaaaaagc cuuccaacuc      180

ugguccaacg uaacaccccu caccuucacc aaagucuccg aaggccaagc agacauaaug      240

auaucauucg uccgcggcga ccaccgagac aacucacccu ucgacggccc cggcggcaac      300

uuagcccacg ccuuccagcc cggcccaggc auaggcggag acgcacacuu cgaugaagac      360

gaacgcugga ccaacaacuu ccgcgaauac aaccuccacc gcgucgcagc ccacgaacuc      420

ggccacuccc uuggacucuc acacuccacc gacaucggag cccuaaugua cccaucauac      480

acauucucag gcgacguaca acucgcccaa gacgacaucg acggcauaca agcaaucuau      540

ggccgcucac agaacccagu acaaccaauc ggcccccaaa cccccaaagc cugcgacucc      600

aaacucaccu ucgacgcaau aaccacaauu cgaggagaag ucauguucuu caaagaccga      660

uucuacaugc gcaccaaccc cuucuacccc gaaguagaac ucaacuucau auccgucuuc      720

uggccucaac uacccaacgg ccucgaagca gcauacgagu ucgccgaccg agacgaaguc      780

cgauucuuca aaggcaacaa auacugggcc guccaaggcc aaaacguccu acacggcuac      840

ccaaaagaca ucuacucuuc cuucggcuuc ccacgaacag uaaaacacau agacgcagcu      900

cucucagaag aaaacaccgg caaaacuuac uucuucguag caaacaaaua cuggcgcuac      960

gacgaauaca aacgcucuau ggaccccgga uaccccaaaa ugauagcuca cgacuucccc     1020

ggcauagguc acaaagucga cgcaguauuc augaaagacg gcuucuucua cuucuuccac     1080

ggcacccgcc aauacaaauu ugaccccaaa accaaacgca uccucacccu ucaaaaagcc     1140

aacuccuggu uuaacugucg caaaaacuaa                                      1170


<210>  995
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  995
augaaaaaga acauccuaaa gauacucaug gacagcuaca gcaaagaauc gaaaauccaa       60

accguucguc gaguaaccuc cguaagccuc cuagccguau aucugaccau gaacacgagc      120

agccucguac uagccaaacc cauagaaaac accaacgaua ccucaaucaa aaacguagaa      180

aaacugagga acgcacccaa ugaagaaaac ucaaagaaag uugaagacag caaaaaugac      240

aaggucgaac acgucaaaaa caucgaagaa gcaaaaguag agcaaguagc ccccgaggua      300

aaaagcaaaa gcacgcucag aucagcaagc auugccaaca caaacagcga aaaauacgac      360

uucgaauacc uaaacggucu aagcuauacc gaacugacga acuuaauaaa gaacaucaaa      420

uggaaccaaa uaaacggccu auucaacuac uccacaggca gccaaaaauu cuucggggac      480

aaaaacagag uacaggcaau aaucaacgcg cuccaggaau ccggccguac cuacacggcg      540

aacgacauga aggggaucga aacauucacc gaaguacucc gugccggcuu cuaccuuggg      600

uauuacaaug acggacucag cuaccucaac gaccgcaacu uucaggacaa gugcaucccc      660

gcaaugaucg caauccaaaa gaacccuaau uucaaauuag gaacagccgu acaggacgag      720

guaaucacga gccugggcaa auuaaucggc aacgccucug cgaacgcaga ggucgucaac      780

aacugugugc caguccucaa gcaguuccgg gagaaccuga aucaauacgc acccgacuac      840

guaaagggca cugccgucaa cgaacucaua aaaggcauag aguucgacuu cucaggcgcc      900

gccuacgaaa aagacguuaa aacgaugccc ugguacggaa aaauagaccc cuucauaaac      960

gaauuaaaag ccuuaggccu cuacggcaac aucaccagcg caacggaaug ggccucagac     1020

guagguaucu acuaucuuuc caaauucgga uuauacagca ccaaccgcaa cgacauagua     1080

caaucccuag agaaagccgu cgauauguac aaauacggaa aaauagcguu cguagccaug     1140

gaacgaauca ccugggacua cgacggcauc ggcucaaacg gcaagaaagu cgaccacgac     1200

aaauuccugg acgacgccga aaaacacuau cuccccaaaa ccuacacauu cgacaacggg     1260

acguucauaa uccgcgcggg cgacaaagua uccgaagaga aaaucaaacg ccuauacugg     1320

gccuccagag aaguuaaaag ccaauuucac cggguggugg ggaacgacaa agcccuagaa     1380

gucggaaacg ccgaugacgu ccucacaaug aaaaucuuca auagucccga agaauacaaa     1440

uucaacacca acauaaacgg cguuagcacc gacaaugggg gccuguacau cgaaccccgg     1500

ggcacauucu acaccuacga aagaacgccu caacaaucua ucuucagucu ggaggaguug     1560

uuccgccacg aauacaccca cuaccuacaa gcacguuacc ucgucgacgg ccuauggggc     1620

cagggacccu uuuacgaaaa gaacaggcua accugguucg acgagggcac agccgaguuc     1680

uucgccggga gcacccgcac auccggagua cugcccagga aaagcauccu cggcuaccuu     1740

gccaaagaua aaguugacca ucgcuacuca cugaagaaga cccuuaacag cggauaugac     1800

gauagcgacu ggauguucua caacuauggg uucgcgguag cacacuaccu auaugaaaaa     1860

gacaugccca cuuucaucaa aaugaauaag gcaauccuca acaccgacgu caaauccuac     1920

gacgaaauca uuaagaaacu gagcgacgac gcaaacaaga acaccgagua ccagaaccac     1980

auccaggagc uagccgacaa guaccagggg gcaggaaucc cccuaguauc agacgacuac     2040

cucaaagauc acggcuacaa gaaagcgagc gaaguauacu ccgaaauauc gaaggcagca     2100

agccucacga acacaagcgu gacagccgaa aaaucacaau acuucaacac cuucacucuc     2160

cgggguaccu acacaggcga gaccuccaag ggagaauuua aagacuggga cgaaaugagc     2220

aaaaagcucg acggcacccu cgaaucacuc gccaaaaacu ccugguccgg cuacaagaca     2280

uuaacugcau acuucacuaa uuaccgcguc accagcgaca acaaagucca auacgacguc     2340

guuuuccacg ggguacuaac cgauaacgca gacaucucca acaacaaagc accuaucgca     2400

aaagucacgg gaccauccac uggggccguu ggacgcaaua uugaguucuc agguaaagac     2460

agcaaagacg aggacggcaa aaucgucagc uacgacuggg auuucggaga cggcgcgaca     2520

ucacgaggca aaaacagcgu ccacgcauau aagaaagccg gcaccuacaa cguuacacua     2580

aaggucacag acgacaaagg agcaacagcg acagagucau ucacaauaga gaucaaaaac     2640

gaggacacga cgacaccuau cacaaaagaa auggaaccga acgacgacau caaagaagcc     2700

aacggcccaa uagucgaagg aguaaccguu aaaggcgacc ucaacggcuc agaugacgcc     2760

gauaccuucu acuucgacgu caaggaagac ggggacguaa caauugaacu accauacuca     2820

gggucaagca auuucacaug gcucgucuac aaagaaggcg acgaucagaa ccauauagca     2880

ucaggcauag acaaaaacaa cucgaaagug ggcaccuuua aaagcacaaa aggccgccac     2940

uacguguuca uauacaaaca cgacagcgcc ucgaacaucu cuuacucacu aaacaucaag     3000

ggccuaggaa acgagaagcu gaaagaaaaa gaaaacaacg acucuucaga uaaggccacc     3060

gucauuccca acuucaacac aacaaugcaa ggcucgcugc ucggcgacga cuccagagac     3120

uauuacuccu ucgagguaaa agaagaagga gaagucaaca ucgaauugga caagaaagac     3180

gaguucgggg ugacauggac ccuucacccg gaauccaaca uaaacgacag gauaaccuac     3240

gggcaaguag auggaaacaa agugucgaac aaagucaagc uccgacccgg caaauacuac     3300

uugcuagucu acaaauacag cggcucuggc aacuacgaac uacgaguaaa caaauag        3357


<210>  996
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  996
augaaauggg ugacuuucau uucccugcug uuccucuuca gcagcgccua cuccaucgca       60

aacacaaaca gcgaaaaaua cgacuucgaa uaccugaacg gacucaguua caccgaacuc      120

acaaaccuca ucaagaacau caaguggaac caaauaaacg gccucuucaa cuacucgacc      180

ggcucccaaa aguucuucgg ggauaagaac cgcguccaag ccauuaucaa cgcccuccaa      240

gaaagcgggc gcacauacac cgccaacgac augaagggca uagaaacauu uacagaagug      300

cuacgcgcgg gcuucuaccu cggcuauuac aacgacggac ucagcuaccu aaacgaccga      360

aacuuccagg acaagugcau accggcaaug auagccaucc agaaaaaucc caacuuuaaa      420

cucggaacug ccgugcaaga cgaaguaauc accucgcucg gaaaacuaau cggcaacgcc      480

ucagccaaug ccgaaguagu caauaacugc guccccgucu uaaagcaauu ccgagagaac      540

uugaaccaau acgcaccaga cuacgucaag ggcaccgccg uaaacgaguu aaucaaaggg      600

auagaguucg acuucucggg agccgcauau gaaaaagacg ucaaaaccau gccaugguac      660

ggcaaaaucg accccuucau aaacgaacuc aaagcccuug gccuauacgg caacauaaca      720

agcgcgacag aaugggccag cgacguaggc aucuacuacc uaucaaaguu cggacucuac      780

agcaccaacc ggaacgacau aguccaaagc cucgaaaaag caguagacau guacaaauac      840

ggcaaaauag ccuucgucgc aauggagcgc auaacauggg auuacgacgg gaucggcagu      900

aaugguaaga aaguagacca ugacaaguuc cucgacgacg cagaaaaaca cuaccuaccu      960

aagacauaca ccuucgacaa cggaaccuuc auaauccgcg caggcgacaa aguuagugag     1020

gagaaaauca aaagacuaua cugggcauca agagaaguca aaucacaauu ccaccgcgua     1080

gucggcaacg acaaagcccu cgaagugggg aacgccgacg acguccuaac aaugaaaauc     1140

uucaacagcc ccgaagaaua caaauucaau acuaauauaa acggaguaag cacagacaac     1200

ggcggccuau auaucgaacc ccgcgggacu uucuauaccu acgaaaggac gccgcaacaa     1260

uccauauucu cacuagaaga acuauuccgc cacgaauaca cccacuaccu ccaggcaaga     1320

uaccuagucg acggccuaug gggucagggc ccauucuacg aaaagaaccg ccuaaccugg     1380

uucgacgagg gaacagccga auuuuucgcc ggauccaccc gcacaagcgg aguccugccc     1440

cgcaaaucaa uacucgggua ccuagcgaaa gacaaagugg accaccgaua cagccuaaag     1500

aaaacacuca acuccggaua cgaugacagc gacuggaugu ucuacaacua cggauucgcc     1560

gucgcacacu accuauacga gaaagacaug cccacuuuca ucaaaaugaa caaagcgaua     1620

cucaacaccg acgucaaaag cuacgacgag aucaucaaga aacuguccga cgacgcaaau     1680

aaaaacaccg aauaccagaa ccacauucag gaacucgccg acaaauacca aggagccggc     1740

aucccacucg ucagcgacga cuaccucaaa gaccacgggu acaaaaaggc guccgaagua     1800

uauucugaga ucagcaaagc cgcaucccug accaacacau cagucacagc agagaaaucu     1860

caguacuuca acacauucac gcuccggggg accuacacag gcgaaacuag caaaggggag     1920

uucaaggacu gggacgagau gagcaagaaa cuggauggca cacucgagag ucucgcgaaa     1980

aacuccuggu cgggcuacaa aacgcuuaca gcauauuuca ccaacuaccg cgucaccuca     2040

gacaacaaag uccaauacga cgucguguuc cacggagugc ucaccgacaa cgccgacauc     2100

uccaacaaca aggcaccuau cgcaaaggug accggccccu caacaggcgc gguuggacgg     2160

aacaucgagu ucuccgggaa agacaguaag gacgaggacg gcaaaauagu aagcuacgac     2220

ugggacuucg gagacggggc gaccucccga ggcaagaaca gcguccacgc cuacaagaaa     2280

gccggcacau acaacgugac acuuaaaguu accgacgaca aaggagccac cgccacggag     2340

uccuuuacca ucgagaucaa aaacgaagac accacaaccc caauaaccaa agaaauggaa     2400

ccuaacgacg acauuaagga ggcaaacggc ccaauaguag aaggaguuac ggucaagggu     2460

gaccucaacg guuccgauga cgcagacacc uucuacuucg acgucaaaga agacggggau     2520

guaaccaucg aacuacccua cuccggaucc ucaaauuuca cuuggcuagu auacaaggag     2580

ggcgacgacc aaaaccacau agccucgggg auagacaaaa acaacucuaa aguaggaacc     2640

uuuaagucca caaagggacg gcacuacguc uuuaucuaca agcacgacuc cgcuuccaac     2700

auaucguacu cguuaaacau caaaggacua ggaaacgaaa aacucaaaga gaaagaaaac     2760

aacgacucau cggacaaagc gacaguaaua ccaaacuuca acaccacgau gcagggcucc     2820

cuauugggag augacagccg agacuacuac ucguuugaag uaaaagagga aggcgaaguc     2880

aacaucgaac uagauaagaa agacgaguuc ggaguuacgu ggacccucca ccccgagagc     2940

aacaucaaug accgaauuac cuauggccag gucgacggua acaaaguauc uaauaaaguc     3000

aaacuccgcc caggcaaaua cuaccuccuc gucuacaagu acagcgguag cggcaacuac     3060

gaacuacgcg ugaauaaaua a                                               3081


<210>  997
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  997
augaaguggg ugacauucau cucccuacug uucuuauuua guuccgccua uaguaugaaa       60

aagaacauuc ucaaaauccu cauggacagc uacagcaaag agagcaagau ccagaccgug      120

cgucgaguaa ccagcgucag cuuacuagcg guauaccuaa ccaugaacac auccagccua      180

guccuggcaa aacccaucga aaacaccaau gacacuucca ucaagaacgu cgagaagcua      240

cgaaacgcac caaacgaaga gaauagcaag aaaguugaag auuccaaaaa ugacaaagua      300

gagcacguca aaaacaucga agaagcaaaa gucgaacaag uagccccgga agucaaaucc      360

aagagcacgc uccgcuccgc caguagacgg cgcaggaaac gcaucgcaaa cacaaacucc      420

gagaaauacg acuucgaaua cuugaacgga uuaagcuaca cggagcuaac caaccucauc      480

aaaaauauaa aauggaacca aauaaacggc cuauucaacu auagcaccgg gucccagaaa      540

uucuucggag auaagaaccg cguacaagcu aucaucaaug cccugcagga auccggccgc      600

acauacacgg ccaacgacau gaaagguaua gaaacauuca cagaagugcu aagggccggc      660

uucuaccucg gcuacuacaa cgacgggcua ucauaccuaa augacagaaa uuuucaggac      720

aaaugcauac cggcuaugau cgcgauacag aaaaacccga acuucaagcu aggcacggcc      780

guacaagacg aagucaucac cuccuuggga aaacucauag gcaacgccuc cgcgaacgcc      840

gaagucguca acaacugugu acccguccua aaacaguuua gagagaaccu aaaccaguac      900

gcuccggacu acgucaaagg gacagcagug aaugaacuga uuaagggaau agaguucgac      960

uucucaggcg cugccuacga aaaggacgug aaaaccaugc ccugguacgg caagaucgac     1020

ccauucauca acgaauuaaa agcacucggc cuauauggca acauaaccuc cgccaccgaa     1080

ugggcaucgg acgucggaau auacuaccuc aguaaauuug gacuguauag caccaacaga     1140

aacgacaucg uccaaagccu cgagaaagca gucgacaugu acaaauacgg caaaauagcc     1200

uucguggcaa uggaaaggau cacaugggac uacgacggca ucggguccaa cggaaagaaa     1260

guagaccacg acaaauuucu ugacgacgcc gagaaacacu accuaccaaa aacuuacacc     1320

uucgacaacg gcaccuucau aaucagagca ggagacaaag ucagcgaaga gaaaaucaaa     1380

cggcuuuacu gggccucacg ugaagugaaa agccaguucc accgcgucgu gggaaaugac     1440

aaggcauugg aaguagggaa cgcggacgac guccuaacaa ugaaaauauu caacagccca     1500

gaagaauaca aauucaacac uaacauaaau ggagucucca ccgacaacgg cggccucuac     1560

auagaaccaa ggggcaccuu uuacacauac gaacgcacac cucagcaaag cauauuuuca     1620

cuagaagaac ucuuccguca cgaauacacc cacuaccucc aggcuagaua ccucguugac     1680

ggacuguggg gccagggccc cuuuuaugag aaaaaccgcc ucacgugguu cgacgaaggc     1740

acagccgagu ucuucgccgg cagcacacga accagcggcg uacuaccacg aaaaucgauc     1800

cucggcuacc uggcaaaaga caaagucgau cauagguaca gccucaaaaa gacacuaaac     1860

agcggauaug acgacucuga cuggauguuu uacaacuacg gguucgccgu cgcacacuac     1920

cucuacgaaa aggacaugcc cacauucauc aaaaugaaca aggcgauccu aaacacugac     1980

guaaaaagcu acgacgaaau aauaaagaag cuaagcgacg augccaacaa gaacacagag     2040

uaccaaaacc acauucagga acuugccgac aaauaccagg gagccggaau cccgcucgua     2100

uccgacgacu accuaaaaga ccacggauac aaaaaggcau ccgaagucua cagcgaaaua     2160

agcaaggccg cgucacuaac aaacacguca gucaccgcag agaaauccca auacuucaac     2220

accuuuacac ugagagggac auacaccggc gaaaccucaa aaggagaguu caaagacugg     2280

gacgaaaugu ccaagaaacu agacggaaca cucgaaucgc uagcuaaaaa cuccuggagc     2340

ggauacaaaa cccucacggc uuauuucacc aacuaccgcg ucacgagcga caacaaggua     2400

caauaugacg uugucuucca cggcguccuc acggacaacg ccgacaucuc aaacaauaag     2460

gcccccauag caaaaguaac aggaccaucc accggcgcag ucggccgaaa cauagaguuc     2520

ucaggcaaag auuccaaaga cgaagacggg aaaaucguua guuacgauug ggacuucggc     2580

gacggcgcca ccucgcgagg uaagaacucc gugcacgcau acaaaaaggc cggaaccuac     2640

aacguuaccc uaaaggugac agacgacaaa ggagcgacgg cgacagaauc uuucacaauc     2700

gaaaucaaaa acgaagacac uacaacaccc aucacgaaag aaauggagcc caacgacgac     2760

aucaaggaag caaacgggcc gaucguugaa ggaguaaccg ucaaaggaga ccucaacggg     2820

agcgacgacg cagacaccuu cuacuucgau gucaaagagg acggggacgu aacaaucgag     2880

cuccccuacu caggaagcag caacuucaca uggcuagugu acaaggaggg cgacgaccag     2940

aaccacauag cguccggcau cgacaaaaac aacucaaaag uaggcaccuu caaaaguacc     3000

aaaggccgcc acuacguuuu caucuacaag cacgacuccg ccuccaacau aagcuacucg     3060

cuaaacauca agggcuuagg caacgaaaaa cugaaagaaa aagaaaacaa cgacucaucu     3120

gacaaggcca ccguaauacc caauuucaac acaaccaugc agggcucacu gcucggagac     3180

gacucacgag auuacuacuc cuuugaagua aaagaagaag gcgaaguaaa caucgaauug     3240

gauaagaaag acgaguucgg cgugacgugg acacuucacc cagaaucaaa caucaacgac     3300

aggauaaccu augggcaagu agacggcaac aaaguaucua acaaggucaa gcuccgcccc     3360

ggcaaguacu accugcucgu cuacaaauac agcggaucug gaaacuauga acuccgcgua     3420

aacaaauaa                                                             3429


<210>  998
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  998
augaacuucc ucaaaaucau acugaaccgc ggaaaaacca ugaagagaaa gugccuaucc       60

aaaagguuaa ugcucgccau aaccauggcc acgauauuca cagugaacuc gacccucccg      120

auuuacgccg ccguagacaa aaacaacgcg accgccgcgg uacagaacga guccaaacgg      180

uacacgguau ccuaucucaa gacccucaac uacuacgacu uggucgaccu ucucgucaaa      240

acagagauag aaaaccuucc cgaucuauuc caauacucua gcgacgccaa agaguucuac      300

ggaaacaaaa caagaauguc guucaucaug gacgagaucg gccgccgcgc uccucaauac      360

acagaaauag accacaaagg cauacccacc cuggucgagg ucguccgcgc cggcuucuac      420

cuagguuucc acaacaaaga acuaaacgaa aucaacaagc gcagcuucaa agaaaggguc      480

auacccucca uacuggcuau ccagaaaaac cccaacuuca aauugggaac cgaaguacaa      540

gacaaaauag ucucagccac aggccugcuc gcagguaacg agacugcacc accggaagug      600

guaaauaacu ucaccccgau acuccaagac uguaucaaga acaucgaccg uuacgcccuc      660

gacgaucuca aaagcaaagc acucuucaac gugcucgcag caccaacgua ugauaucacu      720

gaauaccuga gagcaaccaa agaaaaaccg gagaacaccc ccugguacgg gaaaaucgac      780

ggguucauaa acgaauugaa gaaacuggcc cuuuacggca aaauaaacga caauaacuca      840

uggauaaucg acaacggaau cuaccacaua gcaccccucg gcaaacucca caguaacaac      900

aaaauaggga ucgagacccu aaccgaagug augaagguuu accccuaucu cucaaugcag      960

caucuccaga gugcagacca aauaaaaagg cauuacgacu caaaagacgc cgagggcaac     1020

aagauaccuc ucgacaaguu caagaaagag ggcaaagaaa aguacugccc caaaaccuac     1080

acguuugacg augguaaagu caucauaaag gcaggagcac gagucgaaga agaaaaaguc     1140

aaacgucuuu acugggccag caaggaagua aacagccagu ucuuccgagu cuacggcauc     1200

gacaaaccac ucgaggaagg caacccggau gacauccuca caauggugau cuacaacagc     1260

ccggaggagu acaaacuuaa cuccgucuug uacggcuaug acaccaacaa uggcgggaug     1320

uacaucgaac cagaaggaac uuucuucacc uaugagcgcg aagcccaaga guccaccuau     1380

acccucgagg aacucuuccg acacgaauac acucauuacu uacaaggccg cuacgcagua     1440

cccgggcaau ggggccgcac caagcuauac gacaaugaca gacuaacuug guacgaggaa     1500

ggcggagccg aacuauucgc aggcuccaca cgcaccucag gaauacuccc ucgcaaaagc     1560

auaguaucca acauacacaa caccacccga aacaacagau auaaacuaag cgacaccguc     1620

cacagcaaau acggagcgag cuucgaguuc uacaacuacg ccugcauguu uauggacuau     1680

auguacaaca aagauauggg cauacucaac aaacuuaacg accuagcaaa gaacaacgac     1740

gucgacggcu acgacaacua cauacgggac cucagcucga acuaugcacu aaacgacaaa     1800

uaccaagacc acaugcagga acgcauagac aacuacgaaa accucaccgu acccuucguc     1860

gcagacgacu accuaguccg acacgcguac aaaaauccca acgaaaucua cuccgaaauc     1920

agcgaagucg ccaagcugaa ggaugccaaa agcgaaguga agaaaucaca auauuucuca     1980

accuucacgc uccgcggcuc auacacaggu ggcgccucca aaggaaaacu agaggaucaa     2040

aaagcaauga acaaguucau agacgacucc cucaaaaagc ucgacacaua cuccuggucc     2100

ggcuacaaaa cacuuaccgc guacuucacc aacuacaaag uagacuccuc gaaucgagua     2160

accuacgacg ucguauucca cggcuaccuu ccaaacgaag gcgacuccaa aaacucccua     2220

cccuacggaa agauaaacgg caccuacaaa gguaccgaaa aggagaaaau caaauucucc     2280

agcgaagggu cauuugaccc agacggaaaa aucgucuccu acgaauggga cuucggagac     2340

ggaaauaagu caaacgaaga aaaccccgaa cacagcuacg acaaaguggg aaccuacacc     2400

guaaagcuca aagugacaga ugacaaaggc gaaucaagug uaaguacgac cacugcugag     2460

auaaaagacu ugucggagaa uaaacuuccc guaaucuaca ugcacguccc caaaucagga     2520

gcacuaaacc agaaagucgu auucuacggc aaaggaaccu acgaccccga cggcucaaua     2580

gccggauauc aaugggauuu cggggacgga agcgacuuuu cgucggaaca gaaccccagc     2640

cacguguaca cgaagaaagg ggaauacacc gucacccugc ggguaaugga cagcucaggc     2700

caaauguccg agaaaacaau gaaaauaaaa aucaccgacc ccgucuaccc caucggcacg     2760

gaaaaagaac ccaacaacuc caaagaaacc gcauccggcc caaucgugcc cggcauaccc     2820

gucuccggca caauagaaaa uaccuccgac caagacuacu ucuauuucga ugucaucacc     2880

cccggagagg ucaaaaucga caucaacaaa cugggcuacg gcggagcaac cuggguaguc     2940

uacgacgaga acaacaacgc cgucaguuac gcaaccgacg acgggcaaaa ccucagcgga     3000

aaguucaaag ccgacaaacc aggaagauac uacauccacc uauacauguu caauggcagc     3060

uacaugcccu acagaauuaa uaucgaggga uccgugggcc gcuaa                     3105


<210>  999
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  999
augaaacgaa aaugccuuag caaacgccug augcucgcca uuaccauggc gacaauauuc       60

accgugaaca guacgcuccc uaucuacgca gccguagaca aaaacaacgc aaccgcagcc      120

guacagaacg aguccaaacg cuacaccguc uccuaucuca agacccuaaa cuacuacgac      180

cuuguagacc uccucgugaa gaccgaaauc gaaaaccuac ccgaccucuu ccaauacucc      240

agcgacgcca aggaguucua cggaaacaaa acccgaauga gcuucauaau ggacgaaauc      300

ggucgccgcg cgccccaaua cacggaaauc gaccauaaag gaaucccuac cuuagucgag      360

gucguaagag cggguuucua ccuaggauuc cacaacaaag agcuaaacga gaucaacaaa      420

cgcuccuuca aagaacgcgu gauccccucu auccuagcca uccagaaaaa cccaaauuuc      480

aaacucggca ccgaaguaca agauaaaaua guaagcgcca ccggacuccu cgcuggcaac      540

gaaaccgcac ccccagaagu agugaauaac uucacaccca uccuccaaga uugcaucaaa      600

aauauagacc gauacgcccu ggacgauuua aaaagcaaag cacucuucaa cguacucgcu      660

gcacccacau acgacaucac agaguacuug agggcaacga aagagaaacc cgaaaacacc      720

cccugguacg gaaaaauaga cggcuucauc aacgaacuaa agaaauuggc gcuauauggg      780

aaaaucaacg acaacaacag uuggauaauc gacaacggca ucuaucacau agcaccccuc      840

ggcaaacucc auagcaacaa caaaauaggc auagaaacac uaacugaagu caugaaagua      900

uaccccuauc ucagcaugca acaccuacaa uccgccgacc aaaucaaacg ccacuacgac      960

agcaaagacg cagaaggcaa caaaauaccc cucgacaagu ucaagaaaga aggaaaagag     1020

aaauacugcc ccaaaaccua caccuucgac gacggcaaag uaaucaucaa ggccggagca     1080

cgaguagaag aagagaaagu aaaacgacuc uacugggcga gcaaagaagu caauagccaa     1140

uucuuccgcg uuuacgguau cgauaaaccg cuugaagaag gcaacccaga ugacauccua     1200

acgaugguua ucuauaacag ucccgaagaa uacaaacuca acagcguccu uuauggguac     1260

gacaccaaua acggcgggau guacaucgaa cccgagggga ccuucuucac auacgaacga     1320

gaagcccaag aauccaccua cacacuagaa gaacucuucc gccacgaaua cacccacuau     1380

cuucagggca gauacgccgu accaggacaa ugggggagga ccaaauuaua cgacaacgac     1440

cgacucacau gguacgaaga aggcggcgcc gaguuauucg cuggaaguac ucgaaccucc     1500

ggcauccuuc cccgaaaaag cauagucucg aacauccaca acacaacccg uaacaaucgc     1560

uacaaacuau ccgauacagu ccacagcaaa uauggagcua gcuuugaguu cuacaacuau     1620

gccugcaugu ucauggacua cauguacaac aaggacaugg gcauccucaa caaacuaaac     1680

gaccuggcga aaaacaacga cguagacggc uacgacaacu acauacgcga ucuuagcucu     1740

aacuacgccc uaaacgacaa auaucaagac cauaugcagg aacggaucga uaauuacgaa     1800

aaucucacag uacccuucgu cgccgacgac uaccuagucc ggcaugcaua caaaaacccg     1860

aaugagauau acuccgagau cucagaaguc gcaaaacuga aagacgcaaa gucggaaguu     1920

aaaaagagcc aauacuucag cacauucacc cuccgcggau cuuacaccgg cggggccucc     1980

aaggggaaac uugaggacca aaaagcaaug aacaaauuua ucgacgacag ccucaaaaag     2040

cucgacaccu acagcuggag cggguacaaa acacuuacgg cauacuucac caauuacaaa     2100

gucgacucga gcaaucgggu caccuacgac guggucuucc acggcuaccu accgaacgaa     2160

ggcgacagca aaaacucacu accguacggc aaaauaaacg gcacguauaa agggaccgaa     2220

aaagaaaaga ucaaguucuc aucagaaggc uccuucgacc cagacggaaa aauagugagc     2280

uaugaguggg auuucggcga cgggaacaaa ucaaacgaag agaacccgga gcacagcuac     2340

gacaaagucg ggaccuacac cgucaaacua aaagucaccg augacaaagg cgaguccuca     2400

guauccacga ccacggcuga aaucaaagac cugagcgaaa acaagcuccc agucauauac     2460

augcacgucc cgaaauccgg cgcccuaaac cagaaagucg ucuucuacgg caaaggcacu     2520

uacgacccag acggcagcau agcaggauac caaugggacu ucggggacgg cuccgacuuc     2580

ucaucagaac agaacccauc acacgucuac accaaaaagg gcgaguacac aguuacacuc     2640

cgcgugaugg acuccuccgg acaaaugagc gagaaaacaa ugaaaauaaa aauaaccgac     2700

ccgguauacc caauaggcac ggaaaaggaa ccuaacaaca gcaaagaaac agcaucaggu     2760

cccauuguac ccggcauccc agucucagga accaucgaaa acaccuccga ccaagacuac     2820

uucuacuucg auguaauaac acccggcgaa guaaaaaucg acaucaacaa acucggguac     2880

gggggagcaa ccugggucgu auacgaugaa aacaacaacg cugucucaua cgcaaccgac     2940

gacggacaga accugagcgg caaguucaaa gccgacaaac cagggaggua cuacauacac     3000

cucuacaugu ucaaugguag cuacaugccu uaccguauaa auaucgaagg aucuguagga     3060

cgauaa                                                                3066


<210>  1000
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  1000
augaaauggg ugaccuucau aagccuucuc uuccucuucu cauccgccua cagcguacaa       60

aacgagucga aaagauacac cguaucauac cucaagaccc ucaacuacua cgaucucguc      120

gaucuauuag ucaagacaga aaucgaaaau cuacccgacc uauuccagua cucaucggac      180

gccaaagagu ucuacggcaa caaaacacga augagcuuca uuauggacga aauagguaga      240

cgagcgccgc aguacacgga aaucgaccac aaagggaucc ccaccuuagu cgaaguugua      300

cgcgcgggcu ucuaccuagg auuucacaac aaagaacuua acgaaaucaa caaacgcagu      360

uucaaagaac gcgucauccc cagcauccua gcgauccaga aaaaccccaa uuuuaaacuc      420

ggcaccgaag uacaggacaa gauaguguca gcaacaggcc ugcucgccgg aaacgaaacg      480

gccccacccg aaguagucaa uaacuucaca cccauacugc aggacugcau caaaaauauc      540

gaccgauacg cacucgacga ccucaagagc aaagcccucu ucaacgugcu cgccgcccca      600

accuacgaca uaaccgaaua cuugagggcc acaaaagaaa aacccgaaaa caccccaugg      660

uacggcaaaa uugacggauu caucaacgag cugaagaaac ucgcccucua cgggaaaauc      720

aaugacaaca acagcuggau caucgacaac ggcaucuacc acauugcccc gcuaggcaaa      780

cuacacucca acaacaaaau cggcaucgaa acgcucacgg aagucaugaa aguauaucca      840

uaucuaucca ugcaacaccu ccaaucugcc gaccaaauca aacgccacua cgacagcaag      900

gacgcggaag gaaacaaaau cccacucgac aaguuuaaga aggaaggcaa agaaaaauac      960

ugcccuaaaa ccuacacguu cgaugacggg aaaguaauua ucaaagccgg cgcccgaguc     1020

gaagaggaaa aggugaaacg ccuauacugg gccuccaaag agguuaauuc acaauuuuuc     1080

cgagucuaug gcaucgacaa accacucgag gaagguaacc ccgacgauau ccucaccaug     1140

guaauauaua auucgcccga ggaauauaaa cucaacagcg ucuuauacgg cuacgacacc     1200

aacaacggug gcauguacau cgagccggaa ggcaccuucu ucaccuacga gcgugaagcc     1260

caagaaucca cguacacacu ugaggaacua uuccgacaug aauacaccca cuaccugcaa     1320

ggccgguacg caguaccugg ccaguggggc cgcacuaaac ucuacgacaa cgaccgucuc     1380

accugguacg aagaaggugg agccgaacuc uucgccggcu ccacccgcac cagcggcauc     1440

cuaccccgaa aauccauagu cucgaacauu cacaacacaa cccgaaauaa ccgcuacaaa     1500

cucagcgaca ccguacacuc aaaauacgga gccagcuucg aguucuacaa cuacgcgugc     1560

auguucaugg acuacaugua caacaaagau auggggauuc uaaacaaacu uaacgaccuc     1620

gccaaaaaua acgacgucga cgguuacgac aacuauauac gagaucuuuc aucgaacuac     1680

gcacuaaacg acaaauacca ggaccacaug caagaacgca ucgacaacua cgaaaaccuc     1740

accguccccu ucgucgcaga cgauuaccuc guccgacacg cauacaagaa ccccaacgaa     1800

auauacucgg agaucagcga agucgccaag cucaaagaug caaaauccga agucaaaaag     1860

ucacaguacu uuagcacauu cacacuccgc gggagcuaca ccggcggcgc guccaaggga     1920

aagcucgaag accaaaaagc caugaacaaa uuuauagacg acucccucaa gaaacucgac     1980

accuacucgu ggagcggcua caaaacacuu accgcauacu ucaccaacua caaaguagac     2040

agcucaaauc ggguaacuua cgacguaguc uuccacggcu accuucccaa ugaaggagac     2100

agcaagaacu cacucccuua cggcaaaaua aauggaacgu acaagggcac ggaaaaggag     2160

aaaaucaaau ucagcuccga aggcuccuuc gaccccgacg gaaaaauagu aucauacgaa     2220

ugggacuucg gcgacggcaa caagaguaac gaagaaaauc ccgaacacuc auacgacaaa     2280

gucggcacgu acaccgucaa acuaaaagua acagacgaca aaggcgaauc cucagugagu     2340

acgaccaccg cagaaaucaa agacuuauca gaaaacaaac uccccguaau auacaugcac     2400

gucccaaaga gcggggcacu caaccaaaaa gucgucuucu acggcaaagg aaccuacgac     2460

ccugacggau ccaucgccgg cuaccagugg gauuucggcg acggaagcga cuucucaucg     2520

gagcaaaacc caagccacgu cuacacgaaa aagggagaau acacagugac acuccgagua     2580

auggacuccu cagggcagau guccgagaaa accaugaaaa uaaagaucac cgacccuguc     2640

uaccccaucg gaaccgaaaa ggagccuaac aauuccaaag aaaccgccag cggaccaaua     2700

guacccggua uccccgucuc cggaaccauc gaaaacacgu cagaccagga cuacuucuac     2760

uucgacguca uaaccccggg cgaaguaaaa aucgacauca acaaacuagg cuacggcgga     2820

gccacauggg ucguauacga cgaaaacaac aacgcgguau cuuacgcaac agacgacggc     2880

caaaaccuaa gcggcaaguu caaagcagac aaacccgggc gcuacuacau ccaccuguac     2940

auguucaacg gaagcuacau gccauacaga auaaauaucg aaggcuccgu aggacguuaa     3000


<210>  1001
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  1001
augaaauggg ucaccuucau cucucuacug uuccucuucu cuagcgcaua uagcaugaaa       60

cggaaauguc uauccaaacg ccugaugcug gccauuacga uggccaccau cuucaccguc      120

aacucuaccc ugccgaucua cgccgccgua gacaagaaca acgccaccgc cgcucgccgc      180

cgaagaaaga ggguccaaaa cgaaagcaaa agauacacag uaagcuaccu uaagacacuc      240

aacuacuacg accucguaga ccuacucguc aagacagaaa uugagaaccu ccccgaccua      300

uuccaauaca gcagcgacgc caaagaguuc uacggcaaca aaacccgaau gucuuucaua      360

auggaugaaa uaggacgcag agcgccccaa uacacggaaa ucgaucacaa aggcauaccc      420

acccuagugg aagucguacg agcuggcuuc uaucuggguu uccacaacaa agaacugaac      480

gaaauaaaca agcgcagcuu caaagaacgc gugauccccu caauacuggc uauccagaaa      540

aaucccaauu ucaaacuagg gaccgaaguc caagacaaga ucguguccgc gacaggacuc      600

cucgccggca acgaaaccgc cccgccggaa gucguuaaca acuucacgcc aauacuacaa      660

gacugcauua aaaacaucga ccgauacgcc cuagacgauc ugaaauccaa ggcacuauuc      720

aacguucugg ccgcaccaac auacgacauc acagaguacc ugcgugccac aaaagaaaaa      780

ccagaaaaua cccccuggua cggcaaaauc gacggauuca uuaaugaguu gaaaaagcua      840

gcacucuacg gaaaaaucaa cgacaauaac agcuggauca ucgacaacgg cauuuaccac      900

auagcgcccc ucggcaaacu gcacuccaac aacaaaaucg guauagagac acucacagag      960

gugaugaaag uuuacccaua ccuaagcaug caacaccuuc aauccgccga ccaaaucaaa     1020

cgccacuacg acuccaaaga cgcggaaggc aacaaaauac cccucgacaa auuuaaaaag     1080

gagggcaaag aaaaauacug cccaaagacc uacaccuucg augacggcaa aguaauaauc     1140

aaagcaggag ccagagucga ggaggagaag gucaaaaggc uauacugggc aucuaaggaa     1200

gugaacagcc aauucuuucg gguauacgga aucgacaagc cccuagaaga agguaacccc     1260

gacgacaucc uuacaauggu aauauacaac agcccggaag aguacaaacu caacaguguu     1320

cuauacggau acgauacgaa caacggaggc auguacaucg aaccggaggg caccuucuuc     1380

accuacgagc gagaggccca agaaagcaca uacaccuuag aagaacuguu ccgacacgaa     1440

uacacccauu accuccaagg cagauacgcu guccccggcc aauggggacg cacuaaacua     1500

uacgauaacg accgccuaac augguacgaa gaggguggcg ccgaacucuu cgccggcuca     1560

acgagaacga gcggaauccu gccgcgcaaa agcaucguca gcaacauaca caacacaacg     1620

cgaaacaauc guuacaaacu cucggacacg guccacucaa aauacggcgc gucauucgag     1680

uucuacaacu acgccugcau guucauggau uacauguaca auaaggacau gggcauccua     1740

aacaaacuca acgaccucgc uaaaaacaac gacgucgacg gcuacgacaa cuauauccga     1800

gaccuaagcu cgaacuacgc acucaaugac aaauaccaag accacaugca agagcgcauc     1860

gacaacuacg aaaaccuaac aguacccuuc guugcggacg acuaucucgu caggcacgca     1920

uacaagaacc caaacgagau auacagcgaa aucagcgagg uagccaaacu uaaggacgcc     1980

aaauccgaag ucaagaaauc gcaguacuuc ucaaccuuca cgcuacgugg cagcuacacc     2040

gggggagcaa gcaaaggaaa acucgaggac caaaaagcaa ugaacaaguu uauugacgac     2100

agccuaaaga aacuagauac auauuccugg uccggcuaca aaacgcuaac ggcauacuuc     2160

acgaacuaca agguugacuc aaguaaccgc guaacauacg acguaguuuu ccacggauac     2220

cuaccaaaug aaggcgacuc caaaaacucg cugccauacg gaaaaaucaa uggcacauac     2280

aaagggacag agaaggagaa aaucaaauuc aguucagaag gauccuucga cccagacggc     2340

aaaaucguuu cauaugaaug ggauuucgga gacgggaaca aaucaaacga agaaaacccu     2400

gagcacagcu acgacaaagu cggcacauau acaguaaagc ucaaagucac ggacgacaag     2460

ggcgagagca gcguaagcac gaccaccgca gaaaucaagg accucuccga aaauaaacuc     2520

ccagucauau acaugcacgu accaaaaucg ggcgcccuca accagaaagu aguguucuac     2580

ggaaaaggca cauacgaucc ggacggaucc auagcaggcu accaauggga uuucggagau     2640

gggagcgacu ucucgagcga acaaaacccg ucacacgucu acacuaaaaa gggcgaguac     2700

accguaaccc uucggguaau ggacuccucc ggacaaaugu cugagaaaac caugaaaauc     2760

aagauaaccg acccaguaua ccccaucggc accgaaaaag aaccaaacaa cuccaaagaa     2820

acugccuccg gccccaucgu accgggaauc ccagucuccg gcaccaucga aaacaccagc     2880

gaccaagauu acuucuacuu cgacguaauc acccccggag aagucaaaau cgacaucaac     2940

aaacugggcu acggaggagc uaccugggua gucuacgacg aaaacaacaa cgccgucagu     3000

uacgccaccg acgacgggca aaaccugucc gguaaauuua aggccgacaa gccagggcga     3060

uacuacaucc accuguauau guuuaacgga uccuauaugc ccuaccgaau aaauaucgaa     3120

ggaaguguag gccgcuaa                                                   3138


<210>  1002
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  1002
augggaacau ggauacucuu cgcaugccuc cucggcgcag ccuucgccau gccccucccu       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg aaguccucac accccucaaa      120

ugguaucaau ccaucagacc acccuacccc uccuacggcu acgaacccau gggcggcugg      180

cuccaccacc aaaucauccc cguccucuca caacaacacc cucccaccca cacccuccaa      240

ccccaccacc acauccccgu aguccccgcc caacaacccg ucauccccca acaacccaug      300

augcccgucc ccggccaaca cucaaugacc cccauccaac accaccaacc caaccuccca      360

ccacccgccc aacaacccua ccaaccccaa cccguccaac cccaacccca ccaacccaug      420

caaccccaac cacccguaca ccccaugcaa ccccucccac cccaaccacc ccuaccuccc      480

auguucccca ugcaaccccu cccacccaug cuccccgacc ucacccucga agccuggccc      540

uccaccgaca aaaccaaacg cgaagaagua gacuaa                                576


<210>  1003
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  1003
augccccuac ccccccaccc aggccacccc ggcuacauaa acuucuccua cgaaguacuc       60

acaccccuaa aaugguacca auccauccga ccccccuacc ccucauacgg cuacgaaccc      120

augggcggcu gguaa                                                       135


<210>  1004
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  1004
augccccucc ccccccaccc cggccacccc ggcuacauaa acuucucaua cgaaguccuc       60

accccccuaa aaugguacca auccauccgc ccccccccca ugcuccccga ccucacacuc      120

gaagccuggc ccucaaccga caaaacaaaa cgcgaagaag ucgacuaa                   168


<210>  1005
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  1005
auggccguaa uggccccccg aacccucguc cuccuacucu caggagcccu cgcccucacc       60

caaaccuggg ccaugccccu cccaccccac ccaggccacc ccggauacau caacuucucc      120

uacgaaguac ucaccccccu aaaaugguac caauccaucc gcccccccua ccccucauac      180

ggcuacgaac ccaugggcgg augguaa                                          207


<210>  1006
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  1006
auggccguaa uggcaccccg cacccucguc cuacuccuau ccggcgcccu cgcccucaca       60

caaaccuggg ccaugccccu cccaccccac cccggccacc ccggcuacau aaacuucucc      120

uacgaagucc ucaccccacu caaaugguac caauccaucc gcccaccacc caugcuaccc      180

gaccucacac ucgaagccug gcccuccacc gacaaaacaa aacgcgaaga agucgacuaa      240


<210>  1007
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  1007
augggcaccu ggauccucuu cgccugccua gucggcgccg ccuucgccau gccccuccca       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg aaguccuaac accccuaaaa      120

ugguaccaau ccaugauccg cccacccuac uccuccuacg gcuacgaacc caugggcgga      180

uggcuccacc accaaaucau ccccgucguc ucccaacaac acccccucac ccacacccuc      240

caaucacacc accacauccc cguagucccc gcccaacaac cccgcguacg acaacaagcc      300

cucaugcccg uccccggcca acaauccaug acccccaccc aacaccacca acccaaccuc      360

ccacuccccg cacaacaacc cuuccaaccc caacccgucc aaccccaacc ccaccaacca      420

augcaacccc aaccacccgu ccaacccaug caaccccucu uaccccaacc accccuacca      480

cccauguucc cccuccgccc ccuaccaccc auccuccccg accuccaccu cgaagccugg      540

cccgccaccg acaaaacaaa acaagaagaa gucgacuaa                             579


<210>  1008
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  1008
augccccuac caccccaccc aggccacccc ggcuacauca acuucucaua cgaaguccuc       60

accccccuaa aaugguacca aucaaugauc cgccccccau acucauccua cggcuacgaa      120

cccaugggcg gcugguaa                                                    138


<210>  1009
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  1009
augccccucc ccccccaccc aggccacccc ggcuacauca acuucuccua cgaaguacuc       60

accccccuaa aaugguacca auccaugauc cgcccccccc ccauacuccc cgaccuccac      120

cucgaagccu ggcccgccac agacaaaacc aaacaagaag aaguagacua a               171


<210>  1010
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  1010
auggcaguca uggcaccccg cacccucguc cuccuccucu ccggcgcccu cgcccuaacc       60

caaaccuggg caaugccacu acccccacac cccggccacc ccggcuacau caacuucuca      120

uacgaagucc uaacaccccu caaaugguac caaucaauga uccgcccacc cuacuccucc      180

uacggcuacg aacccauggg cggcugguaa                                       210


<210>  1011
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  1011
auggccguca uggcaccccg aacacucguc cuccuccucu ccggcgcccu cgcccucaca       60

caaacauggg ccaugccccu cccaccccac cccggccacc ccggcuacau caacuucucc      120

uacgaagucc ucacaccccu aaaaugguac caauccauga uccgcccacc cccaauacuc      180

cccgaccuac accucgaagc cuggcccgcc accgacaaaa ccaaacaaga agaagucgac      240

uaa                                                                    243


<210>  1012
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  1012
augggcaccu ggauacucuu cgccugccuc cucggcgccg ccuucuccau gccccuacca       60

ccccaccccg gacaccccgg cuacaucaac uucuccuacg aaguccuaac accccucaaa      120

ugguaccaaa auaugauacg ccaccccuac acauccuacg gcuacgaacc caugggcgga      180

uggcuccacc accaaaucau ccccgucguc ucacaacaaa ccccacaauc ccacgcccuc      240

caaccccacc accacauccc cauggucccc gcccaacaac ccggcauccc ccaacaaccc      300

augaugcccc uccccggcca acacuccaug acccccaccc aacaccacca acccaaccua      360

ccccuacccg cccaacaacc cuuccaaccc caacccguac aaccccaacc ccaccaaccc      420

cuucaacccc aaucucccau gcaccccauc caaccccucc ucccccaacc accccuucca      480

cccauguucu caaugcaauc acuccucccc gaccuccccc ucgaagccug gcccgccacc      540

gacaaaacca aacgagaaga agucgacuaa                                       570


<210>  1013
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  1013
augccccuac caccccaccc cggccacccc ggcuacauca acuucuccua cgaaguccua       60

acaccccuaa aaugguacca aaacaugauc cgccacccau acaccucaua cggcuacgaa      120

ccaaugggcg gcugguaa                                                    138


<210>  1014
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  1014
augccccucc caccccaccc cggccacccc ggcuacauca acuucuccua cgaaguccua       60

acaccccuca aaugguacca aaacaugauc cgacaccccu cccuacuccc cgaccucccc      120

cuagaagcau ggcccgccac cgacaaaacc aaacgcgaag aagucgacua a               171


<210>  1015
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  1015
auggccguca uggcaccccg cacccuaguc cuccuccucu caggcgcccu cgcacucacc       60

caaacauggg ccaugccccu acccccacac cccggccacc caggcuacau caacuucuca      120

uacgaagucc ucaccccacu aaaaugguac caaaacauga uacgccaccc cuacaccuca      180

uacggauacg aacccauggg cggcugguaa                                       210


<210>  1016
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  1016
auggccguca uggcaccccg cacucucguc cuccuacucu ccggcgcccu agcccucacc       60

caaaccuggg ccaugccccu acccccacac cccggccacc ccggcuacau caacuucuca      120

uacgaagucc ucaccccacu aaaaugguac caaaacauga uccgccaucc cucacuccuc      180

cccgaccucc cccuagaagc cuggcccgcc acagacaaaa ccaaacgcga agaagucgac      240

uaa                                                                    243


<210>  1017
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  1017
augggcaccu ggauacucuu cgccugccuc cucggcgcag ccuucuccau gccccuccca       60

ccccaccccg gccaccccgg cuacaucaac uucucuuaca uccgccaccc cuacaccucc      120

uacggcuacg aacccauggg cggcuggcua caccaccaaa ucauccccgu cguaucccaa      180

caaaccccac aaucacacgc ucuccaaccc caccaccaca uccccauggu ccccgcccaa      240

caacccggca ucccccaaca acccaugaug ccccuccccg gccaacacuc caugaccccc      300

acccaacacc accaacccaa ccucccccuc ccagcccaac aacccuucca accccaaccc      360

guccaacccc aaccacacca accacuacaa ccacaauccc ccaugcaccc cauccaacca      420

cuccuccccc aaccaccccu cccacccaug uucucaaugc aaucccuccu acccgaccuu      480

ccccuugaag ccuggcccgc caccgacaaa accaaacgag aagaagucga cuaa            534


<210>  1018
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  1018
augggcaccu ggaucuucuu cgcaugccuc cuaggcgccu cccucgccau gccccuccca       60

ccccaccccg gacaccccgg cuacaucaac uucuccuacg aaguccucac cccacuaaaa      120

ugguaccaaa acaugauccg ccaccccuac accuccuacg gauacgaacc caugggaggc      180

uggcuccacc accaaaucau ccccgucguc ucacaacaaa caccccaauc ccacgcacuc      240

caaccccacc accacauccc cauggucccc gcccaacaac ccggaauccc ccaacaaccc      300

augaugcccc uccccggaca acacuccaug acccccaccc aacaccacca accaaaccuc      360

ccccuccccg cccaacaacc cuuccaacca caacccgucc aaccccaacc ccaccaacca      420

cuccaacccc aaucccccau gcaccccauc caaccacucc ucccccaacc accccuccca      480

cccauguucu caaugcaauc ccuccuuccc gaccuccccc ucgaagccug gcccgccacc      540

gacaaaacca aacgcgaaga aguagauuaa                                       570


<210>  1019
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  1019
augggcaccu ggauacucuu cgccugccua cucggcgccg cauucucaau gccccucccc       60

ccccaccccg gccaccccgg cuacauaaac uucuccuacg aaguccucac cccccucaaa      120

ugguaccaaa acaugauuag acacccaucc cuccuccccg accucccccu cgaagcaugg      180

cccgcaaccg acaaaaccaa acgcgaagaa gucgacuaa                             219


<210>  1020
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  1020
augggcacau ggauccucuu cgccugccua cucggagccg cuuuuuccau gccccucccu       60

ccccaccccg gccaccccgg cuacauaaac uucuccuacg aagaccucua ccucgaagcc      120

auccgcaucg accgcaccgc cuucguccuc acaccccuua aaugguacca aaacaugauc      180

cgccaccccu acaccuccua cggcuacgaa cccaugggcg guuggcucca ccaccaaauc      240

auccccguag ucucacaaca aaccccacaa ucccacgccc uccaacccca ccaccacaua      300

ccaauggucc ccgcccaaca accaggcauc ccccaacaac ccaugaugcc ccuccccggc      360

caacacucca ugaccccaac ccaacaccac caacccaacc ucccccuccc cgcccaacaa      420

cccuuccaac cccaacccgu ccaaccccaa ccccaccaac cccuccaacc ccaauccccc      480

augcacccca uccaaccucu ccucccccaa cccccacucc caccaauguu cucaaugcaa      540

ucacuccucc ccgacuuacc ccuagaagcc uggcccgcca ccgacaaaac caaacgagaa      600

gaaguagacu aa                                                          612


<210>  1021
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  1021
augggcaccu ggauccucuu cgccugccuc cucggcgccg ccuucuccau gccccuccca       60

ccccaccccg gccaccccgg cuacaucaac uucucauaug aaguccucac accccucaaa      120

ugguaccaaa acaugauccg ccaccccaca ccccaauccc acgcccucca accacaccac      180

cacaucccca ugguccccgc ccaacaacca ggcaucccac aacaacccau gaugccccua      240

ccaggccaac acuccaugac ccccacccaa caccaccaac ccaaccuacc ccuccccgca      300

caacaacccu uccaaccaca acccguccaa ccccaacccc accaaccccu acaaccccaa      360

ucccccaugc acccaaucca accccuccuc ccccaaccac cccucccacc cauguucucc      420

augcaaucac uccuccccga ccucccccua gaagccuggc ccgcaaccga caaaaccaaa      480

cgcgaagaag ucgacuaa                                                    498


<210>  1022
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  1022
augccccucc caccccaccc cggccacccc ggcuacauca acuucuccua cgaaguacuc       60

accccucuca aaugguacca aaacaugauc cgacaccccu acaccuccua cggcuacgaa      120

cccaugggcg gcuggcucca ccaccaaauc auccccgucg ucucccaaca aacaccccaa      180

ucccacgcac uacaacccca ccaccacauc cccauggucc ccgcccaaca acccggcauc      240

ccccaacaac ccaugaugcc acuccccggc caacacucca ugacccccac ccaacaccac      300

caacccaacc ucccccuacc cgcccaacaa cccuuccaac cccaacccgu ccaaccacaa      360

ccucaccaac cacuccaacc ccaaucaccc augcacccca uccaaccacu ccuaccccaa      420

cccccacucc cacccauguu cuccaugcaa ucacuccucc ccgaccuccc ccuagaagcc      480

uggcccgcca ccgacaaaac caaacgcgaa gaagucgacu aa                         522


<210>  1023
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  1023
augccaggag ucgcccggcu accccuacuc cuaggacucc uccuacuacc acgcccugga       60

cgaccccuag accuggccga cuacacguac gaccuagccg aagaagacga cuccgaaccc      120

cucaacuaca aagaccccug caaggccgcc gccuuccuag gcgacauagc ccuagacgaa      180

gaagaccucc gagccuucca aguccaacaa gcggucgacc ugcgccgaca cacggccagg      240

aaaucaucca uaaaagccgc uguaccggga aacacaucaa cccccucaug ccaaucgaca      300

aacggacaac cacaaagggg cgcaugcgga agauggcgcg ggcgaucacg cucacgccgc      360

gcagccacaa gccgcccgga gcgagugugg cccgacgggg uaauacccuu cgucauaggg      420

ggaaacuuca cuggaucaca acgggcaguc uuuagacaag caaugagaca cugggaaaag      480

cauaccugcg ucacauuccu agaacggacc gacgaagauu cauacaucgu auucaccuac      540

cgcccaugcg gauguugcuc auacguaggc cgaagaggcg gcggccccca agcgauaucg      600

auaggcaaga acugcgacaa auucgggaua guuguacacg aacuaggaca cgucguaggc      660

uucuggcacg aacacaccag acccgaccgg gaccggcacg uauccauagu ccgcgaaaac      720

auccaacccg gacaagaaua caacuuccua aaaauggaac cacaagaagu cgaaucgcua      780

ggcgaaaccu augacuucga uuccaucaug cacuaugcuc gcaacaccuu cucacgaggc      840

aucuuccucg acaccaucgu ccccaaauac gaaguuaacg gagucaaacc acccauagga      900

caacgcacgc gacucucaaa aggcgauauc gcucaagcac gcaaacucua caaguguccc      960

gccugcggcg aaacgcucca ggacucgaca ggcaacuucu caucccccga auacccgaac     1020

ggauacagcg cacacaugca cugugucugg cgaaucucag uaacaccagg cgagaaaauc     1080

auccuuaacu ucacaucccu cgaccuguac agaucccgcc ucugcuggua cgauuacguc     1140

gaagucagag acggguucug gcgaaaagca ccgcuccgag gccgauucug uggauccaaa     1200

cugccagaac ccauagucuc cacagacucu cgacucuggg uugaguucag aagcucuagu     1260

aacugggucg gcaaaggcuu cuucgccguc uacgaagcaa ucugcggagg agacguaaag     1320

aaagauuacg gccacauaca gucccccaac uaccccgacg acuaccggcc caguaaagua     1380

uguaucugga gaauccaggu aagcgaaggc uuccauguug ggcucaccuu ucagagcuuc     1440

gaaauagaac gccacgacuc augcgcuuau gacuaucucg aaguacgcga cggccacucc     1500

gaaucaagca cacucauagg cagauacugc ggauacgaaa aacccgauga caucaaaucc     1560

acguccagcc gccuauggcu caaauucguc ucagauggaa gcauaaacaa agccggauuu     1620

gcuguuaacu ucuucaagga aguagacgag ugcucccgac ccaaccgcgg cgggugcgaa     1680

caacgcugcc ucaacacacu cgguuccuac aaaugcagcu gcgacccagg cuacgaacua     1740

gccccugaua agcgucgcug cgaagcagcc ugcggugggu uccucacaaa acuaaacgga     1800

uccauaacaa gcccuggcug gccaaaagaa uaucccccua acaagaacug caucuggcaa     1860

cugguggcgc ccacacaaua ccgaauaagc cuacaauuug acuucuucga gacagaagga     1920

aaugacgugu gcaaguacga cuucguagaa guccgcuccg gguuaaccgc cgacuccaag     1980

cugcauggga aauucugcgg auccgaaaaa ccagaaguga uuacgagcca auacaacaac     2040

augcgagucg aguucaaguc agacaacaca gucuccaaga aaggcuuuaa agcucacuuc     2100

uucucagaca aagacgagug cucaaaagac aauggagggu gucaacaaga cugcguuaac     2160

acauucgggu ccuacgaaug ccaaugccgc ucuggguucg uacuucacga uaacaagcac     2220

gacugcaaag aagccggaug cgaccacaag gugacaagca ccuccggcac cauaacgucc     2280

cccaacuggc cagauaaaua ccccucaaag aaagaaugca cgugggccau caguagcacu     2340

cccggccaca gagucaaacu cacauucaug gaaauggaca ucgaaagcca gccggagugc     2400

gcguacgacc accucgaagu guucgacgga cgcgacgcga aggcuccagu gcucggccga     2460

uucugcggau ccaagaagcc agaaccaguc uuagcaacug gaagccgaau guuccuacga     2520

uucuacuccg acaauuccgu ucaacgaaaa ggcuuccaag ccucccacgc caccgaaugc     2580

ggcggacaag uccgagcgga cguaaaaacc aaagaccucu acagccacgc gcaauucggg     2640

gacaacaacu acccaggugg cguagacugc gaauggguaa uagucgcaga agaaggcuac     2700

ggagucgagc uaguauucca gaccuucgaa guugaagaag aaacagacug cggcuacgac     2760

uacauggaac uauucgacgg uuacgacucc accgcacccc ggcucggacg guacugcggc     2820

uccggcccac cagaagaagu auacucagca ggagacagcg uccucgucaa auuccacucc     2880

gaugauacca uaacaaagaa aggguuucac cuacgcuaca cgagcaccaa auuccaagac     2940

acucuacaca gccgcaaaua a                                               2961


<210>  1024
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  1024
augguagccg gcacccgaug ccuacucgcc cuccuucucc cccaaguccu ccuaggcggc       60

gccgccggcc uggucccaga acuaggccgc cgcaaauucg cagccgcauc cuccggacgc      120

ccaucaucac agcccuccga cgaaguccuc uccgaguucg aacucagacu acuaucgaug      180

uucggccuua aacaacgccc caccccaucc cgugacgccg uagucccacc auacaugcuc      240

gaccuauacc gccgccacuc cgggcaaccc ggaucaccag cacccgacca ccgccucgaa      300

cgcgccgcau cccgcgccaa cacaguccgc uccuuccacc acgaagaauc ccucgaagaa      360

cuccccgaaa caucaggcaa aacaacccgc cgauucuucu ucaaccucuc cuccauaccc      420

acagaagagu ucaucaccuc cgcagaauua caagucuucc gcgaacaaau gcaagacgca      480

cucggcaaca acuccuccuu ccaccacaga aucaacaucu acgaaaucau caaacccgca      540

accgccaaca gcaaauuccc aguaacccga cuccuugaca cacgacucgu caaccaaaac      600

gccuccagau gggaaucauu cgacgucaca ccagcaguca ugcgcuggac cgcccaaggc      660

cacgcaaacc auggauucgu gguagaaguc gcccaccuag aagaaaaaca aggagucucc      720

aaacgccacg uccgcaucuc acgcucccuc caccaagacg aacacucaug gucacaaauc      780

cgaccccucc uaguaacauu cggacacgac ggcaaaggcc acccccuaca uaaacgcgaa      840

aaacgacaag ccaaacauaa gcaacgaaaa cgccucaaau caagcuguaa acgucaucca      900

cucuacgucg acuucucuga cgucggcugg aacgacugga ucguagcacc acccggcuac      960

cacgccuuuu acugccacgg agaaugcccc uucccccucg ccgaccaccu aaauuccacc     1020

aaccacgcaa uaguccaaac ccuaguuaac uccgucaacu ccaaaauccc aaaagcaugc     1080

ugcguuccca cagaacucuc agcaaucucc augcucuacc uugacgaaaa cgaaaaaguc     1140

guccugaaaa acuaccaaga cauggucguc gaaggcugcg gcugccgaua a              1191


<210>  1025
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  1025
augauacccg gcaaccguau gcucaugguc guccuccucu gccaaguacu ccucggcgga       60

gccucacacg caucucucau acccgaaacu ggcaaaaaaa aagucgccga aauccaaggc      120

cacgcaggag gacgccgcuc aggucaaucc cacgaacucc uacgcgacuu cgaagccacc      180

cuacuacaaa uguucggccu ccgacgccga ccccagcccu ccaaauccgc cgucauaccc      240

gacuacaugc gcgaccucua ccgacuucaa uccggcgaag aagaagaaga acaaauacac      300

agcaccggcc ucgaauaccc cgaacgucca gccucccgcg ccaacaccgu ccgcucuuuc      360

caccacgaag aacaccucga aaacaucccc ggcacauccg aaaacuccgc cuuccgauuc      420

cucuucaacc uauccucaau ccccgaaaac gaagucauau ccuccgccga acuccgucuc      480

uuccgcgaac aaguagacca aggccccgau ugggaacgcg gcuuccaccg caucaauauc      540

uacgaaguca ugaaaccacc agccgaaguc guacccggac accucaucac acgcuuacua      600

gacacccgcc ucguccacca caacguaaca cgcugggaaa ccuucgacgu cuccccagcu      660

guucuccgau ggacacgcga aaaacaaccc aacuacggcc ucgccaucga agucacccac      720

cuccaccaaa cccgaaccca ccaaggccaa cacgucagaa ucucccgcuc ucucccccaa      780

ggcucaggca acugggccca acuacgcccc cuacuuguca ccuucggcca cgacggacga      840

ggccacgcac uaacgcgacg ccgccgcgcc aaacgcucac ccaaacacca cucucagcgc      900

gccagaaaaa aaaacaaaaa uugccgccga cacucacugu acgucgacuu cagcgacguc      960

ggcuggaaug acuggaucgu cgcccccccc ggcuaccaag cauucuacug ccacggcgac     1020

ugcccauucc cacuagcuga ccaccucaac ucgaccaacc acgcaauugu acaaacccuc     1080

gucaauuccg ucaacagcuc caucccaaaa gcaugcugcg ugcccaccga acucuccgcu     1140

aucuccaugc ucuaccucga cgaauacgac aaagucguac ucaaaaacua ccaagaaaug     1200

gucgucgaag gaugcggcug ccgcuaa                                         1227


<210>  1026
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  1026
augcccgguc uaggccgccg cgcacagugg cucugcuggu gguggggacu acucugcucc       60

ugcugcggcc cuccccccuu acguccaccc uuaccagcag ccgccgccgc ggcagcagga      120

ggccaacuac ucggcgacgg uggcuccccc ggacgaacgg aacaaccccc ccccucaccc      180

caauccucaa gcggcuuccu cuaccgccgc cucaaaaccc aagaaaaacg agaaaugcaa      240

aaagaaauac uauccguccu aggccuucca caccggcccc gcccacucca cggccugcaa      300

caaccccagc cacccgcccu ccgccaacaa gaagaacaac aacaacaaca acaacucccc      360

cggggugaac ccccuccagg ccgccuaaaa ucugccccuc ucuucaugcu cgaccucuac      420

aaugcccuau ccgccgauaa cgacgaagau ggagcgucag aaggagaacg ccaacaauca      480

uggccccacg aagccgccuc cucaucccaa cgccgacaac ccccgcccgg cgccgcccac      540

ccccuaaacc guaaaucccu gcucgccccc ggcucaggca gcgguggugc auccccacuc      600

accucggccc aagacuccgc auuccuaaac gacgcagaca uggucaugag cuucgucaac      660

cuagucgaau acgacaaaga auucucccca cgccaacgac accauaaaga auucaaauuc      720

aaccucucac agauacccga aggagaaguc gucaccgccg cagaauuccg aaucuacaaa      780

gacugcguaa uggguagcuu caaaaaccaa acauuccuaa ucucuauaua ccaaguacuc      840

caagaacacc aacaccguga cagugaccua uuccuccucg acacccgagu cguuugggcc      900

ucagaagaag gcuggcucga auucgacauc acagcaacca gcaaccuaug gguaguaaca      960

ccgcaacaca acaugggccu acaacuaucc guagucaccc gagacggagu acacguucac     1020

ccgcgcgcag ccggccucgu aggacgcgac ggccccuacg acaaacagcc cuucaugguc     1080

gccuucuuca aagucuccga aguacacguc cgcaccaccc gcuccgccuc cucucgacgc     1140

cgccaacaau cccgaaaccg auccacccaa ucccaagacg ucgcccgcgu uuccucugcc     1200

ucagacuaca auuccucaga acucaaaacc gccugccgaa aacacgaacu auauguauca     1260

uuccaagacc uuggcuggca agacuggauc aucgccccca aaggcuacgc agccaacuac     1320

ugcgacggcg aaugcuccuu cccacuaaac gcccacauga acgccaccaa ccacgccauc     1380

guccaaacac ucgugcaccu uaugaacccc gaauacguac ccaaaccaug cugcgccccc     1440

accaaacuaa acgccaucuc cguacucuac uucgaugaca acuccaacgu cauacuaaaa     1500

aaauaccgua acaugguagu acgcgccugc gguugccacu ga                        1542


<210>  1027
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  1027
augcacgugc guucacuacg agcagccgcc ccacacucau ucgucgcccu cugggcuccc       60

cuuuuucucc uacgcucugc ccucgccgac uucucccuag acaacgaagu acacagcuca      120

uucauccacc gccgucuccg cucucaagaa agacgcgaaa ugcaacguga aauccucucc      180

auccucggcc ucccccaccg accccgcccc caccuacaag gcaaacacaa cuccgccccc      240

auguucaugc ucgaccucua caacgccaug gccguagaag aaggaggagg acccgguggc      300

caaggcuucu ccuaccccua caaagccguc uuuuccaccc aagguccccc gcucgcauca      360

cuccaagacu cccacuuccu caccgacgcc gacaugguca ugucauucgu caaccuuguc      420

gaacacgaca aagaguucuu ccacccccgc uaccaccauc gcgaguuccg cuucgaccuc      480

agcaaaauuc ccgaaggcga agccgucacc gccgccgagu uccgaaucua caaagacuac      540

auccgugaac gcuucgacaa cgaaacuuuc cgcaucucag ucuaccaagu ccuccaagaa      600

caccuaggcc gcgaaucaga ccucuuucuc cucgacucac gaacccucug ggccucagaa      660

gaaggauggc ucgucuucga caucacagcc acauccaacc acugggucgu caacccucgc      720

cacaaccuug gacuccaacu guccgucgaa acccucgacg gccaauccau aaaccccaaa      780

cucgccggcc ucauaggccg acacggaccc caaaacaaac aaccauucau ggucgcauuu      840

uucaaagcaa ccgaagucca cuuuagaucc auccguucca ccggaucaaa acaacgcucc      900

caaaaccgcu ccaaaacccc caaaaaccaa gaagcccucc gcauggccaa cguagcagaa      960

aacuccucca gcgaccaacg ccaagccugc aaaaagcacg aacucuacgu aucauuucga     1020

gaccucggcu ggcaagacug gauaaucgcc ccagaaggcu acgccgcaua cuacugcgaa     1080

ggagaaugcg ccuucccccu aaauuccuac augaacgcca ccaaccacgc caucguccaa     1140

acccucgucc acuucaucaa ccccgaaacu gucccaaaac ccugcugcgc ccccacacaa     1200

cuaaacgcca ucucaguccu cuacuuugac gacucaucua acguaauccu aaagaaauau     1260

cgcaacaugg uaguccgcgc cugcgguugc cacuag                               1296


<210>  1028
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  1028
augaaagccu ccgccgcccu ccuaugccuc cuccucaccg ccgccgcauu cuccccccaa       60

ggccucgccc aaccagucgg cauaaacacc uccaccaccu gcugcuaccg auucaucaac      120

aaaaaaaucc caaaacaacg acucgaaucc uaccgccgca ccaccuccuc ccacugcccc      180

cgagaagccg ucaucuucaa aaccaaacuc gacaaagaaa ucugcgccga cccaacccaa      240

aaaugggucc aagacuucau gaaacaccua gacaaaaaaa cccaaacccc aaaacucuaa      300


<210>  1029
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  1029
augcucuuaa cccuuaucau acuucuuccc gucgucagca aguucagcuu ugucucacuc       60

agugcacccc aacacuggag cugccccgaa ggaacacuug ccggcaacgg caauagcaca      120

ugcguugggc cggcucccuu ccuaauauuc agccacggaa acagcauauu ccgaaucgac      180

acagagggaa ccaacuacga acagcuggua gucgacgcug gcguaagcgu caucauggac      240

uuccacuaca acgagaagcg aaucuacugg guagaucucg aacgccaacu acugcaacgg      300

guauucuuga acggcucgcg acaggagcgc gucugcaaua ucgaaaagaa cgucucagga      360

auggcuauca acuggauuaa ugaagaggug auauggagca accaacagga gggaaucaua      420

accgucacag acaugaaggg uaacaacucc cacauccuuc ucagcgcgcu caaauacccu      480

gcaaaugucg ccguggaucc ugucgaacgu uuuauauucu ggucaaguga aguagccggc      540

ucccucuaca gagccgaccu cgacggugua ggggucaagg cacuacucga aacguccgag      600

aaaauaacag caguaucgcu ggacguacuc gacaaacgcc uauucuggau ucaguacaac      660

cgagaaggca gcaacuccuu aaucugcagu ugcgacuacg acggagguag cgugcauaua      720

aguaaacacc caacgcagca caaccuauuu gccaugucac uguucgggga ccgcaucuuc      780

uacagcaccu ggaaaaugaa aacaauaugg aucgcaaaca aacacaccgg caaggauaug      840

guccgcauca accuacacuc uucauucgua ccccuagggg agcucaaagu agugcacccu      900

cucgcccaac caaaagcaga ggaugauacc ugggaacccg aacaaaagcu gugcaaacuc      960

cgaaagggca acugcucgag caccgucugc ggacaagacc ugcaaagcca ccucugcaug     1020

ugugcggaag gauacgcacu cucacgagac cggaaguacu gcgaggacgu caacgaaugc     1080

gccuucugga accacggaug cacucuugga uguaagaaca ccccaggauc cuauuacugu     1140

accugcccag ucggauucgu acuacuacca gacggaaaac gaugccacca acugguaucc     1200

ugcccccgaa acguauccga augcucccac gauugcgucc uaaccucaga ggggccccuc     1260

ugcuucugcc cagagggauc cguguuagaa cgcgacggca agacuugcag cggcugcagc     1320

agcccagaca acggcgggug cagccaacua ugcguaccac uaucaccagu uucaugggaa     1380

ugcgacugcu ucccggguua cgaccuccag cucgacgaaa aaucaugugc ggccagcgga     1440

ccacagcccu uccuccuauu cgccaauuca caagacaucc ggcacaugca cuucgacggc     1500

accgacuacg guacccuacu gagccaacaa auggguaugg uguacgcgcu cgaccacgac     1560

ccaguagaaa acaaaauaua cuucgcccac acagcccuca aguggaucga acgagccaac     1620

auggauggau cacaacgcga gcggcuaaua gaggaaggug uggacgugcc agaaggccug     1680

gccguagacu ggauaggccg cagauucuau uggacagaca gagguaaauc acucaucgga     1740

cgaucagacc ucaacggcaa aagguccaaa aucaucacua aagagaacau aucacaacca     1800

cgcggcauag ccguccaccc cauggccaaa cgccucuucu ggaccgacac gggcaucaac     1860

ccaagaauag aguccagcag ccuccagggc cuaggaagac uuguaaucgc aucguccgau     1920

cucauuuggc ccagcgggau cacaaucgau uuccuaacug acaaacucua cuggugcgac     1980

gccaaacaaa guguaaucga aauggcaaac cucgacggau cgaaacgacg gcgccucacc     2040

caaaacgaug uuggccaucc cuucgcagua gcagucuuug aggacuacgu cugguucagc     2100

gacugggcca ugcccuccgu aaugcggguu aacaaacgca ccggcaaaga ccgaguccga     2160

cuacaggguu ccaugcuuaa accgagcucc cuaguuguag uacacccacu agcaaaaccc     2220

ggggccgacc ccugcuuaua ucaaaacgga ggaugcgaac acaucugcaa gaaacgccuc     2280

ggcaccgcau gguguagcug ccgagaagga uuuaugaaag ccuccgacgg caaaaccugu     2340

cuggcccuag auggccacca acuccuugcg ggcggcgaag uagaccuuaa aaaccaagug     2400

accccgcuag acauacucuc aaaaacgcgc gucucagaag acaacaucac agaaagccaa     2460

cacaugcucg uagcagaaau caugguaagc gaccaagacg acugcgcacc cguaggaugc     2520

agcauguaug cacggugcau aagcgaagga gaagacgcga ccugccaaug ccuaaaagga     2580

uucgccggag acgguaagcu cugcucagau auugacgaau gcgaaauggg aguacccgug     2640

uguccacccg ccagcucaaa gugcaucaac acugaaggag gcuacgucug cagaugcagc     2700

gagggcuauc aaggcgacgg cauccauugc cuagauauag acgagugcca gcuaggcgag     2760

cacucgugcg gcgagaacgc gucgugcaca aacacggaag guggcuauac augcaugugc     2820

gccggaagac ucagcgaacc gggucuaauu ugccccgaca gcaccccacc uccacaccuu     2880

cgcgaagacg accaccacua cuccguccgc aacucggacu cagaaugccc ccucagucau     2940

gauggcuacu gcuugcauga cggcguuugu auguauaucg aagcccuaga caaguacgca     3000

ugcaacugcg ucguagguua caucggagag cgcugccaau aucgcgaccu aaaauggugg     3060

gaacucagac acgcagguca cggucagcaa caaaagguua ucgucguagc cguuuguguc     3120

gugguccuag ucaugcuccu ucuccuaucg cucuggggcg cccacuacua cagaacccaa     3180

aaacuccuau ccaaaaaccc gaaaaauccc uacgaagaau cgaguaggga cguacguucg     3240

cgacgacccg cagacacgga agacggcaug aguucgugcc cccaaccaug guucguaguu     3300

auuaaggaac aucaagauuu gaaaaacggc ggacagccag ucgccggaga ggacggccaa     3360

gcagcagaug gauccaugca acccacauca uggagacaag aaccccaacu augcggaaug     3420

ggaacggaac aaggcugcug gauuccaguc aguuccgaca aaggcucaug cccacaagua     3480

auggaacgau cguuccacau gccauccuac ggaacccaaa cacucgaagg cgguguagaa     3540

aagccacaca gccuccucuc ggcaaacccc cuauggcagc agcgcgcacu agacccuccc     3600

caucaaaugg agcugaccca auag                                            3624


<210>  1030
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  1030
augaccgccg gcagacgcau ggaaaugcua ugcgccggcc gaguccccgc acuccuacuc       60

ugccucggcu uccaccuccu acaagccguc cuauccacca cagucauccc aucaugcauc      120

ccaggcgaaa gcucugacaa cugcaccgcc cuaguccaaa ccgaagacaa cccccgcguc      180

gcccaagucu ccaucacaaa augcucaucc gacaugaacg gcuacugccu acacggccaa      240

ugcaucuacc ucgucgacau gucccaaaac uacugcagau gcgaagucgg cuacaccgga      300

guccgcugcg aacacuucuu ccucacagua caccaaccuc ucuccaaaga auacgucgcc      360

cucaccguca uacucauuau ccucuuccuc aucaccguag ucggcuccac auacuacuuc      420

ugccgcuggu accgcaaccg caaauccaaa gaacccaaaa aagaauacga acgcgucacc      480

uccggcgacc ccgaacuccc ccaaguauaa                                       510


<210>  1031
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  1031
auggccgaag gcgaaaucac aaccuucacc gcccucaccg aaaaauucaa ccuccccccc       60

ggcaacuaca aaaaacccaa acuccuauac ugcuccaacg gcggacacuu ccuccguaua      120

cuccccgacg gcacagucga cggcacccga gaccgcucug accaacacau ccaacuccaa      180

cucucagccg aaucagucgg cgaagucuac auaaaaucca ccgaaacagg ccaauaucuc      240

gcaauggaca ccgacggccu ucucuacggc ucccaaaccc ccaacgaaga augccucuuc      300

cucgaacgcc uagaagaaaa ccacuacaac acauacaucu ccaaaaaaca cgcagaaaaa      360

aacugguucg uaggccucaa aaaaaacggc uccugcaaac gcggcccccg cacccacuac      420

ggccaaaaag ccauccucuu ccucccccua cccgucucau ccgacuaa                   468


<210>  1032
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  1032
augguagggg uaggaggagg ggauguagaa gaugugacgc caaggccagg agggugucaa       60

auaagcggaa gaggggcaag aggcuguaac gggauaccgg gggcagcggc gugggaggca      120

gcgcugccga gaagacgacc acgaaggcau ccgaguguga acccgcgguc aagagcggca      180

gggagcccga gaacgagagg gagaagaaca gaggaaaggc caaguggaag uagauuaggg      240

gauaggggaa gagggagggc gcuaccggga gggagauugg gagggcgagg gagagggaga      300

gcgccagaga ggguaggagg gcgggggcgg gggaggggga cagcggcgcc gagagcggca      360

ccagcagcga gagggagcag gccagggccg gcggggacga uggcggcggg aagcauaaca      420

acacugccgg cguuaccgga ggacggaggg aguggggcgu ucccgccagg gcacuuuaaa      480

gauccaaaga gguuguauug caaaaacgga ggguucuuuc ugaggauaca uccagauggg      540

agaguagaug gaguaaggga gaaaucggac ccacacauaa aacugcaauu gcaagcagaa      600

gagagagggg uagugagcau aaaaggggug ugugcaaaca gauaccuagc gaugaaggaa      660

gauggaagac uguuagcguc gaaaugugua acggacgagu gcuuuuucuu ugaaaggcuc      720

gagagcaaua acuauaacac auacaggagc aggaaguaua caucauggua uguagcacuc      780

aagagaacgg gacaauacaa gcuagggagc aagacggggc cggggcaaaa ggcaauacua      840

uuucuaccga ugucggcaaa gagcuag                                          867


<210>  1033
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  1033
augcacaaau ggauccucac cuggauccua cccacccucc uguaccgcag cugcuuccac       60

aucaucugcc ucgucggaac cauaucccuc gccugcaacg acaugacccc cgaacaaaug      120

gccacaaacg uaaacugcag cucccccgaa cgccacaccc gcuccuacga cuacauggaa      180

ggcggagaca uccgcguacg ccgccuauuc ugcagaaccc aaugguaccu acgcauagac      240

aaaagaggca aagucaaagg cacacaagaa augaaaaaca acuacaacau cauggaaauc      300

cgcaccgucg cagucggaau cguagccauc aaaggagucg aaagcgaauu cuaccuagcc      360

augaacaaag aaggcaaacu auacgccaaa aaagaaugca acgaagacug caacuucaaa      420

gaacuaaucc ucgaaaacca cuacaacacc uacgccuccg ccaaauggac ccacaacggc      480

ggcgaaaugu ucguagcccu caaccaaaaa ggaauacccg uccgcggaaa aaaaaccaaa      540

aaagaacaaa aaaccgccca cuuccucccc auggccauca ccuaa                      585


<210>  1034
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  1034
augaaacucc uccccuccgu cguccucaaa cucuuccuag ccgcaguccu cuccgcacuc       60

gucaccggcg aaucccucga acgacuccga cgcggccugg ccgcaggcac cuccaacccc      120

gacccaccaa ccgucucaac agaccaacua cuaccccucg gcggaggccg cgacagaaaa      180

guccgcgacc uucaagaagc agaccucgac cuccuccgag ucacccucuc cagcaaaccc      240

caagcccucg ccacacccaa caaagaagaa cacggaaaac gcaagaaaaa aggcaaaggc      300

cucggcaaaa aacgcgaccc cugccuacgc aaauacaaag acuucugcau ccacggggaa      360

ugcaaauacg ucaaagaacu acgcgccccc ucaugcauau gccaccccgg cuaccacggc      420

gaacgcugcc acggccucuc ccuccccgua gaaaaccgac ucuacaccua cgaccacacc      480

accauccucg ccgucgucgc cgucguccuc uccuccguau gccuacucgu caucguaggc      540

cuccuaaugu uccgcuacca ccgccgaggc ggcuacgacg ucgaaaacga agaaaaaguc      600

aaacucggaa ugaccaacuc ccacuaa                                          627


<210>  1035
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  1035
auguggguca cgaaacuccu cccagcacua cuacuacaac acguccuauu acaccuccuc       60

cuccuaccca uagcaauacc cuacgcggaa gggcagcgaa aaagacgcaa cacgauccac      120

gaguucaaga aguccgcaaa aacaacccua aucaaaauag accccgcccu caaaaucaaa      180

accaagaaag ucaauaccgc agaccaaugc gcaaaccgcu gcacacgcaa caaaggccuc      240

ccauuuaccu gcaaagccuu cguuuuugac aaagccagaa agcaaugccu uugguuccca      300

uucaacagca ugagcuccgg cgucaagaaa gaguucggac acgaguucga ccuguacgaa      360

aacaaagacu acauccgaaa cugcauaauc ggcaaaggcc gcagcuacaa aggaacaguc      420

uccauaacca aaucaggcau caaaugccag ccuuggagcu ccaugauacc ccacgaacac      480

ucauuccucc cgucaagcua ccgagggaaa gaccuacaag aaaauuacug ccgaaaccca      540

cgcggggaag aaggcggacc cuggugcuuc accucaaacc cagaaguccg cuacgaagua      600

ugcgacaucc cccaaugcuc agaaguugaa ugcaugaccu gcaauggaga aagcuacaga      660

gggcucaugg accacaccga aagcggcaaa auaugccaac gaugggacca ccaaacacca      720

caccgacaca aauuccuccc cgaacgauac ccggacaaag gguucgauga caacuacugc      780

cguaaccccg acggccagcc acgcccaugg ugcuacacac uagacccaca cacucgcugg      840

gaauacugug caaucaaaac augcgccgac aauaccauga acgacacaga cgucccccug      900

gaaacaaccg aaugcaucca aggccaaggu gaaggcuacc gcggcacggu caauaccaua      960

uggaacggca uacccugcca acgaugggac agccaauacc cgcacgaaca cgacaugaca     1020

ccagaaaacu ucaaaugcaa agaccuucgg gaaaacuacu gccgaaaccc cgacggaucc     1080

gaaagccccu ggugcuucac aaccgacccc aacauccgcg uaggauacug uucacaaauc     1140

ccaaacugug acaugagcca cggacaggac ugcuacagag guaacggcaa aaacuacaug     1200

ggcaaccucu cccaaacacg auccggacug accugcagca ugugggacaa gaacauggaa     1260

gaucuccaua gacacaucuu cugggaacca gacgcaagca aauuaaacga aaacuacugc     1320

cgaaaccccg acgacgacgc ccacggcccc uggugcuaca caggaaaccc ucugauuccc     1380

ugggauuauu gucccaucuc ccgcugcgag ggcgacacca cccccacaau cgugaaccua     1440

gaccaccccg uaauaucaug cgcaaaaacg aaacagcucc gaguugugaa cggcauacca     1500

acuagaacua acaucggcug gauggucuca cuacgauacc guaacaaaca caucugcgga     1560

gguucgcuaa uaaaagaaag cuggguccuc accgcacgcc aaugcuuccc cagccgggau     1620

cugaaagacu acgaagccug gcugggaaua cacgacgucc acgguagagg agacgaaaaa     1680

ugcaaacagg uccucaacgu aucccaacuc guauacggcc cggagggcag ugaccucgua     1740

cucaugaaac uagcccgacc cgccguccuu gacgacuucg uauccaccau agaccucccc     1800

aacuacggcu gcaccauccc agaaaagacc agcugcagcg ucuacggaug gggauacacc     1860

ggccuaauaa auuacgacgg gcuacuccgc gucgcccacc uguacaucau gggcaacgaa     1920

aaaugcuccc agcaccacag aggcaaagua acccuaaaug aaagcgaaau augcgcaggg     1980

gccgagaaaa ucggcagugg cccaugcgaa ggcgacuacg ggggcccccu aguaugcgaa     2040

caacauaaaa ugcgcauggu ccucggagug aucguccccg gacgaggcug cgcgauccca     2100

aaucgcccag gcaucuucgu ccgcguggcu uacuacgcca aauggauaca caaaauaaua     2160

cuaaccuaca aaguacccca aagcuga                                         2187


<210>  1036
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  1036
auggcuaaag cggcggcaau cggaauagac cucggaacca ccuacucaug cgugggcguu       60

uuucagcacg gcaaaguaga aauaauagca aacgaucaag gaaacaggac aacucccucg      120

uacguggcau uuacagacac agagagacug auuggggacg ccgccaaaaa ccaagucgca      180

cugaaccccc agaacacagu uuucgacgcg aaaaggcuca uaggacgaaa auucggagac      240

ccaguggucc aaagugacau gaagcacugg ccauuccaag ugauaaauga cggcgacaaa      300

cccaagguac aagucucgua caaaggcgaa accaaggcau ucuacccaga agagauaucg      360

uccauggucc ucacaaagau gaaagaaaua gccgaagccu accucgggua cccagucaca      420

aacgcgguca uaaccguacc cgcguacuuc aacgacagcc aacgacaagc gacaaaagac      480

gccggaguca uagcaggccu caacguacug cgcauaauca acgaaccgac cgcggcagcc      540

auagccuacg ggcuagaccg cacaggaaaa ggggagcgca acgucuuaau cuucgaccua      600

ggcggaggca cauucgacgu cucaauacua accauagacg acggcaucuu cgaaguaaaa      660

gccacagccg gggacacgca ccuaggcggc gaagacuucg auaaccgccu aguaaaccac      720

uucguagaag aguucaagag aaagcacaag aaagacauaa gccaaaacaa acgggccgug      780

cgcaggcuaa ggaccgcaug cgaacgcgca aaacgaaccc ucagcucaag uacccaagca      840

agccuggaaa ucgacagucu cuucgaagga auagacuucu acaccuccau cacccgagcg      900

cgauucgaag aacuaugcag cgaccuauuc cgcucgacac uggaaccggu ggaaaaagca      960

cucagagacg cgaagcuaga caaagcccaa auccacgacc uaguauuggu gggaggcagu     1020

acaagaaucc caaaaguaca aaagcuccua caagauuucu ucaacggaag ggaccucaac     1080

aaauccauca accccgacga agcaguggcc uacggggcag caguccaggc agccauacug     1140

augggagaca aaagcgaaaa cgugcaagac cuacuccucc uggacguagc cccacuaagc     1200

cuaggacucg aaacagccgg aggaguaaug acagcacuga uaaaaaggaa cagcaccauc     1260

cccacgaaac aaacccaaau cuucacaacg uacucagaca accaacccgg agugcuaaua     1320

caaguauacg aaggcgagcg cgcaaugacu aaagacaaca accuccuggg cagguucgag     1380

cuaucaggaa uaccaccggc accacgggga gucccgcaaa uagaagugac cuucgacaua     1440

gacgccaaug gcauacuaaa cguaaccgca accgacaaau cuaccgggaa agcaaacaag     1500

auaacgauca cgaacgauaa agggcgcuua agcaaggaag aaaucgaacg caugguccaa     1560

gaagcagaaa aauacaaagc cgaggacgaa guacaacgcg aaagagugag cgcgaaaaac     1620

gcacuagaau cauacgcguu caacaugaaa agcgcagucg aagacgaagg ccucaaaggg     1680

aaaauauccg aggccgauaa aaagaaagua cuagacaaau gccaagaagu cauaagcugg     1740

cuagacgcca acaccuuagc cgaaaaagac gaguucgaac acaaaaggaa agaacuggaa     1800

caaguaugca accccauuau auccggccua uaccaaggag cuggaggacc gggacccggc     1860

ggauucggag cccaaggccc caaaggagga agugggagcg ggcccacgau agaagaaguc     1920

gacuaa                                                                1926


<210>  1037
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  1037
auggcgaaag ccgcagccau cggaauagac cucggcacca ccuacucaug cgucggcgua       60

uuccaacacg ggaaaguaga gaucaucgca aacgaccaag gaaacaggac cacaccauca      120

uacguagccu ucacagacac cgagcgccua aucggagacg ccgccaagaa ccaaguugcg      180

cucaacccac aaaacacagu cuucgacgca aaacgacuga uaggccgaaa auucggcgac      240

ccaguggucc aauccgacau gaagcacugg ccauuccaag uaaucaauga cggagacaaa      300

cccaaaguac aggucagcua caaaggagaa acaaaggccu ucuacccaga agaaauaagc      360

ucaauggucc ugaccaaaau gaaagaaaua gcagaggcuu accucggcua ccccguaaca      420

aacgcgguca ucaccguacc cgcauacuuc aacgacagcc aacggcaagc cacgaaagac      480

gccggaguca uagcaggccu aaacguacuc cgcauuauaa acgaaccaac cgccgccgcc      540

aucgcauacg gacucgaccg aacaggcaag ggcgagagaa acguacugau cuucgaccuc      600

ggaggaggaa cauucgacgu caguauacuc acgaucgacg acggaauauu cgagguaaag      660

gcaacggcug gagacacaca ccuaggcgga gaagacuucg acaacaggcu ugucaaccac      720

uucgucgaag aguucaaacg aaaacacaag aaagacauaa gccaaaacaa aagggccguc      780

cguagacuaa gaaccgccug cgaaagagcg aaaaggacac ucagcuccuc aacccaagca      840

agccuagaaa uagacucacu auucgaaggc aucgacuucu acaccucgau cacccgugca      900

cguuucgaag aacuaugcag cgaccucuuc cgcucaaccc uagaacccgu agaaaaagca      960

cuacgagacg cgaaacuaga caaagcgcaa auacacgacc ugguccuagu aggaggcuca     1020

acaagaauac cuaaaguaca aaaacucuug caagauuucu ucaauggccg cgaccucaac     1080

aaaagcauaa acccagacga agccgucgca uauggagccg cggugcaggc agcaauccua     1140

augggagaca aaagcgaaaa cgugcaagac cugcugcucc uagacguagc accacucuca     1200

cuuggccucg aaaccgcagg aggcguaaug acugcacuua ucaaaaggaa cucgaccaua     1260

cccaccaaac agacacaaau cuucacuaca uacucggaca accagcccgg aguccuuauc     1320

caaguauacg agggcgaacg cgcgaugaca aaagacaaca accuacucgg aagauucgaa     1380

cucucaggaa uaccaccagc cccacgcggc gucccacaaa ucgaaguaac auucgacauc     1440

gacgcgaacg gaauauuaaa cgucacagcc acagacaaau cgaccggaaa agcaaacaaa     1500

auaacaauca caaacgacaa aggccgacuu aguaaagaag aaaucgagcg aauggugcaa     1560

gaagcggaga aauacaaagc agaagacgaa guacaaagag agcgaguauc cgccaagaac     1620

gcccucgaau cauacgccuu caacaugaaa agcgcggucg aagacgaagg ccuaaagggg     1680

aagauaagcg aagcagacaa gaagaaagua cuagacaaau gccaagaggu aaucagcugg     1740

cuagacgcaa acacccucgc ugaaaaagac gaguucgaac acaaacgaaa agaacucgag     1800

caagucugca accccauaau cucgggccuc uaucagggag cgggaggacc cggcccaggg     1860

ggcuucggag cgcaaggacc caaaggcggc agcggaagcg gccccacaau cgaagaagua     1920

gacuag                                                                1926


<210>  1038
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  1038
auggccacag ccaaggggau cgcaaucggc aucgaccuag gaaccacaua uuccugcgua       60

ggagucuucc agcacggcaa aguggaaaua aucgcaaacg aucaaggcaa cagaacaacc      120

ccaagcuacg uagcauucac cgacacagag agacugaucg gcgacgccgc gaaaaaccaa      180

guggcaauga acccacagaa caccgucuuc gacgccaaac ggcucauagg cagaaaauuc      240

aacgaccccg uaguacaagc cgacaugaaa cucuggcccu uucaagucau aaacgaaggc      300

ggaaagccca aaguccuagu aagcuacaaa ggcgaaaaca aggccuucua ccccgaagaa      360

aucucgagca ugguccucac caagcugaag gaaacagcag aagccuuccu aggccaccca      420

guaacaaacg ccguaauaac agugccagca uacuucaacg acagccaacg acaagcgacc      480

aaggaugcgg guguaauagc gggccucaac guccuacgaa ucauaaacga accuacagcg      540

gccgccaucg ccuacggacu ggacaaagga ggccagggag aaagacacgu acugauauuc      600

gaccuaggag gcggcaccuu cgacgucuca auacugacca ucgacgaugg caucuucgaa      660

guaaaagcca cugcaggcga cacccaccuc ggcggcgaag acuucgacaa ccggcucguc      720

agccauuucg ucgaagaauu uaaaaggaaa cacaagaaag acaucuccca gaacaaaaga      780

gcagucagac gacuucggac cgcgugcgaa cgcgcaaaac gcacgcuaag cagcaguaca      840

caagcaaacc uagaaaucga cucccuuuac gaaggaaucg acuucuacac aucaaucacc      900

cgcgcaaggu ucgaggagcu cugcgccgac cucuuccgug gcacccuaga acccgucgaa      960

aaagcacucc gcgacgccaa aauggacaag gcaaaaauac acgacaucgu acucgucggg     1020

ggcucaacca gaauccccaa gguccagcgc cuacuacaag auuacuucaa cggacgagac     1080

cucaacaaaa gcauaaaucc agacgaagcg gucgcguacg gcgcagcagu acaggccgcg     1140

auccuaaugg gggacaaaag cgaaaaaguc caagaccucc uccugcuaga cguagcaccg     1200

cuuucccuag gccuagaaac agccggaggu guaaugaccg cccuaaucaa acgcaacagc     1260

acaauaccca ccaaacaaac ccaaaucuuc accacauaca gcgacaacca gccgggcguc     1320

cucauacagg uuuacgaagg cgaacgcgca augacaaaag acaacaacuu acuaggacga     1380

uucgaccuga ccggcauccc accagcaccc agaggcgucc cccaaauaga aguaaccuuu     1440

gacauagacg ccaacggcau acuaaacgua acagccacag acaaaaguac gggcaaaguc     1500

aacaaaauca ccauaaccaa cgacaaaggc aggcucucaa aagaagaaau cgaacggaug     1560

guccuagacg cagaaaaaua caaagcagaa gacgaaguac agcgagagaa aauagcggcc     1620

aaaaacgcac ucgaaagcua cgccuucaac augaaaagcg uuguauccga cgaaggauua     1680

aaaggaaaaa uaagcgaaag cgacaaaaac aaaauacucg acaaaugcaa cgaacuccug     1740

uccuggcugg aaguaaacca acucgccgaa aaagacgagu ucgaccacaa acgaaaagaa     1800

cucgaacaaa ugugcaaccc cauaaucacc aaacuguacc aaggcgguug caccggacca     1860

gccugcggaa ccggcuaugu acccggacgc ccagcgacag gcccaaccau cgaagagguc     1920

gacuaa                                                                1926


<210>  1039
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  1039
augagcgcac gcggccccgc aaucgggauc gaucuaggca ccacauacuc gugcguaggc       60

guauuccaac acgggaaagu cgaaaucauc gcaaacgacc aaggaaaccg caccaccccc      120

agcuacguag ccuucaccga caccgaacga cucaucggag acgcagccaa aaaccaggua      180

gcaaugaacc caaccaacac aaucuucgac gcaaaaaggc ugauaggccg aaaauuugag      240

gacgccacgg uccaaaguga caugaaacau uggcccuucc gcguaguauc cgaaggaggc      300

aaacccaaag uccaaguaga auacaagggc gagaccaaga ccuucuuccc ggaagaaaua      360

uccagcaugg uccugaccaa aaugaaagaa auagccgaag ccuaccuugg gggaaaaguc      420

cacagcgccg ucauaaccgu uccagccuac uucaacgaca gccaacggca agccacgaaa      480

gacgcaggca caauaacagg acucaacguc cuucgaauaa uaaacgaacc aaccgcagcc      540

gcgaucgcau acgggcucga caaaaagggg ugugcagggg gcgagaaaaa cguguuaaua      600

uuugaccuag gcgggggcac cuucgacgua agcauccuca ccauagaaga cggcauauuu      660

gaagucaaaa gcaccgccgg agacacacac cugggaggag aagacuucga caaucggaug      720

guaagccacc ucgcagaaga guucaagcgc aagcacaaga aagacauugg gccaaacaaa      780

agggccgugc gacgccucag aaccgcaugc gaacgcgcaa aacgcacccu gagcucaagu      840

acgcaagcaa gcaucgaaau ugacagucug uacgaaggag uagacuucua cacaucaaua      900

acacgagcac gcuucgaaga acucaacgcc gaccucuucc gcggaacacu agaacccguc      960

gaaaaagcac uccgggacgc aaaacuggac aaaggccaaa uccaagaaau aguacucguc     1020

gggggaucca cccgaauacc aaagauacag aaacuacugc aagacuucuu caacgggaaa     1080

gaacuaaaca agucgauaaa ccccgacgaa gcaguagcgu acggcgccgc cguacaagcc     1140

gcgauccuga uaggagauaa aagugaaaac gugcaagacc uacugcuccu ggacgucacg     1200

ccccuaucac ucgggaucga aaccgcuggc ggaguaauga caccccucau aaaaaggaac     1260

accaccauac caaccaaaca aacccaaaca uucaccaccu acucggacaa ccaaucaucu     1320

gugcuaguac aaguauacga aggcgaacgg gcuaugacga aagacaacaa ucuacuaggu     1380

aaguucgacc uaacaggcau acccccggca ccccgaggag uaccacaaau agaaguaacc     1440

uucgacaucg augcaaacgg gauacuaaac guaaccgcag ccgacaaauc gaccggaaaa     1500

gaaaacaaaa ucacaaucac aaacgacaaa ggacgccuca gcaaagacga cauagaccga     1560

augguucagg aagcagagag guacaagagc gaagacgaag cgaaccgaga ccgaguggcg     1620

gccaaaaacg cacuggaaag cuacaccuac aauauaaaac aaacaguuga agacgaaaaa     1680

cuccguggaa agaucagcga acaagacaaa aacaaaauac uagacaaaug ccaagaaguc     1740

auaaacuggc uggaccgaaa ccagauggcc gaaaaagaug aauacgaaca caaacaaaaa     1800

gagcuagagc gcguaugcaa ccccauaauc ucgaaacugu accaaggcgg accaggagga     1860

ggaagcggag gaggaggauc gggcgcaagc ggcggcccga caaucgaaga ggucgacuga     1920


<210>  1040
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  1040
augagcguag uaggcaucga ccuaggguuu cagagcugcu acgucgcagu cgcaagagcg       60

gguggcauag aaacaauagc aaacgaauac agcgacagau gcacccccgc augcaucucg      120

uuuggcccca aaaauagaag cauuggagcu gcagccaaaa gccaagucau cagcaacgcg      180

aaaaacacgg uacaaggcuu caagcgguuu cacggaaggg cauucagcga ccccuucguu      240

gaagcggaga aguccaaccu agcguacgac aucguccaac uacccaccgg acugaccggu      300

auaaaaguaa cauacaugga agaagaaagg aacuuuacaa cagaacaagu aaccgccaug      360

cuccucagca aacuaaaaga aacagcagaa uccguccuca agaaacccgu cgucgacugc      420

gucgugucgg uccccugcuu cuacaccgau gcagaaaggc gcucagucau ggacgcgacg      480

cagauagcgg ggcucaacug ccuacgccua augaacgaga cgacagcagu cgcccucgcc      540

uacggcaucu acaaacaaga ccuucccgca cuagaagaaa aaccccgaaa ugucgucuuc      600

gucgacaugg gacacucagc auaccaagua ucuguaugcg cguucaaccg aggcaaacuu      660

aaagugcugg ccaccgccuu cgacacaaca cucggcggcc ggaaauucga cgaaguccua      720

guaaaucacu ucugcgaaga guucggcaag aaauauaaac uagauauaaa auccaaaaua      780

cgcgcccucc ugcgcuugag ccaggaaugc gaaaaacuca aaaagcuaau gagcgcaaac      840

gcgucagacc ugccacugag cauagaaugc uucaugaacg acguagacgu auccggaacc      900

augaaccggg gaaaauucuu agaaaugugc aacgaccucc uagcacgcgu ugaacccccu      960

cuaagaucug ugcuggaaca aacaaaacug aagaaagaag acaucuacgc aguagaaauc     1020

gucggagggg caacucgaau accggccguc aaagagaaaa ucagcaaauu cuucgggaag     1080

gaacucagca ccacccugaa cgcagacgaa gcgguaacca ggggcugcgc gcuccaaugc     1140

gccauacugu caccagccuu caaaguacga gaguucagca uaacagacgu ggucccauac     1200

ccaauaagcc uccgauggaa cucaccagca gaagaaggcu cgagcgacug cgaaguauuc     1260

agcaaaaacc acgcagcacc auucuccaaa guccucacgu uuuaccggaa agaaccguuc     1320

acccucgagg cauacuacuc cucaccccaa gaccuccccu accccgaccc agccaucgca     1380

caauucagcg uccaaaaggu cacuccccag agcgacggca guagcagcaa agucaaaguc     1440

aaaguccgcg ucaacguaca cgggaucuuc agcguaucau cagccagccu cguggaaguc     1500

cacaagagcg aggaaaacga ggaaccaaug gagaccgacc aaaacgccaa agaagaagag     1560

aaaaugcaag ucgaccagga agaaccccac guagaagaac agcagcagca aacccccgcg     1620

gaaaacaaag cagaauccga agaaauggaa accucgcaag ccggcaguaa agacaagaaa     1680

auggaccaac caccccaagc aaagaaagca aaaguaaaaa cguccacagu agaccugcca     1740

auagagaacc aacuacuuug gcaaauagac cgagaaaugc uaaacuuaua caucgagaac     1800

gaagggaaaa ugaucaugca agauaaacua gaaaaagaaa gaaacgaugc caaaaacgca     1860

gucgaagagu acguuuacga gaugcgggac aaacuaagcg gcgaguacga gaaguucguc     1920

uccgaggacg accgcaacag cuucacacug aaacucgaag acaccgaaaa cuggcuauac     1980

gaagacggcg aagaccaacc aaagcaagua uacgucgaca agcucgcgga acucaaaaac     2040

cucggccaac caauaaaaau ccgguuccaa gaaagcgagg agagaccaaa gcuauucgaa     2100

gaacucggaa aacaaaucca gcaauacaug aaaauuauau caaguuucaa aaacaaagaa     2160

gaucaauacg aucaucugga cgccgcagac augacaaaag uagaaaaauc gaccaacgaa     2220

gcaauggaau ggaugaacaa caaauuaaau cugcaaaaca aacaaagccu aaccauggac     2280

cccguaguaa aaucaaaaga gaucgaagcc aaaaucaaag aacucaccuc cacaugcagc     2340

cccaucauaa gcaaacccaa gcccaaaguc gaaccaccca aagaggaaca gaaaaacgca     2400

gaacaaaacg gccccgucga uggacagggc gauaaccccg gaccgcaagc cgccgaacaa     2460

ggcacggaca cagccgugcc cucagacagc gacaagaaac uaccagaaau ggacaucgac     2520

uaa                                                                   2523


<210>  1041
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  1041
augucagucg ucggaauaga ccucggauuc cucaacugcu acauagccgu agcacgcucc       60

ggagguauag agacaaucgc caaugaguac uccgacaggu guacccccgc gugcaucagc      120

cugggcuccc gcacucgcgc caucggcaac gcggcgaagu cccaaaucgu caccaacguc      180

agaaacacaa uccacggauu caagaaacuc cacggacgau ccuucgacga ccccauaguc      240

caaaccgagc gcauacgccu gcccuacgaa cuacagaaaa ugccaaaugg cagcgccggc      300

guaaaagucc gcuaccucga ggaggaacgc cccuucgcca ucgaacaagu cacaggcaug      360

cuauuagcaa agcucaaaga gaccuccgaa aaugcacuca agaaacccgu ggcagacugc      420

guaaucagca uuccguccuu cuucacagac gcagagcgac ggucagucau ggcagccgca      480

caagucgccg gccugaacug ucuccgacug augaaugaga caacggccgu cgcccucgca      540

uacggcaucu acaaacaaga cuuaccuccg cucgacgaaa aaccgagaaa cgucgucuuc      600

aucgacaugg gacacagcgc auaccaaguc cucguaugug cauucaacaa aggaaaacua      660

aaaguucuug ccaccacauu cgauccauac cucggaggcc gcaacuucga cgaagcacuc      720

guugacuacu ucugugacga guucaaaaca aaauacaaaa uaaacgucaa agaaaacagc      780

cgcgcccuuc uccgucuaua ccaggagugc gaaaaacuca agaaacucau gagcgccaac      840

gccagcgauc ucccacuaaa caucgaaugu uucaugaacg accuggacgu gaguuccaaa      900

augaaccgug cccaauucga gcaacucugc gccagcuuac uagcaagagu agaaccacca      960

cucaaagcgg ucauggagca agccaaucuc caacgggaag acaucagcuc cauagagauc     1020

gucgggggag caacccgaau acccgcugua aaagaacaaa uaacuaaauu cuuccuaaaa     1080

gacauaagca caacccugaa cgccgacgaa gcagucgccc gaggcugcgc acuccagugc     1140

gccauacucu cccccgcguu caaaguacgc gaguucagua ucacagaccu cguaccauac     1200

ucaaucaccc uacgcuggaa gacaucuuuc gaagacggcu ccggagaaug cgaagucuuc     1260

ugcaaaaauc accccgcccc cuuuuccaaa gucaucacau uccacaaaaa ggaaccguuc     1320

gaacucgaag cguuuuacac gaaccuccac gagguaccau accccgacgc gagaauagga     1380

ucauucacca uacaaaacgu auucccacaa uccgacggcg auucauccaa ggucaaaguc     1440

aaaguaagag ucaacauaca cggcaucuuu ucagucgcca gcgccagcgu gauugagaaa     1500

caaaaccuug aaggcgauca cagcgacgcc cccauggaaa ccgaaacgag cuucaagaac     1560

gaaaacaagg acaacaugga caagaugcag guagaccaag aggaaggaca ccaaaaaugc     1620

caugcagaac acacacccga ggaagaaauc gaccacaccg gagccaaaac gaagucugcc     1680

gucagcgaua agcaggaccg ucucaaccaa acccucaaga aaggcaaagu aaaaagcaua     1740

gaccuaccaa uccaaagcuc acucugccgc caacucgggc aagaccuccu aaacuccuac     1800

auagaaaacg aaggcaaaau gaucaugcaa gauaaacuag aaaaagaacg caacgacgcc     1860

aaaaacgcag ucgaagaaua cgucuaugac uuccgagacc ggcucggaac cgucuacgaa     1920

aaauucauaa cccccgagga ccuaucaaaa cuaagcgcug uccuagaaga caccgagaac     1980

uggcuauacg aagacggaga ggaccaacca aaacaaguau acguagacaa gcuccaggag     2040

cucaagaaau acggccaacc cauccagaug aaauacaugg agcaugaaga aagacccaaa     2100

gcacucaacg accucggcaa gaaaauccag cucguuauga aaguaauaga agccuaccga     2160

aacaaagacg agcgcuacga ccaccuagac ccaaccgaaa uggaaaaagu cgaaaaaugc     2220

aucagcgaug ccaugagcug gcucaacucc aagaugaacg cgcagaacaa acuaucccuc     2280

acccaagacc ccguaguaaa aguaucagaa auagucgcaa aaucgaaaga acuggacaac     2340

uucugcaacc caaucaucua caagccgaaa ccuaaagcag aggugccaga agacaaacca     2400

aaagcaaaua gcgaacacaa cggaccaaug gacgggcaau ccggaacaga aaccaaaagc     2460

gauagcacaa aagacucauc ccagcacaca aaaagcucag gggaaaugga ggucgacuag     2520


<210>  1042
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  1042
augaaacuaa gccuaguagc ggcaaugcuc cugcucuuaa gcgccgcaag agcagaagaa       60

gaggacaaga aagaggacgu cggcaccguc gucggcauag accuaggcac cacguacagc      120

ugcgucgggg uauucaaaaa cggaagaguc gaaaucaucg ccaacgacca aggcaacaga      180

aucacaccca gcuacguagc cuucaccccc gaaggagaac gccucauagg agacgcggcc      240

aaaaaccaac ucaccagcaa cccagagaac acaguauucg acgcaaaacg gcuaaucggc      300

cggaccugga acgaccccag cguccaacaa gacauaaaau uccuccccuu caaggucguc      360

gagaagaaaa caaaaccaua cauucaaguc gacauaggag gaggucaaac gaaaacauuc      420

gcacccgagg agauaagcgc aaugguacuc accaaaauga aagaaaccgc agaagcauac      480

cuuggaaaga aagucacgca ugccgucguc acagucccag ccuacuucaa cgacgcacaa      540

agacaggcga ccaaagacgc cggcacaauc gcaggacuga acguaaugcg cauaaucaac      600

gagcccaccg ccgcagccau cgcuuacggg cuagacaaac gagaaggaga gaaaaacauc      660

cucguguucg accuaggagg aggcacauuc gacgucagcc uccuaacaau cgacaacgga      720

guguucgaag ucguagccac caacggcgac acgcaccucg gaggagagga uuucgaccaa      780

agaguaaugg aacacuuuau caaacuauac aaaaagaaaa caggcaaaga cguacgaaaa      840

gacaacagag ccgugcaaaa acuucgacgu gagguagaaa aagccaaacg agcacugucg      900

agccaacacc aagcaagaau agaaaucgag agcuucuacg aaggcgaaga cuucagcgaa      960

acccucacuc gagcaaaauu ugaagaacua aacauggacc ucuucagaag cacaaugaag     1020

ccaguacaga aggugcucga agacucagac cucaagaaaa gcgauauaga cgaaaucguc     1080

cucgucgggg gcagcacccg gauaccgaaa auccaacaac ucgucaaaga guucuucaac     1140

ggaaaagaac cuagccgugg aaucaaccca gacgaagccg ucgcguacgg agccgcgguc     1200

caggcaggcg uccuaucagg cgaucaagac acaggcgacc ucguccuacu agacgugugc     1260

ccacuaacac ucggaaucga aaccgugggc ggagucauga ccaaacuaau accccgcaac     1320

acagucguuc ccacgaagaa aagccaaaua uucagcacgg ccucagacaa ccagcccacc     1380

guaacaauca aagucuacga aggggaacgc ccacucacca aagacaacca ccuccugggc     1440

acguucgauc ugacaggcau accacccgcg ccccgcggag ucccgcaaau cgaaguaaca     1500

uucgaaauag acgugaacgg gauacugcgc gucacagccg aagacaaagg aaccggaaac     1560

aaaaacaaaa ucacaauaac aaacgaccaa aaccgccuaa caccagaaga aauagaaaga     1620

augguaaacg acgccgaaaa auucgcagaa gaggacaaga aacuaaaaga acgcauagac     1680

acccgaaacg aacucgaauc auaugcauac ucccucaaaa accagaucgg cgacaaagaa     1740

aaacuagggg gcaaacugag cuccgaggac aaggaaacaa uggaaaaagc aguagaggag     1800

aaaaucgaau ggcuggaaag ccaucaagac gcagacauag aggacuucaa agccaagaag     1860

aaagaacuug aagagaucgu acaaccaaua aucucaaaac ucuacggcuc ggcaggacca     1920

ccaccgacag gagaagaaga cacggccgaa aaagacgaac uguag                     1965


<210>  1043
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  1043
augcaagccc caagagaacu agccgugggg aucgaccucg ggacaacaua cuccugcgua       60

ggcguguucc aacaaggaag agucgaaaua uuagcaaacg accaaggcaa caggaccaca      120

ccaucguacg uagcguucac agacacagaa cgccuagugg gagacgcagc aaagucgcaa      180

gcagcacuaa auccacacaa cacggucuuc gacgcaaaga ggcuaauagg aaggaaguuc      240

gccgacacaa ccguucaaag cgauaugaag cacuggccau ucagagucgu cucggaagga      300

gggaaaccaa aagugcgggu cugcuacaga ggcgaagaca aaacauucua cccagaagag      360

aucuccagca ugguacugag caaaaugaag gaaacagccg aagccuaccu cggccaacca      420

gucaagcacg cggucauaac cguacccgcc uacuucaaug acagccagcg ccaagccaca      480

aaagacgccg gggcaauagc cggacuaaac guacuacgaa ucaucaacga acccacggca      540

gcagcgauug cauacggccu agaccgaagg ggcgccggag aacgcaaugu ccugauauuc      600

gaccugggag ggggcacauu ugacgucucc guacuaucaa uagacgcagg aguauucgaa      660

gugaaagcga cggcaggaga cacgcaccua ggcggcgaag acuucgacaa ccgucuagug      720

aaccacuuca uggaagaguu caggcgaaaa cacggaaaag aucucagcgg aaacaaacgc      780

gcacuccgca ggcuaagaac cgcaugcgaa cgcgcaaaaa ggacccuaag cuccucgaca      840

caggccaccc ucgaaauaga cucccuauuc gaaggagucg acuucuacac aagcaucacc      900

cgcgcgcgau ucgaagaacu augcagcgac cuuuuccgcu caacccuaga accagucgaa      960

aaagcucucc gcgacgcaaa auuagacaaa gcacaaaucc acgaugucgu ccuaguaggc     1020

ggcucaacgc gcauaccaaa aguacaaaag cuccugcaag acuucuucaa cgggaaagaa     1080

cuaaacaaau ccauaaaccc cgacgaagcg gucgccuacg gcgcggcggu acaagcagcg     1140

guccugaugg gcgacaagug cgaaaaagug caagaccuac uacuccucga cgucgcccca     1200

uuaagccucg gacuggagac ggcaggagga guaaugacaa cacuaaucca gcgaaacgcg     1260

accauaccca caaagcaaac ccaaaccuuu accacguacu cagacaacca accgggaguc     1320

uucauccaag uauaugaggg cgaacgcgca augacaaaag acaacaaccu cuugggccgc     1380

uucgaacucu ccggcauccc acccgcgccc cgaggcguac cgcaaauaga agugaccuuc     1440

gacauagacg ccaacgggau acuaagcgua accgcgacag accggucaac cggcaaagcg     1500

aacaaaauca caaucaccaa cgacaaagga cggcuaagca aagaagaagu agaacgcaug     1560

guccacgaag ccgaacaaua caaagccgaa gacgaagccc aacgugaccg cgucgcagcg     1620

aaaaacucac ucgaagccca cguguuccac guuaaaggau cccuccaaga agaaagccug     1680

cgcgacaaga uacccgaaga agaccggaga aaaaugcagg acaaaugccg ugaaguacuc     1740

gccuggcucg aacacaacca acuagccgaa aaagaagaau acgagcauca aaaacgagaa     1800

cuggaacaaa uuugcagacc cauauuuucg agacuguacg ggggcccagg cgucccagga     1860

ggcucaagcu gcggaaccca agccagacaa ggagacccca gcacaggacc aaucauagag     1920

gaaguagacu ag                                                         1932


<210>  1044
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__P48741__HsHSPA7

<400>  1044
augcaagcac cccgcgaacu cgcaguaggc aucgaccuag gcaccaccua cuccugcgua       60

ggcgucuucc aacaaggccg cguagaaaua cucgccaacg accaaggcaa ccgcaccacc      120

cccuccuacg ucgcauucac cgacaccgaa cgccucguag gcgacgccgc uaaaucccaa      180

gccgcccuaa acccccauaa caccgucuuc gacgccaaac gacucaucgg ccgaaaauuc      240

gcagacacca ccguacaauc cgacaugaaa cacuggccuu uccaagucgu aucagaagga      300

ggaaaaccaa aaguccgcgu cugcuaccgc ggagaagaca aaacuuucua ccccgaagaa      360

auauccagca ugguccuauc aaaaaugaaa gaaaccgccg aagcauaccu cggccaaccc      420

gucaaacacg ccgucaucac cgucccaacc uacuucucca acucccaaag acaagccacc      480

aaagaugcag gcgccauagc cggccuaaaa guacucccca ucaucaacga ggccaccgcc      540

gcagccaucg ccuauggacu agaucgccgc ggcgccggca aacgaaacgu ccugauauuc      600

gaccucggcg gcggcaccuu cgacgucuca guacucagca uagacgcagg cgucuucgaa      660

guaaaagcaa ccgcaggaga uacacaucuc ggcggcgaag acuucgacaa ucgacuuguc      720

aaccacuuca uggaagaguu cagacgcaaa cacggcaaag accuaucagg caacaaacgc      780

gcccuacgcc gccuacgaac cgccugcgaa agagccaaac gaacacccag cuccucuacg      840

caagcaacac ucgaaauaga cucccucuuc gaaggcgucg acuucuacaa auccaucacc      900

cgagcacgau ucgaagaauu augcuccgac cuguuccgca gcacccucga acccguagaa      960

aaagcccuca gagacgcaaa gcuggacaaa gcccaaaucc acgacuucgu ccucggaggc     1020

ggccuccacu cccaccccca aggcgcagaa guagcugcag gccuccuaca acgacaggga     1080

gccgaacaag aacaccaacc cuaa                                            1104


<210>  1045
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  1045
augucaaaag gaccggccgu cggaaucgac cucggcacca ccuacagcug cgucggcgug       60

uuccaacacg gaaaagugga aaucaucgca aacgaucaag gcaacaggac cacacccucg      120

uacguggcau uuaccgacac cgaacgccuc auuggagacg cggccaaaaa ccagguagca      180

augaacccca ccaacaccgu cuucgacgca aaaaggcuaa ucggcagacg auucgacgac      240

gcagucgucc agagcgacau gaaacacugg ccauucaugg uggucaauga cgcaggccga      300

ccaaaagucc aagucgaaua caaaggcgaa accaagagcu ucuaccccga agaaguaucc      360

agcauggugc ugaccaaaau gaaagaaaua gcagaggcau accuaggaaa gaccgucacg      420

aacgcagucg ugacaguacc cgcauacuuc aacgacucac aacgccaagc cacaaaagac      480

gccggaacaa uagccggccu aaacguacua cgcauaauaa acgaaccaac agcagcagca      540

aucgccuacg gacucgacaa aaaggucggg gccgaacgca acguccuaau cuucgaucua      600

ggaggaggga cauucgaugu cagcauccug acaauagaag acgggauauu cgaagucaaa      660

agcacagccg gcgacaccca ccucggagga gaagauuucg acaaccgcau ggucaaccac      720

uuuauagccg aguucaagcg caagcacaag aaggacauca gcgaaaacaa acgagccgua      780

cgccgacuac gcaccgccug cgaacgagca aaacgcaccc ugucaagcag cacgcaagcg      840

agcauagaga ucgacagccu cuacgaaggc auagacuucu acacauccau aacgcgagca      900

cgguucgaag aacucaacgc cgaccuguuc cgcggcaccc uagacccagu agaaaaagcc      960

cuacgagacg ccaaacucga caaaucacaa auccacgaca uaguucuggu cggcggcucc     1020

acaagaaucc cuaaaaucca aaaacuacuc caagacuucu ucaacggaaa agaacucaac     1080

aaaagcauaa accccgacga agcaguggcg uacggagcag ccguccaagc cgcgauccua     1140

uccggcgaca agagcgaaaa cguucaagac cuucuccucu uggacguaac cccgcuauca     1200

uuaggaauag aaaccgcggg aggaguaaug acaguacuaa ucaaaaggaa cacuacaaua     1260

ccgaccaaac aaacacaaac cuucacgaca uacucagaca accaaccagg cgugcucaua     1320

caagucuaug aaggagaacg cgcaaugaca aaagacaaca accuacucgg caaguucgaa     1380

cucacaggga ucccacccgc accccgcgga guaccacaaa uagaaguaac cuucgacauc     1440

gacgccaacg gaauccucaa cgucagcgcc gucgacaaau caacaggaaa agagaacaaa     1500

aucacgauaa caaacgacaa agggcgccug agcaaagaag auaucgaacg aaugguucag     1560

gaagccgaga aauacaaagc agaggacgaa aagcaacgcg acaaagucag cuccaaaaac     1620

ucccuagaau cauacgcguu caacaugaaa gcgacggucg aagacgaaaa acuacaaggc     1680

aaaauuaacg augaggauaa acagaaaaua cuagacaagu gcaacgaaau cauaaacugg     1740

cucgacaaga accaaacagc agaaaaagaa gaguucgaac aucaacaaaa agaacucgaa     1800

aaagucugca aucccauaau aaccaaacug uaccaaagcg cgggcgggau gcccggcggu     1860

augccgggag gcuuccccgg aggcggcgcc ccaccaagcg gcggcgcauc cucaggccca     1920

accaucgaag aagucgacua a                                               1941


<210>  1046
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  1046
augauaagcg ccagccgcgc agccgcggcg aggcuaguag gcgcagcggc aaguagagga       60

ccgacggcgg caagacacca agacucaugg aacggccuga gccacgaggc guucagacug      120

gugagccgac gcgacuacgc aagcgaggcc aucaaaggag cagucgucgg aaucgaccua      180

gggacgacga acucgugcgu agcagugaug gagggaaagc aggcgaaggu ccuggagaac      240

gcggaaggag cgagaaccac gccaucaguc guagcauuca ccgcggacgg agagaggcuc      300

gugggaaugc cagcgaaaag gcaggcagua acaaacccaa acaacaccuu cuacgcgaca      360

aaaaggcuaa uagguagaag auacgacgau ccagaagugc aaaaggacau caaaaacgua      420

cccuucaaga uaguacgagc cagcaacgga gacgcauggg uagaggcaca uggcaagcua      480

uauagcccga gccagauagg ggcguucguc cucaugaaga ugaaggaaac ggcagagaac      540

uaccugggac acacggcaaa gaacgcgguc auaacagugc cagcguacuu caacgacagc      600

caacggcaag cgacaaagga cgcagggcag auaaguggac ucaacguccu acgcgucaua      660

aacgaaccaa cagcggcugc ccucgcauac gggcucgaca agagcgaaga caaaguaaua      720

gcaguauacg accugggcgg aggcacauuc gacauaucua uacuagaaau ccagaaaggg      780

guauucgaag uaaaguccac aaacggcgac acguuccuug gaggggaaga cuucgaccaa      840

gcgcuauugc gucacaucgu aaaggaguuc aagagagaga caggaguaga ccucacaaaa      900

gacaacaugg cgcugcaacg aguaagagaa gcagcagaaa aagcgaagug ugaacuaagc      960

ucuagcguac aaacagacau uaaccuccca uaucucacaa uggacaguuc agggccgaaa     1020

caccuaaaca ugaagcucac aagagcccag uucgagggaa uagugaccga ccuaauccgc     1080

aggacaauag cgccgugcca aaaggcgaug caggacgcag aagugagcaa gagcgacauc     1140

ggagaaguca uauuaguagg gggaaugacc aggaugccga aagugcaaca gacggugcag     1200

gaccuguucg gcagagcacc gagcaaggca guaaacccag acgaggcagu agcgaucgga     1260

gcggccauac aagggggagu acuugcggga gacguaacgg acguacuacu auuggacgug     1320

acgccauuaa gccuaggaau agaaacacua gguggcgugu ucacuaaacu caucaaucga     1380

aacaccacga uacccacaaa gaaaucacaa guguucagca cagcggccga cggacagacc     1440

caggucgaga uaaaaguaug ccaaggagag cgagaaaugg ccggggacaa caaacuacuc     1500

gggcaauuca cacugauagg aauaccgcca gcacccaggg gaguacccca gauagaggua     1560

acauucgaca ucgacgcgaa cggaauaguc cacgucagcg caaaagacaa aggaacuggc     1620

agggagcaac aaauagugau ccaaagcagc ggcggacuga gcaaggacga cauagagaac     1680

auggugaaaa acgcggaaaa auacgcggag gaggacagga gaaagaaaga aaggguagaa     1740

gcaguaaaua uggcggaagg gauaauacac gauaccgaga ccaagaugga agaguucaag     1800

gaucaacucc cagcggacga augcaacaaa uuaaaagaag aaauaagcaa gaugagggaa     1860

cuacuagcgc gcaaagauag cgaaacggga gaaaacauaa gacaagccgc gagcagucuc     1920

cagcaggcca gccuaaaacu auucgaaaug gcguacaaga aaauggcaag cgaaagagaa     1980

gggagcggga gcagcggaac aggagagcaa aaagaagauc agaaagaaga gaagcaguaa     2040


<210>  1047
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  1047
auggccgaca aagaggcagg cggaagcgac ggaccccgag aaacagcccc aacauccgcc       60

uacuccagcc cagcaagauc acucggcgac accggcauca caccacucuc accgucucac      120

aucgucaacg acaccgauuc aaacguaucc gagcaacaau ccuuccuagu agucgucgcc      180

gucgacuucg ggacaaccuc cuccggcuac gcauauuccu ucacaaaaga acccgaaugc      240

auccacguca ugcgccgcug ggaaggagga gaccccggcg uauccaacca gaaaacgccc      300

acuaccaucc uacuaacccc cgaacgaaaa uuccacuccu ucggcuacgc ugcccgagac      360

uucuaccacg accucgaccc aaacgaagcc aaacaauggc ucuaccuaga aaaguucaaa      420

augaaacuuc auaccacagg cgaccucacc auggacaccg aucuaaccgc cgcaaacggc      480

aagaaaguga aagcucuuga aaucuucgcc uacgcccuuc aauacuucaa agaacaagca      540

cuaaaagaac ucuccgacca agcaggcuca gaguucgaaa acuccgacgu ucgcuggguc      600

aucacagucc ccgcaauaug gaaacaaccc gccaagcaau ucaugcgaca agcagcauac      660

caagccgguc ucgcaagccc agaaaauuca gaacaauuaa ucauagcacu cgaacccgaa      720

gccgcgucca uauacugccg caaacuucgc cuccaccaaa ugauagaacu cuccucaaaa      780

gccgcuguca acggguacuc cgguagcgac acagucggcg ccggcuucac acaagccaag      840

gagcacauac gccgcaaccg ccaaucgcga acauuccucg ucgagaacgu caucggagaa      900

aucuggucag aacucgaaga aggcgacaaa uacgugguag ucgacagcgg cggcggaacc      960

guggaccuaa ccguccacca gauacgccug ccagaagggc accuuaaaga auuguacaaa     1020

gccacaggag gacccuacgg aucauuagga gucgacuacg aguucgaaaa gcugcucuac     1080

aaaaucuucg gcgaagauuu cauugaacaa uucaaaauaa aacgccccgc cgcauggguc     1140

gaucugauga uagccuucga aucacguaaa cgcgcagccg cucccgaccg aaccaaucca     1200

cucaacauca cccuacccuu cucauucauc gacuacuaua agaaauuccg cgggcacucc     1260

gucgaacaug cucuccgaaa aucaaacguc gauuucguca aauggucauc ccaaggcaug     1320

cuccgcaugu caccggacgc caugaacgca cuauucaaac ccacuauaga cucaauaauc     1380

gaacaccuac gcgaccucuu ccaaaagccc gaaguaagca cagucaaauu ccucuuccuc     1440

gugggcgggu ucgccgaagc cccacuccuc caacaggccg uccaggccgc auucggagac     1500

cagugccgua ucauaauccc acaagacgua ggccuaacca uacucaaagg cgcaguccua     1560

uucggccuag accccgccgu cauuaagguc cgccguuccc ccuuaacaua cggagucggc     1620

guccuuaacc gcuaugucga aggaaaacac ccacccgaaa agcuccuagu caaggacggc     1680

acccgauggu gcaccgacgu cuucgacaaa uucauauccg cagaccaaag cguugcacuc     1740

ggcgaacuug ucaaacgauc auacaccccc gcgaaacccu cacaauuagu cauagucaua     1800

aacaucuacu ccucagaaca cgacaacguu uccuucauca ccgaccccgg cguaaagaaa     1860

ugcggaaccc ucagacugga ccucaccggc acauccggca cugccguacc cgcacgacgc     1920

gaaauacaaa cccucaugca guucggcgac accgaaauca aagcaacugc caucgacaua     1980

gccacaucaa aauccguaaa aguaggaauc gacuuccuaa acuacuaa                  2028


<210>  1048
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  1048
augcuagcag uccccgaaau gggccuacaa ggccucuaca ucggcuccag ccccgaacgu       60

ucacccguac ccucaccacc aggcucacca agaacccaag aaaguugcgg caucgcccca      120

cucacgcccu cccaaucccc caagcccgaa guccgagcac cccaacaggc uucauucucu      180

gucgucguag caauagacuu cggaaccacc ucuagcggcu acgcuuucuc auucgccagc      240

gaccccgaag ccauccacau gaugcgcaaa ugggaaggag gagaccccgg uguagcacac      300

cagaaaaccc caaccugccu acuccucaca cccgaaggag ccuuccacag cuucggcuac      360

accgcccgag acuacuacca cgaccucgac cccgaggagg cucgugacug gcucuacuuc      420

gaaaaauuca aaaugaaaau ccacuccgcc accgaccuca cccucaaaac ucaacuagaa      480

gcgguuaacg gaaaaacaau gcccgcccua gaaguuuucg cacacgcccu gcgcuucuuc      540

cgagaacacg cacuccaaga acuucgcgaa caaagcccga gccuuccuga aaaagacacc      600

guucgauggg ucuugacagu ccccgcaaua uggaaacaac cggcgaaaca auucaugcga      660

gaagcagccu accuagccgg acugguaucc cgagaaaacg ccgagcaacu acucaucgca      720

cucgaacccg aagcugcauc cgucuacugc cgcaaacuac gccuccacca acuccucgac      780

cuguccggcc gcgcaccagg aggcgguaga uugggugagc gacgcaguau agacaguucc      840

uuucgacaag cacgcgaaca gcuacgccga agccggcacu cccgaacuuu ccuuguagaa      900

ucaggcgucg gcgaacucug ggccgaaaug caagcaggag acagauacgu aguugcggac      960

ugcggcggcg gcaccguuga ccugacaguc caccaauuag aacaaccaca cggcacucuc     1020

aaagaacuuu acaaagcauc cggcggaccc uauggcgccg uaggagucga cuuagcauuu     1080

gaacaacucc ugugcagaau cuucggggaa gacuuuauag caaccuucaa aagacaaaga     1140

cccgcagccu gggucgaccu uaccaucgca uucgaagcac ggaaacgaac agccggccca     1200

caccgagcag gagcccugaa caucagccua ccauucucau ucaucgauuu cuaccggaaa     1260

caacgcggcc acaacgucga aacagcccuc cggcgaagca gcgucaacuu cgucaaaugg     1320

ucaucccaag gaaugcuacg aauguccugc gaagcaauga acgaacucuu ccaaccaacc     1380

gucucgggca ucauccaaca caucgaagcc uuacuagccc gcccagaagu acaaggaguc     1440

aaacuccucu uccuagucgg aggcuucgca gaguccgcag uccuacaaca cgcgguucag     1500

gccgccuuag gagcacgcgg ccuccgaguc gugguacccc acgacguagg ccucacaauc     1560

cuaaaaggcg ccguucucuu cgggcaagcu cccggcgucg uacgcguacg ccgcagccca     1620

cuaaccuacg gcguuggcgu acucaaccgc uucgucccgg gaagacaccc acccgaaaaa     1680

cuccuagucc gagacgguag acgcuggugc accgacgucu uugaaagauu cguggccgcc     1740

gaacaaucag ucgcccucgg cgaagaaguc cgacgcagcu acugccccgc acgccccggc     1800

caacgacgcg uccucaucaa ccuauacugc ugcgcagcag aagacgcacg cuuuauaacc     1860

gaccccggcg uccgaaaaug cggcgcacuc ucacucgaau uagaacccgc agacugcggu     1920

caagacaccg ccggagcccc gcccggaaga cgagaaaucc gcgccgcaau gcaauucggc     1980

gacaccgaaa ucaaagucac agccgucgau gucuccacaa accgaagcgu aagggccucg     2040

auagacuucc uaaguaacua g                                               2061


<210>  1049
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  1049
auggcaagag aaaugacaau ccuuggcucc gccgugcuaa cccuccuacu agccgguuac       60

cucgcccaac aguaccuacc ccuccccacc ccaaaaguca ucggaaucga ucucggcacc      120

accuacugcu cagucggcgu cuucuucccc ggcaccggaa aaguaaaagu uauaccggac      180

gaaaacggcc acaucuccau ccccucaaug gucuccuuca ccgacaacga cgucuacguc      240

ggcuacgaaa gcguggaacu cgccgacucc aacccccaaa auacaauaua cgacgccaaa      300

cgcuucaucg gcaaaaucuu caccgccgaa gaacucgaag ccgaaauagg ccgcuacccu      360

uucaaagugc ucaacaaaaa cggcaugguc gaguucuccg ucaccagcaa cgaaacaaua      420

acaguaucgc cagaauacgu cggcucccgc cuccuccuua aacuaaaaga aauggcagaa      480

gccuaccuag gcaugcccgu cgccaacgca guaaucucag ucccagccga guucgaccuu      540

aaacaaagga acuccaccau cgaagcagcu aaccucgccg gccugaaaau ccuccgaguc      600

aucaacgaac ccaccgccgc ggccauggca uacggacuuc acaaagccga cgucuuccac      660

guccucguaa ucgaccuggg cggcggcacc cuagacguca gccuucucaa caaacaggga      720

ggcauguucc ucacacgcgc gaugucagga aacaacaaac uaggaggcca ggacuucaac      780

caacgccuac uccaauaccu auacaaacaa auauaccaaa ccuacggauu cguuccaucc      840

cgaaaagaag aaauccacag acuccgacaa gcaguagaaa ugguaaaacu caaccuaacc      900

cuacaccaau ccgcacaacu aagcguccuc cuuacaguag aagaacaaga ccgaaaagaa      960

ccacacuccu ccgacaccga acuccccaag gauaagcuau ccagcgcuga cgaccacaga     1020

guaaacuccg guuucggccg uggccucagc gacaagaaau cuggugaauc acagguccua     1080

uucgaaaccg agauaucccg aaaacucuuc gacacccuca acgaagaccu cuuccagaaa     1140

auccucgucc ccauccaaca aguccucaaa gaaggccacc ucgagaaaac agaaaucgac     1200

gaagucguac ucguaggagg cuccacacgc aucccccgca uccgacaagu aauccaagag     1260

uucuucggca aagaccccaa caccucagua gacccugacc uggccgucgu aaccggaguc     1320

gccauccagg ccggaauuga uggcggaucc uggccccuac aagugagcgc ccucgaaauc     1380

ccaaacaaac accuccagaa aacaaacuuu aacuga                               1416


<210>  1050
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  1050
auggccgcaa uaggcgucca ccuaggcugc accagcgccu gcgucgccgu cuacaaagac       60

ggcagagcag gcguagucgc caacgacgcc ggagaccgcg ucaccccagc agucgucgcc      120

uacagcgaga acgaagaaau cguggggcuc gcagccaaac aaucccgcau ccgaaauauc      180

uccaacacag ucaugaaagu aaaacaaauc cuaggacgca guucgucaga uccccaggcc      240

caaaaauaca uagccgaauc aaaaugccua guaauagaga aaaacggcaa acuccgauac      300

gaaaucgaca ccggugaaga aacaaaauuc guaaacccag aagacgucgc acgccuaaua      360

uucagcaaga ugaaagaaac cgcccacucu gugcucggaa gugacgccaa cgacguaguc      420

aucaccguac cauucgacuu cggcgaaaaa cagaaaaacg cccuaggcga agccgcaaga      480

gccgccgguu ucaacguccu gcgacucaua cacgaaccaa gcgccgcgcu ccucgccuac      540

ggcaucggcc aagacucccc aaccgggaag uccaacaucc uaguauucaa gcuaggaggc      600

accagucuau cccuauccgu cauggaaguc aacagcggca uauaccgcgu acucucaacc      660

aacacagacg acaacaucgg cggagcccau uucaccgaaa cacuagccca auaccucgcc      720

uccgaguucc aacgcucuuu caaacacgac guccgcggca acgcgcgcgc caugaugaaa      780

cuaaccaaca gcgccgaagu agcuaaacac ucacucucaa cacucggcuc cgcaaacugc      840

uuucuugaca gccuauacga aggccaagac uucgacugca acgucucaag agccagguuc      900

gaacuacuau gcucaccacu cuucaacaaa ugcaucgaag ccauacgugg acuacucgac      960

caaaacggau ucacugccga cgacaucaau aaaguaguac ucugcggagg aucuucacga     1020

auaccuaaac uacaacaacu caucaaagac cucuucccag ccgucgaacu ucuuaacucc     1080

aucccacccg acgaagucau ccccaucggc gccgccaucg aagccggcau ccucaucgga     1140

aaagaaaacc uacuuguaga ggacucccuc augaucgaau gcuccgccag agacauccua     1200

gucaaaggcg uagacgagag cggcgccagc cgauucaccg uccuauuccc cuccggaaca     1260

ccacuaccag cccgacgcca acacacacua caagccccag gaucaauauc cuccgucugc     1320

cucgaacucu acgaaagcga cggcaaaaac uccgcaaaag aagaaaccaa auucgcacaa     1380

gucguccucc aagaccucga caagaaagaa aacggccucc gcgacaucuu agcagugcuc     1440

accaugaaac gcgacggcag ccugcacgua acaugcacag accaggaaac cggcaaaugc     1500

gaagccaucu ccauagaaau cgccucauaa                                      1530


<210>  1051
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  1051
augagcguag uaggacucga cguagggagc caauccugcu acauagccgu cgcccgcgcc       60

gguggcaucg aaaccaucgc aaacgaguuc agugaccgau gcacccccuc cguaauaucc      120

uucggaagca aaaacagaac cauaggcgua gcugcuaaaa aucagcaaau cacacacgcg      180

aauaacacgg ucucaaacuu caaacgauuc cacggcagag ccuucaauga ccccuucauc      240

caaaaagaaa aagaaaaccu aucauacgac cuaguacccc ucaaaaacgg aggcguagga      300

aucaaaguca uguacauggg agaagaacac cuauucagcg uagaacaaau aacugccaug      360

cuacucacca aacucaagga aaccgcagaa aacucacuga aaaagccagu caccgacugc      420

gugauaagcg uccccucuuu cuucaccgac gccgaacgcc gaucgguccu agacgcagcc      480

caaauagucg gccuaaacug ucuacgacua augaacgaca ugacagcagu ggcccugaac      540

uacggcaucu auaagcaaga ccugcccucg cucgacgaaa aaccacgcau cguaguauuc      600

gucgauaugg gccacucagc auuccaagug ucagccugcg cauucaacaa gggcaaacuc      660

aaagugcuag gcaccgccuu cgaccccuuu cucggaggca aaaacuucga cgaaaagcua      720

guggaacacu ucugcgcaga auuuaaaacc aaauauaaac ucgacgccaa auccaaaauc      780

agagcccugc uacgacucua ccaagaaugc gaaaaacuaa agaaacugau guccuccaac      840

ucaaccgacc ugccccugaa caucgaaugc uucaugaacg acaaagacgu cuccgggaaa      900

augaacagau cacaauucga agaacuuugc gccgaacuac uccagaaaau cgaaguacca      960

cucuacuccc uccuggaaca aacccaccua aaagucgaag acguguccgc cguagaaauu     1020

gucggcggcg caacacgcau accggccgua aaagaacgaa uagcgaaauu cuucggcaaa     1080

gacaucucca ccacccuuaa cgcagacgaa gccgucgcac gcggcugcgc ccuccagugc     1140

gcaauacucu cgccggccuu caaaguccgc gaguucuccg ucacggaugc cgucccauuc     1200

ccgaucuccc ugauuuggaa ccacgacagc gaagacacug aaggagucca ugagguauuc     1260

agccgaaacc acgcagcucc cuucagcaaa guacucacau uccuacgccg cggaccauuc     1320

gaacuggaag cguucuacag ugacccccag ggaguaccgu acccggaagc aaaaaucgga     1380

cgcuucgugg ugcaaaacgu aucagcacaa aaggacggcg agaaaagccg cgucaaagua     1440

aaaguaagag uaaauacgca cggaaucuuc acaaucucaa cagccucaau ggucgaaaaa     1500

guacccaccg aggaaaacga aaugagcucc gaagccgaua uggaaugccu caaccaacgc     1560

ccacccgaaa accccgauac agacaagaac guccaacaag acaauuccga agcgggcaca     1620

caaccccagg uccaaacaga cgcacagcaa acaagccagu ccccacccuc acccgagcuc     1680

accucggaag agaacaaaau acccgaugcc gacaaagcua acgagaaaaa gguggaccaa     1740

ccacccgaag ccaagaaacc caaaaucaaa gucguuaacg uagaacuacc aauagaagcc     1800

aaucuuguau ggcagcucgg gaaagaccuc cugaauaugu acaucgaaac agaaggcaaa     1860

augaucaugc aggacaaacu cgaaaaagaa cgaaacgaug ccaaaaacgc cgucgaagaa     1920

uacguauacg aguuccgaga caaacuaugc ggccccuacg aaaaguucau cugcgaacaa     1980

gaccaucaaa acuuccuccg acuccucacc gaaacagaag acuggcuaua cgaagaaggc     2040

gaagaccaag ccaagcaggc guacguagac aaacuagagg aacuaaugaa aaucgggacc     2100

ccuguaaaag uacgauucca agaagccgaa gaacgaccaa aaauguuuga agaacuggga     2160

cagcgccucc agcacuacgc caagaucgcc gcagacuucc gcaauaaaga cgaaaaauac     2220

aaccauauag acgaaagcga aaugaaaaag gucgaaaaga gcgucaacga ggucauggaa     2280

uggaugaaca acgucaugaa cgcucaagcc aagaaaaguc uagaccaaga ccccguagug     2340

agggcgcaag aaaucaaaac caaaauaaaa gagcugaaca acacauguga accagucguc     2400

acgcaaccga aaccaaaaau cgaaagcccg aaacucgagc gcacacccaa cggacccaac     2460

aucgacaaga aagaagaaga ccuagaagac aaaaacaacu ucggugccga gcccccgcac     2520

caaaacggug aaugcuaucc caacgagaaa aacagcguga acauggaccu ugacuaa        2577


<210>  1052
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  1052
auggcagaca aagugagacg acaacguccg cgucggcggg uuugcugggc acucguggca       60

guccuccuag cagacuugcu cgcccuaagc gauacccuag cagugauguc uguagacuua      120

ggaucggaau cgaugaaagu agccaucguc aaaccgggag ugccaaugga aaucguacua      180

aacaaagaau cacgcaggaa aacccccgug aucgucacgc ugaaagagaa ugagcgauuc      240

uucggcgauu ccgcagcauc cauggcgauc aaaaacccga aggcaacacu gagauacuuu      300

cagcaccucc ucggaaaaca ggcagacaac ccacacguag cccucuacca agcacgcuuc      360

cccgagcacg aacuaacauu cgacccccaa cgccaaaccg ugcacuucca aaucagcagu      420

cagcuccaau uuagcccaga agagguacuc ggaaugguac ucaacuacuc caggagccuc      480

gcugaagauu uugccgaaca gcccauaaaa gacgcaguca uaacaguacc cgucuucuuc      540

aaccaagccg aaagacgagc gguacuccaa gcagcaagaa uggccggccu caagguccuu      600

caacugauca acgacaacac agcgacagca cucuccuacg gaguauucag aagaaaagac      660

auaaacacca cagcacagaa caucauguuc uacgacaugg gaagcggaag uacuguuugc      720

acaauaguaa ccuaccaaau gguaaagacc aaagaggcag gaaugcaacc acaacuucaa      780

auacgagggg ucggcuuuga caggacucua ggaggacugg agauggaacu ccggcuucga      840

gaacgccuag caggacucuu caacgaacaa cgaaagggcc agagagccaa agacguacga      900

gaaaauccac gagcaauggc caaacuccua agagaagcga accgacucaa aacgguccua      960

agcgcaaacg cggaccacau ggcccaaauc gaaggacuaa uggacgacgu ugacuucaaa     1020

gccaaaguaa cacgaguaga guuugaagaa cucugcgccg accucuucga acgagugcca     1080

ggaccgguac aacaagcacu ccagagcgca gaaauguccc uagacgaaau cgagcaagug     1140

auccuaguag gaggcgcaac ccggguacca cgcguacaag aaguauuacu gaaagcggug     1200

ggaaaagaag aguuagggaa aaacauaaac gccgacgaag ccgcagcaau gggagcagua     1260

uaccaagccg cggcccucag caaagccuuc aaaguaaaac ccuucguagu gcgggacgca     1320

gucguauacc caauacuggu ggaguuuacc agagaagucg aagaggaacc cggcauccac     1380

agccuaaaac acaacaaaag aguccuguuc uccaggaugg gacccuaccc acaacgcaag     1440

gugauaacau ucaaccgaua cagucacgac uuuaacuucc acauaaacua uggggaccug     1500

ggcuuccuag gacccgagga ccuccgcguc uucggauccc aaaaccuaac aaccguaaaa     1560

cucaaaggag uaggagacuc uuucaaaaag uaccccgacu acgaaucaaa ggggauaaaa     1620

gcccacuuua accucgacga aagugggguc cucagccugg accgcguaga gucggucuuc     1680

gaaacacucg ucgaagacag ugccgaagaa gaaucaaccc uaacgaaacu aggcaacaca     1740

auaucaagcc ucuucggagg aggcacaaca ccugacgcca aagaaaacgg aacagacacc     1800

guacaagaag aagaggaaag ccccgcggag ggaucaaaag acgaaccagg cgaacaggug     1860

gaacucaaag aagaagcgga agccccaguc gaggauggaa gccaaccccc accacccgaa     1920

ccgaaaggcg acgcaacacc ggaaggcgaa aaggccaccg agaaagaaaa cggggacaag     1980

ucagaagccc aaaagccaag ugaaaaagcc gaagcaggcc cagaaggagu agccccggcc     2040

ccagaaggag agaaaaagca gaaacccgcc aggaaacgcc gaauggugga ggagauaggc     2100

gucgaacucg uaguacugga ucuaccagac cuccccgaag auaagcuagc acaaagcgug     2160

caaaaacucc aggaccucac ccugcgcgac uuagaaaaac aagagagaga gaaagcagca     2220

aacagccugg aggccuucau cuucgaaaca caagacaagc uguaccagcc cgaauaccaa     2280

gaagugagca cggaagaaca aagagaagag aucuccggca agcuauccgc agccagcacg     2340

uggcucgaag acgaaggagu aggggccaca acaguuaugc ucaaagaaaa auuagcagaa     2400

cuaagaaagc uaugccaagg acuauuuuuc agaguggaag agagaaagaa auggccggaa     2460

aggcucagug cccucgacaa ccuacucaac cauuccagca uguuccugaa gggcgcaagg     2520

cuaauaccag aaauggacca aauauucaca gaaguagaaa ugaccacucu cgagaaagua     2580

auaaacgaga caugggcgug gaaaaacgca acccucgcag aacaagcgaa gcugccagcc     2640

acggagaagc cgguucuacu cagcaaggau auagaagcaa agaugauggc acuagacaga     2700

gaaguccagu accuguuaaa caaagcaaaa uucacaaaac cacgcccaag gccgaaagac     2760

aaaaacggaa cacgagcaga accaccacug aacgcgucag cuucagacca aggagaaaaa     2820

guaauacccc cagcagggca aaccgaggac gcagaaccaa ucagugaacc agagaaaguu     2880

gagacgggaa gcgaaccagg agacacggaa cccuuagaau uaggaggccc aggcgcagaa     2940

ccagaacaaa aagagcaaag cacuggccaa aagcgucccc ucaaaaacga cgagcuauga     3000


<210>  1053
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  1053
augcccgaag agacgcaaac gcaagaucaa ccgauggagg aggaagaagu ggaaaccuuc       60

gcguuccagg cagaaaucgc gcaacugaug agccucauaa ucaacacguu uuacagcaac      120

aaagaaauau uccugcgcga gcuaauaagc aacagcagcg acgcacucga caagauacgu      180

uacgaauccc uaacggaccc gagcaaacua gacagcggga aggaacuaca caucaaccuc      240

auccccaaca agcaggaccg aacccugacc auagucgaca ccggaauagg gaugacgaaa      300

gcagaccuca ucaacaaccu cggaacgauc gccaaaagcg gcacgaaggc uuucauggaa      360

gcacuacaag cgggcgccga cauaaguaug auaggccaau ucggaguagg auucuacagu      420

gccuaccuag uggcagagaa agucaccgua auaacaaaac acaacgacga cgaacaauac      480

gccugggaaa gcagcgccgg gggcuccuuu acaguaagaa cagacaccgg agaaccaaug      540

ggccgcggaa caaaaguaau acuccaccua aaagaggacc aaacagaaua ccucgaggaa      600

agacgaauaa aggagaucgu caaaaagcac agccaauuca uaggauaccc aauaacgcua      660

uucguggaaa aagaacgaga caaagaagug ucagacgacg aagcggagga aaaagaggau      720

aaggaagaag agaaagagaa agaagaaaaa gaaagcgaag acaagccaga aaucgaggac      780

guagggucgg acgaagagga ggaaaagaaa gacggcgaua agaaaaagaa aaagaaaauc      840

aaagaaaagu acaucgacca agaggagcua aacaaaacaa aaccgaucug gacacgaaac      900

ccagacgaca ucacgaacga ggaauacggc gaguucuaca aaucacucac aaacgacugg      960

gaagaccauc uagcaguaaa gcacuucagc gucgaaggcc aacuggaguu cagagcucuc     1020

cuguucguac ccaggcgcgc ccccuucgac cucuucgaaa acagaaagaa gaaaaacaac     1080

auaaaauuau acguaagacg aguauucaua auggacaacu gcgaagaacu gaucccggaa     1140

uaccucaauu ucauccgcgg agucguagac agcgaggacc uaccacuaaa cauaagcaga     1200

gagaugcuac agcagaguaa aauccuaaaa guaauacgga aaaaccuugu caaaaagugc     1260

cuggagcuau ucaccgaacu ugcagaggac aaagaaaacu acaagaaguu cuacgagcag     1320

uucagcaaga auauaaaacu aggcauacac gaagacucac agaaccgcaa gaaacuaagc     1380

gaacuccuga gauacuacac cagcgccagc ggggacgaga uggucagccu aaaagacuac     1440

ugcacaagaa ugaaagaaaa ccaaaaacac aucuacuaua ucacgggaga aacaaaagac     1500

caggucgcga acucagccuu cgucgagcga cuccgcaaac acgggcucga aguaaucuau     1560

augauagagc ccauugacga guacugcgua cagcaacuaa aagaguucga aggaaaaacc     1620

cucguaagcg ucacgaaaga aggccuagaa cugcccgaag acgaagagga gaaaaagaaa     1680

caagaagaaa agaaaacaaa auucgaaaac cugugcaaaa ucaugaaaga cauccuggag     1740

aagaaagugg agaaaguagu cguaagcaac cgccuaguaa cgagcccaug cugcauaguc     1800

acaagcacau acggauggac ggcgaacaug gagcgaauaa ugaaagccca agcccugcga     1860

gacaacagca caaugggaua cauggcggcc aaaaagcacc uagaaaucaa ccccgaccac     1920

uccaucaucg aaacacucag acaaaaagcc gaagccgaca aaaacgacaa aagcguaaag     1980

gaccugguga uacuccuuua cgaaaccgcc cugcucucaa gcggcuucuc ccuggaggac     2040

ccacagaccc acgcgaacag aaucuacaga augauaaagc ugggccuagg aauagacgaa     2100

gacgacccaa cagccgacga cacauccgca gccgucaccg aagaaaugcc accccuagaa     2160

ggggacgacg acacaagcag aauggaagaa guagacuaa                            2199


<210>  1054
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  1054
auggacucau caaaacuaga cuccggcaaa ggccuacaca uaaaccucgu ccccaacaaa       60

caaaaccaaa cccucaccau cguagacaca cgcaucggca ugaccaaaac cgaccucauc      120

aacaaccucg gaaccgucac caaauccggc acaaaagccu ucauggaagc ccuccaagca      180

gacgcagaca uauccaugau cggccacuuc ggaguaggcu ucuacuccgc cuaccucguc      240

gccaaaaaag ucaccgucau cucaaaacac aacaacgacg aacaauacac cugggaaucc      300

uccgcaggag gcagcuucac cguccgcacc gacgaauaa                             339


<210>  1055
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  1055
augcccgagg aaguacacca cggagaagag gaagucgaaa ccuucgccuu ccaagcggaa       60

aucgcccaac uaaugagcuu gauaauaaac acguucuacu ccaacaaaga gauauuccug      120

cgggagcuaa uaucgaacgc cagcgacgcc cuagacaaga ucagguacga gucccucacc      180

gaccccagca aacuagacuc gggcaaggaa cugaaaaucg acauaauccc gaacccgcaa      240

gagcgcaccc ucacccuagu ggacacggga auaggcauga ccaaagcaga ccucauaaac      300

aaccucggca ccauagccaa gagcggaacc aaggccuuca uggaagcacu gcaagcagga      360

gcagacauaa guaugaucgg gcaauuuggc guaggguucu acucagcgua ccucgucgcc      420

gaaaaaguag uagucauaac gaaacacaac gacgacgagc aauacgcgug ggagucaagc      480

gcaggaggga gcuucaccgu acgggcagac cauggcgaac ccauaggcag aggcaccaaa      540

guaauccucc accuaaagga agaccaaaca gaguaccuag aagaacggag aguaaaagaa      600

gucgucaaga aacacuccca auucauaggc uaucccauca cacuauaccu cgagaaagaa      660

cgagaaaaag aaauauccga cgacgaagcc gaagaagaaa aaggggaaaa agaagaggaa      720

gacaaagacg acgaagaaaa gcccaaaaua gaagacguug gcucggacga ggaggacgac      780

agcggcaaag acaagaaaaa gaaaacgaag aaaauaaaag agaaauacau cgaucaagaa      840

gaacucaaca aaaccaaacc gaucuggaca cggaaccccg acgauaucac gcaagaggag      900

uacggcgagu ucuacaaauc acuaacgaac gacugggaag accaccucgc ggucaagcac      960

uucagugugg aaggccaacu agaguuccga gcgcuauugu ucaucccaag acgcgcaccc     1020

uucgaccucu ucgaaaacaa aaagaagaaa aauaacauaa aacuguacgu acgacgggug     1080

uucaucaugg acagcugcga cgaauugaua ccggaauacc ugaacuucau ccgaggaguc     1140

guggacucag aagaccuccc acuaaacauc ucccgagaaa ugcuucaaca gagcaaaauc     1200

cuaaaaguga ucaggaaaaa caucguaaag aaaugcuuag aacuauucag cgaacuagca     1260

gaggacaaag aaaacuacaa gaaauucuac gaagccuuca gcaaaaacuu gaaacuaggc     1320

auacacgaag acagcacgaa ccgaaggcgc uuguccgaac uacuacgcua ccacacgucc     1380

cagagcggcg acgagaugac cagccugagu gaauacguga gccgcaugaa agaaacgcag     1440

aaaagcauau acuacauaac aggcgaaagc aaagaacaag uagcgaacag ugccuuuguc     1500

gaaagaguac gaaaacgcgg auucgagguc guauacauga cggaaccaau agaugaguac     1560

ugcguccaac aacuaaaaga guucgacggg aaaagccuag ucaguguuac gaaagagggc     1620

cucgaacuac ccgaagacga ggaggagaaa aagaaaaugg aagaaagcaa agcaaaauuc     1680

gaaaaccugu gcaagcucau gaaagaaaua uuggacaaga aagucgaaaa aguaacgauc     1740

ucgaaucgac ucguaucauc ccccugcugc auagucacga gcacauacgg auggacagcg     1800

aauauggagc ggaucaugaa ggcacaagcc cuacgcgaca acagcaccau gggcuacaug     1860

auggcgaaga aacaccucga gauaaaccca gaccacccga ucguggagac gcuaagacag     1920

aaagcagaag ccgacaaaaa cgacaaagcc guaaaagacc uaguaguacu gcuauucgaa     1980

acagcccugc ucagcagcgg auucucacuc gaagacccgc aaacccacag caaccgaauc     2040

uaccgcauga ucaagcucgg acucggcauc gacgaagacg aaguagccgc cgaagaaccg     2100

aacgcagccg ucccugacga gauaccgccc cucgaaggcg acgaggacgc aagccgaaug     2160

gaggaaguag acuaa                                                      2175


<210>  1056
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  1056
augcgagccu uauggguccu cggacucugc ugcgugcuac ugaccuucgg cagcguaaga       60

gcagacgacg aggucgacgu agacggcacg guagaggaag accucggcaa aucgcgagaa      120

ggcucacgca cagacgacga aguaguccag cgagaagaag aagcgauaca acuugacggg      180

cugaacgcga gccagauccg cgaacucagg gagaaaagug aaaaauucgc auuucaggca      240

gaaguuaaca ggaugaugaa gcuaaucaua aauucccugu acaaaaacaa agagaucuuc      300

cuacgggaac uaauaucaaa cgccagcgac gcucuagaca aaaucagacu aauaagccua      360

acagacgaaa acgcacuaag cggaaacgaa gaauugacag ucaaaaucaa gugcgacaaa      420

gagaaaaacc ugcugcacgu caccgacaca ggcgugggca ugacccgaga ggaacucguc      480

aaaaaccugg gaacgauagc aaagucaggg accagcgagu uccucaacaa aaugacagaa      540

gcccaggagg acgggcagag cacgagcgaa cugauagggc aauucggagu aggauucuac      600

agcgcguucc ugguagcgga caaagucaua gucaccagca aacacaacaa cgauacccag      660

cacaucuggg agagcgacag uaacgaauuu agcguaaucg cagacccucg aggcaacaca      720

cuagggcgag ggaccacaau aacacuggua cuaaaggaag aagccaguga cuaccucgag      780

cuagauacca ucaagaaucu cguaaagaaa uacucacaau ucaucaacuu cccaaucuac      840

gucuggagca gcaaaacaga aacgguugaa gaaccuaugg aggaagagga agcggcaaaa      900

gaggaaaagg aagaaucaga cgacgaggcc gccguggaag aggaagaaga ggaaaagaaa      960

ccaaaaacga agaaagugga gaaaacagua ugggacuggg aacugaugaa cgacaucaag     1020

cccauauggc aaagaccaag caaggaagua gaagaagacg aguacaaggc guucuacaaa     1080

aguuucucca aggagucaga cgaccccaug gcauauauac acuucacggc agagggcgaa     1140

gucacauuca agagcauacu cuucgugccc accucggcac cacgcggacu auucgaugag     1200

uacgggagca agaaaagcga cuacauaaaa cuauacguca ggaggguauu cauaacggac     1260

gacuuccacg acaugaugcc caaguaccug aacuucguca agggaguagu cgauagcgau     1320

gaccuacccc ugaacguaag cagggaaacc cuacaacaac acaaacuucu caaaguaauc     1380

cggaaaaagc ucgugaggaa gacccuagac augauaaaga aaauagcgga cgacaaauac     1440

aacgacacau ucuggaaaga guucgggaca aacauaaaac uaggugugau agaggaccac     1500

agcaacagga cgagacuggc caaacuccua cgauuccaau caagccauca ccccacagac     1560

aucacgagcc uagaccagua cguagaaaga augaaggaaa aacaggacaa aauuuacuuc     1620

auggcagggu ccagcagaaa agaggccgaa agcucccccu ucgucgaaag gcugcucaag     1680

aaaggguaug aagucauaua ccuaacagag ccagucgaug aauacugcau acaggcacug     1740

ccagaguuug acggcaagag auuccaaaac gucgcaaaag aaggagugaa auucgacgaa     1800

agugagaaga ccaaagagag cagagaagcc gucgagaaag aguucgaacc ucuccucaac     1860

uggaugaaag acaaagcgcu aaaagacaag auagaaaaag cagucguaag ccaacgacuc     1920

acagaaagcc caugcgcgcu agucgccucg caauacggau ggucagggaa cauggaaaga     1980

aucaugaaag cgcaagcgua ccaaacuggg aaagacauau ccacgaacua cuacgccagc     2040

caaaagaaaa cguucgaaau caaccccagg cauccacuga uaagggauau gcuacgcaga     2100

auaaaagaag acgaggacga caaaacaguc cucgaccucg cagucguccu cuucgaaacg     2160

gcaacccuua gaagcggcua ccugcugcca gacaccaaag ccuacggaga caggaucgag     2220

cgaaugcuac gacucucacu aaacauagac ccggacgcaa aaguagagga agaaccggag     2280

gaggagccag aagaaacagc cgaagauaca acagaggaca cggaacaaga cgaagacgaa     2340

gaaauggacg uagguacaga cgaggaagaa gaaacagcca aagagagcac agcggagaag     2400

gacgagcuau ag                                                         2412


<210>  1057
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  1057
auggcccgag aauuaagagc ccuauuacuc uggggacguc gucuccgucc ccuccuccgc       60

gcaccagccc uagcagccgu acccggcggc aaacccauuc ucugcccaag aagaaccacu      120

gcccagcuag ggccccgacg aaaccccgcg uggucgcucc aagcuggacg acucuucuca      180

acccaaaccg cagaagacaa agaagaaccc cuccacagca ucauaucuuc aacagaaucc      240

guccaaggua gcacauccaa acacgaguuc caagccgaaa ccaagaaacu guuagauauc      300

gucgcccgcu cccucuacag cgaaaaagaa gucuucaucc gcgaacugau cucaaacgcc      360

agcgacgccc uagagaaacu acgccauaag cuagucucag acggccaagc acuacccgaa      420

auggaaauuc accuccaaac caacgccgaa aaaggcacca uaacaaucca agacaccgga      480

aucggcauga cccaagagga acucguaagc aaccucggca cuaucgcgcg cucaggguca      540

aaagcauucc uagacgcuuu acaaaaccag gccgaggcuu cauccaaaau aaucggccaa      600

uucggcguag gcuucuacuc agccuucaug gucgcggauc gcgucgaagu cuacucccgc      660

agcgcagccc cagggagccu aggguaccag uggcucagcg acggcuccgg cguauucgaa      720

aucgccgaag ccuccggagu cagaacagga accaaaauca uaauucaccu gaaaucugac      780

ugcaaagagu ucagcuccga agcacgcguu cgagacguag ucacaaaaua cuccaacuuc      840

gucuccuucc cacucuaccu caacggaaga cgcaugaaca cccuccaggc caucuggaug      900

auggacccca aggacguccg ugaauggcaa cacgaagagu ucuaccgaua cguggcacaa      960

gcccacgaua aaccacguua cacccuacac uacaaaaccg acgccccacu caacaucaga     1020

agcaucuuuu acguccccga caugaaaccg ucaauguucg acgucucccg ugaacuagga     1080

uccuccgucg cacucuacuc acgcaaaguc cuaauccaaa cuaaagccac agacauccuu     1140

cccaaauggc uccgguucau acgcggcguc guggacucag aagacauccc ccuaaaccuc     1200

ucccgcgaac uacuccaaga auccgcgcua auccgaaaac uuagagacgu acuacaacaa     1260

cggcuaauca aauucuucau cgaccagagu aagaaagacg ccgaaaaaua cgcuaaauuc     1320

uucgaagacu acggacuauu caugcgagaa ggcaucguca ccgccaccga acaagaaguc     1380

aaagaagaua ucgcaaaacu ccuacgcuac gagucuuccg cccuacccuc aggacaacuu     1440

accucacuaa gcgaauacgc cagccgcaug cgcgcgggca cacggaauau auacuaccua     1500

ugcgcaccca accgacaucu cgccgaacac agcccauacu augaagccau gaagaagaaa     1560

gacacugaag uccuauucug cuucgaacaa uuugaugagc ucacccuacu acaccuccgg     1620

gaauuugaca aaaagaaacu aauauccguc gagaccgaca ucgucguaga ccacuacaaa     1680

gaggaaaaau ucgaggaccg cuccccagca gccgagugcc uaagcgaaaa agaaaccgaa     1740

gaacuaaugg ccuggaugcg caacguucua ggcucaagag uaaccaacgu aaaaguaacc     1800

cuacgacucg acacccaccc cgccauggua accguacucg aaaugggagc agcccgccac     1860

uuccuacgaa ugcaacaacu cgccaaaaca caggaggaac gagcccagcu ccuacagcca     1920

acacucgaaa ucaacccccg acacgcacuc aucaagaaac ucaaccaacu ccgggcaucc     1980

gaaccaggac ucgcccagcu ccuaguagac cagaucuaug aaaacgccau gaucgcugca     2040

ggccuagucg acgacccaag agcaaugguu ggacgacuaa acgaacugcu cgucaaagcc     2100

cucgagcgcc acuaa                                                      2115


<210>  1058
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  1058
augggcaaaa ucuccucccu acccacccaa cuauucaaau gcugcuucug cgacuuccua       60

aaagucaaaa ugcacacaau guccucaucc cacuuauucu accucgcacu cugccuccuc      120

acauucaccu cauccgccac cgcaggcccc gaaacccuau gcggcgccga acucgucgac      180

gcacuccaau ucgucugcgg cgaccgcggc uucuacuuca acaaacccac aggcuacggc      240

uccuccucaa gacgagcacc ccaaaccggc aucguagacg aaugcuguuu ccgaucaugc      300

gaccuucgcc gccucgaaau guacugcgca ccccucaaac ccgccaaauc agcccgcucc      360

guccgugccc aacgacacac cgacaugccc aaaacccaaa aagaagucca ccucaaaaac      420

gccucccgcg gcuccgcagg caacaaaaac uaccgcaugu aa                         462


<210>  1059
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  1059
augggaaucc ccaugggcaa aucaaugcuc guccuccuca ccuuccucgc cuucgccucc       60

ugcugcauag ccgccuaccg acccuccgaa acacucugcg gcggagaacu cgucgacacc      120

cuacaauucg ucugcggcga ccgaggcuuc uacuucuccc gacccgccuc acgaguaucc      180

cgccgcuccc gcggcaucgu cgaagaaugc ugcuuccgcu caugcgaccu cgcccuccuc      240

gaaaccuacu gcgccacccc agccaaaucc gaacgagacg ucuccacccc acccacagua      300

cuucccgaca acuuuccccg auaccccgua ggcaaauucu uccaauacga caccuggaaa      360

caaucaaccc aacgacuccg ccguggccuc cccgcccuac uccgcgcacg ccgcggacac      420

guccuagcaa aagaacucga agccuuccgc gaagccaaac gacaccgccc ccucaucgcc      480

cuccccaccc aagaccccgc ccacggaggc gccccacccg aaauggccuc caaccguaaa      540

uaa                                                                    543


<210>  1060
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  1060
augaacuccu ucuccaccuc cgccuucggc cccgucgccu ucucccucgg ccuccuccuc       60

guccuccccg ccgccuuccc cgcccccguc ccccccggcg aagacuccaa agacgucgcu      120

gccccccacc gccaaccccu aaccuccucc gaacgcaucg acaaacaaau ccgcuacauc      180

cuagacggca ucucugcacu ccgaaaagaa accugcaaca aaucuaacau gugcgaaucc      240

uccaaagaag cccuagccga aaacaaccuc aacuuaccca aaauggccga aaaagacggc      300

ugcuuccaau ccggcuucaa cgaagaaacc ugccucguca aaaucaucac cggccuccuc      360

gaauucgaag ucuaccucga auaccuacaa aaccgauucg aauccucaga agaacaagcc      420

cgagccgucc aaauguccac caaaguccuc auccaauucc uccaaaaaaa agccaaaaac      480

cucgacgcca ucaccacacc ugacccaacc accaacgccu cacuccucac aaaacuccaa      540

gcccaaaacc aauggcucca agacaugaca acacaccuca uccuccgcuc cuucaaagaa      600

uuccuucaau ccucccucag agcccuccgc caaauguaa                             639


<210>  1061
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  1061
augccccuac ucuggcuacg cggcuuccua cuagcaagcu gcuggaucau aguaagaagc       60

ucacccaccc caggaagcga aggacacagc gccgcgccag acugcccauc augcgcacuc      120

gccgcccucc ccaaagacgu acccaacagc cagcccgaaa ugguagaagc agugaaaaaa      180

cacauacuaa acaugcucca ccuaaaaaag cgacccgacg uaacccaacc cgucccaaaa      240

gcagcacuac uaaacgcaau cagaaaacuc cacguaggga aagucggcga aaacggauac      300

guagaaaucg aagacgacau aggaaggcgc gccgaaauga acgaacucau ggaacaaacg      360

ucggaaauaa ucacauucgc agaaucaggu acggccagaa aaacccuaca cuuugagauc      420

agcaaagaag ggagcgaccu aagcgucguc gaaagagcag aggucuggcu guuccucaaa      480

guuccaaaag ccaacagaac acgcacaaaa guaacaauac gccuauucca gcaacaaaaa      540

cacccacaag gcagccuaga caccggagaa gaggccgagg aaguaggacu aaaaggagaa      600

cggagcgaac uacuacuaag cgaaaaaguc guagacgccc gcaaaagcac auggcaugua      660

uuccccguaa gcagcuccau acaacgacuc cuagaccaag gcaaaucauc acucgacgua      720

agaaucgcgu gcgaacaaug ccaagaaagc ggagccagcc uuguacuacu gggcaagaaa      780

aaaaaaaaag aagaggaagg cgaagggaaa aaaaaaggcg gcggagaagg aggcgccgga      840

gcagacgaag aaaaagaaca aagccacaga cccuuccuaa ugcugcaagc acgacagagc      900

gaagaccacc cccaccgcag acgccgacgc ggacucgaau gcgacggaaa aguaaacauc      960

ugcugcaaga aacaauucuu cgucagcuuc aaggacauag gauggaacga cuggauaaua     1020

gcaccgagcg gcuaccaugc aaacuacugc gaaggcgaau gcccaagcca caucgcaggc     1080

acaagcggaa gcagccuaag cuuccacagc accgucauca accacuacag aaugcgagga     1140

cacagcccau ucgccaaccu gaaaagcugc ugcgucccga cgaaacuaag accaaugagc     1200

augcuauacu acgacgacgg ccaaaacaua auaaagaaag acauacaaaa caugauagua     1260

gaagagugcg gcugcagcua a                                               1281


<210>  1062
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  1062
auggacggcc uccccggccg agcacuaggc gccgcaugcc uccuccuacu cgcagccgga       60

uggcuuggcc ccgaagcaug gggcucccca acaccaccuc ccacccccgc agcaccaccc      120

ccacccccac cacccggcuc ccccggcggc agccaggaca caugcaccuc augcggcggc      180

uuccgacgcc ccgaagaacu cggccgcguc gacggagacu uccucgaagc cguaaaacgc      240

cacauccuuu cccgccucca aaugcgaggc cgacccaaca ucacucaugc cguccccaaa      300

gccgccaugg ucaccgcccu acgcaaacuc cacgccggca aaguccgaga agacggccgc      360

gucgaaaucc cccaccucga cggccacgcc agccccggcg ccgacggcca agaacgaguu      420

uccgaaauca ucuccuucgc cgaaaccgac ggccuugcau ccagccgagu acgccucuac      480

uucuucaucu caaacgaagg caaccaaaac cucuucguag uacaagccuc ccuuuggcuc      540

uaucucaaac uccuacccua cguacuagaa aaaggcucuc gccgcaaagu aagagucaaa      600

gucuacuucc aagaacaagg ccacggcgac cgauggaaca uggucgagaa acgcgucgac      660

cuaaaacgcu ccgguuggca cacauucccc cucaccgaag caauccaagc ccucuucgaa      720

cgaggggaac gccgccucaa ccuagauguc caaugcgaca gcugccaaga acuagccguc      780

guccccgucu ucgucgaccc cggcgaggaa ucccaccgac ccuucgucgu cguccaagca      840

cgacucggcg acucucgcca cagaauacgu aaacgaggac ucgaaugcga cggccgcacc      900

aaccucugcu gcagacaaca auucuucauc gacuuccgcc ucauuggaug gaacgacugg      960

aucauagcac ccacuggaua cuacggcaac uacugcgaag gcuccugccc cgcauaccuc     1020

gcaggagucc ccggaagcgc auccucuuuc cacaccgcag uagugaacca auaccgcaug     1080

cgcggccuca accccggaac cgucaacagc ugcugcaucc ccaccaaacu uuccaccaug     1140

agcaugcucu acuucgacga cgaauacaac aucguaaaac gagacguccc caacaugaua     1200

guagaagaau gcggaugcgc auaa                                            1224


<210>  1063
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  1063
auggcacuaa ggguacuccu ccucaccgcc cucacacucu gccacggauu caaccucgac       60

acugaaaacg caaugacauu ccaagaaaac gcgcggggcu ucggacaauc agugguccag      120

cugcaaggua gccgcgucgu cgugggcgcc ccgcaagaga ucguagcagc caaccagcgc      180

ggcucucuau aucaaugcga cuacucaacu ggcaguugcg aacccaucag acuacaaguc      240

ccagucgaag cugucaacau gagccuugga cuaucgcuag ccgcaacaac cucgccuccu      300

caacuccucg ccugcggccc aaccguccac cagaccugcu ccgagaauac cuacgucaaa      360

ggccucugcu uuuuguucgg cucuaaccug cgccaacaac cgcaaaaauu cccggaagcc      420

cugcgaggcu gcccccagga agacucagac auagcuuucc uaauugacgg guccggcucc      480

aucauacccc acgacuuccg ucgaaugaaa gaguucguau caacuguaau ggaacaacuc      540

aagaaaucua aaacgcuguu cucacucaug caauacagcg aagaguucag gauccacuuc      600

accuucaaag aguuccaaaa caacccaaac ccacgcucgc ucgucaagcc aauaacccaa      660

cuccucggca gaacccauac agcuacaggc auccgaaaag ucgucagaga acucuucaac      720

aucaccaacg gcgcccggaa aaaugccuuc aaaauccuug uagucaucac cgacggugaa      780

aaauucggcg auccucuugg auacgaagac guaauuccug aagccgacag agaaggagug      840

auucgauacg ucaucggagu gggcgacgca uuccgcagug aaaagucccg acaagaacug      900

aacaccaucg ccuccaaacc uccccgagac cacguuuucc aaguaaacaa cuucgaagca      960

cucaagacca uccaaaacca acugcgcgag aaaauauucg caaucgaagg cacgcaaacc     1020

ggguccaguu cauccuucga acacgaaaug ucccaggaag gauuuuccgc agcgaucacu     1080

uccaacggac ccuuacuauc cacagucggc ucguacgacu gggccggcgg cguauuccua     1140

uacaccagca aagaaaaauc caccuucauc aacaugaccc gggucgacag cgacaugaac     1200

gaugccuacc ucggguaugc agccgcaauu auacuaagga accgcguuca aucccucgua     1260

cugggagcac cccgcuacca gcacauaggc cuaguggcua uguuccguca aaacacaggc     1320

augugggaau ccaaugccaa cguuaagggc acgcaaauag gagccuacuu cggcgccucu     1380

cuaugcuccg uagacguaga cuccaacgga uccacagacc uaguacugau cggcgcaccc     1440

cacuacuacg aacaaaccag aggcggacaa gucucagugu guccacuccc ccgcggucga     1500

gcacgauggc aaugugaugc cguccuauac ggcgaacagg gacaaccgug gggccgcuuu     1560

ggagcugccc ucaccguccu cggcgaugua aacggugaca aacucacuga uguagccaua     1620

ggcgcccccg gagaagagga uaacagagga gccgucuacc uauuccacgg caccucagga     1680

agcgggauca gcccauccca cucccaacgc auagcgggcu caaagcuauc gccucgccug     1740

caguacuuug gccaaagccu cuccggcggc caagaccuca ccauggacgg ucuaguagac     1800

cucacaguag gagcccaagg acauguacuc cuccuucgcu cgcagcccgu acucagagua     1860

aaggccauca uggaauuuaa uccaagagaa gucgcccgaa acguauucga augcaacgau     1920

caggugguua aagguaaaga agccggugag guacgcguau gucuccacgu acaaaaaucg     1980

acccgggaca gacuucgcga aggacaaauc caaucaguag ucaccuacga ccucgcucua     2040

gacuccgguc guccccauuc acgagccgug uucaacgaaa ccaaaaacuc uacaagacgc     2100

caaacucagg uacucggcuu gacacaaacu ugugagaccu uaaaacuuca gcugccaaac     2160

uguaucgagg accccgucuc cccaaucgua cugcggcuua acuucucucu cgucggcaca     2220

ccccuuuccg cguucgguaa ccugagaccc guccucgcag aagacgccca acgacucuuc     2280

accgcacucu uccccuuuga gaaaaacugc ggcaacgaca acaucugcca agaugacuua     2340

agcauuacau ucucauuuau gagccuagac ugucucguag uaggcggacc ccgggaauuu     2400

aacgucacug uaaccgugcg caacgacggu gaagacuccu acaggacgca agucacauuc     2460

uucuuccccc ucgacuuaag cuaccguaaa gucagcaccc uucagaacca gcguucucaa     2520

cgauccugga ggcuugcgug cgaaucagcu agcucaaccg aggucuccgg cgcgcucaaa     2580

uccaccucau gcuccaucaa ccaccccauc uuccccgaaa acagcgaagu uaccuucaac     2640

auaaccuucg acguagacuc caaggcauca cuaggaaaca aacuccuccu caaggccaac     2700

guaaccuccg agaauaacau gccacgcacg aauaaaacag aguuccaauu ggaacucccc     2760

guaaaauacg cgguauacau ggucgucacu ucucacggag uaucuaccaa auaccuaaac     2820

uuuacagccu ccgaaaacac aagccgagua augcagcauc aauaccaagu gucaaaccug     2880

ggacaaagau cgcuaccuau cucacucguc uuccugguac cggucaggcu uaaccaaacg     2940

gucauauggg accgccccca aguaaccuuu ucagaaaacc ucuccagcac augccacacc     3000

aaagaaaggc ucccaucaca uagcgacuuc cuagcagagc uccgcaaggc gcccgucguu     3060

aacugcucca uagcagugug ccaacgcauc cagugcgaca uaccauucuu uggcauccag     3120

gaggaguuca acgcaacccu caagggaaac cucucuuucg acugguacau aaaaacuucc     3180

cacaaucacc uccuaaucgu cuccaccgca gaaauccucu ucaacgacag cguauucacc     3240

cuacuaccag gccagggagc guucguccgg agccaaaccg aaaccaaagu ggaaccauuu     3300

gaaguaccca accccuuacc ccuaaucguc ggguccucag ucggcggccu acuacuucuc     3360

gcuuuaauca ccgccgcccu cuacaaacua ggcuuuuuca aaagacaaua caaagacaug     3420

auguccgaag gaggcccacc cggggccgaa ccgcaauaa                            3459


<210>  1064
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  1064
auguucagcc ucaaaacgcu ccccuuccuc cuacuccucc acguccaaau aucuaaagcc       60

uuucccgucu ccucuaaaga aaagaacaca aaaacaguac aagacuaccu ggaaaaauuc      120

uaccaacucc cauccaacca auaccaguca acccgcaaaa acggcaccaa cguaaucguc      180

gaaaaacuca aagaaaugca acgcuucuuc ggacucaacg ucacugguaa accaaacgaa      240

gaaacccucg acaugaugaa aaagccgaga ugcggcguac cagacuccgg cggcuuuaug      300

cucacccccg gaaacccgaa augggaacgc accaaccuca ccuaccgcau acgaaacuac      360

acaccccaac ucucugaagc cgaagucgaa cgugccauca aagacgccuu cgaacucugg      420

ucaguagccu ccccacucau uuucacacga aucucccaag gugaagccga caucaacauc      480

gccuucuacc aacgagacca cggcgacaau ucccccuuug acggcccaaa cggaauacua      540

gcccacgccu uccaacccgg ucaaggcauc ggcggcgacg cccacuucga cgcagaagaa      600

accuggacca auaccuccgc aaacuacaac cucuuccucg ucgcagccca cgaauuugga      660

cacucacucg gccucgcaca cucuagcgac cccggcgccc ucauguaccc caacuacgcc      720

uuccgagaaa ccuccaacua cucacucccg caagacgaca ucgauggaau ccaagccauc      780

uacggccucu ccuccaaccc aauccaaccc acuggccccu caacccccaa acccugugac      840

ccaucccuca cauucgacgc cauuaccacc cuccgcgggg aaauccucuu cuucaaagau      900

cgcuacuucu ggcgccgaca cccccaacua caacgcgucg aaaugaauuu caucucccuc      960

uucuggcccu cccucccuac cggcauucaa gccgccuacg aagacuucga ucgcgaccuu     1020

auuuuucucu uuaaaggcaa ccaauacugg gcccucucgg gcuacgacau ccuacaagga     1080

uaccccaaag acaucuccaa cuacggauuc cccucuuccg uccaagcuau agacgccgcc     1140

gucuucuacc gauccaagac auacuucuuc gucaaugacc aauucuggcg auacgacaac     1200

caacgacagu ucauggaacc cggguacccc aaauccauuu ccggagccuu cccaggcauc     1260

gaauccaaag ucgacgccgu cuuccagcaa gaacacuucu uccacgucuu cucaggcccc     1320

cgcuacuacg ccuucgaccu aaucgcccaa cgcgucaccc gcgucgcccg aggcaacaaa     1380

uggcucaacu gcagauacgg auaa                                            1404


<210>  1065
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  1065
augagccugu ggcaaccccu cguccucguc cuucuugucc ucgguugcug uuucgccgca       60

ccccgccaac gacaguccac ccucguccuc uuccccggag accuccgcac aaaccuaacu      120

gaccgccagc ucgccgaaga auaucuuuac cgcuacggcu acacccgcgu cgcagaaaug      180

agaggcgaau ccaaaucucu ggggcccgcc cuccuccucc uccaaaaaca gcucucccuc      240

cccgagaccg gagaacuuga cuccgccacc cucaaagcaa ugcgaacacc acgcugcggc      300

gucccagacc ucggccgcuu ccaaacguuc gaaggcgacc uaaaauggca ucaucacaac      360

auuaccuacu ggauccaaaa cuacuccgaa gaccuccccc gcgccguaau agacgacgcc      420

uucgccagag ccuucgcgcu cugguccgcc gucaccccac uaacauucac ccgcgucuac      480

ucacgcgacg ccgacauagu gauucaauuc ggugucgcug aacacgggga cggcuacccc      540

uucgacggaa aagacggccu acuggcccac gcauucccac ccggacccgg aauccaaggu      600

gacgcccacu uugacgacga cgagcuuugg ucccuaggaa agggcgucgu agucccaaca      660

cgcuucggaa acgcagacgg cgccgcuugc cacuuccccu ucauauucga aggaaggucc      720

uacucagcau gcaccaccga cggccgauca gacggccucc cguggugcuc gaccacagcg      780

aacuacgaca cagaugaccg cuucggcuuc ugccccucag aacgacuaua cacccaggac      840

ggcaacgccg acggaaaacc cugccaauuc ccauucauau uccaggguca gagcuacucc      900

gccuguacga cggacggcag aagcgauggc uaccgcuggu gcgcaaccac agcgaacuac      960

gaccgagaca aacuuuucgg uuucugucca acccgcgcag acuccaccgu aaugggcggc     1020

aacagcgccg gagaacuaug cgucuuccca uucaccuucc ucggaaaaga auacuccacu     1080

uguaccucgg aaggcagagg cgacggaaga cucuggugug cuacaaccuc aaacuucgac     1140

uccgacaaga aauggggcuu cugccccgau caaggcuaca gucuauuccu cgucgcagcc     1200

cacgaguucg gacacgcccu cgggcucgac cacuccuccg uacccgaagc gcuaauguac     1260

ccaauguaca gguuuaccga aggaccaccc cuacacaaag acgacgucaa cggaauccgc     1320

caccuuuacg gcccccgccc cgaacccgaa ccucguccac ccaccacaac aacaccccaa     1380

cccaccgcac cgccaaccgu augucccacg gggcccccua ccguccaccc gagcgaaaga     1440

cccacagcag gcccuaccgg uccacccuca gcaggaccca caggaccccc uacugccggc     1500

cccucuacag ccacuacugu cccccuaagc ccaguugacg acgcaugcaa cguaaacaua     1560

uuugacgcaa ucgccgaaau cggcaaccaa cuuuaccuau ucaaagacgg uaaauacugg     1620

cgauucuccg aaggacgcgg aagucgcccc cagggcccau uccuaaucgc agacaaaugg     1680

ccagcccuac cgagaaaacu agauucaguc uucgaagaaa gacuaagcaa gaaacucuuc     1740

uucuuuucug gccgacaagu auggguauac acaggagcca gcguacuagg ccccagaaga     1800

cucgacaaac uaggccuagg agcagacguu gcacaaguaa ccggagcucu ccguuccggc     1860

agaggcaaaa ugcuauuguu cucuggccgc agacuuuggc gcuucgacgu caaagcucaa     1920

augguagacc cccgauccgc auccgagguc gaccgcaugu uccccggcgu ccccuuagac     1980

acacacgacg uuuuccagua ccgagagaaa gccuacuucu gccaagaccg cuucuacugg     2040

agaguaagca gcagguccga acucaaccaa guagaccaag ucggauacgu aacauacgac     2100

auccuccaau gcccagaaga cuga                                            2124


<210>  1066
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  1066
augcaccccg gaguccucgc cgcauuccua uuccucuccu ggacccacug ccgagcccua       60

ccccucccau ccggcggaga cgaagaugac cucuccgaag aagaccucca auucgcagaa      120

cgcuaccuuc gcuccuacua ccacccaacc aaucucgcag gcauccuaaa agaaaacgcc      180

gcauccucaa ugaccgaacg ccuccgagaa augcaauccu ucuucggccu cgaagucacc      240

ggcaaacucg acgacaacac ccucgacgua augaaaaaac cuagaugcgg agucccagac      300

gucggagaau acaacguauu cccccguacc cugaaauggu caaaaaugaa ccucacguac      360

aggaucguaa acuacacccc cgacaugacc cauagcgaag ucgaaaaagc cuucaaaaaa      420

gccuucaaag ucugguccga cgucacucca cuaaacuuca cccgucucca cgacggcaua      480

gccgacauca ugauauccuu cggaaucaaa gagcacggcg acuucuaccc cuucgacgga      540

cccagcgguc uccucgcaca cgccuucccc ccgggcccca acuacggcgg agacgcccac      600

uucgaugacg acgagaccug gacauccucc ucaaagggcu acaaccucuu ccucgucgcc      660

gcccacgaau ucgggcacuc acuuggacuc gaccauucca aagaccccgg agcccucaug      720

uucccaaucu acacauacac cggcaaaagu cacuucaugc uccccgacga cgacguccaa      780

ggaauucaaa gccucuacgg ccccggcgau gaagacccca accccaaaca ucccaaaaca      840

cccgacaagu gcgacccuuc ccucagccuc gacgcaauca ccucacucag aggcgaaacc      900

augauauuca aagaccgauu cuucuggcga cuccacccgc aacaaguaga cgccgaacua      960

uuccuaacca aauccuucug gccagaacua ccuaaccgaa ucgacgccgc cuacgaacac     1020

cccagccacg accucaucuu caucuuccgc ggcagaaaau ucugggcccu caacggcuac     1080

gacauccucg aaggcuaccc caaaaaaaua ucugaacucg gccucccaaa agaagucaaa     1140

aaaauauccg ccgccgucca cuucgaagac accggcaaaa cccuacucuu uagcggcaac     1200

caagucuggc gauacgacga cacgaaccac aucauggaca aagacuaccc ucgccucauc     1260

gaagaagacu ucccaggaau cggcgauaaa guagacgcgg uuuacgaaaa aaacggcuac     1320

aucuacuucu ucaacggccc aauacaauuc gaauacucca uaugguccaa ccgaauaguc     1380

agagugaugc cagcaaauuc aauccucugg ugcuaa                               1416


<210>  1067
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  1067
auggaaaccc ccaacacaac cgaagacuac gacaccacca cggaguucga cuacggcgac       60

gccacccccu gccaaaaggu aaacgaacga gccuucggcg cacaacuucu cccaccccug      120

uacucccuag uguucguaau aggccucguc ggcaauaucc uagucguauu aguccucguc      180

caauacaaac gccucaagaa caugaccucu auauaccuac ucaaccuagc aaucuccgac      240

cuccuuuucc uguucacccu ccccuucugg aucgacuaua aacucaaaga cgauuggguc      300

uucggagacg ccaugugcaa aauccucucc ggcuucuauu auaccggucu cuacuccgaa      360

aucuucuuca uaauccuccu caccaucgac agauaucucg ccauagucca cgccgucuuu      420

gcacuccgcg cccgcaccgu caccuucggu gucaucaccu ccaucauaau cugggccuua      480

gccauccucg ccuccaugcc cggacucuac uuuuccaaaa cccaauggga guucacccac      540

cauaccugcu cccuccacuu cccccacgaa ucccuacgcg aauggaaacu cuuccaagca      600

cuaaaacuaa accucuuugg ccucguccuu ccccuccuag ucaugaucau cugcuacaca      660

ggcaucauca aaauccuacu ucgucgcccu aaugaaaaga aauccaaagc cguccgacuc      720

aucuucguca ucaugauaau cuuuuuccuc uucuggacac ccuauaaucu caccauccuc      780

aucucugucu uccaagacuu ccucuucaca cacgaaugcg aacaaucccg ccaccuagac      840

cucgccgucc aagucaccga agucaucgca uacacccacu gcugcgucaa ccccgucaua      900

uacgcauucg ucggcgaacg cuuccgcaag uaccuccgcc aacucuucca ccgacgcguc      960

gcaguccauc ucgucaaaug guuacccuuu cucucugucg accgccucga acgcguaucc     1020

ucaacaucac ccuccaccgg cgaacaugaa cuuucagccg gcuucuaa                  1068


<210>  1068
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  1068
augcgaaccc ucgccugccu ccuccuccuc ggcugcggcu accucgccca cguacucgcc       60

gaagaagcag aaaucccccg cgaagucauc gaacgccucg cacgcuccca aauccacucc      120

auccgugacc uccaacgacu ccuggaaauc gacuccgucg gauccgaaga cucccuagac      180

accucccuaa gagcccacgg cguacacgcc acaaaacacg uccccgaaaa acgaccccuc      240

cccauccgca gaaaacgauc cauagaagaa gccguccccg ccguaugcaa aacacgcaca      300

gucaucuacg aaauaccccg cucccaaguc gacccaaccu ccgccaacuu ccuaaucugg      360

ccccccugcg ucgaagucaa acgcugcacc ggcugcugca acaccuccuc agucaaaugc      420

caacccagcc gcguccacca ccgcagcguc aaagucgcaa aagucgaaua cguacgcaaa      480

aaacccaaac ucaaagaagu ccaagucaga cucgaagaac accuagaaug cgcaugcgcc      540

accaccagcc uaaacccaga cuaccgcgaa gaagacaccg gccgaccccg cgaauccggc      600

aaaaaacgca aacgcaaaag acuaaaaccc accuaa                                636


<210>  1069
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  1069
augaaccgcu gcugggcccu auuccuaagc cuaugcugcu accuccgccu agucucggcc       60

gagggcgacc ccauccccga agaacucuac gaaaugcuca gcgaucacuc aauccgcucc      120

uucgacgacc uccaacgccu ccuccacggc gaccccggcg aagaagacgg agccgaacua      180

gaccucaaca ugacacgcuc acacuccgga ggggaacucg aaucccucgc acgcggccgc      240

cgcagccuag gcucacuaac aaucgccgaa ccagcaauga ucgccgaaug caaaacaaga      300

acagaagucu ucgaaaucuc acgccgccua aucgaccgca ccaacgccaa cuuccuaguc      360

uggccacccu gcgucgaagu ccaaagaugc uccggaugcu gcaacaacag aaacguccaa      420

ugccgcccca cccaagucca acuccgacca guacaaguaa gaaaaauaga aaucguccgc      480

aaaaaaccca ucuucaaaaa agcaaccgua acccucgaag accaccucgc augcaaaugc      540

gaaaccgucg ccgcagcccg ccccgucacc cgcagccccg gcggaagcca agaacaacga      600

gcaaaaacac cccaaaccag agucaccauc cgaacagucc gcguacgcag accccccaaa      660

ggaaaacacc gcaaauucaa acacacacac gacaaaaccg cccuaaaaga aacccuaggc      720

gccuaa                                                                 726


<210>  1070
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  1070
augucccucu ucggccuacu ccuccuaaca ucugcacucg ccggccaacg ccaaggcacc       60

caagccgaau ccaaccucag cucuaaauuc caauucuccu caaacaaaga acaaaacggc      120

guccaagacc cccaacacga acgcauaauc acagucucaa ccaacggcuc cauccauuca      180

ccccguuucc cccacaccua cccccgcaac accguccuag uauggcgccu aguagcagua      240

gaggaaaacg ucuggaucca acucaccuuc gacgaacgcu uuggacucga agauccagaa      300

gacgauaucu gcaaauacga cuucgucgaa guagaagaac cuuccgacgg cacaauccua      360

ggccgauggu gcggcuccgg caccguccca ggcaaacaaa uauccaaagg caaccaaauc      420

cgcauccgcu ucgucuccga cgaauacuuc cccuccgaac ccggcuucug cauccacuac      480

aacaucguca ugccccaauu caccgaagcc gucucccccu ccguccuccc acccuccgca      540

cucccccuag accugcucaa caacgccauc accgccuucu caacccucga ggaccucaua      600

cgcuaccuag agcccgaacg cuggcaacuc gaccucgaag accucuaccg cccaacaugg      660

caacuccucg gcaaagccuu cgucuucggc cgcaaauccc gcguagucga ccuaaaccua      720

cuaaccgaag aaguacgccu cuacagcugc acaccacgca acuucucagu cuccauccgc      780

gaagaacuca aacgcaccga caccaucuuc uggccaggcu gccuccuagu aaaacgcugc      840

ggcgggaacu gcgccugcug ccuccacaac ugcaacgaau gccaaugcgu cccauccaaa      900

gucaccaaga aauaccacga agugcuacaa cuaagaccaa aaaccggcgu ccgcggacuc      960

cacaaaucuc ucaccgacgu agcccuagaa caccacgaag aaugcgacug cgucugccgc     1020

ggcuccaccg gcggcuaa                                                   1038


<210>  1071
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  1071
augcaccgcc ucauauuugu cuacacacug auaugcgcca acuucuguuc augccgcgac       60

accuccgcca ccccccaauc ugccuccaua aaagcccuca gaaacgccaa ccuacgacgc      120

gacgaccucu accgacgcga cgaaacaaua caagucaaag gcaacggcua cguacaaucc      180

ccacgcuucc ccaacuccua cccccgcaac cuccuccuca ccuggcggcu acacucccaa      240

gaaaacaccc gcauacagcu uguauucgac aaccaauucg gccuagaaga agccgagaac      300

gacaucugcc gauacgacuu cgucgaaguc gaagacauca gcgaaaccuc caccaucauc      360

agaggaagau ggugcggcca caaagaaguc cccccucgaa ucaaaucccg cacaaaccag      420

auaaaaauaa cauucaaauc cgacgacuac uucgucgcca aacccggcuu caaaaucuac      480

uacucccucc ucgaagauuu ccaacccgcc gccgccuccg aaacaaacug ggaauccguc      540

accuccucca uauccggugu cucauacaac uccccaagcg ucacagaccc aacccucauu      600

gcagacgcac uagacaaaaa aaucgccgaa uucgacaccg ucgaggaccu ccuaaaauac      660

uucaaccccg aauccuggca agaagaccuc gaaaacaugu accucgacac accccgcuac      720

agaggccgcu ccuaccacga ccgcaaaucc aaggucgacc ucgaccgccu caacgacgac      780

gccaaacgcu acagcugcac accccgcaau uacaguguca acaucagaga ggaacuaaaa      840

cuagccaacg uagucuucuu cccacgcugc cuacuaguac agcgaugcgg cggcaacugc      900

ggcugcggca ccgugaacug gcgguccugc accuguaacu ccggcaaaac aguaaaaaaa      960

uaucacgaag uccuacaguu ugaacccgga cacaucaaac gccguggccg cgccaaaacu     1020

auggcccucg uugacaucca acucgaccac cacgaacgcu gcgacugcau augcucuucc     1080

cgcccacccc gauaa                                                      1095


<210>  1072
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  1072
auggucaccc auucaaaauu ccccgccgcc ggcauguccc gcccccucga caccucccuc       60

cgccucaaaa cauucuccuc caaauccgaa uaccaacucg ucgucaacgc cguccgcaaa      120

cuccaagaau ccggcuucua cuggucugcc gucaccggag gcgaagccaa ccuccuacua      180

ucagccgaac cagcuggcac cuuccuaauc cgugacuccu ccgaccaacg ccacuucuuc      240

acccucucag ucaaaaccca auccggcacc aaaaaccucc gcauccaaug cgaaggcgga      300

uccuucuccc uacaauccga cccccgcuca acucaaccag ucccccgauu cgacugcguc      360

cucaaacucg uccaccacua caugccccca cccggagccc ccuccuuccc cuccccaccc      420

accgaacccu ccuccgaagu ccccgaacaa cccuccgccc aaccccuccc cggaucacca      480

ccccgccgcg ccuacuacau cuacuccggc ggcgagaaaa ucccccuagu ccucucccgc      540

ccacucucau ccaauguugc cacccuacaa caccucugcc guaaaaccgu aaacggacac      600

cuagacuccu acgaaaaagu uacccaacua cccggcccca uccgcgaauu ucucgaccaa      660

uacgaugcac cccucuaa                                                    678


<210>  1073
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  1073
augguccccu ccgccggcca acuagcccuc uucgcccuag gcaucguccu cgcagccugu       60

caagcacucg aaaacuccac cuccccccuc ucagccgacc cacccguagc cgcagccgua      120

gucucccacu ucaacgacug ccccgacucc cacacccaau ucugcuucca cggaaccugc      180

cgauuccucg uccaagaaga caaacccgcc ugcguaugcc acuccggcua cgucggcgcc      240

cgcugcgaac acgccgaccu ccuagccgua guagccgccu cacaaaaaaa acaagccaua      300

accgcacucg uagucgucuc caucgucgcc cucgccgucc uuauaauaac cugcguccuc      360

auccacugcu gccaaguacg caaacacugc gaauggugcc gcgcccucau cugcagacac      420

gaaaaacccu ccgcacuacu caaaggccgc accgccugcu gccauuccga aaccguagua      480

uaa                                                                    483


<210>  1074
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  1074
augccaccau ccggccuacg ucuccucccu cuccuccugc cacuccucug gcuauuaguc       60

cuaacaccag gccgcccagc cgccggccuc ucaaccugca aaacuaucga cauggaacuu      120

gucaaacgca aacgaauaga agccauccgc ggccaaaucc uauccaaacu ccgccucgcc      180

uccccacccu cacaaggcga aguaccaccc ggaccccuac ccgaagccgu ccuugcacuc      240

uauaacucca cccgcgaccg aguugcugga gaaucagccg aacccgaacc agagccagaa      300

gccgacuacu acgccaaaga agucacccgc guacucaugg ucgaaacaca caacgagaua      360

uacgauaaau ucaagcaauc cacccacucc auauacaugu ucuucaacac cucagaacua      420

cgagaagccg uccccgaacc cguccuacua ucacgagccg aacuucgucu ccuccgacuc      480

aaacucaagg ucgaacaaca cgucgaacuc uaccaaaaau auucaaacaa cucauggcgc      540

uaccuaucaa accgccuacu agcaccauca gacucacccg aauggcuauc auucgacguc      600

accggagucg uccgccaaug gcuaucacga ggaggcgaaa ucgaaggcuu cagacucuca      660

gcccacugcu ccugcgacuc ccgagacaac acccuccaag ucgacaucaa cggcuucacc      720

accggccgac gcggagaccu cgccacaaua cacggaauga accgacccuu ccuacuccuc      780

auggcaacac cacucgaacg cgcccaacac cuccaaucuu cccgccaccg ccgagcccug      840

gacaccaacu acugcuucuc cuccacugag aaaaauugcu gcgugagaca acucuacauc      900

gacuuccgca aagaccucgg cuggaaaugg auccacgaac caaaaggcua ccacgcaaac      960

uucugccucg gccccugccc auacauaugg ucccuagaca cccaauacuc caaaguucua     1020

gcccuauaca accaacacaa ccccggcgcc uccgcggcuc ccugcugcgu uccccaagcc     1080

cucgaacccc ucccaauagu cuacuacguc ggccgcaaac caaaagucga acaacucucc     1140

aacaugaucg uccgauccug caaaugcucc uaa                                  1173


<210>  1075
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  1075
augcacuacu gcguacucuc agccuuccuc auccuccacc ucgucaccgu cgcacuauca       60

cuaucuaccu gcagcacacu cgauauggac caauucaugc gcaaacgcau agaagcuauc      120

cguggccaaa uccuauccaa acucaagcuc accagcccac ccgaagacua uccugaaccc      180

gaagaagucc cacccgaagu aaucuccauc uacaacucca cacgcgaccu ccuacaagaa      240

aaagccuccc gacgcgcagc cgccugcgaa cgagagcgcu ccgacgaaga auacuacgcc      300

aaagaaguau acaagauaga caugccaccc uucuucccuu ccgaaaacgc cauaccccca      360

accuucuacc gcccauacuu ccgcaucguc cgcuucgacg ucucugcuau ggagaaaaau      420

gcauccaacc ucgucaaagc cgaguuccgc guauuccgcc uacaaaaccc caaagcgcgc      480

gucccugaac aacgcaucga acucuaccag auccucaaau ccaaagaucu uaccucgccc      540

acacaacgcu acaucgacuc caaagucgua aagacccgcg ccgaaggaga auggcucucc      600

uucgacguaa ccgacgccgu ccacgaaugg cuacaccaca aagaccgcaa ccucggcuuc      660

aaaaucuccc uacacugccc cugcugcacc uucguccccu ccaacaauua caucaucccc      720

aauaaauccg aagaacucga agccagauuc gccggcaucg acggcaccuc aaccuacaca      780

uccggcgacc agaaaaccau caaaucaacc cgcaagaaaa acuccggcaa aaccccacau      840

cuccuccuca ugcuucuccc uucauaccgu cucgaaucuc aacaaaccaa ccgacgcaag      900

aaacgcgccc ucgacgccgc cuacuguuuc cgcaacgucc aagacaacug cugccuacga      960

ccccucuaca uagacuucaa acgcgaccuc ggcuggaaau ggauccacga acccaaaggc     1020

uacaacgcua acuucugcgc gggcgccugc cccuaccuau gguccuccga cacccaacac     1080

ucacgcgucc ucucccucua caacaccauc aauccugaag ccuccgccuc acccugcugc     1140

gucucccaag accucgaacc acucaccaua cuauacuaca ucggcaaaac gccuaaaaua     1200

gaacaacuau cuaacaugau cgucaaaucc uguaaaugca gcuaa                     1245


<210>  1076
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  1076
augaaaaugc accuccaacg cgcccuaguc guacucgcac uacucaacuu ugccaccgua       60

ucacuuucac ucuccacaug caccacacuc gacuuuggcc acaucaaaaa gaaacgaguc      120

gaagcuauac gaggccaaau ccuaucaaaa cuacgccuca cauccccacc cgaacccaca      180

guaaugaccc acguccccua ccaaguacuc gcccuauaca acuccacccg cgaacuccua      240

gaagaaaugc acggagaaag agaagaagga ugcacccagg aaaacaccga aucagaauac      300

uacgccaaag aaauacacaa auucgacaug auccaaggcc ucgccgaaca caacgaauua      360

gccgucugcc ccaaagguau cacuagcaaa guauuccgau ucaacguuuc cucggucgag      420

aaaaaccgca ccaaccuauu ccgagccgag uuccgugucc uccgcguccc caacccaagc      480

ucaaaacgca acgaacaacg caucgaacuu uuccaaauac uaagacccga cgaacacauc      540

gccaaacaac gcuacauagg cggcaaaaac cucccaaccc gcggcaccgc agaauggcuc      600

ucuuucgacg ucaccgacac cguacgugaa uggcuacuca gacgcgaauc caaccuaggu      660

cuagaaaucu caauacacug ccccugccac accuuccaac caaacggaga cauccucgaa      720

aacauccacg aagucaugga aaucaaauuc aaaggagucg acaaugaaga cgaccacgga      780

cgaggcgacc ucggacgacu caaaaagcaa aaagaccacc acaaccccca ccucauccua      840

augaugaucc caccccaccg ccucgacaac cccggacaag gcggccaacg caagaaacgc      900

gcccucgaca ccaacuacug cuuccgcaac cuagaagaaa acugcugcgu acgcccccuc      960

uacaucgacu uccgacaaga ccuaggcugg aaaugggucc acgaacccaa aggauacuac     1020

gcaaauuucu gcagcggacc augcccauac cuacgguccg ccgacacaac ccacuccaca     1080

guccuaggac uuuauaacac ccuaaaccca gaagccuccg ccucccccug cugugucccc     1140

caagaccuug aaccucucac cauccuuuac uacgucggca gaacccccaa agucgaacaa     1200

cuauccaaca uggucgucaa auccugcaaa ugcuccuaa                            1239


<210>  1077
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  1077
auggcacccg uugcagucug ggcagcccuu gccgucggcc ucgaacucug ggccgcugcc       60

cacgcccucc ccgcccaagu ugccuucacu ccuuacgccc cagaaccagg cuccacaugc      120

cgacuccgag aauacuauga ccaaacagcc caaaugugcu gcuccaagug cucccccggc      180

caacacgcca aagucuucug uaccaaaacc ucugacaccg ucugcgacuc cugcgaagac      240

uccacuuaca cccaacuaug gaacugggua cccgaaugcc ucuccugcgg cuccagaugc      300

ucauccgacc aagucgaaac ccaagcaugc acacgcgaac aaaaccgaau cugcacaugc      360

aggcccggau gguacugcgc acucuccaaa caagaaggcu gccgccucug cgcaccccuc      420

cgaaaaugcc gaccaggcuu cggcgucgcc cgcccaggaa cagaaaccuc cgacguaguc      480

ugcaaacccu gcgccccugg cacuuucucc aacacaacca gcucaaccga cauaugccgc      540

ccacaccaaa ucugcaacgu cguugcaaua cccggcaacg cauccaugga cgccgucugc      600

accuccacau cgcccacccg auccauggca cccggcgccg uccaccuccc ccaaccuguc      660

ucaacccgau cacaacacac acaacccacc cccgaacccu caaccgcccc auccaccuca      720

uuccuucuac ccaugggccc cuccccaccc gccgaaggcu ccaccggaga cuucgcccuc      780

ccagucggcc uaaucgucgg cgucaccgcc cuaggccugc ucaucaucgg agucgucaac      840

ugcguaauca ugacccaagu caaaaagaag ccccuauguc uccaaagaga agcaaaagua      900

ccucaccucc ccgccgacaa agcccgcggc acacaaggcc ccgaacaaca acaccuccua      960

aucaccgccc caucauccuc cucaucaagc cucgaaucau cagcaucagc ucucgaccgc     1020

cgcgccccaa ccagaaacca accccaggcc ccaggcguag aagccuccgg agccggagaa     1080

gcccgagccu caacaggcuc cuccgacagc ucucccggcg gccacggcac acaaguaaac     1140

guaaccugca ucgucaaugu augcucguca uccgaccauu ccucccaaug cucaagccaa     1200

gccucaucaa ccaugggcga caccgacuca agcccaucug aaucccccaa agacgaacaa     1260

guacccuuca guaaagaaga augugccuuc cgaucccaau uagaaacccc cgaaacacuc     1320

cuaggaucca ccgaagaaaa acccuuaccc cucggugucc cagacgccgg caugaaaccc     1380

uccuaa                                                                1386


<210>  1078
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  1078
augccgguca ugcgcuuguu cccgugcuuu cuacagcucu uggcagggcu cgcacuccca       60

gccgugcccc cgcaacagug ggcguuaucg gccgggaacg ggagcucgga aguggaagug      120

guaccguucc aggaagugug ggggcgcucg uacugucgcg cgcuagagcg ccuggucgau      180

gucgugagug aguacccgag cgaggucgag cacauguucu cgcccucaug cgugagcuug      240

cucaggugca cgggcuguug cggggacgag aaccugcacu gugucccggu cgagaccgcg      300

aacgugacca ugcaauugcu caagaucagg agcggggaca ggcccucgua cguggaauug      360

accuucagcc agcacguacg cugugaaugu cgcccacuca gggaaaagau gaagccagaa      420

cgcaggcgac cgaaagggcg cgggaaaagg cgcagagaaa agcaaaggcc cacagacugu      480

cacuuaugcg gggacgcggu cccgaggcgc uga                                   513


<210>  1079
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  1079
augacagacc gccagacaga caccgcgcca ucgcccucgu accaccuccu gcccgggaga       60

aggcgcacgg ucgacgccgc agccucgcga ggacaagggc ccgagccagc gccaggaggc      120

gggguagagg gcgugggagc gcgagggguc gcgcucaaac ucuucgucca gcuucugggc      180

ugcagcaggu ucgggggcgc aguagugcgc gcaggcgaag ccgagcccuc aggcgcggcc      240

aggagcgcaa gcucaggcag agaggaaccc cagcccgagg agggggaaga agaagaggaa      300

aaagaagaag aaaggggucc acaauggcgc cugggcgcgc gcaagccagg aaguuggacc      360

ggagaagcag cagugugcgc ggacucugca ccagccgcgc gagcgcccca ggcauuggcc      420

agagcaucag gcagaggagg acgaguggca agaagaggag ccgaggaauc aggaccgccc      480

cauagcccaa gcaggcgagg gagugcgagc agagccggac cagggcgcgc aagcgagaca      540

augaacuucc uccugagcug gguacacugg ucgcuagcac uguugcucua ccuccaucac      600

gcaaaaugga gccaggccgc gccaauggcc gagggaggag gacaaaacca ccacgaggua      660

gugaaauuca uggacgucua ccaaaggagc uauugccacc ccauagaaac gcuaguggac      720

auauuccagg aauauccaga cgaaauagag uacauauuca aaccaagcug cgugccgcuc      780

augaggugcg gcggaugcug uaacgaugaa gggcuagagu gcguacccac ggaagagagc      840

aacaucacca ugcagaucau gaggauaaaa ccgcaccagg gccagcacau aggagagaug      900

ucauuccugc aacacaacaa gugcgagugc cggcccaaga aagaccgagc aagacaggaa      960

aagaaaucag uaaggggaaa gggcaaggga cagaaaagaa aaagaaagaa gaguagguac     1020

aagagcugga guguauacgu aggggcgaga ugcugccuga ugccauggag ccuaccggga     1080

ccgcacccau gcggacccug cagcgaacgc aggaaacacc uguucgucca ggacccacaa     1140

acaugcaagu guucaugcaa gaacacagac ucgcgcugua aagcacgcca acucgagcuu     1200

aacgaaagga caugccgcug cgacaaaccc aggagauaa                            1239


<210>  1080
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  1080
augaacuucc uacucagcug gguccacugg ucacucgccc uccuccucua ccuccaccac       60

gccaaauggu cccaagccgc ccccauggcc gaaggcggcg gccaaaacca ccacgaagua      120

guaaaauuca uggacguaua ccaacgcagc uacugccacc ccaucgaaac ccuaguagac      180

aucuuccaag aauaccccga cgaaaucgaa uacauauuca aacccuccug cgucccacuc      240

augcgcugcg gcggcugcug caacgacgaa ggccucgaau gcguccccac agaagaaagc      300

aacaucacaa ugcagauaau gcgaaucaaa ccccaccaag gccagcacau cggcgaaaug      360

ucauuccucc aacacaacaa augcgaaugc cgaccaaaaa aagaccgcgc aagacaagaa      420

aaaaaauccg ucagaggcaa aggcaaaggc caaaaacgaa aacgcaaaaa aucccgcuac      480

aaaagcuggu cagucuacgu aggcgcccgc ugcugccuca ugccaugguc ccuccccggc      540

ccccaccccu gcgggcccug cagcgaacgc cgcaaacacc ucuucgucca agacccacaa      600

accugcaaau gcuccugcaa aaacaccgac ucccgcugca aagcccgcca acucgaacua      660

aacgaacgca ccugccgcug cgacaaaccc cgaagauaa                             699


<210>  1081
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  1081
augucccccc uccuccgccg acuccuacua gccgcccucc uacaacucgc ccccgcacaa       60

gcccccgucu cccaacccga cgcccccggc caccaacgca aagucguauc cuggauagac      120

guauacaccc gcgccaccug ccaaccacga gaagucguag ucccacucac agucgaacuc      180

augggcaccg ucgcaaaaca acucguacca ucaugcguaa ccguccaacg augcggcggc      240

ugcugccccg acgacggccu agaaugcguc cccaccggcc aacaccaagu cagaaugcaa      300

auccucauga uccgcuaccc cuccucccaa cucggcgaaa ugucacucga agaacacucc      360

caaugcgaau gccgccccaa aaaaaaagac ucagccguaa aacccgaccg cgccgccaca      420

ccacaccacc gaccccaacc ccgcucaguc ccaggcuggg acuccgcccc cggcgcaccc      480

ucccccgccg acaucaccca ccccaccccc gcacccggcc ccuccgcaca cgccgcccca      540

uccaccaccu ccgcccucac ccccggcccc gccgccgccg ccgccgacgc cgccgccagc      600

uccgucgcaa aaggcggcgc cuaa                                             624


<210>  1082
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  1082
augcaccucc ucggauucuu cuccgucgcc ugcucccuac ucgccgccgc acuccucccc       60

ggcccacgcg aagcaccagc agccgccgcc gcauucgaau caggccucga ccuauccgac      120

gccgaaccag acgccggcga agccaccgcc uaugcaagca aagaccucga agaacaacua      180

cgauccguau cauccgugga cgaacuaaug accguccucu acccagaaua cuggaaaaug      240

uacaaaugcc aacuccgaaa aggcggaugg caacauaacc gcgaacaagc caaccucaac      300

agccgaaccg aagaaacaau caaauucgcc gccgcccacu acaacacgga aauacuaaaa      360

uccaucgaca acgaauggag aaaaacacaa ugcaugcccc gugaagucug caucgacguc      420

ggcaaagaau uuggcgucgc caccaacaca uucuucaaac cacccugcgu cucaguauac      480

cgaugcggcg ggugcugcaa cuccgaaggc cuacaaugca ugaacaccuc caccucauac      540

cucucaaaaa cccucuucga aauaacaguu ccacucagcc aaggccccaa acccgucacg      600

auauccuucg caaaccauac uucaugccgc ugcaugucaa aacuugacgu auaccgccaa      660

guccacucca ucauccgaag aucacuaccc gccacccuac cccaauguca agccgccaac      720

aaaaccugcc ccaccaacua cauguggaac aaccacauuu gccgcugccu agcccaagaa      780

gacuucaugu ucucaucgga cgccggcgac gacucaaccg acggcuucca cgacauaugc      840

ggccccaaca aagaacuaga cgaagaaaca ugccaaugcg ucugccgcgc cggccuccga      900

cccgcauccu gcggacccca caaagaacug gaccgcaacu caugccaaug cgucugcaaa      960

aacaaacucu uccccuccca augcggcgca aaccgcgagu ucgacgaaaa uaccugccaa     1020

ugcgucugca agcgaaccug cccacgcaac caaccccuca accccggaaa gugcgccugc     1080

gaaugcaccg aaagcccaca aaaaugccuu cucaaaggaa agaaauucca ccaccaaacc     1140

ugcucaugcu accgccgccc cugcaccaac cgccaaaaag ccugcgaacc cggcuucuca     1200

uacuccgaag aaguaugccg cugcguucca agcuacugga aacgccccca aauguccuaa     1260


<210>  1083
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  1083
auguaccgag aauggguagu cgucaacguc uucaugaugc ucuacgucca acugguccaa       60

gguucaucca acgaacaugg ccccgucaaa cgcuccuccc agagcacccu cgagcgcucc      120

gaacaacaaa uccgcgcugc cuccucucua gaagaacuuc uccgaaucac ccacucugaa      180

gacuggaaau uauggcgaug ccgccuacgu cucaagagcu ucaccucaau ggacucccga      240

uccgcauccc accgcucuac acgauucgcc gccaccuucu acgacaucga aacccucaaa      300

gucauagacg aagaauggca acgcacccaa ugcuccccaa gggaaaccug cgucgaagua      360

gccuccgaac ucggcaaauc caccaacaca uucuucaaac cucccugcgu caacgucuuc      420

cgcugcggcg gcugcugcaa cgaagaaucc cucaucugca ugaacacauc caccuccuac      480

auauccaaac aacuauucga aauuucuguc ccccucaccu cgguccccga acucgucccc      540

gucaaaguag ccaaccacac cggcugcaaa ugccugccca ccgccccacg acaccccuau      600

uccaucaucc gacgcuccau acagauuccc gaagaagacc gaugcuccca cucaaagaaa      660

cucugcccca uagacaugcu augggacuca aacaaaugca aaugcguccu ccaagaagaa      720

aacccacucg ccggcacuga agaccacucg caccuccaag aacccgcccu cugcggaccc      780

cacaugaugu ucgacgaaga ccgcugcgaa ugcgucugca aaaccccaug ccccaaagac      840

cucauccaac accccaaaaa cugcucaugc uucgaaugca aagaaucccu cgagaccugc      900

ugccaaaaac acaaacucuu ccaccccgau accugcuccu gcgaagaccg cugccccuuc      960

cacacacgcc caugcgccuc cggcaaaacc gcaugcgcaa aacacugccg uuucccaaaa     1020

gaaaaacgcg ccgcccaagg cccccacucc cgcaaaaacc ccuaa                     1065


<210>  1084
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  1084
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

caaaccuggg cc                                                           72


<210>  1085
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  1085
auggacgcca ugaaacgcgg ccucugcugc guccuccucc ucugcggcgc cgucuucguc       60

ucccccucc                                                               69


<210>  1086
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  1086
augggcgugc acgagugccc ggccuggcuc uggcucuugc ucucgcucuu gagcuugccc       60

uugggcuugc ccgugcucgg g                                                 81


<210>  1087
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  1087
augaaauggg ucaccuucau cucccuccuc uuccucuucu ccuccgccua cucc             54


<210>  1088
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from 
       Artificial____cleavage site-Furin

<400>  1088
aggaggagga ggaagagg                                                     18


<210>  1089
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  1089
auggacuccg acgaaaccgg cuucgaacac ucaggccucu gggucuccgu acuagccggc       60

cuccuccucg gcgccugcca agcccacccc auccccgacu ccucaccccu ccuacaauuc      120

ggcggccaag uccgccaacg cuaccuauac accgacgacg cccaacaaac cgaagcccac      180

cucgaaaucc gcgaagacgg caccgucggc ggcgccgccg accaaucccc cgaaucccua      240

cuacaacuca aagcccucaa accuggaguc auccaaauac ucggcgucaa aaccucccgc      300

uuccucugcc aacgccccga cggagcccuc uacggcuccc uccacuucga cccagaagcc      360

ugcucuuucc gagaacuccu cuuagaagac ggcuacaacg ucuaccaauc ugaagcccac      420

ggccuccccc uucaccuccc cggaaacaaa ucaccccacc gcgaccccgc accccgcggc      480

ccagccagau uccucccccu ccccggccuc ccaccagccc uccccgaacc acccggcauc      540

cucgcacccc aaccacccga cgucggcucc uccgaccccc ucucaauggu cggccccucc      600

caaggccgcu cccccucaua cgccucauaa                                       630


<210>  1090
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  1090
augcacagcu ucccaccccu ccuccuccuc cuguucuggg gcgucgucuc acacuccuuu       60

cccgcuaccc ucgaaaccca agaacaagac gucgaccucg uacaaaagua ccucgaaaaa      120

uacuacaacc uuaaaaacga cggccgucaa gucgaaaagc gccgcaacuc aggccccguc      180

guugaaaaac ucaaacaaau gcaagaauuu uucggccuga aagucacagg aaaacccgac      240

gccgaaaccc ucaaagucau gaaacaaccc cgcugcggag uccccgacgu agcccaauuc      300

guccuaaccg aaggcaaccc ccgcugggaa caaacccacc ucacauaccg caucgaaaac      360

uacacccccg accuuccccg cgccgacguc gaccacgcca uagaaaaagc auuccaauua      420

ugguccaacg ucaccccacu caccuucacu aaggucuccg aaggccaagc agacauaaug      480

aucucuuucg uccgcggcga ccaccgagac aacucccccu ucgacggccc cggaggcaac      540

cuggcccacg cauuccaacc aggccccggc aucggaggag acgcccacuu cgacgaagac      600

gaacgcugga caaacaauuu cagagaauac aacuuacauc gcgucgccgc ccacgaacuc      660

ggccacagcc ucggccucuc acacuccaca gauaucggcg cccuaaugua ccccuccuac      720

accuucuccg gcgacgucca acuagcccaa gacgacauag acggcaucca agccauauac      780

ggccgauccc aaaaccccgu acagcccauc ggaccacaaa cucccaaagc cugcgacucc      840

aaacucaccu ucgacgccau caccacaaua cgaggcgaag ugauguucuu caaagacaga      900

uucuauauga gaaccaaccc guucuacccc gaagucgaac uuaacuucau cucagucuuc      960

uggccacaac uaccaaacgg ccucgaagca gccuacgaau uugccgaccg cgacgaaguc     1020

cgauucuuca agggcaacaa auacugggcc guccaaggcc aaaacguccu gcacggcuac     1080

ccaaaagaca ucuauuccag cuucggcuuc ccacgcacug ucaaacauau cgaugccgcc     1140

cucagcgaag aaaacacagg caaaacauac uucuucgucg cuaacaaaua cuggcgcuac     1200

gaugaauaca aacgcuccau ggacccaggc uauccuaaaa ugaucgccca cgacuucccc     1260

ggcaucggcc acaaggucga ugccgucuuc augaaggacg gauucuucua cuucuuccac     1320

ggaacccgcc aauacaaguu cgaccccaaa acuaagcgaa uccucacccu ccaaaaagcc     1380

aacuccuggu ucaacugccg caaaaacuaa                                      1410


<210>  1091
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  1091
augcauucau ucccaccacu acuacuccuc cuauucuggg gagucgucuc ccauuccuuc       60

guccucacag aaggcaaccc ccgcugggaa caaacccacc ucaccuaccg cauagaaaac      120

uacaccccag accucccccg cgccgacguc gaccacgcca ucgaaaaagc guuccaacua      180

uggucuaacg uaacaccccu caccuucacc aaagucuccg aaggccaagc cgacauaaug      240

aucucauucg ucagaggcga ccaccgcgac aacucucccu ucgacggccc cggaggcaac      300

cucgcacacg ccuuccaacc cggccccgga aucggcggcg acgcccacuu cgacgaagac      360

gaacgcugga ccaacaacuu ccgagaauac aaccuccacc gcgucgccgc acacgaacuc      420

ggccacagcc ucgggcucuc acacuccacc gacaucggug cccucaugua ccccucauac      480

acauucucug gcgacgucca acucgcacaa gacgacaucg acggcaucca agccaucuac      540

ggccgauccc aaaacccagu ccaacccaua ggcccacaga cacccaaagc augcgacucc      600

aaacucaccu ucgacgccau aaccaccauc cgcggcgaag uaauguucuu caaagacaga      660

uucuacaugc gcaccaaccc cuucuaccca gaaguugaau uaaacuucau cuccgucuuc      720

uggccacagc ucccaaacgg ucucgaagcc gcauacgaau uugcagaccg agacgaagua      780

cgauucuuca aaggcaacaa auauugggcc guacaggggc aaaauguccu ccacggcuac      840

ccuaaagaca ucuacuccuc cuucggcuuc ccccgcacag ucaaacacau cgacgccgcc      900

cucuccgaag aaaacaccgg caaaaccuac uucuucgucg ccaacaaaua cuggcgauac      960

gacgaauaca aacgcuccau ggaccccgga uaccccaaaa ugaucgccca cgacuucccc     1020

ggcaucggcc acaaaguaga cgccguuuuc augaaagacg gauucuucua cuucuuccac     1080

ggaacaagac aguacaaauu cgacccaaag accaaacgga uccucacccu ccaaaaagca     1140

aacuccuggu ucaauugccg caaaaauuaa                                      1170


<210>  1092
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  1092
augaagaaga acauccugaa gauccucaug gacagcuacu ccaaggagag caagauccag       60

accgugcgcc gggucaccuc cgugagccug cuggccgugu accucacgau gaacaccucc      120

agccuggucc uggccaagcc caucgagaac accaacgaca ccuccaucaa gaacguggag      180

aagcuccgca acgcgccgaa cgaggagaac agcaagaagg uggaggacuc caagaacgac      240

aaggucgagc acgugaagaa caucgaggag gccaaggugg agcaggucgc ccccgagguc      300

aagagcaagu ccacgcugcg gagcgccucc aucgccaaca ccaacagcga gaaguacgac      360

uucgaguacc ugaacggccu cuccuacacc gagcugacca accugaucaa gaacaucaag      420

uggaaccaga ucaacggccu cuucaacuac agcacggggu cccagaaguu cuucggggac      480

aagaaccgcg ugcaggcgau caucaacgcc cugcaggaga gcggccggac cuacaccgcc      540

aacgacauga aggggaucga gaccuucacg gaggugcugc gcgccggcuu cuaccucggc      600

uacuacaacg acgggcuguc cuaccugaac gaccggaacu uccaggacaa gugcaucccc      660

gcgaugaucg ccauccagaa gaaccccaac uucaagcucg gcaccgccgu gcaggacgag      720

gugaucacca gccuggggaa gcugaucggc aacgccagcg ccaacgcgga ggucgugaac      780

aacugcgugc cgguccucaa gcaguuccgc gagaaccuga accaguacgc ccccgacuac      840

gugaagggga ccgccgugaa cgagcugauc aagggcaucg aguucgacuu cuccggcgcc      900

gccuacgaga aggacgucaa gacgaugccc ugguacggga agaucgaccc cuucaucaac      960

gagcucaagg cgcugggccu guacgggaac aucaccagcg ccaccgagug ggccuccgac     1020

gugggcaucu acuaccucag caaguucggc cuguacucca ccaaccggaa cgacaucgug     1080

cagagccugg agaaggccgu cgacauguac aaguacggga agaucgccuu cguggcgaug     1140

gagcgcauca cgugggacua cgacggcauc ggguccaacg gcaagaaggu cgaccacgac     1200

aaguuccucg acgacgccga gaagcacuac cugccgaaga ccuacaccuu cgacaacggg     1260

accuucauca uccgggccgg cgacaaggug agcgaggaga agaucaagcg ccuguacugg     1320

gccucccggg aggucaagag ccaguuccac cgcguggugg gcaacgacaa ggcccucgag     1380

guggggaacg cggacgacgu ccugacgaug aagaucuuca acucccccga ggaguacaag     1440

uucaacacca acaucaacgg cgugagcacc gacaacgggg gccuguacau cgagccccgg     1500

gggaccuucu acacguacga gcgcacgccc cagcagucca ucuucagccu cgaggagcug     1560

uuccggcacg aguacaccca cuaccugcag gcccgcuacc ucguggacgg ccuguggggc     1620

caggggccgu ucuacgagaa gaaccggcug accugguucg acgagggcac cgccgaguuc     1680

uucgccgggu ccacccgcac cagcggcguc cucccccgga aguccauccu gggguaccug     1740

gcgaaggaca agguggacca ccgcuacagc cucaagaaga cccugaacuc cggcuacgac     1800

gacagcgacu ggauguucua caacuacggc uucgccgugg cccacuaccu guacgagaag     1860

gacaugccca cguucaucaa gaugaacaag gccauccuca acaccgacgu caagagcuac     1920

gacgagauca ucaagaagcu guccgacgac gccaacaaga acaccgagua ccagaaccac     1980

auccaggagc uggcggacaa guaccagggg gccggcaucc cccuggugag cgacgacuac     2040

cucaaggacc acggguacaa gaaggccucc gagguguaca gcgagaucuc caaggccgcc     2100

agccugacca acaccuccgu cacggcggag aagucccagu acuucaacac cuucacccug     2160

cgcggcaccu acacgggcga gaccagcaag ggggaguuca aggacuggga cgagaugagc     2220

aagaagcucg acggcacccu ggagucccug gccaagaaca gcugguccgg guacaagacc     2280

cucacggccu acuucaccaa cuaccgggug accagcgaca acaaggugca guacgacguc     2340

guguuccacg gcgugcugac cgacaacgcc gacaucucca acaacaaggc cccgaucgcg     2400

aaggucacgg ggcccagcac cggcgccgug ggccgcaaca ucgaguucuc cgggaaggac     2460

agcaaggacg aggacggcaa gaucgugagc uacgacuggg acuucgggga cggcgccacc     2520

ucccggggga agaacagcgu ccacgccuac aagaaggcgg gcaccuacaa cgugacgcug     2580

aaggugaccg acgacaaggg cgccaccgcc accgaguccu ucacgaucga gaucaagaac     2640

gaggacacca ccacccccau cacgaaggag auggagccca acgacgacau caaggaggcc     2700

aacgggccga ucgucgaggg cgugaccgug aagggggacc ucaacggcag cgacgacgcc     2760

gacaccuucu acuucgacgu caaggaggac ggggacguga ccaucgagcu gcccuacucc     2820

ggcagcucca acuucacgug gcugguguac aaggagggcg acgaccagaa ccacaucgcg     2880

agcgggaucg acaagaacaa cuccaagguc ggcaccuuca agagcaccaa ggggcgccac     2940

uacguguuca ucuacaagca cgacuccgcc agcaacaucu ccuacagccu caacaucaag     3000

ggccugggga acgagaagcu gaaggagaag gagaacaacg acuccagcga caaggccacc     3060

gugaucccca acuucaacac gaccaugcag ggcucccucc ugggcgacga cagccgggac     3120

uacuacuccu ucgaggucaa ggaggagggg gaggugaaca ucgagcugga caagaaggac     3180

gaguucggcg ugaccuggac ccuccacccc gagagcaaca ucaacgaccg caucacguac     3240

gggcaggucg acggcaacaa ggugagcaac aaggugaagc ugcggccggg caaguacuac     3300

cugcucgucu acaaguacuc cgggagcggc aacuacgagc ugcgcgugaa caaguga        3357


<210>  1093
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  1093
augaaguggg ugacauucau cagccuccuc uucuuauucu ccagcgccua cuccaucgcc       60

aacaccaaca gcgagaagua cgacuucgag uaccugaacg gccucucuua cacggagcug      120

accaaucuga ucaagaacau caaguggaac cagauuaacg gguuauucaa cuacagcacc      180

ggcucccaga aguucuucgg ggacaaaaac cgcguccagg cgauuaucaa cgcccugcag      240

gagagcgguc ggaccuacac cgcuaacgac augaagggga ucgagaccuu caccgagguu      300

cugcgcgccg gcuucuaccu cggcuacuac aacgacgggc uguccuaccu gaacgaccgg      360

aacuuccagg acaagugcau ccccgccaug aucgcgaucc agaagaaccc gaacuucaag      420

cucggcaccg ccgugcagga cgaggucauc acgagccugg ggaagcugau cggcaacgcc      480

uccgccaacg cggagguggu gaacaacugc guccccgugc ucaagcaauu ccgcgaaaac      540

cugaaccagu acgcccccga cuacguaaag gggaccgccg ucaacgagcu gaucaagggc      600

aucgaguucg acuuuagcgg cgccgccuac gagaaagacg ugaagaccau gcccugguac      660

gggaagaucg acccguucau caacgagcuc aaggcgcugg gccuguacgg gaacaucacc      720

uccgccacgg agugggccag cgacgugggc aucuacuacc ucuccaaguu cggccuguac      780

ucgaccaacc ggaaugacau cguacagucc cuggagaagg ccguggacau guacaaguac      840

gggaagaucg ccuucguggc gauggagcgc aucaccuggg acuacgacgg uaucgggagc      900

aacggcaaga aggucgacca cgacaaauuc cucgacgacg ccgagaagca cuaccugccc      960

aagaccuaca cguucgacaa cggcaccuuc aucauccggg ccggugacaa gguguccgag     1020

gagaagauca agcgccugua cugggccagc cgagagguca agagccaguu ccaccgcgug     1080

gugggcaacg acaaggcccu cgaggugggg aacgcggacg acguccugac caugaagauc     1140

uucaacuccc cugaggagua caaguucaac accaacauca acggcguguc cacggauaac     1200

gggggccugu acaucgagcc ccgggggacc uucuacaccu augagcgcac cccgcagcag     1260

uccaucuuca gccucgagga gcuguuucgg cacgaguaca cgcacuaccu gcaggcccgc     1320

uacuuagugg acggccugug gggccagggg cccuucuacg agaagaaccg gcugaccugg     1380

uucgacgagg gcaccgccga guucuucgcc gguuccaccc gcacgagcgg cguccucccc     1440

cgaaagucca uccuggggua ccuggccaag gacaaggugg accaccgcua cagccucaag     1500

aagacccuga acuccggcua cgacgacucg gacuggaugu ucuacaacua cggcuucgcg     1560

gucgcccacu accuguacga gaaggacaug cccaccuuca ucaagaugaa caaggccauc     1620

cucaacaccg acgugaaguc cuacgacgag aucaucaaga agcugagcga cgacgccaac     1680

aagaacacgg aguaccagaa ccacauccag gagcuggcgg acaaauacca gggugccggc     1740

aucccucucg uguccgacga cuaccugaag gaccacgggu acaagaaggc cagcgagguc     1800

uacuccgaga uuagcaaggc cgccucccug accaacacca gcgugaccgc ggagaagucc     1860

caguacuuca acacguucac ccuccggggc accuacaccg gcgaaaccag caagggggag     1920

uucaaggacu gggacgagau gagcaagaag cuggacggca cgcuggaauc ccuggccaag     1980

aacagcuggu ccggguacaa gacccucacc gccuauuuua ccaacuaccg cgugacgagc     2040

gacaacaagg uccaguacga cgugguguuc cacggcgucc ugaccgacaa cgccgacauc     2100

uccaacaaca aggcccccau cgcgaaggug accgggccca gcaccggcgc cgugggccgg     2160

aacaucgagu ucuccgggaa ggacucuaag gacgaggacg gcaagauagu cuccuacgac     2220

ugggacuucg gggacggcgc cacgucccgc gggaagaacu ccguccacgc cuacaagaag     2280

gccggcaccu acaacgugac ccugaagguc accgacgaca aaggcgcgac ggccaccgag     2340

agcuucacca ucgagaucaa gaacgaggac accacgaccc ccaucaccaa ggagauggag     2400

ccgaacgacg acaucaagga ggccaacggg cccaucgugg agggcgugac cgucaagggg     2460

gaccucaacg gcuccgacga cgcagacacg uucuacuucg augugaagga ggacggggac     2520

gugaccaucg agcugcccua cagcggcucc agcaacuuca ccuggcuggu cuacaaggag     2580

ggcgacgacc agaaccacau cgcguccggg aucgacaaga acaacagcaa ggugggcacc     2640

uucaagagca cgaaggggcg ccacuacgug uucaucuaca agcacgacuc cgccagcaac     2700

aucuccuaca gccucaacau caagggccug gggaacgaga agcugaagga gaaggagaac     2760

aacgacucca gcgacaaggc caccgucauc cccaacuuca acaccaccau gcagggcucc     2820

cuccugggcg acgacagccg ggacuacuac uccuucgagg ugaaggagga gggggaggug     2880

aacaucgagc uggacaagaa ggacgaguuc ggcgucacgu ggacccucca cccggaaucc     2940

aacauaaacg accgcaucac cuacggccag guggacggga acaagguguc caacaagguc     3000

aagcugcggc ccggcaagua cuaccugcuc guguacaagu acagcggguc cggaaacuac     3060

gagcugcgcg ugaacaagug a                                               3081


<210>  1094
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  1094
augaaguggg ugaccuucau cagccuccuc uuccuguucu ccagcgccua cuccaugaag       60

aagaacaucc ugaagauccu cauggacagc uacuccaagg agagcaagau ccagaccguc      120

cgccggguga cguccgugag ccugcuggcc gucuaccuca ccaugaacac cuccagccug      180

gugcuggcga agcccaucga gaacaccaac gacacgucca ucaagaacgu ggagaagcuc      240

cgcaacgccc cgaacgagga gaacagcaag aaggucgagg acuccaagaa cgacaaggug      300

gagcacguga agaacaucga ggaggccaag gucgagcagg ucgcccccga ggucaagagc      360

aaguccaccc ugcggagcgc cucccgccgg cgccggaagc gcaucgcgaa caccaacagc      420

gagaaguacg acuucgagua ccugaacggc cucuccuaca ccgagcugac gaaccugauc      480

aagaacauca aguggaacca gaucaacggg cuguucaacu acagcaccgg cagccagaag      540

uucuucgggg acaagaaccg ggugcaggcc aucaucaacg cccugcagga guccggccgc      600

accuacaccg ccaacgacau gaaggggauc gagacguuca ccgaggugcu gcgggcgggc      660

uucuaccucg gcuacuacaa cgacgggcug agcuaccuga acgaccgcaa cuuccaggac      720

aagugcaucc ccgccaugau cgccauccag aagaacccca acuucaagcu cggcaccgcc      780

gugcaggacg aggugaucac cucccugggg aagcugaucg gcaacgccag cgcgaacgcc      840

gaggugguga acaacugcgu cccggugcuc aagcaguucc gggagaaccu gaaccaguac      900

gcccccgacu acgugaaggg gacggccguc aacgagcuga ucaagggcau cgaguucgac      960

uucuccggcg ccgcguacga gaaggacgug aagaccaugc ccugguacgg gaagaucgac     1020

cccuucauca acgagcucaa ggcccugggc cuguacggga acaucaccag cgccaccgag     1080

ugggccuccg acgugggcau cuacuaccuc agcaaguucg gccuguacuc cacgaaccgc     1140

aacgacaucg uccagagccu ggagaaggcc guggacaugu acaaguacgg gaagaucgcg     1200

uucgucgcca uggagcggau caccugggac uacgacggca ucggguccaa cggcaagaag     1260

guggaccacg acaaguuccu cgacgacgcc gagaagcacu accugccgaa gaccuacacc     1320

uucgacaacg ggacguucau cauccgcgcc ggcgacaagg ugagcgagga gaagaucaag     1380

cggcuguacu gggccucccg cgaggucaag agccaguucc accggguggu gggcaacgac     1440

aaggcgcucg aggucgggaa cgccgacgac gugcugacca ugaagaucuu caacuccccc     1500

gaggaguaca aguucaacac caacaucaac ggcgugagca ccgacaacgg gggccuguac     1560

aucgagcccc gcgggacguu cuacaccuac gagcggacgc cccagcaguc caucuucagc     1620

cucgaggagc uguuccgcca cgaguacacc cacuaccugc aggcccgcua ccucgucgac     1680

ggccuguggg gccaggggcc guucuacgag aagaaccggc ugaccugguu cgacgagggc     1740

accgccgagu ucuucgcggg guccacccgc accagcggcg ugcucccccg caagagcauc     1800

cugggguacc uggccaagga caagguggac caccgguacu cccucaagaa gacgcugaac     1860

agcggcuacg acgacuccga cuggauguuc uacaacuacg gcuucgccgu cgcccacuac     1920

cuguacgaga aggacaugcc caccuucauc aagaugaaca aggccauccu gaacaccgac     1980

gucaagagcu acgacgagau caucaagaag cucuccgacg acgcgaacaa gaacaccgag     2040

uaccagaacc acauccagga gcuggccgac aaguaccagg gggccggcau cccccuggug     2100

agcgacgacu accucaagga ccacggguac aagaaggccu ccgaggugua cagcgagauc     2160

uccaaggccg cgagccugac caacacgucc gugaccgccg agaaguccca guacuucaac     2220

accuucaccc ugcggggcac guacaccggc gagaccagca agggggaguu caaggacugg     2280

gacgagauga gcaagaagcu cgacggcacc cuggaguccc uggccaagaa cagcuggucc     2340

ggguacaaga cgcucaccgc cuacuucacc aacuaccgcg ugaccagcga caacaagguc     2400

caguacgacg ugguguucca cggcguccug acggacaacg ccgacaucag caacaacaag     2460

gcgccgaucg ccaaggugac cgggcccucc accggcgccg ugggccggaa caucgaguuc     2520

agcgggaagg acuccaagga cgaggacggc aagaucguca gcuacgacug ggacuucggg     2580

gacggcgcca ccucccgcgg gaagaacagc gugcacgcgu acaagaaggc cggcacguac     2640

aacgugaccc ugaaggucac cgacgacaag ggcgccaccg ccacggaguc cuucaccauc     2700

gagaucaaga acgaggacac caccacgccc aucaccaagg agauggagcc caacgacgac     2760

aucaaggagg ccaacgggcc gaucguggag ggcgugaccg ucaaggggga ccucaacggc     2820

agcgacgacg cggacaccuu cuacuucgac gugaaggagg acggggacgu gacgaucgag     2880

cugcccuacu ccggcagcuc caacuucacc uggcuggucu acaaggaggg cgacgaccag     2940

aaccacaucg ccagcgggau cgacaagaac aacuccaagg ugggcaccuu caagagcacc     3000

aaggggcggc acuacguguu caucuacaag cacgacuccg ccagcaacau cuccuacagc     3060

cucaacauca agggccuggg gaacgagaag cugaaggaga aggagaacaa cgacuccagc     3120

gacaaggcca cggucauccc caacuucaac accaccaugc agggcagccu ccugggcgac     3180

gacucccgcg acuacuacag cuucgaggug aaggaggagg gggaggugaa caucgagcug     3240

gacaagaagg acgaguucgg cgucaccugg acgcuccacc ccgaguccaa caucaacgac     3300

cggaucaccu acggccaggu ggacgggaac aaggugagca acaaggucaa gcugcgcccg     3360

ggcaaguacu accugcucgu guacaaguac uccgggagcg gcaacuacga gcugcgggug     3420

aacaaguga                                                             3429


<210>  1095
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  1095
augaacuucc ugaagaucau ccucaaccgc ggcaagacca ugaagcggaa gugccugagc       60

aagcgccuga ugcucgccau caccauggcc acgaucuuca ccgugaacuc cacccugccc      120

aucuacgcgg ccgucgacaa gaacaacgcc accgccgccg ugcagaacga gagcaagcgg      180

uacacggugu ccuaccugaa gacccucaac uacuacgacc uggucgaccu gcucgugaag      240

accgagaucg agaaccugcc ggaccuguuc caguacagcu ccgacgcgaa ggaguucuac      300

gggaacaaga cccgcaugag cuucaucaug gacgagaucg gccggcgcgc gccccaguac      360

acggagaucg accacaaggg gauccccacc cucguggagg ucgugcgggc cggcuucuac      420

cugggguucc acaacaagga gcugaacgag aucaacaagc gcuccuucaa ggagcgggug      480

auccccagca uccucgccau ccagaagaac ccgaacuuca agcugggcac cgagguccag      540

gacaagaucg uguccgccac cggccugcuc gccgggaacg agacggcccc gcccgaggug      600

gucaacaacu ucacccccau ccugcaggac ugcaucaaga acaucgaccg cuacgcccug      660

gacgaccuca agagcaaggc ccuguucaac gugcuggcgg ccccgaccua cgacaucacc      720

gaguaccucc gggccacgaa ggagaagccc gagaacaccc ccugguacgg caagaucgac      780

ggguucauca acgagcugaa gaagcuggcc cucuacggca agaucaacga caacaacucc      840

uggaucaucg acaacgggau cuaccacauc gcgccccugg gcaagcugca cagcaacaac      900

aagaucggca ucgagacccu caccgaggug augaaggucu acccguaccu guccaugcag      960

caccuccaga gcgccgacca gaucaagcgc cacuacgacu ccaaggacgc cgaggggaac     1020

aagauccccc uggacaaguu caagaaggag ggcaaggaga aguacugccc caagacguac     1080

accuucgacg acgggaaggu gaucaucaag gccggcgccc ggguggagga ggagaagguc     1140

aagcgccugu acugggccag caaggaggug aacucccagu ucuuccgggu guacggcauc     1200

gacaagcccc uggaggaggg gaacccggac gacauccuca ccauggucau cuacaacagc     1260

cccgaggagu acaagcugaa cuccgugcug uacggcuacg acaccaacaa cgggggcaug     1320

uacaucgagc ccgaggggac guucuucacc uacgagcgcg aggcgcagga gagcaccuac     1380

acccucgagg agcuguuccg gcacgaguac acgcacuacc ugcagggccg cuacgccgug     1440

cccggccagu gggggcggac caagcucuac gacaacgacc gccugaccug guacgaggag     1500

ggcggggccg agcuguucgc cggcagcacc cggacguccg ggauccuccc gcgcaagagc     1560

aucgucucca acauccacaa caccacccgc aacaaccggu acaagcugag cgacaccgug     1620

cacuccaagu acggcgccag cuucgaguuc uacaacuacg cgugcauguu cauggacuac     1680

auguacaaca aggacauggg cauccugaac aagcucaacg accuggccaa gaacaacgac     1740

gucgacgggu acgacaacua cauccgcgac cuguccagca acuacgcccu gaacgacaag     1800

uaccaggacc acaugcagga gcggaucgac aacuacgaga accucacggu gcccuucgug     1860

gccgacgacu accugguccg ccacgcguac aagaacccca acgagaucua cuccgagauc     1920

agcgaggugg ccaagcugaa ggacgccaag uccgagguga agaaguccca guacuucagc     1980

accuucaccc uccggggcag cuacaccggg ggcgccucca aggggaagcu ggaggaccag     2040

aaggccauga acaaguucau cgacgacagc cugaagaagc ucgacaccua cuccuggagc     2100

ggcuacaaga cgcugaccgc guacuucacc aacuacaagg ucgacuccag caaccgcgug     2160

accuacgacg uggucuucca cggcuaccug cccaacgagg gggacagcaa gaacucccuc     2220

ccguacggca agaucaacgg gacguacaag ggcaccgaga aggagaagau caaguucagc     2280

uccgagggca gcuucgaccc cgacgggaag aucguguccu acgaguggga cuucggcgac     2340

gggaacaaga gcaacgagga gaaccccgag cacuccuacg acaagguggg caccuacacc     2400

gucaagcuga aggugacgga cgacaagggg gagagcuccg ugagcaccac caccgccgag     2460

aucaaggacc uguccgagaa caagcucccc gucaucuaca ugcacgugcc caagagcggc     2520

gcccugaacc agaagguggu cuucuacggc aaggggacgu acgaccccga cggcuccauc     2580

gccggguacc agugggacuu cggcgacggg agcgacuucu ccagcgagca gaaccccucc     2640

cacguguaca ccaagaaggg cgaguacacc gugacccugc gggucaugga cagcagcggc     2700

cagauguccg agaagacgau gaagaucaag aucaccgacc cgguguaccc caucgggacc     2760

gagaaggagc ccaacaacag caaggagacc gccuccggcc ccaucgugcc ggggaucccc     2820

gucagcggca cgaucgagaa caccuccgac caggacuacu ucuacuucga cgugaucacc     2880

cccggggagg ugaagaucga caucaacaag cucggcuacg gcggggcgac cugggucgug     2940

uacgacgaga acaacaacgc cgugagcuac gccacggacg acggccagaa ccuguccggg     3000

aaguucaagg ccgacaagcc cggccgcuac uacauccacc uguacauguu caacgggagc     3060

uacaugccgu accggaucaa caucgagggc uccgucggcc gcuga                     3105


<210>  1096
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  1096
augaagcgca agugccugag caagcggcuc augcuggcca ucaccauggc caccaucuuc       60

acggugaacu ccacccugcc caucuacgcg gccgucgaca agaacaacgc caccgccgcc      120

gugcagaacg agagcaagcg cuacaccgug uccuaccuca agacgcugaa cuacuacgac      180

cuggucgacc uccuggugaa gaccgagauc gagaaccugc cggaccucuu ccaguacagc      240

uccgacgcga aggaguucua cggcaacaag acccggauga gcuucaucau ggacgagauc      300

gggcgccggg cgccccagua caccgagauc gaccacaagg gcauccccac gcugguggag      360

gucgugcgcg ccggguucua ccugggcuuc cacaacaagg agcucaacga gaucaacaag      420

cgguccuuca aggagcgcgu gauccccagc auccuggcca uccagaagaa cccgaacuuc      480

aagcugggga ccgaggucca ggacaagauc guguccgcca ccggccuccu ggccggcaac      540

gagaccgccc cgcccgaggu ggucaacaac uucacgccca uccugcagga cugcaucaag      600

aacaucgacc gguacgcccu cgacgaccuc aagagcaagg cccuguucaa cgugcucgcg      660

gccccgaccu acgacaucac cgaguaccug cgcgccacca aggagaagcc cgagaacacg      720

cccugguacg ggaagaucga cggcuucauc aacgagcuga agaagcucgc ccuguacggg      780

aagaucaacg acaacaacuc cuggaucauc gacaacggca ucuaccacau cgcgccccug      840

gggaagcucc acagcaacaa caagaucggc aucgagaccc ugaccgaggu gaugaagguc      900

uacccguacc uguccaugca gcaccuccag agcgccgacc agaucaagcg gcacuacgac      960

uccaaggacg ccgagggcaa caagaucccc cuggacaagu ucaagaagga ggggaaggag     1020

aaguacugcc ccaagaccua cacguucgac gacggcaagg ugaucaucaa ggccggggcc     1080

cgcguggagg aggagaaggu caagcggcug uacugggcca gcaaggaggu gaacucccag     1140

uucuuccgcg uguacggcau cgacaagccc cucgaggagg gcaacccgga cgacauccug     1200

accaugguca ucuacaacag ccccgaggag uacaagcuga acuccgugcu cuacggguac     1260

gacaccaaca acggcgggau guacaucgag cccgagggca ccuucuucac guacgagcgg     1320

gaggcgcagg agagcaccua cacccuggag gagcuguucc gccacgagua cacccacuac     1380

cuccaggggc gguacgccgu gcccggccag uggggccgca cgaagcugua cgacaacgac     1440

cggcugaccu gguacgagga gggcggggcc gagcuguucg ccgggagcac ccgcaccucc     1500

ggcauccugc cgcgcaagag caucgucucc aacauccaca acacgacccg gaacaaccgc     1560

uacaagcuga gcgacaccgu gcacuccaag uacggggcca gcuucgaguu cuacaacuac     1620

gcgugcaugu ucauggacua cauguacaac aaggacaugg gcauccucaa caagcugaac     1680

gaccuggcca agaacaacga cgucgacggc uacgacaacu acauccggga ccucuccagc     1740

aacuacgccc ugaacgacaa guaccaggac cacaugcagg agcgcaucga caacuacgag     1800

aaccugaccg ugcccuucgu ggccgacgac uaccuggucc ggcacgcgua caagaacccc     1860

aacgagaucu acuccgagau cagcgaggug gccaagcuca aggacgccaa guccgaggug     1920

aagaaguccc aguacuucag cacguucacc cugcgcggga gcuacaccgg cggggccucc     1980

aagggcaagc uggaggacca gaaggccaug aacaaguuca ucgacgacag ccucaagaag     2040

cuggacaccu acuccuggag cggguacaag acccugacgg cguacuucac caacuacaag     2100

gucgacucca gcaaccgggu gaccuacgac guggucuucc acggcuaccu ccccaacgag     2160

ggcgacagca agaacucccu gccguacggg aagaucaacg gcaccuacaa ggggacggag     2220

aaggagaaga ucaaguucag cuccgagggc agcuucgacc ccgacggcaa gaucgugucc     2280

uacgaguggg acuucgggga cggcaacaag agcaacgagg agaaccccga gcacuccuac     2340

gacaaggugg ggaccuacac cgucaagcug aaggugaccg acgacaaggg cgagagcucc     2400

gugagcacga ccaccgccga gaucaaggac cucuccgaga acaagcugcc cgucaucuac     2460

augcacgugc ccaagagcgg ggcccugaac cagaaggugg ucuucuacgg caagggcacc     2520

uacgaccccg acggguccau cgccggcuac cagugggacu ucggggacgg cagcgacuuc     2580

uccagcgagc agaaccccuc ccacguguac acgaagaagg gggaguacac cgugacccuc     2640

cgcgucaugg acagcagcgg ccagaugucc gagaagacca ugaagaucaa gaucacggac     2700

ccgguguacc ccaucggcac cgagaaggag cccaacaaca gcaaggagac cgccuccggg     2760

cccaucgugc cgggcauccc cgucagcggg accaucgaga acacguccga ccaggacuac     2820

uucuacuucg acgugaucac ccccggcgag gugaagaucg acaucaacaa gcugggguac     2880

ggcggcgcga ccugggucgu guacgacgag aacaacaacg ccgugagcua cgccaccgac     2940

gacgggcaga accuguccgg caaguucaag gccgacaagc ccgggcggua cuacauccac     3000

cucuacaugu ucaacggcag cuacaugccg uaccgcauca acaucgaggg guccgucggc     3060

cgguga                                                                3066


<210>  1097
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  1097
augaaguggg ugaccuucau cagccugcug uuccuguucu ccagcgccua cuccguccag       60

aacgagagca agcgcuacac cguguccuac cugaagacgc ucaacuacua cgaccuggug      120

gaccugcucg ucaagaccga gaucgagaac cugcccgacc uguuccagua cagcuccgac      180

gccaaggagu ucuacggcaa caagacccgg augagcuuca ucauggacga gaucgggcgc      240

cgggcgccgc aguacaccga gaucgaccac aagggcaucc ccacgcucgu ggaggugguc      300

cgcgccgggu ucuaccuggg cuuccacaac aaggagcuga acgagaucaa caagcggucc      360

uucaaggagc gcgugauccc cagcauccuc gccauccaga agaaccccaa cuucaagcug      420

gggaccgagg ugcaggacaa gaucgucucc gccaccggcc ugcucgccgg caacgagacc      480

gcgccgcccg agguggugaa caacuucacg cccauccugc aggacugcau caagaacauc      540

gaccgguacg cccuggacga ccucaagagc aaggcccugu ucaacguccu ggccgcgccc      600

accuacgaca ucaccgagua ccuccgcgcc accaaggaga agccggagaa cacgcccugg      660

uacgggaaga ucgacggcuu caucaacgag cugaagaagc uggcccucua cgggaagauc      720

aacgacaaca acuccuggau caucgacaac ggcaucuacc acaucgcgcc ccuggggaag      780

cugcacagca acaacaagau cggcaucgag acccucaccg aggugaugaa gguguacccc      840

uaccugucca ugcagcaccu ccagagcgcc gaccagauca agcggcacua cgacuccaag      900

gacgccgagg gcaacaagau cccgcucgac aaguucaaga aggaggggaa ggagaaguac      960

ugccccaaga ccuacacguu cgacgacggc aaggucauca ucaaggccgg ggcccgcgug     1020

gaggaggaga aggugaagcg gcuguacugg gccagcaagg aggucaacuc ccaguucuuc     1080

cgcguguacg gcaucgacaa gccccuggag gagggcaacc ccgacgacau ccucaccaug     1140

gugaucuaca acagcccgga ggaguacaag cugaacagcg uccuguacgg guacgacacc     1200

aacaacggcg ggauguacau cgagcccgag ggcaccuucu ucacguacga gcgggaggcc     1260

caggagucca ccuacacccu cgaggagcug uuccgccacg aguacaccca cuaccugcag     1320

gggcgguacg cggugcccgg ccaguggggc cgcacgaagc ucuacgacaa cgaccggcug     1380

accugguacg aggagggcgg ggccgagcug uucgccggga gcacccgcac cuccggcauc     1440

cucccccgca agagcaucgu guccaacauc cacaacacga cccggaacaa ccgguacaag     1500

cugagcgaca ccguccacuc caaguacggg gccagcuucg aguucuacaa cuacgccugc     1560

auguucaugg acuacaugua caacaaggac augggcaucc ugaacaagcu caacgaccug     1620

gcgaagaaca acgacgugga cggcuacgac aacuacaucc gcgaccuguc cagcaacuac     1680

gcccucaacg acaaguacca ggaccacaug caggagcgca ucgacaacua cgagaaccug     1740

accgucccgu ucguggccga cgacuaccug gugcggcacg ccuacaagaa ccccaacgag     1800

aucuacuccg agaucagcga ggucgccaag cugaaggacg cgaaguccga ggugaagaag     1860

ucccaguacu ucagcacguu cacccuccgc gggagcuaca ccggcggggc cuccaagggc     1920

aagcuggagg accagaaggc caugaacaag uucaucgacg acagccugaa gaagcucgac     1980

accuacuccu ggagcgggua caagacgcug accgccuacu ucaccaacua caagguggac     2040

agcuccaacc gggucaccua cgacguggug uuccacggcu accugcccaa cgagggcgac     2100

agcaagaacu cccuccccua cgggaagauc aacggcaccu acaaggggac ggagaaggag     2160

aagaucaagu ucagcuccga gggcagcuuc gacccggacg gcaagaucgu cuccuacgag     2220

ugggacuucg gggacggcaa caagagcaac gaggagaacc ccgagcacuc cuacgacaag     2280

guggggaccu acaccgugaa gcugaagguc accgacgaca agggcgagag cuccgugagc     2340

acgaccaccg cggagaucaa ggaccugucc gagaacaagc uccccgugau cuacaugcac     2400

guccccaaga gcggggcccu gaaccagaag gugguguucu acggcaaggg caccuacgac     2460

ccggacgggu ccaucgccgg cuaccagugg gacuucgggg acggcagcga cuucuccagc     2520

gagcagaacc ccagccacgu cuacacgaag aagggggagu acaccgugac ccugcgcgug     2580

auggacucca gcggccagau guccgagaag accaugaaga ucaagaucac ggaccccguc     2640

uacccgaucg gcaccgagaa ggagcccaac aacagcaagg agaccgccuc cgggcccauc     2700

gugcccggca ucccggugag cgggaccauc gagaacacgu ccgaccagga cuacuucuac     2760

uucgacguca ucacccccgg cgaggugaag aucgacauca acaagcucgg guacggcggc     2820

gccaccuggg uggucuacga cgagaacaac aacgcgguga gcuacgccac cgacgacggg     2880

cagaaccugu ccggcaaguu caaggccgac aagcccgggc gguacuacau ccaccuguac     2940

auguucaacg gcagcuacau gcccuaccgc aucaacaucg agggguccgu gggccgguga     3000


<210>  1098
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  1098
augaaguggg ugaccuucau cagccucuua uuccuguuuu ccagugccua cuccaugaag       60

cgcaagugcc ugagcaagcg gcucaugcug gccaucacca uggcgacgau cuucaccguc      120

aacuccaccc ugcccaucua cgccgccgug gacaagaaca acgccaccgc cgcgcgccgg      180

cgccggaagc gcgugcagaa cgagagcaag cgguacacgg ucuccuaccu caagacccug      240

aacuacuacg accuggugga ccuccuggug aagaccgaga ucgagaaccu gccggaccuc      300

uuccaguaca gcucagacgc caaggaguuc uacggcaaca agacccgcau gagcuucauc      360

auggacgaga ucgggcggcg cgcgccccag uacacggaga ucgaccacaa gggcauuccc      420

acccuggucg agguggugcg ggccggguuc uaccugggcu uccacaacaa ggagcucaau      480

gagaucaaca agcgcuccuu caaggagcga gucaucccaa gcauccuggc cauccagaag      540

aacccgaacu ucaagcuggg gaccgaggug caggacaaga ucguguccgc caccggccuc      600

cucgccggca acgagacggc cccgcccgag gucgugaaua acuucacccc cauccugcag      660

gacugcauca agaacaucga ccgcuacgcc cucgacgacc ucaagagcaa ggcgcuguuc      720

aacguccugg cagccccgac auacgacauc accgaguacc uccgggccac uaaggagaag      780

cccgagaaca cccccuggua cgggaagauc gacggcuuca ucaacgagcu gaagaaacuc      840

gcccuguacg ggaagaucaa cgacaacaac uccuggauca ucgacaacgg caucuaccac      900

aucgcgcccc uggggaagcu ccacagcaac aacaagaucg gcaucgagac cuugaccgag      960

gucaugaagg uguacccgua ccuguccaug cagcaccucc aaagcgccga ccagaucaag     1020

cgccacuacg acuccaagga cgccgagggc aacaagaucc cccuugacaa guucaagaag     1080

gaggggaagg agaaauacug ccccaagacg uacaccuucg acgacggcaa ggugaucauc     1140

aaggccgggg cccgggucga ggaggagaag gugaagcggu uauacugggc gucaaaagag     1200

gugaacagcc aguucuuccg ggucuacggc aucgacaagc cccucgagga gggcaacccg     1260

gacgacaucc ugaccauggu gaucuacaac ucccccgagg aguacaagcu gaacagcgug     1320

cucuacgggu acgacacaaa caacggcgga auguacaucg agcccgaggg cacguucuuc     1380

acguacgagc gcgaggccca ggaguccacc uacacccugg aggagcuguu ccggcacgag     1440

uacacgcacu accuccaggg gagauacgcc guccccggcc aguggggccg caccaagcug     1500

uacgacaacg accggcugac cugguacgag gagggagggg ccgagcuguu cgccgggagc     1560

acccgcacgu ccggcauccu gccgcgcaag agcaucguuu ccaacaucca uaacaccacc     1620

cggaacaaca gauacaagcu gagcgacacc guccacucca aguacggggc gagcuucgag     1680

uuuuacaacu acgccuguau guucauggac uacauguaca acaaggauau gggcauacuc     1740

aacaagcuga acgaccuggc caagaauaac gacguggacg gcuacgacaa cuacauccgc     1800

gaccugucaa gcaacuacgc ccucaacgac aaguaccagg accacaugca ggagcggauc     1860

gacaacuacg agaaccugac ggugcccuuc gucgcggacg acuaccuggu gcgucacgcc     1920

uacaagaacc ccaacgagau cuacucugag aucagugagg uggccaagcu caaggacgcc     1980

aagucagagg ucaagaaguc ccaguacuuc agcaccuuca cccugcgggg gagcuauacc     2040

ggcggggccu ccaagggcaa gcuggaggac cagaaggcca ugaacaaguu caucgacgac     2100

agccucaaga agcuggacac cuacagcugg uccggguaca agacgcugac cgcguacuuc     2160

accaacuaca agguggauag cuccaaccgc guaaccuacg acgucguguu ccacggcuac     2220

cuccccaacg agggcgacag caagaacucc cugccguacg ggaagaucaa cggcacguac     2280

aaggggaccg agaaggagaa aaucaaguuc agcuccgagg gcuccuucga ccccgacggc     2340

aagaucgugu ccuacgagug ggacuucggg gacggcaaca agagcaacga ggagaacccc     2400

gaacacuccu acgacaaggu cgggaccuac accgugaagc ugaaggugac ggacgacaag     2460

ggcgagagcu ccgucucuac caccaccgcc gagaucaagg accucuccga gaacaagcug     2520

cccgugaucu acaugcacgu gcccaaguca ggggcccuga accaaaaggu cguguuuuac     2580

ggcaagggca cguacgaccc cgacgggucc auagccggcu accaguggga cuucggggac     2640

ggcagcgacu ucagcuccga gcagaacccc agccacgugu acaccaagaa gggggaguac     2700

accgucaccc ucagggugau ggacuccagc ggccagaugu ccgagaagac gaugaagauc     2760

aagaucaccg auccggugua ccccaucggc accgagaagg agccgaacaa cagcaaggag     2820

accgcguccg ggcccaucgu cccgggcauc cccgugagcg ggacgaucga gaacaccucc     2880

gaccaggacu acuucuacuu cgacgugauc acccccggcg aggucaagau cgauaucaac     2940

aagcuggggu acggcggcgc caccugggug guguacgacg agaacaacaa cgccgucagc     3000

uacgcuacgg acgacgggca gaaccugucc ggcaaguuca aggccgacaa gcccgggcgg     3060

uacuacaucc accucuacau guucaacggc agcuacaugc cguaccggau caacaucgag     3120

ggguccguag gccgauga                                                   3138


<210>  1099
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  1099
augggcaccu ggauacuauu cgccugccuc cucggcgccg ccuucgccau gccccuaccc       60

ccccaccccg gccaccccgg cuacaucaac uucucauacg aaguccucac cccccucaaa      120

ugguaccaau caauccgccc ccccuacccc uccuacggcu acgaacccau gggaggcugg      180

cuccaccacc aaaucauccc cguccucucc caacaacacc cccccaccca cacccuccaa      240

ccccaccacc acauccccgu cguccccgcc caacaacccg ucauccccca acaacccaug      300

augcccgucc ccggccaaca cucaaugacc cccauccaac accaccaacc caaccucccc      360

ccccccgccc aacaacccua ccaaccccaa cccguccaac cccaaccaca ccaaccaaug      420

caaccccaac cccccgucca ccccaugcaa ccccuccccc cccaaccccc ccuacccccc      480

auguucccca ugcaaccccu cccccccaug cuccccgacc ucacccucga agccuggccc      540

uccaccgaca aaaccaaacg cgaagaaguc gacuaa                                576


<210>  1100
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  1100
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgaaguccuc       60

accccccuca aaugguacca auccauccgc ccccccuacc ccuccuacgg cuacgaaccc      120

augggcggcu gguaa                                                       135


<210>  1101
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  1101
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgaaguccuc       60

accccccuca aaugguacca auccauccgc ccccccccca ugcuccccga ccucacccuc      120

gaagccuggc ccuccaccga caaaaccaaa cgcgaagaag ucgacuaa                   168


<210>  1102
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  1102
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

caaaccuggg ccaugccccu ccccccccac cccggccacc ccggcuacau caacuucucc      120

uacgaagucc ucaccccccu caaaugguac caauccaucc gcccccccua ccccuccuac      180

ggcuacgaac ccaugggcgg cugguaa                                          207


<210>  1103
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  1103
auggccguca uggccccccg cacccucguc cuacuccucu ccggcgcccu cgcccucacc       60

caaaccuggg ccaugccccu ccccccccac cccggccacc ccggcuacau caacuucucc      120

uacgaagucc ucaccccccu caaaugguac caauccaucc gccccccccc caugcucccc      180

gaccucaccc ucgaagccug gcccuccacc gacaaaacca aacgcgaaga agucgacuaa      240


<210>  1104
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  1104
augggcaccu ggauccucuu cgccugccuc gucggcgccg ccuucgcaau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg aaguccucac cccacucaaa      120

ugguaccaau ccaugauccg cccacccuac ucauccuacg gcuacgaacc aaugggcggc      180

uggcuccacc accaaaucau ccccgucgua ucccaacaac acccccucac ccacacccuc      240

caaucccacc accacauccc cgucgucccc gcacaacaac cccgcguccg ccaacaagcc      300

cucaugcccg uccccggcca acaauccaug acccccaccc aacaccacca acccaaccuc      360

ccccuccccg cccaacaacc cuuccaaccc caacccgucc aaccccaacc ccaccaaccc      420

augcaacccc aacccccagu ccaacccaug caaccccucc ucccccaacc cccccucccc      480

cccauguucc cacuccgacc ccuccccccc auccuacccg accuccaccu ugaagccugg      540

cccgccaccg acaaaaccaa acaagaagaa gucgacuaa                             579


<210>  1105
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  1105
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgaaguccuc       60

accccccuca aaugguacca auccaugauc cgcccccccu acuccuccua cggcuacgaa      120

cccaugggcg gcugguaa                                                    138


<210>  1106
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  1106
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgaaguccuc       60

accccccuca aaugguacca auccaugauc cgcccccccc ccauccuccc cgaccuccac      120

cucgaagccu ggcccgccac cgacaaaacc aaacaagaag aagucgacua a               171


<210>  1107
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  1107
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

caaaccuggg ccaugccccu ccccccccac cccggccacc ccggcuacau caacuucucc      120

uacgaagucc ucaccccccu caaaugguac caauccauga uccgcccccc cuacuccucc      180

uacggcuacg aacccauggg cggcugguaa                                       210


<210>  1108
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  1108
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

caaaccuggg ccaugccccu ccccccccac cccggccacc ccggcuacau caacuucucc      120

uacgaagucc ucaccccccu caaaugguac caauccauga uccgcccccc ccccauccuc      180

cccgaccucc accucgaagc cuggcccgcc accgacaaaa ccaaacaaga agaagucgac      240

uaa                                                                    243


<210>  1109
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  1109
augggcaccu ggauccucuu cgccugucuc cucggcgccg ccuucuccau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg aaguccucac cccccucaaa      120

ugguaccaaa acaugauccg acaccccuac accuccuacg gcuacgaacc caugggcggc      180

uggcuccacc accaaaucau ccccgucguc ucccaacaaa ccccccaauc ccacgcccuu      240

caaccccacc accacauccc cauggucccc gcccaacaac ccggcauacc ccaacaaccc      300

augaugcccc ucccuggcca acacuccaug acccccaccc aacaccacca acccaaccuc      360

ccccuccccg cccaacaacc cuuccaaccc caacccgucc aaccccaacc ccaccaaccc      420

cuccaacccc aaucccccau gcaccccauc caaccccucc ucccccaacc accccuaccc      480

cccauguucu ccaugcaauc ccuccucccc gaccuccccc ucgaagccug gcccgccacc      540

gacaaaacaa aacgugaaga agucgacuaa                                       570


<210>  1110
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  1110
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgaaguccuc       60

accccccuca aaugguacca aaacaugauc cgccaccccu acaccuccua cggcuacgaa      120

cccaugggcg gcugguaa                                                    138


<210>  1111
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  1111
augccccucc ccccccaccc cggccacccc ggcuacauca acuucuccua cgaaguccuc       60

accccccuca aaugguacca aaacaugauc cgccaccccu cccuccuccc cgaccucccc      120

cucgaagccu ggcccgccac cgacaaaacc aaacgcgaag aagucgacua a               171


<210>  1112
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  1112
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

caaaccuggg ccaugccccu ccccccccac cccggccacc ccggcuacau caacuucucc      120

uacgaagucc ucaccccccu caaaugguac caaaacauga uccgccaccc cuacaccucc      180

uacggcuacg aacccauggg cggcugguaa                                       210


<210>  1113
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  1113
auggccguca uggccccccg cacccucguc cuccuccucu ccggcgcccu cgcccucacc       60

caaaccuggg ccaugccccu ccccccccac cccggccacc ccggcuacau caacuucucc      120

uacgaagucc ucaccccccu caaaugguac caaaacauga uccgccaccc cucccuccuc      180

cccgaccucc cccucgaagc cuggcccgcc accgacaaaa ccaaacgcga agaagucgac      240

uaa                                                                    243


<210>  1114
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  1114
augggcaccu ggauccucuu cgccugccuc cucggcgccg ccuucuccau gccccucccc       60

ccccaccccg gccaccccgg auacaucaac uucuccuaca uccgacaccc cuacaccucc      120

uacggcuacg aacccauggg cggcuggcuc caccaccaaa ucauccccgu cgucucccaa      180

caaacccccc aaucccacgc ccuccaacca caccaccaca uccccauggu ccccgcccaa      240

caacccggca ucccccaaca acccaugaug ccccuccccg gccaacacuc caugaccccc      300

acccaacacc accaacccaa ccucccccuu cccgcccaac aacccuucca accccaaccc      360

guccaacccc aaccccacca accccuacaa ccccaauccc ccaugcaccc cauccaaccc      420

cuccuccccc aacccccccu accccccaug uucuccaugc aaucccuccu ccccgaccuc      480

ccccucgaag ccuggcccgc caccgacaaa accaaacgcg aagaagucga cuaa            534


<210>  1115
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  1115
augggcaccu ggaucuucuu cgccugccuc cucggcgccu cccucgccau gccccuccca       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg aaguccucac accccucaaa      120

ugguaccaaa acaugauccg ccaccccuac accuccuacg gcuacgaacc caugggcggc      180

uggcuccacc accaaaucau ccccgucguc ucucaacaaa caccccaauc ccacgcccuc      240

caaccccacc accacauccc cauggucccc gcccaacaac ccggcauacc ccaacaaccc      300

augaugcccc uccccggcca acacuccaug acccccaccc aacaccacca acccaaccuc      360

ccccuccccg cccaacaacc cuuccaaccc caacccgucc aaccccaacc ccaccaaccc      420

cuccaacccc aaucccccau gcaccccauc caaccccuac ucccccaacc accccuacca      480

cccauguucu ccaugcaauc ccuccucccc gaccuccccc ucgaagccug gcccgccacc      540

gacaaaacca aacgcgaaga agucgacuaa                                       570


<210>  1116
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  1116
augggcaccu ggauccucuu cgccugccuc cucggcgccg ccuucuccau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg aaguccucac cccccucaaa      120

ugguaccaaa acaugauccg ccaccccucc cuccuccccg accucccccu cgaagccugg      180

cccgccaccg acaaaaccaa acgcgaagaa gucgacuaa                             219


<210>  1117
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  1117
augggcaccu ggauccucuu cgccugccuc cucggagccg ccuucuccau gccccuaccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg aagaccuuua ccucgaagcc      120

auccgcaucg accgcaccgc cuucguccuc accccccuaa aaugguacca aaacaugauc      180

cgccaccccu acaccuccua cggcuacgaa cccaugggcg gcuggcucca ccaccaaauc      240

auccccgucg ucucccaaca aaccccccaa ucccacgccc uccaacccca ccaccacauc      300

cccauggucc ccgcccaaca acccggcauc ccccaacaac ccaugaugcc ccuccccggc      360

caacacucca ugacccccac ccaacaccac caacccaacc ucccccuccc cgcccaacaa      420

cccuuccaac cccaacccgu acaaccccag ccccaccaac cccuucaacc ccaauccccc      480

augcacccca uccaaccccu ccucccccaa cccccccuac cccccauguu cuccaugcaa      540

ucccuccucc ccgaccuccc ccucgaagcc uggcccgcca ccgacaaaac caaacgcgaa      600

gaagucgacu aa                                                          612


<210>  1118
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  1118
augggaaccu ggauccucuu cgccugccuc cucggcgcag ccuucuccau gccccucccc       60

ccccaccccg gccaccccgg cuacaucaac uucuccuacg aaguccucac cccccuaaaa      120

ugguaccaaa acaugauccg ccaccccaca ccccaaucac acgcccucca accccaccac      180

cacaucccca ugguccccgc acaacaaccc ggcauccccc aacaacccau gaugccccuc      240

cccggccaac acuccaugac acccacccaa caccaccaac ccaaccuacc ccuccccgcc      300

caacaacccu uccaacccca acccguccaa ccccaacccc accaaccccu ccaaccccaa      360

ucccccaugc accccaucca accccuccuc ccccaacccc cccucccacc cauguucucc      420

augcaauccc uccuccccga ccucccacuc gaagccuggc ccgccaccga caaaaccaaa      480

cgcgaagaag ucgacuaa                                                    498


<210>  1119
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  1119
augccccuac ccccacaccc cggccacccc ggcuacauca acuucuccua cgaaguccuc       60

accccacuca aaugguacca aaacaugauc cgccaccccu acaccuccua cggcuacgaa      120

cccaugggcg gcuggcucca ccaccaaauc auccccgucg ucucccaaca aaccccacaa      180

ucccacgccc uccaacccca ccaccacauc cccauggucc ccgcccaaca acccggcauc      240

ccccaacaac ccaugaugcc ccuccccggc caacacucca ugacccccac ccaacaccac      300

caacccaacc uaccccuccc cgcccaacaa cccuuccaac cccaaccagu ccaaccccaa      360

ccccaccaac cccuccaacc ccaauccccc augcacccaa uccaaccccu acucccccaa      420

ccuccccuac cacccauguu cuccaugcaa ucccuccucc ccgaccuccc ccucgaagcc      480

uggcccgcca ccgacaaaac caaacgcgaa gaagucgacu aa                         522


<210>  1120
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  1120
augccaggag uugcccgccu accacuacua cuaggucucc ucuuacuccc gcgacccggc       60

cgcccacucg accuagcaga cuacacauac gaccucgcag aagaagacga cucagaacca      120

cuaaacuaca aagaucccug caaagccgcg gcauuccucg gagacauagc ccuggacgaa      180

gaagaucuac gagcauucca gguccaacaa gcaguagacc uccggcgaca cacagcucgc      240

aaaucgucca ucaaagcggc cgucccaggc aacacaagua ccccuuccug ccaguccacc      300

aacggucaac cccaacgggg agccugcgga cgcuggcgug gcaggucacg aucccggcga      360

gcagccacca gcagaccgga acgaguaugg cccgacgggg ucaucccauu cguaaucggu      420

gggaacuuca cgggaucgca acgagcagua uuccgacagg ccaugcgcca cugggaaaaa      480

cacacaugcg ucaccuuccu cgaacgcaca gacgaagaca gcuacauagu cuucacauac      540

agaccaugcg gaugcugcag uuacgucgga cggagaggcg gcggcccgca agcaauaucg      600

auagggaaaa acugcgacaa auucggcaua gucguccacg aacuagggca ugucguaggg      660

uucuggcacg agcacaccag gcccgaccga gaccgccacg uaagcauagu ccgcgaaaac      720

auccaacccg gacaggaaua caacuuccuc aagauggaac cccaagaagu cgagucgcug      780

ggggaaacau acgacuucga cuccauaaug cacuacgccc gaaacaccuu cagccgaggu      840

aucuuccucg acacaaucgu ccccaaguac gaagucaacg gcgucaaacc cccaauaggc      900

caacggaccc gacucucaaa aggugacauc gcucaggccc gcaaacugua uaagugcccc      960

gccugugggg agacccuaca ggacagcacg ggcaacuuca gcuccccuga auaccccaac     1020

ggcuacagcg cacacaugca cugcgucugg cgcaucagug ucaccccagg agagaaaauc     1080

auccucaacu ucaccucacu cgaucucuac cgaagcagac ucuguuggua cgacuacgug     1140

gagguccgag acggguucug gcgcaaagca ccgcuccgcg gccgcuucug cggcucuaaa     1200

cuucccgaac ccauugucag caccgacucg agacucuggg ucgaguucag gaguuccagc     1260

aacuggguag gcaaaggauu cuuugcaguc uacgaagcca uaugcggcgg cgacgucaag     1320

aaagacuacg gccacaucca guccccaaac uacccagacg acuaccgccc cuccaaaguc     1380

ugcauaugga ggauacaagu aucagaaggg uuucacgucg gacugacauu ccaaaguuuc     1440

gaaauagaac gucacgacuc augcgcguac gacuaccugg aaguacgcga cggccauucc     1500

gaaagcagca cacuaauagg ccgguacugu ggcuacgaaa agcccgacga cauaaaauca     1560

acaucaagca gacuguggcu aaaguucguc ucggacggaa gcauaaacaa agcaggauuc     1620

gcagugaacu ucuuuaagga agucgacgaa uguucgcgcc caaacagggg aggcugcgaa     1680

caaagaugcc uuaacacacu ggggucauau aagugcagcu gcgaccccgg auacgagcuu     1740

gcaccagaca agcgaagaug ugaggccgcc ugcggaggcu uccucacaaa acugaacgga     1800

uccaucacau cacccggaug gccaaaagag uaucccccga auaaaaacug cauauggcag     1860

cuaguagcgc caacccaaua ccggaucagc cuccaguucg acuucuucga aaccgaaggc     1920

aacgacgugu gcaaauacga cuucgucgag guacgcagcg gucuuaccgc ggacucaaaa     1980

cugcacggca aauucugcgg cagcgaaaaa ccagaaguaa ucaccagcca auacaacaac     2040

augagagucg aauuuaaauc agacaacacc guauccaaga aaggcuucaa agcccacuuc     2100

uuuuccgaua aagacgaaug caguaaagau aacgggggcu gucagcaaga cugcguuaac     2160

acauucggaa gcuacgaaug ucaaugccgc aguggguucg ugcugcacga caacaaacac     2220

gacugcaaag aagcaggaug cgaccauaaa gucaccagca caagcggaac gaucacuagc     2280

cccaacuggc cggacaaaua cccauccaag aaagaaugca caugggccau cuccagcacc     2340

cccggccacc gcgucaaauu aacauucaug gagauggaca ucgaaucaca acccgaaugc     2400

gccuacgacc accuggaggu auucgacggc cgagacgcca aagcaccagu gcucggccgc     2460

uucugcggcu ccaagaaacc agaaccagug cuagccaccg gcagucgaau guuccuccgc     2520

uucuacagug acaacagugu acaacgaaaa ggauuccaag caagccacgc aacagaaugc     2580

gguggccaag uccgggccga cgucaaaaca aaagaccuau acucacaugc ucaauucggu     2640

gacaacaacu acccgggcgg uguagacugc gaauggguca ucgucgcaga agagggauac     2700

ggggucgaac ucguguucca aacauucgaa gucgaggaag agacagauug uggcuacgac     2760

uacauggaac ucuucgacgg guacgacagc accgccccca gacuaggccg cuacugugga     2820

ucagguccac ccgaagaagu cuacagcgcc ggugacucag uacucgugaa auuccacagc     2880

gacgacacaa uuacaaagaa aggcuuccac cuaagauaca cguccaccaa auuccaggac     2940

acccuccaca gccgcaaaug a                                               2961


<210>  1121
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  1121
auggucgccg gcacccguug ccuccuugcc cuccuccuac cccaaguccu acuaggcgga       60

gcagccggcc ucguccccga acucggccgc cgcaaauucg ccgccgccuc auccggacgc      120

cccuccucac aacccagcga cgaaguacuc ucagaauucg aacuucgucu acucuccaug      180

uucggccuca aacaacgacc cacucccucc cgcgacgcag ucgucccccc uuacaugcua      240

gaccuuuacc gccgccacuc cggccaaccc ggaucacccg cccccgacca ucgccucgaa      300

agagccgccu cccgagccaa uaccguccgc ucauuccacc acgaagaauc acucgaagaa      360

cuacccgaaa ccagcggaaa aacaacacgc agauucuucu ucaaccucuc cagcaucccc      420

accgaagaau ucaucaccuc cgccgaacua caaguauuca gagaacaaau gcaggacgcc      480

cucggcaaca acuccagcuu ccaccaccgc aucaacauau acgaaauaau caaacccgcc      540

acagcuaacu ccaaguuccc cgucacacgc cuacucgaca cccgccuagu caaccaaaau      600

gccucccgcu gggaauccuu cgacgucacc cccgccguca ugcgauggac cgcacaaggc      660

cacgccaauc acggcuucgu cguagaaguu gcacaccuag aagaaaaaca aggcgucucc      720

aaacgccacg uccgcaucuc cagaucccua caccaagacg aacacucaug gucccaaauc      780

cgcccccucc uagucaccuu cggacaugac ggcaaaggac acccgcucca caaacgcgaa      840

aaacgccaag ccaaacacaa acaacgcaaa cgccucaaau cauccugcaa acgccaccca      900

cucuacguag acuucuccga cguaggaugg aacgacugga uagucgcacc cccaggcuac      960

cacgcauucu acugccacgg agaaugccca uucccacuug ccgaccaccu caacuccacc     1020

aaccacgcua ucguacaaac acucgucaac uccgucaacu caaaaauccc aaaagcaugc     1080

ugcgucccca cagaacucuc agccaucucc augcucuacc ucgacgaaaa cgaaaagguc     1140

guccuaaaaa acuaccaaga cauggucguc gaaggcugcg gcugccgcua g              1191


<210>  1122
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  1122
augauaccgg gcaaccgcau gcucaugguc guucuccugu gccaaguccu acucggcggc       60

gcaagccacg ccucacucau ccccgaaacu gggaaaaaaa aagucgccga aauccaaggc      120

cacgccggcg gaagacgcuc cggccaauca cacgaacucc uccgcgacuu cgaagccacc      180

cuacuacaaa uguucggccu ccgccgccgc ccacaacccu caaagagcgc cgucaucccc      240

gacuacaugc gcgaccuaua ccgacuccaa uccggcgaag aagaagaaga acaaauccac      300

uccaccggac ucgaauaccc cgaacgcccc gccucccgag caaacaccgu acguucuuuc      360

caccacgaag aacaccucga aaauaucccc ggcaccuccg aaaacuccgc auuccgcuuc      420

cuauucaacc ucuccuccau ccccgaaaac gaaguaaucu cauccgcaga acuccgccua      480

uuccgcgaac aagucgacca aggccccgac ugggaaagag gcuuccaccg aauaaacauu      540

uacgaaguca ugaaaccccc agccgaaguc guacccggcc accucaucac acgacuucuc      600

gacacacgcc uaguccacca uaacguaacu cgcugggaaa ccuucgacgu aagccccgcc      660

guccuccgau ggacccguga aaaacagccc aacuacggcc ucgcaauuga agucacccac      720

cuccaccaaa cacgcacaca ccaaggccaa cauguccgca uaucccgauc acucccacaa      780

ggcuccggca acugggccca acuccgucca cuccucguua ccuucggcca ugacggacgc      840

ggucacgccc ucaccagacg ccgcagggcc aaacgauccc ccaaacauca cucccagcgc      900

gcucguaaaa aaaacaaaaa cugccgccgc cauucccuau acguagacuu cuccgacguc      960

ggcuggaacg acuggauagu cgcacccccc ggauaccaag ccuucuacug ccacggcgac     1020

ugccccuucc cacucgcaga ccaccuaaac ucaaccaauc acgccaucgu acaaacccuc     1080

guaaacucag ucaacuccuc cauucccaaa gccugcugcg uacccaccga acuauccgcc     1140

aucuccaugc ucuaccuaga cgaauacgac aaagucgucc ucaaaaacua ccaagaaaug     1200

gucgucgaag gcugcggcug ccgauag                                         1227


<210>  1123
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  1123
augcccgggc uaggccgacg agcacaaugg cuaugcuggu gguggggccu acuaugcuca       60

ugcugcggac caccuccccu acgcccaccc cugcccgcag ccgcugccgc agcugccggc      120

ggccaacuac uaggcgacgg cggcucaccc ggccgaacag aacaaccccc ucccucuccc      180

caauccucau ccggauuccu auaccgcaga cucaaaaccc aagaaaaacg cgaaaugcaa      240

aaagaaaucc uaucaguacu cggccugcca cauagaccca gaccccucca cggacuccaa      300

caaccccaac cucccgcccu gcgucaacaa gaagaacaac aacaacaaca gcaacuaccc      360

cgcggcgaac ccccacccgg ccgccuaaaa ucagcacccc uauuuaugcu cgaccuuuac      420

aacgcccucu cugccgacaa ugaugaagac ggcgccuccg aaggugaacg ccaacaaucc      480

uggccccacg aagccgccuc aucaucacaa cgacgacaac ccccacccgg cgccgcccac      540

ccacucaacc gaaaaucccu ucucgccccc ggaucugguu ccgggggcgc uuccccacuc      600

accuccgcac aagacagcgc cuuccuaaac gacgccgaca ugguuauguc auucguaaac      660

cuagucgaau acgacaaaga auuuucaccc agacaaagac accauaaaga guucaaauuc      720

aaccucuccc aaaucccaga aggcgaaguc guaacagccg ccgaguuccg aaucuacaaa      780

gacugcguca ugggauccuu caaaaaccaa accuuccuaa uaagcaucua ccaaguacua      840

caagaacacc aacaccguga cuccgaccuc uuucuucuag acacccgagu agucugggcc      900

ucagaagaag guuggcuuga guucgacauc accgccacca gcaaccuaug gguagucaca      960

ccccaacaca acaugggacu gcaacuauca gucguaaccc gcgacggcgu acacguucac     1020

ccccgagcag ccggacucgu aggucgcgac ggacccuacg acaaacaacc cuucaugguc     1080

gccuucuuua aagucuccga aguacacguc cgaacaacac gauccgcauc aucccgccgc     1140

cgccagcaau cccggaaccg aucaacacaa ucccaagacg ucgcccgcgu cagcucggcu     1200

ucggacuaca acuccagcga acuaaaaaca gcaugccgca aacacgaacu auacgucucc     1260

uuucaagacc ucggauggca agacuggauc aucgcaccca aaggauacgc agcaaacuac     1320

ugcgacggag aaugcuccuu cccccuaaau gcacacauga acgcaaccaa ccacgccauc     1380

guccaaaccc ucguccaccu aaugaacccc gaauauguac ccaaacccug cugcgcccca     1440

accaaacuaa acgcaaucuc aguacucuac uucgacgaca acuccaacgu aauccucaag     1500

aaauaccgca acaugguugu ccgugccugc ggaugccacu aa                        1542


<210>  1124
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  1124
augcacgucc gaucacuacg cgccgcagcc ccacacuccu ucguagcacu cugggcaccc       60

cuauucuuac uccgcuccgc acuagccgac uucucccucg acaacgaagu ccacucgagc      120

uucauccacc gccgccuacg gucccaagaa agacgcgaaa ugcaacgcga aauccucuca      180

auucuaggac ucccccaccg cccccgcccc caccuccaag gcaaacacaa cucugccccc      240

auguucaugc ucgaccucua caacgccaug gcaguagaag aaggaggcgg acccggcggc      300

caaggcuucu cauaccccua caaagccguu uucucaaccc aaggcccgcc ccucgcaucc      360

cuccaagacu cacacuuccu aaccgacgcc gacaugguaa ugucauucgu caaccucgua      420

gaacaugaca aagaauucuu ccacccccgc uaucaccacc gcgaauuccg auucgaccuc      480

ucgaaaauac ccgaaggcga agccgugacc gcagccgaau uccgcauaua caaagacuac      540

auccgcgaac gcuucgacaa cgaaacauuc cgcaucuccg ucuaccaagu gcuccaagaa      600

caccucggcc gcgaaagcga ccucuuccua cuugacuccc gcacacuuug ggccucugaa      660

gaagguuggc ucguauucga cauaacagcc accucaaacc acuggguagu caacccccgu      720

cacaaccuag gacuccagcu aucaguagaa acacucgacg gccagagcau caaccccaaa      780

cuugcgggac ucaucggccg ccacggacca caaaacaagc agcccuucau ggucgccuuc      840

uuuaaagcca ccgaaguaca uuucagaucc auacgcucca ccggguccaa acaacgauca      900

caaaaccgau ccaaaacccc aaaaaaccaa gaagcucuac gaauggcaaa cguagcugaa      960

aacagcuccu cagaccaacg ccaagccugc aaaaaacacg aacucuacgu cuccuuccga     1020

gaccucggcu ggcaagacug gaucaucgcc ccagaaggcu acgcagcaua cuacugcgaa     1080

ggcgaaugcg ccuucccccu uaacucuuac augaacgcca ccaaccacgc aaucguccag     1140

acccucguac acuucaucaa ccccgaaacu guccccaaac ccugcugcgc ccccacccaa     1200

uuaaacgcaa ucuccguccu cuacuucgac gacuccucga acgucauacu caaaaaauac     1260

cgaaacaugg ucguccgcgc cugcggcugc cauuaa                               1296


<210>  1125
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  1125
augaaagccu ccgccgcccu ccucugccuc cuccucaccg ccgccgccuu cuccccccaa       60

ggccuagccc aacccgucgg caucaacacc uccaccaccu gcugcuaccg auucaucaac      120

aaaaaaaucc ccaaacaacg ccucgaaucc uaccgccgca ccaccuccuc acacugcccc      180

cgcgaagccg ucaucuucaa aaccaaacuc gacaaagaaa ucugcgccga ccccacccaa      240

aaaugggucc aagacuucau gaaacaccuc gacaaaaaaa cccaaacccc caaacucuaa      300


<210>  1126
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  1126
augcugcuca cgcugaucau cuuauuaccg gucgucagua aauuuagcuu uguaucacug       60

agcgcacccc aacacugguc augcccagag ggcacuuugg cagggaacgg caauucgacg      120

ugcguaggac cagccccauu ccugaucuuc agccacggaa auagcaucuu ccgaaucgac      180

acagaaggaa cgaacuauga gcaacucgua gucgacgcag ggguaucggu uaucauggac      240

uuccauuaca acgagaaaag aauauacugg gucgaccuag aacgacagcu ccugcaaagg      300

guauuccuga acggcucgcg gcaggaacgg guaugcaaca uagagaaaaa cgucagcggc      360

auggccauaa acuggaucaa cgaagaagug aucuggucca accaacagga aggcaucaua      420

accgucacug acaugaaagg aaacaacagc cacauccucc uaucagcgcu aaaguacccc      480

gccaaugucg cggucgaccc aguagaacgg uucauuuucu gguccuccga aguagcuggg      540

agccuuuacc gcgcagaccu agacggcguc ggaguaaaag cacuacuuga aacauccgag      600

aaaauaacag caguaucccu ugacguccua gacaagcgcc ucuucuggau acaauacaau      660

cgcgaagggu cuaacagccu caucugcagu ugugacuaug acggcgggag cguacacauc      720

ucaaaacacc caacacaaca uaaucuauuc gcgaugagcc ucuucgguga cagaauauuc      780

uacucaaccu ggaagaugaa aacaauaugg auagccaaca aacacacagg caaagacaug      840

guccgcauca accuccacag cuccuucgua ccccucggcg aacuaaaagu agugcacccc      900

cuagcccagc ccaaagccga agaugauacg ugggaacccg aacaaaagcu gugcaaacug      960

cgcaaaggga acugcagcag uaccguuugc ggucaagacu uacagucuca ccucugcaug     1020

ugcgcugagg gguacgcccu uucgagagac agaaaauacu gcgaggacgu caacgaaugc     1080

gccuuuugga accacggcug cacacuuggc ugcaaaaaua caccgggaag cuacuacugc     1140

acaugucccg uaggauucgu ccuucuaccc gauggaaagc gcugccacca acuggucucg     1200

uguccucgca acgucucgga augcagccau gacugcguac uaaccuccga agguccacua     1260

ugcuucugcc cagaggguuc aguucuagag cgggacggca agacaugcag uggaugcuca     1320

uccccagaca acggcggaug cucccaacua ugcgucccac ugagcccggu cucaugggaa     1380

ugcgacugcu ucccugggua cgaccuccag cuugaugaaa aaucaugcgc ugccuccggg     1440

ccccagcccu uccuacucuu cgccaacucg caagacauaa gacauaugca cuucgacggc     1500

acagauuacg ggacccugcu gucccaacag augggcaugg uauacgcacu cgaccacgac     1560

ccaguggaaa auaaaaucua uuucgcccac acagcccuua aguggaucga acgcgccaac     1620

auggacggca gccaaagaga acggcucaua gaagaggggg uggacgugcc agagggccuc     1680

gcugucgacu ggauagggcg ccgguucuac uggacagacc ggggcaaaag ccucauaggc     1740

agaucagacc ucaacgggaa aaggagcaag aucauaacga aagagaauau cucgcaaccc     1800

cgcggaaucg ccguccaccc aauggcaaaa agacuauucu ggacagauac gggaauaaac     1860

ccccggaucg agagcuccuc ccuacaaggg cucgggcggu uaguaaucgc cuccagcgac     1920

cuaauauggc ccagcgggau uaccaucgac uuccuaacag acaaacucua cuggugcgac     1980

gcaaaacaau ccgucaucga aauggccaau cuagacggua gcaaacgacg ccgacucaca     2040

caaaacgacg uaggccaucc cuuugcgguc gccgucuucg aggacuacgu cugguucucu     2100

gauugggcca ugcccucagu caugcgaguc aacaagcgca cgggaaagga ucgagugagg     2160

cuccagggcu cgauguugaa accaagcagc cuaguagucg uccacccacu ggcaaaacca     2220

ggcgcagacc caugccuaua ccagaacggg ggcugugagc acaucuguaa aaagagacua     2280

ggaaccgcau ggugcucaug cagggaaggg uucaugaaag cguccgacgg caaaaccugc     2340

cuugccuuag acggacacca acuccuagca ggaggcgaag uugaccuuaa aaaccaagua     2400

acgccguuag auauccucag caaaacaagg guaagcgagg auaacaucac cgagucacag     2460

cacaugcucg uggcagaaau uaugguguca gaccaagacg acugcgcacc cguaggcugc     2520

ucuauguacg caagaugcau auccgaaggc gaagacgcca caugccagug ccugaagggc     2580

uuugccgggg acgguaaacu gugcuccgac auagaugagu gcgaaauggg aguacccguc     2640

uguccgcccg caagcuccaa augcauaaac acagaaggcg gauacgugug ccggugcuca     2700

gaaggauacc aaggcgacgg aauccacugc cuggacaucg acgaaugcca guuaggugaa     2760

cauucgugcg gggaaaacgc cuccugcacu aacaccgaag gaggcuacac augcaugugc     2820

gccggacguc ugagcgaacc cgggcuaaua ugccccgacu ccacaccacc cccacacuug     2880

cgcgaggacg accaccauua cagcguacgg aacagcgaca gcgaaugccc ccuaucacac     2940

gacggcuacu gcuuacacga cggcgucugc auguacaucg aagcccuaga caaauacgcg     3000

ugcaacugcg ugguagguua cauaggugag cguugccaau accgagaccu uaaauggugg     3060

gaacuacgcc acgccggaca cggccaacag cagaagguca ucgucgucgc aguaugcguc     3120

guaguccucg ucaugcuucu acuccuauca cuauggggcg cacacuacua cagaacucaa     3180

aaauuauuaa gcaagaaccc caaaaauccg uacgaggaau ccagcagaga uguccgcagc     3240

cggagaccgg cggacacgga ggacggcaug uccucgugcc cgcaacccug guucgucguc     3300

aucaaagaac accaagaccu gaagaacggc ggccaacccg uagcaggaga agacggacaa     3360

gccgccgacg gaagcaugca accgaccucg uggcgacaag aaccccagcu augcggcaug     3420

ggcacugagc agggcugcug gauuccagua aguagugaca aagguagcug cccacagguc     3480

auggagcgau ccuuccauau gccuucuuac ggaacacaaa cacuagaagg cgguguagaa     3540

aagccgcauu cucuccuguc cgcaaacccg cucuggcaac aacgagcacu agauccaccc     3600

caccaaaugg aacucaccca auaa                                            3624


<210>  1127
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  1127
augaccgccg gccgccgcau ggaaaugcuc ugcgccggcc gcguccccgc acuccuccuc       60

ugccucggcu uccaccuccu ucaagccguc cucuccacca ccgucauccc cuccugcauc      120

cccggcgaau ccuccgacaa cugcaccgcc cuaguccaaa ccgaagacaa cccacgcguc      180

gcccaagucu ccaucacaaa augcuccucc gacaugaacg gcuacugccu ccacggccaa      240

ugcaucuacc ucgucgacau gucccaaaac uacugccgcu gcgaagucgg cuacaccggc      300

guccgcugcg aacacuucuu ccucaccguc caccaacccc ucuccaaaga auacgucgcc      360

cucaccguca uccucaucau ccucuuccuc aucaccgucg ucggcuccac cuacuacuuc      420

ugccgcuggu acagaaaccg caaauccaaa gaacccaaaa aagaauacga acgcgucacc      480

uccggcgacc ccgaacuccc ccaagucuaa                                       510


<210>  1128
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  1128
auggccgaag gcgaaaucac caccuucacc gcccucaccg aaaaauucaa ccuccccccc       60

ggcaacuaca aaaaacccaa acuccucuac ugcuccaacg gcggccacuu ccuccgcauc      120

cuccccgacg gcaccgucga cggcacccgc gaccgcucag accaacacau ccaacuccaa      180

cucuccgccg aauccgucgg cgaaguauac auaaaaucca ccgaaaccgg ccaauaccuc      240

gccauggaca ccgacggccu ccucuacggc ucccaaaccc ccaacgaaga augccucuuc      300

cucgaacgcc ucgaagaaaa ccacuacaac accuacaucu ccaaaaaaca cgccgaaaaa      360

aacugguucg uaggccucaa aaaaaacggc uccugcaaaa gaggcccccg cacccacuac      420

ggccaaaaag ccauccucuu ccucccacuc cccgucucau cagacuaa                   468


<210>  1129
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  1129
augguggggg uagggggagg ggacguggag gacguaacgc cgaggccggg agggugucag       60

auaagcggga gaggggcgag agggugcaac ggaauaccgg gagcggcggc gugggaggcg      120

gcgcugccga ggaggaggcc gaggaggcac ccgagcguaa acccaagaag cagagcagca      180

gggagcccga ggacgagggg gagaaggacg gaggagaggc cgagugggag caggcugggg      240

gaucggggga gggggagagc acugccggga gggcgacuag ggggaagagg gagggggagg      300

gcgccggaga gggugggagg gagggggagg gggaggggga cggcggcgcc gagagcggcg      360

ccggcggcga gggggagcag gccgggaccg gcggggacga uggcagcggg gagcauaacc      420

acguugccgg cgcugccgga agauggaggg aguggggcgu ucccaccggg gcacuucaag      480

gauccgaaga gacuguauug uaagaaugga ggguucuuuc uaaggauaca uccggauggg      540

agaguggaug gggugaggga aaagagugac ccgcacauaa agcugcaguu gcaggcggag      600

gagagagggg uaguaagcau aaagggggug ugcgcaaaua gguaucuggc gaugaaggag      660

gaugggaggc uauuggcgag caagugugug acggacgagu gcuuuuucuu ugaaaggcua      720

gagagcaaua acuacaacac guacaggagc agaaaguaua cgagcuggua uguggcgcug      780

aagagaacgg gacaguacaa guuagggagc aagacagggc cagggcagaa ggcaauauug      840

uuccugccaa ugagugcaaa gagcuag                                          867


<210>  1130
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  1130
augcacaaau ggauccucac cuggauccuc cccacccucc ucuaccgcuc cugcuuccac       60

aucaucugcc ucgucggcac caucucccuc gccugcaacg acaugacccc cgaacaaaug      120

gccacaaacg ucaacugcuc cucccccgaa cgccacaccc gcuccuacga cuacauggaa      180

ggcggcgaca uccgcguccg ccgacucuuc ugccgcaccc aaugguaccu acgcaucgac      240

aaacgcggca aaguaaaagg cacccaagaa augaaaaaca acuacaacau cauggaaauc      300

cgcacagucg ccgucggcau agucgcaauc aaaggcgucg aauccgaauu cuaccucgcc      360

augaacaaag aaggcaaacu cuacgccaaa aaagaaugca acgaagacug caacuucaaa      420

gaacucaucc ucgaaaacca cuacaacacc uacgccuccg ccaaauggac ccacaacggc      480

ggcgaaaugu ucgucgcccu caaccaaaaa ggcauccccg uccgcggcaa aaaaaccaaa      540

aaagaacaaa aaaccgccca cuuccucccc auggccauca ccuaa                      585


<210>  1131
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  1131
augaaacucc uccccuccgu aguccucaaa cuauuccucg cagccguccu auccgcccuc       60

gucaccggcg aaucacucga acgccuccgc cgcggccucg ccgcaggcac aagcaacccc      120

gaccccccca ccgucuccac cgaccaacuc cucccccuag gcggcggccg agaccgcaaa      180

guccgcgacc uccaagaagc agaccucgac cuccuccgcg ucacccucuc cuccaaaccc      240

caagcccuag caacccccaa caaagaagaa cacggcaaac gaaaaaaaaa aggcaaagga      300

cuaggcaaaa aacgcgaccc cugccuccgc aaauacaaag acuucugcau ccacggcgaa      360

ugcaaauacg ucaaagaacu acgcgccccc uccugcauau gccaccccgg cuaccacggc      420

gaacgaugcc acggccuauc ccuccccgua gaaaaccgac uauacaccua cgaccacacc      480

accauccucg ccgucgucgc cgucguccuc ucauccgucu gccuacucgu aaucguagga      540

cuccucaugu uccgcuacca ccgccgaggc ggcuacgacg ucgaaaacga agaaaaaguc      600

aaacucggca ugaccaacuc ccacuaa                                          627


<210>  1132
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  1132
auguggguca cuaaacuacu ccccgcccuc cuacugcaac acguucuccu ccaccuauua       60

cugcucccca uugcaauccc auacgccgaa ggccagcgaa aacgccgcaa cacgauccac      120

gaauuuaaga aaagcgcaaa aacaacccua aucaaaauag acccugcacu aaaaauaaaa      180

accaagaaag ucaacacagc agaccaaugc gcuaacagau gcacccggaa caaaggccug      240

ccguucacau gcaaggcauu cgucuucgac aaggcccgca aacaaugccu gugguuccca      300

uucaacucaa ugagcucagg cgucaagaaa gaguucggac acgaguucga ccucuacgaa      360

aacaaagacu acauccgcaa cuguaucauc ggaaaaggaa gauccuacaa aggcacagua      420

ucaaucacca aguccggcau caaaugccaa cccuggagca gcaugauccc ccacgaacac      480

uccuuccucc ccagcucgua ccgcggcaaa gaccuccaag aaaacuacug ccggaacccc      540

cgaggagaag aaggcggucc cuggugcuuc accuccaacc ccgaaguccg cuacgaaguc      600

ugcgacaucc cccaaugcag cgaaguagaa ugcaugaccu gcaacggcga auccuacaga      660

ggccuaaugg aucacaccga auccggcaag auaugccaac gcugggacca ucaaacccca      720

caccgccaca aguuccuacc cgaacgcuac cccgacaaag gauucgacga caacuacugc      780

cgcaacccug acgggcaacc acgccccugg ugcuacaccc uagacccaca cacacgaugg      840

gaauacugcg ccaucaaaac cugcgccgau aacacaauga acgacacuga cgucccacua      900

gaaaccaccg aaugcauaca aggacaaggc gaagguuaca gaggaaccgu aaacacuaua      960

uggaacggca uaccuugcca acgcugggac ucccaauacc cacacgaaca cgacaugacu     1020

cccgaaaacu ucaaaugcaa agaccuccgc gaaaacuacu gccgcaaucc cgaugggucc     1080

gaaagucccu ggugcuucac cacagaccca aacauccgcg ugggauacug cucccaaauu     1140

cccaacugcg acaugucuca cggucaagac ugcuaccgag gcaacggcaa gaacuacaug     1200

ggaaaccugu cacagaccag auccggucua accugcucca ugugggacaa aaacauggaa     1260

gaccuccaca ggcacauauu cugggaaccc gacgccucca agcucaauga aaacuacugc     1320

aggaaccccg acgacgacgc ccacggcccc ugguguuaca caggaaaccc ccucauuccu     1380

ugggacuacu gcccaauauc acgcugcgaa ggugacacua cacccacaau agucaaccuc     1440

gaccaccccg ucaucucuug cgccaaaaca aaacaacuca ggguagucaa cggaaucccc     1500

accaggacaa acauaggcug gauggucucc cuacgguacc gcaacaaaca caucugcgga     1560

ggcucacuga ucaaagaauc cuggguccuc accgcacgcc aaugcuuccc cagcagagac     1620

cucaaagacu acgaagccug guuagguauu cacgacgucc acggcagagg ggacgaaaaa     1680

ugcaagcaag uccucaacgu aagccagcuc gucuacggac ccgaaggauc ggaccucgua     1740

cucaugaaac uggcccgccc cgcaguacuc gacgacuucg ucucaacgau ugaccugcca     1800

aacuacggau gcacgauccc agaaaagacg ucauguagcg ucuacgguug gggcuacacg     1860

ggccucauca acuacgacgg ccuccuccga gucgcacacc uuuauaucau gggcaacgaa     1920

aaaugcagcc agcaccaccg aggcaaaguc acacuuaacg aauccgaaau cugugcagga     1980

gccgagaaaa uaggcucagg acccugcgaa ggcgacuacg gcggaccccu ggucugcgaa     2040

caacacaaaa ugcgcauggu ccuuggcguc aucguacccg gacgaggcug cgccaucccc     2100

aaccgccccg gcauauucgu cagaguugca uacuaugcaa aauggaucca uaaaaucaua     2160

cuaacauaca aaguccccca gucauaa                                         2187


<210>  1133
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  1133
auggcaaaag cagcagcaau aggcaucgac cuaggaacca ccuacucaug cgucggaguc       60

uuccagcacg gcaaaguaga aauaaucgcu aacgaccaag gaaacagaac cacgcccucg      120

uacgucgccu ucaccgacac cgaacgacug auaggggacg cagcaaagaa ccaggucgca      180

cucaacccac aaaauacagu cuucgacgca aaaagacuca uaggcagaaa auucggcgac      240

cccguagugc aaagcgacau gaaacacugg ccauuccaag ugauaaacga cggggacaaa      300

ccaaaagucc aagucucaua caaaggcgaa acaaaggcau ucuacccaga agaaaucucc      360

agcauggucu uaaccaaaau gaaagaaaua gccgaagcau accucgguua cccaguaacg      420

aacgcaguca uuacaguacc cgcauacuuc aacgacagcc aacggcaagc cacgaaagac      480

gcgggaguca uagcagggcu caacguauua agaauaauca acgaaccaac agcagcagcc      540

aucgcauacg gccuggaucg cacaggcaag ggcgaaagaa acguacugau cuuugaccua      600

ggcgggggca cguucgacgu aagcauccug accauagacg acgggauuuu cgaggucaaa      660

gcaacagcag gggacacaca ccugggcggg gaagacuucg acaacagacu cgugaaccac      720

uucguagaag aguucaaacg caaacacaag aaagacaucu cgcagaacaa aagagcagug      780

agaagacuac ggaccgcgug cgagcgcgca aaacgcaccc uaagcucaag cacgcaggcg      840

agccuggaaa uagacagccu cuucgaagga aucgacuucu acacaucuau aacaagagcg      900

agauucgaag aacugugcuc cgaccucuuc cgcuccacgc uggagccagu cgaaaaagcg      960

cuccgggaug cgaaacugga caaagcacaa auccaugacc ucguacuggu cggaggcucg     1020

acccgcauuc caaaagugca aaaacuccuc caggacuucu ucaacggacg agaccucaac     1080

aaaucaauca accccgacga agcagucgcg uacggggccg cuguccaagc cgcaauccug     1140

augggggaca aaagcgagaa ugugcaagac cuccuccucc ucgacguggc cccacucucg     1200

cuuggacucg agaccgcggg aggcguaaug acagcacuca uaaaaagaaa uucaacaauc     1260

ccaacaaagc agacacagau cuucacaacg uauagcgaca aucaaccggg cguacucaua     1320

caaguauacg agggcgaacg cgcaaugacg aaggacaaca accuucuagg cagauucgag     1380

cucucaggca uaccaccagc cccacgcggg guaccgcaaa uagaagugac auucgacauc     1440

gacgcaaacg gaaucuuaaa cguaacagcg accgauaaau caaccggaaa ggcgaacaaa     1500

aucacaauca caaacgacaa aggacgccuu ucaaaagaag agaucgagag aaugguacag     1560

gaggcagaaa aguacaaagc agaggacgag guccaacgcg aaagaguauc cgccaaaaac     1620

gcccuggaau cauacgcauu caacaugaag uccgccgucg aagacgaagg ucuaaaggga     1680

aagauauccg aagccgacaa aaagaaagua cuagauaaau gccaagaagu caucagcugg     1740

cucgacgcaa acaccuuggc cgaaaaagac gaauuugaac acaaaagaaa agaacuugaa     1800

caaguaugca aucccauaau cucaggccug uaccaaggcg caggcgggcc agggcccggg     1860

ggcuuugggg cacaaggccc caaaggagga agcggaagcg ggccgacaau agaggaagua     1920

gacuaa                                                                1926


<210>  1134
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  1134
auggcgaaag cagcagcaau cggaaucgac cucgguacca cauacagcug cguaggcgua       60

uuccaacacg ggaaaguaga aaucauagca aacgaccaag ggaaccggac aacccccucc      120

uacgucgccu ucaccgacac agaacgacuu aucggcgacg cagccaaaaa ccaggucgcc      180

uuaaaccccc aaaacaccgu cuucgacgca aaaagacuca ucggaagaaa auucggggac      240

cccgugguac aaagcgacau gaaacacugg cccuuccaag uaaucaacga cggagauaag      300

cccaaggucc aaguaucgua caaaggcgag accaaagccu ucuacccaga agaaauauca      360

agcauggugu uaaccaagau gaaggaaauc gccgaagccu accucggcua cccagugaca      420

aacgccguaa uaaccgugcc cgcguacuuc aaugacuccc aacgccaagc cacgaaagac      480

gccggcguca uagccggacu aaacguacua cgcauaauaa augaaccgac agcagccgcc      540

aucgcauacg gacucgaccg cacaggcaaa ggcgaaagaa acguauugau auucgacuua      600

ggcggaggca ccuucgacgu cucgauacua accauagacg acggaauauu cgaggucaag      660

gccaccgccg gagacacaca ccuaggcggc gaagacuucg auaaucgucu agugaaccac      720

uucguagaag aguucaagcg caaacacaag aaagacaucu cccaaaacaa acgugcagug      780

cgaaggcuaa gaaccgcaug cgaacgcgca aaaagaaccc ucagcuccag cacacaagcg      840

agccuagaaa uagacagucu cuucgaaggc aucgauuucu acaccucgau aacuagagcg      900

cgcuucgaag aauuaugcag cgacuuauuc cgaucgacau uagaaccugu agaaaaagcg      960

cuccgggacg cgaaacuaga caaagcccaa auccacgacu ugguccuggu agggggcucu     1020

acaaggauac cgaaagugca aaagcuauua caagacuucu ucaacggacg cgaucucaau     1080

aaauccauca accccgacga ggcaguagca uacggcgccg cgguccaggc agcgauacuc     1140

augggagaca aaucagaaaa cgugcaagac cuccugcucc uugacguagc accacucucg     1200

cucggacuag aaacggcggg aggggucaug accgcacuca ucaagagaaa caguaccauc     1260

ccaaccaaac aaacccaaau cuucaccaca uacucagaca accaaccggg agugcuaauc     1320

caaguauacg aaggcgaacg cgcgaugacc aaagacaaua accugcuagg aagauucgaa     1380

cuaucaggca uacccccggc uccacgaggc gucccccaaa ucgaaguaac cuucgacaua     1440

gacgccaacg gaauccucaa cgugacagcg accgacaaaa gcaccgggaa agcaaacaaa     1500

aucacaauca caaacgacaa aggacgauua agcaaagaag agaucgagcg aaugguccaa     1560

gaagccgaaa aguacaaagc cgaagacgag guccaacgcg aacgaguaag cgccaaaaac     1620

gcauuagaau ccuacgcguu caauaugaaa agcgcaguag aagacgaagg acugaaaggg     1680

aaaauaagcg aagcagacaa aaagaaagua cucgacaaau gccaagaagu aaucuccugg     1740

cuagacgcaa auacccucgc cgaaaaagac gaguucgaac acaaaagaaa agaacuggaa     1800

caagugugca acccaauuau cucaggacua uaccaggggg caggcgggcc aggacccgga     1860

ggauucggcg cgcaaggacc aaaaggaggc agcggaagcg gaccaacaau cgaggaagua     1920

gacuaa                                                                1926


<210>  1135
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  1135
auggcgacag caaagggcau agcaauaggc aucgaccucg gcaccacaua cuccugcgua       60

ggcgucuucc aacacggcaa aguagaaauc aucgcaaacg accaaggaaa caggacaaca      120

cccucauacg ucgcauuuac cgacaccgaa agacuuaucg gagacgcggc caaaaaccag      180

gucgcaauga acccccaaaa uaccgucuuc gacgcaaagc gacucauagg acgcaaauuc      240

aaugaccccg ugguacaggc agacaugaaa cuauggccgu uccaaguuau aaacgaaggc      300

ggaaagccga aaguccucgu auccuacaaa ggcgaaaaca aagccuucua ccccgaggaa      360

aucucgagca ugguccuaac caaacucaaa gaaacagccg aagcauuccu cgggcaccca      420

gucaccaacg cggucauaac cguaccagca uacuucaacg acucgcaaag acaggcaacc      480

aaagacgccg gagucaucgc aggacugaac guccuccgaa ucaucaacga accaaccgcc      540

gcagccaucg ccuacggacu agacaaaggc gggcaaggcg aacggcacgu acuuaucuuc      600

gaccucgggg gcggaaccuu cgacgucucc auccugacca ucgacgaugg gauauucgaa      660

gucaaagcca cggccggaga cacacaccuc ggaggcgaag acuucgacaa ccgccuagua      720

agucacuucg ucgaagaguu caaacgaaaa cacaaaaagg acaucagcca gaacaaacga      780

gcaguacgcc gccucaggac agcaugcgaa cgcgccaaaa ggacacuaag cuccuccacg      840

caagcaaacc ucgaaauaga cagccuauac gaaggaauag acuucuacac aagcaucaca      900

agggccagau ucgaagaacu cugcgcagac cuauuccggg gcacacucga accagucgaa      960

aaagcgcugc gagacgccaa gauggacaaa gccaaaaucc augacauagu ccucgucgga     1020

ggcuccaccc gaauccccaa aguacaacga cuucuacagg auuacuucaa cggaagagau     1080

cucaauaaau caaucaaccc cgacgaggcg gucgcauacg gcgccgccgu gcaggccgca     1140

auacucaugg gggacaaaag cgagaaagua caagaccugu uacuacugga uguggcaccc     1200

cuaagccucg ggcuggaaac cgccggaggg gucaugaccg cccucaucaa acgaaacucc     1260

acgaucccca caaaacaaac ccaaauauuc accaccuacu ccgacaacca gccaggagua     1320

cuaauccaag uauacgaagg agaacgcgcc augacaaaag acaacaaccu acuaggccgg     1380

uucgaucuaa caggcauacc accggcgccc cgagggguac cccaaaucga aguaacauuc     1440

gacaucgacg ccaacggcau acugaacgug accgcaacgg acaaaucgac cgggaaagug     1500

aacaaaauaa caaucacaaa cgacaagggc cgcuuaagca aggaagaaau cgagcgcaug     1560

guccuagacg cagaaaaaua caaagccgaa gacgaaguac aacgagagaa aaucgccgcg     1620

aagaacgcgc uggaaagcua cgcauucaac augaaaagcg uaguaucaga cgagggacua     1680

aaaggcaaaa uaagcgaaag cgacaaaaac aaaauacucg acaaaugcaa cgaacuacua     1740

agcuggcuag aagucaauca acucgccgaa aaagaugagu ucgaccacaa acgcaaggaa     1800

cucgaacaaa ugugcaaccc aauaaucacc aaacuuuacc aaggaggcug cacaggccca     1860

gcaugcggaa caggcuacgu accaggccga ccugccaccg gccccaccau agaagaagua     1920

gacuag                                                                1926


<210>  1136
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  1136
augagugcgc gcggacccgc aaucggaaua gaccucggca ccaccuacuc augcgugggc       60

guauuccagc acggaaaagu cgaaauaauc gcaaacgacc aagggaacag aaccacacca      120

uccuaugugg ccuuuacuga caccgaacgc cuaaucggag acgcugccaa gaaccaggua      180

gcaaugaacc ccacaaacac aaucuucgac gcaaagaggc uaaucggacg caaguucgaa      240

gacgcaacag uccaaagcga caugaagcac uggcccuucc gcguaguauc cgaaggaggc      300

aaacccaagg uccaagucga auacaaaggc gagacaaaga ccuuuuuccc agaagagauc      360

ucaagcaugg uacucaccaa aaugaaagaa auagcggagg cauaucuugg aggaaagguc      420

cacagcgcag ugauaacagu ccccgcauac uuuaacgaca gccaaagaca agcaacaaaa      480

gacgcaggaa ccauaacagg acuuaacguc cuccgaauaa ucaaugaacc aacagcagca      540

gcaaucgcau acggccuaga caagaaaggc ugcgccggag gcgagaaaaa cguccuaaua      600

uucgaccuag gcgggggaac guucgacguc ucaauacuca ccauagaaga cggcaucuuc      660

gaggucaaaa gcacggccgg agacacacac cucggcgggg aagacuucga caaccgcaug      720

gugagccauc ucgccgaaga guucaaaaga aagcacaaga aagauauagg ccccaacaaa      780

cgggcaguga gaaggcucag gaccgcaugc gaacgggcga aaagaacccu cagcucaagc      840

acacaagcaa guauugaaau cgacucccua uacgaagggg uagacuucua caccucaauc      900

acacgggccc gcuuugagga acuaaacgcc gaucuguucc gcggaacacu agaaccaguc      960

gaaaaagcac uccgagacgc aaaauuagac aaaggccaaa uucaagaaau aguccugguc     1020

ggagguucca cccgcauccc aaaaauccaa aaacuacuac aagacuucuu caacgggaaa     1080

gaacucaaca aaucaauuaa ccccgaugaa gcagucgccu acggagcagc aguacaagca     1140

gcgauacuca ucggggacaa aagcgagaac guccaagacc uacuacugcu agacgugacc     1200

ccacucucac ucgggauaga gacagcaggc ggaguaauga ccccacugau aaaacgaaac     1260

acaaccauac ccacaaaaca gacccagacc uucacaaccu acagcgacaa ccagucaucc     1320

guacucgucc agguguacga gggagaacga gcaaugacga aagacaacaa ccuauugggc     1380

aaguucgacc uaacgggcau accgcccgcg ccccgcggug uaccacaaau cgaagucacu     1440

uuugacauag acgccaacgg aauccuaaac gugaccgcgg ccgacaaaag cacagggaag     1500

gaaaacaaga ucacaauaac aaacgacaaa gggagacuga gcaaagacga cauugaccga     1560

augguccaag aagcagaacg cuacaaaucu gaagaugagg caaacagaga ccgagucgcu     1620

gcaaagaacg cacuggaauc uuacaccuac aacaucaagc agaccgucga agacgaaaaa     1680

cugcgaggaa aaauaagcga acaagacaaa aacaaaauac uggacaaaug ucaagaaguc     1740

auaaacuggc ucgaccgaaa ccaaauggcc gaaaaagacg aauacgaaca caaacaaaaa     1800

gaacucgaac gaguaugcaa ccccauaauc ucaaaauuau accaaggagg cccaggaggc     1860

gggagcggcg gaggaggcuc cggagcgagc ggaggcccca ccaucgaaga aguagauuaa     1920


<210>  1137
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  1137
augucggucg uaggaaucga ucugggcuuu caaucaugcu acguugcagu ggcgagagca       60

ggaggaaucg aaaccauagc caacgaauac agcgauaggu guacgccggc augcaucagc      120

uucggcccca aaaacagauc aauaggagca gccgccaaau cacaagucau cuccaacgca      180

aagaacaccg uacaaggcuu caagcgauuc cauggcagag ccuuuucgga cccguucguc      240

gaagcugaaa aauccaacuu agcguacgac auaguucaac ucccaacagg auuaaccggc      300

aucaaaguca ccuacaugga agaggagcga aacuuuacca ccgaacaggu aaccgcgaug      360

cuccuaagca agcuaaagga aaccgcagaa agcguccuca aaaagcccgu cguagauugc      420

guggucuccg ucccaugcuu cuacacggac gcagaacguc gcagcguaau ggacgccaca      480

caaauagccg gacucaacug ccuacggcug augaacgaaa cgaccgcagu cgcacuggcc      540

uacgggauau auaagcaaga ccuaccagcg cuggaagaaa aaccacguaa cguggucuuc      600

gucgacaugg gacacuccgc cuaccaaguc uccgugugcg cguucaaccg cggcaaacuc      660

aaaguccucg caacagcguu cgauaccaca uugggcggac gcaaguucga ugaaguacuc      720

guaaaccacu ucugcgagga guucggcaaa aaguacaaac ucgacaucaa aucgaaaaua      780

cgagcacuac uccgccuuag ccaagaaugu gaaaaacuaa agaaacugau gucagcaaac      840

gccagcgacc uaccacuauc aauagaaugc uucaugaacg acguagacgu aagcggaacg      900

augaaucgcg gaaaauuccu ggaaaugugc aacgaccucc ucgcccgagu ugagccgcca      960

cuacggagcg ugcucgaaca aaccaagcuc aagaaagaag acauauacgc cguagaaaua     1020

gucgggggcg caacccgcau ccccgccgug aaagagaaaa ucucaaaauu cuucgggaaa     1080

gaacucagca ccacacucaa cgccgacgaa gcggugaccc gaggcugcgc gcuccaaugc     1140

gcaauccuaa gccccgccuu caaaguacga gaguucucca uaaccgacgu aguccccuau     1200

cccauauccc uuagguggaa uagccccgca gaagaaggca gcagcgacug cgaaguauuc     1260

agcaaaaacc acgccgcacc cuucucaaaa guacugaccu ucuaccgaaa agaaccauuc     1320

acacucgagg cauacuacag cuccccacag gaccucccau acccagaccc ggccaucgcc     1380

caauucagcg uacaaaaagu cacaccacaa agcgacggua gcucgagcaa agucaaggua     1440

aaaguccggg ucaacguuca cggcauauuc ucaguaagca gcgcaagccu cguagaagua     1500

cacaaauccg aggaaaacga agaacccaug gaaaccgacc aaaacgccaa agaagaagag     1560

aaaaugcaag uagaucaaga ggaaccacac gucgaggaac aacagcaaca gacccccgcc     1620

gaaaacaaag cagaaagcga agaaauggaa accagccaag ccggcuccaa agauaagaaa     1680

auggaccaac caccacaagc caaaaaggcc aaagucaaaa cauccacagu cgaucucccc     1740

auagaaaacc aacuacuaug gcaaaucgac cgcgagaugc ucaacuuaua cauagagaau     1800

gaaggcaaaa ugauaaugca agacaaacuc gaaaaagaga gaaacgacgc caaaaacgca     1860

gucgaagaau acgucuacga aaugcgagac aaacuaagcg gcgaauacga gaaauucgua     1920

ucggaagacg acagaaacag cuucacccua aagcuggagg acaccgaaaa cuggcuauac     1980

gaagacggag aagaccaacc caaacaagua uacguagaca aacucgcaga acucaaaaac     2040

cuaggccaac ccaucaaaau acgauuccaa gaauccgagg aacgccccaa auuauucgaa     2100

gaacucggca agcaaaucca acaguacaug aaaauaauau cgagcuucaa aaacaaagaa     2160

gaccaauacg aucaccugga cgcagcagac augacuaaag uagaaaaauc aacaaacgaa     2220

gcaauggaau ggaugaacaa caaacucaac cuucaaaaca agcaaagccu uaccauggac     2280

ccaguaguca aaagcaagga aaucgaagcc aagaucaaag agcucacauc aaccuguucc     2340

ccuaucauau caaaacccaa accaaaagua gaaccaccca aggaagaaca gaaaaacgcc     2400

gaacaaaacg gccccgucga cggacaaggc gacaaccccg gcccccaagc cgccgaacaa     2460

gggaccgaca ccgcaguacc aagcgacagc gauaagaaac uucccgaaau ggacaucgac     2520

uag                                                                   2523


<210>  1138
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  1138
augucagucg ucggcaucga ucucggguuc cugaacugcu acauagcagu cgcccggagu       60

ggagggaucg agacaauagc aaacgaauac ucggaccgcu gcacacccgc augcauaagc      120

cucggcucca gaacgagagc caucgguaac gccgcuaaga gccaaaucgu aaccaacgua      180

cgcaacacaa uccacggcuu uaagaaacuc cacggcagau cguuugacga cccuauaguc      240

cagacagagc gcauacgacu gcccuacgaa cuacagaaaa ugccaaacgg gagcgcgggc      300

gucaaagucc gauaccuaga agaggagcgc ccauucgcaa uugaacaagu aacuggaaug      360

cugcuagcaa aauuaaaaga aacgagcgaa aacgcccuaa agaaacccgu agccgauugc      420

guuaucucaa uaccgagcuu uuucacagac gcagagcggc gcucagucau ggccgcagcc      480

caagucgccg gccucaacug ccuccgccuc augaacgaaa caacugccgu ugcccuggcc      540

uacggcaucu acaaacaaga ccuaccgccc cuggacgaga aaccgcgaaa cgucgucuuu      600

aucgacaugg gacacuccgc auaccaaguu cuaguaugcg ccuucaacaa aggcaagcuc      660

aaaguacugg caaccacauu cgaccccuac cucgguggac gaaacuucga ugaagcgcuc      720

gucgacuacu ucugcgacga guucaaaacg aaauacaaaa ucaacgucaa ggagaacucc      780

cgggcccugc uaagacucua ccaagagugc gaaaaacuaa agaaacuuau gucggcaaac      840

gccucagacc ugccccucaa cauagaaugu uucaugaaug accucgacgu aagcuccaaa      900

augaaccgcg cacaauucga gcaacuaugc gccagccugc uagccagggu agaaccucca      960

cuaaaagcag ucauggagca ggcuaaccua caacgcgagg acauaagcag caucgagauc     1020

gugggaggcg ccacacgcau acccgcaguc aaagaacaaa ucaccaaauu uuuccuaaaa     1080

gacaucucaa ccacccucaa cgccgacgaa gcaguagcgc gcggcugcgc ccuccaaugc     1140

gcgauacuca gcccagccuu caagguacgc gaguucagua ucaccgaccu cguccccuac     1200

ucaauaacac uaagauggaa aaccucguuc gaagacggcu ccggagaaug cgaaguauuc     1260

ugcaagaauc acccggcacc guucucgaag guaaucaccu uccacaagaa agaacccuuc     1320

gaacuugaag cauucuacac aaaucuucac gagguaccau acccggacgc acgcauaggc     1380

ucauucacca uccaaaacgu cuucccccaa uccgacggcg acucaagcaa agugaaagug     1440

aaaguccgcg uaaauaucca cggaauauuc uccguagcaa gcgcaucagu aaucgagaaa     1500

caaaaccucg aaggcgacca cagcgacgca ccaauggaga ccgaaaccag cuucaagaac     1560

gagaacaagg acaauaugga caaaaugcaa guagaccagg aagaaggaca ccagaaaugc     1620

cacgcagaac acacccccga ggaagaaauc gaccacacag gcgccaaaac aaaauccgcc     1680

guaagcgaca aacaggaucg ccuaaaccag acgcucaaaa aggggaaagu gaaauccaua     1740

gaccuaccca uccaguccuc acuuugccgc cagcuaggcc aggaccuucu gaacucauac     1800

aucgaaaacg aggggaaaau gaucaugcaa gacaaacucg aaaaggaaag gaaugacgcc     1860

aaaaacgcag ucgaagaaua cguauacgac uuccgcgacc gacugggcac aguauacgaa     1920

aaauucauua cacccgaaga ccucaguaag cuaagcgcgg ucuuggagga caccgagaac     1980

uggcucuacg aagacggcga ggaccagccc aaacaaguau acguggacaa acuacaagaa     2040

cucaaaaagu acggacaacc uauccaaaug aaguacaugg aacacgaaga acgcccaaaa     2100

gcucuaaacg accuaggcaa gaagauacag cucguaauga aggucaucga agccuaccgc     2160

aacaaagacg aaagauacga ccaccuagac ccaaccgaaa uggaaaaagu agaaaaaugc     2220

auaagcgaug caaugagcug gcucaacucu aagaugaaug cacaaaacaa acucucccuu     2280

acccaagacc cagucguaaa agucucagaa auugucgcga aaagcaaaga gcuagacaac     2340

uucugcaauc ccaucaucua caagcccaaa cccaaagcag aaguacccga agacaaaccc     2400

aaagccaacu ccgaacacaa cggcccgaug gacggccaaa gcggaaccga aacaaagucc     2460

gacaguacca aagacagcuc gcagcacacc aaguccuccg gcgaaaugga agucgacuaa     2520


<210>  1139
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  1139
augaaacuaa gccuggucgc agcaaugcug cuacuacuaa gcgcagcaag ggcagaggaa       60

gaagacaaga aagaggacgu cggcacagua gucggaauag accuggggac gaccuacagc      120

uguguagggg ucuucaagaa cggcagaguu gaaaucaucg caaacgacca aggcaaccga      180

auaacaccga gcuacguagc guucacaccc gaaggcgaaa gacucaucgg ggacgcagcc      240

aaaaaccaac uaacaagcaa cccggaaaac acaguguucg acgccaaaag acuaaucggc      300

agaaccugga acgaccccuc cguccaacaa gacauaaaau uccucccauu caaaguggua      360

gaaaagaaaa cgaaacccua cauacaaguc gacauagggg gcgggcagac aaaaacauuc      420

gcgccagaag aaaucagcgc aaugguccua accaaaauga aagaaacggc agaagcguac      480

cugggaaaga aagucaccca cgccgucguc acgguccccg ccuacuucaa cgacgcgcaa      540

cgacaagcaa ccaaagacgc aggcacgauc gcgggacuga acguaaugag gauaaucaac      600

gaaccaacag cagccgccau cgcauacgga cuggacaagc gcgaaggaga gaaaaacaua      660

cuggucuucg accugggcgg aggaacauuc gacgucucgc uacugacaau agacaacggc      720

guauucgagg ucguggcuac gaacggagac acacaccuag gaggggaaga cuucgaccaa      780

cgagucaugg aacacuucau aaaacuauac aagaagaaaa ccggaaaaga cguaagaaaa      840

gacaacagag ccguacaaaa acugaggcgc gaaguagaaa aagcgaaacg ggcccugagc      900

ucgcaacacc aagcgagaau agaaauagag uccuucuacg aaggagaaga cuucagcgaa      960

acacuaacgc gcgccaaauu cgaagaacuc aacauggacc ucuuccgcuc aacuaugaag     1020

cccguccaaa aagugcucga agacagcgac cugaaaaaga gcgauaucga cgaaauagua     1080

cugguaggcg gaagcacacg gaucccaaaa auacagcaac ucgugaaaga guucuucaac     1140

ggaaaagaac caucgcgagg gaucaaccca gaugaagcgg ucgcauacgg ugcagcgguc     1200

caggccgggg uacuaagcgg agaccaagac acaggagauc ugguacuccu ugacgugugc     1260

ccacuaaccc ucgggauaga gaccguaggc ggcguuauga caaaacugau cccccgcaac     1320

accguaguac ccacgaagaa aagccaaauc uucagcacgg caagcgacaa ccaaccgacc     1380

guaaccauaa aaguguauga gggggaacga ccccucacga aagacaacca ccuacucggc     1440

acauucgacc ucacaggaau accaccagcc ccgcgcggag uaccacaaau cgaaguaacg     1500

uucgaaaucg acgugaacgg aauccuacgc gucaccgccg aggacaaagg gaccggcaac     1560

aagaacaaaa ucaccaucac gaacgaccaa aaccgccuca caccggagga aaucgaacgu     1620

auggucaacg acgcggaaaa guucgcggaa gaggacaaga aacucaaaga acgcauagac     1680

acgcgaaacg aacuggaauc auacgcauac ucacugaaaa accaaauagg agacaaggaa     1740

aagcuaggag gcaagcuauc gagcgaggac aaagaaacaa uggaaaaggc agucgaggag     1800

aaaauagaau ggcuagaauc ccaccaagac gcagacauag aagacuucaa agcgaaaaag     1860

aaagaguuag aagaaaucgu ucaaccaauc aucagcaaac uauacgguag cgcaggccca     1920

ccgccuacag gcgaggaaga uaccgcagaa aaagacgagc uguag                     1965


<210>  1140
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  1140
augcaagccc cacgagagcu agcaguagga auagaccucg gaacuacaua cucaugcgua       60

ggcguauucc aacaaggacg cguagaaaua cucgcaaacg accaaggcaa ccgcaccacg      120

ccaagcuacg ucgccuuuac cgacaccgag agacucguag gcgacgcagc caaaucgcag      180

gccgcccuca auccccacaa caccgucuuc gacgcgaaaa gacuaaucgg ccgaaaauuc      240

gccgauacca caguccaaag cgacaugaaa cacuggcccu uucgcguagu gucagaagga      300

ggaaaaccaa aagucagggu cugcuaccga ggagaagaca aaaccuucua cccagaagag      360

auaucgagua ugguacuauc caaaaugaag gaaaccgcag aagccuaccu aggacaacca      420

guaaagcacg ccgucauaac aguaccagcg uacuucaacg acagccaaag acaagccacc      480

aaggacgccg gggccauagc cggacuaaac guccuccgca uaaucaacga accgaccgcu      540

gccgcgaucg cauacggccu cgaccgcagg ggagcuggcg aaagaaacgu ccucaucuuc      600

gaccucggag ggggaacauu cgacgucuca guacuaagua uagacgccgg cguauuugaa      660

guaaaagcca cagcaggcga cacccaccua ggaggagaag acuucgacaa ccgacucgug      720

aaccacuuca uggaagaguu ccgacgcaaa cacggcaaag accucuccgg caacaaacgg      780

gccuugagac gacucagaac agccugcgaa agagcaaaaa gaacacucag cucaagcaca      840

caagcgacau uagaaauaga cucccuauuc gagggcguag acuucuauac cucgaucaca      900

cgcgcaagau ucgaggaacu gugcucagac cucuucagau caacccucga accggucgag      960

aaagcucuaa gagacgccaa acuagacaaa gcacaaaucc acgacgucgu cuuaguaggc     1020

ggaagcaccc gaauaccaaa agugcaaaaa cuccuacaag acuucuucaa cggaaaggag     1080

cucaacaagu caauaaaccc cgacgaagcc gucgcauacg gggccgcagu acaggccgca     1140

gugcucaugg gcgauaaaug cgagaaaguc caagaccuuc uacuacucga cguagcccca     1200

cuuucccuag ggcucgaaac cgcgggcggg guaaugacca cccucaucca acgaaacgca     1260

acaauaccaa cuaaacaaac ccagaccuuc acaacauacu cagacaauca accgggagua     1320

uucauacaag ucuacgaagg cgaacgagcc augacaaaag acaacaaccu ucucggcagg     1380

uuugaacuca gcggcauacc cccagcccca cgcggcgucc cacaaauaga agucaccuuc     1440

gauauagacg ccaacggcau acucagcgua acggcaaccg accgcagcac cggaaaagcg     1500

aacaagauaa ccaucacaaa cgacaaaggg cgccuaagca aagaagaggu cgagcgcaug     1560

guccaugaag cagaacagua uaaagcagag gacgaagccc aacgagacag aguagcagcg     1620

aaaaacaguc ucgaggcaca cguguuccac gucaaaggcu cacuacaaga agagagccua     1680

cgagacaaaa uccccgaaga agacaggcgg aaaaugcaag auaaaugccg cgaaguacuc     1740

gcuuggcucg agcacaacca acuggccgaa aaggaggaau acgaacacca aaaacgagaa     1800

cucgagcaga uaugccgacc cauauucucc cgccucuacg gcggccccgg cguccccgga     1860

ggaagcagcu gcggcacgca agccagacaa ggagaccccu caaccggacc cauaaucgaa     1920

gaaguggacu aa                                                         1932


<210>  1141
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__P48741__HsHSPA7

<400>  1141
augcaagccc cccgcgaacu agccguaggc aucgaccucg gcacaaccua cagcuguguc       60

ggcguauucc aacaaggcag aguagaaauc cuagccaacg accaaggcaa cagaacgacc      120

ccaucauacg ucgcguucac cgacacagaa aggcuaguag gagacgcagc aaaaucccaa      180

gcagcccuaa acccgcacaa cacuguauuc gacgccaaac gccuaaucgg acgaaaauuc      240

gcagacacaa ccguccaauc agacaugaaa cacuggccau uccaagucgu cuccgaaggu      300

ggaaaaccca aaguacgagu augcuaccga ggggaagaca aaacauucua cccagaagaa      360

auaagcucaa ugguacuaag caaaaugaaa gaaaccgcgg aagccuaccu aggccaacca      420

guaaaacacg ccguaaucac ggucccgacc uacuucagca acucccagag acaggccacc      480

aaagacgcag gagcaaucgc aggccuaaaa guacucccaa ucauaaacga agccacagcc      540

gcagcaauag ccuacggccu ggaccgaaga ggagccggca aacgaaacgu acucauauuc      600

gaccuaggag gaggaacauu cgacguaucc guacucucga ucgacgccgg ggucuucgaa      660

guaaaagcua ccgccggcga cacccaccua ggaggcgaag acuucgacaa ccgccuaguc      720

aaccacuuca uggaagaauu ccgcagaaaa cacggcaaag accuaagcgg aaacaaacga      780

gcccucagac gacuccgaac agccugcgaa cgagccaaac gcaccccauc aagcagcacc      840

caggccacac uagaaaucga cucccuauuc gaaggcguag acuucuacaa aagcaucacc      900

agagccagau ucgaagaacu cugcagcgac cuauuccgaa gcacccuaga acccguggaa      960

aaagcccucc gcgacgccaa acuagacaaa gcacaaaucc acgacuucgu acuaggcggc     1020

gggcuccaca gccacccaca aggcgcagaa gucgccgcag gccuacucca acgacaaggc     1080

gcagaacaag aacaccagcc auaa                                            1104


<210>  1142
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  1142
augucaaaag gacccgcagu gggaaucgac cuaggcacca ccuacucaug cguaggcguc       60

uuccaacacg gaaaagucga gauaaucgcc aacgaccaag gaaacaggac gacaccauca      120

uauguagccu ucaccgacac cgagcgccua auaggagacg ccgccaaaaa ccaggucgca      180

augaacccaa cgaacaccgu auucgacgcc aaacgacuaa ucggccgccg auucgacgau      240

gcagucgucc agagcgacau gaaacacugg cccuucaugg uaguaaacga cgccggccga      300

ccaaagguac aagucgaaua caaaggcgaa accaaauccu ucuaccccga agaggugucc      360

agcauggucc ucaccaaaau gaaagaaaua gcagaagcgu accuggggaa aacagucacc      420

aacgcaguag ucaccguccc cgcauacuuc aacgacagcc agagacaagc aacaaaagac      480

gcaggcacca ucgccgggcu aaacguccua cgcauaauca acgaacccac agcagcugca      540

aucgcauacg gucucgacaa gaaaguuggu gccgaacgca acguccuaau cuucgaccuc      600

gggggcggca ccuucgacgu aucaauccuc acaauagaag acggaauauu cgaagucaaa      660

agcaccgcag gcgacaccca ccuaggcggc gaggacuucg acaacagaau gguaaaccac      720

uucaucgcag aguucaaacg gaaacacaag aaagacaucu ccgaaaacaa acgcgcagua      780

cgacgccuac ggacagcaug cgaacgcgcc aaacgcaccc ucuccuccuc cacccaagca      840

agcauagaaa ucgacagccu auacgaagga auagauuucu acacauccau cacaagggcg      900

cgcuucgaag aacuaaacgc agaccucuuc cgagguaccc ucgacccagu cgaaaaagca      960

uuaagagacg caaaacuaga caaaagccaa auccacgaca uaguccuggu gggcggauca     1020

acccguaucc cuaaaaucca aaaacuacua caggacuucu ucaacggaaa agaacuaaac     1080

aaguccauca acccagacga agcuguggca uacggcgcgg ccguacaagc cgccauccua     1140

agcggcgaca aaucggaaaa cgugcaggac cugcuacucc uagacgucac accccucuca     1200

cuaggcauag aaaccgcggg cggcguaaug accguccuaa uaaaacgaaa cacaaccaua     1260

ccaaccaaac aaacgcaaac cuucacaaca uacagcgaca accaaccagg gguacucauc     1320

caaguauacg aaggcgaacg cgcaaugacc aaagacaaca accuccuagg caaauucgaa     1380

cuuacaggaa ucccacccgc accccgaggg guaccccaaa uagaaguaac auuugacaua     1440

gacgccaacg gcauccuaaa ugucagcgcc gucgacaaaa gcaccggaaa agaaaacaaa     1500

auaacgauaa ccaacgacaa aggccgacug agcaaagaag acaucgagcg aaugguacaa     1560

gaagccgaaa aauacaaagc agaggaugaa aaacagcgcg acaaaguauc aagcaaaaac     1620

agucuggaaa gcuacgccuu caacaugaaa gcaacagugg aagacgaaaa acuccaaggc     1680

aagaucaaug acgaagacaa gcagaaaauc cucgacaaau gcaacgaaau caucaacugg     1740

cucgacaaga accaaacagc agaaaaggaa gaguucgaac accaacagaa agaacucgaa     1800

aaagucugca accccauaau cacaaaacug uaccaauccg caggcggaau gcccggcggc     1860

augcccggag gauucccagg cggcggggca ccacccagug gcggagccag cucaggaccg     1920

acaaucgaag aaguagacua a                                               1941


<210>  1143
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  1143
augauaagcg ccucaagagc agcagccgcc agacugguag gagccgcagc aucaaggggc       60

ccgacagcag ccagacacca agacucaugg aacggccuaa gccaugaagc auuccgccuc      120

guaagccgac gcgacuacgc gagcgaagca auaaaaggag ccguggucgg cauagaccua      180

ggaaccacga acucgugcgu ggccguaaug gagggaaaac aagcaaaagu acucgaaaac      240

gccgaagggg caagaacaac gcccucagua guagcguuca cugcggacgg cgaaaggcua      300

guaggcaugc cagcaaaacg acaagcggug acaaacccaa acaacacguu cuacgcaaca      360

aaacgacuca uaggacgacg auacgacgac ccggaaguac aaaaagacau caaaaacguc      420

ccguucaaaa uagugcgcgc caguaacgga gacgccuggg ucgaagccca cggcaaacuc      480

uacagcccau cccagaucgg cgccuucguc cuaaugaaga ugaaagagac cgccgaaaac      540

uaccucggac acacagcuaa aaacgcaguc aucacugugc cagcguauuu caacgacagc      600

caaaggcaag ccacgaaaga cgccgggcaa auaaguggac uaaacguccu aagggucauc      660

aacgaaccga cugcagcggc ccuggcauac ggccuagaca agagcgaaga caaaguaaua      720

gccguauacg accuaggagg cgggacauuc gacauaagca uccuagaaau acagaaagga      780

guauucgagg uaaaaagcac gaauggggac acguuccugg guggcgaaga cuucgaccaa      840

gcacugcuac gccacaucgu gaaggaguuc aaacgagaaa caggggucga ccucacaaaa      900

gacaacaugg cgcuccaacg aguccgcgaa gcagcggaaa aagcaaaaug cgaacuaagc      960

agcagcguac aaaccgacau aaaccuaccc uaccuaacaa uggacaguag cgggccaaaa     1020

caucucaaca ugaaauuaac aagagcucaa uucgaaggca ucguaacgga ccuaauacga     1080

cgaaccaucg ccccgugcca aaaagccaug caagacgcag aaguaagcaa gagcgacaua     1140

ggagaaguaa uacugguagg cggcaugaca agaaugccga aaguacaaca aaccguacaa     1200

gaccuauucg gacgagcacc aagcaaagcc gucaacccgg augaagcagu ggccauuggc     1260

gcagcaaucc agggaggcgu gcuagcgggc gauguaacag acguacuccu acuagacgua     1320

accccgcuaa gccuaggaau agaaacccua ggcggaguau ucacaaagcu gauaaacaga     1380

aacacaacaa ucccaaccaa gaaaagccaa guauucagca ccgcggcaga cgggcaaacc     1440

caaguggaga ucaaagucug ucaaggagaa cgagagaugg ccggcgauaa caaacugcuc     1500

ggccaauuca cccugaucgg cauaccaccc gcgccgagag gaguacccca aaucgagguc     1560

acguucgaua ucgacgccaa cggcauaguc cauguaagcg ccaaagacaa aggaaccgga     1620

cgcgaacaac aaauagucau ccaaucaagc ggaggccuaa gcaaagacga caucgagaac     1680

auggucaaaa acgcggaaaa auacgcagag gaagaccgaa gaaagaaaga aagagucgaa     1740

gcaguaaaca uggccgaagg aauaauacac gacaccgaaa ccaaaaugga agaguucaaa     1800

gaccaacuac cagcugacga augcaacaaa cucaaagaag aaauaaguaa aaugcgagag     1860

cuacuagcgc gcaaagacag cgaaacggga gaaaauauac gccaggcagc gagcagccug     1920

caacaagcua gccuaaaacu guucgaaaug gccuacaaga aaauggcauc cgaaagggaa     1980

ggaagcggaa gcagcggcac cggcgaacag aaagaagacc aaaaagaaga gaaacaguaa     2040


<210>  1144
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  1144
auggcagaua aagaagcagg cggauccgac gggccacgag aaaccgcccc aacauccgca       60

uacagcucgc cagcccgauc acuaggagac accgguauaa cgccccuuuc ccccucccac      120

aucgucaacg acaccgacuc aaacguaucc gaacaacaau ccuucuuagu ugucguggcc      180

gucgacuucg gaacaacauc auccggcuau gccuauucau ucaccaaaga accggagugc      240

auccacguca ugcgucgcug ggaaggagga gaccccgggg uuucaaacca gaaaaccccc      300

accaccaucc uucucacccc cgaacggaaa uuccacuccu ucggcuacgc cgcccgggac      360

uucuaccacg aucuagaccc gaacgaagca aagcaauggc ucuaccuaga aaaauucaaa      420

augaaacuuc acaccaccgg cgaccucaca auggauacag accuuacagc cgcaaacggc      480

aagaaaguca aagcgcucga aaucuucgcc uacgcacucc aauacuucaa agaacaagcc      540

cucaaagagc uauccgacca agccggcuca gaguucgaaa acucagacgu ccgcuggguc      600

auaacaguac cugcgauaug gaaacaaccc gccaaacagu uuaugagaca agcagccuac      660

caggcuggac uggcaucccc ugaaaacuca gaacaacuca uaaucgcgcu agaacccgaa      720

gcugcaagca uauacugccg aaaacuccgc cuccaccaga ugaucgaacu gagcuccaaa      780

gcagccguaa acggauacag cggcuccgac acugucggcg caggauucac ccaagcuaaa      840

gaacacaucc gacgaaaccg ccagucacgc acuuuccuag ucgaaaacgu cauaggagaa      900

aucuggagcg aacuagaaga aggagacaaa uacgucgugg ucgauucagg cggcggcacc      960

gucgaccuaa caguccacca aaucaggcua ccagagggcc accucaaaga gcuauacaaa     1020

gcaaccggcg gccccuacgg aucccucggu guagacuaug aguucgagaa acugcucuac     1080

aaaauauuug gcgaggacuu uaucgagcaa uucaaaauca aacgccccgc cgccuggguc     1140

gacuugauga ucgccuucga aagccgaaaa cgcgccgccg cccccgacag aacaaaccca     1200

cuaaacauca ccuuacccuu cucguucauc gacuacuaca agaaauuucg cggccacucc     1260

gucgagcacg cccuacgaaa aagcaacguc gacuucguca aauggucauc gcaaggaaug     1320

cuccguaugu cccccgacgc caugaaugcc cuauucaaac ccacaauaga cuccaucauc     1380

gaacaccucc gcgaccucuu ucaaaagcca gaaguaucaa ccgucaaauu ucucuuccua     1440

gucggcggcu ucgcagaagc accccuacuc caacaagccg uucaagccgc uuucggcgac     1500

caaugcagaa ucauaauccc acaagacgua ggacucacca uucucaaagg cgccguacuu     1560

uucggccucg acccagccgu cauuaaagug cgaagauccc cucugacaua cggcgucgga     1620

guccuaaacc gcuacgucga aggaaaacac ccacccgaaa aacuucuagu caaagacggc     1680

acccgauggu gcaccgacgu auucgauaaa uucauaucag cagaccaaag cgucgcccuc     1740

ggcgagcuag ucaaaagauc cuacacaccc gccaaaccaa gccaacucgu caucguuauc     1800

aacauauacu ccagcgaaca cgacaacgua ucguucauaa ccgaccccgg gguaaagaaa     1860

ugcggcaccc uccgccucga ccuaacaggc accucaggca ccgccguccc agcacgcaga     1920

gaaauacaaa cccucaugca guucggugac accgaaauca aagccaccgc caucgacaua     1980

gcaaccagua aaucggucaa aguaggcaua gacuuucuaa acuacuaa                  2028


<210>  1145
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  1145
augcuagccg ucccagaaau gggcuuacaa ggacuuuaca ucggaagcuc cccagaacga       60

ucacccguac ccagcccacc cggaucaccc cgcacccagg aaucaugcgg aaucgcgccc      120

cugacaccca gccaaagccc aaaacccgaa guacgggccc cgcaacaagc cuccuucagc      180

guagucgugg ccauagacuu cggaacgacc agcaguggcu acgcauucuc auucgcaagc      240

gauccagagg ccauacacau gaugcgaaaa ugggaaggcg gcgacccagg aguagcacac      300

cagaaaaccc caacaugccu acuccuaacc cccgaaggcg ccuuccacuc auucggcuac      360

acugcaagag auuacuacca cgaccucgac ccggaagaag cccgcgacug gcucuacuuc      420

gagaaauuca agaugaaaau ccacagcgcc acagaccuaa cacugaaaac ccaacucgag      480

gcggugaacg gcaagacaau gccagcacuc gaaguauucg cacacgcccu ccgauucuuc      540

cgcgaacacg cacuacaaga acuacgcgaa caaagcccca gucugcccga gaaggacacc      600

guccgguggg uguuaaccgu acccgcaauc uggaaacaac cagcaaaaca auucaugcgc      660

gaagccgccu acuuagccgg acuuguaagc agagagaacg cagaacaacu ccucauagcc      720

cuggaacccg aagccgccuc cguauacugc cgaaaacuac gacuacacca acuacuagac      780

cugucgggcc gcgcccccgg cggcggccgc cuaggcgaaa gacgaagcau agacuccucc      840

uuccgccaag cccgagaaca acuaagaaga uccagacacu cacgaaccuu ccuaguagaa      900

uccggagucg gagaacuaug ggccgaaaug caagccggcg accgcuacgu agucgccgac      960

ugcggagggg gcacugucga ccuuaccgua caccaacuag aacaaccaca uggcacccua     1020

aaagaacuau acaaagccuc gggagguccc uacggggcug ucggcguaga ccucgcauuc     1080

gagcaacucc uaugccgcau cuucggagaa gacuucaucg caacauucaa acgccaaagg     1140

cccgccgcau gggucgaccu cacuaucgcc uucgaagcac gaaaacgaac agcaggaccc     1200

caucgcgcag gcgcccucaa caucucacua cccuuuuccu ucauagacuu uuacagaaaa     1260

caaagagggc acaacguaga gacagcacuc agacgaucca gcgugaacuu cguaaaaugg     1320

ucaucccaag ggaugcugcg aaugucaugc gaagcaauga acgagcuauu ccaaccaaca     1380

guaucaggca uaauccaaca caucgaagca cugcucgccc gaccagaagu acaaggcgua     1440

aagcuccucu uccuagucgg cggauucgcc gaaagcgcag uccuccaaca ugccguccaa     1500

gccgcccugg gcgcacgcgg acuacgaguc gucguaccac acgacgucgg acucacgaua     1560

cucaaaggag ccguacuauu cggacaagcc ccaggaguag uccgcguccg ccguucgccg     1620

cucaccuacg gcgucggcgu ccucaacaga uucguaccag gacgccaucc cccagaaaaa     1680

cugcuggucc gcgacggccg cagauggugu acagacgucu ucgaacgcuu cguagcagcc     1740

gagcaauccg ucgcgcuagg agaggaaguc cgccguucau acugucccgc cagacccggc     1800

caacgaagag uacucaucaa ccuauacugc ugcgcagcag aagacgcacg cuucauaacu     1860

gacccaggcg uccggaaaug cggcgcccuc ucacuagaac ucgaacccgc cgacugcgga     1920

caggacaccg caggagcccc acccggacga cgcgaaauuc gggccgccau gcaauucggc     1980

gacaccgaaa ucaaggugac agccguggac gucagcacga accgcagcgu uagagcaagc     2040

auagacuucc ucucaaacua a                                               2061


<210>  1146
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  1146
auggcccgcg aaaugaccau ccucggcuca gccguccuua cccuacuacu agcgggauac       60

cuagcccaac aauaccuucc acuacccacc cccaaaguca uagguauaga ccucggaacc      120

accuacugcu ccgucggcgu cuucuuuccc ggaaccggaa aagucaaagu caucccagac      180

gaaaacggac acaucucuau ccccucgaug gucagcuuca cagacaacga cguauacguc      240

ggcuacgaau ccgucgagcu agccgacagc aacccacaaa acacaaucua cgacgccaaa      300

cgcuucaucg gcaaaaucuu caccgccgaa gaacucgaag ccgaaaucgg acgcuacccc      360

uucaaaguac ucaacaaaaa cggcaugguc gaguucucag uaaccagcaa cgaaaccaua      420

accguauccc ccgaauacgu cggcucacgc uuacuacuaa aacucaaaga gauggcagag      480

gcuuaccucg gcaugccggu cgccaacgcu gucauaagcg uccccgcgga guucgaccuc      540

aaacaacgca acuccaccau ugaagcagcg aaccuggcag gacuaaaaau ccuccgggua      600

auaaacgaac ccacagcagc agccauggcc uacggacucc auaaagccga cgucuuucac      660

guucuaguca ucgacuuagg cggaggcacc cucgacgucu cccuccucaa caaacagggc      720

ggaauguucc uaacacgcgc caugucaggc aacaacaaac ucggcggcca ggacuucaac      780

caacgccuac uucaauaccu cuacaaacag aucuaccaga ccuauggauu cguacccucu      840

cggaaagaag aaauccaccg ccuccgccaa gccguagaaa ugguuaaacu caaccucacc      900

cuacaccagu cagcgcaacu auccguccuc cucacggucg aagaacaaga ccgcaaagaa      960

ccccacucau cagacaccga acuccccaaa gacaaacucu ccucagccga cgaccaccgc     1020

gugaacucag gcuucggccg cggccuaucc gacaagaaau ccggcgaauc ucaaguacuc     1080

uucgagacag aaauaagccg caaacucuuc gacacccuaa acgaagaccu cuuccagaaa     1140

auacucguac ccauccaaca aguccuaaaa gaaggccacc uugagaaaac cgaaaucgac     1200

gaagucguuc ucgucggcgg cuccacccgc aucccccgua uucgacaagu cauacaagaa     1260

uuuuucggaa aagaucccaa cacuagcguc gaccccgacc uugcaguagu cacaggggua     1320

gccauccaag ccggaauaga cggcggaucc uggccccuuc aagucuccgc acucgaaauc     1380

cccaacaaac accuucagaa aaccaacuuc aacuag                               1416


<210>  1147
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  1147
auggccgcca ucggagucca ccucggcugc acauccgccu gcguggccgu cuacaaagac       60

ggacgcgcag gcguagucgc caacgacgcc ggagaccgcg ucacccccgc cguagucgcc      120

uacagcgaaa acgaggaaau agucggacuc gccgccaaac aaucccgaau acgcaacaua      180

uccaacacag uaaugaaagu caaacaaauc cucggacgaa gcagcagcga cccacaagcc      240

caaaaauaca ucgccgaauc caaaugccuu gucaucgaga aaaacggaaa acuacgauac      300

gaaaucgaca caggggaaga aaccaaguuc gucaacccag aggacgucgc acgccucauc      360

uucagcaaaa ugaaggagac cgcacauagc guacuagggu ccgacgccaa cgacgucgua      420

auaaccgucc cauuugacuu cggcgaaaaa caaaagaacg cacuaggcga agccgcccgc      480

gccgcuggcu ucaacguccu gcgacuaaua cacgaaccau cagcagcacu acuagccuac      540

ggcaucggac aagacucacc aacaggcaaa ucaaacauac ucguauucaa acucggaggc      600

acuagccuau cacuauccgu aauggaggug aacagcggca ucuaccgcgu acucaguacc      660

aacacagaug acaacauagg cggcgcccac uucacagaaa cccuagcgca auaccuagcg      720

ucggaauuuc aacgcagcuu caaacacgac gucagaggaa acgcccgcgc gaugaugaaa      780

cuaaccaaca gcgcggaagu cgcaaaacac ucccucucaa cccucggcuc cgccaacugc      840

uuccucgacu cacucuacga aggccaggac uucgacugca acgucucaag agcccgcuuc      900

gaacuccugu gcuccccacu auuuaacaaa uguaucgaag caauacgcgg acuccuagac      960

caaaacggcu ucacagccga cgacaucaac aaagucgucc ucugcggcgg cagcucgcgc     1020

auccccaaac uccaacaacu aaucaaagac cucuucccag ccgucgaacu acucaacucg     1080

aucccacccg augaaguuau ucccauugga gccgccaucg aagccggcau ccuaaucggc     1140

aaagaaaacc uacugguaga agacucacua augaucgaau gcucagcccg cgacauccuc     1200

gucaaaggag ucgacgaaag cggagccucc cgauucaccg uacuauuccc uuccggaacg     1260

ccgcucccag cccgccgaca acacacccuc caagcccccg gcuccaucuc cuccgucugc     1320

cucgaacucu acgaaaguga uggcaaaaac ucagccaaag aagaaaccaa auucgcgcaa     1380

guaguacuac aagaccucga caagaaagaa aacggacuac gcgacauccu agccguacuc     1440

accaugaaac gcgacggauc acuccacgua accugcacag accaagaaac aggcaaaugc     1500

gaagcuaucu ccauagaaau cgccucauga                                      1530


<210>  1148
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  1148
auguccgugg uaggacucga cgucgggagc caaagcugcu acauagcggu agccagggca       60

ggcgggauag agacgaucgc caacgaguuc uccgaucgcu gcacacccag cgucaucagc      120

uuugguucua aaaacaggac uauaggagug gccgccaaaa accaacaaau aacccaugca      180

aacaacaccg ucagcaacuu caaacgauuc cacggacgug ccuucaacga ccccuuuaua      240

caaaaagaaa aagaaaaccu auccuacgac cuaguccccc ucaagaaugg aggcgugggc      300

aucaaaguua uguauauggg agaagaacac cuguucucag uagaacagau aaccgccaug      360

cuacuaacaa aacugaagga aaccgcagag aacagucuga agaaaccugu caccgacugc      420

guaaucuccg uacccuccuu cuucaccgac gcagaacgga gauccguacu agacgcagcc      480

caaauaguag gccuaaacug ccuccgccug augaacgaua ugacggccgu agcacucaac      540

uaugggauuu acaaacaaga ccucccaagc cucgacgaaa aaccccgcau aguagucuuc      600

gucgacaugg gacacucagc auuccaggua agcgcaugcg ccuucaacaa aggaaaacuc      660

aaaguccuag gcacggcuuu cgaccccuuc cuaggcggga aaaauuucga cgagaaacuc      720

gucgaacacu ucugcgccga guucaaaacc aaauacaaac ucgacgcaaa gagcaaaauc      780

cgagcccucc uacgccuaua ccaggaaugc gaaaagcuaa agaaacugau guccuccaac      840

uccaccgacc uaccccuaaa caucgaaugu uucaugaacg acaaggacgu cagcggaaag      900

augaacagau cccaguucga ggagcucugc gccgagcuac uccaaaagau agaagucccc      960

cucuacagcc uucucgaaca gacccaccuc aaaguagaag acguuucagc cgucgaaauc     1020

gucggcggag caacacgcau ccccgcgguc aaagaacgca ucgccaaauu cuucgggaag     1080

gacauaucca ccacccuaaa cgcagacgaa gcaguggcac gcgggugugc ccuccagugc     1140

gccauccuaa gccccgcauu caaaguacga gaguucucag uaaccgaugc cgucccguuc     1200

ccaauaagcc ugauauggaa ccacgacagc gaggacaccg aaggugucca cgaagucuuc     1260

agucgaaacc acgcggcccc auucucaaaa guauuaacgu uccuccgacg cggacccuuc     1320

gaacucgaag cauucuacag cgacccgcaa ggcguaccgu acccugaggc aaagauuggc     1380

agguucguag uccagaacgu cuccgcacag aaagauggcg agaaaagccg cguaaagguc     1440

aaaguccgag ucaacacaca cggaaucuuc accauuucca ccgccucaau gguagaaaaa     1500

guccccacag aagaaaacga gaugagcucu gaagccgaca uggagugccu caaccaacgc     1560

ccacccgaaa accccgacac cgacaagaac guccaacaag acaacagcga agcaggaacc     1620

cagccccaag uccaaaccga cgcacaacag accagccaga gcccacccuc ccccgagcuc     1680

acaucagaag aaaauaagau cccagacgca gacaaggcca acgaaaagaa agucgaccag     1740

cccccggagg ccaagaaacc caaaaucaaa guggucaacg uagaacuccc caucgaagca     1800

aaccuggucu ggcagcuagg uaaagacuua cuaaacaugu acaucgaaac cgaaggcaaa     1860

augauaaugc aagauaaacu cgaaaaagaa cgcaacgacg ccaaaaacgc agucgaagaa     1920

uacguauacg aguuccggga caaacuaugc ggcccauacg aaaaauucau cugugaacaa     1980

gaccaccaaa acuuucuacg ucuauuaacc gaaaccgaag acuggcucua cgaagaaggc     2040

gaagaccaag caaaacaggc uuacgucgau aaacuggaag aacuaaugaa aaucggaacg     2100

ccggucaaag ugcgguucca agaagcagaa gaacguccca aaauguucga ggaacucgga     2160

caaagacucc aacacuacgc gaaaaucgcc gccgacuucc gcaacaaaga cgagaaguac     2220

aaccacaucg acgaaucaga aaugaagaaa guagaaaagu cggucaacga aguaauggaa     2280

uggaugaaca acguaaugaa cgcccaagcc aaaaaguccc ucgaccaaga cccagucguc     2340

cgagcacaag aaaucaaaac caaaauuaag gaacugaaca auaccugcga gcccgucgua     2400

acgcaaccga aaccaaaaau agaauccccc aaacucgaac gaacccccaa cgggccgaac     2460

aucgacaaga aagaagaaga ccucgaggac aaaaacaacu ucggagcaga accaccacac     2520

caaaacggcg aaugcuaccc aaacgagaaa aacagcguca acauggaccu cgauuaa        2577


<210>  1149
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  1149
auggcagaca aggucaggcg gcaacgacca cggaggcgcg uauguugggc gcuagucgca       60

guccuacuug cggaccuacu ggcacuaagc gacacgcugg caguuauguc cguagaccuc      120

ggaagcgaau cgaugaaagu cgcgaucguc aaacccggcg ucccaaugga aauaguccua      180

aacaaggaaa gccgcaggaa gaccccggug auagugacac ucaaagagaa cgaacgcuuc      240

uucggagacu cggccgcgag cauggccaua aagaacccca aagcaacgcu aagauacuuc      300

caacaccucc ucgggaaaca agcagacaac ccacacgugg cacucuacca ggcaagguuc      360

ccagaacacg agcugacauu cgacccgcaa cgccaaacgg uacacuucca aauaucauca      420

caacugcaau uuucacccga agaaguccua ggaauggugc ucaacuacuc cagaucauua      480

gccgaagauu ucgccgaaca accaauaaaa gacgcaguca uaacaguacc cgucuucuuc      540

aaccaggcag aacgccgagc aguccuacaa gccgcgagga uggcaggccu uaaaguccuc      600

caacugauca acgacaacac cgcaacagca cugagcuaug gcgucuucag acggaaggac      660

auaaacacca ccgcacagaa uauaauguuu uacgacaugg gaagcggauc cacagugugc      720

accauaguaa ccuaccaaau ggugaaaacg aaggaggccg gcaugcaacc ucagcuccaa      780

auccgagggg uaggauucga ccggacacuc ggcgggcuag aaauggaacu acggcuaaga      840

gaaagauuag cgggacuguu caacgaacag cgaaaaggac aacgagcgaa agacgucagg      900

gaaaaccccc gcgcgauggc aaagcuccuu cgagaggcaa accgccugaa aacagugcug      960

ucagcgaacg cggaccacau ggcucaaaua gaaggacuca uggacgacgu cgacuucaaa     1020

gcaaagguaa cacgagucga auuugaagaa cuaugcgcgg aucuauucga aagagugccc     1080

ggacccguac agcaagcacu gcaguccgcc gaaauguccc uagaugaaau agaacaaguu     1140

auccuagucg gcggcgccac cagaguacca cgagugcagg aaguacuacu caaagccgua     1200

ggcaaggagg aacuagggaa aaacauaaac gccgacgaag cagcagcgau gggggcaguu     1260

uaccaagccg ccgcacucag caaggcauuc aaagucaaac ccuucgucgu acgagacgcc     1320

gucguauacc cgauacuggu agaguucaca cgcgaagugg aggaggaacc aggaauacau     1380

agccugaaac acaacaagcg aguucucuuc agccgaaugg gccccuaccc ccaaagaaaa     1440

gugaucaccu ucaaccggua cagccacgac uucaacuucc acauaaacua cggcgaccuc     1500

ggauucuugg ggcccgaaga ccucagggua uucgggagcc aaaaccugac aacagucaaa     1560

cucaaaggcg uaggcgacag cuucaaaaag uacccagauu acgaaaguaa aggcauaaaa     1620

gcacacuuca aucuugacga aagcggagug cucucgcucg accgcgugga gagcgucuuu     1680

gaaacccuag uagaggacag cgccgaagaa gaaagcacgc uaacaaagcu gggaaacacc     1740

auauccucac uauucggagg gggaacgaca ccagacgcaa aagagaacgg aaccgacacc     1800

guccaagaag aggaagagag cccagcugaa ggguccaaag acgagccagg agaacaaguu     1860

gaacuuaaag aagaagcgga ggccccuguu gaggacggaa gccaaccgcc cccacccgaa     1920

cccaaaggcg acgccacacc agaaggcgaa aaggcaaccg agaaggaaaa cggagacaaa     1980

uccgaagccc aaaaaccaag cgaaaaagca gaggccggcc cagaaggggu cgcgcccgca     2040

ccggaagggg agaagaagca aaaacccgca cgaaaacgca gaauggugga agaaaucgga     2100

guagagcuag ucguacuaga ccuaccagau cugccggaag acaaacuagc acaaucaguu     2160

cagaaacuuc aagacuugac ccuacgggac cuggaaaaac aagaaagaga aaaagcagcc     2220

aacagucucg aagccuucau cuucgagaca caagacaaac uguaccaacc cgaguaccag     2280

gaaguaagca cagaagaaca gagagaagaa aucaguggaa aacugagcgc ugcgucaaca     2340

uggcuagaag acgaaggggu aggugcaaca accgucaugc uuaaagaaaa gcucgccgaa     2400

cugcgcaaac ucugccaagg gcuauucuuc cgaguagaag agaggaagaa auggccagaa     2460

aggcuauccg cacuagacaa ccuacugaac cacucgagca uguuccuaaa gggagcaaga     2520

cucauaccag agauggacca aauauucacc gagguggaaa ugacaacacu cgaaaaggua     2580

auaaacgaaa cgugggccug gaaaaacgcc acacuagcag agcaagccaa acugccagca     2640

acagagaaac caguacugcu aucaaaggac aucgaagcaa aaaugauggc acuggacaga     2700

gaggugcaau accuccucaa caaagcaaaa uucacaaaac ccagaccacg accaaaagau     2760

aagaacggaa cacgcgcaga gccaccccua aaugcuucgg cgagcgauca aggggagaaa     2820

guaauacccc cagccgggca aaccgaggac gccgagccga ucuccgaacc cgaaaagguc     2880

gaaacaggcu cagaacccgg ggauacagaa ccacuugaac ucggcggacc cggagccgag     2940

ccagaacaga aggaacaaag uacagggcaa aaacgccccc ugaaaaacga cgaacuauag     3000


<210>  1150
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  1150
augccagaag aaacccaaac acaagaucaa ccaauggaag aagaagaagu ggaaaccuuc       60

gcguuccagg cggaaauagc ccaacuaaug ucccucauca ucaacaccuu cuacagcaac      120

aaggaaaucu uccugcgaga acuuaucagc aacagcagcg acgcccucga uaagaucaga      180

uacgaaagcc uaacugaccc aagcaaacua gauagcggga aagaacucca caucaaccua      240

auacccaaca aacaagaccg gacccucaca auaguagaca ccggaaucgg aaugacaaag      300

gcggaccuua uaaacaaucu gggaaccauc gcgaaaagcg ggacaaaggc auucauggaa      360

gcgcuccagg caggggcaga cauaucaaug aucggccaau ucggagucgg cuucuacuca      420

gcguaccuag uagccgagaa aguaaccguc auaaccaaac acaacgacga ugagcaguac      480

gcgugggaga gcagcgcggg aggaucguuc acagugagaa ccgacacagg ggaaccgaug      540

ggacgcggaa cgaaaguaau acuacaccuc aaagaagacc agaccgaaua ccucgaagaa      600

aggcgaauaa aagaaauagu gaagaaacac ucccaguuca ucggauaccc gauaacacua      660

uucguggaga aagagcgcga caaagagguc agcgacgacg aagcagaaga aaaagaagac      720

aaagaagagg aaaaggaaaa agaagaaaaa gaaagcgaag acaaaccaga gaucgaagac      780

gugggaagcg acgaagaaga agaaaagaaa gauggagaca agaagaaaaa gaagaaaauc      840

aaagagaaau acauagacca agaagaacua aacaaaacga aaccaaucug gacccggaac      900

ccagacgaca uaaccaauga agaauacggc gaguucuaca aaucacucac aaacgacugg      960

gaagaccacc ucgccguaaa acacuucucg guagagggac aacuagaguu ccgagcgcuc     1020

cuguucgugc caaggcgagc cccauuugac cuguucgaga auagaaagaa gaaaaacaac     1080

auaaaacucu acguccgccg ggucuucauc auggacaacu gugaagaacu aauuccggaa     1140

uaccugaacu ucauccgcgg cguaguggac agcgaagacc ugccgcucaa caucucgaga     1200

gaaauguuac aacaaagcaa aauccucaaa guaauaagga agaaccucgu gaagaaaugc     1260

cuggaauuau ucacagaacu agccgaagac aaagaaaacu acaagaaauu cuacgagcaa     1320

uucagcaaaa acauaaaacu gggcauccac gaagacagcc aaaaccgcaa gaaacuaucc     1380

gagcuccuac gcuacuacac cuccgcaucc ggggaugaga uggugucacu aaaagacuac     1440

ugcaccagaa ugaaagaaaa ccaaaaacac aucuacuaca ucacgggcga aacaaaagac     1500

caaguagcga acucagccuu cgucgagcgc cuacgaaaac acgggcuaga agucauauac     1560

augaucgaac caauagacga auacugcguc caacaacuca aagaguucga aggaaaaacc     1620

cucgucagcg uuaccaaaga aggcuuggag cuccccgaag acgaagaaga gaaaaagaaa     1680

caagaagaaa agaaaaccaa auucgaaaac cugugcaaaa ucaugaagga cauacuggaa     1740

aagaaaguag agaaggucgu aguaucaaac aggcucguga ccagccccug cugcauaguc     1800

acaucuaccu acggauggac ggccaacaug gaaagaauaa ugaaggccca agcacuccgc     1860

gacaacucga caaugggcua cauggcggcc aagaaacacc ucgagaucaa ccccgaccac     1920

uccaucaucg aaacgcucag gcagaaagcc gaagcagaca aaaacgauaa auccgugaag     1980

gaccucguaa uacuccuaua ugaaacggcc cuucuaagca gcggguucag ccucgaagac     2040

ccgcaaacgc acgcgaacag gaucuaccga augaucaaac ucggccuugg gaucgacgaa     2100

gacgacccaa cagcagacga cacgagcgcg gccguaacgg aagaaaugcc accacuagaa     2160

ggcgacgacg acacgagcag gauggaggaa guggacuag                            2199


<210>  1151
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  1151
auggacagcu caaaacugga cucgggcaag ggccugcaca uaaaccuggu cccgaacaag       60

caaaaccaaa cacucacgau cguggacacg cgcauaggca ugaccaagac cgaccucaua      120

aacaaccucg ggaccgugac caagagcggg accaaggccu ucauggaggc ccugcaagcg      180

gacgcggaca uaagcaugau cggacacuuc ggcgugggcu ucuacucggc cuaccucgug      240

gccaagaaag ugaccgugau cucaaaacac aacaacgacg agcaauacac cugggaaucg      300

agcgcgggcg ggagcuucac cgugcgcacg gacgaguaa                             339


<210>  1152
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  1152
augcccgaag aagugcacca cggggaagag gaagucgaaa ccuucgccuu ccaggccgag       60

auagcccaac ucaugagcuu aaucauaaac accuucuacu ccaacaaaga aaucuuccuc      120

agagaguuga uaucaaacgc aagcgacgcc cuggacaaga uaagauacga aagccuaaca      180

gacccaucaa aacuggacuc aggaaaggag uuaaaaauag acaucauccc aaacccacaa      240

gaacgcacgc ucacccucgu ggacaccgga auaggaauga caaaagccga ccucauaaac      300

aaucucggca cgauagccaa gagcgggaca aaagccuuca uggaggcccu acaagcagga      360

gccgacauaa gcaugaucgg acaauucggc guaggcuucu acagcgcaua ccucgucgcc      420

gaaaaggugg uaguaaucac aaaacacaac gacgacgaac aauacgccug ggaaagcagc      480

gccggcggga gcuucacagu cagagcagac cacggcgaac cuauaggacg cgggacuaaa      540

guaauccucc accuaaagga agaccaaacc gaauacuuag aagagcgcag ggucaaggaa      600

gucgucaaaa aacacagcca guucaucggc uaccccauaa cccucuaccu ggaaaaagag      660

agggaaaagg aaauaaguga cgacgaggcc gaggaagaaa aaggagaaaa agaagaagaa      720

gacaaagacg acgaagaaaa gcccaagauc gaagacguag gaagcgacga agaagacgac      780

ucaggaaagg acaagaaaaa aaaaacgaaa aaaaucaaag agaaauacau cgaccaagaa      840

gagcugaaca aaacaaaacc aaucuggacc aggaaccccg augacaucac acaagaagaa      900

uacggggaau ucuacaaauc gcuaacaaac gacugggagg accaccucgc gguaaagcac      960

uucagcgugg aaggacaacu cgaauucaga gcacuacuau ucaucccaag gagagcgcca     1020

uucgaccugu ucgaaaacaa gaaaaaaaaa aacaacauaa agcuauacgu ccgacgaguc     1080

uucauaaugg acucaugcga cgaacugauc ccagaauacc uaaacuucau ccggggcgua     1140

guagacuccg aagaccuccc acucaacauc agccgagaaa ugcuacaaca gagcaagaua     1200

cugaaaguga ucagaaaaaa caucguaaaa aagugccuag aacuauucag cgaauuagca     1260

gaggauaaag aaaacuacaa gaaauucuac gaagccuuca gcaagaaccu aaaacugggc     1320

auacacgaag acagcaccaa ucgaaggcgc cuaagcgaac uacuaagaua ccacacaagu     1380

cagagcggcg acgagaugac gagccuaucc gaauacguua gccggaugaa agaaacgcaa     1440

aagucaauau acuacaucac cggagagagc aaggaacaag uagcgaacuc ggcauucguc     1500

gaacgcgugc gaaagcgcgg auucgaaguc guauacauga cggagcccau cgacgaguac     1560

uguguacaac agcucaaaga auucgacggc aaaagccuag ucucaguaac caaagaagga     1620

cuagaauugc ccgaagacga agaagagaag aaaaaaaugg aagaaucaaa agccaaauuc     1680

gagaacuugu gcaagcugau gaaagagauc cuagacaaaa agguagaaaa ggucacgauc     1740

ucaaaccggc uggugagcuc gcccugcugc aucgucacga gcacauacgg cuggacagca     1800

aacauggaac gaauaaugaa agcacaagcc cucagagaca acucaaccau gggguacaug     1860

auggccaaga aacaccucga aauaaacccc gaccacccua uaguagaaac gcucaggcaa     1920

aaggccgaag cagacaaaaa cgacaaagcc guaaaagacc ucgugguccu gcucuucgaa     1980

acagcccuac ucucaagcgg auuuucacug gaggacccac aaacccacag caacagaauc     2040

uaccgaauga uuaagcucgg acuggguauu gacgaggacg aaguagccgc ggaagagccc     2100

aacgcggcag uccccgacga aaucccgccc cuggaagggg acgaggacgc aucaagaaug     2160

gaagaggucg acuag                                                      2175


<210>  1153
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  1153
augagagccc uaugggugcu cgggcucugc ugcguacuac ucacguucgg aucaguccga       60

gcagacgacg aggucgacgu cgacggaacg gucgaagaag accuaggaaa aagccgcgaa      120

ggcagccgga cagacgacga ggucguccag cgagaggaag aggcaauaca acucgacggu      180

cuaaacgcca gccagauacg cgagcuccgg gagaaaagug aaaaauucgc cuuccaagca      240

gaggucaaca gaaugaugaa acucauaauu aacucccuau acaaaaacaa agaaauauuc      300

cugcgggaac uaaucuccaa cgccagcgac gccuuagaca aaauacgacu caucagccug      360

acagacgaaa acgccuugag cgggaacgag gaacuaaccg ugaaaauaaa augcgacaaa      420

gagaagaacc ugcuacacgu aacggauacg ggaguaggca ugacacgaga agaacucguc      480

aaaaaccucg gaaccauagc caagagcggc acaagcgagu uccucaacaa aaugacagaa      540

gcccaggagg acggccaauc aacgagugag cuuauaggcc aauucggggu aggguucuac      600

agcgcguucc uaguagcgga caaaguaaua gucacaagca aacacaauaa cgauacacag      660

cacauauggg aaucagacag caacgaauuu agcgugaucg cggacccgcg gggaaacacg      720

cuuggcagag gaaccaccau cacucuagua cucaaggaag aggcuucaga cuaucuagaa      780

cuggacacaa ucaaaaaccu cguaaagaaa uacagccaau ucauaaacuu cccgauauac      840

gucuggagcu cgaaaacaga aacaguagag gagccgaugg aggaggaaga ggcagccaaa      900

gaagaaaaag aagaaucgga cgacgaagcg gcagucgaag aagaagagga agagaaaaag      960

cccaaaacca agaaaguaga gaaaaccgua ugggacuggg aacucaugaa cgacauaaaa     1020

cccauauggc agcgcccgag caaagaaguc gaggaagacg aauacaaagc cuucuacaag     1080

agcuucagca aagaaagcga cgacccgaug gccuauauac acuucacagc cgaaggagag     1140

gugacguuca aaagcauccu cuucgucccg acgagcgccc ccaggggacu cuucgacgaa     1200

uacgggagua agaaaagcga cuacaucaaa cuauacgucc gacggguguu cauaaccgac     1260

gacuuccacg acaugaugcc caaguaccug aacuucguca aaggaguggu agauucagau     1320

gaccugccac ucaacguaag cagagagacg cuccaacagc acaaacugcu caagguaaua     1380

cgcaagaagc uagucaggaa aacgcucgac augaucaaaa agauugcgga cgauaaguac     1440

aacgacacgu ucuggaagga guucggaacg aacauaaaac uaggcguaau cgaagaccac     1500

agcaaccgaa caagacucgc aaaacuccuc agauuccaga gcagccauca ccccacagac     1560

auaacaagcc uggaccaaua uguggaacga augaaagaaa aacaggacaa aaucuacuuc     1620

auggcgggau ccagccgcaa agaggcagaa agcagccccu ucguagaacg acuccuaaag     1680

aaaggcuacg aagucaucua cuugaccgaa ccaguagacg aauacugcau ccaggcccuu     1740

cccgaguucg acggcaagag auuccaaaac gucgcgaagg aaggcguaaa auucgacgaa     1800

agcgagaaga cgaaagaauc gagggaagca gucgagaaag aguucgaacc acugcucaac     1860

uggaugaaag acaaagcgcu aaaagacaag auagaaaaag cgguaguauc gcaacggcug     1920

accgaaagcc caugcgcccu agucgcgagc caauacggcu ggagcgggaa cauggaaaga     1980

auuaugaaag cgcaagccua ccagacagga aaggacauca gcaccaacua cuacgccagc     2040

caaaagaaga cguucgaaau caacccaaga cacccgcuaa uaagagacau gcuacgaagg     2100

aucaaggaag acgaggacga caagaccgug cucgaccucg cggucgugcu auucgaaacg     2160

gccacgcuua gaagcggaua ccugcuaccc gacacgaaag ccuacggcga ccgaaucgaa     2220

cgcaugcuaa ggcucagucu aaacauagac cccgacgcga aaguggaaga ggaaccagag     2280

gaggaaccag aagaaacggc agaggacacc accgaggaca cagaacagga cgaggacgag     2340

gagauggacg ucggaacgga cgaagaggaa gaaaccgcaa aggaaucgac cgcagaaaag     2400

gacgagcuau aa                                                         2412


<210>  1154
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  1154
auggcccgcg aauuacgagc ccuacuacua uggggucgcc gacuccgccc acuacuccga       60

gcccccgcac ucgccgcagu cccuggagga aaacccauac ucugcccccg aagaacaaca      120

gcucaacucg gcccccgucg caacccagcc uggucgcucc aggccggccg acucuucucc      180

acacaaaccg ccgaagacaa agaagaaccc cuccacagca uaaucagcag caccgagucc      240

guacaaggaa gcaccuccaa acacgaguuc caggccgaaa ccaagaaacu ucucgacauc      300

guagcccgaa gucuauacuc cgaaaaagaa gucuucaucc gagaacuuau cucuaacgca      360

uccgacgcac ucgaaaaacu acgacacaaa cucguaucag acggucaagc acuacccgaa      420

auggaaauac aucuacaaac caacgcagaa aaagguacca uaacaauuca agacacggga      480

auaggaauga cgcaggagga acucgucuca aaccuaggca cuauagcccg aagcggcagc      540

aaagccuucc ucgacgcccu ccaaaaccaa gccgaagccu ccuccaaaau caucggucag      600

uucggcguag gcuucuauuc cgccuucaug guagcagacc gagucgaagu auauucucgc      660

ucagcagccc ccggcucccu aggcuaccaa uggcuauccg acggcagcgg cguguucgaa      720

auagcagaag ccucgggcgu ccguacaggc accaaaauca ucauacaccu aaaaagcgac      780

ugcaaagaau uuagcucaga agcccgcguc cgagacgucg ucaccaaaua uucaaauuuc      840

gucucauuuc cacucuaucu aaacggcaga cgcaugaaca cgcuccaagc caucuggaug      900

auggacccaa aagacguccg cgaauggcag caugaagagu ucuaccgcua cguagcacaa      960

gcgcacgaca aaccacgcua cacccuccac uacaaaacgg acgccccacu aaacauccgc     1020

uccaucuucu acguaccgga caugaaaccc agcauguucg acguaucccg cgaacucggc     1080

ucaucgguag cacucuacuc uaggaaaguc cucauacaaa caaaagccac cgacauccua     1140

ccaaaauggc uucgauucau cagaggcguc gucgacagug aagacauccc ccucaaccuc     1200

ucacgagaac uccuacaaga auccgccuua auccgaaaac uccgcgacgu acuucaacag     1260

cgucucauaa aauucuucau cgaucaaucc aagaaagaug cagaaaaaua cgccaaauuc     1320

uucgaagacu acggccucuu caugcgggaa ggcaucguaa cagcaaccga gcaagagguc     1380

aaagaggaca uagcaaaacu ccucagauac gaguccagcg cccuucccuc gggccaacua     1440

acuagccuaa gcgaauacgc cucacguaug agagcaggca cccgcaacau cuacuaccuc     1500

ugcgccccaa accgacaccu cgcagaacac ucacccuacu acgaggccau gaaaaagaaa     1560

gacaccgaag uccuguucug cuuugaacaa uucgacgaac ugacccuacu acaccucaga     1620

gaguucgaca aaaagaaacu caucagcguc gagacggaca ucgucguaga ccacuacaaa     1680

gaagaaaaau ucgaggaccg cagcccagcc gcagaaugcc uaucggaaaa agaaaccgaa     1740

gaacucaugg ccuggaugcg gaacguccua ggcuccagag uaaccaacgu aaaagucaca     1800

cucagacuag acacccaccc cgccaugguc accguacuag aaaugggagc ugcccgacac     1860

uuccuacgaa ugcaacaacu agcaaaaaca caggaggaac gcgcccaacu ccuucaacca     1920

acccucgaaa uaaacccccg acacgcccua auaaagaaac uaaaucaacu gagggccucc     1980

gagcccggac ucgcccaacu ucuagucgac cagaucuacg aaaacgccau gaucgcggca     2040

ggccuaguag acgacccccg cgccauggug ggacgacuaa augaacuacu ugucaaagca     2100

cuagagcgac auuaa                                                      2115


<210>  1155
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  1155
augggcaaaa ucuccucccu ccccacccaa cucuucaaau gcugcuucug cgacuuccua       60

aaagucaaaa ugcacaccau guccuccucc caccucuucu accuagcccu cugccuccuu      120

accuucaccu ccuccgccac cgccggcccc gaaacccucu gcggcgccga acucgucgac      180

gcccuccaau uugucugcgg cgaccgcgga uucuacuuca acaaacccac cggcuacggc      240

uccuccuccc gccgcgcacc ccaaaccggc aucgucgacg aaugcugcuu ccgcuccugc      300

gaccuccgcc gccucgaaau guacugcgca ccccucaaac ccgccaaauc cgcccgcucc      360

guccgcgccc aacgccacac cgacaugccc aaaacccaaa aagaagucca ccucaaaaac      420

gccucccgcg gcuccgccgg caacaaaaac uaccgcaugu aa                         462


<210>  1156
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  1156
augggcaucc ccaugggcaa auccaugcuc guccuccuaa ccuuccucgc cuucgccucc       60

ugcugcaucg ccgccuaccg acccuccgaa acacucugcg gcggcgaacu cgucgacacc      120

cuccaauucg ucugcggcga ccgcggcuuc uacuucuccc gccccgccuc ccgcgucuca      180

cgccgcuccc gcggcaucgu cgaagaaugc ugcuuccgcu cuugcgaccu cgcccuccuc      240

gaaaccuacu gcgccacccc cgcaaaaucc gaacgcgacg ucuccacccc ccccacagua      300

cuccccgaca acuucccccg uuaccccguc ggcaaauucu uccaauacga caccuggaaa      360

caauccaccc aacgccuccg ccgcggacua cccgcccuac uccgcgcccg ccgcggccac      420

guccuagcaa aagaacucga agccuuccga gaagccaaac gccaccgccc ccucaucgcc      480

cuccccaccc aagaccccgc ccacggaggc gccccccccg aaauggccuc caaccgcaaa      540

uaa                                                                    543


<210>  1157
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  1157
augaacuccu ucuccaccuc cgccuucggc cccgucgccu ucucccucgg ccuccuacuc       60

guacuccccg ccgccuuccc agcccccguc cccccaggcg aagacuccaa agacgucgcc      120

gccccccacc gccaaccucu caccucaucc gaacgcaucg acaaacaaau acgcuacauc      180

cucgacggca ucuccgcccu ccgcaaagaa accugcaaca aaucaaacau gugcgaaucc      240

ucaaaagaag cccucgccga aaacaaccua aaccucccca aaauggccga aaaagacggc      300

ugcuuccaau ccggcuucaa cgaagaaaca ugccucguca aaauaaucac cggacuccuc      360

gaauucgaag ucuaccucga auaccuacaa aaccgcuucg aaucauccga agaacaagcc      420

cgcgccgucc aaaugucaac caaaguccuc auccaauucc uccaaaaaaa agccaaaaac      480

cucgacgcca ucacaacccc cgaccccacc accaacgccu cccuacucac caaacuccaa      540

gcccaaaacc aauggcucca agacaugacc acccaccuca uccuccgcuc cuucaaagaa      600

uuccuccaau ccucccuccg cgcccuccga caaauguag                             639


<210>  1158
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  1158
augccacucc uguggcuccg cggauuccuc cuagcaagcu gcuggauaau aguacgaagc       60

uccccaacac caggcagcga gggccacagc gccgcacccg acugcccauc cugcgcacuc      120

gccgcccucc caaaagacgu cccgaacagc caacccgaaa uggucgaagc ggucaagaaa      180

cacauacuca acaugcuaca ccuaaagaaa cgcccagacg uaacacagcc aguccccaaa      240

gccgcacuac uaaacgcgau ccgaaaacua cacguaggca aagugggaga aaauggcuac      300

gucgaaaucg aagacgacau aggcagacga gcagaaauga acgaacuaau ggaacaaaca      360

agugaaauaa ucacauucgc cgagagcggc acagcccgga aaacccuaca cuucgaaauc      420

ucaaaagaag gauccgaccu cagcgucgua gaacgagccg aaguguggcu auuccucaaa      480

guccccaaag ccaacagaac cagaaccaaa gucacaauca gacucuucca acagcaaaaa      540

cacccgcaag gaagccucga cacaggcgaa gaagcagagg aagucggacu caaaggugaa      600

cgcagcgaac uccuccuguc cgaaaaaguc gucgacgccc gaaaaagcac auggcacgua      660

uucccaguaa gcagcuccau ccaacgccug cuagaccaag ggaaaucaag ccuggacguc      720

cgcauagcau gcgaacaaug ccaagaaagc ggcgcaagcc uaguacuacu agggaaaaag      780

aaaaagaaag aggaagaagg agaaggaaag aagaaaggag gcggagaagg uggagcaggc      840

gccgacgaag aaaaagaaca aagccaccgg ccauuccuca ugcuacaagc cagacaaagc      900

gaagaccacc cacaccgacg acgccgacga ggccucgaau gcgacggaaa agucaauaua      960

ugcugcaaga aacaauucuu cgucagcuuc aaagacauag gguggaacga cuggaucaua     1020

gccccaagcg gcuaccacgc caacuacugc gaaggagaau gcccaagcca caucgccgga     1080

acauccggga gcagccugag cuuccacagc acgguaauaa accacuaccg caugcgcggc     1140

cacagcccau ucgccaaccu caaaagcugc ugcguaccca ccaaacuacg cccaaugucc     1200

augcucuacu acgacgacgg gcagaacauc auaaagaaag acauacagaa caugaucguc     1260

gaagagugcg gcugcuccua a                                               1281


<210>  1159
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  1159
auggacggcc uaccaggacg agcccucggc gccgcaugcc uccuucuccu cgccgccgga       60

ugguuaggcc ccgaagcaug gggcucaccc accccaccac ccaccccagc cgcaccccca      120

cccccacccc caccaggauc cccaggaggc agccaagaca caugcaccuc gugcggaggc      180

uucagacgcc cugaagaacu aggccgaguc gacggcgacu uccucgaagc cgugaaacgc      240

cauauacucu cccgacucca aaugcgcggc cgacccaaca uaacccacgc cguacccaaa      300

gcagcuaugg uaaccgcccu ccgcaaacuc caugccggca aaguccgaga agacggccga      360

gucgaaaucc cccaccucga cggacacgcc ucccccggcg ccgacggcca agaacgagua      420

ucagaaauca ucuccuucgc ugaaaccgac ggccuggcau ccucccgagu ccgccucuac      480

uucuuuauau ccaacgaagg uaaccaaaac cucuucgucg uccaagccuc acuauggcuc      540

uaccuaaaac uacuccccua cguacucgaa aaaggcagcc gccgcaaagu ccgcguaaaa      600

gucuauuucc aagaacaagg ccacggcgac cgcuggaaca ugguagaaaa acgugucgac      660

cucaaaagau caggcuggca caccuucccc cuaaccgaag cuauccaagc acucuucgaa      720

cgaggagaac gaagacucaa ccucgacgua caaugcgacu cuugccaaga acucgcggua      780

gucccaguau ucgucgaccc cggcgaagaa ucccacagac ccuuuguagu aguacaagcg      840

cgacucggcg acucucgaca ccgaauccgc aaacgcggcc uagaaugcga cggacgcaca      900

aaccucugcu gccgccaaca auucuucaua gacuuccgcc uaaucggcug gaacgacugg      960

aucauagccc ccaccggcua cuacggcaau uacugcgaag gcucaugccc cgcauaccuc     1020

gccggcgucc ccggcucagc auccucuuuc cacaccgccg ucguaaacca auacaggaug     1080

cgcggacuua acccaggaac agucaauucc ugcugcauac ccaccaaacu cagcaccaug     1140

uccaugcucu acuucgacga cgaauacaac aucgucaaac gcgacguccc caacaugauc     1200

gucgaagaau gcggaugcgc auaa                                            1224


<210>  1160
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  1160
auggcccucc guguuuuacu gcucacagca cucacacugu gucacggauu caaccuagac       60

accgaaaaug caaugaccuu ccaagaaaac gcacgcggcu ucggacaauc gguaguccaa      120

cuacaagguu cgcgcguagu cgucggcgcc ccucaagaga uagucgcugc aaaccaacga      180

ggcucacucu accaaugcga cuacucaacc gggucaugcg aaccaaucag acuccaaguc      240

ccagucgaag cagucaacau gagccugggu cucagccucg ccgccacaac cucaccccca      300

caacucuuag caugcggacc aaccguccau cagaccugcu cggaaaacac cuacguaaaa      360

ggccuaugcu uucucuuugg guccaaccua cgacagcagc cccaaaaauu ccccgaagcc      420

cuccgaggau guccgcaaga agacagcgac auagccuuuc ucauugacgg cuccggaucc      480

auaauaccac acgacuuccg ccggaugaag gaauuugucu caacaguuau ggaacaacuc      540

aagaaaucca aaacacucuu cucccugaug caauacagcg aggaguucag aauccacuuc      600

accuucaaag aguuccagaa caaccccaac ccccgcucac ugguaaaacc aauaacucaa      660

cuccucggca ggacacacac ggccacgggc aucaggaagg ucgugcgcga acucuucaac      720

auaacaaaug gugcacgcaa aaacgccuuc aaaauccuug uggucauaac cgacggcgaa      780

aaauucgggg acccauuagg auacgaagac guaauccccg aagcggacag agagggagua      840

auccgauacg ucaucggcgu uggggacgcc uuccguagcg aaaaaucccg ccaggaacuc      900

aacacaauug ccuccaaacc gccccgagac cacgucuucc aagucaacaa cuucgaagcc      960

cucaaaacca uccaaaacca acuccgagag aaaauauucg ccauagaagg aacccaaacc     1020

ggcagcucca gcuccuucga acaugaaaug ucccaagaag gcuucagcgc cgcgaucacc     1080

uccaacggcc cucuacucuc uaccgucgga ucauacgacu gggcuggcgg cgucuuccuu     1140

uacaccucca aggaaaaauc gacauucauc aacaugacca gagucgauuc ugacaugaac     1200

gacgcauauc ucggcuacgc cgcugcuauc auucuacgca acagagugca aucucuagua     1260

uuaggagccc cucguuacca acacaucggc cuaguggcaa uguuccguca aaacaccggg     1320

augugggaaa gcaacgcgaa cgucaagggc acccaaaucg gcgcauacuu cggagcuucu     1380

cucugcucug uggacgucga cucaaacgga agcacugauc ucguucuuau cggagcaccc     1440

cacuacuaug agcagacucg aggaggccaa guaucagucu guccacuccc ccguggccga     1500

gcccgcuggc aaugcgacgc gguucuauau ggcgaacaag gucaacccug gggcagguuc     1560

ggugccgcgc ucaccguccu uggagacguc aacggcgaca aacucaccga cguagcaauc     1620

ggcgcaccug gcgaggaaga caaccgcggc gcaguguacc ucuuccacgg caccuccggc     1680

agcggcaucu cacccuccca cucacaacgc auagccggcu cuaaacuguc ccccagacug     1740

caauacuucg ggcaaagccu auccggugga caagaccuca cgauggacgg ccuaguagau     1800

cugacgguug gcgcgcaagg gcauguacuu cuacuacgau cccaaccagu acuacguguc     1860

aaggcaauca uggaguucaa uccacgggaa gucgcacgaa acgucuucga augcaacgac     1920

caaguuguca agggcaaaga agccggcgaa gucagagugu gucugcacgu acaaaagagc     1980

acacgugauc gacugcgaga aggacaaauc caguccgugg ucaccuacga ccuagcccua     2040

gacuccggaa gaccccacag ccgugccguc uucaacgaaa ccaaaaauuc aacccgccgg     2100

caaacccagg ugcuaggccu uacccaaacu ugcgagacgc ucaaacuaca acugcccaac     2160

uguaucgaag acccagucuc accaaucgua cuacgccuua auuuuucccu agucggcaca     2220

ccccucucag cauucggaaa ccuccgaccc guccucgccg aagacgccca acgacuuuuc     2280

accgcccuau uccccuucga aaagaacugc ggcaacgaca acauauguca agacgaccuc     2340

agcaucaccu ucucuuucau gucgcucgac ugccuagugg uaggcggacc ccgagaauuu     2400

aacgucacag ucaccguaag aaacgacgga gaggauuccu acagaacgca aguuacauuc     2460

uucuucccgc ucgaccucuc guaccgcaaa gucucgaccc uucaaaacca acgaucucaa     2520

cgaucuugga ggcucgcaug ugaaucagcc ucgucaacag aaguaagugg cgcccucaaa     2580

ucgaccuccu guuccauaaa ccacccaauc uuccccgaga acagcgaagu cacauucaac     2640

auaacauucg acguugacuc uaaagcauca cucggcaaca aacucuuacu gaaagccaac     2700

gucaccagcg aaaacaacau gccaagaaca aacaaaacag aguuccaacu cgaacuccca     2760

gucaaguaug ccguauacau ggucgucacc agccacggag uauccacaaa auaccucaac     2820

uuuaccgcca gcgaaaacac guccagagua augcaacacc aauaccaggu auccaaccuu     2880

ggucaacgca gucuacccau cucccuagug uuccucguuc ccgucagacu aaaccagaca     2940

guaauauggg accguccaca aguaacauuc ucugaaaacc ucuccuccac augucacacu     3000

aaagaacgac ucccuagcca uuccgacuuu cuugcagagc uucgcaaagc cccuguugug     3060

aacugcucaa ucgcgguaug ccagcgcaua cagugcgaca uaccauucuu ugggauacag     3120

gaagaguuca acgcgacucu caaagguaac cucagcuucg acugguauau caagaccuca     3180

cauaaccacc uccuaauagu auccacagcc gaaauccucu ucaacgacag cgucuucaca     3240

uugcugcccg gccaaggagc uuucguacga ucgcagacag aaacuaaagu agaaccuuuc     3300

gaagucccga acccgcuccc gcuaaucguc ggauccuccg uuggcgggcu acuccuucuu     3360

gcccucauca cagcagcacu guauaagcuc ggcuucuuca agcgccaaua caaagauaug     3420

auguccgaag gcggcccgcc cggggccgaa ccccaguaa                            3459


<210>  1161
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  1161
auguucuccc ucaaaaccuu accguuccuc cuacuacuac acguccaaau cuccaaagcc       60

uucccugucu ccagcaaaga gaaaaacacu aaaaccguac aggacuaccu cgaaaaauuc      120

uaccaacuac ccucaaacca guaccagucc acccgcaaaa acggcacaaa cgugaucguc      180

gaaaagcuaa aagaaaugca acgcuucuuc ggccuaaacg ucacaggcaa acccaacgaa      240

gaaacccucg acaugaugaa gaaaccccga ugcggcgucc ccgacuccgg cggcuucaug      300

cucacacccg guaaccccaa augggaacga accaaccuaa ccuaccgcau acgaaacuac      360

acaccccaac ucucagaagc cgaagucgaa cgagcuauca aagacgcauu ugaacucugg      420

uccgucgcau caccccucau cuucacccgc aucucucaag gcgaagccga cauaaauauc      480

gccuucuauc aaagagacca cggcgacaac ucccccuucg acggcccgaa cgguauccuc      540

gcacacgccu uccaaccagg ccaaggaauc ggcggcgaug cccacuucga cgcagaagaa      600

accuggacaa acaccucagc caacuacaac cucuuccucg ucgccgcgca cgaguucgga      660

cauucccucg gccuagccca cuccuccgac cccggugcac ucauguaccc aaacuacgcc      720

uuccgcgaaa ccagcaacua cucacucccc caagacgaca uagacggcau ccaagccaua      780

uacggacuau cauccaaccc cauccagcca accggacccu caacccccaa acccugcgau      840

ccaucccuca ccuucgacgc caucaccacc cuacguggag agauccucuu cuucaaagau      900

cgauauuucu ggcgccgaca cccccaacug caacggguug aaaugaacuu caucagccuc      960

uucuggccuu cacuacccac cggaauccaa gccgccuaug aagacuuuga ccgcgaccuc     1020

aucuuccucu ucaaaggaaa ccaauacugg gcccucucgg guuacgacau ccuucaaggc     1080

uacccuaaag acauaucaaa cuacggauuc ccaucguccg uccaagccau cgaugccgca     1140

guuuucuacc gcuccaaaac cuacuucuuc gucaacgacc aauucuggcg cuaugacaac     1200

caacgccaau ucauggaacc aggauacccc aaauccaucu ccggcgccuu ccccggcauc     1260

gaaagcaaag ucgacgcagu cuuccaacaa gaacacuucu uccacguuuu cucaggcccu     1320

cgcuacuacg ccuucgaccu aaucgcccaa cgagucaccc gagucgcccg aggaaacaaa     1380

uggcuuaacu gccgcuacgg auag                                            1404


<210>  1162
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  1162
augucccucu ggcaaccucu cguauuagua cuccuagucc uuggaugcug cuuugccgcu       60

ccucgacaac gccaauccac acucguccuu uucccagggg aucuaagaac caaccuuacc      120

gaccggcaac uagcagagga auaccuauac cgcuauggau acacaagagu cgccgaaaug      180

agaggagaau cgaaaagccu cggaccagcc cuccuacuac uacaaaaaca acucucccug      240

cccgaaacug gcgaacucga cucugccacu cuaaaagcaa ugaggacccc acgaugcggc      300

guccccgacc uaggcagauu ccaaaccuuc gaaggcgauc uaaaauggca ccaccacaac      360

auaaccuacu ggauccaaaa cuacucagaa gaccuccccc gagccguaau agacgaugcc      420

uucgcaagag cuuucgcccu cuggucggca gucacucccc ucaccuuuac cagaguauac      480

ucccgagacg ccgacauagu cauccaauuc ggcgucgccg aacacggcga cggcuacccc      540

uucgacggaa aagauggacu ccucgcucac gcguucccac caggcccagg uauccaaggc      600

gaugcucacu ucgacgacga cgaacuaugg ucucucggaa aaggggucgu cguccccacc      660

cgauucggaa acgcagacgg cgccgcuugc cacuuccccu ucaucuucga aggacguucc      720

uacagcgccu gcacgaccga cggaagaucc gauggacuac cauggugcuc aacgaccgcc      780

aacuacgaca cagacgacag auucggauuc ugucccucag aacgucucua cacacaagac      840

ggcaacgccg auggcaaacc cugccaauuc cccuucauau uccaaggcca auccuacucc      900

gccugcacaa ccgacggacg cucugacggc uaccgauggu gcgcuacaac agcaaacuau      960

gaucgagaca aguuauuugg auucugcccc acccgcgccg auuccaccgu aauggguggg     1020

aacuccgcag gagaacucug cgucuucccc uucaccuucc ucggaaaaga guacagcaca     1080

ugcaccuccg aaggccgagg cgacggccgc cuauggugcg ccaccaccuc caacuuugac     1140

ucagacaaga aaugggguuu cugccccgac caagguuaca gccucuuccu cgucgccgca     1200

caugaauuug gacacgcauu aggccuagac cacucgucag uccccgaagc ccucauguac     1260

cccauguaca gauucacuga aggcccaccc cuccacaaag acgacgucaa cggaauccgc     1320

caucucuacg gcccccgacc agaaccugaa ccacgcccac ccacaaccac cacaccccaa     1380

cccaccgccc cacccacugu cugccccacc ggcccaccca ccguccaucc cagcgagaga     1440

cccaccgcgg gcccaaccgg cccacccucc gcaggcccca cuggaccccc aaccgcagga     1500

cccuccaccg cuacuaccgu uccacuaucc ccagucgacg acgcuugcaa cgucaacauc     1560

uucgacgcca uagcugagau aggaaaccag cucuaccuau ucaaagacgg aaaauacugg     1620

cgauucuccg agggacgcgg cucccgcccc caaggaccau uucuaauagc agacaagugg     1680

cccgcacucc cacgcaaacu ugacuccguu uucgaggaaa gacucuccaa gaaacuauuc     1740

uucuuuuccg gccgacaagu cuggguuuac acaggcgccu ccguacucgg uccucgccgc     1800

cuugacaaac uagggcucgg cgcagacguc gcccagguaa caggagcucu ccgaagcgga     1860

aggggcaaaa uguuacucuu cuccggccgu cgacucuggc gauucgacgu aaaagcccaa     1920

augguagauc ccagaagcgc cagcgaaguc gaccgcaugu ucccaggagu cccccuugau     1980

acccacgacg ucuuccaaua ccgcgaaaaa gccuacuuuu gccaagaccg cuucuacugg     2040

cgcgucucua gcagaucaga acuuaaccaa guagaccaag uaggcuacgu caccuacgac     2100

auccuacagu gcccagaaga cuaa                                            2124


<210>  1163
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  1163
augcaccccg gcguacucgc agccuuccua uuccuauccu ggacccacug ccgcgcauua       60

ccccuccccu caggaggcga ugaagacgac cuuuccgaag aagaccugca auucgccgaa      120

cgcuaccucc gauccuacua ccaccccacc aaccucgccg gcauacucaa agaaaacgca      180

gccucaucca ugacagaacg ccuccgcgaa augcaauccu ucuuuggccu cgaagucacc      240

ggaaaacuug acgacaacac gcuagacguc augaaaaaac ccagaugcgg aguccccgac      300

gucggcgaau acaacgucuu ccccagaacc cuaaaauggu caaaaaugaa ccucaccuac      360

agaauaguca acuacacccc ugacaugacc cacuccgaag uagaaaaagc cuucaaaaaa      420

gccuucaaag ucuggucuga cguuaccccc cucaacuuca cccgacucca cgacggcauc      480

gccgacauaa ugaucuccuu cggaaucaaa gaacacggcg acuucuaccc cuucgacgga      540

ccaucaggcc uacucgccca cgccuuccca ccaggaccca acuacggagg cgacgcccac      600

uucgaugacg acgaaaccug gaccuccucc uccaaaggcu acaaccucuu ccuaguagcc      660

gcacacgaau ucggccacuc acuaggacua gaccacucca aagaccccgg cgcucuuaug      720

uuccccaucu acaccuacac ugggaaaucc cacuucaugc uccccgacga cgacguacaa      780

ggcauccaaa gccucuacgg cccgggcgac gaagauccca accccaaaca ccccaaaaca      840

ccagacaaau gcgaccccuc acuaucacua gacgcaauca ccucccuccg uggcgaaacu      900

augaucuuca aagaccgauu cuucuggcgc uuacaccccc aacaagucga cgccgaacuc      960

uuccuuacca aaucauucug gcccgaacuc cccaaccgca ucgacgccgc cuacgaacac     1020

cccagccaug accucaucuu uaucuuccgc gggagaaaau ucugggcacu aaacggauac     1080

gacauacucg aaggcuaccc aaaaaaaauc uccgaacuag gccucccaaa ggaagucaaa     1140

aagaucuccg cagcaguaca cuucgaagac accggcaaaa cccuccuauu cucagguaac     1200

caaguauggc gcuacgacga caccaaccac aucauggaca aagacuaccc ccgccucauc     1260

gaagaagacu uccccggcau aggcgacaaa gucgacgccg ucuaugaaaa aaacggcuac     1320

auauacuucu uuaacggccc cauccaauuu gaauacucca uaugguccaa ccgcaucgua     1380

cgcguuaugc cagccaacuc cauccucugg ugcuaa                               1416


<210>  1164
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  1164
auggaaaccc cgaacaccac cgaagauuac gacaccacaa ccgaguucga cuacggcgac       60

gccacccccu gccaaaaagu caacgaacgc gccuucggcg cccaacuccu cccaccccuu      120

uacucccucg ucuucgucau cggccucguc ggcaauaucc ucguaguccu cguccucguc      180

caauacaaac gacucaaaaa caugaccucc aucuaccuac ucaaccuugc caucuccgac      240

cuccucuucc ucuucacccu ccccuucugg auagacuaca aacucaaaga cgacuggguc      300

uucggcgacg ccaugugcaa aauccucucg ggcuucuacu acacaggacu cuacuccgaa      360

aucuucuuca ucauccuccu aacuaucgac cgcuaccuag ccaucgucca cgccgucuuc      420

gcacuacgcg cccgcaccgu aaccuucggc gucaucaccu caaucaucau cugggcccuc      480

gccauccucg ccuccaugcc cggccucuac uucucaaaaa cccaauggga guucacacac      540

cacacaugcu cacuccacuu cccccacgaa ucccuacgcg aauggaaacu cuuccaagcc      600

cucaaacuca accuauucgg ccuaguccuc ccacuacucg ucaugaucau cugcuacaca      660

ggcaucauca aaauacuccu ccgccgcccc aacgaaaaga aauccaaagc aguccgccuc      720

aucuuuguca uaaugauaau cuucuuccua uucuggaccc ccuacaaccu caccauccuc      780

aucucaguau uccaagacuu ccucuucacc caugaaugcg aacaaucacg ccacuuagac      840

cucgccgucc aagucaccga ggucauugcc uacacccacu gcugcgucaa cccaguaauc      900

uacgccuucg ucggcgaacg cuuccgcaaa uaccuccguc aacuauucca ccgacgcguc      960

gccguacacc ucgucaaaug gcuccccuuc cuaucugucg accgacuaga acgcgucucc     1020

uccacaagcc caagcaccgg cgaacacgaa cucuccgccg gcuucuag                  1068


<210>  1165
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  1165
augcgcacac ucgccugccu ccuacuccuc ggcugcggcu accucgcaca cguccucgcc       60

gaagaagccg aaaucccccg agaagucauc gaacgacucg cccgcuccca aauccacucc      120

auccgcgacc uccaacgccu ccucgaaauc gacuccgucg gcuccgaaga cucccucgac      180

accucacucc gcgcccacgg aguccacgcc accaaacacg uacccgaaaa acgaccccuc      240

cccauccgcc gaaaacgcuc cauagaagaa gccguccccg ccgucugcaa aacccgcacc      300

gucaucuacg aaaucccccg cucccaaguc gaccccacau ccgccaacuu ccucaucugg      360

ccccccugcg uagaagucaa acgcugcacc ggcugcugca acacauccuc cguaaaaugc      420

caacccuccc gcguacacca ccgcuccguc aaagucgcca aagucgaaua cguccgcaaa      480

aaacccaaac uaaaagaagu ccagguccgc cucgaagaac accucgaaug cgccugcgcc      540

accaccuccc ucaacccaga cuaccgcgaa gaagacaccg gccgcccccg cgaauccggc      600

aaaaaacgca aacgcaaacg ccugaaaccc accuaa                                636


<210>  1166
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  1166
augaaccgau gcugggcccu cuuccucagc cucugcugcu accuacgacu uguaucagcc       60

gaaggcgacc caaucccaga agaacuauac gaaaugcugu ccgaccacuc cauccgcucc      120

uucgacgacc uccaacgccu ccuccacggu gaccccggcg aagaagacgg cgccgaacua      180

gaccuuaaua ugacccgcuc ccacuccggc ggagaacucg aaucacucgc ccgcggacgc      240

cgcucccuag gcucccucac caucgccgaa ccagccauga ucgccgaaug caaaacacgc      300

accgaaguau ucgaaaucuc acgccgacuc aucgaccgca ccaacgccaa cuuccuuguc      360

uggcccccau gcgucgaagu ccaacgcugc uccggcugcu gcaacaaccg caacguacaa      420

ugccgaccca cacaaguaca acuccgccca guccaaguac gcaaaaucga aaucguccgc      480

aaaaaaccaa ucuucaaaaa agccacaguc acccucgaag accaccucgc cugcaaaugc      540

gaaaccguag ccgccgcacg ccccgucacc cgcucacccg gcggaucaca agaacaacgu      600

gcaaaaaccc cccaaacccg cgucacaauc cgcaccgucc gcguccgccg cccccccaaa      660

ggaaaacacc gcaaauucaa acacacacac gacaaaaccg cccucaaaga aacccuaggc      720

gccuaa                                                                 726


<210>  1167
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  1167
augagccucu ucggccuccu ccuccucacc uccgcccugg ccggccagcg ccaaggcacc       60

caggccgaau ccaaccucuc cuccaaauuc caauucuccu ccaacaaaga acaaaacggc      120

guccaagacc cccaacacga acgaaucauc accgucucaa caaacggcuc aauacacuca      180

ccacgcuucc cccacaccua cccaagaaac accguccucg ucuggcgccu agucgccguc      240

gaagaaaacg uauggaucca acucaccuuc gacgaacgcu ucggccucga agacccagaa      300

gacgacaucu gcaaauacga cuucguagaa gucgaagaac cuagcgacgg caccauacuc      360

ggacguuggu gcggcuccgg caccgucccc ggcaaacaaa ucuccaaagg caaccaaauc      420

cgaauacgcu ucguauccga cgaauacuuc ccauccgaac ccggcuucug cauccacuac      480

aacaucguca ugccccaauu caccgaagcc gucucccccu ccguacuacc ccccuccgcc      540

cucccccucg aucuucucaa caacgccauc acggccuucu ccacccucga agaccuaaua      600

cgcuaccugg aacccgaaag auggcaacuc gaucucgaag aucuauaccg ccccacaugg      660

caacuccucg gcaaagccuu cgucuucggc agaaaauccc gggucguaga ccucaaccuc      720

cucaccgaag aaguacgccu auacuccugc acaccacgca acuucuccgu auccauccga      780

gaagaacuca aacgcaccga cacuaucuuc uggcccggcu gccuccucgu caaaagaugc      840

ggcggaaacu gcgccugcug ucuccacaac ugcaacgaau gccaaugcgu ccccuccaaa      900

guaaccaaaa aauaccacga aguccuacaa cuucgcccaa aaaccggcgu aagaggccuc      960

cacaaauccc ucaccgacgu cgcacuagaa caccacgaag aaugcgacug cgucugccgc     1020

ggcuccaccg gaggauaa                                                   1038


<210>  1168
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  1168
augcaccgcc uaaucuucgu cuacacccua aucugcgcca acuucugcuc cugccgagac       60

accuccgcca ccccacaauc cgccuccaua aaagcacucc ggaaugccaa cuuacgccgg      120

gacgaccuau accgucgaga cgaaacaauc caaguaaaag gaaacggcua cgugcaaucg      180

ccccgauucc caaacuccua cccacgcaac cuccuccuca ccuggcgacu acacucccaa      240

gaaaacacuc gcauccaacu cgucuucgac aaccaguucg gccuggaaga agccgaaaac      300

gacaucugcc gcuacgacuu cgucgaaguc gaagacauau cagaaaccuc caccaucaua      360

cgcggccgcu ggugcggcca caaagaggua cccccccgca ucaaaucccg cacaaaccaa      420

aucaaaauaa ccuucaaauc agacgacuac uucguagcua aacccggauu caaaaucuac      480

uacucccucc uagaagacuu ccaacccgcc gcagcauccg agaccaacug ggaauccgua      540

accuccucca uauccggcgu auccuacaac agccccuccg ucacagaccc cacccuuaua      600

gccgacgccc ucgacaaaaa aaucgccgaa uucgacaccg ucgaagaucu ccuaaaauac      660

uucaaccccg aaucauggca agaagaccuc gaaaacaugu accuagacac cccacgauac      720

cgcggacgcu cauaccacga ccgaaaaucc aaagucgacc ucgaccgacu caacgacgac      780

gccaaacgcu acagcugcac accacgcaac uacuccguca acauccgcga agagcuaaaa      840

cucgccaacg uagucuucuu cccccgcugc cuucucgucc aaagaugcgg cggcaacugc      900

ggcuguggaa ccguaaacug gcgcagcugc accugcaacu caggcaaaac cgucaaaaaa      960

uaccacgaag uccuccaauu cgaaccaggc cacaucaaac gccgcggccg agccaaaaca     1020

auggcccucg ucgacaucca gcucgaccac cacgaacgcu gcgacugcau augcuccagc     1080

cgccccccuc gcuaa                                                      1095


<210>  1169
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  1169
auggucaccc acuccaaauu cccugccgca ggcauguccc gaccccucga caccucccuc       60

cgacucaaaa ccuucuccuc aaaguccgaa uaccaacucg ucgucaacgc cguccguaaa      120

cuccaagaau ccggcuucua cugguccgcc gucaccggug gugaagcaaa ccuccuccuc      180

uccgcagaac ccgccggcac cuuccucauc cgcgacuccu cagaccaacg ccacuucuuc      240

acccucucag ucaaaaccca auccggcacc aaaaaccucc gcauccaaug cgaaggcggc      300

uccuucuccc uccaauccga cccacgcucc acacaaccug ucccacgcuu cgacugcguc      360

cucaaacucg uccaccacua caugccaccc cccggcgccc ccuccuuccc aucccccccc      420

accgaacccu ccucagaagu ccccgaacaa cccucagccc aaccccuccc cggcuccccc      480

ccccgccgcg cauacuacau cuacuccggc ggcgaaaaaa ucccacucgu acucucccgc      540

ccccucuccu ccaacgucgc cacccuacaa caccucugcc gcaaaaccgu caacggccac      600

cucgacuccu acgaaaaagu cacccaacua cccggcccca uccgcgaauu ccucgaccaa      660

uacgaugcac cccuauaa                                                    678


<210>  1170
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  1170
augguccccu ccgccggcca acucgcccua uucgcccucg gaaucguccu cgcagccugc       60

caagcccucg aaaacuccac cuccccccuc uccgccgacc cccccgucgc cgccgccguc      120

gucucccacu ucaacgacug ccccgacucc cacacccaau ucugcuucca cggcaccugc      180

cgcuuccucg uccaagaaga caaacccgcc ugcgucugcc acuccggcua cgucggcgcc      240

cgcugcgaac acgccgaccu ccucgccguc gucgccgccu cccaaaaaaa acaagccauc      300

accgcccucg ucgucgucuc caucgucgcc cucgccgucc ucaucaucac cugcguccua      360

auccacugcu gccaaguccg caaacacugc gaauggugcc gcgcccucau cugccgccac      420

gaaaaacccu ccgcccuccu caaaggccgc accgccugcu gccacuccga aacagucguu      480

uaa                                                                    483


<210>  1171
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  1171
augccucccu cuggccuucg acugcucccc cuccuccucc cccuccuaug gcuccuaguc       60

cuaacacccg gccgcccagc cgcaggccuc uccacaugca aaacaauaga cauggaacuc      120

gucaaacgaa aacgcaucga agcaauccgc ggccaaauac ucucuaaacu ucgccucgcc      180

ucaccacccu cccaaggcga agucccacca ggaccccucc ccgaagccgu auuagcucuc      240

uacaacucca cacgcgaccg cgucgcaggc gagagcgccg aacccgaacc cgaaccugaa      300

gcugacuacu acgccaaaga aguaacacgc guccucaugg uugaaaccca caacgaaauc      360

uaugacaaau ucaaacaauc cacccacuca aucuacaugu ucuuuaacac aucagaacuc      420

cgcgaagccg uccccgaacc aguccuccuu ucccgugccg aacuccgccu acugcgccuc      480

aaacuaaaag uagaacaaca cguugaacuc uaccaaaaau acucaaacaa uuccuggcga      540

uaccucucca accgccuccu cgcccccucc gacagccccg aauggcucuc uuuugacguc      600

acaggcgucg uacgccaaug gcucucaaga ggcggcgaaa ucgaaggcuu ccgccucuca      660

gcccauugcu cuugcgacuc ucgcgacaac acccuccaag ucgacaucaa cggcuucacc      720

accggccgac gcggcgaccu cgccaccauc cacggcauga accguccuuu ccuacuucua      780

auggccacac cccucgaacg cgcccaacac cuccaaucau cacgccacag acgcgcccuc      840

gacaccaacu acugcuucuc cuccaccgaa aagaacugcu gcguacgcca acucuacauc      900

gacuuccgua aagaccucgg cuggaaaugg auccacgaac ccaaaggcua ccacgccaac      960

uucugucuug gcccaugccc cuacaucugg ucccuagaca cucaauacuc caaaguccua     1020

gcccuuuaca accaacacaa ccccggcgca ucagccgccc ccugcugcgu accccaagcc     1080

cucgaaccac uccccauagu cuacuacgua ggccgaaaac ccaaagucga gcaacuaucc     1140

aacaugaucg uccggucgug caaaugcucc uaa                                  1173


<210>  1172
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  1172
augcacuacu gcguccucuc cgccuuccuc auauuacacc ucgucaccgu ugcccuaucc       60

cucucgacuu gcuccacccu cgacauggac caauucaugc gcaaaagaau cgaagcaauc      120

cgaggccaaa uccucucaaa acucaaacuu acaucccccc cugaagacua uccagaaccc      180

gaggaagucc ccccugaagu cauauccaua uacaacagca cccgcgaccu acuccaagaa      240

aaagccucgc gacgagccgc agccugcgaa cgcgaacgca gcgacgaaga auacuacgcc      300

aaggaagucu acaaaaucga caugccgccc uucuucccau cagagaaugc uauccccccc      360

accuucuacc gaccauacuu ccgcaucguc cgcuucgacg ucuccgcaau ggaaaaaaac      420

gccuccaacc ucgucaaagc cgaauuccgc gucuuccgcc ugcaaaaccc caaagcccgc      480

guucccgaac aacgcaucga acucuaccaa auacucaaau ccaaagaccu caccucuccc      540

acccaacguu acaucgacuc uaaaguaguc aaaacacgcg ccgaaggcga auggcucucc      600

uucgacguaa ccgacgccgu acacgaaugg cuccaccaca aagacagaaa ccucggauuc      660

aaaaucuccc uacacugccc cugcugcacu uucguccccu ccaacaacua cauaauuccc      720

aacaaauccg aagagcuuga agcccgcuuc gccggcaucg acggaaccuc gaccuacacu      780

ucaggcgacc agaaaaccau uaaauccacc cgcaaaaaaa acucgggcaa aacaccccac      840

cuccuacuca ugcuccuccc auccuaccgg cuagaauccc aacaaaccaa ccgacgcaaa      900

aaacgagccc ucgacgcagc cuacugcuuc cguaacgucc aagacaauug cugccuacgc      960

ccacucuaca ucgauuucaa acgugaccuc ggauggaaau ggauccauga acccaaaggc     1020

uacaacgcca acuucugcgc aggcgcaugc cccuaccucu ggagcuccga cacccaacac     1080

ucccgcgucc uaagccuuua caacaccauc aaccccgaag ccucagccuc ccccugcugc     1140

gucucccaag accucgaacc acuaacaauc cucuacuaca ucggcaaaac ccccaaaaua     1200

gaacaacucu ccaacaugau cgucaaaucc ugcaaaugcu ccuaa                     1245


<210>  1173
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  1173
augaaaaugc accuccaacg agcccuaguc guccucgcac uacucaacuu cgcaaccguc       60

ucccuaagcc uuuccacaug caccacccug gacuucggcc acaucaaaaa gaaacguguc      120

gaagccauuc gaggccaaau acucagcaaa cuccgccuca caucaccccc agaacccaca      180

guuaugaccc acguccccua ccagguccua gcccuauaca acagcacccg cgaacuccuc      240

gaagaaaugc acggcgaacg cgaagaaggc ugcacccaag aaaauacaga guccgaauau      300

uaugcaaaag aaauccacaa auucgacaug auccagggcc ucgccgaaca caacgagcuc      360

gccgucuguc ccaaaggcau caccuccaaa guauucagau ucaacguguc auccgucgag      420

aaaaaccgca ccaaccucuu ccgcgccgag uuccgugucc uccgcguccc aaaccccucc      480

agcaaacgaa acgaacaacg aauagaacua uuccagaucc uccgccccga cgaacacauc      540

gccaaacaac gcuacauugg gggcaaaaac cuccccaccc gcggaacagc cgaauggcua      600

uccuucgacg ucaccgacac cguccgcgaa uggcuacuaa gaagagaauc caaccucggc      660

cucgaaaucu ccauacacug ccccugccac accuuccaac ccaacggaga cauacucgaa      720

aacauccacg aaguaaugga aaucaaguuc aaaggagucg acaacgaaga cgaccacggc      780

cgcggcgacc uaggccgccu caaaaagcag aaagaccacc acaaccccca ccuaauacua      840

augaugauac ccccucaccg ccucgacaac cccggccaag gcggacaacg caaaaagcgc      900

gcccucgaca cuaacuacug cuuccgcaac cucgaagaaa acugcugcgu ccgcccccuc      960

uacaucgacu uccgccaaga ccucgggugg aaauggguac acgaacccaa aggcuacuac     1020

gccaacuucu gcagcggacc augcccauac cucagaagcg cagacacaac acacuccacc     1080

guccucggcc ucuacaacac ccuaaacccc gaagccucag ccucccccug cugcguacca     1140

caagaccuug aaccacucac cauccucuau uacguaggcc gcacccccaa agucgaacaa     1200

cucucaaaca uggucguaaa aucaugcaaa ugcuccuaa                            1239


<210>  1174
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  1174
auggcaccag ucgcagucug ggccgcccuc gccguaggcc uugaacucug ggcagccgcc       60

cacgcccucc cagcacaagu cgcauucacu cccuacgcac ccgaacccgg cuccaccugc      120

cgccuacgcg aauacuauga ccaaacagca caaaugugcu gcuccaaaug cucucccggc      180

caacacgcua aaguauucug cacaaaaacc ucugacaccg uaugcgacuc augcgaagac      240

uccacauaua cccaacucug gaacuggguc cccgaaugcc ucuccugcgg cucccgcugc      300

agcucagacc aaguagaaac ccaagcuugc acccgcgagc aaaaccgcau cugcacaugc      360

cgccccggcu gguacugcgc ucucuccaaa caagaaggcu gcagacuuug ugcaccucug      420

aggaaaugcc gaccaggcuu ugguguagca agacccggua ccgaaaccuc agacgucguc      480

ugcaaaccgu gugcacccgg caccuucuca aacaccaccu ccucuaccga caucugccga      540

ccacaucaaa ucugcaacgu agucgccauc ccaggcaacg ccuccaugga cgccguaugc      600

accucgaccu cccccacccg cuccauggcc cccggcgccg uacaccuacc ccaacccguc      660

uccacccgau cccagcacac ccaacccacc ccagaaccca gcaccgcccc gucaaccuca      720

uuccuacucc caaugggccc cuccccaccc gcagaaggcu ccacaggcga uuucgcccuc      780

cccguaggac uaauaguugg cgucaccgcc cuaggccucc uuaucaucgg cguagucaac      840

ugcgucauca ugacccaagu caaaaaaaaa ccccucugcc uccaacgcga agccaaaguc      900

ccacaccucc cagccgacaa agcccgcgga acccaaggcc ccgaacaaca acaccugcuc      960

aucaccgccc ccucaucaag cuccuccuca cucgaaucau ccgccuccgc ccucgaucga     1020

cgcgccccca cacgcaacca accacaagcc ccaggcguag aagcguccgg cgccggcgaa     1080

gcccgcgccu ccaccggcuc guccgacucc ucaccaggag gucacggcac ccaaguaaau     1140

gucaccugca ucgugaacgu uuguuccucc ucagaucaca gcucccaaug cucuucccaa     1200

gccuccucca caaugggcga caccgauucc agccccucag aaucccccaa agacgaacaa     1260

gucccauucu caaaagaaga gugugccuuc cgaucccagc ucgaaacacc agaaacccua     1320

cucgguucaa ccgaagaaaa accccucccc cucggcgucc cagacgcagg caugaaaccc     1380

uccuaa                                                                1386


<210>  1175
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  1175
augccgguca ugcgccuguu cccgugcuuu cuccagcuac uggccgggcu cgcgcucccg       60

gccgugcccc cgcaacaaug ggcgcucucg gccggaaacg ggagcucgga aguggaagug      120

gucccguucc aggaagugug ggggcgcucg uacugucgag cgcucgagcg cuuggucgau      180

gucgugagcg aguacccgag cgaggucgag cacauguucu cgcccucgug cgugagcuug      240

cuaaggugca cgggauguug cggggacgag aacuugcacu guguaccggu cgagaccgcg      300

aacgugacca ugcaauugcu caagaucagg agcggggaca ggcccucgua cguggaauug      360

accuuuagcc agcacgugcg cugugaaugu cgcccgcuca gggaaaagau gaagccagag      420

cgcaggcgcc cgaaagggcg agggaaaagg cgcagggaaa agcaaagacc cacggacugu      480

cacuugugcg gggacgcggu cccgaggcgc uga                                   513


<210>  1176
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  1176
augaccgaua gacagaccga cacagcgccc ucacccucgu accaucucuu gccggggagg       60

aggagaacgg uagacgcggc ggcaucgcgc gggcaagggc cggaaccagc gccaggggga      120

ggagucgaag gagugggagc gagagggguc gcgcuaaaac ucuucgucca acugcuggga      180

ugcagcaggu ucgggggagc agugguaaga gcaggagagg cagagccauc gggcgcggca      240

aggagcgcaa gcucgggaag ggaggaacca cagccagaag aaggggaaga ggaagaggaa      300

aaggaagaag aaaggggacc acaauggaga cuaggcgcga gaaagccagg gagcuggaca      360

ggggaggcgg ccgugugcgc ggacucggca ccagccgcaa gagcgccgca ggcacuagca      420

agggccucgg gaaggggagg aaggguggca agacgaggag ccgaggaauc aggaccacca      480

cacagcccaa gcaggcgagg gagcgcgagc agggcagggc ccgggagagc aagcgagaca      540

augaacuuuc ucuugagcug gguacauugg ucgcuagcgc uccuacugua ucugcaccac      600

gcgaaaugga gccaggcagc gccaauggca gagggaggag ggcagaacca ccacgaaguc      660

gugaaauuca uggauguaua ccaaaggagc uacugccacc caauagaaac gcuaguagac      720

auauuccagg aauauccaga ugaaauugaa uacauauuca aaccgagcug cguaccacuc      780

augaggugug gcggaugcug uaacgaugaa gggcuagagu gcgugccaac agaagagagc      840

aacauaacaa ugcaaauaau gcgaauaaaa ccacaccaag gacagcacau aggagagaug      900

agcuuccuac aacacaacaa gugcgagugc aggccaaaga aagacagagc gcgccaagaa      960

aagaaaagcg uaaggggaaa ggggaaggga cagaaaagga aaaggaaaaa gaguagauac     1020

aaaaguugga gcguauacgu aggagcgaga ugcugcuuga ugccgugguc acuaccggga     1080

ccacacccgu gugggcccug cagcgagaga cgaaaacacc uauucgugca ggacccgcag     1140

acgugcaagu gcucguguaa gaacacggac ucgaggugca aagcgagaca gcuagagcug     1200

aaugaaagga ccugccgaug ugacaagccc agaagguag                            1239


<210>  1177
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  1177
augaacuucc uccuaagcug gguccacugg ucccucgccc uacuccucua ccuacaccac       60

gccaaauggu cccaagccgc acccauggcc gaaggcggcg gccaaaacca ccacgaaguc      120

gucaaauuca uggacgucua ccaacgcuca uacugccacc ccaucgaaac ccucgucgac      180

aucuuccaag aauaccccga cgaaauagaa uacaucuuca aacccucaug cgucccccuc      240

augcgcugcg gcggcugcug caacgacgaa ggacucgaau gcguacccac cgaagaauca      300

aacaucacaa ugcaaaucau gcgcaucaaa ccccaccaag gccaacacau cggcgaaaug      360

uccuuccucc aacacaacaa augcgaaugc cgccccaaaa aagaccgagc acgacaagaa      420

aaaaaauccg uccgaggcaa aggcaaaggc caaaaacgaa aaagaaaaaa aucccgcuac      480

aaauccuggu ccguauacgu cggcgcccga ugcugccuca ugccaugguc ccuccccggc      540

ccccacccau gcggccccug cuccgaacgc cgcaaacacc ucuucgucca agacccccaa      600

accugcaaau gcuccugcaa aaacaccgac uccagaugca aagcccgcca acucgaacuc      660

aacgaacgca ccugccgcug cgacaaaccc cgacgcuaa                             699


<210>  1178
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  1178
augucccccc uccuccgccg ccuccuccuc gcagcccuac uccaacuagc ccccgcacaa       60

gcccccgucu cccaacccga cgcccccggc caccaacgca aaguagucuc cuggauagac      120

gucuacaccc gcgccaccug ccaaccccgc gaagucguag ucccccucac agucgaacuc      180

augggcacag ucgccaaaca acucguaccc ucaugcguca ccguccaaag augcggcggc      240

ugcugccccg acgacggccu cgaaugcguc cccaccggcc aacaccaagu ccgcaugcaa      300

auacucauga uccgauaccc aucaucccaa cuaggagaaa ugucacucga agaacacucu      360

caaugcgaau gcagacccaa aaaaaaagac ucagccguaa aaccagaccg cgccgcaaca      420

ccccaccacc gcccccaacc acgaucaguc cccggcuggg acuccgcccc cggcgccccc      480

ucccccgccg acaucaccca ccccaccccc gcccccggcc cauccgccca cgccgccccc      540

uccaccaccu cugcccuaac ccccggcccc gccgccgccg ccgcagacgc cgccgccuca      600

uccgucgcca aaggcggcgc cuaa                                             624


<210>  1179
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  1179
augcaccucc uaggcuucuu cagcguugcc ugcucccuac uggccgccgc ccuccucccu       60

ggcccccgcg aagcucccgc agccgcagca gccuuugaau caggucucga ccuuagcgac      120

gcagaacccg acgccggaga agcuaccgcc uacgcgagca aagaccucga agaacaacug      180

cgauccgucu ccuccgucga cgaacucaug acuguacucu accccgaaua cuggaaaaug      240

uacaaaugcc aacuccggaa aggaggcugg caacacaaca gagaacaagc caaccucaac      300

ucccgaaccg aagaaacuau caaauucgcc gcagcccacu acaacaccga aauacucaaa      360

ucaaucgaca acgaauggag aaaaacccaa ugcaugcccc gagaagucug caucgacguc      420

ggcaaagagu ucggagucgc caccaacaca uucuucaaac caccuugugu auccgucuac      480

cgaugcggag guugcugcaa cuccgaaggc cuacaaugca ugaacaccuc caccucauac      540

cucucaaaaa cacucuucga aaucaccguc ccccuaagcc aaggcccgaa accagucacc      600

auuuccuucg caaaccauac aucaugccga uguaugucaa aacucgacgu cuaccgccaa      660

guccacucca uaauccgacg cucacuccca gccacccucc cccaaugcca agcagcaaac      720

aaaaccugcc caaccaacua cauguggaac aaccacaucu gccgcugccu cgcacaagaa      780

gacuucaugu ucagcuccga cgccggcgac gacuccaccg acggcuucca cgacaucugc      840

ggccccaaca aagaacucga cgaagaaaca ugccaaugcg uuugucgcgc cggccuccgc      900

ccagccuccu gcggaccaca caaagaacuc gacagaaacu ccugccaaug cguuugcaaa      960

aacaaacuau ucccauccca augcggagcc aaccgcgagu ucgacgaaaa uaccugccaa     1020

ugcguaugca aacgaaccug cccccgaaac caaccccuaa accccggcaa augcgcuugc     1080

gaaugcaccg aauccccgca aaaaugccuc cucaaaggaa agaaauucca ccaccaaacc     1140

ugcuccugcu accgccgacc cugcaccaac cgucaaaaag cgugcgaacc cggauucucc     1200

uacuccgaag aagucugccg cugcgucccc agcuacugga aacgccccca aauguccuaa     1260


<210>  1180
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  1180
auguaccgag aaugggucgu cgucaacgua uucaugaugc ucuacguaca acucguccaa       60

ggcagcagca acgaacacgg ccccgucaag agauccagcc aaagcacccu agaacgaucc      120

gaacaacaaa uacgcgcagc cucaagccuc gaagaguuac uacgaaucac ccacucagaa      180

gacuggaagc ucuggcgaug ccgccuccgc cucaaguccu ucaccuccau ggacagcaga      240

ucagccuccc accgcucaac ccguuucgcc gccaccuucu acgacaucga aacccucaaa      300

gucaucgacg aggaauggca acgaacacaa ugcucuccca gagaaaccug cguagaaguc      360

gccuccgaac uugguaaauc aaccaacacu uucuucaaac cacccugcgu caacgucuuc      420

cgcugcggag gcugcugcaa cgaagagucc cucauaugca ugaacacauc caccuccuac      480

aucuccaaac aacucuucga aauauccgua ccccuaaccu ccgucccaga acuuguaccc      540

gucaaagucg ccaaccacac cggcugcaaa ugccucccca cagcaccccg ccaccccuac      600

uccauaaucc gccgaucgau acaaauaccg gaagaagacc gcugcucaca cucaaagaaa      660

cucugcccca uagacaugcu cugggacucc aacaaaugca aaugcguccu ccaggaagaa      720

aacccccuag ccggcacaga agaccacucc caccuccaag aaccagcccu cugcggcccc      780

cauaugaugu ucgacgaaga ccgcugcgaa ugcguaugca aaacccccug ccccaaagac      840

cucauccaac accccaaaaa cugcucaugc uucgaaugca aagaaucacu cgaaaccugc      900

ugccaaaaac acaaacucuu ccaccccgac acaugcucau gcgaagaccg augccccuuc      960

cacacccgcc ccugcgccuc cggcaaaacc gccugcgcca aacacugccg auucccaaaa     1020

gaaaaacgcg ccgcccaagg cccccacuca cgcaaaaauc cauaa                     1065


<210>  1181
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  1181
auggcaguaa uggcaccaag aacauuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg ca                                                           72


<210>  1182
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  1182
auggaugcua ugaaaagagg uuuauguugu guuuuauuau uauguggagc uguauuugua       60

ucuccaucu                                                               69


<210>  1183
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  1183
auggguguac augaaugucc agcuuggcuu uggcuuuuac uuucacuuuu aucuuuaccu       60

uuagguuuac cuguacuugg a                                                 81


<210>  1184
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  1184
augaaauggg uuacuuuuau uucucuucuu uuucuuuuuu cuucugcuua cucu             54


<210>  1185
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from 
       Artificial____cleavage site-Furin

<400>  1185
aggagaagaa ggaaaaga                                                     18


<210>  1186
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  1186
auggauuccg acgaaaccgg cuuugaacac ucaggauuau ggguaucagu auuagcagga       60

cuacuacuag gagcaugcca agcacaccca auaccagacu caucaccauu auuacaauuc      120

ggaggacaag uaagacaaag auaccuauac acagacgacg cucaacaaac agaagcacau      180

uuagaaauaa gagaagacgg aacaguagga ggcgcagccg accaaucacc agaaucuuua      240

cuacaauuaa aagcacuaaa accaggcgua auacaaauau uaggaguaaa aacaucaaga      300

uucuuaugcc aaagaccaga uggagcacua uacggaucac uacacuuuga cccagaagca      360

ugcucauuca gagaauuacu auuagaagac ggauauaacg uauaccaauc agaagcacau      420

ggacuacccc uacaccuacc aggaaacaaa ucaccacauc gagacccagc cccaagaggc      480

cccgcaagau uccuaccacu accaggacua ccaccagcac uaccagaacc accaggaaua      540

uuagcaccac aaccaccaga uguaggaucc uccgacccau uaucaauggu aggaccauca      600

caaggaagau cuccaucaua cgcaucauaa                                       630


<210>  1187
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  1187
augcauucau ucccaccucu auuacuacua uuauuuuggg guguuguauc ccacucauuu       60

ccagcuacau uagaaacaca agaacaagac guagaucuag uccaaaaaua ucuagaaaaa      120

uacuacaacc uaaaaaacga cggacgccaa guagaaaaaa gaagaaacag uggaccagua      180

guagaaaaac uaaaacaaau gcaagaauuu uuuggacuaa aagucacagg aaaaccugau      240

gccgaaacuu uaaaaguaau gaaacaacca agaugcggcg uaccugacgu agcacaauuc      300

gucuuaacag aaggaaaccc aagaugggaa caaacgcacu uaacauaucg aaucgaaaau      360

uacacaccag accuaccaag agcagacgua gaucacgcaa uagaaaaagc cuuccaacua      420

uggucaaaug uaacaccccu aacauucaca aaaguaucag aaggacaagc agauauaaug      480

aucucauucg uaagagggga ucacagagau aacucacccu ucgauggccc aggaggaaac      540

cuagcacacg cauuccaacc uggaccagga auagguggug augcacauuu cgacgaagac      600

gaaagaugga caaacaacuu cagagaauau aaccuacaca gaguagcagc ucacgaacua      660

ggucauucau uaggacuaag ucauucaaca gauauaggag cacuaaugua cccaucauac      720

acuuuuagcg gagacguaca acuagcacaa gacgacauag auggaauaca agcaauauac      780

ggaagaucac aaaaccccgu acaaccaaua ggaccacaaa caccaaaagc augugacuca      840

aaacucaccu ucgacgcaau aacaaccaua agaggagaag uuauguucuu uaaagacaga      900

uucuacauga gaacaaaucc cuuuuaccca gaaguagaau uaaacuucau cucaguauuu      960

uggccccaac uaccaaaugg ucuagaagca gccuacgaau uugcugauag agaugaagua     1020

agauucuuca aaggaaacaa auauugggcc guccaaggac aaaacguauu acacggauau     1080

ccaaaagaua ucuacuccuc auucggcuuu ccaagaacag uaaaacauau ugaugcagca     1140

cuauccgaag aaaacacagg aaaaacauac uucuuuguag ccaacaaaua cuggagauau     1200

gaugaauaca aaagaucgau ggacccagga uaccccaaaa ugauagcaca cgacuuucca     1260

ggaauaggac acaaaguaga ugcaguauuc augaaagacg gauucuucua cuucuuccac     1320

ggcaccagac aauacaaauu ugaccccaaa acaaaacgca uccuaacauu acaaaaagca     1380

aauucauggu uuaacuguag aaaaaacuaa                                      1410


<210>  1188
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  1188
augcacucau ucccaccacu auuauuacua cuauucuggg gaguaguauc acacuccuuc       60

guauuaacug aaggaaaucc ucgaugggaa caaacccacc ucacauauag aauagaaaac      120

uacacaccag accuaccuag agcagacgua gaccacgcaa uagaaaaagc cuuccaauua      180

ugguccaacg ucacaccauu aacuuucacu aaagucucag aaggacaagc agauauaaug      240

auauccuuug ucagaggaga ucacagagac aacucaccau uugacggacc aggaggaaau      300

cuagcacacg cauuccaacc cggacccgga auagguggag acgcacacuu cgaugaagau      360

gaaagaugga caaacaauuu cagagaauac aauuuacaca gaguagcagc acacgaacuc      420

ggacacuccu uaggacucuc ccauucaacc gacauaggag cauuaaugua cccaucauac      480

acauucucag gagacgucca acuagcacaa gacgauaucg acggcauaca agcuauauac      540

ggaagaucac aaaacccagu acaaccaauc ggaccacaaa caccaaaagc cugugacuca      600

aaauuaacuu uugaugcaau cacaacuaua cgaggcgaag uaauguuuuu caaagacaga      660

uucuacauga gaacaaaccc cuuuuacccu gaaguagaac uaaacuucau aucuguuuuc      720

uggccacaac uaccaaacgg auuagaagca gcauacgaau uugccgacag agacgaaguu      780

agauucuuca aaggaaacaa auacugggca guucaaggac aaaacgucuu acacggauau      840

ccaaaagaua uauacuccuc auucggauuc ccaagaaccg uaaaacacau cgaugccgca      900

uuaucagaag aaaauacagg caaaacauac uucuuuguug caaacaaaua uuggagauac      960

gacgaauaca aacgcucuau ggacccaggc uauccaaaaa ugauugcaca cgauuuccca     1020

ggaauaggac acaaaguaga ugcaguauuc augaaagacg gauucuuuua uuucuuccac     1080

ggaacaagac aauacaaauu cgauccaaaa acaaaaagaa uccuaaccuu acaaaaagcc     1140

aacucauggu ucaauugcag aaaaaauuaa                                      1170


<210>  1189
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  1189
augaagaaaa acauacugaa aaucuuaaug gacuccuacu ccaaagaauc aaaaauccaa       60

acaguaagac guguaacauc aguaucacuc cuggcaguau accuuacaau gaacacuucu      120

uccuuaguau uagccaaacc aauagagaau acuaaugaca caucaaucaa aaauguagaa      180

aaauuacgaa augcacccaa cgaagaaaac agcaagaaag uagaagauuc caaaaacgac      240

aaaguagaac auguuaaaaa cauagaagaa gcuaaaguag aacaaguugc uccggaagug      300

aaaucaaaau caacguugag aagugcaagu auagcaaaca ccaacuccga aaaauaugac      360

uucgaauacu uaaauggacu aucguacaca gaauuaacaa auuuaauuaa aaacauaaaa      420

uggaaucaaa uaaauggucu guucaacuau aguaccggcu cccaaaaauu cuucggagau      480

aaaaaucgug uucaagcuau aauaaaugca cuacaagaau cugguagaac auauaccgcu      540

aacgauauga aaggaauaga gacuuuuacg gaaguccuaa gagccggauu cuacuuagga      600

uacuauaacg augguuuaag uuauuuaaau gacagaaauu uucaagacaa augcauaccg      660

gcaaugauag caauacagaa aaacccuaac uuuaagcuag gaacagcugu ccaagacgaa      720

guaauuacau cacuagguaa acuuaucgga aaugcaagcg caaacgcaga agucguaaau      780

aauugugucc caguacuaaa acaauuuaga gaaaauuuaa accaauaugc uccagacuau      840

guaaaaggaa cagcaguaaa ugaacuuaua aaagguauag aguucgacuu cucaggagca      900

gcauaugaaa aagacguaaa aacaaugcca ugguauggaa aaaucgaucc auuuauaaau      960

gaauugaagg cauuaggccu auauggaaau auaaccagcg cgacagaaug ggcaucagac     1020

gucggaauuu acuaccuuag uaaauucgga cuauauagca caaauagaaa ugacauagua     1080

caaagccucg aaaaagcggu agauauguac aaauauggaa aaauagcuuu cguagccaug     1140

gaacgaauaa caugggacua ugaugguaua gguucaaacg gaaagaaagu cgaccacgau     1200

aaauuccuag acgaugcuga aaaacacuac uuaccaaaaa ccuacacguu cgauaaugga     1260

acuuuuauaa uacgugcugg agacaaaguu ucagaagaga aaaucaaaag auuauauugg     1320

gcuucgcgag aaguaaaauc ucaauuccac cgaguaguag gaaacgauaa agcauuagaa     1380

guuggaaaug cggacgaugu auuaacaaug aaaauuuuca acucacccga agaauauaaa     1440

uuuaauacua acauuaacgg uguaagcaca gauaacggag guuuauacau agaaccucga     1500

ggaacauuuu auacguauga acgaacacca caacaaagca uauuuucguu agaagaacua     1560

uuuagacaug aauauacaca uuaccuacaa gcacgauacu uaguagaugg auuauggggu     1620

caaggacccu uuuacgaaaa gaaucgccuc acaugguucg augaaggcac cgcugaguuc     1680

uuugcuggcu cgacgagaac aaguggagug cucccaagaa aaaguaucuu aggauaccuu     1740

gcaaaagaua agguugacca ucguuauuca cuaaagaaaa cuuuaaauuc agguuacgac     1800

gacagugauu ggauguuuua caauuacgga uuugcaguag cacauuaucu cuacgaaaaa     1860

gacaugccca ccuuuauaaa aaugaauaaa gcaauuuuaa acaccgaugu aaaauccuac     1920

gaugaaauaa uuaagaaacu gagugaugac gccaacaaaa auaccgaaua ucaaaaucac     1980

auccaagaau uagccgacaa auaccaagga gcagguauac cgcuagugag ugaugacuau     2040

cucaaagacc acggcuauaa gaaagcaucu gaaguuuacu ccgaaauuag caaagcggca     2100

ucacucacca auacuagcgu caccgcagaa aaaucccaau acuuuaauac auuuacucuu     2160

cgaggcacau acacaggaga aacgagcaaa ggagaauuua aagacuggga cgaaaugagu     2220

aagaaacucg auggaacauu agaaucauua gccaaaaacu ccuggagugg cuacaaaaca     2280

cuuacugcau acuucacaaa uuauagagua acaagugaua auaaaguaca auaugaugua     2340

gucuuucacg guguauuaac agauaaugca gauauaucaa acaacaaagc accaauagca     2400

aaaguaacug gaccaucaac aggggcuguc gggagaaaua uugaguucuc aggcaaagau     2460

ucaaaagacg aagaugguaa aauuguuucg uacgauuggg auuuuggcga cggagcaaca     2520

agucguggua aaaacagugu acaugccuac aagaaagccg gaaccuacaa uguaacauua     2580

aaaguaaccg acgacaaagg agcaaccgcc acagaaaguu uuacuauaga aauuaaaaau     2640

gaagacacaa caacccccau aacuaaagaa auggaaccaa acgacgacau aaaagaagca     2700

aauggaccga ucguagaagg aguuaccguu aaaggagacu uaaacggcuc agaugacgca     2760

gauacuuuuu acuucgaugu caaagaagac ggagauguca caauagaauu acccuacagu     2820

ggaucuucaa acuuuaccug gcuagucuau aaagaaggag augaccaaaa ucauauagca     2880

agcggaauag auaaaaacaa cagcaaagua ggcacauuca aaaguacaaa aggcaggcau     2940

uacguauuua uauacaaaca cgauucugcc ucaaacauuu cuuacaguuu aaauauuaaa     3000

ggucuaggaa augaaaaacu aaaagaaaaa gaaaacaacg acucaucuga caaagcaaca     3060

guaauaccua acuucaacac aacaaugcaa ggaucauuac uaggagauga caguagagau     3120

uacuauucau uugaaguaaa agaagaaggu gaaguaaaua ucgagcuaga uaagaaagac     3180

gaauuuggag ugacauggac ccuucaccca gaaucaaaua uaaacgaucg aauaacauau     3240

ggacaagucg auggcaacaa aguaucaaau aaaguuaaau uaagaccagg aaaauauuau     3300

cuccuuguau acaaguauuc aggcagugga aacuaugaau ugagaguaaa caaauga        3357


<210>  1190
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  1190
augaaauggg ucacauuuau uucacuacug uuuuuauucu caucagcaua uaguauagca       60

aauacaaaca gugaaaaaua cgauuucgaa uaucucaacg gauugucaua uacagaacuu      120

accaaccuua uuaaaaauau aaaauggaac caaauaaaug gucuauuuaa uuacaguacg      180

gguucgcaga aauucuuugg agauaaaaac cguguacagg ccauaauaaa cgcacuacag      240

gaauccggac gcaccuauac ggcuaaugau augaaaggaa uagaaacuuu uacugaagua      300

cuaagagccg gauuuuaucu cggauauuac aaugauggau ugaguuaccu aaacgauagg      360

aacuuucaag acaaauguau uccagcaaug auagcaauac agaaaaaccc caacuucaaa      420

uuaggcacag ccguacaaga cgaaguuaua acuucauuag gaaaauuaau cgguaacgca      480

agcgcaaacg ccgaaguagu aaauaauugu guaccaguac uaaaacaauu cagagaaaac      540

cucaaccaau acgcacccga uuacguaaaa gggacagcag uaaaugaauu aauaaaaggu      600

aucgaauuug acuucuccgg agcagcuuau gaaaaagacg uuaaaacuau gcccugguac      660

ggaaaaauag auccuuuuau aaaugaacuc aaagcauuag gacucuaugg gaauauaaca      720

ucggcuacug aaugggccag cgacguagga auauauuauu uaucaaaauu ugggcuauac      780

ucaacgaaca ggaaugauau aguacaaucg cuagaaaaag ccguagacau guauaaauau      840

gguaaaauug cauucgucgc aauggaaaga auuacauggg auuaugacgg aauagggucc      900

aacggcaaga aaguagauca cgauaaauuu uuagacgacg cugaaaaaca uuauuuacca      960

aaaacauaua cuuuugacaa cgguacauuc aucauuaggg caggagauaa aguuuccgaa     1020

gagaaaauaa aaagauuaua cugggcaagu cgagaaguaa aaucacaauu ccacagagua     1080

guaggcaacg auaaagccuu agaagucggu aaugcugacg auguauuaac caugaaaaua     1140

uucaacaguc cugaagaaua caaauuuaau accaauauaa auggaguaag uaccgauaau     1200

ggcggacuau acauagaacc ucgaggaacc uucuacacgu acgaacgaac uccgcaacaa     1260

ucaauauuua gucuagaaga acuauuucgg caugaauaua cgcacuacuu acaagcuaga     1320

uaucuuguag acggauuaug ggggcaagga cccuucuaug aaaagaaucg auuaacaugg     1380

uuugacgaag gaacugcuga auuuuucgca gguucaacaa gaacgucagg aguacuacca     1440

aggaaaagua uacuaggcua ccuugcaaaa gauaaaguug aucaucgaua uucacuaaag     1500

aaaacacuaa auagugguua ugacgacuca gauuggaugu ucuauaacua ugguuuugca     1560

guggcacauu aucuauauga aaaagauaug ccaaccuuca uaaaaaugaa caaagccaua     1620

uuaaauacug acgucaaauc auacgacgaa auaauuaaga aauuaucaga cgaugcaaac     1680

aaaaauacag aauaucaaaa ccauauacaa gaauuagcag auaaauauca aggugcaggu     1740

auuccauuag uaucggauga uuauuuaaaa gaucauggau acaagaaagc cagcgaagua     1800

uacucugaaa uuagcaaagc agcgucacuc acgaauacau cuguuacugc agaaaaauca     1860

caauauuuua auacauuuac acugcgugga accuauaccg gagaaacauc aaaaggugaa     1920

uuuaaagacu gggacgaaau gucaaagaaa cuagauggaa cccucgaaag uuuagccaaa     1980

aauucaugga guggauauaa aacucuuacu gcauacuuca cuaauuacag aguaacauca     2040

gacaacaaag uacaauacga cguaguauuu cauggcgucu ugacagauaa ugccgacauu     2100

ucaaauaaca aagccccaau agcuaaagug acaggaccau caacaggcgc agucggaaga     2160

aauauugagu ucucagggaa agauaguaaa gacgaagaug gaaaaauagu uagcuaugac     2220

ugggacuucg gagauggagc aacaucucga gguaaaaacu ccguacacgc auauaagaaa     2280

gcuggaaccu auaacguuac auuaaaagua acugaugaua aaggagcaac ugcaacagaa     2340

aguuuuacua uagaaaucaa aaacgaagau accacaacac caauaacaaa agaaauggaa     2400

ccaaacgacg acauaaaaga agcgaaugga cccauaguag aaggagucac uguuaaagga     2460

gacuuaaaug ggagcgacga ugccgacacu uuuuauuucg acguuaaaga agauggagac     2520

guaacuauag aauuacccua cucuggaagu aguaauuuua ccuggcuagu auacaaagaa     2580

ggcgaugauc aaaaccauau agcgucagga auagauaaaa auaauucaaa agugggcacu     2640

uucaaaagca caaaaggaag acauuacgua uucauuuaua aacacgauuc agcaucaaac     2700

auaucauacu cgcuuaauau aaaaggacua ggaaacgaaa aacuuaaaga aaaagaaaac     2760

aaugacucau cagacaaagc cacaguaauu ccaaauuuua acacuacuau gcaaggaagc     2820

cuuuuaggag augauaguag agauuauuau ucauucgaag uaaaagaaga aggagaaguu     2880

aauaucgaac uagauaagaa agaugaguuc gguguaacgu ggacauuaca cccugaaucc     2940

aauauuaacg acagaaucac cuauggacaa guugacggaa auaaagucag caacaaaguu     3000

aaauuaagac ccggaaaaua uuaccuccua guuuauaaau auagcggauc aggaaacuac     3060

gaauuacgag uaaauaaaug a                                               3081


<210>  1191
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  1191
augaaauggg uaacauucau aucauuacuu uuccuauuuu caucagcaua caguaugaag       60

aaaaauauau uaaaaauauu aauggacagc uauagcaaag aaucaaaaau acaaacaguu      120

agaagaguaa cuagcguuag cuuauuagcc guauacuuaa caaugaauac aaguagccua      180

guauuagcaa aaccgauaga aaauacaaac gacacgagca ucaaaaacgu ugaaaaacua      240

agaaaugccc ccaacgaaga aaacaguaag aaagucgaag acaguaaaaa ugauaaagua      300

gaacauguga aaaacauaga agaagccaaa guagaacaag uagccccuga aguuaaaagc      360

aaaucaacgc uacgcagcgc caguaggaga agaagaaaaa gaauagcaaa uacuaacuca      420

gaaaaauaug acuucgaaua cuuaaaugga cuaaguuaca cagaacuuac caaucuuauc      480

aaaaacauaa aauggaauca aauaaaugga cuauucaauu auuccacugg gucacaaaaa      540

uuuuucggag auaaaaauag agugcaggcu auaauuaacg cacuacaaga aucaggaaga      600

accuacacag caaacgauau gaaagggaua gaaacuuuca cugaaguacu gcgagcggga      660

uucuauuugg gguacuauaa cgacgguuua ucauacuuaa acgacagaaa uuuucaagac      720

aaauguauac cagcaaugau agcaauacag aaaaauccua auuuuaaacu agggaccgca      780

guacaagacg aagugauaac aucacucggu aaacucauag gaaaugcuuc agcuaaugcg      840

gaaguaguaa auaauugcgu accaguuuua aaacaauuca gagaaaaccu caaccaauau      900

gcacccgacu auguaaaagg aacugcaguu aacgaacuua ucaaaggaau cgaauuugau      960

uuuagcggag ccgcguacga aaaagacgug aaaacaaugc cuugguaugg aaaaauagac     1020

ccauucauua acgaauuaaa agccuuaggc cuguacggua auauaacuuc agccacagaa     1080

ugggcaagug acguuggcau auacuauuug ucgaaauuug gauuguauuc aacaaaccgu     1140

aacgacauag uucaaagccu ggaaaaagca guagauaugu acaaauaugg aaaaauagcc     1200

uuuguagcaa uggaaaggau uacaugggau uaugacggaa uaggcucaaa ugguaagaaa     1260

guagaucaug auaaguuucu agacgaugca gaaaaacacu aucuuccaaa gacauacacc     1320

uucgacaaug gaacuuuuau uauaagggca ggcgacaaag uauccgaaga gaaaauaaaa     1380

cguuuauacu gggcaucacg ggaaguaaaa agccaauuuc auagaguagu aggaaacgac     1440

aaagcauuag aaguaggaaa cgcagaugac guacucacaa ugaaaauauu caauucuccu     1500

gaagaauaua aauucaauac aaauauaaau ggagucagua cagacaaugg aggacuauac     1560

auagaaccua gagggacauu uuauacuuac gaaagaacac cccaacaauc cauauuuucc     1620

cuagaagaau uguuccgaca ugaauacaca cauuauuuac aagcccgaua cuuaguagac     1680

ggauuauggg gacaaggucc auucuacgag aaaaacagau ugacaugguu cgacgaagga     1740

acagcagaau uuuucgccgg aucaacuaga accuccggug uauuaccaag aaaauccauc     1800

cuuggguacu uagcaaaaga uaaaguagau caucguuauu cguuaaagaa aacauuaaau     1860

agcggcuacg augauucaga uuggauguuu uauaauuaug gcuuugcugu agcacauuau     1920

cuauacgaaa aagauaugcc aacuuucauc aaaaugaaca aagcgaucuu aaauacagac     1980

guuaaaucau augacgaaau cauaaagaaa uuaucagaug augcaaauaa aaacacagaa     2040

uaucaaaacc acauacaaga acuagcugau aaauaucagg gugcaggaau cccacucgua     2100

ucggacgauu accuaaaaga ccauggauau aagaaagcaa gcgaaguaua cucagaaauu     2160

aguaaagcug caucucuuac aaauacaagc guaacggcag agaaaagcca auauuucaac     2220

acguucacac uacgcggaac auauacugga gaaacaagua aaggagaguu caaagauugg     2280

gacgaaaugu caaagaaauu agaugguacu uuagaaucau uagccaaaaa uagcuggucc     2340

ggguacaaaa cacuuaccgc auacuuuaca aauuauagag ucacaagcga uaauaaaguu     2400

caauacgaug ucgucuuuca cggaguacua acagacaacg cggauauaag caauaauaaa     2460

gcaccaauag caaaaguaac aggaccauca accggagcug uuggaagaaa cauugaguuc     2520

ucaggaaaag acucaaaaga cgaagauggc aaaauaguaa gcuaugauug ggauuuugga     2580

gacggcgcaa cauccagagg caaaaauagc guccaugccu auaagaaagc aggaacauac     2640

aacguaacau uaaaaguaac agacgacaaa ggagccaccg ccacugaaag uuuuacuauc     2700

gaaaucaaaa augaagauac aaccacccca auaaccaaag aaauggaacc uaaugaugac     2760

auaaaagaag cuaaugggcc aauuguagaa ggagucacag ucaaaggcga cuuaaacggg     2820

agcgacgacg cugauaccuu cuacuuugac guaaaagaag auggagaugu aacaauagaa     2880

cuaccauauu cagguucauc caauuuuaca uggcuagugu acaaagaagg ugacgaccaa     2940

aaccauauag ccaguggaau ugacaaaaac aauucuaaag uggggacuuu uaaaagcaca     3000

aaagguagac auuauguauu uauauacaaa caugauagug caagcaacau aucauacucu     3060

cuaaauauca aaggcuuagg aaacgaaaag cuaaaggaaa aggaaaauaa cgauuccuca     3120

gauaaagcaa cugugauccc aaauuucaac acuacuaugc aaggcagccu ucucggugau     3180

gauagccgag auuacuacuc cuuugaaguc aaagaagaag gugaagucaa cauagaauug     3240

gauaagaaag augaguucgg cgucacaugg acacugcauc cagaaucaaa cauaaacgau     3300

agaaucaccu acggacaagu cgacggaaau aaaguaagca auaaagucaa auuaagacca     3360

ggaaaauacu accuucuagu auauaaauac ucuggaagug gaaauuacga auuacgaguu     3420

aauaaauaa                                                             3429


<210>  1192
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  1192
augaacuuuu ugaagauaau acuaaauaga ggaaaaacaa ugaaaagaaa augccuaucc       60

aaacgauuaa ugcuggccau aacuauggca acaauauuua caguaaacag uacauuaccu      120

auauaugcag cuguagauaa aaacaacgcu acagcugccg uccagaacga aucuaaaagg      180

uacaccguau cuuaucuaaa aacucuaaac uacuaugacu uaguagauuu gcuaguaaaa      240

acagaaauag agaaucuacc agacuuauuu caauauucaa gcgaugccaa agaguucuau      300

ggaaauaaaa ccagaaugag uuuuauaaug gaugaaauag guagacgagc accacaauac      360

acagaaaucg accauaaggg aauaccgaca cuuguagaag ugguaagagc aggauucuau      420

uuaggauucc auaauaaaga auuaaacgag auaaacaaac gauccuuuaa agaaagaguc      480

auaccaagca uauuagcaau ccagaaaaau ccaaauuuca agcuaggaac agaaguacaa      540

gauaaaauug uaagcgcaac aggauuacuc gcagggaacg aaacagcacc cccagaaguc      600

gugaacaacu ucaccccaau acuccaagac uguaucaaaa auauagauag auacgcacua      660

gaugaccuaa aaaguaaagc ccuuuucaac guacuugcag caccaaccua ugauauaacu      720

gaauaccuac gagcaacaaa agagaaacca gaaaacacac ccugguacgg gaaaauagac      780

ggcuuuauaa augaguuaaa gaaauuagcc uuauauggua aaauaaauga uaauaauuca      840

uggauaauag acaacggcau uuaucauauc gcaccucugg gaaaauuaca caguaauaac      900

aaaauaggua uugaaacacu aacagaagua augaaaguuu auccauaucu aagcaugcaa      960

caccuccaau cagcagauca aauaaaacga cacuacgacu cuaaggacgc agaagggaac     1020

aaaauaccac uagacaaauu caagaaagaa ggaaaagaaa aauacugccc aaaaacauau     1080

acauucgacg auggcaaagu aauuaucaaa gcuggcgcaa ggguagagga agaaaaagua     1140

aaacgucuau auugggcuuc aaaagaagua aauucacaau ucuuucgagu uuacggaauu     1200

gauaaaccau uagaagaagg aaacccagau gacauucuaa cuaugguuau auauaauuca     1260

ccagaagaau auaaacuaaa cucaguauua uacggauaug auaccaacaa cggugggaug     1320

uacauagaac ccgaaggaac auucuuuacu uaugaacgcg aagcacaaga aagcacuuac     1380

acguuagaag aacuauuccg acacgaauau acacauuacu uacaaggacg cuaugcaguu     1440

ccaggacaau ggggacgaac aaaauuauau gauaacgaca gacuaacaug guacgaagaa     1500

ggaggagcag aauuauuugc ugguaguacu cgaacaagug gaauacuacc cagaaaaagc     1560

auuguaagca acauacauaa uacaacacgc aacaacagau auaaacuauc agauacugua     1620

cauuccaaau auggcgccag cuuugaguuc uacaacuacg caugcauguu cauggacuac     1680

auguacaaua aagacauggg uauacucaac aaacuaaacg aucucgccaa aaauaacgac     1740

guugacggau augauaauua cauuagagac cucaguucaa auuaugcauu aaaugacaaa     1800

uaccaagauc acaugcaaga aagaauagau aacuaugaaa acuuaacagu accauucguu     1860

gcagacgauu acuuaguaag acacgcauau aaaaacccua acgaaauaua uucggaaauu     1920

ucagaaguug caaaauuaaa agaugcaaaa ucugaaguaa agaaaaguca auauuuuucg     1980

accuucacau uacguggaag cuauacagga ggugcaucca aaggaaaacu cgaagaucaa     2040

aaagcaauga acaaauuuau agacgacucu uuaaagaaac uagacacaua uucguggagc     2100

ggguacaaaa cauuaacggc auacuucacg aauuauaaag uugacaguuc aaauagaguc     2160

acauaugaug uagucuuuca cggauaccua ccuaacgaag gagacaguaa aaauagucuc     2220

cccuauggga aaauaaaugg cacauacaaa gguaccgaga aagagaaaau aaaauuuucc     2280

ucggaaggcu cauucgaccc ugauggaaaa auaguaucau acgaauggga cuucggagau     2340

ggaaauaaaa guaacgaaga aaauccagaa cacucauacg auaaaguagg gaccuauacc     2400

guaaaacuca aaguaacaga ugacaaaggc gaaagcucag uuucaacaac aacugcagaa     2460

auuaaagauu uaucagaaaa uaaauuacca guaauauaua ugcauguacc aaaaaguggg     2520

gcacuaaauc aaaaaguagu guucuauggg aaaggaacau augauccaga cggaucaauu     2580

gcagguuacc aaugggauuu uggagauggu ucagauuucu caagugaaca aaauccaucc     2640

cacguuuaua caaagaaagg agaauacaca guaacuuuac gaguaaugga caguucaggg     2700

caaaugucgg agaaaacaau gaaaauuaaa auaacagauc caguauaccc aauaggaaca     2760

gaaaaagaac cuaauaauuc aaaagaaacu gcaucagggc caauaguacc cggaauaccc     2820

guauccggua cuauagaaaa cacaucagau caagacuacu ucuauuuuga uguuauaacg     2880

ccaggagaag uaaaaauaga uaucaacaag cuaggauaug gaggagcaac guggguagug     2940

uaugaugaaa auaauaacgc aguuucauau gcaacugacg auggacaaaa ccucuccgga     3000

aaauucaaag cagauaaacc aggaagguau uacauacacc uguacauguu caauggcucu     3060

uauaugccgu aucguauaaa uaucgaaggg ucaguaggaa gauaa                     3105


<210>  1193
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  1193
augaaacgaa aaugcuuauc aaaaagauua auguuagcaa uaacaauggc cacuauauuc       60

acugucaauu caacccuucc aauauacgcc gcaguagaca agaacaaugc uacagcagca      120

guacaaaaug aaaguaagag auacacagua ucguaucuaa aaacucuaaa cuauuaugac      180

cucguggacc ugcuaguaaa aacagaaaua gaaaauuuac cugauuuauu ccaguauuca      240

ucagaugcaa aagaguucua uggcaauaag acaagaaugu ccuucauaau ggaugaaaua      300

ggcagacgag caccacaaua cacugaaauu gaccacaagg gaauaccaac ccuagucgaa      360

guagucagag caggauucua ccuaggcuuc cauaauaagg aacuaaacga aauaaacaaa      420

agaaguuuca aagaaagagu gauaccauca auauuagcaa uacagaaaaa ucccaacuuu      480

aaacuuggaa cagaaguaca agacaaaauu gugagcgcaa ccggauuacu agcagggaac      540

gaaacagcac cucccgaagu agugaauaau uuuacgccaa uauuacaaga uugcauuaaa      600

aacauagaca gauaugcacu agaugauuua aaaucuaaag cauuauuuaa cguacuagca      660

gcucccacau augauauaac agaauaccuc agagccacca aagaaaaacc ugaaaauaca      720

ccaugguaug gaaaaaucga cggcuuuauc aaugaacuua aaaagcuagc acuauaugga      780

aaaaucaacg auaacaacuc auggaucaua gauaauggaa uauaccauau agcacccuua      840

ggcaaacuuc acucaaacaa uaaaaucggc auagaaacau uaacggaagu aaugaaagua      900

uacccuuauc uaucuaugca acauuuacaa ucagcagauc aaauaaaacg ccacuacgau      960

aguaaagaug cagaaggaaa caaaauaccc cucgacaagu ucaagaaaga aggaaaagaa     1020

aaauauuguc caaaaacaua uacguucgac gauggaaaag uaauaauaaa agcaggagca     1080

agaguagaag aggaaaaagu aaaaagauua uacugggcgu caaaagaagu aaacucacaa     1140

uucuucagag uuuauggaau agacaaacca uuagaggaag gaaaucccga ugacauucuu     1200

accaugguga ucuacaacag uccugaagaa uauaaacuaa auucuguccu cuacggauau     1260

gauacaaaca acggaggcau guauaucgaa ccagaaggaa ccuuuuucac auaugagaga     1320

gaagcucaag aaucaaccua cacccucgag gaacuauuca gacacgaaua uacgcacuau     1380

cuacaaggca gguacgcagu acccggacaa uggggccgua caaaacuaua ugacaacgac     1440

agacuaacuu gguacgaaga aggaggggcu gaauuauuug ccggaucaac aagaaccuca     1500

gggauucuuc cacgaaaauc gauaguuucg aauauacaca auacaaccag aaacaauaga     1560

uauaaauuau cagauacagu gcauuccaaa uauggggcuu cauucgaguu uuacaauuau     1620

gcuugcaugu ucauggauua uauguauaac aaagacaugg gaauacucaa caaacuaaau     1680

gaccucgcua aaaacaauga cguagaugga uacgacaauu acauacgcga uuuaagcucc     1740

aacuaugcau uaaacgacaa auaucaagau cauaugcaag aaagaauaga uaauuaugag     1800

aaucuaacag uaccguucgu cgcagaugau uacuuagugc ggcacgcaua uaaaaacccu     1860

aaugaaauuu auagcgaaau aagugaaguu gcaaaauuaa aagacgcaaa aagugaagua     1920

aagaaaucac aauacuuuag cacauucaca uuaagaggaa guuauacugg aggagccucc     1980

aaagguaaac uagaagacca aaaagcuaug aacaaauuua uagaugauag ucuuaagaaa     2040

cuugacaccu auucauggag uggauauaaa acauuaacag cuuauuucac uaacuauaaa     2100

guagauucau caaaucgcgu aacuuaugau gucguuuucc acgguuauuu acccaacgaa     2160

ggagacagua aaaacucacu accauacggu aaaauaaaug gcacuuacaa aggaacagaa     2220

aaagagaaaa uaaaauucag uucugaagga ucauucgacc cagauggaaa aauagugagc     2280

uaugaauggg acuucggaga ugguaauaaa agcaaugaag aaaauccaga acacaguuau     2340

gacaaaguag guacauacac uguuaaauua aaagucacag acgauaaagg cgaaaguuca     2400

guaucaacaa caacagccga aauaaaagau cuaagcgaaa acaaacuacc cgucauauau     2460

augcacguac cuaaaagugg agcccuuaac caaaaagugg uauucuacgg aaaaggaaca     2520

uacgacccug acggaagcau agcaggauau caaugggacu ucggugacgg uucggacuuc     2580

ucuucugaac aaaauccaag ccacguauac acaaagaaag gagaauacac cguaacacuu     2640

agaguuaugg acagcucagg acaaauguca gagaaaacaa ugaaaaucaa aauuaccgac     2700

ccuguauauc caauaggaac ugaaaaagaa ccaaauaaca guaaagaaac agcuagugga     2760

ccgaucguuc cagguauucc uguaagugga acaaucgaaa acacaucaga ccaggacuau     2820

uuuuauuucg auguaauaac accaggagaa gucaaaaucg auauaaauaa acuaggauau     2880

ggaggggcua cauggguagu auacgaugaa aacaacaaug caguauccua cgcgacagau     2940

gacggacaga accuuucagg aaaauucaaa gcggacaaac caggcaggua cuacauacac     3000

cuauacaugu ucaacggauc cuauaugccu uaucgaauua auauagaagg auccguaggc     3060

cguuaa                                                                3066


<210>  1194
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  1194
augaaauggg ugacauucau aucucuacuu uuccuauucu ccucagcaua cucaguacaa       60

aacgaaucaa aaagauacac agugaguuac uuaaaaacgu uaaacuacua ugaccuagua      120

gaccuucuag uaaaaaccga aauagaaaau cuaccagacc uauuccaaua cucuucagau      180

gccaaagaau uuuauggaaa uaaaaccaga augaguuuca ucauggauga aaucggaagg      240

agagcaccac aauacacgga aauagaucac aaagguauac ccacuuuagu agaagucgua      300

agagcaggau ucuacuuagg auuccauaac aaagaacuca augaaauuaa uaaaagaucu      360

uucaaagaaa ggguaauacc cagcauacuc gccauacaga aaaaccccaa cuucaaacua      420

ggaacagaag uacaagauaa aauaguauca gcaacugguu uacucgcugg aaaugaaacc      480

gcaccaccag aaguaguaaa caacuucacc ccuauucuac aagacugcau uaaaaauaua      540

gacagauacg cccuagacga cuuaaaaucg aaggcccucu uuaacguacu agccgcccca      600

acauaugaua uaacagaaua cuuaagagca accaaagaaa aaccagaaaa uacacccugg      660

uacggaaaaa uagacggauu uauaaaugaa uuaaagaaau uagcguuaua ugggaaaaua      720

aacgacaaua auaguuggau aauagacaac ggaauauacc acauagcacc auuaggcaaa      780

cuacacucca auaacaaaau agggauagaa accuuaacag aaguaaugaa aguauaucca      840

uaucuaucaa ugcaacauuu gcaaucagca gaccaaauaa aacgacauua ugauaguaaa      900

gacgcagaag gaaauaaaau accacuagau aaauucaaga aagaaggaaa agaaaaauau      960

uguccaaaaa cauacacauu cgaugacgga aaaguaauaa uuaaagccgg ugcccgggua     1020

gaagaagaaa aaguaaaacg acuguauugg gcuucuaaag aagucaauuc acaauucuuu     1080

aggguauacg gaauugauaa accucuagaa gaagguaacc cagacgacau ccuaacaaug     1140

gucauauaca auagcccgga agaauacaaa uuaaacucgg uauuauacgg guaugacaca     1200

aauaacggcg gcauguacau ugaacccgaa ggaacguucu ucacauauga aagagaagca     1260

caagaaucaa cauacacacu cgaagaacua uuuagacacg aauauacaca uuauuuacaa     1320

gggagauacg ccguacccgg acaauggggu cgaaccaaac uuuacgacaa cgacaggcua     1380

acaugguacg aagaaggggg agcagaauua uucgcaggau caacaagaac cucaggaaua     1440

cuaccuagaa aaaguauagu aucaaauaua cauaauacaa ccaggaauaa cagauauaaa     1500

uuaagugaca caguccauuc aaaauaugga gccuccuuug aguucuauaa cuacgcaugu     1560

auguucaugg auuacaugua caacaaagau augggaaucc uaaacaaacu aaacgaccua     1620

gcuaaaaaua acgauguuga cggauacgau aacuacauaa gagaccucag cucaaacuau     1680

gcacuuaacg acaaauauca agaucauaug caagaaagaa uagacaacua cgaaaaucuc     1740

acaguaccau ucguagcaga cgauuauuua guaagacacg cauacaagaa cccuaacgaa     1800

aucuauuccg aaauuagcga aguagcgaaa cuuaaagacg caaaaaguga aguaaagaaa     1860

agucaauacu ucagcacauu cacacuacga ggauccuaca caggcggcgc aagcaaaggc     1920

aaacuagaag aucaaaaagc aaugaacaaa uucauagacg auucacucaa gaaauuagau     1980

acauauagcu ggaguggaua caaaacacua acugcauauu ucacaaacua caaaguugac     2040

agcucaaaua gagucacaua ugauguagua uuccacggau aucuacccaa ugaaggugac     2100

agcaaaaacu ccuuaccaua cggaaaaauu aacgggacau acaaaggaac agaaaaagag     2160

aaaauaaaau ucucauccga agguagcuuu gaccccgaug gaaaaauugu aucauaugaa     2220

ugggacuucg gagacggaaa uaaaucaaac gaagaaaauc cugaacacag cuaugauaaa     2280

guuggcaccu auaccgugaa acuaaaagug acagaugaca aaggugaauc auccguaucc     2340

acaacgacag cagaaauuaa agacuuaagc gaaaacaaac uaccaguaau auacaugcau     2400

guaccaaaau ccggcgcauu aaaucaaaaa gucguauuuu auggaaaagg gacuuaugac     2460

cccgaugggu caaucgcagg cuaucaaugg gacuucggcg auggcucaga cuucucauca     2520

gaacagaacc caucucaugu uuacacaaag aaaggagaau acacaguaac auuacgaguc     2580

auggauucau caggucaaau gucagagaaa acaaugaaaa uaaaaauaac agauccgguu     2640

uacccaauag gaacagaaaa agaacccaac aauucaaaag aaacagcaag uggcccuaua     2700

guuccaggua uuccuguauc agguacaauc gaaaacacau cagaccagga uuacuuuuac     2760

uucgacguga uuacgccagg agaaguuaaa aucgauauua auaaauuagg auauggugga     2820

gccacguggg uaguauacga ugaaaauaau aaugcaguau cauaugccac agaugacgga     2880

caaaaucuuu cagggaaauu uaaagcugau aaaccaggaa gauauuauau acaccuuuac     2940

auguucaacg guucauacau gccuuacaga auaaauauag aaggauccgu agguagauaa     3000


<210>  1195
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  1195
augaaauggg ugacauucau cucacuauua uuucuauuca guagcgcaua uucuaugaaa       60

cgaaaaugcu uauccaaaag acuaaugcua gcaauaacaa uggcaacaau cuucaccgua      120

aauucaacau uaccaaucua cgcagccgua gauaaaaaca augcaacagc agcucgaagg      180

agaaggaaaa ggguacaaaa cgaaagcaaa agauauaccg ucagcuaccu uaaaaccuua      240

aauuacuacg acuuaguaga ucucuuagua aaaacagaaa uagaaaacuu acccgauuug      300

uuucaauauu cauccgacgc aaaagaguuc uacggaaaua aaacaagaau gagcuucaua      360

auggacgaaa uaggucggag agcuccccaa uauaccgaaa uagaucauaa aggaauacca      420

accuuaguag aaguaguaag agccggauuu uaccuuggcu uccauaacaa agaacuaaac      480

gaaauaaaca aacgauccuu caaagagcgc guaauaccaa guauacuggc cauccagaaa      540

aacccaaacu uuaaauuagg aacggaaguu caagacaaaa uaguaagugc aacagggcuc      600

cuagcaggaa acgaaacagc ucccccugaa guuguaaaua acuucacacc aauacuucaa      660

gacuguauua aaaacauaga cagauacgca uuagacgacc uuaaaagcaa agcguuauuu      720

aacguacuag cugcacccac uuaugacaua acugaauacu uaagagcaac aaaagaaaaa      780

ccagaaaaca caccuuggua uggcaaaaua gauggauuua uaaaugaacu aaagaaacug      840

gcacuauaug gcaaaaucaa cgauaauaac aguuggauaa uagacaacgg uauauaucau      900

auagcaccac uagguaaauu gcauucaaac aauaaaauug guauagaaac guuaacagag      960

gugaugaaag uauacccaua ccuaucuaug caacauuuac aaucagcgga ucaaauuaaa     1020

aggcacuaug auucaaaaga ugcggaaggu aacaaaauac cacuagacaa auucaagaaa     1080

gaaggaaaag aaaaauauug ucccaaaaca uacacauuug augaugguaa aguaauaaua     1140

aaagcagggg cucgaguaga agaagaaaaa guuaaacgac uauacugggc cucaaaagaa     1200

gucaacucuc aauuuuuccg cguauacgga aucgauaaac cauuagaaga agguaauccg     1260

gaugauauau uaaccauggu gaucuacaac ucaccagaag aauacaaacu aaauucaguc     1320

cuauauggau acgacacuaa uaauggugga auguacauag aaccagaagg cacauucuuc     1380

acauacgaaa gagaggcuca agaaucaaca uacacacuag aagaauuauu ccgacacgaa     1440

uacacacauu acuuacaagg aagauacgcg guacccggac aauggggaag aacaaaacua     1500

uacgauaaug aucgacuuac augguaugaa gaaggaggag ccgaacuauu cgcaggaucc     1560

acgcgcaccu cagggauucu uccaagaaaa ucaauaguau caaauauaca caauacaaca     1620

cgaaauaaca gauauaaauu aucagacaca guacacucca aauauggcgc aaguuucgag     1680

uucuacaauu acgcauguau guucauggau uacauguaua acaaagauau ggggaucuua     1740

aacaaacuaa acgauuuagc gaaaaacaau gacguagacg gcuaugacaa cuacauacga     1800

gacuuaucca gcaauuacgc acuuaacgau aaauaccaag aucacaugca agaaagaaua     1860

gauaacuacg aaaaucuaac agucccauuu gucgcagacg acuaccuggu gagacacgcu     1920

uacaaaaauc caaaugaaau auacucagaa auaagcgaag uagcuaaacu caaagacgcc     1980

aaaagugaag uuaagaaaag ucaauacuuu ucaacauuca cccuccgggg aucauauacc     2040

gggggagcau cuaaaggaaa auuagaagac caaaaagcca ugaauaaauu uauagaugac     2100

ucccuaaaga aacuggacac uuacuccugg aguggguaca aaacuuuaac agcuuauuuc     2160

accaacuaua aaguagacag cagcaaucga gucacauaug acgucguguu ucaugguuac     2220

uuaccaaacg aaggagacag caaaaacuca cuucccuaug guaaaauaaa cgguacauac     2280

aaaggaacag aaaaagagaa aauuaaauuc ucuucugaag gaucauuuga uccagaugga     2340

aaaaucguga guuaugaaug ggacuuugga gacggaaaca aaucuaacga agaaaaccca     2400

gaacacaguu augauaaagu uggaaccuac acaguaaaac uaaaagugac ugacgauaaa     2460

ggagaaucau cagucaguac aacuacagcc gaaauaaaag aucuaagcga aaauaaacuc     2520

cccguaauau auaugcacgu cccaaaauca ggagccuuaa aucaaaaagu ugucuuuuac     2580

gguaaaggaa cauacgaucc cgauggauca aucgcaggau aucaauggga cuuuggagau     2640

gguagcgauu ucuccagcga acaaaacccc ucacacguau auacaaagaa aggagaguau     2700

acaguaacau uaagagugau ggauagcucg ggacaaaugu cagagaaaac aaugaaaaua     2760

aaaauuacgg auccaguaua ccccauagga acagaaaaag aaccaaacaa uuccaaagaa     2820

accgcuagug guccaaucgu acccggcauu ccggugagcg guacuauaga gaacacauca     2880

gaccaagauu acuuuuacuu cgacgucauu acaccaggcg aaguaaaaau agauauaaau     2940

aaauuagguu acggaggugc aacuugggua guauaugacg agaacaacaa cgccgucuca     3000

uacgcaaccg acgacgguca aaaucuauca ggaaaauuca aagcagacaa accagguaga     3060

uacuacauuc accuauacau guucaaugga aguuacaugc cauacagaau aaacauagaa     3120

ggauccguug gaagauaa                                                   3138


<210>  1196
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  1196
augggaacau ggauacuuuu cgcaugccua cucggagcag cauucgcaau gccacuacca       60

ccacacccag gacacccagg auacauaaac uucucauacg aaguacuaac accacuaaaa      120

ugguaccaau caauaagacc accauaccca ucauacggau acgaaccaau gggaggaugg      180

uuacaccacc aaauaauacc aguacuauca caacaacacc cacccacaca cacauuacaa      240

ccacaccacc acauaccagu aguaccagca caacaaccag uaauaccaca acaaccaaug      300

augccaguac caggacaaca cuccaugaca ccaauacaac accaccaacc aaaccuacca      360

ccaccagcac aacaaccaua ccaaccccaa ccaguacaac cacaaccaca ccaaccaaug      420

caaccacaac caccaguaca cccaaugcaa ccacuaccac cacaaccacc acuaccacca      480

auguucccaa ugcaaccacu accaccaaug cucccagacc uaacacuaga agccuggcca      540

ucaacagaca aaacaaaaag agaagaagua gacuaa                                576


<210>  1197
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  1197
augccucuac cuccacaucc aggucacccu ggauauauaa auuucucuua cgaaguacuu       60

acaccucuaa aaugguauca aucuauacgu ccaccuuacc cuucauaugg auaugaaccu      120

auggguggau gguaa                                                       135


<210>  1198
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  1198
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aucaauaaga ccaccaccaa ugcuaccaga ccuaacacua      120

gaagcauggc caucaacaga caaaacaaaa agagaagaag uagacuaa                   168


<210>  1199
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  1199
auggcaguaa uggcaccaag aacacuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauacau aaacuucuca      120

uacgaaguac uaacaccacu aaaaugguac caaucaauaa gaccaccaua cccaucauac      180

ggauacgaac caaugggagg augguaa                                          207


<210>  1200
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  1200
auggcaguaa uggcaccaag aacacuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauacau aaacuucuca      120

uacgaaguac uaacaccacu aaaaugguac caaucaauaa gaccaccacc aaugcuacca      180

gaccuaacac uagaagcaug gccaucaaca gacaaaacaa aaagagaaga aguagacuaa      240


<210>  1201
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  1201
augggaacau ggauccuauu cgcuugccua guaggagcag cauucgccau gccauuacca       60

ccacacccag gacacccagg auacauaaac uucucauacg aaguacuaac accacucaaa      120

ugguaccaau caaugauaag accaccauac ucaucauacg gauacgaacc aaugggagga      180

uggcuacacc accaaauaau accaguagua ucacaacaac acccauuaac acacacacua      240

caaucacacc accacauacc aguaguacca gcacaacaac caagaguaag acaacaagca      300

cucaugccag uacccggaca acaaucaaug acaccaacac aacaccacca acccaaccua      360

ccacuaccag cacaacaacc auuccaacca caaccagucc aaccacaacc acaccaacca      420

augcaaccac aaccaccugu acaaccaaug caaccacuau uaccacaacc accacuccca      480

cccauguucc cacuaagacc acuaccacca auacuaccag accuacaccu agaagcaugg      540

ccagcaacag acaaaacaaa acaagaagaa gucgacuaa                             579


<210>  1202
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  1202
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aucaaugaua agaccaccau acucaucaua cggauacgaa      120

ccaaugggag gaugguaa                                                    138


<210>  1203
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  1203
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aucaaugaua agaccaccac caauacuacc agaccuacac      120

cuagaagcau ggccagcaac agacaaaaca aaacaagaag aaguagacua a               171


<210>  1204
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  1204
auggcaguaa uggcaccaag aacauuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacau ccaggacacc caggauauau aaauuucuca      120

uacgaaguau uaacaccacu aaaaugguau caaucaauga uaagaccacc auacagcuca      180

uacggauacg aaccaauggg aggaugguaa                                       210


<210>  1205
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  1205
auggcaguaa uggcaccaag aacacuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauacau aaacuucuca      120

uacgaaguac uaacaccacu aaaaugguau caaucaauga uaagaccacc accaauacua      180

ccagaccuac accuagaagc auggccagca acagacaaaa caaaacaaga agaaguagac      240

uaa                                                                    243


<210>  1206
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  1206
augggaaccu ggauauuauu cgcaugccua cuaggagcag cauucucaau gccacuacca       60

ccacacccag gacacccagg auacauaaac uucuccuacg aaguauuaac accacuaaaa      120

ugguaccaaa acaugauaag acaccccuac acaucauacg gauacgaacc aaugggagga      180

uggcuacacc accaaauaau acccguagua ucacaacaaa caccacaauc acacgcacua      240

caaccccacc accacauacc aaugguacca gcacaacaac caggaauacc acaacaacca      300

augaugccac uaccaggaca acacucaaug acaccaacac aacaccauca accaaaccua      360

ccacuaccag cacaacaacc auuccaacca caaccaguac aaccacaacc acaccaacca      420

cuacaacccc aaucaccaau gcaccccaua caaccacuac uaccacaacc accacuacca      480

ccaauguucu caaugcaauc acuacuaccc gaccuaccac uagaagcaug gccagcaaca      540

gacaaaacaa aacgcgaaga aguagacuaa                                       570


<210>  1207
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  1207
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aaauaugaua agacacccau acacaucaua cggauacgaa      120

ccaaugggag gaugguaa                                                    138


<210>  1208
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  1208
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aaacaugaua agacacccau cacuacuacc agaccuacca      120

cuagaagcau ggccagcaac agacaaaaca aaaagagaag aaguagacua a               171


<210>  1209
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  1209
auggcaguaa uggcaccaag aacauuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacau ccaggacacc caggauauau aaauuucuca      120

uacgaaguau uaacaccacu aaaaugguau caaaauauga uaagacaucc auauacauca      180

uacggauacg aaccaauggg aggaugguaa                                       210


<210>  1210
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  1210
auggcaguaa uggcaccaag aacacuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauacau aaacuucuca      120

uacgaaguac uaacaccacu aaaaugguac caaaacauga uaagacaccc aucacuacua      180

ccagaccuac cacuagaagc auggccagca acagacaaaa caaaaagaga agaaguagac      240

uaa                                                                    243


<210>  1211
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  1211
augggaacau ggauauuauu cgcaugccua cuaggagcag ccuucucaau gccacuacca       60

ccacacccag gacacccagg auacauaaac uucucauaca uaagacaucc auacacauca      120

uacggauaug aaccaauggg aggauggcua caccaccaaa uaauaccagu aguaucacaa      180

caaaccccac aaucacacgc acuacaacca caccaccaca uaccaauggu accagcacaa      240

caaccaggaa uaccacaaca accaaugaug ccauuaccag gacaacacuc caugacacca      300

acacaacacc accaaccaaa ccuaccacua ccagcacaac aaccauucca accacaacca      360

guacaaccac aaccacacca accacuacaa ccacaaucac caaugcaccc aauacaacca      420

cuacuacccc aaccaccacu accaccaaug uucucaaugc aaucacuacu accagaccua      480

ccacuagaag cauggccagc cacagacaaa acaaaacgag aagaaguaga cuaa            534


<210>  1212
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  1212
augggaacau ggauauucuu cgcaugcuua cuaggagcau ccuuagcaau gccacuacca       60

ccacacccag gccacccagg auacauaaac uucucauacg aaguacuaac accacuaaaa      120

ugguaccaaa acaugauaag acacccauac acaucauacg gcuacgaacc aaugggcggc      180

uggcuacacc accaaauuau accaguagua ucacaacaaa caccacaauc acacgcacua      240

caaccccacc accacauacc aaugguacca gcacaacaac ccggaauacc acaacaacca      300

augaugccac ucccaggaca acacucaaug acaccaacac aacaccacca accaaaccuc      360

ccacuaccag cacaacaacc auuccaaccc caaccaguac aaccacaacc acaccaacca      420

cuacaaccac aaucaccuau gcacccaaua caaccauuac uaccccaacc accacuacca      480

ccaauguucu caaugcaauc acuacuacca gaccuaccac uagaagcaug gccagcaaca      540

gacaaaacaa aaagagaaga agucgacuaa                                       570


<210>  1213
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  1213
augggaacau ggauacuauu cgcaugccua cuaggagcag cauucucaau gccacuacca       60

ccacacccag gacacccagg auacauaaac uucucauacg aaguacuaac accacuaaaa      120

ugguaucaaa acaugauaag acacccauca cuauuaccag accuaccacu agaagcaugg      180

ccagcaacag acaaaacaaa aagagaagaa guagauuaa                             219


<210>  1214
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  1214
augggaacau ggauacuauu cgcaugccua cuaggcgcag cauucucaau gccacuacca       60

ccacaccccg gacacccagg cuacauaaac uucucauacg aagauuuaua cuuagaagca      120

auaagaauag acagaacagc auuuguauua acaccacuaa aaugguacca aaacaugaua      180

agacacccau acacaucaua uggauacgaa cccaugggag gauggcuaca ccaccaaaua      240

aucccaguag uaucacaaca aacaccacaa ucacacgccc uacaaccaca ccaccacaua      300

ccaaugguac cagcacaaca accaggaaua ccacaacaac ccaugaugcc acuaccagga      360

caacacucaa ugacaccaac acaacaccac caacccaacc uaccacuacc agcacaacaa      420

ccauuccaac cacaaccagu acaaccacaa ccacaccaac cauuacaacc acaaucacca      480

augcacccaa uacaaccccu acuaccacaa ccaccacuac caccaauguu cucaaugcaa      540

ucacuacuac cagaccuacc acuagaagcc uggccagcaa cagacaaaac aaaaagagaa      600

gaaguagacu aa                                                          612


<210>  1215
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  1215
augggaacau ggauacuauu cgcaugccua cuaggagcag cauucucaau gccacuccca       60

ccacacccag gacacccagg auacauaaac uucucauacg aaguacuaac accacuaaaa      120

ugguaccaaa acaugauaag acacccaaca ccacaaucac acgcacucca accacaccac      180

cacauaccaa ugguaccagc acaacaaccc ggaauaccac aacaaccaau gaugccacua      240

ccaggacaac acuccaugac accaacacaa caccaccaac caaaccuccc acuaccagca      300

caacaaccau uccaaccaca accaguacaa ccacaaccac accaaccacu acaaccacaa      360

ucacccaugc acccaauaca accacuacuc ccacaaccac cacuaccacc aauguucuca      420

augcaaucac uacuaccaga ccucccacuc gaagcauggc cagcaacaga caaaacaaaa      480

agagaagaag uagacuaa                                                    498


<210>  1216
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  1216
augccacucc caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacuc       60

acaccccuaa aaugguacca aaacaugaua agacaccccu acacaucaua cggauacgaa      120

cccaugggag gauggcuaca ccaccaaaua auaccaguag ucucacaaca aacaccacaa      180

ucacacgcac uccaaccaca ccaccacauc ccaaugguac cagcacaaca accaggaaua      240

ccacaacaac caaugaugcc acuaccagga caacacucaa ugacaccaac acaacaccac      300

caaccaaacc uaccacuacc cgcccaacaa ccauuccaac cccaaccagu acaaccacaa      360

ccacaccaac cacuccaacc acaaucacca augcacccaa uacaaccacu acuaccacaa      420

ccaccacucc caccaauguu cucaaugcaa ucacuacucc cagaccuacc acuagaagca      480

uggccagcaa cagacaaaac aaaaagagaa gaaguagacu aa                         522


<210>  1217
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  1217
augccugggg uugcaagacu accguuacua uugggauuac uacuauuacc aaggccagga       60

agaccauuag auuuagcaga uuauacguau gauuuagcag aagaagacga uagugaacca      120

uuaaauuaua aagauccaug uaaagcagcc gcguuuuuag gggacauagc acuagaugaa      180

gaagaucuaa gagcauuuca aguacaacaa gcaguugacc uaagaagaca cacagcuaga      240

aaaucaucaa uuaaagccgc ugucccggga aauacgagua caccgaguug ucaaucuacu      300

aacggacagc cacaacgugg ugcaugcgga agauggagag gacgcucaag gagucggaga      360

gcggcaacaa gcagaccaga aagggucugg ccagauggag uaauaccuuu cguaauagga      420

ggaaauuuua caggaaguca aagagcagua uuccgucaag cuaugagaca uugggaaaaa      480

cauaccugug uaacguuuuu agaaagaaca gaugaagaua guuacauagu guuuacguau      540

cgaccaugcg gauguuguuc uuacguagga agacgagggg guggucccca agcaauauca      600

auagguaaaa acugcgauaa auucgggaua guaguacaug aacuagggca uguaguugga      660

uuuuggcaug aacacacacg acccgauaga gauagacaug ucucaauagu aagggaaaac      720

auacaacccg gacaagaaua uaauuucuua aaaauggaac cacaagaagu ugaaaguuua      780

ggugaaacgu augacuucga uaguauuaug cauuaugcac gaaauaccuu uaguagagga      840

auuuuucuug acacuauagu accgaaauau gaaguaaaug guguaaaacc accaauaggu      900

caaagaacaa gauuaucaaa aggagauaua gcacaagcuc gaaaacugua caaaugccca      960

gcuuguggug aaacauugca agauucaaca ggaaauuuca guagcccaga auacccaaac     1020

ggauauagug cgcauaugca uugcgucugg aggauuagug uaacaccagg ugagaaaaua     1080

auacuaaauu uuacgaguuu agacuuauau cgaagcagau uauguuggua ugacuauguu     1140

gaaguuagag auggauuuug gagaaaagca ccauuaagag gaagauuuug uggaucaaaa     1200

cuaccagaac caauaguaag uacagauagu aggcuuuggg uagaguucag aagcucgagu     1260

aauuggguag gcaaaggauu cuuugcaguc uaugaagcca uauguggagg ggauguuaag     1320

aaagacuaug gacacauaca aucaccuaau uauccggacg auuaccgacc aagcaaaguu     1380

uguauuuggc ggauucaagu aagcgaaggu uuccacguag gacuuacauu ccaaucuuuu     1440

gaaauugaac gccaugauag uugcgcauac gacuaucuag aaguaagaga uggucauagc     1500

gaaaguucaa cacuaauugg aagauacugc ggauaugaaa aaccugacga uauaaaauca     1560

acaagcaguc gauuauggcu aaaauuugug agugacggaa gcauaaauaa agcuggcuuc     1620

gcuguaaacu uuuucaaaga aguagaugaa uguaguagac caaauagggg cggaugugaa     1680

caacguuguu uaaauacuuu aggcucguau aaaugcagcu gugaucccgg auaugaacuc     1740

gcaccagaua aaagaagaug ugaagcagca uguggaggau uuuugacaaa acuuaauggu     1800

uccauaacca guccagggug gccaaaagaa uauccgccaa auaaaaauug cauuuggcag     1860

cuaguagcuc caacucaaua ccguaucagu uuacaauucg acuucuuuga aacagaaggc     1920

aaugacguau gcaaauacga uuuuguagaa guuagaucug ggcuaaccgc ugacaguaaa     1980

uuacauggaa aauuuugugg cucagaaaaa ccagaaguaa ucacaucaca auacaauaac     2040

augagagucg aguuuaaaag cgauaacaca guuaguaaga aagguuuuaa agcccauuuc     2100

uuuagugaua aagaugaaug cucaaaagau aauggagggu gucaacaaga uugcguaaau     2160

acauuuggaa gcuacgaaug ccaauguaga uccggauuug uacuccauga uaauaaacac     2220

gauuguaaag aagcaggaug ugaccacaaa guaaccucua caucggggac uaucacgagu     2280

ccaaacuggc cagauaaaua cccuucaaag aaagaaugca cuugggcgau caguucuacu     2340

ccaggacaua ggguuaaauu aacauuuaug gaaauggaca uagaaucaca accugaaugu     2400

gcuuaugacc auuuagaagu uuuugaugga agagaugcua aagcgccugu uuuaggucgg     2460

uuuugcggaa guaaaaagcc ugaaccuguc uuagccacug gcucaaggau guuuuuaagg     2520

uuuuauucag acaacucagu ccaaagaaaa ggauuucaag caagucaugc gacagaaugc     2580

ggaggccaag uacgagcaga uguaaaaaca aaagaucuuu auucucaugc acaauuuggu     2640

gauaauaauu auccuggagg aguugauugu gaguggguaa uaguagcaga agaagguuau     2700

ggaguugaau uaguauuuca aacguuugaa guagaagaag aaaccgauug cgguuaugac     2760

uacauggaac uauucgaugg uuaugauuca acagcuccua gauuaggaag auauuguggg     2820

ucaggcccgc cagaggaagu auauagugca ggagauagcg uucuaguaaa auuucacagc     2880

gacgacacaa uaaccaagaa aggauuccau cuacgcuaua caucaacuaa auuccaagau     2940

acacuacaua gcagaaaaua a                                               2961


<210>  1218
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  1218
auggucgcag gaacaagaug ucuacuagca cuauuacuuc cacaaguucu acuaggagga       60

gcagcuggau uaguaccaga auuaggaaga agaaaauuug cggcagcauc aucuggaaga      120

cccaguucac aaccaucaga cgaaguauua ucagaauuug aacuuagacu acuuagcaug      180

uucggauuaa aacaacgucc cacaccaucu agagaugcag uaguaccacc cuauaugcuu      240

gaccuauaca gacgucacag cggccaacca ggaucaccag caccagacca uagacuagaa      300

agagccgcau caagagcaaa cacaguaaga ucauuccacc augaagaaag cuuagaagaa      360

uuaccagaaa caucagguaa aacuacaaga agguuuuucu uuaacuuaag cucuauacca      420

acagaagaau uuauaacauc agcagaauua caaguauuca gagaacaaau gcaagacgca      480

cuaggcaaua auagcagcuu ucaccacaga auaaauauau augaaauuau aaaaccagca      540

acagcaaacu caaaauuucc aguaacaaga cuauuagaca cacgacuagu aaaucaaaau      600

gcaucaagau gggaauccuu cgacguaaca ccagcaguaa ugagauggac agcacaagga      660

cacgcaaacc auggauuugu aguagaagua gcucacuuag aagaaaaaca aggaguaagu      720

aaacgucaug uaagaauuag cagaaguuua caucaagacg aacauuccug gucucaaauu      780

agaccacuac uaguaacauu cggacaugac ggaaaaggac acccacuaca caaaagagaa      840

aaacgacaag caaaacauaa acaacguaaa agauuaaaau ccucauguaa aagacaucca      900

uuauacguag auuucucaga cguaggaugg aacgacugga uaguagcacc acccggauac      960

cacgcuuucu auugccaugg agaaugccca uucccacuug cagaccaucu aaacagcaca     1020

aaucacgcca uuguacaaac auuaguaaac agcguaaacu ccaaaauacc aaaagcaugc     1080

ugcguuccaa cagaauuaag cgcaauauca auguuauacu uagacgaaaa ugaaaaagua     1140

guacuaaaaa auuaccaaga caugguagua gaaggcugug gaugccgcua a              1191


<210>  1219
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  1219
augauaccag gaaauagaau gcuuauggua guauuacuau gccaaguauu acuaggaggu       60

gcaucccaug ccucauuaau accagaaacc ggcaaaaaaa aaguagcuga aauacaagga      120

caugcaggag gaagaagauc cggacaauca cacgagcuac uaagagacuu ugaagcuaca      180

uuauuacaaa uguuuggauu acgaagaaga ccacaaccuu caaaaucagc ugucauucca      240

gauuauauga gagacuuaua uagauuacaa ucuggugaag aagaagaaga acaaauccac      300

ucaacuggac uggaauaucc agaaagacca gcuucaagag cuaauacugu ucguucauuu      360

caucacgaag aacauuuaga aaacauacca ggaacaagcg aaaauagugc auuuagauuc      420

uuauucaacc uauccagcau uccagaaaac gaaguaauau caagugcaga auuaagauua      480

uuucgugaac aaguagauca aggaccagac ugggaaagag gauuucacag aauuaacaua      540

uaugaaguua ugaaaccacc ugcagaaguc guaccagguc accuaauaac aagauuauua      600

gauacaagac uaguacauca uaacgucaca agaugggaaa cuuuugacgu aucaccagca      660

guauuacgau ggacacgaga aaaacaacca aauuacgguc uagcaauaga aguaacacac      720

cuacaucaaa caagaaccca ccaaggacaa cauguacgaa uaucaagauc auuaccacaa      780

ggaagcggaa acugggcaca auuaagacca cuacuaguua cuuuuggaca cgauggaaga      840

ggacacgcac uaacacggag aagaagagca aaacguucac caaaacacca uucucaaaga      900

gcaagaaaaa aaaauaaaaa cugcagacga cauagcuuau auguagauuu cucagaugua      960

ggguggaaug acuggauagu agcaccucca ggauaccaag cauuuuacug ucacggugac     1020

uguccauuuc ccuuagccga ucacuuaaac ucaacaaauc augcaauagu acaaacacua     1080

guaaacagug uaaacucaag uauaccuaaa gcaugcugcg uaccaacaga acuaucagca     1140

auuucaaugu uauaccuaga cgaauaugac aaaguuguau uaaaaaauua ucaagaaaug     1200

guuguagaag gauguggaug uagauaa                                         1227


<210>  1220
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  1220
augccaggac uagguagaag ggcccaaugg cuauguuggu gguggggucu auuauguuca       60

uguuguggac ccccuccucu aagaccacca uuaccagcug cugcagcagc agcagccggc      120

gggcaauuac uaggagaugg aggcucgcca ggaagaacag aacaaccacc accaucacca      180

caaucaucau cagguuuccu auacagacga cuuaaaacac aagaaaaacg agaaaugcaa      240

aaagaaauau uaucuguuuu aggucuacca cauagaccua gaccacuaca uggccuacaa      300

caaccucaac cuccagcccu ucgccaacaa gaagaacaac aacaacaaca acaauuacca      360

agaggugagc caccacccgg uagauuaaaa ucagcuccuu uauucauguu agauuuauac      420

aacgcccuau ccgccgauaa ugaugaagau ggagcaucag aaggcgagag gcaacaauca      480

uggccgcaug aagcagcuuc aucaucacaa cgccgacaac caccuccugg ugcugcacau      540

ccauuaaauc guaaaagccu acuugcacca ggaucaggau cuggaggagc cucaccacua      600

acaagcgcac aagauucagc auuucuaaau gacgcugaua uggucaugag uuuuguaaau      660

cuaguagaau acgauaaaga guucucucca agacaaagac aucauaaaga auuuaaauuu      720

aaucuaucuc aaaucccaga aggagaagua guaacagcgg cagaauuuag aauauauaaa      780

gauuguguaa ugggaucauu caaaaaucaa acuuuucuaa uuucaauaua ccaaguauua      840

caagaacauc aacaucgcga cucagaccuc uuuuuacucg acacccgagu uguuugggca      900

uccgaagaag gcuggcuaga auuugauauu acagcaacau caaauuuaug gguaguaacc      960

ccucaacaua acauggguuu acaauuaagu guaguaacaa gagacggagu ucacguccac     1020

ccaagagcug caggauuagu aggaagagau ggaccauaug acaaacaacc auucaugguu     1080

gcauucuuua aaguuaguga aguucaugua cgaacaacaa gaucagcaag uucaagaaga     1140

agacaacaau cuagaaaccg aaguacacaa ucacaagaug uugcacgagu aucaucugcc     1200

agugacuaua auucaucaga auuaaaaaca gcauguagaa aacacgaauu auacguauca     1260

uuucaagauu uagguuggca agacuggaua auagcaccaa aaggauacgc agcaaauuau     1320

ugugacggcg aauguucauu uccuuuaaau gcacauauga augcaacaaa ccaugcaaua     1380

guccaaacau uaguccacuu aaugaaucca gaauacguac caaaaccuug uugugcccca     1440

acaaaauuaa augcaaucuc aguacuauac uucgaugaua auucaaaugu aauauuaaag     1500

aaauaccgaa auaugguagu aagagcuugc ggcugucacu aa                        1542


<210>  1221
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  1221
augcauguca gaucacuuag agcagcagcc ccacauucuu ucguagcauu augggcacca       60

uuauucuuau uaagaagcgc acuagcagac uuuucauuag acaaugaagu acauaguagc      120

uuuauacaua gacgccuaag aucacaagaa agacgagaaa ugcaaagaga aauccuauca      180

auauuaggau uaccacauag accaagaccu caucuacaag gaaaacacaa cuccgcucca      240

auguucaugu uagaccuaua uaacgcaaug gcugucgaag aaggaggagg uccaggagga      300

caagguuuua guuaucccua caaagcagua uuuagcacac aaggcccacc acucgcaagc      360

uuacaagauu cccauuuccu aacagaugcc gauaugguua ugaguuucgu uaaucuugua      420

gaacacgaua aagaauucuu ccacccuaga uaucaccauc gagaguucag auucgaucuu      480

ucaaaaauac cagaaggaga agccguuacc gcagcagaau uuagaauaua uaaagauuac      540

auccgcgaac gauuugacaa ugaaacauuc agaauaucag uauaucaagu acuacaagaa      600

caucuaggga gagaaucaga ucuauuuuua uuagacucua gaacacuaug ggcaucagaa      660

gaaggauggu uaguuuucga uauaacagcc acaagcaauc acuggguagu aaacccuaga      720

cacaacuuag gauuacaauu aagcguagaa acacucgacg gccaaaguau aaaccccaaa      780

cuagcaggac uaauaggacg acacggccca caaaacaaac aaccauuuau ggucgccuuu      840

uucaaagcua cagaaguaca uuuccgauca auacgaucua caggauccaa acaaagauca      900

caaaacagau cuaaaacacc aaaaaaucaa gaagcauuaa gaauggccaa uguagcagaa      960

aauagcucau cagaucaacg acaagcaugc aaaaaacaug aacuauacgu gaguuucaga     1020

gaucucggau ggcaagauug gauaauagca ccagaaggau augcagccua uuauugugaa     1080

ggugaaugug cauuuccacu aaauucuuac augaaugcaa ccaaucacgc aauaguucaa     1140

acacuaguac acuuuauaaa cccagaaaca guaccaaaac cuuguugcgc accaacacaa     1200

uuaaacgcaa ucucaguauu auacuucgau gauaguucua acguaauauu aaaaaaauac     1260

agaaacaugg uagucagagc augcgguugu cacuaa                               1296


<210>  1222
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  1222
augaaagcau cagcagcacu acuaugccua cuacuaacag cagcagcauu cucaccacaa       60

ggacuagcac aaccaguagg aauaaacaca ucaacaacau gcugcuacag auucauaaac      120

aaaaaaauac caaaacaaag acuagaauca uacagaagaa caacaucauc acacugccca      180

agagaagcag uaauauucaa aacaaaacua gacaaagaaa uaugcgcaga cccaacacaa      240

aaauggguac aagacuucau gaaacaccua gacaaaaaaa cacaaacacc aaaacuauaa      300


<210>  1223
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  1223
augcuacuca cguugauaau auuauuacca guaguaucaa aauucucuuu uguuagccua       60

agugccccac aacauugguc uuguccagaa gggacguuag ccgggaaugg aaacaguaca      120

ugugugggac cugccccauu uuuaauauuu ucacacggaa auuccaucuu uagaaucgau      180

acugaaggga caaauuauga acaauuaguu guagaugccg guguaucagu aaucauggac      240

uuccauuaua augaaaaacg gauuuacugg guugaucucg aaagacaacu acuucaaaga      300

guguuuuuaa augggaguag gcaagaaaga gucuguaaua uugagaaaaa uguaucagga      360

auggcuauaa auuggauaaa cgaagaggua auauggucua aucaacaaga agguauuaua      420

acugugacug auaugaaagg aaauaacuca cauauccucc uaucugcucu aaaauauccu      480

gcuaacgugg caguugaucc agucgaacga uuuaucuuuu ggucaucaga ggucgcagga      540

ucgcuauaua gagcagacuu agauggugua ggaguaaaag cauuacuaga aaccagcgag      600

aaaauaacug caguaaguuu agauguacuc gacaaaagau uauucuggau acaauacaau      660

agagaaggau caaauucacu aauauguucu ugugacuaug auggcggaag cguccacaua      720

ucuaaacacc ccacacaaca uaauuuauuu gcgaugaguu uauuugguga uagaauauuu      780

uauaguacgu ggaaaaugaa aaccauaugg auagcuaaua aacauacagg aaaagacaug      840

guccgaauaa accuacacuc auccuuugua ccucuagggg aauugaaagu aguacaucca      900

cuagcacaac caaaagcgga agacgacaca ugggaaccgg aacaaaaacu cuguaaacuc      960

agaaagggua auuguucgag uacuguaugu ggacaagauc uacaaagcca uuuauguaug     1020

ugcgcagaag gauaugcuuu aucaagagau cgaaaauauu gcgaagaugu caaugagugu     1080

gcauuuugga aucauggaug uacccuuggc ugcaaaaaua ccccaggcuc auauuauugc     1140

acuuguccag uaggauuugu auuguuaccu gauggaaagc gaugucauca acuuguaagu     1200

uguccacgaa auguuaguga auguucacau gauugcgugu uaacaucaga aggcccauua     1260

ugcuucugcc cagaaggauc aguguuagaa agagauggca aaacuugcag uggaugcagu     1320

agcccagaca augguggaug uagucaauua uguguuccgu uauccccagu gucgugggaa     1380

ugugacuguu uuccaggaua ugauuuacag cuagacgaaa aaucuugcgc agcaagcggu     1440

ccacaacccu uuuuacuauu ugcaaauucc caagacauuc gucacaugca uuuugauggu     1500

acugauuaug guacauuauu aucacaacaa auggguaugg uauaugcauu agaccaugau     1560

ccugucgaaa acaaaauaua uuucgcucau acagccuuaa aguggaucga acgcgcuaac     1620

auggauggaa gucaaagaga aaggcucauu gaagaaggag ucgauguacc cgaaggcuua     1680

gcaguagacu ggauaggccg ccgauuuuau uggacagaua gagguaaaag ucuuauagga     1740

cguucagacu uaaauggaaa aagaaguaaa auuauaacaa aagaaaacau aucacaaccu     1800

aggggaauag caguacaucc aauggcaaaa cgccucuuuu ggacagauac aggcauaaau     1860

ccuagaauug aaaguucuag cuuacaggga cuaggccggc uaguaauugc cucaucagac     1920

cuaauauggc caagugggau aaccauagau uuucucacgg acaaauugua uuggugcgau     1980

gcaaaacagu caguaauaga aauggcuaau cucgaugguu caaagagaag gagauuaaca     2040

cagaacgaug uuggucaccc auucgcagua gcaguauucg aggauuacgu cugguuuucg     2100

gauugggcaa ugccaagugu aaugagagua aacaaaagaa cagguaaaga uagaguacga     2160

uuacaaggau ccauguuaaa gcccuccuca uuaguagucg uucauccauu ggcuaaacca     2220

ggagccgacc caugcuuaua ccaaaauggu gguugugaac acauuuguaa gaaaagauua     2280

ggaacagccu gguguucaug cagagaaggc uucaugaaag caucagaugg aaaaacaugc     2340

cuagcauuag auggacacca acuacuagca ggaggagaag uugaccucaa aaaccaagua     2400

acgcccuuag auauauuaag uaaaacucga guuagugagg acaacauaac agaaagucaa     2460

cacauguuag uggcugaaau aaugguaagu gaucaagacg auugugcacc aguaggaugu     2520

ucaauguaug cacgcuguau cucagaaggc gaagaugcaa cuugccaaug ccuaaaaggc     2580

uucgcgggcg auggaaaacu auguucagac auagaugaau gugaaauggg uguuccugua     2640

ugucccccag cguccucaaa augcauaaau accgaaggcg gcuauguaug ucguuguuca     2700

gaaggguacc aaggugaugg aauccauugu uuagauauag acgaauguca auuaggcgaa     2760

cauaguugug gugagaacgc uucuugcacc aacacagaag gagguuacac auguaugugc     2820

gcagggaggc uaagugagcc aggauuaauu uguccagaua guacaccacc uccccaccua     2880

agagaggaug aucaucauua cucaguaaga aauucagaua gugaaugucc auuaucucac     2940

gaugguuacu gccuacauga cgguguaugc auguauauag aagccuuaga uaaauaugcu     3000

uguaacugug uagucggcua cauaggagaa aggugucaau auagggaccu aaaauggugg     3060

gaauuacgac augcuggcca ugggcaacaa caaaaaguaa uaguuguagc agucuguguc     3120

guaguucuag uaaugcuccu cuuacuaucc cuauggggug cucauuauua ccgaacgcaa     3180

aaacuucuga guaaaaaucc uaaaaaucca uacgaagaau caucaagaga uguacgauca     3240

aggagaccag ccgauacaga agaugggaug ucgucuugcc cacagccaug guucguugua     3300

auaaaagaac accaagauuu gaaaaacgga ggucaaccug ucgcaggaga ggauggacaa     3360

gcugcagaug guaguaugca acccacaagu uggagacaag aaccccaauu augcggaaug     3420

ggaacggaac aagggugcug gauuccagua ucgagcgaca aagggucuug cccccaagua     3480

auggaaagau cguuccauau gcccucauac ggaacgcaaa cuuuagaagg aggaguagag     3540

aaaccacauu ccuuacuaag cgcaaaucca uuauggcaac aacgagcuuu agauccacca     3600

caucaaaugg aauugacaca auaa                                            3624


<210>  1224
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  1224
augacagcag gaagaagaau ggaaaugcua ugugcaggaa gaguaccagc acuauuacua       60

ugucuaggau uccaucuauu acaagcagua uuaaguacaa caguaauacc aagcuguaua      120

ccaggagaaa gcucagacaa uugcacagca uuaguacaaa cagaagacaa uccaagagua      180

gcacaaguaa gcauaacaaa augcucaagu gauaugaaug gauauugcuu acacggacaa      240

uguauauauc uaguagacau gagccaaaac uauugcagau gcgaaguagg auacacggga      300

guaagaugug aacacuucuu ucuaacagua caucaaccac uaucaaaaga auacguagca      360

uuaacaguaa uauuaauaau acuauuucua auaacaguag uaggaagcac auacuauuuc      420

uguagauggu acagaaacag aaaaucaaaa gaaccaaaaa aagaauauga aagaguaaca      480

ucaggagauc cagaacuacc acaaguauaa                                       510


<210>  1225
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  1225
auggcagaag gagaaauaac aacauucaca gcacuaacag aaaaauucaa ccuaccacca       60

ggaaacuaca aaaaaccaaa acuacuauac ugcucaaacg gaggacacuu cuuaagaaua      120

cuaccagacg gaaccguaga cggaacaaga gacagaucag accaacacau acaacuacaa      180

uuaucagcag aaucaguagg agaaguauac auaaaaucca cagaaacagg acaauacuua      240

gcaauggaca cagacggacu acuauacgga ucacaaacac caaacgaaga augccuauuc      300

cuagaaagac uagaagaaaa ccacuacaac acauacauau caaaaaaaca cgcagaaaaa      360

aacugguucg uaggacuaaa aaaaaacgga ucaugcaaaa gaggaccaag aacacacuac      420

ggacaaaaag caauacuauu ccuaccccua ccaguauccu cagacuaa                   468


<210>  1226
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  1226
augguagggg ugggaggagg agacguagaa gacguaacac caagaccagg aggaugucaa       60

auaaguggaa gaggagcaag agguuguaau ggaauaccag gagcggcagc augggaagca      120

gcauuaccga gaagaagacc gagaagacac ccaaguguaa auccuagauc aagagcagcu      180

ggaagcccaa gaacacgagg aagaagaaca gaagaaaggc cuaguggaag uagauuaggg      240

gacagaggaa gaggaagagc auugccagga ggaagacuag gcggaagagg aagaggaaga      300

gcaccagaaa gaguaggagg uagaggaaga ggaagaggaa cagcagcacc aagagcagca      360

ccagcagcaa ggggaaguag accaggacca gcgggaacaa uggcagcagg aaguauaaca      420

acacuuccag cauugccaga agauggagga aguggcgcau uuccgccagg acauuuuaaa      480

gauccaaaga gauuauacug uaaaaaugga gguuuuuuuu uaagaauaca uccagaugga      540

agaguagaug gaguaagaga aaaaagugau ccacauauaa aauuacaauu acaagcagaa      600

gaaagaggag uaguaaguau aaaaggagua ugugcaaaca gauauuuagc aaugaaagaa      660

gauggaagau uacuagcaag uaaaugugua acagaugaau guuuuuucuu ugaaagauua      720

gaaaguaaua auuauaauac guaccgaagu agaaaauaua caaguuggua uguagcguua      780

aaaagaacag gacaauauaa auuaggaagc aaaacaggac cgggacaaaa agcaauauua      840

uuuuuaccua ugagugcgaa aaguuaa                                          867


<210>  1227
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  1227
augcacaaau ggauacuaac auggauacua ccaacacuac uauacagaag cugcuuccac       60

auaauaugcu uaguaggaac aauaagccua gcauguaacg auaugacacc agaacaaaug      120

gcaacaaaug uaaacugcag cucacccgaa agacacacaa gaucauacga cuacauggaa      180

ggcggagaca uaagaguaag aagacuauuc ugcagaacac aaugguacuu acgaauagac      240

aaaagaggaa aaguaaaagg aacacaagaa augaaaaaca acuacaacau aauggaaaua      300

agaacaguag caguaggaau aguagcaaua aaaggaguag aaucagaauu cuaccuagca      360

augaacaaag aaggaaaacu auacgcaaaa aaagaaugca acgaagacug caacuucaaa      420

gaauuaauac uagaaaacca cuauaacaca uacgcaagcg caaaauggac acacaacgga      480

ggagaaaugu ucgucgcacu aaaccaaaaa ggaauaccag uaagaggaaa aaaaacaaaa      540

aaagaacaaa aaacagcaca cuuccuacca auggcaauaa cauaa                      585


<210>  1228
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  1228
augaaacuac uaccaagcgu aguacuaaaa cuauucuuag cagcaguacu aagcgcacua       60

guaacaggag aaagccucga aagacuacga agaggccuag ccgcagguac aucaaaccca      120

gacccaccaa caguaucaac agaccaauua cuaccacuag gaggaggaag agacagaaaa      180

guaagagacc uucaagaagc agaccuagau cuacuaagag uuacauuauc aucaaaacca      240

caagcacuag caacaccaaa caaagaagaa cacggaaaaa gaaaaaaaaa aggaaaagga      300

cuaggcaaaa aaagagaccc augcuuaaga aaauacaaag acuucugcau acacggagaa      360

ugcaaauacg uaaaagaacu aagagcacca ucaugcauau gccacccagg auaucacgga      420

gaaagaugcc acggauuaag ccuaccagua gaaaauagac uauacacaua cgaccacaca      480

acaauacuag caguaguagc aguaguacua ucaucaguau gucuacuagu aauaguagga      540

cuauuaaugu ucagauacca cagaagaggc ggauacgacg uagaaaacga agaaaaagua      600

aaacuaggaa ugacaaauuc acacuaa                                          627


<210>  1229
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  1229
auguggguua caaaacuauu acccgccuua cuauuacagc augucuuacu acaucuauua       60

cuauuaccca uagcuauacc auaugcugaa ggccaacgua aaagaagaaa uacaauucau      120

gaauuuaaaa aaucagcuaa aacaacauua auaaaaauag acccagcuuu gaaaauaaaa      180

acaaaaaaag uaaacaccgc agaucaaugu gcaaaucgau guacacgaaa caaaggauua      240

cccuuuacau guaaagcauu uguauuugau aaagccagaa aacaaugcuu gugguuuccu      300

uucaacucaa ugucaucagg aguaaaaaaa gaauuuggcc acgaauucga ucuauaugaa      360

aauaaagauu auauaagaaa uuguauaaua ggaaaaggac gaucauauaa aggaacagua      420

aguauaacaa aaagcggaau aaaaugucaa ccguggucca guaugauacc acaugaacau      480

ucauuuuuac caucaucaua ccgagguaaa gacuuacaag aaaauuacug cagaaaucca      540

cgaggagaag aaggaggacc auggugcuuc acaucaaauc cagaaguucg auaugaagua      600

ugugacauuc cucaauguuc agaaguagaa ugcaugacuu guaauggaga aucuuauaga      660

gguuuaaugg accauacaga aaguggaaaa auaugccaac gaugggauca ccaaacacca      720

cauagacaca aauuccuacc agaaagauac ccagacaaag gauuugauga uaacuacugu      780

aggaacccgg auggacaacc aaggccaugg ugcuauacau uagauccaca uaccagaugg      840

gaauauugug caauaaaaac uugugcagau aauacaauga augacaccga uguaccacuu      900

gaaaccacag aauguauaca aggucaagga gaaggauauc gaggaacagu aaauacaaua      960

uggaauggaa uaccguguca acgaugggau agucaauacc cccaugaaca ugacaugaca     1020

ccagaaaauu uuaaaugcaa agaucuaagg gaaaauuauu guaggaaucc agauggauca     1080

gaaucaccuu gguguuucac cacagaucca aauauacgcg uuggauauug uucacaaaua     1140

ccaaauugcg acaugaguca cggacaggau ugcuauagag guaauggaaa aaauuauaug     1200

ggaaaccuau cacaaacaag aucaggucua acaugcucaa ugugggacaa aaacauggaa     1260

gauuuacaua ggcacaucuu cugggaacca gaugcaagca aauuaaauga aaauuauugu     1320

cgaaauccag augacgacgc acauggacca ugguguuaca caggaaaccc acuaauacca     1380

ugggacuauu gccccauauc aagaugcgaa ggagauacua cacccacuau aguaaaucua     1440

gaucacccug uaauaucaug ugcaaagacc aaacaacuca ggguaguaaa cggcauacca     1500

acucgaacca auauuggaug gaugguuuca cuaagauacc gcaacaagca uauaugcgga     1560

ggaagccuaa uuaaagaauc auggguauug acagcaagac aauguuuccc aagccgagac     1620

cuuaaagauu augaagcaug guuaggaaua cacgacguac auggcagagg agaugaaaaa     1680

ugcaaacaag uacuuaacgu uucucaauua gucuacggac cagaaggauc cgacuuagua     1740

cuaaugaaau uagcaagacc agcaguucua gaugauuuug uaucuacaau agaucuacca     1800

aacuacggau guacaauacc ugaaaaaaca agcugcagug uauacggaug ggguuauacu     1860

ggccuuauaa auuaugacgg acuccuaagg guagcucauu uauauauaau gggaaaugaa     1920

aaaugcuccc aacaucaucg uggaaaaguu acacuaaaug aaucagaaau augcgcaggu     1980

gcagaaaaaa uagguucagg accaugugag ggagauuaug guggaccauu aguuugugaa     2040

caacauaaaa ugcgaauggu ccuaggagua auuguaccag gaagaggaug cgcaauaccu     2100

aauagacccg gaauuuucgu cagaguagca uacuaugcua aauggauaca uaaaauaaua     2160

cuaacguaua aagugccuca aucauaa                                         2187


<210>  1230
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  1230
auggcaaaag cagcagccau aggaauagau cuugguacaa cauauucaug cguaggcgua       60

uuucaacaug gaaaaguaga aauaauagca aacgaccaag gcaaccgaac aacaccaucc      120

uacguggcuu ucacagacac agaaagacua auuggcgaug cagcuaaaaa ucaaguugca      180

uuaaauccac aaaacacagu auuugacgca aaaagacuca uaggaagaaa auuuggggau      240

ccuguagucc aaagcgauau gaaacacugg cccuuucaag uaauaaacga cggcgacaaa      300

ccaaagguac agguaaguua uaagggagaa acaaaagcau uuuaccccga agaaaucagc      360

agcaugguau uaacuaaaau gaaagaaaua gccgaggcau auuuaggaua uccaguuaca      420

aacgcaguca uaacuguacc agcauacuuu aaugauucac aaaggcaagc aacaaaagau      480

gcaggaguaa uagcuggauu aaacguauua agaauaauaa acgaaccaac agcagcagca      540

auagcguaug guuuagaccg aacaggcaaa ggagagagaa acguacuaau cuuugaucua      600

ggaggaggaa cauucgaugu aucaauauua acaaucgaug acggaauauu cgaaguuaaa      660

gcaacugcag gagacacaca cuuaggagga gaagauuuug auaacagauu aguaaaccac      720

uuuguagaag aauuuaaacg aaaacauaag aaagacauuu cacaaaauaa aagggcugua      780

agaagacuaa gaacagcuug cgaaagagcu aaaagaacac uaagcagcuc aacacaagca      840

agucuagaaa uagacaguuu auuugaagga aucgauuucu acacaucaau aacaagagca      900

cgauuugaag aacuauguag ugaccuauuu agaagcacuc uagagccugu cgaaaaagca      960

uuaagagaug cuaaauuaga caaagcacaa auacacgauc uaguucuagu aggaggauca     1020

acucgaaucc ccaaaguaca aaaacuauua caagauuucu ucaaugguag agaccucaau     1080

aaaaguauua auccagauga agcagucgca uauggugcug caguacaggc cgcaauuuua     1140

augggggaua aauccgaaaa cguccaagau cuauuauuau uagacguagc accauuauca     1200

cuagguuuag aaacagcugg agggguaaug acugcauuaa uaaaaaggaa caguacaaua     1260

ccgacaaaac aaacacaaau auuuacaaca uacucagaua aucaaccagg aguuuuaauu     1320

caaguauacg agggagaacg cgcaaugaca aaagacaaca aucucuuagg ccgguuugaa     1380

cuaucaggua uaccuccagc cccuagaggu guuccacaaa uagaaguaac auuugauauu     1440

gacgcuaaug guauccuaaa cgucacagca acugacaaau caaccggaaa agcaaauaaa     1500

aucacaauaa caaaugauaa gggaagacuu aguaaagaag aaaucgaaag aaugguacaa     1560

gaggcagaaa aauauaaagc ggaagacgaa guacaaagag aaagaguaag ugcuaaaaac     1620

gcgcuugaau ccuaugcauu caauaugaaa ucagcagucg aggacgaagg auuaaaagga     1680

aaaauaagug aagcagacaa aaagaaaguu uuagauaaau gccaagaagu uauuucaugg     1740

uuagaugcaa auacauuagc agaaaaagac gaguucgaac auaaaaggaa agaacuagaa     1800

caaguaugua auccuauaau aagcggauua uaccaaggug cgggaggucc aggacccggu     1860

gguuucggug cucaaggacc uaaaggcggc aguggaagug gaccaacuau agaagaagua     1920

gauuaa                                                                1926


<210>  1231
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  1231
auggcuaaag cagcagcaau cggaaucgau uuagggacaa cauacagcug uguaggagua       60

uuccaacacg gaaaaguuga aauaauagca aaugaucagg gaaacaggac aacuccuagc      120

uauguugcau uuaccgauac cgaacgucuc auuggagaug cggcaaaaaa ucagguagca      180

uuaaaccccc aaaacacagu auuugacgcu aaaagauuaa uaggacgaaa auucggagau      240

ccgguuguac aaagcgacau gaaacacugg ccauuucaag uaauaaauga uggagacaaa      300

ccaaaagucc aagucucuua caaaggagaa acaaaagcau ucuacccaga agaaauauca      360

aguauggucu uaaccaaaau gaaagaaaua gcagaagcau acuuagggua cccaguaaca      420

aaugcaguaa uaacaguucc cgcauauuuu aacgauagcc aaagacaagc uacuaaagac      480

gcaggaguaa ucgcaggauu aaauguacuu agaauuauaa augagccaac ugcagcagca      540

auugcauaug gauuggacag gacuggaaaa ggagaaagaa acguauuaau auuugaccua      600

ggaggaggca cauuugacgu aucaauauua accauagacg acggaauauu cgagguaaaa      660

gcaacagcag gagacaccca uuuaggagga gaagauuucg auaaucgauu aguaaaucau      720

uuuguagaag aauuuaaaag aaaacauaaa aaagauauau cacaaaauaa aagagcaguu      780

agacgauuac gaacagcuug cgaaagagca aaaagaaccc uaaguucuag cacacaagcu      840

agccuugaaa uugauucccu auuugaaggc auagauuucu auacaagcau cacucgagca      900

agauuugaag aauuaugcag ugacuuauuu agaucaacuc uagaaccugu agaaaaagcg      960

cuuagagacg ccaaauuaga uaaagcacaa auccaugauu uagucuuagu aggaggauca     1020

accagaauac ccaaaguaca aaaacuauua caagacuucu ucaacggaag agaucuaaau     1080

aaaucaauaa auccugacga ggcaguugcc uacggagccg cgguacaagc agcaauacua     1140

augggagaca aaagcgaaaa cguacaagau cuauuacuuc uagauguagc accucuaagu     1200

uuaggauuag aaacagcagg aggaguaaug accgcacuaa uaaaaaggaa uucaacgaua     1260

ccaacaaaac aaacucaaau uuucacaaca uacucagaca aucaaccugg aguacuaaua     1320

caaguauacg aaggagagag agcaaugaca aaagauaaca aucuauuggg aagauucgaa     1380

cuaucaggaa uacccccggc gccacgagga guaccgcaaa uugaaguaac uuuugauaua     1440

gaugccaaug gaauauuaaa uguaaccgca accgauaaaa gcacuggaaa agcaaauaaa     1500

auaacaauaa caaaugacaa aggaagacua ucaaaagaag aaauagaacg aaugguccaa     1560

gaagcagaaa aauacaaagc agaagacgaa guacaacgag aacgaguuuc agccaaaaau     1620

gcauuagaau cauacgcauu uaacaugaaa agugcaguag aagacgaagg acuaaaagga     1680

aaaaucucag aagcagauaa aaaaaaagua cuggauaaau gucaagaagu cauaaguugg     1740

uuagacgcaa auacauuagc agaaaaagac gaauucgaac acaaaagaaa agagcuagaa     1800

caagucugua acccuauaau aaguggacua uaccaaggag cgggaggacc aggaccagga     1860

gguuuuggug cacaaggucc aaaaggcgga agcggcagcg gaccuacaau agaagaagua     1920

gauuag                                                                1926


<210>  1232
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  1232
auggcuacag caaaaggaau agcuauugga auagaucuag gcacaacaua caguugcguu       60

ggcguuuuuc agcauggaaa aguagaaauu auagcaaaug aucaaggaaa ucgcaccacu      120

ccuucuuaug uagcuuucac agauacagaa cgacuuauag gagacgcugc uaaaaaccaa      180

guugcaauga acccacaaaa uacugucuuu gacgcaaaaa gacuaauagg ccgaaaauuc      240

aaugacccag uaguacaagc ggacaugaaa cuuuggccau uccaagugau caacgaaggu      300

gguaaaccaa aaguauuagu aucauacaaa ggagaaaaua aagcauuuua cccagaagaa      360

auaagcucua ugguacugac uaaauuaaaa gaaacagcag aagcauuucu aggacaccca      420

guaacaaaug caguaauaac aguacccgcu uacuuuaaug acucccaaag acaagcaaca      480

aaggacgcag gaguuauagc aggacuuaau guacuuagaa uaaucaacga accaacagcg      540

gcagcaauag ccuauggauu agauaaagga ggacaaggag aacgacaugu auuaauauuu      600

gaccuaggug gagguacauu cgaugucucu auauuaacca uagacgacgg aauauucgaa      660

guaaaagcaa cagcagggga cacucauuua ggcggagaag auuuugacaa uagauuagua      720

agccacuucg uagaagaguu caaaagaaaa cacaaaaagg auauaaguca gaauaaacga      780

gcaguaagaa gacuacgaac agccugugaa agagcuaaaa gaacguuauc aaguucaaca      840

caagcaaauc uagaaauaga cagucuauau gaaggaauag auuucuauac cucaauaacg      900

agagcuagau uugaagaacu augcgcagau cuauucagag gcacacuaga accaguagaa      960

aaagcucuac gagaugcaaa aauggacaaa gcuaaaauuc augauauagu ccuuguaggg     1020

ggaucaacaa gaauaccaaa aguacaaaga uuguuacaag auuacuuuaa cggaagagau     1080

uuaaacaaau caauaaaccc agaugaagcu guagcauaug gcgcagcagu acaagcagca     1140

auacuuaugg gagauaaaag ugaaaaagua caagauuuau uauuauuaga cguagcacca     1200

cuaucccuag gacuagaaac agcaggagga guaaugacag cacucauaaa aagaaauagu     1260

accauaccaa caaaacaaac ccaaauauuu acaacguaua gcgacaauca accaggagua     1320

cuaauacaag uguaugaagg agaaagagca augaccaaag auaauaaucu ucuuggccga     1380

uucgaucuca caggaauacc uccagcacca agaggagucc cacaaauuga aguuacauuu     1440

gacauagacg ccaaugguau acuaaacgua acagcuaccg auaaaaguac aggaaaagua     1500

aacaaaauca caaucacaaa ugacaaaggu agauuaucaa aagaggaaau cgaaagaaug     1560

guauuggacg cagaaaaaua uaaagcagaa gacgaaguac aaagagagaa aauagcagcu     1620

aaaaacgcuc uugaaucaua ugcauuuaac augaaaucag uaguauccga cgaaggacuc     1680

aaaggaaaaa uaagcgaauc agauaaaaau aaaauacucg auaaaugcaa cgaacuauua     1740

agcugguuag aaguaaauca acuagcagaa aaagaugaau uugaccauaa aagaaaagaa     1800

cuagaacaaa uguguaaucc aauaauaacu aaauuauacc aaggaggaug cacaggacca     1860

gccuguggca caggauaugu uccuggacga cccgcaacug gaccaacaau agaagaaguu     1920

gauuaa                                                                1926


<210>  1233
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  1233
augagcgcaa gaggaccagc gauuggaauc gaucuaggaa caacguacag uugcguggga       60

guauuccaac auggaaaagu ugaaauaauc gcaaaugauc agggaaauag aacuacacca      120

ucauacguug cuuuuacaga caccgaaaga uugauuggag acgcagcgaa aaaucaagua      180

gcaaugaauc caaccaacac aaucuuugac gcaaaaagac ucauaggcag aaaauucgaa      240

gacgcaacgg uacagagcga uaugaaacac uggccauuua gaguaguauc agaaggagga      300

aaaccaaaag uacaagucga auauaaagga gaaacuaaaa cauuuuuccc agaagaaaua      360

agcaguaugg uauuaacaaa aaugaaagaa auagcagaag cauaucuagg aggaaaaguu      420

cauagugcag uaauaacugu accagcauau uuuaaugauu cacaaagaca agccacgaaa      480

gaugccggaa caauaaccgg auuaaaugua cugagaauaa uaaacgaacc aacagcugcc      540

gcaauagcau acgggcuaga uaagaaagga ugugccggag gugagaaaaa uguauuaaua      600

uuugacuuag gcggaggaac auuugaugua ucaauacuaa caauugaaga cggaauauuc      660

gaaguuaaaa guacggcggg agauacacau uuaggaggag aagauuuuga uaacagaaug      720

guaagucauu uagcagaaga guucaaacga aaacacaaga aagacauagg accuaauaaa      780

agagcaguaa gaagacuaag gacugcaugc gaaagagcaa aaagaacacu aaguagcagu      840

acacaggcga guauagaaau agacucauua uaugaaggag ucgauuuuua uacuucaaua      900

acgagagcaa gauucgaaga acucaaugcg gauuuauuua gaggaacauu ggaaccagua      960

gaaaaagcac uuagagaugc aaaacuagac aaaggacaaa uccaagaaau aguccuagua     1020

gguggcucaa caagaauacc aaaaauccaa aaacuauugc aagauuucuu caauggcaaa     1080

gaauuaaaua agucaaucaa uccagacgaa gcagucgcau acggagcagc aguucaagca     1140

gcaauauuga uaggggauaa aucagaaaau guacaagacc uauuauuguu agauguaaca     1200

ccauuaaguc ucgguauaga aacugcagga ggaguaauga caccucuaau aaaaagaaac     1260

acaacuauac caacaaaaca aacacaaaca uuuacaacau acagugacaa ucaaucaagu     1320

guauuaguac aaguauacga aggagaaaga gcaaugacga aagacaacaa ucuauuagga     1380

aaauuugauc uaacagggau uccuccagca ccgagaggug uaccacaaau cgaaguaaca     1440

uuugacauag acgcaaaugg aauauuaaac guaacagcag cagauaaauc aaccgggaaa     1500

gaaaacaaaa ucacaauaac uaacgauaaa gggagguuaa gcaaagauga uaucgaucgu     1560

augguccaag aagcagaaag auauaaaagc gaggaugagg caaacagaga cagaguagca     1620

gcgaaaaaug cauuagaauc uuacacguau aauauaaaac aaacuguaga ggacgaaaaa     1680

uuacggggaa aaauauccga acaagauaaa aacaaaauau uagauaaaug ccaagaaguc     1740

auaaacuggu uagacagaaa ucaaauggca gaaaaagaug aauacgaaca uaaacagaaa     1800

gaacuagaaa gaguguguaa ucccauaaua ucaaaauuau accaaggagg uccaggaggu     1860

ggaagcgggg gaggaggaag uggcgcaagc ggagggccaa caauagaaga aguagauuag     1920


<210>  1234
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  1234
augucuguag uaggaauaga ccucggauuu caaaguuguu auguagcagu cgcucgggca       60

ggaggcauug aaacaauugc aaaugaauac ucagacaggu guacaccagc augcauaagu      120

uucggaccaa aaaaccgauc aauaggcgca gcagcaaaaa gccagguaau aucaaaugcu      180

aaaaauacag uacaaggguu uaaaagauuc cacggaagag cauuuucaga uccuuuugua      240

gaagcugaaa aaaguaauuu agccuacgac auaguucagu uaccaacagg auuaacaggc      300

auaaaaguaa cuuauaugga agaagaacga aacuuuacaa cugaacaagu aacagcaaug      360

cuacuaucua aauuaaaaga aacugcagaa aguguuuuaa aaaaaccagu aguagacugu      420

guaguaagcg ugccauguuu uuauacagac gcggaaagaa gaucggucau ggaugcaaca      480

caaauagcag ggcucaauug ccuuaggcuc augaaugaaa caacugcagu agcucuagcu      540

uacggaauuu auaaacaaga cuugccagca cuagaagaga aaccaagaaa cgucguuuuc      600

gucgauaugg gacacucagc auaccaagua aguguuugcg cauuuaauag aggaaaacua      660

aaaguauugg caacagcauu ugacacaaca cuaggaggua gaaaauucga ugaaguacua      720

gucaaucacu uuugugaaga auucggaaaa aaguacaaac uagauauuaa aucaaaaauu      780

agagcauuau ugcgacuaag ccaagaaugu gaaaaacuaa aaaaauuaau gucagcaaau      840

gcaucugacu uaccauuaag cauugaaugc uuuaugaaug auguagaugu cucaggaaca      900

augaaucgag gaaaauucuu agaaaugugu aacgaucuac uagcuagagu cgaacccccu      960

cucaggucag ugcuagaaca aacaaaacua aaaaaagaag auauauacgc cguggaaauc     1020

guagguggag cuaccagaau accagcugug aaagagaaaa uaaguaaauu cuucggcaaa     1080

gaauuaucaa caacacuaaa ugcagacgaa gcaguuaccc gaggaugugc uuuacaaugu     1140

gcaauuuuau cgccagcauu caaaguacga gaauucucaa uaacagaugu aguaccuuau     1200

cccauaucuc uuagauggaa uucaccagca gaagagggaa gcucagauug cgaaguauuu     1260

ucaaaaaacc acgcugcacc guuuuccaaa guacugacuu ucuacagaaa agaaccauuu     1320

acguuagaag cauacuauuc aucuccccaa gacuuaccau acccagaucc cgccauugca     1380

caauucucag uacaaaaggu gaccccacaa uccgacggau ccagcucaaa agugaaagua     1440

aagguaagag uaaauguaca cggcauauuu ucaguaaguu cagcgucccu cguagaaguu     1500

cacaaaagcg aagaaaacga agaaccaaug gaaacagacc aaaacgcaaa agaagaagaa     1560

aaaaugcaag uagaccaaga agaaccccau guagaagaac aacaacaaca aacacccgca     1620

gaaaacaaag ccgaaaguga agaaauggaa acaucacaag caggcaguaa agauaagaaa     1680

auggaucaac caccacaggc aaaaaaagcu aaaguaaaaa caaguacagu agaucuccca     1740

auugaaaauc aacuacuaug gcaaaucgau agagagaugu uaaaccuaua caucgaaaau     1800

gaaggaaaaa ugaucaugca agacaaacua gaaaaagaac ggaacgaugc aaaaaacgca     1860

guggaagagu auguauauga aaugcgagac aaacuaucag gagaauauga aaaauuuguu     1920

agcgaggaug acagaaauuc auucaccuua aaacuagaag auacugaaaa uugguuauau     1980

gaagacggag aagaccaacc uaagcaagug uacguugaua agcuagcaga gcucaaaaau     2040

uugggccagc caauaaaaau aagauuccaa gaauccgaag aaagaccgaa acuauucgaa     2100

gaacuuggga aacaaauaca gcaauacaug aagauaaucu caucauuuaa aaacaaagaa     2160

gaucaauacg accacuuaga cgcagcagac augacuaaag uagaaaaauc uacgaacgaa     2220

gcaauggaau ggaugaauaa caaacuaaau cuucaaaaca aacaaucacu uacaauggac     2280

ccaguaguaa aaagcaaaga aaucgaagcg aaaauaaaag aauuaacgag cacauguuca     2340

ccuauaauau caaaaccaaa accaaaagug gaaccaccua aagaagaaca aaaaaaugca     2400

gaacaaaaug gaccgguaga cgggcaagga gacaauccag gaccucaagc agccgaacag     2460

ggcacagaca cagcaguacc aucagacagc gacaaaaaac uaccggaaau ggacauagac     2520

uga                                                                   2523


<210>  1235
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  1235
augagugugg uaggaauaga ccuuggauuc cuaaauugcu acauagcugu agcaagauca       60

ggaggcauug aaacaauagc aaacgaauau agcgaccgau gcacaccagc augcauauca      120

uuaggaagua ggacuagagc cauagguaau gcggcaaaau cacaaauagu aaccaaugua      180

agaaacacca uacauggauu caagaaacua cacggacgca gcuucgacga uccaauagua      240

caaacagaaa gaauuagacu acccuacgaa cuacagaaaa ugccaaacgg aucugcagga      300

gucaaaguaa gauaccuuga agaagaacgg ccauuugcaa uugaacaagu gacaggaaug      360

uuacuugcaa aacuaaaaga aacaagugaa aaugcauuaa agaaaccagu agcagauugc      420

guaauuucaa uacccagcuu cuucacagac gcagaaagaa gaaguguaau ggcagcagca      480

caaguagccg gacuaaacug ucuaagacua augaacgaaa caacagcugu agcuuuagca      540

uacggcauau auaaacaaga ucuaccacca cuagaugaaa aaccaagaaa cguaguuuuu      600

auagauaugg gacacucagc cuaccaaguc cuaguaugug cuuucaacaa aggaaaauua      660

aaaguacuug caacaacauu ugauccauau cuagggggua gaaauuucga cgaagcucua      720

guagacuacu uuugugauga guucaaaaca aaauacaaaa uuaaugucaa agaaaauuca      780

agagcauuac ucagacuuua ccaagaaugc gaaaaauuaa agaaacuaau gucugcaaau      840

gcauccgauu uaccgcuaaa uaucgaaugc uuuaugaaug aucuugacgu aucaagcaaa      900

augaacagag cacaauuuga acaacuaugu gcauccuuau uagcaagagu agaaccuccc      960

cuaaaagcgg uaauggaaca agcuaaucuc caacgcgaag acauaagcuc aauagaaaua     1020

guaggcggag caaccagaau accggcagug aaagaacaaa uaacaaaauu uuucuuaaaa     1080

gacauuucua caacuuuaaa cgcagacgaa gcuguggcua gagguugcgc acuucaaugc     1140

gccaucuuau caccagcguu caaaguccgc gaguucagua uaacagaccu gguaccauac     1200

aguaucacgc uccgauggaa aacuagcuuu gaagacggcu cuggggaaug cgaaguauuc     1260

uguaaaaauc acccagcacc auuuagcaaa guaauaacau uucacaagaa agaaccauuc     1320

gaacuagaag cauucuacac aaacuuacau gaaguucccu acccagaugc acgaauaggu     1380

aguuucacaa uacaaaaugu auucccacaa uccgacggag acucaucuaa agucaaaguc     1440

aaagugcggg uaaacauaca uggaauauuc uccguugcaa gugcaagugu gauagaaaaa     1500

caaaaccucg aaggggauca uucagacgca ccuauggaaa cggaaacaag uuucaaaaac     1560

gaaaacaaag auaauaugga caaaaugcaa guagaucaag aagaaggaca ccaaaaaugc     1620

caugcggaac auacucccga agaagaaaua gaucauacag gugcuaaaac aaaaucagca     1680

guauccgaca aacaagacag gcuaaaucaa acacucaaga aaggaaaagu aaaaaguaua     1740

gaccugccga uacaaagcag ucucugucga caauuaggac aagauuuacu aaauaguuac     1800

auagaaaaug aagggaaaau gauuaugcaa gauaaauuag aaaaagaaag gaacgaugcc     1860

aaaaaugcug uugaagaaua cguauaugac uuucgcgaca gauuaggaac aguauacgaa     1920

aaauuuauaa cccccgaaga ccuaaguaaa cuaucugcag uacuagaaga cacagaaaau     1980

ugguuauaug aagauggaga agaucagcca aaacaaguuu acguagauaa acuacaagag     2040

cuuaagaaau acggacaacc aauucaaaug aaauauaugg aacaugaaga acgcccgaaa     2100

gcauuaaacg acuuaggaaa gaaaauacaa uuaguaauga aaguaauaga ggccuacaga     2160

aacaaagaug aaagguauga ccaccucgau cccacagaaa uggaaaaagu ugaaaaaugc     2220

auaucagacg cuaugucaug gcuaaacagc aaaaugaacg cccaaaacaa auuaucacuu     2280

acucaggauc cuguaguaaa aguaagcgaa auaguagcga aaagcaaaga acuagacaac     2340

uuuuguaacc cuauaaucua uaaaccuaaa cccaaagcag aaguaccaga ggauaaaccc     2400

aaagccaauu cugaacauaa ugggccaaug gauggacaau ccggcacaga aacaaaaucg     2460

gacaguacca aagacucauc acagcacaca aaaagcagug gagaaaugga aguugacuaa     2520


<210>  1236
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  1236
augaaacucu cacuaguagc agcgauguua uuacuuuuaa gugcugcacg agcagaggaa       60

gaagauaaaa aagaagacgu agguacagua guagguauag accuaggaac aacauacuca      120

uguguaggag uauucaagaa uggacgagua gaaauuauag caaaugauca aggcaauaga      180

auaacaccaa guuauguagc uuucacaccc gaaggagaaa gauuaauagg ggacgcagcu      240

aaaaaccaau uaacaagcaa uccagagaac acaguauuug acgcaaaaag auuaaucggc      300

agaacaugga augaccccuc uguacaacaa gauauuaaau uucuaccguu uaaaguggua      360

gaaaaaaaaa caaaaccuua uauacaagua gacauaggag gaggacaaac gaaaacauuc      420

gcuccagaag aaauaagcgc aaugguuuua acuaaaauga aagaaacagc ggaagcauau      480

uuaggaaaaa aaguaacuca cgcuguagua acagucccag cauacuuuaa cgaugcucaa      540

agacaagcca caaaagaugc aggaacaauu gcaggcuuaa auguaaugag aauaauaaau      600

gaaccuacag cagccgcaau agcguacgga cuagacaaaa gagaaggcga aaaaaacaua      660

cuaguauuug auuuaggagg aggaacauuc gauguaaguc uacuuacaau ugacaacgga      720

gucuuugaag uaguagccac aaauggagau acgcaucuag gaggagagga cuucgaccaa      780

aggguuaugg aacacuucau aaaauuauac aaaaaaaaaa caggaaaaga cguuagaaaa      840

gacaauagag ccguacaaaa auuaagacga gagguagaaa aagcaaaaag agcauuguca      900

agccaacacc aagcaagaau agaaauagaa ucauuuuaug aaggagagga cuucagcgaa      960

acacuuacaa gagcaaaauu ugaagaacug aauauggauu uauuuagaag uacaaugaaa     1020

ccaguucaaa aagucuuaga agauagugau uuaaaaaaaa gcgacauaga ugaaauagua     1080

cucguaggag gaucaacaag gauaccaaaa auacaacaau uaguuaaaga guuuuuuaau     1140

ggaaaagaac caucacgagg aauaaaucca gacgaagcag uagcauacgg agcagcagua     1200

caggcaggag uacuaagcgg agaucaagau acaggagauc uagucuuacu agaugucugc     1260

ccacuuacau uaggaaucga aaccguagga gggguaauga caaaacuaau accacguaac     1320

acgguugugc caacaaaaaa aucacagaua uucaguacag cgucagacaa ucagccaacc     1380

gucacuauaa aaguauacga aggagaacga ccacuuacaa aagauaacca ucuacuagga     1440

accuucgauu uaacaggaau accacccgcc ccaagaggag uaccacaaau agaaguuaca     1500

uucgaaauag acguaaacgg uauucuuaga gugacagcug aagacaaagg aaccggaaau     1560

aaaaauaaaa uaacaauaac uaacgaucaa aaccgacuaa cuccagaaga aauagaacgc     1620

augguaaacg augcagaaaa auuugcagaa gaagacaaaa aacuaaaaga acgaaucgau     1680

acuagaaaug aacuagaauc auacgcauau ucauuaaaaa aucaaauagg cgacaaagaa     1740

aaacuaggag gaaaauuauc aagugaggau aaagaaacua uggaaaaagc ggucgaagaa     1800

aaaauagagu gguuagaaag ucaucaagac gcugauauag aagauuuuaa agcaaaaaaa     1860

aaagaauuag aagagauagu acaaccaaua auaucaaaac uauauggaag cgccgguccu     1920

ccaccaacag gcgaagaaga cacagcugaa aaagacgaau uauga                     1965


<210>  1237
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  1237
augcaagccc caagagaauu agcaguugga auagaccuag guacaacaua cucaugugua       60

ggaguuuuuc aacaaggaag aguugagaua cuagcaaaug aucaaggaaa cagaacaaca      120

cccagcuaug uagcauucac ugacacagaa agauuagucg gagacgccgc aaaaucacaa      180

gcagcucuaa acccucauaa uacaguuuuu gaugcuaaaa ggcuuauagg gagaaaauuc      240

gcagacacaa caguacaauc agauaugaaa cacuggcccu uucgaguagu aucagaagga      300

ggaaaaccga aaguaagagu uugcuauaga ggagaagaua aaacauuuua cccagaagaa      360

aucucaucaa ugguucuuag uaagaugaaa gagacagcgg aagcauacuu aggacaaccg      420

gucaaacacg ccguuauaac aguaccugca uauuucaaug acagucaaag acaagcuaca      480

aaagaugcag gagcaauagc aggauuaaau guauuaagaa uuauuaauga accaacagcc      540

gcagcaauag cauacggacu agaucguaga ggagccggag aaagaaacgu cuuaauauuu      600

gauuuaggag ggggaacauu ugauguauca guucuaucga uagaugcagg aguauuugaa      660

guaaaagcua cagcaggaga uacacauuua ggcggggaag auuuugauaa cagauuagua      720

aaucacuuca uggaagaauu uagaagaaaa cacgguaagg acuuaucagg aaauaaacga      780

gcacucagaa gacuuagaac agccugugaa cgagcaaaac guacuuugag cucaaguaca      840

caagcuacuu uagaaauaga caguuuauuc gaagguguug auuuuuacac aaguauuacu      900

agagcaagau uugaagaacu auguucagau uuauuucguu caacauuaga accaguagaa      960

aaagcacuaa gagaugcaaa acuagauaaa gcucaaauac augauguggu gcuaguagga     1020

gguuccacaa ggaucccaaa aguccaaaaa cuacuacaag auuucuuuaa uggcaaagaa     1080

cucaacaaaa guauaaaucc cgaugaagca guagcauaug gugcagcagu acaagcagca     1140

guuuuaaugg gagauaagug ugaaaaagua caagauuuac uauuacuaga cguagcaccc     1200

cuaucacucg gacuagaaac agcuggagga guaaugacua cacuaauuca aagaaacgcc     1260

acaaucccaa caaaacaaac acaaacauuu acaacauacu cagauaauca accaggcgua     1320

uuuauacagg uuuacgaagg ugaacgagca augaccaaag acaauaaucu acucgguaga     1380

uucgaacuaa guggaauacc accagcccca agaggaguac cacaaauaga aguaacauuu     1440

gauauagaug caaaugguau ucucagcgua acugcaaccg accguagcac aggaaaagcu     1500

aacaaaauaa cuauaacgaa ugauaaagga agacuaagua aagaagaagu agaacgcaug     1560

guacaugaag cagaacaaua uaaagcagaa gacgaagcac aaagagauag aguugcagcu     1620

aaaaacaguu uagaagcaca uguguuccau guaaaaggau cauuacaaga agaaucauua     1680

agagauaaaa uuccagaaga agauagacga aaaaugcaag auaaaugcag agaaguacuc     1740

gcauggcuag agcacaauca auuagcagag aaagaggaau augaacacca gaaacgagaa     1800

uuagaacaaa uuugucgacc aauauuuagu agguuauacg gaggaccagg agucccagga     1860

gguucaucau guggaaccca agcaagacaa ggagauccca guacaggucc aauaauagaa     1920

gaaguugacu aa                                                         1932


<210>  1238
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__P48741__HsHSPA7

<400>  1238
augcaagcuc caagagaacu agcuguagga auagauuuag gaacaacaua uaguugugua       60

ggaguauuuc aacaaggaag aguugaaaua cuagcaaaug aucaagggaa uaggacaaca      120

ccaucauaug uagcauuuac agauacagaa cgauuaguag gagaugcagc aaaaucacag      180

gcagcucuaa acccacauaa uacaguauuu gaugcaaaaa gacuaauagg uagaaaauuu      240

gcagacacua caguacaaag cgauaugaaa cauuggccau uucaaguagu aucagaaggu      300

ggcaaaccaa aagucagagu auguuauaga ggagaagaua aaacuuuuua ucccgaagaa      360

auaucaucaa ugguauuaag uaaaaugaaa gaaacagcag aagcauaucu aggacaacca      420

guaaaacaug cgguaauaac aguuccaaca uauuuuucaa acucacaaag acaagcaaca      480

aaagaugccg gugcaaucgc aggacuuaaa guauuaccaa uaauuaauga agcaacagca      540

gcagcaauag cauauggacu agauagaaga ggagcuggaa aaagaaaugu auuaauauuc      600

gauuuaggag guggaaccuu ugauguauca guauuaagca uagaugcagg aguauuugaa      660

gucaaagcaa cagcaggaga uacacaucua ggaggggaag auuucgauaa uagauuagua      720

aaucacuuua uggaagaguu uagaagaaaa cauggaaaag auuuaagcgg uaauaaaaga      780

gcauuaagaa gacuaagaac agcaugcgaa agagcaaaaa gaacaccauc aagcaguacg      840

caagcaacau uagaaauaga cucauuauuc gaaggaguag acuuuuauaa aucaauaaca      900

agagcgagau ucgaagaauu augcucagac uuauucagaa guacacuaga accaguagaa      960

aaagcauuaa gagaugcaaa acuugacaaa gcacaaauac augauuucgu acuaggagga     1020

ggauuacaca gucauccaca aggagcugaa guagcagcag gacuauuaca acgacaaggu     1080

gcagaacaag aacaucaacc auag                                            1104


<210>  1239
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  1239
augucaaaag guccggcagu aggaaucgau uuaggaacaa cauauaguug ugucggagua       60

uuucaacaug gaaaaguuga aauaauagca aacgaucaag gcaauagaac uacaccaucu      120

uacguugcau uuacagauac agaaagauua auaggggacg cagcuaaaaa ccaaguagca      180

augaacccaa caaauacagu auuugacgca aaacgacuaa uaggaagaag auuugaugau      240

gccguuguac aaucugacau gaaacauugg cccuuuaugg uaguaaauga cgcaggaaga      300

ccaaaagucc aagucgaaua caaaggagaa acaaagagcu uuuacccuga agaaguuucu      360

agcauggucc uaacaaaaau gaaagaaauu gcagaagcgu accuaggcaa aaccguaaca      420

aacgcagucg ugacaguacc agcauauuuu aacgauucac aaagacaggc aacaaaagac      480

gcaggaacaa uugcaggacu caacguacuc cgaauaauaa augaaccaac ugcugcagca      540

aucgcauaug gguuagacaa gaaaguagga gcagagcgca auguacuaau auuugaccua      600

ggaggaggua cguucgaugu aagcauauua acaauagaag auggcauauu ugaaguaaaa      660

uccacagcag gagacacaca cuuaggagga gaagauuuug acaauagaau ggucaaccau      720

uucauugcag aguucaaaag aaaacacaag aaagauauuu cagaaaauaa aagagcagua      780

agaagauuaa gaacagcuug ugaaagagcu aaaagaacuu uaucaucauc aacacaagcu      840

agcauagaaa uugacaguuu auaugaagga auagauuucu auacauccau cacgcgagca      900

agguuugaag aauuaaaugc agacuuauuu cgaggaacac uugacccugu ugaaaaagcc      960

cuacgagacg cuaaacuaga caaaagccaa auacaugaca uaguucuagu aggaggaagc     1020

acuagaauac ccaaaauaca aaagcuacug caagacuucu ucaacggaaa ggaacucaac     1080

aaaagcauua aucccgauga agcaguagcu uacggagcug caguacaagc ugcaauauua     1140

aguggagaca aaagcgaaaa cguacaagau cuacuauuac uagauguaac accucuaagc     1200

cucggaauag aaacggcagg aggagugaug acaguacuca uaaaaagaaa uacuacaaua     1260

ccaaccaaac aaacacaaac auuuacaaca uacucagaca aucaaccagg aguauuaaua     1320

caaguauacg aaggagaaag agccaugaca aaagacaaua aucuccuagg aaaauucgaa     1380

uuaacaggaa uaccaccagc accucgcgga guaccacaaa ucgaaguaac cuuugacauu     1440

gaugcgaacg gcauauuaaa uguuucagcc gucgacaagu cuacaggaaa agagaacaag     1500

auaacaauaa cuaaugauaa agggcgauua agcaaagaag auauagaacg aaugguacaa     1560

gaagcagaaa aauauaaagc agaagaugaa aaacaaagag auaaaguauc uagcaaaaau     1620

agccuagaaa guuaugcauu caauaugaaa gccacaguug aagacgaaaa auuacaaggc     1680

aaaauaaaug acgaagauaa acagaaaaua uuagacaaau guaacgaaau aauaaacugg     1740

cuggauaaaa aucaaacggc cgaaaaagaa gaauuugaac aucaacaaaa agaauuagaa     1800

aaaguaugca auccgauaau aacaaaauua uaccaaucag cuggggguau gccagggggu     1860

augccaggug gauucccagg agggggagca ccaccaagcg gaggagcaag cucaggacca     1920

acaaucgaag aagucgacua a                                               1941


<210>  1240
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  1240
augauauccg caucaagagc agcagcggca agauuaguag gagcagcagc aaguagagga       60

ccaacagcag caagacacca agacaguugg aaugguuuaa gccaugaagc auuuagacuc      120

gugaguagga gagauuaugc aagugaagcc auaaaaggag cugugguagg aauagauuua      180

ggaacaacua auucaugugu ugcaguaaug gaaggaaaac aggcuaaagu acuagagaau      240

gcggaaggag cuagaaccac ucccagugua guagcauuca cagcugaugg agaaagauug      300

guagggaugc cggcaaaaag acaagcaguu acgaacccaa auaacacauu uuaugcaaca      360

aaacgacuaa uagggaggcg auacgaugac ccggaaguuc aaaaagauau uaaaaacguu      420

ccuuuuaaga uaguaagagc cagcaaugga gaugccuggg uagaagccca cggaaaguua      480

uauucaccaa gucaaauagg ggcuuuugua cuaaugaaaa ugaaagaaac agccgaaaau      540

uacuuaggac auacugcuaa aaaugcaguu auaacaguac cagcauauuu uaaugauagc      600

caaagacaag cuacaaaaga ugcaggucag auaagugguc ucaacguucu gcgcguaauu      660

aaugaaccaa cagcugcugc acuagcauac ggguuagaua aaagugaaga uaaagucaua      720

gcgguauaug auuuaggagg aggcacauuu gauauaucaa uauuagaaau acaaaaaggg      780

guauucgaag uuaaaagcac caauggagau acguuucuug gaggggaaga uuuugaccaa      840

gcguuauuaa gacauauagu gaaagaauuu aagagagaga caggaguaga ucuaacaaaa      900

gacaacaugg cauuacaaag aguuagagaa gcugcugaga aggcaaaaug ugaauuaagc      960

ucaaguguac aaacagauau aaauuuaccc uauuuaacaa uggauagcag uggaccgaaa     1020

caucuaaaua ugaaauugac cagagcucaa uuugaaggaa uagugacaga uuuaauaagg     1080

agaacaauag caccaugcca gaaagcaaug caagaugcag aggugaguaa aagcgauauc     1140

ggagaaguga uauugguagg aggaaugaca agaaugccaa aaguacaaca aacaguacaa     1200

gacuuauuug gcagagcacc aagcaaagcu guuaacccag augaagcagu ggcuauugga     1260

gcagcuauac aaggaggagu guuagcagga gauguaacag auguauuauu acuagaugua     1320

acaccauuau cauuggguau agaaacacua ggagggguau uuacaaagcu aauaaauaga     1380

aauacaacaa uaccaacaaa gaagucucaa guauucucaa cugcagcaga ugggcaaaca     1440

caaguagaaa uaaaaguaug ucaaggagaa agagaaaugg caggcgacaa uaaacuacuu     1500

ggacaauuua cacuaauagg cauaccgccc gcccccaggg gaguuccaca aauagaagua     1560

accuucgaua uagaugccaa cggaauagua cacguaagcg caaaggacaa agggacaggg     1620

agagaacaac aaauaguaau acaauccagc ggagguuuau caaaagacga cauagaaaac     1680

augguuaaaa augcagagaa guaugcagaa gaagauagaa gaaagaaaga aagaguagaa     1740

gcaguaaaua uggcagaggg uauuauacau gauacggaaa caaaaaugga agaauuuaaa     1800

gaucaauuac cugcagacga augcaauaaa cuaaaagaag aaauaagcaa aaugagagaa     1860

uuacuagcaa gaaaagauuc ggaaacugga gaaaauauaa gacaagcagc uaguagccug     1920

cagcaagcca gcuuaaaacu auucgagaug gcauauaaga aaauggcaag cgaaagagaa     1980

ggcaguggga gcucaggaac aggugaacaa aaagaagacc aaaaagaaga aaaacaauaa     2040


<210>  1241
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  1241
auggcugaua aagaagcugg agguucugau ggaccacgag aaacagcucc aacuucugcu       60

uacucaaguc cagcaagguc uuuaggagac acgggaauua ccccguuaag ucccagucau      120

auagucaacg auacugauuc uaacgugucc gaacaacaaa gcuuucuugu aguaguagca      180

guugacuucg gaacuacuuc aucaggauau gcguauucau uuacaaaaga accagaaugu      240

auccacguga ugagacgaug ggaaggagga gaucccggag uaagcaauca aaaaacaccg      300

acaacaauac ucuuaacacc agaacgaaaa uuccauucau uuggcuacgc agcuagagau      360

uucuaucaug aucuagaucc aaaugaagca aaacaauggu uauaucuuga aaaauuuaaa      420

augaaacuac auacaacagg ugaccucaca auggauacug aucuaacagc agcaaauggg      480

aagaaaguua aagcacuaga aauauuugca uacgcccuuc aauacuuuaa agaacaagca      540

cuuaaagaac uaucagauca agcaggaucu gaauuugaaa auagcgaugu uagaugggua      600

auaacaguuc cagcaauaug gaaacaacca gcaaaacaau uuaugcgcca agcugcauac      660

caagcaggac ucgccucucc agagaauuca gaacaauuaa uaauugcauu agaaccugaa      720

gcagccagua uauauugcag aaaacuaaga uuacaucaaa ugauugaauu aaguaguaaa      780

gcagcaguaa acgguuauag ugguucagau acaguaggag cuggcuuuac ucaagcaaaa      840

gaacauauaa gaagaaauag acaaucaagg acauuuuuag uagaaaaugu aauuggugaa      900

auaugguccg aauuagaaga aggagacaaa uauguagucg uagacucugg uggcggaacu      960

guagaccuaa caguacauca aauaagacuu ccagaaggac aucuaaaaga auuauauaaa     1020

gcaacgggag gccccuaugg aucauuaggu guagauuaug aauucgaaaa auuauuauau     1080

aaaauauuug gcgaagauuu uauagaacaa uucaaaauaa aaagaccugc ggcuugggua     1140

gacuuaauga uagcuuuuga aucaagaaaa agagcugccg ccccagacag aacaaaucca     1200

uuaaauauaa cauuaccauu uucauuuauu gauuauuaua aaaaauuuag aggacacucu     1260

guagaacaug cacuuagaaa aagcaacgua gauuuuguaa aauggaguuc ucaaggaaug     1320

uuaagaaugu caccagacgc aaugaacgcc uuguucaaac caacgauuga uaguauaaua     1380

gaacacuuac gcgacuuauu ucaaaaacca gaaguaucaa cagucaaauu ucuauuuuua     1440

gucggaggau uugcagaagc accacuucua caacaagcag uacaagcagc auuuggagau     1500

caaugcagaa ucauaauacc ucaagacgua ggccucacga uucuaaaagg cgcagugcua     1560

uucggucuag auccagcagu uauaaaaguu cggcgaucac ccuuaacaua uggaguugga     1620

guauuaaauc gauacguaga aggaaaacau ccaccagaaa aauuauuagu aaaagacggu     1680

acgagauggu guaccgaugu auucgauaaa uuuauaucag cagaccaauc aguagcucuc     1740

ggcgaacucg uuaaaagauc cuauacacca gcaaaaccau cucaauuagu uauaguaauu     1800

aauauauauu caagcgagca cgauaacguu ucauuuauaa cagauccagg uguaaaaaag     1860

ugcgguacau uaagacucga cuuaaccgga acaaguggaa cagcaguucc agcacgcaga     1920

gaaauacaaa cauuaaugca auuuggugau acugaaauaa aagcaacagc cauagacaua     1980

gccacaucaa aaucaguuaa aguuggaaua gacuuucuaa auuacuga                  2028


<210>  1242
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  1242
auguuagcag uaccagaaau gggauuacag ggacuauaua uuggaucuuc uccagaaaga       60

ucaccaguac caucaccacc cgggucacca agaacccaag aaagcugugg aauagcucca      120

cuaacaccau cacaaucccc uaaaccagaa guaagggcac cccaacaagc caguuucagu      180

guuguaguag caauagauuu uggaacuaca ucaucagguu acgcauuuuc cuuugcauca      240

gauccugaag caauucauau gaugagaaaa ugggaaggag gagacccugg cguagcacau      300

cagaaaacuc cuacauguuu acuuuugaca ccagaaggag cauuucauuc auuuggauau      360

acagcacgag auuauuauca cgacuuagau ccagaagaag cuagagauug gcucuacuuu      420

gaaaaauuua aaaugaaaau acauagugca acagaucuaa cauuaaaaac ccaauuagaa      480

gcuguuaaug guaaaacuau gccagcgcua gaaguauuug cgcacgcauu aagauuuuuc      540

cgagaacaug cauuacaaga acuuagagaa caaucaccuu cacuaccuga aaaagauaca      600

guuagauggg uauugacugu accggcaaua uggaaacaac cagcgaaaca auuuaugaga      660

gaagcugcau auuuagcugg guuaguauca cgagaaaaug cagagcaacu cuuaauugcg      720

cuugagccag aagcagcauc ugucuacugc agaaaauuaa gacuacauca acuacuagau      780

uuaaguggca gagcacccgg agguggaaga cuaggugagc gaagaagcau agauucaagu      840

uuccgacaag caagagagca acuaagacga ucaagacacu caagaacauu ucuaguagaa      900

agcgguguag gagaauuaug ggcagaaaug caagcaggag aucgauaugu aguugccgau      960

ugcgggggug gcacaguaga uuuaacaguc caucaacuag aacaaccaca cggaacucua     1020

aaagaacuau auaaagcauc aggaggucca uacggcgcag uaggagugga cuuagcguuc     1080

gaacaacuac uaugcagaau auuuggagaa gauuuuauag cgacauuuaa aagacaaaga     1140

ccugcggccu ggguagaucu aacaauagca uucgaagcaa gaaaacggac ggccgggccg     1200

cauagagcag gagcucuaaa uauaagccua ccauuuucau uuauagacuu uuauagaaaa     1260

cagagaggac auaacguuga aacugcacug agacgauccu caguaaauuu cguaaaaugg     1320

ucuucacaag gaauguugcg aaugagcugc gaagcaauga augaacuauu ucaaccaacu     1380

guaaguggca uuauucaaca uauagaagca cuauuagcaa gaccugaagu ccaaggaguu     1440

aaacugcuau uccugguagg uggauuugca gaaucggcag uauuacagca ugcaguacaa     1500

gcagcuuuag gugcaagagg auuacgagua guaguaccac augauguagg acuaacaauu     1560

uuaaaaggag cuguacuauu cggccaagcu ccaggaguug uaagaguuag aagaagucca     1620

uuaaccuacg ggguaggggu acuuaauaga uucguaccug gacgacaucc accagaaaaa     1680

uuauuaguaa gggauggaag acgcuggugu acagaugugu ucgaaagauu cguagcugcu     1740

gaacagagcg uugcucuagg ggaagaagua cgaagaucau acuguccagc uagaccaggc     1800

caaaggcgag uauuaauaaa uuuauauugu ugugcagcag aagaugcaag auucaucacu     1860

gauccaggag uuagaaaaug cggagcacuc ucucuagagu uagaaccugc ggacugugga     1920

caagacaccg caggagcccc accaggaagg agagaaauac gagcagcaau gcaauuuggu     1980

gauacagaaa uuaaagucac ugcaguagau guaucgacaa auagaucagu aagagcuucg     2040

auugauuucc uuucgaauua a                                               2061


<210>  1243
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  1243
auggcucgag aaaugacaau uuuaggauca gcgguauuga cacuuuuauu agcaggauac       60

cuagcccaac aauaccuacc acuaccuaca ccaaaaguga uaggaauaga ccuuggaaca      120

acauacuguu caguaggagu auucuuucca ggaacaggua aaguaaaagu aauaccagau      180

gaaaacggac acauaaguau acccucaaug guaaguuuua ccgauaacga uguauacgua      240

ggauacgaau caguugaauu agcagacuca aauccacaaa acacaauaua ugacgcaaaa      300

agauuuaucg gaaaaaucuu cacagcagag gaauuagaag cagaaauagg aagauauccc      360

uucaaaguau uaaauaaaaa cggaauggua gaauucucug ucacaucaaa cgaaacaaua      420

acaguaagcc cagaauacgu aggcagucga uuacuacuaa aacucaaaga aauggcagaa      480

gcguacuuag gaaugccagu agcaaaugcc guaauaucag ucccagcaga auucgaucua      540

aaacaacgaa acagcaccau agaagcagcc aaucuagcag gauuaaaaau acuaagagua      600

auaaacgaac caaccgcagc agccauggca uauggacuac acaaagcaga uguauuucac      660

guauuaguaa uugaucuagg aggcggaacc uuagacguau cauuauuaaa uaaacaagga      720

ggaauguucu uaacuagagc caugucagga aauaacaaac uaggaggaca agauuuuaac      780

caacgacucu uacaauacuu auacaaacaa auauaucaaa cauauggauu uguuccuagc      840

agaaaagaag aaauacauag acuaagacaa gccguagaaa ugguuaaauu aaaucuuaca      900

cuccaccaaa gugcacaacu aagcguguua cuaacaguag aagaacaaga cagaaaagaa      960

ccacacucuu cagacacaga auuaccaaag gauaaauuau caucagcaga ugaccaccga     1020

guaaauucag gauucggaag aggacuauca gauaaaaaau caggagaauc acaaguucua     1080

uucgaaacag aaauaucaag aaaacuauuu gacacauuaa acgaagauuu auuccaaaaa     1140

auacuaguac caauacaaca aguacuuaaa gaaggacauc uugaaaaaac ggaaauagac     1200

gaaguaguac ucguaggagg uucaacaaga auaccaagaa uaagacaagu aauucaagaa     1260

uuuuuuggaa aagacccaaa uacauccgua gauccagauc uagccguagu aaccggcgua     1320

gcuauacaag caggaauaga ugguggauca uggccauuac aaguaucagc acucgaaauc     1380

ccaaacaagc acuuacaaaa aacaaauuuc aacuaa                               1416


<210>  1244
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  1244
auggcagcaa ucggaguuca ucuaggaugu acaagcgcau gcguagcagu auacaaagac       60

ggucgagcag guguugucgc aaacgaugca ggagauagag uaacaccagc uguaguagca      120

uauagugaaa acgaagaaau aguaggauua gcagcaaaac aaagcaggau ucgaaauaua      180

ucaaauacag uaaugaaagu aaaacaaaua uuaggccgaa gcagcuccga cccucaagca      240

caaaaauaua uagcagaaag uaaauguuua guaauagaaa aaaauggaaa acuaagauac      300

gaaauugaua cgggagaaga aacaaaauuc guaaauccgg aagauguagc aaggcuaaua      360

uuuagcaaaa ugaaagaaac agcucauagu guauuaggaa gcgacgcaaa cgacguaguu      420

auaacagucc cuuucgauuu uggagaaaaa caaaaaaaug cucuuggaga agccgcaaga      480

gcagccggcu uuaauguacu aagacuaaua caugaaccau cagcagcucu auuagcauau      540

ggaaucggac aagauucacc aacagguaaa aguaacauac uaguauuuaa auuaggagga      600

acaucauuau cacuauccgu aauggaagua aauucaggaa ucuauagagu auuaaguaca      660

aacacagacg acaacauugg aggagcacac uuuacagaaa cuuuagcaca auaucuugca      720

uccgaauuuc aaagaaguuu uaaacaugac guaagaggua acgcaagagc gaugaugaaa      780

cugacaaauu cagcagaagu agcaaaacau agucuaucaa cauuaggauc cgcaaacugc      840

uuucuagaua guuuauauga aggacaagac uuugacugca auguaucaag agcacguuuc      900

gaacucuuau guucaccguu auuuaauaaa ugcauagaag caauaagagg acuauuagau      960

caaaauggau uuacagcuga ugauauaaau aaaguugugu uauguggagg aucaucaaga     1020

auaccaaaau uacaacaauu aauaaaagau uuauuucccg caguagaauu auuaaauuca     1080

auaccaccag acgaaguaau uccaauaggc gcagccaucg aagcaggcau acuaauagga     1140

aaagaaaacc uauuaguaga agacucauua augauagaau guucagcaag agauauauua     1200

guaaaaggag uagaugaaag uggugcguca agguuuacag uauuauuucc aagcggaaca     1260

ccacuaccug caagaagaca acauacgcua caagcaccag guaguauaag uucaguaugu     1320

cuagaacuau augaauccga cggaaaaaac agcgcaaaag aagaaacaaa auuugcacaa     1380

guuguuuuac aagauuuaga uaaaaaagaa aacggcuuaa gagacauuuu agcaguauua     1440

acaaugaaac gcgauggauc acuacaugua acauguacag accaagaaac aggaaaaugc     1500

gaagcaauaa guauagaaau agcuucauaa                                      1530


<210>  1245
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  1245
augucaguag uaggacuuga uguaggauca caaucauguu acauagcagu agcuagagcc       60

ggugggauag aaacaauagc aaacgaauuu agugauagau gcacaccaag ugucauauca      120

uuugguagca aaaacagaac aauaggagua gcagcgaaaa accaacaaau aacccacgca      180

aacaacacag uaucaaacuu caaaagauuc cacggcagag cauuuaacga ccccuucaua      240

caaaaagaaa aggaaaacuu gaguuaugac uuaguaccac ucaaaaaugg aggaguugga      300

auaaaaguaa uguacauggg ggaagaacac uuauuuagcg uagaacaaau uacugcaaug      360

cuauuaacaa aacuuaaaga aacagcagaa aacucauuaa agaaaccagu aacagauugu      420

guaaucuccg uaccaucuuu cuuuacagau gcagaaagac gauccgucuu agacgcagca      480

caaauaguug gccuaaauug uuuaagguug augaacgaca ugacugccgu agcccuaaau      540

uaugguauuu acaaacaaga cuuaccaagc cucgaugaga aaccccggau aguaguauuu      600

guagacaugg gacacagcgc auuucaagug agugccugug ccuuuaacaa aggaaaacuc      660

aaaguucucg guaccgccuu ugauccguuu uuaggaggca aaaauuucga cgaaaaauua      720

gucgaacauu uuugcgcaga auuuaaaaca aaauauaaau uagacgcgaa aagcaaaaua      780

agagcgcuac ugagauuaua ccaagaaugu gaaaaacuaa agaaacuaau gaguucaaau      840

aguacagacc uaccacuaaa uauagagugu uucaugaacg acaaagacgu aagcggaaaa      900

augaauagau cacaguucga agaacuuugu gcagaacuau uacagaaaau agaaguuccc      960

uuauauucau uauuagaaca aacacacuua aaaguagagg augucucagc uguagaaauc     1020

gucggaggag ccacccguau uccagcgguc aaagaaagaa uagcaaaauu cuuuggcaaa     1080

gacauaagua caacccuaaa cgccgaugaa gcagucgcaa gaggaugugc acuccaaugu     1140

gcaauccuua guccagccuu uaaaguaaga gaguuuuccg uaacugacgc aguaccauuu     1200

ccuauuucuc uaauuuggaa ucaugauuca gaagauacag aaggaguaca ugaaguauuu     1260

ucaagaaacc augcagcacc guucaguaaa guauugacau uuuugcgaag aggcccauuc     1320

gaacuagaag cauuuuacuc agauccacaa gggguaccau accccgaagc aaaaaucgga     1380

agauuuguug uacaaaacgu cucagcacaa aaagauggag agaaaagcag aguaaaagua     1440

aaaguacgag uaaacacuca uggaauauuc acaauaucua ccgcaagcau gguagaaaaa     1500

gucccaacag aagaaaacga aaugucaagc gaagccgaua uggaaugcuu gaaucaacga     1560

ccgcccgaaa acccagauac ugacaaaaac guacaacaag auaauucaga agcuggaacu     1620

caaccacagg uacaaaccga ugcacaacaa accucacaaa gcccaccaag ucccgaacuu     1680

acguccgaag aaaacaaaau accagacgca gauaaagcaa acgagaagaa agucgaccaa     1740

ccaccagaag caaagaaacc gaaaauaaaa guagugaaug uagaauuacc aauagaagcc     1800

aaccuagugu ggcaacuagg aaaagaccuc cuaaacaugu acauugaaac agaaggaaaa     1860

augauaaugc aagauaaauu ggagaaagaa agaaacgacg ccaaaaaugc aguagaagaa     1920

uacgucuacg aguucagaga uaaacuaugu gguccauaug aaaaauucau augugaacaa     1980

gaucaccaaa auuuccuuag auuacuuaca gaaacugaag auugguuaua ugaagaaggc     2040

gaagaucaag caaaacaagc cuacgucgac aaauuagaag aauuaaugaa aauaggaaca     2100

ccagugaaag uaagauucca agaagcagaa gaaagaccaa aaauguuuga agaauuaggu     2160

cagcgcuuac aacauuacgc caaaauugca gcagauuuua gaaauaaaga ugaaaaauau     2220

aaccauauug acgaaucaga gaugaagaaa guagaaaaau cagucaauga aguaauggaa     2280

uggaugaaua auguaaugaa cgcucaagca aagaaaucau uagaccaaga cccaguagug     2340

agagcccaag aaauaaaaac aaaaauaaaa gaauuaaaua auacauguga accuguuguu     2400

acacaaccaa aaccaaaaau agaaagucca aaacuagaac gaacgccaaa cggaccaaau     2460

auagacaaga aagaagaaga ucuagaagac aaaaauaacu ucggugcaga accuccacau     2520

caaaacggag aauguuaccc aaacgagaaa aacaguguaa acauggacuu agacuaa        2577


<210>  1246
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  1246
auggccgaua aaguaaggcg ccaacgucca agaagaagag uauguugggc acuuguugca       60

guucuacuug cagacuuauu agcacuaagu gauacacuug cagugaugag uguagaucuu      120

ggauccgaaa gcaugaaagu agcaaucgua aaacccggag uaccaaugga aauuguacuc      180

aacaaagaaa gucgaagaaa aacaccagua aucguaacuc uaaaagaaaa ugaaagauuu      240

uucggggauu cugcagcauc uauggcaauu aaaaacccaa aagcuacauu acguuacuuc      300

caacauuuac uugguaagca agcagauaac ccucacguug cucuauauca ggcucguuuc      360

ccagaacaug aacucacauu cgacccacaa cgacagacag uacacuuuca aauaucaagc      420

caauuacaau ucucaccaga agaaguacua gguaugguac uaaacuauuc gcgaaguuua      480

gcagaagacu ucgcugaaca accaauaaaa gaugccguaa uaacaguccc agucuucuuu      540

aaccaagcag aaaggagagc cguucuacaa gcggcuagaa uggcaggauu aaaaguauug      600

caacuaauaa augacaauac ugcgaccgcc cuaaguuacg gcguuuuucg aagaaaagau      660

auaaauacaa cagcccaaaa cauaauguuc uacgacaugg gaaguggauc aacaguaugc      720

acuauaguua cauaccaaau gguaaaaacg aaggaagcag gaaugcaacc acagcuacaa      780

auaagaggag uaggauuuga ucguacacua ggaggauuag aaauggaacu aagacuuaga      840

gaacgcuuag caggauuguu caaugaacaa agaaagggcc aacgcgccaa ggaugugaga      900

gagaauccaa gagcaauggc aaaauuacuc agagaggcca accgguuaaa aacaguguua      960

ucagcaaacg cagaucauau ggcucagaua gaaggacuga uggaugacgu ugauuucaaa     1020

gcaaaaguca cacgaguuga auuugaagag uuaugugcag auuuauucga aagaguuccu     1080

ggaccuguuc aacaagcgcu acaaagugca gaaaugaguu uagaugagau ugaacaagug     1140

auucuaguug gcggagcaac ucgaguucca agaguccaag aaguacuguu aaaagccgua     1200

ggcaaagaag aauuagguaa aaauauaaau gccgaugaag cagccgcaau gggagccguu     1260

uaucaagcug cugccuuauc gaaagcauuu aaaguaaaac cauuuguugu aagggacgcc     1320

gugguauacc caauauuagu cgaguuuaca cgagaagucg aagaagaacc cggaauacau     1380

ucauuaaaac auaacaaacg aguucuauuu ucaagaaugg ggccguaucc acaaagaaaa     1440

guaauaaccu uuaauagaua cucccacgau uuuaauuucc acauuaauua uggagaucua     1500

ggauuuuuag guccggaaga ucuucgugua uuugggucac aaaauuugac aacagucaaa     1560

cuaaaaggag ucggagacuc auuuaagaaa uauccagauu augaaucaaa aggaauuaaa     1620

gcucauuuca auuuggauga aaguggagua cucagucuag auaggguaga aagcguauuu     1680

gaaacauuag ucgaagacuc agcagaagaa gaaagcacuc ugacuaaacu aggaaauaca     1740

auaucaucac uauucggagg ugggacgacc ccagaugcaa aagaaaaugg aacagauacu     1800

guacaggaag aagaagaauc accagcagaa ggaagcaagg augaaccagg ugagcaagua     1860

gaacuaaaag aagaagcaga agcaccagua gaagacggaa gucaaccacc uccaccagaa     1920

ccuaaaggag acgcgacccc agaaggagaa aaagcuacag aaaaggaaaa uggagauaaa     1980

ucagaagcuc aaaaaccguc agaaaaagcu gaagcaggac cagaaggcgu ugccccagca     2040

ccggagggag aaaagaaaca aaaaccagca agaaaaagaa gaauggugga agaaaucggu     2100

guagagcuag uaguauuaga cuuaccugac uuaccagaag auaaauuggc ucaauccguu     2160

caaaaacuuc aagaucuaac acuuagagac uuagaaaaac aagaacgaga aaaagcagca     2220

aacucacuag aagcauuuau auucgaaaca caggauaaac uauaccaacc agaauaccaa     2280

gagguuucaa cugaggaaca aagggaagag aucucaggaa aacucagugc agccaguaca     2340

ugguuggaag acgaaggagu aggcgcaaca acggucaugu uaaaagaaaa acuagcggaa     2400

cuuagaaaau uaugccaagg auuauuuuuc agaguugaag aaagaaagaa auggccagaa     2460

agauuauccg cuuuggauaa uuuauuaaau cauucaucaa uguuucuaaa aggcgcaaga     2520

uuaauaccug aaauggauca aauauucaca gaaguagaaa ugacuacauu agaaaaagua     2580

auaaaugaaa cuugggcuug gaaaaaugcu acacuagcag aacaagcaaa auuaccagcu     2640

accgaaaaac caguacuacu aucaaaagac auagaggcaa aaaugauggc ccuagacaga     2700

gaaguucaau aucuacuaaa uaaagcaaaa uuuacuaaac cuagaccaag accuaaagau     2760

aaaaauggua cacgagcuga gccuccacuc aaugcguccg cauccgauca aggagaaaaa     2820

guuauacccc cugccggaca aacagaagac gcagagccaa ucucagaacc agaaaaagug     2880

gaaacaggaa gugaaccugg agacacagaa ccacuagaac ucggaggucc gggggcagaa     2940

ccagaacaaa aagaacagag uacaggacaa aaacgaccgc uaaagaauga ugaguuauaa     3000


<210>  1247
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  1247
augccagagg aaacccaaac ucaagaucaa ccaauggaag aagaagaagu agaaacauuu       60

gcuuuccaag ccgaaauagc acaacugaug ucacuaauaa uaaauacauu uuauucaaac      120

aaggaaauuu ucuugagaga acucauaagu aacucaagcg acgcacucga caaaauaaga      180

uacgaaagcc uaacagaccc gucuaaacug gacucaggaa aagagcuaca uauaaaccua      240

auaccuaaca aacaagauag aacacuaacc auaguagaua caggaauagg uaugacaaaa      300

gcagauuuaa uaaacaaccu aggcacaaua gccaaguccg gaaccaaagc guucauggaa      360

gcgcuccaag ccggcgcaga uaucagcaug auaggacaau ucgggguagg auucuacuca      420

gcauaucuag uagcagaaaa aguaacgguu aucaccaaac auaaugacga cgaacaguac      480

gcaugggaaa guucggcagg cggcucauuc acagucagaa ccgacaccgg ggaaccaaug      540

ggaagaggua caaagguaau acuacaccuu aaagaagacc aaacagaaua ccuagaagaa      600

aggagaauaa aagaaauagu aaaaaaacac ucacaauuca uuggauaccc aauaacauua      660

uuuguagaaa aagaaagaga caaagaagua agcgacgaug aagcagaaga aaaagaagau      720

aaagaagaag agaaagaaaa agaagagaaa gaaagugaag acaaaccaga aauagaagac      780

guuggcucgg augaagaaga agaaaaaaaa gacggagaua aaaaaaaaaa aaaaaaaaua      840

aaagaaaagu acauagauca agaagaacuc aauaaaacaa agccaauaug gacacgaaau      900

ccagaugaca uaacuaacga agaauacggc gaauuuuaua aaaguuuaac aaacgacugg      960

gaagaccauc ucgcaguaaa acauuuuuca guagaaggac aacuagaauu cagagcacua     1020

uuauucgucc ccagaagagc accauuugau uuauuugaaa auagaaaaaa aaaaaacaac     1080

auuaaacuau auguaagaag aguuuucaua auggacaauu gugaagaauu aauaccagaa     1140

uaucuaaacu uuauaagagg ggugguugac agcgaagauu uaccgcuuaa cauaagccga     1200

gaaauguugc aacagaguaa aauacuaaaa guaauaagaa aaaaucuagu aaaaaaaugu     1260

uuagaauuau uuacggaauu agcagaggac aaagaaaacu acaagaaauu uuacgaacaa     1320

uucaguaaaa acauaaaauu aggcauacac gaagacaguc aaaauagaaa gaaacuauca     1380

gaacuacuaa gauauuacac aagugcaagu ggagaugaaa ugguaagcuu aaaagacuac     1440

uguacaagaa ugaaggaaaa ccaaaaacau auauauuaua uaacaggaga aacaaaagau     1500

caaguagcaa acagugccuu cguagaaaga cuaagaaaac augggcuaga aguaauauac     1560

augauagaac cuauagauga auauugcgua caacaacuaa aagaauuuga aggaaaaacc     1620

cuaguaucgg uaacaaagga aggauuagaa uuacccgaag augaagaaga aaaaaagaaa     1680

caagaagaaa aaaaaacaaa auucgaaaac cuaugcaaaa uaaugaaaga uauacuagaa     1740

aaaaaaguug aaaaaguugu gguaucuaac agauuaguaa cuucaccaug cugcaucgua     1800

acuaguacgu auggcuggac agcaaacaug gaaagaauaa ugaaagcaca ggcuuugaga     1860

gauaacagua ccaugggaua uauggcagca aaaaaacauc uagaaauuaa uccagaccac     1920

aguauaauag aaacguuaag acagaaagca gaagcggaca agaacgacaa aucaguaaaa     1980

gaccucguua uacuacucua ugaaacagca cuacuaagca guggauuuuc auuagaagau     2040

ccacagacac acgcaaacag gauuuauaga augauuaaac uuggacucgg aauagacgaa     2100

gaugacccaa cagcagauga cacaagugca gcagugaccg aagaaaugcc accguuagaa     2160

ggggaugacg acacuaguag aauggaagaa guagauuaa                            2199


<210>  1248
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  1248
auggacagcu caaaacuaga cucaggaaaa ggacuacaca uaaaccuagu accaaacaaa       60

caaaaccaaa cacuaacaau aguagacaca agaauaggaa ugacaaaaac agaccuaaua      120

aacaaccuag gaacaguaac aaaaagcgga acaaaagcau uuauggaagc acuacaagca      180

gacgcagaca uaagcaugau aggacacuuc ggaguaggau ucuacucagc auaccuagua      240

gcaaaaaaag uaacaguaau aucaaaacac aacaacgacg aacaauacac augggaauca      300

agcgcaggag gaagcuucac aguaagaaca gacgaauaa                             339


<210>  1249
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  1249
augccagaag aaguacacca uggagaagaa gagguagaaa cauucgcauu ucaagcagag       60

auugcacaac uaaugaguuu gauaauaaau acauuuuaua gcaacaaaga aauauuuuua      120

agagaacuaa uuucuaacgc aagcgacgca uuagacaaaa uacgauauga gagucuaacu      180

gauccaagua aacuagauag uggaaaggaa cuuaaaauag acauaauacc gaauccacaa      240

gaacgaacau ugacacuagu ggacacaggc auaggaauga caaaggccga ucuaauaaau      300

aaucuuggca caauagcaaa aagugggacu aaagcguuua uggaggcacu acaagcggga      360

gcagauauaa guaugauagg acaauuugga guuggauuuu auucagcaua cuuaguggca      420

gaaaaaguug ucguaauaac aaaacauaac gaugacgaac aauacgccug ggaaucaagc      480

gcaggaggaa guuuuacagu aagagcagac cacggugaac caaucggaag gggaacaaaa      540

guaauacuac acuuaaaaga agaucaaaca gaguauuugg aagaacgaag gguaaaagaa      600

guaguaaaaa aacacucaca auuuauagga uauccgauaa cauuguaccu agaaaaggaa      660

agggaaaaag aaauaagcga ugacgaagca gaagaagaaa aaggggaaaa ggaagaagaa      720

gauaaagacg augaagaaaa accaaaaaua gaggacguag gaagugauga agaagaugac      780

ucaggaaaag auaaaaaaaa aaaaacuaaa aaaaucaaag aaaaauacau agaucaagaa      840

gaauuaaaua aaacaaagcc aauauggacc agaaacccag acgacauaac acaagaagaa      900

uauggcgaau ucuauaaaag ucuaacaaau gacugggaag accaccuagc aguaaaacac      960

uucagcgucg aaggucaauu agaauucaga gcucuacuau uuauaccaag aagagcacca     1020

uucgaucuau ucgaaaacaa aaaaaaaaaa aauaauauaa aacucuacgu ccgcagaguc     1080

uuuauaaugg acucgugcga cgaacuaauc ccagaauauu uaaacuuuau cagaggggua     1140

guagacucag aggaccuccc acuaaacaua agcagggaaa ugcuucaaca aagcaaaauc     1200

cuaaagguaa ucagaaaaaa uaucgucaaa aaaugccucg aacuauuuuc agaauuagcc     1260

gaagauaaag aaaacuacaa aaaauuuuac gaagcauuca gcaaaaauuu aaaacuaggc     1320

auacacgaag acuccacaaa cagaagaaga uuaagcgaau uacuaagaua ucacacauca     1380

cagucgggag augaaaugac aucuuuauca gaguacguaa gccgaaugaa agaaacacaa     1440

aaaaguauau acuauaucac uggagaaagu aaagaacaag uagcgaacuc agcauuugua     1500

gaacguguaa gaaaacgagg auuugaagua guauacauga cagaaccaau ugacgaauac     1560

uguguccaac aauuaaaaga auucgauggu aaaaguuuag uuucaguaac aaaagaagga     1620

uuagaauuac cugaagacga agaagaaaag aaaaaaaugg aagaaagcaa agcaaaauuu     1680

gaaaaucuau gcaaacucau gaaagaaaua uuagacaaaa aaguggaaaa agucacgauu     1740

uccaacagac ucguaagcuc acccuguugc auaguaacau cuacauaugg uuggacugca     1800

aacauggaaa gaauaaugaa agcacaagcu uugagagaca auucaacaau gggauauaug     1860

auggcaaaga aacauuuaga aauaaaccca gaccauccaa ucguagaaac acugagacaa     1920

aaggcagaag cagacaaaaa ugauaaggcc gugaaagauc uugugguacu ucuauucgaa     1980

acagcccuac ugaguagugg auucaguuua gaagacccac aaacacacuc caauagaauc     2040

uaucgaauga ucaaacuagg auuaggaaua gacgaggaug aaguagcugc agaagaacca     2100

aaugcagcag uaccagauga aauaccaccg cuagaaggag augaagaugc gagccgcaug     2160

gaagaaguag acuag                                                      2175


<210>  1250
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  1250
augagagcac uguggguauu aggauuaugc ugcguauuac uaacguuugg aucagugaga       60

gcagaugaug aagucgaugu ugauggaaca guagaggaag accucgguaa aaguagagaa      120

ggcucaagaa cugacgacga aguuguucaa agagaagaag aagcgauaca auuagaugga      180

uuaaaugcau cacaaauaag agaacuucgu gaaaaaucag aaaaauuugc guuucaagca      240

gaaguaaaca gaaugaugaa acuaauaaua aauucauuau acaaaaauaa agaaauauuu      300

uuaagagaac uuauuucaaa cgcaagcgau gcauuggaua aaauaagauu gauaagucua      360

acagaugaaa acgccuuauc aggaaaugaa gaauuaacag uaaaaauaaa augcgauaaa      420

gagaaaaauu uacuacaugu aacugacacg ggaguaggaa ugacaagaga agaauuaguc      480

aaaaauuugg gaacaauagc caaaucagga accucagaau uucuaaacaa aaugacugaa      540

gcacaagaag acgggcaauc aacaagugaa uuaauaggac aauuuggggu aggauucuac      600

agugcguuuu uaguagcgga caagguaaua guaaccagua aacauaauaa cgacacacaa      660

cauauauggg agucagacag uaacgaguuc aguguaaucg cagacccgag agguaacaca      720

uugggacgag gaacaacuau aacguuagua cucaaagaag aggcuucaga uuaccuagaa      780

cuggauacaa uaaagaaucu cgugaagaaa uauucccaau ucaucaacuu cccaauauac      840

guauggaguu caaaaacaga aacaguggag gaaccaaugg aagaagaaga agcagcuaaa      900

gaagagaaag aagaaucaga ugaugaagcu gcagucgaag aagaagaaga agaaaagaaa      960

ccgaaaacua agaaaguaga gaaaacaguu ugggauuggg aacuaaugaa cgacauaaaa     1020

ccaauuuggc aacgaccguc aaaagaagug gaagaggaug aauauaaagc auuuuacaaa     1080

ucauucucua aagaaucaga ugauccaaug gcauauauac auuuuacagc agaaggggaa     1140

guaacauuua agucaauccu auuuguacca accucagcac cgaggggauu auucgacgaa     1200

uauggaagca agaaaucgga uuauauaaaa cuauauguaa gaaggguauu uauaaccgau     1260

gauuuccacg auaugaugcc caaauaucua aauuuuguaa aaggaguagu agacagcgac     1320

gaucuaccau uaaauguauc ucgagaaaca cuccaacagc auaaacuccu aaaaguuaua     1380

aggaagaaau uagucaggaa aacacucgau augauaaaga aaauagcaga ugauaaauau     1440

aacgacacau uuuggaaaga auuugguaca aauauuaaau uaggaguaau cgaagaucac     1500

aguaacagaa cgagauuagc aaaacuauug agauuucaaa guucacacca cccaacagau     1560

auaacuagcu uagaccaaua uguggaaagg augaaagaaa aacaagauaa aauuuauuuu     1620

auggcaggga guaguaggaa agaagcugaa aguagccccu ucguggaaag auuauuaaag     1680

aaaggauaug aaguaauaua ucuaacagaa ccaguagacg aauauuguau acaagcacua     1740

ccagaguucg acggaaaaag auuucaaaau guagccaaag aaggaguaaa auuugacgag     1800

ucagagaaaa caaaagaaag cagagaagca guagaaaaag aauuugaacc ucuacuuaac     1860

uggaugaaag auaaggcuuu aaaagauaaa auagaaaaag caguaguaag ccaaagacuu     1920

acagaaucac caugugcauu gguagcaagu caauauggau ggaguggaaa cauggaaagg     1980

auaaugaaag cacaagcgua ccaaacagga aaagauauau caacgaauua cuaugccagc     2040

cagaaaaaga cauucgaaau aaauccaaga cacccauuaa uaagagacau guuaagaaga     2100

auuaaagaag augaagauga uaaaacugua uuagaccuug caguaguuuu guucgaaacg     2160

gcaacauuac gaaguggcua ucugcuaccg gauacaaaag cauauggaga cagaauagaa     2220

cgaauguuaa gacuaucauu aaauauagau ccugaugcca aaguagaaga agaaccagaa     2280

gaagaaccag aagaaacggc agaagauaca acagaagaca ccgaacaaga cgaggaugag     2340

gaaauggacg uaggaacuga ugaagaagaa gaaacagcaa aagaaagcac ugcagaaaaa     2400

gaugaacuau aa                                                         2412


<210>  1251
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  1251
auggcaagag aacuaagagc auuacuauua uggggccgcc gacuaagacc ucucuuaaga       60

gcuccagcac uagcagccgu accaggcgga aagcccauac uauguccaag gagaacaacu      120

gcacaacuag gaccaagaag aaauccugcu uggagucugc aagcagguag gcuuuucucc      180

acacaaacag cugaagacaa agaagaaccc uuacauucaa uaauaucuag uacagaaucu      240

guucaaggaa guaccucaaa acaugaauuu caagcagaaa caaaaaaacu acuagacaua      300

guagcacgau cacuauauag ugaaaaagaa guuuuuauaa gagaauuaau aaguaacgcc      360

ucagaugcac uagaaaaauu acgacacaaa uuaguaagcg auggucaagc uuuaccagaa      420

auggaaauac auuuacaaac uaacgcugaa aaaggaacca uuacaauaca agauacaggu      480

auaggaauga cacaagaaga acuuguuagu aaucuaggaa caauagcucg aucaggauca      540

aaagcauucu uagacgcauu acaaaaccaa gcagaagcua gcucgaaaau aauuggucaa      600

uuuggaguag gauuuuauuc agcauucaug guugcagaca ggguagaagu auauucacgu      660

agcgcugcac caggaucauu agguuaccaa uggcuaucag acgguucagg cguuuucgaa      720

aucgcagaag caucaggagu aagaacagga acaaaaauaa uaauacaccu aaaaagugau      780

uguaaagagu ucucuaguga agcaagaguu agagauguag uaacaaaaua uucuaauuuu      840

guaucguuuc cacuauacuu aaauggacga agaaugaaua cacuacaagc aauauggaug      900

auggauccaa aagauguacg agaauggcaa caugaagaau ucuacagaua cguugcacaa      960

gcacaugaca aaccaagaua uaccuuacau uauaaaaccg acgcaccuuu aaauauaaga     1020

ucaaucuuuu auguuccaga caugaaaccc ucuauguucg acguaucaag agaacuagga     1080

aguagugugg cccuuuauuc aagaaaaguc cuaauucaaa caaaagcaac agauauauua     1140

ccuaaauggu ugagauuuau cagaggagua guagauucag aagacauccc auuaaaucua     1200

aguagggagc uauuacaaga aucagcauua auaaggaaac uaagagacgu uuuacaacaa     1260

agacuuauaa aauuuuuuau agaucaaagc aaaaaagaug cagaaaaaua cgcuaaauuu     1320

uucgaagacu augggcuauu uaugagagag ggaauaguaa cagcaacuga acaagaagua     1380

aaagaagaca uugcaaaacu acucagauau gaaaguagug cucugccuag cggucaauua     1440

acaagucugu cugaauaugc uucacgaaug agggccggaa caagaaauau auacuacuua     1500

ugcgcaccaa accgacacuu agcagaacau ucacccuauu augaggcaau gaaaaagaaa     1560

gacacagaag uucuauuuug cuuugaacaa uucgacgaac ucacuuuacu acaccuaaga     1620

gaauuugaca aaaaaaaauu aauuagcguc gaaacagaua uagugguuga ccauuauaaa     1680

gaagaaaaau uugaggauag aucuccagcg gccgaaugcc uuucagaaaa agaaacagaa     1740

gaacuuaugg ccuggaugag aaacguucua gggucuagag uaacaaaugu gaaaguaaca     1800

uuaagauuag acacacaucc ggcaauggua acaguucuag aaaugggagc ggcaagacac     1860

uuuuuaagaa ugcaacaauu ggcaaaaaca caggaagaaa gagcacaauu auuacagcca     1920

acacucgaaa ucaacccuag acacgcauua auaaaaaaac uaaaucaacu aagagcauca     1980

gaaccaggac uugcacaauu gcuagucgau caaauauacg aaaaugcaau gauagcagca     2040

ggauuaguag augauccacg agcgauggua ggacgacuaa augaguuauu aguaaaagca     2100

uuagaaagac acuaa                                                      2115


<210>  1252
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  1252
augggaaaaa uaucaucacu accaacacaa cuauucaaau gcugcuucug cgacuuccua       60

aaaguaaaaa ugcacacaau gucaucauca caccuauucu accuagcacu augcuuauua      120

acauucacau caucagcaac agcaggacca gaaacacuau gcggagcaga acuaguagac      180

gcacuacaau ucguaugcgg agacagagga uucuacuuca acaaaccaac aggauacgga      240

ucaucaucaa gaagagcacc acaaacagga auaguagacg aaugcugcuu cagaucaugc      300

gaccuaagaa gauuagaaau guacugcgca ccacuaaaac cagcaaaauc agcaagauca      360

guaagagcac aaagacacac agacaugcca aaaacacaaa aagaaguaca ccuaaaaaac      420

gcaucacgag gaucagcagg aaacaaaaac uacagaaugu aa                         462


<210>  1253
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  1253
augggaauac caaugggaaa aucaaugcua guacuacuaa cauuucuagc auucgcauca       60

ugcuguauag cagcauacag accaucagaa acacuaugcg gaggagaauu aguagauacc      120

uuacaauuug uauguggaga cagaggauuc uauuucucaa gaccagcauc aagaguauca      180

agaagaucaa gaggaauagu agaagaaugc uguuucagau caugugacuu agcauuacua      240

gaaacauauu gcgcaacacc agcaaaauca gaacgagaug uaucaacacc accaacagua      300

cuaccagaua acuuuccaag auacccagua ggaaaauuuu uccaauacga uacauggaaa      360

caaucaacac aaagacuaag aagaggacua ccagcacuac uaagagcaag aagaggacac      420

guacuagcaa aagaacuaga agcauuuaga gaagcaaaaa gacauagacc acuaauugca      480

uuaccaacac aagauccagc acacggagga gcaccaccag aaauggcauc aaacagaaaa      540

uaa                                                                    543


<210>  1254
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  1254
augaacucau ucucaacauc agcauucgga ccaguagcau ucucacuagg acuacuacua       60

guacuaccag ccgcauuccc agcaccagua ccaccaggag aagacucaaa agacguugca      120

gcaccacaca gacaaccccu aacauccuca gaaagaauag acaaacaaau aagauacaua      180

cuagacggaa uaucagcacu aagaaaagaa acaugcaaca aaucaaacau gugcgaauca      240

ucaaaagaag cacuagccga aaacaaccua aaccuaccaa aaauggcaga aaaagacgga      300

ugcuuccaau cagguuucaa cgaagaaaca ugccuaguaa aaauaauaac aggacuccua      360

gaauucgaag uauaccuaga auaccuacaa aacagauucg aaucaucaga agaacaagca      420

agagcaguac aaaugucaac uaaaguacua auacaauucc uacaaaaaaa agcaaaaaac      480

cuagacgcaa uaacaacacc agacccaaca accaacgcau cacuacucac aaaacuacaa      540

gcacaaaacc aauggcuaca agacaugaca acacaccuua uacuacgauc auucaaagaa      600

uuccuccaau caucccuccg agcccucaga caaauguaa                             639


<210>  1255
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  1255
augccauuac uaugguuaag aggauuuuua uuagcuaguu gcuggauaau agucagauca       60

agcccaacgc caggaagcga aggacacuca gcagcuccag acuguccaag uugugcauua      120

gcagcauuac cuaaagaugu uccuaauuca caaccagaaa ugguagaagc aguaaaaaaa      180

cauauauuaa auauguuaca cuuaaaaaaa aggccagacg uaacacaacc aguuccaaaa      240

gcagcauuau ugaacgcaau aagaaaauua cacguaggaa agguagggga aaacggauau      300

guagaaauag aagacgauau aggaagaaga gcagaaauga augaacuaau ggaacaaaca      360

agugaaauaa uaacuuucgc agaaagcgga acagcaagaa aaacacuaca cuuugaaaua      420

aguaaagaag ggagcgauuu aucaguagua gaaagagcag aaguaugguu auuucuaaaa      480

guaccaaaag caaauagaac uagaacaaaa guaacaauaa gacuauucca acaacaaaaa      540

cauccacaag gaucuuuaga uacuggagaa gaagcggaag aaguaggacu uaaaggagaa      600

agaucagaac uacuauuaag ugaaaaagua guagaugcac gaaaaaguac auggcaugua      660

uuuccaguau ccaguucaau acaaagacua uuagaucaag gaaaaagcag cuuagacguu      720

agaauagcuu gugaacagug ucaagaauca ggagcaaguu uaguuuuacu aggaaaaaaa      780

aaaaaaaaag aagaagaggg agaagguaaa aaaaaaggug ggggagaagg aggagcagga      840

gcugaugaag aaaaagaaca aucacauaga cccuucuuaa ugcuacaagc aagacaauca      900

gaagaucauc cacauagaag aagacgaaga ggcuuagaau gugauggaaa aguaaauaua      960

uguugcaaaa aacaauucuu uguaucauuu aaagauauag gauggaauga uuggauaauu     1020

gcacccagcg guuaucaugc aaacuauugu gaaggagaau gcccaucaca cauagcggga     1080

acuaguggaa guucauuaag cuuucacuca acugugauaa aucauuaucg uaugagaggc     1140

cauucgccgu uugcaaauuu aaaaucaugu uguguaccaa caaaacuaag accaaugagu     1200

auguuauauu augacgaugg acaaaauaua auaaagaaag acauacaaaa uaugauagua     1260

gaagaaugug gauguaguua a                                               1281


<210>  1256
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  1256
auggacggau uaccuggcag agcuuuggga gcagcauguc uauuacuauu agcugcagga       60

ugguuaggac cagaagcaug gggaucgcca acaccaccac caacaccagc ugcaccacca      120

ccaccaccac cuccugguuc accaggcggg ucucaagaca ccuguacaag cuguggaggc      180

uuuaggaggc cagaagaacu aggaagagua gauggagacu uuuuagaagc uguaaaaaga      240

cauauacuua guagacucca aaugagagga agaccaaaua uaacacaugc cguaccaaaa      300

gcugcaaugg uaacugcacu ucgaaaacua caugcaggaa aaguaagaga agauggaagg      360

guagaaauac cucaucuaga uggacaugca ucaccaggag cagauggaca agaaagagua      420

ucagaaauaa uaucuuuugc agaaacagau ggauuagcgu caucaagagu aagauuauac      480

uuuuucauau caaacgaagg aaaucaaaau uuauuuguag uacaagcgag cuuaugguua      540

uaucuaaaau uauuacccua uguuuuagaa aaaggaucaa gacgaaaagu aagaguaaaa      600

guuuauuuuc aggaacaagg acacggagac agauggaaua ugguagaaaa gagaguagac      660

uuaaaaagaa guggauggca uacauuccca cuaacugaag caauucaagc acuauuugaa      720

agaggagaaa gaagauuaaa ccuagaugug caaugugauu cuugucaaga auuagcaguc      780

guaccaguau uuguugaucc aggagaagaa agucauagac cauuuguggu aguucaagca      840

agauuaggag auaguagaca uaggauaaga aaaagaggau uagaauguga uggaaggaca      900

aauuuauguu guagacaaca auucuuuauu gacuuuagau uaauaggaug gaaugauugg      960

auaauagcac ccacaggaua uuaugggaau uauugugaag gaaguugucc agcauacuua     1020

gcaggaguac ccggaucagc aaguuccuuu cauacagcag uugucaacca auaucgaaug     1080

agaggguuaa auccagguac aguaaacuca uguuguauac caaccaaacu aaguacuaug     1140

agcauguuau auuuugauga ugaauauaac auuguaaaac gagauguacc aaacaugaua     1200

guagaagaau guggaugugc auaa                                            1224


<210>  1257
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  1257
auggcauuaa gaguauuacu gcugacagcu uugacucuau gucacggcuu caaccuagac       60

acagaaaaug cuaugaccuu ucaagaaaau gcacgagguu ucggacaguc ugucguccaa      120

cuacaaggau caaggguugu agucggcgca ccccaagaaa uuguagcagc aaaucaaaga      180

ggcuccuuau aucaaugcga cuacucaaca gguagcugcg aaccaauacg ucuucaaguu      240

cccguugaag cagugaacau gucacuuggu uuaaguuuag cagcuacaac aagcccaccu      300

caacuauuag cuugcggccc cacaguacac caaaccugua gcgaaaauac uuauguuaaa      360

ggauuguguu uccuauucgg uuccaauuua cgacagcaac cucaaaaauu cccugaagca      420

cuucguggau gcccccaaga agauagcgau auagcauuuu uaaucgacgg uuccggaucc      480

auaauacccc augacuuccg gagaaugaaa gaauuuguaa guacagugau ggaacaauug      540

aagaaaucua aaacucuauu uucucugaug caauauagug aagaauuuag gauacacuuu      600

acuuuuaaag aauuucaaaa caacccaaau ccgagaucgu uaguaaaacc gauuacucag      660

cuuuuaggac gaacucauac agcuacugga auacguaaag uaguaagaga acucuucaac      720

auaacaaaug gcgcacguaa aaaugcuuuu aagauauuag uaguaauuac agacggagaa      780

aaauucggag auccucuagg auacgaagac guaauaccag aagcugauag agagggcgua      840

auaagauaug uaauaggcgu uggagaugca uucagaagcg agaaaagcag acaagaauug      900

aacacaaucg caucuaaacc cccacgagau cauguauucc aggucaauaa uuucgaagcu      960

cuaaaaacaa uacaaaacca acugagagag aaaauauuug caauagaagg gacacaaaca     1020

ggcucaucga gcucauuuga acaugaaaug agccaagaag gauuuucagc agcaauaacc     1080

ucaaacggac cacuauuauc cacuguugga aguuaugauu gggcaggggg agucuucuua     1140

uacacgucca aagaaaaauc uacauuuaua aacaugacca gaguugacag ugacaugaau     1200

gacgcuuacc ucggcuaugc agcagcuauu auacuacgaa auagaguaca aucacuuguu     1260

uuaggggcac cacgguacca acauauuggu cuaguugcca uguuccgaca aaauacagga     1320

augugggaau caaaugccaa uguaaaagga acacaaauag gagcuuauuu cggcgcauca     1380

uuauguuccg uagauguaga cucaaacgga ucaacagauu uaguccugau uggugcccca     1440

cauuauuaug aacaaacaag agguggucag guaaguguuu guccgcuccc acgagguaga     1500

gcccgauggc aaugcgaugc uguacuuuau ggagaacaag gacagccaug gggaagauuc     1560

ggggcagcac uaacaguacu aggugacgug aauggggaua aacuaaccga uguagcaaua     1620

ggugcaccag gcgaagaaga caauagagga gcaguauacu uauuucacgg aacaucaggc     1680

ucaggaauaa gcccuucgca cucacaaaga aucgcuggca guaaauuaag cccucgccuu     1740

caauacuuug gacagucgcu uaguggaggc caagaucuaa caauggacgg auuaguugac     1800

cuaacgguag gagcacaggg ucauguccua cuauuacgau cccaaccugu uuugcguguc     1860

aaagcaauua uggaguucaa uccaagagaa guagcacgaa auguuuuuga augcaaugau     1920

caaguaguua aaggcaaaga agcuggagaa guacggguuu gucuacaugu acaaaaaucc     1980

acacgagacc gucuacgcga aggucaaaua caaucaguag uuaccuauga ucuugcacuu     2040

gacucuggaa gaccucacuc uagggcugua uuuaaugaaa cuaaaaauuc cacgagacga     2100

caaacacaag uacuaggucu uacccaaacu ugugaaaccu uaaagcuaca acucccaaau     2160

ugcauagaag auccaguaag uccaauagua cugagacuca auuucucccu ugucggaacc     2220

ccucuaagcg cguucggaaa cuuacgacca guacuagcag aagacgcaca gagacuuuuu     2280

acugcacuuu uuccauucga gaaaaauugc ggaaacgaca auauauguca agacgacuua     2340

ucuauaacau uuucauucau gucauuagau uguuugguag uuggaggucc ccgggaguuc     2400

aaugucacag uaacagucag aaaugaugga gaagauucuu accgaacaca aguuaccuuu     2460

uucuuuccac uugauuuaag cuaccgaaaa gucucuacac uacagaacca acgaagucaa     2520

cgcucgugga gacuugcaug ugaaagcgcu ucuucaacug aaguuucagg ugcuuugaaa     2580

ucaacaucau guaguauaaa ccaucccauu uuuccggaaa auucugaagu uacauuuaac     2640

auuacguucg augucgauuc aaaggcuucu cuugguaaua aauuacuauu gaaagcaaau     2700

gucacauccg aaaauaauau gccaaggacc aacaaaacag aguuccaacu ugaauuaccu     2760

guaaaauaug cugucuacau gguuguaaca ucacauggag uaucuaccaa auaucucaau     2820

uuuacagcau cugaaaauac uucacgagua augcaacacc aauaccaagu aucaaauuua     2880

ggacaacgau cacucccaau uagucuuguu uuucuagucc cagucagauu gaaucaaaca     2940

guaaucuggg auagaccaca aguaacauuu ucugaaaacu uaagcaguac augucauaca     3000

aaagaacgcu uaccauccca uuccgacuuu cuugcugaau uaagaaaagc accugucguc     3060

aauugcucaa ucgcagugug ccaacgaaua caaugugaca uucccuucuu uggcauacaa     3120

gaagaguuua acgcuacacu aaagggcaau uuauccuuug acugguacau aaaaacauca     3180

cauaaucauc uauuaauugu aucaacagca gaaauauuau uuaacgacag cguauucaca     3240

cuucuccccg ggcaaggagc uuuugucaga agucaaacag aaacaaaagu agaaccauuc     3300

gaaguuccaa accccuuacc ucucauagua gguuccucgg uagguggauu acuacugcuu     3360

gcauuaauua cagccgcuuu auauaaacuu ggauucuuua agagacaaua uaaggauaug     3420

augucugaag gaggaccucc uggcgcagaa ccacaauaa                            3459


<210>  1258
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  1258
auguucucac uuaaaacucu cccauucuua cuacuacuac acguccaaau aucaaaagcc       60

uuccccguau ccucaaaaga aaaaaauacu aaaacaguuc aagacuaccu cgaaaaauuc      120

uaccaacuac cuucaaacca auaccaauca acaagaaaaa augguacuaa ugucauaguc      180

gaaaaauuaa aagaaaugca aagauuuuuu ggacuuaacg uuacaggaaa accuaacgaa      240

gaaacccuag acaugaugaa aaaaccacga ugcggagucc cagacucagg aggcuucaug      300

cuaacaccag gaaauccaaa augggaacgu acaaacuuaa cauaccgcau acgaaacuac      360

accccacaac uaagugaagc agaaguagaa cgcgccauaa aagacgccuu cgaacuaugg      420

ucaguagcaa gcccacucau auuuacuaga auaucacaag gugaagcuga uaucaauauc      480

gcauuuuacc aacgagacca cggcgauaac ucaccauucg acggcccaaa uggaauacua      540

gcccacgcau uccaaccagg acaaggaaua ggaggugacg cacacuucga cgcagaagaa      600

accuggacaa acacaucagc aaacuauaac uuauuucuag ucgccgcaca cgaauucgga      660

cacucacuag guuuagcaca cucaucagac ccaggcgcac uaauguaucc caacuaugca      720

uucagagaaa ccucaaauua uucauuaccu caagacgaua uagacggaau ucaagcaaua      780

uauggacuuu cuucaaaucc aauacaacca acaggcccuu caaccccaaa acccugugau      840

cccucacuaa cauucgacgc aaucacaacu cuacgaggag aaauuuuauu cuuuaaagac      900

agauauuuuu ggagaagaca cccacaacua caaagaguag aaaugaacuu cauaagcuua      960

uucuggccau cacuaccaac aggcauucaa gcagcauacg aagacuucga uagagaccua     1020

auauucuuau uuaaaggaaa ccaauauugg gcacuaucag guuacgacau acuacaagga     1080

uacccaaaag acauauccaa uuauggauuc ccaucaucag uacaagcaau agacgcagca     1140

guauucuaua gaucaaaaac cuacuucuuc guaaaugauc aauucuggag auacgacaac     1200

caacgccaau ucauggaacc cggauauccc aaaucaauau caggagcauu cccaggaaua     1260

gaaucaaaag uagacgcugu auuccaacaa gaacauuucu uucaugucuu cuccggaccc     1320

agguacuacg cauuugauuu aauagcccaa agaguaacac gaguagcaag aggaaauaaa     1380

ugguugaauu guagauacgg auaa                                            1404


<210>  1259
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  1259
augagccuuu ggcaacccuu aguuuuaguu uuacuaguau uaggaugcug cuucgcagcu       60

ccuagacaaa ggcaaucaac acuuguucuc uuuccaggag acuuacgaac aaaucuaaca      120

gauagacaac uagcagaaga auacuuauau agauauggau auaccagagu ugcagaaaug      180

agaggagaaa guaaaucguu aggaccugcc cuacuacuuc uucaaaaaca auuaucauua      240

ccagaaacag gagaacuaga uucugcuaca cuaaaagcaa ugagaacccc uagaugcgga      300

guuccagauu uaggccgauu ucaaacauuu gaaggagacc uaaaauggca ccaucauaau      360

auaacuuauu ggauacaaaa uuacucugaa gacuuaccga gagccguaau agacgaugca      420

uucgcuagag cauuugcuuu auggucagca guuacacccc uaacauuuac uagaguauau      480

ucaagagaug cugauauagu aauucaauuu ggagucgcag aacaugguga uggauaucca      540

uuugauggaa aagacggauu auuagcccac gcauucccac cugguccagg cauucaagga      600

gaugcacauu ucgacgauga cgaauuaugg agcuuaggaa aaggaguagu aguaccuaca      660

cgcuuuggga augcugaugg agcagcaugc cauuucccau uuauuuucga agguagauca      720

uacucugcau gcacuacaga uggaagaucc gauggauuac cuuggugcag cacaacagcu      780

aauuaugaca cugaugacag auuugguuuu uguccauccg aaagacuuua cacacaagac      840

ggaaaugcag augguaaacc augccaauuu ccuuuuauau uucagggaca aucauauuca      900

gcuuguacaa cagaugggag aagugaugga uaccgcuggu gugcaaccac ugccaauuau      960

gauagagaca agcuauuugg auucuguccu acaagagcag acucgacugu aaugggugga     1020

aauucagccg gagaacuaug ugucuuccca uuuacauuuu uagguaaaga auacucuaca     1080

uguacuucag aaggccgugg ugauggaaga cuuuggugug caacaacauc aaauuucgac     1140

ucugacaaaa aauggggauu uuguccagau caaggauaca gcuuauuucu aguugcagca     1200

cacgaauuug gacaugcacu agguuuagau cacaguucag uaccagaagc auuaauguau     1260

ccaauguaua gauuuaccga agggccuccc cuucacaaag augacguuaa uggaauaaga     1320

cacuuauacg gacccagacc ugaaccugaa ccaagaccuc cuacuacaac uacuccacaa     1380

ccaacagccc caccaacagu augcccaacg ggaccgccaa caguacaccc aagcgaaaga     1440

ccaacugcug gaccaacagg accacccagu gcagguccaa cugguccacc uacagcaggc     1500

ccaucuacug caacaacagu cccauuaagu ccaguggacg augcaugcaa cguuaacaua     1560

uucgacgcaa uugcagaaau uggaaaucaa uuauaucuuu uuaaagaugg aaaauacugg     1620

agguucucag aaggaagagg uucaagacca caagguccau uucuuauagc ugauaaaugg     1680

ccagcucucc ccagaaaauu agacucagua uucgaagaac gauuaaguaa aaaauuauuc     1740

uucuuuucag gcagacaagu uuggguauau acuggugcaa guguacucgg accaagaaga     1800

cuugauaaau uaggcuuagg ggcagacguu gcacaaguaa cuggagcccu aagauccggu     1860

cgaggaaaaa uguuauuauu cucaggaaga agauuaugga gauuugaugu uaaagcacaa     1920

augguugauc caagaucagc aucagaagua gacagaaugu uuccaggcgu accacuagau     1980

acucaugacg uauuucaaua ucgggaaaaa gcguacuuuu gucaagauag auuuuauugg     2040

agaguuucuu caagaucaga auuaaaccaa guagaucaag uuggauaugu aacauaugau     2100

auccuacaau gcccagaaga cuaa                                            2124


<210>  1260
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  1260
augcacccag gaguacuagc agcauucuua uucuuaucuu ggacccacug uagagcacua       60

ccucuaccua gcggaggaga ugaagaugac cucucagaag aagaccuaca auucgcagaa      120

agauaucuac gaucuuauua ccacccaaca aacuuagcag gaauacuaaa agaaaacgcu      180

gcaucaucaa ugacagaaag acuaagagaa augcaaucau uuuucggacu agaaguaaca      240

ggaaaauuag acgacaacac auuagacgua augaaaaaac caagaugcgg aguaccagau      300

gucggagaau acaacgucuu cccaagaaca uuaaaaugga gcaaaaugaa ccuaacauau      360

agaauaguaa auuacacacc cgacaugaca cacucagaag uagaaaaagc auuuaaaaaa      420

gcauucaaag uaugguccga ugucacaccc cuaaacuuca caagauuaca ugacggaaua      480

gcagacauaa ugauaucuuu cggaauaaaa gaacacggug acuucuaccc uuucgacgga      540

ccaucaggac uauuagcaca cgcauuccca cccggaccaa auuacggagg agaugcacac      600

uuugacgaug augaaacuug gacaucauca ucaaaagguu auaacuuauu ucucguagcu      660

gcccacgaau ucggacacuc acuagggcua gaccacagca aagaccccgg agcauuaaug      720

uuuccaauuu auacauauac aggaaaaagu cacuuuaugc uaccggacga cgacguacaa      780

ggcauacaau cacucuacgg uccaggagac gaagacccaa acccaaaaca ccccaaaaca      840

ccagauaaau gcgacccauc acuaucauua gaugcaauaa caucauuaag aggagaaacu      900

augauuuuca aagacagauu cuucuggagg uuacaccccc aacaaguaga ugcagaacuc      960

uuucuaacaa aaucauuuug gccagaauua ccaaauagaa uugacgcugc auacgaacac     1020

ccaucacacg accuaauauu uauauucaga ggaagaaaau ucugggccuu aaacggauau     1080

gacauacuag aaggauaccc aaaaaaaaua ucagaauuag gucuacccaa agaaguaaaa     1140

aaaauaucag cagccgucca cuucgaagac acuggaaaaa cauuacucuu uaguggcaac     1200

caaguaugga gauaugacga uacaaaccac auaauggaua aagacuaccc aagauuaaua     1260

gaagaagacu uuccaggaau uggagacaaa guagacgccg uauacgaaaa aaauggauac     1320

auauacuuuu ucaacggacc aauucaauuc gaauauucca uauggucaaa ccgaauaguu     1380

aggguaaugc cagcaaacuc cauauuaugg uguuaa                               1416


<210>  1261
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  1261
auggaaacac caaauacaac agaagacuau gacacaacua cagaauucga cuauggcgac       60

gccacaccau gccaaaaagu aaacgaaaga gcauucggcg cacaauuauu accaccuuua      120

uacucauuag uauucguaau aggauuagua ggaaacauac uaguaguauu aguacuagua      180

caauacaaaa gacuaaaaaa caugacaucc auauaccuac uaaacuuagc aauaucugac      240

cuacuauucc uauucacucu accauucugg aucgacuaua aacuaaaaga ugacuggguu      300

uucggugacg caaugugcaa aauccucuca ggauuuuacu acacaggauu auacagcgaa      360

aucuuuuuca ucauacuauu aaccaucgac cgauaccuag ccauaguaca cgcaguauuc      420

gcacucagag ccagaacagu aacuuucggc guaauaacau caauaauaau cugggcauua      480

gccauacucg caucaaugcc aggacuauac uucucaaaaa cacaauggga auucacccau      540

cacacaugcu cauuacacuu cccucacgaa uccuuaagag aauggaaacu auuucaagcc      600

cuaaaauuaa acuuauucgg acuaguacua ccuuuacuag uaaugauaau cuguuacaca      660

ggaauuauaa aaauacuacu cagaagaccc aacgaaaaaa aaucaaaagc cguaagauua      720

auauucguaa uaaugauaau uuucuucuua uucuggacac cauacaacuu aacaauacuc      780

auuuccgucu uccaagacuu cuuauucacu cacgaaugcg aacaaucaag acaucuagac      840

cuagcagucc aagucaccga aguaauagca uacacacacu gcugcguaaa cccaguaauu      900

uacgcauucg uaggagaacg auucagaaaa uaccuuagac aacuuuuuca cagaagagua      960

gcaguccacc uugucaaaug gcuaccauuu uuaucuguag acagacuaga aagaguaucu     1020

ucaacaucac caucuacagg agaacacgaa cucucugccg gcuuuuaa                  1068


<210>  1262
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  1262
augcgaacac uagccugccu auuacuacua ggaugcggau accuagcaca cguacuagca       60

gaagaagcag aaauaccaag agaaguaaua gaaagacuag caagaucaca aauacacagu      120

auaagagacc uacaaagacu acuagaaaua gacucaguag gaucagaaga cucacuagac      180

acaucacuaa gagcacacgg cguacaugca acaaaacacg uacccgaaaa aagaccauua      240

ccaauaagaa gaaaaagaag cauagaagaa gccguaccag caguauguaa aacaagaaca      300

guaauauacg aaauaccaag aagccaagua gacccaacau cagccaacuu cuuaauaugg      360

ccaccaugcg uagaaguaaa aagaugcaca ggaugcugca acacaagcag cgucaaaugc      420

caaccaagua gaguacacca ucgaucagua aaaguagcaa aaguagaaua cgucagaaaa      480

aaaccaaaac uaaaagaagu acaaguaaga cucgaagaac accuagaaug cgcaugcgcc      540

acaacaagcc uaaacccaga cuacagagaa gaagacacag gaagaccaag agaaucagga      600

aaaaaacgaa aaagaaaaag acuaaaacca acuuaa                                636


<210>  1263
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  1263
augaacagau gcugggcacu auuccuauca uuaugcuguu acuuaagacu aguaucagca       60

gaaggagauc caauaccaga agaauuauac gaaauguuaa gugaucacuc aauaagaagc      120

uuugacgauu uacaaagacu acuacaugga gauccaggag aagaagacgg agcagaacuu      180

gaucuaaaua ugacaagauc acacagugga ggagaauuag aaucacuagc cagaggaaga      240

agaagucuag gaucacucac aaucgcagaa ccagcaauga uagcagaaug uaaaacaaga      300

acagaagucu ucgaaaucuc aagacgacua auagacagaa caaaugcaaa cuucuuagua      360

uggccaccau gcguagaagu acaaagaugc ucaggaugcu gcaauaacag gaacguacaa      420

uguagaccaa cacaaguaca acuaagaccc gugcaaguaa gaaaaauaga aauaguaaga      480

aaaaaaccaa ucuuuaaaaa agcaacagua acacuagaag aucaucuagc augcaaaugc      540

gaaacaguag cagcugcaag accaguaaca agaucaccag gaggaagcca agaacaaaga      600

gcaaaaacgc cacaaacaag aguaacaaua agaacaguua gaguaagaag accaccaaaa      660

ggaaaacaua gaaaauucaa acacacacac gauaaaacag cauuaaaaga aacauuagga      720

gcauaa                                                                 726


<210>  1264
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  1264
augucauuau ucggauuauu acuuuuaaca ucugcauuag caggacaaag acaaggaaca       60

caagcagaau caaaccuauc aagcaaauuu caauuuucau caaauaaaga acaaaauggc      120

guacaagauc cacaacacga aagaauaaua acaguaagca cuaacggauc aauacacagc      180

ccccgauucc cacauacaua cccaagaaac acaguauuag uauggagauu agucgccgua      240

gaagaaaaug uauggauaca acuuacauuc gaugaaagau ucggauuaga agaccccgaa      300

gacgacauau gcaaauacga cuucguagaa guagaagaac ccucagacgg aacaauauua      360

ggucguuggu gcggaucagg aacaguacca ggaaaacaaa uaaguaaagg aaaccaaaua      420

agaauucgau ucguaucaga ugaauacuuu ccaucagaac caggauucug cauccauuac      480

aauauaguaa ugccacaauu uacagaagca guaucaccaa gcguauuacc accaucagcc      540

cuaccucuag acuuauuaaa uaacgcaaua acagcauuua gcaccuuaga agacuuaaua      600

cgauacuuag aaccagaacg auggcaacua gaccuugaag accuauacag accaacaugg      660

caauuacuag gaaaagcauu cgucuuuggc agaaaaucaa gaguaguaga ucuaaaccua      720

cuaacagaag aaguaagauu auacaguugc acaccuagaa acuucucagu aagcauaaga      780

gaagaacuaa aaagaacaga caccauauuc uggccaggau gccuacuagu uaaaagaugc      840

ggaggaaauu gcgcauguug cuuacacaac uguaacgaau gccaaugcgu acccucaaaa      900

guaacaaaaa aauaccacga aguacuacaa uuaagaccaa aaacaggagu aagaggacuc      960

cacaaaucac uuacagacgu agcacuagaa caccacgaag aaugugacug cguaugcaga     1020

ggcucaaccg gaggauaa                                                   1038


<210>  1265
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  1265
augcauagau uaauauucgu auacacacua auaugugcaa acuucugcuc augcagagac       60

accagugcaa caccccaaag cgcaucaaua aaagcacuac gaaacgcaaa cuuaagaaga      120

gacgaucuau auagaagaga ugaaacaaua caaguaaaag gaaacggaua cguacaauca      180

ccacgauuuc caaauucaua cccacgaaac cuauuauuaa cauggcgacu acacucacaa      240

gaaaauacaa gaauacaacu ugucuucgac aaccaauucg gacuagaaga agcagaaaau      300

gacauaugca gauaugacuu cguagaagua gaagacauau cagaaacuuc aacaauaaua      360

agaggaagau gguguggaca caaagaaguc ccaccaagaa uaaaaucaag aacaaaccaa      420

auaaaaauaa ccuucaaauc agaugacuac uucguagcaa aaccgggcuu uaaaauauac      480

uauagccuau uagaagacuu ccaaccagca gcagcaucag aaaccaacug ggaaucagua      540

acaagcucaa uaucuggagu aucauacaac ucaccaucag uaacagaucc aacacuaaua      600

gcagacgcau uagacaaaaa aauagccgaa uucgacacag uagaagaucu acuaaaauac      660

uucaacccag aaucauggca agaagaccua gaaaacaugu accuagacac accaagauac      720

agaggaagau cauaccauga cagaaaaagu aaaguagacc uagacagacu aaacgacgau      780

gcaaaaagau acagcugcac accaagaaau uacucaguaa acauaagaga agaacuaaaa      840

cuagcaaacg uaguauucuu cccaagaugc uuauuaguac aaaggugcgg aggaaauugu      900

ggaugcggaa caguaaacug gagauccugu acaugcaacu caggcaaaac agucaaaaaa      960

uaccacgaag uacuacaauu cgaaccagga cacauaaaaa gaagaggcag agcaaaaaca     1020

auggcacuag uagacauaca acucgaucac cacgaaagau gcgacuguau augcucaagc     1080

agaccaccac gauaa                                                      1095


<210>  1266
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  1266
augguaacac acucaaaauu cccagcagca ggaaugucac gaccucuaga cacaucauua       60

cgacuaaaaa cauucucauc aaaaucugaa uaccaacuag uaguaaacgc aguaagaaaa      120

uuacaagaau caggauucua cuggucagca guaacaggag gagaagcaaa ccuacuauua      180

ucagcagaac cagcaggaac auuccuaaua agagacucau cagaccaaag acacuucuuu      240

acacuaucag uaaaaaccca aucuggaaca aaaaaccuac gaauacaaug ugaaggagga      300

uccuucucuc uacaaucaga cccaagauca acacaaccag uacccagauu ugacugcgua      360

cuaaaauuag uacaccacua caugccccca cccggagcac caucauuccc aucaccccca      420

acagaacccu caucagaagu accagaacaa ccaucagcac aaccacuacc aggcucacca      480

ccaagaagag cuuauuacau auacuccgga ggagaaaaaa uaccacuagu ucuaucaaga      540

cccuuaucau caaacguagc cacacuacaa caccuaugca gaaaaacagu aaacggacac      600

uuagacucau acgaaaaagu aacacaacuu ccaggaccaa uaagagaauu cuuagaucaa      660

uacgacgcac cauuauaa                                                    678


<210>  1267
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  1267
augguaccau cagcaggaca auuagcauua uucgcauuag gaauaguauu agcagcaugu       60

caagcauuag aaaauucaac aucaccauua ucagcagacc caccaguagc agcagcagua      120

guaucacauu uuaaugauug cccagauuca cauacacaau ucugcuuuca uggaacaugu      180

agauuuuuag uacaagaaga uaaaccagca uguguauguc auucaggaua uguaggagca      240

agaugugaac augcagauuu auuagccgua guagcagcau cacaaaaaaa acaagcaaua      300

acagcauuag uaguaguaag uauaguagca uuagcagucu uaauaauaac auguguauua      360

auacauuguu gucaaguaag aaaacauugu gaauggugca gagcauuaau auguagacau      420

gaaaaaccau cagcacuauu aaaaggaaga acagcauguu gucacucaga aacaguagua      480

uaa                                                                    483


<210>  1268
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  1268
augccaccaa guggauuaag acuacuacca uuacuauuac cacuauuaug gcuacuagua       60

uuaacaccug gaagaccagc ugcaggccua ucaaccugca aaacaauaga cauggaacua      120

guaaaacgaa aaagaauaga agcaauaaga ggccaaauac uaucaaaacu aagauuagca      180

ucaccaccuu cccaaggaga aguaccacca ggcccacuac cagaagcagu acuagcacua      240

uacaacucca caagagacag aguagcaggc gaaucagccg aaccagaacc agaaccagaa      300

gcugacuacu acgcaaaaga aguaacuaga guauuaaugg uagaaacaca caacgaaauc      360

uaugacaaau uuaaacaauc uacacauucu auauauaugu ucuucaauac aagcgaauua      420

cgagaagcag uacccgaacc aguacuauua ucaagagcug aacuccgauu acuaagauua      480

aaacuaaaag uagaacaaca cguagaacua uaccaaaaau auucuaauaa uucauggaga      540

uaucuuagca auagauuacu agcaccaucc gacucaccug aauggcuauc auuugaugua      600

acaggaguag uacgucaaug gcuaucacga ggcggagaaa uagaaggauu uagauuaagc      660

gcucacugca gcugugacuc aagagacaac acauuacaag uagacaucaa cggauucaca      720

acaggaagaa gaggagaucu agccacaaua cacggaauga acagaccauu ucuacuauua      780

auggcaacac cacuagaaag agcacaacau cuacaaucuu caagacacag aagagcauua      840

gacacaaacu acugcuuuuc aagcacagaa aaaaauugcu gcgucagaca auuauauaua      900

gauuucagaa aagauuuagg cuggaaaugg auacaugaac caaaaggaua ccacgcaaac      960

uucugccuag gaccaugccc auacauuugg ucauuagaua cccaauacuc aaaaguucuu     1020

gcauuauaca accaacacaa cccuggagca agugcagcac cauguugcgu accccaagca     1080

uuagaaccac uaccaauagu auauuacguu ggccgaaaac ccaaaguaga acaacuauca     1140

aacaugauag ucagaucaug uaaauguuca uaa                                  1173


<210>  1269
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  1269
augcacuacu gcguacucuc agccuuccua auacuacacc uaguaacagu agcauuaagc       60

uuaucaacau gcucaacacu agacauggau caauucauga gaaaaagaau agaagcaaua      120

agaggccaaa uacuaucaaa acuuaaauua acaucaccac cagaagacua ucccgaacca      180

gaagaaguac caccagaagu aauaucaaua uauaacucaa caagagaccu auuacaagaa      240

aaagcaagcc gaagagcagc agcaugcgaa cgagaaaggu cagacgaaga auacuacgcc      300

aaagaaguau acaaaauaga caugccaccc uucuucccau cagaaaaugc cauacccccc      360

acauuuuaca gaccauacuu cagaaucgua agauucgacg uaucagcaau ggaaaaaaac      420

gcaucaaauc uaguuaaagc agaauucaga guauucagac uacaaaaccc aaaagcaaga      480

guaccagaac aaagaauaga acuauaccaa auacuuaaau ccaaagaucu aacaucaccu      540

acacaaagau auauagacuc aaaaguagua aaaacuagag cagaaggcga auggcuaucc      600

uucgacguaa cagacgccgu ucacgaaugg cuucaccaca aagaccgaaa cuuaggauuc      660

aaaauaucac uucacugucc auguugcaca uuuguccccu caaauaacua cauaaucccc      720

aauaaaucag aagaacucga agcaagauuc gccggaauag acggaacuag cacauauacc      780

uccggagacc aaaaaaccau aaaaucuaca agaaaaaaaa acucuggaaa aacaccacac      840

uuacuauuaa ugcuacuacc cucauaccga cucgaaucuc aacaaacaaa cagacgaaaa      900

aaaagagcau uagacgccgc uuauuguuuc agaaauguac aagauaacug cugccuacga      960

ccacuauaca uagauuucaa aagagaucua ggcuggaaau ggauccauga accaaaaggc     1020

uauaacgcaa acuucugcgc uggagcaugc ccauaccuau ggucaucaga cacacaacau     1080

ucaagaguau uaucacuuua caacaccaua aaucccgaag caucagcaag ccccuguugc     1140

guaucacaag accuagaacc acuaaccauc cuauacuaua uaggaaaaac uccaaaaaua     1200

gaacaacuau cuaauaugau aguaaaauca ugcaaaugcu cuuaa                     1245


<210>  1270
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  1270
augaaaaugc acuuacaaag agcccuagua guccuagcuu uacuuaacuu cgcaaccgua       60

ucccuaagcc uaucaacuug uacaacccua gacuuuggac acauaaaaaa aaaacgcgua      120

gaagcaauua gaggacaaau auuaucuaaa cuaagauuaa ccucaccacc agaaccaaca      180

guaaugacac auguaccaua ccagguauua gcacuauaca auucaacacg cgaacuacua      240

gaggaaaugc auggagaaag agaagaagga ugcacacaag aaaacacaga aucagaauac      300

uacgcaaaag aaauccauaa auucgacaug auacaaggau uagcagaaca caacgaacua      360

gcaguaugcc caaaaggaau aacaucaaaa guauuuagau ucaauguauc uucaguugaa      420

aaaaauagaa cuaaccucuu uagagccgaa uuccgcguau uaagaguccc caacccaagc      480

agcaaacgaa acgaacaaag aauagaacua uuccaaauac uaaggccaga cgaacacaua      540

gcaaaacaaa gauauauagg aggcaaaaau uuacccacaa gagguacagc agaauggcua      600

ucauucgaug uaacagauac cguaagagaa uggcuacuaa gaagagaaag uaaucuaggc      660

cuagaaauau caauacauug uccaugucac acauuccaac caaacggaga cauauuagaa      720

aacauacacg aaguaaugga aauaaaauuc aaaggaguag acaacgaaga ugaucacgga      780

cgaggcgauc uaggcagauu aaaaaaacaa aaagaccacc acaauccaca ccuaauauua      840

augaugauac caccacacag acuagacaau ccaggccagg gaggccaaag aaaaaaaagg      900

gcacuagaca ccaacuacug cuucagaaac cuagaagaaa acugcugcgu aagaccacua      960

uacauugacu ucagacaaga ccuaggcugg aaaugggucc augaaccaaa aggauacuac     1020

gccaacuuuu gcucaggacc augcccauac cucagaucag cagacacaac ccacucaaca     1080

guauuagguu uauacaacac auuaaaccca gaagcaagug ccuccccuug uugcguacca     1140

caagaccuag aaccauuaac cauauuauau uauguaggac gaacaccaaa aguagaacaa     1200

cuaucaaaua ugguaguaaa aucaugcaaa uguagcuaa                            1239


<210>  1271
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  1271
auggcuccug uagccguaug ggcagcucua gccguaggau uagaauuaug ggcugcugcc       60

caugcacuac cugcccaagu ugcuuuuaca ccauacgcac cagaaccugg uucaacaugu      120

agauuaagag aauauuauga ucaaacugcu caaauguguu guucaaaaug uagcccuggu      180

caacaugcca aaguauucug uacuaaaacu ucugauaccg uaugugauuc augugaggau      240

ucaacauaua cacaauuaug gaauugggua ccagaauguu uaucaugugg aucucgaugu      300

ucaucagauc aaguagaaac acaagcuugu acaagagaac aaaauagaau auguacuugu      360

agaccagguu gguacugcgc cuuaucaaaa caagaaggau guagacuaug cgccccacua      420

cgaaaaugua gaccaggauu ugguguugca cguccaggaa cagaaacauc agacguagua      480

uguaaaccau gcgcucccgg uacauucuca aauacaacau cauccaccga uauaugucga      540

ccacaucaaa uauguaaugu aguagcaaua ccaggaaaug caucuaugga cgcaguaugu      600

acaucaacau cacccacaag aucaauggca ccaggugcug uccaucuacc acaaccuguu      660

ucaacaagau cacaacauac acaaccuaca cccgaaccau ccacagcacc aaguaccuca      720

uuucuuuuac cuaugggacc aucaccaccu gcagaaggau caacaggaga uuuugcacuu      780

ccaguaggac uaauaguugg aguaacugca cuaggauuau uaauaauugg agucguaaau      840

uguguaauaa ugacacaagu aaaaaaaaaa ccauuaugcu uacaacgaga agccaaaguc      900

ccucauuuac cagcagacaa agcuagagga acccaaggac cagaacaaca acaccuacuc      960

auaaccgcac cuucaucauc uucaucaucu uuagaaucau cugcaucugc auuagauaga     1020

agagcaccca caagaaauca accacaagca ccuggaguug aagcuuccgg ggcaggugaa     1080

gcucgagcuu caacaggauc uucagauuca ucuccaggug gucauggaac ccaaguuaau     1140

guaacuugca ucguaaaugu auguucauca ucagaucacu caucacaaug uucaucacaa     1200

gcaaguucaa cuaugggaga uacugacuca agcccaucgg aaucaccuaa agaugaacaa     1260

guaccauuua guaaagaaga augugcauuu agaucucaac uugaaacacc agaaacuuua     1320

uuaggaagua cagaagaaaa accacuacca uuaggaguac ccgaugcagg gaugaaaccu     1380

uccuaa                                                                1386


<210>  1272
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  1272
augccaguaa ugaggcuauu uccauguuuu uuacaauuac uagcaggauu agcauuacca       60

gcaguaccac cacaacaaug ggcauuaagu gcaggaaaug gaaguucaga aguagaagua      120

guaccauuuc aagaaguaug gggaagauca uauuguagag cacuugaaag auuaguagau      180

guaguaagug aauauccaag cgaaguagaa cauauguuuu caccaucaug uguaaguuua      240

uuaagaugua caggauguug uggagaugaa aaucuacauu guguaccagu agaaacagca      300

aauguaacaa ugcaauuacu aaaaauaaga aguggagaua gaccaucaua uguagaauua      360

acauucaguc aacauguaag augugaaugu agaccauuaa gagaaaaaau gaaaccagaa      420

agaagaagac caaaaggaag aggaaaaaga agaagagaaa aacaaagacc aacagauugc      480

cauuuaugug gagaugcagu accaagaaga uaa                                   513


<210>  1273
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  1273
augacagaca gacaaacaga uacagcaccu ucaccaagcu aucacuuauu accugguaga       60

agaagaacag uagaugcagc agcuaguagg ggacaaggac cagaaccagc uccaggagga      120

gguguagaag gaguaggggc aagaggagua gcuuuaaaau uauuuguaca acuuuuagga      180

uguagcaggu uuggaggagc gguuguaaga gccggugaag cagaaccguc aggagcagca      240

agaucagcaa gcucaggaag ggaagaacca caaccagaag aaggugaaga agaagaagaa      300

aaggaagaag aaaggggacc acaauggcga cugggagcaa gaaagccagg uaguuggaca      360

ggagaagcag caguaugcgc agacucugca ccagcagcaa gagcaccgca agcauuagcu      420

cgagcaagug gaaggggagg aagaguagcu cgaagaggag cagaagaauc aggaccucca      480

cacaguccaa guaggagagg aagugcaagc agggcaggac cagggagagc aagcgaaaca      540

augaauuuuc uauugaguug gguacauugg agccuagccc uauuauuaua uuuacaucau      600

gcuaaauggu cacaagcagc accaauggca gaaggaggag gacaaaauca ucaugaggua      660

gugaaauuua uggauguaua ucaaagauca uauugucauc caauagaaac auuaguugac      720

auauuucaag aauauccaga ugaaauagaa uauaucuuua aaccuagcug ugucccauug      780

augagaugug gaggauguug uaaugaugag ggauuagaau gcguaccaac agaagaaagu      840

aacauaacaa ugcaaauaau gcgaauaaaa ccacaucaag gacaacauau aggagaaaug      900

ucauuuuugc aacauaacaa augcgaaugc aggccaaaaa aagacagagc aagacaagaa      960

aaaaaaagug uuagaggaaa aggaaaaggu caaaaaagga aaagaaaaaa aaguagauau     1020

aaaaguugga guguauaugu aggagcaaga uguuguuuaa ugccauggag ucuaccggga     1080

ccacauccau guggaccuug cagugagagg agaaaacacu uauuuguuca agacccacaa     1140

acauguaaau guucuuguaa aaacacugau agcagaugua aagcucgaca auuggaauua     1200

aaugaaagga cauguagaug ugauaaacca agaagauaa                            1239


<210>  1274
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  1274
augaacuucc uauuaagcug gguacacugg ucacuagcau uauuauuaua uuuacaucac       60

gccaaauggu cacaagcagc accaauggca gaaggaggag gacaaaacca ccacgaagua      120

guaaaauuua uggauguaua ccaaagaagc uauugccauc caauagaaac acuaguagac      180

auauuccaag aauauccaga ugaaauagaa uauauauuua aaccauccug cguaccauua      240

augagaugcg gaggaugcug caacgacgaa ggacuagaau gcguaccaac agaagaaagu      300

aauauaacaa ugcaaauaau gagaauaaaa ccacaccaag gacaacacau aggcgaaaug      360

aguuucuuac aacauaacaa augcgaaugc agaccaaaaa aagacagagc aagacaagaa      420

aaaaaaagcg uaagaggaaa aggaaaagga caaaaaagaa aaagaaaaaa aagcagauac      480

aaaagcugga gcguauacgu aggagcaaga ugcugcuuaa ugccaugguc acuaccagga      540

ccacacccau gcggaccaug uucagaaaga agaaaacauc uauuuguaca agacccacaa      600

acauguaaau gcucaugcaa aaacaccgac aguagaugua aagcaagaca acuagaacua      660

aaugaaagaa ccuguagaug ugacaaacca agaagauaa                             699


<210>  1275
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  1275
augucaccac uauuaagaag acuacuauua gcagcauuac uacaacuagc accagcacaa       60

gcuccaguaa gccaaccaga cgcacccgga caucaaagaa aaguaguauc auggauagau      120

guauacacaa gagcaacaug ucaaccaaga gaaguuguag ucccacuaac aguagaauua      180

augggaacag uagcaaaaca auuaguacca ucaugcguaa ccguacaaag augcggagga      240

uguugcccag acgauggcuu agaaugcgua ccaacuggac aacaucaagu aagaaugcaa      300

auacuaauga uaagauaccc aucaucacaa uuaggagaaa ugucauuaga agaacauuca      360

caaugcgaau gcagaccaaa aaaaaaagac ucagcaguaa aaccagacag agcagcaaca      420

ccacaucaua gaccacaacc aagaucagua ccaggauggg acucagcacc aggagcacca      480

ucuccagcag acauaacaca uccaacacca gcaccaggac caucagcaca ugcagcaccc      540

ucaacaacaa gugcacuaac accaggacca gcagcagcag cagcugacgc agcagcauca      600

ucagucgcaa aaggaggagc cuaa                                             624


<210>  1276
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  1276
augcaccuau uaggauucuu uagcguagcg ugcaguuuau uggcagcagc acuauuacca       60

gguccacgug aagcaccagc cgcagccgca gcuuucgaau caggauuaga cuuaagcgac      120

gcugaacccg acgcaggcga agcaacagca uacgcuucaa aagaucuaga agaacaacua      180

agaucuguau cuucaguaga cgaauuaaug acaguacuau acccagaaua uuggaaaaug      240

uauaaaugcc aacuaagaaa aggagguugg caacacaaua gagaacaagc aaacuuaaac      300

uccagaacag aagagacuau aaaauuugca gcagcacauu acaacacaga aauucuaaaa      360

ucaauagaca augaauggag aaaaacucaa uguaugccaa gagaaguaug cauagacgua      420

gguaaagaau ucgguguagc caccaacaca uuuuuuaaac caccaugcgu aucaguauau      480

agaugcggag gcuguugcaa uucagaagga uuacaaugua ugaauaccuc uacaagcuac      540

cuaucaaaaa cacuauucga aauaacugua ccauuaucac aaggaccaaa accaguaaca      600

auaucauuug caaaccacac aucaugucga ugcaugucaa aauuagacgu auaccgacaa      660

guacacagua uaauaagaag aucacuaccc gcaacacuac cacaaugcca agcagcaaau      720

aaaacaugcc caacuaacua cauguggaau aaucauauuu guagaugccu agcacaagaa      780

gauuucaugu ucucaaguga ugcaggugac gacucuacug acggauuuca ugacauaugu      840

ggaccaaaua aagaacuaga cgaagaaaca ugucaaugcg uaugcagagc aggacuucga      900

ccagcauccu gugguccaca uaaagaacua gauagaaauu caugccaaug uguuuguaaa      960

aauaaauuau uccccagcca augcggagca aauagagaau uugaugaaaa uacaugccaa     1020

uguguaugua aaagaaccug cccaagaaau caaccacuaa acccaggaaa augcgccugc     1080

gaaugcacag aaaguccaca aaaaugucua uuaaaaggua aaaaauucca ucaccaaaca     1140

uguucaugcu acagaagacc augcacaaac agacaaaaag caugugaacc uggauuuuca     1200

uauucagaag aaguuuguag auguguucca ucauacugga aacgaccaca aaugagcuaa     1260


<210>  1277
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  1277
auguacagag aauggguagu aguaaacgua uucaugaugc uauauguaca acuuguacaa       60

ggaagcucaa augaacacgg accaguaaaa agaucaucac aguccacacu agaaagauca      120

gaacaacaaa uaagagcagc auccucucua gaagaauuac uaagaaucac acauuccgaa      180

gacuggaaau uauggcgaug ucgacuacgc uuaaaaagcu uuacuaguau ggacucacgc      240

ucagcaucac auagaaguac aagauuugca gcaacauucu acgacauaga aacacuaaaa      300

guaauagaug aagaauggca aagaacacaa ugcucaccaa gagaaacaug cgucgaagua      360

gcaucugaac ucggaaaauc caccaauaca uucuucaaac caccaugcgu uaacguauuu      420

agaugcggag gauguugcaa cgaagaauca cuaauaugca ugaauacauc cacaucauac      480

auaucaaaac aacuauucga aauauccgua ccauuaacau caguaccaga acuaguacca      540

guaaaaguag caaaucacac aggaugcaaa ugccuaccaa cagcaccaag acacccuuac      600

agcauaauaa gaagaucaau acaaauaccc gaagaagaca gaugcuccca cagcaaaaaa      660

uuaugcccaa ucgacaugcu augggacuca aacaaaugca aaugcguacu acaagaagaa      720

aacccacuag cagguacaga agaccacuca caccuacaag aaccagcauu augcgguccu      780

cacaugaugu ucgacgaaga uagaugcgaa ugcguaugca aaacaccaug uccaaaagac      840

uuaauacaac acccaaaaaa uugcuccugu uuugaaugua aagaaucacu agaaacaugc      900

ugccaaaaac acaaauuauu ucaucccgau acaugcucau gcgaagacag augcccauuc      960

cacacaagac caugcgcaag uggaaaaaca gccugcgcca agcacugccg auucccaaaa     1020

gaaaaaagag cagcucaagg accacacuca cgaaaaaauc cauaa                     1065


<210>  1278
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__AAA59606.1__signal peptide-HLA-A2-SP

<400>  1278
auggcaguaa uggcaccaag aacauuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg ca                                                           72


<210>  1279
<211>  69
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  1279
auggaugcaa ugaaaagagg auuauguugu guauuauuau uauguggagc aguauuugua       60

aguccaagu                                                               69


<210>  1280
<211>  81
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_000790.2__signal peptide-HsEPO

<400>  1280
auggguguac augaaugucc agcuuggcuu uggcuuuuac uuucacuuuu aucuuuaccu       60

uuagguuuac cuguacuugg a                                                 81


<210>  1281
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_000468.1__signal peptide-HsALB

<400>  1281
augaaauggg uuacuuuuau uucucuucuu uuucuuuuuu cuucugcuua cucu             54


<210>  1282
<211>  18
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from 
       Artificial____cleavage site-Furin

<400>  1282
agaagaagga ggaagaga                                                     18


<210>  1283
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  1283
auggacucag acgaaacagg uuucgaacac uccggauuau ggguaucagu auuagcagga       60

uuacuauuag gagcaugcca agcacaucca auaccagacu caucaccacu ucuacaauuc      120

ggaggacaag uaagacaaag auacuuauac acagaugacg cccaacaaac agaagcacac      180

uuagaaauaa gagaagacgg cacagucgga ggagcagcag accaaucacc agaaucuuua      240

uuacaauuaa aagcauuaaa accaggagua auacaaauau uaggaguaaa aacaucaaga      300

uuucuaugcc aaagaccaga cggagcauua uacggaucau uacauuucga cccagaagca      360

uguucauuca gagaauuauu acuagaagau gguuauaaug uauaucaauc ugaagcacac      420

ggauuaccac uacaucuacc aggaaauaaa ucaccacaua gagacccagc accaagagga      480

ccagcaagau ucuuaccauu acccggauua ccuccagcac uaccugaacc accaggaaua      540

cuagcaccac aaccaccaga uguaggauca uccgacccau uaucaauggu aggaccauca      600

caaggaagaa guccaucaua cgcaucauaa                                       630


<210>  1284
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  1284
augcacucau ucccuccacu auuauuauua cuauuuuggg gaguaguauc acacaguuuc       60

ccugcaaccu uagaaacaca agaacaagac guagaccuag uucaaaaaua cuuggaaaaa      120

uacuacaacc uuaaaaauga cggaagacaa guagaaaaac gaagaaauuc aggaccaguc      180

guagaaaaac uaaaacaaau gcaagaauuu uucggacuaa aaguuacagg aaaaccagau      240

gcagaaacac uaaaaguaau gaaacaaccu agauguggag uacccgacgu agcccaauuu      300

guauuaacag aaggcaaccc aagaugggaa caaacccacu uaaccuacag aauagaaaau      360

uacacaccag aucuaccuag agccgacgua gaucaugcga uagaaaaagc auuucaauua      420

uggaguaaug uaacuccacu aacauuuaca aaagucucag aaggacaagc ggacauaaug      480

auauccuucg uaagaggaga ucacagagac aauaguccau ucgacggacc aggcggaaac      540

cuagcacacg cuuuccaacc aggacccggc auaggaggag augcacacuu cgacgaagac      600

gaaagaugga caaacaacuu cagagaauau aaccuccaca gaguagcugc acaugaacua      660

ggacauucau uaggacuuag ccacagcaca gacauaggag cacuaaugua cccuucauau      720

acauuuucag gagacguaca auuagcacaa gacgauauag acggaauaca agcaauauau      780

ggaagaucac aaaauccugu acaaccgauc ggaccucaga caccaaaagc augcgauagc      840

aaacuuaccu ucgacgcuau aacaacaauu agaggcgaag uaauguucuu caaagaccga      900

uuuuacauga gaacaaaucc auucuauccc gaaguagaau uaaacuuuau auccguauuu      960

uggccacaac ucccuaacgg auuagaagcc gcauacgaau uugcagauag agacgaagua     1020

agauuuuuca aaggaaacaa auacugggcu guacaaggac aaaacguacu acacggauau     1080

ccaaaagaca uauacucauc auucggcuuu ccccgaacag uaaaacauau agaugcagca     1140

uuaucagaag aaaacacagg aaaaacauau uucuuuguag ccaacaaaua cuggagauau     1200

gaugaauaca aaagaucaau ggacccaggu uacccaaaaa ugauagcaca ugauuuucca     1260

ggaauuggac auaaagucga cgccgucuuc augaaagacg gauucuucua uuucuuucau     1320

ggaacuagac aauauaaauu cgacccaaaa acaaaaagaa uauuaacacu acaaaaagca     1380

aacucuuggu ucaacuguag gaaaaauuaa                                      1410


<210>  1285
<211>  1170
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_002412.1__HsMMP1(1-19,100-469)

<400>  1285
augcacucau uuccaccauu acuacucuua uuauuuuggg gaguaguauc acacucauuc       60

guacuaacag aaggaaaucc aagaugggaa caaacacacc uuaccuacag aauagaaaau      120

uacacaccag aucuaccaag agcagacgua gaccacgcaa uagaaaaagc auuucaauua      180

uggucaaacg uaacaccauu aacauucaca aaaguaucag aaggacaagc agacauaaug      240

auaucauucg uaagaggaga ccacagagac aauucaccau uugauggacc aggagguaau      300

cuggcacacg cauuccaacc aggaccagga auaggaggag acgcacacuu cgacgaagac      360

gaaagaugga caaacaacuu cagagaauac aaccuacaca gaguagcagc ccaugaacua      420

ggacacucac uaggacuauc acacucaaca gacauaggag cccuaaugua uccauccuac      480

acauucucag gagacguaca acucgcgcaa gacgacauug acggaaucca agcuauauac      540

ggaagaucac aaaacccagu acaaccaaua ggcccccaaa caccaaaagc augugacuca      600

aaacuaacau uugaugcaau aacaacaaua agaggcgaag uaauguucuu caaagacaga      660

uucuacaugc gcacaaaucc auucuaccca gaagucgaau uaaacuucau aucaguauuc      720

uggccccaau uaccaaacgg auuagaagcc gccuacgaau uugcagaccg agacgaagua      780

agauucuuca aaggaaacaa auauugggca guacaaggac aaaacguauu acacggauau      840

ccaaaagaca uauacuccuc auuuggcuuu ccaagaacag uaaaacauau cgacgcagca      900

cucuccgaag aaaacacagg aaaaacauac uucuuuguag caaacaaaua cuggagauau      960

gacgaauaua aaagaucaau ggacccggga uacccaaaaa ugauagcaca ugacuuccca     1020

ggaauaggac acaaaguaga cgccguauuc augaaagacg gauuuuucua cuucuuucac     1080

ggaacuagac aauacaaauu cgacccaaaa acaaaaagga uacuaacauu acaaaaagca     1140

aacucauggu uuaacugccg caaaaacuaa                                      1170


<210>  1286
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Clostridium 
       histolyticum__BAA77453.1__ColG

<400>  1286
augaagaaaa auauacuuaa aauacucaug gacucauaca guaaagaaag caaaauucaa       60

acgguucgaa gaguaaccag ugucagccua uuagcaguau aucuaacuau gaauacuagc      120

agcuuaguac ucgcgaaacc aauugaaaau acaaaugaca caaguauuaa aaauguagaa      180

aaauugagaa augcaccaaa ugaagaaaac ucgaagaaag uagaagauag caaaaaugau      240

aaaguugagc auguuaaaaa cauagaagaa gcaaaagucg aacagguggc uccagaagua      300

aaaucaaaaa gcacacucag aucagcaagu aucgcaaaca cgaacaguga gaaauaugau      360

uuugaauacc ugaauggccu cucauauaca gaauuaacaa acuuaauuaa aaauauaaaa      420

uggaaucaaa ucaacggcuu auucaauuac aguaccggaa gucagaaauu cuuuggggac      480

aaaaaccgag uacaagcaau aauuaaugca uuacaagaau cagggcgaac auauacagcc      540

aacgauauga aaggaauuga aacauucacc gagguuuuac gagcuggcuu cuauuugggc      600

uacuacaacg auggacuauc cuauuugaac gauagaaacu uucaggauaa auguauacca      660

gcaaugaucg caauacagaa gaacccaaac uucaaauuag gaacagcagu acaagaugaa      720

guaauuacca gucuugguaa auuaauugga aacgcaagcg cgaaugcuga aguuguaaau      780

aacugugucc cagucuuaaa acaauuuaga gagaauuuaa aucaauaugc accagauuac      840

guuaaaggaa cagcgguuaa ugaauuaaua aaaggaauag aguucgacuu uagcggagca      900

gcuuacgaaa aagacguaaa aacuaugccu ugguacggaa agauugaucc auucauaaac      960

gaauuaaaag cauugggccu cuacggaaau auaacaucag cuacagaaug ggccagcgau     1020

guggguauau acuaucuuag uaaauucggu cuuuauagua caaacaggaa ugauaucguu     1080

caaucacuag aaaaagcagu agauauguau aaauacggaa aaauagcauu uguggcaaug     1140

gaaagaauaa caugggacua ugauggaaua ggaucuaacg gcaagaaagu agaccaugac     1200

aaauuucucg acgaugccga aaaacacuac uuaccaaaaa cguauacauu ugacaaugga     1260

acauuuauca uaagagcggg ugacaaagua agugaagaga aaauaaaaag acuauacugg     1320

gcaucuagag aaguaaaauc ucaauuucac agggucgucg ggaaugacaa agcacuagaa     1380

guaggaaacg ccgacgaugu ccucacaaug aaaauauuca acagccccga agaauauaaa     1440

uucaauacua auauaaaugg aguuagcaca gacaauggcg gauuauauau agaaccacga     1500

gggacuuucu acacguauga aagaacacca caacaaucaa uauucagcuu agaagaacug     1560

uuuagacaug aauauacuca uuacuuacaa gcucgauauu uaguggaugg auuaugggga     1620

caaggccccu ucuacgagaa aaacagacua acuugguucg acgaaggaac agcagaguuc     1680

uucgccggcu caaccaggac aucaggagug cuuccgagaa aaucaauacu aggcuaucuu     1740

gcaaaagaua aaguagacca cagauacagc cucaagaaaa cauuaaauuc aggauaugau     1800

gauagcgauu ggauguuuua uaauuauggg uuugcuguag cccacuauuu auaugaaaaa     1860

gauaugccaa cauuuauaaa aaugaauaaa gcaauucuaa auaccgacgu uaaaagcuau     1920

gaugaaauaa uaaagaaauu aucagacgac gcgaacaaaa acacagaaua ucaaaaucac     1980

auacaagaau uagccgacaa auaucaagga gcaggcauac ccuuaguguc agacgacuau     2040

uuaaaagauc auggauauaa gaaagcgucc gaaguauauu cugaaauauc uaaagcggca     2100

agccuaacaa auacauccgu aacagcggaa aaaucacaau acuuuaauac auuuacacua     2160

agaggaacau auacaggaga aacaaguaaa ggcgaauuua aagacuggga cgaaaugagc     2220

aagaaacugg acggaacacu agaaagccua gcuaaaaacu cauggagcgg auauaaaaca     2280

uuaacggcau auuuuaccaa uuaccgagua acguccgaca acaaaguaca auaugacguu     2340

guauuucacg gcguuuuaac agauaacgca gauauaagua auaacaaagc accaauagca     2400

aaaguuacag gcccaucgac aggugccgua gguagaaaca uugaauuuuc uggaaaagau     2460

ucaaaagaug aagauggaaa aaucguauca uacgacuggg acuuuggaga cggagcaaca     2520

ucaagaggga aaaauucagu ccaugcauac aagaaagcug gaacauauaa cguaacauua     2580

aaaguuaccg augauaaagg ugcgacagca acugaaucuu uuacaaucga aaucaaaaac     2640

gaagauacaa caacaccaau aacgaaagaa auggaaccca augacgauau aaaagaagcu     2700

aauggaccaa uagucgaagg aguaaccguc aaaggugacc uaaacggcuc cgacgacgcu     2760

gauacauucu auuuugaugu uaaagaagau ggagauguga caauagaacu accauauuca     2820

ggaucuagua acuuuaccug gcugguauau aaagaaggcg augaucaaaa ucauaucgcu     2880

agugguauag acaaaaauaa cagcaaaguu ggaacauuua aaagcacaaa agguagacau     2940

uacguauuca uuuacaaaca cgauucagca ucaaauaucu cauacucuuu aaauauaaaa     3000

ggcuuaggua augaaaaacu gaaagagaaa gaaaauaaug auucgucaga caaagcuaca     3060

gugauaccaa auuucaauac aacuaugcaa ggaucacugc uaggagauga cagccgugau     3120

uauuacagcu ucgaaguaaa agaagaagga gagguaaaca ucgaauuaga uaagaaagau     3180

gaauuuggag uaacauggac auuacaucca gaauccaaca uaaacgacag aauaacauac     3240

ggacaaguug augguaacaa aguaaguaau aaaguaaaau ugaggccugg aaaauacuac     3300

cuguuaguau auaaauacag ugggucagga aacuacgaac uacgaguuaa caaauaa        3357


<210>  1287
<211>  3081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118)

<400>  1287
augaaauggg uaacuuuuau aagucuucua uuucuauuuu caucggcaua uaguauagca       60

aacacaaacu cagaaaaaua ugacuuugaa uaucuaaaug gauuaucaua uacagaauua      120

acaaaccuga ucaaaaacau aaaauggaau caaauaaacg gauuauuuaa cuauagcacg      180

ggaucacaga aauuuuucgg cgauaaaaau agaguacaag caauuauaaa ugcucuccaa      240

gaaucuggca gaacguauac agcaaacgau augaaaggaa ucgaaacuuu uacagaaguc      300

cugagagcag guuuuuacuu agguuauuac aacgacgggc uaagcuaucu aaaugauaga      360

aacuuccaag acaaauguau accagcaaug auugcaauac agaaaaaccc caauuuuaaa      420

uuaggaacag caguucaaga cgaaguuaua acaucucuug gcaaacuuau agggaacgca      480

agcgcaaacg cagaaguagu aaacaacugu guaccgguau uaaaacaauu cagagaaaau      540

uuaaaucaau acgcaccaga cuauguaaaa ggaacagcag uaaacgaacu aauaaaagga      600

auagaauuug auuucagcgg agccgcauau gaaaaggaug ucaaaacuau gccgugguac      660

ggaaaaauag acccauuuau aaaugaacuu aaagcacuag guuuauacgg aaacaucaca      720

agcgcaacug aaugggcauc agauguugga auuuauuacc uaucuaaauu uggacuauac      780

ucaaccaaca ggaacgauau agugcaaucu cuggaaaaag cuguagacau guauaaauau      840

ggaaaaauag cuuucgucgc aauggaaaga auaacuuggg auuaugaugg uauuggauca      900

aacggcaaaa agguagauca cgauaaauuc uuagaugacg cagaaaagca cuacuuacca      960

aaaacguaua cauucgacaa cgggacuuuu auaaucagag caggcgauaa aguauccgaa     1020

gagaaaauaa aaagauuaua cugggcuuca agggaaguaa aaucucaauu ccaccgagua     1080

guaggaaaug auaaagcauu agaagugggu aacgcugaug auguauuaac aaugaaaaua     1140

uucaacagcc cugaagaaua caaguucaau acaaauauaa acggagucuc uaccgauaac     1200

ggaggcuuau acauugaacc aagaggaaca uuuuacacau augaaagaac uccacaacaa     1260

agcauauuca gccuugagga acuauuccga cacgaauaua cacauuacuu acaagccagg     1320

uaucuuguag auggacuuug gggacaggga ccuuucuaug aaaagaauag acuaaccugg     1380

uucgacgaag gaacagcaga guucuuugca gguucaacaa gaacaucugg aguauuacca     1440

cgaaaaucaa uucucgguua uuuagcaaaa gauaaaguag aucauagaua uucacuaaag     1500

aaaaccuuga acucaggaua cgacgacagu gacuggaugu ucuacaauua cggauuugca     1560

guagcacacu auuuauauga aaaagauaug ccuacauuca uuaaaaugaa caaagcaaua     1620

cuaaauaccg augugaaaag cuaugacgaa auaauaaaga aacuuucaga cgaugcgaac     1680

aaaaauacag aauaccaaaa ccauauucaa gaacucgccg acaaauacca aggugcaggc     1740

auuccucuag uaagugacga cuauuuaaaa gaccauggau acaagaaagc aucagaaguc     1800

uauucagaaa ucagcaaagc cgcauccuua acuaauacaa gcgucacagc agagaaauca     1860

caauacuuua auacauucac gcuucgagga acuuauacag gugaaacguc aaaaggagag     1920

uuuaaagauu gggaugaaau gucaaagaaa uuagauggaa cacuagaauc guuagcuaaa     1980

aacucauggu cuggauauaa aacacuaacc gcauacuuua cuaacuacag aguuaccagu     2040

gauaacaaag uacaauacga uguaguauuu cauggaguac uaacagacaa ugcagacauu     2100

agcaauaaca aagcaccaau agcaaaaguu accggccccu caacaggggc aguagguaga     2160

aauauugagu ucucuggaaa agauagcaaa gaugaagaug gaaaaauagu uucauaugau     2220

ugggacuuug gugauggagc aacuagcagg ggcaaaaacu caguucacgc auacaagaaa     2280

gcaggaacau auaacguaac cuuaaaagua accgaugaua aaggagcaac cgccaccgaa     2340

aguuuuacua uagaaaucaa aaacgaagac acaacgacac caauaacaaa agaaauggaa     2400

ccaaaugacg acauaaaaga agcaaacgga ccaauaguag aaggaguaac aguaaaagga     2460

gaccuaaaug gcucggacga ugcagauaca uuuuacuuug augucaaaga ggauggugac     2520

guaaccauag aacuacccua uagcggauca aguaauuuca cuuggcuagu uuacaaagaa     2580

ggagaugacc aaaaccauau ugcaucagga auugauaaaa acaacucaaa aguaggcaca     2640

uucaaaucaa caaaaggacg acauuacguu uucauauaua aacacgacag cgcuucaaac     2700

auaucauauu cucucaacau aaaagguuua ggcaaugaaa aauuaaaaga aaaagaaaau     2760

aacgacucau cagauaaagc aaccguaauc ccaaauuuca auacaacgau gcaaggaucg     2820

cuccucggag augacagucg ugauuacuac ucauuugaag uaaaagaaga aggagaaguu     2880

aauauagaac uagauaagaa agacgaguuc ggaguaacau ggacauuaca cccagagagu     2940

aauaucaacg auagaauuac auauggccaa guugacggaa auaaaguuag uaauaaagua     3000

aaacuuaggc caggaaaaua uuaccugcuc gucuacaaau acucagguag cgguaacuau     3060

gaacuaagag uaaacaaaua a                                               3081


<210>  1288
<211>  3429
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118)

<400>  1288
augaaauggg uaacauucau uagccucuua uuucuauuuu caucagcaua caguaugaag       60

aaaaauauac uaaaaauauu gauggacucc uauaguaaag agagcaaaau acaaacagua      120

aggcgaguaa ccagcgugag uuuacuugcu guauaucuaa caaugaacac aaguagccua      180

guuuuagcaa aaccaauaga aaauacgaau gauaccucca ucaaaaacgu agaaaaacua      240

agaaaugcac caaacgaaga aaauucaaag aaaguagaag auaguaaaaa cgacaaagua      300

gaacauguga aaaacauaga agaagccaaa guagaacaag uagcaccaga agucaaaucu      360

aaauccacuu uaagaagugc gucaaggaga agaagaaaaa gaauagcaaa cacaaauagu      420

gaaaaauacg auuucgaaua ccuaaacgga cuauccuaua cugaacuaac aaaucuaauu      480

aaaaacauaa aauggaauca aauaaacggu uuauuuaacu auuccacagg cucacaaaaa      540

uuuuucggag auaaaaaucg cguucaagca auaauaaaug cccuacaaga aagcgggaga      600

accuacaccg caaaugauau gaaaggaaua gaaacauuca cagaaguacu uagagccggu      660

uucuaucuag guuacuauaa cgacggauua aguuaucuaa augauaggaa cuuccaagau      720

aaaugcauac cagcaaugau cgcaauacag aaaaauccaa auuucaaauu gggaacagca      780

guccaagacg aagugauaac aucacuagga aaacuaauag gcaacgcaag ugcaaacgcc      840

gaaguaguaa acaacugugu uccaguacua aaacaauuca gagaaaaccu aaaccaauac      900

gcaccugauu auguuaaagg uacagccguc aacgaacuca uaaaagguau agaguucgac      960

uucucaggag cagcguacga aaaagaugua aaaacaaugc caugguaugg aaaaauugau     1020

ccauuuauua augaauuaaa ggcauuagga uuguacggaa acauaaccuc ggcuacagaa     1080

ugggcaucag auguaggaau auacuaccuu ucaaaauuug gucuauauag cacaaaccgg     1140

aacgauauag uacaaucauu agaaaaagcc guagacaugu auaaauaugg aaaaauagca     1200

uuugucgcaa uggaaagaau aaccugggac uacgacggaa uagggucuaa cgggaagaaa     1260

guagaccaug auaaauuucu cgaugaugcc gaaaaacauu aucuaccuaa aacuuacacu     1320

uucgacaaug gcacauucau aaucagagcu ggcgacaaag uauccgaaga gaaaauaaaa     1380

agauuauauu gggcaucuag agagguaaaa agucaguuuc acagagucgu aggaaaugau     1440

aaagcucuug agguaggaaa cgcagaugac guguuaacaa ugaaaauauu uaauucaccg     1500

gaagaauaca aguucaauac aaacauuaau ggcguaucca cagacaaugg aggacuauau     1560

aucgaaccac gaggaacauu cuauacauau gaaagaaccc cacaacagag uauuuucagu     1620

cuagaagaau uauuuaggca cgaauacacc cauuauuuac aagcacguua ucuaguagac     1680

ggacuauggg gucagggacc cuucuacgaa aagaaccgcu uaacaugguu cgaugaaggu     1740

acugcggaau uuuucgcugg aucaacacga accaguggag uacucccaag aaaaucaauu     1800

uuagguuacc uugcaaaaga uaaagucgau cacagauacu cacucaaaaa gacacuaaau     1860

ucaggauaug augacucaga cuggauguuu uauaauuaug gauucgcagu cgcacacuac     1920

cucuacgaaa aagauaugcc aacguucauu aagaugaaua aggcaauacu aaauacagau     1980

guaaaaucau acgacgaaau cauaaagaaa cuauccgacg acgcaaauaa aaauacagaa     2040

uaccaaaacc auauacaaga acuagcagac aaauaucagg gagcaggcau cccacuugua     2100

agcgacgacu acuugaaaga ccacggauac aagaaagcau ccgaagucua cucagaaaua     2160

uccaaagcag ccucauuaac aaauacgucc guaacugcug agaaaaguca auauuucaac     2220

acauucacac uacguggaac auacaccggc gaaacgagua aaggagaguu caaagauugg     2280

gacgaaaugu caaagaaauu agacgguaca cuagaaucau uagccaaaaa uucauggagc     2340

ggauacaaaa cucuuacggc auacuuuaca aacuauaggg uuacaaguga uaacaaagua     2400

caauaugacg uaguauuuca uggaguccuc acagacaaug cugauaucag caacaacaaa     2460

gcuccuaucg cuaaaguaac ugggcccagu acgggagcag uaggcagaaa cauugaguuc     2520

ucaggaaaag acucaaaaga cgaagauggc aaaauaguau ccuaugauug ggacuuugga     2580

gauggagcaa caucaagagg caaaaacuca guccacgcau acaagaaagc aggaacauau     2640

aauguaacac uuaaaguaac agacgauaaa ggcgcaacag caacagaauc auucacaaua     2700

gaaauuaaaa acgaagauac aacaacacca auaacaaaag aaauggaacc aaacgaugau     2760

auaaaagagg caaacggucc aauaguggaa ggaguaacag uaaaaggcga cuugaauggg     2820

agcgacgacg ccgacacauu uuauuucgac guuaaagagg acggcgacgu aacaauagaa     2880

uuaccauaca guggaucaag caacuuuacg uggcuaguuu auaaagaagg agacgaccaa     2940

aaccauauag caagugguau agacaaaaac aauaguaaag uagguacauu uaaaaguacc     3000

aaaggcagac auuacguauu uauauacaaa cacgauucag caucaaacau aucauauucu     3060

cuaaauauaa aaggauuagg gaaugaaaaa cuuaaagaaa aagagaauaa ugacagcagc     3120

gacaaagcaa cugucauacc caacuuuaac acaacaaugc aagguucacu auuaggagac     3180

gacagucgag auuauuauag cuucgaagua aaagaggaag gagaagucaa uauagaauua     3240

gauaagaaag acgaauuugg aguaacaugg acacuucauc cugaaaguaa uauaaacgau     3300

agaauaacau acggacaagu agacggaaac aaagucucaa auaaaguaaa acuuagacca     3360

gggaaauauu aucuacuugu auauaaauac aguggaucag guaacuauga acuaagaguc     3420

aauaaauaa                                                             3429


<210>  1289
<211>  3105
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  1289
augaacuucu ugaaaauaau ccucaacaga ggaaaaacca ugaaacgaaa augucuguca       60

aaaagauuaa ugcuagcuau aacaauggcc accauauuca cagucaacuc aacacuacca      120

aucuaugcag caguagauaa aaauaaugcu acagcugcag uacaaaacga aucaaaacgu      180

uauacaguuu cguacuuaaa aacauuaaau uauuaugacc ucgucgaucu auugguaaaa      240

acagaaaucg aaaauuuacc agauuuauuc caauacagcu cagaugcuaa agaguucuau      300

gguaacaaaa caagaaugag cuucauuaug gacgaaauag guagaagggc uccacaauau      360

acagaaauag accauaaagg aauaccaacc cuaguagaag uagucagagc cggauuuuau      420

cuuggauucc acaacaaaga auuaaaugaa aucaacaaaa gaucauucaa agaacgagua      480

aucccaagca uauuagcaau acaaaagaau ccaaauuuca aauuaggaac agaaguucag      540

gacaaaauag uuagcgcaac aggacuucua gccggaaaug aaacagcacc uccugaagua      600

guaaauaacu uuacaccaau auugcaggau ugcauaaaga acauagauag auacgcguua      660

gaugaccuaa aaucuaaagc cuuauucaau gugcuugcag ccccaacaua cgacaucacu      720

gaauaucucc gagccacaaa agaaaaacca gaaaacacac caugguacgg gaaaauagac      780

ggauucauaa acgaacucaa gaaacuagca uuauauggua aaauaaacga caacaacuca      840

uggaucauag acaaugguau auaccauaua gccccauuag gaaaacuuca cagcaauaau      900

aaaauaggaa uagagacauu aacagaagua augaaaguau acccuuauuu aaguaugcaa      960

cauuuacaau cagcagacca aaucaaaaga cauuacgaca guaaagacgc ggaaggaaac     1020

aaaauuccau uagacaaauu uaaaaaggaa ggaaaagaaa aauauugucc aaaaaccuac     1080

acauuugacg auggaaaagu cauuauaaaa gccggagcac guguagagga agaaaaagug     1140

aaaagacuuu acugggcauc caaagaagua aauucacaau ucuuucgagu uuacggaauu     1200

gacaaacccc uggaagaagg aaacccagac gacauuuuaa cgaugguaau auacaacagu     1260

ccugaagaau acaaacuaaa caguguacua uauggcuacg auacgaacaa cggaggaaug     1320

uacaucgaac cagaaggaac auucuuuacg uacgaaagag aagcacagga aucaacuuau     1380

acacuagagg aacuauuucg acacgaauac acacacuauc uccaagguag auaugcaguu     1440

ccgggacaau ggggaagaac uaaguuauac gauaaugaca gacuaacaug guaugaagaa     1500

ggaggggccg aguuauucgc gggcaguacc agaacaagug ggauauuacc cagaaaaagc     1560

auuguaucca acauacacaa caccacgagg aauaaccgau auaaacuuuc agauacaguc     1620

cauucaaaau auggagcauc guuugaguuc uacaauuaug caugcauguu uauggauuau     1680

auguauaaua aagacauggg aauacucaac aaauuaaaug accuagcaaa gaacaaugac     1740

guggacggau acgacaacua cauaagagac cuaucaagca acuacgcacu aaaugacaaa     1800

uaucaagacc acaugcaaga aagaauagau aacuaugaaa aucucacagu accuuucguu     1860

gcagaugacu accuaguccg ucaugcauac aaaaauccga acgaaauaua uucagaaauu     1920

ucagaaguug cuaaacuuaa agaugccaaa ucagaaguaa agaaaaguca auacuucagu     1980

acuuuuacac uacgcggaag cuacacugga ggagcuucaa aaggaaaauu agaagaccaa     2040

aaagccauga acaaauucau agacgauagc cucaagaaau uagauacgua uaguuggucu     2100

ggauauaaaa cacuaacagc guauuuuaca aauuauaaag ucgauaguag caacagagua     2160

acauacgaug uaguauuuca uggauauuua ccaaaugaag gagauuccaa aaauucacuc     2220

ccguauggaa aaauaaacgg uacauauaaa gggacagaaa aagagaaaau aaaauucagc     2280

ucagaaggaa guuuugaccc ggacgguaaa auaguaaguu acgaauggga cuucggugac     2340

ggcaauaaau caaacgaaga aaauccagaa cacucuuaug auaaaguagg aaccuacaca     2400

gugaaauuaa aaguaacaga ugauaaaggu gaaucauccg ucaguacgac aacagcagaa     2460

auaaaagauc ugucagaaaa caagcucccg guuauauaua ugcauguacc aaaaagcggc     2520

gcccuaaauc aaaaaguagu cuuuuacgga aaaggaacgu augacccaga cggaaguaua     2580

gcaggauacc aaugggauuu uggggauggu agugacuuua gcagcgaaca aaacccauca     2640

caugucuaca cuaagaaagg cgaguacaca guuacacuca gaguaaugga cucaagugga     2700

caaaugucag agaaaacaau gaaaauaaaa auaacagauc caguauaucc aauuggaacu     2760

gaaaaagaac caaacaauuc uaaagaaaca gccucagguc ccauuguccc uggcauaccu     2820

guaaguggaa caauagaaaa caccagugac caagacuauu ucuauuuuga cguuauaaca     2880

cccggcgaag uaaaaauaga caucaacaaa cuuggauacg gaggagcuac auggguugua     2940

uaugaugaaa acaauaaugc aguaaguuau gcaacugaug auggacaaaa ccuaagcgga     3000

aaauuuaaag cagauaaacc cggacgauau uauauacacu uauauauguu caacggaagu     3060

uauaugccau aucgaauaaa uauagaagga agcguaggaa gauaa                     3105


<210>  1290
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  1290
augaaaagaa aauguuuaag caaaagauua augcuagcca uuacaauggc aacaauuuuc       60

acaguaaaua guacauuacc aauuuacgca gcugucgaca aaaacaacgc aacugcagca      120

guacagaacg aaucaaaacg guauacagug agcuaccuca aaacacuaaa uuauuaugac      180

cuaguagauc uacuuguaaa aacagaaauu gaaaaucuac cagaccuauu ccaauacucc      240

ucagaugcaa aggaauuuua uggaaacaaa acgcgcauga guuucauuau ggacgaaaua      300

ggaaggaggg ccccacagua cacagaaaua gaucauaaag gcauaccaac gcuaguagaa      360

gucguaagag caggauuuua ccuagguuuu cacaacaaag aacucaacga aauaaacaag      420

cgcaguuuua aagaaagagu cauuccauca auauuagcga uccagaaaaa cccuaacuuc      480

aaacuaggaa cagaaguaca agacaaaauu guaucagcga caggacuacu agcaggaaau      540

gagacagcac caccagaagu aguaaauaau uucacaccaa uauuacaaga cugcaucaaa      600

aauauagacc gauacgcauu ggaugacuug aaaagcaaag cauuauuuaa uguacuugcg      660

gcaccaacau augacauaac agaauaccua agagcuacaa aggaaaaacc agaaaacaca      720

ccaugguaug gaaaaauaga cggauuuaua aaugaacuga aaaaguuagc acuauacggu      780

aaaaucaaug acaacaacag cuggauaaua gacaauggga ucuaccauau agccccauua      840

gguaaacuac auucaaacaa caaaauagga aucgaaaccc uaacagaagu aaugaaagua      900

uauccauacc uaagcaugca acacuugcaa agcgcagacc aaauaaaaag gcacuaugac      960

agcaaagaug cagaaggaaa caaaauacca cucgacaagu ucaagaaaga agguaaagaa     1020

aaauauuguc ccaaaacgua uacguucgau gacggaaaag uaaucauaaa agcaggagcc     1080

agaguagaag aagaaaaagu aaaaagacuu uauugggcuu cgaaagaagu caacagccaa     1140

uucuucagag uauaugguau cgacaaaccu cuagaagaag gaaauccaga ugacauucua     1200

acaaugguaa uauacaacuc accggaggaa uacaaauuaa acaguguccu guacggauac     1260

gauacaaaca acgguggcau guauauagaa ccagaaggua cauucuucac uuaugaaaga     1320

gaagcucaag aaagcaccua cacauuagag gaauuauuua gacaugaaua uacucacuau     1380

uuacaaggcc gauaugcagu accaggccaa ugggggcgua caaaauuaua cgauaacgau     1440

agauuaacau gguaugaaga agguggagcc gaacuauucg cagguuccac caggacuuca     1500

ggaauacuac caaggaaauc aauuguaagu aauauacaca auaccacacg uaacaacaga     1560

uacaaauuau ccgacacagu acacucaaaa uacggagcau cauucgaguu cuacaauuac     1620

gcauguaugu uuauggauua uauguauaau aaagauaugg gaauccuaaa caaacuaaau     1680

gacuuagcua aaaauaauga cguugacgga uacgacaauu acauaaggga cuuaaguagc     1740

aacuacgcau uaaacgacaa auaccaagac cauaugcaag aaagaauaga uaacuaugaa     1800

aaucuaacgg uaccauuugu ugcagacgau uauuuaguca gacaugcaua caaaaacccu     1860

aaugaaauau acagugaaau aucagaagug gcaaaacuaa aagacgcuaa aucugaagua     1920

aagaaaagcc aauacuuuag uacauucaca cuucgaggcu cauacacagg aggagcaagc     1980

aaggguaaac ucgaagacca aaaagcaaug aacaaauuua uagaugauuc acuaaagaaa     2040

uuagacacau auaguuggag cggcuauaaa acacuaaccg cauacuuuac uaacuauaaa     2100

guagacucau caaaccgcgu aacauacgac guaguauuuc acggauaccu ccccaaugaa     2160

ggugacagca aaaacucacu acccuauggg aaaauaaaug ggacauacaa agguaccgaa     2220

aaggagaaaa uaaaauuuuc uucugaaggc agcuucgacc cagacggaaa aauagucucc     2280

uacgaauggg acuucgguga uggaaacaaa agcaaugaag aaaauccaga acacaguuac     2340

gacaaaguag ggacuuacac uguaaaacug aaaguuacag augacaaggg cgaaagcucu     2400

guaaguacaa ccacugccga aauaaaagac cuaucagaaa acaaacuucc aguaauauau     2460

augcacguuc cuaaaucugg agcuuugaac caaaaaguag uuuucuacgg aaaaggcacg     2520

uaugacccgg auggaucaau cgcaggcuau caaugggacu uuggcgaugg aagugacuuu     2580

uccagcgaac aaaacccuag ccacgucuau acuaagaaag gagaauauac cgugacauua     2640

cgaguaaugg auucaucagg acaaauguca gagaaaacca ugaaaauaaa aaucacugac     2700

ccaguauauc caauaggaac agaaaaagaa ccaaacaaca guaaagaaac agccucaggu     2760

ccaauaguac cuggaauacc agucucaggc acaauagaaa acacaucaga ccaagacuac     2820

uucuauuuug auguuauaac accaggugaa gucaaaauag auauaaauaa auuaggauau     2880

gguggugcaa caugggucgu auacgaugaa aacaauaacg ccguuaguua cgcaacagac     2940

gauggucaaa accuaucugg gaaauucaaa gcagauaaac cuggaagaua cuauauacau     3000

cuauauaugu uuaacggcag cuacaugcca uauagaauaa auauagaagg gucaguagga     3060

agauaa                                                                3066


<210>  1291
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021)

<400>  1291
augaaauggg uaacuuuuau aucauuauua uuccuauuca guucagcaua uaguguacaa       60

aaugaaucaa aaagguacac aguauccuau cuaaaaacgu uaaauuauua cgauuuagua      120

gaucuccuag ucaaaacuga aauagaaaac uuaccagacc uauuccaaua uucguccgau      180

gcaaaagaau uuuauggaaa uaaaacccga augucauuca ucauggacga aauuggacga      240

agggcaccgc aauacacaga aauagaucac aaagguauuc caacccucgu agaagucgua      300

agagcuggcu ucuaccuagg auuucauaau aaagaauuaa augaaauaaa caaaagguca      360

uucaaagaaa gaguaauacc cuccauauua gcaauacaaa aaaauccuaa cuuuaaacuu      420

ggaacagaag uucaagacaa aaucguuuca gcgaccgguu uacuggcagg caacgaaaca      480

gcaccucccg aagucguaaa caacuucaca ccaauuuuac aagauuguau aaaaaauauu      540

gaucgauacg cuuuagacga ccuuaaaagc aaagcgcuau ucaacguacu cgcagcaccu      600

acauacgaua ucaccgaaua ccuucgagcu acaaaagaaa aaccagaaaa uacuccuugg      660

uauggcaaaa uagacggauu cauaaacgaa uuaaaaaaau uagcuuuaua uggaaaaauu      720

aaugauaaua acucauggau aauagacaau ggaauauauc acauugcacc auuaggaaaa      780

uuacauucua auaauaaaau aggaauagaa acauugacag aaguaaugaa aguguacccc      840

uaccuaagca ugcaacauuu acagucagcu gaucaaauua aacgacacua cgauucaaaa      900

gacgcagaag gcaauaaaau cccacuugac aaauucaaaa aagaaggaaa agaaaaauac      960

uguccaaaaa cauauacauu ugacgacgga aaaguaauaa uaaaagcugg ugcaagagua     1020

gaagaagaaa aagucaaaag acuauauugg gcaagcaaag aaguaaauuc acaauucuuu     1080

cgaguauaug gaauugacaa accccuagaa gagggaaacc cagacgauau acuaacaaug     1140

gugauauaca acucaccaga agaauauaaa cuaaacagug uacuauacgg auacgauaca     1200

aacaauggcg ggauguacau agaaccagaa gguacauucu ucacguauga aagggaagca     1260

caagaaucca ccuacacacu cgaagaacua uucagacaug aauacacuca uuaucuacaa     1320

ggcagauaug ccguaccggg acaaugggga agaacaaaau uauaugacaa cgacagauua     1380

acaugguaug aagaaggagg agcagaacua uuugcuggca guaccagaac aagugggauc     1440

cuucccagaa aaucaauugu gaguaacaua cacaacacaa cgagaaauaa uagauauaaa     1500

cuaagcgaua ccguacauag uaaauaugga gccucguucg aauuuuauaa uuaugccugu     1560

auguucaugg auuacaugua uaacaaagau auggguauau uaaauaaauu aaacgaccuc     1620

gcuaaaaaua augauguaga cggauacgac aacuacauaa gagauuuauc cagcaacuau     1680

gcauuaaaug acaaauauca agaccacaug caagaaagaa ucgacaacua ugaaaaucuu     1740

acuguaccau ucguagcaga cgauuaccua guuagacacg ccuauaaaaa ucccaacgaa     1800

auauauagcg aaauaucuga aguagcaaag cuaaaagacg caaaaagcga agugaaaaaa     1860

ucacaauacu uuucaacuuu cacauugaga ggcucauaca caggaggugc aagcaaagga     1920

aaauuagaag aucaaaaagc aaugaauaaa uuuauagacg acagucuaaa aaaauuagau     1980

acauacucau ggucagguua caaaacacua acggcauacu ucacaaacua uaaaguagau     2040

uccucaaaua gaguaacaua cgaugucguu uuucauggau aucuaccuaa cgaaggagac     2100

agcaagaaua gucuaccaua uggaaaaaua aauggaacgu acaaaggaac ugaaaaagaa     2160

aaaaucaaau ucucaucaga aggcaguuuc gaucccgacg ggaaaauagu aucauacgaa     2220

ugggauuuug gagauggcaa caaaucaaac gaagaaaacc cagaacauuc auaugauaaa     2280

gucggaaccu acacaguaaa acuaaaagua accgaugaca agggagaauc aucgguuucc     2340

accacgacag cugaaauaaa agacuuauca gaaaacaaau uacccguaau auacaugcac     2400

guaccaaaau caggcgcgcu uaaccaaaaa gugguuuucu auggaaaagg cacauacgau     2460

ccagauggaa gcaucgcagg auaccagugg gauuucggag augguucaga uuuuaguucu     2520

gaacaaaauc cuagccaugu auacaccaaa aaaggugaau acacaguuac acuuaggguu     2580

auggacuccu caggacaaau gagcgaaaaa acaaugaaaa uaaaaauaac cgacccagua     2640

uacccaauag gaaccgaaaa ggaaccaaac aauucuaaag aaacagcauc agguccaaua     2700

guaccaggaa ucccaguguc agggacaaua gaaaacacau cagaccaaga cuauuucuau     2760

uucgacguaa uaacacccgg agaaguaaaa auagacauaa acaaauuagg auacgguggc     2820

gccacuuggg uuguauauga cgaaaacaac aacgcaguau cuuaugcaac ugacgacggc     2880

caaaacuuaa guggaaaguu uaaagccgau aaaccuggac gauacuacau acaccuauac     2940

auguucaacg gcaguuacau gccauacaga auaaacauag aagguagcgu uggucgauaa     3000


<210>  1292
<211>  3138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1)

<400>  1292
augaaauggg uaacauucau cagcuuacua uuuuuauuuu caucugccua uuccaugaaa       60

agaaaauguc uaucaaaaag auuaauguua gcaauaacaa uggcuacaau auucacgguc      120

aacaguacac ucccaauaua cgcugcaguc gacaaaaaca acgcgacugc agcacgcagg      180

cgcagaaaaa gaguacagaa ugaaucaaaa cgauacaccg ugucguaccu aaaaacccua      240

aauuacuacg accucguuga ccuauuagua aaaacagaaa uagaaaauuu accagaccuu      300

uuucaauacu caagcgaugc caaggaauuu uacggaaaua aaacaaggau gaguuucaua      360

auggaugaga ucggccgccg agcaccacaa uauaccgaaa uagaucauaa aggaaucccg      420

acguugguug aaguuguuag agcaggauuc uauuuggguu uucacaacaa agaacuaaau      480

gaaauaaaua aacgcagcuu caaagaaaga guaauaccaa gcaucuuagc gauucagaaa      540

aauccuaauu ucaaacuagg aacggaagua caagacaaaa ucgucucagc aacgggauug      600

uuagcgggaa acgaaaccgc uccaccagaa gucguaaaca acuuuacccc cauacuacaa      660

gacugcauca aaaauauaga uagauacgca uuagaugauu uaaaaucuaa agcauuauuc      720

aacguauugg cggcaccaac auaugauaua acagaauauu uaagagcgac aaaagaaaaa      780

ccagaaaaca cuccauggua uggcaaaauu gacggauuua uaaaugaauu aaagaaauug      840

gcccuauacg gaaaaauaaa ugacaauaac agcuggauca uugacaacgg aauauaccac      900

auagcucccu uaggaaaacu acauaguaac aauaaaaucg guauagaaac auuaacugaa      960

guaaugaaag uuuacccaua ucuaaguaug caacauuuac aaucagcaga ucaaauaaaa     1020

aggcacuaug auagcaaaga cgcagaggga aacaaaauac cacuagacaa auuuaagaaa     1080

gagggaaaag aaaaauacug uccaaaaacc uacacauucg augacggaaa aguaaucaua     1140

aaagcaggag caagaguaga agaggaaaaa guaaaacgau uauauugggc aucuaaagaa     1200

guuaauucuc aauucuucag aguauacgga auagacaaac cacuagaaga aggcaaucca     1260

gacgacauau uaacaauggu aauuuacaac aguccugaag aauauaaauu aaauucagua     1320

uuauauggau acgacacaaa caauggagga auguacaucg aacccgaagg cacauucuuu     1380

accuacgaaa gagaggcuca agaaucuacu uauacucucg aagaacuuuu uaggcaugaa     1440

uauacacacu aucuccaagg uagauaugcc guaccaggac aaugggguag aacaaaacua     1500

uacgauaaug acagacuuac uugguaugaa gaaggaggcg cagaacuauu ugcgggcagc     1560

acacguacuu caggcauccu accacgaaaa uccauaguuu ccaacaucca caauacaaca     1620

agaaacaacc gauauaaauu aucagauacu guccacucaa aauacggugc guccuucgaa     1680

uuuuacaacu acgcauguau guuuauggac uacauguaua auaaagauau ggguauacuu     1740

aacaaauuga augacuuagc caaaaauaau gauguagacg gauacgauaa cuacauaaga     1800

gaccuaucau caaacuaugc auuaaaugac aaauaucaag accauaugca agaaagaauu     1860

gauaacuacg aaaacuuaac uguaccauuc guagcagaug auuacuuagu aagacaugca     1920

uauaaaaauc caaacgaaau cuacagcgaa aucagcgaag uagccaaacu caaagaugcc     1980

aaauccgaag ugaagaaauc acaauacuuc ucaacauuca cuuuaagagg uaguuacaca     2040

ggaggugcau ccaaaggaaa auuagaagac caaaaagcca ugaauaaauu uauagacgac     2100

agucuaaaga aauuagauac cuacucaugg aguggauaca aaacauuaac agccuacuuc     2160

acaaacuaca aaguagauuc aucuaaccga gucaccuacg acguaguauu ucauggcuac     2220

uuaccaaacg aaggcgauag caaaaacuca cuaccguacg gcaaaauuaa cggcacauac     2280

aaaggaacag aaaaagagaa aaucaaauuc uccuccgaag guagcuucga cccagacggu     2340

aaaaucguaa guuaugaaug ggauuucggu gacggcaaca aaucgaacga agaaaaccca     2400

gaacacagcu augauaaagu agguacauau acagucaaac uaaaaguaac cgaugauaaa     2460

ggugaaucgu cugucucaac gaccacagcc gaaauaaaag auuuguccga aaauaaauua     2520

ccagucaucu auaugcaugu cccaaaauca ggagcccuaa accaaaaagu gguuuucuau     2580

ggaaaaggaa cauacgaccc ugauggauca auagcaggcu aucaauggga uuucggugac     2640

ggcucagacu uuagcaguga acaaaaucca ucgcaugugu acacaaagaa aggagaauac     2700

acaguaacac uacgagucau ggauucuucc ggacaaauga gugagaaaac gaugaaaauu     2760

aaaauaacag acccaguaua cccaauagga acagaaaaag aaccaaauaa cuccaaagaa     2820

accgcaucug gaccaauagu ccccggaaua ccaguaagcg gcacuaucga aaauacauca     2880

gaccaagacu auuuuuacuu ugacguaaua accccaggag aaguaaaaau agacauaaau     2940

aaauuaggau acggcggcgc uacaugggua guuuacgacg aaaacaacaa ugcaguauca     3000

uacgcaacag augacggaca aaacuuaagu ggaaaauuua aagcugacaa accaggaaga     3060

uauuacauac auuuauauau guucaaugga uccuauaugc cauacagaau caacauagaa     3120

ggaagcguag gaagguaa                                                   3138


<210>  1293
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  1293
augggaacau ggauauuauu cgcaugccua cuaggagcag cauucgcaau gccacuacca       60

ccacacccag gacacccagg auacauaaac uucucauacg aaguacuaac accacuaaaa      120

ugguaccaau caauacgacc cccauaccca ucauacggau augaacccau gggaggaugg      180

cuacaccacc aaauaauacc aguacuauca caacaacauc ccccaacaca cacauuacaa      240

ccucaccacc acauaccagu aguaccagca caacaaccag uaauaccaca acaaccaaug      300

augccaguac caggacaaca cucaaugaca ccaauacaac accaccaacc aaaccuacca      360

ccaccagccc aacaaccaua ccaaccacaa ccaguacaac cacaaccaca ccaaccaaug      420

caaccacaac caccaguaca cccaaugcaa ccacuaccac cacaaccacc acuaccacca      480

auguucccaa ugcaaccacu accaccaaug cuaccagacc uaacacucga agcauggcca      540

ucaaccgaua aaacaaaaag agaagaagua gacuaa                                576


<210>  1294
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  1294
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aucaauaaga ccaccauacc caucauacgg auacgaacca      120

augggaggau gguaa                                                       135


<210>  1295
<211>  168
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001133.1__HsAMELX-LRAP

<400>  1295
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aucaauaaga ccaccaccaa ugcuaccaga ccuaacacua      120

gaagcauggc caucaacaga caaaacaaaa agagaagaag uagacuaa                   168


<210>  1296
<211>  207
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60)

<400>  1296
auggcaguaa uggcaccaag aacacuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauacau aaacuucuca      120

uacgaaguac uaacaccacu aaaaugguac caaucaauaa gaccaccaua cccaucauac      180

ggauacgaac caaugggagg augguaa                                          207


<210>  1297
<211>  240
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191)

<400>  1297
auggcaguaa uggcaccaag aacacuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauacau aaacuucuca      120

uacgaaguac uaacaccacu aaaaugguac caaucaauaa gaccaccacc aaugcuacca      180

gaccuaacac uagaagcaug gccaucaaca gacaaaacaa aaagagaaga aguagacuaa      240


<210>  1298
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  1298
augggaacau ggauacuauu cgcaugccua guaggagccg cauucgcaau gccacuacca       60

ccacauccag gacacccagg auauauaaac uucucauacg aaguauuaac accacucaaa      120

ugguaccaau ccaugauaag acccccauac ucaucauacg gauacgaacc aaugggcgga      180

uggcuacacc accaaauaau cccaguagua ucccaacaac acccacuaac acacacauua      240

caaucacacc accacauacc aguaguacca gcacaacaac caagaguaag acaacaagca      300

uuaaugccag uaccaggaca acaaucaaug acaccaacac aacaccacca accaaaccua      360

ccacuaccag cacaacaacc cuuccaaccu caaccaguac aaccacaacc acaccaacca      420

augcaaccac aaccaccagu acaaccaaug caaccacuau uaccacaacc accacuacca      480

cccauguucc cacuaagacc auuaccacca auacuaccag accuacaccu agaagccugg      540

ccagcaacag acaaaacaaa acaagaagaa gucgacuaa                             579


<210>  1299
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  1299
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aucaaugaua agaccaccau acucaucaua cggauacgaa      120

ccaaugggag gaugguaa                                                    138


<210>  1300
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001134.1__HsAMELY-LRAP

<400>  1300
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aucaaugaua agaccaccac caauacuacc agaccuacac      120

cuagaagcau ggccagcaac agacaaaaca aaacaagaag aaguagacua a               171


<210>  1301
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61)

<400>  1301
auggcaguaa uggcaccaag aacacuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauauau aaauuucuca      120

uacgaaguac uaacaccacu aaaaugguau caaucaauga uaagaccacc auacucauca      180

uacggauacg aaccaauggg aggaugguaa                                       210


<210>  1302
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192)

<400>  1302
auggcaguaa uggcaccaag aacauuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauacau aaacuucuca      120

uacgaaguac uaacaccacu aaaaugguau caaucaauga uaagaccacc accaauacua      180

ccagaccuac accuagaagc auggccagca acagacaaaa caaaacaaga agaaguagac      240

uaa                                                                    243


<210>  1303
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Sus 
       scrofa__NP_999071.1__SsAMELX-001-1

<400>  1303
augggaacau ggauacuauu cgcaugccua cuaggagcag cauucucaau gccacuacca       60

ccacacccag gacauccagg auacauaaac uucucauacg aaguacucac accauuaaaa      120

ugguaccaaa acaugauaag acacccauac acaucauacg gauacgaacc aaugggcgga      180

uggcuacacc accaaauaau accaguagua ucacaacaaa ccccacaauc acacgcauua      240

caaccacacc accauauacc aaugguacca gcacaacaac caggaauacc acaacaacca      300

augaugccac uaccaggaca acacucaaug acaccaaccc aacaccacca accaaaccua      360

ccccuacccg cacaacaacc auuccaacca caaccaguac aaccccaacc acaccaaccc      420

uuacaaccac aaucaccaau gcacccaaua caaccacuac ucccacaacc accacuacca      480

ccaauguucu caaugcaauc acuacuacca gaccuaccau uagaagcaug gccagcaaca      540

gacaaaacaa aaagagaaga aguagacuaa                                       570


<210>  1304
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Sus 
       scrofa__NP_999071.1__SsAMELX-TRAP

<400>  1304
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aaauaugaua agacacccau acacaucaua cggauacgaa      120

ccaaugggag gaugguaa                                                    138


<210>  1305
<211>  171
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Sus 
       scrofa__NP_999071.1__SsAMELX-LRAP

<400>  1305
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aaacaugaua agacacccau cacuacuacc agaccuacca      120

uuagaagcau ggccagcaac agacaaaaca aaaagagaag aaguagacua a               171


<210>  1306
<211>  210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61)

<400>  1306
auggcaguaa uggcaccaag aacauuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacau ccaggacacc caggauauau aaauuucuca      120

uacgaaguau uaacaccacu aaaaugguau caaaauauga uaagacaucc auauacauca      180

uacggauacg aaccaauggg aggaugguaa                                       210


<210>  1307
<211>  243
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Sus 
       scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189)

<400>  1307
auggcaguaa uggcaccaag aacauuagua cuacuacuau caggagcacu agcacuaaca       60

caaacauggg caaugccacu accaccacac ccaggacacc caggauacau aaacuucuca      120

uacgaaguac uaacaccacu aaaaugguac caaaacauga uaagacaccc aucacuacua      180

ccagaccuac cacuagaagc auggccagca acagacaaaa caaaaagaga agaaguagac      240

uaa                                                                    243


<210>  1308
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  1308
augggaacau ggauacuauu cgcaugccua uuaggagcag cauucucaau gccacuacca       60

ccacacccag gacacccagg auauauaaac uucucauaca uaagacaccc auacacauca      120

uacggauacg aaccaauggg aggauggcua caccaccaaa uaauuccagu aguaucacaa      180

caaacaccac aaucacacgc acuacaacca caccaccaca uaccaauggu accagcacaa      240

caaccaggaa uaccacaaca accaaugaug ccacuacccg gacaacacuc aaugacaccc      300

acacaacacc accaaccaaa ccuaccacua ccagcacaac aaccauucca accacaacca      360

guacaaccac aaccacacca accauuacaa ccacaaucac caaugcaccc aauacaacca      420

cuacuaccac aaccaccacu accacccaug uucucaaugc aaucacuacu accagaccua      480

ccacuagaag cauggccagc aacagacaaa acaaaaagag aagaaguaga cuaa            534


<210>  1309
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  1309
augggaacau ggauauucuu cgcaugccua uuaggagcau cccuagcaau gccacuacca       60

ccacacccag gacacccagg auacauaaac uucucauacg aaguacucac accauuaaaa      120

ugguaccaaa acaugauaag acacccauac acaucauacg gauacgaacc aaugggaggc      180

uggcuacacc accaaauaau accaguagua ucacaacaaa caccacaauc acacgcacua      240

caaccacauc accacauacc aaugguacca gcccaacaac caggaauacc acaacaacca      300

augaugccac uaccaggaca acacucaaug acaccaacac aacaccacca accaaaccua      360

ccacuaccag cacaacaacc auuccaacca caaccaguac aaccacaacc ccaccaacca      420

cuacaaccac aaucaccaau gcacccaauc caaccacuac uaccacaacc accacuacca      480

ccaauguucu caaugcaauc ccuacuaccc gaccuaccac uagaagccug gccagcaaca      540

gacaaaacaa aaagagaaga aguagacuaa                                       570


<210>  1310
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  1310
augggaacau ggauacuauu cgcaugccua cuaggagcag cauucucaau gccacuacca       60

ccacacccag gacacccagg auacauaaac uucucauacg aaguacuaac accacuaaaa      120

ugguaucaaa acaugauaag acacccauca cuauuaccag accuaccacu agaagcaugg      180

ccagcaacag acaaaacaaa aagagaagaa guagauuaa                             219


<210>  1311
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  1311
augggaacau ggauacuauu cgcaugccua uuaggagcag cauucucaau gccacuacca       60

ccacacccag gacacccagg auacauaaac uucucauacg aagaccuaua cuuagaagca      120

auaagaauag acagaacagc auucguacua acaccacuaa aaugguacca aaacaugaua      180

agacacccau acacaucaua cggcuacgaa ccaaugggag gauggcuaca ccaccaaaua      240

auaccagucg uaucccaaca aacaccccaa ucacacgcau uacaaccaca ccaccacaua      300

ccaauggucc cagcacaaca accagguaua ccccaacaac caaugaugcc acuaccagga      360

caacacucaa ugacaccaac acaacaccac caaccaaacc uaccacuacc agcacaacaa      420

ccauuccaac cacaaccagu acaaccacaa ccacaccaac cacuacaacc acaaucacca      480

augcacccaa uacaaccacu acuaccacaa ccaccauuac cacccauguu cucaaugcaa      540

ucacuauuac ccgaccuucc acuagaagca uggccagcaa cagacaaaac aaaaagagaa      600

gaaguagacu aa                                                          612


<210>  1312
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  1312
augggaacau ggauacucuu cgcaugccua cuaggcgcag cauucuccau gccacuacca       60

ccacacccag gacaccccgg auacauaaac uucucauacg aaguacucac accacuaaaa      120

ugguaccaaa acaugauaag acacccaaca ccacaaucac acgcacuaca accacaccac      180

cacauaccaa ugguaccugc acaacaacca ggaauaccac aacaaccaau gaugccacua      240

ccaggccaac acuccaugac acccacacaa caccaccaac caaaccuacc acuaccagcc      300

caacaaccau uccaaccaca acccguacaa ccacaaccac accaaccauu acaaccccaa      360

ucaccaaugc acccaauaca accacuacuc ccacaaccac cacuaccacc aauguucuca      420

augcaaucac uacuaccaga ccuaccacua gaagcauggc cagcaacaga caaaacaaaa      480

agagaagaag uagacuaa                                                    498


<210>  1313
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  1313
augccacuac caccacaccc aggacaccca ggauacauaa acuucucaua cgaaguacua       60

acaccacuaa aaugguacca aaacaugaua agacaccccu acacaucaua cggauacgaa      120

ccaaugggag gauggcuaca ccaccaaaua auaccaguag uaucacaaca aacaccacaa      180

ucacacgcac uacaaccaca ccaccacaua ccaaugguac cagcccaaca accaggcaua      240

ccacaacaac caaugaugcc acuaccagga caacacucaa ugacaccaac acaacaccac      300

caaccaaacc uaccacuacc agcacaacaa ccauuccaac cacaaccagu acaaccacaa      360

ccacaccaac cacuccaacc acaaucaccc augcacccca uacaaccauu acuaccacaa      420

ccaccacucc caccaauguu cuccaugcaa ucacuacuac cagaccuacc acuagaagca      480

uggccagcaa cagacaaaac aaaaagagaa gaaguagacu aa                         522


<210>  1314
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  1314
augccaggug uagcacgucu accauuauug cuagguuuau ugcuacuacc ccgaccggga       60

cgaccacuag acuuagccga uuacacauau gaccuagcag aagaggacga uagugaacca      120

uuaaacuaca aagauccaug uaaagcugcc gcauucuuag gugauauagc uuuagacgaa      180

gaagauuuac gugcauuuca aguccagcaa gcaguagauu uacguagaca uacugcacgc      240

aaaaguucaa uaaaagcagc uguaccagga aacacaucaa caccuuccug ucaaucaaca      300

aauggucaac cucaaagagg ggcuugcgga cguuggaggg ggagaaguag aaguagacgu      360

gcagcaacaa gucgaccaga acgaguaugg ccagauggag uaauuccauu uguaauuggu      420

ggaaacuuua cuggaucaca aagagcugua uucaggcaag cuaugagaca uugggaaaaa      480

cauacuugcg uuacauucuu agaacgaaca gaugaagauu ccuauauagu auuuacuuau      540

agaccuugug ggugcuguag uuaugugggu agaagagggg guggaccaca agcaauauca      600

auugguaaaa auugugacaa auuuggaaua guuguacaug aacuaggaca uguaguagga      660

uuuuggcacg aacauacaag accagauaga gacagacaug uauccauagu uagagaaaau      720

auacaaccag gacaagaaua uaauuuccua aaaauggagc cacaggaagu agagaguuug      780

ggagaaacuu acgacuucga caguauaaug cauuaugcaa gaaauacuuu uucacgagga      840

auauuccuag auacuauugu gccuaaauac gaagugaaug guguaaaacc uccaauuggu      900

caaaggacua gguuaagcaa aggagauaua gcacaagcgc gcaaacuuua uaaaugucca      960

gcauguggug aaacauuaca ggacucaaca ggaaauuuuu caucaccuga auacccuaac     1020

ggguauagug cacauaugca cuguguaugg agaauaucag uaacaccagg agagaaaaua     1080

auauuaaacu ucacuagccu ggaucuuuau agaucgagac ucuguuggua ugauuaugua     1140

gaaguuagag auggcuucug gagaaaagca ccauugagag ggcguuuuug uggcaguaaa     1200

cuaccagaac caauaguauc uacagauucc agauuauggg ucgaguucag aaguucaucc     1260

aauuggguag gaaaagguuu cuucgccgua uaugaagcga uaugcggagg ggauguaaag     1320

aaagacuaug gucauauaca aagcccuaau uauccugaug acuauaggcc aaguaaaguu     1380

uguauuugga gaauacaagu gucagaaggu uuucacguug gacucacauu ucaaucuuuu     1440

gaaauagagc gccaugacuc augugcguau gacuauuuag agguaagaga cggacauuca     1500

gaaucuucua cucuuauagg aagauauugu ggauaugaga aaccagauga uauaaaaagu     1560

acaaguucuc gacuaugguu aaaauuugua agcgauggaa gcauaaauaa agcaggauuu     1620

gcaguaaauu ucuuuaaaga aguugaugaa ugcucgagac cuaauagagg gggaugcgaa     1680

caacgauguc uaaauacacu cggaagcuac aaauguagcu gugauccagg auaugaacuu     1740

gcaccggaca aaagaagaug ugaagcugca ugcggcggau uucuaaccaa acucaaugga     1800

ucaauuacuu ccccaggaug gccuaaagaa uauccaccga auaaaaacug cauauggcaa     1860

uuaguagcuc caacacaaua ucgcaucagc uuacaauuug acuucuuuga aacugaggga     1920

aaugauguuu guaaauauga cuuugucgaa gucagaucag gccucacagc agauucuaaa     1980

uuacacggca aauuuugugg aagcgaaaaa ccggaaguaa uaacaucaca auacaauaac     2040

augagaguag aguuuaaaag cgauaauaca guaaguaaga aaggauuuaa agcacacuuc     2100

uucucagaua aagacgaaug uucaaaagac aaugggggau gucaacaaga cuguguaaau     2160

acguuuggau cauaugaaug ucaaugccga aguggauucg uacuucauga uaauaaacau     2220

gauuguaaag aagcagguug cgaucacaaa guuacaucaa cuucaggcac aauaacuuca     2280

ccuaacuggc cagauaaaua uccaucaaag aaagaaugua caugggcaau aucuucaacc     2340

ccaggucauc gcguaaaauu aacauuuaug gaaauggaua uugaaucaca accagaaugu     2400

gcauaugauc acuuagaagu auucgacgga agggaugcaa aagcaccagu auuagguaga     2460

uuuuguggca guaagaaacc agaaccaguu cuugcgacag gaagccguau guuuuuaaga     2520

uuuuacucag auaauuccgu acaaagaaaa ggauuucaag ccucccaugc gacggaaugu     2580

ggaggacaag uacgagcaga uguuaaaacc aaagaccuau acucacacgc acaauuuggu     2640

gauaauaauu acccaggugg gguagacugc gaauggguaa uaguagcaga agaaggguac     2700

ggaguugaau uaguauucca aacauuugaa guagaagaag aaaccgauug uggcuaugau     2760

uauauggaac uauucgacgg auacgacucc acagcaccga gauuaggacg auacugugga     2820

aguggaccac cagaagaagu uuauucagca ggagacucag ucuuagugaa auuucauucg     2880

gacgacacaa uaaccaagaa aggauuccac uuaagauaca cuucaacuaa auuccaagau     2940

acacuacaca guagaaaaua a                                               2961


<210>  1315
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  1315
auggucgccg gaaccagaug ccuauuagcc cuacuauuac cacaaguucu acuaggugga       60

gcugcaggau uaguaccaga acuaggaaga cgaaaauucg cggcagcauc cucaggaaga      120

ccaucaucac agccaucaga cgaaguacua uccgaauucg aacuaagguu auuaucuaug      180

uuuggauuaa aacaaagacc aacgccaucu agagacgcag ucguuccacc auacaugcua      240

gaucuauaua gaagacacuc cggacaacca ggauccccag cacccgauca uagauuagaa      300

cgagccgcau cacgugcaaa caccguaaga uccuuccacc acgaagaauc ucuagaagaa      360

cuaccagaaa caucaggaaa aacuacaaga agauucuucu uuaaccuauc aucuauccca      420

acagaagaau ucaucacauc agcagaauua caagucuuua gagaacaaau gcaagacgca      480

uuaggaaaua acucaucauu ucaccacaga auuaacauau acgaaauaau caaaccagca      540

accgcaaaca gcaaauuccc agucacucga uuacuagaua caagacuagu uaaccaaaac      600

gcaucaagau gggaaucauu ugacguaacu cccgcaguua ugagauggac agcacaagga      660

cacgcaaauc acggauuugu cguugaagua gcccauuuag aagaaaaaca aggaguuuca      720

aaaagacacg uccgcauaag cagaucacua caucaagacg aacauucuug gagucaaaua      780

agaccacuac uuguaacauu cggccacgac ggaaaaggac acccauuaca caaaagagaa      840

aaaagacaag caaaacacaa acaaagaaaa agacuaaaau caucaugcaa aagacaucca      900

uuauacguag auuucucaga uguaggaugg aacgacugga uaguagcacc accaggauac      960

cacgcauuuu acugccaugg agaaugccca uuuccacuag cagaccaccu caacucaacc     1020

aaccacgcaa uaguucaaac ccuaguaaau ucaguaaauu caaaaauacc aaaagcaugc     1080

ugugucccaa cagaacuuuc ugcaauauca augcuauauu uagaugaaaa cgaaaaagua     1140

guucuaaaaa auuaccaaga cauggucgua gaaggaugcg gauguagaua a              1191


<210>  1316
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  1316
augauaccag gaaauagaau gcucauggua guauuauuau gccaaguacu ucuaggugga       60

gcuucacaug caucacuuau accagaaacc ggaaaaaaaa aaguagcaga aauacaagga      120

caugccggag gaagaagauc cggacaauca caugaauuac uacgagauuu ugaggccacu      180

uuauuacaga uguucggauu aagaagacga ccucaaccau caaaaucagc aguaauucca      240

gacuacaugc gagaucuaua cagauuacaa ucaggagaag aagaagaaga acaaauacac      300

aguaccggac uagaauaccc agaaagacca gcaucaagag ccaauaccgu uagaucauuc      360

caccaugaag aacauuuaga aaauauacca ggaacaucag aaaauucagc uuucagauuu      420

uuauucaauu uaagcagcau accagaaaac gaagucauau caucagcaga acuaagacua      480

uuuagagaac aaguugacca aggaccugac ugggaacgcg gauuccacag aauaaauaua      540

uacgaaguaa ugaaaccacc ugcugaagua guaccaggac accuaauaac uagauuacua      600

gauacaagac uaguacacca uaauguaaca aggugggaaa cauuugacgu aucaccggca      660

guauuacggu ggacaagaga aaaacaacca aauuacggac uagcaauaga agucacacac      720

uuacaucaaa caagaacaca ucagggucaa cacguaagaa uaucacgauc acuuccacaa      780

gguucaggua acugggccca auuaagacca uuacuaguaa cauuuggaca ugacggaaga      840

ggacacgccu uaacacgaag gcgaagagcc aaaagaaguc caaaacacca uucacaaaga      900

gcacgaaaaa aaaacaaaaa uugccgaaga cauucacuau acguagacuu uucagauguc      960

ggauggaaug acuggaucgu agcaccacca ggcuaccaag cauuuuacug ucacggagau     1020

ugcccauuuc cacuagcaga ucacuuaaac ucaaccaauc acgcaauagu acaaacacua     1080

guaaauucug uaaacagcuc uauaccaaaa gcuuguugug uaccaacaga acuaucagcc     1140

auaucuaugu uauaucuaga ugaauaugau aaaguaguau uaaaaaacua ucaagaaaug     1200

gucguagaag gaugcggaug uagauaa                                         1227


<210>  1317
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  1317
augcccggau uaggaagacg agcacaaugg cuaugcuggu ggugggguuu auuauguagc       60

uguugcgguc caccaccuuu aagaccacca uuaccagccg cagcugcugc ugcagcaggc      120

ggucaacuau uaggagaugg gggaucaccc gggagaacag aacaaccccc accaucaccc      180

caaagcucau caggguucuu auacagaaga uuaaaaacac aagaaaaacg cgaaaugcaa      240

aaagaaauac uaaguguauu aggauugcca cauagaccua gaccauuaca uggauuacaa      300

caaccacaac cuccagcuuu aagacaacaa gaagaacaac aacaacaaca acaauuaccc      360

agaggagaac cacccccagg aagacuaaaa ucugcuccau uauucaugcu agaccuauac      420

aaugcacuaa gcgcagacaa ugacgaagau ggagcuucug aaggagaaag acaacaauca      480

uggccucaug aagcagcuuc aagcagucaa aggagacaac caccaccagg agcagcacac      540

ccacuuaauc gaaaaagccu acuagcaccc ggcucuggau caggaggcgc aaguccauua      600

acaucagcac aagauagcgc guuuuuaaau gacgcagaca ugguaauguc auucgugaau      660

uuaguagaau acgauaaaga auuuucucca agacaaagac accacaaaga guucaaauuc      720

aaucuauccc aaauaccuga aggagaagua guaacugcag cagaauuuag aaucuacaaa      780

gacuguguaa ugggaucauu caaaaaucaa acuuucuuaa uaucuaucua ccaaguauua      840

caagaacauc aacauagaga cucugauuua uuccucuuag acacaagagu uguaugggca      900

ucagaagaag guuggcuaga auuugacauu acugcaacau caaacuuaug gguaguaaca      960

ccacaacaua acaugggacu acaauuauca gucguaacca gagauggugu ucauguacac     1020

ccuagagcug caggacuugu aggcagagac ggaccauacg auaaacaacc auucauggua     1080

gcauucuuca aaguaucaga aguacaugua agaacaacac gaucugcuag cucaagaaga     1140

agacaacaaa gucgcaacag aucuacacaa ucacaagaug uagcacgagu aucaucugcu     1200

ucagacuaua acuccuccga acuaaaaaca gcaugcagga aacacgaauu auacguuucc     1260

uuccaagauu uaggauggca agacuggaua auagcaccca aaggauacgc ugcaaacuac     1320

ugcgacggug aauguucauu uccauuaaau gcacauauga acgcaacaaa ccaugcaauc     1380

guacaaacuc uaguacaccu aaugaaucca gaauaugucc ccaaaccaug uugcgcaccc     1440

acaaaacuua acgcaauauc agucuuauac uuugacgaca auucaaaugu aauccuaaag     1500

aaauauagaa acaugguagu cagagccugc gguugccauu aa                        1542


<210>  1318
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  1318
augcauguaa gaucacuaag agcagcugcc ccacacucau uuguagcacu gugggcacca       60

cuuuuuuuac uaagaagcgc auuagcagac uuuucacuag acaaugaagu acauucaagc      120

uuuauucaua ggagacuucg gucacaagaa agacgugaaa ugcaaagaga aauauuaucu      180

auucuaggac uaccacaccg cccaagacca caucuacaag gaaaacacaa uucagcucca      240

auguucaugc uagaucuuua uaacgcaaug gcagucgaag aaggaggagg ccccggagga      300

caaggauuuu ccuauccaua uaaagcagua uuuucaacac aaggaccucc ucuagcaagu      360

cuacaagauu cacauuucuu aacagaugca gauaugguaa ugucauuugu aaauuuagua      420

gaacaugaua aagaauuuuu ucacccacgu uaccaccaua gagaauucag auucgaucua      480

ucuaaaauac cagaagguga agcaguaaca gcagcugaau ucagaauaua caaagauuac      540

auacgagaaa gauuugacaa cgaaacauuc agaauaucag uauaucaagu acuacaagaa      600

cacuuaggua gagaaagcga ucuauuucua uuagacucca gaacacucug ggcaucagaa      660

gaaggcuggc uaguauucga uauaacagca accaguaauc acugggucgu aaacccaaga      720

cacaaccucg gacuacaauu aucaguagaa acauuagacg gccaaaguau uaacccaaaa      780

cucgcaggac uaauaggaag acacggacca caaaacaaac aaccauucau gguagcauuc      840

uuuaaagcaa ccgaaguaca cuucagauca auacgaucaa caggauccaa acaaagaagc      900

caaaauagau caaaaacucc aaaaaaucaa gaagcauuaa gaauggcaaa uguagcugaa      960

aauucaucaa gugaucaaag acaagccugc aaaaaacacg aauuauacgu auccuuccga     1020

gauuuaggau ggcaagacug gauaauagca ccugaaggcu acgccgcaua cuacugugaa     1080

ggagaaugug cauuucccuu aaacucauau augaacgcaa cuaaucacgc uauaguacaa     1140

acacuaguac acuuuauaaa ucccgaaaca guacccaaac caugcugcgc accaacacaa     1200

cucaacgcua uaucaguauu auauuuugac gacucuucua acguuauccu aaaaaaauau     1260

cgaaauaugg uagucagagc auguggcugc cacuga                               1296


<210>  1319
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  1319
augaaagcau cagcagcacu acuaugccua cuacuaacag cagcagcauu cucaccacaa       60

ggacuagcac aaccaguagg aauaaacaca ucaacaacau gcugcuacag auucauaaac      120

aaaaaaauac caaaacaaag acuagaauca uacagaagaa caacaucauc acacugccca      180

agagaagcag uaauauucaa aacaaaacua gacaaagaaa uaugcgcaga cccaacacaa      240

aaauggguac aagacuucau gaaacaccua gacaaaaaaa cacaaacacc aaaacuauaa      300


<210>  1320
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  1320
auguugcuua cuuuaauaau auuacuucca guugucagua aauuuucguu ugugucauua       60

ucugcaccac aacauuggag uuguccagaa gguacgcuag caggcaacgg uaauucuacg      120

ugugucgguc cagcgccauu ucuaaucuuu ucucauggua acuccauuuu uagaauagau      180

acagaaggua caaauuacga acaauuagua guugacgcag gagucagcgu aauaauggac      240

uuucauuaua augagaaaag aaucuauugg guagacuugg aaagacaauu acuucagcgu      300

guauucuuga auggauccag acaagaaaga guauguaaua uagagaaaaa uguaucaggu      360

auggcuauaa acuggauaaa ugaagaagug auuuggucaa aucaacaaga agggaucauu      420

accguuacag acaugaaagg aaauaauucc cacauacuac uaucagcacu aaaauauccc      480

gccaauguug caguagaucc aguggaaaga uuuauauuuu gguccucaga aguagcagga      540

ucauuauaua gagcagacuu agacggugug gguguuaagg cuuuacuaga aacuucugag      600

aaaauuaccg caguaaguuu agacguuuua gacaaaagau uauuuuggau ucaauauaau      660

agggaagguu caaauucacu uauauguucu ugcgacuaug augguggauc agugcauaua      720

aguaaacauc caacgcaaca caaucucuuu gcaaugucuu uauuugguga uagaauauuu      780

uacagcacuu ggaaaaugaa aacaauaugg auagccaaca aacauaccgg aaaagauaug      840

guaaggauaa aucuacacag uuccuucguu ccuuuaggug aacuaaaagu aguacaucca      900

cuagcgcaac cuaaagcgga agaugacacu ugggaaccag aacaaaaacu auguaaguua      960

cgaaaaggca acuguucauc uacagugugc gggcaagacu uacaaaguca cuuauguaug     1020

ugcgcggaag gcuaugcgcu caguagagau agaaaauauu gugaagaugu aaaugaaugu     1080

gcauuuugga accauggaug uacacuagga ugcaaaaaua caccagguuc auauuauugu     1140

acuugucccg uuggauuugu ccuguuacca gacggcaaaa ggugccauca gcuaguaagu     1200

uguccacgua auguuucaga auguagccac gauuguguuu ugacaaguga aggaccacua     1260

ugcuuuugcc cagaaggauc aguauuagaa agggauggaa aaacauguag ugguuguagu     1320

ucaccagaua auggagguug uagucaacuu uguguuccau uaucuccugu aucuugggaa     1380

ugcgauuguu ucccagguua ugauuuacaa uuagaugaga aaaguugugc agcgucuggc     1440

ccacaaccau ucuuacucuu ugcaaauuca caagauauaa gacacaugca uuucgauggc     1500

accgacuacg gcacccuauu aagucaacaa auggggaugg uauaugcacu ugaccaugau     1560

ccaguagaaa acaaaauaua cuucgcacau accgcacuca aauggaucga aagagcaaau     1620

auggacggaa gucaaaggga acgguugauu gaagaaggag uagauguacc ugaggguuua     1680

gcaguugauu ggauagggag gagauuuuau uggacggaca gggggaaaag uuuaauagga     1740

cgaagcgacc ucaacgggaa aagaagcaaa auaaucacua aagaaaauau uucacaacca     1800

agaggaauug cuguacaucc aauggcaaaa cgucuauuuu ggacagacac aggaauaaau     1860

ccuagaauag aguccaguuc acugcaagga uuggggagau uagugaucgc caguuccgac     1920

cuaauauggc caucgggaau uacaauagac uuuuuaaccg auaaacuaua uuggugcgau     1980

gcaaaacagu caguaauuga aauggccaau cuagauggau cuaaaagaag aagacuaaca     2040

caaaaugaug ugggacaccc auuugcuguu gccguuuucg aggacuacgu cugguuuuca     2100

gauugggcaa ugccaagugu caugagaguc aauaagagaa cugguaagga uagagucaga     2160

uuacaaggcu caauguuaaa accaucgagu cuagucguag uccacccauu agcaaaacca     2220

ggugcagauc ccugcuuaua ucaaaaugga gggugcgaac acauauguaa gaaaagacuu     2280

ggcacagcau gguguucaug uagagaagga uuuaugaagg cuucagaugg aaaaaccugu     2340

uuagcauuag auggccauca acuucucgcc ggaggagaag uugacuugaa aaaccaagua     2400

acaccccuag auauauuaag caaaacaaga guuagcgaag auaacauaac agaaucucaa     2460

cauauguuag uagcagaaau uauggucuca gaucaagaug acugcgcacc uguaggaugu     2520

ucuauguaug cuagaugcau aucagagggg gaagaugcga caugucaaug cuuaaaagga     2580

uuugcaggcg acggaaaauu augcucagac auagacgaau gugaaauggg aguuccuguu     2640

uguccuccag caucuuccaa auguauaaau accgaaggug guuauguaug uagauguagu     2700

gaaggauacc aaggggacgg uauccauugu uuagauauag augaaugcca auugggagaa     2760

cacuccugug gagagaacgc auccuguaca aauacugaag gagguuauac guguaugugc     2820

gcaggaaggc uuuccgaacc ugguuuaauu ugcccagauu caacaccucc cccacaccuu     2880

cgugaagaug accaccauua uaguguacga aauucagauu cugagugccc acuaagccau     2940

gauggauauu guuuacacga uggaguaugc auguacauag aagcguugga uaaauacgcu     3000

uguaauugug ugguuggaua cauaggugaa agaugucaau accgagaccu aaaauggugg     3060

gaacuaagac augccgggca cggacaacaa caaaaaguaa uagucguugc agugugugua     3120

guagucuuag ucaugcuauu acuauugagc cucuggggug cacacuauua uaggacacaa     3180

aaacuacuau cuaaaaaccc caaaaaucca uaugaagaau caagucguga ugucagauca     3240

agaagaccag cagacacaga agacggaaug ucaucguguc cacaaccaug guuuguggua     3300

auuaaagaac aucaagaucu caaaaacgga ggccaacccg uugcugguga agauggacaa     3360

gcagcagaug guaguaugca gcccacauca uggcgacaag agccacaauu augcggcaug     3420

ggaacagaac aagguuguug gauuccaguu aguucugaca aaggaagcug uccgcaagug     3480

auggagaggu cauuucauau gccaagcuac ggaacacaga cacucgaagg cggaguagag     3540

aaaccacauu cgcuucuuuc ugcaaaccca uuauggcaac aaagagcucu agauccaccu     3600

caccaaaugg aauugacuca auaa                                            3624


<210>  1321
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  1321
augacagcag gcagaagaau ggaaaugcua ugugcaggac gaguaccagc auuauuacua       60

ugucuaggau uccauuuauu acaagcagua cuaagcacaa caguaauacc aagcuguaua      120

ccaggagaaa gcucagacaa uugcacagcc uuaguacaaa cagaagacaa uccaagagua      180

gcacaaguaa guauaacaaa augcucaagc gauaugaaug gauauugcuu acacggacaa      240

uguauauauc uaguagacau gagccaaaac uauugcagau gcgaagucgg auacacagga      300

guaagaugug aacauuucuu cuuaacagua caucaaccac uaucaaaaga auacguagca      360

uuaacaguaa uauuaauaau acuauuucua auaacaguag uaggaagcac auacuauuuc      420

uguagauggu acagaaacag aaaaucgaaa gaaccaaaaa aagaauacga acgaguaaca      480

ucaggagauc cagaacuacc acaaguauaa                                       510


<210>  1322
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  1322
auggcagaag gagaaauaac aacauucaca gcacuaacag aaaaauucaa ccuaccacca       60

ggaaacuaca aaaaaccaaa acuacuauac ugcucaaacg gaggacacuu ccuaagaaua      120

cuaccagacg gcacaguaga cggaacaaga gacagauccg accaacacau acaacuacaa      180

cuaucagcag aaucaguagg agaaguauac auaaaaucaa cagaaacagg acaauaccua      240

gcaauggaca cagacggacu acuauacgga ucacaaacac caaacgaaga augccuauuc      300

cuagaaagac uagaagaaaa ccacuacaac acauacauau caaaaaaaca cgcagaaaaa      360

aacugguucg uaggacuaaa aaaaaacgga agcugcaaaa gaggaccaag aacacacuac      420

ggacaaaaag ccauacuauu ccuaccacua ccaguaucau cagacuaa                   468


<210>  1323
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  1323
augguaggag uaggaggggg agauguagaa gauguaacac caagaccagg uggaugucaa       60

auuagcggaa gaggugcaag aggauguaau ggaauaccag gagcagcagc uugggaagca      120

gcauuaccga gaagacgacc gagaagacau ccgaguguga auccaagauc aagagcagcu      180

ggaagcccaa gaacaagagg aagaagaaca gaagaaagac caaguggaag cagauuagga      240

gauagaggaa gaggacgagc auuaccagga ggaagauuag gaggaagagg aagaggaaga      300

gcaccagaga gaguaggagg gagaggaaga ggaagaggaa cagcagcgcc aagagcagca      360

ccagcagcaa gaggaucaag accaggacca gcaggaacaa uggcagcggg aaguauaaca      420

acauuaccag cucuaccaga agauggagga aguggggcgu uuccaccagg acauuuuaaa      480

gauccaaaaa gauuauauug uaaaaaugga ggauuuuuuu uaagaauaca uccagaugga      540

agaguagaug ggguaagaga aaaaucagau ccacauauaa aauuacaauu acaagcggaa      600

gaaagaggag ugguaaguau uaaaggaguu ugugcaaaua gauauuuggc gaugaaagaa      660

gaugggaggu uauuagcaag uaaaugugua acggaugaau guuuuuuuuu ugaaagacua      720

gaaagcaaua acuauaacac auauagaucg agaaaauaca caucauggua uguagcauua      780

aaaagaacag gacaauauaa acuaggaagu aaaacaggac caggacaaaa agcaauauua      840

uuuuuaccaa ugagugcaaa gaguuaa                                          867


<210>  1324
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  1324
augcacaaau ggauacuaac auggauacua ccaacacuac uauacagaag cugcuuccac       60

auaauaugcc uaguaggaac aauaucacua gcaugcaacg acaugacacc agaacaaaug      120

gcaacaaacg uaaacugcuc aucuccagaa agacacacaa gaucauacga cuacauggaa      180

ggaggagaca uaagaguaag aagacuauuc ugcagaacac aaugguaccu aagaauagac      240

aaaagaggaa aaguaaaagg aacacaagaa augaaaaaca acuacaacau aauggaaaua      300

agaacaguag caguaggaau aguagcaauc aaaggaguag aaucagaauu cuaccuagca      360

augaacaaag aaggcaaacu auacgcaaaa aaagaaugca acgaagacug caacuucaaa      420

gaacuaauac uagaaaacca cuacaacaca uaugcaagcg caaaauggac acacaacgga      480

ggagaaaugu ucguagcauu aaaccaaaaa ggaauaccag uaagaggaaa aaaaacaaaa      540

aaagaacaaa aaacagcaca cuuccuacca auggcaauaa cauaa                      585


<210>  1325
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  1325
augaaauuau uaccaucagu aguacuaaaa cuauuucuag cagcaguacu aucagcauua       60

guaacaggag aaagccuaga aagacuaaga agaggacuag cagcaggaac cucaaaccca      120

gacccaccaa caguaucaac agaucaauua cuaccacuag gcggaggaag agauagaaaa      180

guaagagacu uacaagaagc agaccuagau uuacuaagag uaacauuauc aucaaaacca      240

caagcacuag caacaccaaa caaagaagaa cacggaaaaa gaaaaaaaaa aggaaaagga      300

uuaggaaaaa aacgagaucc augccuaaga aaauauaaag acuucugcau acauggagaa      360

ugcaaauacg ucaaagaacu cagagcacca agcugcauau gucacccugg auaccacgga      420

gaaagaugcc acggacuaag ucuuccagua gaaaacagau uauacacaua cgaccacaca      480

acaauacuag caguaguagc aguaguauua agcucaguau gucuauuagu aauaguaggu      540

cuacuaaugu ucagauauca ccgaagagga ggauacgaug uagaaaauga agaaaaagua      600

aaacuaggaa ugacaaauag ccacuaa                                          627


<210>  1326
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  1326
auguggguaa cuaaacuauu accagcauua cuauuacaac auguccuacu acaccuacua       60

uuacuaccua uugcaauacc auacgccgaa ggucaaagaa aacgaagaaa uacaauacau      120

gaguucaaaa agucagcaaa aacaacauua aucaaaauag acccagcacu aaaaauaaaa      180

acaaagaaag uaaauacagc agaucaaugu gcaaacagau gcacuagaaa caaaggacua      240

ccauuuacau guaaagcauu cguauuugau aaagcaagaa aacaaugucu augguuucca      300

uuuaauagca ugaguucagg aguaaagaaa gaguucggac augaauuuga ccuauaugaa      360

aauaaagacu auauaagaaa uugcauaaua gguaaaggaa gaucauauaa aggaacaguu      420

uccaucacaa aaucaggaau aaaaugucaa cccuggucau caaugauacc acacgaacau      480

agcuuucuac caagcucaua cagagguaaa gaucuacaag aaaauuauug uagaaauccg      540

agaggugaag aaggcggacc augguguuuu acuucuaauc cagaaguacg auaugaagua      600

ugugauauac cgcaaugcuc agaaguagaa uguaugacau guaacggaga aucauauaga      660

gguuugaugg aucauacaga aucaggcaaa auaugucaaa ggugggacca ccaaacucca      720

caucgacaua aauuucuacc agaacguuau ccagauaaag gcuuugauga uaauuacugu      780

cgaaacccag acggacaacc aagaccuugg ugcuacacau uagaucccca uacucgaugg      840

gaauacugug caauaaaaac augcgcagau aacacaauga augacacaga uguuccucua      900

gaaacuacug aaugcauaca aggacaagga gaaggauacc gaggaacugu aaauacaaua      960

uggaauggaa uaccuuguca aagaugggau ucacaauauc cucaugaaca ugacaugacc     1020

ccagaaaauu uuaaaugcaa agaucuaaga gaaaauuauu gcagaaaccc agacggaucu     1080

gaaucgccau gguguuuuac aacugauccu aacauaagag uaggcuauug cucucagaua     1140

ccgaauugcg acaugagcca uggacaagac uguuauagag gaaauggcaa aaauuacaug     1200

ggaaaucuca gucaaacaag aucaggauua acuuguucaa ugugggacaa aaauauggaa     1260

gauuuacaua gacacauauu cugggaacca gacgcaucaa aauuaaauga aaacuauugc     1320

agaaauccag augacgacgc acacgggcca ugguguuaua caggaaaucc auuaauacca     1380

ugggacuacu guccuauaag ccgaugugaa ggagauacaa cucccacaau uguaaacuua     1440

gaucauccag uaaucucaug ugccaaaaca aaacaauuaa gagucguaaa cgguauaccu     1500

acuaggacaa acauaggcug gaugguguca cuuagauaua gaaauaaaca cauaugcgga     1560

ggcagucuua uaaaagaauc auggguccuc acagcaagac aauguuuucc cagcagagau     1620

uuaaaggacu augaagcaug guuaggaaua cacgauguac acggacgagg agacgaaaaa     1680

uguaaacaag uacuaaaugu uucucagcua gucuauggac cagaagggag cgauuuaguc     1740

uuaaugaaac uagcaagacc ggcagucuua gacgacuucg uaucuacaau ugauuuaccu     1800

aacuacggau gcacgauacc agaaaagacu agcuguucug uuuauggaug ggguuauacu     1860

ggacuaauca acuacgacgg acuauuaagg guggcacauu uauauauuau gggaaacgaa     1920

aaauguucuc aacaccacag aggaaaagua acauuaaacg aaucagaaau augcgcagga     1980

gcagagaaaa ucggaucagg cccgugugaa ggagacuaug gugggccgcu agugugcgaa     2040

caacacaaaa ugcgaauggu auuaggggua auaguaccug gacggggaug cgccauacca     2100

aauagaccag gaauauucgu aagaguagca uauuaugcca aauggauaca uaaaauaaua     2160

cuaacauaua aaguaccaca aucuuaa                                         2187


<210>  1327
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  1327
auggccaaag cagcugcaau aggaauagau cuaggaacaa cauacuccug uguaggagua       60

uuccaacacg gaaaaguaga aauaaucgca aaugaucaag guaacagaac aacaccauca      120

uacguugcau uuacagacac agaaagauua auaggagaug cagccaaaaa ccaagucgca      180

cuaaauccac aaaacacagu auuugaugca aaacgcuuaa uaggaagaaa auuuggcgau      240

ccaguaguac aaucagacau gaaacauugg ccauuucagg uaauaaacga uggagauaaa      300

ccaaaaguuc aaguuaguua caaaggcgaa acuaaagcau uuuacccgga agagauauca      360

agcaugguau uaacaaaaau gaaagaaauc gcagaggcuu auuuaggaua cccaguaaca      420

aacgcaguaa uaacaguacc agcuuacuuu aaugauaguc agagacaagc aacuaaagau      480

gccggaguaa uugccggacu aaacguacua agaauaauaa acgaaccaac ugcagcagca      540

auagcauaug gauuagauag aacaggcaaa ggagaaagaa auguauuaau auucgaccua      600

ggaggaggua cauucgacgu gucaauauua acaauugaug auggaauauu cgaaguaaaa      660

gcaacagccg gggacacaca uuuaggggga gaagauuuug acaacagacu gguaaaccau      720

uuuguagaag aauuuaaaag aaaacacaag aaagacauuu cacaaaauaa aagggcaguu      780

agaagacuaa gaacugcaug ugagagggca aaaaggacgu uaagcaguag uacccaagca      840

ucacuagaga uagacucauu auuugaagga auugauuuuu auacuucaau cacgagagcg      900

agauuugaag aauuauguag ugaucucuuu agaucgacau uagaaccugu cgaaaaagca      960

cuaagagaug cgaaacuaga caaagcacaa auacaugacu uaguucuagu aggaggauca     1020

accagaauac caaaaguaca aaaacuacua caagauuucu ucaacggaag ggacuuaaau     1080

aaaucaauaa acccagauga agcugucgcu uacggugcag cuguccaagc agcaauacua     1140

augggagaua aaagcgagaa ugugcaagac uuauuauuau uagacguugc accucuaucg     1200

cuaggacuag aaacagcagg aggaguaaug acagcacuua uaaaaagaaa cagcacaaua     1260

ccgacuaaac aaacgcaaau auuuacaacc uauucagaua accaaccugg cguccuuaua     1320

cagguuuaug aaggugaaag agcaaugaca aaagauaaca aucuacuagg aagauuugag     1380

cuaaguggaa uaccaccagc accucgagga guaccacaaa uagaaguuac auucgacaua     1440

gacgcuaaug gcauucuaaa ugugacagcu acugacaaaa guaccggaaa agcaaauaaa     1500

auaacuauua caaacgauaa aggaagacua agcaaggaag agauagaacg caugguacag     1560

gaagcagaaa aauacaaagc ggaagacgag guccagcgag aaagaguaag cgcuaaaaac     1620

gcauuagaau cauaugcauu caacaugaaa agcgcaguag aagaugaagg acuaaaaggu     1680

aaaauaagcg aagcagauaa aaagaaagua cuagauaaau gucaagaagu uauaaguugg     1740

uuagaugcaa auacuuuagc ggaaaaagau gaauuugaac auaaaagaaa agaacuagaa     1800

cagguaugca auccuauuau aucaggauua uaccaaggag cuggaggacc aggaccagga     1860

ggcuucggag cacaaggacc gaaaggagga uccggaucag ggccaacaau agaagaagua     1920

gauuaa                                                                1926


<210>  1328
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  1328
auggcaaaag cugcagcaau aggaauagac cuaggaacaa cauacuccug cguaggagua       60

uuucagcaug guaaaguuga aauaauagcu aacgaccaag gcaacagaac aacccccuca      120

uacgucgcau ucacagauac cgaaagauua aucggagaug cggcuaaaaa ccaaguggca      180

cucaauccac aaaacacagu auuugacgca aaaagacuga uaggaagaaa auucggcgau      240

ccagugguuc aaucagauau gaaacauugg ccauuccagg uaauaaauga uggagauaaa      300

ccaaaaguac aaguaucaua uaaaggagaa acaaaagcau uuuauccaga ggaaauaagu      360

aguaugguau uaacaaaaau gaaagaaaua gcugaagcau aucucggaua cccaguaaca      420

aacgccguaa uaacaguucc agcauauuuc aacgacaguc aaagacaagc aacaaaagau      480

gcaggaguaa uagcuggccu aaauguacuu agaauaauaa augaaccuac ugcugcugcc      540

auagcauacg gacuagaucg aacaggcaaa ggagaaagaa auguuuuaau auucgaccuu      600

ggaggaggaa cauucgacgu aagcauuuua acaauagaug auggaauauu ugaaguuaaa      660

gccacugcag gggauacuca ccuaggagga gaagauuucg auaacaggcu aguuaaucau      720

uuuguagaag aauuuaaaag aaaacauaag aaagacauaa gucaaaacaa aagagcagua      780

agaagauuga gaacagcaug ugaaagagcu aaaagaacgc uaagcucaag cacacaagca      840

aguuuagaaa uagauaguuu auuugaagga auagauuuuu auacuucgau aacgagagca      900

agauuugaag aauuauguuc agauuuauuu agaucaacgu uagaaccagu ugaaaaagca      960

cuaagagacg caaaauuaga uaaagcucaa auacaugacc uagucuuggu cggaggcuca     1020

acacgaaucc cuaaaguaca aaaauuacuu caagauuucu uuaacgguag agaucuaaau     1080

aaaucaauaa aucccgacga agcuguagca uauggagcag cuguacaagc cgcaauucuu     1140

augggagaua aaucagaaaa uguacaagau uugcuacuuu uagacguggc accacuuagc     1200

cuaggacuag aaacagcugg aggaguaaug accgcauuaa uaaaacgcaa cucgacuaua     1260

ccaacaaaac aaacacaaau cuuuacaaca uacagugaua aucaaccagg aguacuaaua     1320

caaguauaug aaggagaaag agcaaugacu aaagacaaua aucuacuagg acgguucgaa     1380

cuaagcggca uuccaccagc accucgagga guaccacaaa uugaaguaac auuugauaua     1440

gacgcaaacg ggauauuaaa cguuacagca accgauaaaa gcacaggcaa agcaaacaaa     1500

auaacaauua caaaugauaa aggaagacuu ucaaaagaag aaauagagag aaugguacaa     1560

gaagcugaga aauacaaagc cgaagacgaa guccaaagag aaagaguuag cgcuaaaaac     1620

gcacuggaau cauaugcuuu caauaugaaa ucagcaguag aggacgaagg acuaaaaggc     1680

aaaauuucag aagcagacaa aaagaaagua cuagauaaau gucaagaagu aauuagcugg     1740

uuagaugcaa auacccuggc agagaaagau gaauuugaac auaaaagaaa agaauuagaa     1800

caaguaugca aucccauaau aucaggucug uaucaaggag caggcgggcc aggaccagga     1860

ggauuuggag cacagggacc aaaaggugga uccgguagcg gcccaacaau cgaagaagua     1920

gauuaa                                                                1926


<210>  1329
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  1329
auggcaacag caaaaggaau agcaauagga auagacuuag ggacaacuua caguuguguu       60

ggaguauuuc agcacgggaa agucgaaaua auagcaaacg aucaagguaa uaggaccacc      120

ccuucguacg uagcauuuac agauacugaa agacuaauag gugaugcagc gaaaaaccaa      180

gucgcaauga acccgcaaaa uacaguauuu gacgcaaaac gguuaauugg aagaaaguuu      240

aacgacccag uuguacaagc agauaugaaa uuauggccau uccaaguaau aaacgaagga      300

ggaaaaccua aaguguuggu auccuauaaa ggcgaaaaca aagcauuuua uccggaagaa      360

auaucaucaa ugguacuaac aaaacuuaaa gaaacggcag aagcauuucu aggacaucca      420

gucacaaacg caguaauaac aguuccagca uacuuuaacg auagucaaag acaagcaacg      480

aaagaugcag gaguuauagc aggucuaaau guacuuagga uaaucaacga accaacggca      540

gcagcaauag cauacggacu agauaaagga ggacaaggag aaagacaugu acuaauauuu      600

gauuuaggcg gaggaacauu cgacguaagu auauuaacca uagaugaugg aauauucgaa      660

guaaaagcaa cagcagggga cacacacuua ggaggcgaag acuucgauaa caggcuagua      720

agccauuuug uagaagaguu caaaagaaaa cacaagaaag auauaucaca aaauaaacgc      780

gcaguacgaa gacucagaac agcuugcgaa agggcaaaaa gaaccuuaag cucuaguaca      840

caagcaaacc uggaaaucga uaguuuauac gaaggaauag auuucuauac aucaaucacu      900

agagcuagau uugaagaacu cugugcagau cuauuuagag gaacauuaga acccguagaa      960

aaagcgcuua gagacgccaa aauggacaaa gcaaaaauac augacauagu ccuaguaggu     1020

ggaaguacgc guauaccaaa aguacaaaga uuauuacagg auuauuucaa cggaagagau     1080

cuuaacaaaa guauaaaucc cgaugaagca guagcauacg gugcagcagu acaggcagca     1140

auacuaaugg gagauaaauc ugaaaaagua caagacuuac uacuguuaga cguagcacca     1200

cuuucacuag gacuagaaac agcuggaggu guaaugacag cauuaauaaa aagaaauuca     1260

acuauaccaa cuaaacaaac acaaauauuu acaaccuaua gugacaauca accaggagua     1320

cuaauacaag uauaugaagg agaaagagca augacaaaag auaacaaucu gcuaggaaga     1380

uuugaucuaa cgggaauacc accagcacca agaggaguac cacaaauaga aguaacguuu     1440

gacauugaug caaauggaau acuaaacgug accgccacag auaaaaguac uggaaaaguc     1500

aauaaaauaa cuaucacaaa cgauaaaggg agacuaagca aagaagagau agaaagaaug     1560

guuuuagaug cagaaaaaua caaagcagaa gacgagguac aaagagagaa aauagcagcu     1620

aaaaaugcau uagaaucaua ugcauuuaau augaaaagcg uaguaucaga cgaaggauua     1680

aaaggaaaaa uaagcgaaag ugauaaaaac aaaauacuag acaaaugcaa ugaacuauua     1740

ucaugguuag aaguaaauca gcuagcagaa aaagaugaau uugaccauaa aagaaaggaa     1800

cuagaacaaa uguguaaucc aauaauaaca aaauuauacc aaggggguug cacaggaccu     1860

gcauguggaa caggauaugu cccaggcaga ccagcaacag gaccaacgau cgaagaagug     1920

gauuaa                                                                1926


<210>  1330
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  1330
augucagcac gugggcccgc gauagguaua gaucuaggga caacauacag cugcguuggg       60

guguuucaac acggaaaagu agaaauaaua gcaaaugauc aagguaacag aaccacacca      120

aguuacguug cauuuacaga uacugaaagg uuaauaggag acgcagcgaa aaaccaagua      180

gccaugaacc caacaaauac gaucuuugac gcaaaacguc uuauaggacg uaaauuugag      240

gacgcgaccg uccaaagcga uaugaaacac uggccauuua gaguaguaag cgaaggagga      300

aaacccaagg uacaaguaga auacaaagga gaaacaaaaa ccuuuuuccc ugaagaaaua      360

ucaucaaugg uauuaacaaa aaugaaagaa auagcagaag ccuaccuugg gggaaaaguc      420

cacucagcag uaauaacggu accagcauac uuuaacgaua gccagagaca agccacaaaa      480

gaugcaggga caauaacagg acucaaugua uuaagaauaa uuaaugagcc uacagcagca      540

gcaauagcau auggauuaga uaagaaagga ugugcgggug gggaaaagaa cguauuaaua      600

uuugaccuag guggaggaac auucgacgua aguauacuaa caauagaaga uggaaucuuc      660

gaagugaaaa guacagcagg agauacucac cugggcggag aagauuuuga uaaucgaaug      720

guuucacauu uagcagaaga guucaaacga aagcacaaga aagauauagg accaaacaaa      780

agagcaguac gaagauugcg aacagcgugc gaaagagcga aaagaacacu gaguucauca      840

acacaagcga gcauagaaau agacucacuu uaugaaggag uagauuuuua uacaaguaua      900

acacgcgcaa gauuugaaga guuaaaugca gauuuauuca gaggaacguu agaaccgguu      960

gagaaagcac uaagagacgc aaaacuugac aaaggccaaa uacaagaaau aguauuaguc     1020

ggcggaucaa cuagaauacc aaaaauacaa aaacuacugc aagacuucuu uaauggaaaa     1080

gaacucaaca aaagcauaaa uccagacgaa gcagucgcau auggugcagc aguacaagca     1140

gcaauauuaa uaggggauaa aucagaaaac gugcaagauc uacuguuacu agaugucaca     1200

ccacuaucac uagguauaga aacagcaggg gguguaauga caccucuaau aaaaagaaau     1260

acaaccauuc caacaaaaca aacacaaaca uuuacaaccu acucagauaa ucaaucaagc     1320

guucuaguac aaguauauga aggugaaaga gcaaugacga aggauaauaa uuuauuagga     1380

aaauucgauc ucacagguau accaccagcg ccccgaggag uaccacaaau ugaaguaacu     1440

uuugacauag augcaaacgg aaucuuaaau guuacagcag cagauaaaag caccggaaaa     1500

gaaaauaaaa ucacuauaac gaaugauaaa ggaagauuaa gcaaagauga uauagauaga     1560

augguacaag aagcggaaag auacaaaagu gaagacgaag caaauagaga uagaguggca     1620

gccaaaaaug cacuagaaag cuauacauau aauaucaaac aaacagucga agaugaaaaa     1680

cuaagaggaa agauaucaga acaagauaaa aacaaaauau uggacaaaug ucaagaggua     1740

auaaacuggu uagauagaaa ucaaauggcu gaaaaggaug aauaugaaca uaaacaaaaa     1800

gaauuagaaa gaguaugcaa uccuauaaua ucaaaacuau aucaaggagg accaggagga     1860

ggaagcggag gaggaggaag cggcgcauca gguggaccaa ccauagagga aguagauuaa     1920


<210>  1331
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  1331
augaguguug uugguauuga uuuaggcuuc caaagcugcu auguggcagu ugcacgagcg       60

ggaggcauag aaacaauagc aaaugaauac agcgaucgau gcacccccgc auguaucuca      120

uucggaccua aaaacagauc aaucggagca gcggcaaaau cacaaguaau uucaaaugcg      180

aaaaacacug uacagggauu caaaagauuu cauggaaggg cauucaguga cccauuugua      240

gaagcugaaa agaguaacuu ggcuuaugau auagugcaac uaccaaccgg cuuaacagga      300

auaaaaguaa cauacaugga agaagaaaga aacuuuacaa cagaacaagu uaccgcaaug      360

uuacuuagua aauuaaaaga aacugcagaa agcguguuaa agaaaccagu aguagauugu      420

guugugagug uacccugcuu uuacacagau gcggaaagga gaucuguaau ggacgcuaca      480

caaauagcgg gacuaaacug cuuaagacua augaaugaaa caacagcagu cgcauuagcc      540

uacggcauuu auaaacaaga cuuacccgca uuagaagaaa aaccaagaaa cguaguuuuu      600

guggacaugg gacacucagc auaucaagua ucagugugug cauuuaauag aggcaaacua      660

aaaguauuag caacagcauu ugacaccaca cuaggaggaa ggaaauucga ugaaguacuu      720

guaaaccauu ucugugaaga guucggcaag aaauauaaac uagauauaaa aucaaaaaua      780

agagccuuau uacgacuuuc acaagaaugu gaaaaauuaa agaaacugau gucagcaaau      840

gccuccgauc ugccacuaag uauagaaugc uucaugaaug auguagaugu cucaggaacg      900

augaaccgcg guaaauuuuu agaaaugugc aaugaucuau uggcaagggu agaaccaccg      960

cuuagaagcg uccuagaaca aaccaaacua aagaaagaag auauauaugc uguagaaauu     1020

gucggaggag caacaagaau cccagcagua aaagagaaaa uaaguaaauu cuuuggaaaa     1080

gaauuaucaa caacgcuaaa ugcagacgaa gccguaacac gaggaugcgc auuacagugu     1140

gccauacuaa guccagcauu caaaguaaga gaguucagua uaaccgacgu uguaccauac     1200

ccuauaaguu uaagguggaa uagucccgca gaagaaggua gcucagauug ugaaguauuu     1260

ucuaaaaauc acgcagcacc auuuucaaaa guauuaacau ucuacagaaa agagccuuuu     1320

acacuagagg cuuauuauuc aucaccccaa gaccuaccau acccugaucc agcuauagca     1380

caauucagcg uacaaaaagu gacaccacaa agcgauggga guagcucaaa aguaaaagua     1440

aaaguaagag ucaacguaca uggaauauuu ucaguaagua gugcaagccu aguagaagua     1500

cauaaaucag aagaaaauga agaaccuaug gaaacagauc aaaacgcgaa agaagaagag     1560

aaaaugcaag uugaucaaga agaaccccau gucgaagaac aacaacaaca aacaccagcu     1620

gaaaauaaag cagaaagcga ggaaauggaa accagccaag cuggauccaa agacaagaaa     1680

auggaucaac caccccaagc aaagaaagca aaaguaaaaa cuagcacagu cgacuuacca     1740

auagaaaacc aacuccuaug gcagaucgac agggaaaugc uaaaucucua uauagaaaau     1800

gagggaaaaa ugauaaugca ggacaaacua gaaaaagaga ggaacgacgc uaaaaacgca     1860

guagaagaau acguauacga aaugagagau aaacuaucag gggaauauga aaaauuugua     1920

ucugaagaug auagaaacag uuuuacauua aaauuggaag auacugaaaa cugguuauac     1980

gaagauggcg aagaccaacc aaaacaagua uacgucgaca aacuagcuga acuaaagaau     2040

cuaggucaac caauaaaaau aagauuccaa gaaucagaag aaagaccaaa auuauucgaa     2100

gaacuaggaa aacaaauaca acaauauaug aaaauaaucu caucauuuaa aaauaaagaa     2160

gaccaauacg accaucuaga ugcagcagau augacaaaag uagaaaaauc uacuaacgaa     2220

gcaauggaau ggaugaauaa uaaauuaaac cuccaaaaua aacaaucacu gacgauggau     2280

cccguuguua aaagcaaaga aauagaggca aaaauaaaag aacuaacaag cacguguagu     2340

cccauaauau caaaaccaaa accaaaagua gaacccccaa aagaagaaca gaaaaaugcc     2400

gaacaaaaug guccaguaga uggacaagga gacaauccag gcccacaagc agcagaacaa     2460

ggaacagaua cagccgugcc aucagauagu gacaagaaau uaccagaaau ggauauugau     2520

uaa                                                                   2523


<210>  1332
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  1332
augagcguug uuggcauaga ucucggauuc cuaaacugcu auauagccgu agcuagaagc       60

gguggaauag aaacaauagc gaacgaauac ucggaccgcu gcacaccagc uuguaucagc      120

uuaggauccc gcaccagagc aauaggcaau gcagcgaaaa gccaaauagu gacaaacgua      180

cgaaauacua uacauggauu uaaaaaacua cacggaagga guuucgauga cccuauagua      240

caaacggaaa gaauacgacu cccauaugaa cuacaaaaga ugccgaaugg aagugcagga      300

guaaaaguaa gauaccucga agaagaaaga cccuuugcaa uugaacaagu aacuggaaug      360

uuacuagcaa aauuaaaaga aacaucggaa aacgcauuaa aaaaaccggu ugccgacugc      420

guaauaucca ucccaaguuu uuuuacggau gcagaaagaa gaaguguaau ggcggcagca      480

caaguagcag gauuaaauug ccuaaggcuc augaacgaaa cgacagcagu agcuuuagca      540

uacggaauuu auaaacaaga uuugccacca uuagaugaga aacccagaaa uguaguauuc      600

auagacaugg gacacucugc cuaucaagua cucguuugug cauucaauaa aggcaaauua      660

aaaguuuuag ccacaacauu cgaucccuac cucggcggaa ggaauuucga cgaagcauua      720

guagauuauu uuugcgauga auucaaaaca aaauacaaaa uaaaugugaa agaaaacucc      780

agagcauuac ucagacuaua ccaagaaugu gaaaaacuaa aaaaacuaau gagcgcaaau      840

gcaagcgacc ucccccuaaa cauagaaugc uuuaugaaug acuuggacgu aucuucaaaa      900

augaacagag cccaauucga gcaauuaugc gcgucauuac uagcccgagu agaaccucca      960

cuuaaagcag uaauggaaca agcaaacuua caacgagaag auauaucauc uauagagauu     1020

guaggaggag caacaagaau ccccgcagua aaagaacaga ucacuaaguu uuuuuuaaaa     1080

gacauuucua caacacucaa ugccgaugaa gccguugcac gaggaugugc auuacaaugc     1140

gccauauuau ccccagcauu uaagguaaga gaauucagca uuacagaccu gguuccauau     1200

ucaauaacau uaagauggaa aacaaguuuu gaagacggau caggugaaug cgaaguauuc     1260

ugcaaaaacc auccagcacc auucucuaaa guaauuacau uccauaaaaa agaaccauuu     1320

gaacuagaag cuuuuuauac uaaccuacac gaaguaccau acccagaugc aaggaucggu     1380

ucauuuacaa uacaaaacgu guucccgcaa agcgacggag acucuaguaa agugaaaguu     1440

aaaguaagag ucaauauaca uggaauauuu ucagucgccu cagccucagu gauagaaaaa     1500

cagaacuuag aaggagacca uagugacgcu ccuauggaaa cugaaacauc cuucaaaaau     1560

gaaaauaaag acaauaugga uaaaaugcaa guagaccagg aagaaggaca ucagaaaugc     1620

caugccgaac auacuccuga ggaagaaaua gaucauacag gagcaaaaac aaaaucggca     1680

guaucagaua aacaagacag auuaaaucaa acucuaaaaa aagggaaagu uaaaucaaua     1740

gacuuaccaa uacaaucgag cuuaugcaga caguuaggac aagaccuacu uaacucauau     1800

auugaaaaug aaggcaaaau gauuaugcaa gacaaauuag aaaaggagag gaacgaugcc     1860

aaaaacgcag ucgaagaaua cguauaugac uucagagaua gacuaggaac uguauaugaa     1920

aaauuuauua ccccagaaga cuuaucgaaa cuaagcgccg uucuagaaga uacagaaaac     1980

uggcuguaug aggauggaga agaucaaccc aaacaaguau acguugacaa acuacaagaa     2040

uugaaaaaau acggacaacc aauccaaaug aaauacaugg aacacgaaga aagaccaaaa     2100

gcauuaaaug aucucggaaa aaaaauccaa uuaguaauga aaguaauaga agccuaucgu     2160

aauaaagaug aaagauacga ucaucuagac ccuacagaaa uggaaaaagu agaaaaaugu     2220

auaucagaug caaugaguug guuaaauuca aaaaugaacg cacaaaauaa acuaaguuua     2280

acgcaagacc cuguaguaaa agucucugaa aucguagcaa aaagcaaaga acuggacaac     2340

uucugcaacc ccauaauaua caaacccaaa ccuaaagcag aggugccaga agacaaaccc     2400

aaagcaaauu cugaacauaa cgguccaaug gacggacaaa gcggaacaga aacaaaauca     2460

gacucaacaa aagauaguuc acaacauaca aagucaucug gcgaaaugga aguugacuaa     2520


<210>  1333
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  1333
augaaauuau cuuuaguagc ggcaaugcua uuacuacuaa gcgcagcaag ggcagaggaa       60

gaagauaaaa aagaagacgu cggaacagua gucgguauag accuaggaac cacauauuca      120

ugcgucggag uuuuuaaaaa cggaagaguu gaaaucauag caaacgauca aggaaacaga      180

aucacaccau cauacguagc guucacaccu gaaggagaac gacucauagg agaugcagca      240

aaaaaucaau uaacaucuaa cccugaaaac acagucuuug acgcaaaaag auugauagga      300

agaaccugga acgacccuuc aguucaacaa gacauaaaau uucuaccauu uaaaguagua      360

gaaaaaaaaa caaaaccaua uauacaaguu gauauuggag gcggucaaac aaaaacauuc      420

gcaccagaag aaauauccgc aaugguacuu acaaaaauga aagaaacagc ugaagcauac      480

cuaggaaaaa aaguaacaca ugccguagua acaguaccag cauauuuuaa ugacgcccaa      540

agacaagcaa caaaggaugc aggaacaaua gcuggucuaa acgucaugag aauaauaaac      600

gaaccaacag cagcagcuau cgcauacgga cuagauaaaa gagaaggaga aaaaaauaua      660

cuaguauuug aucuaggagg aggaacauuc gauguaagcu uauuaacaau agacaacgga      720

gucuuugaag uaguagcuac aaacggugac acacauuuag gaggagaaga cuuugaucaa      780

agaguuaugg aacacuuuau aaaacuauau aaaaaaaaaa ccgggaaaga cguaaggaaa      840

gauaacaggg ccguacagaa acucagaaga gaagucgaaa aagcaaaacg agcauuauca      900

ucacaacacc aagcaagaau agaaauagaa aguuucuaug aaggagaaga uuuuagcgaa      960

acucuaacgc gagcaaaauu ugaagagcug aacauggauu uauuuagaag uaccaugaaa     1020

ccaguacaaa aaguacucga agacagugau uuaaaaaaaa gugacauaga cgaaauaguc     1080

cuaguaggag guucaacccg aauccccaaa auacaacaac ucgucaaaga auuuuucaac     1140

ggaaaagaac cgagccgagg aauaaacccu gacgaagcag uagcauaugg cgcagcaguu     1200

caagcaggcg uauuaagcgg agaucaagau acaggagauu uaguacuacu agacguaugu     1260

ccacuaacuc uaggaauaga aacagucgga ggaguaauga ccaaauuaau accuagaaac     1320

acaguaguac cgacaaaaaa aucacaaauu uucuccacag caagcgacaa ucaaccaaca     1380

guaaccauaa aaguauacga aggcgaaaga ccauuaacaa aagauaacca uuuauuagga     1440

acauuugauu uaacagguau cccaccugcc ccacgaggag ucccacaaau agaaguuaca     1500

uuugaaauag auguaaaugg uauccucaga gucacagcgg aagauaaagg cacuggaaau     1560

aagaauaaaa uuacuauaac aaacgaccaa aauagauuaa cucccgaaga aauagaaaga     1620

augguaaaug augcggaaaa auucgccgaa gaggacaaaa aacuaaaaga gagaauagau     1680

accagaaacg aguuagaauc auacgcauac ucccuuaaga aucaaauugg agauaaagaa     1740

aaauuaggcg gcaaauugag cucagaagac aaagaaacca uggaaaaagc aguagaagaa     1800

aaaauagaau ggcuugaaag ccaccaggau gcagauauag aagauuucaa agcaaaaaaa     1860

aaagagcuag aggaaaucgu acaaccaaua auuucaaaac uauacggaag ugcagggcca     1920

ccaccaacag gagaagaaga caccgcagaa aaagaugaac uuuaa                     1965


<210>  1334
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  1334
augcaagcac cacgugaacu ugcagucggu auagaucuag gaacaacaua uuccugugua       60

ggaguauuuc aacaagggag aguagaaaua uuagcaaacg aucaaggcaa uagaacaaca      120

ccaucauaug uagcauuuac ugacacagaa agauugguag gagaugcagc caaaagucaa      180

gcagcauuaa auccacauaa cacaguguuc gacgcgaaaa gacuaauugg uagaaaauuu      240

gcggauacaa caguccaaag ugacaugaag cauuggccau uuaggguagu gucugaaggu      300

ggaaaaccaa aaguaagagu augcuauaga ggugaagaua aaacauuuua uccagaagaa      360

auuucaucaa ugguauuaag caaaaugaaa gagacagcag aagcauaccu uggacaacca      420

guaaaacaug cuguaauaac aguucccgca uacuucaaug auagccaaag acaagcaaca      480

aaagaugcug gagcaauagc uggauuaaac gugcuaagaa uuauaaauga accaaccgcc      540

gcggcaauug cauauggauu agauagaaga ggagcaggag aaagaaacgu auuaauauuc      600

gaucuaggag gaggaacauu ugacguauca gucuuaucaa uagacgcagg cguauucgaa      660

guaaaagcaa cagcugguga uacucacuua ggaggagaag auuucgauaa cagauuaguu      720

aaucacuuca uggaagaauu ucgacgaaaa cauggcaaag aucuauccgg caauaaaaga      780

gcauuaagaa gacuacgaac agcgugugaa agagcaaaaa gaacauuauc cucaucuacc      840

caagcuacau uagaaauaga uagccuauuc gaagggguag auuuuuacac uuccauaaca      900

agagcucgcu ucgaggaacu augcucagau uuauuuagau cuacuuuaga accuguagaa      960

aaagccuuac gugacgcaaa auuagauaaa gcacaaauac augacgucgu auuaguaggu     1020

ggaaguaccc gaauaccaaa aguacaaaaa cuauuacaag auuucuuuaa cggaaaagaa     1080

cuaaacaaau caauuaaucc agaugaagca guugcuuacg gcgcagcagu acaggcagca     1140

guauuaaugg gagauaaaug ugaaaaagua caagauuugu uacuucuaga cguggcaccc     1200

cuaagccuag gauuagaaac agcaggagga guaaugacca cauuaauaca aagaaaugca     1260

acaauaccua cuaaacaaac acaaacauuu acaacauaua gugacaauca accuggggua     1320

uucauacaag uauaugaagg ugaaagagca augacaaaag auaauaauuu acuagguaga     1380

uuugaauuau cagggauucc accagcacca cgaggaguac cgcaaauaga ggugacuuuu     1440

gacauagacg caaauggcau cuuaagcgua acagcaacag auagaagcac aggaaaagca     1500

aacaaaauaa caauaacaaa ugacaaagga agguuaagca aagaggaggu cgaaaggaug     1560

guacaugaag cagagcaaua uaaggccgaa gaugaagccc aaagagacag aguagcagcu     1620

aaaaauucac uagaagcaca uguguuucac guaaaaggga gcuuacaaga agagaguuua     1680

agagauaaaa uaccagaaga agauagacga aaaaugcaag auaaaugcag agaaguauua     1740

gcauggcuag aacauaauca acuggcagaa aaagaagaau augaacauca aaaacgagaa     1800

uuagaacaaa uaugcagacc aauauucuca aggcuauaug gcggaccagg aguaccagga     1860

ggaaguucuu guggaacuca agcuagacaa ggagacccuu cuacaggacc aauaauugaa     1920

gaaguagauu aa                                                         1932


<210>  1335
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__P48741__HsHSPA7

<400>  1335
augcaagcac ccagagaauu agccguagga auagaccuag gaacuacaua uagcuguguc       60

ggaguauuuc aacaaggaag aguugaaaua uuagcaaaug accaaggaaa uagaacaaca      120

ccuucauaug uagcauucac agacacagaa agguuaguag gagaugccgc gaaaagccaa      180

gcagcauuaa acccacacaa uacaguauuc gaugcaaaaa gacucaucgg aagaaaauuu      240

gcagauacaa caguacaauc agauaugaaa cauuggccau uucaaguagu cucagaaggc      300

ggaaaaccaa aaguaagagu auguuacaga ggagaagaua aaacauuuua uccagaagaa      360

auaucaagua ugguauuauc aaagaugaaa gaaacagcag aagcauaucu aggccaacca      420

guaaaacaug caguaauaac aguaccaacu uauuucucaa auucacaaag acaagcaaca      480

aaagaugcug gagcaauugc aggucuaaaa guauuaccaa ucauaaauga agcuacagcu      540

gcagcaauag cauauggccu agauagaaga ggagcaggaa aaagaaaugu auuaauauuu      600

gauuuaggag gaggaaccuu ugacguauca guauuaucaa uagaugcagg aguauuugaa      660

guaaaagcaa cagccggaga uacacaucua ggaggagaag auuucgacaa cagauuaguu      720

aaucacuuca uggaagaauu uagaagaaaa cacggaaaag acuuaucagg uaauaaaaga      780

gcacuuagaa gauuaagaac agcaugugaa agagccaaaa gaacaccauc aagcucaaca      840

caagcgacau uagaaaucga uucacuauuc gaaggaguag auuuuuauaa aucaauaacu      900

agagcccgau uugaagaauu auguucagac uuauuucgaa gcacacuaga accaguagaa      960

aaagcacuaa gagaugcaaa acuagacaaa gcacaaauac acgacuucgu auuaggagga     1020

ggacuacaca gucauccaca aggagcugaa guagcugcag gauuauuaca aagacaagga     1080

gcagaacaag aacaccaacc uuaa                                            1104


<210>  1336
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  1336
augucaaaag guccugcugu aggaauugac uuaggaacga cauauucgug uguugguguc       60

uuccaacaug ggaaaguaga aauuauagca aacgaucaag gaaaccgaac aacaccauca      120

uacguagcuu uuacagauac agaaagauua aucggagacg cggcuaaaaa ucaaguagca      180

augaauccaa caaacacagu cuuugacgca aaacgacuaa uaggaagaag auuugaugau      240

gcaguaguuc aaagcgauau gaaacacugg ccauuuaugg uaguaaauga cgcaggaagg      300

ccaaaaguac aaguagaaua caaaggagaa acaaagagcu ucuauccgga agaaguauca      360

agcaugguau uaacaaaaau gaaagagaua gcagaggcau acuuaggaaa aacaguaaca      420

aacgcaguag ucacaguucc agcauauuuc aacgauagcc aaagacaagc aacaaaagac      480

gcagguacaa uagcaggauu aaauguacuc cggauaauaa acgaaccaac agcugcugca      540

aucgcguaug gacuagauaa gaaaguaggc gcagaaagaa auguauuaau cuucgacuua      600

ggaggaggaa cauucgaugu aucuauucua acaauagaag acggcauauu cgaaguaaaa      660

agcacagccg gcgacacaca cuuaggagga gaagauuucg auaaccgaau gguaaaccau      720

uucauagccg aguucaaaag gaaacacaag aaagacauaa gugaaaauaa aagagcagua      780

cgccgauuaa gaaccgcaug ugaaagagca aaaagaacuc uaaguucaag cacacaagcg      840

aguauagaaa uagacaguuu auaugaaggu auagauuuuu auacaucaau aacaagagca      900

agauucgaag aacuuaacgc agaccuauuu agaggaacac uagacccagu agaaaaagca      960

cuaagagaug caaaauuaga caaaagccaa auacaugaua uaguauuggu cggaggaucg     1020

acuagaaucc caaaaauaca aaaacuauua caagacuucu uuaacggaaa agaacucaau     1080

aaaucgauua auccagauga agcagucgca uauggagcug cgguacaagc cgcgauauua     1140

agcggagaca aauccgaaaa cguccaagau cuauuacucu uagacguaac accucugucg     1200

cuaggaauug aaacagccgg ugggguaaug acaguacuaa uaaaaagaaa caccacaaua     1260

ccaacuaaac aaacacaaac auuuacuaca uacucagaua aucaaccagg aguccuaauu     1320

caaguuuacg aaggggaacg ugcaaugaca aaagacaaua auuuacucgg aaaauuugaa     1380

cuaacaggaa uaccaccagc accaagagga guaccacaaa uagaaguaac auuugauaua     1440

gaugcaaaug gaauacuaaa cguaagugcg guagauaaaa gcacagguaa agaaaacaaa     1500

auaacaauaa cuaacgacaa aggcagauua ucaaaagaag auauagaaag aauggugcaa     1560

gaagcagaaa aauauaaagc agaagacgaa aaacaaagag auaaaguaag uaguaaaaau     1620

ucauuagaau cauacgcauu uaauaugaaa gcaacgguag aagaugaaaa auugcaagga     1680

aaaauaaacg augaagauaa gcagaaaauu uuagacaaau guaacgaaau uauaaauugg     1740

uuagauaaaa aucaaacagc agagaaagag gaauuugaac aucaacaaaa agaauuggaa     1800

aaggucugca auccuauaau aaccaaauua uaccaaucug cgggaggaau gccaggcgga     1860

augccaggag gauucccagg uggaggagcu ccaccaagcg gaggagcaag caguggacca     1920

acaauagaag aagucgauua a                                               1941


<210>  1337
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  1337
augaucagug caagcagagc ugccgcagca agauuaguag gagcggcagc aagcagagga       60

ccaaccgcug cuagacauca agauaguugg aauggauuau cacacgaagc auuuagacuc      120

guaaguagac gagacuaugc aagcgaggca auaaaaggcg caguaguagg gaucgauuua      180

gggacgacaa acucaugcgu agcagucaug gaaggaaaac aagcaaaagu acuagaaaau      240

gcagaaggag cgagaacaac accaucagua guagcguuua cugcagaugg agaaaggcua      300

guaggcaugc ccgcuaaaag acaagcagua acaaauccaa auaauacauu uuaugcaaca      360

aaaagauuaa uaggaagaag auaugaugac ccagagguac agaaagacau caaaaaugua      420

ccuuuuaaaa uaguaagagc aaguaacgga gacgcauggg uagaagcaca ugguaaacua      480

uauaguccgu cgcaaauagg agcauuuguu cuuaugaaaa ugaaagaaac ggcagaaaau      540

uaucuagggc auacagccaa gaacgcagua auaacaguac ccgcauauuu caacgauuca      600

cagcgucaag caacgaaaga ugcgggacaa auuagugggc ugaauguauu aagaguaaua      660

aacgaaccca cagcugcagc ccuagcguau ggacucgaua aaucagaaga caaaguaauc      720

gcaguauaug auuuaggugg gggaaccuuu gacauuucaa uauuagaaau acaaaaaggc      780

guauuugaag uaaaaaguac aaauggagau acauucuuag gaggagaaga cuucgaucaa      840

gcucuauuac gacauauagu gaaagaguuc aaaagagaaa caggaguuga cuuaacaaaa      900

gauaacaugg cacuacaaag aguaagagaa gcagcugaaa aagcgaaaug cgaacuaagu      960

aguaguguac aaacagacau aaacuuacca uacuuaacaa uggacucauc agggccaaaa     1020

caucuuaaca ugaaacugac uagagcacaa uucgaaggaa uagucaccga ucuaauacgu     1080

aggaccauug caccaugcca gaaagcaaug caggacgcag aaguaucgaa aagcgauaua     1140

ggagaaguaa uauuaguugg gggaaugaca agaaugccua aaguacaaca aacaguacaa     1200

gauuuauuug gaagggcacc aucaaaagca guaaacccag acgaagcagu ggcgauagga     1260

gccgcaauac aaggaggagu acuagcagga gacguaacug auguuuuauu acuagaugua     1320

accccacuaa guuugggaau agaaacauua ggaggaguau uuacaaaacu aauaaauaga     1380

aauaccacaa uaccuacaaa gaaaucucaa guauuuucaa cagcagcaga cggccaaaca     1440

caaguggaaa uaaaaguaug ucaaggcgaa agagaaaugg caggagacaa uaaacuguua     1500

ggacaauuua cuuuaauagg uauaccacca gcaccaaggg gaguaccuca aauugaagua     1560

acauucgaca uagacgcaaa uggaauaguc cauguaucag cgaaagauaa gggcacaggg     1620

agggaacaac aaauaguaau acaaaguagc ggaggacuga guaaagacga uauagaaaau     1680

auggucaaaa augcugaaaa auaugcugaa gaggauagga ggaagaaaga aaggguagaa     1740

gcgguaaaua uggcagaagg aauaauacau gacacagaaa caaaaaugga agaauuuaaa     1800

gaucaauuac cagcggauga auguaauaaa cucaaagaag aaauaaguaa aaugagagag     1860

uuacuugcaa gaaaagauuc agaaacggga gaaaauauac gacaagcagc aaguucacua     1920

caacaagcua gucuaaaauu auucgaaaug gccuauaaga aaauggcauc ggaacgagaa     1980

ggaucaggau caucugguac aggggaacaa aaagaagauc aaaaagaaga aaaacaauaa     2040


<210>  1338
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  1338
auggcugaua aagaagccgg aggaucugau ggcccuagag aaaccgcacc aacuucagca       60

uauagcagcc ccgccagauc auuaggagau acaggcauaa cucccuuauc accaucccau      120

auaguaaacg auacagauag uaaugucucc gaacaacaau cauuuuuggu uguuguagca      180

gucgauuucg guacaacaag cuccggauac gcauauuccu ucacaaaaga accggaaugu      240

auacauguua ugagaagaug ggaaggcggc gacccaggag uuaguaacca aaagacucca      300

acuacaaucc ucuuaacacc ggaaaggaaa uuccauucau ucggauaugc cgcacgcgau      360

uuuuaccacg auuuagaccc aaacgaagcg aaacaauggu uauaucuaga aaaauuuaaa      420

augaaacuac auaccacagg agaccuuacu auggauacag accuaacagc ugcaaaugga      480

aagaaaguaa aagcauuaga aaucuuugca uacgcguuac aauacuuuaa agaacaagcc      540

uuaaaagaau uaagcgacca agcuggauca gaauuugaaa auuccgacgu acgauggguc      600

auaacgguac cugcaauaug gaaacaacca gcaaaacaau ucaugagaca agccgccuau      660

caagcuggac uagcgucacc agaaaacagc gaacaacuaa uaauagcacu agaaccagaa      720

gcagcaucaa ucuauuguag aaaacuaaga uuacaucaaa ugauagaacu aucaucaaaa      780

gcugcaguaa auggauauuc aggaagugac accguaggug caggauuuac ucaagccaaa      840

gaacacauaa gaagaaauag acaaucuaga accuuucuag ucgaaaaugu aauuggcgaa      900

auauggucug aauuagaaga aggagacaaa uaugucguag uugacuccgg uggaggaaca      960

guggaucuca ccguccauca aauacgacua ccagaaggac aucuuaaaga acucuacaaa     1020

gcuacaggag gaccauaugg cucauuaggc guagauuaug aauuugaaaa acugcuauac     1080

aaaaucuucg gagaagacuu uauagaacaa uuuaaaauca aaagaccagc agcaugggua     1140

gauuuaauga uagcauucga aucaagaaaa agagcugcag caccagaucg aacuaauccg     1200

uuaaauauaa cguuaccauu cucauucauu gacuacuaua aaaaguuuag aggucauagu     1260

guugaacaug cacuaagaaa aucgaaugua gauuuuguaa aauggucaag ucaaggcaug     1320

uuaagaaugu caccagaugc caugaaugca uuauuuaaac caacuauaga uucaauaaua     1380

gaacauuuaa gagacuuauu ccaaaaacca gaaguaucua caguuaaauu cuuauuccua     1440

guagggggau uugcagaagc uccacuucua caacaagcag ugcaagcagc auucggcgac     1500

caaugucgaa uaauaauacc ucaagacgua ggccucacaa uacuaaaagg agcgguauua     1560

uuuggauuag auccugcagu cauaaaagua agaagaucac cucuaacaua cgguguagga     1620

guacuaaaca gguacguaga aggaaaacac ccaccugaaa aacuuuuagu caaagacgga     1680

acuagauggu gcacagaugu auuugauaaa uucauaucag cagaucaauc aguagcauua     1740

ggagaacugg uaaaacgauc auacacuccu gcuaaaccca gccaauuagu aaucguaaua     1800

aauauauauu caagugaaca ugauaauguc ucauuuauaa cagauccagg aguaaagaaa     1860

ugcggaacau ugagauugga ccucacagga acaucaggaa cagcuguacc agcaagacga     1920

gaaauucaaa cacuaaugca auuuggagau accgaaauaa aagcaacugc aauagauaua     1980

gccaccagca aaaguguaaa agugggaauc gauuucuuaa auuauuaa                  2028


<210>  1339
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  1339
augcuagcag uaccugaaau gggauuacaa ggucuauaua uagguagcuc gccagaacga       60

ucaccaguac caaguccgcc gggaucaccu cgcacacaag aaagcugugg aauugcacca      120

cuaaccccuu cucaaucacc aaagccagaa guuagagcac cccaacaggc uucauuuucu      180

guaguaguag caauagacuu uggcaccaca uccucaggcu augccuucag cuuugcauca      240

gacccagaag cgauacauau gaugaggaaa ugggaaggag gagauccagg gguagcacau      300

cagaaaacac cuacuugcuu auuacuaaca ccagaaggcg cauuucauag uuuuggauau      360

acagcaagag acuauuauca ugaucuggau ccugaagaag cgcgugauug guuauauuuu      420

gaaaaauuua aaaugaaaau ccauucagca acagaucuaa cuuuaaaaac acaauuagaa      480

gcugucaaug gcaaaacaau gccagcauua gaaguauuug cccaugcacu aagauuuuuc      540

cgagaacaug cacuacaaga acuuagagaa caauccccaa guuuaccuga gaaagauaca      600

guaagauggg uauuaacagu gccggcaaua uggaaacaac cugcuaaaca auucaugagg      660

gaagccgccu auuuagcagg auugguuuca cgagaaaacg cagaacaacu auugauagcu      720

uuagagccag aggcggcaag uguauauugu agaaaacuaa gauuacauca acuacuagau      780

uuaucaggca gagcuccagg aggagguaga uuaggagaaa gacgauccau ugauucuagu      840

uuuagacaag cuagagaaca acuaagaaga agcagacauu caagaacauu ccuuguagaa      900

aguggaguag gagaauuaug ggcagaaaug caagcaggag auagauaugu aguugcagac      960

uguggaggag gaacuguaga ccucacaguu caucaacuag aacaaccaca ugguacccua     1020

aaagaauuau auaaagcgag uggcggccca uacggagcag uaggcguaga uuuagcauuu     1080

gaacaauuac ucugucgaau auuuggagaa gauuucauag cuacuuuuaa aagacaaaga     1140

ccagcugcau ggguagaucu aacuauagcu uucgaagcaa gaaaaagaac agccggaccu     1200

cauagagcag gagcauuaaa uauaucucua ccauuuaguu uuauagauuu uuacagaaaa     1260

caacggggac auaacguaga aacggcauua cgaagaucaa gugucaacuu cguaaaaugg     1320

ucaucacaag guauguuaag aauguccugu gaagcaauga augaacuauu ucaacccacu     1380

guaagcggaa uaauacaaca cauagaagca uuauuagcaa gacccgaagu ucaaggagua     1440

aaauuacuau uucuaguagg aggguuugcc gaaucggcag uucuacaaca ugcaguacaa     1500

gcugcguuag gcgcacgagg auuacgagua guaguacccc acgauguugg gcuuacaauu     1560

cugaaaggag cuguauuauu uggacaggca ccaggaguag ucagaguuag aagaagccca     1620

cuaacauaug ggguaggagu acuuaacaga uuuguaccag gcaggcaucc uccagaaaaa     1680

uuauuaguac gagacggaag acguuggugu acagauguau ucgaaagauu cguugcagcu     1740

gaacaaagcg uugcauuagg agaagaagua agacgaucau auugcccagc uagaccaggu     1800

caaagaagag uucuaauaaa cuuauauugu ugcgccgcag aagaugcaag guuuauuacu     1860

gauccuggag uucgaaaaug uggugcacuu agccuagaac uagaaccggc cgauugugga     1920

caagauacag ccggagcacc accagguaga agagaaauaa gagcugcuau gcaauucgga     1980

gacaccgaaa uaaaagucac agcaguagau gucagcacaa auagaucagu gcgagcuagu     2040

auagacuuuc uaucaaauug a                                               2061


<210>  1340
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  1340
auggcacgag aaaugaccau auuaggaagc gccguauuaa cauuauuacu agcgggauau       60

uuagcacaac aauaucuacc ccuacccaca ccaaaaguaa ucggaauaga cuuaggaaca      120

acauauugua guguaggagu uuucuuccca ggaaccggaa aagucaaagu aauaccagac      180

gaaaacggac acauaucaau uccaucaaug guaucauuua cugauaacga cguauaugua      240

ggauacgaau caguagaauu agccgauagc aauccacaaa acacuauaua ugacgcaaaa      300

agauucauag gcaaaauauu uacagcagaa gaacuugaag cugaaauagg aagauauccc      360

uuuaaaguac uaaauaaaaa cggaauggua gaauucucag uuacaucaaa ugaaacaaua      420

acagucaguc cagaauacgu agguagcaga uuacuacuaa aacuaaaaga aauggcagaa      480

gcauacuuag gaaugccagu agcaaaugcc guaauaucug uaccagcaga auucgauuua      540

aaacaacgaa auucaacaau agaagcagcu aaucuagcag gacuaaaaau auuaagaguu      600

auaaacgaac ccacagcagc agcaauggcc uauggauuac acaaagcuga cguauuucau      660

guacuaguaa uagaucuagg uggagguaca uuagacguaa gcuuacuaaa uaaacaagga      720

ggcauguuuc uuacacgagc aaugucaggc aacaacaaau uaggagguca agacuuuaac      780

caaagacuac uacaauaucu cuacaaacaa auuuaccaaa cuuauggauu uguuccuuca      840

agaaaagaag aaauacaucg auuacgacaa gcaguagaga ugguaaaacu aaauuuaaca      900

cuacaucaga gugcacaacu uuccgucuua uuaacaguug aagaacaaga ucgaaaagaa      960

ccacacaguu cagacaccga acuuccaaaa gauaaauuaa gcucagcaga ugaccauaga     1020

guuaacagcg gcuuuggaag aggauuauca gacaaaaaaa gcggagaaag ccaagugcug     1080

uuugaaaccg aaauaagcag aaaauuauuc gauacacuua acgaagaccu auuccaaaaa     1140

auauuaguac caauccaaca aguacuaaaa gaaggucauc uagaaaaaac agaaauagau     1200

gagguaguau uaguaggagg aucaacacgu auacccagaa uaagacaagu aauacaggaa     1260

uuuuucggaa aagauccaaa uacaucagua gacccagauu uagcgguugu uacaggaguc     1320

gcaauacaag caggaauaga uggcggaagc uggccauuac aaguauccgc acuagagauc     1380

ccaaacaaac aucuacaaaa aaccaauuuc aauuaa                               1416


<210>  1341
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  1341
auggcagcaa uaggaguaca uuuaggaugu acaagugcau guguagcagu auauaaagau       60

ggaagagcag gaguaguagc caaugaugca ggggauagag uaacaccagc gguaguagcu      120

uauucagaaa augaagaaau aguaggauua gcugcaaaac aaucaagaau aagaaauauu      180

aguaacaccg uaaugaaagu gaaacaaaua cuaggaagau cuucaucaga uccccaagca      240

caaaaauaua uagcagaauc aaaaugucua guaauagaaa aaaauggcaa acuaagauau      300

gaaauagaua caggcgaaga aacaaaauuu guaaacccug aagaugucgc uagacuaaua      360

uucucaaaaa ugaaagaaac agcacauuca guacuaggau cagaugcaaa ugacguagua      420

auaaccguac cauuugauuu uggagaaaaa caaaaaaaug cauuaggaga agcagcaaga      480

gcagcaggau uuaacguguu acgacuuaua caugaacccu cagcagcauu auuagccuau      540

ggaauagguc aagacucacc aacaggcaaa ucaaauauau uaguauuuaa auuaggagga      600

acuagucuau cacucucagu aauggaagua aauucaggaa uauacagagu uuuaucaacu      660

aauacagaug auaauauugg aggagcacau uuuacagaaa cauuagcuca auaccuugca      720

agugaauuuc aaagaaguuu uaaacacgau gucagaggaa augcaagagc aaugaugaaa      780

cuaacgaauu cagcagaagu agcaaaacau ucauuaucaa cauuaggguc ugccaauugu      840

uuccuagaua gucuuuauga agggcaagac uuugacugua auguaagucg agcaagauuu      900

gaacuacugu guucaccccu guuuaacaag ugcauagaag caauaagggg auuacuagau      960

caaaauggcu ucaccgcaga ugacaucaau aaaguaguac uauguggagg aagcucaaga     1020

auaccaaaac uccaacaauu aauaaaagau uuauuucccg cuguagaacu acuaaauagu     1080

auacccccag augaaguaau accaauaggu gccgcaauag aagcaggcau auuaauaggc     1140

aaagagaauc uacuagugga agacagucua augauagaau guagugcaag agacauauua     1200

guaaaagggg uagaugaaag uggagcaagc agauuuacag uauuauuccc cagcggaaca     1260

ccucuaccag caagaagaca acauacucua caagcgccag guucaauauc aucaguuugc     1320

cuagaacuau acgaaucaga cgguaaaaac ucagcaaaag aagaaacaaa auucgcucaa     1380

guaguacuac aagauuugga caaaaaagag aauggacuaa gagauauucu agccguauug     1440

acuaugaaaa gagauggauc acuacacgua acauguacag accaagaaac aggaaaaugu     1500

gaagcaaucu cuauagaaau agccucauaa                                      1530


<210>  1342
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  1342
augaguguug uggggcuaga cguagggagc caaaguugcu auauagcagu agccagagcc       60

ggaggaauag aaacgauagc aaaugaauuc ucagauagau gcaccccaag uguaauauca      120

uucggaucaa aaaacaggac gauaggagug gcagccaaaa aucaacagau aacgcacgca      180

aauaacacag ucagcaacuu uaaaagauuu cacggaagag cauuuaacga cccauuuaua      240

caaaaagaaa aagagaaucu aaguuacgac uuaguccccc uaaaaaaugg aggaguggga      300

auaaaaguaa uguauauggg cgaagaacac cuuuuuucag uugaacaaau aacugcgaug      360

cuauuaacaa aacuaaaaga aacagcagaa aacucauuaa aaaaaccagu aacagacugc      420

guaauaucag uaccaucauu cuuuacagac gcugaacgac gaaguguucu agacgcagca      480

cagauaguag guuugaauug ucuaagacug augaacgaca ugacagcagu agcguuaaac      540

uacggaauau acaaacagga ccuaccaagc uuggacgaga aaccuagaau aguaguauuc      600

guagacaugg ggcacucugc auuccaaguu agugcaugcg cauucaauaa agguaaacuc      660

aaaguauuag gaacagcauu ugacccauuc uuaggaggca aaaacuuuga cgaaaaacuu      720

guugaacauu ucugcgcgga auucaaaaca aaauauaaau uggacgccaa aagcaaaaua      780

agagcccuuu uacgacuaua ccaagagugc gaaaaacuaa aaaaacuaau gaguaguaau      840

ucaacugacc uaccacucaa uauugagugu uucaugaaug auaaagaugu aaguggcaaa      900

augaacagau cucaauucga agaauuaugc gccgaauugc uacagaaaau agagguacca      960

cuauauagcc uccuagaaca aacacaucua aaaguagaag auguuagugc aguggaaaua     1020

guaggaggcg cuacaagaau accugcaguu aaagaaagaa ucgcuaaauu cuucggaaaa     1080

gauauaucca caacacuuaa ugcagacgaa gcaguagcuc gcggcugcgc ucuccaaugu     1140

gccauucuaa guccagccuu caaagucaga gaauucucug uaacugacgc aguuccguuc     1200

ccuauaucac uuauauggaa ccacgacagu gaagauacug aaggagugca ugaaguauuc     1260

agcaggaacc augccgcucc uuucagcaaa guauuaacuu ucuuacgaag gggaccauuc     1320

gaauuagaag cauuuuacuc agauccacaa ggaguaccau acccugaagc aaaaauaggc     1380

cgauucguag uacaaaacgu cagcgcacaa aaagauggag aaaaaucaag agucaaagua     1440

aagguacgug uaaauaccca cgguauuuuc acaauaucaa cagcauccau gguagaaaaa     1500

guaccuacag aagaaaauga aaugucaagc gaagcagaua uggaaugcuu aaaucaaaga     1560

ccaccagaaa acccagauac agacaaaaac guacaacaag auaacucaga agcaggaaca     1620

caaccacaag uacaaaccga ugcucaacaa accucacaau caccuccaag cccagaacuu     1680

acuucugaag aaaacaaaau cccagacgca gauaaagcca acgaaaaaaa agucgaccaa     1740

ccaccagaag cuaaaaaacc aaaaauaaaa guaguaaacg uagaacugcc cauagaagca     1800

aaccuaguau ggcaacuagg aaaagauuua uuaaacaugu acauagaaac ugaaggcaaa     1860

augaucaugc aagauaaacu agaaaaagaa cgcaaugacg caaaaaacgc aguagaagaa     1920

uauguauaug aauuuagaga caaauuaugu ggaccauaug aaaaauucau augcgaacaa     1980

gaucaccaaa auuuccuacg acuacucacu gaaacagaag acugguuaua ugaagaagga     2040

gaagaccaag caaaacaagc uuacguagac aaacuggaag aacuaaugaa aauagguacg     2100

ccuguaaaag uacguuucca agaagcagaa gaaagaccga aaauguuuga agaauuagga     2160

cagagacucc aacacuaugc aaaaauagcu gcagacuucc gaaacaaaga ugaaaaauau     2220

aaccacauag augaaagcga aaugaaaaaa guugaaaaau cagucaacga aguaauggaa     2280

uggaugaaca acguaaugaa ugcacaagca aaaaaaaguc uagaccaaga cccaguaguc     2340

agggcgcaag agauaaaaac gaaaaucaaa gaauuaaaua acacuugcga acccgucgua     2400

acgcaaccaa aaccuaaaau agaaucacca aaacuagagc gcacgccuaa ugguccaaac     2460

auagacaaaa aagaagagga ccuagaagau aaaaauaacu uuggugcaga acccccccau     2520

caaaacggag aaugcuaucc aaacgaaaaa aauaguguaa auauggaucu agacuaa        2577


<210>  1343
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  1343
auggcugaua aaguaagaag acaaagaccc agaaggagag uuuguugggc ucuaguagca       60

guauuacugg cagauuuauu agccuuauca gauacccuug caguaauguc cguagaccua      120

ggaagugaaa guaugaaagu agcaauaguu aaacccggag uaccaaugga aauaguccuu      180

aacaaagaau cuagaaggaa aacuccaguu auaguaacac uaaaagaaaa ugaacgauuc      240

uucggcgaca gugcagcauc aauggccauc aaaaauccaa aagcaacauu aagauacuuu      300

caacaucuuc uuggcaaaca agcugauaau ccucaugucg cauuauauca agcaagauuc      360

cccgaacacg aacuaacuuu ugacccacaa cgucaaacug uacacuuuca aauaaguuca      420

caacuacaau uuaguccaga agaaguacuc ggaauggucc ugaauuauuc aagaucauua      480

gcagaagauu ucgcagaaca accuauaaaa gacgcaguaa uaaccguucc uguguucuuu      540

aaccaagccg aaaggcgagc aguauuacaa gcagcucgaa uggcaggauu aaaagucuua      600

caauugauaa augauaauac agcaacagca cuuaguuacg ggguauuuag acgaaaagau      660

aucaauacga cagcucaaaa uauaauguuu uaugacaugg gaaguggcuc aacagucugc      720

acaauaguaa cauaucaaau ggucaaaaca aaagaagccg ggaugcaacc acaacugcaa      780

auacgaggug uaggauucga uagaaccuua gggggacuag aaauggaauu aagauuacga      840

gaaagauuag caggauuauu uaacgaacaa aggaaaggcc aacgugcaaa ggauguaaga      900

gaaaauccaa gagcgauggc aaaacuccug agagaggcua auaggcuaaa aacggugcua      960

agcgcaaaug cggaccauau ggcacaaaua gaaggguuaa uggaugacgu agacuuuaaa     1020

gccaaaguaa cacgcguaga guucgaagaa uuaugugcug aucuauuuga aagaguaccg     1080

gguccaguuc aacaagcguu acaaucggca gaaaugucac uugaugaaau agaacaagua     1140

auuuuaguag ggggcgcuac caggguuccu aggguacaag aaguccuauu gaaagccgug     1200

gggaaagaag aauuagguaa gaauauaaac gcagaugaag cugcugcaau gggugcagug     1260

uaucaagcag cagcacuaag caaggcauuu aaggugaaac cguucguugu aagggaugcu     1320

guagucuauc caauauuagu agaauuuacu cgcgaaguag aagaagaacc aggaauacau     1380

uccuuaaaac auaauaaaag agucuuauuc agcaggaugg gacccuaucc ucagagaaaa     1440

guaauaaccu ucaaccgaua cagucaugac uucaauuucc acauaaacua uggagauuua     1500

ggauuucuug guccggaaga cuuaagagua uuuggaaguc aaaaucuaac aaccguaaaa     1560

uuaaaaggcg ugggagacuc auuuaagaag uaucccgauu acgaaucaaa aggaauuaag     1620

gcacauuuua acuuagacga gagcggaguc uuaagccugg acagagugga aucaguauuc     1680

gaaacguugg uugaagauuc agcugaagaa gaaaguacac uaacgaaauu gggaaacacc     1740

auaaguucuc uauucggagg aggcacaacu ccagaugcaa aagaaaaugg uacagauacu     1800

guccaagaag aagaagaauc accagcagaa ggauccaagg acgaaccagg agagcaaguu     1860

gaacuuaaag aagaagcaga agcacccguu gaagauggau cacaaccucc accacccgaa     1920

ccgaaaggag acgccacgcc ggaaggagaa aaagcaacug aaaaagaaaa uggagauaaa     1980

ucagaagcac aaaaaccauc ugaaaaagcc gaggcaggac cagaaggugu agcucccgcu     2040

ccggaaggug aaaagaaaca aaaaccagca cgaaaaagac gcauggucga agaaauagga     2100

guagaauuag uaguuuuaga cuuaccugau cucccagaag acaaacucgc acaaucagua     2160

caaaaacuac aagaucuaac auugagagau cuggagaaac aagaaagaga aaaagcagcu     2220

aauagucuag aggcuuucau uuucgaaacc caagacaaau uauaccaacc ugaauaccag     2280

gaaguuucca cagaagaaca aagggaagaa aucaguggua aauugagcgc agcuaguaca     2340

ugguuagaag augaaggagu uggagcaacg acaguaaugu uaaaagaaaa auuagcagaa     2400

uuaaggaaau uaugucaagg acucuucuuu agagucgaag aaagaaagaa auggcccgag     2460

agauugucag cauuagacaa uuuauuaaac cauuccagca uguucuuaaa aggugccaga     2520

cuuauaccag aaauggauca gauauuuaca gaaguggaaa ugacuacacu agaaaaagua     2580

auuaacgaaa ccugggcaug gaaaaaugca acacuagcag aacaagccaa auuaccggcg     2640

acggagaaac caguacuauu aucgaaagau auagaagcaa aaaugauggc ucuagaccga     2700

gaaguccaau accuuuuaaa caaagccaaa uuuacaaaac caaggccaag accuaaagac     2760

aaaaauggaa caagagcgga accaccacua aacgcgagcg caagugacca aggugaaaaa     2820

guaauuccac cagcuggaca aacagaagac gcugaaccca uaagugaacc agaaaaagua     2880

gaaacaggau cagaacccgg agauacugaa ccacuagagu ugggaggacc aggggcugag     2940

cccgaacaaa aagaacaauc aacaggccag aaaagaccgc ucaaaaacga ugaacuauaa     3000


<210>  1344
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  1344
augccagaag aaacgcaaac acaggaccaa ccaauggaag aagaagaagu ugaaacauuu       60

gccuuccaag cugaaaucgc ucaacuaaug ucccucauaa uaaacacauu uuacaguaau      120

aaggaaauau uccuacgaga auuaauauca aauaguagug acgcauuaga uaaaauacgu      180

uacgaaagcc uaacagaucc gaguaaacua gacucaggaa aagaacuaca cauaaacuua      240

auaccaaaca aacaagaccg aacacucaca auaguagaca cagguauagg caugacgaaa      300

gccgauuuaa uaaacaaccu cggaaccauu gcaaaaagcg gaaccaaggc auucauggaa      360

gcucuacaag caggagcgga caucagcaug auaggccagu ucggaguggg uuucuauuca      420

gcauaccucg uagcagaaaa aguaaccguc auaacgaagc acaacgacga ugaacaauau      480

gcaugggaau cauccgccgg aggaaguuuc acaguccgaa cugacacagg ugaacccaug      540

ggaagaggua cuaaaguaau ccuucaucug aaagaagauc aaaccgaaua ccucgaagaa      600

cgacgaauaa aagaaauugu aaaaaagcau ucacaauuca ucggauaccc uauaacacuc      660

uucguagaaa aagaaaggga uaaagaagua agcgaugaug aagcagaaga aaaggaagac      720

aaagaagaag aaaaagaaaa agaagaaaaa gaaucagaag auaaaccaga aauagaagac      780

guaggauccg acgaagaaga agaaaaaaaa gacggugaca aaaaaaaaaa aaaaaagaua      840

aaagaaaaau acauagacca agaagaauua aauaaaacca aaccgauaug gacgagaaau      900

cccgacgaca uaaccaacga agaauacgga gaauucuaua aaagccugac caacgacugg      960

gaagaccauc uggcagucaa acacuucagu guagaaggac aauuagaauu cagagcacua     1020

cuauuuguac cgagacgagc accauucgac uuauucgaaa auagaaaaaa aaaaaacaac     1080

auaaaauugu acguaagaag ggucuucaua auggacaauu gugaagaacu aauacccgaa     1140

uaucuaaacu ucauuagagg cguuguagac ucagaagacc uuccacucaa uauaucaaga     1200

gaaauguuac aacaaaguaa aauacugaag guaauaagga aaaauuuagu aaaaaaaugc     1260

uuggaacuau ucacagaacu agcagaagac aaagaaaacu acaaaaaauu uuaugaacaa     1320

uucucaaaaa acauaaaguu aggaauucac gaagauagcc aaaauagaaa gaaacuaucu     1380

gaauuguuac gauauuauac auccgcauca ggugacgaaa uggugucguu aaaagauuac     1440

ugcacacgaa ugaaagaaaa ccaaaaacau auauauuaca uaacaggaga aacaaaagau     1500

caaguagcaa acagcgcauu cgucgaacga cugagaaagc acggauuaga aguaauauac     1560

augauagaac caauagauga auauugugua caacaauuaa aagaauucga aggaaaaacu     1620

cucguaucag uaacaaagga aggacuugaa cuaccagaag augaagaaga aaaaaaaaaa     1680

caagaagaaa aaaagacaaa auuugaaaac cucugcaaaa uaaugaaaga cauacuggaa     1740

aaaaaaguag aaaaaguagu agucucaaac agacuaguga ccucaccuug uuguauaguc     1800

acaagcacau auggauggac cgcaaacaug gaaagaauaa ugaaagcaca agcauuaaga     1860

gauaacucaa caauggguua cauggcagcu aaaaaacauc ucgaaauaaa uccagaucau     1920

ucuauaauag aaacucuuag acaaaaagca gaagcagaua aaaacgacaa gaguguaaaa     1980

gacuuaguca uacuauuaua cgaaacggca cuacucagca guggauuuag uuuagaagau     2040

ccacaaacac acgcgaacag gaucuacaga augauuaaac uaggauuagg aaucgaugaa     2100

gaugacccaa cagcagacga cacaucagca gcaguaacag aagaaaugcc accacuagaa     2160

ggggacgaug acacuagccg aauggaagaa guagacuaa                            2199


<210>  1345
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  1345
auggacagcu caaaacuaga cucaggaaaa ggacuacaca uaaaccuagu accaaacaaa       60

caaaaccaaa cacuaacaau aguagacaca agaauaggaa ugacaaaaac agaccuaaua      120

aacaaccuag gaacaguaac aaaaagcgga acaaaagcau ucauggaagc acuacaagca      180

gacgcagaca uaagcaugau aggacacuuc ggaguaggau ucuacucagc auaccuagua      240

gcaaaaaaag uaacaguaau aucaaaacac aacaacgacg aacaauacac augggaauca      300

agcgcaggag gaagcuucac aguaagaaca gacgaauaa                             339


<210>  1346
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  1346
augccagaag aaguacauca uggagaagaa gaagucgaaa cguuugcuuu ccaagcggaa       60

auagcgcaac uaaugagccu aauaauaaac acauucuaua guaacaaaga aaucuucuug      120

agggaauuaa uuucaaacgc cuccgaugca uuagacaaaa uaagauacga aagcuuaaca      180

gacccaucaa aauuagauag cggaaaagag cuaaaaaucg acauaauacc uaacccacaa      240

gaacguacac ugacacuugu agauacagga auaggaauga caaaagcaga ccuaauaaac      300

aaccuaggaa cuauagcuaa aucaggcacg aaagccuuca uggaagccuu acaagcagga      360

gcagauauau caaugauagg acaauuugga gugggauucu acagcgcaua ccuaguagca      420

gaaaaaguag ucguaauaac caaacauaau gacgacgaac aauacgcaug ggaaagcucg      480

gcaggaggca gcuuuacagu aagagcagau cauggcgaac cuauaggaag gggcaccaaa      540

gucauccuac aucucaaaga agaucaaaca gaauauuuag aagaaagacg agugaaagag      600

guagucaaaa agcauuccca auuuauaggc uauccaauaa ccuuauaccu agaaaaagaa      660

agagaaaaag aaauaucaga cgacgaagcc gaagaagaaa aaggagaaaa agaagaagaa      720

gauaaagacg augaagaaaa accaaaaaua gaagauguag gaagcgauga agaagacgac      780

ucaggaaaag acaaaaaaaa aaagacaaaa aaaauaaaag aaaaauauau cgaucaagaa      840

gaacucaaca aaacaaaacc cauauggaca agaaauccag acgacauaac acaggaagaa      900

uacggagaau ucuauaaaag ccuuacgaau gacugggaag aucaucuagc aguaaaacac      960

uucucuguag aaggacaacu agaauuccga gcccuacuau ucauaccaag acgcgcacca     1020

uucgaccuau ucgaaaauaa aaaaaaaaaa aacaauauaa aauuauaugu acggagagug     1080

uucauaaugg acaguugcga ugaacuaaua ccagaauacu uaaacuuuau aagaggagug     1140

guagacucag aagaccuacc ccuaaauaua agccgggaga uguuacaaca aagcaaaaua     1200

uuaaaaguaa ucaggaagaa cauuguaaaa aaaugucugg aacuauuuuc agaguuagca     1260

gaagauaaag aaaacuacaa aaaauucuac gaagcauucu caaaaaauuu aaaauuaggg     1320

auacaugaag acagcacaaa cagaagaaga cugagcgaac uacuaagaua ucauacaagu     1380

caaaguggag acgaaaugac uucacuaagu gaauacguau caagaaugaa agaaacacaa     1440

aaaucuauuu acuacauaac uggagaauca aaagaacagg uagcaaacag cgcauuuguc     1500

gaacgaguaa gaaaacgagg auucgaagua guuuauauga cagaaccuau cgaugaauau     1560

ugcguccaac aacuaaaaga auuugacgga aaaucacuug ucaguguaac aaaagaagga     1620

cuagaacugc ccgaagacga agaagaaaaa aaaaaaaugg aagaaucaaa ggcuaaauuc     1680

gaaaaucuau gcaaauuaau gaaagaaaua cucgacaaaa aaguagaaaa aguaaccaua     1740

agcaaucgac uaguaucaag uccuugcugu auagucacau caacauaugg auggacagcg     1800

aauauggaaa ggauaaugaa agcccaagca cuuagagaca auaguacaau gggauacaug     1860

auggccaaaa agcaucuaga aauaaauccu gaccacccaa ucguagaaac acuaagacaa     1920

aaagcagaag cagauaaaaa cgacaaagca guuaaagacu uaguugucuu auuauucgaa     1980

acagcacuac ucucaagugg auucucacua gaagaccccc aaacacauag uaacagaaua     2040

uaccgaauga uuaaauuggg auuaggaauc gacgaagacg aaguggcagc cgaagaacca     2100

aaugccgcag uacccgauga aauaccaccc cuagaaggag acgaagacgc aaguagaaug     2160

gaagaaguag auuaa                                                      2175


<210>  1347
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  1347
augagggcau uauggguucu aggacuaugu ugcguacuac uaacguucgg aucaguaaga       60

gcagacgaug aaguagaugu cgauggcaca guagaggaag accuaggaaa aucaagagaa      120

ggaagccgua cagacgacga aguagugcaa agagaagagg aagcaaucca guuggaugga      180

cuaaaugcaa gucaaauaag agaacuaaga gaaaaaucag aaaaauucgc auuucaagca      240

gaagugaaca gaaugaugaa acuaauaauc aauucauuau auaaaaacaa agaaauauuc      300

cugagagaac uaauaagcaa cgcaagugau gcuuuagaua aaauacgacu aauuagcuua      360

acagacgaaa augcauuaag cggaaaugaa gaguuaacag uaaaaauaaa augugacaaa      420

gaaaaaaacu uacuccaugu gacagacaca ggaguaggaa ugacccgcga ggaauuggua      480

aaaaaucuag gaacgauagc uaaaagcgga acaagugaau uucuuaauaa aaugacagaa      540

gcacaagaag acggccaauc aacaagugaa cuaauaggac aauucggagu ugguuuuuau      600

agugcuuuuu uaguugcuga caaaguaaua gucacgucga aacauaauaa cgacacacaa      660

cacaucuggg aaagugacuc gaaugaauuu ucaguuauag cagauccaag aggaaauacg      720

cuaggcagag ggacaacaau aacauuagua cuuaaagaag aagcaucaga uuauuuagaa      780

uuagauacaa uaaaaaaccu aguaaaaaaa uauagucaau ucauaaauuu ccccauauau      840

guauggagua guaaaacaga aacgguagaa gaaccaaugg aagaagaaga agcagcuaaa      900

gaagaaaaag aggaaaguga cgaugaagca gcaguugaag aagaagaaga agaaaaaaag      960

ccgaaaacua aaaaagucga aaaaacggua ugggacuggg aacuuaugaa cgauauaaag     1020

cccauauggc agagaccgag caaagaagua gaagaagaug aauauaaagc auuuuacaaa     1080

ucauuuagua aagaaucaga cgauccaaug gcuuacauac auuuuacagc cgagggagaa     1140

guaacauuca aaucaauuuu guuuguacca acaagugcuc ccagagggcu auucgaugaa     1200

uacggaucaa aaaaaagcga cuauauaaaa cucuauguaa gaagaguauu caucaccgac     1260

gacuuccacg auaugaugcc uaaauaccua aauuucguaa aaggagucgu agauagugau     1320

gacuuaccau uaaauguaag cagagaaacu cuccaacaac auaaauuacu aaaagugaua     1380

cguaaaaaau uaguaagaaa aacacucgac augauaaaaa aaauagcgga ugauaaauau     1440

aaugauacau ucuggaaaga auucggaaca aauauaaaac uuggcguaau agaagaucac     1500

ucuaauagaa caagacuagc aaaacucuua agguuccaaa gcucacauca cccaaccgau     1560

auaacuucau uagaucaaua uguagaaagg augaaagaaa aacaagauaa aauauauuuu     1620

auggcaggau caucaagaaa agaagcugaa aguagcccau ucgucgaaag acuucuuaaa     1680

aaaggguaug aaguuauaua uuugacagaa ccaguagaug aauauuguau acaggcacua     1740

ccagaauucg augguaaaag auuccaaaac guagcaaaag aaggcguaaa auucgacgaa     1800

agugagaaaa cuaaggaauc acgagaagcg guagaaaaag aauucgagcc cuuacucaau     1860

uggaugaaag acaaagcacu aaaagauaaa aucgaaaaag cuguggucag ucaaagauua     1920

acagaaucac caugcgcauu aguugcaagu caauaugggu ggucaggaaa uauggaaaga     1980

auaaugaaag cgcaagcaua ucaaacugga aaggauauau cgacuaacua cuacgcaucg     2040

caaaagaaaa cauucgaaau aaauccuaga cacccauuaa uaagagacau gcuacgaaga     2100

aucaaagaag augaagacga caagacagua cuagaucuag caguaguauu auuugaaaca     2160

gcaacauuaa gaucggguua ccuucuuccg gauacaaaag cauacggcga cagaauagaa     2220

agaaugcuca gacuaucacu caacaucgac ccagaugcaa aaguggaaga ggaaccagaa     2280

gaagaaccag aagaaacagc agaagauacg acagaagaca cugaacaaga ugaggacgaa     2340

gaaauggacg ugggaacuga cgaagaagaa gaaacugcaa aagaaagcac ugcugagaaa     2400

gaugaacuau aa                                                         2412


<210>  1348
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  1348
auggcaagag aacuaagagc ucuauuacuc uggggaagaa gacuacgacc auuauuaaga       60

gccccugcau uagcagcugu cccaggcggu aaaccuaucc uauguccaag aaggacgaca      120

gcgcaauuag gaccuagaag aaauccagcu uggagcuuac aagcagguag auuauuuagu      180

acacaaacag cagaagauaa agaagaaccu cuacauagca uaaucaguag uacagaaucu      240

guacaaggaa guacaaguaa acacgaauuu caagccgaaa caaagaaacu ccuugacauc      300

guagcuagaa gucuauauuc agaaaaagaa guauucauca gggaauuaau uucaaaugca      360

ucagaugccu uagaaaaacu aagacacaaa cugguauccg auggacaagc ccuaccagaa      420

auggagauac auuuacaaac aaacgcagaa aaagguacca ucacaaucca ggauacaggu      480

auaggcauga cucaagaaga acuuguuucu aaccuaggaa cuauagcaag aucuggcagu      540

aaagcauucc uagaugcuuu acaaaaccaa gcagaagcau cuucaaaaau aauaggacaa      600

uuugguguag gauucuauag ugcauuuaug guggcugauc guguagaagu uuauucacgg      660

ucagcagcuc caggaucauu aggauaccaa uggcuaucug augguucagg agucuucgag      720

auugcagaag cauccggagu aagaacaggc acaaaaauca uaauacaccu aaaaucugau      780

ugcaaagaau uuucuagcga agcaagagua agagauguag ucacaaaaua cuccaacuuc      840

gucucauucc cacuauacuu aaauggcaga cgaaugaaua cucuacaagc uauauggaug      900

auggauccaa aagauguccg ggaauggcaa caugaagagu ucuauagaua cguugcucaa      960

gcucacgaca aaccacgaua uacacuucau uacaaaaccg augcaccacu uaauauaaga     1020

ucaauauuuu auguaccaga caugaaacca ucuauguucg auguauccag agaauuagga     1080

ucaucuguag cauuauacuc aagaaaagug uuaauacaaa cuaaagcaac agauaucuua     1140

ccaaaauggc uucgauucau aagaggaguu guagauucag aagacauccc acuaaacuua     1200

ucgagagaau uacuacaaga aucagcacuu auuagaaaac uaagagaugu ccuacaacaa     1260

agauuaauaa aauucuuuau agaucaauca aagaaagaug cagaaaaaua cgcaaaauuc     1320

uucgaagacu auggacuauu uaugagggaa ggcauaguaa cugcaacaga acaagaaguu     1380

aaagaagaca uugcaaaacu acuaagauau gaaaguuccg cguuaccuuc aggccaacuc     1440

acgagucuaa gcgaauaugc aagccgcaug cgugcaggaa cuagaaacau auacuaccua     1500

ugugcgccua acaggcaucu cgcagaacau uccccuuacu acgaagcaau gaaaaagaaa     1560

gauacagaag uacucuucug cuucgaacaa uuugaugaac ucacauuauu acaucuacgc     1620

gaguucgaca aaaagaaauu aauauccgua gaaacagaca ucgucguaga ccacuauaaa     1680

gaagaaaaau uugaagacag aucccccgca gcagaauguu uaagugaaaa agaaacagaa     1740

gaauuaaugg cauggaugag aaacguacuu ggcucaagag uuacuaacgu uaaaguaacu     1800

cuacgacuag acacacaucc ugccauggua acggucuuag aaaugggagc agcaagacac     1860

uuccuuagaa ugcaacaauu agcaaaaacc caagaagaaa gagcacaauu acuacaacca     1920

acauuagaaa ucaauccuag gcaugcauua auaaagaaac uaaaccagcu uagagcaagc     1980

gaacccgguc uugcacaacu auuaguagau caaaucuaug aaaacgccau gauagcagca     2040

ggucuaguug acgaccccag agcaauggua gguagacuua acgaacuacu cgucaaagca     2100

uuagaaaggc auuaa                                                      2115


<210>  1349
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  1349
augggaaaaa uaucaucacu accuacacaa cuauucaaau gcugcuucug cgacuuccua       60

aaaguaaaaa ugcacacaau gucauccuca caccuauucu accuagcacu augccuacua      120

acauucacau caucagcaac agccggacca gaaacacuau gcggagcaga acuaguagac      180

gcauuacaau ucguaugcgg agacagagga uucuacuuca acaaaccaac aggauacgga      240

ucaucaucaa gaagagcacc acaaacagga auaguagacg aaugcuguuu cagaucaugc      300

gacuuaagaa gacuagaaau guacugcgca ccauuaaaac cagcaaaaag cgcaagauca      360

guaagagcac aaagacauac agacaugcca aaaacacaaa aagaaguaca ccuaaaaaac      420

gcaucaagag gaucagcagg aaacaaaaac uacagaaugu aa                         462


<210>  1350
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  1350
augggaauac caaugggaaa aucaaugcua guacuauuaa cauuucuagc cuucgcauca       60

uguugcauag cagcauacag accaagugaa acucuaugug gaggagaauu aguagauaca      120

cuacaauuug uauguggaga uagagguuuc uauuucagua gaccagcaag cagaguauca      180

agaagaagua gaggaauagu agaagaaugc uguuucagau caugugaccu agcacuacua      240

gaaacauauu gcgcaacacc agcaaaauca gaaagagaug uaucaacacc accaacagua      300

uuaccagaua acuuuccaag auacccugua ggaaaauuuu uccaauacga uacauggaaa      360

caaucaacac aaagacuaag aagaggacua ccagcacuac uaagagcaag aagaggacac      420

guacuagcaa aagaacuaga agcauuuaga gaagcaaaaa gacauagacc auuaauagca      480

uuaccaacac aagauccagc acacggagga gcaccaccag aaauggcauc aaacagaaaa      540

uaa                                                                    543


<210>  1351
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  1351
augaacucau uuucaacauc agcauucgga ccaguagcau ucucacuagg auuacuacua       60

guacuaccag cagcauuccc agccccagua ccacccggag aagacuccaa agacguagcc      120

gccccacaca gacaaccacu aacaucaucc gaaagaauag auaaacaaau aagauacaua      180

cuagacggaa ucucagcacu aagaaaagaa acaugcaaca aaucaaacau gugcgaauca      240

ucaaaagaag cacuagcaga aaacaauuua aaccuaccaa aaauggcaga aaaagacggc      300

ugcuuccaau caggauucaa ugaagaaacc ugccuaguaa aaauaauaac aggauuacuc      360

gaauucgaag uauacuuaga auaccuacaa aacagauucg aaucaucaga agaacaagca      420

agagcaguac aaaugagcac aaaaguacuc auacaauucc uacaaaaaaa agcaaaaaau      480

cuagacgcaa uaacaacacc agacccaaca acaaacgcau cacuacuaac aaaacuacaa      540

gcacaaaacc aauggcuaca agacaugaca acucaccuaa uacucagauc cuucaaagaa      600

uuucuacaau ccucacuaag agcacuaaga caaauguaa                             639


<210>  1352
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  1352
augccauuac uaugguuaag agguuuucua uuagcaucau gcuggauaau aguaagauca       60

aguccaacac caggaaguga aggucauagu gcagcaccug acuguccuag uugcgcauua      120

gcagcauuac caaaagacgu accaaacagc cagccagaaa ugguagaagc aguaaaaaaa      180

cauauauuaa auaugcuaca ucuaaaaaaa aggccagacg uaacacaacc aguaccaaaa      240

gcggcuuuau uaaaugcaau aagaaaauua cauguaggua aaguaggaga aaacgguuac      300

guagaaauag aggaugacau aggccgaaga gcagaaauga augaacuaau ggaacaaaca      360

agugaaauaa uaacauuugc agaaucagga acagcaagaa aaacgcuaca cuucgaaaua      420

agcaaagaag gaagcgaucu uaguguggua gaaagagcag aaguaugguu auuccugaag      480

guacccaaag ccaaucgaac gagaacaaaa guaacaauaa gauuauuuca acaacaaaaa      540

cauccacaag guucacuaga uacaggagag gaagccgaag aaguagguuu aaaaggagaa      600

agaucugaau uauuauuguc cgaaaaagua guagaugcca gaaaaaguac cuggcaugua      660

uuuccaguga guucaucaau acaaagauua cuagaucaag guaaaucauc acuagaugua      720

agaauagcau gugaacaaug ucaagaaagu ggagcuaguu uaguacuauu aggaaagaaa      780

aaaaaaaagg aggaagaagg agaaggaaaa aaaaaaggag gaggagaagg aggagcggga      840

gcagaugaag aaaaagaaca aagucauaga ccauucuuaa uguuacaagc aagacaaagc      900

gaagaucauc cacacagaag aagacgacga ggacuagaau gcgauggaaa agucaauaua      960

uguuguaaaa aacaauuuuu uguaucauuu aaagacauag gauggaacga uuggauaaua     1020

gcgccaucag gauaucacgc uaacuauugu gaaggagaau guccaagcca uauagcagga     1080

acgaguggaa gcucauuauc auuucacagc acgguaauaa accauuauag aaugagagga     1140

cauagcccau uugcaaauuu aaaaucaugu uguguaccua caaaacuacg uccaaugagc     1200

augcuauauu acgacgacgg acaaaauauu auaaagaaag auauccaaaa uaugauagua     1260

gaagagugcg gauguagcua a                                               1281


<210>  1353
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  1353
auggauggau uaccagggag agcauuagga gcagcauguc uauuauuauu agcagcaggu       60

ugguuaggcc cagaagcaug gggaucucca acaccaccac caacaccagc agcaccccca      120

ccaccaccac caccaggaag uccaggagga agccaagaua cauguacaag cuguggugga      180

uuuagaagac cagaagaauu aggaagagua gauggagacu uuuuagaagc cguaaaaaga      240

cacauacuuu caagauuaca aaugagagga aggccaaaua uaacacaugc aguaccaaag      300

gcagcaaugg uuacagcauu aagaaaauua cacgcaggaa aaguaagaga agaugguaga      360

guagaaauac cacauuuaga cgggcacgca ucaccaggug cagaugggca agaaagagua      420

agugagauaa uuagcuuugc agaaacagau ggauuagcau caucaagagu acgauuauau      480

uucuuuauaa guaacgaagg aaaucaaaau cuauucguag ugcaagcauc acuaugguua      540

uauuuaaaau uauugccaua uguacuagaa aaaggaagca gaagaaaggu aagaguuaaa      600

guuuauuuuc aagaacaagg ucauggagau cgauggaaua ugguagaaaa acgaguagau      660

uuaaaaagau caggauggca uacauuucca cuaacagaag caauacaagc auuauucgaa      720

agaggcgaaa gaagacugaa uuuagacgug caaugugacu caugccaaga auuagcagug      780

guuccagucu uuguagaccc aggagaagaa agccauagac cauuuguagu aguacaagca      840

agacuaggag auaguagaca uagaauaaga aaaagagguu uagaauguga cggaagaaca      900

aauuuauguu gcagacaaca auucuuuauu gauuuuaggu uaauagguug gaaugauugg      960

auaauagcac caacaggaua uuauggaaau uauugugaag gaagcugucc agcauauuua     1020

gcugguguac cagguucagc uaguaguuuu cacacagcag uagucaauca auaucguaug     1080

cgaggauuaa auccugguac uguaaauagc uguuguauac caacaaaacu aaguacaaug     1140

ucaauguuau auuuugauga ugaauauaau auaguuaaaa gagauguucc aaauaugaua     1200

guagaagaau guggaugcgc uuaa                                            1224


<210>  1354
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  1354
auggcauuac gagucuuacu uuuaacagca uuaacucugu gccacggauu uaaucuugau       60

acagaaaaug caaugacauu ucaagaaaac gcacgaggau uuggccaguc gguaguacag      120

uuacagggua gcaggguugu ugucggugcc ccacaagaaa uaguagcagc caaucaaaga      180

gguucacuau accaauguga uuacucuaca ggaaguugug agcccauaag auuacaagua      240

cccgucgaag cagucaauau gucccuagga cuaaguuuag cagcaacaac uagcccacca      300

caauuacuag cuugcggccc aaccguacac cagacauguu cugaaaauac cuaugucaaa      360

gguuuaugcu ucuuauucgg uaguaauuua agacagcaac cacaaaaauu uccugaagca      420

cuacgcggau guccucaaga agacuccgac auagcauuuc uaauagacgg aaguggcagu      480

auaauacccc augacuuuag gagaaugaaa gaauuugugu ccacaguaau ggaacaacua      540

aagaaaucua agacacuuuu cucauuaaug caauauagug aagaauuuag aauacauuuc      600

accuucaaag aauuucaaaa caacccgaau ccaagauccc uaguuaaacc aauaacccag      660

uuacuaggaa gaacacauac ugccacaggc auucgaaaag uaguacgaga acuauuuaac      720

auuacuaaug gagcuagaaa gaacgcuuuc aaaauucuag uaguuauaac ugauggagag      780

aaauucggag acccucuugg auacgaagau guuauaccag aagccgauag agaaggaguc      840

auaagauaug uaauaggagu aggcgaugcc uuccgaagcg aaaaauccag acaggaacua      900

aauacaauag cuagcaaacc accgagggac cacguuuuuc aagucaauaa uuuugaagca      960

uuaaaaacca uucaaaacca acuaagggag aaaauauucg cuauagaagg aacacaaacc     1020

ggaucuagua guagcuuuga acaugaaaug ucccaagaag guuuuucugc ugcgauaacu     1080

ucaaauggcc cacuacuauc aacagucggu aguuaugauu gggccggagg aguauuccuu     1140

uauacaagua aagaaaaauc aacauucaua aauaugacaa gaguagacuc ugauaugaau     1200

gaugccuauu uaggauacgc agcagcaauc auacuacgca acagagucca aucacucgua     1260

cuaggugccc ccagauacca acauaucggu cuggucgcua uguuucguca aaauacaggu     1320

augugggaaa guaaugcaaa uguaaaaggu acucaaauag gcgcauauuu uggugcuuca     1380

uuaugcagcg uugacgugga uucgaacggu aguacagacu uaguguuaau aggcgcaccc     1440

cacuacuacg aacaaacaag aggugggcag guaucaguau gcccucuacc cagaggccgu     1500

gccagauggc aaugugacgc aguacuauau ggagaacaag ggcaaccaug ggguagauuu     1560

ggggcugcau ugacaguuuu aggagacgua aauggagaua aacuaacgga uguugcuaua     1620

ggagccccug gugaggaaga uaauagagga gcgguauacc uauuucaugg aacaucugga     1680

aguggaauuu caccuaguca cucacaaagg auagcaggau ccaagcucuc cccacgauua     1740

caauauuuug gacagagccu aucgggaggu caagaucuaa cuauggaugg uuugguggau     1800

cucaccguag gcgcucaagg ucaugugcua cuauuacgau cacaaccugu acuuagagua     1860

aaagccauaa uggaguucaa cccaagagaa guagcucgua auguauucga augcaacgau     1920

caaguuguaa aaggcaaaga agcaggagaa gugcgugucu gucuucaugu ucagaaaagc     1980

acacgugauc gauuaagaga gggccaaauu caaucuguag uuacauacga cuuagccuua     2040

gacuccggac gaccacacuc ucgcgcaguc uuuaaugaaa cgaaaaacuc aacacgaagg     2100

caaacacaag uacuaggauu aacucaaaca ugcgaaaccc uuaaacuaca auuaccuaac     2160

uguaucgaag acccaguauc uccaaucgua uugagacuaa auuuuuccuu aguaggcaca     2220

ccacuuagug cuuuuggaaa ucuaagaccg gucuuagcag aagaugcuca aagauuauuu     2280

accgcacugu ucccauucga gaaaaacugu ggaaacgaua auauaugcca agacgacuua     2340

ucuauuacau ucucauucau gucguuagau ugucuaguag uaggaggacc cagagaauuu     2400

aauguaaccg ucacaguucg aaaugacgga gaagacucau auagaaccca aguaacauuc     2460

uucuuuccgu uagaucucag cuaucggaaa guaucaacau uacaaaacca acgaagccaa     2520

cgaucaugga ggcucgcaug ugaaagcgcu uccaguacgg aaguaagugg agcacucaaa     2580

ucuacaucuu gcucuauuaa ccacccaaua uuuccggaaa acagugaggu cacuuuuaau     2640

aucaccuucg acguagauag caaagccagu uuaggaaaua aacuucuucu caaggcaaac     2700

guaacuucug aaaauaauau gccaagaacc aacaaaacag aguuccaacu agaauuacca     2760

gucaaauacg caguauauau gguaguaaca agucauggag uuuccacgaa auaccuaaac     2820

uuuacugcau cagaaaacac aagcagagua augcaacauc aauaccaagu aucaaauuua     2880

ggacaacgaa guuuaccaau aucguuaguu uuccuggucc cagucagauu gaaucaaaca     2940

guaaucuggg auagaccaca aguaacauuu ucagaaaauc ucucaucaac cugucauacc     3000

aaggaaagau uaccuucaca uucagauuuu cuagcagaac uacgcaaagc uccaguaguu     3060

aauugcucaa ucgcaguaug ucaaagaaua caaugugaca ucccauucuu uggcauucaa     3120

gaagaauuua acgcuacauu aaaaggaaau cuuaguuuug auugguacau caaaaccagu     3180

cauaaccauu uacuaauagu cucuacugcu gaaauacuau uuaaugauuc uguauuuacu     3240

cuauuaccag gacaaggagc uuuuguucga ucacaaacag aaacuaaagu agaaccauuc     3300

gaagucccaa auccauuacc auuaaucgug gguucuucug uaggcggcuu auuacuuuua     3360

gcauuaauaa cugcugccuu guauaaauua ggauuuuuca aaaggcaaua uaaagauaug     3420

augucugaag gagguccacc cggagccgaa ccacaauaa                            3459


<210>  1355
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  1355
auguucuccc ucaaaacacu accauucuua cuacuacucc auguacaaau auccaaagca       60

uucccuguau caucaaaaga aaaaaacaca aaaacaguac aagacuaccu agaaaaauuc      120

uaccaauuac cuucaaacca auaccaauca acaagaaaaa acggaacaaa cguuauagua      180

gaaaaacuaa aagaaaugca acguuucuuu gguuuaaaug uaacagguaa accaaacgaa      240

gaaacauuag acaugaugaa aaaaccaaga uguggaguac cagacuccgg cggauuuaug      300

uuaacaccag gaaauccaaa augggaaaga acaaauuuaa cuuaccgaau aagaaacuac      360

acaccucaau uaagcgaagc agaaguagaa agagcaauaa aagaugccuu cgaacuaugg      420

uccguagcau caccucuaau uuucacaaga auaucacaag gagaagcaga caucaacaua      480

gcuuuuuauc aaagagauca cggagacaau ucaccauuug auggaccaaa cggaauccua      540

gcacaugcau uucaacccgg ucaaggaaua ggaggagacg cacacuucga ugccgaagaa      600

acauggacca acacuucagc aaacuacaac cuauuucuag uagcagcaca ugaauucggc      660

cacucauuag gacucgcuca uuccucagac ccuggagccc uaauguaucc caacuaugca      720

uucagagaaa caucaaacua uucacuaccu caagacgaca uagauggaau ucaagcuauc      780

uacggauuau caucaaaccc aauucaacca acaggaccau caacacccaa accuugugac      840

ccaucccuaa cauuugacgc uauaacaaca cuaagaggag aaauauuauu cuucaaagac      900

agauacuuuu ggagaagaca cccucaacua caaagaguug aaaugaacuu uauaucauua      960

uucuggccau cacuaccaac aggaauacaa gcagcauacg aagacuucga uagagacuua     1020

auauuccuuu ucaaaggaaa ccaauacugg gcccuaagug gauacgacau auuacaaggu     1080

uauccuaaag acauaucaaa cuacggauuu ccaucuucag uacaagcaau agacgcagca     1140

gucuucuaua gaucaaaaac auacuuuuuc guaaacgacc aauucuggag auaugacaac     1200

caacgacaau uuauggaacc aggauaucca aaaucaauau caggagcauu cccuggaaua     1260

gaauccaaag uagacgcagu auuucaacaa gaacacuucu uccauguuuu uucaggacca     1320

agauacuacg cuuuugacuu aauagcacaa agaguaacaa gaguagcaag aggaaacaaa     1380

uggcuaaacu gccgauaugg auaa                                            1404


<210>  1356
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  1356
augucauuau ggcaaccauu aguuuuggua cuuuuaguau uaggauguug uuuugcugca       60

ccacgucaaa gacaaaguac auuaguccua uuuccaggcg auuuaagaac aaauuuaaca      120

gacagacaac uugcagaaga auaucuauau agauaugguu auacaagagu agcugaaaug      180

agaggugaau caaaaucucu aggaccagca uuauuacuac uacaaaaaca guuaucacua      240

ccagaaaccg gggaacuaga cucagcuaca cuuaaagcaa ugagaacucc acggugugga      300

gucccagauc ucggucgguu ucaaacauuu gaaggagacc uuaaauggca ucaucacaau      360

auaacauauu ggauacagaa uuauucagaa gaccuaccaa gagcgguuau agacgacgca      420

uucgcccgag cauuugcacu auggagugcu guaacaccau ugacuuuuac aaggguauau      480

agucgagaug cagauaucgu aauacaauuu gguguagcag agcaugggga uggauacccu      540

uuugacggua aagacggacu ucuagcacau gcauuuccac caggaccugg aauacaagga      600

gaugcccauu uugaugacga cgaacuaugg agucuuggaa aaggagucgu aguaccuaca      660

agauuuggua augcugaugg ugcagcaugu cauuuuccuu uuauauuuga aggacgaucu      720

uacucugcau gcacuacaga uggacguuca gauggauuac caugguguuc uacuacagcc      780

aauuaugaua cagaugauag auuugguuuu uguccuucag aacgauuaua uacgcaagau      840

ggaaaugcag auggaaaacc uugucaauuc ccauuuauau uucaaggaca aucauauuca      900

gcauguacaa cagauggacg aagcgaugga uaucgauggu gugcaacaac agcuaacuac      960

gacagagaua aauuauuugg uuuuugucca acucgcgcug acucaacagu cauggguggu     1020

aauagcgcug gugaauuaug uguauuucca uuuacuuucc uuggcaaaga auacucaaca     1080

ugcacaucgg aaggaagagg agauggacga uuauggugug caacuacuag uaauuucgac     1140

agugacaaaa aauggggauu uuguccggac caaggguauu cacuuuucuu aguugcagca     1200

cacgaauucg gucaugcacu uggccuagac cauucaucag uaccugaagc ucuuauguac     1260

ccaauguaua gauuuacaga aggaccucca cuccauaaag acgaugucaa cggcauacgc     1320

caucuauaug guccacgucc agagccugaa ccaaggccuc ccacaacaac aacaccacaa     1380

ccuacugcuc caccuacagu augcccgacu ggcccaccaa caguacaucc aucugaaaga     1440

ccaacggccg gaccaacggg accuccuuca gcggguccaa caggaccacc aacagcaggc     1500

cccagcacug ccacuacagu accauuauca ccuguggacg augcuuguaa uguuaauaua     1560

uuugaugcaa uagcugaaau ugguaaucaa cuguauuuau uuaaagaugg aaaauauugg     1620

cgauuuagug aaggacgcgg aucuagaccc caaggaccau uucuaauugc cgauaaaugg     1680

ccagcccuac cuagaaaauu agauucugua uuugaagaaa gauuaucaaa aaaauuauuu     1740

uuuuucucag gaagacaagu auggguuuau acaggagcau caguacuagg accuagaaga     1800

cuagauaaac uagguuuagg agccgacguc gcacaaguua caggcgcccu aagaucagga     1860

agaggaaaaa uguuauuauu cagcgguaga agauuaugga gauuugaugu gaaagcacaa     1920

augguugauc caagaucagc uagcgaaguc gaucgaaugu ucccaggugu accauuggau     1980

acucaugaug uuuuucaaua uagagaaaaa gcauauuuuu gucaagauag auuuuauugg     2040

cguguuucau cuaggaguga auuaaaccaa guggaucaag uaggauaugu aacauacgau     2100

auacuacaau guccagaaga uuaa                                            2124


<210>  1357
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  1357
augcacccag gaguauuagc agcauuccuc uucuuaucau ggacacacug ccgagcauua       60

ccauuaccau caggaggaga cgaagacgau cuaucagaag aagaccuuca auucgcagaa      120

agauacuuaa gaucauacua ccacccaaca aacuuagcag guauacuaaa agaaaacgca      180

gccucuucaa ugacagaaag acuuagagaa augcaaucau ucuucggauu agaaguaaca      240

ggaaaauuag augacaauac acuagaugua augaaaaaac cuagaugcgg aguuccugac      300

guaggagaau auaacgucuu uccaagaaca uuaaaauggu ccaaaaugaa ccuaacauau      360

agaauaguaa acuauacacc agauaugacc cauucagaag ucgaaaaagc auucaaaaaa      420

gcauucaaag uauggucaga uguaacaccu cuaaacuuca caagacuaca ugacggaaua      480

gcagacauca ugauaagcuu uggaauaaaa gaacacggag auuucuaccc auucgacgga      540

ccaucuggau uauuagccca cgcauuuccc ccaggaccaa auuauggagg agacgcacau      600

uucgaugacg augaaacaug gacaucauca ucaaaaggau acaaccuauu cuuaguagca      660

gcacacgaau ucggacacuc uuuaggcuua gaccauucaa aagaccccgg agcacuaaug      720

uucccaauau auacauauac aggaaaaagc cacuucaugu uaccagacga ugacguccaa      780

gguauacaaa gucuauacgg accaggagau gaagauccua acccaaaaca uccaaaaacc      840

ccagacaaau gugauccauc auuaucauua gaugccauaa caucauuacg aggagaaaca      900

augauuuuca aagaccguuu cuucuggcgu cuucacccac aacaagucga cgcagaacuc      960

uuuuuaacaa aaucguuuug gccugaacua ccaaacagaa uagaugcagc auacgaacac     1020

ccuagucacg acuuaauauu uauuuuucga ggacgaaaau ucugggcccu aaauggauac     1080

gauauauuag aaggauaccc uaaaaaaaua ucugaacuag gauuaccaaa agaaguaaaa     1140

aaaauaucag ccgcagucca cuuugaagau acaggaaaaa cacuucuauu uucaggcaau     1200

caagucugga gauacgacga cacaaaccac auaauggaca aagacuaccc cagauuaaua     1260

gaagaagacu ucccaggcau aggugacaaa guagacgcag uauacgaaaa aaacggauau     1320

auauauuucu ucaacggacc aauacaauuu gaauacucua uauggucaaa cagaauagua     1380

agaguaaugc cagcaaacuc cauuuuaugg ugcuaa                               1416


<210>  1358
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  1358
auggaaacac caaacacaac agaagacuac gauacaacca cagaauuuga uuauggagac       60

gcaacaccau gucaaaaagu aaacgaaaga gccuuuggcg cgcaacuacu acccccauua      120

uacucacuag ucuucgucau aggacuagua gguaauauac uaguaguacu aguauuaguc      180

caauacaaaa gauuaaaaaa uaugacauca auauauuuac uaaacuuagc aauaucagau      240

uuacuauucc uauucacauu accauucugg aucgacuaca aacuaaaaga cgacugggua      300

uuuggagacg caaugugcaa aauacucuca ggauucuacu acacaggccu auacucugaa      360

aucuucuuca uaauacuacu aacaauagau agauaccuag caauaguuca ugcaguauuc      420

gcauuaagag ccagaaccgu cacauucgga gucauaacau caauaauaau augggccuua      480

gcaauauuag caucaaugcc aggacuauac uuuucuaaaa cacaauggga auucacacau      540

cauacaugcu cacuucacuu cccucacgaa ucccuaagag aauggaaacu cuuccaagca      600

uuaaaacuca aucuuuucgg acuaguacua ccccuacucg uaaugaucau augcuacaca      660

ggaauaauaa aaauacuacu acgacgacca aacgaaaaaa aaucaaaagc aguaagauua      720

auauucguaa uaaugaucau cuucuuccuu uuuuggaccc cuuacaaccu cacaauacua      780

auaucaguau uccaagacuu uuuauucaca cacgaaugug aacaauccag acaucucgac      840

uuagcaguac aagucaccga aguaauagca uacacacacu guugcguuaa ccccguaaua      900

uacgcuuuug uaggagaaag auuccgaaaa uaucuaagac aacuauuuca cagacgaguu      960

gcaguacacu uagucaaaug guuaccauuu cuaucaguag auagauuaga aagagucuca     1020

uccacaucac caucaaccgg agaacacgaa uuaucagcag gauucuaa                  1068


<210>  1359
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  1359
augagaacac uagcaugccu acuauuacua ggaugcggau accuagcaca uguacuagcu       60

gaagaagcag aaauaccaag agaaguaaua gaaagacuag caagaucaca aauacacuca      120

auaagagacc uacaacgacu acuagaaaua gacucagucg gaagugaaga cucacucgac      180

acaagucuaa gagcacacgg aguacacgca acaaaacacg uaccagaaaa aagaccacua      240

cccauaagaa gaaaaagaag cauagaagaa gcaguaccag caguaugcaa aacacgaaca      300

guaauauacg aaauaccaag aucacaagua gacccaacau cagcaaacuu ccuaauaugg      360

cccccaugcg uagaaguaaa aagaugcaca ggaugcugca acacaucaag cguaaaaugc      420

caaccaagca ggguacacca cagaagcguc aaaguagcaa aaguagaaua cguaagaaaa      480

aaaccaaaac uaaaagaagu acaaguaaga cuagaagaac accuagaaug cgcaugugca      540

acaacaagcc uaaauccaga uuacagagaa gaagacacag gaagaccaag agaaagcgga      600

aaaaaaagaa aaagaaaaag acuaaaacca acauaa                                636


<210>  1360
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  1360
augaacagau gcugggcauu auucuuauca uuaugcuguu accuaagauu aguaucagca       60

gaaggagauc caauaccaga agaacuauac gaaaugcuaa gcgaucacag uauaagaagc      120

uuugacgauc uacaaagauu acuucacggc gauccaggag aagaagacgg agcagaauua      180

gaccuaaaua ugacaagauc acacucagga ggagaauuag aaucacuagc acguggaaga      240

agaagccuag gaagucuaac aauagcagaa ccugcaauga uagcagaaug uaaaacacga      300

acagaaguau ucgaaauauc aagaagauua auagauagaa caaaugcaaa uuucuuagua      360

uggccaccau guguagaagu acaaagaugc aguggaugcu gcaauaacag aaacguacaa      420

uguagaccaa cacaaguaca auuaagacca guacaaguaa gaaaaauaga aauaguaaga      480

aaaaaaccaa uauuuaaaaa agcaacaguc acauuagagg accaccucgc augcaaaugu      540

gaaaccguag cagcagcaag accaguaaca agaagcccag gcggaagcca agaacaaaga      600

gcaaaaacac cacaaacuag aguuacaaua agaacaguaa gaguacgaag gcccccaaaa      660

ggaaaacaua gaaaauucaa acacacacac gacaaaacag cacuaaaaga aacacuagga      720

gcguaa                                                                 726


<210>  1361
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  1361
augucauuau uuggauuauu acuacuuaca ucagcauuag caggacaaag acaagguaca       60

caagcagaaa gcaaucuauc aagcaaauuc caauuuucau ccaauaaaga acaaaaugga      120

guacaagacc cacaacacga aagaauaaua accgucagca caaacggcuc aauacauagu      180

ccacgauucc cacauacaua uccaagaaac accguacucg ucuggagauu aguagcaguu      240

gaagaaaaug uauggaucca auuaacauuc gacgaaagau uuggauuaga agacccugaa      300

gacgacauau gcaaauacga cuuuguagaa guagaagaac caucagacgg aacaauauua      360

ggacgauggu gcggaucagg uacaguaccu gguaaacaaa ucucaaaagg caaccaaaua      420

agaauaagau ucguaagcga ugaauacuuc ccaagugaac caggauucug uauacauuac      480

aauaucguca ugccacaauu cacagaagca guaucaccau caguacuacc accaucagcu      540

cuaccauuag acuuacuaaa uaacgcuaua acagcauuuu caacauuaga agacuuaaua      600

cgauacuuag aaccagaaag auggcaacua gaccuagaag accuauacag gccaacaugg      660

caacuucuag gaaaagcauu uguauuugga agaaaaucac gaguugucga ucuaaaccua      720

uuaacagaag aaguaagacu uuacucaugc acaccaagaa acuuuucagu auccauaaga      780

gaagaacuaa aaagaacaga uacaauauuc uggccaggau gccuacuagu aaaaagaugc      840

ggcggaaauu gcgcaugcug cuuacacaac uguaacgaau gccaaugcgu accaucaaaa      900

guuacaaaaa aauaccacga aguacuacaa uuaagaccca aaacuggagu uagaggacua      960

cauaaaucuc uaacagacgu agcacuagaa caucacgaag aaugugacug cguuugccga     1020

ggaagcacag gaggcuaa                                                   1038


<210>  1362
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  1362
augcacagau uaauauuugu auacacacua auaugugcaa acuucugcuc augcagagac       60

acauccgcaa cuccacaauc agcaucaaua aaagcuuuaa gaaacgcaaa ucuaagaaga      120

gacgaucuau acagaagaga cgaaaccaua caaguaaaag gaaacggcua cguacaaagc      180

ccacgauucc cuaacucaua cccaagaaau cuauuauuaa cauggcgacu acacucccaa      240

gaaaacacaa gaauacaacu aguauucgau aaccaauucg gauuagaaga agcagaaaac      300

gacauaugua gauaugauuu cguagaagua gaagacauau cagaaacauc aacuauaaua      360

cgaggaagau ggugcggaca caaagaagua ccaccacgaa uaaaaucaag aacaaaccaa      420

auaaaaauaa cuuucaaauc agaugacuac uucguugcaa aacccggauu caaaauauau      480

uauagccuac uagaagacuu ccaaccagca gcagcuucag aaacaaauug ggaaucaguc      540

acaagcucaa uaucaggagu aucauauaau agcccaucag uuacagaccc aacacuaauc      600

gccgacgcau uagacaaaaa aauagcagaa uucgauacag uagaagaucu acuaaaauac      660

uuuaacccug aaucauggca agaagaucua gaaaacaugu aucuagacac acccagauac      720

agaggaagaa gcuaccacga cagaaaauca aaaguagacu uagacagacu aaaugaugac      780

gcaaaaagau acucaugcac accaagaaac uacagcguaa auauaagaga agaacuaaaa      840

uuagcaaacg uaguauucuu cccaagaugu cuauuaguac aacgcugcgg aggaaacugu      900

ggaugcggaa caguaaacug gcgaagcugu acaugcaauu ccggaaaaac agucaaaaaa      960

uaccacgaag uacuacaauu cgaacccgga cauauaaaaa gaagagguag agcaaaaaca     1020

auggcacuag uagauauaca auuagaccac caugaaagau gcgauuguau augcagcucu     1080

agaccuccaa gauaa                                                      1095


<210>  1363
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  1363
auggucaccc auucaaaauu cccagcagca ggaaugucaa gaccauuaga cacaucauua       60

cgauuaaaaa cauucucauc aaaaucagaa uaccaacuag uaguaaaugc aguaagaaaa      120

cuacaagaau caggauucua uuggucagca guaacaggag gagaagcaaa uuuauuacua      180

ucagcagaac cagcaggaac uuuccuaaua cgagacucau cagaccaacg acacuucuuu      240

acucuaucag uaaaaacaca aucaggaaca aaaaaccuca gaauacaaug ugaaggagga      300

ucauucuccc uacaaucaga ccccagauca acacaacccg uaccaagauu cgacugcgua      360

cuaaaacuag uacaccacua caugccacca cccggagcac cauccuuccc aucuccacca      420

acagaaccau caucugaagu accugaacaa ccaucagcac aaccacuacc uggaucacca      480

ccaagaagag cauacuacau auacucagga ggagaaaaaa uaccacuagu acuuucaaga      540

ccacuaucau cuaauguagc aacacuacaa cacuuaugcc gaaaaacagu aaacggccac      600

cuagacucau acgaaaaagu cacacaacua ccaggaccaa uaagagaauu cuuagaucaa      660

uacgacgcac cacuauaa                                                    678


<210>  1364
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  1364
augguaccau cagcaggaca auuagcauua uuugcacuag gaauaguacu agcagcaugu       60

caagcauuag aaaacucaac aucaccacua ucagcagacc caccaguagc agcagcagua      120

guaucacauu uuaaugauug cccagacuca cacacacaau ucugcuuuca cggaacaugu      180

agauuucuag uacaagaaga caaaccagca uguguauguc auucaggaua uguaggagca      240

agaugugaac augcagauuu auuagcagua guagcagcau cacaaaaaaa acaagcaaua      300

acugcauuag uaguaguaag uauaguagca uuagcaguau uaauaauaac auguguauua      360

auacauugcu gucaaguaag aaaacauugu gaauggugca gagcauuaau auguagacau      420

gaaaaaccuu cagcauuacu aaaaggaaga acagcaugcu gucacucaga aacaguagua      480

uaa                                                                    483


<210>  1365
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  1365
augccaccau caggucuacg acuacuaccu cucuuacuac cuuuacuaug gcuccucgua       60

cuaaccccag gccgaccagc agcuggccua ucaacaugca aaacaauaga cauggaauua      120

gucaaaagaa aaagaauaga agcaauuaga ggacaaauac uaucaaaauu aagauuagcc      180

uccccaccuu cucaaggaga aguaccacca gguccacuac cugaagcagu ccuagcacua      240

uacaacucaa caagagacag aguagcagga gaauccgcag aaccagaacc cgaaccagaa      300

gcagacuauu augcaaaaga agucaccaga guacuaaugg uagaaacaca uaaugaaauc      360

uacgauaaau uuaaacaauc aacacauuca auauacaugu uuuucaacac aagugaacua      420

agagaagcag uaccagaacc aguauuacua ucacgagccg aauuaagacu ccuaagacuu      480

aaacuaaaag uagaacaaca cguugaauua uaccaaaaau acucuaacaa cucauggaga      540

uacuuaucua aucgacuacu agcacccuca gacucaccag aauggcucuc auucgacgua      600

accggaguag uacgacaaug gcuaucccgu ggcggugaaa uagaaggauu cagacuaucc      660

gcacacugcu cuugcgacuc aagagacaau acauuacaag uagauauaaa cggauucaca      720

acaggaagaa gaggagacuu agcuacaauc cacggaauga accgccccuu ccuacuauua      780

auggcaacuc cucuagaaag agcacaacac uuacaauccu caagacacag aagagcacua      840

gacacaaacu auuguuucuc aagcacugaa aaaaacugcu gcguccgaca auuauacaua      900

gacuuccgaa aagaucucgg auggaaaugg auacacgaac caaaaggaua ccacgccaac      960

uucugccucg guccaugucc auauaucugg ucacuagaua cacaauacuc caaaguacua     1020

gcauuauaua accaacauaa uccaggagca ucagcagcgc caugcugcgu accacaagca     1080

uuagaaccac ucccaauagu auacuauguc ggaagaaaac caaaaguaga acaacuauca     1140

aacaugauag ucagaucaug caaauguucu uaa                                  1173


<210>  1366
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  1366
augcacuauu gcguacuuuc agcauuucua auauuacacc uaguaacagu cgcuuuaagu       60

uuaagcacau gcucaaccuu agacauggac caauuuauga gaaaacgaau agaagcaaua      120

agaggacaaa uauuauccaa acuaaaacua acaucaccac ccgaagauua uccagaacca      180

gaagaagucc caccagaagu aauaucaaua uauaacagca caagagaccu ccuacaagaa      240

aaagcaucaa gaagagcagc agcaugcgaa cgagaaagau cagaugaaga auauuacgcu      300

aaagaaguau acaaaauaga caugcccccc uucuuuccau cagaaaaugc aauaccacca      360

accuuuuaca gacccuauuu ucgaauagua agauucgaug uaucagccau ggaaaaaaac      420

gcaucaaacc uagucaaagc ggaauucaga guauuccgac uucaaaaccc aaaagcuaga      480

guucccgaac aacgaaucga acuauaucaa auacuaaaau caaaagaccu aaccucaccc      540

acacaaagau acauagacuc aaaaguagua aaaaccagag cagagggcga augguuauca      600

uucgacguaa cagacgcagu acacgaaugg cuacaucaca aagaccgaaa ucucggauuc      660

aaaauaucac uacacugccc augcugcaca uucgucccau caaacaacua uauaauacca      720

aauaaaucag aagaacuuga agcaagauuu gcuggaauag acggaacaag uacauacacc      780

ucuggagacc aaaaaacuau aaaaucaaca agaaaaaaaa acucuggcaa aacaccucac      840

cuacuauuaa ugcuacuacc cucauacaga cuagaaucac aacaaacaaa ccgaagaaaa      900

aaaagagcac uagacgcagc auacuguuuc agaaacguac aagauaacug cugccucaga      960

ccacuauaua uagacuucaa aagagaccua ggauggaaau ggauacauga accaaaaggc     1020

uacaacgcca acuucugcgc aggagcaugc ccauacuuau ggucaucuga cacacagcac     1080

ucaagaguac uaucacuaua caacacaaua aauccagaag cuucagcaag ucccugcugc     1140

guaucacaag acuuagaacc cuuaacuaua uuauauuaua ucggaaaaac accaaaaaua     1200

gaacaacuau caaacaugau aguaaaauca uguaaaugua guuaa                     1245


<210>  1367
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  1367
augaaaaugc accuccaaag agcccucguc guucucgcac uacuaaacuu cgcaaccgua       60

ucacuauccc uaucaacaug cacaacccua gacuucggac acauaaaaaa aaaaagagua      120

gaagcaaucc gaggccaaau uuuaucaaaa cuaagacuaa caucaccacc agaacccaca      180

gucaugacac acguaccaua ccaaguccua gcacuauaca acucaacacg agaacuauua      240

gaagaaaugc acggagaaag agaagaagga uguacacaag aaaacacuga aagugaauac      300

uaugcaaaag aaauacacaa auucgauaug auacaaggac uagcagaaca caacgaacua      360

gcaguaugcc caaaaggaau aacaucaaaa guauuucgau ucaacguauc aucaguagag      420

aaaaaucgaa caaaccuauu uagagccgaa uuuagagucc uaagaguccc caauccauca      480

ucaaaaagaa acgaacaacg cauagaacua uuucaaauac uacgcccaga cgaacacaua      540

gcaaaacaaa gauacauagg uggaaaaaac cucccaacca gaggaacagc cgaauggcua      600

ucauucgacg uaacagacac cgucagagaa uggcuacucc gcagagaauc aaacuuaggu      660

cuagaaauau caauacacug cccaugccau acauuucaac caaauggaga cauauuagaa      720

aacauacaug aaguaaugga aaucaaauuc aaaggaguag acaacgaaga cgaccacgga      780

cgaggcgacc ucggcagacu aaaaaaacaa aaagaucacc acaauccaca ccuaauccua      840

augaugauac ccccccacag acuagacaac ccaggacaag gaggacaacg aaaaaaaaga      900

gcacucgaca caaauuauug uuuccgaaau cuagaagaaa acugcugcgu ccguccacuu      960

uacauagacu ucagacaaga ccuaggaugg aaauggguuc acgaaccaaa aggauauuau     1020

gccaacuucu gcucaggacc cugcccauac uuaagaucag cagacacaac acacucuaca     1080

guacuaggac uauacaacac acuaaaccca gaagccucag caucacccug cuguguccca     1140

caagaccuag aaccuuuaac cauacuauac uacguaggaa gaacuccuaa aguagaacaa     1200

cuuucaaaua ugguaguaaa aucaugcaaa ugcucauaa                            1239


<210>  1368
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  1368
auggcaccag uagcaguaug ggcagcacuu gcaguaggac ucgaauuaug ggcagcagca       60

caugcauuac cugcacaagu ugcauucaca cccuacgcac ccgaaccagg cucaaccugu      120

agauuaagag aauauuacga ucaaacagcu caaaugugcu guucuaaaug cucaccuggc      180

caacaugcaa aaguauuuug cacuaaaaca ucugauaccg uaugugauuc uugugaagac      240

ucaacauaua cacaacuaug gaacuggguu ccagaauguc uaucaugcgg aucaagaugu      300

ucaucagacc aaguugaaac acaagcaugu acucgugaac aaaaucgaau uugcacaugu      360

agaccaggau gguauugcgc uuuaucgaaa caagaaggau guagacuaug cgcaccucuu      420

agaaaaugca gaccaggcuu uggagucgcu cgacccggaa cugaaacauc agacguagua      480

ugcaaaccuu gugcaccagg uacauucucu aacacaacaa guucaacaga uauuuguaga      540

ccacaccaaa uauguaacgu aguugcuaua ccaggaaacg caucuaugga ugcaguaugu      600

acaucuacgu caccuaccag aucaauggca ccaggagcag uucacuuacc acaaccagua      660

ucaacaagaa gucaacacac acaaccaaca ccugaacccu caacugcacc aagcacuuca      720

uuucuacuac caaugggucc cucaccaccu gcugaaggau caacaggaga cuucgcauua      780

ccugucggac uuaucguagg aguuacagca uuaggacuau uaauaaucgg uguaguaaau      840

uguguuauua ugacacaagu aaaaaaaaaa cccuuauguu uacaaagaga agccaaagua      900

ccucauuuac cagcagauaa agccagagga acccaagguc cagaacaaca acauuuauua      960

aucacagcuc ccucaucauc aucaucaucu uuagaaucau cagcaagugc ucuagauaga     1020

agagcuccca caagaaacca accucaagca ccaggugucg aagcaucagg agcuggugaa     1080

gcucgugcuu cuacgggauc uucagauuca ucacccggag gacacggaac acaaguaaau     1140

guaacaugca uaguaaaugu cuguuccagu ucggaucauu caucacaaug uucaucacaa     1200

gcaucaucua cuaugggaga uacagauagu ucaccaucag aauccccaaa agacgaacaa     1260

guaccauuuu caaaagaaga augcgcauuu agaucacaau uagaaacacc agaaacauua     1320

uuaggaucaa cugaagaaaa accacuacca cuaggcguac cagaugcagg aaugaaaccc     1380

ucauaa                                                                1386


<210>  1369
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  1369
augccaguaa ugagauuauu uccauguuuc uuacaauuau uagcaggauu agcauuacca       60

gcaguaccac cacaacaaug ggcguuauca gcaggaaaug gaaguaguga aguagaagua      120

guaccauuuc aagaaguaug gggaagauca uauuguagag cacuagaaag acuaguagau      180

guaguaagug aauauccaag cgaaguagaa cauauguuuu caccaucaug uguaaguuua      240

uuaagaugua cgggaugcug uggagaugaa aauuuacauu guguaccagu agaaacagca      300

aauguaacaa ugcaauuauu aaaaauaaga aguggagaua gaccaucaua uguagaauua      360

acauuuagcc aacauguaag augugaaugu agaccauuaa gagaaaaaau gaaaccagaa      420

agaagaagac caaaaggaag aggaaaaaga agaagagaaa aacaaagacc aacagauugu      480

cauuuaugug gagaugcagu accaagaaga uaa                                   513


<210>  1370
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  1370
augacagaua gacaaacaga uacagcgcca aguccaucau accauuuauu accaggaaga       60

agaagaacag uagaugcagc agcgaguaga ggacaaggac cagagccagc accaggagga      120

ggaguagaag gaguuggagc aagaggagua gcgcuaaaau uauuuguaca acuauuagga      180

ugcaguagau ucgguggagc aguaguaaga gcuggagaag cagaaccauc cggugcagcc      240

agaagcgcaa guaguggaag agaagaacca caaccagaag aaggagaaga agaagaagaa      300

aaagaagagg aaagaggacc acaauggaga cuuggcgcua gaaaaccugg gagcuggaca      360

ggagaagcag cuguaugcgc agauagugca ccagcagcaa gagcaccaca agcauuagca      420

agagcaucag gacgaggagg aagaguagca agaaggggag ccgaagaaag uggaccucca      480

cauaguccaa guagaagagg aucagcaagu agagcugggc caggaagggc aucugaaaca      540

augaauuuuu uauuaaguug gguacauugg aguuuagcuu uauugcuaua uuuacaucac      600

gcaaaaugga gucaagcagc accaauggca gaaggagggg gacaaaauca ucacgaagua      660

guaaaauuua uggauguuua ucaaaggagu uauugucauc cuauagaaac guuaguagau      720

auauuucaag aauacccaga ugaaauagag uauauauuua aaccgaguug uguaccauua      780

augagaugug gaggauguug uaaugacgaa ggacuagaau guguaccaac agaagaaagc      840

aauauaacua ugcagauaau gagaauaaaa ccucaucaag gacaacauau aggagaaaug      900

aguuuuuugc aacacaauaa gugcgaaugu agaccaaaaa aagaucgagc aagacaagaa      960

aaaaaaagcg uaagagguaa agguaaagga caaaaaagaa aaagaaaaaa aaguagauau     1020

aaaagcugga guguauacgu aggggcaaga uguuguuuga ugccauggag ccucccagga     1080

ccucauccgu guggaccaug uucagagaga agaaaacauc uguuuguaca agauccacaa     1140

acauguaaau gcaguugcaa aaauacggau ucaagaugua aagcgagaca auuagaauua     1200

aaugaaagga cauguagaug cgauaagccg agaagauaa                            1239


<210>  1371
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  1371
augaacuucu uacuaucaug gguacauugg agcuuagcac uauuacuaua ccuacaccac       60

gcaaaauggu cacaagcagc accaauggca gaaggaggag gacaaaacca ccaugaagua      120

guaaaauuca uggauguaua ccaaagauca uacugccacc caauagaaac acuaguagac      180

auauuccaag aauacccaga cgaaauagaa uacauauuca aaccaucaug uguaccauua      240

augagaugcg gaggaugcug caacgacgaa ggacuagaau guguaccaac agaagaaagu      300

aacauaacaa ugcaaauaau gagaauaaaa ccacaucaag gacaacacau aggagaaaug      360

agcuuccuac aacacaauaa augcgaaugc agaccaaaaa aagacagagc aagacaagaa      420

aaaaaaagug uaagaggaaa aggaaaagga caaaaaagaa aaagaaaaaa aucaagauac      480

aaaucauggu caguauacgu aggagcaaga ugcugccuaa ugccaugguc acuaccagga      540

ccacacccau gcggaccaug cucagaaaga agaaaacacc uauucguaca agacccacaa      600

accugcaaau gcaguugcaa aaacacagac agcagaugca aagcaagaca auuagaacua      660

aacgaaagaa caugcagaug cgauaaacca cgaagauaa                             699


<210>  1372
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  1372
augucaccac uauuaagaag auuauuacua gcagcauuac uacaauuagc acccgcacaa       60

gcaccuguau cacaaccaga ugcaccagga caucaaagaa aaguaguauc auggauagac      120

guauacacaa gagcaacaug ucaaccaaga gaaguaguag uaccauuaac aguagaacua      180

augggaacag ucgcaaaaca acuaguacca ucaugcguaa caguacaaag augcggaggc      240

uguuguccag acgauggauu agaauguguu ccaacaggac aacaucaagu aagaaugcaa      300

auacuaauga uaagauaccc aucaucucaa cuaggagaaa uguccuuaga agaacauagu      360

caaugcgaau gcagaccaaa aaaaaaagau ucagcaguaa aaccagaccg agcagcaaca      420

ccacaucaua gaccacaacc acgaucagua ccaggcuggg acucagcccc aggagcacca      480

ucaccagcag auauaaccca ucccacaccu gcaccaggac caucugcaca ugcagcaccu      540

ucaacaacau cagcauuaac accaggacca gcagcagcag ccgcagacgc agcugcauca      600

ucaguagcaa aaggaggagc auaa                                             624


<210>  1373
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  1373
augcaccucu uaggauucuu cucaguagcu ugcucauuau uagccgccgc cuuauuacca       60

ggaccaagag aagcaccagc agcagccgca gcauuugaau caggauuaga cuuaagugau      120

gcugaaccag acgcaggaga agcuacagca uaugccagua aagacuuaga agaacaauua      180

agaucaguaa guuccguaga cgaauuaaug acaguacucu auccagaaua cuggaaaaug      240

uauaaauguc aacuaagaaa aggcggaugg caacauaaua gggaacaagc aaaucuaaau      300

ucaagaacag aagaaacuau aaaauucgca gccgcacacu auaacacgga aauacuaaaa      360

aguauagaua acgaauggag aaaaacacaa ugcaugccaa gagaaguaug cauagaugua      420

ggaaaagaau uuggaguagc aacaaacaca uuuuucaaac caccaugugu aagcguauac      480

agauguggcg guugcugcaa uagcgaagga uuacaaugua ugaacacuag cacuucauac      540

uuaucaaaaa cacuauuuga aauuacagua ccauuaaguc aaggaccuaa accaguaacg      600

auaaguuuug caaaccacac aucauguaga uguaugucaa aacuagaugu auauagacaa      660

guacacucaa uaauaagaag aucacuacca gcaacacuuc cacaaugcca agcagcaaau      720

aaaacauguc caacaaacua uauguggaac aaccacauau gcagaugucu agcacaagaa      780

gauuucaugu uuaguucaga cgcaggagac gacagcacag auggauuuca ugacauaugc      840

ggacccaaca aagaauuaga cgaagaaacu ugucaaugcg uauguagagc aggacuacga      900

ccagcaucau guggaccaca uaaagaauua gacagaaaca guugccaaug cguaugcaaa      960

aauaaacuau ucccaucaca auguggagca aaucgagaau uugaugaaaa cacaugucaa     1020

uguguaugca aaagaacaug cccaagaaau caaccauuaa auccagguaa augcgcaugu     1080

gaauguacag aaucaccaca aaaaugccua uuaaaaggaa agaaauuuca ccaucaaaca     1140

ugcaguuguu auagaagacc auguacaaau agacaaaaag ccugugaacc aggauucucc     1200

uacucagaag aaguauguag auguguacca aguuacugga aaagaccaca aaugucauaa     1260


<210>  1374
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  1374
auguaccgag aauggguagu aguaaacgua uucaugaugc uuuacguaca acuaguacaa       60

ggaucaucaa augaacacgg accaguaaaa agaucaagcc aaucaacauu agaaagauca      120

gaacaacaaa uacgagcagc aucaucacuc gaagaacucc uaagaauaac acacuccgaa      180

gacuggaaac uauggcgaug cagacuaaga uuaaaaucau ucacaucaau ggauucacgc      240

uccgcauccc acagaucaac aagauuugcc gccacauuuu acgacauaga aacauuaaaa      300

gucaucgacg aagaauggca acgaacacaa ugcucaccua gagaaacaug cguagaagua      360

gcaucagaac uagguaaauc cacaaauacc uuuuuuaaac caccuugcgu aaacguauuc      420

agaugcggag gcuguugcaa cgaagaauca cuaauuugua ugaacacauc uacauccuac      480

auaucaaaac aacuauucga aauaucagua ccacuaacaa gcguacccga acuagucccc      540

guaaaaguag caaaccacac aggaugcaaa ugccuaccaa cagcaccaag acauccauac      600

uccauaauac gaagaucaau acaaauacca gaagaagaca gaugcucaca cucaaaaaaa      660

cuaugcccua uagauaugcu augggacagc aacaaaugca aaugcguacu acaagaagaa      720

aacccucuag caggaaccga agaccacagc caucuacaag aaccagcauu augcggucca      780

cauaugaugu ucgacgaaga cagaugcgaa ugcguaugca aaacaccaug ccccaaagac      840

cuuauacaac acccuaaaaa cuguagcugc uuugaaugca aagaaucacu agaaacaugc      900

ugccaaaaac acaaauuauu ucacccagac acaugcucau gcgaagacag augcccauuc      960

cacaccagac caugcgcauc cgguaaaaca gcaugugcaa aacacugcag auuccccaaa     1020

gaaaaaagag cagcccaagg accacacuca agaaaaaauc cauaa                     1065


<210>  1375
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (wt)

<400>  1375
gggagaaagc uuaccaugga cucggacgag accggguucg agcacucagg acuguggguu       60

ucugugcugg cuggucuucu gcugggagcc ugccaggcac accccauccc ugacuccagu      120

ccucuccugc aauucggggg ccaaguccgg cagcgguacc ucuacacaga ugaugcccag      180

cagacagaag cccaccugga gaucagggag gaugggacgg uggggggcgc ugcugaccag      240

agccccgaaa gucuccugca gcugaaagcc uugaagccgg gaguuauuca aaucuuggga      300

gucaagacau ccagguuccu gugccagcgg ccagaugggg cccuguaugg aucgcuccac      360

uuugacccug aggccugcag cuuccgggag cugcuucuug aggacggaua caauguuuac      420

caguccgaag cccacggccu cccgcugcac cugccaggga acaagucccc acaccgggac      480

ccugcacccc gaggaccagc ucgcuuccug ccacuaccag gccugccccc cgcacucccg      540

gagccacccg gaauccuggc cccccagccc cccgaugugg gcuccucgga cccucugagc      600

auggugggac cuucccaggg ccgaagcccc agcuacgcuu ccugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  1376
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (wt)

<400>  1376
gggagaaagc uuaccaugga cucggacgag accggguucg agcacucagg acuguggguu       60

ucugugcugg cuggucuucu gcugggagcc ugccaggcac accccauccc ugacuccagu      120

ccucuccugc aauucggggg ccaaguccgg cagcgguacc ucuacacaga ugaugcccag      180

cagacagaag cccaccugga gaucagggag gaugggacgg uggggggcgc ugcugaccag      240

agccccgaaa gucuccugca gcugaaagcc uugaagccgg gaguuauuca aaucuuggga      300

gucaagacau ccagguuccu gugccagcgg ccagaugggg cccuguaugg aucgcuccac      360

uuugacccug aggccugcag cuuccgggag cugcuucuug aggacggaua caauguuuac      420

caguccgaag cccacggccu cccgcugcac cucccaggga acaagucccc acaccgggac      480

ccugcacccc gaggaccagc ucgcuuccug ccacuaccag gccugccccc cgcacucccg      540

gagccacccg gaauccuggc cccccagccc cccgaugugg gcuccucgga cccucugagc      600

auggugggac cuucccaggg ccgaagcccc agcuacgcuu ccugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  1377
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (wt)

<400>  1377
gggagaaagc uuaccaugca cagcuuuccu ccacugcugc ugcugcuguu cuggggugug       60

gugucucaca gcuucccagc gacucuagaa acacaagagc aagaugugga cuuaguccag      120

aaauaccugg aaaaauacua caaccugaag aaugauggga ggcaaguuga aaagcggaga      180

aauaguggcc cagugguuga aaaauugaag caaaugcagg aauucuuugg gcugaaagug      240

acugggaaac cagaugcuga aacccugaag gugaugaagc agcccagaug uggagugccu      300

gauguggcuc aguuuguccu cacugagggg aacccucgcu gggagcaaac acaucugacc      360

uacaggauug aaaauuacac gccagauuug ccaagagcag auguggacca ugccauugag      420

aaagccuucc aacucuggag uaaugucaca ccucugacau ucaccaaggu cucugagggu      480

caagcagaca ucaugauauc uuuugucagg ggagaucauc gggacaacuc uccuuuugau      540

ggaccuggag gaaaucuugc ucaugcuuuu caaccaggcc cagguauugg aggggaugcu      600

cauuuugaug aagaugaaag guggaccaac aauuucagag aguacaacuu acaucguguu      660

gcagcucaug aacucggcca uucucuugga cucucccauu cuacugauau cggggcuuug      720

auguacccua gcuacaccuu caguggugau guucagcuag cucaggauga cauugauggc      780

auccaagcca uauauggacg uucccaaaau ccuguccagc ccaucggccc acaaacccca      840

aaagcgugug acaguaagcu aaccuuugau gcuauaacua cgauucgggg agaagugaug      900

uucuuuaaag acagauucua caugcgcaca aaucccuucu acccggaagu ugagcucaau      960

uucauuucug uuuucuggcc acaacugcca aaugggcuug aagcugcuua cgaauuugcc     1020

gacagagaug aaguccgguu uuucaaaggg aauaaguacu gggcuguuca gggacagaau     1080

gugcuacacg gauaccccaa ggacaucuac agcuccuuug gcuucccuag aacugugaag     1140

cauaucgaug cugcucuuuc ugaggaaaac acuggaaaaa ccuacuucuu uguugcuaac     1200

aaauacugga gguaugauga auauaaacga ucuauggauc cagguuaucc caaaaugaua     1260

gcacaugacu uuccuggaau uggccacaaa guugaugcag uuuucaugaa agauggauuu     1320

uucuauuucu uucauggaac aagacaauac aaauuugauc cuaaaacgaa gagaauuuug     1380

acucuccaga aagcuaauag cugguucaac ugcaggaaaa auugaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  1378
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (wt)

<400>  1378
gggagaaagc uuaccaugca cagcuuuccu ccacugcugc ugcugcuguu cuggggugug       60

gugucucaca gcuucccagc gacucuagaa acacaagagc aagaugugga cuuaguccag      120

aaauaccugg aaaaauacua caaccugaag aaugauggga ggcaaguuga aaagcggaga      180

aauaguggcc cagugguuga aaaauugaag caaaugcagg aguucuuugg gcugaaagug      240

acugggaaac cagaugcuga aacccugaag gugaugaagc agcccagaug uggagugccu      300

gauguggcuc aguuuguccu cacugagggg aacccucgcu gggagcaaac acaucugacc      360

uacaggauug aaaauuacac gccagauuug ccaagagcag auguggacca ugccauugag      420

aaagccuucc aacucuggag uaaugucaca ccucugacau ucaccaaggu cucugagggu      480

caagcagaca ucaugauauc uuuugucagg ggagaucauc gggacaacuc uccuuuugau      540

ggaccuggag gaaaucuugc ucaugcuuuu caaccaggcc cagguauugg aggggaugcu      600

cauuuugaug aagaugaaag guggaccaac aauuucagag aguacaacuu acaucguguu      660

gcagcucaug aacucggcca uucucuugga cucucccauu cuacugauau cggggcuuug      720

auguacccua gcuacaccuu caguggugau guucagcuag cucaggauga cauugauggc      780

auccaagcca uauauggacg uucccaaaau ccuguccagc ccaucggccc acaaacccca      840

aaagcgugug acaguaagcu aaccuuugau gcuauaacua cgauucgggg agaagugaug      900

uucuuuaaag acagauucua caugcgcaca aaucccuucu acccggaagu ugagcucaau      960

uucauuucug uuuucuggcc acaacugcca aaugggcuug aagcugcuua cgaauuugcc     1020

gacagagaug aaguccgguu uuucaaaggg aauaaguacu gggcuguuca gggacagaau     1080

gugcuacacg gauaccccaa ggacaucuac agcuccuuug gcuucccuag aacugugaag     1140

cauaucgaug cugcucuuuc ugaggaaaac acuggaaaaa ccuacuucuu uguugcuaac     1200

aaauacugga gguaugauga auauaaacga ucuauggauc cagguuaucc caaaaugaua     1260

gcacaugacu uuccuggaau uggccacaaa guugaugcag uuuucaugaa agauggauuu     1320

uucuauuucu uucauggaac aagacaauac aaauuugauc cuaaaacgaa gagaauuuug     1380

acucuccaga aagcuaauag cugguucaac ugcaggaaaa auugaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  1379
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (wt)

<400>  1379
gggagaaagc uuaccaugca cagcuuuccu ccacugcugc ugcugcuguu cuggggugug       60

gugucucaca gcuuuguccu cacugagggg aacccucgcu gggagcaaac acaucugacc      120

uacaggauug aaaauuacac gccagauuug ccaagagcag auguggacca ugccauugag      180

aaagccuucc aacucuggag uaaugucaca ccucugacau ucaccaaggu cucugagggu      240

caagcagaca ucaugauauc uuuugucagg ggagaucauc gggacaacuc uccuuuugau      300

ggaccuggag gaaaucuugc ucaugcuuuu caaccaggcc cagguauugg aggggaugcu      360

cauuuugaug aagaugaaag guggaccaac aauuucagag aguacaacuu acaucguguu      420

gcagcucaug aacucggcca uucucuugga cucucccauu cuacugauau cggggcuuug      480

auguacccua gcuacaccuu caguggugau guucagcuag cucaggauga cauugauggc      540

auccaagcca uauauggacg uucccaaaau ccuguccagc ccaucggccc acaaacccca      600

aaagcgugug acaguaagcu aaccuuugau gcuauaacua cgauucgggg agaagugaug      660

uucuuuaaag acagauucua caugcgcaca aaucccuucu acccggaagu ugagcucaau      720

uucauuucug uuuucuggcc acaacugcca aaugggcuug aagcugcuua cgaauuugcc      780

gacagagaug aaguccgguu uuucaaaggg aauaaguacu gggcuguuca gggacagaau      840

gugcuacacg gauaccccaa ggacaucuac agcuccuuug gcuucccuag aacugugaag      900

cauaucgaug cugcucuuuc ugaggaaaac acuggaaaaa ccuacuucuu uguugcuaac      960

aaauacugga gguaugauga auauaaacga ucuauggauc cagguuaucc caaaaugaua     1020

gcacaugacu uuccuggaau uggccacaaa guugaugcag uuuucaugaa agauggauuu     1080

uucuauuucu uucauggaac aagacaauac aaauuugauc cuaaaacgaa gagaauuuug     1140

acucuccaga aagcuaauag cugguucaac ugcaggaaaa auugaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  1380
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (wt)

<400>  1380
gggagaaagc uuaccaugaa aaaaaauauu uuaaagauuc uuauggauag uuauucuaaa       60

gaaucuaaaa uucaaacugu acguaggguu acgaguguau cacuuuuagc gguauaucuu      120

acuaugaaua cuucaaguuu aguuuuagca aaaccaauag aaaauacuaa ugauacuagu      180

auaaaaaaug uggagaaauu aagaaaugcu ccaaaugaag agaauaguaa aaagguagaa      240

gauaguaaaa augauaaggu agaacaugug aaaaauauag aagaggcaaa gguugagcaa      300

guugcacccg aaguaaaauc uaaaucaacu uuaagaagug cuucuauagc gaauacuaau      360

ucugagaaau augauuuuga guauuuaaau gguuugagcu auacugaacu uacaaauuua      420

auuaaaaaua uaaaguggaa ucaaauuaau gguuuauuua auuauaguac agguucucaa      480

aaguucuuug gagauaaaaa ucguguacaa gcuauaauua augcuuuaca agaaagugga      540

agaacuuaca cugcaaauga uaugaagggu auagaaacuu ucacugaggu uuuaagagcu      600

gguuuuuauu uaggguacua uaaugauggu uuaucuuauu uaaaugauag aaacuuccaa      660

gauaaaugua uaccugcaau gauugcaauu caaaaaaauc cuaacuuuaa gcuaggaacu      720

gcaguucaag augaaguuau aacuucuuua ggaaaacuaa uaggaaaugc uucugcuaau      780

gcugaaguag uuaauaauug uguaccaguu cuaaaacaau uuagagaaaa cuuaaaucaa      840

uaugcuccug auuacguuaa aggaacagcu guaaaugaau uaauuaaagg uauugaauuc      900

gauuuuucug gugcugcaua ugaaaaagau guuaagacaa ugccuuggua uggaaaaauu      960

gauccauuua uaaaugaacu uaaggccuua ggucuauaug gaaauauaac aagugcaacu     1020

gagugggcau cugauguugg aauauacuau uuaaguaaau ucggucuuua cucaacuaac     1080

cgaaaugaca uaguacaguc acuugaaaag gcuguagaua uguauaagua ugguaaaaua     1140

gccuuuguag caauggagag aauaacuugg gauuaugaug ggauugguuc uaaugguaaa     1200

aagguggauc acgauaaguu cuuagaugau gcugaaaaac auuaucugcc aaagacauau     1260

acuuuugaua auggaaccuu uauuauaaga gcaggggaua agguauccga agaaaaaaua     1320

aaaaggcuau auugggcauc aagagaagug aagucucaau uccauagagu aguuggcaau     1380

gauaaagcuu uagagguggg aaaugccgau gauguuuuaa cuaugaaaau auuuaauagc     1440

ccagaagaau auaaauuuaa uaccaauaua aaugguguaa gcacugauaa ugguggucua     1500

uauauagaac caagagggac uuucuacacu uaugagagaa caccucaaca aaguauauuu     1560

agucuugaag aauuguuuag acaugaauau acucacuauu uacaagcgag auaucuugua     1620

gaugguuuau gggggcaagg uccauuuuau gaaaaaaaua gauuaacuug guuugaugaa     1680

gguacagcug aauucuuugc aggaucuacc cguacaucug guguuuuacc aagaaaauca     1740

auauuaggau auuuggcuaa ggauaaagua gaucauagau acucauuaaa gaagacucuu     1800

aauucagggu augaugacag ugauuggaug uucuauaauu auggauuugc aguugcacau     1860

uaccuauaug aaaaagauau gccuacauuu auuaagauga auaaagcuau auugaauaca     1920

gaugugaaau cuuaugauga aauaauaaaa aaauuaagug augaugcaaa uaaaaauaca     1980

gaauaucaaa accauauuca agaguuagca gauaaauauc aaggagcagg cauaccucua     2040

guaucagaug auuacuuaaa agaucaugga uauaagaaag caucugaagu auauucugaa     2100

auuucaaaag cugcuucucu uacaaacacu aguguaacag cagaaaaauc ucaauauuuu     2160

aacacauuca cuuuaagagg aacuuauaca ggugaaacuu cuaaagguga auuuaaagau     2220

ugggaugaaa ugaguaaaaa auuagaugga acuuuggagu cccuugcuaa aaauucuugg     2280

aguggauaca aaacuuuaac agcauacuuu acgaauuaua gaguuacaag cgauaauaaa     2340

guucaauaug auguaguuuu ccaugggguu uuaacagaua augcggauau uaguaacaau     2400

aaggcuccaa uagcaaaggu aacuggacca agcacuggug cuguaggaag aaauauugaa     2460

uuuaguggaa aagauaguaa agaugaagau gguaaaauag uaucauauga uugggauuuu     2520

ggcgauggug caacuaguag aggcaaaaau ucaguacaug cuuacaaaaa agcaggaaca     2580

uauaauguua cauuaaaagu aacugacgau aagggugcaa cagcuacaga aagcuuuacu     2640

auagaaauaa agaacgaaga uacaacaaca ccuauaacua aagaaaugga accuaaugau     2700

gauauaaaag aggcuaaugg uccaauaguu gaagguguua cuguaaaagg ugauuuaaau     2760

gguucugaug augcugauac cuucuauuuu gauguaaaag aagaugguga uguuacaauu     2820

gaacuuccuu auucaggguc aucuaauuuc acaugguuag uuuauaaaga gggagacgau     2880

caaaaccaua uugcaagugg uauagauaag aauaacucaa aaguuggaac auuuaaaucu     2940

acaaaaggaa gacauuaugu guuuauauau aaacacgauu cugcuucaaa uauauccuau     3000

ucuuuaaaca uaaaaggauu agguaacgag aaauugaagg aaaaagaaaa uaaugauucu     3060

ucugauaaag cuacaguuau accaaauuuc aauaccacua ugcaagguuc acuuuuaggu     3120

gaugauucaa gagauuauua uucuuuugag guuaaggaag aaggcgaagu uaauauagaa     3180

cuagauaaaa aggaugaauu ugguguaaca uggacacuac auccagaguc aaauauuaau     3240

gacagaauaa cuuacggaca aguugauggu aauaagguau cuaauaaagu uaaauuaaga     3300

ccaggaaaau auuaucuacu uguuuauaaa uacucaggau caggaaacua ugaguuaagg     3360

guaaauaaau aaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  1381
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (wt)

<400>  1381
gggagaaagc uuaccaugaa aaaaaauauu uuaaagauuc uuauggauag uuauucuaaa       60

gaaucuaaaa uucaaacugu acguaggguu acgaguguau cacuuuuagc gguauaucuu      120

acuaugaaua cuucaaguuu aguuuuagca aaaccaauag aaaauacuaa ugauacaagu      180

auaaaaaaug uggagaaauu aagaaaugcu ccaaaugaag agaauaguaa aaagguagaa      240

gauaguaaaa augauaaggu agaacaugug aaaaauauag aagaggcaaa gguugagcaa      300

guugcacccg aaguaaaauc uaaaucaacu uuaagaagug cuucuauagc gaauacuaau      360

ucugagaaau augauuuuga guauuuaaau gguuugagcu auacugaacu uacaaauuua      420

auuaaaaaua uaaaguggaa ucaaauuaau gguuuauuua auuauaguac agguucucaa      480

aaguucuuug gagauaaaaa ucguguacaa gcuauaauua augcuuuaca agaaagugga      540

agaacuuaca cugcaaauga uaugaagggu auagaaacuu ucacugaggu uuuaagagcu      600

gguuuuuauu uaggguacua uaaugauggu uuaucuuauu uaaaugauag aaacuuccaa      660

gauaaaugua uaccugcaau gauugcaauu caaaaaaauc cuaacuuuaa gcuaggaacu      720

gcaguucaag augaaguuau aacuucuuua ggaaaacuaa uaggaaaugc uucugcuaau      780

gcugaaguag uuaauaauug uguaccaguu cuaaaacaau uuagagaaaa cuuaaaucaa      840

uaugcuccug auuacguuaa aggaacagcu guaaaugaau uaauuaaagg uauugaguuc      900

gauuuuucug gugcugcaua ugaaaaagau guuaagacaa ugccuuggua uggaaaaauu      960

gauccauuua uaaaugaacu uaaggccuua ggucuauaug gaaauauaac aagugcaacu     1020

gagugggcau cugauguugg aauauacuau uuaaguaaau ucggucuuua cucaacuaac     1080

cgaaaugaca uaguacaguc acuugaaaag gcuguagaua uguauaagua ugguaaaaua     1140

gccuuuguag caauggagag aauaacuugg gauuaugaug ggauugguuc uaaugguaaa     1200

aagguggauc acgauaaguu cuuagaugau gcugaaaaac auuaucugcc aaagacauau     1260

acuuuugaua auggaaccuu uauuauaaga gcaggggaua agguauccga agaaaaaaua     1320

aaaaggcuau auugggcauc aagagaagug aagucucaau uccauagagu aguuggcaau     1380

gauaaagcau uagagguggg aaaugccgau gauguuuuaa cuaugaaaau auuuaauagc     1440

ccagaagaau auaaauuuaa uaccaauaua aaugguguaa gcacugauaa ugguggucua     1500

uauauagaac caagagggac uuucuacacu uaugagagaa caccucaaca aaguauauuu     1560

agucuugaag aauuguuuag acaugaauau acucacuauu uacaagcgag auaucuugua     1620

gaugguuuau gggggcaagg uccauuuuau gaaaaaaaua gauuaacuug guuugaugaa     1680

gguacagcug aguucuuugc aggaucuacc cguacaucug guguuuuacc aagaaaauca     1740

auauuaggau auuuggcuaa ggauaaagua gaucauagau acucauuaaa gaagacucuu     1800

aauucagggu augaugacag ugauuggaug uucuauaauu auggauuugc aguugcacau     1860

uaccuauaug aaaaagauau gccuacauuu auuaagauga auaaagcuau auugaauaca     1920

gaugugaaau cuuaugauga aauaauaaaa aaauuaagug augaugcaaa uaaaaauaca     1980

gaauaucaaa accauauuca agaguuagca gauaaauauc aaggagcagg cauaccucua     2040

guaucagaug auuacuuaaa agaucaugga uauaagaaag caucugaagu auauucugaa     2100

auuucaaaag cugcuucucu uacaaacaca aguguaacag cagaaaaauc ucaauauuuu     2160

aacacauuca cuuuaagagg aacuuauaca ggugaaacuu cuaaagguga auuuaaagau     2220

ugggaugaaa ugaguaaaaa auuagaugga acuuuggagu cccuugcuaa aaauucuugg     2280

aguggauaca aaacuuuaac agcauacuuu acgaauuaua gaguuacaag cgauaauaaa     2340

guucaauaug auguaguuuu ccaugggguu uuaacagaua augcggauau uaguaacaau     2400

aaggcuccaa uagcaaaggu aacuggacca agcacuggug cuguaggaag aaauauugaa     2460

uuuaguggaa aagauaguaa agaugaagau gguaaaauag uaucauauga uugggauuuu     2520

ggcgauggug caacaaguag aggcaaaaau ucaguacaug cuuacaaaaa agcaggaaca     2580

uauaauguua cauuaaaagu aacugacgau aagggugcaa cagcuacaga gagcuuuacu     2640

auagaaauaa agaacgaaga uacaacaaca ccuauaacua aagaaaugga accuaaugau     2700

gauauaaaag aggcuaaugg uccaauaguu gaagguguua cuguaaaagg ugauuuaaau     2760

gguucugaug augcugauac cuucuauuuu gauguaaaag aagaugguga uguuacaauu     2820

gaacuuccuu auucaggguc aucuaauuuc acaugguuag uuuauaaaga gggagacgau     2880

caaaaccaua uugcaagugg uauagauaag aauaacucaa aaguuggaac auuuaaaucu     2940

acaaaaggaa gacauuaugu guuuauauau aaacacgauu cugcuucaaa uauauccuau     3000

ucuuuaaaca uaaaaggauu agguaacgag aaauugaagg aaaaagaaaa uaaugauucu     3060

ucugauaaag cuacaguuau accaaauuuc aauaccacua ugcaagguuc acuuuuaggu     3120

gaugauucaa gagauuauua uucuuuugag guuaaggaag aaggcgaagu uaauauagaa     3180

cuagauaaaa aggaugaauu ugguguaaca uggacacuac auccagaguc aaauauuaau     3240

gacagaauaa cuuacggaca aguugauggu aauaagguau cuaauaaagu uaaauuaaga     3300

ccaggaaaau auuaucuacu uguuuauaaa uacucaggau caggaaacua ugaguuaagg     3360

guaaauaaau aaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  1382
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (wt)

<400>  1382
gggagaaagc uuaccaugaa guggguaacc uuuauuuccc uucuuuuucu cuuuagcucg       60

gcuuauucca uagcgaauac uaauucugag aaauaugauu uugaguauuu aaaugguuug      120

agcuauacug aacuuacaaa uuuaauuaaa aauauaaagu ggaaucaaau uaaugguuua      180

uuuaauuaua guacagguuc ucaaaaguuc uuuggagaua aaaaucgugu acaagcuaua      240

auuaaugcuu uacaagaaag uggaagaacu uacacugcaa augauaugaa ggguauagaa      300

acuuucacug agguuuuaag agcugguuuu uauuuagggu acuauaauga ugguuuaucu      360

uauuuaaaug auagaaacuu ccaagauaaa uguauaccug caaugauugc aauucaaaaa      420

aauccuaacu uuaagcuagg aacugcaguu caagaugaag uuauaacuuc uuuaggaaaa      480

cuaauaggaa augcuucugc uaaugcugaa guaguuaaua auuguguacc aguucuaaaa      540

caauuuagag aaaacuuaaa ucaauaugcu ccugauuacg uuaaaggaac agcuguaaau      600

gaauuaauua aagguauuga auucgauuuu ucuggugcug cauaugaaaa agauguuaag      660

acaaugccuu gguauggaaa aauugaucca uuuauaaaug aacuuaaggc cuuaggucua      720

uauggaaaua uaacaagugc aacugagugg gcaucugaug uuggaauaua cuauuuaagu      780

aaauucgguc uuuacucaac uaaccgaaau gacauaguac agucacuuga aaaggcugua      840

gauauguaua aguaugguaa aauagccuuu guagcaaugg agagaauaac uugggauuau      900

gaugggauug guucuaaugg uaaaaaggug gaucacgaua aguucuuaga ugaugcugaa      960

aaacauuauc ugccaaagac auauacuuuu gauaauggaa ccuuuauuau aagagcaggg     1020

gauaagguau ccgaagaaaa aauaaaaagg cuauauuggg caucaagaga agugaagucu     1080

caauuccaua gaguaguugg caaugauaaa gcuuuagagg ugggaaaugc cgaugauguu     1140

uuaacuauga aaauauuuaa uagcccagaa gaauauaaau uuaauaccaa uauaaauggu     1200

guaagcacug auaauggugg ucuauauaua gaaccaagag ggacuuucua cacuuaugag     1260

agaacaccuc aacaaaguau auuuagucuu gaagaauugu uuagacauga auauacucac     1320

uauuuacaag cgagauaucu uguagauggu uuaugggggc aagguccauu uuaugaaaaa     1380

aauagauuaa cuugguuuga ugaagguaca gcugaauucu uugcaggauc uacccguaca     1440

ucugguguuu uaccaagaaa aucaauauua ggauauuugg cuaaggauaa aguagaucau     1500

agauacucau uaaagaagac ucuuaauuca ggguaugaug acagugauug gauguucuau     1560

aauuauggau uugcaguugc acauuaccua uaugaaaaag auaugccuac auuuauuaag     1620

augaauaaag cuauauugaa uacagaugug aaaucuuaug augaaauaau aaaaaaauua     1680

agugaugaug caaauaaaaa uacagaauau caaaaccaua uucaagaguu agcagauaaa     1740

uaucaaggag caggcauacc ucuaguauca gaugauuacu uaaaagauca uggauauaag     1800

aaagcaucug aaguauauuc ugaaauuuca aaagcugcuu cucuuacaaa cacuagugua     1860

acagcagaaa aaucucaaua uuuuaacaca uucacuuuaa gaggaacuua uacaggugaa     1920

acuucuaaag gugaauuuaa agauugggau gaaaugagua aaaaauuaga uggaacuuug     1980

gagucccuug cuaaaaauuc uuggagugga uacaaaacuu uaacagcaua cuuuacgaau     2040

uauagaguua caagcgauaa uaaaguucaa uaugauguag uuuuccaugg gguuuuaaca     2100

gauaaugcgg auauuaguaa caauaaggcu ccaauagcaa agguaacugg accaagcacu     2160

ggugcuguag gaagaaauau ugaauuuagu ggaaaagaua guaaagauga agaugguaaa     2220

auaguaucau augauuggga uuuuggcgau ggugcaacua guagaggcaa aaauucagua     2280

caugcuuaca aaaaagcagg aacauauaau guuacauuaa aaguaacuga cgauaagggu     2340

gcaacagcua cagaaagcuu uacuauagaa auaaagaacg aagauacaac aacaccuaua     2400

acuaaagaaa uggaaccuaa ugaugauaua aaagaggcua augguccaau aguugaaggu     2460

guuacuguaa aaggugauuu aaaugguucu gaugaugcug auaccuucua uuuugaugua     2520

aaagaagaug gugauguuac aauugaacuu ccuuauucag ggucaucuaa uuucacaugg     2580

uuaguuuaua aagagggaga cgaucaaaac cauauugcaa gugguauaga uaagaauaac     2640

ucaaaaguug gaacauuuaa aucuacaaaa ggaagacauu auguguuuau auauaaacac     2700

gauucugcuu caaauauauc cuauucuuua aacauaaaag gauuagguaa cgagaaauug     2760

aaggaaaaag aaaauaauga uucuucugau aaagcuacag uuauaccaaa uuucaauacc     2820

acuaugcaag guucacuuuu aggugaugau ucaagagauu auuauucuuu ugagguuaag     2880

gaagaaggcg aaguuaauau agaacuagau aaaaaggaug aauuuggugu aacauggaca     2940

cuacauccag agucaaauau uaaugacaga auaacuuacg gacaaguuga ugguaauaag     3000

guaucuaaua aaguuaaauu aagaccagga aaauauuauc uacuuguuua uaaauacuca     3060

ggaucaggaa acuaugaguu aaggguaaau aaauaaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  1383
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (wt)

<400>  1383
gggagaaagc uuaccaugaa guggguaacc uuuauuuccc uucuuuuucu cuuuagcucg       60

gcuuauucca uagcgaauac uaauucugag aaauaugauu uugaguauuu aaaugguuug      120

agcuauacug aacuuacaaa uuuaauuaaa aauauaaagu ggaaucaaau uaaugguuua      180

uuuaauuaua guacagguuc ucaaaaguuc uuuggagaua aaaaucgugu acaagcuaua      240

auuaaugcuu uacaagaaag uggaagaacu uacacugcaa augauaugaa ggguauagaa      300

acuuucacug agguuuuaag agcugguuuu uauuuagggu acuauaauga ugguuuaucu      360

uauuuaaaug auagaaacuu ccaagauaaa uguauaccug caaugauugc aauucaaaaa      420

aauccuaacu uuaagcuagg aacugcaguu caagaugaag uuauaacuuc uuuaggaaaa      480

cuaauaggaa augcuucugc uaaugcugaa guaguuaaua auuguguacc aguucuaaaa      540

caauuuagag aaaacuuaaa ucaauaugcu ccugauuacg uuaaaggaac agcuguaaau      600

gaauuaauua aagguauuga guucgauuuu ucuggugcug cauaugaaaa agauguuaag      660

acaaugccuu gguauggaaa aauugaucca uuuauaaaug aacuuaaggc cuuaggucua      720

uauggaaaua uaacaagugc aacugagugg gcaucugaug uuggaauaua cuauuuaagu      780

aaauucgguc uuuacucaac uaaccgaaau gacauaguac agucacuuga aaaggcugua      840

gauauguaua aguaugguaa aauagccuuu guagcaaugg agagaauaac uugggauuau      900

gaugggauug guucuaaugg uaaaaaggug gaucacgaua aguucuuaga ugaugcugaa      960

aaacauuauc ugccaaagac auauacuuuu gauaauggaa ccuuuauuau aagagcaggg     1020

gauaagguau ccgaagaaaa aauaaaaagg cuauauuggg caucaagaga agugaagucu     1080

caauuccaua gaguaguugg caaugauaaa gcauuagagg ugggaaaugc cgaugauguu     1140

uuaacuauga aaauauuuaa uagcccagaa gaauauaaau uuaauaccaa uauaaauggu     1200

guaagcacug auaauggugg ucuauauaua gaaccaagag ggacuuucua cacuuaugag     1260

agaacaccuc aacaaaguau auuuagucuu gaagaauugu uuagacauga auauacucac     1320

uauuuacaag cgagauaucu uguagauggu uuaugggggc aagguccauu uuaugaaaaa     1380

aauagauuaa cuugguuuga ugaagguaca gcugaguucu uugcaggauc uacccguaca     1440

ucugguguuu uaccaagaaa aucaauauua ggauauuugg cuaaggauaa aguagaucau     1500

agauacucau uaaagaagac ucuuaauuca ggguaugaug acagugauug gauguucuau     1560

aauuauggau uugcaguugc acauuaccua uaugaaaaag auaugccuac auuuauuaag     1620

augaauaaag cuauauugaa uacagaugug aaaucuuaug augaaauaau aaaaaaauua     1680

agugaugaug caaauaaaaa uacagaauau caaaaccaua uucaagaguu agcagauaaa     1740

uaucaaggag caggcauacc ucuaguauca gaugauuacu uaaaagauca uggauauaag     1800

aaagcaucug aaguauauuc ugaaauuuca aaagcugcuu cucuuacaaa cacaagugua     1860

acagcagaaa aaucucaaua uuuuaacaca uucacuuuaa gaggaacuua uacaggugaa     1920

acuucuaaag gugaauuuaa agauugggau gaaaugagua aaaaauuaga uggaacuuug     1980

gagucccuug cuaaaaauuc uuggagugga uacaaaacuu uaacagcaua cuuuacgaau     2040

uauagaguua caagcgauaa uaaaguucaa uaugauguag uuuuccaugg gguuuuaaca     2100

gauaaugcgg auauuaguaa caauaaggcu ccaauagcaa agguaacugg accaagcacu     2160

ggugcuguag gaagaaauau ugaauuuagu ggaaaagaua guaaagauga agaugguaaa     2220

auaguaucau augauuggga uuuuggcgau ggugcaacaa guagaggcaa aaauucagua     2280

caugcuuaca aaaaagcagg aacauauaau guuacauuaa aaguaacuga cgauaagggu     2340

gcaacagcua cagagagcuu uacuauagaa auaaagaacg aagauacaac aacaccuaua     2400

acuaaagaaa uggaaccuaa ugaugauaua aaagaggcua augguccaau aguugaaggu     2460

guuacuguaa aaggugauuu aaaugguucu gaugaugcug auaccuucua uuuugaugua     2520

aaagaagaug gugauguuac aauugaacuu ccuuauucag ggucaucuaa uuucacaugg     2580

uuaguuuaua aagagggaga cgaucaaaac cauauugcaa gugguauaga uaagaauaac     2640

ucaaaaguug gaacauuuaa aucuacaaaa ggaagacauu auguguuuau auauaaacac     2700

gauucugcuu caaauauauc cuauucuuua aacauaaaag gauuagguaa cgagaaauug     2760

aaggaaaaag aaaauaauga uucuucugau aaagcuacag uuauaccaaa uuucaauacc     2820

acuaugcaag guucacuuuu aggugaugau ucaagagauu auuauucuuu ugagguuaag     2880

gaagaaggcg aaguuaauau agaacuagau aaaaaggaug aauuuggugu aacauggaca     2940

cuacauccag agucaaauau uaaugacaga auaacuuacg gacaaguuga ugguaauaag     3000

guaucuaaua aaguuaaauu aagaccagga aaauauuauc uacuuguuua uaaauacuca     3060

ggaucaggaa acuaugaguu aaggguaaau aaauaaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  1384
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (wt)

<400>  1384
gggagaaagc uuaccaugaa guggguaacc uuuauuuccc uucuuuuucu cuuuagcucg       60

gcuuauucca ugaaaaaaaa uauuuuaaag auucuuaugg auaguuauuc uaaagaaucu      120

aaaauucaaa cuguacguag gguuacgagu guaucacuuu uagcgguaua ucuuacuaug      180

aauacuucaa guuuaguuuu agcaaaacca auagaaaaua cuaaugauac uaguauaaaa      240

aauguggaga aauuaagaaa ugcuccaaau gaagagaaua guaaaaaggu agaagauagu      300

aaaaaugaua agguagaaca ugugaaaaau auagaagagg caaagguuga gcaaguugca      360

cccgaaguaa aaucuaaauc aacuuuaaga agugcuucua gaaggcggcg caagagaaua      420

gcgaauacua auucugagaa auaugauuuu gaguauuuaa augguuugag cuauacugaa      480

cuuacaaauu uaauuaaaaa uauaaagugg aaucaaauua augguuuauu uaauuauagu      540

acagguucuc aaaaguucuu uggagauaaa aaucguguac aagcuauaau uaaugcuuua      600

caagaaagug gaagaacuua cacugcaaau gauaugaagg guauagaaac uuucacugag      660

guuuuaagag cugguuuuua uuuaggguac uauaaugaug guuuaucuua uuuaaaugau      720

agaaacuucc aagauaaaug uauaccugca augauugcaa uucaaaaaaa uccuaacuuu      780

aagcuaggaa cugcaguuca agaugaaguu auaacuucuu uaggaaaacu aauaggaaau      840

gcuucugcua augcugaagu aguuaauaau uguguaccag uucuaaaaca auuuagagaa      900

aacuuaaauc aauaugcucc ugauuacguu aaaggaacag cuguaaauga auuaauuaaa      960

gguauugaau ucgauuuuuc uggugcugca uaugaaaaag auguuaagac aaugccuugg     1020

uauggaaaaa uugauccauu uauaaaugaa cuuaaggccu uaggucuaua uggaaauaua     1080

acaagugcaa cugagugggc aucugauguu ggaauauacu auuuaaguaa auucggucuu     1140

uacucaacua accgaaauga cauaguacag ucacuugaaa aggcuguaga uauguauaag     1200

uaugguaaaa uagccuuugu agcaauggag agaauaacuu gggauuauga ugggauuggu     1260

ucuaauggua aaaaggugga ucacgauaag uucuuagaug augcugaaaa acauuaucug     1320

ccaaagacau auacuuuuga uaauggaacc uuuauuauaa gagcagggga uaagguaucc     1380

gaagaaaaaa uaaaaaggcu auauugggca ucaagagaag ugaagucuca auuccauaga     1440

guaguuggca augauaaagc uuuagaggug ggaaaugccg augauguuuu aacuaugaaa     1500

auauuuaaua gcccagaaga auauaaauuu aauaccaaua uaaauggugu aagcacugau     1560

aauggugguc uauauauaga accaagaggg acuuucuaca cuuaugagag aacaccucaa     1620

caaaguauau uuagucuuga agaauuguuu agacaugaau auacucacua uuuacaagcg     1680

agauaucuug uagaugguuu augggggcaa gguccauuuu augaaaaaaa uagauuaacu     1740

ugguuugaug aagguacagc ugaauucuuu gcaggaucua cccguacauc ugguguuuua     1800

ccaagaaaau caauauuagg auauuuggcu aaggauaaag uagaucauag auacucauua     1860

aagaagacuc uuaauucagg guaugaugac agugauugga uguucuauaa uuauggauuu     1920

gcaguugcac auuaccuaua ugaaaaagau augccuacau uuauuaagau gaauaaagcu     1980

auauugaaua cagaugugaa aucuuaugau gaaauaauaa aaaaauuaag ugaugaugca     2040

aauaaaaaua cagaauauca aaaccauauu caagaguuag cagauaaaua ucaaggagca     2100

ggcauaccuc uaguaucaga ugauuacuua aaagaucaug gauauaagaa agcaucugaa     2160

guauauucug aaauuucaaa agcugcuucu cuuacaaaca cuaguguaac agcagaaaaa     2220

ucucaauauu uuaacacauu cacuuuaaga ggaacuuaua caggugaaac uucuaaaggu     2280

gaauuuaaag auugggauga aaugaguaaa aaauuagaug gaacuuugga gucccuugcu     2340

aaaaauucuu ggaguggaua caaaacuuua acagcauacu uuacgaauua uagaguuaca     2400

agcgauaaua aaguucaaua ugauguaguu uuccaugggg uuuuaacaga uaaugcggau     2460

auuaguaaca auaaggcucc aauagcaaag guaacuggac caagcacugg ugcuguagga     2520

agaaauauug aauuuagugg aaaagauagu aaagaugaag augguaaaau aguaucauau     2580

gauugggauu uuggcgaugg ugcaacuagu agaggcaaaa auucaguaca ugcuuacaaa     2640

aaagcaggaa cauauaaugu uacauuaaaa guaacugacg auaagggugc aacagcuaca     2700

gaaagcuuua cuauagaaau aaagaacgaa gauacaacaa caccuauaac uaaagaaaug     2760

gaaccuaaug augauauaaa agaggcuaau gguccaauag uugaaggugu uacuguaaaa     2820

ggugauuuaa augguucuga ugaugcugau accuucuauu uugauguaaa agaagauggu     2880

gauguuacaa uugaacuucc uuauucaggg ucaucuaauu ucacaugguu aguuuauaaa     2940

gagggagacg aucaaaacca uauugcaagu gguauagaua agaauaacuc aaaaguugga     3000

acauuuaaau cuacaaaagg aagacauuau guguuuauau auaaacacga uucugcuuca     3060

aauauauccu auucuuuaaa cauaaaagga uuagguaacg agaaauugaa ggaaaaagaa     3120

aauaaugauu cuucugauaa agcuacaguu auaccaaauu ucaauaccac uaugcaaggu     3180

ucacuuuuag gugaugauuc aagagauuau uauucuuuug agguuaagga agaaggcgaa     3240

guuaauauag aacuagauaa aaaggaugaa uuugguguaa cauggacacu acauccagag     3300

ucaaauauua augacagaau aacuuacgga caaguugaug guaauaaggu aucuaauaaa     3360

guuaaauuaa gaccaggaaa auauuaucua cuuguuuaua aauacucagg aucaggaaac     3420

uaugaguuaa ggguaaauaa auaaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  1385
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (wt)

<400>  1385
gggagaaagc uuaccaugaa guggguaacc uuuauuuccc uucuuuuucu cuuuagcucg       60

gcuuauucca ugaaaaaaaa uauuuuaaag auucuuaugg auaguuauuc uaaagaaucu      120

aaaauucaaa cuguacguag gguuacgagu guaucacuuu uagcgguaua ucuuacuaug      180

aauacuucaa guuuaguuuu agcaaaacca auagaaaaua cuaaugauac aaguauaaaa      240

aauguggaga aauuaagaaa ugcuccaaau gaagagaaua guaaaaaggu agaagauagu      300

aaaaaugaua agguagaaca ugugaaaaau auagaagagg caaagguuga gcaaguugca      360

cccgaaguaa aaucuaaauc aacuuuaaga agugcuucua gaaggcggcg caagagaaua      420

gcgaauacua auucugagaa auaugauuuu gaguauuuaa augguuugag cuauacugaa      480

cuuacaaauu uaauuaaaaa uauaaagugg aaucaaauua augguuuauu uaauuauagu      540

acagguucuc aaaaguucuu uggagauaaa aaucguguac aagcuauaau uaaugcuuua      600

caagaaagug gaagaacuua cacugcaaau gauaugaagg guauagaaac uuucacugag      660

guuuuaagag cugguuuuua uuuaggguac uauaaugaug guuuaucuua uuuaaaugau      720

agaaacuucc aagauaaaug uauaccugca augauugcaa uucaaaaaaa uccuaacuuu      780

aagcuaggaa cugcaguuca agaugaaguu auaacuucuu uaggaaaacu aauaggaaau      840

gcuucugcua augcugaagu aguuaauaau uguguaccag uucuaaaaca auuuagagaa      900

aacuuaaauc aauaugcucc ugauuacguu aaaggaacag cuguaaauga auuaauuaaa      960

gguauugagu ucgauuuuuc uggugcugca uaugaaaaag auguuaagac aaugccuugg     1020

uauggaaaaa uugauccauu uauaaaugaa cuuaaggccu uaggucuaua uggaaauaua     1080

acaagugcaa cugagugggc aucugauguu ggaauauacu auuuaaguaa auucggucuu     1140

uacucaacua accgaaauga cauaguacag ucacuugaaa aggcuguaga uauguauaag     1200

uaugguaaaa uagccuuugu agcaauggag agaauaacuu gggauuauga ugggauuggu     1260

ucuaauggua aaaaggugga ucacgauaag uucuuagaug augcugaaaa acauuaucug     1320

ccaaagacau auacuuuuga uaauggaacc uuuauuauaa gagcagggga uaagguaucc     1380

gaagaaaaaa uaaaaaggcu auauugggca ucaagagaag ugaagucuca auuccauaga     1440

guaguuggca augauaaagc auuagaggug ggaaaugccg augauguuuu aacuaugaaa     1500

auauuuaaua gcccagaaga auauaaauuu aauaccaaua uaaauggugu aagcacugau     1560

aauggugguc uauauauaga accaagaggg acuuucuaca cuuaugagag aacaccucaa     1620

caaaguauau uuagucuuga agaauuguuu agacaugaau auacucacua uuuacaagcg     1680

agauaucuug uagaugguuu augggggcaa gguccauuuu augaaaaaaa uagauuaacu     1740

ugguuugaug aagguacagc ugaguucuuu gcaggaucua cccguacauc ugguguuuua     1800

ccaagaaaau caauauuagg auauuuggcu aaggauaaag uagaucauag auacucauua     1860

aagaagacuc uuaauucagg guaugaugac agugauugga uguucuauaa uuauggauuu     1920

gcaguugcac auuaccuaua ugaaaaagau augccuacau uuauuaagau gaauaaagcu     1980

auauugaaua cagaugugaa aucuuaugau gaaauaauaa aaaaauuaag ugaugaugca     2040

aauaaaaaua cagaauauca aaaccauauu caagaguuag cagauaaaua ucaaggagca     2100

ggcauaccuc uaguaucaga ugauuacuua aaagaucaug gauauaagaa agcaucugaa     2160

guauauucug aaauuucaaa agcugcuucu cuuacaaaca caaguguaac agcagaaaaa     2220

ucucaauauu uuaacacauu cacuuuaaga ggaacuuaua caggugaaac uucuaaaggu     2280

gaauuuaaag auugggauga aaugaguaaa aaauuagaug gaacuuugga gucccuugcu     2340

aaaaauucuu ggaguggaua caaaacuuua acagcauacu uuacgaauua uagaguuaca     2400

agcgauaaua aaguucaaua ugauguaguu uuccaugggg uuuuaacaga uaaugcggau     2460

auuaguaaca auaaggcucc aauagcaaag guaacuggac caagcacugg ugcuguagga     2520

agaaauauug aauuuagugg aaaagauagu aaagaugaag augguaaaau aguaucauau     2580

gauugggauu uuggcgaugg ugcaacaagu agaggcaaaa auucaguaca ugcuuacaaa     2640

aaagcaggaa cauauaaugu uacauuaaaa guaacugacg auaagggugc aacagcuaca     2700

gagagcuuua cuauagaaau aaagaacgaa gauacaacaa caccuauaac uaaagaaaug     2760

gaaccuaaug augauauaaa agaggcuaau gguccaauag uugaaggugu uacuguaaaa     2820

ggugauuuaa augguucuga ugaugcugau accuucuauu uugauguaaa agaagauggu     2880

gauguuacaa uugaacuucc uuauucaggg ucaucuaauu ucacaugguu aguuuauaaa     2940

gagggagacg aucaaaacca uauugcaagu gguauagaua agaauaacuc aaaaguugga     3000

acauuuaaau cuacaaaagg aagacauuau guguuuauau auaaacacga uucugcuuca     3060

aauauauccu auucuuuaaa cauaaaagga uuagguaacg agaaauugaa ggaaaaagaa     3120

aauaaugauu cuucugauaa agcuacaguu auaccaaauu ucaauaccac uaugcaaggu     3180

ucacuuuuag gugaugauuc aagagauuau uauucuuuug agguuaagga agaaggcgaa     3240

guuaauauag aacuagauaa aaaggaugaa uuugguguaa cauggacacu acauccagag     3300

ucaaauauua augacagaau aacuuacgga caaguugaug guaauaaggu aucuaauaaa     3360

guuaaauuaa gaccaggaaa auauuaucua cuuguuuaua aauacucagg aucaggaaac     3420

uaugaguuaa ggguaaauaa auaaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  1386
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  1386
gggagaaagc uuaccaugaa uuuuuuaaaa auuauuuuaa auagggggaa gacuaugaaa       60

aggaaauguu uaucuaaaag gcuuauguua gcuauaacaa uggcuacaau auuuacagug      120

aacaguacau uaccaauuua ugcagcugua gauaaaaaua augcaacagc agcuguacaa      180

aaugaaagua agagguauac aguaucauau uuaaagacuu uaaauuauua ugacuuagua      240

gauuugcuug uuaagacuga aauugagaau uuaccagacc uuuuucagua uaguucagau      300

gcaaaagagu ucuauggaaa uaaaacucgu augagcuuua ucauggauga aauugguaga      360

agggcaccuc aguauacaga gauagaucau aaagguauuc cuacuuuagu agaaguugua      420

agagcuggau uuuacuuagg auuccauaac aaggaauuga augaaauaaa caagaggucu      480

uuuaaagaaa ggguaauacc uucuauauua gcaauucaaa aaaauccuaa uuuuaaacua      540

gguacugaag uucaagauaa aauaguaucu gcaacaggac uuuuagcugg uaaugaaaca      600

gcgccuccag aaguuguaaa uaauuuuaca ccaauacuuc aagacuguau aaagaauaua      660

gacagauacg cucuugauga uuuaaaguca aaagcauuau uuaauguuuu agcugcaccu      720

accuaugaua uaacugagua uuuaagagcu acuaaagaaa aaccagaaaa cacuccuugg      780

uaugguaaaa uagauggguu uauaaaugaa cuuaaaaagu uagcucuuua uggaaaaaua      840

aaugauaaua acucuuggau aauagauaac gguauauauc auauagcacc uuuagggaag      900

uuacauagca auaauaaaau aggaauagaa acuuuaacag agguuaugaa aguuuauccu      960

uauuuaagua ugcaacauuu acaaucagca gaucaaauua agcgucauua ugauucaaaa     1020

gaugcugaag gaaacaaaau accuuuagau aaguuuaaaa aggaaggaaa agaaaaauac     1080

uguccaaaaa cuuauacauu ugaugaugga aaaguaauaa uaaaagcugg ugcuagagua     1140

gaagaagaaa aaguuaaaag acuauacugg gcaucaaagg aaguuaacuc ucaauucuuu     1200

agaguauacg gaauagacaa accauuagaa gaagguaauc cagaugauau auuaacaaug     1260

guuaucuaca acagucccga agaauauaaa cucaauagug uucuauacgg auaugauacu     1320

aauaauggug guauguauau agagccagaa ggaacuuucu ucaccuauga aagagaagcu     1380

caagaaagca cauacacauu agaagaauua uuuagacaug aauauacaca uuauuugcaa     1440

ggaagauaug caguuccagg acaaugggga agaacaaaac uuuaugacaa ugauagauua     1500

acuugguaug aagaaggugg agcagaauua uuugcagguu cuacuagaac uucuggaaua     1560

uuaccaagaa agaguauagu aucaaauauu cauaauacaa caagaaauaa uagauauaag     1620

cuuucagaca cuguacauuc uaaauauggu gcuaguuuug aauucuauaa uuaugcaugu     1680

auguuuaugg auuauaugua uaauaaagau auggguauau uaaauaaacu aaaugaucuu     1740

gcaaaaaaua augauguuga uggauaugau aauuauauua gagauuuaag uucuaauuau     1800

gcuuuaaaug auaaauauca agaucauaug caggagcgca uagauaauua ugaaaauuua     1860

acagugccuu uuguagcuga ugauuauuua guaaggcaug cuuauaagaa cccuaaugaa     1920

auuuauucug aaauaucuga aguagcaaaa uuaaaggaug cuaagaguga aguuaagaaa     1980

ucacaauauu uuaguaccuu uacuuugaga gguaguuaca cagguggagc aucuaagggg     2040

aaauuagaag aucaaaaagc aaugaauaag uuuauagaug auucacuuaa gaaauuagau     2100

acguauucuu ggagugggua uaaaacuuua acugcuuauu ucacuaauua uaaaguugac     2160

ucuucaaaua gaguuacuua ugauguagua uuccacggau auuuaccaaa cgaaggugau     2220

uccaaaaauu cauuaccuua uggcaagauc aauggaacuu acaagggaac agagaaagaa     2280

aaaaucaaau ucucuaguga aggcucuuuc gauccagaug guaaaauagu uucuuaugaa     2340

ugggauuucg gagaugguaa uaagaguaau gaggaaaauc cagagcauuc auaugacaag     2400

guaggaacuu auacagugaa auuaaaaguu acugaugaca agggagaauc uucaguaucu     2460

acuacuacug cagaaauaaa ggaucuuuca gaaaauaaac uuccaguuau auauaugcau     2520

guaccuaaau ccggagccuu aaaucaaaaa guuguuuucu auggaaaagg aacauaugac     2580

ccagauggau cuaucgcagg auaucaaugg gacuuuggug auggaaguga uuuuagcagu     2640

gaacaaaacc caagccaugu auauacuaaa aaaggugaau auacuguaac auuaagagua     2700

auggauagua guggacaaau gagugaaaaa acuaugaaga uuaagauuac agauccggua     2760

uauccaauag gcacugaaaa agaaccaaau aacaguaaag aaacugcaag ugguccaaua     2820

guaccaggua uaccuguuag uggaaccaua gaaaauacaa gugaucaaga uuauuucuau     2880

uuugauguua uaacaccagg agaaguaaaa auagauauaa auaaauuagg guacggagga     2940

gcuacuuggg uaguauauga ugaaaauaau aaugcaguau cuuaugccac ugaugauggg     3000

caaaauuuaa guggaaaguu uaaggcagau aaaccaggua gauauuacau ccaucuuuac     3060

auguuuaaug guaguuauau gccauauaga auuaauauag aagguucagu aggaagauaa     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  1387
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  1387
gggagaaagc uuaccaugaa uuuuuuaaaa auuauuuuaa auagggggaa gacuaugaaa       60

aggaaauguu uaucuaaaag gcuuauguua gcuauaacaa uggcuacaau auuuacagug      120

aacaguacau uaccaauuua ugcagcugua gauaaaaaua augcaacagc agcuguacaa      180

aaugaaagua agagguauac aguaucauau uuaaagacuu uaaauuauua ugacuuagua      240

gauuugcuug uuaagacuga aauugagaau uuaccagacc uuuuucagua uaguucagau      300

gcaaaagagu ucuauggaaa uaaaacucgu augagcuuua ucauggauga aauugguaga      360

agggcaccuc aguauacaga gauagaucau aaagguauuc cuacuuuagu agaaguugua      420

agagcuggau uuuacuuagg auuccauaac aaggaauuga augaaauaaa caagaggucu      480

uuuaaagaaa ggguaauacc uucuauauua gcaauucaaa aaaauccuaa uuuuaaacua      540

gguacugaag uucaagauaa aauaguaucu gcaacaggac uuuuagcugg uaaugaaaca      600

gcgccuccag aaguuguaaa uaauuuuaca ccaauacuuc aagacuguau aaagaauaua      660

gacagauacg cucuugauga uuuaaaguca aaagcauuau uuaauguuuu agcugcaccu      720

accuaugaua uaacugagua uuuaagagcu acuaaagaaa aaccagaaaa cacuccuugg      780

uaugguaaaa uagauggguu uauaaaugaa cuuaaaaagu uagcucuuua uggaaaaaua      840

aaugauaaua acucuuggau aauagauaac gguauauauc auauagcacc uuuagggaag      900

uuacauagca auaauaaaau aggaauagaa acuuuaacag agguuaugaa aguuuauccu      960

uauuuaagua ugcaacauuu acaaucagca gaucaaauua agcgucauua ugauucaaaa     1020

gaugcugaag gaaacaaaau accuuuagau aaguuuaaaa aggaaggaaa agaaaaauac     1080

uguccaaaaa cuuauacauu ugaugaugga aaaguaauaa uaaaagcugg ugcuagagua     1140

gaagaagaaa aaguuaaaag acuauacugg gcaucaaagg aaguuaacuc ucaauucuuu     1200

agaguauacg gaauagacaa accauuagaa gaagguaauc cagaugauau auuaacaaug     1260

guuaucuaca acagucccga agaauauaaa cucaauagug uucuauacgg auaugauacu     1320

aauaauggug guauguauau agagccagaa ggaacuuucu ucaccuauga aagagaagcu     1380

caagaaagca cauacacauu agaagaauua uuuagacaug aauauacaca uuauuugcaa     1440

ggaagauaug caguuccagg acaaugggga agaacaaaac uuuaugacaa ugauagauua     1500

acuugguaug aagaaggugg agcagaauua uuugcagguu cuacuagaac uucuggaaua     1560

uuaccaagaa agaguauagu aucaaauauu cauaauacaa caagaaauaa uagauauaag     1620

cugucagaca cuguacauuc uaaauauggu gcuaguuuug aguucuauaa uuaugcaugu     1680

auguuuaugg auuauaugua uaauaaagau auggguauau uaaauaaacu aaaugaucuu     1740

gcaaaaaaua augauguuga uggauaugau aauuauauua gagauuuaag uucuaauuau     1800

gcuuuaaaug auaaauauca agaucauaug caggagcgca uagauaauua ugaaaauuua     1860

acagugccuu uuguagcuga ugauuauuua guaaggcaug cuuauaagaa cccuaaugaa     1920

auuuauucug aaauaucuga aguagcaaaa uuaaaggaug cuaagaguga aguuaagaaa     1980

ucacaauauu uuaguaccuu uacuuugaga gguaguuaca cagguggagc aucuaagggg     2040

aaauuagaag aucaaaaagc aaugaauaag uuuauagaug auucacuuaa gaaauuagau     2100

acguauucuu ggagugggua uaaaacuuua acugcuuauu ucacuaauua uaaaguugac     2160

ucuucaaaua gaguuacuua ugauguagua uuccacggau auuuaccaaa cgaaggugau     2220

uccaaaaauu cauuaccuua uggcaagauc aauggaacuu acaagggaac agagaaagaa     2280

aaaaucaaau ucucuaguga aggcucuuuc gauccagaug guaaaauagu uucuuaugaa     2340

ugggauuucg gagaugguaa uaagaguaau gaggaaaauc cagagcauuc auaugacaag     2400

guaggaacuu auacagugaa auuaaaaguu acugaugaca agggagaauc uucaguaucu     2460

acuacuacug cagaaauaaa ggaucuuuca gaaaauaaac uuccaguuau auauaugcau     2520

guaccuaaau ccggagccuu aaaucaaaaa guuguuuucu auggaaaagg aacauaugac     2580

ccagauggau cuaucgcagg auaucaaugg gacuuuggug auggaaguga uuuuagcagu     2640

gaacaaaacc caagccaugu auauacuaaa aaaggugaau auacuguaac auuaagagua     2700

auggauagua guggacaaau gagugaaaaa acuaugaaga uuaagauuac agauccggua     2760

uauccaauag gcacugaaaa agaaccaaau aacaguaaag aaacugcaag ugguccaaua     2820

guaccaggua uaccuguuag uggaaccaua gaaaauacaa gugaucaaga uuauuucuau     2880

uuugauguua uaacaccagg agaaguaaaa auagauauaa auaaauuagg guacggagga     2940

gcuacuuggg uaguauauga ugaaaauaau aaugcaguau cuuaugccac ugaugauggg     3000

caaaauuuaa guggaaaguu uaaggcagau aaaccaggua gauauuacau ccaucuuuac     3060

auguuuaaug guaguuauau gccauauaga auuaauauag aagguucagu aggaagauaa     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  1388
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  1388
gggagaaagc uuaccaugaa aaggaaaugu uuaucuaaaa ggcuuauguu agcuauaaca       60

auggcuacaa uauuuacagu gaacaguaca uuaccaauuu augcagcugu agauaaaaau      120

aaugcaacag cagcuguaca aaaugaaagu aagagguaua caguaucaua uuuaaagacu      180

uuaaauuauu augacuuagu agauuugcuu guuaagacug aaauugagaa uuuaccagac      240

cuuuuucagu auaguucaga ugcaaaagag uucuauggaa auaaaacucg uaugagcuuu      300

aucauggaug aaauugguag aagggcaccu caguauacag agauagauca uaaagguauu      360

ccuacuuuag uagaaguugu aagagcugga uuuuacuuag gauuccauaa caaggaauug      420

aaugaaauaa acaagagguc uuuuaaagaa aggguaauac cuucuauauu agcaauucaa      480

aaaaauccua auuuuaaacu agguacugaa guucaagaua aaauaguauc ugcaacagga      540

cuuuuagcug guaaugaaac agcgccucca gaaguuguaa auaauuuuac accaauacuu      600

caagacugua uaaagaauau agacagauac gcucuugaug auuuaaaguc aaaagcauua      660

uuuaauguuu uagcugcacc uaccuaugau auaacugagu auuuaagagc uacuaaagaa      720

aaaccagaaa acacuccuug guaugguaaa auagaugggu uuauaaauga acuuaaaaag      780

uuagcucuuu auggaaaaau aaaugauaau aacucuugga uaauagauaa cgguauauau      840

cauauagcac cuuuagggaa guuacauagc aauaauaaaa uaggaauaga aacuuuaaca      900

gagguuauga aaguuuaucc uuauuuaagu augcaacauu uacaaucagc agaucaaauu      960

aagcgucauu augauucaaa agaugcugaa ggaaacaaaa uaccuuuaga uaaguuuaaa     1020

aaggaaggaa aagaaaaaua cuguccaaaa acuuauacau uugaugaugg aaaaguaaua     1080

auaaaagcug gugcuagagu agaagaagaa aaaguuaaaa gacuauacug ggcaucaaag     1140

gaaguuaacu cucaauucuu uagaguauac ggaauagaca aaccauuaga agaagguaau     1200

ccagaugaua uauuaacaau gguuaucuac aacagucccg aagaauauaa acucaauagu     1260

guucuauacg gauaugauac uaauaauggu gguauguaua uagagccaga aggaacuuuc     1320

uucaccuaug aaagagaagc ucaagaaagc acauacacau uagaagaauu auuuagacau     1380

gaauauacac auuauuugca aggaagauau gcaguuccag gacaaugggg aagaacaaaa     1440

cuuuaugaca augauagauu aacuugguau gaagaaggug gagcagaauu auuugcaggu     1500

ucuacuagaa cuucuggaau auuaccaaga aagaguauag uaucaaauau ucauaauaca     1560

acaagaaaua auagauauaa gcuuucagac acuguacauu cuaaauaugg ugcuaguuuu     1620

gaauucuaua auuaugcaug uauguuuaug gauuauaugu auaauaaaga uauggguaua     1680

uuaaauaaac uaaaugaucu ugcaaaaaau aaugauguug auggauauga uaauuauauu     1740

agagauuuaa guucuaauua ugcuuuaaau gauaaauauc aagaucauau gcaggagcgc     1800

auagauaauu augaaaauuu aacagugccu uuuguagcug augauuauuu aguaaggcau     1860

gcuuauaaga acccuaauga aauuuauucu gaaauaucug aaguagcaaa auuaaaggau     1920

gcuaagagug aaguuaagaa aucacaauau uuuaguaccu uuacuuugag agguaguuac     1980

acagguggag caucuaaggg gaaauuagaa gaucaaaaag caaugaauaa guuuauagau     2040

gauucacuua agaaauuaga uacguauucu uggagugggu auaaaacuuu aacugcuuau     2100

uucacuaauu auaaaguuga cucuucaaau agaguuacuu augauguagu auuccacgga     2160

uauuuaccaa acgaagguga uuccaaaaau ucauuaccuu auggcaagau caauggaacu     2220

uacaagggaa cagagaaaga aaaaaucaaa uucucuagug aaggcucuuu cgauccagau     2280

gguaaaauag uuucuuauga augggauuuc ggagauggua auaagaguaa ugaggaaaau     2340

ccagagcauu cauaugacaa gguaggaacu uauacaguga aauuaaaagu uacugaugac     2400

aagggagaau cuucaguauc uacuacuacu gcagaaauaa aggaucuuuc agaaaauaaa     2460

cuuccaguua uauauaugca uguaccuaaa uccggagccu uaaaucaaaa aguuguuuuc     2520

uauggaaaag gaacauauga cccagaugga ucuaucgcag gauaucaaug ggacuuuggu     2580

gauggaagug auuuuagcag ugaacaaaac ccaagccaug uauauacuaa aaaaggugaa     2640

uauacuguaa cauuaagagu aauggauagu aguggacaaa ugagugaaaa aacuaugaag     2700

auuaagauua cagauccggu auauccaaua ggcacugaaa aagaaccaaa uaacaguaaa     2760

gaaacugcaa gugguccaau aguaccaggu auaccuguua guggaaccau agaaaauaca     2820

agugaucaag auuauuucua uuuugauguu auaacaccag gagaaguaaa aauagauaua     2880

aauaaauuag gguacggagg agcuacuugg guaguauaug augaaaauaa uaaugcagua     2940

ucuuaugcca cugaugaugg gcaaaauuua aguggaaagu uuaaggcaga uaaaccaggu     3000

agauauuaca uccaucuuua cauguuuaau gguaguuaua ugccauauag aauuaauaua     3060

gaagguucag uaggaagaua aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  1389
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  1389
gggagaaagc uuaccaugaa aaggaaaugu uuaucuaaaa ggcuuauguu agcuauaaca       60

auggcuacaa uauuuacagu gaacaguaca uuaccaauuu augcagcugu agauaaaaau      120

aaugcaacag cagcuguaca aaaugaaagu aagagguaua caguaucaua uuuaaagacu      180

uuaaauuauu augacuuagu agauuugcuu guuaagacug aaauugagaa uuuaccagac      240

cuuuuucagu auaguucaga ugcaaaagag uucuauggaa auaaaacucg uaugagcuuu      300

aucauggaug aaauugguag aagggcaccu caguauacag agauagauca uaaagguauu      360

ccuacuuuag uagaaguugu aagagcugga uuuuacuuag gauuccauaa caaggaauug      420

aaugaaauaa acaagagguc uuuuaaagaa aggguaauac cuucuauauu agcaauucaa      480

aaaaauccua auuuuaaacu agguacugaa guucaagaua aaauaguauc ugcaacagga      540

cuuuuagcug guaaugaaac agcgccucca gaaguuguaa auaauuuuac accaauacuu      600

caagacugua uaaagaauau agacagauac gcucuugaug auuuaaaguc aaaagcauua      660

uuuaauguuu uagcugcacc uaccuaugau auaacugagu auuuaagagc uacuaaagaa      720

aaaccagaaa acacuccuug guaugguaaa auagaugggu uuauaaauga acuuaaaaag      780

uuagcucuuu auggaaaaau aaaugauaau aacucuugga uaauagauaa cgguauauau      840

cauauagcac cuuuagggaa guuacauagc aauaauaaaa uaggaauaga aacuuuaaca      900

gagguuauga aaguuuaucc uuauuuaagu augcaacauu uacaaucagc agaucaaauu      960

aagcgucauu augauucaaa agaugcugaa ggaaacaaaa uaccuuuaga uaaguuuaaa     1020

aaggaaggaa aagaaaaaua cuguccaaaa acuuauacau uugaugaugg aaaaguaaua     1080

auaaaagcug gugcuagagu agaagaagaa aaaguuaaaa gacuauacug ggcaucaaag     1140

gaaguuaacu cucaauucuu uagaguauac ggaauagaca aaccauuaga agaagguaau     1200

ccagaugaua uauuaacaau gguuaucuac aacagucccg aagaauauaa acucaauagu     1260

guucuauacg gauaugauac uaauaauggu gguauguaua uagagccaga aggaacuuuc     1320

uucaccuaug aaagagaagc ucaagaaagc acauacacau uagaagaauu auuuagacau     1380

gaauauacac auuauuugca aggaagauau gcaguuccag gacaaugggg aagaacaaaa     1440

cuuuaugaca augauagauu aacuugguau gaagaaggug gagcagaauu auuugcaggu     1500

ucuacuagaa cuucuggaau auuaccaaga aagaguauag uaucaaauau ucauaauaca     1560

acaagaaaua auagauauaa gcugucagac acuguacauu cuaaauaugg ugcuaguuuu     1620

gaguucuaua auuaugcaug uauguuuaug gauuauaugu auaauaaaga uauggguaua     1680

uuaaauaaac uaaaugaucu ugcaaaaaau aaugauguug auggauauga uaauuauauu     1740

agagauuuaa guucuaauua ugcuuuaaau gauaaauauc aagaucauau gcaggagcgc     1800

auagauaauu augaaaauuu aacagugccu uuuguagcug augauuauuu aguaaggcau     1860

gcuuauaaga acccuaauga aauuuauucu gaaauaucug aaguagcaaa auuaaaggau     1920

gcuaagagug aaguuaagaa aucacaauau uuuaguaccu uuacuuugag agguaguuac     1980

acagguggag caucuaaggg gaaauuagaa gaucaaaaag caaugaauaa guuuauagau     2040

gauucacuua agaaauuaga uacguauucu uggagugggu auaaaacuuu aacugcuuau     2100

uucacuaauu auaaaguuga cucuucaaau agaguuacuu augauguagu auuccacgga     2160

uauuuaccaa acgaagguga uuccaaaaau ucauuaccuu auggcaagau caauggaacu     2220

uacaagggaa cagagaaaga aaaaaucaaa uucucuagug aaggcucuuu cgauccagau     2280

gguaaaauag uuucuuauga augggauuuc ggagauggua auaagaguaa ugaggaaaau     2340

ccagagcauu cauaugacaa gguaggaacu uauacaguga aauuaaaagu uacugaugac     2400

aagggagaau cuucaguauc uacuacuacu gcagaaauaa aggaucuuuc agaaaauaaa     2460

cuuccaguua uauauaugca uguaccuaaa uccggagccu uaaaucaaaa aguuguuuuc     2520

uauggaaaag gaacauauga cccagaugga ucuaucgcag gauaucaaug ggacuuuggu     2580

gauggaagug auuuuagcag ugaacaaaac ccaagccaug uauauacuaa aaaaggugaa     2640

uauacuguaa cauuaagagu aauggauagu aguggacaaa ugagugaaaa aacuaugaag     2700

auuaagauua cagauccggu auauccaaua ggcacugaaa aagaaccaaa uaacaguaaa     2760

gaaacugcaa gugguccaau aguaccaggu auaccuguua guggaaccau agaaaauaca     2820

agugaucaag auuauuucua uuuugauguu auaacaccag gagaaguaaa aauagauaua     2880

aauaaauuag gguacggagg agcuacuugg guaguauaug augaaaauaa uaaugcagua     2940

ucuuaugcca cugaugaugg gcaaaauuua aguggaaagu uuaaggcaga uaaaccaggu     3000

agauauuaca uccaucuuua cauguuuaau gguaguuaua ugccauauag aauuaauaua     3060

gaagguucag uaggaagaua aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  1390
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (wt)

<400>  1390
gggagaaagc uuaccaugaa guggguaacc uuuauuuccc uucuuuuucu cuuuagcucg       60

gcuuauuccg uacaaaauga aaguaagagg uauacaguau cauauuuaaa gacuuuaaau      120

uauuaugacu uaguagauuu gcuuguuaag acugaaauug agaauuuacc agaccuuuuu      180

caguauaguu cagaugcaaa agaguucuau ggaaauaaaa cucguaugag cuuuaucaug      240

gaugaaauug guagaagggc accucaguau acagagauag aucauaaagg uauuccuacu      300

uuaguagaag uuguaagagc uggauuuuac uuaggauucc auaacaagga auugaaugaa      360

auaaacaaga ggucuuuuaa agaaagggua auaccuucua uauuagcaau ucaaaaaaau      420

ccuaauuuua aacuagguac ugaaguucaa gauaaaauag uaucugcaac aggacuuuua      480

gcugguaaug aaacagcgcc uccagaaguu guaaauaauu uuacaccaau acuucaagac      540

uguauaaaga auauagacag auacgcucuu gaugauuuaa agucaaaagc auuauuuaau      600

guuuuagcug caccuaccua ugauauaacu gaguauuuaa gagcuacuaa agaaaaacca      660

gaaaacacuc cuugguaugg uaaaauagau ggguuuauaa augaacuuaa aaaguuagcu      720

cuuuauggaa aaauaaauga uaauaacucu uggauaauag auaacgguau auaucauaua      780

gcaccuuuag ggaaguuaca uagcaauaau aaaauaggaa uagaaacuuu aacagagguu      840

augaaaguuu auccuuauuu aaguaugcaa cauuuacaau cagcagauca aauuaagcgu      900

cauuaugauu caaaagaugc ugaaggaaac aaaauaccuu uagauaaguu uaaaaaggaa      960

ggaaaagaaa aauacugucc aaaaacuuau acauuugaug auggaaaagu aauaauaaaa     1020

gcuggugcua gaguagaaga agaaaaaguu aaaagacuau acugggcauc aaaggaaguu     1080

aacucucaau ucuuuagagu auacggaaua gacaaaccau uagaagaagg uaauccagau     1140

gauauauuaa caaugguuau cuacaacagu cccgaagaau auaaacucaa uaguguucua     1200

uacggauaug auacuaauaa uggugguaug uauauagagc cagaaggaac uuucuucacc     1260

uaugaaagag aagcucaaga aagcacauac acauuagaag aauuauuuag acaugaauau     1320

acacauuauu ugcaaggaag auaugcaguu ccaggacaau ggggaagaac aaaacuuuau     1380

gacaaugaua gauuaacuug guaugaagaa gguggagcag aauuauuugc agguucuacu     1440

agaacuucug gaauauuacc aagaaagagu auaguaucaa auauucauaa uacaacaaga     1500

aauaauagau auaagcuuuc agacacugua cauucuaaau auggugcuag uuuugaauuc     1560

uauaauuaug cauguauguu uauggauuau auguauaaua aagauauggg uauauuaaau     1620

aaacuaaaug aucuugcaaa aaauaaugau guugauggau augauaauua uauuagagau     1680

uuaaguucua auuaugcuuu aaaugauaaa uaucaagauc auaugcagga gcgcauagau     1740

aauuaugaaa auuuaacagu gccuuuugua gcugaugauu auuuaguaag gcaugcuuau     1800

aagaacccua augaaauuua uucugaaaua ucugaaguag caaaauuaaa ggaugcuaag     1860

agugaaguua agaaaucaca auauuuuagu accuuuacuu ugagagguag uuacacaggu     1920

ggagcaucua aggggaaauu agaagaucaa aaagcaauga auaaguuuau agaugauuca     1980

cuuaagaaau uagauacgua uucuuggagu ggguauaaaa cuuuaacugc uuauuucacu     2040

aauuauaaag uugacucuuc aaauagaguu acuuaugaug uaguauucca cggauauuua     2100

ccaaacgaag gugauuccaa aaauucauua ccuuauggca agaucaaugg aacuuacaag     2160

ggaacagaga aagaaaaaau caaauucucu agugaaggcu cuuucgaucc agaugguaaa     2220

auaguuucuu augaauggga uuucggagau gguaauaaga guaaugagga aaauccagag     2280

cauucauaug acaagguagg aacuuauaca gugaaauuaa aaguuacuga ugacaaggga     2340

gaaucuucag uaucuacuac uacugcagaa auaaaggauc uuucagaaaa uaaacuucca     2400

guuauauaua ugcauguacc uaaauccgga gccuuaaauc aaaaaguugu uuucuaugga     2460

aaaggaacau augacccaga uggaucuauc gcaggauauc aaugggacuu uggugaugga     2520

agugauuuua gcagugaaca aaacccaagc cauguauaua cuaaaaaagg ugaauauacu     2580

guaacauuaa gaguaaugga uaguagugga caaaugagug aaaaaacuau gaagauuaag     2640

auuacagauc cgguauaucc aauaggcacu gaaaaagaac caaauaacag uaaagaaacu     2700

gcaagugguc caauaguacc agguauaccu guuaguggaa ccauagaaaa uacaagugau     2760

caagauuauu ucuauuuuga uguuauaaca ccaggagaag uaaaaauaga uauaaauaaa     2820

uuaggguacg gaggagcuac uuggguagua uaugaugaaa auaauaaugc aguaucuuau     2880

gccacugaug augggcaaaa uuuaagugga aaguuuaagg cagauaaacc agguagauau     2940

uacauccauc uuuacauguu uaaugguagu uauaugccau auagaauuaa uauagaaggu     3000

ucaguaggaa gauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1391
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (wt)

<400>  1391
gggagaaagc uuaccaugaa guggguaacc uuuauuuccc uucuuuuucu cuuuagcucg       60

gcuuauuccg uacaaaauga aaguaagagg uauacaguau cauauuuaaa gacuuuaaau      120

uauuaugacu uaguagauuu gcuuguuaag acugaaauug agaauuuacc agaccuuuuu      180

caguauaguu cagaugcaaa agaguucuau ggaaauaaaa cucguaugag cuuuaucaug      240

gaugaaauug guagaagggc accucaguau acagagauag aucauaaagg uauuccuacu      300

uuaguagaag uuguaagagc uggauuuuac uuaggauucc auaacaagga auugaaugaa      360

auaaacaaga ggucuuuuaa agaaagggua auaccuucua uauuagcaau ucaaaaaaau      420

ccuaauuuua aacuagguac ugaaguucaa gauaaaauag uaucugcaac aggacuuuua      480

gcugguaaug aaacagcgcc uccagaaguu guaaauaauu uuacaccaau acuucaagac      540

uguauaaaga auauagacag auacgcucuu gaugauuuaa agucaaaagc auuauuuaau      600

guuuuagcug caccuaccua ugauauaacu gaguauuuaa gagcuacuaa agaaaaacca      660

gaaaacacuc cuugguaugg uaaaauagau ggguuuauaa augaacuuaa aaaguuagcu      720

cuuuauggaa aaauaaauga uaauaacucu uggauaauag auaacgguau auaucauaua      780

gcaccuuuag ggaaguuaca uagcaauaau aaaauaggaa uagaaacuuu aacagagguu      840

augaaaguuu auccuuauuu aaguaugcaa cauuuacaau cagcagauca aauuaagcgu      900

cauuaugauu caaaagaugc ugaaggaaac aaaauaccuu uagauaaguu uaaaaaggaa      960

ggaaaagaaa aauacugucc aaaaacuuau acauuugaug auggaaaagu aauaauaaaa     1020

gcuggugcua gaguagaaga agaaaaaguu aaaagacuau acugggcauc aaaggaaguu     1080

aacucucaau ucuuuagagu auacggaaua gacaaaccau uagaagaagg uaauccagau     1140

gauauauuaa caaugguuau cuacaacagu cccgaagaau auaaacucaa uaguguucua     1200

uacggauaug auacuaauaa uggugguaug uauauagagc cagaaggaac uuucuucacc     1260

uaugaaagag aagcucaaga aagcacauac acauuagaag aauuauuuag acaugaauau     1320

acacauuauu ugcaaggaag auaugcaguu ccaggacaau ggggaagaac aaaacuuuau     1380

gacaaugaua gauuaacuug guaugaagaa gguggagcag aauuauuugc agguucuacu     1440

agaacuucug gaauauuacc aagaaagagu auaguaucaa auauucauaa uacaacaaga     1500

aauaauagau auaagcuguc agacacugua cauucuaaau auggugcuag uuuugaguuc     1560

uauaauuaug cauguauguu uauggauuau auguauaaua aagauauggg uauauuaaau     1620

aaacuaaaug aucuugcaaa aaauaaugau guugauggau augauaauua uauuagagau     1680

uuaaguucua auuaugcuuu aaaugauaaa uaucaagauc auaugcagga gcgcauagau     1740

aauuaugaaa auuuaacagu gccuuuugua gcugaugauu auuuaguaag gcaugcuuau     1800

aagaacccua augaaauuua uucugaaaua ucugaaguag caaaauuaaa ggaugcuaag     1860

agugaaguua agaaaucaca auauuuuagu accuuuacuu ugagagguag uuacacaggu     1920

ggagcaucua aggggaaauu agaagaucaa aaagcaauga auaaguuuau agaugauuca     1980

cuuaagaaau uagauacgua uucuuggagu ggguauaaaa cuuuaacugc uuauuucacu     2040

aauuauaaag uugacucuuc aaauagaguu acuuaugaug uaguauucca cggauauuua     2100

ccaaacgaag gugauuccaa aaauucauua ccuuauggca agaucaaugg aacuuacaag     2160

ggaacagaga aagaaaaaau caaauucucu agugaaggcu cuuucgaucc agaugguaaa     2220

auaguuucuu augaauggga uuucggagau gguaauaaga guaaugagga aaauccagag     2280

cauucauaug acaagguagg aacuuauaca gugaaauuaa aaguuacuga ugacaaggga     2340

gaaucuucag uaucuacuac uacugcagaa auaaaggauc uuucagaaaa uaaacuucca     2400

guuauauaua ugcauguacc uaaauccgga gccuuaaauc aaaaaguugu uuucuaugga     2460

aaaggaacau augacccaga uggaucuauc gcaggauauc aaugggacuu uggugaugga     2520

agugauuuua gcagugaaca aaacccaagc cauguauaua cuaaaaaagg ugaauauacu     2580

guaacauuaa gaguaaugga uaguagugga caaaugagug aaaaaacuau gaagauuaag     2640

auuacagauc cgguauaucc aauaggcacu gaaaaagaac caaauaacag uaaagaaacu     2700

gcaagugguc caauaguacc agguauaccu guuaguggaa ccauagaaaa uacaagugau     2760

caagauuauu ucuauuuuga uguuauaaca ccaggagaag uaaaaauaga uauaaauaaa     2820

uuaggguacg gaggagcuac uuggguagua uaugaugaaa auaauaaugc aguaucuuau     2880

gccacugaug augggcaaaa uuuaagugga aaguuuaagg cagauaaacc agguagauau     2940

uacauccauc uuuacauguu uaaugguagu uauaugccau auagaauuaa uauagaaggu     3000

ucaguaggaa gauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1392
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (wt)

<400>  1392
gggagaaagc uuaccaugaa guggguaacc uuuauuuccc uucuuuuucu cuuuagcucg       60

gcuuauucca ugaaaaggaa auguuuaucu aaaaggcuua uguuagcuau aacaauggcu      120

acaauauuua cagugaacag uacauuacca auuuaugcag cuguagauaa aaauaaugca      180

acagcagcua gaaggcggcg caagagagua caaaaugaaa guaagaggua uacaguauca      240

uauuuaaaga cuuuaaauua uuaugacuua guagauuugc uuguuaagac ugaaauugag      300

aauuuaccag accuuuuuca guauaguuca gaugcaaaag aguucuaugg aaauaaaacu      360

cguaugagcu uuaucaugga ugaaauuggu agaagggcac cucaguauac agagauagau      420

cauaaaggua uuccuacuuu aguagaaguu guaagagcug gauuuuacuu aggauuccau      480

aacaaggaau ugaaugaaau aaacaagagg ucuuuuaaag aaaggguaau accuucuaua      540

uuagcaauuc aaaaaaaucc uaauuuuaaa cuagguacug aaguucaaga uaaaauagua      600

ucugcaacag gacuuuuagc ugguaaugaa acagcgccuc cagaaguugu aaauaauuuu      660

acaccaauac uucaagacug uauaaagaau auagacagau acgcucuuga ugauuuaaag      720

ucaaaagcau uauuuaaugu uuuagcugca ccuaccuaug auauaacuga guauuuaaga      780

gcuacuaaag aaaaaccaga aaacacuccu ugguauggua aaauagaugg guuuauaaau      840

gaacuuaaaa aguuagcucu uuauggaaaa auaaaugaua auaacucuug gauaauagau      900

aacgguauau aucauauagc accuuuaggg aaguuacaua gcaauaauaa aauaggaaua      960

gaaacuuuaa cagagguuau gaaaguuuau ccuuauuuaa guaugcaaca uuuacaauca     1020

gcagaucaaa uuaagcguca uuaugauuca aaagaugcug aaggaaacaa aauaccuuua     1080

gauaaguuua aaaaggaagg aaaagaaaaa uacuguccaa aaacuuauac auuugaugau     1140

ggaaaaguaa uaauaaaagc uggugcuaga guagaagaag aaaaaguuaa aagacuauac     1200

ugggcaucaa aggaaguuaa cucucaauuc uuuagaguau acggaauaga caaaccauua     1260

gaagaaggua auccagauga uauauuaaca augguuaucu acaacagucc cgaagaauau     1320

aaacucaaua guguucuaua cggauaugau acuaauaaug gugguaugua uauagagcca     1380

gaaggaacuu ucuucaccua ugaaagagaa gcucaagaaa gcacauacac auuagaagaa     1440

uuauuuagac augaauauac acauuauuug caaggaagau augcaguucc aggacaaugg     1500

ggaagaacaa aacuuuauga caaugauaga uuaacuuggu augaagaagg uggagcagaa     1560

uuauuugcag guucuacuag aacuucugga auauuaccaa gaaagaguau aguaucaaau     1620

auucauaaua caacaagaaa uaauagauau aagcuuucag acacuguaca uucuaaauau     1680

ggugcuaguu uugaauucua uaauuaugca uguauguuua uggauuauau guauaauaaa     1740

gauaugggua uauuaaauaa acuaaaugau cuugcaaaaa auaaugaugu ugauggauau     1800

gauaauuaua uuagagauuu aaguucuaau uaugcuuuaa augauaaaua ucaagaucau     1860

augcaggagc gcauagauaa uuaugaaaau uuaacagugc cuuuuguagc ugaugauuau     1920

uuaguaaggc augcuuauaa gaacccuaau gaaauuuauu cugaaauauc ugaaguagca     1980

aaauuaaagg augcuaagag ugaaguuaag aaaucacaau auuuuaguac cuuuacuuug     2040

agagguaguu acacaggugg agcaucuaag gggaaauuag aagaucaaaa agcaaugaau     2100

aaguuuauag augauucacu uaagaaauua gauacguauu cuuggagugg guauaaaacu     2160

uuaacugcuu auuucacuaa uuauaaaguu gacucuucaa auagaguuac uuaugaugua     2220

guauuccacg gauauuuacc aaacgaaggu gauuccaaaa auucauuacc uuauggcaag     2280

aucaauggaa cuuacaaggg aacagagaaa gaaaaaauca aauucucuag ugaaggcucu     2340

uucgauccag augguaaaau aguuucuuau gaaugggauu ucggagaugg uaauaagagu     2400

aaugaggaaa auccagagca uucauaugac aagguaggaa cuuauacagu gaaauuaaaa     2460

guuacugaug acaagggaga aucuucagua ucuacuacua cugcagaaau aaaggaucuu     2520

ucagaaaaua aacuuccagu uauauauaug cauguaccua aauccggagc cuuaaaucaa     2580

aaaguuguuu ucuauggaaa aggaacauau gacccagaug gaucuaucgc aggauaucaa     2640

ugggacuuug gugauggaag ugauuuuagc agugaacaaa acccaagcca uguauauacu     2700

aaaaaaggug aauauacugu aacauuaaga guaauggaua guaguggaca aaugagugaa     2760

aaaacuauga agauuaagau uacagauccg guauauccaa uaggcacuga aaaagaacca     2820

aauaacagua aagaaacugc aaguggucca auaguaccag guauaccugu uaguggaacc     2880

auagaaaaua caagugauca agauuauuuc uauuuugaug uuauaacacc aggagaagua     2940

aaaauagaua uaaauaaauu aggguacgga ggagcuacuu ggguaguaua ugaugaaaau     3000

aauaaugcag uaucuuaugc cacugaugau gggcaaaauu uaaguggaaa guuuaaggca     3060

gauaaaccag guagauauua cauccaucuu uacauguuua augguaguua uaugccauau     3120

agaauuaaua uagaagguuc aguaggaaga uaaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  1393
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (wt)

<400>  1393
gggagaaagc uuaccaugaa guggguaacc uuuauuuccc uucuuuuucu cuuuagcucg       60

gcuuauucca ugaaaaggaa auguuuaucu aaaaggcuua uguuagcuau aacaauggcu      120

acaauauuua cagugaacag uacauuacca auuuaugcag cuguagauaa aaauaaugca      180

acagcagcua gaaggcggcg caagagagua caaaaugaaa guaagaggua uacaguauca      240

uauuuaaaga cuuuaaauua uuaugacuua guagauuugc uuguuaagac ugaaauugag      300

aauuuaccag accuuuuuca guauaguuca gaugcaaaag aguucuaugg aaauaaaacu      360

cguaugagcu uuaucaugga ugaaauuggu agaagggcac cucaguauac agagauagau      420

cauaaaggua uuccuacuuu aguagaaguu guaagagcug gauuuuacuu aggauuccau      480

aacaaggaau ugaaugaaau aaacaagagg ucuuuuaaag aaaggguaau accuucuaua      540

uuagcaauuc aaaaaaaucc uaauuuuaaa cuagguacug aaguucaaga uaaaauagua      600

ucugcaacag gacuuuuagc ugguaaugaa acagcgccuc cagaaguugu aaauaauuuu      660

acaccaauac uucaagacug uauaaagaau auagacagau acgcucuuga ugauuuaaag      720

ucaaaagcau uauuuaaugu uuuagcugca ccuaccuaug auauaacuga guauuuaaga      780

gcuacuaaag aaaaaccaga aaacacuccu ugguauggua aaauagaugg guuuauaaau      840

gaacuuaaaa aguuagcucu uuauggaaaa auaaaugaua auaacucuug gauaauagau      900

aacgguauau aucauauagc accuuuaggg aaguuacaua gcaauaauaa aauaggaaua      960

gaaacuuuaa cagagguuau gaaaguuuau ccuuauuuaa guaugcaaca uuuacaauca     1020

gcagaucaaa uuaagcguca uuaugauuca aaagaugcug aaggaaacaa aauaccuuua     1080

gauaaguuua aaaaggaagg aaaagaaaaa uacuguccaa aaacuuauac auuugaugau     1140

ggaaaaguaa uaauaaaagc uggugcuaga guagaagaag aaaaaguuaa aagacuauac     1200

ugggcaucaa aggaaguuaa cucucaauuc uuuagaguau acggaauaga caaaccauua     1260

gaagaaggua auccagauga uauauuaaca augguuaucu acaacagucc cgaagaauau     1320

aaacucaaua guguucuaua cggauaugau acuaauaaug gugguaugua uauagagcca     1380

gaaggaacuu ucuucaccua ugaaagagaa gcucaagaaa gcacauacac auuagaagaa     1440

uuauuuagac augaauauac acauuauuug caaggaagau augcaguucc aggacaaugg     1500

ggaagaacaa aacuuuauga caaugauaga uuaacuuggu augaagaagg uggagcagaa     1560

uuauuugcag guucuacuag aacuucugga auauuaccaa gaaagaguau aguaucaaau     1620

auucauaaua caacaagaaa uaauagauau aagcugucag acacuguaca uucuaaauau     1680

ggugcuaguu uugaguucua uaauuaugca uguauguuua uggauuauau guauaauaaa     1740

gauaugggua uauuaaauaa acuaaaugau cuugcaaaaa auaaugaugu ugauggauau     1800

gauaauuaua uuagagauuu aaguucuaau uaugcuuuaa augauaaaua ucaagaucau     1860

augcaggagc gcauagauaa uuaugaaaau uuaacagugc cuuuuguagc ugaugauuau     1920

uuaguaaggc augcuuauaa gaacccuaau gaaauuuauu cugaaauauc ugaaguagca     1980

aaauuaaagg augcuaagag ugaaguuaag aaaucacaau auuuuaguac cuuuacuuug     2040

agagguaguu acacaggugg agcaucuaag gggaaauuag aagaucaaaa agcaaugaau     2100

aaguuuauag augauucacu uaagaaauua gauacguauu cuuggagugg guauaaaacu     2160

uuaacugcuu auuucacuaa uuauaaaguu gacucuucaa auagaguuac uuaugaugua     2220

guauuccacg gauauuuacc aaacgaaggu gauuccaaaa auucauuacc uuauggcaag     2280

aucaauggaa cuuacaaggg aacagagaaa gaaaaaauca aauucucuag ugaaggcucu     2340

uucgauccag augguaaaau aguuucuuau gaaugggauu ucggagaugg uaauaagagu     2400

aaugaggaaa auccagagca uucauaugac aagguaggaa cuuauacagu gaaauuaaaa     2460

guuacugaug acaagggaga aucuucagua ucuacuacua cugcagaaau aaaggaucuu     2520

ucagaaaaua aacuuccagu uauauauaug cauguaccua aauccggagc cuuaaaucaa     2580

aaaguuguuu ucuauggaaa aggaacauau gacccagaug gaucuaucgc aggauaucaa     2640

ugggacuuug gugauggaag ugauuuuagc agugaacaaa acccaagcca uguauauacu     2700

aaaaaaggug aauauacugu aacauuaaga guaauggaua guaguggaca aaugagugaa     2760

aaaacuauga agauuaagau uacagauccg guauauccaa uaggcacuga aaaagaacca     2820

aauaacagua aagaaacugc aaguggucca auaguaccag guauaccugu uaguggaacc     2880

auagaaaaua caagugauca agauuauuuc uauuuugaug uuauaacacc aggagaagua     2940

aaaauagaua uaaauaaauu aggguacgga ggagcuacuu ggguaguaua ugaugaaaau     3000

aauaaugcag uaucuuaugc cacugaugau gggcaaaauu uaaguggaaa guuuaaggca     3060

gauaaaccag guagauauua cauccaucuu uacauguuua augguaguua uaugccauau     3120

agaauuaaua uagaagguuc aguaggaaga uaaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  1394
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (wt)

<400>  1394
gggagaaagc uuaccauggg gaccuggauu uuauuugccu gccuccuggg agcagcuuuu       60

gccaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug      120

cuuaccccuu ugaaguggua ccagagcaua aggccaccgu acccuuccua ugguuacgag      180

cccaugggug gauggcugca ccaccaaauc auccccgugc ugucccaaca gcaccccccg      240

acucacaccc ugcagccuca ucaccacauc ccaguggugc cagcucagca gcccgugauc      300

ccccagcaac caaugaugcc cguuccuggc caacacucca ugacuccaau ccaacaccac      360

cagccaaacc ucccuccgcc cgcccagcag cccuaccagc cccagccugu ucagccacag      420

ccucaccagc ccaugcagcc ccagccaccu gugcacccca ugcagccccu gccgccacag      480

ccaccucugc cuccgauguu ccccaugcag ccccugccuc ccaugcuucc ugaucugacu      540

cuggaagcuu ggccaucaac agacaagacc aagcgggagg aaguggauua aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  1395
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (wt)

<400>  1395
gggagaaagc uuaccauggg gaccuggauu uuauuugccu gccuccuggg agcagcuuuu       60

gccaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug      120

cuuaccccuu ugaaguggua ccagagcaua aggccaccgu acccuuccua ugguuacgag      180

cccaugggug gauggcugca ccaccaaauc auccccgugc ugucccaaca gcaccccccg      240

acucacaccc ugcagccuca ucaccacauc ccaguggugc cagcucagca gcccgugauc      300

ccccagcaac caaugaugcc cguuccuggc caacacucca ugacuccaau ccaacaccac      360

cagccaaacc ucccuccgcc cgcccagcag cccuaccagc cccagccugu ucagccacag      420

ccucaccagc ccaugcagcc ccagccaccu gugcacccca ugcagccccu gccgccacag      480

ccaccucugc cuccgauguu ccccaugcag ccccugccuc ccaugcuucc ugaucugacu      540

cuggaagcau ggccaucaac agacaagacc aagcgggagg aaguggauua aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  1396
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (wt)

<400>  1396
gggagaaagc uuaccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc       60

agcuaugagg ugcuuacccc uuugaagugg uaccagagca uaaggccacc guacccuucc      120

uaugguuacg agcccauggg uggaugguaa ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  1397
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (wt)

<400>  1397
gggagaaagc uuaccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc       60

agcuaugagg ugcuuacccc uuugaagugg uaccagagca uaaggccacc ucccaugcuu      120

ccugaucuga cucuggaagc uuggccauca acagacaaga ccaagcggga ggaaguggau      180

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  1398
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (wt)

<400>  1398
gggagaaagc uuaccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc       60

agcuaugagg ugcuuacccc uuugaagugg uaccagagca uaaggccacc ucccaugcuu      120

ccugaucuga cucuggaagc auggccauca acagacaaga ccaagcggga ggaaguggau      180

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  1399
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (wt)

<400>  1399
gggagaaagc uuaccauggc cgucauggcg ccccgaaccc ucguccugcu acucucgggg       60

gcucuggccc ugacccagac cugggcgaug ccucuaccac cucauccugg gcacccuggu      120

uauaucaacu ucagcuauga ggugcuuacc ccuuugaagu gguaccagag cauaaggcca      180

ccguacccuu ccuaugguua cgagcccaug gguggauggu aaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  1400
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (wt)

<400>  1400
gggagaaagc uuaccauggc cgucauggcg ccccgaaccc ucguccugcu acucucgggg       60

gcucuggccc ugacccagac cugggcgaug ccucuaccac cucauccugg gcacccuggu      120

uauaucaacu ucagcuauga ggugcuuacc ccuuugaagu gguaccagag cauaaggcca      180

ccucccaugc uuccugaucu gacucuggaa gcauggccau caacagacaa gaccaagcgg      240

gaggaagugg auuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  1401
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (wt)

<400>  1401
gggagaaagc uuaccauggg gaccuggauu uuguuugccu gccuuguggg agcagcuuuu       60

gccaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug      120

cucaccccuu ugaaguggua ccagagcaug auaagaccac cauacucuuc cuaugguuac      180

gagcccaugg guggauggcu gcaccaccaa aucauccccg ugguguccca acagcacccc      240

cugacucaca cccugcaguc ucaucaccac aucccagugg ugccagcuca gcagcccagg      300

guccgccagc aagcacugau gccuguuccu ggccagcaau ccaugacucc aacccaacac      360

caucagccaa accucccucu gccugcccag cagcccuucc agccccagcc uguucagcca      420

cagccucacc agcccaugca gccccagcca ccugugcaac ccaugcagcc ccugcugcca      480

cagccaccuc ugccuccaau guucccccug cggccccugc cccccauacu uccugaucug      540

caucuggaag cuuggccagc aacagacaag accaagcagg aggaagugga uuaaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  1402
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (wt)

<400>  1402
gggagaaagc uuaccauggg gaccuggauu uuguuugccu gccuuguggg agcagcuuuu       60

gccaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug      120

cucaccccuu ugaaguggua ccagagcaug auaagaccac cauacucuuc cuaugguuac      180

gagcccaugg guggauggcu gcaccaccaa aucauccccg ugguguccca acagcacccc      240

cugacucaca cccugcaguc ucaucaccac aucccagugg ugccagcuca gcagcccagg      300

guccgccagc aagcacugau gccuguuccu ggccagcaau ccaugacucc aacccaacac      360

caucagccaa accucccucu gccugcccag cagcccuucc agccccagcc uguucagcca      420

cagccucacc agcccaugca gccccagcca ccugugcaac ccaugcagcc ccugcugcca      480

cagccaccuc ugccuccaau guucccccug cggccccugc cccccauacu uccugaucug      540

caucuggaag cauggccagc aacagacaag accaagcagg aggaagugga uuaaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  1403
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (wt)

<400>  1403
gggagaaagc uuaccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc       60

agcuaugagg ugcucacccc uuugaagugg uaccagagca ugauaagacc accauacucu      120

uccuaugguu acgagcccau ggguggaugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1404
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (wt)

<400>  1404
gggagaaagc uuaccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc       60

agcuaugagg ugcucacccc uuugaagugg uaccagagca ugauaagacc accccccaua      120

cuuccugauc ugcaucugga agcuuggcca gcaacagaca agaccaagca ggaggaagug      180

gauuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1405
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (wt)

<400>  1405
gggagaaagc uuaccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc       60

agcuaugagg ugcucacccc uuugaagugg uaccagagca ugauaagacc accccccaua      120

cuuccugauc ugcaucugga agcauggcca gcaacagaca agaccaagca ggaggaagug      180

gauuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1406
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (wt)

<400>  1406
gggagaaagc uuaccauggc cgucauggcg ccccgaaccc ucguccugcu acucucgggg       60

gcucuggccc ugacccagac cugggcgaug ccucuaccac cucauccugg gcacccuggu      120

uauaucaacu ucagcuauga ggugcucacc ccuuugaagu gguaccagag caugauaaga      180

ccaccauacu cuuccuaugg uuacgagccc auggguggau gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1407
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (wt)

<400>  1407
gggagaaagc uuaccauggc cgucauggcg ccccgaaccc ucguccugcu acucucgggg       60

gcucuggccc ugacccagac cugggcgaug ccucuaccac cucauccugg gcacccuggu      120

uauaucaacu ucagcuauga ggugcucacc ccuuugaagu gguaccagag caugauaaga      180

ccacccccca uacuuccuga ucugcaucug gaagcauggc cagcaacaga caagaccaag      240

caggaggaag uggauuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1408
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (wt)

<400>  1408
gggagaaagc uuaccauggg gaccuggauu uuguuugcuu gccuccuggg agcagccuuc       60

ucuaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug      120

cuuaccccuc ugaaguggua ccagaacaug auaagacauc cguacacuuc cuauggguac      180

gaacccaugg guggauggcu gcaccaccaa aucauacccg uggugucgca gcagacuccc      240

cagagucaug cccuucagcc ucaucaccac auccccaugg ugccagcuca acagcccggg      300

aucccccagc agccaaugau gccacuuccu ggccaacacu ccaugacucc aacccaacac      360

caccagccaa accucccucu gcccgcccag cagcccuucc agccccagcc cguccagccc      420

cagccucacc agccccugca gccccaguca cccaugcacc ccauccagcc cuugcugcca      480

cagccaccuc ugccuccgau guucuccaug cagucucugc uuccugaccu gccucuggaa      540

gcuuggccag caacagacaa gaccaagcgg gaggaagugg auuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1409
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (wt)

<400>  1409
gggagaaagc uuaccauggg gaccuggauu uuguuugcuu gccuccuggg agcagccuuc       60

ucuaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug      120

cuuaccccuc ugaaguggua ccagaacaug auaagacauc cguacacuuc cuauggguac      180

gaacccaugg guggauggcu gcaccaccaa aucauacccg uggugucgca gcagacuccc      240

cagagucaug cccuucagcc ucaucaccac auccccaugg ugccagcuca acagcccggg      300

aucccccagc agccaaugau gccacuuccu ggccaacacu ccaugacucc aacccaacac      360

caccagccaa accucccucu gcccgcccag cagcccuucc agccccagcc cguccagccc      420

cagccucacc agccccugca gccccaguca cccaugcacc ccauccagcc cuugcugcca      480

cagccaccuc ugccuccgau guucuccaug cagucucugc uuccugaccu gccucuggaa      540

gcauggccag caacagacaa gaccaagcgg gaggaagugg auuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1410
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (wt)

<400>  1410
gggagaaagc uuaccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc       60

agcuaugagg ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccguacacu      120

uccuaugggu acgaacccau ggguggaugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1411
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (wt)

<400>  1411
gggagaaagc uuaccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc       60

agcuaugagg ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccgucucug      120

cuuccugacc ugccucugga agcuuggcca gcaacagaca agaccaagcg ggaggaagug      180

gauuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1412
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (wt)

<400>  1412
gggagaaagc uuaccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc       60

agcuaugagg ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccgucucug      120

cuuccugacc ugccucugga agcauggcca gcaacagaca agaccaagcg ggaggaagug      180

gauuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1413
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (wt)

<400>  1413
gggagaaagc uuaccauggc cgucauggcg ccccgaaccc ucguccugcu acucucgggg       60

gcucuggccc ugacccagac cugggcgaug ccucuaccac cucauccugg gcacccuggu      120

uauaucaacu ucagcuauga ggugcuuacc ccucugaagu gguaccagaa caugauaaga      180

cauccguaca cuuccuaugg guacgaaccc auggguggau gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1414
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (wt)

<400>  1414
gggagaaagc uuaccauggc cgucauggcg ccccgaaccc ucguccugcu acucucgggg       60

gcucuggccc ugacccagac cugggcgaug ccucuaccac cucauccugg gcacccuggu      120

uauaucaacu ucagcuauga ggugcuuacc ccucugaagu gguaccagaa caugauaaga      180

cauccgucuc ugcuuccuga ccugccucug gaagcauggc cagcaacaga caagaccaag      240

cgggaggaag uggauuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1415
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (wt)

<400>  1415
gggagaaagc uuaccauggg gaccuggauu uuguuugcuu gccuccuggg agcagccuuc       60

ucuaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuauauaaga      120

cauccguaca cuuccuaugg guacgaaccc auggguggau ggcugcacca ccaaaucaua      180

cccguggugu cgcagcagac uccccagagu caugcccuuc agccucauca ccacaucccc      240

auggugccag cucaacagcc cgggaucccc cagcagccaa ugaugccacu uccuggccaa      300

cacuccauga cuccaaccca acaccaccag ccaaaccucc cucugcccgc ccagcagccc      360

uuccagcccc agcccgucca gccccagccu caccagcccc ugcagcccca gucacccaug      420

caccccaucc agcccuugcu gccacagcca ccucugccuc cgauguucuc caugcagucu      480

cugcuuccug accugccucu ggaagcuugg ccagcaacag acaagaccaa gcgggaggaa      540

guggauuaag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  1416
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (wt)

<400>  1416
gggagaaagc uuaccauggg gaccuggauu uucuuugccu gccuuuuggg agcaucccuu       60

gcuaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug      120

cuuaccccuc ugaaguggua ccagaacaug auaagacauc cguacacuuc cuauggguac      180

gaacccaugg guggauggcu gcaccaccaa aucauacccg uggugucgca gcagacuccc      240

cagagucaug cccuucagcc ucaucaccac auccccaugg ugccagcuca acagcccggg      300

aucccccagc agccaaugau gccacuuccu ggccaacacu ccaugacucc aacccaacac      360

caccagccaa accucccucu gcccgcccag cagcccuucc agccccagcc cguccagccc      420

cagccucacc agccccugca gccccaguca cccaugcacc ccauccagcc cuugcugcca      480

cagccaccuc ugccuccgau guucuccaug cagucucugc uuccugaccu gccucuggaa      540

gcuuggccag caacagacaa gaccaagcgg gaggaagugg auuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1417
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (wt)

<400>  1417
gggagaaagc uuaccauggg gaccuggauu uuguuugcuu gccuccuggg agcagccuuc       60

ucuaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug      120

cuuaccccuc ugaaguggua ccagaacaug auaagacauc cgucucugcu uccugaccug      180

ccucuggaag cuuggccagc aacagacaag accaagcggg aggaagugga uuaaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  1418
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (wt)

<400>  1418
gggagaaagc uuaccauggg gaccuggauu uuguuugcuu gccuccuggg agcagccuuc       60

ucuaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggac      120

uuauacuugg aggcuauccg uauugacagg acugcauucg ugcuuacccc ucugaagugg      180

uaccagaaca ugauaagaca uccguacacu uccuaugguu acgaacccau ggguggaugg      240

cugcaccacc aaaucauucc cguggugucg cagcagacuc cccagaguca ugcccuucag      300

ccucaucacc acauccccau ggugccagcu caacagcccg ggauccccca gcagccaaug      360

augccacuuc cuggccaaca cuccaugacu ccaacccaac accaccagcc aaaccucccu      420

cugcccgccc agcagcccuu ccagccccag cccguccagc cccagccuca ccagccccug      480

cagccccagu cacccaugca ccccauccag cccuugcugc cacagccacc ucugccuccg      540

auguucucca ugcagucucu gcuuccugac cugccucugg aagcuuggcc agcaacagac      600

aagaccaagc gggaggaagu ggauuaagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  1419
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (wt)

<400>  1419
gggagaaagc uuaccauggg gaccuggauu uuguuugcuu gccuccuggg agcagccuuc       60

ucuaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug      120

cuuaccccuc ugaaguggua ccagaacaug auaagacauc cgacucccca gagucaugcc      180

cuucagccuc aucaccacau ccccauggug ccagcucaac agcccgggau cccccagcag      240

ccaaugaugc cacuuccugg ccaacacucc augacuccaa cccaacacca ccagccaaac      300

cucccucugc ccgcccagca gcccuuccag ccccagcccg uccagcccca gccucaccag      360

ccccugcagc cccagucacc caugcacccc auccagcccu ugcugccaca gccaccucug      420

ccuccgaugu ucuccaugca gucucugcuu ccugaccugc cucuggaagc uuggccagca      480

acagacaaga ccaagcggga ggaaguggau uaaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  1420
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (wt)

<400>  1420
gggagaaagc uuaccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc       60

agcuaugagg ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccguacacu      120

uccuaugggu acgaacccau ggguggaugg cugcaccacc aaaucauacc cguggugucg      180

cagcagacuc cccagaguca ugcccuucag ccucaucacc acauccccau ggugccagcu      240

caacagcccg ggauccccca gcagccaaug augccacuuc cuggccaaca cuccaugacu      300

ccaacccaac accaccagcc aaaccucccu cugcccgccc agcagcccuu ccagccccag      360

cccguccagc cccagccuca ccagccccug cagccccagu cacccaugca ccccauccag      420

cccuugcugc cacagccacc ucugccuccg auguucucca ugcagucucu gcuuccugac      480

cugccucugg aagcuuggcc agcaacagac aagaccaagc gggaggaagu ggauuaagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  1421
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (wt)

<400>  1421
gggagaaagc uuaccaugcc cggcguggcc cgccugccgc ugcugcucgg gcugcugcug       60

cucccgcguc ccggccggcc gcuggacuug gccgacuaca ccuaugaccu ggcggaggag      120

gacgacucgg agccccucaa cuacaaagac cccugcaagg cggcugccuu ucuuggggac      180

auugcccugg acgaagagga ccugagggcc uuccagguac agcaggcugu ggaucucaga      240

cggcacacag cucguaaguc cuccaucaaa gcugcaguuc caggaaacac uucuaccccc      300

agcugccaga gcaccaacgg gcagccucag aggggagccu gugggagaug gagagguaga      360

ucccguagcc ggcgggcggc gacgucccga ccagagcgug uguggcccga uggggucauc      420

cccuuuguca uugggggaaa cuucacuggu agccagaggg cagucuuccg gcaggccaug      480

aggcacuggg agaagcacac cugugucacc uuccuggagc gcacugacga ggacagcuau      540

auuguguuca ccuaucgacc uugcgggugc ugcuccuacg ugggucgccg cggcgggggc      600

ccccaggcca ucuccaucgg caagaacugu gacaaguucg gcauuguggu ccacgagcug      660

ggccacgucg ucggcuucug gcacgaacac acucggccag accgggaccg ccacguuucc      720

aucguucgug agaacaucca gccagggcag gaguauaacu uccugaagau ggagccucag      780

gagguggagu cccuggggga gaccuaugac uucgacagca ucaugcauua cgcucggaac      840

acauucucca ggggcaucuu ccuggauacc auugucccca aguaugaggu gaacggggug      900

aaaccuccca uuggccaaag gacacggcuc agcaaggggg acauugccca agcccgcaag      960

cuuuacaagu gcccagccug uggagagacc cugcaagaca gcacaggcaa cuucuccucc     1020

ccugaauacc ccaauggcua cucugcucac augcacugcg uguggcgcau cucugucaca     1080

cccggggaga agaucauccu gaacuucacg ucccuggacc uguaccgcag ccgccugugc     1140

ugguacgacu auguggaggu ccgagauggc uucuggagga aggcgccccu ccgaggccgc     1200

uucugcgggu ccaaacuccc ugagccuauc gucuccacug acagccgccu cuggguugaa     1260

uuccgcagca gcagcaauug gguuggaaag ggcuucuuug cagucuacga agccaucugc     1320

gggggugaug ugaaaaagga cuauggccac auucaaucgc ccaacuaccc agacgauuac     1380

cggcccagca aagucugcau cuggcggauc caggugucug agggcuucca cgugggccuc     1440

acauuccagu ccuuugagau ugagcgccac gacagcugug ccuacgacua ucuggaggug     1500

cgcgacgggc acagugagag cagcacccuc aucgggcgcu acuguggcua ugagaagccu     1560

gaugacauca agagcacguc cagccgccuc uggcucaagu ucgucucuga cggguccauu     1620

aacaaagcgg gcuuugccgu caacuuuuuc aaagaggugg acgagugcuc ucggcccaac     1680

cgcgggggcu gugagcagcg gugccucaac acccugggca gcuacaagug cagcugugac     1740

cccggguacg agcuggcccc agacaagcgc cgcugugagg cugcuugugg cggauuccuc     1800

accaagcuca acggcuccau caccagcccg ggcuggccca aggaguaccc ccccaacaag     1860

aacugcaucu ggcagcuggu ggcccccacc caguaccgca ucucccugca guuugacuuc     1920

uuugagacag agggcaauga ugugugcaag uacgacuucg uggaggugcg caguggacuc     1980

acagcugacu ccaagcugca uggcaaguuc ugugguucug agaagcccga ggucaucacc     2040

ucccaguaca acaacaugcg cguggaguuc aaguccgaca acaccguguc caaaaagggc     2100

uucaaggccc acuucuucuc agacaaggac gagugcucca aggauaacgg cggcugccag     2160

caggacugcg ucaacacguu cggcaguuau gagugccaau gccgcagugg cuucguccuc     2220

caugacaaca agcacgacug caaagaagcc ggcugugacc acaaggugac auccaccagu     2280

gguaccauca ccagccccaa cuggccugac aaguauccca gcaagaagga gugcacgugg     2340

gccaucucca gcacccccgg gcaccggguc aagcugaccu ucauggagau ggacaucgag     2400

ucccagccug agugugccua cgaccaccua gagguguucg acgggcgaga cgccaaggcc     2460

cccguccucg gccgcuucug ugggagcaag aagcccgagc ccguccuggc cacaggcagc     2520

cgcauguucc ugcgcuucua cucagauaac ucgguccagc gaaagggcuu ccaggccucc     2580

cacgccacag agugcggggg ccagguacgg gcagacguga agaccaagga ccuuuacucc     2640

cacgcccagu uuggcgacaa caacuacccu gggggugugg acugugagug ggucauugug     2700

gccgaggaag gcuacggcgu ggagcucgug uuccagaccu uugaggugga ggaggagacc     2760

gacugcggcu augacuacau ggagcucuuc gacggcuacg acagcacagc ccccaggcug     2820

gggcgcuacu guggcucagg gccuccugag gagguguacu cggcgggaga uucuguccug     2880

gugaaguucc acucggauga caccaucacc aaaaaagguu uccaccugcg auacaccagc     2940

accaaguucc aggacacacu ccacagcagg aagugaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  1422
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (wt)

<400>  1422
gggagaaagc uuaccauggu ggccgggacc cgcugucuuc uagcguugcu gcuuccccag       60

guccuccugg gcggcgcggc uggccucguu ccggagcugg gccgcaggaa guucgcggcg      120

gcgucgucgg gccgccccuc aucccagccc ucugacgagg uccugagcga guucgaguug      180

cggcugcuca gcauguucgg ccugaaacag agacccaccc ccagcaggga cgccguggug      240

ccccccuaca ugcuagaccu guaucgcagg cacucagguc agccgggcuc acccgcccca      300

gaccaccggu uggagagggc agccagccga gccaacacug ugcgcagcuu ccaccaugaa      360

gaaucuuugg aagaacuacc agaaacgagu gggaaaacaa cccggagauu cuucuuuaau      420

uuaaguucua uccccacgga ggaguuuauc accucagcag agcuucaggu uuuccgagaa      480

cagaugcaag augcuuuagg aaacaauagc aguuuccauc accgaauuaa uauuuaugaa      540

aucauaaaac cugcaacagc caacucgaaa uuccccguga ccagacuuuu ggacaccagg      600

uuggugaauc agaaugcaag caggugggaa aguuuugaug ucacccccgc ugugaugcgg      660

uggacugcac agggacacgc caaccaugga uucguggugg aaguggccca cuuggaggag      720

aaacaaggug ucuccaagag acauguuagg auaagcaggu cuuugcacca agaugaacac      780

agcuggucac agauaaggcc auugcuagua acuuuuggcc augauggaaa agggcauccu      840

cuccacaaaa gagaaaaacg ucaagccaaa cacaaacagc ggaaacgccu uaaguccagc      900

uguaagagac acccuuugua cguggacuuc agugacgugg gguggaauga cuggauugug      960

gcucccccgg gguaucacgc cuuuuacugc cacggagaau gcccuuuucc ucuggcugau     1020

caucugaacu ccacuaauca ugccauuguu cagacguugg ucaacucugu uaacucuaag     1080

auuccuaagg caugcugugu cccgacagaa cucagugcua ucucgaugcu guaccuugac     1140

gagaaugaaa agguuguauu aaagaacuau caggacaugg uuguggaggg uugugggugu     1200

cgcuagggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  1423
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (wt)

<400>  1423
gggagaaagc uuaccaugau uccugguaac cgaaugcuga uggucguuuu auuaugccaa       60

guccugcuag gaggcgcgag ccaugcuagu uugauaccug agacggggaa gaaaaaaguc      120

gccgagauuc agggccacgc gggaggacgc cgcucagggc agagccauga gcuccugcgg      180

gacuucgagg cgacacuucu gcagauguuu gggcugcgcc gccgcccgca gccuagcaag      240

agugccguca uuccggacua caugcgggau cuuuaccggc uucagucugg ggaggaggag      300

gaagagcaga uccacagcac uggucuugag uauccugagc gcccggccag ccgggccaac      360

accgugagga gcuuccacca cgaagaacau cuggagaaca ucccagggac cagugaaaac      420

ucugcuuuuc guuuccucuu uaaccucagc agcaucccug agaacgaggu gaucuccucu      480

gcagagcuuc ggcucuuccg ggagcaggug gaccagggcc cugauuggga aaggggcuuc      540

caccguauaa acauuuauga gguuaugaag cccccagcag aaguggugcc ugggcaccuc      600

aucacacgac uacuggacac gagacugguc caccacaaug ugacacggug ggaaacuuuu      660

gaugugagcc cugcgguccu ucgcuggacc cgggagaagc agccaaacua ugggcuagcc      720

auugagguga cucaccucca ucagacucgg acccaccagg gccagcaugu caggauuagc      780

cgaucguuac cucaagggag ugggaauugg gcccagcucc ggccccuccu ggucaccuuu      840

ggccaugaug gccggggcca ugccuugacc cgacgccgga gggccaagcg uagcccuaag      900

caucacucac agcgggccag gaagaagaau aagaacugcc ggcgccacuc gcucuaugug      960

gacuucagcg augugggcug gaaugacugg auuguggccc caccaggcua ccaggccuuc     1020

uacugccaug gggacugccc cuuuccacug gcugaccacc ucaacucaac caaccaugcc     1080

auugugcaga cccuggucaa uucugucaau uccaguaucc ccaaagccug uugugugccc     1140

acugaacuga gugccaucuc caugcuguac cuggaugagu augauaaggu gguacugaaa     1200

aauuaucagg agaugguagu agagggaugu gggugccgcu gaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  1424
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (wt)

<400>  1424
gggagaaagc uuaccaugcc ggggcugggg cggagggcgc aguggcugug cugguggugg       60

gggcugcugu gcagcugcug cgggcccccg ccgcugcggc cgcccuugcc cgcugccgcg      120

gccgccgccg ccggggggca gcugcugggg gacggcggga gccccggccg cacggagcag      180

ccgccgccgu cgccgcaguc cuccucgggc uuccuguacc ggcggcucaa gacgcaggag      240

aagcgggaga ugcagaagga gaucuugucg gugcuggggc ucccgcaccg gccccggccc      300

cugcacggcc uccaacagcc gcagcccccg gcgcuccggc agcaggagga gcagcagcag      360

cagcagcagc ugccucgcgg agagcccccu cccgggcgac ugaaguccgc gccccucuuc      420

augcuggauc uguacaacgc ccuguccgcc gacaacgacg aggacggggc gucggagggg      480

gagaggcagc aguccuggcc ccacgaagca gccagcucgu cccagcgucg gcagccgccc      540

ccgggcgccg cgcacccgcu caaccgcaag agccuucugg cccccggauc uggcagcggc      600

ggcgcguccc cacugaccag cgcgcaggac agcgccuucc ucaacgacgc ggacaugguc      660

augagcuuug ugaaccuggu ggaguacgac aaggaguucu ccccucguca gcgacaccac      720

aaagaguuca aguucaacuu aucccagauu ccugagggug agguggugac ggcugcagaa      780

uuccgcaucu acaaggacug uguuaugggg aguuuuaaaa accaaacuuu ucuuaucagc      840

auuuaucaag ucuuacagga gcaucagcac agagacucug accuguuuuu guuggacacc      900

cguguaguau gggccucaga agaaggcugg cuggaauuug acaucacggc cacuagcaau      960

cuguggguug ugacuccaca gcauaacaug gggcuucagc ugagcguggu gacaagggau     1020

ggaguccacg uccacccccg agccgcaggc cuggugggca gagacggccc uuacgacaag     1080

cagcccuuca ugguggcuuu cuucaaagug agugaggugc acgugcgcac caccagguca     1140

gccuccagcc ggcgccgaca acagagucgu aaucgcucua cccaguccca ggacguggcg     1200

cgggucucca gugcuucaga uuacaacagc agugaauuga aaacagccug caggaagcau     1260

gagcuguaug ugaguuucca agaccuggga uggcaggacu ggaucauugc acccaagggc     1320

uaugcugcca auuacuguga uggagaaugc uccuucccac ucaacgcaca caugaaugca     1380

accaaccacg cgauugugca gaccuugguu caccuuauga accccgagua uguccccaaa     1440

ccgugcugug cgccaacuaa gcuaaaugcc aucucgguuc uuuacuuuga ugacaacucc     1500

aaugucauuc ugaaaaaaua caggaauaug guuguaagag cuuguggaug ccacuaagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  1425
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (wt)

<400>  1425
gggagaaagc uuaccaugca cgugcgcuca cugcgagcug cggcgccgca cagcuucgug       60

gcgcucuggg caccccuguu ccugcugcgc uccgcccugg ccgacuucag ccuggacaac      120

gaggugcacu cgagcuucau ccaccggcgc cuccgcagcc aggagcggcg ggagaugcag      180

cgcgagaucc ucuccauuuu gggcuugccc caccgcccgc gcccgcaccu ccagggcaag      240

cacaacucgg cacccauguu caugcuggac cuguacaacg ccauggcggu ggaggagggc      300

ggcgggcccg gcggccaggg cuucuccuac cccuacaagg ccgucuucag uacccagggc      360

cccccucugg ccagccugca agauagccau uuccucaccg acgccgacau ggucaugagc      420

uucgucaacc ucguggaaca ugacaaggaa uucuuccacc cacgcuacca ccaucgagag      480

uuccgguuug aucuuuccaa gaucccagaa ggggaagcug ucacggcagc cgaauuccgg      540

aucuacaagg acuacauccg ggaacgcuuc gacaaugaga cguuccggau cagcguuuau      600

caggugcucc aggagcacuu gggcagggaa ucggaucucu uccugcucga cagccguacc      660

cucugggccu cggaggaggg cuggcuggug uuugacauca cagccaccag caaccacugg      720

guggucaauc cgcggcacaa ccugggccug cagcucucgg uggagacgcu ggaugggcag      780

agcaucaacc ccaaguuggc gggccugauu gggcggcacg ggccccagaa caagcagccc      840

uucauggugg cuuucuucaa ggccacggag guccacuucc gcagcauccg guccacgggg      900

agcaaacagc gcagccagaa ccgcuccaag acgcccaaga accaggaagc ccugcggaug      960

gccaacgugg cagagaacag cagcagcgac cagaggcagg ccuguaagaa gcacgagcug     1020

uaugucagcu uccgagaccu gggcuggcag gacuggauca ucgcgccuga aggcuacgcc     1080

gccuacuacu gugaggggga gugugccuuc ccucugaacu ccuacaugaa cgccaccaac     1140

cacgccaucg ugcagacgcu gguccacuuc aucaacccgg aaacggugcc caagcccugc     1200

ugugcgccca cgcagcucaa ugccaucucc guccucuacu ucgaugacag cuccaacguc     1260

auccugaaga aauacagaaa cauggugguc cgggccugug gcugccacua gggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  1426
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (wt)

<400>  1426
gggagaaagc uuaccaugaa agccucugca gcacuucugu gucugcugcu cacagcagcu       60

gcuuucagcc cccaggggcu ugcucagcca guugggauua auacuucaac uaccugcugc      120

uacagauuua ucaauaagaa aaucccuaag cagaggcugg agagcuacag aaggaccacc      180

aguagccacu guccccggga agcuguaauc uucaagacca aacuggacaa ggagaucugu      240

gcugacccca cacagaagug gguccaggac uuuaugaagc accuggacaa gaaaacccaa      300

acuccaaagc uuugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  1427
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (wt)

<400>  1427
gggagaaagc uuaccaugcu gcucacucuu aucauucugu ugccaguagu uucaaaauuu       60

aguuuuguua gucucucagc accgcagcac uggagcuguc cugaagguac ucucgcagga      120

aaugggaauu cuacuugugu ggguccugca cccuucuuaa uuuucuccca uggaaauagu      180

aucuuuagga uugacacaga aggaaccaau uaugagcaau ugguggugga ugcugguguc      240

ucagugauca uggauuuuca uuauaaugag aaaagaaucu auugggugga uuuagaaaga      300

caacuuuugc aaagaguuuu ucugaauggg ucaaggcaag agagaguaug uaauauagag      360

aaaaauguuu cuggaauggc aauaaauugg auaaaugaag aaguuauuug gucaaaucaa      420

caggaaggaa ucauuacagu aacagauaug aaaggaaaua auucccacau ucuuuuaagu      480

gcuuuaaaau auccugcaaa uguagcaguu gauccaguag aaagguuuau auuuuggucu      540

ucagaggugg cuggaagccu uuauagagca gaucucgaug gugugggagu gaaggcucug      600

uuggagacau cagagaaaau aacagcugug ucauuggaug ugcuugauaa gcggcuguuu      660

uggauucagu acaacagaga aggaagcaau ucucuuauuu gcuccuguga uuaugaugga      720

gguucugucc acauuaguaa acauccaaca cagcauaauu uguuugcaau gucccuuuuu      780

ggugaccgua ucuucuauuc aacauggaaa augaagacaa uuuggauagc caacaaacac      840

acuggaaagg acaugguuag aauuaaccuc cauucaucau uuguaccacu uggugaacug      900

aaaguagugc auccacuugc acaacccaag gcagaagaug acacuuggga gccugagcag      960

aaacuuugca aauugaggaa aggaaacugc agcagcacug ugugugggca agaccuccag     1020

ucacacuugu gcaugugugc agagggauac gcccuaaguc gagaccggaa guacugugaa     1080

gauguuaaug aaugugcuuu uuggaaucau ggcuguacuc uuggguguaa aaacaccccu     1140

ggauccuauu acugcacgug cccuguagga uuuguucugc uuccugaugg gaaacgaugu     1200

caucaacuug uuuccugucc acgcaaugug ucugaaugca gccaugacug uguucugaca     1260

ucagaagguc ccuuauguuu cuguccugaa ggcucagugc uugagagaga ugggaaaaca     1320

uguagcgguu guuccucacc cgauaauggu ggauguagcc agcucugcgu uccucuuagc     1380

ccaguauccu gggaauguga uugcuuuccu ggguaugacc uacaacugga ugaaaaaagc     1440

ugugcagcuu caggaccaca accauuuuug cuguuugcca auucucaaga uauucgacac     1500

augcauuuug auggaacaga cuauggaacu cugcucagcc agcagauggg aaugguuuau     1560

gcccuagauc augacccugu ggaaaauaag auauacuuug cccauacagc ccugaagugg     1620

auagagagag cuaauaugga ugguucccag cgagaaaggc uuauugagga aggaguagau     1680

gugccagaag gucuugcugu ggacuggauu ggccguagau ucuauuggac agacagaggg     1740

aaaucucuga uuggaaggag ugauuuaaau gggaaacguu ccaaaauaau cacuaaggag     1800

aacaucucuc aaccacgagg aauugcuguu cauccaaugg ccaagagauu auucuggacu     1860

gauacaggga uuaauccacg aauugaaagu ucuucccucc aaggccuugg ccgucugguu     1920

auagccagcu cugaucuaau cuggcccagu ggaauaacga uugacuucuu aacugacaag     1980

uuguacuggu gcgaugccaa gcagucugug auugaaaugg ccaaucugga ugguucaaaa     2040

cgccgaagac uuacccagaa ugauguaggu cacccauuug cuguagcagu guuugaggau     2100

uauguguggu ucucagauug ggcuaugcca ucaguaauga gaguaaacaa gaggacuggc     2160

aaagauagag uacgucucca aggcagcaug cugaagcccu caucacuggu ugugguucau     2220

ccauuggcaa aaccaggagc agaucccugc uuauaucaaa acggaggcug ugaacauauu     2280

ugcaaaaaga ggcuuggaac ugcuuggugu ucgugucgug aagguuuuau gaaagccuca     2340

gaugggaaaa cgugucuggc ucuggauggu caucagcugu uggcaggugg ugaaguugau     2400

cuaaagaacc aaguaacacc auuggacauc uuguccaaga cuagaguguc agaagauaac     2460

auuacagaau cucaacacau gcuaguggcu gaaaucaugg ugucagauca agaugacugu     2520

gcuccugugg gaugcagcau guaugcucgg uguauuucag agggagagga ugccacaugu     2580

caguguuuga aaggauuugc uggggaugga aaacuauguu cugauauaga ugaaugugag     2640

augggugucc cagugugccc cccugccucc uccaagugca ucaacaccga aggugguuau     2700

gucugccggu gcucagaagg cuaccaagga gaugggauuc acugucuuga uauugaugag     2760

ugccaacugg gggagcacag cuguggagag aaugccagcu gcacaaauac agagggaggc     2820

uauaccugca ugugugcugg acgccugucu gaaccaggac ugauuugccc ugacucuacu     2880

ccacccccuc accucaggga agaugaccac cacuauuccg uaagaaauag ugacucugaa     2940

uguccccugu cccacgaugg guacugccuc caugauggug ugugcaugua uauugaagca     3000

uuggacaagu augcaugcaa cuguguuguu ggcuacaucg gggagcgaug ucaguaccga     3060

gaccugaagu ggugggaacu gcgccacgcu ggccacgggc agcagcagaa ggucaucgug     3120

guggcugucu gcgugguggu gcuugucaug cugcuccucc ugagccugug gggggcccac     3180

uacuacagga cucagaagcu gcuaucgaaa aacccaaaga auccuuauga ggagucgagc     3240

agagauguga ggagucgcag gccugcugac acugaggaug ggauguccuc uugcccucaa     3300

ccuugguuug ugguuauaaa agaacaccaa gaccucaaga auggggguca accaguggcu     3360

ggugaggaug gccaggcagc agauggguca augcaaccaa cuucauggag gcaggagccc     3420

caguuaugug gaaugggcac agagcaaggc ugcuggauuc caguauccag ugauaagggc     3480

uccugucccc agguaaugga gcgaagcuuu cauaugcccu ccuaugggac acagacccuu     3540

gaagggggug ucgagaagcc ccauucucuc cuaucagcua acccauuaug gcaacaaagg     3600

gcccuggacc caccacacca aauggagcug acucagugag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  1428
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (wt)

<400>  1428
gggagaaagc uuaccaugac cgcggggagg aggauggaga ugcucugugc cggcaggguc       60

ccugcgcugc ugcucugccu ggguuuccau cuucuacagg caguccucag uacaacugug      120

auuccaucau guaucccagg agaguccagu gauaacugca cagcuuuagu ucagacagaa      180

gacaauccac guguggcuca agugucaaua acaaagugua gcucugacau gaauggcuau      240

uguuugcaug gacagugcau cuaucuggug gacaugaguc aaaacuacug caggugugaa      300

guggguuaua cugguguccg augugaacac uucuuuuuaa ccguccacca accuuuaagc      360

aaagaauaug uggcuuugac cgugauucuu auuauuuugu uucuuaucac agucgucggu      420

uccacauauu auuucugcag augguacaga aaucgaaaaa guaaagaacc aaagaaggaa      480

uaugagagag uuaccucagg ggauccagag uugccgcaag ucugaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  1429
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (wt)

<400>  1429
gggagaaagc uuaccauggc ugaaggggaa aucaccaccu ucacagcccu gaccgagaag       60

uuuaaucugc cuccagggaa uuacaagaag cccaaacucc ucuacuguag caacgggggc      120

cacuuccuga ggauccuucc ggauggcaca guggauggga caagggacag gagcgaccag      180

cacauucagc ugcagcucag ugcggaaagc gugggggagg uguauauaaa gaguaccgag      240

acuggccagu acuuggccau ggacaccgac gggcuuuuau acggcucaca gacaccaaau      300

gaggaauguu uguuccugga aaggcuggag gagaaccauu acaacaccua uauauccaag      360

aagcaugcag agaagaauug guuuguuggc cucaagaaga augggagcug caaacgcggu      420

ccucggacuc acuauggcca gaaagcaauc uuguuucucc cccugccagu cucuucugau      480

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  1430
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (wt)

<400>  1430
gggagaaagc uuaccauggu gggugugggg gguggagaug uagaagaugu gacgccgcgg       60

cccggcgggu gccagauuag cggacgcggu gcccgcgguu gcaacgggau cccgggcgcu      120

gcagcuuggg aggcggcucu ccccaggcgg cguccgcgga gacacccauc cgugaacccc      180

aggucccggg ccgccggcuc gccgcgcacc aggggccggc ggacagaaga gcggccgagc      240

ggcucgaggc ugggggaccg cgggcgcggc cgcgcgcugc cgggcgggag gcuggggggc      300

cggggccggg gccgugcccc ggagcggguc ggaggccggg gccggggccg ggggacggcg      360

gcuccccgcg cggcuccagc ggcucgggga ucccggccgg gccccgcagg gaccauggca      420

gccgggagca ucaccacgcu gcccgccuug cccgaggaug gcggcagcgg cgccuucccg      480

cccggccacu ucaaggaccc caagcggcug uacugcaaaa acgggggcuu cuuccugcgc      540

auccaccccg acggccgagu ugacgggguc cgggagaaga gcgacccuca caucaagcua      600

caacuucaag cagaagagag aggaguugug ucuaucaaag gagugugugc uaaccguuac      660

cuggcuauga aggaagaugg aagauuacug gcuucuaaau guguuacgga ugaguguuuc      720

uuuuuugaac gauuggaauc uaauaacuac aauacuuacc ggucaaggaa auacaccagu      780

ugguaugugg cacugaaacg aacugggcag uauaaacuug gauccaaaac aggaccuggg      840

cagaaagcua uacuuuuucu uccaaugucu gcuaagagcu gaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  1431
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (wt)

<400>  1431
gggagaaagc uuaccaugca caaauggaua cugacaugga uccugccaac uuugcucuac       60

agaucaugcu uucacauuau cugucuagug gguacuauau cuuuagcuug caaugacaug      120

acuccagagc aaauggcuac aaaugugaac uguuccagcc cugagcgaca cacaagaagu      180

uaugauuaca uggaaggagg ggauauaaga gugagaagac ucuucugucg aacacagugg      240

uaccugagga ucgauaaaag aggcaaagua aaagggaccc aagagaugaa gaauaauuac      300

aauaucaugg aaaucaggac aguggcaguu ggaauugugg caaucaaagg gguggaaagu      360

gaauucuauc uugcaaugaa caaggaagga aaacucuaug caaagaaaga augcaaugaa      420

gauuguaacu ucaaagaacu aauucuggaa aaccauuaca acacauaugc aucagcuaaa      480

uggacacaca acggagggga aauguuuguu gccuuaaauc aaaaggggau uccuguaaga      540

ggaaaaaaaa cgaagaaaga acaaaaaaca gcccacuuuc uuccuauggc aauaacuuaa      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  1432
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (wt)

<400>  1432
gggagaaagc uuaccaugaa gcugcugccg ucgguggugc ugaagcucuu ucuggcugca       60

guucucucgg cacuggugac uggcgagagc cuggagcggc uucggagagg gcuagcugcu      120

ggaaccagca acccggaccc ucccacugua uccacggacc agcugcuacc ccuaggaggc      180

ggccgggacc ggaaaguccg ugacuugcaa gaggcagauc uggaccuuuu gagagucacu      240

uuauccucca agccacaagc acuggccaca ccaaacaagg aggagcacgg gaaaagaaag      300

aagaaaggca aggggcuagg gaagaagagg gacccauguc uucggaaaua caaggacuuc      360

ugcauccaug gagaaugcaa auaugugaag gagcuccggg cucccuccug caucugccac      420

ccggguuacc auggagagag gugucauggg cugagccucc caguggaaaa ucgcuuauau      480

accuaugacc acacaaccau ccuggccgug guggcugugg ugcugucauc ugucugucug      540

cuggucaucg uggggcuucu cauguuuagg uaccauagga gaggagguua ugauguggaa      600

aaugaagaga aagugaaguu gggcaugacu aauucccacu gaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  1433
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (wt)

<400>  1433
gggagaaagc uuaccaugug ggugaccaaa cuccugccag cccugcugcu gcagcauguc       60

cuccugcauc uccuccugcu ccccaucgcc auccccuaug cagagggaca aaggaaaaga      120

agaaauacaa uucaugaauu caaaaaauca gcaaagacua cccuaaucaa aauagaucca      180

gcacugaaga uaaaaaccaa aaaagugaau acugcagacc aaugugcuaa uagauguacu      240

aggaauaaag gacuuccauu cacuugcaag gcuuuuguuu uugauaaagc aagaaaacaa      300

ugccucuggu uccccuucaa uagcauguca aguggaguga aaaaagaauu uggccaugaa      360

uuugaccucu augaaaacaa agacuacauu agaaacugca ucauugguaa aggacgcagc      420

uacaagggaa caguaucuau cacuaagagu ggcaucaaau gucagcccug gaguuccaug      480

auaccacacg aacacagcuu uuugccuucg agcuaucggg guaaagaccu acaggaaaac      540

uacugucgaa auccucgagg ggaagaaggg ggacccuggu guuucacaag caauccagag      600

guacgcuacg aagucuguga cauuccucag uguucagaag uugaaugcau gaccugcaau      660

ggggagaguu aucgaggucu cauggaucau acagaaucag gcaagauuug ucagcgcugg      720

gaucaucaga caccacaccg gcacaaauuc uugccugaaa gauaucccga caagggcuuu      780

gaugauaauu auugccgcaa ucccgauggc cagccgaggc cauggugcua uacucuugac      840

ccucacaccc gcugggagua cugugcaauu aaaacaugcg cugacaauac uaugaaugac      900

acugauguuc cuuuggaaac aacugaaugc auccaagguc aaggagaagg cuacaggggc      960

acugucaaua ccauuuggaa uggaauucca ugucagcguu gggauucuca guauccucac     1020

gagcaugaca ugacuccuga aaauuucaag ugcaaggacc uacgagaaaa uuacugccga     1080

aauccagaug ggucugaauc acccuggugu uuuaccacug auccaaacau ccgaguuggc     1140

uacugcuccc aaauuccaaa cugugauaug ucacauggac aagauuguua ucgugggaau     1200

ggcaaaaauu auaugggcaa cuuaucccaa acaagaucug gacuaacaug uucaaugugg     1260

gacaagaaca uggaagacuu acaucgucau aucuucuggg aaccagaugc aaguaagcug     1320

aaugagaauu acugccgaaa uccagaugau gaugcucaug gacccuggug cuacacggga     1380

aauccacuca uuccuuggga uuauugcccu auuucucguu gugaagguga uaccacaccu     1440

acaauaguca auuuagacca ucccguaaua ucuugugcca aaacgaaaca auugcgaguu     1500

guaaauggga uuccaacacg aacaaacaua ggauggaugg uuaguuugag auacagaaau     1560

aaacauaucu gcggaggauc auugauaaag gagaguuggg uucuuacugc acgacagugu     1620

uucccuucuc gagacuugaa agauuaugaa gcuuggcuug gaauucauga uguccacgga     1680

agaggagaug agaaaugcaa acagguucuc aauguuuccc agcugguaua uggcccugaa     1740

ggaucagauc ugguuuuaau gaagcuugcc aggccugcug uccuggauga uuuuguuagu     1800

acgauugauu uaccuaauua uggaugcaca auuccugaaa agaccaguug caguguuuau     1860

ggcuggggcu acacuggauu gaucaacuau gauggccuau uacgaguggc acaucucuau     1920

auaaugggaa augagaaaug cagccagcau caucgaggga aggugacucu gaaugagucu     1980

gaaauaugug cuggggcuga aaagauugga ucaggaccau gugaggggga uuaugguggc     2040

ccacuuguuu gugagcaaca uaaaaugaga augguucuug gugucauugu uccuggucgu     2100

ggaugugcca uuccaaaucg uccugguauu uuuguccgag uagcauauua ugcaaaaugg     2160

auacacaaaa uuauuuuaac auauaaggua ccacagucau agggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  1434
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (wt)

<400>  1434
gggagaaagc uuaccauggc caaagccgcg gcgaucggca ucgaccuggg caccaccuac       60

uccugcgugg ggguguucca acacggcaag guggagauca ucgccaacga ccagggcaac      120

cgcaccaccc ccagcuacgu ggccuucacg gacaccgagc ggcucaucgg ggaugcggcc      180

aagaaccagg uggcgcugaa cccgcagaac accguguuug acgcgaagcg gcugauuggc      240

cgcaaguucg gcgacccggu ggugcagucg gacaugaagc acuggccuuu ccaggugauc      300

aacgacggag acaagcccaa ggugcaggug agcuacaagg gggagaccaa ggcauucuac      360

cccgaggaga ucucguccau ggugcugacc aagaugaagg agaucgccga ggcguaccug      420

ggcuacccgg ugaccaacgc ggugaucacc gugccggccu acuucaacga cucgcagcgc      480

caggccacca aggaugcggg ugugaucgcg gggcucaacg ugcugcggau caucaacgag      540

cccacggccg ccgccaucgc cuacggccug gacagaacgg gcaaggggga gcgcaacgug      600

cucaucuuug accugggcgg gggcaccuuc gacgugucca uccugacgau cgacgacggc      660

aucuucgagg ugaaggccac ggccggggac acccaccugg guggggagga cuuugacaac      720

aggcugguga accacuucgu ggaggaguuc aagagaaaac acaagaagga caucagccag      780

aacaagcgag ccgugaggcg gcugcgcacc gccugcgaga gggccaagag gacccugucg      840

uccagcaccc aggccagccu ggagaucgac ucccuguuug agggcaucga cuucuacacg      900

uccaucacca gggcgagguu cgaggagcug ugcuccgacc uguuccgaag cacccuggag      960

cccguggaga aggcucugcg cgacgccaag cuggacaagg cccagauuca cgaccugguc     1020

cuggucgggg gcuccacccg cauccccaag gugcagaagc ugcugcagga cuucuucaac     1080

gggcgcgacc ugaacaagag caucaacccc gacgaggcug uggccuacgg ggcggcggug     1140

caggcggcca uccugauggg ggacaagucc gagaacgugc aggaccugcu gcugcuggac     1200

guggcucccc ugucgcuggg gcuggagacg gccggaggcg ugaugacugc ccugaucaag     1260

cgcaacucca ccauccccac caagcagacg cagaucuuca ccaccuacuc cgacaaccaa     1320

cccggggugc ugauccaggu guacgagggc gagagggcca ugacgaaaga caacaaucug     1380

uuggggcgcu ucgagcugag cggcaucccu ccggccccca ggggcgugcc ccagaucgag     1440

gugaccuucg acaucgaugc caacggcauc cugaacguca cggccacgga caagagcacc     1500

ggcaaggcca acaagaucac caucaccaac gacaagggcc gccugagcaa ggaggagauc     1560

gagcgcaugg ugcaggaggc ggagaaguac aaagcggagg acgaggugca gcgcgagagg     1620

gugucagcca agaacgcccu ggaguccuac gccuucaaca ugaagagcgc cguggaggau     1680

gaggggcuca agggcaagau cagcgaggcg gacaagaaga aggugcugga caagugucaa     1740

gaggucaucu cguggcugga cgccaacacc uuggccgaga aggacgaguu ugagcacaag     1800

aggaaggagc uggagcaggu guguaacccc aucaucagcg gacuguacca gggugccggu     1860

ggucccgggc cugggggcuu cggggcucag ggucccaagg gagggucugg gucaggcccc     1920

accauugagg agguagauua gggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1435
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (wt)

<400>  1435
gggagaaagc uuaccauggc caaagccgcg gcgaucggca ucgaccuggg caccaccuac       60

uccugcgugg ggguguucca acacggcaag guggagauca ucgccaacga ccagggcaac      120

cgcaccaccc ccagcuacgu ggccuucacg gacaccgagc ggcucaucgg ggaugcggcc      180

aagaaccagg uggcgcugaa cccgcagaac accguguuug acgcgaagcg gcugauuggc      240

cgcaaguucg gcgacccggu ggugcagucg gacaugaagc acuggccuuu ccaggugauc      300

aacgacggag acaagcccaa ggugcaggug agcuacaagg gggagaccaa ggcauucuac      360

cccgaggaga ucucguccau ggugcugacc aagaugaagg agaucgccga ggcguaccug      420

ggcuacccgg ugaccaacgc ggugaucacc gugccggccu acuucaacga cucgcagcgc      480

caggccacca aggaugcggg ugugaucgcg gggcucaacg ugcugcggau caucaacgag      540

cccacggccg ccgccaucgc cuacggccug gacagaacgg gcaaggggga gcgcaacgug      600

cucaucuuug accugggcgg gggcaccuuc gacgugucca uccugacgau cgacgacggc      660

aucuucgagg ugaaggccac ggccggggac acccaccugg guggggagga cuuugacaac      720

aggcugguga accacuucgu ggaggaguuc aagagaaaac acaagaagga caucagccag      780

aacaagcgag ccgugaggcg gcugcgcacc gccugcgaga gggccaagag gacccugucg      840

uccagcaccc aggccagccu ggagaucgac ucccuguuug agggcaucga cuucuacacg      900

uccaucacca gggcgagguu cgaggagcug ugcuccgacc uguuccgaag cacccuggag      960

cccguggaga aggcucugcg cgacgccaag cuggacaagg cccagauuca cgaccugguc     1020

cuggucgggg gcuccacccg cauccccaag gugcagaagc ugcugcagga cuucuucaac     1080

gggcgcgacc ugaacaagag caucaacccc gacgaggcug uggccuacgg ggcggcggug     1140

caggcggcca uccugauggg ggacaagucc gagaacgugc aggaccugcu gcugcuggac     1200

guggcucccc ugucgcuggg gcuggagacg gccggaggcg ugaugacugc ccugaucaag     1260

cgcaacucca ccauccccac caagcagacg cagaucuuca ccaccuacuc cgacaaccaa     1320

cccggggugc ugauccaggu guacgagggc gagagggcca ugacgaaaga caacaaucug     1380

uuggggcgcu ucgagcugag cggcaucccu ccggccccca ggggcgugcc ccagaucgag     1440

gugaccuucg acaucgaugc caacggcauc cugaacguca cggccacgga caagagcacc     1500

ggcaaggcca acaagaucac caucaccaac gacaagggcc gccugagcaa ggaggagauc     1560

gagcgcaugg ugcaggaggc ggagaaguac aaagcggagg acgaggugca gcgcgagagg     1620

gugucagcca agaacgcccu ggaguccuac gccuucaaca ugaagagcgc cguggaggau     1680

gaggggcuca agggcaagau cagcgaggcg gacaagaaga agguucugga caagugucaa     1740

gaggucaucu cguggcugga cgccaacacc uuggccgaga aggacgaguu ugagcacaag     1800

aggaaggagc uggagcaggu guguaacccc aucaucagcg gacuguacca gggugccggu     1860

ggucccgggc cuggcggcuu cggggcucag ggucccaagg gagggucugg gucaggcccu     1920

accauugagg agguggauua gggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1436
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (wt)

<400>  1436
gggagaaagc uuaccauggc uacugccaag ggaaucgcca uaggcaucga ccugggcacc       60

accuacuccu gugugggggu guuccagcac ggcaaggugg agaucaucgc caacgaccag      120

ggcaaccgca ccacccccag cuacguggcc uucacagaca ccgagcggcu cauuggggau      180

gcggccaaga accagguagc aaugaauccc cagaacacug uuuuugaugc uaaacgucug      240

aucggcagga aauuuaauga uccuguugua caagcagaua ugaaacuuug gccuuuucaa      300

gugauuaaug aaggaggcaa gcccaaaguc cuuguguccu acaaagggga gaauaaagcu      360

uucuacccug aggaaaucuc uucgauggua uugacuaagu ugaaggagac ugcugaggcc      420

uuuuugggcc acccugucac caaugcagug auuaccgugc cagccuauuu caaugacucu      480

caacgucagg cuacuaagga ugcaggugug auugcuggac uuaaugugcu aagaaucauc      540

aaugagccca cggcugcugc cauugccuau gguuuagaua aaggagguca aggagaacga      600

cauguccuga uuuuugaucu ggguggaggc acauuugaug ugucaauucu gaccauagau      660

gaugggauuu uugagguaaa ggccacugcu ggggacacuc accugggugg ggaggacuuu      720

gacaacaggc uugugagcca cuucguggag gaguucaaga ggaaacacaa aaaggacauc      780

agccagaaca agcgagccgu gaggcggcug cgcaccgccu gcgagagggc caagaggacc      840

cugucgucca gcacccaggc caaccuagaa auugauucac uuuaugaagg cauugacuuc      900

uauacaucca ucaccagagc ucgauuugaa gaguugugug cagaccuguu uagggguacc      960

cuggagccug uagaaaaagc gcuucgggau gccaagaugg auaaggcuaa aauccaugac     1020

auuguuuuag uagggggcuc cacccgcauc cccaaggugc agcggcugcu ucaggacuac     1080

uucaauggac gugaucucaa caagagcauc aacccugaug aggccguagc auauggggcu     1140

gcgguacaag cagccauccu gaugggggac aagucugaga agguacagga ccugcugcug     1200

cuggacgugg cuccccuguc ccuggggcug gagacggcug ggggcgugau gacugcccug     1260

auaaagcgca acuccaccau ccccaccaag cagacacaga uuuucaccac cuacucugac     1320

aaccaacccg gggugcugau ccagguguau gagggcgaga gggccaugac aaaggacaac     1380

aaccugcugg ggcgguuuga ccugacugga aucccuccag cacccagggg aguuccucag     1440

aucgagguga cguuugacau ugaugccaau gguauucuca augucacagc cacggacaag     1500

agcaccggca aggugaacaa gaucaccauc accaaugaca agggccgccu gagcaaggag     1560

gagauugagc gcaugguucu ggaugcugag aaauauaaag cugaagauga gguccagagg     1620

gagaaaauug cugcaaagaa ugccuuagaa uccuaugcuu uuaacaugaa gaguguugug     1680

agugaugaag guuugaaggg caagauuagu gagucugaua aaaauaaaau auuggauaaa     1740

ugcaacgagc uccuuucgug gcuggagguc aaucaacugg cagagaaaga ugaguuugau     1800

cauaagagaa aggaauugga gcagaugugu aacccuauca ucacaaaacu cuaccaagga     1860

ggaugcacug ggccugccug cggaacaggg uaugugccug gaaggccugc cacaggcccc     1920

acaauugaag aaguagauua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1437
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (wt)

<400>  1437
gggagaaagc uuaccauguc ugcccguggc ccggcuaucg gcaucgaccu gggcaccacc       60

uauucgugcg ucggggucuu ccaacauggc aagguggaga ucaucgccaa cgaccagggc      120

aaucgcacca cccccagcua cguggccuuc acggacaccg agcgccucau cggcgacgcc      180

gccaagaacc agguggccau gaaccccacc aacaccaucu ucgacgccaa gaggcugauu      240

ggacggaaau ucgaggaugc cacagugcag ucggauauga aacacuggcc guuccgggug      300

gugagcgagg gaggcaagcc caaagugcaa guagaguaca agggggagac caagaccuuc      360

uucccagagg agauauccuc caugguccuc acgaagauga aggagaucgc ggaagccuac      420

cuggggggca aggugcacag cgcggucaua acggucccgg ccuauuucaa cgacucgcag      480

cgccaggcca ccaaggacgc aggcaccauc acggggcuca augugcugcg caucaucaac      540

gagcccacgg cggcggccau cgccuacggc cuggacaaga agggcugcgc gggcggcgag      600

aagaacgugc ucaucuuuga ccugggcggu ggcacuuucg acguguccau ccugaccauc      660

gaggauggca ucuucgaggu gaaguccacg gccggcgaca cccaccuggg cggugaggac      720

uucgacaacc gcauggugag ccaccuggcg gaggaguuca agcgcaagca caagaaggac      780

auugggccca acaagcgcgc cgugaggcgg cugcgcaccg cuugcgagcg cgccaagcgc      840

acccugagcu cguccacgca ggcgagcauc gagaucgacu cgcucuacga gggcguggac      900

uucuauacgu ccaucacgcg cgcccgcuuc gaggagcuca augccgaccu cuuucgcggg      960

acccuggagc cgguggagaa ggcgcugcgc gacgccaagc uggacaaggg ccagauccag     1020

gagaucgugc uggugggcgg cuccacucgu auccccaaga uccagaagcu gcugcaggau     1080

uucuucaacg gcaaggagcu gaacaagagc aucaaccccg acgaggcggu ggccuauggc     1140

gccgcggugc aggcggccau ccucaucggc gacaaaucag agaaugugca ggaccugcug     1200

cuacucgacg ugaccccguu gucgcugggc aucgagacag cuggcggugu caugacccca     1260

cucaucaaga ggaacaccac gauccccacc aagcagacgc agaccuucac caccuacucg     1320

gacaaccaga gcagcguacu ggugcaggua uacgagggcg aacgggccau gaccaaggac     1380

aauaaccugc ugggcaaguu cgaccugacc gggauucccc cugcgccucg cggggucccc     1440

caaaucgagg uuaccuucga cauugacgcc aauggcaucc uuaacguuac cgccgccgac     1500

aagagcaccg guaaggaaaa caaaaucacc aucaccaaug acaaaggucg ucugagcaag     1560

gacgacauug accggauggu gcaggaggcg gagcgguaca aaucggaaga ugaggcgaau     1620

cgcgaccgag ucgcggccaa aaacgcccug gaguccuaua ccuacaacau caagcagacg     1680

guggaagacg agaaacugag gggcaagauu agcgagcagg acaaaaacaa gauccucgac     1740

aagugucagg aggugaucaa cuggcucgac cgaaaccaga uggcagagaa agaugaguau     1800

gaacacaagc agaaagagcu cgaaagaguu ugcaacccca ucaucagcaa acuuuaccaa     1860

ggugguccug gcggcggcag cggcggcggc gguucaggag ccuccggggg acccaccauc     1920

gaagaagugg acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  1438
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (wt)

<400>  1438
gggagaaagc uuaccauguc gguggugggc auagaccugg gcuuccagag cugcuacguc       60

gcuguggccc gcgccggcgg caucgagacu aucgcuaaug aguauagcga ccgcugcacg      120

ccggcuugca uuucuuuugg uccuaagaau cguucaauug gagcagcagc uaaaagccag      180

guaauuucua augcaaagaa cacaguccaa ggauuuaaaa gauuccaugg ccgagcauuc      240

ucugauccau uuguggaggc agaaaaaucu aaccuugcau augauauugu gcaguugccu      300

acaggauuaa cagguauaaa ggugacauau auggaggaag agcgaaauuu uaccacugag      360

caagugacug ccaugcuuuu guccaaacug aaggagacag ccgaaagugu ucuuaagaag      420

ccuguaguug acuguguugu uucgguuccu uguuucuaua cugaugcaga aagacgauca      480

gugauggaug caacacagau ugcuggucuu aauugcuugc gauuaaugaa ugaaaccacu      540

gcaguugcuc uugcauaugg aaucuauaag caggaucuuc cugccuuaga agagaaacca      600

agaaauguag uuuuuguaga caugggccac ucugcuuauc aaguuucugu augugcauuu      660

aauagaggaa aacugaaagu ucuggccacu gcauuugaca cgacauuggg agguagaaaa      720

uuugaugaag uguuaguaaa ucacuucugu gaagaauuug ggaagaaaua caagcuagac      780

auuaagucca aaauccgugc auuauuacga cucucucagg agugugagaa acucaagaaa      840

uugaugagug caaaugcuuc agaucucccu uugagcauug aauguuuuau gaaugauguu      900

gauguaucug gaacuaugaa uagaggcaaa uuucuggaga ugugcaauga ucucuuagcu      960

agaguggagc caccacuucg uaguguuuug gaacaaacca aguuaaagaa agaagauauu     1020

uaugcagugg agauaguugg uggugcuaca cgaaucccug cgguaaaaga gaagaucagc     1080

aaauuuuucg guaaagaacu uaguacaaca uuaaaugcug augaagcugu cacucgaggc     1140

ugugcauugc agugugccau cuuaucgccu gcuuucaaag ucagagaauu uucuaucacu     1200

gauguaguac cauauccaau aucucugaga uggaauucuc cagcugaaga agggucaagu     1260

gacugugaag ucuuuuccaa aaaucaugcu gcuccuuucu cuaaaguucu uacauuuuau     1320

agaaaggaac cuuucacucu ugaggccuac uacagcucuc cucaggauuu gcccuaucca     1380

gauccugcua uagcucaguu uucaguucag aaagucacuc cucagucuga uggcuccagu     1440

ucaaaaguga aagucaaagu ucgaguaaau guccauggca uuuucagugu guccagugca     1500

ucuuuagugg agguucacaa gucugaggaa aaugaggagc caauggaaac agaucagaau     1560

gcaaaggagg aagagaagau gcaaguggac caggaggaac cacauguuga agagcaacag     1620

cagcagacac cagcagaaaa uaaggcagag ucugaagaaa uggagaccuc ucaagcugga     1680

uccaaggaua aaaagaugga ccaaccaccc caagccaaga aggcaaaagu gaagaccagu     1740

acuguggacc ugccaaucga gaaucagcua uuauggcaga uagacagaga gaugcucaac     1800

uuguacauug aaaaugaggg uaagaugauc augcaggaua aacuggagaa ggagcggaau     1860

gaugcuaaga acgcagugga ggaauaugug uaugaaauga gagacaagcu uaguggugaa     1920

uaugagaagu uugugaguga agaugaucgu aacaguuuua cuuugaaacu ggaagauacu     1980

gaaaauuggu uguaugagga uggagaagac cagccaaagc aaguuuaugu ugauaaguug     2040

gcugaauuaa aaaaucuagg ucaaccuauu aagauacguu uccaggaauc ugaagaacga     2100

ccaaaauuau uugaagaacu agggaaacag auccaacagu auaugaaaau aaucagcucu     2160

uucaaaaaca aggaggacca guaugaucau uuggaugcug cugacaugac aaagguagaa     2220

aaaagcacaa augaagcaau ggaguggaug aauaacaagc uaaaucugca gaacaagcag     2280

aguuugacca uggauccagu ugucaaguca aaagagauug aagcuaaaau uaaggagcug     2340

acaaguacuu guagcccuau aauuucaaag cccaaaccca aaguggaacc uccaaaagag     2400

gaacaaaaaa augcagagca gaauggacca guggauggac aaggagacaa cccaggcccc     2460

caggcugcug agcaggguac agacacagcu gugccuucgg auucagacaa gaagcuuccu     2520

gaaauggaca uugauugagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  1439
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (wt)

<400>  1439
gggagaaagc uuaccauguc ugugguuggc auugaccucg gcuuucucaa cugcuacauu       60

gcugucgcga gaaguggcgg caucgagacc aucgccaaug aguacagcga cagguguacc      120

ccggccugua uaucauuggg aucaagaacu cgagccauug gaaaugcagc aaagagccag      180

auagucacga acguaagaaa uacaauucau ggcuucaaaa agcuucaugg gcgaucauuu      240

gaugauccca uugugcaaac ugaaaggauc aggcuucccu augaacugca gaaaaugccu      300

aauggaagug caggaguuaa ggugcgguac uuagaggaag agagaccuuu ugcaauugag      360

caaguuacug gaaugcuguu agccaagcuu aaagagacuu cagaaaaugc uuugaagaaa      420

ccaguggcug acugugugau uucaauuccu agcuuuuuua cugaugccga gagaagaucu      480

gugauggcug cagcccaggu ugcaggcuua aauuguuuaa gguugaugaa ugaaacuacu      540

gcaguugcac uggcguaugg aauuuauaaa caggaucuuc ccccauuaga ugagaaacca      600

agaaauguag uauuuauuga uaugggacau ucugccuauc aggucuuggu uugugcuuuu      660

aacaaaggaa aacuuaaagu cuuggcuacu accuuugauc cauauuuggg uggcaggaac      720

uuugaugagg cuuuaguaga cuacuucugu gaugaguuca agaccaaaua uaagauaaau      780

gugaaagaaa acucucgggc cuuguugcgu uuauaucagg aaugugaaaa acuaaagaag      840

cuaaugagug caaaugcauc agaucuucca uugaacauug aguguuucau gaaugaccuu      900

gauguuucua guaaaaugaa cagggcucaa uuugaacaac ugugugcuuc ccuuuuggcc      960

aggguugaac caccuuuaaa agcaguaaug gaacaagcua acuuacaacg ugaagacauu     1020

aguaguauag aaauuguagg aggagcaaca cgaauuccug cagugaaaga acaaaucacu     1080

aaauucuuuc uuaaagacau aaguaccaca uuaaaugcug augaagcugu ugcaagagga     1140

ugugcguuac agugugcgau ucucucacca gcauuuaaag ugcgugaauu uuccauaaca     1200

gaccuuguuc ccuauucaau cacauuaagg uggaagaccu cuuuugaaga uggaaguggg     1260

gaaugugaag uuuucuguaa gaaccauccu gccccauucu caaaagucau uacuuuccac     1320

aagaaggaac cauuugaacu agaagcauuu uauacuaauu uacaugaagu gccuuauccu     1380

gaugcaagaa uugggagcuu cacuauucag aauguuuuuc cacagucuga uggugauagu     1440

uccaaaguga agguuaaagu ucguguuaac auccauggaa ucuucagugu ggcuagcgca     1500

ucaguaauug agaagcaaaa uuuggaaggc gaucacagug augcuccaau ggagacagaa     1560

acuucauuua aaaaugaaaa caaagauaau auggauaaaa ugcagguuga ucaagaagaa     1620

gggcaucaaa aaugucaugc ugaacacacu ccagaagagg aaauugauca uacaggagcc     1680

aaaacaaagu cagcugucuc agacaaacaa gaccgauuaa aucagacacu uaaaaaagga     1740

aaagucaaaa guauugaucu accgauccag aguagccuau guagacaacu aggccaagau     1800

cuucucaaca gcuacauuga aaaugagggg aagaugauca ugcaagauaa guuagagaaa     1860

gaaagaaaug augcuaagaa ugccguugaa gaauauguau augauuuuag agacaggcug     1920

ggcacugucu augaaaaauu caucacucca gaagacuuga guaaacuguc ugcaguauug     1980

gaagacacag aaaauuggcu uuaugaagac ggagaggacc aaccuaaaca aguuuaugug     2040

gauaagcuuc aagaacuaaa gaaauacggc cagccuauuc aaaugaagua cauggagcau     2100

gaagagagac caaaagccuu aaaugacuug ggaaaaaaga uccaacuugu caugaaagug     2160

auagaagcuu auagaaacaa ggaugaaaga uaugaucauc uggauccuac ugaaauggaa     2220

aagguugaaa aauguaucag ugaugccaug aguuggcuga auaguaagau gaaugcacag     2280

aacaaacuaa gucucacuca agauccugug guaaaaguuu cagaaauagu agcaaaguca     2340

aaggaacugg auaauuucug uaaccccauc auuuacaagc ccaaaccaaa agcagaaguu     2400

ccugaagaca aaccaaaagc uaauagugaa cacaauggcc caauggaugg acagagugga     2460

acugaaacua aaucagauuc aacaaaagac agcucacagc auacuaaauc cucuggagag     2520

auggaagugg acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  1440
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (wt)

<400>  1440
gggagaaagc uuaccaugaa gcucucccug guggccgcga ugcugcugcu gcucagcgcg       60

gcgcgggccg aggaggagga caagaaggag gacgugggca cgguggucgg caucgaccug      120

gggaccaccu acuccugcgu cggcguguuc aagaacggcc gcguggagau caucgccaac      180

gaucagggca accgcaucac gccguccuau gucgccuuca cuccugaagg ggaacgucug      240

auuggcgaug ccgccaagaa ccagcucacc uccaaccccg agaacacggu cuuugacgcc      300

aagcggcuca ucggccgcac guggaaugac ccgucugugc agcaggacau caaguucuug      360

ccguucaagg ugguugaaaa gaaaacuaaa ccauacauuc aaguugauau uggagguggg      420

caaacaaaga cauuugcucc ugaagaaauu ucugccaugg uucucacuaa aaugaaagaa      480

accgcugagg cuuauuuggg aaagaagguu acccaugcag uuguuacugu accagccuau      540

uuuaaugaug cccaacgcca agcaaccaaa gacgcuggaa cuauugcugg ccuaaauguu      600

augaggauca ucaacgagcc uacggcagcu gcuauugcuu auggccugga uaagagggag      660

ggggagaaga acauccuggu guuugaccug gguggcggaa ccuucgaugu gucucuucuc      720

accauugaca auggugucuu cgaaguugug gccacuaaug gagauacuca ucugggugga      780

gaagacuuug accagcgugu cauggaacac uucaucaaac uguacaaaaa gaagacgggc      840

aaagauguca ggaaagacaa uagagcugug cagaaacucc ggcgcgaggu agaaaaggcc      900

aaacgggccc ugucuucuca gcaucaagca agaauugaaa uugaguccuu cuaugaagga      960

gaagacuuuu cugagacccu gacucgggcc aaauuugaag agcucaacau ggaucuguuc     1020

cggucuacua ugaagcccgu ccagaaagug uuggaagauu cugauuugaa gaagucugau     1080

auugaugaaa uuguucuugu ugguggcucg acucgaauuc caaagauuca gcaacugguu     1140

aaagaguucu ucaauggcaa ggaaccaucc cguggcauaa acccagauga agcuguagcg     1200

uauggugcug cuguccaggc uggugugcuc ucuggugauc aagauacagg ugaccuggua     1260

cugcuugaug uauguccccu uacacuuggu auugaaacug ugggaggugu caugaccaaa     1320

cugauuccaa ggaacacagu ggugccuacc aagaagucuc agaucuuuuc uacagcuucu     1380

gauaaucaac caacuguuac aaucaagguc uaugaaggug aaagaccccu gacaaaagac     1440

aaucaucuuc uggguacauu ugaucugacu ggaauuccuc cugcuccucg ugggguccca     1500

cagauugaag ucaccuuuga gauagaugug aaugguauuc uucgagugac agcugaagac     1560

aaggguacag ggaacaaaaa uaagaucaca aucaccaaug accagaaucg ccugacaccu     1620

gaagaaaucg aaaggauggu uaaugaugcu gagaaguuug cugaggaaga caaaaagcuc     1680

aaggagcgca uugauacuag aaaugaguug gaaagcuaug ccuauucucu aaagaaucag     1740

auuggagaua aagaaaagcu gggagguaaa cuuuccucug aagauaagga gaccauggaa     1800

aaagcuguag aagaaaagau ugaauggcug gaaagccacc aagaugcuga cauugaagac     1860

uucaaagcua agaagaagga acuggaagaa auuguucaac caauuaucag caaacucuau     1920

ggaagugcag gcccuccccc aacuggugaa gaggauacag cagaaaaaga ugaguuguag     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  1441
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (wt)

<400>  1441
gggagaaagc uuaccaugca ggccccacgg gagcucgcgg ugggcaucga ccugggcacc       60

accuacucgu gcgugggcgu guuucagcag ggccgcgugg agauccuggc caacgaccag      120

ggcaaccgca ccacgcccag cuacguggcc uucaccgaca ccgagcggcu ggucggggac      180

gcggccaaga gccaggcggc ccugaacccc cacaacaccg uguucgaugc caagcggcug      240

aucgggcgca aguucgcgga caccacggug cagucggaca ugaagcacug gcccuuccgg      300

guggugagcg agggcggcaa gcccaaggug cgcguaugcu accgcgggga ggacaagacg      360

uucuaccccg aggagaucuc guccauggug cugagcaaga ugaaggagac ggccgaggcg      420

uaccugggcc agcccgugaa gcacgcagug aucaccgugc ccgccuauuu caaugacucg      480

cagcgccagg ccaccaagga cgcgggggcc aucgcggggc ucaacguguu gcggaucauc      540

aaugagccca cggcagcugc caucgccuau gggcuggacc ggcggggcgc gggagagcgc      600

aacgugcuca uuuuugaccu gggugggggc accuucgaug ugucgguucu cuccauugac      660

gcuggugucu uugaggugaa agccacugcu ggagauaccc accugggagg agaggacuuc      720

gacaaccggc ucgugaacca cuucauggaa gaauuccggc ggaagcaugg gaaggaccug      780

agcgggaaca agcgugcccu gcgcaggcug cgcacagccu gugagcgcgc caagcgcacc      840

cuguccucca gcacccaggc cacccuggag auagacuccc uguucgaggg cguggacuuc      900

uacacgucca ucacucgugc ccgcuuugag gaacugugcu cagaccucuu ccgcagcacc      960

cuggagccgg uggagaaggc ccugcgggau gccaagcugg acaaggccca gauucaugac     1020

gucguccugg uggggggcuc cacacgcauc cccaaggugc agaaguugcu gcaggacuuc     1080

uucaacggca aggagcugaa caagagcauc aacccugaug aggcuguggc cuauggggcu     1140

gcugugcagg cggccguguu gaugggggac aaaugugaga aagugcagga ucuccugcug     1200

cuggaugugg cuccccuguc ucuggggcug gagacagcag guggggugau gaccacgcug     1260

auccagagga acgccacuau ccccaccaag cagacccaga cuuucaccac cuacucggac     1320

aaccagccug gggucuucau ccagguguau gagggugaga gggccaugac caaggacaac     1380

aaccugcugg ggcguuuuga acucaguggc aucccuccug ccccacgugg agucccccag     1440

auagagguga cuuuugacau ugaugcuaau ggcauccuga gcgugacagc cacugacagg     1500

agcacaggua aggcuaacaa gaucaccauc accaaugaca agggccggcu gagcaaggag     1560

gagguggaga ggaugguuca ugaagccgag caguacaagg cugaggauga ggcccagagg     1620

gacagagugg cugccaaaaa cucgcuggag gcccaugucu uccaugugaa agguucuuug     1680

caagaggaaa gccuuaggga caagauuccc gaagaggaca ggcgcaaaau gcaagacaag     1740

ugucgggaag uccuugccug gcuggagcac aaccagcugg cagagaagga ggaguaugag     1800

caucagaaga gggagcugga gcaaaucugu cgccccaucu ucuccaggcu cuaugggggg     1860

ccuggugucc cugggggcag caguuguggc acucaagccc gccaggggga ccccagcacc     1920

ggccccauca uugaggaggu ugauugagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  1442
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (wt)

<400>  1442
gggagaaagc uuaccaugca ggccccacgg gagcucgcgg ugggcaucga ccugggcacc       60

accuacucgu gcgugggcgu guuucagcag ggccgcgugg agauccuggc caacgaccag      120

ggcaaccgca ccacgcccag cuacguggcc uucaccgaca ccgagcggcu ggucggggac      180

gcggccaaga gccaggcggc ccugaacccc cacaacaccg uguucgaugc caagcggcug      240

aucgggcgca aguucgcgga caccacggug cagucggaca ugaagcacug gcccuuccag      300

guggugagcg agggcggcaa gcccaaggug cgcguaugcu accgcgggga ggacaagacg      360

uucuaccccg aggagaucuc guccauggug cugagcaaga ugaaggagac ggccgaggcg      420

uaccugggcc agcccgugaa gcacgcagug aucaccgugc ccaccuauuu caguaacucg      480

cagcgccagg ccaccaagga cgcgggggcc aucgcggggc ucaaggugcu gccgaucauc      540

aaugaggcca cggcagcagc caucgccuau gggcuggacc ggcggggcgc gggaaagcgc      600

aacgugcuca uuuuugaccu gggugggggc accuucgaug ugucgguucu cuccauugac      660

gccggugucu uugaggugaa agccacugcu ggagauaccc accugggagg agaggacuuc      720

gacaaccggc ucgugaacca cuucauggaa gaauuccggc ggaagcaugg gaaggaccug      780

agcgggaaca agcgugcccu gcgcaggcug cgcacagccu gugagcgcgc caagcgcacc      840

ccguccucca gcacccaggc cacccuggag auagacuccc uguucgaggg cguggacuuc      900

uacaagucca ucacucgugc ccgcuuugag gaacugugcu cagaccucuu ccgcagcacc      960

cuggagccgg uggagaaggc ccugcgggau gccaagcugg acaaggccca gauucaugac     1020

uucguccugg ggggagggcu ccacucgcau ccccaaggug cagaaguugc ugcaggacuu     1080

cuucaacggc aaggagcuga acaagagcau caacccugag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  1443
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (wt)

<400>  1443
gggagaaagc uuaccauguc caagggaccu gcaguuggua uugaucuugg caccaccuac       60

ucuugugugg guguuuucca gcacggaaaa gucgagauaa uugccaauga ucagggaaac      120

cgaaccacuc caagcuaugu cgccuuuacg gacacugaac gguugaucgg ugaugccgca      180

aagaaucaag uugcaaugaa ccccaccaac acaguuuuug augccaaacg ucugauugga      240

cgcagauuug augaugcugu uguccagucu gauaugaaac auuggcccuu uaugguggug      300

aaugaugcug gcaggcccaa gguccaagua gaauacaagg gagagaccaa aagcuucuau      360

ccagaggagg ugucuucuau gguucugaca aagaugaagg aaauugcaga agccuaccuu      420

gggaagacug uuaccaaugc uguggucaca gugccagcuu acuuuaauga cucucagcgu      480

caggcuacca aagaugcugg aacuauugcu ggucucaaug uacuuagaau uauuaaugag      540

ccaacugcug cugcuauugc uuacggcuua gacaaaaagg uuggagcaga aagaaacgug      600

cucaucuuug accugggagg uggcacuuuu gaugugucaa uccucacuau ugaggaugga      660

aucuuugagg ucaagucuac agcuggagac acccacuugg guggagaaga uuuugacaac      720

cgaaugguca accauuuuau ugcugaguuu aagcgcaagc auaagaagga caucagugag      780

aacaagagag cuguaagacg ccuccguacu gcuugugaac gugcuaagcg uacccucucu      840

uccagcaccc aggccaguau ugagaucgau ucucucuaug aaggaaucga cuucuauacc      900

uccauuaccc gugcccgauu ugaagaacug aaugcugacc uguuccgugg cacccuggac      960

ccaguagaga aagcccuucg agaugccaaa cuagacaagu cacagauuca ugauauuguc     1020

cugguuggug guucuacucg uauccccaag auucagaagc uucuccaaga cuucuucaau     1080

ggaaaagaac ugaauaagag caucaacccu gaugaagcug uugcuuaugg ugcagcuguc     1140

caggcagcca ucuugucugg agacaagucu gagaauguuc aagauuugcu gcucuuggau     1200

gucacuccuc uuucccuugg uauugaaacu gcugguggag ucaugacugu ccucaucaag     1260

cguaauacca ccauuccuac caagcagaca cagaccuuca cuaccuauuc ugacaaccag     1320

ccuggugugc uuauucaggu uuaugaaggc gagcgugcca ugacaaagga uaacaaccug     1380

cuuggcaagu uugaacucac aggcauaccu ccugcacccc gagguguucc ucagauugaa     1440

gucacuuuug acauugaugc caaugguaua cucaaugucu cugcugugga caagaguacg     1500

ggaaaagaga acaagauuac uaucacuaau gacaagggcc guuugagcaa ggaagacauu     1560

gaacguaugg uccaggaagc ugagaaguac aaagcugaag augagaagca gagggacaag     1620

gugucaucca agaauucacu ugaguccuau gccuucaaca ugaaagcaac uguugaagau     1680

gagaaacuuc aaggcaagau uaacgaugag gacaaacaga agauucugga caaguguaau     1740

gaaauuauca acuggcuuga uaagaaucag acugcugaga aggaagaauu ugaacaucaa     1800

cagaaagagc uggagaaagu uugcaacccc aucaucacca agcuguacca gagugcagga     1860

ggcaugccag gaggaaugcc ugggggauuu ccugguggug gagcuccucc cucugguggu     1920

gcuuccucag ggcccaccau ugaagagguu gauuaaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  1444
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (wt)

<400>  1444
gggagaaagc uuaccaugau aagugccagc cgagcugcag cagcccgucu cgugggcgcc       60

gcagccuccc ggggcccuac ggccgcccgc caccaggaua gcuggaaugg ccuuagucau      120

gaggcuuuua gacuuguuuc aaggcgggau uaugcaucag aagcaaucaa gggagcaguu      180

guugguauug auuuggguac uaccaacucc ugcguggcag uuauggaagg uaaacaagca      240

aaggugcugg agaaugccga aggugccaga accaccccuu caguuguggc cuuuacagca      300

gauggugagc gacuuguugg aaugccggcc aagcgacagg cugucaccaa cccaaacaau      360

acauuuuaug cuaccaagcg ucucauuggc cggcgauaug augauccuga aguacagaaa      420

gacauuaaaa auguucccuu uaaaauuguc cgugccucca auggugaugc cuggguugag      480

gcucauggga aauuguauuc uccgagucag auuggagcau uuguguugau gaagaugaaa      540

gagacugcag aaaauuacuu ggggcacaca gcaaaaaaug cugugaucac agucccagcu      600

uauuucaaug acucgcagag acaggccacu aaagaugcug gccagauauc uggacugaau      660

gugcuucggg ugauuaauga gcccacagcu gcugcucuug ccuauggucu agacaaauca      720

gaagacaaag ucauugcugu auaugauuua ggugguggaa cuuuugauau uucuauccug      780

gaaauucaga aaggaguauu ugaggugaaa uccacaaaug gggauaccuu cuuagguggg      840

gaagacuuug accaggccuu gcuacggcac auugugaagg aguucaagag agagacaggg      900

guugauuuga cuaaagacaa cauggcacuu cagaggguac gggaagcugc ugaaaaggcu      960

aaaugugaac ucuccucauc ugugcagacu gacaucaauu ugcccuaucu uacaauggau     1020

ucuucuggac ccaagcauuu gaauaugaag uugacccgug cucaauuuga agggauuguc     1080

acugaucuaa ucagaaggac uaucgcucca ugccaaaaag cuaugcaaga ugcagaaguc     1140

agcaagagug acauaggaga agugauucuu guggguggca ugacuaggau gcccaagguu     1200

cagcagacug uacaggaucu uuuuggcaga gccccaagua aagcugucaa uccugaugag     1260

gcuguggcca uuggagcugc cauucaggga gguguguugg ccggcgaugu cacggaugug     1320

cugcuccuug augucacucc ccugucucug gguauugaaa cucuaggagg ugucuuuacc     1380

aaacuuauua auaggaauac cacuauucca accaagaaga gccagguauu cucuacugcc     1440

gcugaugguc aaacgcaagu ggaaauuaaa gugugucagg gugaaagaga gauggcugga     1500

gacaacaaac uccuuggaca guuuacuuug auuggaauuc caccagcccc ucguggaguu     1560

ccucagauug aaguuacauu ugacauugau gccaauggga uaguacaugu uucugcuaaa     1620

gauaaaggca caggacguga gcagcagauu guaauccagu cuucuggugg auuaagcaaa     1680

gaugauauug aaaauauggu uaaaaaugca gagaaauaug cugaagaaga ccggcgaaag     1740

aaggaacgag uugaagcagu uaauauggcu gaaggaauca uucacgacac agaaaccaag     1800

auggaagaau ucaaggacca auuaccugcu gaugagugca acaagcugaa agaagagauu     1860

uccaaaauga gggagcuccu ggcuagaaaa gacagcgaaa caggagaaaa uauuagacag     1920

gcagcauccu cucuucagca ggcaucacug aagcuguucg aaauggcaua caaaaagaug     1980

gcaucugagc gagaaggcuc uggaaguucu ggcacugggg aacaaaagga agaucaaaag     2040

gaggaaaaac aguaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  1445
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (wt)

<400>  1445
gggagaaagc uuaccauggc ggacaaggag gccggcggca gcgacgggcc ccgagaaacg       60

gcucccacau cugcauauuc aucuccagcc cggagucuug gggacacagg aauaacgccu      120

cugucccccu cccauauugu gaacgacacu gacuccaacg ucucagaaca gcagucauuu      180

cucguggugg uggccgucga cuuugggacc acauccagug gcuaugccua cagcuucacc      240

aaggagccgg aaugcaucca ugugaugagg cgaugggagg gaggugaccc uggugugucc      300

aaucagaaga cuccaaccac caucuugcug acucccgaga ggaaguucca cagcuucggg      360

uaugccgcca gggacuuuua ccaugaccug gaucccaaug aggccaagca guggcuguac      420

cuggagaagu ucaagaugaa gcugcacacc acuggggacc ucaccaugga uacagaccug      480

acggcagcaa auggcaagaa agucaaagcc cuugaaaucu uugcuuaugc ccugcaguac      540

uuuaaggagc aggcgcugaa ggagcugagu gaccaggcgg guucggaguu cgagaacucu      600

gaugucagau gggucaucac ggugccugcc aucuggaagc agccggccaa gcaguucaug      660

agacaagcug ccuaccaggc aggccuggcc ucccccgaga acucggagca gcucaucauu      720

gccuuggagc cugaggcagc cucuaucuac ugccgaaagc ugcggcuaca ccagaugauu      780

gagcugagca gcaaggcagc cgucaauggg uacagcggca gugacacagu aggagcuggg      840

uuuacacagg cuaaggaaca cauacggcgu aaucggcaga gucggaccuu uuugguggag      900

aaugucauag gagaaaucug guccgagcug gaggaaggug auaaguaugu gguuguggac      960

aguggcggug gcaccguaga ccugacaguc caucagaucc gguuaccgga gggacaccuu     1020

aaggaacugu auaaagcaac aggcggaccc uauggaucuu uaggaguaga uuaugaguuc     1080

gaaaaacuuc uguauaaaau auuuggagag gauuuuauug aacaauucaa aaucaaacgc     1140

ccugcagccu ggguugacuu aaugauugcg uuugagucuc gcaaaagggc ggcugcccca     1200

gacagaacua acccgcugaa caucacccug cccuucuccu ucauugacua cuacaagaag     1260

uuccgcgggc acagugugga gcacgccuug cggaaaagca auguggauuu ugugaagugg     1320

uccucgcagg ggaugcugcg gaugagucca gaugccauga acgcccuuuu uaagccgacc     1380

aucgauagca ucauugagca ucuccgggac cuguuucaga agcccgaggu guccaccguc     1440

aaguuccucu uucugguggg cggcuuugcc gaggcgcccc ugcugcagca ggcggugcag     1500

gcugcuuuug gggaccagug ccggaucauc aucccccagg acgugggccu caccauccuc     1560

aagggugccg uccucuuugg ccuggacccc gcggucauca aggugcgccg gucgccgcuc     1620

accuacgggg uaggcgugcu gaaccgcuac guggagggca agcacccgcc ugagaagcug     1680

cuggugaagg auggcacucg guggugcacc gacgucuuug acaaguucau cucugccgac     1740

cagucugugg cucuggguga gcuggucaag cguagcuaca ccccggccaa gcccucccag     1800

cuggucauug ucaucaacau cuacagcucu gagcacgaca acgucagcuu caucacugau     1860

cccgggguga agaagugugg cacgcuccgc cuggaucuca cagggaccag uggcacugcg     1920

gugcccgccc ggagggagau ccagacccuu augcaguucg gggacaccga gaucaaagcc     1980

acagccauug auauagccac uucgaagagu gucaaaguug ggaucgacuu cuuaaauuac     2040

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  1446
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (wt)

<400>  1446
gggagaaagc uuaccauguu ggcugucccg gagaugggcc ugcaggggcu guacaucggc       60

uccagcccgg agcggucccc agugccuagc ccacccggcu ccccgaggac ccaggaaagc      120

ugcggcauug ccccccucac acccucgcag ucuccaaaac ccgagguccg agccccccag      180

caggccuccu ucucuguggu gguggccauu gacuucggca ccacgucuag uggcuaugcu      240

uucagcuuug ccagugaccc ugaggccauc cacaugauga ggaaauggga gggcggagac      300

ccgggcgugg cccaccagaa gaccccgacc ugccugcugc ugacuccgga gggcgccuuc      360

cacagcuuug gcuacaccgc ccgcgauuac uaccaugacc uggaccccga agaggcgcgg      420

gacuggcucu acuucgagaa guucaagaug aagauccaca gcgccacgga ucucaccuug      480

aagacccagc uagaggcagu aaauggaaag acgaugcccg cccuggaggu guucgcccau      540

gcccugcgcu ucuucaggga gcacgcccuu caggagcuga gggagcagag cccaucgcug      600

ccagagaagg acacugugcg cuggguguug acggugccug ccaucuggaa acagccagcc      660

aagcaguuca ugcgggaggc ugccuaccug gcuggacuag ugucccgaga gaaugcagag      720

cagcuacuca ucgcccugga gcccgaggcc gccucgguau acugccgcaa gcugcgccug      780

caccagcucc uggaccugag uggccgggcc ccagguggug ggcgccuggg ugagcgccgc      840

uccaucgacu ccagcuuccg ucaggcucgg gagcagcugc gaaggucccg ccacagccgc      900

acguuccugg uggagucagg cguaggagag cugugggcag agaugcaagc aggagaccgc      960

uacguggugg ccgacugcgg cggaggcacc guggaccuga cggugcacca gcuggagcag     1020

ccccauggca cccucaagga gcucuacaag gcaucugggg gcccuuaugg cgcggugggc     1080

guggaccugg ccuucgagca gcugcugugc cgcaucuucg gcgaggacuu caucgccacc     1140

uucaaaaggc aacggccggc agccugggua gaucugacca ucgccuucga ggcucgcaag     1200

cgcacugcug gcccacaccg ugcaggggcg cucaacaucu cgcugcccuu cuccuucauu     1260

gacuucuacc gcaagcagcg gggccacaac guggagaccg cucugcgcag gagcagcgug     1320

aacuucguga agugguccuc acaggggaug cuccgaaugu cuugugaagc caugaacgag     1380

cucuuucagc ccaccgucag cgggaucauc cagcacauag aggcccugcu ggcacggccg     1440

gaggugcagg gugugaagcu gcuguuccua gugggcggcu ucgccgaguc agcggugcug     1500

cagcacgcgg ugcaggcggc gcugggcgcc cgcggucugc gugucguggu cccgcacgac     1560

gugggccuca ccauccucaa aggcgcggug cuguucggcc aggcgccggg cguggugcgg     1620

guccgccgcu cgccgcucac cuauggcgug ggcgugcuca accgcuuugu gccugggcgc     1680

cacccgcccg aaaagcugcu gguucgcgac ggccgccgcu ggugcaccga cgucuucgag     1740

cgcuucgugg ccgccgagca gucgguggcc cugggcgagg aggugcggcg cagcuacugc     1800

ccggcgcguc ccggccagcg gcgcguacuc aucaaccugu acugcugcgc ggcagaggau     1860

gcgcgcuuca ucaccgaccc cggcgugcgc aaaugcggcg cgcucagccu cgagcuugag     1920

cccgccgacu gcggccagga caccgccggc gcgccucccg gccgccgcga gauccgcgcc     1980

gccaugcagu uuggcgacac cgaaauuaag gucaccgccg ucgacgucag caccaaucgc     2040

uccgugcgcg cguccaucga cuuucuuucc aacugaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  1447
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (wt)

<400>  1447
gggagaaagc uuaccauggc cagagagaug acgaucuuag gaucggcugu uuugacucuc       60

cuguuggccg gcuauuuggc acaacaguau uuaccauugc cuacuccuaa agugauuggu      120

auugaucuug gcaccaccua uuguucuguu gggguguuuu uuccuggcac aggaaaagua      180

aaggugauuc cagaugaaaa ugggcauauc agcauaccca gcaugguguc uuuuacugac      240

aaugauguau augugggaua ugaaagcgua gagcuggcag auucaaaucc ucaaaacaca      300

auauaugaug ccaaaagauu cauaggcaag auuuuuaccg cagaagaguu ggaggcugaa      360

auuggcagau acccauuuaa gguuuuaaac aaaaauggaa ugguugaguu uucugugaca      420

aguaaugaga ccaucacagu guccccagaa uauguuggcu cucgacuauu guugaaguua      480

aaggaaaugg cagaggcaua ucuuggaaug ccaguugcca augcugucau uucuguacca      540

gcagaauuug aucuaaaaca gagaaauuca acaauugaag cugcuaaccu ugcaggacug      600

aagauuuuga ggguaauaaa ugaacccaca gcagcagcua uggccuaugg ucuccacaag      660

gcugacgucu uccacgucuu ggugauagac uugggcggag gaacucuaga ugugucuuua      720

cugaauaaac aaggagggau guuucuaacc cgagcaaugu cuggaaacaa uaaacuugga      780

ggacaggacu ucaaucagag auugcuucag uacuuauaua aacagaucua ucaaacauau      840

ggcuucgugc ccucuaggaa agaggaaauc cacagauuga gacaagcugu ggaaaugguc      900

aaauuaaauc ugacucuuca ucaaucugcu caguugucag uauuacuaac gguggaggag      960

caggacagga aggaaccuca caguagugac acugaacugc caaaagacaa acuuuccuca     1020

gcagaugacc aucgcgugaa caguggguuu ggacguggcc uuucugauaa gaaaagugga     1080

gaaagucagg uuuuauuuga aacagaaaua ucacggaaac ucuuugauac ccuuaaugaa     1140

gaccucuuuc agaaaauacu gguacccauu cagcaaguau ugaaagaagg ccaccuggaa     1200

aagacugaga uugaugaggu gguuuuaguu gggggcucca cucguauucc ucggauccgu     1260

caagucauuc aagaguucuu uggaaaagau cccaacacau cuguagaccc ugaccuagca     1320

guaguaacgg gaguggcuau ccaagcaggg auugauggag gcucuuggcc ucuccaaguc     1380

agugcuuuag aaauucccaa uaagcauuua caaaaaacca acuucaacug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  1448
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (wt)

<400>  1448
gggagaaagc uuaccauggc ggccaucgga guucaccugg gcugcaccuc agccugugug       60

gccgucuaua aggauggccg ggcuggugug guugcaaaug augccgguga ccgaguuacu      120

ccagcuguug uugcuuacuc agaaaaugaa gagauuguug gauuggcagc aaaacaaagu      180

agaauaagaa auauuucaaa uacaguaaug aaaguaaagc agauccuggg cagaagcucc      240

agugauccac aagcucagaa auacaucgcg gaaaguaaau guuuagucau ugaaaaaaau      300

gggaaauuac gauaugaaau agauacugga gaagaaacaa aauuuguuaa cccagaagau      360

guugccagac ugauauuuag uaaaaugaaa gaaacggcac auucuguauu gggcucagau      420

gcaaaugaug uaguuauuac ugucccguuu gauuuuggag aaaagcaaaa aaaugcucuu      480

ggagaagcag cuagagcugc uggauuuaau guuuugcgau uaauucacga accgucugca      540

gcucuucuug cuuauggaau uggacaagac uccccuacug gaaaaagcaa uauuuuggug      600

uuuaagcuug gaggaacauc cuuaucucuc agcgucaugg aaguuaacag uggaauauau      660

cggguucuuu caacaaacac ugaugauaac aucgguggug cacauuucac agaaaccuua      720

gcacaguauc uagcuucuga guuccaaaga uccuucaaac augaugugag aggaaaugcg      780

cgagccauga ugaaauuaac gaacagugcu gaaguagcga aacauucuuu gucaaccuug      840

ggaagugcca acuguuuucu ugacucauua uaugaagguc aagauuuuga uugcaaugug      900

uccagagcaa gauuugaacu ucuuuguucu ccacuuuuua auaaguguau agaagcaauc      960

agaggacucu uagaucaaaa uggauuuaca gcagaugaua ucaacaaggu uguccuuugu     1020

ggagggucuu cucgaauccc aaagcuacag caacugauua aagaucuuuu cccagcuguu     1080

gagcuucuca auucuauccc uccugaugaa gugaucccua uuggugcagc uauagaagca     1140

ggaauucuua uugggaaaga aaaccuguug guggaagacu cucuuaugau agaguguuca     1200

gccagagaua uuuuaguuaa ggguguggac gaaucaggag ccaguagauu cacagugcug     1260

uuuccaucag ggacuccuuu gccagcucga agacaacaca cauugcaagc cccuggaagc     1320

auaucuucag ugugccuuga acucuaugag ucugauggga agaacucugc caaagaggaa     1380

accaaguuug cacagguugu acuccaggau uuagauaaaa aagaaaaugg auuacgugau     1440

auauuagcug uucuuacuau gaaaagggau ggaucuuuac augugacaug cacagaucaa     1500

gaaacuggaa aaugugaagc aaucucuauu gagauagcau cuuagggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  1449
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (wt)

<400>  1449
gggagaaagc uuaccauguc gguggugggg uuggacgugg gcucgcagag cugcuacauc       60

gcgguagccc gggccggggg caucgagacc aucgccaaug aguucagcga ccggugcacc      120

ccgucaguca uaucauuugg aucaaaaaau agaacaaucg gaguugcagc caaaaaucag      180

caaaucacuc augcaaacaa uacggugucu aacuucaaaa gauuucaugg ccgagcauuc      240

aaugaccccu ucauucaaaa ggagaaggaa aacuugaguu acgauuuggu uccauugaaa      300

aaugguggag uuggaauaaa gguaauguac augggugaag aacaucuauu uaguguggag      360

cagauaacag ccauguuguu gacuaagcug aaggaaacug cugaaaacag ccucaagaaa      420

ccaguaacag auuguguuau uucagucccc uccuucuuua cagaugcuga gaggcgaucu      480

guguuagaug cugcacagau uguuggccua aacuguuuaa gacuuaugaa ugacaugaca      540

gcuguugcuu ugaauuacgg aauuuauaag caggaucucc caagccugga ugagaaaccu      600

cggauagugg uuuuuguuga uaugggacau ucagcuuuuc aagugucugc uugugcuuuu      660

aacaagggaa aauugaaggu acugggaaca gcuuuugauc cuuucuuagg aggaaaaaac      720

uucgaugaaa aguuagugga acauuuuugu gcagaauuua aaacuaagua caaguuggau      780

gcaaaaucca aaauacgagc acuccuacgu cuguaucagg aaugugaaaa acugaaaaag      840

cuaaugagcu cuaacagcac agaccuucca cugaauaucg aaugcuuuau gaaugauaaa      900

gauguuuccg gaaagaugaa caggucacaa uuugaagaac ucugugcuga acuucugcaa      960

aagauagaag uaccccuuua uucacuguug gaacaaacuc aucucaaagu agaagaugug     1020

agugcaguug agauuguugg aggcgcuaca cgaauuccag cugugaagga aagaauugcc     1080

aaauucuuug gaaaagauau uagcacaaca cucaaugcag augaagcagu agccagagga     1140

ugugcauuac agugugcaau acuuuccccg gcauuuaaag uuagagaauu uuccgucaca     1200

gaugcaguuc cuuuuccaau aucucugauc uggaaccaug auucagaaga uacugaaggu     1260

guucaugaag ucuuuagucg aaaccaugcu gcuccuuucu ccaaaguucu caccuuucug     1320

agaagggggc cuuuugagcu agaagcuuuc uauucugauc cccaaggagu uccauaucca     1380

gaagcaaaaa uaggccgcuu uguaguucag aauguuucug cacagaaaga uggagaaaaa     1440

ucuagaguaa aagucaaagu gcgagucaac acccauggca uuuucaccau cucuacggca     1500

ucuauggugg agaaaguccc aacugaggag aaugaaaugu cuucugaagc ugacauggag     1560

ugucugaauc agagaccacc agaaaaccca gacacugaua aaaaugucca gcaagacaac     1620

agugaagcug gaacacagcc ccagguacaa acugaugcuc aacaaaccuc acagucuccc     1680

ccuucaccug aacuuaccuc agaagaaaac aaaaucccag augcugacaa agcaaaugaa     1740

aaaaaaguug accagccucc agaagcuaaa aagcccaaaa uaaagguggu gaauguugag     1800

cugccuauug aagccaacuu ggucuggcag uuagggaaag accuucuuaa cauguauauu     1860

gagacagagg guaagaugau aaugcaagau aaauuggaaa aagaaaggaa ugaugcuaaa     1920

aaugcaguug aggaauaugu guaugaguuc agagacaagc uguguggacc auaugaaaaa     1980

uuuauaugug agcaggauca ucaaaauuuu uugagacucc ucacagaaac ugaagacugg     2040

cuguaugaag aaggagagga ccaagcuaaa caagcauaug uugacaaguu ggaagaauua     2100

augaaaauug gcacuccagu uaaaguucgg uuucaggaag cugaagaacg gccaaaaaug     2160

uuugaagaac uaggacagag gcugcagcau uaugccaaga uagcagcuga cuucagaaau     2220

aaggaugaga aauacaacca uauugaugag ucugaaauga aaaaagugga gaagucuguu     2280

aaugaaguga uggaauggau gaauaauguc augaaugcuc aggcuaaaaa gagucuugau     2340

caggauccag uuguacgugc ucaggaaauu aaaacaaaaa ucaaggaauu gaacaacaca     2400

ugugaacccg uuguaacaca accgaaacca aaaauugaau cacccaaacu ggaaagaacu     2460

ccaaauggcc caaauauuga uaaaaaggaa gaagauuuag aagacaaaaa caauuuuggu     2520

gcugaaccuc cacaucagaa uggugaaugu uacccuaaug agaaaaauuc uguuaauaug     2580

gacuuggacu agggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  1450
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (wt)

<400>  1450
gggagaaagc uuaccauggc agacaaaguu aggaggcaga ggccgaggag gcgagucugu       60

ugggccuugg uggcugugcu cuuggcagac cuguuggcac ugagugauac acuggcagug      120

augucugugg accugggcag ugaguccaug aagguggcca uugucaaacc uggagugccc      180

auggaaauug ucuugaauaa ggaaucucgg aggaaaacac cggugaucgu gacccugaaa      240

gaaaaugaaa gauucuuugg agacagugca gcaagcaugg cgauuaagaa uccaaaggcu      300

acgcuacguu acuuccagca ccuccugggg aagcaggcag auaaccccca uguagcucuu      360

uaccaggccc gcuucccgga gcacgagcug acuuucgacc cacagaggca gacugugcac      420

uuucagauca gcucgcagcu gcaguucuca ccugaggaag uguugggcau gguucucaau      480

uauucucguu cucuagcuga agauuuugca gagcagccca ucaaggaugc agugaucacc      540

gugccagucu ucuucaacca ggccgagcgc cgagcugugc ugcaggcugc ucguauggcu      600

ggccucaaag ugcugcagcu caucaaugac aacaccgcca cugcccucag cuaugguguc      660

uuccgccgga aagauauuaa caccacugcc cagaauauca uguucuauga caugggcuca      720

ggcagcaccg uaugcaccau ugugaccuac cagaugguga agacuaagga agcugggaug      780

cagccacagc ugcagauccg gggaguagga uuugaccgua cccugggggg ccuggagaug      840

gagcuccggc uucgagaacg ccuggcuggg cuuuucaaug agcagcgcaa gggucagaga      900

gcaaaggaug ugcgggagaa cccgcgugcc auggccaagc ugcugcguga ggcuaaucgg      960

cucaaaaccg uccucagugc caacgcugac cacauggcac agauugaagg ccugauggau     1020

gauguggacu ucaaggcaaa agugacucgu guggaauuug aggaguugug ugcagacuug     1080

uuugagcggg ugccugggcc uguacagcag gcccuccaga gugccgaaau gagucuggau     1140

gagauugagc aggugauccu gguggguggg gccacucggg uccccagagu ucaggaggug     1200

cugcugaagg ccgugggcaa ggaggagcug gggaagaaca ucaaugcaga ugaagcagcc     1260

gccauggggg caguguacca ggcagcugcg cucagcaaag ccuuuaaagu gaagccauuu     1320

gucguccgag augcaguggu cuaccccauc cugguggagu ucacgaggga gguggaggag     1380

gagccuggga uucacagccu gaagcacaau aaacggguac ucuucucucg gauggggccc     1440

uacccucaac gcaaagucau caccuuuaac cgcuacagcc augauuucaa cuuccacauc     1500

aacuacggcg accugggcuu ccuggggccu gaagaucuuc ggguauuugg cucccagaau     1560

cugaccacag ugaagcuaaa aggggugggu gacagcuuca agaaguaucc ugacuacgag     1620

uccaagggca ucaaggcuca cuucaaccug gaugagagug gcgugcucag ucuagacagg     1680

guggagucug uauuugagac acugguagag gacagcgcag aagaggaauc uacucucacc     1740

aaacuuggca acaccauuuc cagccuguuu ggaggcggua ccacaccaga ugccaaggag     1800

aaugguacug auacugucca ggaggaagag gagagcccug cagaggggag caaggacgag     1860

ccuggggagc agguggagcu caaggaggaa gcugaggccc caguggagga uggcucucag     1920

cccccacccc cugaaccuaa gggagaugca accccugagg gagaaaaggc cacagaaaaa     1980

gaaaaugggg acaagucuga ggcccagaaa ccaagugaga aggcagaggc agggccugag     2040

ggcgucgcuc cagccccaga gggagagaag aagcagaagc ccgccaggaa gcggcgaaug     2100

guagaggaga ucggggugga gcugguuguu cuggaccugc cugacuugcc agaggauaag     2160

cuggcucagu cggugcagaa acuucaggac uugacacucc gagaccugga gaagcaggaa     2220

cgggaaaaag cugccaacag cuuggaagca uucauauuug agacccagga caagcuguac     2280

cagcccgagu accaggaagu guccacagag gagcagcgug aggagaucuc ugggaagcuc     2340

agcgccgcau ccaccuggcu ggaggaugag gguguuggag ccaccacagu gauguugaag     2400

gagaagcugg cugagcugag gaagcugugc caagggcugu uuuuucgggu agaggagcgc     2460

aagaaguggc ccgaacggcu gucugcccuc gauaaucucc ucaaccauuc cagcauguuc     2520

cucaaggggg cccggcucau cccagagaug gaccagaucu ucacugaggu ggagaugaca     2580

acguuagaga aagucaucaa ugagaccugg gccuggaaga augcaacucu ggccgagcag     2640

gcuaagcugc ccgccacaga gaagccugug uugcucucaa aagacauuga agcuaagaug     2700

auggcccugg accgagaggu gcaguaucug cucaauaagg ccaaguuuac caagccccgg     2760

ccccggccua aggacaagaa ugggacccgg gcagagccac cccucaaugc cagugccagu     2820

gaccaggggg agaaggucau cccuccagca ggccagacug aagaugcaga gcccauuuca     2880

gaaccugaga aaguagagac uggauccgag ccaggagaca cugagccuuu ggaguuagga     2940

gguccuggag cagaaccuga acagaaagaa caaucgacag gacagaagcg gccuuugaag     3000

aacgacgaac uauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1451
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (wt)

<400>  1451
gggagaaagc uuaccaugcc ugaggaaacc cagacccaag accaaccgau ggaggaggag       60

gagguugaga cguucgccuu ucaggcagaa auugcccagu ugaugucauu gaucaucaau      120

acuuucuacu cgaacaaaga gaucuuucug agagagcuca uuucaaauuc aucagaugca      180

uuggacaaaa uccgguauga aagcuugaca gaucccagua aauuagacuc ugggaaagag      240

cugcauauua accuuauacc gaacaaacaa gaucgaacuc ucacuauugu ggauacugga      300

auuggaauga ccaaggcuga cuugaucaau aaccuuggua cuaucgccaa gucugggacc      360

aaagcguuca uggaagcuuu gcaggcuggu gcagauaucu cuaugauugg ccaguucggu      420

guugguuuuu auucugcuua uuugguugcu gagaaaguaa cugugaucac caaacauaac      480

gaugaugagc aguacgcuug ggaguccuca gcagggggau cauucacagu gaggacagac      540

acaggugaac cuaugggucg uggaacaaaa guuauccuac accugaaaga agaccaaacu      600

gaguacuugg aggaacgaag aauaaaggag auugugaaga aacauucuca guuuauugga      660

uaucccauua cucuuuuugu ggagaaggaa cgugauaaag aaguaagcga ugaugaggcu      720

gaagaaaagg aagacaaaga agaagaaaaa gaaaaagaag agaaagaguc ggaagacaaa      780

ccugaaauug aagauguugg uucugaugag gaagaagaaa agaaggaugg ugacaagaag      840

aagaagaaga agauuaagga aaaguacauc gaucaagaag agcucaacaa aacaaagccc      900

aucuggacca gaaaucccga cgauauuacu aaugaggagu acggagaauu cuauaagagc      960

uugaccaaug acugggaaga ucacuuggca gugaagcauu uuucaguuga aggacaguug     1020

gaauucagag cccuucuauu ugucccacga cgugcuccuu uugaucuguu ugaaaacaga     1080

aagaaaaaga acaacaucaa auuguaugua cgcagaguuu ucaucaugga uaacugugag     1140

gagcuaaucc cugaauaucu gaacuucauu agaggggugg uagacucgga ggaucucccu     1200

cuaaacauau cccgugagau guugcaacaa agcaaaauuu ugaaaguuau caggaagaau     1260

uuggucaaaa aaugcuuaga acucuuuacu gaacuggcgg aagauaaaga gaacuacaag     1320

aaauucuaug agcaguucuc uaaaaacaua aagcuuggaa uacacgaaga cucucaaaau     1380

cggaagaagc uuucagagcu guuaagguac uacacaucug ccucugguga ugagaugguu     1440

ucucucaagg acuacugcac cagaaugaag gagaaccaga aacauaucua uuauaucaca     1500

ggugagacca aggaccaggu agcuaacuca gccuuugugg aacgucuucg gaaacauggc     1560

uuagaaguga ucuauaugau ugagcccauu gaugaguacu guguccaaca gcugaaggaa     1620

uuugagggga agacuuuagu gucagucacc aaagaaggcc uggaacuucc agaggaugaa     1680

gaagagaaaa agaagcagga agagaaaaaa acaaaguuug agaaccucug caaaaucaug     1740

aaagacauau uggagaaaaa aguugaaaag gugguugugu caaaccgauu ggugacaucu     1800

ccaugcugua uugucacaag cacauauggc uggacagcaa acauggagag aaucaugaaa     1860

gcucaagccc uaagagacaa cucaacaaug gguuacaugg cagcaaagaa acaccuggag     1920

auaaacccug accauuccau uauugagacc uuaaggcaaa aggcagaggc ugauaagaac     1980

gacaagucug ugaaggaucu ggucaucuug cuuuaugaaa cugcgcuccu gucuucuggc     2040

uucagucugg aagaucccca gacacaugcu aacaggaucu acaggaugau caaacuuggu     2100

cuggguauug augaagauga cccuacugcu gaugauacca gugcugcugu aacugaagaa     2160

augccacccc uugaaggaga ugacgacaca ucacgcaugg aagaaguaga cuaaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  1452
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (wt)

<400>  1452
gggagaaagc uuaccaugga uuccaguaaa uuagacucug ggaaagggcu gcauauuaac       60

cuuguaccaa acaaacaaaa ucaaacccuc acuauugugg acacuagaau uggaaugacc      120

aagacugacu ugaucaauaa ccucgguacu gucaccaagu cugggaccaa agcauucaug      180

gaagcuuugc aggcugaugc agauaucucu augauuggcc auuucggggu ugguuuuuau      240

ucugcuuauu ugguugccaa gaaaguaacu gugaucagca aacauaacaa ugaugagcag      300

uacaccuggg aguccucagc agggggauca uucacaguga ggacagacga gugaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  1453
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (wt)

<400>  1453
gggagaaagc uuaccaugcc ugaggaagug caccauggag aggaggaggu ggagacuuuu       60

gccuuucagg cagaaauugc ccaacucaug ucccucauca ucaauaccuu cuauuccaac      120

aaggagauuu uccuucggga guugaucucu aaugcuucug augccuugga caagauucgc      180

uaugagagcc ugacagaccc uucgaaguug gacaguggua aagagcugaa aauugacauc      240

auccccaacc cucaggaacg uacccugacu uugguagaca caggcauugg caugaccaaa      300

gcugaucuca uaaauaauuu gggaaccauu gccaagucug guacuaaagc auucauggag      360

gcucuucagg cuggugcaga caucuccaug auugggcagu uugguguugg cuuuuauucu      420

gccuacuugg uggcagagaa agugguugug aucacaaagc acaacgauga ugaacaguau      480

gcuugggagu cuucugcugg agguuccuuc acugugcgug cugaccaugg ugagcccauu      540

ggcaggggua ccaaagugau ccuccaucuu aaagaagauc agacagagua ccuagaagag      600

aggcggguca aagaaguagu gaagaagcau ucucaguuca uaggcuaucc caucacccuu      660

uauuuggaga aggaacgaga gaaggaaauu agugaugaug aggcagagga agagaaaggu      720

gagaaagaag aggaagauaa agaugaugaa gaaaaaccca agaucgaaga uguggguuca      780

gaugaggagg augacagcgg uaaggauaag aagaagaaaa cuaagaagau caaagagaaa      840

uacauugauc aggaagaacu aaacaagacc aagccuauuu ggaccagaaa cccugaugac      900

aucacccaag aggaguaugg agaauucuac aagagccuca cuaaugacug ggaagaccac      960

uuggcaguca agcacuuuuc uguagaaggu caguuggaau ucagggcauu gcuauuuauu     1020

ccucgucggg cucccuuuga ccuuuuugag aacaagaaga aaaagaacaa caucaaacuc     1080

uauguccgcc guguguucau cauggacagc ugugaugagu ugauaccaga guaucucaau     1140

uuuauccgug gugugguuga cucugaggau cugccccuga acaucucccg agaaaugcuc     1200

cagcagagca aaaucuugaa agucauucgc aaaaacauug uuaagaagug ccuugagcuc     1260

uucucugagc uggcagaaga caaggagaau uacaagaaau ucuaugaggc auucucuaaa     1320

aaucucaagc uuggaaucca cgaagacucc acuaaccgcc gccgccuguc ugagcugcug     1380

cgcuaucaua ccucccaguc uggagaugag augacaucuc ugucagagua uguuucucgc     1440

augaaggaga cacagaaguc caucuauuac aucacuggug agagcaaaga gcagguggcc     1500

aacucagcuu uuguggagcg agugcggaaa cggggcuucg aggugguaua uaugaccgag     1560

cccauugacg aguacugugu gcagcagcuc aaggaauuug augggaagag ccuggucuca     1620

guuaccaagg agggucugga gcugccugag gaugaggagg agaagaagaa gauggaagag     1680

agcaaggcaa aguuugagaa ccucugcaag cucaugaaag aaaucuuaga uaagaagguu     1740

gagaagguga caaucuccaa uagacuugug ucuucaccuu gcugcauugu gaccagcacc     1800

uacggcugga cagccaauau ggagcggauc augaaagccc aggcacuucg ggacaacucc     1860

accaugggcu auaugauggc caaaaagcac cuggagauca acccugacca ccccauugug     1920

gagacgcugc ggcagaaggc ugaggccgac aagaaugaua aggcaguuaa ggaccuggug     1980

gugcugcugu uugaaaccgc ccugcuaucu ucuggcuuuu cccuugagga uccccagacc     2040

cacuccaacc gcaucuaucg caugaucaag cuaggucuag guauugauga agaugaagug     2100

gcagcagagg aacccaaugc ugcaguuccu gaugagaucc ccccucucga gggcgaugag     2160

gaugcgucuc gcauggaaga agucgauuag ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  1454
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (wt)

<400>  1454
gggagaaagc uuaccaugag ggcccugugg gugcugggcc ucugcugcgu ccugcugacc       60

uucgggucgg ucagagcuga cgaugaaguu gauguggaug guacaguaga agaggaucug      120

gguaaaagua gagaaggauc aaggacggau gaugaaguag uacagagaga ggaagaagcu      180

auucaguugg auggauuaaa ugcaucacaa auaagagaac uuagagagaa gucggaaaag      240

uuugccuucc aagccgaagu uaacagaaug augaaacuua ucaucaauuc auuguauaaa      300

aauaaagaga uuuuccugag agaacugauu ucaaaugcuu cugaugcuuu agauaagaua      360

aggcuaauau cacugacuga ugaaaaugcu cuuucuggaa augaggaacu aacagucaaa      420

auuaagugug auaaggagaa gaaccugcug caugucacag acaccggugu aggaaugacc      480

agagaagagu ugguuaaaaa ccuugguacc auagccaaau cugggacaag cgaguuuuua      540

aacaaaauga cugaagcaca ggaagauggc cagucaacuu cugaauugau uggccaguuu      600

ggugucgguu ucuauuccgc cuuccuugua gcagauaagg uuauugucac uucaaaacac      660

aacaacgaua cccagcacau cugggagucu gacuccaaug aauuuucugu aauugcugac      720

ccaagaggaa acacucuagg acggggaacg acaauuaccc uugucuuaaa agaagaagca      780

ucugauuacc uugaauugga uacaauuaaa aaucucguca aaaaauauuc acaguucaua      840

aacuuuccua uuuauguaug gagcagcaag acugaaacug uugaggagcc cauggaggaa      900

gaagaagcag ccaaagaaga gaaagaagaa ucugaugaug aagcugcagu agaggaagaa      960

gaagaagaaa agaaaccaaa gacuaaaaaa guugaaaaaa cugucuggga cugggaacuu     1020

augaaugaua ucaaaccaau auggcagaga ccaucaaaag aaguagaaga agaugaauac     1080

aaagcuuucu acaaaucauu uucaaaggaa agugaugacc ccauggcuua uauucacuuu     1140

acugcugaag gggaaguuac cuucaaauca auuuuauuug uacccacauc ugcuccacgu     1200

ggucuguuug acgaauaugg aucuaaaaag agcgauuaca uuaagcucua ugugcgccgu     1260

guauucauca cagacgacuu ccaugauaug augccuaaau accucaauuu ugucaagggu     1320

gugguggacu cagaugaucu ccccuugaau guuucccgcg agacucuuca gcaacauaaa     1380

cugcuuaagg ugauuaggaa gaagcuuguu cguaaaacgc uggacaugau caagaagauu     1440

gcugaugaua aauacaauga uacuuuuugg aaagaauuug guaccaacau caagcuuggu     1500

gugauugaag accacucgaa ucgaacacgu cuugcuaaac uucuuagguu ccagucuucu     1560

caucauccaa cugacauuac uagccuagac caguaugugg aaagaaugaa ggaaaaacaa     1620

gacaaaaucu acuucauggc uggguccagc agaaaagagg cugaaucuuc uccauuuguu     1680

gagcgacuuc ugaaaaaggg cuaugaaguu auuuaccuca cagaaccugu ggaugaauac     1740

uguauucagg cccuucccga auuugauggg aagagguucc agaauguugc caaggaagga     1800

gugaaguucg augaaaguga gaaaacuaag gagagucgug aagcaguuga gaaagaauuu     1860

gagccucugc ugaauuggau gaaagauaaa gcccuuaagg acaagauuga aaaggcugug     1920

gugucucagc gccugacaga aucuccgugu gcuuuggugg ccagccagua cggauggucu     1980

ggcaacaugg agagaaucau gaaagcacaa gcguaccaaa cgggcaagga caucucuaca     2040

aauuacuaug cgagucagaa gaaaacauuu gaaauuaauc ccagacaccc gcugaucaga     2100

gacaugcuuc gacgaauuaa ggaagaugaa gaugauaaaa caguuuugga ucuugcugug     2160

guuuuguuug aaacagcaac gcuucgguca ggguaucuuu uaccagacac uaaagcauau     2220

ggagauagaa uagaaagaau gcuucgccuc aguuugaaca uugacccuga ugcaaaggug     2280

gaagaagagc ccgaagaaga accugaagag acagcagaag acacaacaga agacacagag     2340

caagacgaag augaagaaau ggauguggga acagaugaag aagaagaaac agcaaaggaa     2400

ucuacagcug aaaaagauga auuguaagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  1455
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (wt)

<400>  1455
gggagaaagc uuaccauggc gcgcgagcug cgggcgcugc ugcugugggg ccgccgccug       60

cggccuuugc ugcgggcgcc ggcgcuggcg gccgugccgg gaggaaaacc aauucugugu      120

ccucggagga ccacagccca guugggcccc aggcgaaacc cagccuggag cuugcaggca      180

ggacgacugu ucagcacgca gaccgccgag gacaaggagg aaccccugca cucgauuauc      240

agcagcacag agagcgugca ggguuccacu uccaaacaug aguuccaggc cgagacaaag      300

aagcuuuugg acauuguugc ccggucccug uacucagaaa aagagguguu uauacgggag      360

cugaucucca augccagcga ugccuuggaa aaacugcguc acaaacuggu gucugacggc      420

caagcacugc cagaaaugga gauucacuug cagaccaaug ccgagaaagg caccaucacc      480

auccaggaua cugguaucgg gaugacacag gaagagcugg uguccaaccu ggggacgauu      540

gccagaucgg ggucaaaggc cuuccuggau gcucugcaga accaggcuga ggccagcagc      600

aagaucaucg gccaguuugg aguggguuuc uacucagcuu ucaugguggc ugacagagug      660

gaggucuauu cccgcucggc agccccgggg agccuggguu accaguggcu uucagauggu      720

ucuggagugu uugaaaucgc cgaagcuucg ggaguuagaa ccgggacaaa aaucaucauc      780

caccugaaau ccgacugcaa ggaguuuucc agcgaggccc gggugcgaga ugugguaacg      840

aaguacagca acuucgucag cuuccccuug uacuugaaug gaaggcggau gaacaccuug      900

caggccaucu ggaugaugga ccccaaggau guccgugagu ggcaacauga ggaguucuac      960

cgcuacgucg cgcaggcuca cgacaagccc cgcuacaccc ugcacuauaa gacggacgca     1020

ccgcucaaca uccgcagcau cuucuacgug cccgacauga aaccguccau guuugaugug     1080

agccgggagc ugggcuccag cguugcacug uacagccgca aaguccucau ccagaccaag     1140

gccacggaca uccugcccaa guggcugcgc uucauccgag guguggugga cagugaggac     1200

auuccccuga accucagccg ggagcugcug caggagagcg cacucaucag gaaacuccgg     1260

gacguuuuac agcagaggcu gaucaaauuc uucauugacc agaguaaaaa agaugcugag     1320

aaguaugcaa aguuuuuuga agauuacggc cuguucaugc gggagggcau ugugaccgcc     1380

accgagcagg aggucaagga ggacauagca aagcugcugc gcuacgaguc cucggcgcug     1440

cccuccgggc agcuaaccag ccucucagaa uacgccagcc gcaugcgggc cggcacccgc     1500

aacaucuacu accugugcgc ccccaaccgu caccuggcag agcacucacc cuacuaugag     1560

gccaugaaga agaaagacac agagguucuc uucugcuuug agcaguuuga ugagcucacc     1620

cugcugcacc uucgugaguu ugacaagaag aagcugaucu cuguggagac ggacauaguc     1680

guggaucacu acaaggagga gaaguuugag gacagguccc cagccgccga gugccuauca     1740

gagaaggaga cggaggagcu cauggccugg augagaaaug ugcugggguc gcgugucacc     1800

aacgugaagg ugacccuccg acuggacacc cacccugcca uggucaccgu gcuggagaug     1860

ggggcugccc gccacuuccu gcgcaugcag cagcuggcca agacccagga ggagcgcgca     1920

cagcuccugc agcccacgcu ggagaucaac cccaggcacg cgcucaucaa gaagcugaau     1980

cagcugcgcg caagcgagcc uggccuggcu cagcugcugg uggaucagau auacgagaac     2040

gccaugauug cugcuggacu uguugacgac ccuagggcca uggugggccg cuugaaugag     2100

cugcuuguca aggcccugga gcgacacuga ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  1456
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (wt)

<400>  1456
gggagaaagc uuaccauggg aaaaaucagc agucuuccaa cccaauuauu uaagugcugc       60

uuuugugauu ucuugaaggu gaagaugcac accauguccu ccucgcaucu cuucuaccug      120

gcgcugugcc ugcucaccuu caccagcucu gccacggcug gaccggagac gcucugcggg      180

gcugagcugg uggaugcucu ucaguucgug uguggagaca ggggcuuuua uuucaacaag      240

cccacagggu auggcuccag cagucggagg gcgccucaga caggcaucgu ggaugagugc      300

ugcuuccgga gcugugaucu aaggaggcug gagauguauu gcgcaccccu caagccugcc      360

aagucagcuc gcucuguccg ugcccagcgc cacaccgaca ugcccaagac ccagaaggaa      420

guacauuuga agaacgcaag uagagggagu gcaggaaaca agaacuacag gauguaggga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  1457
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (wt)

<400>  1457
gggagaaagc uuaccauggg aaucccaaug gggaagucga ugcuggugcu ucucaccuuc       60

uuggccuucg ccucgugcug cauugcugcu uaccgcccca gugagacccu gugcggcggg      120

gagcuggugg acacccucca guucgucugu ggggaccgcg gcuucuacuu cagcaggccc      180

gcaagccgug ugagccgucg cagccguggc aucguugagg agugcuguuu ccgcagcugu      240

gaccuggccc uccuggagac guacugugcu acccccgcca aguccgagag ggacgugucg      300

accccuccga ccgugcuucc ggacaacuuc cccagauacc ccgugggcaa guucuuccaa      360

uaugacaccu ggaagcaguc cacccagcgc cugcgcaggg gccugccugc ccuccugcgu      420

gcccgccggg gucacgugcu cgccaaggag cucgaggcgu ucagggaggc caaacgucac      480

cguccccuga uugcucuacc cacccaagac cccgcccacg ggggcgcccc cccagagaug      540

gccagcaauc ggaagugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  1458
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (wt)

<400>  1458
gggagaaagc uuaccaugaa cuccuucucc acaagcgccu ucgguccagu ugccuucucc       60

cuggggcugc uccugguguu gccugcugcc uucccugccc caguaccccc aggagaagau      120

uccaaagaug uagccgcccc acacagacag ccacucaccu cuucagaacg aauugacaaa      180

caaauucggu acauccucga cggcaucuca gcccugagaa aggagacaug uaacaagagu      240

aacaugugug aaagcagcaa agaggcacug gcagaaaaca accugaaccu uccaaagaug      300

gcugaaaaag auggaugcuu ccaaucugga uucaaugagg agacuugccu ggugaaaauc      360

aucacugguc uuuuggaguu ugagguauac cuagaguacc uccagaacag auuugagagu      420

agugaggaac aagccagagc ugugcagaug aguacaaaag uccugaucca guuccugcag      480

aaaaaggcaa agaaucuaga ugcaauaacc accccugacc caaccacaaa ugccagccug      540

cugacgaagc ugcaggcaca gaaccagugg cugcaggaca ugacaacuca ucucauucug      600

cgcagcuuua aggaguuccu gcaguccagc cugagggcuc uucggcaaau guagggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  1459
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (wt)

<400>  1459
gggagaaagc uuaccaugcc cuugcuuugg cugagaggau uucuguuggc aaguugcugg       60

auuauaguga ggaguucccc caccccagga uccgaggggc acagcgcggc ccccgacugu      120

ccguccugug cgcuggccgc ccucccaaag gauguaccca acucucagcc agagauggug      180

gaggccguca agaagcacau uuuaaacaug cugcacuuga agaagagacc cgaugucacc      240

cagccgguac ccaaggcggc gcuucugaac gcgaucagaa agcuucaugu gggcaaaguc      300

ggggagaacg gguaugugga gauagaggau gacauuggaa ggagggcaga aaugaaugaa      360

cuuauggagc agaccucgga gaucaucacg uuugccgagu caggaacagc caggaagacg      420

cugcacuucg agauuuccaa ggaaggcagu gaccugucag ugguggagcg ugcagaaguc      480

uggcucuucc uaaaaguccc caaggccaac aggaccagga ccaaagucac cauccgccuc      540

uuccagcagc agaagcaccc gcagggcagc uuggacacag gggaagaggc cgaggaagug      600

ggcuuaaagg gggagaggag ugaacuguug cucucugaaa aaguaguaga cgcucggaag      660

agcaccuggc augucuuccc ugucuccagc agcauccagc gguugcugga ccagggcaag      720

agcucccugg acguucggau ugccugugag cagugccagg agaguggcgc cagcuugguu      780

cuccugggca agaagaagaa gaaagaagag gagggggaag ggaaaaagaa gggcggaggu      840

gaaggugggg caggagcaga ugaggaaaag gagcagucgc acagaccuuu ccucaugcug      900

caggcccggc agucugaaga ccacccucau cgccggcguc ggcggggcuu ggagugugau      960

ggcaagguca acaucugcug uaagaaacag uucuuuguca guuucaagga caucggcugg     1020

aaugacugga ucauugcucc cucuggcuau caugccaacu acugcgaggg ugagugcccg     1080

agccauauag caggcacguc cggguccuca cuguccuucc acucaacagu caucaaccac     1140

uaccgcaugc ggggccauag ccccuuugcc aaccucaaau cgugcugugu gcccaccaag     1200

cugagaccca uguccauguu guacuaugau gauggucaaa acaucaucaa aaaggacauu     1260

cagaacauga ucguggagga gugugggugc ucauagggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  1460
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (wt)

<400>  1460
gggagaaagc uuaccaugga cgggcugccc ggucgggcgc ugggggccgc cugccuucug       60

cugcuggcgg ccggcuggcu ggggccugag gccuggggcu cacccacgcc cccgccgacg      120

ccugccgcgc cgccgccacc cccgccaccc ggauccccgg guggcucgca ggacaccugu      180

acgucgugcg gcggcuuccg gcggccagag gagcucggcc gaguggacgg cgacuuccug      240

gaggcgguga agcggcacau cuugagccgc cugcagaugc ggggccggcc caacaucacg      300

cacgccgugc cuaaggccgc cauggucacg gcccugcgca agcugcacgc gggcaaggug      360

cgcgaggacg gccgcgugga gaucccgcac cucgacggcc acgccagccc gggcgccgac      420

ggccaggagc gcguuuccga aaucaucagc uucgccgaga cagauggccu cgccuccucc      480

cggguccgcc uauacuucuu caucuccaac gaaggcaacc agaaccuguu ugugguccag      540

gccagccugu ggcuuuaccu gaaacuccug cccuacgucc uggagaaggg cagccggcgg      600

aaggugcggg ucaaagugua cuuccaggag cagggccacg gugacaggug gaacauggug      660

gagaagaggg uggaccucaa gcgcagcggc uggcauaccu ucccacucac ggaggccauc      720

caggccuugu uugagcgggg cgagcggcga cucaaccuag acgugcagug ugacagcugc      780

caggagcugg ccguggugcc gguguucgug gacccaggcg aagagucgca ccggcccuuu      840

gugguggugc aggcucggcu gggcgacagc aggcaccgca uucgcaagcg aggccuggag      900

ugcgauggcc ggaccaaccu cuguugcagg caacaguucu ucauugacuu ccgccucauc      960

ggcuggaacg acuggaucau agcacccacc ggcuacuacg ggaacuacug ugagggcagc     1020

ugcccagccu accuggcagg gguccccggc ucugccuccu ccuuccacac ggcuguggug     1080

aaccaguacc gcaugcgggg ucugaacccc ggcacgguga acuccugcug cauucccacc     1140

aagcugagca ccauguccau gcuguacuuc gaugaugagu acaacaucgu caagcgggac     1200

gugcccaaca ugauugugga ggagugcggc ugcgccugag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  1461
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (wt)

<400>  1461
gggagaaagc uuaccauggc ucucagaguc cuucuguuaa cagccuugac cuuaugucau       60

ggguucaacu uggacacuga aaacgcaaug accuuccaag agaacgcaag gggcuucggg      120

cagagcgugg uccagcuuca gggauccagg guggugguug gagcccccca ggagauagug      180

gcugccaacc aaaggggcag ccucuaccag ugcgacuaca gcacaggcuc augcgagccc      240

auccgccugc agguccccgu ggaggccgug aacauguccc ugggccuguc ccuggcagcc      300

accaccagcc ccccucagcu gcuggccugu ggucccaccg ugcaccagac uugcagugag      360

aacacguaug ugaaagggcu cugcuuccug uuuggaucca accuacggca gcagccccag      420

aaguucccag aggcccuccg aggguguccu caagaggaua gugacauugc cuucuugauu      480

gauggcucug guagcaucau cccacaugac uuucggcgga ugaaggaguu ugucucaacu      540

gugauggagc aauuaaaaaa guccaaaacc uuguucucuu ugaugcagua cucugaagaa      600

uuccggauuc acuuuaccuu caaagaguuc cagaacaacc cuaacccaag aucacuggug      660

aagccaauaa cgcagcugcu ugggcggaca cacacggcca cgggcauccg caaaguggua      720

cgagagcugu uuaacaucac caacggagcc cgaaagaaug ccuuuaagau ccuaguuguc      780

aucacggaug gagaaaaguu uggcgauccc uugggauaug aggaugucau cccugaggca      840

gacagagagg gagucauucg cuacgucauu ggggugggag augccuuccg cagugagaaa      900

ucccgccaag agcuuaauac caucgcaucc aagccgccuc gugaucacgu guuccaggug      960

aauaacuuug aggcucugaa gaccauucag aaccagcuuc gggagaagau cuuugcgauc     1020

gaggguacuc agacaggaag uagcagcucc uuugagcaug agaugucuca ggaaggcuuc     1080

agcgcugcca ucaccucuaa uggccccuug cugagcacug uggggagcua ugacugggcu     1140

gguggagucu uucuauauac aucaaaggag aaaagcaccu ucaucaacau gaccagagug     1200

gauucagaca ugaaugaugc uuacuugggu uaugcugccg ccaucaucuu acggaaccgg     1260

gugcaaagcc ugguucuggg ggcaccucga uaucagcaca ucggccuggu agcgauguuc     1320

aggcagaaca cuggcaugug ggaguccaac gcuaauguca agggcaccca gaucggcgcc     1380

uacuucgggg ccucccucug cuccguggac guggacagca acggcagcac cgaccugguc     1440

cucaucgggg ccccccauua cuacgagcag acccgagggg gccagguguc cgugugcccc     1500

uugcccaggg ggagggcucg guggcagugu gaugcuguuc ucuacgggga gcagggccaa     1560

cccuggggcc gcuuuggggc agcccuaaca gugcuggggg acguaaaugg ggacaagcug     1620

acggacgugg ccauuggggc cccaggagag gaggacaacc ggggugcugu uuaccuguuu     1680

cacggaaccu caggaucugg caucagcccc ucccauagcc agcggauagc aggcuccaag     1740

cucucuccca ggcuccagua uuuuggucag ucacugagug ggggccagga ccucacaaug     1800

gauggacugg uagaccugac uguaggagcc caggggcacg ugcugcugcu caggucccag     1860

ccaguacuga gagucaaggc aaucauggag uucaauccca gggaaguggc aaggaaugua     1920

uuugagugua augaucaggu ggugaaaggc aaggaagccg gagaggucag agucugccuc     1980

cauguccaga agagcacacg ggaucggcua agagaaggac agauccagag uguugugacu     2040

uaugaccugg cucuggacuc cggccgccca cauucccgcg ccgucuucaa ugagacaaag     2100

aacagcacac gcagacagac acaggucuug gggcugaccc agacuuguga gacccugaaa     2160

cuacaguugc cgaauugcau cgaggaccca gugagcccca uugugcugcg ccugaacuuc     2220

ucucuggugg gaacgccauu gucugcuuuc gggaaccucc ggccagugcu ggcggaggau     2280

gcucagagac ucuucacagc cuuguuuccc uuugagaaga auuguggcaa ugacaacauc     2340

ugccaggaug accucagcau caccuucagu uucaugagcc uggacugccu cguggugggu     2400

gggccccggg aguucaacgu gacagugacu gugagaaaug auggugagga cuccuacagg     2460

acacagguca ccuucuucuu cccgcuugac cuguccuacc ggaagguguc cacgcuccag     2520

aaccagcgcu cacagcgauc cuggcgccug gccugugagu cugccuccuc caccgaagug     2580

ucuggggccu ugaagagcac cagcugcagc auaaaccacc ccaucuuccc ggaaaacuca     2640

gaggucaccu uuaauaucac guuugaugua gacucuaagg cuucccuugg aaacaaacug     2700

cuccucaagg ccaaugugac cagugagaac aacaugccca gaaccaacaa aaccgaauuc     2760

caacuggagc ugccggugaa auaugcuguc uacauggugg ucaccagcca uggggucucc     2820

acuaaauauc ucaacuucac ggccucagag aauaccaguc gggucaugca gcaucaauau     2880

caggucagca accuggggca gaggagccuc cccaucagcc ugguguucuu ggugcccguc     2940

cggcugaacc agacugucau augggaccgc ccccagguca ccuucuccga gaaccucucg     3000

aguacgugcc acaccaagga gcgcuugccc ucucacuccg acuuucuggc ugagcuucgg     3060

aaggcccccg uggugaacug cuccaucgcu gucugccaga gaauccagug ugacaucccg     3120

uucuuuggca uccaggaaga auucaaugcu acccucaaag gcaaccucuc guuugacugg     3180

uacaucaaga ccucgcauaa ccaccuccug aucgugagca cagcugagau cuuguuuaac     3240

gauuccgugu ucacccugcu gccgggacag ggggcguuug ugagguccca gacggagacc     3300

aaaguggagc cguucgaggu ccccaacccc cugccgcuca ucgugggcag cucugucggg     3360

ggacugcugc uccuggcccu caucaccgcc gcgcuguaca agcucggcuu cuucaagcgg     3420

caauacaagg acaugaugag ugaagggggu cccccggggg ccgaacccca guagggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  1462
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (wt)

<400>  1462
gggagaaagc uuaccauguu cucccugaag acgcuuccau uucugcucuu acuccaugug       60

cagauuucca aggccuuucc uguaucuucu aaagagaaaa auacaaaaac uguucaggac      120

uaccuggaaa aguucuacca auuaccaagc aaccaguauc agucuacaag gaagaauggc      180

acuaauguga ucguugaaaa gcuuaaagaa augcagcgau uuuuuggguu gaaugugacg      240

gggaagccaa augaggaaac ucuggacaug augaaaaagc cucgcugugg agugccugac      300

aguggugguu uuauguuaac cccaggaaac cccaaguggg aacgcacuaa cuugaccuac      360

aggauucgaa acuauacccc acagcuguca gaggcugagg uagaaagagc uaucaaggau      420

gccuuugaac ucuggagugu ugcaucaccu cucaucuuca ccaggaucuc acagggagag      480

gcagauauca acauugcuuu uuaccaaaga gaucacggug acaauucucc auuugaugga      540

cccaauggaa uccuugcuca ugccuuucag ccaggccaag guauuggagg agaugcucau      600

uuugaugccg aagaaacaug gaccaacacc uccgcaaauu acaacuuguu ucuuguugcu      660

gcucaugaau uuggccauuc uuuggggcuc gcucacuccu cugacccugg ugccuugaug      720

uaucccaacu augcuuucag ggaaaccagc aacuacucac ucccucaaga ugacaucgau      780

ggcauucagg ccaucuaugg acuuucaagc aacccuaucc aaccuacugg accaagcaca      840

cccaaacccu gugaccccag uuugacauuu gaugcuauca ccacacuccg uggagaaaua      900

cuuuucuuua aagacaggua cuucuggaga aggcauccuc agcuacaaag agucgaaaug      960

aauuuuauuu cucuauucug gccaucccuu ccaacuggua uacaggcugc uuaugaagau     1020

uuugacagag accucauuuu ccuauuuaaa ggcaaccaau acugggcucu gaguggcuau     1080

gauauucugc aagguuaucc caaggauaua ucaaacuaug gcuuccccag cagcguccaa     1140

gcaauugacg cagcuguuuu cuacagaagu aaaacauacu ucuuuguaaa ugaccaauuc     1200

uggagauaug auaaccaaag acaauucaug gagccagguu aucccaaaag cauaucaggu     1260

gccuuuccag gaauagagag uaaaguugau gcaguuuucc agcaagaaca uuucuuccau     1320

gucuucagug gaccaagaua uuacgcauuu gaucuuauug cucagagagu uaccagaguu     1380

gcaagaggca auaaauggcu uaacuguaga uauggcugag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  1463
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (wt)

<400>  1463
gggagaaagc uuaccaugag ccucuggcag ccccuggucc uggugcuccu ggugcugggc       60

ugcugcuuug cugcccccag acagcgccag uccacccuug ugcucuuccc uggagaccug      120

agaaccaauc ucaccgacag gcagcuggca gaggaauacc uguaccgcua ugguuacacu      180

cggguggcag agaugcgugg agagucgaaa ucucuggggc cugcgcugcu gcuucuccag      240

aagcaacugu cccugcccga gaccggugag cuggauagcg ccacgcugaa ggccaugcga      300

accccacggu gcgggguccc agaccugggc agauuccaaa ccuuugaggg cgaccucaag      360

uggcaccacc acaacaucac cuauuggauc caaaacuacu cggaagacuu gccgcgggcg      420

gugauugacg acgccuuugc ccgcgccuuc gcacugugga gcgcggugac gccgcucacc      480

uucacucgcg uguacagccg ggacgcagac aucgucaucc aguuuggugu cgcggagcac      540

ggagacgggu aucccuucga cgggaaggac gggcuccugg cacacgccuu uccuccuggc      600

cccggcauuc agggagacgc ccauuucgac gaugacgagu uguggucccu gggcaagggc      660

gucgugguuc caacucgguu uggaaacgca gauggcgcgg ccugccacuu ccccuucauc      720

uucgagggcc gcuccuacuc ugccugcacc accgacgguc gcuccgacgg cuugcccugg      780

ugcaguacca cggccaacua cgacaccgac gaccgguuug gcuucugccc cagcgagaga      840

cucuacaccc aggacggcaa ugcugauggg aaacccugcc aguuuccauu caucuuccaa      900

ggccaauccu acuccgccug caccacggac ggucgcuccg acggcuaccg cuggugcgcc      960

accaccgcca acuacgaccg ggacaagcuc uucggcuucu gcccgacccg agcugacucg     1020

acggugaugg ggggcaacuc ggcgggggag cugugcgucu uccccuucac uuuccugggu     1080

aaggaguacu cgaccuguac cagcgagggc cgcggagaug ggcgccucug gugcgcuacc     1140

accucgaacu uugacagcga caagaagugg ggcuucugcc cggaccaagg auacaguuug     1200

uuccucgugg cggcgcauga guucggccac gcgcugggcu uagaucauuc cucagugccg     1260

gaggcgcuca uguacccuau guaccgcuuc acugaggggc cccccuugca uaaggacgac     1320

gugaauggca uccggcaccu cuaugguccu cgcccugaac cugagccacg gccuccaacc     1380

accaccacac cgcagcccac ggcucccccg acggucugcc ccaccggacc ccccacuguc     1440

caccccucag agcgccccac agcuggcccc acaggucccc ccucagcugg ccccacaggu     1500

ccccccacug cuggcccuuc uacggccacu acugugccuu ugaguccggu ggacgaugcc     1560

ugcaacguga acaucuucga cgccaucgcg gagauuggga accagcugua uuuguucaag     1620

gaugggaagu acuggcgauu cucugagggc agggggagcc ggccgcaggg ccccuuccuu     1680

aucgccgaca aguggcccgc gcugccccgc aagcuggacu cggucuuuga ggagcggcuc     1740

uccaagaagc uuuucuucuu cucugggcgc cagguguggg uguacacagg cgcgucggug     1800

cugggcccga ggcgucugga caagcugggc cugggagccg acguggccca ggugaccggg     1860

gcccuccgga guggcagggg gaagaugcug cuguucagcg ggcggcgccu cuggagguuc     1920

gacgugaagg cgcagauggu ggauccccgg agcgccagcg agguggaccg gauguucccc     1980

ggggugccuu uggacacgca cgacgucuuc caguaccgag agaaagccua uuucugccag     2040

gaccgcuucu acuggcgcgu gaguucccgg agugaguuga accaggugga ccaagugggc     2100

uacgugaccu augacauccu gcagugcccu gaggacuagg gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  1464
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (wt)

<400>  1464
gggagaaagc uuaccaugca uccagggguc cuggcugccu uccucuucuu gagcuggacu       60

cauugucggg cccugccccu ucccaguggu ggugaugaag augauuuguc ugaggaagac      120

cuccaguuug cagagcgcua ccugagauca uacuaccauc cuacaaaucu cgcgggaauc      180

cugaaggaga augcagcaag cuccaugacu gagaggcucc gagaaaugca gucuuucuuc      240

ggcuuagagg ugacuggcaa acuugacgau aacaccuuag augucaugaa aaagccaaga      300

ugcgggguuc cugauguggg ugaauacaau guuuucccuc gaacucuuaa augguccaaa      360

augaauuuaa ccuacagaau ugugaauuac accccugaua ugacucauuc ugaagucgaa      420

aaggcauuca aaaaagccuu caaaguuugg uccgauguaa cuccucugaa uuuuaccaga      480

cuucacgaug gcauugcuga caucaugauc ucuuuuggaa uuaaggagca uggcgacuuc      540

uacccauuug augggcccuc uggccugcug gcucaugcuu uuccuccugg gccaaauuau      600

ggaggagaug cccauuuuga ugaugaugaa accuggacaa guaguuccaa aggcuacaac      660

uuguuucuug uugcugcgca ugaguucggc cacuccuuag gucuugacca cuccaaggac      720

ccuggagcac ucauguuucc uaucuacacc uacaccggca aaagccacuu uaugcuuccu      780

gaugacgaug uacaagggau ccagucucuc uaugguccag gagaugaaga ccccaacccu      840

aaacauccaa aaacgccaga caaaugugac ccuuccuuau cccuugaugc cauuaccagu      900

cuccgaggag aaacaaugau cuuuaaagac agauucuucu ggcgccugca uccucagcag      960

guugaugcgg agcuguuuuu aacgaaauca uuuuggccag aacuucccaa ccguauugau     1020

gcugcauaug agcacccuuc ucaugaccuc aucuucaucu ucagagguag aaaauuuugg     1080

gcucuuaaug guuaugacau ucuggaaggu uaucccaaaa aaauaucuga acugggucuu     1140

ccaaaagaag uuaagaagau aagugcagcu guucacuuug aggauacagg caagacucuc     1200

cuguucucag gaaaccaggu cuggagauau gaugauacua accauauuau ggauaaagac     1260

uauccgagac uaauagaaga agacuuccca ggaauuggug auaaaguaga ugcugucuau     1320

gagaaaaaug guuauaucua uuuuuucaac ggacccauac aguuugaaua cagcaucugg     1380

aguaaccgua uuguucgcgu caugccagca aauuccauuu ugugguguua aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  1465
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (wt)

<400>  1465
gggagaaagc uuaccaugga aacuccaaac accacagagg acuaugacac gaccacagag       60

uuugacuaug gggaugcaac uccgugccag aaggugaacg agagggccuu uggggcccaa      120

cugcugcccc cucuguacuc cuugguauuu gucauuggcc ugguuggaaa cauccuggug      180

guccuggucc uugugcaaua caagaggcua aaaaacauga ccagcaucua ccuccugaac      240

cuggccauuu cugaccugcu cuuccuguuc acgcuucccu ucuggaucga cuacaaguug      300

aaggaugacu ggguuuuugg ugaugccaug uguaagaucc ucucuggguu uuauuacaca      360

ggcuuguaca gcgagaucuu uuucaucauc cugcugacga uugacaggua ccuggccauc      420

guccacgccg uguuugccuu gcgggcacgg accgucacuu uuggugucau caccagcauc      480

aucauuuggg cccuggccau cuuggcuucc augccaggcu uauacuuuuc caagacccaa      540

ugggaauuca cucaccacac cugcagccuu cacuuuccuc acgaaagccu acgagagugg      600

aagcuguuuc aggcucugaa acugaaccuc uuugggcugg uauugccuuu guuggucaug      660

aucaucugcu acacagggau uauaaagauu cugcuaagac gaccaaauga gaagaaaucc      720

aaagcugucc guuugauuuu ugucaucaug aucaucuuuu uucucuuuug gacccccuac      780

aauuugacua uacuuauuuc uguuuuccaa gacuuccugu ucacccauga gugugagcag      840

agcagacauu uggaccuggc ugugcaagug acggagguga ucgccuacac gcacugcugu      900

gucaacccag ugaucuacgc cuucguuggu gagagguucc ggaaguaccu gcggcaguug      960

uuccacaggc guguggcugu gcaccugguu aaauggcucc ccuuccucuc cguggacagg     1020

cuggagaggg ucagcuccac aucucccucc acaggggagc augaacucuc ugcuggguuc     1080

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  1466
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (wt)

<400>  1466
gggagaaagc uuaccaugag gaccuuggcu ugccugcugc uccucggcug cggauaccuc       60

gcccauguuc uggccgagga agccgagauc ccccgcgagg ugaucgagag gcuggcccgc      120

agucagaucc acagcauccg ggaccuccag cgacuccugg agauagacuc cguagggagu      180

gaggauucuu uggacaccag ccugagagcu cacggggucc augccacuaa gcaugugccc      240

gagaagcggc cccugcccau ucggaggaag agaagcaucg aggaagcugu ccccgcuguc      300

ugcaagacca ggacggucau uuacgagauu ccucggaguc aggucgaccc cacguccgcc      360

aacuuccuga ucuggccccc gugcguggag gugaaacgcu gcaccggcug cugcaacacg      420

agcaguguca agugccagcc cucccgcguc caccaccgca gcgucaaggu ggccaaggug      480

gaauacguca ggaagaagcc aaaauuaaaa gaaguccagg ugagguuaga ggagcauuug      540

gagugcgccu gcgcgaccac aagccugaau ccggauuauc gggaagagga cacgggaagg      600

ccuagggagu cagguaaaaa acggaaaaga aaaagguuaa aacccaccua aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  1467
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (wt)

<400>  1467
gggagaaagc uuaccaugaa ucgcugcugg gcgcucuucc ugucucucug cugcuaccug       60

cgucugguca gcgccgaggg ggaccccauu cccgaggagc uuuaugagau gcugagugac      120

cacucgaucc gcuccuuuga ugaucuccaa cgccugcugc acggagaccc cggagaggaa      180

gauggggccg aguuggaccu gaacaugacc cgcucccacu cuggaggcga gcuggagagc      240

uuggcucgug gaagaaggag ccuggguucc cugaccauug cugagccggc caugaucgcc      300

gagugcaaga cgcgcaccga gguguucgag aucucccggc gccucauaga ccgcaccaac      360

gccaacuucc ugguguggcc gcccugugug gaggugcagc gcugcuccgg cugcugcaac      420

aaccgcaacg ugcagugccg ccccacccag gugcagcugc gaccugucca ggugagaaag      480

aucgagauug ugcggaagaa gccaaucuuu aagaaggcca cggugacgcu ggaagaccac      540

cuggcaugca agugugagac aguggcagcu gcacggccug ugacccgaag cccggggggu      600

ucccaggagc agcgagccaa aacgccccaa acucggguga ccauucggac ggugcgaguc      660

cgccggcccc ccaagggcaa gcaccggaaa uucaagcaca cgcaugacaa gacggcacug      720

aaggagaccc uuggagccua gggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  1468
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (wt)

<400>  1468
gggagaaagc uuaccaugag ccucuucggg cuucuccugc ugacaucugc ccuggccggc       60

cagagacagg ggacucaggc ggaauccaac cugaguagua aauuccaguu uuccagcaac      120

aaggaacaga acggaguaca agauccucag caugagagaa uuauuacugu gucuacuaau      180

ggaaguauuc acagcccaag guuuccucau acuuauccaa gaaauacggu cuugguaugg      240

agauuaguag caguagagga aaauguaugg auacaacuua cguuugauga aagauuuggg      300

cuugaagacc cagaagauga cauaugcaag uaugauuuug uagaaguuga ggaacccagu      360

gauggaacua uauuagggcg cugguguggu ucugguacug uaccaggaaa acagauuucu      420

aaaggaaauc aaauuaggau aagauuugua ucugaugaau auuuuccuuc ugaaccaggg      480

uucugcaucc acuacaacau ugucaugcca caauucacag aagcugugag uccuucagug      540

cuacccccuu cagcuuugcc acuggaccug cuuaauaaug cuauaacugc cuuuaguacc      600

uuggaagacc uuauucgaua ucuugaacca gagagauggc aguuggacuu agaagaucua      660

uauaggccaa cuuggcaacu ucuuggcaag gcuuuuguuu uuggaagaaa auccagagug      720

guggaucuga accuucuaac agaggaggua agauuauaca gcugcacacc ucguaacuuc      780

ucagugucca uaagggaaga acuaaagaga accgauacca uuuucuggcc agguugucuc      840

cugguuaaac gcuguggugg gaacugugcc uguugucucc acaauugcaa ugaaugucaa      900

ugugucccaa gcaaaguuac uaaaaaauac cacgaggucc uucaguugag accaaagacc      960

ggugucaggg gauugcacaa aucacucacc gacguggccc uggagcacca ugaggagugu     1020

gacugugugu gcagagggag cacaggagga uagggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  1469
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (wt)

<400>  1469
gggagaaagc uuaccaugca ccggcucauc uuugucuaca cucuaaucug cgcaaacuuu       60

ugcagcuguc gggacacuuc ugcaaccccg cagagcgcau ccaucaaagc uuugcgcaac      120

gccaaccuca ggcgagauga cuuguaccga agagaugaga ccauccaggu gaaaggaaac      180

ggcuacgugc agaguccuag auucccgaac agcuacccca ggaaccugcu ccugacaugg      240

cggcuucacu cucaggagaa uacacggaua cagcuagugu uugacaauca guuuggauua      300

gaggaagcag aaaaugauau cuguagguau gauuuugugg aaguugaaga uauauccgaa      360

accaguacca uuauuagagg acgauggugu ggacacaagg aaguuccucc aaggauaaaa      420

ucaagaacga accaaauuaa aaucacauuc aaguccgaug acuacuuugu ggcuaaaccu      480

ggauucaaga uuuauuauuc uuugcuggaa gauuuccaac ccgcagcagc uucagagacc      540

aacugggaau cugucacaag cucuauuuca gggguauccu auaacucucc aucaguaacg      600

gaucccacuc ugauugcgga ugcucuggac aaaaaaauug cagaauuuga uacaguggaa      660

gaucugcuca aguacuucaa uccagaguca uggcaagaag aucuugagaa uauguaucug      720

gacaccccuc gguaucgagg caggucauac caugaccgga agucaaaagu ugaccuggau      780

aggcucaaug augaugccaa gcguuacagu ugcacuccca ggaauuacuc ggucaauaua      840

agagaagagc ugaaguuggc caaugugguc uucuuuccac guugccuccu cgugcagcgc      900

uguggaggaa auuguggcug uggaacuguc aacuggaggu ccugcacaug caauucaggg      960

aaaaccguga aaaaguauca ugagguauua caguuugagc cuggccacau caagaggagg     1020

gguagagcua agaccauggc ucuaguugac auccaguugg aucaccauga acgaugugau     1080

uguaucugca gcucaagacc accucgauaa ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  1470
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (wt)

<400>  1470
gggagaaagc uuaccauggu cacccacagc aaguuucccg ccgccgggau gagccgcccc       60

cuggacacca gccugcgccu caagaccuuc agcuccaaga gcgaguacca gcugguggug      120

aacgcagugc gcaagcugca ggagagcggc uucuacugga gcgcagugac cggcggcgag      180

gcgaaccugc ugcucagugc cgagcccgcc ggcaccuuuc ugauccgcga cagcucggac      240

cagcgccacu ucuucacgcu cagcgucaag acccagucug ggaccaagaa ccugcgcauc      300

cagugugagg ggggcagcuu cucucugcag agcgaucccc ggagcacgca gcccgugccc      360

cgcuucgacu gcgugcucaa gcuggugcac cacuacaugc cgcccccugg agcccccucc      420

uuccccucgc caccuacuga acccuccucc gaggugcccg agcagccguc ugcccagcca      480

cucccuggga guccccccag aagagccuau uacaucuacu ccgggggcga gaagaucccc      540

cugguguuga gccggccccu cuccuccaac guggccacuc uucagcaucu cugucggaag      600

accgucaacg gccaccugga cuccuaugag aaagucaccc agcugccggg gcccauucgg      660

gaguuccugg accaguacga ugccccgcuu uaaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  1471
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (wt)

<400>  1471
gggagaaagc uuaccauggu ccccucggcu ggacagcucg cccuguucgc ucuggguauu       60

guguuggcug cgugccaggc cuuggagaac agcacguccc cgcugagugc agacccgccc      120

guggcugcag cagugguguc ccauuuuaau gacugcccag auucccacac ucaguucugc      180

uuccauggaa ccugcagguu uuuggugcag gaggacaagc cagcaugugu cugccauucu      240

ggguacguug gugcacgcug ugagcaugcg gaccuccugg ccgugguggc ugccagccag      300

aagaagcagg ccaucaccgc cuugguggug gucuccaucg uggcccuggc uguccuuauc      360

aucacaugug ugcugauaca cugcugccag guccgaaaac acugugagug gugccgggcc      420

cucaucugcc ggcacgagaa gcccagcgcc cuccugaagg gaagaaccgc uugcugccac      480

ucagaaacag uggucugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  1472
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (wt)

<400>  1472
gggagaaagc uuaccaugcc gcccuccggg cugcggcugc ugccgcugcu gcuaccgcug       60

cuguggcuac uggugcugac gccuggccgg ccggccgcgg gacuauccac cugcaagacu      120

aucgacaugg agcuggugaa gcggaagcgc aucgaggcca uccgcggcca gauccugucc      180

aagcugcggc ucgccagccc cccgagccag ggggaggugc cgcccggccc gcugcccgag      240

gccgugcucg cccuguacaa cagcacccgc gaccgggugg ccggggagag ugcagaaccg      300

gagcccgagc cugaggccga cuacuacgcc aaggagguca cccgcgugcu aaugguggaa      360

acccacaacg aaaucuauga caaguucaag cagaguacac acagcauaua uauguucuuc      420

aacacaucag agcuccgaga agcgguaccu gaacccgugu ugcucucccg ggcagagcug      480

cgucugcuga ggcucaaguu aaaaguggag cagcacgugg agcuguacca gaaauacagc      540

aacaauuccu ggcgauaccu cagcaaccgg cugcuggcac ccagcgacuc gccagagugg      600

uuaucuuuug augucaccgg aguugugcgg cagugguuga gccguggagg ggaaauugag      660

ggcuuucgcc uuagcgccca cugcuccugu gacagcaggg auaacacacu gcaaguggac      720

aucaacgggu ucacuaccgg ccgccgaggu gaccuggcca ccauucaugg caugaaccgg      780

ccuuuccugc uucucauggc caccccgcug gagagggccc agcaucugca aagcucccgg      840

caccgccgag cccuggacac caacuauugc uucagcucca cggagaagaa cugcugcgug      900

cggcagcugu acauugacuu ccgcaaggac cucggcugga aguggaucca cgagcccaag      960

ggcuaccaug ccaacuucug ccucgggccc ugccccuaca uuuggagccu ggacacgcag     1020

uacagcaagg uccuggcccu guacaaccag cauaacccgg gcgccucggc ggcgccgugc     1080

ugcgugccgc aggcgcugga gccgcugccc aucguguacu acgugggccg caagcccaag     1140

guggagcagc uguccaacau gaucgugcgc uccugcaagu gcagcugagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  1473
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (wt)

<400>  1473
gggagaaagc uuaccaugca cuacugugug cugagcgcuu uucugauccu gcaucugguc       60

acggucgcgc ucagccuguc uaccugcagc acacucgaua uggaccaguu caugcgcaag      120

aggaucgagg cgauccgcgg gcagauccug agcaagcuga agcucaccag ucccccagaa      180

gacuauccug agcccgagga aguccccccg gaggugauuu ccaucuacaa cagcaccagg      240

gacuugcucc aggagaaggc gagccggagg gcggccgccu gcgagcgcga gaggagcgac      300

gaagaguacu acgccaagga gguuuacaaa auagacaugc cgcccuucuu ccccuccgaa      360

aaugccaucc cgcccacuuu cuacagaccc uacuucagaa uuguucgauu ugacgucuca      420

gcaauggaga agaaugcuuc caauuuggug aaagcagagu ucagagucuu ucguuugcag      480

aacccaaaag ccagagugcc ugaacaacgg auugagcuau aucagauucu caaguccaaa      540

gauuuaacau cuccaaccca gcgcuacauc gacagcaaag uugugaaaac aagagcagaa      600

ggcgaauggc ucuccuucga uguaacugau gcuguucaug aauggcuuca ccauaaagac      660

aggaaccugg gauuuaaaau aagcuuacac ugucccugcu gcacuuuugu accaucuaau      720

aauuacauca ucccaaauaa aagugaagaa cuagaagcaa gauuugcagg uauugauggc      780

accuccacau auaccagugg ugaucagaaa acuauaaagu ccacuaggaa aaaaaacagu      840

gggaagaccc cacaucuccu gcuaauguua uugcccuccu acagacuuga gucacaacag      900

accaaccggc ggaagaagcg ugcuuuggau gcggccuauu gcuuuagaaa ugugcaggau      960

aauugcugcc uacguccacu uuacauugau uucaagaggg aucuagggug gaaauggaua     1020

cacgaaccca aaggguacaa ugccaacuuc ugugcuggag caugcccgua uuuauggagu     1080

ucagacacuc agcacagcag gguccugagc uuauauaaua ccauaaaucc agaagcaucu     1140

gcuucuccuu gcugcguguc ccaagauuua gaaccucuaa ccauucucua cuacauuggc     1200

aaaacaccca agauugaaca gcuuucuaau augauuguaa agucuugcaa augcagcuaa     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  1474
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (wt)

<400>  1474
gggagaaagc uuaccaugaa gaugcacuug caaagggcuc uggugguccu ggcccugcug       60

aacuuugcca cggucagccu cucucugucc acuugcacca ccuuggacuu cggccacauc      120

aagaagaaga ggguggaagc cauuagggga cagaucuuga gcaagcucag gcucaccagc      180

cccccugagc caacggugau gacccacguc cccuaucagg uccuggcccu uuacaacagc      240

acccgggagc ugcuggagga gaugcauggg gagagggagg aaggcugcac ccaggaaaac      300

accgagucgg aauacuaugc caaagaaauc cauaaauucg acaugaucca ggggcuggcg      360

gagcacaacg aacuggcugu cugcccuaaa ggaauuaccu ccaagguuuu ccgcuucaau      420

guguccucag uggagaaaaa uagaaccaac cuauuccgag cagaauuccg ggucuugcgg      480

gugcccaacc ccagcucuaa gcggaaugag cagaggaucg agcucuucca gauccuucgg      540

ccagaugagc acauugccaa acagcgcuau aucgguggca agaaucugcc cacacggggc      600

acugccgagu ggcuguccuu ugaugucacu gacacugugc gugaguggcu guugagaaga      660

gaguccaacu uaggucuaga aaucagcauu cacuguccau gucacaccuu ucagcccaau      720

ggagauaucc uggaaaacau ucacgaggug auggaaauca aauucaaagg cguggacaau      780

gaggaugacc auggccgugg agaucugggg cgccucaaga agcagaagga ucaccacaac      840

ccucaucuaa uccucaugau gauuccccca caccggcucg acaacccggg ccaggggggu      900

cagaggaaga agcgggcuuu ggacaccaau uacugcuucc gcaacuugga ggagaacugc      960

ugugugcgcc cccucuacau ugacuuccga caggaucugg gcuggaagug gguccaugaa     1020

ccuaagggcu acuaugccaa cuucugcuca ggcccuugcc cauaccuccg cagugcagac     1080

acaacccaca gcacggugcu gggacuguac aacacucuga acccugaagc aucugccucg     1140

ccuugcugcg ugccccagga ccuggagccc cugaccaucc uguacuaugu ugggaggacc     1200

cccaaagugg agcagcucuc caacauggug gugaagucuu guaaauguag cugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  1475
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (wt)

<400>  1475
gggagaaagc uuaccauggc gcccgucgcc gucugggccg cgcuggccgu cggacuggag       60

cucugggcug cggcgcacgc cuugcccgcc cagguggcau uuacacccua cgccccggag      120

cccgggagca caugccggcu cagagaauac uaugaccaga cagcucagau gugcugcagc      180

aaaugcucgc cgggccaaca ugcaaaaguc uucuguacca agaccucgga caccgugugu      240

gacuccugug aggacagcac auacacccag cucuggaacu ggguucccga gugcuugagc      300

uguggcuccc gcuguagcuc ugaccaggug gaaacucaag ccugcacucg ggaacagaac      360

cgcaucugca ccugcaggcc cggcugguac ugcgcgcuga gcaagcagga ggggugccgg      420

cugugcgcgc cgcugcgcaa gugccgcccg ggcuucggcg uggccagacc aggaacugaa      480

acaucagacg uggugugcaa gcccugugcc ccggggacgu ucuccaacac gacuucaucc      540

acggauauuu gcaggcccca ccagaucugu aacguggugg ccaucccugg gaaugcaagc      600

auggaugcag ucugcacguc cacguccccc acccggagua uggccccagg ggcaguacac      660

uuaccccagc caguguccac acgaucccaa cacacgcagc caacuccaga acccagcacu      720

gcuccaagca ccuccuuccu gcucccaaug ggccccagcc ccccagcuga agggagcacu      780

ggcgacuucg cucuuccagu uggacugauu guggguguga cagccuuggg ucuacuaaua      840

auaggagugg ugaacugugu caucaugacc caggugaaaa agaagcccuu gugccugcag      900

agagaagcca aggugccuca cuugccugcc gauaaggccc gggguacaca gggccccgag      960

cagcagcacc ugcugaucac agcgccgagc uccagcagca gcucccugga gagcucggcc     1020

agugcguugg acagaagggc gcccacucgg aaccagccac aggcaccagg cguggaggcc     1080

aguggggccg gggaggcccg ggccagcacc gggagcucag auucuucccc ugguggccau     1140

gggacccagg ucaaugucac cugcaucgug aacgucugua gcagcucuga ccacagcuca     1200

cagugcuccu cccaagccag cuccacaaug ggagacacag auuccagccc cucggagucc     1260

ccgaaggacg agcagguccc cuucuccaag gaggaaugug ccuuucgguc acagcuggag     1320

acgccagaga cccugcuggg gagcaccgaa gagaagcccc ugccccuugg agugccugau     1380

gcugggauga agcccaguua aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  1476
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (wt)

<400>  1476
gggagaaagc uuaccaugcc ggucaugagg cuguucccuu gcuuccugca gcuccuggcc       60

gggcuggcgc ugccugcugu gcccccccag cagugggccu ugucugcugg gaacggcucg      120

ucagaggugg aagugguacc cuuccaggaa guguggggcc gcagcuacug ccgggcgcug      180

gagaggcugg uggacgucgu guccgaguac cccagcgagg uggagcacau guucagccca      240

uccugugucu cccugcugcg cugcaccggc ugcugcggcg augagaaucu gcacugugug      300

ccgguggaga cggccaaugu caccaugcag cuccuaaaga uccguucugg ggaccggccc      360

uccuacgugg agcugacguu cucucagcac guucgcugcg aaugccggcc ucugcgggag      420

aagaugaagc cggaaaggag gagacccaag ggcaggggga agaggaggag agagaagcag      480

agacccacag acugccaccu gugcggcgau gcuguucccc ggagguaagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  1477
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (wt)

<400>  1477
gggagaaagc uuaccaugac ggacagacag acagacaccg cccccagccc cagcuaccac       60

cuccuccccg gccggcggcg gacaguggac gcggcggcga gccgcgggca ggggccggag      120

cccgcgcccg gaggcggggu ggaggggguc ggggcucgcg gcgucgcacu gaaacuuuuc      180

guccaacuuc ugggcuguuc ucgcuucgga ggagccgugg uccgcgcggg ggaagccgag      240

ccgagcggag ccgcgagaag ugcuagcucg ggccgggagg agccgcagcc ggaggagggg      300

gaggaggaag aagagaagga agaggagagg gggccgcagu ggcgacucgg cgcucggaag      360

ccgggcucau ggacggguga ggcggcggug ugcgcagaca gugcuccagc cgcgcgcgcu      420

ccccaggccc uggcccgggc cucgggccgg ggaggaagag uagcucgccg aggcgccgag      480

gagagcgggc cgccccacag cccgagccgg agagggagcg cgagccgcgc cggccccggu      540

cgggccuccg aaaccaugaa cuuucugcug ucuugggugc auuggagccu ugccuugcug      600

cucuaccucc accaugccaa guggucccag gcugcaccca uggcagaagg aggagggcag      660

aaucaucacg aaguggugaa guucauggau gucuaucagc gcagcuacug ccauccaauc      720

gagacccugg uggacaucuu ccaggaguac ccugaugaga ucgaguacau cuucaagcca      780

uccugugugc cccugaugcg augcgggggc ugcugcaaug acgagggccu ggagugugug      840

cccacugagg aguccaacau caccaugcag auuaugcgga ucaaaccuca ccaaggccag      900

cacauaggag agaugagcuu ccuacagcac aacaaaugug aaugcagacc aaagaaagau      960

agagcaagac aagaaaaaaa aucaguucga ggaaagggaa aggggcaaaa acgaaagcgc     1020

aagaaauccc gguauaaguc cuggagcgug uacguuggug cccgcugcug ucuaaugccc     1080

uggagccucc cuggccccca ucccuguggg ccuugcucag agcggagaaa gcauuuguuu     1140

guacaagauc cgcagacgug uaaauguucc ugcaaaaaca cagacucgcg uugcaaggcg     1200

aggcagcuug aguuaaacga acguacuugc agaugugaca agccgaggcg gugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  1478
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (wt)

<400>  1478
gggagaaagc uuaccaugaa cuuucugcug ucuugggugc auuggagccu ugccuugcug       60

cucuaccucc accaugccaa guggucccag gcugcaccca uggcagaagg aggagggcag      120

aaucaucacg aaguggugaa guucauggau gucuaucagc gcagcuacug ccauccaauc      180

gagacccugg uggacaucuu ccaggaguac ccugaugaga ucgaguacau cuucaagcca      240

uccugugugc cccugaugcg augcgggggc ugcugcaaug acgagggccu ggagugugug      300

cccacugagg aguccaacau caccaugcag auuaugcgga ucaaaccuca ccaaggccag      360

cacauaggag agaugagcuu ccuacagcac aacaaaugug aaugcagacc aaagaaagau      420

agagcaagac aagaaaaaaa aucaguucga ggaaagggaa aggggcaaaa acgaaagcgc      480

aagaaauccc gguauaaguc cuggagcgug uacguuggug cccgcugcug ucuaaugccc      540

uggagccucc cuggccccca ucccuguggg ccuugcucag agcggagaaa gcauuuguuu      600

guacaagauc cgcagacgug uaaauguucc ugcaaaaaca cagacucgcg uugcaaggcg      660

aggcagcuug aguuaaacga acguacuugc agaugugaca agccgaggcg gugaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  1479
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (wt)

<400>  1479
gggagaaagc uuaccaugag cccucugcuc cgccgccugc ugcucgccgc acuccugcag       60

cuggcccccg cccaggcccc ugucucccag ccugaugccc cuggccacca gaggaaagug      120

gugucaugga uagaugugua uacucgcgcu accugccagc cccgggaggu gguggugccc      180

uugacugugg agcucauggg caccguggcc aaacagcugg ugcccagcug cgugacugug      240

cagcgcugug guggcugcug cccugacgau ggccuggagu gugugcccac ugggcagcac      300

caaguccgga ugcagauccu caugauccgg uacccgagca gucagcuggg ggagaugucc      360

cuggaagaac acagccagug ugaaugcaga ccuaaaaaaa aggacagugc ugugaagcca      420

gacagggcug ccacucccca ccaccguccc cagccccguu cuguuccggg cugggacucu      480

gcccccggag cacccucccc agcugacauc acccauccca cuccagcccc aggccccucu      540

gcccacgcug cacccagcac caccagcgcc cugacccccg gaccugccgc ugccgcugcc      600

gacgccgcag cuuccuccgu ugccaagggc ggggcuuagg gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  1480
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (wt)

<400>  1480
gggagaaagc uuaccaugca cuugcugggc uucuucucug uggcguguuc ucugcucgcc       60

gcugcgcugc ucccgggucc ucgcgaggcg cccgccgccg ccgccgccuu cgaguccgga      120

cucgaccucu cggacgcgga gcccgacgcg ggcgaggcca cggcuuaugc aagcaaagau      180

cuggaggagc aguuacgguc uguguccagu guagaugaac ucaugacugu acucuaccca      240

gaauauugga aaauguacaa gugucagcua aggaaaggag gcuggcaaca uaacagagaa      300

caggccaacc ucaacucaag gacagaagag acuauaaaau uugcugcagc acauuauaau      360

acagagaucu ugaaaaguau ugauaaugag uggagaaaga cucaaugcau gccacgggag      420

guguguauag auguggggaa ggaguuugga gucgcgacaa acaccuucuu uaaaccucca      480

uguguguccg ucuacagaug uggggguugc ugcaauagug aggggcugca gugcaugaac      540

accagcacga gcuaccucag caagacguua uuugaaauua cagugccucu cucucaaggc      600

cccaaaccag uaacaaucag uuuugccaau cacacuuccu gccgaugcau gucuaaacug      660

gauguuuaca gacaaguuca uuccauuauu agacguuccc ugccagcaac acuaccacag      720

ugucaggcag cgaacaagac cugccccacc aauuacaugu ggaauaauca caucugcaga      780

ugccuggcuc aggaagauuu uauguuuucc ucggaugcug gagaugacuc aacagaugga      840

uuccaugaca ucuguggacc aaacaaggag cuggaugaag agaccuguca gugugucugc      900

agagcggggc uucggccugc cagcugugga ccccacaaag aacuagacag aaacucaugc      960

cagugugucu guaaaaacaa acucuucccc agccaaugug gggccaaccg agaauuugau     1020

gaaaacacau gccagugugu auguaaaaga accugcccca gaaaucaacc ccuaaauccu     1080

ggaaaaugug ccugugaaug uacagaaagu ccacagaaau gcuuguuaaa aggaaagaag     1140

uuccaccacc aaacaugcag cuguuacaga cggccaugua cgaaccgcca gaaggcuugu     1200

gagccaggau uuucauauag ugaagaagug ugucguugug ucccuucaua uuggaaaaga     1260

ccacaaauga gcuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  1481
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (wt)

<400>  1481
gggagaaagc uuaccaugua cagagagugg guagugguga auguuuucau gauguuguac       60

guccagcugg ugcagggcuc caguaaugaa cauggaccag ugaagcgauc aucucagucc      120

acauuggaac gaucugaaca gcagaucagg gcugcuucua guuuggagga acuacuucga      180

auuacucacu cugaggacug gaagcugugg agaugcaggc ugaggcucaa aaguuuuacc      240

aguauggacu cucgcucagc aucccaucgg uccacuaggu uugcggcaac uuucuaugac      300

auugaaacac uaaaaguuau agaugaagaa uggcaaagaa cucagugcag cccuagagaa      360

acgugcgugg agguggccag ugagcugggg aagaguacca acacauucuu caagcccccu      420

ugugugaacg uguuccgaug ugguggcugu ugcaaugaag agagccuuau cuguaugaac      480

accagcaccu cguacauuuc caaacagcuc uuugagauau cagugccuuu gacaucagua      540

ccugaauuag ugccuguuaa aguugccaau cauacagguu guaagugcuu gccaacagcc      600

ccccgccauc cauacucaau uaucagaaga uccauccaga ucccugaaga agaucgcugu      660

ucccauucca agaaacucug uccuauugac augcuauggg auagcaacaa auguaaaugu      720

guuuugcagg aggaaaaucc acuugcugga acagaagacc acucucaucu ccaggaacca      780

gcucucugug ggccacacau gauguuugac gaagaucguu gcgagugugu cuguaaaaca      840

ccauguccca aagaucuaau ccagcacccc aaaaacugca guugcuuuga gugcaaagaa      900

agucuggaga ccugcugcca gaagcacaag cuauuucacc cagacaccug cagcugugag      960

gacagaugcc ccuuucauac cagaccaugu gcaaguggca aaacagcaug ugcaaagcau     1020

ugccgcuuuc caaaggagaa aagggcugcc caggggcccc acagccgaaa gaauccuuga     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  1482
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt1)

<400>  1482
gggagaaagc uuaccaugga cagcgacgag accggcuucg agcacuccgg gcugugggug       60

agcguccucg ccggccugcu gcucggggcc ugccaggccc accccauccc ggacuccagc      120

ccccugcugc aguucggcgg ccaggugcgc cagcgguacc ucuacaccga cgacgcccag      180

cagacggagg cccaccugga gauccgcgag gacgggaccg ugggcggggc cgccgaccag      240

ucccccgaga gccugcucca gcugaaggcg cugaagcccg gcgucaucca gauccucggg      300

gugaagaccu cccgguuccu gugccagcgc ccggacggcg cccuguacgg gagccuccac      360

uucgaccccg aggccugcuc cuuccgggag cugcugcucg aggacggcua caacguguac      420

cagagcgagg cccacggccu gccccugcac cuccccggga acaagucccc gcaccgcgac      480

cccgcgcccc ggggccccgc ccgcuuccug ccgcugcccg ggcucccgcc cgcccugccc      540

gagccgcccg gcauccuggc gccccagccg cccgacgucg gcagcuccga cccccucagc      600

augguggggc ccucccaggg ccggagcccc uccuacgcca gcugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  1483
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt1)

<400>  1483
gggagaaagc uuaccaugca cagcuucccg ccccugcucc ugcugcucuu cuggggcgug       60

gucucccaca gcuuccccgc cacccuggag acccaggagc aggacgugga ccuggugcag      120

aaguaccucg agaaguacua caaccugaag aacgacgggc gccaggucga gaagcggcgc      180

aacuccggcc ccguggugga gaagcugaag cagaugcagg aguucuucgg gcucaagguc      240

acgggcaagc ccgacgccga gacccugaag gugaugaagc agccgcggug cggggugccc      300

gacgucgcgc aguucgugcu gaccgagggc aacccccgcu gggagcagac ccaccucacg      360

uaccggaucg agaacuacac ccccgaccug ccgcgcgccg acguggacca cgccaucgag      420

aaggccuucc agcuguggag caacgucacc ccgcucaccu ucacgaaggu guccgagggc      480

caggccgaca ucaugaucag cuucgugcgg ggcgaccacc gcgacaacuc ccccuucgac      540

gggcccgggg gcaaccuggc gcacgccuuc cagccggggc ccggcaucgg cggggacgcc      600

cacuucgacg aggacgagcg guggaccaac aacuuccgcg aguacaaccu gcaccggguc      660

gccgcgcacg agcucggcca cagccugggg cugucccaca gcaccgacau cggcgcccuc      720

auguaccccu ccuacaccuu cagcggcgac gugcagcugg cccaggacga caucgacggg      780

auccaggcca ucuacggccg cucccagaac cccgugcagc cgaucgggcc ccagacgccc      840

aaggccugcg acagcaagcu gaccuucgac gcgaucacca ccauccgggg cgaggucaug      900

uucuucaagg accgcuucua caugcggacg aaccccuucu acccggaggu ggagcucaac      960

uucaucuccg uguucuggcc ccagcugccc aacgggcugg aggccgccua cgaguucgcc     1020

gaccgcgacg agguccgguu cuucaagggc aacaaguacu gggccgugca gggccagaac     1080

gugcuccacg gguaccccaa ggacaucuac agcuccuucg gcuucccgcg caccgucaag     1140

cacaucgacg cggcccugag cgaggagaac accgggaaga ccuacuucuu cguggccaac     1200

aaguacuggc gguacgacga guacaagcgc uccauggacc ccggcuaccc caagaugauc     1260

gcccacgacu uccccgggau cggccacaag gucgacgccg uguucaugaa ggacggcuuc     1320

uucuacuucu uccacgggac gcggcaguac aaguucgacc cgaagaccaa gcgcauccug     1380

acccuccaga aggcgaacag cugguucaac ugccgcaaga acugaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  1484
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt1)

<400>  1484
gggagaaagc uuaccaugca cagcuucccg ccccugcucc ugcugcucuu cuggggcgug       60

gucucccaca gcuucgugcu gaccgagggc aacccccgcu gggagcagac ccaccucacg      120

uaccggaucg agaacuacac ccccgaccug ccgcgcgccg acguggacca cgccaucgag      180

aaggccuucc agcuguggag caacgucacc ccgcucaccu ucacgaaggu guccgagggc      240

caggccgaca ucaugaucag cuucgugcgg ggcgaccacc gcgacaacuc ccccuucgac      300

gggcccgggg gcaaccuggc gcacgccuuc cagccggggc ccggcaucgg cggggacgcc      360

cacuucgacg aggacgagcg guggaccaac aacuuccgcg aguacaaccu gcaccggguc      420

gccgcgcacg agcucggcca cagccugggg cugucccaca gcaccgacau cggcgcccuc      480

auguaccccu ccuacaccuu cagcggcgac gugcagcugg cccaggacga caucgacggg      540

auccaggcca ucuacggccg cucccagaac cccgugcagc cgaucgggcc ccagacgccc      600

aaggccugcg acagcaagcu gaccuucgac gcgaucacca ccauccgggg cgaggucaug      660

uucuucaagg accgcuucua caugcggacg aaccccuucu acccggaggu ggagcucaac      720

uucaucuccg uguucuggcc ccagcugccc aacgggcugg aggccgccua cgaguucgcc      780

gaccgcgacg agguccgguu cuucaagggc aacaaguacu gggccgugca gggccagaac      840

gugcuccacg gguaccccaa ggacaucuac agcuccuucg gcuucccgcg caccgucaag      900

cacaucgacg cggcccugag cgaggagaac accgggaaga ccuacuucuu cguggccaac      960

aaguacuggc gguacgacga guacaagcgc uccauggacc ccggcuaccc caagaugauc     1020

gcccacgacu uccccgggau cggccacaag gucgacgccg uguucaugaa ggacggcuuc     1080

uucuacuucu uccacgggac gcggcaguac aaguucgacc cgaagaccaa gcgcauccug     1140

acccuccaga aggcgaacag cugguucaac ugccgcaaga acugaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  1485
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt1)

<400>  1485
gggagaaagc uuaccaugaa gaagaacauc cugaagaucc ucauggacag cuacuccaag       60

gagagcaaga uccagaccgu gcgccggguc accuccguga gccugcuggc cguguaccuc      120

acgaugaaca ccuccagccu gguccuggcc aagcccaucg agaacaccaa cgacaccucc      180

aucaagaacg uggagaagcu ccgcaacgcg cccaacgagg agaacagcaa gaagguggag      240

gacuccaaga acgacaaggu cgagcacgug aagaacaucg aggaggccaa gguggagcag      300

gucgcccccg aggugaagag caaguccacg cugcggagcg ccuccaucgc caacaccaac      360

agcgagaagu acgacuucga guaccugaac ggccucuccu acaccgagcu gaccaaccug      420

aucaagaaca ucaaguggaa ccagaucaac gggcucuuca acuacagcac gggcucccag      480

aaguucuucg gggacaagaa ccgcgugcag gcgaucauca acgcccugca ggagagcggc      540

cggaccuaca ccgccaacga caugaagggg aucgagaccu ucacggaggu ccugcgcgcc      600

ggcuucuacc ucggcuacua caacgacggg cuguccuacc ugaacgaccg gaacuuccag      660

gacaagugca uccccgcgau gaucgccauc cagaagaacc ccaacuucaa gcucggcacc      720

gccgugcagg acgaggugau caccagccug gggaagcuga ucggcaacgc cagcgccaac      780

gcggaggucg ugaacaacug cgugccgguc cucaagcagu uccgcgagaa ccugaaccag      840

uacgcccccg acuacgugaa ggggaccgcc gugaacgagc ugaucaaggg caucgaguuc      900

gacuucuccg gcgccgccua cgagaaggac gucaagacga ugcccuggua cgggaagauc      960

gaccccuuca ucaacgagcu caaggcgcug ggccuguacg ggaacaucac cagcgccacc     1020

gagugggccu ccgacguggg caucuacuac cucagcaagu ucggccugua cuccaccaac     1080

cggaacgaca ucgugcagag ccuggagaag gccgucgaca uguacaagua cgggaagauc     1140

gccuucgugg cgauggagcg caucacgugg gacuacgacg gcaucggguc caacggcaag     1200

aaggucgacc acgacaaguu ccucgacgac gccgagaagc acuaccugcc gaagaccuac     1260

accuucgaca acgggaccuu caucauccgg gccggcgaca aggugagcga ggagaagauc     1320

aagcgccugu acugggccuc ccgggaggug aagagccagu uccaccgcgu cgugggcaac     1380

gacaaggccc ucgagguggg gaacgcggac gacguccuga cgaugaagau cuucaacucc     1440

cccgaggagu acaaguucaa caccaacauc aacggcguga gcaccgacaa cgggggccug     1500

uacaucgagc cgcgggggac cuucuacacg uacgagcgca ccccgcagca guccaucuuc     1560

agccucgagg agcuguuccg gcacgaguac acccacuacc ugcaggcccg cuaccucgug     1620

gacggccugu ggggccaggg gccguucuac gagaagaacc ggcugaccug guucgacgag     1680

ggcacggccg aguucuucgc cggguccacc cgcaccagcg gcguccuccc ccggaagucc     1740

auccuggggu accuggcgaa ggacaaggug gaccaccgcu acagccucaa gaagacccug     1800

aacuccggcu acgacgacag cgacuggaug uucuacaacu acggcuucgc cguggcccac     1860

uaccuguacg agaaggacau gcccacguuc aucaagauga acaaggccau ccugaacacc     1920

gacgucaaga gcuacgacga gaucaucaag aagcucuccg acgacgccaa caagaacacc     1980

gaguaccaga accacaucca ggagcuggcg gacaaguacc agggggccgg caucccccug     2040

gugagcgacg acuaccucaa ggaccacggg uacaagaagg ccuccgaggu guacagcgag     2100

aucuccaagg ccgccagccu gaccaacacc uccgucacgg cggagaagag ccaguacuuc     2160

aacaccuuca cccugcgcgg caccuacacg ggcgagaccu ccaaggggga guucaaggac     2220

ugggacgaga ugagcaagaa gcucgacggc acccuggagu cccuggccaa gaacagcugg     2280

uccggguaca agacccucac ggccuacuuc accaacuacc gggugaccag cgacaacaag     2340

gugcaguacg acgucguguu ccacggcgug cugaccgaca acgccgacau cuccaacaac     2400

aaggccccga ucgcgaaggu cacggggccc agcaccggcg ccgugggccg caacaucgag     2460

uucuccggga aggacagcaa ggacgaggac ggcaagaucg ugagcuacga cugggacuuc     2520

ggggacggcg ccaccucccg ggggaagaac agcguccacg ccuacaagaa ggcgggcacc     2580

uacaacguga cgcugaaggu gaccgacgac aagggcgcca ccgccaccga guccuucacg     2640

aucgagauca agaacgagga caccaccacc cccaucacga aggagaugga gcccaacgac     2700

gacaucaagg aggccaacgg gccgaucguc gagggcguga ccgugaaggg ggaccucaac     2760

ggcagcgacg acgccgacac cuucuacuuc gacgucaagg aggacgggga cgugaccauc     2820

gagcugcccu acuccggcag cuccaacuuc acguggcugg uguacaagga gggcgacgac     2880

cagaaccaca ucgcgagcgg gaucgacaag aacaacucca aggucggcac cuucaagagc     2940

accaaggggc gccacuacgu guucaucuac aagcacgacu ccgccagcaa caucuccuac     3000

agccucaaca ucaagggccu ggggaacgag aagcugaagg agaaggagaa caacgacucc     3060

agcgacaagg ccaccgugau ccccaacuuc aacacgacca ugcagggcuc ccuccugggc     3120

gacgacagcc gggacuacua cuccuucgag gucaaggagg agggggaggu gaacaucgag     3180

cuggacaaga aggacgaguu cggcgugacc uggacccucc accccgagag caacaucaac     3240

gaccgcauca cguacgggca ggucgacggc aacaagguga gcaacaaggu gaagcugcgg     3300

ccgggcaagu acuaccugcu cgucuacaag uacuccggga gcggcaacua cgagcugcgc     3360

gugaacaagu gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  1486
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt1)

<400>  1486
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuccu guucuccagc       60

gccuacucca ucgccaacac caacagcgag aaguacgacu ucgaguaccu gaacggccuc      120

uccuacaccg agcugaccaa ccugaucaag aacaucaagu ggaaccagau caacgggcuc      180

uucaacuaca gcacgggcuc ccagaaguuc uucggggaca agaaccgcgu gcaggcgauc      240

aucaacgccc ugcaggagag cggccggacc uacaccgcca acgacaugaa ggggaucgag      300

accuucacgg agguccugcg cgccggcuuc uaccucggcu acuacaacga cgggcugucc      360

uaccugaacg accggaacuu ccaggacaag ugcauccccg cgaugaucgc cauccagaag      420

aaccccaacu ucaagcucgg caccgccgug caggacgagg ugaucaccag ccuggggaag      480

cugaucggca acgccagcgc caacgcggag gucgugaaca acugcgugcc gguccucaag      540

caguuccgcg agaaccugaa ccaguacgcc cccgacuacg ugaaggggac cgccgugaac      600

gagcugauca agggcaucga guucgacuuc uccggcgccg ccuacgagaa ggacgucaag      660

acgaugcccu gguacgggaa gaucgacccc uucaucaacg agcucaaggc gcugggccug      720

uacgggaaca ucaccagcgc caccgagugg gccuccgacg ugggcaucua cuaccucagc      780

aaguucggcc uguacuccac caaccggaac gacaucgugc agagccugga gaaggccguc      840

gacauguaca aguacgggaa gaucgccuuc guggcgaugg agcgcaucac gugggacuac      900

gacggcaucg gguccaacgg caagaagguc gaccacgaca aguuccucga cgacgccgag      960

aagcacuacc ugccgaagac cuacaccuuc gacaacggga ccuucaucau ccgggccggc     1020

gacaagguga gcgaggagaa gaucaagcgc cuguacuggg ccucccggga ggugaagagc     1080

caguuccacc gcgucguggg caacgacaag gcccucgagg uggggaacgc ggacgacguc     1140

cugacgauga agaucuucaa cucccccgag gaguacaagu ucaacaccaa caucaacggc     1200

gugagcaccg acaacggggg ccuguacauc gagccgcggg ggaccuucua cacguacgag     1260

cgcaccccgc agcaguccau cuucagccuc gaggagcugu uccggcacga guacacccac     1320

uaccugcagg cccgcuaccu cguggacggc cuguggggcc aggggccguu cuacgagaag     1380

aaccggcuga ccugguucga cgagggcacg gccgaguucu ucgccggguc cacccgcacc     1440

agcggcgucc ucccccggaa guccauccug ggguaccugg cgaaggacaa gguggaccac     1500

cgcuacagcc ucaagaagac ccugaacucc ggcuacgacg acagcgacug gauguucuac     1560

aacuacggcu ucgccguggc ccacuaccug uacgagaagg acaugcccac guucaucaag     1620

augaacaagg ccauccugaa caccgacguc aagagcuacg acgagaucau caagaagcuc     1680

uccgacgacg ccaacaagaa caccgaguac cagaaccaca uccaggagcu ggcggacaag     1740

uaccaggggg ccggcauccc ccuggugagc gacgacuacc ucaaggacca cggguacaag     1800

aaggccuccg agguguacag cgagaucucc aaggccgcca gccugaccaa caccuccguc     1860

acggcggaga agagccagua cuucaacacc uucacccugc gcggcaccua cacgggcgag     1920

accuccaagg gggaguucaa ggacugggac gagaugagca agaagcucga cggcacccug     1980

gagucccugg ccaagaacag cugguccggg uacaagaccc ucacggccua cuucaccaac     2040

uaccggguga ccagcgacaa caaggugcag uacgacgucg uguuccacgg cgugcugacc     2100

gacaacgccg acaucuccaa caacaaggcc ccgaucgcga aggucacggg gcccagcacc     2160

ggcgccgugg gccgcaacau cgaguucucc gggaaggaca gcaaggacga ggacggcaag     2220

aucgugagcu acgacuggga cuucggggac ggcgccaccu cccgggggaa gaacagcguc     2280

cacgccuaca agaaggcggg caccuacaac gugacgcuga aggugaccga cgacaagggc     2340

gccaccgcca ccgaguccuu cacgaucgag aucaagaacg aggacaccac cacccccauc     2400

acgaaggaga uggagcccaa cgacgacauc aaggaggcca acgggccgau cgucgagggc     2460

gugaccguga agggggaccu caacggcagc gacgacgccg acaccuucua cuucgacguc     2520

aaggaggacg gggacgugac caucgagcug cccuacuccg gcagcuccaa cuucacgugg     2580

cugguguaca aggagggcga cgaccagaac cacaucgcga gcgggaucga caagaacaac     2640

uccaaggucg gcaccuucaa gagcaccaag gggcgccacu acguguucau cuacaagcac     2700

gacuccgcca gcaacaucuc cuacagccuc aacaucaagg gccuggggaa cgagaagcug     2760

aaggagaagg agaacaacga cuccagcgac aaggccaccg ugauccccaa cuucaacacg     2820

accaugcagg gcucccuccu gggcgacgac agccgggacu acuacuccuu cgaggucaag     2880

gaggaggggg aggugaacau cgagcuggac aagaaggacg aguucggcgu gaccuggacc     2940

cuccaccccg agagcaacau caacgaccgc aucacguacg ggcaggucga cggcaacaag     3000

gugagcaaca aggugaagcu gcggccgggc aaguacuacc ugcucgucua caaguacucc     3060

gggagcggca acuacgagcu gcgcgugaac aagugaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  1487
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt1)

<400>  1487
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuccu guucuccagc       60

gccuacucca ugaagaagaa cauccugaag auccucaugg acagcuacuc caaggagagc      120

aagauccaga ccgugcgccg ggucaccucc gugagccugc uggccgugua ccucacgaug      180

aacaccucca gccugguccu ggccaagccc aucgagaaca ccaacgacac cuccaucaag      240

aacguggaga agcuccgcaa cgcgcccaac gaggagaaca gcaagaaggu ggaggacucc      300

aagaacgaca aggucgagca cgugaagaac aucgaggagg ccaaggugga gcaggucgcc      360

cccgagguga agagcaaguc cacgcugcgg agcgccuccc gccggcgccg gaagcgcauc      420

gccaacacca acagcgagaa guacgacuuc gaguaccuga acggccucuc cuacaccgag      480

cugaccaacc ugaucaagaa caucaagugg aaccagauca acgggcucuu caacuacagc      540

acgggcuccc agaaguucuu cggggacaag aaccgcgugc aggcgaucau caacgcccug      600

caggagagcg gccggaccua caccgccaac gacaugaagg ggaucgagac cuucacggag      660

guccugcgcg ccggcuucua ccucggcuac uacaacgacg ggcuguccua ccugaacgac      720

cggaacuucc aggacaagug cauccccgcg augaucgcca uccagaagaa ccccaacuuc      780

aagcucggca ccgccgugca ggacgaggug aucaccagcc uggggaagcu gaucggcaac      840

gccagcgcca acgcggaggu cgugaacaac ugcgugccgg uccucaagca guuccgcgag      900

aaccugaacc aguacgcccc cgacuacgug aaggggaccg ccgugaacga gcugaucaag      960

ggcaucgagu ucgacuucuc cggcgccgcc uacgagaagg acgucaagac gaugcccugg     1020

uacgggaaga ucgaccccuu caucaacgag cucaaggcgc ugggccugua cgggaacauc     1080

accagcgcca ccgagugggc cuccgacgug ggcaucuacu accucagcaa guucggccug     1140

uacuccacca accggaacga caucgugcag agccuggaga aggccgucga cauguacaag     1200

uacgggaaga ucgccuucgu ggcgauggag cgcaucacgu gggacuacga cggcaucggg     1260

uccaacggca agaaggucga ccacgacaag uuccucgacg acgccgagaa gcacuaccug     1320

ccgaagaccu acaccuucga caacgggacc uucaucaucc gggccggcga caaggugagc     1380

gaggagaaga ucaagcgccu guacugggcc ucccgggagg ugaagagcca guuccaccgc     1440

gucgugggca acgacaaggc ccucgaggug gggaacgcgg acgacguccu gacgaugaag     1500

aucuucaacu cccccgagga guacaaguuc aacaccaaca ucaacggcgu gagcaccgac     1560

aacgggggcc uguacaucga gccgcggggg accuucuaca cguacgagcg caccccgcag     1620

caguccaucu ucagccucga ggagcuguuc cggcacgagu acacccacua ccugcaggcc     1680

cgcuaccucg uggacggccu guggggccag gggccguucu acgagaagaa ccggcugacc     1740

ugguucgacg agggcacggc cgaguucuuc gccgggucca cccgcaccag cggcguccuc     1800

ccccggaagu ccauccuggg guaccuggcg aaggacaagg uggaccaccg cuacagccuc     1860

aagaagaccc ugaacuccgg cuacgacgac agcgacugga uguucuacaa cuacggcuuc     1920

gccguggccc acuaccugua cgagaaggac augcccacgu ucaucaagau gaacaaggcc     1980

auccugaaca ccgacgucaa gagcuacgac gagaucauca agaagcucuc cgacgacgcc     2040

aacaagaaca ccgaguacca gaaccacauc caggagcugg cggacaagua ccagggggcc     2100

ggcauccccc uggugagcga cgacuaccuc aaggaccacg gguacaagaa ggccuccgag     2160

guguacagcg agaucuccaa ggccgccagc cugaccaaca ccuccgucac ggcggagaag     2220

agccaguacu ucaacaccuu cacccugcgc ggcaccuaca cgggcgagac cuccaagggg     2280

gaguucaagg acugggacga gaugagcaag aagcucgacg gcacccugga gucccuggcc     2340

aagaacagcu gguccgggua caagacccuc acggccuacu ucaccaacua ccgggugacc     2400

agcgacaaca aggugcagua cgacgucgug uuccacggcg ugcugaccga caacgccgac     2460

aucuccaaca acaaggcccc gaucgcgaag gucacggggc ccagcaccgg cgccgugggc     2520

cgcaacaucg aguucuccgg gaaggacagc aaggacgagg acggcaagau cgugagcuac     2580

gacugggacu ucggggacgg cgccaccucc cgggggaaga acagcgucca cgccuacaag     2640

aaggcgggca ccuacaacgu gacgcugaag gugaccgacg acaagggcgc caccgccacc     2700

gaguccuuca cgaucgagau caagaacgag gacaccacca cccccaucac gaaggagaug     2760

gagcccaacg acgacaucaa ggaggccaac gggccgaucg ucgagggcgu gaccgugaag     2820

ggggaccuca acggcagcga cgacgccgac accuucuacu ucgacgucaa ggaggacggg     2880

gacgugacca ucgagcugcc cuacuccggc agcuccaacu ucacguggcu gguguacaag     2940

gagggcgacg accagaacca caucgcgagc gggaucgaca agaacaacuc caaggucggc     3000

accuucaaga gcaccaaggg gcgccacuac guguucaucu acaagcacga cuccgccagc     3060

aacaucuccu acagccucaa caucaagggc cuggggaacg agaagcugaa ggagaaggag     3120

aacaacgacu ccagcgacaa ggccaccgug auccccaacu ucaacacgac caugcagggc     3180

ucccuccugg gcgacgacag ccgggacuac uacuccuucg aggucaagga ggagggggag     3240

gugaacaucg agcuggacaa gaaggacgag uucggcguga ccuggacccu ccaccccgag     3300

agcaacauca acgaccgcau cacguacggg caggucgacg gcaacaaggu gagcaacaag     3360

gugaagcugc ggccgggcaa guacuaccug cucgucuaca aguacuccgg gagcggcaac     3420

uacgagcugc gcgugaacaa gugaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  1488
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt1)

<400>  1488
gggagaaagc uuaccaugaa cuuccugaag aucauccuca accgcggcaa gaccaugaag       60

cggaagugcc ugagcaagcg ccugaugcuc gccaucacca uggccacgau cuucaccgug      120

aacuccaccc ugcccaucua cgcggccguc gacaagaaca acgccaccgc cgccgugcag      180

aacgagagca agcgguacac gguguccuac cugaagaccc ucaacuacua cgaccugguc      240

gaccugcucg ugaagaccga gaucgagaac cugccggacc uguuccagua cagcuccgac      300

gcgaaggagu ucuacgggaa caagacccgc augagcuuca ucauggacga gaucggccgg      360

cgcgcgcccc aguacacgga gaucgaccac aaggggaucc ccacccucgu ggaggucgug      420

cgggccggcu ucuaccuggg guuccacaac aaggagcuga acgagaucaa caagcgcucc      480

uucaaggagc gggugauccc cagcauccuc gccauccaga agaacccgaa cuucaagcug      540

ggcaccgagg uccaggacaa gaucgugucc gccaccggcc ugcucgccgg gaacgagacg      600

gccccgcccg agguggucaa caacuucacc cccauccugc aggacugcau caagaacauc      660

gaccgcuacg cccuggacga ccucaagagc aaggcccugu ucaacgugcu ggcggccccg      720

accuacgaca ucaccgagua ccuccgggcc acgaaggaga agcccgagaa cacccccugg      780

uacggcaaga ucgacggguu caucaacgag cugaagaagc uggcccucua cggcaagauc      840

aacgacaaca acuccuggau caucgacaac gggaucuacc acaucgcgcc ccugggcaag      900

cugcacagca acaacaagau cggcaucgag acccucaccg aggugaugaa ggucuacccg      960

uaccugucca ugcagcaccu ccagagcgcc gaccagauca agcgccacua cgacuccaag     1020

gacgccgagg ggaacaagau cccccuggac aaguucaaga aggagggcaa ggagaaguac     1080

ugccccaaga cguacaccuu cgacgacggg aaggugauca ucaaggccgg cgcccgggug     1140

gaggaggaga aggucaagcg ccuguacugg gccagcaagg aggugaacuc ccaguucuuc     1200

cggguguacg gcaucgacaa gccccuggag gaggggaacc cggacgacau ccucaccaug     1260

gucaucuaca acagccccga ggaguacaag cugaacuccg ugcuguacgg cuacgacacc     1320

aacaacgggg gcauguacau cgagcccgag gggacguucu ucaccuacga gcgcgaggcg     1380

caggagagca ccuacacccu cgaggagcug uuccggcacg aguacacgca cuaccugcag     1440

ggccgcuacg ccgugcccgg ccaguggggg cggaccaagc ucuacgacaa cgaccgccug     1500

accugguacg aggagggcgg ggccgagcug uucgccggca gcacccggac guccgggauc     1560

cucccgcgca agagcaucgu cuccaacauc cacaacacca cccgcaacaa ccgguacaag     1620

cugagcgaca ccgugcacuc caaguacggc gccagcuucg aguucuacaa cuacgcgugc     1680

auguucaugg acuacaugua caacaaggac augggcaucc ugaacaagcu caacgaccug     1740

gccaagaaca acgacgucga cggguacgac aacuacaucc gcgaccuguc cagcaacuac     1800

gcccugaacg acaaguacca ggaccacaug caggagcgga ucgacaacua cgagaaccuc     1860

acggugcccu ucguggccga cgacuaccug guccgccacg cguacaagaa ccccaacgag     1920

aucuacuccg agaucagcga gguggccaag cugaaggacg ccaaguccga ggugaagaag     1980

ucccaguacu ucagcaccuu cacccuccgg ggcagcuaca ccgggggcgc cuccaagggg     2040

aagcuggagg accagaaggc caugaacaag uucaucgacg acagccugaa gaagcucgac     2100

accuacuccu ggagcggcua caagacgcug accgcguacu ucaccaacua caaggucgac     2160

uccagcaacc gcgugaccua cgacgugguc uuccacggcu accugcccaa cgagggggac     2220

agcaagaacu cccucccgua cggcaagauc aacgggacgu acaagggcac cgagaaggag     2280

aagaucaagu ucagcuccga gggcagcuuc gaccccgacg ggaagaucgu guccuacgag     2340

ugggacuucg gcgacgggaa caagagcaac gaggagaacc ccgagcacuc cuacgacaag     2400

gugggcaccu acaccgucaa gcugaaggug acggacgaca agggggagag cuccgugagc     2460

accaccaccg ccgagaucaa ggaccugucc gagaacaagc uccccgucau cuacaugcac     2520

gugcccaaga gcggcgcccu gaaccagaag guggucuucu acggcaaggg gacguacgac     2580

cccgacggcu ccaucgccgg guaccagugg gacuucggcg acgggagcga cuucuccagc     2640

gagcagaacc ccucccacgu guacaccaag aagggcgagu acaccgugac ccugcggguc     2700

auggacagca gcggccagau guccgagaag acgaugaaga ucaagaucac cgacccggug     2760

uaccccaucg ggaccgagaa ggagcccaac aacagcaagg agaccgccuc cggccccauc     2820

gugccgggga uccccgucag cggcacgauc gagaacaccu ccgaccagga cuacuucuac     2880

uucgacguga ucacccccgg ggaggugaag aucgacauca acaagcucgg cuacggcggg     2940

gcgaccuggg ucguguacga cgagaacaac aacgccguga gcuacgccac ggacgacggc     3000

cagaaccugu ccgggaaguu caaggccgac aagcccggcc gcuacuacau ccaccuguac     3060

auguucaacg ggagcuacau gccguaccgg aucaacaucg agggcuccgu cggccgcuga     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  1489
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt1)

<400>  1489
gggagaaagc uuaccaugaa gcgcaagugc cugagcaagc ggcucaugcu ggccaucacc       60

auggccacca ucuucacggu gaacuccacc cugcccaucu acgcggccgu cgacaagaac      120

aacgccaccg ccgccgugca gaacgagagc aagcgcuaca ccguguccua ccucaagacg      180

cugaacuacu acgaccuggu cgaccuccug gugaagaccg agaucgagaa ccugcccgac      240

cucuuccagu acagcuccga cgcgaaggag uucuacggca acaagacccg gaugagcuuc      300

aucauggacg agaucgggcg ccgggccccg caguacaccg agaucgacca caagggcauc      360

cccacgcugg uggaggucgu gcgcgccggg uucuaccugg gcuuccacaa caaggagcuc      420

aacgagauca acaagcgguc cuucaaggag cgcgugaucc ccagcauccu ggccauccag      480

aagaacccga acuucaagcu ggggaccgag guccaggaca agaucguguc cgcgaccggc      540

cuccuggccg gcaacgagac cgccccgccc gaggugguca acaacuucac gcccauccug      600

caggacugca ucaagaacau cgaccgguac gcccucgacg accugaagag caaggcccug      660

uucaacgugc ucgcggcccc gaccuacgac aucaccgagu accugcgcgc caccaaggag      720

aagcccgaga acacgccgug guacgggaag aucgacggcu ucaucaacga gcugaagaag      780

cucgcccugu acgggaagau caacgacaac aacuccugga ucaucgacaa cggcaucuac      840

cacaucgccc cccuggggaa gcuccacagc aacaacaaga ucggcaucga gacccugacc      900

gaggugauga aggucuaccc guaccugucc augcagcacc uccagagcgc ggaccagauc      960

aagcggcacu acgacuccaa ggacgccgag ggcaacaaga ucccccugga caaguucaag     1020

aaggagggga aggagaagua cugccccaag accuacacgu ucgacgacgg caaggugauc     1080

aucaaggccg gggcccgcgu ggaggaggag aaggucaagc ggcuguacug ggccagcaag     1140

gaggugaacu cccaguucuu ccgcguguac ggcaucgaca agccccucga ggagggcaac     1200

ccggacgaca uccugaccau ggucaucuac aacagccccg aggaguacaa gcugaacucc     1260

gugcucuacg gguacgacac caacaacggc gggauguaca ucgagcccga gggcaccuuc     1320

uucacguacg agcgggaggc gcaggagagc accuacaccc uggaggagcu guuccgccac     1380

gaguacaccc acuaccucca ggggcgguac gccgugcccg gccagugggg ccgcacgaag     1440

cuguacgaca acgaccggcu gaccugguac gaggagggcg gcgccgagcu cuucgccggg     1500

agcacccgca ccuccgggau ccugccgcgg aagagcaucg ucuccaacau ccacaacacg     1560

acccgcaaca accgcuacaa gcugagcgac accgugcacu ccaaguacgg ggccagcuuc     1620

gaguucuaca acuacgcgug cauguucaug gacuacaugu acaacaagga caugggcauc     1680

cucaacaagc ugaacgaccu ggccaagaac aacgacgucg acggcuacga caacuacauc     1740

cgggaccugu ccagcaacua cgcccucaac gacaaguacc aggaccacau gcaggagcgc     1800

aucgacaacu acgagaaccu gaccgugccc uucguggccg acgacuaccu gguccggcac     1860

gcguacaaga accccaacga gaucuacucc gagaucagcg agguggccaa gcucaaggac     1920

gccaaguccg aggugaagaa gagccaguac uucuccacgu ucacccugcg cgggagcuac     1980

accggcgggg ccuccaaggg caagcuggag gaccagaagg ccaugaacaa guucaucgac     2040

gacagccuca agaagcugga caccuacucc uggagcgggu acaagacccu gacggcguac     2100

uucaccaacu acaaggucga cuccagcaac cgggugaccu acgacguggu cuuccacggc     2160

uaccucccca acgagggcga cagcaagaac ucccugccgu acgggaagau caacggcacc     2220

uacaagggga cggagaagga gaagaucaag uucagcuccg agggcagcuu cgaccccgac     2280

ggcaagaucg uguccuacga gugggacuuc ggggacggca acaagagcaa cgaggagaac     2340

cccgagcacu ccuacgacaa gguggggacc uacaccguca agcugaaggu gaccgacgac     2400

aagggcgaga gcuccgugag cacgaccacc gccgagauca aggaccucuc cgagaacaag     2460

cugcccguca ucuacaugca cgugccgaag agcggggccc ugaaccagaa gguggucuuc     2520

uacggcaagg gcaccuacga ccccgacggg uccaucgccg gcuaccagug ggacuucggg     2580

gacggcagcg acuucuccag cgagcagaac cccucccacg uguacacgaa gaagggggag     2640

uacaccguga cccuccgcgu cauggacagc agcggccaga uguccgagaa gaccaugaag     2700

aucaagauca cggacccggu guaccccauc ggcaccgaga aggagcccaa caacagcaag     2760

gagaccgccu ccgggcccau cgugccgggc auccccguca gcgggaccau cgagaacacg     2820

uccgaccagg acuacuucua cuucgacgug aucacccccg gcgaggugaa gaucgacauc     2880

aacaagcugg gguacggcgg cgcgaccugg gucguguacg acgagaacaa caacgccgug     2940

agcuacgcca ccgacgacgg gcagaaccug uccggcaagu ucaaggccga caagcccggg     3000

cgguacuaca uccaccucua cauguucaac ggcagcuaca ugccguaccg caucaacauc     3060

gagggguccg ucggccggug aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  1490
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt1)

<400>  1490
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuccu guucuccagc       60

gccuacuccg ugcagaacga gagcaagcgc uacaccgugu ccuaccucaa gacgcugaac      120

uacuacgacc uggucgaccu ccuggugaag accgagaucg agaaccugcc cgaccucuuc      180

caguacagcu ccgacgcgaa ggaguucuac ggcaacaaga cccggaugag cuucaucaug      240

gacgagaucg ggcgccgggc cccgcaguac accgagaucg accacaaggg cauccccacg      300

cugguggagg ucgugcgcgc cggguucuac cugggcuucc acaacaagga gcucaacgag      360

aucaacaagc gguccuucaa ggagcgcgug auccccagca uccuggccau ccagaagaac      420

ccgaacuuca agcuggggac cgagguccag gacaagaucg uguccgcgac cggccuccug      480

gccggcaacg agaccgcccc gcccgaggug gucaacaacu ucacgcccau ccugcaggac      540

ugcaucaaga acaucgaccg guacgcccuc gacgaccuga agagcaaggc ccuguucaac      600

gugcucgcgg ccccgaccua cgacaucacc gaguaccugc gcgccaccaa ggagaagccc      660

gagaacacgc cgugguacgg gaagaucgac ggcuucauca acgagcugaa gaagcucgcc      720

cuguacggga agaucaacga caacaacucc uggaucaucg acaacggcau cuaccacauc      780

gccccccugg ggaagcucca cagcaacaac aagaucggca ucgagacccu gaccgaggug      840

augaaggucu acccguaccu guccaugcag caccuccaga gcgcggacca gaucaagcgg      900

cacuacgacu ccaaggacgc cgagggcaac aagauccccc uggacaaguu caagaaggag      960

gggaaggaga aguacugccc caagaccuac acguucgacg acggcaaggu gaucaucaag     1020

gccggggccc gcguggagga ggagaagguc aagcggcugu acugggccag caaggaggug     1080

aacucccagu ucuuccgcgu guacggcauc gacaagcccc ucgaggaggg caacccggac     1140

gacauccuga ccauggucau cuacaacagc cccgaggagu acaagcugaa cuccgugcuc     1200

uacggguacg acaccaacaa cggcgggaug uacaucgagc ccgagggcac cuucuucacg     1260

uacgagcggg aggcgcagga gagcaccuac acccuggagg agcuguuccg ccacgaguac     1320

acccacuacc uccaggggcg guacgccgug cccggccagu ggggccgcac gaagcuguac     1380

gacaacgacc ggcugaccug guacgaggag ggcggcgccg agcucuucgc cgggagcacc     1440

cgcaccuccg ggauccugcc gcggaagagc aucgucucca acauccacaa cacgacccgc     1500

aacaaccgcu acaagcugag cgacaccgug cacuccaagu acggggccag cuucgaguuc     1560

uacaacuacg cgugcauguu cauggacuac auguacaaca aggacauggg cauccucaac     1620

aagcugaacg accuggccaa gaacaacgac gucgacggcu acgacaacua cauccgggac     1680

cuguccagca acuacgcccu caacgacaag uaccaggacc acaugcagga gcgcaucgac     1740

aacuacgaga accugaccgu gcccuucgug gccgacgacu accugguccg gcacgcguac     1800

aagaacccca acgagaucua cuccgagauc agcgaggugg ccaagcucaa ggacgccaag     1860

uccgagguga agaagagcca guacuucucc acguucaccc ugcgcgggag cuacaccggc     1920

ggggccucca agggcaagcu ggaggaccag aaggccauga acaaguucau cgacgacagc     1980

cucaagaagc uggacaccua cuccuggagc ggguacaaga cccugacggc guacuucacc     2040

aacuacaagg ucgacuccag caaccgggug accuacgacg uggucuucca cggcuaccuc     2100

cccaacgagg gcgacagcaa gaacucccug ccguacggga agaucaacgg caccuacaag     2160

gggacggaga aggagaagau caaguucagc uccgagggca gcuucgaccc cgacggcaag     2220

aucguguccu acgaguggga cuucggggac ggcaacaaga gcaacgagga gaaccccgag     2280

cacuccuacg acaagguggg gaccuacacc gucaagcuga aggugaccga cgacaagggc     2340

gagagcuccg ugagcacgac caccgccgag aucaaggacc ucuccgagaa caagcugccc     2400

gucaucuaca ugcacgugcc gaagagcggg gcccugaacc agaagguggu cuucuacggc     2460

aagggcaccu acgaccccga cggguccauc gccggcuacc agugggacuu cggggacggc     2520

agcgacuucu ccagcgagca gaaccccucc cacguguaca cgaagaaggg ggaguacacc     2580

gugacccucc gcgucaugga cagcagcggc cagauguccg agaagaccau gaagaucaag     2640

aucacggacc cgguguaccc caucggcacc gagaaggagc ccaacaacag caaggagacc     2700

gccuccgggc ccaucgugcc gggcaucccc gucagcggga ccaucgagaa cacguccgac     2760

caggacuacu ucuacuucga cgugaucacc cccggcgagg ugaagaucga caucaacaag     2820

cugggguacg gcggcgcgac cugggucgug uacgacgaga acaacaacgc cgugagcuac     2880

gccaccgacg acgggcagaa ccuguccggc aaguucaagg ccgacaagcc cgggcgguac     2940

uacauccacc ucuacauguu caacggcagc uacaugccgu accgcaucaa caucgagggg     3000

uccgucggcc ggugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1491
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt1)

<400>  1491
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuccu guucuccagc       60

gccuacucca ugaagcgcaa gugccugagc aagcggcuca ugcuggccau caccauggcc      120

accaucuuca cggugaacuc cacccugccc aucuacgcgg ccgucgacaa gaacaacgcc      180

accgccgccc gccggcgccg gaagcgcgug cagaacgaga gcaagcgcua caccgugucc      240

uaccucaaga cgcugaacua cuacgaccug gucgaccucc uggugaagac cgagaucgag      300

aaccugcccg accucuucca guacagcucc gacgcgaagg aguucuacgg caacaagacc      360

cggaugagcu ucaucaugga cgagaucggg cgccgggccc cgcaguacac cgagaucgac      420

cacaagggca uccccacgcu gguggagguc gugcgcgccg gguucuaccu gggcuuccac      480

aacaaggagc ucaacgagau caacaagcgg uccuucaagg agcgcgugau ccccagcauc      540

cuggccaucc agaagaaccc gaacuucaag cuggggaccg agguccagga caagaucgug      600

uccgcgaccg gccuccuggc cggcaacgag accgccccgc ccgagguggu caacaacuuc      660

acgcccaucc ugcaggacug caucaagaac aucgaccggu acgcccucga cgaccugaag      720

agcaaggccc uguucaacgu gcucgcggcc ccgaccuacg acaucaccga guaccugcgc      780

gccaccaagg agaagcccga gaacacgccg ugguacggga agaucgacgg cuucaucaac      840

gagcugaaga agcucgcccu guacgggaag aucaacgaca acaacuccug gaucaucgac      900

aacggcaucu accacaucgc cccccugggg aagcuccaca gcaacaacaa gaucggcauc      960

gagacccuga ccgaggugau gaaggucuac ccguaccugu ccaugcagca ccuccagagc     1020

gcggaccaga ucaagcggca cuacgacucc aaggacgccg agggcaacaa gaucccccug     1080

gacaaguuca agaaggaggg gaaggagaag uacugcccca agaccuacac guucgacgac     1140

ggcaagguga ucaucaaggc cggggcccgc guggaggagg agaaggucaa gcggcuguac     1200

ugggccagca aggaggugaa cucccaguuc uuccgcgugu acggcaucga caagccccuc     1260

gaggagggca acccggacga cauccugacc auggucaucu acaacagccc cgaggaguac     1320

aagcugaacu ccgugcucua cggguacgac accaacaacg gcgggaugua caucgagccc     1380

gagggcaccu ucuucacgua cgagcgggag gcgcaggaga gcaccuacac ccuggaggag     1440

cuguuccgcc acgaguacac ccacuaccuc caggggcggu acgccgugcc cggccagugg     1500

ggccgcacga agcuguacga caacgaccgg cugaccuggu acgaggaggg cggcgccgag     1560

cucuucgccg ggagcacccg caccuccggg auccugccgc ggaagagcau cgucuccaac     1620

auccacaaca cgacccgcaa caaccgcuac aagcugagcg acaccgugca cuccaaguac     1680

ggggccagcu ucgaguucua caacuacgcg ugcauguuca uggacuacau guacaacaag     1740

gacaugggca uccucaacaa gcugaacgac cuggccaaga acaacgacgu cgacggcuac     1800

gacaacuaca uccgggaccu guccagcaac uacgcccuca acgacaagua ccaggaccac     1860

augcaggagc gcaucgacaa cuacgagaac cugaccgugc ccuucguggc cgacgacuac     1920

cugguccggc acgcguacaa gaaccccaac gagaucuacu ccgagaucag cgagguggcc     1980

aagcucaagg acgccaaguc cgaggugaag aagagccagu acuucuccac guucacccug     2040

cgcgggagcu acaccggcgg ggccuccaag ggcaagcugg aggaccagaa ggccaugaac     2100

aaguucaucg acgacagccu caagaagcug gacaccuacu ccuggagcgg guacaagacc     2160

cugacggcgu acuucaccaa cuacaagguc gacuccagca accgggugac cuacgacgug     2220

gucuuccacg gcuaccuccc caacgagggc gacagcaaga acucccugcc guacgggaag     2280

aucaacggca ccuacaaggg gacggagaag gagaagauca aguucagcuc cgagggcagc     2340

uucgaccccg acggcaagau cguguccuac gagugggacu ucggggacgg caacaagagc     2400

aacgaggaga accccgagca cuccuacgac aaggugggga ccuacaccgu caagcugaag     2460

gugaccgacg acaagggcga gagcuccgug agcacgacca ccgccgagau caaggaccuc     2520

uccgagaaca agcugcccgu caucuacaug cacgugccga agagcggggc ccugaaccag     2580

aagguggucu ucuacggcaa gggcaccuac gaccccgacg gguccaucgc cggcuaccag     2640

ugggacuucg gggacggcag cgacuucucc agcgagcaga accccuccca cguguacacg     2700

aagaaggggg aguacaccgu gacccuccgc gucauggaca gcagcggcca gauguccgag     2760

aagaccauga agaucaagau cacggacccg guguacccca ucggcaccga gaaggagccc     2820

aacaacagca aggagaccgc cuccgggccc aucgugccgg gcauccccgu cagcgggacc     2880

aucgagaaca cguccgacca ggacuacuuc uacuucgacg ugaucacccc cggcgaggug     2940

aagaucgaca ucaacaagcu gggguacggc ggcgcgaccu gggucgugua cgacgagaac     3000

aacaacgccg ugagcuacgc caccgacgac gggcagaacc uguccggcaa guucaaggcc     3060

gacaagcccg ggcgguacua cauccaccuc uacauguuca acggcagcua caugccguac     3120

cgcaucaaca ucgagggguc cgucggccgg ugaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  1492
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt1)

<400>  1492
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggccgcguuc       60

gccaugcccc ugccgcccca ccccggccac cccggguaca ucaacuucag cuacgaggug      120

cucaccccgc ugaaguggua ccaguccauc cgcccgcccu accccagcua cggcuacgag      180

cccaugggcg gguggcugca ccaccagauc auccccgucc ucucccagca gcacccgccc      240

acgcacaccc ugcagccgca ccaccacauc cccguggugc ccgcccagca gcccgucauc      300

ccccagcagc ccaugaugcc cgugcccggc cagcacagca ugaccccgau ccagcaccac      360

cagcccaacc ugcccccgcc ggcccagcag cccuaccagc cccagcccgu gcagccccag      420

ccccaccagc ccaugcagcc gcagccgccc guccacccca ugcagccgcu cccgccccag      480

cccccgcugc cgcccauguu ccccaugcag ccccugccgc ccaugcuccc cgaccugacc      540

cuggaggccu ggcccuccac ggacaagacc aagcgggagg agguggacug aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  1493
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt1)

<400>  1493
gggagaaagc uuaccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc       60

agcuacgagg ugcucacccc gcugaagugg uaccagucca uccgcccgcc cuaccccagc      120

uacggcuacg agcccauggg cgggugguga ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  1494
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt1)

<400>  1494
gggagaaagc uuaccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc       60

agcuacgagg ugcucacccc gcugaagugg uaccagucca uccgcccgcc gcccaugcuc      120

cccgaccuga cccuggaggc cuggcccucc acggacaaga ccaagcggga ggagguggac      180

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  1495
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt1)

<400>  1495
gggagaaagc uuaccauggc cgugauggcc ccgcggaccc ugguccuccu gcugagcggc       60

gcgcucgccc ugacccagac gugggccaug ccccugccgc cccaccccgg ccaccccggg      120

uacaucaacu ucagcuacga ggugcucacc ccgcugaagu gguaccaguc cauccgcccg      180

cccuacccca gcuacggcua cgagcccaug ggcggguggu gaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  1496
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt1)

<400>  1496
gggagaaagc uuaccauggc cgugauggcc ccgcggaccc ugguccuccu gcugagcggc       60

gcgcucgccc ugacccagac gugggccaug ccccugccgc cccaccccgg ccaccccggg      120

uacaucaacu ucagcuacga ggugcucacc ccgcugaagu gguaccaguc cauccgcccg      180

ccgcccaugc uccccgaccu gacccuggag gccuggcccu ccacggacaa gaccaagcgg      240

gaggaggugg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  1497
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt1)

<400>  1497
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccucguggg ggccgcguuc       60

gccaugcccc ugccgcccca ccccggccac cccggguaca ucaacuucag cuacgagguc      120

cugaccccgc ucaaguggua ccaguccaug auccgcccgc ccuacagcuc cuacggcuac      180

gagcccaugg gcggguggcu gcaccaccag aucauccccg uggugagcca gcagcacccc      240

cugacgcaca cccuccaguc ccaccaccac auccccgucg ugcccgccca gcagccgcgg      300

gugcgccagc aggcccugau gcccgucccc ggccagcaga gcaugacccc cacccagcac      360

caccagccga accugccccu ccccgcccag cagcccuucc agccgcagcc cgugcagccc      420

cagccccacc agccgaugca gccccagccg cccgugcagc ccaugcagcc ccugcugccc      480

cagccgcccc ucccgcccau guucccccug cggccccugc cgcccauccu ccccgaccug      540

caccuggagg cguggcccgc cacggacaag accaagcagg aggaggucga cugaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  1498
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt1)

<400>  1498
gggagaaagc uuaccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc       60

agcuacgagg uccugacccc gcucaagugg uaccagucca ugauccgccc gcccuacagc      120

uccuacggcu acgagcccau gggcgggugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1499
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt1)

<400>  1499
gggagaaagc uuaccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc       60

agcuacgagg uccugacccc gcucaagugg uaccagucca ugauccgccc gccgcccauc      120

cuccccgacc ugcaccugga ggcguggccc gccacggaca agaccaagca ggaggagguc      180

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1500
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt1)

<400>  1500
gggagaaagc uuaccauggc cgugauggcc ccgcggaccc ugguccuccu gcugagcggc       60

gcgcucgccc ugacccagac gugggccaug ccccugccgc cccaccccgg ccaccccggg      120

uacaucaacu ucagcuacga gguccugacc ccgcucaagu gguaccaguc caugauccgc      180

ccgcccuaca gcuccuacgg cuacgagccc augggcgggu ggugaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1501
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt1)

<400>  1501
gggagaaagc uuaccauggc cgugauggcc ccgcggaccc ugguccuccu gcugagcggc       60

gcgcucgccc ugacccagac gugggccaug ccccugccgc cccaccccgg ccaccccggg      120

uacaucaacu ucagcuacga gguccugacc ccgcucaagu gguaccaguc caugauccgc      180

ccgccgccca uccuccccga ccugcaccug gaggcguggc ccgccacgga caagaccaag      240

caggaggagg ucgacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1502
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt1)

<400>  1502
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggccgcguuc       60

agcaugcccc ugccgcccca ccccggccac cccggguaca ucaacuucuc cuacgaggug      120

cucaccccgc ugaaguggua ccagaacaug auccgccacc ccuacacgag cuacggcuac      180

gagcccaugg gcggguggcu gcaccaccag aucauccccg ucguguccca gcagaccccg      240

cagagccacg cccuccagcc ccaccaccac auccccaugg ugcccgccca gcagccgggc      300

aucccccagc agcccaugau gccccugccg gggcagcacu ccaugacccc cacccagcac      360

caccagccca accugccccu cccggcccag cagcccuucc agccccagcc cguccagccg      420

cagccccacc agccccugca gccccagagc ccgaugcacc ccauccagcc ccugcucccg      480

cagccgcccc ugcccccgau guucuccaug cagagccugc uccccgaccu gccccuggag      540

gccuggcccg cgacggacaa gaccaagcgg gaggaggugg acugaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1503
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt1)

<400>  1503
gggagaaagc uuaccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc       60

uccuacgagg ugcucacccc gcugaagugg uaccagaaca ugauccgcca ccccuacacg      120

agcuacggcu acgagcccau gggcgggugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1504
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt1)

<400>  1504
gggagaaagc uuaccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc       60

uccuacgagg ugcucacccc gcugaagugg uaccagaaca ugauccgcca ccccagccug      120

cuccccgacc ugccccugga ggccuggccc gcgacggaca agaccaagcg ggaggaggug      180

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1505
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt1)

<400>  1505
gggagaaagc uuaccauggc cgugauggcc ccgcggaccc ugguccuccu gcugagcggc       60

gcgcucgccc ugacccagac gugggccaug ccccugccgc cccaccccgg ccaccccggg      120

uacaucaacu ucuccuacga ggugcucacc ccgcugaagu gguaccagaa caugauccgc      180

caccccuaca cgagcuacgg cuacgagccc augggcgggu ggugaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1506
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt1)

<400>  1506
gggagaaagc uuaccauggc cgugauggcc ccgcggaccc ugguccuccu gcugagcggc       60

gcgcucgccc ugacccagac gugggccaug ccccugccgc cccaccccgg ccaccccggg      120

uacaucaacu ucuccuacga ggugcucacc ccgcugaagu gguaccagaa caugauccgc      180

caccccagcc ugcuccccga ccugccccug gaggccuggc ccgcgacgga caagaccaag      240

cgggaggagg uggacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1507
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt1)

<400>  1507
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggccgcguuc       60

agcaugcccc ugccgcccca ccccggccac cccggguaca ucaacuucuc cuacauccgc      120

cacccguaca ccagcuacgg cuacgagccc augggcgggu ggcuccacca ccagaucauc      180

cccguggucu cccagcagac gccccagagc cacgcccugc agccgcacca ccacaucccc      240

auggugcccg cccagcagcc cggcaucccg cagcagccca ugaugccccu gcccgggcag      300

cacuccauga ccccgaccca gcaccaccag cccaaccucc cccugcccgc ccagcagccg      360

uuccagcccc agcccgugca gccccagccg caccagcccc ugcagcccca gagccccaug      420

cacccgaucc agccccuccu gccccagccg ccccugccgc ccauguucuc caugcagagc      480

cuccugcccg accugccccu cgaggccugg cccgcgaccg acaagacgaa gcgggaggag      540

gucgacugag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  1508
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt1)

<400>  1508
gggagaaagc uuaccauggg caccuggauc uucuucgccu gccugcucgg ggccagccug       60

gcgaugcccc ugccgcccca ccccggccac cccggguaca ucaacuucuc cuacgaggug      120

cucacgcccc ugaaguggua ccagaacaug auccgccacc ccuacaccag cuacggcuac      180

gagcccaugg gcggguggcu gcaccaccag aucauccccg ucguguccca gcagaccccg      240

cagagccacg cccuccagcc ccaccaccac auccccaugg ugcccgccca gcagccgggc      300

aucccccagc agcccaugau gccccugccg gggcagcacu ccaugacccc cacccagcac      360

caccagccca accugccccu cccggcccag cagcccuucc agccccagcc cguccagccg      420

cagccccacc agccccugca gccccagagc ccgaugcacc ccauccagcc ccugcucccg      480

cagccgcccc ugccgcccau guucuccaug cagagccugc uccccgaccu gccccuggag      540

gccuggcccg cgacggacaa gaccaagcgg gaggaggugg acugaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1509
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt1)

<400>  1509
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggccgcguuc       60

agcaugcccc ugccgcccca ccccggccac cccggguaca ucaacuucuc cuacgaggug      120

cucaccccgc ugaaguggua ccagaacaug auccgccacc ccagccugcu ccccgaccug      180

ccccuggagg ccuggccggc cacggacaag accaagcggg aggaggucga cugaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  1510
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt1)

<400>  1510
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggccgcguuc       60

agcaugcccc ugccgcccca ccccggccac cccggguaca ucaacuucuc cuacgaggac      120

cucuaccugg aggccauccg caucgaccgg accgccuucg ugcugacgcc ccucaagugg      180

uaccagaaca ugauccgcca ccccuacacc agcuacggcu acgagcccau gggcgggugg      240

cugcaccacc agaucauccc cgucgugucc cagcagaccc cgcagagcca cgcccugcag      300

ccccaccacc acauccccau ggugcccgcc cagcagccgg gcauccccca gcagcccaug      360

augccccucc cggggcagca cuccaugacc cccacgcagc accaccagcc caaccugccc      420

cugccggcgc agcagcccuu ccagccccag cccguccagc cgcagcccca ccagccccuc      480

cagccccaga gcccgaugca ccccauccag ccccugcugc cgcagccgcc ccugccgccc      540

auguucucca ugcagagccu ccugcccgac cucccccugg aggccuggcc cgccaccgac      600

aagaccaagc gggaggaggu ggacugagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  1511
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt1)

<400>  1511
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggccgcguuc       60

agcaugcccc ugccgcccca ccccggccac cccggguaca ucaacuucuc cuacgaggug      120

cucaccccgc ugaaguggua ccagaacaug auccgccacc ccacgcccca gagccacgcc      180

cugcagcccc accaccacau cccgaugguc cccgcccagc agcccggcau cccccagcag      240

ccgaugaugc cccuccccgg gcagcacucc augaccccca cccagcacca ccagccgaac      300

cugccccugc ccgcccagca gcccuuccag ccgcagcccg ugcagcccca gccccaccag      360

ccgcuccagc cccagagccc caugcacccc auccagccgc ugcugcccca gcccccgcuc      420

ccgcccaugu ucuccaugca gagccugcug cccgaccucc cccuggaggc cuggcccgcg      480

accgacaaga cgaagcggga ggagguggac ugaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  1512
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt1)

<400>  1512
gggagaaagc uuaccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc       60

agcuacgagg ugcucacccc gcugaagugg uaccagaaca ugauccgcca ccccuacacc      120

uccuacggcu acgagcccau gggcgggugg cugcaccacc agaucauccc cgucgugagc      180

cagcagacgc cgcaguccca cgcccuccag ccccaccacc acauccccau ggugcccgcc      240

cagcagcccg ggauccccca gcagcccaug augccccugc cgggccagca cagcaugacc      300

cccacccagc accaccagcc caaccugccc cucccggcgc agcagcccuu ccagccccag      360

cccguccagc cgcagcccca ccagccccug cagccccagu ccccgaugca ccccauccag      420

ccccugcucc cgcagccgcc ccugccgccc auguucagca ugcagucccu gcuccccgac      480

cugccccugg aggccuggcc cgccaccgac aagacgaagc gggaggaggu ggacugagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  1513
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt1)

<400>  1513
gggagaaagc uuaccaugcc cggcguggcc cgccugccgc uccugcuggg gcuccugcug       60

cucccccggc ccggccgccc ccuggaccug gccgacuaca ccuacgaccu cgccgaggag      120

gacgacagcg agccgcugaa cuacaaggac cccugcaagg ccgccgccuu ccugggggac      180

aucgcccucg acgaggagga ccugcgggcg uuccaggucc agcaggccgu ggaccugcgc      240

cggcacaccg cccgcaaguc cagcaucaag gccgcggugc ccggcaacac guccaccccc      300

agcugccagu ccaccaacgg gcagccgcag cggggcgccu gcggccgcug gcgggggcgc      360

agccgguccc gccgggccgc caccagccgc cccgagcggg ucuggcccga cggcgugauc      420

cccuucguga ucgggggcaa cuucacgggg ucccagcgcg ccgucuuccg gcaggcgaug      480

cgccacuggg agaagcacac gugcgugacc uuccucgagc ggaccgacga ggacagcuac      540

aucguguuca ccuaccgccc gugcggcugc ugcuccuacg ucggccggcg cgggggcggg      600

ccccaggcca ucagcaucgg caagaacugc gacaaguucg gcaucguggu gcacgagcug      660

gggcacgucg ugggcuucug gcacgagcac acccgccccg accgggaccg ccacgugucc      720

aucguccggg agaacaucca gcccgggcag gaguacaacu uccugaagau ggagccgcag      780

gagguggaga gccucggcga gaccuacgac uucgacucca ucaugcacua cgcccgcaac      840

accuucagcc gggggaucuu ccuggacacg aucgugccca aguacgaggu caacggcgug      900

aagccgccca ucggccagcg cacccggcug uccaaggggg acaucgccca ggcccgcaag      960

cucuacaagu gccccgcgug cggcgagacc cugcaggaca gcaccgggaa cuucuccagc     1020

cccgaguacc ccaacggcua cagcgcccac augcacugcg uguggcggau cuccgucacg     1080

cccggggaga agaucauccu gaacuucacc agccucgacc uguaccgcuc ccggcugugc     1140

ugguacgacu acguggaggu gcgcgacggc uucuggcgga aggccccgcu ccgcggccgg     1200

uucugcggga gcaagcugcc cgagcccauc gucuccaccg acagccgccu guggguggag     1260

uuccggucca gcuccaacug ggucggcaag ggguucuucg ccguguacga ggccaucugc     1320

ggcggggacg ugaagaagga cuacggccac auccagagcc ccaacuaccc ggacgacuac     1380

cgccccucca aggucugcau cuggcggauc caggugagcg agggcuucca cguggggcuc     1440

accuuccagu ccuucgagau cgagcgccac gacagcugcg cguacgacua ccuggagguc     1500

cgcgacggcc acuccgagag cuccacgcug aucgggcggu acugcggcua cgagaagccc     1560

gacgacauca agagcaccuc cagccgccuc uggcugaagu ucgugagcga cggcuccauc     1620

aacaaggccg gguucgccgu gaacuucuuc aaggaggucg acgagugcag ccggccgaac     1680

cgcggcgggu gcgagcagcg gugccugaac acccucggcu ccuacaagug cagcugcgac     1740

cccggguacg agcuggcccc cgacaagcgc cggugcgagg ccgcgugcgg cggcuuccug     1800

accaagcuca acggguccau cacgagcccc ggcuggccga aggaguaccc gcccaacaag     1860

aacugcaucu ggcagcuggu ggcccccacc caguaccgca ucucccugca guucgacuuc     1920

uucgagaccg aggggaacga cgugugcaag uacgacuucg ucgaggugcg gagcggccuc     1980

accgccgacu ccaagcugca cgggaaguuc ugcggcagcg agaagcccga ggugaucacg     2040

ucccaguaca acaacaugcg cgucgaguuc aagagcgaca acaccguguc caagaagggc     2100

uucaaggccc acuucuucag cgacaaggac gagugcucca aggacaacgg gggcugccag     2160

caggacugcg ugaacaccuu cgggagcuac gagugccagu gccgguccgg cuucguccug     2220

cacgacaaca agcacgacug caaggaggcg gggugcgacc acaaggugac cagcacgagc     2280

ggcaccauca ccucccccaa cuggcccgac aaguacccca gcaagaagga gugcaccugg     2340

gccaucucca gcacgccggg ccaccgcgug aagcucaccu ucauggagau ggacaucgag     2400

ucccagcccg agugcgccua cgaccaccug gaggucuucg acgggcggga cgccaaggcc     2460

cccgugcugg gccgcuucug cgggagcaag aagcccgagc cggugcucgc gaccggcucc     2520

cggauguucc ugcgcuucua cagcgacaac uccguccagc ggaagggguu ccaggccagc     2580

cacgccaccg agugcggcgg ccaggugcgc gccgacguga agaccaagga ccuguacucc     2640

cacgcccagu ucggggacaa caacuacccc ggcggggucg acugcgagug ggugaucgug     2700

gcggaggagg gcuacggcgu cgagcuggug uuccagacgu ucgaggugga ggaggagacc     2760

gacugcgggu acgacuacau ggagcuguuc gacggcuacg acagcaccgc gccccggcuc     2820

gggcgcuacu gcggcuccgg gcccccggag gaggucuaca gcgccggcga cuccgugcug     2880

gugaaguucc acagcgacga caccaucacg aagaagggcu uccaccuccg guacaccucc     2940

accaaguucc aggacacccu gcacagccgc aagugaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  1514
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt1)

<400>  1514
gggagaaagc uuaccauggu ggccggcacc cgcugccugc ucgcccugcu gcucccccag       60

guccugcucg ggggcgcggc cgggcuggug ccggagcugg gccggcgcaa guucgccgcc      120

gccagcuccg ggcggcccag cucccagccc agcgacgagg ugcuguccga guucgagcuc      180

cgccugcuga gcauguucgg ccucaagcag cggcccaccc cgucccgcga cgcggucgug      240

ccgcccuaca ugcuggaccu guaccggcgc cacagcggcc agcccggguc ccccgccccc      300

gaccaccggc ucgagcgcgc cgccagccgg gcgaacacgg ugcgcuccuu ccaccacgag      360

gagagccugg aggagcugcc cgagaccucc ggcaagacca cccggcgcuu cuucuucaac      420

cucagcucca uccccacgga ggaguucauc accagcgccg agcugcaggu cuuccgggag      480

cagaugcagg acgcccuggg gaacaacucc agcuuccacc accgcaucaa caucuacgag      540

aucaucaagc cggccaccgc caacuccaag uuccccguga cccggcuccu ggacacgcgc      600

cuggugaacc agaacgcgag ccggugggag agcuucgacg ucacccccgc cgugaugcgc      660

uggaccgccc agggccacgc caaccacggg uucguggucg agguggccca ccucgaggag      720

aagcagggcg uguccaagcg gcacguccgc aucagccgcu cccugcacca ggacgagcac      780

agcugguccc agauccggcc ccugcucgug accuucggcc acgacgggaa gggccacccg      840

cugcacaagc gcgagaagcg gcaggcgaag cacaagcagc gcaagcggcu caagagcucc      900

ugcaagcgcc acccccugua cguggacuuc agcgacgucg gguggaacga cuggaucgug      960

gccccgcccg gcuaccacgc cuucuacugc cacggcgagu gccccuuccc ccuggccgac     1020

caccugaacu ccacgaacca cgccaucgug cagacccucg ucaacagcgu gaacuccaag     1080

auccccaagg cgugcugcgu gcccaccgag cugagcgcca ucuccaugcu guaccucgac     1140

gagaacgaga aggucgugcu gaagaacuac caggacaugg ucguggaggg gugcggcugc     1200

cggugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  1515
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt1)

<400>  1515
gggagaaagc uuaccaugau ccccggcaac cgcaugcuga uggugguccu ccugugccag       60

gugcugcucg ggggcgccag ccacgccucc cugaucccgg agaccgggaa gaagaaggug      120

gcggagaucc agggccacgc cgggggccgg cgcagcggcc agucccacga gcugcuccgg      180

gacuucgagg ccacccugcu gcagauguuc gggcuccgcc ggcgccccca gcccagcaag      240

uccgccguca uccccgacua caugcgggac cuguaccgcc ugcagagcgg cgaggaggag      300

gaggagcaga uccacuccac ggggcucgag uacccggagc ggcccgccag ccgcgcgaac      360

accgugcggu ccuuccacca cgaggagcac cuggagaaca uccccggcac cagcgagaac      420

uccgccuucc gcuuccuguu caaccucagc uccauccccg agaacgaggu gaucagcucc      480

gccgagcugc ggcuguuccg cgagcagguc gaccaggggc cggacuggga gcggggcuuc      540

caccgcauca acaucuacga ggugaugaag ccgcccgccg aggugguccc cggccaccuc      600

aucacccggc ugcuggacac gcgccucgug caccacaacg ugacccggug ggagaccuuc      660

gacgucagcc ccgcggugcu gcgcuggacc cgggagaagc agcccaacua cgggcuggcc      720

aucgagguga cgcaccucca ccagacccgc acccaccagg gccagcacgu ccgcaucucc      780

cggagccugc cccagggguc cggcaacugg gcccagcugc gcccccuccu ggugaccuuc      840

ggccacgacg ggcggggcca cgcccugacg cgccggcgcc gggccaagcg cagcccgaag      900

caccacagcc agcgggcgcg caagaagaac aagaacugcc ggcgccacuc ccucuacgug      960

gacuucagcg acgucgggug gaacgacugg aucguggccc cgcccggcua ccaggccuuc     1020

uacugccacg gggacugccc cuucccccug gccgaccacc ugaacuccac caaccacgcc     1080

aucgugcaga cccucgucaa cagcgugaac uccagcaucc ccaaggcgug cugcgugccc     1140

accgagcugu ccgccaucag caugcuguac cucgacgagu acgacaaggu cgugcugaag     1200

aacuaccagg agauggucgu ggagggcugc ggcugccggu gaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  1516
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt1)

<400>  1516
gggagaaagc uuaccaugcc cggccugggg cgccgggccc aguggcucug cugguggugg       60

ggccugcugu gcagcugcug cgggccgccg ccccuccggc cgccccugcc cgccgcggcc      120

gccgccgccg cgggcgggca gcugcucggc gacggcgggu cccccggccg gaccgagcag      180

cccccgccca gcccccaguc cagcuccggg uuccuguacc gccggcugaa gacccaggag      240

aagcgcgaga ugcagaagga gauccucagc gugcugggcc ugccccaccg gccccgcccc      300

cuccacgggc ugcagcagcc ccagcccccg gcccugcggc agcaggagga gcagcagcag      360

cagcagcagc ucccccgcgg cgagcccccg cccggccggc ugaaguccgc gccccuguuc      420

augcucgacc uguacaacgc ccugagcgcc gacaacgacg aggacggggc cuccgagggc      480

gagcgccagc agagcuggcc ccacgaggcc gccuccagcu cccagcggcg ccagcccccg      540

cccggggccg cgcacccccu caaccgcaag agccugcugg cccccggcuc cggcagcggg      600

ggcgccuccc cgcucacgag cgcccaggac uccgccuucc ugaacgacgc ggacaugguc      660

augagcuucg ugaaccuggu ggaguacgac aaggaguuca gcccccgcca gcggcaccac      720

aaggaguuca aguucaaccu cucccagauc cccgaggggg aggucgugac cgccgccgag      780

uuccgcaucu acaaggacug cgugaugggc agcuucaaga accagaccuu ccugaucucc      840

aucuaccagg uccugcagga gcaccagcac cgggacagcg accucuuccu gcuggacacc      900

cgcguggugu gggccuccga ggaggggugg cucgaguucg acaucacggc caccagcaac      960

cugugggucg ugaccccgca gcacaacaug ggccugcagc ucuccguggu cacccgggac     1020

ggcgugcacg ugcacccccg cgcggccggg cuggucggcc gcgacgggcc cuacgacaag     1080

cagcccuuca ugguggccuu cuucaaggug agcgaggucc acgugcggac gacccgcucc     1140

gccagcuccc ggcgccggca gcagagccgc aaccggucca cccagagcca ggacguggcc     1200

cgcgucucca gcgcguccga cuacaacagc uccgagcuga agaccgccug ccggaagcac     1260

gagcucuacg ugagcuucca ggaccugggc uggcaggacu ggaucaucgc cccgaagggg     1320

uacgccgcga acuacugcga cggcgagugc agcuuccccc ugaacgccca caugaacgcc     1380

acgaaccacg ccaucgugca gacccucguc caccugauga accccgagua cgugcccaag     1440

ccgugcugcg cccccaccaa gcugaacgcg aucuccgucc ucuacuucga cgacaacagc     1500

aacgugaucc ugaagaagua ccgcaacaug gugguccggg ccugcggcug ccacugagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  1517
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt1)

<400>  1517
gggagaaagc uuaccaugca cgugcgcagc cugcgggccg ccgcgcccca cuccuucguc       60

gcccucuggg ccccgcuguu ccugcuccgc agcgcccugg ccgacuucuc ccuggacaac      120

gaggugcaca gcuccuucau ccaccggcgc cuccggagcc aggagcgccg ggagaugcag      180

cgcgagaucc uguccauccu gggccucccc caccggcccc gcccccaccu ccaggggaag      240

cacaacagcg cgccgauguu caugcuggac cuguacaacg ccauggccgu ggaggagggc      300

gggggccccg ggggccaggg cuucuccuac cccuacaagg ccgucuucag cacccagggg      360

cccccgcugg cgucccugca ggacagccac uuccucaccg acgccgacau ggugaugucc      420

uucgugaacc uggucgagca cgacaaggag uucuuccacc cccgguacca ccaccgcgag      480

uuccgguucg accugagcaa gauccccgag ggcgaggccg ugacggccgc cgaguuccgc      540

aucuacaagg acuacauccg ggagcgcuuc gacaacgaga ccuuccggau cuccguguac      600

cagguccucc aggagcaccu ggggcgcgag agcgaccugu uccuccugga cucccggacc      660

cugugggcga gcgaggaggg cuggcucgug uucgacauca ccgccacguc caaccacugg      720

guggucaacc cccgccacaa ccuggggcug cagcucagcg uggagacccu ggacggccag      780

agcaucaacc cgaagcuggc cggccucauc gggcggcacg gcccccagaa caagcagccc      840

uucauggugg ccuucuucaa ggccaccgag guccacuucc gcuccauccg cagcaccggg      900

uccaagcagc ggagccagaa ccgcuccaag acgcccaaga accaggaggc gcugcggaug      960

gccaacgugg ccgagaacag cuccagcgac cagcgccagg ccugcaagaa gcacgagcug     1020

uacguguccu uccgggaccu cggcuggcag gacuggauca ucgccccgga gggcuacgcg     1080

gccuacuacu gcgaggggga gugcgccuuc ccccugaaca gcuacaugaa cgccaccaac     1140

cacgccaucg uccagacccu ggugcacuuc aucaaccccg agaccgugcc caagccgugc     1200

ugcgcgccca cgcagcucaa cgccaucucc guccuguacu ucgacgacag cuccaacgug     1260

auccugaaga aguaccgcaa cauggugguc cgggccugcg gcugccacug aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  1518
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt1)

<400>  1518
gggagaaagc uuaccaugaa ggccagcgcc gcgcugcucu gccugcugcu caccgccgcc       60

gccuucagcc cccagggccu ggcccagccg guggggauca acaccuccac gaccugcugc      120

uaccgcuuca ucaacaagaa gauccccaag cagcggcugg aguccuaccg ccggaccacc      180

agcucccacu gcccccgcga ggcggucauc uucaagacga agcucgacaa ggagaucugc      240

gccgacccca cccagaagug ggugcaggac uucaugaagc accuggacaa gaagacccag      300

accccgaagc ugugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  1519
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt1)

<400>  1519
gggagaaagc uuaccaugcu gcucacccug aucauccugc uccccguggu cagcaaguuc       60

uccuucguga gccuguccgc gccccagcac uggagcugcc ccgagggcac ccuggccggg      120

aacggcaacu ccacgugcgu ggggcccgcc cccuuccuca ucuucagcca cggcaacucc      180

aucuuccgca ucgacaccga ggggaccaac uacgagcagc uggucgugga cgccggcgug      240

agcgucauca uggacuucca cuacaacgag aagcggaucu acugggugga ccuggagcgc      300

cagcuccugc agcggguguu ccugaacggc ucccgccagg agcgggucug caacaucgag      360

aagaacguga gcgggauggc caucaacugg aucaacgagg aggugaucug guccaaccag      420

caggagggca ucaucaccgu cacggacaug aaggggaaca acagccacau ccuccugucc      480

gcccugaagu acccggccaa cguggcggug gaccccgucg agcgcuucau cuucuggagc      540

uccgaggugg ccggcagccu cuaccgggcc gaccuggacg gggugggcgu caaggcccug      600

cucgagaccu ccgagaagau caccgcggug agccuggacg ugcuggacaa gcgccucuuc      660

uggauccagu acaaccggga gggcuccaac agccugaucu gcagcugcga cuacgacggg      720

ggcuccgucc acaucagcaa gcaccccacc cagcacaacc uguucgccau gucccucuuc      780

ggggaccgca ucuucuacag cacguggaag augaagacca ucuggaucgc caacaagcac      840

accggcaagg acauggugcg gaucaaccug cacuccagcu ucgugccccu gggcgagcuc      900

aaggucgugc acccgcuggc ccagcccaag gccgaggacg acaccuggga gcccgagcag      960

aagcugugca agcuccgcaa ggggaacugc uccagcacgg ucugcggcca ggaccugcag     1020

ucccaccugu gcaugugcgc ggagggguac gcccucagcc gggaccgcaa guacugcgag     1080

gacgugaacg agugcgccuu cuggaaccac ggcugcaccc uggggugcaa gaacaccccc     1140

ggcuccuacu acugcacgug cccggugggc uucguccugc uccccgacgg gaagcggugc     1200

caccagcugg ugagcugccc ccgcaacgug uccgagugca gccacgacug cguccugacc     1260

uccgagggcc cccucugcuu cugcccggag gggagcgugc uggagcggga cggcaagacc     1320

ugcuccgggu gcagcucccc cgacaacggc ggcugcagcc agcugugcgu gccccucagc     1380

cccgucuccu gggagugcga cugcuucccg ggguacgacc ugcagcugga cgagaagucc     1440

ugcgccgcca gcggccccca gcccuuccuc cuguucgcga acagccagga cauccgccac     1500

augcacuucg acgggaccga cuacggcacc cugcucuccc agcagauggg gaugguguac     1560

gcccuggacc acgaccccgu ggagaacaag aucuacuucg cccacacggc ccugaagugg     1620

aucgagcggg ccaacaugga cggcagccag cgcgagcggc ugaucgagga gggcgucgac     1680

gugccggagg ggcucgcggu ggacuggauc ggccgccgcu ucuacuggac cgaccggggg     1740

aagucccuga ucggccgcag cgaccugaac ggcaagcggu ccaagaucau caccaaggag     1800

aacaucagcc agccccgcgg gaucgccguc caccccaugg ccaagcgccu cuucuggacc     1860

gacacgggca ucaacccccg gaucgagucc agcucccugc aggggcuggg ccggcucgug     1920

aucgccagcu ccgaccugau cuggccgagc gggaucacca ucgacuuccu gaccgacaag     1980

cucuacuggu gcgacgccaa gcaguccgug aucgagaugg cgaaccugga cggcagcaag     2040

cgccggcgcc ugacccagaa cgacgucggc caccccuucg ccguggccgu guucgaggac     2100

uacgucuggu ucagcgacug ggccaugccc uccgugaugc gggugaacaa gcgcacgggg     2160

aaggaccggg uccgccucca gggcagcaug cugaagccgu ccagccuggu ggugguccac     2220

ccccucgcga agcccggggc cgaccccugc cuguaccaga acggcgggug cgagcacauc     2280

ugcaagaagc ggcugggcac cgccuggugc uccugccgcg agggcuucau gaaggccagc     2340

gacgggaaga ccugccucgc ccuggacggc caccagcugc ucgccggggg cgagguggac     2400

cugaagaacc aggugacccc gcuggacauc cucuccaaga cgcgggucag cgaggacaac     2460

aucaccgagu cccagcacau gcugguggcc gagaucaugg ugagcgacca ggacgacugc     2520

gcccccgucg ggugcuccau guacgcccgc ugcaucagcg agggcgagga cgcgaccugc     2580

cagugccuga agggcuucgc gggggacggc aagcucugcu ccgacaucga cgagugcgag     2640

augggggugc ccgugugccc gccggccagc uccaagugca ucaacaccga gggcggguac     2700

gucugccggu gcagcgaggg cuaccagggc gacgggaucc acugccugga caucgacgag     2760

ugccagcugg gcgagcacuc cugcggggag aacgccagcu gcacgaacac cgagggcggc     2820

uacacgugca ugugcgccgg gcgccucucc gagcccggcc ugaucugccc cgacagcacg     2880

cccccgcccc accuccgcga ggacgaccac cacuacagcg ugcggaacuc cgacagcgag     2940

ugcccccugu cccacgacgg guacugccug cacgacggcg ugugcaugua caucgaggcc     3000

cuggacaagu acgcgugcaa cugcgucgug ggguacaucg gcgagcgcug ccaguaccgg     3060

gaccucaagu ggugggagcu gcgccacgcc ggccacgggc agcagcagaa ggugaucguc     3120

guggccgugu gcgucguggu gcuggucaug cuccugcugc ucagccugug gggcgcccac     3180

uacuaccgga cccagaagcu gcucuccaag aaccccaaga acccguacga ggagagcucc     3240

cgcgacgugc ggagccgccg gcccgcggac accgaggacg ggauguccag cugcccccag     3300

cccugguucg uggucaucaa ggagcaccag gaccugaaga acggcgggca gccgguggcc     3360

ggcgaggacg gccaggccgc cgacgggucc augcagccca ccagcuggcg ccaggagccc     3420

cagcugugcg gcauggggac cgagcagggc ugcuggaucc ccgucuccag cgacaagggg     3480

uccugccccc aggugaugga gcggagcuuc cacaugcccu ccuacggcac ccagacccuc     3540

gagggcgggg uggagaagcc ccacagccug cuguccgcca acccgcucug gcagcagcgc     3600

gcgcuggacc cgccccacca gauggagcug acccagugag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  1520
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt1)

<400>  1520
gggagaaagc uuaccaugac cgccggccgc cggauggaga ugcugugcgc cgggcgcgug       60

cccgcgcucc ugcugugccu cggcuuccac cuccugcagg ccguccugag caccacggug      120

aucccguccu gcauccccgg ggagagcucc gacaacugca ccgcccuggu gcagaccgag      180

gacaaccccc gggucgccca ggugagcauc accaagugcu ccagcgacau gaacggcuac      240

ugccugcacg ggcagugcau cuaccucgug gacauguccc agaacuacug ccgcugcgag      300

gucggcuaca cgggcgugcg gugcgagcac uucuuccuga ccgugcacca gccccugagc      360

aaggaguacg ucgcccucac cgugauccug aucauccugu uccucaucac cguggucggg      420

uccacguacu acuucugccg cugguaccgg aaccgcaaga gcaaggagcc gaagaaggag      480

uacgagcggg ugaccuccgg cgaccccgag cugccccagg ugugaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  1521
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt1)

<400>  1521
gggagaaagc uuaccauggc cgagggcgag aucaccaccu ucacggcccu gaccgagaag       60

uucaaccugc ccccggggaa cuacaagaag cccaagcucc uguacugcag caacggcggg      120

cacuuccucc gcauccugcc cgacggcacc guggacggga cccgggaccg cuccgaccag      180

cacauccagc ugcagcucag cgcggagucc gucggcgagg uguacaucaa gagcacggag      240

accggccagu accuggccau ggacaccgac gggcugcucu acggcuccca gacccccaac      300

gaggagugcc uguuccugga gcggcucgag gagaaccacu acaacacgua caucagcaag      360

aagcacgccg agaagaacug guucgugggg cugaagaaga acggcuccug caagcgcggg      420

ccgcggaccc acuacggcca gaaggccauc cuguuccucc cccugcccgu cagcuccgac      480

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  1522
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt1)

<400>  1522
gggagaaagc uuaccauggu gggcgucggg ggcggggacg uggaggacgu gaccccgcgc       60

ccgggcgggu gccagaucag cggccggggc gcccgcgggu gcaacggcau ccccggggcc      120

gcggccuggg aggccgcccu gccccggcgc cggccccgcc ggcacccguc cgucaacccc      180

cgcagccggg ccgcgggcag cccccgcacc cgggggcgcc ggacggagga gcgccccucc      240

ggcucccggc ucggcgaccg cgggcggggc cgcgcccugc ccgggggccg gcugggcggg      300

cgcggccggg ggcgcgcccc cgagcgcgug ggcgggcggg gccgcggccg ggggaccgcc      360

gcgccccgcg ccgcccccgc cgcccggggc agccgcccgg ggcccgcggg caccauggcc      420

gccgggucca ucaccacgcu ccccgcccug cccgaggacg gcggcagcgg ggccuucccg      480

cccggccacu ucaaggaccc caagcggcug uacugcaaga acgggggcuu cuuccuccgc      540

auccaccccg acgggcgggu ggacggcguc cgcgagaagu ccgacccgca caucaagcug      600

cagcugcagg cggaggagcg gggcguggug agcaucaagg gggucugcgc caaccgcuac      660

cucgccauga aggaggacgg ccggcugcug gccuccaagu gcgugaccga cgagugcuuc      720

uucuucgagc gccucgagag caacaacuac aacaccuacc ggucccgcaa guacaccagc      780

ugguacgugg cccugaagcg gacggggcag uacaagcugg gcuccaagac cggccccggg      840

cagaaggcga uccucuuccu gcccaugagc gccaaguccu gaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  1523
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt1)

<400>  1523
gggagaaagc uuaccaugca caaguggauc cugaccugga uccuccccac ccugcuguac       60

cgcagcugcu uccacaucau cugccucgug ggcacgaucu cccuggccug caacgacaug      120

accccggagc agauggccac caacgucaac ugcagcuccc ccgagcggca cacccgcagc      180

uacgacuaca uggagggcgg ggacauccgg gugcgccggc uguucugccg cacgcagugg      240

uaccuccgga ucgacaagcg cgggaaggug aagggcaccc aggagaugaa gaacaacuac      300

aacaucaugg agauccggac cgucgcggug gggaucgugg ccaucaaggg cgucgagucc      360

gaguucuacc uggccaugaa caaggagggc aagcuguacg ccaagaagga gugcaacgag      420

gacugcaacu ucaaggagcu cauccuggag aaccacuaca acaccuacgc cagcgcgaag      480

uggacgcaca acgggggcga gauguucgug gcccugaacc agaaggggau ccccgugcgc      540

ggcaagaaga ccaagaagga gcagaagacc gcccacuucc uccccauggc caucaccuga      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  1524
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt1)

<400>  1524
gggagaaagc uuaccaugaa gcugcucccc agcguggucc ugaagcuguu ccucgccgcc       60

gugcuguccg cgcuggugac cggcgagagc cucgagcggc ugcggcgcgg gcuggccgcc      120

ggcaccucca acccggaccc gcccacgguc agcaccgacc agcuccugcc ccucgggggc      180

gggcgggacc gcaaggugcg ggaccugcag gaggccgacc uggaccugcu ccgcgugacc      240

cuguccagca agccccaggc ccuggcgacc cccaacaagg aggagcacgg caagcggaag      300

aagaagggca aggggcucgg caagaagcgc gaccccugcc ugcggaagua caaggacuuc      360

ugcauccacg gggagugcaa guacgucaag gagcugcgcg cccccuccug caucugccac      420

ccgggcuacc acggggagcg gugccacggc cucagccugc ccguggagaa ccgccuguac      480

acguacgacc acaccaccau ccucgccgug gucgccgugg ugcuguccag cgucugccug      540

cucgugaucg ugggccugcu gauguuccgg uaccaccgcc gcgggggcua cgacgucgag      600

aacgaggaga aggugaagcu cgggaugacc aacucccacu gaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  1525
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt1)

<400>  1525
gggagaaagc uuaccaugug ggugaccaag cugcuccccg cccugcugcu ccagcacguc       60

cugcugcacc uccugcugcu cccgaucgcc auccccuacg cggagggcca gcgcaagcgg      120

cgcaacacca uccacgaguu caagaagucc gccaagacga cccugaucaa gaucgacccc      180

gcccugaaga ucaagaccaa gaaggugaac accgccgacc agugcgccaa ccggugcacg      240

cgcaacaagg ggcuccccuu cacgugcaag gcguucgugu ucgacaaggc ccggaagcag      300

ugccuguggu ucccguucaa cagcaugagc uccggcguca agaaggaguu cgggcacgag      360

uucgaccugu acgagaacaa ggacuacauc cgcaacugca ucaucggcaa ggggcggagc      420

uacaagggca ccguguccau caccaagagc ggcaucaagu gccagcccug guccagcaug      480

aucccccacg agcacuccuu ccuccccagc uccuaccgcg ggaaggaccu gcaggagaac      540

uacugccgga acccgcgcgg cgaggagggc gggcccuggu gcuucaccag caaccccgag      600

gugcgguacg aggucugcga caucccccag ugcuccgagg uggagugcau gaccugcaac      660

ggggagagcu accgcggccu gauggaccac accgaguccg gcaagaucug ccagcggugg      720

gaccaccaga ccccgcaccg ccacaaguuc cuccccgagc gguaccccga caagggguuc      780

gacgacaacu acugccgcaa ccccgacggc cagccgcggc ccuggugcua cacgcuggac      840

ccccacaccc gcugggagua cugcgccauc aagaccugcg ccgacaacac caugaacgac      900

acggacgugc cccuggagac caccgagugc auccaggggc agggcgaggg cuaccggggg      960

accgucaaca cgaucuggaa cggcaucccg ugccagcgcu gggacagcca guacccccac     1020

gagcacgaca ugacccccga gaacuucaag ugcaaggacc uccgggagaa cuacugccgc     1080

aaccccgacg gguccgagag cccguggugc uucaccaccg accccaacau ccgcgugggc     1140

uacugcuccc agauccccaa cugcgacaug agccacgggc aggacugcua ccggggcaac     1200

ggcaagaacu acauggggaa ccugagccag acgcgcuccg gccugaccug cagcaugugg     1260

gacaagaaca uggaggaccu ccaccggcac aucuucuggg agcccgacgc guccaagcug     1320

aacgagaacu acugccgcaa cccggacgac gacgcccacg ggcccuggug cuacaccggc     1380

aacccccuga ucccguggga cuacugcccc aucagccggu gcgaggggga caccacgccc     1440

accaucguga accucgacca ccccgucauc uccugcgcca agaccaagca gcugcgcgug     1500

gugaacggca ucccgacccg gacgaacauc ggcuggaugg ucagccugcg cuaccggaac     1560

aagcacaucu gcgggggcuc ccucaucaag gagagcuggg ugcugaccgc ccgccagugc     1620

uuccccuccc gggaccugaa ggacuacgag gccuggcucg ggauccacga cgugcacggc     1680

cgcggggacg agaagugcaa gcagguccug aacgugagcc agcuggugua cggccccgag     1740

ggcuccgacc ucguccugau gaagcuggcg cggcccgccg ugcucgacga cuucgugagc     1800

accaucgacc ugccgaacua cgggugcacc auccccgaga agacguccug cagcgucuac     1860

ggcugggggu acaccggccu gaucaacuac gacggccucc ugcgcguggc ccaccuguac     1920

aucaugggga acgagaagug cucccagcac caccggggca aggucacccu caacgagagc     1980

gagaucugcg ccggggccga gaagaucggc uccgggcccu gcgagggcga cuacggcggg     2040

ccccuggugu gcgagcagca caagaugcgc auggugcugg gcgucaucgu gccggggcgg     2100

ggcugcgcga uccccaaccg ccccgggauc uucgugcggg ucgccuacua cgccaagugg     2160

auccacaaga ucauccucac cuacaaggug ccccagagcu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  1526
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt1)

<400>  1526
gggagaaagc uuaccauggc caaggccgcg gccaucggca ucgaccuggg gaccaccuac       60

agcugcgugg gcguguucca gcacgggaag guggagauca ucgccaacga ccagggcaac      120

cgcacgaccc ccuccuacgu ggccuucacc gacaccgagc ggcucaucgg ggacgccgcg      180

aagaaccagg ucgcccugaa cccgcagaac acgguguucg acgccaagcg ccugaucggc      240

cggaaguucg gcgaccccgu gguccagagc gacaugaagc acuggcccuu ccaggugauc      300

aacgacgggg acaagcccaa ggugcagguc uccuacaagg gcgagaccaa ggccuucuac      360

ccggaggaga ucagcuccau ggugcucacc aagaugaagg agaucgcgga ggccuaccug      420

ggguaccccg ugaccaacgc cgucaucacg gugcccgccu acuucaacga cagccagcgc      480

caggccacca aggacgcggg cgugaucgcc gggcugaacg uccuccggau caucaacgag      540

cccaccgccg ccgccaucgc guacggccug gaccgcaccg gcaaggggga gcggaacgug      600

cugaucuucg accucggcgg gggcacguuc gacgugucca uccugaccau cgacgacggc      660

aucuucgagg ucaaggccac cgccggggac acccaccugg gcggggagga cuucgacaac      720

cgccucguga accacuucgu ggaggaguuc aagcggaagc acaagaagga caucagccag      780

aacaagcgcg ccguccggcg ccugcggacg gccugcgagc gcgcgaagcg gacccugucc      840

agcuccaccc aggccagccu cgagaucgac ucccuguucg agggcaucga cuucuacacc      900

agcaucacgc gcgcccgguu cgaggagcug ugcuccgacc ucuuccgcag cacccuggag      960

ccgguggaga aggcccugcg ggacgccaag cucgacaagg cgcagaucca cgaccuggug     1020

cuggucgggg gcuccacccg cauccccaag gugcagaagc uccugcagga cuucuucaac     1080

ggccgggacc ugaacaagag caucaacccc gacgaggccg ucgccuacgg ggccgcggug     1140

caggccgcca uccucauggg cgacaagucc gagaacgugc aggaccugcu gcuccuggac     1200

gucgcgcccc ugagccucgg gcuggagacc gccggcgggg ugaugacggc ccugaucaag     1260

cgcaacagca ccaucccgac caagcagacc cagaucuuca cgaccuacuc cgacaaccag     1320

cccggcgugc ucauccaggu cuacgagggc gagcgcgcca ugaccaagga caacaaccug     1380

cuggggcggu ucgagcucag cggcaucccg cccgcgcccc gcggggugcc ccagaucgag     1440

gugaccuucg acaucgacgc caacggcauc cugaacguca cggccaccga caaguccacc     1500

gggaaggcca acaagaucac caucacgaac gacaagggcc ggcugagcaa ggaggagauc     1560

gagcgcaugg ugcaggaggc cgagaaguac aaggccgagg acgaggugca gcgggagcgc     1620

gucuccgcca agaacgcccu cgagagcuac gcguucaaca ugaaguccgc cguggaggac     1680

gagggccuga aggggaagau cagcgaggcc gacaagaaga aggugcugga caagugccag     1740

gaggucaucu ccuggcucga cgccaacacc cuggcggaga aggacgaguu cgagcacaag     1800

cggaaggagc uggagcaggu cugcaacccc aucaucagcg gccucuacca gggggccggc     1860

ggccccgggc cgggcggguu cggcgcccag gggcccaagg gcggcuccgg gagcggcccc     1920

accaucgagg agguggacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1527
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt1)

<400>  1527
gggagaaagc uuaccauggc caaggccgcg gccaucggca ucgaccuggg gaccaccuac       60

agcugcgugg gcguguucca gcacgggaag guggagauca ucgccaacga ccagggcaac      120

cgcacgaccc ccuccuacgu ggccuucacc gacaccgagc ggcucaucgg ggacgccgcg      180

aagaaccagg ucgcccugaa cccgcagaac acgguguucg acgccaagcg ccugaucggc      240

cggaaguucg gcgaccccgu gguccagagc gacaugaagc acuggcccuu ccaggugauc      300

aacgacgggg acaagcccaa ggugcagguc uccuacaagg gcgagaccaa ggccuucuac      360

ccggaggaga ucagcuccau ggugcucacc aagaugaagg agaucgcgga ggccuaccug      420

ggguaccccg ugaccaacgc cgucaucacg gugcccgccu acuucaacga cagccagcgc      480

caggccacca aggacgcggg cgugaucgcc gggcugaacg uccuccggau caucaacgag      540

cccaccgccg ccgccaucgc guacggccug gaccgcaccg gcaaggggga gcggaacgug      600

cugaucuucg accucggcgg gggcacguuc gacgugucca uccugaccau cgacgacggc      660

aucuucgagg ucaaggccac cgccggggac acccaccugg gcggggagga cuucgacaac      720

cgccucguga accacuucgu ggaggaguuc aagcggaagc acaagaagga caucagccag      780

aacaagcgcg ccguccggcg ccugcggacg gccugcgagc gcgcgaagcg gacccugucc      840

agcuccaccc aggccagccu cgagaucgac ucccuguucg agggcaucga cuucuacacc      900

agcaucacgc gcgcccgguu cgaggagcug ugcuccgacc ucuuccgcag cacccuggag      960

ccgguggaga aggcccugcg ggacgccaag cucgacaagg cgcagaucca cgaccuggug     1020

cuggucgggg gcuccacccg cauccccaag gugcagaagc uccugcagga cuucuucaac     1080

ggccgggacc ugaacaagag caucaacccc gacgaggccg ucgccuacgg ggccgcggug     1140

caggccgcca uccucauggg cgacaagucc gagaacgugc aggaccugcu gcuccuggac     1200

gucgcgcccc ugagccucgg gcuggagacc gccggcgggg ugaugacggc ccugaucaag     1260

cgcaacagca ccaucccgac caagcagacc cagaucuuca cgaccuacuc cgacaaccag     1320

cccggcgugc ucauccaggu cuacgagggc gagcgcgcca ugaccaagga caacaaccug     1380

cuggggcggu ucgagcucag cggcaucccg cccgcgcccc gcggggugcc ccagaucgag     1440

gugaccuucg acaucgacgc caacggcauc cugaacguca cggccaccga caaguccacc     1500

gggaaggcca acaagaucac caucacgaac gacaagggcc ggcugagcaa ggaggagauc     1560

gagcgcaugg ugcaggaggc cgagaaguac aaggccgagg acgaggugca gcgggagcgc     1620

gucuccgcca agaacgcccu cgagagcuac gcguucaaca ugaaguccgc cguggaggac     1680

gagggccuga aggggaagau cagcgaggcc gacaagaaga aggugcugga caagugccag     1740

gaggucaucu ccuggcucga cgccaacacc cuggcggaga aggacgaguu cgagcacaag     1800

cggaaggagc uggagcaggu cugcaacccc aucaucagcg gccucuacca gggggccggc     1860

ggccccgggc cgggcggguu cggcgcccag gggcccaagg gcggcuccgg gagcggcccc     1920

accaucgagg agguggacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1528
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt1)

<400>  1528
gggagaaagc uuaccauggc caccgccaag ggcaucgcga ucgggaucga ccugggcacc       60

acguacagcu gcgugggggu cuuccagcac ggcaaggugg agaucaucgc caacgaccag      120

gggaaccgca ccacccccuc cuacguggcc uucaccgaca cggagcggcu caucggcgac      180

gccgccaaga accaggucgc gaugaacccg cagaacaccg uguucgacgc caagcgccug      240

aucggccgga aguucaacga ccccgugguc caggccgaca ugaagcugug gcccuuccag      300

gugaucaacg agggcgggaa gcccaaggug cucgucagcu acaaggggga gaacaaggcc      360

uucuacccgg aggagaucuc cagcauggug cugaccaagc ugaaggagac cgcggaggcc      420

uuccucggcc accccgugac gaacgccguc aucaccgugc ccgccuacuu caacgacucc      480

cagcgccagg ccaccaagga cgcgggggug aucgccggcc ugaacguccu gcggaucauc      540

aacgagccca ccgccgccgc caucgcguac ggccucgaca agggcgggca gggggagcgc      600

cacgugcuga ucuucgaccu gggcggcggg acguucgacg ugagcauccu caccaucgac      660

gacggcaucu ucgaggucaa ggccaccgcc ggggacaccc accugggcgg ggaggacuuc      720

gacaaccggc ugguguccca cuucguggag gaguucaagc gcaagcacaa gaaggacauc      780

agccagaaca agcgggccgu ccgccggcuc cgcacggccu gcgagcgggc gaagcgcacc      840

cuguccagcu ccacccaggc caaccuggag aucgacagcc ucuacgaggg caucgacuuc      900

uacaccucca ucacgcgggc ccgcuucgag gagcugugcg ccgaccuguu ccggggcacc      960

cucgagccgg uggagaaggc ccugcgcgac gcgaagaugg acaaggccaa gauccacgac     1020

aucgugcugg ucgggggcag cacccggauc cccaaggugc agcgccuccu gcaggacuac     1080

uucaacgggc gggaccugaa caaguccauc aaccccgacg aggccgucgc cuacggcgcg     1140

gccgugcagg ccgccauccu caugggggac aagagcgaga aggugcagga ccugcugcuc     1200

cuggacgucg cgccccuguc ccucggccug gagaccgccg gcggggugau gacggcccug     1260

aucaagcgca acagcaccau cccgaccaag cagacccaga ucuucacgac cuacuccgac     1320

aaccagcccg gcgugcucau ccaggucuac gagggggagc gcgccaugac caaggacaac     1380

aaccugcugg gccgguucga ccucaccggg aucccgcccg cgccccgcgg cgugccccag     1440

aucgagguga cguucgacau cgacgccaac ggcauccuga acgucaccgc caccgacaag     1500

agcaccggga aggugaacaa gaucacgauc accaacgaca agggccggcu gagcaaggag     1560

gagaucgagc gcauggugcu cgacgccgag aaguacaagg ccgaggacga gguccagcgg     1620

gagaagaucg ccgccaagaa cgcgcuggag uccuacgccu ucaacaugaa guccguggug     1680

agcgacgagg ggcugaaggg caagaucagc gaguccgaca agaacaagau ccucgacaag     1740

ugcaacgagc ugcugagcug gcucgagguc aaccagcugg ccgagaagga cgaguucgac     1800

cacaagcgca aggagcugga gcagaugugc aaccccauca ucaccaagcu guaccagggc     1860

gggugcaccg gccccgccug cgggaccggc uacgugccgg ggcggcccgc gacgggcccc     1920

accaucgagg agguggacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1529
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt1)

<400>  1529
gggagaaagc uuaccaugag cgcccgcggc cccgccaucg ggaucgaccu gggcaccacc       60

uacuccugcg ugggggucuu ccagcacggc aagguggaga ucaucgcgaa cgaccagggg      120

aaccggacga ccccgagcua cguggccuuc accgacaccg agcgccucau cggcgacgcc      180

gccaagaacc aggucgccau gaaccccacg aacaccaucu ucgacgcgaa gcggcugauc      240

ggccgcaagu ucgaggacgc caccgugcag uccgacauga agcacuggcc cuuccgggug      300

gucagcgagg gcgggaagcc caagguccag guggaguaca agggggagac caagacguuc      360

uucccggagg agaucuccag cauggugcug accaagauga aggagaucgc cgaggccuac      420

cucggcggga aggugcacuc cgcggugauc accguccccg ccuacuucaa cgacagccag      480

cgccaggcca ccaaggacgc cggcacgauc accggccuga acgugcugcg gaucaucaac      540

gagcccaccg ccgcggccau cgccuacggg cucgacaaga agggcugcgc cgggggcgag      600

aagaacgugc ugaucuucga ccugggcggg ggcaccuucg acgucuccau ccucacgauc      660

gaggacggga ucuucgaggu caagagcacc gccggcgaca cccaccucgg gggcgaggac      720

uucgacaacc gcaugguguc ccaccuggcg gaggaguuca agcggaagca caagaaggac      780

aucggcccca acaagcgcgc cgugcggcgc cugcggaccg ccugcgagcg cgccaagcgg      840

acgcugagcu ccagcaccca ggccuccauc gagaucgaca gccuguacga ggggguggac      900

uucuacaccu ccaucacccg cgcgcgguuc gaggagcuca acgccgaccu guuccgcggc      960

acgcuggagc cgguggagaa ggcccuccgg gacgccaagc uggacaaggg gcagauccag     1020

gagaucgucc uggugggcgg gagcacccgc auccccaaga uccagaagcu ccugcaggac     1080

uucuucaacg gcaaggagcu gaacaagucc aucaaccccg acgaggccgu ggcguacggc     1140

gccgccgucc aggccgcgau ccucaucggg gacaagagcg agaacgugca ggaccugcug     1200

cuccuggacg ucacgccccu gagccucggc aucgagaccg ccgggggcgu gaugaccccg     1260

cugaucaagc ggaacaccac cauccccacc aagcagacgc agaccuucac caccuacucc     1320

gacaaccaga gcuccgugcu gguccaggug uacgaggggg agcgcgccau gacgaaggac     1380

aacaaccucc ugggcaaguu cgaccugacc ggcaucccgc ccgcgccccg cggggugccc     1440

cagaucgagg ucaccuucga caucgacgcc aacggcaucc ucaacgugac cgccgccgac     1500

aagagcaccg ggaaggagaa caagaucacg aucaccaacg acaagggccg gcuguccaag     1560

gacgacaucg accgcauggu gcaggaggcc gagcgguaca agagcgagga cgaggccaac     1620

cgcgaccggg ucgccgcgaa gaacgcccug gaguccuaca ccuacaacau caagcagacc     1680

guggaggacg agaagcuccg cggcaagauc agcgagcagg acaagaacaa gauccuggac     1740

aagugccagg aggugaucaa cuggcuggac cggaaccaga uggccgagaa ggacgaguac     1800

gagcacaagc agaaggagcu cgagcgcguc ugcaacccca ucaucuccaa gcuguaccag     1860

ggcgggcccg ggggcgggag cggcggcggg ggcuccgggg ccagcggcgg gccgacgauc     1920

gaggaggugg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  1530
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt1)

<400>  1530
gggagaaagc uuaccaugag cguggucggc aucgaccugg gguuccaguc cugcuacgug       60

gccguggccc gcgcgggcgg gaucgagacc aucgccaacg aguacagcga ccggugcacc      120

cccgccugca ucuccuucgg cccgaagaac cgcagcaucg gggccgccgc gaagucccag      180

gucaucagca acgccaagaa cacggugcag ggcuucaagc gguuccacgg ccgcgccuuc      240

uccgaccccu ucguggaggc cgagaagucc aaccucgcgu acgacaucgu ccagcugccc      300

accgggcuga ccggcaucaa ggugaccuac auggaggagg agcggaacuu cacgaccgag      360

caggucaccg ccaugcuccu gagcaagcug aaggagaccg ccgagagcgu gcucaagaag      420

cccguggugg acugcgucgu guccgugccg ugcuucuaca cggacgccga gcgccggagc      480

gucauggacg ccacccagau cgcggggcug aacugccugc gccucaugaa cgagaccacc      540

gccguggccc uggccuacgg caucuacaag caggaccugc ccgcccucga ggagaagccc      600

cggaacgugg ucuucgugga cauggggcac uccgcguacc aggugagcgu cugcgccuuc      660

aaccgcggca agcugaaggu gcuggccacg gccuucgaca ccacccucgg cgggcggaag      720

uucgacgagg ugcuggucaa ccacuucugc gaggaguucg gcaagaagua caagcuggac      780

aucaagucca agauccgcgc ccuccugcgg cugagccagg agugcgagaa gcucaagaag      840

cugauguccg cgaacgccag cgaccugccc cucuccaucg agugcuucau gaacgacgug      900

gacgucagcg ggaccaugaa ccgcggcaag uuccuggaga ugugcaacga ccugcucgcc      960

cggguggagc cgccccugcg cagcgugcug gagcagacga agcucaagaa ggaggacauc     1020

uacgccgucg agaucguggg cggggccacc cggauccccg cggugaagga gaagaucucc     1080

aaguucuucg gcaaggagcu gagcaccacc cugaacgccg acgaggccgu cacgcgcggg     1140

ugcgcccucc agugcgcgau ccuguccccc gccuucaagg ugcgggaguu cagcaucacc     1200

gacguggucc cguaccccau cucccugcgc uggaacagcc ccgccgagga gggcuccagc     1260

gacugcgagg uguucuccaa gaaccacgcc gcccccuuca gcaaggugcu caccuucuac     1320

cggaaggagc cguucacccu ggaggcguac uacuccagcc cccaggaccu gcccuacccc     1380

gacccggcca ucgcccaguu cuccguccag aaggugacgc cccagagcga cggguccagc     1440

uccaagguga aggucaaggu gcgcgugaac guccacggca ucuucagcgu guccagcgcc     1500

agccucgugg agguccacaa guccgaggag aacgaggagc ccauggagac cgaccagaac     1560

gccaaggagg aggagaagau gcaggucgac caggaggagc cccacgugga ggagcagcag     1620

cagcagaccc cggcggagaa caaggccgag agcgaggaga uggagaccuc ccaggccggc     1680

agcaaggaca agaagaugga ccagccgccc caggccaaga aggccaaggu gaagacgucc     1740

accguggacc ugcccaucga gaaccagcug cucuggcaga ucgaccgcga gaugcugaac     1800

cuguacaucg agaacgaggg gaagaugauc augcaggaca agcucgagaa ggagcggaac     1860

gacgcgaaga acgccgugga ggaguacguc uacgagaugc gcgacaagcu gagcggcgag     1920

uacgagaagu ucguguccga ggacgaccgg aacagcuuca cccugaagcu cgaggacacc     1980

gagaacuggc uguacgagga cggggaggac cagcccaagc aggucuacgu ggacaagcug     2040

gccgagcuga agaaccucgg ccagcccauc aagauccgcu uccaggaguc cgaggagcgg     2100

cccaagcugu ucgaggagcu ggggaagcag auccagcagu acaugaagau caucagcucc     2160

uucaagaaca aggaggacca guacgaccac cucgacgccg cggacaugac gaagguggag     2220

aaguccacca acgaggccau ggaguggaug aacaacaagc ugaaccugca gaacaagcag     2280

agccucacca uggacccggu ggucaagagc aaggagaucg aggccaagau caaggagcug     2340

accuccacgu gcagccccau caucuccaag cccaagccca agguggagcc gcccaaggag     2400

gagcagaaga acgccgagca gaacggcccc guggacggcc agggggacaa ccccggcccg     2460

caggccgcgg agcaggggac cgacaccgcc guccccagcg acagcgacaa gaagcugccc     2520

gagauggaca ucgacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  1531
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt1)

<400>  1531
gggagaaagc uuaccaugag cguggucggc aucgaccugg gguuccucaa cugcuacauc       60

gccguggccc gcuccggcgg gaucgagacc aucgcgaacg aguacagcga ccggugcacc      120

cccgccugca ucucccuggg cagccgcacg cgggccaucg ggaacgccgc caagucccag      180

aucgugacca acguccgcaa caccauccac ggcuucaaga agcugcacgg ccggagcuuc      240

gacgacccga ucgugcagac cgagcgcauc cggcuccccu acgagcugca gaagaugccc      300

aacggguccg cgggcgugaa gguccgcuac cuggaggagg agcggcccuu cgccaucgag      360

caggucacgg ggaugcuccu ggccaagcug aaggagacca gcgagaacgc ccucaagaag      420

ccgguggcgg acugcgugau cuccaucccc agcuucuuca ccgacgccga gcgccggucc      480

gugauggccg ccgcccaggu ggcgggccug aacugccugc gccucaugaa cgagaccacg      540

gccgucgccc uggccuacgg gaucuacaag caggaccugc cgccccucga cgagaagccc      600

cggaacgugg uguucaucga caugggccac agcgccuacc agguccuggu gugcgcguuc      660

aacaagggca agcugaaggu gcucgccacc accuucgacc ccuaccucgg gggccgcaac      720

uucgacgagg cccuggucga cuacuucugc gacgaguuca agaccaagua caagaucaac      780

gugaaggaga acucccgggc ccugcugcgc cuguaccagg agugcgagaa gcucaagaag      840

cugaugagcg ccaacgcguc cgaccugccc cucaacaucg agugcuucau gaacgaccug      900

gacgugagcu ccaagaugaa ccgggcccag uucgagcagc ugugcgccag ccuccuggcc      960

cgcgucgagc ccccgcugaa ggccgugaug gagcaggcga accuccagcg ggaggacauc     1020

uccagcaucg agaucgucgg gggcgccacg cgcauccccg ccgugaagga gcagaucacc     1080

aaguucuucc ugaaggacau cagcaccacc cugaacgccg acgaggcggu ggcccggggc     1140

ugcgcccucc agugcgccau ccuguccccc gccuucaagg uccgcgaguu cagcaucacg     1200

gaccuggugc ccuacuccau cacccuccgc uggaagacca gcuucgagga cggguccggc     1260

gagugcgagg uguucugcaa gaaccacccg gcgcccuuca gcaaggucau caccuuccac     1320

aagaaggagc ccuucgagcu ggaggccuuc uacacgaacc ugcacgaggu gcccuacccg     1380

gacgcccgga ucggguccuu caccauccag aacguguucc cccagagcga cggcgacucc     1440

agcaagguca aggugaaggu gcgcgucaac auccacggga ucuucuccgu ggccagcgcc     1500

uccgugaucg agaagcagaa ccucgagggc gaccacagcg acgcgcccau ggagaccgag     1560

accuccuuca agaacgagaa caaggacaac auggacaaga ugcaggucga ccaggaggag     1620

ggccaccaga agugccacgc cgagcacacg cccgaggagg agaucgacca caccggggcc     1680

aagaccaaga gcgccguguc cgacaagcag gaccggcuga accagacccu gaagaagggc     1740

aaggucaaga gcaucgaccu cccgauccag uccagccugu gccgccagcu ggggcaggac     1800

cuccugaaca gcuacaucga gaacgagggc aagaugauca ugcaggacaa gcuggagaag     1860

gagcggaacg acgccaagaa cgcgguggag gaguacgugu acgacuuccg cgaccggcug     1920

gggacggugu acgagaaguu caucaccccc gaggaccucu ccaagcugag cgccguccug     1980

gaggacaccg agaacuggcu cuacgaggac ggcgaggacc agcccaagca ggucuacgug     2040

gacaagcugc aggagcugaa gaaguacggc cagcccaucc agaugaagua cauggagcac     2100

gaggagcgcc cgaaggcccu caacgaccug gggaagaaga uccagcuggu gaugaaggug     2160

aucgaggccu accggaacaa ggacgagcgc uacgaccacc ucgaccccac cgagauggag     2220

aagguggaga agugcaucuc cgacgcgaug agcuggcuga acuccaagau gaacgcccag     2280

aacaagcuga gccucacgca ggaccccguc gugaaggugu ccgagaucgu cgccaagagc     2340

aaggagcugg acaacuucug caacccgauc aucuacaagc ccaagcccaa ggccgaggug     2400

cccgaggaca agccgaaggc caacuccgag cacaacggcc ccauggacgg gcagagcggc     2460

accgagacca aguccgacag caccaaggac uccagccagc acacgaaguc cagcggggag     2520

auggaggugg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  1532
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt1)

<400>  1532
gggagaaagc uuaccaugaa gcugagccuc guggccgcca ugcugcugcu ccuguccgcg       60

gcccgcgccg aggaggagga caagaaggag gacgucggca ccgugguggg gaucgaccug      120

ggcaccacgu acagcugcgu cgggguguuc aagaacggcc ggguggagau caucgccaac      180

gaccagggga accgcaucac ccccuccuac gucgccuuca ccccggaggg cgagcggcuc      240

aucggcgacg cggccaagaa ccagcugacc agcaaccccg agaacacggu guucgacgcc      300

aagcgccuga ucgggcggac cuggaacgac cccuccgugc agcaggacau caaguuccuc      360

cccuucaagg ucguggagaa gaagaccaag ccguacaucc agguggacau cggcgggggc      420

cagaccaaga cguucgcccc cgaggagauc agcgcgaugg uccugaccaa gaugaaggag      480

accgccgagg ccuaccuggg gaagaaggug acccacgccg uggucacggu gcccgccuac      540

uucaacgacg cgcagcgcca ggccaccaag gacgccggca ccaucgccgg ccucaacgug      600

augcggauca ucaacgagcc caccgccgcg gccaucgccu acgggcugga caagcgcgag      660

ggcgagaaga acauccuggu cuucgaccuc gggggcggca cguucgacgu gucccugcug      720

accaucgaca acgggguguu cgaggucgug gccaccaacg gcgacaccca ccucgggggc      780

gaggacuucg accagcgggu gauggagcac uucaucaagc uguacaagaa gaagacgggg      840

aaggacgucc gcaaggacaa ccgggccgug cagaagcugc gccgggaggu cgagaaggcg      900

aagcgcgccc ucagcuccca gcaccaggcc cggaucgaga ucgagagcuu cuacgagggc      960

gaggacuucu ccgagacccu gacccgcgcc aaguucgagg agcugaacau ggaccucuuc     1020

cggagcacca ugaagccggu gcagaaggug cuggaggacu ccgaccugaa gaaguccgac     1080

aucgacgaga ucguccucgu gggcgggagc acgcgcaucc ccaagaucca gcagcuggug     1140

aaggaguucu ucaacggcaa ggagcccagc cgggggauca accccgacga ggccgucgcg     1200

uacggcgccg ccgugcaggc cggggugcug uccggcgacc aggacaccgg cgaccucguc     1260

cugcuggacg ugugcccgcu cacccugggg aucgagaccg ugggcggggu caugacgaag     1320

cugauccccc gcaacaccgu ggugcccacc aagaaguccc agaucuucag caccgcgagc     1380

gacaaccagc ccacggucac caucaaggug uacgagggcg agcggccgcu caccaaggac     1440

aaccaccucc uggggaccuu cgaccugacg ggcaucccgc ccgcgccccg cggcgugccc     1500

cagaucgagg ucaccuucga gaucgacgug aacgggaucc ugcgcgugac cgccgaggac     1560

aagggcaccg ggaacaagaa caagaucacc aucacgaacg accagaaccg gcugaccccc     1620

gaggagaucg agcgcauggu caacgacgcc gagaaguucg ccgaggagga caagaagcuc     1680

aaggagcgga ucgacacccg caacgagcug gagagcuacg ccuacucccu gaagaaccag     1740

aucggcgaca aggagaagcu cggcgggaag cugagcuccg aggacaagga gaccauggag     1800

aaggccgugg aggagaagau cgaguggcug gagagccacc aggacgccga caucgaggac     1860

uucaaggcca agaagaagga gcucgaggag aucgugcagc ccaucaucuc caagcuguac     1920

ggcagcgccg ggcccccgcc cacgggcgag gaggacaccg cggagaagga cgagcuguga     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  1533
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt1)

<400>  1533
gggagaaagc uuaccaugca ggcgccccgc gagcuggccg ugggcaucga ccucgggacc       60

accuacagcu gcgucggcgu guuccagcag gggcgggugg agauccuggc caacgaccag      120

ggcaaccgca cgaccccguc cuacgucgcc uucaccgaca ccgagcggcu ggugggggac      180

gccgccaaga gccaggccgc gcucaacccc cacaacacgg uguucgacgc caagcgccug      240

aucggccgga aguucgccga caccaccguc caguccgaca ugaagcacug gcccuuccgc      300

guggugagcg agggcgggaa gcccaagguc cgggugugcu accgcggcga ggacaagacc      360

uucuacccgg aggagaucuc cagcauggug cuguccaaga ugaaggagac ggccgaggcg      420

uaccucgggc agcccgucaa gcacgccgug aucaccgugc ccgccuacuu caacgacagc      480

cagcggcagg ccaccaagga cgccggcgcg aucgccgggc ugaacguccu gcgcaucauc      540

aacgagccca ccgccgccgc caucgcguac ggccucgacc ggcgcggcgc cggggagcgg      600

aacgugcuga ucuucgaccu gggcgggggc acguucgacg uguccguccu cagcaucgac      660

gccggcgugu ucgaggugaa ggccaccgcc ggggacaccc accugggcgg ggaggacuuc      720

gacaaccgcc uggucaacca cuucauggag gaguuccggc gcaagcacgg caaggaccuc      780

uccgggaaca agcgggcgcu gcgccggcug cgcaccgccu gcgagcgggc caagcgcacg      840

cucagcucca gcacccaggc cacccuggag aucgacuccc uguucgaggg cguggacuuc      900

uacaccagca ucacgcgcgc ccgguucgag gagcucugcu ccgaccuguu ccgcagcacc      960

cuggagccgg uggagaaggc gcuccgggac gccaagcugg acaaggccca gauccacgac     1020

gucgugcugg ucggcggguc cacccgcauc cccaaggugc agaagcuccu gcaggacuuc     1080

uucaacggca aggagcugaa caagagcauc aaccccgacg aggccguggc guacggggcc     1140

gccguccagg ccgccgugcu caugggcgac aagugcgaga aggugcagga ccugcugcuc     1200

cuggacgucg cgccccugag ccucgggcug gagaccgccg gcggcgugau gacgacccug     1260

auccagcgga acgccaccau cccgaccaag cagacgcaga ccuucaccac cuacuccgac     1320

aaccagcccg ggguguucau ccaggucuac gagggcgagc gcgccaugac gaaggacaac     1380

aaccuccugg ggcgguucga gcugagcggc aucccgcccg cgccccgcgg ggugccccag     1440

aucgagguga ccuucgacau cgacgccaac ggcauccucu ccgucaccgc caccgaccgg     1500

agcacgggca aggccaacaa gaucaccauc accaacgaca aggggcgccu guccaaggag     1560

gagguggagc ggauggugca cgaggccgag caguacaagg ccgaggacga ggcgcagcgc     1620

gaccgggucg ccgccaagaa cagccuggag gcccacgugu uccacgugaa gggcucccuc     1680

caggaggaga gccugcgcga caagaucccc gaggaggacc ggcgcaagau gcaggacaag     1740

ugccgggagg uccuggcgug gcucgagcac aaccagcugg ccgagaagga ggaguacgag     1800

caccagaagc gcgagcugga gcagaucugc cggcccaucu ucucccgccu guacgggggc     1860

ccgggcgugc ccgggggcag cuccugcggg acccaggccc gccagggcga ccccagcacc     1920

gggcccauca ucgaggaggu ggacugagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  1534
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt1)

<400>  1534
gggagaaagc uuaccaugca ggcgccccgc gagcuggccg ugggcaucga ccucgggacc       60

accuacagcu gcgucggcgu guuccagcag gggcgggugg agauccuggc caacgaccag      120

ggcaaccgca cgaccccguc cuacgucgcc uucaccgaca ccgagcggcu ggugggggac      180

gccgccaaga gccaggccgc gcucaacccc cacaacacgg uguucgacgc caagcgccug      240

aucggccgga aguucgccga caccaccguc caguccgaca ugaagcacug gcccuuccag      300

guggugagcg agggcgggaa gcccaagguc cgcgugugcu accggggcga ggacaagacc      360

uucuacccgg aggagaucuc cagcauggug cuguccaaga ugaaggagac ggccgaggcg      420

uaccucgggc agcccgucaa gcacgccgug aucaccgugc ccaccuacuu cagcaacucc      480

cagcgccagg ccaccaagga cgccggcgcc aucgcggggc ugaagguccu gcccaucauc      540

aacgaggcca cggccgccgc caucgcguac ggccucgacc ggcgcggcgc cgggaagcgg      600

aacgugcuga ucuucgaccu gggcgggggc accuucgacg ugagcguccu cuccaucgac      660

gccggcgugu ucgaggugaa ggccaccgcc ggggacaccc accugggcgg ggaggacuuc      720

gacaaccgcc uggucaacca cuucauggag gaguuccggc gcaagcacgg caaggaccuc      780

agcgggaaca agcgggcgcu gcgccggcug cgcacggccu gcgagcgggc caagcgcacc      840

ccguccagcu ccacccaggc cacccucgag aucgacagcc uguucgaggg cguggacuuc      900

uacaagucca ucacgcgggc ccgcuucgag gagcugugca gcgaccucuu ccgcuccacc      960

cuggagcccg uggagaaggc gcugcgggac gccaagcucg acaaggccca gauccacgac     1020

uucguccugg gcgggggccu gcacagccac ccccaggggg ccgagguggc ggccggccuc     1080

cugcagcgcc agggggccga gcaggagcac cagcccugag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  1535
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt1)

<400>  1535
gggagaaagc uuaccaugag caagggcccc gccgugggga ucgaccuggg caccaccuac       60

uccugcgucg ggguguucca gcacggcaag guggagauca ucgccaacga ccaggggaac      120

cgcacgaccc ccagcuacgu cgcguucacc gacaccgagc ggcucaucgg cgacgccgcc      180

aagaaccagg uggccaugaa ccccacgaac accguguucg acgccaagcg ccugaucggc      240

cggcgcuucg acgacgcggu cgugcagucc gacaugaagc acuggcccuu cauggugguc      300

aacgacgccg ggcggcccaa gguccaggug gaguacaagg gcgagaccaa gagcuucuac      360

ccggaggagg uguccagcau ggugcugacc aagaugaagg agaucgccga ggccuaccuc      420

gggaagacgg ugaccaacgc ggucgugacc gugcccgccu acuucaacga cucccagcgc      480

caggccacca aggacgccgg cacgaucgcc gggcugaacg uccugcggau caucaacgag      540

cccaccgcgg ccgccaucgc cuacggccuc gacaagaagg ugggcgccga gcgcaacgug      600

cugaucuucg accucggggg cgggaccuuc gacgucagca uccugaccau cgaggacggc      660

aucuucgagg ugaaguccac ggcgggcgac acccaccucg ggggcgagga cuucgacaac      720

cggaugguga accacuucau cgccgaguuc aagcgcaagc acaagaagga caucagcgag      780

aacaagcggg ccguccgccg gcugcgcacc gccugcgagc gggccaagcg cacccugucc      840

agcuccacgc aggcgagcau cgagaucgac ucccuguacg aggggaucga cuucuacacc      900

agcaucaccc gggcccgcuu cgaggagcug aacgccgacc ucuuccgggg cacccuggac      960

cccguggaga aggcccugcg cgacgccaag cucgacaagu cccagaucca cgacaucguc     1020

cuggucgggg gcagcacgcg gaucccgaag auccagaagc ugcuccagga cuucuucaac     1080

ggcaaggagc ugaacaaguc caucaacccc gacgaggcgg uggccuacgg ggccgccgug     1140

caggcggcca uccugagcgg cgacaagagc gagaacgugc aggaccuccu gcugcucgac     1200

gugacgcccc ugucccuggg gaucgagacc gccggcgggg ucaugaccgu gcucaucaag     1260

cgcaacacca ccauccccac caagcagacc cagacguuca ccaccuacag cgacaaccag     1320

ccgggcgugc ugauccaggu cuacgagggc gagcgcgcca ugaccaagga caacaaccug     1380

cucgggaagu ucgagcugac gggcaucccg cccgcgcccc gcggggugcc ccagaucgag     1440

gugaccuucg acaucgacgc caacggcauc cugaacgucu ccgccgugga caagagcacc     1500

gggaaggaga acaagaucac caucaccaac gacaagggcc ggcucuccaa ggaggacauc     1560

gagcggaugg ugcaggaggc cgagaaguac aaggccgagg acgagaagca gcgcgacaag     1620

gucagcucca agaacagccu ggaguccuac gccuucaaca ugaaggcgac gguggaggac     1680

gagaagcugc agggcaagau caacgacgag gacaagcaga agauccucga caagugcaac     1740

gagaucauca acuggcugga caagaaccag accgccgaga aggaggaguu cgagcaccag     1800

cagaaggagc uggagaaggu gugcaacccc aucaucacca agcucuacca gagcgccggg     1860

ggcaugcccg ggggcaugcc cggcggguuc ccgggcgggg gcgccccgcc cuccgggggc     1920

gccagcuccg gccccaccau cgaggagguc gacugaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  1536
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt1)

<400>  1536
gggagaaagc uuaccaugau cagcgccucc cgcgccgcgg ccgcccggcu ggugggcgcc       60

gccgcgagcc gcgggcccac cgccgcccgg caccaggacu ccuggaacgg ccucagccac      120

gaggccuucc gccuggucuc ccggcgcgac uacgcgagcg aggccaucaa gggggccgug      180

gugggcaucg accuggggac cacgaacucc ugcgucgccg ugauggaggg caagcaggcc      240

aaggugcucg agaacgcgga gggcgcccgg accaccccga gcgucguggc cuucaccgcc      300

gacggggagc gccugguggg caugcccgcc aagcggcagg cggucacgaa ccccaacaac      360

accuucuacg ccaccaagcg ccugaucggg cggcgcuacg acgaccccga ggugcagaag      420

gacaucaaga acgugccguu caagaucguc cgggccucca acggcgacgc cuggguggag      480

gcccacggga agcucuacag ccccucccag aucggcgcgu ucgugcugau gaagaugaag      540

gagaccgccg agaacuaccu gggccacacg gccaagaacg ccgucaucac cgugcccgcc      600

uacuucaacg acagccagcg ccaggcgacc aaggacgccg ggcagaucuc cggccucaac      660

gugcugcggg ucaucaacga gcccaccgcc gccgcgcugg ccuacgggcu cgacaagagc      720

gaggacaagg ugaucgccgu guacgaccug ggcggcggga cguucgacau cuccauccug      780

gagauccaga agggcgucuu cgaggucaag agcaccaacg gggacaccuu ccucggcggg      840

gaggacuucg accaggcccu gcugcgccac aucgugaagg aguucaagcg ggagaccggc      900

guggaccuca cgaaggacaa cauggcccug cagcgcgugc gggaggcggc cgagaaggcc      960

aagugcgagc uguccagcuc cguccagacc gacaucaacc ucccguaccu gaccauggac     1020

agcagcggcc ccaagcaccu gaacaugaag cucacccgcg cccaguucga ggggaucgug     1080

acggaccuga uccggcgcac caucgccccc ugccagaagg cgaugcagga cgccgaggug     1140

uccaagagcg acaucggcga ggucauccug gucgggggca ugacccgcau gcccaaggug     1200

cagcagaccg ugcaggaccu cuucgggcgg gccccgucca aggccgugaa ccccgacgag     1260

gccguggcga ucggcgccgc cauccagggc gggguccugg ccggcgacgu gacggacgug     1320

cugcuccugg acgucacgcc ccugagccuc gggaucgaga cccugggcgg gguguucacc     1380

aagcugauca accgcaacac caccaucccc accaagaagu cccagguguu cagcaccgcg     1440

gccgacggcc agacgcaggu cgagaucaag gugugccagg gcgagcggga gauggccggg     1500

gacaacaagc uccugggcca guucacccug aucgggaucc cgcccgcgcc ccgcggcgug     1560

ccccagaucg aggucaccuu cgacaucgac gccaacggca ucgugcacgu guccgccaag     1620

gacaagggga ccggccggga gcagcagauc gucauccaga gcuccggggg ccucagcaag     1680

gacgacaucg agaacauggu gaagaacgcc gagaaguacg ccgaggagga ccgccggaag     1740

aaggagcgcg uggaggccgu caacauggcc gaggggauca uccacgacac ggagaccaag     1800

auggaggagu ucaaggacca gcugccggcg gacgagugca acaagcugaa ggaggagauc     1860

uccaagaugc gggagcuccu ggcccgcaag gacagcgaga ccggcgagaa cauccggcag     1920

gccgccucca gccugcagca ggccucccuc aagcuguucg agauggcgua caagaagaug     1980

gccagcgagc gcgagggcuc cgggagcucc ggcaccgggg agcagaagga ggaccagaag     2040

gaggagaagc agugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  1537
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt1)

<400>  1537
gggagaaagc uuaccauggc cgacaaggag gccggcggga gcgacggccc ccgcgagacc       60

gcgccgaccu ccgccuacag cucccccgcc cggagccugg gggacacggg caucacgccc      120

cucuccccca gccacaucgu gaacgacacc gacuccaacg ucagcgagca gcaguccuuc      180

cugguggugg ucgccgugga cuucgggacc accagcuccg gcuacgccua cagcuucacc      240

aaggagccgg agugcaucca cgugaugcgc cggugggagg gcggggaccc cggcgucucc      300

aaccagaaga cccccaccac gauccugcuc acccccgagc gcaaguucca cagcuucggg      360

uacgcggccc gggacuucua ccacgaccug gacccgaacg aggccaagca guggcuguac      420

cucgagaagu ucaagaugaa gcugcacacc accggcgacc ugacgaugga caccgaccuc      480

accgccgcga acgggaagaa ggugaaggcc cuggagaucu ucgccuacgc ccugcaguac      540

uucaaggagc aggcccucaa ggagcugucc gaccaggcgg gcagcgaguu cgagaacucc      600

gacgugcgcu gggucaucac cgugcccgcc aucuggaagc agcccgccaa gcaguucaug      660

cggcaggccg ccuaccaggc gggccuggcc agccccgaga acuccgagca gcucaucauc      720

gcccuggagc cggaggccgc cagcaucuac ugccgcaagc ugcggcucca ccagaugauc      780

gagcugagcu ccaaggcggc cgugaacggg uacagcggcu ccgacacggu cggggccggc      840

uucacccagg ccaaggagca cauccgccgg aaccgccaga gccggaccuu ccugguggag      900

aacgugaucg gcgagaucug guccgagcuc gaggaggggg acaaguacgu cgugguggac      960

agcggcgggg gcaccgucga ccugacggug caccagaucc gccugcccga ggggcaccuc     1020

aaggagcugu acaaggccac cggcggcccc uacggguccc ugggcgugga cuacgaguuc     1080

gagaagcucc uguacaagau cuucggggag gacuucaucg agcaguucaa gaucaagcgg     1140

cccgcggccu gggucgaccu gaugaucgcc uucgagagcc gcaagcgggc cgcggccccg     1200

gaccgcacca acccccucaa caucacccug cccuucuccu ucaucgacua cuacaagaag     1260

uuccggggcc acagcgugga gcacgcccug cgcaagucca acguggacuu cgucaagugg     1320

agcucccagg ggaugcuccg gaugagcccc gacgccauga acgcccuguu caagccgacg     1380

aucgacucca ucaucgagca ccuccgcgac cuguuccaga agcccgaggu gagcaccguc     1440

aaguuccugu uccugguggg cggcuucgcg gaggcgcccc uccugcagca ggccgugcag     1500

gccgccuucg gggaccagug ccgcaucauc aucccccagg acgucggccu gaccauccuc     1560

aagggggccg ugcuguucgg ccuggacccg gccgugauca agguccggcg cagcccccuc     1620

accuacgggg ugggcgugcu gaaccgguac gucgagggca agcacccgcc cgagaagcug     1680

cucgugaagg acgggacgcg cuggugcacc gacguguucg acaaguucau cuccgccgac     1740

caguccgucg cccugggcga gcuggugaag cggagcuaca cccccgccaa gcccagccag     1800

cuggugaucg ucaucaacau cuacuccagc gagcacgaca acguguccuu caucaccgac     1860

cccgggguga agaagugcgg cacgcuccgc cuggaccuga ccggcaccag cgggaccgcg     1920

gucccggccc ggcgcgagau ccagacgcuc augcaguucg gcgacaccga gaucaaggcc     1980

accgccaucg acaucgcgac cuccaagagc gugaaggugg ggaucgacuu ccugaacuac     2040

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  1538
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt1)

<400>  1538
gggagaaagc uuaccaugcu ggccgugccc gagaugggcc uccaggggcu guacaucggc       60

agcucccccg agcgcagccc cguccccucc ccgcccggga gcccccggac ccaggagucc      120

ugcggcaucg ccccgcugac ccccagccag ucccccaagc ccgaggugcg cgcgccccag      180

caggccagcu ucuccguggu cguggccauc gacuucggga cgaccagcuc cggcuacgcc      240

uucagcuucg ccuccgaccc cgaggcgauc cacaugaugc ggaaguggga gggcggggac      300

ccgggcgugg cccaccagaa gaccccgacc ugccuccugc ugacgcccga gggggccuuc      360

cacagcuucg gcuacaccgc ccgcgacuac uaccacgacc ucgaccccga ggaggcgcgg      420

gacuggcugu acuucgagaa guucaagaug aagauccacu ccgccaccga ccugacccuc      480

aagacgcagc uggaggccgu caacgggaag accaugcccg cccuggaggu guucgcccac      540

gcgcuccgcu ucuuccggga gcacgcccug caggagcugc gcgagcagag ccccucccuc      600

cccgagaagg acaccgugcg guggguccug accgugcccg ccaucuggaa gcagccggcc      660

aagcaguuca ugcgcgaggc cgcguaccug gccggccucg ugagccggga gaacgccgag      720

cagcugcuga ucgcccucga gcccgaggcc gcguccgucu acugccgcaa gcugcggcug      780

caccagcucc uggaccugag cggccgcgcc cccgggggcg ggcggcucgg cgagcgccgg      840

agcaucgacu ccagcuuccg ccaggcccgg gagcagcugc gccggucccg ccacagccgc      900

acguuccugg uggaguccgg cgugggggag cucugggccg agaugcaggc cggcgaccgg      960

uacgucgugg cggacugcgg gggcgggacc guggaccuga ccguccacca gcuggagcag     1020

ccccacggca cccucaagga gcuguacaag gccagcggcg ggccguacgg cgccgugggg     1080

guggaccugg ccuucgagca gcuccugugc cgcaucuucg gcgaggacuu caucgcgacg     1140

uucaagcggc agcgccccgc cgccuggguc gaccugacca ucgccuucga ggcccggaag     1200

cgcaccgcgg ggccccaccg ggccggcgcc cucaacaucu cccugcccuu cagcuucauc     1260

gacuucuacc gcaagcagcg gggccacaac guggagaccg cccugcgccg guccagcgug     1320

aacuucguca agugguccag ccaggggaug cuccgcaugu ccugcgaggc caugaacgag     1380

cuguuccagc cgacggugag cggcaucauc cagcacaucg aggcgcugcu cgcccggccc     1440

gagguccagg gggugaagcu gcuguuccuc gugggcgggu ucgccgaguc cgccguccug     1500

cagcacgccg ugcaggcggc ccugggcgcc cgcggccugc ggguggucgu gccccacgac     1560

guggggcuca ccauccugaa gggcgccguc cuguucgggc aggcgccggg cguggugcgc     1620

guccggcgca gcccccucac cuacggcgug ggggugcuga accgguucgu ccccggccgc     1680

cacccgcccg agaagcugcu cgugcgcgac gggcggcgcu ggugcaccga cguguucgag     1740

cgguucgucg ccgccgagca guccguggcc cugggcgagg aggugcgccg gagcuacugc     1800

cccgcccgcc ccgggcagcg gcgcguccug aucaaccucu acugcugcgc ggccgaggac     1860

gcccgguuca ucacggaccc cggcgugcgc aagugcggcg cccugucccu ggagcucgag     1920

ccggccgacu gcgggcagga caccgcgggc gccccgcccg ggcggcgcga gauccgggcc     1980

gccaugcagu ucggcgacac cgagaucaag gugaccgccg ucgacgugag cacgaaccgc     2040

agcgugcggg cguccaucga cuuccugagc aacugaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  1539
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt1)

<400>  1539
gggagaaagc uuaccauggc ccgggagaug accauccugg gcagcgccgu gcucacccug       60

cugcucgcgg gguaccuggc ccagcaguac cugccccucc cgacgcccaa ggucaucggc      120

aucgaccugg ggaccaccua cugcuccgug ggcguguucu uccccgggac cggcaagguc      180

aaggugaucc ccgacgagaa cggccacauc agcaucccgu ccauggugag cuucacggac      240

aacgacgucu acguggggua cgaguccgug gagcuggccg acagcaaccc ccagaacacc      300

aucuacgacg ccaagcgguu caucggcaag aucuucaccg ccgaggagcu cgaggcggag      360

aucgggcgcu accccuucaa gguccugaac aagaacggca ugguggaguu cuccgugacc      420

agcaacgaga cgaucaccgu cucccccgag uacgugggga gccggcugcu ccugaagcug      480

aaggagaugg ccgaggccua ccucggcaug ccgguggcca acgcggucau cuccgugccc      540

gccgaguucg accugaagca gcgcaacagc accaucgagg ccgccaaccu ggccggccuc      600

aagauccugc gggugaucaa cgagcccacc gcggccgcca uggccuacgg gcugcacaag      660

gccgacgucu uccacgugcu cgugaucgac cugggcgggg gcacgcugga cgucucccuc      720

cugaacaagc agggcgggau guuccugacc cgcgcgauga gcggcaacaa caagcucggg      780

ggccaggacu ucaaccagcg gcugcugcag uaccucuaca agcagaucua ccagaccuac      840

ggguucgugc ccucccgcaa ggaggagauc caccggcugc gccaggccgu ggagaugguc      900

aagcugaacc ucacccugca ccagagcgcc cagcuguccg ugcuccugac ggucgaggag      960

caggaccgga aggagccgca cagcuccgac accgagcugc ccaaggacaa gcucagcagc     1020

gccgacgacc accgcgugaa cuccggcuuc ggccgggggc ugagcgacaa gaaguccggc     1080

gagagccagg ugcuguucga gaccgagauc ucccgcaagc uguucgacac ccugaacgag     1140

gaccuguucc agaagauccu cguccccauc cagcaggucc ugaaggaggg gcaccuggag     1200

aagacggaga ucgacgaggu ggugcucgug ggcgggagca cccggauccc ccgcauccgc     1260

caggugaucc aggaguucuu cggcaaggac ccgaacaccu ccgucgaccc cgaccuggcc     1320

guggugaccg gcgucgcgau ccaggccggg aucgacggcg ggagcuggcc ccuccaggug     1380

uccgcccugg agauccccaa caagcaccuc cagaagacga acuucaacug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  1540
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt1)

<400>  1540
gggagaaagc uuaccauggc cgccaucggc gugcaccugg ggugcaccag cgcgugcguc       60

gccguguaca aggacggccg cgccggggug gucgccaacg acgccggcga ccgggugacc      120

cccgcggugg ucgccuacuc cgagaacgag gagaucgugg ggcucgccgc caagcagagc      180

cgcauccgga acaucuccaa cacggugaug aaggucaagc agauccuggg ccgcagcucc      240

agcgacccgc aggcgcagaa guacaucgcc gaguccaagu gccuggugau cgagaagaac      300

ggcaagcucc gguacgagau cgacaccggg gaggagacca aguucgugaa ccccgaggac      360

gucgcccgcc ugaucuucag caagaugaag gagaccgccc acuccgugcu gggcagcgac      420

gccaacgacg uggucaucac ggugcccuuc gacuucgggg agaagcagaa gaacgcgcuc      480

ggcgaggccg cccgggccgc cggguucaac gugcugcgcc ugauccacga gcccuccgcg      540

gcccuccugg ccuacggcau cggccaggac agcccgaccg ggaaguccaa cauccugguc      600

uucaagcucg gcgggaccag ccugucccug agcgugaugg aggugaacuc cggcaucuac      660

cggguccuca gcaccaacac ggacgacaac aucggcgggg cccacuucac cgagacccug      720

gcccaguacc uggcguccga guuccagcgc agcuucaagc acgacgugcg gggcaacgcc      780

cgcgccauga ugaagcucac caacagcgcc gagguggcca agcacucccu gagcacgcug      840

ggguccgcga acugcuuccu cgacagccug uacgagggcc aggacuucga cugcaacguc      900

ucccgggccc gcuucgagcu gcucugcagc ccccuguuca acaagugcau cgaggccauc      960

cgggggcugc ucgaccagaa cggcuucacc gccgacgaca ucaacaaggu gguccugugc     1020

ggcgggucca gccgcauccc caagcugcag cagcucauca aggaccuguu ccccgcggug     1080

gagcugcuca acuccauccc gcccgacgag gugaucccca ucggcgccgc caucgaggcc     1140

gggauccuga ucggcaagga gaaccugcuc gucgaggaca gccugaugau cgagugcucc     1200

gcccgggaca uccuggugaa ggggguggac gagagcggcg cgucccgcuu caccguccuc     1260

uuccccagcg gcaccccgcu gcccgcccgg cgccagcaca cgcugcaggc ccccgggucc     1320

aucagcuccg ugugccucga gcuguacgag agcgacggca agaacuccgc caaggaggag     1380

accaaguucg cccagguggu ccugcaggac cucgacaaga aggagaacgg gcugcgggac     1440

auccuggcgg ugcucaccau gaagcgcgac ggcagccugc acgugaccug cacggaccag     1500

gagaccggga agugcgaggc caucagcauc gagaucgccu ccugaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  1541
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt1)

<400>  1541
gggagaaagc uuaccaugag cguggucggc cuggacgugg ggucccagag cugcuacauc       60

gccguggccc gcgcgggcgg gaucgagacc aucgccaacg aguucuccga ccggugcacc      120

cccagcguca ucuccuucgg cagcaagaac cgcaccaucg ggguggccgc caagaaccag      180

cagaucaccc acgccaacaa caccgugucc aacuucaagc gguuccacgg ccgcgcguuc      240

aacgacccgu ucauccagaa ggagaaggag aaccucagcu acgaccuggu cccccugaag      300

aacggcgggg ugggcaucaa ggugauguac augggggagg agcaccucuu cuccgucgag      360

cagaucaccg ccaugcugcu gacgaagcuc aaggagaccg ccgagaacag ccugaagaag      420

cccgugaccg acugcgugau cuccgucccc agcuucuuca ccgacgccga gcggcgcucc      480

gugcuggacg cggcccagau cgugggccuc aacugccugc ggcugaugaa cgacaugacg      540

gccgucgccc ucaacuacgg gaucuacaag caggaccugc cgagccugga cgagaagccc      600

cgcaucgugg uguucgucga caugggccac uccgccuucc aggugagcgc gugcgccuuc      660

aacaagggca agcucaaggu gcuggggacc gccuucgacc ccuuccuggg cgggaagaac      720

uucgacgaga agcucgucga gcacuucugc gccgaguuca agaccaagua caagcuggac      780

gccaagucca agauccgggc gcugcuccgc cuguaccagg agugcgagaa gcugaagaag      840

cucaugagcu ccaacagcac cgaccugccc cugaacaucg agugcuucau gaacgacaag      900

gacgugagcg gcaagaugaa ccggucccag uucgaggagc ucugcgccga gcugcugcag      960

aagaucgagg ugccgcucua cagccugcug gagcagacgc accucaaggu cgaggacgug     1020

uccgccgucg agaucguggg cggggccacc cgcauccccg ccgugaagga gcggaucgcg     1080

aaguucuucg gcaaggacau cagcaccacc cugaacgccg acgaggccgu cgcccgcggg     1140

ugcgcccugc agugcgcgau ccucuccccc gccuucaagg ugcgggaguu cagcgugacg     1200

gacgccgucc ccuucccgau cucccugauc uggaaccacg acagcgagga caccgagggc     1260

gugcacgagg uguucucccg caaccacgcc gcgcccuuca gcaagguccu gaccuuccuc     1320

cggcgcgggc ccuucgagcu ggaggccuuc uacuccgacc cccagggcgu gccguacccc     1380

gaggccaaga ucggccgguu cgugguccag aacgugagcg cccagaagga cggggagaag     1440

ucccgcguga aggucaaggu gcgggugaac acccacggca ucuucacgau cagcaccgcc     1500

uccauggucg agaaggugcc caccgaggag aacgagauga gcuccgaggc ggacauggag     1560

ugccugaacc agcggccccc ggagaacccc gacaccgaca agaacgugca gcaggacaac     1620

agcgaggccg ggacgcagcc ccagguccag accgacgccc agcagaccuc ccagagcccg     1680

cccagccccg agcucaccuc cgaggagaac aagauccccg acgccgacaa ggccaacgag     1740

aagaaggugg accagccccc ggaggcgaag aagcccaaga ucaagguggu caacguggag     1800

cugcccaucg aggccaaccu gguguggcag cucggcaagg accugcugaa cauguacauc     1860

gagacggagg ggaagaugau caugcaggac aagcucgaga aggagcgcaa cgacgccaag     1920

aacgccgucg aggaguacgu guacgaguuc cgcgacaagc ugugcggccc guacgagaag     1980

uucaucugcg agcaggacca ccagaacuuc cugcgccugc ucaccgagac cgaggacugg     2040

cuguacgagg agggcgagga ccaggccaag caggcguacg uggacaagcu ggaggagcuc     2100

augaagaucg ggacccccgu caaggugcgg uuccaggagg ccgaggagcg ccccaagaug     2160

uucgaggagc ugggccagcg gcugcagcac uacgccaaga ucgccgcgga cuuccgcaac     2220

aaggacgaga aguacaacca caucgacgag agcgagauga agaaggugga gaaguccguc     2280

aacgagguga uggaguggau gaacaacgug augaacgccc aggccaagaa gucccucgac     2340

caggaccccg ucgugcgggc ccaggagauc aagacgaaga ucaaggagcu gaacaacacg     2400

ugcgagccgg uggucaccca gcccaagccc aagaucgaga gccccaagcu ggagcgcacc     2460

ccgaacgggc ccaacaucga caagaaggag gaggaccucg aggacaagaa caacuucggc     2520

gccgagccgc cccaccagaa cggggagugc uaccccaacg agaagaacag cgugaacaug     2580

gaccuggacu gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  1542
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt1)

<400>  1542
gggagaaagc uuaccauggc cgacaaggug cgccggcagc gcccccggcg ccgggucugc       60

ugggcccugg uggcggugcu ccuggccgac cugcucgccc ugagcgacac ccuggccguc      120

auguccgugg accucggcag cgaguccaug aagguggcca ucgucaagcc gggggugccc      180

auggagaucg ugcugaacaa ggagagccgc cggaagaccc ccgucaucgu gacgcugaag      240

gagaacgagc gcuucuucgg cgacuccgcg gccagcaugg ccaucaagaa ccccaaggcc      300

acccuccggu acuuccagca ccuccugggg aagcaggcgg acaacccgca cguggcccug      360

uaccaggccc gcuuccccga gcacgagcug accuucgacc cccagcggca gaccguccac      420

uuccagaucu ccagccagcu gcaguucucc cccgaggagg ugcucggcau ggugcugaac      480

uacagccgcu cccuggccga ggacuucgcc gagcagccga ucaaggacgc ggucaucacg      540

gugcccgugu ucuucaacca ggccgagcgg cgcgccgucc uccaggccgc ccggauggcg      600

gggcugaagg ugcugcagcu caucaacgac aacaccgcca ccgcccugag cuacggcgug      660

uuccgccgga aggacaucaa caccacggcc cagaacauca uguucuacga caugggcucc      720

gggagcaccg ucugcaccau cgugaccuac cagaugguga agacgaagga ggccggcaug      780

cagccccagc ugcagauccg cggggucggc uucgaccgga cccucggggg ccuggagaug      840

gagcugcgcc uccgggagcg ccuggcgggc cuguucaacg agcagcgcaa ggggcagcgg      900

gccaaggacg ugcgcgagaa cccccgggcc auggccaagc uccugcgcga ggccaaccgg      960

cugaagaccg uccucuccgc gaacgccgac cacauggccc agaucgaggg ccugauggac     1020

gacguggacu ucaaggccaa ggugacccgc gucgaguucg aggagcugug cgcggaccuc     1080

uucgagcggg ugccggggcc cgugcagcag gcccugcaga gcgccgagau gucccuggac     1140

gagaucgagc aggucauccu cgugggcggc gccacgcgcg ugccccgggu ccaggaggug     1200

cugcugaagg ccguggggaa ggaggagcuc ggcaagaaca ucaacgcgga cgaggccgcc     1260

gccauggggg ccgucuacca ggcggccgcc cugagcaagg ccuucaaggu gaagcccuuc     1320

gugguccgcg acgccguggu guacccgauc cuggucgagu ucacccggga gguggaggag     1380

gagcccggca uccacucccu caagcacaac aagcgcgugc uguucagccg gauggggccc     1440

uacccccagc gcaaggucau caccuucaac cgguacagcc acgacuucaa cuuccacauc     1500

aacuacggcg accugggcuu ccucgggccg gaggaccugc gcguguucgg cucccagaac     1560

cugaccacgg ugaagcugaa gggggucggc gacagcuuca agaaguaccc cgacuacgag     1620

uccaagggga ucaaggcgca cuucaaccuc gacgagagcg gcgugcuguc ccuggaccgg     1680

guggagagcg ucuucgagac ccucguggag gacuccgccg aggaggagag cacccugacc     1740

aagcugggca acacgaucuc cagccucuuc gggggcggga ccacccccga cgccaaggag     1800

aacggcaccg acacggugca ggaggaggag gagucccccg ccgaggggag caaggacgag     1860

ccgggcgagc aggucgagcu gaaggaggag gcggaggccc ccguggagga cggcucccag     1920

ccgccgccgc ccgagcccaa gggggacgcc acccccgagg gcgagaaggc caccgagaag     1980

gagaacgggg acaagagcga ggcccagaag cccuccgaga aggcggaggc cggccccgag     2040

ggcguggccc ccgcccccga gggggagaag aagcagaagc ccgcccgcaa gcggcgcaug     2100

gucgaggaga ucggcgugga gcuggugguc cucgaccugc ccgaccugcc cgaggacaag     2160

cucgcgcaga gcgugcagaa gcugcaggac cugacccucc gcgaccugga gaagcaggag     2220

cgggagaagg ccgccaacuc ccuggaggcc uucaucuucg agacgcagga caagcucuac     2280

cagccggagu accaggaggu gagcaccgag gagcagcgcg aggagaucuc cgggaagcug     2340

agcgccgcga gcaccuggcu ggaggacgag ggcgucgggg ccaccacggu gaugcucaag     2400

gagaagcugg ccgagcugcg gaagcucugc cagggccugu ucuuccgcgu ggaggagcgg     2460

aagaaguggc ccgagcgccu guccgcccuc gacaaccugc ugaaccacag cuccauguuc     2520

cucaagggcg cgcggcugau ccccgagaug gaccagaucu ucaccgaggu cgagaugacc     2580

acccuggaga aggugaucaa cgagaccugg gccuggaaga acgccacgcu cgccgagcag     2640

gccaagcugc ccgcgaccga gaagccggug cugcucagca aggacaucga ggccaagaug     2700

auggcccugg accgcgaggu ccaguaccug cucaacaagg ccaaguucac caagccccgg     2760

ccccgcccca aggacaagaa cgggacccgg gccgagccgc cccugaacgc guccgccagc     2820

gaccagggcg agaaggugau cccgcccgcc gggcagacgg aggacgccga gcccaucucc     2880

gagcccgaga agguggagac cggcagcgag cccggggaca ccgagccccu ggagcucggc     2940

ggcccggggg ccgagcccga gcagaaggag caguccaccg gccagaagcg cccccugaag     3000

aacgacgagc ugugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1543
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt1)

<400>  1543
gggagaaagc uuaccaugcc cgaggagacc cagacccagg accagcccau ggaggaggag       60

gagguggaga cguucgccuu ccaggccgag aucgcgcagc ugaugagccu caucaucaac      120

accuucuacu ccaacaagga gaucuuccug cgcgagcuga ucagcaacuc cagcgacgcc      180

cucgacaaga uccgguacga gucccugacc gaccccagca agcuggacuc cggcaaggag      240

cuccacauca accugauccc caacaagcag gaccgcaccc ugacgaucgu cgacaccggg      300

aucggcauga ccaaggccga ccucaucaac aaccugggga ccaucgccaa gagcggcacg      360

aaggccuuca uggaggcgcu gcaggccggg gccgacaucu ccaugaucgg ccaguucggc      420

gugggguucu acagcgccua ccucguggcg gagaagguca ccgugaucac caagcacaac      480

gacgacgagc aguacgccug ggaguccagc gccggcgggu ccuucaccgu gcggacggac      540

accggcgagc ccauggggcg cggcaccaag gucauccugc accugaagga ggaccagacc      600

gaguaccucg aggagcggcg caucaaggag aucgugaaga agcacagcca guucaucggc      660

uacccgauca cgcuguucgu ggagaaggag cgggacaagg aggucuccga cgacgaggcc      720

gaggagaagg aggacaagga ggaggagaag gagaaggagg agaaggagag cgaggacaag      780

cccgagaucg aggacguggg guccgacgag gaggaggaga agaaggacgg cgacaagaag      840

aagaagaaga agaucaagga gaaguacauc gaccaggagg agcugaacaa gaccaagccc      900

aucuggaccc gcaaccccga cgacaucacc aacgaggagu acggggaguu cuacaagagc      960

cucacgaacg acugggagga ccaccuggcc gugaagcacu ucuccgucga gggccagcug     1020

gaguuccggg cgcuccuguu cgugccgcgc cgggcccccu ucgaccuguu cgagaaccgc     1080

aagaagaaga acaacaucaa gcucuacgug cggcgcgucu ucaucaugga caacugcgag     1140

gagcugaucc ccgaguaccu gaacuucauc cggggcgugg uggacagcga ggaccucccc     1200

cugaacauca gccgcgagau gcugcagcag uccaagaucc ucaaggucau ccggaagaac     1260

cuggugaaga agugccugga gcuguucacc gagcucgccg aggacaagga gaacuacaag     1320

aaguucuacg agcaguucag caagaacauc aagcugggga uccacgagga cucccagaac     1380

cgcaagaagc ucagcgagcu gcugcgguac uacaccuccg ccagcggcga cgagauggug     1440

ucccucaagg acuacugcac ccgcaugaag gagaaccaga agcacaucua cuacaucacg     1500

ggggagacca aggaccaggu cgccaacagc gcguucgugg agcggcugcg caagcacggc     1560

cuggagguga ucuacaugau cgagccgauc gacgaguacu gcguccagca gcucaaggag     1620

uucgagggga agacccuggu guccgucacc aaggagggcc uggagcuccc cgaggacgag     1680

gaggagaaga agaagcagga ggagaagaag acgaaguucg agaaccugug caagaucaug     1740

aaggacaucc uggagaagaa gguggagaag guggucguga gcaaccgccu cgugaccucc     1800

cccugcugca ucgucaccag caccuacggc uggacggcca acauggagcg gaucaugaag     1860

gcccaggccc ugcgcgacaa cuccaccaug ggguacaugg ccgcgaagaa gcaccuggag     1920

aucaaccccg accacagcau caucgagacc cugcggcaga aggccgaggc cgacaagaac     1980

gacaaguccg ugaaggaccu cgugauccug cuguacgaga ccgcccuccu gagcuccggc     2040

uucagccugg aggacccgca gacgcacgcc aaccgcaucu accggaugau caagcucggg     2100

cugggcaucg acgaggacga ccccaccgcg gacgacaccu ccgccgccgu caccgaggag     2160

augccgcccc uggaggggga cgacgacacc agccgcaugg aggaggugga cugaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  1544
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt1)

<400>  1544
gggagaaagc uuaccaugga cagcuccaag cuggacagcg gcaaggggcu ccacaucaac       60

cuggugccca acaagcagaa ccagacccug accaucgucg acacgcgcau cggcaugacc      120

aagaccgacc ucaucaacaa ccuggggacc gugacgaagu ccggcaccaa ggccuucaug      180

gaggcccugc aggcggacgc cgacaucagc augaucgggc acuucggcgu gggcuucuac      240

uccgccuacc ucgucgccaa gaaggugacc gugaucagca agcacaacaa cgacgagcag      300

uacaccuggg aguccagcgc cgggggcucc uucacggucc ggaccgacga gugaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  1545
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt1)

<400>  1545
gggagaaagc uuaccaugcc cgaggaggug caccacggcg aggaggaggu cgagaccuuc       60

gccuuccagg ccgagaucgc gcagcugaug agccucauca ucaacaccuu cuacuccaac      120

aaggagaucu uccugcgcga gcugaucagc aacgccuccg acgcccucga caagauccgg      180

uacgagagcc ugacggaccc guccaagcug gacagcggga aggagcucaa gaucgacauc      240

auccccaacc cccaggagcg cacccugacc cugguggaca ccggcaucgg gaugacgaag      300

gccgaccuca ucaacaaccu gggcaccauc gccaaguccg ggaccaaggc guucauggag      360

gcccugcagg ccggcgccga caucagcaug aucggccagu ucgggguggg cuucuacucc      420

gcguaccucg ucgccgagaa gguggugguc aucaccaagc acaacgacga cgagcaguac      480

gccugggaga gcuccgccgg gggcagcuuc acggugcggg ccgaccacgg ggagcccauc      540

ggccgcggca ccaaggugau ccugcaccug aaggaggacc agaccgagua ccucgaggag      600

cggcgcguca aggagguggu gaagaagcac ucccaguuca ucggguaccc gaucacccug      660

uaccuggaga aggagcggga gaaggagauc agcgacgacg aggcggagga ggagaagggc      720

gagaaggagg aggaggacaa ggacgacgag gagaagccca agaucgagga cgucgggucc      780

gacgaggagg acgacagcgg caaggacaag aagaagaaga cgaagaagau caaggagaag      840

uacaucgacc aggaggagcu caacaagacc aagcccaucu ggacccgcaa ccccgacgac      900

aucacccagg aggaguacgg cgaguucuac aagucccuga cgaacgacug ggaggaccac      960

cuggccguga agcacuucag cguggagggg cagcucgagu uccgggcccu gcuguucauc     1020

ccgcgccggg cccccuucga ccucuucgag aacaagaaga agaagaacaa caucaagcug     1080

uacguccgcc ggguguucau cauggacucc ugcgacgagc ugauccccga guaccucaac     1140

uucauccgcg gcguggucga cagcgaggac cugccccuga acaucagccg ggagaugcuc     1200

cagcagucca agauccugaa ggugauccgc aagaacaucg ugaagaagug ccuggagcug     1260

uucagcgagc ucgccgagga caaggagaac uacaagaagu ucuacgaggc guucuccaag     1320

aaccugaagc ucgggaucca cgaggacagc accaaccggc gccggcuguc cgagcugcuc     1380

cgcuaccaca ccagccaguc cggcgacgag augaccagcc uguccgagua cgucagccgg     1440

augaaggaga cgcagaaguc caucuacuac aucaccgggg agagcaagga gcaggucgcc     1500

aacuccgccu ucguggagcg cgugcgcaag cggggcuucg agguggucua caugaccgag     1560

ccgaucgacg aguacugcgu gcagcagcug aaggaguucg acggcaagag ccucgugucc     1620

gucaccaagg aggggcugga gcugcccgag gacgaggagg agaagaagaa gauggaggag     1680

agcaaggcca aguucgagaa ccucugcaag cugaugaagg agauccugga caagaaggug     1740

gagaagguga cgaucuccaa ccgccucguc agcucccccu gcugcaucgu gaccagcacc     1800

uacggcugga ccgccaacau ggagcggauc augaaggcgc aggcccugcg cgacaacagc     1860

acgauggggu acaugauggc caagaagcac cuggagauca accccgacca cccgaucgug     1920

gagacccugc ggcagaaggc cgaggccgac aagaacgaca aggcggucaa ggaccucgug     1980

gugcugcugu ucgagaccgc ccuccugucc agcggcuucu cccuggagga cccccagacc     2040

cacagcaacc gcaucuaccg gaugaucaag cucgggcugg gcaucgacga ggacgagguc     2100

gccgccgagg agcccaacgc ggccgugccc gacgagaucc cgccccugga gggcgacgag     2160

gacgccuccc gcauggagga gguggacuga ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  1546
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt1)

<400>  1546
gggagaaagc uuaccaugcg cgcccugugg gugcucggcc ugugcugcgu ccugcucacc       60

uucgggagcg ugcgggccga cgacgaggug gacgucgacg gcaccgugga ggaggaccug      120

gggaaguccc gcgagggcag ccggacggac gacgaggugg uccagcgcga ggaggaggcg      180

auccagcugg acgggcucaa cgccucccag auccgggagc ugcgcgagaa guccgagaag      240

uucgccuucc aggccgaggu gaaccggaug augaagcuga ucaucaacag ccucuacaag      300

aacaaggaga ucuuccugcg cgagcugauc agcaacgccu ccgacgcgcu cgacaagauc      360

cggcugauca gccugaccga cgagaacgcc cucuccggca acgaggagcu gaccgugaag      420

aucaagugcg acaaggagaa gaaccugcuc cacgucaccg acacgggcgu ggggaugacc      480

cgcgaggagc uggugaagaa ccugggcacc aucgccaaga gcgggaccuc cgaguuccuc      540

aacaagauga cggaggccca ggaggacggc cagagcaccu ccgagcugau cgggcaguuc      600

ggcgucggcu ucuacagcgc guuccuggug gccgacaagg ugaucgucac cuccaagcac      660

aacaacgaca cccagcacau cugggagagc gacuccaacg aguucagcgu gaucgccgac      720

ccccggggga acacgcucgg ccgcgggacc accaucaccc uggugcugaa ggaggaggcc      780

uccgacuacc ucgagcugga cacgaucaag aaccugguca agaaguacag ccaguucauc      840

aacuucccga ucuacgugug gagcuccaag accgagaccg uggaggagcc cauggaggag      900

gaggaggccg cgaaggagga gaaggaggag agcgacgacg aggccgccgu cgaggaggag      960

gaggaggaga agaagcccaa gaccaagaag guggagaaga cgguguggga cugggagcuc     1020

augaacgaca ucaagcccau cuggcagcgg ccguccaagg aggucgagga ggacgaguac     1080

aaggccuucu acaagagcuu cuccaaggag agcgacgacc ccauggccua cauccacuuc     1140

accgcggagg gcgaggugac cuucaagucc auccuguucg uccccaccag cgcgccccgc     1200

ggccuguucg acgaguacgg guccaagaag uccgacuaca ucaagcucua cgugcggcgc     1260

guguucauca cggacgacuu ccacgacaug augccgaagu accugaacuu cgucaagggc     1320

gugguggaca gcgacgaccu gccccucaac gucagccggg agacccugca gcagcacaag     1380

cugcucaagg ugauccgcaa gaagcuggug cggaagaccc uggacaugau caagaagauc     1440

gccgacgaca aguacaacga caccuucugg aaggaguucg ggacgaacau caagcucggc     1500

gucaucgagg accacuccaa ccgcacccgg cuggccaagc ugcuccgcuu ccagagcucc     1560

caccacccca ccgacaucac cagccuggac caguacgugg agcgcaugaa ggagaagcag     1620

gacaagaucu acuucauggc cggguccagc cggaaggagg ccgaguccag ccccuucgug     1680

gagcgccugc ucaagaaggg cuacgagguc aucuaccuga cggagccggu ggacgaguac     1740

ugcauccagg cccugcccga guucgacggc aagcgguucc agaacguggc caaggagggg     1800

gucaaguucg acgagagcga gaagaccaag gagucccgcg aggccgugga gaaggaguuc     1860

gagccccugc ucaacuggau gaaggacaag gcccugaagg acaagaucga gaaggcggug     1920

gucagccagc ggcugaccga gucccccugc gcccucgugg ccagccagua cggcuggucc     1980

gggaacaugg agcgcaucau gaaggcccag gcguaccaga ccggcaagga caucagcacg     2040

aacuacuacg ccucccagaa gaagaccuuc gagaucaacc cgcggcaccc ccugauccgc     2100

gacaugcugc ggcgcaucaa ggaggacgag gacgacaaga ccgugcucga ccuggccguc     2160

gugcuguucg agaccgccac ccuccggagc ggguaccugc ugcccgacac gaaggccuac     2220

ggcgaccgca ucgagcggau gcuccgccug ucccugaaca ucgaccccga cgcgaaggug     2280

gaggaggagc cggaggagga gcccgaggag accgccgagg acaccaccga ggacacggag     2340

caggacgagg acgaggagau ggacgucggc accgacgagg aggaggagac cgccaaggag     2400

agcaccgccg agaaggacga gcucugagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  1547
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt1)

<400>  1547
gggagaaagc uuaccauggc ccgcgagcug cgggcccucc ugcugugggg ccgccggcuc       60

cgcccccugc ugcgggcgcc ggcccucgcc gccgugcccg ggggcaagcc cauccugugc      120

ccccgccgga ccaccgccca gcuggggccg cgccggaacc ccgcguggag ccuccaggcc      180

ggccgccugu ucuccacgca gaccgccgag gacaaggagg agccccugca cagcaucauc      240

uccagcaccg aguccgucca ggggagcacc uccaagcacg aguuccaggc cgagacgaag      300

aagcuccugg acaucguggc gcggagccug uacuccgaga aggagguguu cauccgcgag      360

cucaucagca acgccuccga cgcccuggag aagcugcggc acaagcucgu cagcgacggc      420

caggcccugc ccgagaugga gauccaccuc cagaccaacg ccgagaaggg caccaucacc      480

auccaggaca cggggaucgg caugacccag gaggagcugg uguccaaccu ggggaccauc      540

gcgcgcagcg gcuccaaggc cuuccuggac gcccuccaga accaggccga ggccagcucc      600

aagaucaucg ggcaguucgg cgugggcuuc uacagcgcgu ucauggucgc cgaccgggug      660

gagguguacu cccgcagcgc cgccccgggg agccugggcu accaguggcu guccgacggg      720

agcggcgucu ucgagaucgc cgaggcgucc ggcgugcgga ccgggacgaa gaucaucauc      780

caccucaaga gcgacugcaa ggaguucucc agcgaggccc gcgugcggga cgucgugacc      840

aaguacucca acuucgugag cuucccccug uaccugaacg gccgccggau gaacacccuc      900

caggccaucu ggaugaugga ccccaaggac guccgcgagu ggcagcacga ggaguucuac      960

cgcuacgugg cccaggccca cgacaagccc cgguacaccc ugcacuacaa gacggacgcg     1020

ccgcugaaca uccgcuccau cuucuacgug cccgacauga agcccagcau guucgacguc     1080

ucccgggagc ucgggagcuc cguggcccug uacagccgca aggugcugau ccagaccaag     1140

gccaccgaca uccuccccaa guggcugcgg uucauccgcg gcgucgugga cuccgaggac     1200

aucccgcuga accucagccg ggagcugcug caggaguccg cccucauccg caagcugcgg     1260

gacgugcugc agcagcgccu caucaaguuc uucaucgacc agagcaagaa ggacgcggag     1320

aaguacgcca aguucuucga ggacuacggg cuguucaugc gggagggcau cgucaccgcc     1380

acggagcagg aggugaagga ggacaucgcc aagcugcucc gcuacgaguc cagcgcccug     1440

cccagcggcc agcugaccuc ccugagcgag uacgcguccc ggaugcgcgc cgggacccgg     1500

aacaucuacu accucugcgc ccccaaccgc caccuggccg agcacagccc cuacuacgag     1560

gccaugaaga agaaggacac cgagguccug uucugcuucg agcaguucga cgagcucacg     1620

cugcugcacc uccgggaguu cgacaagaag aagcugaucu ccguggagac cgacaucgug     1680

gucgaccacu acaaggagga gaaguucgag gaccgcagcc cggcggccga gugccugucc     1740

gagaaggaga ccgaggagcu cauggccugg augcggaacg ugcugggcag ccgcgugacc     1800

aacgucaagg ugacgcugcg ccucgacacc caccccgcca uggugaccgu ccuggagaug     1860

ggggccgcgc ggcacuuccu gcgcaugcag cagcucgcca agacccagga ggagcgggcc     1920

cagcugcugc agcccacgcu cgagaucaac ccccgccacg cccugaucaa gaagcugaac     1980

cagcuccggg cguccgagcc gggccuggcc cagcugcucg uggaccagau cuacgagaac     2040

gccaugaucg ccgccgggcu gguggacgac ccccgcgcga uggucggccg gcugaacgag     2100

cuccugguga aggcccugga gcgccacuga ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  1548
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt1)

<400>  1548
gggagaaagc uuaccauggg caagaucagc ucccugccca cccagcuguu caagugcugc       60

uucugcgacu uccucaaggu gaagaugcac accaugagcu ccagccaccu guucuaccuc      120

gcccugugcc ugcucacguu caccuccagc gccaccgcgg ggccggagac ccugugcggc      180

gccgagcugg ucgacgcccu ccaguucgug ugcggggacc gcggcuucua cuucaacaag      240

cccacggggu acggcuccag cucccggcgc gcgccccaga ccggcaucgu ggacgagugc      300

ugcuuccgga gcugcgaccu gcgccggcug gagauguacu gcgcgccccu caagccggcc      360

aaguccgccc gcagcguccg ggcccagcgc cacaccgaca ugcccaagac ccagaaggag      420

gugcaccuga agaacgccuc ccgggggagc gccggcaaca agaacuaccg caugugagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  1549
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt1)

<400>  1549
gggagaaagc uuaccauggg cauccccaug gggaagucca ugcuggugcu ccugaccuuc       60

cuggccuucg ccagcugcug caucgcggcc uaccgcccga gcgagacccu cugcggcggg      120

gagcuggucg acacgcugca guucgugugc ggcgaccggg gguucuacuu cucccgcccc      180

gccagccggg ugucccgccg gagccgcggc aucgucgagg agugcugcuu ccgguccugc      240

gaccucgccc ugcuggagac cuacugcgcc acccccgcca agagcgagcg cgacgugucc      300

acgcccccga ccgugcuccc cgacaacuuc ccccgguacc ccgucggcaa guucuuccag      360

uacgacaccu ggaagcagag cacccagcgc cugcggcgcg ggcugccggc gcuccugcgg      420

gcccgccggg gccacgugcu ggccaaggag cucgaggcgu uccgcgaggc caagcggcac      480

cgcccccuga ucgcccugcc cacccaggac cccgcccacg ggggcgcccc gcccgagaug      540

gcguccaacc ggaagugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  1550
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt1)

<400>  1550
gggagaaagc uuaccaugaa cagcuucucc accagcgccu ucggccccgu ggccuucucc       60

cuggggcucc ugcugguccu cccggcggcc uuccccgccc ccgugccccc gggcgaggac      120

agcaaggacg uggccgcgcc ccaccgccag ccccugaccu ccagcgagcg gaucgacaag      180

cagauccgcu acauccugga cgggaucucc gcccuccgga aggagacgug caacaagagc      240

aacaugugcg aguccagcaa ggaggcccug gccgagaaca accugaaccu ccccaagaug      300

gccgagaagg acggcugcuu ccaguccggg uucaacgagg agaccugccu ggucaagauc      360

aucaccggcc ugcucgaguu cgagguguac cuggaguacc ugcagaaccg cuucgagagc      420

uccgaggagc aggcgcgggc cgugcagaug agcaccaagg uccucaucca guuccugcag      480

aagaaggcca agaaccugga cgccaucacg accccggacc ccaccaccaa cgccucccuc      540

cugacgaagc ugcaggcgca gaaccagugg cuccaggaca ugaccaccca ccugauccug      600

cgcagcuuca aggaguuccu ccaguccagc cugcgggccc ugcgccagau gugaggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  1551
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt1)

<400>  1551
gggagaaagc uuaccaugcc ccugcucugg cugcgcggcu uccugcucgc cagcugcugg       60

aucaucgugc gguccagccc gacccccggg uccgagggcc acagcgccgc gcccgacugc      120

cccuccugcg cccuggccgc ccugccgaag gacgucccca acagccagcc cgagauggug      180

gaggccguga agaagcacau ccucaacaug cugcaccuga agaagcgccc cgacgucacc      240

cagccggugc ccaaggcggc ccuccugaac gccauccgga agcugcacgu ggggaagguc      300

ggcgagaacg gguacgugga gaucgaggac gacaucggcc gccgggccga gaugaacgag      360

cucauggagc agacguccga gaucaucacc uucgcggaga gcggcaccgc ccgcaagacc      420

cugcacuucg agaucuccaa ggaggggagc gaccuguccg uggucgagcg ggccgaggug      480

uggcuguucc ucaaggugcc caaggccaac cgcacgcgga ccaaggucac cauccgccug      540

uuccagcagc agaagcaccc ccagggcagc cucgacaccg gggaggaggc cgaggaggug      600

ggccugaagg gggagcgguc cgagcugcuc cugagcgaga agguggucga cgcgcgcaag      660

uccacguggc acguguuccc ggugagcucc agcauccagc ggcugcucga ccagggcaag      720

uccagccugg acguccgcau cgccugcgag cagugccagg agagcggcgc cucccuggug      780

cuccugggga agaagaagaa gaaggaggag gagggcgagg ggaagaagaa gggcggcggg      840

gagggcgggg ccggcgccga cgaggagaag gagcagagcc accggcccuu ccugaugcuc      900

caggcgcgcc aguccgagga ccacccccac cggcgccggc gccgggggcu ggagugcgac      960

ggcaagguga acaucugcug caagaagcag uucuucguca gcuucaagga caucggcugg     1020

aacgacugga ucaucgcccc cuccggguac cacgccaacu acugcgaggg cgagugcccg     1080

agccacaucg ccgggaccuc cggcagcucc cugagcuucc acuccaccgu gaucaaccac     1140

uaccgcaugc gcgggcacag ccccuucgcc aaccucaagu ccugcugcgu gcccaccaag     1200

cugcggccca ugagcaugcu guacuacgac gacggccaga acaucaucaa gaaggacauc     1260

cagaacauga ucgucgagga gugcggcugc uccugaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  1552
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt1)

<400>  1552
gggagaaagc uuaccaugga cggccugccc gggcgcgccc ucggcgccgc gugccugcug       60

cuccuggccg ccggguggcu gggcccggag gccuggggga gccccacccc gcccccgacc      120

cccgccgcgc ccccgccccc gcccccgccc ggcucccccg gcgggagcca ggacacgugc      180

accuccugcg gcggguuccg gcgccccgag gagcucggcc ggguggacgg ggacuuccug      240

gaggccguca agcgccacau ccugagccgg cuccagaugc gcggccggcc caacaucacc      300

cacgccgugc ccaaggccgc gauggugacc gcccugcgca agcugcacgc cggcaagguc      360

cgggaggacg ggcgcgugga gaucccccac cucgacggcc acgccucccc cggggccgac      420

ggccaggagc gggugagcga gaucaucucc uucgcggaga cggacggccu ggccagcucc      480

cgcguccggc uguacuucuu caucagcaac gaggggaacc agaaccucuu cguggugcag      540

gccucccugu ggcuguaccu caagcugcug cccuacgucc ucgagaaggg cagccgccgg      600

aaggugcgcg ugaaggucua cuuccaggag caggggcacg gcgaccggug gaacauggug      660

gagaagcgcg uggaccugaa gcgguccggg uggcacaccu ucccccugac cgaggccauc      720

caggcccucu ucgagcgcgg cgagcggcgc cugaaccugg acguccagug cgacagcugc      780

caggagcucg cgguggugcc cgucuucgug gaccccggcg aggaguccca ccgccccuuc      840

guggucgugc aggcccggcu gggggacagc cgccaccgga uccgcaagcg gggccuggag      900

ugcgacgggc gcaccaaccu cugcugccgg cagcaguucu ucaucgacuu ccgccugauc      960

ggcuggaacg acuggaucau cgccccgacg ggguacuacg gcaacuacug cgagggcucc     1020

ugccccgccu accuggccgg ggugcccggc agcgcgucca gcuuccacac cgccgucgug     1080

aaccaguacc ggaugcgcgg gcucaacccc ggcaccguca acagcugcug caucccgacc     1140

aagcugucca cgaugagcau gcuguacuuc gacgacgagu acaacaucgu gaagcgggac     1200

gugcccaaca ugaucgucga ggagugcggg ugcgccugag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  1553
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt1)

<400>  1553
gggagaaagc uuaccauggc ccugcgcgug cuccugcuga ccgcccucac ccugugccac       60

ggcuucaacc uggacacgga gaacgcgaug accuuccagg agaacgcccg gggguucggc      120

cagagcgucg ugcagcucca ggggucccgc guggucgugg gcgcccccca ggagaucgug      180

gccgccaacc agcgggggag ccuguaccag ugcgacuacu ccaccggcag cugcgagccg      240

auccgccugc agguccccgu ggaggcggug aacauguccc ucggccugag ccuggccgcc      300

accacguccc ccccccagcu ccuggccugc gggccgaccg uccaccagac cugcagcgag      360

aacaccuacg ugaagggccu gugcuuccuc uucgggucca accugcggca gcagccccag      420

aaguuccccg aggcgcugcg cggcugcccc caggaggaca gcgacaucgc cuuccucauc      480

gacggguccg gcagcaucau cccgcacgac uuccggcgca ugaaggaguu cguguccacg      540

gucauggagc agcugaagaa guccaagacc cuguucuccc ucaugcagua cagcgaggag      600

uuccggaucc acuucaccuu caaggaguuc cagaacaacc ccaacccccg cucccuggug      660

aagcccauca cccagcugcu cggccggacg cacaccgcca ccgggauccg caaggugguc      720

cgggagcugu ucaacaucac caacggcgcc cgcaagaacg ccuucaagau ccugguggug      780

aucacggacg gggagaaguu cggcgacccg cucggcuacg aggacgucau ccccgaggcg      840

gaccgggagg gggugauccg cuacgugauc ggcgucgggg acgccuuccg gagcgagaag      900

ucccgccagg agcugaacac caucgccagc aagccccccc gggaccacgu guuccaggug      960

aacaacuucg aggcccugaa gaccauccag aaccagcucc gcgagaagau cuucgccauc     1020

gagggcaccc agacggggag cuccagcucc uucgagcacg agaugagcca ggagggcuuc     1080

uccgcggcca ucaccagcaa cggcccgcug cuguccaccg ucgggagcua cgacugggcc     1140

ggcggggugu uccucuacac cuccaaggag aaguccacgu ucaucaacau gacccggguc     1200

gacuccgaca ugaacgacgc cuaccugggc uacgccgcgg ccaucauccu gcgcaaccgc     1260

gugcagagcc ucgugcuggg ggccccccgg uaccagcaca ucggccuggu cgccauguuc     1320

cgccagaaca ccggcaugug ggaguccaac gccaacguga aggggaccca gaucggcgcg     1380

uacuucgggg ccagccucug cuccguggac gucgacagca acggcuccac ggaccuggug     1440

cugaucgggg ccccccacua cuacgagcag acccggggcg gccaggugag cgucugcccc     1500

cucccgcgcg ggcgggcccg cuggcagugc gacgcggugc uguacggcga gcaggggcag     1560

cccuggggcc gguucggcgc cgcccugacc gugcucgggg acgucaacgg cgacaagcug     1620

accgacgugg ccaucggggc ccccggcgag gaggacaacc gcggggcggu guaccuguuc     1680

cacggcacgu ccggcagcgg gaucagcccc ucccacagcc agcggaucgc cggcuccaag     1740

cucagcccgc gccugcagua cuucgggcag ucccugagcg gcgggcagga ccugaccaug     1800

gacggccucg ucgaccugac cgugggcgcc caggggcacg ugcugcuccu gcggucccag     1860

cccguccugc gcgugaaggc caucauggag uucaaccccc gggagguggc ccgcaacguc     1920

uucgagugca acgaccaggu ggugaagggc aaggaggcgg gggagguccg ggugugccuc     1980

cacgugcaga aguccacccg cgaccggcug cgcgagggcc agauccaguc cgucgugacg     2040

uacgaccugg cccucgacag cgggcggccc cacucccgcg ccguguucaa cgagaccaag     2100

aacagcaccc gccggcagac ccagguccug ggccugaccc agacgugcga gacccucaag     2160

cugcagcugc cgaacugcau cgaggacccc guguccccca ucgugcuccg ccugaacuuc     2220

agccuggucg gcaccccgcu cuccgccuuc gggaaccugc ggcccgugcu ggccgaggac     2280

gcgcagcgcc ucuucaccgc ccuguucccc uucgagaaga acugcggcaa cgacaacauc     2340

ugccaggacg accugagcau cacguucucc uucaugagcc ucgacugccu gguggucggg     2400

ggcccccggg aguucaacgu gaccgugacc guccgcaacg acggggagga cagcuaccgg     2460

acccagguga cguucuucuu cccgcuggac cucuccuacc gcaaggugag cacccugcag     2520

aaccagcggu cccagcgcag cuggcggcug gccugcgagu ccgccagcuc caccgagguc     2580

agcggcgcgc ucaaguccac cagcugcucc aucaaccacc ccaucuuccc cgagaacagc     2640

gaggugacgu ucaacaucac cuucgacgug gacuccaagg ccagccuggg caacaagcug     2700

cuccugaagg ccaacgucac cuccgagaac aacaugcccc gcaccaacaa gacggaguuc     2760

cagcuggagc ucccggugaa guacgccgug uacauggucg ugaccagcca cggggugucc     2820

accaaguacc ugaacuucac cgccagcgag aacacguccc gggucaugca gcaccaguac     2880

caggugagca accugggcca gcgcagccuc cccaucuccc uggucuuccu ggugcccgug     2940

cggcucaacc agaccgucau cugggaccgc ccccagguga ccuucagcga gaaccugucc     3000

agcacaugcc acacgaagga gcggcugccg ucccacagcg acuuccucgc ggagcugcgc     3060

aaggcccccg uggucaacug cuccaucgcc gugugccagc ggauccagug cgacaucccc     3120

uucuucggga uccaggagga guucaacgcc acccugaagg gcaaccucag cuucgacugg     3180

uacaucaaga ccucccacaa ccaccuccug aucgugagca ccgccgagau ccucuucaac     3240

gacuccgucu ucacgcugcu gcccggccag ggggcguucg ugcgcagcca gaccgagacc     3300

aagguggagc cguucgaggu ccccaacccc cucccccuga ucgugggcuc cagcgugggg     3360

ggccugcucc ugcuggcccu caucaccgcc gcccuguaca agcugggguu cuucaagcgg     3420

caguacaagg acaugauguc cgagggcggc ccgcccgggg ccgagcccca gugaggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  1554
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt1)

<400>  1554
gggagaaagc uuaccauguu cagccugaag acccuccccu uccugcugcu ccugcacgug       60

cagaucucca aggccuuccc ggucagcucc aaggagaaga acaccaagac ggugcaggac      120

uaccuggaga aguucuacca gcuccccagc aaccaguacc aguccacccg caagaacggc      180

accaacguga ucgucgagaa gcugaaggag augcagcggu ucuucgggcu gaacgugacc      240

ggcaagccca acgaggagac gcucgacaug augaagaagc cccgcugcgg ggugccggac      300

agcggcgggu ucaugcugac ccccggcaac cccaaguggg agcggaccaa ccugaccuac      360

cgcauccgga acuacacgcc ccagcucucc gaggccgagg ucgagcgcgc gaucaaggac      420

gccuucgagc uguggagcgu ggccuccccg cugaucuuca cccggaucag ccagggcgag      480

gccgacauca acaucgccuu cuaccagcgc gaccacgggg acaacucccc cuucgacggc      540

cccaacggga uccucgcgca cgccuuccag cccggccagg ggaucggcgg cgacgcccac      600

uucgacgccg aggagaccug gaccaacacg agcgcgaacu acaaccuguu ccugguggcc      660

gcccacgagu ucgggcacuc ccucggccug gcccacagcu ccgacccggg ggcccugaug      720

uaccccaacu acgcguuccg ggagaccagc aacuacuccc ucccccagga cgacaucgac      780

ggcauccagg ccaucuacgg ccugagcucc aaccccaucc agccgaccgg gcccagcacc      840

cccaagcccu gcgacccgag ccugacguuc gacgccauca ccacccuccg cggcgagauc      900

cuguucuuca aggaccggua cuucuggcgc cggcaccccc agcugcagcg cgucgagaug      960

aacuucaucu cccucuucug gcccagccug cccaccggga uccaggccgc cuacgaggac     1020

uucgaccggg accugaucuu ccucuucaag ggcaaccagu acugggcgcu guccggguac     1080

gacauccugc agggcuaccc gaaggacauc agcaacuacg gcuuccccuc cagcgugcag     1140

gccaucgacg ccgccguguu cuaccgcucc aagacguacu ucuucgucaa cgaccaguuc     1200

uggcgguacg acaaccagcg ccaguucaug gagcccgggu accccaagag caucuccggc     1260

gccuucccgg ggaucgagag caagguggac gcgguguucc agcaggagca cuucuuccac     1320

gucuucuccg gcccccggua cuacgccuuc gaccucaucg cccagcgcgu gacccgggug     1380

gcccgcggga acaaguggcu gaacugccgc uacggcugag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  1555
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt1)

<400>  1555
gggagaaagc uuaccaugag ccuguggcag ccccucgugc ugguccugcu cgugcugggc       60

ugcugcuucg ccgccccgcg ccagcggcag uccacccugg uccucuuccc cggggaccug      120

cgcaccaacc ugacggaccg gcagcucgcg gaggaguacc uguaccgcua cggcuacacc      180

cggguggccg agaugcgcgg ggagagcaag ucccugggcc ccgcccuccu gcugcuccag      240

aagcagcuga gccugcccga gaccggggag cucgacuccg ccacccugaa ggccaugcgg      300

acgccgcgcu gcggcgugcc cgaccugggc cgguuccaga ccuucgaggg ggaccucaag      360

uggcaccacc acaacaucac cuacuggauc cagaacuaca gcgaggaccu gccccgcgcg      420

gugaucgacg acgccuucgc ccgggccuuc gcgcuguggu ccgccgucac gccccucacc      480

uucacccgcg uguacagccg ggacgccgac aucgugaucc aguucggcgu cgccgagcac      540

ggggacggcu acccguucga cgggaaggac ggccugcugg cccacgcguu cccgcccggc      600

cccgggaucc agggcgacgc ccacuucgac gacgacgagc ucuggucccu ggggaagggc      660

gugguggucc ccacccgcuu cggcaacgcc gacggggccg ccugccacuu ccccuucauc      720

uucgagggcc ggagcuacuc cgcgugcacc acggacgggc gcagcgacgg ccugcccugg      780

ugcuccacca ccgccaacua cgacaccgac gaccgguucg gguucugccc cagcgagcgc      840

cucuacacgc aggacggcaa cgccgacggc aagccgugcc aguuccccuu caucuuccag      900

gggcaguccu acagcgccug caccaccgac ggccgguccg acggguaccg cuggugcgcc      960

accacggcga acuacgaccg ggacaagcug uucggcuucu gccccacccg cgccgacagc     1020

accgugaugg gcggcaacuc cgccggcgag cugugcgugu uccccuucac cuuccucggg     1080

aaggaguaca gcacgugcac cagcgagggc cgcggggacg gccggcugug gugcgccacc     1140

accuccaacu ucgacagcga caagaagugg ggguucugcc cggaccaggg cuacucccug     1200

uuccucgucg ccgcgcacga guucggccac gcccuggggc uggaccacag cuccgugccc     1260

gaggcccuca uguaccccau guaccgcuuc acggaggggc ccccgcugca caaggacgac     1320

gugaacggga uccggcaccu guacggcccc cgccccgagc ccgagccgcg gccgcccacc     1380

accaccacgc cccagcccac cgccccgccc accgucugcc ccaccggccc gcccacggug     1440

caccccagcg agcgccccac cgcggggccc accggcccgc ccuccgccgg gcccaccggc     1500

ccgcccaccg ccgggcccag cacggccacc accgugcccc ucucccccgu cgacgacgcc     1560

ugcaacguga acaucuucga cgcgaucgcc gagaucggca accagcugua ccuguucaag     1620

gacggcaagu acuggcgguu cagcgagggg cgcggcuccc ggccccaggg gcccuuccuc     1680

aucgccgaca aguggccggc ccugccccgc aagcuggaca gcguguucga ggagcggcuc     1740

uccaagaagc uguucuucuu cagcggccgc caggucuggg uguacaccgg ggccuccguc     1800

cugggccccc ggcgccugga caagcucggc cugggggcgg acguggccca ggugacgggc     1860

gcccugcgga gcgggcgcgg caagaugcuc cuguucuccg ggcggcgccu guggcgguuc     1920

gacgucaagg cccagauggu ggacccccgc agcgccuccg agguggaccg cauguucccg     1980

ggcguccccc ucgacaccca cgacguguuc caguaccggg agaaggcgua cuucugccag     2040

gaccgcuucu acuggcgggu gagcagccgc uccgagcuga accaggucga ccaggugggc     2100

uacgugaccu acgacauccu gcagugcccc gaggacugag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  1556
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt1)

<400>  1556
gggagaaagc uuaccaugca ccccggcgug cuggccgccu uccucuuccu gagcuggacc       60

cacugccgcg cgcugccgcu ccccuccggg ggcgacgagg acgaccugag cgaggaggac      120

cugcaguucg ccgagcggua ccuccgcucc uacuaccacc ccaccaaccu ggccgggauc      180

cugaaggaga acgccgccag cuccaugacg gagcggcucc gcgagaugca gagcuucuuc      240

ggccuggagg ucaccgggaa gcuggacgac aacacccucg acgugaugaa gaagccccgg      300

ugcggcgugc cggacgucgg cgaguacaac guguuccccc gcacccugaa gugguccaag      360

augaaccuga cguaccggau cgugaacuac acccccgaca ugacccacag cgaggucgag      420

aaggcguuca agaaggccuu caaggugugg uccgacguga cgccccucaa cuucacccgc      480

cugcacgacg ggaucgccga caucaugauc agcuucggca ucaaggagca cggggacuuc      540

uacccguucg acggccccuc cgggcugcuc gcccacgcgu ucccgcccgg ccccaacuac      600

ggcggggacg cccacuucga cgacgacgag accuggacca gcuccagcaa gggcuacaac      660

cuguuccugg ucgccgccca cgaguucggg cacucccucg gccuggacca cagcaaggac      720

cccggcgccc ugauguuccc caucuacacc uacacgggga agucccacuu caugcucccc      780

gacgacgacg ugcagggcau ccagagccug uacgggccgg gcgacgagga ccccaacccc      840

aagcacccca agaccccgga caagugcgac cccucccuga gccucgacgc gaucaccagc      900

cugcgcgggg agaccaugau cuucaaggac cgguucuucu ggcggcugca cccccagcag      960

gucgacgccg agcuguuccu gacgaagucc uucuggcccg agcugccgaa ccgcaucgac     1020

gccgccuacg agcaccccag ccacgaccuc aucuucaucu uccggggccg caaguucugg     1080

gcccugaacg gcuacgacau ccuggagggg uaccccaaga agaucuccga gcucggccug     1140

cccaaggagg ugaagaagau cagcgcggcc gugcacuucg aggacaccgg gaagacccuc     1200

cucuucuccg gcaaccaggu guggcgguac gacgacacca accacaucau ggacaaggac     1260

uacccgcgcc ugaucgagga ggacuucccc gggaucggcg acaaggucga cgccguguac     1320

gagaagaacg gcuacaucua cuucuucaac gggcccaucc aguucgagua cagcaucugg     1380

uccaaccgga ucgugcgcgu caugccggcc aacagcaucc uguggugcug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  1557
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt1)

<400>  1557
gggagaaagc uuaccaugga gacccccaac accacggagg acuacgacac caccaccgag       60

uucgacuacg gcgacgccac gccgugccag aaggugaacg agcgcgccuu cggggcgcag      120

cugcucccgc cccuguacag ccuggucuuc gugaucggcc ucguggggaa cauccugguc      180

gugcuggugc ucguccagua caagcggcug aagaacauga ccuccaucua ccugcucaac      240

cuggccauca gcgaccuccu cuuccuguuc acccugcccu ucuggaucga cuacaagcuc      300

aaggacgacu ggguguucgg cgacgccaug ugcaagaucc uguccggguu cuacuacacc      360

ggccuguaca gcgagaucuu cuucaucauc cuccugacga ucgaccgcua ccuggccauc      420

gugcacgccg ucuucgcgcu ccgggcccgc accgugaccu ucggcgugau caccuccauc      480

aucaucuggg cccuggccau ccuggcgagc augcccgggc ucuacuucuc caagacgcag      540

ugggaguuca cccaccacac gugcagccug cacuuccccc acgagucccu gcgggagugg      600

aagcuguucc aggcccugaa gcugaaccuc uucggccugg uccugccccu ccuggugaug      660

aucaucugcu acaccgggau caucaagauc cugcuccgcc ggcccaacga gaagaagucc      720

aaggccgugc gccugaucuu cgucaucaug aucaucuucu uccuguucug gaccccguac      780

aaccucacca uccugaucag cguguuccag gacuuccugu ucacccacga gugcgagcag      840

agccggcacc ucgaccuggc cgugcagguc accgagguga ucgccuacac gcacugcugc      900

gugaaccccg ucaucuacgc guucgugggc gagcgcuucc ggaaguaccu gcgccagcug      960

uuccaccggc gcguggccgu ccaccucgug aaguggcugc ccuuccucuc cgucgaccgg     1020

cuggagcgcg ugagcuccac cagccccucc accggggagc acgagcugag cgccggcuuc     1080

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  1558
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt1)

<400>  1558
gggagaaagc uuaccaugcg cacccuggcc ugccuccugc ugcucggcug cggguaccug       60

gcccacgugc uggcggagga ggccgagauc ccccgggagg ugaucgagcg ccucgcccgg      120

agccagaucc acuccauccg cgaccugcag cggcugcucg agaucgacag cgugggcucc      180

gaggacagcc uggacaccuc ccugcgcgcc cacggggugc acgccacgaa gcacgucccg      240

gagaagcggc cccuccccau ccgccggaag cgcagcaucg aggaggcggu gcccgccgug      300

ugcaagaccc ggaccgucau cuacgagauc ccgcgcuccc agguggaccc caccagcgcc      360

aacuuccuga ucuggccgcc cugcguggag gucaagcggu gcacgggcug cugcaacacc      420

uccagcguga agugccagcc cucccgcgug caccaccgga gcgucaaggu ggccaaggug      480

gaguacgucc gcaagaagcc caagcugaag gagguccagg ugcggcucga ggagcaccug      540

gagugcgcgu gcgccaccac cucccugaac cccgacuacc gcgaggagga cacggggcgg      600

ccccgcgaga gcggcaagaa gcggaagcgc aagcgccuca agccgaccug aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  1559
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt1)

<400>  1559
gggagaaagc uuaccaugaa ccgcugcugg gcccuguucc ucagccugug cugcuaccug       60

cggcucgugu ccgccgaggg cgaccccauc ccggaggagc uguacgagau gcugagcgac      120

cacuccaucc gcagcuucga cgaccuccag cggcugcugc acggggaccc cggcgaggag      180

gacggggcgg agcucgaccu gaacaugacc cgcucccaca gcggcgggga gcuggagucc      240

cucgcccggg gccgccggag ccugggcucc cugaccaucg ccgagcccgc caugaucgcc      300

gagugcaaga cgcgcaccga ggucuucgag aucagccggc gccucaucga ccggaccaac      360

gcgaacuucc ugguguggcc cccgugcgug gagguccagc gcugcuccgg gugcugcaac      420

aaccggaacg ugcagugccg ccccacccag gugcagcugc ggcccgucca ggugcgcaag      480

aucgagaucg ugcggaagaa gcccaucuuc aagaaggcca cggucacccu cgaggaccac      540

cuggccugca agugcgagac cguggccgcg gcccgcccgg ugacccggag ccccggcggg      600

ucccaggagc agcgcgccaa gacgccccag acccggguca ccauccgcac cgugcgcgug      660

cggcggcccc cgaagggcaa gcaccgcaag uucaagcaca cgcacgacaa gaccgcccug      720

aaggagaccc ucggggccug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  1560
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt1)

<400>  1560
gggagaaagc uuaccaugag ccuguucggc cuccugcugc ucaccuccgc ccuggccggg       60

cagcgccagg gcacccaggc ggagagcaac cuguccagca aguuccaguu cuccagcaac      120

aaggagcaga acggggugca ggacccccag cacgagcgga ucaucacggu cuccaccaac      180

ggcagcaucc acuccccgcg cuucccccac accuaccccc ggaacaccgu gcucgugugg      240

cgccuggucg ccguggagga gaacgugugg auccagcuga cguucgacga gcgguucggg      300

cucgaggacc ccgaggacga caucugcaag uacgacuucg ucgaggugga ggagccgagc      360

gacggcacca uccugggccg cuggugcggg uccggcaccg ugcccgggaa gcagaucagc      420

aagggcaacc agauccggau ccgcuucguc uccgacgagu acuuccccag cgagcccggg      480

uucugcaucc acuacaacau cgugaugccg caguucaccg aggccguguc ccccagcguc      540

cugccgcccu ccgcccuccc ccuggaccug cucaacaacg ccaucacggc guucagcacc      600

cuggaggacc ugauccggua ccucgagccc gagcgcuggc agcuggaccu ggaggaccuc      660

uaccggccca ccuggcagcu gcugggcaag gccuucgugu ucggccgcaa gucccgggug      720

gucgaccuca accugcugac cgaggaggug cgccucuaca gcugcacgcc ccggaacuuc      780

agcgugucca uccgcgagga gcugaagcgg accgacacca ucuucuggcc ggggugccug      840

cucgucaagc gcugcggcgg gaacugcgcc ugcugccugc acaacugcaa cgagugccag      900

ugcgugccca gcaaggugac caagaaguac cacgaggucc ugcagcuccg gcccaagacg      960

ggcgugcgcg gccugcacaa gucccugacc gacguggccc ucgagcacca cgaggagugc     1020

gacugcgucu gccgggggag caccggcggg ugaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  1561
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt1)

<400>  1561
gggagaaagc uuaccaugca ccgccugauc uucguguaca cccucaucug cgccaacuuc       60

ugcagcugcc gggacaccuc cgccacgccc cagagcgcgu ccaucaaggc ccugcgcaac      120

gccaaccugc ggcgcgacga ccucuaccgg cgcgacgaga ccauccaggu caagggcaac      180

ggguacgugc agagcccccg guuccccaac uccuaccccc gcaaccugcu gcucaccugg      240

cggcugcaca gccaggagaa cacccgcauc cagcuggugu ucgacaacca guucggccuc      300

gaggaggccg agaacgacau cugccgguac gacuucgucg agguggagga caucuccgag      360

accagcacca ucauccgcgg gcgguggugc ggccacaagg aggugccccc gcgcaucaag      420

ucccggacca accagaucaa gaucaccuuc aagagcgacg acuacuucgu cgccaagccc      480

ggguucaaga ucuacuacuc ccugcuggag gacuuccagc ccgcggccgc cagcgagacg      540

aacugggagu ccgugaccag cuccaucagc ggcguguccu acaacagccc cuccgucacc      600

gacccgaccc ucaucgccga cgcgcuggac aagaagaucg ccgaguucga cacgguggag      660

gaccugcuca aguacuucaa ccccgagagc uggcaggagg accuggagaa cauguaccug      720

gacaccccgc gcuaccgggg ccgcagcuac cacgaccgga aguccaaggu ggaccucgac      780

cgccugaacg acgacgccaa gcgguacagc ugcacgcccc gcaacuacuc cgucaacauc      840

cgcgaggagc ugaagcucgc caacguggug uucuuccccc ggugccugcu gguccagcgc      900

ugcgggggca acugcgggug cggcaccgug aacuggcgga gcugcacgug caacuccggg      960

aagaccguga agaaguacca cgagguccuc caguucgagc ccggccacau caagcgccgg     1020

ggccgcgcca agaccauggc gcugguggac auccagcugg accaccacga gcggugcgac     1080

ugcaucugca gcucccgccc gccccgguga ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  1562
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt1)

<400>  1562
gggagaaagc uuaccauggu gacccacagc aaguuccccg ccgccggcau gucccgcccg       60

cuggacacca gccuccggcu gaagacguuc uccagcaagu ccgaguacca gcuggucgug      120

aacgcggugc gcaagcucca ggagagcggg uucuacuggu ccgccgucac cggcggggag      180

gccaaccugc ugcucagcgc cgagcccgcc ggcaccuucc ugauccggga cuccagcgac      240

cagcgccacu ucuucacccu guccgugaag acgcagagcg ggaccaagaa ccuccggauc      300

cagugcgagg gcggcuccuu cagccugcag uccgaccccc gcagcaccca gcccgugccg      360

cgguucgacu gcguccugaa gcucgugcac cacuacaugc ccccgcccgg ggcgcccucc      420

uuccccagcc cgcccaccga gcccuccagc gaggugcccg agcagcccag cgcccagccc      480

cugccgggcu ccccgccccg ccgggccuac uacaucuaca gcgggggcga gaagaucccc      540

cugguccucu cccgcccccu gagcuccaac guggccacgc ugcagcaccu cugccggaag      600

accgugaacg ggcaccugga cagcuacgag aaggucaccc agcugcccgg ccccauccgc      660

gaguuccucg accaguacga cgcgccccug ugaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  1563
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt1)

<400>  1563
gggagaaagc uuaccauggu gcccagcgcc ggccagcugg cccucuucgc gcuggggauc       60

guccuggccg ccugccaggc ccucgagaac uccaccagcc cgcuguccgc cgacccgccc      120

guggcggccg ccguggucag ccacuucaac gacugccccg acucccacac ccaguucugc      180

uuccacggca cgugccgcuu ccuggugcag gaggacaagc ccgccugcgu gugccacagc      240

ggguacgucg gcgcgcggug cgagcacgcc gaccuccugg ccgugguggc cgccucccag      300

aagaagcagg cgaucaccgc ccuggucgug gugagcaucg ucgcccucgc cgugcugauc      360

aucacgugcg ugcugaucca cugcugccag guccgcaagc acugcgagug gugccgggcc      420

cucaucugcc gccacgagaa gcccuccgcg cugcugaagg ggcggaccgc cugcugccac      480

agcgagaccg uggugugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  1564
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt1)

<400>  1564
gggagaaagc uuaccaugcc cccgagcggc cugcgccucc ugccccugcu ccugccccug       60

cucuggcugc uggugcucac ccccgggcgg ccggccgccg gccuguccac gugcaagacc      120

aucgacaugg agcuggucaa gcgcaagcgg aucgaggcga uccgcgggca gauccucagc      180

aagcugcggc uggccucccc gcccagccag ggcgaggugc cgcccgggcc ccuccccgag      240

gccgugcugg cccuguacaa cuccacccgc gaccgggucg ccggcgagag cgcggagccc      300

gagcccgagc ccgaggccga cuacuacgcc aaggagguga cccgcgugcu cauggucgag      360

acccacaacg agaucuacga caaguucaag caguccacgc acagcaucua cauguucuuc      420

aacaccuccg agcugcggga ggccgugccc gagcccgugc ugcucagccg cgcggagcug      480

cggcugcucc gccugaagcu gaaggucgag cagcacgugg agcucuacca gaaguacucc      540

aacaacagcu ggcgguaccu guccaaccgc cugcucgccc cgagcgacuc ccccgagugg      600

cugagcuucg acgugaccgg cgucgugcgg caguggcugu cccgcggggg cgagaucgag      660

ggguuccggc ucagcgccca cugcuccugc gacagccgcg acaacacccu ccagguggac      720

aucaacggcu ucacgaccgg gcggcgcggc gaccuggcca ccauccacgg caugaaccgg      780

cccuuccugc ugcugauggc cacgccccuc gagcgcgcgc agcaccucca gagcucccgc      840

caccggcgcg cccuggacac caacuacugc uucagcucca ccgagaagaa cugcugcguc      900

cggcagcugu acaucgacuu ccgcaaggac cuggggugga aguggaucca cgagccgaag      960

ggcuaccacg ccaacuucug ccuggggccc ugccccuaca ucuggagccu cgacacccag     1020

uacuccaagg ugcuggcccu guacaaccag cacaaccccg gcgccagcgc ggccccgugc     1080

ugcgugcccc aggcccucga gccccugccc aucgucuacu acgugggccg gaagccgaag     1140

guggagcagc uguccaacau gaucguccgc agcugcaagu gcuccugagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  1565
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt1)

<400>  1565
gggagaaagc uuaccaugca cuacugcgug cugagcgccu uccucauccu gcaccugguc       60

accguggccc ucucccugag cacgugcucc acccuggaca uggaccaguu caugcgcaag      120

cggaucgagg cgauccgcgg ccagauccuc agcaagcuga agcugaccag cccgcccgag      180

gacuaccccg agcccgagga ggugcccccg gaggucaucu ccaucuacaa cuccacccgg      240

gaccuccugc aggagaaggc cagccgccgg gccgccgccu gcgagcgcga gcgguccgac      300

gaggaguacu acgcgaagga gguguacaag aucgacaugc cgcccuucuu ccccagcgag      360

aacgccaucc cgcccaccuu cuaccgcccc uacuuccgga ucgugcgcuu cgacgucucc      420

gccauggaga agaacgccag caaccuggug aaggcggagu uccggguguu ccgccuccag      480

aaccccaagg cccggguccc cgagcagcgc aucgagcugu accagauccu gaaguccaag      540

gaccucacga gccccaccca gcgguacauc gacuccaagg uggugaagac ccgcgccgag      600

ggggaguggc ugagcuucga cgucaccgac gccgugcacg aguggcugca ccacaaggac      660

cggaaccucg gcuucaagau cucccugcac ugccccugcu gcacguucgu gcccagcaac      720

aacuacauca ucccgaacaa guccgaggag cuggaggccc gcuucgcggg gaucgacggc      780

accagcaccu acaccagcgg ggaccagaag acgaucaagu ccacccggaa gaagaacagc      840

ggcaagacgc cccaccuccu gcugaugcuc cugcccuccu accgccugga gagccagcag      900

accaaccggc gcaagaagcg cgcccucgac gccgccuacu gcuuccggaa cguccaggac      960

aacugcugcc ugcgcccccu guacaucgac uucaagcggg accucggcug gaaguggauc     1020

cacgagccga agggguacaa cgccaacuuc ugcgcgggcg ccugccccua ccuguggucc     1080

agcgacaccc agcacucccg cgugcugagc cucuacaaca ccaucaaccc cgaggccucc     1140

gccagccccu gcugcguguc ccaggaccug gagccgcuga ccauccucua cuacaucggg     1200

aagaccccca agaucgagca gcugagcaac augaucguca aguccugcaa gugcagcuga     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  1566
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt1)

<400>  1566
gggagaaagc uuaccaugaa gaugcaccuc cagcgcgccc ucguggugcu ggcccugcuc       60

aacuucgcga ccgugagccu gucccugagc acgugcacca cccucgacuu cggccacauc      120

aagaagaagc ggguggaggc cauccgcggg cagauccugu ccaagcugcg gcucaccagc      180

ccgcccgagc ccaccgucau gacgcacgug cccuaccagg ugcuggcccu guacaacucc      240

acccgcgagc uccuggagga gaugcacggc gagcgggagg aggggugcac ccaggagaac      300

accgagagcg aguacuacgc caaggagauc cacaaguucg acaugaucca gggccuggcc      360

gagcacaacg agcucgcggu cugccccaag gggaucacgu ccaagguguu ccgcuucaac      420

gugagcuccg ucgagaagaa ccggaccaac cuguuccgcg ccgaguuccg ggugcugcgc      480

gugccgaacc ccagcuccaa gcggaacgag cagcgcaucg agcuguucca gauccugcgg      540

cccgacgagc acaucgccaa gcagcgcuac aucggcggca agaaccugcc cacccggggg      600

accgccgagu ggcucagcuu cgacgucacg gacaccgugc gcgaguggcu gcugcggcgc      660

gaguccaacc ucggccugga gaucagcauc cacugcccgu gccacaccuu ccagcccaac      720

ggggacaucc uggagaacau ccacgaggug auggagauca aguucaaggg cgucgacaac      780

gaggacgacc acgggcgggg cgaccucggc cgccugaaga agcagaagga ccaccacaac      840

ccccaccuga uccucaugau gaucccgccc caccggcugg acaaccccgg gcagggcggg      900

cagcgcaaga agcgcgcgcu ggacaccaac uacugcuucc ggaaccucga ggagaacugc      960

ugcgugcgcc cccuguacau cgacuuccgg caggaccugg gcuggaagug ggugcacgag     1020

cccaagggcu acuacgccaa cuucugcucc gggccgugcc ccuaccuccg cagcgccgac     1080

acgacccacu ccaccguccu gggccuguac aacacccuca accccgaggc cagcgccucc     1140

cccugcugcg ugccgcagga ccuggagccc cugacgaucc ucuacuacgu ggggcggacc     1200

cccaaggucg agcagcugag caacauggug gucaagagcu gcaagugcuc cugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  1567
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt1)

<400>  1567
gggagaaagc uuaccauggc ccccguggcc gucugggcgg cccuggccgu gggccucgag       60

cugugggccg ccgcgcacgc ccugccggcc cagguggccu ucacccccua cgcgcccgag      120

cccgggagca cgugccgccu ccgggaguac uacgaccaga ccgcccagau gugcugcucc      180

aagugcagcc cgggccagca cgccaagguc uucugcacca agaccuccga caccgugugc      240

gacagcugcg aggacuccac guacacccag cuguggaacu gggugcccga gugccugagc      300

ugcggguccc gcugcagcuc cgaccagguc gagacccagg ccugcacccg ggagcagaac      360

cgcaucugca cgugccggcc cggcugguac ugcgcccuca gcaagcagga ggggugccgc      420

cugugcgcgc cccugcggaa gugccgcccg ggcuucggcg uggcccggcc cgggaccgag      480

accuccgacg uggucugcaa gcccugcgcc cccggcaccu ucagcaacac gaccuccagc      540

accgacaucu gccgcccgca ccagaucugc aacguggugg ccauccccgg gaacgccucc      600

auggacgcgg ucugcaccag cacguccccc acccggagca uggcccccgg cgccgugcac      660

cucccgcagc ccguguccac ccgcagccag cacacccagc ccacgcccga gccgagcacc      720

gcccccucca ccagcuuccu gcugcccaug gggcccuccc cgcccgccga gggcagcacc      780

ggcgacuucg cgcuccccgu cgggcugauc gugggcguga cggcccuggg gcuccugauc      840

aucggcgucg ugaacugcgu gaucaugacc caggucaaga agaagccccu gugccuccag      900

cgggaggcca aggugccgca ccuccccgcc gacaaggccc gcggcaccca ggggcccgag      960

cagcagcacc uccugaucac cgcgccgucc agcuccagcu ccagccugga guccagcgcc     1020

uccgcccugg accggcgcgc ccccacgcgg aaccagcccc aggcgcccgg cguggaggcc     1080

agcggggccg gcgaggcccg cgccuccacc gggagcuccg acagcucccc gggcggccac     1140

gggacccagg ucaacgugac cugcaucguc aacgugugca gcagcuccga ccacagcucc     1200

cagugcagcu cccaggcgag cuccacgaug ggcgacaccg acagcucccc cagcgagucc     1260

cccaaggacg agcagguccc cuucagcaag gaggagugcg ccuuccgguc ccagcuggag     1320

accccggaga cccugcuggg gagcacggag gagaagcccc ucccccuggg cgugcccgac     1380

gccgggauga agccguccug aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  1568
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt1)

<400>  1568
gggagaaagc uuaccaugcc cgugaugcgc cuguucccgu gcuuccucca gcugcuggcc       60

ggccucgccc ugcccgcggu cccgccccag cagugggccc ugagcgccgg gaacggcucc      120

agcgaggugg aggugguccc cuuccaggag gugugggggc gguccuacug ccgcgcccuc      180

gagcggcugg uggacgucgu gagcgaguac cccuccgagg uggagcacau guucagcccc      240

uccugcguca gccugcuccg cugcaccggc ugcugcgggg acgagaaccu gcacugcgug      300

cccguggaga ccgccaacgu cacgaugcag cugcucaaga uccgguccgg cgaccgcccg      360

agcuacgugg agcugaccuu cucccagcac gugcggugcg agugccgccc ccugcgggag      420

aagaugaagc ccgagcgccg gcgccccaag ggccggggga agcgccggcg cgagaagcag      480

cggccgaccg acugccaccu cugcggcgac gcgguccccc gccggugagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  1569
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt1)

<400>  1569
gggagaaagc uuaccaugac cgaccgccag accgacacgg cccccagccc guccuaccac       60

cuccugcccg gccggcgccg gaccguggac gccgcggcca gccgcgggca gggccccgag      120

cccgcccccg ggggcggggu cgagggcgug ggcgcccgcg ggguggcccu gaagcuguuc      180

guccagcucc ugggcugcuc ccgguucggg ggcgcggugg ugcgggccgg ggaggccgag      240

cccagcggcg ccgcgcgcuc cgccagcucc ggccgggagg agccccagcc cgaggagggg      300

gaggaggagg aggagaagga ggaggagcgc ggcccgcagu ggcggcuggg ggcccgcaag      360

cccggcagcu ggaccggcga ggccgccguc ugcgcggacu ccgcccccgc cgcccgggcc      420

ccgcaggcgc ucgcccgcgc cagcgggcgg ggcgggcgcg uggcccggcg cggcgccgag      480

gaguccgggc cgccccacag ccccucccgg cgcggcagcg cgucccgggc cggccccggg      540

cgcgccagcg agaccaugaa cuuccugcug uccugggugc acuggagccu cgcccugcug      600

cucuaccugc accacgccaa guggucccag gcggccccga uggccgaggg cgggggccag      660

aaccaccacg aggucgugaa guucauggac guguaccagc gcagcuacug ccaccccauc      720

gagacgcugg ucgacaucuu ccaggaguac cccgacgaga ucgaguacau cuucaagccc      780

agcugcgugc cgcucaugcg gugcgggggc ugcugcaacg acgagggccu ggagugcgug      840

cccaccgagg aguccaacau caccaugcag aucaugcgca ucaagcccca ccaggggcag      900

cacaucggcg agaugagcuu ccugcagcac aacaagugcg agugccggcc caagaaggac      960

cgcgcccggc aggagaagaa guccguccgc gggaagggca aggggcagaa gcggaagcgc     1020

aagaaguccc gguacaagag cuggagcgug uacgugggcg cgcgcugcug ccucaugccg     1080

uggucccugc ccggccccca ccccugcggg ccgugcagcg agcggcgcaa gcaccuguuc     1140

guccaggacc cccagaccug caagugcucc ugcaagaaca cggacagccg gugcaaggcc     1200

cgccagcucg agcugaacga gcggaccugc cgcugcgaca agccccggcg cugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  1570
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt1)

<400>  1570
gggagaaagc uuaccaugaa cuuccugcuc agcugggugc acuggucccu ggcccugcuc       60

cuguaccugc accacgccaa guggagccag gcggccccca uggccgaggg cgggggccag      120

aaccaccacg aggucgugaa guucauggac guguaccagc gcuccuacug ccacccgauc      180

gagacccucg ucgacaucuu ccaggaguac cccgacgaga ucgaguacau cuucaagccc      240

agcugcgugc cccugaugcg gugcgggggc ugcugcaacg acgaggggcu ggagugcgug      300

ccgaccgagg aguccaacau cacgaugcag aucaugcgca ucaagcccca ccagggccag      360

cacaucggcg agaugagcuu ccuccagcac aacaagugcg agugccggcc caagaaggac      420

cgcgcccggc aggagaagaa guccguccgc gggaagggca aggggcagaa gcggaagcgc      480

aagaaguccc gguacaagag cuggagcgug uacgugggcg cccgcugcug ccugaugccc      540

uggucccugc cggggcccca ccccugcggc cccugcagcg agcggcgcaa gcaccucuuc      600

guccaggacc cgcagaccug caagugcucc ugcaagaaca ccgacagccg gugcaaggcg      660

cgccagcugg agcugaacga gcggaccugc cgcugcgaca agccccggcg cugaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  1571
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt1)

<400>  1571
gggagaaagc uuaccaugag cccccugcuc cgccggcugc ugcucgccgc ccugcugcag       60

cucgcgccgg cccaggcccc cgugucccag cccgacgccc ccggccacca gcgcaagguc      120

gugagcugga ucgacgugua cacccgggcg accugccagc cgcgcgaggu cguggugccc      180

cugacggucg agcugauggg gaccguggcc aagcagcucg ugcccuccug cgucaccgug      240

cagcggugcg gcgggugcug ccccgacgac ggccuggagu gcgugccgac cgggcagcac      300

cagguccgca ugcagauccu gaugauccgg uaccccagcu cccagcucgg cgagaugagc      360

cuggaggagc acucccagug cgagugccgc cccaagaaga aggacagcgc cgugaagccc      420

gaccgggccg ccacgccgca ccaccgcccc cagccccggu ccgugcccgg cugggacagc      480

gcgccggggg cccccucccc cgccgacauc acccacccca ccccggcccc cggccccagc      540

gcccacgcgg cccccuccac cacgagcgcc cugaccccgg ggcccgccgc cgcggccgcc      600

gacgccgccg cguccagcgu cgccaagggc ggggccugag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  1572
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt1)

<400>  1572
gggagaaagc uuaccaugca ccuccugggc uucuucagcg uggccugcuc ccugcuggcc       60

gcggcccucc ugcccgggcc gcgcgaggcc cccgccgccg cggccgccuu cgagagcggc      120

cuggaccucu ccgacgccga gcccgacgcg ggggaggcca ccgccuacgc cagcaaggac      180

cuggaggagc agcugcgguc cgucagcucc guggacgagc ucaugaccgu gcuguacccc      240

gaguacugga agauguacaa gugccagcug cgcaagggcg gguggcagca caaccgggag      300

caggccaacc ucaacagccg cacggaggag accaucaagu ucgcggccgc ccacuacaac      360

accgagaucc ugaaguccau cgacaacgag uggcggaaga cccagugcau gccgcgcgag      420

gucugcaucg acgugggcaa ggaguucggc guggccacga acaccuucuu caagccgccc      480

ugcgucagcg uguaccggug cgggggcugc ugcaacuccg aggggcugca gugcaugaac      540

accagcaccu ccuaccucag caagacgcug uucgagauca ccgugccccu gucccagggc      600

cccaagcccg ucaccaucag cuucgccaac cacaccuccu gccgcugcau gagcaagcuc      660

gacguguacc gccaggugca cuccaucauc cggcggagcc ugcccgcgac gcugccccag      720

ugccaggccg ccaacaagac cugcccgacc aacuacaugu ggaacaacca caucugccgc      780

ugccucgccc aggaggacuu cauguucagc uccgacgccg gggacgacag caccgacggc      840

uuccacgaca ucugcggccc caacaaggag cuggacgagg agacgugcca gugcgucugc      900

cgggcggggc ugcgccccgc cuccugcggc ccccacaagg agcucgaccg gaacagcugc      960

cagugcgugu gcaagaacaa gcuguucccg ucccagugcg gggccaaccg cgaguucgac     1020

gagaacacgu gccagugcgu gugcaagcgg accugccccc gcaaccagcc ccugaacccc     1080

ggcaagugcg ccugcgagug caccgagagc ccgcagaagu gccuccugaa gggcaagaag     1140

uuccaccacc agaccugcuc cugcuaccgg cgccccugca ccaaccggca gaaggccugc     1200

gagcccgggu ucagcuacuc cgaggagguc ugccgcugcg ugcccagcua cuggaagcgc     1260

ccgcagaugu ccugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  1573
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt1)

<400>  1573
gggagaaagc uuaccaugua ccgcgagugg guggucguga acguguucau gaugcuguac       60

guccagcucg ugcagggcag cuccaacgag cacgggcccg ugaagcggag cucccagagc      120

acccuggagc gcuccgagca gcagauccgg gccgccagcu cccuggagga gcuccugcgc      180

aucacccaca gcgaggacug gaagcugugg cggugccgcc uccggcugaa guccuucacg      240

agcauggacu cccgcagcgc gucccaccgg agcacccgcu ucgccgccac cuucuacgac      300

aucgagaccc ugaaggucau cgacgaggag uggcagcgga cgcagugcuc cccgcgcgag      360

accugcgugg agguggccag cgagcucggc aaguccacca acaccuucuu caagccgccc      420

ugcgucaacg uguuccggug cgggggcugc ugcaacgagg agagccugau cugcaugaac      480

acguccacca gcuacaucag caagcagcug uucgagaucu ccgugccccu caccagcguc      540

cccgagcugg ugcccgugaa ggucgccaac cacaccgggu gcaagugccu gcccacggcg      600

ccccgccacc cguacuccau cauccggcgc agcauccaga uccccgagga ggaccggugc      660

ucccacagca agaagcucug ccccaucgac augcuguggg acuccaacaa gugcaagugc      720

gugcugcagg aggagaaccc ccucgccggc accgaggacc acagccaccu ccaggagccg      780

gcccugugcg gcccccacau gauguucgac gaggaccgcu gcgagugcgu gugcaagacc      840

cccugcccca aggaccugau ccagcacccg aagaacugcu ccugcuucga gugcaaggag      900

agccuggaga ccugcugcca gaagcacaag cuguuccacc ccgacacgug cuccugcgag      960

gaccggugcc ccuuccacac ccgccccugc gccagcggga agaccgcgug cgccaagcac     1020

ugccgguucc cgaaggagaa gcgcgccgcc cagggccccc acucccgcaa gaaccccuga     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  1574
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt2)

<400>  1574
gggagaaagc uuaccaugga cuccgacgag accggcuucg agcacuccgg ccucuggguc       60

uccguccucg ccggccuccu ccucggcgcc ugccaggccc accccauccc cgacuccucc      120

ccccuccucc aguucggcgg ccagguccgc cagcgcuacc ucuacaccga cgacgcccag      180

cagaccgagg cccaccucga gauccgcgag gacggcaccg ucggcggcgc cgccgaccag      240

ucccccgagu cccuccucca gcucaaggcc cucaagcccg gcgucaucca gauccucggc      300

gucaagaccu cccgcuuccu cugccagcgc cccgacggcg cccucuacgg cucccuccac      360

uucgaccccg aggccugcuc cuuccgcgag cuccuccucg aggacggcua caacgucuac      420

caguccgagg cccacggccu cccccuccac cuccccggca acaagucccc ccaccgcgac      480

cccgcccccc gcggccccgc ccgcuuccuc ccccuccccg gccucccccc cgcccucccc      540

gagccccccg gcauccucgc cccccagccc cccgacgucg gcuccuccga cccccucucc      600

auggucggcc ccucccaggg ccgcuccccc uccuacgccu ccugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  1575
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt2)

<400>  1575
gggagaaagc uuaccaugca cuccuucccc ccccuccucc uccuccucuu cuggggcguc       60

gucucccacu ccuuccccgc cacccucgag acccaggagc aggacgucga ccucguccag      120

aaguaccucg agaaguacua caaccucaag aacgacggcc gccaggucga gaagcgccgc      180

aacuccggcc ccgucgucga gaagcucaag cagaugcagg aguucuucgg ccucaagguc      240

accggcaagc ccgacgccga gacccucaag gucaugaagc agccccgcug cggcgucccc      300

gacgucgccc aguucguccu caccgagggc aacccccgcu gggagcagac ccaccucacc      360

uaccgcaucg agaacuacac ccccgaccuc ccccgcgccg acgucgacca cgccaucgag      420

aaggccuucc agcucugguc caacgucacc ccccucaccu ucaccaaggu cuccgagggc      480

caggccgaca ucaugaucuc cuucguccgc ggcgaccacc gcgacaacuc ccccuucgac      540

ggccccggcg gcaaccucgc ccacgccuuc cagcccggcc ccggcaucgg cggcgacgcc      600

cacuucgacg aggacgagcg cuggaccaac aacuuccgcg aguacaaccu ccaccgcguc      660

gccgcccacg agcucggcca cucccucggc cucucccacu ccaccgacau cggcgcccuc      720

auguaccccu ccuacaccuu cuccggcgac guccagcucg cccaggacga caucgacggc      780

auccaggcca ucuacggccg cucccagaac cccguccagc ccaucggccc ccagaccccc      840

aaggccugcg acuccaagcu caccuucgac gccaucacca ccauccgcgg cgaggucaug      900

uucuucaagg accgcuucua caugcgcacc aaccccuucu accccgaggu cgagcucaac      960

uucaucuccg ucuucuggcc ccagcucccc aacggccucg aggccgccua cgaguucgcc     1020

gaccgcgacg agguccgcuu cuucaagggc aacaaguacu gggccgucca gggccagaac     1080

guccuccacg gcuaccccaa ggacaucuac uccuccuucg gcuucccccg caccgucaag     1140

cacaucgacg ccgcccucuc cgaggagaac accggcaaga ccuacuucuu cgucgccaac     1200

aaguacuggc gcuacgacga guacaagcgc uccauggacc ccggcuaccc caagaugauc     1260

gcccacgacu uccccggcau cggccacaag gucgacgccg ucuucaugaa ggacggcuuc     1320

uucuacuucu uccacggcac ccgccaguac aaguucgacc ccaagaccaa gcgcauccuc     1380

acccuccaga aggccaacuc cugguucaac ugccgcaaga acugaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  1576
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt2)

<400>  1576
gggagaaagc uuaccaugca cuccuucccc ccccuccucc uccuccucuu cuggggcguc       60

gucucccacu ccuucguccu caccgagggc aacccccgcu gggagcagac ccaccucacc      120

uaccgcaucg agaacuacac ccccgaccuc ccccgcgccg acgucgacca cgccaucgag      180

aaggccuucc agcucugguc caacgucacc ccccucaccu ucaccaaggu cuccgagggc      240

caggccgaca ucaugaucuc cuucguccgc ggcgaccacc gcgacaacuc ccccuucgac      300

ggccccggcg gcaaccucgc ccacgccuuc cagcccggcc ccggcaucgg cggcgacgcc      360

cacuucgacg aggacgagcg cuggaccaac aacuuccgcg aguacaaccu ccaccgcguc      420

gccgcccacg agcucggcca cucccucggc cucucccacu ccaccgacau cggcgcccuc      480

auguaccccu ccuacaccuu cuccggcgac guccagcucg cccaggacga caucgacggc      540

auccaggcca ucuacggccg cucccagaac cccguccagc ccaucggccc ccagaccccc      600

aaggccugcg acuccaagcu caccuucgac gccaucacca ccauccgcgg cgaggucaug      660

uucuucaagg accgcuucua caugcgcacc aaccccuucu accccgaggu cgagcucaac      720

uucaucuccg ucuucuggcc ccagcucccc aacggccucg aggccgccua cgaguucgcc      780

gaccgcgacg agguccgcuu cuucaagggc aacaaguacu gggccgucca gggccagaac      840

guccuccacg gcuaccccaa ggacaucuac uccuccuucg gcuucccccg caccgucaag      900

cacaucgacg ccgcccucuc cgaggagaac accggcaaga ccuacuucuu cgucgccaac      960

aaguacuggc gcuacgacga guacaagcgc uccauggacc ccggcuaccc caagaugauc     1020

gcccacgacu uccccggcau cggccacaag gucgacgccg ucuucaugaa ggacggcuuc     1080

uucuacuucu uccacggcac ccgccaguac aaguucgacc ccaagaccaa gcgcauccuc     1140

acccuccaga aggccaacuc cugguucaac ugccgcaaga acugaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  1577
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt2)

<400>  1577
gggagaaagc uuaccaugaa gaagaacauc cucaagaucc ucauggacuc cuacuccaag       60

gaguccaaga uccagaccgu ccgccgcguc accuccgucu cccuccucgc cgucuaccuc      120

accaugaaca ccuccucccu cguccucgcc aagcccaucg agaacaccaa cgacaccucc      180

aucaagaacg ucgagaagcu ccgcaacgcc cccaacgagg agaacuccaa gaaggucgag      240

gacuccaaga acgacaaggu cgagcacguc aagaacaucg aggaggccaa ggucgagcag      300

gucgcccccg aggucaaguc caaguccacc cuccgcuccg ccuccaucgc caacaccaac      360

uccgagaagu acgacuucga guaccucaac ggccucuccu acaccgagcu caccaaccuc      420

aucaagaaca ucaaguggaa ccagaucaac ggccucuuca acuacuccac cggcucccag      480

aaguucuucg gcgacaagaa ccgcguccag gccaucauca acgcccucca ggaguccggc      540

cgcaccuaca ccgccaacga caugaagggc aucgagaccu ucaccgaggu ccuccgcgcc      600

ggcuucuacc ucggcuacua caacgacggc cucuccuacc ucaacgaccg caacuuccag      660

gacaagugca uccccgccau gaucgccauc cagaagaacc ccaacuucaa gcucggcacc      720

gccguccagg acgaggucau caccucccuc ggcaagcuca ucggcaacgc cuccgccaac      780

gccgaggucg ucaacaacug cguccccguc cucaagcagu uccgcgagaa ccucaaccag      840

uacgcccccg acuacgucaa gggcaccgcc gucaacgagc ucaucaaggg caucgaguuc      900

gacuucuccg gcgccgccua cgagaaggac gucaagacca ugcccuggua cggcaagauc      960

gaccccuuca ucaacgagcu caaggcccuc ggccucuacg gcaacaucac cuccgccacc     1020

gagugggccu ccgacgucgg caucuacuac cucuccaagu ucggccucua cuccaccaac     1080

cgcaacgaca ucguccaguc ccucgagaag gccgucgaca uguacaagua cggcaagauc     1140

gccuucgucg ccauggagcg caucaccugg gacuacgacg gcaucggcuc caacggcaag     1200

aaggucgacc acgacaaguu ccucgacgac gccgagaagc acuaccuccc caagaccuac     1260

accuucgaca acggcaccuu caucauccgc gccggcgaca aggucuccga ggagaagauc     1320

aagcgccucu acugggccuc ccgcgagguc aagucccagu uccaccgcgu cgucggcaac     1380

gacaaggccc ucgaggucgg caacgccgac gacguccuca ccaugaagau cuucaacucc     1440

cccgaggagu acaaguucaa caccaacauc aacggcgucu ccaccgacaa cggcggccuc     1500

uacaucgagc cccgcggcac cuucuacacc uacgagcgca ccccccagca guccaucuuc     1560

ucccucgagg agcucuuccg ccacgaguac acccacuacc uccaggcccg cuaccucguc     1620

gacggccucu ggggccaggg ccccuucuac gagaagaacc gccucaccug guucgacgag     1680

ggcaccgccg aguucuucgc cggcuccacc cgcaccuccg gcguccuccc ccgcaagucc     1740

auccucggcu accucgccaa ggacaagguc gaccaccgcu acucccucaa gaagacccuc     1800

aacuccggcu acgacgacuc cgacuggaug uucuacaacu acggcuucgc cgucgcccac     1860

uaccucuacg agaaggacau gcccaccuuc aucaagauga acaaggccau ccucaacacc     1920

gacgucaagu ccuacgacga gaucaucaag aagcucuccg acgacgccaa caagaacacc     1980

gaguaccaga accacaucca ggagcucgcc gacaaguacc agggcgccgg caucccccuc     2040

gucuccgacg acuaccucaa ggaccacggc uacaagaagg ccuccgaggu cuacuccgag     2100

aucuccaagg ccgccucccu caccaacacc uccgucaccg ccgagaaguc ccaguacuuc     2160

aacaccuuca cccuccgcgg caccuacacc ggcgagaccu ccaagggcga guucaaggac     2220

ugggacgaga uguccaagaa gcucgacggc acccucgagu cccucgccaa gaacuccugg     2280

uccggcuaca agacccucac cgccuacuuc accaacuacc gcgucaccuc cgacaacaag     2340

guccaguacg acgucgucuu ccacggcguc cucaccgaca acgccgacau cuccaacaac     2400

aaggccccca ucgccaaggu caccggcccc uccaccggcg ccgucggccg caacaucgag     2460

uucuccggca aggacuccaa ggacgaggac ggcaagaucg ucuccuacga cugggacuuc     2520

ggcgacggcg ccaccucccg cggcaagaac uccguccacg ccuacaagaa ggccggcacc     2580

uacaacguca cccucaaggu caccgacgac aagggcgcca ccgccaccga guccuucacc     2640

aucgagauca agaacgagga caccaccacc cccaucacca aggagaugga gcccaacgac     2700

gacaucaagg aggccaacgg ccccaucguc gagggcguca ccgucaaggg cgaccucaac     2760

ggcuccgacg acgccgacac cuucuacuuc gacgucaagg aggacggcga cgucaccauc     2820

gagcuccccu acuccggcuc cuccaacuuc accuggcucg ucuacaagga gggcgacgac     2880

cagaaccaca ucgccuccgg caucgacaag aacaacucca aggucggcac cuucaagucc     2940

accaagggcc gccacuacgu cuucaucuac aagcacgacu ccgccuccaa caucuccuac     3000

ucccucaaca ucaagggccu cggcaacgag aagcucaagg agaaggagaa caacgacucc     3060

uccgacaagg ccaccgucau ccccaacuuc aacaccacca ugcagggcuc ccuccucggc     3120

gacgacuccc gcgacuacua cuccuucgag gucaaggagg agggcgaggu caacaucgag     3180

cucgacaaga aggacgaguu cggcgucacc uggacccucc accccgaguc caacaucaac     3240

gaccgcauca ccuacggcca ggucgacggc aacaaggucu ccaacaaggu caagcuccgc     3300

cccggcaagu acuaccuccu cgucuacaag uacuccggcu ccggcaacua cgagcuccgc     3360

gucaacaagu gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  1578
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt2)

<400>  1578
gggagaaagc uuaccaugaa gugggucacc uucaucuccc uccucuuccu cuucuccucc       60

gccuacucca ucgccaacac caacuccgag aaguacgacu ucgaguaccu caacggccuc      120

uccuacaccg agcucaccaa ccucaucaag aacaucaagu ggaaccagau caacggccuc      180

uucaacuacu ccaccggcuc ccagaaguuc uucggcgaca agaaccgcgu ccaggccauc      240

aucaacgccc uccaggaguc cggccgcacc uacaccgcca acgacaugaa gggcaucgag      300

accuucaccg agguccuccg cgccggcuuc uaccucggcu acuacaacga cggccucucc      360

uaccucaacg accgcaacuu ccaggacaag ugcauccccg ccaugaucgc cauccagaag      420

aaccccaacu ucaagcucgg caccgccguc caggacgagg ucaucaccuc ccucggcaag      480

cucaucggca acgccuccgc caacgccgag gucgucaaca acugcguccc cguccucaag      540

caguuccgcg agaaccucaa ccaguacgcc cccgacuacg ucaagggcac cgccgucaac      600

gagcucauca agggcaucga guucgacuuc uccggcgccg ccuacgagaa ggacgucaag      660

accaugcccu gguacggcaa gaucgacccc uucaucaacg agcucaaggc ccucggccuc      720

uacggcaaca ucaccuccgc caccgagugg gccuccgacg ucggcaucua cuaccucucc      780

aaguucggcc ucuacuccac caaccgcaac gacaucgucc agucccucga gaaggccguc      840

gacauguaca aguacggcaa gaucgccuuc gucgccaugg agcgcaucac cugggacuac      900

gacggcaucg gcuccaacgg caagaagguc gaccacgaca aguuccucga cgacgccgag      960

aagcacuacc uccccaagac cuacaccuuc gacaacggca ccuucaucau ccgcgccggc     1020

gacaaggucu ccgaggagaa gaucaagcgc cucuacuggg ccucccgcga ggucaagucc     1080

caguuccacc gcgucgucgg caacgacaag gcccucgagg ucggcaacgc cgacgacguc     1140

cucaccauga agaucuucaa cucccccgag gaguacaagu ucaacaccaa caucaacggc     1200

gucuccaccg acaacggcgg ccucuacauc gagccccgcg gcaccuucua caccuacgag     1260

cgcacccccc agcaguccau cuucucccuc gaggagcucu uccgccacga guacacccac     1320

uaccuccagg cccgcuaccu cgucgacggc cucuggggcc agggccccuu cuacgagaag     1380

aaccgccuca ccugguucga cgagggcacc gccgaguucu ucgccggcuc cacccgcacc     1440

uccggcgucc ucccccgcaa guccauccuc ggcuaccucg ccaaggacaa ggucgaccac     1500

cgcuacuccc ucaagaagac ccucaacucc ggcuacgacg acuccgacug gauguucuac     1560

aacuacggcu ucgccgucgc ccacuaccuc uacgagaagg acaugcccac cuucaucaag     1620

augaacaagg ccauccucaa caccgacguc aaguccuacg acgagaucau caagaagcuc     1680

uccgacgacg ccaacaagaa caccgaguac cagaaccaca uccaggagcu cgccgacaag     1740

uaccagggcg ccggcauccc ccucgucucc gacgacuacc ucaaggacca cggcuacaag     1800

aaggccuccg aggucuacuc cgagaucucc aaggccgccu cccucaccaa caccuccguc     1860

accgccgaga agucccagua cuucaacacc uucacccucc gcggcaccua caccggcgag     1920

accuccaagg gcgaguucaa ggacugggac gagaugucca agaagcucga cggcacccuc     1980

gagucccucg ccaagaacuc cugguccggc uacaagaccc ucaccgccua cuucaccaac     2040

uaccgcguca ccuccgacaa caagguccag uacgacgucg ucuuccacgg cguccucacc     2100

gacaacgccg acaucuccaa caacaaggcc cccaucgcca aggucaccgg ccccuccacc     2160

ggcgccgucg gccgcaacau cgaguucucc ggcaaggacu ccaaggacga ggacggcaag     2220

aucgucuccu acgacuggga cuucggcgac ggcgccaccu cccgcggcaa gaacuccguc     2280

cacgccuaca agaaggccgg caccuacaac gucacccuca aggucaccga cgacaagggc     2340

gccaccgcca ccgaguccuu caccaucgag aucaagaacg aggacaccac cacccccauc     2400

accaaggaga uggagcccaa cgacgacauc aaggaggcca acggccccau cgucgagggc     2460

gucaccguca agggcgaccu caacggcucc gacgacgccg acaccuucua cuucgacguc     2520

aaggaggacg gcgacgucac caucgagcuc cccuacuccg gcuccuccaa cuucaccugg     2580

cucgucuaca aggagggcga cgaccagaac cacaucgccu ccggcaucga caagaacaac     2640

uccaaggucg gcaccuucaa guccaccaag ggccgccacu acgucuucau cuacaagcac     2700

gacuccgccu ccaacaucuc cuacucccuc aacaucaagg gccucggcaa cgagaagcuc     2760

aaggagaagg agaacaacga cuccuccgac aaggccaccg ucauccccaa cuucaacacc     2820

accaugcagg gcucccuccu cggcgacgac ucccgcgacu acuacuccuu cgaggucaag     2880

gaggagggcg aggucaacau cgagcucgac aagaaggacg aguucggcgu caccuggacc     2940

cuccaccccg aguccaacau caacgaccgc aucaccuacg gccaggucga cggcaacaag     3000

gucuccaaca aggucaagcu ccgccccggc aaguacuacc uccucgucua caaguacucc     3060

ggcuccggca acuacgagcu ccgcgucaac aagugaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  1579
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt2)

<400>  1579
gggagaaagc uuaccaugaa gugggucacc uucaucuccc uccucuuccu cuucuccucc       60

gccuacucca ugaagaagaa cauccucaag auccucaugg acuccuacuc caaggagucc      120

aagauccaga ccguccgccg cgucaccucc gucucccucc ucgccgucua ccucaccaug      180

aacaccuccu cccucguccu cgccaagccc aucgagaaca ccaacgacac cuccaucaag      240

aacgucgaga agcuccgcaa cgcccccaac gaggagaacu ccaagaaggu cgaggacucc      300

aagaacgaca aggucgagca cgucaagaac aucgaggagg ccaaggucga gcaggucgcc      360

cccgagguca aguccaaguc cacccuccgc uccgccuccc gccgccgccg caagcgcauc      420

gccaacacca acuccgagaa guacgacuuc gaguaccuca acggccucuc cuacaccgag      480

cucaccaacc ucaucaagaa caucaagugg aaccagauca acggccucuu caacuacucc      540

accggcuccc agaaguucuu cggcgacaag aaccgcgucc aggccaucau caacgcccuc      600

caggaguccg gccgcaccua caccgccaac gacaugaagg gcaucgagac cuucaccgag      660

guccuccgcg ccggcuucua ccucggcuac uacaacgacg gccucuccua ccucaacgac      720

cgcaacuucc aggacaagug cauccccgcc augaucgcca uccagaagaa ccccaacuuc      780

aagcucggca ccgccgucca ggacgagguc aucaccuccc ucggcaagcu caucggcaac      840

gccuccgcca acgccgaggu cgucaacaac ugcguccccg uccucaagca guuccgcgag      900

aaccucaacc aguacgcccc cgacuacguc aagggcaccg ccgucaacga gcucaucaag      960

ggcaucgagu ucgacuucuc cggcgccgcc uacgagaagg acgucaagac caugcccugg     1020

uacggcaaga ucgaccccuu caucaacgag cucaaggccc ucggccucua cggcaacauc     1080

accuccgcca ccgagugggc cuccgacguc ggcaucuacu accucuccaa guucggccuc     1140

uacuccacca accgcaacga caucguccag ucccucgaga aggccgucga cauguacaag     1200

uacggcaaga ucgccuucgu cgccauggag cgcaucaccu gggacuacga cggcaucggc     1260

uccaacggca agaaggucga ccacgacaag uuccucgacg acgccgagaa gcacuaccuc     1320

cccaagaccu acaccuucga caacggcacc uucaucaucc gcgccggcga caaggucucc     1380

gaggagaaga ucaagcgccu cuacugggcc ucccgcgagg ucaaguccca guuccaccgc     1440

gucgucggca acgacaaggc ccucgagguc ggcaacgccg acgacguccu caccaugaag     1500

aucuucaacu cccccgagga guacaaguuc aacaccaaca ucaacggcgu cuccaccgac     1560

aacggcggcc ucuacaucga gccccgcggc accuucuaca ccuacgagcg caccccccag     1620

caguccaucu ucucccucga ggagcucuuc cgccacgagu acacccacua ccuccaggcc     1680

cgcuaccucg ucgacggccu cuggggccag ggccccuucu acgagaagaa ccgccucacc     1740

ugguucgacg agggcaccgc cgaguucuuc gccggcucca cccgcaccuc cggcguccuc     1800

ccccgcaagu ccauccucgg cuaccucgcc aaggacaagg ucgaccaccg cuacucccuc     1860

aagaagaccc ucaacuccgg cuacgacgac uccgacugga uguucuacaa cuacggcuuc     1920

gccgucgccc acuaccucua cgagaaggac augcccaccu ucaucaagau gaacaaggcc     1980

auccucaaca ccgacgucaa guccuacgac gagaucauca agaagcucuc cgacgacgcc     2040

aacaagaaca ccgaguacca gaaccacauc caggagcucg ccgacaagua ccagggcgcc     2100

ggcauccccc ucgucuccga cgacuaccuc aaggaccacg gcuacaagaa ggccuccgag     2160

gucuacuccg agaucuccaa ggccgccucc cucaccaaca ccuccgucac cgccgagaag     2220

ucccaguacu ucaacaccuu cacccuccgc ggcaccuaca ccggcgagac cuccaagggc     2280

gaguucaagg acugggacga gauguccaag aagcucgacg gcacccucga gucccucgcc     2340

aagaacuccu gguccggcua caagacccuc accgccuacu ucaccaacua ccgcgucacc     2400

uccgacaaca agguccagua cgacgucguc uuccacggcg uccucaccga caacgccgac     2460

aucuccaaca acaaggcccc caucgccaag gucaccggcc ccuccaccgg cgccgucggc     2520

cgcaacaucg aguucuccgg caaggacucc aaggacgagg acggcaagau cgucuccuac     2580

gacugggacu ucggcgacgg cgccaccucc cgcggcaaga acuccgucca cgccuacaag     2640

aaggccggca ccuacaacgu cacccucaag gucaccgacg acaagggcgc caccgccacc     2700

gaguccuuca ccaucgagau caagaacgag gacaccacca cccccaucac caaggagaug     2760

gagcccaacg acgacaucaa ggaggccaac ggccccaucg ucgagggcgu caccgucaag     2820

ggcgaccuca acggcuccga cgacgccgac accuucuacu ucgacgucaa ggaggacggc     2880

gacgucacca ucgagcuccc cuacuccggc uccuccaacu ucaccuggcu cgucuacaag     2940

gagggcgacg accagaacca caucgccucc ggcaucgaca agaacaacuc caaggucggc     3000

accuucaagu ccaccaaggg ccgccacuac gucuucaucu acaagcacga cuccgccucc     3060

aacaucuccu acucccucaa caucaagggc cucggcaacg agaagcucaa ggagaaggag     3120

aacaacgacu ccuccgacaa ggccaccguc auccccaacu ucaacaccac caugcagggc     3180

ucccuccucg gcgacgacuc ccgcgacuac uacuccuucg aggucaagga ggagggcgag     3240

gucaacaucg agcucgacaa gaaggacgag uucggcguca ccuggacccu ccaccccgag     3300

uccaacauca acgaccgcau caccuacggc caggucgacg gcaacaaggu cuccaacaag     3360

gucaagcucc gccccggcaa guacuaccuc cucgucuaca aguacuccgg cuccggcaac     3420

uacgagcucc gcgucaacaa gugaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  1580
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt2)

<400>  1580
gggagaaagc uuaccaugaa cuuccucaag aucauccuca accgcggcaa gaccaugaag       60

cgcaagugcc ucuccaagcg ccucaugcuc gccaucacca uggccaccau cuucaccguc      120

aacuccaccc uccccaucua cgccgccguc gacaagaaca acgccaccgc cgccguccag      180

aacgagucca agcgcuacac cgucuccuac cucaagaccc ucaacuacua cgaccucguc      240

gaccuccucg ucaagaccga gaucgagaac cuccccgacc ucuuccagua cuccuccgac      300

gccaaggagu ucuacggcaa caagacccgc auguccuuca ucauggacga gaucggccgc      360

cgcgcccccc aguacaccga gaucgaccac aagggcaucc ccacccucgu cgaggucguc      420

cgcgccggcu ucuaccucgg cuuccacaac aaggagcuca acgagaucaa caagcgcucc      480

uucaaggagc gcgucauccc cuccauccuc gccauccaga agaaccccaa cuucaagcuc      540

ggcaccgagg uccaggacaa gaucgucucc gccaccggcc uccucgccgg caacgagacc      600

gccccccccg aggucgucaa caacuucacc cccauccucc aggacugcau caagaacauc      660

gaccgcuacg cccucgacga ccucaagucc aaggcccucu ucaacguccu cgccgccccc      720

accuacgaca ucaccgagua ccuccgcgcc accaaggaga agcccgagaa cacccccugg      780

uacggcaaga ucgacggcuu caucaacgag cucaagaagc ucgcccucua cggcaagauc      840

aacgacaaca acuccuggau caucgacaac ggcaucuacc acaucgcccc ccucggcaag      900

cuccacucca acaacaagau cggcaucgag acccucaccg aggucaugaa ggucuacccc      960

uaccucucca ugcagcaccu ccaguccgcc gaccagauca agcgccacua cgacuccaag     1020

gacgccgagg gcaacaagau cccccucgac aaguucaaga aggagggcaa ggagaaguac     1080

ugccccaaga ccuacaccuu cgacgacggc aaggucauca ucaaggccgg cgcccgcguc     1140

gaggaggaga aggucaagcg ccucuacugg gccuccaagg aggucaacuc ccaguucuuc     1200

cgcgucuacg gcaucgacaa gccccucgag gagggcaacc ccgacgacau ccucaccaug     1260

gucaucuaca acucccccga ggaguacaag cucaacuccg uccucuacgg cuacgacacc     1320

aacaacggcg gcauguacau cgagcccgag ggcaccuucu ucaccuacga gcgcgaggcc     1380

caggagucca ccuacacccu cgaggagcuc uuccgccacg aguacaccca cuaccuccag     1440

ggccgcuacg ccguccccgg ccaguggggc cgcaccaagc ucuacgacaa cgaccgccuc     1500

accugguacg aggagggcgg cgccgagcuc uucgccggcu ccacccgcac cuccggcauc     1560

cucccccgca aguccaucgu cuccaacauc cacaacacca cccgcaacaa ccgcuacaag     1620

cucuccgaca ccguccacuc caaguacggc gccuccuucg aguucuacaa cuacgccugc     1680

auguucaugg acuacaugua caacaaggac augggcaucc ucaacaagcu caacgaccuc     1740

gccaagaaca acgacgucga cggcuacgac aacuacaucc gcgaccucuc cuccaacuac     1800

gcccucaacg acaaguacca ggaccacaug caggagcgca ucgacaacua cgagaaccuc     1860

accguccccu ucgucgccga cgacuaccuc guccgccacg ccuacaagaa ccccaacgag     1920

aucuacuccg agaucuccga ggucgccaag cucaaggacg ccaaguccga ggucaagaag     1980

ucccaguacu ucuccaccuu cacccuccgc ggcuccuaca ccggcggcgc cuccaagggc     2040

aagcucgagg accagaaggc caugaacaag uucaucgacg acucccucaa gaagcucgac     2100

accuacuccu gguccggcua caagacccuc accgccuacu ucaccaacua caaggucgac     2160

uccuccaacc gcgucaccua cgacgucguc uuccacggcu accuccccaa cgagggcgac     2220

uccaagaacu cccuccccua cggcaagauc aacggcaccu acaagggcac cgagaaggag     2280

aagaucaagu ucuccuccga gggcuccuuc gaccccgacg gcaagaucgu cuccuacgag     2340

ugggacuucg gcgacggcaa caaguccaac gaggagaacc ccgagcacuc cuacgacaag     2400

gucggcaccu acaccgucaa gcucaagguc accgacgaca agggcgaguc cuccgucucc     2460

accaccaccg ccgagaucaa ggaccucucc gagaacaagc uccccgucau cuacaugcac     2520

guccccaagu ccggcgcccu caaccagaag gucgucuucu acggcaaggg caccuacgac     2580

cccgacggcu ccaucgccgg cuaccagugg gacuucggcg acggcuccga cuucuccucc     2640

gagcagaacc ccucccacgu cuacaccaag aagggcgagu acaccgucac ccuccgcguc     2700

auggacuccu ccggccagau guccgagaag accaugaaga ucaagaucac cgaccccguc     2760

uaccccaucg gcaccgagaa ggagcccaac aacuccaagg agaccgccuc cggccccauc     2820

guccccggca uccccgucuc cggcaccauc gagaacaccu ccgaccagga cuacuucuac     2880

uucgacguca ucacccccgg cgaggucaag aucgacauca acaagcucgg cuacggcggc     2940

gccaccuggg ucgucuacga cgagaacaac aacgccgucu ccuacgccac cgacgacggc     3000

cagaaccucu ccggcaaguu caaggccgac aagcccggcc gcuacuacau ccaccucuac     3060

auguucaacg gcuccuacau gcccuaccgc aucaacaucg agggcuccgu cggccgcuga     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  1581
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt2)

<400>  1581
gggagaaagc uuaccaugaa gcgcaagugc cucuccaagc gccucaugcu cgccaucacc       60

auggccacca ucuucaccgu caacuccacc cuccccaucu acgccgccgu cgacaagaac      120

aacgccaccg ccgccgucca gaacgagucc aagcgcuaca ccgucuccua ccucaagacc      180

cucaacuacu acgaccucgu cgaccuccuc gucaagaccg agaucgagaa ccuccccgac      240

cucuuccagu acuccuccga cgccaaggag uucuacggca acaagacccg cauguccuuc      300

aucauggacg agaucggccg ccgcgccccc caguacaccg agaucgacca caagggcauc      360

cccacccucg ucgaggucgu ccgcgccggc uucuaccucg gcuuccacaa caaggagcuc      420

aacgagauca acaagcgcuc cuucaaggag cgcgucaucc ccuccauccu cgccauccag      480

aagaacccca acuucaagcu cggcaccgag guccaggaca agaucgucuc cgccaccggc      540

cuccucgccg gcaacgagac cgcccccccc gaggucguca acaacuucac ccccauccuc      600

caggacugca ucaagaacau cgaccgcuac gcccucgacg accucaaguc caaggcccuc      660

uucaacgucc ucgccgcccc caccuacgac aucaccgagu accuccgcgc caccaaggag      720

aagcccgaga acacccccug guacggcaag aucgacggcu ucaucaacga gcucaagaag      780

cucgcccucu acggcaagau caacgacaac aacuccugga ucaucgacaa cggcaucuac      840

cacaucgccc cccucggcaa gcuccacucc aacaacaaga ucggcaucga gacccucacc      900

gaggucauga aggucuaccc cuaccucucc augcagcacc uccaguccgc cgaccagauc      960

aagcgccacu acgacuccaa ggacgccgag ggcaacaaga ucccccucga caaguucaag     1020

aaggagggca aggagaagua cugccccaag accuacaccu ucgacgacgg caaggucauc     1080

aucaaggccg gcgcccgcgu cgaggaggag aaggucaagc gccucuacug ggccuccaag     1140

gaggucaacu cccaguucuu ccgcgucuac ggcaucgaca agccccucga ggagggcaac     1200

cccgacgaca uccucaccau ggucaucuac aacucccccg aggaguacaa gcucaacucc     1260

guccucuacg gcuacgacac caacaacggc ggcauguaca ucgagcccga gggcaccuuc     1320

uucaccuacg agcgcgaggc ccaggagucc accuacaccc ucgaggagcu cuuccgccac     1380

gaguacaccc acuaccucca gggccgcuac gccguccccg gccagugggg ccgcaccaag     1440

cucuacgaca acgaccgccu caccugguac gaggagggcg gcgccgagcu cuucgccggc     1500

uccacccgca ccuccggcau ccucccccgc aaguccaucg ucuccaacau ccacaacacc     1560

acccgcaaca accgcuacaa gcucuccgac accguccacu ccaaguacgg cgccuccuuc     1620

gaguucuaca acuacgccug cauguucaug gacuacaugu acaacaagga caugggcauc     1680

cucaacaagc ucaacgaccu cgccaagaac aacgacgucg acggcuacga caacuacauc     1740

cgcgaccucu ccuccaacua cgcccucaac gacaaguacc aggaccacau gcaggagcgc     1800

aucgacaacu acgagaaccu caccgucccc uucgucgccg acgacuaccu cguccgccac     1860

gccuacaaga accccaacga gaucuacucc gagaucuccg aggucgccaa gcucaaggac     1920

gccaaguccg aggucaagaa gucccaguac uucuccaccu ucacccuccg cggcuccuac     1980

accggcggcg ccuccaaggg caagcucgag gaccagaagg ccaugaacaa guucaucgac     2040

gacucccuca agaagcucga caccuacucc ugguccggcu acaagacccu caccgccuac     2100

uucaccaacu acaaggucga cuccuccaac cgcgucaccu acgacgucgu cuuccacggc     2160

uaccucccca acgagggcga cuccaagaac ucccuccccu acggcaagau caacggcacc     2220

uacaagggca ccgagaagga gaagaucaag uucuccuccg agggcuccuu cgaccccgac     2280

ggcaagaucg ucuccuacga gugggacuuc ggcgacggca acaaguccaa cgaggagaac     2340

cccgagcacu ccuacgacaa ggucggcacc uacaccguca agcucaaggu caccgacgac     2400

aagggcgagu ccuccgucuc caccaccacc gccgagauca aggaccucuc cgagaacaag     2460

cuccccguca ucuacaugca cguccccaag uccggcgccc ucaaccagaa ggucgucuuc     2520

uacggcaagg gcaccuacga ccccgacggc uccaucgccg gcuaccagug ggacuucggc     2580

gacggcuccg acuucuccuc cgagcagaac cccucccacg ucuacaccaa gaagggcgag     2640

uacaccguca cccuccgcgu cauggacucc uccggccaga uguccgagaa gaccaugaag     2700

aucaagauca ccgaccccgu cuaccccauc ggcaccgaga aggagcccaa caacuccaag     2760

gagaccgccu ccggccccau cguccccggc auccccgucu ccggcaccau cgagaacacc     2820

uccgaccagg acuacuucua cuucgacguc aucacccccg gcgaggucaa gaucgacauc     2880

aacaagcucg gcuacggcgg cgccaccugg gucgucuacg acgagaacaa caacgccguc     2940

uccuacgcca ccgacgacgg ccagaaccuc uccggcaagu ucaaggccga caagcccggc     3000

cgcuacuaca uccaccucua cauguucaac ggcuccuaca ugcccuaccg caucaacauc     3060

gagggcuccg ucggccgcug aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  1582
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt2)

<400>  1582
gggagaaagc uuaccaugaa gugggucacc uucaucuccc uccucuuccu cuucuccucc       60

gccuacuccg uccagaacga guccaagcgc uacaccgucu ccuaccucaa gacccucaac      120

uacuacgacc ucgucgaccu ccucgucaag accgagaucg agaaccuccc cgaccucuuc      180

caguacuccu ccgacgccaa ggaguucuac ggcaacaaga cccgcauguc cuucaucaug      240

gacgagaucg gccgccgcgc cccccaguac accgagaucg accacaaggg cauccccacc      300

cucgucgagg ucguccgcgc cggcuucuac cucggcuucc acaacaagga gcucaacgag      360

aucaacaagc gcuccuucaa ggagcgcguc auccccucca uccucgccau ccagaagaac      420

cccaacuuca agcucggcac cgagguccag gacaagaucg ucuccgccac cggccuccuc      480

gccggcaacg agaccgcccc ccccgagguc gucaacaacu ucacccccau ccuccaggac      540

ugcaucaaga acaucgaccg cuacgcccuc gacgaccuca aguccaaggc ccucuucaac      600

guccucgccg cccccaccua cgacaucacc gaguaccucc gcgccaccaa ggagaagccc      660

gagaacaccc ccugguacgg caagaucgac ggcuucauca acgagcucaa gaagcucgcc      720

cucuacggca agaucaacga caacaacucc uggaucaucg acaacggcau cuaccacauc      780

gccccccucg gcaagcucca cuccaacaac aagaucggca ucgagacccu caccgagguc      840

augaaggucu accccuaccu cuccaugcag caccuccagu ccgccgacca gaucaagcgc      900

cacuacgacu ccaaggacgc cgagggcaac aagauccccc ucgacaaguu caagaaggag      960

ggcaaggaga aguacugccc caagaccuac accuucgacg acggcaaggu caucaucaag     1020

gccggcgccc gcgucgagga ggagaagguc aagcgccucu acugggccuc caaggagguc     1080

aacucccagu ucuuccgcgu cuacggcauc gacaagcccc ucgaggaggg caaccccgac     1140

gacauccuca ccauggucau cuacaacucc cccgaggagu acaagcucaa cuccguccuc     1200

uacggcuacg acaccaacaa cggcggcaug uacaucgagc ccgagggcac cuucuucacc     1260

uacgagcgcg aggcccagga guccaccuac acccucgagg agcucuuccg ccacgaguac     1320

acccacuacc uccagggccg cuacgccguc cccggccagu ggggccgcac caagcucuac     1380

gacaacgacc gccucaccug guacgaggag ggcggcgccg agcucuucgc cggcuccacc     1440

cgcaccuccg gcauccuccc ccgcaagucc aucgucucca acauccacaa caccacccgc     1500

aacaaccgcu acaagcucuc cgacaccguc cacuccaagu acggcgccuc cuucgaguuc     1560

uacaacuacg ccugcauguu cauggacuac auguacaaca aggacauggg cauccucaac     1620

aagcucaacg accucgccaa gaacaacgac gucgacggcu acgacaacua cauccgcgac     1680

cucuccucca acuacgcccu caacgacaag uaccaggacc acaugcagga gcgcaucgac     1740

aacuacgaga accucaccgu ccccuucguc gccgacgacu accucguccg ccacgccuac     1800

aagaacccca acgagaucua cuccgagauc uccgaggucg ccaagcucaa ggacgccaag     1860

uccgagguca agaaguccca guacuucucc accuucaccc uccgcggcuc cuacaccggc     1920

ggcgccucca agggcaagcu cgaggaccag aaggccauga acaaguucau cgacgacucc     1980

cucaagaagc ucgacaccua cuccuggucc ggcuacaaga cccucaccgc cuacuucacc     2040

aacuacaagg ucgacuccuc caaccgcguc accuacgacg ucgucuucca cggcuaccuc     2100

cccaacgagg gcgacuccaa gaacucccuc cccuacggca agaucaacgg caccuacaag     2160

ggcaccgaga aggagaagau caaguucucc uccgagggcu ccuucgaccc cgacggcaag     2220

aucgucuccu acgaguggga cuucggcgac ggcaacaagu ccaacgagga gaaccccgag     2280

cacuccuacg acaaggucgg caccuacacc gucaagcuca aggucaccga cgacaagggc     2340

gaguccuccg ucuccaccac caccgccgag aucaaggacc ucuccgagaa caagcucccc     2400

gucaucuaca ugcacguccc caaguccggc gcccucaacc agaaggucgu cuucuacggc     2460

aagggcaccu acgaccccga cggcuccauc gccggcuacc agugggacuu cggcgacggc     2520

uccgacuucu ccuccgagca gaaccccucc cacgucuaca ccaagaaggg cgaguacacc     2580

gucacccucc gcgucaugga cuccuccggc cagauguccg agaagaccau gaagaucaag     2640

aucaccgacc ccgucuaccc caucggcacc gagaaggagc ccaacaacuc caaggagacc     2700

gccuccggcc ccaucguccc cggcaucccc gucuccggca ccaucgagaa caccuccgac     2760

caggacuacu ucuacuucga cgucaucacc cccggcgagg ucaagaucga caucaacaag     2820

cucggcuacg gcggcgccac cugggucguc uacgacgaga acaacaacgc cgucuccuac     2880

gccaccgacg acggccagaa ccucuccggc aaguucaagg ccgacaagcc cggccgcuac     2940

uacauccacc ucuacauguu caacggcucc uacaugcccu accgcaucaa caucgagggc     3000

uccgucggcc gcugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1583
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt2)

<400>  1583
gggagaaagc uuaccaugaa gugggucacc uucaucuccc uccucuuccu cuucuccucc       60

gccuacucca ugaagcgcaa gugccucucc aagcgccuca ugcucgccau caccauggcc      120

accaucuuca ccgucaacuc cacccucccc aucuacgccg ccgucgacaa gaacaacgcc      180

accgccgccc gccgccgccg caagcgcguc cagaacgagu ccaagcgcua caccgucucc      240

uaccucaaga cccucaacua cuacgaccuc gucgaccucc ucgucaagac cgagaucgag      300

aaccuccccg accucuucca guacuccucc gacgccaagg aguucuacgg caacaagacc      360

cgcauguccu ucaucaugga cgagaucggc cgccgcgccc cccaguacac cgagaucgac      420

cacaagggca uccccacccu cgucgagguc guccgcgccg gcuucuaccu cggcuuccac      480

aacaaggagc ucaacgagau caacaagcgc uccuucaagg agcgcgucau ccccuccauc      540

cucgccaucc agaagaaccc caacuucaag cucggcaccg agguccagga caagaucguc      600

uccgccaccg gccuccucgc cggcaacgag accgcccccc ccgaggucgu caacaacuuc      660

acccccaucc uccaggacug caucaagaac aucgaccgcu acgcccucga cgaccucaag      720

uccaaggccc ucuucaacgu ccucgccgcc cccaccuacg acaucaccga guaccuccgc      780

gccaccaagg agaagcccga gaacaccccc ugguacggca agaucgacgg cuucaucaac      840

gagcucaaga agcucgcccu cuacggcaag aucaacgaca acaacuccug gaucaucgac      900

aacggcaucu accacaucgc cccccucggc aagcuccacu ccaacaacaa gaucggcauc      960

gagacccuca ccgaggucau gaaggucuac cccuaccucu ccaugcagca ccuccagucc     1020

gccgaccaga ucaagcgcca cuacgacucc aaggacgccg agggcaacaa gaucccccuc     1080

gacaaguuca agaaggaggg caaggagaag uacugcccca agaccuacac cuucgacgac     1140

ggcaagguca ucaucaaggc cggcgcccgc gucgaggagg agaaggucaa gcgccucuac     1200

ugggccucca aggaggucaa cucccaguuc uuccgcgucu acggcaucga caagccccuc     1260

gaggagggca accccgacga cauccucacc auggucaucu acaacucccc cgaggaguac     1320

aagcucaacu ccguccucua cggcuacgac accaacaacg gcggcaugua caucgagccc     1380

gagggcaccu ucuucaccua cgagcgcgag gcccaggagu ccaccuacac ccucgaggag     1440

cucuuccgcc acgaguacac ccacuaccuc cagggccgcu acgccguccc cggccagugg     1500

ggccgcacca agcucuacga caacgaccgc cucaccuggu acgaggaggg cggcgccgag     1560

cucuucgccg gcuccacccg caccuccggc auccuccccc gcaaguccau cgucuccaac     1620

auccacaaca ccacccgcaa caaccgcuac aagcucuccg acaccgucca cuccaaguac     1680

ggcgccuccu ucgaguucua caacuacgcc ugcauguuca uggacuacau guacaacaag     1740

gacaugggca uccucaacaa gcucaacgac cucgccaaga acaacgacgu cgacggcuac     1800

gacaacuaca uccgcgaccu cuccuccaac uacgcccuca acgacaagua ccaggaccac     1860

augcaggagc gcaucgacaa cuacgagaac cucaccgucc ccuucgucgc cgacgacuac     1920

cucguccgcc acgccuacaa gaaccccaac gagaucuacu ccgagaucuc cgaggucgcc     1980

aagcucaagg acgccaaguc cgaggucaag aagucccagu acuucuccac cuucacccuc     2040

cgcggcuccu acaccggcgg cgccuccaag ggcaagcucg aggaccagaa ggccaugaac     2100

aaguucaucg acgacucccu caagaagcuc gacaccuacu ccugguccgg cuacaagacc     2160

cucaccgccu acuucaccaa cuacaagguc gacuccucca accgcgucac cuacgacguc     2220

gucuuccacg gcuaccuccc caacgagggc gacuccaaga acucccuccc cuacggcaag     2280

aucaacggca ccuacaaggg caccgagaag gagaagauca aguucuccuc cgagggcucc     2340

uucgaccccg acggcaagau cgucuccuac gagugggacu ucggcgacgg caacaagucc     2400

aacgaggaga accccgagca cuccuacgac aaggucggca ccuacaccgu caagcucaag     2460

gucaccgacg acaagggcga guccuccguc uccaccacca ccgccgagau caaggaccuc     2520

uccgagaaca agcuccccgu caucuacaug cacgucccca aguccggcgc ccucaaccag     2580

aaggucgucu ucuacggcaa gggcaccuac gaccccgacg gcuccaucgc cggcuaccag     2640

ugggacuucg gcgacggcuc cgacuucucc uccgagcaga accccuccca cgucuacacc     2700

aagaagggcg aguacaccgu cacccuccgc gucauggacu ccuccggcca gauguccgag     2760

aagaccauga agaucaagau caccgacccc gucuacccca ucggcaccga gaaggagccc     2820

aacaacucca aggagaccgc cuccggcccc aucguccccg gcauccccgu cuccggcacc     2880

aucgagaaca ccuccgacca ggacuacuuc uacuucgacg ucaucacccc cggcgagguc     2940

aagaucgaca ucaacaagcu cggcuacggc ggcgccaccu gggucgucua cgacgagaac     3000

aacaacgccg ucuccuacgc caccgacgac ggccagaacc ucuccggcaa guucaaggcc     3060

gacaagcccg gccgcuacua cauccaccuc uacauguuca acggcuccua caugcccuac     3120

cgcaucaaca ucgagggcuc cgucggccgc ugaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  1584
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt2)

<400>  1584
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccuccucgg cgccgccuuc       60

gccaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc      120

cucacccccc ucaaguggua ccaguccauc cgcccccccu accccuccua cggcuacgag      180

cccaugggcg gcuggcucca ccaccagauc auccccgucc ucucccagca gcaccccccc      240

acccacaccc uccagcccca ccaccacauc cccgucgucc ccgcccagca gcccgucauc      300

ccccagcagc ccaugaugcc cguccccggc cagcacucca ugacccccau ccagcaccac      360

cagcccaacc uccccccccc cgcccagcag cccuaccagc cccagcccgu ccagccccag      420

ccccaccagc ccaugcagcc ccagcccccc guccacccca ugcagccccu ccccccccag      480

cccccccucc cccccauguu ccccaugcag ccccuccccc ccaugcuccc cgaccucacc      540

cucgaggccu ggcccuccac cgacaagacc aagcgcgagg aggucgacug aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  1585
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt2)

<400>  1585
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgagg uccucacccc ccucaagugg uaccagucca uccgcccccc cuaccccucc      120

uacggcuacg agcccauggg cggcugguga ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  1586
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt2)

<400>  1586
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgagg uccucacccc ccucaagugg uaccagucca uccgcccccc ccccaugcuc      120

cccgaccuca cccucgaggc cuggcccucc accgacaaga ccaagcgcga ggaggucgac      180

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  1587
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt2)

<400>  1587
gggagaaagc uuaccauggc cgucauggcc ccccgcaccc ucguccuccu ccucuccggc       60

gcccucgccc ucacccagac cugggccaug ccccuccccc cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga gguccucacc ccccucaagu gguaccaguc cauccgcccc      180

cccuaccccu ccuacggcua cgagcccaug ggcggcuggu gaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  1588
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt2)

<400>  1588
gggagaaagc uuaccauggc cgucauggcc ccccgcaccc ucguccuccu ccucuccggc       60

gcccucgccc ucacccagac cugggccaug ccccuccccc cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga gguccucacc ccccucaagu gguaccaguc cauccgcccc      180

ccccccaugc uccccgaccu cacccucgag gccuggcccu ccaccgacaa gaccaagcgc      240

gaggaggucg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  1589
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt2)

<400>  1589
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccucgucgg cgccgccuuc       60

gccaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc      120

cucacccccc ucaaguggua ccaguccaug auccgccccc ccuacuccuc cuacggcuac      180

gagcccaugg gcggcuggcu ccaccaccag aucauccccg ucgucuccca gcagcacccc      240

cucacccaca cccuccaguc ccaccaccac auccccgucg uccccgccca gcagccccgc      300

guccgccagc aggcccucau gcccgucccc ggccagcagu ccaugacccc cacccagcac      360

caccagccca accucccccu ccccgcccag cagcccuucc agccccagcc cguccagccc      420

cagccccacc agcccaugca gccccagccc cccguccagc ccaugcagcc ccuccucccc      480

cagccccccc ucccccccau guucccccuc cgcccccucc cccccauccu ccccgaccuc      540

caccucgagg ccuggcccgc caccgacaag accaagcagg aggaggucga cugaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  1590
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt2)

<400>  1590
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgagg uccucacccc ccucaagugg uaccagucca ugauccgccc ccccuacucc      120

uccuacggcu acgagcccau gggcggcugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1591
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt2)

<400>  1591
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgagg uccucacccc ccucaagugg uaccagucca ugauccgccc cccccccauc      120

cuccccgacc uccaccucga ggccuggccc gccaccgaca agaccaagca ggaggagguc      180

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1592
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt2)

<400>  1592
gggagaaagc uuaccauggc cgucauggcc ccccgcaccc ucguccuccu ccucuccggc       60

gcccucgccc ucacccagac cugggccaug ccccuccccc cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga gguccucacc ccccucaagu gguaccaguc caugauccgc      180

ccccccuacu ccuccuacgg cuacgagccc augggcggcu ggugaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1593
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt2)

<400>  1593
gggagaaagc uuaccauggc cgucauggcc ccccgcaccc ucguccuccu ccucuccggc       60

gcccucgccc ucacccagac cugggccaug ccccuccccc cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga gguccucacc ccccucaagu gguaccaguc caugauccgc      180

ccccccccca uccuccccga ccuccaccuc gaggccuggc ccgccaccga caagaccaag      240

caggaggagg ucgacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1594
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt2)

<400>  1594
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccuccucgg cgccgccuuc       60

uccaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc      120

cucacccccc ucaaguggua ccagaacaug auccgccacc ccuacaccuc cuacggcuac      180

gagcccaugg gcggcuggcu ccaccaccag aucauccccg ucgucuccca gcagaccccc      240

cagucccacg cccuccagcc ccaccaccac auccccaugg uccccgccca gcagcccggc      300

aucccccagc agcccaugau gccccucccc ggccagcacu ccaugacccc cacccagcac      360

caccagccca accucccccu ccccgcccag cagcccuucc agccccagcc cguccagccc      420

cagccccacc agccccucca gccccagucc cccaugcacc ccauccagcc ccuccucccc      480

cagccccccc ucccccccau guucuccaug cagucccucc uccccgaccu cccccucgag      540

gccuggcccg ccaccgacaa gaccaagcgc gaggaggucg acugaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1595
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt2)

<400>  1595
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgagg uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccuacacc      120

uccuacggcu acgagcccau gggcggcugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1596
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt2)

<400>  1596
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgagg uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccucccuc      120

cuccccgacc ucccccucga ggccuggccc gccaccgaca agaccaagcg cgaggagguc      180

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1597
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt2)

<400>  1597
gggagaaagc uuaccauggc cgucauggcc ccccgcaccc ucguccuccu ccucuccggc       60

gcccucgccc ucacccagac cugggccaug ccccuccccc cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga gguccucacc ccccucaagu gguaccagaa caugauccgc      180

caccccuaca ccuccuacgg cuacgagccc augggcggcu ggugaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1598
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt2)

<400>  1598
gggagaaagc uuaccauggc cgucauggcc ccccgcaccc ucguccuccu ccucuccggc       60

gcccucgccc ucacccagac cugggccaug ccccuccccc cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga gguccucacc ccccucaagu gguaccagaa caugauccgc      180

caccccuccc uccuccccga ccucccccuc gaggccuggc ccgccaccga caagaccaag      240

cgcgaggagg ucgacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1599
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt2)

<400>  1599
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccuccucgg cgccgccuuc       60

uccaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacauccgc      120

caccccuaca ccuccuacgg cuacgagccc augggcggcu ggcuccacca ccagaucauc      180

cccgucgucu cccagcagac cccccagucc cacgcccucc agccccacca ccacaucccc      240

augguccccg cccagcagcc cggcaucccc cagcagccca ugaugccccu ccccggccag      300

cacuccauga cccccaccca gcaccaccag cccaaccucc cccuccccgc ccagcagccc      360

uuccagcccc agcccgucca gccccagccc caccagcccc uccagcccca gucccccaug      420

caccccaucc agccccuccu cccccagccc ccccuccccc ccauguucuc caugcagucc      480

cuccuccccg accucccccu cgaggccugg cccgccaccg acaagaccaa gcgcgaggag      540

gucgacugag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  1600
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt2)

<400>  1600
gggagaaagc uuaccauggg caccuggauc uucuucgccu gccuccucgg cgccucccuc       60

gccaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc      120

cucacccccc ucaaguggua ccagaacaug auccgccacc ccuacaccuc cuacggcuac      180

gagcccaugg gcggcuggcu ccaccaccag aucauccccg ucgucuccca gcagaccccc      240

cagucccacg cccuccagcc ccaccaccac auccccaugg uccccgccca gcagcccggc      300

aucccccagc agcccaugau gccccucccc ggccagcacu ccaugacccc cacccagcac      360

caccagccca accucccccu ccccgcccag cagcccuucc agccccagcc cguccagccc      420

cagccccacc agccccucca gccccagucc cccaugcacc ccauccagcc ccuccucccc      480

cagccccccc ucccccccau guucuccaug cagucccucc uccccgaccu cccccucgag      540

gccuggcccg ccaccgacaa gaccaagcgc gaggaggucg acugaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1601
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt2)

<400>  1601
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccuccucgg cgccgccuuc       60

uccaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc      120

cucacccccc ucaaguggua ccagaacaug auccgccacc ccucccuccu ccccgaccuc      180

ccccucgagg ccuggcccgc caccgacaag accaagcgcg aggaggucga cugaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  1602
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt2)

<400>  1602
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccuccucgg cgccgccuuc       60

uccaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgaggac      120

cucuaccucg aggccauccg caucgaccgc accgccuucg uccucacccc ccucaagugg      180

uaccagaaca ugauccgcca ccccuacacc uccuacggcu acgagcccau gggcggcugg      240

cuccaccacc agaucauccc cgucgucucc cagcagaccc cccaguccca cgcccuccag      300

ccccaccacc acauccccau gguccccgcc cagcagcccg gcauccccca gcagcccaug      360

augccccucc ccggccagca cuccaugacc cccacccagc accaccagcc caaccucccc      420

cuccccgccc agcagcccuu ccagccccag cccguccagc cccagcccca ccagccccuc      480

cagccccagu cccccaugca ccccauccag ccccuccucc cccagccccc ccuccccccc      540

auguucucca ugcagucccu ccuccccgac cucccccucg aggccuggcc cgccaccgac      600

aagaccaagc gcgaggaggu cgacugagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  1603
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt2)

<400>  1603
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccuccucgg cgccgccuuc       60

uccaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc      120

cucacccccc ucaaguggua ccagaacaug auccgccacc ccacccccca gucccacgcc      180

cuccagcccc accaccacau ccccaugguc cccgcccagc agcccggcau cccccagcag      240

cccaugaugc cccuccccgg ccagcacucc augaccccca cccagcacca ccagcccaac      300

cucccccucc ccgcccagca gcccuuccag ccccagcccg uccagcccca gccccaccag      360

ccccuccagc cccagucccc caugcacccc auccagcccc uccuccccca gcccccccuc      420

ccccccaugu ucuccaugca gucccuccuc cccgaccucc cccucgaggc cuggcccgcc      480

accgacaaga ccaagcgcga ggaggucgac ugaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  1604
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt2)

<400>  1604
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgagg uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccuacacc      120

uccuacggcu acgagcccau gggcggcugg cuccaccacc agaucauccc cgucgucucc      180

cagcagaccc cccaguccca cgcccuccag ccccaccacc acauccccau gguccccgcc      240

cagcagcccg gcauccccca gcagcccaug augccccucc ccggccagca cuccaugacc      300

cccacccagc accaccagcc caaccucccc cuccccgccc agcagcccuu ccagccccag      360

cccguccagc cccagcccca ccagccccuc cagccccagu cccccaugca ccccauccag      420

ccccuccucc cccagccccc ccuccccccc auguucucca ugcagucccu ccuccccgac      480

cucccccucg aggccuggcc cgccaccgac aagaccaagc gcgaggaggu cgacugagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  1605
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt2)

<400>  1605
gggagaaagc uuaccaugcc cggcgucgcc cgccuccccc uccuccucgg ccuccuccuc       60

cucccccgcc ccggccgccc ccucgaccuc gccgacuaca ccuacgaccu cgccgaggag      120

gacgacuccg agccccucaa cuacaaggac cccugcaagg ccgccgccuu ccucggcgac      180

aucgcccucg acgaggagga ccuccgcgcc uuccaggucc agcaggccgu cgaccuccgc      240

cgccacaccg cccgcaaguc cuccaucaag gccgccgucc ccggcaacac cuccaccccc      300

uccugccagu ccaccaacgg ccagccccag cgcggcgccu gcggccgcug gcgcggccgc      360

ucccgcuccc gccgcgccgc caccucccgc cccgagcgcg ucuggcccga cggcgucauc      420

cccuucguca ucggcggcaa cuucaccggc ucccagcgcg ccgucuuccg ccaggccaug      480

cgccacuggg agaagcacac cugcgucacc uuccucgagc gcaccgacga ggacuccuac      540

aucgucuuca ccuaccgccc cugcggcugc ugcuccuacg ucggccgccg cggcggcggc      600

ccccaggcca ucuccaucgg caagaacugc gacaaguucg gcaucgucgu ccacgagcuc      660

ggccacgucg ucggcuucug gcacgagcac acccgccccg accgcgaccg ccacgucucc      720

aucguccgcg agaacaucca gcccggccag gaguacaacu uccucaagau ggagccccag      780

gaggucgagu cccucggcga gaccuacgac uucgacucca ucaugcacua cgcccgcaac      840

accuucuccc gcggcaucuu ccucgacacc aucgucccca aguacgaggu caacggcguc      900

aagcccccca ucggccagcg cacccgccuc uccaagggcg acaucgccca ggcccgcaag      960

cucuacaagu gccccgccug cggcgagacc cuccaggacu ccaccggcaa cuucuccucc     1020

cccgaguacc ccaacggcua cuccgcccac augcacugcg ucuggcgcau cuccgucacc     1080

cccggcgaga agaucauccu caacuucacc ucccucgacc ucuaccgcuc ccgccucugc     1140

ugguacgacu acgucgaggu ccgcgacggc uucuggcgca aggccccccu ccgcggccgc     1200

uucugcggcu ccaagcuccc cgagcccauc gucuccaccg acucccgccu cugggucgag     1260

uuccgcuccu ccuccaacug ggucggcaag ggcuucuucg ccgucuacga ggccaucugc     1320

ggcggcgacg ucaagaagga cuacggccac auccaguccc ccaacuaccc cgacgacuac     1380

cgccccucca aggucugcau cuggcgcauc caggucuccg agggcuucca cgucggccuc     1440

accuuccagu ccuucgagau cgagcgccac gacuccugcg ccuacgacua ccucgagguc     1500

cgcgacggcc acuccgaguc cuccacccuc aucggccgcu acugcggcua cgagaagccc     1560

gacgacauca aguccaccuc cucccgccuc uggcucaagu ucgucuccga cggcuccauc     1620

aacaaggccg gcuucgccgu caacuucuuc aaggaggucg acgagugcuc ccgccccaac     1680

cgcggcggcu gcgagcagcg cugccucaac acccucggcu ccuacaagug cuccugcgac     1740

cccggcuacg agcucgcccc cgacaagcgc cgcugcgagg ccgccugcgg cggcuuccuc     1800

accaagcuca acggcuccau caccuccccc ggcuggccca aggaguaccc ccccaacaag     1860

aacugcaucu ggcagcucgu cgcccccacc caguaccgca ucucccucca guucgacuuc     1920

uucgagaccg agggcaacga cgucugcaag uacgacuucg ucgagguccg cuccggccuc     1980

accgccgacu ccaagcucca cggcaaguuc ugcggcuccg agaagcccga ggucaucacc     2040

ucccaguaca acaacaugcg cgucgaguuc aaguccgaca acaccgucuc caagaagggc     2100

uucaaggccc acuucuucuc cgacaaggac gagugcucca aggacaacgg cggcugccag     2160

caggacugcg ucaacaccuu cggcuccuac gagugccagu gccgcuccgg cuucguccuc     2220

cacgacaaca agcacgacug caaggaggcc ggcugcgacc acaaggucac cuccaccucc     2280

ggcaccauca ccucccccaa cuggcccgac aaguaccccu ccaagaagga gugcaccugg     2340

gccaucuccu ccacccccgg ccaccgcguc aagcucaccu ucauggagau ggacaucgag     2400

ucccagcccg agugcgccua cgaccaccuc gaggucuucg acggccgcga cgccaaggcc     2460

cccguccucg gccgcuucug cggcuccaag aagcccgagc ccguccucgc caccggcucc     2520

cgcauguucc uccgcuucua cuccgacaac uccguccagc gcaagggcuu ccaggccucc     2580

cacgccaccg agugcggcgg ccagguccgc gccgacguca agaccaagga ccucuacucc     2640

cacgcccagu ucggcgacaa caacuacccc ggcggcgucg acugcgagug ggucaucguc     2700

gccgaggagg gcuacggcgu cgagcucguc uuccagaccu ucgaggucga ggaggagacc     2760

gacugcggcu acgacuacau ggagcucuuc gacggcuacg acuccaccgc cccccgccuc     2820

ggccgcuacu gcggcuccgg cccccccgag gaggucuacu ccgccggcga cuccguccuc     2880

gucaaguucc acuccgacga caccaucacc aagaagggcu uccaccuccg cuacaccucc     2940

accaaguucc aggacacccu ccacucccgc aagugaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  1606
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt2)

<400>  1606
gggagaaagc uuaccauggu cgccggcacc cgcugccucc ucgcccuccu ccucccccag       60

guccuccucg gcggcgccgc cggccucguc cccgagcucg gccgccgcaa guucgccgcc      120

gccuccuccg gccgccccuc cucccagccc uccgacgagg uccucuccga guucgagcuc      180

cgccuccucu ccauguucgg ccucaagcag cgccccaccc ccucccgcga cgccgucguc      240

ccccccuaca ugcucgaccu cuaccgccgc cacuccggcc agcccggcuc ccccgccccc      300

gaccaccgcc ucgagcgcgc cgccucccgc gccaacaccg uccgcuccuu ccaccacgag      360

gagucccucg aggagcuccc cgagaccucc ggcaagacca cccgccgcuu cuucuucaac      420

cucuccucca uccccaccga ggaguucauc accuccgccg agcuccaggu cuuccgcgag      480

cagaugcagg acgcccucgg caacaacucc uccuuccacc accgcaucaa caucuacgag      540

aucaucaagc ccgccaccgc caacuccaag uuccccguca cccgccuccu cgacacccgc      600

cucgucaacc agaacgccuc ccgcugggag uccuucgacg ucacccccgc cgucaugcgc      660

uggaccgccc agggccacgc caaccacggc uucgucgucg aggucgccca ccucgaggag      720

aagcagggcg ucuccaagcg ccacguccgc aucucccgcu cccuccacca ggacgagcac      780

uccugguccc agauccgccc ccuccucguc accuucggcc acgacggcaa gggccacccc      840

cuccacaagc gcgagaagcg ccaggccaag cacaagcagc gcaagcgccu caaguccucc      900

ugcaagcgcc acccccucua cgucgacuuc uccgacgucg gcuggaacga cuggaucguc      960

gccccccccg gcuaccacgc cuucuacugc cacggcgagu gccccuuccc ccucgccgac     1020

caccucaacu ccaccaacca cgccaucguc cagacccucg ucaacuccgu caacuccaag     1080

auccccaagg ccugcugcgu ccccaccgag cucuccgcca ucuccaugcu cuaccucgac     1140

gagaacgaga aggucguccu caagaacuac caggacaugg ucgucgaggg cugcggcugc     1200

cgcugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  1607
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt2)

<400>  1607
gggagaaagc uuaccaugau ccccggcaac cgcaugcuca uggucguccu ccucugccag       60

guccuccucg gcggcgccuc ccacgccucc cucauccccg agaccggcaa gaagaagguc      120

gccgagaucc agggccacgc cggcggccgc cgcuccggcc agucccacga gcuccuccgc      180

gacuucgagg ccacccuccu ccagauguuc ggccuccgcc gccgccccca gcccuccaag      240

uccgccguca uccccgacua caugcgcgac cucuaccgcc uccaguccgg cgaggaggag      300

gaggagcaga uccacuccac cggccucgag uaccccgagc gccccgccuc ccgcgccaac      360

accguccgcu ccuuccacca cgaggagcac cucgagaaca uccccggcac cuccgagaac      420

uccgccuucc gcuuccucuu caaccucucc uccauccccg agaacgaggu caucuccucc      480

gccgagcucc gccucuuccg cgagcagguc gaccagggcc ccgacuggga gcgcggcuuc      540

caccgcauca acaucuacga ggucaugaag ccccccgccg aggucguccc cggccaccuc      600

aucacccgcc uccucgacac ccgccucguc caccacaacg ucacccgcug ggagaccuuc      660

gacgucuccc ccgccguccu ccgcuggacc cgcgagaagc agcccaacua cggccucgcc      720

aucgagguca cccaccucca ccagacccgc acccaccagg gccagcacgu ccgcaucucc      780

cgcucccucc cccagggcuc cggcaacugg gcccagcucc gcccccuccu cgucaccuuc      840

ggccacgacg gccgcggcca cgcccucacc cgccgccgcc gcgccaagcg cucccccaag      900

caccacuccc agcgcgcccg caagaagaac aagaacugcc gccgccacuc ccucuacguc      960

gacuucuccg acgucggcug gaacgacugg aucgucgccc cccccggcua ccaggccuuc     1020

uacugccacg gcgacugccc cuucccccuc gccgaccacc ucaacuccac caaccacgcc     1080

aucguccaga cccucgucaa cuccgucaac uccuccaucc ccaaggccug cugcgucccc     1140

accgagcucu ccgccaucuc caugcucuac cucgacgagu acgacaaggu cguccucaag     1200

aacuaccagg agauggucgu cgagggcugc ggcugccgcu gaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  1608
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt2)

<400>  1608
gggagaaagc uuaccaugcc cggccucggc cgccgcgccc aguggcucug cugguggugg       60

ggccuccucu gcuccugcug cggccccccc ccccuccgcc ccccccuccc cgccgccgcc      120

gccgccgccg ccggcggcca gcuccucggc gacggcggcu cccccggccg caccgagcag      180

cccccccccu ccccccaguc cuccuccggc uuccucuacc gccgccucaa gacccaggag      240

aagcgcgaga ugcagaagga gauccucucc guccucggcc ucccccaccg cccccgcccc      300

cuccacggcc uccagcagcc ccagcccccc gcccuccgcc agcaggagga gcagcagcag      360

cagcagcagc ucccccgcgg cgagcccccc cccggccgcc ucaaguccgc cccccucuuc      420

augcucgacc ucuacaacgc ccucuccgcc gacaacgacg aggacggcgc cuccgagggc      480

gagcgccagc aguccuggcc ccacgaggcc gccuccuccu cccagcgccg ccagcccccc      540

cccggcgccg cccacccccu caaccgcaag ucccuccucg cccccggcuc cggcuccggc      600

ggcgccuccc cccucaccuc cgcccaggac uccgccuucc ucaacgacgc cgacaugguc      660

auguccuucg ucaaccucgu cgaguacgac aaggaguucu ccccccgcca gcgccaccac      720

aaggaguuca aguucaaccu cucccagauc cccgagggcg aggucgucac cgccgccgag      780

uuccgcaucu acaaggacug cgucaugggc uccuucaaga accagaccuu ccucaucucc      840

aucuaccagg uccuccagga gcaccagcac cgcgacuccg accucuuccu ccucgacacc      900

cgcgucgucu gggccuccga ggagggcugg cucgaguucg acaucaccgc caccuccaac      960

cucugggucg ucacccccca gcacaacaug ggccuccagc ucuccgucgu cacccgcgac     1020

ggcguccacg uccacccccg cgccgccggc cucgucggcc gcgacggccc cuacgacaag     1080

cagcccuuca uggucgccuu cuucaagguc uccgaggucc acguccgcac cacccgcucc     1140

gccuccuccc gccgccgcca gcagucccgc aaccgcucca cccaguccca ggacgucgcc     1200

cgcgucuccu ccgccuccga cuacaacucc uccgagcuca agaccgccug ccgcaagcac     1260

gagcucuacg ucuccuucca ggaccucggc uggcaggacu ggaucaucgc ccccaagggc     1320

uacgccgcca acuacugcga cggcgagugc uccuuccccc ucaacgccca caugaacgcc     1380

accaaccacg ccaucgucca gacccucguc caccucauga accccgagua cguccccaag     1440

cccugcugcg cccccaccaa gcucaacgcc aucuccgucc ucuacuucga cgacaacucc     1500

aacgucaucc ucaagaagua ccgcaacaug gucguccgcg ccugcggcug ccacugagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  1609
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt2)

<400>  1609
gggagaaagc uuaccaugca cguccgcucc cuccgcgccg ccgcccccca cuccuucguc       60

gcccucuggg ccccccucuu ccuccuccgc uccgcccucg ccgacuucuc ccucgacaac      120

gagguccacu ccuccuucau ccaccgccgc cuccgcuccc aggagcgccg cgagaugcag      180

cgcgagaucc ucuccauccu cggccucccc caccgccccc gcccccaccu ccagggcaag      240

cacaacuccg cccccauguu caugcucgac cucuacaacg ccauggccgu cgaggagggc      300

ggcggccccg gcggccaggg cuucuccuac cccuacaagg ccgucuucuc cacccagggc      360

cccccccucg ccucccucca ggacucccac uuccucaccg acgccgacau ggucaugucc      420

uucgucaacc ucgucgagca cgacaaggag uucuuccacc cccgcuacca ccaccgcgag      480

uuccgcuucg accucuccaa gauccccgag ggcgaggccg ucaccgccgc cgaguuccgc      540

aucuacaagg acuacauccg cgagcgcuuc gacaacgaga ccuuccgcau cuccgucuac      600

cagguccucc aggagcaccu cggccgcgag uccgaccucu uccuccucga cucccgcacc      660

cucugggccu ccgaggaggg cuggcucguc uucgacauca ccgccaccuc caaccacugg      720

gucgucaacc cccgccacaa ccucggccuc cagcucuccg ucgagacccu cgacggccag      780

uccaucaacc ccaagcucgc cggccucauc ggccgccacg gcccccagaa caagcagccc      840

uucauggucg ccuucuucaa ggccaccgag guccacuucc gcuccauccg cuccaccggc      900

uccaagcagc gcucccagaa ccgcuccaag acccccaaga accaggaggc ccuccgcaug      960

gccaacgucg ccgagaacuc cuccuccgac cagcgccagg ccugcaagaa gcacgagcuc     1020

uacgucuccu uccgcgaccu cggcuggcag gacuggauca ucgcccccga gggcuacgcc     1080

gccuacuacu gcgagggcga gugcgccuuc ccccucaacu ccuacaugaa cgccaccaac     1140

cacgccaucg uccagacccu cguccacuuc aucaaccccg agaccguccc caagcccugc     1200

ugcgccccca cccagcucaa cgccaucucc guccucuacu ucgacgacuc cuccaacguc     1260

auccucaaga aguaccgcaa cauggucguc cgcgccugcg gcugccacug aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  1610
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt2)

<400>  1610
gggagaaagc uuaccaugaa ggccuccgcc gcccuccucu gccuccuccu caccgccgcc       60

gccuucuccc cccagggccu cgcccagccc gucggcauca acaccuccac caccugcugc      120

uaccgcuuca ucaacaagaa gauccccaag cagcgccucg aguccuaccg ccgcaccacc      180

uccucccacu gcccccgcga ggccgucauc uucaagacca agcucgacaa ggagaucugc      240

gccgacccca cccagaagug gguccaggac uucaugaagc accucgacaa gaagacccag      300

acccccaagc ucugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  1611
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt2)

<400>  1611
gggagaaagc uuaccaugcu ccucacccuc aucauccucc uccccgucgu cuccaaguuc       60

uccuucgucu cccucuccgc cccccagcac ugguccugcc ccgagggcac ccucgccggc      120

aacggcaacu ccaccugcgu cggccccgcc cccuuccuca ucuucuccca cggcaacucc      180

aucuuccgca ucgacaccga gggcaccaac uacgagcagc ucgucgucga cgccggcguc      240

uccgucauca uggacuucca cuacaacgag aagcgcaucu acugggucga ccucgagcgc      300

cagcuccucc agcgcgucuu ccucaacggc ucccgccagg agcgcgucug caacaucgag      360

aagaacgucu ccggcauggc caucaacugg aucaacgagg aggucaucug guccaaccag      420

caggagggca ucaucaccgu caccgacaug aagggcaaca acucccacau ccuccucucc      480

gcccucaagu accccgccaa cgucgccguc gaccccgucg agcgcuucau cuucuggucc      540

uccgaggucg ccggcucccu cuaccgcgcc gaccucgacg gcgucggcgu caaggcccuc      600

cucgagaccu ccgagaagau caccgccguc ucccucgacg uccucgacaa gcgccucuuc      660

uggauccagu acaaccgcga gggcuccaac ucccucaucu gcuccugcga cuacgacggc      720

ggcuccgucc acaucuccaa gcaccccacc cagcacaacc ucuucgccau gucccucuuc      780

ggcgaccgca ucuucuacuc caccuggaag augaagacca ucuggaucgc caacaagcac      840

accggcaagg acaugguccg caucaaccuc cacuccuccu ucgucccccu cggcgagcuc      900

aaggucgucc acccccucgc ccagcccaag gccgaggacg acaccuggga gcccgagcag      960

aagcucugca agcuccgcaa gggcaacugc uccuccaccg ucugcggcca ggaccuccag     1020

ucccaccucu gcaugugcgc cgagggcuac gcccucuccc gcgaccgcaa guacugcgag     1080

gacgucaacg agugcgccuu cuggaaccac ggcugcaccc ucggcugcaa gaacaccccc     1140

ggcuccuacu acugcaccug ccccgucggc uucguccucc uccccgacgg caagcgcugc     1200

caccagcucg ucuccugccc ccgcaacguc uccgagugcu cccacgacug cguccucacc     1260

uccgagggcc cccucugcuu cugccccgag ggcuccgucc ucgagcgcga cggcaagacc     1320

ugcuccggcu gcuccucccc cgacaacggc ggcugcuccc agcucugcgu cccccucucc     1380

cccgucuccu gggagugcga cugcuucccc ggcuacgacc uccagcucga cgagaagucc     1440

ugcgccgccu ccggccccca gcccuuccuc cucuucgcca acucccagga cauccgccac     1500

augcacuucg acggcaccga cuacggcacc cuccucuccc agcagauggg cauggucuac     1560

gcccucgacc acgaccccgu cgagaacaag aucuacuucg cccacaccgc ccucaagugg     1620

aucgagcgcg ccaacaugga cggcucccag cgcgagcgcc ucaucgagga gggcgucgac     1680

guccccgagg gccucgccgu cgacuggauc ggccgccgcu ucuacuggac cgaccgcggc     1740

aagucccuca ucggccgcuc cgaccucaac ggcaagcgcu ccaagaucau caccaaggag     1800

aacaucuccc agccccgcgg caucgccguc caccccaugg ccaagcgccu cuucuggacc     1860

gacaccggca ucaacccccg caucgagucc uccucccucc agggccucgg ccgccucguc     1920

aucgccuccu ccgaccucau cuggcccucc ggcaucacca ucgacuuccu caccgacaag     1980

cucuacuggu gcgacgccaa gcaguccguc aucgagaugg ccaaccucga cggcuccaag     2040

cgccgccgcc ucacccagaa cgacgucggc caccccuucg ccgucgccgu cuucgaggac     2100

uacgucuggu ucuccgacug ggccaugccc uccgucaugc gcgucaacaa gcgcaccggc     2160

aaggaccgcg uccgccucca gggcuccaug cucaagcccu ccucccucgu cgucguccac     2220

ccccucgcca agcccggcgc cgaccccugc cucuaccaga acggcggcug cgagcacauc     2280

ugcaagaagc gccucggcac cgccuggugc uccugccgcg agggcuucau gaaggccucc     2340

gacggcaaga ccugccucgc ccucgacggc caccagcucc ucgccggcgg cgaggucgac     2400

cucaagaacc aggucacccc ccucgacauc cucuccaaga cccgcgucuc cgaggacaac     2460

aucaccgagu cccagcacau gcucgucgcc gagaucaugg ucuccgacca ggacgacugc     2520

gcccccgucg gcugcuccau guacgcccgc ugcaucuccg agggcgagga cgccaccugc     2580

cagugccuca agggcuucgc cggcgacggc aagcucugcu ccgacaucga cgagugcgag     2640

augggcgucc ccgucugccc ccccgccucc uccaagugca ucaacaccga gggcggcuac     2700

gucugccgcu gcuccgaggg cuaccagggc gacggcaucc acugccucga caucgacgag     2760

ugccagcucg gcgagcacuc cugcggcgag aacgccuccu gcaccaacac cgagggcggc     2820

uacaccugca ugugcgccgg ccgccucucc gagcccggcc ucaucugccc cgacuccacc     2880

cccccccccc accuccgcga ggacgaccac cacuacuccg uccgcaacuc cgacuccgag     2940

ugcccccucu cccacgacgg cuacugccuc cacgacggcg ucugcaugua caucgaggcc     3000

cucgacaagu acgccugcaa cugcgucguc ggcuacaucg gcgagcgcug ccaguaccgc     3060

gaccucaagu ggugggagcu ccgccacgcc ggccacggcc agcagcagaa ggucaucguc     3120

gucgccgucu gcgucgucgu ccucgucaug cuccuccucc ucucccucug gggcgcccac     3180

uacuaccgca cccagaagcu ccucuccaag aaccccaaga accccuacga ggaguccucc     3240

cgcgacgucc gcucccgccg ccccgccgac accgaggacg gcauguccuc cugcccccag     3300

cccugguucg ucgucaucaa ggagcaccag gaccucaaga acggcggcca gcccgucgcc     3360

ggcgaggacg gccaggccgc cgacggcucc augcagccca ccuccuggcg ccaggagccc     3420

cagcucugcg gcaugggcac cgagcagggc ugcuggaucc ccgucuccuc cgacaagggc     3480

uccugccccc aggucaugga gcgcuccuuc cacaugcccu ccuacggcac ccagacccuc     3540

gagggcggcg ucgagaagcc ccacucccuc cucuccgcca acccccucug gcagcagcgc     3600

gcccucgacc ccccccacca gauggagcuc acccagugag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  1612
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt2)

<400>  1612
gggagaaagc uuaccaugac cgccggccgc cgcauggaga ugcucugcgc cggccgcguc       60

cccgcccucc uccucugccu cggcuuccac cuccuccagg ccguccucuc caccaccguc      120

auccccuccu gcauccccgg cgaguccucc gacaacugca ccgcccucgu ccagaccgag      180

gacaaccccc gcgucgccca ggucuccauc accaagugcu ccuccgacau gaacggcuac      240

ugccuccacg gccagugcau cuaccucguc gacauguccc agaacuacug ccgcugcgag      300

gucggcuaca ccggcguccg cugcgagcac uucuuccuca ccguccacca gccccucucc      360

aaggaguacg ucgcccucac cgucauccuc aucauccucu uccucaucac cgucgucggc      420

uccaccuacu acuucugccg cugguaccgc aaccgcaagu ccaaggagcc caagaaggag      480

uacgagcgcg ucaccuccgg cgaccccgag cucccccagg ucugaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  1613
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt2)

<400>  1613
gggagaaagc uuaccauggc cgagggcgag aucaccaccu ucaccgcccu caccgagaag       60

uucaaccucc cccccggcaa cuacaagaag cccaagcucc ucuacugcuc caacggcggc      120

cacuuccucc gcauccuccc cgacggcacc gucgacggca cccgcgaccg cuccgaccag      180

cacauccagc uccagcucuc cgccgagucc gucggcgagg ucuacaucaa guccaccgag      240

accggccagu accucgccau ggacaccgac ggccuccucu acggcuccca gacccccaac      300

gaggagugcc ucuuccucga gcgccucgag gagaaccacu acaacaccua caucuccaag      360

aagcacgccg agaagaacug guucgucggc cucaagaaga acggcuccug caagcgcggc      420

ccccgcaccc acuacggcca gaaggccauc cucuuccucc cccuccccgu cuccuccgac      480

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  1614
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt2)

<400>  1614
gggagaaagc uuaccauggu cggcgucggc ggcggcgacg ucgaggacgu caccccccgc       60

cccggcggcu gccagaucuc cggccgcggc gcccgcggcu gcaacggcau ccccggcgcc      120

gccgccuggg aggccgcccu cccccgccgc cgcccccgcc gccaccccuc cgucaacccc      180

cgcucccgcg ccgccggcuc cccccgcacc cgcggccgcc gcaccgagga gcgccccucc      240

ggcucccgcc ucggcgaccg cggccgcggc cgcgcccucc ccggcggccg ccucggcggc      300

cgcggccgcg gccgcgcccc cgagcgcguc ggcggccgcg gccgcggccg cggcaccgcc      360

gccccccgcg ccgcccccgc cgcccgcggc ucccgccccg gccccgccgg caccauggcc      420

gccggcucca ucaccacccu ccccgcccuc cccgaggacg gcggcuccgg cgccuucccc      480

cccggccacu ucaaggaccc caagcgccuc uacugcaaga acggcggcuu cuuccuccgc      540

auccaccccg acggccgcgu cgacggcguc cgcgagaagu ccgaccccca caucaagcuc      600

cagcuccagg ccgaggagcg cggcgucguc uccaucaagg gcgucugcgc caaccgcuac      660

cucgccauga aggaggacgg ccgccuccuc gccuccaagu gcgucaccga cgagugcuuc      720

uucuucgagc gccucgaguc caacaacuac aacaccuacc gcucccgcaa guacaccucc      780

ugguacgucg cccucaagcg caccggccag uacaagcucg gcuccaagac cggccccggc      840

cagaaggcca uccucuuccu ccccaugucc gccaaguccu gaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  1615
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt2)

<400>  1615
gggagaaagc uuaccaugca caaguggauc cucaccugga uccuccccac ccuccucuac       60

cgcuccugcu uccacaucau cugccucguc ggcaccaucu cccucgccug caacgacaug      120

acccccgagc agauggccac caacgucaac ugcuccuccc ccgagcgcca cacccgcucc      180

uacgacuaca uggagggcgg cgacauccgc guccgccgcc ucuucugccg cacccagugg      240

uaccuccgca ucgacaagcg cggcaagguc aagggcaccc aggagaugaa gaacaacuac      300

aacaucaugg agauccgcac cgucgccguc ggcaucgucg ccaucaaggg cgucgagucc      360

gaguucuacc ucgccaugaa caaggagggc aagcucuacg ccaagaagga gugcaacgag      420

gacugcaacu ucaaggagcu cauccucgag aaccacuaca acaccuacgc cuccgccaag      480

uggacccaca acggcggcga gauguucguc gcccucaacc agaagggcau ccccguccgc      540

ggcaagaaga ccaagaagga gcagaagacc gcccacuucc uccccauggc caucaccuga      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  1616
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt2)

<400>  1616
gggagaaagc uuaccaugaa gcuccucccc uccgucgucc ucaagcucuu ccucgccgcc       60

guccucuccg cccucgucac cggcgagucc cucgagcgcc uccgccgcgg ccucgccgcc      120

ggcaccucca accccgaccc ccccaccguc uccaccgacc agcuccuccc ccucggcggc      180

ggccgcgacc gcaagguccg cgaccuccag gaggccgacc ucgaccuccu ccgcgucacc      240

cucuccucca agccccaggc ccucgccacc cccaacaagg aggagcacgg caagcgcaag      300

aagaagggca agggccucgg caagaagcgc gaccccugcc uccgcaagua caaggacuuc      360

ugcauccacg gcgagugcaa guacgucaag gagcuccgcg cccccuccug caucugccac      420

cccggcuacc acggcgagcg cugccacggc cucucccucc ccgucgagaa ccgccucuac      480

accuacgacc acaccaccau ccucgccguc gucgccgucg uccucuccuc cgucugccuc      540

cucgucaucg ucggccuccu cauguuccgc uaccaccgcc gcggcggcua cgacgucgag      600

aacgaggaga aggucaagcu cggcaugacc aacucccacu gaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  1617
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt2)

<400>  1617
gggagaaagc uuaccaugug ggucaccaag cuccuccccg cccuccuccu ccagcacguc       60

cuccuccacc uccuccuccu ccccaucgcc auccccuacg ccgagggcca gcgcaagcgc      120

cgcaacacca uccacgaguu caagaagucc gccaagacca cccucaucaa gaucgacccc      180

gcccucaaga ucaagaccaa gaaggucaac accgccgacc agugcgccaa ccgcugcacc      240

cgcaacaagg gccuccccuu caccugcaag gccuucgucu ucgacaaggc ccgcaagcag      300

ugccucuggu uccccuucaa cuccaugucc uccggcguca agaaggaguu cggccacgag      360

uucgaccucu acgagaacaa ggacuacauc cgcaacugca ucaucggcaa gggccgcucc      420

uacaagggca ccgucuccau caccaagucc ggcaucaagu gccagcccug guccuccaug      480

aucccccacg agcacuccuu ccuccccucc uccuaccgcg gcaaggaccu ccaggagaac      540

uacugccgca acccccgcgg cgaggagggc ggccccuggu gcuucaccuc caaccccgag      600

guccgcuacg aggucugcga caucccccag ugcuccgagg ucgagugcau gaccugcaac      660

ggcgaguccu accgcggccu cauggaccac accgaguccg gcaagaucug ccagcgcugg      720

gaccaccaga ccccccaccg ccacaaguuc cuccccgagc gcuaccccga caagggcuuc      780

gacgacaacu acugccgcaa ccccgacggc cagccccgcc ccuggugcua cacccucgac      840

ccccacaccc gcugggagua cugcgccauc aagaccugcg ccgacaacac caugaacgac      900

accgacgucc cccucgagac caccgagugc auccagggcc agggcgaggg cuaccgcggc      960

accgucaaca ccaucuggaa cggcaucccc ugccagcgcu gggacuccca guacccccac     1020

gagcacgaca ugacccccga gaacuucaag ugcaaggacc uccgcgagaa cuacugccgc     1080

aaccccgacg gcuccgaguc ccccuggugc uucaccaccg accccaacau ccgcgucggc     1140

uacugcuccc agauccccaa cugcgacaug ucccacggcc aggacugcua ccgcggcaac     1200

ggcaagaacu acaugggcaa ccucucccag acccgcuccg gccucaccug cuccaugugg     1260

gacaagaaca uggaggaccu ccaccgccac aucuucuggg agcccgacgc cuccaagcuc     1320

aacgagaacu acugccgcaa ccccgacgac gacgcccacg gccccuggug cuacaccggc     1380

aacccccuca uccccuggga cuacugcccc aucucccgcu gcgagggcga caccaccccc     1440

accaucguca accucgacca ccccgucauc uccugcgcca agaccaagca gcuccgcguc     1500

gucaacggca uccccacccg caccaacauc ggcuggaugg ucucccuccg cuaccgcaac     1560

aagcacaucu gcggcggcuc ccucaucaag gaguccuggg uccucaccgc ccgccagugc     1620

uuccccuccc gcgaccucaa ggacuacgag gccuggcucg gcauccacga cguccacggc     1680

cgcggcgacg agaagugcaa gcagguccuc aacgucuccc agcucgucua cggccccgag     1740

ggcuccgacc ucguccucau gaagcucgcc cgccccgccg uccucgacga cuucgucucc     1800

accaucgacc uccccaacua cggcugcacc auccccgaga agaccuccug cuccgucuac     1860

ggcuggggcu acaccggccu caucaacuac gacggccucc uccgcgucgc ccaccucuac     1920

aucaugggca acgagaagug cucccagcac caccgcggca aggucacccu caacgagucc     1980

gagaucugcg ccggcgccga gaagaucggc uccggccccu gcgagggcga cuacggcggc     2040

ccccucgucu gcgagcagca caagaugcgc augguccucg gcgucaucgu ccccggccgc     2100

ggcugcgcca uccccaaccg ccccggcauc uucguccgcg ucgccuacua cgccaagugg     2160

auccacaaga ucauccucac cuacaagguc ccccaguccu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  1618
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt2)

<400>  1618
gggagaaagc uuaccauggc caaggccgcc gccaucggca ucgaccucgg caccaccuac       60

uccugcgucg gcgucuucca gcacggcaag gucgagauca ucgccaacga ccagggcaac      120

cgcaccaccc ccuccuacgu cgccuucacc gacaccgagc gccucaucgg cgacgccgcc      180

aagaaccagg ucgcccucaa cccccagaac accgucuucg acgccaagcg ccucaucggc      240

cgcaaguucg gcgaccccgu cguccagucc gacaugaagc acuggcccuu ccaggucauc      300

aacgacggcg acaagcccaa gguccagguc uccuacaagg gcgagaccaa ggccuucuac      360

cccgaggaga ucuccuccau gguccucacc aagaugaagg agaucgccga ggccuaccuc      420

ggcuaccccg ucaccaacgc cgucaucacc guccccgccu acuucaacga cucccagcgc      480

caggccacca aggacgccgg cgucaucgcc ggccucaacg uccuccgcau caucaacgag      540

cccaccgccg ccgccaucgc cuacggccuc gaccgcaccg gcaagggcga gcgcaacguc      600

cucaucuucg accucggcgg cggcaccuuc gacgucucca uccucaccau cgacgacggc      660

aucuucgagg ucaaggccac cgccggcgac acccaccucg gcggcgagga cuucgacaac      720

cgccucguca accacuucgu cgaggaguuc aagcgcaagc acaagaagga caucucccag      780

aacaagcgcg ccguccgccg ccuccgcacc gccugcgagc gcgccaagcg cacccucucc      840

uccuccaccc aggccucccu cgagaucgac ucccucuucg agggcaucga cuucuacacc      900

uccaucaccc gcgcccgcuu cgaggagcuc ugcuccgacc ucuuccgcuc cacccucgag      960

cccgucgaga aggcccuccg cgacgccaag cucgacaagg cccagaucca cgaccucguc     1020

cucgucggcg gcuccacccg cauccccaag guccagaagc uccuccagga cuucuucaac     1080

ggccgcgacc ucaacaaguc caucaacccc gacgaggccg ucgccuacgg cgccgccguc     1140

caggccgcca uccucauggg cgacaagucc gagaacgucc aggaccuccu ccuccucgac     1200

gucgcccccc ucucccucgg ccucgagacc gccggcggcg ucaugaccgc ccucaucaag     1260

cgcaacucca ccauccccac caagcagacc cagaucuuca ccaccuacuc cgacaaccag     1320

cccggcgucc ucauccaggu cuacgagggc gagcgcgcca ugaccaagga caacaaccuc     1380

cucggccgcu ucgagcucuc cggcaucccc cccgcccccc gcggcguccc ccagaucgag     1440

gucaccuucg acaucgacgc caacggcauc cucaacguca ccgccaccga caaguccacc     1500

ggcaaggcca acaagaucac caucaccaac gacaagggcc gccucuccaa ggaggagauc     1560

gagcgcaugg uccaggaggc cgagaaguac aaggccgagg acgaggucca gcgcgagcgc     1620

gucuccgcca agaacgcccu cgaguccuac gccuucaaca ugaaguccgc cgucgaggac     1680

gagggccuca agggcaagau cuccgaggcc gacaagaaga agguccucga caagugccag     1740

gaggucaucu ccuggcucga cgccaacacc cucgccgaga aggacgaguu cgagcacaag     1800

cgcaaggagc ucgagcaggu cugcaacccc aucaucuccg gccucuacca gggcgccggc     1860

ggccccggcc ccggcggcuu cggcgcccag ggccccaagg gcggcuccgg cuccggcccc     1920

accaucgagg aggucgacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1619
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt2)

<400>  1619
gggagaaagc uuaccauggc caaggccgcc gccaucggca ucgaccucgg caccaccuac       60

uccugcgucg gcgucuucca gcacggcaag gucgagauca ucgccaacga ccagggcaac      120

cgcaccaccc ccuccuacgu cgccuucacc gacaccgagc gccucaucgg cgacgccgcc      180

aagaaccagg ucgcccucaa cccccagaac accgucuucg acgccaagcg ccucaucggc      240

cgcaaguucg gcgaccccgu cguccagucc gacaugaagc acuggcccuu ccaggucauc      300

aacgacggcg acaagcccaa gguccagguc uccuacaagg gcgagaccaa ggccuucuac      360

cccgaggaga ucuccuccau gguccucacc aagaugaagg agaucgccga ggccuaccuc      420

ggcuaccccg ucaccaacgc cgucaucacc guccccgccu acuucaacga cucccagcgc      480

caggccacca aggacgccgg cgucaucgcc ggccucaacg uccuccgcau caucaacgag      540

cccaccgccg ccgccaucgc cuacggccuc gaccgcaccg gcaagggcga gcgcaacguc      600

cucaucuucg accucggcgg cggcaccuuc gacgucucca uccucaccau cgacgacggc      660

aucuucgagg ucaaggccac cgccggcgac acccaccucg gcggcgagga cuucgacaac      720

cgccucguca accacuucgu cgaggaguuc aagcgcaagc acaagaagga caucucccag      780

aacaagcgcg ccguccgccg ccuccgcacc gccugcgagc gcgccaagcg cacccucucc      840

uccuccaccc aggccucccu cgagaucgac ucccucuucg agggcaucga cuucuacacc      900

uccaucaccc gcgcccgcuu cgaggagcuc ugcuccgacc ucuuccgcuc cacccucgag      960

cccgucgaga aggcccuccg cgacgccaag cucgacaagg cccagaucca cgaccucguc     1020

cucgucggcg gcuccacccg cauccccaag guccagaagc uccuccagga cuucuucaac     1080

ggccgcgacc ucaacaaguc caucaacccc gacgaggccg ucgccuacgg cgccgccguc     1140

caggccgcca uccucauggg cgacaagucc gagaacgucc aggaccuccu ccuccucgac     1200

gucgcccccc ucucccucgg ccucgagacc gccggcggcg ucaugaccgc ccucaucaag     1260

cgcaacucca ccauccccac caagcagacc cagaucuuca ccaccuacuc cgacaaccag     1320

cccggcgucc ucauccaggu cuacgagggc gagcgcgcca ugaccaagga caacaaccuc     1380

cucggccgcu ucgagcucuc cggcaucccc cccgcccccc gcggcguccc ccagaucgag     1440

gucaccuucg acaucgacgc caacggcauc cucaacguca ccgccaccga caaguccacc     1500

ggcaaggcca acaagaucac caucaccaac gacaagggcc gccucuccaa ggaggagauc     1560

gagcgcaugg uccaggaggc cgagaaguac aaggccgagg acgaggucca gcgcgagcgc     1620

gucuccgcca agaacgcccu cgaguccuac gccuucaaca ugaaguccgc cgucgaggac     1680

gagggccuca agggcaagau cuccgaggcc gacaagaaga agguccucga caagugccag     1740

gaggucaucu ccuggcucga cgccaacacc cucgccgaga aggacgaguu cgagcacaag     1800

cgcaaggagc ucgagcaggu cugcaacccc aucaucuccg gccucuacca gggcgccggc     1860

ggccccggcc ccggcggcuu cggcgcccag ggccccaagg gcggcuccgg cuccggcccc     1920

accaucgagg aggucgacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1620
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt2)

<400>  1620
gggagaaagc uuaccauggc caccgccaag ggcaucgcca ucggcaucga ccucggcacc       60

accuacuccu gcgucggcgu cuuccagcac ggcaaggucg agaucaucgc caacgaccag      120

ggcaaccgca ccacccccuc cuacgucgcc uucaccgaca ccgagcgccu caucggcgac      180

gccgccaaga accaggucgc caugaacccc cagaacaccg ucuucgacgc caagcgccuc      240

aucggccgca aguucaacga ccccgucguc caggccgaca ugaagcucug gcccuuccag      300

gucaucaacg agggcggcaa gcccaagguc cucgucuccu acaagggcga gaacaaggcc      360

uucuaccccg aggagaucuc cuccaugguc cucaccaagc ucaaggagac cgccgaggcc      420

uuccucggcc accccgucac caacgccguc aucaccgucc ccgccuacuu caacgacucc      480

cagcgccagg ccaccaagga cgccggcguc aucgccggcc ucaacguccu ccgcaucauc      540

aacgagccca ccgccgccgc caucgccuac ggccucgaca agggcggcca gggcgagcgc      600

cacguccuca ucuucgaccu cggcggcggc accuucgacg ucuccauccu caccaucgac      660

gacggcaucu ucgaggucaa ggccaccgcc ggcgacaccc accucggcgg cgaggacuuc      720

gacaaccgcc ucgucuccca cuucgucgag gaguucaagc gcaagcacaa gaaggacauc      780

ucccagaaca agcgcgccgu ccgccgccuc cgcaccgccu gcgagcgcgc caagcgcacc      840

cucuccuccu ccacccaggc caaccucgag aucgacuccc ucuacgaggg caucgacuuc      900

uacaccucca ucacccgcgc ccgcuucgag gagcucugcg ccgaccucuu ccgcggcacc      960

cucgagcccg ucgagaaggc ccuccgcgac gccaagaugg acaaggccaa gauccacgac     1020

aucguccucg ucggcggcuc cacccgcauc cccaaggucc agcgccuccu ccaggacuac     1080

uucaacggcc gcgaccucaa caaguccauc aaccccgacg aggccgucgc cuacggcgcc     1140

gccguccagg ccgccauccu caugggcgac aaguccgaga agguccagga ccuccuccuc     1200

cucgacgucg ccccccucuc ccucggccuc gagaccgccg gcggcgucau gaccgcccuc     1260

aucaagcgca acuccaccau ccccaccaag cagacccaga ucuucaccac cuacuccgac     1320

aaccagcccg gcguccucau ccaggucuac gagggcgagc gcgccaugac caaggacaac     1380

aaccuccucg gccgcuucga ccucaccggc aucccccccg ccccccgcgg cgucccccag     1440

aucgagguca ccuucgacau cgacgccaac ggcauccuca acgucaccgc caccgacaag     1500

uccaccggca aggucaacaa gaucaccauc accaacgaca agggccgccu cuccaaggag     1560

gagaucgagc gcaugguccu cgacgccgag aaguacaagg ccgaggacga gguccagcgc     1620

gagaagaucg ccgccaagaa cgcccucgag uccuacgccu ucaacaugaa guccgucguc     1680

uccgacgagg gccucaaggg caagaucucc gaguccgaca agaacaagau ccucgacaag     1740

ugcaacgagc uccucuccug gcucgagguc aaccagcucg ccgagaagga cgaguucgac     1800

cacaagcgca aggagcucga gcagaugugc aaccccauca ucaccaagcu cuaccagggc     1860

ggcugcaccg gccccgccug cggcaccggc uacguccccg gccgccccgc caccggcccc     1920

accaucgagg aggucgacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1621
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt2)

<400>  1621
gggagaaagc uuaccauguc cgcccgcggc cccgccaucg gcaucgaccu cggcaccacc       60

uacuccugcg ucggcgucuu ccagcacggc aaggucgaga ucaucgccaa cgaccagggc      120

aaccgcacca cccccuccua cgucgccuuc accgacaccg agcgccucau cggcgacgcc      180

gccaagaacc aggucgccau gaaccccacc aacaccaucu ucgacgccaa gcgccucauc      240

ggccgcaagu ucgaggacgc caccguccag uccgacauga agcacuggcc cuuccgcguc      300

gucuccgagg gcggcaagcc caagguccag gucgaguaca agggcgagac caagaccuuc      360

uuccccgagg agaucuccuc caugguccuc accaagauga aggagaucgc cgaggccuac      420

cucggcggca agguccacuc cgccgucauc accguccccg ccuacuucaa cgacucccag      480

cgccaggcca ccaaggacgc cggcaccauc accggccuca acguccuccg caucaucaac      540

gagcccaccg ccgccgccau cgccuacggc cucgacaaga agggcugcgc cggcggcgag      600

aagaacgucc ucaucuucga ccucggcggc ggcaccuucg acgucuccau ccucaccauc      660

gaggacggca ucuucgaggu caaguccacc gccggcgaca cccaccucgg cggcgaggac      720

uucgacaacc gcauggucuc ccaccucgcc gaggaguuca agcgcaagca caagaaggac      780

aucggcccca acaagcgcgc cguccgccgc cuccgcaccg ccugcgagcg cgccaagcgc      840

acccucuccu ccuccaccca ggccuccauc gagaucgacu cccucuacga gggcgucgac      900

uucuacaccu ccaucacccg cgcccgcuuc gaggagcuca acgccgaccu cuuccgcggc      960

acccucgagc ccgucgagaa ggcccuccgc gacgccaagc ucgacaaggg ccagauccag     1020

gagaucgucc ucgucggcgg cuccacccgc auccccaaga uccagaagcu ccuccaggac     1080

uucuucaacg gcaaggagcu caacaagucc aucaaccccg acgaggccgu cgccuacggc     1140

gccgccgucc aggccgccau ccucaucggc gacaaguccg agaacgucca ggaccuccuc     1200

cuccucgacg ucaccccccu cucccucggc aucgagaccg ccggcggcgu caugaccccc     1260

cucaucaagc gcaacaccac cauccccacc aagcagaccc agaccuucac caccuacucc     1320

gacaaccagu ccuccguccu cguccagguc uacgagggcg agcgcgccau gaccaaggac     1380

aacaaccucc ucggcaaguu cgaccucacc ggcauccccc ccgccccccg cggcgucccc     1440

cagaucgagg ucaccuucga caucgacgcc aacggcaucc ucaacgucac cgccgccgac     1500

aaguccaccg gcaaggagaa caagaucacc aucaccaacg acaagggccg ccucuccaag     1560

gacgacaucg accgcauggu ccaggaggcc gagcgcuaca aguccgagga cgaggccaac     1620

cgcgaccgcg ucgccgccaa gaacgcccuc gaguccuaca ccuacaacau caagcagacc     1680

gucgaggacg agaagcuccg cggcaagauc uccgagcagg acaagaacaa gauccucgac     1740

aagugccagg aggucaucaa cuggcucgac cgcaaccaga uggccgagaa ggacgaguac     1800

gagcacaagc agaaggagcu cgagcgcguc ugcaacccca ucaucuccaa gcucuaccag     1860

ggcggccccg gcggcggcuc cggcggcggc ggcuccggcg ccuccggcgg ccccaccauc     1920

gaggaggucg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  1622
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt2)

<400>  1622
gggagaaagc uuaccauguc cgucgucggc aucgaccucg gcuuccaguc cugcuacguc       60

gccgucgccc gcgccggcgg caucgagacc aucgccaacg aguacuccga ccgcugcacc      120

cccgccugca ucuccuucgg ccccaagaac cgcuccaucg gcgccgccgc caagucccag      180

gucaucucca acgccaagaa caccguccag ggcuucaagc gcuuccacgg ccgcgccuuc      240

uccgaccccu ucgucgaggc cgagaagucc aaccucgccu acgacaucgu ccagcucccc      300

accggccuca ccggcaucaa ggucaccuac auggaggagg agcgcaacuu caccaccgag      360

caggucaccg ccaugcuccu cuccaagcuc aaggagaccg ccgaguccgu ccucaagaag      420

cccgucgucg acugcgucgu cuccgucccc ugcuucuaca ccgacgccga gcgccgcucc      480

gucauggacg ccacccagau cgccggccuc aacugccucc gccucaugaa cgagaccacc      540

gccgucgccc ucgccuacgg caucuacaag caggaccucc ccgcccucga ggagaagccc      600

cgcaacgucg ucuucgucga caugggccac uccgccuacc aggucuccgu cugcgccuuc      660

aaccgcggca agcucaaggu ccucgccacc gccuucgaca ccacccucgg cggccgcaag      720

uucgacgagg uccucgucaa ccacuucugc gaggaguucg gcaagaagua caagcucgac      780

aucaagucca agauccgcgc ccuccuccgc cucucccagg agugcgagaa gcucaagaag      840

cucauguccg ccaacgccuc cgaccucccc cucuccaucg agugcuucau gaacgacguc      900

gacgucuccg gcaccaugaa ccgcggcaag uuccucgaga ugugcaacga ccuccucgcc      960

cgcgucgagc ccccccuccg cuccguccuc gagcagacca agcucaagaa ggaggacauc     1020

uacgccgucg agaucgucgg cggcgccacc cgcauccccg ccgucaagga gaagaucucc     1080

aaguucuucg gcaaggagcu cuccaccacc cucaacgccg acgaggccgu cacccgcggc     1140

ugcgcccucc agugcgccau ccucuccccc gccuucaagg uccgcgaguu cuccaucacc     1200

gacgucgucc ccuaccccau cucccuccgc uggaacuccc ccgccgagga gggcuccucc     1260

gacugcgagg ucuucuccaa gaaccacgcc gcccccuucu ccaagguccu caccuucuac     1320

cgcaaggagc ccuucacccu cgaggccuac uacuccuccc cccaggaccu ccccuacccc     1380

gaccccgcca ucgcccaguu cuccguccag aaggucaccc cccaguccga cggcuccucc     1440

uccaagguca aggucaaggu ccgcgucaac guccacggca ucuucuccgu cuccuccgcc     1500

ucccucgucg agguccacaa guccgaggag aacgaggagc ccauggagac cgaccagaac     1560

gccaaggagg aggagaagau gcaggucgac caggaggagc cccacgucga ggagcagcag     1620

cagcagaccc ccgccgagaa caaggccgag uccgaggaga uggagaccuc ccaggccggc     1680

uccaaggaca agaagaugga ccagcccccc caggccaaga aggccaaggu caagaccucc     1740

accgucgacc uccccaucga gaaccagcuc cucuggcaga ucgaccgcga gaugcucaac     1800

cucuacaucg agaacgaggg caagaugauc augcaggaca agcucgagaa ggagcgcaac     1860

gacgccaaga acgccgucga ggaguacguc uacgagaugc gcgacaagcu cuccggcgag     1920

uacgagaagu ucgucuccga ggacgaccgc aacuccuuca cccucaagcu cgaggacacc     1980

gagaacuggc ucuacgagga cggcgaggac cagcccaagc aggucuacgu cgacaagcuc     2040

gccgagcuca agaaccucgg ccagcccauc aagauccgcu uccaggaguc cgaggagcgc     2100

cccaagcucu ucgaggagcu cggcaagcag auccagcagu acaugaagau caucuccucc     2160

uucaagaaca aggaggacca guacgaccac cucgacgccg ccgacaugac caaggucgag     2220

aaguccacca acgaggccau ggaguggaug aacaacaagc ucaaccucca gaacaagcag     2280

ucccucacca uggaccccgu cgucaagucc aaggagaucg aggccaagau caaggagcuc     2340

accuccaccu gcucccccau caucuccaag cccaagccca aggucgagcc ccccaaggag     2400

gagcagaaga acgccgagca gaacggcccc gucgacggcc agggcgacaa ccccggcccc     2460

caggccgccg agcagggcac cgacaccgcc guccccuccg acuccgacaa gaagcucccc     2520

gagauggaca ucgacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  1623
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt2)

<400>  1623
gggagaaagc uuaccauguc cgucgucggc aucgaccucg gcuuccucaa cugcuacauc       60

gccgucgccc gcuccggcgg caucgagacc aucgccaacg aguacuccga ccgcugcacc      120

cccgccugca ucucccucgg cucccgcacc cgcgccaucg gcaacgccgc caagucccag      180

aucgucacca acguccgcaa caccauccac ggcuucaaga agcuccacgg ccgcuccuuc      240

gacgacccca ucguccagac cgagcgcauc cgccuccccu acgagcucca gaagaugccc      300

aacggcuccg ccggcgucaa gguccgcuac cucgaggagg agcgccccuu cgccaucgag      360

caggucaccg gcaugcuccu cgccaagcuc aaggagaccu ccgagaacgc ccucaagaag      420

cccgucgccg acugcgucau cuccaucccc uccuucuuca ccgacgccga gcgccgcucc      480

gucauggccg ccgcccaggu cgccggccuc aacugccucc gccucaugaa cgagaccacc      540

gccgucgccc ucgccuacgg caucuacaag caggaccucc ccccccucga cgagaagccc      600

cgcaacgucg ucuucaucga caugggccac uccgccuacc agguccucgu cugcgccuuc      660

aacaagggca agcucaaggu ccucgccacc accuucgacc ccuaccucgg cggccgcaac      720

uucgacgagg cccucgucga cuacuucugc gacgaguuca agaccaagua caagaucaac      780

gucaaggaga acucccgcgc ccuccuccgc cucuaccagg agugcgagaa gcucaagaag      840

cucauguccg ccaacgccuc cgaccucccc cucaacaucg agugcuucau gaacgaccuc      900

gacgucuccu ccaagaugaa ccgcgcccag uucgagcagc ucugcgccuc ccuccucgcc      960

cgcgucgagc ccccccucaa ggccgucaug gagcaggcca accuccagcg cgaggacauc     1020

uccuccaucg agaucgucgg cggcgccacc cgcauccccg ccgucaagga gcagaucacc     1080

aaguucuucc ucaaggacau cuccaccacc cucaacgccg acgaggccgu cgcccgcggc     1140

ugcgcccucc agugcgccau ccucuccccc gccuucaagg uccgcgaguu cuccaucacc     1200

gaccucgucc ccuacuccau cacccuccgc uggaagaccu ccuucgagga cggcuccggc     1260

gagugcgagg ucuucugcaa gaaccacccc gcccccuucu ccaaggucau caccuuccac     1320

aagaaggagc ccuucgagcu cgaggccuuc uacaccaacc uccacgaggu ccccuacccc     1380

gacgcccgca ucggcuccuu caccauccag aacgucuucc cccaguccga cggcgacucc     1440

uccaagguca aggucaaggu ccgcgucaac auccacggca ucuucuccgu cgccuccgcc     1500

uccgucaucg agaagcagaa ccucgagggc gaccacuccg acgcccccau ggagaccgag     1560

accuccuuca agaacgagaa caaggacaac auggacaaga ugcaggucga ccaggaggag     1620

ggccaccaga agugccacgc cgagcacacc cccgaggagg agaucgacca caccggcgcc     1680

aagaccaagu ccgccgucuc cgacaagcag gaccgccuca accagacccu caagaagggc     1740

aaggucaagu ccaucgaccu ccccauccag uccucccucu gccgccagcu cggccaggac     1800

cuccucaacu ccuacaucga gaacgagggc aagaugauca ugcaggacaa gcucgagaag     1860

gagcgcaacg acgccaagaa cgccgucgag gaguacgucu acgacuuccg cgaccgccuc     1920

ggcaccgucu acgagaaguu caucaccccc gaggaccucu ccaagcucuc cgccguccuc     1980

gaggacaccg agaacuggcu cuacgaggac ggcgaggacc agcccaagca ggucuacguc     2040

gacaagcucc aggagcucaa gaaguacggc cagcccaucc agaugaagua cauggagcac     2100

gaggagcgcc ccaaggcccu caacgaccuc ggcaagaaga uccagcucgu caugaagguc     2160

aucgaggccu accgcaacaa ggacgagcgc uacgaccacc ucgaccccac cgagauggag     2220

aaggucgaga agugcaucuc cgacgccaug uccuggcuca acuccaagau gaacgcccag     2280

aacaagcucu cccucaccca ggaccccguc gucaaggucu ccgagaucgu cgccaagucc     2340

aaggagcucg acaacuucug caaccccauc aucuacaagc ccaagcccaa ggccgagguc     2400

cccgaggaca agcccaaggc caacuccgag cacaacggcc ccauggacgg ccaguccggc     2460

accgagacca aguccgacuc caccaaggac uccucccagc acaccaaguc cuccggcgag     2520

auggaggucg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  1624
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt2)

<400>  1624
gggagaaagc uuaccaugaa gcucucccuc gucgccgcca ugcuccuccu ccucuccgcc       60

gcccgcgccg aggaggagga caagaaggag gacgucggca ccgucgucgg caucgaccuc      120

ggcaccaccu acuccugcgu cggcgucuuc aagaacggcc gcgucgagau caucgccaac      180

gaccagggca accgcaucac ccccuccuac gucgccuuca cccccgaggg cgagcgccuc      240

aucggcgacg ccgccaagaa ccagcucacc uccaaccccg agaacaccgu cuucgacgcc      300

aagcgccuca ucggccgcac cuggaacgac cccuccgucc agcaggacau caaguuccuc      360

cccuucaagg ucgucgagaa gaagaccaag cccuacaucc aggucgacau cggcggcggc      420

cagaccaaga ccuucgcccc cgaggagauc uccgccaugg uccucaccaa gaugaaggag      480

accgccgagg ccuaccucgg caagaagguc acccacgccg ucgucaccgu ccccgccuac      540

uucaacgacg cccagcgcca ggccaccaag gacgccggca ccaucgccgg ccucaacguc      600

augcgcauca ucaacgagcc caccgccgcc gccaucgccu acggccucga caagcgcgag      660

ggcgagaaga acauccucgu cuucgaccuc ggcggcggca ccuucgacgu cucccuccuc      720

accaucgaca acggcgucuu cgaggucguc gccaccaacg gcgacaccca ccucggcggc      780

gaggacuucg accagcgcgu cauggagcac uucaucaagc ucuacaagaa gaagaccggc      840

aaggacgucc gcaaggacaa ccgcgccguc cagaagcucc gccgcgaggu cgagaaggcc      900

aagcgcgccc ucuccuccca gcaccaggcc cgcaucgaga ucgaguccuu cuacgagggc      960

gaggacuucu ccgagacccu cacccgcgcc aaguucgagg agcucaacau ggaccucuuc     1020

cgcuccacca ugaagcccgu ccagaagguc cucgaggacu ccgaccucaa gaaguccgac     1080

aucgacgaga ucguccucgu cggcggcucc acccgcaucc ccaagaucca gcagcucguc     1140

aaggaguucu ucaacggcaa ggagcccucc cgcggcauca accccgacga ggccgucgcc     1200

uacggcgccg ccguccaggc cggcguccuc uccggcgacc aggacaccgg cgaccucguc     1260

cuccucgacg ucugcccccu cacccucggc aucgagaccg ucggcggcgu caugaccaag     1320

cucauccccc gcaacaccgu cguccccacc aagaaguccc agaucuucuc caccgccucc     1380

gacaaccagc ccaccgucac caucaagguc uacgagggcg agcgcccccu caccaaggac     1440

aaccaccucc ucggcaccuu cgaccucacc ggcauccccc ccgccccccg cggcgucccc     1500

cagaucgagg ucaccuucga gaucgacguc aacggcaucc uccgcgucac cgccgaggac     1560

aagggcaccg gcaacaagaa caagaucacc aucaccaacg accagaaccg ccucaccccc     1620

gaggagaucg agcgcauggu caacgacgcc gagaaguucg ccgaggagga caagaagcuc     1680

aaggagcgca ucgacacccg caacgagcuc gaguccuacg ccuacucccu caagaaccag     1740

aucggcgaca aggagaagcu cggcggcaag cucuccuccg aggacaagga gaccauggag     1800

aaggccgucg aggagaagau cgaguggcuc gagucccacc aggacgccga caucgaggac     1860

uucaaggcca agaagaagga gcucgaggag aucguccagc ccaucaucuc caagcucuac     1920

ggcuccgccg gccccccccc caccggcgag gaggacaccg ccgagaagga cgagcucuga     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  1625
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt2)

<400>  1625
gggagaaagc uuaccaugca ggccccccgc gagcucgccg ucggcaucga ccucggcacc       60

accuacuccu gcgucggcgu cuuccagcag ggccgcgucg agauccucgc caacgaccag      120

ggcaaccgca ccacccccuc cuacgucgcc uucaccgaca ccgagcgccu cgucggcgac      180

gccgccaagu cccaggccgc ccucaacccc cacaacaccg ucuucgacgc caagcgccuc      240

aucggccgca aguucgccga caccaccguc caguccgaca ugaagcacug gcccuuccgc      300

gucgucuccg agggcggcaa gcccaagguc cgcgucugcu accgcggcga ggacaagacc      360

uucuaccccg aggagaucuc cuccaugguc cucuccaaga ugaaggagac cgccgaggcc      420

uaccucggcc agcccgucaa gcacgccguc aucaccgucc ccgccuacuu caacgacucc      480

cagcgccagg ccaccaagga cgccggcgcc aucgccggcc ucaacguccu ccgcaucauc      540

aacgagccca ccgccgccgc caucgccuac ggccucgacc gccgcggcgc cggcgagcgc      600

aacguccuca ucuucgaccu cggcggcggc accuucgacg ucuccguccu cuccaucgac      660

gccggcgucu ucgaggucaa ggccaccgcc ggcgacaccc accucggcgg cgaggacuuc      720

gacaaccgcc ucgucaacca cuucauggag gaguuccgcc gcaagcacgg caaggaccuc      780

uccggcaaca agcgcgcccu ccgccgccuc cgcaccgccu gcgagcgcgc caagcgcacc      840

cucuccuccu ccacccaggc cacccucgag aucgacuccc ucuucgaggg cgucgacuuc      900

uacaccucca ucacccgcgc ccgcuucgag gagcucugcu ccgaccucuu ccgcuccacc      960

cucgagcccg ucgagaaggc ccuccgcgac gccaagcucg acaaggccca gauccacgac     1020

gucguccucg ucggcggcuc cacccgcauc cccaaggucc agaagcuccu ccaggacuuc     1080

uucaacggca aggagcucaa caaguccauc aaccccgacg aggccgucgc cuacggcgcc     1140

gccguccagg ccgccguccu caugggcgac aagugcgaga agguccagga ccuccuccuc     1200

cucgacgucg ccccccucuc ccucggccuc gagaccgccg gcggcgucau gaccacccuc     1260

auccagcgca acgccaccau ccccaccaag cagacccaga ccuucaccac cuacuccgac     1320

aaccagcccg gcgucuucau ccaggucuac gagggcgagc gcgccaugac caaggacaac     1380

aaccuccucg gccgcuucga gcucuccggc aucccccccg ccccccgcgg cgucccccag     1440

aucgagguca ccuucgacau cgacgccaac ggcauccucu ccgucaccgc caccgaccgc     1500

uccaccggca aggccaacaa gaucaccauc accaacgaca agggccgccu cuccaaggag     1560

gaggucgagc gcauggucca cgaggccgag caguacaagg ccgaggacga ggcccagcgc     1620

gaccgcgucg ccgccaagaa cucccucgag gcccacgucu uccacgucaa gggcucccuc     1680

caggaggagu cccuccgcga caagaucccc gaggaggacc gccgcaagau gcaggacaag     1740

ugccgcgagg uccucgccug gcucgagcac aaccagcucg ccgagaagga ggaguacgag     1800

caccagaagc gcgagcucga gcagaucugc cgccccaucu ucucccgccu cuacggcggc     1860

cccggcgucc ccggcggcuc cuccugcggc acccaggccc gccagggcga ccccuccacc     1920

ggccccauca ucgaggaggu cgacugagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  1626
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt2)

<400>  1626
gggagaaagc uuaccaugca ggccccccgc gagcucgccg ucggcaucga ccucggcacc       60

accuacuccu gcgucggcgu cuuccagcag ggccgcgucg agauccucgc caacgaccag      120

ggcaaccgca ccacccccuc cuacgucgcc uucaccgaca ccgagcgccu cgucggcgac      180

gccgccaagu cccaggccgc ccucaacccc cacaacaccg ucuucgacgc caagcgccuc      240

aucggccgca aguucgccga caccaccguc caguccgaca ugaagcacug gcccuuccag      300

gucgucuccg agggcggcaa gcccaagguc cgcgucugcu accgcggcga ggacaagacc      360

uucuaccccg aggagaucuc cuccaugguc cucuccaaga ugaaggagac cgccgaggcc      420

uaccucggcc agcccgucaa gcacgccguc aucaccgucc ccaccuacuu cuccaacucc      480

cagcgccagg ccaccaagga cgccggcgcc aucgccggcc ucaagguccu ccccaucauc      540

aacgaggcca ccgccgccgc caucgccuac ggccucgacc gccgcggcgc cggcaagcgc      600

aacguccuca ucuucgaccu cggcggcggc accuucgacg ucuccguccu cuccaucgac      660

gccggcgucu ucgaggucaa ggccaccgcc ggcgacaccc accucggcgg cgaggacuuc      720

gacaaccgcc ucgucaacca cuucauggag gaguuccgcc gcaagcacgg caaggaccuc      780

uccggcaaca agcgcgcccu ccgccgccuc cgcaccgccu gcgagcgcgc caagcgcacc      840

cccuccuccu ccacccaggc cacccucgag aucgacuccc ucuucgaggg cgucgacuuc      900

uacaagucca ucacccgcgc ccgcuucgag gagcucugcu ccgaccucuu ccgcuccacc      960

cucgagcccg ucgagaaggc ccuccgcgac gccaagcucg acaaggccca gauccacgac     1020

uucguccucg gcggcggccu ccacucccac ccccagggcg ccgaggucgc cgccggccuc     1080

cuccagcgcc agggcgccga gcaggagcac cagcccugag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  1627
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt2)

<400>  1627
gggagaaagc uuaccauguc caagggcccc gccgucggca ucgaccucgg caccaccuac       60

uccugcgucg gcgucuucca gcacggcaag gucgagauca ucgccaacga ccagggcaac      120

cgcaccaccc ccuccuacgu cgccuucacc gacaccgagc gccucaucgg cgacgccgcc      180

aagaaccagg ucgccaugaa ccccaccaac accgucuucg acgccaagcg ccucaucggc      240

cgccgcuucg acgacgccgu cguccagucc gacaugaagc acuggcccuu cauggucguc      300

aacgacgccg gccgccccaa gguccagguc gaguacaagg gcgagaccaa guccuucuac      360

cccgaggagg ucuccuccau gguccucacc aagaugaagg agaucgccga ggccuaccuc      420

ggcaagaccg ucaccaacgc cgucgucacc guccccgccu acuucaacga cucccagcgc      480

caggccacca aggacgccgg caccaucgcc ggccucaacg uccuccgcau caucaacgag      540

cccaccgccg ccgccaucgc cuacggccuc gacaagaagg ucggcgccga gcgcaacguc      600

cucaucuucg accucggcgg cggcaccuuc gacgucucca uccucaccau cgaggacggc      660

aucuucgagg ucaaguccac cgccggcgac acccaccucg gcggcgagga cuucgacaac      720

cgcaugguca accacuucau cgccgaguuc aagcgcaagc acaagaagga caucuccgag      780

aacaagcgcg ccguccgccg ccuccgcacc gccugcgagc gcgccaagcg cacccucucc      840

uccuccaccc aggccuccau cgagaucgac ucccucuacg agggcaucga cuucuacacc      900

uccaucaccc gcgcccgcuu cgaggagcuc aacgccgacc ucuuccgcgg cacccucgac      960

cccgucgaga aggcccuccg cgacgccaag cucgacaagu cccagaucca cgacaucguc     1020

cucgucggcg gcuccacccg cauccccaag auccagaagc uccuccagga cuucuucaac     1080

ggcaaggagc ucaacaaguc caucaacccc gacgaggccg ucgccuacgg cgccgccguc     1140

caggccgcca uccucuccgg cgacaagucc gagaacgucc aggaccuccu ccuccucgac     1200

gucacccccc ucucccucgg caucgagacc gccggcggcg ucaugaccgu ccucaucaag     1260

cgcaacacca ccauccccac caagcagacc cagaccuuca ccaccuacuc cgacaaccag     1320

cccggcgucc ucauccaggu cuacgagggc gagcgcgcca ugaccaagga caacaaccuc     1380

cucggcaagu ucgagcucac cggcaucccc cccgcccccc gcggcguccc ccagaucgag     1440

gucaccuucg acaucgacgc caacggcauc cucaacgucu ccgccgucga caaguccacc     1500

ggcaaggaga acaagaucac caucaccaac gacaagggcc gccucuccaa ggaggacauc     1560

gagcgcaugg uccaggaggc cgagaaguac aaggccgagg acgagaagca gcgcgacaag     1620

gucuccucca agaacucccu cgaguccuac gccuucaaca ugaaggccac cgucgaggac     1680

gagaagcucc agggcaagau caacgacgag gacaagcaga agauccucga caagugcaac     1740

gagaucauca acuggcucga caagaaccag accgccgaga aggaggaguu cgagcaccag     1800

cagaaggagc ucgagaaggu cugcaacccc aucaucacca agcucuacca guccgccggc     1860

ggcaugcccg gcggcaugcc cggcggcuuc cccggcggcg gcgccccccc cuccggcggc     1920

gccuccuccg gccccaccau cgaggagguc gacugaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  1628
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt2)

<400>  1628
gggagaaagc uuaccaugau cuccgccucc cgcgccgccg ccgcccgccu cgucggcgcc       60

gccgccuccc gcggccccac cgccgcccgc caccaggacu ccuggaacgg ccucucccac      120

gaggccuucc gccucgucuc ccgccgcgac uacgccuccg aggccaucaa gggcgccguc      180

gucggcaucg accucggcac caccaacucc ugcgucgccg ucauggaggg caagcaggcc      240

aagguccucg agaacgccga gggcgcccgc accacccccu ccgucgucgc cuucaccgcc      300

gacggcgagc gccucgucgg caugcccgcc aagcgccagg ccgucaccaa ccccaacaac      360

accuucuacg ccaccaagcg ccucaucggc cgccgcuacg acgaccccga gguccagaag      420

gacaucaaga acguccccuu caagaucguc cgcgccucca acggcgacgc cugggucgag      480

gcccacggca agcucuacuc ccccucccag aucggcgccu ucguccucau gaagaugaag      540

gagaccgccg agaacuaccu cggccacacc gccaagaacg ccgucaucac cguccccgcc      600

uacuucaacg acucccagcg ccaggccacc aaggacgccg gccagaucuc cggccucaac      660

guccuccgcg ucaucaacga gcccaccgcc gccgcccucg ccuacggccu cgacaagucc      720

gaggacaagg ucaucgccgu cuacgaccuc ggcggcggca ccuucgacau cuccauccuc      780

gagauccaga agggcgucuu cgaggucaag uccaccaacg gcgacaccuu ccucggcggc      840

gaggacuucg accaggcccu ccuccgccac aucgucaagg aguucaagcg cgagaccggc      900

gucgaccuca ccaaggacaa cauggcccuc cagcgcgucc gcgaggccgc cgagaaggcc      960

aagugcgagc ucuccuccuc cguccagacc gacaucaacc uccccuaccu caccauggac     1020

uccuccggcc ccaagcaccu caacaugaag cucacccgcg cccaguucga gggcaucguc     1080

accgaccuca uccgccgcac caucgccccc ugccagaagg ccaugcagga cgccgagguc     1140

uccaaguccg acaucggcga ggucauccuc gucggcggca ugacccgcau gcccaagguc     1200

cagcagaccg uccaggaccu cuucggccgc gcccccucca aggccgucaa ccccgacgag     1260

gccgucgcca ucggcgccgc cauccagggc ggcguccucg ccggcgacgu caccgacguc     1320

cuccuccucg acgucacccc ccucucccuc ggcaucgaga cccucggcgg cgucuucacc     1380

aagcucauca accgcaacac caccaucccc accaagaagu cccaggucuu cuccaccgcc     1440

gccgacggcc agacccaggu cgagaucaag gucugccagg gcgagcgcga gauggccggc     1500

gacaacaagc uccucggcca guucacccuc aucggcaucc cccccgcccc ccgcggcguc     1560

ccccagaucg aggucaccuu cgacaucgac gccaacggca ucguccacgu cuccgccaag     1620

gacaagggca ccggccgcga gcagcagauc gucauccagu ccuccggcgg ccucuccaag     1680

gacgacaucg agaacauggu caagaacgcc gagaaguacg ccgaggagga ccgccgcaag     1740

aaggagcgcg ucgaggccgu caacauggcc gagggcauca uccacgacac cgagaccaag     1800

auggaggagu ucaaggacca gcuccccgcc gacgagugca acaagcucaa ggaggagauc     1860

uccaagaugc gcgagcuccu cgcccgcaag gacuccgaga ccggcgagaa cauccgccag     1920

gccgccuccu cccuccagca ggccucccuc aagcucuucg agauggccua caagaagaug     1980

gccuccgagc gcgagggcuc cggcuccucc ggcaccggcg agcagaagga ggaccagaag     2040

gaggagaagc agugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  1629
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt2)

<400>  1629
gggagaaagc uuaccauggc cgacaaggag gccggcggcu ccgacggccc ccgcgagacc       60

gcccccaccu ccgccuacuc cucccccgcc cgcucccucg gcgacaccgg caucaccccc      120

cucucccccu cccacaucgu caacgacacc gacuccaacg ucuccgagca gcaguccuuc      180

cucgucgucg ucgccgucga cuucggcacc accuccuccg gcuacgccua cuccuucacc      240

aaggagcccg agugcaucca cgucaugcgc cgcugggagg gcggcgaccc cggcgucucc      300

aaccagaaga cccccaccac cauccuccuc acccccgagc gcaaguucca cuccuucggc      360

uacgccgccc gcgacuucua ccacgaccuc gaccccaacg aggccaagca guggcucuac      420

cucgagaagu ucaagaugaa gcuccacacc accggcgacc ucaccaugga caccgaccuc      480

accgccgcca acggcaagaa ggucaaggcc cucgagaucu ucgccuacgc ccuccaguac      540

uucaaggagc aggcccucaa ggagcucucc gaccaggccg gcuccgaguu cgagaacucc      600

gacguccgcu gggucaucac cguccccgcc aucuggaagc agcccgccaa gcaguucaug      660

cgccaggccg ccuaccaggc cggccucgcc ucccccgaga acuccgagca gcucaucauc      720

gcccucgagc ccgaggccgc cuccaucuac ugccgcaagc uccgccucca ccagaugauc      780

gagcucuccu ccaaggccgc cgucaacggc uacuccggcu ccgacaccgu cggcgccggc      840

uucacccagg ccaaggagca cauccgccgc aaccgccagu cccgcaccuu ccucgucgag      900

aacgucaucg gcgagaucug guccgagcuc gaggagggcg acaaguacgu cgucgucgac      960

uccggcggcg gcaccgucga ccucaccguc caccagaucc gccuccccga gggccaccuc     1020

aaggagcucu acaaggccac cggcggcccc uacggcuccc ucggcgucga cuacgaguuc     1080

gagaagcucc ucuacaagau cuucggcgag gacuucaucg agcaguucaa gaucaagcgc     1140

cccgccgccu gggucgaccu caugaucgcc uucgaguccc gcaagcgcgc cgccgccccc     1200

gaccgcacca acccccucaa caucacccuc cccuucuccu ucaucgacua cuacaagaag     1260

uuccgcggcc acuccgucga gcacgcccuc cgcaagucca acgucgacuu cgucaagugg     1320

uccucccagg gcaugcuccg cauguccccc gacgccauga acgcccucuu caagcccacc     1380

aucgacucca ucaucgagca ccuccgcgac cucuuccaga agcccgaggu cuccaccguc     1440

aaguuccucu uccucgucgg cggcuucgcc gaggcccccc uccuccagca ggccguccag     1500

gccgccuucg gcgaccagug ccgcaucauc aucccccagg acgucggccu caccauccuc     1560

aagggcgccg uccucuucgg ccucgacccc gccgucauca agguccgccg cuccccccuc     1620

accuacggcg ucggcguccu caaccgcuac gucgagggca agcacccccc cgagaagcuc     1680

cucgucaagg acggcacccg cuggugcacc gacgucuucg acaaguucau cuccgccgac     1740

caguccgucg cccucggcga gcucgucaag cgcuccuaca cccccgccaa gcccucccag     1800

cucgucaucg ucaucaacau cuacuccucc gagcacgaca acgucuccuu caucaccgac     1860

cccggcguca agaagugcgg cacccuccgc cucgaccuca ccggcaccuc cggcaccgcc     1920

guccccgccc gccgcgagau ccagacccuc augcaguucg gcgacaccga gaucaaggcc     1980

accgccaucg acaucgccac cuccaagucc gucaaggucg gcaucgacuu ccucaacuac     2040

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  1630
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt2)

<400>  1630
gggagaaagc uuaccaugcu cgccgucccc gagaugggcc uccagggccu cuacaucggc       60

uccucccccg agcgcucccc cguccccucc ccccccggcu ccccccgcac ccaggagucc      120

ugcggcaucg ccccccucac ccccucccag ucccccaagc ccgagguccg cgccccccag      180

caggccuccu ucuccgucgu cgucgccauc gacuucggca ccaccuccuc cggcuacgcc      240

uucuccuucg ccuccgaccc cgaggccauc cacaugaugc gcaaguggga gggcggcgac      300

cccggcgucg cccaccagaa gacccccacc ugccuccucc ucacccccga gggcgccuuc      360

cacuccuucg gcuacaccgc ccgcgacuac uaccacgacc ucgaccccga ggaggcccgc      420

gacuggcucu acuucgagaa guucaagaug aagauccacu ccgccaccga ccucacccuc      480

aagacccagc ucgaggccgu caacggcaag accaugcccg cccucgaggu cuucgcccac      540

gcccuccgcu ucuuccgcga gcacgcccuc caggagcucc gcgagcaguc ccccucccuc      600

cccgagaagg acaccguccg cuggguccuc accguccccg ccaucuggaa gcagcccgcc      660

aagcaguuca ugcgcgaggc cgccuaccuc gccggccucg ucucccgcga gaacgccgag      720

cagcuccuca ucgcccucga gcccgaggcc gccuccgucu acugccgcaa gcuccgccuc      780

caccagcucc ucgaccucuc cggccgcgcc cccggcggcg gccgccucgg cgagcgccgc      840

uccaucgacu ccuccuuccg ccaggcccgc gagcagcucc gccgcucccg ccacucccgc      900

accuuccucg ucgaguccgg cgucggcgag cucugggccg agaugcaggc cggcgaccgc      960

uacgucgucg ccgacugcgg cggcggcacc gucgaccuca ccguccacca gcucgagcag     1020

ccccacggca cccucaagga gcucuacaag gccuccggcg gccccuacgg cgccgucggc     1080

gucgaccucg ccuucgagca gcuccucugc cgcaucuucg gcgaggacuu caucgccacc     1140

uucaagcgcc agcgccccgc cgccuggguc gaccucacca ucgccuucga ggcccgcaag     1200

cgcaccgccg gcccccaccg cgccggcgcc cucaacaucu cccuccccuu cuccuucauc     1260

gacuucuacc gcaagcagcg cggccacaac gucgagaccg cccuccgccg cuccuccguc     1320

aacuucguca agugguccuc ccagggcaug cuccgcaugu ccugcgaggc caugaacgag     1380

cucuuccagc ccaccgucuc cggcaucauc cagcacaucg aggcccuccu cgcccgcccc     1440

gagguccagg gcgucaagcu ccucuuccuc gucggcggcu ucgccgaguc cgccguccuc     1500

cagcacgccg uccaggccgc ccucggcgcc cgcggccucc gcgucgucgu cccccacgac     1560

gucggccuca ccauccucaa gggcgccguc cucuucggcc aggcccccgg cgucguccgc     1620

guccgccgcu ccccccucac cuacggcguc ggcguccuca accgcuucgu ccccggccgc     1680

cacccccccg agaagcuccu cguccgcgac ggccgccgcu ggugcaccga cgucuucgag     1740

cgcuucgucg ccgccgagca guccgucgcc cucggcgagg agguccgccg cuccuacugc     1800

cccgcccgcc ccggccagcg ccgcguccuc aucaaccucu acugcugcgc cgccgaggac     1860

gcccgcuuca ucaccgaccc cggcguccgc aagugcggcg cccucucccu cgagcucgag     1920

cccgccgacu gcggccagga caccgccggc gccccccccg gccgccgcga gauccgcgcc     1980

gccaugcagu ucggcgacac cgagaucaag gucaccgccg ucgacgucuc caccaaccgc     2040

uccguccgcg ccuccaucga cuuccucucc aacugaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  1631
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt2)

<400>  1631
gggagaaagc uuaccauggc ccgcgagaug accauccucg gcuccgccgu ccucacccuc       60

cuccucgccg gcuaccucgc ccagcaguac cucccccucc ccacccccaa ggucaucggc      120

aucgaccucg gcaccaccua cugcuccguc ggcgucuucu uccccggcac cggcaagguc      180

aaggucaucc ccgacgagaa cggccacauc uccauccccu ccauggucuc cuucaccgac      240

aacgacgucu acgucggcua cgaguccguc gagcucgccg acuccaaccc ccagaacacc      300

aucuacgacg ccaagcgcuu caucggcaag aucuucaccg ccgaggagcu cgaggccgag      360

aucggccgcu accccuucaa gguccucaac aagaacggca uggucgaguu cuccgucacc      420

uccaacgaga ccaucaccgu cucccccgag uacgucggcu cccgccuccu ccucaagcuc      480

aaggagaugg ccgaggccua ccucggcaug cccgucgcca acgccgucau cuccgucccc      540

gccgaguucg accucaagca gcgcaacucc accaucgagg ccgccaaccu cgccggccuc      600

aagauccucc gcgucaucaa cgagcccacc gccgccgcca uggccuacgg ccuccacaag      660

gccgacgucu uccacguccu cgucaucgac cucggcggcg gcacccucga cgucucccuc      720

cucaacaagc agggcggcau guuccucacc cgcgccaugu ccggcaacaa caagcucggc      780

ggccaggacu ucaaccagcg ccuccuccag uaccucuaca agcagaucua ccagaccuac      840

ggcuucgucc ccucccgcaa ggaggagauc caccgccucc gccaggccgu cgagaugguc      900

aagcucaacc ucacccucca ccaguccgcc cagcucuccg uccuccucac cgucgaggag      960

caggaccgca aggagcccca cuccuccgac accgagcucc ccaaggacaa gcucuccucc     1020

gccgacgacc accgcgucaa cuccggcuuc ggccgcggcc ucuccgacaa gaaguccggc     1080

gagucccagg uccucuucga gaccgagauc ucccgcaagc ucuucgacac ccucaacgag     1140

gaccucuucc agaagauccu cguccccauc cagcaggucc ucaaggaggg ccaccucgag     1200

aagaccgaga ucgacgaggu cguccucguc ggcggcucca cccgcauccc ccgcauccgc     1260

caggucaucc aggaguucuu cggcaaggac cccaacaccu ccgucgaccc cgaccucgcc     1320

gucgucaccg gcgucgccau ccaggccggc aucgacggcg gcuccuggcc ccuccagguc     1380

uccgcccucg agauccccaa caagcaccuc cagaagacca acuucaacug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  1632
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt2)

<400>  1632
gggagaaagc uuaccauggc cgccaucggc guccaccucg gcugcaccuc cgccugcguc       60

gccgucuaca aggacggccg cgccggcguc gucgccaacg acgccggcga ccgcgucacc      120

cccgccgucg ucgccuacuc cgagaacgag gagaucgucg gccucgccgc caagcagucc      180

cgcauccgca acaucuccaa caccgucaug aaggucaagc agauccucgg ccgcuccucc      240

uccgaccccc aggcccagaa guacaucgcc gaguccaagu gccucgucau cgagaagaac      300

ggcaagcucc gcuacgagau cgacaccggc gaggagacca aguucgucaa ccccgaggac      360

gucgcccgcc ucaucuucuc caagaugaag gagaccgccc acuccguccu cggcuccgac      420

gccaacgacg ucgucaucac cguccccuuc gacuucggcg agaagcagaa gaacgcccuc      480

ggcgaggccg cccgcgccgc cggcuucaac guccuccgcc ucauccacga gcccuccgcc      540

gcccuccucg ccuacggcau cggccaggac ucccccaccg gcaaguccaa cauccucguc      600

uucaagcucg gcggcaccuc ccucucccuc uccgucaugg aggucaacuc cggcaucuac      660

cgcguccucu ccaccaacac cgacgacaac aucggcggcg cccacuucac cgagacccuc      720

gcccaguacc ucgccuccga guuccagcgc uccuucaagc acgacguccg cggcaacgcc      780

cgcgccauga ugaagcucac caacuccgcc gaggucgcca agcacucccu cuccacccuc      840

ggcuccgcca acugcuuccu cgacucccuc uacgagggcc aggacuucga cugcaacguc      900

ucccgcgccc gcuucgagcu ccucugcucc ccccucuuca acaagugcau cgaggccauc      960

cgcggccucc ucgaccagaa cggcuucacc gccgacgaca ucaacaaggu cguccucugc     1020

ggcggcuccu cccgcauccc caagcuccag cagcucauca aggaccucuu ccccgccguc     1080

gagcuccuca acuccauccc ccccgacgag gucaucccca ucggcgccgc caucgaggcc     1140

ggcauccuca ucggcaagga gaaccuccuc gucgaggacu cccucaugau cgagugcucc     1200

gcccgcgaca uccucgucaa gggcgucgac gaguccggcg ccucccgcuu caccguccuc     1260

uuccccuccg gcaccccccu ccccgcccgc cgccagcaca cccuccaggc ccccggcucc     1320

aucuccuccg ucugccucga gcucuacgag uccgacggca agaacuccgc caaggaggag     1380

accaaguucg cccaggucgu ccuccaggac cucgacaaga aggagaacgg ccuccgcgac     1440

auccucgccg uccucaccau gaagcgcgac ggcucccucc acgucaccug caccgaccag     1500

gagaccggca agugcgaggc caucuccauc gagaucgccu ccugaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  1633
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt2)

<400>  1633
gggagaaagc uuaccauguc cgucgucggc cucgacgucg gcucccaguc cugcuacauc       60

gccgucgccc gcgccggcgg caucgagacc aucgccaacg aguucuccga ccgcugcacc      120

cccuccguca ucuccuucgg cuccaagaac cgcaccaucg gcgucgccgc caagaaccag      180

cagaucaccc acgccaacaa caccgucucc aacuucaagc gcuuccacgg ccgcgccuuc      240

aacgaccccu ucauccagaa ggagaaggag aaccucuccu acgaccucgu cccccucaag      300

aacggcggcg ucggcaucaa ggucauguac augggcgagg agcaccucuu cuccgucgag      360

cagaucaccg ccaugcuccu caccaagcuc aaggagaccg ccgagaacuc ccucaagaag      420

cccgucaccg acugcgucau cuccgucccc uccuucuuca ccgacgccga gcgccgcucc      480

guccucgacg ccgcccagau cgucggccuc aacugccucc gccucaugaa cgacaugacc      540

gccgucgccc ucaacuacgg caucuacaag caggaccucc ccucccucga cgagaagccc      600

cgcaucgucg ucuucgucga caugggccac uccgccuucc aggucuccgc cugcgccuuc      660

aacaagggca agcucaaggu ccucggcacc gccuucgacc ccuuccucgg cggcaagaac      720

uucgacgaga agcucgucga gcacuucugc gccgaguuca agaccaagua caagcucgac      780

gccaagucca agauccgcgc ccuccuccgc cucuaccagg agugcgagaa gcucaagaag      840

cucauguccu ccaacuccac cgaccucccc cucaacaucg agugcuucau gaacgacaag      900

gacgucuccg gcaagaugaa ccgcucccag uucgaggagc ucugcgccga gcuccuccag      960

aagaucgagg ucccccucua cucccuccuc gagcagaccc accucaaggu cgaggacguc     1020

uccgccgucg agaucgucgg cggcgccacc cgcauccccg ccgucaagga gcgcaucgcc     1080

aaguucuucg gcaaggacau cuccaccacc cucaacgccg acgaggccgu cgcccgcggc     1140

ugcgcccucc agugcgccau ccucuccccc gccuucaagg uccgcgaguu cuccgucacc     1200

gacgccgucc ccuuccccau cucccucauc uggaaccacg acuccgagga caccgagggc     1260

guccacgagg ucuucucccg caaccacgcc gcccccuucu ccaagguccu caccuuccuc     1320

cgccgcggcc ccuucgagcu cgaggccuuc uacuccgacc cccagggcgu ccccuacccc     1380

gaggccaaga ucggccgcuu cgucguccag aacgucuccg cccagaagga cggcgagaag     1440

ucccgcguca aggucaaggu ccgcgucaac acccacggca ucuucaccau cuccaccgcc     1500

uccauggucg agaagguccc caccgaggag aacgagaugu ccuccgaggc cgacauggag     1560

ugccucaacc agcgcccccc cgagaacccc gacaccgaca agaacgucca gcaggacaac     1620

uccgaggccg gcacccagcc ccagguccag accgacgccc agcagaccuc ccaguccccc     1680

cccucccccg agcucaccuc cgaggagaac aagauccccg acgccgacaa ggccaacgag     1740

aagaaggucg accagccccc cgaggccaag aagcccaaga ucaaggucgu caacgucgag     1800

cuccccaucg aggccaaccu cgucuggcag cucggcaagg accuccucaa cauguacauc     1860

gagaccgagg gcaagaugau caugcaggac aagcucgaga aggagcgcaa cgacgccaag     1920

aacgccgucg aggaguacgu cuacgaguuc cgcgacaagc ucugcggccc cuacgagaag     1980

uucaucugcg agcaggacca ccagaacuuc cuccgccucc ucaccgagac cgaggacugg     2040

cucuacgagg agggcgagga ccaggccaag caggccuacg ucgacaagcu cgaggagcuc     2100

augaagaucg gcacccccgu caagguccgc uuccaggagg ccgaggagcg ccccaagaug     2160

uucgaggagc ucggccagcg ccuccagcac uacgccaaga ucgccgccga cuuccgcaac     2220

aaggacgaga aguacaacca caucgacgag uccgagauga agaaggucga gaaguccguc     2280

aacgagguca uggaguggau gaacaacguc augaacgccc aggccaagaa gucccucgac     2340

caggaccccg ucguccgcgc ccaggagauc aagaccaaga ucaaggagcu caacaacacc     2400

ugcgagcccg ucgucaccca gcccaagccc aagaucgagu cccccaagcu cgagcgcacc     2460

cccaacggcc ccaacaucga caagaaggag gaggaccucg aggacaagaa caacuucggc     2520

gccgagcccc cccaccagaa cggcgagugc uaccccaacg agaagaacuc cgucaacaug     2580

gaccucgacu gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  1634
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt2)

<400>  1634
gggagaaagc uuaccauggc cgacaagguc cgccgccagc gcccccgccg ccgcgucugc       60

ugggcccucg ucgccguccu ccucgccgac cuccucgccc ucuccgacac ccucgccguc      120

auguccgucg accucggcuc cgaguccaug aaggucgcca ucgucaagcc cggcgucccc      180

auggagaucg uccucaacaa ggagucccgc cgcaagaccc ccgucaucgu cacccucaag      240

gagaacgagc gcuucuucgg cgacuccgcc gccuccaugg ccaucaagaa ccccaaggcc      300

acccuccgcu acuuccagca ccuccucggc aagcaggccg acaaccccca cgucgcccuc      360

uaccaggccc gcuuccccga gcacgagcuc accuucgacc cccagcgcca gaccguccac      420

uuccagaucu ccucccagcu ccaguucucc cccgaggagg uccucggcau gguccucaac      480

uacucccgcu cccucgccga ggacuucgcc gagcagccca ucaaggacgc cgucaucacc      540

guccccgucu ucuucaacca ggccgagcgc cgcgccgucc uccaggccgc ccgcauggcc      600

ggccucaagg uccuccagcu caucaacgac aacaccgcca ccgcccucuc cuacggcguc      660

uuccgccgca aggacaucaa caccaccgcc cagaacauca uguucuacga caugggcucc      720

ggcuccaccg ucugcaccau cgucaccuac cagaugguca agaccaagga ggccggcaug      780

cagccccagc uccagauccg cggcgucggc uucgaccgca cccucggcgg ccucgagaug      840

gagcuccgcc uccgcgagcg ccucgccggc cucuucaacg agcagcgcaa gggccagcgc      900

gccaaggacg uccgcgagaa cccccgcgcc auggccaagc uccuccgcga ggccaaccgc      960

cucaagaccg uccucuccgc caacgccgac cacauggccc agaucgaggg ccucauggac     1020

gacgucgacu ucaaggccaa ggucacccgc gucgaguucg aggagcucug cgccgaccuc     1080

uucgagcgcg uccccggccc cguccagcag gcccuccagu ccgccgagau gucccucgac     1140

gagaucgagc aggucauccu cgucggcggc gccacccgcg ucccccgcgu ccaggagguc     1200

cuccucaagg ccgucggcaa ggaggagcuc ggcaagaaca ucaacgccga cgaggccgcc     1260

gccaugggcg ccgucuacca ggccgccgcc cucuccaagg ccuucaaggu caagcccuuc     1320

gucguccgcg acgccgucgu cuaccccauc cucgucgagu ucacccgcga ggucgaggag     1380

gagcccggca uccacucccu caagcacaac aagcgcgucc ucuucucccg caugggcccc     1440

uacccccagc gcaaggucau caccuucaac cgcuacuccc acgacuucaa cuuccacauc     1500

aacuacggcg accucggcuu ccucggcccc gaggaccucc gcgucuucgg cucccagaac     1560

cucaccaccg ucaagcucaa gggcgucggc gacuccuuca agaaguaccc cgacuacgag     1620

uccaagggca ucaaggccca cuucaaccuc gacgaguccg gcguccucuc ccucgaccgc     1680

gucgaguccg ucuucgagac ccucgucgag gacuccgccg aggaggaguc cacccucacc     1740

aagcucggca acaccaucuc cucccucuuc ggcggcggca ccacccccga cgccaaggag     1800

aacggcaccg acaccgucca ggaggaggag gagucccccg ccgagggcuc caaggacgag     1860

cccggcgagc aggucgagcu caaggaggag gccgaggccc ccgucgagga cggcucccag     1920

cccccccccc ccgagcccaa gggcgacgcc acccccgagg gcgagaaggc caccgagaag     1980

gagaacggcg acaaguccga ggcccagaag cccuccgaga aggccgaggc cggccccgag     2040

ggcgucgccc ccgcccccga gggcgagaag aagcagaagc ccgcccgcaa gcgccgcaug     2100

gucgaggaga ucggcgucga gcucgucguc cucgaccucc ccgaccuccc cgaggacaag     2160

cucgcccagu ccguccagaa gcuccaggac cucacccucc gcgaccucga gaagcaggag     2220

cgcgagaagg ccgccaacuc ccucgaggcc uucaucuucg agacccagga caagcucuac     2280

cagcccgagu accaggaggu cuccaccgag gagcagcgcg aggagaucuc cggcaagcuc     2340

uccgccgccu ccaccuggcu cgaggacgag ggcgucggcg ccaccaccgu caugcucaag     2400

gagaagcucg ccgagcuccg caagcucugc cagggccucu ucuuccgcgu cgaggagcgc     2460

aagaaguggc ccgagcgccu cuccgcccuc gacaaccucc ucaaccacuc cuccauguuc     2520

cucaagggcg cccgccucau ccccgagaug gaccagaucu ucaccgaggu cgagaugacc     2580

acccucgaga aggucaucaa cgagaccugg gccuggaaga acgccacccu cgccgagcag     2640

gccaagcucc ccgccaccga gaagcccguc cuccucucca aggacaucga ggccaagaug     2700

auggcccucg accgcgaggu ccaguaccuc cucaacaagg ccaaguucac caagccccgc     2760

ccccgcccca aggacaagaa cggcacccgc gccgagcccc cccucaacgc cuccgccucc     2820

gaccagggcg agaaggucau cccccccgcc ggccagaccg aggacgccga gcccaucucc     2880

gagcccgaga aggucgagac cggcuccgag cccggcgaca ccgagccccu cgagcucggc     2940

ggccccggcg ccgagcccga gcagaaggag caguccaccg gccagaagcg cccccucaag     3000

aacgacgagc ucugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1635
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt2)

<400>  1635
gggagaaagc uuaccaugcc cgaggagacc cagacccagg accagcccau ggaggaggag       60

gaggucgaga ccuucgccuu ccaggccgag aucgcccagc ucaugucccu caucaucaac      120

accuucuacu ccaacaagga gaucuuccuc cgcgagcuca ucuccaacuc cuccgacgcc      180

cucgacaaga uccgcuacga gucccucacc gaccccucca agcucgacuc cggcaaggag      240

cuccacauca accucauccc caacaagcag gaccgcaccc ucaccaucgu cgacaccggc      300

aucggcauga ccaaggccga ccucaucaac aaccucggca ccaucgccaa guccggcacc      360

aaggccuuca uggaggcccu ccaggccggc gccgacaucu ccaugaucgg ccaguucggc      420

gucggcuucu acuccgccua ccucgucgcc gagaagguca ccgucaucac caagcacaac      480

gacgacgagc aguacgccug ggaguccucc gccggcggcu ccuucaccgu ccgcaccgac      540

accggcgagc ccaugggccg cggcaccaag gucauccucc accucaagga ggaccagacc      600

gaguaccucg aggagcgccg caucaaggag aucgucaaga agcacuccca guucaucggc      660

uaccccauca cccucuucgu cgagaaggag cgcgacaagg aggucuccga cgacgaggcc      720

gaggagaagg aggacaagga ggaggagaag gagaaggagg agaaggaguc cgaggacaag      780

cccgagaucg aggacgucgg cuccgacgag gaggaggaga agaaggacgg cgacaagaag      840

aagaagaaga agaucaagga gaaguacauc gaccaggagg agcucaacaa gaccaagccc      900

aucuggaccc gcaaccccga cgacaucacc aacgaggagu acggcgaguu cuacaagucc      960

cucaccaacg acugggagga ccaccucgcc gucaagcacu ucuccgucga gggccagcuc     1020

gaguuccgcg cccuccucuu cgucccccgc cgcgcccccu ucgaccucuu cgagaaccgc     1080

aagaagaaga acaacaucaa gcucuacguc cgccgcgucu ucaucaugga caacugcgag     1140

gagcucaucc ccgaguaccu caacuucauc cgcggcgucg ucgacuccga ggaccucccc     1200

cucaacaucu cccgcgagau gcuccagcag uccaagaucc ucaaggucau ccgcaagaac     1260

cucgucaaga agugccucga gcucuucacc gagcucgccg aggacaagga gaacuacaag     1320

aaguucuacg agcaguucuc caagaacauc aagcucggca uccacgagga cucccagaac     1380

cgcaagaagc ucuccgagcu ccuccgcuac uacaccuccg ccuccggcga cgagaugguc     1440

ucccucaagg acuacugcac ccgcaugaag gagaaccaga agcacaucua cuacaucacc     1500

ggcgagacca aggaccaggu cgccaacucc gccuucgucg agcgccuccg caagcacggc     1560

cucgagguca ucuacaugau cgagcccauc gacgaguacu gcguccagca gcucaaggag     1620

uucgagggca agacccucgu cuccgucacc aaggagggcc ucgagcuccc cgaggacgag     1680

gaggagaaga agaagcagga ggagaagaag accaaguucg agaaccucug caagaucaug     1740

aaggacaucc ucgagaagaa ggucgagaag gucgucgucu ccaaccgccu cgucaccucc     1800

cccugcugca ucgucaccuc caccuacggc uggaccgcca acauggagcg caucaugaag     1860

gcccaggccc uccgcgacaa cuccaccaug ggcuacaugg ccgccaagaa gcaccucgag     1920

aucaaccccg accacuccau caucgagacc cuccgccaga aggccgaggc cgacaagaac     1980

gacaaguccg ucaaggaccu cgucauccuc cucuacgaga ccgcccuccu cuccuccggc     2040

uucucccucg aggaccccca gacccacgcc aaccgcaucu accgcaugau caagcucggc     2100

cucggcaucg acgaggacga ccccaccgcc gacgacaccu ccgccgccgu caccgaggag     2160

augccccccc ucgagggcga cgacgacacc ucccgcaugg aggaggucga cugaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  1636
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt2)

<400>  1636
gggagaaagc uuaccaugga cuccuccaag cucgacuccg gcaagggccu ccacaucaac       60

cucgucccca acaagcagaa ccagacccuc accaucgucg acacccgcau cggcaugacc      120

aagaccgacc ucaucaacaa ccucggcacc gucaccaagu ccggcaccaa ggccuucaug      180

gaggcccucc aggccgacgc cgacaucucc augaucggcc acuucggcgu cggcuucuac      240

uccgccuacc ucgucgccaa gaaggucacc gucaucucca agcacaacaa cgacgagcag      300

uacaccuggg aguccuccgc cggcggcucc uucaccgucc gcaccgacga gugaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  1637
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt2)

<400>  1637
gggagaaagc uuaccaugcc cgaggagguc caccacggcg aggaggaggu cgagaccuuc       60

gccuuccagg ccgagaucgc ccagcucaug ucccucauca ucaacaccuu cuacuccaac      120

aaggagaucu uccuccgcga gcucaucucc aacgccuccg acgcccucga caagauccgc      180

uacgaguccc ucaccgaccc cuccaagcuc gacuccggca aggagcucaa gaucgacauc      240

auccccaacc cccaggagcg cacccucacc cucgucgaca ccggcaucgg caugaccaag      300

gccgaccuca ucaacaaccu cggcaccauc gccaaguccg gcaccaaggc cuucauggag      360

gcccuccagg ccggcgccga caucuccaug aucggccagu ucggcgucgg cuucuacucc      420

gccuaccucg ucgccgagaa ggucgucguc aucaccaagc acaacgacga cgagcaguac      480

gccugggagu ccuccgccgg cggcuccuuc accguccgcg ccgaccacgg cgagcccauc      540

ggccgcggca ccaaggucau ccuccaccuc aaggaggacc agaccgagua ccucgaggag      600

cgccgcguca aggaggucgu caagaagcac ucccaguuca ucggcuaccc caucacccuc      660

uaccucgaga aggagcgcga gaaggagauc uccgacgacg aggccgagga ggagaagggc      720

gagaaggagg aggaggacaa ggacgacgag gagaagccca agaucgagga cgucggcucc      780

gacgaggagg acgacuccgg caaggacaag aagaagaaga ccaagaagau caaggagaag      840

uacaucgacc aggaggagcu caacaagacc aagcccaucu ggacccgcaa ccccgacgac      900

aucacccagg aggaguacgg cgaguucuac aagucccuca ccaacgacug ggaggaccac      960

cucgccguca agcacuucuc cgucgagggc cagcucgagu uccgcgcccu ccucuucauc     1020

ccccgccgcg cccccuucga ccucuucgag aacaagaaga agaagaacaa caucaagcuc     1080

uacguccgcc gcgucuucau cauggacucc ugcgacgagc ucauccccga guaccucaac     1140

uucauccgcg gcgucgucga cuccgaggac cucccccuca acaucucccg cgagaugcuc     1200

cagcagucca agauccucaa ggucauccgc aagaacaucg ucaagaagug ccucgagcuc     1260

uucuccgagc ucgccgagga caaggagaac uacaagaagu ucuacgaggc cuucuccaag     1320

aaccucaagc ucggcaucca cgaggacucc accaaccgcc gccgccucuc cgagcuccuc     1380

cgcuaccaca ccucccaguc cggcgacgag augaccuccc ucuccgagua cgucucccgc     1440

augaaggaga cccagaaguc caucuacuac aucaccggcg aguccaagga gcaggucgcc     1500

aacuccgccu ucgucgagcg cguccgcaag cgcggcuucg aggucgucua caugaccgag     1560

cccaucgacg aguacugcgu ccagcagcuc aaggaguucg acggcaaguc ccucgucucc     1620

gucaccaagg agggccucga gcuccccgag gacgaggagg agaagaagaa gauggaggag     1680

uccaaggcca aguucgagaa ccucugcaag cucaugaagg agauccucga caagaagguc     1740

gagaagguca ccaucuccaa ccgccucguc uccucccccu gcugcaucgu caccuccacc     1800

uacggcugga ccgccaacau ggagcgcauc augaaggccc aggcccuccg cgacaacucc     1860

accaugggcu acaugauggc caagaagcac cucgagauca accccgacca ccccaucguc     1920

gagacccucc gccagaaggc cgaggccgac aagaacgaca aggccgucaa ggaccucguc     1980

guccuccucu ucgagaccgc ccuccucucc uccggcuucu cccucgagga cccccagacc     2040

cacuccaacc gcaucuaccg caugaucaag cucggccucg gcaucgacga ggacgagguc     2100

gccgccgagg agcccaacgc cgccgucccc gacgagaucc ccccccucga gggcgacgag     2160

gacgccuccc gcauggagga ggucgacuga ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  1638
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt2)

<400>  1638
gggagaaagc uuaccaugcg cgcccucugg guccucggcc ucugcugcgu ccuccucacc       60

uucggcuccg uccgcgccga cgacgagguc gacgucgacg gcaccgucga ggaggaccuc      120

ggcaaguccc gcgagggcuc ccgcaccgac gacgaggucg uccagcgcga ggaggaggcc      180

auccagcucg acggccucaa cgccucccag auccgcgagc uccgcgagaa guccgagaag      240

uucgccuucc aggccgaggu caaccgcaug augaagcuca ucaucaacuc ccucuacaag      300

aacaaggaga ucuuccuccg cgagcucauc uccaacgccu ccgacgcccu cgacaagauc      360

cgccucaucu cccucaccga cgagaacgcc cucuccggca acgaggagcu caccgucaag      420

aucaagugcg acaaggagaa gaaccuccuc cacgucaccg acaccggcgu cggcaugacc      480

cgcgaggagc ucgucaagaa ccucggcacc aucgccaagu ccggcaccuc cgaguuccuc      540

aacaagauga ccgaggccca ggaggacggc caguccaccu ccgagcucau cggccaguuc      600

ggcgucggcu ucuacuccgc cuuccucguc gccgacaagg ucaucgucac cuccaagcac      660

aacaacgaca cccagcacau cugggagucc gacuccaacg aguucuccgu caucgccgac      720

ccccgcggca acacccucgg ccgcggcacc accaucaccc ucguccucaa ggaggaggcc      780

uccgacuacc ucgagcucga caccaucaag aaccucguca agaaguacuc ccaguucauc      840

aacuucccca ucuacgucug guccuccaag accgagaccg ucgaggagcc cauggaggag      900

gaggaggccg ccaaggagga gaaggaggag uccgacgacg aggccgccgu cgaggaggag      960

gaggaggaga agaagcccaa gaccaagaag gucgagaaga ccgucuggga cugggagcuc     1020

augaacgaca ucaagcccau cuggcagcgc cccuccaagg aggucgagga ggacgaguac     1080

aaggccuucu acaaguccuu cuccaaggag uccgacgacc ccauggccua cauccacuuc     1140

accgccgagg gcgaggucac cuucaagucc auccucuucg uccccaccuc cgccccccgc     1200

ggccucuucg acgaguacgg cuccaagaag uccgacuaca ucaagcucua cguccgccgc     1260

gucuucauca ccgacgacuu ccacgacaug augcccaagu accucaacuu cgucaagggc     1320

gucgucgacu ccgacgaccu cccccucaac gucucccgcg agacccucca gcagcacaag     1380

cuccucaagg ucauccgcaa gaagcucguc cgcaagaccc ucgacaugau caagaagauc     1440

gccgacgaca aguacaacga caccuucugg aaggaguucg gcaccaacau caagcucggc     1500

gucaucgagg accacuccaa ccgcacccgc cucgccaagc uccuccgcuu ccaguccucc     1560

caccacccca ccgacaucac cucccucgac caguacgucg agcgcaugaa ggagaagcag     1620

gacaagaucu acuucauggc cggcuccucc cgcaaggagg ccgaguccuc ccccuucguc     1680

gagcgccucc ucaagaaggg cuacgagguc aucuaccuca ccgagcccgu cgacgaguac     1740

ugcauccagg cccuccccga guucgacggc aagcgcuucc agaacgucgc caaggagggc     1800

gucaaguucg acgaguccga gaagaccaag gagucccgcg aggccgucga gaaggaguuc     1860

gagccccucc ucaacuggau gaaggacaag gcccucaagg acaagaucga gaaggccguc     1920

gucucccagc gccucaccga gucccccugc gcccucgucg ccucccagua cggcuggucc     1980

ggcaacaugg agcgcaucau gaaggcccag gccuaccaga ccggcaagga caucuccacc     2040

aacuacuacg ccucccagaa gaagaccuuc gagaucaacc cccgccaccc ccucauccgc     2100

gacaugcucc gccgcaucaa ggaggacgag gacgacaaga ccguccucga ccucgccguc     2160

guccucuucg agaccgccac ccuccgcucc ggcuaccucc uccccgacac caaggccuac     2220

ggcgaccgca ucgagcgcau gcuccgccuc ucccucaaca ucgaccccga cgccaagguc     2280

gaggaggagc ccgaggagga gcccgaggag accgccgagg acaccaccga ggacaccgag     2340

caggacgagg acgaggagau ggacgucggc accgacgagg aggaggagac cgccaaggag     2400

uccaccgccg agaaggacga gcucugagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  1639
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt2)

<400>  1639
gggagaaagc uuaccauggc ccgcgagcuc cgcgcccucc uccucugggg ccgccgccuc       60

cgcccccucc uccgcgcccc cgcccucgcc gccguccccg gcggcaagcc cauccucugc      120

ccccgccgca ccaccgccca gcucggcccc cgccgcaacc ccgccugguc ccuccaggcc      180

ggccgccucu ucuccaccca gaccgccgag gacaaggagg agccccucca cuccaucauc      240

uccuccaccg aguccgucca gggcuccacc uccaagcacg aguuccaggc cgagaccaag      300

aagcuccucg acaucgucgc ccgcucccuc uacuccgaga aggaggucuu cauccgcgag      360

cucaucucca acgccuccga cgcccucgag aagcuccgcc acaagcucgu cuccgacggc      420

caggcccucc ccgagaugga gauccaccuc cagaccaacg ccgagaaggg caccaucacc      480

auccaggaca ccggcaucgg caugacccag gaggagcucg ucuccaaccu cggcaccauc      540

gcccgcuccg gcuccaaggc cuuccucgac gcccuccaga accaggccga ggccuccucc      600

aagaucaucg gccaguucgg cgucggcuuc uacuccgccu ucauggucgc cgaccgcguc      660

gaggucuacu cccgcuccgc cgcccccggc ucccucggcu accaguggcu cuccgacggc      720

uccggcgucu ucgagaucgc cgaggccucc ggcguccgca ccggcaccaa gaucaucauc      780

caccucaagu ccgacugcaa ggaguucucc uccgaggccc gcguccgcga cgucgucacc      840

aaguacucca acuucgucuc cuucccccuc uaccucaacg gccgccgcau gaacacccuc      900

caggccaucu ggaugaugga ccccaaggac guccgcgagu ggcagcacga ggaguucuac      960

cgcuacgucg cccaggccca cgacaagccc cgcuacaccc uccacuacaa gaccgacgcc     1020

ccccucaaca uccgcuccau cuucuacguc cccgacauga agcccuccau guucgacguc     1080

ucccgcgagc ucggcuccuc cgucgcccuc uacucccgca agguccucau ccagaccaag     1140

gccaccgaca uccuccccaa guggcuccgc uucauccgcg gcgucgucga cuccgaggac     1200

aucccccuca accucucccg cgagcuccuc caggaguccg cccucauccg caagcuccgc     1260

gacguccucc agcagcgccu caucaaguuc uucaucgacc aguccaagaa ggacgccgag     1320

aaguacgcca aguucuucga ggacuacggc cucuucaugc gcgagggcau cgucaccgcc     1380

accgagcagg aggucaagga ggacaucgcc aagcuccucc gcuacgaguc cuccgcccuc     1440

cccuccggcc agcucaccuc ccucuccgag uacgccuccc gcaugcgcgc cggcacccgc     1500

aacaucuacu accucugcgc ccccaaccgc caccucgccg agcacucccc cuacuacgag     1560

gccaugaaga agaaggacac cgagguccuc uucugcuucg agcaguucga cgagcucacc     1620

cuccuccacc uccgcgaguu cgacaagaag aagcucaucu ccgucgagac cgacaucguc     1680

gucgaccacu acaaggagga gaaguucgag gaccgcuccc ccgccgccga gugccucucc     1740

gagaaggaga ccgaggagcu cauggccugg augcgcaacg uccucggcuc ccgcgucacc     1800

aacgucaagg ucacccuccg ccucgacacc caccccgcca uggucaccgu ccucgagaug     1860

ggcgccgccc gccacuuccu ccgcaugcag cagcucgcca agacccagga ggagcgcgcc     1920

cagcuccucc agcccacccu cgagaucaac ccccgccacg cccucaucaa gaagcucaac     1980

cagcuccgcg ccuccgagcc cggccucgcc cagcuccucg ucgaccagau cuacgagaac     2040

gccaugaucg ccgccggccu cgucgacgac ccccgcgcca uggucggccg ccucaacgag     2100

cuccucguca aggcccucga gcgccacuga ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  1640
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt2)

<400>  1640
gggagaaagc uuaccauggg caagaucucc ucccucccca cccagcucuu caagugcugc       60

uucugcgacu uccucaaggu caagaugcac accauguccu ccucccaccu cuucuaccuc      120

gcccucugcc uccucaccuu caccuccucc gccaccgccg gccccgagac ccucugcggc      180

gccgagcucg ucgacgcccu ccaguucguc ugcggcgacc gcggcuucua cuucaacaag      240

cccaccggcu acggcuccuc cucccgccgc gccccccaga ccggcaucgu cgacgagugc      300

ugcuuccgcu ccugcgaccu ccgccgccuc gagauguacu gcgccccccu caagcccgcc      360

aaguccgccc gcuccguccg cgcccagcgc cacaccgaca ugcccaagac ccagaaggag      420

guccaccuca agaacgccuc ccgcggcucc gccggcaaca agaacuaccg caugugagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  1641
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt2)

<400>  1641
gggagaaagc uuaccauggg cauccccaug ggcaagucca ugcucguccu ccucaccuuc       60

cucgccuucg ccuccugcug caucgccgcc uaccgccccu ccgagacccu cugcggcggc      120

gagcucgucg acacccucca guucgucugc ggcgaccgcg gcuucuacuu cucccgcccc      180

gccucccgcg ucucccgccg cucccgcggc aucgucgagg agugcugcuu ccgcuccugc      240

gaccucgccc uccucgagac cuacugcgcc acccccgcca aguccgagcg cgacgucucc      300

acccccccca ccguccuccc cgacaacuuc ccccgcuacc ccgucggcaa guucuuccag      360

uacgacaccu ggaagcaguc cacccagcgc cuccgccgcg gccuccccgc ccuccuccgc      420

gcccgccgcg gccacguccu cgccaaggag cucgaggccu uccgcgaggc caagcgccac      480

cgcccccuca ucgcccuccc cacccaggac cccgcccacg gcggcgcccc ccccgagaug      540

gccuccaacc gcaagugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  1642
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt2)

<400>  1642
gggagaaagc uuaccaugaa cuccuucucc accuccgccu ucggccccgu cgccuucucc       60

cucggccucc uccucguccu ccccgccgcc uuccccgccc ccgucccccc cggcgaggac      120

uccaaggacg ucgccgcccc ccaccgccag ccccucaccu ccuccgagcg caucgacaag      180

cagauccgcu acauccucga cggcaucucc gcccuccgca aggagaccug caacaagucc      240

aacaugugcg aguccuccaa ggaggcccuc gccgagaaca accucaaccu ccccaagaug      300

gccgagaagg acggcugcuu ccaguccggc uucaacgagg agaccugccu cgucaagauc      360

aucaccggcc uccucgaguu cgaggucuac cucgaguacc uccagaaccg cuucgagucc      420

uccgaggagc aggcccgcgc cguccagaug uccaccaagg uccucaucca guuccuccag      480

aagaaggcca agaaccucga cgccaucacc acccccgacc ccaccaccaa cgccucccuc      540

cucaccaagc uccaggccca gaaccagugg cuccaggaca ugaccaccca ccucauccuc      600

cgcuccuuca aggaguuccu ccaguccucc cuccgcgccc uccgccagau gugaggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  1643
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt2)

<400>  1643
gggagaaagc uuaccaugcc ccuccucugg cuccgcggcu uccuccucgc cuccugcugg       60

aucaucgucc gcuccucccc cacccccggc uccgagggcc acuccgccgc ccccgacugc      120

cccuccugcg cccucgccgc ccuccccaag gacgucccca acucccagcc cgagaugguc      180

gaggccguca agaagcacau ccucaacaug cuccaccuca agaagcgccc cgacgucacc      240

cagcccgucc ccaaggccgc ccuccucaac gccauccgca agcuccacgu cggcaagguc      300

ggcgagaacg gcuacgucga gaucgaggac gacaucggcc gccgcgccga gaugaacgag      360

cucauggagc agaccuccga gaucaucacc uucgccgagu ccggcaccgc ccgcaagacc      420

cuccacuucg agaucuccaa ggagggcucc gaccucuccg ucgucgagcg cgccgagguc      480

uggcucuucc ucaagguccc caaggccaac cgcacccgca ccaaggucac cauccgccuc      540

uuccagcagc agaagcaccc ccagggcucc cucgacaccg gcgaggaggc cgaggagguc      600

ggccucaagg gcgagcgcuc cgagcuccuc cucuccgaga aggucgucga cgcccgcaag      660

uccaccuggc acgucuuccc cgucuccucc uccauccagc gccuccucga ccagggcaag      720

uccucccucg acguccgcau cgccugcgag cagugccagg aguccggcgc cucccucguc      780

cuccucggca agaagaagaa gaaggaggag gagggcgagg gcaagaagaa gggcggcggc      840

gagggcggcg ccggcgccga cgaggagaag gagcaguccc accgccccuu ccucaugcuc      900

caggcccgcc aguccgagga ccacccccac cgccgccgcc gccgcggccu cgagugcgac      960

ggcaagguca acaucugcug caagaagcag uucuucgucu ccuucaagga caucggcugg     1020

aacgacugga ucaucgcccc cuccggcuac cacgccaacu acugcgaggg cgagugcccc     1080

ucccacaucg ccggcaccuc cggcuccucc cucuccuucc acuccaccgu caucaaccac     1140

uaccgcaugc gcggccacuc ccccuucgcc aaccucaagu ccugcugcgu ccccaccaag     1200

cuccgcccca uguccaugcu cuacuacgac gacggccaga acaucaucaa gaaggacauc     1260

cagaacauga ucgucgagga gugcggcugc uccugaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  1644
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt2)

<400>  1644
gggagaaagc uuaccaugga cggccucccc ggccgcgccc ucggcgccgc cugccuccuc       60

cuccucgccg ccggcuggcu cggccccgag gccuggggcu cccccacccc cccccccacc      120

cccgccgccc cccccccccc cccccccccc ggcucccccg gcggcuccca ggacaccugc      180

accuccugcg gcggcuuccg ccgccccgag gagcucggcc gcgucgacgg cgacuuccuc      240

gaggccguca agcgccacau ccucucccgc cuccagaugc gcggccgccc caacaucacc      300

cacgccgucc ccaaggccgc cauggucacc gcccuccgca agcuccacgc cggcaagguc      360

cgcgaggacg gccgcgucga gaucccccac cucgacggcc acgccucccc cggcgccgac      420

ggccaggagc gcgucuccga gaucaucucc uucgccgaga ccgacggccu cgccuccucc      480

cgcguccgcc ucuacuucuu caucuccaac gagggcaacc agaaccucuu cgucguccag      540

gccucccucu ggcucuaccu caagcuccuc cccuacgucc ucgagaaggg cucccgccgc      600

aagguccgcg ucaaggucua cuuccaggag cagggccacg gcgaccgcug gaacaugguc      660

gagaagcgcg ucgaccucaa gcgcuccggc uggcacaccu ucccccucac cgaggccauc      720

caggcccucu ucgagcgcgg cgagcgccgc cucaaccucg acguccagug cgacuccugc      780

caggagcucg ccgucguccc cgucuucguc gaccccggcg aggaguccca ccgccccuuc      840

gucgucgucc aggcccgccu cggcgacucc cgccaccgca uccgcaagcg cggccucgag      900

ugcgacggcc gcaccaaccu cugcugccgc cagcaguucu ucaucgacuu ccgccucauc      960

ggcuggaacg acuggaucau cgcccccacc ggcuacuacg gcaacuacug cgagggcucc     1020

ugccccgccu accucgccgg cguccccggc uccgccuccu ccuuccacac cgccgucguc     1080

aaccaguacc gcaugcgcgg ccucaacccc ggcaccguca acuccugcug cauccccacc     1140

aagcucucca ccauguccau gcucuacuuc gacgacgagu acaacaucgu caagcgcgac     1200

guccccaaca ugaucgucga ggagugcggc ugcgccugag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  1645
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt2)

<400>  1645
gggagaaagc uuaccauggc ccuccgcguc cuccuccuca ccgcccucac ccucugccac       60

ggcuucaacc ucgacaccga gaacgccaug accuuccagg agaacgcccg cggcuucggc      120

caguccgucg uccagcucca gggcucccgc gucgucgucg gcgcccccca ggagaucguc      180

gccgccaacc agcgcggcuc ccucuaccag ugcgacuacu ccaccggcuc cugcgagccc      240

auccgccucc agguccccgu cgaggccguc aacauguccc ucggccucuc ccucgccgcc      300

accaccuccc ccccccagcu ccucgccugc ggccccaccg uccaccagac cugcuccgag      360

aacaccuacg ucaagggccu cugcuuccuc uucggcucca accuccgcca gcagccccag      420

aaguuccccg aggcccuccg cggcugcccc caggaggacu ccgacaucgc cuuccucauc      480

gacggcuccg gcuccaucau cccccacgac uuccgccgca ugaaggaguu cgucuccacc      540

gucauggagc agcucaagaa guccaagacc cucuucuccc ucaugcagua cuccgaggag      600

uuccgcaucc acuucaccuu caaggaguuc cagaacaacc ccaacccccg cucccucguc      660

aagcccauca cccagcuccu cggccgcacc cacaccgcca ccggcauccg caaggucguc      720

cgcgagcucu ucaacaucac caacggcgcc cgcaagaacg ccuucaagau ccucgucguc      780

aucaccgacg gcgagaaguu cggcgacccc cucggcuacg aggacgucau ccccgaggcc      840

gaccgcgagg gcgucauccg cuacgucauc ggcgucggcg acgccuuccg cuccgagaag      900

ucccgccagg agcucaacac caucgccucc aagccccccc gcgaccacgu cuuccagguc      960

aacaacuucg aggcccucaa gaccauccag aaccagcucc gcgagaagau cuucgccauc     1020

gagggcaccc agaccggcuc cuccuccucc uucgagcacg agauguccca ggagggcuuc     1080

uccgccgcca ucaccuccaa cggcccccuc cucuccaccg ucggcuccua cgacugggcc     1140

ggcggcgucu uccucuacac cuccaaggag aaguccaccu ucaucaacau gacccgcguc     1200

gacuccgaca ugaacgacgc cuaccucggc uacgccgccg ccaucauccu ccgcaaccgc     1260

guccaguccc ucguccucgg cgccccccgc uaccagcaca ucggccucgu cgccauguuc     1320

cgccagaaca ccggcaugug ggaguccaac gccaacguca agggcaccca gaucggcgcc     1380

uacuucggcg ccucccucug cuccgucgac gucgacucca acggcuccac cgaccucguc     1440

cucaucggcg ccccccacua cuacgagcag acccgcggcg gccaggucuc cgucugcccc     1500

cucccccgcg gccgcgcccg cuggcagugc gacgccgucc ucuacggcga gcagggccag     1560

cccuggggcc gcuucggcgc cgcccucacc guccucggcg acgucaacgg cgacaagcuc     1620

accgacgucg ccaucggcgc ccccggcgag gaggacaacc gcggcgccgu cuaccucuuc     1680

cacggcaccu ccggcuccgg caucuccccc ucccacuccc agcgcaucgc cggcuccaag     1740

cucucccccc gccuccagua cuucggccag ucccucuccg gcggccagga ccucaccaug     1800

gacggccucg ucgaccucac cgucggcgcc cagggccacg uccuccuccu ccgcucccag     1860

cccguccucc gcgucaaggc caucauggag uucaaccccc gcgaggucgc ccgcaacguc     1920

uucgagugca acgaccaggu cgucaagggc aaggaggccg gcgagguccg cgucugccuc     1980

cacguccaga aguccacccg cgaccgccuc cgcgagggcc agauccaguc cgucgucacc     2040

uacgaccucg cccucgacuc cggccgcccc cacucccgcg ccgucuucaa cgagaccaag     2100

aacuccaccc gccgccagac ccagguccuc ggccucaccc agaccugcga gacccucaag     2160

cuccagcucc ccaacugcau cgaggacccc gucuccccca ucguccuccg ccucaacuuc     2220

ucccucgucg gcaccccccu cuccgccuuc ggcaaccucc gccccguccu cgccgaggac     2280

gcccagcgcc ucuucaccgc ccucuucccc uucgagaaga acugcggcaa cgacaacauc     2340

ugccaggacg accucuccau caccuucucc uucauguccc ucgacugccu cgucgucggc     2400

ggcccccgcg aguucaacgu caccgucacc guccgcaacg acggcgagga cuccuaccgc     2460

acccagguca ccuucuucuu cccccucgac cucuccuacc gcaaggucuc cacccuccag     2520

aaccagcgcu cccagcgcuc cuggcgccuc gccugcgagu ccgccuccuc caccgagguc     2580

uccggcgccc ucaaguccac cuccugcucc aucaaccacc ccaucuuccc cgagaacucc     2640

gaggucaccu ucaacaucac cuucgacguc gacuccaagg ccucccucgg caacaagcuc     2700

cuccucaagg ccaacgucac cuccgagaac aacaugcccc gcaccaacaa gaccgaguuc     2760

cagcucgagc uccccgucaa guacgccguc uacauggucg ucaccuccca cggcgucucc     2820

accaaguacc ucaacuucac cgccuccgag aacaccuccc gcgucaugca gcaccaguac     2880

caggucucca accucggcca gcgcucccuc cccaucuccc ucgucuuccu cguccccguc     2940

cgccucaacc agaccgucau cugggaccgc ccccagguca ccuucuccga gaaccucucc     3000

uccaccugcc acaccaagga gcgccucccc ucccacuccg acuuccucgc cgagcuccgc     3060

aaggcccccg ucgucaacug cuccaucgcc gucugccagc gcauccagug cgacaucccc     3120

uucuucggca uccaggagga guucaacgcc acccucaagg gcaaccucuc cuucgacugg     3180

uacaucaaga ccucccacaa ccaccuccuc aucgucucca ccgccgagau ccucuucaac     3240

gacuccgucu ucacccuccu ccccggccag ggcgccuucg uccgcuccca gaccgagacc     3300

aaggucgagc ccuucgaggu ccccaacccc cucccccuca ucgucggcuc cuccgucggc     3360

ggccuccucc uccucgcccu caucaccgcc gcccucuaca agcucggcuu cuucaagcgc     3420

caguacaagg acaugauguc cgagggcggc ccccccggcg ccgagcccca gugaggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  1646
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt2)

<400>  1646
gggagaaagc uuaccauguu cucccucaag acccuccccu uccuccuccu ccuccacguc       60

cagaucucca aggccuuccc cgucuccucc aaggagaaga acaccaagac cguccaggac      120

uaccucgaga aguucuacca gcuccccucc aaccaguacc aguccacccg caagaacggc      180

accaacguca ucgucgagaa gcucaaggag augcagcgcu ucuucggccu caacgucacc      240

ggcaagccca acgaggagac ccucgacaug augaagaagc cccgcugcgg cguccccgac      300

uccggcggcu ucaugcucac ccccggcaac cccaaguggg agcgcaccaa ccucaccuac      360

cgcauccgca acuacacccc ccagcucucc gaggccgagg ucgagcgcgc caucaaggac      420

gccuucgagc ucugguccgu cgccuccccc cucaucuuca cccgcaucuc ccagggcgag      480

gccgacauca acaucgccuu cuaccagcgc gaccacggcg acaacucccc cuucgacggc      540

cccaacggca uccucgccca cgccuuccag cccggccagg gcaucggcgg cgacgcccac      600

uucgacgccg aggagaccug gaccaacacc uccgccaacu acaaccucuu ccucgucgcc      660

gcccacgagu ucggccacuc ccucggccuc gcccacuccu ccgaccccgg cgcccucaug      720

uaccccaacu acgccuuccg cgagaccucc aacuacuccc ucccccagga cgacaucgac      780

ggcauccagg ccaucuacgg ccucuccucc aaccccaucc agcccaccgg ccccuccacc      840

cccaagcccu gcgaccccuc ccucaccuuc gacgccauca ccacccuccg cggcgagauc      900

cucuucuuca aggaccgcua cuucuggcgc cgccaccccc agcuccagcg cgucgagaug      960

aacuucaucu cccucuucug gcccucccuc cccaccggca uccaggccgc cuacgaggac     1020

uucgaccgcg accucaucuu ccucuucaag ggcaaccagu acugggcccu cuccggcuac     1080

gacauccucc agggcuaccc caaggacauc uccaacuacg gcuuccccuc cuccguccag     1140

gccaucgacg ccgccgucuu cuaccgcucc aagaccuacu ucuucgucaa cgaccaguuc     1200

uggcgcuacg acaaccagcg ccaguucaug gagcccggcu accccaaguc caucuccggc     1260

gccuuccccg gcaucgaguc caaggucgac gccgucuucc agcaggagca cuucuuccac     1320

gucuucuccg gcccccgcua cuacgccuuc gaccucaucg cccagcgcgu cacccgcguc     1380

gcccgcggca acaaguggcu caacugccgc uacggcugag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  1647
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt2)

<400>  1647
gggagaaagc uuaccauguc ccucuggcag ccccucgucc ucguccuccu cguccucggc       60

ugcugcuucg ccgccccccg ccagcgccag uccacccucg uccucuuccc cggcgaccuc      120

cgcaccaacc ucaccgaccg ccagcucgcc gaggaguacc ucuaccgcua cggcuacacc      180

cgcgucgccg agaugcgcgg cgaguccaag ucccucggcc ccgcccuccu ccuccuccag      240

aagcagcucu cccuccccga gaccggcgag cucgacuccg ccacccucaa ggccaugcgc      300

accccccgcu gcggcguccc cgaccucggc cgcuuccaga ccuucgaggg cgaccucaag      360

uggcaccacc acaacaucac cuacuggauc cagaacuacu ccgaggaccu cccccgcgcc      420

gucaucgacg acgccuucgc ccgcgccuuc gcccucuggu ccgccgucac cccccucacc      480

uucacccgcg ucuacucccg cgacgccgac aucgucaucc aguucggcgu cgccgagcac      540

ggcgacggcu accccuucga cggcaaggac ggccuccucg cccacgccuu cccccccggc      600

cccggcaucc agggcgacgc ccacuucgac gacgacgagc ucuggucccu cggcaagggc      660

gucgucgucc ccacccgcuu cggcaacgcc gacggcgccg ccugccacuu ccccuucauc      720

uucgagggcc gcuccuacuc cgccugcacc accgacggcc gcuccgacgg ccuccccugg      780

ugcuccacca ccgccaacua cgacaccgac gaccgcuucg gcuucugccc cuccgagcgc      840

cucuacaccc aggacggcaa cgccgacggc aagcccugcc aguuccccuu caucuuccag      900

ggccaguccu acuccgccug caccaccgac ggccgcuccg acggcuaccg cuggugcgcc      960

accaccgcca acuacgaccg cgacaagcuc uucggcuucu gccccacccg cgccgacucc     1020

accgucaugg gcggcaacuc cgccggcgag cucugcgucu uccccuucac cuuccucggc     1080

aaggaguacu ccaccugcac cuccgagggc cgcggcgacg gccgccucug gugcgccacc     1140

accuccaacu ucgacuccga caagaagugg ggcuucugcc ccgaccaggg cuacucccuc     1200

uuccucgucg ccgcccacga guucggccac gcccucggcc ucgaccacuc cuccgucccc     1260

gaggcccuca uguaccccau guaccgcuuc accgagggcc ccccccucca caaggacgac     1320

gucaacggca uccgccaccu cuacggcccc cgccccgagc ccgagccccg cccccccacc     1380

accaccaccc cccagcccac cgcccccccc accgucugcc ccaccggccc ccccaccguc     1440

caccccuccg agcgccccac cgccggcccc accggccccc ccuccgccgg ccccaccggc     1500

ccccccaccg ccggccccuc caccgccacc accguccccc ucucccccgu cgacgacgcc     1560

ugcaacguca acaucuucga cgccaucgcc gagaucggca accagcucua ccucuucaag     1620

gacggcaagu acuggcgcuu cuccgagggc cgcggcuccc gcccccaggg ccccuuccuc     1680

aucgccgaca aguggcccgc ccucccccgc aagcucgacu ccgucuucga ggagcgccuc     1740

uccaagaagc ucuucuucuu cuccggccgc caggucuggg ucuacaccgg cgccuccguc     1800

cucggccccc gccgccucga caagcucggc cucggcgccg acgucgccca ggucaccggc     1860

gcccuccgcu ccggccgcgg caagaugcuc cucuucuccg gccgccgccu cuggcgcuuc     1920

gacgucaagg cccagauggu cgacccccgc uccgccuccg aggucgaccg cauguucccc     1980

ggcguccccc ucgacaccca cgacgucuuc caguaccgcg agaaggccua cuucugccag     2040

gaccgcuucu acuggcgcgu cuccucccgc uccgagcuca accaggucga ccaggucggc     2100

uacgucaccu acgacauccu ccagugcccc gaggacugag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  1648
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt2)

<400>  1648
gggagaaagc uuaccaugca ccccggcguc cucgccgccu uccucuuccu cuccuggacc       60

cacugccgcg cccucccccu ccccuccggc ggcgacgagg acgaccucuc cgaggaggac      120

cuccaguucg ccgagcgcua ccuccgcucc uacuaccacc ccaccaaccu cgccggcauc      180

cucaaggaga acgccgccuc cuccaugacc gagcgccucc gcgagaugca guccuucuuc      240

ggccucgagg ucaccggcaa gcucgacgac aacacccucg acgucaugaa gaagccccgc      300

ugcggcgucc ccgacgucgg cgaguacaac gucuuccccc gcacccucaa gugguccaag      360

augaaccuca ccuaccgcau cgucaacuac acccccgaca ugacccacuc cgaggucgag      420

aaggccuuca agaaggccuu caaggucugg uccgacguca ccccccucaa cuucacccgc      480

cuccacgacg gcaucgccga caucaugauc uccuucggca ucaaggagca cggcgacuuc      540

uaccccuucg acggccccuc cggccuccuc gcccacgccu ucccccccgg ccccaacuac      600

ggcggcgacg cccacuucga cgacgacgag accuggaccu ccuccuccaa gggcuacaac      660

cucuuccucg ucgccgccca cgaguucggc cacucccucg gccucgacca cuccaaggac      720

cccggcgccc ucauguuccc caucuacacc uacaccggca agucccacuu caugcucccc      780

gacgacgacg uccagggcau ccagucccuc uacggccccg gcgacgagga ccccaacccc      840

aagcacccca agacccccga caagugcgac cccucccucu cccucgacgc caucaccucc      900

cuccgcggcg agaccaugau cuucaaggac cgcuucuucu ggcgccucca cccccagcag      960

gucgacgccg agcucuuccu caccaagucc uucuggcccg agcuccccaa ccgcaucgac     1020

gccgccuacg agcaccccuc ccacgaccuc aucuucaucu uccgcggccg caaguucugg     1080

gcccucaacg gcuacgacau ccucgagggc uaccccaaga agaucuccga gcucggccuc     1140

cccaaggagg ucaagaagau cuccgccgcc guccacuucg aggacaccgg caagacccuc     1200

cucuucuccg gcaaccaggu cuggcgcuac gacgacacca accacaucau ggacaaggac     1260

uacccccgcc ucaucgagga ggacuucccc ggcaucggcg acaaggucga cgccgucuac     1320

gagaagaacg gcuacaucua cuucuucaac ggccccaucc aguucgagua cuccaucugg     1380

uccaaccgca ucguccgcgu caugcccgcc aacuccaucc ucuggugcug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  1649
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt2)

<400>  1649
gggagaaagc uuaccaugga gacccccaac accaccgagg acuacgacac caccaccgag       60

uucgacuacg gcgacgccac ccccugccag aaggucaacg agcgcgccuu cggcgcccag      120

cuccuccccc cccucuacuc ccucgucuuc gucaucggcc ucgucggcaa cauccucguc      180

guccucgucc ucguccagua caagcgccuc aagaacauga ccuccaucua ccuccucaac      240

cucgccaucu ccgaccuccu cuuccucuuc acccuccccu ucuggaucga cuacaagcuc      300

aaggacgacu gggucuucgg cgacgccaug ugcaagaucc ucuccggcuu cuacuacacc      360

ggccucuacu ccgagaucuu cuucaucauc cuccucacca ucgaccgcua ccucgccauc      420

guccacgccg ucuucgcccu ccgcgcccgc accgucaccu ucggcgucau caccuccauc      480

aucaucuggg cccucgccau ccucgccucc augcccggcc ucuacuucuc caagacccag      540

ugggaguuca cccaccacac cugcucccuc cacuuccccc acgagucccu ccgcgagugg      600

aagcucuucc aggcccucaa gcucaaccuc uucggccucg uccucccccu ccucgucaug      660

aucaucugcu acaccggcau caucaagauc cuccuccgcc gccccaacga gaagaagucc      720

aaggccgucc gccucaucuu cgucaucaug aucaucuucu uccucuucug gacccccuac      780

aaccucacca uccucaucuc cgucuuccag gacuuccucu ucacccacga gugcgagcag      840

ucccgccacc ucgaccucgc cguccagguc accgagguca ucgccuacac ccacugcugc      900

gucaaccccg ucaucuacgc cuucgucggc gagcgcuucc gcaaguaccu ccgccagcuc      960

uuccaccgcc gcgucgccgu ccaccucguc aaguggcucc ccuuccucuc cgucgaccgc     1020

cucgagcgcg ucuccuccac cucccccucc accggcgagc acgagcucuc cgccggcuuc     1080

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  1650
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt2)

<400>  1650
gggagaaagc uuaccaugcg cacccucgcc ugccuccucc uccucggcug cggcuaccuc       60

gcccacgucc ucgccgagga ggccgagauc ccccgcgagg ucaucgagcg ccucgcccgc      120

ucccagaucc acuccauccg cgaccuccag cgccuccucg agaucgacuc cgucggcucc      180

gaggacuccc ucgacaccuc ccuccgcgcc cacggcgucc acgccaccaa gcacgucccc      240

gagaagcgcc cccuccccau ccgccgcaag cgcuccaucg aggaggccgu ccccgccguc      300

ugcaagaccc gcaccgucau cuacgagauc ccccgcuccc aggucgaccc caccuccgcc      360

aacuuccuca ucuggccccc cugcgucgag gucaagcgcu gcaccggcug cugcaacacc      420

uccuccguca agugccagcc cucccgcguc caccaccgcu ccgucaaggu cgccaagguc      480

gaguacgucc gcaagaagcc caagcucaag gagguccagg uccgccucga ggagcaccuc      540

gagugcgccu gcgccaccac cucccucaac cccgacuacc gcgaggagga caccggccgc      600

ccccgcgagu ccggcaagaa gcgcaagcgc aagcgccuca agcccaccug aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  1651
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt2)

<400>  1651
gggagaaagc uuaccaugaa ccgcugcugg gcccucuucc ucucccucug cugcuaccuc       60

cgccucgucu ccgccgaggg cgaccccauc cccgaggagc ucuacgagau gcucuccgac      120

cacuccaucc gcuccuucga cgaccuccag cgccuccucc acggcgaccc cggcgaggag      180

gacggcgccg agcucgaccu caacaugacc cgcucccacu ccggcggcga gcucgagucc      240

cucgcccgcg gccgccgcuc ccucggcucc cucaccaucg ccgagcccgc caugaucgcc      300

gagugcaaga cccgcaccga ggucuucgag aucucccgcc gccucaucga ccgcaccaac      360

gccaacuucc ucgucuggcc ccccugcguc gagguccagc gcugcuccgg cugcugcaac      420

aaccgcaacg uccagugccg ccccacccag guccagcucc gccccgucca gguccgcaag      480

aucgagaucg uccgcaagaa gcccaucuuc aagaaggcca ccgucacccu cgaggaccac      540

cucgccugca agugcgagac cgucgccgcc gcccgccccg ucacccgcuc ccccggcggc      600

ucccaggagc agcgcgccaa gaccccccag acccgcguca ccauccgcac cguccgcguc      660

cgccgccccc ccaagggcaa gcaccgcaag uucaagcaca cccacgacaa gaccgcccuc      720

aaggagaccc ucggcgccug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  1652
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt2)

<400>  1652
gggagaaagc uuaccauguc ccucuucggc cuccuccucc ucaccuccgc ccucgccggc       60

cagcgccagg gcacccaggc cgaguccaac cucuccucca aguuccaguu cuccuccaac      120

aaggagcaga acggcgucca ggacccccag cacgagcgca ucaucaccgu cuccaccaac      180

ggcuccaucc acuccccccg cuucccccac accuaccccc gcaacaccgu ccucgucugg      240

cgccucgucg ccgucgagga gaacgucugg auccagcuca ccuucgacga gcgcuucggc      300

cucgaggacc ccgaggacga caucugcaag uacgacuucg ucgaggucga ggagcccucc      360

gacggcacca uccucggccg cuggugcggc uccggcaccg uccccggcaa gcagaucucc      420

aagggcaacc agauccgcau ccgcuucguc uccgacgagu acuuccccuc cgagcccggc      480

uucugcaucc acuacaacau cgucaugccc caguucaccg aggccgucuc ccccuccguc      540

cucccccccu ccgcccuccc ccucgaccuc cucaacaacg ccaucaccgc cuucuccacc      600

cucgaggacc ucauccgcua ccucgagccc gagcgcuggc agcucgaccu cgaggaccuc      660

uaccgcccca ccuggcagcu ccucggcaag gccuucgucu ucggccgcaa gucccgcguc      720

gucgaccuca accuccucac cgaggagguc cgccucuacu ccugcacccc ccgcaacuuc      780

uccgucucca uccgcgagga gcucaagcgc accgacacca ucuucuggcc cggcugccuc      840

cucgucaagc gcugcggcgg caacugcgcc ugcugccucc acaacugcaa cgagugccag      900

ugcguccccu ccaaggucac caagaaguac cacgaggucc uccagcuccg ccccaagacc      960

ggcguccgcg gccuccacaa gucccucacc gacgucgccc ucgagcacca cgaggagugc     1020

gacugcgucu gccgcggcuc caccggcggc ugaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  1653
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt2)

<400>  1653
gggagaaagc uuaccaugca ccgccucauc uucgucuaca cccucaucug cgccaacuuc       60

ugcuccugcc gcgacaccuc cgccaccccc caguccgccu ccaucaaggc ccuccgcaac      120

gccaaccucc gccgcgacga ccucuaccgc cgcgacgaga ccauccaggu caagggcaac      180

ggcuacgucc aguccccccg cuuccccaac uccuaccccc gcaaccuccu ccucaccugg      240

cgccuccacu cccaggagaa cacccgcauc cagcucgucu ucgacaacca guucggccuc      300

gaggaggccg agaacgacau cugccgcuac gacuucgucg aggucgagga caucuccgag      360

accuccacca ucauccgcgg ccgcuggugc ggccacaagg aggucccccc ccgcaucaag      420

ucccgcacca accagaucaa gaucaccuuc aaguccgacg acuacuucgu cgccaagccc      480

ggcuucaaga ucuacuacuc ccuccucgag gacuuccagc ccgccgccgc cuccgagacc      540

aacugggagu ccgucaccuc cuccaucucc ggcgucuccu acaacucccc cuccgucacc      600

gaccccaccc ucaucgccga cgcccucgac aagaagaucg ccgaguucga caccgucgag      660

gaccuccuca aguacuucaa ccccgagucc uggcaggagg accucgagaa cauguaccuc      720

gacacccccc gcuaccgcgg ccgcuccuac cacgaccgca aguccaaggu cgaccucgac      780

cgccucaacg acgacgccaa gcgcuacucc ugcacccccc gcaacuacuc cgucaacauc      840

cgcgaggagc ucaagcucgc caacgucguc uucuuccccc gcugccuccu cguccagcgc      900

ugcggcggca acugcggcug cggcaccguc aacuggcgcu ccugcaccug caacuccggc      960

aagaccguca agaaguacca cgagguccuc caguucgagc ccggccacau caagcgccgc     1020

ggccgcgcca agaccauggc ccucgucgac auccagcucg accaccacga gcgcugcgac     1080

ugcaucugcu ccucccgccc cccccgcuga ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  1654
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt2)

<400>  1654
gggagaaagc uuaccauggu cacccacucc aaguuccccg ccgccggcau gucccgcccc       60

cucgacaccu cccuccgccu caagaccuuc uccuccaagu ccgaguacca gcucgucguc      120

aacgccgucc gcaagcucca ggaguccggc uucuacuggu ccgccgucac cggcggcgag      180

gccaaccucc uccucuccgc cgagcccgcc ggcaccuucc ucauccgcga cuccuccgac      240

cagcgccacu ucuucacccu cuccgucaag acccaguccg gcaccaagaa ccuccgcauc      300

cagugcgagg gcggcuccuu cucccuccag uccgaccccc gcuccaccca gcccgucccc      360

cgcuucgacu gcguccucaa gcucguccac cacuacaugc ccccccccgg cgcccccucc      420

uuccccuccc cccccaccga gcccuccucc gagguccccg agcagcccuc cgcccagccc      480

cuccccggcu cccccccccg ccgcgccuac uacaucuacu ccggcggcga gaagaucccc      540

cucguccucu cccgcccccu cuccuccaac gucgccaccc uccagcaccu cugccgcaag      600

accgucaacg gccaccucga cuccuacgag aaggucaccc agcuccccgg ccccauccgc      660

gaguuccucg accaguacga cgccccccuc ugaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  1655
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt2)

<400>  1655
gggagaaagc uuaccauggu ccccuccgcc ggccagcucg cccucuucgc ccucggcauc       60

guccucgccg ccugccaggc ccucgagaac uccaccuccc cccucuccgc cgaccccccc      120

gucgccgccg ccgucgucuc ccacuucaac gacugccccg acucccacac ccaguucugc      180

uuccacggca ccugccgcuu ccucguccag gaggacaagc ccgccugcgu cugccacucc      240

ggcuacgucg gcgcccgcug cgagcacgcc gaccuccucg ccgucgucgc cgccucccag      300

aagaagcagg ccaucaccgc ccucgucguc gucuccaucg ucgcccucgc cguccucauc      360

aucaccugcg uccucaucca cugcugccag guccgcaagc acugcgagug gugccgcgcc      420

cucaucugcc gccacgagaa gcccuccgcc cuccucaagg gccgcaccgc cugcugccac      480

uccgagaccg ucgucugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  1656
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt2)

<400>  1656
gggagaaagc uuaccaugcc ccccuccggc cuccgccucc ucccccuccu ccucccccuc       60

cucuggcucc ucguccucac ccccggccgc cccgccgccg gccucuccac cugcaagacc      120

aucgacaugg agcucgucaa gcgcaagcgc aucgaggcca uccgcggcca gauccucucc      180

aagcuccgcc ucgccucccc ccccucccag ggcgaggucc cccccggccc ccuccccgag      240

gccguccucg cccucuacaa cuccacccgc gaccgcgucg ccggcgaguc cgccgagccc      300

gagcccgagc ccgaggccga cuacuacgcc aaggagguca cccgcguccu cauggucgag      360

acccacaacg agaucuacga caaguucaag caguccaccc acuccaucua cauguucuuc      420

aacaccuccg agcuccgcga ggccgucccc gagcccgucc uccucucccg cgccgagcuc      480

cgccuccucc gccucaagcu caaggucgag cagcacgucg agcucuacca gaaguacucc      540

aacaacuccu ggcgcuaccu cuccaaccgc cuccucgccc ccuccgacuc ccccgagugg      600

cucuccuucg acgucaccgg cgucguccgc caguggcucu cccgcggcgg cgagaucgag      660

ggcuuccgcc ucuccgccca cugcuccugc gacucccgcg acaacacccu ccaggucgac      720

aucaacggcu ucaccaccgg ccgccgcggc gaccucgcca ccauccacgg caugaaccgc      780

cccuuccucc uccucauggc caccccccuc gagcgcgccc agcaccucca guccucccgc      840

caccgccgcg cccucgacac caacuacugc uucuccucca ccgagaagaa cugcugcguc      900

cgccagcucu acaucgacuu ccgcaaggac cucggcugga aguggaucca cgagcccaag      960

ggcuaccacg ccaacuucug ccucggcccc ugccccuaca ucuggucccu cgacacccag     1020

uacuccaagg uccucgcccu cuacaaccag cacaaccccg gcgccuccgc cgcccccugc     1080

ugcguccccc aggcccucga gccccucccc aucgucuacu acgucggccg caagcccaag     1140

gucgagcagc ucuccaacau gaucguccgc uccugcaagu gcuccugagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  1657
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt2)

<400>  1657
gggagaaagc uuaccaugca cuacugcguc cucuccgccu uccucauccu ccaccucguc       60

accgucgccc ucucccucuc caccugcucc acccucgaca uggaccaguu caugcgcaag      120

cgcaucgagg ccauccgcgg ccagauccuc uccaagcuca agcucaccuc cccccccgag      180

gacuaccccg agcccgagga gguccccccc gaggucaucu ccaucuacaa cuccacccgc      240

gaccuccucc aggagaaggc cucccgccgc gccgccgccu gcgagcgcga gcgcuccgac      300

gaggaguacu acgccaagga ggucuacaag aucgacaugc cccccuucuu ccccuccgag      360

aacgccaucc cccccaccuu cuaccgcccc uacuuccgca ucguccgcuu cgacgucucc      420

gccauggaga agaacgccuc caaccucguc aaggccgagu uccgcgucuu ccgccuccag      480

aaccccaagg cccgcguccc cgagcagcgc aucgagcucu accagauccu caaguccaag      540

gaccucaccu cccccaccca gcgcuacauc gacuccaagg ucgucaagac ccgcgccgag      600

ggcgaguggc ucuccuucga cgucaccgac gccguccacg aguggcucca ccacaaggac      660

cgcaaccucg gcuucaagau cucccuccac ugccccugcu gcaccuucgu ccccuccaac      720

aacuacauca uccccaacaa guccgaggag cucgaggccc gcuucgccgg caucgacggc      780

accuccaccu acaccuccgg cgaccagaag accaucaagu ccacccgcaa gaagaacucc      840

ggcaagaccc cccaccuccu ccucaugcuc cuccccuccu accgccucga gucccagcag      900

accaaccgcc gcaagaagcg cgcccucgac gccgccuacu gcuuccgcaa cguccaggac      960

aacugcugcc uccgcccccu cuacaucgac uucaagcgcg accucggcug gaaguggauc     1020

cacgagccca agggcuacaa cgccaacuuc ugcgccggcg ccugccccua ccucuggucc     1080

uccgacaccc agcacucccg cguccucucc cucuacaaca ccaucaaccc cgaggccucc     1140

gccucccccu gcugcgucuc ccaggaccuc gagccccuca ccauccucua cuacaucggc     1200

aagaccccca agaucgagca gcucuccaac augaucguca aguccugcaa gugcuccuga     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  1658
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt2)

<400>  1658
gggagaaagc uuaccaugaa gaugcaccuc cagcgcgccc ucgucguccu cgcccuccuc       60

aacuucgcca ccgucucccu cucccucucc accugcacca cccucgacuu cggccacauc      120

aagaagaagc gcgucgaggc cauccgcggc cagauccucu ccaagcuccg ccucaccucc      180

ccccccgagc ccaccgucau gacccacguc cccuaccagg uccucgcccu cuacaacucc      240

acccgcgagc uccucgagga gaugcacggc gagcgcgagg agggcugcac ccaggagaac      300

accgaguccg aguacuacgc caaggagauc cacaaguucg acaugaucca gggccucgcc      360

gagcacaacg agcucgccgu cugccccaag ggcaucaccu ccaaggucuu ccgcuucaac      420

gucuccuccg ucgagaagaa ccgcaccaac cucuuccgcg ccgaguuccg cguccuccgc      480

guccccaacc ccuccuccaa gcgcaacgag cagcgcaucg agcucuucca gauccuccgc      540

cccgacgagc acaucgccaa gcagcgcuac aucggcggca agaaccuccc cacccgcggc      600

accgccgagu ggcucuccuu cgacgucacc gacaccgucc gcgaguggcu ccuccgccgc      660

gaguccaacc ucggccucga gaucuccauc cacugccccu gccacaccuu ccagcccaac      720

ggcgacaucc ucgagaacau ccacgagguc auggagauca aguucaaggg cgucgacaac      780

gaggacgacc acggccgcgg cgaccucggc cgccucaaga agcagaagga ccaccacaac      840

ccccaccuca uccucaugau gauccccccc caccgccucg acaaccccgg ccagggcggc      900

cagcgcaaga agcgcgcccu cgacaccaac uacugcuucc gcaaccucga ggagaacugc      960

ugcguccgcc cccucuacau cgacuuccgc caggaccucg gcuggaagug gguccacgag     1020

cccaagggcu acuacgccaa cuucugcucc ggccccugcc ccuaccuccg cuccgccgac     1080

accacccacu ccaccguccu cggccucuac aacacccuca accccgaggc cuccgccucc     1140

cccugcugcg ucccccagga ccucgagccc cucaccaucc ucuacuacgu cggccgcacc     1200

cccaaggucg agcagcucuc caacaugguc gucaaguccu gcaagugcuc cugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  1659
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt2)

<400>  1659
gggagaaagc uuaccauggc ccccgucgcc gucugggccg cccucgccgu cggccucgag       60

cucugggccg ccgcccacgc ccuccccgcc caggucgccu ucacccccua cgcccccgag      120

cccggcucca ccugccgccu ccgcgaguac uacgaccaga ccgcccagau gugcugcucc      180

aagugcuccc ccggccagca cgccaagguc uucugcacca agaccuccga caccgucugc      240

gacuccugcg aggacuccac cuacacccag cucuggaacu ggguccccga gugccucucc      300

ugcggcuccc gcugcuccuc cgaccagguc gagacccagg ccugcacccg cgagcagaac      360

cgcaucugca ccugccgccc cggcugguac ugcgcccucu ccaagcagga gggcugccgc      420

cucugcgccc cccuccgcaa gugccgcccc ggcuucggcg ucgcccgccc cggcaccgag      480

accuccgacg ucgucugcaa gcccugcgcc cccggcaccu ucuccaacac caccuccucc      540

accgacaucu gccgccccca ccagaucugc aacgucgucg ccauccccgg caacgccucc      600

auggacgccg ucugcaccuc caccuccccc acccgcucca uggcccccgg cgccguccac      660

cucccccagc ccgucuccac ccgcucccag cacacccagc ccacccccga gcccuccacc      720

gcccccucca ccuccuuccu ccuccccaug ggccccuccc cccccgccga gggcuccacc      780

ggcgacuucg cccuccccgu cggccucauc gucggcguca ccgcccucgg ccuccucauc      840

aucggcgucg ucaacugcgu caucaugacc caggucaaga agaagccccu cugccuccag      900

cgcgaggcca agguccccca ccuccccgcc gacaaggccc gcggcaccca gggccccgag      960

cagcagcacc uccucaucac cgcccccucc uccuccuccu ccucccucga guccuccgcc     1020

uccgcccucg accgccgcgc ccccacccgc aaccagcccc aggcccccgg cgucgaggcc     1080

uccggcgccg gcgaggcccg cgccuccacc ggcuccuccg acuccucccc cggcggccac     1140

ggcacccagg ucaacgucac cugcaucguc aacgucugcu ccuccuccga ccacuccucc     1200

cagugcuccu cccaggccuc cuccaccaug ggcgacaccg acuccucccc cuccgagucc     1260

cccaaggacg agcagguccc cuucuccaag gaggagugcg ccuuccgcuc ccagcucgag     1320

acccccgaga cccuccucgg cuccaccgag gagaagcccc ucccccucgg cguccccgac     1380

gccggcauga agcccuccug aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  1660
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt2)

<400>  1660
gggagaaagc uuaccaugcc cgucaugcgc cucuuccccu gcuuccucca gcuccucgcc       60

ggccucgccc uccccgccgu ccccccccag cagugggccc ucuccgccgg caacggcucc      120

uccgaggucg aggucguccc cuuccaggag gucuggggcc gcuccuacug ccgcgcccuc      180

gagcgccucg ucgacgucgu cuccgaguac cccuccgagg ucgagcacau guucuccccc      240

uccugcgucu cccuccuccg cugcaccggc ugcugcggcg acgagaaccu ccacugcguc      300

cccgucgaga ccgccaacgu caccaugcag cuccucaaga uccgcuccgg cgaccgcccc      360

uccuacgucg agcucaccuu cucccagcac guccgcugcg agugccgccc ccuccgcgag      420

aagaugaagc ccgagcgccg ccgccccaag ggccgcggca agcgccgccg cgagaagcag      480

cgccccaccg acugccaccu cugcggcgac gccguccccc gccgcugagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  1661
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt2)

<400>  1661
gggagaaagc uuaccaugac cgaccgccag accgacaccg cccccucccc cuccuaccac       60

cuccuccccg gccgccgccg caccgucgac gccgccgccu cccgcggcca gggccccgag      120

cccgcccccg gcggcggcgu cgagggcguc ggcgcccgcg gcgucgcccu caagcucuuc      180

guccagcucc ucggcugcuc ccgcuucggc ggcgccgucg uccgcgccgg cgaggccgag      240

cccuccggcg ccgcccgcuc cgccuccucc ggccgcgagg agccccagcc cgaggagggc      300

gaggaggagg aggagaagga ggaggagcgc ggcccccagu ggcgccucgg cgcccgcaag      360

cccggcuccu ggaccggcga ggccgccguc ugcgccgacu ccgcccccgc cgcccgcgcc      420

ccccaggccc ucgcccgcgc cuccggccgc ggcggccgcg ucgcccgccg cggcgccgag      480

gaguccggcc ccccccacuc ccccucccgc cgcggcuccg ccucccgcgc cggccccggc      540

cgcgccuccg agaccaugaa cuuccuccuc uccugggucc acuggucccu cgcccuccuc      600

cucuaccucc accacgccaa guggucccag gccgccccca uggccgaggg cggcggccag      660

aaccaccacg aggucgucaa guucauggac gucuaccagc gcuccuacug ccaccccauc      720

gagacccucg ucgacaucuu ccaggaguac cccgacgaga ucgaguacau cuucaagccc      780

uccugcgucc cccucaugcg cugcggcggc ugcugcaacg acgagggccu cgagugcguc      840

cccaccgagg aguccaacau caccaugcag aucaugcgca ucaagcccca ccagggccag      900

cacaucggcg agauguccuu ccuccagcac aacaagugcg agugccgccc caagaaggac      960

cgcgcccgcc aggagaagaa guccguccgc ggcaagggca agggccagaa gcgcaagcgc     1020

aagaaguccc gcuacaaguc cugguccguc uacgucggcg cccgcugcug ccucaugccc     1080

uggucccucc ccggccccca ccccugcggc cccugcuccg agcgccgcaa gcaccucuuc     1140

guccaggacc cccagaccug caagugcucc ugcaagaaca ccgacucccg cugcaaggcc     1200

cgccagcucg agcucaacga gcgcaccugc cgcugcgaca agccccgccg cugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  1662
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt2)

<400>  1662
gggagaaagc uuaccaugaa cuuccuccuc uccugggucc acuggucccu cgcccuccuc       60

cucuaccucc accacgccaa guggucccag gccgccccca uggccgaggg cggcggccag      120

aaccaccacg aggucgucaa guucauggac gucuaccagc gcuccuacug ccaccccauc      180

gagacccucg ucgacaucuu ccaggaguac cccgacgaga ucgaguacau cuucaagccc      240

uccugcgucc cccucaugcg cugcggcggc ugcugcaacg acgagggccu cgagugcguc      300

cccaccgagg aguccaacau caccaugcag aucaugcgca ucaagcccca ccagggccag      360

cacaucggcg agauguccuu ccuccagcac aacaagugcg agugccgccc caagaaggac      420

cgcgcccgcc aggagaagaa guccguccgc ggcaagggca agggccagaa gcgcaagcgc      480

aagaaguccc gcuacaaguc cugguccguc uacgucggcg cccgcugcug ccucaugccc      540

uggucccucc ccggccccca ccccugcggc cccugcuccg agcgccgcaa gcaccucuuc      600

guccaggacc cccagaccug caagugcucc ugcaagaaca ccgacucccg cugcaaggcc      660

cgccagcucg agcucaacga gcgcaccugc cgcugcgaca agccccgccg cugaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  1663
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt2)

<400>  1663
gggagaaagc uuaccauguc cccccuccuc cgccgccucc uccucgccgc ccuccuccag       60

cucgcccccg cccaggcccc cgucucccag cccgacgccc ccggccacca gcgcaagguc      120

gucuccugga ucgacgucua cacccgcgcc accugccagc cccgcgaggu cgucgucccc      180

cucaccgucg agcucauggg caccgucgcc aagcagcucg uccccuccug cgucaccguc      240

cagcgcugcg gcggcugcug ccccgacgac ggccucgagu gcguccccac cggccagcac      300

cagguccgca ugcagauccu caugauccgc uaccccuccu cccagcucgg cgagaugucc      360

cucgaggagc acucccagug cgagugccgc cccaagaaga aggacuccgc cgucaagccc      420

gaccgcgccg ccacccccca ccaccgcccc cagccccgcu ccguccccgg cugggacucc      480

gcccccggcg cccccucccc cgccgacauc acccacccca cccccgcccc cggccccucc      540

gcccacgccg cccccuccac caccuccgcc cucacccccg gccccgccgc cgccgccgcc      600

gacgccgccg ccuccuccgu cgccaagggc ggcgccugag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  1664
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt2)

<400>  1664
gggagaaagc uuaccaugca ccuccucggc uucuucuccg ucgccugcuc ccuccucgcc       60

gccgcccucc uccccggccc ccgcgaggcc cccgccgccg ccgccgccuu cgaguccggc      120

cucgaccucu ccgacgccga gcccgacgcc ggcgaggcca ccgccuacgc cuccaaggac      180

cucgaggagc agcuccgcuc cgucuccucc gucgacgagc ucaugaccgu ccucuacccc      240

gaguacugga agauguacaa gugccagcuc cgcaagggcg gcuggcagca caaccgcgag      300

caggccaacc ucaacucccg caccgaggag accaucaagu ucgccgccgc ccacuacaac      360

accgagaucc ucaaguccau cgacaacgag uggcgcaaga cccagugcau gccccgcgag      420

gucugcaucg acgucggcaa ggaguucggc gucgccacca acaccuucuu caagcccccc      480

ugcgucuccg ucuaccgcug cggcggcugc ugcaacuccg agggccucca gugcaugaac      540

accuccaccu ccuaccucuc caagacccuc uucgagauca ccgucccccu cucccagggc      600

cccaagcccg ucaccaucuc cuucgccaac cacaccuccu gccgcugcau guccaagcuc      660

gacgucuacc gccaggucca cuccaucauc cgccgcuccc uccccgccac ccucccccag      720

ugccaggccg ccaacaagac cugccccacc aacuacaugu ggaacaacca caucugccgc      780

ugccucgccc aggaggacuu cauguucucc uccgacgccg gcgacgacuc caccgacggc      840

uuccacgaca ucugcggccc caacaaggag cucgacgagg agaccugcca gugcgucugc      900

cgcgccggcc uccgccccgc cuccugcggc ccccacaagg agcucgaccg caacuccugc      960

cagugcgucu gcaagaacaa gcucuucccc ucccagugcg gcgccaaccg cgaguucgac     1020

gagaacaccu gccagugcgu cugcaagcgc accugccccc gcaaccagcc ccucaacccc     1080

ggcaagugcg ccugcgagug caccgagucc ccccagaagu gccuccucaa gggcaagaag     1140

uuccaccacc agaccugcuc cugcuaccgc cgccccugca ccaaccgcca gaaggccugc     1200

gagcccggcu ucuccuacuc cgaggagguc ugccgcugcg uccccuccua cuggaagcgc     1260

ccccagaugu ccugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  1665
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt2)

<400>  1665
gggagaaagc uuaccaugua ccgcgagugg gucgucguca acgucuucau gaugcucuac       60

guccagcucg uccagggcuc cuccaacgag cacggccccg ucaagcgcuc cucccagucc      120

acccucgagc gcuccgagca gcagauccgc gccgccuccu cccucgagga gcuccuccgc      180

aucacccacu ccgaggacug gaagcucugg cgcugccgcc uccgccucaa guccuucacc      240

uccauggacu cccgcuccgc cucccaccgc uccacccgcu ucgccgccac cuucuacgac      300

aucgagaccc ucaaggucau cgacgaggag uggcagcgca cccagugcuc cccccgcgag      360

accugcgucg aggucgccuc cgagcucggc aaguccacca acaccuucuu caagcccccc      420

ugcgucaacg ucuuccgcug cggcggcugc ugcaacgagg agucccucau cugcaugaac      480

accuccaccu ccuacaucuc caagcagcuc uucgagaucu ccgucccccu caccuccguc      540

cccgagcucg uccccgucaa ggucgccaac cacaccggcu gcaagugccu ccccaccgcc      600

ccccgccacc ccuacuccau cauccgccgc uccauccaga uccccgagga ggaccgcugc      660

ucccacucca agaagcucug ccccaucgac augcucuggg acuccaacaa gugcaagugc      720

guccuccagg aggagaaccc ccucgccggc accgaggacc acucccaccu ccaggagccc      780

gcccucugcg gcccccacau gauguucgac gaggaccgcu gcgagugcgu cugcaagacc      840

cccugcccca aggaccucau ccagcacccc aagaacugcu ccugcuucga gugcaaggag      900

ucccucgaga ccugcugcca gaagcacaag cucuuccacc ccgacaccug cuccugcgag      960

gaccgcugcc ccuuccacac ccgccccugc gccuccggca agaccgccug cgccaagcac     1020

ugccgcuucc ccaaggagaa gcgcgccgcc cagggccccc acucccgcaa gaaccccuga     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  1666
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt3)

<400>  1666
gggagaaagc uuaccaugga cagcgaugag accggcuucg aacacuccgg gcugugggug       60

ucuguccucg ccggacuucu guugggugcu ugccaggcac aucccauccc ugacucaagu      120

ccauuacugc aauuuggcgg gcagguuaga cagagguacc uauauacaga ugacgcccag      180

caaacugagg cgcaccucga aauucgggag gauggaacgg ugggcggugc ugccgaccag      240

agcccggaau cccugcuuca gcugaaggca uugaaacccg ggguaauaca gauccucgga      300

gugaagaccu cucgcuuccu gugucaacga ccugauggcg cccuguacgg cucgcuccau      360

uuugacccag aggcuugcuc auuccgugag uuacugcuug aagaugggua uaacgucuac      420

cagagcgagg cacacggauu gccccugcau cuaccuggua auaaaagucc acacagagac      480

cccgccccua ggggcccagc ucgguuucuc ccgcugcccg ggcuuccucc agcccugccc      540

gaaccuccag gaauuuuggc gccccagccg ccugaugugg gcuccucuga cccccucagc      600

augguugguc caucccaggg gcgcucaccu aguuaugcaa gcugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  1667
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt3)

<400>  1667
gggagaaagc uuaccaugca cagcuuuccc ccucugcucc uucuguuguu cuggggcgug       60

gucucccauu cuuucccagc caccuuagag acacaggaac aagacguuga ucuggugcag      120

aaguaccuag agaaauauua caaccucaag aaugacggga gacagguaga gaaaaggcgg      180

aacucaggac cgguggucga aaagcugaaa cagaugcaag aauuuuucgg ucuuaaggug      240

acuggcaagc ccgaugcuga gacgcugaaa guuaugaagc agccucgcug cggggugcca      300

gacgucgcac aguuuguguu gaccgaggga aauccccgau gggaacagac acaccucacu      360

uaucguaucg agaacuacac cccugaucug ccaagagccg acguagauca ugcgauugaa      420

aaggcuuucc aacuguggag uaauguuaca ccccucaccu uuacuaaagu gagcgagggc      480

caggccgaca uaaugaucuc cuucgucagg ggugaucacc gggacaacuc uccuuuugau      540

gggccaggag gcaauuuagc acaugccuuc cagccgggcc ccgggauugg aggugacgcu      600

cacuuugaug aggacgaacg cuggacaaac aauuucagag aguauaaccu gcacagggug      660

gcagcccaug aacuuggcca cucguugggg cugucacaua gcaccgacau cggagcucua      720

auguacccua guuauacguu uuccggcgau gugcagcucg cccaagacga uauugacggu      780

auccaggcga uauacgggcg gucucagaau ccaguccaac ccaucggacc ucagacucca      840

aaagcaugug auagcaagcu gaccuucgac gccauuacaa cuauccgcgg cgagguuaug      900

uucuuuaagg aucgauucua caugagaacc aaccccuuuu auccggaagu ggagcuuaau      960

uucauuuccg uauuuuggcc ucagcugccc aacggcuugg aggcugccua cgaguucgca     1020

gacagggaug aagugcgguu uuucaaaggg aauaaguauu gggcugucca gggacaaaac     1080

gugcuccacg guuacccaaa agacaucuau ucaaguuuug gcuucccucg uacaguuaag     1140

cacauagaug ccgcgcugag cgaagagaac accgggaaaa cguacuuuuu cguggccaau     1200

aaguauuggc gcuacgacga auacaaaaga ucuauggacc ccggauaucc aaagaugauu     1260

gcacaugauu uucccggcau cggucacaag gucgacgcug uguucaugaa agauggguuc     1320

uuuuacuucu uucauggcac uaggcaguau aaguucgacc cuaaaacaaa gcggauuuua     1380

acccugcaga aagccaacuc cugguuuaau ugccgaaaga acugaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  1668
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt3)

<400>  1668
gggagaaagc uuaccaugca cagcuuuccc ccucugcucc uucuguuguu cuggggcgug       60

gucucccauu cuuucguuuu aaccgagggg aacccaagau gggaacagac acaccugacu      120

uacaggaucg agaauuauac gccggaccua ccccgggccg auguggacca ugcuauugaa      180

aaggcauuuc aacucugguc aaacguaacc ccucugacau ucacuaaagu gagugaggga      240

caggccgaua uaaugaucag cuuuguccgc ggugaccacc gagauaauuc cccauucgac      300

ggccccgggg gaaaccuugc gcaugcuuuu cagccuggcc cagguauugg gggagaugcc      360

cacuucgacg aagaugagcg uuggaccaau aacuuuagag aguacaaucu gcacagggug      420

gcagcccaug aauugggcca cucucucggc cugucgcauu caacagacau cggggcucug      480

auguauccca gcuacaccuu caguggagau guucagcucg cacaagacga uauugacggu      540

auccaggcca uauauggccg gucccagaac ccugugcagc caaucgggcc gcaaacuccc      600

aaggcuugcg acucuaaauu aacauuugau gccauuacca cgauccgcgg agaggucaug      660

uucuuuaagg acagauucua caugaggacu aauccuuucu auccagaagu ggagcugaac      720

uuuauuagcg uauucuggcc ccagcuuccu aauggcuugg aggcggcaua cgaauuugcc      780

gaucgggacg agguucgcuu cuuuaaaggu aacaaguacu gggcugugca ggggcagaau      840

guccugcacg gauauccaaa ggauaucuac uccucauucg gcuuuccccg aaccgugaaa      900

cacauagacg ccgcacuaag ugaagagaac acaggcaaga cuuauuucuu uguggcuaau      960

aaauacugga gauaugauga auacaagagg agcauggacc cgggguaucc uaaaaugauu     1020

gcccaugauu uccccggaau cggucacaag gucgacgcgg uuuuuaugaa ggauggcuuc     1080

uuuuacuucu uccaugggac ccggcaauac aaauuugacc caaagacaaa acguauucuc     1140

acccugcaga aggccaacuc uugguucaac ugucgcaaaa auugaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  1669
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt3)

<400>  1669
gggagaaagc uuaccaugaa gaaaaacauc cugaagauuc ucauggacag cuacuccaaa       60

gagucuaaga uacagaccgu gagaaggguc acaucaguua gucuucuggc cguguauuug      120

acuaugaaua cgagcuccuu aguacuggcu aaacccaucg aaaacaccaa ugauacaucu      180

auuaagaacg uggagaagcu acggaaugca ccuaacgaag aaaauucgaa aaaggucgaa      240

gacucaaaga acgauaaggu ggagcacguu aaaaauaucg aggaagccaa gguggagcaa      300

gucgcgccag aaguaaagag caaaaguacu cuccgcuccg cuucuauugc caacaccaau      360

agcgagaagu acgacuucga guaucugaac ggccuuuccu acacagaacu gaccaauuug      420

aucaaaaaca uaaaguggaa ucagaucaac gggcucuuua acuauucaac uggaagucag      480

aaauucuuug gugauaagaa ucgagugcag gcaauuauca acgcccugca agagagcggc      540

cguacauaca ccgcuaauga caugaaaggg auugaaacgu ucacugaggu ucugagagca      600

ggauuuuauc ucggcuacua caacgauggu uuaucuuauc ugaaugacag gaacuuccag      660

gauaagugca ucccggccau gauagcuauu cagaagaauc ccaacuuuaa acuugggacc      720

gccgugcagg acgaagucau cacauccuug ggaaagcuga uuggcaaugc gucagcaaac      780

gccgaggugg ugaauaacug ugucccuguu cuaaaacaau uccgggagaa ucucaaccag      840

uacgcuccag auuaugugaa gggcacugcc guaaaugaac ugaucaaagg gaucgaguuu      900

gacuucagcg gagcagcuua cgaaaaggau gugaagacca ugcccuggua ugguaaaauu      960

gacccuuuua uaaacgagcu uaaggcccug ggcuuguacg ggaacaucac aagugcgacc     1020

gaaugggccu cugacgucgg aauuuauuac cucuccaaau ucggccugua cagcacgaau     1080

cgcaacgaua ucgugcaguc guuagagaag gcaguugaca uguauaaaua cgguaagaua     1140

gcuuuugugg ccauggagag aauuacuugg gauuaugacg ggaucggauc uaauggcaag     1200

aaagucgauc augacaaguu ccuggaugac gcugaaaaac acuaccuccc aaagacauau     1260

accuucgaua acggcacuuu uaucauuagg gccggggaca aaguguccga ggaaaagauc     1320

aagcggcuuu acugggcauc acgcgaggua aaaagucagu uccaucgagu ugugggaaau     1380

gauaaggccc uggaagucgg uaacgcugac gacguguuga caaugaaaau uuuuaauagc     1440

cccgaggagu auaaguucaa caccaauaua aacggcgucu ccacggauaa ugggggacua     1500

uacaucgaac cuagaggcac cuuuuacaca uaugagagga cuccacaaca gucuauuuuc     1560

agccuggagg agcucuuucg gcacgaguac acccauuauc ugcaggcgcg uuaccuugug     1620

gacggucugu gggggcaagg cccguucuau gaaaagaacc gcuugacaug guuugaugag     1680

ggaacugcag aguucuuugc cggcucaacc agaacaagug ggguucuccc caggaagucc     1740

auccugggau acuuagcuaa agacaaggug gaucaccggu auagccugaa gaaaacccua     1800

aauucugguu acgacgauuc agacuggaug uucuacaacu auggcuuugc cguagcacac     1860

uaccucuaug aaaaggauau gccuacuuuc aucaaaauga auaaggccau ucugaacacg     1920

gacgucaaaa guuacgauga aauaaucaag aaacuuagcg acgaugcuaa caaaaauaca     1980

gaguaucaga accauauuca ggaguuggcc gacaaguacc agggggcagg aaucccacug     2040

guguccgacg auuaucucaa agaccacggc uacaagaaag cgucugaagu uuacucggag     2100

auuagcaagg cugccucccu gaccaauacu ucagugaccg cagaaaagag ucaauauuuc     2160

aacacauuua cccuucgagg uacuuacaca ggggagacgu cuaaaggcga guucaaggau     2220

ugggacgaaa ugagcaaaaa gcuggaugga accuuggagu cccucgccaa aaauucaugg     2280

agcggcuaua agacucugac agcuuacuuu accaacuauc gcgucacauc ugacaauaag     2340

gugcaguacg auguaguguu ccaugggguu uuaacugaca acgccgauau cuccaauaac     2400

aaagcaccca uagcuaaggu caccggaccu aguacgggug ccgugggcag aaauaucgaa     2460

uuuagcggga aagacucuaa ggaugaggac ggaaaaauug uguccuauga uugggacuuc     2520

ggcgacggug cgaccucaag ggggaagaac aguguccacg ccuacaaaaa ggcuggcaca     2580

uacaauguua cucugaaggu gaccgaugac aaaggagcaa cagccacuga gagcuuuacc     2640

aucgaaauua agaacgaaga uacgacaacc ccaaucacua aagagaugga gcccaaugac     2700

gauauaaagg aagcuaacgg cccgauugug gaggggguaa cagucaaagg agaccuaaac     2760

ggcucggaug acgccgauac cuucuauuuu gacgugaagg aagaugguga cguuacuauc     2820

gagcucccuu acuccggguc uagcaauuuc accuggcugg uguauaagga gggagacgau     2880

cagaaccaca uugcaucagg caucgacaaa aauaacagua aggucgguac auuuaaaucc     2940

acgaagggcc ggcauuacgu guucauauau aaacacgauu cugcgagcaa uaucuccuac     3000

ucacuuaaca uuaagggguu gggaaaugaa aagcugaaag agaaggaaaa caaugacagc     3060

agugauaaag ccaccguuau ccccaacuuu aauacuacaa ugcagggcuc ucuccugggg     3120

gacgauuccc gcgacuauua cagcuucgag gugaaggaag agggagaggu aaacauugaa     3180

uuagauaaaa aggacgaguu cggcgucacc uggacacugc auccagaauc gaauaucaac     3240

gauagaauaa cuuacgguca aguggacggg aauaaggugu caaacaaagu caaacuuagg     3300

ccuggaaaau auuacuugcu cguuuauaag uacucuggca gugguaauua ugagcugcgu     3360

gugaacaaau gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  1670
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt3)

<400>  1670
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuucu uuucuccucu       60

gccuacucaa uugcuaacac aaauagugag aaauaugacu uugaauaccu gaacggcuug      120

agcuauacug aguuaacgaa ucugauaaag aacaucaaau ggaaucagau uaacgggcua      180

uucaauuacu ccaccggauc ucaaaaguuu uucggugaua aaaacagagu ccaggcaauc      240

auuaaugccc uccaggaauc gggcaggaca uauacugcga acgacaugaa ggggaucgag      300

accuuuacag aaguucugcg ggcuggauuc uaccuuggcu auuacaauga uggucuguca      360

uacuugaacg accgcaauuu ucaggauaag ugcauacccg ccaugaucgc aauucagaaa      420

aacccuaauu ucaagcucgg gaccgccgug caagacgagg uaaucacuag ccugggaaaa      480

cugauuggca acgcuagugc aaacgccgag guggucaaua acugugugcc aguucucaag      540

caguuucgag aaaauuuaaa ccaguaugcu ccggauuacg ugaaaggcac agccgucaau      600

gagcugauca aggggauaga auuugacuuu uccggagcgg cauaugagaa ggaugugaaa      660

accaugcccu gguacgguaa gauugacccu uucaucaacg agcuuaaagc cuugggccug      720

uaugggaaua uuacgucugc uacugaaugg gccagcgaug uaggaaucua cuaucuaucc      780

aaguucggcc ucuacucaac caaccguaau gacaucguuc aaagucugga gaaagcagug      840

gauauguaca aguaugguaa aauugcuuuu gucgccaugg aaagaauaac augggacuac      900

gacgggaucg gaagcaacgg caagaaggug gaucacgaca aauuccuuga ugacgcggag      960

aagcauuauc ugccaaaaac uuacaccuuu gauaauggca cauucauuau cagggccggg     1020

gacaaggugu cugaagagaa aauaaagcgg uuguauuggg caucccgcga ggucaaguca     1080

caguuucaca gaguuguggg aaacgauaaa gcucucgaag uagguaaugc cgacgaugug     1140

cugaccauga agauuuucaa cagccccgag gaauacaaau uuaauacgaa caucaacggc     1200

gucaguacug acaauggggg auuauauauc gagccuaggg gcacauucua caccuacgaa     1260

cggacuccac agcagucuau uuucucccug gaggagcugu uccgccauga auauacacac     1320

uaccuucaag cucgauaucu gguggauggu uugugggggc agggccccuu uuacgagaag     1380

aacagacuaa ccugguucga cgaaggaacg gccgaguuuu ucgcaggcag caccaggaca     1440

ucggggguuc ugccucggaa aucuauccuc ggauaucugg ccaaggacaa gguggaucau     1500

cguuacuccc uuaaaaagac ucucaauuca gguuaugacg auagugacug gauguucuac     1560

aacuacggcu uugcugucgc gcacuauuug uacgaaaaag auaugccaac cuucauuaag     1620

augaauaaag caauacucaa cacagacgua aagagcuaug augagaucau uaagaaacug     1680

uccgacgaug ccaauaagaa cacugaguac cagaaucaca uccaagaauu agcugacaaa     1740

uaucaggggg ccggaauccc gcuggugucu gaugacuacc uaaaggauca uggcuauaaa     1800

aaggcaagcg agguuuacuc agaaauuagu aaagccgcuu cccucaccaa cacaagcgug     1860

accgccgaga agucucagua cuuuaauacu uucacgcugc gcgguacaua uaccggggag     1920

acuucaaagg gcgaauuuaa agacugggac gagaugagua agaaacuuga uggaaccuug     1980

gaaagccugg caaagaacuc cuggucuggc uacaaaacac ucaccgcgua uuucacuaau     2040

uacagaguca caucggacaa caaggugcag uaugaugucg uguuucacgg gguucugacg     2100

gacaaugcug auauaagcaa caacaaggcc cccaucgcaa aagugaccgg accuuccacu     2160

ggugccguag gcaggaauau ugaguucuca gggaaggaca guaaagauga agacggaaag     2220

aucgucucuu acgauuggga cuuuggcgau ggugcuacaa gccgggggaa aaacuccgug     2280

caugccuaua agaaggcagg caccuacaau guuacacuua aagugacuga cgauaaggga     2340

gcuaccgcca cggagucauu caccauugag aucaaaaacg aagacacaac uaccccaaua     2400

acaaaggaga uggaacccaa ugacgauauc aaagaggcga acggcccuau ugucgaaggg     2460

gugacuguaa agggagaccu gaauggcagc gaugacgccg auaccuuuua cuucgacgug     2520

aaggaggaug gugacguuac gaucgaguug ccauauucug gguccaguaa cuuuacaugg     2580

cucgucuaca aagaaggaga ugaccaaaau cacauugcua gcggcaucga uaagaacaau     2640

ucuaaagugg guaccuucaa guccacuaaa ggccgacacu auguguucau auacaagcau     2700

gacucagcaa guaacauuag cuauucgcug aauaucaaag gguuaggaaa cgagaagcug     2760

aaggaaaaag agaauaacga cuccucugau aaggccacag ucauucccaa cuuuaauacc     2820

acuaugcagg gcagccuacu cggggacgau ucacgcgacu acuauaguuu cgaaguuaaa     2880

gaggagggag aagugaacau cgagcuggau aagaaagacg aauuuggcgu gaccuggaca     2940

cuucacccgg aguccaauau aaacgauaga aucacguacg gucagguaga cgggaauaag     3000

gucucuaaca aggugaaauu gaggccugga aaguacuauc ugcucguuua caaauauagc     3060

ggcuccggua auuacgagcu gcgggugaac aagugaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  1671
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt3)

<400>  1671
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuucu uuucuccucu       60

gccuacucaa ugaaaaagaa cauucugaaa auauugaugg acaguuauag caaggagucc      120

aaaauccaga cagucagaag gguuacuucu gugucguuac uggcuguaua ccuaacgaug      180

aauaccucaa gccucgugcu ggcaaagccc auugaaaaca caaaugauac uagcaucaag      240

aacgucgaga aacuucggaa ugccccuaac gaagaaaauu ccaagaaagu ggaagacucu      300

aagaacgaua aaguugagca cgugaagaau auugaggaag cgaaggucga gcaaguggcu      360

ccagaaguaa aaagcaaguc cacccugcgc ucagccaguc gacguagaag gaaacggauc      420

gcaaacacaa auagcgagaa guaugacuuu gaguacuuga acggccucuc uuauaccgaa      480

cugacuaauc ugaucaaaaa cauaaagugg aaucagauua acggacucuu caacuacucc      540

acaggaucac agaaauuuuu cggugauaag aaucgcguuc aggccaucau uaacgcuuua      600

caagagagcg gcagaaccua uacggcaaau gacaugaagg ggaucgaaac uuuuaccgag      660

gugcugaggg ccggauucua ccuuggcuac uauaacgaug guuugaguua ccugaaugac      720

cggaacuuuc aggauaaaug cauaccggcu augauugcca uccagaagaa ucccaacuuc      780

aaacuaggga cagcggucca ggacgaagug auuacuucuc ucggaaagcu gaucggcaau      840

gcauccgcca acgcugaggu ggucaauaac uguguuccug ugcuuaaaca auuucgcgag      900

aaucugaacc aguaugcccc agauuacgua aagggcaccg cagugaauga auugaucaag      960

gggauugagu ucgacuuuag cggagcugcc uaugaaaaag augucaagac aaugcccugg     1020

uacgguaaaa uagacccuuu caucaacgag cucaaggcgc ugggcuuaua ugggaacauu     1080

accucggcca cggaaugggc aucugacgug ggaaucuacu accuguccaa auucggccuc     1140

uauucaacua aucgaaacga uauaguucag agucuugaga aggcugugga cauguacaag     1200

uaugguaaaa uugccuuugu cgcuauggag agaaucacau gggauuacga cgggaucgga     1260

agcaauggca agaaagugga ucaugacaag uuccuggaug acgccgaaaa acacuauuug     1320

ccaaagaccu acacuuuuga uaacggcaca uucauuauca gggcagggga caagguaucc     1380

gaggagaaaa uuaagcggcu auauugggcc ucucgugagg uuaaaagcca guuucaucgc     1440

guggucggaa augauaaggc ucuggaagug gguaacgcgg acgacguccu caccaugaaa     1500

auauucaauu cacccgagga guacaaguuu aacacgaaua ucaacggcgu gaguaccgau     1560

aaugggggac uguacauuga accuagaggc acauucuaua cuuacgagag gaccccacaa     1620

caguccaucu uuagccuuga ggaacuguuc cggcacgagu auacacauua cuugcaggca     1680

cgauaucucg uugacggucu gugggggcaa ggcccguuuu acgagaaaaa ccgcuuaacu     1740

ugguucgaug aaggaaccgc cgaauuuuuc gcuggcucua caagaaccuc aggggugcug     1800

cccaggaaga guauccuagg auaucucgcc aaggacaaag uagaucaccg guacagccug     1860

aagaaaacuc uuaauuccgg uuacgacgau ucugacugga uguucuauaa cuacggcuuu     1920

gcagucgccc acuauuugua cgagaaggau augccuacgu ucauuaaaau gaauaaggcu     1980

auacugaaca cagacgugaa gucguaugau gaaaucauua aaaagcucag cgacgaugcc     2040

aacaaaaaua ccgaguacca gaaccauauc caggagcugg cagacaagua ucagggggcg     2100

gggauuccac uuguuuccga cgauuaccug aaagaccacg gcuacaagaa ggcuucagaa     2160

guguauagug agaucucuaa agccgcaagu uugacuaaua ccuccgucac agccgaaaag     2220

ucacaauacu uuaacaccuu cacucuccgc gguacauaua cgggggagac cagcaaaggc     2280

gaauuuaagg auugggacga gaugucuaaa aagcuggaug gaacuuuaga gucccuggcu     2340

aagaauaguu ggagcggcua caaaacacua accgccuauu ucacaaacua cagagugacu     2400

ucugacaaua agguacagua ugaugugguu uuucaugggg uccucaccga caacgcagau     2460

auauccaaua acaaagcucc caucgccaag gugacgggac cuucaaccgg ugcggugggc     2520

aggaauauug aguucagugg gaaagacagc aaggaugaag acggaaaaau cgucucguac     2580

gauugggacu uuggcgacgg ugccacaucc cgugggaaga acucuguuca cgcuuacaag     2640

aaagcaggca cuuauaaugu gacccugaag gugacagaug acaaaggagc cacugcuacc     2700

gagagcuuca cgauugaaau caagaacgaa gauacaacca cuccaauaac aaaagagaug     2760

gagcccaaug acgauauuaa ggaagccaac ggcccgaucg uagagggggu caccgugaag     2820

ggagaccuua acggcucaga ugacgcagau acuuuuuacu ucgacguuaa agaagauggu     2880

gacgugacca uugaguugcc uuauaguggg uccucuaauu uuacauggcu ggucuacaag     2940

gagggagacg aucagaacca caucgcgagc ggcauagaca aaaauaacuc caaggugggu     3000

acguucaaau caaccaaggg ccggcauuau guuuucaucu acaagcacga uagcgccagu     3060

aauauuucuu auucccucaa caucaaaggg cugggaaaug aaaaguuaaa agagaaggaa     3120

aacaaugaca gcucggauaa agcuacugug auucccaacu uuaauacaac caugcagggc     3180

ucacugcuug gggacgauuc ucgagacuac uacaguuucg agguaaagga agagggagag     3240

gucaacaucg aauuggauaa gaaagacgag uuuggcguga cauggacucu ccauccagaa     3300

uccaauauaa acgauagaau uaccuauggu caaguggacg ggaauaaggu cagcaacaaa     3360

guuaagcuga ggccuggaaa auacuaucua cugguguaca aguauucugg cagcgguaau     3420

uacgagcucc gcguaaacaa gugaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  1672
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt3)

<400>  1672
gggagaaagc uuaccaugaa cuuccugaag aucauucuca auagaggcaa aaccaugaag       60

aggaaaugcc uuagcaagcg gcugauguug gccauaacaa uggcuacuau cuuuacggug      120

aacuccaccu uacccauuua cgcagccguc gacaaaaaua acgcgacagc ugccguucag      180

aaugagucua agcgcuauac ugugucauac cugaagaccc uaaacuauua cgaucucgua      240

gaccugcuug ugaaaacaga aaucgagaau cugccugauu uguuccaaua uaguagcgac      300

gcaaaggaau uuuacgggaa caaaacccga auguccuuca uuauggauga gaucggacgu      360

agagccccac aguauacuga aauagaccac aaggguaucc cgacacucgu cgaggugguu      420

agggcuggcu uuuaccuggg guuccauaau aaagagcuga acgaaauuaa uaagcggucu      480

uuuaaggagc gcgugauccc cucgauucuc gcaauccaga aaaacccuaa uuucaaguua      540

ggaaccgaag uccaggauaa aauaguguca gccacgggcc ugcuugcugg uaacgagacu      600

gccccacccg agguaguuaa uaacuuuacc ccuauuuugc aagacuguau caagaacauu      660

gauagauacg cgcuggacga ucuaaaaagc aaggcacucu ucaaugugcu ggccgcucca      720

acauaugaca ucacugaaua ccuuagggcc accaaagaga agcccgaaaa cacaccuugg      780

uaugggaaga ucgauggauu uauuaaugag cugaaaaagu uggcacucua cggcaaaaua      840

aacgacaaua acaguuggau cauugacaau ggcaucuauc acauagcucc acuggggaag      900

uuacauucca acaauaaaau uggaaucgaa acccugacgg aggucaugaa gguguacccg      960

uaucucucua ugcagcaccu ucagagcgcc gaucagauca agcggcauua cgacuccaaa     1020

gaugcggagg guaacaagau uccccuggac aaauucaaga aagaaggcaa ggagaaguac     1080

ugcccuaaaa cuuauacauu ugaugacggg aaggugauca uuaaagccgg agcacgcguc     1140

gaagaggaaa agguuaaacg auuguacugg gcuucaaagg aggugaauag ucaauucuuc     1200

agaguauaug gcauagauaa gccacuagag gaagguaacc ccgacgauau ccugaccaug     1260

gugauuuaca auagcccuga ggaauauaaa cucaacucug uccuguacgg guaugacacu     1320

aauaacggag gcauguacau cgagccagaa ggcacauuuu ucaccuacga gagggaggcc     1380

caggaaucca cguauacccu ugaggaacug uuucggcacg aguacacaca cuauuugcag     1440

gggcguuacg cugugcccgg acaguggggu cgcacuaagc ucuaugauaa cgacagacug     1500

accugguacg aggaaggcgg ggccgaguua uucgcaggau caacaaggac uagcggcauc     1560

cugccgcgga aaaguauugu uucuaauaua cauaacacca cacgaaauaa ccgcuauaag     1620

cuauccgaca ccgugcacag caaauacggu gccucguuug aguucuacaa uuaugcuugu     1680

auguuuaugg auuacaugua uaacaaggac auggggaucc ucaauaaacu gaacgaucuu     1740

gcgaagaaua acgacgucga uggcuacgac aauuauauua gagauuuguc uuccaacuac     1800

gcacugaaug acaaguauca agaucauaug caggaaagga ucgacaacua cgaaaaucuc     1860

acugugccuu ucguagccga ugacuaccug guucggcacg cuuauaaaaa ccccaacgag     1920

auuuacucag agaucaguga aguggccaaa cuuaaggaug caaagagcga ggucaaaaag     1980

ucccaguauu uuucuacguu cacacugcgc ggaagcuaca ccggcggggc cucaaaggga     2040

aaauuggaag accaaaaggc uaugaauaaa uuuauagacg auagucucaa gaaacuggac     2100

acuuauuccu ggagcgguua caagaccuua acagccuauu ucaccaacua caagguggau     2160

ucuucaaaua gagucacuua cgacgugguu uuucacggcu aucugccaaa cgagggggau     2220

aguaaaaaua gccuaccuua cggaaagauc aacggcacau auaaagguac ggaaaaggag     2280

aaaauuaagu ucuccucuga ggggucguuc gaccccgaug gcaagaucgu gagcuacgaa     2340

ugggacuuug gagauggcaa uaaauccaac gaggaaaauc cagagcauuc auaugacaag     2400

guagggaccu acacugucaa acucaaggug acagaugaca aaggagaaag uucuguuagc     2460

accacaacug cagagauuaa ggaucugucc gagaacaaac uucccgugau cuauaugcac     2520

gucccuaagu caggugcguu gaaucagaag gugguauucu acggcaaagg gaccuacgac     2580

ccagacggaa gcauagcugg cuaucagugg gauuuuggug acgggucuga uuucuccagu     2640

gaacagaacc cgagccaugu guacacgaag aaaggcgagu auaccguuac acugaggguc     2700

auggacucuu ccggacaaau gucagaaaag acuaugaaaa uuaagaucac cgaucccgug     2760

uacccuauug gcacagagaa ggagccaaau aacaguaaag aaacugccag cgggcccauc     2820

gugccuggaa uaccagucuc gggcaccauc gagaauacgu ccgaccagga uuauuuuuac     2880

uucgacguua uuacacccgg ugaagugaag aucgauauua acaaacucgg guauggaggc     2940

gcaaccuggg ugguauacga cgagaacaau aacgccgucu cuuacgcuac ugaugacggu     3000

cagaaucuga gcggcaaguu uaaagccgac aagccggggc guuauuacau ccacuuauau     3060

auguucaacg gaucauacau gccuuaucgg auaaauauug aaggcagugu ggggcgauga     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  1673
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt3)

<400>  1673
gggagaaagc uuaccaugaa gagaaaaugc cugagcaaga ggcucaugcu ugccaucacc       60

auggcuacaa uuuucacugu gaacuccacg cugcccauau acgcagccgu cgacaaaaau      120

aacgcgaccg cugccguuca gaaugagucu aagcgguaua cagugucaua cuugaaaacu      180

uuaaacuauu acgaucuggu agaccuacuc gugaagaccg aaaucgagaa ucugccugau      240

cuuuuucaau auaguagcga cgcaaaggag uucuacggca acaaaacacg cauguccuuu      300

auuauggaug aaaucgggcg acgugcccca caguauaccg aaauugacca caagggaauc      360

ccgacucugg ucgagguggu uagagcuggu uucuacuugg gcuuucauaa uaaagagcuc      420

aacgaaauaa auaagagguc uuucaaagag cgggugaucc ccucgauucu ggcaauccag      480

aagaacccua auuuuaagcu ggggacagaa guccaggaua aaauuguguc agccaccgga      540

cucuuagcug gcaacgagac ggccccaccc gagguaguua auaacuucac uccuauccug      600

caagacugua uaaagaauau ugaucgcuac gcgcuugacg auuugaaaag caaggcacug      660

uuuaacgugc uagccgcucc aaccuaugac aucacagaau accucagagc cacuaaagag      720

aagcccgaaa acaccccuug guaugguaaa auugaugggu ucaucaauga gcugaagaag      780

cuggcacugu acggaaaaau caacgacaau aacaguugga uuauagacaa uggcaucuau      840

cacauugcuc cauugggcaa gcuccauucc aacaauaaaa ucgggauaga aacacugacc      900

gaggucauga agguguaccc guauuuaucu augcagcacc uucagagcgc cgaucagauu      960

aaaaggcauu acgacuccaa ggaugcggag ggaaacaaga ucccccucga caaauuuaag     1020

aaagaaggua aggagaaaua cugcccuaag acguauacuu ucgaugacgg caaggugauc     1080

auuaaagccg gggcacgggu cgaagaggaa aagguuaaac gccuuuacug ggcuucaaag     1140

gaggugaaua gucaauuuuu ccgaguauau ggaaucgaua aaccacugga ggaaggcaac     1200

cccgacgaua uuuugacaau ggugauauac aauagcccug aggaauauaa gcuaaacucu     1260

guccuguacg guuaugacac caauaacggg ggaauguaca ucgagccaga aggcacuuuc     1320

uuuacauacg agagagaggc ccaggaaucc accuauacgc ucgaggaacu guucaggcac     1380

gaguacaccc acuaucuuca gggccgguac gcugugcccg ggcagugggg acguacaaag     1440

cuguaugaua augaccgcuu gacuugguac gaggaaggug gcgccgagcu cuuugcaggg     1500

ucaaccagaa caagcggcau ucugccgagg aaaaguaucg uuucuaacau ccauaacacu     1560

acccggaaua accgauauaa guuauccgac acagugcaca gcaaauacgg agccucguuc     1620

gaauuuuaca auuaugcuug uauguucaug gauuacaugu auaacaagga cauggguauu     1680

cugaauaaac uaaacgaucu cgcgaagaau aacgacgucg auggguacga caauuauaua     1740

cgcgaucugu cuuccaacua cgcacuuaau gacaaauauc aagaucauau gcaggagaga     1800

aucgacaacu acgaaaauuu gaccgugccu uuuguagccg augacuaccu gguuaggcac     1860

gcuuauaaga accccaauga gauuuacuca gagaucagug aaguggccaa gcucaaagau     1920

gcaaagagcg aggucaaaaa gucccaguau uucucuacuu uuacgcugcg gggcagcuac     1980

acaggaggcg ccucaaaagg gaaacuugaa gaccaaaagg cuaugaacaa guucauugac     2040

gauagucuga agaaauugga caccuauucc uggagcggau acaagacucu caccgccuau     2100

uuuacaaacu acaaagugga uucuucaaau cgcgucaccu acgacguggu uuuccacggu     2160

uaucugccaa acgagggcga uaguaagaau agcuuaccuu acgggaagau caacggaacu     2220

uauaaaggca cagaaaagga gaaaauaaag uuuuccucug aggguucguu cgaccccgau     2280

gggaaaaucg ugagcuacga augggacuuc ggcgauggaa auaaguccaa cgaggaaaau     2340

ccagagcauu cauaugacaa gguaggcacg uacaccguca aacugaaggu gacugaugac     2400

aaaggggaaa guucuguuag cacaaccaca gcagagauua aggaucuauc cgagaacaaa     2460

cuccccguga ucuauaugca cgucccuaag ucaggagcgc ugaaucagaa agugguauuu     2520

uacgguaagg gcacuuacga cccagacggg agcauugcug gauaucagug ggauuucggc     2580

gacgguucug auuuuuccag ugaacagaac ccgagccaug uguacaccaa gaaaggggag     2640

uauacgguua cccuuagagu cauggacucu uccggccaaa ugucagaaaa gacaaugaaa     2700

aucaagauaa cugaucccgu guacccuauu ggaaccgaga aagagccaaa uaacaguaag     2760

gaaacagcca gcggccccau cgugccuggg auuccagucu cgggaacuau cgagaauacc     2820

uccgaccagg auuauuucua cuuugacguu auaacgcccg gcgaagugaa gaucgauauu     2880

aacaaauugg guuauggggg agcaacaugg gugguauacg acgagaauaa caacgccguc     2940

ucuuacgcua ccgaugacgg ccagaaucug agcgguaagu ucaaagccga caagccgggc     3000

agguauuaca uccaccucua uauguuuaac gggucauaca ugccuuaucg uauuaauauc     3060

gaaggaagug ugggccggug aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  1674
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt3)

<400>  1674
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuucu uuucuccucu       60

gccuacucag uccagaacga gaguaaaaga uauacaguua gcuaccugaa gacuuugaau      120

uauuacgacu uaguggaucu gcuaguaaaa acggaaauug agaaccuccc cgaccuguuu      180

caauauuccu cugaugcuaa ggaguucuac ggcaauaaaa ccaggauguc guuuauaaug      240

gacgaaaucg gccggcgcgc accucaguau acagaaauug aucacaaggg aaucccaacu      300

cuuguggagg ucgugcgagc cgguuucuac cugggcuuuc auaacaagga guugaaugaa      360

auuaacaaac guucauucaa ggagagaguu aucccgagca uacucgcgau ccagaaaaau      420

cccaacuuua agcuggggac cgaagugcag gacaaaauug ucagugcuac aggacugcuc      480

gccggcaaug agaccgcacc uccagaggug guaaacaauu ucacucccau cuuacaagau      540

ugcauuaaga acaucgacag guacgcccug gaugaccuua aguccaaggc uuuguuuaau      600

guucuggcag ccccuacaua ugauauaacc gaauaccuac gggcuacgaa ggagaaacca      660

gaaaacacuc ccugguaugg uaagauugac ggguucauca augagcucaa aaagcuggcc      720

cuuuacggaa aaauuaacga uaacaauucu uggaucaucg acaacggcau uuaucacaua      780

gcgccucugg gcaaguugca uagcaauaac aagaucggga uugaaacccu cacagaggug      840

augaaagucu acccauaucu guccaugcag cacuuacagu cagcagacca gaucaagcgc      900

cauuacgaua guaaagacgc cgagggaaau aagauaccgc uggauaaauu uaagaaggaa      960

gguaaagaga aguacugucc caaaacuuau accuucgacg auggcaaggu gauuaucaaa     1020

gcuggggcca gaguggaaga ggaaaagguc aagaggcucu acugggcaag caaagagguu     1080

aacucucaau ucuuucgggu guauggaauc gacaagccuc uugaggaagg caauccagau     1140

gacauucuga caaugguaau cuacaacucc cccgaggaau auaaacuaaa uucaguguug     1200

uacgguuaug auaccaacaa ugggggaaug uacauugagc cugaaggcac guucuuuacu     1260

uacgagcgcg aggcucagga aagcacauau acccuggagg aacucuuccg acacgaguac     1320

acucacuauc ugcagggcag auacgccguc ccagggcagu ggggaaggac aaaacuuuau     1380

gacaacgauc ggcugaccug guacgaggaa gguggcgcgg aguuguuugc cgggaguacg     1440

cguaccucug gaauacuccc ccgcaaaucc aucgugagca auauucauaa cacaacuaga     1500

aauaacaggu auaagcuguc ggacaccguu cacucuaagu acggcgcauc cuucgaauuu     1560

uacaacuaug cuugcauguu cauggacuac auguauaaua aagauauggg uaucuuaaac     1620

aagcugaaug accuagccaa aaacaaugau guggacgggu acgauaacua uauccgggac     1680

cucucaagua auuacgcucu gaacgauaag uaucaagacc auaugcagga gcgaauugau     1740

aauuacgaaa accuuacagu cccguuugug gccgacgauu acuugguacg ccacgcauau     1800

aaaaauccua acgagauaua cagcgagauc uccgaaguug ccaagcugaa agacgcuaag     1860

ucugagguga agaaaagcca guauuucuca acuuuuaccc ucagaggcag uuacacagga     1920

ggcgcgucca aggggaaacu ggaagaucaa aaggcaauga auaaauucau ugacgacagc     1980

cuuaagaagc uggauaccua uucuugguca ggauacaaaa cuuugacggc cuauuuuaca     2040

aacuacaagg ucgacaguag caauagggug accuacgaug ucguguucca cgguuaucuc     2100

cccaacgagg gcgacuccaa aaacucucug ccauacggga agaucaaugg aacuuauaaa     2160

ggcaccgaaa aggagaagau uaaauucucg agcgaggguu ccuuugaucc ugacgggaag     2220

aucguuucau acgaauggga uuucggcgac ggaaacaaaa guaaugagga aaaccccgag     2280

cauucuuaug auaagguggg cacauacacc guaaaauuaa aggucacuga cgauaagggg     2340

gaaagcuccg ugucaacaac gaccgcugag auaaaagacc ugagcgagaa uaagcuacca     2400

guuaucuaua ugcacgugcc caaaucugga gcccucaacc agaaggucgu guuuuacggu     2460

aaaggcacuu acgauccuga cggguccauu gcaggauauc agugggacuu cggcgauggu     2520

agugacuuua gcucugaaca gaauccaucc cauguauaca caaagaaagg ggaguauacc     2580

gugacacugc ggguuaugga uucaaguggc caaaugagcg aaaagacuau gaagaucaaa     2640

auuaccgacc cggucuaccc caucggaacg gagaaggagc cuaacaauuc gaaagaaacc     2700

gccuccggcc caauagugcc cgggauuccu gugucuggaa caaucgagaa cacuagcgau     2760

caggacuauu ucuacuuuga ugucauuacc ccaggcgaag uuaagaucga cauaaauaaa     2820

cuugguuaug ggggagcuac auggguggug uacgaugaga acaauaacgc cguaucauac     2880

gcaacugacg auggccagaa uuugaguggu aaguucaagg cggacaaacc cggccgcuau     2940

uacauccacc uguauauguu uaacgggucc uacaugccgu auagaauuaa caucgaagga     3000

ucugucggga ggugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1675
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt3)

<400>  1675
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuucu uuucuccucu       60

gccuacucaa ugaaaagaaa gugccugagu aaaagguuga uguuagcuau uacaauggca      120

acuauauuua cggucaacag cacccugccc aucuaugccg cgguugacaa gaauaacgcu      180

acagccgcac ggcgccgacg uaaaagagug cagaaugagu ccaagaggua cacuguaucu      240

uaucuaaaga cccucaacua cuaugaucug guggaccuuc uggucaaaac agaaauugag      300

aauuugccug aucucuucca auacucguca gacgccaagg aauuuuaugg caacaaaacc      360

cggaugagcu ucaucaugga ugagauuggg cgcagagcuc cacaguacac ugaaaucgac      420

cacaagggaa uaccgacacu gguggagguu gugagggcag guuuuuaccu gggcuuccau      480

aauaaagagc ucaacgaaau caauaagcgg aguuuuaagg agcgcgucau ucccuccauc      540

uuagccauuc agaaaaaccc uaauuucaag cuggggaccg aagugcagga uaaaaucgua      600

ucugcuacgg gacuuuuggc cggcaacgag acugcgccac ccgagguugu gaauaacuuu      660

accccuauac ugcaagacug uauuaagaau aucgaucgau augcacuaga cgaucucaaa      720

agcaaggccc uguucaacgu ccuugcugcc ccaacauacg acauuacuga auaucugaga      780

gcaaccaaag agaagcccga aaacacaccu ugguacggua agaucgaugg guuuaucaau      840

gaguugaaaa agcucgcucu guauggaaaa auuaacgaca auaacuccug gauaaucgac      900

aauggcauuu accacaucgc cccauuaggc aagcugcauu caaacaauaa aauagggauu      960

gaaacccuca cggaggugau gaagguguau ccguaccuua guaugcagca ucugcagagc     1020

gcggaucaga ucaagaggca cuacgacucu aaagaugccg agggaaacaa gauccccuug     1080

gacaaauuca agaaagaagg uaaggagaag uauugcccua aaacuuacac auucgaugac     1140

ggcaagguca uuaucaaagc aggggcucgg guugaagagg aaaaggugaa acgucuauau     1200

ugggccucca aggagguaaa uucacaauuu uuccgcgugu acggaauuga uaagccacug     1260

gaggaaggca accccgacga uauacucacc auggucaucu auaauagccc ugaggaauac     1320

aaacugaaca gugugcuuua ugguuacgac acuaauaacg ggggaaugua cauugagcca     1380

gaaggcacau uuuucaccua ugagagagag gcucaggaau cuacguacac ccuggaggaa     1440

uuguuuaggc acgaguauac acacuaccuc cagggccggu augccguucc cgggcagugg     1500

ggacgaacua agcuguacga uaaugaccgc uuaaccuggu augaggaagg uggcgcagag     1560

cuguucgccg gguccacaag aacuagcgga auccuaccga ggaaaucgau cgugucuaac     1620

auucauaaca ccacacggaa uaaccgcuac aagcucuccg acaccgucca cucaaaauac     1680

ggcgcuaguu uugaguucua uaauuacgcg uguauguuua uggauuauau guacaacaag     1740

gacaugggua uacugaauaa acuuaacgau uuggcaaaga auaacgacgu ggauggguau     1800

gacaauuaca ucagagaucu gagcuccaac uaugcccuca augacaagua ccaagaucau     1860

augcaggaaa ggauugacaa cuacgaaaau cugacuguac cuuucguugc ugaugacuau     1920

cuugugcguc acgccuacaa aaaccccaau gagaucuauu cugagauuag cgaagucgca     1980

aagcugaaag augccaaguc agaggugaaa aagagucagu acuuuuccac guucacauug     2040

cggggcagcu auaccggagg cgcuucuaag gggaaacucg aagaccaaaa ggccaugaac     2100

aaauuuaucg acgauucacu gaagaaauua gacacuuaca guuggagcgg auauaagacc     2160

cugacagcau acuucaccaa cuacaagguc gauuccucua aucgagugac uuaugacguu     2220

guguuccacg guuaccuacc aaacgagggc gauucgaaaa auagccuccc uuaugggaag     2280

auaaacggaa cauacaaagg cacggaaaag gagaaaauca aguuuuccuc agaggguagu     2340

uucgaccccg augggaagau uguaucuuau gaaugggacu uuggcgaugg aaauaaaagc     2400

aacgaggaaa auccagagca uuccuacgac aaggucggca ccuauacugu gaaacugaag     2460

guuacagaug acaaagggga aucaagcgug ucuaccacaa cugcggagau caaggaucuu     2520

uccgagaaca aauugcccgu cauuuacaug cacgugccua agaguggagc ucugaaucag     2580

aagguagugu ucuacgguaa aggcaccuau gacccagacg ggagcaucgc cggauaccag     2640

ugggauuuug gcgacgguuc ugauuucucc ucagaacaga acccgaguca uguuuauacg     2700

aagaaagggg aguacaccgu cacacucaga gugauggaca gcucgggcca aauguccgaa     2760

aagacuauga aaauaaagau uaccgauccc guguauccua ucggaacaga gaaggagcca     2820

aauaacucua aagaaacugc aagcggcccc auugucccug ggaucccagu uucaggaacc     2880

auagagaaua cgagugacca ggauuacuuu uauuucgacg ugaucacacc cggcgaagug     2940

aagauugaua ucaacaaacu ggguuacggg ggagccaccu ggguagucua cgacgagaau     3000

aacaacgcug uguccuaugc cacugaugac ggccagaauu uaucugguaa guuuaaagca     3060

gacaagccgg gcagguacua uauucaccug uacauguuca acgggagcua uaugccuuac     3120

cgcaucaaua uagaaggauc cguuggccgg ugaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  1676
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt3)

<400>  1676
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuugg ggcugcauuu       60

gccaugcccc ugccuccaca cccgggacau cccgguuaca uuaacuucag cuaugaggug      120

uugacaccuu uaaaguggua ccaguccaua agaccacccu auccuucuua cggcuaugaa      180

ccaaugggag gguggcugca ccaucaaauc auucccgucc uaucacagca gcacccucca      240

acucauacgc uccagccgca ccaccauauc cccguugugc cugcgcaaca gccaguaauu      300

ccccagcagc cuaugaugcc agugcccggc caacacagua ugaccccgau ccagcaucac      360

cagccuaauc ugcccccucc agcucagcaa cccuaccagc cacagcccgu ccaaccucag      420

ccacaccagc cgaugcagcc ccaaccucca gugcauccca ugcagccucu uccaccccag      480

ccgccucugc cacccauguu uccuaugcag cccuugccac cuaugcuccc cgaccugaca      540

cuggaggccu ggccaagcac ugauaaaacc aagagggaag agguugacug aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  1677
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt3)

<400>  1677
gggagaaagc uuaccaugcc ccugccucca cacccgggcc aucccgggua caucaacuuc       60

agcuaugagg ugcucacccc ucuuaagugg uaccagucca uuagaccacc cuauccuucu      120

uacggauaug aaccaauggg uggcugguga ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  1678
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt3)

<400>  1678
gggagaaagc uuaccaugcc ccugccucca cacccgggcc aucccgggua caucaacuuc       60

agcuaugagg ugcucacccc ucuuaagugg uaccagucca uuagaccacc cccuaugcug      120

ccagacuuga cauuagaagc cuggcccucu acugauaaaa cgaagaggga ggaagucgac      180

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  1679
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt3)

<400>  1679
gggagaaagc uuaccauggc cgugauggcu cccagaaccc ugguccuccu ucugagcggc       60

gcauuggccu uaacacagac uugggcgaug ccucugccac cgcaccccgg gcauccugga      120

uacaucaacu ucuccuauga gguucuaacg ccacucaagu gguaccaauc uauuaggccc      180

ccuuauccau cauacgguua ugaacccaug ggcggguggu gaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  1680
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt3)

<400>  1680
gggagaaagc uuaccauggc cgugauggcu cccagaaccc ugguccuccu ucugagcggc       60

gcauuggccu uaacacagac uugggcgaug ccucugccac cgcaccccgg gcauccugga      120

uacaucaacu ucuccuauga gguucuaacg ccacucaagu gguaccaauc uauuaggccc      180

ccuccaaugc ugcccgaccu uacccuggag gcuuggccuu caacagauaa aacuaagcgg      240

gaagaagugg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  1681
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt3)

<400>  1681
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccucguggg ggcugcauuu       60

gccaugcccc uuccuccaca cccgggacau cccgguuaca uuaacuucag cuaugagguc      120

cugacaccuu ugaaguggua ccaguccaug auaagaccac ccuauucuuc auacggcuau      180

gaaccuaugg gagggugguu acaccaucaa aucauuccag uugugaguca gcagcacccc      240

cugacucaua cgcuacagag ccaccaccau aucccuguag ugccagcgca acagccgagg      300

guccggcagc aggcucucau gcccgugccu ggccaacagu ccaugacccc aacacagcac      360

caucagccca aucugccucu uccagcccaa cagcccuuuc agccgcaacc uguucagccc      420

cagccacacc agccuaugca accccagcca cccgugcagc cuaugcagcc acuguugccg      480

caacccccuc ucccacccau guucccucug cgcccacugc ccccgauucu cccugacuua      540

caccuggagg cauggccagc cacugauaaa accaagcagg aagaggucga cugaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  1682
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt3)

<400>  1682
gggagaaagc uuaccaugcc ccugccucca cacccgggcc aucccgggua caucaacuuc       60

agcuaugagg ugcucacccc ucuuaagugg uaccagucca ugauuagacc acccuauucu      120

ucauacggau augaaccuau ggguggcugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1683
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt3)

<400>  1683
gggagaaagc uuaccaugcc ccugccucca cacccgggcc aucccgggua caucaacuuc       60

agcuaugagg ugcucacccc ucuuaagugg uaccagucca ugauuagacc acccccuaua      120

cugccagacu ugcacuuaga agccuggccc gcuacagaua aaacuaagca agaggaaguc      180

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1684
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt3)

<400>  1684
gggagaaagc uuaccauggc cgugauggcu cccagaaccc ugguccuccu ucugagcggc       60

gcauuggccu uaacacagac uugggcgaug ccucugccac cgcaccccgg gcauccugga      120

uacaucaacu ucuccuauga gguucuaacg ccacucaagu gguaccaauc uaugauuagg      180

cccccuuauu caaguuacgg uuaugaacca augggcgggu ggugaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1685
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt3)

<400>  1685
gggagaaagc uuaccauggc cgugauggcu cccagaaccc ugguccuccu ucugagcggc       60

gcauuggccu uaacacagac uugggcgaug ccucugccac cgcaccccgg gcauccugga      120

uacaucaacu ucuccuauga gguucuaacg ccacucaagu gguaccaauc uaugauuagg      180

cccccuccaa uacugcccga ccuucaccug gaggcuuggc cugccaccga uaaaacaaag      240

caggaagaag uggacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1686
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt3)

<400>  1686
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuugg ggcugcauuu       60

agcaugcccc ugccuccaca cccgggacau cccgguuaca uuaacuucuc cuaugaggug      120

uugacaccuu uaaaguggua ccagaauaug auaagacacc cauauacuuc uuacggcuau      180

gaacccaugg gaggguggcu gcaucaccaa aucauuccug ucguuucaca gcagacgcca      240

cagagucaug cccuacaacc ccaccaccau aucccuaugg ugccagcgca gcagccgggc      300

auuccccagc aaccuaugau gccacucccc ggucagcaca gcaugacccc uacacagcau      360

caccagccaa accugccccu uccggcucaa cagccuuuuc agccccaacc aguacagccu      420

cagccccacc agccacugca accccagucc ccuaugcauc caauccagcc guugcucccc      480

cagccuccac ugcccccuau guucucuaug caaucgcugc ucccagacuu accccuggag      540

gccuggccgg caacugauaa aaccaagagg gaagaggugg acugaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1687
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt3)

<400>  1687
gggagaaagc uuaccaugcc ccugccucca cacccgggcc aucccgggua caucaacuuc       60

agcuaugagg ugcucacccc ucuuaagugg uaccagaaua ugauuagaca cccauauaca      120

uccuacggau augaacccau ggguggcugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1688
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt3)

<400>  1688
gggagaaagc uuaccaugcc ccugccucca cacccgggcc aucccgggua caucaacuuc       60

agcuaugagg ugcucacccc ucuuaagugg uaccagaaua ugauuagaca cccaucccug      120

uugcccgacu uaccucugga agccuggcca gcuacagaua aaacuaagag ggaggaaguc      180

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1689
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt3)

<400>  1689
gggagaaagc uuaccauggc cgugauggcu cccagaaccc ugguccuccu ucugagcggc       60

gcauuggccu uaacacagac uugggcgaug ccucugccac cgcaccccgg gcauccugga      120

uacaucaacu ucuccuauga gguucuaacg ccacucaagu gguaccaaaa uaugauuagg      180

caccccuaua ccucuuacgg uuaugaaccu augggcgggu ggugaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1690
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt3)

<400>  1690
gggagaaagc uuaccauggc cgugauggcu cccagaaccc ugguccuccu ucugagcggc       60

gcauuggccu uaacacagac uugggcgaug ccucugccac cgcaccccgg gcauccugga      120

uacaucaacu ucuccuauga gguucuaacg ccacucaagu gguaccaaaa uaugauuagg      180

caccccucuc ugcuuccuga ccugccauug gaggcuuggc ccgccaccga uaaaacaaag      240

cgggaagaag uggacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1691
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt3)

<400>  1691
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuugg ggcugcauuu       60

agcaugcccc ugccuccaca cccgggacau cccgguuaca uuaacuucuc cuauauaaga      120

cacccuuaca caucuuaugg cuacgagcca augggagggu gguugcauca ccagaucauu      180

cccguggucu cacaacagac uccucagagu caugccuuac agccacacca ccauaucccc      240

augguuccug cgcaacagcc aggcauuccg cagcagccca ugaugccucu gccaggucaa      300

cacagcauga cgcccaccca gcaucaccag ccuaaucuac cacuccccgc ucagcaaccg      360

uuucagccuc agcccgugca accacagccu caccagcccc ugcagccaca aucccccaug      420

cauccuaucc agccacuucu gccgcagccc ccuuugccac ccauguucuc uaugcagucg      480

cuccugccug accugccacu cgaagccugg cccgcaacag auaagacuaa aagggaggaa      540

guagacugag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  1692
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt3)

<400>  1692
gggagaaagc uuaccauggg caccuggauc uucuuugccu gccugcucgg ggcuagccuu       60

gcaaugcccc ugccuccaca cccgggacau cccgguuaca uuaacuucuc cuaugaggug      120

uugacaccuu uaaaguggua ccagaauaug auaagacacc cauauacuuc uuacggcuau      180

gaacccaugg gaggguggcu gcaucaccaa aucauuccug ucguuucaca gcagacgcca      240

cagagucaug cccuacaacc ccaccaccau aucccuaugg ugccagcgca gcagccgggc      300

auuccccagc aaccuaugau gccacucccc ggucagcaca gcaugacccc uacacagcau      360

caccagccaa accugccccu uccggcucaa cagccuuuuc agccccaacc aguacagccu      420

cagccccacc agccacugca accccagucc ccuaugcauc caauccagcc guugcucccc      480

cagccuccac ugcccccuau guucucuaug caaucgcugc ucccagacuu accccuggag      540

gccuggccgg caacugauaa aaccaagagg gaagaggugg acugaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1693
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt3)

<400>  1693
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuugg ggcugcauuu       60

agcaugcccc ugccuccaca cccgggacau cccgguuaca uuaacuucuc cuaugaggug      120

uugacaccuu uaaaguggua ccagaauaug auaagacacc caucucugcu acccgaccuc      180

ccucuggaag ccuggccagc gacugauaaa acgaagaggg aggaagucga cugaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  1694
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt3)

<400>  1694
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuugg ggcugcauuu       60

agcaugcccc ugccuccaca cccgggacau cccgguuaca uuaacuucuc cuaugaggac      120

uuguacuuag aagccauaag aaucgauagg acagcguuug ugcugacucc ucuaaagugg      180

uaucagaaua ugauucggca cccauacacg ucuuauggcu acgagcccau gggagggugg      240

cuccaucacc aaaucauucc ugucguuuca cagcagaccc cacagaguca ugcucugcaa      300

ccccaccacc auaucccuau ggugccagcc cagcagccgg gcauacccca gcaaccuaug      360

augccacuuc ccggucagca cagcaugaca ccuacucagc aucaccagcc aaaccugccc      420

uugccggcac aacagccuuu ccagccccaa ccaguacagc cucagcccca ccagccacuc      480

caaccccagu ccccuaugca uccaauccag ccgcugcugc cccagccucc auuacccccu      540

auguuuucua ugcaaucgcu ccugccagac cuucccuugg aagccuggcc ggcuaccgau      600

aaaacaaagc gcgaggaagu ggacugagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  1695
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt3)

<400>  1695
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuugg ggcugcauuu       60

agcaugcccc ugccuccaca cccgggacau cccgguuaca uuaacuucuc cuaugaggug      120

uugacaccuu uaaaguggua ccagaauaug auaagacacc caacucccca aucucaugcc      180

cugcagccuc accaucacau cccaaugguc cccgcgcagc agccuggcau uccacaacag      240

ccgaugaugc cccuaccugg gcagcacuca augacgccaa cccagcauca ccaacccaac      300

cucccucugc cagcucagca gcccuuucag ccgcaaccug uucagcccca gccacaucaa      360

ccucuucagc cccagagucc aaugcacccc auccagccuc uguugccaca accgccccuc      420

ccuccaaugu ucagcaugca gucccugcug cccgaccucc cuuuagaagc cuggccagca      480

acagauaaaa cuaagaggga ggaaguggac ugaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  1696
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt3)

<400>  1696
gggagaaagc uuaccaugcc ccugccucca cacccgggcc aucccgggua caucaacuuc       60

agcuaugagg ugcucacccc ucuuaagugg uaccagaaua ugauuagaca cccauauaca      120

uccuacggau augaacccau ggguggcugg cugcaucacc aaauaauccc ugucguuucu      180

cagcagacuc cacagucaca ugccuugcaa ccccaccacc auauuccuau ggugccagcu      240

cagcagccgg ggauccccca gcaaccuaug augccauuac ccggacagca caguaugacg      300

ccuacccagc aucaccagcc aaaccugccc cuaccggcac aacagccuuu ucagccccaa      360

ccaguacagc cucagcccca ccagccacuc caaccccaga gcccuaugca uccaauucag      420

ccgcugcuuc cccagccucc acugcccccu auguucucca ugcaaucuuu gcucccagac      480

cugccccugg aggccuggcc ggcgacagau aaaacuaaga gggaagaggu ggacugagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  1697
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt3)

<400>  1697
gggagaaagc uuaccaugcc cggcguggcc agacugccuc uccuucuggg guuguuacug       60

cuaccaaggc cgggacggcc ccucgaccug gcugauuaca ccuaugaccu ugcagaggaa      120

gaugacagcg agccucugaa cuacaaggau ccaugcaaag ccgcggcuuu cuugggugac      180

aucgcccucg augaagagga ccugcgcgca uuucaggucc aacaggccgu ugaucugcga      240

cgucacacag cuagaaaguc cucuauuaaa gcagccgugc ccggcaauac uucaacgccu      300

aguugucaga gcaccaacgg gcagccacaa aggggagcuu gcggccggug gcgcgguaga      360

uccaggucuc ggcgcgccgc gacaucgcga cccgaaagag uauggccuga cggggugaua      420

ccauucguca ucggaggcaa uuuuacuggc ucacagaggg caguguuccg gcaggccaug      480

cgucauuggg agaagcacac cuguguuaca uuucucgagc gcaccgauga agacagcuau      540

auuguguuca cuuacagacc gugcgggugu ugcaguuaug ucggaaggcg ggguggcggg      600

ccccaggcua ucuccauugg aaagaacugu gauaaguuug gcaucguggu acaugaguua      660

ggucacguug ugggguucug gcaugaacac acacgaccug accgcgacag acacgucucu      720

auagugaggg agaauaucca accaggacag gaguacaacu uucugaagau ggaaccccag      780

gagguggaaa gccuuggcga gaccuaugau uucgacucca uuaugcauua cgcccggaau      840

acguuuucac gcggcaucuu cuuggauacu auugucccua aauacgaagu uaacggggug      900

aagccaccca ucggacagag aaccaggcug aguaaaggug acauagcaca agcucguaag      960

cuauauaaau gcccggccug uggcgagaca cuccaggaua gcacugggaa uuuuucuucc     1020

ccugaguacc ccaacggaua uucagcgcac augcauugcg uauggcggau uagcgugacc     1080

ccaggcgaaa agaucauucu gaauuucaca agucuugacc uguaccgauc uagauugugu     1140

ugguaugauu acgucgaggu gagggacggu uucuggcgca aggccccucu ccgggggaga     1200

uuuugcggcu ccaaacugcc cgaaccaauc guuagcaccg auucgagguu auggguggag     1260

uuccgaucuu ccucaaacug ggucggaaag ggcuuuuucg caguguauga agcuaucugc     1320

gggggagacg uuaaaaagga uuacggucac auucagaguc ccaauuaccc ugacgacuau     1380

cgcccaagca aaguauguau auggcggauc caaguguccg agggcuuuca cgucgggcug     1440

acguuccagu cuuuugagau ugaacgucau gauagcugcg ccuacgacua ucucgaggug     1500

agagauggac acucagaaag uuccacucuu aucggcaggu acugugguua ugagaagccg     1560

gacgauauaa aaagcacauc uucacgccug ugguugaagu ucgucaguga cgggagcauu     1620

aacaaggcug gcuuugccgu gaauuucuuu aaagaaguug augagugcuc ccggcccaac     1680

agaggaggcu gugagcagag gugccuaaac acccuggggu cuuacaagug uucgugcgac     1740

ccuggauaug aacucgcacc agauaaacga cgcugugagg ccgcuugcgg uggcuuccug     1800

acuaaacuua augggagcau cacauccccc ggauggccua aagaauaccc acccaacaag     1860

aauuguaucu ggcagcuggu ggcgccgacc caauaccgga uuucauugca guuugacuuc     1920

uucgagacgg agggcaacga uguaugcaag uaugacuuug ucgaagugag aaguggucuc     1980

accgcagauu cuaaacugca ugggaaguuc ugcggcagcg agaaaccuga aguuaucaca     2040

ucccaguaca auaacaugag gguggaguuu aagucagaca auacugucag caaaaaggga     2100

uucaaggccc acuuuuucuc ugacaaagau gaauguucca aggacaacgg cgggugccag     2160

caagauugug ugaauaccuu uggaaguuau gagugccagu gucguagcgg cuucguauua     2220

caugacaaca aacacgauug caaggaggcu gguugugacc acaaagugac aucuacuucc     2280

gggaccauua caucaccaaa uuggcccgau aaguacccua guaagaaaga augcaccugg     2340

gccauaagcu cgacucccgg acaucgcguu aagcugacgu uuauggagau ggacaucgaa     2400

ucccagccag agugugcaua ugaucaccua gaagucuucg acggccggga ugccaaagcu     2460

ccugugcucg guagauuuug cggcucuaag aaacccgagc cagugcuggc cacagggagc     2520

aggauguucc uucgauuuua cucagacaac aguguccagc ggaagggauu ccaagcaucc     2580

caugcgaccg aguguggcgg gcagguucgc gcugauguga aaacuaagga cuuguauucu     2640

cacgcccagu ucggagacaa uaacuacccg ggcggugugg auugcgaaug gguaauuguc     2700

gcagaggaag gguacggagu ggagcugguu uuucagaccu ucgaagugga ggaggaaaca     2760

gacugcggcu augauuacau ggagcucuuu gacgguuaug auagcaccgc cccuagacug     2820

ggcagguacu guggguccgg acccccagaa gaggucuauu cagcuggcga cagcgugcuu     2880

guuaaguucc acagugauga cacuaucacg aaaaaggggu uucaucugcg guacacaucu     2940

accaaauucc aagauacuuu gcacucccga aagugaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  1698
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt3)

<400>  1698
gggagaaagc uuaccauggu ggccggcacc agaugccugc ucgcuuugcu guugccccag       60

gucuuacugg gaggggcagc cggucuaguu ccugagcucg gcaggcggaa guucgcggcu      120

gccagcuccg ggcgcccauc uucacaaccg agugacgaag ugcugagcga guuugaacuu      180

cgacuguugu ccauguucgg acucaaacag cgucccacac cuucuagaga ugcaguagug      240

ccacccuaca ugcuggaccu guauaggcgg cacucgggcc agccugguuc accagccccc      300

gaucaucgcc ucgagagagc ugcaagcagg gccaacacug uccggaguuu ucaccaugaa      360

gaguccuuag aggaacugcc ugagacgucu gggaagacca cacgccgauu cuuuuucaau      420

cuuagcucca ucccaacuga agaguuuauu accucagcug agcuucaggu guucagagaa      480

caaaugcagg acgcccuggg aaacaauagu agcuuucacc auaggauaaa caucuacgag      540

auuaucaaac cggcgacagc aaauucuaag uuccccguua cccggcuacu cgauacucgu      600

cuggugaacc agaaugccuc ccgcugggaa ucauuugacg ucaccccugc ugugaugaga      660

uggacagccc agggccacgc aaaccacggc uucguaguug agguggcuca ucuugaagag      720

aaacaagggg ucagcaagag gcacgugcgg auuagucgau cucugcauca ggaugagcac      780

uccuggagcc agauccgccc auugcucgug acguuuggac acgacgguaa gggccauccc      840

cugcacaaaa gagaaaagag gcaggccaaa cauaagcaac ggaaacgcuu aaagucgucu      900

uguaagagac acccucugua ugucgauuuc uccgacguug gguggaauga uuggauagug      960

gcgccacccg gauaccaugc cuucuauugc cacggcgagu guccguuucc ucucgcagac     1020

caccuuaacu caacuaauca ugcuaucgua cagacccugg ugaacagugu caauagcaaa     1080

auucccaagg ccugcugugu gccaacagaa uuguccgcua ucucuaugcu auaccuggau     1140

gagaacgaaa aaguugugcu caagaauuau caggacaugg ucguggaggg uugcgggugu     1200

aggugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  1699
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt3)

<400>  1699
gggagaaagc uuaccaugau ccccggcaac agaaugcuga uggugguccu ccuuugccag       60

guucuguuag ggggagccag ccacgcuucc uugauuccug agaccgguaa gaaaaaggug      120

gcagaaauac aaggccaugc cgggggaagg cggucuggcc agucacacga gcugcuacgc      180

gacuucgaag cgacacuccu gcagauguuu ggucuucgac guagaccaca gccgaguaaa      240

agcgcuguaa uccccgauua caugagggac cuguaucggu ugcaauccgg ggaggaagag      300

gaggaacaga uucauucuac uggacucgag uacccugaac gcccagccuc gagagcaaau      360

acggugaggu cauuccacca ugaggagcac cuggaaaaca uccccggcac cagcgagaau      420

agugccuuuc gguuccuguu uaaccucucc ucuauuccug aaaaugaggu caucagcucc      480

gcugaauuac gccuguuccg agaacaggug gaucagggcc cagacuggga gagaggguuu      540

cacaggauaa acaucuauga gguuaugaag cccccugcag aggugguccc aggacaucuu      600

auuacacggu ugcuggauac ucgucuagug caccauaaug uaacccgcug ggaaacauuc      660

gacguuucac cggccgugcu cagauggacc agggagaaac aacccaacua cggucuggcu      720

aucgaaguca cucaccuuca ccagacacgg acccaucagg gccagcacgu gcgaauuagu      780

cgcagccugc cucaaggguc uggaaauugg gcccaguuga gaccacuccu ggugacguuu      840

ggccaugaug guagggggca cgcguuaacu cggcgcagaa gggcaaagcg uucccccaag      900

caucacucac agcgggcccg aaagaaaaac aaaaauugua gaaggcacag ccuguauguc      960

gacuucagug auguuggaug gaacgacugg aucguggcuc cuccaggcua ccaagccuuu     1020

uauugccaug gcgauugucc cuucccgcuc gcagaccacc uuaauucuac caaccaugcu     1080

auaguacaga cacuggucaa uuccgugaac agcucgauuc cuaaggccug cugugugccc     1140

acugaguugu cugcgaucuc caugcuauac cuggaugagu acgacaaagu ugugcucaag     1200

aacuaucagg aaauggucgu ggaggggugc ggaugucgcu gaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  1700
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt3)

<400>  1700
gggagaaagc uuaccaugcc cggccuaggg agaagggccc aguggcucug cugguggugg       60

ggacuucugu guagcugcug ugguccucca ccguugcggc ccccuuuacc agcugcagcc      120

gcggcugccg caggcgggca acugcuagga gacggcgguu cccccgggcg caccgagcag      180

ccuccacccu cuccucaguc aaguagcgga uuccucuacc gacgucugaa gacacaggag      240

aaaagagaaa ugcaaaagga aauccuuucc gugcugggcu ugccacacag gccgcggccc      300

cuccauggcc ugcagcagcc ucagccaccc gcccugcgcc aacaggagga acagcagcaa      360

cagcagcaac ucccuagagg ggagccaccc ccgggaaggu uaaaaucugc uccucuguuu      420

augcuugauu uguauaacgc acugucggcc gacaaugaug aggacggugc uucagaaggc      480

gagcggcagc agagcuggcc ccacgaagcc gcgaguuccu cucagcgccg acaaccaccu      540

cccggggcag cccauccacu aaacagaaag agccuccugg cucccggauc cggcucaggu      600

ggggccaguc cucuuacuag cgcacaggau ucugcuuucc ugaaugacgc cgauaugguc      660

auguccuuug uuaacuuggu ggaguacgac aaagaguucu caccaaggca gcggcaccau      720

aaggaauuua aguucaaucu cagccagauu ccggagggag aaguagugac ggcggccgag      780

uuucguauau auaaagauug cgucaugggc aguuucaaga accaaaccuu ucugaucucu      840

auuuaccagg uguuacagga acaccagcac cgcgacuccg aucuguuccu ccuugacaca      900

agaguugugu gggcaagcga ggagggcugg cuggaauuug auaucacugc uaccucgaau      960

uugugggucg ugacacccca acauaacaug gggcuacagc ugucuguagu uaccagggac     1020

ggagugcacg uccauccucg ggccgcuggu cucgugggcc gagacgggcc auaugauaaa     1080

cagcccuuca ugguggccuu uuucaagguc uccgagguuc acgugcgcac uacaagauca     1140

gcaaguagca ggcggcgcca gcaauccaga aauaggucua cccagagcca ggacguagcc     1200

cgugugucaa gugcuuccga uuacaacagc ucugaacuga aaacggcgug ucggaagcac     1260

gagcuuuaug ucucauucca agaccuggga uggcaggauu ggauuaucgc accuaagggc     1320

uacgccgcua auuacugcga cggugaaugu aguuuuccau ugaacgccca uaugaaugca     1380

acuaaccacg ccauagugca gacccucguu caucugauga aucccgagua ugugccgaaa     1440

ccuugcugug cuccaacaaa guuaaacgcc aucagcgucc uguacuucga ugacaacucc     1500

aaugugauuc ugaaaaagua ucgaaacaug guaguuagag caugcgggug ucacugagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  1701
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt3)

<400>  1701
gggagaaagc uuaccaugca cgugagaagc cugagggccg cugcacccca uuccuucguc       60

gcccucuggg cgccucuuuu ucuguugcgg ucugcuuuag ccgacuucuc acuggauaac      120

gagguucaca guagcuuuau ccaucgccga cuacguuccc aggaaagaag ggagaugcaa      180

cgggaaauuc ucucuauacu gggccuucca caccgcccga gaccccaucu gcaggggaag      240

cacaauucgg caccuauguu cauguuggac cucuacaacg ccauggcugu ggaggaagga      300

gguggcccag ggggacaggg cuuuucauau cccuacaaag caguauucag cacccagggu      360

ccuccacugg ccagucugca agauucccac uuucucacag acgcugauau ggugaugucu      420

uucgucaauu uaguggagca ugacaaggag uuuuuccacc ccagguauca ucaccgggaa      480

uuucgcuucg aucugagcaa aaucccugag ggggaagccg uuacugcggc agaguuucga      540

auuuacaagg acuauaucag agagagguuc gauaacgaaa cguuccggau uuccguguac      600

cagguccuuc aggagcacuu gggacgugaa ucagaccugu uucuacucga uagucgcacc      660

cugugggcca gcgaggaagg cuggcuugug uucgacauca cagcuacuuc uaaucauugg      720

guaguuaacc caagacacaa ucugggcuug cagcucuccg uggagacccu ggaugggcaa      780

ucaauaaacc cgaaauuagc cggacugauc gguaggcaug gcccccagaa uaagcagccu      840

uuuauggucg cauucuuuaa ggcuacagag gugcacuucc ggagcauucg aaguaccggg      900

ucuaaacagc gcucccaaaa cagaagcaag acucccaaaa aucaggaagc ccucaggaug      960

gcgaacgugg ccgaaaauuc gucuuccgac cagcggcaag caugcaagaa acaugagcuu     1020

uaugucucau uucgcgaccu gggauggcag gauuggauca uugcuccaga gggcuacgcc     1080

gcuuacuauu gugaagguga gugcgccuuc ccuuugaaca guuacaugaa ugcaacaaac     1140

cacgccaucg uucagacccu agugcacuuu auaaacccag agacgguacc caagccgugu     1200

ugcgcuccua cucagcugaa ugcgauuagc gugcucuauu ucgacgauuc cucuaacguc     1260

auccugaaga aauacagaaa uauggugguu agggcaugug ggugccauug aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  1702
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt3)

<400>  1702
gggagaaagc uuaccaugaa ggccagcgcu gcacugcucu gccuucuguu gaccgccgcg       60

gcuuucucuc cccagggcuu agcccaaccu guggggauca acacauccac uacguguugc      120

uacagauuua uuaauaaaaa gauaccaaaa cagaggcugg agucauaucg gcgcaccaca      180

aguagccacu guccgcgaga agcagucauc uucaagacua aacuagacaa ggagauuugc      240

gccgauccca cccagaagug gguucaggac uuuaugaaac aucucgauaa gaaaacacaa      300

accccuaagc ugugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  1703
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt3)

<400>  1703
gggagaaagc uuaccaugcu gcucacccuu aucauucugu ugcccguggu cagcaaguuc       60

uccuuuguuu cuuuaucagc cccucagcac uggaguugcc cagagggcac acuggcuggg      120

aacggaaaua gcacuugugu ggguccggca cccuuccuaa uauuuuccca uggcaacucu      180

aucuucagaa uugacacgga agggaccaau uacgagcaac ucguagugga cgccggaguc      240

ucggugauca uggacuuuca cuauaacgaa aagaggauuu acuggguuga ucuggagcgg      300

cagcuucugc agcgcguguu cuugaauggc ucacgacagg aacgugucug caacaucgag      360

aagaauguga gcgguauggc gauaaacugg aucaaugagg aaguaauuug gaguaaccaa      420

caggagggga ucauuacagu uacugacaug aaaggaaaua acucccauau ccuccugucu      480

gcucugaagu auccugccaa uguggcaguc gauccagugg aaagauuuau auucuggagc      540

uccgaggugg ccggcucacu cuacagggcu gacuuagaug gcgucggggu uaaagcacug      600

cuugagacca gugaaaagau uacagccgug agcuuggacg uacuggauaa gcggcuauuu      660

uggauccagu auaaccgcga gggaucuaau ucccucauuu guucaugcga cuacgauggu      720

ggcagcgugc acaucaguaa acaucccacc cagcacaacc uguucgcuau gucucuuuuu      780

ggggacagaa ucuucuauuc cacuuggaag augaaaacaa uuuggauagc caacaagcac      840

accggaaaag auauggucag gaucaaucug cauagcucgu uugugccuuu gggcgaacuc      900

aagguugugc acccacuggc gcaacccaag gcagaggacg acacguggga accugagcag      960

aaauuaugua agcugcggaa agguaacugc ucauccacug ucugugggca ggaucuccag     1020

ucacaucuuu gcaugugugc cgagggauac gcucugaguc gcgaccgaaa guacugcgaa     1080

gaugugaaug agugugccuu cuggaaccac ggcugcaccu ugggcugcaa aaauacacca     1140

gggagcuauu acuguacuug cccgguagga uucguucuac ugcccgacgg uaagagaugu     1200

caccaacucg uguccugccc uaggaacguc ucugaaugua gccaugauug cgugcugacc     1260

ucagagggcc cacuuuguuu uugccccgaa gggagugucc uggagcggga cggaaaaaca     1320

uguuccggcu gcagcucucc ugauaauggu ggguguucac aguugugcgu gccacucagu     1380

cccguuagcu gggagugcga cuguuucccg ggcuaugauc ugcaguuaga cgaaaagucc     1440

ugcgcagcuu cuggaccuca acccuuucug cuauucgcca acucgcagga uauucgucac     1500

augcauuuug acggcaccga cuacgggacg cuccugagcc agcagauggg aaugguguau     1560

gcgcuugauc acgacccagu agagaauaag aucuacuucg cccauacugc auugaaaugg     1620

auagaacgcg cuaacaugga ugguucccaa agagagaggc ugauugaaga gggcgucgac     1680

gugccugagg ggcucgccgu ugauuggauc ggacggcgau uuuauuggac agaccgcggc     1740

aagucacuga ucgguagaag ugaucuuaau gggaaaaggu cuaagauuau caccaaagaa     1800

aacauuagcc agccccgggg cauagcugug cacccaaugg ccaagcgccu guucuggacu     1860

gacacaggaa ucaaucccag aauugagucc ucuagcuugc agggccucgg gaggcugguc     1920

aucgcaucuu ccgauuuaau cuggccuagu ggaauuacca uagacuuucu gacggauaag     1980

cuauacuggu gugacgccaa acagagcgug aucgaaaugg cuaaccucga ugguucuaag     2040

cgucggcgac ugacccaaaa ugacguaggc cacccauucg cgguggcagu uuuugaggac     2100

uacgucuggu ucuccgauug ggccaugccg ucagugauga gagugaacaa aaggacaggg     2160

aaggaccgcg uccggcuuca gggaaguaug uugaaaccca gcucgcuggu uguggugcau     2220

ccucucgcua agccaggcgc cgaucccugc cuguaucaga acggugggug ugagcacauu     2280

ugcaagaaaa gauuaggcac ugcauggugu uccugcaggg aaggauuuau gaaggccucu     2340

gacggcaaaa ccugucuggc ucuugauggg caucaguugc ucgccggagg cgagguagac     2400

cugaagaauc aagucacacc ucuagauauc cugagcaaaa cucgcguguc agaagacaac     2460

auuaccgaga gucagcacau gcucguugca gaaaucaugg uguccgauca ggacgauugc     2520

gcgccagucg guuguucuau guacgcucga ugcauaagcg agggggagga cgccacaugc     2580

cagugucuga agggauucgc aggcgauggu aaacuuugcu ccgacaucga cgaaugugag     2640

augggcgugc ccguuugccc gccugccuca agcaaaugua uuaauaccga agggggauau     2700

gugugccggu guagugaggg cuaccaaggg gauggaaucc acugcuugga cauugaugaa     2760

ugucagcugg gcgagcauuc uugcggugag aacgcuuccu guacuaauac ggaaggggga     2820

uauacaugca ugugcgccgg ccguuuaagc gagccagguc ucaucugucc cgacucgacc     2880

ccucccccac accugagaga agaugaccau cacuacucag uaaggaacuc ugauagugag     2940

ugcccucuuu cccaugacgg cuauugucug cacgaugggg ucugcaugua cauagaagca     3000

uuggacaagu acgcuuguaa uugcguggug ggauauauug gcgagcgcug ucaguaccgg     3060

gaucucaaau ggugggagcu gagacacgcc gggcauggac aacagcagaa ggucaucguu     3120

guggcgguau gcguggucgu gcuaguuaug cugcuccugc uuagcuugug gggcgcccac     3180

uauuacagga cucagaaacu guuaucuaag aaccccaaaa auccauauga agagagcucc     3240

cgagacgugc gcucacggag accggcugac accgaagaug guaugaguag cuguccucaa     3300

cccugguucg ucgugauuaa ggagcaucag gaccucaaga acgggggaca gccaguugca     3360

ggcgaggaug gucaggccgc ugacggcucu augcaaccca cauccuggag gcaggaaccu     3420

cagcugugcg ggaugggaac cgagcagggc uguuggaucc cagugucaag ugauaaaggg     3480

agcugccccc aagucaugga acguuccuuu cacaugccuu cuuacggaac ucagacacuu     3540

gagggcggug uagaaaagcc gcauucgcug cuaagcgcca auccacucug gcagcaacgc     3600

gcacuggauc ccccucacca gauggaguug acgcagugag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  1704
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt3)

<400>  1704
gggagaaagc uuaccaugac cgccggcaga aggauggaga ugcugugcgc ugggcgggug       60

cccgcacucc uucuguguuu gggauuccac uuacugcagg ccguccuaag cacaacuguu      120

aucccuuccu gcauuccagg ugaaucuuca gacaacugua cggcgcucgu gcaaaccgag      180

gauaauccgc gcguagcuca ggugaguaua acaaagugca gcuccgacau gaacggcuac      240

ugucugcaug ggcagugcau cuaucuuguc gauaugucuc agaauuacug ucgaugcgaa      300

gugggauaua cuggcguucg uugugagcac uuuuuccuga ccgugcauca acccuugucg      360

aaagaauacg ucgcccucac agugauucug aucauucugu uucucaucac cguaguuggu      420

ucaacuuauu acuucugcag augguauagg aaccgcaaga gcaaagagcc uaagaaagag      480

uacgaacggg ugacaagugg ggacccagag uuaccccagg ucugaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  1705
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt3)

<400>  1705
gggagaaagc uuaccauggc cgagggcgaa aucaccacau ucacugcucu gacggagaag       60

uuuaaccuuc ccccugggaa uuacaaaaag ccaaaacucc uguauugcag caacggaggu      120

cacuucuuga gaauuuuacc ggacggcacc guggauggga caagggaccg guccgaucag      180

cauauacaac ugcagcuauc ugcagaauca gucggagagg uuuacaucaa gaguacugaa      240

accggccagu aucucgccau ggacacagau ggucugcuuu acgggagcca gacccccaau      300

gaggaguguc uguuuuugga acgccucgag gaaaaccacu auaauacuua cauuuccaaa      360

aagcaugcgg agaagaacug guucguggga cugaaaaaga auggcucuug caaacgaggc      420

ccucguacac acuaugggca aaaggcuauc cuguuucucc cauuacccgu aucgucagac      480

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  1706
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt3)

<400>  1706
gggagaaagc uuaccauggu gggcgucggg ggaggugacg uugaggaugu gacccccaga       60

ccuggcgggu gccagaucag cggaaggggc gcccgggguu guaacgggau uccaggagcu      120

gcagccuggg aagcggcucu gccgcgccga cgucccagaa ggcacccuuc cguaaaucca      180

cggucucgcg ccgcaggcuc acccagaaca aggggccggc gcacugagga acgaccuagu      240

gggagcagac ucggagacag gggucggggc cgugcccuuc cagggggacg ccugggcggu      300

agagggaggg gacgggcucc cgagcgagug ggcggccgcg ggagaggaag ggguacggca      360

gccccucggg cugccccagc ggcacgcggc uccagaccgg ggcccgccgg aaccauggcu      420

gccggcucua uaacaacuuu gccugcauua ccagaagaug gugggucggg cgcuuuuccc      480

ccuggacauu ucaaggaccc aaaaaggcug uacugcaaga acggcggguu cuuucuacgu      540

auccaccccg auggacgggu cgacggugug cgagagaaau cagauccgca uauuaagcuc      600

caacugcagg ccgaggaaag aggcguugug agcaucaaag gggucugugc gaauagguau      660

cuugccauga aggaggacgg acgccuguug gcaaguaagu gcgugaccga ugaauguuuc      720

uuuuucgagc ggcucgaguc caacaauuac aacacauaua gaucuaggaa auacaccagc      780

ugguauguag cucugaagcg cacuggccag uacaaacugg guuccaagac agggccuggc      840

cagaaagcca uucucuuuuu acccauguca gcuaagaguu gaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  1707
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt3)

<400>  1707
gggagaaagc uuaccaugca caaguggauc cugaccugga uucuccccac acuucuguac       60

agaagcugcu uccauauaau cuguuuggug ggcacuauuu ccuuagccug caacgacaug      120

acgccugagc agauggcuac caaugucaac uguucuucac cagaaaggca cacacggagu      180

uaugauuaca uggagggagg agacauccgc guucgacguc uguuuugcag aacucaaugg      240

uaucuaagga uugauaaacg ggguaaggug aaaggcaccc aggaaaugaa gaauaacuac      300

aauaucaugg agauacgcac aguagcagug gggaucgucg ccauuaaagg aguggaaagc      360

gaguucuauc ucgcgaugaa caaggagggc aagcuguacg cuaaaaagga auguaaugag      420

gacugcaacu uuaaagaacu uauccuggag aaucauuaua acaccuacgc cuccgcaaag      480

uggacucaca auggugggga gauguucguu gccuugaacc agaaagggau uccggugaga      540

ggcaagaaga ccaaaaagga acagaaaaca gcucauuuuc uccccauggc aaucacguga      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  1708
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt3)

<400>  1708
gggagaaagc uuaccaugaa gcugcucccc agcguggucc uuaaacuguu cuuggccgcu       60

guuuuauccg cacuggugac cggcgagucu cuagaaagac ucaggcgggg gcuggccgcg      120

ggaacaucaa acccugaccc accgacugua aguacggauc agcuucugcc cuuggguggc      180

gggcgcgacc gaaaggugcg ugaucuccaa gaggcugacc uggaucugcu cagagucacc      240

uuaagcucca aaccucaggc ccuggcaaca ccaaauaagg aggaacacgg aaaaaggaag      300

aagaaaggca agggucuugg gaaaaagcgg gaccccugcu ugcgcaaaua caaggauuuu      360

uguauccaug gagaaugcaa guaugugaaa gagcugagag ccccuucuug uauuugccac      420

ccaggcuacc auggcgagag gugucacggg cuaucgcucc ccguugaaaa ccggcuguau      480

acuuacgacc auaccacaau acuugcugug gucgcagugg uacugucaag cguuugcuug      540

cucgugaucg ucggacuguu aauguuccgc uaucaccgaa gagguggcua cgauguggag      600

aaugaagaga aggugaaacu ggggaugacc aacagucacu gaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  1709
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt3)

<400>  1709
gggagaaagc uuaccaugug ggugaccaag cugcuccccg cccuucuguu gcagcacguc       60

uuacugcauc uacuccugcu uccuaucgcu auuccauacg cagagggcca aagaaaaagg      120

cggaacacaa uacacgaguu caagaaaagc gccaagacua cgcugaucaa aauugacccg      180

gcguugaaga ucaagaccaa aaagguuaau acagcugauc agugcgccaa ccgcuguacu      240

cgaaauaaag ggcuccccuu uaccugcaag gcauucgugu uugacaaagc ccguaagcag      300

ugucuguggu ucccuuuuaa cuccaugucu ucaggaguaa agaaagaguu cggucaugaa      360

uuugaucugu augagaauaa ggacuacauu agaaacugca ucauaggcaa agggaggagu      420

uauaagggaa cagugagcau caccaaaucc ggcauuaagu gucagccaug gucuucgaug      480

aucccccacg aacauucauu ccucccuagc aguuaccggg guaaagauuu acaagagaau      540

uauugccgca acccaagagg ggaggaagga ggccccuggu guuuuacuuc caauccugag      600

gucagguacg aagugugcga cauuccacag uguucugagg uugagugcau gacauguaac      660

ggcgaaagcu aucgggggcu gauggaucac accgaguccg gaaagaucug ccagcgcugg      720

gaccaccaga cgccgcaucg acacaaguuc cuucccgaaa gauacccuga uaaagguuuu      780

gacgauaauu acugcaggaa cccagacggc caaccccggc cuugguguua uacuuuggau      840

ccacauaccc guugggaaua cugcgcuaua aagacaugug cagacaauac uaugaacgac      900

accgaugugc cccuggaaac aaccgagugc auucaggggc agggagaggg cuaucgcggu      960

acggucaaua cuaucuggaa cgggauuccg ugucagagau gggacucaca auacccucac     1020

gaacacgaua ugacacccga gaacuucaaa ugcaaggacc uaagggaaaa uuauugucgg     1080

aacccagaug gaagugagag cccuuggugc uuuaccacug accccaauau ccgagugggc     1140

uacuguucuc agaucccaaa cugcgauaug ucccauggcc aggacuguua ucgcgggaau     1200

gguaaaaacu acaugggaaa ucucucacaa acaagaagcg gccugaccug caguaugugg     1260

gauaagaaca uggaagaccu ucacaggcau auuuucuggg agcccgaugc cucuaagcug     1320

aaugagaacu acugccggaa uccugacgac gaugcucacg ggccauggug uuauacggga     1380

aacccguuga uacccuggga cuacugcccu aucucccgcu gugaaggcga uaccacacca     1440

acuauuguaa aucucgacca ucccguuauc agcugcgcca aaaccaagca gcugagagug     1500

gucaacggua uaccuacaag gacuaauauu ggguggaugg ugucguuacg uuaucggaac     1560

aaacacaucu guggcggauc ucugaucaag gaguccuggg ugcucaccgc gcgacagugc     1620

uucccaucaa gagaucuuaa agacuacgaa gcauggcugg gcauucacga uguccauggg     1680

aggggagacg agaaguguaa gcagguuuug aacgugaguc agcuaguaua uggucccgaa     1740

ggcagcgauc uggugcucau gaaacuggcc cgcccggcug uccuugacga uuuugugucc     1800

acaaucgacc ugccuaauua cgggugcacc auuccagaga agacuucuug uagcguuuau     1860

ggauggggcu acacggguuu gauaaacuac gaugggcucc ugcggguggc ccacuuauau     1920

aucaugggca augagaaaug cucacaacau cacagaggaa aggucacacu gaacgaaagu     1980

gagauuugug caggcgcuga gaaaaucggg uccggacccu gcgaagguga cuacggcggg     2040

ccucuagugu gcgagcagca caagaugagg augguacucg gaguuaucgu gcccggccgc     2100

gguugugcca uuccaaaucg accugggaua uucguccggg uggcguauua cgccaagugg     2160

auccauaaaa uuauccugac cuauaagguc ccccagagcu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  1710
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt3)

<400>  1710
gggagaaagc uuaccauggc caaggcugca gccaucggca uugaccuggg gaccacauac       60

agcugcgugg gagucuucca gcacgguaaa guugagauaa ucgcgaacga ucaaggcaau      120

agaacuacgc ccuccuaugu ggcuuuuacc gacacagaaa ggcucauugg ggaugccgca      180

aagaaccagg uagcccuuaa uccucagaac acuguguucg acgcuaaacg gcugaucgga      240

cgcaaguuug gcgauccagu cgugcagucu gacaugaaac auuggccguu ccaaguuauu      300

aaugauggug acaagcccaa ggugcagguc ucauacaaag gggagaccaa ggcauuuuau      360

ccugaagaga ucaguagcau gguguugaca aaaaugaagg aaauagccga ggcuuacuua      420

ggauauccag uaaccaacgc cguuaucacu gugcccgcgu acuucaauga uucccagcga      480

caggcaacaa aagacgccgg cgucauugcu ggccugaacg ugcuacguau cauuaaugag      540

ccuaccgccg cagcuaucgc cuaugggcuc gauagaacgg gaaaggguga aaggaacgug      600

cugauauuug accuuggcgg gggaacuuuc gaugucucua uucugaccau cgacgacggc      660

auuuuugagg uuaaggcgac agccggugau acucaccuug ggggagaaga cuucgauaau      720

cggcucguga accauuuugu agaggaguuc aaacgcaagc acaaaaagga caucucgcaa      780

aauaaaagag cagugaggcg gcugcgcacc gcuugugaac gagccaagag aacacuguca      840

agcaguaccc aggcuucccu cgagaucgau ucuuuauuug aaggcauuga cuucuacacg      900

agcauaacua gggcccgguu cgaggaacug ugcuccgauc uuuuucguuc aacauuggag      960

ccagucgaga aagcacugcg cgacgccaag cuagauaagg cucagaucca ugaccucgug     1020

cugguuggcg ggaguacccg gauucccaaa gugcagaagu ugcugcaaga uuucuuuaac     1080

ggaagggacu ugaauaaaag caucaacccu gacgaagcgg ucgcauacgg ugccgcugug     1140

caggccgcaa uacucauggg cgauaagucu gagaacguac aggaccuguu acugcucgau     1200

guugccccac uuucccuggg guuggaaacu gcuggaggcg ugaugacagc ccuaauuaaa     1260

agaaauucaa ccaucccgac gaagcaaacc cagaucuuca caacuuauag cgacaaccag     1320

cccggugucc ugauucaggu guacgagggg gaacgagcaa ugaccaagga uaauaaccuc     1380

cugggccgcu uugagcuuag uggaaucccu ccagcgccca gaggcguccc ucaaauugag     1440

gugacauucg acauagaugc uaaugggauc cugaacguua cugccaccga caaaucuaca     1500

ggaaaggcaa auaaaauuac caucacuaac gauaagggua gguuguccaa agaagagauc     1560

gaacggaugg ugcaggaggc cgaaaaguau aaggcugagg acgagguaca gcgcgaaaga     1620

gucagcgcca aaaaugcacu cgagucguac gcuuuuaaca ugaagucugc cguggaagau     1680

gagggccuga aagggaagau uuccgaggcg gacaaaaaga agguuuuaga uaaaugucag     1740

gaagugauau cauggcugga cgccaauacg cuagcugaga aggacgaguu cgaacacaaa     1800

aggaaggaac ucgagcaagu cugcaaccca aucauuagug gacuguauca gggcgccggu     1860

gggcccggcc cgggaggcuu uggggcacag ggaccuaaag guggcagcgg guccggaccc     1920

acaaucgagg aaguggauug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1711
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt3)

<400>  1711
gggagaaagc uuaccauggc caaggcugca gccaucggca uugaccuggg gaccacauac       60

agcugcgugg gagucuucca gcacgguaaa guugagauaa ucgcgaacga ucaaggcaau      120

agaacuacgc ccuccuaugu ggcuuuuacc gacacagaaa ggcucauugg ggaugccgca      180

aagaaccagg uagcccuuaa uccucagaac acuguguucg acgcuaaacg gcugaucgga      240

cgcaaguuug gcgauccagu cgugcagucu gacaugaaac auuggccguu ccaaguuauu      300

aaugauggug acaagcccaa ggugcagguc ucauacaaag gggagaccaa ggcauuuuau      360

ccugaagaga ucaguagcau gguguugaca aaaaugaagg aaauagccga ggcuuacuua      420

ggauauccag uaaccaacgc cguuaucacu gugcccgcgu acuucaauga uucccagcga      480

caggcaacaa aagacgccgg cgucauugcu ggccugaacg ugcuacguau cauuaaugag      540

ccuaccgccg cagcuaucgc cuaugggcuc gauagaacgg gaaaggguga aaggaacgug      600

cugauauuug accuuggcgg gggaacuuuc gaugucucua uucugaccau cgacgacggc      660

auuuuugagg uuaaggcgac agccggugau acucaccuug ggggagaaga cuucgauaau      720

cggcucguga accauuuugu agaggaguuc aaacgcaagc acaaaaagga caucucgcaa      780

aauaaaagag cagugaggcg gcugcgcacc gcuugugaac gagccaagag aacacuguca      840

agcaguaccc aggcuucccu cgagaucgau ucuuuauuug aaggcauuga cuucuacacg      900

agcauaacua gggcccgguu cgaggaacug ugcuccgauc uuuuucguuc aacauuggag      960

ccagucgaga aagcacugcg cgacgccaag cuagauaagg cucagaucca ugaccucgug     1020

cugguuggcg ggaguacccg gauucccaaa gugcagaagu ugcugcaaga uuucuuuaac     1080

ggaagggacu ugaauaaaag caucaacccu gacgaagcgg ucgcauacgg ugccgcugug     1140

caggccgcaa uacucauggg cgauaagucu gagaacguac aggaccuguu acugcucgau     1200

guugccccac uuucccuggg guuggaaacu gcuggaggcg ugaugacagc ccuaauuaaa     1260

agaaauucaa ccaucccgac gaagcaaacc cagaucuuca caacuuauag cgacaaccag     1320

cccggugucc ugauucaggu guacgagggg gaacgagcaa ugaccaagga uaauaaccuc     1380

cugggccgcu uugagcuuag uggaaucccu ccagcgccca gaggcguccc ucaaauugag     1440

gugacauucg acauagaugc uaaugggauc cugaacguua cugccaccga caaaucuaca     1500

ggaaaggcaa auaaaauuac caucacuaac gauaagggua gguuguccaa agaagagauc     1560

gaacggaugg ugcaggaggc cgaaaaguau aaggcugagg acgagguaca gcgcgaaaga     1620

gucagcgcca aaaaugcacu cgagucguac gcuuuuaaca ugaagucugc cguggaagau     1680

gagggccuga aagggaagau uuccgaggcg gacaaaaaga agguuuuaga uaaaugucag     1740

gaagugauau cauggcugga cgccaauacg cuagcugaga aggacgaguu cgaacacaaa     1800

aggaaggaac ucgagcaagu cugcaaccca aucauuagug gacuguauca gggcgccggu     1860

gggcccggcc cgggaggcuu uggggcacag ggaccuaaag guggcagcgg guccggaccc     1920

acaaucgagg aaguggauug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1712
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt3)

<400>  1712
gggagaaagc uuaccauggc caccgcuaag ggcaucgcaa uugggauaga ccugggaaca       60

acuuacagcu gcgugggugu cuuccagcac ggcaaaguug agaucauugc caacgaucaa      120

gggaauagaa cgacccccuc cuauguggcg uuuacagaca cugaaaggcu caucggagau      180

gcugccaaga accagguagc aaugaauccu cagaacaccg uguucgacgc caaacggcuu      240

auuggccgca aguuuaauga uccagucgug caggcugaca ugaaacugug gccguuccaa      300

guuaucaacg agggugggaa gcccaaggug uuggucucuu acaaaggaga aaauaaggca      360

uuuuauccug aggaaauauc aaguauggug uuaacaaaac ugaaggagac cgccgaggcu      420

uuccuaggcc auccaguaac uaacgccguu aucacagugc ccgcguacuu uaaugauagc      480

cagcgacagg caaccaaaga cgccggcguc auugcugggc ucaacgugcu gcguaucauu      540

aaugaaccua cggccgcagc uaucgccuau ggacuugaua aggguggcca gggggagaga      600

cacgugcuga uauucgacuu gggaggcggu acuuuugaug ucuccauucu caccaucgac      660

gaugggauuu ucgaaguuaa ggcgacagcc ggagacacuc aucugggcgg cgaggacuuu      720

gauaacaggc uggugucuca cuucguagag gaauuuaaac ggaagcauaa aaaggacauc      780

ucgcaaaaua aacgcgcagu gagaaggcuc cggaccgcuu gugagcgcgc caagcgaaca      840

uuaucaagca guacccaggc uaaccuggaa aucgauuccc uuuacgaggg gauugacuuc      900

uauacgucua uaacuagagc cagguucgaa gaguugugcg cagaucuguu ucggggaaca      960

cuagagccag ucgaaaaagc ccuccgugac gcuaagaugg auaaggcgaa aauccacgac     1020

auugugcugg uugguggcag cacccgcauc cccaaggugc agagacuucu gcaggauuac     1080

uucaauggga gggacuugaa caaauccaua aacccugaug aggcagucgc cuacggagcu     1140

gccgugcaag cagccauucu caugggcgac aagucagaaa aaguacagga ccuguuacug     1200

cucgauguug cuccacuuag ucuggguuug gagacugccg ggggcgugau gacagcacua     1260

aucaagcgga auagcaccau cccgacgaag cagacccaaa uuuuuacaac uuauucugac     1320

aaccagcccg gaguccugau ccagguguac gaaggcgagc gagcgaugac caaagauaau     1380

aaccuccugg ggcgcuucga ccuuacaggg auuccuccag cucccagagg ugucccucag     1440

auagagguga cuuuugauau cgacgccaau ggcauucuga acguuaccgc aacagauaag     1500

uccaccggga aagugaauaa gaucacuauc acgaacgaca aaggaagguu gucaaaggaa     1560

gagauugaac ggaugguacu cgaugccgag aaguauaaag cugaagacga gguccaacgc     1620

gagaagauag ccgcuaaaaa ugcacuggaa agcuacgccu ucaacaugaa gagugugguu     1680

ucugaugagg gcuuaaaagg uaagaucucc gaaagcgaca agaauaaaau ucuggauaag     1740

uguaacgagc uacucucgug gcuggaggug aaucagcuug cggaaaaaga cgaguuugac     1800

cacaagagaa aagaauugga gcagaugugc aacccaauca uuacaaagcu guaucaggga     1860

ggcuguaccg gacccgccug cggcacuggg uacgucccgg gaaggccugc uaccgguccc     1920

acaaucgaag agguggauug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1713
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt3)

<400>  1713
gggagaaagc uuaccaugag cgccagaggc cccgcuaucg ggauugaccu gggaaccaca       60

uacuccugcg ugggugucuu ccagcacggc aagguugaga uaaucgcaaa cgaucaaggg      120

aauaggacua cgccuucuua uguggccuuu accgacacag aacggcucau uggagaugcg      180

gcuaaaaacc agguagccau gaauccaacu aacaccaucu ucgacgcaaa gcgccuuauu      240

ggccgaaaau uugaggaugc cacagugcag ucagacauga agcauuggcc guuccguguc      300

gugagugaag gugggaaacc caagguucag guggaguaca agggagaaac caaaacauuu      360

uucccugagg agaucagcuc caugguccug acuaagauga aagaaauagc ugaggcauau      420

uugggcggca aggugcacuc ugccguaauc accguuccag cuuacuuuaa ugauucgcaa      480

agacaggcca cgaaagacgc ggggacuauu accggauuaa acgugcugag gaucauuaau      540

gaacccacag cagccgcuau cgccuauggu cuagauaaga agggcugugc agggggagag      600

aaaaacgucc ucauauucga ccugggcggu gggacuuuug augugucaau ucuuaccauc      660

gaggacggaa uuuucgaagu caagagcaca gcuggcgaua cccaucuggg cggggaggac      720

uuugacaauc ggauggugag ucacuuggcc gaagaguuca aacgcaagca uaaaaaggau      780

aucggaccua acaaaagagc gguuaggcgg cuccgcacgg ccugcgaacg agcaaagaga      840

acucuguccu cuagcacaca ggcuuccauc gagauugacu cacuguacga ggguguggau      900

uuuuauacca guauaacuag ggcccgguuc gaggaacuca augcugacuu auuccguggc      960

acacuggaac caguagagaa ggcccuucgc gaugcaaaau uggacaaggg gcagauccaa     1020

gaaauugugc uggucggagg cagcaccaga auccccaaaa uacagaagcu acuccaggac     1080

uuuuucaacg guaaagagcu gaauaagucu auuaacccug augaggccgu ggcuuacggg     1140

gcggcaguuc aggccgcuau ccuuaucggc gauaaguccg aaaaugugca agaccuguug     1200

cuccuggaug ucacgccauu aucacuggga auugagaccg ccggcggggu gaugacaccg     1260

cucaucaaaa ggaacacuac cauucccaca aagcagacuc agaccuuuac aaccuacagc     1320

gacaaccaaa guucuguacu uguucaggug uaugaaggag agcgggcaau gacuaaagac     1380

aauaaccugu uggguaaguu cgaucuaacg ggcauaccuc cagcuccccg aggggucccu     1440

cagaucgaag ugacauuuga cauugaugcc aauggaaucc ugaacgucac cgccgcagac     1500

aaauccacug gcaaggagaa uaagaucacc auuacaaacg auaaaggucg ccucagcaag     1560

gacgauauag acagaauggu gcaggaggcg gaaagguaca aaucggagga ugaagcuaau     1620

cgggaccgcg uugccgcaaa gaacgcccug gagucuuaua ccuacaauau caaacaaacu     1680

guggaggaug aaaaacuuag agggaagauu uccgagcagg acaagaacaa gauccuggau     1740

aaaugucagg aaguaauuaa uugguuggac aggaaccaga uggcugagaa ggacgaauau     1800

gagcacaaac aaaaggagcu cgaacguguc ugcaauccaa ucauaucaaa acuguaccag     1860

ggcggacccg gcgggggaag ugguggcggg ggaagcggcg ccuccggugg gccgacaauc     1920

gaggaagugg auugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  1714
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt3)

<400>  1714
gggagaaagc uuaccaugag cguggucggc aucgaccugg gguuccaguc cugcuacguu       60

gccguggcua gagcaggagg uauugagacc auagccaacg aauauucuga uagguguaca      120

cccgcgugca ucucauuugg cccuaagaau cggaguauug gggcugccgc aaaaagccaa      180

guaaucucca acgccaagaa uacugugcag ggauucaaac gcuuucacgg ccgagcuuuc      240

ucugacccau uugucgaggc agaaaagucg aaccucgccu acgauauugu gcagcuuccg      300

acgggucuga ccgggaucaa aguuacauau auggaggaag aacguaauuu cacuaccgaa      360

caggugacag cuauguuguu aucaaagcug aaggaaaccg ccgagagcgu ccucaaaaag      420

cccgugguag acuguguugu gagugucccu ugcuuuuaca cugaugcgga aagaaggucc      480

gugauggacg caacacaaau agccggacua aacugucugc ggcuuaugaa ugagaccacg      540

gcuguggccc uggcauaugg caucuacaaa caggauuugc cagcucucga ggaaaagccc      600

cgcaacgucg uuuucgugga caugggccau ucugccuauc agguaagcgu gugcgcguuu      660

aauagaggga aacugaaggu ccuggccacu gcauucgaua ccacacucgg agguaggaag      720

uuugacgagg uguuaguuaa ccacuucugu gaagaguuug gcaaaaagua caaacuggau      780

auuaagucca aaauccgggc ucuuuugcgc cugucacagg aaugcgagaa gcucaaaaag      840

cuaaugagug ccaaugcuag cgaccugccu cuuucuauug aguguuucau gaacgaugug      900

gacgucuccg ggacuaugaa ucgaggaaag uuccuggaaa ugugcaacga cuugcucgcc      960

agaguggagc caccccugag gucaguauua gaacaaacca aacugaagaa agaggauauc     1020

uacgcaguug aaauaguggg cggugccaca cggauuccug cugucaagga gaaaaucagc     1080

aaguuuuucg ggaaggagcu caguaccacg cuuaaugcgg acgaagcagu gacucgugga     1140

ugugcccugc agugcgcuau uuugucucca gccuuuaaag uccgcgaguu cuccaucaca     1200

gaugugguuc cguaucccau cagccuaaga uggaacucgc cugcagaaga ggggucuucc     1260

gacugcgaag uguuuucaaa gaaccaugcc gcuccauuca guaaaguacu gaccuuuuac     1320

aggaaggagc ccuucacucu cgaggccuau uacagcuccc cucaggaucu gccauauccc     1380

gacccggcaa uugcgcaguu uucuguccaa aaagugacac cucagagcga uggcucaagu     1440

uccaagguua aggugaaagu ccgggugaau guacacggca uauucagcgu gucuucagcu     1500

agucuuguug aaguccauaa gagcgaggaa aacgaggagc ccauggaaac cgaccagaau     1560

gccaaagagg aagagaagau gcaaguggau caggaggagc cacacgugga ggaacagcag     1620

caacagacgc cugcagagaa caaagccgaa uccgaggaaa uggagaccuc ucaggcugga     1680

ucgaaggaca agaaaaugga ucagccccca caagccaaga aagcaaaggu caaaacaagc     1740

acuguugacc ugcccaucga gaaucaguug cucuggcaga uugaccgaga aaugcugaac     1800

uuauacaucg agaaugaagg uaagaugaua augcaggaua aacuggagaa ggaacgcaac     1860

gacgcuaaga augccgugga ggaguaugug uacgaaauga gagauaaacu auccggcgag     1920

uacgaaaagu uuguaucaga ggacgauagg aacaguuuca cccucaaacu ggaggacaca     1980

gaaaauuggc uuuaugagga uggggaagac caaccuaagc aggucuacgu ggauaaauug     2040

gcggagcuga agaaccucgg acagccaauu aagauccggu uucaggaauc ugaggagcgc     2100

ccgaaacugu ucgaggagcu uggcaagcaa auccagcagu auaugaaaau uaucagcucc     2160

uucaagaaua aagaagacca auacgaucac cuggacgccg cugauaugac uaagguugag     2220

aagucaacca acgaagcaau ggaguggaug aauaacaaau ugaaccucca gaauaagcag     2280

agccugacaa uggaccccgu ggucaaaucu aaggagauug aagccaaaau aaaggaguua     2340

accuccacuu guaguccuau cauuagcaag ccaaaaccca agguggaacc uccaaaagag     2400

gaacagaaga acgcugagca aaaugguccc guugacgggc agggcgauaa cccgggaccu     2460

caggccgcag agcagggcac ggacacagcg gugccaucug auuccgacaa aaagcugccc     2520

gaaauggaua ucgacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  1715
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt3)

<400>  1715
gggagaaagc uuaccaugag cguggucggc aucgaccugg gguuccucaa cugcuacauu       60

gccguugcua gauccggagg uauagagacc aucgcaaaug aauauucuga uagguguaca      120

cccgccugca uuucacuugg cagucggacu cgcgcgaucg ggaacgcugc caagagccag      180

auugugacga auguacgaaa caccauccac ggauuuaaaa agcugcaugg ccguuccuuc      240

gacgauccua uagugcaaac agagagaauc agguugccau acgaauuaca gaaaaugccg      300

aaugguucug caggggucaa ggugcgguau cuggaggaag agagacccuu ugccauugag      360

cagguuacug gaaugcuacu cgcuaaacug aaggaaaccu cggagaacgc acuuaagaaa      420

ccuguggccg acugugucau cucaauuccc agcuucuuua cagaugcuga aagaaggagu      480

gugauggccg cggcacaggu agccggccug aauugcuugc ggcucaugaa cgagaccacu      540

gcuguugccc uggcauacgg caucuauaag caagaccugc caccucucga ugagaaacca      600

cgcaaugugg ucuucauaga cauggggcac uccgcuuacc agguguuagu gugugccuuu      660

aacaagggaa aacugaaggu ccuugcgaca accuucgauc ccuauuuggg uggccgaaau      720

uuugacgaag cccugguuga uuacuucugc gacgaguuua agacgaaaua caagauuaac      780

gugaaagaaa auucuagagc acuacucagg cuguaucagg agugugaaaa acuuaagaag      840

cugaugagcg cuaacgccuc cgauuugccu cucaauaucg agugcuucau gaacgaccug      900

gacguaucaa guaaaaugaa ccgggcucag uuugagcaau uaugugccag ccugcucgca      960

cguguggaac caccgcuuaa ggccgucaug gagcaggcua aucugcagcg cgaagauauu     1020

ucuuccaucg agaucguugg gggagcgacu cgcauucccg cagugaagga acagauaacc     1080

aaauucuucu ugaaggacau cucaacaacu cuaaacgccg augaggcugu ggccaggggc     1140

ugcgcacugc aaugugccau ucucagcccu gcuuuuaaag uccgggaguu caguaucacc     1200

gaccuggugc cauacucuau aacacuucga uggaagaccu ccuuugaaga ugguagcggg     1260

gagugcgaag uauucugcaa aaaucauccc gccccuuuuu cgaagguuau uacguuccac     1320

aagaaagagc cauuugaacu ggaggcauuc uauacuaacu ugcaugaggu gcccuacccg     1380

gacgcgcgca ucggaucuuu uacaauccag aaugucuucc cucaguccga uggcgacuca     1440

aguaagguga aagucaaggu gagaguuaac auucacggca ucuuuagcgu ggcuuccgcc     1500

ucuguaauug aaaaacaaaa ucucgagggg gaucacagcg acgcacccau ggaaaccgag     1560

acuucauuca agaacgagaa uaaggauaac auggacaaaa ugcaggucga ccaggaagag     1620

ggacaucaga agugucacgc cgaacauaca ccagaggaag agauagauca caccggugcu     1680

aaaacgaaga gugccguguc cgacaaacaa gauaggcuga aucagaccuu aaagaagggc     1740

aaaguuaaga gcaucgaccu gccuauucag ucuucacuau gccggcagcu cgggcaagau     1800

cugcuuaaca guuauaucga gaaugaagga aaaaugauca ugcaggacaa guuggagaaa     1860

gaacgcaacg augcaaagaa ugcuguggag gaauacgucu augacuuuag agauaggcug     1920

ggcacagugu acgagaaauu cauuacuccc gaggaccuca gcaagcuguc cgccguacuu     1980

gaagauaccg agaacuggcu guacgaagac ggugaggauc agccaaaaca gguguauguu     2040

gacaaguugc aagaacucaa gaaauacggg cagcccauac agaugaagua uauggagcac     2100

gaggaacguc cuaaagcgcu gaacgacuua ggcaagaaga uccagcuggu caugaaagug     2160

auugaggccu accggaauaa ggaugaacga uaugaccauc uagauccaac agagauggag     2220

aaaguggaaa aguguaucuc ugacgcuaug ucguggcuca acagcaaaau gaaugcacaa     2280

aacaagcugu cccuuacuca ggauccgguc guuaaggugu cagagauugu ggccaaaagu     2340

aaggaauugg acaauuucug caaccccauc auauacaaac cuaagccaaa agcugaggua     2400

cccgaagaua agccuaaggc caauucugag cacaacggac caauggacgg ccagagcggg     2460

accgagacaa aauccgauuc aaccaaggac agcucucaac auacuaaauc caguggagaa     2520

auggaggucg auugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  1716
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt3)

<400>  1716
gggagaaagc uuaccaugaa gcugagccuc guggccgcua ugcuucuguu guuauccgca       60

gccagagcgg aggaagagga caaaaaggaa gaugucggca ccguuguggg gaucgaccug      120

ggaacaacuu acucuugcgu agguguguuc aaaaacggca gggucgagau uauagcuaau      180

gaucagggga accggaucac gcccucauau guggccuuua ccccugaagg agagcgccua      240

auuggcgacg cagccaagaa ucaacucaca aguaacccag agaauacugu uuucgaugcu      300

aaacgacuga ucggucguac cuggaacgac ccgagcgugc agcaggauau uaaguuucuu      360

cccuucaagg ucguggaaaa gaagacaaaa ccuuacaucc agguagacau agggggaggc      420

caaaccaaga cuuuugcacc agaggaaauc uccgccaugg uucugacaaa aaugaaggag      480

accgcugagg ccuauuuggg caagaaagug acgcacgcgg ucgugacugu gcccgcauac      540

uucaaugaug cccagagaca ggcuaccaag gacgccggga caauugcagg acucaacguc      600

augaggauca uuaaugaacc uacugcugcc gcgaucgccu auggucugga uaaacgggag      660

ggcgaaaaga acauacuggu uuuugaccuc gggggaggca ccuucgaugu gucuuuacug      720

acaauugaca augguguauu ugaggugguc gcaaccaacg gggacacgca ucuuggaggc      780

gaagauuucg accagcgcgu gauggagcac uuuaucaaau uguacaagaa aaagacuggc      840

aaggauguua gaaaagacaa uagggcugug caaaagcugc ggcgcgaggu cgaaaaagcc      900

aagcgagcuc uaucgucaca gcaucaggcc agaauugaga ucgaaucuuu cuaugagggg      960

gaagauuuua gugagacacu caccagggca aaauucgagg aacugaacau ggaccuuuuc     1020

cgguccacua ugaagccagu gcagaaggua cuggaggauu cugacuugaa aaagagcgau     1080

aucgacgaaa uuguucucgu gggagguucc acacguauac ccaaaaucca acagcugguc     1140

aaggaguuuu ucaauggcaa agaaccuuca cgcgggauua acccagauga ggccguggcu     1200

uacggagcgg caguccaggc cggcguguua aguggugacc aagacaccgg ggaucugguu     1260

cuccuugacg uguguccgcu gacguugggc aucgagaccg uaggaggcgu caugacaaag     1320

cuaauaccca gaaacacugu gguuccuacc aagaaaagcc agauuuuuag cacagcuucc     1380

gauaaucagc caacugugac caucaagguc uacgaagggg agaggccccu gacaaaagac     1440

aaccaccucc ugggaaccuu cgaucuuacu gguaucccuc cagcaccccg gggcgugccg     1500

cagauugaag uaacguuuga gaucgacgug aaugggauuc ugcgaguuac agccgaggau     1560

aagggaaccg gcaacaaaaa uaagauaacu aucaccaacg accaaaaucg cuugacaccu     1620

gaagagauug aaagaauggu caacgaugcc gagaaguucg cugaagagga caaaaagcuc     1680

aaagagagga ucgauacccg gaaugaacug gagucauaug ccuacagcuu aaagaaccag     1740

aucggugaca aagaaaagcu agggggcaaa cugaguucug aggauaagga aacuauggag     1800

aaggcagugg aggagaaaau ugaauggcuc gaaucccauc aggacgcgga cauagaggau     1860

uuuaaggcua aaaagaaaga acuggaggag aucgugcagc ccauuaucag caaacuuuau     1920

ggaucggccg gcccaccucc cacaggggaa gaggacacgg cagaaaagga ugaguuguga     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  1717
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt3)

<400>  1717
gggagaaagc uuaccaugca ggcccccaga gagcuggcug ugggcaucga ccucgggacc       60

acauacagcu gcgucggagu uuuccaacag gguagggugg aaauucuugc aaacgaucag      120

ggcaaucgga cuacgccuuc cuauguagcc uuuaccgaca cagagcgccu ggugggggau      180

gcggcuaagu cucaggccgc auugaaccca cacaauacug ucuucgacgc caaacgauua      240

auaggacgua aguuugcuga uaccacagug caaucagaca ugaaacauug gccguucaga      300

guugugagug aaggcgguaa gcccaaaguc aggguguguu accgcgggga ggauaagacc      360

uuuuauccug aagagaucag cuccauggua cugucuaaga ugaaagagac ugcagaagcc      420

uaccuaggac agccaguuaa gcacgcugug auuacagucc ccgccuauuu caacgacucg      480

cagcggcagg cgaccaaaga ugcaggcgcc aucgcuggcc ucaaugugcu gagaauuauc      540

aacgagccua cggccgcagc uauagccuac gggcuugaca ggcggggagc gggugaacgc      600

aaugugcuga ucuuugauuu gggcggggga acuuucgacg ucucaguucu cagcauugau      660

gccggcgugu uugagguaaa ggcaaccgcu ggugacacac aucucggggg agaggacuuc      720

gauaaccgac uggugaauca cuuuauggaa gaguucagaa ggaaacaugg caaggaccug      780

aguggcaaca agcgggccuu acgucgccug agaacugcuu gcgaaagggc caaacggacc      840

cuuuccucua gcacacaagc aaccuuggag aucgauuccc uguuugaagg ggucgacuuc      900

uauacgucaa uuacucgagc ccgcuucgag gagcuaugua gugaucucuu uagaagcaca      960

cuggaaccag uggagaaggc ucuuagggac gcgaaacugg auaaggcaca gauccacgac     1020

guuguguugg ucggagguuc uacccggaua cccaaagugc agaagcuccu gcaggauuuc     1080

uuuaauggca aagaauuaaa caaguccauu aauccugacg aggccguagc uuacggggcc     1140

gcaguucaag ccgcugugcu gaugggagau aagugcgaaa aaguccagga ccuccuucug     1200

uuggacgugg ccccacuauc acugggccuc gagacugccg guggggucau gacaacccug     1260

auccagcgca acgcgacgau uccgaccaag caaacacaga cuuucaccac auacagcgau     1320

aaucagcccg gcguguuuau ccagguuuau gagggagaaa gagcuaugac uaaagacaac     1380

aaccuucugg gcagguucga guugaguggg aucccuccag caccccgugg agugccucaa     1440

auugaaguaa ccuuugauau agacgcaaau gguauccucu cugucacagc caccgaucgg     1500

uccacuggca aggcuaacaa aauuacgauc acaaaugaca aggggcgacu gagcaaggag     1560

gaaguggaga gaaugguuca cgaggccgaa caguacaaag cagaggauga agcucagagg     1620

gaccgcgugg ccgcgaagaa cucguuagag gcccaugucu uccacgugaa aggaucucug     1680

caggaggaau cccuacggga uaagauacca gaggaagaca gaaggaaaau gcaagauaag     1740

ugucgcgagg uacucgcuug gcuggaacau aaucagcuug cagagaagga ggaauaugag     1800

caccagaaac gagaauugga gcagauuugc cggcccaucu uuucacgucu guacggcggu     1860

ccgggggugc cuggcggaag uagcuguggc acccaagcca gacaggggga ccccuccacu     1920

ggaccaauca uugaagaggu ugauugagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  1718
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt3)

<400>  1718
gggagaaagc uuaccaugca ggcccccaga gagcuggcug ugggcaucga ccucgggacc       60

acauacagcu gcgucggagu uuuccaacag gguagggugg aaauucuugc aaacgaucag      120

ggcaaucgga cuacgccuuc cuauguagcc uuuaccgaca cagagcgccu ggugggggau      180

gcggcuaagu cucaggccgc auugaaccca cacaauacug ucuucgacgc caaacgauua      240

auaggacgua aguuugcuga uaccacagug caaucagaca ugaaacauug gccguuccag      300

guugugagug aaggcgguaa gcccaaaguc agaguguguu acaggggaga ggauaagacc      360

uuuuauccug aagagaucag cuccauggua cugucuaaga ugaaagagac ugcagaagcc      420

uaccuagggc agccaguuaa gcacgcugug auuacagucc ccaccuauuu cucgaacuca      480

cagcggcaag ccacgaaaga cgcgggcgca aucgccggcc ucaaggugcu gccuauuauc      540

aaugaggcua cugccgcagc uauagccuac gggcuugauc gcagaggagc ggguaaaagg      600

aacgugcuga ucuuugacuu gggcggggga accuucgaug ucagcguucu caguauugac      660

gccggcgugu uugaaguaaa ggcaacagcu ggugauacuc aucuuggggg agaggacuuc      720

gacaaucggc uggugaacca cuuuauggag gaguuccgcc gaaagcaugg caaagaucuc      780

uccggcaaua agagagccuu aaggcggcug cguaccgcuu gcgagcgcgc caaaagaaca      840

ccaucuagcu ccacccaggc aacgcuugaa aucgacucau uguuugaggg ggucgauuuc      900

uauaagagua uuacuagggc ccgguucgaa gaacugugua gcgaccuauu ucgaucuaca      960

cucgagcccg uggaaaaagc ucugcgcgau gcgaagcugg acaaagcaca gauccacgau     1020

uucguucugg gagguggcuu gcacucccau ccucaggggg ccgagguggc ugccggacuc     1080

cugcaaagac agggcgcaga acaggagcac caaccaugag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  1719
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt3)

<400>  1719
gggagaaagc uuaccaugag caagggcccc gccgugggga ucgaccuggg aaccacauac       60

uccugcgucg guguuuucca gcacggcaaa guggagauua uagcuaacga ucaagggaau      120

agaacuacgc cuucuuaugu agcauuuacc gacacagaaa ggcucaucgg agaugccgcg      180

aagaaccagg uggcuaugaa uccaacuaac accgucuucg acgccaaacg gcuuauuggc      240

cgccgauuug augacgcagu gguucaguca gauaugaagc auuggccguu cauggugguc      300

aaugacgccg gucgucccaa agugcaggua gaguacaagg gggaaacaaa gaguuuuuau      360

ccugaggaag uuagcuccau ggugcugacc aaaaugaagg agaucgcuga ggcauacuug      420

ggaaaaacug ucacaaacgc cguggugacc gucccagcuu auuucaauga uucucaaaga      480

caggccacga aggacgcggg cacuauugca ggcuuaaacg uucugaggau cauaaaugaa      540

cccaccgccg cugccaucgc auacgggcua gauaaaaagg ugggagcuga gcggaacgua      600

cucauuuuug accugggugg cgggacauuc gaugugucga uccuuacuau ugaagacgga      660

aucuuugagg ucaagucaac cgccggcgac acacaccugg guggggagga uuucgacaau      720

cgcaugguga accauuuuau agcggaauuu aaaagaaagc acaaaaagga uauuagcgag      780

aauaaaaggg ccguucggcg cuugcgaacc gcaugugaaa gagcuaagag gacgcucagu      840

uccucuacuc aggccagcau cgagauugac ucccuguaug aaggaaucga uuuuuacaca      900

ucaaucaccc gggcucguuu cgaggagcug aacgccgacc ucuuccgcgg cacuuuagau      960

ccuguggaaa aagcacugag agacgccaaa cuugauaaga gucagauuca ugacauaguc     1020

uuggugggcg ggagcacaag gaucccaaag auucaaaagc ugcuacagga uuucuucaau     1080

ggaaaagagc ucaacaaguc uaucaacccc gacgaagcug uagcguacgg ugcagccguu     1140

caggcugcca uacuguccgg cgacaaauca gagaaugugc aggaucuucu guugcucgac     1200

gucaccccuc ugagcuuagg gauugaaacg gcaggaggcg ugaugaccgu ccugaucaag     1260

cggaacacaa cuaucccaac caagcaaaca cagacuuuua ccacauauag ugauaaucag     1320

ccgggugugc ucauucaagu uuacgagggg gagcgagcca ugaccaaaga caacaaucuu     1380

cugggcaagu ucgaauugac uggaaucccu cccgcuccac gcggcgugcc ccagauugag     1440

guaacguuug auauagacgc caacgggauc cuaaaugucu cugcagugga uaaauccaca     1500

ggaaaggaaa acaaaauuac caucacuaau gacaagggua gacugagcaa ggaggauauc     1560

gaaaggaugg uucaggaggc ggagaaauau aaggcugaag acgagaaaca gcgggauaag     1620

gugucgucua aaaacucccu cgaaucauac gccuucaaua ugaaggcaac cgucgaggac     1680

gagaagcugc aaggcaaaau uaacgaugaa gacaagcaga aaauacuuga caagugcaau     1740

gagaucauua acuggcugga uaaaaaucag acagccgaaa aggaggaauu ugagcaccag     1800

caaaaagagu uggaaaaggu guguaacccu aucauuacca agcucuauca gagugcuggg     1860

ggaaugccag gcgguaugcc cgggggcuuc ccgggaggcg gggccccucc cagcggaggu     1920

gcauccucug gcccaacuau cgaggaagua gacugaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  1720
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt3)

<400>  1720
gggagaaagc uuaccaugau cagcgccucc agagcugcag ccgcgaggcu ggugggcgcu       60

gccgcaucuc gggggcccac cgccgcucgc caccaggacu cauggaacgg acucagucau      120

gaggcauucc gacuugucag ccguagagau uacgccuccg aagcuauuaa gggugccguu      180

gugggcauag accuggggac aacuaauucu ugcguagcgg ugauggaggg aaaacaagca      240

aaggucuugg aaaacgccga gggcgcuagg acgaccccuu cggugguugc cuuuacagca      300

gauggugaac gguuaguggg gaugccagcu aaacgccagg ccgucacuaa uccgaacaau      360

accuucuaug cgacaaagag acugaucgga aggcgguacg acgaucccga ggugcagaaa      420

gacauuaaga acguaccuuu uaagaucguu cgcgccucaa auggcgaugc auggguggag      480

gcucacggca aacuauauag cccaagucag auuggggccu ucguccucau gaagaugaaa      540

gaaaccgcug agaacuaccu gggacauacu gccaagaaug cagugaucac agugcccgcc      600

uauuuuaacg acucccaacg acaggcuacc aaagaugcgg gucagauauc uggccuuaau      660

guccugagag uuaucaacga accuacggca gccgcuuugg ccuacgggcu cgacaagagc      720

gaggauaagg ugauugcagu auaugaccug ggaggcggua cuuucgauau cuccauucug      780

gagauccaga aagggguguu ugaagucaag ucaaccaaug gagacacauu ccucggcggc      840

gaggacuuug aucaagccuu acugaggcac auagugaaag aguucaagcg ggaaacuggg      900

guugaccuua ccaaagauaa cauggcuuug cagcgugugc gcgaagccgc agagaaggcg      960

aaaugugagc ugaguagcuc uguccagaca gacauuaauc uaccauaccu caccauggau     1020

uccucaggac ccaagcaucu gaacaugaag uugacgagag cucaguuuga agguaucgug     1080

acugaccuga uuaggcggac aaucgccccu ugccaaaaag caaugcagga ugccgaggua     1140

agcaagagug acaucggcga aguuauuuug gucgggggaa ugacccgaau gccaaaagug     1200

cagcaaacug ugcaggaucu cuucggccgc gcuccgucua aggccgucaa ccccgacgag     1260

gcaguggcua uaggugccgc gauccaaggg ggcguucugg ccggagaugu gacagacgua     1320

uuacugcucg acgucacccc ucuuucccug ggcauugaaa cgcuuggggg aguguuuacc     1380

aaacuaauca auagaaacac aacuauacca accaaaaaga gccagguuuu cucgacagcu     1440

gcagaugguc agacucaggu ggagauuaag gucugucagg gcgagaggga aauggccggg     1500

gacaauaagc ugcucggaca guucacccug aucggcauuc ccccugcucc acggggugug     1560

ccccaaaucg agguaacauu ugauaucgac gccaacggga uugugcacgu uucugcaaaa     1620

gauaagggca ccggacgcga acagcagaua gucauccagu ccucaggcgg gcuuaguaaa     1680

gacgauauug agaauauggu gaagaacgcg gaaaaguacg ccgaggagga cagaaggaaa     1740

aaggaacgug uggaggcugu caauauggcc gaaggaauca uccacgauac ugagacgaaa     1800

auggaggagu ucaaggacca acugccggca gaugaaugca acaaauugaa ggaagagauu     1860

agcaagaugc gggaacuccu ggcucgaaaa gacuccgaga caggugagaa uauaagacag     1920

gccgcaucua gcuuacagca ggccucacug aagcuauuug aaauggcuua uaaaaagaug     1980

gcgagugaga gggaaggcuc cgggagcucu ggaaccggcg agcaaaaaga agaucagaag     2040

gaggagaaac agugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  1721
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt3)

<400>  1721
gggagaaagc uuaccauggc cgacaaggag gcuggcggga gcgauggacc cagagaaacc       60

gcaccuacau ccgccuacuc uucaccagcg aggagucugg gugacacugg caucacgccg      120

cucagccccu cccacauugu gaacgauacc gacucuaaug ucucggagca gcaaucauuc      180

cuuguugugg uagcugugga uuuugggaca acuagcagug gauaugccua cuccuucacc      240

aaagaaccug agugcauaca ugucaugcgg cgcugggaag gcggugaccc aggggugucu      300

aaccagaaga cacccaccac uauccuguug acaccugagc gaaaauuuca cagcuucgga      360

uaugcagccc gugauuuuua ccaugacuua gauccaaaug aggcuaagca guggcuguau      420

cuagaaaaau ucaagaugaa gcuccacacc acgggcgacc ugacuaugga uaccgaccuu      480

acagcagcca acggcaaaaa gguuaaagcu cuggagauuu uugccuacgc guugcaguau      540

uucaaggaac aagcacucaa agagcugucc gaucaggccg ggucagaguu ugaaaauagu      600

gacgugagau gggucaucac ugugcccgcu auuuggaagc agccugccaa gcaguucaug      660

aggcaagcag cuuaccaggc cggacuggcg agcccagaga acucugaaca gcucaucaua      720

gccuuagagc cggaagcagc uuccaucuac ugucggaaac ugcgccuuca ucagaugauu      780

gaguugucaa gcaaggccgc uguaaauggu uauaguggcu cugacaccgu uggggccgga      840

uuuacacaag caaaagagca caucagaagg aaccggcagu cccgcaccuu ccugguggaa      900

aaugucauug gcgagaucug gagcgaacua gaggaaggug auaaguacgu gguggucgac      960

uccgggggag gcacgguuga ucucacugug caccagauac gacugcccga gggccaucuu     1020

aaagagcugu auaaggccac agggggaccu uacgguucuu ugggcguaga cuaugaauuu     1080

gagaaacucc uguacaagau uuucggggaa gauuucaucg agcaauuuaa gauuaaaaga     1140

ccagcugcgu ggguggacuu aaugaucgca uucgaaucca ggaagcgggc cgcugccccc     1200

gaucguacca acccucugaa uaucacucuc ccauuuucau ucauugacua uuacaaaaag     1260

uuucgcggac acagugucga gcaugcacuu agaaaaagca acguggauuu cguuaagugg     1320

uccucucagg gcaugcugag gaugagcccc gacgccauga augcuuuguu uaagccgaca     1380

auagauucaa ucauugagca ccuacgggac cuguuccaga aaccugaagu gaguaccguc     1440

aaguuucucu uccugguggg uggguuugcc gaggcacccc uucugcagca agcgguacag     1500

gcugccuucg gcgaccagug ccgaaucaua auuccacagg auguuggauu gacgauccuc     1560

aaaggcgcag ugcuguuugg guuagacccu gccgucauca aggugcgcag aucgccccug     1620

accuacggag ucggugugcu aaacagguau guugaaggca aacacccacc cgagaagcuc     1680

cuggugaagg augggacacg gugguguacu gacguauucg auaaauucau uagcgcugac     1740

caaucugucg cccuuggaga guuggugaag cgcucauaca ccccugcaaa accaagucag     1800

cugguuaucg ugauuaauau auauagcucc gaacaugaua acgucucuuu uaucacagac     1860

ccgggcguga agaaaugcgg uacucucaga cuggaucuua ccgggacauc gggcaccgcu     1920

guacccgcca ggcgugagau ucagacucug augcaguucg gagacacgga aaucaaggcg     1980

acagccaucg auauugcuac cagcaagucc gugaaaguug gcauagacuu uuugaacuac     2040

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  1722
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt3)

<400>  1722
gggagaaagc uuaccaugcu ggccgugccc gagaugggcc uccaggggcu uuacaucgga       60

agcuccccug aaagaucucc agucccguca cccccuggua guccaaggac ccaagagagc      120

ugcggcauug cuccccugac accuucccag ucuccaaagc ccgaaguucg ggcaccucag      180

caggccucgu ucucaguggu aguggcgaua gacuuuggga cuacgagcag uggauaugcu      240

uucuccuuug ccucugaucc agaggcaauc cacaugaugc gcaaauggga aggcggugac      300

ccgggggucg cccaccaaaa gacccccaca uguuuguuac ugacuccuga gggagcuuuc      360

cacagcuuug gcuacaccgc acgagauuau uaccaugacc uagauccaga ggaagcccgu      420

gacuggcucu auuucgagaa auuuaagaug aaaauucacu ccgcuacaga ucugacccuu      480

aagacucagc uggaagccgu gaacggcaag acaaugcccg cguuggaggu uuucgcacau      540

gcccucagau uuuucaggga gcacgcucug caggaacugc gggagcaguc accuagucuc      600

ccagaaaaag acaccgugcg cugggucuua acggugcccg ccaucuggaa gcaaccggca      660

aaacaguuua ugagagaggc ugccuaccug gcggggcuug uaagcaggga aaaugccgag      720

caguugcuga uugcacuaga gccugaagcu gccucuguuu auugccggaa gcuccgccug      780

caccagcuuc uggauuuguc cggacgagcu cccgguggcg ggagacucgg agagaggcgg      840

ucaaucgaca gcaguuuccg ucaagcccgc gaacagcuga gaaggucucg gcauucccga      900

accuuuuuag uggagagcgg cgucggugaa cugugggcag agaugcaggc cggggaucgc      960

uacguggugg cugacugugg aggcggcacu gucgaucuca caguucacca acuugagcag     1020

ccacauggga cucugaaaga auuguacaag gcgucgggag guccuuaugg cgcagugggg     1080

guagaccuag ccuucgagca gcugcucugc agaauauucg gagaagacuu uaucgcuacc     1140

uucaagaggc agcggcccgc cgcaugggug gaucugacaa uugccuuuga ggcucgcaaa     1200

agaaccgccg gcccacacag ggcgggugca cuuaacaucu cucugcccuu cuccuuuauu     1260

gacuucuacc guaagcaacg ggggcacaau gucgaaacgg cuuugcgaag aucaagugug     1320

aacuuuguua aauggagcuc ccagggcaug cucaggaugu cuugugaggc caugaaugag     1380

cuguuccagc cuacugugag cggaaucaua cagcauauug aagcauuacu ggcccgccca     1440

gagguccaag gcgugaagcu acucuuucug guagggggau ucgcugaauc agccguucuu     1500

cagcacgcag ugcaggcugc cuugggugcg cggggccuga gagucguggu cccgcaugau     1560

guggggcuca caauccugaa aggagccguu cuuuuuggcc aggcucccgg ugugguaagg     1620

guccgccgaa guccucugac cuauggggug ggcguuuuga accgguucgu gccaggacgu     1680

caucccccug agaagcuccu ggucagagac ggcaggcgcu ggugcacuga uguguuugag     1740

cgguucguag cagccgaaca auccguggcu uuaggggagg aaguuagaag gagcuacugu     1800

ccagcccgac ccggacagcg ccggguccug auuaaucuau auugcugugc agcggaggac     1860

gccagauuca ucacagaucc gggugugagg aaaugcggcg cucucucucu ggaacuugag     1920

ccugccgacu gugggcagga uaccgcagga gcuccacccg gccgucgcga gauccgggcc     1980

gcaaugcagu uuggugacac ggaaauuaag gugaccgccg ucgauguuuc aacaaacaga     2040

agugugaggg cuagcauaga cuucuugucc aauugaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  1723
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt3)

<400>  1723
gggagaaagc uuaccauggc ccgggagaug accauccugg gcagcgcugu gcucacacuu       60

cuguuggcag gguacuuagc ccagcaauau cugccccuac cuacuccaaa ggucauugga      120

auagaccucg guacgaccua cugcuccguu ggcguguucu uuccggggac aggaaaagua      180

aaggugaucc ccgaugaaaa cggccacauu ucuaucccuu caauggucag uuucacugac      240

aaugaugugu auguugguua cgagagcgug gaacuggcgg acuccaaccc acagaauacc      300

auuuaugaug cuaaaagguu uaucgggaag auauucacag ccgaggaacu ugaggcagag      360

aucggacggu accccuuuaa aguccugaac aagaauggca ugguggaguu cucuguaacc      420

ucgaacgaaa cuauuacagu uucaccugaa uaugugggca gccgcuugcu ccugaagcug      480

aaagagaugg ccgaggcuua ccucgggaug ccagucgcaa augccgugau cagugugccc      540

gcugaauuug acuuaaagca gcgaaacucc accauugagg ccgcgaaucu ggcaggacuu      600

aaaaucuugc gugucauaaa cgaaccuacg gccgcugcca uggcauacgg ucugcauaag      660

gcugauguuu uccacgugcu aguaauugac cucggcgggg gaacucugga ugugucucuu      720

cugaauaaac agggcgguau guuuuugacc agagccauga gcgggaacaa uaagcucgga      780

ggccaagacu ucaaccagag gcuguuacag uaucuguaca agcagaucua ucaaacauac      840

ggcuuugucc caucccggaa agaggaaauu caucgccuca gacaggcggu ggagaugguu      900

aaguugaauc ugacuuugca ccagucagcc cagcuaagug ugcugcucac cgucgaggaa      960

caagauagga aagagccgca uagcucugac acagaacugc ccaaggauaa acuuuccuca     1020

gcagacgacc accgggugaa cagcggguuc ggacgcgguc ugagugauaa gaaaucuggc     1080

gagucccagg uauuguuuga aaccgagauc agccgaaaac ucuucgacac gcugaacgag     1140

gauuuauucc agaagauccu gguuccuauu caacaggugc uaaaggaagg gcaccucgag     1200

aagacugaaa uagacgaggu cgugcugguc ggaggcucga caagaauccc aaggauuaga     1260

caggugaucc aggaauuuuu cgguaaagau cccaauaccu cuguugaccc ugaucuugcu     1320

gugguaacug gggucgccau acaagcuggc auugacggag gcuccuggcc acuucaggug     1380

ucagcccugg agauccccaa caagcaucuc cagaaaacaa auuuuaacug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  1724
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt3)

<400>  1724
gggagaaagc uuaccauggc cgcuaucggc gugcaccugg ggugcaccag cgcauguguc       60

gccguuuaca aggacgguag agcgggagug guagcuaacg augccggcga cagggugaca      120

cccgcagucg uggccuauuc cgagaaugaa gagauuguug ggcucgcugc aaaacagucu      180

cggauacgca acaucucaaa uacugugaug aaggucaaac aaauucuugg acgaaguagc      240

uccgauccuc aggcccagaa guacaucgcu gaaucuaaau gccuggugau ugagaagaac      300

ggcaaguugc guuaugaaau cgacacgggu gaggagacca aauucguaaa uccagaagau      360

guugccagau uaauauuuuc gaagaugaaa gagacagcgc auucagugcu ggggagcgac      420

gcaaacgaug ucgugaucac ugugccguuc gacuuuggag aaaagcagaa aaaugcccua      480

ggcgaggcug ccagggcagc uggcuucaac guccuccggc ugauucacga gcccagugcc      540

gcgcuucugg ccuacgggau cggacaagau uccccuaccg guaagucuaa uauuuugguu      600

uuuaagcucg gcgggacaag ccugucccug ucagugaugg aaguaaacag uggaaucuau      660

cgcgugcuca gcaccaauac ugacgauaac auaggcggug cacauuucac agagaccuua      720

gcucaguacc uggccucuga auuucagaga uccuucaaac acgacgucag ggggaaugcu      780

cgggccauga ugaagcugac gaacucagca gagguggcca aacauagcuu gaguacucug      840

ggaucugcua auuguuuucu agauucccuc uaugaaggcc aggacuucga cugcaacguu      900

agccgcgcgc gauuugagcu gcuuuguucg ccacuguuca acaagugcau ugaggcaauc      960

agaggcuugc ucgaucaaaa uggguuuacc gccgacgaua uuaacaaagu gguccugugu     1020

ggagguucuu ccaggauccc caaguuacag cagcugauca aagaccucuu cccugcugug     1080

gaacuucuua auucaauucc acccgaugag guaauaccua ucggcgccgc aauugaagcc     1140

gggaucuuga uaggaaagga gaaccuacug guugaagaca gucucaugau ugagugcagc     1200

gcucgggaua uccuggugaa gggcgucgac gaguccggug ccucucguuu cacagugcuu     1260

uuuccaagcg ggacuccgcu gcccgcacgc agacagcaca ccuugcaagc gccuggcuca     1320

aucaguuccg ucugucucga acuguacgag agcgauggca aaaauucugc uaaggaagag     1380

acaaaauucg cccagguggu uuuacaggac cuggauaaga aagaaaacgg acuaagggac     1440

auucucgcag ugcugaccau gaagcgggac gggucacuuc acguaacgug cacugaucaa     1500

gagacaggaa agugugaggc caucaguauu gaaauagcua gcugaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  1725
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt3)

<400>  1725
gggagaaagc uuaccaugag cguggucggc cuggacguug ggucccaguc uugcuacauc       60

gccguggcua gagcaggagg uauugagacc auagccaacg aguucucaga uagguguaca      120

cccaguguaa ucagcuuugg cuccaagaau cggacuauug ggguggcggc uaaaaaccaa      180

cagaucacgc acgccaauaa caccgucucu aauuucaagc gcuuucaugg acgagcauuc      240

aacgacccuu uuauucagaa agagaaggaa aaucucucgu augaucuugu gccacugaaa      300

aacggcggug uugggaucaa ggugauguac augggagagg aacacuuguu cucagucgag      360

cagauaacag ccauguuacu gacuaagcua aaagagaccg cugaaaauag ccucaagaaa      420

ccggugacag acugcguaau caguguuccc uccuuuuuca ccgaugcaga gcguagaucu      480

gugcuggacg ccgcucaaau ugucggccuu aacugucuga gguugaugaa ugauaugacu      540

gccguggcgc ucaacuaugg caucuacaag caggaccugc cuagccugga ugaaaaacca      600

cggauugugg ucuuuguuga cauggggcau uccgcauucc aggugucagc cugcgcuuuu      660

aauaagggaa agcucaaagu auuagguaca gccuucgauc ccuuucuggg cgggaagaac      720

uucgacgaga aacuugugga gcacuucugu gcagaauuua agaccaaaua uaaguuggau      780

gcuaaaagua agauccgcgc ccugcuaaga cucuaccagg agugcgaaaa gcugaaaaag      840

cugaugagcu cuaauuccac ggaccuuccu uugaacauag aguguuucau gaacgacaaa      900

gaugucucag gaaagaugaa uaggagccaa uuugaagaac ucugcgcgga gcuguuacag      960

aaaauugaag ugccacugua uagucuccuu gagcagacuc aucugaaggu ugaagacgug     1020

ucugccgucg agaucguggg cggugcaacc cggauucccg cuguaaagga acgcaucgcc     1080

aaauucuuug ggaaggauau cuccacaacu uugaacgcug acgaggccgu ugcacgagga     1140

ugugcccuac agugcgcuau ucugagcccu gcguucaaag ugagagaguu uucggucacc     1200

gaugcagugc cauucccgau aucucucauc uggaaucacg acuccgaaga uacagagggc     1260

guccacgaag uguuuucaag gaaccaugcc gcucccuuca guaagguucu gaccuuucuu     1320

cggcguggcc cuuucgagcu ggaagccuuu uacagcgacc cacaaggggu gcccuacccu     1380

gaggcaaaaa uuggacgcuu cguaguccag aauguguccg cccagaagga uggugagaag     1440

ucuagaguua aagugaaggu cagggugaac acgcacggca ucuucacuau aagcacagcu     1500

ucaaugguag aaaaagugcc aaccgaggaa aaugagauga guuccgaggc cgacauggaa     1560

uguuugaacc aacggccccc ggagaauccu gauacugaca agaacguuca gcaggacaau     1620

agcgaagcag ggacacagcc ccaaguccag accgaugcgc agcagacguc ucaaucacca     1680

ccuagucccg agcucaccag cgaagagaac aaaauuccag acgcugauaa ggccaaugag     1740

aagaaagugg accagccccc ugaagcaaag aaaccaaaga ucaaaguggu caacguugag     1800

cugccgaucg aagccaauuu aguguggcag cugggaaagg aucuacucaa cauguauauu     1860

gagacagaag gcaaaaugau caugcaggac aagcuggaga aggagcgaaa cgaugcuaaa     1920

aaugccgugg aagaguacgu auaugaauuu cgcgacaaac uuugcggucc cuacgagaaa     1980

uucauuugcg aacaagauca ucagaacuuu uugagacugc ucacugagac cgaggacugg     2040

cuguaugaag agggggaaga ucaggcaaag caggcuuacg ucgacaaacu ugaggagcug     2100

augaagauag gcacaccugu gaagguuagg uuccaagaag ccgaggaacg gccaaaaaug     2160

uuugaggaau ugggacagcg ccuccagcac uaugcgaaga ucgccgcuga uuucagaaau     2220

aaagacgaga aguacaacca cauugacgag uccgaaauga aaaaggugga gaagucuguc     2280

aaugaaguga uggaguggau gaacaauguu augaacgcac aagccaaaaa gucgcuggau     2340

caggaccccg ugguaagggc ucaggaaauc aaaacuaaga ucaaagaguu aaauaacacc     2400

ugugagccug ucgugacaca gccaaagccc aagauugaaa gcccgaaacu ggagcguacc     2460

ccuaauggcc caaacauaga uaagaaagaa gaggaccuag aagauaagaa uaacuuuggg     2520

gccgagcccc cucaucaaaa uggagagugc uaccccaacg aaaagaacuc cgugaauaug     2580

gaccucgauu gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  1726
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt3)

<400>  1726
gggagaaagc uuaccauggc cgacaaggug agaaggcagc ggccccgccg acgugucugc       60

ugggcucugg uugcagugcu ccuugccgau cuguuggcgu uaagcgacac ccuggcugua      120

auguccgugg aucuaggcuc ugagucaaug aaagucgcca ucgugaagcc ugggguucca      180

auggaaauug ugcucaacaa agagaguaga aggaagacac cggucauagu gacucugaaa      240

gaaaaugagc gguucuuugg agacagcgca gccuccaugg cuaucaagaa ccccaaggca      300

acgcuucgcu acuuccaaca ccuguugggu aaacaggccg auaauccuca uguagcucuc      360

uaucaggcca gauuuccaga acacgagcug accuucgacc cccagaggca aacaguucau      420

uuucagauuu cuucgcagcu gcaguucuca ccugaggaag ugcucggcau ggucuuaaac      480

uacagccgga gucuggcgga ggauuuugca gaacaaccaa ucaaggacgc cgugauuacu      540

gugcccgucu ucuuuaauca ggcugagcgc cgagccguuc uucaggcagc uagaauggcc      600

ggguugaaag ugcugcagcu aaucaacgau aauaccgcga cagcccucuc cuauggagua      660

uucaggcgga aggacauaaa caccacugca caaaauauca uguuuuacga uaugggcucu      720

gguagcacag uguguaccau ugucacguau cagaugguga aaacuaagga ggcugggaug      780

cagccucaac ugcagauccg uggaguuggc uucgaccgca cccuuggcgg gcuggaaaug      840

gaguugagac ucagggaacg gcuggccgga uuauuuaacg agcagcgaaa gggucagcgc      900

gcuaaagaug ugagagaaaa uccaagggcc auggcaaagc ugcuccggga ggccaaccgc      960

cuuaaaacag uccuguccgc uaaugcggac cacauggcac aaauugaggg cuugauggac     1020

gauguggacu ucaaggccaa aguaacuaga guugaguucg aggaacuaug cgcugaucug     1080

uuugagaggg ugccggggcc cguccagcag gcccuccagu cagcagaaau gagucuggac     1140

gagaucgagc aagugauacu ugucggaggc gccacccgug ugccucgggu ucaggaagug     1200

cuguugaagg cuguagguaa agaggaacuc gggaagaaca uuaaugccga ugaggcagcg     1260

gcuaugggag ccgucuacca ggcagccgcu cugagcaagg ccuucaaagu gaagccauuu     1320

guugugcgag acgcagucgu guaucccauc uuaguagagu ucacaagaga gguggaggaa     1380

gaaccuggca uucauucucu gaaacacaac aagaggguuc uauuuucccg caugggccca     1440

uacccccagc ggaaagucau caccuucaac agauacucac acgauuuuaa uuuccauauc     1500

aacuaugggg accucggauu ucuggguccg gaagaucuua ggguguucgg cagccaaaau     1560

uugacgacug ugaagcugaa gggggucgga gacaguuuua aaaaguaccc ugauuaugag     1620

ucuaaaggca uuaaggcuca cuucaaccuc gacgaguccg guguucugag ccuugaccgc     1680

guggaaucgg uguuugagac acugguagaa gauucugccg aggaagaguc caccuugacu     1740

aaacucggga auacaauauc aagucuguuc ggcggaggca ccacgcccga cgcgaaggag     1800

aacgggaccg auacagucca ggaagaggaa gagagcccag ccgaaggauc caaggacgag     1860

ccuggugaac agguggaauu aaaagaggaa gcugaggcac ccguugaaga uggcucucag     1920

ccacccccuc cagagccgaa gggggacgcc acucccgagg gagaaaaagc uaccgagaag     1980

gaaaauggcg auaaaagcga ggcccaaaag ccuucagaga aggcagaagc ggguccagag     2040

gggguggccc ccgcuccuga aggcgagaaa aagcagaaac cagcccgaaa gcggcguaug     2100

gucgaagaga ucggagugga gcugguugug cuagaccucc ccgaucugcc ggaagacaaa     2160

cuugcacaga guguacaaaa guugcaggau cugacacuca gagaccugga gaaacaggaa     2220

agggagaagg cugccaacuc cuuagaagca uucauuuuug agacucagga uaagcuguac     2280

caaccugagu aucaggaagu cagcaccgag gaacagcgcg aggaaaucuc uggcaaacuu     2340

ucagccgcua guacaugguu ggaggacgag ggggugggag cgaccacugu gaugcucaag     2400

gaaaaacugg ccgagcuacg gaagcugugu cagggucucu ucuuuagagu cgaagagagg     2460

aaaaaguggc cagagcgacu gagcgcacuu gacaauuugc ugaaccauuc cucuauguuc     2520

uuaaagggcg cucgccucau acccgaaaug gaucaaauuu uuacggaggu ugaaaugaca     2580

acccuggaga aagugaucaa ugaaacuugg gccuggaaga acgccacccu ugcugagcag     2640

gcaaaacugc cugccacaga gaagcccgua uugcucucga aagacaucga agcgaagaug     2700

auggcucugg aucgggaggu gcaguaccua cugaauaagg ccaaauucac caagccaaga     2760

ccuaggccca aagacaagaa cgggacucgu gcagaaccac cgcucaaugc cagcgcuucc     2820

gaucagggag agaaagucau uccucccgca ggccaaacag aagacgccga gccaaucuca     2880

gagcccgaaa agguggagac ggguagugaa ccuggggaua ccgagccacu ggaacuuggc     2940

ggacccggcg cggagccuga gcagaaggaa cagucuacug ggcaaaaacg cccguugaag     3000

aacgacgagc ugugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1727
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt3)

<400>  1727
gggagaaagc uuaccaugcc cgaggaaacc cagacacaag accagccuau ggaggaagag       60

gaaguggaga cuuucgccuu ucaggcugag aucgcacagc ugaugagccu cauuauaaac      120

acguucuacu ccaauaagga aaucuuucuu agagagcuga uuucuaacuc aagugaugcc      180

uuggacaaaa ucagguauga gagcuuaacc gauccaucca agcuggacuc uggcaaagag      240

cuacacauua aucucauccc gaacaagcaa gaucggacac ugacuauagu cgacaccggg      300

aucggaauga caaaagcgga ucuuauuaau aaccugggua ccaucgcuaa gucgggcacu      360

aaggccuuca uggaggcauu gcaggccggg gcugacauuu caaugaucgg acaguuuggc      420

guugguuucu acagcgcaua ucucguggcc gaaaaaguaa cagugauaac caagcauaau      480

gaugacgagc aguacgcuug ggaaaguucc gccgggggau cuuuuacggu ccgcacugau      540

accggcgagc ccaugggccg agggacaaaa gugauucugc accugaagga agaccaaacu      600

gaguaucucg aggaacguag aaucaaagag auuguuaaga agcauagcca guucaucgga      660

uacccuauca ccuuauuugu ggaaaaagag agggauaagg aagucuccga cgacgaggcg      720

gaggaaaaag aggauaagga agaggaaaaa gagaaggagg aaaaagaguc agaagacaag      780

ccagagauug aggauguggg uagugacgaa gaggaagaga agaaagaugg cgacaagaaa      840

aagaaaaaga agauaaaaga aaaguauauc gaucaggagg agcugaacaa aacaaagccc      900

auuuggaccc ggaauccuga cgauaucacg aacgaagagu acggggaguu cuacaaaagc      960

cuuacuaaug acugggaaga ucacuuggca guaaagcauu uuucuguuga aggacagcug     1020

gaguuccgcg cccuacucuu ugugccaaga agggcucccu ucgaccuguu cgagaaccgg     1080

aagaaaaaga auaacauaaa acuuuauguc cgccgagugu uuauuaugga caauugcgaa     1140

gaacugaucc cugaauacuu gaacuucauc agaggcgugg ucgauuccga ggaccuccca     1200

cugaacauuu caagggaaau guuacaacag agcaagaucc ugaaaguuau ucggaagaau     1260

cucgugaaga aaugucuuga gcuguuuaca gaguuggccg aagauaagga gaacuauaaa     1320

aaguucuacg aacaguuuag uaaaaauaua aagcuaggua uccacgagga cucucaaaac     1380

cguaaaaagc uguccgagcu ccugcgcuau uacaccagcg caucggggga ugaaauggua     1440

ucucuuaagg acuauugcac uagaaugaaa gagaaucaga agcacauuua cuacaucaca     1500

ggagaaacca aagaucaggu ggcuaacucc gccuucgucg agaggcugcg gaagcauggc     1560

uuggaaguga ucuauaugau ugagccgaua gacgaguacu guguucagca acucaaagaa     1620

uuugagggca agacgcuggu gucagucacc aaggaagggu uagagcugcc cgaagaugag     1680

gaggagaaaa agaaacagga agaaaagaaa acaaaguucg agaaucuaug caagaucaug     1740

aaagacauuc ucgaaaagaa aguggagaag guaguuguga guaaccgacu ggucacuagc     1800

ccuuguugca ucgugaccuc cacauaugga uggacugcga auauggagcg cauuaugaaa     1860

gcccaggcac uuagagauaa cucuaccaug gguuacaugg cugccaagaa gcacuuggaa     1920

aucaauccag accauagcau aaucgagaca cugaggcaga aagcugaagc cgauaagaac     1980

gacaaaucag ucaaggaccu cgugauucug cuuuaugaga ccgcacuguu gaguuccggc     2040

uuuagccucg aggaucccca aacucacgcc aaucggaucu accgcaugau uaaacugggg     2100

uuaggaaucg acgaagauga cccuacggcu gaugacacau cugcggcagu uaccgaggaa     2160

augccacccc uggagggcga ugacgauacu ucaagaaugg aagaggugga cugaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  1728
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt3)

<400>  1728
gggagaaagc uuaccaugga cagcuccaag cuggauucug gcaaagggcu ccacaucaac       60

cuugugccca auaagcagaa ccaaacccug acaauugucg acacuagaau aggaaugacg      120

aaaaccgauu ugaucaauaa cuuagguaca guuacuaagu caggcaccaa agccuucaug      180

gaggcucugc aggcagacgc cgauauuagu augaucgggc auuuuggagu gggcuucuac      240

agcgcguauc uaguagcuaa gaaggugaca gucauuucca aacacaauaa cgacgaacag      300

uacaccuggg agucuucggc cgguggguca uuuacuguga ggacagauga augaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  1729
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt3)

<400>  1729
gggagaaagc uuaccaugcc cgaggaagug caccauggcg aggaagaggu cgaaaccuuc       60

gccuuucagg cugagaucgc acaacugaug agccucauua uaaacacauu cuacuccaau      120

aaggagaucu uucuuagaga acugauuucu aacgccucag acgcguugga uaaaaucagg      180

uaugagaguu uaacugaccc uagcaagcug gauuccggga aagaacuaaa gauugacauc      240

auaccaaauc cgcaggagcg gacgcucacc cugguugaua caggaaucgg uaugacuaaa      300

gcugaccuua uuaacaaucu gggcaccauc gccaagucug ggacaaaggc auucauggag      360

gccuugcagg cuggagcaga uauuucgaug aucggccagu uugguguggg guucuacuca      420

gccuaucucg uagcugaaaa aguggucgug auaaccaagc acaacgacga ugagcaauac      480

gccugggaaa gcagugcggg aggcuccuuu acuguucgcg cagaccaugg cgagcccauu      540

gggcgaggaa caaaagugau ccugcaccug aaggaagauc agaccgagua ucucgaggaa      600

cguagaguca aagagguggu aaagaagcau ucucaguuca uugguuaccc uaucacguua      660

uaucuggaaa aagagaggga aaaggagauc agcgacgaug aggccgaaga ggaaaaaggc      720

gagaaggaag aggaggacaa agacgaugaa gagaagccaa aaauugaaga cguugggucc      780

gaugaggagg acgauucagg aaaggacaag aaaaagaaaa cuaagaaaau aaaggaaaag      840

uacaucgauc aggaggaacu uaauaaaacc aagcccauuu ggacacggaa cccugacgau      900

aucacucaag aggaauacgg cgaguuuuau aaaaguuuga ccaaugacug ggaggaucac      960

cuggcuguga agcacuucag cgucgaaggu cagcuagagu uucgcgcccu ccuguucaua     1020

ccaagaaggg cacccuuuga ccuuuucgaa aacaaaaaga agaaaaauaa cauuaagcug     1080

uacgugcggc gcguguucau cauggacucu ugcgaugagu ugaucccuga auaucucaau     1140

uuuauucgag gggucguuga cuccgaggau cugccauuaa acaucucaag agagaugcug     1200

cagcagagca aaauucucaa ggugauaagg aaaaauaucg uaaagaagug ucuugaacug     1260

uucagugagu uggcugaaga caaagagaac uacaagaaau uuuaugaagc cuucucuaag     1320

aaccuaaaac ugggcauuca ugaggauucc acaaaucggc gucgccucag cgagcugcuu     1380

agauaccaca ccucgcaauc uggagacgaa augacguccc ugucagagua ugugaguagg     1440

augaaggaaa cucagaaaag caucuacuac aucacaggcg aguccaagga gcaggucgcg     1500

aacucugccu uuguggaacg gguucgaaag cgcggguucg agguggucua uaugaccgaa     1560

ccgauugaug aguacugcgu gcaacaguug aaagaauuug acggaaagag ccucguauca     1620

guuacuaaag agggucugga guuacccgaa gaugaggaag agaagaaaaa gauggaagag     1680

aguaaggcaa aauucgagaa ucuguguaag cuaaugaaag aaauacucga caagaaagug     1740

gagaagguca caaucuccaa cagacuggug agcucuccuu gcuguauugu caccucaacg     1800

uauggcugga ccgcuaauau ggaaaggauc augaaggccc aggcccuucg ggauaacagu     1860

acaauggggu acaugauggc uaaaaagcau uuggagauua auccagacca ccccaucgug     1920

gaaacucugc gccagaaagc agaggccgau aagaacgaca aagcuguuaa ggaccucgug     1980

guacugcuuu uugagaccgc gcuguugagc uccggauucu cucucgaaga uccucaaaca     2040

cacucgaaua gaauauauag gaugaucaag cugggcuuag guauugacga ggaugaaguc     2100

gcagccgagg agccaaacgc ugccgugccc gacgaaaucc cgccucugga gggggaugaa     2160

gacgcaagcc guauggagga aguugauuga ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  1730
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt3)

<400>  1730
gggagaaagc uuaccaugag agcccugugg gugcucggcc uuugcugugu ccuguugacc       60

uucgggagcg uuagggcuga cgaugaggug gacguagaug gaacagugga agaggacuua      120

gguaaguccc gggaaggcuc ucgcacugau gacgaggucg ugcagcgaga agaggaggca      180

auccaacugg augggcuaaa cgccucacag auucgugaac ucagagagaa aagugaaaag      240

uuugcguucc aggcugaggu uaauaggaug augaaacuga uaaucaacag ccuuuacaag      300

aauaaagaga uuuuucugcg ggaauugauc uccaacgccu cugacgcacu cgauaagauu      360

cgccugaucu cgcugacgga cgagaaugcc cucucaggaa acgaagaguu aaccgugaag      420

auaaaaugcg auaaggagaa aaaucugcuu cacgucacag acacuggcgu ggguaugacc      480

agagaggagu ugguaaagaa ccuggggaca aucgcuaaaa gcggaaccag ugaguuccua      540

aauaagauga cugaagcaca ggaagauggc caauccacau cugagcucau uggccaguuu      600

gggguuggau ucuauagcgc cuuucuggug gcugacaagg ucaucgugac cuccaaacau      660

aacaaugaca cgcagcacau uugggaauca gauaguaacg aguucagcgu gaucgccgac      720

cccaggggua auacucuugg ccgggggacc acaauaacuc uggucuugaa ggaggaagcg      780

ucugauuacc ucgagcugga caccauuaaa aacuuaguua agaaauauuc ccaguuuauc      840

aauuucccua uuuacgugug gucaagcaag acagaaaccg uagaggaacc aauggaggag      900

gaagaggcag ccaaagaaga gaaggaggaa agugaugacg aggcugccgu ggaagaggaa      960

gaggaggaaa agaaaccgaa gacgaaaaag gucgagaaaa cuguguggga uugggaacug     1020

augaacgaca ucaagcccau cuggcaacgc ccuucuaagg agguugaaga ggaugaguau     1080

aaagcauuuu acaaguccuu cagcaaagaa ucggacgauc caauggcuua uauucauuuu     1140

acagccgagg gagaagugac cuucaagucu auacucuucg uccccacuuc cgcgccucga     1200

ggccuuuuug acgaguacgg uaguaaaaag ucagacuaca ucaagcugua ugugagaagg     1260

guauucauua cagaugacuu ucacgauaug augccaaaau acuugaacuu cguuaagggg     1320

guggucgaca gcgaugaccu accccugaau gugucccggg aaacccucca gcagcauaaa     1380

cugcuuaagg ucauccguaa aaagcuggug cgcaagacgu uggauaugau uaaaaagaua     1440

gccgacgaua aauauaacga caccuuuugg aaggaguucg gaacaaauau caaacucggc     1500

guuaucgagg aucacucuaa cagaacuagg cuggcaaagu uacugcgguu ucagagcuca     1560

caccauccua ccgacauuac aagucuagau caauacgugg aacgaaugaa agagaagcag     1620

gacaagaucu auuucauggc uggcuccagc cgcaaagaag ccgagucuuc accauuugua     1680

gagagacucc ugaagaaagg guacgaaguc auuuaucuua cugagccggu ggacgaauac     1740

uguauacagg cuuugcccga guucgaugga aagagguuuc aaaauguugc caaagaaggu     1800

gugaaguucg acgagaguga gaagaccaaa gaaagccggg aggcagucga aaaggaguuu     1860

gaaccucugc ucaacuggau gaaagauaag gcccugaaag acaagaucga gaaggcugug     1920

guaucccagc gccuuacaga gucuccaugc gcgcuggugg caucgcagua cggcuggagc     1980

gggaauaugg aaagaauuau gaaagcccag gcuuaucaaa ccggaaagga uaucuccacu     2040

aacuacuaug ccucacagaa aaagacguuc gagaucaauc ccaggcaccc uuugauucgu     2100

gacaugcucc ggcgaauaaa agaagaugag gacgauaaga caguucugga cuuagcaguc     2160

gugcuguucg aaaccgccac ucuaagaagu ggcuaccucc ugccagauac caaggcuuau     2220

ggugacagga ucgagcgcau gcuucgguug ucucugaaca uugaucccga cgccaaagug     2280

gaggaagaac cggaagagga gccugaagag acagcagaag acaccacuga ggauacagaa     2340

caggacgagg augaggaaau ggacgucggg acggaugagg aagaggaaac cgcgaaggag     2400

agcacugcug agaaagacga acucugagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  1731
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt3)

<400>  1731
gggagaaagc uuaccauggc cagagagcug agggcucucc uucugugggg ccggcgcuug       60

cgacccuuac ugcgugcucc ugcccuagcg gcugugccag ggggaaagcc gauccucugc      120

cccagaagga ccacagccca gcuggguccu cggcgcaacc cagcauggag ccuucaagcc      180

ggcagacugu ucuccacuca gacggcugaa gacaaagagg aacccuugca cucuauuaua      240

ucaaguaccg agagcgucca gggguccaca ucuaagcaug aauuucaggc agagacuaaa      300

aagcuccugg auaucguugc caggucgcug uacucagaga aagaaguguu cauucgggag      360

cucaucagca augcuaguga cgccuuagaa aagcugcgcc acaagcuagu auccgaugga      420

caagcguugc cugagaugga gauucaucug cagaccaacg cagaaaaagg cacaaucacc      480

auacaggaca cugguaucgg gaugacacag gaggaacuug ugucuaaucu cggaaccauu      540

gcccgaagcg gcuccaaggc uuuucuggau gcccuucaaa accaggcaga ggcuucaagu      600

aaaaucauug gccaguucgg ggucggauuu uauagcgccu ucaugguggc ggacagaguu      660

gaaguguacu cuagguccgc cgcaccaggu ucacugggcu aucagugguu gagcgauggg      720

aguggagucu uugagaucgc ugaggccucu ggcgugcgga cggguacuaa gauaauuauc      780

caccucaaau ccgacuguaa ggaauuuagc ucggaggcuc guguacgcga uguugugacc      840

aaguacucua auuuugucuc cuucccccug uauuuaaacg ggagaaggau gaauacacug      900

caagccauuu ggaugaugga cccuaaagau gugcgggaau ggcagcauga ggaauuuuac      960

cgauaugugg cacaggccca cgacaagcca cgcuacacuc uccacuacaa aaccgaugcu     1020

ccgcuuaaca ucagaucaau cuucuauguc cccgacauga agccuaguau guuugacguu     1080

agcagggagc ugggauccuc uguggcguug uacagccgga aaguacuaau ucaaacaaag     1140

gcaaccgaua uacugccaaa auggcuccgc uucaucagag gcguggucga cucagaggau     1200

auuccccuga aucuuaguag ggaacuguug caggaguccg cccucauccg uaagcugcgg     1260

gacguguuac agcagcgacu gauaaaguuc uuuauugauc aaagcaaaaa ggacgcugaa     1320

aaauaugcca aguucuuuga ggauuacggc cuauucauga gagaagggau cguuacggca     1380

acugagcagg aggugaaaga agacaucgcc aagcuccuga gguaugaguc uucagcacuu     1440

ccuaguggac aguugacaag ccuguccgaa uacgccucuc gcaugcgggc agguaccaga     1500

aacauuuauu accucugcgc gccaaauagg caucuggcug agcacucgcc cuacuaugag     1560

gccaugaaga aaaaggauac ugaaguccuu uucuguuucg agcaguuuga cgaacugaca     1620

uugcuccauc ugcgcgaguu cgauaaaaag aaauuaauca gcguggaaac cgacauugua     1680

guugaccacu acaaggagga gaaguuugaa gaucgauccc cggcagccga gugccuguca     1740

gaaaaagaga cggaagaacu aauggcuugg augcggaacg ugcucggcag ucgugucacc     1800

aaugugaagg ucacacugag acuugacacu cacccugcca uggugaccgu uuuggagaug     1860

ggggcagcua ggcauuuccu gcgcaugcaa cagcucgcca aaacacagga ggagcgggcg     1920

cagcuguuac aacccacucu ggaaauaaac ccaagacacg cccuuaucaa gaaauugaau     1980

cagcucaggg cuucugagcc uggacuggca cagcuacugg uggaucagau uuaugaaaac     2040

gccaugaucg cugccggccu cguagacgau ccccgagcaa uggucggucg ccugaacgag     2100

cuuuugguga aggcgcugga gcggcauuga ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  1732
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt3)

<400>  1732
gggagaaagc uuaccauggg caagaucagc ucccugccca cccaacucuu caaaugcugu       60

uuuugcgacu uccuuaaggu gaaaaugcac acaaugucuu caagucaucu guuuuacuug      120

gccuuauguc ugcuaacuuu cacgagcucc gcuaccgcag ggccugagac acucugcgga      180

gccgaacugg ucgaugcgcu ucaguuuguu uguggugaca gaggcuucua uuuuaacaag      240

ccaacugggu acggaucuuc gucaaggcgg gcuccgcaga ccggcauugu ggaugagugc      300

uguuuccgca gcugcgaccu gcgacguuug gaaauguauu gugcaccccu caaaccugcc      360

aagagugcca gauccguaag ggcucagcgg cacacagaua ugccaaagac ccagaaagag      420

gugcaucuga agaaugcauc ucgcgguagc gccgggaaca aaaauuacag aaugugagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  1733
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt3)

<400>  1733
gggagaaagc uuaccauggg cauccccaug ggaaagagca ugcuggugcu ccuuaccuuc       60

cuggccuuug cuuccugcug uauugcagcc uacagaccuu cugagacauu gugcgggggu      120

gaauuagucg acacucugca guucguuugu ggcgauaggg gguuuuauuu cucacggcca      180

gcgagucgcg ugagccgacg uuccagagga auaguagagg aaugcuguuu uaggucuugc      240

gaccuagcuc uccuggagac guacugugcc accccggcaa aaucggaacg ggauguguca      300

acacccccua cuguccuucc agacaacuuc ccccgcuauc cugugggcaa guuuuuccaa      360

uacgauaccu ggaaacagag cacacagaga cugaggcggg guuugccagc ccuccugcgc      420

gcucgaagag ggcacguucu ggcaaaggag cucgaggccu uuagggaagc uaaacggcau      480

cgucccuuaa ucgcccugcc uacccaggac ccagcgcacg gaggcgcacc gcccgagaug      540

gccaguaauc gcaagugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  1734
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt3)

<400>  1734
gggagaaagc uuaccaugaa cagcuucucc accucugccu uuggccccgu ggcuuucuca       60

cuggggcucc uucuggucuu gccugcagcc uuuccagcgc cgguuccccc uggagaggac      120

aguaaggaug uggcugcccc acacagacag cccuuaacaa gcuccgaaag gaucgacaaa      180

caaauucggu acauacugga ugguaucucu gcacuacgca aggagacuug caauaaaucg      240

aacaugugug aaucaagcaa ggaggcccuc gcugaaaaua accugaaucu uccuaaaaug      300

gcagagaagg acggcugcuu ccagaguggg uuuaacgagg aaacgugucu gguaaagauu      360

aucaccggau ugcucgaguu cgaaguguau cuggaguacc ugcagaaucg auuugagucc      420

ucugaagaac aggcccgugc uguccaaaug agcacaaaag ugcucauuca guucuuacag      480

aagaaagcca agaaccugga ugcgaucacu accccagacc ccacaaccaa ugcaucccuu      540

uugacuaaac ugcaggccca aaaccagugg cuacaggaua ugacaaccca ucucauacug      600

agaucauuua aggaguuccu ucagaguagc cugagggcuu ugcggcaaau gugaggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  1735
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt3)

<400>  1735
gggagaaagc uuaccaugcc ccugcucugg cuuagaggcu uccuguuggc cagcugcugg       60

aucauuguga gguccucucc uaccccaggg ucagagggac acagugcugc accggacugu      120

cccagcugcg ccuuagcggc ucugccuaag gaugucccaa acucccagcc cgaaaugguu      180

gaggccguga aaaagcauau acuaaauaug cuccaccuga aaaagcggcc ugacguaaca      240

caaccagugc ccaaagcagc ccuucugaac gcuauccgca aguugcaugu cgguaaggug      300

ggcgaaaaug gguacguuga gauugaagau gacaucggac gacgugcaga gaugaacgag      360

cucauggaac agacuucuga gauuaucacg uuugccgaau cgggcaccgc uagaaaaaca      420

cugcacuucg agauaucaaa ggaggguagc gaucugagug uggucgaaag ggccgaggug      480

uggcucuuuu uaaaaguacc uaaggcgaau cggacucgca ccaaaguuac aaucagacug      540

uuccagcagc aaaagcaucc acaggggucc cuugacaccg gagaagaggc agaagaggug      600

ggcuugaagg gcgagagguc ugaacugcua cucagcgaga aagucgugga ugcccggaag      660

uccacuuggc acguguuucc ggucucaagu agcauucagc gccugcuuga ccaggggaaa      720

ucuucccugg auguucgaau cgcuugugaa caaugccagg agucaggagc cagcuuggug      780

cuccugggua agaaaaagaa aaaggaagag gagggcgaag ggaagaaaaa gggaggcggu      840

gaagggggag caggcgcuga cgaggagaaa gaacagaguc acagacccuu cuuaaugcug      900

caggccaggc aaucugagga ucauccucac cggcgucgca gaaggggccu cgagugugac      960

gggaagguaa acauuugcug uaaaaagcag uuuuucgugu ccuuuaagga uaucggaugg     1020

aaugacugga uaauugcgcc aagcgguuau caugccaacu acugcgaagg cgaguguccc     1080

ucgcacaucg cagggacauc uggauccuca cuuaguuucc acagcaccgu cauuaaucau     1140

uaucggaugc gaggccacuc cccuuuugcu aaccugaaau cuugcugugu gccaacgaag     1200

uugcgcccca ugagcaugcu auacuaugac gauggucaga auaucaucaa aaaggacauu     1260

caaaacauga uaguugaaga gugcgggugc ucaugaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  1736
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt3)

<400>  1736
gggagaaagc uuaccaugga cggccugccc gggagagccc ucggagcugc augccuucug       60

uuguuagccg cggguuggcu gggcccugag gcuuggggga gcccaacccc gcccccuaca      120

ccagccgcac ccccuccacc cccuccaccg ggaucccccg gcgguucuca ggauacuugu      180

acgucaugcg ggggauucag gcggccugag gaacuaggcc gcguggacgg cgauuuucuc      240

gaagccguca agcgacacau ccugagucgu cuucaaauga gagggaggcc aaacauuacc      300

caugcuguuc ccaaagcagc cauggugaca gcucugcgga aguugcacgc cggaaaagua      360

cgcgaggacg guagagugga aauaccucau cucgauggcc acgcgagccc aggggcagac      420

ggacaggaga gggucuccga gaucauuucu uucgccgaaa cugauggccu ggcuucguca      480

cgggugcgcc uguacuuuuu caucagcaau gaggguaacc agaaucucuu uguugugcag      540

gccaguuuau ggcuguaucu uaaguugcug cccuacgucc uagaaaaagg gucccgaaga      600

aaggugaggg uaaagguuua uuuccaagag cagggacaug gcgaccggug gaacauggug      660

gagaaacgug ucgaucucaa gcgcucuggc uggcacaccu uuccgcugac agaagcaauu      720

caggcucuuu ucgagagagg ggaaaggcgg cugaauuugg acgugcagug ugauagcugc      780

caagagcucg ccgugguccc uguuuuugug gaccccggag aagaguccca ccgaccauuc      840

guaguggucc aggcgcgccu gggugauuca agacauagga uccggaaacg cggcuuagag      900

ugugacggga gaaccaaccu gugcuguagg cagcaguuuu ucauagacuu ucgucucauc      960

ggauggaaug auuggauuau cgccccuacu ggcuacuaug guaacuacug cgaagggagu     1020

ugucccgcau aucuugcugg cgugccagga agcgccucuu ccuuccacac agcuguugug     1080

aaucaauacc ggaugcgagg ccugaacccc gggaccguca auucaugcug uauuccuacg     1140

aaguugagca cuaugaguau gcuauacuuc gacgaugagu auaacaucgu gaaaagagac     1200

guaccaaaua ugauaguuga agagugcgga ugcgccugag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  1737
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt3)

<400>  1737
gggagaaagc uuaccauggc ccugagagug cuccuucuga ccgcuuugac auuaugccac       60

ggcuucaacc uggacacuga gaaugcaaug acguuucagg aaaacgccag gggguucgga      120

caaagcgucg uucagcuaca ggguucccgg gugguagugg gcgcgcccca ggagaucguc      180

gcugccaauc aacgcggguc ucucuaccag ugugauuauu caaccggaag uugcgaaccu      240

auucgacugc aagugccagu ugaggcagug aacaugagcc uuggccuguc cuuggccgcu      300

acaacuucuc cgccccagcu ccuggcaugu gguccuaccg uccaucaaac augcucggaa      360

aauaccuacg ugaaggggcu guguuuucuc uucggaucaa acuuacguca gcagccacag      420

aaauuucccg aggcccugag aggcugcccu caagaggaca gcgauauagc uuuccuuauc      480

gacggcagug gguccauuau cccacacgau uuuaggcgga ugaaggaguu cguaucuacu      540

guuauggaac aguugaaaaa gagcaaaaca cuguuuuccc uaaugcagua uucagaagag      600

uuccgcauuc auuuuaccuu caaggaguuu caaaauaacc ccaauccuag aagucucgug      660

aagccaauca cgcagcugcu uggaaggacu cacaccgcca cagguauacg gaaagucgug      720

cgcgaacugu ucaacaucac uaauggcgcg cgaaagaacg cauucaaaau uuuggugguc      780

aucaccgacg gggagaaguu uggagauccg cucggcuacg aagacguuau ucccgaggcc      840

gauagagaag gugugaucag guauguaaua ggggugggag acgcuuuccg gagcgagaaa      900

ucucgucagg agcugaauac aauugccucc aagccuccac gcgaucaugu cuuucaggug      960

aacaauuucg aagcauuaaa gaccauccaa aaccagcuga gagagaaaau uuuugcuauc     1020

gaaggcacgc agacuggcuc aagcaguucu uucgagcacg aaauguccca ggagggguuu     1080

agcgccgcga ucacaucgaa cggaccccuc cuuucuaccg uugguuccua cgacugggcc     1140

ggcggggugu uccuguauac uucaaaggag aaaaguacau uuauuaauau gaccaggguc     1200

gauagcgaca ugaacgacgc auacuuggga uacgcugccg cuauaauccu acggaaucga     1260

gugcaauccc ugguacucgg cgccccucgc uaucagcaca uuggucuggu ugcaauguuc     1320

agacagaaca cggggaugug ggaaucuaau gccaacguga agggcaccca gaucggagcu     1380

uacuuuggcg cgagccuuug uucagucgau guggacagua auggguccac agaucugguc     1440

uugauaggag caccacauua uuacgagcaa acuaggggug gccaggugag cguuugcccc     1500

cucccgcggg ggcgcgccag auggcagugu gacgcugugc uguauggaga acagggccaa     1560

ccuuggggua gguucggggc cgcauuaacc guacugggcg augucaacgg agacaaacua     1620

acagaugugg ccauuggcgc ucccggggag gaagacaauc guggagccgu uuaccucuuu     1680

cacgguacuu cuggcucagg gaucagucca agccauuccc agcggaucgc aggaucuaag     1740

cugucgccuc gacuucagua uuucggccag agcuuguccg gugggcagga ucugaccaug     1800

gacggccucg uggaucugac agucggagcg cagggccacg ugcuucuguu gagaucacag     1860

cccguacuca gggugaaagc uauuauggag uucaacccac gcgagguugc ccggaauguc     1920

uuugaaugca acgaccaagu ggugaagggg aaggaggcag gagaagucag aguuugucug     1980

cacgugcaga aaaguaccag ggaccgcuua cgagagggcc agauccaguc ugugguaacu     2040

uacgaucugg cccuagacag cggucggccc cauucccgug cugucuucaa ugagacgaag     2100

aacucaacaa gaaggcaaac ccaggugcuc gggcugacuc agaccugcga aacacuuaaa     2160

uugcagcugc cuaauugcau ugaggaucca guuagcccga uagugcuccg ccugaacuuu     2220

ucuuuagucg gaaccccucu guccgccuuc ggcaaccuuc ggccuguguu ggcagaagac     2280

gcucaaagac ucuuuacugc ccuguuccca uuugagaaga auugugguaa cgauaauauc     2340

ugccaggacg aucuaaguau uacauucagc uuuaugucuc uggacugucu cguugugggc     2400

gggcccaggg aguucaacgu aacggucacc gugcgaaaug auggagaaga cuccuaccgc     2460

acucagguga cauuuuucuu uccucuggau cuuucauauc ggaaagucag uaccuugcaa     2520

aaccagagaa gccagagguc guggcgucug gcgugcgagu ccgccucuag cacagaaguu     2580

ucaggcgcuu uaaagaguac uuccuguucu aucaaucacc caaucuuccc cgagaacagc     2640

gaagugaccu ucaauauuac guuugacgua gauuccaagg caucacucgg gaacaaacug     2700

cuucugaagg ccaaugugac cagcgagaac aauaugccgc gcacaaacaa aacugaguuc     2760

caguuggaac ucccugucaa guacgcugug uauaugguug ugaccaguca uggagucucu     2820

acaaaauacc ugaauuuuac ugccuccgag aacaccagcc gggugaugca acaccaguau     2880

cagguuucga accuaggcca gagaucacug ccaauaucuc ucguguuccu gguccccgua     2940

aggcuuaauc aaacggugau cugggaccga ccucagguua cauuuaguga aaacuugucc     3000

ucuaccugcc auacuaagga gcggcugccc agccacagcg acuucuuagc agaacuccgc     3060

aaggcgccag uggucaauug uuccauugcc gugugccaga gaauccagug ugauauuccc     3120

uuuuucggua uccaagagga auuuaacgcu acacugaaag ggaaucuuuc auucgacugg     3180

uacauaaaga ccagucacaa ccaucugcua aucguaagca cugccgagau ucucuuuaau     3240

gauucugugu ucacccuguu gcccggacag ggcgcauucg ucagguccca gacagagacg     3300

aaaguugaac cauuugaggu gccgaacccu cugcccuuaa ucguggguuc aagugucggc     3360

gggcuccugc uucuggcuuu gauuaccgcc gcacucuaua agcugggauu cuuuaaacgg     3420

caguacaagg acaugaugag cgaaggcggg ccacccggag ccgagccuca augaggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  1738
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt3)

<400>  1738
gggagaaagc uuaccauguu cagccugaag acccuccccu uucuucuguu guuacacgug       60

cagaucucca aagccuuccc ugucucuuca aaggagaaaa acacaaagac uguucaagac      120

uaccuggaaa aauuuuauca gcuaccaagu aaucaguacc agagcacgag aaagaacggc      180

accaauguga uuguagagaa gcucaaagaa augcaaaggu ucuuugggcu gaacgugaca      240

ggaaagccga augaggaaac ucuugauaug augaaaaagc cccggugcgg ugucccugac      300

uccggcgggu ucaugcugac cccaggaaac cccaaauggg agcgcacaaa uuugaccuau      360

cgaauacgua acuacacucc ucagcucucu gaggcugaag uggagagagc aaucaaggau      420

gccuuugaac uguggucggu ugcgucacca cugauuuuca caaggaucag ccagggcgag      480

gcugacauua auaucgccuu uuaucagcgg gaucauggug acaacagucc cuucgauggg      540

ccuaauggaa uacucgcaca cgccuuucaa ccaggccagg gcaucggggg agacgcucau      600

uucgaugcag aggaaaccug gacgaacacu uccgccaauu acaacuuauu ucugguggcu      660

gcccacgagu ucggucauuc ucuuggcuug gcgcacagcu ccgacccggg ggcacugaug      720

uaucccaauu acgccuuccg cgaaaccuca aacuacaguc uaccucagga ugacauugau      780

ggaauccagg cuauuuaugg ccucagcucu aacccaaucc aacccacagg uccuuccacu      840

ccaaagcccu gugacccguc acugaccuuu gacgccauaa caacccuuag aggggagauu      900

cuguucuuua aagauaggua cuucuggcgg cgccacccuc aguugcagcg agucgaaaug      960

aauuuuauca gccucuucug gcccagucug ccaacgggca uucaagcagc uuaugaggac     1020

uuugauagag acuuaaucuu ccuguuuaag ggaaaccagu acugggcccu cucuggcuau     1080

gauauccuuc agggguaccc uaaagacauu uccaauuaug gauuccccag cucggugcag     1140

gcgauagaug ccgcaguauu uuacaggucu aagacuuacu ucuuuguuaa cgaccaauuc     1200

uggcgguaug auaaucagcg ucaguucaug gagccagguu accccaaauc caucucaggc     1260

gcuuuuccug ggauugaaag uaagguggac gccgucuucc agcaagagca cuuuuuccau     1320

guguuuagcg gaccacgcua uuacgcuuuc gaucugaucg cccagagagu gacaaggguc     1380

gcacggggca acaaaugguu gaauugccga uaugguugag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  1739
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt3)

<400>  1739
gggagaaagc uuaccaugag ccuguggcag ccccucgugc uuguccuguu gguuuuaggc       60

ugcuguuucg ccgcuccuag acaaaggcag uccacccugg ugcuauuucc aggggaccuc      120

cggacaaacc ugacugaucg ccagcuugca gaggaauacc uguaucgaua cggauauacg      180

cguguagccg agaugagagg ugaaucuaaa ucauugggcc cggcgcuccu gcugcuccag      240

aaacaauuaa gucugcccga gaccggggaa cuugacagcg cuacauugaa ggccaugagg      300

acuccucggu gcggagugcc agaucugggc cgcuuccaga ccuuugaggg ugaccuaaaa      360

uggcaccauc acaauaucac auacuggauu cagaacuauu ccgaggaucu ccccagagca      420

gucauagacg augccuucgc uagggcauuu gcccuguggu cugcugugac cccucuuacu      480

uucacacggg uuuacucgcg cgacgccgau aucgugauuc aguuuggggu cgcggaacau      540

ggagacggcu auccauucga uggcaaggac gggcuguugg cacacgccuu ucccccugga      600

ccagguaucc aaggcgaugc ucauuucgac gacgaugagc ucuggucacu ggggaaagga      660

gugguaguuc cgacccgauu uggcaaugcc gacggugcag cuugucacuu ccccuuuauu      720

uucgaaggga gaagcuacag ugccugcacg acugauggaa gguccgacgg cuuaccuugg      780

uguucuacca cagcgaacua cgauacugac gaucgguucg gcuuuugccc aagcgagcgu      840

cuguauaccc aggacgggaa ugccgaugga aagcccuguc aguucccuuu uaucuuccag      900

ggucaauccu acucagcaug cacaaccgac ggccgcagug auggguauag auggugugcu      960

acgacugcca acuacgacag ggacaagcuc uuuggauucu gcccaacacg ggcugauagc     1020

accgugaugg gcgguaauuc ugccggggag cuuugugucu uucccuucac uuuucugggc     1080

aaagaauauu ccacaugcac cucagaggga cgaggcgacg ggcgcuugug gugcgcaacg     1140

accagcaacu ucgauaguga caagaaaugg ggauuuuguc cggaucaggg uuacucucua     1200

uuccuggugg ccgcucacga auuuggccau gcgcucgggc uggaccacuc cagcgugccu     1260

gaggcacuua uguaucccau guacagauuc acagaaggac caccucugca uaaggaugac     1320

gucaauggca uaaggcacuu guacgguccc cggccagagc ccgagccucg cccaccgacu     1380

accacaacuc cccagccuac cgccccaccc acaguuugcc cuaccgggcc acccacugug     1440

cacccgucgg aaagaccuac ggcuggccca acaggacccc cuucugccgg ccccaccggg     1500

ccaccuacug caggacccuc caccgccaca accguaccac ucucaccggu ggaugacgcu     1560

uguaacguca auaucuucga ugccauugca gagaucggua accaacugua uuuauuuaaa     1620

gacggcaagu acuggagguu cagugaaggg cguggaagcc ggccucaggg ccccuuucug     1680

auugcggaua aguggccagc ucuaccccga aaacucgacu ccguguucga ggaaagacug     1740

ucuaagaaau uguuuuucuu uagcgguagg cagguuuggg uguauacugg ggccucaguc     1800

cuuggcccuc gccggcugga caagcucgga cugggcgcag auguggccca gguaacaggg     1860

gcucuuagaa guggaagggg caaaaugcug uuguucuccg gucgccgacu cuggcgguuu     1920

gacguuaagg cccaaauggu ggauccacgu agcgcaucug aggucgacag aauguucccc     1980

ggggugccuc uggauacgca ugacgucuuu caguacaggg agaaggcuua uuucugccag     2040

gaucgcuuuu acuggcgggu gucaaguaga agcgaauuaa aucagguuga ccaaguggga     2100

uauguaaccu acgauauccu gcaguguccg gaggacugag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  1740
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt3)

<400>  1740
gggagaaagc uuaccaugca ccccggcgug cuggccgcuu uccucuuucu uagcuggacc       60

cauugcagag cacugccuuu gccauccggg ggagacgagg augacuuauc ugaagaggau      120

cugcaguucg ccgaaaggua ccuacgguca uauuaccacc cgacaaaccu cgcggguauc      180

cugaaggaga augcugccag uagcaugacu gaacgccuuc gagagaugca auccuuuuuc      240

ggccuggagg ucacggggaa auuggacgau aacacccucg acguuaugaa gaaaccccgu      300

uguggagugc cugauguagg cgaauauaau guguuuccaa gaacacugaa guggucuaaa      360

augaaccuga cuuacaggau ugucaauuau acccccgaca ugacacauuc ggagguggaa      420

aaggcauuca agaaagccuu uaagguuugg ucagauguga ccccucucaa cuucacucgg      480

uuacacgacg guauagcuga uaucaugauu agcuuuggga ucaaagagca uggagacuuc      540

uacccauuug auggccccag uggccugcuu gcacacgccu ucccuccagg gccgaauuau      600

ggaggugacg cucacuuuga cgaugacgag acauggaccu ccucuagcaa gggcuacaac      660

uuguuccugg ucgccgcgca ugaguucggg cacucccuag gacucgauca uucaaaagac      720

cccggcgcac ugauguuucc uauuuacacg uauacuggua agagucacuu caugcuucca      780

gaugacgaug ugcaggggau ccagagccug uacggacccg gcgacgaaga uccuaaucca      840

aagcacccca aaaccccgga caagugcgau ccuucuuugu cccucgacgc cauaacauca      900

cugcgcggcg aaacuaugau cuuuaaagac agauucuuuu ggagguuaca uccccagcaa      960

guagaugcug agcuguuccu caccaagagc uuuuggccag aacuuccuaa ccggauugac     1020

gccgcauaug agcaccccag ucaugaucug aucuucauuu uucgcgggcg aaaauucugg     1080

gcuuugaaug gauacgacau ccuagagggu uauccaaaga aaauaucuga acugggccuc     1140

cccaaggagg uuaagaaaau uuccgccgcg gugcacuuug aagauacagg gaagacccug     1200

cuuuucagcg gaaaccaggu cuggagauac gacgauacga aucauaucau ggacaaagau     1260

uauccuaggc ugauugagga agacuuucca ggcaucggug auaaggugga cgccguguac     1320

gagaaaaacg gguacaucua uuucuucaau ggcccgauuc aguuugagua cucgauaugg     1380

ucuaaccgga ucguccgugu uaugcccgca aacuccauuu ugugguguug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  1741
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt3)

<400>  1741
gggagaaagc uuaccaugga gacccccaac acaacugaag acuacgauac gaccacagag       60

uucgacuaug gcgaugccac uccuugccag aaggugaaug aaagagcuuu uggggcacaa      120

cugcucccac cgcuuuacag ccuggucuuc guuaucggau ugguggguaa cauuuuagua      180

gugcuggucc uagugcagua uaaaaggcuc aagaauauga ccuccauaua ccugcuuaac      240

cuggccaucu cugacuugcu cuuucuguuc acacugcccu uuuggauuga uuauaaacuc      300

aaggacgauu ggguuuucgg cgacgcgaug uguaaaaucu uaucaggguu uuacuauacc      360

ggacuguaca gugagauuuu cuuuaucaua cuuuugacua ucgaucggua ccuggcuauu      420

gugcacgccg ucuucgcacu acgcgcccga acagugaccu uuggcguaau cacgagcauu      480

aucauauggg cucucgcaau ucuggccucc augccugguc uuuauuucuc uaagacucag      540

ugggaauuua cccaucacac augcucgcug cauuucccac acgagucauu gcgugagugg      600

aaacucuucc aggcucugaa guuaaaucug uuugggcucg uucuuccccu guuggugaug      660

aucauuuguu acacuggaau caucaagauu cuacugagaa ggccuaacga gaaaaagagc      720

aaagccgucc ggcucauauu cgugaucaug auuaucuuuu uccuguuuug gaccccauau      780

aaucuuacaa uacugauuag uguguuccaa gacuuuuugu ucacccauga augcgaacag      840

ucccgccacc ucgaucuggc gguccagguu acggagguga ucgcauacac ucacuguugc      900

guaaaccccg ugaucuaugc cuuugucggc gagagauuca ggaaguacuu acggcagcug      960

uuucaucgcc gaguggcugu ucaccuagug aaguggcucc cuuuccuguc ugucgacaga     1020

cuugaaaggg ugagcuccac aucaccaagu accggcgagc augaauugag cgccggguuu     1080

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  1742
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt3)

<400>  1742
gggagaaagc uuaccaugag aacccuggcc ugccuccuuc uguugggaug uggguacuua       60

gcucacgugc uggcagagga agccgagauc cccagggaag ucauugagcg gcuagcgcgc      120

agccagauac auuccauccg agaccuccaa cgucugcuug aaauugauuc uguuggauca      180

gaggacaguc uggauacuag cuugagagcu cacggugugc augccacaaa gcacguaccu      240

gagaaaaggc cacucccgau ccggcgcaag agauccauug aagaggcagu gcccgccguc      300

ugcaaaacga ggaccgugau cuaugaaaua ccucggucuc agguugaccc aacaucggcu      360

aacuuccuga ucuggccccc uuguguggag gucaagcgcu gcacuggcug uugcaauacc      420

ucaagcguga aaugucagcc aagucgagua caucacagau ccguuaaggu ggcaaagguc      480

gaguacguga ggaaaaagcc caaacugaag gaagugcagg uccggcucga ggaacacuua      540

gagugcgccu gugcuacaac cucucugaac ccugauuauc gugaagagga cacugggcgc      600

ccaagagaga gcggcaaaaa gaggaagcgg aaacgacuua agccgacaug aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  1743
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt3)

<400>  1743
gggagaaagc uuaccaugaa cagaugcugg gcccuguucc ucagccuuug uugcuaccug       60

agguuggugu ccgcugaggg cgaccccauc ccugaagagu uauaugaaau gcugucugau      120

cacucaauuc ggaguuuuga cgaucuacag cgccuccugc auggggaccc aggagaggaa      180

gauggugcag agcuugaccu gaauaugacc cgaagccacu ccggcgggga guuggaaucu      240

cucgcccgug gaagaagguc gcugggcuca cugacaauag cggagccggc uaugaucgcc      300

gaauguaaga cucggacgga ggucuucgag auuagccgca gacucaucga uaggaccaac      360

gcaaacuuuu uaguuuggcc cccuugcgug gaaguacaac gguguagugg uugcuguaau      420

aaucgcaacg ugcagugccg accaacacag guccagcuga gacccgugca aguuaggaaa      480

auugagaucg ugcggaagaa accuauauuc aagaaagcca cugucacccu ugaagaccau      540

uuggcuugua agugcgagac aguggcagcc gcucguccag uaacccgcuc ccccggggga      600

ucucaggaac agagagccaa gacuccucag acaaggguua ccauccggac ggugcgaguc      660

cgcagaccac cgaaaggcaa gcacaggaaa uuuaagcaua cucacgauaa aaccgcgcug      720

aaggagacac uaggcgcaug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  1744
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt3)

<400>  1744
gggagaaagc uuaccaugag ccuguucggc cuccuucugu ugaccuccgc cuuagcuggg       60

cagagacaag gaacacaggc agagucuaac cugucaagua aguuucaguu cagcuccaau      120

aaagaacaga acggugugca agacccccag cacgagagga ucauuacugu cucuacgaau      180

ggcucgauac auucaccucg guuuccacac accuacccgc gcaacacagu ucuagugugg      240

cgacucguag ccguggaaga gaaugucugg auccagcuga cuuucgauga acguuuuggg      300

cuugaggacc ccgaggauga cauuugcaag uaugauuucg uggaaguuga ggaaccuagc      360

gacggaacca uccugggcag augguguggu agugggacag ugccaggaaa acagauuucc      420

aagggcaacc aaaucaggau acgguuuguc ucugaugagu acuuccccag cgagccuggc      480

uuuugcaucc auuauaauau ugugaugcca caguucaccg aagcgguauc ccccucaguu      540

uugccuccaa gugcucuccc gcuggaccug cucaacaaug ccaucacugc auuuagcaca      600

uuagaggauc ugauucgcua ccuugaaccc gagagauggc aguuggaccu ggaagaucua      660

uauaggccua ccuggcagcu ccuggggaaa gccuucgugu uuggacggaa gucucgcguc      720

guggaccuua accuguugac ggaggaggug cgacucuacu ccuguacucc aagaaauuuc      780

ucagucagca ucagggagga acugaagcgg accgauacaa uauucuggcc cgguugcuua      840

cugguuaaac guuguggcgg gaacugcgcu uguugccucc acaauuguaa cgaaugccaa      900

ugugugccua guaagguaac uaaaaaguau caugaggugc uucagcugcg cccaaaaacc      960

ggagucagag gcuugcacaa gucucuaaca gacguggcac uggaacacca ugaggagugc     1020

gacugcguuu guagggguuc caccggggga ugaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  1745
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt3)

<400>  1745
gggagaaagc uuaccaugca cagacugauc uucguguaca cccucauuug cgccaacuuu       60

uguagcugca gggacacauc cgcuacuccc cagucugcau caauaaaggc ccuucggaau      120

gcgaaccugc gccgagauga cuuguaucgu agagaugaga cgauccaagu caaaggaaau      180

ggguacguuc agaguccuag guucccaaac agcuauccgc ggaauuuacu gcuaaccugg      240

cgccuccauu cccaggaaaa cacaaggauu cagcuggugu uugacaauca auucggacuu      300

gaggaagcug agaacgauau cuguagauac gacuuuguag aaguggagga uauuucugag      360

acuucgacca ucauacgggg ucgcuggugc ggccacaagg aagugccccc ucgaaucaaa      420

ucaagaacaa aucagauuaa gaucaccuuc aaaagcgacg auuauuuugu cgccaagcca      480

ggguucaaga uuuacuauag ucuguuggag gacuuucagc ccgcagccgc uuccgaaacu      540

aacugggagu cuguuacaag cuccaucuca ggagugaguu acaauagccc uucugucacc      600

gauccaacgc ucauagcaga cgcccuggau aaaaagauug cugaguucga cacuguggaa      660

gaccugcuca aauacuuuaa ccccgagucc uggcaggaag auuuagagaa uauguaucug      720

gacaccccua gguaccgggg ccguucauau caugaucgca agagcaaagu agaccuugau      780

agauugaacg acgaugccaa gagguacagu uguacaccac ggaauuauuc uguuaacauc      840

cgagaggaac ugaagcuagc gaacgugguc uucuuuccgc gcugccuccu ggugcaaaga      900

ugugguggga auugcggaug uggcacugug aacuggaggu ccugcaccug uaauagcggc      960

aaaacaguca agaaauacca cgagguucuu caguucgaac ccgggcauau uaagcggcgc     1020

ggcagagcaa aaaccauggc ccugguggac auccaguugg aucaccacga gaggugcgac     1080

ugcaucuguu cgucucgucc uccacgguga ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  1746
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt3)

<400>  1746
gggagaaagc uuaccauggu gacccacagc aaguuccccg ccgcuggcau guccagaccu       60

cuggacacau cucucaggcu uaaaacuuuu ucaaguaaga gcgaguacca gcuggucguu      120

aacgcagugc ggaaauugca agaauccggg uucuauuggu cugccguaac gggaggugag      180

gcgaauuuac ugcuaucggc ugaaccagcc ggcaccuuuc ucauccgcga uucaagcgac      240

cagcgacauu ucuuuacacu gagugugaag acucaguccg ggaccaaaaa ccuucguauu      300

cagugcgagg gaggcucuuu cagccugcaa uccgauccga gaucaacaca gcccgucccu      360

agguuugacu guguguugaa gcucguucac cauuacaugc cacccccugg ugcaccaagu      420

uuccccagcc cuccaaccga accgucuucc gaggugcccg agcagccuuc agcccagcca      480

cugcccggga gcccuccacg gcgcgcuuau uacauauaua guggaggcga aaagaucccc      540

cugguccucu cuagaccguu auccagcaau guggcaacuc ugcaacaccu uugcaggaaa      600

acaguaaacg gccauuugga uucguacgag aagguuaccc agcugccugg gcccauucgg      660

gaauuucuag accaguauga ugccccacuc ugaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  1747
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt3)

<400>  1747
gggagaaagc uuaccauggu gcccagcgcc ggccagcugg cucucuucgc acuugggauc       60

guccuggccg cgugccaggc uuuggagaac uccaccucuc cuuuaucagc cgacccaccg      120

guugcagccg cugugguaag ucacuuuaau gauugucccg acagccauac acaauucugc      180

uuucacggaa cuuguagauu ccuggugcag gaagauaagc cugcaugcgu cugucauucc      240

gguuacgugg gcgccaggug cgagcacgcu gaccuacucg ccguuguggc ggcaucucag      300

aaaaagcaag ccauuacggc ucuggucgug guaucgauag uugcccuugc agugcugauc      360

auuaccugug ucuugaucca uugcugucag gugcggaaac acugcgaaug gugucgcgcu      420

cucauuugcc gacacgagaa gccaucagcc cugcugaaag ggcguacagc gugcugucau      480

agcgaaacug uggucugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  1748
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt3)

<400>  1748
gggagaaagc uuaccaugcc cccuagcggc cugagacucc uuccacuguu guuaccgcug       60

cuauggcucc uggugcuuac ccccgggagg ccugccgcug gacuguccac augcaagacu      120

aucgacaugg aguuggucaa acggaagcgc auugaagcaa uacgagguca gauccucucu      180

aaacugcguc uggccucacc acccagucaa ggcgagguuc cuccagggcc ccucccugaa      240

gcgguguuag cucuguacaa cagcacgaga gauaggguag ccggagaguc cgcagaacca      300

gagccggagc ccgaagccga cuauuacgcu aaggagguga cccggguccu uaugguggaa      360

acacacaaug agauuuauga uaaauucaag cagucuacuc auucgaucua cauguuuuuc      420

aacaccucag aguugcgcga agcaguuccu gagccagugc ugcuaagcag agccgaacuc      480

aggcugcuuc ggcugaaguu gaaagucgag cagcacgugg aacucuauca gaaguacagu      540

aauaacuccu ggcgcuaucu gucuaaucga uuacuggcuc ccagcgacuc cccugagugg      600

cucucauuug auguaacagg cguugugaga caauggcuua guaggggugg ggagauugaa      660

ggauuccggc ugagcgccca uuguucuugc gacucccgug auaacaccuu gcaggucgac      720

aucaauggcu uuacuacagg ccgcagaggg gaucuagcga ccauacacgg aaugaacagg      780

ccauuccugc uccugauggc aacgccccuu gagcgggccc agcaucugca gucaagccga      840

caccgcagag cuuuggacac uaauuacugu uuuaguucua ccgagaaaaa cugcugugug      900

aggcaacucu acaucgauuu ccggaaggac cuggguugga aauggauuca cgaaccgaag      960

ggcuaucaug ccaauuuuug cuuagggccu ugucccuaca ucuggucccu ggauacacag     1020

uauagcaagg ugcuagcacu cuacaaccag cacaauccag gagcuucggc cgcgccuugc     1080

uguguccccc aggcccugga accacuuccc auuguuuauu acgugggccg caaaccuaag     1140

guagagcaau ugucuaacau gaucgugaga uccugcaaau guucaugagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  1749
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt3)

<400>  1749
gggagaaagc uuaccaugca cuacugcgug cugagcgccu uccucauccu ucaucugguc       60

accguugcuu uguccuuauc uacauguuca acucuggaca uggaucaguu uaugagaaag      120

aggauugagg caauacgggg ccaaauccua aguaaacuca agcugacgag cccucccgaa      180

gacuauccag agccggaaga ggugcccccu gaaguaauuu ccaucuacaa cucuacccgc      240

gaucuucugc aggagaaagc cucgcgacgu gcggcugccu gcgagagaga aaggucagac      300

gaggaauauu acgcaaagga gguguauaaa auugauaugc cacccuucuu uccuagcgag      360

aaugccaucc cacccacauu cuaccggccu uauuuucgca uagucagauu cgacgugagu      420

gcuauggaaa agaacgcauc caauuugguu aaggccgagu uuaggguguu ccggcuccag      480

aacccaaaag cucgcguccc ggaacagcga aucgagcugu accaaauucu gaagucuaaa      540

gaucucacua gccccaccca gagauacauc gacuccaagg ugguaaaaac aagggccgaa      600

ggggaguggu uaucauuuga uguuaccgac gcggugcacg aguggcugca ucacaaggau      660

cggaaucuug gauucaagau uaguuugcau uguccuugcu guacuuuugu cccaagcaac      720

aauuauauca uacccaacaa aucugaggaa cuggaagcac guuucgccgg uauugacggc      780

acauccaccu acacgucagg ggaucagaag acuaucaaaa gcacccgcaa gaaaaauagu      840

ggaaagacac cucaccuacu ccugaugcuu cugccaucuu auagauugga gucccagcaa      900

acuaacaggc ggaaaaagcg agcucucgac gccgcauacu gcuuucgcaa ugugcaggac      960

aacuguugcc ugagacccuu auauauugau uucaagaggg accugggcug gaaauggauc     1020

cacgaaccga aggguuacaa ugcuaacuuc ugugccgggg cgugcccuua ucucuggagc     1080

ucggauaccc agcauucucg ggugcuuucc cuguacaaua caaucaaccc cgaggccuca     1140

gcaaguccau guugcgucag ccaggacuug gagccucuaa ccauucugua cuauauagga     1200

aaaacgccca agaucgaaca acucuccaac augauuguua aaucuugcaa guguagcuga     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  1750
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt3)

<400>  1750
gggagaaagc uuaccaugaa gaugcaucug cagagagccc ucgugguccu ugcucuguug       60

aacuucgcaa ccguuagcuu aucccugucu acaugcacua cgcuagacuu uggccacauc      120

aaaaagaaaa ggguggaggc cauucggggg caaauacucu caaagcugcg ccuuaccagu      180

cccccugaac caacaguaau gacucacgug ccguaccagg uccuggcguu guauaauagc      240

acccgagagc uccuggaaga gaugcaugga gaacgugagg aggguuguac acaggaaaac      300

accgaguccg aauacuaugc uaaagagauc cacaaguucg auaugauuca gggccuggcc      360

gagcauaaug aacucgcagu gugccccaag gggaucacuu cuaaaguuuu uagauucaac      420

gugucgucag ucgagaagaa uaggacaaac uuauuucggg ccgaguuccg cgugcugaga      480

guaccuaauc caagcaguaa aaggaacgaa caacggauug aacuuuuuca gaucuugcgc      540

cccgacgagc acauagcuaa gcagcgauac aucggaggca aaaaucugcc uaccagaggu      600

acggcagagu ggcuauccuu cgauguuacu gacaccguga gggaauggcu ccugcggcgu      660

gagucuaacc uugggcugga aauuagcauc cacuguccau gccauacauu ucagcccaau      720

ggagauauuu uggagaacau ccacgaaguc auggagauaa aguucaaggg cguggacaau      780

gaggaugacc auggccgcgg ggaucucgga agacugaaaa agcaaaaaga ccaccacaac      840

ccucauuuaa uucugaugau gaucccaccg cacaggcucg auaaucccgg ucagggcggg      900

cagcggaaga aacgagcccu ugacacuaac uauuguuuuc gcaaccugga agagaauugc      960

ugugugagac cuuuguacau ugauuucagg caggaccuag gauggaagug gguccaugaa     1020

ccaaaaggcu auuacgcuaa cuuuugcucc ggucccuguc cuuaccugcg gucagccgac     1080

accacacaca guaccguucu cgggcuguau aauacgcuua acccagaggc gagcgcaucu     1140

cccugcugug ugccgcaaga ucuggaaccu uugacuaucc ucuacuaugu aggacgcaca     1200

cccaaggugg agcagcuguc caauaugguc gugaagucau gcaaaugcag cugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  1751
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt3)

<400>  1751
gggagaaagc uuaccauggc ccccguggcu gucugggcag cccuggcggu uggccucgag       60

cuuugggcug ccgcacacgc ccugccugcu cagguggcau ucaccccaua cgccccggaa      120

cccgggagca caugcagauu gagggaguau uacgaccaaa cugcucagau guguugcucc      180

aaguguucuc cuggacagca ugccaaagua uuuugcacga agaccucaga uacagugugu      240

gacaguugcg aagauagcac uuauacccag uuauggaacu gggucccaga gugucugucc      300

ugcgguucuc gguguucguc agaccaagug gaaacacagg cgugcacccg cgagcagaau      360

cgaaucugua cuugccgucc cggcugguac ugcgcacuaa gcaaacagga gggguguaga      420

cucugcgccc cucugaggaa gugucggcca ggauucggcg uugcucgccc cgguacagaa      480

accagugaug uggucugcaa accuugugcc ccagggacgu uuuccaacac uaccucuagc      540

acagacauuu gcagaccgca ccaaauaugu aaugugguag caauccccgg aaacgcuucc      600

auggaugccg uuugcacuuc aaccaguccu acaaggagca uggcgccagg cgccgugcau      660

cuuccccagc cugucucuac ccggucccag cacacgcagc caacucccga gccgucaaca      720

gcaccuagca ccaguuuccu guugcccaug ggcccaucuc cucccgcuga aggguccacu      780

ggagacuuug cccucccagu gggucugauu gugggcguca cagcucuggg gcucuuaauc      840

auuggaguug ugaauugugu aaucaugacc caagugaaga agaaaccccu gugccuucag      900

cgcgaggcca aggucccuca uuugccagca gauaaagccc gaggcacgca ggguccggag      960

caacagcauc ugcuaauaac cgcucccagc ucgucuuccu caagucucga aagcuccgcg     1020

ucugcacugg acagaagggc cccuacacgg aaccagccac aggcucccgg gguggaggcc     1080

agcggagcag gcgaagcccg ugcuucaacu ggcaguuccg auagcucucc ugggggacac     1140

gguacccaag uuaaugugac auguaucguc aacgugugcu caaguagcga ccacuccucu     1200

cagugcucga gccaggccuc cucaacuaug ggcgauaccg acaguucucc aagcgagucc     1260

cccaaggacg aacagguacc guucucaaaa gaggagugug cauuucgcag ccaacuugaa     1320

acaccugaga cccuguuggg gucuacugaa gagaagccac ucccccuggg aguuccugau     1380

gcgggcauga agcccuccug aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  1752
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt3)

<400>  1752
gggagaaagc uuaccaugcc cgugaugaga cuguucccuu gcuuucucca gcuucuggcc       60

ggcuuggcuu uaccagcagu cccgccccaa cagugggccc ugagcgcggg gaacggaucc      120

ucugagguug aagugguacc uuuccaggag guguggggua ggucauacug ucgggcucua      180

gaacgccucg ucgacguggu uagugaguau ccaagcgaag uggagcacau guuuuccccc      240

ucuugcgucu cgcugcuucg auguaccggc ugcugugggg augagaaucu gcauugcgug      300

ccuguagaaa cagccaacgu uacuaugcag uugcucaaga uccguucagg agacagacca      360

agcuacgugg agcugacguu cagucaacac gucaggugug aaugccggcc ccugcgcgag      420

aaaaugaagc cugagagaag gcggccaaaa ggccgcggua agcgaagaag ggaaaaacag      480

cggccgaccg auugucaucu cugcggggac gcagugcccc gucgcugagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  1753
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt3)

<400>  1753
gggagaaagc uuaccaugac cgacagacag acagauacug cccccagccc uuccuaccau       60

cugcucccag gcaggcggcg cacgguggac gcugcagccu cucgagggca aggaccggag      120

cccgcgccug guggcggggu cgaaggaguu ggcgcucgug guguggcccu uaagcuguuc      180

guacaguugu uagggugcuc aagauuugga ggcgcagugg ucagggccgg cgaggcugaa      240

ccaagugggg cagcccggag cgcuuccucu ggacgcgagg aaccccagcc ugaggagggu      300

gaagaggaag aggagaaaga agaggaaaga ggcccacagu ggaggcuggg ggcccggaag      360

cccggaucgu ggaccggcga ggcggcagug ugugccgauu cagcuccugc cgcacgcgcu      420

ccacaagccc uagcgcgagc cagcgguaga gggggaaggg uugcacggcg uggcgcugaa      480

gagaguggcc cgccccacuc cccuucucgc agagggagcg ccuccagggc uggaccaggu      540

cgggccucag agacaaugaa cuuccuccug aguugggugc acuggagccu ugcacuguug      600

cucuaucugc aucacgccaa auggucucag gcugcgccca uggcagaagg cgggggacag      660

aaucaucacg aggucgugaa guuuauggac guauaccagc gauccuauug ccacccuauc      720

gaaacucugg uugauauuuu ccaagaguac ccagacgaaa uagaguauau cuuuaaaccc      780

ucaugugugc cgcucaugcg cugcggcggu uguugcaacg augagggguu agaauguguc      840

ccuaccgagg aaagcaauau uacaaugcag aucaugagaa uuaagcccca ucagggccag      900

cacaucggag agaugaguuu ccugcaacau aacaagugcg aauguaggcc uaaaaaggac      960

cgggcccgcc aggagaaaaa gucugugaga ggcaaaggga agggacagaa gaggaaacgu     1020

aagaaauccc gguacaagag cuggucggug uaugucggug cucgaugcug ucuuaugcca     1080

uggucuuugc ccggcccaca ccccugcggg ccuugcuccg agagaaggaa acaccuguuu     1140

guucaagauc cacagaccug uaagugcuca uguaaaaaua cugacagucg cugcaaggcc     1200

cggcagcuag aacucaacga gagaacaugu aggugcgaua agccgcgccg augaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  1754
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt3)

<400>  1754
gggagaaagc uuaccaugaa cuuccugcuc agcugggugc acuggucccu ugcccuguug       60

uuauaccugc aucacgcuaa guggucucag gcagccccca uggcggaggg cgggggacaa      120

aaucaucacg aagucguuaa auuuauggac guguaucaga gaucauacug ccauccuauc      180

gagacccuag uagauauuuu ccaggaauau ccagacgaga uagaauacau cuuuaagccg      240

aguugugugc cccucaugag gugcgguggc uguugcaacg augaggggcu ggaguguguc      300

ccuacagaag agagcaauau uacuaugcag aucaugcgga uuaaaccaca ccaaggacag      360

cacaucggcg aaauguccuu ccuucagcau aacaagugcg agugucgccc caaaaaggac      420

cgagcucguc aggagaagaa aucugugaga gguaagggga aaggacaaaa gaggaaacgg      480

aagaagucgc gcuauaaauc auggagcguu uacgugggcg ccagaugcug ucugaugccu      540

uggaguuugc caggccccca cccuugcggg ccauguuccg aaaggcggaa gcaucucuuu      600

guccaggauc cgcagacgug caaaugcucu uguaagaaua ccgacagccg cugcaaagca      660

cgacagcugg agcugaacga aagaacaugu aggugcgaua agccccggcg uugaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  1755
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt3)

<400>  1755
gggagaaagc uuaccaugag cccccugcuc agaaggcuuc uguuggccgc uuuacugcag       60

cuagccccug cacaagcgcc agugucccag ccggacgcuc ccggccacca gcggaagguc      120

guuucuugga ucgaugugua cacccgcgcc acaugccagc cucgagaggu agugguccca      180

cucacugugg aacugauggg gacgguugca aaacaacuug ugcccucaug ugucaccgug      240

cagcguugcg gagguuguug cccugacgau ggccuggagu guguaccaac agggcagcau      300

cagguuagaa ugcaaauuuu gaugauaagg uaucccagua gccagcucgg agaaaugucc      360

cuggaggaac acucucagug cgagugucgg ccuaagaaaa aggacucggc cgugaaacca      420

gaucgcgcug caacuccgca ucacagaccc cagccuaggu cagucccagg cugggacagc      480

gcccccggug cuccuagucc agccgauauc acccauccca caccggcgcc ugggcccucc      540

gcacacgccg cuccaucuac cacuagcgcc cugacaccug gacccgcagc ugccgcggcc      600

gacgcagcug ccuccucagu ggcuaagggc ggcgccugag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  1756
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt3)

<400>  1756
gggagaaagc uuaccaugca ccuucucggc uucuuuagcg uggccugcuc ccuucuggcu       60

gcagccuugu uacccgggcc uagagaggcg ccagcugccg cagccgcuuu cgaaucugga      120

cuggaccuau cagaugcaga gccggacgcc ggugaagcua ccgccuacgc gaguaaggau      180

cucgaggaac agcugaggag cgucuccucu guugacgagc uuaugacagu gcuguauccc      240

gaguacugga aaauguauaa gugucaauug cggaaaggcg gguggcagca uaaccgcgaa      300

caggcaaauc ucaacucgcg aacugaggaa acgaucaagu uugccgcugc ccacuacaau      360

accgagauuc ugaaaucaau agauaacgag uggcguaaga cacagugcau gccuagagaa      420

guauguaucg acgugggaaa ggaguucggc gucgcaacua auaccuuuuu caaaccaccc      480

ugcgugagcg uuuauaggug uggugggugc uguaacagug aaggacugca augcaugaau      540

acauccaccu cuuaccucag caagacuuua uuugagauua cagugccucu gucccagggc      600

ccaaaacccg ucaccaucuc auucgcuaac cauacgaguu gucggugcau gagcaagcug      660

gauguguauc gccagguaca cucuauuauc agaagguccu ugccugccac ucugccacag      720

ugucaagcgg ccaauaaaac cugcccgaca aacuacaugu ggaauaacca uauaugccgg      780

ugucuagcac aggaagacuu uauguucuca agcgaugcug gcgacgauag uacugacggg      840

uuucacgaua ucugcggacc caauaaggag cucgacgagg aaaccuguca gugcguuugu      900

cgcgccgguc ugcgaccugc uucuugcggc ccacacaagg agcuugacag aaacuccugu      960

cagugcgugu guaaaaauaa gcuguucccc agccaaugcg gggccaacag ggaauuugau     1020

gagaacacau gucagugcgu cugcaaacgg accuguccuc guaaucagcc auugaacccc     1080

ggaaagugcg caugugaaug cacggagucg ccgcaaaaau gucuccugaa gggcaaaaag     1140

uuccaucacc agacuugcuc uuguuaccgc agaccuugca caaauaggca gaaggccugu     1200

gagcccgguu ucuccuauuc agaagaggug ugccggugug ugccaaguua cuggaaacga     1260

ccucagauga gcugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  1757
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt3)

<400>  1757
gggagaaagc uuaccaugua cagagagugg guggucguua acguguucau gaugcuguau       60

guacagcucg ugcaaggcag cuccaaugaa cacgggcccg ucaagagguc uucacagagu      120

acccuugagc ggagcgaaca gcagauccgc gccgcuuccu cucuggagga auuguuacga      180

auuacacauu cggaggacug gaaacugugg cguugcagac uaaggcucaa gucauuuacu      240

agcauggaua gucgguccgc aucucaccgc agcacgagau ucgccgcgac cuuuuacgac      300

auagagacac ugaaagugau cgaugaagag uggcaaagga cucaguguuc cccucgggaa      360

accugcguug agguggcuuc agagcuugga aagaguacaa acaccuucuu uaaaccaccg      420

ugugucaaug uguuccgcug cgguggcugu ugcaacgaag agagccugau uuguaugaau      480

acuucuacau ccuauaucuc aaagcaguug uuugaaauua gcguaccccu caccaguguu      540

ccugagcugg ugccagucaa gguggccaac cauacggggu gcaaaugucu gcccacugca      600

ccucgacacc cauacucuau cauaagaagg uccauccaga uucccgaaga ggaccggugc      660

agccauucga agaaacucug uccuaucgau auguuauggg acucuaauaa gugcaaaugc      720

gugcugcaag aggaaaaccc acuugccgga accgaggauc acucccacuu gcaggaaccg      780

gcucugugug gcccccauau gauguucgac gaggaucguu gcgaaugugu cugcaagaca      840

ccuuguccaa aggaccuaau ucagcacccc aaaaauugcu cauguuuuga gugcaaggag      900

agucucgaaa cuuguugcca gaaacauaag cuguuccacc cugauaccug uagcugcgag      960

gaccgcugcc cauuucacac aagacccugu gcauccggua aaaccgccug cgcuaagcau     1020

uguagguucc cgaaagaaaa gcgggccgcg caagggccuc acucucgaaa gaaccccuga     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  1758
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt4)

<400>  1758
gggagaaagc uuaccaugga cagcgacgag accggcuucg agcacagcgg ccugugggug       60

agcgugcugg ccggccugcu gcugggcgcc ugccaggccc accccauccc cgacagcagc      120

ccccugcugc aguucggcgg ccaggugaga cagagauacc uguacaccga cgacgcccag      180

cagaccgagg cccaccugga gaucagagag gacggcaccg ugggcggcgc cgccgaccag      240

agccccgaga gccugcugca gcugaaggcc cugaagcccg gcgugaucca gauccugggc      300

gugaagacca gcagauuccu gugccagaga cccgacggcg cccuguacgg cagccugcac      360

uucgaccccg aggccugcag cuucagagag cugcugcugg aggacggcua caacguguac      420

cagagcgagg cccacggccu gccccugcac cugcccggca acaagagccc ccacagagac      480

cccgccccca gaggccccgc cagauuccug ccccugcccg gccugccccc cgcccugccc      540

gagccccccg gcauccuggc cccccagccc cccgacgugg gcagcagcga cccccugagc      600

auggugggcc ccagccaggg cagaagcccc agcuacgcca gcugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  1759
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt4)

<400>  1759
gggagaaagc uuaccaugca cagcuucccc ccccugcugc ugcugcuguu cuggggcgug       60

gugagccaca gcuuccccgc cacccuggag acccaggagc aggacgugga ccuggugcag      120

aaguaccugg agaaguacua caaccugaag aacgacggca gacaggugga gaagagaaga      180

aacagcggcc ccguggugga gaagcugaag cagaugcagg aguucuucgg ccugaaggug      240

accggcaagc ccgacgccga gacccugaag gugaugaagc agcccagaug cggcgugccc      300

gacguggccc aguucgugcu gaccgagggc aaccccagau gggagcagac ccaccugacc      360

uacagaaucg agaacuacac ccccgaccug cccagagccg acguggacca cgccaucgag      420

aaggccuucc agcuguggag caacgugacc ccccugaccu ucaccaaggu gagcgagggc      480

caggccgaca ucaugaucag cuucgugaga ggcgaccaca gagacaacag ccccuucgac      540

ggccccggcg gcaaccuggc ccacgccuuc cagcccggcc ccggcaucgg cggcgacgcc      600

cacuucgacg aggacgagag auggaccaac aacuucagag aguacaaccu gcacagagug      660

gccgcccacg agcugggcca cagccugggc cugagccaca gcaccgacau cggcgcccug      720

auguacccca gcuacaccuu cagcggcgac gugcagcugg cccaggacga caucgacggc      780

auccaggcca ucuacggcag aagccagaac cccgugcagc ccaucggccc ccagaccccc      840

aaggccugcg acagcaagcu gaccuucgac gccaucacca ccaucagagg cgaggugaug      900

uucuucaagg acagauucua caugagaacc aaccccuucu accccgaggu ggagcugaac      960

uucaucagcg uguucuggcc ccagcugccc aacggccugg aggccgccua cgaguucgcc     1020

gacagagacg aggugagauu cuucaagggc aacaaguacu gggccgugca gggccagaac     1080

gugcugcacg gcuaccccaa ggacaucuac agcagcuucg gcuuccccag aaccgugaag     1140

cacaucgacg ccgcccugag cgaggagaac accggcaaga ccuacuucuu cguggccaac     1200

aaguacugga gauacgacga guacaagaga agcauggacc ccggcuaccc caagaugauc     1260

gcccacgacu uccccggcau cggccacaag guggacgccg uguucaugaa ggacggcuuc     1320

uucuacuucu uccacggcac cagacaguac aaguucgacc ccaagaccaa gagaauccug     1380

acccugcaga aggccaacag cugguucaac ugcagaaaga acugaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  1760
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt4)

<400>  1760
gggagaaagc uuaccaugca cagcuucccc ccccugcugc ugcugcuguu cuggggcgug       60

gugagccaca gcuucgugcu gaccgagggc aaccccagau gggagcagac ccaccugacc      120

uacagaaucg agaacuacac ccccgaccug cccagagccg acguggacca cgccaucgag      180

aaggccuucc agcuguggag caacgugacc ccccugaccu ucaccaaggu gagcgagggc      240

caggccgaca ucaugaucag cuucgugaga ggcgaccaca gagacaacag ccccuucgac      300

ggccccggcg gcaaccuggc ccacgccuuc cagcccggcc ccggcaucgg cggcgacgcc      360

cacuucgacg aggacgagag auggaccaac aacuucagag aguacaaccu gcacagagug      420

gccgcccacg agcugggcca cagccugggc cugagccaca gcaccgacau cggcgcccug      480

auguacccca gcuacaccuu cagcggcgac gugcagcugg cccaggacga caucgacggc      540

auccaggcca ucuacggcag aagccagaac cccgugcagc ccaucggccc ccagaccccc      600

aaggccugcg acagcaagcu gaccuucgac gccaucacca ccaucagagg cgaggugaug      660

uucuucaagg acagauucua caugagaacc aaccccuucu accccgaggu ggagcugaac      720

uucaucagcg uguucuggcc ccagcugccc aacggccugg aggccgccua cgaguucgcc      780

gacagagacg aggugagauu cuucaagggc aacaaguacu gggccgugca gggccagaac      840

gugcugcacg gcuaccccaa ggacaucuac agcagcuucg gcuuccccag aaccgugaag      900

cacaucgacg ccgcccugag cgaggagaac accggcaaga ccuacuucuu cguggccaac      960

aaguacugga gauacgacga guacaagaga agcauggacc ccggcuaccc caagaugauc     1020

gcccacgacu uccccggcau cggccacaag guggacgccg uguucaugaa ggacggcuuc     1080

uucuacuucu uccacggcac cagacaguac aaguucgacc ccaagaccaa gagaauccug     1140

acccugcaga aggccaacag cugguucaac ugcagaaaga acugaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  1761
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt4)

<400>  1761
gggagaaagc uuaccaugaa gaagaacauc cugaagaucc ugauggacag cuacagcaag       60

gagagcaaga uccagaccgu gagaagagug accagcguga gccugcuggc cguguaccug      120

accaugaaca ccagcagccu ggugcuggcc aagcccaucg agaacaccaa cgacaccagc      180

aucaagaacg uggagaagcu gagaaacgcc cccaacgagg agaacagcaa gaagguggag      240

gacagcaaga acgacaaggu ggagcacgug aagaacaucg aggaggccaa gguggagcag      300

guggcccccg aggugaagag caagagcacc cugagaagcg ccagcaucgc caacaccaac      360

agcgagaagu acgacuucga guaccugaac ggccugagcu acaccgagcu gaccaaccug      420

aucaagaaca ucaaguggaa ccagaucaac ggccuguuca acuacagcac cggcagccag      480

aaguucuucg gcgacaagaa cagagugcag gccaucauca acgcccugca ggagagcggc      540

agaaccuaca ccgccaacga caugaagggc aucgagaccu ucaccgaggu gcugagagcc      600

ggcuucuacc ugggcuacua caacgacggc cugagcuacc ugaacgacag aaacuuccag      660

gacaagugca uccccgccau gaucgccauc cagaagaacc ccaacuucaa gcugggcacc      720

gccgugcagg acgaggugau caccagccug ggcaagcuga ucggcaacgc cagcgccaac      780

gccgaggugg ugaacaacug cgugcccgug cugaagcagu ucagagagaa ccugaaccag      840

uacgcccccg acuacgugaa gggcaccgcc gugaacgagc ugaucaaggg caucgaguuc      900

gacuucagcg gcgccgccua cgagaaggac gugaagacca ugcccuggua cggcaagauc      960

gaccccuuca ucaacgagcu gaaggcccug ggccuguacg gcaacaucac cagcgccacc     1020

gagugggcca gcgacguggg caucuacuac cugagcaagu ucggccugua cagcaccaac     1080

agaaacgaca ucgugcagag ccuggagaag gccguggaca uguacaagua cggcaagauc     1140

gccuucgugg ccauggagag aaucaccugg gacuacgacg gcaucggcag caacggcaag     1200

aagguggacc acgacaaguu ccuggacgac gccgagaagc acuaccugcc caagaccuac     1260

accuucgaca acggcaccuu caucaucaga gccggcgaca aggugagcga ggagaagauc     1320

aagagacugu acugggccag cagagaggug aagagccagu uccacagagu ggugggcaac     1380

gacaaggccc uggagguggg caacgccgac gacgugcuga ccaugaagau cuucaacagc     1440

cccgaggagu acaaguucaa caccaacauc aacggcguga gcaccgacaa cggcggccug     1500

uacaucgagc ccagaggcac cuucuacacc uacgagagaa ccccccagca gagcaucuuc     1560

agccuggagg agcuguucag acacgaguac acccacuacc ugcaggccag auaccuggug     1620

gacggccugu ggggccaggg ccccuucuac gagaagaaca gacugaccug guucgacgag     1680

ggcaccgccg aguucuucgc cggcagcacc agaaccagcg gcgugcugcc cagaaagagc     1740

auccugggcu accuggccaa ggacaaggug gaccacagau acagccugaa gaagacccug     1800

aacagcggcu acgacgacag cgacuggaug uucuacaacu acggcuucgc cguggcccac     1860

uaccuguacg agaaggacau gcccaccuuc aucaagauga acaaggccau ccugaacacc     1920

gacgugaaga gcuacgacga gaucaucaag aagcugagcg acgacgccaa caagaacacc     1980

gaguaccaga accacaucca ggagcuggcc gacaaguacc agggcgccgg caucccccug     2040

gugagcgacg acuaccugaa ggaccacggc uacaagaagg ccagcgaggu guacagcgag     2100

aucagcaagg ccgccagccu gaccaacacc agcgugaccg ccgagaagag ccaguacuuc     2160

aacaccuuca cccugagagg caccuacacc ggcgagacca gcaagggcga guucaaggac     2220

ugggacgaga ugagcaagaa gcuggacggc acccuggaga gccuggccaa gaacagcugg     2280

agcggcuaca agacccugac cgccuacuuc accaacuaca gagugaccag cgacaacaag     2340

gugcaguacg acgugguguu ccacggcgug cugaccgaca acgccgacau cagcaacaac     2400

aaggccccca ucgccaaggu gaccggcccc agcaccggcg ccgugggcag aaacaucgag     2460

uucagcggca aggacagcaa ggacgaggac ggcaagaucg ugagcuacga cugggacuuc     2520

ggcgacggcg ccaccagcag aggcaagaac agcgugcacg ccuacaagaa ggccggcacc     2580

uacaacguga cccugaaggu gaccgacgac aagggcgcca ccgccaccga gagcuucacc     2640

aucgagauca agaacgagga caccaccacc cccaucacca aggagaugga gcccaacgac     2700

gacaucaagg aggccaacgg ccccaucgug gagggcguga ccgugaaggg cgaccugaac     2760

ggcagcgacg acgccgacac cuucuacuuc gacgugaagg aggacggcga cgugaccauc     2820

gagcugcccu acagcggcag cagcaacuuc accuggcugg uguacaagga gggcgacgac     2880

cagaaccaca ucgccagcgg caucgacaag aacaacagca aggugggcac cuucaagagc     2940

accaagggca gacacuacgu guucaucuac aagcacgaca gcgccagcaa caucagcuac     3000

agccugaaca ucaagggccu gggcaacgag aagcugaagg agaaggagaa caacgacagc     3060

agcgacaagg ccaccgugau ccccaacuuc aacaccacca ugcagggcag ccugcugggc     3120

gacgacagca gagacuacua cagcuucgag gugaaggagg agggcgaggu gaacaucgag     3180

cuggacaaga aggacgaguu cggcgugacc uggacccugc accccgagag caacaucaac     3240

gacagaauca ccuacggcca gguggacggc aacaagguga gcaacaaggu gaagcugaga     3300

cccggcaagu acuaccugcu gguguacaag uacagcggca gcggcaacua cgagcugaga     3360

gugaacaagu gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  1762
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt4)

<400>  1762
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcuguuccu guucagcagc       60

gccuacagca ucgccaacac caacagcgag aaguacgacu ucgaguaccu gaacggccug      120

agcuacaccg agcugaccaa ccugaucaag aacaucaagu ggaaccagau caacggccug      180

uucaacuaca gcaccggcag ccagaaguuc uucggcgaca agaacagagu gcaggccauc      240

aucaacgccc ugcaggagag cggcagaacc uacaccgcca acgacaugaa gggcaucgag      300

accuucaccg aggugcugag agccggcuuc uaccugggcu acuacaacga cggccugagc      360

uaccugaacg acagaaacuu ccaggacaag ugcauccccg ccaugaucgc cauccagaag      420

aaccccaacu ucaagcuggg caccgccgug caggacgagg ugaucaccag ccugggcaag      480

cugaucggca acgccagcgc caacgccgag guggugaaca acugcgugcc cgugcugaag      540

caguucagag agaaccugaa ccaguacgcc cccgacuacg ugaagggcac cgccgugaac      600

gagcugauca agggcaucga guucgacuuc agcggcgccg ccuacgagaa ggacgugaag      660

accaugcccu gguacggcaa gaucgacccc uucaucaacg agcugaaggc ccugggccug      720

uacggcaaca ucaccagcgc caccgagugg gccagcgacg ugggcaucua cuaccugagc      780

aaguucggcc uguacagcac caacagaaac gacaucgugc agagccugga gaaggccgug      840

gacauguaca aguacggcaa gaucgccuuc guggccaugg agagaaucac cugggacuac      900

gacggcaucg gcagcaacgg caagaaggug gaccacgaca aguuccugga cgacgccgag      960

aagcacuacc ugcccaagac cuacaccuuc gacaacggca ccuucaucau cagagccggc     1020

gacaagguga gcgaggagaa gaucaagaga cuguacuggg ccagcagaga ggugaagagc     1080

caguuccaca gagugguggg caacgacaag gcccuggagg ugggcaacgc cgacgacgug     1140

cugaccauga agaucuucaa cagccccgag gaguacaagu ucaacaccaa caucaacggc     1200

gugagcaccg acaacggcgg ccuguacauc gagcccagag gcaccuucua caccuacgag     1260

agaacccccc agcagagcau cuucagccug gaggagcugu ucagacacga guacacccac     1320

uaccugcagg ccagauaccu gguggacggc cuguggggcc agggccccuu cuacgagaag     1380

aacagacuga ccugguucga cgagggcacc gccgaguucu ucgccggcag caccagaacc     1440

agcggcgugc ugcccagaaa gagcauccug ggcuaccugg ccaaggacaa gguggaccac     1500

agauacagcc ugaagaagac ccugaacagc ggcuacgacg acagcgacug gauguucuac     1560

aacuacggcu ucgccguggc ccacuaccug uacgagaagg acaugcccac cuucaucaag     1620

augaacaagg ccauccugaa caccgacgug aagagcuacg acgagaucau caagaagcug     1680

agcgacgacg ccaacaagaa caccgaguac cagaaccaca uccaggagcu ggccgacaag     1740

uaccagggcg ccggcauccc ccuggugagc gacgacuacc ugaaggacca cggcuacaag     1800

aaggccagcg agguguacag cgagaucagc aaggccgcca gccugaccaa caccagcgug     1860

accgccgaga agagccagua cuucaacacc uucacccuga gaggcaccua caccggcgag     1920

accagcaagg gcgaguucaa ggacugggac gagaugagca agaagcugga cggcacccug     1980

gagagccugg ccaagaacag cuggagcggc uacaagaccc ugaccgccua cuucaccaac     2040

uacagaguga ccagcgacaa caaggugcag uacgacgugg uguuccacgg cgugcugacc     2100

gacaacgccg acaucagcaa caacaaggcc cccaucgcca aggugaccgg ccccagcacc     2160

ggcgccgugg gcagaaacau cgaguucagc ggcaaggaca gcaaggacga ggacggcaag     2220

aucgugagcu acgacuggga cuucggcgac ggcgccacca gcagaggcaa gaacagcgug     2280

cacgccuaca agaaggccgg caccuacaac gugacccuga aggugaccga cgacaagggc     2340

gccaccgcca ccgagagcuu caccaucgag aucaagaacg aggacaccac cacccccauc     2400

accaaggaga uggagcccaa cgacgacauc aaggaggcca acggccccau cguggagggc     2460

gugaccguga agggcgaccu gaacggcagc gacgacgccg acaccuucua cuucgacgug     2520

aaggaggacg gcgacgugac caucgagcug cccuacagcg gcagcagcaa cuucaccugg     2580

cugguguaca aggagggcga cgaccagaac cacaucgcca gcggcaucga caagaacaac     2640

agcaaggugg gcaccuucaa gagcaccaag ggcagacacu acguguucau cuacaagcac     2700

gacagcgcca gcaacaucag cuacagccug aacaucaagg gccugggcaa cgagaagcug     2760

aaggagaagg agaacaacga cagcagcgac aaggccaccg ugauccccaa cuucaacacc     2820

accaugcagg gcagccugcu gggcgacgac agcagagacu acuacagcuu cgaggugaag     2880

gaggagggcg aggugaacau cgagcuggac aagaaggacg aguucggcgu gaccuggacc     2940

cugcaccccg agagcaacau caacgacaga aucaccuacg gccaggugga cggcaacaag     3000

gugagcaaca aggugaagcu gagacccggc aaguacuacc ugcuggugua caaguacagc     3060

ggcagcggca acuacgagcu gagagugaac aagugaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  1763
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt4)

<400>  1763
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcuguuccu guucagcagc       60

gccuacagca ugaagaagaa cauccugaag auccugaugg acagcuacag caaggagagc      120

aagauccaga ccgugagaag agugaccagc gugagccugc uggccgugua ccugaccaug      180

aacaccagca gccuggugcu ggccaagccc aucgagaaca ccaacgacac cagcaucaag      240

aacguggaga agcugagaaa cgcccccaac gaggagaaca gcaagaaggu ggaggacagc      300

aagaacgaca agguggagca cgugaagaac aucgaggagg ccaaggugga gcagguggcc      360

cccgagguga agagcaagag cacccugaga agcgccagca gaagaagaag aaagagaauc      420

gccaacacca acagcgagaa guacgacuuc gaguaccuga acggccugag cuacaccgag      480

cugaccaacc ugaucaagaa caucaagugg aaccagauca acggccuguu caacuacagc      540

accggcagcc agaaguucuu cggcgacaag aacagagugc aggccaucau caacgcccug      600

caggagagcg gcagaaccua caccgccaac gacaugaagg gcaucgagac cuucaccgag      660

gugcugagag ccggcuucua ccugggcuac uacaacgacg gccugagcua ccugaacgac      720

agaaacuucc aggacaagug cauccccgcc augaucgcca uccagaagaa ccccaacuuc      780

aagcugggca ccgccgugca ggacgaggug aucaccagcc ugggcaagcu gaucggcaac      840

gccagcgcca acgccgaggu ggugaacaac ugcgugcccg ugcugaagca guucagagag      900

aaccugaacc aguacgcccc cgacuacgug aagggcaccg ccgugaacga gcugaucaag      960

ggcaucgagu ucgacuucag cggcgccgcc uacgagaagg acgugaagac caugcccugg     1020

uacggcaaga ucgaccccuu caucaacgag cugaaggccc ugggccugua cggcaacauc     1080

accagcgcca ccgagugggc cagcgacgug ggcaucuacu accugagcaa guucggccug     1140

uacagcacca acagaaacga caucgugcag agccuggaga aggccgugga cauguacaag     1200

uacggcaaga ucgccuucgu ggccauggag agaaucaccu gggacuacga cggcaucggc     1260

agcaacggca agaaggugga ccacgacaag uuccuggacg acgccgagaa gcacuaccug     1320

cccaagaccu acaccuucga caacggcacc uucaucauca gagccggcga caaggugagc     1380

gaggagaaga ucaagagacu guacugggcc agcagagagg ugaagagcca guuccacaga     1440

guggugggca acgacaaggc ccuggaggug ggcaacgccg acgacgugcu gaccaugaag     1500

aucuucaaca gccccgagga guacaaguuc aacaccaaca ucaacggcgu gagcaccgac     1560

aacggcggcc uguacaucga gcccagaggc accuucuaca ccuacgagag aaccccccag     1620

cagagcaucu ucagccugga ggagcuguuc agacacgagu acacccacua ccugcaggcc     1680

agauaccugg uggacggccu guggggccag ggccccuucu acgagaagaa cagacugacc     1740

ugguucgacg agggcaccgc cgaguucuuc gccggcagca ccagaaccag cggcgugcug     1800

cccagaaaga gcauccuggg cuaccuggcc aaggacaagg uggaccacag auacagccug     1860

aagaagaccc ugaacagcgg cuacgacgac agcgacugga uguucuacaa cuacggcuuc     1920

gccguggccc acuaccugua cgagaaggac augcccaccu ucaucaagau gaacaaggcc     1980

auccugaaca ccgacgugaa gagcuacgac gagaucauca agaagcugag cgacgacgcc     2040

aacaagaaca ccgaguacca gaaccacauc caggagcugg ccgacaagua ccagggcgcc     2100

ggcauccccc uggugagcga cgacuaccug aaggaccacg gcuacaagaa ggccagcgag     2160

guguacagcg agaucagcaa ggccgccagc cugaccaaca ccagcgugac cgccgagaag     2220

agccaguacu ucaacaccuu cacccugaga ggcaccuaca ccggcgagac cagcaagggc     2280

gaguucaagg acugggacga gaugagcaag aagcuggacg gcacccugga gagccuggcc     2340

aagaacagcu ggagcggcua caagacccug accgccuacu ucaccaacua cagagugacc     2400

agcgacaaca aggugcagua cgacguggug uuccacggcg ugcugaccga caacgccgac     2460

aucagcaaca acaaggcccc caucgccaag gugaccggcc ccagcaccgg cgccgugggc     2520

agaaacaucg aguucagcgg caaggacagc aaggacgagg acggcaagau cgugagcuac     2580

gacugggacu ucggcgacgg cgccaccagc agaggcaaga acagcgugca cgccuacaag     2640

aaggccggca ccuacaacgu gacccugaag gugaccgacg acaagggcgc caccgccacc     2700

gagagcuuca ccaucgagau caagaacgag gacaccacca cccccaucac caaggagaug     2760

gagcccaacg acgacaucaa ggaggccaac ggccccaucg uggagggcgu gaccgugaag     2820

ggcgaccuga acggcagcga cgacgccgac accuucuacu ucgacgugaa ggaggacggc     2880

gacgugacca ucgagcugcc cuacagcggc agcagcaacu ucaccuggcu gguguacaag     2940

gagggcgacg accagaacca caucgccagc ggcaucgaca agaacaacag caaggugggc     3000

accuucaaga gcaccaaggg cagacacuac guguucaucu acaagcacga cagcgccagc     3060

aacaucagcu acagccugaa caucaagggc cugggcaacg agaagcugaa ggagaaggag     3120

aacaacgaca gcagcgacaa ggccaccgug auccccaacu ucaacaccac caugcagggc     3180

agccugcugg gcgacgacag cagagacuac uacagcuucg aggugaagga ggagggcgag     3240

gugaacaucg agcuggacaa gaaggacgag uucggcguga ccuggacccu gcaccccgag     3300

agcaacauca acgacagaau caccuacggc cagguggacg gcaacaaggu gagcaacaag     3360

gugaagcuga gacccggcaa guacuaccug cugguguaca aguacagcgg cagcggcaac     3420

uacgagcuga gagugaacaa gugaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  1764
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt4)

<400>  1764
gggagaaagc uuaccaugaa cuuccugaag aucauccuga acagaggcaa gaccaugaag       60

agaaagugcc ugagcaagag acugaugcug gccaucacca uggccaccau cuucaccgug      120

aacagcaccc ugcccaucua cgccgccgug gacaagaaca acgccaccgc cgccgugcag      180

aacgagagca agagauacac cgugagcuac cugaagaccc ugaacuacua cgaccuggug      240

gaccugcugg ugaagaccga gaucgagaac cugcccgacc uguuccagua cagcagcgac      300

gccaaggagu ucuacggcaa caagaccaga augagcuuca ucauggacga gaucggcaga      360

agagcccccc aguacaccga gaucgaccac aagggcaucc ccacccuggu ggagguggug      420

agagccggcu ucuaccuggg cuuccacaac aaggagcuga acgagaucaa caagagaagc      480

uucaaggaga gagugauccc cagcauccug gccauccaga agaaccccaa cuucaagcug      540

ggcaccgagg ugcaggacaa gaucgugagc gccaccggcc ugcuggccgg caacgagacc      600

gccccccccg agguggugaa caacuucacc cccauccugc aggacugcau caagaacauc      660

gacagauacg cccuggacga ccugaagagc aaggcccugu ucaacgugcu ggccgccccc      720

accuacgaca ucaccgagua ccugagagcc accaaggaga agcccgagaa cacccccugg      780

uacggcaaga ucgacggcuu caucaacgag cugaagaagc uggcccugua cggcaagauc      840

aacgacaaca acagcuggau caucgacaac ggcaucuacc acaucgcccc ccugggcaag      900

cugcacagca acaacaagau cggcaucgag acccugaccg aggugaugaa gguguacccc      960

uaccugagca ugcagcaccu gcagagcgcc gaccagauca agagacacua cgacagcaag     1020

gacgccgagg gcaacaagau cccccuggac aaguucaaga aggagggcaa ggagaaguac     1080

ugccccaaga ccuacaccuu cgacgacggc aaggugauca ucaaggccgg cgccagagug     1140

gaggaggaga aggugaagag acuguacugg gccagcaagg aggugaacag ccaguucuuc     1200

agaguguacg gcaucgacaa gccccuggag gagggcaacc ccgacgacau ccugaccaug     1260

gugaucuaca acagccccga ggaguacaag cugaacagcg ugcuguacgg cuacgacacc     1320

aacaacggcg gcauguacau cgagcccgag ggcaccuucu ucaccuacga gagagaggcc     1380

caggagagca ccuacacccu ggaggagcug uucagacacg aguacaccca cuaccugcag     1440

ggcagauacg ccgugcccgg ccaguggggc agaaccaagc uguacgacaa cgacagacug     1500

accugguacg aggagggcgg cgccgagcug uucgccggca gcaccagaac cagcggcauc     1560

cugcccagaa agagcaucgu gagcaacauc cacaacacca ccagaaacaa cagauacaag     1620

cugagcgaca ccgugcacag caaguacggc gccagcuucg aguucuacaa cuacgccugc     1680

auguucaugg acuacaugua caacaaggac augggcaucc ugaacaagcu gaacgaccug     1740

gccaagaaca acgacgugga cggcuacgac aacuacauca gagaccugag cagcaacuac     1800

gcccugaacg acaaguacca ggaccacaug caggagagaa ucgacaacua cgagaaccug     1860

accgugcccu ucguggccga cgacuaccug gugagacacg ccuacaagaa ccccaacgag     1920

aucuacagcg agaucagcga gguggccaag cugaaggacg ccaagagcga ggugaagaag     1980

agccaguacu ucagcaccuu cacccugaga ggcagcuaca ccggcggcgc cagcaagggc     2040

aagcuggagg accagaaggc caugaacaag uucaucgacg acagccugaa gaagcuggac     2100

accuacagcu ggagcggcua caagacccug accgccuacu ucaccaacua caagguggac     2160

agcagcaaca gagugaccua cgacguggug uuccacggcu accugcccaa cgagggcgac     2220

agcaagaaca gccugcccua cggcaagauc aacggcaccu acaagggcac cgagaaggag     2280

aagaucaagu ucagcagcga gggcagcuuc gaccccgacg gcaagaucgu gagcuacgag     2340

ugggacuucg gcgacggcaa caagagcaac gaggagaacc ccgagcacag cuacgacaag     2400

gugggcaccu acaccgugaa gcugaaggug accgacgaca agggcgagag cagcgugagc     2460

accaccaccg ccgagaucaa ggaccugagc gagaacaagc ugcccgugau cuacaugcac     2520

gugcccaaga gcggcgcccu gaaccagaag gugguguucu acggcaaggg caccuacgac     2580

cccgacggca gcaucgccgg cuaccagugg gacuucggcg acggcagcga cuucagcagc     2640

gagcagaacc ccagccacgu guacaccaag aagggcgagu acaccgugac ccugagagug     2700

auggacagca gcggccagau gagcgagaag accaugaaga ucaagaucac cgaccccgug     2760

uaccccaucg gcaccgagaa ggagcccaac aacagcaagg agaccgccag cggccccauc     2820

gugcccggca uccccgugag cggcaccauc gagaacacca gcgaccagga cuacuucuac     2880

uucgacguga ucacccccgg cgaggugaag aucgacauca acaagcuggg cuacggcggc     2940

gccaccuggg ugguguacga cgagaacaac aacgccguga gcuacgccac cgacgacggc     3000

cagaaccuga gcggcaaguu caaggccgac aagcccggca gauacuacau ccaccuguac     3060

auguucaacg gcagcuacau gcccuacaga aucaacaucg agggcagcgu gggcagauga     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  1765
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt4)

<400>  1765
gggagaaagc uuaccaugaa gagaaagugc cugagcaaga gacugaugcu ggccaucacc       60

auggccacca ucuucaccgu gaacagcacc cugcccaucu acgccgccgu ggacaagaac      120

aacgccaccg ccgccgugca gaacgagagc aagagauaca ccgugagcua ccugaagacc      180

cugaacuacu acgaccuggu ggaccugcug gugaagaccg agaucgagaa ccugcccgac      240

cuguuccagu acagcagcga cgccaaggag uucuacggca acaagaccag aaugagcuuc      300

aucauggacg agaucggcag aagagccccc caguacaccg agaucgacca caagggcauc      360

cccacccugg uggagguggu gagagccggc uucuaccugg gcuuccacaa caaggagcug      420

aacgagauca acaagagaag cuucaaggag agagugaucc ccagcauccu ggccauccag      480

aagaacccca acuucaagcu gggcaccgag gugcaggaca agaucgugag cgccaccggc      540

cugcuggccg gcaacgagac cgcccccccc gaggugguga acaacuucac ccccauccug      600

caggacugca ucaagaacau cgacagauac gcccuggacg accugaagag caaggcccug      660

uucaacgugc uggccgcccc caccuacgac aucaccgagu accugagagc caccaaggag      720

aagcccgaga acacccccug guacggcaag aucgacggcu ucaucaacga gcugaagaag      780

cuggcccugu acggcaagau caacgacaac aacagcugga ucaucgacaa cggcaucuac      840

cacaucgccc cccugggcaa gcugcacagc aacaacaaga ucggcaucga gacccugacc      900

gaggugauga agguguaccc cuaccugagc augcagcacc ugcagagcgc cgaccagauc      960

aagagacacu acgacagcaa ggacgccgag ggcaacaaga ucccccugga caaguucaag     1020

aaggagggca aggagaagua cugccccaag accuacaccu ucgacgacgg caaggugauc     1080

aucaaggccg gcgccagagu ggaggaggag aaggugaaga gacuguacug ggccagcaag     1140

gaggugaaca gccaguucuu cagaguguac ggcaucgaca agccccugga ggagggcaac     1200

cccgacgaca uccugaccau ggugaucuac aacagccccg aggaguacaa gcugaacagc     1260

gugcuguacg gcuacgacac caacaacggc ggcauguaca ucgagcccga gggcaccuuc     1320

uucaccuacg agagagaggc ccaggagagc accuacaccc uggaggagcu guucagacac     1380

gaguacaccc acuaccugca gggcagauac gccgugcccg gccagugggg cagaaccaag     1440

cuguacgaca acgacagacu gaccugguac gaggagggcg gcgccgagcu guucgccggc     1500

agcaccagaa ccagcggcau ccugcccaga aagagcaucg ugagcaacau ccacaacacc     1560

accagaaaca acagauacaa gcugagcgac accgugcaca gcaaguacgg cgccagcuuc     1620

gaguucuaca acuacgccug cauguucaug gacuacaugu acaacaagga caugggcauc     1680

cugaacaagc ugaacgaccu ggccaagaac aacgacgugg acggcuacga caacuacauc     1740

agagaccuga gcagcaacua cgcccugaac gacaaguacc aggaccacau gcaggagaga     1800

aucgacaacu acgagaaccu gaccgugccc uucguggccg acgacuaccu ggugagacac     1860

gccuacaaga accccaacga gaucuacagc gagaucagcg agguggccaa gcugaaggac     1920

gccaagagcg aggugaagaa gagccaguac uucagcaccu ucacccugag aggcagcuac     1980

accggcggcg ccagcaaggg caagcuggag gaccagaagg ccaugaacaa guucaucgac     2040

gacagccuga agaagcugga caccuacagc uggagcggcu acaagacccu gaccgccuac     2100

uucaccaacu acaaggugga cagcagcaac agagugaccu acgacguggu guuccacggc     2160

uaccugccca acgagggcga cagcaagaac agccugcccu acggcaagau caacggcacc     2220

uacaagggca ccgagaagga gaagaucaag uucagcagcg agggcagcuu cgaccccgac     2280

ggcaagaucg ugagcuacga gugggacuuc ggcgacggca acaagagcaa cgaggagaac     2340

cccgagcaca gcuacgacaa ggugggcacc uacaccguga agcugaaggu gaccgacgac     2400

aagggcgaga gcagcgugag caccaccacc gccgagauca aggaccugag cgagaacaag     2460

cugcccguga ucuacaugca cgugcccaag agcggcgccc ugaaccagaa ggugguguuc     2520

uacggcaagg gcaccuacga ccccgacggc agcaucgccg gcuaccagug ggacuucggc     2580

gacggcagcg acuucagcag cgagcagaac cccagccacg uguacaccaa gaagggcgag     2640

uacaccguga cccugagagu gauggacagc agcggccaga ugagcgagaa gaccaugaag     2700

aucaagauca ccgaccccgu guaccccauc ggcaccgaga aggagcccaa caacagcaag     2760

gagaccgcca gcggccccau cgugcccggc auccccguga gcggcaccau cgagaacacc     2820

agcgaccagg acuacuucua cuucgacgug aucacccccg gcgaggugaa gaucgacauc     2880

aacaagcugg gcuacggcgg cgccaccugg gugguguacg acgagaacaa caacgccgug     2940

agcuacgcca ccgacgacgg ccagaaccug agcggcaagu ucaaggccga caagcccggc     3000

agauacuaca uccaccugua cauguucaac ggcagcuaca ugcccuacag aaucaacauc     3060

gagggcagcg ugggcagaug aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  1766
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt4)

<400>  1766
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcuguuccu guucagcagc       60

gccuacagcg ugcagaacga gagcaagaga uacaccguga gcuaccugaa gacccugaac      120

uacuacgacc ugguggaccu gcuggugaag accgagaucg agaaccugcc cgaccuguuc      180

caguacagca gcgacgccaa ggaguucuac ggcaacaaga ccagaaugag cuucaucaug      240

gacgagaucg gcagaagagc cccccaguac accgagaucg accacaaggg cauccccacc      300

cugguggagg uggugagagc cggcuucuac cugggcuucc acaacaagga gcugaacgag      360

aucaacaaga gaagcuucaa ggagagagug auccccagca uccuggccau ccagaagaac      420

cccaacuuca agcugggcac cgaggugcag gacaagaucg ugagcgccac cggccugcug      480

gccggcaacg agaccgcccc ccccgaggug gugaacaacu ucacccccau ccugcaggac      540

ugcaucaaga acaucgacag auacgcccug gacgaccuga agagcaaggc ccuguucaac      600

gugcuggccg cccccaccua cgacaucacc gaguaccuga gagccaccaa ggagaagccc      660

gagaacaccc ccugguacgg caagaucgac ggcuucauca acgagcugaa gaagcuggcc      720

cuguacggca agaucaacga caacaacagc uggaucaucg acaacggcau cuaccacauc      780

gccccccugg gcaagcugca cagcaacaac aagaucggca ucgagacccu gaccgaggug      840

augaaggugu accccuaccu gagcaugcag caccugcaga gcgccgacca gaucaagaga      900

cacuacgaca gcaaggacgc cgagggcaac aagauccccc uggacaaguu caagaaggag      960

ggcaaggaga aguacugccc caagaccuac accuucgacg acggcaaggu gaucaucaag     1020

gccggcgcca gaguggagga ggagaaggug aagagacugu acugggccag caaggaggug     1080

aacagccagu ucuucagagu guacggcauc gacaagcccc uggaggaggg caaccccgac     1140

gacauccuga ccauggugau cuacaacagc cccgaggagu acaagcugaa cagcgugcug     1200

uacggcuacg acaccaacaa cggcggcaug uacaucgagc ccgagggcac cuucuucacc     1260

uacgagagag aggcccagga gagcaccuac acccuggagg agcuguucag acacgaguac     1320

acccacuacc ugcagggcag auacgccgug cccggccagu ggggcagaac caagcuguac     1380

gacaacgaca gacugaccug guacgaggag ggcggcgccg agcuguucgc cggcagcacc     1440

agaaccagcg gcauccugcc cagaaagagc aucgugagca acauccacaa caccaccaga     1500

aacaacagau acaagcugag cgacaccgug cacagcaagu acggcgccag cuucgaguuc     1560

uacaacuacg ccugcauguu cauggacuac auguacaaca aggacauggg cauccugaac     1620

aagcugaacg accuggccaa gaacaacgac guggacggcu acgacaacua caucagagac     1680

cugagcagca acuacgcccu gaacgacaag uaccaggacc acaugcagga gagaaucgac     1740

aacuacgaga accugaccgu gcccuucgug gccgacgacu accuggugag acacgccuac     1800

aagaacccca acgagaucua cagcgagauc agcgaggugg ccaagcugaa ggacgccaag     1860

agcgagguga agaagagcca guacuucagc accuucaccc ugagaggcag cuacaccggc     1920

ggcgccagca agggcaagcu ggaggaccag aaggccauga acaaguucau cgacgacagc     1980

cugaagaagc uggacaccua cagcuggagc ggcuacaaga cccugaccgc cuacuucacc     2040

aacuacaagg uggacagcag caacagagug accuacgacg ugguguucca cggcuaccug     2100

cccaacgagg gcgacagcaa gaacagccug cccuacggca agaucaacgg caccuacaag     2160

ggcaccgaga aggagaagau caaguucagc agcgagggca gcuucgaccc cgacggcaag     2220

aucgugagcu acgaguggga cuucggcgac ggcaacaaga gcaacgagga gaaccccgag     2280

cacagcuacg acaagguggg caccuacacc gugaagcuga aggugaccga cgacaagggc     2340

gagagcagcg ugagcaccac caccgccgag aucaaggacc ugagcgagaa caagcugccc     2400

gugaucuaca ugcacgugcc caagagcggc gcccugaacc agaagguggu guucuacggc     2460

aagggcaccu acgaccccga cggcagcauc gccggcuacc agugggacuu cggcgacggc     2520

agcgacuuca gcagcgagca gaaccccagc cacguguaca ccaagaaggg cgaguacacc     2580

gugacccuga gagugaugga cagcagcggc cagaugagcg agaagaccau gaagaucaag     2640

aucaccgacc ccguguaccc caucggcacc gagaaggagc ccaacaacag caaggagacc     2700

gccagcggcc ccaucgugcc cggcaucccc gugagcggca ccaucgagaa caccagcgac     2760

caggacuacu ucuacuucga cgugaucacc cccggcgagg ugaagaucga caucaacaag     2820

cugggcuacg gcggcgccac cuggguggug uacgacgaga acaacaacgc cgugagcuac     2880

gccaccgacg acggccagaa ccugagcggc aaguucaagg ccgacaagcc cggcagauac     2940

uacauccacc uguacauguu caacggcagc uacaugcccu acagaaucaa caucgagggc     3000

agcgugggca gaugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1767
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt4)

<400>  1767
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcuguuccu guucagcagc       60

gccuacagca ugaagagaaa gugccugagc aagagacuga ugcuggccau caccauggcc      120

accaucuuca ccgugaacag cacccugccc aucuacgccg ccguggacaa gaacaacgcc      180

accgccgcca gaagaagaag aaagagagug cagaacgaga gcaagagaua caccgugagc      240

uaccugaaga cccugaacua cuacgaccug guggaccugc uggugaagac cgagaucgag      300

aaccugcccg accuguucca guacagcagc gacgccaagg aguucuacgg caacaagacc      360

agaaugagcu ucaucaugga cgagaucggc agaagagccc cccaguacac cgagaucgac      420

cacaagggca uccccacccu gguggaggug gugagagccg gcuucuaccu gggcuuccac      480

aacaaggagc ugaacgagau caacaagaga agcuucaagg agagagugau ccccagcauc      540

cuggccaucc agaagaaccc caacuucaag cugggcaccg aggugcagga caagaucgug      600

agcgccaccg gccugcuggc cggcaacgag accgcccccc ccgagguggu gaacaacuuc      660

acccccaucc ugcaggacug caucaagaac aucgacagau acgcccugga cgaccugaag      720

agcaaggccc uguucaacgu gcuggccgcc cccaccuacg acaucaccga guaccugaga      780

gccaccaagg agaagcccga gaacaccccc ugguacggca agaucgacgg cuucaucaac      840

gagcugaaga agcuggcccu guacggcaag aucaacgaca acaacagcug gaucaucgac      900

aacggcaucu accacaucgc cccccugggc aagcugcaca gcaacaacaa gaucggcauc      960

gagacccuga ccgaggugau gaagguguac cccuaccuga gcaugcagca ccugcagagc     1020

gccgaccaga ucaagagaca cuacgacagc aaggacgccg agggcaacaa gaucccccug     1080

gacaaguuca agaaggaggg caaggagaag uacugcccca agaccuacac cuucgacgac     1140

ggcaagguga ucaucaaggc cggcgccaga guggaggagg agaaggugaa gagacuguac     1200

ugggccagca aggaggugaa cagccaguuc uucagagugu acggcaucga caagccccug     1260

gaggagggca accccgacga cauccugacc auggugaucu acaacagccc cgaggaguac     1320

aagcugaaca gcgugcugua cggcuacgac accaacaacg gcggcaugua caucgagccc     1380

gagggcaccu ucuucaccua cgagagagag gcccaggaga gcaccuacac ccuggaggag     1440

cuguucagac acgaguacac ccacuaccug cagggcagau acgccgugcc cggccagugg     1500

ggcagaacca agcuguacga caacgacaga cugaccuggu acgaggaggg cggcgccgag     1560

cuguucgccg gcagcaccag aaccagcggc auccugccca gaaagagcau cgugagcaac     1620

auccacaaca ccaccagaaa caacagauac aagcugagcg acaccgugca cagcaaguac     1680

ggcgccagcu ucgaguucua caacuacgcc ugcauguuca uggacuacau guacaacaag     1740

gacaugggca uccugaacaa gcugaacgac cuggccaaga acaacgacgu ggacggcuac     1800

gacaacuaca ucagagaccu gagcagcaac uacgcccuga acgacaagua ccaggaccac     1860

augcaggaga gaaucgacaa cuacgagaac cugaccgugc ccuucguggc cgacgacuac     1920

cuggugagac acgccuacaa gaaccccaac gagaucuaca gcgagaucag cgagguggcc     1980

aagcugaagg acgccaagag cgaggugaag aagagccagu acuucagcac cuucacccug     2040

agaggcagcu acaccggcgg cgccagcaag ggcaagcugg aggaccagaa ggccaugaac     2100

aaguucaucg acgacagccu gaagaagcug gacaccuaca gcuggagcgg cuacaagacc     2160

cugaccgccu acuucaccaa cuacaaggug gacagcagca acagagugac cuacgacgug     2220

guguuccacg gcuaccugcc caacgagggc gacagcaaga acagccugcc cuacggcaag     2280

aucaacggca ccuacaaggg caccgagaag gagaagauca aguucagcag cgagggcagc     2340

uucgaccccg acggcaagau cgugagcuac gagugggacu ucggcgacgg caacaagagc     2400

aacgaggaga accccgagca cagcuacgac aaggugggca ccuacaccgu gaagcugaag     2460

gugaccgacg acaagggcga gagcagcgug agcaccacca ccgccgagau caaggaccug     2520

agcgagaaca agcugcccgu gaucuacaug cacgugccca agagcggcgc ccugaaccag     2580

aagguggugu ucuacggcaa gggcaccuac gaccccgacg gcagcaucgc cggcuaccag     2640

ugggacuucg gcgacggcag cgacuucagc agcgagcaga accccagcca cguguacacc     2700

aagaagggcg aguacaccgu gacccugaga gugauggaca gcagcggcca gaugagcgag     2760

aagaccauga agaucaagau caccgacccc guguacccca ucggcaccga gaaggagccc     2820

aacaacagca aggagaccgc cagcggcccc aucgugcccg gcauccccgu gagcggcacc     2880

aucgagaaca ccagcgacca ggacuacuuc uacuucgacg ugaucacccc cggcgaggug     2940

aagaucgaca ucaacaagcu gggcuacggc ggcgccaccu ggguggugua cgacgagaac     3000

aacaacgccg ugagcuacgc caccgacgac ggccagaacc ugagcggcaa guucaaggcc     3060

gacaagcccg gcagauacua cauccaccug uacauguuca acggcagcua caugcccuac     3120

agaaucaaca ucgagggcag cgugggcaga ugaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  1768
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt4)

<400>  1768
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccugcuggg cgccgccuuc       60

gccaugcccc ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug      120

cugacccccc ugaaguggua ccagagcauc agaccccccu accccagcua cggcuacgag      180

cccaugggcg gcuggcugca ccaccagauc auccccgugc ugagccagca gcaccccccc      240

acccacaccc ugcagcccca ccaccacauc cccguggugc ccgcccagca gcccgugauc      300

ccccagcagc ccaugaugcc cgugcccggc cagcacagca ugacccccau ccagcaccac      360

cagcccaacc ugcccccccc cgcccagcag cccuaccagc cccagcccgu gcagccccag      420

ccccaccagc ccaugcagcc ccagcccccc gugcacccca ugcagccccu gcccccccag      480

cccccccugc cccccauguu ccccaugcag ccccugcccc ccaugcugcc cgaccugacc      540

cuggaggccu ggcccagcac cgacaagacc aagagagagg agguggacug aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  1769
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt4)

<400>  1769
gggagaaagc uuaccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc       60

agcuacgagg ugcugacccc ccugaagugg uaccagagca ucagaccccc cuaccccagc      120

uacggcuacg agcccauggg cggcugguga ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  1770
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt4)

<400>  1770
gggagaaagc uuaccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc       60

agcuacgagg ugcugacccc ccugaagugg uaccagagca ucagaccccc ccccaugcug      120

cccgaccuga cccuggaggc cuggcccagc accgacaaga ccaagagaga ggagguggac      180

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  1771
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt4)

<400>  1771
gggagaaagc uuaccauggc cgugauggcc cccagaaccc uggugcugcu gcugagcggc       60

gcccuggccc ugacccagac cugggccaug ccccugcccc cccaccccgg ccaccccggc      120

uacaucaacu ucagcuacga ggugcugacc ccccugaagu gguaccagag caucagaccc      180

cccuacccca gcuacggcua cgagcccaug ggcggcuggu gaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  1772
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt4)

<400>  1772
gggagaaagc uuaccauggc cgugauggcc cccagaaccc uggugcugcu gcugagcggc       60

gcccuggccc ugacccagac cugggccaug ccccugcccc cccaccccgg ccaccccggc      120

uacaucaacu ucagcuacga ggugcugacc ccccugaagu gguaccagag caucagaccc      180

ccccccaugc ugcccgaccu gacccuggag gccuggccca gcaccgacaa gaccaagaga      240

gaggaggugg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  1773
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt4)

<400>  1773
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccugguggg cgccgccuuc       60

gccaugcccc ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug      120

cugacccccc ugaaguggua ccagagcaug aucagacccc ccuacagcag cuacggcuac      180

gagcccaugg gcggcuggcu gcaccaccag aucauccccg uggugagcca gcagcacccc      240

cugacccaca cccugcagag ccaccaccac auccccgugg ugcccgccca gcagcccaga      300

gugagacagc aggcccugau gcccgugccc ggccagcaga gcaugacccc cacccagcac      360

caccagccca accugccccu gcccgcccag cagcccuucc agccccagcc cgugcagccc      420

cagccccacc agcccaugca gccccagccc cccgugcagc ccaugcagcc ccugcugccc      480

cagccccccc ugccccccau guucccccug agaccccugc cccccauccu gcccgaccug      540

caccuggagg ccuggcccgc caccgacaag accaagcagg aggaggugga cugaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  1774
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt4)

<400>  1774
gggagaaagc uuaccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc       60

agcuacgagg ugcugacccc ccugaagugg uaccagagca ugaucagacc ccccuacagc      120

agcuacggcu acgagcccau gggcggcugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1775
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt4)

<400>  1775
gggagaaagc uuaccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc       60

agcuacgagg ugcugacccc ccugaagugg uaccagagca ugaucagacc cccccccauc      120

cugcccgacc ugcaccugga ggccuggccc gccaccgaca agaccaagca ggaggaggug      180

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1776
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt4)

<400>  1776
gggagaaagc uuaccauggc cgugauggcc cccagaaccc uggugcugcu gcugagcggc       60

gcccuggccc ugacccagac cugggccaug ccccugcccc cccaccccgg ccaccccggc      120

uacaucaacu ucagcuacga ggugcugacc ccccugaagu gguaccagag caugaucaga      180

ccccccuaca gcagcuacgg cuacgagccc augggcggcu ggugaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1777
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt4)

<400>  1777
gggagaaagc uuaccauggc cgugauggcc cccagaaccc uggugcugcu gcugagcggc       60

gcccuggccc ugacccagac cugggccaug ccccugcccc cccaccccgg ccaccccggc      120

uacaucaacu ucagcuacga ggugcugacc ccccugaagu gguaccagag caugaucaga      180

ccccccccca uccugcccga ccugcaccug gaggccuggc ccgccaccga caagaccaag      240

caggaggagg uggacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1778
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt4)

<400>  1778
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccugcuggg cgccgccuuc       60

agcaugcccc ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug      120

cugacccccc ugaaguggua ccagaacaug aucagacacc ccuacaccag cuacggcuac      180

gagcccaugg gcggcuggcu gcaccaccag aucauccccg uggugagcca gcagaccccc      240

cagagccacg cccugcagcc ccaccaccac auccccaugg ugcccgccca gcagcccggc      300

aucccccagc agcccaugau gccccugccc ggccagcaca gcaugacccc cacccagcac      360

caccagccca accugccccu gcccgcccag cagcccuucc agccccagcc cgugcagccc      420

cagccccacc agccccugca gccccagagc cccaugcacc ccauccagcc ccugcugccc      480

cagccccccc ugccccccau guucagcaug cagagccugc ugcccgaccu gccccuggag      540

gccuggcccg ccaccgacaa gaccaagaga gaggaggugg acugaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1779
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt4)

<400>  1779
gggagaaagc uuaccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc       60

agcuacgagg ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccuacacc      120

agcuacggcu acgagcccau gggcggcugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1780
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt4)

<400>  1780
gggagaaagc uuaccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc       60

agcuacgagg ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccagccug      120

cugcccgacc ugccccugga ggccuggccc gccaccgaca agaccaagag agaggaggug      180

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1781
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt4)

<400>  1781
gggagaaagc uuaccauggc cgugauggcc cccagaaccc uggugcugcu gcugagcggc       60

gcccuggccc ugacccagac cugggccaug ccccugcccc cccaccccgg ccaccccggc      120

uacaucaacu ucagcuacga ggugcugacc ccccugaagu gguaccagaa caugaucaga      180

caccccuaca ccagcuacgg cuacgagccc augggcggcu ggugaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1782
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt4)

<400>  1782
gggagaaagc uuaccauggc cgugauggcc cccagaaccc uggugcugcu gcugagcggc       60

gcccuggccc ugacccagac cugggccaug ccccugcccc cccaccccgg ccaccccggc      120

uacaucaacu ucagcuacga ggugcugacc ccccugaagu gguaccagaa caugaucaga      180

caccccagcc ugcugcccga ccugccccug gaggccuggc ccgccaccga caagaccaag      240

agagaggagg uggacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1783
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt4)

<400>  1783
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccugcuggg cgccgccuuc       60

agcaugcccc ugccccccca ccccggccac cccggcuaca ucaacuucag cuacaucaga      120

caccccuaca ccagcuacgg cuacgagccc augggcggcu ggcugcacca ccagaucauc      180

cccgugguga gccagcagac cccccagagc cacgcccugc agccccacca ccacaucccc      240

auggugcccg cccagcagcc cggcaucccc cagcagccca ugaugccccu gcccggccag      300

cacagcauga cccccaccca gcaccaccag cccaaccugc cccugcccgc ccagcagccc      360

uuccagcccc agcccgugca gccccagccc caccagcccc ugcagcccca gagccccaug      420

caccccaucc agccccugcu gccccagccc ccccugcccc ccauguucag caugcagagc      480

cugcugcccg accugccccu ggaggccugg cccgccaccg acaagaccaa gagagaggag      540

guggacugag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  1784
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt4)

<400>  1784
gggagaaagc uuaccauggg caccuggauc uucuucgccu gccugcuggg cgccagccug       60

gccaugcccc ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug      120

cugacccccc ugaaguggua ccagaacaug aucagacacc ccuacaccag cuacggcuac      180

gagcccaugg gcggcuggcu gcaccaccag aucauccccg uggugagcca gcagaccccc      240

cagagccacg cccugcagcc ccaccaccac auccccaugg ugcccgccca gcagcccggc      300

aucccccagc agcccaugau gccccugccc ggccagcaca gcaugacccc cacccagcac      360

caccagccca accugccccu gcccgcccag cagcccuucc agccccagcc cgugcagccc      420

cagccccacc agccccugca gccccagagc cccaugcacc ccauccagcc ccugcugccc      480

cagccccccc ugccccccau guucagcaug cagagccugc ugcccgaccu gccccuggag      540

gccuggcccg ccaccgacaa gaccaagaga gaggaggugg acugaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1785
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt4)

<400>  1785
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccugcuggg cgccgccuuc       60

agcaugcccc ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug      120

cugacccccc ugaaguggua ccagaacaug aucagacacc ccagccugcu gcccgaccug      180

ccccuggagg ccuggcccgc caccgacaag accaagagag aggaggugga cugaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  1786
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt4)

<400>  1786
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccugcuggg cgccgccuuc       60

agcaugcccc ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggac      120

cuguaccugg aggccaucag aaucgacaga accgccuucg ugcugacccc ccugaagugg      180

uaccagaaca ugaucagaca ccccuacacc agcuacggcu acgagcccau gggcggcugg      240

cugcaccacc agaucauccc cguggugagc cagcagaccc cccagagcca cgcccugcag      300

ccccaccacc acauccccau ggugcccgcc cagcagcccg gcauccccca gcagcccaug      360

augccccugc ccggccagca cagcaugacc cccacccagc accaccagcc caaccugccc      420

cugcccgccc agcagcccuu ccagccccag cccgugcagc cccagcccca ccagccccug      480

cagccccaga gccccaugca ccccauccag ccccugcugc cccagccccc ccugcccccc      540

auguucagca ugcagagccu gcugcccgac cugccccugg aggccuggcc cgccaccgac      600

aagaccaaga gagaggaggu ggacugagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  1787
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt4)

<400>  1787
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccugcuggg cgccgccuuc       60

agcaugcccc ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug      120

cugacccccc ugaaguggua ccagaacaug aucagacacc ccacccccca gagccacgcc      180

cugcagcccc accaccacau ccccauggug cccgcccagc agcccggcau cccccagcag      240

cccaugaugc cccugcccgg ccagcacagc augaccccca cccagcacca ccagcccaac      300

cugccccugc ccgcccagca gcccuuccag ccccagcccg ugcagcccca gccccaccag      360

ccccugcagc cccagagccc caugcacccc auccagcccc ugcugcccca gcccccccug      420

ccccccaugu ucagcaugca gagccugcug cccgaccugc cccuggaggc cuggcccgcc      480

accgacaaga ccaagagaga ggagguggac ugaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  1788
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt4)

<400>  1788
gggagaaagc uuaccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc       60

agcuacgagg ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccuacacc      120

agcuacggcu acgagcccau gggcggcugg cugcaccacc agaucauccc cguggugagc      180

cagcagaccc cccagagcca cgcccugcag ccccaccacc acauccccau ggugcccgcc      240

cagcagcccg gcauccccca gcagcccaug augccccugc ccggccagca cagcaugacc      300

cccacccagc accaccagcc caaccugccc cugcccgccc agcagcccuu ccagccccag      360

cccgugcagc cccagcccca ccagccccug cagccccaga gccccaugca ccccauccag      420

ccccugcugc cccagccccc ccugcccccc auguucagca ugcagagccu gcugcccgac      480

cugccccugg aggccuggcc cgccaccgac aagaccaaga gagaggaggu ggacugagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  1789
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt4)

<400>  1789
gggagaaagc uuaccaugcc cggcguggcc agacugcccc ugcugcuggg ccugcugcug       60

cugcccagac ccggcagacc ccuggaccug gccgacuaca ccuacgaccu ggccgaggag      120

gacgacagcg agccccugaa cuacaaggac cccugcaagg ccgccgccuu ccugggcgac      180

aucgcccugg acgaggagga ccugagagcc uuccaggugc agcaggccgu ggaccugaga      240

agacacaccg ccagaaagag cagcaucaag gccgccgugc ccggcaacac cagcaccccc      300

agcugccaga gcaccaacgg ccagccccag agaggcgccu gcggcagaug gagaggcaga      360

agcagaagca gaagagccgc caccagcaga cccgagagag uguggcccga cggcgugauc      420

cccuucguga ucggcggcaa cuucaccggc agccagagag ccguguucag acaggccaug      480

agacacuggg agaagcacac cugcgugacc uuccuggaga gaaccgacga ggacagcuac      540

aucguguuca ccuacagacc cugcggcugc ugcagcuacg ugggcagaag aggcggcggc      600

ccccaggcca ucagcaucgg caagaacugc gacaaguucg gcaucguggu gcacgagcug      660

ggccacgugg ugggcuucug gcacgagcac accagacccg acagagacag acacgugagc      720

aucgugagag agaacaucca gcccggccag gaguacaacu uccugaagau ggagccccag      780

gagguggaga gccugggcga gaccuacgac uucgacagca ucaugcacua cgccagaaac      840

accuucagca gaggcaucuu ccuggacacc aucgugccca aguacgaggu gaacggcgug      900

aagcccccca ucggccagag aaccagacug agcaagggcg acaucgccca ggccagaaag      960

cuguacaagu gccccgccug cggcgagacc cugcaggaca gcaccggcaa cuucagcagc     1020

cccgaguacc ccaacggcua cagcgcccac augcacugcg uguggagaau cagcgugacc     1080

cccggcgaga agaucauccu gaacuucacc agccuggacc uguacagaag cagacugugc     1140

ugguacgacu acguggaggu gagagacggc uucuggagaa aggccccccu gagaggcaga     1200

uucugcggca gcaagcugcc cgagcccauc gugagcaccg acagcagacu guggguggag     1260

uucagaagca gcagcaacug ggugggcaag ggcuucuucg ccguguacga ggccaucugc     1320

ggcggcgacg ugaagaagga cuacggccac auccagagcc ccaacuaccc cgacgacuac     1380

agacccagca aggugugcau cuggagaauc caggugagcg agggcuucca cgugggccug     1440

accuuccaga gcuucgagau cgagagacac gacagcugcg ccuacgacua ccuggaggug     1500

agagacggcc acagcgagag cagcacccug aucggcagau acugcggcua cgagaagccc     1560

gacgacauca agagcaccag cagcagacug uggcugaagu ucgugagcga cggcagcauc     1620

aacaaggccg gcuucgccgu gaacuucuuc aaggaggugg acgagugcag cagacccaac     1680

agaggcggcu gcgagcagag augccugaac acccugggca gcuacaagug cagcugcgac     1740

cccggcuacg agcuggcccc cgacaagaga agaugcgagg ccgccugcgg cggcuuccug     1800

accaagcuga acggcagcau caccagcccc ggcuggccca aggaguaccc ccccaacaag     1860

aacugcaucu ggcagcuggu ggcccccacc caguacagaa ucagccugca guucgacuuc     1920

uucgagaccg agggcaacga cgugugcaag uacgacuucg uggaggugag aagcggccug     1980

accgccgaca gcaagcugca cggcaaguuc ugcggcagcg agaagcccga ggugaucacc     2040

agccaguaca acaacaugag aguggaguuc aagagcgaca acaccgugag caagaagggc     2100

uucaaggccc acuucuucag cgacaaggac gagugcagca aggacaacgg cggcugccag     2160

caggacugcg ugaacaccuu cggcagcuac gagugccagu gcagaagcgg cuucgugcug     2220

cacgacaaca agcacgacug caaggaggcc ggcugcgacc acaaggugac cagcaccagc     2280

ggcaccauca ccagccccaa cuggcccgac aaguacccca gcaagaagga gugcaccugg     2340

gccaucagca gcacccccgg ccacagagug aagcugaccu ucauggagau ggacaucgag     2400

agccagcccg agugcgccua cgaccaccug gagguguucg acggcagaga cgccaaggcc     2460

cccgugcugg gcagauucug cggcagcaag aagcccgagc ccgugcuggc caccggcagc     2520

agaauguucc ugagauucua cagcgacaac agcgugcaga gaaagggcuu ccaggccagc     2580

cacgccaccg agugcggcgg ccaggugaga gccgacguga agaccaagga ccuguacagc     2640

cacgcccagu ucggcgacaa caacuacccc ggcggcgugg acugcgagug ggugaucgug     2700

gccgaggagg gcuacggcgu ggagcuggug uuccagaccu ucgaggugga ggaggagacc     2760

gacugcggcu acgacuacau ggagcuguuc gacggcuacg acagcaccgc ccccagacug     2820

ggcagauacu gcggcagcgg cccccccgag gagguguaca gcgccggcga cagcgugcug     2880

gugaaguucc acagcgacga caccaucacc aagaagggcu uccaccugag auacaccagc     2940

accaaguucc aggacacccu gcacagcaga aagugaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  1790
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt4)

<400>  1790
gggagaaagc uuaccauggu ggccggcacc agaugccugc uggcccugcu gcugccccag       60

gugcugcugg gcggcgccgc cggccuggug cccgagcugg gcagaagaaa guucgccgcc      120

gccagcagcg gcagacccag cagccagccc agcgacgagg ugcugagcga guucgagcug      180

agacugcuga gcauguucgg ccugaagcag agacccaccc ccagcagaga cgccguggug      240

ccccccuaca ugcuggaccu guacagaaga cacagcggcc agcccggcag ccccgccccc      300

gaccacagac uggagagagc cgccagcaga gccaacaccg ugagaagcuu ccaccacgag      360

gagagccugg aggagcugcc cgagaccagc ggcaagacca ccagaagauu cuucuucaac      420

cugagcagca uccccaccga ggaguucauc accagcgccg agcugcaggu guucagagag      480

cagaugcagg acgcccuggg caacaacagc agcuuccacc acagaaucaa caucuacgag      540

aucaucaagc ccgccaccgc caacagcaag uuccccguga ccagacugcu ggacaccaga      600

cuggugaacc agaacgccag cagaugggag agcuucgacg ugacccccgc cgugaugaga      660

uggaccgccc agggccacgc caaccacggc uucguggugg agguggccca ccuggaggag      720

aagcagggcg ugagcaagag acacgugaga aucagcagaa gccugcacca ggacgagcac      780

agcuggagcc agaucagacc ccugcuggug accuucggcc acgacggcaa gggccacccc      840

cugcacaaga gagagaagag acaggccaag cacaagcaga gaaagagacu gaagagcagc      900

ugcaagagac acccccugua cguggacuuc agcgacgugg gcuggaacga cuggaucgug      960

gccccccccg gcuaccacgc cuucuacugc cacggcgagu gccccuuccc ccuggccgac     1020

caccugaaca gcaccaacca cgccaucgug cagacccugg ugaacagcgu gaacagcaag     1080

auccccaagg ccugcugcgu gcccaccgag cugagcgcca ucagcaugcu guaccuggac     1140

gagaacgaga agguggugcu gaagaacuac caggacaugg ugguggaggg cugcggcugc     1200

agaugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  1791
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt4)

<400>  1791
gggagaaagc uuaccaugau ccccggcaac agaaugcuga ugguggugcu gcugugccag       60

gugcugcugg gcggcgccag ccacgccagc cugauccccg agaccggcaa gaagaaggug      120

gccgagaucc agggccacgc cggcggcaga agaagcggcc agagccacga gcugcugaga      180

gacuucgagg ccacccugcu gcagauguuc ggccugagaa gaagacccca gcccagcaag      240

agcgccguga uccccgacua caugagagac cuguacagac ugcagagcgg cgaggaggag      300

gaggagcaga uccacagcac cggccuggag uaccccgaga gacccgccag cagagccaac      360

accgugagaa gcuuccacca cgaggagcac cuggagaaca uccccggcac cagcgagaac      420

agcgccuuca gauuccuguu caaccugagc agcauccccg agaacgaggu gaucagcagc      480

gccgagcuga gacuguucag agagcaggug gaccagggcc ccgacuggga gagaggcuuc      540

cacagaauca acaucuacga ggugaugaag ccccccgccg agguggugcc cggccaccug      600

aucaccagac ugcuggacac cagacuggug caccacaacg ugaccagaug ggagaccuuc      660

gacgugagcc ccgccgugcu gagauggacc agagagaagc agcccaacua cggccuggcc      720

aucgagguga cccaccugca ccagaccaga acccaccagg gccagcacgu gagaaucagc      780

agaagccugc cccagggcag cggcaacugg gcccagcuga gaccccugcu ggugaccuuc      840

ggccacgacg gcagaggcca cgcccugacc agaagaagaa gagccaagag aagccccaag      900

caccacagcc agagagccag aaagaagaac aagaacugca gaagacacag ccuguacgug      960

gacuucagcg acgugggcug gaacgacugg aucguggccc cccccggcua ccaggccuuc     1020

uacugccacg gcgacugccc cuucccccug gccgaccacc ugaacagcac caaccacgcc     1080

aucgugcaga cccuggugaa cagcgugaac agcagcaucc ccaaggccug cugcgugccc     1140

accgagcuga gcgccaucag caugcuguac cuggacgagu acgacaaggu ggugcugaag     1200

aacuaccagg agaugguggu ggagggcugc ggcugcagau gaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  1792
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt4)

<400>  1792
gggagaaagc uuaccaugcc cggccugggc agaagagccc aguggcugug cugguggugg       60

ggccugcugu gcagcugcug cggccccccc ccccugagac ccccccugcc cgccgccgcc      120

gccgccgccg ccggcggcca gcugcugggc gacggcggca gccccggcag aaccgagcag      180

ccccccccca gcccccagag cagcagcggc uuccuguaca gaagacugaa gacccaggag      240

aagagagaga ugcagaagga gauccugagc gugcugggcc ugccccacag acccagaccc      300

cugcacggcc ugcagcagcc ccagcccccc gcccugagac agcaggagga gcagcagcag      360

cagcagcagc ugcccagagg cgagcccccc cccggcagac ugaagagcgc cccccuguuc      420

augcuggacc uguacaacgc ccugagcgcc gacaacgacg aggacggcgc cagcgagggc      480

gagagacagc agagcuggcc ccacgaggcc gccagcagca gccagagaag acagcccccc      540

cccggcgccg cccacccccu gaacagaaag agccugcugg cccccggcag cggcagcggc      600

ggcgccagcc cccugaccag cgcccaggac agcgccuucc ugaacgacgc cgacauggug      660

augagcuucg ugaaccuggu ggaguacgac aaggaguuca gccccagaca gagacaccac      720

aaggaguuca aguucaaccu gagccagauc cccgagggcg agguggugac cgccgccgag      780

uucagaaucu acaaggacug cgugaugggc agcuucaaga accagaccuu ccugaucagc      840

aucuaccagg ugcugcagga gcaccagcac agagacagcg accuguuccu gcuggacacc      900

agaguggugu gggccagcga ggagggcugg cuggaguucg acaucaccgc caccagcaac      960

cugugggugg ugacccccca gcacaacaug ggccugcagc ugagcguggu gaccagagac     1020

ggcgugcacg ugcaccccag agccgccggc cuggugggca gagacggccc cuacgacaag     1080

cagcccuuca ugguggccuu cuucaaggug agcgaggugc acgugagaac caccagaagc     1140

gccagcagca gaagaagaca gcagagcaga aacagaagca cccagagcca ggacguggcc     1200

agagugagca gcgccagcga cuacaacagc agcgagcuga agaccgccug cagaaagcac     1260

gagcuguacg ugagcuucca ggaccugggc uggcaggacu ggaucaucgc ccccaagggc     1320

uacgccgcca acuacugcga cggcgagugc agcuuccccc ugaacgccca caugaacgcc     1380

accaaccacg ccaucgugca gacccuggug caccugauga accccgagua cgugcccaag     1440

cccugcugcg cccccaccaa gcugaacgcc aucagcgugc uguacuucga cgacaacagc     1500

aacgugaucc ugaagaagua cagaaacaug guggugagag ccugcggcug ccacugagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  1793
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt4)

<400>  1793
gggagaaagc uuaccaugca cgugagaagc cugagagccg ccgcccccca cagcuucgug       60

gcccuguggg ccccccuguu ccugcugaga agcgcccugg ccgacuucag ccuggacaac      120

gaggugcaca gcagcuucau ccacagaaga cugagaagcc aggagagaag agagaugcag      180

agagagaucc ugagcauccu gggccugccc cacagaccca gaccccaccu gcagggcaag      240

cacaacagcg cccccauguu caugcuggac cuguacaacg ccauggccgu ggaggagggc      300

ggcggccccg gcggccaggg cuucagcuac cccuacaagg ccguguucag cacccagggc      360

cccccccugg ccagccugca ggacagccac uuccugaccg acgccgacau ggugaugagc      420

uucgugaacc ugguggagca cgacaaggag uucuuccacc ccagauacca ccacagagag      480

uucagauucg accugagcaa gauccccgag ggcgaggccg ugaccgccgc cgaguucaga      540

aucuacaagg acuacaucag agagagauuc gacaacgaga ccuucagaau cagcguguac      600

caggugcugc aggagcaccu gggcagagag agcgaccugu uccugcugga cagcagaacc      660

cugugggcca gcgaggaggg cuggcuggug uucgacauca ccgccaccag caaccacugg      720

guggugaacc ccagacacaa ccugggccug cagcugagcg uggagacccu ggacggccag      780

agcaucaacc ccaagcuggc cggccugauc ggcagacacg gcccccagaa caagcagccc      840

uucauggugg ccuucuucaa ggccaccgag gugcacuuca gaagcaucag aagcaccggc      900

agcaagcaga gaagccagaa cagaagcaag acccccaaga accaggaggc ccugagaaug      960

gccaacgugg ccgagaacag cagcagcgac cagagacagg ccugcaagaa gcacgagcug     1020

uacgugagcu ucagagaccu gggcuggcag gacuggauca ucgcccccga gggcuacgcc     1080

gccuacuacu gcgagggcga gugcgccuuc ccccugaaca gcuacaugaa cgccaccaac     1140

cacgccaucg ugcagacccu ggugcacuuc aucaaccccg agaccgugcc caagcccugc     1200

ugcgccccca cccagcugaa cgccaucagc gugcuguacu ucgacgacag cagcaacgug     1260

auccugaaga aguacagaaa caugguggug agagccugcg gcugccacug aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  1794
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt4)

<400>  1794
gggagaaagc uuaccaugaa ggccagcgcc gcccugcugu gccugcugcu gaccgccgcc       60

gccuucagcc cccagggccu ggcccagccc gugggcauca acaccagcac caccugcugc      120

uacagauuca ucaacaagaa gauccccaag cagagacugg agagcuacag aagaaccacc      180

agcagccacu gccccagaga ggccgugauc uucaagacca agcuggacaa ggagaucugc      240

gccgacccca cccagaagug ggugcaggac uucaugaagc accuggacaa gaagacccag      300

acccccaagc ugugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  1795
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt4)

<400>  1795
gggagaaagc uuaccaugcu gcugacccug aucauccugc ugcccguggu gagcaaguuc       60

agcuucguga gccugagcgc cccccagcac uggagcugcc ccgagggcac ccuggccggc      120

aacggcaaca gcaccugcgu gggccccgcc cccuuccuga ucuucagcca cggcaacagc      180

aucuucagaa ucgacaccga gggcaccaac uacgagcagc ugguggugga cgccggcgug      240

agcgugauca uggacuucca cuacaacgag aagagaaucu acugggugga ccuggagaga      300

cagcugcugc agagaguguu ccugaacggc agcagacagg agagagugug caacaucgag      360

aagaacguga gcggcauggc caucaacugg aucaacgagg aggugaucug gagcaaccag      420

caggagggca ucaucaccgu gaccgacaug aagggcaaca acagccacau ccugcugagc      480

gcccugaagu accccgccaa cguggccgug gaccccgugg agagauucau cuucuggagc      540

agcgaggugg ccggcagccu guacagagcc gaccuggacg gcgugggcgu gaaggcccug      600

cuggagacca gcgagaagau caccgccgug agccuggacg ugcuggacaa gagacuguuc      660

uggauccagu acaacagaga gggcagcaac agccugaucu gcagcugcga cuacgacggc      720

ggcagcgugc acaucagcaa gcaccccacc cagcacaacc uguucgccau gagccuguuc      780

ggcgacagaa ucuucuacag caccuggaag augaagacca ucuggaucgc caacaagcac      840

accggcaagg acauggugag aaucaaccug cacagcagcu ucgugccccu gggcgagcug      900

aagguggugc acccccuggc ccagcccaag gccgaggacg acaccuggga gcccgagcag      960

aagcugugca agcugagaaa gggcaacugc agcagcaccg ugugcggcca ggaccugcag     1020

agccaccugu gcaugugcgc cgagggcuac gcccugagca gagacagaaa guacugcgag     1080

gacgugaacg agugcgccuu cuggaaccac ggcugcaccc ugggcugcaa gaacaccccc     1140

ggcagcuacu acugcaccug ccccgugggc uucgugcugc ugcccgacgg caagagaugc     1200

caccagcugg ugagcugccc cagaaacgug agcgagugca gccacgacug cgugcugacc     1260

agcgagggcc cccugugcuu cugccccgag ggcagcgugc uggagagaga cggcaagacc     1320

ugcagcggcu gcagcagccc cgacaacggc ggcugcagcc agcugugcgu gccccugagc     1380

cccgugagcu gggagugcga cugcuucccc ggcuacgacc ugcagcugga cgagaagagc     1440

ugcgccgcca gcggccccca gcccuuccug cuguucgcca acagccagga caucagacac     1500

augcacuucg acggcaccga cuacggcacc cugcugagcc agcagauggg caugguguac     1560

gcccuggacc acgaccccgu ggagaacaag aucuacuucg cccacaccgc ccugaagugg     1620

aucgagagag ccaacaugga cggcagccag agagagagac ugaucgagga gggcguggac     1680

gugcccgagg gccuggccgu ggacuggauc ggcagaagau ucuacuggac cgacagaggc     1740

aagagccuga ucggcagaag cgaccugaac ggcaagagaa gcaagaucau caccaaggag     1800

aacaucagcc agcccagagg caucgccgug caccccaugg ccaagagacu guucuggacc     1860

gacaccggca ucaaccccag aaucgagagc agcagccugc agggccuggg cagacuggug     1920

aucgccagca gcgaccugau cuggcccagc ggcaucacca ucgacuuccu gaccgacaag     1980

cuguacuggu gcgacgccaa gcagagcgug aucgagaugg ccaaccugga cggcagcaag     2040

agaagaagac ugacccagaa cgacgugggc caccccuucg ccguggccgu guucgaggac     2100

uacguguggu ucagcgacug ggccaugccc agcgugauga gagugaacaa gagaaccggc     2160

aaggacagag ugagacugca gggcagcaug cugaagccca gcagccuggu gguggugcac     2220

ccccuggcca agcccggcgc cgaccccugc cuguaccaga acggcggcug cgagcacauc     2280

ugcaagaaga gacugggcac cgccuggugc agcugcagag agggcuucau gaaggccagc     2340

gacggcaaga ccugccuggc ccuggacggc caccagcugc uggccggcgg cgagguggac     2400

cugaagaacc aggugacccc ccuggacauc cugagcaaga ccagagugag cgaggacaac     2460

aucaccgaga gccagcacau gcugguggcc gagaucaugg ugagcgacca ggacgacugc     2520

gcccccgugg gcugcagcau guacgccaga ugcaucagcg agggcgagga cgccaccugc     2580

cagugccuga agggcuucgc cggcgacggc aagcugugca gcgacaucga cgagugcgag     2640

augggcgugc ccgugugccc ccccgccagc agcaagugca ucaacaccga gggcggcuac     2700

gugugcagau gcagcgaggg cuaccagggc gacggcaucc acugccugga caucgacgag     2760

ugccagcugg gcgagcacag cugcggcgag aacgccagcu gcaccaacac cgagggcggc     2820

uacaccugca ugugcgccgg cagacugagc gagcccggcc ugaucugccc cgacagcacc     2880

cccccccccc accugagaga ggacgaccac cacuacagcg ugagaaacag cgacagcgag     2940

ugcccccuga gccacgacgg cuacugccug cacgacggcg ugugcaugua caucgaggcc     3000

cuggacaagu acgccugcaa cugcguggug ggcuacaucg gcgagagaug ccaguacaga     3060

gaccugaagu ggugggagcu gagacacgcc ggccacggcc agcagcagaa ggugaucgug     3120

guggccgugu gcgugguggu gcuggugaug cugcugcugc ugagccugug gggcgcccac     3180

uacuacagaa cccagaagcu gcugagcaag aaccccaaga accccuacga ggagagcagc     3240

agagacguga gaagcagaag acccgccgac accgaggacg gcaugagcag cugcccccag     3300

cccugguucg uggugaucaa ggagcaccag gaccugaaga acggcggcca gcccguggcc     3360

ggcgaggacg gccaggccgc cgacggcagc augcagccca ccagcuggag acaggagccc     3420

cagcugugcg gcaugggcac cgagcagggc ugcuggaucc ccgugagcag cgacaagggc     3480

agcugccccc aggugaugga gagaagcuuc cacaugccca gcuacggcac ccagacccug     3540

gagggcggcg uggagaagcc ccacagccug cugagcgcca acccccugug gcagcagaga     3600

gcccuggacc ccccccacca gauggagcug acccagugag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  1796
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt4)

<400>  1796
gggagaaagc uuaccaugac cgccggcaga agaauggaga ugcugugcgc cggcagagug       60

cccgcccugc ugcugugccu gggcuuccac cugcugcagg ccgugcugag caccaccgug      120

auccccagcu gcauccccgg cgagagcagc gacaacugca ccgcccuggu gcagaccgag      180

gacaacccca gaguggccca ggugagcauc accaagugca gcagcgacau gaacggcuac      240

ugccugcacg gccagugcau cuaccuggug gacaugagcc agaacuacug cagaugcgag      300

gugggcuaca ccggcgugag augcgagcac uucuuccuga ccgugcacca gccccugagc      360

aaggaguacg uggcccugac cgugauccug aucauccugu uccugaucac cguggugggc      420

agcaccuacu acuucugcag augguacaga aacagaaaga gcaaggagcc caagaaggag      480

uacgagagag ugaccagcgg cgaccccgag cugccccagg ugugaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  1797
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt4)

<400>  1797
gggagaaagc uuaccauggc cgagggcgag aucaccaccu ucaccgcccu gaccgagaag       60

uucaaccugc cccccggcaa cuacaagaag cccaagcugc uguacugcag caacggcggc      120

cacuuccuga gaauccugcc cgacggcacc guggacggca ccagagacag aagcgaccag      180

cacauccagc ugcagcugag cgccgagagc gugggcgagg uguacaucaa gagcaccgag      240

accggccagu accuggccau ggacaccgac ggccugcugu acggcagcca gacccccaac      300

gaggagugcc uguuccugga gagacuggag gagaaccacu acaacaccua caucagcaag      360

aagcacgccg agaagaacug guucgugggc cugaagaaga acggcagcug caagagaggc      420

cccagaaccc acuacggcca gaaggccauc cuguuccugc cccugcccgu gagcagcgac      480

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  1798
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt4)

<400>  1798
gggagaaagc uuaccauggu gggcgugggc ggcggcgacg uggaggacgu gacccccaga       60

cccggcggcu gccagaucag cggcagaggc gccagaggcu gcaacggcau ccccggcgcc      120

gccgccuggg aggccgcccu gcccagaaga agacccagaa gacaccccag cgugaacccc      180

agaagcagag ccgccggcag ccccagaacc agaggcagaa gaaccgagga gagacccagc      240

ggcagcagac ugggcgacag aggcagaggc agagcccugc ccggcggcag acugggcggc      300

agaggcagag gcagagcccc cgagagagug ggcggcagag gcagaggcag aggcaccgcc      360

gcccccagag ccgcccccgc cgccagaggc agcagacccg gccccgccgg caccauggcc      420

gccggcagca ucaccacccu gcccgcccug cccgaggacg gcggcagcgg cgccuucccc      480

cccggccacu ucaaggaccc caagagacug uacugcaaga acggcggcuu cuuccugaga      540

auccaccccg acggcagagu ggacggcgug agagagaaga gcgaccccca caucaagcug      600

cagcugcagg ccgaggagag aggcguggug agcaucaagg gcgugugcgc caacagauac      660

cuggccauga aggaggacgg cagacugcug gccagcaagu gcgugaccga cgagugcuuc      720

uucuucgaga gacuggagag caacaacuac aacaccuaca gaagcagaaa guacaccagc      780

ugguacgugg cccugaagag aaccggccag uacaagcugg gcagcaagac cggccccggc      840

cagaaggcca uccuguuccu gcccaugagc gccaagagcu gaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  1799
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt4)

<400>  1799
gggagaaagc uuaccaugca caaguggauc cugaccugga uccugcccac ccugcuguac       60

agaagcugcu uccacaucau cugccuggug ggcaccauca gccuggccug caacgacaug      120

acccccgagc agauggccac caacgugaac ugcagcagcc ccgagagaca caccagaagc      180

uacgacuaca uggagggcgg cgacaucaga gugagaagac uguucugcag aacccagugg      240

uaccugagaa ucgacaagag aggcaaggug aagggcaccc aggagaugaa gaacaacuac      300

aacaucaugg agaucagaac cguggccgug ggcaucgugg ccaucaaggg cguggagagc      360

gaguucuacc uggccaugaa caaggagggc aagcuguacg ccaagaagga gugcaacgag      420

gacugcaacu ucaaggagcu gauccuggag aaccacuaca acaccuacgc cagcgccaag      480

uggacccaca acggcggcga gauguucgug gcccugaacc agaagggcau ccccgugaga      540

ggcaagaaga ccaagaagga gcagaagacc gcccacuucc ugcccauggc caucaccuga      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  1800
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt4)

<400>  1800
gggagaaagc uuaccaugaa gcugcugccc agcguggugc ugaagcuguu ccuggccgcc       60

gugcugagcg cccuggugac cggcgagagc cuggagagac ugagaagagg ccuggccgcc      120

ggcaccagca accccgaccc ccccaccgug agcaccgacc agcugcugcc ccugggcggc      180

ggcagagaca gaaaggugag agaccugcag gaggccgacc uggaccugcu gagagugacc      240

cugagcagca agccccaggc ccuggccacc cccaacaagg aggagcacgg caagagaaag      300

aagaagggca agggccuggg caagaagaga gaccccugcc ugagaaagua caaggacuuc      360

ugcauccacg gcgagugcaa guacgugaag gagcugagag cccccagcug caucugccac      420

cccggcuacc acggcgagag augccacggc cugagccugc ccguggagaa cagacuguac      480

accuacgacc acaccaccau ccuggccgug guggccgugg ugcugagcag cgugugccug      540

cuggugaucg ugggccugcu gauguucaga uaccacagaa gaggcggcua cgacguggag      600

aacgaggaga aggugaagcu gggcaugacc aacagccacu gaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  1801
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt4)

<400>  1801
gggagaaagc uuaccaugug ggugaccaag cugcugcccg cccugcugcu gcagcacgug       60

cugcugcacc ugcugcugcu gcccaucgcc auccccuacg ccgagggcca gagaaagaga      120

agaaacacca uccacgaguu caagaagagc gccaagacca cccugaucaa gaucgacccc      180

gcccugaaga ucaagaccaa gaaggugaac accgccgacc agugcgccaa cagaugcacc      240

agaaacaagg gccugcccuu caccugcaag gccuucgugu ucgacaaggc cagaaagcag      300

ugccuguggu uccccuucaa cagcaugagc agcggcguga agaaggaguu cggccacgag      360

uucgaccugu acgagaacaa ggacuacauc agaaacugca ucaucggcaa gggcagaagc      420

uacaagggca ccgugagcau caccaagagc ggcaucaagu gccagcccug gagcagcaug      480

aucccccacg agcacagcuu ccugcccagc agcuacagag gcaaggaccu gcaggagaac      540

uacugcagaa accccagagg cgaggagggc ggccccuggu gcuucaccag caaccccgag      600

gugagauacg aggugugcga caucccccag ugcagcgagg uggagugcau gaccugcaac      660

ggcgagagcu acagaggccu gauggaccac accgagagcg gcaagaucug ccagagaugg      720

gaccaccaga ccccccacag acacaaguuc cugcccgaga gauaccccga caagggcuuc      780

gacgacaacu acugcagaaa ccccgacggc cagcccagac ccuggugcua cacccuggac      840

ccccacacca gaugggagua cugcgccauc aagaccugcg ccgacaacac caugaacgac      900

accgacgugc cccuggagac caccgagugc auccagggcc agggcgaggg cuacagaggc      960

accgugaaca ccaucuggaa cggcaucccc ugccagagau gggacagcca guacccccac     1020

gagcacgaca ugacccccga gaacuucaag ugcaaggacc ugagagagaa cuacugcaga     1080

aaccccgacg gcagcgagag ccccuggugc uucaccaccg accccaacau cagagugggc     1140

uacugcagcc agauccccaa cugcgacaug agccacggcc aggacugcua cagaggcaac     1200

ggcaagaacu acaugggcaa ccugagccag accagaagcg gccugaccug cagcaugugg     1260

gacaagaaca uggaggaccu gcacagacac aucuucuggg agcccgacgc cagcaagcug     1320

aacgagaacu acugcagaaa ccccgacgac gacgcccacg gccccuggug cuacaccggc     1380

aacccccuga uccccuggga cuacugcccc aucagcagau gcgagggcga caccaccccc     1440

accaucguga accuggacca ccccgugauc agcugcgcca agaccaagca gcugagagug     1500

gugaacggca uccccaccag aaccaacauc ggcuggaugg ugagccugag auacagaaac     1560

aagcacaucu gcggcggcag ccugaucaag gagagcuggg ugcugaccgc cagacagugc     1620

uuccccagca gagaccugaa ggacuacgag gccuggcugg gcauccacga cgugcacggc     1680

agaggcgacg agaagugcaa gcaggugcug aacgugagcc agcuggugua cggccccgag     1740

ggcagcgacc uggugcugau gaagcuggcc agacccgccg ugcuggacga cuucgugagc     1800

accaucgacc ugcccaacua cggcugcacc auccccgaga agaccagcug cagcguguac     1860

ggcuggggcu acaccggccu gaucaacuac gacggccugc ugagaguggc ccaccuguac     1920

aucaugggca acgagaagug cagccagcac cacagaggca aggugacccu gaacgagagc     1980

gagaucugcg ccggcgccga gaagaucggc agcggccccu gcgagggcga cuacggcggc     2040

ccccuggugu gcgagcagca caagaugaga auggugcugg gcgugaucgu gcccggcaga     2100

ggcugcgcca uccccaacag acccggcauc uucgugagag uggccuacua cgccaagugg     2160

auccacaaga ucauccugac cuacaaggug ccccagagcu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  1802
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt4)

<400>  1802
gggagaaagc uuaccauggc caaggccgcc gccaucggca ucgaccuggg caccaccuac       60

agcugcgugg gcguguucca gcacggcaag guggagauca ucgccaacga ccagggcaac      120

agaaccaccc ccagcuacgu ggccuucacc gacaccgaga gacugaucgg cgacgccgcc      180

aagaaccagg uggcccugaa cccccagaac accguguucg acgccaagag acugaucggc      240

agaaaguucg gcgaccccgu ggugcagagc gacaugaagc acuggcccuu ccaggugauc      300

aacgacggcg acaagcccaa ggugcaggug agcuacaagg gcgagaccaa ggccuucuac      360

cccgaggaga ucagcagcau ggugcugacc aagaugaagg agaucgccga ggccuaccug      420

ggcuaccccg ugaccaacgc cgugaucacc gugcccgccu acuucaacga cagccagaga      480

caggccacca aggacgccgg cgugaucgcc ggccugaacg ugcugagaau caucaacgag      540

cccaccgccg ccgccaucgc cuacggccug gacagaaccg gcaagggcga gagaaacgug      600

cugaucuucg accugggcgg cggcaccuuc gacgugagca uccugaccau cgacgacggc      660

aucuucgagg ugaaggccac cgccggcgac acccaccugg gcggcgagga cuucgacaac      720

agacugguga accacuucgu ggaggaguuc aagagaaagc acaagaagga caucagccag      780

aacaagagag ccgugagaag acugagaacc gccugcgaga gagccaagag aacccugagc      840

agcagcaccc aggccagccu ggagaucgac agccuguucg agggcaucga cuucuacacc      900

agcaucacca gagccagauu cgaggagcug ugcagcgacc uguucagaag cacccuggag      960

cccguggaga aggcccugag agacgccaag cuggacaagg cccagaucca cgaccuggug     1020

cuggugggcg gcagcaccag aauccccaag gugcagaagc ugcugcagga cuucuucaac     1080

ggcagagacc ugaacaagag caucaacccc gacgaggccg uggccuacgg cgccgccgug     1140

caggccgcca uccugauggg cgacaagagc gagaacgugc aggaccugcu gcugcuggac     1200

guggcccccc ugagccuggg ccuggagacc gccggcggcg ugaugaccgc ccugaucaag     1260

agaaacagca ccauccccac caagcagacc cagaucuuca ccaccuacag cgacaaccag     1320

cccggcgugc ugauccaggu guacgagggc gagagagcca ugaccaagga caacaaccug     1380

cugggcagau ucgagcugag cggcaucccc cccgccccca gaggcgugcc ccagaucgag     1440

gugaccuucg acaucgacgc caacggcauc cugaacguga ccgccaccga caagagcacc     1500

ggcaaggcca acaagaucac caucaccaac gacaagggca gacugagcaa ggaggagauc     1560

gagagaaugg ugcaggaggc cgagaaguac aaggccgagg acgaggugca gagagagaga     1620

gugagcgcca agaacgcccu ggagagcuac gccuucaaca ugaagagcgc cguggaggac     1680

gagggccuga agggcaagau cagcgaggcc gacaagaaga aggugcugga caagugccag     1740

gaggugauca gcuggcugga cgccaacacc cuggccgaga aggacgaguu cgagcacaag     1800

agaaaggagc uggagcaggu gugcaacccc aucaucagcg gccuguacca gggcgccggc     1860

ggccccggcc ccggcggcuu cggcgcccag ggccccaagg gcggcagcgg cagcggcccc     1920

accaucgagg agguggacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1803
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt4)

<400>  1803
gggagaaagc uuaccauggc caaggccgcc gccaucggca ucgaccuggg caccaccuac       60

agcugcgugg gcguguucca gcacggcaag guggagauca ucgccaacga ccagggcaac      120

agaaccaccc ccagcuacgu ggccuucacc gacaccgaga gacugaucgg cgacgccgcc      180

aagaaccagg uggcccugaa cccccagaac accguguucg acgccaagag acugaucggc      240

agaaaguucg gcgaccccgu ggugcagagc gacaugaagc acuggcccuu ccaggugauc      300

aacgacggcg acaagcccaa ggugcaggug agcuacaagg gcgagaccaa ggccuucuac      360

cccgaggaga ucagcagcau ggugcugacc aagaugaagg agaucgccga ggccuaccug      420

ggcuaccccg ugaccaacgc cgugaucacc gugcccgccu acuucaacga cagccagaga      480

caggccacca aggacgccgg cgugaucgcc ggccugaacg ugcugagaau caucaacgag      540

cccaccgccg ccgccaucgc cuacggccug gacagaaccg gcaagggcga gagaaacgug      600

cugaucuucg accugggcgg cggcaccuuc gacgugagca uccugaccau cgacgacggc      660

aucuucgagg ugaaggccac cgccggcgac acccaccugg gcggcgagga cuucgacaac      720

agacugguga accacuucgu ggaggaguuc aagagaaagc acaagaagga caucagccag      780

aacaagagag ccgugagaag acugagaacc gccugcgaga gagccaagag aacccugagc      840

agcagcaccc aggccagccu ggagaucgac agccuguucg agggcaucga cuucuacacc      900

agcaucacca gagccagauu cgaggagcug ugcagcgacc uguucagaag cacccuggag      960

cccguggaga aggcccugag agacgccaag cuggacaagg cccagaucca cgaccuggug     1020

cuggugggcg gcagcaccag aauccccaag gugcagaagc ugcugcagga cuucuucaac     1080

ggcagagacc ugaacaagag caucaacccc gacgaggccg uggccuacgg cgccgccgug     1140

caggccgcca uccugauggg cgacaagagc gagaacgugc aggaccugcu gcugcuggac     1200

guggcccccc ugagccuggg ccuggagacc gccggcggcg ugaugaccgc ccugaucaag     1260

agaaacagca ccauccccac caagcagacc cagaucuuca ccaccuacag cgacaaccag     1320

cccggcgugc ugauccaggu guacgagggc gagagagcca ugaccaagga caacaaccug     1380

cugggcagau ucgagcugag cggcaucccc cccgccccca gaggcgugcc ccagaucgag     1440

gugaccuucg acaucgacgc caacggcauc cugaacguga ccgccaccga caagagcacc     1500

ggcaaggcca acaagaucac caucaccaac gacaagggca gacugagcaa ggaggagauc     1560

gagagaaugg ugcaggaggc cgagaaguac aaggccgagg acgaggugca gagagagaga     1620

gugagcgcca agaacgcccu ggagagcuac gccuucaaca ugaagagcgc cguggaggac     1680

gagggccuga agggcaagau cagcgaggcc gacaagaaga aggugcugga caagugccag     1740

gaggugauca gcuggcugga cgccaacacc cuggccgaga aggacgaguu cgagcacaag     1800

agaaaggagc uggagcaggu gugcaacccc aucaucagcg gccuguacca gggcgccggc     1860

ggccccggcc ccggcggcuu cggcgcccag ggccccaagg gcggcagcgg cagcggcccc     1920

accaucgagg agguggacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1804
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt4)

<400>  1804
gggagaaagc uuaccauggc caccgccaag ggcaucgcca ucggcaucga ccugggcacc       60

accuacagcu gcgugggcgu guuccagcac ggcaaggugg agaucaucgc caacgaccag      120

ggcaacagaa ccacccccag cuacguggcc uucaccgaca ccgagagacu gaucggcgac      180

gccgccaaga accagguggc caugaacccc cagaacaccg uguucgacgc caagagacug      240

aucggcagaa aguucaacga ccccguggug caggccgaca ugaagcugug gcccuuccag      300

gugaucaacg agggcggcaa gcccaaggug cuggugagcu acaagggcga gaacaaggcc      360

uucuaccccg aggagaucag cagcauggug cugaccaagc ugaaggagac cgccgaggcc      420

uuccugggcc accccgugac caacgccgug aucaccgugc ccgccuacuu caacgacagc      480

cagagacagg ccaccaagga cgccggcgug aucgccggcc ugaacgugcu gagaaucauc      540

aacgagccca ccgccgccgc caucgccuac ggccuggaca agggcggcca gggcgagaga      600

cacgugcuga ucuucgaccu gggcggcggc accuucgacg ugagcauccu gaccaucgac      660

gacggcaucu ucgaggugaa ggccaccgcc ggcgacaccc accugggcgg cgaggacuuc      720

gacaacagac uggugagcca cuucguggag gaguucaaga gaaagcacaa gaaggacauc      780

agccagaaca agagagccgu gagaagacug agaaccgccu gcgagagagc caagagaacc      840

cugagcagca gcacccaggc caaccuggag aucgacagcc uguacgaggg caucgacuuc      900

uacaccagca ucaccagagc cagauucgag gagcugugcg ccgaccuguu cagaggcacc      960

cuggagcccg uggagaaggc ccugagagac gccaagaugg acaaggccaa gauccacgac     1020

aucgugcugg ugggcggcag caccagaauc cccaaggugc agagacugcu gcaggacuac     1080

uucaacggca gagaccugaa caagagcauc aaccccgacg aggccguggc cuacggcgcc     1140

gccgugcagg ccgccauccu gaugggcgac aagagcgaga aggugcagga ccugcugcug     1200

cuggacgugg ccccccugag ccugggccug gagaccgccg gcggcgugau gaccgcccug     1260

aucaagagaa acagcaccau ccccaccaag cagacccaga ucuucaccac cuacagcgac     1320

aaccagcccg gcgugcugau ccagguguac gagggcgaga gagccaugac caaggacaac     1380

aaccugcugg gcagauucga ccugaccggc aucccccccg cccccagagg cgugccccag     1440

aucgagguga ccuucgacau cgacgccaac ggcauccuga acgugaccgc caccgacaag     1500

agcaccggca aggugaacaa gaucaccauc accaacgaca agggcagacu gagcaaggag     1560

gagaucgaga gaauggugcu ggacgccgag aaguacaagg ccgaggacga ggugcagaga     1620

gagaagaucg ccgccaagaa cgcccuggag agcuacgccu ucaacaugaa gagcguggug     1680

agcgacgagg gccugaaggg caagaucagc gagagcgaca agaacaagau ccuggacaag     1740

ugcaacgagc ugcugagcug gcuggaggug aaccagcugg ccgagaagga cgaguucgac     1800

cacaagagaa aggagcugga gcagaugugc aaccccauca ucaccaagcu guaccagggc     1860

ggcugcaccg gccccgccug cggcaccggc uacgugcccg gcagacccgc caccggcccc     1920

accaucgagg agguggacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1805
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt4)

<400>  1805
gggagaaagc uuaccaugag cgccagaggc cccgccaucg gcaucgaccu gggcaccacc       60

uacagcugcg ugggcguguu ccagcacggc aagguggaga ucaucgccaa cgaccagggc      120

aacagaacca cccccagcua cguggccuuc accgacaccg agagacugau cggcgacgcc      180

gccaagaacc agguggccau gaaccccacc aacaccaucu ucgacgccaa gagacugauc      240

ggcagaaagu ucgaggacgc caccgugcag agcgacauga agcacuggcc cuucagagug      300

gugagcgagg gcggcaagcc caaggugcag guggaguaca agggcgagac caagaccuuc      360

uuccccgagg agaucagcag cauggugcug accaagauga aggagaucgc cgaggccuac      420

cugggcggca aggugcacag cgccgugauc accgugcccg ccuacuucaa cgacagccag      480

agacaggcca ccaaggacgc cggcaccauc accggccuga acgugcugag aaucaucaac      540

gagcccaccg ccgccgccau cgccuacggc cuggacaaga agggcugcgc cggcggcgag      600

aagaacgugc ugaucuucga ccugggcggc ggcaccuucg acgugagcau ccugaccauc      660

gaggacggca ucuucgaggu gaagagcacc gccggcgaca cccaccuggg cggcgaggac      720

uucgacaaca gaauggugag ccaccuggcc gaggaguuca agagaaagca caagaaggac      780

aucggcccca acaagagagc cgugagaaga cugagaaccg ccugcgagag agccaagaga      840

acccugagca gcagcaccca ggccagcauc gagaucgaca gccuguacga gggcguggac      900

uucuacacca gcaucaccag agccagauuc gaggagcuga acgccgaccu guucagaggc      960

acccuggagc ccguggagaa ggcccugaga gacgccaagc uggacaaggg ccagauccag     1020

gagaucgugc uggugggcgg cagcaccaga auccccaaga uccagaagcu gcugcaggac     1080

uucuucaacg gcaaggagcu gaacaagagc aucaaccccg acgaggccgu ggccuacggc     1140

gccgccgugc aggccgccau ccugaucggc gacaagagcg agaacgugca ggaccugcug     1200

cugcuggacg ugaccccccu gagccugggc aucgagaccg ccggcggcgu gaugaccccc     1260

cugaucaaga gaaacaccac cauccccacc aagcagaccc agaccuucac caccuacagc     1320

gacaaccaga gcagcgugcu ggugcaggug uacgagggcg agagagccau gaccaaggac     1380

aacaaccugc ugggcaaguu cgaccugacc ggcauccccc ccgcccccag aggcgugccc     1440

cagaucgagg ugaccuucga caucgacgcc aacggcaucc ugaacgugac cgccgccgac     1500

aagagcaccg gcaaggagaa caagaucacc aucaccaacg acaagggcag acugagcaag     1560

gacgacaucg acagaauggu gcaggaggcc gagagauaca agagcgagga cgaggccaac     1620

agagacagag uggccgccaa gaacgcccug gagagcuaca ccuacaacau caagcagacc     1680

guggaggacg agaagcugag aggcaagauc agcgagcagg acaagaacaa gauccuggac     1740

aagugccagg aggugaucaa cuggcuggac agaaaccaga uggccgagaa ggacgaguac     1800

gagcacaagc agaaggagcu ggagagagug ugcaacccca ucaucagcaa gcuguaccag     1860

ggcggccccg gcggcggcag cggcggcggc ggcagcggcg ccagcggcgg ccccaccauc     1920

gaggaggugg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  1806
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt4)

<400>  1806
gggagaaagc uuaccaugag cguggugggc aucgaccugg gcuuccagag cugcuacgug       60

gccguggcca gagccggcgg caucgagacc aucgccaacg aguacagcga cagaugcacc      120

cccgccugca ucagcuucgg ccccaagaac agaagcaucg gcgccgccgc caagagccag      180

gugaucagca acgccaagaa caccgugcag ggcuucaaga gauuccacgg cagagccuuc      240

agcgaccccu ucguggaggc cgagaagagc aaccuggccu acgacaucgu gcagcugccc      300

accggccuga ccggcaucaa ggugaccuac auggaggagg agagaaacuu caccaccgag      360

caggugaccg ccaugcugcu gagcaagcug aaggagaccg ccgagagcgu gcugaagaag      420

cccguggugg acugcguggu gagcgugccc ugcuucuaca ccgacgccga gagaagaagc      480

gugauggacg ccacccagau cgccggccug aacugccuga gacugaugaa cgagaccacc      540

gccguggccc uggccuacgg caucuacaag caggaccugc ccgcccugga ggagaagccc      600

agaaacgugg uguucgugga caugggccac agcgccuacc aggugagcgu gugcgccuuc      660

aacagaggca agcugaaggu gcuggccacc gccuucgaca ccacccuggg cggcagaaag      720

uucgacgagg ugcuggugaa ccacuucugc gaggaguucg gcaagaagua caagcuggac      780

aucaagagca agaucagagc ccugcugaga cugagccagg agugcgagaa gcugaagaag      840

cugaugagcg ccaacgccag cgaccugccc cugagcaucg agugcuucau gaacgacgug      900

gacgugagcg gcaccaugaa cagaggcaag uuccuggaga ugugcaacga ccugcuggcc      960

agaguggagc ccccccugag aagcgugcug gagcagacca agcugaagaa ggaggacauc     1020

uacgccgugg agaucguggg cggcgccacc agaauccccg ccgugaagga gaagaucagc     1080

aaguucuucg gcaaggagcu gagcaccacc cugaacgccg acgaggccgu gaccagaggc     1140

ugcgcccugc agugcgccau ccugagcccc gccuucaagg ugagagaguu cagcaucacc     1200

gacguggugc ccuaccccau cagccugaga uggaacagcc ccgccgagga gggcagcagc     1260

gacugcgagg uguucagcaa gaaccacgcc gcccccuuca gcaaggugcu gaccuucuac     1320

agaaaggagc ccuucacccu ggaggccuac uacagcagcc cccaggaccu gcccuacccc     1380

gaccccgcca ucgcccaguu cagcgugcag aaggugaccc cccagagcga cggcagcagc     1440

agcaagguga aggugaaggu gagagugaac gugcacggca ucuucagcgu gagcagcgcc     1500

agccuggugg aggugcacaa gagcgaggag aacgaggagc ccauggagac cgaccagaac     1560

gccaaggagg aggagaagau gcagguggac caggaggagc cccacgugga ggagcagcag     1620

cagcagaccc ccgccgagaa caaggccgag agcgaggaga uggagaccag ccaggccggc     1680

agcaaggaca agaagaugga ccagcccccc caggccaaga aggccaaggu gaagaccagc     1740

accguggacc ugcccaucga gaaccagcug cuguggcaga ucgacagaga gaugcugaac     1800

cuguacaucg agaacgaggg caagaugauc augcaggaca agcuggagaa ggagagaaac     1860

gacgccaaga acgccgugga ggaguacgug uacgagauga gagacaagcu gagcggcgag     1920

uacgagaagu ucgugagcga ggacgacaga aacagcuuca cccugaagcu ggaggacacc     1980

gagaacuggc uguacgagga cggcgaggac cagcccaagc agguguacgu ggacaagcug     2040

gccgagcuga agaaccuggg ccagcccauc aagaucagau uccaggagag cgaggagaga     2100

cccaagcugu ucgaggagcu gggcaagcag auccagcagu acaugaagau caucagcagc     2160

uucaagaaca aggaggacca guacgaccac cuggacgccg ccgacaugac caagguggag     2220

aagagcacca acgaggccau ggaguggaug aacaacaagc ugaaccugca gaacaagcag     2280

agccugacca uggaccccgu ggugaagagc aaggagaucg aggccaagau caaggagcug     2340

accagcaccu gcagccccau caucagcaag cccaagccca agguggagcc ccccaaggag     2400

gagcagaaga acgccgagca gaacggcccc guggacggcc agggcgacaa ccccggcccc     2460

caggccgccg agcagggcac cgacaccgcc gugcccagcg acagcgacaa gaagcugccc     2520

gagauggaca ucgacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  1807
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt4)

<400>  1807
gggagaaagc uuaccaugag cguggugggc aucgaccugg gcuuccugaa cugcuacauc       60

gccguggcca gaagcggcgg caucgagacc aucgccaacg aguacagcga cagaugcacc      120

cccgccugca ucagccuggg cagcagaacc agagccaucg gcaacgccgc caagagccag      180

aucgugacca acgugagaaa caccauccac ggcuucaaga agcugcacgg cagaagcuuc      240

gacgacccca ucgugcagac cgagagaauc agacugcccu acgagcugca gaagaugccc      300

aacggcagcg ccggcgugaa ggugagauac cuggaggagg agagacccuu cgccaucgag      360

caggugaccg gcaugcugcu ggccaagcug aaggagacca gcgagaacgc ccugaagaag      420

cccguggccg acugcgugau cagcaucccc agcuucuuca ccgacgccga gagaagaagc      480

gugauggccg ccgcccaggu ggccggccug aacugccuga gacugaugaa cgagaccacc      540

gccguggccc uggccuacgg caucuacaag caggaccugc ccccccugga cgagaagccc      600

agaaacgugg uguucaucga caugggccac agcgccuacc aggugcuggu gugcgccuuc      660

aacaagggca agcugaaggu gcuggccacc accuucgacc ccuaccuggg cggcagaaac      720

uucgacgagg cccuggugga cuacuucugc gacgaguuca agaccaagua caagaucaac      780

gugaaggaga acagcagagc ccugcugaga cuguaccagg agugcgagaa gcugaagaag      840

cugaugagcg ccaacgccag cgaccugccc cugaacaucg agugcuucau gaacgaccug      900

gacgugagca gcaagaugaa cagagcccag uucgagcagc ugugcgccag ccugcuggcc      960

agaguggagc ccccccugaa ggccgugaug gagcaggcca accugcagag agaggacauc     1020

agcagcaucg agaucguggg cggcgccacc agaauccccg ccgugaagga gcagaucacc     1080

aaguucuucc ugaaggacau cagcaccacc cugaacgccg acgaggccgu ggccagaggc     1140

ugcgcccugc agugcgccau ccugagcccc gccuucaagg ugagagaguu cagcaucacc     1200

gaccuggugc ccuacagcau cacccugaga uggaagacca gcuucgagga cggcagcggc     1260

gagugcgagg uguucugcaa gaaccacccc gcccccuuca gcaaggugau caccuuccac     1320

aagaaggagc ccuucgagcu ggaggccuuc uacaccaacc ugcacgaggu gcccuacccc     1380

gacgccagaa ucggcagcuu caccauccag aacguguucc cccagagcga cggcgacagc     1440

agcaagguga aggugaaggu gagagugaac auccacggca ucuucagcgu ggccagcgcc     1500

agcgugaucg agaagcagaa ccuggagggc gaccacagcg acgcccccau ggagaccgag     1560

accagcuuca agaacgagaa caaggacaac auggacaaga ugcaggugga ccaggaggag     1620

ggccaccaga agugccacgc cgagcacacc cccgaggagg agaucgacca caccggcgcc     1680

aagaccaaga gcgccgugag cgacaagcag gacagacuga accagacccu gaagaagggc     1740

aaggugaaga gcaucgaccu gcccauccag agcagccugu gcagacagcu gggccaggac     1800

cugcugaaca gcuacaucga gaacgagggc aagaugauca ugcaggacaa gcuggagaag     1860

gagagaaacg acgccaagaa cgccguggag gaguacgugu acgacuucag agacagacug     1920

ggcaccgugu acgagaaguu caucaccccc gaggaccuga gcaagcugag cgccgugcug     1980

gaggacaccg agaacuggcu guacgaggac ggcgaggacc agcccaagca gguguacgug     2040

gacaagcugc aggagcugaa gaaguacggc cagcccaucc agaugaagua cauggagcac     2100

gaggagagac ccaaggcccu gaacgaccug ggcaagaaga uccagcuggu gaugaaggug     2160

aucgaggccu acagaaacaa ggacgagaga uacgaccacc uggaccccac cgagauggag     2220

aagguggaga agugcaucag cgacgccaug agcuggcuga acagcaagau gaacgcccag     2280

aacaagcuga gccugaccca ggaccccgug gugaagguga gcgagaucgu ggccaagagc     2340

aaggagcugg acaacuucug caaccccauc aucuacaagc ccaagcccaa ggccgaggug     2400

cccgaggaca agcccaaggc caacagcgag cacaacggcc ccauggacgg ccagagcggc     2460

accgagacca agagcgacag caccaaggac agcagccagc acaccaagag cagcggcgag     2520

auggaggugg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  1808
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt4)

<400>  1808
gggagaaagc uuaccaugaa gcugagccug guggccgcca ugcugcugcu gcugagcgcc       60

gccagagccg aggaggagga caagaaggag gacgugggca ccgugguggg caucgaccug      120

ggcaccaccu acagcugcgu gggcguguuc aagaacggca gaguggagau caucgccaac      180

gaccagggca acagaaucac ccccagcuac guggccuuca cccccgaggg cgagagacug      240

aucggcgacg ccgccaagaa ccagcugacc agcaaccccg agaacaccgu guucgacgcc      300

aagagacuga ucggcagaac cuggaacgac cccagcgugc agcaggacau caaguuccug      360

cccuucaagg ugguggagaa gaagaccaag cccuacaucc agguggacau cggcggcggc      420

cagaccaaga ccuucgcccc cgaggagauc agcgccaugg ugcugaccaa gaugaaggag      480

accgccgagg ccuaccuggg caagaaggug acccacgccg uggugaccgu gcccgccuac      540

uucaacgacg cccagagaca ggccaccaag gacgccggca ccaucgccgg ccugaacgug      600

augagaauca ucaacgagcc caccgccgcc gccaucgccu acggccugga caagagagag      660

ggcgagaaga acauccuggu guucgaccug ggcggcggca ccuucgacgu gagccugcug      720

accaucgaca acggcguguu cgagguggug gccaccaacg gcgacaccca ccugggcggc      780

gaggacuucg accagagagu gauggagcac uucaucaagc uguacaagaa gaagaccggc      840

aaggacguga gaaaggacaa cagagccgug cagaagcuga gaagagaggu ggagaaggcc      900

aagagagccc ugagcagcca gcaccaggcc agaaucgaga ucgagagcuu cuacgagggc      960

gaggacuuca gcgagacccu gaccagagcc aaguucgagg agcugaacau ggaccuguuc     1020

agaagcacca ugaagcccgu gcagaaggug cuggaggaca gcgaccugaa gaagagcgac     1080

aucgacgaga ucgugcuggu gggcggcagc accagaaucc ccaagaucca gcagcuggug     1140

aaggaguucu ucaacggcaa ggagcccagc agaggcauca accccgacga ggccguggcc     1200

uacggcgccg ccgugcaggc cggcgugcug agcggcgacc aggacaccgg cgaccuggug     1260

cugcuggacg ugugcccccu gacccugggc aucgagaccg ugggcggcgu gaugaccaag     1320

cugaucccca gaaacaccgu ggugcccacc aagaagagcc agaucuucag caccgccagc     1380

gacaaccagc ccaccgugac caucaaggug uacgagggcg agagaccccu gaccaaggac     1440

aaccaccugc ugggcaccuu cgaccugacc ggcauccccc ccgcccccag aggcgugccc     1500

cagaucgagg ugaccuucga gaucgacgug aacggcaucc ugagagugac cgccgaggac     1560

aagggcaccg gcaacaagaa caagaucacc aucaccaacg accagaacag acugaccccc     1620

gaggagaucg agagaauggu gaacgacgcc gagaaguucg ccgaggagga caagaagcug     1680

aaggagagaa ucgacaccag aaacgagcug gagagcuacg ccuacagccu gaagaaccag     1740

aucggcgaca aggagaagcu gggcggcaag cugagcagcg aggacaagga gaccauggag     1800

aaggccgugg aggagaagau cgaguggcug gagagccacc aggacgccga caucgaggac     1860

uucaaggcca agaagaagga gcuggaggag aucgugcagc ccaucaucag caagcuguac     1920

ggcagcgccg gccccccccc caccggcgag gaggacaccg ccgagaagga cgagcuguga     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  1809
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt4)

<400>  1809
gggagaaagc uuaccaugca ggcccccaga gagcuggccg ugggcaucga ccugggcacc       60

accuacagcu gcgugggcgu guuccagcag ggcagagugg agauccuggc caacgaccag      120

ggcaacagaa ccacccccag cuacguggcc uucaccgaca ccgagagacu ggugggcgac      180

gccgccaaga gccaggccgc ccugaacccc cacaacaccg uguucgacgc caagagacug      240

aucggcagaa aguucgccga caccaccgug cagagcgaca ugaagcacug gcccuucaga      300

guggugagcg agggcggcaa gcccaaggug agagugugcu acagaggcga ggacaagacc      360

uucuaccccg aggagaucag cagcauggug cugagcaaga ugaaggagac cgccgaggcc      420

uaccugggcc agcccgugaa gcacgccgug aucaccgugc ccgccuacuu caacgacagc      480

cagagacagg ccaccaagga cgccggcgcc aucgccggcc ugaacgugcu gagaaucauc      540

aacgagccca ccgccgccgc caucgccuac ggccuggaca gaagaggcgc cggcgagaga      600

aacgugcuga ucuucgaccu gggcggcggc accuucgacg ugagcgugcu gagcaucgac      660

gccggcgugu ucgaggugaa ggccaccgcc ggcgacaccc accugggcgg cgaggacuuc      720

gacaacagac uggugaacca cuucauggag gaguucagaa gaaagcacgg caaggaccug      780

agcggcaaca agagagcccu gagaagacug agaaccgccu gcgagagagc caagagaacc      840

cugagcagca gcacccaggc cacccuggag aucgacagcc uguucgaggg cguggacuuc      900

uacaccagca ucaccagagc cagauucgag gagcugugca gcgaccuguu cagaagcacc      960

cuggagcccg uggagaaggc ccugagagac gccaagcugg acaaggccca gauccacgac     1020

guggugcugg ugggcggcag caccagaauc cccaaggugc agaagcugcu gcaggacuuc     1080

uucaacggca aggagcugaa caagagcauc aaccccgacg aggccguggc cuacggcgcc     1140

gccgugcagg ccgccgugcu gaugggcgac aagugcgaga aggugcagga ccugcugcug     1200

cuggacgugg ccccccugag ccugggccug gagaccgccg gcggcgugau gaccacccug     1260

auccagagaa acgccaccau ccccaccaag cagacccaga ccuucaccac cuacagcgac     1320

aaccagcccg gcguguucau ccagguguac gagggcgaga gagccaugac caaggacaac     1380

aaccugcugg gcagauucga gcugagcggc aucccccccg cccccagagg cgugccccag     1440

aucgagguga ccuucgacau cgacgccaac ggcauccuga gcgugaccgc caccgacaga     1500

agcaccggca aggccaacaa gaucaccauc accaacgaca agggcagacu gagcaaggag     1560

gagguggaga gaauggugca cgaggccgag caguacaagg ccgaggacga ggcccagaga     1620

gacagagugg ccgccaagaa cagccuggag gcccacgugu uccacgugaa gggcagccug     1680

caggaggaga gccugagaga caagaucccc gaggaggaca gaagaaagau gcaggacaag     1740

ugcagagagg ugcuggccug gcuggagcac aaccagcugg ccgagaagga ggaguacgag     1800

caccagaaga gagagcugga gcagaucugc agacccaucu ucagcagacu guacggcggc     1860

cccggcgugc ccggcggcag cagcugcggc acccaggcca gacagggcga ccccagcacc     1920

ggccccauca ucgaggaggu ggacugagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  1810
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt4)

<400>  1810
gggagaaagc uuaccaugca ggcccccaga gagcuggccg ugggcaucga ccugggcacc       60

accuacagcu gcgugggcgu guuccagcag ggcagagugg agauccuggc caacgaccag      120

ggcaacagaa ccacccccag cuacguggcc uucaccgaca ccgagagacu ggugggcgac      180

gccgccaaga gccaggccgc ccugaacccc cacaacaccg uguucgacgc caagagacug      240

aucggcagaa aguucgccga caccaccgug cagagcgaca ugaagcacug gcccuuccag      300

guggugagcg agggcggcaa gcccaaggug agagugugcu acagaggcga ggacaagacc      360

uucuaccccg aggagaucag cagcauggug cugagcaaga ugaaggagac cgccgaggcc      420

uaccugggcc agcccgugaa gcacgccgug aucaccgugc ccaccuacuu cagcaacagc      480

cagagacagg ccaccaagga cgccggcgcc aucgccggcc ugaaggugcu gcccaucauc      540

aacgaggcca ccgccgccgc caucgccuac ggccuggaca gaagaggcgc cggcaagaga      600

aacgugcuga ucuucgaccu gggcggcggc accuucgacg ugagcgugcu gagcaucgac      660

gccggcgugu ucgaggugaa ggccaccgcc ggcgacaccc accugggcgg cgaggacuuc      720

gacaacagac uggugaacca cuucauggag gaguucagaa gaaagcacgg caaggaccug      780

agcggcaaca agagagcccu gagaagacug agaaccgccu gcgagagagc caagagaacc      840

cccagcagca gcacccaggc cacccuggag aucgacagcc uguucgaggg cguggacuuc      900

uacaagagca ucaccagagc cagauucgag gagcugugca gcgaccuguu cagaagcacc      960

cuggagcccg uggagaaggc ccugagagac gccaagcugg acaaggccca gauccacgac     1020

uucgugcugg gcggcggccu gcacagccac ccccagggcg ccgagguggc cgccggccug     1080

cugcagagac agggcgccga gcaggagcac cagcccugag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  1811
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt4)

<400>  1811
gggagaaagc uuaccaugag caagggcccc gccgugggca ucgaccuggg caccaccuac       60

agcugcgugg gcguguucca gcacggcaag guggagauca ucgccaacga ccagggcaac      120

agaaccaccc ccagcuacgu ggccuucacc gacaccgaga gacugaucgg cgacgccgcc      180

aagaaccagg uggccaugaa ccccaccaac accguguucg acgccaagag acugaucggc      240

agaagauucg acgacgccgu ggugcagagc gacaugaagc acuggcccuu caugguggug      300

aacgacgccg gcagacccaa ggugcaggug gaguacaagg gcgagaccaa gagcuucuac      360

cccgaggagg ugagcagcau ggugcugacc aagaugaagg agaucgccga ggccuaccug      420

ggcaagaccg ugaccaacgc cguggugacc gugcccgccu acuucaacga cagccagaga      480

caggccacca aggacgccgg caccaucgcc ggccugaacg ugcugagaau caucaacgag      540

cccaccgccg ccgccaucgc cuacggccug gacaagaagg ugggcgccga gagaaacgug      600

cugaucuucg accugggcgg cggcaccuuc gacgugagca uccugaccau cgaggacggc      660

aucuucgagg ugaagagcac cgccggcgac acccaccugg gcggcgagga cuucgacaac      720

agaaugguga accacuucau cgccgaguuc aagagaaagc acaagaagga caucagcgag      780

aacaagagag ccgugagaag acugagaacc gccugcgaga gagccaagag aacccugagc      840

agcagcaccc aggccagcau cgagaucgac agccuguacg agggcaucga cuucuacacc      900

agcaucacca gagccagauu cgaggagcug aacgccgacc uguucagagg cacccuggac      960

cccguggaga aggcccugag agacgccaag cuggacaaga gccagaucca cgacaucgug     1020

cuggugggcg gcagcaccag aauccccaag auccagaagc ugcugcagga cuucuucaac     1080

ggcaaggagc ugaacaagag caucaacccc gacgaggccg uggccuacgg cgccgccgug     1140

caggccgcca uccugagcgg cgacaagagc gagaacgugc aggaccugcu gcugcuggac     1200

gugacccccc ugagccuggg caucgagacc gccggcggcg ugaugaccgu gcugaucaag     1260

agaaacacca ccauccccac caagcagacc cagaccuuca ccaccuacag cgacaaccag     1320

cccggcgugc ugauccaggu guacgagggc gagagagcca ugaccaagga caacaaccug     1380

cugggcaagu ucgagcugac cggcaucccc cccgccccca gaggcgugcc ccagaucgag     1440

gugaccuucg acaucgacgc caacggcauc cugaacguga gcgccgugga caagagcacc     1500

ggcaaggaga acaagaucac caucaccaac gacaagggca gacugagcaa ggaggacauc     1560

gagagaaugg ugcaggaggc cgagaaguac aaggccgagg acgagaagca gagagacaag     1620

gugagcagca agaacagccu ggagagcuac gccuucaaca ugaaggccac cguggaggac     1680

gagaagcugc agggcaagau caacgacgag gacaagcaga agauccugga caagugcaac     1740

gagaucauca acuggcugga caagaaccag accgccgaga aggaggaguu cgagcaccag     1800

cagaaggagc uggagaaggu gugcaacccc aucaucacca agcuguacca gagcgccggc     1860

ggcaugcccg gcggcaugcc cggcggcuuc cccggcggcg gcgccccccc cagcggcggc     1920

gccagcagcg gccccaccau cgaggaggug gacugaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  1812
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt4)

<400>  1812
gggagaaagc uuaccaugau cagcgccagc agagccgccg ccgccagacu ggugggcgcc       60

gccgccagca gaggccccac cgccgccaga caccaggaca gcuggaacgg ccugagccac      120

gaggccuuca gacuggugag cagaagagac uacgccagcg aggccaucaa gggcgccgug      180

gugggcaucg accugggcac caccaacagc ugcguggccg ugauggaggg caagcaggcc      240

aaggugcugg agaacgccga gggcgccaga accaccccca gcgugguggc cuucaccgcc      300

gacggcgaga gacugguggg caugcccgcc aagagacagg ccgugaccaa ccccaacaac      360

accuucuacg ccaccaagag acugaucggc agaagauacg acgaccccga ggugcagaag      420

gacaucaaga acgugcccuu caagaucgug agagccagca acggcgacgc cuggguggag      480

gcccacggca agcuguacag ccccagccag aucggcgccu ucgugcugau gaagaugaag      540

gagaccgccg agaacuaccu gggccacacc gccaagaacg ccgugaucac cgugcccgcc      600

uacuucaacg acagccagag acaggccacc aaggacgccg gccagaucag cggccugaac      660

gugcugagag ugaucaacga gcccaccgcc gccgcccugg ccuacggccu ggacaagagc      720

gaggacaagg ugaucgccgu guacgaccug ggcggcggca ccuucgacau cagcauccug      780

gagauccaga agggcguguu cgaggugaag agcaccaacg gcgacaccuu ccugggcggc      840

gaggacuucg accaggcccu gcugagacac aucgugaagg aguucaagag agagaccggc      900

guggaccuga ccaaggacaa cauggcccug cagagaguga gagaggccgc cgagaaggcc      960

aagugcgagc ugagcagcag cgugcagacc gacaucaacc ugcccuaccu gaccauggac     1020

agcagcggcc ccaagcaccu gaacaugaag cugaccagag cccaguucga gggcaucgug     1080

accgaccuga ucagaagaac caucgccccc ugccagaagg ccaugcagga cgccgaggug     1140

agcaagagcg acaucggcga ggugauccug gugggcggca ugaccagaau gcccaaggug     1200

cagcagaccg ugcaggaccu guucggcaga gcccccagca aggccgugaa ccccgacgag     1260

gccguggcca ucggcgccgc cauccagggc ggcgugcugg ccggcgacgu gaccgacgug     1320

cugcugcugg acgugacccc ccugagccug ggcaucgaga cccugggcgg cguguucacc     1380

aagcugauca acagaaacac caccaucccc accaagaaga gccagguguu cagcaccgcc     1440

gccgacggcc agacccaggu ggagaucaag gugugccagg gcgagagaga gauggccggc     1500

gacaacaagc ugcugggcca guucacccug aucggcaucc cccccgcccc cagaggcgug     1560

ccccagaucg aggugaccuu cgacaucgac gccaacggca ucgugcacgu gagcgccaag     1620

gacaagggca ccggcagaga gcagcagauc gugauccaga gcagcggcgg ccugagcaag     1680

gacgacaucg agaacauggu gaagaacgcc gagaaguacg ccgaggagga cagaagaaag     1740

aaggagagag uggaggccgu gaacauggcc gagggcauca uccacgacac cgagaccaag     1800

auggaggagu ucaaggacca gcugcccgcc gacgagugca acaagcugaa ggaggagauc     1860

agcaagauga gagagcugcu ggccagaaag gacagcgaga ccggcgagaa caucagacag     1920

gccgccagca gccugcagca ggccagccug aagcuguucg agauggccua caagaagaug     1980

gccagcgaga gagagggcag cggcagcagc ggcaccggcg agcagaagga ggaccagaag     2040

gaggagaagc agugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  1813
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt4)

<400>  1813
gggagaaagc uuaccauggc cgacaaggag gccggcggca gcgacggccc cagagagacc       60

gcccccacca gcgccuacag cagccccgcc agaagccugg gcgacaccgg caucaccccc      120

cugagcccca gccacaucgu gaacgacacc gacagcaacg ugagcgagca gcagagcuuc      180

cugguggugg uggccgugga cuucggcacc accagcagcg gcuacgccua cagcuucacc      240

aaggagcccg agugcaucca cgugaugaga agaugggagg gcggcgaccc cggcgugagc      300

aaccagaaga cccccaccac cauccugcug acccccgaga gaaaguucca cagcuucggc      360

uacgccgcca gagacuucua ccacgaccug gaccccaacg aggccaagca guggcuguac      420

cuggagaagu ucaagaugaa gcugcacacc accggcgacc ugaccaugga caccgaccug      480

accgccgcca acggcaagaa ggugaaggcc cuggagaucu ucgccuacgc ccugcaguac      540

uucaaggagc aggcccugaa ggagcugagc gaccaggccg gcagcgaguu cgagaacagc      600

gacgugagau gggugaucac cgugcccgcc aucuggaagc agcccgccaa gcaguucaug      660

agacaggccg ccuaccaggc cggccuggcc agccccgaga acagcgagca gcugaucauc      720

gcccuggagc ccgaggccgc cagcaucuac ugcagaaagc ugagacugca ccagaugauc      780

gagcugagca gcaaggccgc cgugaacggc uacagcggca gcgacaccgu gggcgccggc      840

uucacccagg ccaaggagca caucagaaga aacagacaga gcagaaccuu ccugguggag      900

aacgugaucg gcgagaucug gagcgagcug gaggagggcg acaaguacgu ggugguggac      960

agcggcggcg gcaccgugga ccugaccgug caccagauca gacugcccga gggccaccug     1020

aaggagcugu acaaggccac cggcggcccc uacggcagcc ugggcgugga cuacgaguuc     1080

gagaagcugc uguacaagau cuucggcgag gacuucaucg agcaguucaa gaucaagaga     1140

cccgccgccu ggguggaccu gaugaucgcc uucgagagca gaaagagagc cgccgccccc     1200

gacagaacca acccccugaa caucacccug cccuucagcu ucaucgacua cuacaagaag     1260

uucagaggcc acagcgugga gcacgcccug agaaagagca acguggacuu cgugaagugg     1320

agcagccagg gcaugcugag aaugagcccc gacgccauga acgcccuguu caagcccacc     1380

aucgacagca ucaucgagca ccugagagac cuguuccaga agcccgaggu gagcaccgug     1440

aaguuccugu uccugguggg cggcuucgcc gaggcccccc ugcugcagca ggccgugcag     1500

gccgccuucg gcgaccagug cagaaucauc aucccccagg acgugggccu gaccauccug     1560

aagggcgccg ugcuguucgg ccuggacccc gccgugauca aggugagaag aagcccccug     1620

accuacggcg ugggcgugcu gaacagauac guggagggca agcacccccc cgagaagcug     1680

cuggugaagg acggcaccag auggugcacc gacguguucg acaaguucau cagcgccgac     1740

cagagcgugg cccugggcga gcuggugaag agaagcuaca cccccgccaa gcccagccag     1800

cuggugaucg ugaucaacau cuacagcagc gagcacgaca acgugagcuu caucaccgac     1860

cccggcguga agaagugcgg cacccugaga cuggaccuga ccggcaccag cggcaccgcc     1920

gugcccgcca gaagagagau ccagacccug augcaguucg gcgacaccga gaucaaggcc     1980

accgccaucg acaucgccac cagcaagagc gugaaggugg gcaucgacuu ccugaacuac     2040

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  1814
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt4)

<400>  1814
gggagaaagc uuaccaugcu ggccgugccc gagaugggcc ugcagggccu guacaucggc       60

agcagccccg agagaagccc cgugcccagc ccccccggca gccccagaac ccaggagagc      120

ugcggcaucg ccccccugac ccccagccag agccccaagc ccgaggugag agccccccag      180

caggccagcu ucagcguggu gguggccauc gacuucggca ccaccagcag cggcuacgcc      240

uucagcuucg ccagcgaccc cgaggccauc cacaugauga gaaaguggga gggcggcgac      300

cccggcgugg cccaccagaa gacccccacc ugccugcugc ugacccccga gggcgccuuc      360

cacagcuucg gcuacaccgc cagagacuac uaccacgacc uggaccccga ggaggccaga      420

gacuggcugu acuucgagaa guucaagaug aagauccaca gcgccaccga ccugacccug      480

aagacccagc uggaggccgu gaacggcaag accaugcccg cccuggaggu guucgcccac      540

gcccugagau ucuucagaga gcacgcccug caggagcuga gagagcagag ccccagccug      600

cccgagaagg acaccgugag augggugcug accgugcccg ccaucuggaa gcagcccgcc      660

aagcaguuca ugagagaggc cgccuaccug gccggccugg ugagcagaga gaacgccgag      720

cagcugcuga ucgcccugga gcccgaggcc gccagcgugu acugcagaaa gcugagacug      780

caccagcugc uggaccugag cggcagagcc cccggcggcg gcagacuggg cgagagaaga      840

agcaucgaca gcagcuucag acaggccaga gagcagcuga gaagaagcag acacagcaga      900

accuuccugg uggagagcgg cgugggcgag cugugggccg agaugcaggc cggcgacaga      960

uacguggugg ccgacugcgg cggcggcacc guggaccuga ccgugcacca gcuggagcag     1020

ccccacggca cccugaagga gcuguacaag gccagcggcg gccccuacgg cgccgugggc     1080

guggaccugg ccuucgagca gcugcugugc agaaucuucg gcgaggacuu caucgccacc     1140

uucaagagac agagacccgc cgccugggug gaccugacca ucgccuucga ggccagaaag     1200

agaaccgccg gcccccacag agccggcgcc cugaacauca gccugcccuu cagcuucauc     1260

gacuucuaca gaaagcagag aggccacaac guggagaccg cccugagaag aagcagcgug     1320

aacuucguga aguggagcag ccagggcaug cugagaauga gcugcgaggc caugaacgag     1380

cuguuccagc ccaccgugag cggcaucauc cagcacaucg aggcccugcu ggccagaccc     1440

gaggugcagg gcgugaagcu gcuguuccug gugggcggcu ucgccgagag cgccgugcug     1500

cagcacgccg ugcaggccgc ccugggcgcc agaggccuga gagugguggu gccccacgac     1560

gugggccuga ccauccugaa gggcgccgug cuguucggcc aggcccccgg cguggugaga     1620

gugagaagaa gcccccugac cuacggcgug ggcgugcuga acagauucgu gcccggcaga     1680

cacccccccg agaagcugcu ggugagagac ggcagaagau ggugcaccga cguguucgag     1740

agauucgugg ccgccgagca gagcguggcc cugggcgagg aggugagaag aagcuacugc     1800

cccgccagac ccggccagag aagagugcug aucaaccugu acugcugcgc cgccgaggac     1860

gccagauuca ucaccgaccc cggcgugaga aagugcggcg cccugagccu ggagcuggag     1920

cccgccgacu gcggccagga caccgccggc gccccccccg gcagaagaga gaucagagcc     1980

gccaugcagu ucggcgacac cgagaucaag gugaccgccg uggacgugag caccaacaga     2040

agcgugagag ccagcaucga cuuccugagc aacugaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  1815
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt4)

<400>  1815
gggagaaagc uuaccauggc cagagagaug accauccugg gcagcgccgu gcugacccug       60

cugcuggccg gcuaccuggc ccagcaguac cugccccugc ccacccccaa ggugaucggc      120

aucgaccugg gcaccaccua cugcagcgug ggcguguucu uccccggcac cggcaaggug      180

aaggugaucc ccgacgagaa cggccacauc agcaucccca gcauggugag cuucaccgac      240

aacgacgugu acgugggcua cgagagcgug gagcuggccg acagcaaccc ccagaacacc      300

aucuacgacg ccaagagauu caucggcaag aucuucaccg ccgaggagcu ggaggccgag      360

aucggcagau accccuucaa ggugcugaac aagaacggca ugguggaguu cagcgugacc      420

agcaacgaga ccaucaccgu gagccccgag uacgugggca gcagacugcu gcugaagcug      480

aaggagaugg ccgaggccua ccugggcaug cccguggcca acgccgugau cagcgugccc      540

gccgaguucg accugaagca gagaaacagc accaucgagg ccgccaaccu ggccggccug      600

aagauccuga gagugaucaa cgagcccacc gccgccgcca uggccuacgg ccugcacaag      660

gccgacgugu uccacgugcu ggugaucgac cugggcggcg gcacccugga cgugagccug      720

cugaacaagc agggcggcau guuccugacc agagccauga gcggcaacaa caagcugggc      780

ggccaggacu ucaaccagag acugcugcag uaccuguaca agcagaucua ccagaccuac      840

ggcuucgugc ccagcagaaa ggaggagauc cacagacuga gacaggccgu ggagauggug      900

aagcugaacc ugacccugca ccagagcgcc cagcugagcg ugcugcugac cguggaggag      960

caggacagaa aggagcccca cagcagcgac accgagcugc ccaaggacaa gcugagcagc     1020

gccgacgacc acagagugaa cagcggcuuc ggcagaggcc ugagcgacaa gaagagcggc     1080

gagagccagg ugcuguucga gaccgagauc agcagaaagc uguucgacac ccugaacgag     1140

gaccuguucc agaagauccu ggugcccauc cagcaggugc ugaaggaggg ccaccuggag     1200

aagaccgaga ucgacgaggu ggugcuggug ggcggcagca ccagaauccc cagaaucaga     1260

caggugaucc aggaguucuu cggcaaggac cccaacacca gcguggaccc cgaccuggcc     1320

guggugaccg gcguggccau ccaggccggc aucgacggcg gcagcuggcc ccugcaggug     1380

agcgcccugg agauccccaa caagcaccug cagaagacca acuucaacug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  1816
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt4)

<400>  1816
gggagaaagc uuaccauggc cgccaucggc gugcaccugg gcugcaccag cgccugcgug       60

gccguguaca aggacggcag agccggcgug guggccaacg acgccggcga cagagugacc      120

cccgccgugg uggccuacag cgagaacgag gagaucgugg gccuggccgc caagcagagc      180

agaaucagaa acaucagcaa caccgugaug aaggugaagc agauccuggg cagaagcagc      240

agcgaccccc aggcccagaa guacaucgcc gagagcaagu gccuggugau cgagaagaac      300

ggcaagcuga gauacgagau cgacaccggc gaggagacca aguucgugaa ccccgaggac      360

guggccagac ugaucuucag caagaugaag gagaccgccc acagcgugcu gggcagcgac      420

gccaacgacg uggugaucac cgugcccuuc gacuucggcg agaagcagaa gaacgcccug      480

ggcgaggccg ccagagccgc cggcuucaac gugcugagac ugauccacga gcccagcgcc      540

gcccugcugg ccuacggcau cggccaggac agccccaccg gcaagagcaa cauccuggug      600

uucaagcugg gcggcaccag ccugagccug agcgugaugg aggugaacag cggcaucuac      660

agagugcuga gcaccaacac cgacgacaac aucggcggcg cccacuucac cgagacccug      720

gcccaguacc uggccagcga guuccagaga agcuucaagc acgacgugag aggcaacgcc      780

agagccauga ugaagcugac caacagcgcc gagguggcca agcacagccu gagcacccug      840

ggcagcgcca acugcuuccu ggacagccug uacgagggcc aggacuucga cugcaacgug      900

agcagagcca gauucgagcu gcugugcagc ccccuguuca acaagugcau cgaggccauc      960

agaggccugc uggaccagaa cggcuucacc gccgacgaca ucaacaaggu ggugcugugc     1020

ggcggcagca gcagaauccc caagcugcag cagcugauca aggaccuguu ccccgccgug     1080

gagcugcuga acagcauccc ccccgacgag gugaucccca ucggcgccgc caucgaggcc     1140

ggcauccuga ucggcaagga gaaccugcug guggaggaca gccugaugau cgagugcagc     1200

gccagagaca uccuggugaa gggcguggac gagagcggcg ccagcagauu caccgugcug     1260

uuccccagcg gcaccccccu gcccgccaga agacagcaca cccugcaggc ccccggcagc     1320

aucagcagcg ugugccugga gcuguacgag agcgacggca agaacagcgc caaggaggag     1380

accaaguucg cccagguggu gcugcaggac cuggacaaga aggagaacgg ccugagagac     1440

auccuggccg ugcugaccau gaagagagac ggcagccugc acgugaccug caccgaccag     1500

gagaccggca agugcgaggc caucagcauc gagaucgcca gcugaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  1817
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt4)

<400>  1817
gggagaaagc uuaccaugag cguggugggc cuggacgugg gcagccagag cugcuacauc       60

gccguggcca gagccggcgg caucgagacc aucgccaacg aguucagcga cagaugcacc      120

cccagcguga ucagcuucgg cagcaagaac agaaccaucg gcguggccgc caagaaccag      180

cagaucaccc acgccaacaa caccgugagc aacuucaaga gauuccacgg cagagccuuc      240

aacgaccccu ucauccagaa ggagaaggag aaccugagcu acgaccuggu gccccugaag      300

aacggcggcg ugggcaucaa ggugauguac augggcgagg agcaccuguu cagcguggag      360

cagaucaccg ccaugcugcu gaccaagcug aaggagaccg ccgagaacag ccugaagaag      420

cccgugaccg acugcgugau cagcgugccc agcuucuuca ccgacgccga gagaagaagc      480

gugcuggacg ccgcccagau cgugggccug aacugccuga gacugaugaa cgacaugacc      540

gccguggccc ugaacuacgg caucuacaag caggaccugc ccagccugga cgagaagccc      600

agaaucgugg uguucgugga caugggccac agcgccuucc aggugagcgc cugcgccuuc      660

aacaagggca agcugaaggu gcugggcacc gccuucgacc ccuuccuggg cggcaagaac      720

uucgacgaga agcuggugga gcacuucugc gccgaguuca agaccaagua caagcuggac      780

gccaagagca agaucagagc ccugcugaga cuguaccagg agugcgagaa gcugaagaag      840

cugaugagca gcaacagcac cgaccugccc cugaacaucg agugcuucau gaacgacaag      900

gacgugagcg gcaagaugaa cagaagccag uucgaggagc ugugcgccga gcugcugcag      960

aagaucgagg ugccccugua cagccugcug gagcagaccc accugaaggu ggaggacgug     1020

agcgccgugg agaucguggg cggcgccacc agaauccccg ccgugaagga gagaaucgcc     1080

aaguucuucg gcaaggacau cagcaccacc cugaacgccg acgaggccgu ggccagaggc     1140

ugcgcccugc agugcgccau ccugagcccc gccuucaagg ugagagaguu cagcgugacc     1200

gacgccgugc ccuuccccau cagccugauc uggaaccacg acagcgagga caccgagggc     1260

gugcacgagg uguucagcag aaaccacgcc gcccccuuca gcaaggugcu gaccuuccug     1320

agaagaggcc ccuucgagcu ggaggccuuc uacagcgacc cccagggcgu gcccuacccc     1380

gaggccaaga ucggcagauu cguggugcag aacgugagcg cccagaagga cggcgagaag     1440

agcagaguga aggugaaggu gagagugaac acccacggca ucuucaccau cagcaccgcc     1500

agcauggugg agaaggugcc caccgaggag aacgagauga gcagcgaggc cgacauggag     1560

ugccugaacc agagaccccc cgagaacccc gacaccgaca agaacgugca gcaggacaac     1620

agcgaggccg gcacccagcc ccaggugcag accgacgccc agcagaccag ccagagcccc     1680

cccagccccg agcugaccag cgaggagaac aagauccccg acgccgacaa ggccaacgag     1740

aagaaggugg accagccccc cgaggccaag aagcccaaga ucaagguggu gaacguggag     1800

cugcccaucg aggccaaccu gguguggcag cugggcaagg accugcugaa cauguacauc     1860

gagaccgagg gcaagaugau caugcaggac aagcuggaga aggagagaaa cgacgccaag     1920

aacgccgugg aggaguacgu guacgaguuc agagacaagc ugugcggccc cuacgagaag     1980

uucaucugcg agcaggacca ccagaacuuc cugagacugc ugaccgagac cgaggacugg     2040

cuguacgagg agggcgagga ccaggccaag caggccuacg uggacaagcu ggaggagcug     2100

augaagaucg gcacccccgu gaaggugaga uuccaggagg ccgaggagag acccaagaug     2160

uucgaggagc ugggccagag acugcagcac uacgccaaga ucgccgccga cuucagaaac     2220

aaggacgaga aguacaacca caucgacgag agcgagauga agaaggugga gaagagcgug     2280

aacgagguga uggaguggau gaacaacgug augaacgccc aggccaagaa gagccuggac     2340

caggaccccg uggugagagc ccaggagauc aagaccaaga ucaaggagcu gaacaacacc     2400

ugcgagcccg uggugaccca gcccaagccc aagaucgaga gccccaagcu ggagagaacc     2460

cccaacggcc ccaacaucga caagaaggag gaggaccugg aggacaagaa caacuucggc     2520

gccgagcccc cccaccagaa cggcgagugc uaccccaacg agaagaacag cgugaacaug     2580

gaccuggacu gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  1818
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt4)

<400>  1818
gggagaaagc uuaccauggc cgacaaggug agaagacaga gacccagaag aagagugugc       60

ugggcccugg uggccgugcu gcuggccgac cugcuggccc ugagcgacac ccuggccgug      120

augagcgugg accugggcag cgagagcaug aagguggcca ucgugaagcc cggcgugccc      180

auggagaucg ugcugaacaa ggagagcaga agaaagaccc ccgugaucgu gacccugaag      240

gagaacgaga gauucuucgg cgacagcgcc gccagcaugg ccaucaagaa ccccaaggcc      300

acccugagau acuuccagca ccugcugggc aagcaggccg acaaccccca cguggcccug      360

uaccaggcca gauuccccga gcacgagcug accuucgacc cccagagaca gaccgugcac      420

uuccagauca gcagccagcu gcaguucagc cccgaggagg ugcugggcau ggugcugaac      480

uacagcagaa gccuggccga ggacuucgcc gagcagccca ucaaggacgc cgugaucacc      540

gugcccgugu ucuucaacca ggccgagaga agagccgugc ugcaggccgc cagaauggcc      600

ggccugaagg ugcugcagcu gaucaacgac aacaccgcca ccgcccugag cuacggcgug      660

uucagaagaa aggacaucaa caccaccgcc cagaacauca uguucuacga caugggcagc      720

ggcagcaccg ugugcaccau cgugaccuac cagaugguga agaccaagga ggccggcaug      780

cagccccagc ugcagaucag aggcgugggc uucgacagaa cccugggcgg ccuggagaug      840

gagcugagac ugagagagag acuggccggc cuguucaacg agcagagaaa gggccagaga      900

gccaaggacg ugagagagaa ccccagagcc auggccaagc ugcugagaga ggccaacaga      960

cugaagaccg ugcugagcgc caacgccgac cacauggccc agaucgaggg ccugauggac     1020

gacguggacu ucaaggccaa ggugaccaga guggaguucg aggagcugug cgccgaccug     1080

uucgagagag ugcccggccc cgugcagcag gcccugcaga gcgccgagau gagccuggac     1140

gagaucgagc aggugauccu ggugggcggc gccaccagag ugcccagagu gcaggaggug     1200

cugcugaagg ccgugggcaa ggaggagcug ggcaagaaca ucaacgccga cgaggccgcc     1260

gccaugggcg ccguguacca ggccgccgcc cugagcaagg ccuucaaggu gaagcccuuc     1320

guggugagag acgccguggu guaccccauc cugguggagu ucaccagaga gguggaggag     1380

gagcccggca uccacagccu gaagcacaac aagagagugc uguucagcag aaugggcccc     1440

uacccccaga gaaaggugau caccuucaac agauacagcc acgacuucaa cuuccacauc     1500

aacuacggcg accugggcuu ccugggcccc gaggaccuga gaguguucgg cagccagaac     1560

cugaccaccg ugaagcugaa gggcgugggc gacagcuuca agaaguaccc cgacuacgag     1620

agcaagggca ucaaggccca cuucaaccug gacgagagcg gcgugcugag ccuggacaga     1680

guggagagcg uguucgagac ccugguggag gacagcgccg aggaggagag cacccugacc     1740

aagcugggca acaccaucag cagccuguuc ggcggcggca ccacccccga cgccaaggag     1800

aacggcaccg acaccgugca ggaggaggag gagagccccg ccgagggcag caaggacgag     1860

cccggcgagc agguggagcu gaaggaggag gccgaggccc ccguggagga cggcagccag     1920

cccccccccc ccgagcccaa gggcgacgcc acccccgagg gcgagaaggc caccgagaag     1980

gagaacggcg acaagagcga ggcccagaag cccagcgaga aggccgaggc cggccccgag     2040

ggcguggccc ccgcccccga gggcgagaag aagcagaagc ccgccagaaa gagaagaaug     2100

guggaggaga ucggcgugga gcugguggug cuggaccugc ccgaccugcc cgaggacaag     2160

cuggcccaga gcgugcagaa gcugcaggac cugacccuga gagaccugga gaagcaggag     2220

agagagaagg ccgccaacag ccuggaggcc uucaucuucg agacccagga caagcuguac     2280

cagcccgagu accaggaggu gagcaccgag gagcagagag aggagaucag cggcaagcug     2340

agcgccgcca gcaccuggcu ggaggacgag ggcgugggcg ccaccaccgu gaugcugaag     2400

gagaagcugg ccgagcugag aaagcugugc cagggccugu ucuucagagu ggaggagaga     2460

aagaaguggc ccgagagacu gagcgcccug gacaaccugc ugaaccacag cagcauguuc     2520

cugaagggcg ccagacugau ccccgagaug gaccagaucu ucaccgaggu ggagaugacc     2580

acccuggaga aggugaucaa cgagaccugg gccuggaaga acgccacccu ggccgagcag     2640

gccaagcugc ccgccaccga gaagcccgug cugcugagca aggacaucga ggccaagaug     2700

auggcccugg acagagaggu gcaguaccug cugaacaagg ccaaguucac caagcccaga     2760

cccagaccca aggacaagaa cggcaccaga gccgagcccc cccugaacgc cagcgccagc     2820

gaccagggcg agaaggugau cccccccgcc ggccagaccg aggacgccga gcccaucagc     2880

gagcccgaga agguggagac cggcagcgag cccggcgaca ccgagccccu ggagcugggc     2940

ggccccggcg ccgagcccga gcagaaggag cagagcaccg gccagaagag accccugaag     3000

aacgacgagc ugugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1819
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt4)

<400>  1819
gggagaaagc uuaccaugcc cgaggagacc cagacccagg accagcccau ggaggaggag       60

gagguggaga ccuucgccuu ccaggccgag aucgcccagc ugaugagccu gaucaucaac      120

accuucuaca gcaacaagga gaucuuccug agagagcuga ucagcaacag cagcgacgcc      180

cuggacaaga ucagauacga gagccugacc gaccccagca agcuggacag cggcaaggag      240

cugcacauca accugauccc caacaagcag gacagaaccc ugaccaucgu ggacaccggc      300

aucggcauga ccaaggccga ccugaucaac aaccugggca ccaucgccaa gagcggcacc      360

aaggccuuca uggaggcccu gcaggccggc gccgacauca gcaugaucgg ccaguucggc      420

gugggcuucu acagcgccua ccugguggcc gagaagguga ccgugaucac caagcacaac      480

gacgacgagc aguacgccug ggagagcagc gccggcggca gcuucaccgu gagaaccgac      540

accggcgagc ccaugggcag aggcaccaag gugauccugc accugaagga ggaccagacc      600

gaguaccugg aggagagaag aaucaaggag aucgugaaga agcacagcca guucaucggc      660

uaccccauca cccuguucgu ggagaaggag agagacaagg aggugagcga cgacgaggcc      720

gaggagaagg aggacaagga ggaggagaag gagaaggagg agaaggagag cgaggacaag      780

cccgagaucg aggacguggg cagcgacgag gaggaggaga agaaggacgg cgacaagaag      840

aagaagaaga agaucaagga gaaguacauc gaccaggagg agcugaacaa gaccaagccc      900

aucuggacca gaaaccccga cgacaucacc aacgaggagu acggcgaguu cuacaagagc      960

cugaccaacg acugggagga ccaccuggcc gugaagcacu ucagcgugga gggccagcug     1020

gaguucagag cccugcuguu cgugcccaga agagcccccu ucgaccuguu cgagaacaga     1080

aagaagaaga acaacaucaa gcuguacgug agaagagugu ucaucaugga caacugcgag     1140

gagcugaucc ccgaguaccu gaacuucauc agaggcgugg uggacagcga ggaccugccc     1200

cugaacauca gcagagagau gcugcagcag agcaagaucc ugaaggugau cagaaagaac     1260

cuggugaaga agugccugga gcuguucacc gagcuggccg aggacaagga gaacuacaag     1320

aaguucuacg agcaguucag caagaacauc aagcugggca uccacgagga cagccagaac     1380

agaaagaagc ugagcgagcu gcugagauac uacaccagcg ccagcggcga cgagauggug     1440

agccugaagg acuacugcac cagaaugaag gagaaccaga agcacaucua cuacaucacc     1500

ggcgagacca aggaccaggu ggccaacagc gccuucgugg agagacugag aaagcacggc     1560

cuggagguga ucuacaugau cgagcccauc gacgaguacu gcgugcagca gcugaaggag     1620

uucgagggca agacccuggu gagcgugacc aaggagggcc uggagcugcc cgaggacgag     1680

gaggagaaga agaagcagga ggagaagaag accaaguucg agaaccugug caagaucaug     1740

aaggacaucc uggagaagaa gguggagaag guggugguga gcaacagacu ggugaccagc     1800

cccugcugca ucgugaccag caccuacggc uggaccgcca acauggagag aaucaugaag     1860

gcccaggccc ugagagacaa cagcaccaug ggcuacaugg ccgccaagaa gcaccuggag     1920

aucaaccccg accacagcau caucgagacc cugagacaga aggccgaggc cgacaagaac     1980

gacaagagcg ugaaggaccu ggugauccug cuguacgaga ccgcccugcu gagcagcggc     2040

uucagccugg aggaccccca gacccacgcc aacagaaucu acagaaugau caagcugggc     2100

cugggcaucg acgaggacga ccccaccgcc gacgacacca gcgccgccgu gaccgaggag     2160

augccccccc uggagggcga cgacgacacc agcagaaugg aggaggugga cugaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  1820
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt4)

<400>  1820
gggagaaagc uuaccaugga cagcagcaag cuggacagcg gcaagggccu gcacaucaac       60

cuggugccca acaagcagaa ccagacccug accaucgugg acaccagaau cggcaugacc      120

aagaccgacc ugaucaacaa ccugggcacc gugaccaaga gcggcaccaa ggccuucaug      180

gaggcccugc aggccgacgc cgacaucagc augaucggcc acuucggcgu gggcuucuac      240

agcgccuacc ugguggccaa gaaggugacc gugaucagca agcacaacaa cgacgagcag      300

uacaccuggg agagcagcgc cggcggcagc uucaccguga gaaccgacga gugaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  1821
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt4)

<400>  1821
gggagaaagc uuaccaugcc cgaggaggug caccacggcg aggaggaggu ggagaccuuc       60

gccuuccagg ccgagaucgc ccagcugaug agccugauca ucaacaccuu cuacagcaac      120

aaggagaucu uccugagaga gcugaucagc aacgccagcg acgcccugga caagaucaga      180

uacgagagcc ugaccgaccc cagcaagcug gacagcggca aggagcugaa gaucgacauc      240

auccccaacc cccaggagag aacccugacc cugguggaca ccggcaucgg caugaccaag      300

gccgaccuga ucaacaaccu gggcaccauc gccaagagcg gcaccaaggc cuucauggag      360

gcccugcagg ccggcgccga caucagcaug aucggccagu ucggcguggg cuucuacagc      420

gccuaccugg uggccgagaa ggugguggug aucaccaagc acaacgacga cgagcaguac      480

gccugggaga gcagcgccgg cggcagcuuc accgugagag ccgaccacgg cgagcccauc      540

ggcagaggca ccaaggugau ccugcaccug aaggaggacc agaccgagua ccuggaggag      600

agaagaguga aggagguggu gaagaagcac agccaguuca ucggcuaccc caucacccug      660

uaccuggaga aggagagaga gaaggagauc agcgacgacg aggccgagga ggagaagggc      720

gagaaggagg aggaggacaa ggacgacgag gagaagccca agaucgagga cgugggcagc      780

gacgaggagg acgacagcgg caaggacaag aagaagaaga ccaagaagau caaggagaag      840

uacaucgacc aggaggagcu gaacaagacc aagcccaucu ggaccagaaa ccccgacgac      900

aucacccagg aggaguacgg cgaguucuac aagagccuga ccaacgacug ggaggaccac      960

cuggccguga agcacuucag cguggagggc cagcuggagu ucagagcccu gcuguucauc     1020

cccagaagag cccccuucga ccuguucgag aacaagaaga agaagaacaa caucaagcug     1080

uacgugagaa gaguguucau cauggacagc ugcgacgagc ugauccccga guaccugaac     1140

uucaucagag gcguggugga cagcgaggac cugccccuga acaucagcag agagaugcug     1200

cagcagagca agauccugaa ggugaucaga aagaacaucg ugaagaagug ccuggagcug     1260

uucagcgagc uggccgagga caaggagaac uacaagaagu ucuacgaggc cuucagcaag     1320

aaccugaagc ugggcaucca cgaggacagc accaacagaa gaagacugag cgagcugcug     1380

agauaccaca ccagccagag cggcgacgag augaccagcc ugagcgagua cgugagcaga     1440

augaaggaga cccagaagag caucuacuac aucaccggcg agagcaagga gcagguggcc     1500

aacagcgccu ucguggagag agugagaaag agaggcuucg agguggugua caugaccgag     1560

cccaucgacg aguacugcgu gcagcagcug aaggaguucg acggcaagag ccuggugagc     1620

gugaccaagg agggccugga gcugcccgag gacgaggagg agaagaagaa gauggaggag     1680

agcaaggcca aguucgagaa ccugugcaag cugaugaagg agauccugga caagaaggug     1740

gagaagguga ccaucagcaa cagacuggug agcagccccu gcugcaucgu gaccagcacc     1800

uacggcugga ccgccaacau ggagagaauc augaaggccc aggcccugag agacaacagc     1860

accaugggcu acaugauggc caagaagcac cuggagauca accccgacca ccccaucgug     1920

gagacccuga gacagaaggc cgaggccgac aagaacgaca aggccgugaa ggaccuggug     1980

gugcugcugu ucgagaccgc ccugcugagc agcggcuuca gccuggagga cccccagacc     2040

cacagcaaca gaaucuacag aaugaucaag cugggccugg gcaucgacga ggacgaggug     2100

gccgccgagg agcccaacgc cgccgugccc gacgagaucc ccccccugga gggcgacgag     2160

gacgccagca gaauggagga gguggacuga ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  1822
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt4)

<400>  1822
gggagaaagc uuaccaugag agcccugugg gugcugggcc ugugcugcgu gcugcugacc       60

uucggcagcg ugagagccga cgacgaggug gacguggacg gcaccgugga ggaggaccug      120

ggcaagagca gagagggcag cagaaccgac gacgaggugg ugcagagaga ggaggaggcc      180

auccagcugg acggccugaa cgccagccag aucagagagc ugagagagaa gagcgagaag      240

uucgccuucc aggccgaggu gaacagaaug augaagcuga ucaucaacag ccuguacaag      300

aacaaggaga ucuuccugag agagcugauc agcaacgcca gcgacgcccu ggacaagauc      360

agacugauca gccugaccga cgagaacgcc cugagcggca acgaggagcu gaccgugaag      420

aucaagugcg acaaggagaa gaaccugcug cacgugaccg acaccggcgu gggcaugacc      480

agagaggagc uggugaagaa ccugggcacc aucgccaaga gcggcaccag cgaguuccug      540

aacaagauga ccgaggccca ggaggacggc cagagcacca gcgagcugau cggccaguuc      600

ggcgugggcu ucuacagcgc cuuccuggug gccgacaagg ugaucgugac cagcaagcac      660

aacaacgaca cccagcacau cugggagagc gacagcaacg aguucagcgu gaucgccgac      720

cccagaggca acacccuggg cagaggcacc accaucaccc uggugcugaa ggaggaggcc      780

agcgacuacc uggagcugga caccaucaag aaccugguga agaaguacag ccaguucauc      840

aacuucccca ucuacgugug gagcagcaag accgagaccg uggaggagcc cauggaggag      900

gaggaggccg ccaaggagga gaaggaggag agcgacgacg aggccgccgu ggaggaggag      960

gaggaggaga agaagcccaa gaccaagaag guggagaaga ccguguggga cugggagcug     1020

augaacgaca ucaagcccau cuggcagaga cccagcaagg agguggagga ggacgaguac     1080

aaggccuucu acaagagcuu cagcaaggag agcgacgacc ccauggccua cauccacuuc     1140

accgccgagg gcgaggugac cuucaagagc auccuguucg ugcccaccag cgcccccaga     1200

ggccuguucg acgaguacgg cagcaagaag agcgacuaca ucaagcugua cgugagaaga     1260

guguucauca ccgacgacuu ccacgacaug augcccaagu accugaacuu cgugaagggc     1320

gugguggaca gcgacgaccu gccccugaac gugagcagag agacccugca gcagcacaag     1380

cugcugaagg ugaucagaaa gaagcuggug agaaagaccc uggacaugau caagaagauc     1440

gccgacgaca aguacaacga caccuucugg aaggaguucg gcaccaacau caagcugggc     1500

gugaucgagg accacagcaa cagaaccaga cuggccaagc ugcugagauu ccagagcagc     1560

caccacccca ccgacaucac cagccuggac caguacgugg agagaaugaa ggagaagcag     1620

gacaagaucu acuucauggc cggcagcagc agaaaggagg ccgagagcag ccccuucgug     1680

gagagacugc ugaagaaggg cuacgaggug aucuaccuga ccgagcccgu ggacgaguac     1740

ugcauccagg cccugcccga guucgacggc aagagauucc agaacguggc caaggagggc     1800

gugaaguucg acgagagcga gaagaccaag gagagcagag aggccgugga gaaggaguuc     1860

gagccccugc ugaacuggau gaaggacaag gcccugaagg acaagaucga gaaggccgug     1920

gugagccaga gacugaccga gagccccugc gcccuggugg ccagccagua cggcuggagc     1980

ggcaacaugg agagaaucau gaaggcccag gccuaccaga ccggcaagga caucagcacc     2040

aacuacuacg ccagccagaa gaagaccuuc gagaucaacc ccagacaccc ccugaucaga     2100

gacaugcuga gaagaaucaa ggaggacgag gacgacaaga ccgugcugga ccuggccgug     2160

gugcuguucg agaccgccac ccugagaagc ggcuaccugc ugcccgacac caaggccuac     2220

ggcgacagaa ucgagagaau gcugagacug agccugaaca ucgaccccga cgccaaggug     2280

gaggaggagc ccgaggagga gcccgaggag accgccgagg acaccaccga ggacaccgag     2340

caggacgagg acgaggagau ggacgugggc accgacgagg aggaggagac cgccaaggag     2400

agcaccgccg agaaggacga gcugugagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  1823
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt4)

<400>  1823
gggagaaagc uuaccauggc cagagagcug agagcccugc ugcugugggg cagaagacug       60

agaccccugc ugagagcccc cgcccuggcc gccgugcccg gcggcaagcc cauccugugc      120

cccagaagaa ccaccgccca gcugggcccc agaagaaacc ccgccuggag ccugcaggcc      180

ggcagacugu ucagcaccca gaccgccgag gacaaggagg agccccugca cagcaucauc      240

agcagcaccg agagcgugca gggcagcacc agcaagcacg aguuccaggc cgagaccaag      300

aagcugcugg acaucguggc cagaagccug uacagcgaga aggagguguu caucagagag      360

cugaucagca acgccagcga cgcccuggag aagcugagac acaagcuggu gagcgacggc      420

caggcccugc ccgagaugga gauccaccug cagaccaacg ccgagaaggg caccaucacc      480

auccaggaca ccggcaucgg caugacccag gaggagcugg ugagcaaccu gggcaccauc      540

gccagaagcg gcagcaaggc cuuccuggac gcccugcaga accaggccga ggccagcagc      600

aagaucaucg gccaguucgg cgugggcuuc uacagcgccu ucaugguggc cgacagagug      660

gagguguaca gcagaagcgc cgcccccggc agccugggcu accaguggcu gagcgacggc      720

agcggcgugu ucgagaucgc cgaggccagc ggcgugagaa ccggcaccaa gaucaucauc      780

caccugaaga gcgacugcaa ggaguucagc agcgaggcca gagugagaga cguggugacc      840

aaguacagca acuucgugag cuucccccug uaccugaacg gcagaagaau gaacacccug      900

caggccaucu ggaugaugga ccccaaggac gugagagagu ggcagcacga ggaguucuac      960

agauacgugg cccaggccca cgacaagccc agauacaccc ugcacuacaa gaccgacgcc     1020

ccccugaaca ucagaagcau cuucuacgug cccgacauga agcccagcau guucgacgug     1080

agcagagagc ugggcagcag cguggcccug uacagcagaa aggugcugau ccagaccaag     1140

gccaccgaca uccugcccaa guggcugaga uucaucagag gcguggugga cagcgaggac     1200

aucccccuga accugagcag agagcugcug caggagagcg cccugaucag aaagcugaga     1260

gacgugcugc agcagagacu gaucaaguuc uucaucgacc agagcaagaa ggacgccgag     1320

aaguacgcca aguucuucga ggacuacggc cuguucauga gagagggcau cgugaccgcc     1380

accgagcagg aggugaagga ggacaucgcc aagcugcuga gauacgagag cagcgcccug     1440

cccagcggcc agcugaccag ccugagcgag uacgccagca gaaugagagc cggcaccaga     1500

aacaucuacu accugugcgc ccccaacaga caccuggccg agcacagccc cuacuacgag     1560

gccaugaaga agaaggacac cgaggugcug uucugcuucg agcaguucga cgagcugacc     1620

cugcugcacc ugagagaguu cgacaagaag aagcugauca gcguggagac cgacaucgug     1680

guggaccacu acaaggagga gaaguucgag gacagaagcc ccgccgccga gugccugagc     1740

gagaaggaga ccgaggagcu gauggccugg augagaaacg ugcugggcag cagagugacc     1800

aacgugaagg ugacccugag acuggacacc caccccgcca uggugaccgu gcuggagaug     1860

ggcgccgcca gacacuuccu gagaaugcag cagcuggcca agacccagga ggagagagcc     1920

cagcugcugc agcccacccu ggagaucaac cccagacacg cccugaucaa gaagcugaac     1980

cagcugagag ccagcgagcc cggccuggcc cagcugcugg uggaccagau cuacgagaac     2040

gccaugaucg ccgccggccu gguggacgac cccagagcca uggugggcag acugaacgag     2100

cugcugguga aggcccugga gagacacuga ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  1824
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt4)

<400>  1824
gggagaaagc uuaccauggg caagaucagc agccugccca cccagcuguu caagugcugc       60

uucugcgacu uccugaaggu gaagaugcac accaugagca gcagccaccu guucuaccug      120

gcccugugcc ugcugaccuu caccagcagc gccaccgccg gccccgagac ccugugcggc      180

gccgagcugg uggacgcccu gcaguucgug ugcggcgaca gaggcuucua cuucaacaag      240

cccaccggcu acggcagcag cagcagaaga gccccccaga ccggcaucgu ggacgagugc      300

ugcuucagaa gcugcgaccu gagaagacug gagauguacu gcgccccccu gaagcccgcc      360

aagagcgcca gaagcgugag agcccagaga cacaccgaca ugcccaagac ccagaaggag      420

gugcaccuga agaacgccag cagaggcagc gccggcaaca agaacuacag aaugugagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  1825
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt4)

<400>  1825
gggagaaagc uuaccauggg cauccccaug ggcaagagca ugcuggugcu gcugaccuuc       60

cuggccuucg ccagcugcug caucgccgcc uacagaccca gcgagacccu gugcggcggc      120

gagcuggugg acacccugca guucgugugc ggcgacagag gcuucuacuu cagcagaccc      180

gccagcagag ugagcagaag aagcagaggc aucguggagg agugcugcuu cagaagcugc      240

gaccuggccc ugcuggagac cuacugcgcc acccccgcca agagcgagag agacgugagc      300

acccccccca ccgugcugcc cgacaacuuc cccagauacc ccgugggcaa guucuuccag      360

uacgacaccu ggaagcagag cacccagaga cugagaagag gccugcccgc ccugcugaga      420

gccagaagag gccacgugcu ggccaaggag cuggaggccu ucagagaggc caagagacac      480

agaccccuga ucgcccugcc cacccaggac cccgcccacg gcggcgcccc ccccgagaug      540

gccagcaaca gaaagugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  1826
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt4)

<400>  1826
gggagaaagc uuaccaugaa cagcuucagc accagcgccu ucggccccgu ggccuucagc       60

cugggccugc ugcuggugcu gcccgccgcc uuccccgccc ccgugccccc cggcgaggac      120

agcaaggacg uggccgcccc ccacagacag ccccugacca gcagcgagag aaucgacaag      180

cagaucagau acauccugga cggcaucagc gcccugagaa aggagaccug caacaagagc      240

aacaugugcg agagcagcaa ggaggcccug gccgagaaca accugaaccu gcccaagaug      300

gccgagaagg acggcugcuu ccagagcggc uucaacgagg agaccugccu ggugaagauc      360

aucaccggcc ugcuggaguu cgagguguac cuggaguacc ugcagaacag auucgagagc      420

agcgaggagc aggccagagc cgugcagaug agcaccaagg ugcugaucca guuccugcag      480

aagaaggcca agaaccugga cgccaucacc acccccgacc ccaccaccaa cgccagccug      540

cugaccaagc ugcaggccca gaaccagugg cugcaggaca ugaccaccca ccugauccug      600

agaagcuuca aggaguuccu gcagagcagc cugagagccc ugagacagau gugaggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  1827
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt4)

<400>  1827
gggagaaagc uuaccaugcc ccugcugugg cugagaggcu uccugcuggc cagcugcugg       60

aucaucguga gaagcagccc cacccccggc agcgagggcc acagcgccgc ccccgacugc      120

cccagcugcg cccuggccgc ccugcccaag gacgugccca acagccagcc cgagauggug      180

gaggccguga agaagcacau ccugaacaug cugcaccuga agaagagacc cgacgugacc      240

cagcccgugc ccaaggccgc ccugcugaac gccaucagaa agcugcacgu gggcaaggug      300

ggcgagaacg gcuacgugga gaucgaggac gacaucggca gaagagccga gaugaacgag      360

cugauggagc agaccagcga gaucaucacc uucgccgaga gcggcaccgc cagaaagacc      420

cugcacuucg agaucagcaa ggagggcagc gaccugagcg ugguggagag agccgaggug      480

uggcuguucc ugaaggugcc caaggccaac agaaccagaa ccaaggugac caucagacug      540

uuccagcagc agaagcaccc ccagggcagc cuggacaccg gcgaggaggc cgaggaggug      600

ggccugaagg gcgagagaag cgagcugcug cugagcgaga agguggugga cgccagaaag      660

agcaccuggc acguguuccc cgugagcagc agcauccaga gacugcugga ccagggcaag      720

agcagccugg acgugagaau cgccugcgag cagugccagg agagcggcgc cagccuggug      780

cugcugggca agaagaagaa gaaggaggag gagggcgagg gcaagaagaa gggcggcggc      840

gagggcggcg ccggcgccga cgaggagaag gagcagagcc acagacccuu ccugaugcug      900

caggccagac agagcgagga ccacccccac agaagaagaa gaagaggccu ggagugcgac      960

ggcaagguga acaucugcug caagaagcag uucuucguga gcuucaagga caucggcugg     1020

aacgacugga ucaucgcccc cagcggcuac cacgccaacu acugcgaggg cgagugcccc     1080

agccacaucg ccggcaccag cggcagcagc cugagcuucc acagcaccgu gaucaaccac     1140

uacagaauga gaggccacag ccccuucgcc aaccugaaga gcugcugcgu gcccaccaag     1200

cugagaccca ugagcaugcu guacuacgac gacggccaga acaucaucaa gaaggacauc     1260

cagaacauga ucguggagga gugcggcugc agcugaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  1828
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt4)

<400>  1828
gggagaaagc uuaccaugga cggccugccc ggcagagccc ugggcgccgc cugccugcug       60

cugcuggccg ccggcuggcu gggccccgag gccuggggca gccccacccc cccccccacc      120

cccgccgccc cccccccccc cccccccccc ggcagccccg gcggcagcca ggacaccugc      180

accagcugcg gcggcuucag aagacccgag gagcugggca gaguggacgg cgacuuccug      240

gaggccguga agagacacau ccugagcaga cugcagauga gaggcagacc caacaucacc      300

cacgccgugc ccaaggccgc cauggugacc gcccugagaa agcugcacgc cggcaaggug      360

agagaggacg gcagagugga gaucccccac cuggacggcc acgccagccc cggcgccgac      420

ggccaggaga gagugagcga gaucaucagc uucgccgaga ccgacggccu ggccagcagc      480

agagugagac uguacuucuu caucagcaac gagggcaacc agaaccuguu cguggugcag      540

gccagccugu ggcuguaccu gaagcugcug cccuacgugc uggagaaggg cagcagaaga      600

aaggugagag ugaaggugua cuuccaggag cagggccacg gcgacagaug gaacauggug      660

gagaagagag uggaccugaa gagaagcggc uggcacaccu ucccccugac cgaggccauc      720

caggcccugu ucgagagagg cgagagaaga cugaaccugg acgugcagug cgacagcugc      780

caggagcugg ccguggugcc cguguucgug gaccccggcg aggagagcca cagacccuuc      840

gugguggugc aggccagacu gggcgacagc agacacagaa ucagaaagag aggccuggag      900

ugcgacggca gaaccaaccu gugcugcaga cagcaguucu ucaucgacuu cagacugauc      960

ggcuggaacg acuggaucau cgcccccacc ggcuacuacg gcaacuacug cgagggcagc     1020

ugccccgccu accuggccgg cgugcccggc agcgccagca gcuuccacac cgccguggug     1080

aaccaguaca gaaugagagg ccugaacccc ggcaccguga acagcugcug cauccccacc     1140

aagcugagca ccaugagcau gcuguacuuc gacgacgagu acaacaucgu gaagagagac     1200

gugcccaaca ugaucgugga ggagugcggc ugcgccugag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  1829
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt4)

<400>  1829
gggagaaagc uuaccauggc ccugagagug cugcugcuga ccgcccugac ccugugccac       60

ggcuucaacc uggacaccga gaacgccaug accuuccagg agaacgccag aggcuucggc      120

cagagcgugg ugcagcugca gggcagcaga gugguggugg gcgcccccca ggagaucgug      180

gccgccaacc agagaggcag ccuguaccag ugcgacuaca gcaccggcag cugcgagccc      240

aucagacugc aggugcccgu ggaggccgug aacaugagcc ugggccugag ccuggccgcc      300

accaccagcc ccccccagcu gcuggccugc ggccccaccg ugcaccagac cugcagcgag      360

aacaccuacg ugaagggccu gugcuuccug uucggcagca accugagaca gcagccccag      420

aaguuccccg aggcccugag aggcugcccc caggaggaca gcgacaucgc cuuccugauc      480

gacggcagcg gcagcaucau cccccacgac uucagaagaa ugaaggaguu cgugagcacc      540

gugauggagc agcugaagaa gagcaagacc cuguucagcc ugaugcagua cagcgaggag      600

uucagaaucc acuucaccuu caaggaguuc cagaacaacc ccaaccccag aagccuggug      660

aagcccauca cccagcugcu gggcagaacc cacaccgcca ccggcaucag aaagguggug      720

agagagcugu ucaacaucac caacggcgcc agaaagaacg ccuucaagau ccugguggug      780

aucaccgacg gcgagaaguu cggcgacccc cugggcuacg aggacgugau ccccgaggcc      840

gacagagagg gcgugaucag auacgugauc ggcgugggcg acgccuucag aagcgagaag      900

agcagacagg agcugaacac caucgccagc aagcccccca gagaccacgu guuccaggug      960

aacaacuucg aggcccugaa gaccauccag aaccagcuga gagagaagau cuucgccauc     1020

gagggcaccc agaccggcag cagcagcagc uucgagcacg agaugagcca ggagggcuuc     1080

agcgccgcca ucaccagcaa cggcccccug cugagcaccg ugggcagcua cgacugggcc     1140

ggcggcgugu uccuguacac cagcaaggag aagagcaccu ucaucaacau gaccagagug     1200

gacagcgaca ugaacgacgc cuaccugggc uacgccgccg ccaucauccu gagaaacaga     1260

gugcagagcc uggugcuggg cgcccccaga uaccagcaca ucggccuggu ggccauguuc     1320

agacagaaca ccggcaugug ggagagcaac gccaacguga agggcaccca gaucggcgcc     1380

uacuucggcg ccagccugug cagcguggac guggacagca acggcagcac cgaccuggug     1440

cugaucggcg ccccccacua cuacgagcag accagaggcg gccaggugag cgugugcccc     1500

cugcccagag gcagagccag auggcagugc gacgccgugc uguacggcga gcagggccag     1560

cccuggggca gauucggcgc cgcccugacc gugcugggcg acgugaacgg cgacaagcug     1620

accgacgugg ccaucggcgc ccccggcgag gaggacaaca gaggcgccgu guaccuguuc     1680

cacggcacca gcggcagcgg caucagcccc agccacagcc agagaaucgc cggcagcaag     1740

cugagcccca gacugcagua cuucggccag agccugagcg gcggccagga ccugaccaug     1800

gacggccugg uggaccugac cgugggcgcc cagggccacg ugcugcugcu gagaagccag     1860

cccgugcuga gagugaaggc caucauggag uucaacccca gagagguggc cagaaacgug     1920

uucgagugca acgaccaggu ggugaagggc aaggaggccg gcgaggugag agugugccug     1980

cacgugcaga agagcaccag agacagacug agagagggcc agauccagag cguggugacc     2040

uacgaccugg cccuggacag cggcagaccc cacagcagag ccguguucaa cgagaccaag     2100

aacagcacca gaagacagac ccaggugcug ggccugaccc agaccugcga gacccugaag     2160

cugcagcugc ccaacugcau cgaggacccc gugagcccca ucgugcugag acugaacuuc     2220

agccuggugg gcaccccccu gagcgccuuc ggcaaccuga gacccgugcu ggccgaggac     2280

gcccagagac uguucaccgc ccuguucccc uucgagaaga acugcggcaa cgacaacauc     2340

ugccaggacg accugagcau caccuucagc uucaugagcc uggacugccu gguggugggc     2400

ggccccagag aguucaacgu gaccgugacc gugagaaacg acggcgagga cagcuacaga     2460

acccagguga ccuucuucuu cccccuggac cugagcuaca gaaaggugag cacccugcag     2520

aaccagagaa gccagagaag cuggagacug gccugcgaga gcgccagcag caccgaggug     2580

agcggcgccc ugaagagcac cagcugcagc aucaaccacc ccaucuuccc cgagaacagc     2640

gaggugaccu ucaacaucac cuucgacgug gacagcaagg ccagccuggg caacaagcug     2700

cugcugaagg ccaacgugac cagcgagaac aacaugccca gaaccaacaa gaccgaguuc     2760

cagcuggagc ugcccgugaa guacgccgug uacauggugg ugaccagcca cggcgugagc     2820

accaaguacc ugaacuucac cgccagcgag aacaccagca gagugaugca gcaccaguac     2880

caggugagca accugggcca gagaagccug cccaucagcc ugguguuccu ggugcccgug     2940

agacugaacc agaccgugau cugggacaga ccccagguga ccuucagcga gaaccugagc     3000

agcaccugcc acaccaagga gagacugccc agccacagcg acuuccuggc cgagcugaga     3060

aaggcccccg uggugaacug cagcaucgcc gugugccaga gaauccagug cgacaucccc     3120

uucuucggca uccaggagga guucaacgcc acccugaagg gcaaccugag cuucgacugg     3180

uacaucaaga ccagccacaa ccaccugcug aucgugagca ccgccgagau ccuguucaac     3240

gacagcgugu ucacccugcu gcccggccag ggcgccuucg ugagaagcca gaccgagacc     3300

aagguggagc ccuucgaggu gcccaacccc cugccccuga ucgugggcag cagcgugggc     3360

ggccugcugc ugcuggcccu gaucaccgcc gcccuguaca agcugggcuu cuucaagaga     3420

caguacaagg acaugaugag cgagggcggc ccccccggcg ccgagcccca gugaggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  1830
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt4)

<400>  1830
gggagaaagc uuaccauguu cagccugaag acccugcccu uccugcugcu gcugcacgug       60

cagaucagca aggccuuccc cgugagcagc aaggagaaga acaccaagac cgugcaggac      120

uaccuggaga aguucuacca gcugcccagc aaccaguacc agagcaccag aaagaacggc      180

accaacguga ucguggagaa gcugaaggag augcagagau ucuucggccu gaacgugacc      240

ggcaagccca acgaggagac ccuggacaug augaagaagc ccagaugcgg cgugcccgac      300

agcggcggcu ucaugcugac ccccggcaac cccaaguggg agagaaccaa ccugaccuac      360

agaaucagaa acuacacccc ccagcugagc gaggccgagg uggagagagc caucaaggac      420

gccuucgagc uguggagcgu ggccagcccc cugaucuuca ccagaaucag ccagggcgag      480

gccgacauca acaucgccuu cuaccagaga gaccacggcg acaacagccc cuucgacggc      540

cccaacggca uccuggccca cgccuuccag cccggccagg gcaucggcgg cgacgcccac      600

uucgacgccg aggagaccug gaccaacacc agcgccaacu acaaccuguu ccugguggcc      660

gcccacgagu ucggccacag ccugggccug gcccacagca gcgaccccgg cgcccugaug      720

uaccccaacu acgccuucag agagaccagc aacuacagcc ugccccagga cgacaucgac      780

ggcauccagg ccaucuacgg ccugagcagc aaccccaucc agcccaccgg ccccagcacc      840

cccaagcccu gcgaccccag ccugaccuuc gacgccauca ccacccugag aggcgagauc      900

cuguucuuca aggacagaua cuucuggaga agacaccccc agcugcagag aguggagaug      960

aacuucauca gccuguucug gcccagccug cccaccggca uccaggccgc cuacgaggac     1020

uucgacagag accugaucuu ccuguucaag ggcaaccagu acugggcccu gagcggcuac     1080

gacauccugc agggcuaccc caaggacauc agcaacuacg gcuuccccag cagcgugcag     1140

gccaucgacg ccgccguguu cuacagaagc aagaccuacu ucuucgugaa cgaccaguuc     1200

uggagauacg acaaccagag acaguucaug gagcccggcu accccaagag caucagcggc     1260

gccuuccccg gcaucgagag caagguggac gccguguucc agcaggagca cuucuuccac     1320

guguucagcg gccccagaua cuacgccuuc gaccugaucg cccagagagu gaccagagug     1380

gccagaggca acaaguggcu gaacugcaga uacggcugag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  1831
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt4)

<400>  1831
gggagaaagc uuaccaugag ccuguggcag ccccuggugc uggugcugcu ggugcugggc       60

ugcugcuucg ccgcccccag acagagacag agcacccugg ugcuguuccc cggcgaccug      120

agaaccaacc ugaccgacag acagcuggcc gaggaguacc uguacagaua cggcuacacc      180

agaguggccg agaugagagg cgagagcaag agccugggcc ccgcccugcu gcugcugcag      240

aagcagcuga gccugcccga gaccggcgag cuggacagcg ccacccugaa ggccaugaga      300

acccccagau gcggcgugcc cgaccugggc agauuccaga ccuucgaggg cgaccugaag      360

uggcaccacc acaacaucac cuacuggauc cagaacuaca gcgaggaccu gcccagagcc      420

gugaucgacg acgccuucgc cagagccuuc gcccugugga gcgccgugac cccccugacc      480

uucaccagag uguacagcag agacgccgac aucgugaucc aguucggcgu ggccgagcac      540

ggcgacggcu accccuucga cggcaaggac ggccugcugg cccacgccuu cccccccggc      600

cccggcaucc agggcgacgc ccacuucgac gacgacgagc uguggagccu gggcaagggc      660

gugguggugc ccaccagauu cggcaacgcc gacggcgccg ccugccacuu ccccuucauc      720

uucgagggca gaagcuacag cgccugcacc accgacggca gaagcgacgg ccugcccugg      780

ugcagcacca ccgccaacua cgacaccgac gacagauucg gcuucugccc cagcgagaga      840

cuguacaccc aggacggcaa cgccgacggc aagcccugcc aguuccccuu caucuuccag      900

ggccagagcu acagcgccug caccaccgac ggcagaagcg acggcuacag auggugcgcc      960

accaccgcca acuacgacag agacaagcug uucggcuucu gccccaccag agccgacagc     1020

accgugaugg gcggcaacag cgccggcgag cugugcgugu uccccuucac cuuccugggc     1080

aaggaguaca gcaccugcac cagcgagggc agaggcgacg gcagacugug gugcgccacc     1140

accagcaacu ucgacagcga caagaagugg ggcuucugcc ccgaccaggg cuacagccug     1200

uuccuggugg ccgcccacga guucggccac gcccugggcc uggaccacag cagcgugccc     1260

gaggcccuga uguaccccau guacagauuc accgagggcc ccccccugca caaggacgac     1320

gugaacggca ucagacaccu guacggcccc agacccgagc ccgagcccag accccccacc     1380

accaccaccc cccagcccac cgcccccccc accgugugcc ccaccggccc ccccaccgug     1440

caccccagcg agagacccac cgccggcccc accggccccc ccagcgccgg ccccaccggc     1500

ccccccaccg ccggccccag caccgccacc accgugcccc ugagccccgu ggacgacgcc     1560

ugcaacguga acaucuucga cgccaucgcc gagaucggca accagcugua ccuguucaag     1620

gacggcaagu acuggagauu cagcgagggc agaggcagca gaccccaggg ccccuuccug     1680

aucgccgaca aguggcccgc ccugcccaga aagcuggaca gcguguucga ggagagacug     1740

agcaagaagc uguucuucuu cagcggcaga cagguguggg uguacaccgg cgccagcgug     1800

cugggcccca gaagacugga caagcugggc cugggcgccg acguggccca ggugaccggc     1860

gcccugagaa gcggcagagg caagaugcug cuguucagcg gcagaagacu guggagauuc     1920

gacgugaagg cccagauggu ggaccccaga agcgccagcg agguggacag aauguucccc     1980

ggcgugcccc uggacaccca cgacguguuc caguacagag agaaggccua cuucugccag     2040

gacagauucu acuggagagu gagcagcaga agcgagcuga accaggugga ccaggugggc     2100

uacgugaccu acgacauccu gcagugcccc gaggacugag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  1832
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt4)

<400>  1832
gggagaaagc uuaccaugca ccccggcgug cuggccgccu uccuguuccu gagcuggacc       60

cacugcagag cccugccccu gcccagcggc ggcgacgagg acgaccugag cgaggaggac      120

cugcaguucg ccgagagaua ccugagaagc uacuaccacc ccaccaaccu ggccggcauc      180

cugaaggaga acgccgccag cagcaugacc gagagacuga gagagaugca gagcuucuuc      240

ggccuggagg ugaccggcaa gcuggacgac aacacccugg acgugaugaa gaagcccaga      300

ugcggcgugc ccgacguggg cgaguacaac guguucccca gaacccugaa guggagcaag      360

augaaccuga ccuacagaau cgugaacuac acccccgaca ugacccacag cgagguggag      420

aaggccuuca agaaggccuu caaggugugg agcgacguga ccccccugaa cuucaccaga      480

cugcacgacg gcaucgccga caucaugauc agcuucggca ucaaggagca cggcgacuuc      540

uaccccuucg acggccccag cggccugcug gcccacgccu ucccccccgg ccccaacuac      600

ggcggcgacg cccacuucga cgacgacgag accuggacca gcagcagcaa gggcuacaac      660

cuguuccugg uggccgccca cgaguucggc cacagccugg gccuggacca cagcaaggac      720

cccggcgccc ugauguuccc caucuacacc uacaccggca agagccacuu caugcugccc      780

gacgacgacg ugcagggcau ccagagccug uacggccccg gcgacgagga ccccaacccc      840

aagcacccca agacccccga caagugcgac cccagccuga gccuggacgc caucaccagc      900

cugagaggcg agaccaugau cuucaaggac agauucuucu ggagacugca cccccagcag      960

guggacgccg agcuguuccu gaccaagagc uucuggcccg agcugcccaa cagaaucgac     1020

gccgccuacg agcaccccag ccacgaccug aucuucaucu ucagaggcag aaaguucugg     1080

gcccugaacg gcuacgacau ccuggagggc uaccccaaga agaucagcga gcugggccug     1140

cccaaggagg ugaagaagau cagcgccgcc gugcacuucg aggacaccgg caagacccug     1200

cuguucagcg gcaaccaggu guggagauac gacgacacca accacaucau ggacaaggac     1260

uaccccagac ugaucgagga ggacuucccc ggcaucggcg acaaggugga cgccguguac     1320

gagaagaacg gcuacaucua cuucuucaac ggccccaucc aguucgagua cagcaucugg     1380

agcaacagaa ucgugagagu gaugcccgcc aacagcaucc uguggugcug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  1833
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt4)

<400>  1833
gggagaaagc uuaccaugga gacccccaac accaccgagg acuacgacac caccaccgag       60

uucgacuacg gcgacgccac ccccugccag aaggugaacg agagagccuu cggcgcccag      120

cugcugcccc cccuguacag ccugguguuc gugaucggcc uggugggcaa cauccuggug      180

gugcuggugc uggugcagua caagagacug aagaacauga ccagcaucua ccugcugaac      240

cuggccauca gcgaccugcu guuccuguuc acccugcccu ucuggaucga cuacaagcug      300

aaggacgacu ggguguucgg cgacgccaug ugcaagaucc ugagcggcuu cuacuacacc      360

ggccuguaca gcgagaucuu cuucaucauc cugcugacca ucgacagaua ccuggccauc      420

gugcacgccg uguucgcccu gagagccaga accgugaccu ucggcgugau caccagcauc      480

aucaucuggg cccuggccau ccuggccagc augcccggcc uguacuucag caagacccag      540

ugggaguuca cccaccacac cugcagccug cacuuccccc acgagagccu gagagagugg      600

aagcuguucc aggcccugaa gcugaaccug uucggccugg ugcugccccu gcuggugaug      660

aucaucugcu acaccggcau caucaagauc cugcugagaa gacccaacga gaagaagagc      720

aaggccguga gacugaucuu cgugaucaug aucaucuucu uccuguucug gacccccuac      780

aaccugacca uccugaucag cguguuccag gacuuccugu ucacccacga gugcgagcag      840

agcagacacc uggaccuggc cgugcaggug accgagguga ucgccuacac ccacugcugc      900

gugaaccccg ugaucuacgc cuucgugggc gagagauuca gaaaguaccu gagacagcug      960

uuccacagaa gaguggccgu gcaccuggug aaguggcugc ccuuccugag cguggacaga     1020

cuggagagag ugagcagcac cagccccagc accggcgagc acgagcugag cgccggcuuc     1080

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  1834
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt4)

<400>  1834
gggagaaagc uuaccaugag aacccuggcc ugccugcugc ugcugggcug cggcuaccug       60

gcccacgugc uggccgagga ggccgagauc cccagagagg ugaucgagag acuggccaga      120

agccagaucc acagcaucag agaccugcag agacugcugg agaucgacag cgugggcagc      180

gaggacagcc uggacaccag ccugagagcc cacggcgugc acgccaccaa gcacgugccc      240

gagaagagac cccugcccau cagaagaaag agaagcaucg aggaggccgu gcccgccgug      300

ugcaagacca gaaccgugau cuacgagauc cccagaagcc agguggaccc caccagcgcc      360

aacuuccuga ucuggccccc cugcguggag gugaagagau gcaccggcug cugcaacacc      420

agcagcguga agugccagcc cagcagagug caccacagaa gcgugaaggu ggccaaggug      480

gaguacguga gaaagaagcc caagcugaag gaggugcagg ugagacugga ggagcaccug      540

gagugcgccu gcgccaccac cagccugaac cccgacuaca gagaggagga caccggcaga      600

cccagagaga gcggcaagaa gagaaagaga aagagacuga agcccaccug aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  1835
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt4)

<400>  1835
gggagaaagc uuaccaugaa cagaugcugg gcccuguucc ugagccugug cugcuaccug       60

agacugguga gcgccgaggg cgaccccauc cccgaggagc uguacgagau gcugagcgac      120

cacagcauca gaagcuucga cgaccugcag agacugcugc acggcgaccc cggcgaggag      180

gacggcgccg agcuggaccu gaacaugacc agaagccaca gcggcggcga gcuggagagc      240

cuggccagag gcagaagaag ccugggcagc cugaccaucg ccgagcccgc caugaucgcc      300

gagugcaaga ccagaaccga gguguucgag aucagcagaa gacugaucga cagaaccaac      360

gccaacuucc ugguguggcc ccccugcgug gaggugcaga gaugcagcgg cugcugcaac      420

aacagaaacg ugcagugcag acccacccag gugcagcuga gacccgugca ggugagaaag      480

aucgagaucg ugagaaagaa gcccaucuuc aagaaggcca ccgugacccu ggaggaccac      540

cuggccugca agugcgagac cguggccgcc gccagacccg ugaccagaag ccccggcggc      600

agccaggagc agagagccaa gaccccccag accagaguga ccaucagaac cgugagagug      660

agaagacccc ccaagggcaa gcacagaaag uucaagcaca cccacgacaa gaccgcccug      720

aaggagaccc ugggcgccug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  1836
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt4)

<400>  1836
gggagaaagc uuaccaugag ccuguucggc cugcugcugc ugaccagcgc ccuggccggc       60

cagagacagg gcacccaggc cgagagcaac cugagcagca aguuccaguu cagcagcaac      120

aaggagcaga acggcgugca ggacccccag cacgagagaa ucaucaccgu gagcaccaac      180

ggcagcaucc acagccccag auucccccac accuacccca gaaacaccgu gcuggugugg      240

agacuggugg ccguggagga gaacgugugg auccagcuga ccuucgacga gagauucggc      300

cuggaggacc ccgaggacga caucugcaag uacgacuucg uggaggugga ggagcccagc      360

gacggcacca uccugggcag auggugcggc agcggcaccg ugcccggcaa gcagaucagc      420

aagggcaacc agaucagaau cagauucgug agcgacgagu acuuccccag cgagcccggc      480

uucugcaucc acuacaacau cgugaugccc caguucaccg aggccgugag ccccagcgug      540

cugcccccca gcgcccugcc ccuggaccug cugaacaacg ccaucaccgc cuucagcacc      600

cuggaggacc ugaucagaua ccuggagccc gagagauggc agcuggaccu ggaggaccug      660

uacagaccca ccuggcagcu gcugggcaag gccuucgugu ucggcagaaa gagcagagug      720

guggaccuga accugcugac cgaggaggug agacuguaca gcugcacccc cagaaacuuc      780

agcgugagca ucagagagga gcugaagaga accgacacca ucuucuggcc cggcugccug      840

cuggugaaga gaugcggcgg caacugcgcc ugcugccugc acaacugcaa cgagugccag      900

ugcgugccca gcaaggugac caagaaguac cacgaggugc ugcagcugag acccaagacc      960

ggcgugagag gccugcacaa gagccugacc gacguggccc uggagcacca cgaggagugc     1020

gacugcgugu gcagaggcag caccggcggc ugaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  1837
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt4)

<400>  1837
gggagaaagc uuaccaugca cagacugauc uucguguaca cccugaucug cgccaacuuc       60

ugcagcugca gagacaccag cgccaccccc cagagcgcca gcaucaaggc ccugagaaac      120

gccaaccuga gaagagacga ccuguacaga agagacgaga ccauccaggu gaagggcaac      180

ggcuacgugc agagccccag auuccccaac agcuacccca gaaaccugcu gcugaccugg      240

agacugcaca gccaggagaa caccagaauc cagcuggugu ucgacaacca guucggccug      300

gaggaggccg agaacgacau cugcagauac gacuucgugg agguggagga caucagcgag      360

accagcacca ucaucagagg cagauggugc ggccacaagg aggugccccc cagaaucaag      420

agcagaacca accagaucaa gaucaccuuc aagagcgacg acuacuucgu ggccaagccc      480

ggcuucaaga ucuacuacag ccugcuggag gacuuccagc ccgccgccgc cagcgagacc      540

aacugggaga gcgugaccag cagcaucagc ggcgugagcu acaacagccc cagcgugacc      600

gaccccaccc ugaucgccga cgcccuggac aagaagaucg ccgaguucga caccguggag      660

gaccugcuga aguacuucaa ccccgagagc uggcaggagg accuggagaa cauguaccug      720

gacaccccca gauacagagg cagaagcuac cacgacagaa agagcaaggu ggaccuggac      780

agacugaacg acgacgccaa gagauacagc ugcaccccca gaaacuacag cgugaacauc      840

agagaggagc ugaagcuggc caacguggug uucuucccca gaugccugcu ggugcagaga      900

ugcggcggca acugcggcug cggcaccgug aacuggagaa gcugcaccug caacagcggc      960

aagaccguga agaaguacca cgaggugcug caguucgagc ccggccacau caagagaaga     1020

ggcagagcca agaccauggc ccugguggac auccagcugg accaccacga gagaugcgac     1080

ugcaucugca gcagcagacc ccccagauga ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  1838
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt4)

<400>  1838
gggagaaagc uuaccauggu gacccacagc aaguuccccg ccgccggcau gagcagaccc       60

cuggacacca gccugagacu gaagaccuuc agcagcaaga gcgaguacca gcugguggug      120

aacgccguga gaaagcugca ggagagcggc uucuacugga gcgccgugac cggcggcgag      180

gccaaccugc ugcugagcgc cgagcccgcc ggcaccuucc ugaucagaga cagcagcgac      240

cagagacacu ucuucacccu gagcgugaag acccagagcg gcaccaagaa ccugagaauc      300

cagugcgagg gcggcagcuu cagccugcag agcgacccca gaagcaccca gcccgugccc      360

agauucgacu gcgugcugaa gcuggugcac cacuacaugc ccccccccgg cgcccccagc      420

uuccccagcc cccccaccga gcccagcagc gaggugcccg agcagcccag cgcccagccc      480

cugcccggca gcccccccag aagagccuac uacaucuaca gcggcggcga gaagaucccc      540

cuggugcuga gcagaccccu gagcagcaac guggccaccc ugcagcaccu gugcagaaag      600

accgugaacg gccaccugga cagcuacgag aaggugaccc agcugcccgg ccccaucaga      660

gaguuccugg accaguacga cgccccccug ugaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  1839
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt4)

<400>  1839
gggagaaagc uuaccauggu gcccagcgcc ggccagcugg cccuguucgc ccugggcauc       60

gugcuggccg ccugccaggc ccuggagaac agcaccagcc cccugagcgc cgaccccccc      120

guggccgccg ccguggugag ccacuucaac gacugccccg acagccacac ccaguucugc      180

uuccacggca ccugcagauu ccuggugcag gaggacaagc ccgccugcgu gugccacagc      240

ggcuacgugg gcgccagaug cgagcacgcc gaccugcugg ccgugguggc cgccagccag      300

aagaagcagg ccaucaccgc ccugguggug gugagcaucg uggcccuggc cgugcugauc      360

aucaccugcg ugcugaucca cugcugccag gugagaaagc acugcgagug gugcagagcc      420

cugaucugca gacacgagaa gcccagcgcc cugcugaagg gcagaaccgc cugcugccac      480

agcgagaccg uggugugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  1840
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt4)

<400>  1840
gggagaaagc uuaccaugcc ccccagcggc cugagacugc ugccccugcu gcugccccug       60

cuguggcugc uggugcugac ccccggcaga cccgccgccg gccugagcac cugcaagacc      120

aucgacaugg agcuggugaa gagaaagaga aucgaggcca ucagaggcca gauccugagc      180

aagcugagac uggccagccc ccccagccag ggcgaggugc cccccggccc ccugcccgag      240

gccgugcugg cccuguacaa cagcaccaga gacagagugg ccggcgagag cgccgagccc      300

gagcccgagc ccgaggccga cuacuacgcc aaggagguga ccagagugcu gaugguggag      360

acccacaacg agaucuacga caaguucaag cagagcaccc acagcaucua cauguucuuc      420

aacaccagcg agcugagaga ggccgugccc gagcccgugc ugcugagcag agccgagcug      480

agacugcuga gacugaagcu gaagguggag cagcacgugg agcuguacca gaaguacagc      540

aacaacagcu ggagauaccu gagcaacaga cugcuggccc ccagcgacag ccccgagugg      600

cugagcuucg acgugaccgg cguggugaga caguggcuga gcagaggcgg cgagaucgag      660

ggcuucagac ugagcgccca cugcagcugc gacagcagag acaacacccu gcagguggac      720

aucaacggcu ucaccaccgg cagaagaggc gaccuggcca ccauccacgg caugaacaga      780

cccuuccugc ugcugauggc caccccccug gagagagccc agcaccugca gagcagcaga      840

cacagaagag cccuggacac caacuacugc uucagcagca ccgagaagaa cugcugcgug      900

agacagcugu acaucgacuu cagaaaggac cugggcugga aguggaucca cgagcccaag      960

ggcuaccacg ccaacuucug ccugggcccc ugccccuaca ucuggagccu ggacacccag     1020

uacagcaagg ugcuggcccu guacaaccag cacaaccccg gcgccagcgc cgcccccugc     1080

ugcgugcccc aggcccugga gccccugccc aucguguacu acgugggcag aaagcccaag     1140

guggagcagc ugagcaacau gaucgugaga agcugcaagu gcagcugagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  1841
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt4)

<400>  1841
gggagaaagc uuaccaugca cuacugcgug cugagcgccu uccugauccu gcaccuggug       60

accguggccc ugagccugag caccugcagc acccuggaca uggaccaguu caugagaaag      120

agaaucgagg ccaucagagg ccagauccug agcaagcuga agcugaccag cccccccgag      180

gacuaccccg agcccgagga ggugcccccc gaggugauca gcaucuacaa cagcaccaga      240

gaccugcugc aggagaaggc cagcagaaga gccgccgccu gcgagagaga gagaagcgac      300

gaggaguacu acgccaagga gguguacaag aucgacaugc cccccuucuu ccccagcgag      360

aacgccaucc cccccaccuu cuacagaccc uacuucagaa ucgugagauu cgacgugagc      420

gccauggaga agaacgccag caaccuggug aaggccgagu ucagaguguu cagacugcag      480

aaccccaagg ccagagugcc cgagcagaga aucgagcugu accagauccu gaagagcaag      540

gaccugacca gccccaccca gagauacauc gacagcaagg uggugaagac cagagccgag      600

ggcgaguggc ugagcuucga cgugaccgac gccgugcacg aguggcugca ccacaaggac      660

agaaaccugg gcuucaagau cagccugcac ugccccugcu gcaccuucgu gcccagcaac      720

aacuacauca uccccaacaa gagcgaggag cuggaggcca gauucgccgg caucgacggc      780

accagcaccu acaccagcgg cgaccagaag accaucaaga gcaccagaaa gaagaacagc      840

ggcaagaccc cccaccugcu gcugaugcug cugcccagcu acagacugga gagccagcag      900

accaacagaa gaaagaagag agcccuggac gccgccuacu gcuucagaaa cgugcaggac      960

aacugcugcc ugagaccccu guacaucgac uucaagagag accugggcug gaaguggauc     1020

cacgagccca agggcuacaa cgccaacuuc ugcgccggcg ccugccccua ccuguggagc     1080

agcgacaccc agcacagcag agugcugagc cuguacaaca ccaucaaccc cgaggccagc     1140

gccagccccu gcugcgugag ccaggaccug gagccccuga ccauccugua cuacaucggc     1200

aagaccccca agaucgagca gcugagcaac augaucguga agagcugcaa gugcagcuga     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  1842
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt4)

<400>  1842
gggagaaagc uuaccaugaa gaugcaccug cagagagccc ugguggugcu ggcccugcug       60

aacuucgcca ccgugagccu gagccugagc accugcacca cccuggacuu cggccacauc      120

aagaagaaga gaguggaggc caucagaggc cagauccuga gcaagcugag acugaccagc      180

ccccccgagc ccaccgugau gacccacgug cccuaccagg ugcuggcccu guacaacagc      240

accagagagc ugcuggagga gaugcacggc gagagagagg agggcugcac ccaggagaac      300

accgagagcg aguacuacgc caaggagauc cacaaguucg acaugaucca gggccuggcc      360

gagcacaacg agcuggccgu gugccccaag ggcaucacca gcaagguguu cagauucaac      420

gugagcagcg uggagaagaa cagaaccaac cuguucagag ccgaguucag agugcugaga      480

gugcccaacc ccagcagcaa gagaaacgag cagagaaucg agcuguucca gauccugaga      540

cccgacgagc acaucgccaa gcagagauac aucggcggca agaaccugcc caccagaggc      600

accgccgagu ggcugagcuu cgacgugacc gacaccguga gagaguggcu gcugagaaga      660

gagagcaacc ugggccugga gaucagcauc cacugccccu gccacaccuu ccagcccaac      720

ggcgacaucc uggagaacau ccacgaggug auggagauca aguucaaggg cguggacaac      780

gaggacgacc acggcagagg cgaccugggc agacugaaga agcagaagga ccaccacaac      840

ccccaccuga uccugaugau gauccccccc cacagacugg acaaccccgg ccagggcggc      900

cagagaaaga agagagcccu ggacaccaac uacugcuuca gaaaccugga ggagaacugc      960

ugcgugagac cccuguacau cgacuucaga caggaccugg gcuggaagug ggugcacgag     1020

cccaagggcu acuacgccaa cuucugcagc ggccccugcc ccuaccugag aagcgccgac     1080

accacccaca gcaccgugcu gggccuguac aacacccuga accccgaggc cagcgccagc     1140

cccugcugcg ugccccagga ccuggagccc cugaccaucc uguacuacgu gggcagaacc     1200

cccaaggugg agcagcugag caacauggug gugaagagcu gcaagugcag cugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  1843
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt4)

<400>  1843
gggagaaagc uuaccauggc ccccguggcc gugugggccg cccuggccgu gggccuggag       60

cugugggccg ccgcccacgc ccugcccgcc cagguggccu ucacccccua cgcccccgag      120

cccggcagca ccugcagacu gagagaguac uacgaccaga ccgcccagau gugcugcagc      180

aagugcagcc ccggccagca cgccaaggug uucugcacca agaccagcga caccgugugc      240

gacagcugcg aggacagcac cuacacccag cuguggaacu gggugcccga gugccugagc      300

ugcggcagca gaugcagcag cgaccaggug gagacccagg ccugcaccag agagcagaac      360

agaaucugca ccugcagacc cggcugguac ugcgcccuga gcaagcagga gggcugcaga      420

cugugcgccc cccugagaaa gugcagaccc ggcuucggcg uggccagacc cggcaccgag      480

accagcgacg uggugugcaa gcccugcgcc cccggcaccu ucagcaacac caccagcagc      540

accgacaucu gcagacccca ccagaucugc aacguggugg ccauccccgg caacgccagc      600

auggacgccg ugugcaccag caccagcccc accagaagca uggcccccgg cgccgugcac      660

cugccccagc ccgugagcac cagaagccag cacacccagc ccacccccga gcccagcacc      720

gcccccagca ccagcuuccu gcugcccaug ggccccagcc cccccgccga gggcagcacc      780

ggcgacuucg cccugcccgu gggccugauc gugggcguga ccgcccuggg ccugcugauc      840

aucggcgugg ugaacugcgu gaucaugacc caggugaaga agaagccccu gugccugcag      900

agagaggcca aggugcccca ccugcccgcc gacaaggcca gaggcaccca gggccccgag      960

cagcagcacc ugcugaucac cgcccccagc agcagcagca gcagccugga gagcagcgcc     1020

agcgcccugg acagaagagc ccccaccaga aaccagcccc aggcccccgg cguggaggcc     1080

agcggcgccg gcgaggccag agccagcacc ggcagcagcg acagcagccc cggcggccac     1140

ggcacccagg ugaacgugac cugcaucgug aacgugugca gcagcagcga ccacagcagc     1200

cagugcagca gccaggccag cagcaccaug ggcgacaccg acagcagccc cagcgagagc     1260

cccaaggacg agcaggugcc cuucagcaag gaggagugcg ccuucagaag ccagcuggag     1320

acccccgaga cccugcuggg cagcaccgag gagaagcccc ugccccuggg cgugcccgac     1380

gccggcauga agcccagcug aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  1844
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt4)

<400>  1844
gggagaaagc uuaccaugcc cgugaugaga cuguuccccu gcuuccugca gcugcuggcc       60

ggccuggccc ugcccgccgu gcccccccag cagugggccc ugagcgccgg caacggcagc      120

agcgaggugg agguggugcc cuuccaggag guguggggca gaagcuacug cagagcccug      180

gagagacugg uggacguggu gagcgaguac cccagcgagg uggagcacau guucagcccc      240

agcugcguga gccugcugag augcaccggc ugcugcggcg acgagaaccu gcacugcgug      300

cccguggaga ccgccaacgu gaccaugcag cugcugaaga ucagaagcgg cgacagaccc      360

agcuacgugg agcugaccuu cagccagcac gugagaugcg agugcagacc ccugagagag      420

aagaugaagc ccgagagaag aagacccaag ggcagaggca agagaagaag agagaagcag      480

agacccaccg acugccaccu gugcggcgac gccgugccca gaagaugagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  1845
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt4)

<400>  1845
gggagaaagc uuaccaugac cgacagacag accgacaccg cccccagccc cagcuaccac       60

cugcugcccg gcagaagaag aaccguggac gccgccgcca gcagaggcca gggccccgag      120

cccgcccccg gcggcggcgu ggagggcgug ggcgccagag gcguggcccu gaagcuguuc      180

gugcagcugc ugggcugcag cagauucggc ggcgccgugg ugagagccgg cgaggccgag      240

cccagcggcg ccgccagaag cgccagcagc ggcagagagg agccccagcc cgaggagggc      300

gaggaggagg aggagaagga ggaggagaga ggcccccagu ggagacuggg cgccagaaag      360

cccggcagcu ggaccggcga ggccgccgug ugcgccgaca gcgcccccgc cgccagagcc      420

ccccaggccc uggccagagc cagcggcaga ggcggcagag uggccagaag aggcgccgag      480

gagagcggcc ccccccacag ccccagcaga agaggcagcg ccagcagagc cggccccggc      540

agagccagcg agaccaugaa cuuccugcug agcugggugc acuggagccu ggcccugcug      600

cuguaccugc accacgccaa guggagccag gccgccccca uggccgaggg cggcggccag      660

aaccaccacg agguggugaa guucauggac guguaccaga gaagcuacug ccaccccauc      720

gagacccugg uggacaucuu ccaggaguac cccgacgaga ucgaguacau cuucaagccc      780

agcugcgugc cccugaugag augcggcggc ugcugcaacg acgagggccu ggagugcgug      840

cccaccgagg agagcaacau caccaugcag aucaugagaa ucaagcccca ccagggccag      900

cacaucggcg agaugagcuu ccugcagcac aacaagugcg agugcagacc caagaaggac      960

agagccagac aggagaagaa gagcgugaga ggcaagggca agggccagaa gagaaagaga     1020

aagaagagca gauacaagag cuggagcgug uacgugggcg ccagaugcug ccugaugccc     1080

uggagccugc ccggccccca ccccugcggc cccugcagcg agagaagaaa gcaccuguuc     1140

gugcaggacc cccagaccug caagugcagc ugcaagaaca ccgacagcag augcaaggcc     1200

agacagcugg agcugaacga gagaaccugc agaugcgaca agcccagaag augaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  1846
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt4)

<400>  1846
gggagaaagc uuaccaugaa cuuccugcug agcugggugc acuggagccu ggcccugcug       60

cuguaccugc accacgccaa guggagccag gccgccccca uggccgaggg cggcggccag      120

aaccaccacg agguggugaa guucauggac guguaccaga gaagcuacug ccaccccauc      180

gagacccugg uggacaucuu ccaggaguac cccgacgaga ucgaguacau cuucaagccc      240

agcugcgugc cccugaugag augcggcggc ugcugcaacg acgagggccu ggagugcgug      300

cccaccgagg agagcaacau caccaugcag aucaugagaa ucaagcccca ccagggccag      360

cacaucggcg agaugagcuu ccugcagcac aacaagugcg agugcagacc caagaaggac      420

agagccagac aggagaagaa gagcgugaga ggcaagggca agggccagaa gagaaagaga      480

aagaagagca gauacaagag cuggagcgug uacgugggcg ccagaugcug ccugaugccc      540

uggagccugc ccggccccca ccccugcggc cccugcagcg agagaagaaa gcaccuguuc      600

gugcaggacc cccagaccug caagugcagc ugcaagaaca ccgacagcag augcaaggcc      660

agacagcugg agcugaacga gagaaccugc agaugcgaca agcccagaag augaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  1847
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt4)

<400>  1847
gggagaaagc uuaccaugag cccccugcug agaagacugc ugcuggccgc ccugcugcag       60

cuggcccccg cccaggcccc cgugagccag cccgacgccc ccggccacca gagaaaggug      120

gugagcugga ucgacgugua caccagagcc accugccagc ccagagaggu gguggugccc      180

cugaccgugg agcugauggg caccguggcc aagcagcugg ugcccagcug cgugaccgug      240

cagagaugcg gcggcugcug ccccgacgac ggccuggagu gcgugcccac cggccagcac      300

caggugagaa ugcagauccu gaugaucaga uaccccagca gccagcuggg cgagaugagc      360

cuggaggagc acagccagug cgagugcaga cccaagaaga aggacagcgc cgugaagccc      420

gacagagccg ccacccccca ccacagaccc cagcccagaa gcgugcccgg cugggacagc      480

gcccccggcg cccccagccc cgccgacauc acccacccca cccccgcccc cggccccagc      540

gcccacgccg cccccagcac caccagcgcc cugacccccg gccccgccgc cgccgccgcc      600

gacgccgccg ccagcagcgu ggccaagggc ggcgccugag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  1848
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt4)

<400>  1848
gggagaaagc uuaccaugca ccugcugggc uucuucagcg uggccugcag ccugcuggcc       60

gccgcccugc ugcccggccc cagagaggcc cccgccgccg ccgccgccuu cgagagcggc      120

cuggaccuga gcgacgccga gcccgacgcc ggcgaggcca ccgccuacgc cagcaaggac      180

cuggaggagc agcugagaag cgugagcagc guggacgagc ugaugaccgu gcuguacccc      240

gaguacugga agauguacaa gugccagcug agaaagggcg gcuggcagca caacagagag      300

caggccaacc ugaacagcag aaccgaggag accaucaagu ucgccgccgc ccacuacaac      360

accgagaucc ugaagagcau cgacaacgag uggagaaaga cccagugcau gcccagagag      420

gugugcaucg acgugggcaa ggaguucggc guggccacca acaccuucuu caagcccccc      480

ugcgugagcg uguacagaug cggcggcugc ugcaacagcg agggccugca gugcaugaac      540

accagcacca gcuaccugag caagacccug uucgagauca ccgugccccu gagccagggc      600

cccaagcccg ugaccaucag cuucgccaac cacaccagcu gcagaugcau gagcaagcug      660

gacguguaca gacaggugca cagcaucauc agaagaagcc ugcccgccac ccugccccag      720

ugccaggccg ccaacaagac cugccccacc aacuacaugu ggaacaacca caucugcaga      780

ugccuggccc aggaggacuu cauguucagc agcgacgccg gcgacgacag caccgacggc      840

uuccacgaca ucugcggccc caacaaggag cuggacgagg agaccugcca gugcgugugc      900

agagccggcc ugagacccgc cagcugcggc ccccacaagg agcuggacag aaacagcugc      960

cagugcgugu gcaagaacaa gcuguucccc agccagugcg gcgccaacag agaguucgac     1020

gagaacaccu gccagugcgu gugcaagaga accugcccca gaaaccagcc ccugaacccc     1080

ggcaagugcg ccugcgagug caccgagagc ccccagaagu gccugcugaa gggcaagaag     1140

uuccaccacc agaccugcag cugcuacaga agacccugca ccaacagaca gaaggccugc     1200

gagcccggcu ucagcuacag cgaggaggug ugcagaugcg ugcccagcua cuggaagaga     1260

ccccagauga gcugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  1849
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt4)

<400>  1849
gggagaaagc uuaccaugua cagagagugg guggugguga acguguucau gaugcuguac       60

gugcagcugg ugcagggcag cagcaacgag cacggccccg ugaagagaag cagccagagc      120

acccuggaga gaagcgagca gcagaucaga gccgccagca gccuggagga gcugcugaga      180

aucacccaca gcgaggacug gaagcugugg agaugcagac ugagacugaa gagcuucacc      240

agcauggaca gcagaagcgc cagccacaga agcaccagau ucgccgccac cuucuacgac      300

aucgagaccc ugaaggugau cgacgaggag uggcagagaa cccagugcag ccccagagag      360

accugcgugg agguggccag cgagcugggc aagagcacca acaccuucuu caagcccccc      420

ugcgugaacg uguucagaug cggcggcugc ugcaacgagg agagccugau cugcaugaac      480

accagcacca gcuacaucag caagcagcug uucgagauca gcgugccccu gaccagcgug      540

cccgagcugg ugcccgugaa gguggccaac cacaccggcu gcaagugccu gcccaccgcc      600

cccagacacc ccuacagcau caucagaaga agcauccaga uccccgagga ggacagaugc      660

agccacagca agaagcugug ccccaucgac augcuguggg acagcaacaa gugcaagugc      720

gugcugcagg aggagaaccc ccuggccggc accgaggacc acagccaccu gcaggagccc      780

gcccugugcg gcccccacau gauguucgac gaggacagau gcgagugcgu gugcaagacc      840

cccugcccca aggaccugau ccagcacccc aagaacugca gcugcuucga gugcaaggag      900

agccuggaga ccugcugcca gaagcacaag cuguuccacc ccgacaccug cagcugcgag      960

gacagaugcc ccuuccacac cagacccugc gccagcggca agaccgccug cgccaagcac     1020

ugcagauucc ccaaggagaa gagagccgcc cagggccccc acagcagaaa gaaccccuga     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  1850
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt5)

<400>  1850
gggagaaagc uuaccaugga cagcgaugag accggcuucg aacacuccgg gcugugggug       60

ucuguccucg ccggacugcu ucugggcgcu ugccaggccc aucccauccc ugacagcucc      120

ccgcuccugc aauuuggggg acagguuaga cagcgguacc uuuauacaga ugacgcgcag      180

caaacggagg cucaccugga aauucgcgag gauggcaccg ugggcggagc cgccgaccag      240

ucucccgaaa gccuccugca gcugaaggcu cucaaaccug gcgugaucca gauucugggc      300

gucaagacau ccagauuccu uugucaacgg cccgaugggg cccuguacgg aucucuccau      360

uuugacccug aggcuugcag cuuccgcgag cugcuucugg aagauggcua uaacguguac      420

caguccgagg cccacgggcu cccccugcau cugccuggaa auaaaagccc gcacagagac      480

cccgcgccuc ggggccccgc ccgcuuucuc ccucugcccg ggcuuccgcc ugcucugccc      540

gaaccucccg gaauccucgc uccccagccu ccggauguug ggucuuccga cccccugagc      600

auggugggcc cuucucaggg gagauccccc agcuaugccu cuugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  1851
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt5)

<400>  1851
gggagaaagc uuaccaugca cagcuuuccc ccucugcucc ugcuucuguu cuggggcgug       60

gucucccauu cuuucccggc cacccucgag acacaggaac aagacguuga ucuggugcag      120

aaguaccuug agaaauauua caaccugaag aaugacggga gacaggugga aaaacggcgc      180

aacagcggac ccgucgugga gaagcucaaa cagaugcaag aauuuuucgg ccugaagguu      240

acggggaagc cugaugcuga gacccugaaa gugaugaagc agcccagaug cggagucccu      300

gacguggccc aguuuguucu cacagagggc aauccccggu gggaacagac ccaccugaca      360

uaucgcaucg agaacuacac cccugaucuu ccgagagcgg acguggauca ugcuauugaa      420

aaagccuucc aacugugguc caaugucaca ccccucaccu uuacgaaggu gucugagggg      480

caggccgaca ucaugauuag cuucgugcgg ggagaucacc gcgacaacuc cccuuuugau      540

ggccccggcg ggaaucuggc ucaugccuuc cagccuggac ccggcaucgg gggagacgcu      600

cacuuugaug aggacgaaag auggaccaac aauuuccggg aguauaaccu ucaccgcguc      660

gccgcgcaug aacugggcca cucucucggg cugagccauu ccacagacau uggagcccug      720

auguacccga gcuauaccuu uucuggcgau guucagcucg cucaagacga uaucgacggc      780

auccaggcca uuuacgggag aucccagaau ccugugcaac ccaucggacc ucagacaccc      840

aaggcuugug auagcaaacu gaccuucgac gccauuacga caauccgggg cgaggugaug      900

uucuuuaagg aucgcuucua caugagaacc aaccccuuuu auccugaagu cgagcuuaau      960

uucauuucug uguuuuggcc gcagcugccc aacgggcucg aggcggccua cgaguucgcu     1020

gaccgggaug aaguucgcuu uuucaaagga aauaaguauu gggccgugca gggccaaaac     1080

guccugcacg gguacccuaa agacaucuau uccagcuuug gauuccccag aacagugaag     1140

cacauugaug cugcccuuuc ugaagagaac accggcaaaa ccuacuuuuu cguugccaau     1200

aaguauuggc gguacgacga auacaaaaga uccauggacc cuggcuaucc caagaugauc     1260

gcucaugauu uuccggggau cggacacaag guggacgcgg ucuucaugaa agauggcuuc     1320

uuuuacuucu uucaugggac acgccaguau aaguucgacc cuaaaacgaa gcggauucug     1380

acccuccaga aagccaacag cugguuuaau ugcagaaaga acugaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  1852
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt5)

<400>  1852
gggagaaagc uuaccaugca cagcuuuccc ccucugcucc ugcuucuguu cuggggcgug       60

gucucccauu cuuucguucu caccgagggg aacccgagau gggaacagac acaccugacg      120

uaccggauug agaauuauac ccccgaccuu ccucgcgccg auguggacca ugcuauugaa      180

aaggccuuuc aacuguggag caacgugaca ccccucaccu ucacaaaagu cuccgaggga      240

caggcggaua ucaugauuuc uuuugugaga ggcgaccacc gggauaauag cccuuucgac      300

gggcccggag gcaaccuggc ucaugccuuu cagccugggc cgggaaucgg cggcgaugcc      360

cacuucgacg aagaugagcg cuggaccaau aacuuuagag aguacaaucu gcaccggguu      420

gcugcccaug aacucgggca cucccuggga cuuucucaua gcacagacau uggcgcucug      480

auguaucccu ccuacaccuu cagcggggau gugcagcucg cccaagacga uaucgacgga      540

auccaggcga uuuauggccg cucucagaac ccuguccagc ccaucgggcc ucaaacgccc      600

aaggccugcg acuccaaacu gaccuuugau gcuauuacaa ccaucagagg agaggugaug      660

uucuuuaagg accgguucua caugcgcaca aauccguucu auccugaagu ugagcuuaac      720

uuuauuagcg uguucuggcc ccagcugccu aauggccucg aggccgcuua cgaauuugcc      780

gauagagacg agguccgguu cuuuaaaggc aacaaguacu gggcggugca ggggcagaau      840

gugcugcacg gauaucccaa ggauaucuac ucuuccuucg gcuuuccccg caccgucaaa      900

cacauugacg ccgcucugag cgaagagaac acggggaaga cauauuucuu uguugccaau      960

aaauacugga gauaugauga auacaagcgg ucuauggacc cuggauaucc gaaaaugauc     1020

gcucaugauu uccccggcau cgggcacaag guggacgccg uguuuaugaa ggauggauuc     1080

uuuuacuucu uccauggcac ccgccaauac aaauuugacc cuaagacaaa aagaauccuc     1140

acccugcaga aggccaacuc cugguucaac ugucggaaaa auugaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  1853
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt5)

<400>  1853
gggagaaagc uuaccaugaa gaaaaacauc cugaagauuc ucauggacag cuacuccaaa       60

gagucuaaga uccagaccgu gagacggguc acaagcguuu cccugcuugc cguguaucug      120

acgaugaaua ccucuagccu cgugcuggcu aaacccauug aaaacacaaa ugauaccucc      180

aucaagaacg ucgagaaacu ucgcaaugcc ccuaacgaag aaaauucuaa aaagguggaa      240

gacagcaaaa acgauaaggu ugagcacgug aaaaauauug aggaagcgaa ggucgagcaa      300

guggcuccgg aaguuaaguc caaaagcaca cugagaucug ccuccaucgc caacaccaau      360

agcgagaagu acgacuucga guaucucaac ggccugucuu acacagaacu gaccaaucuc      420

aucaaaaaca uuaaguggaa ucagaucaac gggcuguuua acuauuccac gggaagccag      480

aaauucuuug gcgauaagaa ucgggugcag gcuauuauca acgcccuuca agagucuggg      540

cgcaccuaca cagcuaauga caugaaagga auugaaaccu ucacagaggu ccugagagcc      600

ggcuuuuauc ucggguacua caacgaugga cuguccuauc uuaaugaccg gaacuuccag      660

gauaagugca uccccgcgau gauugccauc cagaagaauc cuaacuuuaa acugggcacc      720

gcugugcagg acgaagugau cacgagccuc ggcaagcuga uugggaaugc cuccgcuaac      780

gccgaggucg uuaauaacug ugugcccgug cugaaacaau uccgcgagaa ucucaaccag      840

uacgcgccug auuaugucaa gggaacagcc gugaaugaac ugaucaaagg cauugaguuu      900

gacuucucug gggcugccua cgaaaaggau guuaagacca ugcccuggua uggaaaaauc      960

gacccuuuua uuaacgagcu uaaggcucug ggccucuacg ggaacaucac aagcgccacc     1020

gaaugggccu ccgacguggg aaucuauuac cugagcaaau ucggccuuua cucuaccaau     1080

agaaacgaua uuguccaguc ccuggagaag gcuguggaca uguauaaaua cggcaagauc     1140

gcguuuguug ccauggagcg gauuacaugg gauuaugacg ggaucggaag caauggcaag     1200

aaaguggauc augacaaguu ccucgaugac gcugaaaaac acuaccugcc gaagacguau     1260

accuucgaua acgggacauu uauuauccgc gccggagaca aagucucuga ggaaaagauc     1320

aagagacugu acugggccag ccgggaggug aaaucccagu uccaucgcgu cgugggcaau     1380

gauaaggcuc ucgaaguugg gaacgccgac gacgugcuga ccaugaaaau uuuuaauucu     1440

cccgaggagu auaaguucaa cacaaauauc aacggaguca gcaccgauaa uggcggccuu     1500

uacauugaac cuagagggac guuuuacaca uaugagcgga caccccaaca guccaucuuc     1560

agccuggagg agcucuuucg ccacgaguac acccauuauc ugcaggcgag auaccuugug     1620

gacggacugu ggggccaagg gccuuucuau gagaaaaacc ggcucaccug guuugaugaa     1680

ggaaccgcug aguucuuugc cggcucuaca agaacguccg ggguucugcc ccgcaagagc     1740

auucugggcu accucgccaa agacaaggug gaucaccggu auucucugaa gaaaacccuu     1800

aauuccggau acgacgauag cgacuggaug uucuacaacu auggcuuugc ugucgcccac     1860

uaccuguaug aaaaggauau gccgacauuc aucaaaauga auaaggcuau ucucaacacc     1920

gacgugaaau ccuacgauga aaucaucaag aagcugucug acgaugccaa caaaaauaca     1980

gaguaucaga accauauuca ggagcuggcg gacaaguacc agggggccgg aaucccucuu     2040

gugagcgacg auuaucucaa agaccacggc uacaagaagg cuuccgaagu uuacucugag     2100

auuagcaagg ccgcuucccu gaccaauacg agcgucaccg ccgaaaaguc ucaauauuuc     2160

aacacauuua cccugagagg gacauacacc ggagagacgu ccaaaggcga guucaaggau     2220

ugggacgaaa ugagcaaaaa gcucgauggg acacuggagu cucuugcgaa aaauuccugg     2280

agcggcuaua agacccugac agccuacuuu accaacuauc gcgugaccuc ugacaauaag     2340

gugcaguacg augucguguu ccauggaguu cucacagaca acgcugauau cagcaauaac     2400

aaagccccca uugcuaaggu gacgggcccu uccaccgggg ccgucggacg gaauaucgaa     2460

uuuagcggca aagacucuaa ggaugaggac gggaaaaucg uguccuauga uugggacuuc     2520

ggagacggcg ccacaagcag agggaagaac uccguucacg cuuacaaaaa ggcgggcacc     2580

uacaauguga cacugaaggu caccgaugac aaaggagcca cggcuacaga aucuuuuacc     2640

auugagauca agaacgaaga uaccacaacc cccauuacaa aagagaugga gcccaaugac     2700

gauaucaagg aagccaacgg cccuauugug gaggggguua cggugaaagg agaccugaac     2760

ggcagcgaug acgccgauac cuucuauuuu gacgucaagg aagaugggga cgugacaauc     2820

gagcuuccgu acuccggauc uagcaauuuc accuggcucg uguauaagga gggcgacgau     2880

cagaaccaca ucgcuuccgg gauugacaaa aauaacucua aggucggcac auuuaaaagc     2940

accaagggac gccauuacgu uuucaucuau aaacacgauu ccgccagcaa uauuucuuac     3000

ucccugaaca ucaagggccu ggggaaugaa aagcucaaag agaaggaaaa caaugacagc     3060

ucugauaaag cgacggugau ucccaacuuu aauaccacaa ugcagggauc ccugcuuggc     3120

gacgauagcc gggacuauua cucuuucgag gugaaggaag agggggaggu caacaucgaa     3180

cuggauaaaa aggacgaguu cggagugacc uggacacucc auccugaauc caauaucaac     3240

gauagaauua ccuacggcca aguugacggc aauaagguga gcaacaaagu caagcugcgc     3300

cccgggaaau auuaccugcu uguguauaag uacuccggaa gcggcaauua ugagcuccgg     3360

guuaacaaau gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  1854
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt5)

<400>  1854
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuucu guucuccucu       60

gccuacagca uugcuaacac aaauuccgag aaauaugacu uugaauaccu uaacggccug      120

ucuuauacgg agcucaccaa ucugaucaag aacauuaaau ggaaucagau caacgggcuu      180

uucaauuaca gcacaggauc ccaaaaguuu uucggcgaua aaaacagagu ccaggccauu      240

aucaaugcgc ugcaggaauc ugggcggacc uauacagcua acgacaugaa gggaaucgag      300

accuuuacag aaguucuccg cgccggcuuc uaccuggggu auuacaauga uggacugagc      360

uaccucaacg acagaaauuu ucaggauaag ugcauucccg ccaugaucgc uauucagaaa      420

aacccuaauu ucaagcuggg caccgccgug caagacgagg ugaucacguc ccuuggcaaa      480

cugauuggga acgcuagcgc caacgcggag gucgugaaua acuguguucc ggugcucaag      540

caguuucggg aaaaucugaa ccaguaugcc cccgauuacg ucaaaggaac cgcugugaau      600

gagcuuauca agggcauuga guucgacuuu ucuggggccg cuuaugaaaa ggauguuaaa      660

acaaugccuu gguacggaaa gaucgacccc uucaucaacg agcugaaagc ccucggccug      720

uaugggaaua uuaccuccgc gacagaaugg gccagcgaug ugggaaucua cuaucugucu      780

aaguucggcc ucuacuccac caaccgcaau gacauugucc aaagccugga gaaagcugug      840

gauauguaca aguauggcaa aaucgccuuu guggcuaugg aaagaauuac gugggacuac      900

gacgggaucg gaucuaacgg caagaagguc gaucacgaca aauuccuuga ugacgccgag      960

aagcauuauc ugccuaaaac auacaccuuu gauaauggga cauucaucau ucgggccgga     1020

gacaagguuu ccgaagagaa aaucaagcgc cucuauuggg cuagcagaga ggugaagucc     1080

caguuucacc ggguggucgg caacgauaaa gcgcuggaag uggggaaugc cgacgauguu     1140

cuuaccauga agauuuucaa cucucccgag gaauacaaau uuaauaccaa caucaacgga     1200

gugagcacag acaauggcgg ccuguauauu gagccucgcg ggacguucua caccuacgaa     1260

agaacaccgc agcaguccau cuuuagccuc gaggagcugu uccggcauga auauacccac     1320

uaccugcaag cucgcuaucu cgucgaugga cuguggggcc aggggcccuu uuacgagaag     1380

aacagacuua caugguucga cgaaggaacc gccgaguuuu ucgccggcuc uacgcggaca     1440

uccggggugc ugccucgcaa aagcauccuc ggcuaucugg cuaaggacaa gguugaucau     1500

agauacucuc uuaaaaagac ccugaauagc ggauaugacg auuccgacug gauguucuac     1560

aacuacggcu uugccguggc gcacuaucuc uacgaaaaag auaugcccac cuucauuaag     1620

augaauaaag cuauccugaa cacagacguc aagucuuaug augagauuau caagaaacug     1680

agcgacgaug ccaauaagaa caccgaguac cagaaucaca uucaagaacu cgccgacaaa     1740

uaucaggggg cuggaauccc ucuggugucc gaugacuacc uuaaggauca uggcuauaaa     1800

aaggccagcg aggucuacuc ugaaauuucc aaagcugcca gccugacaaa cacgucugug     1860

accgcggaga agucccagua cuuuaauaca uucacccucc gggggacaua uaccggagag     1920

acgagcaagg gcgaauuuaa agacugggac gagaugucca agaaacugga ugggacccug     1980

gaaucucuug ccaagaacag cugguccggc uacaaaacac ucaccgcuua uuucacaaau     2040

uacagaguua ccucugacaa caaggugcag uaugaugucg uguuucacgg aguucugacg     2100

gacaaugccg auaucagcaa caacaaggcu cccaucgcca aagugacagg cccguccacc     2160

ggggcggucg gacgcaauau ugaguucagc ggcaaggacu cuaaagauga agacgggaag     2220

aucguguccu acgauuggga cuuuggagau ggcgccacaa gccgggggaa aaacucugug     2280

caugcuuaua agaaggccgg caccuacaau guuacccuga aagucacaga cgauaaggga     2340

gcuacggcca ccgaguccuu cacaauugag aucaaaaacg aagacaccac aaccccuauu     2400

acgaaggaga uggaacccaa ugacgauauc aaagaggcca acggcccuau cguggaaggg     2460

gugacaguca agggagaccu caauggcagc gaugacgcug auaccuuuua cuucgacgug     2520

aaggaggaug gggacguuac cauugagcug cccuauucug gaagcuccaa cuuuacaugg     2580

cuuguguaca aagaaggcga ugaccaaaau cacaucgcga gcgggauuga uaagaacaau     2640

ucuaaagucg gcaccuucaa guccacaaaa ggaagacacu auguguucau cuacaagcau     2700

gacagcgccu ccaacauuuc uuauagccug aauaucaaag gccucgggaa cgagaagcug     2760

aaggaaaaag agaauaacga cuccucugau aaggcuacgg uuauccccaa cuuuaauacc     2820

acaaugcagg gaagccugcu uggcgacgau ucccgcgacu acuauucuuu cgaagugaaa     2880

gaggaggggg aagucaacau ugagcucgau aagaaagacg aauuuggagu gaccuggaca     2940

cugcacccug agagcaauau caacgaucgg auuaccuacg gccagguuga cggcaauaag     3000

guguccaaca aggucaaacu gagaccgggg aaguacuauc uccuggugua caaauauagc     3060

ggaucuggca auuacgagcu ucgcgugaac aagugaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  1855
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt5)

<400>  1855
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuucu guucuccucu       60

gccuacagca ugaaaaagaa cauucuuaaa auccugaugg acuccuauuc uaaggagagc      120

aaaauucaga cagucagacg gguuacgucc gugucucucc uggcugugua ccuuaccaug      180

aauacaagcu cccugguccu cgccaagccc aucgaaaaca ccaaugauac aagcauuaag      240

aacguggaga aacugcgcaa ugcgccuaac gaagaaaauu cuaagaaagu ugaagacucc      300

aagaacgaua aaguggagca cgucaagaau aucgaggaag cuaaggugga gcaaguugcc      360

ccggaaguga aaagcaaguc uacccugaga uccgccagcc ggcgcagacg gaaacgcauc      420

gcuaacacaa auucugagaa guaugacuuu gaguaccuca acggccuguc cuauaccgaa      480

cuuacgaauc ugauuaaaaa caucaagugg aaucagauua acggacucuu caacuacagc      540

accggauccc agaaauuuuu cggcgauaag aauagagucc aggccaucau uaacgcucug      600

caagagucug ggcggacaua uaccgccaau gacaugaagg gaaucgaaac auuuaccgag      660

gugcuucgcg cgggcuucua ccugggguac uauaacgaug gacucagcua ccugaaugac      720

agaaacuuuc aggauaaaug cauucccgcc augaucgcua uccagaagaa uccuaacuuc      780

aaacugggca cggccgugca ggacgaaguc auuacauccc ucggcaagcu gaucgggaau      840

gcuagcgcca acgcggaggu ugugaauaac ugugugcccg uccuuaaaca auuucgggag      900

aaucugaacc aguaugcccc ugauuacgug aagggaaccg cuguuaauga acucauuaag      960

ggcaucgagu ucgacuuuuc uggggccgcu uaugaaaaag augugaagac aaugcccugg     1020

uacggaaaaa uugacccuuu caucaacgag cugaaggccc uuggccugua ugggaacauc     1080

accuccgcca ccgaaugggc uagcgacguc ggaauuuacu accucucuaa auucggccug     1140

uauagcacaa aucgcaacga uaucgugcag ucccuggaga aggcgguuga cauguacaag     1200

uauggcaaaa uugccuuugu ggcuauggag agaaucacgu gggauuacga cgggauugga     1260

ucuaauggca agaaagucga ucaugacaag uuccucgaug acgccgaaaa acacuaucug     1320

ccgaagaccu acacauuuga uaacgggacc uucaucaucc gggccggaga caaggugagc     1380

gaggaaaaga uuaagcgccu uuauugggcu uccagagagg ucaaaagcca guuucaucgg     1440

gugguuggca augauaaggc ccuggaagug gggaacgcgg acgacguccu cacaaugaaa     1500

aucuucaauu cucccgagga guacaaguuu aacaccaaua uuaacggagu guccacggau     1560

aauggcggcc uguacaucga accuagaggg acauucuaua ccuacgagcg cacaccccaa     1620

cagagcauuu uuagccuuga ggagcuguuc cggcacgagu auacccauua ccuccaggcu     1680

agauaucugg uugacggacu guggggccaa gggccuuuuu acgagaaaaa ccgccucacc     1740

ugguucgaug aaggaacagc cgaauuuuuc gccggcucca cgcggaccag cggggugcug     1800

cccagaaagu ccauccuugg cuaucuggcu aaggacaaag ucgaucaccg cuacucucuc     1860

aagaaaacac ugaauagcgg auacgacgau uccgacugga uguucuauaa cuacggcuuu     1920

gccguggcuc acuaucugua cgagaaggau augccgaccu ucauuaaaau gaauaaggcc     1980

auccuuaaca cagacgugaa gucuuaugau gaaaucauua aaaagcucag cgacgaugcg     2040

aacaaaaaua ccgaguacca gaaccauauc caggagcugg ccgacaagua ucagggggcu     2100

gggauuccuc ugguuuccga cgauuaccuc aaagaccacg gcuacaagaa ggccagcgaa     2160

gucuauucug agaucuccaa agcugccagc cugacgaaua ccucugugac agcggaaaag     2220

ucccaauacu uuaacaccuu cacacuucgg gggaccuaua cgggagagac aagcaaaggc     2280

gaauuuaagg auugggacga gaugucuaaa aagcuggaug ggacccucga gagccuggcc     2340

aaaaauuccu ggagcggcua caaaacacug accgcuuauu ucaccaacua cagagugaca     2400

ucugacaaua agguccagua ugaugugguu uuucauggag ugcuuacgga caacgccgau     2460

auuuccaaua acaaagcucc caucgccaag gucaccggcc cuagcacagg ggccguggga     2520

cgcaauaucg aguucuccgg caaagacucu aaggaugaag acgggaaaau uguuagcuac     2580

gauugggacu uuggagacgg cgcuaccucc cgggggaaga acucugugca cgcguacaag     2640

aaagccggca cauauaaugu cacccucaag gugacggaug acaaaggagc uacagccacc     2700

gaaucuuuca ccaucgagau uaagaacgaa gauacaacca cacccaucac gaaagagaug     2760

gagcccaaug acgauauuaa ggaagccaac ggcccuaucg uugagggggu gaccgucaag     2820

ggagaccuga acggcuccga ugacgcugau acauuuuacu ucgacgugaa agaagauggg     2880

gacgugacca ucgagcugcc guauucugga agcuccaauu uuacauggcu cgucuacaag     2940

gagggcgacg aucagaacca cauugccagc gggaucgaca aaaauaacuc uaagguuggc     3000

accuucaaau ccacgaaggg aagacauuau guguucauuu acaagcacga uagcgcgucu     3060

aauaucuccu auagccugaa cauuaaaggc cuugggaaug aaaagcugaa agagaaggaa     3120

aacaaugacu cuuccgauaa agcuaccgug auccccaacu uuaauacaac caugcaggga     3180

agccuccugg gcgacgauuc ccgcgacuac uacagcuucg aggucaagga agagggggag     3240

gugaacaucg aacuggauaa gaaagacgag uuuggaguua cauggacccu ucauccugaa     3300

ucuaauauua acgaucggau cacauauggc caaguggacg gcaauaaggu cagcaacaaa     3360

gugaagcuca gacccgggaa auacuaucug cugguuuaca aguauuccgg aucuggcaau     3420

uacgagcucc gggugaacaa gugaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  1856
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt5)

<400>  1856
gggagaaagc uuaccaugaa cuuccugaag aucauucuca auagaggcaa aaccaugaag       60

cggaaaugcc ugagcaagcg ccuuaugcug gccaucacaa uggcuacgau uuuuaccgug      120

aacuccacac uccccaucua cgccgcgguc gacaaaaaua acgcuaccgc cgccguucag      180

aaugagucua agagauauac agugagcuac cugaagaccc uuaacuauua cgaucuggug      240

gaccuccugg ucaaaacaga aauugagaau cugccugauc ucuuccaaua uuccucugac      300

gcuaaggaau uuuacgggaa caaaacccgg augagcuuca ucauggauga gaucggacgc      360

agagccccgc aguauacgga aauugaccac aagggcaucc ccacccuggu ggagguugug      420

cgggcugggu uuuaccuugg auuccauaau aaagagcuga acgaaauuaa uaagcgcucc      480

uuuaaggaga gagucauccc uucuauucuc gccauccaga aaaaccccaa uuucaagcug      540

ggcacagaag ugcaggauaa aauuguuagc gcgaccgggc uucuggccgg aaacgagaca      600

gcuccucccg agguggucaa uaacuuuacc ccuauccucc aagacuguau caagaacauu      660

gaucgguacg cccuggacga ucugaaaucc aaggcucucu ucaaugugcu ggccgcgccg      720

acguaugaca ucacagaaua ccuucgcgcc accaaagaga agcccgaaaa cacaccuugg      780

uauggcaaga uugauggcuu uaucaaugag cugaaaaagc ucgcucugua cgggaaaauu      840

aacgacaaua acagcuggau caucgacaau ggaauuuauc acaucgcucc ccuuggcaag      900

cugcauucua acaauaaaau ugggaucgaa acccucaccg aggugaugaa ggucuacccu      960

uaucugucca ugcagcaccu ucagagcgcc gaucagauua agagacauua cgacucuaaa     1020

gaugccgagg gaaacaagau cccccucgac aaauucaaga aagaaggcaa ggagaaguac     1080

ugcccgaaaa cauauacguu ugaugacggg aagguuauca uuaaagccgg agcucgggug     1140

gaagaggaaa aggugaaacg ccuguacugg gcguccaagg aggucaauag ccaauucuuc     1200

agaguguaug gcaucgauaa gccucuugag gaaggcaacc ccgacgauau ucugaccaug     1260

guuaucuaca auucuccuga ggaauauaaa cucaacuccg ugcuguacgg guaugacaca     1320

aauaacggag gcauguacau ugagcccgaa gggaccuuuu ucacauacga gcgggaggcc     1380

caggaaagca ccuauacgcu ugaggaacug uuucgccacg aguacacaca cuaucuccag     1440

ggaagauacg cuguccccgg ccaguggggg cggaccaagc uguaugauaa cgacagacug     1500

accugguacg aggaaggagg cgccgaacuc uucgccggcu ccacacgcac cucugggauc     1560

cugccucgga aaagcauugu guccaauauc cauaacacaa cgagaaauaa ccgcuauaag     1620

cugagcgaca ccguucacuc uaaauacgga gcuuccuuug aguucuacaa uuaugccugu     1680

auguuuaugg auuacaugua uaacaaggac augggcaucc ugaauaaacu caacgaucug     1740

gcgaagaaua acgacgugga uggguacgac aauuauauuc gggaucugag cucuaacuac     1800

gcucuuaaug acaaguauca agaucauaug caggagagaa ucgacaacua cgaaaaucuc     1860

acagucccgu ucguggccga ugacuaccug guccgccacg ccuauaaaaa ccccaacgag     1920

auuuacagcg agaucuccga aguggcuaag cugaaagaug ccaagucuga gguuaaaaag     1980

agccaguauu uuuccaccuu cacacuccgg ggaagcuaca ccggcggggc uucuaagggc     2040

aaacuggaag accaaaaggc caugaauaaa uuuauugacg auucccuuaa gaaacuggac     2100

acguauagcu ggucuggaua caagacccuc acagcguauu ucaccaacua caagguggau     2160

uccagcaaua gagucacaua cgacgugguu uuucacggcu aucugccuaa cgagggggau     2220

uccaaaaauu cucugcccua cggaaagauc aacggcaccu auaaagggac ggaaaaggag     2280

aaaaucaagu ucagcuccga gggaucuuuc gacccugaug gcaagauugu gagcuacgaa     2340

ugggacuuug gggauggcaa uaaauccaac gaggaaaauc ccgagcauag cuaugacaag     2400

gucggaacau acaccgugaa acuuaaggug acagaugaca aaggcgaauc uuccguuagc     2460

accaccacag ccgagaucaa ggaucucucu gagaacaaac ugccggucau uuauaugcac     2520

gugccuaagu ccggggcucu gaaucagaag guggucuucu acggaaaagg cacguacgac     2580

cccgacggga gcaucgccgg auaucagugg gauuuuggcg acgggucuga uuucagcucc     2640

gaacagaacc cuagccaugu guacaccaag aaaggcgagu auacaguuac ccuccgcgug     2700

auggacucuu ccggacaaau gagcgaaaag acaaugaaaa uuaagaucac cgaucccguc     2760

uacccuaucg gcacggagaa ggagcccaau aacuccaaag aaacagcuuc ugggccgauu     2820

gugccuggaa uccccguuag cggcaccauu gagaauaccu ccgaccagga uuauuuuuac     2880

uucgacguga ucacacccgg ggaagucaag auugauauca acaaacuggg auauggcggg     2940

gccaccuggg ugguuuacga cgagaacaau aacgcggugu cuuacgccac agaugacggc     3000

cagaaucuua gcggaaaguu uaaagcugac aagccuggcc gguauuacau ccaccuguau     3060

auguucaacg gguccuacau gccguauaga auuaauaucg aaggaucugu cggccgcuga     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  1857
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt5)

<400>  1857
gggagaaagc uuaccaugaa gagaaaaugc cugagcaagc ggcucaugcu ggccaucacc       60

auggcuacaa uuuucacggu gaacuccacc cuucccaucu acgccgcggu cgacaaaaau      120

aacgcuacag ccgccguuca gaaugagucu aagcgcuaua ccgugagcua ccugaaaaca      180

cucaacuauu acgaucuggu ggaccuucug gucaagaccg aaauugagaa ucucccugau      240

cuguuucaau auuccucuga cgcuaaggag uucuacggca acaaaacaag aaugagcuuu      300

aucauggaug aaauugggcg gcgcgccccg caguauaccg aaaucgacca caagggaauc      360

cccacgcugg uggagguugu gagagcuggc uucuaccucg gguuucauaa uaaagagcug      420

aacgaaauua auaagcgguc cuucaaagag cgcgucaucc cuucuauucu ugccauccag      480

aagaacccca auuuuaagcu gggaaccgaa gugcaggaua aaauuguuag cgcgacaggc      540

cuccuggccg ggaacgagac cgcuccuccc gaggugguca auaacuucac accuauccuu      600

caagacugua uuaagaauau cgauagauac gcccuggacg aucucaaauc caaggcucug      660

uuuaacgugc uggccgcgcc gaccuaugac aucacggaau accuccgggc cacaaaagag      720

aagcccgaaa acaccccuug guauggaaaa auugauggcu ucaucaauga gcugaagaaa      780

cuugcucugu acggcaagau uaacgacaau aacagcugga ucauugacaa ugggaucuau      840

cacaucgcuc cccucggaaa gcugcauucu aacaauaaaa uuggcaucga aacacuuacc      900

gaggugauga aggucuaccc uuaucugucc augcagcacc uccagagcgc cgaucagauu      960

aaacgccauu acgacucuaa ggaugccgag gggaacaaga ucccccugga caaauuuaag     1020

aaagaaggaa aggagaaaua cugcccgaag accuauacau ucgaugacgg caagguuauu     1080

aucaaagccg gggcuagagu ggaagaggaa aaggugaaac ggcuguacug ggcguccaag     1140

gaggucaaua gccaauuuuu ccgcguguau ggaaucgaua aaccucucga ggaaggcaac     1200

cccgacgaua uucugacgau gguuaucuac aauucuccug aggaauauaa acuuaacucc     1260

gugcuguacg gcuaugacac caauaacggg ggaauguaca uugagcccga aggcacauuc     1320

uuuaccuacg agagagaggc ccaggaaagc acauauaccc ucgaggaacu guuccggcac     1380

gaguacacgc acuaucuuca ggggcgcuac gcuguccccg gacagugggg cagaacaaag     1440

cuguaugaua augaccggcu caccugguac gaggaagggg gagccgagcu guuugccggc     1500

uccaccagaa caucuggcau ccugccucgc aagagcauug uguccaacau ccauaacacc     1560

acacggaaua acagauauaa gcucagcgac acgguucacu cuaaauacgg ggcuuccuuc     1620

gaauuuuaca auuaugccug uauguucaug gauuacaugu auaacaagga caugggcauu     1680

cugaauaaac uuaacgaucu ggcgaagaau aacgacgugg auggauacga caauuauauc     1740

cgcgaucuca gcucuaacua cgcucugaau gacaaauauc aagaucauau gcaggagcgg     1800

aucgacaacu acgaaaaucu gaccgucccg uuuguggccg augacuaccu ugucagacac     1860

gccuauaaga accccaauga gauuuacagc gagaucuccg aaguggcuaa gcucaaagau     1920

gccaagucug agguuaaaaa gagccaguau uucuccacau uuacccugcg cgggagcuac     1980

acaggaggcg cuucuaaagg gaagcuggaa gaccaaaagg ccaugaacaa auucauugac     2040

gauucccuca agaaacugga caccuauagc uggucuggcu acaagacgcu uaccgcguau     2100

uuuacaaacu acaaagugga uuccagcaau cgggucaccu acgacguggu uuuccacgga     2160

uaucugccua acgagggcga uuccaaaaau ucucuccccu acgggaagau caacggaaca     2220

uauaagggca ccgaaaagga gaaaauuaag uuuagcuccg aggggucuuu cgacccugau     2280

ggaaaaaucg ugagcuacga augggacuuc ggcgauggga auaaguccaa cgaggaaaau     2340

cccgagcaua gcuaugacaa ggucggcacg uacacaguga aacugaaggu gaccgaugac     2400

aaaggagaau cuuccguuag cacaaccacc gccgagauca aggaucuguc ugagaacaaa     2460

cuuccgguca uuuauaugca cgugccuaag uccggcgcuc ucaaucagaa aguggucuuu     2520

uacgggaagg gaacauacga ccccgacggc agcaucgccg gguaucagug ggauuucgga     2580

gacggcucug auuuuagcuc cgaacagaac ccuagccaug uguacacgaa gaaaggggag     2640

uauaccguua cacugagagu gauggacucu uccggccaaa ugagcgaaaa gaccaugaaa     2700

auuaagauca cagaucccgu cuacccuauu ggaaccgaga aagagcccaa uaacuccaag     2760

gaaacggcuu cuggcccgau cgugccuggg auccccguua gcggaacaau ugagaauacc     2820

uccgaccagg auuauuucua cuuugacgug aucacccccg gcgaagucaa gauugauauc     2880

aacaaacugg gguauggagg cgccacaugg gugguuuacg acgagaauaa caacgcggug     2940

ucuuacgcca ccgaugacgg gcagaaucuc agcggcaagu ucaaagcuga caagccugga     3000

cgcuauuaca uucaccugua uauguuuaac ggcuccuaca ugccguaucg gaucaauauc     3060

gaagggucug ucggaagaug aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  1858
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt5)

<400>  1858
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuucu guucuccucu       60

gccuacagcg uccagaacga guccaaaaga uauacaguuu cuuaccuuaa gacgcugaau      120

uauuacgacc ucguggaucu gcuugugaaa accgaaauug agaaccugcc cgaccucuuu      180

caauauagcu ccgaugcuaa ggaguucuac ggcaauaaaa cacggauguc uuuuaucaug      240

gacgaaauug ggcgcagagc cccucaguau accgaaaucg aucacaaggg cauuccgaca      300

cuggucgagg ugguucgggc gggauucuac cugggguuuc auaacaagga gcucaaugaa      360

aucaacaaac gcagcuucaa ggagagagug auccccucca uucuggcuau ccagaaaaau      420

ccuaacuuua agcugggaac cgaaguccag gacaaaauug ugagcgccac aggccugcuc      480

gccgggaaug agaccgcucc cccugagguu gugaacaauu ucacgcccau ccugcaagau      540

ugcauuaaga acaucgaccg guacgcccuu gaugaccuga agucuaaagc ucucuuuaau      600

guccuggccg cgccuaccua ugauauuaca gaauaccugc gcgccaccaa ggagaaaccg      660

gaaaacacac ccugguaugg aaagaucgac ggcuucauca augagcucaa aaagcuggcu      720

cuuuacggca aaauuaacga uaacaauucc uggaucauug acaacgggau cuaucacauu      780

gccccucugg gaaagcucca uagcaauaac aagaucggca ucgaaacccu gacggaggug      840

augaaagugu accccuaucu uucuaugcag caccuucagu ccgcugacca gauuaagaga      900

cauuacgaua gcaaagacgc cgaggggaau aagaucccuc ucgauaaauu uaagaaggaa      960

ggaaaagaga aguacugucc caaaacauau accuucgacg auggcaaggu cauuaucaaa     1020

gcgggggccc ggguugaaga ggaaaaggug aagcgccugu acugggcuuc uaaagaggug     1080

aacucccaau ucuuuagagu cuauggaauu gacaagccgc uggaggaagg caauccugau     1140

gacauccuca caauggugau cuacaacagc cccgaggaau auaaacuuaa uuccguucuu     1200

uacggcuaug auaccaacaa ugggggaaug uacauugagc cugaaggcac cuucuuuaca     1260

uacgagcggg aggcccagga aucuacguau acccuggagg aacucuuccg ccacgaguac     1320

acacacuauc ugcaggggag auacgcugug cccggacagu ggggccggac caagcuguau     1380

gacaacgauc gccugacaug guacgaggaa gggggagccg agcucuuugc cggcagcacc     1440

agaacguccg gcauccugcc ccggaaaagc auugucucua auauccauaa cacaaccaga     1500

aauaaccgcu auaagcuguc cgacaccgug cacagcaagu acggggcuuc uuucgaauuu     1560

uacaacuaug cgugcauguu cauggacuac auguauaaua aagauauggg cauucucaac     1620

aagcugaaug accuugccaa aaacaaugau guugacggau acgauaacua uauccgggac     1680

cugagcucca auuacgcucu caacgauaag uaucaagacc auaugcagga gagaauugau     1740

aauuacgaaa accugacagu gccuuuuguc gccgacgauu accuggugcg ccacgccuau     1800

aaaaauccga acgagaucua cucugagauc agcgaagucg cuaaacuuaa ggacgccaag     1860

uccgagguga agaaaagcca guauuucucu accuuuacac uccggggguc cuacacggga     1920

ggcgcgagca aggggaaacu ggaagaucaa aaggcuauga auaaauucau ugacgacucu     1980

cugaagaagc ucgauaccua uuccuggagc ggcuacaaaa cacugaccgc cuauuuuaca     2040

aacuacaagg uugacuccuc uaauagagug accuacgaug ucguguucca cggauaucuu     2100

cccaacgagg gcgacagcaa aaacucccug ccuuacggga agaucaaugg aacguauaaa     2160

ggcaccgaaa aggagaagau uaaauucucu agcgaggggu ccuuugaucc cgacggaaag     2220

aucguuagcu acgaauggga uuucggcgac gggaacaaau cuaaugagga aaacccugag     2280

cauuccuaug auaagguggg cacauacacc gucaaacuca aggugacaga cgauaaggga     2340

gaaagcucug uguccaccac gacagccgag auuaaagacc ugagcgagaa uaagcugccc     2400

guuaucuaua ugcacguccc gaaaucuggc gcucuuaacc agaagguggu guuuuacggg     2460

aaaggaaccu acgauccuga cggcagcauc gccggguauc agugggacuu cggagauggc     2520

uccgacuuua gcucugaaca gaaucccucc caugucuaca caaagaaagg ggaguauacc     2580

gugacccucc gcguuaugga uagcuccggc caaaugucug aaaagacaau gaagauuaaa     2640

aucacggacc cuguguaccc cauuggaacc gagaaggagc cuaacaauag caaagaaaca     2700

gcuuccggcc ccaucguccc ggggauuccu gugucuggaa ccaucgagaa cacaagcgau     2760

caggacuauu ucuacuuuga uguuaucacc cccggcgaag ugaagauuga caucaauaaa     2820

cugggguaug gaggcgccac gugggucgug uacgaugaga acaauaacgc gguuuccuac     2880

gccacagacg augggcagaa ucugucuggc aaguucaagg cugacaaacc cggacgguau     2940

uacauucacc ucuauauguu uaacggcagc uacaugccuu auagaaucaa cauugaaggg     3000

uccgugggac gcugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1859
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt5)

<400>  1859
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuucu guucuccucu       60

gccuacagca ugaaaagaaa gugccuuucc aaacggcuga ugcucgcuau uacaauggcc      120

acgaucuuua ccgucaacuc uacacugccc auuuaugcgg cuguugacaa gaauaacgcc      180

accgccgcuc gcagacggcg caaaagagug cagaaugaga gcaagcggua cacagugucc      240

uaucuuaaga cccugaacua cuaugaucuc gucgaccugc uggugaaaac agaaaucgag      300

aaucucccug aucuguucca auacucuagc gacgccaagg aauuuuaugg caacaaaacc      360

cgcauguccu ucauuaugga ugagaucggg agacgggcuc cgcaguacac ggaaaucgac      420

cacaagggca uucccacccu uguugaggug guccgcgccg gauuuuaccu gggguuccau      480

aauaaagagc ucaacgaaau caauaagaga uccuuuaagg agcgggugau uccuucuauc      540

cuggcgauuc agaaaaaccc caauuucaaa cuuggaacag aaguucagga uaagaucgug      600

uccgccaccg gccugcucgc ugggaacgag acagccccuc ccgaggucgu gaauaacuuu      660

accccuauuc ugcaagacug uaucaagaau aucgaucgcu augcucugga cgaucucaaa      720

agcaaggccc uguucaacgu gcuugcggcc ccgacguacg acauuacaga auaucugaga      780

gcuaccaaag agaagcccga aaacacaccu ugguacggaa agaucgaugg cuuuauuaau      840

gagcucaaaa agcuggcccu uuauggcaaa aucaacgaca auaacucuug gauuaucgac      900

aaugggaucu accacauugc uccccuggga aagcuccauu ccaacaauaa aaucggcauu      960

gaaacccuga ccgaggucau gaagguuuau ccuuaccuga gcaugcagca ccuccagucu     1020

gccgaucaga ucaagcggca uuacgacucc aaagaugccg aggggaacaa gauuccccug     1080

gacaaauuca agaaagaagg aaaggagaag uauugcccga aaacauacac guucgaugac     1140

ggcaagguga ucaucaaagc uggggcgcgc guggaagagg aaaaggucaa aagacuuuau     1200

ugggccagca aggaggugaa uagccaauuu uuccggguuu acggaauuga uaagccucug     1260

gaggaaggca accccgacga uauccucacc auggugauuu auaauucucc ugaggaauac     1320

aaacugaaca gcguccuuua uggcuacgac acaaauaacg ggggaaugua caucgagccc     1380

gaaggcaccu uuuucacaua ugagagagag gcucaggaau ccaccuacac gcuggaggaa     1440

cucuuucgcc acgaguauac acacuaccug caggggcggu augccgugcc cggacagugg     1500

ggcagaacca agcuguacga uaaugaccgc cucaccuggu augaggaagg gggagccgag     1560

cuguucgcug gcagcacacg gaccucuggc auucuuccua gaaaauccau cguuagcaac     1620

auucauaaca caacgcgcaa uaaccgguac aagcugucug acaccgugca cagcaaauac     1680

ggggccuccu uugaguucua uaauuacgcg uguauguuua uggauuauau guacaacaag     1740

gacaugggaa uccucaauaa acugaacgau cuggcuaaga auaacgacgu cgauggcuau     1800

gacaauuaca ucagagaucu uucuagcaac uaugcccuca augacaagua ccaagaucau     1860

augcaggaac gcauugacaa cuacgaaaau cugacagugc cguucgucgc cgaugacuau     1920

cuggugcggc acgcuuacaa aaaccccaau gagaucuauu ccgagauuag cgaaguugcc     1980

aagcucaaag augcuaaguc ugaggugaaa aagucccagu acuuuagcac cuucacacug     2040

agagggucuu auaccggagg cgccuccaag gggaaacuug aagaccaaaa ggcgaugaac     2100

aaauuuaucg acgauagccu gaagaaacuc gacacguacu ccuggucugg cuauaagacc     2160

cugacagccu acuucaccaa cuacaagguc gauagcucca aucgcgugac auaugacguu     2220

guguuccacg gauaccugcc uaacgagggc gauucuaaaa auagccuucc cuaugggaag     2280

auuaacggaa ccuacaaagg cacggaaaag gagaaaauca aguuuuccag cgaggggucu     2340

uucgacccug auggaaagau cgucuccuau gaaugggacu uuggcgaugg gaauaaaagc     2400

aacgaggaaa aucccgagca uucuuacgac aaggugggca cauauaccgu gaaacucaag     2460

guuacagaug acaaaggaga auccagcguc ucuaccacca cagcugagau uaaggaucug     2520

agcgagaaca aacugccggu gaucuacaug cacgugccua aguccggcgc ccucaaucag     2580

aaggucgugu ucuacgggaa aggaacguau gaccccgacg gcagcauugc uggguaccag     2640

ugggauuuug gagacggcuc ugauuucucc agcgaacaga acccuuccca uguuuauacc     2700

aagaaagggg aguacacagu gacccugcgg gucauggacu cuagcggcca aauguccgaa     2760

aagacaauga aaaucaagau uaccgauccc guguauccua ucggaacgga gaaggagccc     2820

aauaacucua aagaaacagc cagcggcccg aucguuccug ggauucccgu guccggaacc     2880

aucgagaaua ccucugacca ggauuacuuu uauuucgacg ucauuacacc cggcgaagug     2940

aagaucgaua uuaacaaacu uggguacgga ggcgcgaccu ggguugugua cgacgagaau     3000

aacaacgccg ucagcuaugc uacagaugac gggcagaauc uguccggcaa guuuaaagcc     3060

gacaagccug gaagauacua uauccaccuc uacauguuca acggcagcua uaugccguac     3120

cggaucaaua uugaaggguc ugugggacgc ugaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  1860
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt5)

<400>  1860
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggcugccuuu       60

gcgaugcccc uuccuccgca ccccggacau ccuggcuaca uuaacuucag cuaugaggug      120

cugacacccc ucaaguggua ccaguccauc agaccucccu auccuucuua cggguaugaa      180

ccgaugggag gcuggcugca ccaucaaauu auccccgucc uuagccagca gcacccuccc      240

acgcauaccc ugcagccuca ccaccauauu cccguugugc cggcucaaca gccugugauc      300

ccccagcagc cuaugaugcc cguccccggg caacacucca ugacaccuau ccagcaucac      360

cagccgaauc ugcccccucc cgcccagcaa ccuuaccagc cccagccggu gcaaccucag      420

ccccaccagc cuaugcagcc ccaaccuccc guucauccga ugcagccucu cccuccccag      480

cccccgcugc ccccuauguu ucccaugcag ccucugcccc cuaugcuccc cgaccuuacc      540

cuggaggccu ggccgucuac agauaaaacc aagcgggaag agguggacug aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  1861
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt5)

<400>  1861
gggagaaagc uuaccaugcc ccugccuccg caccccggcc auccugggua caucaacuuc       60

agcuaugagg ugcucacccc ucugaagugg uaccagucca uuagaccucc cuaucccucu      120

uacggauaug aaccgauggg cgggugguga ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  1862
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt5)

<400>  1862
gggagaaagc uuaccaugcc ccugccuccg caccccggcc auccugggua caucaacuuc       60

agcuaugagg ugcucacacc ccugaagugg uaccagucca uuagaccucc cccuaugcuu      120

ccggaccuga cccucgaagc cuggcccucu acggauaaaa ccaagcggga ggaagucgac      180

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  1863
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt5)

<400>  1863
gggagaaagc uuaccauggc cgugauggcu cccagaaccc ugguccuccu gcuuagcggc       60

gcccuggcgc ucacacagac gugggcuaug ccucugccgc cccacccugg gcaucccgga      120

uacaucaacu ucuccuauga gguucuuacc ccucugaagu gguaccaauc uauucggccc      180

ccuuauccga gcuacggcua ugaacccaug ggaggguggu gaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  1864
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt5)

<400>  1864
gggagaaagc uuaccauggc cgugauggcu cccagaaccc ugguccuccu gcuuagcggc       60

gcccuggcgc ucacacagac gugggcuaug ccucugccgc cccacccugg gcaucccgga      120

uacaucaacu ucuccuauga gguucuuacc ccucugaagu gguaccaauc uauucggccc      180

ccuccgaugc uccccgaccu gacacuggaa gccuggccua gcaccgauaa aacaaagcgc      240

gaggaagugg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  1865
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt5)

<400>  1865
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccucguggg ggcugccuuu       60

gcgaugcccc ugccuccgca ccccggacau ccuggcuaca uuaacuucag cuaugagguc      120

cuuacacccc ugaaguggua ccaguccaug aucagaccuc ccuauucuag cuacggguau      180

gaaccuaugg gaggcuggcu ccaccaucaa auuaucccgg uuguguccca gcagcacccc      240

cugacgcaua cccuucaguc ucaccaccau auuccugugg uccccgcuca acagccucgg      300

gugcgccagc aggcccugau gcccguuccg gggcaacaga gcaugacacc uacccagcac      360

caucagccca aucucccucu gcccgcccaa cagcccuuuc agccucaacc ggugcagccc      420

cagccucacc agcccaugca accucagccc ccgguccagc cuaugcagcc ccugcucccu      480

caacccccuc ugcccccgau guucccucuu agaccccugc ccccuauccu cccggaccug      540

caccuugagg cuuggcccgc cacagauaaa accaagcagg aagaggugga cugaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  1866
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt5)

<400>  1866
gggagaaagc uuaccaugcc ccugccuccg caccccggcc auccugggua caucaacuuc       60

agcuaugagg ugcucacccc ucugaagugg uaccagucca ugauuagacc ucccuauucu      120

agcuacggau augaacccau gggcgggugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1867
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt5)

<400>  1867
gggagaaagc uuaccaugcc ccugccuccg caccccggcc auccugggua caucaacuuc       60

agcuaugagg ugcucacacc ccugaagugg uaccagucca ugauuagacc ucccccuauc      120

cuuccggacc ugcaccucga agccuggccc gcuaccgaua aaacgaagca agaggaaguc      180

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1868
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt5)

<400>  1868
gggagaaagc uuaccauggc cgugauggcu cccagaaccc ugguccuccu gcuuagcggc       60

gcccuggcgc ucacacagac gugggcuaug ccucugccgc cccacccugg gcaucccgga      120

uacaucaacu ucuccuauga gguucuuacc ccucugaagu gguaccaauc uaugauucgg      180

cccccuuaua gcuccuacgg cuaugaaccg augggagggu ggugaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1869
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt5)

<400>  1869
gggagaaagc uuaccauggc cgugauggcu cccagaaccc ugguccuccu gcuuagcggc       60

gcccuggcgc ucacacagac gugggcuaug ccucugccgc cccacccugg gcaucccgga      120

uacaucaacu ucuccuauga gguucuuacc ccucugaagu gguaccaauc uaugauucgg      180

cccccuccga uccuccccga ccugcaccug gaagccuggc cugccacaga uaaaaccaag      240

caggaggaag uggacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1870
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt5)

<400>  1870
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggcugccuuu       60

agcaugcccc uuccuccgca ccccggacau ccuggcuaca uuaacuucuc cuaugaggug      120

cugacacccc ucaaguggua ccagaauaug aucagacacc cuuauacguc uuacggguau      180

gaacccaugg gaggcuggcu gcaucaccaa auuaucccug ucguuagcca gcagaccccg      240

cagucccaug cgcuucaacc ccaccaccau auuccuaugg ugcccgcuca gcagccuggg      300

aucccccagc aaccgaugau gccucugccc ggacagcacu cuaugacacc uacccagcau      360

caccagccca accucccccu gccugcccaa cagccguuuc agccccaacc ugugcagccc      420

cagccucacc agccccugca accgcagagc ccuaugcauc ccauccagcc ucuccugccc      480

cagccucccc uuccgccuau guucuccaug caaucucugc uccccgaccu gccccuugag      540

gccuggccug cuacagauaa aaccaagcgg gaagaggucg acugaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1871
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt5)

<400>  1871
gggagaaagc uuaccaugcc ccugccuccg caccccggcc auccugggua caucaacuuc       60

agcuaugagg ugcucacacc ccugaagugg uaccagaaua ugauuagaca cccuuauacc      120

uccuacggau augaacccau gggcgggugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1872
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt5)

<400>  1872
gggagaaagc uuaccaugcc ccugccuccg caccccggcc auccugggua caucaacuuc       60

agcuaugagg ugcucacacc ccugaagugg uaccagaaua ugauuagaca cccuucccuu      120

cugcccgacc ucccucugga agccuggccg gcuaccgaua aaacgaagcg ggaggaaguc      180

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1873
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt5)

<400>  1873
gggagaaagc uuaccauggc cgugauggcu cccagaaccc ugguccuccu gcuuagcggc       60

gcccuggcgc ucacacagac gugggcuaug ccucugccgc cccacccugg gcaucccgga      120

uacaucaacu ucuccuauga gguucuuacc ccucugaagu gguaccaaaa uaugauucgg      180

caccccuaua caucuuacgg cuaugaaccu augggagggu ggugaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1874
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt5)

<400>  1874
gggagaaagc uuaccauggc cgugauggcu cccagaaccc ugguccuccu gcuuagcggc       60

gcccuggcgc ucacacagac gugggcuaug ccucugccgc cccacccugg gcaucccgga      120

uacaucaacu ucuccuauga gguucuuacc ccucugaagu gguaccaaaa uaugauucgg      180

caccccucuc uccugccuga ccugccgcuc gaagccuggc ccgccacaga uaaaaccaag      240

cgcgaggaag uggacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1875
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt5)

<400>  1875
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggcugccuuu       60

agcaugcccc uuccuccgca ccccggacau ccuggcuaca uuaacuucuc cuauaucaga      120

caccccuaca caucuuaugg guacgagccu augggaggcu ggcugcauca ccagauuauc      180

cccgugguca gccaacagac gccucagucc caugcgcucc agccgcacca ccauauuccc      240

augguuccug cucaacagcc cgggaucccu cagcagccca ugaugccgcu gccuggacaa      300

cacucuauga cccccacaca gcaucaccag ccuaaucuuc cccugcccgc ccagcaaccu      360

uuucagccgc agcccgugca accucagccc caccagccuc uccagcccca aagcccgaug      420

cauccuaucc agccccugcu gccucagccc ccucugcccc cgauguucuc caugcagucu      480

cuccuuccug accugccccu cgaagccugg cccgcuaccg auaagacaaa acgggaggaa      540

guggacugag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  1876
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt5)

<400>  1876
gggagaaagc uuaccauggg caccuggauc uucuuugccu gccugcucgg ggcuagccug       60

gccaugcccc uuccuccgca ccccggacau ccuggcuaca uuaacuucuc cuaugaggug      120

cugacacccc ucaaguggua ccagaauaug aucagacacc cuuauacguc uuacggguau      180

gaacccaugg gaggcuggcu gcaucaccaa auuaucccug ucguuagcca gcagaccccg      240

cagucccaug cgcuucaacc ccaccaccau auuccuaugg ugcccgcuca gcagccuggg      300

aucccccagc aaccgaugau gccucugccc ggacagcacu cuaugacacc uacccagcau      360

caccagccca accucccccu gccugcccaa cagccguuuc agccccaacc ugugcagccc      420

cagccucacc agccccugca accgcagagc ccuaugcauc ccauccagcc ucuccugccc      480

cagccucccc uuccgccuau guucuccaug caaucucugc uccccgaccu gccccuugag      540

gccuggccug cuacagauaa aaccaagcgg gaagaggucg acugaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1877
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt5)

<400>  1877
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggcugccuuu       60

agcaugcccc uuccuccgca ccccggacau ccuggcuaca uuaacuucuc cuaugaggug      120

cugacacccc ucaaguggua ccagaauaug aucagacacc cuucucugcu ucccgaccug      180

ccucucgaag cguggccggc uacggauaaa accaagcggg aggaagucga cugaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  1878
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt5)

<400>  1878
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggcugccuuu       60

agcaugcccc uuccuccgca ccccggacau ccuggcuaca uuaacuucuc cuaugaggac      120

cuguaccucg aagcgaucag aauugaucgg acagcuuuug ugcugacgcc ccuuaagugg      180

uaucagaaua ugauccgcca cccuuacacc ucuuaugggu acgagcccau gggaggcugg      240

cugcaucacc aaauuauccc ugucguuagc cagcagacac cgcaguccca ugcccuccaa      300

ccccaccacc auaucccuau ggugcccgcc cagcagccug ggauucccca gcaaccgaug      360

augccucugc ccggacagca cucuaugacc ccuacacagc aucaccagcc caaccugccc      420

cucccugcuc aacagccguu ccagccccaa ccugugcagc cccagccuca ccagccccug      480

caaccgcaga gcccuaugca ucccauccag ccucuucugc cccagccucc ccucccgccu      540

auguuuucca ugcaaucucu gcuucccgac cugccccucg aagccuggcc ugcuaccgau      600

aaaacaaaga gagaggaagu cgacugagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  1879
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt5)

<400>  1879
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggcugccuuu       60

agcaugcccc uuccuccgca ccccggacau ccuggcuaca uuaacuucuc cuaugaggug      120

cugacacccc ucaaguggua ccagaauaug aucagacacc cuacgcccca aucucaugcg      180

cugcagccuc accaucacau uccgaugguc cccgcucagc agccugggau cccccaacag      240

ccuaugaugc cccuuccggg acagcacagc augaccccua cacagcauca ccaacccaac      300

cugccucucc ccgcccagca gcccuuucag ccucaaccgg uucagcccca gccucaucaa      360

ccccugcagc cucagucccc caugcacccg auucagccuc ugcuccccca accuccccug      420

ccucccaugu ucucuaugca gagccuucug ccggaccucc cucuggaagc cuggcccgcu      480

accgauaaaa caaagcggga ggaaguggac ugaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  1880
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt5)

<400>  1880
gggagaaagc uuaccaugcc ccugccuccg caccccggcc auccugggua caucaacuuc       60

agcuaugagg ugcucacacc ccugaagugg uaccagaaua ugauuagaca cccuuauacc      120

uccuacggau augaacccau gggcgggugg cuucaucacc aaaucauucc ugucguuucu      180

cagcagacgc cgcagagcca ugcccugcaa ccccaccacc auaucccuau ggugcccgcu      240

cagcagccug gcauucccca gcaaccgaug augccucucc ccggacagca cuccaugacc      300

ccuacacagc aucaccagcc caaccugccc cuuccugccc aacagccguu ucagccccaa      360

ccugugcagc cccagccuca ccagccccug caaccgcagu cuccuaugca ucccauccag      420

ccucuccugc cccagccucc ccugccgccu auguucagca ugcaaucccu ccugcccgac      480

cuuccccugg aggcguggcc ugcuaccgau aaaacaaagc gggaagaggu cgacugagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  1881
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt5)

<400>  1881
gggagaaagc uuaccaugcc cggcguggcc agacugccuc uccugcuugg gcugcuccug       60

cuuccgcggc ccggacgccc ucuggaccuc gcugauuaca ccuaugaccu ggccgaggaa      120

gaugacagcg agccccugaa cuacaaggau ccuugcaaag cggcugccuu ccucggcgac      180

aucgcccugg augaagagga ccuuagagcu uuucaggucc aacaggccgu ugaucugcgg      240

cgccacacag cuagaaaguc cucuauuaaa gccgcggugc ccgggaauac gagcaccccu      300

uccugucagu cuacaaacgg acagccgcaa cggggcgccu gcgggcgcug gagaggacgg      360

agccgcucca gacgggcugc caccucucgc cccgaaagag uguggccuga cggcgucauc      420

cccuucguga uuggcgggaa uuuuacagga agccagcggg cuguuuuccg ccaggccaug      480

agacauuggg agaagcacac cugugugaca uuucucgagc ggaccgauga agacuccuau      540

aucgucuuca cguacagacc uugcggcugu ugcagcuaug uggggcgccg gggaggcggg      600

ccccaggcga uuucuaucgg aaagaacugu gauaaguuug gcaucguugu gcaugagcug      660

ggccacgucg ugggguucug gcaugaacac accagaccgg accgcgaccg gcacgugucc      720

auugucagag agaauaucca accuggacag gaguacaacu uucuuaagau ggaaccccag      780

gagguugaaa gccugggcga gacauaugau uucgacucua uuaugcauua cgcccgcaau      840

accuuuuccc gggggaucuu ccucgauaca auugugccua aauacgaagu gaacggaguc      900

aagccuccca ucggccagag aacccgccug agcaaagggg acauugcuca agcccggaag      960

cuguauaaau gccccgcuug uggagagacg cuccaggauu cuacaggcaa uuuuuccagc     1020

ccggaguacc ccaacggcua uuccgcccac augcauugcg uguggagaau cucuguuacc     1080

ccuggggaaa agaucauucu gaauuucaca agccuugacc uguaccgcuc ccggcucugu     1140

ugguaugauu acguggaggu cagagacgga uucuggcgga aggcuccccu gcgcggcaga     1200

uuuugcggga gcaaacuucc ugaacccauc gugucuaccg auucccggcu guggguugag     1260

uucagaagcu cuagcaacug ggugggaaag ggcuuuuucg ccgucuauga agcgauuugc     1320

gggggcgacg ugaaaaagga uuacggacac auccaguccc cgaauuaccc ugacgacuau     1380

cgccccucua aagucuguau uuggcggauc caagugagcg agggcuuuca cguugggcuc     1440

accuuccagu ccuuugagau cgaaagacau gauagcugcg ccuacgacua ucuggaggug     1500

cgcgauggac acucugaauc cagcacacug auuggcagau acugugggua ugagaagccu     1560

gacgauauca aaucuacguc cagccggcuc uggcugaagu ucgucuccga cggaucuauu     1620

aacaaggcug gcuuugccgu gaauuucuuu aaagaaguug augagugcag ccgccccaac     1680

agagggggcu gugagcagcg gugccuuaac acccugggau ccuacaagug uucuugcgac     1740

ccuggcuaug aacucgcccc cgauaaacgc agaugugagg cugccugcgg gggauuccug     1800

acaaaacuua auggcagcau caccuccccg ggguggccua aagaauaccc ucccaacaag     1860

aauuguauuu ggcagcuggu ggcgcccaca caauaccgga ucagccucca guuugacuuc     1920

uucgagaccg agggaaacga ugucugcaag uaugacuuug uggaagugcg cucuggccug     1980

acggcugauu ccaaacugca ugggaaguuc ugcggcagcg agaaaccgga aguuaucaca     2040

ucucaguaca auaacaugag agucgaguuu aaguccgaca auaccgugag caaaaaggga     2100

uucaaggccc acuuuuucuc ugacaaagau gaauguagca aggacaacgg cgggugccag     2160

caagauugug ugaauaccuu uggauccuau gagugccagu gucggagcgg cuucguccuc     2220

caugacaaca aacacgauug caaggaggcc gggugugacc acaaagugac aucuaccucc     2280

ggaacaauua cgagccccaa uuggccugau aaguaccccu ccaagaaaga augcaccugg     2340

gcuaucucua gcacaccugg ccaucgcguu aagcugaccu uuauggagau ggacauugaa     2400

ucccagcccg agugugccua ugaucaccuu gaaguguucg acgggagaga ugcuaaagcc     2460

ccuguccugg gccgguuuug cggaucuaag aaacccgagc cggugcucgc gacaggcagc     2520

agaauguucc ugcgcuuuua cuccgacaac ucuguucagc ggaagggguu ccaagccagc     2580

caugcuaccg aguguggagg ccaggugaga gccgauguca aaacgaagga ccuguauucc     2640

cacgcucagu ucggggacaa uaacuacccu ggaggcgugg auugcgaaug gguuaucgug     2700

gccgaggaag gcuacggggu cgagcuugug uuucagaccu ucgaagugga ggaggaaaca     2760

gacugcggau augauuacau ggagcucuuu gacggcuaug auagcaccgc gccccgccug     2820

gggcgguacu guggaucugg cccucccgaa gaggucuauu ccgccgggga cagcguucug     2880

gugaaguucc acucugauga cacaauuacc aaaaagggau uucaucucag auacacgucc     2940

acaaaauucc aagauacccu gcacagccgc aagugaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  1882
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt5)

<400>  1882
gggagaaagc uuaccauggu ggccggcacc agaugccugc ucgcucugcu ucugccccag       60

guccuccuug ggggagccgc gggccugguu ccugagcugg ggcggcgcaa guucgcugcc      120

gccagcuccg gaagaccguc uagccaaccc uccgacgaag ugcucucuga guuugaacug      180

cggcugcuca gcauguucgg ccugaaacag cgcccuacac ccuccagaga ugcugugguc      240

ccucccuaca ugcuugaccu guaucggcgc cacucugggc agccuggaag cccggccccc      300

gaucauagac ucgagcgggc ugccucccgc gcgaacacgg ugagaucuuu ucaccaugaa      360

gagucucugg aggaacuucc ugagaccucc ggcaagacaa cccggcgcuu cuuuuucaau      420

cugagcucua uccccacaga agaguuuauu accuccgccg agcuccaggu uuucagagaa      480

caaaugcagg acgcucuggg caacaauagc ucuuuucacc aucggaucaa cauuuacgag      540

aucauuaaac cugccacagc uaauuccaag uuccccguga cccgccugcu cgauacgaga      600

cuggucaacc agaaugccag ccggugggaa uccuuugacg ugaccccggc gguuaugaga      660

uggacagccc aggggcacgc uaaccacgga uucguggucg agguggccca ucuugaagag      720

aaacaaggcg ugucuaagcg ccacguccgg aucagcagau cccugcauca ggaugagcac      780

agcuggucuc agauccgccc ucuccugguu accuuugggc acgacggaaa gggccauccc      840

cuucacaaac gggaaaagag acaggcuaaa cauaagcaac gcaaacggcu gaaguccagc      900

uguaagagac acccucucua uguggauuuc ucugacgugg gguggaauga uuggauuguc      960

gccccucccg gauaccaugc cuucuauugc cacggcgagu gucccuuucc gcuggcugac     1020

caccugaaca gcacaaauca ugcgaucgug cagacccucg uuaacuccgu gaauagcaaa     1080

auucccaagg ccugcugugu cccuacggaa cugagcgcua ucuccaugcu uuaccuggau     1140

gagaacgaaa aagugguucu caagaauuau caggacaugg uggucgaggg cugcgggugu     1200

cgcugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  1883
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt5)

<400>  1883
gggagaaagc uuaccaugau ccccggcaac agaaugcuga uggugguccu ccugugccag       60

guucuucucg ggggagccag ccacgcuucc cugauuccug agaccggcaa gaaaaaggug      120

gccgaaaucc aagggcaugc gggaggccgg cgcucugggc agagccacga gcugcuuaga      180

gacuucgaag cuacacugcu ccagauguuu ggacugcggc gcagaccgca gcccuccaaa      240

ucugccguga uuccugauua caugcgggac cuguaucgcc uccaaagcgg cgaggaagag      300

gaggaacaga uccauuccac gggccuggag uaccccgaaa gaccugccuc ucgggcuaau      360

accguccgca gcuuccacca ugaggagcac cuugaaaaca uucccgggac auccgagaau      420

agcgccuuua gauuccuguu uaaccucucu uccaucccug aaaaugaggu gaucagcucu      480

gcugaacugc ggcuuuuccg cgagcagguu gaucagggac cggacuggga gagaggcuuu      540

caccggauua acaucuauga agugaugaag cccccugccg aggucgugcc cgggcaucug      600

auuacccgcc uccuggauac aagacugguu caccauaaug ugacccggug ggaaacauuc      660

gacgucuccc cugcggugcu cagauggacc cgcgagaaac aacccaacua cggacuggcc      720

aucgaaguga cgcaccuuca ccagacccgg acacaucagg gccagcacgu cagaauuagc      780

cgcucucugc cgcaaggguc cggaaauugg gcucagcucc ggccucugcu uguuaccuuu      840

ggccaugaug gcagagggca cgcccugaca cgccggagac gcgcuaagcg gagccccaag      900

caucacuccc agagagcccg caaaaagaac aaaaauuguc ggagacacuc ucucuaugug      960

gacuucagcg augugggaug gaacgacugg aucgucgcgc cucccggcua ccaagccuuu     1020

uauugccaug gggauugucc cuucccucug gcugaccacc ucaauuccac caaccaugcc     1080

auugugcaga cgcugguuaa uagcgugaac ucuuccaucc cgaaggcuug cugugucccc     1140

acagagcuga gcgccaucuc uaugcuuuac cuggaugagu acgacaaagu gguucucaag     1200

aacuaucagg aaaugguggu cgagggaugc ggcugucggu gaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  1884
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt5)

<400>  1884
gggagaaagc uuaccaugcc cggccugggg agacgggccc aguggcucug cugguggugg       60

ggacugcuuu guagcugcug uggcccuccg ccccugcgcc cuccccuccc ugcugccgcg      120

gcugccgccg cugggggaca acugcuuggc gacgggggau cccccggcag aaccgagcag      180

ccuccgcccu cuccucagag cuccucuggc uuccuguacc ggcgccucaa gacacaggag      240

aaaagagaaa ugcaaaagga aauccugagc gugcuggggc ucccccaccg gccucgcccc      300

cugcauggac uucagcagcc gcagccuccc gcccugagac aacaggagga acagcagcaa      360

cagcagcaac ucccucgggg cgagcccccu cccgggcgcc ugaaauccgc uccgcuuuuu      420

augcuggauc ucuauaacgc ccugucugcg gacaaugaug aggacggagc cagcgaaggc      480

gagagacagc aguccuggcc ccacgaagcu gccuccucuu cccagcggcg ccaaccuccc      540

ccuggggcug cccauccccu gaacagaaag agccuccugg cgccgggauc uggcuccggc      600

ggggccagcc cucuuacguc ugcucaggau uccgccuucc ugaaugacgc ugauaugguc      660

augagcuuug uuaaccucgu ggaguacgac aaagaguuca gcccccggca gcgccaccau      720

aaggaauuua aguucaaucu gucucagauu ccugagggag aaguggucac cgccgccgag      780

uuuagaaucu auaaagauug cgugaugggc agcuucaaga accaaacauu ucuuauuucc      840

aucuaccagg uucugcagga acaccagcac cgggacagcg aucucuuccu gcuggacacc      900

agaguggucu gggcuucuga ggaggggugg cucgaauuug auauuacagc gaccuccaau      960

cugugggugg uuacacccca acauaacaug ggacuucagc ugagcguggu cacccgcgac     1020

ggcgugcacg ugcauccucg ggccgcuggg cucgucggaa gagacggccc cuaugauaaa     1080

cagccguuca ugguugccuu uuucaaggug ucugaggugc acguccgcac gacccggagc     1140

gccuccucua gacgccggca gcaaagcaga aaucgcucca cacagagcca ggacguggcu     1200

cggguuucuu ccgccagcga uuacaacucu uccgaacuga aaaccgcgug uagaaagcac     1260

gagcuuuaug ugagcuucca agaccugggc uggcaggauu ggaucaucgc uccuaagggg     1320

uacgccgcca auuacugcga cggagaaugu uccuuucccc ucaacgcuca uaugaaugcc     1380

acaaaccacg cuauugucca gacccuggug caucugauga aucccgagua uguuccuaaa     1440

ccgugcugug cccccacgaa gcucaacgcg aucucugugc uguacuucga ugacaacagc     1500

aaugucauuc uuaaaaagua ucgcaacaug gugguccggg ccugcggcug ucacugagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  1885
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt5)

<400>  1885
gggagaaagc uuaccaugca cgugagaagc cugcgggccg cugcucccca uuccuucguc       60

gcgcucuggg cuccucuguu ucuucugcgc ucugcccucg ccgacuucag ccuggauaac      120

gagguucacu ccucuuuuau ccauagacgg cuucgcagcc aggaaagacg ggagaugcaa      180

cgcgaaauuc uguccauccu cggccugccg cacagacccc ggccucaucu gcaggggaag      240

cacaauucug cucccauguu caugcucgac cuguacaacg ccauggcugu ggaggaagga      300

ggcgggccug gaggccaggg guuuagcuau cccuacaaag ccguguucuc cacccaggga      360

ccuccgcuug cgagccugca agauucucac uuucucacag acgccgauau ggucaugucc      420

uucgugaauc ugguugagca ugacaaggag uuuuuccacc cccgcuauca ucacagagaa      480

uuucgguucg aucuuagcaa aauuccugag ggcgaagcug ugacggccgc ugaguuucgc      540

aucuacaagg acuauauuag agagcgguuc gauaacgaaa ccuuccgcau cucugucuac      600

caggugcugc aggagcaccu cggcagagaa uccgaccugu uucugcucga uagccggaca      660

cugugggccu cugaggaagg guggcuuguu uucgacauca ccgcgacauc caaucauugg      720

guggucaacc ccagacacaa ucugggacuc cagcugagcg uggagacccu ugauggccaa      780

uccauuaacc cuaaacuggc cgggcucauc ggacgccaug gcccccagaa uaagcagccg      840

uuuauggugg cuuucuuuaa ggccacagag guccacuucc ggucuauuag aagcaccggg      900

uccaaacagc gcagccaaaa ccggucuaag acgccuaaaa aucaggaagc ucugagaaug      960

gccaacguug ccgaaaauuc cagcucugac cagcgccaag ccugcaagaa acaugagcug     1020

uaugugagcu uucgggaccu cggauggcag gauuggauca uugcgcccga gggcuacgcc     1080

gcuuacuauu gugaaggcga gugcgccuuc ccucugaacu ccuacaugaa ugccaccaac     1140

cacgcuaucg ugcagacacu uguccacuuu auuaaccccg agaccgugcc caagccuugu     1200

ugcgccccga cacagcugaa ugcgaucucu guucucuauu ucgacgauag cuccaacgug     1260

auccugaaga aauacagaaa uauggucgug cgcgcuugug ggugccauug aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  1886
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt5)

<400>  1886
gggagaaagc uuaccaugaa ggccagcgcu gcccugcucu gccugcuucu gaccgcggcu       60

gccuucucuc cccagggccu cgcccaaccu guggggauca acacauccac gaccuguugc      120

uacagauuua uuaauaaaaa gaucccgaaa cagcggcugg agagcuaucg cagaacaacc      180

uccucucacu guccccggga agcugucauu uucaagacaa aacuugacaa ggagaucugc      240

gccgauccua cccagaagug gguucaggac uuuaugaaac aucuggauaa gaaaacacaa      300

acccccaagc ucugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  1887
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt5)

<400>  1887
gggagaaagc uuaccaugcu gcucacccug aucauucuuc ugcccguggu cagcaaguuc       60

uccuuuguuu cucucagcgc cccucagcac ugguccugcc cggagggcac acuggcuggg      120

aacggaaauu cuacgugugu gggccccgcc ccuuuccuua ucuuuagcca ugggaacucc      180

auuuucagaa ucgacaccga aggaacaaau uacgagcaac ugguggucga ugcgggcgug      240

ucuguuauua uggacuuuca cuauaacgaa aaacggaucu acugggugga ucucgagcgc      300

cagcugcugc agagagucuu ccucaauggg agccggcagg aacgcgugug caacaucgag      360

aagaauguuu ccggaauggc uauuaacugg aucaaugagg aagugauuug gagcaaccaa      420

caggagggca ucauuaccgu cacagacaug aaaggcaaua acucucauau ccugcuuucc      480

gcccugaagu aucccgccaa uguggcugug gauccugucg aaagauuuau uuucuggagc      540

ucugagguug ccgggucccu cuaccgggcu gaccuggaug gagugggcgu gaaagcccuu      600

cuggagacca gcgaaaagau cacagcgguc ucucucgacg ugcuggauaa gcgccuguuu      660

uggauccagu auaacagaga gggguccaau agccucauuu guuccugcga cuacgaugga      720

ggcucuguuc acaucagcaa acaucccacc cagcacaacc uguucgccau gucccuuuuu      780

ggggaccgga uuuucuauag cacguggaag augaaaacca ucuggauugc uaacaagcac      840

acaggaaaag auauggugcg caucaaucug cauucuuccu uugucccucu cggcgaacug      900

aaggugguuc acccgcuugc ccaacccaag gcugaggacg acaccuggga accugagcag      960

aaacugugua agcucagaaa aggcaacugc agcucuacag ugugugggca ggaucugcag     1020

agccaucugu gcaugugugc cgagggauac gcgcucuccc gggaccgcaa guacugcgaa     1080

gaugucaaug agugugccuu cuggaaccac ggcugcaccc uggggugcaa aaauacgccc     1140

ggaucuuauu acuguacaug cccugugggc uucguccuuc ugcccgacgg gaagagaugu     1200

caccaacucg ugagcugccc gcggaacguu uccgaaugua gccaugauug cgugcugacc     1260

ucugagggac cucuuuguuu uugccccgaa ggcuccgucc uggagcgcga cggcaaaaca     1320

uguagcgggu guucuucccc ugauaaugga ggcugcagcc agcucugcgu gccccugucc     1380

cccguuucuu gggagugcga cuguuucccu ggguaugauc ugcagcucga cgaaaagagc     1440

ugcgcugccu ccggaccgca acccuuucug cuuuucgcua acucucagga uaucagacac     1500

augcauuuug acggcaccga cuacgggacc cugcucagcc agcagauggg caugguguau     1560

gcccuggauc acgacccugu cgagaauaag auuuacuucg cccauacagc ucugaaaugg     1620

aucgaacggg cgaacaugga uggaucccaa agagagcgcc uuauugaaga gggcguggac     1680

gugcccgagg ggcucgccgu ugauuggauc ggacggagau uuuauuggac ggaccgcggc     1740

aagagccuga uugggcgguc ugaucugaau ggaaaaagau ccaagaucau caccaaagaa     1800

aacauuagcc agccucgcgg caucgcuguc caccccaugg ccaagcggcu uuucuggaca     1860

gacaccggga uuaauccgag aaucgagucu uccagccugc agggccuugg acgccuggug     1920

auugccucua gcgaucucau cuggccuucc ggcauuacaa ucgacuuucu gaccgauaag     1980

cuguacuggu gugacgcuaa acagagcgug aucgaaaugg ccaaccuuga ugggucuaag     2040

cggagacgcc ucacgcaaaa ugacgucgga caccccuucg cgguggcugu uuuugaggac     2100

uacguguggu ucuccgauug ggccaugccu agcgucaugc gggugaacaa aagaacaggc     2160

aaggaccggg uucgccugca gggguccaug cugaaacccu cuagccucgu ggucgugcau     2220

ccucuggcca agcccggagc ugauccgugc cuuuaucaga acggcgggug ugagcacauu     2280

ugcaagaaaa gacugggcac cgccuggugu uccugccggg aaggauuuau gaaggcuucu     2340

gacggcaaaa ccugucucgc ccuggauggg caucagcugc uugcgggagg cgagguugac     2400

cucaagaauc aagugacacc ucuggauauc cugagcaaaa ccagagucuc cgaagacaac     2460

auuacagagu cucagcacau gcucguggcc gaaaucaugg ugagcgauca ggacgauugc     2520

gcucccgucg gguguuccau guacgcccgc ugcauuagcg agggagagga cgcuacgugc     2580

cagugucuga agggcuucgc cggggauggc aagcucugcu cugacaucga cgaaugugag     2640

augggaguuc ccgugugccc uccggcgucc agcaaaugua ucaauaccga aggcggguau     2700

gugugccggu guucugaggg auaccaaggc gaugggauuc acugccugga caucgaugaa     2760

ugucagcucg gagagcauuc cugcggcgag aacgccagcu guacaaauac cgaaggcggg     2820

uauacaugca ugugcgcugg aagacugucu gagcccggcc ugauuugucc ugacuccacg     2880

cccccucccc accuucgcga agaugaccau cacuacagcg ucagaaacuc cgauagcgag     2940

ugcccucucu cucaugacgg guauugucug cacgauggag ugugcaugua caucgaagcc     3000

cuggacaagu acgcuuguaa uugcguugug ggcuauauug gggagcggug ucaguaccgc     3060

gaucucaaau ggugggagcu gagacacgcc ggacauggcc aacagcagaa ggucaucgug     3120

guugccgugu gcgucguggu ucuugugaug cugcuccugc ugagccuuug gggcgcucac     3180

uauuaccgga cccagaaacu gcucuccaag aaccccaaaa auccguauga agagucuagc     3240

cgcgacguca gaucccggcg cccugcggac accgaagaug ggaugucuag cuguccccaa     3300

ccuugguucg uggugaucaa ggagcaucag gaccugaaga acggaggcca gcccgucgcc     3360

ggggaggaug gacaggcugc cgacggcucc augcaaccga caucuuggag acaggaaccu     3420

cagcucugcg ggaugggaac cgagcagggc uguuggauuc ccguuagcuc cgauaaaggc     3480

agcugcccuc aagugaugga acggucuuuu cacaugcccu ccuacgggac acagacccug     3540

gagggaggcg uggaaaagcc ccauagccuu cugucugcca auccucucug gcagcaacgc     3600

gcucuggacc cgccccacca gauggagcug acgcagugag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  1888
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt5)

<400>  1888
gggagaaagc uuaccaugac cgccggcaga cggauggaga ugcugugcgc ugggcgcgug       60

cccgcccucc ugcuuugucu gggauuccac cuccugcagg cgguccuuag cacaacgguu      120

aucccuuccu gcauuccggg cgaaucuagc gacaacugua ccgcucuggu gcaaacagag      180

gauaauccca gaguggccca ggucuccauc accaagugcu cuagcgacau gaacggguac      240

ugucuccaug gacagugcau uuaucuggug gauauguccc agaauuacug ucggugcgaa      300

guuggcuaua caggggugcg cugugagcac uuuuuccuga ccguccauca accucucucu      360

aaagaauacg uggcccugac aguuauccuu auuauccugu uucucaucac cguggucgga      420

agcacguauu acuucugcag augguaucgg aaccgcaagu ccaaagagcc caagaaagag      480

uacgaaagag ugaccagcgg cgacccugag cugccccagg ugugaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  1889
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt5)

<400>  1889
gggagaaagc uuaccauggc cgagggcgaa aucaccacau ucacggcucu gaccgagaag       60

uuuaaccugc ccccugggaa uuacaaaaag ccgaaacucc uuuauugcag caacggaggc      120

cacuuccugc ggauucuccc cgacgggaca guggauggaa ccagagaccg cuccgaucag      180

cauauccaac ugcagcuuuc ugccgaaagc gucggcgagg uuuacauuaa guccacagaa      240

accgggcagu aucuggcgau ggacacagau ggacuccugu acggcucuca gaccccuaau      300

gaggaguguc uguuucucga aagacuggag gaaaaccacu auaauacgua caucagcaaa      360

aagcaugcug agaagaacug guucgugggc cuuaaaaaga auggguccug caaacgggga      420

ccccgcaccc acuauggcca aaaggccauu cuguuucucc cucugcccgu gucuagcgac      480

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  1890
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt5)

<400>  1890
gggagaaagc uuaccauggu gggcgucggg ggaggcgacg uugaggaugu gacccccaga       60

ccugggggau gccagaucag cggccgcggg gcccggggau guaacggcau uccgggcgcu      120

gccgcguggg aagcugcccu gcccagacgg cgcccuagac ggcaccccuc cgugaauccu      180

cgcucuagag ccgcugggag cccccggaca cgcggaagac ggacggagga acgcccuucc      240

ggcucuagac ucggggaccg gggacgcggc agagcccugc ccgggggacg gcuuggcggc      300

agagggcgcg gacgggcucc cgagagaguc ggcgggcgcg gacggggcag agggaccgcc      360

gcgccucgcg ccgcucccgc cgcucgggga agcagaccug gccccgccgg cacaauggcg      420

gccgggucca ucaccacacu gccggcucuc ccugaagaug gaggcucugg ggccuucccg      480

ccuggacauu uuaaggaccc caaacgccug uacugcaaga acggcggguu cuuucuucgg      540

auucaccccg auggcagagu ggacggaguu cgcgagaaaa gcgauccuca uaucaagcug      600

caacuccagg cugaggaacg gggcgugguc uccauuaaag gggugugugc caauagauau      660

cuggccauga aggaggacgg acggcugcuc gcuagcaagu gcguuaccga ugaauguuuc      720

uuuuucgagc gccuggaguc uaacaauuac aacacauaua gaucccggaa auacaccagc      780

ugguaugugg cgcuuaagag aacgggccag uacaaacugg ggucuaagac cggaccgggc      840

cagaaagcca uccucuuucu gcccaugucc gcuaagagcu gaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  1891
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt5)

<400>  1891
gggagaaagc uuaccaugca caaguggauc cugaccugga uucuccccac acugcuuuac       60

agaagcugcu uccauaucau uugucuggug ggcacgaucu cccucgccug caacgacaug      120

accccugagc agauggcuac aaaugucaac uguucuagcc cggaacggca cacccgcucc      180

uaugauuaca uggaaggggg agacauuaga guucggcgcc uguuuugcag aacacaaugg      240

uaucuucgga ucgauaaacg cggcaaggug aaagggaccc aggagaugaa gaauaacuac      300

aauaucaugg agauuagaac aguggccguc ggaaucgugg cgauuaaagg cguugaaucu      360

gaguucuauc uggcuaugaa caaggagggg aagcucuacg ccaaaaagga auguaaugag      420

gacugcaacu uuaaagaacu gauccuggag aaucauuaua acaccuacgc cagcgcuaag      480

uggacgcaca auggaggcga gauguucgug gcccucaacc agaaaggcau ucccguccgg      540

gggaagaaga ccaaaaagga acagaaaaca gcucauuuuc ugccuauggc caucaccuga      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  1892
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt5)

<400>  1892
gggagaaagc uuaccaugaa gcugcucccc agcguggucc ugaaacuuuu ccuggccgcu       60

guucucuccg cccuggugac cggcgagucu cuugaaagac ugcggcgcgg gcucgcggcu      120

ggaacaagca acccugaccc gcccacggug uccaccgauc agcugcugcc ucucggcggg      180

ggaagagacc ggaagguccg cgaucugcaa gaggccgacc uugaucugcu cagagugaca      240

cugucuagca aaccccaggc ccuugcuacc ccuaauaagg aggaacacgg caaacggaag      300

aagaaaggga agggacuggg caaaaagcgc gaccccugcc ucagaaaaua caaggauuuu      360

uguauccaug gcgaaugcaa guauguuaaa gagcugcggg ccccuuccug uauuugccac      420

ccgggguacc auggagagcg cugucacggc cugucucucc ccguggaaaa cagacuguau      480

acauacgacc auaccacaau ccuugcuguc guggccguug ugcugagcuc cgucugccuc      540

cuggugauug uggggcuucu gauguuccgg uaucaccgca gaggaggcua cgaugucgag      600

aaugaagaga agguuaaacu cgggaugacc aacagccacu gaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  1893
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt5)

<400>  1893
gggagaaagc uuaccaugug ggugaccaag cugcuccccg cccugcuucu gcagcacguc       60

cuccugcauc uucugcuccu gccuaucgcu auuccguacg ccgagggcca aagaaaacgg      120

cgcaacacaa uccacgaguu caagaaaagc gcgaagacga cccugauuaa aaucgacccc      180

gcucucaaga uuaagaccaa aaagguuaau accgccgauc agugcgccaa cagauguaca      240

cggaauaaag ggcugccuuu uaccugcaag gcuuucgugu uugacaaagc ccgcaagcag      300

ugucuuuggu uccccuuuaa cuccaugucu agcggaguga agaaagaguu cggccaugaa      360

uuugaucugu augagaauaa ggacuacauc agaaacugca ucauugggaa aggacggucc      420

uauaagggca cagucucuau caccaaaagc gggauuaagu gucagccuug guccucuaug      480

aucccccacg aacauagcuu ccucccuucc agcuaccgcg gaaaagaucu gcaagagaau      540

uauugcagaa acccgcgggg cgaggaaggc gggcccuggu guuuuacguc uaauccugag      600

gugcgcuacg aaguuugcga cauuccccag uguuccgagg uggagugcau gaccuguaac      660

ggagaaagcu auagaggccu uauggaucac acagagucug ggaagaucug ccagcggugg      720

gaccaccaga ccccucaucg ccacaaguuc cugcccgaaa gauacccgga uaaaggauuu      780

gacgauaauu acugccggaa cccugacggc caaccccgcc cuugguguua uacacucgau      840

ccccauacaa gaugggaaua cugcgcuauu aagacgugug ccgacaauac aaugaacgac      900

accgaugucc cccuggaaac aaccgagugc auccaggggc agggagaggg cuaucggggc      960

accgugaaua caaucuggaa cgggauuccu ugucagagau gggacuccca auacccgcac     1020

gaacacgaua ugacgcccga gaacuucaaa ugcaaggacc ugcgcgaaaa uuauugucgg     1080

aacccugaug gaagcgaguc ucccuggugc uuuaccacag acccuaauau cagaguuggc     1140

uacuguuccc agauucccaa cugcgauaug agccaugggc aggacuguua ucgcggaaau     1200

ggcaaaaacu acauggggaa ucucucccaa acccggucug gacugacaug cagcaugugg     1260

gauaagaaca uggaagaccu ucacagacau aucuucuggg agccggaugc guccaagcug     1320

aaugagaacu acugccgcaa uccugacgac gaugcccacg gccccuggug uuauaccggc     1380

aacccucuca uucccuggga cuacugcccu aucagccggu gugaagggga uacgacaccc     1440

accaucguga aucuggacca uccggucauu ucuugcgcua aaaccaagca gcuuagagug     1500

gugaacggaa ucccuacacg caccaauauu ggcuggaugg ucucccugcg guauagaaac     1560

aaacacaucu gugggggaag ccucauuaag gagucuuggg uucugacagc ccgccagugc     1620

uuccccagcc gggaucugaa agacuacgag gcuuggcucg gcauccacga ugugcauggg     1680

agaggcgacg aaaaguguaa acaggugcug aacgucuccc aacuugugua uggacccgaa     1740

ggcucugauc ugguucucau gaagcuggcc cggccugcgg ugcuugacga uuuugucagc     1800

acgaucgacc ugccgaauua cgggugcacc auucccgaga agacauccug uagcguguau     1860

ggauggggcu acaccgggcu caucaacuac gauggacugc ugcgcguugc ccaccucuau     1920

auuaugggca augagaaaug cucucagcau cacagaggga aggugacacu gaacgaaucc     1980

gagaucugug cuggcgccga gaaaauugga agcggcccuu gcgaagggga cuacggaggc     2040

ccccuugucu gcgagcagca caagaugcgg auggugcugg gggucaucgu gccuggaaga     2100

ggcugugcua uucccaaucg cccugggauc uucguucggg uggccuauua cgccaagugg     2160

auccauaaaa uuauccucac cuauaagguc ccccagucuu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  1894
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt5)

<400>  1894
gggagaaagc uuaccauggc caaggcugcc gcgaucggca uugaccuggg gaccacauac       60

agcugcgugg gagucuucca gcacggcaaa guugagauca uugcuaacga ucaagggaau      120

agaacgaccc ccuccuaugu ggccuuuaca gacaccgaac ggcucaucgg agaugccgcu      180

aagaaccagg uggcccugaa uccucagaac acagucuucg acgcuaaacg ccuuauuggc      240

agaaaguuug gggauccggu gguucagucu gacaugaaac auuggcccuu ccaagugauc      300

aaugauggag acaagccuaa gguccaggug agcuacaaag gcgagaccaa ggccuuuuau      360

cccgaagaga ucuccucuau gguucugaca aaaaugaagg aaauugcgga ggccuaccuc      420

ggcuauccug ugaccaacgc ugucaucacg gugcccgccu acuucaauga uagccagcgg      480

caggcuacca aagacgccgg ggugauugcg ggacugaacg uccuucgcau cauuaaugag      540

ccuacagccg cugccaucgc uuauggccug gauagaaccg ggaagggaga acggaacguu      600

cucauuuuug accugggcgg gggaacauuc gaugugucca uccugaccau cgacgacggc      660

auuuuugagg ugaaggccac ggccggcgau acacaccucg ggggagaaga cuucgauaau      720

cgccugguca accauuuugu ggaggaguuc aaaagaaagc acaaaaagga caucucucaa      780

aauaaacggg cuguucgcag acuucggacc gcgugugaac gcgccaagag aacacugagc      840

uccagcaccc aggcuucucu cgagauugau ucccuguuug aaggcaucga cuucuacacc      900

agcauuacac gggcccgcuu cgaggaacuu ugcucugauc uguuuagauc cacgcucgag      960

ccgguggaga aagcccugcg ggacgcuaag cuggauaagg cccagaucca ugaccucguc     1020

cugguugggg gaagcaccag aauccccaaa gugcagaaac uucugcaaga uuucuuuaac     1080

ggccgcgacc ucaauaaguc uauuaacccu gacgaagcgg uggcuuacgg ggccgccguc     1140

caggcugcca uccugauggg agauaagucc gagaacgugc aggaccuucu gcuccuggau     1200

gucgcucccc ugagccucgg ccuggaaaca gccggcgggg ugaugaccgc gcuuauuaaa     1260

cggaauagca caaucccuac caagcaaacg cagauuuuca caaccuauuc ugacaaccag     1320

cccggaguuc ugauccaggu guacgagggc gaaagagcca ugaccaagga uaauaaccuc     1380

cuggggcgcu uugagcuuag cggaaucccg ccugcucccc ggggcguccc ucaaauugag     1440

gugacauucg acaucgaugc caaugggauu cugaacguua ccgcuacaga caaauccacg     1500

ggcaaggcca auaaaaucac cauuacaaac gauaagggaa gacucagcaa agaagagauc     1560

gaacgcaugg ugcaggaggc ggaaaaguau aaggccgagg acgaggucca gcgggaaaga     1620

gugucugcua aaaaugcccu ggaguccuac gcuuuuaaca ugaaguccgc cguggaagau     1680

gagggccuga aagggaagau uucugaggcc gacaaaaaga agguucucga uaaaugucag     1740

gaagucauca gcuggcugga cgcuaauacc cuugcggaga aggacgaguu cgaacacaaa     1800

cgcaaggaac uggagcaagu gugcaacccc aucauuuccg gacucuauca gggcgccggg     1860

ggacccggcc cugggggcuu uggagcucag ggcccgaaag ggggaucugg cagcgggccc     1920

acaaucgagg aaguggauug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1895
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt5)

<400>  1895
gggagaaagc uuaccauggc caaggcugcc gcgaucggca uugaccuggg gaccacauac       60

agcugcgugg gagucuucca gcacggcaaa guugagauca uugcuaacga ucaagggaau      120

agaacgaccc ccuccuaugu ggccuuuaca gacaccgaac ggcucaucgg agaugccgcu      180

aagaaccagg uggcccugaa uccucagaac acagucuucg acgcuaaacg ccuuauuggc      240

agaaaguuug gggauccggu gguucagucu gacaugaaac auuggcccuu ccaagugauc      300

aaugauggag acaagccuaa gguccaggug agcuacaaag gcgagaccaa ggccuuuuau      360

cccgaagaga ucuccucuau gguucugaca aaaaugaagg aaauugcgga ggccuaccuc      420

ggcuauccug ugaccaacgc ugucaucacg gugcccgccu acuucaauga uagccagcgg      480

caggcuacca aagacgccgg ggugauugcg ggacugaacg uccuucgcau cauuaaugag      540

ccuacagccg cugccaucgc uuauggccug gauagaaccg ggaagggaga acggaacguu      600

cucauuuuug accugggcgg gggaacauuc gaugugucca uccugaccau cgacgacggc      660

auuuuugagg ugaaggccac ggccggcgau acacaccucg ggggagaaga cuucgauaau      720

cgccugguca accauuuugu ggaggaguuc aaaagaaagc acaaaaagga caucucucaa      780

aauaaacggg cuguucgcag acuucggacc gcgugugaac gcgccaagag aacacugagc      840

uccagcaccc aggcuucucu cgagauugau ucccuguuug aaggcaucga cuucuacacc      900

agcauuacac gggcccgcuu cgaggaacuu ugcucugauc uguuuagauc cacgcucgag      960

ccgguggaga aagcccugcg ggacgcuaag cuggauaagg cccagaucca ugaccucguc     1020

cugguugggg gaagcaccag aauccccaaa gugcagaaac uucugcaaga uuucuuuaac     1080

ggccgcgacc ucaauaaguc uauuaacccu gacgaagcgg uggcuuacgg ggccgccguc     1140

caggcugcca uccugauggg agauaagucc gagaacgugc aggaccuucu gcuccuggau     1200

gucgcucccc ugagccucgg ccuggaaaca gccggcgggg ugaugaccgc gcuuauuaaa     1260

cggaauagca caaucccuac caagcaaacg cagauuuuca caaccuauuc ugacaaccag     1320

cccggaguuc ugauccaggu guacgagggc gaaagagcca ugaccaagga uaauaaccuc     1380

cuggggcgcu uugagcuuag cggaaucccg ccugcucccc ggggcguccc ucaaauugag     1440

gugacauucg acaucgaugc caaugggauu cugaacguua ccgcuacaga caaauccacg     1500

ggcaaggcca auaaaaucac cauuacaaac gauaagggaa gacucagcaa agaagagauc     1560

gaacgcaugg ugcaggaggc ggaaaaguau aaggccgagg acgaggucca gcgggaaaga     1620

gugucugcua aaaaugcccu ggaguccuac gcuuuuaaca ugaaguccgc cguggaagau     1680

gagggccuga aagggaagau uucugaggcc gacaaaaaga agguucucga uaaaugucag     1740

gaagucauca gcuggcugga cgcuaauacc cuugcggaga aggacgaguu cgaacacaaa     1800

cgcaaggaac uggagcaagu gugcaacccc aucauuuccg gacucuauca gggcgccggg     1860

ggacccggcc cugggggcuu uggagcucag ggcccgaaag ggggaucugg cagcgggccc     1920

acaaucgagg aaguggauug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1896
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt5)

<400>  1896
gggagaaagc uuaccauggc caccgcuaag ggcaucgcca uugggaucga ccugggaaca       60

acguacagcu gcgugggcgu cuuccagcac gggaagguug agauuaucgc gaacgaucaa      120

ggaaauagaa ccacacccuc cuauguggcu uuuaccgaca cagaacggcu cauuggcgau      180

gccgccaaga accagguggc uaugaauccu cagaacaccg ucuucgacgc caaacgccug      240

aucgggagaa aguuuaauga uccggugguu caggcugaca ugaaacuuug gcccuuccaa      300

gugaucaacg agggaggcaa gccuaagguc cuggugucuu acaaaggcga aaauaaggcc      360

uuuuaucccg aggaaauuag cuccaugguu cucacaaaac ugaaggagac cgcggaggcc      420

uuccuugggc auccugugac gaacgcuguc aucaccgugc ccgccuacuu uaaugauucu      480

cagcggcagg cuacaaaaga cgccggagug auugcgggcc ugaacguccu ccgcaucauu      540

aaugaaccua ccgccgcugc caucgcuuau gggcuggaua agggaggcca gggggagaga      600

cacguucuga uuuucgaccu cggaggcggc acauuugaug ugagcauccu gaccaucgac      660

gaugggauuu ucgaagugaa ggccacggcc ggagacacac aucuuggcgg ggaggacuuu      720

gauaaccggc uggucuccca cuucguggag gaauuuaaac gcaagcauaa aaaggacauc      780

ucucaaaaua aaagagcugu ucggcgccuc agaaccgcgu gugagcgggc caagcgcaca      840

cugagcucca gcacccaggc uaaccuugaa auugauucuc uguacgaggg aaucgacuuc      900

uauaccucca uuacaagagc ccgguucgag gaacucugcg ccgaucuguu ucgcggcacg      960

cuggagccgg uggaaaaagc ucucagagac gccaagaugg auaaggcgaa aauccacgac     1020

aucguccugg uugggggaag cacccggauu cccaaggugc agagacuucu gcaggauuac     1080

uucaauggcc gcgaccucaa caaaucuauc aacccugaug aggcuguggc cuacggcgcc     1140

gcuguccaag ccgcuauucu gaugggggac aaguccgaaa aagugcagga ccuucugcuc     1200

cuggaugucg cgccccugag ccucggacug gagacagccg gcggggugau gaccgcccuu     1260

aucaagcgga auagcacaau uccuaccaag cagacgcaaa ucuuuacaac cuauuccgac     1320

aaccagcccg gaguucugau ccagguguac gaaggcgaga gagcuaugac caaagauaau     1380

aaccuccugg ggcgcuucga ccuuacaggc auuccgccug cuccccgggg agucccucag     1440

aucgagguga ccuuugauau ugacgccaau ggcauccuga acguuacagc cacggauaag     1500

agcaccggga aagugaauaa gauuacaauc accaacgaca aaggaagacu cuccaaggaa     1560

gagauugaac gcaugguccu ggaugcggag aaguauaaag ccgaagacga ggugcaacgg     1620

gagaagaucg cugccaaaaa ugcucuggaa ucuuacgccu ucaacaugaa gucugugguu     1680

uccgaugagg gccucaaagg gaagaucagc gaaucugaca agaauaaaau ucuggauaag     1740

uguaacgagc uucuguccug gcucgagguc aaucagcugg ccgaaaaaga cgaguuugac     1800

cacaagagaa aagaacugga gcagaugugc aaccccauca uuacaaaacu uuaucaggga     1860

ggcuguaccg ggcccgcuug cggcacggga uacgugccug gccgcccggc gaccgggccc     1920

acaaucgaag agguggauug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1897
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt5)

<400>  1897
gggagaaagc uuaccaugag cgccagaggc cccgcuaucg ggauugaccu gggaaccaca       60

uacuccugcg ugggcgucuu ccagcacggg aagguugaga ucauugccaa cgaucaagga      120

aaucggacga ccccuucuua uguggcguuu acagacaccg aacgccucau cggcgaugcu      180

gccaaaaacc agguggccau gaauccgaca aacaccauuu ucgacgcuaa gagacugauc      240

gggcggaaau uugaggaugc cacaguccag agcgacauga agcauuggcc cuuccgcgug      300

guuuccgaag gaggcaaacc uaaggugcag gucgaguaca agggcgaaac caaaacguuu      360

uuccccgagg agaucucuag cauggugcuu accaagauga aagaaauugc ugaggccuau      420

cugggaggaa agguucacuc cgcggugauc acagucccug ccuacuuuaa ugauucucaa      480

agacaggcua ccaaagacgc cggcacaauu accgggcuca acgugcugcg gaucauuaau      540

gaacccacgg cugccgcgau cgccuaugga cuugauaaga agggcugugc ugggggagag      600

aaaaacgugc ugauuuucga ccucggcggc gggacauuug augucagcau ccugaccauc      660

gaggacggaa uuuucgaagu uaaguccaca gccggcgaua cccaucuugg gggagaggac      720

uuugacaauc gcauggugag ccaccucgcu gaagaguuca aaagaaagca uaaaaaggau      780

aucggcccua acaaacgggc cgugcgcaga cugcggaccg ccugcgaacg cgcuaagaga      840

acacuuucuu ccagcacgca ggcgucuauu gagaucgacu cccuguacga gggggucgau      900

uuuuauacca gcauuacacg ggcccgcuuc gaggaacuca augcugaccu guucagagga      960

acccuugaac cgguggagaa ggcccugcgg gaugccaaac ucgacaaggg ccagauccaa     1020

gaaaucguuc uggugggcgg gucuacacgc auucccaaaa uccagaagcu gcuccaggac     1080

uuuuucaacg gaaaagagcu gaauaagucc auuaacccug augaggcugu cgccuacggc     1140

gcggcugugc aggccgccau ccuuauuggg gauaagagcg aaaauguuca agaccugcuc     1200

cugcuugaug ugacgccccu gucccucgga aucgagaccg cuggcggggu caugacaccu     1260

cugaucaaaa gaaacaccac cauucccaca aagcagaccc agacauuuac gaccuacucu     1320

gacaaccaaa gcuccgugcu gguccaggug uaugaaggcg agcgggccau gacaaaagac     1380

aauaaccucc ugggaaaguu cgaucuuacc ggcaucccgc cugcucccag agggguuccu     1440

cagauugaag ugacauuuga caucgaugcc aaugggauuc ugaacgucac cgcggccgac     1500

aaaagcacgg gcaaggagaa uaagaucacc auuacaaacg auaaagggcg ccucucuaag     1560

gacgauaucg accggauggu gcaggaggcu gaaagauaca aauccgagga ugaagccaau     1620

cgcgaccggg uugcugccaa gaacgcgcug gagagcuaua ccuacaauau caaacaaaca     1680

guggaggaug aaaagcugag aggaaagauu ucugagcagg acaaaaacaa gauccuggau     1740

aaaugucagg aagucauuaa uuggcucgac cgcaaccaga uggccgagaa ggacgaauau     1800

gagcacaaac aaaaggagcu ggaacgggug ugcaauccca ucauuagcaa acuguaccag     1860

ggcgggcccg gcggaggcuc cgggggaggc gggucuggag cuagcggcgg gccuaccauc     1920

gaggaagugg auugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  1898
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt5)

<400>  1898
gggagaaagc uuaccaugag cguggucggc aucgaccugg gguuccaguc cugcuacguu       60

gccguggcua gagccggagg cauugagacc aucgcgaacg aauauucuga ucgguguaca      120

cccgcuugca uuagcuuugg gccuaagaau cgcuccaucg gagccgccgc uaaaucucaa      180

gugauuagca acgccaagaa uacgguccag ggcuucaaaa gauuucacgg gcgggcuuuc      240

uccgacccgu uuguggaggc cgaaaagucu aaccucgcgu acgauaucgu ucagcugccc      300

accggacuua caggcaucaa agugaccuau auggaggaag aacgcaauuu cacaaccgag      360

caggucacag ccaugcugcu cagcaagcug aaggaaaccg cugaguccgu gcuuaaaaag      420

ccuguugugg acugugucgu gagcgugccc ugcuuuuaca cggaugccga aagacggucu      480

gucauggacg cuacccaaau ugccggccug aacugucucc gccugaugaa ugagacaacc      540

gcgguugccc uggcuuaugg gaucuacaaa caggaucucc cugcccugga ggaaaagccc      600

agaaacgugg uguucgucga caugggacau uccgcuuauc aggugagcgu uugcgccuuu      660

aaucggggca aacuuaaggu gcuggccaca gcuuucgaua ccacgcucgg gggacgcaag      720

uuugacgagg uccuggugaa ccacuucugu gaagaguuug gcaaaaagua caaacuugau      780

auuaagucua aaaucagagc gcugcuccgg cugucccagg aaugcgagaa gcugaaaaag      840

cucaugagcg ccaaugcuuc ugaccugccu cuuuccauug aguguuucau gaacgauguu      900

gacgugagcg ggacaaugaa ucgcggaaag uuccuggaaa ugugcaacga ccuccuggcc      960

agagucgagc cgccccuucg guccgugcug gaacaaacca aacucaagaa agaggauauc     1020

uacgccgucg aaauuguggg cggcgcuaca cgcaucccug ccguuaagga gaaaaucucu     1080

aaguuuuucg ggaaggagcu gagcaccacc cugaaugcgg acgaagcugu gacaagagga     1140

ugugcccucc agugcgccau ucuguccccc gcuuuuaaag uccgggaguu cagcaucacg     1200

gaugugguuc cuuaucccau uucucuuaga uggaacuccc cggccgaaga gggcagcucu     1260

gacugcgaag uguuuagcaa gaaccaugcu gccccuuucu ccaaaguccu gaccuuuuac     1320

cgcaaggagc ccuucacacu cgaggcguau uacucuagcc cucaggaucu gcccuauccc     1380

gacccugcca ucgcucaguu uuccgugcaa aaagugaccc cgcagagcga ugggucuucc     1440

agcaagguua aggucaaagu gcgggugaau guccacggaa uuuucucugu guccagcgcc     1500

ucccuuguug aagugcauaa gucugaggaa aacgaggagc ccauggaaac agaccagaau     1560

gcuaaagagg aagagaagau gcaagucgau caggaggagc cucacgugga ggaacagcag     1620

caacagaccc ccgccgagaa caaagcggaa agcgaggaaa uggagacguc ccaggccggc     1680

ucuaaggaca agaaaaugga ucagccuccc caagcuaaga aagccaaggu uaaaacaagc     1740

accguggacc ugccgaucga gaaucagcuc cuguggcaga ucgacagaga aaugcugaac     1800

cucuacauug agaaugaagg gaagaugauc augcaggaua aacuggagaa ggaacgcaac     1860

gacgcuaaga augccgucga ggaguaugug uacgaaaugc gggauaaacu uuccggagag     1920

uacgaaaagu uuguuagcga ggacgauaga aacucuuuca cccugaaacu cgaggacaca     1980

gaaaauuggc uguaugagga uggcgaagac caaccuaaac agguguacgu cgauaagcug     2040

gccgagcuua agaaccucgg ccagcccauu aagauccgcu uucaggaauc cgaggagcgg     2100

ccuaaacugu ucgaggaacu ggggaagcaa auucagcagu auaugaaaau caucagcucu     2160

uucaagaaua aagaagacca auacgaucac cucgacgcug cggauaugac caagguggag     2220

aaguccacaa acgaagccau ggaguggaug aauaacaaac ugaaccuuca gaauaagcag     2280

agccugacga uggaccccgu ggucaaaucu aaggagauug aagcuaaaau caaggagcuc     2340

accagcacau guuccccuau uaucagcaag cccaaaccga agguugaacc ucccaaagag     2400

gaacagaaga acgccgagca aaauggaccc guggacggcc agggggauaa cccuggaccg     2460

caggccgcug agcagggcac cgacacagcc gugcccucug auuccgacaa aaagcugccu     2520

gaaauggaua uugacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  1899
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt5)

<400>  1899
gggagaaagc uuaccaugag cguggucggc aucgaccugg gguuccucaa cugcuacauu       60

gccguugcua gauccggagg caucgagacc auugccaaug aauauucuga ucgguguaca      120

cccgcgugca ucagccuggg gucccgcacg agagcuauug gaaacgccgc caagucucag      180

aucgugacca augugcggaa cacaauccac ggcuuuaaaa agcugcaugg gcgcagcuuc      240

gacgauccua uuguccaaac cgagagaauc cggcuuccgu acgaacucca gaaaaugccc      300

aauggauccg cuggcgugaa gguucgcuau cuggaggaag agagaccuuu ugccauugaa      360

caggugacag gcaugcuucu ggcuaaacuc aaggagaccu cugagaacgc ccugaagaaa      420

cccgucgcgg acugugugau cagcauuccu uccuucuuua cagaugccga acggcgcagc      480

guuauggcug ccgcucaggu ggccgggcug aauugccuca gacugaugaa cgagaccacg      540

gcggucgccc uugcuuacgg aaucuauaag caagaccugc ccccucucga ugagaaaccg      600

cggaaugugg uguucauuga caugggccac ucugccuacc agguccuggu uugugcuuuu      660

aacaagggga aacuuaaggu gcuggccacc acauucgauc ccuaucucgg aggccgcaau      720

uuugacgaag cccuggugga uuacuucugc gacgaguuua agaccaaaua caagaucaac      780

gucaaagaaa auuccagagc ucugcuccgg cuguaucagg agugugaaaa acuuaagaag      840

cugaugagcg cgaacgccuc ugaucucccu cugaauaucg agugcuucau gaacgaccuu      900

gacgugucca gcaaaaugaa ccgcgcucag uuugagcaac ugugugccuc ucuccuggcc      960

agaguugaac ccccucugaa ggcugugaug gagcaggcca aucuccagcg ggaagauauu     1020

uccagcaucg agauugucgg gggagcgaca agaauccccg cugugaagga acagauuacc     1080

aaauucuucc ugaaggacau cuccacgaca cuuaacgccg augaggccgu ugcucgcggc     1140

ugcgcccugc aaugugcuau ccucucuccg gccuuuaaag ugcgggaguu cagcauuacc     1200

gaccuggucc cuuacuccau cacacuuaga uggaagacca gcuuugaaga uggcucuggg     1260

gagugcgaag uguucugcaa aaaucauccc gcgccuuuuu ccaaggucau uaccuuccac     1320

aagaaagagc ccuuugaacu ggaggccuuc uauacaaacc uccaugaggu gcccuacccu     1380

gacgcucgca ucggcagcuu uacgauucag aauguuuucc cgcagucuga uggagacagc     1440

uccaagguga aagucaaggu gcggguuaac auccacggga ucuuuucugu ggccagcgcu     1500

uccgucauug aaaaacaaaa ucuggaggga gaucacagcg acgcccccau ggaaaccgag     1560

acaucuuuca agaacgagaa uaaggauaac auggacaaaa ugcaagugga ccaggaagag     1620

ggccaucaga agugucacgc ggaacauacc ccugaggaag agaucgauca cacaggggcc     1680

aaaaccaagu ccgcugugag cgacaaacag gauagacuga aucagacgcu caagaaggga     1740

aaaguuaagu cuauugaccu gcccauccag uccagccuuu gccgccagcu gggccaagau     1800

cuccugaacu ccuauauuga gaaugaaggc aaaaugauca ugcaggacaa gcuggagaaa     1860

gaacggaacg augccaagaa ugcugucgag gaauacgugu augacuuuag agaucgccuu     1920

gggacagugu acgagaaauu cauuaccccu gaggaccucu cuaagcugag cgccguccug     1980

gaagauaccg agaacuggcu cuacgaagac ggagaggauc agcccaaaca gguguauguu     2040

gacaagcugc aagaacuuaa gaaauacggc cagccgaucc agaugaagua uauggagcac     2100

gaggaacggc cuaaagcccu gaacgaccuc gggaagaaga uccagcuggu gaugaaaguc     2160

auugaggcuu acagaaauaa ggaugaacgc uaugaccauc uggaucccac agagauggag     2220

aaaguggaaa aguguaucuc cgacgcgaug ucuuggcuua acagcaaaau gaaugcccaa     2280

aacaagcucu cccugaccca ggauccuguu gugaagguca gcgagauugu ggcuaaaucu     2340

aaggaacugg acaauuucug caaccccauc auuuacaaac cuaagcccaa agccgagguu     2400

ccggaagaua agccuaaggc caauuccgag cacaacggac ccauggacgg ccagagcggg     2460

acagagacga aaucugauuc caccaaggac agcucucaac auacaaaaag cuccggcgaa     2520

auggaggugg auugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  1900
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt5)

<400>  1900
gggagaaagc uuaccaugaa gcugagccuc guggccgcua ugcugcuucu gcucuccgcc       60

gcgagagcug aggaagagga caaaaaggaa gaugucggca ccguuguggg gaucgaccug      120

ggaacaacgu acucuugcgu gggcgucuuc aaaaacgggc ggguggagau uaucgccaau      180

gaucagggaa accgcauuac ccccagcuau guugccuuua caccugaagg cgagagacuu      240

aucggggacg cugccaagaa ucaacugacc uccaacccgg agaauacagu guucgaugcu      300

aaacggcuca uuggacgcac cuggaacgac cccucugucc agcaggauau caaguuucug      360

ccuuucaagg ugguugaaaa gaagacaaaa cccuacaucc agguggacau uggcggcggg      420

caaaccaaga cguuugcccc ugaggaaauc agcgcgaugg uccugaccaa aaugaaggag      480

acagccgagg cuuaucucgg aaagaaagug acccacgccg uggucacagu ucccgcuuac      540

uucaaugaug cccagagaca ggcgaccaag gacgccggca cgauugcugg gcugaacgug      600

augcggauca uuaaugaacc uacagccgcu gccaucgccu auggacuuga uaaacgcgag      660

ggcgaaaaga acauucuggu guuugaccuc gggggaggca ccuucgaugu cucccugcuu      720

acaaucgaca auggcguguu ugagguugug gcuaccaacg gggacaccca ucugggaggc      780

gaagauuucg accagagagu cauggagcac uuuaucaaac ucuacaagaa aaagacaggg      840

aaggaugugc ggaaagacaa ucgcgcgguu caaaagcuga gacgggaggu ggaaaaagcc      900

aagcgcgcuc ugucuagcca gcaucaggcc agaauugaga ucgaauccuu cuaugaggga      960

gaagauuuua gcgagacgcu cacccgggcc aaauucgagg aacugaacau ggaccuuuuc     1020

cgcucuacaa ugaagccggu ccagaaggug cuggaggauu ccgaccucaa aaagagcgau     1080

auugacgaaa ucguccuggu gggcgggucu acccggauuc ccaaaaucca acagcuuguu     1140

aaggaguuuu ucaauggaaa agaaccuucc agaggcauca accccgauga ggcuguggcc     1200

uacggcgcgg cuguccaggc cggggugcug agcggagacc aagacacagg cgaucucguu     1260

cugcuggacg uguguccucu cacccugggg auugagacgg ucggaggcgu gaugacaaaa     1320

cuuaucccca gaaacaccgu gguuccgacc aagaaaucuc agaucuuuuc cacagccagc     1380

gauaaucagc cuaccgucac aauuaaggug uacgaagggg agcgcccccu gacgaaagac     1440

aaccaccucc ugggcaccuu cgaucuuaca ggcauuccuc ccgcuccccg gggagugccu     1500

cagaucgaag ucaccuuuga gaucgacgug aaugggauuc ugagaguuac agccgaggau     1560

aagggaaccg gcaacaaaaa uaagaucacg auuaccaacg accaaaaucg ccucacaccg     1620

gaagagaucg aacggauggu gaacgaugcu gagaaguucg ccgaagagga caaaaagcug     1680

aaagagagaa uugauacccg caaugaacug gaguccuaug cguacucucu caagaaccag     1740

aucggggaca aagaaaagcu gggaggcaaa cuuagcuccg aggauaagga aacaauggag     1800

aaggccgucg aggagaaaau ugaauggcug gaaagccauc aggacgcuga caucgaggau     1860

uuuaaggcca aaaagaaaga acucgaggag aucgugcagc ccauuaucuc uaagcuguau     1920

ggguccgcug gcccuccccc uaccggagaa gaggacacgg ccgaaaagga ugagcuguga     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  1901
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt5)

<400>  1901
gggagaaagc uuaccaugca ggcccccaga gagcuggcug ugggcaucga ccucgggacc       60

acauacagcu gcgucggagu uuuccaacag ggccgggugg aaauucuggc caacgaucag      120

gggaaucgca cgaccccuuc cuauguggcg uuuacagaca ccgagagacu ugucggagau      180

gcugccaagu cucaggccgc ucugaacccg cacaauacag uguucgacgc caaacggcuc      240

aucggccgca aguuugcuga uaccacaguu caaagcgaca ugaaacauug gcccuucaga      300

guggucuccg aagggggaaa gccuaaagug cggguuuguu accgcggcga ggauaagacc      360

uuuuaucccg aagagauuuc uagcauggug cuguccaaga ugaaagagac ggccgaagcg      420

uaccuuggcc agccugucaa gcacgccgug aucaccgugc ccgcuuauuu caacgacucu      480

cagagacagg ccacaaaaga ugcuggggcc auugcgggac ugaauguccu ccggaucauc      540

aacgagccua ccgccgcugc cauugcuuac ggccuggacc gcagaggggc cggagaacgg      600

aauguucuga ucuuugaucu cggcggggga acauucgacg ugagcgugcu guccauugau      660

gccggcgucu uugaggugaa ggcuaccgcg ggcgacacgc aucuuggggg agaggacuuc      720

gauaaccgcc ugguuaauca cuuuauggaa gaguucagac ggaaacaugg caaggaccuc      780

agcgggaaca agcgcgcccu gagacggcuu agaacagcuu gcgaacgcgc caaacggacc      840

cugucuucca gcacacaagc cacccucgag aucgauucuc uguuugaagg aguggacuuc      900

uauaccucca uuacaagagc ucgcuucgag gagcugugua gcgaucucuu ucggucuacg      960

cuggaaccgg ucgagaaggc ccuuagagac gcgaaacugg auaaggcuca gauccacgac     1020

gugguucucg ugggcggguc cacccgcauu cccaaagucc agaagcugcu ucaggauuuc     1080

uuuaauggaa aagaacugaa caagagcauc aauccugacg aggccguggc cuacggcgcu     1140

gccguccaag cugccgugcu caugggcgau aagugcgaaa aaguucagga ccugcugcuc     1200

cuggacgugg cgccccuuuc ccuggggcuc gagacagccg gaggcgucau gaccacacug     1260

auccagcgga acgcuaccau uccuacgaag caaacacaga ccuucaccac auacucugau     1320

aaucagcccg ggguguuuau ccagguuuau gagggagaaa gagccaugac caaagacaac     1380

aaccuucugg gccgcuucga gcucagcggg auuccgccug cuccccgggg cgugccucaa     1440

aucgaaguca cauuugauau ugacgccaau ggaauccugu ccgugacggc gaccgauaga     1500

agcacaggca aggccaacaa aaucaccauu acaaaugaca aggggcgccu gucuaaggag     1560

gaaguggagc ggaugguuca cgaggcugaa caguacaaag ccgaggauga agcucagaga     1620

gaccgggucg ccgccaagaa cucccucgag gcucaugugu uccacgugaa aggaagccug     1680

caggaggaau cucuucgcga uaagaucccc gaggaagaca gacggaaaau gcaagauaag     1740

uguagagagg uccuggcgug gcucgaacau aaucagcugg ccgagaagga ggaauaugag     1800

caccagaaac gcgaacugga gcagauuugc cggcccaucu uuagcagacu uuacggcggg     1860

ccuggagugc cgggcggguc cucuuguggc acccaagcuc gccagggaga ccccagcacg     1920

ggcccuauua ucgaagaggu ugauugagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  1902
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt5)

<400>  1902
gggagaaagc uuaccaugca ggcccccaga gagcuggcug ugggcaucga ccucgggacc       60

acauacagcu gcgucggagu uuuccaacag ggccgggugg aaauucuggc caacgaucag      120

gggaaucgca cgaccccuuc cuauguggcg uuuacagaca ccgagagacu ugucggagau      180

gcugccaagu cucaggccgc ucugaacccg cacaauacag uguucgacgc caaacggcuc      240

aucggccgca aguuugcuga uaccacaguu caaagcgaca ugaaacauug gcccuuccag      300

guggucuccg aagggggaaa gccuaaagug agaguuuguu accggggcga ggauaagacc      360

uuuuaucccg aagagauuuc uagcauggug cuguccaaga ugaaagagac ggccgaagcg      420

uaccuuggcc agccugucaa gcacgccgug aucaccgugc ccacauauuu cucuaacagc      480

cagcgccaag cuaccaaaga cgccggggcu auugccggac ugaagguccu cccuaucauc      540

aaugaggcga cagccgcugc cauugcuuac ggccuggaua gacgcggggc cggaaaacgg      600

aacguucuga ucuuugaccu cggcggggga accuucgaug uguccgugcu gagcauugac      660

gccggcgucu uugaagugaa ggcuacggcg ggcgauacac aucuuggggg agaggacuuc      720

gacaauagac ugguuaacca cuuuauggag gaguuccggc gcaagcaugg caaagaucuc      780

ucugggaaua agagagcccu gcggcgccuu agaaccgcuu gcgagcgggc caaaagaaca      840

ccguccagcu cuacccaggc cacccuggaa aucgacuccc ucuuugaggg aguggauuuc      900

uauaagagca uuacacgcgc ucgguucgaa gaacuguguu cugaccuguu uagauccacg      960

cucgagcccg ucgaaaaagc ccugcgcgau gcgaaacuug acaaggcuca gauccacgau     1020

uucgugcugg gcgggggacu ccacagccau ccucagggcg ccgagguugc cgcuggccug     1080

cuucaacggc agggggccga acaggagcac caacccugag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  1903
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt5)

<400>  1903
gggagaaagc uuaccaugag caagggcccc gccgugggga ucgaccuggg aaccacauac       60

uccugcgucg gcguuuucca gcacgggaaa guggagauua ucgcuaacga ucaaggaaau      120

agaacgaccc cuucuuaugu ggccuuuaca gacaccgaac ggcucauugg cgaugcggcu      180

aagaaccagg ucgccaugaa uccgacaaac accguguucg acgccaaacg ccugaucggg      240

agacgguuug augacgcugu ugugcagagc gauaugaagc auuggcccuu cauggucgug      300

aaugacgccg gacgcccuaa aguucaggug gaguacaagg gcgaaacaaa guccuuuuau      360

cccgaggaag ucucuagcau ggugcuuacc aaaaugaagg agauugcuga ggccuaccug      420

ggcaaaacgg ugaccaacgc ggucguuaca gugccugccu auuucaauga uucccaaaga      480

caggcuacca aggacgccgg gacaaucgcu ggacucaacg ugcugcggau cauuaaugaa      540

cccaccgccg cggccaucgc uuacggccuu gauaaaaagg ucggggccga gcgcaacgug      600

cugauuuuug accucggagg cgggacguuc gauguuucua uccugacaau ugaagacgga      660

aucuuugagg ugaagucuac cgcuggcgac acacaccugg gcggggagga uuucgacaau      720

agaaugguca accauuuuau ugccgaauuu aaacggaagc acaaaaagga uaucuccgag      780

aauaaacgcg ccgugagacg gcuccgcacc gcuugugaaa gagcgaagcg gacccugagc      840

agcuccacac aggccagcau cgagauugac ucucuuuaug aaggaaucga uuuuuacacg      900

uccauuaccc gcgcuagauu cgaggagcug aacgccgacc ucuuccgggg cacacuggau      960

ccuguugaaa aagcccuuag agacgcuaag cuggauaaga gccagaucca ugacauugug     1020

cucgucgggg gaucuacccg caucccgaaa auccaaaagc ugcugcagga uuucuucaau     1080

ggcaaagagc ucaacaaguc cauuaacccc gacgaagccg uggcguacgg ggcugccguc     1140

caggccgcua uccugagcgg agacaaaucc gagaaugugc aggaucuucu gcuccuggac     1200

guuacaccuc uuucucuggg cauugaaacc gccggcgggg ugaugacggu ccucaucaag     1260

cggaacacaa ccauucccac caagcaaaca cagaccuuua caacguauag cgauaaucag     1320

ccuggagugc ugauccaagu uuacgagggc gagagagcua ugaccaaaga caacaaucug     1380

cucgggaagu ucgaacugac aggaaucccg cccgccccuc gcggcgugcc ccagauugag     1440

gucaccuuug auaucgacgc gaacgggauu cuuaaugugu ccgccgugga uaaaagcaca     1500

ggcaaggaaa acaaaaucac cauuacgaau gacaagggac ggcugucuaa ggaggauauc     1560

gaaagaaugg uucaggaggc ugagaaauau aaggccgaag acgagaaaca gcgcgauaag     1620

gucuccagca aaaacucucu cgaaagcuac gcuuucaaua ugaaggccac cguggaggac     1680

gagaagcugc aaggcaaaau uaacgaugaa gacaagcaga aaauccuuga caagugcaau     1740

gagaucauua acuggcugga uaaaaaucag acagcggaaa aggaggaauu ugagcaccag     1800

caaaaagagc ucgaaaaggu guguaacccu aucauuacca agcuguauca guccgccggg     1860

ggaaugcccg gcgggaugcc cggaggcuuc ccugggggcg gagcuccgcc cucuggcggg     1920

gccagcuccg gaccuacaau cgaggaaguc gacugaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  1904
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt5)

<400>  1904
gggagaaagc uuaccaugau cagcgccucc agagcugccg cggcucggcu ggugggcgcc       60

gccgcuucuc gcgggcccac cgccgcuaga caccaggaca gcuggaacgg acucucccau      120

gaggccuucc ggcuggucuc ucgcagagau uacgcgagcg aagccauuaa gggcgcuguu      180

guggggaucg accuuggaac aacgaauagc ugcguggccg ucauggaggg caaacaagcu      240

aaggugcugg aaaacgccga gggggcgcgg accacaccuu cuguuguggc cuuuaccgcu      300

gauggagaac gccucgucgg caugccggcc aaaagacagg cugugacaaa ucccaacaau      360

accuucuaug ccacaaagcg gcugauuggc cgcagauacg acgauccuga gguucagaaa      420

gacaucaaga acgugcccuu uaagauuguc cgggccagca auggggaugc uuggguggag      480

gcgcacggaa aacuuuauuc cccuagccag aucggcgccu ucgugcugau gaagaugaaa      540

gaaaccgcug agaacuaccu cgggcauacg gccaagaaug ccgucaucac cguucccgcu      600

uauuuuaacg acucucaacg ccaggccaca aaagaugcgg gacagauuuc cggccugaau      660

gugcugagag ugaucaacga accuaccgcu gccgcccucg cuuacgggcu ggacaagagc      720

gaggauaagg ucauugccgu guaugaccuu ggaggcggca cauucgauau cucuauucug      780

gagauccaga aagggguuuu ugaagugaag uccaccaaug gagacacguu ccucggcggg      840

gaggacuuug aucaagcucu gcuucggcac auugucaaag aguucaagcg cgaaacagga      900

guggaccuga ccaaagauaa cauggcccuc cagagaguuc gggaagcggc cgagaaggcu      960

aaaugugagc uguccucuuc cgugcagaca gacaucaauc ugccguaccu caccauggau     1020

agcuccggcc ccaagcaucu gaacaugaaa cuuaccagag cccaguuuga agggaucguc     1080

acagaccuga uucgccggac gaucgcuccu ugccaaaagg ccaugcagga ugcggaggug     1140

ucuaagagcg acauuggaga agucauccuc gugggcggca ugaccagaau gcccaaaguu     1200

cagcaaacag ugcaggaucu guucgggcgc gccccuucca aggcugucaa ccccgacgag     1260

gccguggcua uuggagccgc cauccagggc gggguucuug cuggagaugu gaccgacguc     1320

cugcuccugg acgugacacc gcugagccuc ggcaucgaaa cccugggcgg cguguuuacg     1380

aaacuuauua aucggaacac aaccaucccu accaagaagu cucagguuuu cuccacagcg     1440

gccgauggac aaacccaggu cgagauuaaa gugugucagg gcgagagaga aauggcuggg     1500

gacaauaagc ugcucggaca guucacacug aucggcauuc ccccugcucc ccgcggggug     1560

ccccaaaucg aggucacguu ugauaucgac gccaacggaa uugugcacgu uagcgccaaa     1620

gauaagggca ccgggcggga acagcagauc gugauucagu cuagcggcgg acuuuccaaa     1680

gacgauaucg agaauauggu caagaacgcc gaaaaguacg cggaggagga cagacgcaaa     1740

aaggaacggg uggaggcugu uaauauggcc gaaggcauua uccacgauac agagaccaaa     1800

auggaggagu ucaaggacca acugccugcc gaugaaugca acaaacucaa ggaagagauu     1860

ucuaagauga gagaacugcu ggcucgcaaa gacagcgaga caggggagaa uauccggcag     1920

gccgcgucca gccuccagca ggcuucucug aaacuuuuug aaauggccua uaagaagaug     1980

gccuccgaga gagaaggaag cgggucuucc gggaccggag agcaaaaaga agaucagaag     2040

gaggagaaac agugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  1905
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt5)

<400>  1905
gggagaaagc uuaccauggc cgacaaggag gcuggcggga gcgauggacc cagagaaacc       60

gccccuacau ccgcguacuc uagcccggcu cggucccugg gcgacacggg gaucacaccc      120

cucucuccua gccacauugu gaacgauacc gacuccaaug ucucugagca gcagagcuuc      180

cugguugugg uggccgucga uuuuggaacc acauccagcg gcuaugccua cucuuucacc      240

aaagaacccg agugcaucca ugugaugcgc agaugggaag ggggagaccc uggcguuucc      300

aaccaaaaga cacccaccac gauucuucug accccugagc ggaaauuuca cagcuucggc      360

uaugcugccc gcgauuuuua ccaugaccuc gauccgaaug aggcuaagca guggcuguau      420

cuugaaaaau ucaagaugaa gcugcacaca accggggacc ucacaaugga uaccgaccug      480

acggccgcga acggcaaaaa ggugaaagcc cuggagaucu uugcuuacgc ccuccaguau      540

uucaaggaac aagcucugaa agagcuuucu gaucaggccg gauccgaguu ugaaaauagc      600

gacgucagau gggugauuac aguucccgcg aucuggaagc agccugccaa gcaguucaug      660

cggcaagcug ccuaccaggc ugggcuggcc ucucccgaga acuccgaaca gcucaucauu      720

gcccuggagc cugaagcugc gagcaucuac ugucgcaaac uuagacugca ucagaugauu      780

gagcucuccu cuaaggccgc ugugaaugga uauagcggcu ccgacaccgu cggggccgga      840

uuuacacaag ccaaagagca cauccggcgc aacagacaga gccggaccuu ccugguggaa      900

aaugugauug gcgagaucug gucugaacug gaggaaggcg auaaguacgu cguuguggac      960

uccgggggag gcaccgugga ucucacaguc caccagauuc gccugcccga ggggcaucuu     1020

aaagagcugu auaaggcuac gggaggcccg uacgggagcc ucggagugga cuaugaauuu     1080

gagaaacugc uuuacaagau cuucggcgaa gauuucaucg agcaauuuaa gauuaaaaga     1140

ccugccgcgu ggguugaccu gaugaucgcu uucgaaucuc ggaagcgcgc cgccgcuccc     1200

gauagaacca acccucucaa uauuacacug cccuuuagcu ucaucgacua uuacaaaaag     1260

uuucggggcc acuccgugga gcaugcccug agaaaaucua acgucgauuu cgugaagugg     1320

agcucccagg ggaugcuccg caugagcccc gacgcuauga augcccuguu uaagccuacc     1380

auugauucua ucaucgagca ccuucgggac cuguuccaga aaccggaagu uuccacagug     1440

aaguuucucu uccuggucgg aggcuuugcg gaggcucccc uucugcagca agccgugcag     1500

gccgcuuucg gggaccagug cagaauuauc auuccucagg augucggacu caccauccug     1560

aaaggcgccg ugcuguuugg gcucgacccc gcgguuauua aggugcgccg gagcccucug     1620

acguacggcg ucggagugcu uaacagauau guugaaggca aacauccccc ggagaagcug     1680

cucgugaagg augggacacg cugguguacc gacgucuucg auaaauucau cucugccgac     1740

caauccgugg cucugggaga gcuggugaag cggagcuaca ccccugccaa acccucccag     1800

cuuguuaucg ucauuaauau cuauucuagc gaacacgaua acguguccuu uauuacagac     1860

ccuggcguga agaaaugcgg gacccucaga cuggaucuga caggaacguc uggcaccgcu     1920

guccccgccc gccgggagau ccagacacuc augcaguucg gggacaccga aauuaaggcc     1980

acagcuaucg auauugcgac cagcaagucc gugaaaguug gcaucgacuu ucugaacuac     2040

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  1906
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt5)

<400>  1906
gggagaaagc uuaccaugcu ggccgugccc gagaugggcc uccaggggcu guacaucgga       60

agcuccccug aaagaucucc gguccccagc ccucccggcu ccccucggac ccaagagucu      120

ugcgggauug cuccccuuac accuagccag uccccgaagc ccgaaguucg cgccccucag      180

caggcgucuu ucagcguggu ggucgcuauc gacuuuggaa cgaccuccag cggcuaugcc      240

uucucuuuug ccuccgaucc cgaggcuauu cacaugauga gaaaauggga agggggagac      300

ccuggcgugg cccaucaaaa gacacccacc ugucugcucc ugacaccgga gggcgcuuuc      360

cacagcuuug gguacaccgc ccgggauuau uaccaugacc uugauccuga ggaagcgcgc      420

gacuggcugu auuucgagaa auuuaagaug aaaauccacu cugccacaga ucucacccug      480

aagacgcagc uggaagcugu uaacggaaag accaugcccg cccucgaggu guucgcucau      540

gcccugagau uuuuccggga gcacgcgcuu caggaacugc gcgagcaguc cccuagccuc      600

cccgaaaaag acacagucag augggugcug accguucccg ccauuuggaa gcaaccugcu      660

aaacaguuua ugcgggaggc cgcuuaccuu gccggccugg ugucucgcga aaaugccgag      720

cagcuccuga ucgcucugga gccggaagcg gccuccgucu auugcagaaa gcuccggcug      780

caccagcuuc uggaucucag cgggcgcgcu cccggaggcg ggagacuggg agagcggcgc      840

uccaucgacu cuagcuucag acaagcccgg gaacagcuua gacgcucccg gcauagcaga      900

acauuucugg uggagucugg cgugggcgaa cucugggccg agaugcaggc uggggaucgc      960

uacgucguug ccgacugugg aggcgggacc guggaucuga cggugcacca acuggagcag     1020

ccucauggaa cacucaaaga acuguacaag gcguccggcg ggcccuaugg agcugucggc     1080

guggaccuug ccuucgagca gcugcucugc cggauuuucg gcgaagacuu uaucgccacc     1140

uucaagagac agcgcccugc ugccuggguu gaucugacaa uugcuuuuga ggcccggaaa     1200

agaaccgcgg ggccccaccg cgccggagcu cuuaacauca gccugccguu cucuuuuauu     1260

gacuucuacc ggaagcaaag aggccacaau guggaaaccg cccuccgccg gagcuccguc     1320

aacuuuguga aauggucuag ccaggggaug cugagaaugu ccugugaggc uaugaaugag     1380

cuguuccagc cuacaguuag cggaaucauu cagcauaucg aagcccuccu ggcgcggccc     1440

gaggugcaag gcgucaaacu ucuguuucuc gucgggggcu ucgccgaauc ugcugugcug     1500

cagcacgccg ugcaggcugc ccugggagcc cgcggccuua gaguuguggu cccucaugau     1560

guggggcuca cgauccugaa gggagcuguu cuguuuggcc aggcgcccgg ggugguccgg     1620

gugagacgcu ccccucucac cuauggagug ggcguucuga accgguucgu ccccgggaga     1680

cacccgccug agaaacuucu ggugcgcgac ggcagacggu ggugcacaga uguguuugag     1740

cgcuucgucg ccgcugaaca aagcguggcc cucggagagg aaguuagacg gucuuacugu     1800

cccgcccgcc ccggccagag acgggugcug auuaaucugu auugcugugc ugccgaggac     1860

gcgcgcuuca ucaccgaucc uggggucaga aagugcggag cucuuucccu cgaacuggag     1920

ccggccgacu guggccagga uacagccggg gcucccccug gacggcgcga gauuagagcc     1980

gcgaugcagu uuggcgacac cgaaaucaag gugacggcug uugaugugag cacaaaccgg     2040

uccgucagag ccucuauuga cuuccugagc aauugaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  1907
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt5)

<400>  1907
gggagaaagc uuaccauggc cagagagaug accauccugg gcagcgcugu gcucacacug       60

cuucuggccg gguaccucgc gcagcaauau cugccccuuc cuacgccgaa ggucauugga      120

aucgaccugg gcaccacaua cugcuccguu gggguguucu uucccggaac cggcaaagug      180

aaggucauuc cugaugaaaa cgggcacauc ucuauuccca gcaugguguc cuucacagac      240

aaugauguuu augugggaua cgagucuguc gaacucgcug acagcaaccc ucagaauacc      300

aucuaugaug ccaaacgguu uaucggcaag auuuucacag ccgaggaacu ggaggcugag      360

aucggccgcu accccuuuaa agugcugaac aagaauggga ugguugaguu cuccgugacc      420

ucuaacgaaa cgauuaccgu cagcccugaa uaugugggau ccagacuccu gcuuaagcug      480

aaagagaugg ccgaggcuua ccucggcaug ccgguggcca augcggucau cagcguuccc      540

gccgaauuug accugaagca gcggaacucu acaauugagg cugccaaucu ugcugggcug      600

aaaauccucc gcgugauuaa cgaaccuacc gccgcggcca uggcuuacgg acugcauaag      660

gccgaugugu uccacguccu ggugaucgac cucggcgggg gaacacugga uguuucccuu      720

cugaauaaac agggcggcau guuucucacc agagcuauga gcgggaacaa uaagcuggga      780

ggccaagacu ucaaccagcg gcuucugcag uaucucuaca agcagaucua ucaaacguac      840

ggguuugugc ccucucgcaa agaggaaauu cauagacugc ggcaggccgu cgagauggug      900

aagcugaauc ucacacugca ccaguccgcc cagcuuagcg uucugcucac cguggaggaa      960

caagaucgca aagagccuca uucuuccgac acagaacugc ccaaggauaa acuuagcucc     1020

gcugacgacc acagagucaa cucuggauuc ggccgggggc ugagcgauaa gaaauccgga     1080

gagagccagg ugcucuuuga aaccgagauc ucucgcaagc uguucgacac ccugaacgag     1140

gaucucuucc agaagauucu ggucccgauc caacaggugc uuaaagaagg ccaccuggag     1200

aagacagaaa uugacgaggu ugugcucguc ggcgggucca cgagaauccc ucggauccgc     1260

caggugauuc aggaauuuuu cggaaaagau cccaauacca gcguugaccc ugaucuggcg     1320

guggucacag gcguggccau ccaagcuggg auugacggag gcucuuggcc ccuucaggug     1380

agcgcccugg agauccccaa caagcaucuc cagaaaacca auuuuaacug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  1908
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt5)

<400>  1908
gggagaaagc uuaccauggc cgcuaucggc guccaccugg ggugcaccag cgccuguguc       60

gcgguuuaca aggacggcag agcuggagug guggccaacg augccgggga ccgggucaca      120

cccgcugugg uugccuauuc cgagaaugaa gagauugugg gacucgcugc caaacagucu      180

cgcaucagaa acauuagcaa uacggucaug aaggugaaac aaauccuggg ccgguccucu      240

agcgauccuc aggcgcagaa guacauugcc gaauccaaau gccuuguuau cgagaagaac      300

gggaagcugc gcuaugaaau cgacaccgga gaggagacaa aauucgugaa uccggaagau      360

gucgcuagac ucaucuuuuc uaagaugaaa gagaccgccc auagcgugcu gggcuccgac      420

gcuaacgaug uggucauuac aguucccuuc gacuuuggcg aaaagcagaa aaaugcccuu      480

ggggaggcgg cccgggcugc cggauucaac gugcugcgcc ucauucacga gccuagcgcu      540

gcccugcugg ccuacggcau cgggcaagau ucucccaccg gaaaguccaa uauucucgug      600

uuuaagcugg gcgggacaag ccuuucucug uccgucaugg aagugaacag cggaaucuau      660

agaguucucu cuaccaauac ggacgauaac auuggcggcg cucauuucac cgagacacug      720

gcgcaguacc uugccuccga auuucagcgg agcuucaaac acgacgugcg cgggaaugcu      780

agagccauga ugaagcugac caacuccgcc gaggucgcua aacauucucu cagcacacug      840

ggauccgcca auuguuuucu ggauagccuc uaugaaggcc aggacuucga cugcaacgug      900

ucucgggcgc gcuuugagcu gcuuuguucc ccucuguuca acaagugcau cgaggcuauc      960

agagggcucc uggaucaaaa uggauuuacc gccgacgaua uuaacaaagu ugugcuuugu     1020

ggcgggagcu cucggauccc caagcugcag cagcucauua aagaccuguu cccugccguc     1080

gaacugcuca auagcauccc gcccgaugag gugauuccua ucggagcugc caucgaagcu     1140

ggcauucuga ucggcaagga gaaccuucug gucgaagacu cccucaugau ugagugcucu     1200

gcccgcgaua uccuggugaa ggggguugac gagagcggag cguccagauu cacggugcuu     1260

uuucccagcg gcacaccucu gcccgcccgg agacagcaca cccuccaagc uccggggucu     1320

auuuccagcg ucugucugga acuguacgag ucugauggca aaaauuccgc caaggaagag     1380

acaaaauucg cucagguggu ucuccaggac cuggauaaga aagaaaacgg acuucgcgac     1440

auccuggccg ugcucaccau gaagcgggac gggagccugc acgugaccug cacagaucaa     1500

gagacgggca agugugaggc gaucuccauu gaaaucgccu cuugaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  1909
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt5)

<400>  1909
gggagaaagc uuaccaugag cguggucggc cuggacguug ggucccaguc uugcuacauc       60

gccguggcua gagccggagg cauugagacc aucgcgaacg aauuuagcga ucgguguaca      120

cccuccguga uuucuuuugg gagcaagaau cgcacgaucg gagucgcugc caaaaaccaa      180

cagauuaccc acgccaauaa cacagugucc aauuucaaga gauuucaugg ccgggcuuuc      240

aacgacccuu uuauccagaa agagaaggaa aaucucucuu augaucuggu uccgcuuaaa      300

aacgggggag ugggcaucaa ggucauguac augggcgagg aacaccuguu cagcguggag      360

cagauuaccg ccaugcuccu gacaaaacuu aaagagaccg cugaaaauuc ccugaagaaa      420

cccguuacag acugcgugau cagcgucccu ucuuucuuca ccgaugccga gcgcagaucc      480

gugcucgacg cggcccaaau uguggggcug aacugucugc ggcucaugaa ugauaugacg      540

gcugucgccc ugaacuaugg aaucuacaag caggaccuuc ccagccugga ugaaaaaccu      600

cgcauuguug uguuugugga caugggccau ucugcuuucc aggucuccgc cugcgcguuu      660

aauaagggga agcucaaagu gcugggaacc gccuucgauc ccuuucuugg cgggaagaac      720

uucgacgaga aacugguuga gcacuucugu gcugaauuua agacaaaaua uaagcucgau      780

gccaaaagca agaucagagc ucugcugcgg cucuaccagg agugcgaaaa gcugaaaaag      840

cugaugucuu ccaauagcac cgaccuuccu cucaacauug aguguuucau gaacgacaaa      900

gauguguccg gaaagaugaa ucgcucucaa uuugaggaac ugugcgccga gcuucugcag      960

aaaaucgaag ucccgcucua uagccugcug gagcagacac aucucaaggu ggaagacguu     1020

uccgccgugg agaucgucgg cggcgcuacc cggauucccg cggugaagga aagaaucgcc     1080

aaauucuuug ggaaggauau uagcacgaca cugaacgcug acgaggccgu cgcccgcgga     1140

ugugcccuuc agugcgcuau ccugucuccu gcguucaaag ugagagaguu uuccguuacc     1200

gaugcugugc ccuucccuau uagccucauc uggaaucacg acucugaaga uacagagggc     1260

guccacgaag uguuuagccg gaaccaugcc gcccccuucu ccaagguucu gaccuuucuu     1320

cgcagagggc cguucgagcu ggaggcuuuu uacucugacc cucaaggagu gcccuacccu     1380

gaagccaaaa ucggccgguu cgucgugcag aaugugagcg cucagaagga uggggagaag     1440

uccagaguua aagucaaggu gcgcgugaac acccacggaa uuuucacaau cagcacggcc     1500

ucuauggucg aaaaagugcc caccgaggaa aaugagaugu ccagcgaggc ggacauggaa     1560

ugucucaacc aacggccccc ugagaauccg gauacagaca agaacguuca gcaggacaau     1620

ucugaagccg gcacccagcc ccaagugcag acagaugcuc agcagaccuc ccaaagcccu     1680

cccuccccug agcugacguc ugaagagaac aaaauucccg acgccgauaa ggcuaaugag     1740

aagaaagucg accagccgcc ugaagccaag aaacccaaga ucaaaguggu uaacguggag     1800

cugccuauug aagcgaaucu cgucuggcag cugggcaagg aucuucugaa cauguauauc     1860

gagacagaag ggaaaaugau caugcaggac aagcucgaga aggagagaaa cgaugccaaa     1920

aaugcugugg aagaguacgu uuaugaauuu cgcgacaagc ugugcggacc cuacgagaaa     1980

uucauuugcg aacaagauca ucagaacuuu cugcggcuuc ucaccgagac cgaggacugg     2040

cuguaugaag agggcgaaga ucaggccaag caggcuuacg uggacaaacu ggaggagcuc     2100

augaagaucg ggacaccugu caaggugaga uuccaagaag ccgaggaacg ccccaaaaug     2160

uuugaggaac ugggacagcg gcuucagcac uaugccaaga uugcugcgga uuucagaaau     2220

aaagacgaga aguacaacca caucgacgag agcgaaauga aaaaggugga gaaguccguc     2280

aaugaaguua uggaguggau gaacaaugug augaacgccc aagcuaaaaa gucucuggau     2340

caggacccgg ugguccgcgc ccaggaaauu aaaaccaaga ucaaagagcu caauaacaca     2400

ugugagccug ugguuacgca gcccaagccc aagauugaaa gcccuaaacu ggagcggacc     2460

ccgaauggcc ccaacaucga uaagaaagaa gaggaccugg aagauaagaa uaacuuuggg     2520

gccgagccuc cccaucaaaa uggcgagugc uacccuaacg aaaagaacuc cgugaauaug     2580

gaccuugauu gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  1910
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt5)

<400>  1910
gggagaaagc uuaccauggc cgacaaggug agacggcagc gccccagacg gcgcgucugc       60

ugggcucugg uugccgugcu ccuggcggau cuucuggcuc ucagcgacac ccuggccgug      120

auguccgucg aucuuggcuc ugagagcaug aaaguggcca ucguuaagcc uggggugccg      180

auggaaaucg uccugaacaa agaguccaga cggaagacac ccgugaucgu uacgcucaaa      240

gaaaaugagc gcuucuuugg agacucugcu gccagcaugg cuauuaagaa cccuaaggcc      300

acccugagau acuuccaaca ucugcucggc aaacaggcgg auaaucccca cguggcccug      360

uaucaggcuc gguuuccuga acacgagcuu acauucgacc cccagcgcca aaccguccau      420

uuucagaucu ccucucagcu gcaguucagc ccugaggaag ugcucgggau ggugcugaac      480

uacuccagaa gccuugccga ggauuuugcu gaacaaccga uuaaggacgc cgucaucaca      540

guucccgugu ucuuuaauca ggcggagcgg cgcgccgugc ugcaggcugc cagaauggcu      600

ggacucaaag uccugcagcu gaucaacgau aauaccgcca cagcccucuc uuauggcgug      660

uuccggcgca aggacauuaa caccacggcu caaaauauca uguuuuacga uauggggucc      720

ggaagcaccg uuuguacaau ugugaccuau cagaugguca aaacaaagga ggcgggcaug      780

cagccucaac ugcagaucag aggcgugggg uucgaccgga cccuuggagg ccuggaaaug      840

gagcucagac ugcgcgaacg gcuugccggg cuguuuaacg agcagagaaa gggacagcgc      900

gcuaaagaug uucgggaaaa ucccagagcc auggccaagc uccugcgcga ggcuaaccgg      960

cugaaaacgg ugcucucugc caaugcggac cacauggcuc aaauugaggg ccugauggac     1020

gaugucgacu ucaaggccaa agugacaaga gucgaguucg aggaacuuug cgccgaucug     1080

uuugagcgcg ugccugggcc cguucagcag gcucuccagu ccgccgaaau gagccuggac     1140

gagaucgagc aagugauucu ugucggaggc gcuacccggg ugccgagagu ucaggaagug     1200

cugcucaagg ccgucggcaa agaggaacug gggaagaaca ucaaugcgga ugaggccgcu     1260

gccaugggag cuguguacca ggccgcggcc cugucuaagg cuuucaaagu gaagccuuuu     1320

guuguccgcg acgccguggu guaucccauc cucgucgagu ucacacggga gguggaggaa     1380

gaaccuggca uucauucccu gaaacacaac aagagaguuc uuuuuagccg gauggggccc     1440

uacccccagc gcaaagugau caccuucaac agauacuccc acgauuuuaa uuuccauauu     1500

aacuauggag accugggcuu ucucgggccu gaagaucugc gggucuucgg aucucaaaau     1560

cugaccacag ugaagcucaa gggcguuggc gacagcuuua aaaaguaccc ggauuaugag     1620

uccaaaggga ucaaggcuca cuucaaccuc gacgagagcg gagugcuguc ucuggacaga     1680

gucgaauccg uguuugagac gcucguugaa gauagcgccg aggaagaguc uacccugaca     1740

aaacuuggca auaccauuag cucccuguuc gggggaggca caacccccga cgccaaggag     1800

aacgggacgg auacagugca ggaagaggaa gagucuccug cugaaggcag caaggacgag     1860

cccggagagc aggucgaacu caaagaggaa gcggaggccc cuguggaaga uggcucccag     1920

cccccgccuc ccgagccuaa gggggacgcu acccccgagg gagaaaaagc caccgagaag     1980

gaaaauggcg auaaaagcga ggcccaaaag ccuucugaga aggcugaagc cgggcccgag     2040

ggaguggcgc cggcuccuga aggcgagaaa aagcagaaac ccgcccgcaa gcggagaaug     2100

gucgaagaga ucgggguuga gcugguggug cuggaccuuc ccgaucuccc ugaagacaaa     2160

cuggcccagu ccguccaaaa gcugcaggau cucacacugc gcgaccuuga gaaacaggaa     2220

agagagaagg cugccaacag ccuggaagcg uucaucuuug agacccagga uaagcucuac     2280

caaccggagu aucaggaagu gucuacagag gaacagcggg aggaaauuuc cggcaaacug     2340

agcgcugccu ccacguggcu ggaggacgag ggaguuggcg ccaccacagu gaugcuuaag     2400

gaaaaacucg cugagcugcg caagcugugu caggggcuuu ucuuuagagu cgaagaacgg     2460

aaaaaguggc ccgagcgccu gucugcccuu gacaaucugc ucaaccauag cuccauguuc     2520

cugaagggag cuagacugau cccugaaaug gaucaaauuu uuaccgaggu ggaaaugaca     2580

acccuugaga aaguuaucaa ugaaacgugg gccuggaaga acgcgacccu cgccgagcag     2640

gcuaaacugc ccgccacaga gaagccugug cugcucucua aagacauuga agcuaagaug     2700

auggcccugg aucgggaggu ccaguaccuu cugaauaagg ccaaauucac caagccccgc     2760

ccuagaccca aagacaagaa cggcacacgg gcugaaccgc cucucaaugc gagcgccucc     2820

gaucaggggg agaaagugau ucccccugcu ggacaaaccg aagacgccga gcccaucagc     2880

gagccggaaa agguugagac gggcucugaa ccuggggaua cagagccccu ggaacugggc     2940

ggaccuggcg ccgagcccga gcagaaggaa caguccaccg ggcaaaaacg cccccuuaag     3000

aacgacgagc ugugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1911
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt5)

<400>  1911
gggagaaagc uuaccaugcc cgaggaaacc cagacacaag accagcccau ggaggaagag       60

gaaguggaga cguucgccuu ucaggcugag aucgcccagc ugaugagccu cauuaucaac      120

accuucuacu ccaauaagga aauuuuucug agagagcuua ucucuaacag cuccgaugcg      180

cuggacaaaa uucgguauga aucucucaca gauccgagca agcuggacuc cggcaaagag      240

cuucacauca aucugauccc caacaagcaa gaucgcaccc ucacaauugu cgacaccggg      300

aucggaauga caaaagcuga ucugauuaau aaccugggca ccaucgccaa gucugggacg      360

aaggccuuca uggaggcucu ccaggccgga gcugacauua gcaugaucgg ccaguuuggg      420

guuggauucu acuccgccua ucugguggcg gaaaaaguga ccgucauuac aaagcauaau      480

gaugacgagc aguacgccug ggaaagcucu gcuggcggcu ccuuuaccgu gagaacagau      540

accggggagc cuaugggacg gggcacgaaa guuauccuuc accugaagga agaccaaaca      600

gaguaucucg aggaacgcag aaucaaagag auugugaaga agcauagcca guucaucggg      660

uaccccauua cccuguuugu cgaaaaagag cgggauaagg aagugucuga cgacgaggcc      720

gaggaaaaag aggauaagga agaggaaaaa gagaaggagg aaaaagaguc cgaagacaag      780

ccugagaucg aggauguugg aagcgacgaa gaggaagaga agaaagaugg cgacaagaaa      840

aagaaaaaga agauuaaaga aaaguauauc gaucaggagg agcuuaacaa aacaaagccc      900

aucuggaccc gcaauccuga cgauauuacc aacgaagagu acggggaguu cuacaaaucu      960

cugacaaaug acugggagga ucaccucgcu gugaagcauu uuuccgucga aggacagcug     1020

gaguucagag cccugcucuu ugugccgcgg cgcgcgcccu ucgaccuguu cgagaacaga     1080

aagaaaaaga auaacaucaa acuuuaugug cggcgcgucu uuauuaugga caauugcgaa     1140

gaacugaucc cugaauaccu caacuucauu agaggcguug uggauagcga ggaccugccc     1200

cuuaacaucu cccgggaaau gcugcaacag ucuaagaucc ucaaagugau ucgcaagaau     1260

cuggucaaga aaugucugga gcucuuuacg gagcuggccg aagauaagga gaacuauaaa     1320

aaguucuacg aacaguuuag caaaaauauc aaacuuggca uucacgagga cucccaaaac     1380

agaaagaagc ugagcgagcu ccugcgguau uacaccucug cuuccgggga ugaaauggug     1440

agccuuaagg acuauugcac aagaaugaaa gagaaucaga agcacaucua cuacauuacc     1500

ggagaaacaa aagaucaggu ugccaacucu gcuuucgugg agcgccugcg gaagcauggc     1560

cucgaaguca ucuauaugau ugagccuauc gacgaguacu gugugcagca acugaaagaa     1620

uuugagggga agacccuggu uagcgugacg aaggaaggac ucgagcugcc cgaagaugag     1680

gaggagaaaa agaaacagga agaaaagaaa acaaaguucg agaaucuuug caagaucaug     1740

aaagacauuc uggaaaagaa agucgagaag guggucgugu ccaacagacu cguuaccucu     1800

ccguguugca ucgugaccag cacauauggc uggaccgcca auauggagcg cauuaugaaa     1860

gcccaggcuc ugcgggauaa cuccacaaug ggguacaugg cggccaagaa gcaccuggaa     1920

aucaauccug accauagcau uaucgagacg cuuagacaga aagcugaagc cgauaagaac     1980

gacaaaucug ucaaggaccu cgugauccug cuguaugaga ccgcccuccu guccagcgga     2040

uuuucucuug aggaucccca aacacacgcu aaucgcauuu accggaugau caaacugggc     2100

cucggcauug acgaagauga cccuaccgcc gaugacacau ccgcggcugu uaccgaggaa     2160

augccucccc uggaggggga ugacgauacg agcagaaugg aagaggugga cugaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  1912
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt5)

<400>  1912
gggagaaagc uuaccaugga cagcuccaag cuggauucug gcaaagggcu ccacaucaac       60

cuggugccca auaagcagaa ccaaacccuu acaauugucg acacgagaau cggaaugacc      120

aaaacagauc ugauuaauaa ccucggcacc guuacaaaga gcgggaccaa agccuucaug      180

gaggcucugc aggccgacgc ggauaucucc augauuggac auuuuggcgu gggguucuac      240

ucugcuuauc uuguggccaa gaaggucaca gugaucagca aacacaauaa cgacgaacag      300

uacaccuggg aguccucugc cggaggcagc uuuacgguuc ggaccgauga augaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  1913
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt5)

<400>  1913
gggagaaagc uuaccaugcc cgaggaagug caccauggcg aggaagaggu cgaaaccuuc       60

gccuuucagg cugagaucgc ccaacugaug agccucauua ucaacacauu cuacuccaau      120

aaggagauuu uucugagaga acuuaucucu aacgcgagcg acgcucugga uaaaauucgg      180

uaugaguccc ucacggaccc uucuaagcug gauagcggga aagaacuuaa gaucgacauc      240

auuccgaauc cccaggagcg cacccugaca cucguugaua ccggaaucgg caugacaaaa      300

gccgaccuga uuaacaaucu ggggaccauc gccaaguccg gaacaaaggc uuucauggag      360

gcccuccagg cuggcgccga uauuucuaug aucgggcagu uuggaguggg cuucuacagc      420

gcguaucugg uggccgaaaa agucgugguu auuaccaagc acaacgacga ugagcaauac      480

gcuugggaau ccagcgccgg cgggucuuuu acggugagag cugaccaugg agagccuauc      540

ggccggggga ccaaagucau ccuucaccug aaggaagauc agacagagua ucucgaggaa      600

cgcagaguga aagagguugu gaagaagcau ucccaguuca uuggauaccc caucacccug      660

uaucuugaaa aagagcggga aaaggagauu agcgacgaug aggccgaaga ggaaaaaggc      720

gagaaggaag aggaggacaa agacgaugaa gagaagccua aaaucgaaga cgucgggucu      780

gaugaggagg acgauuccgg aaaggacaag aaaaagaaaa caaagaaaau uaaggaaaag      840

uacaucgauc aggaggaacu gaauaaaacc aagcccaucu ggacgcgcaa cccugacgau      900

auuacacaag aggaauacgg cgaguuuuau aaaagccuca ccaaugacug ggaggaucac      960

cuggcgguga agcacuucuc uguggaaggc cagcuggagu uuagagcccu ccuguucauc     1020

ccgcggcgcg cucccuuuga ccuuuucgaa aacaaaaaga agaaaaauaa cauuaagcug     1080

uacgucagac ggguuuucau cauggacucc ugcgaugagc ucauuccuga auaucugaau     1140

uuuauccgcg ggguggugga cagcgaggau cuuccccuga acaucuccag agagaugcuc     1200

cagcagucua aaauucugaa ggucauccgg aaaaauauug ugaagaagug ucuggaacuc     1260

uucagcgagc uggccgaaga caaagagaac uacaagaaau uuuaugaggc uuucuccaag     1320

aaccuuaaac ugggaaucca ugaggauagc acaaaucgca gacggcucuc ugagcugcuu     1380

agauaccaca ccucccaaag cggcgacgaa augaccucuc ugagcgagua uguuucccgc     1440

augaaggaaa cacagaaauc uauuuacuac aucacggggg agagcaagga acagguggcc     1500

aacuccgccu uugucgaacg ggugagaaag cgcggauucg agguugugua uaugaccgaa     1560

ccuauugaug aguacugcgu ccaacagcuc aaagaauuug acggcaagag ccuggugucu     1620

gucacaaaag aggggcugga gcuccccgaa gaugaggaag agaagaaaaa gauggaagag     1680

uccaaggcua aauucgagaa ucuguguaaa cuuaugaagg aaauccugga caagaaagug     1740

gagaagguua ccaucagcaa ccggcucgug ucuuccccgu gcuguauugu cacaagcacc     1800

uauggaugga cggcgaauau ggaaagaauc augaaggccc aggcucugcg cgauaacucc     1860

acaaugggcu acaugauggc caaaaagcau cuggagauua auccugacca ccccaucgug     1920

gaaacccuuc ggcagaaagc cgaggcugau aagaacgaca aagccguuaa ggaccucgug     1980

guccugcugu uugagaccgc gcuccugucu agcggcuucu cccuugaaga uccucaaaca     2040

cacucuaaua gaauuuaucg caugaucaag cuggggcucg gaaucgacga ggaugaagug     2100

gcugccgagg agcccaacgc cgcugugccc gacgaaauuc cuccgcugga gggcgaugaa     2160

gacgccagcc ggauggagga aguugauuga ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  1914
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt5)

<400>  1914
gggagaaagc uuaccaugag agcccugugg gugcucggcc ugugcugugu ccuucugacc       60

uucgggagcg uucgggcuga cgaugaggug gacguggaug gaacagucga agaggaccuc      120

ggcaaguccc gcgaaggguc uagaacggau gacgaggugg uucagcggga agaggaggcc      180

auccaacugg auggacuuaa cgcgagccag auucgcgaac ugagagagaa auccgaaaag      240

uuugcuuucc aggccgaggu gaaucggaug augaaacuca ucauuaacuc ucuguacaag      300

aauaaagaga ucuuucugcg cgaacucauu agcaacgccu ccgacgcucu ggauaagauc      360

agacuuaucu cucugaccga cgagaaugcc cucagcggca acgaagaacu gacagucaag      420

auuaaaugcg auaaggagaa aaaucuucug cacgugaccg acacaggggu uggaaugacc      480

cgggaggagc ucgugaagaa ccugggcaca aucgcuaaau ccggcaccag cgaguuccug      540

aauaagauga cggaggccca ggaagauggg caaucuaccu ccgagcucau uggacaguuu      600

ggcgucgggu ucuauagcgc guuucuggug gccgacaagg ugaucgucac aucuaaacau      660

aacaaugaca cccagcacau uugggaaucc gauagcaacg aguucucugu uaucgcugac      720

ccccgcggaa auacacuugg cagagggacc acgauuacac uggugcucaa ggaggaagcc      780

uccgauuacc uggagcuuga caccaucaaa aaccugguga agaaauauag ccaguuuauc      840

aauuucccua uuuacgucug guccucuaag acagaaaccg uggaggaacc gauggaggag      900

gaagaggcug ccaaagaaga gaaggaggaa agcgaugacg aggcggccgu ugaagaggaa      960

gaggaggaaa agaaacccaa gaccaaaaag guggagaaaa cagucuggga uugggaacuc     1020

augaacgaca ucaagccuau uuggcaacgg cccuccaagg agguggaaga ggaugaguau     1080

aaagccuuuu acaagagcuu cucuaaagaa uccgacgauc cuauggcuua uauccauuuu     1140

acggcugagg gagaaguuac cuucaagagc auucuguucg ugcccacauc ugccccucgc     1200

ggccuguuug acgaguacgg cagcaaaaag uccgacuaca ucaagcucua ugucagacgg     1260

guguucauca ccgaugacuu ucacgauaug augccgaaau accugaacuu cgucaagggg     1320

gugguugacu cugaugaccu uccccugaau gugagccgcg aaacacucca gcagcauaaa     1380

cugcuuaagg ucauucggaa aaagcuggug agaaagaccc ucgauaugau caaaaagauu     1440

gccgacgaua aauauaacga cacguuuugg aaggaguucg gaacaaauau caaacugggc     1500

guuauugagg aucacuccaa cagaacccgc cuggcuaagc uccugcgguu ucagagcucu     1560

caccauccua ccgacaucac aucccuugau caauacgugg aaagaaugaa agagaagcag     1620

gacaagaucu auuucauggc ggggagcucu cgcaaagaag ccgaguccag ccccuuuguc     1680

gagcggcugc ucaagaaagg auacgaagug auuuaucuga ccgagccugu ggacgaauac     1740

uguauccagg cucugcccga guucgauggc aagagauuuc aaaauguugc caaagaaggg     1800

gucaaguucg acgaguccga gaagacaaaa gaaucucgcg aggccgugga aaaggaguuu     1860

gaaccgcuuc ucaacuggau gaaagauaag gcucugaaag acaagauuga gaaggccgug     1920

gucagccagc ggcugacgga guccccuugc gcgcucgugg cuucucagua cggauggagc     1980

ggcaauaugg aaagaaucau gaaagcccag gccuaucaaa ccggcaagga uauuuccaca     2040

aacuacuaug cuagccagaa aaagaccuuc gagaucaauc cccgccaccc ucugauucgg     2100

gacaugcuua gacgcaucaa agaagaugag gacgauaaga caguucugga ccucgccgug     2160

guccuguucg aaaccgcuac gcugcggucu ggguaccuuc uccccgauac caaggccuau     2220

ggagacagaa ucgagcggau gcugcgccug ucccucaaca uugaucccga cgcgaaagug     2280

gaggaagaac cugaagagga gccggaagag acagccgaag acaccacaga ggauaccgaa     2340

caggacgagg augaggaaau ggacguuggc acggaugagg aagaggaaac agcuaaggag     2400

agcaccgccg agaaagacga acugugagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  1915
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt5)

<400>  1915
gggagaaagc uuaccauggc cagagagcug cgggcucucc ugcuuugggg ccgcagacug       60

cggccccucc ugcgcgcccc ugcgcuugcu gccgugcccg ggggaaagcc gauccugugc      120

ccuagacgga ccacagccca gcucggcccc cgcagaaacc cugcuuggag ccugcaagcc      180

gggcggcugu ucuccacgca gaccgcugaa gacaaagagg aaccccucca cucuauuauc      240

agcuccacag agucugucca gggaagcacc uccaagcaug aauuucaggc cgagacaaag      300

aagcugcuug auauuguugc gcgcucucug uacagcgaga aagaaguguu caucagagag      360

cucauuucca augccagcga cgcucuggaa aaacuucggc acaagcuggu gucugauggc      420

caagcccucc cugagaugga gauccaucug cagaccaacg cugaaaaagg gacaaucacc      480

auucaggaca cgggaaucgg caugacccag gaggaacugg ucuccaaucu cggcacaauu      540

gcccgcagcg ggucuaaggc guuucuggau gcccuucaaa accaggcuga ggccuccagc      600

aaaaucauug gacaguucgg cgugggguuu uauucugcuu ucaugguugc cgacagagug      660

gaagucuacu cccggagcgc cgcuccggga ucccugggcu aucaguggcu cucugauggg      720

agcggagugu uugagaucgc ggaggccucc ggcguucgca ccggcacaaa gauuaucauc      780

caccugaaaa gcgacuguaa ggaguucucu uccgaggcua gagugcggga ugucgugacc      840

aaguacagca auuuuguguc uuucccccuu uaucugaacg ggagacgcau gaauacgcuc      900

caagccauuu ggaugaugga cccuaaagau guccgggaau ggcagcauga ggaauuuuac      960

agauauguug cccaggcuca cgacaagccc cgcuacacac ugcacuacaa aaccgaugcc     1020

ccucugaaca uccggagcau uuucuaugug cccgacauga agccguccau guuugacgug     1080

ucuagagagc ucggaagcuc cgucgcgcug uacagccgca aagugcuuau ccaaacaaag     1140

gcuaccgaua uucugccuaa auggcuccgg uucaucagag gcguugugga cucugaggau     1200

aucccccuga aucuuucccg cgaacugcuc caggagagcg cccugauucg gaagcugaga     1260

gacguccucc agcagcgccu gaucaaguuc uuuauugauc aaucuaaaaa ggacgccgaa     1320

aaauaugcua aguucuuuga ggauuacggg cuuuucaugc gggaaggaau cgugaccgcc     1380

acagagcagg agguuaaaga agacauugcu aagcugcuca gauaugaguc cagcgcccug     1440

ccuuccggcc agcugacguc ucuuagcgaa uacgcguccc ggaugcgcgc cgggaccaga     1500

aacaucuauu accucugcgc ucccaaucgg caucuggccg agcacucucc cuacuaugag     1560

gcuaugaaga aaaaggauac agaagugcug uuuuguuucg agcaguuuga cgaacucacc     1620

cugcuucauc ugagagaguu cgauaaaaag aaacucauca gcgucgaaac agacauugug     1680

gucgaccacu acaaggagga gaaguuugaa gaucgcuccc cugccgcgga gugccugagc     1740

gaaaaagaga ccgaagaacu gauggccugg augcggaacg ugcuuggauc uagaguuacg     1800

aaugugaagg ucacacuccg ccuggacacc cacccggcua uggugaccgu ucuggagaug     1860

ggcgccgcua gacauuuccu ccggaugcaa cagcuggcca aaacacagga ggaacgcgcc     1920

cagcuucugc aacccacccu cgaaaucaac ccuagacacg cucugauuaa gaaacugaau     1980

cagcuucggg cguccgagcc cggccucgcc cagcugcugg uggaucagau cuaugaaaac     2040

gcuaugauug ccgccgggcu cgucgacgau ccucgcgcua uggugggaag acugaacgag     2100

cuucugguga aggcccucga gcggcauuga ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  1916
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt5)

<400>  1916
gggagaaagc uuaccauggg caagaucagc ucccugccca cccagcuuuu caaaugcugu       60

uuuugcgacu uccugaaggu gaaaaugcac acaaugucua gcucccaucu cuuuuaccug      120

gcccucuguc ugcuuacguu caccucuagc gcuacagccg ggccugagac ccugugcgga      180

gcggaacucg ucgaugcucu gcaauuuguu uguggcgaca gaggguucua uuuuaacaag      240

ccgacaggau acggcuccuc uagccggcgc gcuccccaga ccgggauugu ggaugagugc      300

uguuucagau ccugcgaccu gcggcgccuc gaaauguauu gugccccucu gaaacccgcc      360

aagagcgcca gaucugugcg ggcucagcgc cacacagaua ugccuaagac ccagaaagag      420

guccaucuua agaaugccuc cagaggaagc gcgggcaaca aaaauuaccg gaugugagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  1917
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt5)

<400>  1917
gggagaaagc uuaccauggg cauccccaug ggaaagagca ugcuggugcu ccugaccuuc       60

cuugccuuug cuuccugcug uauugccgcg uacagaccuu cugagacacu gugcgggggc      120

gaacucgucg acacgcugca guucguuugu ggggaucggg gauuuuauuu cagccgcccg      180

gcuuccagag ugucucggcg cagcagaggc aucguggagg aaugcuguuu ucgguccugc      240

gaccuugccc ugcucgagac cuacugugcc acacccgcua aaucugaacg cgaugucagc      300

accccuccca cagugcugcc ugacaacuuc cccagauauc cuguugggaa guuuuuccaa      360

uacgauaccu ggaaacaguc cacacagcgg cugcgcagag gacucccggc ccugcuucgg      420

gcucgcagag gccacgugcu ggccaaggag cucgaggcgu uucgggaagc caaacgccau      480

agaccccuga uugcccuucc uacccaggac cccgcucacg gcggggcucc ucccgagaug      540

gccagcaauc ggaagugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  1918
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt5)

<400>  1918
gggagaaagc uuaccaugaa cagcuucucc accucugccu uuggccccgu ggcuuucagc       60

cuggggcucc ugcuuguccu gccugccgcg uuuccggcuc ccguuccucc cggagaggac      120

uccaaggaug uggccgcccc ucacagacag ccccucacau cuagcgaacg gaucgacaaa      180

caaauucgcu acauccugga uggcauuucc gcucuuagaa aggagacgug caauaaaucu      240

aacaugugug aaagcuccaa ggaggcccug gcugaaaaua accucaaucu gccuaaaaug      300

gccgagaagg acgggugcuu ccagagcgga uuuaacgagg aaaccugucu ggugaagauc      360

auuacaggcc uccuggaguu cgaagucuau cuugaguacc ugcagaaucg guuugagucu      420

uccgaagaac aggcgcgcgc cgugcaaaug agcaccaaag uucucaucca guuccugcag      480

aagaaagcua agaaccuuga ugccaucaca accccggacc ccacaaccaa ugcuucucug      540

cucacgaaac ugcaggccca aaaccagugg cugcaggaua ugaccacaca ucucauucug      600

agauccuuua aggaguuccu ucagagcucu cugcgggcgc uccgccaaau gugaggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  1919
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt5)

<400>  1919
gggagaaagc uuaccaugcc ccugcucugg cugagaggcu uccuucuggc cagcugcugg       60

aucauugugc gguccucucc uaccccgggg agcgagggac acuccgcugc ccccgacugu      120

ccuucuugcg cgcucgcugc ccugcccaag gaugucccua acagccagcc cgaaaugguu      180

gaggccguga aaaagcauau ccuuaauaug cugcaccuca aaaagcgccc ugacgugaca      240

caaccggucc ccaaagcugc ccugcugaac gcuauuagaa agcuccaugu gggcaagguu      300

ggggaaaaug gauacgugga gaucgaagau gacauuggcc ggcgcgccga gaugaacgag      360

cugauggaac agacguccga gaucaucacc uuugcggaau cugggacagc cagaaaaacc      420

cuucacuucg agauuagcaa ggagggaucc gaucugagcg ucguggaacg ggcugagguu      480

uggcucuuuc ugaaagugcc uaaggccaau cgcacaagaa ccaaagucac aauccggcuu      540

uuccagcagc aaaagcaucc ccagggcucu cuggacaccg gcgaagaggc ugaagaggug      600

gggcucaagg gagagcgcuc cgaacugcug cucagcgaga aaguggucga ugccagaaag      660

ucuacguggc acguuuuucc uguguccagc ucuauucagc ggcugcuuga ccagggcaaa      720

uccagccugg augugcgcau cgcgugugaa caaugccagg aguccggggc cucucucguc      780

cugcuuggaa agaaaaagaa aaaggaagag gagggcgaag ggaagaaaaa gggaggcggc      840

gaagggggag cuggcgccga cgaggagaaa gaacagagcc acagacccuu ccugaugcuc      900

caggcucggc aauccgagga ucauccgcac cgcagacgga gacgcgggcu ggagugugac      960

ggaaagguga acauuugcug uaaaaagcag uuuuucguua gcuuuaagga uaucggcugg     1020

aaugacugga uuaucgcccc uucuggguau caugccaacu acugcgaagg agaguguccc     1080

ucccacaucg cuggcaccag cggcucuagc cuguccuucc acucuacagu gauuaaucau     1140

uaucggauga gagggcacag cccuuuugcg aaccucaaau ccugcugugu ccccaccaag     1200

cugcgcccca ugagcaugcu uuacuaugac gauggacaga auaucauuaa aaaggacauc     1260

caaaacauga uuguggaaga gugcggcugc ucuugaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  1920
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt5)

<400>  1920
gggagaaagc uuaccaugga cggccugccc gggagagccc ucggagcugc cugccugcuu       60

cugcucgcgg cuggcuggcu ggggccugag gccuggggaa gcccgacacc cccucccacc      120

ccugccgcuc ccccuccgcc cccucccccu ggcucccccg ggggaucuca ggauacgugu      180

accagcugcg gcggcuuccg gcgcccggag gaacuuggga gaguggacgg agauuuucug      240

gaagccguca agcggcacau ccucucccgc cugcaaauga gaggccggcc uaacauuaca      300

caugcuguuc ccaaagccgc gauggugacc gcccugcgca agcuccacgc ugggaaagug      360

agagaggacg gacgggucga aaucccucau cuggauggcc acgccucucc cggggcugac      420

ggacaggagc gcgugagcga gauuaucucc uucgccgaaa cagauggccu ugcgucuagc      480

agaguucggc uguacuuuuu cauuuccaau gagggcaacc agaaucucuu ugugguccag      540

gccagccugu ggcuuuaucu gaagcuccug cccuacgugc uggaaaaagg gucucgcaga      600

aagguucggg ugaaggucua uuuccaagag cagggacaug gcgaccgcug gaacauggug      660

gagaaaagag uggaucucaa gcgguccggg uggcacaccu uuccucugac agaagcuauc      720

caggcccuuu ucgagagagg agaacgccgg cugaaucucg acguccagug ugauagcugc      780

caagagcugg cuguugugcc gguguuuguc gaccccggcg aagagucuca cagaccuuuc      840

gugguugugc aggcccgccu uggggauucc cggcauagaa uccgcaaacg gggacuggag      900

ugugacggca gaaccaaccu cugcugucgc cagcaguuuu ucauugacuu ucggcugauc      960

ggcuggaaug auuggauuau cgcccccacg ggguacuaug gaaacuacug cgaaggcagc     1020

uguccugcuu aucuggcggg gguccccgga ucugccucca gcuuccacac cgcugugguu     1080

aaucaauaca gaaugcgcgg ccucaacccg gggacaguca auuccugcug uauuccuacc     1140

aagcugucua caaugagcau gcuuuacuuc gacgaugagu auaacaucgu gaaacgggac     1200

gugcccaaua ugauugucga agagugcggc ugcgccugag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  1921
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt5)

<400>  1921
gggagaaagc uuaccauggc ccugagagug cuccugcuua ccgcucugac acucugccac       60

ggcuucaacc uggacacgga gaaugccaug accuuucagg aaaacgcgcg gggguucgga      120

caaagcgugg uucagcuuca gggcucccgc gugguggucg gggcucccca ggagaucgug      180

gccgccaauc aaagaggauc ucuguaccag ugugauuaua gcacaggcuc cugcgaaccu      240

auucggcucc agguuccggu ggaggcuguc aacaugucuc uggggcugag ccucgccgcu      300

accacauccc cuccucagcu gcuugccugu ggacccaccg ugcaucaaac augcucugaa      360

aauaccuacg uuaagggccu guguuuucuc uucggcagca accugcgcca gcagccucag      420

aaauuucccg aggcgcuuag agggugcccu caagaggacu ccgauaucgc cuuccugauu      480

gacggaagcg gcucuaucau uccgcacgau uuucggcgca ugaaggaguu cguguccacg      540

gucauggaac agcucaaaaa gagcaaaacc cuguuuucuc ugaugcagua uuccgaagag      600

uucagaaucc auuuuacauu caaggaguuu caaaauaacc ccaauccucg gagccucgug      660

aagcccauca cccagcugcu ugggcgcaca cacaccgcua cgggaauuag aaaagugguc      720

cgggaacugu ucaacaucac aaauggcgcc cgcaagaacg cuuucaaaau ucucguugug      780

aucaccgacg gggagaaguu uggagauccu cugggcuacg aagacgugau ucccgaggcc      840

gauagagaag gcgucauccg guaugugauu gggguuggag acgcguuccg cucugagaaa      900

uccagacagg agcuuaauac aaucgccagc aagccgccuc gggaucaugu guuucagguc      960

aacaauuucg aagcucugaa gaccauccaa aaccagcuca gagagaaaau uuuugccauc     1020

gaaggcaccc agacaggguc cucuagcucc uucgagcacg aaaugagcca ggagggauuu     1080

ucugcugcca uuacguccaa cggcccccug cugagcaccg uggggucuua cgacugggcc     1140

ggaggcguuu uccucuauac aagcaaggag aaauccaccu uuaucaauau gacacgcgug     1200

gauucugaca ugaacgacgc uuaccugggc uacgcggccg cuauuauccu ucggaauaga     1260

guccaaagcc uggugcucgg ggccccucgc uaucagcaca ucggacuggu cgccauguuc     1320

cggcagaaca ccggcaugug ggaauccaau gcuaacguga aggggacgca gauuggagcc     1380

uacuuuggcg cgagccuuug uucuguugau guggacucca augggagcac agaucugguc     1440

cucaucggcg cuccccauua uuacgagcaa accagaggag gccagguguc uguuugcccc     1500

cugccucgcg ggcgggccag auggcagugu gacgccgugc uguauggaga acagggccaa     1560

ccgugggggc gcuucggagc ugcccucacc guccugggcg augugaacgg ggacaaacuu     1620

acagaugugg cuauuggcgc ccccggagag gaagacaauc ggggcgcggu uuaccuguuu     1680

cacgggaccu ccggaagcgg caucuccccu ucucauagcc agagaauugc cggguccaag     1740

cucucucccc gccugcagua uuucggacaa agccuguccg gcgggcagga ucuuacaaug     1800

gacggccucg ucgaucugac ggugggagcu cagggccacg ugcugcuccu gcggagccag     1860

ccuguccuua gagugaaagc caucauggag uucaaccccc gggagguugc ucgcaaugug     1920

uuugaaugca acgaccaagu cgugaagggg aaggaggccg gagaaguuag agugugucug     1980

cacguccaga aaucuacccg ggacagacuc cgcgagggcc agauccaguc cgugguuaca     2040

uacgaucugg cgcuggacag cgggcggccg cauucuagag ccguguucaa ugagaccaag     2100

aacuccacac gcagacaaac ccagguccuu ggacucacgc agaccugcga aacacugaaa     2160

cugcagcucc cuaauugcau ugaggauccc gugagcccua ucgugcugcg gcuuaacuuu     2220

ucucuggucg gcacaccccu cagcgcuuuc gggaaccugc gcccuguucu ggccgaagac     2280

gcucaaagac uuuuuaccgc ccucuucccc uuugagaaga auuguggcaa cgauaauauu     2340

ugccaggacg aucuguccau caccuucagc uuuaugucuc uggacugucu cgugguggga     2400

ggcccgcggg aguucaacgu cacggugaca guucgcaaug auggggaaga cuccuacaga     2460

acccagguga cauuuuucuu uccucuggau cuuagcuauc ggaaagucuc cacccugcaa     2520

aaccagcgcu cucagagaag cuggcggcuc gccugcgagu ccgcuucuag caccgaagug     2580

uccggagcgc ugaagucuac aagcuguucc auuaaucacc ccaucuuccc cgagaacagc     2640

gaaguuacgu ucaauauuac cuuugacgug gauucuaagg ccucccuggg caacaaacuu     2700

cuccugaagg cuaaugucac aagcgagaac aauaugccuc gcaccaacaa aacagaguuc     2760

cagcuggaac ucccggugaa guacgccguu uauauggugg ucaccucuca uggggugucc     2820

acgaaauacc ugaauuuuac agccagcgag aacaccucua gagugaugca acaccaguau     2880

caggucucca accuuggaca gcggagccug cccaucuccc ucguuuuccu ggugccugug     2940

agacugaauc aaaccgucau cugggaccgc ccccagguga cauuuagcga aaaccuuucu     3000

agcacaugcc auaccaagga gcggcugccu ucccacucug acuuccucgc ugaacugaga     3060

aaggcccccg uugugaauug uagcauugcg gucugccagc gcauccagug ugauauuccc     3120

uuuuucggca uccaagagga auuuaacgcu acgcucaaag gcaaucuguc cuucgacugg     3180

uacauuaaga ccucucacaa ccaucuucug aucgugagca cagccgagau ccucuuuaau     3240

gauuccguuu ucacccugcu gcccgggcag ggagccuucg ugcggucuca gacagagacc     3300

aaagucgaac cguuugaggu gccuaacccc cuuccucuga uugucggcag cuccgucggg     3360

ggacuccugc uccuggcucu uaucacggcc gcgcuguaua agcucggcuu cuuuaaaaga     3420

caguacaagg acaugaugag cgaaggggga cccccgggcg cugagccuca augaggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  1922
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt5)

<400>  1922
gggagaaagc uuaccauguu cagccugaag acccuccccu uucugcuucu gcuccacgug       60

cagaucucca aagccuuccc ugucucuagc aaggagaaaa acacaaagac gguucaagac      120

uaccuggaaa aauuuuauca gcuuccgucc aaucaguacc agucuaccag aaagaacggc      180

acaaauguga uuguggagaa gcugaaagaa augcaacggu ucuuugggcu caacgucacc      240

ggaaagccca augaggaaac acuggauaug augaaaaagc cucgcugcgg cgugcccgac      300

agcgggggau ucaugcugac cccuggcaac cccaaauggg agagaacaaa ucucaccuau      360

cggauccgca acuacacgcc ucagcugucc gaggcugaag uugagagagc cauuaaggau      420

gcguuugaac uuuggucugu ggcuagcccg cugaucuuca cccggauuuc ccagggggag      480

gccgacauca auaucgccuu uuaucagcgc gaucauggag acaacagccc cuucgauggc      540

ccuaauggca uucucgcuca cgccuuucaa cccgggcagg gaaucggcgg ggacgcucau      600

uucgaugccg aggaaacaug gaccaacaca ucugcgaauu acaaccuguu ucuugucgcc      660

gcucacgagu ucggacauuc ccugggccuc gcccacagcu cugacccugg ggcucugaug      720

uaucccaauu acgccuucag agaaaccucc aacuacagcc ugccgcagga ugacauugau      780

ggaauccagg cgauuuaugg ccucucuucc aacccuaucc aacccacggg cccuagcaca      840

cccaagcccu gugacccuuc ccugaccuuu gacgccauua caacccuucg gggagagauc      900

cuguucuuua aagaucgcua cuucuggaga cggcacccgc agcuccagcg cguggaaaug      960

aauuuuaucu cucuguucug gcccagccuu ccuaccggga uucaagcugc cuaugaggac     1020

uuugauagag accugaucuu ccucuuuaag ggcaaccagu acugggcucu guccggguau     1080

gauauucugc agggauaccc caaagacauc agcaauuaug gcuucccuuc uuccguucag     1140

gccauugaug ccgcuguguu uuaccggagc aagacauacu ucuuugucaa cgaccaauuc     1200

uggcgcuaug auaaucagag acaguucaug gagcccgggu acccgaaauc uaucagcgga     1260

gcguuuccug gcaucgaauc caagguggac gccguguucc agcaagagca cuuuuuccau     1320

gucuuuucug gcccccggua uuacgcuuuc gaucucauug cccagagagu uacgcgcgug     1380

gcccggggga acaaauggcu gaauugcaga uauggaugag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  1923
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt5)

<400>  1923
gggagaaagc uuaccaugag ccuguggcag ccccucgugc ugguccuucu gguucucggc       60

ugcuguuucg ccgcuccuag acaacggcag uccacccugg ugcuuuuucc gggggaccug      120

cgcacaaacc ucacggauag acagcuggcc gaggaauacc uguaucggua cggauauacc      180

cgcguggcgg agaugagagg cgaaucuaaa agccucgggc ccgcucugcu ucugcuccag      240

aaacaacugu cccuuccuga gacaggagaa cuggacucug ccacccucaa ggccaugcgg      300

acaccccgcu gcggcguccc ugaucugggg agauuccaga ccuuugaggg agaccugaaa      360

uggcaccauc acaauaucac auacuggauu cagaacuaua gcgaggaucu cccccgggcu      420

gugaucgacg augccuucgc ucgcgccuuu gcgcuguggu ccgccguuac cccucuuacg      480

uucaccagag uguacucucg ggacgcugau auugucaucc aguuuggcgu ggccgaacau      540

ggcgacgggu auccguucga uggaaaggac ggccugcucg cucacgccuu ucccccuggg      600

cccgggauuc aaggcgaugc gcauuucgac gacgaugagc uguggagccu ugggaaagga      660

guuguggucc cuacacgcuu uggcaaugcc gacggcgcug ccugucacuu ccccuuuauc      720

uucgaaggga gauccuacag cgcuugcacc acagauggac ggucugacgg ccugccgugg      780

uguuccacca cggccaacua cgauacagac gaucgcuucg gguuuugccc uagcgagaga      840

cucuauaccc aggacggaaa ugccgauggc aagcccuguc aguucccuuu uaucuuccag      900

gggcaaucuu acuccgcuug cacaaccgac ggacggagcg auggcuauag auggugugcg      960

accacagcca acuacgaccg cgacaagcug uuuggcuucu gccccacgcg ggcugauucu     1020

accgugaugg gaggaaauuc cgccggcgag cugugugugu uucccuucac auuucucggg     1080

aaagaauaua gcacaugcac cuccgaggga agaggcgacg ggcgccugug gugcgccacc     1140

acgucuaacu ucgauagcga caagaaaugg ggcuuuuguc cugaucaggg auacucccuu     1200

uuccuggucg cugcccacga auuuggccau gcgcucgggc uggaccacag cucuguuccg     1260

gaggcucuua uguaucccau guaccgguuc acagaaggac cuccccugca uaaggaugac     1320

gugaauggca uuagacaccu cuacgggccu cgccccgagc cggagccucg gcccccuacc     1380

accacaacac cccagccuac cgcgcccccg acggugugcc cuaccggacc ucccacaguc     1440

caccccuccg aaagaccgac cgccggcccc acagggccuc ccagcgcugg cccuaccgga     1500

cccccuacgg ccggccccuc uaccgcuaca accgugccgc ugagcccugu ugaugacgcc     1560

uguaacguga auaucuucga ugcgauugcc gagaucggga accaacugua ucucuuuaaa     1620

gacggaaagu acuggcgcuu cuccgaaggc cgggggucua gaccccaggg accuuuucug     1680

auugcugaua aguggcccgc ccuuccgcgc aaacuggaca gcgucuucga ggaacggcuc     1740

uccaagaaac uguuuuucuu uagcggcaga cagguguggg uuuauacagg ggcuucugug     1800

cugggcccuc ggcgccuuga caagcucgga cugggcgccg augucgccca ggugaccggg     1860

gcccugagau ccggacgggg caaaaugcuc cuguucagcg ggagacgccu uuggcgguuu     1920

gacgucaagg cucaaauggu ggaucccaga ucugccuccg agguugaccg cauguucccu     1980

ggagugcccc uggauacgca ugacgucuuu caguacagag agaaggcuua uuucugccag     2040

gaucgguuuu acuggcgcgu gagcuccaga ucugaacuca aucagguuga ccaagugggc     2100

uaugucacau acgauauccu gcaguguccc gaggacugag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  1924
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt5)

<400>  1924
gggagaaagc uuaccaugca ccccggcgug cuggccgcuu uccucuuucu gagcuggacc       60

cauugcagag cccuuccucu gccguccggg ggagacgagg augaccucuc ugaagaggau      120

cugcaguucg cggaacggua ccuucgcagc uauuaccacc ccacaaaccu ggcuggcauc      180

cucaaggaga augccgccuc cucuaugacg gaaagacugc gggagaugca gagcuuuuuc      240

gggcuggagg ucaccggaaa acucgacgau aacacacugg acguuaugaa gaaaccucgc      300

uguggcgugc ccgauguggg ggaauauaau gucuuuccua gaacccuuaa gugguccaaa      360

augaaccuga cauaccggau ugugaauuau acccccgaca ugacacauuc ugagguugaa      420

aaggcuuuca agaaagccuu uaaggugugg agcgauguca ccccucucaa cuucacgcgc      480

cugcacgacg gaaucgcuga uauuaugauc uccuuuggca uuaaagagca uggcgacuuc      540

uacccguuug augggcccag cggacuucug gcccacgcgu ucccucccgg cccuaauuau      600

gggggagacg cccacuuuga cgaugacgag accuggacau cuuccagcaa gggcuacaac      660

cucuuccugg uggcugccca ugaguucggg cacucucugg gacucgauca uuccaaagac      720

cccggcgcuc ugauguuucc gaucuacacc uauacaggca agagccacuu caugcuuccu      780

gaugacgaug uucaagggau ccagucucug uacggacccg gcgacgagga uccuaauccc      840

aagcacccca aaaccccuga caagugcgau ccgucccuca gccuggacgc cauuacgucc      900

cuuagagggg aaacaaugau cuuuaaagac cgguucuuuu ggcgccugca uccccagcaa      960

guggaugcgg aacucuuccu gaccaagucu uuuuggccug aacugcccaa cagaauugac     1020

gccgcuuaug agcacccuag ccaugaucuc aucuucauuu uucggggacg caaauucugg     1080

gcccugaaug gcuacgacau ccuugagggg uaucccaaga aaauuuccga acugggacuc     1140

ccgaaggagg ucaagaaaau cagcgcugcc gugcacuuug aagauacagg caagacccug     1200

cuuuucucug gcaaccaggu guggagauac gacgauacca aucauaucau ggacaaagau     1260

uauccucggc ugauugagga agacuuuccc gggaucggag auaaggucga cgccguuuac     1320

gagaaaaacg gcuacauuua uuucuucaau gggccuaucc aguuugagua cuccauuugg     1380

agcaaccgca ucgugagagu gaugcccgcu aacucuaucc ucugguguug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  1925
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt5)

<400>  1925
gggagaaagc uuaccaugga gacccccaac acaacggaag acuacgauac cacaaccgag       60

uucgacuaug gcgaugccac accuugccag aaggugaaug aaagagcuuu uggggcccaa      120

cugcucccgc cccuguacag ccuugucuuc guuaucggac uggugggcaa cauucucgug      180

guccuggugc uuguucagua uaaacggcug aagaauauga ccuccaucua ccuccugaac      240

cuggcgauuu cugaccuccu guuucuuuuc acacugccuu uuuggaucga uuauaaacuc      300

aaggacgauu ggguguucgg ggacgcuaug uguaaaauuc ugagcggauu uuacuauacc      360

ggccuuuacu ccgagaucuu cuuuaucauu cugcucacga ucgaucgcua ccuggccauu      420

guccacgccg uguucgcucu gagagcccgg accguuacau uuggggugau caccucuauu      480

aucauuuggg cucucgccau ccuggcgagc augcccggac uuuauuucuc caagacacag      540

ugggaauuua cccaucacac gugcucucug cauuucccuc acgagagccu ccgcgagugg      600

aagcuguucc aggcccuuaa acugaaucuc uuuggccugg uccugccccu ccuggugaug      660

aucauuuguu acacaggcau cauuaagauc cuucugagac ggccuaacga gaaaaagucc      720

aaagcugugc gccucauuuu cgucaucaug aucaucuuuu uccuguuuug gaccccguau      780

aaucuuacaa uucugauuag cguuuuccaa gacuuucucu ucacccauga augcgaacag      840

ucuagacacc uggaucuggc cguccaggug accgagguga ucgcuuacac acacuguugc      900

gugaaccccg uuauuuaugc cuuugugggg gagcgguucc gcaaguaccu cagacagcug      960

uuucaucggc gcgucgcggu gcaccuuguu aaguggcugc cuuuccucuc cguggacaga     1020

cuggaacggg ucagcucuac gucccccagc accggagagc augaacuguc ugccggcuuu     1080

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  1926
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt5)

<400>  1926
gggagaaagc uuaccaugag aacccuggcc ugccuccugc uucugggcug uggguaccuc       60

gcucacgugc uggccgagga agcggagauc ccccgggaag ucauugagcg ccuugcuaga      120

agccagaucc auuccauucg ggaccugcaa cgccuccugg aaaucgauuc uguuggaagc      180

gaggacuccc uggauacauc ucucagagcc cacggcgugc augccacgaa gcacgugccu      240

gagaaacggc cgcugcccau ucgcagaaag cggagcaucg aagaggcugu cccugccgug      300

ugcaaaaccc gcacaguuau cuaugaaauu cccagauccc agguggaccc uaccucugcu      360

aacuuccuua ucuggccccc uugugucgag gugaagcggu gcacagggug uugcaauacc      420

agcuccguua aaugucagcc gagccgcgug caucacagau cugucaaggu ggccaaggug      480

gaguacgucc ggaaaaagcc caaacugaag gaaguucagg ugcgccucga ggaacaccug      540

gagugcgcgu gugccacaac cucccuuaac ccugauuaua gagaagagga cacgggacgg      600

cccagagaga gcggcaaaaa gcgcaagcgg aaaagacuga agccuaccug aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  1927
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt5)

<400>  1927
gggagaaagc uuaccaugaa cagaugcugg gcccuguucc ucagccugug uugcuaccuu       60

cggcuggugu ccgcugaggg cgaccccauc ccugaggaac ucuaugaaau gcugucugau      120

cacagcauuc gcuccuuuga cgaucuucag agacugcucc auggggaccc gggagaggaa      180

gauggcgccg agcuggaccu gaauaugacc cggucucaca gcgggggaga gcucgaaucc      240

cuggcgcgcg gcagacgguc ucuugggagc cugacaaucg cugagcccgc caugauugcc      300

gaauguaaga cgcgcaccga ggucuucgag aucuccagac ggcucauuga ucgcacaaac      360

gcuaauuuuc ugguuuggcc ucccugcgug gaagugcaaa gauguagcgg augcuguaac      420

aaucggaacg uccagugccg cccuacccag gugcagcuua gacccguuca agugcggaaa      480

aucgagaucg uccgcaagaa accuauuuuc aagaaagcca cagugacccu ggaagaccau      540

cucgcuugua agugcgagac aguugccgcg gccagaccgg ugacccgguc ucccggcggc      600

ucccaggaac agagagcuaa gacgccucag acccgcguca caauccggac cgugagagug      660

cgccggcccc cuaaagggaa gcacagaaaa uuuaagcaua cacacgauaa aaccgcccug      720

aaggagacgc ugggagcuug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  1928
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt5)

<400>  1928
gggagaaagc uuaccaugag ccuguucggc cuccugcuuc ugaccuccgc ccucgcuggg       60

cagagacaag gaacacaggc cgagucuaac cugagcucca aguuucaguu cucuagcaau      120

aaagaacaga acggcgugca agacccccag cacgagcgga ucauuacggu cuccaccaau      180

gggucuaucc auagcccucg cuuuccgcac acauacccca gaaacaccgu ucuugugugg      240

cggcuggugg cggucgaaga gaaugugugg auucagcuca cauucgauga acgcuuugga      300

cuggaggacc cugaggauga caucugcaag uaugauuucg uugaagugga ggaacccucc      360

gacggcacca uucuggggag auggugugga agcggcacag ucccuggcaa acagaucucu      420

aaggggaacc aaauccggau ucgcuuugug uccgaugagu acuuccccag cgagccugga      480

uuuugcaucc auuauaauau uguuaugccg caguucaccg aagcuguguc ucccuccguc      540

cucccuccca gcgcccugcc ucuugaccug cucaacaaug ccaucacggc uuuuucuacc      600

cuggaggauc uuauuagaua ccuggaaccc gagcgguggc agcucgaccu ggaagaucug      660

uaucgcccga cauggcagcu ccugggcaaa gccuucgugu uugggagaaa gucccgggug      720

gucgaccuua accugcucac cgaggagguu cgccuguaca gcuguacacc uagaaauuuc      780

uccgugucua uccgggagga acuuaagcgc accgauacga uuuucuggcc cggaugccug      840

cucgugaaaa gauguggcgg gaacugcgcu uguugccugc acaauuguaa cgaaugccaa      900

ugugucccua gcaaggugac caaaaaguau caugagguuc ugcagcuccg gcccaaaaca      960

ggagugagag gccugcacaa gucccuuaca gacgucgccc uggaacacca ugaggagugc     1020

gacugcgugu gucgcggcag caccggggga ugaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  1929
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt5)

<400>  1929
gggagaaagc uuaccaugca cagacugauc uucguguaca cccucauuug cgccaacuuu       60

uguagcugcc gggacacauc cgcuacgccc cagucugcca gcaucaaggc gcugcgcaau      120

gcuaaccuua gacgggauga ccuguaucgc agagaugaga ccauucaagu caaaggcaau      180

ggguacguuc aguccccucg guucccgaac ucuuaucccc gcaaucuccu gcuuacaugg      240

agacugcaua gccaggaaaa cacccggauc cagcucgugu uugacaauca auucggacug      300

gaggaagccg agaacgauau uugucgcuac gacuuugugg aagucgagga uaucuccgag      360

acaucuacca ucauuagagg ccgguggugc gggcacaagg aagugccucc ccgcaucaaa      420

agcagaacaa aucagauuaa gaucaccuuc aaauccgacg auuauuuugu ugccaagccu      480

ggauucaaga uuuacuauag ccugcucgag gacuuucagc ccgcugccgc uucugaaacg      540

aacugggagu ccgugaccag cucuaucucc ggcgucagcu acaauucucc uuccgugaca      600

gauccgaccc ugauugccga cgcgcuugau aaaaagaucg ccgaguucga cacaguugaa      660

gaccugcuca aauacuuuaa ccccgagagc uggcaggaag aucuggagaa uauguaucuu      720

gacaccccuc gguaccgcgg gagauccuau caugaucgga agucuaaagu ggaccuggau      780

agacucaacg acgaugcuaa gcgcuacagc uguacgcccc ggaauuauuc cgucaacauc      840

agagaggaac ugaagcuggc caacguggug uucuuuccuc gcugccuccu gguccaacgg      900

uguggaggca auugcggcug ugggacaguu aacuggagaa gcugcaccug uaauucugga      960

aaaacaguga agaaauacca cgaggugcuu caguucgaac ccggccauau uaagcgccgg     1020

gggagagcua aaaccauggc ccuggucgac auccagcucg aucaccacga gcgcugcgac     1080

ugcauuuguu ccagccggcc gccuagauga ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  1930
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt5)

<400>  1930
gggagaaagc uuaccauggu gacccacagc aaguuccccg ccgcuggcau guccagaccu       60

cuggacacau cucuccggcu gaaaacguuu agcuccaagu cugaguacca gcuugucguu      120

aacgccgugc gcaaacugca agaaagcggg uucuauuggu ccgcggugac cggaggcgag      180

gcuaaucucc ugcuuucugc cgaaccggcc gggacauuuc ugaucagaga uagcuccgac      240

cagcggcauu ucuuuacccu cagcgucaag acacagucug gaaccaaaaa ccugcgcauu      300

cagugcgagg gcggguccuu cagccugcaa ucugauccca gauccacaca gccugugccc      360

cgguuugacu guguucucaa gcuggugcac cauuacaugc cucccccugg agcuccgagc      420

uuccccucuc cucccaccga accuuccagc gagguccccg agcagccguc cgcccagccu      480

cuucccggcu cuccuccccg cagagcuuau uacaucuaua gcggcgggga aaagauuccc      540

cuggugcucu cccggccucu gagcucuaau guugccacgc uucaacaccu gugccgcaaa      600

accgugaacg gacaucucga uuccuacgag aaggucacac agcugccggg ccccaucaga      660

gaauuucugg accaguauga ugcgccucuc ugaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  1931
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt5)

<400>  1931
gggagaaagc uuaccauggu gcccagcgcc ggccagcugg cucucuucgc ccuggggauc       60

guccuugcgg cuugccaagc ccuggagaac uccaccucuc cucucagcgc cgacccgccc      120

guugcugccg cugugguguc ccacuuuaau gauuguccug acucucauac acaguucugc      180

uuucacggaa cguguagauu ccugguccag gaagauaagc ccgccugcgu gugucauagc      240

ggcuacguug gggcgcggug cgagcacgcc gaccuucugg cuguggucgc cgcuucccag      300

aaaaagcaag ccauuaccgc gcucgugguu gugucuaucg ucgcccuggc ugugcugauu      360

aucacaugug ugcucauuca uugcugucag guccgcaaac acugcgaaug guguagagcc      420

cugaucugcc ggcacgagaa gccuagcgcc cuucugaaag gacgcaccgc uugcugucau      480

uccgaaacag uugugugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  1932
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt5)

<400>  1932
gggagaaagc uuaccaugcc cccuagcggc cugagacucc ugccgcuucu gcucccccug       60

cuuuggcugc ucgugcugac cccugggcgg cccgccgcug gacuguccac augcaagacg      120

aucgacaugg agcucgucaa acgcaagaga auugaagcca uccggggcca gauucugucu      180

aaacuucgcc uggcgagccc ucccucccaa ggggagguuc cuccgggacc ccucccugaa      240

gcugugcugg cccuuuacaa cucuaccaga gaucgggugg ccggcgagag cgcugaaccc      300

gagccugagc ccgaagccga cuauuacgcu aaggagguca cacgcgugcu gaugguugaa      360

acccacaaug agaucuauga uaaauucaag caguccacac auucuauuua cauguuuuuc      420

aacaccagcg agcucagaga agccgugccg gagccugucc ugcugucccg ggcggaacuc      480

cgccugcuua gacugaagcu caaaguggag cagcacguug aacuguauca gaaguacagc      540

aauaacucuu ggcgguaucu uuccaaucgc cugcucgccc ccagcgacuc uccugagugg      600

cuguccuuug augugacagg ggucgugaga caauggcuga gccggggagg cgagaucgaa      660

ggcuuccgcc ucucugcuca uuguuccugc gacagcagag auaacacccu ucagguggac      720

aucaaugggu uuacgaccgg acggagaggc gaucuggcca caauucacgg gaugaaccgc      780

cccuuccugc uccugauggc uacaccccuu gagcgggccc agcaucugca guccucuaga      840

caccgccggg cgcucgacac caauuacugu uuuagcucca ccgagaaaaa cugcuguguc      900

agacaacugu acaucgauuu ccgcaaggac cugggaugga aauggauuca cgaaccuaag      960

ggcuaucaug ccaauuuuug ccucgggccg ugucccuaca ucuggagccu ggauacgcag     1020

uauucuaagg uucuugcucu guacaaccag cacaauccug gagccuccgc ugcccccugc     1080

ugugugccuc aggcccucga accccugccg auuguguauu acgucggccg gaaaccuaag     1140

guggagcaac ugagcaacau gaucguuaga ucuugcaaau guagcugagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  1933
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt5)

<400>  1933
gggagaaagc uuaccaugca cuacugcgug cugagcgccu uccucauccu gcaucuuguc       60

accguugcuc ugucccucuc uacauguagc acgcuggaca uggaucaguu uaugagaaag      120

cggauugagg ccauccgcgg ccaaauucuu uccaaacuga agcucaccuc ucccccugaa      180

gacuauccgg agcccgaaga ggugccuccc gaagugauca gcauuuacaa cuccacaaga      240

gaucugcugc aggagaaagc gucucggcgc gcugccgccu gcgagagaga acggagcgac      300

gaggaauauu acgcuaagga ggucuauaaa aucgauaugc cucccuucuu uccuuccgag      360

aaugccaucc cgcccaccuu cuaccgcccu uauuuuagaa uugugcgguu cgacguuagc      420

gcuauggaaa agaacgccuc uaaucucgug aaggcggagu uucgcgucuu cagacugcag      480

aaccccaaag cccgggugcc ugaacagcgc aucgagcuuu accaaauucu gaaguccaaa      540

gaucucacaa gccccaccca gagauacauc gacucuaagg uugugaaaac acgggcugaa      600

ggggaguggc uguccuuuga ugucaccgac gccgugcacg aguggcuuca ucacaaggau      660

cgcaaucugg gauucaagau uagccuccau uguccgugcu guacguuugu gccuucuaac      720

aauuauauca uucccaacaa auccgaggaa cuggaagcua gauucgccgg caucgacggg      780

accagcacau acaccuccgg agaucagaag acaaucaaau cuacccggaa gaaaaauagc      840

ggcaagacgc cucaucugcu ccugaugcuu cugcccuccu auagacucga gagccagcaa      900

acaaaccgcc ggaaaaagag agcgcuggac gccgcuuacu gcuuucgcaa uguccaggac      960

aacuguugcc uucggccccu guauauugau uucaagagag accucgggug gaaauggauc     1020

cacgaaccua agggauacaa ugccaacuuc ugugcuggcg ccugcccgua ucuguggucu     1080

uccgauaccc agcacagccg cguucugucu cucuacaaua caauuaaccc cgaggccagc     1140

gcuuccccuu guugcguguc ucaggaccug gagccccuua ccauccugua cuauauuggc     1200

aaaaccccua agaucgaaca acucagcaac augaucguga aauccugcaa guguagcuga     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  1934
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt5)

<400>  1934
gggagaaagc uuaccaugaa gaugcaccuu cagagagccc ucgugguccu ggcucugcug       60

aacuucgcca ccguuagccu cucccugucu acaugcacga cccuugacuu uggccauauc      120

aaaaagaaac ggguggaggc gauucgcggg caaauccuga gcaagcucag acugacaucu      180

cccccugaac cgaccgugau gacacacguc cccuaccagg ugcuggcucu cuauaauucc      240

acccgggagc ugcuugaaga gaugcaugga gaacgcgagg agggcuguac acaggaaaac      300

accgagagcg aauacuaugc caaagagauu cacaaguucg auaugaucca ggggcuggcc      360

gagcauaaug aacucgcugu uugcccuaag ggaauuacgu ccaaaguguu uagauucaac      420

gucucuagcg uggagaagaa ucggaccaac cuguuucgcg ccgaguucag aguucuucgg      480

gugcccaauc cuuccagcaa acgcaacgaa caaagaaucg aacuguuuca gauccuccgg      540

cccgacgagc acauugcuaa gcagcgcuac aucggcggga aaaaucugcc uacaagagga      600

accgccgagu ggcugucuuu cgaugucaca gacaccgugc gggaauggcu ccugcgcaga      660

gaguccaacc uuggccugga aauuagcauc cacuguccgu gccauacguu ucagcccaau      720

ggcgauauuc ucgagaacau ccacgaagug auggagauua aguucaaggg ggucgacaau      780

gaggaugacc auggacgggg cgaucugggg agacuuaaaa agcaaaaaga ccaccacaac      840

ccucaucuga uccucaugau gauucccccu caccgccugg auaaucccgg acagggcggg      900

cagcggaaga aaagagcgcu ggacacaaac uauuguuuuc gcaaccucga agagaauugc      960

uguguucggc cgcuguacau cgauuucaga caggaccuug gauggaagug ggugcaugaa     1020

ccuaaaggcu auuacgccaa cuuuugcucu ggccccuguc cuuaccugcg cuccgcugac     1080

accacacaca gcaccgugcu cgggcuguau aauacccuua accccgaggc cucugcuucc     1140

cccugcugug ucccucaaga ucuggaaccg cucacaaucc uguacuaugu gggacggacg     1200

cccaagguug agcagcugag caauauggug gucaaguccu gcaaaugcuc uugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  1935
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt5)

<400>  1935
gggagaaagc uuaccauggc ccccguggcu gucugggccg cgcuggcugu uggccucgag       60

cugugggccg ccgcucacgc ccuuccugcu cagguggccu ucaccccgua cgcgcccgaa      120

ccugggagca caugcagacu gcgggaguau uacgaccaaa cggcccagau guguugcucc      180

aaguguucuc ccggacagca ugcuaaagug uuuugcacca agacaagcga uaccgucugu      240

gacuccugcg aagauucuac auauacccag cucuggaacu gggugccuga gugucugagc      300

ugcggcuccc gcuguucuag cgaccaaguu gaaacacagg ccugcaccag agagcagaau      360

cggaucugua cgugccgccc cgggugguac ugcgcucuuu ccaaacagga gggauguaga      420

cugugcgccc cucuccggaa gugucgcccg ggcuucgggg uggcgagacc cggaaccgaa      480

acaagcgaug ucgugugcaa accuugugcc cccggcaccu uuucuaacac aaccuccagc      540

acggacauuu gccggccuca ccaaaucugu aauguugugg cuauucccgg caacgccucu      600

auggaugcug ucugcacauc caccagcccg acacgcucua uggccccugg ggccgugcau      660

cugccccagc cuguguccac cagaagccag cacacccagc ccacacccga gccuuccacg      720

gcuccgucua ccagcuuccu gcuccccaug ggaccuuccc cucccgcgga aggcagcaca      780

ggggacuuug cccugcccgu cggacuuauc guuggcguga ccgcucuggg gcuccugauu      840

aucggagugg ucaauugugu gaucaugaca caaguuaaga agaaaccgcu uugccugcag      900

cgggaggcca aggugccuca ucuccccgcc gauaaagcuc gcggcaccca gggcccugag      960

caacagcauc ugcugauuac ggcccccucu uccagcucua gcucccucga aucuagcgcg     1020

uccgcucugg acagacgggc cccuacacgc aaccagcccc aggccccggg ggucgaggcu     1080

agcggagccg gcgaagcuag agccucuacc ggguccagcg auucuucccc uggaggccac     1140

gggacccaag ugaauguuac auguaucgug aacgucugca gcuccucuga ccacagcucc     1200

cagugcucua gccaggcguc cagcaccaug ggagauacag acucuucccc cagcgagucu     1260

cccaaggacg aacaggugcc uuucuccaaa gaggagugug ccuuucggag ccaacuugaa     1320

acgccggaga cccugcucgg cucuacagaa gagaagcccc ugccucuugg cguccccgau     1380

gcugggauga agccuagcug aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  1936
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt5)

<400>  1936
gggagaaagc uuaccaugcc cgugaugaga cuguucccuu gcuuucucca gcugcuugcc       60

ggccuggcuc ucccggccgu ucccccucaa cagugggcgc ugagcgcugg gaacggaucc      120

ucugaggucg aaguggugcc cuuccaggag gucuggggcc ggagcuacug ucgcgcccuu      180

gaaagacugg uggacguugu guccgaguau ccuucugaag ucgagcacau guuuagcccc      240

uccugcgugu cucuccugcg guguaccggg ugcuguggag augagaaucu gcauugcguu      300

ccuguggaaa cagccaacgu cacgaugcag cuccugaaga uccgcagcgg cgacagaccg      360

uccuacgugg agcuuaccuu cagccaacac gugcggugug aaugccgccc ccugagagag      420

aaaaugaagc cugagcggcg cagacccaaa gggcggggaa agcgcagacg ggaaaaacag      480

cgcccuacag auugucaucu cugcggcgac gcugucccca gacggugagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  1937
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt5)

<400>  1937
gggagaaagc uuaccaugac cgacagacag acagauacgg cccccagccc uuccuaccac       60

cuucucccgg gccggcgcag aaccguggac gcugccgcgu cucgggggca aggacccgag      120

ccugcucccg gcgggggagu cgaaggcguu ggggcccgcg gaguggcccu gaagcuguuc      180

gugcagcugc ucggcugcag cagauuuggc ggggcugucg ugcgggccgg agaggcugaa      240

ccuuccggcg ccgcgcgcuc ugccagcucc gggagagagg aaccccagcc ugaggaggga      300

gaagaggaag aggagaaaga agaggaacgg ggcccgcagu ggcgccuggg ggcuagaaag      360

cccggaucuu ggacaggcga ggccgcuguu ugugccgaua gcgcgccugc cgcucgggcu      420

ccccaagccc uugcccgcgc cuccggcaga gggggacggg uggcucgcag aggcgcggaa      480

gagagcgggc cuccccauuc uccgucccgg agaggaagcg ccucucgcgc uggcccuggg      540

cgggccuccg agaccaugaa cuuccugcuc agcugggucc acuggucucu ggcccugcuc      600

cuguaucuuc aucacgcuaa auggucccag gccgcgccca uggcugaagg aggcggccag      660

aaucaucacg aggugguuaa guuuauggac guguaccaga gaagcuauug ccacccuauc      720

gaaacacugg ucgauauuuu ccaagaguac cccgacgaaa ucgaguauau uuuuaaaccc      780

uccugugugc cucucaugcg cugcggggga uguugcaacg augagggccu ggaaugugug      840

ccgaccgagg aaucuaauau cacaaugcag auuaugcgga ucaagcccca ucaggggcag      900

cacaucggag agaugagcuu ccuucaacau aacaagugcg aauguagacc uaaaaaggac      960

cgcgcccggc aggagaaaaa guccgucaga ggcaaaggga agggccagaa gcgcaaacgg     1020

aagaaaagca gauacaaguc uugguccguu uaugugggag cccgcugcug ucugaugccc     1080

uggagccucc cuggccccca cccgugcggg ccuugcucug agcggagaaa acaccuguuu     1140

gugcaagauc cccagaccug uaagugcagc uguaaaaaua cggacucccg gugcaaggcu     1200

cgccagcugg aacucaacga gagaaccugu cggugcgaua agccuagacg cugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  1938
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt5)

<400>  1938
gggagaaagc uuaccaugaa cuuccugcuc agcugggugc acuggucccu ggcccuucug       60

cucuaccugc aucacgcuaa guggucucag gccgcgccca uggcugaggg cgggggacaa      120

aaucaucacg aagucguuaa auuuauggac guguaucaga gaagcuacug ccauccuauc      180

gagacccuug uggauauuuu ccaggaauau ccggacgaga ucgaauacau uuuuaagccc      240

uccugugucc cucugaugcg gugcggcggg uguugcaacg augagggacu cgagugugug      300

cccacagaag agucuaauau cacgaugcag auuaugcgca ucaaaccuca ccaaggccag      360

cacaucgggg aaaugagcuu ccugcagcau aacaagugcg aguguagacc caaaaaggac      420

cgggcccgcc aggagaagaa auccguuaga ggaaagggca aaggccaaaa gcggaaacgc      480

aagaagucua gauauaaaag cugguccgug uacgucgggg cccggugcug ucugaugccu      540

uggagccucc cgggacccca cccuugcggc cccuguucug aacgcagaaa gcaucuguuu      600

gugcaggauc cucagaccug caaaugcucc uguaagaaua cagacagccg gugcaaagcu      660

cgccagcuug agcugaacga aagaaccugu cggugcgaua agccccgcag augaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  1939
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt5)

<400>  1939
gggagaaagc uuaccaugag cccccugcuc agacggcugc uucuggccgc ucuccugcag       60

cuugccccug cgcaagcucc ggugucccag cccgacgccc cuggccacca gcgcaagguc      120

guuucuugga ucgaugugua caccagagcc acaugccagc cccgggaggu ggucgugccu      180

cugacgguug aacucauggg gaccguggcu aagcaacugg uccccagcug ugugacaguu      240

cagcgcugcg gaggcuguug cccugacgau gggcuggagu gugugccgac cggacagcau      300

caggucagaa ugcaaauucu caugauccgg uaucccuccu cucagcuggg cgaaaugagc      360

cuugaggaac acucccagug cgagugucgc ccuaagaaaa aggacucugc cgugaaaccc      420

gauagagcug ccacaccuca ucaccggccc cagccgcgca gcgugccugg gugggacucc      480

gcgcccggag ccccuagccc cgcugauauu acccauccca ccccugcccc gggccccucu      540

gcucacgccg cgccuuccac aacgagcgcc cugacccccg gcccugcugc cgcugccgcc      600

gacgcugcgg ccucuuccgu cgcuaaaggg ggagccugag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  1940
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt5)

<400>  1940
gggagaaagc uuaccaugca ucugcucggc uucuuuagcg uggccugcuc ccugcuugcu       60

gccgcgcugc uccccgggcc uagagaggcu ccggccgccg cugccgcuuu cgaaucugga      120

cuggaccuua gcgaugccga gcccgacgcg ggcgaagcca ccgcuuacgc cuccaaggau      180

cuggaggaac agcuccgguc ugucagcucc guugacgagc ugaugacagu gcuguauccu      240

gaguacugga aaauguauaa gugucaacuc cgcaaagggg gauggcagca caacagagaa      300

caggcuaauc ugaacucucg gacggaggaa accaucaagu uugccgcggc ccacuacaau      360

acagagauuc uuaaaagcau cgauaacgag uggcgcaaga cccagugcau gcccagagaa      420

guguguauug acgucggcaa ggaguucggg guggcuacaa auaccuuuuu caaaccuccc      480

ugcguuuccg uguaucggug uggaggcugc uguaacagcg aaggccugca augcaugaau      540

acaucuaccu ccuaccucag caagacgcug uuugagauca ccgucccucu uucucagggg      600

ccgaaacccg ugacaauuuc cuucgccaac cauaccagcu gucgcugcau gucuaagcug      660

gauguuuaua gacaggugca cuccaucauc cggcgcagcc ucccugcuac acugccccag      720

ugucaagccg ccaauaaaac cugcccuacg aacuacaugu ggaauaacca uauuugcaga      780

ugucuggcuc aggaagacuu uauguucucc ucugaugcgg gagacgauag cacagacggc      840

uuucacgaua ucugcgggcc caauaaggag cucgacgagg aaaccuguca gugcgucugu      900

cgggccggac ugcgcccggc uuccugcggc ccucacaagg agcuugacag aaacagcugu      960

cagugcgugu guaaaaauaa gcuguucccc ucucaaugcg gggccaaccg ggaauuugau     1020

gagaacacau gucagugcgu gugcaaacgc accuguccua gaaaucagcc ccucaacccc     1080

ggaaagugcg ccugugaaug caccgagucc ccucaaaaau gucugcuuaa gggcaaaaag     1140

uuccaucacc agacaugcag cuguuaccgg agaccgugca cgaaucgcca gaaggcuugu     1200

gagcccggcu ucucuuauag cgaagagguc ugccggugug uuccuuccua cuggaaaaga     1260

ccccagaugu cuugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  1941
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt5)

<400>  1941
gggagaaagc uuaccaugua cagagagugg guggucguua acguguucau gaugcuguau       60

gugcagcucg uccaaggcag cuccaaugaa cacgggcccg ugaagcgguc uagccagucc      120

acccuggagc gcucugaaca gcagaucaga gccgcuagcu cccuugagga acugcuccgg      180

auuacacauu cugaggacug gaaacugugg cgcugcagac uucggcucaa gagcuuuacg      240

uccauggaua gccgcucugc cucccacaga agcacccggu ucgcggcuac auuuuacgac      300

aucgagaccc ugaaaguuau ugaugaagag uggcaacgca cacaguguuc uccuagagaa      360

accugcgugg aggucgccuc cgagcuggga aagagcacaa acaccuucuu uaaaccgccc      420

ugugugaaug uuuuccggug cggcgggugu ugcaacgaag agucucugau cuguaugaau      480

acguccacca gcuauauuuc caagcagcuc uuugaaaucu cugugccucu gacaagcguc      540

cccgagcuug ugccugugaa ggucgccaac cauaccggau gcaaaugucu gcccacagcu      600

ccucgccacc cguacuccau cauuagacgg agcauccaga uucccgaaga ggaccgcugc      660

ucucauucca agaaacucug uccuaucgau augcuguggg acagcaauaa gugcaaaugc      720

guucuucaag aggaaaaccc ccuggccggc accgaggauc acucucaccu ccaggaaccu      780

gcucugugug ggccccauau gauguucgac gaggauagau gcgaaugugu gugcaagacg      840

ccguguccua aggaccugau ucagcacccc aaaaauugca gcuguuuuga gugcaaggag      900

ucccucgaaa cauguugcca gaaacauaag cuguuccacc cugauaccug uucuugcgag      960

gaccggugcc ccuuucacac aagacccugu gccagcggaa aaaccgcgug cgccaagcau     1020

ugucgcuucc cuaaagaaaa gcgggcugcc caaggcccgc acuccagaaa gaaccccuga     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  1942
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt6)

<400>  1942
gggagaaagc uuaccaugga cucagacgaa acaggauuug aacacucagg auuaugggua       60

ucaguauuag caggauuacu acucggagca ugccaagcac acccaauccc agacucauca      120

ccauuauuac aauucggagg acaagucaga caacgauacu uauacacaga cgacgcacaa      180

caaacagaag cacauuuaga aauaagagaa gacggaacag uaggcggagc agcagaucaa      240

ucaccagaau cacuacuaca acuaaaagca cuaaaaccag gaguaauaca aauauuagga      300

guaaaaacau caagauucuu augccaaaga ccagacggag cacuauacgg aucauuacac      360

uuugauccag aagcaugcuc uuucagagaa cuacuacuag aagacggaua caacguauac      420

caaucagaag cucauggacu accuuuacac cuaccaggaa acaaaucacc acacagagau      480

ccagcuccca gaggacccgc aagauuccua ccauuaccag gauuaccacc agcauuacca      540

gaaccaccag gaauacuagc accacaacca ccagacguag gaucaucaga cccauuauca      600

augguaggac caucacaagg aagaucacca ucauacgcau cauaaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  1943
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt6)

<400>  1943
gggagaaagc uuaccaugca cucauuucca ccacuauuau uacuacuauu uuggggaguc       60

guaucacaua gcuuucccgc aacacuagaa acccaagaac aagacguaga cuuaguacaa      120

aaauaucuag aaaaauacua uaaccucaaa aacgacggaa gacaagucga aaaaagaaga      180

aacagcggac caguuguaga aaaacuaaaa caaaugcaag aauuuuucgg auuaaaaguu      240

acuggaaaac cagacgcaga aacacuaaaa guaaugaaac aaccaagaug cggaguacca      300

gauguagcac aguucguauu aacagaagga aacccacguu gggaacaaac acaucuuaca      360

uacagaauug aaaauuacac accugaccua ccaagagcag acguagacca cgcaauagaa      420

aaagccuuuc aauuaugguc aaacguaaca ccauuaacau ucacaaaagu uucugaaggg      480

caagcagaca uaaugaucuc auuuguuaga ggagaccacc gagacaauag cccauucgac      540

gggccaggag gaaaccuagc acaugcuuuc caaccaggac cuggaauagg aggcgacgca      600

cauuucgacg aagacgaacg auggacaaac aauuucagag aauacaaccu acauagagua      660

gcagcccacg aauuaggcca cagccuaggc uuaucacacu caacagacau uggagcucua      720

auguacccuu ccuacacauu uucaggagac guacaauuag cccaagacga uauagacgga      780

auacaagcaa uauacggacg aucacaaaac ccaguacaac caauaggacc acaaacacca      840

aaagcaugcg acucaaaauu aacauuugac gccauaacaa caauaagagg agaaguaaug      900

uuuuucaaag accgauuuua uaugagaaca aauccauucu acccagaagu agaauuaaac      960

uuuauaagug uauucuggcc ucaauuacca aacggauuag aagcagcaua ugaauuugca     1020

gacagagacg aaguacgauu cuuuaaagga aauaaauacu gggccguaca aggacaaaac     1080

guauuacaug gauacccaaa agacauauac agcucauucg gguuuccaag aacaguaaaa     1140

cacauagacg ccgcauuauc agaagaaaac acaggcaaaa cauauuuuuu cguagcaaac     1200

aaauacugga gauacgacga auacaaaaga ucaauggacc caggauaucc aaaaaugaua     1260

gcacacgauu ucccuggcau ugggcacaaa guagaugcag uauucaugaa agauggcuuu     1320

uucuacuucu uucacggaac ucgacaauac aaauucgacc caaaaacaaa aagaauacuc     1380

acacuacaaa aagcaaacag uugguucaau uguagaaaaa acuaaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  1944
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt6)

<400>  1944
gggagaaagc uuaccaugca uucauuccca ccacuacuau uauuauuauu cuggggagua       60

guaucacauu cauuuguacu aacugaagga aauccuagau gggaacaaac ucacuuaacc      120

uauagaauag aaaacuauac accagaccua ccaagagccg acgucgacca cgcaauugaa      180

aaagcauucc aauuauggag uaacguaaca ccacuaacau ucacaaaagu aucagaagga      240

caagcagaca uaaugauauc auuugucaga ggagaccacc gagacaacuc accauuugac      300

ggaccuggag gaaaucucgc acacgcauuc caaccaggac caggaauagg aggagacgca      360

cauuuugaug aagaugaacg auggaccaac aauuuuagag aauacaaccu acaccgagua      420

gccgcacacg aacucggaca cagccuagga cuaucacacu caaccgacau cggagcacua      480

auguacccau cauacacauu cuccggagac guccaacuag cucaagacga cauagacgga      540

auacaagcaa uauacggaag aucacaaaau ccuguacaac caauaggacc acaaacccca      600

aaagcaugcg acucaaaauu aacauuugac gcaauaacca caauuagagg ugaaguaaug      660

uuuuucaaag auagauuuua caugagaaca aaucccuucu auccagaagu agaauuaaau      720

uucauaucag uauucuggcc acaacuacca aauggauuag aagcagcaua cgaauuugca      780

gauagagacg aaguaagauu cuucaaaggc aacaaauacu gggcaguaca aggccaaaac      840

guacuacacg gauauccuaa agacauauac ucuuccuuug gauuuccuag aacaguaaaa      900

cacauagaug ccgcacuauc agaagaaaac accggaaaaa cauacuucuu cgucgccaau      960

aaauacugga gauacgacga auauaaacga ucaauggacc cagguuaccc aaaaaugaua     1020

gcacacgauu ucccaggaau aggacacaaa guugacgcag ucuuuaugaa agacggauuu     1080

uucuacuucu uucacggaac acgacaauac aaauucgauc ccaaaacuaa aagaauccua     1140

acuuuacaaa aagccaauuc uugguuuaau uguagaaaaa acuaaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  1945
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt6)

<400>  1945
gggagaaagc uuaccaugaa aaaaaacaua cucaaaauuc uaauggacuc auacucgaaa       60

gaaucaaaaa uacaaacagu ccgcagaguu acaucagucu cguuacuagc aguauaccug      120

acgaugaaca cauccucguu aguacucgcu aaaccuauag aaaauaccaa cgauaccagu      180

auaaaaaacg uagaaaaauu aagaaaugca ccaaacgaag aaaacaguaa aaaaguagaa      240

gacaguaaaa augacaaagu agaacaugua aaaaacauag aagaagcaaa aguugaacaa      300

guagcaccag agguaaaauc caaaagcaca uuaagaagcg cgucaaucgc caacacaaau      360

ucagagaagu acgacuucga auacuuaaac ggauuaaguu auacagaacu aacaaaucuc      420

auuaaaaaua ucaaauggaa ccagauaaau ggacuauuua auuacucaac aggaucacaa      480

aaauuuuucg gagacaaaaa uagaguacaa gcaauuauaa acgcuuuaca agaaagcgga      540

cgaacguaua cagcaaacga uaugaaagga auugaaacau ucacagaagu acuacgcgcu      600

gguuuuuauc ugggcuauua uaacgacgga cuaucauacc ucaacgaccg aaacuuccaa      660

gauaaaugca uaccagcgau gauugcaauu caaaaaaacc caaacuuuaa acuaggaacc      720

gcaguccaag augaaguaau aacgucgcuc ggaaaacuaa uaggaaaugc aagcgcuaau      780

gcagaaguug uaaauaacug uguucccgua cuaaaacaau uccgagaaaa uuuaaaucaa      840

uacgcaccag auuacgucaa aggaacggcc guuaaugaac uuaucaaagg aauagaauuu      900

gauuucucag gagcagcuua ugaaaaagac guaaagacua ugccauggua cggaaaaaua      960

gaucccuuua uaaaugagcu gaaggcacua ggccuuuacg gaaacaucac aucagcuaca     1020

gaaugggcgu cagaugucgg gauauacuau cuaucaaaau ucggacuuua cucaaccaac     1080

cgaaaugaua uaguacaauc cuuagaaaaa gcaguagaua uguauaaaua cggaaaaaua     1140

gcuuucgucg caauggaacg aaucacaugg gauuaugacg guauaggaag caauggaaaa     1200

aaaguagauc augacaaauu ccuagaugac gcagaaaaac auuaccuccc caaaacauac     1260

accuucgaua acggcacauu cauaauaaga gcuggagaca aaguaucaga agaaaaaauc     1320

aaacguuuau acugggcauc acgagagguu aaaucacaau uccauagagu agucgguaau     1380

gacaaagcau uagaaguagg caaugcagac gacguacuca caaugaaaau auucaauucu     1440

ccugaagaau auaaauuuaa uaccaacauu aacggaguau cuacagacaa uggaggccuu     1500

uacauagaac caagaggaac guucuauacc uacgaaagaa caccacaaca aucaaucuuu     1560

ucauuagaag aacuauuuag acacgaauac acacacuauc ugcaagcacg auaccuggug     1620

gauggacuau ggggacaagg gccauuuuau gaaaaaaacc gcuuaacaug guuugaugaa     1680

ggcacagccg aauuuuucgc aggaucaacc agaacaucgg gugucuuacc acggaaauca     1740

auacucgggu acuuagcaaa agacaaagua gaucauagau auucauuaaa aaaaacacua     1800

aauaguggau augaugacuc ggauuggaug uuuuacaacu augguuuugc gguagcacau     1860

uauuuauaug aaaaagauau gcccacauuc auaaaaauga acaaagcuau auuaaauacc     1920

gauguaaaga gcuaugauga aauaauaaaa aaacucagug augaugcaaa uaaaaacacu     1980

gaauaucaaa accacauaca agaacuagca gacaaauacc aaggagcagg uauuccguua     2040

guuucagaug auuacuuaaa agaccacgga uauaaaaaag caucagaagu auacagugaa     2100

auaucgaaag cagccagccu uacaaacacc ucaguaacag cagagaaaag ucaauauuuc     2160

aacacauuua cacuaagagg aacauacacg ggggaaaccu caaaaggaga auuuaaagau     2220

ugggaugaaa uguccaaaaa acuagacgga acacuagaga gcuuagcuaa aaacaguugg     2280

agcggauaca aaacuuuaac ggcauacuuu acuaacuacc gaguuacaag ugacaauaag     2340

guucaauacg acguaguauu ucacggagua cuaacagaca acgcugauau uaguaacaac     2400

aaagcgccua ucgcuaaagu aacaggacca ucgacugggg cagucggaag gaacauagaa     2460

uuuucuggga aagacaguaa agaugaagac ggaaaaauag uuaguuacga uugggauuuu     2520

ggcgauggag cuaccucucg uggaaagaac ucugugcaug cauacaaaaa agcaggaaca     2580

uauaacguaa cccuaaaagu aacagacgac aaaggagcaa cagcuacaga gagcuuuacc     2640

auagaaauaa aaaacgaaga uacaacgaca ccaauaacaa aagagaugga accuaaugau     2700

gacauaaaag aagcuaacgg acccauagug gaaggaguaa cagugaaagg agaccugaau     2760

ggcagcgaug acgcugauac uuuuuauuuc gaugucaaag aagacgguga cguaaccauu     2820

gaacuaccgu acagcggcag uucaaauuuu acaugguugg uauauaaaga aggagacgac     2880

caaaaccaca uagcaucugg aauagauaaa aauaacucaa aaguugguac auuuaaaagu     2940

acaaaaggua gacacuaugu auucaucuau aaacacgaca gcgcaucaaa cauauccuau     3000

ucccucaaua uaaagggacu aggaaaugaa aaacugaaag aaaaagaaaa uaacgauucc     3060

agugacaaag caacuguaau cccaaauuuu aauacaacaa ugcaaggauc uuuauuagga     3120

gacgauaguc gcgacuauua cucauuugaa gugaaagaag aaggagaagu aaauauagaa     3180

cuugacaaaa aagacgaguu cggaguaacc uggacucucc acccagaauc aaauauaaac     3240

gauagaauca cauacggaca aguagacggu aacaaagucu caaauaaggu aaaacuuaga     3300

ccagggaaau acuauuuacu cguauauaaa uacucuggca gcggcaacua cgaguuacgg     3360

guuaacaaau aaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  1946
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt6)

<400>  1946
gggagaaagc uuaccaugaa augggucacc uuuauaaguc uacuuuucuu auuuuccuca       60

gcauauagca uagcaaauac aaauuccgaa aaauaugacu ucgaauaccu aaacggucuu      120

aguuacacag aauuaacuaa ccuaauuaaa aacauaaaau ggaaucaaau aaauggcuua      180

uuuaauuauu caacagguag ucaaaaauuc uucggagaua aaaacagagu gcaagcaaua      240

auaaacgccc uacaagaguc aggacgaaca uauacagcaa augacaugaa aggaauagag      300

acauucacag agguauuacg ugccggauuc uaccuaggau acuacaacga cgguuuaucu      360

uacuuaaaug acagaaacuu ccaggauaaa uguauaccag caaugauagc aauacagaaa      420

aacccuaauu ucaaacucgg aacggcgguu caagacgaag uaauuacauc uuuagguaaa      480

uugauaggaa acgcaucagc gaacgccgag guaguaaaca auugcguacc gguccuuaaa      540

caauuuagag aaaaucuaaa ccaauaugca ccagacuacg ugaaaggaac agcagugaau      600

gaauuaauaa aaggcauuga guucgacuuc ucaggagcag cauaugaaaa agauguaaaa      660

acaaugccau gguacggaaa aauagaucca uucauaaaug aacuaaaagc auuaggauua      720

uacggcaaca ucaccagugc aacugaaugg gcaucagaug ucgggauaua cuauuuauca      780

aaauucggac ucuauagcac aaaccgaaac gacauaguac aaucacuaga gaaagcagua      840

gacauguaca aauacgggaa aauagcauuu guagccaugg aacgaauuac augggacuac      900

gauggcauag guagcaaugg aaagaaagua gaucacgaua aauuccuuga cgacgcagaa      960

aaacacuauc uuccuaaaac auacacuuuu gauaacggua ccuucauaau acgagccggu     1020

gauaaaguaa gcgaagagaa aauaaaaagg cuauauuggg caagcagaga agucaaaagc     1080

caauuucaua gaguaguagg aaaugacaaa gcacuagaag uuggaaacgc ugacgauguu     1140

cuaacaauga aaaucuucaa cucaccugaa gaauacaaau ucaacacaaa cauaaaugga     1200

guaaguaccg acaacggagg auuauauaua gaacccaggg ggacguuuua uaccuacgag     1260

agaaccccuc aacaaucuau auuuuccuua gaagaauuau uucgacauga auacacacac     1320

uauuuacaag cacgauauuu gguagaugga cuauggggac aaggaccauu uuaugagaaa     1380

aacagacuua cgugguucga cgaaggaacg gcagaguucu uugcaggaag uacaagaaca     1440

aguggaguau uaccaagaaa aucaauacua gguuacuuag caaaagacaa aguagaucac     1500

agauacagcc uaaagaaaac acugaauagc gguuaugaug acagugauug gauguucuau     1560

aauuacggau ucgcaguagc ucacuaucua uaugaaaaag auaugccaac auucaucaaa     1620

augaauaaag caauacuuaa caccgacguu aaaucauaug acgaaauaau aaagaaauua     1680

agugacgacg caaacaaaaa uaccgaauac caaaaccaca uccaagaacu agcagacaaa     1740

uaucaaggug caggaauacc auuaguauca gacgacuacc ucaaagacca uggauacaag     1800

aaagcguccg aaguauacuc agaaauaagu aaagcagcau cauugacuaa uacuucagua     1860

acagcagaaa aaucacaaua cuuuaacaca uucacacuuc gcggaacaua uacgggagaa     1920

accucaaaag gugaauuuaa agauugggac gaaaugagua aaaagcucga cggcacucua     1980

gaaucauugg cuaaaaacuc cuggucagga uauaaaacac uaacagccua cuucaccaau     2040

uacagaguca ccucagauaa uaaaguacaa uaugacguag uauuucaugg agucuuaaca     2100

gacaacgcug auauaaguaa caauaaagcg ccuauagcga aaguaacagg accaucaacg     2160

ggagcaguag gaagaaauau ugaguucuca ggaaaggaua gcaaagacga agacggaaaa     2220

auuguaucuu augauuggga uuucggagau ggagcaaccu caagagggaa aaacagugug     2280

caugccuaca agaaagcagg aacuuauaau guaacacuaa aagugacaga ugacaaagga     2340

gcgacagcaa cagagagcuu cacgauugaa auuaaaaacg aagauacuac aacacccaua     2400

acaaaagaaa uggaaccaaa ugaugacaua aaagaagcaa acggaccgau aguggaaggc     2460

guaacgguaa aaggagacuu aaauggaagu gaugacgccg acacauuuua cuuugauguu     2520

aaagaagacg gugaugucac aauagaauua cccuacucug guaguuccaa cuucacuugg     2580

uuaguauaca aagaaggaga ugaucaaaau cauauagcau ccggaauaga caaaaacaau     2640

agcaaaguag gcacauuuaa auccacaaaa ggacgucauu auguuuucau uuacaaacac     2700

gauagugcaa guaacauaag uuauucucua aauauaaaag gacuagguaa ugaaaaacua     2760

aaagaaaaag aaaacaacga uagcagugac aaagcuacug uuaucccaaa cuucaacacc     2820

acaaugcaag gcagcuuacu cggagacgau ucacgagauu auuacagcuu cgaaguaaaa     2880

gaagaggggg aaguaaacau agaacuagau aagaaagacg aauuuggagu aacauggaca     2940

cuacacccgg aaucgaacau aaaugacaga aucacauaug gacaaguaga cggaaacaaa     3000

guaucaaaua aagucaaacu aagaccuggc aaauauuacc uauuagugua uaaauauuca     3060

ggaucaggua auuacgaacu gagagucaau aaauaaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  1947
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt6)

<400>  1947
gggagaaagc uuaccaugaa guggguaacu uucauaaguc uucuuuuccu uuucucuuca       60

gcauacucga ugaagaaaaa cauacuaaaa auacucaugg auuccuauag caaagaaagu      120

aaaauacaaa caguacggag aguuacauca guaagucuau uagcaguaua ccuaacaaug      180

aauacaagcu ccuuaguauu agcaaagcca aucgaaaaca caaacgauac gucaauuaaa      240

aacguagaaa aauuacgaaa cgcaccuaau gaagaaaacu caaagaaagu cgaagacagc      300

aaaaacgaua aagucgagca cgugaaaaau auagaagaag caaaaguaga acaaguagcc      360

ccagaaguaa aaaguaaauc aacucuaaga ucugcuucac gcagacgacg uaaacgaaua      420

gccaacacaa auucagaaaa auaugauuuc gaauaccuaa acggguuauc auacacagag      480

cuaacgaauc uaaucaaaaa cauaaaaugg aaccaaauaa auggccuauu uaauuauagc      540

acaggauccc aaaaauucuu cggcgacaaa aaucgaguac aagcaauaau uaaugcacua      600

caggaaucug gcagaacaua uacugcuaau gacaugaaag gaauagaaac auuuacagaa      660

guacucagag caggauuuua uuuagguuau uauaaugacg gcuuaaguua ccuaaaugau      720

agaaacuuuc aagauaaaug cauaccugca augaucgcaa uacagaaaaa cccaaacuuu      780

aaacuaggga cagcgguaca agacgaagua auaaccagcu uaggaaaacu caucggaaac      840

gcuucugcaa acgcggaagu uguaaacaac ugcguaccag uacuaaaaca auuccgagaa      900

aaccuaaauc aauacgcucc agauuaugua aaaggaacgg cuguaaacga auuaauaaaa      960

gguaucgaau uugauuucag cggcgcagcc uaugaaaagg acgucaaaac gaugccaugg     1020

uauggaaaaa uagacccauu cauaaaugaa cugaaagcac ucggacuuua cgguaauaua     1080

acaagugcua cagaaugggc aucagacgua ggaauauauu auuuaucaaa auucggauua     1140

uacucaacaa auagaaauga cauaguacaa agucuagaaa aagcggucga cauguacaaa     1200

uauggcaaaa uagcauuugu agcuauggaa cgcauaacau gggacuauga uggaauaggu     1260

ucuaacggua agaaaguuga ucaugauaaa uucuuagaug acgcagaaaa acacuacuua     1320

ccaaaaacau auacauucga caacggcacc uuuauaauac gugccggaga caaaguuagu     1380

gaagagaaaa uuaaacgacu auacugggcu ucgagagaag uaaaaucuca auuucacaga     1440

gucgugggaa acgauaaagc acuagaaguu ggaaacgcag augauguccu cacaaugaaa     1500

aucuuuaauu ccccggaaga auacaaauuu aauacgaaua ucaacggcgu gucaacugau     1560

aauggaggac uguauauaga accacgagga acauucuaca cuuaugaaag aaccccgcaa     1620

caaagcauuu ucucccuaga agaacuauuc aggcaugaau auacacauua ccuccaagcc     1680

agauaccuag uugauggacu auggggacaa ggaccguuuu acgagaaaaa ucgauuaacc     1740

ugguuugaug aaggaacggc agaguucuuu gcaggaucaa caagaacaag cggaguacua     1800

ccaagaaaau ccauacuagg uuacuuagca aaagauaaag uugaccacag auauaguuua     1860

aagaaaaccc ucaacagugg uuacgaugau ucggauugga uguuuuacaa cuacggauuc     1920

gcaguugcgc acuacuuaua cgaaaaagau augccaacgu ucauaaaaau gaacaaagca     1980

auacuaaaua cugaugucaa aagcuacgau gaaauaauaa agaaacuaag ugacgacgcc     2040

aauaaaaaua cagaauacca aaaccauaua caagaacuag cugacaaaua ccaaggugcg     2100

ggaauaccuc uaguaaguga cgacuaucua aaagaucaug gauauaagaa agcaucagaa     2160

guuuacucug aaaucagcaa agccgcauca uuaacaaaca ccucaguaac agcugaaaaa     2220

ucacaauauu ucaacacauu cacacuaagg gguacauaua caggcgaaac caguaaagga     2280

gaauuuaaag auugggacga aaugagcaag aaauuagaug gaacucuaga aucuuuagcc     2340

aaaaacucuu ggucaggaua caaaacauua acggcauauu ucacgaacua uagaguuaca     2400

agugauaaua aagugcaaua ugacguagua uuucacggag uccucacaga uaacgccgau     2460

auuucaaaua auaaagcucc gauagcuaaa guaaccgguc cauccacagg agcaguaggc     2520

agaaacauug aguucucugg uaaagauagu aaagaugaag auggaaaaau agucucauac     2580

gacugggauu ucggagaugg agcaacauca agagggaaaa acucaguaca ugccuauaag     2640

aaagcgggaa ccuauaacgu aacccuaaaa gucacagaug acaagggagc aacggcuaca     2700

gaaaguuuua caaucgaaau uaaaaaugaa gacacaacaa caccaauaac gaaggaaaug     2760

gaaccaaacg acgacaucaa agaagcuaac ggaccaauag uugaaggagu aacaguuaaa     2820

ggagauuuaa acggaucaga ugaugcggac acuuuuuacu ucgaugucaa agaagaugga     2880

gacgucacca uugaauuacc uuauucagga agcaguaacu ucaccugguu aguauauaaa     2940

gaaggagacg aucaaaacca caucgcuagc ggcauagaua aaaauaauuc aaagguugga     3000

accuuuaagu caacaaaagg aagacacuau guauuuaucu acaaacauga uuccgccuca     3060

aacauauccu auagccugaa uaucaaaggc cuaggaaacg aaaaauuaaa agaaaaagaa     3120

aauaacgaca gcucagauaa agcaacagua auuccuaacu uuaacacuac aaugcaaggu     3180

agccuauugg gugacgauag uagagacuau uacagcuuug aagucaaaga agaaggagaa     3240

guuaauauag aacuagacaa gaaagaugag uuuggaguaa ccuggacauu gcacccugaa     3300

uccaauauaa augacagaau uacuuauggc caagucgacg gaaauaaagu cucaaacaaa     3360

gugaaacuaa gaccggguaa auauuaccuu uugguguaca aauauagugg cucaggaaac     3420

uaugaauuaa gggucaacaa augaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  1948
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt6)

<400>  1948
gggagaaagc uuaccaugaa cuuucucaaa auaauacuga accguggcaa aacaaugaaa       60

agaaaaugcc uaaguaaaag acucaugcug gccaucacaa uggcuacaau auucaccguc      120

aacagcaccu uaccuauuua ugcagccgua gacaaaaaua acgcuacugc cgccguacaa      180

aaugaaagca aaagauacac ugucucguau cuuaaaacac uaaauuacua cgaccuagua      240

gauuuauuag uaaaaacaga aauagaaaac cuaccugauc ucuuucaaua cucaucagau      300

gccaaagaau uuuacggaaa caaaacacga augucuuuua uaauggauga aauaggccgc      360

agagcuccac aauacaccga aaucgaccac aaaggaauac caacauuagu ggaaguggua      420

agagcaggau uuuauuuagg cuuccacaac aaagaacuaa acgaaauaaa uaaaagaucc      480

uucaaggaaa ggguaauacc cucaauauua gcaauacaga aaaaccccaa uuucaaacua      540

ggaacagaag ugcaagacaa aaucgucagc gcaacgggac uucuagccgg uaacgaaacu      600

gcuccaccag aaguaguaaa caacuucacc ccaauccuac aagacuguau uaaaaacaua      660

gacagauaug cauuagacga ucuaaaguca aaggcuuuau uuaacgucuu agcugcaccu      720

acuuacgaca uaacagaaua ccucagggca acaaaagaaa aaccggaaaa uacaccuugg      780

uacggaaaaa uagauggcuu cauaaacgaa cuaaagaaau uagccuuaua cggaaaaauu      840

aacgauaaua acucuuggau aauagauaau gguauuuacc acauagcucc guuagggaaa      900

cugcauagua acaauaaaau cggaauagaa acauuaaccg aagucaugaa aguauaccca      960

uauuuaucaa ugcaacacuu acaauccgcc gaccaaauca aaagacacua cgacagcaaa     1020

gaugcagaag gaaauaaaau accauuagau aaauucaaga aagaaggaaa agaaaaauac     1080

ugcccaaaaa ccuauacuuu cgacgaugga aaaguaauaa uaaaagcugg agcaagaguc     1140

gaagaagaaa aaguaaaacg acucuacugg gcaucaaaag aagucaacuc acaauucuuc     1200

agagucuaug gcauagauaa accgcuagaa gagggaaacc ccgaugacau ccuaacaaug     1260

guaauauaca auucaccaga agaguauaaa cuaaauagcg uauuauacgg auacgacaca     1320

aauaacggcg gaauguacau cgaaccugaa ggaaccuucu ucaccuauga gcgagaagcc     1380

caagaaagua cauacacccu ggaagaacua uucagacaug aauacacaca uuaccuacaa     1440

ggacgauacg ccgugccagg acaauggggg cgaacgaaau uauacgacaa cgacagacuc     1500

acaugguaug aagaaggugg agcagaauua uucgcaggca guacccguac aucagguauc     1560

cuaccaagaa aaucuaucgu caguaacaua cacaacacaa cuaggaauaa ucgauacaaa     1620

uuaucagaca caguacauuc caaauacggg gccuccuucg aauuuuacaa cuacgcgugc     1680

auguuuaugg auuauaugua uaacaaagau auggguauuc uaaacaaauu aaacgaccua     1740

gccaagaaua augacgugga cggauacgac aacuauauua gggaccuauc aucaaauuau     1800

gcauuaaacg acaaauacca agaccacaug caagagagga uagauaauua cgaaaaccua     1860

acaguaccau uugucgcaga cgauuauuua gugcgacaug cauacaaaaa uccaaacgaa     1920

aucuacagug agauuucaga gguagcaaaa cucaaggaug cgaaauccga agucaagaaa     1980

agucaauacu ucaguacauu cacgcuaaga ggaucauaua caggaggagc cucaaaagga     2040

aaauuagaag accaaaaagc aaugaauaaa uucauagacg auucauuaaa gaaacuagau     2100

accuacaguu ggaguggcua uaaaacacuc acugcauauu ucacaaauua caaaguagac     2160

ucaucuaaua ggguaaccua cgauguagua uuccacggau accucccaaa ugaaggcgac     2220

agcaaaaacu cucucccaua cggaaaaaua aacgggacau acaaagguac ugaaaaagag     2280

aaaaucaaau ucagcagcga aggauccuuc gacccagacg gaaaaauugu uaguuaugaa     2340

ugggacuucg gagauggaaa caaaaguaau gaagaaaacc cagaacauuc cuaugacaaa     2400

gucgggacuu acaccguaaa auuaaaaguu acagaugaua aaggcgaauc caguguauca     2460

acaacaacag ccgaaaucaa agacuuaagc gaaaauaaac uuccaguaau auauaugcac     2520

guaccaaaau cuggagcacu uaaccaaaaa guaguauucu acgguaaagg uacauacgau     2580

ccagacggau caauagcugg guaucaaugg gacuuuggag acgguucaga uuucucauca     2640

gaacaaaauc ccucccacgu auacacaaag aaaggugaau acacagugac acuaagaguc     2700

auggauagca gcggccaaau gucagagaaa acaaugaaaa ucaaaauaac ugaucccgua     2760

uauccaauag gcacagaaaa agaaccaaac aacagcaaag aaacagccag cggaccaaua     2820

guaccaggca uacccgucag uggaacuaua gaaaauacau ccgaccaaga cuacuuuuac     2880

uucgauguaa uaaccccugg agaaguaaaa auagacauaa acaaauuagg uuaugggggc     2940

gcaacauggg uaguguacga ugaaaauaau aacgcaguaa guuaugcuac agacgacggc     3000

caaaaucuau ccggaaaauu caaagcagac aaaccaggca gauacuauau ucaucuauau     3060

auguuuaacg guagcuacau gccuuacagg aucaacauag aaggaagcgu agguagauag     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  1949
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt6)

<400>  1949
gggagaaagc uuaccaugaa acguaaaugc cuuucaaaac gucuaauguu ggcaauuacu       60

auggcaacaa uauuuacagu uaauuccaca cuaccaauau augcagcugu agacaaaaac      120

aaugccacag ccgcaguaca aaaugaaucc aaaagguaca cugucaguua ucuaaaaacu      180

cuuaacuauu acgaccuagu ugaccuauua guaaaaacag aaauagaaaa ccuaccagac      240

uuauuccaau acucaucuga ugcuaaagaa uuuuacggaa auaaaacccg caugaguuuu      300

aucauggaug aaauaggaag acgagcgccu caauauacug aaaucgauca caaaggaaua      360

ccgacgcuag uagaaguugu aagagccggu uuuuacuuag gcuuucacaa caaagaacua      420

aacgaaauaa auaaacgauc auuuaaagag agaguaauac ccagcauccu ugccauacaa      480

aagaauccaa acuucaaauu aggaacagag guacaagaca aaauaguauc cgccacaggc      540

cuauuagcag gaaaugagac agcacccccu gagguaguga acaauuucac accaauauua      600

caagauugca uuaaaaauau agauagauau gcucuagaug aucuaaaauc aaaagcacua      660

uucaacguac uagcagcacc cacauacgau auaacagaau acuuacgagc gaccaaagaa      720

aaaccagaaa acacaccaug guacggaaaa auagacggcu uuauaaauga guuaaagaaa      780

uuagcauuau augguaaaau aaaugauaau aacagcugga uuauagacaa cgggauauau      840

cauauagcac cccuaggaaa acuacacuca aacaauaaaa uaggaauaga aacauuaacc      900

gaagucauga aaguuuaucc uuacuuaucc augcaacacu uacaaucagc agaucaaaua      960

aaaagacauu augauucaaa agacgcagaa gguaacaaaa uaccccuaga caaauuuaag     1020

aaagaaggaa aagaaaaaua uugcccaaaa acauacacau uugacgacgg gaaaguaauc     1080

auaaaagcag gagcgagagu cgaagaagaa aaaguaaaaa gacucuacug ggcaucuaaa     1140

gaaguaaacu cccaauucuu caggguauau ggaauagaca aaccauuaga agaaggaaau     1200

cccgaugaca uuuugacaau gguaaucuau aauaguccgg aagaauauaa acugaacagu     1260

gucuuauacg gauaugauac caacaacggu ggaauguaua uagaaccaga gggaaccuuc     1320

uucaccuaug aaagggaagc ccaagaauca acauacacuc ucgaggaacu auuuaggcac     1380

gaauauacac acuauuuaca aggacgauac gcaguaccag gacaaugggg caggacaaaa     1440

cuuuacgaua acgacagacu aacuugguau gaagaaggug gcgccgaacu auucgccggu     1500

ucaacucgca caagcggaau auugccacga aaaucaaucg uaucuaacau acacaacaca     1560

acaagaaaua accguuacaa acuaucagau acaguucacu ccaaauacgg agcaaguuuu     1620

gaauuuuaca acuacgccug uauguuuaug gacuacaugu auaauaaaga uaugggcaua     1680

cuaaauaaac ugaacgauuu agcuaaaaac aaugacguag acggcuacga caacuacaua     1740

agagauuuaa guuccaacua ugcacuaaau gauaaauauc aagaucacau gcaagaaaga     1800

auagauaacu augaaaauuu aacaguaccu uuuguggcag acgauuaccu uguucgacac     1860

gcauauaaaa accccaauga gauauauuca gaaauuucag aaguagcaaa auuaaaagau     1920

gcaaaaagcg aaguaaagaa aagccaauac uucuccacau uuacccuccg aggaucauac     1980

accggcggag ccuccaaagg aaaacuagaa gaccaaaaag cuaugaacaa auucauagau     2040

gacucccuaa agaaauuaga cacauauuca ugguccggau acaaaacccu aacggcuuac     2100

uucacaaauu acaaagucga cuccucaaau aggguuacau acgacgucgu auuucacgga     2160

uaucucccca augagggaga caguaaaaau ucccuaccau acgggaaaau aaacggaaca     2220

uauaaaggga cagaaaaaga gaaaauaaaa uucucgucug aaggaucuuu ugaccccgac     2280

gggaaaauug ugucauauga augggauuuu ggagauggaa auaaaucaaa ugaagaaaac     2340

ccagaacaca gcuaugacaa aguaggcaca uacaccguaa aauuaaaagu aacagacgac     2400

aaaggagaau caucaguauc caccaccaca gcagaaauua aagaucuauc ugaaaacaaa     2460

cucccaguaa ucuauaugca cguaccuaaa aguggcgcuc ucaaucaaaa aguaguauuu     2520

uacggaaaag gaacauauga cccagacgga agcauagcag gguaucaaug ggauuucgga     2580

gauggaucug auuuuucuuc agaacaaaac ccaucgcacg uauacaccaa gaaaggagaa     2640

uauacaguaa cacuaagagu uauggauuca ucuggacaaa ugucugagaa aacuaugaaa     2700

auaaaaauaa cagacccagu uuauccaaua ggcacagaaa aagaaccaaa caacaguaaa     2760

gaaacagcau caggaccaau cgucccgggc auaccaguaa guggaacaau agaaaauaca     2820

agcgaccaag auuacuucua cuucgaugua auaacaccag gcgaaguuaa aauugacaua     2880

aacaaacucg gauauggagg agcaacaugg guaguauaug augaaaacaa uaaugccgua     2940

ucuuacgcca cagacgaugg acaaaaccua aguggaaaau uuaaagcuga uaaacccgga     3000

cgcuacuaca uacaccugua uauguuuaac gguucauaca ugccauacag gauaaacaua     3060

gaagggagug ugggaagaua aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  1950
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt6)

<400>  1950
gggagaaagc uuaccaugaa auggguuacu uuuauaucau uacuauuccu auucucauca       60

gcauacagcg uacagaacga aucaaaaaga uacacaguaa guuacuuaaa aacguuaaac      120

uacuacgacc uaguagauuu auuagucaaa accgaaauug aaaauuuacc cgaccuuuuc      180

caauacucuu ccgaugcaaa agaauuuuac ggcaauaaaa cacgaaugag cuucauaaug      240

gaugaaaucg guagacgagc uccccaauac acagaaauag accacaaagg aaucccuaca      300

uuaguugaag uaguuagagc aggauucuac cuagguuuuc auaacaagga auuaaaugaa      360

auaaauaaac gaucauucaa agaacgagua auaccaucaa uacuugcaau acagaaaaac      420

ccaaacuuua aacuuggaac ugaaguucaa gacaaaauag ugucagcaac aggacuccua      480

gcuggcaaug aaacagcucc accagaagua guaaacaacu uuacaccaau auuacaagau      540

ugcauuaaaa auauagaccg cuacgcuuua gaugaucuaa aaaguaaagc acuauuuaac      600

guacuggcag caccuacuua cgacauaacc gaauaccuac gagcaacaaa agaaaaaccu      660

gaaaacaccc ccugguacgg aaaaauagac ggauuuauca acgaacuaaa gaaauuagca      720

cuuuauggaa aaauuaacga uaauaauucc uggaucaucg acaauggcau auaccauaua      780

gcuccacuag gaaaauuaca cucaaacaac aaaauaggaa uagaaacacu aacggaggua      840

augaaaguau acccauaucu aucaaugcaa caccuacaau cagccgauca aauaaaaaga      900

cauuaugacu caaaagaugc agaaggcaac aaaauaccac uagacaaauu caagaaagaa      960

ggaaaagaaa aauauugucc gaaaacauac accuuugaug auggaaaagu aauuauaaaa     1020

gcuggagcaa gagucgaaga agaaaaaguu aaacgauuau auugggcauc aaaagaagua     1080

aauagucaau uuuuccgcgu cuauggaaua gauaaacccc uugaggaagg aaauccagac     1140

gacauccuaa caaugguaau auauaauuca ccugaagaau acaaauuaaa uucaguacua     1200

uauggauacg acacaaacaa cggaggaaug uacauagaac cagaagguac auucuuuaca     1260

uaugagagag aagcacaaga aagcacauac acucuagaag aacuauucag acacgaguac     1320

acccacuacc uacaaggucg auaugcugua ccaggacaau ggggaaggac aaaacuauac     1380

gauaaugaca gacuaaccug guacgaagaa ggaggagccg aacuauucgc aggaagcaca     1440

cguacaucag guauacuacc aagaaaaucc auagucagca acauacauaa cacgacacgu     1500

aacaacagau acaaauuaag ugacacaguu cauagcaaau auggagcuuc auuugaguuu     1560

uauaacuacg cauguauguu cauggauuac auguacaaca aagacauggg aaucuuaaau     1620

aaacuaaacg auuuagcuaa aaauaaugau guagauggau acgacaacua uauacgcgau     1680

uuaagcagua acuacgcacu aaacgauaaa uaccaagauc acaugcaaga aaggauagac     1740

aacuacgaaa auuuaacagu cccauucguc gcagacgauu accuagucag acacgccuau     1800

aaaaauccua acgaaauaua cucagagauu agcgaggucg caaaauuaaa agacgcaaaa     1860

agugaaguaa agaaaaguca auauuucagu acauuuaccu uaagaggcuc auauacaggc     1920

ggagcaagua aaggaaaauu agaagaucaa aaagcaauga auaaauucau ugaugacagc     1980

cuaaagaaau uagacacaua cucauggucg ggcuacaaaa cccuuaccgc uuacuuuaca     2040

aacuauaaag ucgacaguuc aaacaggguc acauacgacg uuguauucca cggcuacuua     2100

ccaaaugaag gagacaguaa aaacucccua ccauacggaa aaauaaaugg aacguauaaa     2160

ggaacagaaa aagagaaaau aaaauucuca ucagaaggau cauucgaccc ggacggaaaa     2220

auuguuuccu acgaauggga cuucggggac gguaacaaau cgaacgaaga aaauccugaa     2280

cauucauaug auaaaguagg aacauacaca guaaaacuaa aagucacaga ugacaaagga     2340

gaaucguccg uaucuaccac aacagcggaa auaaaagauu uaucagaaaa uaaacuaccc     2400

guuauuuaca ugcauguccc aaaaagcgga gcauuaaacc aaaaaguagu auuuuacgga     2460

aaaggcacau augauccaga cggaucaauu gccgguuauc aaugggacuu cggagacgga     2520

agcgacuuca guagugaaca aaaccccucc cauguauaca caaagaaagg ugaauacaca     2580

gucaccuuaa gaguaaugga cucaucagga cagaugagug agaaaacaau gaaaauaaaa     2640

auaaccgacc ccgucuaucc aauaggaacc gaaaaagaac caaauaauuc aaaagaaaca     2700

gcaucaggac caauaguacc cggcauccca guaucuggca ccaucgaaaa caccucugau     2760

caagacuacu ucuacuucga cguaauaaca ccaggugaag uaaaaauuga uaucaauaaa     2820

cuaggauacg gcggagcaac auggguaguu uacgacgaaa acaacaacgc aguuagcuac     2880

gcuacagaug acggacaaaa ccuaaguggg aaauuuaaag cagacaaacc uggaagauau     2940

uauauccauc ucuacauguu caacgguucu uauaugccau auagaauaaa cauagaaggc     3000

ucaguaggaa gauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  1951
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt6)

<400>  1951
gggagaaagc uuaccaugaa auggguuaca uucaucagcu uacuauuccu auucaguagc       60

gccuacagca ugaaaagaaa auguuuaucc aaaagacuaa ugcuagcuau cacaauggcu      120

acaauuuuca cagugaacuc uacauuacca auauacgcug caguugauaa aaacaacgca      180

acagccgcua gaagaagaag aaaacgagua caaaacgaaa gcaaaagaua caccgucucu      240

uacuuaaaaa cacuaaauua cuacgaucug guagaccuuc uaguaaaaac ugaaauagaa      300

aaucuaccag acuuauucca auauucaagc gacgcaaaag aauuuuacgg aaacaagaca      360

agaaugaguu uuauuaugga ugaaauugga cguagagcac cccaauacac cgaaauagau      420

cacaaaggca uacccaccuu aguggaaguu guaagagccg gguucuacuu aggauuucau      480

aauaaagaau uaaaugaaau aaauaaacga uccuucaaag aaagagucau accaagcauu      540

cucgcaauuc agaaaaaccc aaauuucaaa cuaggaaccg aaguacaaga uaaaauugua      600

ucagcaaccg gauuauuagc ugguaacgaa acagcucccc cugaaguagu aaauaacuuu      660

acccccauau uacaagauug cauuaaaaau auagacagau acgccuuaga cgaccuaaaa      720

ucaaaagcac uauucaaugu ccucgcugcu ccaacauaug acauaacaga auaccuuaga      780

gcgacuaagg aaaaacccga aaacacccca ugguauggua aaauagaugg uuucauaaac      840

gaacuaaaga aacucgcacu auacggaaaa auaaacgaca acaauagcug gauaauagac      900

aauggaauau aucauauagc accauuagga aaacuacauu caaacaauaa aaucggaaua      960

gaaacauuaa cagaaguaau gaaaguauau cccuauuuaa gcaugcaaca ucuacagucu     1020

gcggaccaaa uaaaacguca uuacgacucu aaagacgcag aaggaaacaa aauuccacua     1080

gacaaauuua agaaagaagg gaaagaaaaa uacugcccaa aaaccuacac uuuugaugau     1140

ggaaaaguaa uuauaaaagc uggagcacgc guagaagaag aaaaaguaaa acgauuauac     1200

ugggccagua aagaagugaa uagucaauuc uucagagucu auggaauuga caaaccucua     1260

gaagaaggca acccagacga uauacuaacc augguuauau auaauucucc agaagaauac     1320

aaacuaaauu caguauuaua cggauaugau accaacaacg gagggaugua cauagaaccu     1380

gaagguacuu ucuuuacaua cgaaagagaa gcacaagaaa gcacauauac cuuagaggaa     1440

cuauuuagac acgaauauac acacuaccug caaggaagau augcugugcc aggacaaugg     1500

ggacguacua aacuauacga caacgauaga cuaacauggu augaagaagg aggagcagaa     1560

cucuuugcug gcuccaccag aacaagugga aucuuaccaa gaaaaaguau aguaucaaac     1620

auacauaaca caacaagaaa uaacagauac aaacucagcg acacaguaca cucaaaauac     1680

ggagcuagcu ucgaauuuua uaauuacgca ugcauguuca uggacuacau guacaacaaa     1740

gauaugggaa ucuuaaacaa acuaaaugau cuagcgaaaa auaaugaugu ugaugguuac     1800

gacaacuaua uccgugaucu cucaucaaac uacgcacuga acgacaaaua ccaagaucau     1860

augcaagaac guauagauaa uuaugaaaau uuaacuguac ccuucguagc agaugauuac     1920

uugguuaggc augcauacaa aaauccuaau gaaauauacu cagaaauauc ugaaguagcc     1980

aaacuaaaag augcaaaaag ugaaguuaag aaaagccaau auuuuuccac auuuacauua     2040

cgaggauccu auacuggagg ggccaguaaa gguaaacuag aagaccaaaa agcaaugaac     2100

aaauucaucg augauucccu aaagaaauua gauacauaua guuggucagg cuacaaaaca     2160

cuaacagccu auuuuacaaa uuacaaagua gauucaagca auagaguuac auacgacgua     2220

guauuccaug guuauuuacc aaaugaaggc gacaguaaaa auucauuacc auacggaaaa     2280

auaaauggaa cauauaaagg aacggaaaaa gagaaaauaa aauucuccuc ugaaggaucc     2340

uuugacccag acggaaaaau cguuagcuac gaaugggacu ucggugaugg uaacaaauca     2400

aacgaagaaa acccugaaca cagcuacgac aaaguaggaa ccuacacagu caaacucaaa     2460

guaacagaug auaaagguga aucuucuguu ucuacgacaa cagcagaaau caaagauuua     2520

uccgaaaaca aacucccagu cauauauaug cacguaccaa aaucaggugc acuuaaucaa     2580

aagguuguau uuuauggaaa agguacauau gaucccgacg gaucaaucgc aggauaccaa     2640

ugggacuucg gagacggguc agauuucucc ucugaacaaa acccaagcca cguauacacc     2700

aagaaaggag aauauaccgu aaccuuacga gucauggaua guucagguca aaugucagag     2760

aaaacaauga aaaucaaaau aacugaucca guauacccaa ucggaacaga aaaagaacca     2820

aauaauagca aagaaacagc aaguggaccc aucgugccag gcaucccagu aucgggcaca     2880

auagaaaaua cgagcgacca agacuauuuc uacuuugacg ucauaacacc aggagaagua     2940

aaaaucgaua uaaauaaacu aggauacgga ggagccacau gggucgucua cgaugaaaac     3000

aacaaugccg ugagcuaugc aacagacgau ggacagaauc uuucugggaa auucaaagca     3060

gauaaaccag gacgauacua uauacacuua uacauguuua augguaguua caugccauac     3120

cgaauaaaca uugaaggaag cguuggaaga ugaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  1952
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt6)

<400>  1952
gggagaaagc uuaccauggg uaccuggaua uuauucgcau gccuacuagg cgcagcauuc       60

gccaugccau uaccaccaca cccaggacac ccaggauaca ucaacuucuc auacgaagua      120

cuaacaccac uaaaauggua ccaaucaaua agaccaccau acccaucaua cggauacgaa      180

ccaaugggug gauggcuaca ccaccaaaua auaccaguac uaucacaaca acacccacca      240

acacacacac uacaaccaca ccaucacaua ccaguaguac cagcacaaca accaguaaua      300

ccacaacaac caaugaugcc aguaccagga caacacucca ugacaccaau acaacaucac      360

caaccaaacc uaccaccccc agcacaacaa ccauaccaac cacaaccagu acaaccacaa      420

ccacaccaac caaugcaacc acaaccacca guacacccca ugcaaccacu cccaccacaa      480

ccaccacuac caccaauguu cccaaugcaa cccuuaccac caaugcuacc agaccuaaca      540

cuagaagcau ggcccucaac agacaaaaca aaaagagaag aagucgacua aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  1953
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt6)

<400>  1953
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc auacccauca      120

uacggauacg aaccaauggg aggaugguaa ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  1954
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt6)

<400>  1954
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc accaaugcua      120

ccagaccuaa cacuagaagc auggccauca acagacaaaa caaaaagaga agaaguagac      180

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  1955
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt6)

<400>  1955
gggagaaagc uuaccauggc aguaauggca ccaagaacac uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uacauaaacu ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca      180

ccauacccau cauacggaua cgaaccaaug ggaggauggu aaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  1956
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt6)

<400>  1956
gggagaaagc uuaccauggc aguaauggca ccaagaacau uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uacauaaacu ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca      180

ccaccaaugc uaccagaccu aacacuagaa gcauggccau caacagacaa aacaaaaaga      240

gaagaaguag acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  1957
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt6)

<400>  1957
gggagaaagc uuaccauggg aacauggaua cuauucgcau gcuuaguagg agcagcauuc       60

gccaugccac uaccaccaca ccccggccac ccaggauaca uaaacuucuc auacgaagua      120

uuaacaccac uaaaauggua ccaaucaaug auacgcccac cauacuccuc auacggauac      180

gaaccaaugg gcggcugguu acaccaucaa auaauaccag uaguauccca acaacaccca      240

cuaacacaca cacuacaauc acaccaccac auaccaguag uaccagcaca acaaccacga      300

guacgccaac aagcacuaau gccaguacca ggacaacaau caaugacacc aacacaacac      360

caccaaccaa accuaccauu accagcacaa caaccauucc aaccacaacc aguacaaccc      420

caaccacacc aaccaaugca accacaacca ccaguacaac caaugcaacc acuccuaccc      480

caaccaccac uaccaccaau guucccacua agaccacuac caccaauacu accagaccua      540

caccuagaag cauggccagc aacagacaaa acaaaacaag aagaaguaga cuaaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  1958
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt6)

<400>  1958
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaucaa ugauaagacc accauacuca      120

ucauacggau acgaaccaau gggaggaugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1959
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt6)

<400>  1959
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uauuaacacc acuaaaaugg uaccaaucaa ugauaagacc accaccaaua      120

cuaccagacc uacaccuaga agcauggcca gcaacagaca aaacaaaaca agaagaagua      180

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1960
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt6)

<400>  1960
gggagaaagc uuaccauggc aguaauggca ccaagaacau uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacauccagg acacccagga      120

uauauaaauu ucucauacga aguauuaaca ccacuaaaau gguaucaauc aaugauaaga      180

ccaccauaca gcucauacgg auacgaacca augggaggau gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1961
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt6)

<400>  1961
gggagaaagc uuaccauggc aguaauggca ccaagaacac uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uacauaaacu ucucauacga aguacuaaca ccacuaaaau gguaucaauc aaugauaaga      180

ccaccaccaa uacuaccaga ccuacaccua gaagcauggc cagcaacaga caaaacaaaa      240

caagaagaag uagacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1962
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt6)

<400>  1962
gggagaaagc uuaccauggg aaccuggaua uuauucgcau gccuacuagg agccgcauuc       60

uccaugccac uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua      120

uuaaccccau uaaaauggua ucaaaacaug auaagacacc cauacacauc auacggauac      180

gaaccaaugg gaggauggcu acaccaccaa auaauaccag uaguauccca acaaacacca      240

caaucacacg cacuacaacc acaccaccau auaccaaugg uaccagcaca acaaccagga      300

auaccacaac aaccaaugau gccacuacca ggacaacacu caaugacacc aacacaacac      360

caccaaccaa accuaccacu accagcccaa caaccauucc aaccacaacc aguacaacca      420

caaccacacc aaccacuaca accccaaucc ccaaugcacc caauacaacc acuacuacca      480

caaccaccac uacccccaau guucucaaug caaucacuac uaccagaccu accacuagaa      540

gcauggccag ccacagacaa aacaaaaaga gaagaaguag acuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1963
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt6)

<400>  1963
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaaaua ugauaagaca cccauacaca      120

ucauacggau acgaaccaau gggaggaugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  1964
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt6)

<400>  1964
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaaaca ugauaagaca cccaucacua      120

cuaccagacc uaccacuaga agcauggcca gcaacagaca aaacaaaaag agaagaagua      180

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  1965
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt6)

<400>  1965
gggagaaagc uuaccauggc aguaauggca ccaagaacau uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacauccagg acacccagga      120

uauauaaauu ucucauacga aguauuaaca ccacuaaaau gguaucaaaa uaugauaaga      180

cauccauaua caucauacgg auacgaacca augggaggau gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  1966
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt6)

<400>  1966
gggagaaagc uuaccauggc aguaauggca ccaagaacac uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uacauaaacu ucucauacga aguacuaaca ccacuaaaau gguaccaaaa caugauaaga      180

cacccaucac uacuaccaga ccuaccacua gaagcauggc cagcaacaga caaaacaaaa      240

agagaagaag uagacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  1967
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt6)

<400>  1967
gggagaaagc uuaccauggg aacauggaua cuauucgcau gccuacucgg ugcagcauuc       60

ucaaugccac uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacauacga      120

cacccauaca caucauacgg auacgaacca augggaggau ggcuacacca ccaaauaaua      180

cccguaguau cucaacaaac accacaauca cacgcacuac aaccacacca ccacauacca      240

augguaccag cacaacaacc aggaauacca caacaaccaa ugaugccauu accaggacaa      300

cacucaauga caccaacaca acaccaccaa ccaaaccuac cacuaccagc acaacaaccu      360

uuccaaccac aaccaguaca accacaacca caccaaccac uacaaccaca aucaccaaug      420

cacccaauac aaccauuacu accacaacca ccacuaccac caauguucuc aaugcaauca      480

cuacuaccag accuaccacu agaagcaugg ccagcaacag acaaaaccaa aagagaagaa      540

guagacuaag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  1968
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt6)

<400>  1968
gggagaaagc uuaccauggg aacauggaua uucuucgccu gccuacuagg cgcaucacua       60

gcaaugccac uaccaccaca cccaggacac ccaggauaua uaaacuucuc auacgaagua      120

cuaacaccuc uaaaauggua ccaaaacaug auaagacauc cauacacauc auacggauac      180

gaaccaaugg gcggaugguu acaccaccaa auaauaccag uagucuccca acaaacacca      240

caaucacacg cauuacaacc ccaccaccac auacccaugg uaccagccca acaaccagga      300

auaccacaac aaccaaugau gccacuacca ggacaacacu caaugacacc aacacaacac      360

caccaaccaa accucccauu accagcacaa caacccuucc aaccacaacc cguacaacca      420

caaccacacc aaccacuaca accacaauca ccaaugcacc caauacaacc acuacuaccc      480

caaccaccac uaccaccaau guucucaaug caaucacuac uacccgaccu accauuagaa      540

gcauggccag caacagacaa aacaaaaaga gaagaaguag acuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  1969
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt6)

<400>  1969
gggagaaagc uuaccauggg aacauggaua cuauucgcau gccuacuagg agcagcauuc       60

ucaaugccac uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua      120

cuaacaccac uaaaauggua ucaaaacaug auaagacacc caucacuauu accagaccua      180

ccacuagaag cauggccagc aacagacaaa acaaaaagag aagaaguaga uuaaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  1970
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt6)

<400>  1970
gggagaaagc uuaccauggg aacauggaua cuauucgcau gccuacuagg agccgcauuc       60

ucaaugcccc uaccaccaca cccaggacac ccaggcuaca uaaacuucuc auacgaagac      120

cuauaccuag aagcaauaag aauagacaga acagcauucg uccuaacacc auuaaaaugg      180

uaccaaaaca ugauaagaca cccauacaca ucauacggau acgaaccaau gggaggcugg      240

cuacaccacc aaauaauacc cguaguaucc caacaaacac cacaaucaca cgcacuccaa      300

ccacaccauc acauaccuau gguaccagca caacaacccg gaauaccaca acaaccaaug      360

augccacuac caggacaaca cucaaugaca ccuacacaac accaccaacc aaaccuacca      420

uuaccagcac aacaaccauu ccaaccacaa ccaguacaac cacaaccaca ccaaccccua      480

caaccacaau caccaaugca cccaauacaa ccacuacucc cacaaccacc ccuaccaccc      540

auguucucaa ugcaaucuuu acuaccagau uuaccauuag aagcauggcc agcaacagac      600

aaaacaaaaa gagaagaagu agauuaagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  1971
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt6)

<400>  1971
gggagaaagc uuaccauggg cacauggaua cuauucgcau gccuacuagg agcagcauuc       60

uccaugccac uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua      120

cucaccccac uaaaauggua ccaaaacaug auaagacacc caacaccaca aucccacgca      180

cuccaaccac accaccacau accaauggua ccagcacaac aaccaggaau accacaacaa      240

ccaaugaugc cacuaccagg acaacacuca augacaccaa cacaacacca ccaacccaac      300

cuaccacuac cagcacaaca accauuucaa ccacaaccag uacaaccaca accacaccaa      360

ccacuacaac cacaaucacc aaugcaccca auacaaccac uacucccaca accaccacua      420

cccccaaugu ucucaaugca aucacuauua ccagaccuac cacuagaagc auggccagca      480

acagacaaaa caaaacgaga agaaguagac uaaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  1972
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt6)

<400>  1972
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuu       60

ucauacgaag uacuaacccc acuaaaaugg uaccaaaaca ugauaagaca ccccuacaca      120

ucauacggcu acgaaccaau gggaggaugg cuacaccacc aaauaauacc aguaguauca      180

caacaaacac cacaaucaca cgcacuccaa ccacaccacc acauaccaau gguaccagca      240

caacaacccg gaauaccaca acaaccaaug augccacucc caggacaaca cucaaugaca      300

ccaacacaac accaccaacc aaaccuacca cuaccagccc aacaaccauu ccaaccacaa      360

ccaguacaac cacaaccaca ccaaccacua caaccacaau caccaaugca cccaauacaa      420

ccacuacuac cacaaccccc acuaccccca auguucucaa ugcaaucacu acuaccagac      480

cuaccacuag aagcauggcc agcaaccgac aaaacaaaaa gagaagaagu cgacuaagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  1973
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt6)

<400>  1973
gggagaaagc uuaccaugcc agggguagcu agacuaccuc uacucuuagg acuccuauug       60

uuaccacggc caggaagacc guuagaucua gcggacuaca cauaugaucu cgcagaagaa      120

gacgacagug aaccgcuaaa uuacaaagau ccauguaaag cggccgcauu uuugggagau      180

auagcauuag augaagaaga cuuaagagca uuucaaguac aacaagcugu ugaucuaaga      240

agacacacgg cccgaaaaag caguauaaaa gcagcgguac caggcaacac aagcacgcca      300

ucaugccaaa guacaaacgg acaaccacaa agaggggcuu gcgggagaug gagaggaaga      360

agcagaagca gacgcgcagc uacuucaaga ccugaaagag uuuggccuga cggcguaaua      420

ccauucguaa uaggaggcaa uuuuacagga agucagcgcg caguuuuucg gcaagcaaug      480

cgccacuggg aaaaacauac uuguguaaca uucuuagagc gaacagauga agauuccuau      540

auaguuuuca cauacaggcc cugcggaugu uguucauaug uaggaagacg cgggggagga      600

ccacaagcga uaaguauagg aaaaaauugu gacaaauucg gaauaguugu ccaugaauua      660

ggucacguug ugggauucug gcacgaacac acacgaccag auagagacag acauguaagu      720

auaguaaggg aaaauauaca accagggcag gaauacaacu uuuuaaaaau ggaaccccaa      780

gagguagaau cacuuggcga aacuuacgau uucgauagua uaaugcauua ugcuagaaau      840

acauuuucga gaggaauauu ccuagacacu auaguaccga aauacgaagu aaauggagug      900

aaacccccaa uaggccaaag aacuagacua ucaaaaggag acauagcaca ggcaagaaaa      960

uuauauaaau gucccgcgug uggugaaaca uuacaagauu cuacaggaaa uuuuucaucu     1020

ccugaauauc cuaauggcua uagugcacac augcauugug uauggcgcau uucaguaaca     1080

ccaggagaaa aaauuauuuu gaauuucaca agucuagacu uauacagaag uagauuaugu     1140

ugguaugacu auguagaagu cagggaugga uucuggagaa aagcuccucu aaggggaaga     1200

uuuuguggaa gcaaauuacc ugaaccaaua guuagcacag auucaagacu uuggguagaa     1260

uuuagaagua guucaaauug gguaggaaaa ggauuuuucg caguguauga agcaauuugc     1320

gguggagaug uaaaaaaaga cuaugggcac auacaaagcc caaacuaucc ugaugauuau     1380

agaccaucaa aaguauguau auggcgaaua caaguuagug aaggguuuca cguaggauua     1440

acuuuucaau ccuucgaaau agaaagacau gacucuugcg cauaugauua uuuagaaguu     1500

agagacggac auagugagag uaguacucua aucggaagau acugcggcua ugaaaaaccu     1560

gaugacauua aaagcacuag cucuagauua uggcuaaaau uuguaaguga ugguagcaua     1620

aauaaggcag guuuugcagu aaacuuuuuu aaagagguug augaauguuc gaggccuaau     1680

agaggugguu gugaacaacg gugcuugaau acacuaggaa gcuacaaaug cucaugcgau     1740

ccaggcuacg aauuagcgcc agauaaaaga agaugugaag cagcaugugg aggauuuuug     1800

acuaaacuaa auggaucaau aacaagucca gguuggccga aagaauaccc uccuaauaaa     1860

aacuguauuu ggcaacuugu agcaccuacu caauauagaa uaucauugca auucgauuuu     1920

uucgagacag aaggaaacga cguauguaaa uaugacuuug uggaaguaag aaguggucua     1980

accgcugaua guaagcuaca cggaaaauuc ugcgguagug agaaaccaga aguaauaacg     2040

ucacaauaca auaauaugag aguugaauuu aagagugaca auacaguuuc aaaaaaagga     2100

uuuaaagcac auuuuuucuc agacaaagau gaguguagua aagauaaugg aggaugccag     2160

caagacugcg uaaauacauu cggaagcuau gaaugucaau gucgauccgg cuuuguauua     2220

cacgauaaua aacacgauug uaaagaagcu ggaugcgauc acaaaguaac gaguacuagc     2280

ggaacaauua caagcccaaa uuggccggac aaauaucccu caaaaaaaga auguacuugg     2340

gcaauaucuu cuacaccggg ucauagagug aaauuaacau ucauggaaau ggacauagaa     2400

ucacaaccag aaugugcaua ugaucaccuu gaaguauucg augguagaga ugcuaaagcu     2460

ccaguacugg gucgcuuuug uggaaguaaa aaacccgagc cuguauuagc aacaggauca     2520

agaauguucc uuagauucua cuccgacaau ucaguacaga gaaaagguuu ccaagcuucu     2580

cacgcaacag aauguggagg ccaagugcga gcggauguaa aaacaaaaga cuuauauucu     2640

cacgcacagu uuggagacaa uaauuaucca ggaggugugg auugugaaug gguuauaguc     2700

gcagaagaag gauacggagu agagcuaguc uuucaaacau uugagguaga agaagaaacu     2760

gauuguggau acgacuauau ggaacucuuu gauggauacg acucaacagc accccgauua     2820

gguagauauu guggaucugg accacccgaa gaaguauauu ccgcaggaga cagcguauua     2880

gucaaguucc acuccgauga uaccaucacu aaaaaaggau uucaucuuag auauacaagc     2940

acaaaauuuc aagacacucu ucacagccga aaauagggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  1974
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt6)

<400>  1974
gggagaaagc uuaccauggu agcugguacu agaugccuac uagcauuacu cuuaccacaa       60

guauuacuag gaggagcagc aggauuaguc ccagaacuag guagaagaaa auucgcagcu      120

gccucaucag gaagacccag cucacaaccu ucagacgaag uccuaucaga auuugaauug      180

agauuacuau caauguucgg acuuaaacaa agaccaacac caucaagaga ugcaguagua      240

ccaccauaua ugcuagauuu auauagaaga cacucaggac aaccaggaag uccagcucca      300

gaccauagau uagaaagagc agcaaguaga gcaaacacag ucaggagcuu ucaucacgaa      360

gaaucacuag aagaauuacc agaaacauca ggaaaaacca caagaagauu uuucuuuaac      420

cuuaguucaa uaccaacaga agaauucauc acaagugcag aacuacaagu cuucagggaa      480

caaaugcagg acgcacuagg aaauaauuca ucauuccauc auagaauaaa uaucuaugaa      540

auaauaaaac cagcaacagc caacucaaaa uucccaguaa caagacuacu agacacaaga      600

cuaguaaacc aaaacgcaag cagaugggaa agcuuugaug uaacaccagc aguaaugcga      660

uggacagcac aaggucacgc aaaucacgga uucguagucg aagucgcgca ucuagaagaa      720

aaacaaggug uaagcaaacg acauguaaga auaaguagaa guuuacacca agaugaacau      780

ucauggucac aaauaagacc acuccuagua acauucggac augacgguaa aggacaccca      840

cuacacaaac gagaaaaaag acaagcaaaa cauaaacaaa gaaaaagacu aaaaucauca      900

ugcaaaagac auccguuaua uguugacuuu ucagauguag gauggaacga cuggaucgua      960

gcacccccag gauaucacgc auucuauugu cauggagaau guccauuucc auuagcagau     1020

cacuuaaaua gcacaaacca cgccauugua caaacucuag ucaauucagu caauucaaaa     1080

aucccaaaag caugcugcgu accuacagaa cuaucagcaa uuucaaugcu auaccuagac     1140

gaaaaugaaa aaguaguacu uaaaaacuau caagacaugg uuguagaagg auguggaugc     1200

agauaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  1975
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt6)

<400>  1975
gggagaaagc uuaccaugau acccggaaac agaaugcuaa ugguaguauu acuaugccaa       60

guauuacuag gaggagcuag ccaugccagc uuaauuccug aaacaggcaa aaagaaagua      120

gcagaaauac aaggacacgc aggaggaaga agaucaggac aaagccauga acuacuaaga      180

gacuucgaag caacauuacu acaaauguuu ggacuacgac gaagaccaca accuaguaaa      240

agcgcaguca uaccagacua uaugagagau cuauaucgcu uacaaagcgg agaagaagaa      300

gaagaacaaa uacauucaac aggauuagaa uacccagaaa gacccgcauc aagagcaaau      360

acagugaggu cauuccauca ugaagaacau cuagaaaaua uaccaggaac aucagaaaau      420

ucagcauuca gauuuuuauu caauuuaagu ucuauaccag aaaacgaagu aauaucaucu      480

gcagaacuaa gauuauucag agaacaaguu gaucaaggac cagacuggga aagagguuuu      540

cacagaauaa auaucuauga aguaaugaaa ccuccagcag aaguaguucc agggcaucua      600

aucacaagau uacucgauac aagauuagua caccauaacg uaacacgaug ggaaacauuu      660

gauguaucac cagcaguucu aagauggaca agagaaaaac aaccgaauua cggauuagca      720

auagaaguua cucacuuaca ucaaacaaga acccaccaag gacaacaugu aagaauaucc      780

cgaucauuac cacaaggcuc aggaaauugg gcacaacuaa gaccacuccu cguaacauuu      840

ggacaugacg gaagaggaca ugcucucacc agaagaagac gagcaaaaag aucaccaaaa      900

caccauagcc aaagagcuag aaagaaaaau aaaaauugca gaagacauag uuuauacguu      960

gacuucucag auguaggaug gaaugauugg auaguagcac caccugguua ccaagcauuu     1020

uauugucacg gagacugucc auuuccuuua gcagaucacu uaaacaguac aaaucacgca     1080

auaguacaaa cucuaguuaa cucaguaaac agcucuauac caaaagcaug cuguguccca     1140

acagaacuau cggcaauuuc aauguuauau uuagaugaau augauaaagu aguacuuaaa     1200

aauuaucaag aaaugguagu agaaggaugc ggauguagau aaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  1976
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt6)

<400>  1976
gggagaaagc uuaccaugcc aggauuaggu cguagagcac aaugguuaug cugguggugg       60

gguuuacuau guucauguug uggcccacca ccccuaagac caccauuacc cgcagcagcg      120

gcugcagccg caggaggaca acuauuagga gauggaggaa guccaggcag aacagaacaa      180

ccaccgccaa gcccccaaag cucaucugga uuucuauaca gaagauuaaa aacacaagaa      240

aagagagaaa ugcaaaaaga aauacuaucg guauuaggac ugccacaucg acccagacca      300

cuacacggau uacaacaacc ccaaccaccc gcacuucgac aacaagaaga acaacaacaa      360

caacaacaac uaccaagagg cgaaccucca ccaggaagau uaaaaucagc accacuauuu      420

auguuagauu uauauaacgc auuaucagca gacaaugacg aagacggagc aucagaagga      480

gaaagacaac aaucauggcc ccaugaagca gcaucaaguu cacaacgaag acaaccaccu      540

ccaggagcug cucauccauu aaacagaaaa ucacuucucg ccccaggaag uggcucugga      600

ggugcaaguc cauuaacauc agcacaagau agcgcuuucu uaaaugaugc agauauggua      660

augucauuug uaaaucuagu cgaauacgau aaagaauuuu caccaagaca acgacaucau      720

aaagaauuua aauucaauuu aagucaaaua ccugaaggug aaguaguuac agcugcugaa      780

uuucgaauau auaaagacug uguaauggga ucauuuaaaa accaaacauu cuuaauauca      840

auauaucaag uuuuacaaga acaucaacau agagauagug aucucuuuuu acuagauaca      900

agaguaguau gggcuaguga agaagguugg uuagaauuug acauaacagc uacgaguaau      960

uuauggguug uaacaccaca acauaauaug ggucuacaac uuagcguagu uacacgagau     1020

gguguacaug uacacccaag agcagcaggu cuaguaggaa gggauggacc uuaugacaag     1080

caaccauuca ugguagcauu cuuuaaagua agcgaaguuc auguaagaac uacaagauca     1140

gcuucaucaa gaagaagaca acaaagucga aacagaagua cacaaaguca agauguugca     1200

agaguaucca gugcaucuga uuauaacagu agcgaacuaa aaaccgcaug uagaaaacac     1260

gaauuauacg ucagcuuuca agaucuagga uggcaagauu ggauaaucgc accaaaagga     1320

uaugcagcca auuauuguga uggagaaugc aguuuuccuu uaaaugcaca caugaaugca     1380

acaaaucacg cuauaguuca aacacuuguu cacuuaauga auccugaaua cguaccaaaa     1440

ccauguugcg caccuacaaa auuaaacgca auaucaguac uauacuuuga ugauaauuca     1500

aacguaauac uuaaaaagua uagaaauaug guaguaagag caugugguug ucacuaagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  1977
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt6)

<400>  1977
gggagaaagc uuaccaugca uguaagauca cuccgagcag cagcaccaca cucauuugua       60

gcauuauggg caccacuauu cuuauuaaga uccgcacucg cagacuucag uuuagacaau      120

gaaguacacu caucauuuau acaucgaaga uuacgauccc aagaaaggag agaaaugcaa      180

agagaaauac ucucaauacu agguuuaccc cacagaccaa gaccacaccu acaaggaaaa      240

cauaauuccg caccaauguu caugcuagau cuauacaacg caauggcagu agaagaagga      300

ggaggaccag gaggccaagg uuucucauac ccauauaaag caguauucag uacacaagga      360

ccuccacuag caucccuaca agauucucac uucuuaacug augcagauau ggucauguca      420

uucguuaacu uaguagaaca ugauaaagaa uuuuuucacc caagauauca ccaucgugaa      480

uuuagauucg accuaucaaa aauuccagaa ggagaagccg uaacagcagc agaauucagg      540

auuuauaaag acuauauccg agaacgauuc gacaacgaaa cauucagaau aucaguauau      600

caagucuuac aagaacaucu cggccgagaa ucagacuuau ucuuauuaga uucgagaacu      660

cuaugggcau cugaagaagg augguuagua uuugauauaa cagcaacaag caaucauugg      720

guaguaaacc cccgacauaa ucuaggauua caauuaucag uagaaacacu ugauggccaa      780

agcauuaacc caaaauuagc aggacuaaua ggcagacaug guccacaaaa caaacaacca      840

uucaugguag cauuuuucaa agcaacagaa guccauuuca gaaguauaag aucaacagga      900

aguaaacaaa gaucacaaaa cagaucaaaa acaccaaaaa aucaagaagc acuaagaaug      960

gcuaacguag cagaaaauag cucuagugac caaaggcaag ccuguaaaaa acacgaauua     1020

uauguaucau ucagagauuu aggauggcaa gauuggauca uagcaccaga aggauaugca     1080

gcauauuacu gugaaggaga augugcuuuc ccauuaaacu cauacaugaa cgcaacaaau     1140

cacgcaaucg uacaaacacu cguacacuuu auuaauccag aaacaguacc aaaacccugc     1200

ugcgcaccca cacaauuaaa cgcaauauca guacuauacu uugacgauuc aucaaacgua     1260

auauuaaaaa aauacagaaa cauggucgua agagcaugug guugccauua aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  1978
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt6)

<400>  1978
gggagaaagc uuaccaugaa agcaucagca gcacuacuau gccuacuacu aacagcagca       60

gcauucucac cacaaggacu agcacaacca guaggaauaa acacaucaac aacaugcugc      120

uacagauuca uaaacaaaaa aauaccaaaa caaagacuag aaucauacag aagaacaaca      180

ucaucacacu gcccaagaga agcaguaaua uucaaaacaa aacuagacaa agaaauaugc      240

gcagacccaa cacaaaaaug gguacaagac uucaugaaac accuagacaa aaaaacacaa      300

acaccaaaac uauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  1979
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt6)

<400>  1979
gggagaaagc uuaccauguu acuaacuuug auaauauuau uaccaguugu uucaaaauuu       60

ucuuuugugu cauuaucugc accgcaacac uggaguuguc cagaaggaac ucuagcugga      120

aauggaaauu cuacaugugu ugggccugca ccauuucuaa uauucagcca uggaaacuca      180

auuuucagaa uagauacuga gggaaccaac uaugagcaac ucguugucga cgcuggagua      240

ucuguaauaa uggauuuuca uuacaaugag aaacgcauau acuggguuga cuuagaacga      300

caauuauuac aaagaguauu ucuaaaugga agcagacaag aaaggguaug caauauagag      360

aaaaauguga guggaauggc aaucaauugg auaaaugaag aagugauaug gucaaaccaa      420

caagaaggaa uuauaacagu aacagauaug aaaggcaaua auagccauau acuguugagc      480

gcccuuaaau auccagcuaa cguagcagua gauccaguag aaagauuuau auuuuggagu      540

ucugaagucg caggaucacu auaccgagcu gaccuugaug gaguaggugu aaaggcuuua      600

cuagaaacau cagagaaaau cacagcagua agucuugacg uacuagauaa aagauuauuc      660

uggauccaau auaaccgcga agggucuaau ucccuuauau guucauguga cuacgacgga      720

ggcucaguac auauaucaaa acauccgacc caacauaauc uauuugcuau gagccuuuuc      780

ggggacagaa ucuuuuauuc gacauggaaa augaaaacaa uuuggauagc aaauaaacac      840

acaggaaaag acaugguaag aauuaauuua cauagcucuu ucguaccuuu gggagaauua      900

aaaguaguac auccguuggc acagccuaaa gcagaagacg auacauggga accugaacaa      960

aaauugugca aauugcgaaa aggaaacugu ucaucgaccg uuuguggaca agacuuacaa     1020

agucacuugu gcaugugugc ggaaggauau gcucuaucca gagauagaaa auauugugaa     1080

gaugucaacg aaugugcuuu uuggaaucau ggaugcacac uaggaugcaa aaacacacca     1140

gguucuuauu acuguaccug uccaguaggu uuuguuuuac uaccagacgg uaaaagaugu     1200

caccagcuag uaucgugucc acgcaacgua ucugaauguu cucacgauug uguacuuacc     1260

agcgaaggac cauuauguuu uuguccggag ggaaguguac uagaacguga cgguaaaaca     1320

uguucaggau gcucaucacc ugauaacggu gguuguaguc aauuaugcgu cccacuuagu     1380

ccuguaaguu gggaauguga cugcuuccca ggauaugauu ugcaauuaga ugagaaaagc     1440

ugugcagcca gcggaccuca acccuuucuc cuuuucgcaa acagccaaga uauaagacau     1500

augcauuuug auggaacuga uuauggaacg cuauuaaguc aacaaauggg aaugguuuac     1560

gcacuagauc augauccugu agaaaauaaa auauauuuug cucacacagc cuuaaaaugg     1620

auagaacggg caaauaugga cgguagccaa agagaacgac uaaucgaaga aggaguagau     1680

guuccugaag gauuagcagu agauuggauc ggaagacgau uuuauuggac ggauagggga     1740

aaaagccuaa uugguagauc cgaccuuaau ggaaaaagau caaaaauaau aacaaaagaa     1800

aacauaagcc aaccacgcgg aauugcggua cauccaaugg caaaacggcu auuuuggaca     1860

gauacaggaa uaaacccaag aauagaaagu ucuucuuuac agggacuagg acgucuagua     1920

auagcaagcu ccgauuuaau uuggcccagu gguauaacga uagacuuuuu aacugauaaa     1980

cuauacuggu gugaugcaaa gcaaucaguc auugaaaugg caaaucuaga uggaucuaaa     2040

agaagaagac uaacucaaaa cgauguagga cacccauuug ccguagcagu auuugaagau     2100

uauguuuggu ucucagauug ggcaaugcca agcguaauga gaguaaauaa aagaacagga     2160

aaagauagag ucagauugca aggaagcaug uuaaaaccgu ccagucuugu cgucguucau     2220

ccccuugcaa aaccaggugc ggauccaugu cuauaucaaa acggaggaug ugaacauauu     2280

ugcaagaaac gguuagguac ugcauggugc agcugucgag aaggauucau gaaagcgagc     2340

gaugguaaaa cauguuuagc acucgaugga caucaacuac uagcuggcgg agaaguagac     2400

cugaaaaacc aagugacacc ccuugauaua cuuaguaaaa ccagaguaag ugaagauaau     2460

auaacggaau cacaacauau guuaguagca gaaaucaugg ugagcgauca agaugauugu     2520

gcacccguag gauguaguau guaugcaaga ugcaucucag aaggagaaga cgcaaccugc     2580

cagugcuuaa aaggcuuugc cggcgacggc aaacugugcu cagauauuga ugagugcgaa     2640

augggugugc ccguuugucc uccagcguca uccaaaugua uaaauacaga aggagguuau     2700

guauguagau gcagcgaggg uuaucaaggu gauggcauac acuguuugga uaucgaugaa     2760

ugucaauuag gagaacauuc uuguggggaa aaugcaaguu guacaaauac agaaggaggu     2820

uauacuugua ugugugcugg ccguuuaagu gaaccuggcu uaauaugucc agacagcacu     2880

ccgccuccuc accuaagaga ggaugaucac cauuacagcg uacgcaauag cgauucagaa     2940

ugcccucuaa gucacgacgg guacugucua caugacggag uauguaugua cauagaggcu     3000

uuagauaagu augcauguaa cugugucguu gguuacauag gagaaagaug ucaauaucga     3060

gauuuaaaau ggugggaauu aagacacgcg ggacauggcc aacaacaaaa aguaauaguc     3120

guagccgucu gcguaguugu ucuaguaaug uuacuacuac ugagucuuug gggugcacac     3180

uauuauagaa cacaaaaacu acuaucgaaa aaucccaaaa auccauauga agaaagcagu     3240

agagauguaa ggucaagacg accggcugac acagaagaug ggaugucaag uugcccacaa     3300

ccaugguuug uaguaauaaa agagcaucaa gaccuuaaaa acggagguca gccaguagcu     3360

ggagaagacg gucaggcugc ggaugggagu augcaaccaa caucuuggag acaagaaccu     3420

caacugugcg gaauggguac ggagcaaggc ugcuggaucc cugucagcuc agacaaaggc     3480

agcuguccuc aagugaugga acgaucauuc cauaugccgu cauacgggac acaaacguug     3540

gaaggaggag uggaaaaacc acauagucua uuauccgcaa acccauuaug gcaacaacga     3600

gcauuagauc caccucauca aauggaauua acucaauaag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  1980
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt6)

<400>  1980
gggagaaagc uuaccaugac agcagguaga agaauggaaa uguuaugcgc aggaagagua       60

cccgcacuac uacuaugccu aggauuccac cuauuacaag caguacuauc aacaacagua      120

auaccaagcu gcauaccagg agaaucauca gacaacugca cagcacuagu acaaacagaa      180

gacaauccaa gaguagcaca aguaucaaua accaaaugcu caucagacau gaacggauac      240

ugcuuacacg gacaaugcau auaccuagua gacaugucac aaaacuacug cagaugcgaa      300

gucggauaca caggaguaag augugaacac uuuuuucuaa caguacauca accacuauca      360

aaagaauacg uagcacuaac aguaauauua auaauacuau uucuaauaac aguagucgga      420

ucaacauacu acuucugcag augguacaga aacagaaaau caaaagaacc aaaaaaagaa      480

uacgaaagag uaacaucagg agacccagaa cuaccacaag uauaaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  1981
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt6)

<400>  1981
gggagaaagc uuaccauggc agaaggagaa auaacaacau ucacagcacu aacagaaaaa       60

uucaaccuac caccaggaaa cuacaaaaaa ccaaaacuac uauacugcuc aaacggagga      120

cacuuccuaa gaauacuacc agacggaaca guagacggaa caagagacag aagcgaccaa      180

cacauacaac uacaacuauc agcagaauca guaggagaag uauacauaaa aucaacagaa      240

acaggacaau accuagcaau ggacacagac ggacuacuau acggaucaca aacaccaaac      300

gaagaaugcc uauucuuaga aagacuagaa gaaaaccacu acaacacaua cauaucaaaa      360

aaacaugcag aaaaaaacug guucguagga cuaaaaaaaa acggaucaug uaaaagagga      420

ccaagaacac acuacggaca aaaagcaaua cuauuccuac cauuaccagu cucaagcgac      480

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  1982
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt6)

<400>  1982
gggagaaagc uuaccauggu ugggguagga ggaggagacg uagaagaugu aacaccaagg       60

ccaggaggau gucaaauaag cggaagagga gcaagaggau guaaugggau accaggagcg      120

gcagcauggg aagcugcauu accaagaaga agaccuagga gacauccaag uguuaaucca      180

agaucuagag cagcggggag uccaagaaca agaggaagaa gaacagaaga aagaccaagu      240

gggucaagau uaggagauag agguaggggg agagcauuac cagguggaag auuaggaggu      300

agaggaagag gaagagcacc agaaagagug ggaggaagag gaaggggaag aggaacagca      360

gcaccaagag cagcaccagc ugcaagagga aguagaccag ggccggcagg aacaauggca      420

gcaggaagua uaacaacauu accagcauua ccagaagacg gaggaucagg agcauuucca      480

ccaggacauu uuaaagaccc aaaaagauua uauuguaaaa acggaggauu uuuucuaaga      540

auacauccag auggaagagu cgauggugug agggaaaaaa gugauccgca uauaaaauua      600

caauuacaag cagaagaacg aggaguugua aguauaaaag gaguaugugc aaauagauau      660

cuagcaauga aagaagaugg aagauuauua gcaaguaaau guguaacaga cgaauguuuu      720

uuuuuugaaa gauuagaaag caauaauuau aauacuuaua gaaguagaaa auauacaagc      780

ugguauguag cuuuaaaaag aacaggacaa uauaaacuag gaaguaaaac aggaccagga      840

caaaaagcaa uacuauuucu accaaugagc gcaaagucau aaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  1983
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt6)

<400>  1983
gggagaaagc uuaccaugca caaauggaua cuaacaugga uacuaccaac acuacuauac       60

agaagcugcu uccacauaau augccuagua ggaacaauaa gccuagcaug caacgacaug      120

acaccagaac aaauggcaac aaacguaaac ugcucaucac cagaacgaca cacaagauca      180

uacgacuaca uggaaggagg agacauacga guaagaagac uauucugcag aacacaaugg      240

uaccuaagaa uagacaaaag aggaaaagua aaaggcacuc aagaaaugaa aaacaacuac      300

aacauaaugg aaauaagaac aguagcaguc ggaaucguag caauaaaagg aguagaauca      360

gaauucuauu uagcaaugaa caaagaagga aaacuauacg caaaaaaaga augcaacgaa      420

gacugcaacu ucaaagaauu aauacuagaa aaccacuaca acacauacgc aucagccaaa      480

uggacacaca acggaggaga aauguucgua gcacuaaacc aaaaaggaau accaguaaga      540

ggaaaaaaaa caaaaaaaga acaaaaaaca gcacacuucc uaccaauggc aauaacauaa      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  1984
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt6)

<400>  1984
gggagaaagc uuaccaugaa acuacuacca ucaguaguac uaaaacuauu uuuagcagca       60

guacuaucag cacuaguaac uggagaauca cuagaaagau uaagaagagg acuagcagca      120

ggaaccucaa auccagaccc accaacagua agcacagacc aauuauuacc acuaggagga      180

ggaagagaca gaaaaguaag agaccuacaa gaagcagacc uagaccuauu aagaguaaca      240

cuaucaucaa aaccacaagc acuagcaaca ccaaacaaag aagaacacgg aaaaagaaaa      300

aaaaaaggaa aaggacuagg aaaaaaaaga gacccaugcc uaagaaaaua uaaagacuuc      360

ugcauacacg gagaaugcaa auacgucaaa gaacuaagag caccaagcug cauaugccac      420

cccggauacc auggagaaag augccacgga cuaucacuac caguagaaaa ccgacuauac      480

acauacgauc acacaacaau auuagcagua guagcaguag uauuaucauc aguaugcuua      540

cuaguaauag uaggacuauu aauguucaga uaccacagac gaggaggaua cgauguagaa      600

aaugaagaaa aaguaaaacu aggaaugaca aauucacauu aaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  1985
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt6)

<400>  1985
gggagaaagc uuaccaugug gguaacuaaa cuuuuaccag cguuauuacu ccaacacgua       60

uuacuacacc uccuauuauu accaauagcu auaccauaug cagaaggaca aagaaaacgc      120

agaaacacca uacaugaauu uaaaaaaucg gccaaaacaa cucuaaucaa aauagaucca      180

gcauuaaaaa uaaaaacaaa aaaaguuaac acagccgauc aaugugcaaa ccgcugcaca      240

cguaauaaag gccuaccauu cacaugcaaa gcauuuguau uugauaaagc acguaagcaa      300

ugucuauggu uuccauuuaa uagcaugagc ucuggcguaa aaaaagaauu uggacaugaa      360

uuugaccuau acgaaaauaa agacuauauu agaaacugua uuauaggaaa aggaagauca      420

uauaagggca caguauccau aacaaaauca ggaauuaaau gucaaccaug gucauccaug      480

auaccccacg aacauucauu uuuaccauca aguuauagag gaaaagauuu acaagaaaac      540

uauugccgaa acccaagagg agaagaaggc ggaccuuggu guuuuacauc aaacccagaa      600

gucagauaug aaguuuguga uauaccccaa uguucagaag uagaauguau gacauguaau      660

ggagaaucau auagaggucu aauggaucac acagaaagug guaagauaug ccaaagaugg      720

gaucaucaga caccacaccg acauaaauuu uuacccgaaa gauacccuga uaaaggauuu      780

gaugauaauu acugucgaaa cccugauggg cagccaagac caugguguua uacuuuagac      840

ccccacacaa gaugggaaua uugcgcuaua aaaacaugcg cggauaauac aaugaaugau      900

acagauguac ccuuagaaac uacugaaugu auacaaggac aaggugaggg uuaucgcggc      960

acugucaaua cuauauggaa uggcaucccc ugucaaagau gggauucaca auauccccau     1020

gaacaugaua ugacaccaga aaacuuuaaa uguaaagauu uacgagaaaa uuauugccgu     1080

aauccagaug guucagaauc ucccuggugc uuuacaaccg auccaaauau cagagucggg     1140

uacuguucac agauaccaaa uugcgacaug ucucaugguc aagauuguua uaggggaaac     1200

ggaaaaaauu auaugggaaa cuuaucucaa acuagaucag guuuaacuug uaguaugugg     1260

gauaaaaaua uggaagauuu acacagacau auauucuggg aaccugaugc aagcaaacua     1320

aacgaaaacu acuguaggaa uccagacgau gaugcacaug gcccuuggug cuauacagga     1380

aauccauuaa ucccguggga uuauuguccc auaucgcgau gugaaggcga cacaacgcca     1440

acuauaguaa accuagauca uccagugaua ucaugugcaa aaacuaaaca auuaagaguc     1500

guaaauggaa uaccaacaag aacaaacauu ggauggaugg uaucacuccg auacagaaau     1560

aaacauauau guggaggauc auuaauaaaa gaaagcuggg uuuuaaccgc aagacaaugu     1620

uuuccaucuc gagaccuuaa agacuaugaa gcaugguuag gaauacacga cguacauggu     1680

agaggagacg aaaaauguaa acaaguacua aauguuuccc aacuuguaua ugguccagaa     1740

gguucagauu uaguauuaau gaaauuagcg agacccgcag uuuuagauga uuucguaagc     1800

accauagacc uaccgaauua uggauguacu auaccagaaa aaacaaguug uaguguauac     1860

ggauggggau auacaggccu aauaaauuau gacggauuac uaagagucgc acacuuauau     1920

auaaugggaa acgaaaaaug uucacaacau cacagaggua aaguaacauu aaaugaaagu     1980

gaaauaugug caggagcuga aaaaauaggc ucaggaccgu gugaaggaga uuauggaggc     2040

ccacuaguau gugaacagca caaaaugaga augguacuag gaguaauagu accaggccga     2100

ggaugugcaa ucccaaacag accaggaauc uuuguuagag ucgcuuacua ugcuaaaugg     2160

auacauaaaa uaauacuaac auauaaagua ccacaaucau aaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  1986
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt6)

<400>  1986
gggagaaagc uuaccauggc aaaagcagca gcaauuggaa uagauuuggg uacaacauac       60

aguugcgugg gcguguuuca acacggaaaa guagaaauaa uagcaaacga ucaaggaaac      120

aggacaacac caucauacgu ggcauuuaca gacacagaac gauuaauagg ggacgcugcu      180

aaaaaccaag uagcauuaaa cccccaaaac acaguguucg augcgaaaag gcuuauaggu      240

cggaaauuug gggaucccgu aguccaaagc gauaugaaac auuggccauu ccaagucauu      300

aaugauggag auaaaccaaa agugcaagua aguuacaagg gugaaacaaa agcauuuuac      360

ccggaagaaa uaucaaguau gguacuaacu aaaaugaagg aaauagcuga agcauaccua      420

ggauacccag uaacaaaugc gguaauaaca gugccagccu acuuuaacga uucgcaacga      480

caagcaacga aagacgcagg ggucauagcc ggucuaaaug ucuuaagaau aauaaaugaa      540

ccaacagcag cagcgauagc uuacggacua gauagaacag gaaaagguga aagaaacgua      600

cuaauauuug auuugggagg aggaacauuu gacguaucga uauuaaccau agaugacggc      660

auauuugaag uaaaggcaac ggcaggagac acacaucugg gaggagaaga cuuugauaau      720

cggcuaguaa aucacuuugu cgaagaauuu aaaagaaaac acaagaaaga uauaagucaa      780

aacaaaagag caguaagaag acuuagaacc gccugcgaaa gagcaaaaag aacacuaagc      840

ucaucaacac aagcaaguuu ggaaauagau ucauuauuug aagguauaga cuucuauacu      900

ucaauuacaa gagccagauu cgaagaacua uguagugauu uauuuagaag uacguuagaa      960

ccgguagaaa aagcguuaag agaugcuaaa cuagauaaag cucaaaucca ugaucuagua     1020

uuaguaggag gaaguacaag aauaccaaaa gugcaaaaau uacuucaaga uuucuuuaac     1080

ggaagagauc uaaauaaauc gauaaaucca gaugaagcgg uagcguacgg agcagcagua     1140

caagcagcaa uauugauggg agauaaaagu gaaaacguuc aagauuuauu auuacuagau     1200

guagccccau uaaguuuagg acucgagaca gcugguggag uuaugacagc gcuaauaaaa     1260

aggaacucaa caauaccaac aaaacaaaca caaauauuua caacauauag ugauaaucaa     1320

ccaggaguac uaauacaagu auaugaagga gaaagagcga ugacaaaaga caauaauuua     1380

cuuggaagau ucgaacuuag uggaauacca ccagcaccac gaggaguacc acaaauagaa     1440

guaacguuug auauugacgc aaacggaaua cuaaauguaa ccgcuacaga uaaaagcaca     1500

ggaaaagcaa acaaaauaac uauaacaaau gauaaaggua gauuaaguaa agaagaaaua     1560

gaacguaugg uacaagaagc agaaaaauac aaagcagaag acgaaguaca aagagaaagg     1620

gucagcgcga aaaaugcacu agaaaguuac gcauucaaua ugaaaagugc aguagaagau     1680

gaaggacuca aaggaaaaau aagugaagca gauaaaaaga aagucuuaga uaaaugucaa     1740

gaagugauaa gcuggcuaga ugcaaauaca uuagcugaaa aagacgaauu ugaacauaaa     1800

agaaaagaac uagagcaagu augcaaccca auaauaagug gcuuguacca aggggcagga     1860

ggaccggggc caggaggcuu uggagcucaa ggaccuaaag gaggaagcgg uagcggacca     1920

acaauagaag aaguagacua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1987
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt6)

<400>  1987
gggagaaagc uuaccauggc aaaagcagca gcgauaggaa uagauuuagg gacaacuuau       60

aguuguguag gaguauucca acauggaaaa guagaaauaa uagcuaauga ccaaggaaau      120

agaacaacuc cuaguuaugu agcauuuaca gacacagaaa gacuaauagg agacgccgcu      180

aaaaaucaag uagcccucaa uccacagaau acaguauucg acgcaaaaag acuuauaggu      240

aggaaauucg gagauccagu gguacaaagc gauaugaaac auuggccauu ucaaguaaua      300

aaugacggag auaaaccaaa aguacaagua ucauacaaag gagaaacaaa agcauuuuau      360

ccugaagaaa ucucaaguau gguacuaaca aagaugaagg aaauugcaga agcauaucuu      420

ggauacccag uaacgaacgc aguaauaaca guaccugccu acuuuaacga cagccaacgu      480

caagcaacua aagacgcagg aguaauagcu ggucuaaacg uacuuagaau uaucaaugaa      540

ccaacugcag ccgcaaucgc auacggacua gaccgaacgg gaaaaggaga aaggaaugua      600

uuaauuuucg accuaggagg aggaacauuc gaugucucua uauuaacuau agacgaugga      660

auuuuugaag uaaaagcaac ggcaggagac acgcauuuag gaggagaaga uuucgauaac      720

cgucuaguaa aucauuucgu ugaagaauuu aaaagaaaac auaaaaagga cauuucgcaa      780

aauaaaagag cagugagaag auuaagaacc gccugugaaa gagcaaaaag aacauuaagc      840

agcaguacgc aagcaagccu ugaaauagau ucacuauuug aaggaauaga uuucuacaca      900

ucaauaacaa gagcucgauu ugaagaauua uguagcgacu uguucagauc aacauuagag      960

ccaguagaaa aagcacuaag agacgcaaaa uuagacaaag cacaaauaca ugaccuagua     1020

uuaguuggag gcaguacacg aauaccaaaa guacaaaaac uucuacaaga cuucuuuaau     1080

ggaagagauc uaaauaaauc aauaaaucca gaugaagcag uagccuacgg ugcggcgguu     1140

caagcagcaa uacugauggg ggacaaauca gaaaauguac aagauuuauu auuauuagau     1200

guggcaccac uaucauuagg auuagaaaca gcuggaggug uaaugacagc acuaauuaaa     1260

cgaaacagca ccauaccaac gaaacaaaca caaauauuua ccacguacuc ggacaaucaa     1320

ccgggaguau ugauacaagu auacgaagga gaaagagcaa ugacuaaaga caacaaucua     1380

uuaggaagau ucgaauuauc aggaauaccg ccagcaccaa gaggaguacc acaaauagaa     1440

guaacauucg auauagacgc aaauggcauu uuaaacguaa cagcaacaga caaaucaaca     1500

gguaaagcaa acaaaauaac aauaacaaau gauaaaggaa gacuaucuaa agaagaaaua     1560

gaaagaaugg uacaagaagc cgaaaaauac aaagcagaag augaaguuca aagagaacgu     1620

gugagugcca agaaugcacu ugaaucguau gcguucaaua ugaaaagcgc aguagaagau     1680

gagggccuaa aaggaaaaau aucagaagca gacaaaaaga aagucuugga uaagugucaa     1740

gaaguaauaa guugguuaga ugcaaacaca cucgcagaaa aagaugaauu ugaacauaaa     1800

agaaaagaac uagaacaagu augcaaucca auaauaucag gguuauacca aggagcaggc     1860

ggaccaggac ccgggggauu cggugcccag ggaccaaaag gcgguagugg cagcggacca     1920

accauugaag aaguagauua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1988
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt6)

<400>  1988
gggagaaagc uuaccauggc uacagcaaaa ggaauagcaa uaggaauaga uuuaggaaca       60

acauauucgu guguuggagu auuccaacac ggaaaaguag aaaucauagc aaaugaccaa      120

ggaaacagaa caacaccaag cuauguagca uuuacggaua cagaaagauu aauaggagac      180

gcagccaaaa accaaguagc uaugaaucca caaaauacag uauucgaugc aaaaagacua      240

auaggaagaa aauuuaauga cccaguagua caagcagaua ugaagcuaug gcccuuccaa      300

guuauaaaug aaggagggaa accaaaaguu cuaguaaguu auaaagguga aaauaaagcc      360

uucuauccag aagaaauauc aagcaugguc cuaacaaaac uaaaagaaac cgcagaagca      420

uucuuaggac auccugucac uaacgcagua auaacaguac cagcauacuu caacgauagu      480

caacgucaag caacaaaaga ugcuggaguu auagcaggac uaaauguacu acgaauaauc      540

aacgaaccga cagcagcagc uauagcauau ggacucgaca aaggcggaca aggagaaaga      600

cacgugcuca ucuucgacuu aggcgguggc acauuugaug uauccauacu aaccauugac      660

gauggaauuu ucgaaguaaa agccacagcc ggagacaccc aucuaggggg agaagauuuc      720

gauaaccggu uaguaaguca cuucguagaa gaauuuaaaa gaaaacacaa gaaagauaua      780

agucaaaaua aacgagcagu aagaagauua agaacagcau gugaaagagc caaaagaaca      840

cuuaguaguu caacacaagc aaacuuagaa auagauucau uauacgaagg aauagauuuc      900

uauaccagua uaacaagagc aagauuugaa gaacuaugcg cugauuuauu ucgcggaaca      960

uuagaacccg ucgaaaaagc auuaagagau gcaaaaaugg auaaagcaaa aauacacgac     1020

auaguauuag ugggagguag cacgcgaaua ccaaagguuc aacgauuauu acaagacuau     1080

uuuaauggca gagaccucaa uaaaaguaua aacccugaug aagcaguugc auacggagcu     1140

gcaguacaag cagcuauacu gaugggagac aaaucagaaa aaguacaaga ucuccuacua     1200

cuagacguag cuccacuauc acugggucuu gagacagcgg gaggcguaau gacagcauua     1260

auuaaaagga acucgaccau acccacaaaa caaacacaaa uauuuaccac auauucagau     1320

aaccaaccug gagugcuuau ucaaguauac gaaggagaaa gagcaaugac gaaagauaau     1380

aacuugcuag gaagauuuga ucuaacaggg auuccaccag caccaagagg cgugccacaa     1440

auagaaguca ccuucgacau agacgcaaac ggaauauuaa acgucacagc aaccgauaaa     1500

ucaacaggua aggucaauaa aauuacaaua acaaacgaua aaggaagacu aucaaaagaa     1560

gaaauagaaa gaaugguacu agaugcagaa aaauacaaag cagaagacga aguacaaaga     1620

gagaaaauag cagcuaaaaa cgcgcuagaa aguuacgcau uuaacaugaa aaguguagua     1680

ucugaugaag gauuaaaagg caaaauuuca gaaagcgaua aaaauaaaau acuagacaaa     1740

ugcaaugaac uacuuaguug guuagaagua aaucaacuag ccgaaaagga ugaauuugac     1800

cauaaaagaa aagaacugga acaaaugugu aaucccauca uaacaaaacu auaucaagga     1860

ggcugcacag gaccagcaug uggaaccgga uauguaccag gacguccagc aacaggacca     1920

acaauagaag aaguagacua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  1989
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt6)

<400>  1989
gggagaaagc uuaccauguc agcaagagga ccagcaauug ggauagaucu aggcacaacu       60

uacucaugcg uagguguauu ccaacacgga aaaguagaaa uuauagcaaa cgaucaaggg      120

aacagaacaa caccaaguua uguagcauuu acagacacug aaagauuaau aggugacgca      180

gcuaaaaauc aaguagcaau gaacccuaca aacacaauuu uugacgcaaa acgacuaauc      240

ggaagaaaau ucgaagacgc aacaguacaa ucagauauga aacauuggcc guucagagua      300

guaagcgaag gagggaaacc aaaaguacag guugaauaca aaggagaaac aaaaacuuuc      360

uucccagaag aaauuaguag uaugguccuc acaaaaauga aagaaauagc agaagcauac      420

cuuggaggaa aaguucacuc agcaguaauu acaguaccag cauacuucaa cgauucccaa      480

agacaagcaa cgaaagacgc cgguacaaua acaggauuaa acguguuaag aauuauaaac      540

gaaccuaccg cagcagccau agcguaugga uuagauaaga aaggaugugc aggaggagag      600

aaaaauguau uaauauuuga cuuaggcggu gggacauuug auguaaguau acugacaaua      660

gaagauggga uauuugaagu caaaucgaca gcaggagaca cacauuuagg gggagaagac      720

uuugacaaca gaaugguaag ccaucuagca gaagaguuca aaagaaaaca caagaaagac      780

auaggaccca auaaaagagc ugucaggaga cuuagaacag caugcgaaag agcaaaaaga      840

acauuaucaa guucaacaca agcaaguaua gaaauagauu cgcuauauga aggaguugau      900

uucuauacaa guauaacaag agcaagauuu gaagaacuaa acgccgaucu auuuagagga      960

acauuagaac cgguugaaaa agcacuuaga gacgcaaaau uggauaaagg ccaaauacaa     1020

gaaauuguuc uaguaggagg aaguacacgc auuccaaaaa uacaaaaacu auuacaagac     1080

uuuuucaaug gaaaagaacu caauaaauca auaaacccug augaagcggu agcguauggu     1140

gcagccguac aagccgcaau auuaaucgga gacaaaagug aaaacguaca agaccuacua     1200

uuguuagaug uaacaccauu aucacucgga auugaaacag cuggaggagu aaugacacca     1260

cucauaaaaa gaaauacaac cauucccaca aaacaaacac aaacauucac aacguacagc     1320

gauaaccaaa guagcguccu aguacaagua uaugaaggcg aaagagcaau gaccaaagac     1380

aacaaucuau uaggaaaauu cgacuuaaca ggaauaccuc cagcaccaag gggaguacca     1440

caaauagaag uuacauuuga cauagaugcu aacggaauau uaaacguaac agcagcagau     1500

aaaagcacag gaaaagagaa uaaaauaaca auuacaaacg auaaaggaag acuaagcaaa     1560

gacgauauag auagaauggu acaagaagca gaaagauaua aaagcgaaga cgaagcuaac     1620

agggaucgag ucgcagccaa aaaugcauug gaaagcuaua cauacaauau aaaacaaacu     1680

guagaagaug aaaaauuaag aggaaagaua agugaacaag auaaaaauaa aauuuuagac     1740

aaaugucaag aaguuauaaa cugguuagau agaaaccaaa uggccgaaaa agacgaguac     1800

gaacauaaac aaaaagaacu agaaagaguc uguaauccca uaauuagcaa auuauaccaa     1860

ggaggacccg gagguggaag uggaggagga ggaucaggag caagcggagg cccaacaaua     1920

gaagagguug auuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  1990
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt6)

<400>  1990
gggagaaagc uuaccaugag cgugguaggu auagaucuug gauuccaauc auguuacguu       60

gccguagcaa gagcaggagg aauagaaaca auagccaacg aauacaguga cagauguaca      120

ccggccugca uauccuuugg accuaaaaac agaucaaucg gcgcagccgc aaaaucacaa      180

gugauuucaa augcuaaaaa cacagugcaa gguuucaaaa gauuccacgg acgagcauuu      240

agcgacccau uuguugaagc agaaaaauca aacuuagcuu augauaucgu acaauuaccc      300

acaggacuaa cagguauaaa agucacauau auggaagagg aaagaaacuu cacaaccgaa      360

caaguaaccg cgaugcuauu aucaaaacuc aaagaaacag cagaauccgu cuuaaagaaa      420

ccugucguug acuguguagu aucaguaccc ugcuucuaca cagacgcaga aagaagaucc      480

guaauggaug ccacacaaau agcuggucug aauugcuuac gacuaaugaa ugaaacgacg      540

gcaguugcau uagcuuacgg aauauauaaa caagacuuac ccgcacuaga agaaaaacca      600

agaaacgucg uauuuguaga uaugggucac agugcauauc aaguguccgu augugcuuuu      660

aacagaggua aacuaaaagu auuagcaaca gcuuuugaua cuacuuuagg cggacgaaaa      720

uuugaugaag uucuaguaaa ucauuuuugc gaagaauuug guaagaaaua caaacucgau      780

aucaaaucaa aaauacgugc auuauuacga cuuucacaag aaugugaaaa acuaaagaaa      840

uuaaugagug caaacgcaag cgaccugccu uuaucuauag aauguuucau gaacgaugua      900

gauguaucgg gcacaaugaa cagagguaaa uuccucgaaa ugugcaacga ucuguuagca      960

agaguagaac caccacuacg aaguguauua gaacaaacaa aacuaaagaa agaagacauu     1020

uaugcaguag aaauaguugg aggggcaaca cgaauaccag cgguaaaaga gaaaauuuca     1080

aaauucuuug gcaaagaauu aucaacuaca cuuaaugcag augaagccgu aacuagagga     1140

ugugcacucc aaugugcaau auuaucacca gcuuucaaag uaagagaauu uagcauaaca     1200

gauguaguac cauacccaau uucacugaga uggaacucac cagcagaaga agggucaucc     1260

gacugcgaag uauucaguaa aaaucaugcu gccccuuuuu caaaaguacu aacauucuau     1320

agaaaagaac cuuuuacccu agaagcauac uauucaucac cccaagaucu uccauacccc     1380

gauccagcaa uagcccaauu uagcgugcaa aaaguuacac cucaaaguga uggaucaagc     1440

aguaaaguua aaguaaaagu ccgugugaac guucauggua uauuuagugu aucuucagcc     1500

agccuaguag aaguacacaa aagcgaagaa aaugaagaac caauggaaac ggaucaaaau     1560

gcuaaagaag aagagaaaau gcaaguagac caagaagaac cacauguaga ggaacaacaa     1620

caacaaacac ccgcagaaaa caaagccgaa agugaagaaa uggaaacauc ucaagcagga     1680

ucaaaggaua agaaaaugga ucaaccuccu caagcgaaga aagcaaaagu aaaaacaucu     1740

acagucgauc uuccaauaga aaaccaacuu uuauggcaaa ucgauagaga aauguuaaac     1800

cuauauauag aaaacgaagg aaaaaugaua augcaagaca aauuagaaaa agaaagaaac     1860

gacgcuaaaa acgcaguaga agaauauguu uaugaaauga gagauaaacu gagcggagaa     1920

uacgaaaaau ucguaagcga agacgaucga aauucauuca cccuaaaacu ugaagacacu     1980

gaaaacuggc ucuacgaaga uggagaagac caaccaaaac aaguauacgu agauaaacua     2040

gcagaacuga aaaaccuagg acaaccaaua aaaauaagau uccaagaaag ugaagaacgu     2100

ccuaaauuau ucgaagaacu aggaaaacaa auacaacaau auaugaaaau cauaucaagu     2160

uuuaaaaaca aagaagauca auacgaccac uuagaugccg cagacaugac aaaaguagaa     2220

aaaucuacua acgaagccau ggaauggaug aauaauaaau uaaaccucca gaacaaacaa     2280

ucgcuaacaa uggauccagu ggucaaauca aaagaaauag aagcaaaaau uaaagaacua     2340

acaaguacuu gcucaccaau cauaagcaaa ccaaaaccca aagucgaacc accaaaagaa     2400

gaacagaaaa acgcagaaca aaauggacca guagacggcc aaggugacaa cccaggacca     2460

caagcagcgg aacaagguac ugacacagca guacccucag acagugauaa gaaacuacca     2520

gaaauggaua uagacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  1991
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt6)

<400>  1991
gggagaaagc uuaccauguc aguagucgga auugaccuug gauuuuuaaa cugcuacaua       60

gcaguagcua ggucaggagg aaucgaaaca auagcaaacg aauauagcga uagaugcacc      120

ccugccugca uaucauuagg aucacgcacu agagcaaucg ggaacgcagc caaaucacaa      180

auaguuacaa acguaagaaa uacaauccac ggauucaaaa aacuacacgg cagguccuuu      240

gaugauccaa uaguacaaac ggaaagaaua agacuacccu acgaacugca aaaaaugccc      300

aauggaagug caggcgucaa agucagauau cuagaagaag aaagaccuuu ugcaauagaa      360

caaguaaccg gaauguuauu ggcuaagcua aaagaaacuu cagaaaacgc auuaaagaaa      420

ccuguagcag auuguguuau aucaauacca ucguuuuuca cagaugcaga acgaagauca      480

guaauggcag cagcacaagu agccggccua aacugucuuc gacuaaugaa ugaaacaacu      540

gcaguugccc uagcuuaugg aauuuauaaa caagauuuac cuccucuaga cgaaaaaccc      600

aggaacguag uauucauaga uaugggucau agugcauauc aaguucuagu gugugcauuu      660

aauaaaggaa aauuaaaagu ccuagcaaca acauucgauc cguaucuagg agggcgaaac      720

uucgaugagg cacugguaga cuacuuuugu gacgaauuca aaacgaaaua caagauuaac      780

guaaaagaaa acagcagagc ucuucuaagg cuauaccaag aaugugaaaa acucaaaaaa      840

uuaauguccg cuaaugccuc agaccuacca cuaaauauag aauguuucau gaaugauuua      900

gaugugucaa guaaaaugaa cagagcacaa uuugaacaau uaugcgcauc auuacuagcu      960

cgaguagaac caccauuaaa agccguaaug gaacaagcua auuuacaacg agaagauauc     1020

ucaucaauag aaaucguugg aggagccacc agaauuccag cgguaaaaga acaaauuacu     1080

aaauuuuuuc uuaaagacau cucaacaaca cuaaaugcug acgaagcagu ugcccgggga     1140

ugcgcccucc aaugugcaau acuuagcccu gcauuuaaag uacgagaauu uucaauaaca     1200

gacuuaguuc cauauucgau cacauuaaga uggaaaacau cauucgaaga cggcagcggc     1260

gaaugugaag uauucugcaa aaaccaccca gccccuuuua gcaaaguaau aacauuucau     1320

aaaaaagaac cguuugaauu agaagcauuu uacacaaacu uacacgaagu accauacccu     1380

gaugcacgaa uagguagcuu uacuauacaa aacguauucc cacaauccga uggcgacagc     1440

ucaaaaguua aaguaaaagu cagaguaaac auacauggaa uuuucucugu cgcaucagca     1500

ucuguuaucg aaaaacaaaa ucuagaaggg gaccauuccg acgccccaau ggaaaccgaa     1560

acaagcuuua aaaaugaaaa caaagacaau auggauaaaa ugcaaguaga ucaagaagaa     1620

ggacaucaaa aaugccaugc ugagcauaca ccagaagaag agauagacca cacuggggca     1680

aaaacaaaau cagccguuuc agauaaacaa gauagauuaa aucaaacacu aaaaaaaggc     1740

aagguaaaau cuauugauuu accaauccaa uccucacucu gcagacaauu aggacaagau     1800

cuauuaaaua gcuauauaga aaaugaagga aaaaugauca ugcaagacaa acuagaaaaa     1860

gaaagaaacg acgccaaaaa ugcaguugaa gaauacguau augauuucag ggaccgacua     1920

ggaaccguuu augaaaaauu uauaacgcca gaagaccuuu caaaacuaag ugcaguauua     1980

gaagacacag agaacugguu auaugaagau ggagaagacc aaccaaaaca aguauacguu     2040

gacaaauuac aagaacuaaa gaaauacgga caaccaauac aaaugaaaua cauggagcac     2100

gaagaacguc caaaagcacu aaacgaccua ggcaaaaaga uccaacuugu aaugaaagua     2160

auagaagcuu auagaaauaa agaugaacgg uaugaccauc uugaccccac agaaauggaa     2220

aaaguugaaa aaugcauaag cgacgcaaug agcuggcuca acagcaaaau gaacgcacaa     2280

aacaaauuau cacuaacaca agauccagua guaaaaguca gugaaauagu agcaaaauca     2340

aaagaacuag acaauuucug uaauccaaua auauacaaac ccaaaccaaa agccgaaguc     2400

cccgaagaca aaccaaaagc aaacucagaa cauaaugguc caauggaugg acaaucugga     2460

acagagacaa aaucagacuc aacuaaagau ucaucccaac auaccaagag uagcggggaa     2520

auggaagucg acuagggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  1992
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt6)

<400>  1992
gggagaaagc uuaccaugaa auuaaguuug guggcagcaa ugcuauuauu auuaagcgcu       60

gcaagagcag aagaagagga uaaaaaagaa gauguuggua cggugguugg aauugaccuu      120

ggaacaacau acagcugugu cggaguauuu aaaaauggaa gaguugaaau uauagcuaac      180

gaucagggga auagaauaac accaaguuac guagcauuca caccagaggg agaaagauua      240

aucggagacg cagcaaaaaa ccaacuuacu aguaauccag aaaauacagu auucgaugca      300

aaaagauuaa uaggaagaac auggaacgac ccuuccguac aacaagauau caaauuccua      360

ccauuuaaag uuguagaaaa aaagacaaaa ccauacauac aagucgauau aggaggagga      420

caaacaaaaa cauuugcgcc agaggaaauc agugcaaugg uauuaacuaa aaugaaagag      480

acagcagaag cauacuuagg uaaaaaagua acacacgcag uagucacagu accagcauau      540

uuuaacgacg cacaaagaca agcaacaaag gaugcaggaa caaucgcagg auuaaacgua      600

augagaauaa uaaaugagcc aacagcagca gcaauugcau auggauuaga caaacgagaa      660

ggugagaaaa acauccuggu auucgacuua ggagggggca cauuugacgu aaguuuauua      720

acuauagaua auggaguauu ugaaguagua gcaacaaacg gugacacaca uuuaggagga      780

gaagauuucg aucagagagu aauggaacau uuuauaaaau uauacaaaaa aaaaacagga      840

aaagauguaa ggaaagacaa uagagcagug caaaaacuua ggagagaagu cgaaaaagca      900

aaacgagccc uaaguagcca acaucaagca agaauagaaa uagaaagcuu uuaugaaggg      960

gaagacuuca gugaaacacu uacgagagca aaauuugaag aauuaaacau ggaccuauuu     1020

agaagcacaa ugaaaccugu acaaaaagug cucgaagauu cagaccuaaa aaaaagcgac     1080

auagaugaga uugucuuagu aggaggaagu acaagaauuc caaaaaucca acaacuagua     1140

aaagaauuuu ucaauggaaa agaaccuagu agaggaauaa acccagacga agcaguagca     1200

uauggagcug caguacaagc uggaguucua aguggcgacc aagacacagg agacuuagua     1260

uuacuagacg uauguccguu aacauuagga auagaaacag uaggaggagu aaugaccaaa     1320

uugauaccua ggaacacugu uguaccaacg aaaaaaucac aaauauuuag uacagcauca     1380

gauaaccaac caacuguaac uauaaaagua uacgaaggag aaaggccucu aacaaaagac     1440

aaucaccuuc ugggaaccuu ugaucucaca ggaauaccac cagcaccacg gggaguaccg     1500

caaauagaag uaacauucga aauagacguc aacgguauuc uaagaguaac ggccgaagau     1560

aaaggaacag gaaacaagaa uaagauaacu auuacaaaug accaaaaucg auuaacucca     1620

gaagaaauag aacgaauggu caacgacgca gaaaaauuug ccgaagaaga uaaaaaauua     1680

aaagagagaa uagauacucg aaacgaacua gaaaguuacg ccuacucacu caaaaaccaa     1740

aucggggaua aagaaaaguu aggagguaaa uuaucaagug aagauaaaga aacaauggaa     1800

aaagcagucg aagaaaaaau ugaauggcua gaaucacacc aagacgcaga uauagaagau     1860

uucaaagcaa aaaaaaaaga auuagaagaa auuguacaac ccauaauuag uaaauuauau     1920

ggaagugcag ggccaccacc aacaggcgaa gaagacacag cagaaaaaga ugaauuauaa     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  1993
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt6)

<400>  1993
gggagaaagc uuaccaugca agcaccaaga gaacuagcgg uaggaauaga uuuaggaaca       60

acuuacucau guguaggagu auuucaacaa ggaagaguag aaauauuagc aaaugaccaa      120

ggaaauagaa caacacccuc auacguagcc uuuacagaca ccgaacgauu aguaggagau      180

gcagcaaaaa gccaagcagc acucaaccca cauaauacgg ucuuugacgc aaaaagauua      240

auaggccgaa aauuugcgga uacuacagua caaagugaua ugaaacacug gcccuuucga      300

guaguaucug aaggaggaaa accgaaggua agaguauguu aucgaggaga agacaaaaca      360

uucuauccag aagaaauauc uucuauggua uugucgaaaa ugaaagaaac ggcugaagcg      420

uaucuaggac aaccaguaaa acaugcagua auaacuguac cagcuuacuu uaaugauagc      480

cagagacaag caacaaaaga ugcaggagcc auagcaggau uaaauguauu gaggauaaua      540

aaugaaccaa cugcagccgc aauagcauac ggguuagacc gaagaggagc cggugaaaga      600

aaugucuuaa uauuugauuu gggcggagga acauuugaug uaaguguauu aucaauagac      660

gcaggaguuu uugaagucaa agcaacggca ggagacacac auuuaggagg ggaagacuuu      720

gauaauaggc uaguaaauca uuucauggaa gaauuucgaa gaaaacacgg aaaagauuua      780

ucuggaaaua aacgagcuuu aagaagguua agaacagccu gugaaagagc aaaaagaaca      840

uuaucaucaa guacacaagc aacauuagaa auugacucac ucuucgaagg agucgacuuc      900

uauacaucaa uaacacgagc aagauuugaa gaacuaugcu cagaucuauu ucgaucaaca      960

uuagaaccag uggaaaaagc auugcgggau gcgaaauuag acaaagcaca aauacaugac     1020

guaguuuuag uaggcggcuc aacaagaaua ccaaaagugc aaaaacuauu acaagauuuc     1080

uucaacggga aagaauuaaa caaaucaauu aauccggaug aagcuguagc uuauggagca     1140

gcaguucaag ccgccgucuu aaugggagac aaaugcgaaa aaguucaaga uuuauuacua     1200

cuagaugugg caccacucuc ucuuggucuc gaaacagcgg gaggaguuau gacuacguua     1260

auccaaagaa augcaacaau uccaacaaaa caaacccaga cauucacaac auacucugau     1320

aaucaaccag gagucuuuau acaaguuuac gaaggcgaac gagcaaugac aaaagauaau     1380

aauuuauugg gaagauuuga acuuucagga auacccccag caccuagagg aguaccucaa     1440

auagaaguaa ccuucgacau agacgcuaau ggaauacuua gcguaacugc aacugauaga     1500

aguacaggaa aagcaaacaa aauaacaaua acaaacgaua aaggccgacu aagcaaagaa     1560

gaaguagaaa gaaugguaca ugaagcugaa caauacaaag ccgaagauga agcacaacga     1620

gauagaguug cagcuaaaaa uagucuagag gcacauguau uucauguaaa aggcagccua     1680

caagaagaga gcuuaagaga caaaauacca gaagaagaca gaagaaaaau gcaagauaag     1740

uguagagaag uauuggcaug guuagaacau aaucaauuag cagaaaaaga agaauaugaa     1800

caucaaaaac gagaauuaga acaaauaugu cgaccaauau uuucaagguu auauggaggc     1860

ccaggaguac cagggggaag uucauguggu acacaagcaa gacaagguga uccgucaaca     1920

ggaccaauca ucgaagaagu agacuaagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  1994
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt6)

<400>  1994
gggagaaagc uuaccaugca agcaccaaga gaauuagcug uaggaauaga cuuaggaaca       60

acauauuccu guguaggagu auuucaacaa ggaagaguag aaauuuuagc aaaugaucaa      120

ggaaauagaa caacaccauc auauguagca uuuacugaua ccgaaagauu agucggagau      180

gcagcaaagu cacaagcagc auuaaauccu cacaauacag uuuuugaugc aaaaagauua      240

auaggaagaa aauucgcuga uacaacagua caaagcgaca ugaaacauug gccauuccaa      300

guuguaagcg aagguggaaa accaaaagua cgaguauguu auagaggaga agacaaaaca      360

uucuaccccg aagaaauauc aaguaugguu cuaucaaaaa ugaaagaaac agcagaagca      420

uauuuaggac aaccaguuaa acaugcagua auaaccguuc caacauauuu uagcaauagu      480

caaagacaag caacuaaaga ugcaggagca auagcaggac uuaaaguacu gccaauaaua      540

aaugaagcaa cagcagcagc aauagccuau ggccuagaca gaagaggagc uggaaaaaga      600

aacguauuaa uauuugauuu aggaggagga acuuuugaug uaaguguauu aaguauugac      660

gcaggcguuu uugaaguaaa agcaacugcu ggugauacuc acuugggugg agaagauuuu      720

gauaauagau uaguaaauca uuuuauggaa gaauuuagaa gaaaacacgg aaaagaucua      780

aguggaaaua aaagggcauu gagaagauua agaacagcau gugaaagagc aaaaagaaca      840

ccuagcucaa guacacaagc aacgcuagaa auagauucau uauucgaagg aguagauuuu      900

uauaaaucaa ucacaagggc aagauuugaa gaauuaugca gugacuuauu caggagcaca      960

uuagaaccag uagaaaaagc auuaagagau gcaaaauuag auaaagcaca aauacaugau     1020

uuugugcuag gagggggauu acauucacau ccacaaggag cagaaguugc agcaggauua     1080

uuacaaagac aaggagcaga acaagaacac caaccauaag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  1995
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt6)

<400>  1995
gggagaaagc uuaccaugag caaagggcca gcaguaggaa uagauuuagg uaccaccuac       60

agcuguguag gaguauucca acacggaaaa guggaaauaa uagcaaauga ccaaggcaau      120

aggacaacac caucauacgu ugcauucaca gauaccgagc gacuaauugg agaugcagcu      180

aaaaaucaag uagcaaugaa uccaacaaau acgguauuug acgcaaaaag acuaauaggc      240

aggagguuug augacgcagu uguacaaagc gauaugaaac acuggccauu uaugguagua      300

aaugaugcug gaagaccaaa aguacaagua gaauacaaag gcgaaacuaa aaguuucuac      360

cccgaagaag uaucuucaau gguauuaaca aaaaugaaag aaaucgcaga agcauacuua      420

ggaaaaacgg uuacaaacgc aguaguaaca guaccagcau auuuuaacga cucccaaagg      480

caagcaacaa aagacgcugg gacaauugcc gggcuuaaug uauuaagaau cauaaaugaa      540

ccaacagcag cagcaauagc cuacggauua gauaagaaag uaggugcaga aagaaacgua      600

uuaauauuug acuuaggcgg uggaacauuu gauguaucaa uauuaacaau agaagacgga      660

auauuugaag uaaaaucuac agcuggagac acacaccuag gaggagaaga uuucgauaac      720

agaaugguaa aucauuuuau agccgaauuu aaaaggaaac auaagaaaga uauaagugaa      780

aauaaaagag caguaagaag auuaagaaca gcaugcgagc gagcgaaaag gacuuuauca      840

ucgagcacac aagcaagcau agaaauugau agccuauaug aagguauaga cuuuuacaca      900

ucaauaacaa gagcccgauu cgaagaauua aacgcagauc uauuuagagg aacguuagac      960

ccaguagaaa aagcauuaag agaugcaaaa uuagauaaaa gccaaauaca ugacaucgua     1020

uugguuggag gaucuacaag aauaccuaaa auacaaaaau uacuacaaga cuucuuuaac     1080

ggcaaagaau uaaacaaauc aauaaaucca gacgaagcag uagcguaugg ugcggcggua     1140

caagccgcua uauuauccgg agacaaaagu gaaaacguac aagaucuacu auuacuagac     1200

guaacacccc uaucauuagg aauugaaaca gcaggaggag uaaugacagu uuuaauaaaa     1260

agaaauacaa caauaccaac uaaacaaacc caaacauuua caacuuacag ugacaaucaa     1320

ccaggagugc ucauacaagu uuacgaagga gaacgagcaa ugacaaaaga caacaaucua     1380

uuaggaaaau uugaacuaac cggaauacca ccagcaccua gaggcgugcc acaaauagaa     1440

gucacauuug acauagaugc aaauggaaua cuaaacguca gcgcagucga uaaaucaaca     1500

ggaaaagaaa acaaaauaac cauaacaaac gacaaaggac gccugagcaa agaagauauc     1560

gaacgaaugg uacaagaagc agaaaaauau aaagcggagg acgaaaaaca acgagacaaa     1620

guaagcagua aaaacagcuu agaaucauau gcauuuaaua ugaaagcaac uguagaagac     1680

gaaaaauuac aaggaaaaau aaacgaugaa gauaaacaga aaauacuaga caaauguaac     1740

gagauaauaa auuggcugga caaaaaucaa acggcagaaa aagaagaauu ugaacaucaa     1800

caaaaagagc uugaaaaagu uuguaaucca auaauaacaa aacuauauca aagugcagga     1860

ggaaugccag gaggaaugcc cggaggauuc ccuggaggag gcgcaccccc aaguggagga     1920

gccaguucag gcccaacaau agaagaagua gauuagggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  1996
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt6)

<400>  1996
gggagaaagc uuaccaugau aucagcaagc agagcagcag cagcaagacu ugugggagca       60

gcagcaucaa gaggaccuac agcagcaagg caucaagauu cguggaaugg guuaagccau      120

gaggcguuua gacuuguguc uaggagagau uacgccagcg aagcaauuaa aggugcgguu      180

guaggaauag aucuaggaac gacaaacuca uguguagcag ucauggaagg aaaacaagca      240

aaagugcuag aaaaugcaga aggcgcaaga acaacaccau caguaguugc auuuacagca      300

gauggagaaa gguuaguugg uaugccagca aaaagacaag caguaacaaa uccgaacaau      360

acauuuuacg cuacaaaaag guuaauagga agaagauacg augacccaga agugcaaaaa      420

gauauuaaaa auguaccuuu uaaaauaguc agagcaucua auggugaugc auggguagag      480

gcccacggaa aacucuacuc uccaagucaa auaggagccu ucguauuaau gaagaugaaa      540

gaaacagcug aaaauuauuu aggacacaca gcgaaaaaug caguaauaac gguaccagca      600

uacuucaacg acagucaaag acaggcaaca aaagacgcag gacaaauaag uggauuaaac      660

guauuaagag uaauaaauga accuacagca gcagcauuag cauauggccu agauaaauca      720

gaagacaaag uaauagcggu auaugauuua ggcggaggaa cauuugacau uucaauauua      780

gagauacaaa aagguguauu ugaaguuaaa aguacaaaug gugacacauu uuugggagga      840

gaagauuucg aucaagcacu acuucgacau auaguuaaag aguuuaaaag agaaacaggg      900

guagaucuca cuaaagauaa uauggcauug caaaggguaa gggaagcagc ugaaaaagca      960

aagugcgagc uaagcucauc uguacaaacg gauauuaauc uaccauauuu aacaauggac     1020

agcucagguc caaaacaucu caauaugaaa uuaacaagag cucaauucga aggaauagua     1080

acggacuuaa uaagaagaac uauagcacca ugucaaaaag cuaugcagga ugcggaagug     1140

agcaagagug acauaggaga aguuaucuug guagguggaa ugacaagaau gccaaaaguu     1200

caacagacag uacaagaucu auucgggaga gcuccuagua aagcuguuaa uccagacgaa     1260

gccguagcca uaggagcagc aauacaagga ggaguauuag caggagaugu aacugaugua     1320

cuacuauuag auguaacacc guugagccuu ggaauagaaa cuuuaggagg aguguucacu     1380

aaauuaauca auagaaauac aacgauaccu acgaagaaau cacaaguauu caguacagca     1440

gccgaugggc aaacacaagu agaaauaaaa gucugccaag gagaaagaga gauggcagga     1500

gauaauaaau uguuagggca auuuacauua auagguauac cuccagcacc gagaggagua     1560

ccucagauag aaguuacauu cgauauagau gcaaauggua uaguucaugu aucagcaaaa     1620

gacaaaggaa cuggaagaga acaacaaaua gugauacaaa gcaguggagg acuaaguaaa     1680

gaugauauag aaaacauggu uaaaaacgcg gaaaaauaug cagaagaaga uagaagaaag     1740

aaagagagag uagaagcagu uaacauggcu gaaggaauaa uacaugacac ugaaacaaaa     1800

auggaagaau uuaaagauca gcuaccagca gaugaaugua auaaacuaaa agaggaaaua     1860

aguaaaauga gagaauuguu agcuagaaaa gacagugaga cuggagaaaa uauuagacaa     1920

gcagcaagcu cauuacaaca agcaagccuc aaauuauuug agauggcaua uaagaaaaug     1980

gcaucagaaa gggaaggauc cggaucaagc ggaacgggag aacaaaaaga agaucaaaaa     2040

gaagaaaaac aauagggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  1997
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt6)

<400>  1997
gggagaaagc uuaccauggc agacaaagaa gcaggcggaa gugaugggcc aagagaaaca       60

gcaccaacau cagcauacag uucaccagca agaagccuag gagacacagg aauaacccca      120

uuaaguccau cgcacauugu aaacgacaca gacuccaacg uaagcgaaca acaaaguuuc      180

cuaguaguag uagcuguaga uuuuggaacc acaucaucag gauacgcaua cucauuuaca      240

aaagaaccug aauguauaca ugucaugaga agaugggaag gcggagaucc uggaguaagu      300

aaucaaaaaa cuccaacaac aauacuucuc acaccagaac gaaaauucca cucauuugga      360

uaugcagcca gagacuuuua ccacgauuua gauccaaaug aagcaaaaca augguuauac      420

cuagaaaaau ucaaaaugaa acuucauacc acuggagauu uaacaaugga cacagaccua      480

acagcagcca auggaaaaaa aguaaaagca cuagagauau uugcauacgc acuacaauac      540

uuuaaagaac aagcacuaaa agaauuaagc gaccaagcag guuccgaauu ugaaaauuca      600

gacguaagau ggguaauaac aguccccgca auauggaaac aacccgccaa gcaauuuaug      660

agacaggcag cauaccaagc gggacuagcc uccccagaaa acucagaaca acuaauuaua      720

gcacuugaac cagaggcagc gucaauauau uguagaaaac uacgauuaca ucaaaugaua      780

gaauuaaguu caaaagcagc aguaaaugga uacucaggau cagauacagu gggagcagga      840

uuuacacaag cuaaagaaca uauuagaaga aacagacaaa gcagaacauu ucuuguagaa      900

aacgucauag gagaaauaug guccgaacua gaagaaggag auaaauaugu aguaguugac      960

agcggaggag gaacaguaga ucuaacuguc caucaaauca gacuacccga agggcacuua     1020

aaggaacuau acaaagcaac gggaggccca uacggcucau uaggaguuga cuacgaauuc     1080

gaaaaauuau uauacaaaau auucggagaa gauuuuauag aacaauuuaa aaucaaaagg     1140

ccugcagcau ggguagauuu aaugauagca uuugaaagca gaaaaagagc cgcagcaccc     1200

gauagaacaa acccacuaaa uauaacacua ccguucucau uuauagauua cuauaaaaaa     1260

uuuagaggac auucgguaga acaugcacua agaaaaagca acguugacuu ugucaaaugg     1320

agcagucaag gaauguuacg gaugagccca gaugcaauga augcacuauu caaaccaaca     1380

auagauagua ucauagaaca uuuaagagau uuauuucaaa aaccagaagu caguacagua     1440

aaauuccuau ucuuaguagg cggauucgca gaagcacccc uauuacaaca agccguacaa     1500

gcagcauucg gagaucaaug uagaauaaua aucccacaag augucggacu cacaauacuc     1560

aaaggagcag uucuauucgg acucgaccca gcaguaauua aaguaagaag aucaccacuu     1620

accuauggug uugguguauu aaauagauau guagaaggaa aacacccucc agaaaaauua     1680

uuaguaaaag auggaacaag auggugcacu gacguauuug auaaauuuau uucggcagac     1740

caaucaguag cucuagguga acuuguaaaa cgauccuaua caccugcaaa accaucacaa     1800

cuagucauag uaauaaauau auacuccuca gaacacgaua augucucauu uaucacugac     1860

ccaggaguaa aaaaaugugg cacauuaaga uuagauuuga cagguacaag ugguacugca     1920

guacccgcac gaagagaaau ccagacauua augcaauuug gcgacacaga aaucaaagcc     1980

acagcaauag acauagccac aucuaaauca guaaaaguag gaauagacuu cuuaaauuau     2040

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  1998
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt6)

<400>  1998
gggagaaagc uuaccaugcu ugcaguucca gaaaugggac uacaaggacu auauauaggc       60

aguucaccag aacgaagucc gguacccagu ccaccgggau caccaaggac acaagaaagu      120

ugcggaauag caccucuaac accuagccaa ucaccuaaac cugaagugag agcaccacaa      180

caagcgaguu ucucgguugu aguagcaaua gauuucggaa caacaucaag ugguuaugca      240

uuuucauuug cuucagaucc agaagcuaua cauaugaugc gaaaauggga aggaggcgau      300

ccuggcguag cacaucagaa aaccccuacu ugucuauugc uaacaccaga aggagcauuu      360

cauaguuuug gauauaccgc ucgagauuac uaucaugacu uagauccaga agaagcaagg      420

gauugguuau acuuugaaaa auuuaaaaug aaaauacaua gugccacgga ucuaacauua      480

aaaacacaau uagaagcagu aaauggaaaa acaaugccag cauuagaagu auuugcacac      540

gcauugagau ucuuucgcga acaugccuua caagaacuac gcgaacaauc cccuuccuua      600

ccagaaaagg auacuguacg auggguauua acaguccccg cuauauggaa acaaccggcu      660

aaacaauuua ugagagaagc agcauauuug gcuggccuag ucagccggga aaacgcugaa      720

caauuacuaa uagcauuaga accagaagcu gcaagcguau acuguagaaa acuaagacuu      780

caucaauuac uagaucuaag cggaagggca ccuggaggag ggcgauuagg agaaagaaga      840

ucuauagauu caucauuuag acaagcuaga gaacaauuaa gaagaucacg ucacucaaga      900

acauuucuag uugaaucagg uguaggcgaa cuuugggcag aaaugcaagc aggagacaga      960

uauguagugg cugacugcgg aggggguaca guugaccuaa caguacauca auuagaacaa     1020

ccacacggaa cacuaaaaga auuauauaag gcuucaggag gaccauacgg ggcaguagga     1080

guugaucuag cuuuugaaca acuacuuugu cgaauauucg gugaagauuu uauagcaaca     1140

uuuaaaaggc aaagaccugc ugcaugggua gaucuaacua uagcauucga ggcaagaaaa     1200

cgaacagcag gaccacauag agcuggugcu uuaaacauuu cauuaccauu uucauucaua     1260

gauuuuuaca gaaaacaaag aggacauaau guagaaacag cauuaagaag aaguucagua     1320

aauuuuguaa aauggucuag ucaaggaaug cuaagaaugu caugcgaagc uaugaacgaa     1380

cuauuucaac ccacaguauc cgguauaaua caacauauag aagcacuauu agcuagaccu     1440

gaaguacaag gaguaaaauu auuauuuuua guaggaggau ucgcagaauc agcuguguua     1500

caacaugcug ugcaagcagc guugggcgcu agaggucuaa gaguaguagu uccucacgau     1560

guaggacuaa caauacuaaa aggagcagua uuauucggcc aagcgccugg aguaguucga     1620

guaagaagau cuccauuaac auauggugug ggaguauuaa auagauucgu gccagguaga     1680

cauccaccag agaagcuauu aguaagagau ggcaggaggu gguguacuga ugucuucgaa     1740

agguuuguug cagccgaaca aagcguugca cuaggagaag aaguuagaag aucauacugu     1800

ccagcacggc caggacaaag aagagugcua auuaacuuau auuguugcgc agcagaagau     1860

gcaagauuua uuacagaccc agguguaaga aaguguggag cccucaguuu agaacuugaa     1920

ccagcugauu gcggccaaga uacagcaggc gcacccccag gcagacgaga aauaagagcg     1980

gcaaugcaau uuggagauac agaaauaaaa guuacagcug uagauguaag cacaaacaga     2040

aguguuagag caucaauaga cuuucuaagu aacuaaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  1999
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt6)

<400>  1999
gggagaaagc uuaccauggc uagagaaaug acaauacucg gcucugcagu auuaaccuua       60

cuauuagcag gauauuuagc acaacaauac cuucccuuac caacaccaaa aguaauaggu      120

auagaucucg guacaacaua uuguuccguc ggaguuuucu uuccaggaac cggaaaaguu      180

aaaguuauac cagacgaaaa uggacacaua uccauaccaa guaugguaag uuuuaccgac      240

aacgauguau augucgguua cgaaagcgua gaauuagcag auaguaaucc acaaaacaca      300

auauaugacg caaaaagauu cauaggaaaa aucuucaccg cagaagaacu ggaagcagaa      360

auaggaagau auccauucaa aguacuaaau aaaaauggaa ugguagaauu cucaguaacu      420

uccaaugaaa caauaacagu aucaccagaa uaugucggcu caagauuauu auuaaaauua      480

aaagaaaugg cagaagcaua cuuaggaaug ccaguagcaa acgcaguaau cucaguacca      540

gccgaauucg auuuaaaaca aagaaauucc acuauagaag cagcaaaucu agcaggucuu      600

aaaauauuaa gaguaauaaa ugaacccaca gcagcagcaa uggcauaugg acuacacaaa      660

gcagauguuu uucacguacu agugauagau uuaggaggcg gcacauuaga cguaagucua      720

cucaauaaac aaggcgguau guuucuaaca agagccauga guggaaacaa caaauuagga      780

ggacaagacu uuaaccaaag acuacuacaa uauuuauaca aacaaauuua ccaaacauau      840

ggauucgucc caucaagaaa agaggaaauc cacagacuaa ggcaagcagu agagaugguc      900

aaacuaaacu uaacauuaca ucaaucagca caacuaucag ucuuauuaac aguagaagag      960

caagauagaa aagaaccuca cuccagugac acagaacucc cuaaagauaa acuaucauca     1020

gcagaugacc accgagucaa caguggauuc ggaagaggcc uaagugacaa aaaaagcgga     1080

gaaucacaag uauuauuuga aacugaaauu agcagaaaac uauuugauac auuaaaugaa     1140

gaccuauuuc aaaaaauacu aguaccaaua caacaaguac ucaaagaagg acauuuagaa     1200

aaaacagaaa uagacgaagu aguacuagua ggaggaagca cacgaauucc uagaauaaga     1260

caaguaauac aagaauuuuu cggcaaagac ccuaauacau caguagaccc agaucuagcc     1320

gucguaacag gaguagcaau acaggcagga auagauggag gaagcuggcc acuucaaguc     1380

agugccuuag aaaucccaaa caaacauuua caaaaaacca auuucaacua aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2000
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt6)

<400>  2000
gggagaaagc uuaccauggc agcaauagga guacaccuag gauguacauc agcaugugua       60

gccguauaua aagaugguag agcaggaguu guggccaaug augccggaga uagaguaacu      120

ccugcaguag uugcauacag cgaaaaugaa gagauaguug gacuagcugc aaaacaaagc      180

agaauaagaa auauaaguaa uacaguaaug aaagucaaac aaauauuagg aagaucaagu      240

ucagacccuc aagcucaaaa auacauugcu gaaagcaaau gucuaguaau agagaaaaau      300

ggaaaacuaa gauaugaaau ugauacgggu gaagaaacua aauucguaaa cccagaagau      360

guagcaagac uaauauuuag uaaaaugaaa gaaacagcuc auucaguauu aggaucagac      420

gcaaaugacg uaguaauaac uguaccauuc gauuuuggag aaaaacaaaa gaacgcuuua      480

ggagaagcgg cuagagcagc agguuuuaau guauuaagac uaauacauga accauccgcu      540

gcacuauuag cauacggaau aggacaagau aguccaacag guaaaucaaa uauccuagua      600

uucaaauuag gaggaacauc auuaucguua ucaguaaugg aaguaaauag ugggauauau      660

agaguauuga gcacaaauac agaugauaau auaggcggag cacauuuuac agaaacucua      720

gcacaauauc uagcaaguga auuucaaaga aguuuuaaac augauguucg aggaaaugca      780

agagcaauga ugaaauuaac aaauucagcg gaaguagcaa aacacucauu aagcacguua      840

gguagugcaa auuguuucuu agauaguuua uaugaaggac aagauuuuga uuguaaugua      900

ucacgagccc gauuugaauu auuauguagc ccucuauuua auaaauguau agaagcaaua      960

aggggauuac ucgaucaaaa uggauucaca gcugaugaua uaaauaaagu aguauuaugu     1020

ggagguucaa guagaauacc uaaauuacaa caacuaauaa aagacuuauu uccagcagua     1080

gaacugcuaa auaguauacc gccagacgaa guaauaccaa uaggagcagc aauugaagcc     1140

ggaauacuaa uuggaaaaga aaaucuauua guagaagaca gccuuaugau agaauguagu     1200

gcaagagaca uacucgucaa aggcguagau gaauccggag caaguagauu cacuguauua     1260

uucccaucag gaacgccacu accagcaaga agacaacaua cacuacaagc accaggaagc     1320

auaucaagug uaugucuaga acuauaugaa ucagacggga aaaauagcgc aaaagaagaa     1380

acaaaauuug cacaaguagu auuacaagau uuagacaaga aagaaaaugg auuaagagau     1440

auauuagcag uauuaacuau gaaacgagac ggaagucuac auguaacaug uacagaucaa     1500

gagacaggaa aaugugaagc gauaucaaua gaaauugcua gcuaaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  2001
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt6)

<400>  2001
gggagaaagc uuaccauguc aguaguagga cuugauguag gaucacaauc auguuauaua       60

gcaguagcac gagcaggagg uauagaaaca auagcaaaug aauucagcga uagauguaca      120

ccuucaguca uaucuuucgg aucaaagaau cgaaccauug gcguagccgc aaaaaaccaa      180

caaaucacgc acgcuaacaa uacaguauca aacuuuaaaa gauuucacgg ucgagcguuu      240

aaugaccccu ucauucaaaa agaaaaagaa aacuuaagcu augaccuugu accacuuaaa      300

aauggaggag uaggcauuaa aguaauguac augggagaag aacaccuauu uaguguagaa      360

caaaucaccg cgaugcuacu aacaaaacua aaagaaacag cagagaauag ccuaaaaaaa      420

ccaguuacug acugcguaau aaguguacca ucuuucuuua ccgacgcaga aagacggucc      480

guucuagaug cagcccaaau aguaggauua aacugucuca gacuaaugaa ugauaugacu      540

gcaguggcuc uaaauuaugg aauauauaaa caagacuugc caucacuaga ugaaaaacca      600

agaaucguag ucuucgucga uaugggccau agcgcauuuc aaguuucagc augugcuuuc      660

aacaaaggaa aacugaaagu ucuaggaacg gcauucgauc cauuucuagg gggaaaaaau      720

uuugacgaaa aauuaguaga acacuuuugc gccgaauuca aaacaaaaua caaacuagac      780

gcaaaaagua aaauaagagc auuauugaga uuauaccaag aaugcgaaaa acuaaaaaaa      840

uuaaugagcu ccaacucaac agacuugcca uuaaacauag aaugcuucau gaaugauaaa      900

gacguauccg guaaaaugaa uagaucccag uucgaggaac uaugugccga acuacuucaa      960

aaaauagaag uaccauuaua cucacuauua gaacaaacuc accuaaaagu cgaagacgua     1020

agugcaguag aaauuguagg uggagcaaca agaauaccgg cuguaaaaga aagaauagca     1080

aaauucuuug gaaaagauau aucaacaaca uuaaacgccg augaagccgu agcuagaggg     1140

ugcgcacuuc aaugcgccau auuaucacca gcguuuaaag ucagagaauu caguguuacc     1200

gaugcaguac cauucccaau aaguuuaaua uggaaccaug acucagaaga caccgaagga     1260

guucaugaag uauuuagccg aaaccacgcc gcaccauuua guaaaguauu aacauuucua     1320

agacgugguc cauuugagcu ugaagcauuu uauucugauc cacaaggagu accauaccca     1380

gaagcaaaaa uaggcagauu ugucguacaa aacguaucgg cacaaaaaga uggagaaaaa     1440

ucacgaguca aaguaaaggu gagaguaaac acacauggaa uauucacaau aaguacagcc     1500

agcauggugg aaaaaguucc aacagaagaa aacgaaauga gcagcgaagc agauauggaa     1560

ugucuaaacc aaagaccgcc agaaaaccca gacacagaua agaaugucca acaagacaac     1620

ucugaagcag gcacucaacc acaaguucaa acagaugcac aacaaacuuc acaaucacca     1680

ccgucuccag aauuaaccag ugaagaaaac aaaauacccg acgcagauaa agcaaacgaa     1740

aaaaaaguag accaaccacc agaagcaaag aaaccaaaaa uuaaagucgu gaacguagaa     1800

uuaccaauag aagcaaaucu aguauggcaa uuaggcaaag accuauuaaa uauguauauc     1860

gagaccgaag guaaaaugau aaugcaagac aaauuagaga aagaacgaaa ugaugcaaaa     1920

aaugcaguag aagaauaugu auaugaauuu agagauaaac uauguggacc guacgaaaaa     1980

uuuauaugug aacaagacca ucaaaauuuu cuacgacuuc uaacugagac agaagacugg     2040

cuauacgaag aaggagaaga ucaagcaaaa caagcguaug uagacaaacu agaagaauua     2100

augaagauag guacaccagu aaaaguacga uuccaagaag cagaagagag accaaaaaug     2160

uuugaagaac ugggucaaag auuacaacac uaugcaaaaa ucgccgcaga cuuucgaaac     2220

aaagacgaaa aguauaauca uauagaugaa ucagaaauga aaaaagucga aaaaaguguc     2280

aacgaaguga uggaguggau gaauaacguu augaaugcac aagccaaaaa aagccuagau     2340

caagauccug uaguaagagc acaagagauc aaaaccaaaa uaaaagaacu aaauaacacc     2400

ugcgagccag ugguuaccca gccaaaacca aaaauagaaa gucccaaauu agagagaacc     2460

cccaauggac caaauauaga uaaaaaagaa gaagaccuag aggauaaaaa uaacuucgga     2520

gccgaaccac cacaccaaaa uggggaaugu uaccccaacg aaaaaaauag uguaaacaug     2580

gauuuagacu aaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  2002
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt6)

<400>  2002
gggagaaagc uuaccauggc ugauaaaguc agacgacaac ggccaagaag aaggguaugc       60

ugggcacugg uagcaguucu gcuagccgau uuauuagcgu uaucagauac ccuagcugua      120

augagcguag acuuaggcag ugaaaguaug aaaguggcaa uaguaaaacc aggaguaccc      180

auggagauug uuuuaaauaa agaaucaaga agaaagacgc caguaauagu aacgcuaaaa      240

gagaacgaaa gauucuuugg agacucagca gcaaguaugg caauuaaaaa cccaaaagca      300

acccugagau acuuucaaca ucuguugggc aaacaagcag acaacccaca uguagcgcua      360

uaccaagcga gguuuccuga acacgaacua acauucgacc cacaaagaca aacaguacac      420

uuccaaauau cuucacaacu ccaauuuuca ccugaggaag uacuuggaau ggucuuaaac      480

uacagucgaa guuuggcgga agauuuugcc gaacaaccua uaaaagaugc aguaauaaca      540

guaccuguau ucuuuaauca agccgagagg agagcuguau uacaagcugc aagaauggcu      600

ggacuuaaag uacuacaacu cauaaaugac aauacagcua cugcacuauc auaugguguu      660

uuuagaagaa aagacauaaa cacaacugca caaaauauca uguuuuacga uaugggaagc      720

ggaagcacag ucugcacuau agucaccuau cagaugguga aaacaaaaga agcaggaaug      780

cagccucaau uacaaauaag aggaguaggu uuugacagaa cgcugggugg auuagaaaug      840

gaacugagau uaagagaacg auuggcagga cuauucaaug agcaacgaaa gggucagaga      900

gcuaaagacg uuagagaaaa uccucgcgca auggcuaaac uuuuacgcga agcaaauaga      960

uuaaagacag uacuuagugc aaacgcagac cauauggcuc aaauagaagg acuaauggau     1020

gacguagacu uuaaagcaaa aguaacacga guagaguucg aagaacuaug ugcagaucuc     1080

uuugaaagag uaccuggucc aguacaacaa gcucuacaaa gugcugaaau gucuuuagac     1140

gaaauugaac aaguaauauu ggucggcgga gcaacacgag uuccuagagu acaagaagua     1200

uugcuuaagg caguaggaaa agaagaacua gggaaaaaua uaaacgcuga cgaagcagca     1260

gcaaugggag ccguuuacca agcggcagca cuaagcaagg cuuuuaaagu uaaaccauuu     1320

guaguaagag augcaguugu auauccaauu uuaguagaau uuacucgaga aguagaagaa     1380

gaaccaggga uacacucacu aaaacacaac aaaagaguac ucuuuagcag gaugggaccg     1440

uauccacaac guaaagucau aacauuuaac agauauucuc augauuuuaa uuuccauaua     1500

aacuacggag acuuaggcuu uuuaggucca gaagaucuaa ggguauuugg uucacaaaau     1560

cucacaacgg uuaaacuaaa agggguagga gauaguuuca agaaauaccc agacuaugaa     1620

ucuaaaggaa uaaaagcaca uuuuaaucua gaugaaagug ggguauugag ucuagaccga     1680

gucgagagcg uauucgaaac ucugguugaa gauagugccg aagaggaauc aaccuugacu     1740

aaacuaggua auacgauaag cagcuuauuc ggagguggca caacaccaga ugcaaaagaa     1800

aauggaacag acacaguaca ggaagaagaa gaaagcccgg cagagggcuc aaaagaugaa     1860

ccuggggaac aaguagaguu aaaagaagaa gcagaagcac caguggaaga cgguucgcaa     1920

ccaccucccc cagagccaaa aggugaugca acaccagaag gcgaaaaagc aacagaaaaa     1980

gaaaaugggg auaaaucaga agcacaaaag ccaagugaaa aagcagaagc uggaccagaa     2040

ggaguugcuc cugcaccaga aggagaaaag aaacaaaaac ccgcacgcaa aagaagaaug     2100

guagaggaaa uaggugucga gcuaguagua uuagaucuac cagaucuccc agaagacaaa     2160

uuggcacaaa guguacaaaa acugcaggac uuaaccuuaa gagacuuaga aaaacaagaa     2220

agggaaaaag cugcaaauuc uuuggaagca uucauauucg aaacacagga caaauuauau     2280

caacccgaau aucaggaagu auccacagaa gaacaaagag aagaaauauc aggaaaacuc     2340

ucagcagcau caacgugguu ggaagaugaa ggaguaggug caacaacagu aauguuaaaa     2400

gaaaaauuag cagaacuaag gaaacugugc caaggauuau uuuucagagu cgaagaaaga     2460

aagaaauggc cagaacgguu aucugcauua gauaauuuac uaaaccacuc uaguauguuu     2520

cuaaaagggg ccagauuaau accagaaaug gaucaaauuu uuacugaagu agaaaugaca     2580

acacuagaaa aaguaaucaa cgaaacaugg gcauggaaaa augcaacuuu agcagaacaa     2640

gcaaaauuac cggcaacaga aaaaccaguc uuacuaucaa aagacauaga agcgaaaaug     2700

auggcauuag acagagaagu ccaauaccua cuaaacaaag caaaguucac aaaacccaga     2760

ccgcggccaa aagauaaaaa cggaacccga gccgagccac cacuaaaugc aagcgcaagu     2820

gaucaagggg agaagguaau accgccugca ggacaaacag aagacgcaga accaaucucc     2880

gaaccagaaa aaguagaaac aggaucggaa ccuggagaua cagaaccccu agaauuagga     2940

ggaccuggag cugagccaga acaaaaagaa caaaguacag gacaaaaacg accucuuaaa     3000

aaugacgaac uauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2003
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt6)

<400>  2003
gggagaaagc uuaccaugcc agaagaaacc caaacacaag accaacccau ggaagaagag       60

gaaguagaaa cauucgcuuu ccaagcagaa auugcacaau uaaugagucu aauuauaaac      120

acauucuacu caaacaaaga aauauuuuua cgcgaacuaa uaagcaacuc aagcgaugca      180

uuagauaaaa uuagauauga aucguuaaca gauccaagca aauuagacuc aggaaaagaa      240

uuacacauaa aucuuauccc aaacaaacaa gauagaacac uuaccauagu cgacaccgga      300

auaggaauga caaaagcuga ccuaauaaac aauuuaggua caauagcaaa aucggguacc      360

aaagcauuca uggaagcacu acaagcaggu gccgacaucu cgaugauagg acaauuugga      420

guaggauucu acagcgcaua ccuaguagca gagaaaguaa caguuauaac aaagcacaac      480

gacgacgaac aauacgccug ggaaucaagu gcaggaggau cauucacagu aagaacagac      540

acaggugaac caaugggcag agguacgaaa guaauacuuc aucuuaaaga agaccaaaca      600

gaauaccuag aggaaagaag aaucaaagaa auaguaaaaa aacacucaca auucauagga      660

uauccaauaa cacucuuugu agagaaagaa agagacaaag aagucaguga cgaugaagca      720

gaggaaaaag aagauaaaga agaagaaaaa gaaaaagaag aaaaagaaag ugaagacaaa      780

ccagaaauag aagacguagg aucggaugag gaggaagaaa aaaaagaugg agacaaaaaa      840

aaaaagaaaa aaauaaaaga aaaauacaua gaucaagaag aacugaacaa aaccaaacca      900

auauggacaa ggaaccccga cgacaucaca aacgaagaau acggagaauu uuacaaauca      960

cuuacaaaug acugggaaga ccaccucgcc gucaaacacu uuagcguaga aggucaauua     1020

gaauucagag cccuacuguu uguaccuaga agagcaccau ucgauuuguu ugagaauaga     1080

aaaaaaaaaa auaauaucaa acuauacgua agaagaguau uuauaaugga caauugcgaa     1140

gaauuaauac cagaauaucu aaauuuuauc aggggaguag ucgacagcga agauuuacca     1200

uuaaacauau cgcgagagau guuacaacaa ucaaaaauuc ugaaaguaau aagaaaaaau     1260

cuagucaaaa aaugucuaga acuauucaca gaacuagcag aagacaaaga aaacuacaaa     1320

aaauucuaug aacaauucuc aaaaaauaua aaauugggca uacacgaaga cucucagaau     1380

agaaaaaaac uaucagaauu acuaagauau uauacgucag cuaguggaga cgagauggua     1440

ucccuaaaag acuacugcac aaggaugaaa gaaaaucaaa aacauauaua cuacauaacu     1500

ggagaaacca aggaccaagu cgcaaacuca gcauucguag aaagauuacg aaagcaugga     1560

cuggaaguaa uauacaugau agaacccaua gaugaauauu gcguacaaca auuaaaagaa     1620

uucgaaggaa aaacuuuagu aagcguaacg aaagaaggac uagaauuacc cgaagaugaa     1680

gaagagaaaa aaaaacaaga agagaaaaaa accaaauucg aaaacuuaug uaaaauaaug     1740

aaagacauau uagaaaaaaa aguagaaaaa guuguaguau caaacagacu aguaacaagc     1800

ccauguugca uaguaacaag uaccuacggg uggacggcaa acauggaaag aauaaugaaa     1860

gcccaagcuu uacgagacaa uaguacgaug ggauacaugg cagccaaaaa gcauuuagaa     1920

auaaacccag accacagcau aaucgaaaca cuuagacaaa aagccgaagc ugauaaaaac     1980

gacaaauccg ugaaagaccu cgucaucuua cuuuaugaaa cagcauuauu aaguagugga     2040

uucucccuag aagacccgca aacacacgcu aaucgaauau accgaaugau uaagcucgga     2100

uuaggaauag acgaagauga cccaacagcg gaugauacaa gcgcagcagu aacugaagag     2160

augccaccau uagaaggaga ugaugauacg ucaaggaugg aagaagucga cuaaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  2004
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt6)

<400>  2004
gggagaaagc uuaccaugga cucaagcaaa cuagacagcg gaaaaggacu acacauaaac       60

uuaguaccaa acaaacaaaa ccaaacacua acaauaguag acacaagaau aggaaugaca      120

aaaacagacu uaauaaacaa ccuaggaaca guaacaaaau caggaacaaa agcauucaug      180

gaagcacuac aagcagacgc agacauauca augauaggac acuucggagu aggauucuac      240

ucagcauacc uaguagcaaa aaaaguaaca guaauaucaa aacacaacaa cgacgaacaa      300

uacacauggg aaucaucagc aggaggauca uucacaguaa gaacagacga auaaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  2005
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt6)

<400>  2005
gggagaaagc uuaccaugcc cgaagaagug caucauggcg aagaggaggu agaaacauuc       60

gcuuuucaag cugaaauagc ucagcuaaug agccuaauaa uaaacacuuu uuacagcaac      120

aaagaaauau uucuccgcga guuaauauca aacgcuucag augcacuuga uaaaauaaga      180

uacgagagcc uaacagaccc uaguaaacua gauagcggua aagaacuaaa aauagacaua      240

auacccaacc cgcaagaaag aacacuuaca cuugucgaua cuggaauagg aaugacaaaa      300

gcagaucuaa uaaauaacuu aggaacaaua gcaaaaucag ggacgaaagc guuuauggaa      360

gcauuacaag caggagcaga uauuaguaug auaggacaau uuggaguagg auucuacagu      420

gcuuaucuug uagcagaaaa aguaguagua auaacaaaac acaaugacga cgaacaauau      480

gcuugggaau cuucagccgg agggucauuc acgguuagag cagaccacgg agaaccaaua      540

ggaagaggca cuaagguaau acuacauuua aaggaagauc agacagaaua ccuugaagaa      600

cgaagaguaa aagaaguagu aaaaaaacau ucacaauuua uaggauaccc cauaacauua      660

uaccuggaaa aagaaagaga aaaagaaaua ucugacgacg aagccgaaga agaaaaagga      720

gaaaaagaag aagaagacaa agaugaugaa gaaaaaccga aaaucgaaga cguaggauca      780

gacgaagaag acgacucagg aaaagacaaa aaaaaaaaaa caaaaaaaau aaaagaaaaa      840

uacauagauc aagaagaauu gaacaaaaca aaaccaauau ggacaagaaa uccagaugau      900

auaacacaag aagaauaugg agaauucuac aaaagucuua caaaugacug ggaagaccau      960

cuagcaguca aacauuuuuc aguagaagga caacuagaau ucagagcguu auuauuuaua     1020

ccaagaagag cgccauucga ccuauuugaa aacaaaaaaa aaaaaaacaa uauaaaacua     1080

uacguaagaa gagucuucau aauggacucg ugcgaugaau uaauaccaga auacuuaaau     1140

uucauaagag gaguagucga uuccgaagac uuaccacuaa auauaucucg agaaauguua     1200

caacaaucca aaauacuaaa agugauaaga aaaaauaucg uaaaaaaaug ucuugaacua     1260

uuuucggaac uugcggaaga caaggaaaau uauaaaaaau uuuaugaagc guucaguaaa     1320

aacuuaaagc uaggcauaca ugaagacucc acaaauagaa gaagacuaag cgaacuauua     1380

agauaccaua caucacaauc aggagacgaa augacaucuc uaagugaaua ugugagcagg     1440

augaaagaaa cccaaaaauc aauauacuac auaacaggag aaucgaaaga acagguagca     1500

aauucagcau ucgucgaacg uguacgcaaa agaggauuug aaguaguaua caugacugag     1560

ccaauagacg aauauugugu acaacaacua aaagaauucg acggaaaaag ucuagucagu     1620

guaacaaaag aaggacuaga acuaccagaa gaugaagaag aaaaaaaaaa aauggaagaa     1680

agcaaagcaa aguucgaaaa uuuaugcaaa uuaaugaaag aaauacuaga uaaaaaaguc     1740

gaaaaaguua caauuucaaa uagacuaguc ucaucaccau gcugcauagu cacaagcaca     1800

uacggaugga ccgccaauau ggaaagaaua augaaggcac aagcauuaag agauaacagc     1860

acgaugggau acaugauggc aaaaaaacau cuugaaauaa auccagacca cccaauaguc     1920

gaaacacuaa gacagaaagc agaagcagau aaaaacgaca aagcuguaaa agaccucgug     1980

guccugcucu ucgaaacagc auuacugagu ucaggauucu cgcuggaaga cccacagacu     2040

cauucaaaua gaauuuacag aaugauaaaa cuaggauuag gaaucgauga agacgaagug     2100

gcagcagaag aaccaaacgc cgcgguccca gacgaaauac cuccauuaga aggagacgag     2160

gaugcaagcc gaauggaaga aguagauuaa ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  2006
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt6)

<400>  2006
gggagaaagc uuaccaugcg agcuuuaugg guacuaggcu uauguugcgu auuacuuaca       60

uucggaucag uacgugcaga cgaugaagua gauguagaug guacaguaga agaagauuua      120

ggcaaaucaa gagaaggaag uaggacagac gaugagguag uacaaagaga agaagaagca      180

auucaacuag acggacuuaa cgcaucucaa auaagagaau uacgagaaaa aucagaaaaa      240

uuugcauucc aggcagaagu aaauagaaug augaaacuaa ucauaaauag ucucuauaaa      300

aacaaagaaa uauucuuacg agaacuaaua ucaaaugcaa gugaugcuuu agacaaaaua      360

cgacuuauca gucuaacaga ugaaaaugca cucaguggca augaagaacu aacaguuaaa      420

auaaaaugcg auaaagagaa aaauuuacua cauguuacag acaccggugu aggaaugaca      480

agagaagaau uaguuaaaaa uuuaggaaca auagcaaaaa guggaacaag ugaauuucua      540

aauaaaauga cugaagcuca ggaagaugga caaagcacuu cagaacuaau uggacaauuc      600

ggaguaggau ucuacucagc auuccuugua gcugauaaag uaaucguaac uagcaaacac      660

aauaacgaca cacaacauau augggaauca gauucaaacg aauuuagcgu aauugcagau      720

ccaagaggaa auacacuagg aagagggacc acaauaacau uaguacuaaa agaggaagca      780

agcgacuacu uagaacucga uacgauuaaa aauuuaguaa agaaauacuc acaguuuaua      840

aauuucccaa uauacgucug gaguaguaaa acagaaacag uagaagaacc aauggaggaa      900

gaagaagcag ccaaagaaga aaaagaagaa ucggacgacg aagcugcugu cgaagaagaa      960

gaagaagaaa agaaaccaaa aacaaagaaa guagagaaaa cuguuuggga uugggaauua     1020

augaacgaua ucaaaccaau auggcaaaga cccucaaaag aagucgaaga agacgaauau     1080

aaagccuuuu acaagucauu uuccaaagaa ucggaugacc caauggcaua uauucacuuu     1140

acagcagagg gagaagucac auuuaaaucu auacuuuuug ucccaacaag ugcaccgaga     1200

ggauuauuug augaauacgg uucaaagaaa ucagacuaua uaaaauuaua uguaagaaga     1260

guguucauaa cagacgacuu ucacgauaug augccgaaau acuuaaacuu uguuaaagga     1320

gucguugaca gcgaugaccu accacucaac guaaguagag aaacacuaca acaacauaaa     1380

cuauugaaag uuauaagaaa gaaacucgua agaaaaacuu uagacaugau uaagaaaaua     1440

gcagacgaca aauauaacga uacauuuugg aaagaguucg guacaaauau aaaacuagga     1500

guaauagaag accacaguaa uagaacccga uuagccaaau uacucagguu ccaaucaucg     1560

caucacccaa cagacaucac gagcuuagau caauauguag aaagaaugaa agaaaaacaa     1620

gauaaaauau acuuuauggc gggaucauca agaaaagaag ccgaaucuuc uccauucguu     1680

gaacgacuau uaaagaaagg auaugaagua auauaccuaa cagaaccugu agaugaauau     1740

uguauacaag cacuaccaga auuugauggc aaacgcuucc aaaauguagc aaaagaaggc     1800

guuaaauuug augaaagcga aaagacaaaa gaaaguagag aagcgguuga aaaagaguuc     1860

gaaccauuau uaaauuggau gaaagacaaa gcacuaaaag auaaaauaga aaaagcugua     1920

guaucucaaa gauuaaccga auccccgugc gcacucguag ccagucaaua uggcugguca     1980

gguaacaugg aaagaauaau gaaagcucaa gcauaucaaa caggaaaaga uauaaguacg     2040

aacuauuacg caucucaaaa gaaaacauuc gaaauaaauc caagacaccc acugauaaga     2100

gauauguuaa ggcgaauaaa agaagaugaa gacgacaaaa caguucuaga cuuagcuguc     2160

guacuauucg aaacagcaac auuaagaagc ggauacuuac uaccagacac aaaagcauau     2220

ggagauagga uagaacggau guuacgacua agucucaaca uagauccaga ugccaaaguu     2280

gaagaagaac cagaagagga accagaagag accgcagaag acacaacaga agacacagaa     2340

caggacgaag acgaagaaau ggacguagga acugacgaag aagaagaaac agcaaaagaa     2400

ucuacagcag aaaaagacga gcuguaagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  2007
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt6)

<400>  2007
gggagaaagc uuaccauggc acgagaauua agagcucuuu uacuaugggg uagacgacug       60

agaccauuau uaagggcgcc agcccucgca gcaguaccag gaggaaaacc aauacucugc      120

ccaagaagaa caaccgcaca auuaggccca agaagaaauc cagcaugguc auuacaagcu      180

ggaagacuau uuuccaccca aacagcagaa gauaaagaag aacccuuaca uucaauaaua      240

ucaagcacag aaucagucca aggaucaaca ucaaaacaug aauuucaagc agaaacaaag      300

aaacuauuag auauuguugc uagaagccuu uauucugaaa aagaaguauu uauaagagaa      360

cuaauuagua acgcuagcga cgccuuagaa aagcuaagac acaaguuagu aagugaugga      420

caagcauuac cagaaaugga aauacaccug caaaccaaug cagaaaaagg aacaauaacc      480

auacaagaua ccggcauagg aaugacacaa gaagaauuag uaaguaaccu uggaacaaua      540

gcuagaagcg gaucaaaagc auuccucgac gcacuacaaa accaagcaga agcaucaucc      600

aaaauaauug gacaauuugg cguaggauuc uauagugccu uuaugguagc agaucguguc      660

gaagucuauu cacgaucagc agcaccagga ucacuagggu aucaaugguu aucagacgga      720

uccgguguau ucgaaauugc cgaagccucg ggcguaagaa cggguacuaa aauaauaaua      780

cauuuaaaau cagauugcaa agaauucucu ucagaagcac gaguccgaga uguaguaacg      840

aaauauucaa acuuuguuag uuuucccuua uauuuaaaug gucguagaau gaauaccuua      900

caagcaauau ggaugaugga uccaaaagau guuagagaau ggcaacauga agaauuuuau      960

agauauguug cucaagcuca ugacaaaccc cgauauacuu uacacuacaa aacagacgca     1020

ccauuaaaua ucaggaguau auuuuaugug ccagauauga aacccucgau guuugauguc     1080

aguagagaau uaggaagcag uguggcucua uauucuagaa aaguacucau acaaaccaaa     1140

gcaacggaua uauuaccaaa auggcucaga uuuauaagag gaguuguuga uucagaagac     1200

auacccuuaa aucuuaguag agaacuacuu caagaaucag cauuaauaag aaaauuaaga     1260

gacguccuuc aacaaagauu aauuaaauuc uuuauagacc aaucaaaaaa agaugcagaa     1320

aaauaugcaa aauucuucga agacuaugga uuauuuauga gagaaggaau aguaacagca     1380

acagaacaag aaguaaaaga ggauauagca aaauuauuac gguacgaauc aucagcauua     1440

ccaucaggac aacuuacauc auuauccgaa uacgccaguc gaaugagagc aggcacaaga     1500

aacauauauu accuaugugc accaaacaga caucuagcag agcacucacc uuauuacgaa     1560

gcaaugaaaa aaaaagauac agaaguucua uuuugcuuug aacaauuuga cgagcuuacc     1620

uuacuccauc uaagagaauu ugacaaaaaa aaauuaauaa guguugaaac agacauagua     1680

guugaucauu auaaagaaga aaaauuugaa gaucgaagcc cagcagcaga augccuauca     1740

gaaaaagaaa ccgaagaauu aauggccugg augcguaaug uucuaggaag cagaguuaca     1800

aacguaaaag uaacgcuaag auuagauacu cauccagcca ugguaacugu gcuagaaaug     1860

ggcgcagcca ggcacuuccu aagaaugcaa caauuagcaa aaacacaaga agaaagagca     1920

caauuacuuc aaccaacacu ugagauaaau cccagacaug cauuaaucaa aaaacuaaac     1980

caacuucgug caagcgaacc aggauuagca caacuuuuag uugaucaaau auaugaaaac     2040

gcaaugauag cagcuggacu cgucgaugau ccaagagcaa uggugggacg ccuuaaugaa     2100

uuauugguaa aagcauugga acgacauuaa ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  2008
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt6)

<400>  2008
gggagaaagc uuaccauggg aaaaauauca ucacuaccaa cacaacuauu caaaugcugc       60

uucugcgacu uccuaaaagu aaaaaugcac acaaugucau caucacaccu auucuaccua      120

gcacuaugcc uacuaacauu cacaucauca gcaacagcag gaccagaaac acuaugcggc      180

gcagaacuag uagacgcauu acaauucgua ugcggagaca gaggauucua cuucaacaaa      240

ccaacaggau acggaucauc aucaagaaga gcaccacaaa caggcauagu agacgaaugc      300

ugcuuccgau caugcgaccu aagaagacua gaaauguacu gcgcaccacu aaaaccagca      360

aaaucagcaa gaucaguaag agcacaaaga cacacagaca ugcccaaaac acaaaaagaa      420

guacaccuaa aaaacgcauc cagaggauca gcaggaaaca aaaacuacag aauguaagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  2009
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt6)

<400>  2009
gggagaaagc uuaccauggg aauaccaaug ggaaaaucaa ugcuaguacu auuaacauuu       60

cuagcauuug caagcuguug cauugcagca uacagaccau cagaaacacu auguggagga      120

gaauuaguag auacauuaca auuuguaugu ggagauagag gauucuauuu cucaagacca      180

gcaucaagag uuagcagaag aaguagagga auaguagaag aaugcuguuu cagaagcugu      240

gauuuagcau uacuagaaac auauugcgca acaccagcaa aaagugaaag agauguauca      300

acaccaccaa cuguauuacc agauaacuuu ccaagauacc caguaggaaa auucuuucaa      360

uacgauacau ggaaacaaag cacacaaaga cuaagaagag gacuaccagc auuauuaaga      420

gcaagaagag gacacguucu agcaaaagaa cuagaagcau uuagagaagc aaaaagacau      480

agaccacuaa uagcauuacc aacacaagau ccagcacacg gaggagcacc accagaaaug      540

gcaucaaaca gaaaauaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  2010
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt6)

<400>  2010
gggagaaagc uuaccaugaa uuccuucuca acaucagccu ucggaccagu agccuucuca       60

cuaggacuac uacuaguacu acccgcagca uucccagcac cagucccacc aggagaagac      120

ucaaaagacg uagcagcacc acacagacaa ccauuaacau caucagaacg aauagacaaa      180

caaauaagau acauauuaga cggaauauca gcacuaagaa aagaaacaug caacaaauca      240

aacaugugcg aaucaucaaa agaagcccua gcagaaaaca accuuaaucu accaaaaaug      300

gcagaaaaag acggaugcuu ccaaucagga uucaacgaag aaacaugccu aguaaaaaua      360

auaacaggac uacuagaauu cgaaguauac cucgaauacc uacaaaacag auucgaaucc      420

ucagaagaac aagcccgagc aguccaaaug ucaacaaaag uacuaauaca auucuuacaa      480

aaaaaagcaa aaaaucuaga cgcaauaaca acaccagacc caacaacaaa cgccuccuua      540

cuaacaaaac uacaagcaca aaaccaaugg uuacaagaca ugacaacaca ccucauacua      600

agaucauuca aagaauuccu acaauccuca cuaagagcac uuagacaaau guaaggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  2011
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt6)

<400>  2011
gggagaaagc uuaccaugcc acuacugugg uuaagagguu uccuauuagc aagcugcugg       60

auaauaguaa gaagcagucc aacaccaggg agcgaaggac acagugcggc accagacugc      120

ccaucaugug cgcuagcagc auuaccaaaa gacguuccaa auagucaacc agaaaugguu      180

gaagcaguaa aaaaacauau auuaaauaug cuacaucuaa aaaaaagacc agauguaaca      240

caaccaguac cgaaagcagc auuauuaaau gcaauacgaa aauuacaugu cggaaaagua      300

ggagaaaacg gauauguaga aauagaagac gacauuggaa gaagagcaga aaugaacgaa      360

uuaauggaac aaacaaguga aauuauaacg uuugcagaau caggaacagc cagaaaaaca      420

cuacacuuug aaauaucaaa agaaggcuca gaccuaucag uuguagaaag agcggaagua      480

ugguuauuuc uaaaaguacc uaaagcaaac agaacaagaa caaaaguaac aauuagacua      540

uuucaacaac aaaaacaccc acaaggaagu cuagauacag gagaagaagc agaagaagua      600

ggauuaaaag gagaaaggag ugaauuacua uuaagugaaa aaguaguaga cgcaagaaaa      660

ucaacauggc acguauuucc aguaucauca agcauacaac gacuacuaga ccaaggaaaa      720

uccucauuag auguaagaau cgcaugcgaa caaugucaag aaaguggugc aucauuagua      780

cuauuaggaa aaaaaaaaaa aaaagaagaa gaaggagaag gaaaaaaaaa aggaggagga      840

gaaggaggug caggagcaga cgaagaaaaa gaacaaagcc auagaccauu cuuaauguua      900

caagcaagac aaagugaaga ccauccucau aggagaagaa gaagaggacu ugaaugcgac      960

ggaaaaguaa auauauguug uaaaaaacaa uucuuuguaa gcuuuaaaga uauaggaugg     1020

aacgauugga uaauagcucc aaguggauau cacgcaaauu acugcgaagg agaaugccca     1080

ucacacauag cgggaacaag cggaagcuca cuaucauucc auagcacagu aauaaaccau     1140

uacagaauga gaggacauag uccauucgca aacuuaaaau caugcugugu cccaacaaaa     1200

cuaagaccaa uguccauguu auauuaugau gacggucaaa auauaauaaa aaaagauaua     1260

caaaacauga uaguagaaga auguggcugu agcuaaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  2012
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt6)

<400>  2012
gggagaaagc uuaccaugga uggauuaccc gggagggcac uaggugcagc uugccuauua       60

cuacuagcag caggauggcu aggaccagaa gcauggggaa gcccgacacc accuccuaca      120

ccagcagcac caccaccacc uccuccacca ggaucaccag gaggaaguca agacacaugu      180

acaucaugcg gaggauuccg aagaccagaa gaacuaggaa gaguagaugg agauuuucua      240

gaagcaguua aacgacauau acuaucuaga cuacaaaugc gaggaagacc aaauauaaca      300

cacgcaguuc caaaagcagc aaugguaaca gcacuuagaa aauuacaugc agguaaagua      360

cgugaagaug gaagaguaga aauaccacau cuagacgguc acgcuucacc aggagcugac      420

ggucaagaaa gaguaucaga aaucaucagc uuugccgaaa cugauggacu agcaucauca      480

cgaguuagau uauauuuuuu uauuaguaau gaaggaaauc aaaauuuauu cguuguccaa      540

gcuucauuau ggcuuuauuu aaaauuacua ccuuauguau uagaaaaagg aucaagaaga      600

aaaguaagag uuaaagucua uuuccaagaa caaggucaug gagauagaug gaauauggua      660

gaaaaaagag uagaccuaaa aagaucagga uggcacacuu ucccauuaac agaagcaaua      720

caagcauuau ucgaaagagg agaaagaaga cuaaauuuag acguucaaug ugacucaugu      780

caagaauuag caguaguacc aguuuuuguc gauccaggag aagaaaguca uagaccuuuu      840

guaguaguac aagcgagauu aggagauuca agacacagaa uaaggaaaag aggauuagaa      900

ugugacggga gaacaaacuu auguuguaga caacaauuuu uuauagauuu ucgacuaaua      960

ggauggaaug auuggauaau agcaccuaca ggauauuaug gaaauuauug ugaaggaagu     1020

uguccagcau auuuagcagg aguaccagga ucagcaagca guuuucauac agcaguaguu     1080

aaucaauaua gaaugagagg acuaaauccu ggaacgguaa auucguguug cauuccuaca     1140

aaacuaucaa caaugagcau guuauacuuc gaugacgaau auaauauagu uaaaagagac     1200

guaccaaaca ugauuguaga agaaugugga ugugcuugag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  2013
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt6)

<400>  2013
gggagaaagc uuaccauggc ucucagagua cuacuacuaa cugcacuaac uuuaugccac       60

ggcuucaacu uagauaccga aaacgccaug acuuuucaag aaaaugcaag agguuucgga      120

caaucuguag uacaacuaca aggcucaagg guaguuguag gcgccccuca agaaaucgua      180

gccgcuaauc agcgagguuc ucuuuaucaa ugugauuauu caacuggauc cugugaaccc      240

auccgauuac aaguaccugu agaagcugua aauaugucac uuggacuaag ucucgcugca      300

acaacaucac ccccgcaacu acucgcaugu ggcccaaccg uacaucagac auguucugaa      360

aacacauacg uaaaaggauu auguuuccua uuuggcagua acuuacgaca acaaccacaa      420

aaauucccag aagccuuaag aggauguccu caagaagaua gcgauauugc auuccucaua      480

gauggaucug guuccauuau accucaugau uuccggcgaa ugaaagaauu uguuucaaca      540

gucauggaac aacuaaagaa aucaaaaaca uuauuuuccu uaaugcaaua uagugaagag      600

uuccgaauac auuuuaccuu caaagaauuu caaaauaacc caaacccgcg aagucucgua      660

aaacccauua cccaacuucu agguagaacu cacacagcaa cagguauuag aaaaguuguu      720

cgagaguuau uuaauauuac aaacggagca cguaaaaacg cuuucaaaau ccuaguugua      780

auaacagacg gagaaaaauu uggugaccca cuagguuaug aagauguuau cccagaggcu      840

gacagagaag gagucauuag auaugucaua ggaguaggag augcauuccg cagugagaaa      900

aguagacagg aacuuaacac gauagccucu aaacccccaa gggaucacgu cuuccaagua      960

aacaacuuug aggcuuuaaa aaccauacaa aaccaauugc gugagaaaau uuuugcuaua     1020

gaagggacac aaacuggauc cucaucuuca uuugaacaug aaaugucuca agaaggauuu     1080

ucagcagcca ucacaucaaa cggaccuuua cuaucaaccg uuggcuccua ugauugggcu     1140

ggaggagucu uccuuuauac uucuaaagaa aaauccacuu uuauaaauau gacccggguu     1200

gauagcgaca ugaaugacgc cuauuugggu uaugcagcug cuauaauacu acgaaaucgu     1260

guccaaaguu uaguccuagg agcucccaga uaucagcaua uugguuuagu ugcgauguuu     1320

agacaaaaca cagguaugug ggaaucaaau gcaaauguua aaggaacaca aauuggggca     1380

uauuucggcg cuucccuaug uucaguagac gucgauucaa auggauccac ggauuuaguu     1440

cucauaggug caccacacua uuaugaacaa acccgaggug gccaagucuc cguaugcccc     1500

cuaccacgcg gccgugcacg uuggcagugc gacgcuguac uuuaugguga acaaggacaa     1560

ccuuggggac guuuuggagc agcccuaacu guacuuggag acguuaaugg cgacaaauua     1620

acggauguug cgaucggggc accaggcgaa gaagauaaua gaggagccgu auacuuauuu     1680

cauggcacaa gcggcucagg aauaucaccu ucacauaguc aaagaauagc aggaucaaaa     1740

cuaucuccaa gauuacaaua cuuugggcaa agucuaagcg gcggacaaga ccuuacaaug     1800

gauggauuag uagaucuaac cguuggagca caaggacaug uauuauuauu aagaucccaa     1860

ccuguucuua gagucaaagc uauuauggaa uuuaacccua gagaaguagc ucgcaauguu     1920

uuugaaugua augaucaggu uguuaaaggu aaagaagcag gagaaguccg uguuugucuu     1980

cacguacaga aaucaacuag ggauagacua agagaaggac aaauacaaag uguuguuaca     2040

uaugauuuag cacuagacuc uggucgacca cauucaagag caguuuucaa cgagacuaaa     2100

aacucaacac gaagacaaac ccagguauua gguuuaacac aaacuugcga aacacuuaaa     2160

cuacaauuac cuaauugcau agaagaucca guuucaccaa uaguccuacg auuaaacuuc     2220

ucauuaguug gcaccccacu guccgcuuuc ggaaaccuac gucccguccu cgcagaagac     2280

gcacaaagac uauuuacagc uuuauucccu uuugaaaaga auugcggcaa ugauaauaua     2340

ugucaagacg aucuuucaau uacuuuuagu uuuaugucac uagauugccu aguaguagga     2400

ggaccaagag aauuuaaugu aacaguuaca guacgcaacg acggagaaga cucuuaucga     2460

acacaaguua cauuuuucuu uccauuagac uuaaguuacc gaaaaguauc aacccuucaa     2520

aaucaacgau cacaaagauc auggagguua gccugcgaau cggcaucauc cacugaagua     2580

ucuggugcac ucaaaaguac uucauguucc auuaaucauc cuauauuucc ugaaaauucc     2640

gaaguaaccu uuaacauaac auuugauguu gauucaaaag ccucucucgg uaauaaauua     2700

cuacuuaaag caaacgugac auccgaaaau aacaugccaa gaacuaauaa aacggaauuu     2760

caauuagaau uaccuguuaa guacgcaguc uacaugguug ugacaaguca uggcguuucc     2820

acaaaauauc uuaacuuuac agcaagugaa aacacaucaa ggguuaugca acaucaauau     2880

caagucagua accuugguca acgaagccua ccaaucucau uggucuuucu cgucccagua     2940

agacuaaauc aaaccguaau augggaucga ccgcaaguua cuuucaguga aaacuuaagu     3000

ucuacaugcc acacaaaaga aagacuucca ucucacucug acuuucuagc ugaacuacga     3060

aaagcucccg uuguaaacug uucuauagca guuugucaac guauacaaug ugauauucca     3120

uucuuuggaa uacaagaaga guucaaugcu acauuaaaag guaauuuauc guuugauugg     3180

uacauuaaaa cuagccauaa ucauuuauua auaguuucua cugcagaaau ccuguuuaau     3240

gauuccguau ucacucuauu acccggacaa ggagcauuug uaagauccca aaccgaaaca     3300

aaaguagaac cuuuugaagu ccccaacccu cuuccuuuaa ucguuggauc aagcguuggc     3360

ggacuauuac uuuuagccuu aauaacggcg gcauuauaua aauuaggauu cuucaaacgc     3420

caauauaaag auaugauguc ugaaggugga ccuccuggag cagaaccaca auaaggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  2014
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt6)

<400>  2014
gggagaaagc uuaccauguu uucacuaaaa acauuaccuu uccuacuucu acuacacgua       60

caaauaucaa aagcauuucc agucucauca aaagaaaaaa acacaaaaac aguacaagau      120

uaucucgaaa aauuuuacca auuaccauca aaucaauauc aaucaacacg aaaaaaugga      180

acaaacguaa uaguugaaaa auuaaaagaa augcaaagau ucuuuggacu caaugucaca      240

ggcaaaccua acgaagaaac acuagacaug augaaaaaac caagaugcgg aguaccagac      300

ucaggaggau ucauguuaac cccaggcaac ccuaaauggg aaagaacaaa ucuaacauac      360

agaauacgaa acuauacacc acaacuaucc gaagcagaag ucgaaagagc aauaaaagac      420

gcuuuugaac uuuggucagu agccucccca cuaauauuca cacgaauauc acaaggagaa      480

gccgacauca acauagcauu uuaucaacga gaccacggag acaauucccc cuucgacgga      540

ccaaauggaa uacuagcaca cgcauuccaa ccuggacaag gaauaggagg agaugcacau      600

uucgacgcag aagaaacaug gacaaacaca ucagcaaacu acaaccuauu cuuagucgca      660

gcacacgaau ucggacauuc ucuaggacua gcccauucau cugaccccgg cgcacuaaug      720

uauccaaacu acgcauuuag agaaacaucc aacuacuccc uaccccaaga cgauauagau      780

gguauccaag caauauacgg acuauccuca aauccaauac aaccaacagg ccccucuaca      840

ccaaaaccau gcgacccauc ccuuacauuc gacgcaauaa caacccuccg aggagaaaua      900

uuauucuuua aagacagaua cuucuggaga agacacccuc aacuccaacg aguugaaaug      960

aacuucauau cuuuauuuug gccaucucua ccaacaggga uccaagcagc uuacgaagau     1020

uuugaucgcg acuuaauauu uuuauucaaa ggaaaucaau acugggcauu aucaggauau     1080

gauauacuac aaggauaccc caaagacaua ucaaauuaug gauuccccuc cucaguccaa     1140

gccaucgacg cugcaguauu cuaccgauca aaaaccuacu ucuuuguaaa ugaccaauuu     1200

uggagauacg auaaucaacg ucaauucaug gaaccugguu auccaaaauc aauaucuggc     1260

gcauuucccg gaauagaaag caaaguagac gcagucuuuc aacaagaaca cuucuuccac     1320

guauuuagcg gaccaagaua cuacgccuuu gacuuaauag cacaaagagu aacacgaguu     1380

gcaagaggaa acaaauggcu aaacuguaga uacggauaag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2015
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt6)

<400>  2015
gggagaaagc uuaccaugag ucuauggcaa ccauuaguau uaguuuuacu uguacucggu       60

uguugcuucg cugcaccuag acaacgucaa ucaacccucg ugcucuuucc aggagaucuu      120

cgaacuaauu uaacagauag acaauuagca gaagaauauu uauauaggua uggcuauaca      180

cgaguagcug aaaugcgagg agaaaguaaa agccuaggac cugccuuauu acuacuacaa      240

aaacaacuau cauuaccaga aacuggagaa uuagacuccg cuacucuaaa agcaaugcgc      300

accccacguu gcggaguacc agauuuagga cgauuucaaa cauuugaagg agauuuaaaa      360

uggcaucauc acaauauaac auacuggauu caaaacuaca gugaagauuu acccagggca      420

guaauagacg augcauuugc aagggcauuu gcauuauggu cagcuguuac uccacucacu      480

uucacuagag uuuacaguag agaugcagau aucguaauac aauuuggagu agcagaacac      540

ggcgacggau acccauucga cgguaaagau ggacuacuag cucaugccuu cccaccaggu      600

ccagguauac aaggagacgc acauuuugau gaugaugaau uauggaguuu aggcaaggga      660

guugucguac caacucgauu uggaaaugcu gauggugcag cuugccauuu ucccuuuauu      720

uucgaaggga gaucguauuc agcuugcaca acagacggaa gauccgaugg ucuaccaugg      780

ugcucuacaa cagcuaacua ugacacagac gauagauucg gauucugccc auccgaacga      840

uuauauacuc aagauggaaa ugcagacggu aaaccauguc aauucccauu uauauuccaa      900

ggacaaucau auagcgcuug cacaacagau ggaagaagcg auggauacag auggugcgca      960

acaacagcua acuaugaucg agacaaacua uuuggauuuu guccaacacg ugcugauucc     1020

acaguaaugg gaggaaauuc ugcuggugaa cuauguguau ucccauuuac auuccuuggu     1080

aaagaauacu cuacauguac aagcgaaggc agaggcgacg gaagacuuug gugugcuaca     1140

acaucuaauu uugauaguga uaaaaaaugg ggauucuguc cagaccaagg auacucauua     1200

uuucuaguag cugcacauga auuuggacau gccuuaggau uagaucauag uucuguacca     1260

gaagcucuga uguauccuau guaccgauuc acugaaggac caccacucca uaaagacgau     1320

guuaauggaa uaagacauuu guacggaccc aggccagaac cagaaccaag accaccaaca     1380

acaacaacuc cucaaccgac agcaccacca acaguuuguc caacaggacc ccccacagua     1440

cauccaucag aaagaccuac agcaggacca acagguccgc caucagccgg accaacugga     1500

ccuccaacag caggccccuc cacagcaaca acaguaccau uaucaccagu agaugaugca     1560

ugcaauguaa auauauuuga ugcuauagca gagauaggca aucaacuaua ucucuuuaaa     1620

gacggaaaau auuggagauu cucagagggc agaggaucaa gaccccaagg accauuuuua     1680

auugcagaua aauggccagc uuuaccaagg aaauuagauu cagucuuuga agagcgccuc     1740

ucaaaaaaau uauuuuuuuu cucaggaaga caagucuggg uuuauaccgg agcauccgua     1800

uuaggaccaa gaagauuaga caaauuaggu uuaggugcug augucgcaca aguuacagga     1860

gcuuuacgaa gcggucgagg aaaaaugcua cuguucucug guagaagacu auggagauuu     1920

gacguaaaag cgcaaauggu agacccucga agcgcuagug aaguagauag aauguucccu     1980

gguguaccuc uugacaccca ugacguuuuu caauacagag aaaaagcaua uuuuugccaa     2040

gaucgcuucu acuggcgagu uaguucacgu agcgaacuaa aucaaguaga ccaaguugga     2100

uaugucacau acgauauacu acaaugucca gaagacuaag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  2016
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt6)

<400>  2016
gggagaaagc uuaccaugca cccaggugua cuugcagccu ucuuauuuuu aucauggacu       60

cacuguagag cacucccacu accaucagga ggagacgaag augauuuauc agaagaagac      120

cuccaauucg cagaaagaua ucuaagaucu uacuaucacc caacaaacuu agcagguaua      180

cuaaaagaaa acgcagcauc aucaaugaca gaaagacuaa gagaaaugca aucauucuuu      240

ggauuagaag uaacaggaaa acuagaugau aauacacuag acguaaugaa aaaacccaga      300

ugcggaguac cugauguagg agaauacaac guauucccaa gaacacuaaa auggucaaaa      360

augaaucuaa cauacagaau cguaaacuau accccagaca ugacacauag ugaaguagaa      420

aaagcauuca aaaaagcauu caaaguaugg ucagacguaa caccauuaaa cuucaccaga      480

cuucacgaug gaauagcaga cauuaugauu ucauuuggca uaaaagaaca uggcgacuuc      540

uacccauucg acgguccaag cgguuuacua gcccaugcau ucccaccugg accuaacuau      600

ggcggagacg cacacuuuga cgaugacgaa acauggacca guucaaguaa aggauacaau      660

cuauuuuugg uagcugccca cgaauucggc cacucacuag gacuagacca uucaaaagac      720

ccuggugcau uaauguuccc aauauauacc uauacaggaa aaucacauuu cauguuacca      780

gaugaugaug uacaaggcau ccaaucauua uacggcccag gagacgaaga uccaaaccca      840

aaacacccaa aaacaccaga caaaugcgac ccuucacuau cucuagacgc aauaacuucu      900

uuaagaggag aaacaaugau auucaaagau cgauucuucu ggagacuuca cccacaacaa      960

guagaugcag aacuauucuu aacaaaaucu uucuggccag aacuaccaaa ccguaucgac     1020

gcagcauaug aacacccauc acaugacuua auauuuauau uuagaggacg aaaauuuugg     1080

gcauuaaacg gauaugauau auuagaagga uacccuaaaa aaauaucaga acucggauua     1140

ccaaaagaag uuaaaaaaau aucggcagcu guacacuucg aagacacagg caaaacccua     1200

uuauuuucag gaaaccaagu auggcgauau gacgacacaa aucauauaau ggauaaagau     1260

uacccaagau uaauagaaga agauuuccca ggaauaggug acaaaguaga cgcaguauac     1320

gaaaaaaaug guuacauaua uuuuuuuaac ggacccauac aauucgaaua cucaauaugg     1380

ucaaacagaa uaguacgagu caugccagca aauucgauac uuuggugcua aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2017
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt6)

<400>  2017
gggagaaagc uuaccaugga aacaccaaac acaacagaag acuacgauac aacaacugaa       60

uucgacuacg gagacgcaac accaugucaa aaagucaacg aacgagcauu cggagcacaa      120

uuacuaccuc cacuauacuc auuaguauuu guaauaggcu uagucggaaa cauacuagua      180

guacuaguuu uaguucaaua caaaagacua aaaaacauga caucuauaua cuuacuaaac      240

uuagcaauau cagaucuucu auucuuauuc acccuuccau ucuggauaga cuacaaauua      300

aaagacgacu ggguauucgg cgacgcaaug ugcaaaauau uauccggauu cuauuacaca      360

ggacuauacu cagaaauauu uuucauaaua cuccuaacaa uagacagaua ccuagcaaua      420

guucacgcag uauucgcuuu aagagcaaga accguaacau ucggaguuau aacaucaauu      480

auaaucuggg cacuagccau acuagccuca augccaggac uauacuucuc uaaaacucaa      540

ugggaauuca cacaccauac auguucacuc cacuuucccc augaauccuu aagagaaugg      600

aaacucuucc aagcacuaaa auuaaacuua uucggacuag uauuaccacu acuaguaaug      660

auaauaugcu acacaggaau uauaaaaauc cuacuuagaa gaccaaacga aaaaaaauca      720

aaagcaguca gacuaauauu cgucauaaug auaaucuuuu uuuuauucug gacaccuuac      780

aaucucacua ucuuaauauc aguuuuccaa gacuuccuau ucacacacga augugaacaa      840

ucaagacacu uagacuuagc aguacaaguc acugaaguaa uagcauacac acacugcugc      900

guaaacccag uaaucuacgc auucguagga gaaagauuua gaaaauaccu aagacaacua      960

uuccacagaa gaguugcugu acaccuagua aaaugguuac ccuucuuauc agucgaucgu     1020

uuagaaagag ucucaucaac aucacccuca acaggugaac acgaacuauc agccggauuu     1080

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  2018
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt6)

<400>  2018
gggagaaagc uuaccaugag aacauuagca ugcuuauuac uauuaggaug uggauacuua       60

gcacacguau uagcggaaga agcagaaaua ccaagagaag uaauagaaag acuagcacga      120

ucacaaauac acucaauaag ggaccuacaa agauuacuag aaauagacuc aguaggaagc      180

gaagacucac uagacacauc auuaagagca cacggaguac acgcaacaaa acacguacca      240

gaaaaaagac cacuaccaau aagaagaaaa agaagcauag aagaagcagu accagcagua      300

ugcaaaacaa gaacaguaau auaugaaaua ccacgaucac aaguagaccc aacaucagca      360

aacuucuuaa uauggccacc augcguagaa gugaaaagau gcacaggcug cugcaacaca      420

ucgucaguaa aaugccaacc aagcagagua caccacagau caguaaaagu agcuaaagua      480

gaauacguaa gaaaaaaacc aaaacuaaaa gaaguacaag uaagacuaga agaacaccua      540

gaaugcgcau gcgcaacaac aagccuaaac ccagacuacc gagaagaaga uacaggaaga      600

ccgcgagaaa guggaaaaaa acgaaaaaga aaaagacuaa aaccaaccua aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  2019
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt6)

<400>  2019
gggagaaagc uuaccaugaa uagaugcugg gcacuauucu uaagcuuaug uugcuacuua       60

agacuaguau cagcagaagg agauccaaua ccagaagaau uauacgaaau gcuaagcgac      120

cacucaauca gaagcuuuga cgauuuacaa agacuacuac auggagaucc aggagaagaa      180

gacggagcag aacuagacuu aaauaugaca agaucacacu caggaggaga auuagaauca      240

cuagcaagag gaagaagaag ucuaggauca cuaacaauag cggaaccagc aaugauagca      300

gaauguaaaa cacgaacaga aguauucgaa auaucaagaa gauuaauaga cagaacaaau      360

gcaaacuucc uaguauggcc accaugcgua gaaguacaaa gaugcucagg auguugcaau      420

aacagaaacg uacaauguag gccaacacaa guacaauuaa gaccagugca aguaagaaaa      480

auagaaauag uacguaaaaa accaauauuu aaaaaagcaa caguaacacu agaagaccau      540

cuagcaugua aaugcgaaac aguagcagcg gccagaccag uaacaagaag cccaggagga      600

agucaagaac aaagagcaaa aacaccacaa acuagaguua caauaagaac aguaagagua      660

agaagaccac caaaaggaaa acauagaaaa uucaaacaca cacaugauaa aacagcacua      720

aaagaaaccu uaggagcaug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  2020
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt6)

<400>  2020
gggagaaagc uuaccaugag cuuauucgga cuacuacucc uuacuucagc acuagcagga       60

caaagacaag gaacacaagc agaaucaaac cuaagcucaa aauuccaauu uucaucaaac      120

aaagaacaaa auggaguaca agauccacaa cacgaaagga uuauuacagu cucaacaaac      180

ggaaguauac acaguccaag auucccacau acauacccaa gaaacacagu uuuagucugg      240

cgacuaguag caguagaaga aaauguaugg auacaacuaa cauucgauga aagauucgga      300

uuagaagacc cagaagacga cauaugcaaa uaugacuuug uagaagucga agaaccaagu      360

gacgguacaa uacuaggaag auggugcgga ucaggaacag uaccaggcaa acaaauaagu      420

aaaggaaacc aaauuagaau aagauucgua ucagaugaau acuuuccauc agaaccagga      480

uucugcauac auuacaacau aguaaugcca caauucaccg aagcaguuuc accaucaguu      540

uuaccaccaa gugcccuccc auuagaccua cuaaacaacg caauaacugc auucaguacu      600

cuagaagacc uaauaagaua ccuagaacca gaaagauggc aauuagaucu cgaagaccua      660

uauagaccaa cauggcaacu auuaggcaaa gcauuuguau ucggaagaaa aucaagagua      720

guagacuuaa accuauuaac agaagaagua agacuauaca gcugcacacc aagaaacuuu      780

ucaguuucaa uaagagaaga auuaaaaaga acagauacaa ucuucuggcc aggaugucua      840

uuagucaaaa gaugcggcgg aaacugcgca ugcugccuac auaacugcaa cgaaugccaa      900

ugcguaccaa guaaaguaac aaaaaaauac cacgaaguau uacaacuaag accaaaaacu      960

ggaguaagag gucuacacaa aucacuaacu gacguagcau uagaacauca cgaagaaugu     1020

gacugcgucu gcagaggauc aacaggagga uaaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  2021
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt6)

<400>  2021
gggagaaagc uuaccaugca cagacuaaua uucguauaca cacucauaug cgcaaauuuc       60

ugcucaugua gagacacauc agcaacacca caaucagcau caauaaaagc acuaagaaac      120

gccaaccuaa gacgagacga uuuauacaga agagacgaaa caauacaagu aaaagguaac      180

ggauauguac aaucaccaag auucccaaac aguuacccaa gaaaucuacu acuaacaugg      240

agacuacacu cacaagaaaa cacaagaaua caacuaguau uugacaacca auuuggacua      300

gaagaagcug aaaacgacau auguagauau gacuucguag aaguagaaga cauaagugaa      360

acaucaacaa uaauuagagg aagauggugc ggccacaaag aaguaccacc ccgaauaaaa      420

ucaaggacaa accaaaucaa aauaacuuuc aaaucagacg acuacuuugu agcaaaacca      480

ggcuuuaaaa uauacuauag cuuacuagaa gacuuccaac cagcagccgc aagugaaaca      540

aacugggaaa gcguaacauc aagcaucuca ggaguaagcu auaacucacc aucaguaaca      600

gacccaacac uaauagcaga cgcauuagac aaaaaaauag cagaauucga cacaguagaa      660

gauuuauuaa aauacuucaa cccagaauca uggcaagaag accuagaaaa uauguaccuc      720

gacacaccaa gauauagagg aagaagcuau cacgauagaa aaucaaaagu agaccuagac      780

agacuaaaug acgacgcuaa acgauauagu uguacaccaa gaaacuacag ugucaacaua      840

cgagaagaac uaaaacuagc aaacguagua uucuuuccac gaugucuacu aguacaaaga      900

uguggaggaa acugcggaug cggaacagua aauuggagau caugcaccug caacagcgga      960

aaaacaguua aaaaauacca cgaaguacua caauucgaac cuggccacau aaaacgaagg     1020

ggaagagcaa aaaccauggc acuaguagau auccaacuag aucaucacga gagaugugac     1080

uguauaugua guucaagacc accaagauaa ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  2022
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt6)

<400>  2022
gggagaaagc uuaccauggu aacacacuca aaauucccag cagcaggaau gucaagacca       60

uuagacacau cauuaagacu aaaaacauuc ucaucaaaau cagaauauca acuaguagua      120

aacgcaguaa gaaaacuaca agaaucagga uucuacuggu cagcaguaac aggaggagaa      180

gccaaccuac uccuaucagc agaaccagca ggaaccuucc uaauaagaga cucaucagac      240

caacgacacu ucuucacacu aucaguaaaa acacaauccg gaacaaaaaa ccucagaaua      300

caaugcgaag gaggaucauu cucacuacaa ucagacccac gcuccacaca accaguacca      360

agauucgacu gcguacuaaa acuaguacac cacuacaugc caccaccagg agccccauca      420

uuuccaucac caccaacaga accaucauca gaaguacccg aacaaccauc agcacaacca      480

cuccccggau caccaccaag aagagcauac uacauauacu caggaggaga aaaaauacca      540

uuaguacuau ccagaccauu aucuucaaac gucgcaacac uacaacaucu augcagaaaa      600

acaguaaacg gacacuuaga cucauacgaa aaaguaaccc aacuaccagg ccccauacga      660

gaauuccuag accaauacga cgcaccacua uaaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  2023
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt6)

<400>  2023
gggagaaagc uuaccauggu accaucagca ggacaauuag cauuauucgc auuaggaaua       60

guauuagcag caugucaagc auuagaaaau ucaacaucac cacuaucagc agauccacca      120

guagcagcag cuguaguauc acauuuuaau gacuguccag auucacauac ucaauucugu      180

uuucauggaa cauguagauu cuuaguacaa gaagacaaac cagcaugugu augucauuca      240

ggauauguag gagcaagaug ugaacaugca gauuuauuag caguagucgc agcaucacaa      300

aaaaaacaag caauaacagc auuaguagua guaucaauag uagcauuagc aguacuaauu      360

auaacaugug uacuaauaca uuguugucaa guaagaaaac auugugaaug gugcagagca      420

uuaauaugua gacaugaaaa accaucagca uuauuaaaag gaagaacagc auguugucau      480

ucagaaacag uaguauaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  2024
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt6)

<400>  2024
gggagaaagc uuaccaugcc accuagcgga cucagauuau uacccuuacu acucccacuc       60

cuauggcuac uaguacuaac uccaggaaga ccagcagcag gacuaaguac auguaaaacu      120

auagacaugg aauuaguaaa aagaaaaaga auagaagcca uacguggaca aauccuaucu      180

aaauugagac uagccucacc uccaucacaa ggagaaguac caccaggacc ccuacccgaa      240

gcaguacuag cacuauacaa cucaacaaga gauagaguag caggagaauc agcagaacca      300

gaaccagaac cagaagcaga uuauuacgca aaagaaguaa cacgcguauu aaugguagaa      360

acacauaacg aaauauauga uaaauucaaa caaucuacac acucuauaua cauguucuuu      420

aauacaucag aacucagaga agccguaccc gaaccaguau uauuaucaag agcagaacua      480

agacuucuaa gacuaaaacu caaaguugaa caacacguag aacuauacca aaaauacuca      540

aacaauucuu ggagauauuu aucuaacaga cuacuagccc ccucagacuc cccugaaugg      600

cuaucauucg acguaacagg aguagucaga caaugguuau cuagaggagg agaaauagaa      660

ggauuccgac uuucagcaca cuguucuugu gauagucgcg acaacacauu acaaguagac      720

auaaacgguu ucacaacugg acguagagga gaccuugcaa caauacaugg uaugaacaga      780

ccauucuuac uacuaauggc aacaccacuc gaacgagcac aacaucuaca auccucacgc      840

cacagacgag cccuagacac aaacuacugc uucucaucaa ccgaaaaaaa uuguugcgua      900

agacaauuau acauagauuu cagaaaagac cuaggaugga aauggauaca ugaaccuaaa      960

ggauaccacg ccaauuuuug uuuaggccca uguccauaca uauggucacu agacacacaa     1020

uacucuaaag uauuagcucu auacaaccaa cacaacccag gcgcaucagc agcaccaugc     1080

uguguuccac aagcuuuaga accauuacca aucguauauu acguaggaag aaaacccaaa     1140

guagaacaau uaucaaacau gauagucaga ucauguaaau gcucuuaagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  2025
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt6)

<400>  2025
gggagaaagc uuaccaugca uuacugcgua cuaucagcau uccuaauacu acaccuagua       60

acaguagcau uaucccuauc aacuugcucc acccuagaca uggaccaauu uaugagaaaa      120

cgcauagaag caauaagagg acaaauuuua ucaaaacuca aacuaacaag cccaccagaa      180

gacuacccag aaccagaaga aguaccaccg gaagucauuu caauauacaa uucaacaaga      240

gaccuacuac aagaaaaagc aucaagaaga gcugcagcau gugaaagaga acgcagcgac      300

gaagaauacu acgcaaaaga aguauacaaa aucgacaugc cuccauucuu cccaagcgaa      360

aacgcaauac caccaacauu cuaucgacca uauuuuagaa uaguaagauu cgacgucuca      420

gccauggaaa aaaaugcuag caauuuagua aaagcagaau uuagaguuuu cagacuacaa      480

aacccaaaag cacgaguccc cgaacaacga auagaauuau accaaauacu aaaaucaaaa      540

gaccuaacau ccccaacaca aagauacaua gacucaaaag uaguuaaaac ccgagcagaa      600

ggcgaauggc uaucuuucga uguaacagac gcaguacacg aaugguuaca ccacaaagau      660

agaaaccuag guuucaaaau aucucuccac ugcccaugcu gcacauucgu accauccaac      720

aacuacauaa uaccaaacaa aucugaagaa uuagaagcaa gauucgcagg aauagacggu      780

acaucaaccu acacaucagg agaucaaaaa acaauaaaau ccacaagaaa aaaaaauuca      840

ggaaaaacac cacaccuacu acuaaugcua cuaccaagcu acagauuaga aucacaacaa      900

acaaacagac gaaaaaaaag agcacuagau gcagcauacu gcuucagaaa cguacaagac      960

aacugcuguc uccgcccacu auacauagau uucaaacgag auuuaggaug gaaauggaua     1020

cacgaaccca aaggauauaa cgccaacuuc ugcgcaggag caugcccaua uuuaugguca     1080

uccgacaccc aacacuccag aguccuaucu cucuacaaca ccauaaaccc agaagcauca     1140

gcaucacccu gcuguguauc ccaagacuua gaaccacuua caauauuaua cuacauagga     1200

aaaacaccaa aaauagaaca acuaucaaac augauaguca aauccuguaa augcucauaa     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  2026
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt6)

<400>  2026
gggagaaagc uuaccaugaa aaugcacuua caaagagcau uaguuguacu agcacuucuc       60

aacuuugcaa caguaucacu aucauuauca accugcacaa cacuagacuu uggacacaua      120

aaaaaaaaac gaguagaagc cauaagagga caaauacuau caaaacuaag acuaacauca      180

ccaccagaac caaccguaau gacacacguc ccauaccaag uauuagcccu auacaacagu      240

acaagagaac uacucgaaga aaugcacgga gaacgagaag aaggaugcac ucaagaaaau      300

acagaaucag aauacuacgc aaaagaaaua cacaaauuug auaugauaca aggauuagca      360

gaacacaaug aacuagccgu augcccaaaa ggaauaacau caaaaguauu uagauuuaac      420

guaucaucag ucgaaaaaaa ccgcacaaau cuuuucagag cagaauuucg agugcuacga      480

guaccaaauc caucaucaaa aagaaacgaa caacgcauag aacuauuuca aauccuacga      540

ccagacgaac acauagcaaa acaaagauac auaggaggca aaaaccuccc cacaagaggu      600

accgcagaau gguuaucauu cgaugucacc gacacaguac gagaaugguu acuaagaaga      660

gaaucaaacc uaggcuuaga aauaucaauc cacugcccau gccacaccuu ucaaccaaau      720

ggagacauau uagaaaacau acacgaaguu auggaaauaa aauucaaagg aguagauaau      780

gaagaugacc acggacgagg ugaucuugga agacuaaaaa aacaaaaaga ccaccacaac      840

ccacaucuaa uauuaaugau gauaccucca cacagauuag acaaccccgg acagggagga      900

caaagaaaaa aaagagcacu agauacaaac uauugcuuca gaaaccuaga agaaaacugc      960

ugcgucagac cuuuauacau agauuucaga caagaucucg gauggaaaug gguccacgaa     1020

ccaaaaggau acuaugcaaa cuuuugcucc ggccccugcc cauaucuacg aucagcagac     1080

acaacacacu caacaguacu cggacuuuau aacacucuaa accccgaagc auccgccucc     1140

ccaugcugug uuccacaaga cuuagaacca cuaacaauau uauacuaugu aggacgaaca     1200

ccaaaaguug aacaauuaag caacauggua guaaaaucau gcaaauguag cuaaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2027
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt6)

<400>  2027
gggagaaagc uuaccauggc acccguagcu gucugggcag cauuagcagu uggauuagaa       60

uuaugggcag cugcccacgc acuaccagcc caaguagcau ucacaccuua cgccccagaa      120

ccuggaucua ccugcagacu aagagaauau uacgaucaaa cagcucaaau guguuguuca      180

aaauguucac caggccaaca ugcaaaagua uucuguacaa aaacaucaga uacaguaugu      240

gauucaugcg aagauucaac uuauacacaa uuauggaauu ggguucccga augccuaucc      300

uguggaucaa gauguucauc agaucaagua gaaacccaag cauguacaag agaacaaaau      360

agaauaugua caugcagacc agguugguau ugugcacuaa gcaaacaaga aggaugcaga      420

uuaugugccc cauuaagaaa augucgacca ggcuucggag uagcacgacc uggaaccgaa      480

accucugaug uaguaugcaa accaugugca ccaggaacau uuucaaacac aacaucuuca      540

acagacauau gcagaccaca ccaaauaugu aacguuguag caauaccugg caaugccuca      600

auggaugcag uuuguacauc aacaucccca acaagaucua uggcaccagg agccguacau      660

uuaccacaac caguuaguac ucgaucacaa cauacccaac ccacacccga accauccacu      720

gcuccgucca ccucauuccu acuaccaaug ggacccucuc caccagcuga agguucuaca      780

ggagacuucg cacuaccagu uggauuaaua guaggaguaa ccgcacuagg acuucuaauc      840

auaggaguag uuaauugugu aaucaugacu caaguuaaaa aaaaaccuuu auguuuacaa      900

cgagaagcaa aaguaccaca uuuaccggca gauaaagcaa gaggaacuca aggaccagaa      960

caacaacauc uauuaauuac agcuccauca ucaucaucau caucacuaga aucaucagcu     1020

ucagcacuug aucgaagagc accuacacgu aaccaaccac aagcaccagg uguggaagcu     1080

ucaggugcag gagaagcaag agcaaguaca ggaucaucag acaguucacc aggaggucau     1140

ggaacacaag uaaauguaac uuguauagua aaugucugua gcucaucaga ucauucaucc     1200

caaugcucau cucaagccuc cucaacaaug ggagacacag auuccucucc aucagaauca     1260

ccaaaagacg aacaaguacc auuuucaaaa gaagaaugug ccuucagauc acaacuagaa     1320

acaccagaaa cuuuauuagg aucaacugaa gaaaaaccgc uacccuuagg aguaccagac     1380

gccggaauga aacccucuua aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  2028
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt6)

<400>  2028
gggagaaagc uuaccaugcc aguaaugaga uuauuuccau guuuucuaca auuauuagca       60

ggauuagcac uaccagcagu accaccacaa caaugggcau uaucagcagg aaauggaagu      120

ucagaaguag aaguaguacc auuucaagaa guguggggaa gaucauauug uagagcauua      180

gaaagauuag uagauguagu aagugaauau ccaagugaag uagaacauau guuuucacca      240

aguuguguaa guuuauuaag auguacaggu uguuguggag augaaaaccu acauugugua      300

ccaguagaaa cagcaaaugu aacaaugcaa uuauuaaaaa uaagaagugg agauagacca      360

ucauauguug aauuaacauu uagucaacau guaagaugug aaugcagacc acuaagagaa      420

aaaaugaaac cagaaagaag acgaccaaaa ggaagaggaa aaagaagaag agaaaaacaa      480

agaccaacag auugucauuu auguggagau gcaguaccaa gaagauaagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  2029
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt6)

<400>  2029
gggagaaagc uuaccaugac agauagacaa acugauacag caccgagucc gaguuaucau       60

uuauuaccag gaagaaggag aacaguagau gcagcagcau caagaggaca aggaccugaa      120

ccagcaccag gaggaggggu agaaggaguu ggagcuagag gaguagcauu aaaauuauuu      180

guccaguuau uaggaugcag uagauuugga ggagccguag uaagggcagg agaagcagaa      240

ccaucagggg cagcacgaag ugcaucaagu ggaagagaag aaccacaacc agaagaagga      300

gaagaagaag aggagaaaga agaagaaaga ggaccacaau ggcggcuggg ugcgagaaaa      360

ccaggaaguu ggacaggaga agcagcagua ugcgcagauu cagcucccgc agcgagagca      420

ccucaagcau uagcaagagc aagcggaaga ggaggaagag uagcaagaag aggagcagaa      480

gaaucagggc caccucauag cccaaguaga agggguagug caaguagagc aggaccagga      540

agagcaagcg aaacaaugaa uuuuuuauua agcuggguac auuggucauu agcgcuauua      600

cuauauuuac aucaugcaaa auggagccaa gcagcaccaa uggcagaagg aggaggucaa      660

aaccaucacg aaguaguaaa auuuauggau guuuaucaaa ggucauacug ccacccaaua      720

gaaacacuag uagauauauu ucaagaauac ccagacgaaa uagaauauau auuuaaacca      780

agcuguguac cacuaaugag auguggugga uguugcaacg augaaggacu agaaugugua      840

ccaacagaag aaucuaauau aacaaugcag auaaugagaa uaaaaccaca ccaaggacaa      900

cauauaggag aaaugaguuu uuuacaacau aauaaaugug aauguagacc aaaaaaggau      960

agagcaaggc aagaaaaaaa aucaguaaga ggcaaaggaa aaggacaaaa aaggaaaaga     1020

aaaaagagca gauauaaaag uuggagcgug uauguaggag caagaugcug ucuaaugcca     1080

uggucacuac caggaccuca uccaugugga ccauguagug aacgaagaaa acaucuauuu     1140

guacaggauc cacaaacaug uaaauguagc uguaaaaaua cagauaguag auguaaagca     1200

aggcaauuag aauuaaauga aaggacuugu agaugcgaua aaccuagaag guagggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2030
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt6)

<400>  2030
gggagaaagc uuaccaugaa cuuucuauua agcuggguac auuggucacu ugcauuauua       60

cuauauuuac aucacgcaaa auggagccaa gcagcaccaa uggcagaagg aggaggacaa      120

aaccaucacg aaguaguaaa auuuauggau guauaucaaa ggaguuacug ccauccaaua      180

gaaacacuag uggacauauu ccaagaauau ccagaugaaa uagaauauau auuuaaacca      240

agcuguguac cacuaaugag auguggagga ugcuguaacg augaaggacu agaaugcgua      300

ccaacagaag aaagcaauau aacaaugcaa auaaugagaa uaaaaccaca ccaaggacaa      360

cacauaggag aaaugucauu cuuacaacau aacaaaugcg aaugcagacc aaaaaaagau      420

cgagcaagac aagaaaaaaa aucaguaaga ggaaaaggaa aaggacaaaa aagaaaaaga      480

aaaaaaagca gauacaaaag uuggagcgua uacguaggag caagauguug cuuaaugcca      540

uggucacuac caggaccaca cccaugcgga cccuguagcg aaagaagaaa acaucuauuc      600

guacaagacc cacaaacaug caaaugcuca ugcaaaaaca cagacucaag auguaaagca      660

agacaacuag aacuaaauga aagaacaugu agaugugaca aaccaagaag auaaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  2031
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt6)

<400>  2031
gggagaaagc uuaccauguc accauuacua agaagacuau uacuagcagc auuauuacaa       60

cuagcaccag cacaagcacc aguaucacaa ccugaugcac caggacauca aagaaaagua      120

guaucaugga uagauguaua uacaagagca acaugccaac caagagaagu aguaguacca      180

cuaacaguag aauuaauggg aacaguagca aaacaauuag uacccucaug cguaacagua      240

caaagaugcg gagguuguug uccagacgau ggacuagaau guguaccuac aggucaacau      300

caaguaagaa ugcaaauauu aaugauaaga uacccaaguu cacaauuagg agaaauguca      360

uuagaagaac auucacaaug cgaauguaga ccaaaaaaaa aagacucagc aguaaaacca      420

gacagagcag caacaccaca ccauagaccu caaccaagau cuguaccagg augggacuca      480

gcaccaggag cuccaucacc agcagacaua acucauccaa caccagcacc aggacccuca      540

gcacaugcag cuccaucaac uacaucagca uuaacaccag gaccagcagc agcugcugca      600

gacgcagcag ccucaucagu agcaaaagga ggagcauaag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  2032
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt6)

<400>  2032
gggagaaagc uuaccaugca ccuauuagga uuuuucucag uagcauguuc auuacuugca       60

gcagcauuac uccccggacc aagagaagca ccagcugcag cagcagcauu cgaaucagga      120

cuagaccuaa gcgaugcaga accagacgca ggagaagcaa cagcauaugc aaguaaagac      180

cuagaagaac aauuaagaag uguaucauca guagacgaac uaaugacagu acucuacccc      240

gaauacugga aaauguacaa augccaauua agaaaaggag gauggcaaca caacagagaa      300

caagcuaacc uaaacucaag aacugaagaa acaauaaaau uugcagcagc ccacuacaau      360

acagaaauau uaaaaucaau cgauaacgaa uggcgaaaaa cacaauguau gccaagagaa      420

guuuguauag acguaggaaa agaauuugga guugcaacaa auacauuuuu uaaaccacca      480

ugcgucucag uauacagaug cggaggaugc ugcaauagcg aaggauuaca auguaugaau      540

acaucaacaa gcuacuuaag caaaacacua uuugaaauaa caguacccuu aucacaagga      600

cccaaaccag uuacaauaag uuuugcaaau cauacuucau gcagauguau gaguaaauua      660

gauguuuauc gccaaguaca uucaauaaua cgacgcaguc uaccagcaac auuaccacaa      720

ugccaagcug caaauaaaac augcccaacu aauuauaugu ggaauaauca caucugcaga      780

ugucuugcac aagaagacuu cauguuuucc ucagaugcag gagacgauuc aacagacggc      840

uuccacgaca uauguggacc aaauaaagaa cuagaugaag aaacauguca augcgucugc      900

agagcaggau uaagaccagc aucaugugga ccacacaaag aauuagacag gaauuccugc      960

caauguguau guaaaaauaa acuauuucca ucacaaugcg gagccaaucg agaauucgac     1020

gaaaauacau gccaaugugu cuguaaaaga accuguccca gaaaucaacc auuaaacccu     1080

ggaaaaugug ccugugaaug cacagaguca ccacaaaaau guuuacuaaa aggaaaaaaa     1140

uuccaucauc aaacaugcuc cuguuacaga agacccugca caaacagaca aaaagcaugc     1200

gaaccaggau ucagcuacag ugaagaagua ugcagaugug uaccaucaua uuggaaacga     1260

ccacaaaugu cauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  2033
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt6)

<400>  2033
gggagaaagc uuaccaugua cagagaaugg guaguaguaa acguauucau gaugcuauac       60

guacaauuag uacaagguuc cucaaacgaa cacggcccag uaaaaagauc aucccaaagc      120

acacuagaaa gaucugaaca acaaauaaga gcagcaucuu cacuagaaga acuuuuaaga      180

auaacacacu cagaagacug gaaacuaugg agaugcagac uaagacuaaa aucauucaca      240

ucuauggaca gcagguccgc aagucacaga ucaaccagau ucgccgcaac auuuuaugac      300

auagaaacac ucaaaguaau agacgaagaa uggcaaagaa cacaaugcag uccaagagaa      360

acauguguag aaguagccuc agaacuagga aaaagcacua acacauucuu caaaccacca      420

ugcguaaaug uauucagaug cggcggaugu ugcaacgaag aaucucucau auguaugaac      480

acaaguacau cauacaucuc aaaacaacua uucgaaauau cagucccauu aacaucagua      540

ccagaacuag uaccaguaaa aguagcaaac cacacaggau guaaaugccu accaacagca      600

ccaagacacc cauacaguau cauaagaaga ucaauccaaa uaccagaaga agaccgaugc      660

ucccacucaa aaaaauuaug cccaauagac augcuauggg auucaaacaa augcaaaugc      720

guacuacaag aagaaaaccc auuagcagga acagaagacc acucucacuu acaagaacca      780

gcauuaugcg gaccacauau gauguucgac gaagauagau gugaaugugu augcaaaacu      840

ccaugcccaa aagaccuaau acaacaccca aaaaacugcu cauguuucga augcaaagaa      900

ucucuagaaa caugcugcca aaaacacaaa uuauuucacc cagacacaug cucaugcgaa      960

gacagaugcc cuuuccacac cagaccaugu gccagcggaa aaacagcaug ugcaaaacac     1020

uguagauuuc caaaagaaaa acgagcagcc caaggaccac acucaagaaa aaauccauaa     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  2034
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt7)

<400>  2034
gggagaaagc uuaccaugga cagcgaugag accggcuucg aacacuccgg gcugugggug       60

aguguccucg ccggucuguu gcugggcgca ugccaggccc aucccauccc agacagcucc      120

ccgcuccugc aauuuggggg ccaggugagg cagcgguacu uguauacuga ugacgcgcag      180

caaaccgagg cccaccugga aauucgcgag gaugguacgg uagggggcgc agccgaccag      240

agucccgaaa gccuccugca gcugaaggca cucaaaccag gcgugaucca gauucugggg      300

gucaagacuu ccagguucuu gugucaacgg cccgauggug cccuguacgg cagccuccau      360

uuugacccag aggcgugcuc cuuccgcgag cugcuguugg aagaugggua uaacguguac      420

cagagugagg cccacggccu cccccugcau cugccaggua auaaaagccc gcacagggac      480

cccgcaccac gggggcccgc ccgcuuucuc ccacugcccg gcuugccgcc cgcccugcca      540

gaacccccag gcauccucgc accccagcca ccggaugugg gguccagcga cccccugagu      600

auggucgguc caucccaggg caggagcccc uccuaugcca guugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  2035
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt7)

<400>  2035
gggagaaagc uuaccaugca cagcuuuccc ccacugcucc uguugcuguu cuggggcgug       60

gucucccaua guuucccggc cacccucgag acucaggaac aagacgugga ucugguacag      120

aaguacuugg agaaauauua caaccugaag aaugacggga ggcaagugga aaaacggcgc      180

aacagcgguc ccgucgugga gaagcucaaa cagaugcagg aauuuuucgg ccugaaggug      240

accgggaagc cagaugcaga gacgcugaaa gucaugaagc agcccaggug cggcgugcca      300

gacguagccc aguuugugcu cacugagggu aauccccggu gggaacagac ccaccugacc      360

uaucgcaucg agaacuacac uccagauuug ccgagggcgg acgucgauca ugccauugaa      420

aaagcauucc aacugugguc caaugugacg ccccucaccu uuacuaaggu gagugagggg      480

caggccgaca ucaugauuag cuucguccgg ggcgaucacc gcgacaacuc cccauuugau      540

ggccccgggg guaaucuggc acaugccuuc cagccaggcc ccgggaucgg cggugacgcg      600

cacuuugaug aggacgaaag guggaccaac aauuuccggg aguauaaccu gcaccgcgug      660

gccgcacaug aauuggggca cagccucggc cugucccaua guacugacau uggcgcccug      720

auguacccga gcuauaccuu cuccggggau guacagcucg cccaagacga uaucgacggu      780

auccaggcaa uuuacggcag gagccagaau cccgugcaac caaucgggcc ccagacccca      840

aaagccugug auaguaagcu gacguuugac gcgauuacua ccauccgggg cgaggucaug      900

uucuuuaaag aucgcuucua caugaggacu aaccccuuuu auccagaagu ggaguugaau      960

uucauuuccg uguuuuggcc gcagcugccc aacggucucg aggccgcaua cgaguucgcc     1020

gaccgggaug aaguccgcuu uuucaagggc aauaaguauu gggcagugca ggggcaaaac     1080

guacugcacg gcuacccaaa agacaucuau agcuccuuug gguuccccag gaccgugaag     1140

cacauugaug ccgcccugag ugaagagaac accgguaaaa cuuacuuuuu cgucgcgaau     1200

aaguauuggc gguacgacga auacaaacgc agcauggacc caggcuaucc caagaugauc     1260

gcacaugauu ucccggggau cggccacaag guggacgccg ucuuuaugaa agaugguuuc     1320

uuuuacuucu uucauggcac gaggcaguau aaguucgacc caaaaaccaa gcggauuuug     1380

acucuccaga aagccaacuc cugguuuaau ugcaggaaga acugaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  2036
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt7)

<400>  2036
gggagaaagc uuaccaugca cagcuuuccc ccacugcucc uguugcuguu cuggggcgug       60

gucucccaua guuucgugcu caccgagggg aacccgaggu gggaacagac ucaccugacc      120

uaccggaucg agaauuauac gcccgacuug ccacgcgccg auguagacca ugcaauugaa      180

aaggccuuuc aacuguggag caacgugacu ccccucaccu ucaccaaagu cuccgagggu      240

caggcggaua ucaugauuag uuuugugagg ggcgaccacc gggauaauag cccauucgac      300

gggcccggcg guaaccuggc ccaugcauuu cagccagggc cgggcaucgg cggggaugcc      360

cacuucgacg aagaugagcg cuggacuaau aacuuuaggg aguacaaucu gcaccgggug      420

gcagcccaug aacucgguca cucccugggc uugagccauu ccaccgacau uggggcgcug      480

auguauccca guuacacguu cagcggcgau guccagcucg cccaagacga uaucgacggu      540

auccaggcaa uuuaugggcg cucccagaac ccagugcagc ccaucggccc acaaacuccc      600

aaggccugcg acagcaaacu gaccuuugau gccauuacua ccaucagggg cgagguaaug      660

uucuucaagg accgguuuua caugcgcacc aauccguucu aucccgaagu ggagcugaac      720

uuuauuagug ucuucuggcc acaguugccc aaugggcucg aggcagccua cgaauuugcg      780

gauagggacg aggugcgguu cuuuaaaggu aacaaguacu gggccgugca gggccagaau      840

guccugcacg gguauccaaa ggauaucuac uccagcuucg gcuuuccccg cacggugaaa      900

cacauugacg cagcccuguc cgaagagaac acugguaaga ccuauuucuu uguagcaaau      960

aaauacugga gguaugauga auacaagcgg aguauggacc caggcuaucc gaaaaugauc     1020

gcccaugauu uccccgggau cggccacaag guggacgccg ucuuuaugaa agauggguuc     1080

uucuacuuuu uccaugguac ucgccaauac aaguuugacc caaagaccaa aaggauucuc     1140

acccugcaga aggcgaacag cugguucaac ugucggaaaa auugaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  2037
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt7)

<400>  2037
gggagaaagc uuaccaugaa gaaaaacauc cugaagauuc ucauggacag cuacuccaaa       60

gagaguaaga uccagaccgu gaggcggguc acuagcgugu cccuguuggc cguauaucug      120

accaugaaua cgaguagccu cgugcuggca aaacccauug aaaacacuaa ugauaccucc      180

aucaagaacg ucgagaaguu gcgcaaugcc ccaaacgaag agaauagcaa aaagguggaa      240

gacuccaaaa acgauaaggu ggagcacguc aaaaauauug aggaagcgaa gguggagcaa      300

guagccccgg aagugaaaag uaagagcacc cugagguccg caagcaucgc caacacuaau      360

agugagaagu acgacuucga guaucucaac ggccuguccu acaccgaacu gacgaaucuc      420

aucaaaaaca uuaaguggaa ucagaucaac gggcuguuua acuauagcac ugguucccag      480

aaauucuuug gcgauaagaa ucggguccag gcaauuauca acgccuugca agagaguggg      540

cgcaccuaca cugcgaauga caugaaaggc auugaaaccu ucaccgaggu gcugagggcc      600

gguuuuuauc ucggguacua caacgauggc cugagcuauc ugaaugaccg gaacuuccag      660

gauaagugca uccccgcaau gauugccauc cagaagaauc caaacuuuaa auugggcacg      720

gccgugcagg acgaagucau cacuucccuc gggaagcuga uugguaaugc aagcgccaac      780

gcggaggugg uaaauaacug ugugcccguc cugaaacaau uccgcgagaa ucucaaccag      840

uacgccccag auuaugugaa gggcaccgca gugaaugaac ugaucaaagg gauugaguuu      900

gacuucagug gcgccgcaua cgaaaaggau gucaagacua ugcccuggua ugguaaaauc      960

gacccauuua uuaacgaguu gaaggcccug gggcucuacg gcaacaucac cuccgccacc     1020

gaaugggcga gcgacguggg caucuauuac cugaguaaau ucgggcugua cuccacuaau     1080

aggaacgaua uuguacagag cuuggagaag gcaguggaca uguauaaaua cgguaagauc     1140

gccuucgucg ccauggagcg gauuacgugg gauuaugacg gcaucgggag caauggcaag     1200

aaaguggauc augacaaguu ucucgaugac gcagaaaaac acuaccugcc gaagaccuau     1260

acuuucgaua acgguaccuu uauuauccgc gccggcgaca aagucuccga ggaaaagauc     1320

aaaaggcugu acugggcgag ucgggaggua aagagccagu uccaucgcgu gguggggaau     1380

gauaaggccc ucgaaguggg caacgcagac gacguccuga ccaugaaaau uuuuaauucc     1440

cccgaggagu auaaguucaa cacuaauauc aacgggguga gcacggauaa ugguggcuug     1500

uacauugaac caagggggac cuuuuacacu uaugagcgga cuccccaaca gaguaucuuc     1560

ucccuggagg aacucuuucg ccacgaguac acccauuauc ugcaggccag guaccugguc     1620

gacggcuugu ggggucaagg cccauucuau gagaaaaacc ggcucaccug guuugaugaa     1680

gggacggcag aguucuuugc cggcagcacc cgcacuuccg gggugcugcc caggaagagu     1740

auucugggcu accucgccaa agacaaggug gaucaccggu auagccugaa gaaaaccuug     1800

aacuccgguu acgacgauag cgacuggaug uucuacaauu auggguucgc aguagcccac     1860

uaccuguaug aaaaggauau gccgacuuuu aucaaaauga auaaggcgau ucucaacacc     1920

gacgugaaaa guuacgauga aaucaucaag aagcuguccg acgaugccaa caaaaauacg     1980

gaguaucaga accauauuca ggagcuggca gacaaguacc agggcgccgg uauccccuug     2040

gucagcgacg auuaucugaa agaccacggc uacaagaaag ccuccgaagu guacagugag     2100

auuagcaagg cagcgucccu caccaauacu agcgucaccg ccgagaaaag ucaauauuuc     2160

aacacuuuua cccugagggg gacguacacc ggcgaaacuu ccaaggggga guucaaggau     2220

ugggacgaaa ugagcaaaaa gcucgauggc acccuggagu ccuuggccaa aaauagcugg     2280

agugguuaua agacucugac cgcauacuuu acgaacuauc gcgugaccag cgacaauaaa     2340

gugcaguacg auguagucuu ccauggggug cucacugaca acgccgauau cuccaauaac     2400

aaggcaccaa uugccaaggu gaccggcccc aguacuggcg cggucgggcg gaauaucgaa     2460

uuuagcggua aagacuccaa ggaugaggac ggcaaaaucg ugagcuacga cugggauuuc     2520

ggggacggcg ccaccuccag ggguaagaac agugugcacg cauauaaaaa ggccgggacg     2580

uacaauguaa cccugaaggu cacugaugac aaaggcgcca ccgcaacuga gagcuuuacc     2640

auugaaauca agaacgaaga uacuaccacg ccaauuacca aagagaugga gcccaaugac     2700

gauaucaagg aagccaacgg cccaauugug gaggggguga cugucaaagg ugaccugaac     2760

ggcuccgaug acgcggauac cuucuauuuu gacgugaagg aagaugggga cguaacuauc     2820

gaguugccgu acaguggcag cuccaauuuc accuggcugg uguauaaaga gggugacgau     2880

cagaaccaca ucgccagcgg gauugacaag aauaacagua aggucggcac guucaaaucc     2940

accaagggcc gccauuacgu guuuaucuau aaacacgaua gcgcauccaa uauuagcuac     3000

agucucaaca ucaaggggcu ggguaaugaa aaacucaagg agaaggaaaa caaugacucc     3060

agcgauaaag ccacugugau ucccaacuuc aauaccacua ugcagggcag ucuguugggg     3120

gacgauuccc gggacuacua uagcuuugag gucaaggaag agggcgaggu gaacaucgaa     3180

cuggauaaaa aggacgaguu cgguguaacc uggacgcugc auccagaauc caauauuaac     3240

gauaggauca ccuacgggca aguggacggc aauaaaguca gcaacaaggu gaagcuccgc     3300

cccggcaaau auuaccuguu gguguauaag uacaguggga gcgguaacua ugagcugcgg     3360

gucaauaaau gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  2038
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt7)

<400>  2038
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuucu guucuccagu       60

gccuacagca uugcaaacac uaauuccgag aaauaugacu uugaauacuu gaacggccug      120

aguuauaccg agcucacgaa ucugaucaag aacauuaaau ggaaucagau caacggguug      180

uucaauuaca gcacugguuc ccaaaaguuu uucggcgaua aaaacagggu ccaggccauu      240

aucaaugcgc ugcaggaaag cgggcggacc uauaccgcca acgacaugaa gggcaucgag      300

acuuuuaccg aagugcuccg cgcagguuuc uaccuggggu auuacaauga uggccugucc      360

uaccucaacg acaggaauuu ucaggauaag ugcauucccg ccaugaucgc aauucagaaa      420

aacccaaauu ucaagcuggg cacggccgua caggacgagg ugaucacuag cuuggggaaa      480

cugauuggua acgcgagcgc caacgcagag gucgugaaua acugugugcc gguccucaag      540

caguuucggg aaaaucugaa ccaguaugcc cccgauuacg ugaaaggcac cgccguaaau      600

gagcugauca aggggauuga guucgacuuc uccggcgcag ccuaugaaaa agaugugaag      660

acuaugccau gguacgguaa gaucgacccc uuuaucaacg aguugaaagc gcucgggcug      720

uauggcaaua uuaccagcgc caccgaaugg gcaagugaug ucggcaucua cuaucugucc      780

aaguucgggc ucuacagcac gaaccgcaau gacauugugc aaucccugga gaaagccgug      840

gauauguaca aguaugguaa aaucgcauuu gucgccaugg aaaggauuac uugggacuac      900

gacggcaucg ggaguaacgg caagaaggug gaucacgaca aauucuugga ugacgccgag      960

aagcauuauc ugccaaaaac cuacacuuuu gauaauggua ccuucaucau ucgggcgggc     1020

gacaagguaa gcgaagagaa aaucaagcgc cucuauuggg cauccaggga ggugaagagu     1080

caguuucacc gggucguggg gaacgauaaa gcccuggaag ugggcaaugc cgacgauguc     1140

cugaccauga agauuuucaa cagucccgag gaauacaaau uuaauacuaa caucaacggg     1200

guguccacgg acaauggugg cuuguauauu gagccacgcg ggaccuucua cacuuacgaa     1260

aggaccccgc agcagagcau cuuuagucuc gaggagcugu uccggcauga auauacccac     1320

uaccugcaag cacgcuaucu cguagauggc cugugggguc agggccccuu uuacgagaag     1380

aacagguuga cuugguucga cgaagggacg gccgaguucu uugcgggcuc cacccggacu     1440

agcggggugc ugccacgcaa aagcauccuc ggcuaucugg ccaaggacaa ggucgaucau     1500

agguacuccc ugaaaaagac cuugaauagu gguuaugacg auagcgacug gauguucuac     1560

aacuacgggu uugcaguggc ccacuaucuc uacgaaaaag auaugcccac cuucauuaag     1620

augaauaaag caauccugaa cacugacguc aaguccuaug augagauuau caaaaagcug     1680

agcgacgaug ccaauaagaa cacggaguac cagaaucaca uucaagaacu cgccgacaaa     1740

uaucagggcg cagguauccc acuggugagu gaugacuacu ugaaggauca uggcuauaaa     1800

aaggccuccg agguguacag cgaaauuucc aaagcggcca gucugaccaa cacuagcgua     1860

accgcagaga agucccagua cuuuaauacu uucacccucc gggggacgua uaccggcgag     1920

acuagcaagg gggaauuuaa agacugggac gagaugagua agaaacugga uggcacccug     1980

gaauccuugg ccaagaacag cugguccggu uacaaaacuc ugaccgccua uuucacgaau     2040

uaccgcguga ccagugacaa caagguccag uaugaugugg ucuuucacgg ggugcucacu     2100

gacaaugcag auaucagcaa caacaaggcg cccaucgcca aagugaccgg cccguccacu     2160

ggcgcaguag ggaggaauau ugaguucagc gguaaggaca guaaagauga agacggcaag     2220

aucguguccu acgauuggga cuuuggggau ggcgccacca gccgggguaa aaacuccguc     2280

caugccuaca agaaagcagg gacguauaau gugacccuga aggucacuga cgacaagggc     2340

gccaccgcga cugagagcuu caccauugag aucaaaaacg aagauacgac cacucccauu     2400

accaaggaga uggaaccaaa ugacgauauc aaagaggcca acggccccau cguggaaggg     2460

gugacuguaa agggugaccu caauggcagu gaugacgcag auaccuucua cuuugacguc     2520

aaagaggaug gggacgugac uauugagcug ccauauagcg gcuccaguaa cuucaccugg     2580

uugguguaca aggaagguga ugaccaaaau cacaucgcca gcgggauuga uaagaacaau     2640

uccaaagucg gcacguuuaa gagcaccaaa ggcaggcacu auguguucau cuacaagcau     2700

gacuccgcca guaacauuag cuauucccug aauaucaaag ggcucgguaa cgagaagcug     2760

aaggaaaaag agaauaacga caguagcgau aaggcaacug ugauccccaa cuuuaauacc     2820

acuaugcagg gcucccuguu gggggacgau agccgcgacu acuacaguuu cgaaguaaaa     2880

gaggagggcg aagucaacau ugagcuggau aagaaagacg aauuuggugu gaccuggacg     2940

cuccacccag aguccaauau caacgaucgg auuaccuaug ggcaagugga cggcaauaag     3000

gucagcaaca aagugaagcu gaggccgggc aaguacuauc uccugguaua caaauauucc     3060

gggagcggua auuacgaguu gcgcgugaac aagugaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  2039
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt7)

<400>  2039
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuucu guucuccagu       60

gccuacagca ugaaaaagaa cauuuugaaa auccugaugg acuccuauag uaaggagagc      120

aaaauucaga cugucaggcg ggugaccucc guaagccucc uggcagugua cuugacgaug      180

aauacuucca gucugguccu cgccaagccc aucgaaaaca ccaaugauac cagcauuaag      240

aacguggaga aacugcgcaa ugcgccaaac gaagaaaauu ccaagaaagu ggaagacagc      300

aagaacgaua aagucgagca cgugaagaau aucgaggaag ccaaaguaga gcaaguggca      360

ccggaaguca agaguaaguc cacucugagg agcgccuccc ggcgcaggcg gaaacgcauc      420

gcaaacacca auagugagaa guaugacuuu gaguaccuca acggccugag cuauacggaa      480

uugacuaauc ugauuaaaaa caucaagugg aaucagauua acggucucuu caacuacucc      540

accgggagcc agaaauuuuu cggcgauaag aauagggugc aggccaucau uaacgcgcug      600

caagagagug ggcggacuua uaccgccaau gacaugaagg gcaucgaaac cuuuacggag      660

gugcugcgcg cagguuucua cuugggguac uauaacgaug gccucuccua ccugaaugac      720

aggaacuuuc aggauaaaug cauucccgcc augaucgcca uccagaagaa uccaaacuuc      780

aaacugggca cugcagucca ggacgaagug auuaccagcc ucgggaagcu gaucgguaau      840

gccagugcga acgccgaggu agugaauaac uguguccccg uguugaaaca auuucgggag      900

aaucugaacc aguaugcacc agauuacgug aagggcacug ccgucaauga acucauuaag      960

gggaucgagu ucgacuucuc cggcgcagcc uaugaaaaag augugaagac caugcccugg     1020

uacgguaaaa uugacccauu uaucaacgag cugaaggccc ugggguugua uggcaacauc     1080

accagcgcga cugaaugggc aagcgacgua ggcauuuacu accucuccaa auucgggcug     1140

uauaguacga aucgcaacga uaucgugcag agccuggaga aggccgucga cauguacaag     1200

uaugguaaaa uugccuuugu ggcaauggag aggaucaccu gggauuacga cggcauuggg     1260

uccaauggca agaaagucga ucaugacaag uuccucgaug acgccgaaaa acacuaucug     1320

ccgaagacuu acaccuuuga uaacgguacc uucaucaucc gggcgggcga caaagugagc     1380

gaggaaaaga uuaagcgcuu guauugggcc aguagggagg ugaaauccca guuucaucgg     1440

guagugggga augauaaggc acuggaaguc ggcaacgccg acgacgugcu cacuaugaaa     1500

aucuucaaua gccccgagga guacaaguuu aacacgaaua uuaacggggu cuccaccgau     1560

aaugguggcc uguacaucga accacgcggg acuuucuaua ccuacgagag gacuccccaa     1620

cagaguauuu uuagccugga agaguuguuc cggcacgagu auacccauua ccuccaggca     1680

agguaucugg uggacggccu guggggucaa ggcccauuuu acgagaaaaa ccgccucacg     1740

ugguucgaug aggggaccgc cgaguucuuu gccggcucca cucggaccag cggggugcug     1800

cccaggaaga guaucuuggg cuaucuggca aaggacaaag uagaucaccg cuacucccuc     1860

aagaaaacuc ugaauagcgg uuacgacgau uccgacugga uguucuauaa cuacggguuu     1920

gccguggcgc acuaucugua cgaaaaggau augccgaccu ucauuaaaau gaauaaggcc     1980

aucuugaaca cggacgucaa gaguuaugau gaaaucauua aaaagcugag cgacgaugca     2040

aacaaaaaua ccgaguacca gaaccauauc caggagcucg ccgacaagua ucagggcgcc     2100

gguauucccc ugguguccga cgauuaccuc aaagaccacg gcuacaagaa agcaagcgaa     2160

gucuauagug agaucuccaa ggcggccagc cugacuaaua ccuccgugac ugcagaaaag     2220

agccaauacu uuaacaccuu cacguugcgg gggaccuaua cuggcgagac caguaaaggg     2280

gaauuuaagg auugggacga gaugagcaaa aagcuggaug gcacucucga gucccuggcc     2340

aaaaauaguu ggagcgguua caagacccug acggccuauu ucaccaacua cagggugacu     2400

uccgacaaua agguacagua cgaugucgug uuucaugggg uguugaccga caacgcagau     2460

auuagcaaua acaaagcccc aaucgcgaag gucacuggcc ccuccaccgg cgccgugggg     2520

cgcaauaucg aguucagugg uaaagacagc aaggaugaag acggcaaaau uguguccuau     2580

gacugggauu uuggggacgg cgcaacgagu cgggguaaga acagcguaca cgccuacaag     2640

aaagccggga ccuauaaugu cacucugaag gugaccgaug acaaaggcgc aacugccacc     2700

gaauccuuca cuaucgagau uaagaacgaa gauaccacga ccccaaucac uaaagagaug     2760

gagcccaaug acgauauuaa ggaagcgaac ggcccaaucg uggagggggu caccgugaaa     2820

ggugaccuca acggcagcga ugacgccgau acuuucuacu uugacguaaa ggaagauggg     2880

gacgugacca ucgagcugcc guauaguggc uccagcaauu ucacguggcu cgucuacaag     2940

gagggugacg aucagaacca cauugcaucc gggaucgaca aaaauaacag caaggugggc     3000

accuuuaaaa guacuaaggg caggcauuau guguucauuu acaaacacga uuccgccagc     3060

aauaucaguu acucccugaa cauuaagggg uuggguaaug aaaagcugaa agagaaggaa     3120

aacaaugaca gcuccgauaa agcaaccguc auccccaacu uuaauacuac caugcagggc     3180

agccugcucg gggacgauag ucgggacuau uacagcuucg aggugaagga agagggcgag     3240

guaaacauug aacuggauaa aaaggacgag uuugguguga cguggaccuu gcauccagaa     3300

uccaauauca acgaucgcau cacuuauggg caagucgacg gcaauaaggu gaguaacaaa     3360

gugaagcuga ggcccggcaa auacuaucuc cuggucuaca aguauagcgg guccgguaac     3420

uacgagcucc gggugaauaa augaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  2040
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt7)

<400>  2040
gggagaaagc uuaccaugaa cuuccugaag aucauucuca auaggggcaa aaccaugaag       60

cggaaaugcc ugagcaagcg cuugaugcug gccaucacua uggcaaccau uuuuacggug      120

aacuccacuc uccccaucua cgccgcgguc gacaaaaaua acgccaccgc agccgugcag      180

aaugagagua agagguauac cguaagcuac cugaagacuu ugaacuauua cgaucuggug      240

gaccuccugg ucaaaaccga aauugagaau cugccagauc ucuuccaaua uuccagugac      300

gcaaaggaau uuuacgggaa caaaacgcgg augagcuuca ucauggauga gaucggucgc      360

agggccccgc aguauacuga aauugaccac aagggcaucc ccacccuggu ggaggugguc      420

cgggcggggu uuuacuuggg cuuccauaau aaagagcuga acgaaauuaa uaagcgcucc      480

uuuaaagaga gggugauccc aagcauucuc gccauccaga agaaccccaa uuucaagcug      540

gguacugaag uacaggauaa aauugugucc gcaaccgggc uguuggccgg caacgagacc      600

gccccacccg aggucgugaa uaacuuuacg ccaauccucc aagacuguau caagaacauu      660

gaucgguacg cacuggacga ucugaaaagu aaggcccucu ucaaugugcu ggcggccccg      720

acuuaugaca ucaccgaaua cuugcgcgca acuaaagaga agcccgaaaa caccccaugg      780

uauggcaaga uugauggguu uaucaaugag cugaaaaagc ucgcccugua cgguaaaauu      840

aacgacaaua acagcuggau caucgacaau ggcauuuauc acaucgcacc ccuggggaag      900

uugcauucca acaauaaaau uggcaucgaa acccucacug aggucaugaa gguguaccca      960

uaucugagca ugcagcaucu gcagagugcc gaucagauua agaggcacua cgacuccaaa     1020

gaugccgagg guaacaagau cccccucgac aaauucaaga aagaagggaa ggagaaguac     1080

ugcccgaaaa cguauaccuu cgaugacggc aagguaauca uuaaagcggg cgcacgggug     1140

gaagaggaaa aggucaaacg ccuguacugg gccagcaagg aggugaauag ucaauuuuuc     1200

aggguguaug ggaucgauaa acccuuggag gaagguaacc cagacgauau ucugacuaug     1260

gucaucuaca auagucccga ggaauauaag cucaacagcg ugcuguacgg cuaugacacc     1320

aauaacgggg gcauguacau ugagccagaa gguaccuuuu ucacuuacga gcgggaggcc     1380

caggaaucca cguauacccu ggaggaauug uuucgccacg aguacacuca cuaucuccag     1440

ggcagguacg caguacccgg gcaguggggc cggaccaagc uguaugauaa cgaccgccug     1500

accugguacg aggaaggggg ugccgaacuc uucgcgggca gcacuaggac gagugggauc     1560

cugccacgga aauccauugu gagcaauauc cauaacacca cuaggaauaa ccgcuauaag     1620

uugagugaca ccguccacuc caaauacggc gccagcuuug aguucuacaa uuaugcaugu     1680

auguuuaugg auuacaugua uaacaaggac auggguaucc ugaauaaacu caacgaucug     1740

gccaagaaua acgacgugga uggcuacgac aauuauauuc gggaucugag cuccaacuac     1800

gcauugaaug acaaguauca agaucauaug caggagagga ucgacaacua cgaaaaucug     1860

acugucccgu ucguggccga ugacuaccuc gugcgccacg ccuauaaaaa ccccaacgag     1920

auuuacagug agaucagcga aguagcaaag cugaaagaug ccaaguccga ggugaaaaag     1980

agccaguauu uuaguaccuu cacgcuccgg ggguccuaca ccggcggggc gagcaagggc     2040

aaacuggaag accaaaaggc caugaauaaa uuuauugacg auuccuugaa gaaacuggac     2100

acuuauaguu ggagcgguua caagacccuc acugcauacu ucaccaacua uaaagucgau     2160

uccagcaaua gggugacgua cgacgucgug uuccacgggu aucugccaaa cgagggcgau     2220

aguaaaaauu cccugcccua cgguaagauc aacggcaccu auaaggggac ugaaaaggag     2280

aaaaucaagu uuagcuccga gggcaguuuc gacccagaug ggaaaauugu gagcuacgaa     2340

ugggacuuug gcgaugguaa uaaguccaac gaggaaaauc ccgagcauag cuaugacaag     2400

guagggaccu acacugugaa auugaagguc accgaugaca aaggcgaaag uuccgugagc     2460

acgaccacug ccgagaucaa ggaccugucc gagaacaaac ucccggucau uuacaugcac     2520

gugccaaaga gcggcgcccu gaaucagaag gugguauucu augggaaagg uaccuacgau     2580

cccgacggca guaucgcagg guaucagugg gauuuuggcg acgguagcga uuucuccagu     2640

gaacagaacc ccagccaugu cuacacuaag aaaggggagu auaccgugac gcuccgcgug     2700

auggacucca gcggccaaau guccgaaaag accaugaaaa uuaagaucac ugauccaguc     2760

uaccccaucg gcaccgagaa agagccaaau aacaguaagg aaacugcgag cgggccgauu     2820

gugcccggua ucccaguguc cggcaccauu gagaauacuu ccgaccagga uuauuuuuac     2880

uucgacguaa ucacccccgg ggaagucaag auugauauca acaaacuggg cuacgguggg     2940

gccacguggg ugguguauga cgagaacaau aacgcaguca gcuacgccac cgaugacggc     3000

cagaauuugu ccggcaaguu uaaagccgac aagccagggc gguauuacau ucaccuguau     3060

auguucaacg guagcuacau gcccuauagg aucaauaucg aaggcagugu ggggcgguga     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  2041
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt7)

<400>  2041
gggagaaagc uuaccaugaa gaggaaaugc cugagcaagc ggcucaugcu ggccaucacc       60

auggcaacua uuuucaccgu gaacuccacg uugcccaucu acgccgcggu cgacaaaaau      120

aacgccacug cagccgugca gaaugagagu aagcgcuaua ccguaagcua ccugaaaacc      180

cucaacuauu acgaucuggu ggacuugcug gucaagacug aaauugagaa ucucccagau      240

cuguuucaau auuccaguga cgcaaaggag uucuacggca acaaaaccag gaugagcuuu      300

aucauggaug aaauugggcg gcgcgccccg caguauacgg aaaucgacca caaggguauc      360

cccacucugg uggagguggu cagggcgggc uucuaccucg gguuucauaa uaaagagcug      420

aacgaaauua auaagcgguc cuucaaagag cgcgugaucc caagcauuuu ggccauccag      480

aagaacccca auuuuaaacu gggcaccgaa guacaggaua agauuguguc cgcaacuggu      540

cuccuggccg ggaacgagac cgccccaccc gaggucguga auaacuucac cccaauccug      600

caagacugua uuaagaauau cgauagguac gcauuggacg aucucaaaag uaaggcccug      660

uuuaacgugc uggcggcccc gacguaugac aucacugaau accuccgggc aaccaaagag      720

aagcccgaaa acacuccaug guauggcaaa auugauggcu ucaucaauga gcugaagaag      780

uuggcccugu acgggaaaau uaacgacaau aacagcugga ucauugacaa ugguaucuau      840

cacaucgcac cccucggcaa gcugcauucc aacaauaaaa uugggaucga aacccugacc      900

gaggucauga agguguaccc auauuugagc augcagcacc uccagagugc cgaucagauu      960

aaacgccauu acgacuccaa ggaugccgag ggcaacaaga ucccccugga caaauuuaag     1020

aaagaaggua aggagaaaua cugcccgaag acuuauacgu ucgaugacgg gaagguaauu     1080

aucaaagcgg gcgcaagggu ggaagaggaa aaggucaaac ggcuguacug ggccagcaag     1140

gaggugaaua gucaauucuu ucgcguguau ggcaucgaua aaccccucga ggaagggaac     1200

ccagacgaua uucugaccau ggucaucuac aauagucccg aggaauauaa guugaacagc     1260

gugcuguacg guuaugacac uaauaacggc gggauguaca uugagccaga aggcaccuuc     1320

uuuaccuacg agagggaggc ccaggaaucc acuuauacgc ucgaggaacu guuccggcac     1380

gaguacaccc acuaucugca gggucgcuac gcaguacccg gccagugggg gaggacuaaa     1440

uuguaugaua augaccggcu caccugguac gaggaaggcg gggccgagcu guuugcgggu     1500

agcacccgca cuuccggcau ccugccaagg aaguccauug ugagcaacau ccauaacacg     1560

acccggaaua acagguauaa gcucagugac acuguccacu ccaaauacgg ggccagcuuc     1620

gaauuuuaca auuaugcaug uauguucaug gauuacaugu auaacaagga caugggcauu     1680

cugaauaaau ugaacgaucu ggccaagaau aacgacgugg augguuacga caauuauauc     1740

cgcgaucuca gcuccaacua cgcacugaau gacaaauauc aagaucauau gcaggagcgg     1800

aucgacaacu acgaaaaucu gaccgucccg uuuguggccg augacuacuu ggugaggcac     1860

gccuauaaga accccaauga gauuuacagu gagaucagcg aaguagcaaa gcugaaagau     1920

gccaaguccg aggugaaaaa gagccaguau uucaguacuu uuacccuccg cggcuccuac     1980

acgggcggcg cgagcaaagg gaagcuggaa gaccaaaagg ccaugaacaa auucauugac     2040

gauucccuca agaaacugga caccuauagu uggagcggcu acaagacuuu gaccgcauac     2100

uuuacuaacu auaaagucga uuccagcaau cgggugaccu acgacgucgu guuccacggu     2160

uaucugccaa acgaggggga uaguaaaaau ucccuccccu acggcaagau caacgguacg     2220

uauaagggca ccgaaaagga gaaaauuaag uucagcuccg aggggaguuu ugacccagau     2280

ggcaaaaucg ugagcuacga augggacuuc ggggauggca auaaguccaa cgaggaaaau     2340

cccgagcaua gcuaugacaa aguagguacu uacaccguga agcugaaggu cacugaugac     2400

aaaggggaaa guuccgugag caccacgacc gccgagauca aggaccuguc cgagaacaaa     2460

uugccgguca uuuacaugca cgugccaaag agcggcgccc ugaaucagaa agugguauuu     2520

uauggcaagg ggacuuacga ucccgacggu aguaucgcag gcuaucagug ggauuucggg     2580

gacggcagcg auuuuuccag ugaacagaac cccagccaug ucuacaccaa gaaaggugag     2640

uauacuguga cccucagggu gauggacucc agcgggcaaa uguccgaaaa gacgaugaaa     2700

auuaagauca ccgauccagu cuaccccauu ggcacugaga aagagccaaa uaacaguaag     2760

gaaaccgcga gcggcccgau cgugcccggg aucccagugu ccgguacuau ugagaauacc     2820

agugaccagg auuauuucua cuuugacgua aucacucccg gcgaagucaa aauugauauc     2880

aacaagcugg gguacggcgg ugccaccugg gugguguaug acgagaauaa caacgcaguc     2940

agcuacgcca cggaugacgg gcagaaucuc uccggcaagu ucaaagccga caagccaggc     3000

cgcuauuaca uucaccugua uauguuuaac gggagcuaca ugcccuaucg gaucaauauu     3060

gaagguagug uggggaggug aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  2042
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt7)

<400>  2042
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuucu guucuccagu       60

gccuacagcg uccagaacga guccaaaagg uauacuguga guuacuugaa gacccugaau      120

uauuacgacc ucguagaucu guuggugaaa acggaaauug agaaccugcc cgaccucuuu      180

caauauagcu ccgaugcaaa ggaguucuac ggcaauaaaa cucggaugag cuuuaucaug      240

gacgaaauug ggcgcagggc cccacaguau accgaaaucg aucacaaggg uauuccgacc      300

cuggucgagg uggugcgggc gggcuucuac cugggguuuc auaacaagga gcucaaugaa      360

aucaacaaac gcuccuucaa ggagaggguc auccccagua uucuggccau ccagaaaaau      420

ccaaacuuua aguugggcac ugaagugcag gacaaaauug uaagcgcaac cggucugcuc      480

gccgggaaug agacggcacc cccagaggug gucaacaauu ucacucccau ccugcaagau      540

ugcauuaaga acaucgaccg guacgcccug gaugacuuga aauccaaggc gcucuuuaau      600

gugcuggccg caccaaccua ugauauuacu gaauaccugc gcgccaccaa ggagaaaccg      660

gaaaacaccc ccugguaugg caagaucgac ggcuucauca augagcucaa aaagcuggcc      720

uuguacggga aaauuaacga uaacaauagc uggaucauug acaacgguau cuaucacauu      780

gcaccacugg gcaagcucca uaguaauaac aagaucggga ucgaaacgcu gacugaggug      840

augaaagucu accccuaucu guccaugcag cacuugcaga gcgccgacca gauuaagagg      900

cauuacgauu ccaaagacgc ggagggcaau aagaucccac ucgauaaauu caagaaggaa      960

gguaaagaga aguacugucc caaaaccuau acuuuugacg augggaaggu gauuaucaaa     1020

gccggcgcac ggguagaaga ggaaaaggug aagcgccugu acugggccag uaaagagguc     1080

aacagccaau ucuuuagggu guauggcauu gacaagccgc uggaggaagg gaaucccgau     1140

gacauccuca ccauggugau cuacaacucc ccagaggaau auaaacugaa uagcgucuug     1200

uacgguuaug auaccaacaa uggcgggaug uacauugagc ccgaaggcac uuucuuuacg     1260

uacgagcggg aggcacagga aaguaccuau acucuggagg aacucuuccg ccacgaguac     1320

acccacuauc ugcaggguag guacgccgug ccaggccagu gggggcggac caagcuguau     1380

gacaacgauc gcuugacuug guacgaggaa ggcggggccg agcucuuugc ggguuccacg     1440

aggaccagcg gcauccugcc ccggaaaagu auuguaucca auauccauaa cacuacccgc     1500

aauaacaggu auaagcugag cgacaccgug cacagcaaau acggggcauc cuucgaauuu     1560

uacaacuaug ccugcauguu cauggacuac auguauaaua aggauauggg cauucucaac     1620

aagcugaaug acuuggccaa aaacaaugau gucgacgguu acgauaacua uauccgggac     1680

cugaguagca auuacgcacu caacgauaag uaucaagacc auaugcagga gaggauugau     1740

aauuacgaaa accugacugu gccauuuguc gccgacgauu accuggugcg ccacgcguau     1800

aaaaauccga acgagaucua cuccgagauc agcgaagugg ccaaguugaa agacgcaaag     1860

agugagguaa agaaauccca guauuucagc acguuuaccc ugcggggcuc cuacacuggg     1920

ggcgccagua aggggaaacu cgaagaucaa aaggcaauga auaaauucau ugacgacagc     1980

cugaagaagc ucgauaccua uuccuggagc ggcuacaaaa cucugaccgc cuacuucacg     2040

aacuauaagg uggacaguuc caauaggguc accuacgaug uggucuuuca cgguuauuug     2100

cccaacgagg gggacagcaa aaacucccug ccauacggca agaucaaugg uacuuauaaa     2160

ggcaccgaaa aggagaaaau uaaguucagu agcgaggggu ccuuugaucc cgacggcaag     2220

aucgugagcu acgaauggga uuucggggac ggcaacaaaa guaaugagga aaacccagag     2280

cauuccuaug auaagguggg uacuuacacc guaaaacuca aggugacgga cgauaaaggg     2340

gaaagcuccg ucagcaccac uaccgccgag auuaaggacc ugagugagaa uaagcugccc     2400

gugaucuaca ugcacguccc gaaaagcggc gcauugaacc agaagguggu guuuuauggc     2460

aaagggacuu acgacccaga ugguuccauc gccggcuauc agugggacuu cggggauggc     2520

agugacuuua gcuccgaaca gaaucccagc cauguauaca ccaagaaagg ugaguauacg     2580

gucacccugc gcgugaugga uuccaguggg caaaugagcg aaaagacuau gaagauuaaa     2640

aucaccgacc ccguguaccc aauuggcacu gagaaggagc ccaacaauuc caaagaaacc     2700

gcgaguggcc caaucguccc ggggauuccc gugagcggua cgaucgagaa caccuccgau     2760

caggacuauu ucuacuuuga ugugaucacu ccaggcgaag uaaagauuga caucaauaaa     2820

cucggguacg gcggugccac cugggucgug uaugaugaga acaauaacgc agugagcuac     2880

gccacugacg augggcagaa ucugaguggc aaguucaaag ccgacaagcc cggccgguau     2940

uacauucacc ucuauauguu uaacgggucc uacaugccau auaggaucaa cauugaaggu     3000

agcgucggcc gcugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2043
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt7)

<400>  2043
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcucuuucu guucuccagu       60

gccuacagca ugaaaaggaa gugcuugucc aaacggcuga ugcucgcaau uacuauggcc      120

accaucuuua cggucaacag uacucugccc auuuaugcgg ccguggacaa gaauaacgca      180

accgccgcac gcaggcggcg caaaagggua cagaaugaga gcaagcggua caccgugucc      240

uauuugaaga cucugaacua cuaugaucuc gucgaccugc uggugaaaac cgaaaucgag      300

aaucucccag aucuguucca auacagcucc gacgccaagg aauuuuaugg caacaaaacg      360

cgcaugaguu ucauuaugga ugagaucggg aggcgggcgc cgcaguacac ugaaaucgac      420

cacaagggua uucccaccuu gguggagguc gugcgcgccg gcuuuuaccu gggguuccau      480

aauaaagagc ucaacgaaau caauaagagg agcuuuaaag agcggguaau uccauccauc      540

cuggcaauuc agaagaaccc caauuucaag cugggcacug aagugcagga uaaaaucguc      600

agcgccaccg guuugcucgc cgggaacgag accgcaccac ccgagguggu gaauaacuuu      660

acgccaauuc ugcaagacug uaucaagaau aucgaucgcu augcccugga cgaucucaaa      720

aguaaggcgc uguucaacgu cuuggccgca ccgacuuacg acauuaccga auaucugagg      780

gccacuaaag agaagcccga aaacacccca ugguacggca agaucgaugg cuucauuaau      840

gagcucaaaa agcuggcacu guaugggaaa aucaacgaca auaacuccug gauuaucgac      900

aaugguaucu accacauugc ccccuugggc aagcuccaua gcaacaauaa aaucgggauu      960

gaaacccuga cugaggugau gaagguauau ccauaccugu ccaugcagca ccuccagagu     1020

gccgaucaga ucaagcggca uuacgacagc aaagaugcgg agggcaacaa gauuccccug     1080

gacaaauuua agaaagaagg uaaggagaag uauugcccga aaacguacac cuucgaugac     1140

gggaagguga ucaucaaagc aggcgcccgc gucgaagagg aaaaggugaa aagguuguau     1200

ugggccucca aggaggugaa uagccaauuu uuccgggucu acggcauuga uaaaccccug     1260

gaggaaggga acccagacga uauccucacu auggugauuu auaauagucc cgaggaauac     1320

aagcugaacu ccguacugua ugguuacgac accaauaacg gcgggaugua caucgagcca     1380

gaaggcaccu uuuucacuua ugagcgcgag gcacaggaaa gcacguacac cuuggaggaa     1440

cucuuuaggc acgaguauac ucacuaccug cagggucggu augccgugcc cggccagugg     1500

gggaggacca agcuguacga uaaugaccgc cucaccuggu augaggaagg cggggcggag     1560

cuguucgccg guaguacucg gacguccggc auuuugccaa ggaaaagcau cgucagcaac     1620

auucauaaca ccacucgcaa uaaccgguac aagcuguccg acaccgugca caguaaauac     1680

ggggcgagcu uugaguucua uaauuacgcc uguauguuua uggauuauau guacaacaag     1740

gacaugggca uccucaauaa acugaacgau cuggcaaaga auaacgacgu cgaugguuau     1800

gacaauuaca ucagggauuu guccagcaac uaugcccuga augacaagua ccaagaucau     1860

augcaggaac gcauugacaa cuacgaaaau cucacugugc cguucguggc cgaugacuau     1920

cugguacggc acgcauacaa aaaccccaau gagaucuaua gugagauuuc cgaaguggcc     1980

aagcucaaag augcaaagag cgaggucaaa aagucccagu acuuuaguac cuucacgcug     2040

aggggcagcu auaccggggg cgccuccaag gggaaauugg aagaccaaaa ggcaaugaac     2100

aaauucaucg acgauagccu gaagaaacuc gacacuuaca guugguccgg cuacaagacc     2160

cugacugccu auuuuaccaa cuacaaagug gauagcucca aucgggucac guaugacgug     2220

guguuccacg guuaccugcc aaacgagggg gauaguaaga auagcuugcc cuauggcaag     2280

auuaacggua ccuacaaagg cacugaaaag gagaaaauca aguuuuccag cgaggggagu     2340

uucgacccag auggcaaaau cguauccuau gaaugggacu uuggggaugg caauaagagc     2400

aacgaggaaa aucccgagca uuccuacgac aaggugggua ccuacacugu caaacugaag     2460

gugaccgaug acaaagggga aagcaguguc agcacgacca cugccgagau uaaggaccuc     2520

uccgagaaca aacugccggu gaucuauaug cacgugccaa agaguggcgc acucaaucag     2580

aagguagucu ucuacggcaa agggaccuau gaucccgacg guagcauugc gggcuaccag     2640

ugggauuuug gggacggcuc cgauuucagc uccgaacaga accccaguca uguguauacu     2700

aagaaaggug aguacaccgu gacgcugcgc gucauggaca gcuccgggca aaugagugaa     2760

aagaccauga aaaucaagau uacugaucca guguauccca ucggcaccga gaaagagcca     2820

aauaacagca aggaaacugc cuccggcccg aucgugcccg ggauuccagu aagcgguacc     2880

aucgagaaua ccagugacca ggauuacuuu uacuucgacg ucauuacucc cggcgaagug     2940

aagaucgaua uuaacaaauu gggguauggc ggugcaacgu ggguggucua cgacgagaau     3000

aacaacgccg uguccuaugc caccgaugac gggcagaauc ugagcggcaa guuuaaagca     3060

gacaagccag gcagguacua uauccaccug uacauguuca acggguccua uaugcccuac     3120

cggauuaaua ucgaagguag cguaggccgc ugaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  2044
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt7)

<400>  2044
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggcagccuuu       60

gcgaugcccu ugccaccgca ccccggucau ccaggcuaca uuaacuucag cuaugaggug      120

cugacucccc ucaaguggua ccaguccauc aggccacccu auccaaguua cggguaugaa      180

ccgaugggcg guuggcugca ccaucaaauu auccccgucu ugagccagca gcacccaccc      240

acccauacgc ugcagccaca ccaccauauu cccgugguac cggcccaaca gcccgugauc      300

ccacagcagc ccaugaugcc aguccccggg caacacucca ugacuccaau ccagcaucac      360

cagccgaauc ugcccccacc cgcacagcaa ccauaccagc cccagccggu gcaaccacag      420

ccccaccagc ccaugcagcc acaaccccca gugcauccga ugcagccccu cccaccccag      480

ccaccccugc cgccaauguu ucccaugcag ccacugcccc cgaugcuccc cgacuugacc      540

cuggaggccu ggccaaguac cgauaaaacu aagcgggaag aggucgacug aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  2045
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt7)

<400>  2045
gggagaaagc uuaccaugcc ccugccaccg caccccggcc auccagggua caucaacuuc       60

agcuaugagg ugcucacccc acugaagugg uaccagucca uuaggccacc cuaucccagu      120

uacgguuaug aaccgauggg cgggugguga ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  2046
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt7)

<400>  2046
gggagaaagc uuaccaugcc ccugccaccg caccccggcc auccagggua caucaacuuc       60

agcuaugagg ugcucacucc ccugaagugg uaccagucca uuaggccacc cccaauguug      120

ccggaccuga cccucgaagc cuggcccagu accgauaaaa cgaagcggga ggaagucgac      180

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  2047
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt7)

<400>  2047
gggagaaagc uuaccauggc cgugauggca cccaggaccc ugguccuccu guugagcggc       60

gcccuggcgc ucacucagac cugggccaug ccacugccgc cccacccagg gcaucccggu      120

uacaucaacu ucuccuauga gguguugacg ccacugaagu gguaccaaag uauucggccc      180

ccauauccga gcuacggcua ugaacccaug ggcggguggu gaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  2048
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt7)

<400>  2048
gggagaaagc uuaccauggc cgugauggca cccaggaccc ugguccuccu guugagcggc       60

gcccuggcgc ucacucagac cugggccaug ccacugccgc cccacccagg gcaucccggu      120

uacaucaacu ucuccuauga gguguugacg ccacugaagu gguaccaaag uauucggccc      180

ccaccgaugc uccccgaccu gacucuggaa gcauggccaa gcaccgauaa aaccaagcgc      240

gaggaaguag acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  2049
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt7)

<400>  2049
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccucguggg ggcagccuuu       60

gcgaugcccc ugccaccgca ccccggucau ccaggcuaca uuaacuucag cuaugagguc      120

uugacucccc ugaaguggua ccaguccaug aucaggccac ccuauaguag cuacggguau      180

gaaccaaugg gcgguuggcu ccaccaucaa auuaucccgg ugguauccca gcagcacccc      240

cugacccaua cguugcagag ucaccaccau auuccagugg uccccgccca acagccacgg      300

gugcgccagc aggcacugau gcccgugccg gggcaacaga gcaugacucc cacccagcac      360

caucagccaa aucucccccu gccagcccaa cagcccuuuc agccacaacc gguccagccc      420

cagccacacc agcccaugca accacagccc ccggugcagc caaugcagcc ccugcucccc      480

caaccacccc ugccaccgau guuccccuug aggccacugc ccccaauccu ccccgaccug      540

caccuggagg cauggccggc caccgauaaa acuaagcagg aagagguaga cugaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  2050
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt7)

<400>  2050
gggagaaagc uuaccaugcc ccugccaccg caccccggcc auccagggua caucaacuuc       60

agcuaugagg ugcucacccc acugaagugg uaccagucca ugauuaggcc acccuauagu      120

agcuacgguu augaacccau gggcgggugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  2051
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt7)

<400>  2051
gggagaaagc uuaccaugcc ccugccaccg caccccggcc auccagggua caucaacuuc       60

agcuaugagg ugcucacucc ccugaagugg uaccagucca ugauuaggcc acccccaauc      120

uugccggacc ugcaccucga agccuggccc gcaaccgaua aaaccaagca agaggaaguc      180

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  2052
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt7)

<400>  2052
gggagaaagc uuaccauggc cgugauggca cccaggaccc ugguccuccu guugagcggc       60

gcccuggcgc ucacucagac cugggccaug ccacugccgc cccacccagg gcaucccggu      120

uacaucaacu ucuccuauga gguguugacg ccacugaagu gguaccaaag uaugauucgg      180

cccccauaua gcuccuacgg cuaugaaccg augggcgggu ggugaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  2053
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt7)

<400>  2053
gggagaaagc uuaccauggc cgugauggca cccaggaccc ugguccuccu guugagcggc       60

gcccuggcgc ucacucagac cugggccaug ccacugccgc cccacccagg gcaucccggu      120

uacaucaacu ucuccuauga gguguugacg ccacugaagu gguaccaaag uaugauucgg      180

cccccaccga uccuccccga ccugcaccug gaagcauggc cagccacuga uaaaaccaag      240

caggaggaag uagacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  2054
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt7)

<400>  2054
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggcagccuuu       60

agcaugcccu ugccaccgca ccccggucau ccaggcuaca uuaacuucuc cuaugaggug      120

cugacucccc ucaaguggua ccagaauaug aucaggcacc cauauaccag uuacggguau      180

gaacccaugg gcgguuggcu gcaucaccaa auuaucccag ucgugagcca gcagacgccg      240

cagucccaug cguugcaacc ccaccaccau auuccaaugg uacccgccca gcagccaggg      300

aucccccagc aaccgaugau gccccugcca ggccagcaca guaugacucc cacccagcau      360

caccagccaa accucccccu gccagcacaa cagccguuuc agccccaacc agugcagccc      420

cagccacacc agccccugca accgcagagc ccaaugcauc ccauccagcc ccuccugcca      480

cagcccccau ugccgcccau guucuccaug caaagccugc ucccagaccu gccccuggag      540

gccuggccag caaccgauaa aacuaagcgg gaagaggucg acugaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  2055
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt7)

<400>  2055
gggagaaagc uuaccaugcc ccugccaccg caccccggcc auccagggua caucaacuuc       60

agcuaugagg ugcucacucc ccugaagugg uaccagaaua ugauuaggca cccauauacc      120

uccuacgguu augaacccau gggcgggugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  2056
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt7)

<400>  2056
gggagaaagc uuaccaugcc ccugccaccg caccccggcc auccagggua caucaacuuc       60

agcuaugagg ugcucacucc ccugaagugg uaccagaaua ugauuaggca cccauccuug      120

cugcccgacc ucccacugga agccuggccg gcaaccgaua aaaccaagcg ggaggaaguc      180

gacugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  2057
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt7)

<400>  2057
gggagaaagc uuaccauggc cgugauggca cccaggacuc ugguccuccu guugagcggc       60

gcccuggcgc ucacucagac cugggccaug ccacugccgc cccacccagg gcaucccggu      120

uacaucaacu ucuccuauga gguguugacg ccacugaagu gguaccaaaa uaugauucgg      180

caccccuaua ccaguuacgg cuaugaacca augggcgggu ggugaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  2058
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt7)

<400>  2058
gggagaaagc uuaccauggc cgugauggca cccaggaccc ugguccuccu guugagcggc       60

gcccuggcgc ucacucagac cugggccaug ccacugccgc cccacccagg gcaucccggu      120

uacaucaacu ucuccuauga gguguugacg ccacugaagu gguaccaaaa uaugauucgg      180

caccccaguc uccugccaga ccugccgcuc gaagcauggc ccgccacuga uaaaaccaag      240

cgcgaggaag uagacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  2059
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt7)

<400>  2059
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggcagccuuu       60

agcaugcccu ugccaccgca ccccggucau ccaggcuaca uuaacuucuc cuauaucagg      120

caccccuaca ccaguuaugg guacgagcca augggcgguu ggcugcauca ccagauuauc      180

cccgugguca gccaacagac uccacagucc caugcgcucc agccgcacca ccauauuccc      240

auggugccag cccaacagcc cgggauccca cagcagccca ugaugccgcu gcccggccaa      300

cacaguauga cgccaacuca gcaucaccag cccaauuugc cacugcccgc acagcaacca      360

uuucagccgc agcccguaca accacagccc caccagccac uccagcccca aagcccgaug      420

cauccaaucc agccccugcu gccccagcca ccccucccac cgauguucuc caugcagagc      480

cuguugcccg accugccacu cgaagccugg cccgcaaccg auaagaccaa acgggaggaa      540

guggacugag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  2060
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt7)

<400>  2060
gggagaaagc uuaccauggg caccuggauc uucuuugccu gccugcucgg ggcaagccug       60

gccaugcccu ugccaccgca ccccggucau ccaggcuaca uuaacuucuc cuaugaggug      120

cugacucccc ucaaguggua ccagaauaug aucaggcacc cauauaccag uuacggguau      180

gaacccaugg gcgguuggcu gcaucaccaa auuaucccag ucgugagcca gcagacgccg      240

cagucccaug cguugcaacc ccaccaccau auuccaaugg uacccgccca gcagccaggg      300

aucccccagc aaccgaugau gccccugcca ggccagcaca guaugacucc cacccagcau      360

caccagccaa accucccccu gccagcacaa cagccguuuc agccccaacc agugcagccc      420

cagccacacc agccccugca accgcagagc ccaaugcauc ccauccagcc ccuccugcca      480

cagcccccau ugccgcccau guucuccaug caaagccugc ucccagaccu gccccuggag      540

gccuggccag caaccgauaa aacuaagcgg gaagaggucg acugaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  2061
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt7)

<400>  2061
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggcagccuuu       60

agcaugcccu ugccaccgca ccccggucau ccaggcuaca uuaacuucuc cuaugaggug      120

cugacucccc ucaaguggua ccagaauaug aucaggcacc caagucuguu gcccgaccug      180

ccacucgaag cguggccggc caccgauaaa acgaagcggg aggaagucga cugaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  2062
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt7)

<400>  2062
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggcagccuuu       60

agcaugcccu ugccaccgca ccccggucau ccaggcuaca uuaacuucuc cuaugaggac      120

cuguaccucg aagcgaucag gauugaucgg acugccuuug ugcugacccc cuugaagugg      180

uaucagaaua ugauccgcca cccauacacg aguuaugggu acgagcccau gggcgguugg      240

cugcaucacc aaauuauccc agucgugagc cagcagacuc cgcaguccca ugcacuccaa      300

ccccaccacc auaucccaau gguacccgcc cagcagccag ggauucccca gcaaccgaug      360

augccccugc caggccagca caguaugacc cccacccagc aucaccagcc aaaccugccc      420

cucccagcac aacagccguu ccagccccaa ccagugcagc cccagccaca ccagccccug      480

caaccgcaga gcccaaugca ucccauccag cccuugcugc cacagccccc acucccgccc      540

auguuuucca ugcaaagccu gcugccagac uugccccucg aagccuggcc agcgacugau      600

aaaaccaaga gggaggaagu cgacugagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  2063
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt7)

<400>  2063
gggagaaagc uuaccauggg caccuggauc cuguucgccu gccuccuggg ggcagccuuu       60

agcaugcccu ugccaccgca ccccggucau ccaggcuaca uuaacuucuc cuaugaggug      120

cugacucccc ucaaguggua ccagaauaug aucaggcacc caacgcccca aagucaugcg      180

cugcagccac accaucacau uccgaugguc cccgcccagc agccagggau cccccaacag      240

ccaaugaugc ccuugccggg ccagcacagc augaccccca cucagcauca ccaaccaaac      300

cugccccucc cagcacagca gcccuuucag ccacaaccgg ugcagcccca gccacaucaa      360

ccccugcagc cacagucccc caugcacccg auucagccac ugcuccccca acccccacug      420

cccccaaugu ucaguaugca gagcuugcug ccggaccucc cccuggaagc cuggccagca      480

accgauaaaa ccaagcggga ggaaguagac ugaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  2064
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt7)

<400>  2064
gggagaaagc uuaccaugcc ccugccaccg caccccggcc auccagggua caucaacuuc       60

agcuaugagg ugcucacucc ccugaagugg uaccagaaua ugauuaggca cccauauacc      120

uccuacgguu augaacccau gggcgggugg uugcaucacc aaaucauucc agucgugagu      180

cagcagaccc cgcagagcca ugcccugcaa ccccaccacc auaucccaau gguacccgca      240

cagcagccag gcauucccca gcaaccgaug augccccucc caggucagca cuccaugacg      300

cccacucagc aucaccagcc aaaccugccc uugccagccc aacagccguu ucagccccaa      360

ccagugcagc cccagccaca ccagccccug caaccgcaga guccaaugca ucccauccag      420

ccccuccugc cacagccccc acugccgccc auguucagca ugcaaucccu ccugccagac      480

uugccccugg aggcguggcc agccaccgau aaaaccaagc gggaagaggu cgacugagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  2065
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt7)

<400>  2065
gggagaaagc uuaccaugcc cggcguggcc aggcugccac uccuguuggg gcugcuccug       60

uugccgcggc ccggucgccc acuggaccuc gcagauuaca ccuaugaccu ggccgaggaa      120

gaugacagcg agccccugaa cuacaaggau ccaugcaaag cggccgcauu ccucggcgac      180

aucgcccugg augaagagga cuugagggca uuucaggucc aacaggccgu ggaucugcgg      240

cgccacacug cgaggaaguc caguauuaaa gccgcaguac ccgggaauac cagcacgcca      300

uccugucaga guacuaacgg ccagccgcaa cggggugccu gcgggcgcug gaggggccgg      360

agccgcucca ggcgggccgc aaccagccgc cccgaaaggg uguggccaga cggcgucauc      420

cccuucguga uuggggguaa uuuuaccggc ucccagcggg ccguguuccg ccaggcgaug      480

aggcauuggg agaagcacac uugugucacc uuucucgagc ggacggauga agacaguuau      540

aucguguuca cuuaccgccc augcgggugu ugcagcuaug uaggcaggcg gggugggggc      600

ccccaggcca uuuccaucgg caaaaacugu gauaaguuug ggaucguggu ccaugagcug      660

ggucacgugg ugggcuucug gcaugaacac accaggccgg accgcgaccg gcacgucagc      720

auugugaggg agaauaucca acccgggcag gaguacaacu uucugaagau ggaaccacag      780

gagguagaaa guuugggcga gacuuaugau uucgacucca uuaugcauua cgcacgcaau      840

accuuuagcc gggguaucuu ccucgauacc auugugccca aauacgaagu caacggcgug      900

aagccaccca ucgggcagag gacgcgccug uccaaaggcg acauugccca agcacggaag      960

cuguauaaau gcccagccug uggggagacu cuccaggaua guaccgguaa uuucagcucc     1020

ccggaguacc ccaacggcua uagcgcccac augcauugcg uguggaggau cagugucacu     1080

ccaggggaaa agaucauucu gaauuuuacc uccuuggacc uguaccggag ccgccucugc     1140

ugguaugauu acguggaggu aagggacggc uucuggcgga aagcgccccu gcgcgguagg     1200

uuuuguggca guaagcugcc agaacccauc guguccaccg auagccgguu gugggucgag     1260

uuccgcagcu ccaguaacug gguggggaag ggcuuuuucg cagucuauga agccauuugc     1320

gggggcgacg ugaaaaagga uuacggucac auccagagcc cgaauuaccc agacgacuau     1380

aggcccucca aaguguguau uuggcggauc caaguaagcg agggguuuca cgugggccuc     1440

acuuuccaga guuuugagau cgaaaggcau gauuccugcg ccuacgacua ucuggagguc     1500

cgcgaugguc acagcgaauc caguacgcug auuggccggu acugugggua ugagaagccc     1560

gacgauauca aaagcaccuc cagcaggcuc uggcugaagu ucgugaguga cggcuccauu     1620

aacaaggcag gguuugccgu caauuucuuu aaagaagugg augagugcag ccgcccaaac     1680

cggggcgguu gugagcagag gugcuugaac acucuggggu ccuacaagug uaguugcgac     1740

cccggcuaug aacucgcgcc agauaaacgc cggugcgagg ccgcaugugg cggguuccug     1800

accaagcuga augguagcau caccuccccg ggcuggccca aagaauaccc acccaacaag     1860

aauugcauuu ggcaguuggu ggccccaacu caauacagga ucagccucca guucgacuuu     1920

uucgagacgg aggggaacga uguauguaag uaugacuuug uggaaguccg caguggccug     1980

accgcagauu ccaaacugca ugguaaguuc ugcgggagcg agaaacccga agugaucacu     2040

ucccaguaca auaacaugcg ggucgaguuu aagagcgaca auaccgugag uaaaaagggc     2100

uucaaggccc acuuuuucag cgacaaagau gaauguucca aggacaacgg cgggugccag     2160

caagauugug ugaauaccuu ugguaguuau gagugccagu guaggagcgg cuucguacuc     2220

caugacaaca aacacgauug caaggaggcc gggugugacc acaaagucac uuccacgagc     2280

ggcaccauua cuuccccgaa uuggccagau aaguacccca guaaaaagga augcaccugg     2340

gcaaucagcu ccacuccagg ucaucgcgug aagcugaccu uuauggagau ggacauugaa     2400

agucagcccg agugcgccua ugaucacuug gaaguguucg acgggcggga ugcgaaagcc     2460

ccgguccugg gcagguucug uggcagcaag aaacccgagc cagugcucgc aacggggucc     2520

cgcauguuuc ugcgguucua cagcgacaac agugugcaga ggaaggguuu ucaagccucc     2580

caugccaccg agugcggcgg gcagguacgc gcagacguca aaacuaagga ucuguauagc     2640

cacgcgcagu ucggcgacaa uaacuacccc gguggggugg auugugaaug ggugaucguc     2700

gccgaggaag gcuacggcgu ggaguuggua uuucagaccu ucgaagugga ggaggaaacu     2760

gacugcgggu augauuacau ggagcuguuu gacgguuaug auuccaccgc accaaggcuc     2820

ggccgguacu gugggagcgg ucccccagaa gaggucuaua gugccggcga cuccgugcug     2880

gugaaguucc acagcgauga cacgauuacc aaaaagggcu uucaucucag guacaccagu     2940

acuaaauucc aagauacucu gcacucccgc aagugaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  2066
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt7)

<400>  2066
gggagaaagc uuaccauggu ggccggcacc aggugccugc ucgcacuguu gcugccccag       60

guccuccugg guggggccgc gggcuuggug ccagagcugg ggcggcgcaa guucgccgca      120

gccagcuccg gcaggccgag uagccaaccc uccgacgaag uacucaguga guuugaacug      180

cggcugcuca gcauguucgg ucugaaacag cgcccaacuc ccuccaggga ugcagugguc      240

ccacccuaca uguuggaccu guaucggcgc cacagcgggc agccaggcuc cccggccccc      300

gaucauaggc ucgagcgggc ggccagucgc gcaaacaccg ugaggagcuu ucaccaugaa      360

gagucccugg aggaacugcc agagacgagc ggcaagacua cccggcgcuu cuuuuucaau      420

uugaguucca uccccaccga agaguuuauu acuagcgccg agcuccaggu guucagggaa      480

caaaugcagg acgcccuggg gaacaauucc aguuuucacc aucggaucaa cauuuacgag      540

aucauuaaac cagcaaccgc caauagcaag uuccccguca cgcgccugcu cgauacuagg      600

cuggugaacc agaaugcguc ccggugggaa uccuuugacg uaaccccggc cgugaugcgc      660

uggacugcac agggucacgc caaccacggc uucgucgugg agguggcaca uuuggaagag      720

aaacaagggg ucaguaagag gcacgugcgg aucuccagga gccugcauca ggaugagcac      780

aguugguccc agauccgccc ccuccuggua accuucggcc acgacgguaa ggggcaucca      840

cugcacaaac gggaaaagag gcaggccaaa cauaagcaac gcaaacggcu caagagcagc      900

uguaaaaggc accccuugua uguggauuuu uccgacgucg gcuggaauga uuggauugug      960

gccccacccg gcuaccaugc guucuauugc cacggggagu guccauuucc gcuggcagac     1020

caccugaaca guaccaauca ugccaucgug cagacgcucg ucaacagcgu gaauagcaag     1080

auucccaagg ccugcugugu accaacugaa cugagcgcaa ucaguauguu guaccuggau     1140

gagaacgaaa aagugguccu caagaauuau caggacaugg uggucgaggg uugcggcugu     1200

cgcugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  2067
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt7)

<400>  2067
gggagaaagc uuaccaugau ccccggcaac aggaugcuga uggugguccu ccugugccag       60

guguugcucg ggggugccag ccacgcaucc cugauuccag agaccggcaa gaaaaaggua      120

gccgaaaucc aagggcaugc gggcggucgg cgcagugggc agagccacga gcuguugagg      180

gacuucgaag ccacucugcu ccagauguuu ggccugcggc gcaggccgca gcccuccaaa      240

agugcaguga uuccagauua caugcgggac cuguaucgcc uccaaagcgg cgaggaagag      300

gaggaacaga uccauuccac cgggcuggag uaccccgaaa ggccagccag ccgggcaaau      360

acgguccgcu ccuuccacca ugaggagcac uuggaaaaca uucccgguac cagugagaau      420

agcgccuuua gguuccuguu uaaccucucc agcaucccag aaaaugaggu gaucaguucc      480

gcggaacugc ggcuguuccg cgaacaggug gaucagggcc cggacuggga gaggggguuu      540

caccggauua acaucuauga ggucaugaag cccccagccg aggugguacc cggccauuug      600

auuacucgcc uccuggauac caggcuggug caccauaaug ucacucggug ggaaaccuuc      660

gacgugagcc cagcagugcu ccgcuggacg agggagaaac aacccaacua cggucuggcc      720

aucgaaguca cucacuugca ccagacccgg acucaucagg ggcagcacgu gaggauuucc      780

cgcagucugc cgcaaggcag cggcaauugg gcccagcucc ggccccugcu gguaaccuuu      840

gggcaugaug guaggggcca cgcauugacc cgccggaggc gcgccaagcg guccccaaag      900

caucacagcc agagggcgcg gaaaaagaac aaaaauuguc gcaggcacag ucucuaugug      960

gacuucuccg augucgggug gaacgacugg aucguggcac ccccaggcua ccaagccuuu     1020

uauugccaug gugauugucc cuucccacug gccgaccacc ugaauagcac gaaccaugca     1080

auugugcaga cucucgucaa uagugugaac uccagcaucc cgaaggccug cuguguaccc     1140

accgagcuga gcgccaucuc cauguuguac cuggaugagu acgacaaagu gguccucaag     1200

aacuaucagg aaaugguggu cgagggcugc gggugucggu gaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  2068
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt7)

<400>  2068
gggagaaagc uuaccaugcc cggccugggg aggcgggccc aguggcucug cugguggugg       60

ggucuguugu guagcugcug uggcccaccg ccccugcgcc caccccuccc agcagccgcg      120

gccgcagccg cagggggcca acuguugggu gacgggggcu cccccggcag gaccgagcag      180

ccaccgccca guccacagag cuccaguggg uuccuguacc ggcgccucaa gacucaggag      240

aaaagggaaa ugcaaaagga aauccugagc gugcuggguc ucccccaccg gccacgcccc      300

cugcauggcu ugcagcagcc gcagccccca gcccugaggc aacaggagga acagcagcaa      360

cagcagcaac ucccccgcgg ggagccaccc ccaggccggc ugaaauccgc gccgcuguuu      420

auguuggauc ucuauaacgc ccugagcgca gacaaugaug aggacggugc cuccgaaggg      480

gagaggcagc agaguuggcc ccacgaagcc gcaagcucca gccagcggcg ccaaccaccc      540

ccaggcgccg cgcauccccu gaacaggaag agucuccugg ccccgggcuc cgggagcggu      600

ggcgcauccc cauugaccag ugcccaggau agcgcauucc ugaaugacgc cgauaugguc      660

auguccuuug ugaaccucgu agaguacgac aaagaguuca gcccccggca gcgccaccau      720

aaggaauuua aguucaaucu gagucagauu cccgaggggg aaguggucac ggccgcggag      780

uuuaggaucu auaaagauug cgugaugggc uccuucaaga accaaacuuu ucugauuagc      840

aucuaccagg uguugcagga acaccagcac cgggacagug aucucuuccu gcuggacacc      900

cgcgucgugu gggcauccga ggaggguugg cucgaauuug auauuaccgc cacuagcaau      960

cuguggguag ugaccccaca acauaacaug ggcuugcagc ugagcgucgu gacgagggac     1020

ggggugcacg uccauccccg ggccgcaggc cucgugggga gggacggucc auaugauaaa     1080

cagccguuca ugguagccuu cuuuaaggug uccgaggucc acgugcgcac uacccggagu     1140

gcgagcucca ggcgccggca gcaaagcagg aaucgcagua cucaguccca ggacguggcc     1200

cgggucagcu ccgcaaguga uuacaacagc uccgaacuga aaaccgccug uaggaagcac     1260

gagcuguaug ugagcuucca agacuugggc uggcaggauu ggaucaucgc acccaaaggg     1320

uacgccgcca auuacugcga cggcgaaugu aguuuuccac ucaacgcaca uaugaaugcc     1380

accaaccacg cgauuguaca gacgcuggug caucugauga aucccgagua ugucccaaag     1440

cccugcugug ccccgacuaa gcucaacgca aucuccgugc uguacuucga ugacaacagc     1500

aaugucauuu ugaaaaagua ucggaacaug guggugcgcg ccugcgguug ccacugagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  2069
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt7)

<400>  2069
gggagaaagc uuaccaugca cgugaggagc cugcgggccg cagcgcccca uuccuucguc       60

gcccucuggg ccccacuguu uuugcugcgc agugcacucg ccgacuucag ccuggauaac      120

gaggugcacu ccaguuuuau ccauaggcgg uugcgcagcc aggaaaggcg ggagaugcaa      180

cgcgaaauuc uguccauccu cggccugccg cacaggcccc ggccacaucu gcaggggaag      240

cacaauagcg cacccauguu caugcucgac cuguacaacg ccauggcggu agaggaaggu      300

ggcgggccag gcggucaggg guuuuccuau cccuacaaag ccguguucag uacccagggc      360

ccaccguugg caagccugca agauucccac uuucucacug acgccgauau ggucaugagc      420

uucgugaauc ugguggagca ugacaaggag uuuuuccacc cccgcuauca ucacagggaa      480

uuucgguucg aucugaguaa aauuccagag ggcgaagccg ucaccgcagc cgaguuccgc      540

aucuacaagg acuauauuag ggagcgguuu gauaacgaaa cguuccgcau cuccguguac      600

cagguauugc aggagcaccu cgggagggaa agcgaccugu uucugcucga uucccggacu      660

cugugggcga gugaggaagg uugguuggug uucgacauca ccgccaccag caaucauugg      720

gucgugaacc cccgccacaa ucugggccuc cagcuguccg uggagacucu ggaugggcaa      780

agcauuaacc caaaauuggc aggccucauc gguaggcaug ggccccagaa uaagcagccg      840

uuuauggucg ccuucuuuaa ggcaaccgag gugcacuucc ggaguauuag guccacgggc      900

agcaaacagc gcagucaaaa ccgguccaag acucccaaaa aucaggaagc ccugaggaug      960

gccaacguag cggagaauag cagcuccgac cagcgccaag caugcaagaa acaugaacug     1020

uaugugaguu uucgggaccu cggcuggcag gauuggauca uugccccaga gggguacgcc     1080

gcauacuauu gugaagguga gugcgccuuc ccccugaaca gcuacaugaa ugcgaccaac     1140

cacgccaucg uccagacuuu ggugcacuuu auuaacccag agaccgugcc caagccaugu     1200

ugcgcaccga cccagcugaa ugccaucucc guccucuauu ucgacgauag caguaacgug     1260

auccugaaaa aguacaggaa uaugguagug cgcgcaugug gcugccauug aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  2070
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt7)

<400>  2070
gggagaaagc uuaccaugaa ggccagcgca gcccugcucu gccuguugcu gaccgcggcc       60

gcauucaguc cccagggccu cgcccaacca guggggauca acacuuccac cacguguugc      120

uacagguuua uuaauaaaaa gaucccgaaa cagcggcugg agagcuaucg caggacuacc      180

uccagucacu guccccggga agcagucauu uucaagacca aauuggacaa ggagaucugc      240

gccgauccaa cucagaagug ggugcaggac uuuaugaaac aucuggauaa gaaaacccaa      300

acgcccaagc ucugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  2071
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt7)

<400>  2071
gggagaaagc uuaccaugcu gcucacccug aucauuuugc ugcccguggu cagcaaguuc       60

uccuuuguga gucucagcgc cccacagcac ugguccugcc cggagggcac ucuggcaggg      120

aacgguaaua guaccugugu aggccccgcc ccauucuuga ucuuuagcca ugggaacucc      180

auuuucagga ucgacacgga aggcacuaau uacgagcaac ugguggucga cgcgggugug      240

agcgugauua uggacuuuca cuauaacgaa aaacggaucu acugggucga ucucgagcgc      300

cagcugcugc agaggguguu ccucaauggg ucccggcagg aacgcguaug caacaucgag      360

aagaauguga guggcauggc cauuaacugg aucaaugagg aagucauuug gagcaaccaa      420

caggagggca ucauuaccgu gaccgacaug aaagggaaua acucccauau ccuguugagc      480

gcacugaagu aucccgccaa uguggcaguc gauccagugg aaagguuuau uuucuggagu      540

uccgagguag ccgguagccu cuaccgggcg gaccuggaug gcgugggggu caaagcccug      600

uuggagacuu ccgaaaagau caccgcagug agucucgacg ugcuggauaa gcgccuguuu      660

uggauccagu auaacaggga gggcagcaau ucccucauuu guagcugcga cuacgauggu      720

gggagugucc acaucuccaa acaucccacg cagcacaacc uguucgccau gagcuuguuu      780

ggcgaccgga uuuucuauag uacuuggaag augaaaacca ucuggauugc caacaagcac      840

acuggcaaag auauggugcg caucaaucug cauuccagcu ucguaccacu cggggaacug      900

aagguggucc acccgcuggc acaacccaaa gccgaggacg acaccuggga accagagcag      960

aaguugugua agcucaggaa agguaacugc agcuccaccg uguguggcca ggaucugcag     1020

agucaucugu gcaugugugc ggagggguac gcccucagcc gggaccgcaa guacugcgaa     1080

gaugucaaug agugcgcauu uuggaaccac ggcuguacgc uggguugcaa aaauacuccc     1140

ggcuccuauu acuguaccug cccagugggg uucguguugc ugcccgacgg caagaggugu     1200

caccaacucg uaagcugccc gcggaacgug agugaauguu cccaugauug cguccugacu     1260

agcgaggggc cccuguguuu uugcccagaa gguuccgugu uggagcgcga cggcaaaacc     1320

ugcagugggu guagcucccc cgauaauggc gguugcagcc agcucugugu cccacugagu     1380

cccguguccu gggagugcga cuguuuccca ggcuaugauc ugcagcucga cgaaaagagc     1440

ugcgccgcau ccgggccgca acccuuucug uuguucgcca acagucagga uaucaggcac     1500

augcauuuug acggcaccga cuacgggacu cugcucagcc agcagauggg caugguguau     1560

gcccuggauc acgacccagu agagaauaag auuuacuucg cgcauacggc acugaaaugg     1620

aucgaacggg ccaacaugga ugguucccaa cgcgagaggu ugauugaaga ggggguggac     1680

guccccgagg gccuggccgu ggauuggauc ggucggaggu uuuauuggac cgaccgcggc     1740

aagagccuca uugggcggag ugaucugaau ggcaaaaggu ccaagaucau cacuaaagaa     1800

aacauuagcc agccacgcgg gaucgcaguc caccccaugg ccaagcggcu guucuggacc     1860

gacaccggca uuaauccgag gaucgagucc agcagucucc aggguuuggg gcgccuggug     1920

auugcgagcu ccgaucucau cuggccaagu ggcauuacua ucgacuuucu gacggauaag     1980

cuguacuggu gugacgccaa acagagcgug aucgaaaugg caaacuugga uggcuccaag     2040

cggaggcggc ugacccaaaa ugacguaggg caccccuucg ccgucgcagu guuugaggac     2100

uacguguggu ucagcgauug ggccaugccc uccgucaugc gcgugaacaa aaggacuggu     2160

aaggaccggg ugcgccucca gggcaguaug cugaaaccaa gcucccucgu agucgugcau     2220

ccccuggcca agccaggggc agauccgugc uuguaucaga acggcgguug ugagcacauu     2280

ugcaagaaaa ggcuggggac cgccuggugu aguugccggg aaggcuucau gaaggcgagc     2340

gacggcaaaa ccugccuggc ccucgauggg caucagcugu uggccggugg cgagguggac     2400

cugaagaauc aagucacucc ccucgauauc cuguccaaaa cgcgcgugag cgaagacaac     2460

auuaccgaga gucagcacau gcucguagca gaaaucaugg uguccgauca ggacgauugu     2520

gccccagucg ggugcagcau guacgcaagg uguauuuccg agggcgagga cgcgacuugc     2580

cagugucuga aggguuuugc cggggacggc aaauugugca gcgauaucga cgaaugugag     2640

augggcgugc ccgugugccc acccgcaagu uccaagugua ucaauaccga aggggguuau     2700

gucugccggu gcagcgaggg cuaccaaggg gauggcauuc acugucugga caucgaugaa     2760

ugccagcugg gugagcauag uuguggggag aacgccuccu gcacuaauac cgaaggcggc     2820

uauacgugua ugugcgccgg gaggcucagc gagccggguc ugauuugucc agacuccacu     2880

cccccacccc acuugcgcga agaugaccau cacuacagcg ugcggaacag ugauagcgag     2940

ugcccgcugu cccaugacgg cuauugucuc cacgaugggg uaugcaugua caucgaagca     3000

cuggacaagu acgccugcaa uugugugguc ggcuauauug gugagaggug ccaguaccgc     3060

gaucugaaau ggugggagcu ccggcacgcg ggccaugggc aacagcagaa ggugaucgug     3120

gucgccgugu guguaguggu ccuggugaug uugcugcucc ugaguuugug gggcgcacac     3180

uauuacagga cccagaaacu gcucagcaag aaccccaaaa auccauauga agaguccagc     3240

cgcgacgugc gguccaggcg ccccgccgac accgaagaug ggaugaguag cugcccacaa     3300

cccugguucg ucgugaucaa ggagcaucag gaccugaaga acgguggcca gccaguagcc     3360

ggggaggaug gccaggcagc cgacgguucc augcaaccga cuagcuggcg gcaggaaccc     3420

cagcugugug gcauggggac cgagcagggc ugcuggauuc cagugaguuc cgauaaaggg     3480

agcugucccc aagucaugga aagguccuuu cacaugccaa guuacgguac gcagacccuc     3540

gagggcgggg uggaaaagcc ccacagccug uuguccgcga auccgcugug gcagcaacgc     3600

gcccucgauc ccccacauca gauggagcug acucagugag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  2072
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt7)

<400>  2072
gggagaaagc uuaccaugac cgccggcagg cggauggaga ugcugugcgc agggcgcgug       60

cccgcccucc uguugugccu ggguuuccac cuccugcagg cggucuugag cacuaccgug      120

aucccauccu gcauuccggg cgaaaguagc gacaacugua cggcccuggu acaaacugag      180

gauaauccca ggguggcaca ggucuccauc accaagugca guagcgacau gaacggguac      240

ugucuccaug gccagugcau uuaucuggug gauauguccc agaauuacug ucggugcgaa      300

guggguuaua ccgggguccg cugugagcac uuuuuccuga cugugcauca accacucagc      360

aaagaauacg uagcccugac cgugaucuug auuauccugu uucucaucac ggucgugggc      420

uccacuuauu acuucuguag gugguaucgg aaccgcaaga guaaagagcc caagaaagag      480

uacgaaaggg ugaccagcgg cgacccagag cugccccagg ucugaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  2073
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt7)

<400>  2073
gggagaaagc uuaccauggc cgagggcgaa aucaccacuu ucaccgcacu gacggagaag       60

uuuaaccugc ccccagggaa uuacaaaaag ccgaaacucu uguauugcag caacgguggc      120

cacuuccuga ggauucuccc cgacgggacu guggauggca cccgggaccg cuccgaucag      180

cauauccaac ugcaguugag ugccgaaagc gucggugagg uguacauuaa guccaccgaa      240

acugggcagu aucuggcgau ggacaccgau ggccuccugu acggcaguca gacgccaaau      300

gaggaguguc uguuucucga aaggcuggag gaaaaccacu auaauacuua caucagcaaa      360

aagcaugccg agaagaacug guucguaggg uugaaaaaga augguuccug caaacggggc      420

ccccgcaccc acuaugggca aaaggcaauu cuguuucucc cacugcccgu gagcuccgac      480

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  2074
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt7)

<400>  2074
gggagaaagc uuaccauggu gggcgucggg gguggcgacg uggaggaugu aacccccagg       60

ccagggggcu gccagaucag cggucgcggg gcccggggcu guaacggcau uccgggggca      120

gccgcguggg aagccgcacu gcccaggcgg cgcccaaggc ggcaccccuc cgugaaucca      180

cgcaguaggg ccgcagguag cccccggacu cgcggcaggc ggaccgagga acgcccaucc      240

gggaguaggc ucggcgaccg gggucgcggg agggcccugc cgggcggccg guuggguggg      300

cgcggcaggg ggcgggcgcc cgagaggguc ggcggucgcg gccgggggag gggcacggcc      360

gcaccacgcg ccgcccccgc agcccggggg agcaggccag gucccgcggg cacuauggcc      420

gcagggucca ucaccacccu gccggcccuc cccgaagaug gcgguagcgg cgcauuccca      480

cccgggcauu uuaaggaccc aaaacgccug uacugcaaga acggcggguu cuuuuugcgg      540

auucaccccg auggcagggu ggacggugug cgggagaaau ccgauccaca uaucaagcug      600

caacuccagg ccgaggaacg cggggucgug aguauuaaag gcguaugugc caauagguau      660

cuggcgauga aggaggacgg ucggcugcuc gcaagcaagu gcgugacuga ugaauguuuc      720

uuuuucgagc gccuggaguc caacaauuac aacaccuaua ggagccggaa auacacgagu      780

ugguaugucg ccuugaagcg cacuggccag uacaaacugg gguccaagac cggcccgggg      840

cagaaagcca uccucuuucu gcccaugagc gcaaaguccu gaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  2075
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt7)

<400>  2075
gggagaaagc uuaccaugca caaguggauc cugaccugga uucuccccac ucuguuguac       60

aggagcugcu uccauaucau uugucuggug ggcaccaucu cccucgccug caacgacaug      120

acgccagagc agauggcaac uaaugucaac uguaguagcc cggaacggca cacccgcucc      180

uaugauuaca uggaaggggg ugacauuagg gugcggcgcc uguuuugcag gacccaaugg      240

uauuugcgga ucgauaaacg cggcaaggua aaagggacuc aggagaugaa gaauaacuac      300

aauaucaugg agauuaggac cguggccguc ggcaucgugg cgauuaaagg uguggaaagu      360

gaguucuauc uggccaugaa caaggagggg aagcucuacg ccaaaaagga auguaaugag      420

gacugcaacu uuaaagaacu gauccuggag aaucauuaua acacguacgc aagcgcaaag      480

uggacucaca auggcggcga gauguucguc gcccucaacc agaaagggau ucccgugcgg      540

gguaagaaaa ccaagaagga acagaaaacu gcgcauuuuc ugccaauggc caucaccuga      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  2076
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt7)

<400>  2076
gggagaaagc uuaccaugaa gcugcucccc agcguggucc ugaaauuguu ccuggccgca       60

gugcucuccg cccugguaac cggcgagagu uuggaaaggc ugcggcgcgg gcucgcggcc      120

gguacuagca acccagaccc gcccaccgug uccacggauc agcugcugcc acucggcggg      180

ggcagggacc ggaagguccg cgaucugcaa gaggcagacu uggaucugcu cagggugacu      240

cugaguagca aaccccaggc ccuggcaacc ccaaauaagg aggaacacgg uaaacggaag      300

aagaaaggga agggcuuggg caaaaagcgc gaccccugcc ucaggaaaua caaggauuuu      360

uguauccaug gggaaugcaa auaugugaag gagcugcggg ccccauccug uauuugccac      420

ccggguuacc auggcgagcg cugucacggg cugagccucc ccgucgaaaa caggcuguau      480

accuacgacc auacuaccau cuuggcggug guagccgugg uccuguccag ugugugccuc      540

cuggugauug ucggccuguu gauguuccgg uaucaccgca ggggugggua cgauguggag      600

aaugaagaga agguaaaacu cggcaugacg aacagccacu gaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  2077
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt7)

<400>  2077
gggagaaagc uuaccaugug ggugaccaag cugcuccccg cccuguugcu gcagcacguc       60

cuccugcauu ugcugcuccu gccaaucgca auuccguacg ccgagggcca aaggaaacgg      120

cgcaacacua uccacgaauu uaagaaaagc gcgaagacca cgcugauuaa aaucgacccc      180

gcccucaaga uuaagacuaa aaaggugaau accgcagauc agugcgccaa cagguguacc      240

cggaauaaag ggcugccauu cacuugcaag gcauucguau uugacaaagc ccgcaagcag      300

uguuuguggu uccccuuuaa cuccaugagu agcgguguga aaaaggaguu cggccaugaa      360

uuugaucugu augagaauaa ggacuacauc aggaacugca ucauugggaa aggccggucc      420

uauaagggua ccgucaguau cacgaaaagc gggauuaagu gucagccaug guccagcaug      480

aucccccacg aacauuccuu ccucccaagu agcuaccgcg gcaaagaucu gcaagagaau      540

uauugcagga acccgcgggg cgaggaaggg ggucccuggu guuuuacuuc caauccagag      600

gugcgcuacg aagugugcga cauuccccag uguagcgagg ucgagugcau gaccugcaac      660

ggcgaaaguu auagggggcu gauggaucac acugaguccg gcaagaucug ucagcggugg      720

gaccaccaga ccccacaucg ccacaaguuc uugcccgaaa gguacccgga uaaagguuuu      780

gacgauaauu acugccggaa ccccgacggg caaccacgcc ccugguguua uacccucgau      840

ccacauacga ggugggagua cugcgcgauu aagacuugug ccgacaauac caugaacgac      900

acugaugugc cccuggaaac caccgagugc auccagggcc agggcgaggg guaucggggu      960

acuguaaaua cgaucuggaa cggcauucca ugucagcgcu gggacagcca auacccgcac     1020

gaacacgaua ugacccccga gaacuucaaa ugcaaggacc ugagggaaaa uuauugucgg     1080

aacccagaug gguccgagag ucccuggugc uucacuaccg acccaaauau cagggugggc     1140

uacugcagcc agauucccaa cugugauaug ucccaugguc aggacugcua ucgcggcaau     1200

gggaaaaacu acaugggcaa ucucagccaa acccggagug ggcugacuug uuccaugugg     1260

gauaagaaca uggaagacuu gcacaggcau aucuuuuggg agccggaugc aagcaagcug     1320

aaugagaacu acugccgcaa uccagacgac gaugcccacg gucccuggug uuauacgggc     1380

aacccccuca uuccauggga cuacugcccc aucagucggu gugaagggga uaccacucca     1440

accaucguca aucuggacca uccggugauu uccugcgcca aaaccaagca gcugagggug     1500

gucaacggca uccccacucg cacgaauauu gguuggaugg ugagcuugcg guauaggaac     1560

aaacacaucu guggcgggag ccucauuaag gaguccuggg uacugaccgc acggcagugc     1620

uucccaaguc gcgaucugaa agacuacgaa gccuggcucg gcauccacga ugugcauggg     1680

aggggcgacg agaaguguaa gcagguccug aacgugagcc aauuggugua uggucccgaa     1740

ggguccgauc ugguccucau gaaacuggcg cggccagccg ugcuggacga uuuuguaagc     1800

acuaucgacu ugcccaauua cggcugcacc auuccggaga agaccaguug cuccguguau     1860

gguuggggcu acacugggcu caucaacuac gauggccugc ugcgcgucgc acaccucuau     1920

auuaugggga augagaaaug uagccagcau cacaggggca aggugacgcu gaacgaaucc     1980

gagaucugcg ccggugcaga gaaaauuggg aguggcccau gugaaggcga cuacgggggu     2040

cccuuggucu gcgagcagca caagaugcgg auggugcugg gcgugaucgu accagggcgc     2100

ggcugugcca uucccaauag gccggguauc uucgugcggg ucgccuauua cgcgaaaugg     2160

auccauaaga uuauccucac cuauaaggug ccccagagcu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  2078
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt7)

<400>  2078
gggagaaagc uuaccauggc caaggcagcc gcgaucggca uugaccuggg gaccacuuac       60

agcugcgugg gugucuucca gcacggcaaa guggagauca uugccaacga ucaagggaau      120

aggaccacgc ccuccuaugu agcauuuacu gacaccgaac ggcucaucgg cgaugccgca      180

aagaaccagg uggcccugaa uccacagaac accgucuucg acgcgaaacg cuugauuggu      240

aggaaguuug gggauccggu ggugcagagu gacaugaaac auuggcccuu ccaagucauc      300

aaugauggcg acaagccaaa ggugcaggua agcuacaaag gcgagacuaa ggccuuuuau      360

cccgaagaga ucuccaguau ggugcugacc aaaaugaagg aaauugcaga ggccuaccuc      420

ggguauccag ucacgaacgc cgugaucacu gugcccgcau acuucaauga uagccagcgg      480

caggccacca aagacgcggg ugucauugcc ggccugaacg uguugcgcau cauuaaugag      540

ccaacugcag ccgcaaucgc cuaugggcug gauaggaccg gcaaggguga acggaacgua      600

cucauuuuug accucggggg cggcaccuuc gaugugucca uccugacgau cgacgacggg      660

auuuuugagg ucaaagccac ugcgggugau acccaccugg gcggggaaga cuucgauaau      720

cgccugguga accauuuugu ggaggaguuc aagaggaagc acaaaaagga caucagccaa      780

aauaaacggg caguccgcag guugcggacu gccugugaac gcgccaagag gacccugucc      840

aguagcaccc aggcaucccu cgagauugau agccuguucg aaggcaucga cuuuuacacu      900

agcauuacgc gggcccgcuu cgaggaacug ugcuccgauu uguuuaggag cacccucgag      960

ccgguggaga aagcgcugcg ggacgccaag cuggauaagg cacagaucca ugaccucgua     1020

cuggugggug gcuccacucg cauccccaaa guccagaagu ugcugcaaga uuucuuuaac     1080

gggagggacc ucaauaaaag uauuaaccca gacgaagccg uggcauacgg cgccgccguc     1140

caggcagcca uccugauggg ggauaagagc gagaacgugc aggaccuguu gcuccuggau     1200

guggcgcccc ugucccucgg ucuggaaacc gccggcgggg uaaugaccgc auugauuaaa     1260

cggaauagca cuaucccaac gaagcaaacc cagauuuuca cuaccuauag ugacaaccag     1320

cccggcgugc ugauccaggu cuacgagggu gaaagggcca ugaccaagga uaauaaccuc     1380

cugggccgcu uugagcuguc cgggaucccg cccgccccac ggggcgugcc ccaaauugag     1440

gucacuuucg acaucgaugc aaaugggauu uugaacguga cggcgaccga caaaagcacu     1500

ggcaaggcca auaaaaucac cauuacuaac gauaagggua ggcucaguaa agaagagauc     1560

gaacgcaugg ugcaggaggc agaaaaguau aaggccgagg acgagguaca gcgggaaagg     1620

guguccgcca aaaaugcacu ggagagcuac gccuuuaaca ugaagagugc ggucgaagau     1680

gaggggcuga aaggcaagau uuccgaggcc gacaaaaaga aagugcucga uaagugucag     1740

gaagucauca guuggcugga cgcaaauacc uuggccgaga aggacgaguu cgaacacaaa     1800

cgcaaggaac uggagcaagu gugcaaccca aucauuagcg gucucuauca gggcgccggg     1860

ggccccgggc caggcgguuu uggggcacag ggcccgaaag gcggguccgg uagcggcccc     1920

acgaucgagg aaguggauug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2079
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt7)

<400>  2079
gggagaaagc uuaccauggc caaggcagcc gcgaucggca uugaccuggg gaccacuuac       60

agcugcgugg gugucuucca gcacggcaaa guggagauca uugccaacga ucaagggaau      120

aggaccacgc ccuccuaugu agcauuuacu gacaccgaac ggcucaucgg cgaugccgca      180

aagaaccagg uggcccugaa uccacagaac accgucuucg acgcgaaacg cuugauuggu      240

aggaaguuug gggauccggu ggugcagagu gacaugaaac auuggcccuu ccaagucauc      300

aaugauggcg acaagccaaa ggugcaggua agcuacaaag gcgagacuaa ggccuuuuau      360

cccgaagaga ucuccaguau ggugcugacc aaaaugaagg aaauugcaga ggccuaccuc      420

ggguauccag ucacgaacgc cgugaucacu gugcccgcau acuucaauga uagccagcgg      480

caggccacca aagacgcggg ugucauugcc ggccugaacg uguugcgcau cauuaaugag      540

ccaacugcag ccgcaaucgc cuaugggcug gauaggaccg gcaaggguga acggaacgua      600

cucauuuuug accucggggg cggcaccuuc gaugugucca uccugacgau cgacgacggg      660

auuuuugagg ucaaagccac ugcgggugau acccaccugg gcggggaaga cuucgauaau      720

cgccugguga accauuuugu ggaggaguuc aagaggaagc acaaaaagga caucagccaa      780

aauaaacggg caguccgcag guugcggacu gccugugaac gcgccaagag gacccugucc      840

aguagcaccc aggcaucccu cgagauugau agccuguucg aaggcaucga cuuuuacacu      900

agcauuacgc gggcccgcuu cgaggaacug ugcuccgauu uguuuaggag cacccucgag      960

ccgguggaga aagcgcugcg ggacgccaag cuggauaagg cacagaucca ugaccucgua     1020

cuggugggug gcuccacucg cauccccaaa guccagaagu ugcugcaaga uuucuuuaac     1080

gggagggacc ucaauaaaag uauuaaccca gacgaagccg uggcauacgg cgccgccguc     1140

caggcagcca uccugauggg ggauaagagc gagaacgugc aggaccuguu gcuccuggau     1200

guggcgcccc ugucccucgg ucuggaaacc gccggcgggg uaaugaccgc auugauuaaa     1260

cggaauagca cuaucccaac gaagcaaacc cagauuuuca cuaccuauag ugacaaccag     1320

cccggcgugc ugauccaggu cuacgagggu gaaagggcca ugaccaagga uaauaaccuc     1380

cugggccgcu uugagcuguc cgggaucccg cccgccccac ggggcgugcc ccaaauugag     1440

gucacuuucg acaucgaugc aaaugggauu uugaacguga cggcgaccga caaaagcacu     1500

ggcaaggcca auaaaaucac cauuacuaac gauaagggua ggcucaguaa agaagagauc     1560

gaacgcaugg ugcaggaggc agaaaaguau aaggccgagg acgagguaca gcgggaaagg     1620

guguccgcca aaaaugcacu ggagagcuac gccuuuaaca ugaagagugc ggucgaagau     1680

gaggggcuga aaggcaagau uuccgaggcc gacaaaaaga aagugcucga uaagugucag     1740

gaagucauca guuggcugga cgcaaauacc uuggccgaga aggacgaguu cgaacacaaa     1800

cgcaaggaac uggagcaagu gugcaaccca aucauuagcg gucucuauca gggcgccggg     1860

ggccccgggc caggcgguuu uggggcacag ggcccgaaag gcggguccgg uagcggcccc     1920

acgaucgagg aaguggauug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2080
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt7)

<400>  2080
gggagaaagc uuaccauggc caccgcaaag ggcaucgcca uugggaucga ccuggguacu       60

accuacagcu gcgugggcgu cuuccagcac gggaaagugg agauuaucgc gaacgaucaa      120

ggcaauagga cgacucccuc cuauguagcc uuuaccgaca ccgaacggcu cauuggugau      180

gcagccaaga accagguggc aaugaaucca cagaacacug ucuucgacgc caaacgccug      240

aucgggagga aguuuaauga uccgguggug caggcggaca ugaaauugug gcccuuccaa      300

gucaucaacg agggcggcaa gccaaaggug cugguaaguu acaaagggga aaauaaggcc      360

uuuuaucccg aggaaauuag cuccauggug cucaccaaac ugaaggagac ggcagaggcc      420

uucuuggguc auccagucac uaacgccgug aucaccgugc ccgcauacuu uaaugauagu      480

cagcggcagg ccacuaaaga cgcgggcguc auugccgggc ugaacgugcu ccgcaucauu      540

aaugaaccaa ccgcagccgc aaucgccuau ggccuggaua agggugggca gggcgagagg      600

cacguacuga uuuucgaccu cggcgggggu accuuugaug ugagcauccu gacgaucgac      660

gauggcauuu ucgaagucaa agccacugcg ggggacaccc auuugggcgg ugaggacuuu      720

gauaaccggc ugguguccca cuucguggag gaguucaagc gcaagcauaa aaaggacauc      780

agccaaaaua aaagggcagu ccggcgccuc aggacugccu gugagcgggc caagcgcacc      840

cuguccagua gcacccaggc aaaccuggaa auugauuccu uguacgaggg caucgacuuu      900

uauacuagca uuacgagggc ccgguucgaa gaacucugcg cggaucuguu ucgcgggacc      960

cuggagccgg uggaaaaagc ccucagggac gcaaagaugg auaaggccaa aauccacgac     1020

aucguacugg ugggcgggag uacucggauu cccaaggucc agcgcuugcu gcaggauuac     1080

uucaauggua gggaccucaa caaauccauc aacccagaug aggcaguggc cuacggcgcc     1140

gcaguccaag ccgcgauucu gaugggggac aagagcgaaa aagugcagga ccuguugcuc     1200

cuggaugugg caccccuguc ccucggccug gagaccgccg guggcguaau gaccgccuug     1260

aucaagcgga auaguacuau uccaacgaag cagacccaaa ucuuuacuac cuauagcgac     1320

aaccagcccg gggugcugau ccaggucuac gaaggcgaga gggccaugac caaagauaau     1380

aaccuccugg ggcgcuucga ccugacuggc auuccgcccg caccacgggg ugugccccag     1440

aucgagguca cguuugauau ugacgcgaau gggaucuuga acgugaccgc cacugauaag     1500

uccaccggca aagugaauaa gauuacuauc accaacgaca aagguaggcu cagcaaggaa     1560

gagauugaac gcaugguacu ggaugcagag aaguauaaag ccgaagacga ggugcaacgg     1620

gagaagaucg ccgccaaaaa ugcacuggaa aguuacgcgu ucaacaugaa guccgucgug     1680

agcgaugagg gccucaaagg gaagaucagu gaauccgaca aaaauaagau ucuggauaag     1740

uguaacgagu ugcugagcug gcucgagguc aaucagcugg ccgaaaaaga cgaguuugac     1800

cacaagagga aagaacugga gcagaugugc aacccaauca uuacgaaguu guaucagggc     1860

ggguguaccg gccccgcaug cgguacuggg uacgugccag gccgcccggc caccggcccc     1920

acuaucgaag agguggauug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2081
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt7)

<400>  2081
gggagaaagc uuaccaugag cgccaggggc cccgcaaucg ggauugaccu ggguaccacu       60

uacuccugcg ugggcgucuu ccagcacggg aagguggaga ucauugccaa cgaucagggc      120

aaucggacca cgccaaguua uguagcguuu acugacaccg aacgccucau cggugaugcc      180

gccaaaaacc agguggcaau gaauccgacc aacacuauuu ucgacgcaaa gaggcugauc      240

gggcggaaau uugaggaugc caccguccag agcgacauga agcauuggcc cuuccgcgug      300

guguccgaag gcggcaaacc aaagguccag guggaguaca agggggaaac gaaaaccuuu      360

uuccccgagg agaucaguag caugguauug acuaagauga aagaaauugc ggaggccuau      420

cuggguggca aggugcacuc cgcagucauc acugugccag ccuacuuuaa ugauagccaa      480

aggcaggcca ccaaagacgc agggaccauu acgggccuca acgugcugcg gaucauuaau      540

gaacccacug ccgcggccau cgcauauggu uuggauaaga aagggugugc cggcggcgag      600

aagaacgucc ugauuuucga ccucgggggu ggcaccuuug auguguccau ccugacuauc      660

gaggacggga uuuucgaagu aaagaguacc gcaggcgaua cccaucuggg uggcgaggac      720

uuugacaauc gcauggugag ccaccucgcc gaagaguuca aaaggaagca uaaaaaggau      780

aucgggccaa acaaacgggc cguccgcagg cugcggacug cgugcgaacg cgcaaagagg      840

acguugucca gcaguaccca ggccuccauu gagaucgaca gccuguacga gggcguggau      900

uucuauacuu ccauuacccg ggcccgcuuu gaggaacuca augcagaccu guucaggggg      960

acccuggaac cgguggagaa ggccuugcgg gaugcgaaac ucgacaaggg ucagauccaa     1020

gaaaucgucc uggugggcgg gaguacucgc auucccaaaa uccagaagcu gcuccaggac     1080

uuuuucaacg gcaaagagcu gaauaagagc auuaacccag augaggccgu agcauacggu     1140

gccgcagugc aggccgccau cuugauuggc gauaaguccg aaaaugucca agaccugcuc     1200

cugcuggaug ugacgcccuu gagccucggg aucgagaccg caggcggggu caugacucca     1260

cugaucaaaa ggaacaccac cauucccacu aagcagacgc agaccuuuac uaccuacagu     1320

gacaaccaau ccagcgugcu ggugcaggua uaugaaggcg agcgggccau gacuaaagac     1380

aauaaccucc uggguaaguu cgauuugacc gggaucccgc ccgcgccaag gggcgugccc     1440

cagauugaag ucacguuuga caucgaugcc aaugguauuc ugaacgugac cgcagccgac     1500

aaaaguacug gcaaggagaa uaagaucacc auuacuaacg auaaagggcg ccucuccaag     1560

gacgauaucg accggauggu ccaggaggcc gaaagguaca aaagcgagga ugaagcaaau     1620

cgcgaccggg uggcggccaa gaacgcacug gagagcuaua ccuacaauau caaacaaacg     1680

guggaggaug aaaagcugag gggcaaaauu uccgagcagg acaagaacaa gaucuuggau     1740

aaaugucagg aaguaauuaa uuggcucgac cgcaaccaga uggccgagaa ggacgaauau     1800

gagcacaaac aaaaggagcu ggaacgggug ugcaauccaa ucauuaguaa acuguaccaa     1860

gggggccccg gugggggcag cggcgggggu ggcuccgggg ccagcggcgg uccaaccauc     1920

gaggaagucg auugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  2082
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt7)

<400>  2082
gggagaaagc uuaccaugag cguggucggc aucgaccugg gguuccaguc cugcuacgug       60

gccguagcaa gggccggugg cauugagacc aucgcgaacg aauauaguga ucgguguacu      120

cccgccugca uuagcuuugg gccaaagaau cgcuccaucg gcgcagccgc aaaaagucaa      180

gugauuagca acgccaagaa uaccguccag gguuucaaaa gguuucacgg gcgggcguuc      240

uccgacccgu uuguggaggc cgaaaagagc aaccucgcau acgauaucgu gcagcugccc      300

acgggcuuga cuggcaucaa agucaccuau auggaggaag aacgcaauuu caccacugaa      360

caggugaccg ccaugcugcu cuccaagcug aaggaaacgg ccgagagugu auugaaaaag      420

ccaguggucg acuguguggu gagcgucccc ugcuuuuaca cugaugcaga aaggcggucc      480

gugauggacg ccacccaaau ugcggggcug aacugucucc gccugaugaa ugagacuacc      540

gccguagcac uggccuaugg uaucuacaaa caggaucucc cagcacugga ggaaaagccc      600

aggaacgugg ucuucgugga caugggccau agcgccuauc aggugagugu cugcgccuuu      660

aaucggggga aauugaaggu gcuggcgacc gcauucgaua cgacucucgg cggucgcaaa      720

uuugacgagg uacuggugaa ccacuucugu gaagaguucg ggaagaagua caaacuggau      780

auuaagucca aaaucagggc cuugcuccgg cugagccagg aaugcgagaa gcugaaaaag      840

cucauguccg ccaaugcaag ugaccugcca uugagcauug aguguuuuau gaacgauguc      900

gacguguccg gcaccaugaa ucgcggcaag uuccuggaaa ugugcaacga ccuccuggcc      960

agggucgagc cgccccugcg gagcguguug gaacaaacua aacucaagaa agaggauauc     1020

uacgcggugg aaauuguagg gggugccacc cgcaucccag cagugaagga gaaaaucagu     1080

aaguuuuucg gcaaggagcu guccaccacu cugaaugccg acgaagcagu cacgaggggg     1140

ugcgcccucc agugugccau ucugagcccc gcauuuaaag ugcgggaguu caguaucacc     1200

gaugucgugc cauaucccau uuccuugcgc uggaacagcc cggccgaaga gggcagcucc     1260

gacugcgaag uguuuaguaa gaaccaugcg gcccccuuca gcaaaguacu gacuuuuuac     1320

aggaaggagc cauucacccu cgaggcauau uacuccagcc cccaggaucu gccauauccc     1380

gacccagcca ucgcccaguu uagugugcaa aaagucaccc cgcaguccga ugguagcucc     1440

aguaagguga aggucaaagu gcgggugaau guacacggca uuuucagcgu cuccagcgca     1500

agucuggugg aagugcauaa guccgaggaa aacgaggagc ccauggaaac ugaccagaau     1560

gcgaaagagg aagagaagau gcaagucgau caggaggagc cacacgugga ggaacagcag     1620

caacagacgc ccgccgagaa caaagcagaa agcgaggaaa uggagaccuc ccaggccggg     1680

aguaaggaca aaaagaugga ucagccaccc caagccaaga aagcaaaggu gaaaacuagc     1740

accguagacu ugccgaucga gaaucagcuc cuguggcaga ucgacaggga aaugcugaac     1800

cucuacauug agaaugaagg caagaugauc augcaggaua aacuggagaa ggaacgcaac     1860

gacgccaaga augcggucga ggaguaugug uacgaaaugc gggauaaauu guccggggag     1920

uacgaaaagu uugugagcga ggacgauagg aacaguuuca cccugaaacu cgaggacacu     1980

gaaaauuggc uguaugagga uggugaagac caaccaaagc aggucuacgu ggauaaacug     2040

gccgaguuga agaaccuggg ccagcccauu aagauccgcu uccaggaauc cgaggagcgg     2100

cccaaacucu uugaggagcu ggggaagcaa auucagcagu auaugaaaau caucagcucc     2160

uucaagaaua aagaagacca auacgaucac cucgacgcag ccgauaugac gaagguagag     2220

aaaagcacca acgaagccau ggaguggaug aauaacaagc ugaacuugca gaauaagcag     2280

agucugacua uggacccagu ggucaaaagc aaggagauug aagcaaaaau caaggagcuc     2340

accuccacuu guagucccau uaucagcaaa ccaaagccga agguggaacc cccaaaagag     2400

gagcagaaga acgccgaaca aaauggcccc guggacgguc agggcgauaa cccagggccc     2460

caggcggccg agcagggcac cgacacggca gucccguccg auagcgacaa aaagcugcca     2520

gaaauggaua uugacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  2083
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt7)

<400>  2083
gggagaaagc uuaccaugag cguggucggc aucgaccugg gguuccucaa cugcuacauu       60

gccguggcaa gguccggugg caucgagacc auugccaaug aauauaguga ucgguguacu      120

cccgcgugca ucagccuggg gucccgcacc agggccauug gcaacgcagc caagagucag      180

aucguaacga augugcggaa cacuauccac gguuuuaaaa aguugcaugg gcgcagcuuc      240

gacgauccaa uuguccaaac cgagaggauc cggcugccgu acgaacucca gaaaaugccc      300

aauggcuccg caggcgugaa ggugcgcuau cuggaggaag agaggccauu ugccauugag      360

caggucaccg ggauguugcu ggcgaaacuc aaggaaacua gcgagaacgc ccugaagaaa      420

cccguggcag acuguguaau cuccauucca aguuucuuua ccgaugccga acggcgcagc      480

gugauggccg cagcccaggu cgcgggucug aauugccuca ggcugaugaa cgagacgacu      540

gccguggcau uggccuacgg caucuauaag caagaccugc ccccacucga ugagaaaccg      600

cggaaugugg ucuucauuga cauggggcac uccgcauacc aggugcuggu augugccuuu      660

aacaagggca aacugaaggu guuggccacc acuuucgauc ccuaucucgg ugggcgcaau      720

uuugacgaag cgcuggucga uuacuucugc gacgaguuua aaaccaagua caagaucaac      780

gugaaagaaa auagcagggc acugcuccgg cuguaucagg agugugaaaa guugaaaaag      840

cugaugagug ccaacgccuc cgaucuccca cugaauaucg agugcuucau gaacgaccug      900

gacgugagcu ccaaaaugaa ccgcgcacag uucgagcaau ugugugccag ucuccuggcg      960

agggucgaac ccccacugaa ggccgugaug gagcaggcaa aucuccagcg ggaagauauu     1020

agcuccaucg agauuguagg cggcgccacc cgcauccccg cagugaagga acagauuacg     1080

aaauuuuucc ugaaggacau cagcacuacc uugaacgccg augaggccgu cgcaaggggg     1140

ugcgcccugc aaugcgcgau ccucaguccg gccuuuaaag ugcgggaguu cuccauuacu     1200

gaccuggucc ccuacagcau cacccugagg uggaagacca guuuugaaga ugguuccggc     1260

gagugugaag uguucugcaa aaaucaucca gcacccuuua gcaaggugau uacuuuccac     1320

aagaaagagc cauuugaauu ggaggccuuc uauacgaacc uccaugaggu acccuaccca     1380

gacgcccgca ucgggagcuu uaccauucag aauguguucc cgcaguccga uggcgacagu     1440

agcaagguca aagugaaggu ccgggugaac auccacggua ucuuuuccgu ggcaagcgcg     1500

aguguaauug aaaaacaaaa ucuggagggc gaucacuccg acgcccccau ggaaacugag     1560

accagcuuca agaacgagaa uaaggauaac auggacaaaa ugcaagugga ccaggaagag     1620

gggcaucaga agugucacgc agaacauacc ccagaggaag agaucgauca cacuggcgcc     1680

aaaacgaagu ccgccgucag ugacaaacag gauaggcuga aucagacccu caagaaaggg     1740

aaggugaagu ccauugaccu gcccauccag uccagcuugu gccgccagcu gggucaagau     1800

cuccugaaca guuauauuga gaaugaaggc aaaaugauca ugcaggacaa gcuggagaaa     1860

gaacggaacg augcaaagaa ugccgucgag gaauacgugu augacuucag ggaucgcuug     1920

gggacugugu acgagaaauu uauuacccca gaggaccugu ccaagcucag cgcgguacug     1980

gaagauaccg agaacuggcu cuacgaagac ggcgaggauc agcccaagca ggucuaugug     2040

gacaaacugc aagaauugaa gaaauacggu cagccgaucc agaugaagua uauggagcac     2100

gaggaacggc caaaagcccu gaacgaccuc ggcaagaaga uccagcuggu gaugaaaguc     2160

auugaggcau acaggaauaa ggaugaacgg uaugaccauc uggaucccac ugagauggag     2220

aaaguggaaa aguguaucuc cgacgccaug aguugguuga acagcaaaau gaaugcccaa     2280

aacaagcugu cccucacgca ggaucccgug guaaaaguca gcgagauugu ggcaaagagu     2340

aaggaacugg acaauuucug caacccaauc auuuacaaac ccaagccaaa agccgaggug     2400

ccggaagaua agcccaaagc gaauagcgag cacaacgggc caauggacgg ccagagcggg     2460

accgagacua aguccgauag caccaaggac aguagccaac auacuaaauc caguggcgaa     2520

auggaggucg auugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  2084
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt7)

<400>  2084
gggagaaagc uuaccaugaa gcugagccuc guggccgcaa ugcuguugcu gcucuccgcc       60

gcgagggccg aggaagagga caaaaaggaa gaugucggca ccgugguagg gaucgaccug      120

gguacuaccu acaguugcgu gggcgucuuc aaaaacgggc ggguggagau uaucgcaaau      180

gaucagggca accgcauuac gcccagcuau guggccuuua cuccagaagg ugagagguug      240

aucggggacg cagccaagaa ucaacugacc uccaacccgg agaauaccgu cuucgaugcg      300

aaacggcuca uuggccgcac uuggaacgac cccagugugc agcaggauau caaguuucug      360

ccauucaagg uaguggagaa aaagaccaaa cccuacaucc aggucgacau uggcgggggu      420

caaacgaaga cuuuugcccc agaagaaauc agcgcaaugg ugcugaccaa aaugaaggag      480

acugccgagg ccuaucucgg caaaaaggug acccacgcag ucgugaccgu acccgccuac      540

uucaaugaug cgcagaggca ggccacgaag gacgcaggga cuauugccgg ccugaacgug      600

augcggauca uuaaugaacc aaccgcagcc gccaucgcgu augguuugga uaaacgcgag      660

ggggaaaaga acauucuggu cuuugaccuc ggcggcggga cuuucgaugu gucccugcug      720

accaucgaca augguguguu ugaggucgug gcaaccaacg gcgacacuca ucucgggggc      780

gaagauuucg accagagggu aauggagcac uuuaucaaau uguacaagaa aaagacgggu      840

aaggaugugc ggaaagacaa ucgcgccguc caaaagcuga ggcgggaggu ggaaaaagcc      900

aagcgcgcac ugagcuccca gcaucaggcc aggauugaga ucgaaaguuu cuaugagggc      960

gaagauuuca gcgagacccu cacucgggcg aaauuugagg aacugaacau ggacuuguuc     1020

cgcuccacca ugaagccggu ccagaaggug cuggaggaua gcgaccucaa aaagagugau     1080

auugacgaaa ucgugcuggu agggggcucc accaggauuc ccaaaaucca acagcuggug     1140

aaggaguuuu ucaaugggaa agaaccaagc cgggguauca accccgauga ggccgucgca     1200

uacggcgccg cagugcaggc cggggucuug uccggcgacc aagacacugg ugaucucgug     1260

cugcuggacg uguguccacu cacgcugggc auugagaccg uagggggcgu gaugacuaag     1320

uugauccccc gcaacaccgu cgugccgacc aagaaaaguc agauuuuuag cacugccucc     1380

gauaaucagc ccacggucac caucaaggug uacgaagggg agaggccacu gacuaaagac     1440

aaccaccucc ugggcaccuu cgaucugacu gguauucccc cagcaccccg gggcgugcca     1500

cagaucgaag uaaccuuuga gaucgacguc aaugggauuu ugagggugac ggccgaggau     1560

aaggguaccg gcaacaaaaa uaagaucacu auuaccaacg accaaaaucg ccucacuccg     1620

gaagagaucg aacggauggu gaacgaugcg gagaaauucg ccgaagagga caagaagcug     1680

aaagagagga uugauacccg caaugaacug gagagcuaug cauacagucu caagaaccag     1740

aucggggaca aagaaaagcu gggcgggaaa uuguccagcg aggauaagga aacgauggag     1800

aaggccgucg aggagaaaau ugaauggcug gaaagucauc aggacgccga caucgaggau     1860

uuuaaggcga aaaagaaaga acucgaggag aucgugcagc ccauuaucuc caagcuguau     1920

ggcagcgcag guccaccccc aaccggggaa gaggacacug ccgaaaagga ugagcuguga     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  2085
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt7)

<400>  2085
gggagaaagc uuaccaugca ggcccccagg gagcuggcag ugggcaucga ccucgggacc       60

acuuacagcu gcgucggugu guuccaacag ggccggguag aaauucuggc caacgaucag      120

gggaaucgca ccacgccauc cuauguggcg uuuacugaca ccgagagguu ggucggcgau      180

gccgcaaaga gucaggccgc acugaacccg cacaauaccg uguucgacgc caaacggcuc      240

aucggucgca aguuugcgga uacuaccgug caaagcgaca ugaaacauug gcccuucagg      300

gucguguccg aagggggcaa gccaaaagua cggguguguu accgcggcga ggauaagacg      360

uuuuaucccg aagagauuag uagcaugguc cuguccaaga ugaaagagac ugccgaagca      420

uacuuggggc agccagugaa gcacgccgug aucaccgucc ccgccuauuu caacgacagc      480

cagaggcagg caacuaaaga ugccggugcg auugccggcc ugaaugugcu ccggaucauc      540

aacgagccaa ccgcagccgc aauugccuac gggcuggacc gcaggggcgc cggugaacgg      600

aauguacuga ucuuugaucu cgggggcggc accuucgacg uguccguccu gaguauugau      660

gcgggggugu uugaggugaa ggcaacggcc ggugacacuc auuugggcgg ggaggacuuc      720

gauaaccgcc uggucaauca cuuuauggaa gaguucaggc ggaaacaugg caaggaccuc      780

agcgguaaca aacgcgcccu gaggcggcug cgcaccgcau gcgaaagggc caagcggacu      840

uuguccagca guacccaagc gacccucgag aucgauuccc uguucgaagg cguggacuuu      900

uauacuagca uuacgagggc ccgcuucgag gagcuguguu ccgaucucuu ucggaguacc      960

cuggaaccgg uagagaaggc auugagggac gccaaacugg auaaggcaca gauccacgac     1020

gugguccucg ucgggggcag cacucgcauu cccaaagugc agaagcugcu gcaggauuuc     1080

uuuaauggga aagaauugaa caaguccauc aauccagacg aggccguggc cuacggugca     1140

gccgugcaag cggccguacu caugggcgau aagugcgaaa aagugcagga ccugcugcuc     1200

cuggacgucg cacccuugag ccuggggcuc gagaccgccg gcggugugau gaccacucug     1260

auccagcgga acgccacgau uccaaccaag caaacucaga ccuucaccac uuacagugau     1320

aaucagcccg gcgucuuuau ccagguguau gagggggaaa gggcaaugac gaaagacaac     1380

aaccuguugg gccgcuucga gcucuccggg auuccgcccg cgccacgggg cgugccccaa     1440

aucgaaguaa ccuuugauau ugacgccaau gguauccuga gcgugacugc aaccgauagg     1500

aguacuggga aggccaacaa aaucaccauu acgaaugaca agggccggcu guccaaggag     1560

gaagucgagc gcauggugca cgaggccgaa caguacaaag cagaggauga agcccagagg     1620

gaccgggucg cggccaagaa cagccucgag gcacaugugu uccacgugaa agguagccug     1680

caggaggaau ccuugcgcga uaagauccca gaggaagaca ggcggaaaau gcaagauaag     1740

ugucgcgagg uacuggccug gcucgaacau aaucagcugg ccgagaagga ggaauaugag     1800

caccagaaaa gggaacugga gcagauuugc cggcccaucu uuaguagguu guacggcggg     1860

ccaggcgucc ccgggggcag cuccuguggu acccaagcac gccaggggga cccgagcacu     1920

ggcccaauua ucgaagaggu ggauugagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  2086
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt7)

<400>  2086
gggagaaagc uuaccaugca ggcccccagg gagcuggcag ugggcaucga ccucgggacc       60

acuuacagcu gcgucggugu guuccaacag ggccggguag aaauucuggc caacgaucag      120

gggaaucgca ccacgccauc cuauguggcg uuuacugaca ccgagagguu ggucggcgau      180

gccgcaaaga gucaggccgc acugaacccg cacaauaccg uguucgacgc caaacggcuc      240

aucggucgca aguuugcgga uacuaccgug caaagcgaca ugaaacauug gcccuuccag      300

gucguguccg aagggggcaa gccaaaagua aggguguguu accggggcga ggauaagacg      360

uuuuaucccg aagagauuag uagcaugguc cuguccaaga ugaaagagac ugccgaagca      420

uacuuggggc agccagugaa gcacgccgug aucaccgucc ccacuuauuu cagcaacucc      480

cagcgccaag ccaccaaaga cgcaggggcc auugcgggcc ugaaggugcu cccaaucauc      540

aaugaggcca ccgcagccgc aauugccuac gggcuggaua ggcggggcgc cgguaaacgc      600

aacguacuga ucuuugaccu cgggggcggc acguucgaug ugaguguccu gagcauugac      660

gcgggggugu uugaagugaa ggcaacugcc ggugauaccc auuugggcgg ggaggacuuc      720

gacaauaggc uggucaacca cuuuauggag gaguuccggc gcaaacaugg caaggaucuc      780

uccgguaaua agagggcccu gcggcgccug aggacugcau gcgagcgggc caaacgcacc      840

ccgagcaguu ccacccaggc gacuuuggaa aucgacagcc ucuucgaggg cguggauuuu      900

uauaagucca uuacgagggc ccgguucgaa gaacugugua gugaccuguu uaggagcacc      960

cucgagcccg uagaaaaagc acugcgcgau gccaaguugg acaaagcaca gauccacgau     1020

uucgugcugg guggcgggcu ccacucccau ccacagggug ccgaggucgc cgcaggccug     1080

cugcaacggc agggggccga acaggagcac caacccugag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  2087
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt7)

<400>  2087
gggagaaagc uuaccaugag caagggcccc gccgugggga ucgaccuggg uaccacuuac       60

uccugcgucg gcguguucca gcacgggaaa guagagauua ucgcaaacga ucaaggcaau      120

aggaccacgc caaguuaugu ggccuuuacu gacaccgaac ggcucauugg ugaugcggcc      180

aagaaccagg ucgcaaugaa uccgaccaac acuguguucg acgccaaacg ccugaucggg      240

aggcgguuug augacgcagu gguccagagc gauaugaagc auuggcccuu caugguggua      300

aaugacgccg gccgcccaaa agugcagguc gaguacaagg gcgaaaccaa guccuuuuau      360

cccgaggaag ugaguagcau gguguugacg aaaaugaagg agauugcgga ggccuaccug      420

gggaaaacug ucaccaacgc agugguaacu gugccagccu auuucaauga uucccaaagg      480

caggccacca aggacgcagg uaccaucgcc ggccucaacg uccugcggau cauuaaugaa      540

cccacggcgg ccgcaaucgc cuacggguug gauaaaaagg ugggcgcaga gcgcaacgug      600

cugauuuuug accucggugg gggcacuuuc gaugucagca uccugaccau ugaagacggc      660

aucuuugagg ugaaauccac ugccggggac acccaccugg guggcgagga uuucgacaau      720

aggaugguaa accauuuuau ugccgaauuu aagcggaagc acaaaaagga uaucagugag      780

aauaaacgcg cggugaggcg gcuccgcacc gcaugugaaa gggccaagcg gacucugagc      840

uccagcacgc aggccaguau cgagauugac uccuuguaug aagggaucga uuucuacacc      900

agcauuacuc gcgcaagguu ugaggagcug aacgccgacc ucuuccgggg cacccuggau      960

ccagucgaaa aagcgcugcg cgacgccaag uuggauaagu cccagaucca ugacauugug     1020

cucgucggug gcaguaccag gaucccgaaa auccaaaagc ugcugcagga uuucuucaau     1080

gggaaagagc ucaacaagag cauuaacccc gacgaagcag uggccuacgg cgcagccgug     1140

caggccgcaa uccuguccgg ggacaaaagc gagaauguac aggauuugcu gcuccuggac     1200

gugacuccac ugaguuuggg uauugaaacg gccggcgggg ucaugaccgu gcucaucaag     1260

cggaacacua ccauucccac caagcaaacu cagacguuua ccacuuauuc cgauaaucag     1320

ccaggcgucc ugauccaagu guacgagggu gagagggcga ugaccaaaga caacaaucug     1380

cucggcaagu ucgaacugac ugggauuccc ccggcacccc gcggcgugcc acagaucgag     1440

guaaccuuug auaucgacgc caacgggauu uugaauguga gcgccgucga uaaaaguacg     1500

ggcaaggaaa acaaaaucac cauuacuaau gacaaggguc ggcuguccaa ggaggauauc     1560

gaaaggaugg ugcaggaggc cgagaaauau aaggcagaag acgagaaaca gcgcgauaag     1620

gucagcagca aaaacucccu cgaaaguuac gcguucaaua ugaaggccac cguggaggac     1680

gagaaacugc aagggaagau uaacgaugaa gacaagcaga aaauccugga caagugcaau     1740

gagaucauua acugguugga uaaaaaucag acugcagaaa aggaggaauu ugagcaccag     1800

caaaaagagc ucgaaaaggu guguaacccc aucauuacca agcuguauca gagcgccggc     1860

gguaugccag gcgggaugcc cggcggguuc ccaggcggug gggccccgcc cuccggcggc     1920

gcaagcagug ggccaacgau cgaggaagua gacugaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  2088
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt7)

<400>  2088
gggagaaagc uuaccaugau cagcgccucc agggcagccg cggcccggcu ggugggcgca       60

gccgcaaguc gcgggcccac cgccgcgagg caccaggaca gcuggaacgg ucucucccau      120

gaggccuucc ggcuggucag ucgcagggau uacgcaagcg aagccauuaa gggcgccgug      180

guagggaucg acuugggcac uaccaauucc ugcguggcag ucauggaggg uaaacaagcc      240

aaggugcugg aaaacgcgga gggggcccgg acgacuccaa gcguggucgc auuuaccgcc      300

gauggcgaac gccucguggg caugccggca aaaaggcagg ccguaaccaa ucccaacaau      360

acuuucuaug ccaccaagcg gcugauuggg cgcagguacg acgauccaga ggugcagaaa      420

gacaucaaga acguccccuu uaagauugug cgggcgucca auggugaugc auggguggag      480

gcccacggca aauuguauag uccaagccag aucggggccu ucguccugau gaagaugaaa      540

gaaacggcag agaacuaccu cggccauacu gccaagaaug cggugaucac cguacccgcc      600

uauuuuaacg acucccaacg ccaggcaacu aaagaugccg gucagauuag cgggcugaau      660

gugcugaggg ucaucaacga accaaccgca gccgcccucg cauacggccu ggacaagagu      720

gaggauaaag ugauugccgu guaugacuug ggcgggggua ccuucgauau cuccauucug      780

gagauccaga agggcgucuu ugaaguaaag agcacgaaug gggacacuuu ccucggcggu      840

gaggacuuug aucaagcgcu gcugcggcac auugugaaag aguucaagcg cgaaaccggc      900

guggacuuga cuaaagauaa cauggcccuc cagagggucc gggaagcagc cgagaaggcc      960

aaaugugagc uguccaguag cgugcagacc gacaucaauc ugccguaccu caccauggau     1020

uccagcgggc ccaagcaucu gaacaugaag uugacucgcg cacaguuuga aggcaucguc     1080

acggaccuga uuaggcggac caucgcgcca ugccaaaaag ccaugcagga ugcagaggug     1140

aguaaguccg acauugggga agugauccuc guagguggca ugacuaggau gcccaaagug     1200

cagcaaaccg uccaggaucu guucgggcgc gccccaagca aggccgugaa ccccgacgag     1260

gcagucgcca uuggcgcggc cauccagggu ggcgugcugg caggggaugu gaccgacgua     1320

uugcuccugg acgugacucc gcugagucuc ggcaucgaaa cgcugggcgg ggucuucacc     1380

aaauugauua aucggaacac uaccaucccc accaagaagu cccagguguu uagcacugcc     1440

gccgaugguc aaacgcaggu cgagauuaaa gugugucagg gggagaggga aauggcaggc     1500

gacaauaagc ugcucgguca guucacccug aucggcauuc cacccgcccc acgcggggug     1560

ccccaaaucg agguaacuuu ugauaucgac gcgaacggca uuguccacgu gagcgccaaa     1620

gauaagggga ccggccggga acagcagauc gugauucagu ccaguggugg gcugagcaaa     1680

gacgauaucg agaauauggu caagaacgca gaaaaguacg ccgaggagga caggcgcaaa     1740

aaggaacggg uggaggcagu gaauauggcc gaaggcauua uccacgauac ugagaccaaa     1800

auggaggagu ucaaggacca auugccagcg gaugaaugca acaaacucaa ggaagagauu     1860

uccaaaauga gggaacugcu ggcccggaag gacagcgaga cgggcgagaa uauccgccag     1920

gcagccaguu cccuccagca ggccagccug aaguuguuug aaauggcaua uaaaaagaug     1980

gccuccgaga gggaagggag ugguagcucc ggcaccgggg agcaaaaaga agaucagaag     2040

gaggagaaac agugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  2089
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt7)

<400>  2089
gggagaaagc uuaccauggc cgacaaggag gcaggcggga gcgauggucc cagggaaacc       60

gccccaacuu ccgcguacag uagcccggcc cggucccugg gcgacaccgg gaucacgccc      120

cucaguccaa gccacauugu gaacgauacu gacuccaaug ucagcgagca gcaauccuuc      180

cuggugguag uggcagucga uuuuggcacc accaguagcg guuaugccua cuccuucacu      240

aaagaacccg agugcaucca ugugaugagg cgcugggaag ggggcgaccc aggcgugagc      300

aaccagaaga cccccacgac uauuuugcug accccagagc ggaaauuuca caguuucggg      360

uaugcagccc gcgauuuuua ccaugaccuc gauccgaaug aggcgaagca guggcuguau      420

uuggaaaaau ucaagaugaa gcugcacacu accggugacc ucaccaugga uacggaccug      480

acugccgcaa acggcaaaaa ggucaaagcc cuggagaucu uugccuacgc acuccaguau      540

uucaaggaac aagcccugaa agaguugucc gaucaggcgg ggagcgaguu ugaaaauucc      600

gacgugaggu ggguaauuac cgugcccgcc aucuggaagc agccagcaaa acaguucaug      660

cggcaagccg cauaccaggc cggccuggcc agucccgaga acagcgaaca gcucaucauu      720

gcgcuggagc cagaagcagc cuccaucuac ugucgcaagc ugagguugca ucagaugauu      780

gagcucagca guaaggccgc agucaauggu uauuccggga gcgacacugu gggcgccggc      840

uuuacccaag cgaaagagca cauccggcgc aacaggcaga gucggaccuu ccugguggaa      900

aaugucauug gggagaucug guccgaacug gaggaaggug auaaguacgu gguaguggac      960

agcggcgggg gcacugucga ucucacggug caccagauuc gccugcccga gggucauuug     1020

aaagagcugu auaaggccac cggcgggccg uacggcagcc ucggggugga cuaugaguuc     1080

gaaaaacugc uguacaagau cuuuggugaa gauuucaucg agcaauuuaa gauuaaaagg     1140

cccgcagccu gggucgacuu gaugaucgca uucgaauccc ggaagcgcgc cgccgcacca     1200

gauaggacua acccccucaa uauuacccug ccauuuaguu ucaucgacua uuacaaaaag     1260

uuucggggcc acagcgugga gcaugcccug cgcaaaucca acguagauuu cgugaagugg     1320

agcagucagg ggaugcucag gauguccccc gacgcgauga augcccuguu uaagccaacc     1380

auugauagca ucaucgagca cuugcgggac cuguuccaga aaccggaagu cuccacugug     1440

aaguuucucu uccuggucgg cgguuuugca gaggcacccc uguugcagca agccgugcag     1500

gccgcguucg gcgaccagug caggauuauc auuccacagg auguggggcu cacgauccug     1560

aaaggcgccg uacuguucgg gcucgacccc gcagugauua agguccgccg gaguccacug     1620

accuacggcg ugggugucuu gaacagguau guggaaggga aacauccccc ggagaagcug     1680

cucgugaagg auggcacucg cugguguacc gacguauuug auaaauucau cagcgccgac     1740

caauccgugg cccuggguga gcuggucaag cggagcuaca ccccagcaaa acccagucag     1800

uuggugaucg ucauuaauau cuauuccagc gaacacgaua acguguccuu uauuacugac     1860

cccggcguga agaaaugcgg gacgcugagg cucgaucuga ccggcaccag ugggacugcc     1920

guaccagcgc gccgggagau ccagacucuc augcaguucg gcgacaccga aauuaaggcc     1980

acggcaaucg auauugccac cagcaaaucc gucaaggugg guaucgacuu ucugaacuac     2040

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  2090
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt7)

<400>  2090
gggagaaagc uuaccaugcu ggccgugccc gagaugggcc uccaggggcu guacaucggu       60

agcuccccag aaaggagucc gguccccagc ccacccggcu ccccacggac ccaagagagu      120

ugcgggauug cacccuugac uccaagccag uccccgaagc ccgaagugcg cgccccacag      180

caggcgagcu ucuccguagu ggucgccauc gacuuuggca ccacgaguag cgguuaugca      240

uucuccuuug ccagcgaucc cgaggcaauu cacaugauga ggaaauggga agggggcgac      300

ccaggcgugg cccaucaaaa gacucccacc ugucugcucc ugaccccgga gggggcguuc      360

cacaguuuug guuacacugc ccgggauuau uaccaugacu uggaucccga ggaagcacgc      420

gacuggcugu auuucgagaa auuuaagaug aaaauccacu ccgccaccga ucucacgcug      480

aagacucagc uggaagccgu gaacggcaag accaugccag cacucgaggu cuucgcccau      540

gcgcugaggu uuuuccggga gcacgccuug caggaacugc gcgagcagag ccccucccuc      600

ccagaaaaag acacugugag guggguacug accgugcccg caauuuggaa gcaaccagcc      660

aaacaguuua ugcgggaggc agccuaccug gccggguugg ucagucgcga aaaugcggag      720

cagcuccuga ucgcacugga gccggaagcc gccagcgugu auugcaggaa gcuccggcug      780

caccaguugc uggaucucuc cggccgcgca cccggugggg gcaggcuggg cgagcggcgc      840

agcaucgaca guuccuucag gcaagcccgg gaacagcugc gcaggagccg gcauaguagg      900

accuucuugg uggaguccgg ggucggugaa cucugggcgg agaugcaggc cggcgaucgc      960

uacgugguag cagacugugg gggcgguacg guggaucuga cuguccacca acuggagcag     1020

ccacauggca cccucaaaga acuguacaag gccagcgggg gccccuaugg ggcagugggu     1080

guggacuugg ccuuugagca gcugcucugc cggauuuucg gcgaagacuu uaucgccacu     1140

uucaaaaggc agcgcccagc agccuggguc gaucugacca uugcguuuga ggcccggaag     1200

aggaccgcag ggccccaccg cgccggcgcc cugaacauca gcuugccguu cuccuuuauu     1260

gacuucuacc ggaagcaaag gggucacaau guggaaacug cacuccggcg caguagcgua     1320

aacuuuguga aaugguccag ccagggcaug cugaggauga guugugaggc gaugaaugag     1380

cuguuccagc caacggucuc cgggaucauu cagcauaucg aagcccuccu ggcacggccc     1440

gaggugcaag gcgucaaguu gcuguuucuc guagggggcu ucgccgaaag cgccgugcug     1500

cagcacgcag ugcaggccgc gcugggugcc cgcggguuga ggguggucgu gccccaugau     1560

gucggccuga ccauccucaa aggugcagug cuguuuggcc aggccccagg ggugguacgg     1620

gugcgcagga guccccucac uuauggcguc ggggugcuga accgguucgu cccaggcagg     1680

cacccgcccg agaaguugcu ggugcgcgac ggucggaggu ggugcaccga uguguucgag     1740

cgcuuuguag ccgcagaaca auccgucgcc cucggggagg aagugcggag gagcuacugu     1800

ccagcgcgcc ccggccagcg gagggugcug auuaaucugu auugcugugc cgcagaggac     1860

gcccgcuuca ucaccgaucc aggcguccgg aaaugcgggg cauugucccu ggaacucgag     1920

cccgccgacu gcggucagga uacugcgggc gccccgccag ggaggcgcga gauucgggca     1980

gccaugcagu uuggcgacac ggaaaucaag gugaccgccg uggauguaag cacuaacagg     2040

aguguccgcg cauccauuga cuuccugagc aauugaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  2091
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt7)

<400>  2091
gggagaaagc uuaccauggc cagggagaug accauccugg gcagcgcagu gcucacucug       60

uugcuggccg gguaccucgc gcagcaauau cugcccuugc caaccccgaa ggucauuggu      120

aucgaccugg gcacgacuua cugcuccgug gggguauucu uucccggcac cgguaaagug      180

aaggucauuc cagaugaaaa cgggcacauc aguauuccca gcaugguguc cuucaccgac      240

aaugaugugu augucggcua cgagagugug gaacucgccg acagcaaccc acagaauacu      300

aucuaugaug caaaacgguu uaucggcaag auuuucaccg ccgaggaacu ggaggcagag      360

aucgggcgcu accccuuuaa aguacugaac aagaauggua ugguggaguu cuccgucacg      420

agcaacgaaa cuauuaccgu guccccagaa uaugugggca guaggcuccu guugaagcug      480

aaagagaugg ccgaggcgua ccucgggaug ccggucgcca augcagugau cagcguaccc      540

gccgaauuug accugaagca gcggaacucc acuauugagg ccgcaaaucu ggccggcuug      600

aaaauccucc gcgugauuaa cgaaccaacc gcggccgcaa uggccuacgg ucugcauaag      660

gcagaugucu uccacgugcu ggugaucgac cucgggggcg gcacccugga ugucagcuug      720

cugaauaaac aaggggguau guuucucacg agggccauga guggcaacaa uaagcucggg      780

ggccaggacu ucaaccagcg gcuguugcag uaucucuaca aacagaucua ucaaacuuac      840

gguuuugugc ccucccgcaa ggaggaaauu cauaggcugc ggcaggccgu agagauggug      900

aagcugaauc ucacccugca ccagagcgcg caguuguccg uccugcucac uguggaggaa      960

caagaucgca aagagccaca uaguagcgac accgaacugc ccaaggauaa acuguccagc     1020

gcagacgacc acagggucaa caguggcuuc gggcggggcu uguccgauaa gaaaagcggg     1080

gagagucagg ugcuguucga aaccgagauc ucccgcaagc uguuugacac ucugaacgag     1140

gaucucuucc agaagauucu ggugccgauc caacagguau ugaaagaagg ucaccuggag     1200

aagacggaaa uugacgaggu gguccucgug ggcgggagca ccaggauccc ccggauccgc     1260

caggucauuc aggaauuuuu cggcaaagau ccaaauacua gcguggaccc cgaucuggcc     1320

gugguaaccg guguggccau ccaagcaggc auugacgggg gcuccuggcc acugcagguc     1380

agugccuugg agauccccaa caagcaucug cagaaaacca auuuuaacug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2092
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt7)

<400>  2092
gggagaaagc uuaccauggc cgcaaucggc gugcaccugg ggugcaccag cgccuguguc       60

gcgguguaca aggacgguag ggccggcgua guggcaaacg augccgggga ccgggucacu      120

cccgcagugg uggccuauuc cgagaaugaa gagauugucg gccucgcggc caaacagagu      180

cgcaucagga acauuagcaa uaccgugaug aagguaaaac aaauccuggg ucgguccagu      240

agcgauccac aggcacagaa guacauugcc gaauccaaau gcuuggugau cgagaagaac      300

gggaagcugc gcuaugaaau cgacacgggc gaggagacua aauucgucaa uccggaagau      360

guggccaggc ucauuuuuag caagaugaaa gagaccgcac auuccgugcu gggcagugac      420

gccaacgaug ucgugaucac cguacccuuc gacuuugggg aaaagcagaa aaaugcguug      480

ggugaggccg cacgggccgc aggcuucaac gugcugcgcc ucauucacga gccaagcgcc      540

gcccugcugg cguacgggau cggccaagau ucccccacug guaagagcaa uauucucguc      600

uuuaaacugg gcgggaccag uuugucccug agcgugaugg aagugaacuc cggcaucuau      660

aggguccuca guacgaauac ugacgauaac auugggggug cacauuucac cgagacucug      720

gcccaguacc uggccagcga auuucagcgg uccuucaagc acgacgugcg cggcaaugca      780

agggccauga ugaaguugac caacagcgcg gagguagcca aacauagucu cuccacccug      840

gggagcgcaa auuguuuucu ggauagucuc uaugaaggcc aggacuucga cugcaacgug      900

ucccgggccc gcuuugagcu guuguguagc ccacuguuca acaagugcau cgaggcaauc      960

aggggucucc uggaucaaaa uggcuucacg gccgacgaua uuaacaaagu cgugcugugu     1020

gggggcagcu cccggauccc caaguugcag cagcucauua aagaccuguu uccagccguc     1080

gaacugcuca auaguauccc gcccgaugag gugauuccaa ucggggcagc caucgaagcg     1140

gguauucuga ucggcaagga gaacuugcug guggaagaca gccucaugau ugagugcucc     1200

gcccgcgaua uccugguaaa ggggguggac gagagcggcg caaguagguu cacuguccug     1260

uuucccuccg guaccccauu gcccgcccgg cgccagcaca cucuccaagc cccgggcagc     1320

auuuccagug ugugucugga acuguacgag agcgauggga aaaauuccgc aaaggaagag     1380

accaaauucg cgcaggucgu gcuccaggac cuggauaaga aagaaaacgg cuugagggac     1440

auccuggccg ugcucaccau gaagcgggac gggagccugc acguaacuug cacggaucaa     1500

gagaccggca agugcgaggc aaucaguauu gaaaucgccu ccugaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  2093
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt7)

<400>  2093
gggagaaagc uuaccaugag cguggucggc cuggacgugg ggucccagag uugcuacauc       60

gccguagcaa gggccggugg cauugaaacc aucgcgaacg aguucagcga ucgguguacu      120

cccuccguga uuaguuuugg gagcaagaau cgcaccaucg gcgucgccgc caaaaaccaa      180

cagauuacgc acgcaaauaa cacugugucc aauuucaaga gguuucaugg ucgggcauuc      240

aacgacccau uuauccagaa agagaaggaa aaucucagcu augaucuggu gccguugaaa      300

aacgggggcg ucggcaucaa ggugauguac augggggagg aacaccuguu cuccguagag      360

cagauuaccg ccaugcuccu gaccaaguug aaagagacug cggaaaauag ucugaagaaa      420

cccgugaccg acugcgucau cagcgugcca uccuuuuuca cggaugccga gcgcaggagc      480

gugcucgacg cagcccaaau ugucggucug aacugucugc ggcucaugaa ugauaugacu      540

gccguggcac ugaacuaugg caucuacaag caggacuugc ccagucugga ugaaaaacca      600

cgcauuguag uguuugucga cauggggcau uccgccuucc aggugagcgc gugcgccuuu      660

aauaagggca aacucaaggu gcuggguacc gcauucgauc ccuuccuggg cgggaagaac      720

uuugacgaga aauuggucga gcacuucugu gccgaauuua agacuaaaua uaagcucgau      780

gcaaaaucca agaucagggc ccugcugcgg cucuaccagg agugcgaaaa gcugaaaaag      840

uugaugagua gcaauuccac cgaccugcca cucaacauug aguguuucau gaacgacaaa      900

gaugugagcg gcaagaugaa ucgcagucaa uuugaagaac ugugcgccga gcuguugcag      960

aaaaucgaag uaccgcucua uucccugcug gagcagaccc aucucaaggu ggaagacguc     1020

agcgcggugg agaucgucgg gggugcaacg aggauucccg ccgugaagga acggaucgcc     1080

aaauucuuug gcaaggauau uaguacuacc cugaacgcag acgaggccgu ggcgcgcggg     1140

ugugccuugc agugcgcaau ccugucccca gccuucaaag uaagggaguu uagcgugacu     1200

gaugcagucc ccuucccaau uagccucauc uggaaucacg acuccgaaga uaccgagggc     1260

gugcacgaag ucuuuagucg gaaccaugcc gcccccuuca gcaaggugcu gaccuuucug     1320

cgcagggguc cguucgaguu ggaagcauuc uacuccgacc cccaaggcgu gccauacccc     1380

gaggccaaaa ucgggcgguu uguagugcag aaugucagcg cgcagaagga uggcgagaag     1440

agucgcguga aagucaaggu gagggugaac acucacggga uuuucacgau cuccaccgcc     1500

agcaugguag aaaaaguccc aacugaggaa aaugagaugu ccagugaggc agacauggaa     1560

ugccucaacc aacggccccc agagaauccg gauaccgaca agaacgugca gcaggacaau     1620

agcgaagccg guacccagcc ccaagugcag acugaugccc agcagacguc ccaaagccca     1680

cccaguccag agcugaccuc cgaagagaac aaaauucccg acgcagauaa ggcgaaugag     1740

aaaaaggucg accagccgcc agaagccaag aaacccaaga ucaaaguggu gaacguagag     1800

cugcccauug aagcaaaucu cgucuggcag cugggcaagg auuugcugaa cauguauauc     1860

gagacugaag ggaaaaugau caugcaggac aagcucgaga aggagaggaa cgaugccaaa     1920

aaugccgugg aagaguacgu guaugaauuu cgcgacaagc uguguggccc auacgagaaa     1980

uucauuugcg aacaagauca ucagaacuuu cugcgguugc ugaccgagac cgaggacugg     2040

cucuaugaag agggugaaga ucaggcaaag caggccuacg ucgacaaacu ggaggagcuc     2100

augaagaucg gcacucccgu gaagguaagg uuccaagaag cggaggaacg cccaaaaaug     2160

uuugaggaac uggggcagcg guugcagcac uaugccaaga uugcagccga uuucaggaau     2220

aaagacgaga aguacaacca caucgacgag agcgaaauga aaaaggugga gaaauccguc     2280

aaugaaguga uggaguggau gaacaaugug augaacgccc aagcaaagaa gagucuggau     2340

caggacccgg ucgugcgcgc ccaggaaauu aaaacgaaga ucaaagagcu caauaacacc     2400

ugugagcccg uagugacuca gccaaagccc aaaauugaaa gcccaaagcu ggagcggacc     2460

cccaauggcc cgaacaucga uaagaaagaa gaggaccugg aggauaagaa uaacuuuggg     2520

gcggaaccac cccaucaaaa uggcgagugc uacccaaacg agaaaaacuc cgucaauaug     2580

gacuuggauu gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  2094
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt7)

<400>  2094
gggagaaagc uuaccauggc cgacaaggug aggcggcagc gccccaggcg gcgcgucugc       60

ugggcacugg uggccguacu ccuggcggau uugcuggccc ucagcgacac ccuggcagug      120

auguccgucg auuugggcag ugagagcaug aaaguggcca ucgugaagcc aggggucccg      180

auggaaauug ugcugaacaa agaguccagg cggaagacuc ccguaaucgu gacccucaaa      240

gaaaaugagc gcuucuuugg ugacagugca gccagcaugg cgauuaagaa cccaaaggcc      300

acgcugaggu acuuccaaca ucugcucggc aaacaggcag auaaucccca cgucgcccug      360

uaucaggccc gguuuccaga acacgaguug acuuucgacc cccagcgcca aaccgugcau      420

uuucagaucu ccagccagcu gcaguucucc ccagaggaag ugcucgggau gguccugaac      480

uacaguagga gccuggcaga ggauuuugcc gaacaaccga uuaaggacgc ggugaucacc      540

guacccgugu ucuuuaauca ggccgagcgg cgcgcagucu ugcaggccgc aaggauggcc      600

ggccucaaag ugcugcagcu gaucaacgau aauacugcca ccgcgcucuc cuauggugug      660

uuccggcgca aggacauuaa cacgacugca caaaauauca uguuuuacga uauggggagc      720

ggcaguaccg ucuguacuau ugugaccuau cagaugguaa aaaccaagga ggccggcaug      780

cagccacaac ugcagaucag gggugugggg uucgaccgga cguugggcgg gcuggaaaug      840

gagcuccgcc ugagggaacg gcuggccggc uuguucaacg agcagaggaa aggucagcgc      900

gcaaaggaug uccgggaaaa ucccagggcc auggcgaagc uccugcgcga ggccaaccgg      960

cugaaaacug ugcucuccgc aaaugccgac cacauggcac aaauugaggg gcugauggac     1020

gaugucgacu uuaaggccaa agugaccagg guggaguucg aggaauugug cgccgaucug     1080

uuugagcgcg uaccaggccc cgugcagcag gcacuccaga gcgccgaaau gucccuggac     1140

gagaucgagc aagucauucu ggugggcggg gcgacucggg ucccgagggu gcaggaagug     1200

uugcucaagg ccguagguaa agaggaacug ggcaagaaca ucaaugcaga ugaggccgcc     1260

gcaauggggg cgguguacca ggccgcagcc cugaguaagg ccuucaaagu caagcccuuu     1320

gugguccggg acgcaguggu guauccaauc cucguagagu ucacccgcga ggucgaggaa     1380

gaacccggca uucauagccu gaaacacaac aagagggugu uguuuucccg gaugggucca     1440

uacccccagc gcaaagugau caccuucaac agguacagcc acgauuuuaa uuuccauauu     1500

aacuauggcg accugggguu ucucggccca gaagaucugc gggucuucgg gagucaaaau     1560

cugacuacgg ugaaguugaa gggugugggc gacuccuuua aaaaguaccc ggauuaugag     1620

agcaaaggga ucaaggccca cuucaaccug gacgagagug gcguacucuc ccuggaccgc     1680

gucgaaagcg uguucgagac ccucguggaa gauagcgcgg aggaagaguc cacucugacc     1740

aaauugggua auaccauuag uagccuguuu ggcgggggca cuacgcccga cgccaaggag     1800

aacgggaccg auacugucca ggaagaggaa gaguccccag cagaaggcag caaggacgag     1860

cccggugaac agguggaacu caaagaggaa gccgaggccc caguagaaga ugggagucag     1920

cccccgccac ccgagcccaa gggcgacgca accccagagg gugaaaaagc caccgagaag     1980

gaaaauggcg auaaauccga ggcgcaaaag cccagcgaga aagccgaagc agggccagag     2040

ggcguggccc cggcacccga aggggagaag aagcagaaac cagccaggaa gcggaggaug     2100

gucgaagaga ucggcgugga gcuggugguc cuggacuugc ccgaucugcc agaagacaaa     2160

cucgcgcagu ccgugcaaaa gcugcaggau cucacucugc gcgacuugga gaaacaggaa     2220

cgggagaagg ccgcaaacag ucuggaagcc uucaucuuug agacgcagga uaagcuguac     2280

caacccgagu aucaggaagu aagcaccgag gaacagaggg aggagauuuc cgguaaacuc     2340

agcgccgcaa guacuuggcu ggaagacgag ggggugggcg ccaccacugu cauguugaag     2400

gaaaaacugg cggagcuccg caagcugugu cagggccucu ucuuucgggu ggaagagagg     2460

aaaaaguggc cggagcgccu guccgccuug gacaaucugc ugaaccauag cuccauguuc     2520

cucaaggggg cacggcugau cccagaaaug gaucaaauuu uuaccgaggu ggaaaugacg     2580

accuuggaga aagucaucaa ugaaacuugg gccuggaaga acgcaacccu ggccgagcag     2640

gccaaacucc ccgcaacuga gaagccagug cugcugagua aagacauuga agcgaagaug     2700

auggcccucg auagggaggu acaguaccug uugaauaaag ccaaguucac caagccccgc     2760

ccgcggccca aagacaagaa cgguacgagg gcagaaccac cccugaaugc cagcgcaucc     2820

gaucagggcg agaaagugau cccacccgcc gggcaaaccg aagacgcgga gccaaucagc     2880

gagccggaaa aggucgagac uggcagugaa cccggugaua ccgagccacu cgagcugggc     2940

gggcccggcg ccgaaccaga gcagaaagaa caguccacug ggcaaaagcg ccccuugaag     3000

aacgacgagc ugugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2095
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt7)

<400>  2095
gggagaaagc uuaccaugcc cgaggaaacc cagacucaag accagccaau ggaggaagag       60

gaaguggaga ccuucgccuu ucaggcagag aucgcccagc ugaugagccu cauuaucaac      120

acguucuacu ccaauaagga aauuuuucug agggaguuga ucaguaacag cuccgaugcg      180

cuggacaaaa uucgguauga aagucucacu gauccgagca agcuggacuc cggcaaagag      240

uugcacauca aucugauccc caacaagcaa gaucgcaccc ucaccauugu cgacacuggg      300

aucgguauga ccaaagccga ucugauuaau aaccugggca cgaucgcaaa gagcgggacu      360

aaggccuuca uggaggcacu ccaggccggc gcggacauuu ccaugaucgg ucaguuuggg      420

gugggcuucu acagugccua ucugguagca gaaaaaguga ccgucauuac uaagcauaau      480

gaugacgagc aguacgccug ggaaagcucc gccggcggga gcuuuaccgu gaggaccgau      540

acgggugagc caaugggccg ggggacuaaa gugaucuugc accugaagga agaccaaacc      600

gaguaucucg aggaacgcag gaucaaagag auugucaaga aacauaguca guucaucggc      660

uaccccauua cucuguuugu ggaaaaggag cgggauaagg aaguauccga cgacgaggca      720

gaggaaaaag aggauaagga agaggaaaaa gagaaggagg aaaaagagag cgaagacaag      780

ccagagaucg aggauguggg uuccgacgaa gaggaagaga agaaagaugg ggacaagaaa      840

aagaaaaaga agauuaaaga aaaguauauc gaucaggagg agcugaacaa aaccaagccc      900

aucuggaccc gcaauccaga cgauauuacu aacgaagagu acggcgaguu cuacaaaagu      960

uugacgaaug acugggagga ucaccucgcc gucaagcauu uuagcgugga aggccagcug     1020

gaguucaggg cgcuccuguu cgugccgcgg cgcgcccccu uugaccuguu cgagaacagg     1080

aagaaaaaga auaacaucaa auuguauguc cggcgcgugu uuauuaugga caauugcgaa     1140

gaacugaucc cagaauaccu caacuucauu agggguguag uggauuccga ggaccugccc     1200

cugaacauca gccgggaaau guugcaacag aguaagaucc ucaaagucau ucgcaagaau     1260

cuggugaaaa agugucugga gcucuuuacc gagcuggcag aagauaagga gaacuauaaa     1320

aaguucuacg aacaguuuuc caaaaauauc aaguugggga uucacgagga cagccaaaac     1380

aggaaaaagc ugagugagcu ccugcgguau uacacuuccg ccagcggcga ugaaauggug     1440

agccugaagg acuauugcac ccgcaugaaa gagaaucaga agcacaucua cuacauuacc     1500

ggggaaacua aagaucaggu cgcaaacucc gccuucgugg agagguugcg gaagcauggc     1560

cucgaaguaa ucuauaugau ugagccaauc gacgaguacu gugugcagca acugaaagaa     1620

uuugagggua agacgcuggu cagugugacc aaggaaggcc ucgagcugcc cgaagaugag     1680

gaggagaaaa agaaacagga agaaaagaaa acuaaguucg agaauuugug caaaaucaug     1740

aaggacauuc uggagaagaa agucgaaaag guggugguaa gcaacaggcu cgugaccucc     1800

ccguguugca ucgucaccag cacuuauggg uggacggcca auauggagcg cauuaugaaa     1860

gcgcaggcac ugcgggauaa caguaccaug ggcuacaugg ccgccaagaa acaccuggaa     1920

aucaaucccg accauuccau uaucgagacu uugaggcaga aggcagaagc cgauaagaac     1980

gacaaaagcg ugaaggaccu ggucauccuc cuguaugaga ccgcgcuccu guccaguggg     2040

uuuagcuugg aggauccaca aacucacgcc aaucgcauuu accggaugau caaacugggu     2100

cucggcauug acgaagauga ccccaccgca gaugacacgu ccgccgcagu gaccgaggaa     2160

augccacccc uggaggggga ugacgauacu agcaggaugg aagaggugga cugaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  2096
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt7)

<400>  2096
gggagaaagc uuaccaugga cagcuccaag cuggauagug gcaaagggcu ccacaucaac       60

cuggugccca auaagcagaa ccaaaccuug acuauugucg acaccaggau cgguaugacg      120

aaaacugauc ugauuaauaa ccucggcacc gugaccaaga gcgggacuaa agccuucaug      180

gaggcacugc aggccgacgc ggauaucucc augauuggcc auuuuggugu aggguucuac      240

agugccuauu ugguggcaaa gaaggucacc gugaucagca aacacaauaa cgacgaacag      300

uacacguggg aguccagcgc cggcggcucc uuuacugugc ggaccgauga augaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  2097
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt7)

<400>  2097
gggagaaagc uuaccaugcc cgaggaagug caccauggcg aggaagaggu cgaaaccuuc       60

gccuuucagg cagagaucgc ccaacugaug agccucauua ucaacacuuu cuacuccaau      120

aaggagauuu uucugaggga auugaucagu aacgcgagcg acgcccugga uaaaauucgg      180

uaugaguccc ucaccgaccc aaguaagcug gauagcggga aagaauugaa gaucgacauc      240

auuccgaauc cccaggagcg cacgcugacu cucguggaua ccgguaucgg caugaccaaa      300

gcagaccuga uuaacaaucu ggggacuauc gccaaguccg gcaccaaggc auucauggag      360

gcccuccagg cgggugccga uauuagcaug aucgggcagu uuggcguagg cuucuacucc      420

gcauaucugg uggccgaaaa agucguggug auuacgaagc acaacgacga ugagcaauac      480

gccugggaaa guagcgcagg ggguuccuuu acugucaggg ccgaccaugg cgagccaauc      540

gggcggggca ccaaagugau cuugcaccug aaggaagauc agacugagua ucucgaggaa      600

cgcaggguaa aagagguggu caagaaacau agccaguuca uugguuaccc caucacccug      660

uaucuggaaa aggagcggga aaaggagauu agugacgaug aggcggaaga ggaaaaaggg      720

gagaaggaag aggaggacaa agacgaugaa gagaagccaa aaaucgaaga cgugggcucc      780

gaugaggagg acgauagcgg caaggacaag aaaaagaaaa ccaagaaaau uaaggaaaag      840

uacaucgauc aggaggaauu gaauaaaacg aagcccaucu ggacucgcaa cccagacgau      900

auuacccaag aggaauacgg ggaguuuuau aaaucccuca cuaaugacug ggaggaucac      960

cuggccguga agcacuucag ugucgaaggu cagcuggagu uuagggcacu ccuguucauc     1020

ccgcggcgcg cccccuucga cuuguuugaa aacaaaaaga agaaaaauaa cauuaagcug     1080

uacgugaggc ggguauucau cauggacagc ugcgaugagc ucauuccaga auaucugaau     1140

uuuauccgcg gcguggucga cuccgaggau cugcccuuga acaucagcag ggagaugcuc     1200

cagcagagua aaauucugaa ggugauccgg aaaaauauug ugaagaaaug ucuggaacuc     1260

uucuccgagc uggcagaaga caaggagaac uacaagaaau uuuaugaagc cuucagcaag     1320

aacuugaaac uggggaucca ugaggauagu accaaucgca ggcggcucuc cgagcugcug     1380

cgcuaccaca ccagccaaag cggcgacgaa augacuuccu ugagugagua ugucagcagg     1440

augaaggaaa cgcagaaauc cauuuacuac aucaccggug agagcaagga acagguggcc     1500

aacagugcgu uuguagagcg ggugaggaag cgcggcuucg aggucgugua uaugacugaa     1560

ccaauugaug aguacugcgu ccaacagcuc aaagaauuug acgggaaguc ccuggugagc     1620

gugaccaaag agggccugga gcuccccgaa gaugaggaag agaagaaaaa gauggaagag     1680

uccaaggcaa aauucgagaa ucuguguaag uugaugaaag aaauccugga caagaaagua     1740

gagaagguga ccaucaguaa ccggcucguc agcuccccgu gcuguauugu gacuagcacg     1800

uaugggugga ccgccaauau ggaaaggauc augaaagccc aggcacugcg cgauaacagu     1860

acuauggguu acaugauggc caagaagcau cuggagauua aucccgacca cccaaucguc     1920

gagaccuugc ggcagaaagc ggaagccgau aagaacgaca aagcagugaa ggaccuggug     1980

guacuccugu uugagaccgc ccuccugucc agcggcuucu ccuuggaaga uccccaaacu     2040

cacaguaaua ggauuuaucg caugaucaaa cuggggcucg gcaucgacga ggaugaagug     2100

gcagccgagg agccaaacgc cgcagucccc gacgaaauuc caccgcugga gggugaugaa     2160

gacgccagcc ggauggagga aguggauuga ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  2098
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt7)

<400>  2098
gggagaaagc uuaccaugag ggcccugugg gugcucggcc ugugcugugu cuugcugacc       60

uucgggagcg ugcgggcaga cgaugaggua gacguggaug guacugucga agaggaccuc      120

ggcaaguccc gcgaagggag uaggaccgau gacgaggugg ugcagcggga agaggaggcc      180

auccaacugg auggcuugaa cgcgagccag auucgcgaac ugagggagaa auccgaaaag      240

uuugccuucc aggcagaggu caaucggaug augaaacuca ucauuaacag ucuguacaag      300

aauaaagaga ucuuucugcg cgaacucauu agcaacgccu ccgacgcacu ggauaagauc      360

agguugauca gccugacgga cgagaaugcc cucuccggua acgaagaacu gacugugaag      420

auuaaaugcg auaaggagaa aaaucuguug cacguaaccg acaccggggu gggcaugacu      480

cgggaggagc ucgucaagaa ccugggcacc aucgcgaaaa gugggacgag cgaguuccug      540

aauaagauga cugaggccca ggaagauggu caauccacca gcgagcucau uggccaguuu      600

ggggugggcu ucuauagugc auuucuggug gccgacaaag ucaucgugac uuccaagcau      660

aacaaugaca cccagcacau uugggaaagc gauuccaacg aguucagugu aaucgccgac      720

ccccgcggua auaccuuggg gaggggcacg acuauuaccc uggugcucaa ggaggaagca      780

agcgauuacc uggagcugga cacuaucaaa aacuugguca agaaauauuc ccaguuuauc      840

aauuucccaa uuuacgugug gagcaguaag accgaaaccg uggaggaacc gauggaggag      900

gaagaggccg cgaaagaaga gaaggaggaa uccgaugacg aggccgcagu cgaagaggaa      960

gaggaggaaa agaaacccaa gacuaaaaag guggagaaaa cgguauggga uugggaacuc     1020

augaacgaca ucaagccaau uuggcaacgg cccagcaagg agguggaaga ggaugaguau     1080

aaagccuuuu acaagaguuu cuccaaagaa agcgacgauc caauggcaua uauccauuuc     1140

accgccgagg gcgaagucac uuuuaagagc auucuguucg ugcccaccuc cgccccacgc     1200

gggcuguuug acgaguacgg uaguaaaaag agcgacuaca ucaagcucua ugucaggcgg     1260

guguucauca ccgaugacuu ucacgauaug augccgaaau accugaacuu cgugaagggc     1320

guaguggacu ccgaugacuu gccccugaau gucagccgcg aaacucucca gcagcauaaa     1380

cugcugaagg ugauuaggaa aaaguugguc cggaaaacgc ucgauaugau caagaagauu     1440

gcggacgaua aauauaacga caccuuuugg aaggaguucg ggacuaauau caaacugggc     1500

gugauugagg aucacaguaa ccgcaccagg cuggcaaagc uccugcgguu ucaguccagc     1560

caccauccaa ccgacaucac uuccuuggau caauacgugg aaaggaugaa agagaagcag     1620

gacaagaucu auuucauggc cgguaguagc cgcaaagaag ccgaguccag ccccuuugua     1680

gagcggcugc ucaagaaagg cuacgaagug auuuaucuga cggagccagu cgacgaauac     1740

uguauccagg cacugcccga guucgauggg aagagguuuc aaaauguggc caaagaaggc     1800

gucaaguucg acgagaguga gaagaccaaa gaaucccgcg aggcggugga aaaggaguuc     1860

gaaccguugc ugaacuggau gaaagauaag gcccucaaag acaagauuga gaaagcagug     1920

guaagccagc ggcugacuga gucccccugc gcccucgucg caagucagua cggguggagc     1980

gguaauaugg aaaggaucau gaaggcccag gccuaucaaa ccggcaagga uauuuccacu     2040

aacuacuaug caagccagaa aaagaccuuu gagaucaauc cacgccaccc ccugauucgg     2100

gacauguuga ggcggaucaa agaagaugag gacgauaaga cggugcugga ccucgccgug     2160

guccuguucg agaccgcgac ucugcgcagu ggguacuugc ugccagauac caaagccuau     2220

ggcgacagga ucgaacggau gcuccgccug ucccucaaca uugaccccga ugcaaaggug     2280

gaggaagaac cagaagagga gccggaagag acugccgaag acaccacgga ggauaccgaa     2340

caggacgagg augaggaaau ggacgugggu acugaugagg aagaggaaac cgccaaggag     2400

agcacugcag agaaagacga acugugagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  2099
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt7)

<400>  2099
gggagaaagc uuaccauggc cagggagcug cgggcacucc uguugugggg ccgcaggcug       60

cggccccucc ugcgcgcccc agcguuggcc gcagugcccg gggguaagcc gauccugugc      120

ccaaggcgga ccacugccca gcucggcccc cgcaggaacc cagcauggag ccugcaagcc      180

gggcggcugu ucuccaccca gacggcggaa gacaaagagg aaccccucca caguauuauc      240

agcuccacug agagugucca gggcagcacc uccaagcaug aauuucaggc cgagaccaaa      300

aagcuguugg auauuguggc acgcagccug uacuccgaga aagaaguauu caucagggag      360

cucauuagua augccagcga cgcccuggaa aagcugcggc acaaguuggu guccgauggu      420

caagcacucc cagagaugga gauccaucug cagacuaacg ccgaaaaagg gaccaucacg      480

auucaggaca cuggcaucgg caugacccag gaggaacugg ucagcaaucu cgggacuauu      540

gcgcgcagug guuccaaggc cuuucuggau gcauugcaaa accaggccga ggcaagcucc      600

aaaaucauug gccaguucgg ggugggcuuu uauagugccu ucaugguggc cgacaggguc      660

gaaguguaca gccgguccgc ggcaccgggu agccuggggu aucaguggcu cagugauggc      720

uccggcguau uugagaucgc cgaggccagc ggggugcgca ccgguaccaa gauuaucauc      780

caccugaaaa gugacuguaa ggaguucucc agcgaggcaa ggguccggga uguggugacg      840

aaauacagca auuuugucuc cuucccccug uauuugaacg gccgcaggau gaauacucuc      900

caagccauuu ggaugaugga cccaaaggau gugcgggaau ggcagcauga ggaauuuuac      960

agguauguag cgcaggccca cgacaagccc cgcuacaccc ugcacuacaa aacugaugca     1020

ccacugaaca uccggaguau uuucuaugug cccgacauga agccgagcau guucgacguc     1080

uccagggagc ucgggagcag uguggcccug uacucccgca aaguguugau ccaaaccaag     1140

gcaaccgaua uucugcccaa auggcuccgg uuuaucaggg gcgucgugga cagcgaggau     1200

aucccacuga aucugucccg cgaauugcuc caggagagug cccugauucg gaagcugagg     1260

gacguacucc agcagcggcu gaucaaguuc uuuauugauc aaagcaaaaa ggacgccgaa     1320

aaauaugcaa aguucuuuga ggauuacggu uuguucaugc gcgaaggcau cgugacugcc     1380

acggagcagg aggucaaaga agacauugcg aagcugcuca gguaugaguc cagcgcccug     1440

cccagugggc agcugaccuc cuugagcgaa uacgcauccc ggaugcgcgc cggcacuagg     1500

aacaucuauu accugugcgc cccaaaucgg caucucgcag agcacagucc cuacuaugag     1560

gcgaugaaga aaaaggauac cgaagugcug uuuuguuucg agcaguuuga cgaacucacc     1620

cuguugcauc ugcgcgaguu cgauaaaaag aaacucauca gcgucgaaac ugacauugug     1680

guggaccacu acaaggagga gaaguuugaa gauagguccc cagccgcaga gugccugagc     1740

gaaaaagaga cggaagaacu gauggccugg augcggaacg uauuggggag uagggugacc     1800

aaugucaagg ugacucugcg ccucgacacc cacccggcca uggucaccgu gcuggagaug     1860

ggugcagccc ggcauuuccu caggaugcaa cagcuggcga aaacucagga ggaacgcgcc     1920

caguugcugc aacccacgcu ggaaaucaac ccacggcacg cacucauuaa gaaacugaau     1980

caguugaggg ccuccgagcc cggccuggcc cagcuccugg uggaucagau cuaugaaaac     2040

gcaaugauug ccgcggggcu cguagacgau ccacgcgcca uggugggccg gcugaacgag     2100

uugcugguca aggcacugga gaggcauuga ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  2100
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt7)

<400>  2100
gggagaaagc uuaccauggg caagaucagc ucccugccca cccaacucuu caaaugcugu       60

uuuugcgacu uccugaaggu gaaaaugcac acuaugagua gcucccauuu guuuuaccug      120

gcccucuguc uguugaccuu cacgaguagc gcaacugccg ggccagagac ccugugcggu      180

gcggaacucg ucgaugcccu gcaguuugug uguggcgaca ggggguucua uuuuaacaag      240

ccgaccggcu acgguuccag cucccggcgc gcaccccaga cugggauugu agaugagugc      300

uguuucagga guugcgaccu gcggcgccuc gaaauguauu gugccccacu gaaacccgca      360

aagagcgcca gguccgugcg ggcgcagcgc cacaccgaua ugccaaagac gcagaaagag      420

guccauuuga agaaugccag caggggcagu gcaggcaaca aaaauuaccg gaugugagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  2101
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt7)

<400>  2101
gggagaaagc uuaccauggg cauccccaug gguaagagca ugcuggugcu ccugaccuuc       60

uuggccuuug cauccugcug uauugccgcg uacaggccaa gugagacucu gugcgggggc      120

gaacucgucg acacccugca guucgugugu ggggaucggg gcuuuuauuu cagccgcccg      180

gccuccaggg uaagucggcg cagcaggggu aucguggagg aaugcuguuu ucgguccugc      240

gacuuggcac ugcucgagac guacugugcc acucccgcaa aaagcgaacg cgaugucucc      300

accccaccca ccgugcugcc agacaacuuc cccagguauc caguggggaa guuuuuccaa      360

uacgauacuu ggaaacagag uacccagcgg cugcgcaggg gccucccggc ccuguugcgg      420

gcgcgcaggg gccacguccu ggccaaggag cucgaggcau uucgggaagc caaacgccau      480

aggccccuga uugcccugcc aacgcaggac cccgcacacg ggggugcccc acccgagaug      540

gcgagcaauc ggaagugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  2102
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt7)

<400>  2102
gggagaaagc uuaccaugaa cagcuucucc accagugccu uuggccccgu ggcauucagc       60

cuggggcucc uguugguccu gccagccgcg uuuccggccc ccgugccacc cggugaggac      120

uccaaggaug uagcagcccc acacaggcag ccccucacca guagcgaacg gaucgacaaa      180

caaauucgcu acauccugga uggcauuucc gcauugagga aggagacuug caauaaaagc      240

aacaugugug aauccaguaa ggaggcccug gcggaaaaua accucaaucu gccaaaaaug      300

gccgagaagg acgggugcuu ccagagcggc uuuaacgagg aaacgugucu ggugaagauc      360

auuacugguc uccuggaguu cgaagucuau uuggaguacc ugcagaaucg guuugagucc      420

agcgaagaac aggcacgcgc cgugcaaaug aguaccaaag ugcucaucca guuccugcag      480

aagaaagcca agaaccugga ugcaaucacc acuccggacc ccaccacgaa ugccuccuug      540

cucacuaaac ugcaggcgca aaaccagugg cugcaggaua ugaccacuca ucucauucug      600

aggagcuuua aggaguucuu gcaguccagu cugcgggccc uccgccaaau gugaggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  2103
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt7)

<400>  2103
gggagaaagc uuaccaugcc ccugcucugg cugaggggcu ucuugcuggc cagcugcugg       60

aucauugugc gguccagucc aaccccgggg agcgaggguc acuccgcagc ccccgacugu      120

ccaaguugcg cgcucgccgc acugcccaag gaugucccaa acagccagcc cgaaauggug      180

gaggccguga aaaagcauau cuugaauaug cugcaccuca aaaagcgccc agacguaacu      240

caaccggucc ccaaagcagc ccugcugaac gcgauuagga agcuccaugu gggcaaggug      300

ggggaaaaug gcuacgucga gaucgaagau gacauugguc ggcgcgccga gaugaacgag      360

cugauggaac agaccuccga gaucaucacg uuugcagaaa gcgggacugc caggaaaacc      420

uugcacuucg agauuuccaa ggagggcagu gaucugagcg ugguagaacg ggccgaggug      480

uggcucuuuc ugaaaguccc aaaggcaaau cgcaccagga cuaaagugac cauccggcug      540

uuccagcagc aaaagcaucc ccagggcucc uuggacacgg gggaagaggc cgaagaggug      600

ggucucaaag gcgagcgcag cgaacugcug cucagugaga aggucgugga ugcgaggaag      660

uccacuuggc acguauuucc agugagcucc aguauucagc ggcuguugga ccaggggaaa      720

agcucccugg auguccgcau cgccugugaa caaugccagg agagcggcgc aagucucgug      780

cugcugggua agaaaaagaa aaaggaagag gagggggaag gcaagaaaaa gggcgggggu      840

gagggcgggg ccggcgcaga cgaagagaaa gaacaguccc acaggcccuu cuugaugcuc      900

caggcccggc aaagcgagga ucauccgcac cgcaggcggc gcaggggucu ggagugugac      960

ggcaagguga acauuugcug uaaaaagcag uuuuucguca guuuuaagga uaucgggugg     1020

aaugacugga uuaucgcccc cuccggcuau caugcgaacu acugcgaagg ggagugucca     1080

agccacaucg cagguaccag cggcuccagu cugagcuucc acuccacugu gauuaaucau     1140

uaucggauga gggggcacag ccccuuugcc aaccucaaaa guugcugcgu accaaccaag     1200

cugcgcccca uguccauguu guacuaugac gauggccaga auaucauuaa aaaggacauc     1260

caaaacauga uuguggaaga gugugguugc agcugaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  2104
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt7)

<400>  2104
gggagaaagc uuaccaugga cggccugccc gggagggccc ucggugcagc cugccuguug       60

cugcucgcgg ccggcuggcu ggggccagag gcauggggca gcccgacucc cccacccacc      120

ccagccgcac ccccaccgcc cccaccccca gguucccccg ggggcaguca ggauaccugu      180

acgagcugcg gcggguuccg gcgcccggaa gaguugggua ggguggacgg cgauuuucug      240

gaagccguca agcggcacau ccucucccgc cugcaaauga gggggcggcc caacauuacu      300

caugcggugc caaaagccgc aaugguaacc gcccugcgca agcuccacgc cggcaaagug      360

agggaggacg gucgggucga aaucccccau cuggaugggc acgcaagucc aggcgccgac      420

ggccaggagc gcgugagcga gauuaucucc uucgcggaaa ccgauggguu ggccagcucc      480

agggugcggc uguacuuuuu cauuaguaau gaggguaacc agaaucucuu ugucgugcag      540

gcaagccugu ggcuguauuu gaagcuccug cccuacguac uggaaaaagg cucccgcagg      600

aaggugcggg ucaaggugua uuuccaagag caggggcaug gcgaccgcug gaacauggug      660

gagaaaaggg ucgaucucaa gcggagcggu uggcacacuu uuccacugac cgaagccauc      720

caggcauugu ucgagcgcgg cgaaaggcgg cugaaucucg acgugcagug ugauaguugc      780

caagagcugg ccguagugcc ggucuuugug gaccccgggg aagaguccca caggccauuc      840

guggucgugc aggcccgccu gggcgauagc cggcauagga uccgcaaacg gggguuggag      900

ugugacggua ggacgaaccu cugcugucgc cagcaguuuu ucauugacuu ccggcugauc      960

ggcuggaaug auuggauuau cgcgcccacu ggguacuaug gcaacuacug cgaagguucc     1020

uguccagcau aucuggccgg cguacccggg agugccagcu ccuuucacac cgcagugguc     1080

aaucaauaca ggaugcgggg ccucaacccg gggacuguga auagcugcug cauuccaacc     1140

aagcugagua ccauguccau guuguacuuc gacgaugagu auaacaucgu caaacgcgac     1200

gugcccaaua ugauugugga agaguguggc ugcgccugag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  2105
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt7)

<400>  2105
gggagaaagc uuaccauggc ccugagggug cuccuguuga ccgcacugac ucucugccac       60

ggcuucaacc uggacaccga gaaugccaug acguuucagg aaaacgcgcg gggguucggu      120

caaagcgucg ugcaguugca gggcucccgc guaguggucg gggcgcccca ggagaucgug      180

gcagccaauc aaaggggcag ucuguaccag ugugauuaua gcacugguuc cugcgaacca      240

auucggcucc aggugccggu cgaggcagug aacaugaguc uggggcugag ccucgccgcg      300

accaccuccc caccccagcu guuggccugu ggccccacug uacaucaaac cugcagcgaa      360

aauacguacg ugaagggccu guguuuucuc uucgggucca accugcgcca gcagccacag      420

aaauuucccg aggcacugag ggguugccca caagaggaca gugauaucgc cuucuugauu      480

gacggcagcg gguccaucau uccgcacgau uuucggcgca ugaaggaguu cgucagcacu      540

gugauggaac agcucaaaaa gaguaaaacc cuguuuuccc ugaugcagua uagcgaagag      600

uucaggaucc auuuuacuuu caaggaguuc caaaauaacc ccaauccacg gucccucgug      660

aagcccauca cccagcuguu gggccgcacc cacacggcca cugguauuag gaaagucgug      720

cgggaacugu uuaacaucac caauggggca cgcaagaacg ccuucaaaau ucucguagug      780

aucacugacg gcgagaaguu uggcgaucca cugggguacg aagacgucau ucccgaggcg      840

gauagggaag gugugauccg guaugugauu ggcgucgggg acgccuuccg cagugagaaa      900

agcaggcagg agcugaauac caucgcaucc aagccgcccc gggaucaugu guuucaggua      960

aacaauuucg aagccuugaa aaccauccaa aaccagcucc gcgagaagau uuuugcaauc     1020

gaaggcacuc agacggguag caguuccagc uucgagcacg aaaugaguca ggagggcuuu     1080

uccgccgcca uuaccagcaa cgggccacug cugagcacug ugggcuccua cgacugggcc     1140

gggggugucu uccucuauac caguaaggag aaaagcaccu uuaucaauau gacuagggug     1200

gauuccgaca ugaacgacgc auaccugggc uacgccgccg caauuaucuu gcggaauagg     1260

guccaaagcc uggugcucgg ggcgccccgc uaucagcaca ucggccuggu ggccauguuc     1320

cggcagaaca cggguaugug ggaaaguaau gccaacguaa agggcaccca gauuggggca     1380

uacuuuggcg ccucccugug uagcguggau gucgacucca augggaguac ugauuuggug     1440

cucaucggcg caccacauua uuacgagcaa accaggggug ggcaggucag cgugugcccc     1500

cugccacgcg gccgggccag guggcagugu gacgccgugc uguaugguga acagggccaa     1560

ccgugggggc gcuucggcgc agcccucacc guacuggggg augugaacgg cgacaaauug     1620

acugaugucg cgauuggugc ccccggggag gaagacaauc ggggcgcagu guaccuguuc     1680

cacggcacgu ccgggagcgg uaucagucca ucccauagcc agaggauugc cggcuccaag     1740

cucagucccc ggcugcagua uuuugggcaa agccuguccg gcggucagga uuugaccaug     1800

gacgggcugg ucgaucucac ugugggcgcc cagggccacg ugcugcuccu gcgcagccag     1860

ccaguauuga gggucaaagc aaucauggag uucaaccccc gggagguggc gcgcaaugug     1920

uuugaaugca acgaccaagu cgugaagggg aaggaggccg gugaagugag gguaugccug     1980

cacguccaga aaaguacccg ggaccgccuc agggagggcc agauccaguc cguggugacu     2040

uacgaucugg cacuggacag cgggcggccg cauuccaggg ccgucuucaa ugagaccaag     2100

aacagcacgc gccggcaaac ccagguguug ggccugacuc agaccuguga aacucucaaa     2160

cugcagcucc caaauugcau ugaggauccc guaaguccca ucgugcugag guugaacuuu     2220

agccuggucg guaccccacu guccgccuuc gggaaccucc gccccgugcu ggcagaagac     2280

gcccaacggu uguuuacggc gcuguuccca uuugagaaga auuguggcaa cgauaauauu     2340

ugccaggacg aucucaguau caccuucagc uuuauguccc uggacugucu cguggucggc     2400

gggccgaggg aguucaacgu gacuguaacc gugcgcaaug auggugaaga cagcuaccgg     2460

acucagguca ccuucuuuuu cccccuggau uuguccuaua ggaaagugag uacgcugcaa     2520

aaccagcgca gccagcgguc cuggaggcug gccugcgaga gugcaagcuc caccgaagug     2580

agcggcgccc ucaagaguac uuccuguagc auuaaucacc caaucuuucc cgagaacucc     2640

gaagucaccu ucaauauuac uuuugacgug gauagcaagg ccagucuggg gaacaaauug     2700

cugcucaagg caaauguaac cuccgagaac aauaugccac gcacgaacaa aaccgaguuc     2760

cagcuggaac ugcccgugaa guacgccguc uauauggugg ugacuagcca uggcgucagu     2820

accaaauacc ucaauuuuac ugcguccgag aacaccagcc gggugaugca acaccaguau     2880

cagguaucca accuggguca gaggagcuug ccgaucaguc ugguguuccu cgucccagug     2940

cgccugaauc aaacugugau cugggaccgg ccccagguca ccuuuagcga aaacuugucc     3000

aguacgugcc auaccaagga gaggcugcca agccacuccg acuuccucgc cgaacugcgc     3060

aaggcacccg ugguaaauug uagcauugcc gugugccaga ggauccagug cgauauuccg     3120

uuuuucggga uccaagagga auuuaacgca acucugaaag gcaaucucuc cuucgacugg     3180

uacauuaaga ccagucacaa ccaucuguug aucgucagca cugccgagau ccuguucaau     3240

gauuccgugu uuacccuccu gcccggccag ggggcguucg ugcggagcca gacggagacc     3300

aaagucgaac cauuugaggu gcccaaccca uugccccuga uuguagguag uuccgugggc     3360

gggcuccugc ugcucgcccu gaucacugca gccuuguaua agcugggcuu cuuuaaaagg     3420

caguacaagg acaugaugag cgaagguggc ccaccggggg ccgagcccca augaggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  2106
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt7)

<400>  2106
gggagaaagc uuaccauguu cagccugaag acccuccccu uucuguugcu gcuccacgug       60

cagaucucca aagccuuccc agucaguagc aaggagaaaa acacuaagac cgugcaagac      120

uaccuggaaa aauuuuauca guugccgucc aaucaguacc agaguacgag gaagaacggc      180

acuaauguaa uuguggagaa gcugaaagaa augcaacggu ucuuugggcu caacgucacc      240

gguaagccca augaggaaac ccuggauaug augaaaaagc cacgcugcgg cgugcccgac      300

agcgggggcu ucaugcugac uccagguaac cccaaauggg agaggaccaa ucucacguau      360

cggauccgca acuacacucc acagcugucc gaggcagaag uggagagggc cauuaaggau      420

gcguuugaau uguggagcgu cgccuccccg cugaucuuca cccggauuag ucagggggag      480

gcagacauca auaucgccuu uuaucagcgc gaucauggcg acaacagccc cuucgauggc      540

ccaaauggga uucucgcaca cgccuuucaa cccggucagg gcaucggggg cgacgcgcau      600

uucgaugccg aggaaacuug gaccaacacc uccgcaaauu acaaccuguu ccugguggcc      660

gcccacgagu uuggucauag cuuggggcuc gcacacaguu ccgacccagg cgcccugaug      720

uaucccaauu acgcguucag ggaaacgagc aacuacuccc ugccgcagga ugacauugau      780

ggcauccagg ccauuuaugg gcucaguagc aaccccaucc aaccaacugg ucccuccacc      840

ccaaaacccu gugacccaag ccugacuuuu gacgcaauua ccaccuugcg gggcgagauc      900

cuguucuuua aggaucgcua cuucuggagg cggcacccgc agcuccagcg cguagaaaug      960

aauuuuauca gucuguucug gcccucccug ccaacuggga uucaagccgc auaugaggac     1020

uuugauaggg acuugaucuu ccucuuuaag ggcaaccagu acugggcccu gagcgguuau     1080

gauauucugc agggcuaccc caaagacauc aguaauuaug gguucccauc cagcgugcag     1140

gccauugaug cggcagucuu uuaccggagc aagacguacu ucuucgugaa cgaccaauuu     1200

uggcgcuaug auaaucagag gcaguucaug gagcccggcu acccgaaauc caucaguggg     1260

gccuuuccag guaucgaaag caagguggac gccgucuucc agcaagagca cuuuuuccau     1320

guguuuuccg gcccccggua uuacgcauuc gaucucauug cccagcgcgu aaccagggug     1380

gcgcggggga acaaauggcu gaauugcagg uauggcugag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2107
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt7)

<400>  2107
gggagaaagc uuaccaugag ccuguggcag ccccucgugc uggucuugcu ggugcucggc       60

ugcuguuucg ccgcaccaag gcaacggcag uccacccugg uauuguuucc gggggaccug      120

cgcacuaacc ucaccgauag gcagcuggcc gaggaauacc uguaucggua cgguuauacg      180

cgcguggcgg agaugagggg cgaaaguaag agccucgggc ccgcccuguu gcugcuccag      240

aaacaacugu cccugccaga gacuggcgaa uuggacagug caacccucaa ggccaugcgg      300

acccccaggu gcgguguccc agaucugggg agguuccaga cuuuugaggg cgaccugaaa      360

uggcaccauc acaauaucac cuacuggauu cagaacuaua gcgaggaucu cccccgggca      420

gugaucgacg augccuucgc gcgcgccuuu gcacuguggu ccgccgugac gccauugacu      480

uucaccaggg ucuacagccg ggacgccgau auugugaucc aguuuggcgu agcagaacau      540

ggggacgguu auccguucga uggcaaggac gggcugcucg cccacgcguu ucccccaggc      600

cccgguauuc aaggggaugc ccauuucgac gacgaugagc uguggucccu gggcaaaggc      660

guggucgugc caacucgcuu ugggaaugca gacggugccg caugucacuu ccccuucauc      720

uuugaaggca ggaguuacag cgccugcacc accgaugggc gguccgacgg cuugccgugg      780

uguagcacga cugccaacua cgauaccgac gaucgcuucg guuuuugccc cagugagagg      840

cucuauacuc aggacggcaa ugcggauggg aagccauguc aguuccccuu uaucuuccag      900

ggccaauccu acagcgcaug caccaccgac gggcgguccg augguuaucg cuggugugcc      960

acuacggcca acuacgacag ggacaagcug uuuggcuucu gcccaacccg ggcagauagu     1020

acugugaugg gcgggaauag cgccggugag cugugcgucu uucccuucac cuuucucggc     1080

aaagaauauu ccaccuguac uagcgagggg aggggcgacg ggcgccugug gugcgcgacg     1140

accaguaacu ucgauuccga caagaaaugg ggcuuuuguc cagaucaggg uuacagcuug     1200

uuccuggugg ccgcacacga guucgggcau gcccucggcc uggaccacag uuccguaccg     1260

gaagcacuga uguaucccau guaccgguuu acugaagguc cacccuugca uaaggaugac     1320

gugaauggca uuaggcaccu cuacgggcca cgccccgagc cggagccacg gccacccacc     1380

accacuacgc cccagcccac cgccccaccg acugucugcc ccaccggccc acccacugug     1440

cacccaagcg aaaggcccac cgccgggccg acgggcccac ccagcgcagg uccaaccggg     1500

cccccgacug ccggccccuc caccgcgacu accgugccac ugagucccgu cgaugacgcc     1560

uguaacguga auaucuucga ugcaauugcc gagaucggca accaacugua ucucuuuaaa     1620

gacgggaagu acuggcgcuu cagcgaaggu cggggcucca ggccacaggg gcccuuucug     1680

auugccgaua aauggccagc auugccgcgg aagcuggaca gcguauucga ggaacgccuc     1740

aguaagaaac uguuuuucuu uuccggccgc cagguguggg ucuauacggg ugcgagcgug     1800

cuggggcccc ggcgcuugga caagcugggc cucggcgccg augucgcaca ggugaccggg     1860

gcccugaggu ccggucgggg caaaaugcuc cuguucagug ggcgcagguu guggcgguuu     1920

gacgugaagg cccaaauggu agauccaagg agcgcauccg agguggaccg cauguucccc     1980

ggcgucccac uggauacuca ugacguguuc caguaccggg agaaagccua uuuuugccag     2040

gauagguucu acuggcgcgu cagcagucgg uccgaacuca aucaggugga ccaagugggu     2100

uauguaaccu acgauauccu gcaguguccc gaggacugag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  2108
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt7)

<400>  2108
gggagaaagc uuaccaugca ccccggcgug cuggccgcau uccucuuucu gagcuggacc       60

cauugcaggg ccuugccacu gccguccggg ggugacgagg augaccucag ugaagaggau      120

cugcaguucg cggaacggua cuugcgcagc uauuaccacc ccacuaaccu ggccggcauc      180

cucaaggaga augcagccuc caguaugacc gaaaggcugc gggagaugca gagcuuuuuc      240

gggcuggagg ucacgggcaa acucgacgau aacacucugg acgugaugaa gaaaccacgc      300

ugugguguac ccgauguggg ggaauauaau gucuuuccaa ggaccuugaa gugguccaaa      360

augaaccuga ccuaccggau ugugaauuau acucccgaca ugacccauag cgagguggaa      420

aaggcauuca agaaagccuu uaaggucugg uccgauguga cgccacucaa cuucacucgc      480

cugcacgacg gcaucgcgga uauuaugauc aguuuuggca uuaaagagca uggggacuuc      540

uacccguuug auggucccag cggccuguug gcccacgcau ucccacccgg gccaaauuau      600

ggcggugacg cccacuucga cgaugacgag accuggacuu ccagcaguaa gggguacaac      660

cucuuucugg uagccgcaca ugaguucggc cacucccugg gccucgauca uagcaaagac      720

cccggggccc ugauguuucc gaucuacacc uauaccggua agucccacuu cauguugccc      780

gaugacgaug ugcaaggcau ccagagucug uacgggccag gcgacgagga ucccaaucca      840

aaacacccca agacgccaga caagugcgau ccgagccucu cccuggacgc gauuacuagc      900

cugaggggug aaaccaugau cuuuaaagac cgguucuuuu ggcgcuugca uccccagcaa      960

gucgaugccg aacucuuccu gacuaagagu uuuuggccag aacugcccaa caggauugac     1020

gcagccuaug agcacccauc ccaugaucuc aucuucauuu uucggggccg caaauucugg     1080

gcacugaaug gguacgacau cuuggagggc uaucccaaga aaauuagcga acuggggcuc     1140

ccgaaggagg ugaagaaaau cagugccgcc gugcacuuug aagauaccgg uaagacccug     1200

cuguucuccg gcaaccaggu cuggagguac gacgauacua aucauaucau ggacaaagau     1260

uauccacggu ugauugagga agacuucccc gggaucggcg auaaggugga cgcgguauac     1320

gagaaaaacg guuacauuua cuuuuucaau ggccccaucc aguuugagua uagcauuugg     1380

agcaaccgca ucgugagggu caugccagca aacuccaucc ucugguguug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2109
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt7)

<400>  2109
gggagaaagc uuaccaugga gacccccaac acuaccgaag acuacgauac gacuaccgag       60

uucgacuaug gcgaugccac cccaugccag aaggugaaug aaagggcauu uggggcccaa      120

cugcucccgc cccuguacag cuuggucuuc gugaucgguc ugguaggcaa cauucucgug      180

guccuggugu uggugcagua uaaacggcug aagaauauga cuuccaucua ccuccugaac      240

cuggcgauua gugaccuccu guuuuuguuc acccugccau uuuggaucga uuauaaacuc      300

aaggacgauu gggucuucgg ggacgccaug uguaaaauuc ugagcggcuu uuacuauacg      360

ggucuguacu ccgagaucuu cuuuaucauu uugcucacua ucgaucgcua ccuggcaauu      420

gugcacgccg uauucgcacu gagggcccgg accgugacuu uuggggucau caccaguauu      480

aucauuuggg cgcucgccau ccuggcaagc augcccggcu uguauuucuc caagacccag      540

ugggaauuua cgcaucacac uugcagccug cauuuuccac acgagucccu ccgcgagugg      600

aagcuguucc aggcccugaa auugaaucuc uuuggccugg ugcugccccu ccuggugaug      660

aucauuuguu acaccgggau cauuaagauc uugcugaggc ggccaaacga gaaaaagagu      720

aaagccgucc gccucauuuu cgugaucaug aucauuuucu uccuguuuug gacuccguau      780

aaucugacca ucuugauuag cguauuccaa gacuuucucu ucacccauga augcgaacag      840

uccaggcacc uggaucuggc agugcagguc acugagguga ucgccuacac gcacuguugc      900

gugaaccccg ucauuuaugc guuugugggu gagcgguucc gcaaguaccu caggcagcug      960

uuucaucggc gcguagccgu gcacuugguc aaauggcugc cauuccucag cguggacagg     1020

cuggaacggg ucaguuccac cagccccucc acuggcgagc augaacugag ugcaggguuc     1080

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  2110
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt7)

<400>  2110
gggagaaagc uuaccaugag gacccuggcc ugccuccugu ugcugggcug uggguaccuc       60

gcacacgugc uggccgagga agcggagauc ccccgggaag ucauugagcg cuuggccagg      120

agccagaucc auuccauucg ggaccugcaa cgccuccugg aaaucgauag uguggguagc      180

gaggacuccc uggauaccag ucucagggca cacggcguac augccacuaa gcacgugcca      240

gagaaacggc cgcugcccau ucgcaggaag cggagcaucg aagaggcagu cccagccgug      300

ugcaaaacgc gcacugugau cuaugaaauu cccagguccc aggucgaccc aaccagcgcg      360

aacuucuuga ucuggccccc auguguggag guaaagcggu gcaccgggug uugcaauacu      420

uccaguguga aaugucagcc gagccgcguc caucacaggu ccgugaaggu ggccaagguc      480

gaguacgugc ggaaaaagcc caaacugaag gaaguacagg ugcgccucga ggaacaccug      540

gagugcgcau gugccaccac gagccugaac ccagauuaua gggaagagga cacuggccgg      600

ccccgcgaga gugguaaaaa gaggaaacgg aagagguuga agccaaccug aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  2111
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt7)

<400>  2111
gggagaaagc uuaccaugaa caggugcugg gcccuguucc ucagccugug uugcuacuug       60

cggcuggugu ccgcagaggg cgaccccauc ccagaggaac ucuaugaaau gcugagugau      120

cacagcauuc gcuccuuuga cgauuugcag aggcugcucc auggggaccc gggugaggaa      180

gauggcgccg agcuggaccu gaauaugacc cggagucaca gcgggggcga gcucgaaucc      240

cuggcgcgcg guaggcggag cuuggggucc cugacuaucg ccgagcccgc aaugauugcc      300

gaauguaaga cccgcacgga ggucuucgag aucaguaggc ggcucauuga ucgcacuaac      360

gcaaauuuuc ugguguggcc acccugcgua gaagugcaaa gguguagcgg cugcuguaac      420

aaucggaacg uccagugccg cccaacccag gugcagcuga ggcccgugca aguccggaaa      480

aucgagaucg ugcgcaagaa accaauuuuc aagaaagcca ccguaacuuu ggaagaccau      540

cucgcgugua agugcgagac cguggccgca gccaggccgg ucacgcgguc ccccggcggg      600

agccaggaac agcgcgccaa gacuccacag accaggguga cuauccggac cgugaggguc      660

cgccggcccc caaaagguaa gcacaggaaa uuuaagcaua cccacgauaa aacggcacug      720

aaggagacuc ugggcgccug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  2112
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt7)

<400>  2112
gggagaaagc uuaccaugag ccuguucggc cuccuguugc ugaccuccgc ccucgcaggg       60

cagaggcaag guacucaggc cgagaguaac cugagcucca aguuucaguu caguagcaau      120

aaagaacaga acggcgugca agacccccag cacgagcgga ucauuaccgu cuccacgaau      180

gggagcaucc auuccccacg cuuuccgcac acuuacccca ggaacaccgu guugguaugg      240

cggcuggugg cggucgaaga gaaugugugg auucagcuca ccuucgauga acgcuuuggc      300

cuggaggacc cagaggauga caucugcaag uaugauuucg uggaagucga ggaacccagu      360

gacgguacua uucuggggag gugguguggc agcggcaccg ugccagggaa acagaucucc      420

aaggguaacc aaauccggau ucgcuuugua agcgaugagu acuuccccag ugagccaggc      480

uuuugcaucc auuauaauau ugugaugccg caguucacgg aagccgucuc ccccagcgug      540

cucccacccu ccgcacugcc auuggaccug cucaacaaug ccaucacugc auuuaguacc      600

cuggaggauc ugauuaggua cuuggaaccc gagcgguggc agcucgaccu ggaagaucug      660

uaucgcccga cuuggcagcu ccuggggaaa gccuucgugu ucggcaggaa aagccggguc      720

guggacuuga accugcucac cgaggaggua cgccuguacu ccuguacccc caggaauuuu      780

agcgugagua uccgggagga acugaagcgc acggauacua uuuucuggcc agguugcuug      840

cucgucaaga gguguggggg caacugcgcg uguugccugc acaauuguaa cgaaugccaa      900

ugcgugcccu ccaaggugac caaaaaguau caugaggucc ugcagcuccg gccaaaaacu      960

ggcgugcgcg ggcugcacaa gagcuugacc gacguagccc uggaacacca ugaggagugu     1020

gacugcgugu guagggguag uaccggcggg ugaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  2113
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt7)

<400>  2113
gggagaaagc uuaccaugca caggcugauc uucguguaca cccucauuug cgccaacuuu       60

uguagcugcc gggacacuuc cgcaacgccc cagagugcca gcaucaaggc gcugcgcaau      120

gccaacuuga ggcgggauga ccuguaucgc agggaugaga ccauucaagu caaaggcaau      180

ggguacgugc aguccccacg guucccgaac aguuaucccc gcaaucuccu guugacuugg      240

aggcugcaua gccaggaaaa cacccggauc cagcucguau uugacaauca auucggucug      300

gaggaagcag agaacgauau uugucgcuac gacuuugugg aagucgagga uaucuccgag      360

accagcacua ucauuagggg ccgguggugc gggcacaagg aagugccacc ccgcaucaaa      420

uccaggacca aucagauuaa gaucacguuc aaaagugacg auuauuuugu ggccaagcca      480

ggcuucaaga uuuacuauag ccugcucgag gacuuucagc ccgcagccgc guccgaaacu      540

aacugggaga gcgucaccag uuccaucagc gguguguccu acaauagucc aagcguaacu      600

gauccgaccc ugauugccga cgcauuggau aaaaagaucg ccgaguucga caccguggaa      660

gaccugcuca aauacuuuaa ccccgagucc uggcaggaag aucuggagaa uauguaucug      720

gacacgccac gguaccgcgg gaggagcuau caugaucgga agaguaaagu cgacuuggau      780

cgccucaacg acgaugccaa gagguacucc uguacucccc ggaauuauag cgugaacauc      840

agggaggaac ugaaacuggc aaacgugguc uucuucccac gcugccuccu ggugcaacgg      900

uguggcggca auugcgggug ugguaccgua aacuggagga guugcacuug caauuccggc      960

aagaccguga agaaauacca cgaggucuug caguuugaac ccgggcauau uaagcgccgg     1020

ggcagggcca aaaccauggc gcugguggac auccagcucg aucaccacga gcgcugugac     1080

ugcauuugua gcagccggcc gcccagguga ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  2114
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt7)

<400>  2114
gggagaaagc uuaccauggu gacccacagc aaguuccccg ccgcaggcau guccaggcca       60

cuggacacca gucuccggcu gaaaacuuuu agcuccaaga gugaguacca guuggucgug      120

aacgccguac gcaaacugca agaaagcggg uucuauuggu ccgcggugac ggguggcgag      180

gccaaucucc uguugagcgc agaaccggcc gggacuuuuc ugaucaggga uuccagugac      240

cagcggcauu ucuuuacccu cagcgucaag acccaguccg gcacuaaaaa ccugcgcauu      300

cagugcgagg gugggagcuu cagucugcaa uccgauccca ggagcaccca gccagugccc      360

cgguuugacu gugugcucaa gcugguccac cauuacaugc cacccccagg cgcaccgucc      420

uuccccaguc cacccacgga accaagcucc gaggugcccg agcagccgag cgcccagccc      480

uugccaggca gucccccacg cagggcguau uacaucuauu ccggggguga aaagauuccc      540

cugguacuca gccggccacu gaguuccaau guggccacuc ugcaacacuu gugccgcaaa      600

accgucaacg gccaucucga uagcuacgag aaggugacuc agcugccggg gcccaucagg      660

gaauuucugg accaguauga ugcaccacuc ugaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  2115
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt7)

<400>  2115
gggagaaagc uuaccauggu gcccagcgcc ggccagcugg cacucuucgc ccuggggauc       60

gucuuggcgg ccugccaagc acuggagaac uccaccaguc cacucagcgc cgacccgccc      120

guggcagccg cgguaguguc ccacuuuaau gauuguccag acagucauac ucaguucugc      180

uuucacggua ccuguagguu ccugguccag gaagauaagc ccgccugcgu gugucauagc      240

ggcuacgugg gggcacggug cgagcacgcc gacuugcugg ccgucguggc agccucccag      300

aaaaagcaag cgauuacggc ccucguagug gucagcaucg uggcacuggc cgugcugauu      360

aucacuugug uccucauuca uugcugucag gugcgcaaac acugcgaaug gugcagggca      420

cugaucuguc ggcacgagaa gccauccgcc uugcugaaag gccgcaccgc cugcugucau      480

agugaaaccg uagugugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  2116
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt7)

<400>  2116
gggagaaagc uuaccaugcc cccaagcggc cugaggcucc ugccguugcu gcucccccug       60

uuguggcugc ucgugcugac cccagggcgg cccgccgcag gucuguccac uugcaagacc      120

aucgacaugg agcucgucaa acgcaagagg auugaagcca uccggggcca gauucugagu      180

aaauugcgcc uggcgagccc acccucccaa ggggaggugc caccgggccc ccucccagaa      240

gccguacugg cacuguacaa caguacgagg gaucgggugg ccggugagag cgcagaaccc      300

gagccagagc ccgaagccga cuauuacgcg aaggagguca cucgcguguu gaugguggaa      360

acccacaaug agaucuauga uaaauucaag caguccaccc auagcauuua cauguuuuuc      420

aacacuuccg agcucaggga agccgucccg gagcccgugc ugcugagucg ggcagaacuc      480

cgccuguuga ggcugaagcu caaaguagag cagcacgugg aacuguauca gaaguacagc      540

aauaacuccu ggcgguaucu gagcaaucgc uugcucgccc caagugacuc ccccgagugg      600

cugagcuuug augucaccgg gguggugagg caauggcugu cccggggcgg cgagaucgaa      660

ggguuccgcc ucagugccca uuguagcugc gacuccaggg auaacacgcu gcaggucgac      720

aucaaugguu uuacuaccgg ccggcgcggg gauuuggcaa cuauucacgg caugaacagg      780

ccauuccugc uccugauggc cacgccccug gagcgggcgc agcauuugca gagcaguagg      840

caccgccggg cccucgacac caauuacugu uuuuccagca ccgagaaaaa cugcugugug      900

aggcaacugu acaucgauuu ccgcaaggac cuggguugga aauggauuca cgaaccaaag      960

ggguaucaug caaauuuuug ccucggcccg ugucccuaca ucuggagucu ggauacucag     1020

uauuccaaag uauuggcccu guacaaccag cacaauccag gcgcaagcgc cgcccccugc     1080

ugugugccac aggcgcucga accccugccg auugucuauu acguggggcg gaagccaaag     1140

guggagcaac ugagcaacau gaucgucagg uccugcaaau gcaguugagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  2117
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt7)

<400>  2117
gggagaaagc uuaccaugca cuacugcgug cugagcgccu uccucauccu gcauuugguc       60

accguggcac ugucccucag uacuuguagc acccuggaca uggaucaguu uaugaggaag      120

cggauugagg ccauccgcgg ccaaauuuug uccaaacuga agcucacgag ucccccagaa      180

gacuauccgg agcccgaaga gguaccaccc gaagugauca gcauuuacaa cuccacuagg      240

gaucugcugc aggagaaagc gagccggcgc gccgcagccu gcgagaggga acgguccgac      300

gaggaauauu acgcaaagga ggucuauaaa aucgauaugc cacccuucuu uccaagugag      360

aaugccaucc cgcccaccuu cuaccgccca uauuuuagga uugugcgguu cgacgugagc      420

gcgauggaaa agaacgccuc caaucucguc aaggcagagu uucgcguguu caggcugcag      480

aaccccaaag cccggguacc agaacagcgc aucgaguugu accaaauucu caagagcaaa      540

gaucugacca gucccacuca gagguacauc gacuccaagg uggucaaaac ccgggccgaa      600

ggggaguggc ugagcuuuga ugugacggac gcagugcacg aguggcugca ucacaaggau      660

cgcaauuugg guuucaaaau uucccuccau uguccgugcu guacuuuugu ccccaguaac      720

aauuauauca uuccaaacaa gagcgaggaa cuggaagcca gguucgcggg caucgacggg      780

accuccacuu acaccagcgg cgaucagaag accaucaaaa guacgcggaa gaaaaauucc      840

gguaagacuc cccaucugcu ccugauguug cugccaagcu aucgccucga gagucagcaa      900

accaacaggc ggaaaaagag ggcccuggac gcagccuacu gcuuccgcaa ugugcaggac      960

aacuguugcc ugcggcccuu guauauugau uuuaagaggg accucgggug gaaauggauc     1020

cacgaaccaa agggcuacaa ugcaaacuuc ugugccggcg ccugcccgua ucuguggucc     1080

agcgauacuc agcacagccg cguacugucc cucuacaaua ccauuaaccc cgaggcgagu     1140

gcaagcccau gcuguguguc ccaggaccug gagcccuuga ccauccugua cuauauuggg     1200

aaaacuccaa agaucgaaca acucagcaac augaucguca aaaguugcaa guguuccuga     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  2118
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt7)

<400>  2118
gggagaaagc uuaccaugaa gaugcaucug cagagggccc ucgugguccu ggcauugcug       60

aacuucgcca ccgugagccu cucccugagu acuugcacca cguuggacuu uggccacauc      120

aaaaagaaac ggguagaggc gauucgcggg caaauccuga gcaagcucag gcugacuucc      180

ccacccgaac cgaccgugau gacccacguc cccuaccagg ugcuggcccu cuauaauagu      240

acucgggagc uguuggaaga gaugcauggu gaacgcgagg agggcuguac ccaggaaaac      300

acggagagcg aauacuaugc aaaagagauu cacaaguucg auaugaucca ggggcuggcc      360

gagcauaaug aacucgcagu gugcccaaag ggcauuacuu ccaaagucuu uagguucaac      420

gugagcuccg uagagaagaa ucggaccaac cuguuucgcg ccgaguucag ggugcugcgg      480

guccccaauc caaguagcaa acgcaacgaa caaaggaucg aauuguuuca gauccuccgg      540

cccgacgagc acauugcgaa gcagcgcuac aucgguggga aaaaucugcc aacuaggggc      600

accgccgagu ggcuguccuu cgaugugacc gacacggugc gggaauggcu ccugcgcagg      660

gagagcaacu ugggccugga aauuaguauc cacuguccgu gccauacuuu ucagcccaau      720

ggggauauuc ucgagaacau ccacgaaguc auggagauua aguucaaagg uguggacaau      780

gaggaugacc auggccgcgg ggaucugggc cggcugaaga agcaaaaaga ccaccacaac      840

ccacauuuga uccucaugau gauuccccca cacaggcugg auaaucccgg ucaagggggc      900

cagcggaaga aaagggcacu ggacaccaac uauuguuuuc gcaaccucga agagaauugc      960

uguguacggc cgcuguacau cgauuucagg caggacuugg gcuggaagug ggugcaugaa     1020

cccaaagggu auuacgccaa cuucugcucc gguccauguc ccuaccugcg cagcgccgac     1080

acuacccacu ccaccguccu cggccuguau aauacucuga acccagaggc aagugccagc     1140

cccugcugcg ugccacagga uuuggaaccg cucacgaucc uguacuaugu ggggcggacc     1200

cccaaggucg agcagcuguc caauauggug guaaagagcu guaaaugcag uugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2119
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt7)

<400>  2119
gggagaaagc uuaccauggc ccccguggca gucugggccg cgcuggccgu gggccucgag       60

cugugggcag ccgcacacgc cuugccagcg cagguagccu ucaccccgua cgcacccgaa      120

ccagggagca cuugcaggcu gcgggaguau uacgaccaaa ccgcccagau guguugcucc      180

aaguguaguc ccggucagca ugccaaagug uuuugcacga agacuagcga uaccgucugu      240

gacuccugcg aagauaguac cuauacucag cucuggaacu gggugccaga gugucugagc      300

ugcggcuccc gcuguagcuc cgaccaagug gaaacccagg caugcacgag ggagcagaau      360

cggaucugca cuugucgccc cgggugguac ugcgccuuga guaaacagga gggcuguagg      420

cugugcgcgc cacuccggaa gugucgcccg gguuucgggg ucgccaggcc cggcaccgaa      480

acuagcgaug ugguaugcaa accaugugca cccggcaccu uuuccaacac cacgagcagu      540

acugacauuu gccggccaca ccaaaucugu aauguggucg ccauucccgg gaacgcaucc      600

auggaugccg ugugcaccag cacuuccccg acccgcagua uggcccccgg ugcggugcau      660

cugccacagc ccgucagcac caggucccag cacacucagc caacgcccga gccaagcacc      720

gcaccgagua cuuccuuccu gcuccccaug ggcccaaguc ccccagccga agggagcacc      780

ggcgacuuug cccugcccgu ggguuugauc guagggguga ccgcacuggg ccuccugauu      840

aucggcgucg ugaauugcgu gaucaugacu caagucaaga agaaaccgcu guguuugcag      900

cgggaggcca aggugccaca ucuccccgcg gauaaagccc gcgggacgca gggucccgag      960

caacagcauc ugcugauuac cgcaccaucc agcagcucca guagccucga auccagcgcc     1020

agugcacugg acaggcgggc ccccacucgc aaccagccac aggccccggg cguagaggca     1080

uccggggccg gcgaagcgag ggccagcacc gguuccagug auagcucccc cggcgggcac     1140

ggcacccaag ugaaugucac uugcaucgug aacgucugua gcaguuccga ccacagcucc     1200

cagugcagua gccaggcauc cagcacgaug ggggauaccg acaguucccc aagcgagucc     1260

cccaaggacg aacaggugcc auucagcaaa gaggagugug ccuuucggag ucaauuggaa     1320

acucccgaga cccugcucgg uagcacugaa gagaagccgc ugccacuggg cgugcccgau     1380

gccgggauga aaccauccug aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  2120
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt7)

<400>  2120
gggagaaagc uuaccaugcc cgugaugagg cuguucccau gcuuucucca gcuguuggcc       60

ggccuggcac ucccggccgu gcccccacaa cagugggcgc ugagcgccgg gaacgguucc      120

agugaggucg aaguagugcc cuuccaggag gucuggggcc ggagcuacug ucgcgcauug      180

gaaaggcugg uggacguggu cuccgaguau ccaagugaag uggagcacau guuuagcccc      240

uccugcguaa gccuccugcg guguaccggg ugcuguggcg augagaaucu gcauugcgug      300

ccagucgaaa cugccaacgu gaccaugcag cuccugaaga uccgcuccgg ugacaggccg      360

aguuacgugg aguugacguu cagccaacac guccggugug aaugccgccc ccugagggag      420

aaaaugaagc cagagcggcg caggcccaaa gggcggggca agcgcaggcg ggaaaaacag      480

cgcccaacug auugucaucu cugcggcgac gcagugccca ggcggugagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  2121
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt7)

<400>  2121
gggagaaagc uuaccaugac cgacaggcag acugauaccg cccccagccc auccuaccau       60

cugcucccgg gccggcgcag gacgguggac gcagccgcga gucgggggca aggucccgag      120

ccagcccccg gcgggggcgu cgaaggugug ggggcacgcg gcguagcccu gaaguuguuc      180

gugcagcugc ucggcugcag cagguuuggg ggugcagucg ugcgggccgg cgaggcggaa      240

ccauccgggg ccgcacgcag ugccagcucc ggcagggagg aaccccagcc agaggagggu      300

gaagaggaag aggagaaaga agaggaacgg gggccgcagu ggcgccuggg cgccaggaag      360

cccggcagcu ggacugggga ggcagccgug ugugcggauu ccgccccagc agcccgggca      420

ccccaagccu uggcccgcgc gagugguagg ggcgggcggg ucgcacgcag gggcgccgaa      480

gagagcgguc caccccacuc cccgagccgg cgcggcagug ccuccagggc agggcccggc      540

cgggccagcg agaccaugaa cuuccugcuc uccugggugc acuggagucu ggcgcugcuc      600

cuguauuugc aucacgccaa auggagccag gcagccccaa uggcagaagg ggguggccag      660

aaucaucacg agguagugaa guuuauggac gucuaccaga gguccuauug ccaccccauc      720

gaaacccugg uggauauuuu ccaagaguac ccagacgaaa ucgaguauau uuuuaaaccc      780

agcugugugc cacucaugcg cugcgggggc uguugcaacg augagggucu ggaauguguc      840

ccgacugagg aaaguaauau caccaugcag auuaugcgga ucaagcccca ucagggccag      900

cacaucgggg agauguccuu ccugcaacau aacaagugcg aauguaggcc caaaaaggac      960

cgcgcccggc aggagaaaaa gagcgugagg ggcaaaggga agggccagaa acgcaagcgg     1020

aagaaaagua gguacaaguc cuggagcgua uaugugggug cccggugcug cuugaugcca     1080

uggagccucc cagggcccca cccguguggc ccaugcuccg agcgcaggaa acaccuguuu     1140

guccaagauc cccagacgug uaagugcagu uguaaaaaua cugacagccg gugcaaggca     1200

cgccagcugg aacucaacga gaggaccugu cggugcgaua agcccaggcg cugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2122
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt7)

<400>  2122
gggagaaagc uuaccaugaa cuuccugcuc agcugggugc acuggucccu ggccuugcug       60

cucuaccugc aucacgcaaa guggagucag gccgcgccca uggccgaggg cgggggucaa      120

aaucaucacg aagucgugaa auuuauggac guauaucaga ggagcuacug ccauccaauc      180

gagaccuugg uggauauuuu ccaggaauau ccggacgaga ucgaauacau uuuuaagccc      240

uccugugucc cacugaugcg gugcggcggg uguugcaacg augagggccu cgagugugug      300

cccacugaag agaguaauau caccaugcag auuaugcgca ucaaaccaca ccaaggucag      360

cacaucgggg aaaugagcuu ccugcagcau aacaagugcg aguguaggcc caaaaaggac      420

cgggcacgcc aggagaagaa auccgugagg ggcaagggca aagggcaaaa gcggaaacgc      480

aagaaaagca gguauaaguc cuggaguguc uacgugggug cccggugcug ucugaugcca      540

uggagccucc cgggccccca cccaugcggg cccugcuccg aacgcaggaa gcaucuguuu      600

guacaggauc cacagacgug uaaaugcagc uguaagaaua cugacagucg gugcaaagca      660

cgccaguugg agcugaacga aaggaccugu cggugcgaua agcccaggcg cugaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  2123
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt7)

<400>  2123
gggagaaagc uuaccaugag cccccugcuc aggcggcugu ugcuggccgc acuccugcag       60

uuggccccag cgcaagcccc ggugucccag cccgacgcac caggccacca gcgcaagguc      120

gugaguugga ucgauguaua caccagggcc acuugccagc cccgggaggu ggucgugcca      180

cugaccgugg aacucauggg gacggucgca aaacaacugg ugcccagcug uguaacugug      240

cagcgcugcg guggcuguug cccagacgau gggcuggagu gugucccgac cggccagcau      300

caggugagga ugcaaauucu caugauccgg uaucccucca gucagcuggg ugaaaugagc      360

uuggaggaac acucccagug cgagugucgc ccaaagaaaa aggacagcgc cgugaaaccc      420

gauagggcgg ccaccccaca ucaccggccc cagccgcgcu ccguccccgg gugggacagu      480

gcaccaggcg cccccagccc agccgauauu acucauccca ccccagcacc gggccccucc      540

gcccacgcgg ccccaagcac gaccagugca cugacucccg ggccagccgc agccgccgcg      600

gacgcagccg ccuccagcgu ggcaaagggu ggcgccugag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  2124
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt7)

<400>  2124
gggagaaagc uuaccaugca ucugcucggc uucuuuagcg uggccugcuc ccuguuggca       60

gccgcgcugc uccccgggcc aagggaggcc ccggcagccg cagccgcguu cgaaaguggu      120

cuggacuuga gcgaugccga gcccgacgca ggcgaagcca ccgccuacgc auccaaggau      180

cuggaggaac agcuccggag ugucagcucc guggacgagc ugaugacugu acuguaucca      240

gaguacugga aaauguauaa gugucaacuc cgcaaagggg gcuggcagca caacagggaa      300

caggccaauc ugaacagccg gaccgaggaa acgaucaagu uugcggccgc acacuacaau      360

acugagauuu ugaaauccau cgauaacgag uggcgcaaga cccagugcau gcccagggaa      420

guguguauug acgucgguaa ggaguucggg guggccacca auacuuucuu caaaccaccc      480

ugcgugagug ucuaucggug uggcggcugc uguaacagcg aagggcugca augcaugaau      540

accuccacga gcuaccucag uaagacucug uuugagauca ccgugccacu gucccagggu      600

ccgaaacccg uaacuauuag cuucgcaaac cauaccuccu gucgcugcau gaguaaguug      660

gauguguaua ggcaggucca cagcaucauc cggcgcuccc ucccagccac ccugccccag      720

ugccaagccg cgaauaaaac guguccaacu aacuacaugu ggaauaacca uauuuguagg      780

ugccuggcac aggaagacuu uauguucagc agugaugccg gcgacgauuc caccgacggg      840

uuucacgaua ucugcggccc caauaaggag cucgacgagg aaacuuguca gugcgugugu      900

cgggccgguc ugcgcccggc aagcugcggg ccccacaaag aguuggacag gaacaguugu      960

cagugcgugu gcaagaauaa gcuguuccca ucccaaugug gcgccaaccg ggaauuugau     1020

gagaauaccu gccagugugu cugcaaacgc accuguccca ggaaccagcc acucaacccc     1080

ggcaagugcg cgugugaaug cacugagagc ccacaaaaau gucugcugaa ggggaaaaag     1140

uuucaucacc agacgugcag cuguuaccgg cgcccgugca ccaauaggca gaaggccugc     1200

gagcccgguu ucuccuauag ugaagaggug ugucggugcg uaccaagcua cuggaaaagg     1260

ccccagaugu ccugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  2125
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt7)

<400>  2125
gggagaaagc uuaccaugua cagggagugg guggucguga acguauucau gaugcuguau       60

gugcagcucg uccaaggcag cuccaaugaa cacgggcccg ugaagcggag uagccagucc      120

acccuggagc gcagugaaca gcagaucagg gccgcaagcu ccuuggagga acugcuccgg      180

auuacucaua gcgaggacug gaaacugugg cgcugcaggu ugcggcugaa guccuuuacc      240

aguauggaua gccgcuccgc cagccacagg aguacgcggu ucgcggccac uuuuuacgac      300

aucgagaccc ucaaagugau ugaugaagag uggcaacgca cccaguguuc cccaagggaa      360

acuugcgucg agguggcaag cgagcugggu aaguccacca acacguucuu uaaaccgccc      420

uguguaaaug uguuccggug cggcgggugu ugcaacgaag agagucugau cuguaugaau      480

acuagcaccu ccuauauuag caagcagcuc uuugaaauca gugucccacu gacuuccgug      540

cccgaguugg ugccagucaa gguggccaac cauaccggcu gcaaaugucu gcccaccgca      600

ccacgccacc cguacagcau cauuaggcgg aguauccaga uucccgaaga ggaccgcugc      660

ucccauagca agaaacucug cccaaucgau augcuguggg acagcaauaa guguaaaugc      720

guacugcaag aggaaaaccc cuuggccggu acggaggauc acucccaccu ccaggaacca      780

gcgcugugug ggccccauau gauguucgac gaggauaggu gcgaaugugu gugcaagacu      840

ccguguccca aagaccugau ucagcaccca aagaauugca guuguuuuga gugcaaggag      900

agccucgaaa ccugcuguca gaaacauaag cuguuccacc ccgauacuug cuccugugag      960

gaccggugcc cauuucacac ccgccccugu gccagcggca aaaccgcaug cgccaagcau     1020

uguagguucc caaaagaaaa gcgggccgca caaggcccgc acaguaggaa gaaccccuga     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  2126
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt8)

<400>  2126
gggagaaagc uuaccaugga cuccgacgaa accggcuucg aacacuccgg ccucuggguc       60

uccguccucg ccggccuacu acuaggcgcc ugccaagccc accccauccc cgacucaucc      120

ccacuucuac aauucggcgg acaagucaga caacgauacc ucuacaccga cgacgcccaa      180

caaacagaag cccaucucga aauaagagaa gacggcaccg ucggcggcgc cgccgaccaa      240

ucccccgaau cccuacucca acucaaagca cucaaacccg gcgucaucca aauccucggc      300

gucaaaaccu cccgcuuccu augccaacgc cccgacggcg ccuuauacgg cucccuacac      360

uucgaccccg aagccugcuc uuuucgcgaa cuccuacucg aagacggcua caacguauac      420

caauccgaag cccacggccu accccuacac cuccccggca acaaaucacc ccaccgcgac      480

ccagccccac guggccccgc acgcuuccuc ccacuaccag gccucccacc cgcccucccc      540

gaaccacccg gcauccucgc accccaacca cccgacguag gcuccucaga cccccucucc      600

auggucggcc ccucccaagg ccgcucaccc ucauacgccu cauaaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  2127
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt8)

<400>  2127
gggagaaagc uuaccaugca cuccuuccca ccccuccucc uacuucucuu cuggggcgua       60

guaucccacu ccuuccccgc cacacuagaa acccaagaac aagacguaga ccugguccaa      120

aaauaccuag aaaaauacua caaccucaag aacgauggac gacaagucga aaaacgccgc      180

aacuccggcc cggucguaga aaagcuaaaa caaaugcaag aguucuucgg ccuaaaaguc      240

acuggcaaac cagacgccga aacccucaaa gucaugaaac aaccacgaug cggcguccca      300

gacgucgcac aauucguccu cacagaaggc aacccccgau gggaacaaac ccaccucacc      360

uaccgaauug aaaacuacac accugaccug cccagagccg acguagacca cgccauagaa      420

aaagccuuuc aacucugguc aaacgucaca ccccucaccu uuaccaaagu cucggaaggc      480

caagccgaca uaaugauuag cuucguucga ggcgaccaca gagacaacuc ccccuucgac      540

ggacccggcg gcaaccucgc ccacgccuuc caacccggcc cggguauagg cggagaugca      600

cauuucgacg aagacgaacg cuggacaaac aacuucagag aauacaaccu ccaccgugua      660

gcagcccacg aacuaggcca cucacucgga cucucacaca gcaccgacau cggagcccua      720

auguacccau ccuacacuuu cuccggagac guucaacucg cccaagacga caucgacggc      780

auccaagcaa ucuacggccg cucccaaaac ccaguacaac ccaucggacc acagacuccc      840

aaagccugcg acuccaaacu caccuuugac gcaaucacca ccauccgagg cgaagucaug      900

uucuucaaag accgcuucua caugcgcacg aaccccuucu acccagaagu cgaacucaac      960

uucauaucag ucuucuggcc ccaacuacca aacggccuug aagcagcaua cgaauuugcc     1020

gacagagacg aaguccgcuu cuucaaagga aacaaauacu gggccgucca aggccaaaac     1080

guccuucacg gcuaccccaa ggacauauac uccuccuucg gcuucccccg aacagucaaa     1140

cacaucgacg cggcacuguc cgaagaaaau accggcaaga cauacuucuu cgucgccaac     1200

aaauacuggc gguacgacga auacaaacga uccauggacc ccggcuaccc caaaaugaua     1260

gcacacgacu ucccgggaau cggccacaaa gucgaugcag uauucaugaa agacggauuc     1320

uucuacuucu uccacggcac acgccaauac aaauucgacc ccaaaacaaa acgcauccuc     1380

acccuccaga aagccaacag cugguucaau ugccgcaaaa acuaaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  2128
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt8)

<400>  2128
gggagaaagc uuaccaugca cuccuucccu ccccuacuac uccuacuauu cuggggaguc       60

guaucacacu ccuucguccu caccgaaggc aacccucgau gggaacaaac ccaccucacu      120

uaccgaaucg agaacuacac ccccgaccuc ccacgagccg acgucgacca cgccaucgaa      180

aaagccuuuc aacuaugguc caacgucaca ccccucaccu ucacuaaagu aagcgaaggc      240

caagccgaca ucaugaucag cuucguccgc ggagaccacc gagacaauuc ccccuucgac      300

ggcccaggag gcaaccuagc ccacgccuuu caaccaggac ccggcauagg aggcgacgcc      360

cacuucgacg aagacgaacg auggacaaac aacuuccgcg aauacaaccu ccacagagua      420

gccgcccacg aauuaggcca cucccuagga cucucacacu caaccgacau aggugcccuc      480

auguaccccu ccuacaccuu cagcggcgac guccaacuag cccaagacga caucgacggc      540

auacaggcca ucuacggccg aucucaaaau ccaguccaac ccauaggacc acagacacca      600

aaagccugug acuccaaacu caccuucgac gccaucacca ccauacgcgg agaagucaug      660

uucuuuaaag acagauucua caugcguacc aaccccuucu acccagaagu agaacuaaac      720

uucauaucug ucuucuggcc acaacucccc aacggccuag aagcagcaua cgaauuugcu      780

gacagagacg aaguacgauu cuucaaaggc aacaaauacu gggccgucca aggccaaaac      840

guacuacacg gcuacccaaa agacaucuac uccuccuucg gcuucccccg cacagucaaa      900

cacaucgaug ccgcacucag cgaagaaaac accggaaaaa ccuacuucuu cgucgccaac      960

aaauacuggc gauacgauga auacaaacga uccauggacc ccggauaccc caaaaugauc     1020

gcccacgacu uccccggaau aggccacaaa gucgacgcag uuuucaugaa agacggcuuc     1080

uucuacuucu uccacggaac cagacaauac aaauucgacc ccaaaaccaa acgcauccuc     1140

acccuccaaa aagccaacuc cugguucaac ugccgcaaaa acuaaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  2129
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt8)

<400>  2129
gggagaaagc uuaccaugaa gaaaaacauc cucaaaauac ucauggacuc guauucuaag       60

gaauccaaaa uccaaaccgu cagacgcguc acuagcgucu cccuccucgc gguguaccua      120

acuaugaaua cguccagccu aguccucgca aagccuaucg agaacaccaa cgacaccagc      180

auuaaaaacg uugagaagcu acgcaacgcg ccaaacgagg aaaacucaaa gaaagucgaa      240

gacagcaaaa augacaaagu agagcacguu aaaaacauag aagaagccaa gguggaacaa      300

guagcaccgg aagucaaaag caaaaguacc cuacgcagcg ccagcauugc caacaccaac      360

agcgaaaagu acgacuucga guaucuuaac gggcucagcu acacagaacu aacaaaccug      420

aucaaaaaca uaaaauggaa ccaaauaaac gguuuguuca acuacagcac agggucacaa      480

aaauucuucg gcgauaaaaa ccgcguccag gccaucauaa acgcccuaca agaaagcggc      540

cgcacauaca ccgcgaacga caugaaggga auagaaaccu ucacggaggu auuaagggcg      600

ggguucuacc uaggcuacua caaugacgga cucucauacc uaaacgaccg caacuuccaa      660

gacaagugca uccccgccau gauagccaua cagaaaaacc caaauuuuaa acucggcacg      720

gccguccaag acgaaguuau aacauccuua gggaaacuca ucggaaacgc cucggccaac      780

gccgaagugg ugaacaacug cguccccgua cuuaagcaau uccgcgaaaa ccuaaaccaa      840

uacgcacccg acuacguuaa ggggaccgcg gucaacgaau ugauaaaagg aaucgaguuc      900

gacuuuagcg gagcagcaua ugaaaaggac gugaagacaa ugcccuggua cggcaagauu      960

gauccguuca uuaacgaacu caaggcccuc ggacuauacg gaaacauaac cucagcaacc     1020

gagugggcuu cagauguagg caucuacuac cugagcaagu ucggccuaua cagcaccaac     1080

cgcaacgaca uugugcaaag uuuagaaaaa gcagucgaca uguacaagua cggcaagauu     1140

gcauuuguag cgauggaacg aauaacgugg gacuacgacg gcaucggcuc caacggaaag     1200

aaagucgacc acgacaaguu ccuggaugac gccgagaagc acuaccuccc caagacauac     1260

accuucgaca acggcaccuu caucauccga gccggcgaca aaguaucgga agaaaagauc     1320

aagagacuau acugggccuc cagagaaguc aaaucccaau uccaccgagu cgucggaaac     1380

gacaaggccc uagaaguagg aaacgccgac gacguauuaa cuaugaaaau uuuuaacagc     1440

ccagaagaau acaaauucaa caccaauauu aacggcguau caacagacaa cggaggacug     1500

uacauagaac cccgagggac auucuacaca uacgaacgga ccccacaaca auccaucuuu     1560

agccuggaag aacucuucag acacgaauac acccacuacc uacaggccag auaccuaguc     1620

gacgguuuau ggggacaagg ccccuucuac gagaaaaacc gacucacaug guuugacgag     1680

ggcacagccg aguucuucgc aggaucaaca agaaccagcg gcgugcuccc gcgaaagucg     1740

auccuuggcu auuuagcgaa agacaaagua gaccacagau acagccuaaa gaaaacacug     1800

aacucaggcu acgacgauag cgacuggaug uucuacaacu auggcuucgc aguagcgcac     1860

uaccuuuacg aaaaagacau gccgacguuc aucaagauga acaaagcaau acuaaacacc     1920

gacguuaaau cguacgacga aauaaucaaa aagcuguccg acgaugccaa caaaaacaca     1980

gaauaccaaa accauaucca ggaacucgcg gacaaguacc agggggcagg aaucccccua     2040

gucucggacg acuaccuaaa agaccacggc uacaagaaag caagcgaagu auacagugag     2100

aucagcaaag ccgccucccu aacgaacaca ucagugacug cugagaaaag ccaguacuuc     2160

aacaccuuca cacuccgagg aacuuacacg ggagaaacau caaaaggcga guucaaagac     2220

ugggacgaaa ugagcaagaa auuagacggc acccuagaau cacuagcgaa aaacucuugg     2280

agcggauaca agacccuuac cgcauacuuc acgaacuaca gggucaccag ugacaacaaa     2340

gugcaguacg acgucguguu ccacggaguu cuaacagaca acgccgacau cuccaauaac     2400

aaagcaccaa ucgccaaggu gacggggcca agcacaggag ccgucggacg aaacauagag     2460

uucucaggca aagacagcaa ggacgaagac gggaagauag uaaguuacga cugggacuuc     2520

ggugacggag caacaucccg cgguaagaac agugugcacg cauauaagaa ggccggaaca     2580

uacaacguaa cccuaaaggu aacggacgac aaaggagcga cagcgaccga aucguuuacu     2640

aucgaaauaa agaacgaaga cacgaccacu ccaauaacaa aagaaaugga accaaacgau     2700

gacaucaaag aagccaacgg cccuauaguc gaagguguaa ccguaaaagg cgaccucaac     2760

ggcuccgacg acgcagacac guucuacuuc gacgugaaag aagacgggga cguaacaauc     2820

gaacuccccu acuccggcuc cucaaacuuc accuggcuag uauacaagga aggggacgau     2880

caaaaccaca ucgcaagcgg aaucgauaaa aacaauagua aaguagggac cuucaaaucg     2940

acaaagggaa ggcacuacgu cuucauuuac aagcacgaca gcgccagcaa cauaaguuac     3000

uccuuaaaca ucaaaggacu aggcaacgaa aaacuuaagg aaaaagagaa caacgacuca     3060

agcgacaaag cgacuguaau cccaaacuuc aauacgacaa ugcaagguuc ccuccucgga     3120

gacgacucac gggacuacua cagcuucgaa gucaaggaag aaggcgaagu gaacaucgaa     3180

cuggacaaaa aggacgaguu cggcguaacc uggacccugc accccgaaag caacaucaac     3240

gacaggauca ccuacggcca aguagacggc aacaaaguca gcaacaaagu caaacuccgc     3300

cccggcaagu acuaccuacu ggucuacaag uacagcggcu caggaaacua cgaacuccgc     3360

gucaacaagu aaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  2130
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt8)

<400>  2130
gggagaaagc uuaccaugaa augggucacc uucauaagcc uccucuuucu guucagcagc       60

gcauacucaa uagccaacac caacucagaa aaauacgacu ucgaauaccu aaacggccua      120

agcuacaccg aacuaaccaa ccucaucaaa aacauaaaau ggaaccaaau aaacggccua      180

uucaacuaca gcaccggcag ucaaaaguuc uucggugaca agaaccgcgu ccaggcgaua      240

aucaacgccc uacaagaauc cggccgcacc uacacagcca acgacaugaa aggcauagaa      300

acauucacgg aaguacuacg ugcuggauuc uaucuaggcu auuauaacga cggacugagc      360

uaccuaaacg acaggaacuu ucaagacaaa ugcauccccg ccaugauagc aauccagaaa      420

aaucccaacu uuaaacucgg aacggcgguc caagacgagg ugaucacguc acuuggaaaa      480

cucauaggaa acgcgagcgc caacgccgag guaguaaaua acugcguacc aguccugaag      540

caauuccgug aaaaucuuaa ccaauacgcc ccagacuacg uaaaaggaac ugcggucaac      600

gagcucauaa aaggaauaga guucgacuuc agcggagccg cauaugaaaa agacguaaag      660

accaugcccu gguacggcaa aauagacccg uucaucaacg aacucaaggc acuaggccua      720

uacggcaaca ucacaagcgc caccgaaugg gccucagacg ucgggaucua cuaccuauca      780

aaauucggac ucuacagcac aaaccgaaac gacaucguac aaucccuaga aaaagcaguc      840

gacauguaca aauacggaaa gaucgcauuc gucgccaugg agcgcaucac gugggauuac      900

gacggaauag gcucaaacgg aaagaaaguc gaccacgaca aauuccucga cgacgcagaa      960

aaacacuacc ugccgaaaac uuauacguuu gacaacggca ccuucauuau ccgcgcgggc     1020

gacaaaguau cugaggaaaa gaucaaacga cuauacuggg cuagccgaga aguaaaaagc     1080

caguuccacc gaguagucgg aaacgauaag gcgcucgaag uaggaaacgc cgacgacguc     1140

cuuacuauga agaucuucaa cagccccgaa gaauacaaau ucaacacuaa caucaacggc     1200

guauccacag acaacggagg ccuauacauc gaaccuaggg gcaccuucua caccuacgaa     1260

cgcaccccac aacaaucaau cuucucucuu gaagaacucu uccggcacga guacacccac     1320

uaccuacaag cacgauaccu cgucgacggc cuauggggcc aaggaccauu cuacgagaaa     1380

aacagacuca ccugguuuga cgaagggacc gcugaguucu ucgccggcag cacaagaaca     1440

ucaggagucc ucccccgaaa gagcauccua ggauaccugg ccaaggacaa gguagaucac     1500

cgcuacagcc uaaagaagac acuaaacagc ggcuacgacg acuccgacug gauguucuau     1560

aauuacggcu ucgcgguagc acacuaccug uaugaaaaag acaugccaac cuucaucaaa     1620

augaacaaag caauacuaaa caccgauguc aaaagcuacg augaaauuau caaaaagcug     1680

agcgacgacg caaauaaaaa caccgaauau caaaaccaca uccaggaacu cgccgacaaa     1740

uaccaaggcg cagggauccc ccugguguca gacgacuacc uaaaagacca cggcuacaag     1800

aaagccucgg aagucuacuc cgaaaucagu aaagcagcca gccuaaccaa uacaucaguu     1860

acagccgaaa agagccagua cuucaacaca uucacacuga ggggcaccua cacaggcgaa     1920

acuuccaaag gggaguucaa ggacugggac gaaaugagca agaagcucga cggcacccuc     1980

gaaucacucg cuaaaaauuc auggucggga uacaagacuu uaacggcaua cuucacgaac     2040

uaccgaguga caagcgacaa caaaguccaa uacgacgucg ucuuucacgg cguccugacc     2100

gacaacgcag acauauccaa caacaaagca ccgaucgcaa aagucaccgg accgagcacc     2160

ggggcagucg ggagaaacau cgaguucuca ggcaaagacu ccaaggacga ggacggcaaa     2220

aucgucagcu acgacuggga cuucggagac ggcgcaacaa gccggggcaa gaacucaguc     2280

cacgccuaca agaaagcagg aaccuacaac guaacacuaa aaguaaccga cgacaaaggg     2340

gcaacagcca ccgaaucguu caccauagaa aucaaaaacg aagacaccac cacccccauu     2400

acgaaagaga uggaaccgaa ugacgacauc aaagaggcua acggcccuau cgucgagggc     2460

guaaccguaa aaggcgaccu uaacggaucg gaugacgcag acaccuucua cuucgacgua     2520

aaagaagaug gcgacgucac uaucgagcuc ccauacuccg gcuccagcaa cuucaccugg     2580

cucguauaca aggaagguga cgaccagaac cacaucgcuu cggggauaga caaaaauaac     2640

ucuaaaguug gcacauucaa gagcacaaaa ggccggcauu acguuuucau auacaagcac     2700

gacuccgcuu caaacaucag uuacagccuc aacaucaagg gacugggaaa ugagaagcuc     2760

aaagagaaag agaacaacga cuccuccgac aaagccacgg uaauacccaa cuucaauacg     2820

accaugcaag guucucuacu cggcgacgac agcagggacu acuacucguu ugaggucaag     2880

gaggaaggcg aaguaaacau agagcuugac aagaaagacg aguucggugu gacguggaca     2940

cuacacccag aguccaacau aaaugacaga auaacauacg gccagguaga cggcaacaag     3000

gugagcaaca aagucaaacu ccgacccggu aaauacuacc uauuagucua caaauacucc     3060

ggaagcggga acuacgagcu acgcgucaau aagugaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  2131
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt8)

<400>  2131
gggagaaagc uuaccaugaa auggguaacc uucauauccc uccuguuccu auucucauca       60

gcauacagca ugaagaaaaa cauccucaaa auccuaaugg auagcuacuc aaaggaaagu      120

aaaauccaga cgguucgccg agugacgucc gucucccuuc uagcaguaua ccucacuaug      180

aacacaagcu cccuaguccu ggccaaaccc auugaaaaca ccaacgacac cucuauaaag      240

aacguagaaa aacuccgaaa cgccccaaac gaggaaaacu caaagaaagu agaggauucu      300

aaaaacgaca aaguagaaca cgucaaaaac auagaagagg ccaaaguaga acaagucgcc      360

ccggaaguca aauccaaaag cacgcugcgg ucggcgucuc gccggcgacg gaaacgcaua      420

gcaaacacaa acucggaaaa auacgacuuc gaauaccuca acggacucag cuacaccgaa      480

cugacgaacc ucaucaaaaa caucaaaugg aaccaaauca acggacuguu caacuacucc      540

acaggauccc aaaaguucuu cggcgacaaa aaccgaguac aggcgaucau aaaugcccug      600

caggaaagcg gcagaacuua uaccgcaaau gacaugaagg gcaucgaaac guucaccgag      660

guccugagag cgggcuucua ccuaggauac uacaacgacg gacucagcua ccucaacgac      720

cgcaacuuuc aggauaaaug cauaccggca augaucgcaa uccagaaaaa ccccaacuuc      780

aaacuuggaa cagcgguaca agaugagguc aucacaucgc ugggaaagcu aauaggaaac      840

gccuccgcaa acgccgaagu agucaacaac ugcgucccug uauuaaaaca auuccgugag      900

aaccucaacc aauacgcccc cgacuacguc aaaggcaccg ccgucaacga acugauaaag      960

ggcauagagu ucgacuucag uggagcagca uacgaaaaag acgucaagac caugcccugg     1020

uacggcaaaa ucgaucccuu caucaaugaa cucaaagcgc uuggccucua cggaaacaua     1080

accucugcca cagaaugggc aagcgacguc ggaauauauu accuauccaa auucggccuc     1140

uacagcacaa acagaaacga cauaguacag ucacucgaaa aagcugucga cauguacaaa     1200

uacggaaaga uagcauucgu cgcaauggaa cgcauaacau gggacuacga cggcauaggg     1260

uccaacggca agaaaguaga ccaugacaag uuccuagacg acgcagaaaa acacuaccug     1320

cccaagaccu acaccuucga caacggaacc uucauaaucc gagcaggcga caaaguaagc     1380

gaagagaaaa uaaaacgccu auacugggcc agucgagaag ucaaaucaca auuccaccga     1440

gucguaggca acgacaaggc acuagaagug ggaaacgccg acgauguccu aacuaugaaa     1500

aucuucaaca gcccggaaga auacaaauuc aacaccaaca ucaacggggu cucaaccgac     1560

aacggcgggc uguacauaga gccgcgcggc acguucuaca cguacgagcg cacaccccaa     1620

caaagcaucu uuucgcuaga agaacuuuuc cgacacgaau auacccacua cuuacaggcu     1680

cgauaccucg uagauggccu auggggccaa ggcccauucu acgaaaagaa cagacucacc     1740

ugguucgacg aaggaaccgc agaguucuuc gcaggaucga ccaggacgag cggcguccuc     1800

ccaaggaaau ccauacuugg auaccucgca aaagauaagg uagaccaccg guacucacuu     1860

aaaaagacuc ucaacucagg auacgacgac uccgacugga uguucuacaa cuacggcuuu     1920

gccguggcuc acuaucugua cgaaaaggac augcccaccu ucaucaagau gaacaaagcc     1980

auccucaaca ccgacguaaa aagcuacgac gaaauaauca agaaacucuc agacgacgcg     2040

aauaaaaaca cagaauacca aaaucacaua caagagcucg ccgacaaaua ccagggcgcg     2100

gggauaccgc ucgucucuga cgacuaccuc aaagaccacg gguacaagaa agccagcgag     2160

gucuacagug aaaucagcaa agccgccucg cuaaccaaca ccagcguaac ggcggagaaa     2220

agccaguacu ucaacaccuu cacacuaaga ggaaccuaua ccggugagac cagcaaaggc     2280

gaguucaagg acugggacga aauguccaag aaauuagacg ggacccuaga aucgcuggcc     2340

aaaaacuccu ggagugggua uaagacccuu accgcguacu ucacaaacua cagagugacc     2400

agcgacaaua aaguccagua cgaugucgug uuccacggcg ugcuaacaga caaugcagac     2460

aucucaaaca acaaagcccc aaucgccaaa gucacgggac ccagcacagg cgccguaggc     2520

cgcaacaucg aauuuucagg uaaggauuca aaagacgaag acggcaagau cgucagcuac     2580

gacugggacu ucggagacgg cgccaccagc agagggaaaa acucaguaca cgcguacaag     2640

aaggccggga ccuacaacgu cacccuaaaa guuacggaug acaaaggcgc cacagccacg     2700

gaauccuuca ccauagaaau caagaacgag gacacaacua cccccauaac caaagagaug     2760

gagccaaacg augacauaaa agaagcuaac ggcccaaucg uggaaggcgu uacugucaaa     2820

ggggaccuaa acggcucaga cgacgccgac accuucuacu uugacguaaa agaagacggg     2880

gacgucacaa uagaacuccc auacuccgga aguagcaacu ucaccuggcu aguguacaag     2940

gaaggggaug aucaaaacca cauagcaucc ggcauagaca agaacaacuc aaaaguuggg     3000

accuucaaau cgaccaaagg ccggcacuac guauucaucu acaaacacga cuccgcaagu     3060

aauauaucau acagccuaaa cauaaagggg cugggaaaug aaaaacuuaa ggaaaaagaa     3120

aacaacgaca guagcgacaa agcaacagug auccccaacu ucaauacaac caugcaaggc     3180

ucacuccucg gagaugacuc aagggacuac uacucauucg aagugaagga agaaggcgaa     3240

gucaacaucg aacucgacaa gaaggacgag uucggcguca ccuggacccu ccacccugaa     3300

ucaaacauaa acgacaggau caccuacggc caaguagacg gaaacaaagu gucaaacaag     3360

guaaaacuca gaccggggaa auauuaccua cugguguaca aauauucugg aagcggaaac     3420

uacgaacuac gagucaacaa auagggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  2132
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt8)

<400>  2132
gggagaaagc uuaccaugaa cuuccucaaa auaauccuaa accgaggcaa aaccaugaag       60

cgcaaaugcc ucagcaagag acucaugcuc gcaaucacca uggcuacaau cuucacaguu      120

aacucaacuc uccccaucua cgccgcggua gacaaaaaca acgcaaccgc cgccguccaa      180

aaugaaucua aacgauacac agucagcuac cuaaaaaccc uuaacuacua cgaccucgua      240

gaccugcucg ugaaaaccga aaucgagaac cucccggacc uguuccaaua uuccagcgau      300

gccaaagagu ucuacgggaa caaaacacga augucguuca ucauggacga aaucggacgc      360

cgagcgcccc aauacaccga gauugaucau aagggaaucc cgacgcucgu cgaagucguc      420

cgagccgggu ucuaucucgg cuuccacaac aaggaacuca acgagauaaa caaacgcucu      480

uucaaggaac gcgucauacc guccauacuu gccauacaga aaaaccccaa uuucaagcuc      540

ggaacagaag uacaagacaa aaucguaucc gccaccggcc ugcuagccgg aaacgaaacc      600

gcaccaccag aagucgucaa caacuucacu cccauccuuc aagacugcau caagaacauc      660

gacagauaug cauuggacga ccuaaaauca aaagcacugu ucaacguucu agccgcgccc      720

acauaugaua uaaccgaaua ccucagagca acaaaggaga aacccgaaaa cacucccugg      780

uacggcaaaa ucgacggcuu caucaacgaa cuaaagaaac ucgcauuaua cggcaaaauc      840

aacgacaaca acaguuggau cauagacaac ggcauauacc acaucgcgcc acuaggaaaa      900

cuacacucua acaacaaaau cggaaucgaa acacuaaccg aagucaugaa gguauacccc      960

uaccugagca ugcaacaccu ucaaucugca gaucaaauca aacgacacua cgacagcaaa     1020

gacgccgagg gaaacaagau cccauuagac aaauucaaga aagaaggaaa agagaaauac     1080

ugcccaaaga ccuacacguu ugaugauggc aaaguaauca uaaaggccgg cgcacgcguc     1140

gaggaagaaa aagucaaacg ccuguacugg gcgucaaaag aagucaacuc ccaauucuuc     1200

cgagucuaug gcaucgacaa accccucgag gaaggcaacc ccgacgacau acugacaaug     1260

gucauuuaca acucgccuga ggaauacaaa cugaacucag ugcuauacgg cuacgacacc     1320

aacaacggcg gcauguacau cgaacccgaa ggcacuuucu ucacuuacga gagagaggcc     1380

caagaaucca cguacacacu agaagaacuu uuccgacacg aguacaccca cuaccuccaa     1440

ggccguuacg cagucccggg acaaugggga cgaacgaaac ucuacgacaa cgacaggcug     1500

accugguacg aagagggcgg ggcggaacua uucgcaggga gcaccaggac aucggggaua     1560

cuucccagga aauccaucgu cuccaacauc cacaacacaa cacgaaauaa ucgguauaaa     1620

cugagcgaua ccguccacuc aaaauacggc gcgucauucg aguucuacaa cuacgccugu     1680

auguucaugg acuacaugua caacaaagau augggaaucc ucaacaaauu aaacgaccuc     1740

gcuaagaaca acgacguaga cggcuacgac aacuacauaa gagaccuauc cucaaacuac     1800

gcucugaacg acaaauacca agaccacaug caggaacgaa ucgacaacua cgaaaaccuc     1860

accgucccgu ucgucgccga cgacuaccuc gugagacacg ccuacaaaaa ccccaacgaa     1920

aucuacagcg agaucagcga agucgccaaa cucaaggacg caaaauccga ggucaaaaag     1980

ucucaauacu ucagcaccuu cacucuacgc ggcucauaca cgggcggcgc cuccaaaggc     2040

aaauuagaag accaaaaagc caugaacaag uuuaucgacg acagccucaa gaaacuugac     2100

accuacucgu ggaguggcua caaaacucua accgccuacu uuacaaacua caaagucgac     2160

ucguccaacc gcgugacaua cgacguaguc uuccacgggu accuaccgaa cgagggagac     2220

agcaaaaaca gccuccccua cggaaaaaua aacggcacau acaagggaac cgaaaaagag     2280

aaaauaaaau ucuccuccga aggcucguuc gaccccgaug guaagauagu auccuacgaa     2340

ugggacuucg gagacggcaa uaaaagcaau gaggaaaacc cagaacacuc auacgacaaa     2400

guagggaccu acaccguuaa auuaaaaguc acggacgaca aaggagaguc gagcgucuca     2460

accaccaccg ccgagauaaa agaccuaucc gaaaacaaac uacccguaau cuauaugcac     2520

gucccaaaau caggcgcacu caaucaaaag guugucuucu auggaaaagg caccuacgac     2580

ccggacggca gcauagcggg cuaccaaugg gacuuuggcg acgguucgga cuucucguca     2640

gagcaaaacc cuagccaugu auacaccaag aaaggagaau acaccguaac ccugcgagug     2700

auggauucau cuggccaaau gucugagaaa acaaugaaaa uaaaaaucac cgacccagua     2760

uaccccaucg guaccgaaaa agaaccuaac aacaguaaag aaacugcaag cggacccauc     2820

guccccggca uuccugucuc aggaaccauc gaaaacacca gcgaucagga cuacuucuac     2880

uuugauguaa ucacccccgg cgaagucaaa aucgacauca acaaacuagg auacggcgga     2940

gccacauggg uggucuacga cgagaacaau aacgccgucu cuuacgcaac cgacgaugga     3000

caaaaccuca gcgguaaauu uaaagcagac aagcccggac gcuacuacau ccaccuauac     3060

auguuuaacg gcuccuacau gcccuaucga auuaacauug agggcucagu aggccgcuga     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  2133
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt8)

<400>  2133
gggagaaagc uuaccaugaa aagaaaaugc cuauccaaac gccucaugcu ugcaauaaca       60

auggccacaa uauuuaccgu caacuccacc cuaccaaucu acgccgccgu agauaaaaac      120

aacgcaacag cagccgucca aaacgagagc aaacgauaca ccguaucaua ccucaagacc      180

cuaaacuauu acgaucuagu ggaccuccuc guaaagacgg agaucgaaaa cuuaccggau      240

cuauuucaau acuccuccga cgcaaaagag uucuacggua acaagacacg aauguccuuc      300

aucauggacg aaaucggacg gcgcgcaccc caauacaccg aaaucgacca caaaggcaua      360

cccacccuug ucgaaguugu acgagccggc uucuacuuag gauuccacaa caaggaacuc      420

aacgaaauca acaaacgcuc cuucaaagaa cgagucaucc ccuccauccu cgcuauucag      480

aagaacccaa acuucaagcu cgggaccgag guacaagaua agauagucag cgccaccggc      540

cugcuggccg gcaaugagac cgcgccccca gagguaguaa acaauuucac cccaauccua      600

caagauugca ucaagaauau cgaccgcuac gcccuggacg accuaaaauc caaggcccuc      660

uucaacgugc uggccgcgcc caccuacgau aucaccgaau accucagagc uaccaaagag      720

aaacccgaga acacucccug guauggcaag auagacggcu uuauaaacga acucaaaaag      780

cuagcacugu acggcaagau caaugauaac aauucaugga ucaucgacaa cgggauauac      840

cacauugccc cguuagguaa acugcacagc aacaauaaaa uaggaaucga gacccuaacu      900

gaggucauga aaguauaucc cuaucuuagc augcaacacc uacaauccgc ggaccaaauc      960

aagcgccacu acgacagcaa agacgcugag gggaacaaaa ucccccugga caaguucaag     1020

aaagagggca aggagaaaua cugcccaaaa accuacaccu ucgacgacgg caaagucaua     1080

aucaaagccg gcgcgagagu agaggaagaa aaaguaaagc ggcucuacug ggccagcaaa     1140

gaagucaaca gucaauucuu ccgcgucuac ggcaucgaua aaccacuaga agagggaaau     1200

cccgacgaca uacuaacaau gguaauauac aacagcccag aggaguacaa acugaacucc     1260

guccuuuacg gauacgauac aaacaacggg ggaauguaua uagaaccgga aggcacauuu     1320

uucaccuacg aacgcgaggc ccaggaauca acauauacac ucgaggaguu auuccgccac     1380

gaauacaccc acuaccuaca gggacgcuac gcaguaccag ggcagugggg ccgcacaaag     1440

cucuacgaua acgaccgccu aacgugguac gaagaagggg gcgccgaacu cuucgccgga     1500

uccacccgca ccagcgggau ccuaccgcga aagaguauag ugagcaacau ccauaacacc     1560

acgcgcaaca accgcuacaa gcucucagac acaguccaca gcaaguacgg agcaucguuc     1620

gaguucuaca acuacgcaug uauguucaug gacuacaugu acaacaaaga caugggcauc     1680

cucaacaaac ucaacgaucu cgcgaaaaau aacgacgucg acggauacga caacuauauc     1740

cgcgaccucu cauccaacua cgcacucaac gacaaauacc aagaccacau gcaggaacga     1800

auagacaacu acgaaaauuu aaccguacca uucguagccg acgacuaccu aguacgacac     1860

gccuacaaaa acccuaacga aaucuacucc gagaucuccg aaguugccaa acucaaagau     1920

gccaaaucag aagucaagaa aucccaguac uucagcacau ucacucugag aggcagcuac     1980

acgggcggcg cguccaaagg aaaacuagaa gaucagaaag ccaugaacaa auucaucgac     2040

gacucucuaa agaaacucga cacauacucg uggagcgguu acaaaacacu gacugccuac     2100

uuuaccaacu acaaagucga caguucaaau cgagucaccu acgacguggu auuucacggu     2160

uaccuaccca acgaagggga cuccaaaaac ucacuaccuu acggaaaaau aaaugggacc     2220

uacaaaggca cagaaaaaga gaaaaucaaa uucuccuccg aaggcagcuu cgacccugac     2280

ggaaagaucg ugagcuauga augggacuuc ggcgacggca acaaaucaaa cgaagaaaac     2340

cccgagcauu cauaugacaa gguaggaacc uacacaguca agcugaaagu aaccgacgac     2400

aaaggggaau caagcguaag cacuaccacc gccgagauca aggacuuaag cgaaaacaaa     2460

cugccaguaa uuuauaugca cgucccaaaa ucaggcgccc uaaaccagaa ggugguauuu     2520

uacgguaaag ggacguacga ucccgacggc agcaucgccg gcuaucagug ggacuucggu     2580

gacggcagcg acuucucaag cgaacaaaac cccagccacg uuuacacgaa aaagggcgaa     2640

uacacaguga cacuuagagu cauggauagc ucgggucaaa ugagugagaa aacgaugaaa     2700

auaaagauca ccgaccccgu guaccccauc ggcaccgaaa aggaaccgaa caacucaaaa     2760

gaaaccgccu ccgggcccau cguacccggg aucccuguau cuggcacaau agaaaacaca     2820

agcgaccaag acuacuucua cuucgacguc auaacccccg gcgaagucaa aaucgauauc     2880

aacaaacucg gauacggcgg agcgacaugg guaguguacg acgaaaacaa caacgcagua     2940

uccuacgcca cagacgacgg ccaaaaccuc uccggcaaau ucaaggccga caagcccgga     3000

cgauacuaca uacaccucua cauguucaac ggaucauaca ugcccuaccg gauaaacauc     3060

gaaggaucgg ugggacggua aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  2134
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt8)

<400>  2134
gggagaaagc uuaccaugaa augggucaca uuuaucagcc uccuuuuccu uuucagcucg       60

gccuacagcg uccaaaacga aaguaaaaga uauaccguau ccuaucucaa aacuuuaaac      120

uauuacgacc uaguagaccu ccugguaaag acugaaauag aaaaccugcc agaccuauuc      180

caauacagcu ccgacgcuaa ggaguucuac gggaacaaaa cccgcauguc cuucaucaug      240

gacgaaaucg ggcgacgcgc accacaguac accgaaauag accacaaagg gauucccacu      300

cuagucgagg ugguacgagc cggauuuuac cuuggauucc acaacaaaga acucaacgaa      360

auaaauaagc gaucauucaa agagcggguu aucccaagca uacuggcaau ccaaaagaau      420

ccaaacuuca aacuuggcac agaaguccag gacaaaauag ucuccgccac cgggcuccuc      480

gccgggaaug aaaccgcacc cccagaaguc gugaauaacu ucacccccau ucuccaggac      540

uguauaaaga acaucgaccg cuacgcacuc gacgaccuua agucaaaagc gcucuuuaac      600

guccucgcgg cgccuacaua cgacaucaca gaauaccuuc gcgcgaccaa ggaaaagcca      660

gaaaacaccc caugguacgg aaaaauagac ggguucauca acgaacuaaa gaaacuagcg      720

cuauacggca aaaucaacga caacaacagc uggaucauug acaacggcau auaucacaua      780

gcaccccugg gaaaacucca cagcaauaac aagaucggca ucgaaacccu aaccgaagua      840

augaaagucu acccguaccu cuccaugcag caucuccaga gcgccgacca gauaaaacga      900

cacuacgacu caaaagacgc agaagguaau aagaucccac uggacaaguu caaaaaggag      960

ggcaaagaaa aauacugccc uaaaacauac accuucgacg acggaaaggu aauaauuaaa     1020

gccggagcac gaguagaaga agaaaaagua aaacgccucu acugggccuc aaaggaaguu     1080

aauucacagu ucuuccgagu guacgguaua gacaaaccac uggaggaggg aaacccagau     1140

gacauacuga cgaugguaau auacaacucc ccggaagaau acaaacuaaa uucaguacug     1200

uacggauacg acaccaacaa ugggggaaug uacaucgaac cagaaggcac cuucuucacc     1260

uacgagcgcg aagcccagga gucgacauau acccuagaag aacuguuucg ccacgaguac     1320

acgcacuacu uacaagggcg cuacgccguc cccgggcagu ggggccgaac caaacuguac     1380

gacaacgacc gccucaccug guacgaagaa gggggagcag aacucuucgc aggaucgacc     1440

cgcaccagcg gaauacuccc ccgcaagagu auagucagca acauccacaa caccaccagg     1500

aacaacagau acaaacuuuc agacaccguu cacagcaagu acggggccuc cuucgaguuu     1560

uacaacuacg caugcauguu cauggauuau auguacaaca aagacauggg aauacuaaac     1620

aaacucaaug accucgccaa aaacaacgac gucgacggcu acgacaacua cauccgagac     1680

cucagcagca acuacgcccu aaacgacaaa uaucaagacc acaugcagga gaggauagau     1740

aacuacgaaa aucucaccgu gccauucgua gccgacgacu accucguacg ucacgccuac     1800

aaaaacccca acgaaaucua cagcgagauc ucggaaguag caaaacuaaa agaugcuaaa     1860

ucagagguga agaaauccca auacuucucg accuucacuc uccgcggcuc cuacacagga     1920

ggagccagca aagguaaacu agaggaccaa aaagcaauga acaaauucau cgacgacucc     1980

cucaagaaac ucgauaccua cagcuggagc ggauacaaaa cguuaaccgc auauuucacc     2040

aauuacaaag uggacaguuc caaccgagua accuacgaug uaguguucca uggcuaccua     2100

cccaacgagg gcgacagcaa aaacucacuc cccuacggaa agaucaacgg gacauacaag     2160

ggcacggaaa aagagaaaau caaauucagc ucagaaggcu ccuucgaccc cgacggcaag     2220

auugucuccu acgaguggga cuucggggac ggcaacaaau cgaacgagga gaacccagaa     2280

cacagcuacg acaaggucgg cacguacacc gucaagcuca aaguaacaga cgacaagggg     2340

gaauccagcg uaagcacgac aacagcagaa aucaaggacc uauccgaaaa uaaacuaccg     2400

gugauauaca ugcauguccc uaaauccggc gcucugaauc agaagguggu auucuacggg     2460

aagggcacgu acgaccccga cggauccaua gcaggcuacc aaugggacuu cggcgauggu     2520

ucggacuuuu cguccgagca gaacccaagc cacguauaca caaagaaagg ggaguauacc     2580

gucacacuuc gagucaugga cagcaguggc cagaugagug agaaaacaau gaaaaucaaa     2640

aucacagauc ccguuuaccc gaucggcaca gaaaaagaac caaacaauuc caaagagacg     2700

gcgucaggcc caaucgugcc cggaaucccc guuucgggaa ccauagagaa cacaagcgac     2760

caagacuacu ucuacuucga cgucaucacc ccaggcgagg uaaaaauaga cauaaacaaa     2820

cuaggauacg gaggcgcaac auggguggua uacgacgaaa acaacaacgc ggucagcuau     2880

gcaacggacg acggccaaaa ccuaucagga aaguucaagg ccgacaagcc cggaagguac     2940

uauauacauu uguacauguu caacggcagc uacaugcccu acagaaucaa caucgaaggc     3000

agcgucggcc gcugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2135
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt8)

<400>  2135
gggagaaagc uuaccaugaa augggugacc uucauaucac uccuuuuccu auucucauca       60

gcauacucga ugaaacgcaa augccucagc aaacgacuca ugcuagcuau caccauggcc      120

acaauauuca ccguaaacuc cacccuaccc aucuacgcgg caguggacaa aaacaacgcc      180

accgccgcac gucgccgccg gaaacgcguc caaaacgaaa guaagcgcua uacggugagc      240

uaccucaaaa cucucaacua cuaugaucua guagaccucc uagucaaaac ggaaauugaa      300

aaccuccccg accuauucca guacucauca gacgcgaaag aguucuacgg caacaaaacc      360

cggauguccu ucauaaugga cgaaaucgga aggcgagcac cccaguauac cgagaucgac      420

cacaagggca uccccacgcu cguagaagua guuagagcag gcuucuaccu cggguuccac      480

aacaaagaac uaaaugagau caacaaacgc uccuucaaag aacgcgucau ccccucaaua      540

cuagcaaucc agaaaaaccc caauuucaaa cuaggcaccg agguacaaga uaaaaucgug      600

uccgcaacag gccuccuggc agguaaugaa accgcgccgc cagaaguagu caacaacuuc      660

acacccaucc uucaggacug caucaaaaac auagacagau acgcacucga cgaccucaaa      720

agcaaagcac uauucaacgu ccucgcagca cccacauaug acauaacgga auaccuuaga      780

gcaaccaaag aaaaacccga aaacacaccc ugguauggga aaauagacgg cuucaucaac      840

gagcuuaaaa agcuggcacu uuacgggaaa auaaacgaca acaacagcug gaucauagac      900

aacggcauuu accacaucgc accccugggg aaauugcaca gcaacaacaa aaucggcaua      960

gaaacccuca cggaggucau gaaaguuuac ccauaccugu caaugcaaca ccuccaaucc     1020

gccgaccaga ucaaacgaca cuacgacagc aaagacgccg aaggcaacaa gauaccacua     1080

gacaaguuca agaaagaagg caaagaaaaa uauugcccua aaaccuacac auucgacgac     1140

ggaaaaguaa ucauuaaagc cggcgcccgu guagaagaag aaaaggucaa acgccuauac     1200

ugggccagca aagaaguaaa uagccaauuc uuccgcguau acgggauaga caaaccgcua     1260

gaagaaggaa accccgacga cauacugacc augguaauau auaacucacc ggaagaauac     1320

aaacucaaca gcguacuaua cggcuaugac accaauaacg gaggaaugua caucgagcca     1380

gaaggaacau ucuucacgua cgaacgugaa gcacaagaau ccacauacac ccucgaggaa     1440

cucuuccguc acgaguacac ccacuaccua caggggcgau acgccguacc cggccaaugg     1500

ggccgcacca aacuguauga caacgaccgg cucaccuggu acgaagaagg gggcgccgaa     1560

cucuucgccg guucgaccag gacuucagga auacugcccc gcaagagcau cguaagcaac     1620

auccacaaua caacccgcaa caaccgcuac aaacuaucag acacagucca cuccaaauac     1680

ggagcgucau uugaguucua caacuacgcu ugcauguuua uggauuauau guacaacaaa     1740

gauaugggga uccugaauaa acuaaacgac cuagcgaaaa acaacgacgu ugacggcuac     1800

gacaacuaca uacgugaccu cucaucaaac uacgcccuaa acgacaaaua ccaggaccac     1860

augcaagaac gcaucgacaa uuacgaaaac cuaacagugc cuuuugucgc cgacgacuac     1920

cucguacggc acgcuuacaa aaaccccaac gaaaucuauu cagaaaucuc agaagucgcc     1980

aaauuaaaag acgcuaaauc cgaagucaag aagucccaau acuucuccac auuuacccuc     2040

agaggcucau acaccggagg cgcauccaaa ggcaaacugg aggaccaaaa agccaugaac     2100

aaauucaucg augacagucu aaagaaacuc gacaccuacu ccugguccgg auacaaaacg     2160

cuaacagccu acuucacaaa cuacaaagua gacagcucca accgagucac cuacgacguc     2220

gucuuccaug guuaccuccc caacgaaggu gacagcaaaa auucacuccc cuacggcaaa     2280

auaaacggca ccuacaaagg caccgaaaag gagaaaauca aauucucauc ggaaggcagc     2340

uucgacccag acgggaagau aguaucguau gaaugggacu ucggggacgg caacaaaucc     2400

aaugaagaga accccgaaca uuccuaugac aaagugggga ccuacacagu uaagcuaaaa     2460

guaaccgacg acaaaggcga aucauccgua ucaaccacaa cggccgagau aaaagaucua     2520

agcgaaaaca aacuccccgu aauauacaug cacgucccua aaucgggagc ucucaaccaa     2580

aaagucguau ucuacggaaa aggaacauac gacccugacg gcuccauagc cggcuaccaa     2640

ugggacuuug gcgacggcag cgacuucucc agugagcaaa accccucaca cgucuacacg     2700

aaaaagggcg aauacaccgu gacacuucgc guaauggaca gcagcggcca gauguccgag     2760

aaaaccauga aaaucaagau uaccgaccca gucuacccca uaggcaccga aaaggaaccg     2820

aacaauagca aggaaacagc cagcggccca auagucccgg ggauccccgu cuccggcacg     2880

aucgaaaaca cuuccgacca ggacuacuuc uacuucgacg uaauaacccc cggcgaagua     2940

aaaaucgaca ucaacaaacu aggauacgga ggcgccaccu gggucgucua cgaugaaaac     3000

aacaacgccg uauccuaugc cacagacgau ggccagaacu ugucaggcaa guucaaagcu     3060

gacaagcccg gacgcuacua cauccaccug uacauguuca auggcuccua caugccauac     3120

cgaauaaaca ucgaaggauc ggucggacgc ugaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  2136
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt8)

<400>  2136
gggagaaagc uuaccauggg caccuggauc cuauucgcau gccuccucgg agccgccuuc       60

gccaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc uuacgaaguc      120

cucacccccc uaaaauggua ccaaucaauu cgcccccccu auccauccua cggcuacgaa      180

cccaugggcg gcuggcuaca ccaccaaaua auacccgucc ucucccaaca acaccccccc      240

acccacaccc uccaacccca ccaccacauc cccgucgucc ccgcacaaca acccgucauc      300

ccccaacaac caaugaugcc agucccaggc caacacucua ugacccccau ccaacaccac      360

caacccaacc uccccccccc cgcacaacaa ccauaccaac cccaacccgu ccaaccacaa      420

ccccaccaac ccaugcaacc ccaacccccc guccacccca ugcaaccccu cccaccccaa      480

ccaccccucc cccccauguu ccccaugcaa ccccuccccc ccaugcuacc cgaccuaacc      540

cucgaagccu ggcccuccac agacaaaaca aaacgagaag aagucgacua aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  2137
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt8)

<400>  2137
gggagaaagc uuaccaugcc ccucccaccc caccccggcc accccggaua cauaaacuuc       60

uccuacgaag uccuaacacc ccuaaaaugg uaccaaucca uacgcccacc cuaccccucc      120

uacggcuacg aacccauggg cggaugguaa ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  2138
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt8)

<400>  2138
gggagaaagc uuaccaugcc ccucccaccc caccccggcc accccggcua cauaaacuuc       60

uccuacgaag uccucacacc acucaaaugg uaccaaucca uccgcccacc acccaugcuc      120

cccgaccuca cccucgaagc cuggcccucc accgacaaaa caaaacgcga agaagucgac      180

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  2139
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt8)

<400>  2139
gggagaaagc uuaccauggc cgucauggca ccccgaaccc uaguccuacu ccuauccggc       60

gcccuagccc ucacccaaac cugggccaug ccacuaccac cccacccagg ccaccccggc      120

uacaucaacu ucuccuacga aguacucaca ccacuaaaau gguaccaauc cauccgacca      180

cccuaccccu ccuacggcua cgaacccaug ggcggcuggu aaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  2140
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt8)

<400>  2140
gggagaaagc uuaccauggc cguaauggca ccccgaacac ucguacuccu ccucuccgga       60

gcacuagccc ucacccaaac cugggccaug ccccuccccc cacaccccgg ccaccccggc      120

uacauaaauu ucuccuacga aguccucacc ccccucaaau gguaccaauc cauccgcccc      180

ccccccaugc uccccgaccu aacacucgaa gccuggcccu caaccgacaa aacaaaacgc      240

gaagaagucg acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  2141
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt8)

<400>  2141
gggagaaagc uuaccauggg caccuggauc cuauucgcau gccuagucgg cgccgccuuc       60

gccaugcccc ucccacccca ccccggccac cccggcuaca ucaacuucuc cuacgaagua      120

cucaccccac ucaaauggua ccaauccaug auacgcccac ccuacuccuc cuacggauac      180

gaacccaugg gcggcuggcu ccaccaccaa auaauccccg ucguuuccca acaacacccc      240

cucacccaca cccuccaauc acaccaccac auccccguag uccccgccca acaaccccga      300

guccgccagc aagcccucau gcccguacca ggccaacaau caaugacccc cacccaacac      360

caccaaccca accucccccu ccccgcccaa caacccuucc aaccccaacc cguccaaccc      420

caaccacacc aaccaaugca accccaacca cccguccaac ccaugcaacc ccuucucccc      480

caaccucccc uaccacccau guucccccuc cguccucucc cacccauccu ccccgaccuc      540

caccucgaag ccuggcccgc caccgacaaa accaaacaag aagaaguaga cugaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  2142
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt8)

<400>  2142
gggagaaagc uuaccaugcc ccuaccaccc caccccggcc accccggcua cauaaacuuc       60

uccuacgaag uccucacccc acucaaaugg uaccaaucaa ugauacgacc acccuacucc      120

ucauacggcu acgaacccau gggcggcugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  2143
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt8)

<400>  2143
gggagaaagc uuaccaugcc ccucccccca caccccggcc accccggcua cauaaacuuc       60

uccuacgaag uccuaacacc acucaaaugg uaccaaucca ugauccgccc cccccccaua      120

cuccccgacc uccaccucga agccuggccc gccacagaca aaaccaaaca agaagaaguc      180

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  2144
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt8)

<400>  2144
gggagaaagc uuaccauggc cgucauggcc ccacgcacac ucguccuccu acucucagga       60

gcccucgcac ucacacaaac cugggccaug ccacucccac cacaccccgg ccaccccggc      120

uacaucaacu ucucauacga aguccucacc ccacucaaau gguaccaauc aaugauacgc      180

ccacccuacu ccuccuacgg cuacgaaccc augggcggau gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  2145
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt8)

<400>  2145
gggagaaagc uuaccauggc agucauggca ccccgcaccc ucguccuacu acucuccggc       60

gcccucgccc ucacccaaac augggccaug ccacucccac cccaccccgg acaccccggc      120

uacaucaacu ucucauacga aguccucacc ccacucaaau gguaccaauc caugauccga      180

cccccaccca uccuacccga ccuccaccuc gaagccuggc ccgccaccga caaaaccaaa      240

caagaagaag ucgacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  2146
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt8)

<400>  2146
gggagaaagc uuaccauggg caccuggauc cucuucgcau gccuccucgg cgccgccuuc       60

uccaugccuc uaccacccca ccccggccac cccggcuaca uuaacuucuc cuacgaaguc      120

cuaacucccc uaaaauggua ccaaaacaug auccgacacc ccuacaccuc cuacggauac      180

gaacccaugg gcggauggcu ccaccaccaa aucauccccg ucgucuccca acaaacaccc      240

caaucccacg cccuacaacc ccaccaccac auccccaugg uacccgccca acaacccggu      300

auaccccaac aacccaugau gccccucccc ggccaacacu caaugacccc cacccaacac      360

caccaaccca accuaccccu acccgcacaa caacccuucc aaccccaacc aguccaaccc      420

caaccccacc aaccacucca accccaaucc cccaugcacc ccauccaacc ccuccuccca      480

caaccacccc ucccacccau guucuccaug caaucacucc uccccgaccu cccccucgaa      540

gccuggcccg caaccgacaa aaccaaacgc gaagaagucg acuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  2147
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt8)

<400>  2147
gggagaaagc uuaccaugcc ccuaccaccc cacccaggcc accccggcua caucaacuuc       60

uccuacgaag uccucacacc acucaaaugg uaccaaaaca ugaucagaca cccauacacc      120

ucauacggcu acgaacccau gggcggcugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  2148
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt8)

<400>  2148
gggagaaagc uuaccaugcc acuaccccca caccccggcc accccggcua cauaaacuuc       60

ucauacgaag uacucacccc acucaaaugg uaccaaaaca ugauccgaca ccccucccuc      120

cuccccgacc ucccccucga agccuggccc gccaccgaca aaaccaaacg cgaagaaguc      180

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  2149
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt8)

<400>  2149
gggagaaagc uuaccauggc agucauggca ccccgcacac ucguccuccu acuaucagga       60

gcccucgcac ucacacaaac augggccaug ccccuaccac cccaccccgg acaccccggc      120

uacauaaacu ucuccuacga aguccuaaca ccccuaaaau gguaccaaaa caugauccga      180

caccccuaca ccuccuacgg cuacgaaccc augggcggcu gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  2150
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt8)

<400>  2150
gggagaaagc uuaccauggc cgucauggcc ccacgcaccc uaguccuccu ccuauccggc       60

gcacucgcac ucacacaaac cugggccaug ccccucccac cacaccccgg ccaccccggc      120

uacaucaacu ucuccuacga aguccucaca ccccucaaau gguaccaaaa caugauccgc      180

cacccaucac uccucccaga ccucccacuc gaagccuggc ccgccaccga caaaaccaaa      240

cgcgaagaag uagacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  2151
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt8)

<400>  2151
gggagaaagc uuaccauggg caccuggaua cucuucgcau gccuccucgg cgccgccuuc       60

uccaugcccc ucccacccca ccccggccac cccggcuaca ucaacuucuc cuacauccgc      120

cacccauaca ccuccuacgg cuacgaaccc augggcggcu ggcuacacca ccaaaucauc      180

cccgucgucu cccaacaaac accccaaucc cacgcccuac aaccccacca ccacauccca      240

augguccccg cccaacaacc aggcauccca caacaaccca ugaugccccu acccggccaa      300

cacucaauga ccccaacuca acaccaccaa cccaaccuac cccuacccgc ccaacaaccc      360

uuccaacccc aacccgucca accccaaccc caccaacccc uccaacccca aucccccaug      420

caccccaucc aaccccuccu accccaacca ccccucccac ccauguucuc aaugcaaucc      480

cuacuccccg accuaccccu cgaagcaugg cccgcuacag acaaaacaaa acgcgaagaa      540

gucgacuaag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  2152
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt8)

<400>  2152
gggagaaagc uuaccauggg aaccuggauc uucuucgccu gccuccucgg cgccucccuc       60

gcaaugcccc ucccacccca ccccggccac cccggcuaca ucaacuucuc cuaugaagua      120

cucacacccc ucaaauggua ucaaaacaug auccgccacc ccuacacauc cuacggcuac      180

gaacccaugg gcggcuggcu acaccaccaa aucauacccg ucgucucaca acaaacaccc      240

caaucacacg cccuccaacc ccaccaccac auccccaugg uccccgccca acaacccggc      300

aucccccaac aacccaugau gccccuacca ggacaacacu ccaugacccc aacccaacau      360

caccaaccua aucucccccu ccccgcccaa caacccuucc aaccccaacc cguccaaccc      420

caaccccacc aaccccucca accccaaucc cccaugcacc cuauccaacc ccuccucccc      480

caaccacccc ucccacccau guucuccaug caaucacucc uacccgaccu cccccucgaa      540

gccuggccug ccaccgacaa aacaaaacgc gaagaagucg acuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  2153
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt8)

<400>  2153
gggagaaagc uuaccauggg caccuggaua cucuucgccu gccuccucgg cgccgcauuc       60

ucaaugcccc ucccaccaca cccaggccac cccggauaca ucaacuucuc cuacgaagua      120

cucaccccac ucaaauggua ccaaaacaug auccgacacc ccucacuccu ccccgaccuc      180

ccccuagaag ccuggccagc caccgacaaa accaaacgcg aagaagucga cuaaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  2154
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt8)

<400>  2154
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccuccuagg cgcugccuuc       60

uccaugccac ucccacccca ccccggccac cccggcuaca ucaacuucuc cuacgaagac      120

cuauaccucg aagccauacg caucgaccgc accgcauuug uccuaacccc acucaaaugg      180

uaccaaaaca ugauccgaca cccauacacc uccuacggcu augaacccau gggaggcugg      240

cuacaccacc aaaucauccc agucgucuca caacaaaccc cucaaucuca cgcccuccaa      300

ccacaccacc acauccccau gguccccgcc caacaacccg gcauccccca acaacccaug      360

augccccucc ccggccaaca cuccaugacc cccacccaac accaccaacc caaccucccc      420

cuccccgcac aacaacccuu ccaaccccaa ccaguccaac cccaaccaca ccaaccccuu      480

caaccccaau cccccaugca ccccauccaa ccccuccuac cacaaccacc cuuaccuccc      540

auguuuucua ugcaaucccu ccuccccgac cucccccucg aagccuggcc cgccaccgac      600

aaaacaaaac gcgaagaagu agacuaagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  2155
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt8)

<400>  2155
gggagaaagc uuaccauggg aaccuggauc cuauucgccu gccuccuagg agccgccuuc       60

ucaaugcccc uaccacccca ccccggccac cccggcuaca ucaacuuuuc cuacgaaguc      120

cucaccccac ucaaauggua ccaaaacaug auacgccacc ccacacccca aucccacgcc      180

cuacaacccc accaccacau ccccaugguc cccgcccaac aacccggcau cccccaacaa      240

cccaugaugc cccuccccgg ccaacacucc augaccccca cccaacacca ccaacccaac      300

cucccccucc ccgcccaaca acccuuucaa ccccaacccg uccaacccca accacaccaa      360

ccacuccaac cccaaucccc caugcaccca auccaacccc uccuccccca accaccccuc      420

ccacccaugu ucucaaugca aucacuacuc cccgaccucc cccucgaagc cuggcccgcc      480

accgacaaaa ccaaaagaga agaagucgac uaaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  2156
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt8)

<400>  2156
gggagaaagc uuaccaugcc ucucccaccc caccccggcc accccggcua caucaacuuc       60

uccuacgaag uccucacacc ccucaaaugg uaccaaaaca ugauccgcca ccccuacacc      120

ucauacggcu acgaacccau gggcggcugg cuccaccacc aaaucauccc cgucgucucc      180

caacaaacac cccaaucaca cgcacuccaa ccccaccacc acauccccau gguccccgcc      240

caacaacccg gcauccccca acaacccaug augccacucc ccggccaaca cucaaugacc      300

cccacccaac accaccaacc caaccuccca cuccccgcac aacaacccuu ccaaccacaa      360

cccguacaac cccaacccca ccaaccacuc caaccccaau cccccaugca ccccauccaa      420

ccccuacucc cccaaccacc ccuaccccca auguucucaa ugcaaucccu ccuccccgac      480

cucccccucg aagcauggcc agccacagac aaaaccaaac gcgaagaagu cgacuaagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  2157
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt8)

<400>  2157
gggagaaagc uuaccaugcc aggcguugca agacuaccac uacucuuagg acuacuacua       60

cuaccgcgac caggacgacc ccucgaccua gcagacuaca ccuaugaccu cgccgaagaa      120

gaugauagcg aaccgcuaaa uuacaaagac ccguguaaag cagcagcuuu ucuaggcgac      180

auagcccugg acgaggaaga ccuucgggcg uuccaaguac aacaggcagu agauuuacgc      240

cgacacacgg cucgaaaauc aucaaucaaa gcagccguuc caggaaacac gucaacccca      300

agcugucagu caacaaaugg gcaaccccaa cgcggagcgu gcggacgaug gcgaggccgc      360

agcagguccc gcagagcagc caccucccgc cccgaaagag ucuggcccga uggaguaaua      420

ccguucguaa uaggcggcaa uuucaccgga ucccagcgcg cggucuuccg ccaagccaug      480

agacacuggg agaaacauac cugcgugaca uuccucgaaa gaacagacga agacucauac      540

auaguauuca ccuaccgacc gugcggcugc ugcagcuacg uaggccgcag aggcggcggg      600

ccacaagcga ucagcaucgg caaaaacugc gacaaauucg gaauagucgu ccacgaacuc      660

ggccacguag uaggcuucug gcacgagcac acccgaccug accgagaccg acacgucagc      720

aucguaagag aaaacauaca accagggcaa gaauacaacu uccugaaaau ggagccccaa      780

gaaguggaau ccuuaggaga aaccuacgac uuugacucaa ucaugcacua cgcaaggaac      840

acauucucac gaggaauauu ccucgacaca auaguuccca aguacgaagu gaacgggguu      900

aaaccuccga uuggccaaag gacaagacua ucaaagggcg acaucgcaca ggcacgaaaa      960

cuguacaaau gccccgcaug cggggagaca cuacaagaca gcaccgggaa cuucucaagu     1020

ccggaauacc caaacggaua cagugcucac augcacugcg uauggcggau aagcgucacc     1080

ccgggcgaga aaauaauacu aaacuucaca agucuggacc uauaccggag ccgccuuugc     1140

ugguacgauu acguagaagu ccgcgacgga uucuggcgca aagcgccacu gaggggacgc     1200

uucugcggau caaaacuccc ggaaccgaua guaucaaccg acucacgccu cugggucgag     1260

uucagaagca gcucaaacug ggucggaaaa ggauucuuug caguguacga agcuaucugc     1320

ggaggagacg uaaagaaaga cuaugggcac auacaaagcc ccaacuaccc cgacgacuac     1380

cgcccuagca aaguuugcau cuggcgcaua caagucagcg aaggcuucca cgucggccug     1440

acauuccaga guuucgaaau agaacgccau gacagcugcg ccuacgauua ccucgaaguc     1500

cgcgacggcc acucggaaag cagcaccuua aucggcaggu acugcgguua cgaaaaacca     1560

gacgacauaa agagcaccuc gagccgacuc uggcuaaaau ucguaagcga cggcagcaua     1620

aacaaagcgg gcuuugcagu uaacuucuuc aaagaagugg acgaaugcuc caggccaaac     1680

cgaggcgggu gcgaacaaag augucuaaau acacucggca gcuacaaaug cagcugcgac     1740

ccgggauacg aacucgcccc cgacaaaaga aggugcgaag ccgccugcgg aggguuccuc     1800

acaaaacuaa acgggagcau cacuucaccg ggauggccaa aagaauaccc accaaauaag     1860

aacugcaucu ggcaacucgu cgcacccacc caauaccgca ucagccuaca auucgacuuc     1920

uucgaaaccg aaggcaacga cgucugcaaa uacgacuucg uugaaguccg cuccggacua     1980

acagcagaca gcaaacuaca cgguaaauuc ugcggcuccg aaaagccaga agucauaaca     2040

agccaauaca acaauaugag agucgaguuc aagagcgaca acaccgucag caaaaaggga     2100

uuuaaggcac acuucuucuc agacaaagac gaaugcucaa aagacaacgg cggcugccaa     2160

caagacugcg uuaacacauu cggcucauac gaaugccaau gcagaucagg uuucgugcug     2220

cacgacaaca aacacgacug caaagaagcc ggcugcgacc auaaaguuac cagcaccagu     2280

ggaaccauaa caagccccaa cuggccagac aaauacccau cgaagaaaga augcacgugg     2340

gcuaucucca gcacacccgg gcaccggguc aaacucaccu ucauggaaau ggauaucgaa     2400

agccaaccgg aaugcgcaua cgaccaucua gaagucuuug acggccgaga cgccaaagcc     2460

ccaguacucg gcagauucug cggauccaag aaaccagaac caguacucgc gaccgggagc     2520

cgaauguucc uccgcuucua cagcgacaac uccgugcaac gcaaaggcuu ccaagccucc     2580

caugcgacgg aaugcggcgg acaaguucgc gcggacguca aaaccaaaga cuuauacagc     2640

caugcacagu ucggugacaa caauuacccc ggaggcguag acugcgaaug ggucauagua     2700

gccgaagaag gauacggcgu cgagcucgua uuccagacau ucgaaguaga agaagaaacc     2760

gacugcggcu acgauuacau ggaacuuuuc gacggguacg acagcacagc gccacgccuc     2820

ggacgcuacu gcggaucagg cccgccagaa gaaguauaca gcgcaggcga cuccguccua     2880

gucaaauucc auucugauga caccaucaca aagaaaggcu uccacuugag auacacaagu     2940

acaaaauucc aagacaccuu acauucaaga aaauaaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  2158
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt8)

<400>  2158
gggagaaagc uuaccauggu cgccggaacu cgcugccucc uagcccuccu acucccccaa       60

guacuacucg gcggcgccgc cggccucguu cccgaacucg gacgacgaaa auucgccgcc      120

gcauccucug gaaggcccag cucccaaccc uccgacgaag uucucuccga guucgaacuc      180

cgccuccucu caauguucgg ccucaaacaa cgccccacac caucacgcga cgcagucguc      240

ccgcccuaca ugcucgaccu auaccgucgu cacucaggcc aacccggauc ccccgccccc      300

gaccaccguc ucgaacgcgc agccucgcgc gccaacacag uccgcuccuu ccaccacgaa      360

gaaucccucg aagaacuacc cgaaaccucc ggcaaaacaa cccgacgcuu cuucuucaac      420

cucagcucca uccccacaga agaguucaua accuccgccg aacuacaagu auuccgcgaa      480

cagaugcaag acgcccucgg aaacaacagc ucauuccacc acagaaucaa cauuuacgaa      540

auaaucaaac ccgccaccgc gaacagcaaa uuucccguca cccgucuccu cgacacccgc      600

cucgucaacc aaaacgccuc ccgcugggaa ucuuuugacg uaacacccgc agucaugcgc      660

uggacagcac aaggccacgc caaccacgga uucgucguag aaguagccca ccuagaagaa      720

aagcaaggag uauccaaacg ucacguacga auaucacgcu cccuacacca agacgaacac      780

uccugguccc aaauccgacc ccuacucguc accuucggcc acgacggaaa aggacacccc      840

cuucacaaaa gggaaaaacg ccaagccaaa cacaaacaac gcaaacgacu caaauccuca      900

ugcaaaagac acccccucua cguugauuuc ucagacgucg gcuggaacga cuggaucgua      960

gccccacccg gcuaccacgc cuucuacugc cacggcgaau gccccuuccc ccucgcagac     1020

caccuuaauu caaccaacca cgcaaucguc caaacccucg ucaacuccgu caacucaaaa     1080

auccccaaag ccugcugcgu ccccaccgaa cuaucagcca ucuccauguu auaccuagac     1140

gaaaacgaaa aagugguccu caaaaacuac caagacaugg ucgucgaagg uugcggcugc     1200

cgauaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  2159
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt8)

<400>  2159
gggagaaagc uuaccaugau acccggcaac cgcaugcuca uggucguccu ccucugccaa       60

guacuccucg gaggagccuc acacgccuca cucauaccag aaacuggcaa aaaaaaaguc      120

gcugaaaucc aagggcacgc cggcggccgc cgcuccggcc aaucccacga acuucuuaga      180

gacuucgaag ccacccuacu ccaaauguuc ggacuccgcc gccgccccca acccuccaaa      240

ucugcaguua uacccgacua caugcgcgac cuauaccguc uacaaucagg cgaagaagaa      300

gaagaacaaa uccauaguac cggccucgaa uaccccgaac gccccgccuc ccgcgcaaau      360

acaguccgcu cauuccauca cgaagaacac cucgagaaca uccccggaac guccgaaaac      420

uccgccuucc gauuccucuu caaccuauca uccauccccg aaaacgaagu caucuccucc      480

gccgaacucc gccuuuuccg cgaacaaguc gaccaaggcc ccgacuggga acgcggcuuc      540

caccgcauaa acaucuacga aguaaugaaa ccacccgccg aggucguccc cggacaccuu      600

aucacacgcc uccucgacac ccgacuaguc caccacaacg ucacccgaug ggaaaccuuc      660

gacguauccc ccgcaguccu ccgcuggacc cgcgaaaaac aacccaacua cggacucgcc      720

auagaaguua cacaccucca ccaaacccga acacaccaag gccaacacgu ccgaaucucc      780

cgcucccucc cacaaggcuc cggcaacugg gcccaacucc gcccccuccu cguaaccuuc      840

ggacacgacg gacgcggaca cgcccucacc cgacgccgcc gagccaaacg cucccccaaa      900

caccacucac aaagagccag gaaaaaaaau aaaaauugcc gccgccacuc acucuacgua      960

gacuucagcg acgucggcug gaacgacugg auagucgccc cccccggcua ccaagcauuc     1020

uacugccaug gcgacugccc cuucccacuc gccgaucacc uaaacagcac caaccacgcc     1080

auaguccaaa cccuaguaaa cuccgucaac uccagcauac ccaaggcaug cugcguaccc     1140

acagaacuga gcgcaaucuc cauguuauac cucgacgaau acgacaaagu aguacucaaa     1200

aacuaccaag aaaugguagu agaaggaugc ggcugccgcu aaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  2160
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt8)

<400>  2160
gggagaaagc uuaccaugcc cggauuaggu cgccgagcac aguggcucug cugguggugg       60

ggacuccucu guagcugcug cggacccccc ccccuacgcc caccucuccc cgccgcugcc      120

gccgccgccg ccggcggcca acuacucgga gacggcggau cacccggccg aacugaacaa      180

ccaccccccu caccccaauc cucaagcggg uuccucuacc gucgccugaa aacccaagaa      240

aaacgcgaaa ugcaaaaaga aauccuaucc guccucggcc ucccccaccg cccccgcccc      300

cuacacggac ugcaacaacc ccagccacca gcccuacguc aacaagaaga acagcagcaa      360

caacaacaau uaccaagagg agaaccaccc ccuggccgac ugaaauccgc cccacuauuc      420

augcucgacc uauacaacgc acucagcgca gacaaugacg aagacggcgc aucagaagga      480

gaaagacaac aaucauggcc acacgaagca gccucaagcu cccaacgaag acaaccacca      540

cccggagcag cgcacccccu aaaccgcaaa ucccuacugg cccccggauc cggcagcggc      600

ggcgccuccc cacuaaccag cgcccaagac ucugcauucc uuaacgacgc agacaugguc      660

augucauucg uuaaccuggu cgaauacgac aaagaauucu cgccccgaca acgacaucac      720

aaggaauuca aauucaaccu cagccagaua cccgaaggcg aaguagucac cgccgccgag      780

uuccgcaucu auaaagacug cgucauggga ucauucaaaa accaaacauu ccuaaucucc      840

aucuaccaag uacuccaaga acaccagcac cgcgacagcg accucuuccu auuagacacc      900

cgcguagucu gggccucaga agaaggcugg cucgaauucg acauaacugc caccucaaau      960

cuuugggucg ucacaccaca acacaacaug ggccuccaac ucuccguagu cacccgugac     1020

ggaguccacg uacacccccg agcugccggc cucgucggac gagacggccc cuacgacaaa     1080

caacccuuca uggucgcauu cuucaaaguc uccgaagucc acguccgaac cacccgcuca     1140

gccuccuccc gucgcaggca acaaucccga aaccgaucca cacaauccca agauguagcc     1200

agaguauccu ccgccuccga cuauaacucc uccgaacuca aaacagcaug ccgcaaacac     1260

gaacucuaug uauccuucca agaccuugga uggcaagacu ggaucaucgc cccaaaagga     1320

uacgccgcca acuacugcga cggcgaaugu ucauucccuc uaaacgccca caugaacgca     1380

accaaccacg ccaucguaca aacacuuguc caccucauga aucccgagua cguccccaaa     1440

cccugcugcg cacccaccaa acucaacgcc auaucagucu uauacuucga cgacaacuca     1500

aacguaaucc ugaaaaaaua ccgcaacaug gucguucgcg caugcggcug ccacuaagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  2161
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt8)

<400>  2161
gggagaaagc uuaccaugca cguccguucc cugagagccg ccgcccccca cucguuuguc       60

gcccuauggg caccccuauu ccuccuucga ucagcacuug cagacuucuc ccuugacaac      120

gaaguccacu cguccuucau ccaccgccgc cucagaucac aagaacgacg agaaaugcaa      180

cgcgaaauac uuagcauccu aggccucccc caccgucccc gaccacaucu ccaaggcaaa      240

cacaacucag ccccaauguu caugcucgac cucuacaacg ccauggccgu cgaagagggc      300

ggcggacccg gcggucaagg cuucuccuac ccauacaaag ccgucuucag cacucaagga      360

ccaccccucg cuucccuuca agacucccac uuccuaaccg acgcagauau ggucaugucc      420

uucgucaacc uagucgagca cgacaaagaa uucuuccacc cccgcuacca ccaccgagaa      480

uuccgcuucg accucuccaa aauacccgaa ggcgaggccg ucacagcugc cgaauuccgc      540

aucuacaaag acuacauccg cgaacgcuuc gacaacgaaa ccuucaggau cucagucuau      600

caaguccuac aagaacaucu cggccgcgaa uccgacuuau uccuccuaga cucacgcacc      660

cucugggccu cagaagaagg auggcucgua uucgacauca cagccacauc aaaccacugg      720

gucgucaacc cccgccacaa ccucggccug cagcuaucag uagaaacccu cgacggacaa      780

uccaucaacc ccaaacucgc cggucucauc ggccgacacg gcccacaaaa caaacagccc      840

uucauggucg ccuucuucaa agccaccgaa guccacuucc gaagcauccg cuccaccgga      900

uccaaacaac gcucccagaa ucguuccaaa accccgaaaa accaagaggc ccuacgcaug      960

gccaacgucg cagaaaacuc cucaucagac caacgccaag ccugcaaaaa acacgaacua     1020

uacgucuccu uccgcgaccu cggauggcaa gacuggauca ucgcaccaga aggcuacgcc     1080

gccuacuacu gugaaggaga augcgccuuu ccucucaacu ccuacaugaa cgccaccaac     1140

cacgcaauug uacaaacccu aguucacuuc aucaacccag aaacaguccc aaaacccugc     1200

ugugccccca cacaacuaaa cgcaauaucc guccucuacu ucgacgauuc cucgaacguu     1260

auccucaaaa aauaccgcaa caugguaguc cgagccugcg gaugccacug aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  2162
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt8)

<400>  2162
gggagaaagc uuaccaugaa agccucagcc gcccuccucu gccuccuccu cacagcagcc       60

gccuucuccc cccaaggccu cgcccaacca gucggcauca acaccuccac aaccugcugc      120

uaccgcuuca uaaacaaaaa aauacccaaa caacgccuag aauccuaccg cagaaccaca      180

uccucacacu gcccccgcga agccgucauc uucaaaacca aacuagacaa agaaaucugc      240

gccgacccca cccaaaaaug gguccaagac uucaugaaac accuagacaa aaaaacacaa      300

acccccaaac ucuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  2163
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt8)

<400>  2163
gggagaaagc uuaccaugcu guuaacgcua aucauccuac uaccagucgu aagcaaguuc       60

ucuuuugucu cccugagcgc gccccagcau ugguccugcc cagaaggcac ccucgcaggc      120

aauggaaaca gcacaugcgu aggcccggcu ccauuccuaa ucuucagcca uggcaacagc      180

aucuuuagaa ucgacaccga gggcaccaac uacgaacaac ucgugguaga ugccggagug      240

agcguaauaa uggacuucca cuacaacgaa aaacgcauau auugggucga ccuagaacgg      300

cagcuccucc aaaggguauu ucucaacgga ucccgacagg agcgggugug caauaucgag      360

aaaaacgucu ccggaauggc aaucaacugg aucaacgaag aagucaucug gagcaaucag      420

caggaaggaa ucauaacagu cacugauaug aagggcaaua acucccacau acuacucuca      480

gcacuaaaau accccgccaa cguagcagua gauccugugg aacgcuucau cuucuggagc      540

ucagagguag ccgguagccu cuacagagcg gaucuugacg gagugggugu gaaagcacuu      600

uuagaaacaa gcgagaaaau aaccgcagua ucccuugacg ugcucgacaa acgacuauuu      660

uggauucagu acaaucggga aggcucgaac ucccuaauau gcucgugcga uuacgacggc      720

ggaagcguac acauaagcaa gcaccccacg cagcacaacc ucuuugcaau gucccuguuc      780

ggugaccgaa ucuucuacuc caccuggaaa augaagacca uauggaucgc gaacaaacau      840

acagggaaag auauggucag aaucaaccua cacagcuccu ucgucccccu aggagaacua      900

aaggucguac auccacucgc ccaacccaaa gcggaagacg acaccuggga accggaacaa      960

aaauugugca aauuaagaaa ggguaauugc uccagcacug ucugcgggca agaccuccaa     1020

ucacaccucu gcaugugcgc ggaaggguau gcccugagcc gggaccgcaa auauugcgaa     1080

gacgucaaug aaugcgccuu cuggaaccac ggauguacgc uugguugcaa aaacacaccc     1140

gggagcuacu acuguaccug ccccguaggc uucguccuac ugccggacgg caagcggugu     1200

caucagcuag ucaguugccc acgcaacguu ucagaaugca gccacgacug cguccuaaca     1260

uccgagggac cacucuguuu cugcccagaa ggcucagugc uagaaagaga cggaaaaaca     1320

ugcagcgggu gcucaagccc agauaauggc gggugcucgc aacuaugugu gccacuaucc     1380

ccugucuccu gggaaugcga cugcuucccc ggauacgauc uccaacucga cgaaaaguca     1440

ugcgccgcca guggccccca acccuuucuu cuauucgcca acagccaaga cauucgccac     1500

augcacuucg acggaacaga cuacggaacc cucuuaucuc aacagauggg caugguuuac     1560

gccuuagauc acgacccugu ggaaaacaaa auauacuucg cccacacagc acuaaaaugg     1620

aucgaaagag caaauaugga cggcucacaa cgagaacgcc ucauagaaga gggcguagac     1680

guacccgaag gccuagcggu ugacuggaua ggcagaaggu ucuacuggac ugaccgaggc     1740

aagucucuga uagggcgcuc ggaccugaac ggcaaacgcu ccaaaaucau aacaaaggag     1800

aacaucuccc aacccagagg aaucgcaguu cacccaaugg ccaaacgacu guucuggacc     1860

gacacuggaa ucaacccgcg gaucgaaucu uccagucuac aggggcuggg gcgucucguu     1920

auugcaucga gcgaccugau auggcccagc ggcauaacga uagacuuccu gacagacaaa     1980

cuguacuggu gcgacgcaaa acaaagcgug aucgaaaugg ccaaucucga cggaucaaaa     2040

agacgcagac ucacacagaa cgacgugggc cacccuuucg cuguagccgu auucgaagac     2100

uacgucuggu ucucagacug ggccaugccc agcguaaugc gaguuaacaa acgcaccggu     2160

aaagacagag uccgucucca aggcucaaug cuaaagccua guucccuugu aguaguacau     2220

ccacuagcua aacccggugc agacccgugc cuauaccaga acgguggaug ugaacacauu     2280

ugcaaaaagc gauugggaac cgccuggugc agcuguagag aaggauucau gaaagcgagu     2340

gacggaaaaa caugccucgc acucgacggc caccagcucc uagccggagg ggaaguagau     2400

cucaaaaacc aagugacgcc cuuagacaua cuaagcaaaa ccagaguauc ggaggacaac     2460

aucacggaga gccaacacau gcuuguagcu gaaaucaugg uaagcgacca agacgauugc     2520

gcgccagucg gaugcagcau guacgcacgg ugcaucuccg aaggugaaga ugcuaccugc     2580

cagugccuaa aaggauuugc gggagacggc aaacuaugua gcgauaucga cgaaugcgaa     2640

augggagucc cugucugucc gccagcaagc uccaaaugca ucaacaccga gggagguuac     2700

guaugccgau gcuccgaggg auaucaagga gacggcauac acugccucga cauagacgaa     2760

ugccaacugg gagagcacuc cugcggcgaa aacgcaagcu guaccaacac agagggcggc     2820

uacacaugca ugugcgccgg ccgccuaucu gaacccggac ucaucugccc cgacucgacc     2880

ccuccuccgc accuacguga ggacgaccac cauuacagcg ugcgaaauuc cgacucggag     2940

ugcccccuau cccacgacgg auacugccuu caugacggcg ucugcaugua uaucgaagcc     3000

cuagacaaau acgcguguaa uugcguuguc ggcuacaucg gggaacgaug ccaguaccgc     3060

gaccuaaaau ggugggaacu aaggcacgcc gggcauggcc agcagcagaa agucauaguc     3120

guggcagucu gcguaguggu gcucgucaug cuacuccuac uaucacucug gggagcgcac     3180

uacuaccgca cccaaaaacu ucuaagcaaa aaucccaaaa acccauacga ggaaucaagc     3240

cgggauguuc gaucgaggcg accagcggac acagaagaug gcaugagcuc gugcccgcag     3300

cccugguucg uggugaucaa ggagcaucaa gaccugaaaa acgggggaca accaguagcc     3360

ggugaagacg gccaagcagc cgacgguagc augcagccaa ccucauggag acaagaacca     3420

caacucugcg guaugggcac agaacagggc ugcuggauuc ccgucucauc cgacaagggc     3480

agcugccccc aaguaaugga gcgauccuuc cacaugccaa gcuacggaac gcagacccua     3540

gaaggcgggg uagaaaagcc gcauucccug cugucugcca acccccugug gcaacagcgc     3600

gcacucgacc caccucacca gauggaacuc acacaaugag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  2164
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt8)

<400>  2164
gggagaaagc uuaccaugac cgccggccga cgaauggaaa ugcucugcgc cggccguguc       60

cccgcacuuc uccucugccu cggauuccac cuacuccaag ccguccucuc caccaccguc      120

auccccucau gcauccccgg agaauccucc gacaacugca ccgcccuagu acaaacagaa      180

gacaaccccc gcgucgcaca aguuuccauc accaaaugcu ccucagacau gaauggcuac      240

ugccuccacg gacaaugcau auaccuaguc gacauguccc aaaacuacug ccgcugugaa      300

gucggauaca caggcguccg cugcgaacac uucuuccuca ccguccacca accccuaucc      360

aaagaauacg ucgcccucac cgucauccuc auaauccuau uccucaucac aguugucggc      420

uccaccuacu acuucugccg cugguaccgc aauagaaaau ccaaagaacc aaaaaaagaa      480

uacgaacgcg uaaccucagg cgaccccgaa cucccacaag ucuaaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  2165
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt8)

<400>  2165
gggagaaagc uuaccauggc agaaggcgaa auaaccacau ucaccgcccu caccgaaaaa       60

uucaaccucc ccccaggcaa cuacaaaaaa ccaaaacucc uauacugcuc caacggcgga      120

cacuuccucc gcauccuccc cgacggcaca gucgacggaa ccagagaccg cucagaccaa      180

cacauccaac uccaacucuc cgccgaauca gucggagaag uauacaucaa aagcaccgaa      240

accggacaau accuagccau ggacaccgac ggcuuacucu acggcucaca aacccccaac      300

gaagaaugcc ucuuccucga acgccucgaa gaaaaccacu acaacacaua caucuccaaa      360

aaacacgcag aaaaaaacug guucgucggc cucaaaaaaa acggcuccug caaacgcggc      420

ccccgcaccc acuacggcca aaaagccaua cucuuccucc cccuccccgu cucaucagac      480

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  2166
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt8)

<400>  2166
gggagaaagc uuaccauggu ggggguaggg ggaggggaug uggaggaugu aacgccgagg       60

ccagggggau gccaaauaag uggaagaggg gccaggggau guaacgggau cccgggagcg      120

gcagcguggg aggcagcgcu gccgagaagg agaccgagaa ggcacccgag ugugaacccg      180

aggagcaggg cggcagggag cccgagaaca agagggagaa ggacagagga aagaccaucg      240

gggagcaggu ugggggaucg agggcgagga agggcgcugc cgggagggag auugggaggg      300

agagggaggg ggagagcgcc agagagggug ggaggaaggg ggagaggaag agggacggcg      360

gcaccgaggg cggcgccggc ggcaagggga agcagaccag ggccggcggg aacgauggcg      420

gcggggagca uaacgacgcu accagcauug cccgaagacg gaggaucggg cgcauucccg      480

ccagggcauu uuaaagaucc gaagaggcug uacuguaaaa auggaggguu cuuucugaga      540

auacauccgg auggacgggu agauggagug agagagaaga gugacccgca cauaaaguug      600

caacugcaag cggaagagag aggaguagug agcauaaaag ggguaugugc caacagauau      660

cuagcaauga aggaagaugg aaggcuacug gcaagcaagu guguaacgga cgagugcuuu      720

uucuucgaaa ggcuagagag uaacaacuau aacacguaca gaagcaggaa auauacaagu      780

ugguaugugg cgcuaaagag gacgggacaa uacaagcugg ggagcaagac agggccgggg      840

caaaaggcaa uacuguuuuu accaaugagu gcgaagaguu aaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  2167
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt8)

<400>  2167
gggagaaagc uuaccaugca caaauggauc cuaaccugga uccuacccac ccuucucuac       60

cgauccugcu uccacaucau cugccuagua ggaaccaucu cacucgcaug caacgacaug      120

acacccgaac aaauggccac caacgucaac ugcuccuccc cagaacgcca cacacgcagc      180

uacgacuaca uggaaggcgg agacauccgc guccgccgcc ucuucugccg aacacaaugg      240

uaccuccgca ucgacaaacg cggcaaagua aaaggcacac aagaaaugaa aaacaacuac      300

aacaucaugg aaauacgcac aguagccguc ggaaucguag caaucaaagg cgucgaaucc      360

gaauucuacc ucgccaugaa caaagaaggc aaacuauacg ccaaaaaaga augcaacgaa      420

gacugcaacu ucaaagaacu cauccuagaa aaccacuaca acacauacgc aucagccaaa      480

uggacccaca acggaggcga aauguucguc gcccucaacc aaaaaggcau ccccgucaga      540

ggcaaaaaaa ccaaaaaaga acaaaaaaca gcacacuucc uccccauggc caucaccuga      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  2168
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt8)

<400>  2168
gggagaaagc uuaccaugaa acuacucccc uccgucgucc uuaaacucuu ccucgccgcc       60

guacucuccg cacucgucac aggcgaauca cucgaacgac uccgccgagg ccucgccgca      120

ggcaccucaa accccgaccc cccaaccgug uccacagacc aacuacuacc acucggcgga      180

ggacgcgacc gcaaaguccg cgaccuccaa gaagcagacc uagaccuccu ccgagucacc      240

cucuccucca aaccccaagc ccuagccacc cccaacaaag aagaacacgg caagcgaaaa      300

aaaaaaggca aaggccuagg caaaaaacgc gacccaugcc uacgcaaaua caaagacuuc      360

ugcauccacg gcgaaugcaa auacguaaaa gaacuccgag ccccaucaug caucugccac      420

cccggcuacc acggagaacg cugccacggc cuaucccuac ccgucgaaaa ccgccucuac      480

accuacgacc acacaacaau ccucgccguc gucgcagucg uccucucauc cguaugccuc      540

cucgucaucg ucggccuacu cauguuccgc uaccaccgac gaggcggcua cgacgucgaa      600

aacgaagaaa aagucaaacu cggaaugaca aacucccacu aaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  2169
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt8)

<400>  2169
gggagaaagc uuaccaugug ggucaccaag cuacuccccg cucuccugcu acaacacguc       60

cugcuccacc uccuacuccu ccccauagcc auaccauacg ccgaaggaca acgcaagcgc      120

cguaauacaa uacaugaguu caagaaaagc gccaaaacca cccuuaucaa aaucgacccc      180

gcccuaaaaa ucaagaccaa aaaggugaac accgccgacc aaugcgccaa cagaugcacc      240

agaaacaagg gccuccccuu cacaugcaaa gccuucguau ucgacaaggc ccgcaaacaa      300

ugccuauggu ucccauucaa cuccaugucc uccggcguca agaaagaguu cggccacgaa      360

uuugaccucu acgaaaauaa agacuacauc cgaaacugca ucaucggcaa aggacgcuca      420

uacaaaggca ccguauccau caccaaauca ggcauaaaau gccaacccug gagcucaaug      480

aucccccacg aacacucauu ucuaccaucc uccuaccgag gcaaagaccu ccaggaaaau      540

uacugcagga acccgcgcgg ggaagaaggc ggacccuggu gcuuuaccuc caaccccgaa      600

guacgguacg aagucugcga cauaccccaa ugcuccgaag uagaaugcau gacaugcaac      660

ggagaauccu aucggggccu cauggaucac acagaaucag guaaaaucug ccagcgcugg      720

gaccaccaga ccccucaccg ccauaaauuc cucccagaac gcuacccaga caaaggguuc      780

gacgacaacu acugcagaaa cccugacggc cagccacgcc caugguguua cacacuagac      840

ccccacaccc gaugggaaua cugcgccauc aaaacaugug cagacaauac aaugaaugac      900

accgacgucc cacucgaaac caccgaaugc auccaagggc agggagaagg auaccgaggc      960

acggucaaca ccaucuggaa cggcauaccc ugccaacggu gggacagcca auauccgcac     1020

gaacacgaca ugacuccaga aaacuucaaa ugcaaagacc ucagagagaa cuacugcaga     1080

aaucccgacg gauccgaauc acccuggugc uucaccacgg accccaacau ccgcguaggc     1140

uacugcucac aaauaccaaa cugcgauaug agccacgguc aagacugcua ucgcggcaac     1200

ggcaaaaacu acaugggaaa ccucucacag acccgcucag gccuaacgug uagcaugugg     1260

gacaaaaaca uggaggaccu ucaucggcac aucuucuggg aacccgacgc auccaaacuu     1320

aacgagaacu acugccgaaa cccagacgac gacgcccacg ggccauggug cuacacaggc     1380

aacccacuca ucccguggga cuauugcccc auaagccgcu gcgagggcga cacaacccca     1440

acaaucguga accuggacca cccugucauc ucgugcgcaa aaacaaaaca gcuucggguc     1500

gucaacggca ucccaacacg aacaaacaua ggguggaugg ucucucuacg cuacagaaac     1560

aaacacaucu gcggcggcuc acucaucaaa gaaagcuggg uccucacagc ucgccaaugc     1620

uucccaucaa gagaccucaa agauuacgaa gccuggcuag gcauacacga cguacaugga     1680

aggggagacg aaaaaugcaa acaaguacuu aacguaagcc aacucgucua uggcccagaa     1740

ggaagcgacc ucguccucau gaaacuagca cgcccagccg uccucgacga cuuuguaagc     1800

accauagacc uccccaacua uggcugcacc aucccagaga aaacgaguug cucagucuac     1860

ggcuggggau acacgggacu gaucaauuac gacggacuac uccgggucgc acaccucuac     1920

aucaugggca acgaaaaaug cucccaacac caccgcggca aaguaacucu caacgaaagc     1980

gaaaucugcg ccggagccga gaaaaucggc ucaggcccau gcgaaggcga cuacggcgga     2040

ccccuuguuu gcgaacaaca caaaaugagg augguacucg gcguaauagu ucccggcagg     2100

gggugcgcca ucccaaaccg acccggaaua uuugucagag uagcauacua cgcgaaaugg     2160

auucacaaaa ucauacuaac cuacaaaguc ccccagucgu aaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  2170
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt8)

<400>  2170
gggagaaagc uuaccauggc caaagccgcc gcaaucggca uagaccucgg uacgacguac       60

agcugcguag gcgucuucca acacggcaag guggaaauaa ucgcuaacga ccaaggcaac      120

agaaccacac cgucguacgu cgcauucacc gacaccgaac gacucaucgg ggacgcggcc      180

aaaaaccaag ucgcacuaaa cccccaaaac acaguguucg acgccaaacg acucaucggg      240

agaaaauucg gcgaccccgu aguccagucc gacaugaaac acuggcccuu ccaaguaauc      300

aacgacggag auaaacccaa aguacaaguc agcuacaaag gagagaccaa ggccuucuac      360

ccagaggaaa ucucaagcau ggugcugaca aaaaugaaag aaaucgcaga agccuaccua      420

ggauacccag ucacgaacgc cgucaucacc guccccgcau acuucaacga cagccaaaga      480

caggccacca aagacgccgg agucaucgca ggacucaaug uccuacgaau aauaaacgag      540

ccaaccgcag ccgccauagc auacggacuc gaccgaacag gcaaaggaga acgcaacguc      600

cuaaucuucg accucggggg cgggaccuuc gacgucucca uccuaacaau agaugacggc      660

aucuucgaag ugaaagccac cgccggcgac acacaccucg ggggagaaga cuucgacaac      720

cgccucguaa accacuucgu cgaagaauuu aagcgaaaac acaagaaaga caucagccaa      780

aauaagcgcg cggugcgacg ccugagaacc gcaugcgagc gagccaaacg aacgcucuca      840

uccucaaccc aagcgucacu cgaaaucgac ucacucuucg agggaaucga cuucuacacc      900

ucaaucacgc gagcccgcuu cgaagaauua ugcucagacc ucuuccgauc aacacuagaa      960

cccgucgaaa aagcccucag agaugcaaaa cuggacaaag cacaaaucca ugaccuuguc     1020

cuaguaggag gcucaaccag gauccccaaa guacaaaaac ugcuccaaga cuucuucaau     1080

gggcgagacc ucaacaaguc cauaaacccc gacgaagcag ucgcauacgg ggcagcaguc     1140

caagcagcaa uauuaauggg cgacaagucg gaaaacgucc aagaccuccu acuacuagac     1200

gucgcgccac uaagucuagg gcucgaaacc gcgggaggcg ucaugacugc ccuaaucaaa     1260

cgcaacucca ccauccccac aaaacaaacc caaauauuca ccacauacuc cgacaaccaa     1320

ccaggaguac ugauacaagu auacgaaggc gaacgagcca ugaccaaaga caacaaccua     1380

cuaggacgcu ucgaacucag cggaauccca cccgccccca gaggaguacc ccaaauagaa     1440

gucacauucg acaucgacgc aaacggcauc cuaaacguua cagcgaccga caaauccacc     1500

ggaaaagcaa acaagauaac gaucacaaac gacaaaggca gacucuccaa agaggagauc     1560

gagagaaugg uccaagaagc agagaaauac aaagcagaag acgaagucca acgugaacgc     1620

gucagcgcca agaacgcacu cgagucguac gccuucaaca ugaaaagcgc cgucgaggac     1680

gaaggacuca aggggaaaau cucagaagcc gacaaaaaga aaguacucga caaaugccaa     1740

gaaguaauca gcuggcuaga ugccaacaca cucgccgaaa aagacgaguu cgaacacaaa     1800

cgcaaagaau uagaacaagu cuguaacccc aucaucuccg gacucuacca aggcgcaggc     1860

ggaccaggcc ccggcggcuu uggcgcacaa ggccccaaag gcggcagcgg uuccggcccc     1920

acaauagaag aaguagacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2171
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt8)

<400>  2171
gggagaaagc uuaccauggc aaaagcggca gcaaucggaa ucgacuuagg caccaccuac       60

ucgugcgugg gagucuucca acacggcaag guggaaauca ucgcaaacga ccagggcaac      120

cgcaccaccc ccagcuacgu agccuucaca gacaccgaac gccugauagg agacgcagcg      180

aaaaaccagg ucgcacucaa cccacaaaac acagucuuug acgcaaaacg gcucauagga      240

agaaaauucg gcgacccggu gguccagagc gacaugaaac acuggcccuu ccaggugauu      300

aacgacggag acaagccgaa aguccaaguc ucguacaaag gcgaaaccaa ggcauucuac      360

ccggaagaaa ucuccuccau gguccuaacc aaaaugaaag aaauagccga agcauaccuc      420

ggcuaccccg ucaccaacgc gguaauaacc guccccgcau acuuuaacga cagucaacgu      480

caggccacca aagacgcagg ggucauagca gggcucaacg uccuccgaau caucaacgaa      540

cccaccgcag cagccauagc auacggucuc gaccgcacag gcaaaggcga acgaaacguc      600

cuaaucuucg accuaggugg gggcaccuuc gacgucucaa uccuaacaau agacgacggc      660

auauucgaag uaaaggcaac cgcaggcgac acccaccuag gcggcgaaga cuucgauaac      720

cggcucguga accacuucgu cgaagaguuc aaacgcaagc acaagaaaga cauaucgcaa      780

aacaaacgag caguaaggcg acuccgaacc gcgugcgaac gagcaaaaag aacccuaagc      840

ucgagcacgc aggccagccu cgaaauagac ucccucuucg aagggaucga cuucuacaca      900

ucaauaacac gagcacgauu cgaagaacuc ugcagcgauc uauuucgcuc aacccucgag      960

ccggucgaaa aagcccuccg cgacgcgaaa cuagacaaag cccagauaca cgaccuaguc     1020

cuaguagggg gaucaaccag gauaccaaaa guacaaaaac uacuccaaga cuucuucaac     1080

gggcgcgacc ugaacaaauc uaucaaccca gacgaagccg ucgcguacgg cgccgcuguc     1140

caagccgcaa uucugauggg agacaaaagu gaaaacguac aagaucuccu gcuacuagac     1200

guagccccac uaucacuggg auuagaaacc gcgggcggag ucaugaccgc ccuaauaaaa     1260

agaaacucaa caaucccaac gaaacaaaca caaaucuuca ccaccuacag cgacaaccaa     1320

cccggagugc ucauccaagu guacgaaggc gaacgcgcaa ugacaaaaga caacaaccuc     1380

cuaggaagau ucgaacuauc cggcauccca ccagccccac gcggaguccc acagauagaa     1440

gucacauuug acauagacgc gaacggaaua cuaaacguaa cagcgaccga caaaucgacg     1500

ggcaaggcaa auaaaauaac caucacgaau gacaaagggc gccuaagcaa ggaagagauc     1560

gaaagaaugg ugcaggaagc cgaaaaguac aaggccgagg acgaagucca aagagaacgg     1620

gucagcgcca aaaacgcacu agaaucguac gccuucaaca ugaaauccgc ggucgaagac     1680

gaaggacuca aaggaaaaau aagcgaagcu gacaaaaaga aaguacucga caaaugccaa     1740

gaaguaaucu ccuggcucga cgcaaacaca uuagccgaga aggacgaguu cgaacacaaa     1800

cgaaaagaac uugaacaagu augcaacccc auuauuucag gccuauacca aggagcagga     1860

gggcccgggc ccggaggcuu cggcgcgcaa ggcccaaaag gaggauccgg aagcggaccg     1920

acaaucgaag aagucgacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2172
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt8)

<400>  2172
gggagaaagc uuaccauggc aaccgccaag ggcaucgcca ucgggauaga ccucggaaca       60

accuacucau gcgucggagu cuuccaacac ggcaaagugg agauaaucgc caacgaccaa      120

ggaaaccgaa cgacacccuc auacguggcg uucacagaua cagagcgguu aaucggcgac      180

gcagccaaaa accaagucgc caugaaccca caaaacacgg ucuuugacgc caaaaggcua      240

auuggcagaa aauucaacga ccccguaguc caggccgaca ugaaacucug gcccuuccaa      300

gucauaaacg aaggcggcaa acccaaaguc cuagucucau acaaaggcga aaacaaagca      360

uucuacccgg aagaaaucuc gagcaugguc uuaacaaaau uaaaagaaac ggccgaagca      420

uuccuuggac accccgucac gaacgcagua aucacagucc ccgcauacuu caacgacucc      480

caacgccagg cgacaaaaga cgccgggguc auagccggcc uaaacguucu gaggauaauc      540

aacgagccga ccgccgcagc cauagcguac ggacuugaca aaggaggaca aggcgaacgc      600

cacguacuca ucuucgaccu gggcggcggc accuuugacg ucuccaucuu aaccaucgac      660

gacggcaucu ucgaaguaaa agccacggcc ggagacacac accuuggcgg agaagacuuc      720

gacaaccggc ucgucaguca cuuugucgaa gaguucaagc gcaaacacaa gaaagauauc      780

ucgcaaaaca aaagagcagu ccgaagacuc cgcaccgccu gcgaacgcgc caagagaaca      840

cucagcagcu caacacaggc aaaccuggaa aucgacucac ucuacgaagg cauagacuuc      900

uacaccucaa uaacacgagc gcgcuucgaa gaacuaugcg ccgaccucuu cagagggacc      960

cuggaaccgg ucgaaaaagc ccuccgagac gccaaaaugg acaaagcaaa aauccacgac     1020

auaguccuag uagguggguc aacccgaauc cccaaagugc aacgacuccu ccaagacuac     1080

uucaacgggc gcgaccucaa uaaaucaauc aaccccgacg aagcaguagc auacggcgca     1140

gcaguccaag cagcgauccu aaugggggac aagagcgaaa aaguccagga ucuccuccuc     1200

cuugacgucg caccucuauc ucuaggacua gaaaccgcag gggguguaau gacagcacuc     1260

aucaaaagaa acucaacaau acccaccaaa caaacacaaa ucuucacaac cuacuccgac     1320

aaccaaccag gaguacuaau acaagucuac gaaggggaac gcgccaugac caaagacaac     1380

aaccuccugg gccguuucga ccuaaccggu aucccaccag caccacgcgg aguaccgcaa     1440

auagaaguga cguucgacau agacgcaaac ggaauccuca acgucaccgc gaccgacaaa     1500

ucaaccggca aagugaacaa aaucaccauc acaaacgaca aagggcgauu aagcaaagaa     1560

gaaaucgaac gaaugguccu cgacgcagaa aaauauaagg ccgaagacga aguccaacga     1620

gagaaaauag ccgccaaaaa cgcauuagaa ucauacgccu ucaauaugaa aagcguagua     1680

ucagacgaag gccuaaaagg caaaaucagc gagagcgaca aaaacaagau acuagacaaa     1740

ugcaacgaac uccuaagcug gcucgaggua aaccaacucg cagaaaagga cgaguucgac     1800

cacaaaagaa aagaacuaga gcaaaugugu aacccaauca uaacaaaauu auaccaagga     1860

ggcugcacgg ggcccgccug cggaacaggc uaugucccag gaagacccgc caccggcccc     1920

acgauagaag aagucgacua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2173
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt8)

<400>  2173
gggagaaagc uuaccaugag cgcccgggga cccgcaaucg gcaucgaccu aggaaccaca       60

uacagcugcg uaggcguguu ccaacacgga aaagucgaga uaaucgccaa cgaccaagga      120

aaccgaacca ccccaucaua cguagcguuc accgacaccg aaagacucau cggggaugca      180

gcgaagaacc agguggcuau gaaccccaca aacacaaucu ucgacgccaa acgccuaaua      240

gggagaaaau ucgaagacgc aacaguccaa ucagacauga aacacuggcc cuucaggguc      300

gucucagaag gaggaaaacc caaaguacaa gucgaauaca aaggcgaaac aaaaacguuc      360

uucccagaag agaucucauc caugguccuc acaaagauga aggaaauagc cgaagccuac      420

cuaggcggca aaguccacag cgcagucaua accguaccag cauacuucaa cgacagccaa      480

cggcaagcca caaaagacgc aggaaccauc accggguuaa acguacuacg aauaauaaac      540

gaacccacag cagcagccau cgcguacggc cucgacaaga aaggcugcgc cggaggcgag      600

aaaaacguac ucaucuucga ccucggcgga ggcacauucg acguaucgau acucacaaua      660

gaagacggca uauucgaagu caaaucaacc gccggagaua cacaccuugg aggggaggac      720

uucgacaaca gaauggugag ccaccuagca gaggaguuca aacgaaaaca caagaaagac      780

auaggaccca acaaaagggc cguacgcaga cucagaacag caugcgaaag agccaaacga      840

acacuaucau ccuccacaca ggccagcaua gaaauagacu cacuauacga aggagucgac      900

uucuacacca gcaucacacg cgccagauuc gaagaacuca acgccgaccu auuccgaggc      960

acccucgagc cggucgagaa agcgcuccga gacgcaaaac ucgacaaagg acaaauacaa     1020

gaaauagucc ucgucggagg cuccacccga aucccuaaaa uacaaaaacu acuccaagac     1080

uucuucaacg gaaaagaacu aaacaaauca aucaaccccg augaagccgu ugcauacggc     1140

gccgcugucc aagcagcaau ccuaauagga gauaaaagcg aaaacguaca agaccuccug     1200

cuacuagacg ucaccccacu cucacucgga aucgagaccg ccggcggugu aaugacccca     1260

cucauaaaac gaaacaccac cauccccacc aaacaaacac agacguucac caccuacucc     1320

gacaaccaau cauccgugcu agugcaaguc uacgaaggcg aaagagccau gaccaaagac     1380

aacaaucucc ucggcaaauu cgaccugacg ggcauacccc cagccccacg aggcgucccc     1440

caaaucgagg ucaccuucga cauagacgcg aacggcaucc ucaacgucac ugcugcagac     1500

aaaucgacag gaaaggaaaa caaaaucacc aucacaaacg acaaggggcg ccucagcaaa     1560

gacgacaucg accgaauggu acaagaagca gaacgcuaca agagcgaaga cgaagccaac     1620

agagaccgcg ucgccgccaa aaacgcccuc gaauccuaca cauacaacau aaaacaaacc     1680

gucgaagacg aaaaacuacg cggaaaaaua agcgagcaag acaaaaacaa aauauuagac     1740

aaaugccaag aaguaaucaa cuggcucgac cgcaaccaaa uggccgaaaa agacgaauac     1800

gaacacaaac aaaaagaacu cgaacgagua ugcaacccga uaaucaguaa gcuguaucaa     1860

ggaggcccag gaggcggaag cggcggcgga gguucgggcg cguccggagg cccaacaaua     1920

gaagaagucg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  2174
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt8)

<400>  2174
gggagaaagc uuaccaugag cgugguaggc auagaccugg gcuuccagag cuguuauguc       60

gcaguagccc gcgcaggcgg cauagaaaca aucgcaaacg aguacagcga ccgcugcaca      120

ccggcaugca ucucguucgg acccaaaaac cguagcaucg gcgcggcagc gaaaagccag      180

gucauaagca augcgaaaaa cacaguccag ggauucaaac gcuuccacgg ccgagcauuc      240

uccgacccau ucgucgaagc agagaaaagc aaccuggcau acgacaucgu ccaguuaccg      300

accggccuaa ccgggaucaa agucaccuac auggaagagg aacgcaacuu caccacagaa      360

caagucaccg ccaugcugcu aagcaaacug aaagagacug cagaguccgu acucaagaaa      420

ccaguggugg acugugucgu aagcgugccg ugcuucuaca cggacgccga acgacguagc      480

gugauggacg caacacaaau agcgggacug aacugucucc gccuaaugaa ugaaacgaca      540

gcaguagccc ucgcuuacgg aauauacaaa caagaccuac ccgcgcucga agagaaaccc      600

cgcaacgucg ucuucgugga caugggacac ucggccuacc aagucuccgu cugcgccuuc      660

aaccggggca aacugaaagu ccucgccacc gcauucgaca ccacacuugg aggccgaaaa      720

uucgacgaag uucucgucaa ccacuucugc gaagaguucg ggaagaaaua caaacuugac      780

auaaaaucca aaauccgagc acugcuccga cucagucaag aaugcgaaaa acuaaagaag      840

cucauguccg cgaacgccag cgaccucccc cuauccaucg aaugcuuuau gaacgacguc      900

gacgucuccg gaaccaugaa ccgagggaaa uuccuagaaa ugugcaacga cuuacuagcg      960

agaguagaac caccccuacg aagcguacua gaacagacca aauuaaagaa agaagauauc     1020

uacgcaguag aaauaguggg cggagcaacc cgcauacccg ccguaaaaga gaaaaucuca     1080

aaauucuuug gcaaagaacu cucgacaaca cuaaacgccg acgaagcagu gacccgcggg     1140

ugcgccuugc aaugcgcaau ucucagcccc gcuuucaaag uaagagaauu uucaauaaca     1200

gacgucguac cauaccccau aucacuccgc uggaacuccc cagcagaaga aggaagcucc     1260

gacugcgaag ucuucuccaa aaaccacgca gcccccuucu cuaaaguccu caccuucuac     1320

cggaaagaac ccuucacccu agaagccuac uacucgucac cacaggaccu accauauccc     1380

gaccccgcaa ucgcgcaauu cuccguccaa aaaguaacac cccagagcga cgggagcagc     1440

agcaaaguua aaguaaaagu acguguaaac guacacggaa ucuucucagu cuccucagcc     1500

ucccucgucg aaguccacaa aagcgaagaa aacgaagaac caauggaaac cgaccagaau     1560

gcaaaagaag aagagaaaau gcaagucgac caagaagaac cccacgucga ggagcaacaa     1620

caacaaacuc cagccgaaaa caaggccgaa ucagaagaaa uggagaccuc acaagccggg     1680

ucaaaagaca agaaaaugga ucaaccgccc caagcgaaga aagcgaaagu caaaacaucc     1740

acagucgacc uccccauaga gaaccaacug cucuggcaaa ucgaccgcga gaugcucaac     1800

cucuacaucg agaacgaagg aaaaaugauc augcaggaca aacuagaaaa agaaaggaac     1860

gacgccaaaa acgccgugga agaguacguc uaugaaaugc gcgacaaauu aagcggagag     1920

uacgagaaau uugucuccga agacgacaga aacuccuuca cacuuaaacu cgaagacacc     1980

gaaaacuggc uauacgaaga cggcgaggac cagcccaaac aaguauacgu ggacaaacuc     2040

gcagagcuga aaaaccuagg acaacccauc aaaauccgau uucaagaaag cgaagaacgc     2100

cccaagcugu ucgaggaacu cggaaaacaa auccaacaau acaugaaaau cauaucaucc     2160

uucaaaaaca aagaggacca auacgaccac cucgacgccg cagauaugac gaaaguagaa     2220

aaguccacca acgaagcgau ggaauggaug aacaacaaac ucaaccuaca aaacaaacaa     2280

ucgcucacaa uggaucccgu gguaaagagc aaggagaucg aggcaaaaau uaaagaacuc     2340

acauccacau gcagccccau aaucucaaaa cccaaaccaa aggucgaacc gccaaaagaa     2400

gaacagaaga acgccgagca aaacggccca guagacggcc aaggcgacaa cccaggcccc     2460

caagcagcgg aacagggaac cgacacggcc guccccucag auucggacaa gaaacuccca     2520

gaaauggaca ucgacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  2175
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt8)

<400>  2175
gggagaaagc uuaccauguc aguggucggc aucgaccuag gcuuccucaa cugcuacauc       60

gccgucgccc gcuccggcgg gauugaaaca aucgcaaacg aguacucgga caggugcaca      120

cccgcuugca uaucacuggg aucgcggacg cgcgccauag gaaacgcagc caaaagccag      180

aucguaacaa acgugcgcaa caccauccau ggcuuuaaaa agcuccacgg caggagcuuc      240

gacgacccca ucguucaaac cgagcgcauc agacuaccau acgaauuaca gaaaaugccc      300

aacggcagcg ccgggguaaa aguccgcuac cucgaagaag aacgaccuuu cgcgaucgaa      360

caaguuaccg gaauguuacu agcaaaacug aaggaaaccu cagagaacgc ccucaagaaa      420

cccguggcag acugcguaau aucaaucccu agcuucuuca cagacgcaga aagacguuca      480

guaauggcgg cagcccaagu agcagggcuc aacugccucc gacuaaugaa cgaaacaaca      540

gccguggccc ucgccuacgg cauauacaaa caagaccugc cgccacuaga cgaaaagccc      600

cgcaacgucg uguucauaga caugggacac agcgccuacc aaguccucgu cugcgccuuu      660

aacaagggca aacucaaagu ccucgccacg acauucgacc ccuaccuggg cggacgcaau      720

uucgacgaag cucucguaga cuacuucugc gacgaguuca aaacaaaaua caaaaucaac      780

gucaaggaaa acucaagagc ccugcuccga cuauaucaag aaugcgagaa acuaaagaaa      840

cucauguccg cgaacgccag cgaccuccca cuaaacaucg aauguuuuau gaacgaccug      900

gacgucagcu ccaaaaugaa ccgcgcccag uucgaacaac ucugcgccag ccuacuagca      960

cgcguggagc caccccucaa agccguaaug gaacaagcga accuccagcg cgaggacaua     1020

ucaagcaucg agauaguagg cggcgcgacg cgcauccccg ccguaaaaga gcaaaucaca     1080

aaauucuucc ucaaagacau uucaacaaca cuuaaugcag acgaagcagu agccagggga     1140

ugcgcucuac aaugcgccau ccucagcccg gcauucaaag uacgcgaguu cuccaucaca     1200

gaccuagucc ccuacucaau cacacucaga uggaaaaccu cauucgaaga cgggagcgga     1260

gaaugcgaag uauucugcaa aaaccacccu gccccauuca gcaaagugau aacguuccac     1320

aagaaagaac ccuucgaacu ugaagcguuc uacacaaacc uucacgaagu ccccuacccu     1380

gaugcgcgaa ucgguucauu cacaauacag aacguauucc cccaaagcga cggcgacucg     1440

agcaaaguaa aagucaaagu ccgcguaaac auccacggca ucuucucagu agcaagugcc     1500

agcgugaucg aaaaacaaaa ccucgaaggc gaccacagcg acgcccccau ggagacagaa     1560

acaucguuca aaaacgaaaa caaagacaac auggacaaaa ugcagguaga ccaagaagaa     1620

ggccaccaga agugccacgc cgaacacaca cccgaagaag aaaucgacca caccggcgcc     1680

aaaacaaaau cggcagucuc cgacaaacaa gaccggcuaa accaaacccu caagaaaggc     1740

aaaguaaaau caaucgaccu acccauacag uccucacucu gccgccaacu gggccaagau     1800

cuccuaaacu cauacaucga aaacgaagga aaaaugauaa ugcaagacaa acucgaaaaa     1860

gaacggaacg acgccaaaaa cgcgguagag gaguacgucu acgacuuucg ggaccgacug     1920

ggcacgguuu acgaaaaauu caucacaccc gaagaccuaa gcaagcuauc ugcgguccug     1980

gaagauaccg agaacuggcu cuacgaagac ggcgaagacc aaccaaaaca aguguacgua     2040

gacaagcugc aggaacugaa gaaauauggg caaccaaucc aaaugaaaua cauggaacac     2100

gaagaaaggc ccaaagcacu gaacgaccua ggcaagaaaa uucaauuagu caugaaagug     2160

aucgaagcgu acagaaacaa agacgaaaga uacgaccacc ucgacccuac agagauggag     2220

aaaguagaga agugcauauc agacgccaug uccuggcuaa acagcaagau gaacgcccaa     2280

aacaaacuca gccuuacgca agaccccgug gucaaagucu cagaaauagu ugcgaaauca     2340

aaggagcuag auaacuucug caaccccaua auauacaaac cgaagcccaa agccgaaguc     2400

cccgaagaca agcccaaagc caacagugaa cauaacgggc cgauggacgg acagucaggc     2460

acugagacca aaagcgacuc gacaaaagac agcagucaac acacaaaguc guccggagag     2520

auggaagucg acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  2176
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt8)

<400>  2176
gggagaaagc uuaccaugaa acucagccua gucgcagcca ugcugcugcu ccucagcgca       60

gcacgggcag aagaggaaga caagaaagaa gacgugggaa caguaguagg cauagaccuc      120

ggaacgacau acagcugcgu agggguauuc aaaaacggac gagucgagau cauagccaac      180

gaccagggca acagaauaac cccaaguuac guagcguuca cacccgaggg ugaacgacug      240

aucggagacg cagcgaaaaa ccaacucaca agcaaccccg aaaacacagu auucgacgca      300

aagcgacuaa uaggccgcac cuggaacgac cccucggucc agcaagacau caaauuccug      360

ccauucaaag ucgucgagaa gaaaacaaaa cccuacauac aaguagacau agggggcggg      420

cagacgaaaa cguucgcgcc agaagaaaua agcgcaaugg uacugacgaa aaugaaagag      480

accgcagaag cguaccuggg caagaaaguc acccacgcag ucguaacagu gccagccuac      540

uucaaugacg cgcaacgaca agcaacaaag gacgcaggaa caaucgcggg acugaacgug      600

augcgaauca uaaaugaacc caccgccgcc gcaauagcgu acggacuaga caaacgggaa      660

ggcgagaaaa acauccuagu cuucgaccug ggcggaggua ccuucgacgu aagucuccug      720

acaaucgaca acggcguauu cgaagucgua gcaacaaacg gggacacaca ccugggagga      780

gaagacuucg accagcgagu aauggagcac uucauaaaac uauacaagaa gaaaaccgga      840

aaagacguaa ggaaagacaa cagagccgua caaaaacuca ggcgggaggu cgaaaaagcc      900

aaacgcgccc uauccagcca acaccaagcg cgcaucgaaa uagaaucauu cuacgagggg      960

gaagacuuca gcgaaacccu aacacgcgca aaauucgaag aacugaacau ggaccuauuc     1020

cgcagcacga ugaaaccagu acaaaaaguc cuagaggaca gcgaccuaaa gaaaagcgac     1080

auagacgaaa uaguauuagu gggcggcucg accaggauac caaaaauaca acaacuggua     1140

aaagaguucu ucaacggcaa agaaccaucg cgagggauca acccagacga agccgucgca     1200

uacggagccg caguucaagc aggaguacug agcggcgacc aagacacagg agaccucgua     1260

cuacuggacg ugugcccacu cacccuaggc auagaaacag uaggcggggu aaugacaaaa     1320

cucauaccaa gaaacacggu cgugcccacc aagaaaagcc agauauucag cacggcaagc     1380

gacaaccaac ccaccguaac gaucaaaguc uaugaaggag aacgaccccu cacaaaagau     1440

aaccaccuac ugggcaccuu cgaucuaaca ggcauaccac cagccccaag agggguacca     1500

caaauagaag ugacauuuga aaucgacgua aacgggauuc uccgagugac cgcggaagac     1560

aaaggaaccg gaaacaaaaa caaaauaacg auaaccaacg accaaaacag acucacaccg     1620

gaagaaaucg aaagaauggu caacgacgca gagaaauuug ccgaagagga caagaaauug     1680

aaagagcgaa uagacaccag aaacgaacuc gaaagcuacg ccuacucacu caaaaaccag     1740

auaggugaca aagaaaaacu aggagggaaa cuaagcagug aagacaaaga aaccauggaa     1800

aaagccgucg aagagaaaau cgaauggcua gaaucacacc aagacgcaga cauagaagac     1860

uucaaagcca aaaagaaaga acuagaagaa auaguacaac caaucauauc caaacuauac     1920

ggaagcgcag ggcccccacc cacaggagaa gaggacacag cggaaaaaga cgaacuauaa     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  2177
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt8)

<400>  2177
gggagaaagc uuaccaugca agcaccccgg gagcucgcag ucggcauuga ucucggaaca       60

acauacuccu gcguaggagu guuccagcaa gggcgcgugg aaauacucgc aaacgaccaa      120

ggcaaccgga ccaccccaag cuacguggcc uucaccgaca cagagcggcu gguaggagac      180

gcagcaaaaa gccaagccgc gcugaauccc cacaacacag ucuucgacgc aaaaaggcua      240

auuggaagaa aauucgcaga cacaacagua caaagcgaca ugaaacauug gcccuuccga      300

gucgucucag aagggggcaa acccaagguc agagucugcu acagagguga agacaaaaca      360

uucuaccccg aagagauauc aagcauggug cucagcaaaa ugaaagagac ggccgaggca      420

uaccucgggc aaccggucaa acacgcggua auaacagucc cagcauacuu caacgauagc      480

caacgccaag ccacaaaaga cgccggagca aucgccgggc ucaacguccu acgaauaauc      540

aacgaaccaa cagcggcagc aaucgcuuac gggcuagaca gaagaggcgc aggcgaacgg      600

aacguccuga uauucgaccu aggaggagga acauucgacg uaucagugcu aagcaucgac      660

gcaggaguau ucgaagucaa agccacggca ggagacacac accugggcgg ggaagacuuc      720

gacaacaggc uaguaaacca cuucauggaa gaguuccggc gcaaacacgg gaaagaccua      780

ucagggaaca aaagagcccu gcgaaggcug agaacagccu gcgaacgcgc aaaaaggaca      840

cuaagcagcu ccacacaagc aacacuagaa auagacuccc ucuucgaagg agucgacuuc      900

uauaccucga ucacgcgcgc acgauucgaa gaacuaugca gcgaccucuu ccgaucgacc      960

cuggaaccgg uagaaaaagc ccuaagagac gcgaagcuag acaaggccca aauacacgac     1020

guaguccucg uaggaggauc gacacgcauc ccaaaaguac aaaaacuccu acaagacuuc     1080

uucaacggga aagaacucaa caagucaaua aaccccgacg aagcaguggc cuacggugcc     1140

gcaguucagg ccgcaguccu gaugggcgac aagugcgaaa agguucaaga ccuacuacuc     1200

cuagacgugg caccccucuc ccucggacua gagacagcgg gcggagucau gacuacacua     1260

auccaaagaa acgcaaccau cccaacaaag caaacacaaa cauucacaac cuacucagac     1320

aaccaaccag gcguauucau ccaagucuac gagggcgaac gcgcaaugac caaagauaac     1380

aaccuacugg gccgauucga gcucucaggc auacccccag caccccgagg agucccacaa     1440

auagaaguua cauucgacau cgacgccaac gggauauuga gcgugaccgc aacagaccgc     1500

ucaaccggaa aggcaaacaa aauaacaaua acaaacgaua aaggacgacu aagcaaagaa     1560

gaaguggagc gcaugguaca cgaggcggaa caauacaagg ccgaggacga agcccaacgg     1620

gacagaguag ccgccaaaaa cagccuggaa gcgcacgucu uccacgucaa aggaucacua     1680

caggaagaau cccuccgaga caaaauaccc gaggaagaca gacgaaaaau gcaagacaag     1740

ugccgagaag uccuagccug gcucgaacac aaccaacugg ccgaaaaaga agaauacgaa     1800

caccaaaagc gagaacuaga gcaaauaugc agaccaauau ucucgagacu auacggcggg     1860

ccgggcguac cuggcggauc gagcugcggc acccaagccc gacaaggcga cccaucaacc     1920

gggccuauaa ucgaggaagu ggacuaagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  2178
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt8)

<400>  2178
gggagaaagc uuaccaugca agcaccacgc gaacucgcag ucggaaucga ccuaggcacc       60

acauacucau gcgucggcgu auuccaacaa ggaagagucg aaauccucgc caacgaccaa      120

ggaaaccgaa ccacgccaag cuacgucgca uucacagaca cagaacgccu ggucggcgac      180

gcagccaaaa gccaagccgc acucaaccca cacaacacag uauucgacgc aaaacggcuc      240

auaggccgca aauucgccga caccaccguc caaagcgaca ugaaacauug gccauuccaa      300

gucguaagcg aaggcggcaa acccaaaguc cgagucugcu acagaggcga ggacaaaaca      360

uucuacccag aagaaaucuc cagcauggua cuaaguaaaa ugaaagaaac cgcagaagca      420

uaccuaggcc aacccguaaa acacgcagua auaaccguac caaccuacuu cucaaacagc      480

caacgccaag caacaaaaga cgcaggagcc aucgccggcc ucaaaguccu cccaauaaua      540

aacgaagcaa ccgcagccgc aaucgccuac ggacucgacc gacgaggcgc cggcaaacga      600

aacguacuca uauucgaccu cggcggcggc accuucgacg uaagcguacu aagcaucgac      660

gcaggagucu ucgaagucaa agcaacggcc ggcgacacac accuuggagg agaagacuuc      720

gacaacaggu uagucaacca cuucauggaa gaguuccgcc gcaaacacgg aaaagaccuc      780

ucaggaaaca aacgcgcacu gcgacggcua cgaacagcgu gcgaacgcgc aaaacgcacc      840

cccuccagca gcacacaagc cacucucgaa aucgacucac uguucgaagg cgucgacuuc      900

uacaaaucca uaacacgcgc acgcuucgaa gaacucugca gcgaccucuu ccgcagcacc      960

cucgaacccg uugaaaaagc ccuacgcgac gccaaacuag acaaagccca aauccacgac     1020

uucguccugg gcggcggccu ccacucacac ccccaaggag ccgaaguagc agcaggacuc     1080

cugcaacgcc aaggagcaga acaagaacac caacccuagg gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  2179
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt8)

<400>  2179
gggagaaagc uuaccaugag caaaggacca gcaguaggga uagaccucgg aaccacauac       60

uccugcguag ggguauucca gcacggcaaa guagaaauaa uagcgaacga ccaaggcaac      120

cggaccaccc cuuccuacgu agccuucacc gacacagagc gccucaucgg agacgcggcc      180

aaaaaccaag ucgcaaugaa ccccaccaac acaguauucg acgcaaaaag acucauaggc      240

aggcgguucg acgacgcagu cguacaaagc gacaugaagc acuggcccuu cauggucgua      300

aacgacgcag gacgcccaaa aguccaagua gaauacaagg gcgagacaaa auccuucuac      360

ccagaagagg ucuccagcau gguacugacc aaaaugaaag agauagcaga agccuaccuc      420

ggaaaaacug uaaccaacgc aguagucaca gucccagccu acuucaauga cagccaacgc      480

caggccacca aagacgccgg aaccaucgcc ggacuuaacg uacuacgcau caucaaugag      540

ccaacggcgg ccgcaaucgc guacgggcuc gacaaaaagg uaggagccga aagaaacguc      600

cugaucuucg accuaggagg aggaacauuc gacgucucaa uccucacaau agaagacggc      660

auauucgaag uaaagagcac ggccggcgac acacaccugg gaggagaaga cuuugacaac      720

agaaugguaa accacuucau agcagaguuc aagcgcaagc acaagaagga caucagcgaa      780

aacaaaagag caguacgccg ccuccgcacc gccugugaaa gagcaaaacg cacccucagc      840

uccagcaccc aagcaaguau agaaauugac ucacuauacg aaggcaucga cuucuacacc      900

agcaucaccc gagcaagauu cgaagaauua aacgcagacc ucuucagagg aacccuggac      960

ccagucgaga aagcacuacg agacgcaaaa cuagacaaaa gucaaauaca cgacauaguc     1020

cuagucggag gcagcacacg aaucccgaag auacagaaac uccuccaaga cuucuucaac     1080

ggaaaagaac uaaacaaaag cauaaaucca gacgaagcag ucgcauacgg cgcagcgguc     1140

caagcggcca uacuuucagg cgacaaaagc gagaacguac aagaccugcu gcuccuggac     1200

gucacgccgc ucucacuagg caucgaaaca gccggcggcg uaaugaccgu gcucauaaaa     1260

cgcaacacaa ccauaccaac aaaacagacc cagaccuuca cgacauacuc cgacaaccag     1320

ccaggcguac ucauacaggu cuacgaagga gaacgcgcaa ugacaaaaga caacaaccuc     1380

cuaggcaaau ucgaacucac agggauaccc ccagcaccgc gcggaguccc acaaauagaa     1440

gucaccuucg acaucgacgc aaacggaauc cuaaacguau ccgccguaga caaaucaacc     1500

ggaaaagaaa acaaaauaac gaucacaaac gacaaaggcc gccuaagcaa ggaggacauc     1560

gagagaaugg uccaggaggc cgaaaaauac aaagccgaag acgaaaaaca acgcgacaaa     1620

guaaguagca agaacagccu ggaaagcuac gcauucaaca ugaaggcgac ggucgaagac     1680

gaaaaacugc agggaaaaau aaacgacgaa gacaaacaga aaauccuaga caaaugcaac     1740

gaaaucauaa acuggcugga caaaaaucaa accgccgaaa aagaagaauu ugaacaccaa     1800

caaaaggagc ucgaaaaagu gugcaauccc auaaucacca aacuauacca aucagcggga     1860

ggaaugcccg gagggaugcc gggcggguuc ccaggagggg gagcaccccc aagcggaggc     1920

gcaagcucgg gccccacgau agaggagguc gacuaaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  2180
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt8)

<400>  2180
gggagaaagc uuaccaugau aucagccagc cgcgcggccg ccgcaagacu ggugggagca       60

gccgcgagcc gcggaccaac agcagcgcgg caccaagaca gcuggaacgg acugucacac      120

gaagcauucc gacucgugag uagaagagac uacgcgagcg aagccauaaa aggggccgua      180

gucggaaucg accucggaac aacaaauagu ugcguagccg ugauggaggg aaaacaagcc      240

aaaguacuag agaacgcgga gggagcgaga accacaccaa gcgucguagc cuucaccgca      300

gauggagaaa ggcucguagg caugcccgca aaaagacaag cagugacgaa cccaaacaac      360

accuucuacg cgacaaagcg ccucaucggc cgacgcuacg acgaccccga ggugcaaaaa      420

gacaucaaaa acguaccauu caaaauagug agagcaagca acggcgacgc cugggucgaa      480

gcccacggca aacuauauag ccccagccag auaggggccu ucgucuugau gaaaaugaaa      540

gagaccgcag aaaacuaccu aggacacaca gccaagaacg caguaauaac cguaccugca      600

uacuucaacg acagccagag acaagccaca aaggacgccg gccagauaag cggacuuaau      660

guacuacgcg uaauaaacga accgacagcc gccgcgcucg cauacggccu agacaaaagc      720

gaggacaaag uaauagcagu auacgaccua ggagggggaa cuuucgacau cucgauacua      780

gaaauacaaa agggaguuuu cgaggucaag ucaacaaacg gggacaccuu cuuaggcgga      840

gaagacuucg accaagcgcu gcuacgccac aucgugaaag aguucaaaag agaaacaggg      900

gucgaccuca cgaaagacaa cauggcacuc caaagaguca gagaagcggc agaaaaagcg      960

aaaugcgaac uaagcagcag cguccaaaca gacauaaacc uacccuaccu aacaauggau     1020

agcucaggcc caaaacaccu gaacaugaag cucacgcgcg cgcaauucga ggggauagug     1080

acugaccuca ucagaagaac cauagcacca ugccaaaaag caaugcaaga ugccgaagua     1140

agcaaaagcg acauagggga agucauccua gucggaggaa ugacgaggau gccaaaagua     1200

caacaaacag uacaagaccu cuucgggaga gccccgucca aggccguaaa cccggacgag     1260

gcaguagcca uaggagcggc cauacaagga ggaguccuag ccggggacgu aacagacgug     1320

cugcugcucg acguaacacc ccugucucug ggcauugaaa cccuaggagg cguuuucaca     1380

aaacucauca acagaaacac gacgauaccg acuaagaaau cccaagucuu cuccacagcc     1440

gccgacgguc aaacccaagu agaaaucaaa gucugccaag gagagaggga aauggccggg     1500

gacaacaaau uacucgggca auucacccuc aucggaaucc cacccgcgcc ccgaggcgug     1560

ccccagauag aggucacauu cgacaucgac gccaacggaa uaguacacgu aagcgccaaa     1620

gacaaaggaa caggccggga acaacagaua gucauacagu caagcggagg ccucagcaag     1680

gacgacaucg aaaacauggu caaaaacgca gagaaguacg cagaagagga ccggagaaag     1740

aaagaacgcg uggaagcagu aaacauggcc gaagggauaa uacacgacac cgagacaaaa     1800

auggaggagu ucaaagacca gcugcccgcg gaugaaugua auaaacuaaa agaagaaaua     1860

agcaaaauga gggaacuacu cgcacgaaag gacucugaaa cgggcgagaa cauuagacaa     1920

gcggcaagca gccuccaaca agcaucccug aagcucuuug aaauggcaua caagaaaaug     1980

gcgucggaaa gggaaggguc cgggagcuca ggcacgggag agcaaaagga agaccaaaag     2040

gaggaaaaac aauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  2181
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt8)

<400>  2181
gggagaaagc uuaccauggc ggacaaagaa gccggaggaa gcgacggccc ccgcgaaacc       60

gccccaacau ccgccuacag cucgcccgcc cgcagccuag gagacaccgg aaucacaccc      120

cucucucccu cccacauugu caacgacacc gacuccaacg uaucugaaca acaaucauuc      180

cucguaguag ucgcaguaga cuucggcacc accucguccg gauacgcaua cucguucacc      240

aaagaacccg aauguaucca cguaaugaga cgcugggaag gcggcgaccc cggggucucc      300

aaccagaaaa ccccaaccac cauacuacuc accccagaaa gaaaauucca cuccuucgga      360

uacgccgccc gcgacuucua ccacgaccuc gaccccaacg aagccaagca auggcucuac      420

uuggaaaaau ucaaaaugaa acuccauaca accggagacc ucaccaugga caccgaccuc      480

acagcugcaa acggcaagaa agucaaagca cucgagaucu uugccuacgc gcugcaauac      540

uucaaagaac aagcccucaa agaacucucc gaccaagcag ggucagaguu cgaaaauagc      600

gacguccgau gggucaucac cgucccagca auuuggaaac aacccgcaaa acaauucaug      660

cgccaagccg ccuaccaagc uggccuagcu ucaccagaaa acucagaaca acuaaucaua      720

gcacucgaac cggaagcagc aagcaucuac ugcagaaaac uacgccucca ccaaaugauc      780

gaacucagcu caaaagccgc cgugaacggc uacuccggau ccgacaccgu aggcgcgggc      840

uucacacaag ccaaagaaca cauccgucgg aaccgccaau cacgaacauu ccuagucgaa      900

aacgucauag gcgaaaucug gagcgaacua gaagaaggcg acaaauacgu cguagucgac      960

ucaggcggag gcacagugga ccucaccgua caucaaaucc gccuaccaga aggccaccuc     1020

aaagaacucu acaaagcuac aggcggacca uacggaucac ugggcgucga cuacgaguuc     1080

gaaaaacuac uauacaagau cuucggcgaa gacuuuaucg aacaauucaa aaucaaaaga     1140

cccgccgccu ggguagaccu caugaucgcc uucgaaucca gaaagagggc agccgcgccc     1200

gaccgcacua acccccugaa cauaacacuc ccauucagcu ucaucgacua uuacaagaaa     1260

uuccgcggcc acucaguuga acacgcccuc cgcaaaucca acguagacuu uguaaaaugg     1320

ucaucccaag gcaugcuccg gauguccccc gacgccauga acgcccuauu caaaccaacc     1380

auagauucca uaaucgaaca ccucagagac cucuuccaaa aacccgaagu cucaaccgua     1440

aaauuccuuu uccuagucgg gggauucgcc gaagcgcccu uacuacaaca agcggugcaa     1500

gcugcauucg gcgaucaaug ccgaauaaua aucccccaag acguaggccu aaccauacug     1560

aaaggggcag uacucuucgg ccucgacccc gcaguaauca aaguccgacg cuccccacua     1620

accuacggcg uaggcguacu caacagauac guagaaggaa aacauccacc agagaaacuc     1680

cugguuaaag acggaaccag auggugcacc gacguauucg acaaauucau cagcgccgac     1740

caaucaguug cacucggcga auuaguuaag cgaagcuaca cccccgcgaa accaucccaa     1800

cucgucaucg ucauaaauau cuacagcuca gaacacgaca acgucucguu caucaccgac     1860

cccgggguca aaaagugcgg cacgcucaga cucgaccuca ccggcaccag cgggacggca     1920

guaccagcgc gacgcgagau acaaacccuc augcaauucg gcgacacaga gaucaaagcc     1980

accgcgauug acauagcaac aucaaaaucu gucaaagucg gaaucgacuu cuuaaacuac     2040

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  2182
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt8)

<400>  2182
gggagaaagc uuaccaugcu cgccgucccc gagaugggcu ugcagggccu auacauaggc       60

agcucacccg aaagaagccc agucccaucc ccaccuggau cccccagaac ccaagaaucc      120

ugcggaaucg cuccccucac cccaucacaa uccccaaaac cggaaguccg cgcaccccaa      180

caggccucau ucucaguugu ugucgccaua gacuucggca caaccucaag cggauacgcc      240

uucagcuucg ccucagaccc cgaagccaua cauaugaugc gcaaauggga ggguggcgac      300

cccggcgucg cccaccagaa aacgcccacu ugccuacucc ucaccccaga aggcgccuuc      360

cacuccuucg gcuacacggc cagagacuac uaccacgacc ucgaccccga agaagcaagg      420

gacugguugu acuucgaaaa auuuaaaaug aaaauucaua gcgccacaga ccuaacccua      480

aaaacgcaau uagaagcugu aaacggcaaa accaugcccg cccucgaagu cuucgcccac      540

gcacuccgcu ucuuccgaga acacgcacuc caagaacuaa gagagcaauc acccagccuc      600

cccgagaaag acacaguacg cuggguacug accguacccg ccauauggaa gcaaccagcg      660

aaacaauuca ugagagaggc cgcauaccuc gcagggcuag uaucccggga aaacgcagaa      720

caacuccuca uagcauuaga accagaagca gccucagucu auugcagaaa acuccgccug      780

caccaauugc ucgaccucag cggccgcgcc ccaggaggcg gucgacucgg cgaacgacga      840

agcauagacu caucauuccg ccaagccaga gaacagcucc gccgauccag acacucacga      900

accuuccuug uagaauccgg cgucggagag cuuugggccg aaaugcaagc cggggaccga      960

uacgucguag ccgacugcgg cggcggaacc gucgaccuaa caguacacca acuagaacaa     1020

ccacauggua cccucaaaga acucuacaaa gccuccggcg gucccuacgg agccguuggc     1080

guagaccucg cauucgaaca acuacucugc agaauauucg gagaagacuu uauagcuacc     1140

uuuaaaagac aacgacccgc agccuggguc gaccuaacua uagccuucga agcacgcaaa     1200

cgaacagccg gcccacacag agccggcgca cucaacauaa gccuaccauu cucguucaua     1260

gacuucuacc gcaagcaaag aggccacaac gucgaaaccg cccucagacg aucauccgua     1320

aacuucguaa aauggucaag ucaaggaaug cugcgaaugu caugcgaagc aaugaacgag     1380

cuauuccaac cgacaguaag cggaaucauc caacacaucg aagcgcuccu agcgcgcccu     1440

gaaguccaag gcguaaaacu ucuauucuua guuggaggau ucgcagaaag cgccguacuu     1500

caacaugcag uccaagcagc acucggcgca cgcgggcucc gagucgucgu cccccacgac     1560

guuggccuaa ccauacucaa aggagccguc cucuucggac aagccccagg ggucguccga     1620

gugcgcagau caccgcuaac auacggcgua ggcgugcuca aucgcuucgu accaggcaga     1680

cacccgcccg aaaaacuccu aguccgagac ggacggcgcu ggugcaccga cgucuucgaa     1740

agauucgucg cggcugaaca auccguagcc cucggcgaag agguacgucg cagcuacugc     1800

ccagcccgac ccggacagag acgaguucuc aucaaccucu acugcugugc agcagaagac     1860

gcccgguuca uaacagaccc cggcguaaga aaaugcggag cacucucccu ugaacuagaa     1920

ccggcagacu gcggacaaga caccgccggc gccccacccg gaagacgcga aaucagagcc     1980

gcaaugcaau ucggagacac agaaaucaaa gucacagcag uagacguaag caccaacaga     2040

agcgucagag caagcauaga cuuccucuca aacuagggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  2183
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt8)

<400>  2183
gggagaaagc uuaccauggc ccgcgaaaug accauacuag gcuccgccgu auuaacccuc       60

cuccuugcag gcuaccuagc acaacaauac cucccacuac caaccccaaa agucauuggc      120

auugaccucg gaaccacgua cugcagcguc ggcgucuucu ucccuggaac cggcaaaguc      180

aaaguaauac ccgacgaaaa cggccacauc uccauaccau ccaugguuuc cuucaccgac      240

aacgacgugu acgucggaua cgaauccguc gaacucgccg acagcaaccc acagaacacc      300

aucuaugacg caaaacgauu caucggaaaa auauucacag ccgaagaacu cgaagccgaa      360

aucggacgcu auccauucaa aguacuaaac aaaaacggca ugguagaguu cuccgucaca      420

agcaacgaaa ccaucaccgu cagccccgag uacguaggau cuagacugcu ucuaaaacua      480

aaagaaaugg ccgaagccua ucugggcaug cccgucgcca acgcaguaau cucggucccc      540

gcagaguucg accuaaaaca acgaaacuca accauagaag cggccaaccu agccggccuc      600

aaaauacuaa gagucauaaa cgaacccacu gccgcggcua uggccuacgg ucuccacaaa      660

gccgacgucu uccacguccu cgucaucgac cucggcggcg gaaccuuaga cgucagccua      720

cucaacaaac aaggcggcau guuccucacc cgcgcaauga gcggcaacaa caaacucgga      780

ggccaagacu ucaaccaacg ccuacuccaa uaccucuaca aacagaucua ccaaaccuac      840

ggcuuuguac caucccgcaa agaagaaaua caccgacucc gacaagccgu cgaaaugguc      900

aaacucaacc ugacccuaca ccaaagcgcc cagcuaucug uacuacuaac cgucgaagaa      960

caagaccgca aagaacccca cucaagcgac accgaacucc ccaaggacaa acucagcucu     1020

gcggacgacc accgcgucaa cuccggcuuc ggccgaggcu uaucagacaa gaaauccgga     1080

gaaagccaag uccucuucga aaccgagaua ucccgcaaac uauucgacac acucaacgaa     1140

gaccuauucc agaaaaucuu aguacccaua caacaagucc ucaaagaagg ccaccuggag     1200

aaaacagaaa uagacgaagu cguccuagua ggcggcagca cacgcauccc ccgcauuaga     1260

caagucaucc aagaguucuu cggcaaagac cccaacaccu ccgucgaccc cgaccuagcc     1320

gucgugaccg ggguagcaau ccaagccggc aucgacggag gcuccuggcc acuacagguc     1380

ucggcacuug aaaucccgaa caaacaccuc cagaaaacca acuucaauua aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2184
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt8)

<400>  2184
gggagaaagc uuaccauggc agcaaucggc guccaccucg gaugcacauc agccugcguc       60

gccgucuaca aagacgggcg cgccggcguc gucgcaaacg acgcgggcga ccgcgucaca      120

ccagccgucg ucgcauacuc cgaaaacgaa gaaauaguag gccuagccgc caagcaaucc      180

cgcauacgca acaucagcaa cacagucaug aaaguaaaac aaauauuagg ccgcuccucc      240

uccgacccac aggcccaaaa auacaucgca gaaucaaaau gccucguaau cgagaaaaac      300

ggcaaacuac gcuacgagau cgacacuggc gaagaaacca aguucguaaa cccagaagac      360

gucgcccgcc uaaucuucuc aaaaaugaaa gaaacggccc acucaguccu cggcuccgac      420

gccaacgaug ucgucauaac cguaccauuc gacuucggcg aaaaacaaaa gaacgcacua      480

ggcgaagccg cccgcgcagc gggauucaac guccuacgcc ucauacacga accauccgcg      540

gcccucuuag cuuacggaau cggacaagac ucccccaccg gcaagucaaa cauccuagua      600

uucaaacuag gaggaaccuc acuaucacuc ucagucaugg agguaaacuc aggcaucuac      660

cgcguccuca gcaccaacac agacgacaac aucggaggag cccacuucac cgaaacacuc      720

gcccaguacc ucgccuccga guuccagcga ucguucaaac augacguacg aggaaacgca      780

cgcgcaauga ugaagcucac gaacagcgca gaagucgcaa agcacucccu aagcacacua      840

ggcagcgcaa acugcuuccu ggacucauua uacgaaggac aggacuucga cugcaacgua      900

agccgcgcca gauucgaacu ccucugcuca ccccucuuca acaaaugcau cgaagccaua      960

cgcggacuac uagaccaaaa cggguucacc gccgacgaca ucaacaaagu cguucucugc     1020

ggcggaucca gccgcauccc caaacugcaa caacucauca aggaccuauu ccccgccguc     1080

gagcugcuaa acuccauacc acccgacgaa guuauaccca uuggagcagc aauagaggcc     1140

ggcauccuca ucggcaaaga gaaccuccuc gucgaagacu cccugaugau cgagugcucc     1200

gccagagaca uacucgucaa aggcgucgac gaaucaggag caucacgcuu cacaguccua     1260

uuccccucug gaacaccccu uccagcacga cgacaacaca cccuacaagc accaggcagc     1320

auuuccuccg ucugccuaga acucuacgaa uccgauggca aaaacucggc caaagaagaa     1380

accaaguucg cacaagucgu acuccaagac cucgacaaga aagaaaacgg acuccgcgac     1440

auccuggccg ugcucaccau gaagcgagau ggaucacuac acgugaccug caccgaccag     1500

gaaaccggca aaugcgaagc caucagcauc gaaaucgcau ccuaaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  2185
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt8)

<400>  2185
gggagaaagc uuaccauguc cgucgucgga cuggacgugg gaagccaaag cugcuacaua       60

gcagucgccc gggcaggggg caucgaaaca aucgccaaug aguucagcga cagaugcacu      120

ccaagcguca ucuccuucgg auccaaaaac agaacaauag gagucgccgc caaaaaccaa      180

cagauaaccc acgcaaacaa caccgucuca aacuucaaac gguuccacgg cagagcauuc      240

aacgaccccu ucauacaaaa agaaaaagaa aaccuaucau acgaccucgu cccacucaaa      300

aacggaggag ucgguaucaa agucauguac augggcgaag aacaccuuuu cucaguagag      360

caaauaacag caaugcuacu aaccaaacuc aaagagacag cagaaaacuc gcugaagaaa      420

ccagucacag auugcgucau aagcgucccg agcuucuuca ccgacgccga acgacgcuca      480

guacuagacg cagcccaaau cgucggccug aacugucuca gacuaaugaa cgauaugacg      540

gcagucgccc uaaacuacgg cauauacaaa caggaccucc caucacugga ugaaaaacca      600

cguaucgugg ucuucgucga caugggccac ucagcauucc aagucuccgc augcgccuuc      660

aacaaaggca aacucaaagu acuaggcaca gccuucgacc cauuccuugg gggcaaaaac      720

uucgacgaaa aacuggucga gcacuuuugc gcagaguuca aaaccaaaua caaacucgac      780

gccaaaagca aaauccgagc acuucuacga uuauaccaag aaugcgaaaa acucaagaaa      840

cucaugagca gcaacucgac agaccucccc uugaacaucg aaugcuucau gaaugacaag      900

gacgugucag ggaagaugaa ccggucacag uucgaagaac ugugcgccga acuccugcag      960

aaaaucgaag ucccacugua cucccuacuc gaacaaaccc accugaaagu cgaagacguc     1020

ucagcaguag aaaucguggg aggggcaacc cgaauaccug ccgucaaaga acguaucgcg     1080

aaauucuucg gaaaagacau caguacaacg cucaacgccg acgaagcagu cgccagaggg     1140

ugcgcacucc aaugcgcgau ccuauccccc gcguucaaag uacgcgaguu cuccgugacu     1200

gacgccgucc cauucccaau cucacuaauc uggaaccacg acucagaaga cacggaagga     1260

guccacgaag ucuucagccg caaccacgcu gcccccuucu cuaaaguauu aaccuuccuc     1320

cgccgagguc cauucgaacu cgaagcguuc uacucagacc cacaaggggu acccuacccg     1380

gaggcgaaaa ucggccgcuu uguaguacaa aacgucucag cccagaaaga cggcgaaaaa     1440

ucccggguca aagucaaagu ccgcgucaac acccacggca uauucaccau cucaacugcc     1500

agcauggucg agaaaguacc aacagaggag aacgaaaugu caagcgaagc cgacauggaa     1560

ugccuaaauc aaagaccgcc agaaaacccu gacaccgaca aaaacguaca acaagacaau     1620

uccgaagcag ggacccagcc acaaguccag acagacgcac aacagaccag ccaaucaccc     1680

ccauccccag agcucacgag cgaagaaaac aaaauaccag acgcagacaa ggcaaacgaa     1740

aagaaagucg accagccgcc agaagcgaaa aagccgaaaa ucaaaguagu caacgucgaa     1800

cuccccauag aagcaaaccu cguauggcag cucgggaaag accuccuaaa cauguacauc     1860

gagacagaag gcaaaaugau aaugcaagac aaacuagaaa aagaaagaaa cgacgcuaaa     1920

aacgcaguag aagaguacgu cuacgaguuc cgcgacaaac ucugugggcc cuacgaaaaa     1980

uucaucugcg aacaagacca ccaaaacuuc cuaagacucc uaaccgaaac ggaagacugg     2040

cucuacgaag aaggcgagga ccaagcaaaa caagccuacg ucgauaaacu cgaggagcua     2100

augaaaaucg gcacgcccgu caaaguccgc uuccaagaag cagaagaacg accgaagaug     2160

uucgaagaac ugggccagcg cuugcaacac uacgcgaaaa uagcggccga cuuccgcaac     2220

aaagacgaaa aauauaacca cauagacgaa ucagagauga aaaagguaga gaaaagcgua     2280

aacgaaguaa uggaauggau gaacaacguc augaacgccc aagccaagaa aucacuagac     2340

caagaccccg uugucagagc ccaagaaaua aaaaccaaaa uuaaagaacu caacaacaca     2400

ugcgagccag ucgucaccca accgaaacca aaaauagaau cuccaaaacu cgaaagaacc     2460

ccaaacggcc cuaacaucga uaagaaagaa gaggaucucg aagacaaaaa caacuucggg     2520

gcagaacccc cgcaccaaaa cggcgaaugc uaccccaacg agaaaaacuc ugugaacaug     2580

gaccuagauu aaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  2186
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt8)

<400>  2186
gggagaaagc uuaccauggc cgacaaaguc cgacgacaac gaccgcgccg acgaguaugu       60

ugggcgcucg ucgccguacu gcucgccgac cuacuggccc uaagugacac ccucgcagug      120

augaguguag accuaggcuc cgaauccaug aaggucgcga uagucaaacc aggagugccg      180

auggaaauag uccucaacaa ggaauccagg cgaaaaaccc caguaauagu aacccucaaa      240

gaaaacgagc gguucuuugg agacucagca gcaagcaugg caaucaagaa uccaaaagcc      300

acccuacgau acuuccaaca ccuacuagga aagcaggcag acaacccaca cgucgcacua      360

uaccaggcca gguucccgga acacgagcug accuucgacc cccaaaggca aacgguacac      420

uuccaaauca gcagccaacu acaauucagc ccagaagaag uccucggaau gguccuaaac      480

uacagcagaa gccucgcaga ggauuucgcc gaacagccaa uaaaagacgc cguaauaaca      540

gucccaguau ucuucaacca agccgagcga cgagccgucc uacaggcagc acgcauggcc      600

gggcucaagg uacuccagcu aauaaacgac aacacggcaa cggcccuauc cuacggaguc      660

uuucggagaa aagacauaaa cacaaccgca caaaacauaa uguucuacga caugggcuca      720

ggcucgacag ucugcacaau agucacauac cagaugguca aaacaaagga agccgggaug      780

caaccgcaac ugcaaauacg aggagucgga uucgaccgaa cacugggagg acuagaaaug      840

gaacuacgac uccgagagag gcuggccggc cuauucaacg aacaaagaaa aggccaacgc      900

gcaaaagacg uaagggaaaa cccacgagca auggcuaaac uacuccgaga agccaaccga      960

cugaaaacag uacuaagcgc aaacgcagac cacauggcgc aaauugaagg gcuaauggac     1020

gacguagacu ucaaagcaaa agucacccgc guggaguucg aggaacucug cgcagaccug     1080

uuugaacgcg uccccggccc cguacaacaa gcacugcaaa gcgcagaaau gagccuagac     1140

gagauagaac aaguaauccu aguaggcggc gccacacgag uacccagagu ucaagaggua     1200

cuacugaaag cugucgggaa agaggaacua ggcaaaaaca ucaacgccga cgaggccgca     1260

gcaaugggag ccguauauca agcagcagca uuaaguaaag cauucaaggu aaagccguuu     1320

guaguacggg acgccgucgu auacccaauu uuagucgagu ucacgcggga agucgaagag     1380

gaacccggaa uacacucacu gaaacacaac aaacgcgucc uauucucacg aauggguccc     1440

uacccacaaa gaaaaguaau aaccuucaac cgauacagcc acgacuucaa uuuccacauc     1500

aacuacggcg accuuggauu ccuagggccc gaagaccuga gagucuucgg aagccagaac     1560

cucaccacag ucaaacugaa aggagugggg gacagcuuca agaaauaccc agacuaugaa     1620

ucaaaaggaa uaaaggcaca cuucaaccuc gaugaaagcg gaguacugag ccuggacagg     1680

guagaaagcg uuuucgagac acugguggaa gacagugccg aagaagagag cacacuaaca     1740

aaacugggca acacaaucag uagccucuuc gggggcggaa caacgccaga cgcaaaagaa     1800

aacgggaccg acaccguaca agaagaagaa gaaagcccag ccgaaggaag caaggacgag     1860

ccaggagagc agguagagcu caaagaagaa gcagaggcgc ccguagaaga cggcucucag     1920

ccaccuccgc ccgaacccaa aggagacgca acaccagagg gagagaaggc gaccgaaaaa     1980

gaaaacggcg acaaaagcga ggcgcaaaaa ccgucggaga aagccgaggc gggaccagaa     2040

ggaguagccc cagcacccga aggcgaaaag aaacaaaaac cagcgagaaa aagaaggaug     2100

guggaggaaa ucggcgugga acugguagug cuagauuuac ccgaccuccc agaagacaaa     2160

cucgcgcagu cgguacagaa auuacaagac cugacacuaa gagaucuuga aaaacaagaa     2220

cgagagaagg cggcaaacag ucuggaagcg uucaucuucg agacgcagga caaacuauac     2280

cagccggagu accaagaggu aucaaccgaa gaacaaagag aggaaaucuc cggcaagcua     2340

ucggcggccu caacauggcu cgaggaugaa gggguaggcg ccaccacagu gaugcuaaaa     2400

gaaaagcuag cugaacuaag aaaacuaugc caaggucuau uuuuccgagu cgaggaaagg     2460

aagaaauggc cagaaagacu aucggcccuc gacaaccuac uaaaccacuc cagcauguuu     2520

cuaaaaggcg cgagacuaau accagagaug gaccaaaucu ucacggaagu cgaaaugacc     2580

acacuagaaa aagugauaaa cgagacgugg gcauggaaaa augccacacu cgcagaacaa     2640

gccaaacuac ccgcaacgga aaagcccguc cuacucagca aagacaucga agcaaaaaug     2700

auggcguuag accgcgaagu acaguaccua cuaaacaaag cgaaauucac caaaccacga     2760

ccccgcccca aagacaaaaa cggcacacgg gcagagccac cacugaacgc aagcgccuca     2820

gaccaagggg aaaaggucau acccccggcc ggacaaaccg aagacgcgga accaauaagc     2880

gagcccgaaa agguggagac gggaagcgaa cccggcgaca cagagccacu ggaacuagga     2940

ggcccgggcg cagaaccaga gcaaaaggaa caaagcacag ggcaaaagag gccacucaaa     3000

aacgaugaac uauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2187
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt8)

<400>  2187
gggagaaagc uuaccaugcc agaagaaacg caaacgcaag accaaccaau ggaagaggag       60

gaaguagaaa cguucgccuu ccaggcagag aucgcccaac uaaugagccu gauaauaaac      120

acauucuacu cgaacaaaga gauauuccuc agagagcuca uaagcaacag cucggacgca      180

cuggacaaaa uacgauacga aucccuaacc gacccgagca aacucgacuc cggcaaagaa      240

cuccacauca accuaauacc aaauaaacag gaccggacac ucaccaucgu cgacacaggg      300

auaggaauga caaaagcgga ccugaucaac aaccuaggaa cgauugcaaa aagcggaaca      360

aaagcguuca uggaagcccu ccaagcaggc gccgauauau ccaugauagg acaauucggc      420

gugggguucu acucagcaua cuuagucgcg gaaaaaguca cgguaauaac gaaacacaac      480

gacgacgaac aguacgcgug ggagagcucc gcaggcggca gcuucacagu uaggacagac      540

accggagagc ccauggggcg agggaccaag gucauccuuc accucaaaga agaccaaacg      600

gaauaccucg aagaaaggcg cauaaaggaa aucgugaaga aacacuccca auucauagga      660

uacccuauca cacuauucgu agaaaaagaa cgcgacaaag agguaagcga cgacgaagcg      720

gaagagaagg aagacaagga agaggaaaaa gagaaggaag agaaagaaag cgaagacaag      780

cccgaaauag aagacguagg cucggacgag gaagaagaaa agaaagacgg cgacaaaaag      840

aagaaaaaga aaauaaaaga aaaauacauu gaccaggagg aacucaacaa aacgaaaccg      900

auauggacca ggaacccgga cgacaucaca aacgaagaau acggggaguu cuacaaaucg      960

cucacaaacg acugggaaga ccaccuagcg gucaaacacu ucagugugga gggacaacua     1020

gaguucagag cacuccuguu cgucccaagg cgagccccau ucgaccuauu cgaaaaccgc     1080

aaaaagaaaa acaacauaaa acucuacguc agaagagucu uuauaaugga caacugcgag     1140

gaacuaaucc ccgaauaccu aaauuucauc cgaggggucg uggacucuga agaccuccca     1200

cuaaacaucu caagagaaau gcugcagcaa aguaagaucc uaaaagugau ccgcaaaaac     1260

cuaguaaaga aaugccugga acuguucacg gaacuggcgg aggauaaaga aaacuacaaa     1320

aaguucuacg aacaauucuc caagaacauu aaacugggga uccacgaaga cucccaaaac     1380

agaaagaaac ugagcgaacu ccugcgauac uacaccagcg cguccggaga cgagaugguc     1440

agccuaaagg acuacugcac cagaaugaaa gaaaaccaaa aacacaucua cuauauaaca     1500

ggggaaacca aggaccaagu cgcaaacagc gccuuuguag agcgccugag aaaacacgga     1560

cucgaaguca uauacaugau agaaccaauc gacgaauacu gcguacagca gcugaaggag     1620

uucgaaggaa aaacgcuagu aucgguaacg aaagagggac uagagcuacc cgaagacgag     1680

gaagagaaaa agaaacaaga agaaaagaaa accaaauucg agaaccucug caaaauaaug     1740

aaagacaucc uagaaaagaa aguagaaaaa gucguagugu caaaccgccu cgucacgagc     1800

ccauguugca uagucacguc aaccuacgga uggacagcca acauggagag gauaaugaaa     1860

gcccaagccc uacgagacaa cucaacaaug ggauacaugg ccgccaagaa acaccuagaa     1920

auaaaccccg accauucgau aauagagacu cuccgacaaa aagccgaggc cgacaagaac     1980

gacaagagcg uaaaagaccu gguaauccuc cucuacgaaa cggcccuccu aucaagcggg     2040

uucagccuag aagacccaca aacccacgcc aaccgcaucu acagaaugau aaaacuagga     2100

cucggaaucg acgaagacga cccgaccgcg gacgacaccu cagcagcggu aacagaggaa     2160

augcccccac uagaagggga cgacgacacg agcagaaugg aggaaguaga cuaaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  2188
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt8)

<400>  2188
gggagaaagc uuaccaugga cuccucaaaa cuagacuccg gcaaaggacu ccacaucaac       60

cucgucccca acaaacaaaa ccaaacacuc accauaguag acacacgcau cggcaugacc      120

aaaacagacc ucaucaacaa ccucggcacc gucaccaaau ccggaacaaa agccuucaug      180

gaagcacucc aagccgacgc agacaucucc augaucggac acuucggcgu cggcuucuac      240

ucagcauacc ucgucgccaa aaaagucacc guaaucucaa aacacaacaa cgacgaacaa      300

uacaccuggg aauccuccgc aggcggcucc uucaccguac gaacagacga auaaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  2189
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt8)

<400>  2189
gggagaaagc uuaccaugcc cgaagaggua caccauggug aagaggaagu cgagaccuuc       60

gccuuccaag ccgaaauagc acaauuaaug agccugauaa ucaacaccuu cuacucgaac      120

aaagaaaucu uccugcgcga acucaucucg aacgcaagcg acgcccuaga caagauaaga      180

uacgaaucac ugacagaccc cagcaagcua gacucaggga aggagcucaa aaucgacauc      240

auuccaaacc cccaagaacg gacacuaacc cugguggaca cagggaucgg gaugaccaag      300

gccgaccuga uaaacaaccu cgggacaauc gccaaaagcg gcaccaaagc guuuauggag      360

gcccuacaag ccggagccga caucagcaug aucgggcaau ucggcgucgg auucuacagc      420

gccuaucuag uagcggaaaa aguaguagug aucacaaaac acaacgacga cgaacaauac      480

gccugggaaa gcagugcagg aggcagcuuc acggugcgag ccgaucacgg agaacccaua      540

ggacggggca ccaaggugau acugcaccuc aaagaagacc aaaccgaaua ccuggaagaa      600

cgacgaguaa aggaggucgu aaagaagcac agccaauuca uaggcuaccc aauaaccuug      660

uaccuagaga aagaacggga aaaagagaua agugacgacg aagcugaaga agaaaaaggc      720

gaaaaagaag aagaagacaa agacgacgaa gaaaagccca aaaucgagga cguaggcagc      780

gacgaagaag acgacagcgg aaaagacaag aaaaagaaaa caaagaaaau aaaagagaag      840

uacaucgacc aagaagaacu caacaaaacg aagcccauau ggacaagaaa uccagacgau      900

aucacgcaag aagaauacgg agaguucuau aagagucuaa ccaacgacug ggaagaccac      960

cuagcgguca aacacuucag cgucgaagga cagcuagagu uccgagcccu gcuauucauc     1020

ccccgaaggg cacccuucga ccuauuugaa aacaaaaaga agaaaaacaa cauuaaacuc     1080

uacguacgcc gcgucuucau aauggacagc ugcgacgaac uaauaccaga auaccugaac     1140

uucauccgcg gagucgucga cagcgaagac cuaccacuga acauaucacg agaaaugcug     1200

caacaaagca aaauccucaa agucauacgc aaaaacaucg uaaagaaaug ccuugaacua     1260

uuuucggaac uggcagaaga caaagaaaau uacaagaaau ucuacgaagc cuucagcaaa     1320

aaccucaaac ugggaaucca cgaagacucc acaaaccgaa gaagacuaag cgaacuccua     1380

agauaccaca ccagucaaag cggcgacgaa augacaagcc ucucagaaua cgugucccga     1440

augaaagaaa cccagaaaag caucuacuac aucacgggcg aaagcaaaga acaaguagca     1500

aacagugcuu ucguagaacg ggugagaaag cgaggauucg aagucgugua uaugaccgaa     1560

ccaaucgacg aauacugcgu acaacaacua aaagaguucg auggcaaguc ccucguauca     1620

gucacgaaag aaggccuaga acugccggaa gacgaagaag agaaaaagaa aauggaagaa     1680

agcaaagcaa aauucgaaaa ccugugcaaa cucaugaaag aaauacucga caagaaaguc     1740

gaaaaaguaa caauaagcaa ccggcuagug agcagcccau gcugcaucgu cacaagcaca     1800

uacggcugga cggcgaacau ggaaagaaua augaaagcac aagcccuacg agacaacagc     1860

acgaugggau acaugauggc aaagaagcac cuagaaauca acccagacca cccaaucgug     1920

gaaacacucc gacaaaaagc cgaagcagac aagaacgaca aggccguaaa agaucuagug     1980

guacuacugu ucgaaaccgc gcuacucagc ucaggauuca gccucgagga cccacaaacc     2040

cacucgaaca ggaucuacag aaugaucaaa cuaggccugg gaauagacga agacgaaguc     2100

gccgccgaag aacccaacgc ggcaguccca gacgaaaucc caccauugga gggagacgaa     2160

gacgcaagca ggauggagga aguagacuaa ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  2190
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt8)

<400>  2190
gggagaaagc uuaccaugag ggcguuaugg guccuagggc ugugcugcgu ccuccugacg       60

uucggcagcg ucagagcaga cgacgaagug gacguagacg gcaccguaga agaagaccug      120

ggaaaaucca gagaggguag cagaaccgac gaugaagucg ugcagcgaga ggaagaagcc      180

auccaacucg acgggcugaa cgcgucacag auacgggaac uacgagagaa aagcgaaaaa      240

uucgccuucc aagcagaagu caaccgaaug augaaguuaa ucauaaacuc acuauacaaa      300

aauaaagaaa uauuccucag agaacugaua agcaacgcga gugacgcacu agacaaaauc      360

agacucauca gccucaccga cgaaaacgcc cuuaguggga acgaagaacu aacagucaaa      420

aucaaaugcg acaaggaaaa gaaccuacua cacguaacag acacgggugu aggaaugacc      480

cgggaggaac ucgucaaaaa ccucggcacc auagcgaaaa gcggaacauc agaguuccuc      540

aacaaaauga cagaggccca ggaagacgga caaagcacca gcgaacugau cgggcaauuc      600

ggaguaggau ucuacagcgc guuccucgug gcagauaagg ucaucgucac cucaaaacac      660

aacaacgaca cccagcacau augggagagc gacagcaacg aguucuccgu aaucgcggac      720

ccccgcggga acacgcucgg ccgcggaacc acaaucacac ucguacucaa agaagaagca      780

agcgacuacc uagagcucga uacaauaaag aaccugguga aaaaguacag ccaguucauc      840

aacuucccaa ucuacguaug gagcagcaaa acugagacgg uagaagaacc aauggaagaa      900

gaggaagcag ccaaagaaga aaaagaagag ucggacgacg aggcagcggu agaagaagaa      960

gaagaagaga agaaaccgaa aaccaagaaa guagagaaaa cgguauggga uugggaacua     1020

augaacgaca ucaaacccau auggcagcgc cccagcaaag aagucgaaga agacgaauac     1080

aaggcauucu acaagagcuu cagcaaagaa agugacgacc cgauggccua cauacacuuc     1140

accgcagaag gggaaguaac auucaagagc auacuauucg ucccaaccuc agcgccgcga     1200

ggacucuucg acgaguacgg gagcaagaaa agcgacuaca ucaaacugua cguaagacgc     1260

guauucauaa ccgacgacuu ccacgacaug augcccaaau accuaaacuu ugugaaaggg     1320

guaguagaca gcgacgaccu accccuaaac guguccagag aaacccucca gcagcacaaa     1380

cuccugaagg uaauaaggaa gaaacuggug cggaaaacac uagacaugau aaagaaaaua     1440

gccgacgaca aguacaacga caccuucugg aaggaguucg gcaccaacau aaaacuaggg     1500

gugaucgaag accauagcaa ccggacccga cucgcaaaac uccuaagauu ccaaucaagc     1560

caccacccca ccgacauaac gagccucgac caguacgugg aaaggaugaa ggaaaagcaa     1620

gauaaaaucu acuuuauggc gggcuccucc cgaaaagaag cagaaagcuc acccuucgua     1680

gagcgacuac ucaagaaagg guacgaaguu auauaccuga cagaaccugu ggacgaauac     1740

ugcauacaag cacugccgga guucgauggc aaacgcuucc aaaacguggc aaaagaaggc     1800

guaaaauucg acgaaagcga gaaaacgaaa gaaucacgcg aagcaguaga aaaagaguuc     1860

gaaccccuac ucaauuggau gaaagacaaa gcauuaaaag acaaaauaga aaaagcagua     1920

gugagccaac gcuugaccga aagcccgugu gcccucguag caagccagua cggcuggagc     1980

gggaacaugg agagaaucau gaaagcgcag gcguaccaaa caggaaaaga cauauccacc     2040

aacuacuacg cuucacaaaa gaaaaccuuc gaaauaaacc caagacaucc gcuaauccgc     2100

gacaugcugc gacgaauaaa ggaggacgaa gacgacaaga caguacucga ccucgcaguc     2160

guccucuucg aaaccgcaac gcuacgguca ggcuaccugc ucccagacac gaaagcauac     2220

ggagacagga uagagaggau gcucagacua agccuaaaca uagacccgga cgccaaggua     2280

gaagaagaac cagaggaaga accggaagaa acggcagaag acaccacaga ggacacagag     2340

caagacgagg acgaggaaau ggacguagga acugaugaag aagaagaaac ggccaaagaa     2400

ucgacagcag aaaaggacga acuauaagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  2191
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt8)

<400>  2191
gggagaaagc uuaccauggc acgagaacua agggcccucc uccuuugggg ccgacgccuc       60

cgcccgcuac uucgcgcgcc agcacuggca gcugucccag gaggcaaacc cauccuaugc      120

ccccgccgaa caaccgcaca gcucgguccc agacgcaacc cagcuugguc ccuucaagca      180

ggccgccucu ucuccacuca aacagcagaa gacaaagaag aaccacucca cagcauaauc      240

ucaucaaccg aaucaguaca aggcucaaca ucuaaacacg aguuccaagc cgaaacuaag      300

aaacugcucg acauaguggc cagaucccua uacuccgaaa aagaagucuu cauccgcgaa      360

uugaucucaa acgcauccga cgcacucgaa aaacuacgac acaaacucgu cuccgacggc      420

caagcccucc cagaaaugga aauccaucug caaacuaacg ccgaaaaagg caccauaaca      480

auccaggaca caggcaucgg caugacccaa gaggaacuug ucuccaaccu cggaacaauc      540

gcccgcagcg gauccaaagc auuccucgac gcccuacaaa accaagcaga agcaagcucc      600

aaaaucaucg gacaauucgg agucggcuuc uacucagccu ucauggucgc cgaccgcguc      660

gaaguguacu cacgcucagc ugcacccgga agucuaggcu aucaauggcu aucagacgga      720

agcggggucu ucgaaaucgc agaagccucu ggcgugcgca caggcaccaa aaucaucauc      780

caccugaaau ccgacugcaa agaguucucg agcgaagcac gagucaggga cguuguaacc      840

aaauacucaa acuucguauc cuuuccacua uaccucaaug gccgucgaau gaacacccuc      900

caagcaaucu ggaugaugga cccuaaagac guaagagaau ggcaacacga agaguucuac      960

cgcuacguug cccaagcuca cgacaaacca cguuacaccc ugcacuacaa aaccgacgca     1020

ccccugaaua uccgaagcau uuucuacguc cccgacauga aacccucuau guucgacgua     1080

ucccgcgaac ucggcuccuc agucgcccua uacucccgca aaguccuuau acaaaccaaa     1140

gccaccgaca uacucccaaa auggcuccgc uuuauacgag gagucgucga cucagaagac     1200

aucccgcuca accugagccg agaacuacuc caagaauccg cccucauucg caaacugcgu     1260

gacguccucc aacaacgccu caucaaauuc uucaucgacc aaucaaagaa agacgccgaa     1320

aaauacgcua aauucuucga agacuacggc cuauucaugc gcgaaggaau cgugaccgcc     1380

acagaacaag aggucaaaga agacauagcc aaacuccuaa gauacgaauc cuccgcacug     1440

cccucgggac aauuaaccuc acuauccgaa uacgcaagcc guaugcgcgc cgggacccgc     1500

aacaucuacu accucugcgc ccccaaccga caccuggcag agcacucccc auacuacgag     1560

gcaaugaaaa agaaagacac cgaaguccuu uucugcuucg aacaauucga cgaacuaacc     1620

cucuuacacc uaagggaguu cgacaaaaag aaacucaucu caguggaaac ggacaucgua     1680

gucgaccacu acaaagaaga aaaauucgaa gaccgcucac cagccgcaga augucuaucc     1740

gaaaaagaaa cagaagaacu cauggccugg augcgcaacg uccuaggcag ucgcgucaca     1800

aacgucaaag uaacccuuag acuugacacc caucccgcca ugguaacagu ccucgaaaug     1860

ggagccgcac gccacuuccu aagaaugcag caacuagcca aaacacaaga agaaagagcc     1920

caacuccuac aaccuacacu agaaaucaac ccccgccacg cacucaucaa gaaacuaaac     1980

caacuacgcg caagcgaacc aggccuagcg caacuccuag uagaccaaau cuacgaaaac     2040

gccaugauag cagcaggccu aguagacgac ccccgcgcca uggucggccg ccucaacgaa     2100

cuccuaguaa aagcccucga aagacacuaa ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  2192
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt8)

<400>  2192
gggagaaagc uuaccauggg caaaaucucc ucacucccca cacaacuauu caaaugcugc       60

uucugcgacu uccucaaagu caaaaugcac acaauguccu ccucacaccu cuucuaccua      120

gcccucugcc uacucaccuu cacaucauca gccacagccg gcccugaaac cuuaugcgga      180

gccgaacucg uagacgcccu ccaauucguc ugcggagacc gaggcuucua cuucaacaaa      240

cccaccgguu acggaucauc aucccgccgc gccccacaaa caggcaucgu cgacgaaugc      300

ugcuuccgcu caugcgaccu ccgaagacua gaaauguacu gcgcaccccu caaacccgcc      360

aaauccgccc gcuccguccg agcccaacgc cacacagaca ugcccaaaac acaaaaagaa      420

guccaccuca aaaacgccuc ccgaggaucc gccggcaaca aaaacuaccg cauguaagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  2193
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt8)

<400>  2193
gggagaaagc uuaccauggg cauaccaaug ggcaaaucca ugcuaguacu ccuaaccuuc       60

cuugccuucg cauccugcug cauagccgcc uaccgacccu ccgaaacacu cugcggcggc      120

gaauuagucg acacccuaca auucgucugc ggcgaccgcg gcuucuacuu cucccgacca      180

gccucccgcg ucuccagacg cucacgcggc aucguagaag aaugcugcuu ccgaucaugc      240

gaccucgccc uccucgaaac cuacugcgcc acccccgcaa aaucagaacg agacgucuca      300

accccaccca ccguccuccc cgacaacuuc cccagauacc ccguaggcaa auucuuccaa      360

uacgacaccu ggaaacaauc cacccaaaga cuuagacgcg gccuccccgc ccuacuccga      420

gcccgccgcg gacacguacu cgccaaagaa cucgaagccu uccgcgaagc caaacgccac      480

cgcccacuca ucgcccuacc cacacaagac cccgcccacg gcggcgcacc cccagaaaug      540

gccucaaacc gaaaauaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  2194
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt8)

<400>  2194
gggagaaagc uuaccaugaa cuccuucucc acaucagccu ucggccccgu cgccuucucc       60

cucggacucc uccuuguccu cccagccgcc uuccccgccc cagucccccc cggcgaagac      120

ucaaaagacg uagccgcccc ccaccgacaa ccccuuaccu ccuccgaacg caucgacaaa      180

caaauacgau acauccuaga cggcaucuca gcccuccgca aagaaaccug caacaaaucc      240

aacaugugcg aaucuuccaa agaagcccua gccgaaaaca accucaaccu ccccaaaaug      300

gccgaaaaag acggcugcuu ccaaucagga uucaacgaag aaaccugccu ugucaaaauc      360

aucaccggcc uccucgaauu cgaagucuac cucgaauacc uccaaaaccg cuucgaauca      420

uccgaagaac aagcccgcgc cguccaaaug ucaacaaaag uccucauaca auuccuccaa      480

aaaaaagcca aaaaccucga cgccauaacc acccccgacc ccaccaccaa cgccucacua      540

cuaaccaaac uccaagccca aaaccaaugg cuacaagaca ugaccaccca ccucauccuc      600

cgcuccuuca aagaauuccu acaaagcucc cuccgcgccc uacgccaaau guaaggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  2195
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt8)

<400>  2195
gggagaaagc uuaccaugcc acuacuaugg cuccgcggcu uccuacuggc cucaugcugg       60

aucaucguac gcagcagccc cacaccagga agcgagggac acagcgcagc cccagacugc      120

ccaagcugcg cccuagcggc ccugccaaaa gacguaccca acagccaacc cgaaauggua      180

gaagccguca aaaaacacau acuaaacaug cuacaccuaa aaaaaaggcc agacguaaca      240

caacccgucc caaaagcagc acuacucaac gcaauccgca aacuccacgu cgggaaaguc      300

ggagaaaacg gauacguaga gauagaagac gacaucgggc gccgcgccga aaugaacgaa      360

cucauggaac aaaccucaga gauaaucacg uucgccgaaa gcggaacagc ccgcaaaaca      420

cuacacuucg aaauaagcaa agaaggcagc gaccuaagcg ucgucgagcg cgcagaaguc      480

uggcucuucc ucaaaguacc caaagcaaac cgcacacgaa caaaagucac aauacgacug      540

uuccagcaac aaaagcaccc acaaggcucc cucgacacag gcgaagaagc agaagaagua      600

ggccuaaaag gagaacggag cgaacuacuc cuaucagaaa aagucguaga cgcacgcaaa      660

agcacguggc acgucuuccc aguaagcagc agcauacaac gacuacucga ccaaggcaaa      720

agcagccucg acgucagaau agcaugcgaa caaugccaag aaucaggcgc cucccucguc      780

cuacugggaa aaaaaaagaa aaaagaagaa gaaggcgaag gaaagaaaaa aggcggugga      840

gaaggaggcg caggagcgga cgaggaaaaa gaacaauccc accgcccauu ucuaaugcug      900

caagcacggc aaucagaaga ccacccccac cgccgccgac gacgaggacu agaaugcgac      960

ggaaaaguca acaucugcug caaaaaacaa uucuucguca gcuucaaaga cauaggaugg     1020

aacgacugga uaauagcgcc aagcggauac cacgcaaacu acugcgaagg cgaaugcccc     1080

agccacauag caggcacaag cgggagcagc cugucguucc acagcaccgu gaucaaccac     1140

uacagaauga gaggacacuc cccauucgca aaccugaaau cgugcugcgu ccccaccaaa     1200

cuacgaccga ugagcaugcu cuacuacgac gacggacaga acaucauaaa aaaagacaua     1260

caaaauauga ucguggaaga gugcggaugc agcuaaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  2196
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt8)

<400>  2196
gggagaaagc uuaccaugga cggccugcca ggccgagcgu uaggcgccgc cugccuccua       60

cuccuagcag caggcuggcu cggccccgaa gccuggggau caccaacccc accaccaacc      120

cccgcagccc cucccccacc cccaccaccc ggcagucccg gcggaucaca agauaccugc      180

accucaugcg gcggauuccg cagaccagaa gaacucggac gcguagacgg agacuuccuc      240

gaagccguaa aaagacacau acuaucccgc cuccaaaugc gcggccgacc caacaucaca      300

cacgccgucc ccaaagccgc cauggucacc gcccuacgca aacuacacgc cggcaaaguu      360

cgcgaggacg gccgagucga aaucccacac cucgacggcc acgccucccc cggcgcagac      420

ggacaagaac gaguuagcga aaucaucucc uuugccgaaa cagacggccu agccucauca      480

cgaguccgac ucuacuuuuu caucuccaac gaaggaaacc aaaaccucuu cgucguacaa      540

gcaucccuau ggcuauaccu aaaacuccua cccuacgucu uagaaaaagg aucccgccgc      600

aaaguccgcg ucaaagucua cuuccaagaa cagggccacg gcgaccgcug gaacaugguc      660

gaaaaacgcg uagaccucaa acgcuccggc uggcacaccu ucccccuaac cgaagccauc      720

caagcccucu ucgaacgcgg cgaacgacgc cuaaaccucg acguacagug cgacucaugc      780

caagaacucg ccguaguacc cguauucguc gacccagggg aagaaagcca cagaccauuc      840

gucgucgucc aagccagacu cggcgacucc cgacaccgca uacgcaaacg aggccucgaa      900

ugcgacggcc gcacaaaccu cuguugccgc caacaauucu ucaucgacuu ccgccuaauc      960

gguuggaacg acuggauuau agccccaaca ggauacuacg gcaacuacug cgaaggguca     1020

ugccccgccu accuagccgg aguccccggc ucugccagcu cauuccacac agcagucgug     1080

aaccaauacc gcaugcgagg ccuaaacccc ggcaccguaa acucuugcug cauccccaca     1140

aaauuaucaa ccauguccau gcuuuacuuc gacgacgaau acaacauagu caaacgcgac     1200

guccccaaca ugauaguaga agaaugcggc ugcgccuaag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  2197
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt8)

<400>  2197
gggagaaagc uuaccauggc acuucgcguc cuccuccuua ccgcccuaac ccuaugucau       60

ggauucaacc ucgacaccga aaaugccaug accuuucaag aaaacgcccg cggauucggc      120

cagucuguag uacagcucca aggaucuaga guagucgucg gugccccuca agaaaucgua      180

gcagcaaacc aacgcgguag ucuauaccaa ugugacuacu cuacuggcuc gugcgaaccu      240

aucaggcucc aaguccccgu ggaagccguc aacauguccu uaggacuauc acuggccgcc      300

accaccuccc caccgcaacu ccuagccugc ggacccaccg uacaccaaac auguagcgaa      360

aacacguacg ucaaaggacu cuguuuucuc uucggcagca accuacgcca acaaccccaa      420

aaauucccug aagcccucag aggcugccca caagaagacu ccgacauagc cuuccucauc      480

gacggauccg gcuccauuau accccacgac uuccggagga ugaaagaauu ugucucgacg      540

guaauggagc aacucaagaa aucaaaaaca cuguucagcc uaaugcaaua cucggaggag      600

uuccgaaucc acuucaccuu caaagaguuc caaaacaacc ccaacccccg uagccuuguu      660

aaacccauaa cccaacuacu gggccgaaca cacaccgcca ccggcauccg caaagucguc      720

cgcgaacuau ucaacauaac caacggcgca cgcaaaaaug cuuucaagau acuuguagua      780

aucacagacg gagaaaaauu cggagaccca uugggauacg aagacgucau uccugaagcc      840

gaccgagaag gcguaaucag auacgugaua gguguaggcg acgcauucag aucagaaaaa      900

ucacgccaag aacuaaacac aauagccucc aagccacccc gagaccaugu cuuccaggua      960

aacaauuucg aggcacuuaa aacuauucag aaccagcucc gugagaaaau cuucgccauc     1020

gaaggaacuc agacaggauc cuccucgucu uucgaacaug agaugagcca agaaggcuuc     1080

agcgcugcca ucaccucuaa cggacccuug cuaucuacag ucggcuccua cgacugggcc     1140

ggcggcgugu uccucuacac cuccaaagaa aaauccacgu ucauaaacau gacacgaguc     1200

gacucggaca ugaaugacgc guaccuuggu uaugcugccg caauuauacu uagaaaccgu     1260

gugcaauccc uuguacucgg cgcucccaga uaucaacaca ucggccucgu cgcuauguuu     1320

cgucaaaaua ccgggaugug ggaauccaac gccaauguca aaggcaccca aaucggcgcc     1380

uacuucggcg cgagccuaug cucagucgac gucgacucaa acggauccac cgaucuaguc     1440

cugaucggag caccacacua uuacgaacaa accagaggcg gccagguauc agucugccca     1500

cucccccgag gccgcgcccg cuggcaaugc gacgccgucc uuuacggcga gcagggccag     1560

ccuuggggac gauucggagc cgcccucacc guacucggug acguuaacgg agauaaacua     1620

acagacgucg caaucggcgc ccccggagaa gaagacaaca gaggagcggu cuaccucuuu     1680

cacggaaccu ccgggagcgg aaucagcccg ucccauuccc agcgcauugc agguagcaaa     1740

cucagucccc gccuccagua cuucggccaa ucccuguccg gcggccaaga ccuuacaaug     1800

gacggccuag uagaccucac cgucggugcu cagggccaug uccugcuucu acgcucucaa     1860

ccagucuuac gaguaaaagc aauaauggag uucaacccac gcgaagucgc ccgcaacguc     1920

uucgaaugca acgaccaggu cguaaaaggc aaagaagccg gagaaguccg uguaugccug     1980

cacguacaaa aguccacccg cgaccgccua cgggaaggcc aaauacaguc ugucgucacu     2040

uaugaccucg cucucgacuc cggaagaccg cacucucggg ccgucuuuaa cgaaaccaaa     2100

aacucaacac gacgacaaac acaggugcuc ggccugacgc agacaugcga gacgcucaaa     2160

uugcagcuac caaacugcau cgaagaccca guaagcccua uuguccuucg ccuaaacuuc     2220

agccucgugg ggacaccacu aagcgccuuc ggcaaccuac gcccgguacu cgcggaagac     2280

gcccagcgcc ucuucaccgc ccuuuuuccc uucgagaaaa acugcggcaa cgauaacauc     2340

ugccaagacg aucugucgau caccuucagc uucauguccc ucgacugucu cguagucgga     2400

ggcccccgug aguucaacgu aaccguaacc guccgcaacg acggagaaga cagcuaccgc     2460

acucagguca ccuuuuucuu cccccucgac cugucuuaca gaaaaguauc aacacuccaa     2520

aaccaacgau cccaacguuc auggcgacua gccugcgaau ccgccagcuc cacugaaguc     2580

agcggcgccc ucaaaagcac guccugcucg aucaaccacc ccauauuccc cgagaacuca     2640

gaagucacau ucaacaucac auucgacgua gauucaaagg cuucacucgg aaauaaacug     2700

cuucucaaag ccaacgucac cucagaaaau aauaugcccc guacuaacaa aaccgaguuu     2760

caacuagaac ucccggucaa auacgccguc uacaugguag uaaccucuca cggaguaucc     2820

accaaguacc ucaacuucac ugcauccgaa aacacuucuc gcgucaugca gcaccaauau     2880

caagucucca accucgguca acguucacug cccaucuccc uaguauuccu ggucccagua     2940

cgccuaaacc agaccgucau augggacaga ccccaaguca ccuucucaga aaaccuuagc     3000

ucuaccugcc auacaaagga aagauuaccc ucacacuccg acuuucucgc agagcucagg     3060

aaagcccccg uagucaacug cucgauagca guaugccaac gaauacaaug cgauauccca     3120

uucuuuggca uccaggaaga guucaacgcc acccugaagg guaaccucuc auucgacugg     3180

uacauaaaga caucacauaa ccaucuacuu auagucagca cagccgaaau ccuguucaac     3240

gacucagugu ucacccuccu gcccggccaa ggagccuucg uacgcucaca aaccgaaaca     3300

aaaguugaac cuuucgaagu ucccaacccc cuuccgcuca uagucggcuc cucagucgga     3360

ggccuccucc uacucgcccu aauaaccgca gccuuguaca aacucggauu cuucaaacgc     3420

caguacaaag acaugauguc agaaggaggu ccucccggcg cagaaccaca auagggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  2198
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt8)

<400>  2198
gggagaaagc uuaccauguu cucacuaaaa acccuacccu uucuccuacu ccuucacguc       60

cagauaucaa aagccuuccc cgucuccucu aaagagaaaa acaccaaaac cgugcaagac      120

uaccucgaaa aauucuacca acucccgucc aaccaauacc aaucaacacg caaaaacggc      180

acuaacguaa ucgucgaaaa auugaaagaa augcaacgau ucuucggccu caacgucacc      240

ggcaaaccca acgaagaaac ccucgacaug augaagaaac cccgaugcgg aguacccgac      300

ucuggcggcu ucaugcucac ucccggcaau cccaaauggg aacgcacuaa ccucaccuac      360

cgcaucagaa auuacacacc ccaacucuca gaagccgaag ucgaaagagc gauuaaagac      420

gcauucgaac uaugguccgu cgccagcccc cuaaucuuca cccgcaucuc ccaaggugaa      480

gccgacauca acauagcauu cuaccaacgc gaccacggug acaacucccc auucgacggc      540

ccaaacggca uacuugccca cgcauuccaa cccggucaag gaaucggagg cgacgcccac      600

uucgacgccg aagaaaccug gaccaacaca uccgcaaacu acaaccuauu ccucguugcc      660

gcccacgagu ucggccacuc ccuaggcuua gcacacuccu ccgauccagg ugcccuaaug      720

uauccaaacu acgccuuccg cgaaaccucc aauuacuccc uaccccaaga ugacaucgac      780

ggaauccaag caaucuacgg acucucaucc aaccccaucc aacccaccgg uccaucaacc      840

ccaaaacccu gcgaccccuc ccucaccuuc gacgcaauca ccacucucag aggugaaauc      900

cucuucuuca aagaccguua cuucuggcga agacacccac aacuccaacg cgucgaaaug      960

aacuuuauuu cacucuucug gcccucgcuu cccaccggca uccaggccgc auacgaagac     1020

uucgaccgcg accuaaucuu ccucuucaaa gguaaccaau acugggcacu aucaggcuac     1080

gacauccuuc aaggcuaccc caaagacaua uccaacuacg gcuucccauc cuccguccag     1140

gcaaucgacg cugcagucuu cuauagaucc aaaaccuacu ucuucgucaa cgaccaauuc     1200

uggcgauacg acaaccaacg acaauucaug gaacccggcu accccaaauc aaucuccggc     1260

gcuuuccccg gcaucgaauc caaagucgac gccguuuucc aacaagaaca cuucuuccac     1320

gucuucuccg ggccacgaua cuacgccuuc gaccucaucg cccaacgcgu cacccgagua     1380

gcacgcggca acaaauggcu uaacugccgu uacggcugag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2199
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt8)

<400>  2199
gggagaaagc uuaccauguc ccucuggcaa ccccuaguuc uaguccuccu cguacuugga       60

ugcugcuucg cagcaccccg acaacgccaa uccacccuag uccucuuccc uggcgaucuu      120

cgaacaaacc ugaccgaccg ccaacucgcg gaagaauauc ucuaccgcua cggcuacaca      180

cguguagccg aaaugcgcgg agaauccaaa agccuagguc cagcacuccu ccuccuccaa      240

aaacaacuuu cacuccccga aacgggcgaa cucgacuccg ccacccucaa agcaaugaga      300

acaccacgcu gcgggguacc cgacuuaggg agauuccaaa cguucgaagg agaccuaaag      360

uggcaccacc acaacauaac uuacuggaua caaaacuaca gcgaggaccu gccccgagca      420

gucaucgacg acgccuucgc aagagccuuc gcccuaugga gcgccguaac accccucacc      480

uucacccgug uauacucccg agacgccgac auugucaucc aauucggcgu agccgaacac      540

ggagacggcu acccauucga cggcaaagac ggccuauugg cacacgcauu uccacccggc      600

ccaggaauac aaggcgacgc ccacuuugac gaugacgaac ucuggagccu gggaaaagga      660

gucguagucc ccaccagauu cggcaacgca gacggagcag caugccacuu ccccuuuaua      720

uucgaaggcc gcucuuacag cgccugcacu accgauggcc gcuccgaugg ucuacccugg      780

ugcuccacca ccgccaacua cgacaccgau gaucgcuucg guuucugucc aucugaaaga      840

cucuacaccc aggacggcaa cgccgacggc aaacccugcc aauuuccauu caucuuccaa      900

ggccaaucuu acuccgcaug caccacagac ggccgauccg auggauaucg cuggugcgcc      960

acaacugcca auuacgaccg agacaaacuc uucggauucu gcccaacccg agcagacuca     1020

accguaaugg gaggaaacuc agccggcgaa uuaugcguau uucccuucac cuuccucgga     1080

aaagaguacu ccacgugcac cagcgaaggc cgaggagacg gacgacuaug gugcgccacc     1140

acaucaaacu ucgacuccga caagaaaugg ggcuucugcc ccgaucaagg cuacucucug     1200

uucuuagucg ccgcacacga guucggacac gcccugggac uagaccacag uucagucccc     1260

gaagcgcuca uguaccccau guaccgcuuc acagaaggac caccacuaca caaggacgac     1320

guaaacggca ucagacaccu auaugguccc cgaccagaac ccgaaccacg cccucccacu     1380

accacuaccc cacaaccaac ugccccaccc acaguauguc caacaggacc acccaccgua     1440

caccccuccg aacgccccac cgccggcccu accggaccuc ccuccgcagg ucccacagga     1500

ccacccacag ccggccccuc caccgccacc acaguucccu uauccccugu cgacgacgca     1560

ugcaacguca acauauucga cgcuaucgcc gaaaucggca aucaacuaua ccuguucaag     1620

gacggcaaau auuggcgcuu cucagaaggc cgaggcagcc gcccucaagg uccauuccuc     1680

auugccgaca aauggcccgc ccuccccaga aaacuugacu ccgucuucga agaacgucuc     1740

uccaagaaau uauucuucuu cucaggccgu caagucuggg ucuacaccgg cgccagcguc     1800

cucggcccca gacgucuaga caaacuugga cucggagccg acgucgcuca gguaaccggg     1860

gcucugcgau ccggacgcgg gaagauguug cuauucagcg gacgcagacu auggcgcuuc     1920

gacgucaaag cccaaauggu cgacccgaga uccgccuccg aaguugaccg uauguuccca     1980

ggcgugcccc ucgacaccca cgacguauuc caauaccgcg aaaaagcaua cuucugccag     2040

gaccgcuuuu auuggcgagu cucuucccga ucugaacuua accaagucga ccaaguagga     2100

uaugucaccu acgacauccu ccagugcccc gaggacuaag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  2200
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt8)

<400>  2200
gggagaaagc uuaccaugca cccaggcguc cucgcagcuu uccucuuccu cuccuggaca       60

cacugccgcg cauuaccccu ccccucagga ggcgacgaag acgaccucuc cgaagaggac      120

cuccaauucg ccgaacguua ccuccgcucc uacuaccacc cgacaaaccu cgcaggaaua      180

cucaaggaaa acgccgccuc cuccaugacc gaacgccuua gagaaaugca gucauucuuc      240

ggccuagaag uaaccggaaa acuagacgac aacacccuag acgucaugaa aaaaccccga      300

ugcggugucc ccgacgucgg cgaauacaac gucuuccccc gcacccuuaa gugguccaaa      360

augaaccuga ccuaucgcau agucaacuac acgccagaca ugacccauuc cgaagucgaa      420

aaagcauuca aaaaagcguu caaaguaugg uccgacguca ccccacuuaa cuucacacgc      480

cuccacgacg gaaucgcaga caucaugaua agcuucggua ucaaagaaca cggcgacuuc      540

uaccccuucg acggcccauc aggccuacua gcccacgcau ucccccccgg cccgaauuac      600

ggcggcgacg cccacuuuga cgaugacgaa accuggacau ccuccuccaa agguuacaac      660

cuauuccuag uagccgcaca cgaauucggc cacucccucg ggcuagacca cuccaaagac      720

cccggagccc ucauguuccc cauauacacu uacaccggca aaucccacuu caugcuaccc      780

gacgacgacg uacaaggcau ccaaucccug uacggcccag gcgacgaaga cccaaacccc      840

aaacacccca aaacucccga caaaugcgac cccucccucu cccuagacgc caucaccuca      900

cuccgcggcg aaacaaugau auucaaagac cguuucuucu ggcgccucca cccacaacaa      960

guagaugcag aacucuuccu aacaaaaucc uucuggcccg aacuaccaaa ccgaaucgac     1020

gcugcauaug aacauccauc ccacgaccuc auuuucauau uucgaggccg aaaauucugg     1080

gcacuaaacg guuacgacau ccucgaaggc uaccccaaaa aaaucuccga acuaggccuu     1140

cccaaagaag uaaaaaaaau cucagccgcc guccacuuug aagacaccgg aaagacucua     1200

cuauucucag gcaaccaagu cuggcgauac gacgacacca accacauaau ggacaaagac     1260

uaccccaggc uaauagaaga agacuuucca ggcaucggag acaaaguaga cgccguauac     1320

gagaaaaacg gcuacaucua cuucuucaac ggccccauac aauucgagua cuccaucugg     1380

uccaaucgaa ucguacgcgu caugcccgcc aacucaaucc ucuggugcua aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2201
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt8)

<400>  2201
gggagaaagc uuaccaugga gacccccaac accacagaag acuacgacac caccaccgaa       60

uucgacuacg gugacgccac ccccugucaa aaagucaaug aacgcgccuu cggcgcacaa      120

cuacuaccgc cccucuacuc gcucguuuuc guaaucggcc ucgucggaaa uauacucguc      180

guccucgucc uaguccaaua caaacgccuc aaaaacauga cuucaaucua ccuccuuaac      240

cuagccaucu cugaccuccu cuuccuauuc acacucccau uuuggaucga uuacaaacuc      300

aaagacgacu gggucuucgg cgacgcaaug ugcaaaaucc uaucaggcuu cuacuacacc      360

ggccuauaua gcgaaaucuu cuucauuauc cuucucacca ucgaccgcua ccucgccaua      420

guccacgcag ucuucgccuu gcgcgcacgc accguaacuu uuggagucau aaccuccauc      480

aucauuuggg cucucgccau ccucgccuca augcccggcc uauacuucuc caaaacacaa      540

ugggaauuca cccaccauac uugcucccuc cacuucccac acgagucccu aagagaaugg      600

aaacucuuuc aagcacucaa auuaaaccuc uuuggucucg uucuuccccu ccucgucaug      660

auaauuugcu acaccggcau caucaaaauc cuccuccgcc guccaaacga aaaaaaaucc      720

aaagccgucc gccuaaucuu cguaauaaug aucaucuucu uccucuucug gacccccuac      780

aaccucacaa uccucaucuc cgucuuccaa gauuuccucu ucacccacga augcgaacaa      840

ucucgucacc ucgaccucgc uguccaaguc acagaaguca ucgcuuacac acacugcugc      900

gucaaccccg uaaucuacgc auucgucggu gaacgauucc gcaaauaccu ccgccaacuc      960

uuccaccgcc gcguagccgu ccaccucguc aaauggcuuc ccuuccucuc cgucgaccga     1020

cucgaacgcg uaucuagcac cuccccuucc acaggagaac acgaacucuc cgccggcuuc     1080

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  2202
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt8)

<400>  2202
gggagaaagc uuaccaugcg cacccucgcc ugccuccucc uccucggcug cggcuaccuc       60

gcccacgucc ucgccgaaga agccgagauc ccacgcgaag uaaucgaacg ccucgcccgc      120

ucccaaauac acuccauccg cgaccuccaa cgccuccucg aaaucgacuc aguaggcucc      180

gaggacucac ucgacaccuc acuccgcgcc cacggcgucc acgccaccaa acacgucccc      240

gaaaaaagac cacucccaau ccgacgaaaa cgauccaucg aagaagccgu ccccgcaguc      300

ugcaaaaccc gcaccgucau auacgaaauc ccacgauccc aagucgaccc caccuccgcc      360

aacuuccuaa ucuggccccc augcgucgaa gucaaacgau gcaccggcug cugcaacaca      420

uccuccguaa aaugccaacc cagccgcguc caccaccgcu ccguaaaagu agcaaaaguc      480

gaauacguac gcaaaaaacc caaacuaaaa gaaguccaag uccgccucga agaacaccua      540

gaaugcgcau gcgcaacaac aucccuaaac cccgacuacc gcgaagaaga caccggccga      600

ccacgagaau ccggcaaaaa acgcaaacgc aaacgccuca aaccaacaua aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  2203
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt8)

<400>  2203
gggagaaagc uuaccaugaa ccgaugcugg gcacucuucc uaucccucug cugcuaccua       60

cgccuagucu cagccgaagg cgaccccauc cccgaagaac ucuacgaaau gcucagcgac      120

cacuccaucc gaagcuucga cgaccuucaa cgccuacucc acggcgaccc cggcgaagaa      180

gacggagccg aacucgaccu aaacaugacc cgcucccacu ccggcggaga acucgaauca      240

cucgcacgcg gacgcagauc ccucggcucc cucaccaucg ccgaaccagc caugauagca      300

gaaugcaaaa cccgaacaga agucuucgaa aucucacgcc gccucauaga ccgaaccaac      360

gccaacuucc ucgucuggcc cccaugcguc gaaguccaaa gaugcuccgg cugcugcaac      420

aaccgcaacg uccaaugccg cccaacccaa guccaacucc gcccagucca aguacgcaaa      480

aucgaaaucg uacgcaaaaa accaaucuuc aaaaaagcca ccgucacccu agaagaccac      540

cucgccugca aaugcgaaac cguagccgca gcccgacccg uaacacgcuc ucccggcggc      600

agccaagaac aacgagcaaa aacaccccaa acacgcguca caaucaggac cguccgcguc      660

cgcagacccc caaaaggcaa acaccgcaaa uucaaacaca cccacgacaa aaccgcacuc      720

aaagaaaccc uaggcgcaua aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  2204
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt8)

<400>  2204
gggagaaagc uuaccauguc ccucuucggc cuccuccucc ucaccucagc ccuagcaggc       60

caacgccaag gcacccaagc cgaauccaac cucuccucca aauuccaauu cucauccaac      120

aaagaacaaa acggcguaca agacccgcaa caugaacgca uaaucaccgu auccaccaac      180

ggcagcaucc acuccccaag guucccccau accuaccccc gcaacaccgu ccuagucugg      240

cgccuugucg ccgucgaaga aaacgucugg auccaacuga cauucgacga acgcuucggc      300

cucgaagacc ccgaagacga caucugcaaa uacgauuucg ucgaaguaga agaaccuucc      360

gauggcacca uccucggccg cuggugcgga agcggcaccg uccccggcaa acaaaucuca      420

aaaggcaacc aaauacgcau ccgauucguc uccgacgaau acuucccauc agaacccgga      480

uucugcauac acuacaacau cgucaugcca caauucaccg aagccgucuc acccuccguc      540

cuaccccccu cagcccuccc ccucgaccua cucaacaacg ccauaacagc cuuuuccacc      600

cucgaagacc ucauccgaua ccucgaacca gaacgauggc agcucgaccu agaagaccuc      660

uaccgcccca ccuggcaacu cuuaggcaaa gccuucgucu ucggccgcaa aucgcgcgua      720

guugaccuua accuccuaac cgaagaagua cgccucuaca gcugcacccc acgcaacuuc      780

uccguaucaa uccgcgaaga acucaaacgu accgacacca uauucuggcc cggaugccuc      840

cuagucaaaa gaugcggcgg aaacugcgcc ugcugccucc auaacugcaa cgaaugccaa      900

ugcguacccu ccaaaguaac caaaaaauac cacgaagucc uucaacuccg cccaaaaaca      960

ggcguacgug gccuccauaa aucacuuacc gacgucgccc ucgaacacca cgaagaaugu     1020

gacugcgucu gucgcggauc caccggagga uaaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  2205
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt8)

<400>  2205
gggagaaagc uuaccaugca ccgccucauc uucgucuaca cccuaaucug cgccaauuuc       60

ugcucaugcc gcgacaccuc ugccacaccg caaagcgcuu caaucaaagc acuccggaac      120

gccaaccugc gacgagacga ccucuaccgc cgcgacgaaa ccauccaagu caaaggaaac      180

ggcuacguac aaagcccccg auucccaaac uccuaccccc gcaaccuccu acucaccugg      240

agacuacacu cccaagaaaa cacccgaaua caacucguau ucgacaacca auucggacua      300

gaagaagcug aaaacgacau cugccgauac gacuucguag aagucgaaga cauaagcgaa      360

acauccacaa ucaucagagg ccgcuggugc ggccacaaag aaguaccacc ccgcaucaaa      420

ucccgcacaa accaaaucaa gauaaccuuc aaaucagacg acuacuucgu cgccaaaccc      480

ggauucaaaa ucuacuacuc ccuccuagaa gacuuccaac ccgccgccgc cuccgaaaca      540

aacugggaau cagucaccuc aagcaucuca gguguaucau acaacucccc cuccgucacc      600

gaccccacac ucauagcaga cgcccucgac aagaaaauag cugaauuuga caccgucgaa      660

gaccuccuca aauacuucaa ccccgaaucc uggcaagaag accucgaaaa cauguaccug      720

gauacaccac gcuacagagg ccgaucauac cacgaccgaa aaaguaaagu cgaccuugac      780

cgccucaacg acgacgccaa acgcuauagc ugcaccccuc gaaacuacuc cgucaacauc      840

cgagaagaac uaaaacucgc aaacgucgua uucuucccac guugccuccu uguccagcga      900

ugcggaggca acugcggcug cggcaccguc aacuggcgga gcugcacaug caacuccggc      960

aaaaccguaa agaaauacca cgaaguacuc caauucgaac caggucacau caaacgucgc     1020

ggcagagcua aaaccauggc auuagucgac auacaacuag accaccacga acgaugcgac     1080

ugcaucugca gcucacgacc cccacgcuaa ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  2206
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt8)

<400>  2206
gggagaaagc uuaccauggu cacacacucc aaauuccccg ccgccggcau gucccgaccc       60

uuagacaccu ccuuacgccu aaaaaccuuc uccuccaaau ccgaauacca acucguaguc      120

aacgcaguac gcaaacucca agaauccgga uucuacuggu cagccguaac cggcggcgaa      180

gccaaccucc uccuauccgc cgaaccagcc ggcaccuucc uaauucgcga cucauccgac      240

caacgccacu ucuucacccu cuccgucaaa acccaauccg gcacaaaaaa ccuccgcauc      300

caaugcgaag gcggaucauu cuccuuacaa uccgaccccc gcuccaccca accagucccc      360

cgauucgacu gcguacucaa acucguccac cacuacaugc caccccccgg cgcccccucc      420

uucccuucac cccccaccga acccuccucc gaagucccug aacaacccuc agcccaaccc      480

uuacccggcu cccccccacg ccgcgcauac uacaucuacu caggcggcga aaaaauccca      540

cucguccucu cccgcccccu cuccuccaau guagccacac uccaacaccu cugccgcaaa      600

accgucaacg gccaccuaga cuccuacgaa aaaguaaccc aacuccccgg acccauacgc      660

gaauuccuag accaauacga cgccccacua uaaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  2207
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt8)

<400>  2207
gggagaaagc uuaccauggu ccccuccgcc ggccaacucg cccucuucgc ccucggcaua       60

guacucgcag ccugccaagc ccuagaaaac ucuaccuccc cccucuccgc cgacccccca      120

guagcagccg ccgucgucuc acacuucaau gacugcccag acucccacac ccaauucugc      180

uuccacggca ccugccgcuu ccucguacaa gaagacaaac ccgccugcgu augccauucc      240

ggauaugucg gcgcccgcug cgaacacgcc gaccuccuag caguagucgc agcaucacaa      300

aaaaaacaag caaucacagc acuugucguc gucucaaucg ucgcccucgc cguacuaauc      360

aucaccugcg uccucaucca cugcugccaa guccgaaaac acugcgaaug gugccgagca      420

cucaucugcc gccacgaaaa acccucagcc cuacucaaag gccgaaccgc augcugccac      480

uccgaaacag ucgucuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  2208
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt8)

<400>  2208
gggagaaagc uuaccaugcc uccauccggc cuacgacuac uccccuuacu ccuaccccuc       60

cuauggcucc uaguccuaac acccggccgc cccgcagccg gccuaucgac cugcaaaacc      120

aucgacaugg aacucgucaa acgcaaacgc aucgaagcca uucgaggaca aauccuaucc      180

aaacucagac ucgccucacc ucccucccag ggcgaaguac cacccggccc ccuucccgaa      240

gcaguccucg cccucuacaa cucaacaaga gaccgcgucg ccggcgaauc cgccgaaccc      300

gaacccgaac ccgaagccga cuacuacgcc aaagaaguua cccgagugcu aauggucgaa      360

acccacaacg aaaucuacga caaauucaag cagucaacac acucaauaua cauguucuuu      420

aauaccucag aacuccgcga agcaguaccu gaacccgucc uccuaucccg cgccgaacuc      480

cgacuucuca gacucaaacu uaaggucgaa caacacgucg aacucuacca aaaauacucc      540

aauaauucau ggcgcuaccu cuccaaucga cuccuugccc ccuccgacuc acccgaaugg      600

cucuccuucg acgucaccgg agucguacgc caguggcucu cccgcggcgg cgaaaucgaa      660

ggcuuccgcc ucuccgcaca cugcuccugu gacucccgcg acaauacccu acaagucgac      720

aucaacggcu ucaccaccgg ccgacgcggc gaucucgcca ccauccacgg caugaaccgc      780

ccauuccucc uccuaauggc cacaccccuc gaacgugccc aacaucugca aucaucccgc      840

caccgacgug cccucgacac caacuacugc uucuccucaa ccgagaaaaa uugcugcgua      900

cgacaacuau acaucgacuu ccgcaaagac cucggaugga aguggaucca cgaacccaaa      960

ggauaccacg ccaacuucug ccucggcccc ugccccuaca ucuggucccu cgacacacaa     1020

uacuccaaag uucucgcccu cuacaaccaa cacaaucccg gcgcaucagc agcccccugc     1080

ugcguccccc aagcccuaga accccuccca aucgucuacu acgucggccg aaaaccaaaa     1140

gucgaacaau uauccaacau gaucguccgc agcugcaaau gcuccugagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  2209
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt8)

<400>  2209
gggagaaagc uuaccaugca cuacugcgua cucuccgcau uccucauacu ccaccucguc       60

accgucgccu uaucuuuauc cacaugcuca acccucgaca uggaccaauu caugcgcaaa      120

cgcaucgaag ccauccgagg acaaaucuua ucaaaacuca aacuaaccuc cccacccgaa      180

gacuaccccg aaccagaaga agucccaccc gaagucauuu ccauuuacaa cuccacacgc      240

gaccugcuac aagaaaaagc cucccgccgc gccgccgcau gcgaacgcga acgcucagac      300

gaagaauacu acgccaaaga agucuacaaa aucgacaugc cacccuucuu ccccuccgaa      360

aacgccaucc cacccaccuu cuacagaccc uacuuccgua ucguccgcuu ugacgucagc      420

gcaauggaga aaaacgccag uaaccuuguc aaagccgagu uccgaguauu ccgccuacaa      480

aacccaaaag cccgcguccc agaacaacgc aucgaacucu accaaauccu aaaauccaaa      540

gaccuaacuu cucccaccca acgauacaua gacucaaaag uugucaagac ccgcgcagaa      600

ggugaauggc ucagcuucga cguaacugac gccguccacg aauggcuaca ccauaaagac      660

cgaaaccuag gcuucaaaau aagccuccac ugcccaugcu gcacauucgu ccccucgaac      720

aacuauauca ucccgaacaa aucagaggaa cuggaagccc gcuucgccgg aaucgacgga      780

accuccaccu acaccuccgg cgaccagaaa accauuaaau caacccgcaa aaagaacagc      840

ggaaaaaccc cacaccuccu acucaugcua cuaccauccu accgacuaga aucacaacaa      900

accaaccgca gaaagaaacg cgcccucgau gccgccuacu gcuucaggaa cguccaagac      960

aacugcugcc uacgcccccu auacaucgac uucaaacgcg accucggaug gaaauggauc     1020

cacgaaccua aaggcuacaa cgcaaacuuc ugcgccggag caugccccua ccucuggagc     1080

uccgacacac aacacucucg cguccucucc cuauacaaca ccaucaaccc cgaagccucc     1140

gccucacccu gcugcgucuc ccaagaccuc gaaccccuca caauacuaua cuacaucggc     1200

aaaaccccca aaaucgaaca acuguccaac augaucguca aauccugcaa augcagcuag     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  2210
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt8)

<400>  2210
gggagaaagc uuaccaugaa gaugcaccuc caacgcgccc ucguaguccu cgcccuccuc       60

aacuucgcca cagucagccu cucccuauca accugcacca cccuagacuu cggccacauc      120

aaaaagaaaa gagucgaagc cauccgcggc caaauccucu ccaaacuccg ucucaccagc      180

ccacccgaac ccaccgucau gacccacguc ccauaccaag uccucgcccu auacaacucc      240

acgcgcgaac uacuagaaga aaugcacgga gaaagagaag aaggaugcac ccaagaaaac      300

acagaaucag aauacuacgc aaaagaaauc cacaaauucg acaugaucca aggacucgcc      360

gaacacaacg aacucgccgu gugccccaaa ggcaucaccu cuaaagucuu ccgauucaac      420

gucuccucag uagagaaaaa ccgcaccaac cucuucagag ccgaguuccg aguccucaga      480

guccccaacc ccucuucaaa acgcaacgaa caacgcauug aacuguucca aauccuacga      540

ccagacgaac acaucgcuaa acaacgauac auaggaggca aaaaccugcc cacccgagga      600

acagcagaau ggcucuccuu cgacgucacc gacaccgucc gcgaauggcu cuuacgccga      660

gaauccaacc uuggacuaga aaucuccaua cacugccccu gccacaccuu ccagcccaac      720

ggagacauac ucgaaaacau ccacgaaguc auggaaauca aauucaaagg aguagauaac      780

gaagacgacc acggacgcgg cgaccucggc cgacucaaga aacaaaaaga ccaccacaac      840

ccgcaccuca uacugaugau gaucccaccc caucgccucg auaaccccgg ccagggcggc      900

caacggaaga aacgagcacu cgacaccaac uauugcuuca gaaaccucga agaaaacugc      960

ugcgucagac cccucuacau cgacuuccgc caagaccuag gcuggaaaug gguacacgaa     1020

ccaaaaggcu acuacgccaa cuucugcagc ggacccugcc cauaccuccg aucggcagac     1080

accacccacu caaccguccu cggccucuac aacacccuua accccgaagc auccgcaucc     1140

cccugcugcg uaccgcaaga ccuagaaccc cucaccauac uauacuacgu cggccgaacc     1200

ccaaaagucg aacaauuauc caacaugguc gucaaauccu gcaaaugcag cuaaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2211
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt8)

<400>  2211
gggagaaagc uuaccauggc accaguagcc gucugggccg ccuuggccgu uggccuagaa       60

cucugggccg cagcccacgc ccugccagcc caagucgcau ucaccccuua cgcccccgaa      120

cccggcagca caugccgacu ccgcgaauac uacgaccaaa cggcacagau gugcugcucu      180

aaaugcagcc caggccaaca cgcaaaaguc uucuguacaa aaaccagcga caccguaugc      240

gacuccugcg aagacuccac uuauacccaa cucuggaacu ggguccccga augccucucu      300

ugcggcagcc gcugcucauc cgaucaaguc gaaacccaag ccuguacccg cgaacaaaac      360

agaaucugua ccugcagacc cggcugguac ugcgcccucu ccaaacaaga aggaugccga      420

cuaugcgccc cucuccgcaa augccgccca ggauucggcg uagcacgccc cggcaccgaa      480

accucagacg ucgucugcaa accuugugcg cccggaacau ucagcaacac caccucaucc      540

accgacaucu gcagacccca ucaaauaugc aacgucgucg cuauccccgg aaacgcauca      600

auggacgcug ucugcaccuc aaccucuccc accagaucca uggcaccagg ggccguccac      660

cuaccccaac ccgucuccac ucgaucccaa cacacccaac ccacaccaga accguccacc      720

gccccaucca ccuccuuccu ccuccccaug ggcccauccc cgcccgccga agguucuacc      780

ggagacuucg cccuucccgu cggccuuauc gucgguguca ccgcacucgg acuccucauc      840

auaggcgucg ucaacugcgu caucaugaca caaguaaaga agaaaccacu uugccuacaa      900

cgagaagcca aaguacccca ccuccccgca gacaaagccc guggcaccca aggacccgag      960

caacaacacc uccuaauaac cgcccccuca uccuccuccu caucacucga aucauccgcc     1020

ucagcacucg accgcagagc gcccacccgc aaccaaccac aagcccccgg uguagaagcc     1080

uccggcgcug gcgaagcccg cgccuccaca ggaucuuccg acucuucacc cggcggccac     1140

ggcacccaag ucaacguaac cugcauaguc aacguaugcu ccuccuccga ccacuccuca     1200

caaugcaguu cccaagcauc aucaacaaug ggagacacag acuccucccc cuccgaaucc     1260

ccaaaagacg aacaaguccc auuuucaaaa gaagaaugug ccuucagauc ccaacucgaa     1320

acaccagaaa cccuacuugg cuccacagaa gaaaaacccc ucccccuagg cguucccgac     1380

gcuggcauga aaccauccua aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  2212
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt8)

<400>  2212
gggagaaagc uuaccaugcc ggucaugaga uuguucccgu gcuuucucca gcuauuggcc       60

ggguuagcac uaccggcagu gcccccacaa cagugggcgc ucucggccgg gaacgggagc      120

ucggaagugg aagugguacc auuccaggaa gugugggggc gcucguacug ucgagcgcuc      180

gagcgauugg uagaugucgu gagcgaguac ccaagcgagg uagagcacau guucucaccc      240

ucaugcguga gcuugcucag gugcacgggc uguugcgggg acgagaacuu gcacuguguc      300

ccgguagaga ccgcgaacgu gaccaugcaa cugcucaaga ucagaagcgg ggacaggccc      360

ucguacgugg aauugaccuu uagccagcac gugcgcugug aaugucgccc gcucagagaa      420

aagaugaagc ccgagcgcag acgaccgaaa gggcgcggga aaaggcgcag ggaaaagcaa      480

aggcccacgg acugucacuu gugcggggac gcggucccgc gcagguaagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  2213
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt8)

<400>  2213
gggagaaagc uuaccaugac cgaccgccag accgacaccg cgcccucgcc aucauaccau       60

cucuugcccg gacgcaggag aacagucgau gccgcggcau cgcgagggca aggaccagag      120

cccgcaccag gaggaggggu cgagggggua ggagcgcgcg gaguagcgcu caaacuguuc      180

guacaacugc uaggcugcag uagguucggg ggagcggucg uacgcgcggg ggaggccgaa      240

ccaagcggcg cggccagaag cgcaagcagc ggcagggaag aaccacagcc cgaggaagga      300

gaagaggaag aggaaaaaga agaggaaagg ggcccacagu ggcgacuggg agcgcgcaag      360

cccgggagcu ggaccggaga agcggcagug ugcgcggacu cggccccggc agcacgcgcg      420

ccacaggccc uggccagagc cucaggcagg ggcgggcgcg uggccaggcg cggggcagaa      480

gaaucaggac cgccccacag cccaagcagg cgagggagcg caaguagggc cgggcccggc      540

cgcgcgagcg aaaccaugaa cuuccuccug agcugggucc acuggucgcu cgcgcuauug      600

cucuaccucc accacgcgaa auggagccag gccgcgccca uggcagaagg aggcgggcag      660

aaccaccacg agguagugaa auucauggac guauaccaaa ggagcuacug ccaccccaua      720

gaaacgcuug uggacauauu ccaagaauac cccgacgaaa ucgaauacau auucaaaccg      780

agcugcgucc cacucaugcg cugcggaggg ugcugcaacg acgaagggcu cgaaugcgug      840

cccacggaag agagcaauau cacgaugcaa aucaugcgca uaaaaccgca ccaggggcaa      900

cacauagggg agaugucguu ccuacaacac aacaaaugcg aaugccgacc caagaaagau      960

cgagcacgcc aggaaaagaa aucagucagg ggcaaaggaa agggccagaa aagaaaaaga     1020

aagaaaagcc gguacaaaag cuggagcgua uacgugggcg cgcgaugcug ccuaaugccg     1080

uggagccuac cgggaccgca cccaugcgga cccugcagcg agagaagaaa acaccuauuc     1140

guacaggacc cgcagacaug caaaugcucg ugcaagaaca cagauucgcg augcaaagca     1200

cgacagcucg agcucaauga aaggacaugc agaugugaca aaccccgacg cuagggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2214
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt8)

<400>  2214
gggagaaagc uuaccaugaa cuuccuccuc uccugggucc acuggucccu agcccuccua       60

cuauaccucc accacgccaa auggagccaa gccgccccca uggccgaggg cggcggacaa      120

aaccaccacg aagucguaaa auucauggac guauaccaac gaagcuacug ccaccccauc      180

gaaacccucg uagacauauu ccaagaauac cccgacgaaa ucgaauacau cuucaaacca      240

agcugcguac cccuaaugcg augcggcggc ugcugcaacg acgaaggccu cgaaugcgua      300

cccaccgaag aaagcaacau cacaaugcaa aucaugagaa ucaaacccca ccaaggccaa      360

cacauaggcg aaauguccuu ccuccaacac aacaagugcg aaugccgccc caaaaaagac      420

cgcgcccgcc aagaaaagaa auccguccgu ggaaaaggca aaggccaaaa acgaaaacga      480

aaaaaaagcc gcuacaaauc cuggagcguc uacguaggcg cccgaugcug ccuaaugcca      540

uggucccucc ccggccccca ccccugcggc cccugcuccg aacgccgaaa acaccucuuc      600

guccaagacc cacaaaccug caaaugcucc ugcaaaaaca cagacucacg cugcaaagca      660

agacaacucg aacuaaacga acgcaccugc cgcugugaca aaccacgacg auaaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  2215
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt8)

<400>  2215
gggagaaagc uuaccauguc accacuacuc cgccgacuac uccucgccgc ccuccuccaa       60

cucgcccccg cccaagcccc cgucagccaa cccgacgccc caggccacca acgcaaaguc      120

gucuccugga ucgacguuua cacucgcgca acaugccaac cccgcgaagu agucguccca      180

cucaccgucg aacuaauggg caccgucgcc aaacaacucg uccccucaug cgucaccguc      240

caacgcugcg gaggaugcug ccccgacgac ggccuagaau gcgucccaac cggccaacac      300

caaguacgca ugcaaauacu caugauccga uaccccucau cccaacuagg cgagaugucc      360

cucgaagaac acucccaaug cgaaugccga cccaaaaaaa aagacuccgc cgucaaaccc      420

gaccgagccg ccacacccca ccaccgccca caaccccgcu ccgucccagg cugggacuca      480

gcccccggcg caccaucacc cgccgacauc acccacccca cacccgcacc cggccccucc      540

gcccacgccg cccccucaac caccuccgca cuaacccccg gccccgccgc cgccgccgcc      600

gacgccgccg caucaucagu agcaaaaggc ggagcauaag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  2216
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt8)

<400>  2216
gggagaaagc uuaccaugca ccuccucgga uucuucucag uagccugcuc ccuucuggcc       60

gcagcccucc uccccggccc gcgcgaagcc cccgccgccg ccgcagccuu cgaauccggc      120

cuagaccuga gcgacgccga gcccgacgca ggagaagcca ccgccuaugc cuccaaagac      180

cucgaagaac aauugcgcuc ggucucguca gucgacgaac ucaugaccgu ccucuaccca      240

gaauacugga aaauguauaa augccaacuc cgcaaaggug gcuggcaaca caaccgggaa      300

caagccaacc ucaacagccg aacagaagaa acaaucaaau ucgccgcagc ccacuacaac      360

acagaaaucc ucaaauccau agacaacgaa uggcgcaaaa cccaaugcau gccccgcgaa      420

gugugcaucg acguaggcaa agaguucggc gucgccacaa acacauucuu caaaccaccg      480

ugcgucuccg ucuaccgcug uggcggaugc ugcaacucgg aaggacuaca augcaugaac      540

acguccaccu ccuaccucuc caaaacccuc uucgaaauaa ccguaccacu aucccagggu      600

ccaaaacccg uaacaauauc cuucgcaaac cauacuuccu gccgaugcau guccaaacuu      660

gacgucuaca gacagguaca cagcauaauc cggcguuccc uacccgcuac ccuaccacaa      720

ugccaagcag ccaauaaaac cuguccaaca aacuacaugu ggaacaacca caucugucgc      780

ugccucgccc aagaagacuu cauguucucc ucagacgccg gcgacgacuc aacagacggc      840

uuccacgaca ucuguggccc aaacaaagaa cuugaugaag aaacaugcca augcgucugc      900

cgagccggac uccgacccgc aagcugcggc ccccauaaag aacuagaccg gaacucaugc      960

caaugcguau guaaaaauaa acuauucccc ucccaaugcg gcgccaaccg ggaguucgac     1020

gaaaauaccu gccaaugcgu augcaaacgc acuugcccac gcaaccaacc ccuaaacccc     1080

ggcaaaugcg ccugcgaaug caccgaaucg ccccaaaaau gccuacucaa aggcaagaaa     1140

uuccaccacc aaaccugcuc cuguuaccgc cgacccugca ccaaccgcca aaaagccugc     1200

gaacccgguu ucucauacuc agaagagguc ugccgaugcg uccccagcua uuggaaacgc     1260

ccacaaaugu ccuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  2217
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt8)

<400>  2217
gggagaaagc uuaccaugua ccgugaaugg gucgucguca acguauucau gaugcuauac       60

guucaacucg uccaaggauc cucaaaugaa cacggcccag ucaaacgcag cucccaaucc      120

acacucgaac gcuccgaaca acaaauccgc gccgccuccu cccucgaaga acuacuucgc      180

aucacccauu cagaagacug gaaacuaugg cgaugccgcc uccgccucaa aucauuuacc      240

ucaauggaca gccgcucagc cucccaccgc uccacacgcu ucgcggccac uuuuuacgac      300

auagaaaccu uaaaagucau agaugaagaa uggcaacgca cacaaugcuc ccccagagaa      360

accugcgucg aagucgccuc cgaacucggc aaaucaacca acaccuucuu caaaccccca      420

ugcgucaacg uauuccguug cggaggcugc ugcaacgagg aaucauuaau cugcaugaac      480

acaagcacau ccuacaucuc caaacaacuc uucgaaaucu cuguaccccu caccuccguc      540

cccgaauuag uaccugucaa agucgcaaac cacacaggau gcaagugccu cccuaccgca      600

ccccgccacc ccuacuccau aauccggcga uccauccaaa uccccgaaga agaccgaugc      660

ucacacucaa agaaacucug ccccaucgac augcucuggg acuccaacaa augcaaaugc      720

guccuccaag aagaaaaccc ccuagccggc accgaggacc acucccaccu acaagaacca      780

gcccucugcg gcccccacau gauguucgac gaagaccgau gcgaaugcgu cugcaaaacc      840

cccugcccca aagaccucau ccaacacccc aaaaacugcu ccugcuucga augcaaagaa      900

ucccuagaaa ccugcugcca aaaacacaaa cuauuccacc cagauaccug cucaugcgaa      960

gaccgcugcc ccuuccacac acgccccugc gccuccggca aaaccgccug cgccaaacac     1020

ugccgauucc ccaaagaaaa acgcgccgcc caaggacccc acucccgcaa aaaccccuaa     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  2218
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt9)

<400>  2218
gggagaaagc uuaccaugga cuccgacgaa accggcuucg aacacuccgg ccucuggguc       60

uccguccucg ccggccuccu ccuaggcgcc ugccaagcac accccauacc cgauucuucc      120

ccacuacucc aauucggcgg ccaaguccgc caacgcuacc ucuacacaga cgacgcccaa      180

caaacagaag cccaccuaga aauccgagaa gacggcacag ucggaggcgc cgccgaccaa      240

ucacccgaau cccuccuaca acuaaaagcc cucaaacccg gcgucaucca aauccucggc      300

gucaaaacca gccgauuccu cugccaacgc cccgacggcg cccucuacgg aucccuacac      360

uucgacccag aagccugcuc cuuccgcgaa cuccuccuag aagacggcua caacgucuac      420

caaucagaag cccacggccu cccccuccac cuccccggca acaaaucacc acaccgcgac      480

ccagccccac gcggccccgc ccgcuuccuu ccccuccccg gccucccacc cgcacucccc      540

gaacccccag gcauccucgc accccaaccc ccagacgucg gcuccucaga cccccucucc      600

auggucggcc ccucucaagg cagaucccca uccuacgccu ccuaaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  2219
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt9)

<400>  2219
gggagaaagc uuaccaugca cuccuucccu ccccuccuac uacuccucuu cuggggcguu       60

gucucccacu ccuuccccgc gacccuagaa acacaggaac aagacguuga ccucguccaa      120

aaauaccuag aaaaauacua caaccucaaa aacgacggac gccaaguaga aaaacgacgc      180

aacuccggcc ccgucgucga aaaacucaaa cagaugcaag aguucuucgg ccucaagguc      240

accggcaaac ccgacgccga aacacuaaaa guaaugaaac aaccccgcug cggcguaccc      300

gacgucgccc aauucguacu caccgaaggu aacccacgcu gggaacaaac ccaccucacu      360

uaccggaucg aaaacuacac ccccgaccuc ccccgcgccg acgucgacca ugccaucgaa      420

aaagccuucc aacucugguc aaacgucaca ccccucaccu ucaccaaagu cucugaaggc      480

caagcagaca ucaugauauc auucguacga ggcgaccacc gagacaacuc ccccuucgac      540

ggcccgggag gcaaccuggc acacgccuuc caaccagguc caggaaucgg cggcgacgca      600

cacuuugacg aggacgagcg auggaccaac aacuuccgag aauacaaccu ccaccgcguc      660

gcagcccacg agcucggcca cucacuggga cucucacacu ccaccgauau cggagcacuc      720

auguaucccu cuuacacuuu cuccggcgac guacaacuag cccaagacga cauagacgga      780

auccaagcaa ucuacggacg cucccagaac cccguccagc ccaucggacc ucaaacacca      840

aaagccugcg acuccaaacu aacauucgac gccaucacaa ccauacgagg cgaagucaug      900

uucuucaaag acagauucua caugcgcaca aacccuuucu aucccgaagu cgagcucaac      960

uucaucuccg ucuucuggcc ccaacucccc aacggccuug aagcagccua cgaguucgcc     1020

gaccgcgacg aaguccgauu cuucaaagga aacaaauacu gggccgucca aggccaaaac     1080

guccuacaug gcuaccccaa agacauauac uccuccuucg gcuucccaag aaccgucaaa     1140

cacaucgacg cagcacucuc cgaggaaaac accggaaaaa ccuacuucuu cgucgcaaac     1200

aaauacuggc gcuacgacga auacaagcgc ucaauggacc ccggcuaucc aaaaaugauc     1260

gcacacgacu uccccggcau cggucacaaa gucgaugcug uuuucaugaa agacggcuuc     1320

uucuacuucu uccacggaac ccgccaauac aaauuugacc caaaaaccaa acgcauccuc     1380

acacuacaaa aagccaacag cugguucaac ugccgcaaaa acuaaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  2220
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt9)

<400>  2220
gggagaaagc uuaccaugca cuccuuccca ccccuacucc uccuacucuu cuggggcgua       60

gucucccacu cauucguacu caccgaaggc aacccccgau gggaacaaac ccaccucacc      120

uaccgcauag aaaacuacac ccccgaccuc ccccgcgccg acguagacca cgccaucgaa      180

aaagccuucc aacucugguc caacguaaca ccccucaccu ucaccaaagu cuccgaaggc      240

caagcagaca uaaugauauc auucguccgc ggcgaccacc gagacaacuc acccuucgac      300

ggccccggcg gcaacuuagc ccacgccuuc cagcccggcc caggcauagg cggagacgca      360

cacuucgaug aagacgaacg cuggaccaac aacuuccgcg aauacaaccu ccaccgcguc      420

gcagcccacg aacucggcca cucccuugga cucucacacu ccaccgacau cggagcccua      480

auguacccau cauacacauu cucaggcgac guacaacucg cccaagacga caucgacggc      540

auacaagcaa ucuauggccg cucacagaac ccaguacaac caaucggccc ccaaaccccc      600

aaagccugcg acuccaaacu caccuucgac gcaauaacca caauucgagg agaagucaug      660

uucuucaaag accgauucua caugcgcacc aaccccuucu accccgaagu agaacucaac      720

uucauauccg ucuucuggcc ucaacuaccc aacggccucg aagcagcaua cgaguucgcc      780

gaccgagacg aaguccgauu cuucaaaggc aacaaauacu gggccgucca aggccaaaac      840

guccuacacg gcuacccaaa agacaucuac ucuuccuucg gcuucccacg aacaguaaaa      900

cacauagacg cagcucucuc agaagaaaac accggcaaaa cuuacuucuu cguagcaaac      960

aaauacuggc gcuacgacga auacaaacgc ucuauggacc ccggauaccc caaaaugaua     1020

gcucacgacu uccccggcau aggucacaaa gucgacgcag uauucaugaa agacggcuuc     1080

uucuacuucu uccacggcac ccgccaauac aaauuugacc ccaaaaccaa acgcauccuc     1140

acccuucaaa aagccaacuc cugguuuaac ugucgcaaaa acuaaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  2221
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt9)

<400>  2221
gggagaaagc uuaccaugaa aaagaacauc cuaaagauac ucauggacag cuacagcaaa       60

gaaucgaaaa uccaaaccgu ucgucgagua accuccguaa gccuccuagc cguauaucug      120

accaugaaca cgagcagccu cguacuagcc aaacccauag aaaacaccaa cgauaccuca      180

aucaaaaacg uagaaaaacu gaggaacgca cccaaugaag aaaacucaaa gaaaguugaa      240

gacagcaaaa augacaaggu cgaacacguc aaaaacaucg aagaagcaaa aguagagcaa      300

guagcccccg agguaaaaag caaaagcacg cucagaucag caagcauugc caacacaaac      360

agcgaaaaau acgacuucga auaccuaaac ggucuaagcu auaccgaacu gacgaacuua      420

auaaagaaca ucaaauggaa ccaaauaaac ggccuauuca acuacuccac aggcagccaa      480

aaauucuucg gggacaaaaa cagaguacag gcaauaauca acgcgcucca ggaauccggc      540

cguaccuaca cggcgaacga caugaagggg aucgaaacau ucaccgaagu acuccgugcc      600

ggcuucuacc uuggguauua caaugacgga cucagcuacc ucaacgaccg caacuuucag      660

gacaagugca uccccgcaau gaucgcaauc caaaagaacc cuaauuucaa auuaggaaca      720

gccguacagg acgagguaau cacgagccug ggcaaauuaa ucggcaacgc cucugcgaac      780

gcagaggucg ucaacaacug ugugccaguc cucaagcagu uccgggagaa ccugaaucaa      840

uacgcacccg acuacguaaa gggcacugcc gucaacgaac ucauaaaagg cauagaguuc      900

gacuucucag gcgccgccua cgaaaaagac guuaaaacga ugcccuggua cggaaaaaua      960

gaccccuuca uaaacgaauu aaaagccuua ggccucuacg gcaacaucac cagcgcaacg     1020

gaaugggccu cagacguagg uaucuacuau cuuuccaaau ucggauuaua cagcaccaac     1080

cgcaacgaca uaguacaauc ccuagagaaa gccgucgaua uguacaaaua cggaaaaaua     1140

gcguucguag ccauggaacg aaucaccugg gacuacgacg gcaucggcuc aaacggcaag     1200

aaagucgacc acgacaaauu ccuggacgac gccgaaaaac acuaucuccc caaaaccuac     1260

acauucgaca acgggacguu cauaauccgc gcgggcgaca aaguauccga agagaaaauc     1320

aaacgccuau acugggccuc cagagaaguu aaaagccaau uucaccgggu gguggggaac     1380

gacaaagccc uagaagucgg aaacgccgau gacguccuca caaugaaaau cuucaauagu     1440

cccgaagaau acaaauucaa caccaacaua aacggcguua gcaccgacaa ugggggccug     1500

uacaucgaac cccggggcac auucuacacc uacgaaagaa cgccucaaca aucuaucuuc     1560

agucuggagg aguuguuccg ccacgaauac acccacuacc uacaagcacg uuaccucguc     1620

gacggccuau ggggccaggg acccuuuuac gaaaagaaca ggcuaaccug guucgacgag     1680

ggcacagccg aguucuucgc cgggagcacc cgcacauccg gaguacugcc caggaaaagc     1740

auccucggcu accuugccaa agauaaaguu gaccaucgcu acucacugaa gaagacccuu     1800

aacagcggau augacgauag cgacuggaug uucuacaacu auggguucgc gguagcacac     1860

uaccuauaug aaaaagacau gcccacuuuc aucaaaauga auaaggcaau ccucaacacc     1920

gacgucaaau ccuacgacga aaucauuaag aaacugagcg acgacgcaaa caagaacacc     1980

gaguaccaga accacaucca ggagcuagcc gacaaguacc agggggcagg aaucccccua     2040

guaucagacg acuaccucaa agaucacggc uacaagaaag cgagcgaagu auacuccgaa     2100

auaucgaagg cagcaagccu cacgaacaca agcgugacag ccgaaaaauc acaauacuuc     2160

aacaccuuca cucuccgggg uaccuacaca ggcgagaccu ccaagggaga auuuaaagac     2220

ugggacgaaa ugagcaaaaa gcucgacggc acccucgaau cacucgccaa aaacuccugg     2280

uccggcuaca agacauuaac ugcauacuuc acuaauuacc gcgucaccag cgacaacaaa     2340

guccaauacg acgucguuuu ccacggggua cuaaccgaua acgcagacau cuccaacaac     2400

aaagcaccua ucgcaaaagu cacgggacca uccacugggg ccguuggacg caauauugag     2460

uucucaggua aagacagcaa agacgaggac ggcaaaaucg ucagcuacga cugggauuuc     2520

ggagacggcg cgacaucacg aggcaaaaac agcguccacg cauauaagaa agccggcacc     2580

uacaacguua cacuaaaggu cacagacgac aaaggagcaa cagcgacaga gucauucaca     2640

auagagauca aaaacgagga cacgacgaca ccuaucacaa aagaaaugga accgaacgac     2700

gacaucaaag aagccaacgg cccaauaguc gaaggaguaa ccguuaaagg cgaccucaac     2760

ggcucagaug acgccgauac cuucuacuuc gacgucaagg aagacgggga cguaacaauu     2820

gaacuaccau acucaggguc aagcaauuuc acauggcucg ucuacaaaga aggcgacgau     2880

cagaaccaua uagcaucagg cauagacaaa aacaacucga aagugggcac cuuuaaaagc     2940

acaaaaggcc gccacuacgu guucauauac aaacacgaca gcgccucgaa caucucuuac     3000

ucacuaaaca ucaagggccu aggaaacgag aagcugaaag aaaaagaaaa caacgacucu     3060

ucagauaagg ccaccgucau ucccaacuuc aacacaacaa ugcaaggcuc gcugcucggc     3120

gacgacucca gagacuauua cuccuucgag guaaaagaag aaggagaagu caacaucgaa     3180

uuggacaaga aagacgaguu cggggugaca uggacccuuc acccggaauc caacauaaac     3240

gacaggauaa ccuacgggca aguagaugga aacaaagugu cgaacaaagu caagcuccga     3300

cccggcaaau acuacuugcu agucuacaaa uacagcggcu cuggcaacua cgaacuacga     3360

guaaacaaau agggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  2222
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt9)

<400>  2222
gggagaaagc uuaccaugaa augggugacu uucauuuccc ugcuguuccu cuucagcagc       60

gccuacucca ucgcaaacac aaacagcgaa aaauacgacu ucgaauaccu gaacggacuc      120

aguuacaccg aacucacaaa ccucaucaag aacaucaagu ggaaccaaau aaacggccuc      180

uucaacuacu cgaccggcuc ccaaaaguuc uucggggaua agaaccgcgu ccaagccauu      240

aucaacgccc uccaagaaag cgggcgcaca uacaccgcca acgacaugaa gggcauagaa      300

acauuuacag aagugcuacg cgcgggcuuc uaccucggcu auuacaacga cggacucagc      360

uaccuaaacg accgaaacuu ccaggacaag ugcauaccgg caaugauagc cauccagaaa      420

aaucccaacu uuaaacucgg aacugccgug caagacgaag uaaucaccuc gcucggaaaa      480

cuaaucggca acgccucagc caaugccgaa guagucaaua acugcguccc cgucuuaaag      540

caauuccgag agaacuugaa ccaauacgca ccagacuacg ucaagggcac cgccguaaac      600

gaguuaauca aagggauaga guucgacuuc ucgggagccg cauaugaaaa agacgucaaa      660

accaugccau gguacggcaa aaucgacccc uucauaaacg aacucaaagc ccuuggccua      720

uacggcaaca uaacaagcgc gacagaaugg gccagcgacg uaggcaucua cuaccuauca      780

aaguucggac ucuacagcac caaccggaac gacauagucc aaagccucga aaaagcagua      840

gacauguaca aauacggcaa aauagccuuc gucgcaaugg agcgcauaac augggauuac      900

gacgggaucg gcaguaaugg uaagaaagua gaccaugaca aguuccucga cgacgcagaa      960

aaacacuacc uaccuaagac auacaccuuc gacaacggaa ccuucauaau ccgcgcaggc     1020

gacaaaguua gugaggagaa aaucaaaaga cuauacuggg caucaagaga agucaaauca     1080

caauuccacc gcguagucgg caacgacaaa gcccucgaag uggggaacgc cgacgacguc     1140

cuaacaauga aaaucuucaa cagccccgaa gaauacaaau ucaauacuaa uauaaacgga     1200

guaagcacag acaacggcgg ccuauauauc gaaccccgcg ggacuuucua uaccuacgaa     1260

aggacgccgc aacaauccau auucucacua gaagaacuau uccgccacga auacacccac     1320

uaccuccagg caagauaccu agucgacggc cuaugggguc agggcccauu cuacgaaaag     1380

aaccgccuaa ccugguucga cgagggaaca gccgaauuuu ucgccggauc cacccgcaca     1440

agcggagucc ugccccgcaa aucaauacuc ggguaccuag cgaaagacaa aguggaccac     1500

cgauacagcc uaaagaaaac acucaacucc ggauacgaug acagcgacug gauguucuac     1560

aacuacggau ucgccgucgc acacuaccua uacgagaaag acaugcccac uuucaucaaa     1620

augaacaaag cgauacucaa caccgacguc aaaagcuacg acgagaucau caagaaacug     1680

uccgacgacg caaauaaaaa caccgaauac cagaaccaca uucaggaacu cgccgacaaa     1740

uaccaaggag ccggcauccc acucgucagc gacgacuacc ucaaagacca cggguacaaa     1800

aaggcguccg aaguauauuc ugagaucagc aaagccgcau cccugaccaa cacaucaguc     1860

acagcagaga aaucucagua cuucaacaca uucacgcucc gggggaccua cacaggcgaa     1920

acuagcaaag gggaguucaa ggacugggac gagaugagca agaaacugga uggcacacuc     1980

gagagucucg cgaaaaacuc cuggucgggc uacaaaacgc uuacagcaua uuucaccaac     2040

uaccgcguca ccucagacaa caaaguccaa uacgacgucg uguuccacgg agugcucacc     2100

gacaacgccg acaucuccaa caacaaggca ccuaucgcaa aggugaccgg ccccucaaca     2160

ggcgcgguug gacggaacau cgaguucucc gggaaagaca guaaggacga ggacggcaaa     2220

auaguaagcu acgacuggga cuucggagac ggggcgaccu cccgaggcaa gaacagcguc     2280

cacgccuaca agaaagccgg cacauacaac gugacacuua aaguuaccga cgacaaagga     2340

gccaccgcca cggaguccuu uaccaucgag aucaaaaacg aagacaccac aaccccaaua     2400

accaaagaaa uggaaccuaa cgacgacauu aaggaggcaa acggcccaau aguagaagga     2460

guuacgguca agggugaccu caacgguucc gaugacgcag acaccuucua cuucgacguc     2520

aaagaagacg gggauguaac caucgaacua cccuacuccg gauccucaaa uuucacuugg     2580

cuaguauaca aggagggcga cgaccaaaac cacauagccu cggggauaga caaaaacaac     2640

ucuaaaguag gaaccuuuaa guccacaaag ggacggcacu acgucuuuau cuacaagcac     2700

gacuccgcuu ccaacauauc guacucguua aacaucaaag gacuaggaaa cgaaaaacuc     2760

aaagagaaag aaaacaacga cucaucggac aaagcgacag uaauaccaaa cuucaacacc     2820

acgaugcagg gcucccuauu gggagaugac agccgagacu acuacucguu ugaaguaaaa     2880

gaggaaggcg aagucaacau cgaacuagau aagaaagacg aguucggagu uacguggacc     2940

cuccaccccg agagcaacau caaugaccga auuaccuaug gccaggucga cgguaacaaa     3000

guaucuaaua aagucaaacu ccgcccaggc aaauacuacc uccucgucua caaguacagc     3060

gguagcggca acuacgaacu acgcgugaau aaauaaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  2223
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt9)

<400>  2223
gggagaaagc uuaccaugaa gugggugaca uucaucuccc uacuguucuu auuuaguucc       60

gccuauagua ugaaaaagaa cauucucaaa auccucaugg acagcuacag caaagagagc      120

aagauccaga ccgugcgucg aguaaccagc gucagcuuac uagcgguaua ccuaaccaug      180

aacacaucca gccuaguccu ggcaaaaccc aucgaaaaca ccaaugacac uuccaucaag      240

aacgucgaga agcuacgaaa cgcaccaaac gaagagaaua gcaagaaagu ugaagauucc      300

aaaaaugaca aaguagagca cgucaaaaac aucgaagaag caaaagucga acaaguagcc      360

ccggaaguca aauccaagag cacgcuccgc uccgccagua gacggcgcag gaaacgcauc      420

gcaaacacaa acuccgagaa auacgacuuc gaauacuuga acggauuaag cuacacggag      480

cuaaccaacc ucaucaaaaa uauaaaaugg aaccaaauaa acggccuauu caacuauagc      540

accggguccc agaaauucuu cggagauaag aaccgcguac aagcuaucau caaugcccug      600

caggaauccg gccgcacaua cacggccaac gacaugaaag guauagaaac auucacagaa      660

gugcuaaggg ccggcuucua ccucggcuac uacaacgacg ggcuaucaua ccuaaaugac      720

agaaauuuuc aggacaaaug cauaccggcu augaucgcga uacagaaaaa cccgaacuuc      780

aagcuaggca cggccguaca agacgaaguc aucaccuccu ugggaaaacu cauaggcaac      840

gccuccgcga acgccgaagu cgucaacaac uguguacccg uccuaaaaca guuuagagag      900

aaccuaaacc aguacgcucc ggacuacguc aaagggacag cagugaauga acugauuaag      960

ggaauagagu ucgacuucuc aggcgcugcc uacgaaaagg acgugaaaac caugcccugg     1020

uacggcaaga ucgacccauu caucaacgaa uuaaaagcac ucggccuaua uggcaacaua     1080

accuccgcca ccgaaugggc aucggacguc ggaauauacu accucaguaa auuuggacug     1140

uauagcacca acagaaacga caucguccaa agccucgaga aagcagucga cauguacaaa     1200

uacggcaaaa uagccuucgu ggcaauggaa aggaucacau gggacuacga cggcaucggg     1260

uccaacggaa agaaaguaga ccacgacaaa uuucuugacg acgccgagaa acacuaccua     1320

ccaaaaacuu acaccuucga caacggcacc uucauaauca gagcaggaga caaagucagc     1380

gaagagaaaa ucaaacggcu uuacugggcc ucacgugaag ugaaaagcca guuccaccgc     1440

gucgugggaa augacaaggc auuggaagua gggaacgcgg acgacguccu aacaaugaaa     1500

auauucaaca gcccagaaga auacaaauuc aacacuaaca uaaauggagu cuccaccgac     1560

aacggcggcc ucuacauaga accaaggggc accuuuuaca cauacgaacg cacaccucag     1620

caaagcauau uuucacuaga agaacucuuc cgucacgaau acacccacua ccuccaggcu     1680

agauaccucg uugacggacu guggggccag ggccccuuuu augagaaaaa ccgccucacg     1740

ugguucgacg aaggcacagc cgaguucuuc gccggcagca cacgaaccag cggcguacua     1800

ccacgaaaau cgauccucgg cuaccuggca aaagacaaag ucgaucauag guacagccuc     1860

aaaaagacac uaaacagcgg auaugacgac ucugacugga uguuuuacaa cuacggguuc     1920

gccgucgcac acuaccucua cgaaaaggac augcccacau ucaucaaaau gaacaaggcg     1980

auccuaaaca cugacguaaa aagcuacgac gaaauaauaa agaagcuaag cgacgaugcc     2040

aacaagaaca cagaguacca aaaccacauu caggaacuug ccgacaaaua ccagggagcc     2100

ggaaucccgc ucguauccga cgacuaccua aaagaccacg gauacaaaaa ggcauccgaa     2160

gucuacagcg aaauaagcaa ggccgcguca cuaacaaaca cgucagucac cgcagagaaa     2220

ucccaauacu ucaacaccuu uacacugaga gggacauaca ccggcgaaac cucaaaagga     2280

gaguucaaag acugggacga aauguccaag aaacuagacg gaacacucga aucgcuagcu     2340

aaaaacuccu ggagcggaua caaaacccuc acggcuuauu ucaccaacua ccgcgucacg     2400

agcgacaaca agguacaaua ugacguuguc uuccacggcg uccucacgga caacgccgac     2460

aucucaaaca auaaggcccc cauagcaaaa guaacaggac cauccaccgg cgcagucggc     2520

cgaaacauag aguucucagg caaagauucc aaagacgaag acgggaaaau cguuaguuac     2580

gauugggacu ucggcgacgg cgccaccucg cgagguaaga acuccgugca cgcauacaaa     2640

aaggccggaa ccuacaacgu uacccuaaag gugacagacg acaaaggagc gacggcgaca     2700

gaaucuuuca caaucgaaau caaaaacgaa gacacuacaa cacccaucac gaaagaaaug     2760

gagcccaacg acgacaucaa ggaagcaaac gggccgaucg uugaaggagu aaccgucaaa     2820

ggagaccuca acgggagcga cgacgcagac accuucuacu ucgaugucaa agaggacggg     2880

gacguaacaa ucgagcuccc cuacucagga agcagcaacu ucacauggcu aguguacaag     2940

gagggcgacg accagaacca cauagcgucc ggcaucgaca aaaacaacuc aaaaguaggc     3000

accuucaaaa guaccaaagg ccgccacuac guuuucaucu acaagcacga cuccgccucc     3060

aacauaagcu acucgcuaaa caucaagggc uuaggcaacg aaaaacugaa agaaaaagaa     3120

aacaacgacu caucugacaa ggccaccgua auacccaauu ucaacacaac caugcagggc     3180

ucacugcucg gagacgacuc acgagauuac uacuccuuug aaguaaaaga agaaggcgaa     3240

guaaacaucg aauuggauaa gaaagacgag uucggcguga cguggacacu ucacccagaa     3300

ucaaacauca acgacaggau aaccuauggg caaguagacg gcaacaaagu aucuaacaag     3360

gucaagcucc gccccggcaa guacuaccug cucgucuaca aauacagcgg aucuggaaac     3420

uaugaacucc gcguaaacaa auaaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  2224
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt9)

<400>  2224
gggagaaagc uuaccaugaa cuuccucaaa aucauacuga accgcggaaa aaccaugaag       60

agaaagugcc uauccaaaag guuaaugcuc gccauaacca uggccacgau auucacagug      120

aacucgaccc ucccgauuua cgccgccgua gacaaaaaca acgcgaccgc cgcgguacag      180

aacgagucca aacgguacac gguauccuau cucaagaccc ucaacuacua cgacuugguc      240

gaccuucucg ucaaaacaga gauagaaaac cuucccgauc uauuccaaua cucuagcgac      300

gccaaagagu ucuacggaaa caaaacaaga augucguuca ucauggacga gaucggccgc      360

cgcgcuccuc aauacacaga aauagaccac aaaggcauac ccacccuggu cgaggucguc      420

cgcgccggcu ucuaccuagg uuuccacaac aaagaacuaa acgaaaucaa caagcgcagc      480

uucaaagaaa gggucauacc cuccauacug gcuauccaga aaaaccccaa cuucaaauug      540

ggaaccgaag uacaagacaa aauagucuca gccacaggcc ugcucgcagg uaacgagacu      600

gcaccaccgg aagugguaaa uaacuucacc ccgauacucc aagacuguau caagaacauc      660

gaccguuacg cccucgacga ucucaaaagc aaagcacucu ucaacgugcu cgcagcacca      720

acguaugaua ucacugaaua ccugagagca accaaagaaa aaccggagaa cacccccugg      780

uacgggaaaa ucgacggguu cauaaacgaa uugaagaaac uggcccuuua cggcaaaaua      840

aacgacaaua acucauggau aaucgacaac ggaaucuacc acauagcacc ccucggcaaa      900

cuccacagua acaacaaaau agggaucgag acccuaaccg aagugaugaa gguuuacccc      960

uaucucucaa ugcagcaucu ccagagugca gaccaaauaa aaaggcauua cgacucaaaa     1020

gacgccgagg gcaacaagau accucucgac aaguucaaga aagagggcaa agaaaaguac     1080

ugccccaaaa ccuacacguu ugacgauggu aaagucauca uaaaggcagg agcacgaguc     1140

gaagaagaaa aagucaaacg ucuuuacugg gccagcaagg aaguaaacag ccaguucuuc     1200

cgagucuacg gcaucgacaa accacucgag gaaggcaacc cggaugacau ccucacaaug     1260

gugaucuaca acagcccgga ggaguacaaa cuuaacuccg ucuuguacgg cuaugacacc     1320

aacaauggcg ggauguacau cgaaccagaa ggaacuuucu ucaccuauga gcgcgaagcc     1380

caagagucca ccuauacccu cgaggaacuc uuccgacacg aauacacuca uuacuuacaa     1440

ggccgcuacg caguacccgg gcaauggggc cgcaccaagc uauacgacaa ugacagacua     1500

acuugguacg aggaaggcgg agccgaacua uucgcaggcu ccacacgcac cucaggaaua     1560

cucccucgca aaagcauagu auccaacaua cacaacacca cccgaaacaa cagauauaaa     1620

cuaagcgaca ccguccacag caaauacgga gcgagcuucg aguucuacaa cuacgccugc     1680

auguuuaugg acuauaugua caacaaagau augggcauac ucaacaaacu uaacgaccua     1740

gcaaagaaca acgacgucga cggcuacgac aacuacauac gggaccucag cucgaacuau     1800

gcacuaaacg acaaauacca agaccacaug caggaacgca uagacaacua cgaaaaccuc     1860

accguacccu ucgucgcaga cgacuaccua guccgacacg cguacaaaaa ucccaacgaa     1920

aucuacuccg aaaucagcga agucgccaag cugaaggaug ccaaaagcga agugaagaaa     1980

ucacaauauu ucucaaccuu cacgcuccgc ggcucauaca cagguggcgc cuccaaagga     2040

aaacuagagg aucaaaaagc aaugaacaag uucauagacg acucccucaa aaagcucgac     2100

acauacuccu gguccggcua caaaacacuu accgcguacu ucaccaacua caaaguagac     2160

uccucgaauc gaguaaccua cgacgucgua uuccacggcu accuuccaaa cgaaggcgac     2220

uccaaaaacu cccuacccua cggaaagaua aacggcaccu acaaagguac cgaaaaggag     2280

aaaaucaaau ucuccagcga agggucauuu gacccagacg gaaaaaucgu cuccuacgaa     2340

ugggacuucg gagacggaaa uaagucaaac gaagaaaacc ccgaacacag cuacgacaaa     2400

gugggaaccu acaccguaaa gcucaaagug acagaugaca aaggcgaauc aaguguaagu     2460

acgaccacug cugagauaaa agacuugucg gagaauaaac uucccguaau cuacaugcac     2520

guccccaaau caggagcacu aaaccagaaa gucguauucu acggcaaagg aaccuacgac     2580

cccgacggcu caauagccgg auaucaaugg gauuucgggg acggaagcga cuuuucgucg     2640

gaacagaacc ccagccacgu guacacgaag aaaggggaau acaccgucac ccugcgggua     2700

auggacagcu caggccaaau guccgagaaa acaaugaaaa uaaaaaucac cgaccccguc     2760

uaccccaucg gcacggaaaa agaacccaac aacuccaaag aaaccgcauc cggcccaauc     2820

gugcccggca uacccgucuc cggcacaaua gaaaauaccu ccgaccaaga cuacuucuau     2880

uucgauguca ucacccccgg agaggucaaa aucgacauca acaaacuggg cuacggcgga     2940

gcaaccuggg uagucuacga cgagaacaac aacgccguca guuacgcaac cgacgacggg     3000

caaaaccuca gcggaaaguu caaagccgac aaaccaggaa gauacuacau ccaccuauac     3060

auguucaaug gcagcuacau gcccuacaga auuaauaucg agggauccgu gggccgcuaa     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  2225
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt9)

<400>  2225
gggagaaagc uuaccaugaa acgaaaaugc cuuagcaaac gccugaugcu cgccauuacc       60

auggcgacaa uauucaccgu gaacaguacg cucccuaucu acgcagccgu agacaaaaac      120

aacgcaaccg cagccguaca gaacgagucc aaacgcuaca ccgucuccua ucucaagacc      180

cuaaacuacu acgaccuugu agaccuccuc gugaagaccg aaaucgaaaa ccuacccgac      240

cucuuccaau acuccagcga cgccaaggag uucuacggaa acaaaacccg aaugagcuuc      300

auaauggacg aaaucggucg ccgcgcgccc caauacacgg aaaucgacca uaaaggaauc      360

ccuaccuuag ucgaggucgu aagagcgggu uucuaccuag gauuccacaa caaagagcua      420

aacgagauca acaaacgcuc cuucaaagaa cgcgugaucc ccucuauccu agccauccag      480

aaaaacccaa auuucaaacu cggcaccgaa guacaagaua aaauaguaag cgccaccgga      540

cuccucgcug gcaacgaaac cgcaccccca gaaguaguga auaacuucac acccauccuc      600

caagauugca ucaaaaauau agaccgauac gcccuggacg auuuaaaaag caaagcacuc      660

uucaacguac ucgcugcacc cacauacgac aucacagagu acuugagggc aacgaaagag      720

aaacccgaaa acacccccug guacggaaaa auagacggcu ucaucaacga acuaaagaaa      780

uuggcgcuau augggaaaau caacgacaac aacaguugga uaaucgacaa cggcaucuau      840

cacauagcac cccucggcaa acuccauagc aacaacaaaa uaggcauaga aacacuaacu      900

gaagucauga aaguauaccc cuaucucagc augcaacacc uacaauccgc cgaccaaauc      960

aaacgccacu acgacagcaa agacgcagaa ggcaacaaaa uaccccucga caaguucaag     1020

aaagaaggaa aagagaaaua cugccccaaa accuacaccu ucgacgacgg caaaguaauc     1080

aucaaggccg gagcacgagu agaagaagag aaaguaaaac gacucuacug ggcgagcaaa     1140

gaagucaaua gccaauucuu ccgcguuuac gguaucgaua aaccgcuuga agaaggcaac     1200

ccagaugaca uccuaacgau gguuaucuau aacagucccg aagaauacaa acucaacagc     1260

guccuuuaug gguacgacac caauaacggc gggauguaca ucgaacccga ggggaccuuc     1320

uucacauacg aacgagaagc ccaagaaucc accuacacac uagaagaacu cuuccgccac     1380

gaauacaccc acuaucuuca gggcagauac gccguaccag gacaaugggg gaggaccaaa     1440

uuauacgaca acgaccgacu cacaugguac gaagaaggcg gcgccgaguu auucgcugga     1500

aguacucgaa ccuccggcau ccuuccccga aaaagcauag ucucgaacau ccacaacaca     1560

acccguaaca aucgcuacaa acuauccgau acaguccaca gcaaauaugg agcuagcuuu     1620

gaguucuaca acuaugccug cauguucaug gacuacaugu acaacaagga caugggcauc     1680

cucaacaaac uaaacgaccu ggcgaaaaac aacgacguag acggcuacga caacuacaua     1740

cgcgaucuua gcucuaacua cgcccuaaac gacaaauauc aagaccauau gcaggaacgg     1800

aucgauaauu acgaaaaucu cacaguaccc uucgucgccg acgacuaccu aguccggcau     1860

gcauacaaaa acccgaauga gauauacucc gagaucucag aagucgcaaa acugaaagac     1920

gcaaagucgg aaguuaaaaa gagccaauac uucagcacau ucacccuccg cggaucuuac     1980

accggcgggg ccuccaaggg gaaacuugag gaccaaaaag caaugaacaa auuuaucgac     2040

gacagccuca aaaagcucga caccuacagc uggagcgggu acaaaacacu uacggcauac     2100

uucaccaauu acaaagucga cucgagcaau cgggucaccu acgacguggu cuuccacggc     2160

uaccuaccga acgaaggcga cagcaaaaac ucacuaccgu acggcaaaau aaacggcacg     2220

uauaaaggga ccgaaaaaga aaagaucaag uucucaucag aaggcuccuu cgacccagac     2280

ggaaaaauag ugagcuauga gugggauuuc ggcgacggga acaaaucaaa cgaagagaac     2340

ccggagcaca gcuacgacaa agucgggacc uacaccguca aacuaaaagu caccgaugac     2400

aaaggcgagu ccucaguauc cacgaccacg gcugaaauca aagaccugag cgaaaacaag     2460

cucccaguca uauacaugca cgucccgaaa uccggcgccc uaaaccagaa agucgucuuc     2520

uacggcaaag gcacuuacga cccagacggc agcauagcag gauaccaaug ggacuucggg     2580

gacggcuccg acuucucauc agaacagaac ccaucacacg ucuacaccaa aaagggcgag     2640

uacacaguua cacuccgcgu gauggacucc uccggacaaa ugagcgagaa aacaaugaaa     2700

auaaaaauaa ccgacccggu auacccaaua ggcacggaaa aggaaccuaa caacagcaaa     2760

gaaacagcau caggucccau uguacccggc aucccagucu caggaaccau cgaaaacacc     2820

uccgaccaag acuacuucua cuucgaugua auaacacccg gcgaaguaaa aaucgacauc     2880

aacaaacucg gguacggggg agcaaccugg gucguauacg augaaaacaa caacgcuguc     2940

ucauacgcaa ccgacgacgg acagaaccug agcggcaagu ucaaagccga caaaccaggg     3000

agguacuaca uacaccucua cauguucaau gguagcuaca ugccuuaccg uauaaauauc     3060

gaaggaucug uaggacgaua aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  2226
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt9)

<400>  2226
gggagaaagc uuaccaugaa augggugacc uucauaagcc uucucuuccu cuucucaucc       60

gccuacagcg uacaaaacga gucgaaaaga uacaccguau cauaccucaa gacccucaac      120

uacuacgauc ucgucgaucu auuagucaag acagaaaucg aaaaucuacc cgaccuauuc      180

caguacucau cggacgccaa agaguucuac ggcaacaaaa cacgaaugag cuucauuaug      240

gacgaaauag guagacgagc gccgcaguac acggaaaucg accacaaagg gauccccacc      300

uuagucgaag uuguacgcgc gggcuucuac cuaggauuuc acaacaaaga acuuaacgaa      360

aucaacaaac gcaguuucaa agaacgcguc auccccagca uccuagcgau ccagaaaaac      420

cccaauuuua aacucggcac cgaaguacag gacaagauag ugucagcaac aggccugcuc      480

gccggaaacg aaacggcccc acccgaagua gucaauaacu ucacacccau acugcaggac      540

ugcaucaaaa auaucgaccg auacgcacuc gacgaccuca agagcaaagc ccucuucaac      600

gugcucgccg ccccaaccua cgacauaacc gaauacuuga gggccacaaa agaaaaaccc      660

gaaaacaccc caugguacgg caaaauugac ggauucauca acgagcugaa gaaacucgcc      720

cucuacggga aaaucaauga caacaacagc uggaucaucg acaacggcau cuaccacauu      780

gccccgcuag gcaaacuaca cuccaacaac aaaaucggca ucgaaacgcu cacggaaguc      840

augaaaguau auccauaucu auccaugcaa caccuccaau cugccgacca aaucaaacgc      900

cacuacgaca gcaaggacgc ggaaggaaac aaaaucccac ucgacaaguu uaagaaggaa      960

ggcaaagaaa aauacugccc uaaaaccuac acguucgaug acgggaaagu aauuaucaaa     1020

gccggcgccc gagucgaaga ggaaaaggug aaacgccuau acugggccuc caaagagguu     1080

aauucacaau uuuuccgagu cuauggcauc gacaaaccac ucgaggaagg uaaccccgac     1140

gauauccuca ccaugguaau auauaauucg cccgaggaau auaaacucaa cagcgucuua     1200

uacggcuacg acaccaacaa cgguggcaug uacaucgagc cggaaggcac cuucuucacc     1260

uacgagcgug aagcccaaga auccacguac acacuugagg aacuauuccg acaugaauac     1320

acccacuacc ugcaaggccg guacgcagua ccuggccagu ggggccgcac uaaacucuac     1380

gacaacgacc gucucaccug guacgaagaa gguggagccg aacucuucgc cggcuccacc     1440

cgcaccagcg gcauccuacc ccgaaaaucc auagucucga acauucacaa cacaacccga     1500

aauaaccgcu acaaacucag cgacaccgua cacucaaaau acggagccag cuucgaguuc     1560

uacaacuacg cgugcauguu cauggacuac auguacaaca aagauauggg gauucuaaac     1620

aaacuuaacg accucgccaa aaauaacgac gucgacgguu acgacaacua uauacgagau     1680

cuuucaucga acuacgcacu aaacgacaaa uaccaggacc acaugcaaga acgcaucgac     1740

aacuacgaaa accucaccgu ccccuucguc gcagacgauu accucguccg acacgcauac     1800

aagaacccca acgaaauaua cucggagauc agcgaagucg ccaagcucaa agaugcaaaa     1860

uccgaaguca aaaagucaca guacuuuagc acauucacac uccgcgggag cuacaccggc     1920

ggcgcgucca agggaaagcu cgaagaccaa aaagccauga acaaauuuau agacgacucc     1980

cucaagaaac ucgacaccua cucguggagc ggcuacaaaa cacuuaccgc auacuucacc     2040

aacuacaaag uagacagcuc aaaucgggua acuuacgacg uagucuucca cggcuaccuu     2100

cccaaugaag gagacagcaa gaacucacuc ccuuacggca aaauaaaugg aacguacaag     2160

ggcacggaaa aggagaaaau caaauucagc uccgaaggcu ccuucgaccc cgacggaaaa     2220

auaguaucau acgaauggga cuucggcgac ggcaacaaga guaacgaaga aaaucccgaa     2280

cacucauacg acaaagucgg cacguacacc gucaaacuaa aaguaacaga cgacaaaggc     2340

gaauccucag ugaguacgac caccgcagaa aucaaagacu uaucagaaaa caaacucccc     2400

guaauauaca ugcacguccc aaagagcggg gcacucaacc aaaaagucgu cuucuacggc     2460

aaaggaaccu acgacccuga cggauccauc gccggcuacc agugggauuu cggcgacgga     2520

agcgacuucu caucggagca aaacccaagc cacgucuaca cgaaaaaggg agaauacaca     2580

gugacacucc gaguaaugga cuccucaggg cagauguccg agaaaaccau gaaaauaaag     2640

aucaccgacc cugucuaccc caucggaacc gaaaaggagc cuaacaauuc caaagaaacc     2700

gccagcggac caauaguacc cgguaucccc gucuccggaa ccaucgaaaa cacgucagac     2760

caggacuacu ucuacuucga cgucauaacc ccgggcgaag uaaaaaucga caucaacaaa     2820

cuaggcuacg gcggagccac augggucgua uacgacgaaa acaacaacgc gguaucuuac     2880

gcaacagacg acggccaaaa ccuaagcggc aaguucaaag cagacaaacc cgggcgcuac     2940

uacauccacc uguacauguu caacggaagc uacaugccau acagaauaaa uaucgaaggc     3000

uccguaggac guuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2227
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt9)

<400>  2227
gggagaaagc uuaccaugaa augggucacc uucaucucuc uacuguuccu cuucucuagc       60

gcauauagca ugaaacggaa augucuaucc aaacgccuga ugcuggccau uacgauggcc      120

accaucuuca ccgucaacuc uacccugccg aucuacgccg ccguagacaa gaacaacgcc      180

accgccgcuc gccgccgaag aaagaggguc caaaacgaaa gcaaaagaua cacaguaagc      240

uaccuuaaga cacucaacua cuacgaccuc guagaccuac ucgucaagac agaaauugag      300

aaccuccccg accuauucca auacagcagc gacgccaaag aguucuacgg caacaaaacc      360

cgaaugucuu ucauaaugga ugaaauagga cgcagagcgc cccaauacac ggaaaucgau      420

cacaaaggca uacccacccu aguggaaguc guacgagcug gcuucuaucu ggguuuccac      480

aacaaagaac ugaacgaaau aaacaagcgc agcuucaaag aacgcgugau ccccucaaua      540

cuggcuaucc agaaaaaucc caauuucaaa cuagggaccg aaguccaaga caagaucgug      600

uccgcgacag gacuccucgc cggcaacgaa accgccccgc cggaagucgu uaacaacuuc      660

acgccaauac uacaagacug cauuaaaaac aucgaccgau acgcccuaga cgaucugaaa      720

uccaaggcac uauucaacgu ucuggccgca ccaacauacg acaucacaga guaccugcgu      780

gccacaaaag aaaaaccaga aaauaccccc ugguacggca aaaucgacgg auucauuaau      840

gaguugaaaa agcuagcacu cuacggaaaa aucaacgaca auaacagcug gaucaucgac      900

aacggcauuu accacauagc gccccucggc aaacugcacu ccaacaacaa aaucgguaua      960

gagacacuca cagaggugau gaaaguuuac ccauaccuaa gcaugcaaca ccuucaaucc     1020

gccgaccaaa ucaaacgcca cuacgacucc aaagacgcgg aaggcaacaa aauaccccuc     1080

gacaaauuua aaaaggaggg caaagaaaaa uacugcccaa agaccuacac cuucgaugac     1140

ggcaaaguaa uaaucaaagc aggagccaga gucgaggagg agaaggucaa aaggcuauac     1200

ugggcaucua aggaagugaa cagccaauuc uuucggguau acggaaucga caagccccua     1260

gaagaaggua accccgacga cauccuuaca augguaauau acaacagccc ggaagaguac     1320

aaacucaaca guguucuaua cggauacgau acgaacaacg gaggcaugua caucgaaccg     1380

gagggcaccu ucuucaccua cgagcgagag gcccaagaaa gcacauacac cuuagaagaa     1440

cuguuccgac acgaauacac ccauuaccuc caaggcagau acgcuguccc cggccaaugg     1500

ggacgcacua aacuauacga uaacgaccgc cuaacauggu acgaagaggg uggcgccgaa     1560

cucuucgccg gcucaacgag aacgagcgga auccugccgc gcaaaagcau cgucagcaac     1620

auacacaaca caacgcgaaa caaucguuac aaacucucgg acacggucca cucaaaauac     1680

ggcgcgucau ucgaguucua caacuacgcc ugcauguuca uggauuacau guacaauaag     1740

gacaugggca uccuaaacaa acucaacgac cucgcuaaaa acaacgacgu cgacggcuac     1800

gacaacuaua uccgagaccu aagcucgaac uacgcacuca augacaaaua ccaagaccac     1860

augcaagagc gcaucgacaa cuacgaaaac cuaacaguac ccuucguugc ggacgacuau     1920

cucgucaggc acgcauacaa gaacccaaac gagauauaca gcgaaaucag cgagguagcc     1980

aaacuuaagg acgccaaauc cgaagucaag aaaucgcagu acuucucaac cuucacgcua     2040

cguggcagcu acaccggggg agcaagcaaa ggaaaacucg aggaccaaaa agcaaugaac     2100

aaguuuauug acgacagccu aaagaaacua gauacauauu ccugguccgg cuacaaaacg     2160

cuaacggcau acuucacgaa cuacaagguu gacucaagua accgcguaac auacgacgua     2220

guuuuccacg gauaccuacc aaaugaaggc gacuccaaaa acucgcugcc auacggaaaa     2280

aucaauggca cauacaaagg gacagagaag gagaaaauca aauucaguuc agaaggaucc     2340

uucgacccag acggcaaaau cguuucauau gaaugggauu ucggagacgg gaacaaauca     2400

aacgaagaaa acccugagca cagcuacgac aaagucggca cauauacagu aaagcucaaa     2460

gucacggacg acaagggcga gagcagcgua agcacgacca ccgcagaaau caaggaccuc     2520

uccgaaaaua aacucccagu cauauacaug cacguaccaa aaucgggcgc ccucaaccag     2580

aaaguagugu ucuacggaaa aggcacauac gauccggacg gauccauagc aggcuaccaa     2640

ugggauuucg gagaugggag cgacuucucg agcgaacaaa acccgucaca cgucuacacu     2700

aaaaagggcg aguacaccgu aacccuucgg guaauggacu ccuccggaca aaugucugag     2760

aaaaccauga aaaucaagau aaccgaccca guauacccca ucggcaccga aaaagaacca     2820

aacaacucca aagaaacugc cuccggcccc aucguaccgg gaaucccagu cuccggcacc     2880

aucgaaaaca ccagcgacca agauuacuuc uacuucgacg uaaucacccc cggagaaguc     2940

aaaaucgaca ucaacaaacu gggcuacgga ggagcuaccu ggguagucua cgacgaaaac     3000

aacaacgccg ucaguuacgc caccgacgac gggcaaaacc uguccgguaa auuuaaggcc     3060

gacaagccag ggcgauacua cauccaccug uauauguuua acggauccua uaugcccuac     3120

cgaauaaaua ucgaaggaag uguaggccgc uaaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  2228
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt9)

<400>  2228
gggagaaagc uuaccauggg aacauggaua cucuucgcau gccuccucgg cgcagccuuc       60

gccaugcccc ucccucccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc      120

cucacacccc ucaaauggua ucaauccauc agaccacccu accccuccua cggcuacgaa      180

cccaugggcg gcuggcucca ccaccaaauc auccccgucc ucucacaaca acacccuccc      240

acccacaccc uccaacccca ccaccacauc cccguagucc ccgcccaaca acccgucauc      300

ccccaacaac ccaugaugcc cguccccggc caacacucaa ugacccccau ccaacaccac      360

caacccaacc ucccaccacc cgcccaacaa cccuaccaac cccaacccgu ccaaccccaa      420

ccccaccaac ccaugcaacc ccaaccaccc guacacccca ugcaaccccu cccaccccaa      480

ccaccccuac cucccauguu ccccaugcaa ccccucccac ccaugcuccc cgaccucacc      540

cucgaagccu ggcccuccac cgacaaaacc aaacgcgaag aaguagacua aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  2229
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt9)

<400>  2229
gggagaaagc uuaccaugcc ccuacccccc cacccaggcc accccggcua cauaaacuuc       60

uccuacgaag uacucacacc ccuaaaaugg uaccaaucca uccgaccccc cuaccccuca      120

uacggcuacg aacccauggg cggcugguaa ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  2230
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt9)

<400>  2230
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua cauaaacuuc       60

ucauacgaag uccucacccc ccuaaaaugg uaccaaucca uccgcccccc ccccaugcuc      120

cccgaccuca cacucgaagc cuggcccuca accgacaaaa caaaacgcga agaagucgac      180

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  2231
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt9)

<400>  2231
gggagaaagc uuaccauggc cguaauggcc ccccgaaccc ucguccuccu acucucagga       60

gcccucgccc ucacccaaac cugggccaug ccccucccac cccacccagg ccaccccgga      120

uacaucaacu ucuccuacga aguacucacc ccccuaaaau gguaccaauc cauccgcccc      180

cccuaccccu cauacggcua cgaacccaug ggcggauggu aaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  2232
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt9)

<400>  2232
gggagaaagc uuaccauggc cguaauggca ccccgcaccc ucguccuacu ccuauccggc       60

gcccucgccc ucacacaaac cugggccaug ccccucccac cccaccccgg ccaccccggc      120

uacauaaacu ucuccuacga aguccucacc ccacucaaau gguaccaauc cauccgccca      180

ccacccaugc uacccgaccu cacacucgaa gccuggcccu ccaccgacaa aacaaaacgc      240

gaagaagucg acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  2233
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt9)

<400>  2233
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccuagucgg cgccgccuuc       60

gccaugcccc ucccacccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc      120

cuaacacccc uaaaauggua ccaauccaug auccgcccac ccuacuccuc cuacggcuac      180

gaacccaugg gcggauggcu ccaccaccaa aucauccccg ucgucuccca acaacacccc      240

cucacccaca cccuccaauc acaccaccac auccccguag uccccgccca acaaccccgc      300

guacgacaac aagcccucau gcccgucccc ggccaacaau ccaugacccc cacccaacac      360

caccaaccca accucccacu ccccgcacaa caacccuucc aaccccaacc cguccaaccc      420

caaccccacc aaccaaugca accccaacca cccguccaac ccaugcaacc ccucuuaccc      480

caaccacccc uaccacccau guucccccuc cgcccccuac cacccauccu ccccgaccuc      540

caccucgaag ccuggcccgc caccgacaaa acaaaacaag aagaagucga cuaaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  2234
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt9)

<400>  2234
gggagaaagc uuaccaugcc ccuaccaccc cacccaggcc accccggcua caucaacuuc       60

ucauacgaag uccucacccc ccuaaaaugg uaccaaucaa ugauccgccc cccauacuca      120

uccuacggcu acgaacccau gggcggcugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  2235
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt9)

<400>  2235
gggagaaagc uuaccaugcc ccuccccccc cacccaggcc accccggcua caucaacuuc       60

uccuacgaag uacucacccc ccuaaaaugg uaccaaucca ugauccgccc cccccccaua      120

cuccccgacc uccaccucga agccuggccc gccacagaca aaaccaaaca agaagaagua      180

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  2236
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt9)

<400>  2236
gggagaaagc uuaccauggc agucauggca ccccgcaccc ucguccuccu ccucuccggc       60

gcccucgccc uaacccaaac cugggcaaug ccacuacccc cacaccccgg ccaccccggc      120

uacaucaacu ucucauacga aguccuaaca ccccucaaau gguaccaauc aaugauccgc      180

ccacccuacu ccuccuacgg cuacgaaccc augggcggcu gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  2237
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt9)

<400>  2237
gggagaaagc uuaccauggc cgucauggca ccccgaacac ucguccuccu ccucuccggc       60

gcccucgccc ucacacaaac augggccaug ccccucccac cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga aguccucaca ccccuaaaau gguaccaauc caugauccgc      180

ccacccccaa uacuccccga ccuacaccuc gaagccuggc ccgccaccga caaaaccaaa      240

caagaagaag ucgacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  2238
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt9)

<400>  2238
gggagaaagc uuaccauggg caccuggaua cucuucgccu gccuccucgg cgccgccuuc       60

uccaugcccc uaccacccca ccccggacac cccggcuaca ucaacuucuc cuacgaaguc      120

cuaacacccc ucaaauggua ccaaaauaug auacgccacc ccuacacauc cuacggcuac      180

gaacccaugg gcggauggcu ccaccaccaa aucauccccg ucgucucaca acaaacccca      240

caaucccacg cccuccaacc ccaccaccac auccccaugg uccccgccca acaacccggc      300

aucccccaac aacccaugau gccccucccc ggccaacacu ccaugacccc cacccaacac      360

caccaaccca accuaccccu acccgcccaa caacccuucc aaccccaacc cguacaaccc      420

caaccccacc aaccccuuca accccaaucu cccaugcacc ccauccaacc ccuccucccc      480

caaccacccc uuccacccau guucucaaug caaucacucc uccccgaccu cccccucgaa      540

gccuggcccg ccaccgacaa aaccaaacga gaagaagucg acuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  2239
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt9)

<400>  2239
gggagaaagc uuaccaugcc ccuaccaccc caccccggcc accccggcua caucaacuuc       60

uccuacgaag uccuaacacc ccuaaaaugg uaccaaaaca ugauccgcca cccauacacc      120

ucauacggcu acgaaccaau gggcggcugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  2240
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt9)

<400>  2240
gggagaaagc uuaccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc       60

uccuacgaag uccuaacacc ccucaaaugg uaccaaaaca ugauccgaca ccccucccua      120

cuccccgacc ucccccuaga agcauggccc gccaccgaca aaaccaaacg cgaagaaguc      180

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  2241
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt9)

<400>  2241
gggagaaagc uuaccauggc cgucauggca ccccgcaccc uaguccuccu ccucucaggc       60

gcccucgcac ucacccaaac augggccaug ccccuacccc cacaccccgg ccacccaggc      120

uacaucaacu ucucauacga aguccucacc ccacuaaaau gguaccaaaa caugauacgc      180

caccccuaca ccucauacgg auacgaaccc augggcggcu gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  2242
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt9)

<400>  2242
gggagaaagc uuaccauggc cgucauggca ccccgcacuc ucguccuccu acucuccggc       60

gcccuagccc ucacccaaac cugggccaug ccccuacccc cacaccccgg ccaccccggc      120

uacaucaacu ucucauacga aguccucacc ccacuaaaau gguaccaaaa caugauccgc      180

caucccucac uccuccccga ccucccccua gaagccuggc ccgccacaga caaaaccaaa      240

cgcgaagaag ucgacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  2243
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt9)

<400>  2243
gggagaaagc uuaccauggg caccuggaua cucuucgccu gccuccucgg cgcagccuuc       60

uccaugcccc ucccacccca ccccggccac cccggcuaca ucaacuucuc uuacauccgc      120

caccccuaca ccuccuacgg cuacgaaccc augggcggcu ggcuacacca ccaaaucauc      180

cccgucguau cccaacaaac cccacaauca cacgcucucc aaccccacca ccacaucccc      240

augguccccg cccaacaacc cggcaucccc caacaaccca ugaugccccu ccccggccaa      300

cacuccauga cccccaccca acaccaccaa cccaaccucc cccucccagc ccaacaaccc      360

uuccaacccc aacccgucca accccaacca caccaaccac uacaaccaca aucccccaug      420

caccccaucc aaccacuccu cccccaacca ccccucccac ccauguucuc aaugcaaucc      480

cuccuacccg accuuccccu ugaagccugg cccgccaccg acaaaaccaa acgagaagaa      540

gucgacuaag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  2244
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt9)

<400>  2244
gggagaaagc uuaccauggg caccuggauc uucuucgcau gccuccuagg cgccucccuc       60

gccaugcccc ucccacccca ccccggacac cccggcuaca ucaacuucuc cuacgaaguc      120

cucaccccac uaaaauggua ccaaaacaug auccgccacc ccuacaccuc cuacggauac      180

gaacccaugg gaggcuggcu ccaccaccaa aucauccccg ucgucucaca acaaacaccc      240

caaucccacg cacuccaacc ccaccaccac auccccaugg uccccgccca acaacccgga      300

aucccccaac aacccaugau gccccucccc ggacaacacu ccaugacccc cacccaacac      360

caccaaccaa accucccccu ccccgcccaa caacccuucc aaccacaacc cguccaaccc      420

caaccccacc aaccacucca accccaaucc cccaugcacc ccauccaacc acuccucccc      480

caaccacccc ucccacccau guucucaaug caaucccucc uucccgaccu cccccucgaa      540

gccuggcccg ccaccgacaa aaccaaacgc gaagaaguag auuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  2245
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt9)

<400>  2245
gggagaaagc uuaccauggg caccuggaua cucuucgccu gccuacucgg cgccgcauuc       60

ucaaugcccc ucccccccca ccccggccac cccggcuaca uaaacuucuc cuacgaaguc      120

cucacccccc ucaaauggua ccaaaacaug auuagacacc caucccuccu ccccgaccuc      180

ccccucgaag cauggcccgc aaccgacaaa accaaacgcg aagaagucga cuaaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  2246
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt9)

<400>  2246
gggagaaagc uuaccauggg cacauggauc cucuucgccu gccuacucgg agccgcuuuu       60

uccaugcccc ucccucccca ccccggccac cccggcuaca uaaacuucuc cuacgaagac      120

cucuaccucg aagccauccg caucgaccgc accgccuucg uccucacacc ccuuaaaugg      180

uaccaaaaca ugauccgcca ccccuacacc uccuacggcu acgaacccau gggcgguugg      240

cuccaccacc aaaucauccc cguagucuca caacaaaccc cacaauccca cgcccuccaa      300

ccccaccacc acauaccaau gguccccgcc caacaaccag gcauccccca acaacccaug      360

augccccucc ccggccaaca cuccaugacc ccaacccaac accaccaacc caaccucccc      420

cuccccgccc aacaacccuu ccaaccccaa cccguccaac cccaacccca ccaaccccuc      480

caaccccaau cccccaugca ccccauccaa ccucuccucc cccaaccccc acucccacca      540

auguucucaa ugcaaucacu ccuccccgac uuaccccuag aagccuggcc cgccaccgac      600

aaaaccaaac gagaagaagu agacuaagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  2247
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt9)

<400>  2247
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccuccucgg cgccgccuuc       60

uccaugcccc ucccacccca ccccggccac cccggcuaca ucaacuucuc auaugaaguc      120

cucacacccc ucaaauggua ccaaaacaug auccgccacc ccacacccca aucccacgcc      180

cuccaaccac accaccacau ccccaugguc cccgcccaac aaccaggcau cccacaacaa      240

cccaugaugc cccuaccagg ccaacacucc augaccccca cccaacacca ccaacccaac      300

cuaccccucc ccgcacaaca acccuuccaa ccacaacccg uccaacccca accccaccaa      360

ccccuacaac cccaaucccc caugcaccca auccaacccc uccuccccca accaccccuc      420

ccacccaugu ucuccaugca aucacuccuc cccgaccucc cccuagaagc cuggcccgca      480

accgacaaaa ccaaacgcga agaagucgac uaaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  2248
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt9)

<400>  2248
gggagaaagc uuaccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc       60

uccuacgaag uacucacccc ucucaaaugg uaccaaaaca ugauccgaca ccccuacacc      120

uccuacggcu acgaacccau gggcggcugg cuccaccacc aaaucauccc cgucgucucc      180

caacaaacac cccaauccca cgcacuacaa ccccaccacc acauccccau gguccccgcc      240

caacaacccg gcauccccca acaacccaug augccacucc ccggccaaca cuccaugacc      300

cccacccaac accaccaacc caaccucccc cuacccgccc aacaacccuu ccaaccccaa      360

cccguccaac cacaaccuca ccaaccacuc caaccccaau cacccaugca ccccauccaa      420

ccacuccuac cccaaccccc acucccaccc auguucucca ugcaaucacu ccuccccgac      480

cucccccuag aagccuggcc cgccaccgac aaaaccaaac gcgaagaagu cgacuaagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  2249
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt9)

<400>  2249
gggagaaagc uuaccaugcc aggagucgcc cggcuacccc uacuccuagg acuccuccua       60

cuaccacgcc cuggacgacc ccuagaccug gccgacuaca cguacgaccu agccgaagaa      120

gacgacuccg aaccccucaa cuacaaagac cccugcaagg ccgccgccuu ccuaggcgac      180

auagcccuag acgaagaaga ccuccgagcc uuccaagucc aacaagcggu cgaccugcgc      240

cgacacacgg ccaggaaauc auccauaaaa gccgcuguac cgggaaacac aucaaccccc      300

ucaugccaau cgacaaacgg acaaccacaa aggggcgcau gcggaagaug gcgcgggcga      360

ucacgcucac gccgcgcagc cacaagccgc ccggagcgag uguggcccga cgggguaaua      420

cccuucguca uagggggaaa cuucacugga ucacaacggg cagucuuuag acaagcaaug      480

agacacuggg aaaagcauac cugcgucaca uuccuagaac ggaccgacga agauucauac      540

aucguauuca ccuaccgccc augcggaugu ugcucauacg uaggccgaag aggcggcggc      600

ccccaagcga uaucgauagg caagaacugc gacaaauucg ggauaguugu acacgaacua      660

ggacacgucg uaggcuucug gcacgaacac accagacccg accgggaccg gcacguaucc      720

auaguccgcg aaaacaucca acccggacaa gaauacaacu uccuaaaaau ggaaccacaa      780

gaagucgaau cgcuaggcga aaccuaugac uucgauucca ucaugcacua ugcucgcaac      840

accuucucac gaggcaucuu ccucgacacc aucgucccca aauacgaagu uaacggaguc      900

aaaccaccca uaggacaacg cacgcgacuc ucaaaaggcg auaucgcuca agcacgcaaa      960

cucuacaagu gucccgccug cggcgaaacg cuccaggacu cgacaggcaa cuucucaucc     1020

cccgaauacc cgaacggaua cagcgcacac augcacugug ucuggcgaau cucaguaaca     1080

ccaggcgaga aaaucauccu uaacuucaca ucccucgacc uguacagauc ccgccucugc     1140

ugguacgauu acgucgaagu cagagacggg uucuggcgaa aagcaccgcu ccgaggccga     1200

uucuguggau ccaaacugcc agaacccaua gucuccacag acucucgacu cuggguugag     1260

uucagaagcu cuaguaacug ggucggcaaa ggcuucuucg ccgucuacga agcaaucugc     1320

ggaggagacg uaaagaaaga uuacggccac auacaguccc ccaacuaccc cgacgacuac     1380

cggcccagua aaguauguau cuggagaauc cagguaagcg aaggcuucca uguugggcuc     1440

accuuucaga gcuucgaaau agaacgccac gacucaugcg cuuaugacua ucucgaagua     1500

cgcgacggcc acuccgaauc aagcacacuc auaggcagau acugcggaua cgaaaaaccc     1560

gaugacauca aauccacguc cagccgccua uggcucaaau ucgucucaga uggaagcaua     1620

aacaaagccg gauuugcugu uaacuucuuc aaggaaguag acgagugcuc ccgacccaac     1680

cgcggcgggu gcgaacaacg cugccucaac acacucgguu ccuacaaaug cagcugcgac     1740

ccaggcuacg aacuagcccc ugauaagcgu cgcugcgaag cagccugcgg uggguuccuc     1800

acaaaacuaa acggauccau aacaagcccu ggcuggccaa aagaauaucc cccuaacaag     1860

aacugcaucu ggcaacuggu ggcgcccaca caauaccgaa uaagccuaca auuugacuuc     1920

uucgagacag aaggaaauga cgugugcaag uacgacuucg uagaaguccg cuccggguua     1980

accgccgacu ccaagcugca ugggaaauuc ugcggauccg aaaaaccaga agugauuacg     2040

agccaauaca acaacaugcg agucgaguuc aagucagaca acacagucuc caagaaaggc     2100

uuuaaagcuc acuucuucuc agacaaagac gagugcucaa aagacaaugg agggugucaa     2160

caagacugcg uuaacacauu cggguccuac gaaugccaau gccgcucugg guucguacuu     2220

cacgauaaca agcacgacug caaagaagcc ggaugcgacc acaaggugac aagcaccucc     2280

ggcaccauaa cgucccccaa cuggccagau aaauaccccu caaagaaaga augcacgugg     2340

gccaucagua gcacucccgg ccacagaguc aaacucacau ucauggaaau ggacaucgaa     2400

agccagccgg agugcgcgua cgaccaccuc gaaguguucg acggacgcga cgcgaaggcu     2460

ccagugcucg gccgauucug cggauccaag aagccagaac cagucuuagc aacuggaagc     2520

cgaauguucc uacgauucua cuccgacaau uccguucaac gaaaaggcuu ccaagccucc     2580

cacgccaccg aaugcggcgg acaaguccga gcggacguaa aaaccaaaga ccucuacagc     2640

cacgcgcaau ucggggacaa caacuaccca gguggcguag acugcgaaug gguaauaguc     2700

gcagaagaag gcuacggagu cgagcuagua uuccagaccu ucgaaguuga agaagaaaca     2760

gacugcggcu acgacuacau ggaacuauuc gacgguuacg acuccaccgc accccggcuc     2820

ggacgguacu gcggcuccgg cccaccagaa gaaguauacu cagcaggaga cagcguccuc     2880

gucaaauucc acuccgauga uaccauaaca aagaaagggu uucaccuacg cuacacgagc     2940

accaaauucc aagacacucu acacagccgc aaauaaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  2250
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt9)

<400>  2250
gggagaaagc uuaccauggu agccggcacc cgaugccuac ucgcccuccu ucucccccaa       60

guccuccuag gcggcgccgc cggccugguc ccagaacuag gccgccgcaa auucgcagcc      120

gcauccuccg gacgcccauc aucacagccc uccgacgaag uccucuccga guucgaacuc      180

agacuacuau cgauguucgg ccuuaaacaa cgccccaccc caucccguga cgccguaguc      240

ccaccauaca ugcucgaccu auaccgccgc cacuccgggc aacccggauc accagcaccc      300

gaccaccgcc ucgaacgcgc cgcaucccgc gccaacacag uccgcuccuu ccaccacgaa      360

gaaucccucg aagaacuccc cgaaacauca ggcaaaacaa cccgccgauu cuucuucaac      420

cucuccucca uacccacaga agaguucauc accuccgcag aauuacaagu cuuccgcgaa      480

caaaugcaag acgcacucgg caacaacucc uccuuccacc acagaaucaa caucuacgaa      540

aucaucaaac ccgcaaccgc caacagcaaa uucccaguaa cccgacuccu ugacacacga      600

cucgucaacc aaaacgccuc cagaugggaa ucauucgacg ucacaccagc agucaugcgc      660

uggaccgccc aaggccacgc aaaccaugga uucgugguag aagucgccca ccuagaagaa      720

aaacaaggag ucuccaaacg ccacguccgc aucucacgcu cccuccacca agacgaacac      780

ucauggucac aaauccgacc ccuccuagua acauucggac acgacggcaa aggccacccc      840

cuacauaaac gcgaaaaacg acaagccaaa cauaagcaac gaaaacgccu caaaucaagc      900

uguaaacguc auccacucua cgucgacuuc ucugacgucg gcuggaacga cuggaucgua      960

gcaccacccg gcuaccacgc cuuuuacugc cacggagaau gccccuuccc ccucgccgac     1020

caccuaaauu ccaccaacca cgcaauaguc caaacccuag uuaacuccgu caacuccaaa     1080

aucccaaaag caugcugcgu ucccacagaa cucucagcaa ucuccaugcu cuaccuugac     1140

gaaaacgaaa aagucguccu gaaaaacuac caagacaugg ucgucgaagg cugcggcugc     1200

cgauaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  2251
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt9)

<400>  2251
gggagaaagc uuaccaugau acccggcaac cguaugcuca uggucguccu ccucugccaa       60

guacuccucg gcggagccuc acacgcaucu cucauacccg aaacuggcaa aaaaaaaguc      120

gccgaaaucc aaggccacgc aggaggacgc cgcucagguc aaucccacga acuccuacgc      180

gacuucgaag ccacccuacu acaaauguuc ggccuccgac gccgacccca gcccuccaaa      240

uccgccguca uacccgacua caugcgcgac cucuaccgac uucaauccgg cgaagaagaa      300

gaagaacaaa uacacagcac cggccucgaa uaccccgaac guccagccuc ccgcgccaac      360

accguccgcu cuuuccacca cgaagaacac cucgaaaaca uccccggcac auccgaaaac      420

uccgccuucc gauuccucuu caaccuaucc ucaauccccg aaaacgaagu cauauccucc      480

gccgaacucc gucucuuccg cgaacaagua gaccaaggcc ccgauuggga acgcggcuuc      540

caccgcauca auaucuacga agucaugaaa ccaccagccg aagucguacc cggacaccuc      600

aucacacgcu uacuagacac ccgccucguc caccacaacg uaacacgcug ggaaaccuuc      660

gacgucuccc cagcuguucu ccgauggaca cgcgaaaaac aacccaacua cggccucgcc      720

aucgaaguca cccaccucca ccaaacccga acccaccaag gccaacacgu cagaaucucc      780

cgcucucucc cccaaggcuc aggcaacugg gcccaacuac gcccccuacu ugucaccuuc      840

ggccacgacg gacgaggcca cgcacuaacg cgacgccgcc gcgccaaacg cucacccaaa      900

caccacucuc agcgcgccag aaaaaaaaac aaaaauugcc gccgacacuc acuguacguc      960

gacuucagcg acgucggcug gaaugacugg aucgucgccc cccccggcua ccaagcauuc     1020

uacugccacg gcgacugccc auucccacua gcugaccacc ucaacucgac caaccacgca     1080

auuguacaaa cccucgucaa uuccgucaac agcuccaucc caaaagcaug cugcgugccc     1140

accgaacucu ccgcuaucuc caugcucuac cucgacgaau acgacaaagu cguacucaaa     1200

aacuaccaag aaauggucgu cgaaggaugc ggcugccgcu aaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  2252
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt9)

<400>  2252
gggagaaagc uuaccaugcc cggucuaggc cgccgcgcac aguggcucug cugguggugg       60

ggacuacucu gcuccugcug cggcccuccc cccuuacguc cacccuuacc agcagccgcc      120

gccgcggcag caggaggcca acuacucggc gacgguggcu cccccggacg aacggaacaa      180

cccccccccu caccccaauc cucaagcggc uuccucuacc gccgccucaa aacccaagaa      240

aaacgagaaa ugcaaaaaga aauacuaucc guccuaggcc uuccacaccg gccccgccca      300

cuccacggcc ugcaacaacc ccagccaccc gcccuccgcc aacaagaaga acaacaacaa      360

caacaacaac ucccccgggg ugaacccccu ccaggccgcc uaaaaucugc cccucucuuc      420

augcucgacc ucuacaaugc ccuauccgcc gauaacgacg aagauggagc gucagaagga      480

gaacgccaac aaucauggcc ccacgaagcc gccuccucau cccaacgccg acaacccccg      540

cccggcgccg cccacccccu aaaccguaaa ucccugcucg cccccggcuc aggcagcggu      600

ggugcauccc cacucaccuc ggcccaagac uccgcauucc uaaacgacgc agacaugguc      660

augagcuucg ucaaccuagu cgaauacgac aaagaauucu ccccacgcca acgacaccau      720

aaagaauuca aauucaaccu cucacagaua cccgaaggag aagucgucac cgccgcagaa      780

uuccgaaucu acaaagacug cguaaugggu agcuucaaaa accaaacauu ccuaaucucu      840

auauaccaag uacuccaaga acaccaacac cgugacagug accuauuccu ccucgacacc      900

cgagucguuu gggccucaga agaaggcugg cucgaauucg acaucacagc aaccagcaac      960

cuauggguag uaacaccgca acacaacaug ggccuacaac uauccguagu cacccgagac     1020

ggaguacacg uucacccgcg cgcagccggc cucguaggac gcgacggccc cuacgacaaa     1080

cagcccuuca uggucgccuu cuucaaaguc uccgaaguac acguccgcac cacccgcucc     1140

gccuccucuc gacgccgcca acaaucccga aaccgaucca cccaauccca agacgucgcc     1200

cgcguuuccu cugccucaga cuacaauucc ucagaacuca aaaccgccug ccgaaaacac     1260

gaacuauaug uaucauucca agaccuuggc uggcaagacu ggaucaucgc ccccaaaggc     1320

uacgcagcca acuacugcga cggcgaaugc uccuucccac uaaacgccca caugaacgcc     1380

accaaccacg ccaucgucca aacacucgug caccuuauga accccgaaua cguacccaaa     1440

ccaugcugcg cccccaccaa acuaaacgcc aucuccguac ucuacuucga ugacaacucc     1500

aacgucauac uaaaaaaaua ccguaacaug guaguacgcg ccugcgguug ccacugagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  2253
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt9)

<400>  2253
gggagaaagc uuaccaugca cgugcguuca cuacgagcag ccgccccaca cucauucguc       60

gcccucuggg cuccccuuuu ucuccuacgc ucugcccucg ccgacuucuc ccuagacaac      120

gaaguacaca gcucauucau ccaccgccgu cuccgcucuc aagaaagacg cgaaaugcaa      180

cgugaaaucc ucuccauccu cggccucccc caccgacccc gcccccaccu acaaggcaaa      240

cacaacuccg cccccauguu caugcucgac cucuacaacg ccauggccgu agaagaagga      300

ggaggacccg guggccaagg cuucuccuac cccuacaaag ccgucuuuuc cacccaaggu      360

cccccgcucg caucacucca agacucccac uuccucaccg acgccgacau ggucauguca      420

uucgucaacc uugucgaaca cgacaaagag uucuuccacc cccgcuacca ccaucgcgag      480

uuccgcuucg accucagcaa aauucccgaa ggcgaagccg ucaccgccgc cgaguuccga      540

aucuacaaag acuacauccg ugaacgcuuc gacaacgaaa cuuuccgcau cucagucuac      600

caaguccucc aagaacaccu aggccgcgaa ucagaccucu uucuccucga cucacgaacc      660

cucugggccu cagaagaagg auggcucguc uucgacauca cagccacauc caaccacugg      720

gucgucaacc cucgccacaa ccuuggacuc caacuguccg ucgaaacccu cgacggccaa      780

uccauaaacc ccaaacucgc cggccucaua ggccgacacg gaccccaaaa caaacaacca      840

uucauggucg cauuuuucaa agcaaccgaa guccacuuua gauccauccg uuccaccgga      900

ucaaaacaac gcucccaaaa ccgcuccaaa acccccaaaa accaagaagc ccuccgcaug      960

gccaacguag cagaaaacuc cuccagcgac caacgccaag ccugcaaaaa gcacgaacuc     1020

uacguaucau uucgagaccu cggcuggcaa gacuggauaa ucgccccaga aggcuacgcc     1080

gcauacuacu gcgaaggaga augcgccuuc ccccuaaauu ccuacaugaa cgccaccaac     1140

cacgccaucg uccaaacccu cguccacuuc aucaaccccg aaacuguccc aaaacccugc     1200

ugcgccccca cacaacuaaa cgccaucuca guccucuacu uugacgacuc aucuaacgua     1260

auccuaaaga aauaucgcaa caugguaguc cgcgccugcg guugccacua gggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  2254
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt9)

<400>  2254
gggagaaagc uuaccaugaa agccuccgcc gcccuccuau gccuccuccu caccgccgcc       60

gcauucuccc cccaaggccu cgcccaacca gucggcauaa acaccuccac caccugcugc      120

uaccgauuca ucaacaaaaa aaucccaaaa caacgacucg aauccuaccg ccgcaccacc      180

uccucccacu gcccccgaga agccgucauc uucaaaacca aacucgacaa agaaaucugc      240

gccgacccaa cccaaaaaug gguccaagac uucaugaaac accuagacaa aaaaacccaa      300

accccaaaac ucuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  2255
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt9)

<400>  2255
gggagaaagc uuaccaugcu cuuaacccuu aucauacuuc uucccgucgu cagcaaguuc       60

agcuuugucu cacucagugc accccaacac uggagcugcc ccgaaggaac acuugccggc      120

aacggcaaua gcacaugcgu ugggccggcu cccuuccuaa uauucagcca cggaaacagc      180

auauuccgaa ucgacacaga gggaaccaac uacgaacagc ugguagucga cgcuggcgua      240

agcgucauca uggacuucca cuacaacgag aagcgaaucu acuggguaga ucucgaacgc      300

caacuacugc aacggguauu cuugaacggc ucgcgacagg agcgcgucug caauaucgaa      360

aagaacgucu caggaauggc uaucaacugg auuaaugaag aggugauaug gagcaaccaa      420

caggagggaa ucauaaccgu cacagacaug aaggguaaca acucccacau ccuucucagc      480

gcgcucaaau acccugcaaa ugucgccgug gauccugucg aacguuuuau auucugguca      540

agugaaguag ccggcucccu cuacagagcc gaccucgacg guguaggggu caaggcacua      600

cucgaaacgu ccgagaaaau aacagcagua ucgcuggacg uacucgacaa acgccuauuc      660

uggauucagu acaaccgaga aggcagcaac uccuuaaucu gcaguugcga cuacgacgga      720

gguagcgugc auauaaguaa acacccaacg cagcacaacc uauuugccau gucacuguuc      780

ggggaccgca ucuucuacag caccuggaaa augaaaacaa uauggaucgc aaacaaacac      840

accggcaagg auaugguccg caucaaccua cacucuucau ucguaccccu aggggagcuc      900

aaaguagugc acccucucgc ccaaccaaaa gcagaggaug auaccuggga acccgaacaa      960

aagcugugca aacuccgaaa gggcaacugc ucgagcaccg ucugcggaca agaccugcaa     1020

agccaccucu gcaugugugc ggaaggauac gcacucucac gagaccggaa guacugcgag     1080

gacgucaacg aaugcgccuu cuggaaccac ggaugcacuc uuggauguaa gaacacccca     1140

ggauccuauu acuguaccug cccagucgga uucguacuac uaccagacgg aaaacgaugc     1200

caccaacugg uauccugccc ccgaaacgua uccgaaugcu cccacgauug cguccuaacc     1260

ucagaggggc cccucugcuu cugcccagag ggauccgugu uagaacgcga cggcaagacu     1320

ugcagcggcu gcagcagccc agacaacggc gggugcagcc aacuaugcgu accacuauca     1380

ccaguuucau gggaaugcga cugcuucccg gguuacgacc uccagcucga cgaaaaauca     1440

ugugcggcca gcggaccaca gcccuuccuc cuauucgcca auucacaaga cauccggcac     1500

augcacuucg acggcaccga cuacgguacc cuacugagcc aacaaauggg uaugguguac     1560

gcgcucgacc acgacccagu agaaaacaaa auauacuucg cccacacagc ccucaagugg     1620

aucgaacgag ccaacaugga uggaucacaa cgcgagcggc uaauagagga agguguggac     1680

gugccagaag gccuggccgu agacuggaua ggccgcagau ucuauuggac agacagaggu     1740

aaaucacuca ucggacgauc agaccucaac ggcaaaaggu ccaaaaucau cacuaaagag     1800

aacauaucac aaccacgcgg cauagccguc caccccaugg ccaaacgccu cuucuggacc     1860

gacacgggca ucaacccaag aauagagucc agcagccucc agggccuagg aagacuugua     1920

aucgcaucgu ccgaucucau uuggcccagc gggaucacaa ucgauuuccu aacugacaaa     1980

cucuacuggu gcgacgccaa acaaagugua aucgaaaugg caaaccucga cggaucgaaa     2040

cgacggcgcc ucacccaaaa cgauguuggc caucccuucg caguagcagu cuuugaggac     2100

uacgucuggu ucagcgacug ggccaugccc uccguaaugc ggguuaacaa acgcaccggc     2160

aaagaccgag uccgacuaca ggguuccaug cuuaaaccga gcucccuagu uguaguacac     2220

ccacuagcaa aacccggggc cgaccccugc uuauaucaaa acggaggaug cgaacacauc     2280

ugcaagaaac gccucggcac cgcauggugu agcugccgag aaggauuuau gaaagccucc     2340

gacggcaaaa ccugucuggc ccuagauggc caccaacucc uugcgggcgg cgaaguagac     2400

cuuaaaaacc aagugacccc gcuagacaua cucucaaaaa cgcgcgucuc agaagacaac     2460

aucacagaaa gccaacacau gcucguagca gaaaucaugg uaagcgacca agacgacugc     2520

gcacccguag gaugcagcau guaugcacgg ugcauaagcg aaggagaaga cgcgaccugc     2580

caaugccuaa aaggauucgc cggagacggu aagcucugcu cagauauuga cgaaugcgaa     2640

augggaguac ccgugugucc acccgccagc ucaaagugca ucaacacuga aggaggcuac     2700

gucugcagau gcagcgaggg cuaucaaggc gacggcaucc auugccuaga uauagacgag     2760

ugccagcuag gcgagcacuc gugcggcgag aacgcgucgu gcacaaacac ggaagguggc     2820

uauacaugca ugugcgccgg aagacucagc gaaccggguc uaauuugccc cgacagcacc     2880

ccaccuccac accuucgcga agacgaccac cacuacuccg uccgcaacuc ggacucagaa     2940

ugcccccuca gucaugaugg cuacugcuug caugacggcg uuuguaugua uaucgaagcc     3000

cuagacaagu acgcaugcaa cugcgucgua gguuacaucg gagagcgcug ccaauaucgc     3060

gaccuaaaau ggugggaacu cagacacgca ggucacgguc agcaacaaaa gguuaucguc     3120

guagccguuu gugucguggu ccuagucaug cuccuucucc uaucgcucug gggcgcccac     3180

uacuacagaa cccaaaaacu ccuauccaaa aacccgaaaa aucccuacga agaaucgagu     3240

agggacguac guucgcgacg acccgcagac acggaagacg gcaugaguuc gugcccccaa     3300

ccaugguucg uaguuauuaa ggaacaucaa gauuugaaaa acggcggaca gccagucgcc     3360

ggagaggacg gccaagcagc agauggaucc augcaaccca caucauggag acaagaaccc     3420

caacuaugcg gaaugggaac ggaacaaggc ugcuggauuc cagucaguuc cgacaaaggc     3480

ucaugcccac aaguaaugga acgaucguuc cacaugccau ccuacggaac ccaaacacuc     3540

gaaggcggug uagaaaagcc acacagccuc cucucggcaa acccccuaug gcagcagcgc     3600

gcacuagacc cuccccauca aauggagcug acccaauagg gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  2256
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt9)

<400>  2256
gggagaaagc uuaccaugac cgccggcaga cgcauggaaa ugcuaugcgc cggccgaguc       60

cccgcacucc uacucugccu cggcuuccac cuccuacaag ccguccuauc caccacaguc      120

aucccaucau gcaucccagg cgaaagcucu gacaacugca ccgcccuagu ccaaaccgaa      180

gacaaccccc gcgucgccca agucuccauc acaaaaugcu cauccgacau gaacggcuac      240

ugccuacacg gccaaugcau cuaccucguc gacauguccc aaaacuacug cagaugcgaa      300

gucggcuaca ccggaguccg cugcgaacac uucuuccuca caguacacca accucucucc      360

aaagaauacg ucgcccucac cgucauacuc auuauccucu uccucaucac cguagucggc      420

uccacauacu acuucugccg cugguaccgc aaccgcaaau ccaaagaacc caaaaaagaa      480

uacgaacgcg ucaccuccgg cgaccccgaa cucccccaag uauaaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  2257
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt9)

<400>  2257
gggagaaagc uuaccauggc cgaaggcgaa aucacaaccu ucaccgcccu caccgaaaaa       60

uucaaccucc cccccggcaa cuacaaaaaa cccaaacucc uauacugcuc caacggcgga      120

cacuuccucc guauacuccc cgacggcaca gucgacggca cccgagaccg cucugaccaa      180

cacauccaac uccaacucuc agccgaauca gucggcgaag ucuacauaaa auccaccgaa      240

acaggccaau aucucgcaau ggacaccgac ggccuucucu acggcuccca aacccccaac      300

gaagaaugcc ucuuccucga acgccuagaa gaaaaccacu acaacacaua caucuccaaa      360

aaacacgcag aaaaaaacug guucguaggc cucaaaaaaa acggcuccug caaacgcggc      420

ccccgcaccc acuacggcca aaaagccauc cucuuccucc cccuacccgu cucauccgac      480

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  2258
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt9)

<400>  2258
gggagaaagc uuaccauggu agggguagga ggaggggaug uagaagaugu gacgccaagg       60

ccaggagggu gucaaauaag cggaagaggg gcaagaggcu guaacgggau accgggggca      120

gcggcguggg aggcagcgcu gccgagaaga cgaccacgaa ggcauccgag ugugaacccg      180

cggucaagag cggcagggag cccgagaacg agagggagaa gaacagagga aaggccaagu      240

ggaaguagau uaggggauag gggaagaggg agggcgcuac cgggagggag auugggaggg      300

cgagggagag ggagagcgcc agagagggua ggagggcggg ggcgggggag ggggacagcg      360

gcgccgagag cggcaccagc agcgagaggg agcaggccag ggccggcggg gacgauggcg      420

gcgggaagca uaacaacacu gccggcguua ccggaggacg gagggagugg ggcguucccg      480

ccagggcacu uuaaagaucc aaagagguug uauugcaaaa acggaggguu cuuucugagg      540

auacauccag augggagagu agauggagua agggagaaau cggacccaca cauaaaacug      600

caauugcaag cagaagagag agggguagug agcauaaaag gggugugugc aaacagauac      660

cuagcgauga aggaagaugg aagacuguua gcgucgaaau guguaacgga cgagugcuuu      720

uucuuugaaa ggcucgagag caauaacuau aacacauaca ggagcaggaa guauacauca      780

ugguauguag cacucaagag aacgggacaa uacaagcuag ggagcaagac ggggccgggg      840

caaaaggcaa uacuauuucu accgaugucg gcaaagagcu agggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  2259
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt9)

<400>  2259
gggagaaagc uuaccaugca caaauggauc cucaccugga uccuacccac ccuccuguac       60

cgcagcugcu uccacaucau cugccucguc ggaaccauau cccucgccug caacgacaug      120

acccccgaac aaauggccac aaacguaaac ugcagcuccc ccgaacgcca cacccgcucc      180

uacgacuaca uggaaggcgg agacauccgc guacgccgcc uauucugcag aacccaaugg      240

uaccuacgca uagacaaaag aggcaaaguc aaaggcacac aagaaaugaa aaacaacuac      300

aacaucaugg aaauccgcac cgucgcaguc ggaaucguag ccaucaaagg agucgaaagc      360

gaauucuacc uagccaugaa caaagaaggc aaacuauacg ccaaaaaaga augcaacgaa      420

gacugcaacu ucaaagaacu aauccucgaa aaccacuaca acaccuacgc cuccgccaaa      480

uggacccaca acggcggcga aauguucgua gcccucaacc aaaaaggaau acccguccgc      540

ggaaaaaaaa ccaaaaaaga acaaaaaacc gcccacuucc uccccauggc caucaccuaa      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  2260
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt9)

<400>  2260
gggagaaagc uuaccaugaa acuccucccc uccgucgucc ucaaacucuu ccuagccgca       60

guccucuccg cacucgucac cggcgaaucc cucgaacgac uccgacgcgg ccuggccgca      120

ggcaccucca accccgaccc accaaccguc ucaacagacc aacuacuacc ccucggcgga      180

ggccgcgaca gaaaaguccg cgaccuucaa gaagcagacc ucgaccuccu ccgagucacc      240

cucuccagca aaccccaagc ccucgccaca cccaacaaag aagaacacgg aaaacgcaag      300

aaaaaaggca aaggccucgg caaaaaacgc gaccccugcc uacgcaaaua caaagacuuc      360

ugcauccacg gggaaugcaa auacgucaaa gaacuacgcg cccccucaug cauaugccac      420

cccggcuacc acggcgaacg cugccacggc cucucccucc ccguagaaaa ccgacucuac      480

accuacgacc acaccaccau ccucgccguc gucgccgucg uccucuccuc cguaugccua      540

cucgucaucg uaggccuccu aauguuccgc uaccaccgcc gaggcggcua cgacgucgaa      600

aacgaagaaa aagucaaacu cggaaugacc aacucccacu aaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  2261
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt9)

<400>  2261
gggagaaagc uuaccaugug ggucacgaaa cuccucccag cacuacuacu acaacacguc       60

cuauuacacc uccuccuccu acccauagca auacccuacg cggaagggca gcgaaaaaga      120

cgcaacacga uccacgaguu caagaagucc gcaaaaacaa cccuaaucaa aauagacccc      180

gcccucaaaa ucaaaaccaa gaaagucaau accgcagacc aaugcgcaaa ccgcugcaca      240

cgcaacaaag gccucccauu uaccugcaaa gccuucguuu uugacaaagc cagaaagcaa      300

ugccuuuggu ucccauucaa cagcaugagc uccggcguca agaaagaguu cggacacgag      360

uucgaccugu acgaaaacaa agacuacauc cgaaacugca uaaucggcaa aggccgcagc      420

uacaaaggaa cagucuccau aaccaaauca ggcaucaaau gccagccuug gagcuccaug      480

auaccccacg aacacucauu ccucccguca agcuaccgag ggaaagaccu acaagaaaau      540

uacugccgaa acccacgcgg ggaagaaggc ggacccuggu gcuucaccuc aaacccagaa      600

guccgcuacg aaguaugcga caucccccaa ugcucagaag uugaaugcau gaccugcaau      660

ggagaaagcu acagagggcu cauggaccac accgaaagcg gcaaaauaug ccaacgaugg      720

gaccaccaaa caccacaccg acacaaauuc cuccccgaac gauacccgga caaaggguuc      780

gaugacaacu acugccguaa ccccgacggc cagccacgcc cauggugcua cacacuagac      840

ccacacacuc gcugggaaua cugugcaauc aaaacaugcg ccgacaauac caugaacgac      900

acagacgucc cccuggaaac aaccgaaugc auccaaggcc aaggugaagg cuaccgcggc      960

acggucaaua ccauauggaa cggcauaccc ugccaacgau gggacagcca auacccgcac     1020

gaacacgaca ugacaccaga aaacuucaaa ugcaaagacc uucgggaaaa cuacugccga     1080

aaccccgacg gauccgaaag ccccuggugc uucacaaccg accccaacau ccgcguagga     1140

uacuguucac aaaucccaaa cugugacaug agccacggac aggacugcua cagagguaac     1200

ggcaaaaacu acaugggcaa ccucucccaa acacgauccg gacugaccug cagcaugugg     1260

gacaagaaca uggaagaucu ccauagacac aucuucuggg aaccagacgc aagcaaauua     1320

aacgaaaacu acugccgaaa ccccgacgac gacgcccacg gccccuggug cuacacagga     1380

aacccucuga uucccuggga uuauuguccc aucucccgcu gcgagggcga caccaccccc     1440

acaaucguga accuagacca ccccguaaua ucaugcgcaa aaacgaaaca gcuccgaguu     1500

gugaacggca uaccaacuag aacuaacauc ggcuggaugg ucucacuacg auaccguaac     1560

aaacacaucu gcggagguuc gcuaauaaaa gaaagcuggg uccucaccgc acgccaaugc     1620

uuccccagcc gggaucugaa agacuacgaa gccuggcugg gaauacacga cguccacggu     1680

agaggagacg aaaaaugcaa acagguccuc aacguauccc aacucguaua cggcccggag     1740

ggcagugacc ucguacucau gaaacuagcc cgacccgccg uccuugacga cuucguaucc     1800

accauagacc uccccaacua cggcugcacc aucccagaaa agaccagcug cagcgucuac     1860

ggauggggau acaccggccu aauaaauuac gacgggcuac uccgcgucgc ccaccuguac     1920

aucaugggca acgaaaaaug cucccagcac cacagaggca aaguaacccu aaaugaaagc     1980

gaaauaugcg caggggccga gaaaaucggc aguggcccau gcgaaggcga cuacgggggc     2040

ccccuaguau gcgaacaaca uaaaaugcgc augguccucg gagugaucgu ccccggacga     2100

ggcugcgcga ucccaaaucg cccaggcauc uucguccgcg uggcuuacua cgccaaaugg     2160

auacacaaaa uaauacuaac cuacaaagua ccccaaagcu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  2262
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt9)

<400>  2262
gggagaaagc uuaccauggc uaaagcggcg gcaaucggaa uagaccucgg aaccaccuac       60

ucaugcgugg gcguuuuuca gcacggcaaa guagaaauaa uagcaaacga ucaaggaaac      120

aggacaacuc ccucguacgu ggcauuuaca gacacagaga gacugauugg ggacgccgcc      180

aaaaaccaag ucgcacugaa cccccagaac acaguuuucg acgcgaaaag gcucauagga      240

cgaaaauucg gagacccagu gguccaaagu gacaugaagc acuggccauu ccaagugaua      300

aaugacggcg acaaacccaa gguacaaguc ucguacaaag gcgaaaccaa ggcauucuac      360

ccagaagaga uaucguccau gguccucaca aagaugaaag aaauagccga agccuaccuc      420

ggguacccag ucacaaacgc ggucauaacc guacccgcgu acuucaacga cagccaacga      480

caagcgacaa aagacgccgg agucauagca ggccucaacg uacugcgcau aaucaacgaa      540

ccgaccgcgg cagccauagc cuacgggcua gaccgcacag gaaaagggga gcgcaacguc      600

uuaaucuucg accuaggcgg aggcacauuc gacgucucaa uacuaaccau agacgacggc      660

aucuucgaag uaaaagccac agccggggac acgcaccuag gcggcgaaga cuucgauaac      720

cgccuaguaa accacuucgu agaagaguuc aagagaaagc acaagaaaga cauaagccaa      780

aacaaacggg ccgugcgcag gcuaaggacc gcaugcgaac gcgcaaaacg aacccucagc      840

ucaaguaccc aagcaagccu ggaaaucgac agucucuucg aaggaauaga cuucuacacc      900

uccaucaccc gagcgcgauu cgaagaacua ugcagcgacc uauuccgcuc gacacuggaa      960

ccgguggaaa aagcacucag agacgcgaag cuagacaaag cccaaaucca cgaccuagua     1020

uuggugggag gcaguacaag aaucccaaaa guacaaaagc uccuacaaga uuucuucaac     1080

ggaagggacc ucaacaaauc caucaacccc gacgaagcag uggccuacgg ggcagcaguc     1140

caggcagcca uacugauggg agacaaaagc gaaaacgugc aagaccuacu ccuccuggac     1200

guagccccac uaagccuagg acucgaaaca gccggaggag uaaugacagc acugauaaaa     1260

aggaacagca ccauccccac gaaacaaacc caaaucuuca caacguacuc agacaaccaa     1320

cccggagugc uaauacaagu auacgaaggc gagcgcgcaa ugacuaaaga caacaaccuc     1380

cugggcaggu ucgagcuauc aggaauacca ccggcaccac ggggaguccc gcaaauagaa     1440

gugaccuucg acauagacgc caauggcaua cuaaacguaa ccgcaaccga caaaucuacc     1500

gggaaagcaa acaagauaac gaucacgaac gauaaagggc gcuuaagcaa ggaagaaauc     1560

gaacgcaugg uccaagaagc agaaaaauac aaagccgagg acgaaguaca acgcgaaaga     1620

gugagcgcga aaaacgcacu agaaucauac gcguucaaca ugaaaagcgc agucgaagac     1680

gaaggccuca aagggaaaau auccgaggcc gauaaaaaga aaguacuaga caaaugccaa     1740

gaagucauaa gcuggcuaga cgccaacacc uuagccgaaa aagacgaguu cgaacacaaa     1800

aggaaagaac uggaacaagu augcaacccc auuauauccg gccuauacca aggagcugga     1860

ggaccgggac ccggcggauu cggagcccaa ggccccaaag gaggaagugg gagcgggccc     1920

acgauagaag aagucgacua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2263
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt9)

<400>  2263
gggagaaagc uuaccauggc gaaagccgca gccaucggaa uagaccucgg caccaccuac       60

ucaugcgucg gcguauucca acacgggaaa guagagauca ucgcaaacga ccaaggaaac      120

aggaccacac caucauacgu agccuucaca gacaccgagc gccuaaucgg agacgccgcc      180

aagaaccaag uugcgcucaa cccacaaaac acagucuucg acgcaaaacg acugauaggc      240

cgaaaauucg gcgacccagu gguccaaucc gacaugaagc acuggccauu ccaaguaauc      300

aaugacggag acaaacccaa aguacagguc agcuacaaag gagaaacaaa ggccuucuac      360

ccagaagaaa uaagcucaau gguccugacc aaaaugaaag aaauagcaga ggcuuaccuc      420

ggcuaccccg uaacaaacgc ggucaucacc guacccgcau acuucaacga cagccaacgg      480

caagccacga aagacgccgg agucauagca ggccuaaacg uacuccgcau uauaaacgaa      540

ccaaccgccg ccgccaucgc auacggacuc gaccgaacag gcaagggcga gagaaacgua      600

cugaucuucg accucggagg aggaacauuc gacgucagua uacucacgau cgacgacgga      660

auauucgagg uaaaggcaac ggcuggagac acacaccuag gcggagaaga cuucgacaac      720

aggcuuguca accacuucgu cgaagaguuc aaacgaaaac acaagaaaga cauaagccaa      780

aacaaaaggg ccguccguag acuaagaacc gccugcgaaa gagcgaaaag gacacucagc      840

uccucaaccc aagcaagccu agaaauagac ucacuauucg aaggcaucga cuucuacacc      900

ucgaucaccc gugcacguuu cgaagaacua ugcagcgacc ucuuccgcuc aacccuagaa      960

cccguagaaa aagcacuacg agacgcgaaa cuagacaaag cgcaaauaca cgaccugguc     1020

cuaguaggag gcucaacaag aauaccuaaa guacaaaaac ucuugcaaga uuucuucaau     1080

ggccgcgacc ucaacaaaag cauaaaccca gacgaagccg ucgcauaugg agccgcggug     1140

caggcagcaa uccuaauggg agacaaaagc gaaaacgugc aagaccugcu gcuccuagac     1200

guagcaccac ucucacuugg ccucgaaacc gcaggaggcg uaaugacugc acuuaucaaa     1260

aggaacucga ccauacccac caaacagaca caaaucuuca cuacauacuc ggacaaccag     1320

cccggagucc uuauccaagu auacgagggc gaacgcgcga ugacaaaaga caacaaccua     1380

cucggaagau ucgaacucuc aggaauacca ccagccccac gcggcguccc acaaaucgaa     1440

guaacauucg acaucgacgc gaacggaaua uuaaacguca cagccacaga caaaucgacc     1500

ggaaaagcaa acaaaauaac aaucacaaac gacaaaggcc gacuuaguaa agaagaaauc     1560

gagcgaaugg ugcaagaagc ggagaaauac aaagcagaag acgaaguaca aagagagcga     1620

guauccgcca agaacgcccu cgaaucauac gccuucaaca ugaaaagcgc ggucgaagac     1680

gaaggccuaa aggggaagau aagcgaagca gacaagaaga aaguacuaga caaaugccaa     1740

gagguaauca gcuggcuaga cgcaaacacc cucgcugaaa aagacgaguu cgaacacaaa     1800

cgaaaagaac ucgagcaagu cugcaacccc auaaucucgg gccucuauca gggagcggga     1860

ggacccggcc cagggggcuu cggagcgcaa ggacccaaag gcggcagcgg aagcggcccc     1920

acaaucgaag aaguagacua gggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2264
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt9)

<400>  2264
gggagaaagc uuaccauggc cacagccaag gggaucgcaa ucggcaucga ccuaggaacc       60

acauauuccu gcguaggagu cuuccagcac ggcaaagugg aaauaaucgc aaacgaucaa      120

ggcaacagaa caaccccaag cuacguagca uucaccgaca cagagagacu gaucggcgac      180

gccgcgaaaa accaaguggc aaugaaccca cagaacaccg ucuucgacgc caaacggcuc      240

auaggcagaa aauucaacga ccccguagua caagccgaca ugaaacucug gcccuuucaa      300

gucauaaacg aaggcggaaa gcccaaaguc cuaguaagcu acaaaggcga aaacaaggcc      360

uucuaccccg aagaaaucuc gagcaugguc cucaccaagc ugaaggaaac agcagaagcc      420

uuccuaggcc acccaguaac aaacgccgua auaacagugc cagcauacuu caacgacagc      480

caacgacaag cgaccaagga ugcgggugua auagcgggcc ucaacguccu acgaaucaua      540

aacgaaccua cagcggccgc caucgccuac ggacuggaca aaggaggcca gggagaaaga      600

cacguacuga uauucgaccu aggaggcggc accuucgacg ucucaauacu gaccaucgac      660

gauggcaucu ucgaaguaaa agccacugca ggcgacaccc accucggcgg cgaagacuuc      720

gacaaccggc ucgucagcca uuucgucgaa gaauuuaaaa ggaaacacaa gaaagacauc      780

ucccagaaca aaagagcagu cagacgacuu cggaccgcgu gcgaacgcgc aaaacgcacg      840

cuaagcagca guacacaagc aaaccuagaa aucgacuccc uuuacgaagg aaucgacuuc      900

uacacaucaa ucacccgcgc aagguucgag gagcucugcg ccgaccucuu ccguggcacc      960

cuagaacccg ucgaaaaagc acuccgcgac gccaaaaugg acaaggcaaa aauacacgac     1020

aucguacucg ucgggggcuc aaccagaauc cccaaggucc agcgccuacu acaagauuac     1080

uucaacggac gagaccucaa caaaagcaua aauccagacg aagcggucgc guacggcgca     1140

gcaguacagg ccgcgauccu aaugggggac aaaagcgaaa aaguccaaga ccuccuccug     1200

cuagacguag caccgcuuuc ccuaggccua gaaacagccg gagguguaau gaccgcccua     1260

aucaaacgca acagcacaau acccaccaaa caaacccaaa ucuucaccac auacagcgac     1320

aaccagccgg gcguccucau acagguuuac gaaggcgaac gcgcaaugac aaaagacaac     1380

aacuuacuag gacgauucga ccugaccggc aucccaccag cacccagagg cgucccccaa     1440

auagaaguaa ccuuugacau agacgccaac ggcauacuaa acguaacagc cacagacaaa     1500

aguacgggca aagucaacaa aaucaccaua accaacgaca aaggcaggcu cucaaaagaa     1560

gaaaucgaac ggaugguccu agacgcagaa aaauacaaag cagaagacga aguacagcga     1620

gagaaaauag cggccaaaaa cgcacucgaa agcuacgccu ucaacaugaa aagcguugua     1680

uccgacgaag gauuaaaagg aaaaauaagc gaaagcgaca aaaacaaaau acucgacaaa     1740

ugcaacgaac uccuguccug gcuggaagua aaccaacucg ccgaaaaaga cgaguucgac     1800

cacaaacgaa aagaacucga acaaaugugc aaccccauaa ucaccaaacu guaccaaggc     1860

gguugcaccg gaccagccug cggaaccggc uauguacccg gacgcccagc gacaggccca     1920

accaucgaag aggucgacua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2265
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt9)

<400>  2265
gggagaaagc uuaccaugag cgcacgcggc cccgcaaucg ggaucgaucu aggcaccaca       60

uacucgugcg uaggcguauu ccaacacggg aaagucgaaa ucaucgcaaa cgaccaagga      120

aaccgcacca cccccagcua cguagccuuc accgacaccg aacgacucau cggagacgca      180

gccaaaaacc agguagcaau gaacccaacc aacacaaucu ucgacgcaaa aaggcugaua      240

ggccgaaaau uugaggacgc cacgguccaa agugacauga aacauuggcc cuuccgcgua      300

guauccgaag gaggcaaacc caaaguccaa guagaauaca agggcgagac caagaccuuc      360

uucccggaag aaauauccag caugguccug accaaaauga aagaaauagc cgaagccuac      420

cuugggggaa aaguccacag cgccgucaua accguuccag ccuacuucaa cgacagccaa      480

cggcaagcca cgaaagacgc aggcacaaua acaggacuca acguccuucg aauaauaaac      540

gaaccaaccg cagccgcgau cgcauacggg cucgacaaaa aggggugugc agggggcgag      600

aaaaacgugu uaauauuuga ccuaggcggg ggcaccuucg acguaagcau ccucaccaua      660

gaagacggca uauuugaagu caaaagcacc gccggagaca cacaccuggg aggagaagac      720

uucgacaauc ggaugguaag ccaccucgca gaagaguuca agcgcaagca caagaaagac      780

auugggccaa acaaaagggc cgugcgacgc cucagaaccg caugcgaacg cgcaaaacgc      840

acccugagcu caaguacgca agcaagcauc gaaauugaca gucuguacga aggaguagac      900

uucuacacau caauaacacg agcacgcuuc gaagaacuca acgccgaccu cuuccgcgga      960

acacuagaac ccgucgaaaa agcacuccgg gacgcaaaac uggacaaagg ccaaauccaa     1020

gaaauaguac ucgucggggg auccacccga auaccaaaga uacagaaacu acugcaagac     1080

uucuucaacg ggaaagaacu aaacaagucg auaaaccccg acgaagcagu agcguacggc     1140

gccgccguac aagccgcgau ccugauagga gauaaaagug aaaacgugca agaccuacug     1200

cuccuggacg ucacgccccu aucacucggg aucgaaaccg cuggcggagu aaugacaccc     1260

cucauaaaaa ggaacaccac cauaccaacc aaacaaaccc aaacauucac caccuacucg     1320

gacaaccaau caucugugcu aguacaagua uacgaaggcg aacgggcuau gacgaaagac     1380

aacaaucuac uagguaaguu cgaccuaaca ggcauacccc cggcaccccg aggaguacca     1440

caaauagaag uaaccuucga caucgaugca aacgggauac uaaacguaac cgcagccgac     1500

aaaucgaccg gaaaagaaaa caaaaucaca aucacaaacg acaaaggacg ccucagcaaa     1560

gacgacauag accgaauggu ucaggaagca gagagguaca agagcgaaga cgaagcgaac     1620

cgagaccgag uggcggccaa aaacgcacug gaaagcuaca ccuacaauau aaaacaaaca     1680

guugaagacg aaaaacuccg uggaaagauc agcgaacaag acaaaaacaa aauacuagac     1740

aaaugccaag aagucauaaa cuggcuggac cgaaaccaga uggccgaaaa agaugaauac     1800

gaacacaaac aaaaagagcu agagcgcgua ugcaacccca uaaucucgaa acuguaccaa     1860

ggcggaccag gaggaggaag cggaggagga ggaucgggcg caagcggcgg cccgacaauc     1920

gaagaggucg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  2266
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt9)

<400>  2266
gggagaaagc uuaccaugag cguaguaggc aucgaccuag gguuucagag cugcuacguc       60

gcagucgcaa gagcgggugg cauagaaaca auagcaaacg aauacagcga cagaugcacc      120

cccgcaugca ucucguuugg ccccaaaaau agaagcauug gagcugcagc caaaagccaa      180

gucaucagca acgcgaaaaa cacgguacaa ggcuucaagc gguuucacgg aagggcauuc      240

agcgaccccu ucguugaagc ggagaagucc aaccuagcgu acgacaucgu ccaacuaccc      300

accggacuga ccgguauaaa aguaacauac auggaagaag aaaggaacuu uacaacagaa      360

caaguaaccg ccaugcuccu cagcaaacua aaagaaacag cagaauccgu ccucaagaaa      420

cccgucgucg acugcgucgu gucggucccc ugcuucuaca ccgaugcaga aaggcgcuca      480

gucauggacg cgacgcagau agcggggcuc aacugccuac gccuaaugaa cgagacgaca      540

gcagucgccc ucgccuacgg caucuacaaa caagaccuuc ccgcacuaga agaaaaaccc      600

cgaaaugucg ucuucgucga caugggacac ucagcauacc aaguaucugu augcgcguuc      660

aaccgaggca aacuuaaagu gcuggccacc gccuucgaca caacacucgg cggccggaaa      720

uucgacgaag uccuaguaaa ucacuucugc gaagaguucg gcaagaaaua uaaacuagau      780

auaaaaucca aaauacgcgc ccuccugcgc uugagccagg aaugcgaaaa acucaaaaag      840

cuaaugagcg caaacgcguc agaccugcca cugagcauag aaugcuucau gaacgacgua      900

gacguauccg gaaccaugaa ccggggaaaa uucuuagaaa ugugcaacga ccuccuagca      960

cgcguugaac ccccucuaag aucugugcug gaacaaacaa aacugaagaa agaagacauc     1020

uacgcaguag aaaucgucgg aggggcaacu cgaauaccgg ccgucaaaga gaaaaucagc     1080

aaauucuucg ggaaggaacu cagcaccacc cugaacgcag acgaagcggu aaccaggggc     1140

ugcgcgcucc aaugcgccau acugucacca gccuucaaag uacgagaguu cagcauaaca     1200

gacguggucc cauacccaau aagccuccga uggaacucac cagcagaaga aggcucgagc     1260

gacugcgaag uauucagcaa aaaccacgca gcaccauucu ccaaaguccu cacguuuuac     1320

cggaaagaac cguucacccu cgaggcauac uacuccucac cccaagaccu ccccuacccc     1380

gacccagcca ucgcacaauu cagcguccaa aaggucacuc cccagagcga cggcaguagc     1440

agcaaaguca aagucaaagu ccgcgucaac guacacggga ucuucagcgu aucaucagcc     1500

agccucgugg aaguccacaa gagcgaggaa aacgaggaac caauggagac cgaccaaaac     1560

gccaaagaag aagagaaaau gcaagucgac caggaagaac cccacguaga agaacagcag     1620

cagcaaaccc ccgcggaaaa caaagcagaa uccgaagaaa uggaaaccuc gcaagccggc     1680

aguaaagaca agaaaaugga ccaaccaccc caagcaaaga aagcaaaagu aaaaacgucc     1740

acaguagacc ugccaauaga gaaccaacua cuuuggcaaa uagaccgaga aaugcuaaac     1800

uuauacaucg agaacgaagg gaaaaugauc augcaagaua aacuagaaaa agaaagaaac     1860

gaugccaaaa acgcagucga agaguacguu uacgagaugc gggacaaacu aagcggcgag     1920

uacgagaagu ucgucuccga ggacgaccgc aacagcuuca cacugaaacu cgaagacacc     1980

gaaaacuggc uauacgaaga cggcgaagac caaccaaagc aaguauacgu cgacaagcuc     2040

gcggaacuca aaaaccucgg ccaaccaaua aaaauccggu uccaagaaag cgaggagaga     2100

ccaaagcuau ucgaagaacu cggaaaacaa auccagcaau acaugaaaau uauaucaagu     2160

uucaaaaaca aagaagauca auacgaucau cuggacgccg cagacaugac aaaaguagaa     2220

aaaucgacca acgaagcaau ggaauggaug aacaacaaau uaaaucugca aaacaaacaa     2280

agccuaacca uggaccccgu aguaaaauca aaagagaucg aagccaaaau caaagaacuc     2340

accuccacau gcagccccau cauaagcaaa cccaagccca aagucgaacc acccaaagag     2400

gaacagaaaa acgcagaaca aaacggcccc gucgauggac agggcgauaa ccccggaccg     2460

caagccgccg aacaaggcac ggacacagcc gugcccucag acagcgacaa gaaacuacca     2520

gaaauggaca ucgacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  2267
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt9)

<400>  2267
gggagaaagc uuaccauguc agucgucgga auagaccucg gauuccucaa cugcuacaua       60

gccguagcac gcuccggagg uauagagaca aucgccaaug aguacuccga cagguguacc      120

cccgcgugca ucagccuggg cucccgcacu cgcgccaucg gcaacgcggc gaagucccaa      180

aucgucacca acgucagaaa cacaauccac ggauucaaga aacuccacgg acgauccuuc      240

gacgacccca uaguccaaac cgagcgcaua cgccugcccu acgaacuaca gaaaaugcca      300

aauggcagcg ccggcguaaa aguccgcuac cucgaggagg aacgccccuu cgccaucgaa      360

caagucacag gcaugcuauu agcaaagcuc aaagagaccu ccgaaaaugc acucaagaaa      420

cccguggcag acugcguaau cagcauuccg uccuucuuca cagacgcaga gcgacgguca      480

gucauggcag ccgcacaagu cgccggccug aacugucucc gacugaugaa ugagacaacg      540

gccgucgccc ucgcauacgg caucuacaaa caagacuuac cuccgcucga cgaaaaaccg      600

agaaacgucg ucuucaucga caugggacac agcgcauacc aaguccucgu augugcauuc      660

aacaaaggaa aacuaaaagu ucuugccacc acauucgauc cauaccucgg aggccgcaac      720

uucgacgaag cacucguuga cuacuucugu gacgaguuca aaacaaaaua caaaauaaac      780

gucaaagaaa acagccgcgc ccuucuccgu cuauaccagg agugcgaaaa acucaagaaa      840

cucaugagcg ccaacgccag cgaucuccca cuaaacaucg aauguuucau gaacgaccug      900

gacgugaguu ccaaaaugaa ccgugcccaa uucgagcaac ucugcgccag cuuacuagca      960

agaguagaac caccacucaa agcggucaug gagcaagcca aucuccaacg ggaagacauc     1020

agcuccauag agaucgucgg gggagcaacc cgaauacccg cuguaaaaga acaaauaacu     1080

aaauucuucc uaaaagacau aagcacaacc cugaacgccg acgaagcagu cgcccgaggc     1140

ugcgcacucc agugcgccau acucuccccc gcguucaaag uacgcgaguu caguaucaca     1200

gaccucguac cauacucaau cacccuacgc uggaagacau cuuucgaaga cggcuccgga     1260

gaaugcgaag ucuucugcaa aaaucacccc gcccccuuuu ccaaagucau cacauuccac     1320

aaaaaggaac cguucgaacu cgaagcguuu uacacgaacc uccacgaggu accauacccc     1380

gacgcgagaa uaggaucauu caccauacaa aacguauucc cacaauccga cggcgauuca     1440

uccaagguca aagucaaagu aagagucaac auacacggca ucuuuucagu cgccagcgcc     1500

agcgugauug agaaacaaaa ccuugaaggc gaucacagcg acgcccccau ggaaaccgaa     1560

acgagcuuca agaacgaaaa caaggacaac auggacaaga ugcagguaga ccaagaggaa     1620

ggacaccaaa aaugccaugc agaacacaca cccgaggaag aaaucgacca caccggagcc     1680

aaaacgaagu cugccgucag cgauaagcag gaccgucuca accaaacccu caagaaaggc     1740

aaaguaaaaa gcauagaccu accaauccaa agcucacucu gccgccaacu cgggcaagac     1800

cuccuaaacu ccuacauaga aaacgaaggc aaaaugauca ugcaagauaa acuagaaaaa     1860

gaacgcaacg acgccaaaaa cgcagucgaa gaauacgucu augacuuccg agaccggcuc     1920

ggaaccgucu acgaaaaauu cauaaccccc gaggaccuau caaaacuaag cgcuguccua     1980

gaagacaccg agaacuggcu auacgaagac ggagaggacc aaccaaaaca aguauacgua     2040

gacaagcucc aggagcucaa gaaauacggc caacccaucc agaugaaaua cauggagcau     2100

gaagaaagac ccaaagcacu caacgaccuc ggcaagaaaa uccagcucgu uaugaaagua     2160

auagaagccu accgaaacaa agacgagcgc uacgaccacc uagacccaac cgaaauggaa     2220

aaagucgaaa aaugcaucag cgaugccaug agcuggcuca acuccaagau gaacgcgcag     2280

aacaaacuau cccucaccca agaccccgua guaaaaguau cagaaauagu cgcaaaaucg     2340

aaagaacugg acaacuucug caacccaauc aucuacaagc cgaaaccuaa agcagaggug     2400

ccagaagaca aaccaaaagc aaauagcgaa cacaacggac caauggacgg gcaauccgga     2460

acagaaacca aaagcgauag cacaaaagac ucaucccagc acacaaaaag cucaggggaa     2520

auggaggucg acuagggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  2268
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt9)

<400>  2268
gggagaaagc uuaccaugaa acuaagccua guagcggcaa ugcuccugcu cuuaagcgcc       60

gcaagagcag aagaagagga caagaaagag gacgucggca ccgucgucgg cauagaccua      120

ggcaccacgu acagcugcgu cgggguauuc aaaaacggaa gagucgaaau caucgccaac      180

gaccaaggca acagaaucac acccagcuac guagccuuca cccccgaagg agaacgccuc      240

auaggagacg cggccaaaaa ccaacucacc agcaacccag agaacacagu auucgacgca      300

aaacggcuaa ucggccggac cuggaacgac cccagcgucc aacaagacau aaaauuccuc      360

cccuucaagg ucgucgagaa gaaaacaaaa ccauacauuc aagucgacau aggaggaggu      420

caaacgaaaa cauucgcacc cgaggagaua agcgcaaugg uacucaccaa aaugaaagaa      480

accgcagaag cauaccuugg aaagaaaguc acgcaugccg ucgucacagu cccagccuac      540

uucaacgacg cacaaagaca ggcgaccaaa gacgccggca caaucgcagg acugaacgua      600

augcgcauaa ucaacgagcc caccgccgca gccaucgcuu acgggcuaga caaacgagaa      660

ggagagaaaa acauccucgu guucgaccua ggaggaggca cauucgacgu cagccuccua      720

acaaucgaca acggaguguu cgaagucgua gccaccaacg gcgacacgca ccucggagga      780

gaggauuucg accaaagagu aauggaacac uuuaucaaac uauacaaaaa gaaaacaggc      840

aaagacguac gaaaagacaa cagagccgug caaaaacuuc gacgugaggu agaaaaagcc      900

aaacgagcac ugucgagcca acaccaagca agaauagaaa ucgagagcuu cuacgaaggc      960

gaagacuuca gcgaaacccu cacucgagca aaauuugaag aacuaaacau ggaccucuuc     1020

agaagcacaa ugaagccagu acagaaggug cucgaagacu cagaccucaa gaaaagcgau     1080

auagacgaaa ucguccucgu cgggggcagc acccggauac cgaaaaucca acaacucguc     1140

aaagaguucu ucaacggaaa agaaccuagc cguggaauca acccagacga agccgucgcg     1200

uacggagccg cgguccaggc aggcguccua ucaggcgauc aagacacagg cgaccucguc     1260

cuacuagacg ugugcccacu aacacucgga aucgaaaccg ugggcggagu caugaccaaa     1320

cuaauacccc gcaacacagu cguucccacg aagaaaagcc aaauauucag cacggccuca     1380

gacaaccagc ccaccguaac aaucaaaguc uacgaagggg aacgcccacu caccaaagac     1440

aaccaccucc ugggcacguu cgaucugaca ggcauaccac ccgcgccccg cggagucccg     1500

caaaucgaag uaacauucga aauagacgug aacgggauac ugcgcgucac agccgaagac     1560

aaaggaaccg gaaacaaaaa caaaaucaca auaacaaacg accaaaaccg ccuaacacca     1620

gaagaaauag aaagaauggu aaacgacgcc gaaaaauucg cagaagagga caagaaacua     1680

aaagaacgca uagacacccg aaacgaacuc gaaucauaug cauacucccu caaaaaccag     1740

aucggcgaca aagaaaaacu agggggcaaa cugagcuccg aggacaagga aacaauggaa     1800

aaagcaguag aggagaaaau cgaauggcug gaaagccauc aagacgcaga cauagaggac     1860

uucaaagcca agaagaaaga acuugaagag aucguacaac caauaaucuc aaaacucuac     1920

ggcucggcag gaccaccacc gacaggagaa gaagacacgg ccgaaaaaga cgaacuguag     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  2269
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt9)

<400>  2269
gggagaaagc uuaccaugca agccccaaga gaacuagccg uggggaucga ccucgggaca       60

acauacuccu gcguaggcgu guuccaacaa ggaagagucg aaauauuagc aaacgaccaa      120

ggcaacagga ccacaccauc guacguagcg uucacagaca cagaacgccu agugggagac      180

gcagcaaagu cgcaagcagc acuaaaucca cacaacacgg ucuucgacgc aaagaggcua      240

auaggaagga aguucgccga cacaaccguu caaagcgaua ugaagcacug gccauucaga      300

gucgucucgg aaggagggaa accaaaagug cgggucugcu acagaggcga agacaaaaca      360

uucuacccag aagagaucuc cagcauggua cugagcaaaa ugaaggaaac agccgaagcc      420

uaccucggcc aaccagucaa gcacgcgguc auaaccguac ccgccuacuu caaugacagc      480

cagcgccaag ccacaaaaga cgccggggca auagccggac uaaacguacu acgaaucauc      540

aacgaaccca cggcagcagc gauugcauac ggccuagacc gaaggggcgc cggagaacgc      600

aauguccuga uauucgaccu gggagggggc acauuugacg ucuccguacu aucaauagac      660

gcaggaguau ucgaagugaa agcgacggca ggagacacgc accuaggcgg cgaagacuuc      720

gacaaccguc uagugaacca cuucauggaa gaguucaggc gaaaacacgg aaaagaucuc      780

agcggaaaca aacgcgcacu ccgcaggcua agaaccgcau gcgaacgcgc aaaaaggacc      840

cuaagcuccu cgacacaggc cacccucgaa auagacuccc uauucgaagg agucgacuuc      900

uacacaagca ucacccgcgc gcgauucgaa gaacuaugca gcgaccuuuu ccgcucaacc      960

cuagaaccag ucgaaaaagc ucuccgcgac gcaaaauuag acaaagcaca aauccacgau     1020

gucguccuag uaggcggcuc aacgcgcaua ccaaaaguac aaaagcuccu gcaagacuuc     1080

uucaacggga aagaacuaaa caaauccaua aaccccgacg aagcggucgc cuacggcgcg     1140

gcgguacaag cagcgguccu gaugggcgac aagugcgaaa aagugcaaga ccuacuacuc     1200

cucgacgucg ccccauuaag ccucggacug gagacggcag gaggaguaau gacaacacua     1260

auccagcgaa acgcgaccau acccacaaag caaacccaaa ccuuuaccac guacucagac     1320

aaccaaccgg gagucuucau ccaaguauau gagggcgaac gcgcaaugac aaaagacaac     1380

aaccucuugg gccgcuucga acucuccggc aucccacccg cgccccgagg cguaccgcaa     1440

auagaaguga ccuucgacau agacgccaac gggauacuaa gcguaaccgc gacagaccgg     1500

ucaaccggca aagcgaacaa aaucacaauc accaacgaca aaggacggcu aagcaaagaa     1560

gaaguagaac gcauggucca cgaagccgaa caauacaaag ccgaagacga agcccaacgu     1620

gaccgcgucg cagcgaaaaa cucacucgaa gcccacgugu uccacguuaa aggaucccuc     1680

caagaagaaa gccugcgcga caagauaccc gaagaagacc ggagaaaaau gcaggacaaa     1740

ugccgugaag uacucgccug gcucgaacac aaccaacuag ccgaaaaaga agaauacgag     1800

caucaaaaac gagaacugga acaaauuugc agacccauau uuucgagacu guacgggggc     1860

ccaggcgucc caggaggcuc aagcugcgga acccaagcca gacaaggaga ccccagcaca     1920

ggaccaauca uagaggaagu agacuaggga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  2270
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt9)

<400>  2270
gggagaaagc uuaccaugca agcaccccgc gaacucgcag uaggcaucga ccuaggcacc       60

accuacuccu gcguaggcgu cuuccaacaa ggccgcguag aaauacucgc caacgaccaa      120

ggcaaccgca ccacccccuc cuacgucgca uucaccgaca ccgaacgccu cguaggcgac      180

gccgcuaaau cccaagccgc ccuaaacccc cauaacaccg ucuucgacgc caaacgacuc      240

aucggccgaa aauucgcaga caccaccgua caauccgaca ugaaacacug gccuuuccaa      300

gucguaucag aaggaggaaa accaaaaguc cgcgucugcu accgcggaga agacaaaacu      360

uucuaccccg aagaaauauc cagcaugguc cuaucaaaaa ugaaagaaac cgccgaagca      420

uaccucggcc aacccgucaa acacgccguc aucaccgucc caaccuacuu cuccaacucc      480

caaagacaag ccaccaaaga ugcaggcgcc auagccggcc uaaaaguacu ccccaucauc      540

aacgaggcca ccgccgcagc caucgccuau ggacuagauc gccgcggcgc cggcaaacga      600

aacguccuga uauucgaccu cggcggcggc accuucgacg ucucaguacu cagcauagac      660

gcaggcgucu ucgaaguaaa agcaaccgca ggagauacac aucucggcgg cgaagacuuc      720

gacaaucgac uugucaacca cuucauggaa gaguucagac gcaaacacgg caaagaccua      780

ucaggcaaca aacgcgcccu acgccgccua cgaaccgccu gcgaaagagc caaacgaaca      840

cccagcuccu cuacgcaagc aacacucgaa auagacuccc ucuucgaagg cgucgacuuc      900

uacaaaucca ucacccgagc acgauucgaa gaauuaugcu ccgaccuguu ccgcagcacc      960

cucgaacccg uagaaaaagc ccucagagac gcaaagcugg acaaagccca aauccacgac     1020

uucguccucg gaggcggccu ccacucccac ccccaaggcg cagaaguagc ugcaggccuc     1080

cuacaacgac agggagccga acaagaacac caacccuaag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  2271
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt9)

<400>  2271
gggagaaagc uuaccauguc aaaaggaccg gccgucggaa ucgaccucgg caccaccuac       60

agcugcgucg gcguguucca acacggaaaa guggaaauca ucgcaaacga ucaaggcaac      120

aggaccacac ccucguacgu ggcauuuacc gacaccgaac gccucauugg agacgcggcc      180

aaaaaccagg uagcaaugaa ccccaccaac accgucuucg acgcaaaaag gcuaaucggc      240

agacgauucg acgacgcagu cguccagagc gacaugaaac acuggccauu cauggugguc      300

aaugacgcag gccgaccaaa aguccaaguc gaauacaaag gcgaaaccaa gagcuucuac      360

cccgaagaag uauccagcau ggugcugacc aaaaugaaag aaauagcaga ggcauaccua      420

ggaaagaccg ucacgaacgc agucgugaca guacccgcau acuucaacga cucacaacgc      480

caagccacaa aagacgccgg aacaauagcc ggccuaaacg uacuacgcau aauaaacgaa      540

ccaacagcag cagcaaucgc cuacggacuc gacaaaaagg ucggggccga acgcaacguc      600

cuaaucuucg aucuaggagg agggacauuc gaugucagca uccugacaau agaagacggg      660

auauucgaag ucaaaagcac agccggcgac acccaccucg gaggagaaga uuucgacaac      720

cgcaugguca accacuuuau agccgaguuc aagcgcaagc acaagaagga caucagcgaa      780

aacaaacgag ccguacgccg acuacgcacc gccugcgaac gagcaaaacg cacccuguca      840

agcagcacgc aagcgagcau agagaucgac agccucuacg aaggcauaga cuucuacaca      900

uccauaacgc gagcacgguu cgaagaacuc aacgccgacc uguuccgcgg cacccuagac      960

ccaguagaaa aagcccuacg agacgccaaa cucgacaaau cacaaaucca cgacauaguu     1020

cuggucggcg gcuccacaag aaucccuaaa auccaaaaac uacuccaaga cuucuucaac     1080

ggaaaagaac ucaacaaaag cauaaacccc gacgaagcag uggcguacgg agcagccguc     1140

caagccgcga uccuauccgg cgacaagagc gaaaacguuc aagaccuucu ccucuuggac     1200

guaaccccgc uaucauuagg aauagaaacc gcgggaggag uaaugacagu acuaaucaaa     1260

aggaacacua caauaccgac caaacaaaca caaaccuuca cgacauacuc agacaaccaa     1320

ccaggcgugc ucauacaagu cuaugaagga gaacgcgcaa ugacaaaaga caacaaccua     1380

cucggcaagu ucgaacucac agggauccca cccgcacccc gcggaguacc acaaauagaa     1440

guaaccuucg acaucgacgc caacggaauc cucaacguca gcgccgucga caaaucaaca     1500

ggaaaagaga acaaaaucac gauaacaaac gacaaagggc gccugagcaa agaagauauc     1560

gaacgaaugg uucaggaagc cgagaaauac aaagcagagg acgaaaagca acgcgacaaa     1620

gucagcucca aaaacucccu agaaucauac gcguucaaca ugaaagcgac ggucgaagac     1680

gaaaaacuac aaggcaaaau uaacgaugag gauaaacaga aaauacuaga caagugcaac     1740

gaaaucauaa acuggcucga caagaaccaa acagcagaaa aagaagaguu cgaacaucaa     1800

caaaaagaac ucgaaaaagu cugcaauccc auaauaacca aacuguacca aagcgcgggc     1860

gggaugcccg gcgguaugcc gggaggcuuc cccggaggcg gcgccccacc aagcggcggc     1920

gcauccucag gcccaaccau cgaagaaguc gacuaaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  2272
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt9)

<400>  2272
gggagaaagc uuaccaugau aagcgccagc cgcgcagccg cggcgaggcu aguaggcgca       60

gcggcaagua gaggaccgac ggcggcaaga caccaagacu cauggaacgg ccugagccac      120

gaggcguuca gacuggugag ccgacgcgac uacgcaagcg aggccaucaa aggagcaguc      180

gucggaaucg accuagggac gacgaacucg ugcguagcag ugauggaggg aaagcaggcg      240

aagguccugg agaacgcgga aggagcgaga accacgccau cagucguagc auucaccgcg      300

gacggagaga ggcucguggg aaugccagcg aaaaggcagg caguaacaaa cccaaacaac      360

accuucuacg cgacaaaaag gcuaauaggu agaagauacg acgauccaga agugcaaaag      420

gacaucaaaa acguacccuu caagauagua cgagccagca acggagacgc auggguagag      480

gcacauggca agcuauauag cccgagccag auaggggcgu ucguccucau gaagaugaag      540

gaaacggcag agaacuaccu gggacacacg gcaaagaacg cggucauaac agugccagcg      600

uacuucaacg acagccaacg gcaagcgaca aaggacgcag ggcagauaag uggacucaac      660

guccuacgcg ucauaaacga accaacagcg gcugcccucg cauacgggcu cgacaagagc      720

gaagacaaag uaauagcagu auacgaccug ggcggaggca cauucgacau aucuauacua      780

gaaauccaga aagggguauu cgaaguaaag uccacaaacg gcgacacguu ccuuggaggg      840

gaagacuucg accaagcgcu auugcgucac aucguaaagg aguucaagag agagacagga      900

guagaccuca caaaagacaa cauggcgcug caacgaguaa gagaagcagc agaaaaagcg      960

aagugugaac uaagcucuag cguacaaaca gacauuaacc ucccauaucu cacaauggac     1020

aguucagggc cgaaacaccu aaacaugaag cucacaagag cccaguucga gggaauagug     1080

accgaccuaa uccgcaggac aauagcgccg ugccaaaagg cgaugcagga cgcagaagug     1140

agcaagagcg acaucggaga agucauauua guagggggaa ugaccaggau gccgaaagug     1200

caacagacgg ugcaggaccu guucggcaga gcaccgagca aggcaguaaa cccagacgag     1260

gcaguagcga ucggagcggc cauacaaggg ggaguacuug cgggagacgu aacggacgua     1320

cuacuauugg acgugacgcc auuaagccua ggaauagaaa cacuaggugg cguguucacu     1380

aaacucauca aucgaaacac cacgauaccc acaaagaaau cacaaguguu cagcacagcg     1440

gccgacggac agacccaggu cgagauaaaa guaugccaag gagagcgaga aauggccggg     1500

gacaacaaac uacucgggca auucacacug auaggaauac cgccagcacc caggggagua     1560

ccccagauag agguaacauu cgacaucgac gcgaacggaa uaguccacgu cagcgcaaaa     1620

gacaaaggaa cuggcaggga gcaacaaaua gugauccaaa gcagcggcgg acugagcaag     1680

gacgacauag agaacauggu gaaaaacgcg gaaaaauacg cggaggagga caggagaaag     1740

aaagaaaggg uagaagcagu aaauauggcg gaagggauaa uacacgauac cgagaccaag     1800

auggaagagu ucaaggauca acucccagcg gacgaaugca acaaauuaaa agaagaaaua     1860

agcaagauga gggaacuacu agcgcgcaaa gauagcgaaa cgggagaaaa cauaagacaa     1920

gccgcgagca gucuccagca ggccagccua aaacuauucg aaauggcgua caagaaaaug     1980

gcaagcgaaa gagaagggag cgggagcagc ggaacaggag agcaaaaaga agaucagaaa     2040

gaagagaagc aguaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  2273
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt9)

<400>  2273
gggagaaagc uuaccauggc cgacaaagag gcaggcggaa gcgacggacc ccgagaaaca       60

gccccaacau ccgccuacuc cagcccagca agaucacucg gcgacaccgg caucacacca      120

cucucaccgu cucacaucgu caacgacacc gauucaaacg uauccgagca acaauccuuc      180

cuaguagucg ucgccgucga cuucgggaca accuccuccg gcuacgcaua uuccuucaca      240

aaagaacccg aaugcaucca cgucaugcgc cgcugggaag gaggagaccc cggcguaucc      300

aaccagaaaa cgcccacuac cauccuacua acccccgaac gaaaauucca cuccuucggc      360

uacgcugccc gagacuucua ccacgaccuc gacccaaacg aagccaaaca auggcucuac      420

cuagaaaagu ucaaaaugaa acuucauacc acaggcgacc ucaccaugga caccgaucua      480

accgccgcaa acggcaagaa agugaaagcu cuugaaaucu ucgccuacgc ccuucaauac      540

uucaaagaac aagcacuaaa agaacucucc gaccaagcag gcucagaguu cgaaaacucc      600

gacguucgcu gggucaucac aguccccgca auauggaaac aacccgccaa gcaauucaug      660

cgacaagcag cauaccaagc cggucucgca agcccagaaa auucagaaca auuaaucaua      720

gcacucgaac ccgaagccgc guccauauac ugccgcaaac uucgccucca ccaaaugaua      780

gaacucuccu caaaagccgc ugucaacggg uacuccggua gcgacacagu cggcgccggc      840

uucacacaag ccaaggagca cauacgccgc aaccgccaau cgcgaacauu ccucgucgag      900

aacgucaucg gagaaaucug gucagaacuc gaagaaggcg acaaauacgu gguagucgac      960

agcggcggcg gaaccgugga ccuaaccguc caccagauac gccugccaga agggcaccuu     1020

aaagaauugu acaaagccac aggaggaccc uacggaucau uaggagucga cuacgaguuc     1080

gaaaagcugc ucuacaaaau cuucggcgaa gauuucauug aacaauucaa aauaaaacgc     1140

cccgccgcau gggucgaucu gaugauagcc uucgaaucac guaaacgcgc agccgcuccc     1200

gaccgaacca auccacucaa caucacccua cccuucucau ucaucgacua cuauaagaaa     1260

uuccgcgggc acuccgucga acaugcucuc cgaaaaucaa acgucgauuu cgucaaaugg     1320

ucaucccaag gcaugcuccg caugucaccg gacgccauga acgcacuauu caaacccacu     1380

auagacucaa uaaucgaaca ccuacgcgac cucuuccaaa agcccgaagu aagcacaguc     1440

aaauuccucu uccucguggg cggguucgcc gaagccccac uccuccaaca ggccguccag     1500

gccgcauucg gagaccagug ccguaucaua aucccacaag acguaggccu aaccauacuc     1560

aaaggcgcag uccuauucgg ccuagacccc gccgucauua agguccgccg uucccccuua     1620

acauacggag ucggcguccu uaaccgcuau gucgaaggaa aacacccacc cgaaaagcuc     1680

cuagucaagg acggcacccg auggugcacc gacgucuucg acaaauucau auccgcagac     1740

caaagcguug cacucggcga acuugucaaa cgaucauaca cccccgcgaa acccucacaa     1800

uuagucauag ucauaaacau cuacuccuca gaacacgaca acguuuccuu caucaccgac     1860

cccggcguaa agaaaugcgg aacccucaga cuggaccuca ccggcacauc cggcacugcc     1920

guacccgcac gacgcgaaau acaaacccuc augcaguucg gcgacaccga aaucaaagca     1980

acugccaucg acauagccac aucaaaaucc guaaaaguag gaaucgacuu ccuaaacuac     2040

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  2274
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt9)

<400>  2274
gggagaaagc uuaccaugcu agcagucccc gaaaugggcc uacaaggccu cuacaucggc       60

uccagccccg aacguucacc cguacccuca ccaccaggcu caccaagaac ccaagaaagu      120

ugcggcaucg ccccacucac gcccucccaa ucccccaagc ccgaaguccg agcaccccaa      180

caggcuucau ucucugucgu cguagcaaua gacuucggaa ccaccucuag cggcuacgcu      240

uucucauucg ccagcgaccc cgaagccauc cacaugaugc gcaaauggga aggaggagac      300

cccgguguag cacaccagaa aaccccaacc ugccuacucc ucacacccga aggagccuuc      360

cacagcuucg gcuacaccgc ccgagacuac uaccacgacc ucgaccccga ggaggcucgu      420

gacuggcucu acuucgaaaa auucaaaaug aaaauccacu ccgccaccga ccucacccuc      480

aaaacucaac uagaagcggu uaacggaaaa acaaugcccg cccuagaagu uuucgcacac      540

gcccugcgcu ucuuccgaga acacgcacuc caagaacuuc gcgaacaaag cccgagccuu      600

ccugaaaaag acaccguucg augggucuug acaguccccg caauauggaa acaaccggcg      660

aaacaauuca ugcgagaagc agccuaccua gccggacugg uaucccgaga aaacgccgag      720

caacuacuca ucgcacucga acccgaagcu gcauccgucu acugccgcaa acuacgccuc      780

caccaacucc ucgaccuguc cggccgcgca ccaggaggcg guagauuggg ugagcgacgc      840

aguauagaca guuccuuucg acaagcacgc gaacagcuac gccgaagccg gcacucccga      900

acuuuccuug uagaaucagg cgucggcgaa cucugggccg aaaugcaagc aggagacaga      960

uacguaguug cggacugcgg cggcggcacc guugaccuga caguccacca auuagaacaa     1020

ccacacggca cucucaaaga acuuuacaaa gcauccggcg gacccuaugg cgccguagga     1080

gucgacuuag cauuugaaca acuccugugc agaaucuucg gggaagacuu uauagcaacc     1140

uucaaaagac aaagacccgc agccuggguc gaccuuacca ucgcauucga agcacggaaa     1200

cgaacagccg gcccacaccg agcaggagcc cugaacauca gccuaccauu cucauucauc     1260

gauuucuacc ggaaacaacg cggccacaac gucgaaacag cccuccggcg aagcagcguc     1320

aacuucguca aauggucauc ccaaggaaug cuacgaaugu ccugcgaagc aaugaacgaa     1380

cucuuccaac caaccgucuc gggcaucauc caacacaucg aagccuuacu agcccgccca     1440

gaaguacaag gagucaaacu ccucuuccua gucggaggcu ucgcagaguc cgcaguccua     1500

caacacgcgg uucaggccgc cuuaggagca cgcggccucc gagucguggu accccacgac     1560

guaggccuca caauccuaaa aggcgccguu cucuucgggc aagcucccgg cgucguacgc     1620

guacgccgca gcccacuaac cuacggcguu ggcguacuca accgcuucgu cccgggaaga     1680

cacccacccg aaaaacuccu aguccgagac gguagacgcu ggugcaccga cgucuuugaa     1740

agauucgugg ccgccgaaca aucagucgcc cucggcgaag aaguccgacg cagcuacugc     1800

cccgcacgcc ccggccaacg acgcguccuc aucaaccuau acugcugcgc agcagaagac     1860

gcacgcuuua uaaccgaccc cggcguccga aaaugcggcg cacucucacu cgaauuagaa     1920

cccgcagacu gcggucaaga caccgccgga gccccgcccg gaagacgaga aauccgcgcc     1980

gcaaugcaau ucggcgacac cgaaaucaaa gucacagccg ucgaugucuc cacaaaccga     2040

agcguaaggg ccucgauaga cuuccuaagu aacuagggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  2275
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt9)

<400>  2275
gggagaaagc uuaccauggc aagagaaaug acaauccuug gcuccgccgu gcuaacccuc       60

cuacuagccg guuaccucgc ccaacaguac cuaccccucc ccaccccaaa agucaucgga      120

aucgaucucg gcaccaccua cugcucaguc ggcgucuucu uccccggcac cggaaaagua      180

aaaguuauac cggacgaaaa cggccacauc uccauccccu caauggucuc cuucaccgac      240

aacgacgucu acgucggcua cgaaagcgug gaacucgccg acuccaaccc ccaaaauaca      300

auauacgacg ccaaacgcuu caucggcaaa aucuucaccg ccgaagaacu cgaagccgaa      360

auaggccgcu acccuuucaa agugcucaac aaaaacggca uggucgaguu cuccgucacc      420

agcaacgaaa caauaacagu aucgccagaa uacgucggcu cccgccuccu ccuuaaacua      480

aaagaaaugg cagaagccua ccuaggcaug cccgucgcca acgcaguaau cucaguccca      540

gccgaguucg accuuaaaca aaggaacucc accaucgaag cagcuaaccu cgccggccug      600

aaaauccucc gagucaucaa cgaacccacc gccgcggcca uggcauacgg acuucacaaa      660

gccgacgucu uccacguccu cguaaucgac cugggcggcg gcacccuaga cgucagccuu      720

cucaacaaac agggaggcau guuccucaca cgcgcgaugu caggaaacaa caaacuagga      780

ggccaggacu ucaaccaacg ccuacuccaa uaccuauaca aacaaauaua ccaaaccuac      840

ggauucguuc caucccgaaa agaagaaauc cacagacucc gacaagcagu agaaauggua      900

aaacucaacc uaacccuaca ccaauccgca caacuaagcg uccuccuuac aguagaagaa      960

caagaccgaa aagaaccaca cuccuccgac accgaacucc ccaaggauaa gcuauccagc     1020

gcugacgacc acagaguaaa cuccgguuuc ggccguggcc ucagcgacaa gaaaucuggu     1080

gaaucacagg uccuauucga aaccgagaua ucccgaaaac ucuucgacac ccucaacgaa     1140

gaccucuucc agaaaauccu cguccccauc caacaagucc ucaaagaagg ccaccucgag     1200

aaaacagaaa ucgacgaagu cguacucgua ggaggcucca cacgcauccc ccgcauccga     1260

caaguaaucc aagaguucuu cggcaaagac cccaacaccu caguagaccc ugaccuggcc     1320

gucguaaccg gagucgccau ccaggccgga auugauggcg gauccuggcc ccuacaagug     1380

agcgcccucg aaaucccaaa caaacaccuc cagaaaacaa acuuuaacug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2276
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt9)

<400>  2276
gggagaaagc uuaccauggc cgcaauaggc guccaccuag gcugcaccag cgccugcguc       60

gccgucuaca aagacggcag agcaggcgua gucgccaacg acgccggaga ccgcgucacc      120

ccagcagucg ucgccuacag cgagaacgaa gaaaucgugg ggcucgcagc caaacaaucc      180

cgcauccgaa auaucuccaa cacagucaug aaaguaaaac aaauccuagg acgcaguucg      240

ucagaucccc aggcccaaaa auacauagcc gaaucaaaau gccuaguaau agagaaaaac      300

ggcaaacucc gauacgaaau cgacaccggu gaagaaacaa aauucguaaa cccagaagac      360

gucgcacgcc uaauauucag caagaugaaa gaaaccgccc acucugugcu cggaagugac      420

gccaacgacg uagucaucac cguaccauuc gacuucggcg aaaaacagaa aaacgcccua      480

ggcgaagccg caagagccgc cgguuucaac guccugcgac ucauacacga accaagcgcc      540

gcgcuccucg ccuacggcau cggccaagac uccccaaccg ggaaguccaa cauccuagua      600

uucaagcuag gaggcaccag ucuaucccua uccgucaugg aagucaacag cggcauauac      660

cgcguacucu caaccaacac agacgacaac aucggcggag cccauuucac cgaaacacua      720

gcccaauacc ucgccuccga guuccaacgc ucuuucaaac acgacguccg cggcaacgcg      780

cgcgccauga ugaaacuaac caacagcgcc gaaguagcua aacacucacu cucaacacuc      840

ggcuccgcaa acugcuuucu ugacagccua uacgaaggcc aagacuucga cugcaacguc      900

ucaagagcca gguucgaacu acuaugcuca ccacucuuca acaaaugcau cgaagccaua      960

cguggacuac ucgaccaaaa cggauucacu gccgacgaca ucaauaaagu aguacucugc     1020

ggaggaucuu cacgaauacc uaaacuacaa caacucauca aagaccucuu cccagccguc     1080

gaacuucuua acuccauccc acccgacgaa gucaucccca ucggcgccgc caucgaagcc     1140

ggcauccuca ucggaaaaga aaaccuacuu guagaggacu cccucaugau cgaaugcucc     1200

gccagagaca uccuagucaa aggcguagac gagagcggcg ccagccgauu caccguccua     1260

uuccccuccg gaacaccacu accagcccga cgccaacaca cacuacaagc cccaggauca     1320

auauccuccg ucugccucga acucuacgaa agcgacggca aaaacuccgc aaaagaagaa     1380

accaaauucg cacaagucgu ccuccaagac cucgacaaga aagaaaacgg ccuccgcgac     1440

aucuuagcag ugcucaccau gaaacgcgac ggcagccugc acguaacaug cacagaccag     1500

gaaaccggca aaugcgaagc caucuccaua gaaaucgccu cauaaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  2277
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt9)

<400>  2277
gggagaaagc uuaccaugag cguaguagga cucgacguag ggagccaauc cugcuacaua       60

gccgucgccc gcgccggugg caucgaaacc aucgcaaacg aguucaguga ccgaugcacc      120

cccuccguaa uauccuucgg aagcaaaaac agaaccauag gcguagcugc uaaaaaucag      180

caaaucacac acgcgaauaa cacggucuca aacuucaaac gauuccacgg cagagccuuc      240

aaugaccccu ucauccaaaa agaaaaagaa aaccuaucau acgaccuagu accccucaaa      300

aacggaggcg uaggaaucaa agucauguac augggagaag aacaccuauu cagcguagaa      360

caaauaacug ccaugcuacu caccaaacuc aaggaaaccg cagaaaacuc acugaaaaag      420

ccagucaccg acugcgugau aagcgucccc ucuuucuuca ccgacgccga acgccgaucg      480

guccuagacg cagcccaaau agucggccua aacugucuac gacuaaugaa cgacaugaca      540

gcaguggccc ugaacuacgg caucuauaag caagaccugc ccucgcucga cgaaaaacca      600

cgcaucguag uauucgucga uaugggccac ucagcauucc aagugucagc cugcgcauuc      660

aacaagggca aacucaaagu gcuaggcacc gccuucgacc ccuuucucgg aggcaaaaac      720

uucgacgaaa agcuagugga acacuucugc gcagaauuua aaaccaaaua uaaacucgac      780

gccaaaucca aaaucagagc ccugcuacga cucuaccaag aaugcgaaaa acuaaagaaa      840

cugauguccu ccaacucaac cgaccugccc cugaacaucg aaugcuucau gaacgacaaa      900

gacgucuccg ggaaaaugaa cagaucacaa uucgaagaac uuugcgccga acuacuccag      960

aaaaucgaag uaccacucua cucccuccug gaacaaaccc accuaaaagu cgaagacgug     1020

uccgccguag aaauugucgg cggcgcaaca cgcauaccgg ccguaaaaga acgaauagcg     1080

aaauucuucg gcaaagacau cuccaccacc cuuaacgcag acgaagccgu cgcacgcggc     1140

ugcgcccucc agugcgcaau acucucgccg gccuucaaag uccgcgaguu cuccgucacg     1200

gaugccgucc cauucccgau cucccugauu uggaaccacg acagcgaaga cacugaagga     1260

guccaugagg uauucagccg aaaccacgca gcucccuuca gcaaaguacu cacauuccua     1320

cgccgcggac cauucgaacu ggaagcguuc uacagugacc cccagggagu accguacccg     1380

gaagcaaaaa ucggacgcuu cguggugcaa aacguaucag cacaaaagga cggcgagaaa     1440

agccgcguca aaguaaaagu aagaguaaau acgcacggaa ucuucacaau cucaacagcc     1500

ucaauggucg aaaaaguacc caccgaggaa aacgaaauga gcuccgaagc cgauauggaa     1560

ugccucaacc aacgcccacc cgaaaacccc gauacagaca agaacgucca acaagacaau     1620

uccgaagcgg gcacacaacc ccagguccaa acagacgcac agcaaacaag ccagucccca     1680

cccucacccg agcucaccuc ggaagagaac aaaauacccg augccgacaa agcuaacgag     1740

aaaaaggugg accaaccacc cgaagccaag aaacccaaaa ucaaagucgu uaacguagaa     1800

cuaccaauag aagccaaucu uguauggcag cucgggaaag accuccugaa uauguacauc     1860

gaaacagaag gcaaaaugau caugcaggac aaacucgaaa aagaacgaaa cgaugccaaa     1920

aacgccgucg aagaauacgu auacgaguuc cgagacaaac uaugcggccc cuacgaaaag     1980

uucaucugcg aacaagacca ucaaaacuuc cuccgacucc ucaccgaaac agaagacugg     2040

cuauacgaag aaggcgaaga ccaagccaag caggcguacg uagacaaacu agaggaacua     2100

augaaaaucg ggaccccugu aaaaguacga uuccaagaag ccgaagaacg accaaaaaug     2160

uuugaagaac ugggacagcg ccuccagcac uacgccaaga ucgccgcaga cuuccgcaau     2220

aaagacgaaa aauacaacca uauagacgaa agcgaaauga aaaaggucga aaagagcguc     2280

aacgagguca uggaauggau gaacaacguc augaacgcuc aagccaagaa aagucuagac     2340

caagaccccg uagugagggc gcaagaaauc aaaaccaaaa uaaaagagcu gaacaacaca     2400

ugugaaccag ucgucacgca accgaaacca aaaaucgaaa gcccgaaacu cgagcgcaca     2460

cccaacggac ccaacaucga caagaaagaa gaagaccuag aagacaaaaa caacuucggu     2520

gccgagcccc cgcaccaaaa cggugaaugc uaucccaacg agaaaaacag cgugaacaug     2580

gaccuugacu aaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  2278
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt9)

<400>  2278
gggagaaagc uuaccauggc agacaaagug agacgacaac guccgcgucg gcggguuugc       60

ugggcacucg uggcaguccu ccuagcagac uugcucgccc uaagcgauac ccuagcagug      120

augucuguag acuuaggauc ggaaucgaug aaaguagcca ucgucaaacc gggagugcca      180

auggaaaucg uacuaaacaa agaaucacgc aggaaaaccc ccgugaucgu cacgcugaaa      240

gagaaugagc gauucuucgg cgauuccgca gcauccaugg cgaucaaaaa cccgaaggca      300

acacugagau acuuucagca ccuccucgga aaacaggcag acaacccaca cguagcccuc      360

uaccaagcac gcuuccccga gcacgaacua acauucgacc cccaacgcca aaccgugcac      420

uuccaaauca gcagucagcu ccaauuuagc ccagaagagg uacucggaau gguacucaac      480

uacuccagga gccucgcuga agauuuugcc gaacagccca uaaaagacgc agucauaaca      540

guacccgucu ucuucaacca agccgaaaga cgagcgguac uccaagcagc aagaauggcc      600

ggccucaagg uccuucaacu gaucaacgac aacacagcga cagcacucuc cuacggagua      660

uucagaagaa aagacauaaa caccacagca cagaacauca uguucuacga caugggaagc      720

ggaaguacug uuugcacaau aguaaccuac caaaugguaa agaccaaaga ggcaggaaug      780

caaccacaac uucaaauacg aggggucggc uuugacagga cucuaggagg acuggagaug      840

gaacuccggc uucgagaacg ccuagcagga cucuucaacg aacaacgaaa gggccagaga      900

gccaaagacg uacgagaaaa uccacgagca auggccaaac uccuaagaga agcgaaccga      960

cucaaaacgg uccuaagcgc aaacgcggac cacauggccc aaaucgaagg acuaauggac     1020

gacguugacu ucaaagccaa aguaacacga guagaguuug aagaacucug cgccgaccuc     1080

uucgaacgag ugccaggacc gguacaacaa gcacuccaga gcgcagaaau gucccuagac     1140

gaaaucgagc aagugauccu aguaggaggc gcaacccggg uaccacgcgu acaagaagua     1200

uuacugaaag cggugggaaa agaagaguua gggaaaaaca uaaacgccga cgaagccgca     1260

gcaaugggag caguauacca agccgcggcc cucagcaaag ccuucaaagu aaaacccuuc     1320

guagugcggg acgcagucgu auacccaaua cugguggagu uuaccagaga agucgaagag     1380

gaacccggca uccacagccu aaaacacaac aaaagagucc uguucuccag gaugggaccc     1440

uacccacaac gcaaggugau aacauucaac cgauacaguc acgacuuuaa cuuccacaua     1500

aacuaugggg accugggcuu ccuaggaccc gaggaccucc gcgucuucgg aucccaaaac     1560

cuaacaaccg uaaaacucaa aggaguagga gacucuuuca aaaaguaccc cgacuacgaa     1620

ucaaagggga uaaaagccca cuuuaaccuc gacgaaagug ggguccucag ccuggaccgc     1680

guagagucgg ucuucgaaac acucgucgaa gacagugccg aagaagaauc aacccuaacg     1740

aaacuaggca acacaauauc aagccucuuc ggaggaggca caacaccuga cgccaaagaa     1800

aacggaacag acaccguaca agaagaagag gaaagccccg cggagggauc aaaagacgaa     1860

ccaggcgaac agguggaacu caaagaagaa gcggaagccc cagucgagga uggaagccaa     1920

cccccaccac ccgaaccgaa aggcgacgca acaccggaag gcgaaaaggc caccgagaaa     1980

gaaaacgggg acaagucaga agcccaaaag ccaagugaaa aagccgaagc aggcccagaa     2040

ggaguagccc cggccccaga aggagagaaa aagcagaaac ccgccaggaa acgccgaaug     2100

guggaggaga uaggcgucga acucguagua cuggaucuac cagaccuccc cgaagauaag     2160

cuagcacaaa gcgugcaaaa acuccaggac cucacccugc gcgacuuaga aaaacaagag     2220

agagagaaag cagcaaacag ccuggaggcc uucaucuucg aaacacaaga caagcuguac     2280

cagcccgaau accaagaagu gagcacggaa gaacaaagag aagagaucuc cggcaagcua     2340

uccgcagcca gcacguggcu cgaagacgaa ggaguagggg ccacaacagu uaugcucaaa     2400

gaaaaauuag cagaacuaag aaagcuaugc caaggacuau uuuucagagu ggaagagaga     2460

aagaaauggc cggaaaggcu cagugcccuc gacaaccuac ucaaccauuc cagcauguuc     2520

cugaagggcg caaggcuaau accagaaaug gaccaaauau ucacagaagu agaaaugacc     2580

acucucgaga aaguaauaaa cgagacaugg gcguggaaaa acgcaacccu cgcagaacaa     2640

gcgaagcugc cagccacgga gaagccgguu cuacucagca aggauauaga agcaaagaug     2700

auggcacuag acagagaagu ccaguaccug uuaaacaaag caaaauucac aaaaccacgc     2760

ccaaggccga aagacaaaaa cggaacacga gcagaaccac cacugaacgc gucagcuuca     2820

gaccaaggag aaaaaguaau acccccagca gggcaaaccg aggacgcaga accaaucagu     2880

gaaccagaga aaguugagac gggaagcgaa ccaggagaca cggaacccuu agaauuagga     2940

ggcccaggcg cagaaccaga acaaaaagag caaagcacug gccaaaagcg uccccucaaa     3000

aacgacgagc uaugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2279
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt9)

<400>  2279
gggagaaagc uuaccaugcc cgaagagacg caaacgcaag aucaaccgau ggaggaggaa       60

gaaguggaaa ccuucgcguu ccaggcagaa aucgcgcaac ugaugagccu cauaaucaac      120

acguuuuaca gcaacaaaga aauauuccug cgcgagcuaa uaagcaacag cagcgacgca      180

cucgacaaga uacguuacga aucccuaacg gacccgagca aacuagacag cgggaaggaa      240

cuacacauca accucauccc caacaagcag gaccgaaccc ugaccauagu cgacaccgga      300

auagggauga cgaaagcaga ccucaucaac aaccucggaa cgaucgccaa aagcggcacg      360

aaggcuuuca uggaagcacu acaagcgggc gccgacauaa guaugauagg ccaauucgga      420

guaggauucu acagugccua ccuaguggca gagaaaguca ccguaauaac aaaacacaac      480

gacgacgaac aauacgccug ggaaagcagc gccgggggcu ccuuuacagu aagaacagac      540

accggagaac caaugggccg cggaacaaaa guaauacucc accuaaaaga ggaccaaaca      600

gaauaccucg aggaaagacg aauaaaggag aucgucaaaa agcacagcca auucauagga      660

uacccaauaa cgcuauucgu ggaaaaagaa cgagacaaag aagugucaga cgacgaagcg      720

gaggaaaaag aggauaagga agaagagaaa gagaaagaag aaaaagaaag cgaagacaag      780

ccagaaaucg aggacguagg gucggacgaa gaggaggaaa agaaagacgg cgauaagaaa      840

aagaaaaaga aaaucaaaga aaaguacauc gaccaagagg agcuaaacaa aacaaaaccg      900

aucuggacac gaaacccaga cgacaucacg aacgaggaau acggcgaguu cuacaaauca      960

cucacaaacg acugggaaga ccaucuagca guaaagcacu ucagcgucga aggccaacug     1020

gaguucagag cucuccuguu cguacccagg cgcgcccccu ucgaccucuu cgaaaacaga     1080

aagaagaaaa acaacauaaa auuauacgua agacgaguau ucauaaugga caacugcgaa     1140

gaacugaucc cggaauaccu caauuucauc cgcggagucg uagacagcga ggaccuacca     1200

cuaaacauaa gcagagagau gcuacagcag aguaaaaucc uaaaaguaau acggaaaaac     1260

cuugucaaaa agugccugga gcuauucacc gaacuugcag aggacaaaga aaacuacaag     1320

aaguucuacg agcaguucag caagaauaua aaacuaggca uacacgaaga cucacagaac     1380

cgcaagaaac uaagcgaacu ccugagauac uacaccagcg ccagcgggga cgagaugguc     1440

agccuaaaag acuacugcac aagaaugaaa gaaaaccaaa aacacaucua cuauaucacg     1500

ggagaaacaa aagaccaggu cgcgaacuca gccuucgucg agcgacuccg caaacacggg     1560

cucgaaguaa ucuauaugau agagcccauu gacgaguacu gcguacagca acuaaaagag     1620

uucgaaggaa aaacccucgu aagcgucacg aaagaaggcc uagaacugcc cgaagacgaa     1680

gaggagaaaa agaaacaaga agaaaagaaa acaaaauucg aaaaccugug caaaaucaug     1740

aaagacaucc uggagaagaa aguggagaaa guagucguaa gcaaccgccu aguaacgagc     1800

ccaugcugca uagucacaag cacauacgga uggacggcga acauggagcg aauaaugaaa     1860

gcccaagccc ugcgagacaa cagcacaaug ggauacaugg cggccaaaaa gcaccuagaa     1920

aucaaccccg accacuccau caucgaaaca cucagacaaa aagccgaagc cgacaaaaac     1980

gacaaaagcg uaaaggaccu ggugauacuc cuuuacgaaa ccgcccugcu cucaagcggc     2040

uucucccugg aggacccaca gacccacgcg aacagaaucu acagaaugau aaagcugggc     2100

cuaggaauag acgaagacga cccaacagcc gacgacacau ccgcagccgu caccgaagaa     2160

augccacccc uagaagggga cgacgacaca agcagaaugg aagaaguaga cuaaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  2280
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt9)

<400>  2280
gggagaaagc uuaccaugga cucaucaaaa cuagacuccg gcaaaggccu acacauaaac       60

cucgucccca acaaacaaaa ccaaacccuc accaucguag acacacgcau cggcaugacc      120

aaaaccgacc ucaucaacaa ccucggaacc gucaccaaau ccggcacaaa agccuucaug      180

gaagcccucc aagcagacgc agacauaucc augaucggcc acuucggagu aggcuucuac      240

uccgccuacc ucgucgccaa aaaagucacc gucaucucaa aacacaacaa cgacgaacaa      300

uacaccuggg aauccuccgc aggaggcagc uucaccgucc gcaccgacga auaaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  2281
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt9)

<400>  2281
gggagaaagc uuaccaugcc cgaggaagua caccacggag aagaggaagu cgaaaccuuc       60

gccuuccaag cggaaaucgc ccaacuaaug agcuugauaa uaaacacguu cuacuccaac      120

aaagagauau uccugcggga gcuaauaucg aacgccagcg acgcccuaga caagaucagg      180

uacgaguccc ucaccgaccc cagcaaacua gacucgggca aggaacugaa aaucgacaua      240

aucccgaacc cgcaagagcg cacccucacc cuaguggaca cgggaauagg caugaccaaa      300

gcagaccuca uaaacaaccu cggcaccaua gccaagagcg gaaccaaggc cuucauggaa      360

gcacugcaag caggagcaga cauaaguaug aucgggcaau uuggcguagg guucuacuca      420

gcguaccucg ucgccgaaaa aguaguaguc auaacgaaac acaacgacga cgagcaauac      480

gcgugggagu caagcgcagg agggagcuuc accguacggg cagaccaugg cgaacccaua      540

ggcagaggca ccaaaguaau ccuccaccua aaggaagacc aaacagagua ccuagaagaa      600

cggagaguaa aagaagucgu caagaaacac ucccaauuca uaggcuaucc caucacacua      660

uaccucgaga aagaacgaga aaaagaaaua uccgacgacg aagccgaaga agaaaaaggg      720

gaaaaagaag aggaagacaa agacgacgaa gaaaagccca aaauagaaga cguuggcucg      780

gacgaggagg acgacagcgg caaagacaag aaaaagaaaa cgaagaaaau aaaagagaaa      840

uacaucgauc aagaagaacu caacaaaacc aaaccgaucu ggacacggaa ccccgacgau      900

aucacgcaag aggaguacgg cgaguucuac aaaucacuaa cgaacgacug ggaagaccac      960

cucgcgguca agcacuucag uguggaaggc caacuagagu uccgagcgcu auuguucauc     1020

ccaagacgcg cacccuucga ccucuucgaa aacaaaaaga agaaaaauaa cauaaaacug     1080

uacguacgac ggguguucau cauggacagc ugcgacgaau ugauaccgga auaccugaac     1140

uucauccgag gagucgugga cucagaagac cucccacuaa acaucucccg agaaaugcuu     1200

caacagagca aaauccuaaa agugaucagg aaaaacaucg uaaagaaaug cuuagaacua     1260

uucagcgaac uagcagagga caaagaaaac uacaagaaau ucuacgaagc cuucagcaaa     1320

aacuugaaac uaggcauaca cgaagacagc acgaaccgaa ggcgcuuguc cgaacuacua     1380

cgcuaccaca cgucccagag cggcgacgag augaccagcc ugagugaaua cgugagccgc     1440

augaaagaaa cgcagaaaag cauauacuac auaacaggcg aaagcaaaga acaaguagcg     1500

aacagugccu uugucgaaag aguacgaaaa cgcggauucg aggucguaua caugacggaa     1560

ccaauagaug aguacugcgu ccaacaacua aaagaguucg acgggaaaag ccuagucagu     1620

guuacgaaag agggccucga acuacccgaa gacgaggagg agaaaaagaa aauggaagaa     1680

agcaaagcaa aauucgaaaa ccugugcaag cucaugaaag aaauauugga caagaaaguc     1740

gaaaaaguaa cgaucucgaa ucgacucgua ucaucccccu gcugcauagu cacgagcaca     1800

uacggaugga cagcgaauau ggagcggauc augaaggcac aagcccuacg cgacaacagc     1860

accaugggcu acaugauggc gaagaaacac cucgagauaa acccagacca cccgaucgug     1920

gagacgcuaa gacagaaagc agaagccgac aaaaacgaca aagccguaaa agaccuagua     1980

guacugcuau ucgaaacagc ccugcucagc agcggauucu cacucgaaga cccgcaaacc     2040

cacagcaacc gaaucuaccg caugaucaag cucggacucg gcaucgacga agacgaagua     2100

gccgccgaag aaccgaacgc agccgucccu gacgagauac cgccccucga aggcgacgag     2160

gacgcaagcc gaauggagga aguagacuaa ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  2282
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt9)

<400>  2282
gggagaaagc uuaccaugcg agccuuaugg guccucggac ucugcugcgu gcuacugacc       60

uucggcagcg uaagagcaga cgacgagguc gacguagacg gcacgguaga ggaagaccuc      120

ggcaaaucgc gagaaggcuc acgcacagac gacgaaguag uccagcgaga agaagaagcg      180

auacaacuug acgggcugaa cgcgagccag auccgcgaac ucagggagaa aagugaaaaa      240

uucgcauuuc aggcagaagu uaacaggaug augaagcuaa ucauaaauuc ccuguacaaa      300

aacaaagaga ucuuccuacg ggaacuaaua ucaaacgcca gcgacgcucu agacaaaauc      360

agacuaauaa gccuaacaga cgaaaacgca cuaagcggaa acgaagaauu gacagucaaa      420

aucaagugcg acaaagagaa aaaccugcug cacgucaccg acacaggcgu gggcaugacc      480

cgagaggaac ucgucaaaaa ccugggaacg auagcaaagu cagggaccag cgaguuccuc      540

aacaaaauga cagaagccca ggaggacggg cagagcacga gcgaacugau agggcaauuc      600

ggaguaggau ucuacagcgc guuccuggua gcggacaaag ucauagucac cagcaaacac      660

aacaacgaua cccagcacau cugggagagc gacaguaacg aauuuagcgu aaucgcagac      720

ccucgaggca acacacuagg gcgagggacc acaauaacac ugguacuaaa ggaagaagcc      780

agugacuacc ucgagcuaga uaccaucaag aaucucguaa agaaauacuc acaauucauc      840

aacuucccaa ucuacgucug gagcagcaaa acagaaacgg uugaagaacc uauggaggaa      900

gaggaagcgg caaaagagga aaaggaagaa ucagacgacg aggccgccgu ggaagaggaa      960

gaagaggaaa agaaaccaaa aacgaagaaa guggagaaaa caguauggga cugggaacug     1020

augaacgaca ucaagcccau auggcaaaga ccaagcaagg aaguagaaga agacgaguac     1080

aaggcguucu acaaaaguuu cuccaaggag ucagacgacc ccauggcaua uauacacuuc     1140

acggcagagg gcgaagucac auucaagagc auacucuucg ugcccaccuc ggcaccacgc     1200

ggacuauucg augaguacgg gagcaagaaa agcgacuaca uaaaacuaua cgucaggagg     1260

guauucauaa cggacgacuu ccacgacaug augcccaagu accugaacuu cgucaaggga     1320

guagucgaua gcgaugaccu accccugaac guaagcaggg aaacccuaca acaacacaaa     1380

cuucucaaag uaauccggaa aaagcucgug aggaagaccc uagacaugau aaagaaaaua     1440

gcggacgaca aauacaacga cacauucugg aaagaguucg ggacaaacau aaaacuaggu     1500

gugauagagg accacagcaa caggacgaga cuggccaaac uccuacgauu ccaaucaagc     1560

caucacccca cagacaucac gagccuagac caguacguag aaagaaugaa ggaaaaacag     1620

gacaaaauuu acuucauggc aggguccagc agaaaagagg ccgaaagcuc ccccuucguc     1680

gaaaggcugc ucaagaaagg guaugaaguc auauaccuaa cagagccagu cgaugaauac     1740

ugcauacagg cacugccaga guuugacggc aagagauucc aaaacgucgc aaaagaagga     1800

gugaaauucg acgaaaguga gaagaccaaa gagagcagag aagccgucga gaaagaguuc     1860

gaaccucucc ucaacuggau gaaagacaaa gcgcuaaaag acaagauaga aaaagcaguc     1920

guaagccaac gacucacaga aagcccaugc gcgcuagucg ccucgcaaua cggaugguca     1980

gggaacaugg aaagaaucau gaaagcgcaa gcguaccaaa cugggaaaga cauauccacg     2040

aacuacuacg ccagccaaaa gaaaacguuc gaaaucaacc ccaggcaucc acugauaagg     2100

gauaugcuac gcagaauaaa agaagacgag gacgacaaaa caguccucga ccucgcaguc     2160

guccucuucg aaacggcaac ccuuagaagc ggcuaccugc ugccagacac caaagccuac     2220

ggagacagga ucgagcgaau gcuacgacuc ucacuaaaca uagacccgga cgcaaaagua     2280

gaggaagaac cggaggagga gccagaagaa acagccgaag auacaacaga ggacacggaa     2340

caagacgaag acgaagaaau ggacguaggu acagacgagg aagaagaaac agccaaagag     2400

agcacagcgg agaaggacga gcuauaggga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  2283
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt9)

<400>  2283
gggagaaagc uuaccauggc ccgagaauua agagcccuau uacucugggg acgucgucuc       60

cguccccucc uccgcgcacc agcccuagca gccguacccg gcggcaaacc cauucucugc      120

ccaagaagaa ccacugccca gcuagggccc cgacgaaacc ccgcgugguc gcuccaagcu      180

ggacgacucu ucucaaccca aaccgcagaa gacaaagaag aaccccucca cagcaucaua      240

ucuucaacag aauccgucca agguagcaca uccaaacacg aguuccaagc cgaaaccaag      300

aaacuguuag auaucgucgc ccgcucccuc uacagcgaaa aagaagucuu cauccgcgaa      360

cugaucucaa acgccagcga cgcccuagag aaacuacgcc auaagcuagu cucagacggc      420

caagcacuac ccgaaaugga aauucaccuc caaaccaacg ccgaaaaagg caccauaaca      480

auccaagaca ccggaaucgg caugacccaa gaggaacucg uaagcaaccu cggcacuauc      540

gcgcgcucag ggucaaaagc auuccuagac gcuuuacaaa accaggccga ggcuucaucc      600

aaaauaaucg gccaauucgg cguaggcuuc uacucagccu ucauggucgc ggaucgcguc      660

gaagucuacu cccgcagcgc agccccaggg agccuagggu accaguggcu cagcgacggc      720

uccggcguau ucgaaaucgc cgaagccucc ggagucagaa caggaaccaa aaucauaauu      780

caccugaaau cugacugcaa agaguucagc uccgaagcac gcguucgaga cguagucaca      840

aaauacucca acuucgucuc cuucccacuc uaccucaacg gaagacgcau gaacacccuc      900

caggccaucu ggaugaugga ccccaaggac guccgugaau ggcaacacga agaguucuac      960

cgauacgugg cacaagccca cgauaaacca cguuacaccc uacacuacaa aaccgacgcc     1020

ccacucaaca ucagaagcau cuuuuacguc cccgacauga aaccgucaau guucgacguc     1080

ucccgugaac uaggauccuc cgucgcacuc uacucacgca aaguccuaau ccaaacuaaa     1140

gccacagaca uccuucccaa auggcuccgg uucauacgcg gcgucgugga cucagaagac     1200

aucccccuaa accucucccg cgaacuacuc caagaauccg cgcuaauccg aaaacuuaga     1260

gacguacuac aacaacggcu aaucaaauuc uucaucgacc agaguaagaa agacgccgaa     1320

aaauacgcua aauucuucga agacuacgga cuauucaugc gagaaggcau cgucaccgcc     1380

accgaacaag aagucaaaga agauaucgca aaacuccuac gcuacgaguc uuccgcccua     1440

cccucaggac aacuuaccuc acuaagcgaa uacgccagcc gcaugcgcgc gggcacacgg     1500

aauauauacu accuaugcgc acccaaccga caucucgccg aacacagccc auacuaugaa     1560

gccaugaaga agaaagacac ugaaguccua uucugcuucg aacaauuuga ugagcucacc     1620

cuacuacacc uccgggaauu ugacaaaaag aaacuaauau ccgucgagac cgacaucguc     1680

guagaccacu acaaagagga aaaauucgag gaccgcuccc cagcagccga gugccuaagc     1740

gaaaaagaaa ccgaagaacu aauggccugg augcgcaacg uucuaggcuc aagaguaacc     1800

aacguaaaag uaacccuacg acucgacacc caccccgcca ugguaaccgu acucgaaaug     1860

ggagcagccc gccacuuccu acgaaugcaa caacucgcca aaacacagga ggaacgagcc     1920

cagcuccuac agccaacacu cgaaaucaac ccccgacacg cacucaucaa gaaacucaac     1980

caacuccggg cauccgaacc aggacucgcc cagcuccuag uagaccagau cuaugaaaac     2040

gccaugaucg cugcaggccu agucgacgac ccaagagcaa ugguuggacg acuaaacgaa     2100

cugcucguca aagcccucga gcgccacuaa ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  2284
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt9)

<400>  2284
gggagaaagc uuaccauggg caaaaucucc ucccuaccca cccaacuauu caaaugcugc       60

uucugcgacu uccuaaaagu caaaaugcac acaauguccu caucccacuu auucuaccuc      120

gcacucugcc uccucacauu caccucaucc gccaccgcag gccccgaaac ccuaugcggc      180

gccgaacucg ucgacgcacu ccaauucguc ugcggcgacc gcggcuucua cuucaacaaa      240

cccacaggcu acggcuccuc cucaagacga gcaccccaaa ccggcaucgu agacgaaugc      300

uguuuccgau caugcgaccu ucgccgccuc gaaauguacu gcgcaccccu caaacccgcc      360

aaaucagccc gcuccguccg ugcccaacga cacaccgaca ugcccaaaac ccaaaaagaa      420

guccaccuca aaaacgccuc ccgcggcucc gcaggcaaca aaaacuaccg cauguaagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  2285
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt9)

<400>  2285
gggagaaagc uuaccauggg aauccccaug ggcaaaucaa ugcucguccu ccucaccuuc       60

cucgccuucg ccuccugcug cauagccgcc uaccgacccu ccgaaacacu cugcggcgga      120

gaacucgucg acacccuaca auucgucugc ggcgaccgag gcuucuacuu cucccgaccc      180

gccucacgag uaucccgccg cucccgcggc aucgucgaag aaugcugcuu ccgcucaugc      240

gaccucgccc uccucgaaac cuacugcgcc accccagcca aauccgaacg agacgucucc      300

accccaccca caguacuucc cgacaacuuu ccccgauacc ccguaggcaa auucuuccaa      360

uacgacaccu ggaaacaauc aacccaacga cuccgccgug gccuccccgc ccuacuccgc      420

gcacgccgcg gacacguccu agcaaaagaa cucgaagccu uccgcgaagc caaacgacac      480

cgcccccuca ucgcccuccc cacccaagac cccgcccacg gaggcgcccc acccgaaaug      540

gccuccaacc guaaauaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  2286
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt9)

<400>  2286
gggagaaagc uuaccaugaa cuccuucucc accuccgccu ucggccccgu cgccuucucc       60

cucggccucc uccucguccu ccccgccgcc uuccccgccc ccgucccccc cggcgaagac      120

uccaaagacg ucgcugcccc ccaccgccaa ccccuaaccu ccuccgaacg caucgacaaa      180

caaauccgcu acauccuaga cggcaucucu gcacuccgaa aagaaaccug caacaaaucu      240

aacaugugcg aauccuccaa agaagcccua gccgaaaaca accucaacuu acccaaaaug      300

gccgaaaaag acggcugcuu ccaauccggc uucaacgaag aaaccugccu cgucaaaauc      360

aucaccggcc uccucgaauu cgaagucuac cucgaauacc uacaaaaccg auucgaaucc      420

ucagaagaac aagcccgagc cguccaaaug uccaccaaag uccucaucca auuccuccaa      480

aaaaaagcca aaaaccucga cgccaucacc acaccugacc caaccaccaa cgccucacuc      540

cucacaaaac uccaagccca aaaccaaugg cuccaagaca ugacaacaca ccucauccuc      600

cgcuccuuca aagaauuccu ucaauccucc cucagagccc uccgccaaau guaaggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  2287
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt9)

<400>  2287
gggagaaagc uuaccaugcc ccuacucugg cuacgcggcu uccuacuagc aagcugcugg       60

aucauaguaa gaagcucacc caccccagga agcgaaggac acagcgccgc gccagacugc      120

ccaucaugcg cacucgccgc ccuccccaaa gacguaccca acagccagcc cgaaauggua      180

gaagcaguga aaaaacacau acuaaacaug cuccaccuaa aaaagcgacc cgacguaacc      240

caacccgucc caaaagcagc acuacuaaac gcaaucagaa aacuccacgu agggaaaguc      300

ggcgaaaacg gauacguaga aaucgaagac gacauaggaa ggcgcgccga aaugaacgaa      360

cucauggaac aaacgucgga aauaaucaca uucgcagaau cagguacggc cagaaaaacc      420

cuacacuuug agaucagcaa agaagggagc gaccuaagcg ucgucgaaag agcagagguc      480

uggcuguucc ucaaaguucc aaaagccaac agaacacgca caaaaguaac aauacgccua      540

uuccagcaac aaaaacaccc acaaggcagc cuagacaccg gagaagaggc cgaggaagua      600

ggacuaaaag gagaacggag cgaacuacua cuaagcgaaa aagucguaga cgcccgcaaa      660

agcacauggc auguauuccc cguaagcagc uccauacaac gacuccuaga ccaaggcaaa      720

ucaucacucg acguaagaau cgcgugcgaa caaugccaag aaagcggagc cagccuugua      780

cuacugggca agaaaaaaaa aaaagaagag gaaggcgaag ggaaaaaaaa aggcggcgga      840

gaaggaggcg ccggagcaga cgaagaaaaa gaacaaagcc acagacccuu ccuaaugcug      900

caagcacgac agagcgaaga ccacccccac cgcagacgcc gacgcggacu cgaaugcgac      960

ggaaaaguaa acaucugcug caagaaacaa uucuucguca gcuucaagga cauaggaugg     1020

aacgacugga uaauagcacc gagcggcuac caugcaaacu acugcgaagg cgaaugccca     1080

agccacaucg caggcacaag cggaagcagc cuaagcuucc acagcaccgu caucaaccac     1140

uacagaaugc gaggacacag cccauucgcc aaccugaaaa gcugcugcgu cccgacgaaa     1200

cuaagaccaa ugagcaugcu auacuacgac gacggccaaa acauaauaaa gaaagacaua     1260

caaaacauga uaguagaaga gugcggcugc agcuaaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  2288
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt9)

<400>  2288
gggagaaagc uuaccaugga cggccucccc ggccgagcac uaggcgccgc augccuccuc       60

cuacucgcag ccggauggcu uggccccgaa gcauggggcu ccccaacacc accucccacc      120

cccgcagcac cacccccacc cccaccaccc ggcucccccg gcggcagcca ggacacaugc      180

accucaugcg gcggcuuccg acgccccgaa gaacucggcc gcgucgacgg agacuuccuc      240

gaagccguaa aacgccacau ccuuucccgc cuccaaaugc gaggccgacc caacaucacu      300

caugccgucc ccaaagccgc cauggucacc gcccuacgca aacuccacgc cggcaaaguc      360

cgagaagacg gccgcgucga aaucccccac cucgacggcc acgccagccc cggcgccgac      420

ggccaagaac gaguuuccga aaucaucucc uucgccgaaa ccgacggccu ugcauccagc      480

cgaguacgcc ucuacuucuu caucucaaac gaaggcaacc aaaaccucuu cguaguacaa      540

gccucccuuu ggcucuaucu caaacuccua cccuacguac uagaaaaagg cucucgccgc      600

aaaguaagag ucaaagucua cuuccaagaa caaggccacg gcgaccgaug gaacaugguc      660

gagaaacgcg ucgaccuaaa acgcuccggu uggcacacau ucccccucac cgaagcaauc      720

caagcccucu ucgaacgagg ggaacgccgc cucaaccuag auguccaaug cgacagcugc      780

caagaacuag ccgucguccc cgucuucguc gaccccggcg aggaauccca ccgacccuuc      840

gucgucgucc aagcacgacu cggcgacucu cgccacagaa uacguaaacg aggacucgaa      900

ugcgacggcc gcaccaaccu cugcugcaga caacaauucu ucaucgacuu ccgccucauu      960

ggauggaacg acuggaucau agcacccacu ggauacuacg gcaacuacug cgaaggcucc     1020

ugccccgcau accucgcagg aguccccgga agcgcauccu cuuuccacac cgcaguagug     1080

aaccaauacc gcaugcgcgg ccucaacccc ggaaccguca acagcugcug cauccccacc     1140

aaacuuucca ccaugagcau gcucuacuuc gacgacgaau acaacaucgu aaaacgagac     1200

guccccaaca ugauaguaga agaaugcgga ugcgcauaag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  2289
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt9)

<400>  2289
gggagaaagc uuaccauggc acuaagggua cuccuccuca ccgcccucac acucugccac       60

ggauucaacc ucgacacuga aaacgcaaug acauuccaag aaaacgcgcg gggcuucgga      120

caaucagugg uccagcugca agguagccgc gucgucgugg gcgccccgca agagaucgua      180

gcagccaacc agcgcggcuc ucuauaucaa ugcgacuacu caacuggcag uugcgaaccc      240

aucagacuac aagucccagu cgaagcuguc aacaugagcc uuggacuauc gcuagccgca      300

acaaccucgc cuccucaacu ccucgccugc ggcccaaccg uccaccagac cugcuccgag      360

aauaccuacg ucaaaggccu cugcuuuuug uucggcucua accugcgcca acaaccgcaa      420

aaauucccgg aagcccugcg aggcugcccc caggaagacu cagacauagc uuuccuaauu      480

gacggguccg gcuccaucau accccacgac uuccgucgaa ugaaagaguu cguaucaacu      540

guaauggaac aacucaagaa aucuaaaacg cuguucucac ucaugcaaua cagcgaagag      600

uucaggaucc acuucaccuu caaagaguuc caaaacaacc caaacccacg cucgcucguc      660

aagccaauaa cccaacuccu cggcagaacc cauacagcua caggcauccg aaaagucguc      720

agagaacucu ucaacaucac caacggcgcc cggaaaaaug ccuucaaaau ccuuguaguc      780

aucaccgacg gugaaaaauu cggcgauccu cuuggauacg aagacguaau uccugaagcc      840

gacagagaag gagugauucg auacgucauc ggagugggcg acgcauuccg cagugaaaag      900

ucccgacaag aacugaacac caucgccucc aaaccucccc gagaccacgu uuuccaagua      960

aacaacuucg aagcacucaa gaccauccaa aaccaacugc gcgagaaaau auucgcaauc     1020

gaaggcacgc aaaccggguc caguucaucc uucgaacacg aaauguccca ggaaggauuu     1080

uccgcagcga ucacuuccaa cggacccuua cuauccacag ucggcucgua cgacugggcc     1140

ggcggcguau uccuauacac cagcaaagaa aaauccaccu ucaucaacau gacccggguc     1200

gacagcgaca ugaacgaugc cuaccucggg uaugcagccg caauuauacu aaggaaccgc     1260

guucaauccc ucguacuggg agcaccccgc uaccagcaca uaggccuagu ggcuauguuc     1320

cgucaaaaca caggcaugug ggaauccaau gccaacguua agggcacgca aauaggagcc     1380

uacuucggcg ccucucuaug cuccguagac guagacucca acggauccac agaccuagua     1440

cugaucggcg caccccacua cuacgaacaa accagaggcg gacaagucuc agugugucca     1500

cucccccgcg gucgagcacg auggcaaugu gaugccgucc uauacggcga acagggacaa     1560

ccguggggcc gcuuuggagc ugcccucacc guccucggcg auguaaacgg ugacaaacuc     1620

acugauguag ccauaggcgc ccccggagaa gaggauaaca gaggagccgu cuaccuauuc     1680

cacggcaccu caggaagcgg gaucagccca ucccacuccc aacgcauagc gggcucaaag     1740

cuaucgccuc gccugcagua cuuuggccaa agccucuccg gcggccaaga ccucaccaug     1800

gacggucuag uagaccucac aguaggagcc caaggacaug uacuccuccu ucgcucgcag     1860

cccguacuca gaguaaaggc caucauggaa uuuaauccaa gagaagucgc ccgaaacgua     1920

uucgaaugca acgaucaggu gguuaaaggu aaagaagccg gugagguacg cguaugucuc     1980

cacguacaaa aaucgacccg ggacagacuu cgcgaaggac aaauccaauc aguagucacc     2040

uacgaccucg cucuagacuc cggucguccc cauucacgag ccguguucaa cgaaaccaaa     2100

aacucuacaa gacgccaaac ucagguacuc ggcuugacac aaacuuguga gaccuuaaaa     2160

cuucagcugc caaacuguau cgaggacccc gucuccccaa ucguacugcg gcuuaacuuc     2220

ucucucgucg gcacaccccu uuccgcguuc gguaaccuga gacccguccu cgcagaagac     2280

gcccaacgac ucuucaccgc acucuucccc uuugagaaaa acugcggcaa cgacaacauc     2340

ugccaagaug acuuaagcau uacauucuca uuuaugagcc uagacugucu cguaguaggc     2400

ggaccccggg aauuuaacgu cacuguaacc gugcgcaacg acggugaaga cuccuacagg     2460

acgcaaguca cauucuucuu cccccucgac uuaagcuacc guaaagucag cacccuucag     2520

aaccagcguu cucaacgauc cuggaggcuu gcgugcgaau cagcuagcuc aaccgagguc     2580

uccggcgcgc ucaaauccac cucaugcucc aucaaccacc ccaucuuccc cgaaaacagc     2640

gaaguuaccu ucaacauaac cuucgacgua gacuccaagg caucacuagg aaacaaacuc     2700

cuccucaagg ccaacguaac cuccgagaau aacaugccac gcacgaauaa aacagaguuc     2760

caauuggaac uccccguaaa auacgcggua uacauggucg ucacuucuca cggaguaucu     2820

accaaauacc uaaacuuuac agccuccgaa aacacaagcc gaguaaugca gcaucaauac     2880

caagugucaa accugggaca aagaucgcua ccuaucucac ucgucuuccu gguaccgguc     2940

aggcuuaacc aaacggucau augggaccgc ccccaaguaa ccuuuucaga aaaccucucc     3000

agcacaugcc acaccaaaga aaggcuccca ucacauagcg acuuccuagc agagcuccgc     3060

aaggcgcccg ucguuaacug cuccauagca gugugccaac gcauccagug cgacauacca     3120

uucuuuggca uccaggagga guucaacgca acccucaagg gaaaccucuc uuucgacugg     3180

uacauaaaaa cuucccacaa ucaccuccua aucgucucca ccgcagaaau ccucuucaac     3240

gacagcguau ucacccuacu accaggccag ggagcguucg uccggagcca aaccgaaacc     3300

aaaguggaac cauuugaagu acccaacccc uuaccccuaa ucgucggguc cucagucggc     3360

ggccuacuac uucucgcuuu aaucaccgcc gcccucuaca aacuaggcuu uuucaaaaga     3420

caauacaaag acaugauguc cgaaggaggc ccacccgggg ccgaaccgca auaaggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  2290
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt9)

<400>  2290
gggagaaagc uuaccauguu cagccucaaa acgcuccccu uccuccuacu ccuccacguc       60

caaauaucua aagccuuucc cgucuccucu aaagaaaaga acacaaaaac aguacaagac      120

uaccuggaaa aauucuacca acucccaucc aaccaauacc agucaacccg caaaaacggc      180

accaacguaa ucgucgaaaa acucaaagaa augcaacgcu ucuucggacu caacgucacu      240

gguaaaccaa acgaagaaac ccucgacaug augaaaaagc cgagaugcgg cguaccagac      300

uccggcggcu uuaugcucac ccccggaaac ccgaaauggg aacgcaccaa ccucaccuac      360

cgcauacgaa acuacacacc ccaacucucu gaagccgaag ucgaacgugc caucaaagac      420

gccuucgaac ucuggucagu agccucccca cucauuuuca cacgaaucuc ccaaggugaa      480

gccgacauca acaucgccuu cuaccaacga gaccacggcg acaauucccc cuuugacggc      540

ccaaacggaa uacuagccca cgccuuccaa cccggucaag gcaucggcgg cgacgcccac      600

uucgacgcag aagaaaccug gaccaauacc uccgcaaacu acaaccucuu ccucgucgca      660

gcccacgaau uuggacacuc acucggccuc gcacacucua gcgaccccgg cgcccucaug      720

uaccccaacu acgccuuccg agaaaccucc aacuacucac ucccgcaaga cgacaucgau      780

ggaauccaag ccaucuacgg ccucuccucc aacccaaucc aacccacugg ccccucaacc      840

cccaaacccu gugacccauc ccucacauuc gacgccauua ccacccuccg cggggaaauc      900

cucuucuuca aagaucgcua cuucuggcgc cgacaccccc aacuacaacg cgucgaaaug      960

aauuucaucu cccucuucug gcccucccuc ccuaccggca uucaagccgc cuacgaagac     1020

uucgaucgcg accuuauuuu ucucuuuaaa ggcaaccaau acugggcccu cucgggcuac     1080

gacauccuac aaggauaccc caaagacauc uccaacuacg gauuccccuc uuccguccaa     1140

gcuauagacg ccgccgucuu cuaccgaucc aagacauacu ucuucgucaa ugaccaauuc     1200

uggcgauacg acaaccaacg acaguucaug gaacccgggu accccaaauc cauuuccgga     1260

gccuucccag gcaucgaauc caaagucgac gccgucuucc agcaagaaca cuucuuccac     1320

gucuucucag gcccccgcua cuacgccuuc gaccuaaucg cccaacgcgu cacccgcguc     1380

gcccgaggca acaaauggcu caacugcaga uacggauaag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2291
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt9)

<400>  2291
gggagaaagc uuaccaugag ccuguggcaa ccccucgucc ucguccuucu uguccucggu       60

ugcuguuucg ccgcaccccg ccaacgacag uccacccucg uccucuuccc cggagaccuc      120

cgcacaaacc uaacugaccg ccagcucgcc gaagaauauc uuuaccgcua cggcuacacc      180

cgcgucgcag aaaugagagg cgaauccaaa ucucuggggc ccgcccuccu ccuccuccaa      240

aaacagcucu cccuccccga gaccggagaa cuugacuccg ccacccucaa agcaaugcga      300

acaccacgcu gcggcguccc agaccucggc cgcuuccaaa cguucgaagg cgaccuaaaa      360

uggcaucauc acaacauuac cuacuggauc caaaacuacu ccgaagaccu cccccgcgcc      420

guaauagacg acgccuucgc cagagccuuc gcgcucuggu ccgccgucac cccacuaaca      480

uucacccgcg ucuacucacg cgacgccgac auagugauuc aauucggugu cgcugaacac      540

ggggacggcu accccuucga cggaaaagac ggccuacugg cccacgcauu cccacccgga      600

cccggaaucc aaggugacgc ccacuuugac gacgacgagc uuuggucccu aggaaagggc      660

gucguagucc caacacgcuu cggaaacgca gacggcgccg cuugccacuu ccccuucaua      720

uucgaaggaa gguccuacuc agcaugcacc accgacggcc gaucagacgg ccucccgugg      780

ugcucgacca cagcgaacua cgacacagau gaccgcuucg gcuucugccc cucagaacga      840

cuauacaccc aggacggcaa cgccgacgga aaacccugcc aauucccauu cauauuccag      900

ggucagagcu acuccgccug uacgacggac ggcagaagcg auggcuaccg cuggugcgca      960

accacagcga acuacgaccg agacaaacuu uucgguuucu guccaacccg cgcagacucc     1020

accguaaugg gcggcaacag cgccggagaa cuaugcgucu ucccauucac cuuccucgga     1080

aaagaauacu ccacuuguac cucggaaggc agaggcgacg gaagacucug gugugcuaca     1140

accucaaacu ucgacuccga caagaaaugg ggcuucugcc ccgaucaagg cuacagucua     1200

uuccucgucg cagcccacga guucggacac gcccucgggc ucgaccacuc cuccguaccc     1260

gaagcgcuaa uguacccaau guacagguuu accgaaggac caccccuaca caaagacgac     1320

gucaacggaa uccgccaccu uuacggcccc cgccccgaac ccgaaccucg uccacccacc     1380

acaacaacac cccaacccac cgcaccgcca accguauguc ccacggggcc cccuaccguc     1440

cacccgagcg aaagacccac agcaggcccu accgguccac ccucagcagg acccacagga     1500

cccccuacug ccggccccuc uacagccacu acuguccccc uaagcccagu ugacgacgca     1560

ugcaacguaa acauauuuga cgcaaucgcc gaaaucggca accaacuuua ccuauucaaa     1620

gacgguaaau acuggcgauu cuccgaagga cgcggaaguc gcccccaggg cccauuccua     1680

aucgcagaca aauggccagc ccuaccgaga aaacuagauu cagucuucga agaaagacua     1740

agcaagaaac ucuucuucuu uucuggccga caaguauggg uauacacagg agccagcgua     1800

cuaggcccca gaagacucga caaacuaggc cuaggagcag acguugcaca aguaaccgga     1860

gcucuccguu ccggcagagg caaaaugcua uuguucucug gccgcagacu uuggcgcuuc     1920

gacgucaaag cucaaauggu agacccccga uccgcauccg aggucgaccg cauguucccc     1980

ggcguccccu uagacacaca cgacguuuuc caguaccgag agaaagccua cuucugccaa     2040

gaccgcuucu acuggagagu aagcagcagg uccgaacuca accaaguaga ccaagucgga     2100

uacguaacau acgacauccu ccaaugccca gaagacugag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  2292
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt9)

<400>  2292
gggagaaagc uuaccaugca ccccggaguc cucgccgcau uccuauuccu cuccuggacc       60

cacugccgag cccuaccccu cccauccggc ggagacgaag augaccucuc cgaagaagac      120

cuccaauucg cagaacgcua ccuucgcucc uacuaccacc caaccaaucu cgcaggcauc      180

cuaaaagaaa acgccgcauc cucaaugacc gaacgccucc gagaaaugca auccuucuuc      240

ggccucgaag ucaccggcaa acucgacgac aacacccucg acguaaugaa aaaaccuaga      300

ugcggagucc cagacgucgg agaauacaac guauuccccc guacccugaa auggucaaaa      360

augaaccuca cguacaggau cguaaacuac acccccgaca ugacccauag cgaagucgaa      420

aaagccuuca aaaaagccuu caaagucugg uccgacguca cuccacuaaa cuucacccgu      480

cuccacgacg gcauagccga caucaugaua uccuucggaa ucaaagagca cggcgacuuc      540

uaccccuucg acggacccag cggucuccuc gcacacgccu uccccccggg ccccaacuac      600

ggcggagacg cccacuucga ugacgacgag accuggacau ccuccucaaa gggcuacaac      660

cucuuccucg ucgccgccca cgaauucggg cacucacuug gacucgacca uuccaaagac      720

cccggagccc ucauguuccc aaucuacaca uacaccggca aaagucacuu caugcucccc      780

gacgacgacg uccaaggaau ucaaagccuc uacggccccg gcgaugaaga ccccaacccc      840

aaacauccca aaacacccga caagugcgac ccuucccuca gccucgacgc aaucaccuca      900

cucagaggcg aaaccaugau auucaaagac cgauucuucu ggcgacucca cccgcaacaa      960

guagacgccg aacuauuccu aaccaaaucc uucuggccag aacuaccuaa ccgaaucgac     1020

gccgccuacg aacaccccag ccacgaccuc aucuucaucu uccgcggcag aaaauucugg     1080

gcccucaacg gcuacgacau ccucgaaggc uaccccaaaa aaauaucuga acucggccuc     1140

ccaaaagaag ucaaaaaaau auccgccgcc guccacuucg aagacaccgg caaaacccua     1200

cucuuuagcg gcaaccaagu cuggcgauac gacgacacga accacaucau ggacaaagac     1260

uacccucgcc ucaucgaaga agacuuccca ggaaucggcg auaaaguaga cgcgguuuac     1320

gaaaaaaacg gcuacaucua cuucuucaac ggcccaauac aauucgaaua cuccauaugg     1380

uccaaccgaa uagucagagu gaugccagca aauucaaucc ucuggugcua aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2293
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt9)

<400>  2293
gggagaaagc uuaccaugga aacccccaac acaaccgaag acuacgacac caccacggag       60

uucgacuacg gcgacgccac ccccugccaa aagguaaacg aacgagccuu cggcgcacaa      120

cuucucccac cccuguacuc ccuaguguuc guaauaggcc ucgucggcaa uauccuaguc      180

guauuagucc ucguccaaua caaacgccuc aagaacauga ccucuauaua ccuacucaac      240

cuagcaaucu ccgaccuccu uuuccuguuc acccuccccu ucuggaucga cuauaaacuc      300

aaagacgauu gggucuucgg agacgccaug ugcaaaaucc ucuccggcuu cuauuauacc      360

ggucucuacu ccgaaaucuu cuucauaauc cuccucacca ucgacagaua ucucgccaua      420

guccacgccg ucuuugcacu ccgcgcccgc accgucaccu ucggugucau caccuccauc      480

auaaucuggg ccuuagccau ccucgccucc augcccggac ucuacuuuuc caaaacccaa      540

ugggaguuca cccaccauac cugcucccuc cacuuccccc acgaaucccu acgcgaaugg      600

aaacucuucc aagcacuaaa acuaaaccuc uuuggccucg uccuuccccu ccuagucaug      660

aucaucugcu acacaggcau caucaaaauc cuacuucguc gcccuaauga aaagaaaucc      720

aaagccgucc gacucaucuu cgucaucaug auaaucuuuu uccucuucug gacacccuau      780

aaucucacca uccucaucuc ugucuuccaa gacuuccucu ucacacacga augcgaacaa      840

ucccgccacc uagaccucgc cguccaaguc accgaaguca ucgcauacac ccacugcugc      900

gucaaccccg ucauauacgc auucgucggc gaacgcuucc gcaaguaccu ccgccaacuc      960

uuccaccgac gcgucgcagu ccaucucguc aaaugguuac ccuuucucuc ugucgaccgc     1020

cucgaacgcg uauccucaac aucacccucc accggcgaac augaacuuuc agccggcuuc     1080

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  2294
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt9)

<400>  2294
gggagaaagc uuaccaugcg aacccucgcc ugccuccucc uccucggcug cggcuaccuc       60

gcccacguac ucgccgaaga agcagaaauc ccccgcgaag ucaucgaacg ccucgcacgc      120

ucccaaaucc acuccauccg ugaccuccaa cgacuccugg aaaucgacuc cgucggaucc      180

gaagacuccc uagacaccuc ccuaagagcc cacggcguac acgccacaaa acacgucccc      240

gaaaaacgac cccuccccau ccgcagaaaa cgauccauag aagaagccgu ccccgccgua      300

ugcaaaacac gcacagucau cuacgaaaua ccccgcuccc aagucgaccc aaccuccgcc      360

aacuuccuaa ucuggccccc cugcgucgaa gucaaacgcu gcaccggcug cugcaacacc      420

uccucaguca aaugccaacc cagccgcguc caccaccgca gcgucaaagu cgcaaaaguc      480

gaauacguac gcaaaaaacc caaacucaaa gaaguccaag ucagacucga agaacaccua      540

gaaugcgcau gcgccaccac cagccuaaac ccagacuacc gcgaagaaga caccggccga      600

ccccgcgaau ccggcaaaaa acgcaaacgc aaaagacuaa aacccaccua aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  2295
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt9)

<400>  2295
gggagaaagc uuaccaugaa ccgcugcugg gcccuauucc uaagccuaug cugcuaccuc       60

cgccuagucu cggccgaggg cgaccccauc cccgaagaac ucuacgaaau gcucagcgau      120

cacucaaucc gcuccuucga cgaccuccaa cgccuccucc acggcgaccc cggcgaagaa      180

gacggagccg aacuagaccu caacaugaca cgcucacacu ccggagggga acucgaaucc      240

cucgcacgcg gccgccgcag ccuaggcuca cuaacaaucg ccgaaccagc aaugaucgcc      300

gaaugcaaaa caagaacaga agucuucgaa aucucacgcc gccuaaucga ccgcaccaac      360

gccaacuucc uagucuggcc acccugcguc gaaguccaaa gaugcuccgg augcugcaac      420

aacagaaacg uccaaugccg ccccacccaa guccaacucc gaccaguaca aguaagaaaa      480

auagaaaucg uccgcaaaaa acccaucuuc aaaaaagcaa ccguaacccu cgaagaccac      540

cucgcaugca aaugcgaaac cgucgccgca gcccgccccg ucacccgcag ccccggcgga      600

agccaagaac aacgagcaaa aacaccccaa accagaguca ccauccgaac aguccgcgua      660

cgcagacccc ccaaaggaaa acaccgcaaa uucaaacaca cacacgacaa aaccgcccua      720

aaagaaaccc uaggcgccua aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  2296
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt9)

<400>  2296
gggagaaagc uuaccauguc ccucuucggc cuacuccucc uaacaucugc acucgccggc       60

caacgccaag gcacccaagc cgaauccaac cucagcucua aauuccaauu cuccucaaac      120

aaagaacaaa acggcgucca agacccccaa cacgaacgca uaaucacagu cucaaccaac      180

ggcuccaucc auucaccccg uuucccccac accuaccccc gcaacaccgu ccuaguaugg      240

cgccuaguag caguagagga aaacgucugg auccaacuca ccuucgacga acgcuuugga      300

cucgaagauc cagaagacga uaucugcaaa uacgacuucg ucgaaguaga agaaccuucc      360

gacggcacaa uccuaggccg auggugcggc uccggcaccg ucccaggcaa acaaauaucc      420

aaaggcaacc aaauccgcau ccgcuucguc uccgacgaau acuuccccuc cgaacccggc      480

uucugcaucc acuacaacau cgucaugccc caauucaccg aagccgucuc ccccuccguc      540

cucccacccu ccgcacuccc ccuagaccug cucaacaacg ccaucaccgc cuucucaacc      600

cucgaggacc ucauacgcua ccuagagccc gaacgcuggc aacucgaccu cgaagaccuc      660

uaccgcccaa cauggcaacu ccucggcaaa gccuucgucu ucggccgcaa aucccgcgua      720

gucgaccuaa accuacuaac cgaagaagua cgccucuaca gcugcacacc acgcaacuuc      780

ucagucucca uccgcgaaga acucaaacgc accgacacca ucuucuggcc aggcugccuc      840

cuaguaaaac gcugcggcgg gaacugcgcc ugcugccucc acaacugcaa cgaaugccaa      900

ugcgucccau ccaaagucac caagaaauac cacgaagugc uacaacuaag accaaaaacc      960

ggcguccgcg gacuccacaa aucucucacc gacguagccc uagaacacca cgaagaaugc     1020

gacugcgucu gccgcggcuc caccggcggc uaaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  2297
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt9)

<400>  2297
gggagaaagc uuaccaugca ccgccucaua uuugucuaca cacugauaug cgccaacuuc       60

uguucaugcc gcgacaccuc cgccaccccc caaucugccu ccauaaaagc ccucagaaac      120

gccaaccuac gacgcgacga ccucuaccga cgcgacgaaa caauacaagu caaaggcaac      180

ggcuacguac aauccccacg cuuccccaac uccuaccccc gcaaccuccu ccucaccugg      240

cggcuacacu cccaagaaaa cacccgcaua cagcuuguau ucgacaacca auucggccua      300

gaagaagccg agaacgacau cugccgauac gacuucgucg aagucgaaga caucagcgaa      360

accuccacca ucaucagagg aagauggugc ggccacaaag aagucccccc ucgaaucaaa      420

ucccgcacaa accagauaaa aauaacauuc aaauccgacg acuacuucgu cgccaaaccc      480

ggcuucaaaa ucuacuacuc ccuccucgaa gauuuccaac ccgccgccgc cuccgaaaca      540

aacugggaau ccgucaccuc cuccauaucc ggugucucau acaacucccc aagcgucaca      600

gacccaaccc ucauugcaga cgcacuagac aaaaaaaucg ccgaauucga caccgucgag      660

gaccuccuaa aauacuucaa ccccgaaucc uggcaagaag accucgaaaa cauguaccuc      720

gacacacccc gcuacagagg ccgcuccuac cacgaccgca aauccaaggu cgaccucgac      780

cgccucaacg acgacgccaa acgcuacagc ugcacacccc gcaauuacag ugucaacauc      840

agagaggaac uaaaacuagc caacguaguc uucuucccac gcugccuacu aguacagcga      900

ugcggcggca acugcggcug cggcaccgug aacuggcggu ccugcaccug uaacuccggc      960

aaaacaguaa aaaaauauca cgaaguccua caguuugaac ccggacacau caaacgccgu     1020

ggccgcgcca aaacuauggc ccucguugac auccaacucg accaccacga acgcugcgac     1080

ugcauaugcu cuucccgccc accccgauaa ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  2298
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt9)

<400>  2298
gggagaaagc uuaccauggu cacccauuca aaauuccccg ccgccggcau gucccgcccc       60

cucgacaccu cccuccgccu caaaacauuc uccuccaaau ccgaauacca acucgucguc      120

aacgccgucc gcaaacucca agaauccggc uucuacuggu cugccgucac cggaggcgaa      180

gccaaccucc uacuaucagc cgaaccagcu ggcaccuucc uaauccguga cuccuccgac      240

caacgccacu ucuucacccu cucagucaaa acccaauccg gcaccaaaaa ccuccgcauc      300

caaugcgaag gcggauccuu cucccuacaa uccgaccccc gcucaacuca accagucccc      360

cgauucgacu gcguccucaa acucguccac cacuacaugc ccccacccgg agcccccucc      420

uuccccuccc cacccaccga acccuccucc gaaguccccg aacaacccuc cgcccaaccc      480

cuccccggau caccaccccg ccgcgccuac uacaucuacu ccggcggcga gaaaaucccc      540

cuaguccucu cccgcccacu cucauccaau guugccaccc uacaacaccu cugccguaaa      600

accguaaacg gacaccuaga cuccuacgaa aaaguuaccc aacuacccgg ccccauccgc      660

gaauuucucg accaauacga ugcaccccuc uaaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  2299
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt9)

<400>  2299
gggagaaagc uuaccauggu ccccuccgcc ggccaacuag cccucuucgc ccuaggcauc       60

guccucgcag ccugucaagc acucgaaaac uccaccuccc cccucucagc cgacccaccc      120

guagccgcag ccguagucuc ccacuucaac gacugccccg acucccacac ccaauucugc      180

uuccacggaa ccugccgauu ccucguccaa gaagacaaac ccgccugcgu augccacucc      240

ggcuacgucg gcgcccgcug cgaacacgcc gaccuccuag ccguaguagc cgccucacaa      300

aaaaaacaag ccauaaccgc acucguaguc gucuccaucg ucgcccucgc cguccuuaua      360

auaaccugcg uccucaucca cugcugccaa guacgcaaac acugcgaaug gugccgcgcc      420

cucaucugca gacacgaaaa acccuccgca cuacucaaag gccgcaccgc cugcugccau      480

uccgaaaccg uaguauaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  2300
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt9)

<400>  2300
gggagaaagc uuaccaugcc accauccggc cuacgucucc ucccucuccu ccugccacuc       60

cucuggcuau uaguccuaac accaggccgc ccagccgccg gccucucaac cugcaaaacu      120

aucgacaugg aacuugucaa acgcaaacga auagaagcca uccgcggcca aauccuaucc      180

aaacuccgcc ucgccucccc acccucacaa ggcgaaguac cacccggacc ccuacccgaa      240

gccguccuug cacucuauaa cuccacccgc gaccgaguug cuggagaauc agccgaaccc      300

gaaccagagc cagaagccga cuacuacgcc aaagaaguca cccgcguacu cauggucgaa      360

acacacaacg agauauacga uaaauucaag caauccaccc acuccauaua cauguucuuc      420

aacaccucag aacuacgaga agccgucccc gaacccgucc uacuaucacg agccgaacuu      480

cgucuccucc gacucaaacu caaggucgaa caacacgucg aacucuacca aaaauauuca      540

aacaacucau ggcgcuaccu aucaaaccgc cuacuagcac caucagacuc acccgaaugg      600

cuaucauucg acgucaccgg agucguccgc caauggcuau cacgaggagg cgaaaucgaa      660

ggcuucagac ucucagccca cugcuccugc gacucccgag acaacacccu ccaagucgac      720

aucaacggcu ucaccaccgg ccgacgcgga gaccucgcca caauacacgg aaugaaccga      780

cccuuccuac uccucauggc aacaccacuc gaacgcgccc aacaccucca aucuucccgc      840

caccgccgag cccuggacac caacuacugc uucuccucca cugagaaaaa uugcugcgug      900

agacaacucu acaucgacuu ccgcaaagac cucggcugga aauggaucca cgaaccaaaa      960

ggcuaccacg caaacuucug ccucggcccc ugcccauaca uauggucccu agacacccaa     1020

uacuccaaag uucuagcccu auacaaccaa cacaaccccg gcgccuccgc ggcucccugc     1080

ugcguucccc aagcccucga accccuccca auagucuacu acgucggccg caaaccaaaa     1140

gucgaacaac ucuccaacau gaucguccga uccugcaaau gcuccuaagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  2301
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt9)

<400>  2301
gggagaaagc uuaccaugca cuacugcgua cucucagccu uccucauccu ccaccucguc       60

accgucgcac uaucacuauc uaccugcagc acacucgaua uggaccaauu caugcgcaaa      120

cgcauagaag cuauccgugg ccaaauccua uccaaacuca agcucaccag cccacccgaa      180

gacuauccug aacccgaaga agucccaccc gaaguaaucu ccaucuacaa cuccacacgc      240

gaccuccuac aagaaaaagc cucccgacgc gcagccgccu gcgaacgaga gcgcuccgac      300

gaagaauacu acgccaaaga aguauacaag auagacaugc cacccuucuu cccuuccgaa      360

aacgccauac ccccaaccuu cuaccgccca uacuuccgca ucguccgcuu cgacgucucu      420

gcuauggaga aaaaugcauc caaccucguc aaagccgagu uccgcguauu ccgccuacaa      480

aaccccaaag cgcgcguccc ugaacaacgc aucgaacucu accagauccu caaauccaaa      540

gaucuuaccu cgcccacaca acgcuacauc gacuccaaag ucguaaagac ccgcgccgaa      600

ggagaauggc ucuccuucga cguaaccgac gccguccacg aauggcuaca ccacaaagac      660

cgcaaccucg gcuucaaaau cucccuacac ugccccugcu gcaccuucgu ccccuccaac      720

aauuacauca uccccaauaa auccgaagaa cucgaagcca gauucgccgg caucgacggc      780

accucaaccu acacauccgg cgaccagaaa accaucaaau caacccgcaa gaaaaacucc      840

ggcaaaaccc cacaucuccu ccucaugcuu cucccuucau accgucucga aucucaacaa      900

accaaccgac gcaagaaacg cgcccucgac gccgccuacu guuuccgcaa cguccaagac      960

aacugcugcc uacgaccccu cuacauagac uucaaacgcg accucggcug gaaauggauc     1020

cacgaaccca aaggcuacaa cgcuaacuuc ugcgcgggcg ccugccccua ccuauggucc     1080

uccgacaccc aacacucacg cguccucucc cucuacaaca ccaucaaucc ugaagccucc     1140

gccucacccu gcugcgucuc ccaagaccuc gaaccacuca ccauacuaua cuacaucggc     1200

aaaacgccua aaauagaaca acuaucuaac augaucguca aauccuguaa augcagcuaa     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  2302
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt9)

<400>  2302
gggagaaagc uuaccaugaa aaugcaccuc caacgcgccc uagucguacu cgcacuacuc       60

aacuuugcca ccguaucacu uucacucucc acaugcacca cacucgacuu uggccacauc      120

aaaaagaaac gagucgaagc uauacgaggc caaauccuau caaaacuacg ccucacaucc      180

ccacccgaac ccacaguaau gacccacguc cccuaccaag uacucgcccu auacaacucc      240

acccgcgaac uccuagaaga aaugcacgga gaaagagaag aaggaugcac ccaggaaaac      300

accgaaucag aauacuacgc caaagaaaua cacaaauucg acaugaucca aggccucgcc      360

gaacacaacg aauuagccgu cugccccaaa gguaucacua gcaaaguauu ccgauucaac      420

guuuccucgg ucgagaaaaa ccgcaccaac cuauuccgag ccgaguuccg uguccuccgc      480

guccccaacc caagcucaaa acgcaacgaa caacgcaucg aacuuuucca aauacuaaga      540

cccgacgaac acaucgccaa acaacgcuac auaggcggca aaaaccuccc aacccgcggc      600

accgcagaau ggcucucuuu cgacgucacc gacaccguac gugaauggcu acucagacgc      660

gaauccaacc uaggucuaga aaucucaaua cacugccccu gccacaccuu ccaaccaaac      720

ggagacaucc ucgaaaacau ccacgaaguc auggaaauca aauucaaagg agucgacaau      780

gaagacgacc acggacgagg cgaccucgga cgacucaaaa agcaaaaaga ccaccacaac      840

ccccaccuca uccuaaugau gaucccaccc caccgccucg acaaccccgg acaaggcggc      900

caacgcaaga aacgcgcccu cgacaccaac uacugcuucc gcaaccuaga agaaaacugc      960

ugcguacgcc cccucuacau cgacuuccga caagaccuag gcuggaaaug gguccacgaa     1020

cccaaaggau acuacgcaaa uuucugcagc ggaccaugcc cauaccuacg guccgccgac     1080

acaacccacu ccacaguccu aggacuuuau aacacccuaa acccagaagc cuccgccucc     1140

cccugcugug ucccccaaga ccuugaaccu cucaccaucc uuuacuacgu cggcagaacc     1200

cccaaagucg aacaacuauc caacaugguc gucaaauccu gcaaaugcuc cuaaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2303
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt9)

<400>  2303
gggagaaagc uuaccauggc acccguugca gucugggcag cccuugccgu cggccucgaa       60

cucugggccg cugcccacgc ccuccccgcc caaguugccu ucacuccuua cgccccagaa      120

ccaggcucca caugccgacu ccgagaauac uaugaccaaa cagcccaaau gugcugcucc      180

aagugcuccc ccggccaaca cgccaaaguc uucuguacca aaaccucuga caccgucugc      240

gacuccugcg aagacuccac uuacacccaa cuauggaacu ggguacccga augccucucc      300

ugcggcucca gaugcucauc cgaccaaguc gaaacccaag caugcacacg cgaacaaaac      360

cgaaucugca caugcaggcc cggaugguac ugcgcacucu ccaaacaaga aggcugccgc      420

cucugcgcac cccuccgaaa augccgacca ggcuucggcg ucgcccgccc aggaacagaa      480

accuccgacg uagucugcaa acccugcgcc ccuggcacuu ucuccaacac aaccagcuca      540

accgacauau gccgcccaca ccaaaucugc aacgucguug caauacccgg caacgcaucc      600

auggacgccg ucugcaccuc cacaucgccc acccgaucca uggcacccgg cgccguccac      660

cucccccaac cugucucaac ccgaucacaa cacacacaac ccacccccga acccucaacc      720

gccccaucca ccucauuccu ucuacccaug ggccccuccc cacccgccga aggcuccacc      780

ggagacuucg cccucccagu cggccuaauc gucggcguca ccgcccuagg ccugcucauc      840

aucggagucg ucaacugcgu aaucaugacc caagucaaaa agaagccccu augucuccaa      900

agagaagcaa aaguaccuca ccuccccgcc gacaaagccc gcggcacaca aggccccgaa      960

caacaacacc uccuaaucac cgccccauca uccuccucau caagccucga aucaucagca     1020

ucagcucucg accgccgcgc cccaaccaga aaccaacccc aggccccagg cguagaagcc     1080

uccggagccg gagaagcccg agccucaaca ggcuccuccg acagcucucc cggcggccac     1140

ggcacacaag uaaacguaac cugcaucguc aauguaugcu cgucauccga ccauuccucc     1200

caaugcucaa gccaagccuc aucaaccaug ggcgacaccg acucaagccc aucugaaucc     1260

cccaaagacg aacaaguacc cuucaguaaa gaagaaugug ccuuccgauc ccaauuagaa     1320

acccccgaaa cacuccuagg auccaccgaa gaaaaacccu uaccccucgg ugucccagac     1380

gccggcauga aacccuccua aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  2304
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt9)

<400>  2304
gggagaaagc uuaccaugcc ggucaugcgc uuguucccgu gcuuucuaca gcucuuggca       60

gggcucgcac ucccagccgu gcccccgcaa cagugggcgu uaucggccgg gaacgggagc      120

ucggaagugg aagugguacc guuccaggaa gugugggggc gcucguacug ucgcgcgcua      180

gagcgccugg ucgaugucgu gagugaguac ccgagcgagg ucgagcacau guucucgccc      240

ucaugcguga gcuugcucag gugcacgggc uguugcgggg acgagaaccu gcacuguguc      300

ccggucgaga ccgcgaacgu gaccaugcaa uugcucaaga ucaggagcgg ggacaggccc      360

ucguacgugg aauugaccuu cagccagcac guacgcugug aaugucgccc acucagggaa      420

aagaugaagc cagaacgcag gcgaccgaaa gggcgcggga aaaggcgcag agaaaagcaa      480

aggcccacag acugucacuu augcggggac gcggucccga ggcgcugagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  2305
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt9)

<400>  2305
gggagaaagc uuaccaugac agaccgccag acagacaccg cgccaucgcc cucguaccac       60

cuccugcccg ggagaaggcg cacggucgac gccgcagccu cgcgaggaca agggcccgag      120

ccagcgccag gaggcggggu agagggcgug ggagcgcgag gggucgcgcu caaacucuuc      180

guccagcuuc ugggcugcag cagguucggg ggcgcaguag ugcgcgcagg cgaagccgag      240

cccucaggcg cggccaggag cgcaagcuca ggcagagagg aaccccagcc cgaggagggg      300

gaagaagaag aggaaaaaga agaagaaagg gguccacaau ggcgccuggg cgcgcgcaag      360

ccaggaaguu ggaccggaga agcagcagug ugcgcggacu cugcaccagc cgcgcgagcg      420

ccccaggcau uggccagagc aucaggcaga ggaggacgag uggcaagaag aggagccgag      480

gaaucaggac cgccccauag cccaagcagg cgagggagug cgagcagagc cggaccaggg      540

cgcgcaagcg agacaaugaa cuuccuccug agcuggguac acuggucgcu agcacuguug      600

cucuaccucc aucacgcaaa auggagccag gccgcgccaa uggccgaggg aggaggacaa      660

aaccaccacg agguagugaa auucauggac gucuaccaaa ggagcuauug ccaccccaua      720

gaaacgcuag uggacauauu ccaggaauau ccagacgaaa uagaguacau auucaaacca      780

agcugcgugc cgcucaugag gugcggcgga ugcuguaacg augaagggcu agagugcgua      840

cccacggaag agagcaacau caccaugcag aucaugagga uaaaaccgca ccagggccag      900

cacauaggag agaugucauu ccugcaacac aacaagugcg agugccggcc caagaaagac      960

cgagcaagac aggaaaagaa aucaguaagg ggaaagggca agggacagaa aagaaaaaga     1020

aagaagagua gguacaagag cuggagugua uacguagggg cgagaugcug ccugaugcca     1080

uggagccuac cgggaccgca cccaugcgga cccugcagcg aacgcaggaa acaccuguuc     1140

guccaggacc cacaaacaug caaguguuca ugcaagaaca cagacucgcg cuguaaagca     1200

cgccaacucg agcuuaacga aaggacaugc cgcugcgaca aacccaggag auaaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2306
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt9)

<400>  2306
gggagaaagc uuaccaugaa cuuccuacuc agcugggucc acuggucacu cgcccuccuc       60

cucuaccucc accacgccaa auggucccaa gccgccccca uggccgaagg cggcggccaa      120

aaccaccacg aaguaguaaa auucauggac guauaccaac gcagcuacug ccaccccauc      180

gaaacccuag uagacaucuu ccaagaauac cccgacgaaa ucgaauacau auucaaaccc      240

uccugcgucc cacucaugcg cugcggcggc ugcugcaacg acgaaggccu cgaaugcguc      300

cccacagaag aaagcaacau cacaaugcag auaaugcgaa ucaaacccca ccaaggccag      360

cacaucggcg aaaugucauu ccuccaacac aacaaaugcg aaugccgacc aaaaaaagac      420

cgcgcaagac aagaaaaaaa auccgucaga ggcaaaggca aaggccaaaa acgaaaacgc      480

aaaaaauccc gcuacaaaag cuggucaguc uacguaggcg cccgcugcug ccucaugcca      540

uggucccucc ccggccccca ccccugcggg cccugcagcg aacgccgcaa acaccucuuc      600

guccaagacc cacaaaccug caaaugcucc ugcaaaaaca ccgacucccg cugcaaagcc      660

cgccaacucg aacuaaacga acgcaccugc cgcugcgaca aaccccgaag auaaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  2307
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt9)

<400>  2307
gggagaaagc uuaccauguc cccccuccuc cgccgacucc uacuagccgc ccuccuacaa       60

cucgcccccg cacaagcccc cgucucccaa cccgacgccc ccggccacca acgcaaaguc      120

guauccugga uagacguaua cacccgcgcc accugccaac cacgagaagu cguaguccca      180

cucacagucg aacucauggg caccgucgca aaacaacucg uaccaucaug cguaaccguc      240

caacgaugcg gcggcugcug ccccgacgac ggccuagaau gcguccccac cggccaacac      300

caagucagaa ugcaaauccu caugauccgc uaccccuccu cccaacucgg cgaaauguca      360

cucgaagaac acucccaaug cgaaugccgc cccaaaaaaa aagacucagc cguaaaaccc      420

gaccgcgccg ccacaccaca ccaccgaccc caaccccgcu cagucccagg cugggacucc      480

gcccccggcg cacccucccc cgccgacauc acccacccca cccccgcacc cggccccucc      540

gcacacgccg ccccauccac caccuccgcc cucacccccg gccccgccgc cgccgccgcc      600

gacgccgccg ccagcuccgu cgcaaaaggc ggcgccuaag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  2308
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt9)

<400>  2308
gggagaaagc uuaccaugca ccuccucgga uucuucuccg ucgccugcuc ccuacucgcc       60

gccgcacucc uccccggccc acgcgaagca ccagcagccg ccgccgcauu cgaaucaggc      120

cucgaccuau ccgacgccga accagacgcc ggcgaagcca ccgccuaugc aagcaaagac      180

cucgaagaac aacuacgauc cguaucaucc guggacgaac uaaugaccgu ccucuaccca      240

gaauacugga aaauguacaa augccaacuc cgaaaaggcg gauggcaaca uaaccgcgaa      300

caagccaacc ucaacagccg aaccgaagaa acaaucaaau ucgccgccgc ccacuacaac      360

acggaaauac uaaaauccau cgacaacgaa uggagaaaaa cacaaugcau gccccgugaa      420

gucugcaucg acgucggcaa agaauuuggc gucgccacca acacauucuu caaaccaccc      480

ugcgucucag uauaccgaug cggcgggugc ugcaacuccg aaggccuaca augcaugaac      540

accuccaccu cauaccucuc aaaaacccuc uucgaaauaa caguuccacu cagccaaggc      600

cccaaacccg ucacgauauc cuucgcaaac cauacuucau gccgcugcau gucaaaacuu      660

gacguauacc gccaagucca cuccaucauc cgaagaucac uacccgccac ccuaccccaa      720

ugucaagccg ccaacaaaac cugccccacc aacuacaugu ggaacaacca cauuugccgc      780

ugccuagccc aagaagacuu cauguucuca ucggacgccg gcgacgacuc aaccgacggc      840

uuccacgaca uaugcggccc caacaaagaa cuagacgaag aaacaugcca augcgucugc      900

cgcgccggcc uccgacccgc auccugcgga ccccacaaag aacuggaccg caacucaugc      960

caaugcgucu gcaaaaacaa acucuucccc ucccaaugcg gcgcaaaccg cgaguucgac     1020

gaaaauaccu gccaaugcgu cugcaagcga accugcccac gcaaccaacc ccucaacccc     1080

ggaaagugcg ccugcgaaug caccgaaagc ccacaaaaau gccuucucaa aggaaagaaa     1140

uuccaccacc aaaccugcuc augcuaccgc cgccccugca ccaaccgcca aaaagccugc     1200

gaacccggcu ucucauacuc cgaagaagua ugccgcugcg uuccaagcua cuggaaacgc     1260

ccccaaaugu ccuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  2309
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt9)

<400>  2309
gggagaaagc uuaccaugua ccgagaaugg guagucguca acgucuucau gaugcucuac       60

guccaacugg uccaagguuc auccaacgaa cauggccccg ucaaacgcuc cucccagagc      120

acccucgagc gcuccgaaca acaaauccgc gcugccuccu cucuagaaga acuucuccga      180

aucacccacu cugaagacug gaaauuaugg cgaugccgcc uacgucucaa gagcuucacc      240

ucaauggacu cccgauccgc aucccaccgc ucuacacgau ucgccgccac cuucuacgac      300

aucgaaaccc ucaaagucau agacgaagaa uggcaacgca cccaaugcuc cccaagggaa      360

accugcgucg aaguagccuc cgaacucggc aaauccacca acacauucuu caaaccuccc      420

ugcgucaacg ucuuccgcug cggcggcugc ugcaacgaag aaucccucau cugcaugaac      480

acauccaccu ccuacauauc caaacaacua uucgaaauuu cugucccccu caccucgguc      540

cccgaacucg uccccgucaa aguagccaac cacaccggcu gcaaaugccu gcccaccgcc      600

ccacgacacc ccuauuccau cauccgacgc uccauacaga uucccgaaga agaccgaugc      660

ucccacucaa agaaacucug ccccauagac augcuauggg acucaaacaa augcaaaugc      720

guccuccaag aagaaaaccc acucgccggc acugaagacc acucgcaccu ccaagaaccc      780

gcccucugcg gaccccacau gauguucgac gaagaccgcu gcgaaugcgu cugcaaaacc      840

ccaugcccca aagaccucau ccaacacccc aaaaacugcu caugcuucga augcaaagaa      900

ucccucgaga ccugcugcca aaaacacaaa cucuuccacc ccgauaccug cuccugcgaa      960

gaccgcugcc ccuuccacac acgcccaugc gccuccggca aaaccgcaug cgcaaaacac     1020

ugccguuucc caaaagaaaa acgcgccgcc caaggccccc acucccgcaa aaaccccuaa     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  2310
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt11)

<400>  2310
gggagaaagc uuaccaugga cuccgacgaa accggcuucg aacacucagg ccucuggguc       60

uccguacuag ccggccuccu ccucggcgcc ugccaagccc accccauccc cgacuccuca      120

ccccuccuac aauucggcgg ccaaguccgc caacgcuacc uauacaccga cgacgcccaa      180

caaaccgaag cccaccucga aauccgcgaa gacggcaccg ucggcggcgc cgccgaccaa      240

ucccccgaau cccuacuaca acucaaagcc cucaaaccug gagucaucca aauacucggc      300

gucaaaaccu cccgcuuccu cugccaacgc cccgacggag cccucuacgg cucccuccac      360

uucgacccag aagccugcuc uuuccgagaa cuccucuuag aagacggcua caacgucuac      420

caaucugaag cccacggccu cccccuucac cuccccggaa acaaaucacc ccaccgcgac      480

cccgcacccc gcggcccagc cagauuccuc ccccuccccg gccucccacc agcccucccc      540

gaaccacccg gcauccucgc accccaacca cccgacgucg gcuccuccga cccccucuca      600

auggucggcc ccucccaagg ccgcuccccc ucauacgccu cauaaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  2311
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt11)

<400>  2311
gggagaaagc uuaccaugca cagcuuccca ccccuccucc uccuccuguu cuggggcguc       60

gucucacacu ccuuucccgc uacccucgaa acccaagaac aagacgucga ccucguacaa      120

aaguaccucg aaaaauacua caaccuuaaa aacgacggcc gucaagucga aaagcgccgc      180

aacucaggcc ccgucguuga aaaacucaaa caaaugcaag aauuuuucgg ccugaaaguc      240

acaggaaaac ccgacgccga aacccucaaa gucaugaaac aaccccgcug cggagucccc      300

gacguagccc aauucguccu aaccgaaggc aacccccgcu gggaacaaac ccaccucaca      360

uaccgcaucg aaaacuacac ccccgaccuu ccccgcgccg acgucgacca cgccauagaa      420

aaagcauucc aauuaugguc caacgucacc ccacucaccu ucacuaaggu cuccgaaggc      480

caagcagaca uaaugaucuc uuucguccgc ggcgaccacc gagacaacuc ccccuucgac      540

ggccccggag gcaaccuggc ccacgcauuc caaccaggcc ccggcaucgg aggagacgcc      600

cacuucgacg aagacgaacg cuggacaaac aauuucagag aauacaacuu acaucgcguc      660

gccgcccacg aacucggcca cagccucggc cucucacacu ccacagauau cggcgcccua      720

auguaccccu ccuacaccuu cuccggcgac guccaacuag cccaagacga cauagacggc      780

auccaagcca uauacggccg aucccaaaac cccguacagc ccaucggacc acaaacuccc      840

aaagccugcg acuccaaacu caccuucgac gccaucacca caauacgagg cgaagugaug      900

uucuucaaag acagauucua uaugagaacc aacccguucu accccgaagu cgaacuuaac      960

uucaucucag ucuucuggcc acaacuacca aacggccucg aagcagccua cgaauuugcc     1020

gaccgcgacg aaguccgauu cuucaagggc aacaaauacu gggccgucca aggccaaaac     1080

guccugcacg gcuacccaaa agacaucuau uccagcuucg gcuucccacg cacugucaaa     1140

cauaucgaug ccgcccucag cgaagaaaac acaggcaaaa cauacuucuu cgucgcuaac     1200

aaauacuggc gcuacgauga auacaaacgc uccauggacc caggcuaucc uaaaaugauc     1260

gcccacgacu uccccggcau cggccacaag gucgaugccg ucuucaugaa ggacggauuc     1320

uucuacuucu uccacggaac ccgccaauac aaguucgacc ccaaaacuaa gcgaauccuc     1380

acccuccaaa aagccaacuc cugguucaac ugccgcaaaa acuaaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  2312
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt11)

<400>  2312
gggagaaagc uuaccaugca uucauuccca ccacuacuac uccuccuauu cuggggaguc       60

gucucccauu ccuucguccu cacagaaggc aacccccgcu gggaacaaac ccaccucacc      120

uaccgcauag aaaacuacac cccagaccuc ccccgcgccg acgucgacca cgccaucgaa      180

aaagcguucc aacuaugguc uaacguaaca ccccucaccu ucaccaaagu cuccgaaggc      240

caagccgaca uaaugaucuc auucgucaga ggcgaccacc gcgacaacuc ucccuucgac      300

ggccccggag gcaaccucgc acacgccuuc caacccggcc ccggaaucgg cggcgacgcc      360

cacuucgacg aagacgaacg cuggaccaac aacuuccgag aauacaaccu ccaccgcguc      420

gccgcacacg aacucggcca cagccucggg cucucacacu ccaccgacau cggugcccuc      480

auguaccccu cauacacauu cucuggcgac guccaacucg cacaagacga caucgacggc      540

auccaagcca ucuacggccg aucccaaaac ccaguccaac ccauaggccc acagacaccc      600

aaagcaugcg acuccaaacu caccuucgac gccauaacca ccauccgcgg cgaaguaaug      660

uucuucaaag acagauucua caugcgcacc aaccccuucu acccagaagu ugaauuaaac      720

uucaucuccg ucuucuggcc acagcuccca aacggucucg aagccgcaua cgaauuugca      780

gaccgagacg aaguacgauu cuucaaaggc aacaaauauu gggccguaca ggggcaaaau      840

guccuccacg gcuacccuaa agacaucuac uccuccuucg gcuucccccg cacagucaaa      900

cacaucgacg ccgcccucuc cgaagaaaac accggcaaaa ccuacuucuu cgucgccaac      960

aaauacuggc gauacgacga auacaaacgc uccauggacc ccggauaccc caaaaugauc     1020

gcccacgacu uccccggcau cggccacaaa guagacgccg uuuucaugaa agacggauuc     1080

uucuacuucu uccacggaac aagacaguac aaauucgacc caaagaccaa acggauccuc     1140

acccuccaaa aagcaaacuc cugguucaau ugccgcaaaa auuaaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  2313
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt11)

<400>  2313
gggagaaagc uuaccaugaa gaagaacauc cugaagaucc ucauggacag cuacuccaag       60

gagagcaaga uccagaccgu gcgccggguc accuccguga gccugcuggc cguguaccuc      120

acgaugaaca ccuccagccu gguccuggcc aagcccaucg agaacaccaa cgacaccucc      180

aucaagaacg uggagaagcu ccgcaacgcg ccgaacgagg agaacagcaa gaagguggag      240

gacuccaaga acgacaaggu cgagcacgug aagaacaucg aggaggccaa gguggagcag      300

gucgcccccg aggucaagag caaguccacg cugcggagcg ccuccaucgc caacaccaac      360

agcgagaagu acgacuucga guaccugaac ggccucuccu acaccgagcu gaccaaccug      420

aucaagaaca ucaaguggaa ccagaucaac ggccucuuca acuacagcac ggggucccag      480

aaguucuucg gggacaagaa ccgcgugcag gcgaucauca acgcccugca ggagagcggc      540

cggaccuaca ccgccaacga caugaagggg aucgagaccu ucacggaggu gcugcgcgcc      600

ggcuucuacc ucggcuacua caacgacggg cuguccuacc ugaacgaccg gaacuuccag      660

gacaagugca uccccgcgau gaucgccauc cagaagaacc ccaacuucaa gcucggcacc      720

gccgugcagg acgaggugau caccagccug gggaagcuga ucggcaacgc cagcgccaac      780

gcggaggucg ugaacaacug cgugccgguc cucaagcagu uccgcgagaa ccugaaccag      840

uacgcccccg acuacgugaa ggggaccgcc gugaacgagc ugaucaaggg caucgaguuc      900

gacuucuccg gcgccgccua cgagaaggac gucaagacga ugcccuggua cgggaagauc      960

gaccccuuca ucaacgagcu caaggcgcug ggccuguacg ggaacaucac cagcgccacc     1020

gagugggccu ccgacguggg caucuacuac cucagcaagu ucggccugua cuccaccaac     1080

cggaacgaca ucgugcagag ccuggagaag gccgucgaca uguacaagua cgggaagauc     1140

gccuucgugg cgauggagcg caucacgugg gacuacgacg gcaucggguc caacggcaag     1200

aaggucgacc acgacaaguu ccucgacgac gccgagaagc acuaccugcc gaagaccuac     1260

accuucgaca acgggaccuu caucauccgg gccggcgaca aggugagcga ggagaagauc     1320

aagcgccugu acugggccuc ccgggagguc aagagccagu uccaccgcgu ggugggcaac     1380

gacaaggccc ucgagguggg gaacgcggac gacguccuga cgaugaagau cuucaacucc     1440

cccgaggagu acaaguucaa caccaacauc aacggcguga gcaccgacaa cgggggccug     1500

uacaucgagc cccgggggac cuucuacacg uacgagcgca cgccccagca guccaucuuc     1560

agccucgagg agcuguuccg gcacgaguac acccacuacc ugcaggcccg cuaccucgug     1620

gacggccugu ggggccaggg gccguucuac gagaagaacc ggcugaccug guucgacgag     1680

ggcaccgccg aguucuucgc cggguccacc cgcaccagcg gcguccuccc ccggaagucc     1740

auccuggggu accuggcgaa ggacaaggug gaccaccgcu acagccucaa gaagacccug     1800

aacuccggcu acgacgacag cgacuggaug uucuacaacu acggcuucgc cguggcccac     1860

uaccuguacg agaaggacau gcccacguuc aucaagauga acaaggccau ccucaacacc     1920

gacgucaaga gcuacgacga gaucaucaag aagcuguccg acgacgccaa caagaacacc     1980

gaguaccaga accacaucca ggagcuggcg gacaaguacc agggggccgg caucccccug     2040

gugagcgacg acuaccucaa ggaccacggg uacaagaagg ccuccgaggu guacagcgag     2100

aucuccaagg ccgccagccu gaccaacacc uccgucacgg cggagaaguc ccaguacuuc     2160

aacaccuuca cccugcgcgg caccuacacg ggcgagacca gcaaggggga guucaaggac     2220

ugggacgaga ugagcaagaa gcucgacggc acccuggagu cccuggccaa gaacagcugg     2280

uccggguaca agacccucac ggccuacuuc accaacuacc gggugaccag cgacaacaag     2340

gugcaguacg acgucguguu ccacggcgug cugaccgaca acgccgacau cuccaacaac     2400

aaggccccga ucgcgaaggu cacggggccc agcaccggcg ccgugggccg caacaucgag     2460

uucuccggga aggacagcaa ggacgaggac ggcaagaucg ugagcuacga cugggacuuc     2520

ggggacggcg ccaccucccg ggggaagaac agcguccacg ccuacaagaa ggcgggcacc     2580

uacaacguga cgcugaaggu gaccgacgac aagggcgcca ccgccaccga guccuucacg     2640

aucgagauca agaacgagga caccaccacc cccaucacga aggagaugga gcccaacgac     2700

gacaucaagg aggccaacgg gccgaucguc gagggcguga ccgugaaggg ggaccucaac     2760

ggcagcgacg acgccgacac cuucuacuuc gacgucaagg aggacgggga cgugaccauc     2820

gagcugcccu acuccggcag cuccaacuuc acguggcugg uguacaagga gggcgacgac     2880

cagaaccaca ucgcgagcgg gaucgacaag aacaacucca aggucggcac cuucaagagc     2940

accaaggggc gccacuacgu guucaucuac aagcacgacu ccgccagcaa caucuccuac     3000

agccucaaca ucaagggccu ggggaacgag aagcugaagg agaaggagaa caacgacucc     3060

agcgacaagg ccaccgugau ccccaacuuc aacacgacca ugcagggcuc ccuccugggc     3120

gacgacagcc gggacuacua cuccuucgag gucaaggagg agggggaggu gaacaucgag     3180

cuggacaaga aggacgaguu cggcgugacc uggacccucc accccgagag caacaucaac     3240

gaccgcauca cguacgggca ggucgacggc aacaagguga gcaacaaggu gaagcugcgg     3300

ccgggcaagu acuaccugcu cgucuacaag uacuccggga gcggcaacua cgagcugcgc     3360

gugaacaagu gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  2314
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt11)

<400>  2314
gggagaaagc uuaccaugaa gugggugaca uucaucagcc uccucuucuu auucuccagc       60

gccuacucca ucgccaacac caacagcgag aaguacgacu ucgaguaccu gaacggccuc      120

ucuuacacgg agcugaccaa ucugaucaag aacaucaagu ggaaccagau uaacggguua      180

uucaacuaca gcaccggcuc ccagaaguuc uucggggaca aaaaccgcgu ccaggcgauu      240

aucaacgccc ugcaggagag cggucggacc uacaccgcua acgacaugaa ggggaucgag      300

accuucaccg agguucugcg cgccggcuuc uaccucggcu acuacaacga cgggcugucc      360

uaccugaacg accggaacuu ccaggacaag ugcauccccg ccaugaucgc gauccagaag      420

aacccgaacu ucaagcucgg caccgccgug caggacgagg ucaucacgag ccuggggaag      480

cugaucggca acgccuccgc caacgcggag guggugaaca acugcguccc cgugcucaag      540

caauuccgcg aaaaccugaa ccaguacgcc cccgacuacg uaaaggggac cgccgucaac      600

gagcugauca agggcaucga guucgacuuu agcggcgccg ccuacgagaa agacgugaag      660

accaugcccu gguacgggaa gaucgacccg uucaucaacg agcucaaggc gcugggccug      720

uacgggaaca ucaccuccgc cacggagugg gccagcgacg ugggcaucua cuaccucucc      780

aaguucggcc uguacucgac caaccggaau gacaucguac agucccugga gaaggccgug      840

gacauguaca aguacgggaa gaucgccuuc guggcgaugg agcgcaucac cugggacuac      900

gacgguaucg ggagcaacgg caagaagguc gaccacgaca aauuccucga cgacgccgag      960

aagcacuacc ugcccaagac cuacacguuc gacaacggca ccuucaucau ccgggccggu     1020

gacaaggugu ccgaggagaa gaucaagcgc cuguacuggg ccagccgaga ggucaagagc     1080

caguuccacc gcgugguggg caacgacaag gcccucgagg uggggaacgc ggacgacguc     1140

cugaccauga agaucuucaa cuccccugag gaguacaagu ucaacaccaa caucaacggc     1200

guguccacgg auaacggggg ccuguacauc gagccccggg ggaccuucua caccuaugag     1260

cgcaccccgc agcaguccau cuucagccuc gaggagcugu uucggcacga guacacgcac     1320

uaccugcagg cccgcuacuu aguggacggc cuguggggcc aggggcccuu cuacgagaag     1380

aaccggcuga ccugguucga cgagggcacc gccgaguucu ucgccgguuc cacccgcacg     1440

agcggcgucc ucccccgaaa guccauccug ggguaccugg ccaaggacaa gguggaccac     1500

cgcuacagcc ucaagaagac ccugaacucc ggcuacgacg acucggacug gauguucuac     1560

aacuacggcu ucgcggucgc ccacuaccug uacgagaagg acaugcccac cuucaucaag     1620

augaacaagg ccauccucaa caccgacgug aaguccuacg acgagaucau caagaagcug     1680

agcgacgacg ccaacaagaa cacggaguac cagaaccaca uccaggagcu ggcggacaaa     1740

uaccagggug ccggcauccc ucucgugucc gacgacuacc ugaaggacca cggguacaag     1800

aaggccagcg aggucuacuc cgagauuagc aaggccgccu cccugaccaa caccagcgug     1860

accgcggaga agucccagua cuucaacacg uucacccucc ggggcaccua caccggcgaa     1920

accagcaagg gggaguucaa ggacugggac gagaugagca agaagcugga cggcacgcug     1980

gaaucccugg ccaagaacag cugguccggg uacaagaccc ucaccgccua uuuuaccaac     2040

uaccgcguga cgagcgacaa caagguccag uacgacgugg uguuccacgg cguccugacc     2100

gacaacgccg acaucuccaa caacaaggcc cccaucgcga aggugaccgg gcccagcacc     2160

ggcgccgugg gccggaacau cgaguucucc gggaaggacu cuaaggacga ggacggcaag     2220

auagucuccu acgacuggga cuucggggac ggcgccacgu cccgcgggaa gaacuccguc     2280

cacgccuaca agaaggccgg caccuacaac gugacccuga aggucaccga cgacaaaggc     2340

gcgacggcca ccgagagcuu caccaucgag aucaagaacg aggacaccac gacccccauc     2400

accaaggaga uggagccgaa cgacgacauc aaggaggcca acgggcccau cguggagggc     2460

gugaccguca agggggaccu caacggcucc gacgacgcag acacguucua cuucgaugug     2520

aaggaggacg gggacgugac caucgagcug cccuacagcg gcuccagcaa cuucaccugg     2580

cuggucuaca aggagggcga cgaccagaac cacaucgcgu ccgggaucga caagaacaac     2640

agcaaggugg gcaccuucaa gagcacgaag gggcgccacu acguguucau cuacaagcac     2700

gacuccgcca gcaacaucuc cuacagccuc aacaucaagg gccuggggaa cgagaagcug     2760

aaggagaagg agaacaacga cuccagcgac aaggccaccg ucauccccaa cuucaacacc     2820

accaugcagg gcucccuccu gggcgacgac agccgggacu acuacuccuu cgaggugaag     2880

gaggaggggg aggugaacau cgagcuggac aagaaggacg aguucggcgu cacguggacc     2940

cuccacccgg aauccaacau aaacgaccgc aucaccuacg gccaggugga cgggaacaag     3000

guguccaaca aggucaagcu gcggcccggc aaguacuacc ugcucgugua caaguacagc     3060

ggguccggaa acuacgagcu gcgcgugaac aagugaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  2315
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt11)

<400>  2315
gggagaaagc uuaccaugaa gugggugacc uucaucagcc uccucuuccu guucuccagc       60

gccuacucca ugaagaagaa cauccugaag auccucaugg acagcuacuc caaggagagc      120

aagauccaga ccguccgccg ggugacgucc gugagccugc uggccgucua ccucaccaug      180

aacaccucca gccuggugcu ggcgaagccc aucgagaaca ccaacgacac guccaucaag      240

aacguggaga agcuccgcaa cgccccgaac gaggagaaca gcaagaaggu cgaggacucc      300

aagaacgaca agguggagca cgugaagaac aucgaggagg ccaaggucga gcaggucgcc      360

cccgagguca agagcaaguc cacccugcgg agcgccuccc gccggcgccg gaagcgcauc      420

gcgaacacca acagcgagaa guacgacuuc gaguaccuga acggccucuc cuacaccgag      480

cugacgaacc ugaucaagaa caucaagugg aaccagauca acgggcuguu caacuacagc      540

accggcagcc agaaguucuu cggggacaag aaccgggugc aggccaucau caacgcccug      600

caggaguccg gccgcaccua caccgccaac gacaugaagg ggaucgagac guucaccgag      660

gugcugcggg cgggcuucua ccucggcuac uacaacgacg ggcugagcua ccugaacgac      720

cgcaacuucc aggacaagug cauccccgcc augaucgcca uccagaagaa ccccaacuuc      780

aagcucggca ccgccgugca ggacgaggug aucaccuccc uggggaagcu gaucggcaac      840

gccagcgcga acgccgaggu ggugaacaac ugcgucccgg ugcucaagca guuccgggag      900

aaccugaacc aguacgcccc cgacuacgug aaggggacgg ccgucaacga gcugaucaag      960

ggcaucgagu ucgacuucuc cggcgccgcg uacgagaagg acgugaagac caugcccugg     1020

uacgggaaga ucgaccccuu caucaacgag cucaaggccc ugggccugua cgggaacauc     1080

accagcgcca ccgagugggc cuccgacgug ggcaucuacu accucagcaa guucggccug     1140

uacuccacga accgcaacga caucguccag agccuggaga aggccgugga cauguacaag     1200

uacgggaaga ucgcguucgu cgccauggag cggaucaccu gggacuacga cggcaucggg     1260

uccaacggca agaaggugga ccacgacaag uuccucgacg acgccgagaa gcacuaccug     1320

ccgaagaccu acaccuucga caacgggacg uucaucaucc gcgccggcga caaggugagc     1380

gaggagaaga ucaagcggcu guacugggcc ucccgcgagg ucaagagcca guuccaccgg     1440

guggugggca acgacaaggc gcucgagguc gggaacgccg acgacgugcu gaccaugaag     1500

aucuucaacu cccccgagga guacaaguuc aacaccaaca ucaacggcgu gagcaccgac     1560

aacgggggcc uguacaucga gccccgcggg acguucuaca ccuacgagcg gacgccccag     1620

caguccaucu ucagccucga ggagcuguuc cgccacgagu acacccacua ccugcaggcc     1680

cgcuaccucg ucgacggccu guggggccag gggccguucu acgagaagaa ccggcugacc     1740

ugguucgacg agggcaccgc cgaguucuuc gcggggucca cccgcaccag cggcgugcuc     1800

ccccgcaaga gcauccuggg guaccuggcc aaggacaagg uggaccaccg guacucccuc     1860

aagaagacgc ugaacagcgg cuacgacgac uccgacugga uguucuacaa cuacggcuuc     1920

gccgucgccc acuaccugua cgagaaggac augcccaccu ucaucaagau gaacaaggcc     1980

auccugaaca ccgacgucaa gagcuacgac gagaucauca agaagcucuc cgacgacgcg     2040

aacaagaaca ccgaguacca gaaccacauc caggagcugg ccgacaagua ccagggggcc     2100

ggcauccccc uggugagcga cgacuaccuc aaggaccacg gguacaagaa ggccuccgag     2160

guguacagcg agaucuccaa ggccgcgagc cugaccaaca cguccgugac cgccgagaag     2220

ucccaguacu ucaacaccuu cacccugcgg ggcacguaca ccggcgagac cagcaagggg     2280

gaguucaagg acugggacga gaugagcaag aagcucgacg gcacccugga gucccuggcc     2340

aagaacagcu gguccgggua caagacgcuc accgccuacu ucaccaacua ccgcgugacc     2400

agcgacaaca agguccagua cgacguggug uuccacggcg uccugacgga caacgccgac     2460

aucagcaaca acaaggcgcc gaucgccaag gugaccgggc ccuccaccgg cgccgugggc     2520

cggaacaucg aguucagcgg gaaggacucc aaggacgagg acggcaagau cgucagcuac     2580

gacugggacu ucggggacgg cgccaccucc cgcgggaaga acagcgugca cgcguacaag     2640

aaggccggca cguacaacgu gacccugaag gucaccgacg acaagggcgc caccgccacg     2700

gaguccuuca ccaucgagau caagaacgag gacaccacca cgcccaucac caaggagaug     2760

gagcccaacg acgacaucaa ggaggccaac gggccgaucg uggagggcgu gaccgucaag     2820

ggggaccuca acggcagcga cgacgcggac accuucuacu ucgacgugaa ggaggacggg     2880

gacgugacga ucgagcugcc cuacuccggc agcuccaacu ucaccuggcu ggucuacaag     2940

gagggcgacg accagaacca caucgccagc gggaucgaca agaacaacuc caaggugggc     3000

accuucaaga gcaccaaggg gcggcacuac guguucaucu acaagcacga cuccgccagc     3060

aacaucuccu acagccucaa caucaagggc cuggggaacg agaagcugaa ggagaaggag     3120

aacaacgacu ccagcgacaa ggccacgguc auccccaacu ucaacaccac caugcagggc     3180

agccuccugg gcgacgacuc ccgcgacuac uacagcuucg aggugaagga ggagggggag     3240

gugaacaucg agcuggacaa gaaggacgag uucggcguca ccuggacgcu ccaccccgag     3300

uccaacauca acgaccggau caccuacggc cagguggacg ggaacaaggu gagcaacaag     3360

gucaagcugc gcccgggcaa guacuaccug cucguguaca aguacuccgg gagcggcaac     3420

uacgagcugc gggugaacaa gugaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  2316
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt11)

<400>  2316
gggagaaagc uuaccaugaa cuuccugaag aucauccuca accgcggcaa gaccaugaag       60

cggaagugcc ugagcaagcg ccugaugcuc gccaucacca uggccacgau cuucaccgug      120

aacuccaccc ugcccaucua cgcggccguc gacaagaaca acgccaccgc cgccgugcag      180

aacgagagca agcgguacac gguguccuac cugaagaccc ucaacuacua cgaccugguc      240

gaccugcucg ugaagaccga gaucgagaac cugccggacc uguuccagua cagcuccgac      300

gcgaaggagu ucuacgggaa caagacccgc augagcuuca ucauggacga gaucggccgg      360

cgcgcgcccc aguacacgga gaucgaccac aaggggaucc ccacccucgu ggaggucgug      420

cgggccggcu ucuaccuggg guuccacaac aaggagcuga acgagaucaa caagcgcucc      480

uucaaggagc gggugauccc cagcauccuc gccauccaga agaacccgaa cuucaagcug      540

ggcaccgagg uccaggacaa gaucgugucc gccaccggcc ugcucgccgg gaacgagacg      600

gccccgcccg agguggucaa caacuucacc cccauccugc aggacugcau caagaacauc      660

gaccgcuacg cccuggacga ccucaagagc aaggcccugu ucaacgugcu ggcggccccg      720

accuacgaca ucaccgagua ccuccgggcc acgaaggaga agcccgagaa cacccccugg      780

uacggcaaga ucgacggguu caucaacgag cugaagaagc uggcccucua cggcaagauc      840

aacgacaaca acuccuggau caucgacaac gggaucuacc acaucgcgcc ccugggcaag      900

cugcacagca acaacaagau cggcaucgag acccucaccg aggugaugaa ggucuacccg      960

uaccugucca ugcagcaccu ccagagcgcc gaccagauca agcgccacua cgacuccaag     1020

gacgccgagg ggaacaagau cccccuggac aaguucaaga aggagggcaa ggagaaguac     1080

ugccccaaga cguacaccuu cgacgacggg aaggugauca ucaaggccgg cgcccgggug     1140

gaggaggaga aggucaagcg ccuguacugg gccagcaagg aggugaacuc ccaguucuuc     1200

cggguguacg gcaucgacaa gccccuggag gaggggaacc cggacgacau ccucaccaug     1260

gucaucuaca acagccccga ggaguacaag cugaacuccg ugcuguacgg cuacgacacc     1320

aacaacgggg gcauguacau cgagcccgag gggacguucu ucaccuacga gcgcgaggcg     1380

caggagagca ccuacacccu cgaggagcug uuccggcacg aguacacgca cuaccugcag     1440

ggccgcuacg ccgugcccgg ccaguggggg cggaccaagc ucuacgacaa cgaccgccug     1500

accugguacg aggagggcgg ggccgagcug uucgccggca gcacccggac guccgggauc     1560

cucccgcgca agagcaucgu cuccaacauc cacaacacca cccgcaacaa ccgguacaag     1620

cugagcgaca ccgugcacuc caaguacggc gccagcuucg aguucuacaa cuacgcgugc     1680

auguucaugg acuacaugua caacaaggac augggcaucc ugaacaagcu caacgaccug     1740

gccaagaaca acgacgucga cggguacgac aacuacaucc gcgaccuguc cagcaacuac     1800

gcccugaacg acaaguacca ggaccacaug caggagcgga ucgacaacua cgagaaccuc     1860

acggugcccu ucguggccga cgacuaccug guccgccacg cguacaagaa ccccaacgag     1920

aucuacuccg agaucagcga gguggccaag cugaaggacg ccaaguccga ggugaagaag     1980

ucccaguacu ucagcaccuu cacccuccgg ggcagcuaca ccgggggcgc cuccaagggg     2040

aagcuggagg accagaaggc caugaacaag uucaucgacg acagccugaa gaagcucgac     2100

accuacuccu ggagcggcua caagacgcug accgcguacu ucaccaacua caaggucgac     2160

uccagcaacc gcgugaccua cgacgugguc uuccacggcu accugcccaa cgagggggac     2220

agcaagaacu cccucccgua cggcaagauc aacgggacgu acaagggcac cgagaaggag     2280

aagaucaagu ucagcuccga gggcagcuuc gaccccgacg ggaagaucgu guccuacgag     2340

ugggacuucg gcgacgggaa caagagcaac gaggagaacc ccgagcacuc cuacgacaag     2400

gugggcaccu acaccgucaa gcugaaggug acggacgaca agggggagag cuccgugagc     2460

accaccaccg ccgagaucaa ggaccugucc gagaacaagc uccccgucau cuacaugcac     2520

gugcccaaga gcggcgcccu gaaccagaag guggucuucu acggcaaggg gacguacgac     2580

cccgacggcu ccaucgccgg guaccagugg gacuucggcg acgggagcga cuucuccagc     2640

gagcagaacc ccucccacgu guacaccaag aagggcgagu acaccgugac ccugcggguc     2700

auggacagca gcggccagau guccgagaag acgaugaaga ucaagaucac cgacccggug     2760

uaccccaucg ggaccgagaa ggagcccaac aacagcaagg agaccgccuc cggccccauc     2820

gugccgggga uccccgucag cggcacgauc gagaacaccu ccgaccagga cuacuucuac     2880

uucgacguga ucacccccgg ggaggugaag aucgacauca acaagcucgg cuacggcggg     2940

gcgaccuggg ucguguacga cgagaacaac aacgccguga gcuacgccac ggacgacggc     3000

cagaaccugu ccgggaaguu caaggccgac aagcccggcc gcuacuacau ccaccuguac     3060

auguucaacg ggagcuacau gccguaccgg aucaacaucg agggcuccgu cggccgcuga     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  2317
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt11)

<400>  2317
gggagaaagc uuaccaugaa gcgcaagugc cugagcaagc ggcucaugcu ggccaucacc       60

auggccacca ucuucacggu gaacuccacc cugcccaucu acgcggccgu cgacaagaac      120

aacgccaccg ccgccgugca gaacgagagc aagcgcuaca ccguguccua ccucaagacg      180

cugaacuacu acgaccuggu cgaccuccug gugaagaccg agaucgagaa ccugccggac      240

cucuuccagu acagcuccga cgcgaaggag uucuacggca acaagacccg gaugagcuuc      300

aucauggacg agaucgggcg ccgggcgccc caguacaccg agaucgacca caagggcauc      360

cccacgcugg uggaggucgu gcgcgccggg uucuaccugg gcuuccacaa caaggagcuc      420

aacgagauca acaagcgguc cuucaaggag cgcgugaucc ccagcauccu ggccauccag      480

aagaacccga acuucaagcu ggggaccgag guccaggaca agaucguguc cgccaccggc      540

cuccuggccg gcaacgagac cgccccgccc gaggugguca acaacuucac gcccauccug      600

caggacugca ucaagaacau cgaccgguac gcccucgacg accucaagag caaggcccug      660

uucaacgugc ucgcggcccc gaccuacgac aucaccgagu accugcgcgc caccaaggag      720

aagcccgaga acacgcccug guacgggaag aucgacggcu ucaucaacga gcugaagaag      780

cucgcccugu acgggaagau caacgacaac aacuccugga ucaucgacaa cggcaucuac      840

cacaucgcgc cccuggggaa gcuccacagc aacaacaaga ucggcaucga gacccugacc      900

gaggugauga aggucuaccc guaccugucc augcagcacc uccagagcgc cgaccagauc      960

aagcggcacu acgacuccaa ggacgccgag ggcaacaaga ucccccugga caaguucaag     1020

aaggagggga aggagaagua cugccccaag accuacacgu ucgacgacgg caaggugauc     1080

aucaaggccg gggcccgcgu ggaggaggag aaggucaagc ggcuguacug ggccagcaag     1140

gaggugaacu cccaguucuu ccgcguguac ggcaucgaca agccccucga ggagggcaac     1200

ccggacgaca uccugaccau ggucaucuac aacagccccg aggaguacaa gcugaacucc     1260

gugcucuacg gguacgacac caacaacggc gggauguaca ucgagcccga gggcaccuuc     1320

uucacguacg agcgggaggc gcaggagagc accuacaccc uggaggagcu guuccgccac     1380

gaguacaccc acuaccucca ggggcgguac gccgugcccg gccagugggg ccgcacgaag     1440

cuguacgaca acgaccggcu gaccugguac gaggagggcg gggccgagcu guucgccggg     1500

agcacccgca ccuccggcau ccugccgcgc aagagcaucg ucuccaacau ccacaacacg     1560

acccggaaca accgcuacaa gcugagcgac accgugcacu ccaaguacgg ggccagcuuc     1620

gaguucuaca acuacgcgug cauguucaug gacuacaugu acaacaagga caugggcauc     1680

cucaacaagc ugaacgaccu ggccaagaac aacgacgucg acggcuacga caacuacauc     1740

cgggaccucu ccagcaacua cgcccugaac gacaaguacc aggaccacau gcaggagcgc     1800

aucgacaacu acgagaaccu gaccgugccc uucguggccg acgacuaccu gguccggcac     1860

gcguacaaga accccaacga gaucuacucc gagaucagcg agguggccaa gcucaaggac     1920

gccaaguccg aggugaagaa gucccaguac uucagcacgu ucacccugcg cgggagcuac     1980

accggcgggg ccuccaaggg caagcuggag gaccagaagg ccaugaacaa guucaucgac     2040

gacagccuca agaagcugga caccuacucc uggagcgggu acaagacccu gacggcguac     2100

uucaccaacu acaaggucga cuccagcaac cgggugaccu acgacguggu cuuccacggc     2160

uaccucccca acgagggcga cagcaagaac ucccugccgu acgggaagau caacggcacc     2220

uacaagggga cggagaagga gaagaucaag uucagcuccg agggcagcuu cgaccccgac     2280

ggcaagaucg uguccuacga gugggacuuc ggggacggca acaagagcaa cgaggagaac     2340

cccgagcacu ccuacgacaa gguggggacc uacaccguca agcugaaggu gaccgacgac     2400

aagggcgaga gcuccgugag cacgaccacc gccgagauca aggaccucuc cgagaacaag     2460

cugcccguca ucuacaugca cgugcccaag agcggggccc ugaaccagaa gguggucuuc     2520

uacggcaagg gcaccuacga ccccgacggg uccaucgccg gcuaccagug ggacuucggg     2580

gacggcagcg acuucuccag cgagcagaac cccucccacg uguacacgaa gaagggggag     2640

uacaccguga cccuccgcgu cauggacagc agcggccaga uguccgagaa gaccaugaag     2700

aucaagauca cggacccggu guaccccauc ggcaccgaga aggagcccaa caacagcaag     2760

gagaccgccu ccgggcccau cgugccgggc auccccguca gcgggaccau cgagaacacg     2820

uccgaccagg acuacuucua cuucgacgug aucacccccg gcgaggugaa gaucgacauc     2880

aacaagcugg gguacggcgg cgcgaccugg gucguguacg acgagaacaa caacgccgug     2940

agcuacgcca ccgacgacgg gcagaaccug uccggcaagu ucaaggccga caagcccggg     3000

cgguacuaca uccaccucua cauguucaac ggcagcuaca ugccguaccg caucaacauc     3060

gagggguccg ucggccggug aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  2318
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt11)

<400>  2318
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ugcuguuccu guucuccagc       60

gccuacuccg uccagaacga gagcaagcgc uacaccgugu ccuaccugaa gacgcucaac      120

uacuacgacc ugguggaccu gcucgucaag accgagaucg agaaccugcc cgaccuguuc      180

caguacagcu ccgacgccaa ggaguucuac ggcaacaaga cccggaugag cuucaucaug      240

gacgagaucg ggcgccgggc gccgcaguac accgagaucg accacaaggg cauccccacg      300

cucguggagg ugguccgcgc cggguucuac cugggcuucc acaacaagga gcugaacgag      360

aucaacaagc gguccuucaa ggagcgcgug auccccagca uccucgccau ccagaagaac      420

cccaacuuca agcuggggac cgaggugcag gacaagaucg ucuccgccac cggccugcuc      480

gccggcaacg agaccgcgcc gcccgaggug gugaacaacu ucacgcccau ccugcaggac      540

ugcaucaaga acaucgaccg guacgcccug gacgaccuca agagcaaggc ccuguucaac      600

guccuggccg cgcccaccua cgacaucacc gaguaccucc gcgccaccaa ggagaagccg      660

gagaacacgc ccugguacgg gaagaucgac ggcuucauca acgagcugaa gaagcuggcc      720

cucuacggga agaucaacga caacaacucc uggaucaucg acaacggcau cuaccacauc      780

gcgccccugg ggaagcugca cagcaacaac aagaucggca ucgagacccu caccgaggug      840

augaaggugu accccuaccu guccaugcag caccuccaga gcgccgacca gaucaagcgg      900

cacuacgacu ccaaggacgc cgagggcaac aagaucccgc ucgacaaguu caagaaggag      960

gggaaggaga aguacugccc caagaccuac acguucgacg acggcaaggu caucaucaag     1020

gccggggccc gcguggagga ggagaaggug aagcggcugu acugggccag caaggagguc     1080

aacucccagu ucuuccgcgu guacggcauc gacaagcccc uggaggaggg caaccccgac     1140

gacauccuca ccauggugau cuacaacagc ccggaggagu acaagcugaa cagcguccug     1200

uacggguacg acaccaacaa cggcgggaug uacaucgagc ccgagggcac cuucuucacg     1260

uacgagcggg aggcccagga guccaccuac acccucgagg agcuguuccg ccacgaguac     1320

acccacuacc ugcaggggcg guacgcggug cccggccagu ggggccgcac gaagcucuac     1380

gacaacgacc ggcugaccug guacgaggag ggcggggccg agcuguucgc cgggagcacc     1440

cgcaccuccg gcauccuccc ccgcaagagc aucgugucca acauccacaa cacgacccgg     1500

aacaaccggu acaagcugag cgacaccguc cacuccaagu acggggccag cuucgaguuc     1560

uacaacuacg ccugcauguu cauggacuac auguacaaca aggacauggg cauccugaac     1620

aagcucaacg accuggcgaa gaacaacgac guggacggcu acgacaacua cauccgcgac     1680

cuguccagca acuacgcccu caacgacaag uaccaggacc acaugcagga gcgcaucgac     1740

aacuacgaga accugaccgu cccguucgug gccgacgacu accuggugcg gcacgccuac     1800

aagaacccca acgagaucua cuccgagauc agcgaggucg ccaagcugaa ggacgcgaag     1860

uccgagguga agaaguccca guacuucagc acguucaccc uccgcgggag cuacaccggc     1920

ggggccucca agggcaagcu ggaggaccag aaggccauga acaaguucau cgacgacagc     1980

cugaagaagc ucgacaccua cuccuggagc ggguacaaga cgcugaccgc cuacuucacc     2040

aacuacaagg uggacagcuc caaccggguc accuacgacg ugguguucca cggcuaccug     2100

cccaacgagg gcgacagcaa gaacucccuc cccuacggga agaucaacgg caccuacaag     2160

gggacggaga aggagaagau caaguucagc uccgagggca gcuucgaccc ggacggcaag     2220

aucgucuccu acgaguggga cuucggggac ggcaacaaga gcaacgagga gaaccccgag     2280

cacuccuacg acaagguggg gaccuacacc gugaagcuga aggucaccga cgacaagggc     2340

gagagcuccg ugagcacgac caccgcggag aucaaggacc uguccgagaa caagcucccc     2400

gugaucuaca ugcacguccc caagagcggg gcccugaacc agaagguggu guucuacggc     2460

aagggcaccu acgacccgga cggguccauc gccggcuacc agugggacuu cggggacggc     2520

agcgacuucu ccagcgagca gaaccccagc cacgucuaca cgaagaaggg ggaguacacc     2580

gugacccugc gcgugaugga cuccagcggc cagauguccg agaagaccau gaagaucaag     2640

aucacggacc ccgucuaccc gaucggcacc gagaaggagc ccaacaacag caaggagacc     2700

gccuccgggc ccaucgugcc cggcaucccg gugagcggga ccaucgagaa cacguccgac     2760

caggacuacu ucuacuucga cgucaucacc cccggcgagg ugaagaucga caucaacaag     2820

cucggguacg gcggcgccac cugggugguc uacgacgaga acaacaacgc ggugagcuac     2880

gccaccgacg acgggcagaa ccuguccggc aaguucaagg ccgacaagcc cgggcgguac     2940

uacauccacc uguacauguu caacggcagc uacaugcccu accgcaucaa caucgagggg     3000

uccgugggcc ggugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2319
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt11)

<400>  2319
gggagaaagc uuaccaugaa gugggugacc uucaucagcc ucuuauuccu guuuuccagu       60

gccuacucca ugaagcgcaa gugccugagc aagcggcuca ugcuggccau caccauggcg      120

acgaucuuca ccgucaacuc cacccugccc aucuacgccg ccguggacaa gaacaacgcc      180

accgccgcgc gccggcgccg gaagcgcgug cagaacgaga gcaagcggua cacggucucc      240

uaccucaaga cccugaacua cuacgaccug guggaccucc uggugaagac cgagaucgag      300

aaccugccgg accucuucca guacagcuca gacgccaagg aguucuacgg caacaagacc      360

cgcaugagcu ucaucaugga cgagaucggg cggcgcgcgc cccaguacac ggagaucgac      420

cacaagggca uucccacccu ggucgaggug gugcgggccg gguucuaccu gggcuuccac      480

aacaaggagc ucaaugagau caacaagcgc uccuucaagg agcgagucau cccaagcauc      540

cuggccaucc agaagaaccc gaacuucaag cuggggaccg aggugcagga caagaucgug      600

uccgccaccg gccuccucgc cggcaacgag acggccccgc ccgaggucgu gaauaacuuc      660

acccccaucc ugcaggacug caucaagaac aucgaccgcu acgcccucga cgaccucaag      720

agcaaggcgc uguucaacgu ccuggcagcc ccgacauacg acaucaccga guaccuccgg      780

gccacuaagg agaagcccga gaacaccccc ugguacggga agaucgacgg cuucaucaac      840

gagcugaaga aacucgcccu guacgggaag aucaacgaca acaacuccug gaucaucgac      900

aacggcaucu accacaucgc gccccugggg aagcuccaca gcaacaacaa gaucggcauc      960

gagaccuuga ccgaggucau gaagguguac ccguaccugu ccaugcagca ccuccaaagc     1020

gccgaccaga ucaagcgcca cuacgacucc aaggacgccg agggcaacaa gaucccccuu     1080

gacaaguuca agaaggaggg gaaggagaaa uacugcccca agacguacac cuucgacgac     1140

ggcaagguga ucaucaaggc cggggcccgg gucgaggagg agaaggugaa gcgguuauac     1200

ugggcgucaa aagaggugaa cagccaguuc uuccgggucu acggcaucga caagccccuc     1260

gaggagggca acccggacga cauccugacc auggugaucu acaacucccc cgaggaguac     1320

aagcugaaca gcgugcucua cggguacgac acaaacaacg gcggaaugua caucgagccc     1380

gagggcacgu ucuucacgua cgagcgcgag gcccaggagu ccaccuacac ccuggaggag     1440

cuguuccggc acgaguacac gcacuaccuc caggggagau acgccguccc cggccagugg     1500

ggccgcacca agcuguacga caacgaccgg cugaccuggu acgaggaggg aggggccgag     1560

cuguucgccg ggagcacccg cacguccggc auccugccgc gcaagagcau cguuuccaac     1620

auccauaaca ccacccggaa caacagauac aagcugagcg acaccgucca cuccaaguac     1680

ggggcgagcu ucgaguuuua caacuacgcc uguauguuca uggacuacau guacaacaag     1740

gauaugggca uacucaacaa gcugaacgac cuggccaaga auaacgacgu ggacggcuac     1800

gacaacuaca uccgcgaccu gucaagcaac uacgcccuca acgacaagua ccaggaccac     1860

augcaggagc ggaucgacaa cuacgagaac cugacggugc ccuucgucgc ggacgacuac     1920

cuggugcguc acgccuacaa gaaccccaac gagaucuacu cugagaucag ugagguggcc     1980

aagcucaagg acgccaaguc agaggucaag aagucccagu acuucagcac cuucacccug     2040

cgggggagcu auaccggcgg ggccuccaag ggcaagcugg aggaccagaa ggccaugaac     2100

aaguucaucg acgacagccu caagaagcug gacaccuaca gcugguccgg guacaagacg     2160

cugaccgcgu acuucaccaa cuacaaggug gauagcucca accgcguaac cuacgacguc     2220

guguuccacg gcuaccuccc caacgagggc gacagcaaga acucccugcc guacgggaag     2280

aucaacggca cguacaaggg gaccgagaag gagaaaauca aguucagcuc cgagggcucc     2340

uucgaccccg acggcaagau cguguccuac gagugggacu ucggggacgg caacaagagc     2400

aacgaggaga accccgaaca cuccuacgac aaggucggga ccuacaccgu gaagcugaag     2460

gugacggacg acaagggcga gagcuccguc ucuaccacca ccgccgagau caaggaccuc     2520

uccgagaaca agcugcccgu gaucuacaug cacgugccca agucaggggc ccugaaccaa     2580

aaggucgugu uuuacggcaa gggcacguac gaccccgacg gguccauagc cggcuaccag     2640

ugggacuucg gggacggcag cgacuucagc uccgagcaga accccagcca cguguacacc     2700

aagaaggggg aguacaccgu cacccucagg gugauggacu ccagcggcca gauguccgag     2760

aagacgauga agaucaagau caccgauccg guguacccca ucggcaccga gaaggagccg     2820

aacaacagca aggagaccgc guccgggccc aucgucccgg gcauccccgu gagcgggacg     2880

aucgagaaca ccuccgacca ggacuacuuc uacuucgacg ugaucacccc cggcgagguc     2940

aagaucgaua ucaacaagcu gggguacggc ggcgccaccu ggguggugua cgacgagaac     3000

aacaacgccg ucagcuacgc uacggacgac gggcagaacc uguccggcaa guucaaggcc     3060

gacaagcccg ggcgguacua cauccaccuc uacauguuca acggcagcua caugccguac     3120

cggaucaaca ucgagggguc cguaggccga ugaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  2320
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt11)

<400>  2320
gggagaaagc uuaccauggg caccuggaua cuauucgccu gccuccucgg cgccgccuuc       60

gccaugcccc uaccccccca ccccggccac cccggcuaca ucaacuucuc auacgaaguc      120

cucacccccc ucaaauggua ccaaucaauc cgcccccccu accccuccua cggcuacgaa      180

cccaugggag gcuggcucca ccaccaaauc auccccgucc ucucccaaca acaccccccc      240

acccacaccc uccaacccca ccaccacauc cccgucgucc ccgcccaaca acccgucauc      300

ccccaacaac ccaugaugcc cguccccggc caacacucaa ugacccccau ccaacaccac      360

caacccaacc uccccccccc cgcccaacaa cccuaccaac cccaacccgu ccaaccccaa      420

ccacaccaac caaugcaacc ccaacccccc guccacccca ugcaaccccu ccccccccaa      480

cccccccuac cccccauguu ccccaugcaa ccccuccccc ccaugcuccc cgaccucacc      540

cucgaagccu ggcccuccac cgacaaaacc aaacgcgaag aagucgacua aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  2321
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt11)

<400>  2321
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgaag uccucacccc ccucaaaugg uaccaaucca uccgcccccc cuaccccucc      120

uacggcuacg aacccauggg cggcugguaa ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  2322
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt11)

<400>  2322
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgaag uccucacccc ccucaaaugg uaccaaucca uccgcccccc ccccaugcuc      120

cccgaccuca cccucgaagc cuggcccucc accgacaaaa ccaaacgcga agaagucgac      180

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  2323
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt11)

<400>  2323
gggagaaagc uuaccauggc cgucauggcc ccccgcaccc ucguccuccu ccucuccggc       60

gcccucgccc ucacccaaac cugggccaug ccccuccccc cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga aguccucacc ccccucaaau gguaccaauc cauccgcccc      180

cccuaccccu ccuacggcua cgaacccaug ggcggcuggu aaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  2324
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt11)

<400>  2324
gggagaaagc uuaccauggc cgucauggcc ccccgcaccc ucguccuacu ccucuccggc       60

gcccucgccc ucacccaaac cugggccaug ccccuccccc cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga aguccucacc ccccucaaau gguaccaauc cauccgcccc      180

ccccccaugc uccccgaccu cacccucgaa gccuggcccu ccaccgacaa aaccaaacgc      240

gaagaagucg acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  2325
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt11)

<400>  2325
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccucgucgg cgccgccuuc       60

gcaaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc      120

cucaccccac ucaaauggua ccaauccaug auccgcccac ccuacucauc cuacggcuac      180

gaaccaaugg gcggcuggcu ccaccaccaa aucauccccg ucguauccca acaacacccc      240

cucacccaca cccuccaauc ccaccaccac auccccgucg uccccgcaca acaaccccgc      300

guccgccaac aagcccucau gcccgucccc ggccaacaau ccaugacccc cacccaacac      360

caccaaccca accucccccu ccccgcccaa caacccuucc aaccccaacc cguccaaccc      420

caaccccacc aacccaugca accccaaccc ccaguccaac ccaugcaacc ccuccucccc      480

caaccccccc ucccccccau guucccacuc cgaccccucc cccccauccu acccgaccuc      540

caccuugaag ccuggcccgc caccgacaaa accaaacaag aagaagucga cuaaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  2326
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt11)

<400>  2326
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgaag uccucacccc ccucaaaugg uaccaaucca ugauccgccc ccccuacucc      120

uccuacggcu acgaacccau gggcggcugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  2327
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt11)

<400>  2327
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgaag uccucacccc ccucaaaugg uaccaaucca ugauccgccc cccccccauc      120

cuccccgacc uccaccucga agccuggccc gccaccgaca aaaccaaaca agaagaaguc      180

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  2328
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt11)

<400>  2328
gggagaaagc uuaccauggc cgucauggcc ccccgcaccc ucguccuccu ccucuccggc       60

gcccucgccc ucacccaaac cugggccaug ccccuccccc cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga aguccucacc ccccucaaau gguaccaauc caugauccgc      180

ccccccuacu ccuccuacgg cuacgaaccc augggcggcu gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  2329
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt11)

<400>  2329
gggagaaagc uuaccauggc cgucauggcc ccccgcaccc ucguccuccu ccucuccggc       60

gcccucgccc ucacccaaac cugggccaug ccccuccccc cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga aguccucacc ccccucaaau gguaccaauc caugauccgc      180

ccccccccca uccuccccga ccuccaccuc gaagccuggc ccgccaccga caaaaccaaa      240

caagaagaag ucgacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  2330
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt11)

<400>  2330
gggagaaagc uuaccauggg caccuggauc cucuucgccu gucuccucgg cgccgccuuc       60

uccaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc      120

cucacccccc ucaaauggua ccaaaacaug auccgacacc ccuacaccuc cuacggcuac      180

gaacccaugg gcggcuggcu ccaccaccaa aucauccccg ucgucuccca acaaaccccc      240

caaucccacg cccuucaacc ccaccaccac auccccaugg uccccgccca acaacccggc      300

auaccccaac aacccaugau gccccucccu ggccaacacu ccaugacccc cacccaacac      360

caccaaccca accucccccu ccccgcccaa caacccuucc aaccccaacc cguccaaccc      420

caaccccacc aaccccucca accccaaucc cccaugcacc ccauccaacc ccuccucccc      480

caaccacccc uaccccccau guucuccaug caaucccucc uccccgaccu cccccucgaa      540

gccuggcccg ccaccgacaa aacaaaacgu gaagaagucg acuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  2331
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt11)

<400>  2331
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgaag uccucacccc ccucaaaugg uaccaaaaca ugauccgcca ccccuacacc      120

uccuacggcu acgaacccau gggcggcugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  2332
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt11)

<400>  2332
gggagaaagc uuaccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc       60

uccuacgaag uccucacccc ccucaaaugg uaccaaaaca ugauccgcca ccccucccuc      120

cuccccgacc ucccccucga agccuggccc gccaccgaca aaaccaaacg cgaagaaguc      180

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  2333
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt11)

<400>  2333
gggagaaagc uuaccauggc cgucauggcc ccccgcaccc ucguccuccu ccucuccggc       60

gcccucgccc ucacccaaac cugggccaug ccccuccccc cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga aguccucacc ccccucaaau gguaccaaaa caugauccgc      180

caccccuaca ccuccuacgg cuacgaaccc augggcggcu gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  2334
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt11)

<400>  2334
gggagaaagc uuaccauggc cgucauggcc ccccgcaccc ucguccuccu ccucuccggc       60

gcccucgccc ucacccaaac cugggccaug ccccuccccc cccaccccgg ccaccccggc      120

uacaucaacu ucuccuacga aguccucacc ccccucaaau gguaccaaaa caugauccgc      180

caccccuccc uccuccccga ccucccccuc gaagccuggc ccgccaccga caaaaccaaa      240

cgcgaagaag ucgacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  2335
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt11)

<400>  2335
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccuccucgg cgccgccuuc       60

uccaugcccc ucccccccca ccccggccac cccggauaca ucaacuucuc cuacauccga      120

caccccuaca ccuccuacgg cuacgaaccc augggcggcu ggcuccacca ccaaaucauc      180

cccgucgucu cccaacaaac cccccaaucc cacgcccucc aaccacacca ccacaucccc      240

augguccccg cccaacaacc cggcaucccc caacaaccca ugaugccccu ccccggccaa      300

cacuccauga cccccaccca acaccaccaa cccaaccucc cccuucccgc ccaacaaccc      360

uuccaacccc aacccgucca accccaaccc caccaacccc uacaacccca aucccccaug      420

caccccaucc aaccccuccu cccccaaccc ccccuacccc ccauguucuc caugcaaucc      480

cuccuccccg accucccccu cgaagccugg cccgccaccg acaaaaccaa acgcgaagaa      540

gucgacuaag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  2336
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt11)

<400>  2336
gggagaaagc uuaccauggg caccuggauc uucuucgccu gccuccucgg cgccucccuc       60

gccaugcccc ucccacccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc      120

cucacacccc ucaaauggua ccaaaacaug auccgccacc ccuacaccuc cuacggcuac      180

gaacccaugg gcggcuggcu ccaccaccaa aucauccccg ucgucucuca acaaacaccc      240

caaucccacg cccuccaacc ccaccaccac auccccaugg uccccgccca acaacccggc      300

auaccccaac aacccaugau gccccucccc ggccaacacu ccaugacccc cacccaacac      360

caccaaccca accucccccu ccccgcccaa caacccuucc aaccccaacc cguccaaccc      420

caaccccacc aaccccucca accccaaucc cccaugcacc ccauccaacc ccuacucccc      480

caaccacccc uaccacccau guucuccaug caaucccucc uccccgaccu cccccucgaa      540

gccuggcccg ccaccgacaa aaccaaacgc gaagaagucg acuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  2337
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt11)

<400>  2337
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccuccucgg cgccgccuuc       60

uccaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc      120

cucacccccc ucaaauggua ccaaaacaug auccgccacc ccucccuccu ccccgaccuc      180

ccccucgaag ccuggcccgc caccgacaaa accaaacgcg aagaagucga cuaaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  2338
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt11)

<400>  2338
gggagaaagc uuaccauggg caccuggauc cucuucgccu gccuccucgg agccgccuuc       60

uccaugcccc uaccccccca ccccggccac cccggcuaca ucaacuucuc cuacgaagac      120

cuuuaccucg aagccauccg caucgaccgc accgccuucg uccucacccc ccuaaaaugg      180

uaccaaaaca ugauccgcca ccccuacacc uccuacggcu acgaacccau gggcggcugg      240

cuccaccacc aaaucauccc cgucgucucc caacaaaccc cccaauccca cgcccuccaa      300

ccccaccacc acauccccau gguccccgcc caacaacccg gcauccccca acaacccaug      360

augccccucc ccggccaaca cuccaugacc cccacccaac accaccaacc caaccucccc      420

cuccccgccc aacaacccuu ccaaccccaa cccguacaac cccagcccca ccaaccccuu      480

caaccccaau cccccaugca ccccauccaa ccccuccucc cccaaccccc ccuacccccc      540

auguucucca ugcaaucccu ccuccccgac cucccccucg aagccuggcc cgccaccgac      600

aaaaccaaac gcgaagaagu cgacuaagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  2339
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt11)

<400>  2339
gggagaaagc uuaccauggg aaccuggauc cucuucgccu gccuccucgg cgcagccuuc       60

uccaugcccc ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc      120

cucacccccc uaaaauggua ccaaaacaug auccgccacc ccacacccca aucacacgcc      180

cuccaacccc accaccacau ccccaugguc cccgcacaac aacccggcau cccccaacaa      240

cccaugaugc cccuccccgg ccaacacucc augacaccca cccaacacca ccaacccaac      300

cuaccccucc ccgcccaaca acccuuccaa ccccaacccg uccaacccca accccaccaa      360

ccccuccaac cccaaucccc caugcacccc auccaacccc uccuccccca acccccccuc      420

ccacccaugu ucuccaugca aucccuccuc cccgaccucc cacucgaagc cuggcccgcc      480

accgacaaaa ccaaacgcga agaagucgac uaaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  2340
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt11)

<400>  2340
gggagaaagc uuaccaugcc ccuaccccca caccccggcc accccggcua caucaacuuc       60

uccuacgaag uccucacccc acucaaaugg uaccaaaaca ugauccgcca ccccuacacc      120

uccuacggcu acgaacccau gggcggcugg cuccaccacc aaaucauccc cgucgucucc      180

caacaaaccc cacaauccca cgcccuccaa ccccaccacc acauccccau gguccccgcc      240

caacaacccg gcauccccca acaacccaug augccccucc ccggccaaca cuccaugacc      300

cccacccaac accaccaacc caaccuaccc cuccccgccc aacaacccuu ccaaccccaa      360

ccaguccaac cccaacccca ccaaccccuc caaccccaau cccccaugca cccaauccaa      420

ccccuacucc cccaaccucc ccuaccaccc auguucucca ugcaaucccu ccuccccgac      480

cucccccucg aagccuggcc cgccaccgac aaaaccaaac gcgaagaagu cgacuaagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  2341
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt11)

<400>  2341
gggagaaagc uuaccaugcc aggaguugcc cgccuaccac uacuacuagg ucuccucuua       60

cucccgcgac ccggccgccc acucgaccua gcagacuaca cauacgaccu cgcagaagaa      120

gacgacucag aaccacuaaa cuacaaagau cccugcaaag ccgcggcauu ccucggagac      180

auagcccugg acgaagaaga ucuacgagca uuccaggucc aacaagcagu agaccuccgg      240

cgacacacag cucgcaaauc guccaucaaa gcggccgucc caggcaacac aaguaccccu      300

uccugccagu ccaccaacgg ucaaccccaa cggggagccu gcggacgcug gcguggcagg      360

ucacgauccc ggcgagcagc caccagcaga ccggaacgag uauggcccga cggggucauc      420

ccauucguaa ucggugggaa cuucacggga ucgcaacgag caguauuccg acaggccaug      480

cgccacuggg aaaaacacac augcgucacc uuccucgaac gcacagacga agacagcuac      540

auagucuuca cauacagacc augcggaugc ugcaguuacg ucggacggag aggcggcggc      600

ccgcaagcaa uaucgauagg gaaaaacugc gacaaauucg gcauagucgu ccacgaacua      660

gggcaugucg uaggguucug gcacgagcac accaggcccg accgagaccg ccacguaagc      720

auaguccgcg aaaacaucca acccggacag gaauacaacu uccucaagau ggaaccccaa      780

gaagucgagu cgcuggggga aacauacgac uucgacucca uaaugcacua cgcccgaaac      840

accuucagcc gagguaucuu ccucgacaca aucgucccca aguacgaagu caacggcguc      900

aaacccccaa uaggccaacg gacccgacuc ucaaaaggug acaucgcuca ggcccgcaaa      960

cuguauaagu gccccgccug uggggagacc cuacaggaca gcacgggcaa cuucagcucc     1020

ccugaauacc ccaacggcua cagcgcacac augcacugcg ucuggcgcau cagugucacc     1080

ccaggagaga aaaucauccu caacuucacc ucacucgauc ucuaccgaag cagacucugu     1140

ugguacgacu acguggaggu ccgagacggg uucuggcgca aagcaccgcu ccgcggccgc     1200

uucugcggcu cuaaacuucc cgaacccauu gucagcaccg acucgagacu cugggucgag     1260

uucaggaguu ccagcaacug gguaggcaaa ggauucuuug cagucuacga agccauaugc     1320

ggcggcgacg ucaagaaaga cuacggccac auccaguccc caaacuaccc agacgacuac     1380

cgccccucca aagucugcau auggaggaua caaguaucag aaggguuuca cgucggacug     1440

acauuccaaa guuucgaaau agaacgucac gacucaugcg cguacgacua ccuggaagua     1500

cgcgacggcc auuccgaaag cagcacacua auaggccggu acuguggcua cgaaaagccc     1560

gacgacauaa aaucaacauc aagcagacug uggcuaaagu ucgucucgga cggaagcaua     1620

aacaaagcag gauucgcagu gaacuucuuu aaggaagucg acgaauguuc gcgcccaaac     1680

aggggaggcu gcgaacaaag augccuuaac acacuggggu cauauaagug cagcugcgac     1740

cccggauacg agcuugcacc agacaagcga agaugugagg ccgccugcgg aggcuuccuc     1800

acaaaacuga acggauccau cacaucaccc ggauggccaa aagaguaucc cccgaauaaa     1860

aacugcauau ggcagcuagu agcgccaacc caauaccgga ucagccucca guucgacuuc     1920

uucgaaaccg aaggcaacga cgugugcaaa uacgacuucg ucgagguacg cagcggucuu     1980

accgcggacu caaaacugca cggcaaauuc ugcggcagcg aaaaaccaga aguaaucacc     2040

agccaauaca acaacaugag agucgaauuu aaaucagaca acaccguauc caagaaaggc     2100

uucaaagccc acuucuuuuc cgauaaagac gaaugcagua aagauaacgg gggcugucag     2160

caagacugcg uuaacacauu cggaagcuac gaaugucaau gccgcagugg guucgugcug     2220

cacgacaaca aacacgacug caaagaagca ggaugcgacc auaaagucac cagcacaagc     2280

ggaacgauca cuagccccaa cuggccggac aaauacccau ccaagaaaga augcacaugg     2340

gccaucucca gcacccccgg ccaccgcguc aaauuaacau ucauggagau ggacaucgaa     2400

ucacaacccg aaugcgccua cgaccaccug gagguauucg acggccgaga cgccaaagca     2460

ccagugcucg gccgcuucug cggcuccaag aaaccagaac cagugcuagc caccggcagu     2520

cgaauguucc uccgcuucua cagugacaac aguguacaac gaaaaggauu ccaagcaagc     2580

cacgcaacag aaugcggugg ccaaguccgg gccgacguca aaacaaaaga ccuauacuca     2640

caugcucaau ucggugacaa caacuacccg ggcgguguag acugcgaaug ggucaucguc     2700

gcagaagagg gauacggggu cgaacucgug uuccaaacau ucgaagucga ggaagagaca     2760

gauuguggcu acgacuacau ggaacucuuc gacggguacg acagcaccgc ccccagacua     2820

ggccgcuacu guggaucagg uccacccgaa gaagucuaca gcgccgguga cucaguacuc     2880

gugaaauucc acagcgacga cacaauuaca aagaaaggcu uccaccuaag auacacgucc     2940

accaaauucc aggacacccu ccacagccgc aaaugaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  2342
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt11)

<400>  2342
gggagaaagc uuaccauggu cgccggcacc cguugccucc uugcccuccu ccuaccccaa       60

guccuacuag gcggagcagc cggccucguc cccgaacucg gccgccgcaa auucgccgcc      120

gccucauccg gacgccccuc cucacaaccc agcgacgaag uacucucaga auucgaacuu      180

cgucuacucu ccauguucgg ccucaaacaa cgacccacuc ccucccgcga cgcagucguc      240

cccccuuaca ugcuagaccu uuaccgccgc cacuccggcc aacccggauc acccgccccc      300

gaccaucgcc ucgaaagagc cgccucccga gccaauaccg uccgcucauu ccaccacgaa      360

gaaucacucg aagaacuacc cgaaaccagc ggaaaaacaa cacgcagauu cuucuucaac      420

cucuccagca uccccaccga agaauucauc accuccgccg aacuacaagu auucagagaa      480

caaaugcagg acgcccucgg caacaacucc agcuuccacc accgcaucaa cauauacgaa      540

auaaucaaac ccgccacagc uaacuccaag uuccccguca cacgccuacu cgacacccgc      600

cuagucaacc aaaaugccuc ccgcugggaa uccuucgacg ucacccccgc cgucaugcga      660

uggaccgcac aaggccacgc caaucacggc uucgucguag aaguugcaca ccuagaagaa      720

aaacaaggcg ucuccaaacg ccacguccgc aucuccagau cccuacacca agacgaacac      780

ucaugguccc aaauccgccc ccuccuaguc accuucggac augacggcaa aggacacccg      840

cuccacaaac gcgaaaaacg ccaagccaaa cacaaacaac gcaaacgccu caaaucaucc      900

ugcaaacgcc acccacucua cguagacuuc uccgacguag gauggaacga cuggauaguc      960

gcacccccag gcuaccacgc auucuacugc cacggagaau gcccauuccc acuugccgac     1020

caccucaacu ccaccaacca cgcuaucgua caaacacucg ucaacuccgu caacucaaaa     1080

aucccaaaag caugcugcgu ccccacagaa cucucagcca ucuccaugcu cuaccucgac     1140

gaaaacgaaa aggucguccu aaaaaacuac caagacaugg ucgucgaagg cugcggcugc     1200

cgcuagggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  2343
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt11)

<400>  2343
gggagaaagc uuaccaugau accgggcaac cgcaugcuca uggucguucu ccugugccaa       60

guccuacucg gcggcgcaag ccacgccuca cucauccccg aaacugggaa aaaaaaaguc      120

gccgaaaucc aaggccacgc cggcggaaga cgcuccggcc aaucacacga acuccuccgc      180

gacuucgaag ccacccuacu acaaauguuc ggccuccgcc gccgcccaca acccucaaag      240

agcgccguca uccccgacua caugcgcgac cuauaccgac uccaauccgg cgaagaagaa      300

gaagaacaaa uccacuccac cggacucgaa uaccccgaac gccccgccuc ccgagcaaac      360

accguacguu cuuuccacca cgaagaacac cucgaaaaua uccccggcac cuccgaaaac      420

uccgcauucc gcuuccuauu caaccucucc uccauccccg aaaacgaagu aaucucaucc      480

gcagaacucc gccuauuccg cgaacaaguc gaccaaggcc ccgacuggga aagaggcuuc      540

caccgaauaa acauuuacga agucaugaaa cccccagccg aagucguacc cggccaccuc      600

aucacacgac uucucgacac acgccuaguc caccauaacg uaacucgcug ggaaaccuuc      660

gacguaagcc ccgccguccu ccgauggacc cgugaaaaac agcccaacua cggccucgca      720

auugaaguca cccaccucca ccaaacacgc acacaccaag gccaacaugu ccgcauaucc      780

cgaucacucc cacaaggcuc cggcaacugg gcccaacucc guccacuccu cguuaccuuc      840

ggccaugacg gacgcgguca cgcccucacc agacgccgca gggccaaacg aucccccaaa      900

caucacuccc agcgcgcucg uaaaaaaaac aaaaacugcc gccgccauuc ccuauacgua      960

gacuucuccg acgucggcug gaacgacugg auagucgcac cccccggaua ccaagccuuc     1020

uacugccacg gcgacugccc cuucccacuc gcagaccacc uaaacucaac caaucacgcc     1080

aucguacaaa cccucguaaa cucagucaac uccuccauuc ccaaagccug cugcguaccc     1140

accgaacuau ccgccaucuc caugcucuac cuagacgaau acgacaaagu cguccucaaa     1200

aacuaccaag aaauggucgu cgaaggcugc ggcugccgau agggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  2344
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt11)

<400>  2344
gggagaaagc uuaccaugcc cgggcuaggc cgacgagcac aauggcuaug cugguggugg       60

ggccuacuau gcucaugcug cggaccaccu ccccuacgcc caccccugcc cgcagccgcu      120

gccgcagcug ccggcggcca acuacuaggc gacggcggcu cacccggccg aacagaacaa      180

cccccucccu cuccccaauc cucauccgga uuccuauacc gcagacucaa aacccaagaa      240

aaacgcgaaa ugcaaaaaga aauccuauca guacucggcc ugccacauag acccagaccc      300

cuccacggac uccaacaacc ccaaccuccc gcccugcguc aacaagaaga acaacaacaa      360

caacagcaac uaccccgcgg cgaaccccca cccggccgcc uaaaaucagc accccuauuu      420

augcucgacc uuuacaacgc ccucucugcc gacaaugaug aagacggcgc cuccgaaggu      480

gaacgccaac aauccuggcc ccacgaagcc gccucaucau cacaacgacg acaaccccca      540

cccggcgccg cccacccacu caaccgaaaa ucccuucucg cccccggauc ugguuccggg      600

ggcgcuuccc cacucaccuc cgcacaagac agcgccuucc uaaacgacgc cgacaugguu      660

augucauucg uaaaccuagu cgaauacgac aaagaauuuu cacccagaca aagacaccau      720

aaagaguuca aauucaaccu cucccaaauc ccagaaggcg aagucguaac agccgccgag      780

uuccgaaucu acaaagacug cgucauggga uccuucaaaa accaaaccuu ccuaauaagc      840

aucuaccaag uacuacaaga acaccaacac cgugacuccg accucuuucu ucuagacacc      900

cgaguagucu gggccucaga agaagguugg cuugaguucg acaucaccgc caccagcaac      960

cuauggguag ucacacccca acacaacaug ggacugcaac uaucagucgu aacccgcgac     1020

ggcguacacg uucacccccg agcagccgga cucguagguc gcgacggacc cuacgacaaa     1080

caacccuuca uggucgccuu cuuuaaaguc uccgaaguac acguccgaac aacacgaucc     1140

gcaucauccc gccgccgcca gcaaucccgg aaccgaucaa cacaauccca agacgucgcc     1200

cgcgucagcu cggcuucgga cuacaacucc agcgaacuaa aaacagcaug ccgcaaacac     1260

gaacuauacg ucuccuuuca agaccucgga uggcaagacu ggaucaucgc acccaaagga     1320

uacgcagcaa acuacugcga cggagaaugc uccuuccccc uaaaugcaca caugaacgca     1380

accaaccacg ccaucgucca aacccucguc caccuaauga accccgaaua uguacccaaa     1440

cccugcugcg ccccaaccaa acuaaacgca aucucaguac ucuacuucga cgacaacucc     1500

aacguaaucc ucaagaaaua ccgcaacaug guuguccgug ccugcggaug ccacuaagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  2345
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt11)

<400>  2345
gggagaaagc uuaccaugca cguccgauca cuacgcgccg cagccccaca cuccuucgua       60

gcacucuggg caccccuauu cuuacuccgc uccgcacuag ccgacuucuc ccucgacaac      120

gaaguccacu cgagcuucau ccaccgccgc cuacgguccc aagaaagacg cgaaaugcaa      180

cgcgaaaucc ucucaauucu aggacucccc caccgccccc gcccccaccu ccaaggcaaa      240

cacaacucug cccccauguu caugcucgac cucuacaacg ccauggcagu agaagaagga      300

ggcggacccg gcggccaagg cuucucauac cccuacaaag ccguuuucuc aacccaaggc      360

ccgccccucg caucccucca agacucacac uuccuaaccg acgccgacau gguaauguca      420

uucgucaacc ucguagaaca ugacaaagaa uucuuccacc cccgcuauca ccaccgcgaa      480

uuccgauucg accucucgaa aauacccgaa ggcgaagccg ugaccgcagc cgaauuccgc      540

auauacaaag acuacauccg cgaacgcuuc gacaacgaaa cauuccgcau cuccgucuac      600

caagugcucc aagaacaccu cggccgcgaa agcgaccucu uccuacuuga cucccgcaca      660

cuuugggccu cugaagaagg uuggcucgua uucgacauaa cagccaccuc aaaccacugg      720

guagucaacc cccgucacaa ccuaggacuc cagcuaucag uagaaacacu cgacggccag      780

agcaucaacc ccaaacuugc gggacucauc ggccgccacg gaccacaaaa caagcagccc      840

uucauggucg ccuucuuuaa agccaccgaa guacauuuca gauccauacg cuccaccggg      900

uccaaacaac gaucacaaaa ccgauccaaa accccaaaaa accaagaagc ucuacgaaug      960

gcaaacguag cugaaaacag cuccucagac caacgccaag ccugcaaaaa acacgaacuc     1020

uacgucuccu uccgagaccu cggcuggcaa gacuggauca ucgccccaga aggcuacgca     1080

gcauacuacu gcgaaggcga augcgccuuc ccccuuaacu cuuacaugaa cgccaccaac     1140

cacgcaaucg uccagacccu cguacacuuc aucaaccccg aaacuguccc caaacccugc     1200

ugcgccccca cccaauuaaa cgcaaucucc guccucuacu ucgacgacuc cucgaacguc     1260

auacucaaaa aauaccgaaa cauggucguc cgcgccugcg gcugccauua aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  2346
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt11)

<400>  2346
gggagaaagc uuaccaugaa agccuccgcc gcccuccucu gccuccuccu caccgccgcc       60

gccuucuccc cccaaggccu agcccaaccc gucggcauca acaccuccac caccugcugc      120

uaccgauuca ucaacaaaaa aauccccaaa caacgccucg aauccuaccg ccgcaccacc      180

uccucacacu gcccccgcga agccgucauc uucaaaacca aacucgacaa agaaaucugc      240

gccgacccca cccaaaaaug gguccaagac uucaugaaac accucgacaa aaaaacccaa      300

acccccaaac ucuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  2347
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt11)

<400>  2347
gggagaaagc uuaccaugcu gcucacgcug aucaucuuau uaccggucgu caguaaauuu       60

agcuuuguau cacugagcgc accccaacac uggucaugcc cagagggcac uuuggcaggg      120

aacggcaauu cgacgugcgu aggaccagcc ccauuccuga ucuucagcca cggaaauagc      180

aucuuccgaa ucgacacaga aggaacgaac uaugagcaac ucguagucga cgcaggggua      240

ucgguuauca uggacuucca uuacaacgag aaaagaauau acugggucga ccuagaacga      300

cagcuccugc aaaggguauu ccugaacggc ucgcggcagg aacggguaug caacauagag      360

aaaaacguca gcggcauggc cauaaacugg aucaacgaag aagugaucug guccaaccaa      420

caggaaggca ucauaaccgu cacugacaug aaaggaaaca acagccacau ccuccuauca      480

gcgcuaaagu accccgccaa ugucgcgguc gacccaguag aacgguucau uuucuggucc      540

uccgaaguag cugggagccu uuaccgcgca gaccuagacg gcgucggagu aaaagcacua      600

cuugaaacau ccgagaaaau aacagcagua ucccuugacg uccuagacaa gcgccucuuc      660

uggauacaau acaaucgcga agggucuaac agccucaucu gcaguuguga cuaugacggc      720

gggagcguac acaucucaaa acacccaaca caacauaauc uauucgcgau gagccucuuc      780

ggugacagaa uauucuacuc aaccuggaag augaaaacaa uauggauagc caacaaacac      840

acaggcaaag acaugguccg caucaaccuc cacagcuccu ucguaccccu cggcgaacua      900

aaaguagugc acccccuagc ccagcccaaa gccgaagaug auacguggga acccgaacaa      960

aagcugugca aacugcgcaa agggaacugc agcaguaccg uuugcgguca agacuuacag     1020

ucucaccucu gcaugugcgc ugagggguac gcccuuucga gagacagaaa auacugcgag     1080

gacgucaacg aaugcgccuu uuggaaccac ggcugcacac uuggcugcaa aaauacaccg     1140

ggaagcuacu acugcacaug ucccguagga uucguccuuc uacccgaugg aaagcgcugc     1200

caccaacugg ucucgugucc ucgcaacguc ucggaaugca gccaugacug cguacuaacc     1260

uccgaagguc cacuaugcuu cugcccagag gguucaguuc uagagcggga cggcaagaca     1320

ugcaguggau gcucaucccc agacaacggc ggaugcuccc aacuaugcgu cccacugagc     1380

ccggucucau gggaaugcga cugcuucccu ggguacgacc uccagcuuga ugaaaaauca     1440

ugcgcugccu ccgggcccca gcccuuccua cucuucgcca acucgcaaga cauaagacau     1500

augcacuucg acggcacaga uuacgggacc cugcuguccc aacagauggg caugguauac     1560

gcacucgacc acgacccagu ggaaaauaaa aucuauuucg cccacacagc ccuuaagugg     1620

aucgaacgcg ccaacaugga cggcagccaa agagaacggc ucauagaaga ggggguggac     1680

gugccagagg gccucgcugu cgacuggaua gggcgccggu ucuacuggac agaccggggc     1740

aaaagccuca uaggcagauc agaccucaac gggaaaagga gcaagaucau aacgaaagag     1800

aauaucucgc aaccccgcgg aaucgccguc cacccaaugg caaaaagacu auucuggaca     1860

gauacgggaa uaaacccccg gaucgagagc uccucccuac aagggcucgg gcgguuagua     1920

aucgccucca gcgaccuaau auggcccagc gggauuacca ucgacuuccu aacagacaaa     1980

cucuacuggu gcgacgcaaa acaauccguc aucgaaaugg ccaaucuaga cgguagcaaa     2040

cgacgccgac ucacacaaaa cgacguaggc caucccuuug cggucgccgu cuucgaggac     2100

uacgucuggu ucucugauug ggccaugccc ucagucaugc gagucaacaa gcgcacggga     2160

aaggaucgag ugaggcucca gggcucgaug uugaaaccaa gcagccuagu agucguccac     2220

ccacuggcaa aaccaggcgc agacccaugc cuauaccaga acgggggcug ugagcacauc     2280

uguaaaaaga gacuaggaac cgcauggugc ucaugcaggg aaggguucau gaaagcgucc     2340

gacggcaaaa ccugccuugc cuuagacgga caccaacucc uagcaggagg cgaaguugac     2400

cuuaaaaacc aaguaacgcc guuagauauc cucagcaaaa caaggguaag cgaggauaac     2460

aucaccgagu cacagcacau gcucguggca gaaauuaugg ugucagacca agacgacugc     2520

gcacccguag gcugcucuau guacgcaaga ugcauauccg aaggcgaaga cgccacaugc     2580

cagugccuga agggcuuugc cggggacggu aaacugugcu ccgacauaga ugagugcgaa     2640

augggaguac ccgucugucc gcccgcaagc uccaaaugca uaaacacaga aggcggauac     2700

gugugccggu gcucagaagg auaccaaggc gacggaaucc acugccugga caucgacgaa     2760

ugccaguuag gugaacauuc gugcggggaa aacgccuccu gcacuaacac cgaaggaggc     2820

uacacaugca ugugcgccgg acgucugagc gaacccgggc uaauaugccc cgacuccaca     2880

ccacccccac acuugcgcga ggacgaccac cauuacagcg uacggaacag cgacagcgaa     2940

ugcccccuau cacacgacgg cuacugcuua cacgacggcg ucugcaugua caucgaagcc     3000

cuagacaaau acgcgugcaa cugcguggua gguuacauag gugagcguug ccaauaccga     3060

gaccuuaaau ggugggaacu acgccacgcc ggacacggcc aacagcagaa ggucaucguc     3120

gucgcaguau gcgucguagu ccucgucaug cuucuacucc uaucacuaug gggcgcacac     3180

uacuacagaa cucaaaaauu auuaagcaag aaccccaaaa auccguacga ggaauccagc     3240

agagaugucc gcagccggag accggcggac acggaggacg gcauguccuc gugcccgcaa     3300

cccugguucg ucgucaucaa agaacaccaa gaccugaaga acggcggcca acccguagca     3360

ggagaagacg gacaagccgc cgacggaagc augcaaccga ccucguggcg acaagaaccc     3420

cagcuaugcg gcaugggcac ugagcagggc ugcuggauuc caguaaguag ugacaaaggu     3480

agcugcccac aggucaugga gcgauccuuc cauaugccuu cuuacggaac acaaacacua     3540

gaaggcggug uagaaaagcc gcauucucuc cuguccgcaa acccgcucug gcaacaacga     3600

gcacuagauc caccccacca aauggaacuc acccaauaag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  2348
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt11)

<400>  2348
gggagaaagc uuaccaugac cgccggccgc cgcauggaaa ugcucugcgc cggccgcguc       60

cccgcacucc uccucugccu cggcuuccac cuccuucaag ccguccucuc caccaccguc      120

auccccuccu gcauccccgg cgaauccucc gacaacugca ccgcccuagu ccaaaccgaa      180

gacaacccac gcgucgccca agucuccauc acaaaaugcu ccuccgacau gaacggcuac      240

ugccuccacg gccaaugcau cuaccucguc gacauguccc aaaacuacug ccgcugcgaa      300

gucggcuaca ccggcguccg cugcgaacac uucuuccuca ccguccacca accccucucc      360

aaagaauacg ucgcccucac cgucauccuc aucauccucu uccucaucac cgucgucggc      420

uccaccuacu acuucugccg cugguacaga aaccgcaaau ccaaagaacc caaaaaagaa      480

uacgaacgcg ucaccuccgg cgaccccgaa cucccccaag ucuaaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  2349
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt11)

<400>  2349
gggagaaagc uuaccauggc cgaaggcgaa aucaccaccu ucaccgcccu caccgaaaaa       60

uucaaccucc cccccggcaa cuacaaaaaa cccaaacucc ucuacugcuc caacggcggc      120

cacuuccucc gcauccuccc cgacggcacc gucgacggca cccgcgaccg cucagaccaa      180

cacauccaac uccaacucuc cgccgaaucc gucggcgaag uauacauaaa auccaccgaa      240

accggccaau accucgccau ggacaccgac ggccuccucu acggcuccca aacccccaac      300

gaagaaugcc ucuuccucga acgccucgaa gaaaaccacu acaacaccua caucuccaaa      360

aaacacgccg aaaaaaacug guucguaggc cucaaaaaaa acggcuccug caaaagaggc      420

ccccgcaccc acuacggcca aaaagccauc cucuuccucc cacuccccgu cucaucagac      480

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  2350
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt11)

<400>  2350
gggagaaagc uuaccauggu ggggguaggg ggaggggacg uggaggacgu aacgccgagg       60

ccgggagggu gucagauaag cgggagaggg gcgagagggu gcaacggaau accgggagcg      120

gcggcguggg aggcggcgcu gccgaggagg aggccgagga ggcacccgag cguaaaccca      180

agaagcagag cagcagggag cccgaggacg agggggagaa ggacggagga gaggccgagu      240

gggagcaggc ugggggaucg ggggaggggg agagcacugc cgggagggcg acuaggggga      300

agagggaggg ggagggcgcc ggagagggug ggagggaggg ggagggggag ggggacggcg      360

gcgccgagag cggcgccggc ggcgaggggg agcaggccgg gaccggcggg gacgauggca      420

gcggggagca uaaccacguu gccggcgcug ccggaagaug gagggagugg ggcguuccca      480

ccggggcacu ucaaggaucc gaagagacug uauuguaaga auggaggguu cuuucuaagg      540

auacauccgg augggagagu ggauggggug agggaaaaga gugacccgca cauaaagcug      600

caguugcagg cggaggagag agggguagua agcauaaagg gggugugcgc aaauagguau      660

cuggcgauga aggaggaugg gaggcuauug gcgagcaagu gugugacgga cgagugcuuu      720

uucuuugaaa ggcuagagag caauaacuac aacacguaca ggagcagaaa guauacgagc      780

ugguaugugg cgcugaagag aacgggacag uacaaguuag ggagcaagac agggccaggg      840

cagaaggcaa uauuguuccu gccaaugagu gcaaagagcu agggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  2351
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt11)

<400>  2351
gggagaaagc uuaccaugca caaauggauc cucaccugga uccuccccac ccuccucuac       60

cgcuccugcu uccacaucau cugccucguc ggcaccaucu cccucgccug caacgacaug      120

acccccgaac aaauggccac aaacgucaac ugcuccuccc ccgaacgcca cacccgcucc      180

uacgacuaca uggaaggcgg cgacauccgc guccgccgac ucuucugccg cacccaaugg      240

uaccuacgca ucgacaaacg cggcaaagua aaaggcaccc aagaaaugaa aaacaacuac      300

aacaucaugg aaauccgcac agucgccguc ggcauagucg caaucaaagg cgucgaaucc      360

gaauucuacc ucgccaugaa caaagaaggc aaacucuacg ccaaaaaaga augcaacgaa      420

gacugcaacu ucaaagaacu cauccucgaa aaccacuaca acaccuacgc cuccgccaaa      480

uggacccaca acggcggcga aauguucguc gcccucaacc aaaaaggcau ccccguccgc      540

ggcaaaaaaa ccaaaaaaga acaaaaaacc gcccacuucc uccccauggc caucaccuaa      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  2352
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt11)

<400>  2352
gggagaaagc uuaccaugaa acuccucccc uccguagucc ucaaacuauu ccucgcagcc       60

guccuauccg cccucgucac cggcgaauca cucgaacgcc uccgccgcgg ccucgccgca      120

ggcacaagca accccgaccc ccccaccguc uccaccgacc aacuccuccc ccuaggcggc      180

ggccgagacc gcaaaguccg cgaccuccaa gaagcagacc ucgaccuccu ccgcgucacc      240

cucuccucca aaccccaagc ccuagcaacc cccaacaaag aagaacacgg caaacgaaaa      300

aaaaaaggca aaggacuagg caaaaaacgc gaccccugcc uccgcaaaua caaagacuuc      360

ugcauccacg gcgaaugcaa auacgucaaa gaacuacgcg cccccuccug cauaugccac      420

cccggcuacc acggcgaacg augccacggc cuaucccucc ccguagaaaa ccgacuauac      480

accuacgacc acaccaccau ccucgccguc gucgccgucg uccucucauc cgucugccua      540

cucguaaucg uaggacuccu cauguuccgc uaccaccgcc gaggcggcua cgacgucgaa      600

aacgaagaaa aagucaaacu cggcaugacc aacucccacu aaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  2353
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt11)

<400>  2353
gggagaaagc uuaccaugug ggucacuaaa cuacuccccg cccuccuacu gcaacacguu       60

cuccuccacc uauuacugcu ccccauugca aucccauacg ccgaaggcca gcgaaaacgc      120

cgcaacacga uccacgaauu uaagaaaagc gcaaaaacaa cccuaaucaa aauagacccu      180

gcacuaaaaa uaaaaaccaa gaaagucaac acagcagacc aaugcgcuaa cagaugcacc      240

cggaacaaag gccugccguu cacaugcaag gcauucgucu ucgacaaggc ccgcaaacaa      300

ugccuguggu ucccauucaa cucaaugagc ucaggcguca agaaagaguu cggacacgag      360

uucgaccucu acgaaaacaa agacuacauc cgcaacugua ucaucggaaa aggaagaucc      420

uacaaaggca caguaucaau caccaagucc ggcaucaaau gccaacccug gagcagcaug      480

aucccccacg aacacuccuu ccuccccagc ucguaccgcg gcaaagaccu ccaagaaaac      540

uacugccgga acccccgagg agaagaaggc ggucccuggu gcuucaccuc caaccccgaa      600

guccgcuacg aagucugcga caucccccaa ugcagcgaag uagaaugcau gaccugcaac      660

ggcgaauccu acagaggccu aauggaucac accgaauccg gcaagauaug ccaacgcugg      720

gaccaucaaa ccccacaccg ccacaaguuc cuacccgaac gcuaccccga caaaggauuc      780

gacgacaacu acugccgcaa cccugacggg caaccacgcc ccuggugcua cacccuagac      840

ccacacacac gaugggaaua cugcgccauc aaaaccugcg ccgauaacac aaugaacgac      900

acugacgucc cacuagaaac caccgaaugc auacaaggac aaggcgaagg uuacagagga      960

accguaaaca cuauauggaa cggcauaccu ugccaacgcu gggacuccca auacccacac     1020

gaacacgaca ugacucccga aaacuucaaa ugcaaagacc uccgcgaaaa cuacugccgc     1080

aaucccgaug gguccgaaag ucccuggugc uucaccacag acccaaacau ccgcguggga     1140

uacugcuccc aaauucccaa cugcgacaug ucucacgguc aagacugcua ccgaggcaac     1200

ggcaagaacu acaugggaaa ccugucacag accagauccg gucuaaccug cuccaugugg     1260

gacaaaaaca uggaagaccu ccacaggcac auauucuggg aacccgacgc cuccaagcuc     1320

aaugaaaacu acugcaggaa ccccgacgac gacgcccacg gccccuggug uuacacagga     1380

aacccccuca uuccuuggga cuacugccca auaucacgcu gcgaagguga cacuacaccc     1440

acaauaguca accucgacca ccccgucauc ucuugcgcca aaacaaaaca acucagggua     1500

gucaacggaa uccccaccag gacaaacaua ggcuggaugg ucucccuacg guaccgcaac     1560

aaacacaucu gcggaggcuc acugaucaaa gaauccuggg uccucaccgc acgccaaugc     1620

uuccccagca gagaccucaa agacuacgaa gccugguuag guauucacga cguccacggc     1680

agaggggacg aaaaaugcaa gcaaguccuc aacguaagcc agcucgucua cggacccgaa     1740

ggaucggacc ucguacucau gaaacuggcc cgccccgcag uacucgacga cuucgucuca     1800

acgauugacc ugccaaacua cggaugcacg aucccagaaa agacgucaug uagcgucuac     1860

gguuggggcu acacgggccu caucaacuac gacggccucc uccgagucgc acaccuuuau     1920

aucaugggca acgaaaaaug cagccagcac caccgaggca aagucacacu uaacgaaucc     1980

gaaaucugug caggagccga gaaaauaggc ucaggacccu gcgaaggcga cuacggcgga     2040

ccccuggucu gcgaacaaca caaaaugcgc augguccuug gcgucaucgu acccggacga     2100

ggcugcgcca uccccaaccg ccccggcaua uucgucagag uugcauacua ugcaaaaugg     2160

auccauaaaa ucauacuaac auacaaaguc ccccagucau aaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  2354
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt11)

<400>  2354
gggagaaagc uuaccauggc aaaagcagca gcaauaggca ucgaccuagg aaccaccuac       60

ucaugcgucg gagucuucca gcacggcaaa guagaaauaa ucgcuaacga ccaaggaaac      120

agaaccacgc ccucguacgu cgccuucacc gacaccgaac gacugauagg ggacgcagca      180

aagaaccagg ucgcacucaa cccacaaaau acagucuucg acgcaaaaag acucauaggc      240

agaaaauucg gcgaccccgu agugcaaagc gacaugaaac acuggccauu ccaagugaua      300

aacgacgggg acaaaccaaa aguccaaguc ucauacaaag gcgaaacaaa ggcauucuac      360

ccagaagaaa ucuccagcau ggucuuaacc aaaaugaaag aaauagccga agcauaccuc      420

gguuacccag uaacgaacgc agucauuaca guacccgcau acuucaacga cagccaacgg      480

caagccacga aagacgcggg agucauagca gggcucaacg uauuaagaau aaucaacgaa      540

ccaacagcag cagccaucgc auacggccug gaucgcacag gcaagggcga aagaaacgua      600

cugaucuuug accuaggcgg gggcacguuc gacguaagca uccugaccau agacgacggg      660

auuuucgagg ucaaagcaac agcaggggac acacaccugg gcggggaaga cuucgacaac      720

agacucguga accacuucgu agaagaguuc aaacgcaaac acaagaaaga caucucgcag      780

aacaaaagag cagugagaag acuacggacc gcgugcgagc gcgcaaaacg cacccuaagc      840

ucaagcacgc aggcgagccu ggaaauagac agccucuucg aaggaaucga cuucuacaca      900

ucuauaacaa gagcgagauu cgaagaacug ugcuccgacc ucuuccgcuc cacgcuggag      960

ccagucgaaa aagcgcuccg ggaugcgaaa cuggacaaag cacaaaucca ugaccucgua     1020

cuggucggag gcucgacccg cauuccaaaa gugcaaaaac uccuccagga cuucuucaac     1080

ggacgagacc ucaacaaauc aaucaacccc gacgaagcag ucgcguacgg ggccgcuguc     1140

caagccgcaa uccugauggg ggacaaaagc gagaaugugc aagaccuccu ccuccucgac     1200

guggccccac ucucgcuugg acucgagacc gcgggaggcg uaaugacagc acucauaaaa     1260

agaaauucaa caaucccaac aaagcagaca cagaucuuca caacguauag cgacaaucaa     1320

ccgggcguac ucauacaagu auacgagggc gaacgcgcaa ugacgaagga caacaaccuu     1380

cuaggcagau ucgagcucuc aggcauacca ccagccccac gcgggguacc gcaaauagaa     1440

gugacauucg acaucgacgc aaacggaauc uuaaacguaa cagcgaccga uaaaucaacc     1500

ggaaaggcga acaaaaucac aaucacaaac gacaaaggac gccuuucaaa agaagagauc     1560

gagagaaugg uacaggaggc agaaaaguac aaagcagagg acgaggucca acgcgaaaga     1620

guauccgcca aaaacgcccu ggaaucauac gcauucaaca ugaaguccgc cgucgaagac     1680

gaaggucuaa agggaaagau auccgaagcc gacaaaaaga aaguacuaga uaaaugccaa     1740

gaagucauca gcuggcucga cgcaaacacc uuggccgaaa aagacgaauu ugaacacaaa     1800

agaaaagaac uugaacaagu augcaauccc auaaucucag gccuguacca aggcgcaggc     1860

gggccagggc ccgggggcuu uggggcacaa ggccccaaag gaggaagcgg aagcgggccg     1920

acaauagagg aaguagacua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2355
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt11)

<400>  2355
gggagaaagc uuaccauggc gaaagcagca gcaaucggaa ucgaccucgg uaccacauac       60

agcugcguag gcguauucca acacgggaaa guagaaauca uagcaaacga ccaagggaac      120

cggacaaccc ccuccuacgu cgccuucacc gacacagaac gacuuaucgg cgacgcagcc      180

aaaaaccagg ucgccuuaaa cccccaaaac accgucuucg acgcaaaaag acucaucgga      240

agaaaauucg gggaccccgu gguacaaagc gacaugaaac acuggcccuu ccaaguaauc      300

aacgacggag auaagcccaa gguccaagua ucguacaaag gcgagaccaa agccuucuac      360

ccagaagaaa uaucaagcau gguguuaacc aagaugaagg aaaucgccga agccuaccuc      420

ggcuacccag ugacaaacgc cguaauaacc gugcccgcgu acuucaauga cucccaacgc      480

caagccacga aagacgccgg cgucauagcc ggacuaaacg uacuacgcau aauaaaugaa      540

ccgacagcag ccgccaucgc auacggacuc gaccgcacag gcaaaggcga aagaaacgua      600

uugauauucg acuuaggcgg aggcaccuuc gacgucucga uacuaaccau agacgacgga      660

auauucgagg ucaaggccac cgccggagac acacaccuag gcggcgaaga cuucgauaau      720

cgucuaguga accacuucgu agaagaguuc aagcgcaaac acaagaaaga caucucccaa      780

aacaaacgug cagugcgaag gcuaagaacc gcaugcgaac gcgcaaaaag aacccucagc      840

uccagcacac aagcgagccu agaaauagac agucucuucg aaggcaucga uuucuacacc      900

ucgauaacua gagcgcgcuu cgaagaauua ugcagcgacu uauuccgauc gacauuagaa      960

ccuguagaaa aagcgcuccg ggacgcgaaa cuagacaaag cccaaaucca cgacuugguc     1020

cugguagggg gcucuacaag gauaccgaaa gugcaaaagc uauuacaaga cuucuucaac     1080

ggacgcgauc ucaauaaauc caucaacccc gacgaggcag uagcauacgg cgccgcgguc     1140

caggcagcga uacucauggg agacaaauca gaaaacgugc aagaccuccu gcuccuugac     1200

guagcaccac ucucgcucgg acuagaaacg gcgggagggg ucaugaccgc acucaucaag     1260

agaaacagua ccaucccaac caaacaaacc caaaucuuca ccacauacuc agacaaccaa     1320

ccgggagugc uaauccaagu auacgaaggc gaacgcgcga ugaccaaaga caauaaccug     1380

cuaggaagau ucgaacuauc aggcauaccc ccggcuccac gaggcguccc ccaaaucgaa     1440

guaaccuucg acauagacgc caacggaauc cucaacguga cagcgaccga caaaagcacc     1500

gggaaagcaa acaaaaucac aaucacaaac gacaaaggac gauuaagcaa agaagagauc     1560

gagcgaaugg uccaagaagc cgaaaaguac aaagccgaag acgaggucca acgcgaacga     1620

guaagcgcca aaaacgcauu agaauccuac gcguucaaua ugaaaagcgc aguagaagac     1680

gaaggacuga aagggaaaau aagcgaagca gacaaaaaga aaguacucga caaaugccaa     1740

gaaguaaucu ccuggcuaga cgcaaauacc cucgccgaaa aagacgaguu cgaacacaaa     1800

agaaaagaac uggaacaagu gugcaaccca auuaucucag gacuauacca gggggcaggc     1860

gggccaggac ccggaggauu cggcgcgcaa ggaccaaaag gaggcagcgg aagcggacca     1920

acaaucgagg aaguagacua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2356
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt11)

<400>  2356
gggagaaagc uuaccauggc gacagcaaag ggcauagcaa uaggcaucga ccucggcacc       60

acauacuccu gcguaggcgu cuuccaacac ggcaaaguag aaaucaucgc aaacgaccaa      120

ggaaacagga caacacccuc auacgucgca uuuaccgaca ccgaaagacu uaucggagac      180

gcggccaaaa accaggucgc aaugaacccc caaaauaccg ucuucgacgc aaagcgacuc      240

auaggacgca aauucaauga ccccguggua caggcagaca ugaaacuaug gccguuccaa      300

guuauaaacg aaggcggaaa gccgaaaguc cucguauccu acaaaggcga aaacaaagcc      360

uucuaccccg aggaaaucuc gagcaugguc cuaaccaaac ucaaagaaac agccgaagca      420

uuccucgggc acccagucac caacgcgguc auaaccguac cagcauacuu caacgacucg      480

caaagacagg caaccaaaga cgccggaguc aucgcaggac ugaacguccu ccgaaucauc      540

aacgaaccaa ccgccgcagc caucgccuac ggacuagaca aaggcgggca aggcgaacgg      600

cacguacuua ucuucgaccu cgggggcgga accuucgacg ucuccauccu gaccaucgac      660

gaugggauau ucgaagucaa agccacggcc ggagacacac accucggagg cgaagacuuc      720

gacaaccgcc uaguaaguca cuucgucgaa gaguucaaac gaaaacacaa aaaggacauc      780

agccagaaca aacgagcagu acgccgccuc aggacagcau gcgaacgcgc caaaaggaca      840

cuaagcuccu ccacgcaagc aaaccucgaa auagacagcc uauacgaagg aauagacuuc      900

uacacaagca ucacaagggc cagauucgaa gaacucugcg cagaccuauu ccggggcaca      960

cucgaaccag ucgaaaaagc gcugcgagac gccaagaugg acaaagccaa aauccaugac     1020

auaguccucg ucggaggcuc cacccgaauc cccaaaguac aacgacuucu acaggauuac     1080

uucaacggaa gagaucucaa uaaaucaauc aaccccgacg aggcggucgc auacggcgcc     1140

gccgugcagg ccgcaauacu caugggggac aaaagcgaga aaguacaaga ccuguuacua     1200

cuggaugugg caccccuaag ccucgggcug gaaaccgccg gaggggucau gaccgcccuc     1260

aucaaacgaa acuccacgau ccccacaaaa caaacccaaa uauucaccac cuacuccgac     1320

aaccagccag gaguacuaau ccaaguauac gaaggagaac gcgccaugac aaaagacaac     1380

aaccuacuag gccgguucga ucuaacaggc auaccaccgg cgccccgagg gguaccccaa     1440

aucgaaguaa cauucgacau cgacgccaac ggcauacuga acgugaccgc aacggacaaa     1500

ucgaccggga aagugaacaa aauaacaauc acaaacgaca agggccgcuu aagcaaggaa     1560

gaaaucgagc gcaugguccu agacgcagaa aaauacaaag ccgaagacga aguacaacga     1620

gagaaaaucg ccgcgaagaa cgcgcuggaa agcuacgcau ucaacaugaa aagcguagua     1680

ucagacgagg gacuaaaagg caaaauaagc gaaagcgaca aaaacaaaau acucgacaaa     1740

ugcaacgaac uacuaagcug gcuagaaguc aaucaacucg ccgaaaaaga ugaguucgac     1800

cacaaacgca aggaacucga acaaaugugc aacccaauaa ucaccaaacu uuaccaagga     1860

ggcugcacag gcccagcaug cggaacaggc uacguaccag gccgaccugc caccggcccc     1920

accauagaag aaguagacua gggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2357
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt11)

<400>  2357
gggagaaagc uuaccaugag ugcgcgcgga cccgcaaucg gaauagaccu cggcaccacc       60

uacucaugcg ugggcguauu ccagcacgga aaagucgaaa uaaucgcaaa cgaccaaggg      120

aacagaacca caccauccua uguggccuuu acugacaccg aacgccuaau cggagacgcu      180

gccaagaacc agguagcaau gaaccccaca aacacaaucu ucgacgcaaa gaggcuaauc      240

ggacgcaagu ucgaagacgc aacaguccaa agcgacauga agcacuggcc cuuccgcgua      300

guauccgaag gaggcaaacc caagguccaa gucgaauaca aaggcgagac aaagaccuuu      360

uucccagaag agaucucaag caugguacuc accaaaauga aagaaauagc ggaggcauau      420

cuuggaggaa agguccacag cgcagugaua acaguccccg cauacuuuaa cgacagccaa      480

agacaagcaa caaaagacgc aggaaccaua acaggacuua acguccuccg aauaaucaau      540

gaaccaacag cagcagcaau cgcauacggc cuagacaaga aaggcugcgc cggaggcgag      600

aaaaacgucc uaauauucga ccuaggcggg ggaacguucg acgucucaau acucaccaua      660

gaagacggca ucuucgaggu caaaagcacg gccggagaca cacaccucgg cggggaagac      720

uucgacaacc gcauggugag ccaucucgcc gaagaguuca aaagaaagca caagaaagau      780

auaggcccca acaaacgggc agugagaagg cucaggaccg caugcgaacg ggcgaaaaga      840

acccucagcu caagcacaca agcaaguauu gaaaucgacu cccuauacga agggguagac      900

uucuacaccu caaucacacg ggcccgcuuu gaggaacuaa acgccgaucu guuccgcgga      960

acacuagaac cagucgaaaa agcacuccga gacgcaaaau uagacaaagg ccaaauucaa     1020

gaaauagucc uggucggagg uuccacccgc aucccaaaaa uccaaaaacu acuacaagac     1080

uucuucaacg ggaaagaacu caacaaauca auuaaccccg augaagcagu cgccuacgga     1140

gcagcaguac aagcagcgau acucaucggg gacaaaagcg agaacgucca agaccuacua     1200

cugcuagacg ugaccccacu cucacucggg auagagacag caggcggagu aaugacccca     1260

cugauaaaac gaaacacaac cauacccaca aaacagaccc agaccuucac aaccuacagc     1320

gacaaccagu cauccguacu cguccaggug uacgagggag aacgagcaau gacgaaagac     1380

aacaaccuau ugggcaaguu cgaccuaacg ggcauaccgc ccgcgccccg cgguguacca     1440

caaaucgaag ucacuuuuga cauagacgcc aacggaaucc uaaacgugac cgcggccgac     1500

aaaagcacag ggaaggaaaa caagaucaca auaacaaacg acaaagggag acugagcaaa     1560

gacgacauug accgaauggu ccaagaagca gaacgcuaca aaucugaaga ugaggcaaac     1620

agagaccgag ucgcugcaaa gaacgcacug gaaucuuaca ccuacaacau caagcagacc     1680

gucgaagacg aaaaacugcg aggaaaaaua agcgaacaag acaaaaacaa aauacuggac     1740

aaaugucaag aagucauaaa cuggcucgac cgaaaccaaa uggccgaaaa agacgaauac     1800

gaacacaaac aaaaagaacu cgaacgagua ugcaacccca uaaucucaaa auuauaccaa     1860

ggaggcccag gaggcgggag cggcggagga ggcuccggag cgagcggagg ccccaccauc     1920

gaagaaguag auuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  2358
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt11)

<400>  2358
gggagaaagc uuaccauguc ggucguagga aucgaucugg gcuuucaauc augcuacguu       60

gcaguggcga gagcaggagg aaucgaaacc auagccaacg aauacagcga uagguguacg      120

ccggcaugca ucagcuucgg ccccaaaaac agaucaauag gagcagccgc caaaucacaa      180

gucaucucca acgcaaagaa caccguacaa ggcuucaagc gauuccaugg cagagccuuu      240

ucggacccgu ucgucgaagc ugaaaaaucc aacuuagcgu acgacauagu ucaacuccca      300

acaggauuaa ccggcaucaa agucaccuac auggaagagg agcgaaacuu uaccaccgaa      360

cagguaaccg cgaugcuccu aagcaagcua aaggaaaccg cagaaagcgu ccucaaaaag      420

cccgucguag auugcguggu cuccguccca ugcuucuaca cggacgcaga acgucgcagc      480

guaauggacg ccacacaaau agccggacuc aacugccuac ggcugaugaa cgaaacgacc      540

gcagucgcac uggccuacgg gauauauaag caagaccuac cagcgcugga agaaaaacca      600

cguaacgugg ucuucgucga caugggacac uccgccuacc aagucuccgu gugcgcguuc      660

aaccgcggca aacucaaagu ccucgcaaca gcguucgaua ccacauuggg cggacgcaag      720

uucgaugaag uacucguaaa ccacuucugc gaggaguucg gcaaaaagua caaacucgac      780

aucaaaucga aaauacgagc acuacuccgc cuuagccaag aaugugaaaa acuaaagaaa      840

cugaugucag caaacgccag cgaccuacca cuaucaauag aaugcuucau gaacgacgua      900

gacguaagcg gaacgaugaa ucgcggaaaa uuccuggaaa ugugcaacga ccuccucgcc      960

cgaguugagc cgccacuacg gagcgugcuc gaacaaacca agcucaagaa agaagacaua     1020

uacgccguag aaauagucgg gggcgcaacc cgcauccccg ccgugaaaga gaaaaucuca     1080

aaauucuucg ggaaagaacu cagcaccaca cucaacgccg acgaagcggu gacccgaggc     1140

ugcgcgcucc aaugcgcaau ccuaagcccc gccuucaaag uacgagaguu cuccauaacc     1200

gacguagucc ccuaucccau aucccuuagg uggaauagcc ccgcagaaga aggcagcagc     1260

gacugcgaag uauucagcaa aaaccacgcc gcacccuucu caaaaguacu gaccuucuac     1320

cgaaaagaac cauucacacu cgaggcauac uacagcuccc cacaggaccu cccauaccca     1380

gacccggcca ucgcccaauu cagcguacaa aaagucacac cacaaagcga cgguagcucg     1440

agcaaaguca agguaaaagu ccgggucaac guucacggca uauucucagu aagcagcgca     1500

agccucguag aaguacacaa auccgaggaa aacgaagaac ccauggaaac cgaccaaaac     1560

gccaaagaag aagagaaaau gcaaguagau caagaggaac cacacgucga ggaacaacag     1620

caacagaccc ccgccgaaaa caaagcagaa agcgaagaaa uggaaaccag ccaagccggc     1680

uccaaagaua agaaaaugga ccaaccacca caagccaaaa aggccaaagu caaaacaucc     1740

acagucgauc uccccauaga aaaccaacua cuauggcaaa ucgaccgcga gaugcucaac     1800

uuauacauag agaaugaagg caaaaugaua augcaagaca aacucgaaaa agagagaaac     1860

gacgccaaaa acgcagucga agaauacguc uacgaaaugc gagacaaacu aagcggcgaa     1920

uacgagaaau ucguaucgga agacgacaga aacagcuuca cccuaaagcu ggaggacacc     1980

gaaaacuggc uauacgaaga cggagaagac caacccaaac aaguauacgu agacaaacuc     2040

gcagaacuca aaaaccuagg ccaacccauc aaaauacgau uccaagaauc cgaggaacgc     2100

cccaaauuau ucgaagaacu cggcaagcaa auccaacagu acaugaaaau aauaucgagc     2160

uucaaaaaca aagaagacca auacgaucac cuggacgcag cagacaugac uaaaguagaa     2220

aaaucaacaa acgaagcaau ggaauggaug aacaacaaac ucaaccuuca aaacaagcaa     2280

agccuuacca uggacccagu agucaaaagc aaggaaaucg aagccaagau caaagagcuc     2340

acaucaaccu guuccccuau cauaucaaaa cccaaaccaa aaguagaacc acccaaggaa     2400

gaacagaaaa acgccgaaca aaacggcccc gucgacggac aaggcgacaa ccccggcccc     2460

caagccgccg aacaagggac cgacaccgca guaccaagcg acagcgauaa gaaacuuccc     2520

gaaauggaca ucgacuaggg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  2359
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt11)

<400>  2359
gggagaaagc uuaccauguc agucgucggc aucgaucucg gguuccugaa cugcuacaua       60

gcagucgccc ggaguggagg gaucgagaca auagcaaacg aauacucgga ccgcugcaca      120

cccgcaugca uaagccucgg cuccagaacg agagccaucg guaacgccgc uaagagccaa      180

aucguaacca acguacgcaa cacaauccac ggcuuuaaga aacuccacgg cagaucguuu      240

gacgacccua uaguccagac agagcgcaua cgacugcccu acgaacuaca gaaaaugcca      300

aacgggagcg cgggcgucaa aguccgauac cuagaagagg agcgcccauu cgcaauugaa      360

caaguaacug gaaugcugcu agcaaaauua aaagaaacga gcgaaaacgc ccuaaagaaa      420

cccguagccg auugcguuau cucaauaccg agcuuuuuca cagacgcaga gcggcgcuca      480

gucauggccg cagcccaagu cgccggccuc aacugccucc gccucaugaa cgaaacaacu      540

gccguugccc uggccuacgg caucuacaaa caagaccuac cgccccugga cgagaaaccg      600

cgaaacgucg ucuuuaucga caugggacac uccgcauacc aaguucuagu augcgccuuc      660

aacaaaggca agcucaaagu acuggcaacc acauucgacc ccuaccucgg uggacgaaac      720

uucgaugaag cgcucgucga cuacuucugc gacgaguuca aaacgaaaua caaaaucaac      780

gucaaggaga acucccgggc ccugcuaaga cucuaccaag agugcgaaaa acuaaagaaa      840

cuuaugucgg caaacgccuc agaccugccc cucaacauag aauguuucau gaaugaccuc      900

gacguaagcu ccaaaaugaa ccgcgcacaa uucgagcaac uaugcgccag ccugcuagcc      960

aggguagaac cuccacuaaa agcagucaug gagcaggcua accuacaacg cgaggacaua     1020

agcagcaucg agaucguggg aggcgccaca cgcauacccg cagucaaaga acaaaucacc     1080

aaauuuuucc uaaaagacau cucaaccacc cucaacgccg acgaagcagu agcgcgcggc     1140

ugcgcccucc aaugcgcgau acucagccca gccuucaagg uacgcgaguu caguaucacc     1200

gaccucgucc ccuacucaau aacacuaaga uggaaaaccu cguucgaaga cggcuccgga     1260

gaaugcgaag uauucugcaa gaaucacccg gcaccguucu cgaagguaau caccuuccac     1320

aagaaagaac ccuucgaacu ugaagcauuc uacacaaauc uucacgaggu accauacccg     1380

gacgcacgca uaggcucauu caccauccaa aacgucuucc cccaauccga cggcgacuca     1440

agcaaaguga aagugaaagu ccgcguaaau auccacggaa uauucuccgu agcaagcgca     1500

ucaguaaucg agaaacaaaa ccucgaaggc gaccacagcg acgcaccaau ggagaccgaa     1560

accagcuuca agaacgagaa caaggacaau auggacaaaa ugcaaguaga ccaggaagaa     1620

ggacaccaga aaugccacgc agaacacacc cccgaggaag aaaucgacca cacaggcgcc     1680

aaaacaaaau ccgccguaag cgacaaacag gaucgccuaa accagacgcu caaaaagggg     1740

aaagugaaau ccauagaccu acccauccag uccucacuuu gccgccagcu aggccaggac     1800

cuucugaacu cauacaucga aaacgagggg aaaaugauca ugcaagacaa acucgaaaag     1860

gaaaggaaug acgccaaaaa cgcagucgaa gaauacguau acgacuuccg cgaccgacug     1920

ggcacaguau acgaaaaauu cauuacaccc gaagaccuca guaagcuaag cgcggucuug     1980

gaggacaccg agaacuggcu cuacgaagac ggcgaggacc agcccaaaca aguauacgug     2040

gacaaacuac aagaacucaa aaaguacgga caaccuaucc aaaugaagua cauggaacac     2100

gaagaacgcc caaaagcucu aaacgaccua ggcaagaaga uacagcucgu aaugaagguc     2160

aucgaagccu accgcaacaa agacgaaaga uacgaccacc uagacccaac cgaaauggaa     2220

aaaguagaaa aaugcauaag cgaugcaaug agcuggcuca acucuaagau gaaugcacaa     2280

aacaaacucu cccuuaccca agacccaguc guaaaagucu cagaaauugu cgcgaaaagc     2340

aaagagcuag acaacuucug caaucccauc aucuacaagc ccaaacccaa agcagaagua     2400

cccgaagaca aacccaaagc caacuccgaa cacaacggcc cgauggacgg ccaaagcgga     2460

accgaaacaa aguccgacag uaccaaagac agcucgcagc acaccaaguc cuccggcgaa     2520

auggaagucg acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  2360
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt11)

<400>  2360
gggagaaagc uuaccaugaa acuaagccug gucgcagcaa ugcugcuacu acuaagcgca       60

gcaagggcag aggaagaaga caagaaagag gacgucggca caguagucgg aauagaccug      120

gggacgaccu acagcugugu aggggucuuc aagaacggca gaguugaaau caucgcaaac      180

gaccaaggca accgaauaac accgagcuac guagcguuca cacccgaagg cgaaagacuc      240

aucggggacg cagccaaaaa ccaacuaaca agcaacccgg aaaacacagu guucgacgcc      300

aaaagacuaa ucggcagaac cuggaacgac cccuccgucc aacaagacau aaaauuccuc      360

ccauucaaag ugguagaaaa gaaaacgaaa cccuacauac aagucgacau agggggcggg      420

cagacaaaaa cauucgcgcc agaagaaauc agcgcaaugg uccuaaccaa aaugaaagaa      480

acggcagaag cguaccuggg aaagaaaguc acccacgccg ucgucacggu ccccgccuac      540

uucaacgacg cgcaacgaca agcaaccaaa gacgcaggca cgaucgcggg acugaacgua      600

augaggauaa ucaacgaacc aacagcagcc gccaucgcau acggacugga caagcgcgaa      660

ggagagaaaa acauacuggu cuucgaccug ggcggaggaa cauucgacgu cucgcuacug      720

acaauagaca acggcguauu cgaggucgug gcuacgaacg gagacacaca ccuaggaggg      780

gaagacuucg accaacgagu cauggaacac uucauaaaac uauacaagaa gaaaaccgga      840

aaagacguaa gaaaagacaa cagagccgua caaaaacuga ggcgcgaagu agaaaaagcg      900

aaacgggccc ugagcucgca acaccaagcg agaauagaaa uagaguccuu cuacgaagga      960

gaagacuuca gcgaaacacu aacgcgcgcc aaauucgaag aacucaacau ggaccucuuc     1020

cgcucaacua ugaagcccgu ccaaaaagug cucgaagaca gcgaccugaa aaagagcgau     1080

aucgacgaaa uaguacuggu aggcggaagc acacggaucc caaaaauaca gcaacucgug     1140

aaagaguucu ucaacggaaa agaaccaucg cgagggauca acccagauga agcggucgca     1200

uacggugcag cgguccaggc cgggguacua agcggagacc aagacacagg agaucuggua     1260

cuccuugacg ugugcccacu aacccucggg auagagaccg uaggcggcgu uaugacaaaa     1320

cugauccccc gcaacaccgu aguacccacg aagaaaagcc aaaucuucag cacggcaagc     1380

gacaaccaac cgaccguaac cauaaaagug uaugaggggg aacgaccccu cacgaaagac     1440

aaccaccuac ucggcacauu cgaccucaca ggaauaccac cagccccgcg cggaguacca     1500

caaaucgaag uaacguucga aaucgacgug aacggaaucc uacgcgucac cgccgaggac     1560

aaagggaccg gcaacaagaa caaaaucacc aucacgaacg accaaaaccg ccucacaccg     1620

gaggaaaucg aacguauggu caacgacgcg gaaaaguucg cggaagagga caagaaacuc     1680

aaagaacgca uagacacgcg aaacgaacug gaaucauacg cauacucacu gaaaaaccaa     1740

auaggagaca aggaaaagcu aggaggcaag cuaucgagcg aggacaaaga aacaauggaa     1800

aaggcagucg aggagaaaau agaauggcua gaaucccacc aagacgcaga cauagaagac     1860

uucaaagcga aaaagaaaga guuagaagaa aucguucaac caaucaucag caaacuauac     1920

gguagcgcag gcccaccgcc uacaggcgag gaagauaccg cagaaaaaga cgagcuguag     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  2361
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt11)

<400>  2361
gggagaaagc uuaccaugca agccccacga gagcuagcag uaggaauaga ccucggaacu       60

acauacucau gcguaggcgu auuccaacaa ggacgcguag aaauacucgc aaacgaccaa      120

ggcaaccgca ccacgccaag cuacgucgcc uuuaccgaca ccgagagacu cguaggcgac      180

gcagccaaau cgcaggccgc ccucaauccc cacaacaccg ucuucgacgc gaaaagacua      240

aucggccgaa aauucgccga uaccacaguc caaagcgaca ugaaacacug gcccuuucgc      300

guagugucag aaggaggaaa accaaaaguc agggucugcu accgaggaga agacaaaacc      360

uucuacccag aagagauauc gaguauggua cuauccaaaa ugaaggaaac cgcagaagcc      420

uaccuaggac aaccaguaaa gcacgccguc auaacaguac cagcguacuu caacgacagc      480

caaagacaag ccaccaagga cgccggggcc auagccggac uaaacguccu ccgcauaauc      540

aacgaaccga ccgcugccgc gaucgcauac ggccucgacc gcaggggagc uggcgaaaga      600

aacguccuca ucuucgaccu cggaggggga acauucgacg ucucaguacu aaguauagac      660

gccggcguau uugaaguaaa agccacagca ggcgacaccc accuaggagg agaagacuuc      720

gacaaccgac ucgugaacca cuucauggaa gaguuccgac gcaaacacgg caaagaccuc      780

uccggcaaca aacgggccuu gagacgacuc agaacagccu gcgaaagagc aaaaagaaca      840

cucagcucaa gcacacaagc gacauuagaa auagacuccc uauucgaggg cguagacuuc      900

uauaccucga ucacacgcgc aagauucgag gaacugugcu cagaccucuu cagaucaacc      960

cucgaaccgg ucgagaaagc ucuaagagac gccaaacuag acaaagcaca aauccacgac     1020

gucgucuuag uaggcggaag cacccgaaua ccaaaagugc aaaaacuccu acaagacuuc     1080

uucaacggaa aggagcucaa caagucaaua aaccccgacg aagccgucgc auacggggcc     1140

gcaguacagg ccgcagugcu caugggcgau aaaugcgaga aaguccaaga ccuucuacua     1200

cucgacguag ccccacuuuc ccuagggcuc gaaaccgcgg gcgggguaau gaccacccuc     1260

auccaacgaa acgcaacaau accaacuaaa caaacccaga ccuucacaac auacucagac     1320

aaucaaccgg gaguauucau acaagucuac gaaggcgaac gagccaugac aaaagacaac     1380

aaccuucucg gcagguuuga acucagcggc auacccccag ccccacgcgg cgucccacaa     1440

auagaaguca ccuucgauau agacgccaac ggcauacuca gcguaacggc aaccgaccgc     1500

agcaccggaa aagcgaacaa gauaaccauc acaaacgaca aagggcgccu aagcaaagaa     1560

gaggucgagc gcauggucca ugaagcagaa caguauaaag cagaggacga agcccaacga     1620

gacagaguag cagcgaaaaa cagucucgag gcacacgugu uccacgucaa aggcucacua     1680

caagaagaga gccuacgaga caaaaucccc gaagaagaca ggcggaaaau gcaagauaaa     1740

ugccgcgaag uacucgcuug gcucgagcac aaccaacugg ccgaaaagga ggaauacgaa     1800

caccaaaaac gagaacucga gcagauaugc cgacccauau ucucccgccu cuacggcggc     1860

cccggcgucc ccggaggaag cagcugcggc acgcaagcca gacaaggaga ccccucaacc     1920

ggacccauaa ucgaagaagu ggacuaagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  2362
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt11)

<400>  2362
gggagaaagc uuaccaugca agccccccgc gaacuagccg uaggcaucga ccucggcaca       60

accuacagcu gugucggcgu auuccaacaa ggcagaguag aaauccuagc caacgaccaa      120

ggcaacagaa cgaccccauc auacgucgcg uucaccgaca cagaaaggcu aguaggagac      180

gcagcaaaau cccaagcagc ccuaaacccg cacaacacug uauucgacgc caaacgccua      240

aucggacgaa aauucgcaga cacaaccguc caaucagaca ugaaacacug gccauuccaa      300

gucgucuccg aagguggaaa acccaaagua cgaguaugcu accgagggga agacaaaaca      360

uucuacccag aagaaauaag cucaauggua cuaagcaaaa ugaaagaaac cgcggaagcc      420

uaccuaggcc aaccaguaaa acacgccgua aucacggucc cgaccuacuu cagcaacucc      480

cagagacagg ccaccaaaga cgcaggagca aucgcaggcc uaaaaguacu cccaaucaua      540

aacgaagcca cagccgcagc aauagccuac ggccuggacc gaagaggagc cggcaaacga      600

aacguacuca uauucgaccu aggaggagga acauucgacg uauccguacu cucgaucgac      660

gccggggucu ucgaaguaaa agcuaccgcc ggcgacaccc accuaggagg cgaagacuuc      720

gacaaccgcc uagucaacca cuucauggaa gaauuccgca gaaaacacgg caaagaccua      780

agcggaaaca aacgagcccu cagacgacuc cgaacagccu gcgaacgagc caaacgcacc      840

ccaucaagca gcacccaggc cacacuagaa aucgacuccc uauucgaagg cguagacuuc      900

uacaaaagca ucaccagagc cagauucgaa gaacucugca gcgaccuauu ccgaagcacc      960

cuagaacccg uggaaaaagc ccuccgcgac gccaaacuag acaaagcaca aauccacgac     1020

uucguacuag gcggcgggcu ccacagccac ccacaaggcg cagaagucgc cgcaggccua     1080

cuccaacgac aaggcgcaga acaagaacac cagccauaag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  2363
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt11)

<400>  2363
gggagaaagc uuaccauguc aaaaggaccc gcagugggaa ucgaccuagg caccaccuac       60

ucaugcguag gcgucuucca acacggaaaa gucgagauaa ucgccaacga ccaaggaaac      120

aggacgacac caucauaugu agccuucacc gacaccgagc gccuaauagg agacgccgcc      180

aaaaaccagg ucgcaaugaa cccaacgaac accguauucg acgccaaacg acuaaucggc      240

cgccgauucg acgaugcagu cguccagagc gacaugaaac acuggcccuu caugguagua      300

aacgacgccg gccgaccaaa gguacaaguc gaauacaaag gcgaaaccaa auccuucuac      360

cccgaagagg uguccagcau gguccucacc aaaaugaaag aaauagcaga agcguaccug      420

gggaaaacag ucaccaacgc aguagucacc guccccgcau acuucaacga cagccagaga      480

caagcaacaa aagacgcagg caccaucgcc gggcuaaacg uccuacgcau aaucaacgaa      540

cccacagcag cugcaaucgc auacggucuc gacaagaaag uuggugccga acgcaacguc      600

cuaaucuucg accucggggg cggcaccuuc gacguaucaa uccucacaau agaagacgga      660

auauucgaag ucaaaagcac cgcaggcgac acccaccuag gcggcgagga cuucgacaac      720

agaaugguaa accacuucau cgcagaguuc aaacggaaac acaagaaaga caucuccgaa      780

aacaaacgcg caguacgacg ccuacggaca gcaugcgaac gcgccaaacg cacccucucc      840

uccuccaccc aagcaagcau agaaaucgac agccuauacg aaggaauaga uuucuacaca      900

uccaucacaa gggcgcgcuu cgaagaacua aacgcagacc ucuuccgagg uacccucgac      960

ccagucgaaa aagcauuaag agacgcaaaa cuagacaaaa gccaaaucca cgacauaguc     1020

cuggugggcg gaucaacccg uaucccuaaa auccaaaaac uacuacagga cuucuucaac     1080

ggaaaagaac uaaacaaguc caucaaccca gacgaagcug uggcauacgg cgcggccgua     1140

caagccgcca uccuaagcgg cgacaaaucg gaaaacgugc aggaccugcu acuccuagac     1200

gucacacccc ucucacuagg cauagaaacc gcgggcggcg uaaugaccgu ccuaauaaaa     1260

cgaaacacaa ccauaccaac caaacaaacg caaaccuuca caacauacag cgacaaccaa     1320

ccagggguac ucauccaagu auacgaaggc gaacgcgcaa ugaccaaaga caacaaccuc     1380

cuaggcaaau ucgaacuuac aggaauccca cccgcacccc gagggguacc ccaaauagaa     1440

guaacauuug acauagacgc caacggcauc cuaaauguca gcgccgucga caaaagcacc     1500

ggaaaagaaa acaaaauaac gauaaccaac gacaaaggcc gacugagcaa agaagacauc     1560

gagcgaaugg uacaagaagc cgaaaaauac aaagcagagg augaaaaaca gcgcgacaaa     1620

guaucaagca aaaacagucu ggaaagcuac gccuucaaca ugaaagcaac aguggaagac     1680

gaaaaacucc aaggcaagau caaugacgaa gacaagcaga aaauccucga caaaugcaac     1740

gaaaucauca acuggcucga caagaaccaa acagcagaaa aggaagaguu cgaacaccaa     1800

cagaaagaac ucgaaaaagu cugcaacccc auaaucacaa aacuguacca auccgcaggc     1860

ggaaugcccg gcggcaugcc cggaggauuc ccaggcggcg gggcaccacc caguggcgga     1920

gccagcucag gaccgacaau cgaagaagua gacuaaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  2364
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt11)

<400>  2364
gggagaaagc uuaccaugau aagcgccuca agagcagcag ccgccagacu gguaggagcc       60

gcagcaucaa ggggcccgac agcagccaga caccaagacu cauggaacgg ccuaagccau      120

gaagcauucc gccucguaag ccgacgcgac uacgcgagcg aagcaauaaa aggagccgug      180

gucggcauag accuaggaac cacgaacucg ugcguggccg uaauggaggg aaaacaagca      240

aaaguacucg aaaacgccga aggggcaaga acaacgcccu caguaguagc guucacugcg      300

gacggcgaaa ggcuaguagg caugccagca aaacgacaag cggugacaaa cccaaacaac      360

acguucuacg caacaaaacg acucauagga cgacgauacg acgacccgga aguacaaaaa      420

gacaucaaaa acgucccguu caaaauagug cgcgccagua acggagacgc cugggucgaa      480

gcccacggca aacucuacag cccaucccag aucggcgccu ucguccuaau gaagaugaaa      540

gagaccgccg aaaacuaccu cggacacaca gcuaaaaacg cagucaucac ugugccagcg      600

uauuucaacg acagccaaag gcaagccacg aaagacgccg ggcaaauaag uggacuaaac      660

guccuaaggg ucaucaacga accgacugca gcggcccugg cauacggccu agacaagagc      720

gaagacaaag uaauagccgu auacgaccua ggaggcggga cauucgacau aagcauccua      780

gaaauacaga aaggaguauu cgagguaaaa agcacgaaug gggacacguu ccuggguggc      840

gaagacuucg accaagcacu gcuacgccac aucgugaagg aguucaaacg agaaacaggg      900

gucgaccuca caaaagacaa cauggcgcuc caacgagucc gcgaagcagc ggaaaaagca      960

aaaugcgaac uaagcagcag cguacaaacc gacauaaacc uacccuaccu aacaauggac     1020

aguagcgggc caaaacaucu caacaugaaa uuaacaagag cucaauucga aggcaucgua     1080

acggaccuaa uacgacgaac caucgccccg ugccaaaaag ccaugcaaga cgcagaagua     1140

agcaagagcg acauaggaga aguaauacug guaggcggca ugacaagaau gccgaaagua     1200

caacaaaccg uacaagaccu auucggacga gcaccaagca aagccgucaa cccggaugaa     1260

gcaguggcca uuggcgcagc aauccaggga ggcgugcuag cgggcgaugu aacagacgua     1320

cuccuacuag acguaacccc gcuaagccua ggaauagaaa cccuaggcgg aguauucaca     1380

aagcugauaa acagaaacac aacaauccca accaagaaaa gccaaguauu cagcaccgcg     1440

gcagacgggc aaacccaagu ggagaucaaa gucugucaag gagaacgaga gauggccggc     1500

gauaacaaac ugcucggcca auucacccug aucggcauac cacccgcgcc gagaggagua     1560

ccccaaaucg aggucacguu cgauaucgac gccaacggca uaguccaugu aagcgccaaa     1620

gacaaaggaa ccggacgcga acaacaaaua gucauccaau caagcggagg ccuaagcaaa     1680

gacgacaucg agaacauggu caaaaacgcg gaaaaauacg cagaggaaga ccgaagaaag     1740

aaagaaagag ucgaagcagu aaacauggcc gaaggaauaa uacacgacac cgaaaccaaa     1800

auggaagagu ucaaagacca acuaccagcu gacgaaugca acaaacucaa agaagaaaua     1860

aguaaaaugc gagagcuacu agcgcgcaaa gacagcgaaa cgggagaaaa uauacgccag     1920

gcagcgagca gccugcaaca agcuagccua aaacuguucg aaauggccua caagaaaaug     1980

gcauccgaaa gggaaggaag cggaagcagc ggcaccggcg aacagaaaga agaccaaaaa     2040

gaagagaaac aguaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  2365
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt11)

<400>  2365
gggagaaagc uuaccauggc agauaaagaa gcaggcggau ccgacgggcc acgagaaacc       60

gccccaacau ccgcauacag cucgccagcc cgaucacuag gagacaccgg uauaacgccc      120

cuuucccccu cccacaucgu caacgacacc gacucaaacg uauccgaaca acaauccuuc      180

uuaguugucg uggccgucga cuucggaaca acaucauccg gcuaugccua uucauucacc      240

aaagaaccgg agugcaucca cgucaugcgu cgcugggaag gaggagaccc cgggguuuca      300

aaccagaaaa cccccaccac cauccuucuc acccccgaac ggaaauucca cuccuucggc      360

uacgccgccc gggacuucua ccacgaucua gacccgaacg aagcaaagca auggcucuac      420

cuagaaaaau ucaaaaugaa acuucacacc accggcgacc ucacaaugga uacagaccuu      480

acagccgcaa acggcaagaa agucaaagcg cucgaaaucu ucgccuacgc acuccaauac      540

uucaaagaac aagcccucaa agagcuaucc gaccaagccg gcucagaguu cgaaaacuca      600

gacguccgcu gggucauaac aguaccugcg auauggaaac aacccgccaa acaguuuaug      660

agacaagcag ccuaccaggc uggacuggca uccccugaaa acucagaaca acucauaauc      720

gcgcuagaac ccgaagcugc aagcauauac ugccgaaaac uccgccucca ccagaugauc      780

gaacugagcu ccaaagcagc cguaaacgga uacagcggcu ccgacacugu cggcgcagga      840

uucacccaag cuaaagaaca cauccgacga aaccgccagu cacgcacuuu ccuagucgaa      900

aacgucauag gagaaaucug gagcgaacua gaagaaggag acaaauacgu cguggucgau      960

ucaggcggcg gcaccgucga ccuaacaguc caccaaauca ggcuaccaga gggccaccuc     1020

aaagagcuau acaaagcaac cggcggcccc uacggauccc ucgguguaga cuaugaguuc     1080

gagaaacugc ucuacaaaau auuuggcgag gacuuuaucg agcaauucaa aaucaaacgc     1140

cccgccgccu gggucgacuu gaugaucgcc uucgaaagcc gaaaacgcgc cgccgccccc     1200

gacagaacaa acccacuaaa caucaccuua cccuucucgu ucaucgacua cuacaagaaa     1260

uuucgcggcc acuccgucga gcacgcccua cgaaaaagca acgucgacuu cgucaaaugg     1320

ucaucgcaag gaaugcuccg uauguccccc gacgccauga augcccuauu caaacccaca     1380

auagacucca ucaucgaaca ccuccgcgac cucuuucaaa agccagaagu aucaaccguc     1440

aaauuucucu uccuagucgg cggcuucgca gaagcacccc uacuccaaca agccguucaa     1500

gccgcuuucg gcgaccaaug cagaaucaua aucccacaag acguaggacu caccauucuc     1560

aaaggcgccg uacuuuucgg ccucgaccca gccgucauua aagugcgaag auccccucug     1620

acauacggcg ucggaguccu aaaccgcuac gucgaaggaa aacacccacc cgaaaaacuu     1680

cuagucaaag acggcacccg auggugcacc gacguauucg auaaauucau aucagcagac     1740

caaagcgucg cccucggcga gcuagucaaa agauccuaca cacccgccaa accaagccaa     1800

cucgucaucg uuaucaacau auacuccagc gaacacgaca acguaucguu cauaaccgac     1860

cccgggguaa agaaaugcgg cacccuccgc cucgaccuaa caggcaccuc aggcaccgcc     1920

gucccagcac gcagagaaau acaaacccuc augcaguucg gugacaccga aaucaaagcc     1980

accgccaucg acauagcaac caguaaaucg gucaaaguag gcauagacuu ucuaaacuac     2040

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  2366
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt11)

<400>  2366
gggagaaagc uuaccaugcu agccguccca gaaaugggcu uacaaggacu uuacaucgga       60

agcuccccag aacgaucacc cguacccagc ccacccggau caccccgcac ccaggaauca      120

ugcggaaucg cgccccugac acccagccaa agcccaaaac ccgaaguacg ggccccgcaa      180

caagccuccu ucagcguagu cguggccaua gacuucggaa cgaccagcag uggcuacgca      240

uucucauucg caagcgaucc agaggccaua cacaugaugc gaaaauggga aggcggcgac      300

ccaggaguag cacaccagaa aaccccaaca ugccuacucc uaacccccga aggcgccuuc      360

cacucauucg gcuacacugc aagagauuac uaccacgacc ucgacccgga agaagcccgc      420

gacuggcucu acuucgagaa auucaagaug aaaauccaca gcgccacaga ccuaacacug      480

aaaacccaac ucgaggcggu gaacggcaag acaaugccag cacucgaagu auucgcacac      540

gcccuccgau ucuuccgcga acacgcacua caagaacuac gcgaacaaag ccccagucug      600

cccgagaagg acaccguccg guggguguua accguacccg caaucuggaa acaaccagca      660

aaacaauuca ugcgcgaagc cgccuacuua gccggacuug uaagcagaga gaacgcagaa      720

caacuccuca uagcccugga acccgaagcc gccuccguau acugccgaaa acuacgacua      780

caccaacuac uagaccuguc gggccgcgcc cccggcggcg gccgccuagg cgaaagacga      840

agcauagacu ccuccuuccg ccaagcccga gaacaacuaa gaagauccag acacucacga      900

accuuccuag uagaauccgg agucggagaa cuaugggccg aaaugcaagc cggcgaccgc      960

uacguagucg ccgacugcgg agggggcacu gucgaccuua ccguacacca acuagaacaa     1020

ccacauggca cccuaaaaga acuauacaaa gccucgggag gucccuacgg ggcugucggc     1080

guagaccucg cauucgagca acuccuaugc cgcaucuucg gagaagacuu caucgcaaca     1140

uucaaacgcc aaaggcccgc cgcauggguc gaccucacua ucgccuucga agcacgaaaa     1200

cgaacagcag gaccccaucg cgcaggcgcc cucaacaucu cacuacccuu uuccuucaua     1260

gacuuuuaca gaaaacaaag agggcacaac guagagacag cacucagacg auccagcgug     1320

aacuucguaa aauggucauc ccaagggaug cugcgaaugu caugcgaagc aaugaacgag     1380

cuauuccaac caacaguauc aggcauaauc caacacaucg aagcacugcu cgcccgacca     1440

gaaguacaag gcguaaagcu ccucuuccua gucggcggau ucgccgaaag cgcaguccuc     1500

caacaugccg uccaagccgc ccugggcgca cgcggacuac gagucgucgu accacacgac     1560

gucggacuca cgauacucaa aggagccgua cuauucggac aagccccagg aguaguccgc     1620

guccgccguu cgccgcucac cuacggcguc ggcguccuca acagauucgu accaggacgc     1680

caucccccag aaaaacugcu gguccgcgac ggccgcagau gguguacaga cgucuucgaa     1740

cgcuucguag cagccgagca auccgucgcg cuaggagagg aaguccgccg uucauacugu     1800

cccgccagac ccggccaacg aagaguacuc aucaaccuau acugcugcgc agcagaagac     1860

gcacgcuuca uaacugaccc aggcguccgg aaaugcggcg cccucucacu agaacucgaa     1920

cccgccgacu gcggacagga caccgcagga gccccacccg gacgacgcga aauucgggcc     1980

gccaugcaau ucggcgacac cgaaaucaag gugacagccg uggacgucag cacgaaccgc     2040

agcguuagag caagcauaga cuuccucuca aacuaaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  2367
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt11)

<400>  2367
gggagaaagc uuaccauggc ccgcgaaaug accauccucg gcucagccgu ccuuacccua       60

cuacuagcgg gauaccuagc ccaacaauac cuuccacuac ccacccccaa agucauaggu      120

auagaccucg gaaccaccua cugcuccguc ggcgucuucu uucccggaac cggaaaaguc      180

aaagucaucc cagacgaaaa cggacacauc ucuauccccu cgauggucag cuucacagac      240

aacgacguau acgucggcua cgaauccguc gagcuagccg acagcaaccc acaaaacaca      300

aucuacgacg ccaaacgcuu caucggcaaa aucuucaccg ccgaagaacu cgaagccgaa      360

aucggacgcu accccuucaa aguacucaac aaaaacggca uggucgaguu cucaguaacc      420

agcaacgaaa ccauaaccgu aucccccgaa uacgucggcu cacgcuuacu acuaaaacuc      480

aaagagaugg cagaggcuua ccucggcaug ccggucgcca acgcugucau aagcgucccc      540

gcggaguucg accucaaaca acgcaacucc accauugaag cagcgaaccu ggcaggacua      600

aaaauccucc ggguaauaaa cgaacccaca gcagcagcca uggccuacgg acuccauaaa      660

gccgacgucu uucacguucu agucaucgac uuaggcggag gcacccucga cgucucccuc      720

cucaacaaac agggcggaau guuccuaaca cgcgccaugu caggcaacaa caaacucggc      780

ggccaggacu ucaaccaacg ccuacuucaa uaccucuaca aacagaucua ccagaccuau      840

ggauucguac ccucucggaa agaagaaauc caccgccucc gccaagccgu agaaaugguu      900

aaacucaacc ucacccuaca ccagucagcg caacuauccg uccuccucac ggucgaagaa      960

caagaccgca aagaacccca cucaucagac accgaacucc ccaaagacaa acucuccuca     1020

gccgacgacc accgcgugaa cucaggcuuc ggccgcggcc uauccgacaa gaaauccggc     1080

gaaucucaag uacucuucga gacagaaaua agccgcaaac ucuucgacac ccuaaacgaa     1140

gaccucuucc agaaaauacu cguacccauc caacaagucc uaaaagaagg ccaccuugag     1200

aaaaccgaaa ucgacgaagu cguucucguc ggcggcucca cccgcauccc ccguauucga     1260

caagucauac aagaauuuuu cggaaaagau cccaacacua gcgucgaccc cgaccuugca     1320

guagucacag ggguagccau ccaagccgga auagacggcg gauccuggcc ccuucaaguc     1380

uccgcacucg aaauccccaa caaacaccuu cagaaaacca acuucaacua gggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2368
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt11)

<400>  2368
gggagaaagc uuaccauggc cgccaucgga guccaccucg gcugcacauc cgccugcgug       60

gccgucuaca aagacggacg cgcaggcgua gucgccaacg acgccggaga ccgcgucacc      120

cccgccguag ucgccuacag cgaaaacgag gaaauagucg gacucgccgc caaacaaucc      180

cgaauacgca acauauccaa cacaguaaug aaagucaaac aaauccucgg acgaagcagc      240

agcgacccac aagcccaaaa auacaucgcc gaauccaaau gccuugucau cgagaaaaac      300

ggaaaacuac gauacgaaau cgacacaggg gaagaaacca aguucgucaa cccagaggac      360

gucgcacgcc ucaucuucag caaaaugaag gagaccgcac auagcguacu aggguccgac      420

gccaacgacg ucguaauaac cgucccauuu gacuucggcg aaaaacaaaa gaacgcacua      480

ggcgaagccg cccgcgccgc uggcuucaac guccugcgac uaauacacga accaucagca      540

gcacuacuag ccuacggcau cggacaagac ucaccaacag gcaaaucaaa cauacucgua      600

uucaaacucg gaggcacuag ccuaucacua uccguaaugg aggugaacag cggcaucuac      660

cgcguacuca guaccaacac agaugacaac auaggcggcg cccacuucac agaaacccua      720

gcgcaauacc uagcgucgga auuucaacgc agcuucaaac acgacgucag aggaaacgcc      780

cgcgcgauga ugaaacuaac caacagcgcg gaagucgcaa aacacucccu cucaacccuc      840

ggcuccgcca acugcuuccu cgacucacuc uacgaaggcc aggacuucga cugcaacguc      900

ucaagagccc gcuucgaacu ccugugcucc ccacuauuua acaaauguau cgaagcaaua      960

cgcggacucc uagaccaaaa cggcuucaca gccgacgaca ucaacaaagu cguccucugc     1020

ggcggcagcu cgcgcauccc caaacuccaa caacuaauca aagaccucuu cccagccguc     1080

gaacuacuca acucgauccc acccgaugaa guuauuccca uuggagccgc caucgaagcc     1140

ggcauccuaa ucggcaaaga aaaccuacug guagaagacu cacuaaugau cgaaugcuca     1200

gcccgcgaca uccucgucaa aggagucgac gaaagcggag ccucccgauu caccguacua     1260

uucccuuccg gaacgccgcu cccagcccgc cgacaacaca cccuccaagc ccccggcucc     1320

aucuccuccg ucugccucga acucuacgaa agugauggca aaaacucagc caaagaagaa     1380

accaaauucg cgcaaguagu acuacaagac cucgacaaga aagaaaacgg acuacgcgac     1440

auccuagccg uacucaccau gaaacgcgac ggaucacucc acguaaccug cacagaccaa     1500

gaaacaggca aaugcgaagc uaucuccaua gaaaucgccu caugaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  2369
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt11)

<400>  2369
gggagaaagc uuaccauguc cgugguagga cucgacgucg ggagccaaag cugcuacaua       60

gcgguagcca gggcaggcgg gauagagacg aucgccaacg aguucuccga ucgcugcaca      120

cccagcguca ucagcuuugg uucuaaaaac aggacuauag gaguggccgc caaaaaccaa      180

caaauaaccc augcaaacaa caccgucagc aacuucaaac gauuccacgg acgugccuuc      240

aacgaccccu uuauacaaaa agaaaaagaa aaccuauccu acgaccuagu cccccucaag      300

aauggaggcg ugggcaucaa aguuauguau augggagaag aacaccuguu cucaguagaa      360

cagauaaccg ccaugcuacu aacaaaacug aaggaaaccg cagagaacag ucugaagaaa      420

ccugucaccg acugcguaau cuccguaccc uccuucuuca ccgacgcaga acggagaucc      480

guacuagacg cagcccaaau aguaggccua aacugccucc gccugaugaa cgauaugacg      540

gccguagcac ucaacuaugg gauuuacaaa caagaccucc caagccucga cgaaaaaccc      600

cgcauaguag ucuucgucga caugggacac ucagcauucc agguaagcgc augcgccuuc      660

aacaaaggaa aacucaaagu ccuaggcacg gcuuucgacc ccuuccuagg cgggaaaaau      720

uucgacgaga aacucgucga acacuucugc gccgaguuca aaaccaaaua caaacucgac      780

gcaaagagca aaauccgagc ccuccuacgc cuauaccagg aaugcgaaaa gcuaaagaaa      840

cugauguccu ccaacuccac cgaccuaccc cuaaacaucg aauguuucau gaacgacaag      900

gacgucagcg gaaagaugaa cagaucccag uucgaggagc ucugcgccga gcuacuccaa      960

aagauagaag ucccccucua cagccuucuc gaacagaccc accucaaagu agaagacguu     1020

ucagccgucg aaaucgucgg cggagcaaca cgcauccccg cggucaaaga acgcaucgcc     1080

aaauucuucg ggaaggacau auccaccacc cuaaacgcag acgaagcagu ggcacgcggg     1140

ugugcccucc agugcgccau ccuaagcccc gcauucaaag uacgagaguu cucaguaacc     1200

gaugccgucc cguucccaau aagccugaua uggaaccacg acagcgagga caccgaaggu     1260

guccacgaag ucuucagucg aaaccacgcg gccccauucu caaaaguauu aacguuccuc     1320

cgacgcggac ccuucgaacu cgaagcauuc uacagcgacc cgcaaggcgu accguacccu     1380

gaggcaaaga uuggcagguu cguaguccag aacgucuccg cacagaaaga uggcgagaaa     1440

agccgcguaa aggucaaagu ccgagucaac acacacggaa ucuucaccau uuccaccgcc     1500

ucaaugguag aaaaaguccc cacagaagaa aacgagauga gcucugaagc cgacauggag     1560

ugccucaacc aacgcccacc cgaaaacccc gacaccgaca agaacgucca acaagacaac     1620

agcgaagcag gaacccagcc ccaaguccaa accgacgcac aacagaccag ccagagccca     1680

cccucccccg agcucacauc agaagaaaau aagaucccag acgcagacaa ggccaacgaa     1740

aagaaagucg accagccccc ggaggccaag aaacccaaaa ucaaaguggu caacguagaa     1800

cuccccaucg aagcaaaccu ggucuggcag cuagguaaag acuuacuaaa cauguacauc     1860

gaaaccgaag gcaaaaugau aaugcaagau aaacucgaaa aagaacgcaa cgacgccaaa     1920

aacgcagucg aagaauacgu auacgaguuc cgggacaaac uaugcggccc auacgaaaaa     1980

uucaucugug aacaagacca ccaaaacuuu cuacgucuau uaaccgaaac cgaagacugg     2040

cucuacgaag aaggcgaaga ccaagcaaaa caggcuuacg ucgauaaacu ggaagaacua     2100

augaaaaucg gaacgccggu caaagugcgg uuccaagaag cagaagaacg ucccaaaaug     2160

uucgaggaac ucggacaaag acuccaacac uacgcgaaaa ucgccgccga cuuccgcaac     2220

aaagacgaga aguacaacca caucgacgaa ucagaaauga agaaaguaga aaagucgguc     2280

aacgaaguaa uggaauggau gaacaacgua augaacgccc aagccaaaaa gucccucgac     2340

caagacccag ucguccgagc acaagaaauc aaaaccaaaa uuaaggaacu gaacaauacc     2400

ugcgagcccg ucguaacgca accgaaacca aaaauagaau cccccaaacu cgaacgaacc     2460

cccaacgggc cgaacaucga caagaaagaa gaagaccucg aggacaaaaa caacuucgga     2520

gcagaaccac cacaccaaaa cggcgaaugc uacccaaacg agaaaaacag cgucaacaug     2580

gaccucgauu aaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  2370
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt11)

<400>  2370
gggagaaagc uuaccauggc agacaagguc aggcggcaac gaccacggag gcgcguaugu       60

ugggcgcuag ucgcaguccu acuugcggac cuacuggcac uaagcgacac gcuggcaguu      120

auguccguag accucggaag cgaaucgaug aaagucgcga ucgucaaacc cggcguccca      180

auggaaauag uccuaaacaa ggaaagccgc aggaagaccc cggugauagu gacacucaaa      240

gagaacgaac gcuucuucgg agacucggcc gcgagcaugg ccauaaagaa ccccaaagca      300

acgcuaagau acuuccaaca ccuccucggg aaacaagcag acaacccaca cguggcacuc      360

uaccaggcaa gguucccaga acacgagcug acauucgacc cgcaacgcca aacgguacac      420

uuccaaauau caucacaacu gcaauuuuca cccgaagaag uccuaggaau ggugcucaac      480

uacuccagau cauuagccga agauuucgcc gaacaaccaa uaaaagacgc agucauaaca      540

guacccgucu ucuucaacca ggcagaacgc cgagcagucc uacaagccgc gaggauggca      600

ggccuuaaag uccuccaacu gaucaacgac aacaccgcaa cagcacugag cuauggcguc      660

uucagacgga aggacauaaa caccaccgca cagaauauaa uguuuuacga caugggaagc      720

ggauccacag ugugcaccau aguaaccuac caaaugguga aaacgaagga ggccggcaug      780

caaccucagc uccaaauccg agggguagga uucgaccgga cacucggcgg gcuagaaaug      840

gaacuacggc uaagagaaag auuagcggga cuguucaacg aacagcgaaa aggacaacga      900

gcgaaagacg ucagggaaaa cccccgcgcg auggcaaagc uccuucgaga ggcaaaccgc      960

cugaaaacag ugcugucagc gaacgcggac cacauggcuc aaauagaagg acucauggac     1020

gacgucgacu ucaaagcaaa gguaacacga gucgaauuug aagaacuaug cgcggaucua     1080

uucgaaagag ugcccggacc cguacagcaa gcacugcagu ccgccgaaau gucccuagau     1140

gaaauagaac aaguuauccu agucggcggc gccaccagag uaccacgagu gcaggaagua     1200

cuacucaaag ccguaggcaa ggaggaacua gggaaaaaca uaaacgccga cgaagcagca     1260

gcgauggggg caguuuacca agccgccgca cucagcaagg cauucaaagu caaacccuuc     1320

gucguacgag acgccgucgu auacccgaua cugguagagu ucacacgcga aguggaggag     1380

gaaccaggaa uacauagccu gaaacacaac aagcgaguuc ucuucagccg aaugggcccc     1440

uacccccaaa gaaaagugau caccuucaac cgguacagcc acgacuucaa cuuccacaua     1500

aacuacggcg accucggauu cuuggggccc gaagaccuca ggguauucgg gagccaaaac     1560

cugacaacag ucaaacucaa aggcguaggc gacagcuuca aaaaguaccc agauuacgaa     1620

aguaaaggca uaaaagcaca cuucaaucuu gacgaaagcg gagugcucuc gcucgaccgc     1680

guggagagcg ucuuugaaac ccuaguagag gacagcgccg aagaagaaag cacgcuaaca     1740

aagcugggaa acaccauauc cucacuauuc ggagggggaa cgacaccaga cgcaaaagag     1800

aacggaaccg acaccgucca agaagaggaa gagagcccag cugaaggguc caaagacgag     1860

ccaggagaac aaguugaacu uaaagaagaa gcggaggccc cuguugagga cggaagccaa     1920

ccgcccccac ccgaacccaa aggcgacgcc acaccagaag gcgaaaaggc aaccgagaag     1980

gaaaacggag acaaauccga agcccaaaaa ccaagcgaaa aagcagaggc cggcccagaa     2040

ggggucgcgc ccgcaccgga aggggagaag aagcaaaaac ccgcacgaaa acgcagaaug     2100

guggaagaaa ucggaguaga gcuagucgua cuagaccuac cagaucugcc ggaagacaaa     2160

cuagcacaau caguucagaa acuucaagac uugacccuac gggaccugga aaaacaagaa     2220

agagaaaaag cagccaacag ucucgaagcc uucaucuucg agacacaaga caaacuguac     2280

caacccgagu accaggaagu aagcacagaa gaacagagag aagaaaucag uggaaaacug     2340

agcgcugcgu caacauggcu agaagacgaa gggguaggug caacaaccgu caugcuuaaa     2400

gaaaagcucg ccgaacugcg caaacucugc caagggcuau ucuuccgagu agaagagagg     2460

aagaaauggc cagaaaggcu auccgcacua gacaaccuac ugaaccacuc gagcauguuc     2520

cuaaagggag caagacucau accagagaug gaccaaauau ucaccgaggu ggaaaugaca     2580

acacucgaaa agguaauaaa cgaaacgugg gccuggaaaa acgccacacu agcagagcaa     2640

gccaaacugc cagcaacaga gaaaccagua cugcuaucaa aggacaucga agcaaaaaug     2700

auggcacugg acagagaggu gcaauaccuc cucaacaaag caaaauucac aaaacccaga     2760

ccacgaccaa aagauaagaa cggaacacgc gcagagccac cccuaaaugc uucggcgagc     2820

gaucaagggg agaaaguaau acccccagcc gggcaaaccg aggacgccga gccgaucucc     2880

gaacccgaaa aggucgaaac aggcucagaa cccggggaua cagaaccacu ugaacucggc     2940

ggacccggag ccgagccaga acagaaggaa caaaguacag ggcaaaaacg cccccugaaa     3000

aacgacgaac uauagggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2371
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt11)

<400>  2371
gggagaaagc uuaccaugcc agaagaaacc caaacacaag aucaaccaau ggaagaagaa       60

gaaguggaaa ccuucgcguu ccaggcggaa auagcccaac uaaugucccu caucaucaac      120

accuucuaca gcaacaagga aaucuuccug cgagaacuua ucagcaacag cagcgacgcc      180

cucgauaaga ucagauacga aagccuaacu gacccaagca aacuagauag cgggaaagaa      240

cuccacauca accuaauacc caacaaacaa gaccggaccc ucacaauagu agacaccgga      300

aucggaauga caaaggcgga ccuuauaaac aaucugggaa ccaucgcgaa aagcgggaca      360

aaggcauuca uggaagcgcu ccaggcaggg gcagacauau caaugaucgg ccaauucgga      420

gucggcuucu acucagcgua ccuaguagcc gagaaaguaa ccgucauaac caaacacaac      480

gacgaugagc aguacgcgug ggagagcagc gcgggaggau cguucacagu gagaaccgac      540

acaggggaac cgaugggacg cggaacgaaa guaauacuac accucaaaga agaccagacc      600

gaauaccucg aagaaaggcg aauaaaagaa auagugaaga aacacuccca guucaucgga      660

uacccgauaa cacuauucgu ggagaaagag cgcgacaaag aggucagcga cgacgaagca      720

gaagaaaaag aagacaaaga agaggaaaag gaaaaagaag aaaaagaaag cgaagacaaa      780

ccagagaucg aagacguggg aagcgacgaa gaagaagaaa agaaagaugg agacaagaag      840

aaaaagaaga aaaucaaaga gaaauacaua gaccaagaag aacuaaacaa aacgaaacca      900

aucuggaccc ggaacccaga cgacauaacc aaugaagaau acggcgaguu cuacaaauca      960

cucacaaacg acugggaaga ccaccucgcc guaaaacacu ucucgguaga gggacaacua     1020

gaguuccgag cgcuccuguu cgugccaagg cgagccccau uugaccuguu cgagaauaga     1080

aagaagaaaa acaacauaaa acucuacguc cgccgggucu ucaucaugga caacugugaa     1140

gaacuaauuc cggaauaccu gaacuucauc cgcggcguag uggacagcga agaccugccg     1200

cucaacaucu cgagagaaau guuacaacaa agcaaaaucc ucaaaguaau aaggaagaac     1260

cucgugaaga aaugccugga auuauucaca gaacuagccg aagacaaaga aaacuacaag     1320

aaauucuacg agcaauucag caaaaacaua aaacugggca uccacgaaga cagccaaaac     1380

cgcaagaaac uauccgagcu ccuacgcuac uacaccuccg cauccgggga ugagauggug     1440

ucacuaaaag acuacugcac cagaaugaaa gaaaaccaaa aacacaucua cuacaucacg     1500

ggcgaaacaa aagaccaagu agcgaacuca gccuucgucg agcgccuacg aaaacacggg     1560

cuagaaguca uauacaugau cgaaccaaua gacgaauacu gcguccaaca acucaaagag     1620

uucgaaggaa aaacccucgu cagcguuacc aaagaaggcu uggagcuccc cgaagacgaa     1680

gaagagaaaa agaaacaaga agaaaagaaa accaaauucg aaaaccugug caaaaucaug     1740

aaggacauac uggaaaagaa aguagagaag gucguaguau caaacaggcu cgugaccagc     1800

cccugcugca uagucacauc uaccuacgga uggacggcca acauggaaag aauaaugaag     1860

gcccaagcac uccgcgacaa cucgacaaug ggcuacaugg cggccaagaa acaccucgag     1920

aucaaccccg accacuccau caucgaaacg cucaggcaga aagccgaagc agacaaaaac     1980

gauaaauccg ugaaggaccu cguaauacuc cuauaugaaa cggcccuucu aagcagcggg     2040

uucagccucg aagacccgca aacgcacgcg aacaggaucu accgaaugau caaacucggc     2100

cuugggaucg acgaagacga cccaacagca gacgacacga gcgcggccgu aacggaagaa     2160

augccaccac uagaaggcga cgacgacacg agcaggaugg aggaagugga cuagggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  2372
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt11)

<400>  2372
gggagaaagc uuaccaugga cagcucaaaa cuggacucgg gcaagggccu gcacauaaac       60

cuggucccga acaagcaaaa ccaaacacuc acgaucgugg acacgcgcau aggcaugacc      120

aagaccgacc ucauaaacaa ccucgggacc gugaccaaga gcgggaccaa ggccuucaug      180

gaggcccugc aagcggacgc ggacauaagc augaucggac acuucggcgu gggcuucuac      240

ucggccuacc ucguggccaa gaaagugacc gugaucucaa aacacaacaa cgacgagcaa      300

uacaccuggg aaucgagcgc gggcgggagc uucaccgugc gcacggacga guaaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  2373
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt11)

<400>  2373
gggagaaagc uuaccaugcc cgaagaagug caccacgggg aagaggaagu cgaaaccuuc       60

gccuuccagg ccgagauagc ccaacucaug agcuuaauca uaaacaccuu cuacuccaac      120

aaagaaaucu uccucagaga guugauauca aacgcaagcg acgcccugga caagauaaga      180

uacgaaagcc uaacagaccc aucaaaacug gacucaggaa aggaguuaaa aauagacauc      240

aucccaaacc cacaagaacg cacgcucacc cucguggaca ccggaauagg aaugacaaaa      300

gccgaccuca uaaacaaucu cggcacgaua gccaagagcg ggacaaaagc cuucauggag      360

gcccuacaag caggagccga cauaagcaug aucggacaau ucggcguagg cuucuacagc      420

gcauaccucg ucgccgaaaa ggugguagua aucacaaaac acaacgacga cgaacaauac      480

gccugggaaa gcagcgccgg cgggagcuuc acagucagag cagaccacgg cgaaccuaua      540

ggacgcggga cuaaaguaau ccuccaccua aaggaagacc aaaccgaaua cuuagaagag      600

cgcaggguca aggaagucgu caaaaaacac agccaguuca ucggcuaccc cauaacccuc      660

uaccuggaaa aagagaggga aaaggaaaua agugacgacg aggccgagga agaaaaagga      720

gaaaaagaag aagaagacaa agacgacgaa gaaaagccca agaucgaaga cguaggaagc      780

gacgaagaag acgacucagg aaaggacaag aaaaaaaaaa cgaaaaaaau caaagagaaa      840

uacaucgacc aagaagagcu gaacaaaaca aaaccaaucu ggaccaggaa ccccgaugac      900

aucacacaag aagaauacgg ggaauucuac aaaucgcuaa caaacgacug ggaggaccac      960

cucgcgguaa agcacuucag cguggaagga caacucgaau ucagagcacu acuauucauc     1020

ccaaggagag cgccauucga ccuguucgaa aacaagaaaa aaaaaaacaa cauaaagcua     1080

uacguccgac gagucuucau aauggacuca ugcgacgaac ugaucccaga auaccuaaac     1140

uucauccggg gcguaguaga cuccgaagac cucccacuca acaucagccg agaaaugcua     1200

caacagagca agauacugaa agugaucaga aaaaacaucg uaaaaaagug ccuagaacua     1260

uucagcgaau uagcagagga uaaagaaaac uacaagaaau ucuacgaagc cuucagcaag     1320

aaccuaaaac ugggcauaca cgaagacagc accaaucgaa ggcgccuaag cgaacuacua     1380

agauaccaca caagucagag cggcgacgag augacgagcc uauccgaaua cguuagccgg     1440

augaaagaaa cgcaaaaguc aauauacuac aucaccggag agagcaagga acaaguagcg     1500

aacucggcau ucgucgaacg cgugcgaaag cgcggauucg aagucguaua caugacggag     1560

cccaucgacg aguacugugu acaacagcuc aaagaauucg acggcaaaag ccuagucuca     1620

guaaccaaag aaggacuaga auugcccgaa gacgaagaag agaagaaaaa aauggaagaa     1680

ucaaaagcca aauucgagaa cuugugcaag cugaugaaag agauccuaga caaaaaggua     1740

gaaaagguca cgaucucaaa ccggcuggug agcucgcccu gcugcaucgu cacgagcaca     1800

uacggcugga cagcaaacau ggaacgaaua augaaagcac aagcccucag agacaacuca     1860

accauggggu acaugauggc caagaaacac cucgaaauaa accccgacca cccuauagua     1920

gaaacgcuca ggcaaaaggc cgaagcagac aaaaacgaca aagccguaaa agaccucgug     1980

guccugcucu ucgaaacagc ccuacucuca agcggauuuu cacuggagga cccacaaacc     2040

cacagcaaca gaaucuaccg aaugauuaag cucggacugg guauugacga ggacgaagua     2100

gccgcggaag agcccaacgc ggcagucccc gacgaaaucc cgccccugga aggggacgag     2160

gacgcaucaa gaauggaaga ggucgacuag ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  2374
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt11)

<400>  2374
gggagaaagc uuaccaugag agcccuaugg gugcucgggc ucugcugcgu acuacucacg       60

uucggaucag uccgagcaga cgacgagguc gacgucgacg gaacggucga agaagaccua      120

ggaaaaagcc gcgaaggcag ccggacagac gacgaggucg uccagcgaga ggaagaggca      180

auacaacucg acggucuaaa cgccagccag auacgcgagc uccgggagaa aagugaaaaa      240

uucgccuucc aagcagaggu caacagaaug augaaacuca uaauuaacuc ccuauacaaa      300

aacaaagaaa uauuccugcg ggaacuaauc uccaacgcca gcgacgccuu agacaaaaua      360

cgacucauca gccugacaga cgaaaacgcc uugagcggga acgaggaacu aaccgugaaa      420

auaaaaugcg acaaagagaa gaaccugcua cacguaacgg auacgggagu aggcaugaca      480

cgagaagaac ucgucaaaaa ccucggaacc auagccaaga gcggcacaag cgaguuccuc      540

aacaaaauga cagaagccca ggaggacggc caaucaacga gugagcuuau aggccaauuc      600

gggguagggu ucuacagcgc guuccuagua gcggacaaag uaauagucac aagcaaacac      660

aauaacgaua cacagcacau augggaauca gacagcaacg aauuuagcgu gaucgcggac      720

ccgcggggaa acacgcuugg cagaggaacc accaucacuc uaguacucaa ggaagaggcu      780

ucagacuauc uagaacugga cacaaucaaa aaccucguaa agaaauacag ccaauucaua      840

aacuucccga uauacgucug gagcucgaaa acagaaacag uagaggagcc gauggaggag      900

gaagaggcag ccaaagaaga aaaagaagaa ucggacgacg aagcggcagu cgaagaagaa      960

gaggaagaga aaaagcccaa aaccaagaaa guagagaaaa ccguauggga cugggaacuc     1020

augaacgaca uaaaacccau auggcagcgc ccgagcaaag aagucgagga agacgaauac     1080

aaagccuucu acaagagcuu cagcaaagaa agcgacgacc cgauggccua uauacacuuc     1140

acagccgaag gagaggugac guucaaaagc auccucuucg ucccgacgag cgcccccagg     1200

ggacucuucg acgaauacgg gaguaagaaa agcgacuaca ucaaacuaua cguccgacgg     1260

guguucauaa ccgacgacuu ccacgacaug augcccaagu accugaacuu cgucaaagga     1320

gugguagauu cagaugaccu gccacucaac guaagcagag agacgcucca acagcacaaa     1380

cugcucaagg uaauacgcaa gaagcuaguc aggaaaacgc ucgacaugau caaaaagauu     1440

gcggacgaua aguacaacga cacguucugg aaggaguucg gaacgaacau aaaacuaggc     1500

guaaucgaag accacagcaa ccgaacaaga cucgcaaaac uccucagauu ccagagcagc     1560

caucacccca cagacauaac aagccuggac caauaugugg aacgaaugaa agaaaaacag     1620

gacaaaaucu acuucauggc gggauccagc cgcaaagagg cagaaagcag ccccuucgua     1680

gaacgacucc uaaagaaagg cuacgaaguc aucuacuuga ccgaaccagu agacgaauac     1740

ugcauccagg cccuucccga guucgacggc aagagauucc aaaacgucgc gaaggaaggc     1800

guaaaauucg acgaaagcga gaagacgaaa gaaucgaggg aagcagucga gaaagaguuc     1860

gaaccacugc ucaacuggau gaaagacaaa gcgcuaaaag acaagauaga aaaagcggua     1920

guaucgcaac ggcugaccga aagcccaugc gcccuagucg cgagccaaua cggcuggagc     1980

gggaacaugg aaagaauuau gaaagcgcaa gccuaccaga caggaaagga caucagcacc     2040

aacuacuacg ccagccaaaa gaagacguuc gaaaucaacc caagacaccc gcuaauaaga     2100

gacaugcuac gaaggaucaa ggaagacgag gacgacaaga ccgugcucga ccucgcgguc     2160

gugcuauucg aaacggccac gcuuagaagc ggauaccugc uacccgacac gaaagccuac     2220

ggcgaccgaa ucgaacgcau gcuaaggcuc agucuaaaca uagaccccga cgcgaaagug     2280

gaagaggaac cagaggagga accagaagaa acggcagagg acaccaccga ggacacagaa     2340

caggacgagg acgaggagau ggacgucgga acggacgaag aggaagaaac cgcaaaggaa     2400

ucgaccgcag aaaaggacga gcuauaagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  2375
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt11)

<400>  2375
gggagaaagc uuaccauggc ccgcgaauua cgagcccuac uacuaugggg ucgccgacuc       60

cgcccacuac uccgagcccc cgcacucgcc gcagucccug gaggaaaacc cauacucugc      120

ccccgaagaa caacagcuca acucggcccc cgucgcaacc cagccugguc gcuccaggcc      180

ggccgacucu ucuccacaca aaccgccgaa gacaaagaag aaccccucca cagcauaauc      240

agcagcaccg aguccguaca aggaagcacc uccaaacacg aguuccaggc cgaaaccaag      300

aaacuucucg acaucguagc ccgaagucua uacuccgaaa aagaagucuu cauccgagaa      360

cuuaucucua acgcauccga cgcacucgaa aaacuacgac acaaacucgu aucagacggu      420

caagcacuac ccgaaaugga aauacaucua caaaccaacg cagaaaaagg uaccauaaca      480

auucaagaca cgggaauagg aaugacgcag gaggaacucg ucucaaaccu aggcacuaua      540

gcccgaagcg gcagcaaagc cuuccucgac gcccuccaaa accaagccga agccuccucc      600

aaaaucaucg gucaguucgg cguaggcuuc uauuccgccu ucaugguagc agaccgaguc      660

gaaguauauu cucgcucagc agcccccggc ucccuaggcu accaauggcu auccgacggc      720

agcggcgugu ucgaaauagc agaagccucg ggcguccgua caggcaccaa aaucaucaua      780

caccuaaaaa gcgacugcaa agaauuuagc ucagaagccc gcguccgaga cgucgucacc      840

aaauauucaa auuucgucuc auuuccacuc uaucuaaacg gcagacgcau gaacacgcuc      900

caagccaucu ggaugaugga cccaaaagac guccgcgaau ggcagcauga agaguucuac      960

cgcuacguag cacaagcgca cgacaaacca cgcuacaccc uccacuacaa aacggacgcc     1020

ccacuaaaca uccgcuccau cuucuacgua ccggacauga aacccagcau guucgacgua     1080

ucccgcgaac ucggcucauc gguagcacuc uacucuagga aaguccucau acaaacaaaa     1140

gccaccgaca uccuaccaaa auggcuucga uucaucagag gcgucgucga cagugaagac     1200

aucccccuca accucucacg agaacuccua caagaauccg ccuuaauccg aaaacuccgc     1260

gacguacuuc aacagcgucu cauaaaauuc uucaucgauc aauccaagaa agaugcagaa     1320

aaauacgcca aauucuucga agacuacggc cucuucaugc gggaaggcau cguaacagca     1380

accgagcaag aggucaaaga ggacauagca aaacuccuca gauacgaguc cagcgcccuu     1440

cccucgggcc aacuaacuag ccuaagcgaa uacgccucac guaugagagc aggcacccgc     1500

aacaucuacu accucugcgc cccaaaccga caccucgcag aacacucacc cuacuacgag     1560

gccaugaaaa agaaagacac cgaaguccug uucugcuuug aacaauucga cgaacugacc     1620

cuacuacacc ucagagaguu cgacaaaaag aaacucauca gcgucgagac ggacaucguc     1680

guagaccacu acaaagaaga aaaauucgag gaccgcagcc cagccgcaga augccuaucg     1740

gaaaaagaaa ccgaagaacu cauggccugg augcggaacg uccuaggcuc cagaguaacc     1800

aacguaaaag ucacacucag acuagacacc caccccgcca uggucaccgu acuagaaaug     1860

ggagcugccc gacacuuccu acgaaugcaa caacuagcaa aaacacagga ggaacgcgcc     1920

caacuccuuc aaccaacccu cgaaauaaac ccccgacacg cccuaauaaa gaaacuaaau     1980

caacugaggg ccuccgagcc cggacucgcc caacuucuag ucgaccagau cuacgaaaac     2040

gccaugaucg cggcaggccu aguagacgac ccccgcgcca uggugggacg acuaaaugaa     2100

cuacuuguca aagcacuaga gcgacauuaa ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  2376
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt11)

<400>  2376
gggagaaagc uuaccauggg caaaaucucc ucccucccca cccaacucuu caaaugcugc       60

uucugcgacu uccuaaaagu caaaaugcac accauguccu ccucccaccu cuucuaccua      120

gcccucugcc uccuuaccuu caccuccucc gccaccgccg gccccgaaac ccucugcggc      180

gccgaacucg ucgacgcccu ccaauuuguc ugcggcgacc gcggauucua cuucaacaaa      240

cccaccggcu acggcuccuc cucccgccgc gcaccccaaa ccggcaucgu cgacgaaugc      300

ugcuuccgcu ccugcgaccu ccgccgccuc gaaauguacu gcgcaccccu caaacccgcc      360

aaauccgccc gcuccguccg cgcccaacgc cacaccgaca ugcccaaaac ccaaaaagaa      420

guccaccuca aaaacgccuc ccgcggcucc gccggcaaca aaaacuaccg cauguaagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  2377
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt11)

<400>  2377
gggagaaagc uuaccauggg cauccccaug ggcaaaucca ugcucguccu ccuaaccuuc       60

cucgccuucg ccuccugcug caucgccgcc uaccgacccu ccgaaacacu cugcggcggc      120

gaacucgucg acacccucca auucgucugc ggcgaccgcg gcuucuacuu cucccgcccc      180

gccucccgcg ucucacgccg cucccgcggc aucgucgaag aaugcugcuu ccgcucuugc      240

gaccucgccc uccucgaaac cuacugcgcc acccccgcaa aauccgaacg cgacgucucc      300

acccccccca caguacuccc cgacaacuuc ccccguuacc ccgucggcaa auucuuccaa      360

uacgacaccu ggaaacaauc cacccaacgc cuccgccgcg gacuacccgc ccuacuccgc      420

gcccgccgcg gccacguccu agcaaaagaa cucgaagccu uccgagaagc caaacgccac      480

cgcccccuca ucgcccuccc cacccaagac cccgcccacg gaggcgcccc ccccgaaaug      540

gccuccaacc gcaaauaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  2378
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt11)

<400>  2378
gggagaaagc uuaccaugaa cuccuucucc accuccgccu ucggccccgu cgccuucucc       60

cucggccucc uacucguacu ccccgccgcc uucccagccc ccgucccccc aggcgaagac      120

uccaaagacg ucgccgcccc ccaccgccaa ccucucaccu cauccgaacg caucgacaaa      180

caaauacgcu acauccucga cggcaucucc gcccuccgca aagaaaccug caacaaauca      240

aacaugugcg aauccucaaa agaagcccuc gccgaaaaca accuaaaccu ccccaaaaug      300

gccgaaaaag acggcugcuu ccaauccggc uucaacgaag aaacaugccu cgucaaaaua      360

aucaccggac uccucgaauu cgaagucuac cucgaauacc uacaaaaccg cuucgaauca      420

uccgaagaac aagcccgcgc cguccaaaug ucaaccaaag uccucaucca auuccuccaa      480

aaaaaagcca aaaaccucga cgccaucaca acccccgacc ccaccaccaa cgccucccua      540

cucaccaaac uccaagccca aaaccaaugg cuccaagaca ugaccaccca ccucauccuc      600

cgcuccuuca aagaauuccu ccaauccucc cuccgcgccc uccgacaaau guagggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  2379
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt11)

<400>  2379
gggagaaagc uuaccaugcc acuccugugg cuccgcggau uccuccuagc aagcugcugg       60

auaauaguac gaagcucccc aacaccaggc agcgagggcc acagcgccgc acccgacugc      120

ccauccugcg cacucgccgc ccucccaaaa gacgucccga acagccaacc cgaaaugguc      180

gaagcgguca agaaacacau acucaacaug cuacaccuaa agaaacgccc agacguaaca      240

cagccagucc ccaaagccgc acuacuaaac gcgauccgaa aacuacacgu aggcaaagug      300

ggagaaaaug gcuacgucga aaucgaagac gacauaggca gacgagcaga aaugaacgaa      360

cuaauggaac aaacaaguga aauaaucaca uucgccgaga gcggcacagc ccggaaaacc      420

cuacacuucg aaaucucaaa agaaggaucc gaccucagcg ucguagaacg agccgaagug      480

uggcuauucc ucaaaguccc caaagccaac agaaccagaa ccaaagucac aaucagacuc      540

uuccaacagc aaaaacaccc gcaaggaagc cucgacacag gcgaagaagc agaggaaguc      600

ggacucaaag gugaacgcag cgaacuccuc cuguccgaaa aagucgucga cgcccgaaaa      660

agcacauggc acguauuccc aguaagcagc uccauccaac gccugcuaga ccaagggaaa      720

ucaagccugg acguccgcau agcaugcgaa caaugccaag aaagcggcgc aagccuagua      780

cuacuaggga aaaagaaaaa gaaagaggaa gaaggagaag gaaagaagaa aggaggcgga      840

gaagguggag caggcgccga cgaagaaaaa gaacaaagcc accggccauu ccucaugcua      900

caagccagac aaagcgaaga ccacccacac cgacgacgcc gacgaggccu cgaaugcgac      960

ggaaaaguca auauaugcug caagaaacaa uucuucguca gcuucaaaga cauagggugg     1020

aacgacugga ucauagcccc aagcggcuac cacgccaacu acugcgaagg agaaugccca     1080

agccacaucg ccggaacauc cgggagcagc cugagcuucc acagcacggu aauaaaccac     1140

uaccgcaugc gcggccacag cccauucgcc aaccucaaaa gcugcugcgu acccaccaaa     1200

cuacgcccaa uguccaugcu cuacuacgac gacgggcaga acaucauaaa gaaagacaua     1260

cagaacauga ucgucgaaga gugcggcugc uccuaaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  2380
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt11)

<400>  2380
gggagaaagc uuaccaugga cggccuacca ggacgagccc ucggcgccgc augccuccuu       60

cuccucgccg ccggaugguu aggccccgaa gcauggggcu cacccacccc accacccacc      120

ccagccgcac ccccaccccc acccccacca ggauccccag gaggcagcca agacacaugc      180

accucgugcg gaggcuucag acgcccugaa gaacuaggcc gagucgacgg cgacuuccuc      240

gaagccguga aacgccauau acucucccga cuccaaaugc gcggccgacc caacauaacc      300

cacgccguac ccaaagcagc uaugguaacc gcccuccgca aacuccaugc cggcaaaguc      360

cgagaagacg gccgagucga aaucccccac cucgacggac acgccucccc cggcgccgac      420

ggccaagaac gaguaucaga aaucaucucc uucgcugaaa ccgacggccu ggcauccucc      480

cgaguccgcc ucuacuucuu uauauccaac gaagguaacc aaaaccucuu cgucguccaa      540

gccucacuau ggcucuaccu aaaacuacuc cccuacguac ucgaaaaagg cagccgccgc      600

aaaguccgcg uaaaagucua uuuccaagaa caaggccacg gcgaccgcug gaacauggua      660

gaaaaacgug ucgaccucaa aagaucaggc uggcacaccu ucccccuaac cgaagcuauc      720

caagcacucu ucgaacgagg agaacgaaga cucaaccucg acguacaaug cgacucuugc      780

caagaacucg cgguaguccc aguauucguc gaccccggcg aagaauccca cagacccuuu      840

guaguaguac aagcgcgacu cggcgacucu cgacaccgaa uccgcaaacg cggccuagaa      900

ugcgacggac gcacaaaccu cugcugccgc caacaauucu ucauagacuu ccgccuaauc      960

ggcuggaacg acuggaucau agcccccacc ggcuacuacg gcaauuacug cgaaggcuca     1020

ugccccgcau accucgccgg cguccccggc ucagcauccu cuuuccacac cgccgucgua     1080

aaccaauaca ggaugcgcgg acuuaaccca ggaacaguca auuccugcug cauacccacc     1140

aaacucagca ccauguccau gcucuacuuc gacgacgaau acaacaucgu caaacgcgac     1200

guccccaaca ugaucgucga agaaugcgga ugcgcauaag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  2381
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt11)

<400>  2381
gggagaaagc uuaccauggc ccuccguguu uuacugcuca cagcacucac acugugucac       60

ggauucaacc uagacaccga aaaugcaaug accuuccaag aaaacgcacg cggcuucgga      120

caaucgguag uccaacuaca agguucgcgc guagucgucg gcgccccuca agagauaguc      180

gcugcaaacc aacgaggcuc acucuaccaa ugcgacuacu caaccggguc augcgaacca      240

aucagacucc aagucccagu cgaagcaguc aacaugagcc ugggucucag ccucgccgcc      300

acaaccucac ccccacaacu cuuagcaugc ggaccaaccg uccaucagac cugcucggaa      360

aacaccuacg uaaaaggccu augcuuucuc uuugggucca accuacgaca gcagccccaa      420

aaauuccccg aagcccuccg aggauguccg caagaagaca gcgacauagc cuuucucauu      480

gacggcuccg gauccauaau accacacgac uuccgccgga ugaaggaauu ugucucaaca      540

guuauggaac aacucaagaa auccaaaaca cucuucuccc ugaugcaaua cagcgaggag      600

uucagaaucc acuucaccuu caaagaguuc cagaacaacc ccaacccccg cucacuggua      660

aaaccaauaa cucaacuccu cggcaggaca cacacggcca cgggcaucag gaaggucgug      720

cgcgaacucu ucaacauaac aaauggugca cgcaaaaacg ccuucaaaau ccuugugguc      780

auaaccgacg gcgaaaaauu cggggaccca uuaggauacg aagacguaau ccccgaagcg      840

gacagagagg gaguaauccg auacgucauc ggcguugggg acgccuuccg uagcgaaaaa      900

ucccgccagg aacucaacac aauugccucc aaaccgcccc gagaccacgu cuuccaaguc      960

aacaacuucg aagcccucaa aaccauccaa aaccaacucc gagagaaaau auucgccaua     1020

gaaggaaccc aaaccggcag cuccagcucc uucgaacaug aaauguccca agaaggcuuc     1080

agcgccgcga ucaccuccaa cggcccucua cucucuaccg ucggaucaua cgacugggcu     1140

ggcggcgucu uccuuuacac cuccaaggaa aaaucgacau ucaucaacau gaccagaguc     1200

gauucugaca ugaacgacgc auaucucggc uacgccgcug cuaucauucu acgcaacaga     1260

gugcaaucuc uaguauuagg agccccucgu uaccaacaca ucggccuagu ggcaauguuc     1320

cgucaaaaca ccgggaugug ggaaagcaac gcgaacguca agggcaccca aaucggcgca     1380

uacuucggag cuucucucug cucuguggac gucgacucaa acggaagcac ugaucucguu     1440

cuuaucggag caccccacua cuaugagcag acucgaggag gccaaguauc agucugucca     1500

cucccccgug gccgagcccg cuggcaaugc gacgcgguuc uauauggcga acaaggucaa     1560

cccuggggca gguucggugc cgcgcucacc guccuuggag acgucaacgg cgacaaacuc     1620

accgacguag caaucggcgc accuggcgag gaagacaacc gcggcgcagu guaccucuuc     1680

cacggcaccu ccggcagcgg caucucaccc ucccacucac aacgcauagc cggcucuaaa     1740

cuguccccca gacugcaaua cuucgggcaa agccuauccg guggacaaga ccucacgaug     1800

gacggccuag uagaucugac gguuggcgcg caagggcaug uacuucuacu acgaucccaa     1860

ccaguacuac gugucaaggc aaucauggag uucaauccac gggaagucgc acgaaacguc     1920

uucgaaugca acgaccaagu ugucaagggc aaagaagccg gcgaagucag agugugucug     1980

cacguacaaa agagcacacg ugaucgacug cgagaaggac aaauccaguc cguggucacc     2040

uacgaccuag cccuagacuc cggaagaccc cacagccgug ccgucuucaa cgaaaccaaa     2100

aauucaaccc gccggcaaac ccaggugcua ggccuuaccc aaacuugcga gacgcucaaa     2160

cuacaacugc ccaacuguau cgaagaccca gucucaccaa ucguacuacg ccuuaauuuu     2220

ucccuagucg gcacaccccu cucagcauuc ggaaaccucc gacccguccu cgccgaagac     2280

gcccaacgac uuuucaccgc ccuauucccc uucgaaaaga acugcggcaa cgacaacaua     2340

ugucaagacg accucagcau caccuucucu uucaugucgc ucgacugccu agugguaggc     2400

ggaccccgag aauuuaacgu cacagucacc guaagaaacg acggagagga uuccuacaga     2460

acgcaaguua cauucuucuu cccgcucgac cucucguacc gcaaagucuc gacccuucaa     2520

aaccaacgau cucaacgauc uuggaggcuc gcaugugaau cagccucguc aacagaagua     2580

aguggcgccc ucaaaucgac cuccuguucc auaaaccacc caaucuuccc cgagaacagc     2640

gaagucacau ucaacauaac auucgacguu gacucuaaag caucacucgg caacaaacuc     2700

uuacugaaag ccaacgucac cagcgaaaac aacaugccaa gaacaaacaa aacagaguuc     2760

caacucgaac ucccagucaa guaugccgua uacauggucg ucaccagcca cggaguaucc     2820

acaaaauacc ucaacuuuac cgccagcgaa aacacgucca gaguaaugca acaccaauac     2880

cagguaucca accuugguca acgcagucua cccaucuccc uaguguuccu cguucccguc     2940

agacuaaacc agacaguaau augggaccgu ccacaaguaa cauucucuga aaaccucucc     3000

uccacauguc acacuaaaga acgacucccu agccauuccg acuuucuugc agagcuucgc     3060

aaagccccug uugugaacug cucaaucgcg guaugccagc gcauacagug cgacauacca     3120

uucuuuggga uacaggaaga guucaacgcg acucucaaag guaaccucag cuucgacugg     3180

uauaucaaga ccucacauaa ccaccuccua auaguaucca cagccgaaau ccucuucaac     3240

gacagcgucu ucacauugcu gcccggccaa ggagcuuucg uacgaucgca gacagaaacu     3300

aaaguagaac cuuucgaagu cccgaacccg cucccgcuaa ucgucggauc cuccguuggc     3360

gggcuacucc uucuugcccu caucacagca gcacuguaua agcucggcuu cuucaagcgc     3420

caauacaaag auaugauguc cgaaggcggc ccgcccgggg ccgaacccca guaaggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  2382
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt11)

<400>  2382
gggagaaagc uuaccauguu cucccucaaa accuuaccgu uccuccuacu acuacacguc       60

caaaucucca aagccuuccc ugucuccagc aaagagaaaa acacuaaaac cguacaggac      120

uaccucgaaa aauucuacca acuacccuca aaccaguacc aguccacccg caaaaacggc      180

acaaacguga ucgucgaaaa gcuaaaagaa augcaacgcu ucuucggccu aaacgucaca      240

ggcaaaccca acgaagaaac ccucgacaug augaagaaac cccgaugcgg cguccccgac      300

uccggcggcu ucaugcucac acccgguaac cccaaauggg aacgaaccaa ccuaaccuac      360

cgcauacgaa acuacacacc ccaacucuca gaagccgaag ucgaacgagc uaucaaagac      420

gcauuugaac ucugguccgu cgcaucaccc cucaucuuca cccgcaucuc ucaaggcgaa      480

gccgacauaa auaucgccuu cuaucaaaga gaccacggcg acaacucccc cuucgacggc      540

ccgaacggua uccucgcaca cgccuuccaa ccaggccaag gaaucggcgg cgaugcccac      600

uucgacgcag aagaaaccug gacaaacacc ucagccaacu acaaccucuu ccucgucgcc      660

gcgcacgagu ucggacauuc ccucggccua gcccacuccu ccgaccccgg ugcacucaug      720

uacccaaacu acgccuuccg cgaaaccagc aacuacucac ucccccaaga cgacauagac      780

ggcauccaag ccauauacgg acuaucaucc aaccccaucc agccaaccgg acccucaacc      840

cccaaacccu gcgauccauc ccucaccuuc gacgccauca ccacccuacg uggagagauc      900

cucuucuuca aagaucgaua uuucuggcgc cgacaccccc aacugcaacg gguugaaaug      960

aacuucauca gccucuucug gccuucacua cccaccggaa uccaagccgc cuaugaagac     1020

uuugaccgcg accucaucuu ccucuucaaa ggaaaccaau acugggcccu cucggguuac     1080

gacauccuuc aaggcuaccc uaaagacaua ucaaacuacg gauucccauc guccguccaa     1140

gccaucgaug ccgcaguuuu cuaccgcucc aaaaccuacu ucuucgucaa cgaccaauuc     1200

uggcgcuaug acaaccaacg ccaauucaug gaaccaggau accccaaauc caucuccggc     1260

gccuuccccg gcaucgaaag caaagucgac gcagucuucc aacaagaaca cuucuuccac     1320

guuuucucag gcccucgcua cuacgccuuc gaccuaaucg cccaacgagu cacccgaguc     1380

gcccgaggaa acaaauggcu uaacugccgc uacggauagg gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2383
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt11)

<400>  2383
gggagaaagc uuaccauguc ccucuggcaa ccucucguau uaguacuccu aguccuugga       60

ugcugcuuug ccgcuccucg acaacgccaa uccacacucg uccuuuuccc aggggaucua      120

agaaccaacc uuaccgaccg gcaacuagca gaggaauacc uauaccgcua uggauacaca      180

agagucgccg aaaugagagg agaaucgaaa agccucggac cagcccuccu acuacuacaa      240

aaacaacucu cccugcccga aacuggcgaa cucgacucug ccacucuaaa agcaaugagg      300

accccacgau gcggcguccc cgaccuaggc agauuccaaa ccuucgaagg cgaucuaaaa      360

uggcaccacc acaacauaac cuacuggauc caaaacuacu cagaagaccu cccccgagcc      420

guaauagacg augccuucgc aagagcuuuc gcccucuggu cggcagucac uccccucacc      480

uuuaccagag uauacucccg agacgccgac auagucaucc aauucggcgu cgccgaacac      540

ggcgacggcu accccuucga cggaaaagau ggacuccucg cucacgcguu cccaccaggc      600

ccagguaucc aaggcgaugc ucacuucgac gacgacgaac uauggucucu cggaaaaggg      660

gucgucgucc ccacccgauu cggaaacgca gacggcgccg cuugccacuu ccccuucauc      720

uucgaaggac guuccuacag cgccugcacg accgacggaa gauccgaugg acuaccaugg      780

ugcucaacga ccgccaacua cgacacagac gacagauucg gauucugucc cucagaacgu      840

cucuacacac aagacggcaa cgccgauggc aaacccugcc aauuccccuu cauauuccaa      900

ggccaauccu acuccgccug cacaaccgac ggacgcucug acggcuaccg auggugcgcu      960

acaacagcaa acuaugaucg agacaaguua uuuggauucu gccccacccg cgccgauucc     1020

accguaaugg gugggaacuc cgcaggagaa cucugcgucu uccccuucac cuuccucgga     1080

aaagaguaca gcacaugcac cuccgaaggc cgaggcgacg gccgccuaug gugcgccacc     1140

accuccaacu uugacucaga caagaaaugg gguuucugcc ccgaccaagg uuacagccuc     1200

uuccucgucg ccgcacauga auuuggacac gcauuaggcc uagaccacuc gucagucccc     1260

gaagcccuca uguaccccau guacagauuc acugaaggcc caccccucca caaagacgac     1320

gucaacggaa uccgccaucu cuacggcccc cgaccagaac cugaaccacg cccacccaca     1380

accaccacac cccaacccac cgccccaccc acugucugcc ccaccggccc acccaccguc     1440

caucccagcg agagacccac cgcgggccca accggcccac ccuccgcagg ccccacugga     1500

cccccaaccg caggacccuc caccgcuacu accguuccac uauccccagu cgacgacgcu     1560

ugcaacguca acaucuucga cgccauagcu gagauaggaa accagcucua ccuauucaaa     1620

gacggaaaau acuggcgauu cuccgaggga cgcggcuccc gcccccaagg accauuucua     1680

auagcagaca aguggcccgc acucccacgc aaacuugacu ccguuuucga ggaaagacuc     1740

uccaagaaac uauucuucuu uuccggccga caagucuggg uuuacacagg cgccuccgua     1800

cucgguccuc gccgccuuga caaacuaggg cucggcgcag acgucgccca gguaacagga     1860

gcucuccgaa gcggaagggg caaaauguua cucuucuccg gccgucgacu cuggcgauuc     1920

gacguaaaag cccaaauggu agaucccaga agcgccagcg aagucgaccg cauguuccca     1980

ggaguccccc uugauaccca cgacgucuuc caauaccgcg aaaaagccua cuuuugccaa     2040

gaccgcuucu acuggcgcgu cucuagcaga ucagaacuua accaaguaga ccaaguaggc     2100

uacgucaccu acgacauccu acagugccca gaagacuaag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  2384
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt11)

<400>  2384
gggagaaagc uuaccaugca ccccggcgua cucgcagccu uccuauuccu auccuggacc       60

cacugccgcg cauuaccccu ccccucagga ggcgaugaag acgaccuuuc cgaagaagac      120

cugcaauucg ccgaacgcua ccuccgaucc uacuaccacc ccaccaaccu cgccggcaua      180

cucaaagaaa acgcagccuc auccaugaca gaacgccucc gcgaaaugca auccuucuuu      240

ggccucgaag ucaccggaaa acuugacgac aacacgcuag acgucaugaa aaaacccaga      300

ugcggagucc ccgacgucgg cgaauacaac gucuucccca gaacccuaaa auggucaaaa      360

augaaccuca ccuacagaau agucaacuac accccugaca ugacccacuc cgaaguagaa      420

aaagccuuca aaaaagccuu caaagucugg ucugacguua ccccccucaa cuucacccga      480

cuccacgacg gcaucgccga cauaaugauc uccuucggaa ucaaagaaca cggcgacuuc      540

uaccccuucg acggaccauc aggccuacuc gcccacgccu ucccaccagg acccaacuac      600

ggaggcgacg cccacuucga ugacgacgaa accuggaccu ccuccuccaa aggcuacaac      660

cucuuccuag uagccgcaca cgaauucggc cacucacuag gacuagacca cuccaaagac      720

cccggcgcuc uuauguuccc caucuacacc uacacuggga aaucccacuu caugcucccc      780

gacgacgacg uacaaggcau ccaaagccuc uacggcccgg gcgacgaaga ucccaacccc      840

aaacacccca aaacaccaga caaaugcgac cccucacuau cacuagacgc aaucaccucc      900

cuccguggcg aaacuaugau cuucaaagac cgauucuucu ggcgcuuaca cccccaacaa      960

gucgacgccg aacucuuccu uaccaaauca uucuggcccg aacuccccaa ccgcaucgac     1020

gccgccuacg aacaccccag ccaugaccuc aucuuuaucu uccgcgggag aaaauucugg     1080

gcacuaaacg gauacgacau acucgaaggc uacccaaaaa aaaucuccga acuaggccuc     1140

ccaaaggaag ucaaaaagau cuccgcagca guacacuucg aagacaccgg caaaacccuc     1200

cuauucucag guaaccaagu auggcgcuac gacgacacca accacaucau ggacaaagac     1260

uacccccgcc ucaucgaaga agacuucccc ggcauaggcg acaaagucga cgccgucuau     1320

gaaaaaaacg gcuacauaua cuucuuuaac ggccccaucc aauuugaaua cuccauaugg     1380

uccaaccgca ucguacgcgu uaugccagcc aacuccaucc ucuggugcua aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2385
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt11)

<400>  2385
gggagaaagc uuaccaugga aaccccgaac accaccgaag auuacgacac cacaaccgag       60

uucgacuacg gcgacgccac ccccugccaa aaagucaacg aacgcgccuu cggcgcccaa      120

cuccucccac cccuuuacuc ccucgucuuc gucaucggcc ucgucggcaa uauccucgua      180

guccucgucc ucguccaaua caaacgacuc aaaaacauga ccuccaucua ccuacucaac      240

cuugccaucu ccgaccuccu cuuccucuuc acccuccccu ucuggauaga cuacaaacuc      300

aaagacgacu gggucuucgg cgacgccaug ugcaaaaucc ucucgggcuu cuacuacaca      360

ggacucuacu ccgaaaucuu cuucaucauc cuccuaacua ucgaccgcua ccuagccauc      420

guccacgccg ucuucgcacu acgcgcccgc accguaaccu ucggcgucau caccucaauc      480

aucaucuggg cccucgccau ccucgccucc augcccggcc ucuacuucuc aaaaacccaa      540

ugggaguuca cacaccacac augcucacuc cacuuccccc acgaaucccu acgcgaaugg      600

aaacucuucc aagcccucaa acucaaccua uucggccuag uccucccacu acucgucaug      660

aucaucugcu acacaggcau caucaaaaua cuccuccgcc gccccaacga aaagaaaucc      720

aaagcagucc gccucaucuu ugucauaaug auaaucuucu uccuauucug gacccccuac      780

aaccucacca uccucaucuc aguauuccaa gacuuccucu ucacccauga augcgaacaa      840

ucacgccacu uagaccucgc cguccaaguc accgagguca uugccuacac ccacugcugc      900

gucaacccag uaaucuacgc cuucgucggc gaacgcuucc gcaaauaccu ccgucaacua      960

uuccaccgac gcgucgccgu acaccucguc aaauggcucc ccuuccuauc ugucgaccga     1020

cuagaacgcg ucuccuccac aagcccaagc accggcgaac acgaacucuc cgccggcuuc     1080

uagggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  2386
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt11)

<400>  2386
gggagaaagc uuaccaugcg cacacucgcc ugccuccuac uccucggcug cggcuaccuc       60

gcacacgucc ucgccgaaga agccgaaauc ccccgagaag ucaucgaacg acucgcccgc      120

ucccaaaucc acuccauccg cgaccuccaa cgccuccucg aaaucgacuc cgucggcucc      180

gaagacuccc ucgacaccuc acuccgcgcc cacggagucc acgccaccaa acacguaccc      240

gaaaaacgac cccuccccau ccgccgaaaa cgcuccauag aagaagccgu ccccgccguc      300

ugcaaaaccc gcaccgucau cuacgaaauc ccccgcuccc aagucgaccc cacauccgcc      360

aacuuccuca ucuggccccc cugcguagaa gucaaacgcu gcaccggcug cugcaacaca      420

uccuccguaa aaugccaacc cucccgcgua caccaccgcu ccgucaaagu cgccaaaguc      480

gaauacgucc gcaaaaaacc caaacuaaaa gaaguccagg uccgccucga agaacaccuc      540

gaaugcgccu gcgccaccac cucccucaac ccagacuacc gcgaagaaga caccggccgc      600

ccccgcgaau ccggcaaaaa acgcaaacgc aaacgccuga aacccaccua aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  2387
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt11)

<400>  2387
gggagaaagc uuaccaugaa ccgaugcugg gcccucuucc ucagccucug cugcuaccua       60

cgacuuguau cagccgaagg cgacccaauc ccagaagaac uauacgaaau gcuguccgac      120

cacuccaucc gcuccuucga cgaccuccaa cgccuccucc acggugaccc cggcgaagaa      180

gacggcgccg aacuagaccu uaauaugacc cgcucccacu ccggcggaga acucgaauca      240

cucgcccgcg gacgccgcuc ccuaggcucc cucaccaucg ccgaaccagc caugaucgcc      300

gaaugcaaaa cacgcaccga aguauucgaa aucucacgcc gacucaucga ccgcaccaac      360

gccaacuucc uugucuggcc cccaugcguc gaaguccaac gcugcuccgg cugcugcaac      420

aaccgcaacg uacaaugccg acccacacaa guacaacucc gcccagucca aguacgcaaa      480

aucgaaaucg uccgcaaaaa accaaucuuc aaaaaagcca cagucacccu cgaagaccac      540

cucgccugca aaugcgaaac cguagccgcc gcacgccccg ucacccgcuc acccggcgga      600

ucacaagaac aacgugcaaa aaccccccaa acccgcguca caauccgcac cguccgcguc      660

cgccgccccc ccaaaggaaa acaccgcaaa uucaaacaca cacacgacaa aaccgcccuc      720

aaagaaaccc uaggcgccua aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  2388
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt11)

<400>  2388
gggagaaagc uuaccaugag ccucuucggc cuccuccucc ucaccuccgc ccuggccggc       60

cagcgccaag gcacccaggc cgaauccaac cucuccucca aauuccaauu cuccuccaac      120

aaagaacaaa acggcgucca agacccccaa cacgaacgaa ucaucaccgu cucaacaaac      180

ggcucaauac acucaccacg cuucccccac accuacccaa gaaacaccgu ccucgucugg      240

cgccuagucg ccgucgaaga aaacguaugg auccaacuca ccuucgacga acgcuucggc      300

cucgaagacc cagaagacga caucugcaaa uacgacuucg uagaagucga agaaccuagc      360

gacggcacca uacucggacg uuggugcggc uccggcaccg uccccggcaa acaaaucucc      420

aaaggcaacc aaauccgaau acgcuucgua uccgacgaau acuucccauc cgaacccggc      480

uucugcaucc acuacaacau cgucaugccc caauucaccg aagccgucuc ccccuccgua      540

cuaccccccu ccgcccuccc ccucgaucuu cucaacaacg ccaucacggc cuucuccacc      600

cucgaagacc uaauacgcua ccuggaaccc gaaagauggc aacucgaucu cgaagaucua      660

uaccgcccca cauggcaacu ccucggcaaa gccuucgucu ucggcagaaa aucccggguc      720

guagaccuca accuccucac cgaagaagua cgccuauacu ccugcacacc acgcaacuuc      780

uccguaucca uccgagaaga acucaaacgc accgacacua ucuucuggcc cggcugccuc      840

cucgucaaaa gaugcggcgg aaacugcgcc ugcugucucc acaacugcaa cgaaugccaa      900

ugcguccccu ccaaaguaac caaaaaauac cacgaagucc uacaacuucg cccaaaaacc      960

ggcguaagag gccuccacaa aucccucacc gacgucgcac uagaacacca cgaagaaugc     1020

gacugcgucu gccgcggcuc caccggagga uaaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  2389
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt11)

<400>  2389
gggagaaagc uuaccaugca ccgccuaauc uucgucuaca cccuaaucug cgccaacuuc       60

ugcuccugcc gagacaccuc cgccacccca caauccgccu ccauaaaagc acuccggaau      120

gccaacuuac gccgggacga ccuauaccgu cgagacgaaa caauccaagu aaaaggaaac      180

ggcuacgugc aaucgccccg auucccaaac uccuacccac gcaaccuccu ccucaccugg      240

cgacuacacu cccaagaaaa cacucgcauc caacucgucu ucgacaacca guucggccug      300

gaagaagccg aaaacgacau cugccgcuac gacuucgucg aagucgaaga cauaucagaa      360

accuccacca ucauacgcgg ccgcuggugc ggccacaaag agguaccccc ccgcaucaaa      420

ucccgcacaa accaaaucaa aauaaccuuc aaaucagacg acuacuucgu agcuaaaccc      480

ggauucaaaa ucuacuacuc ccuccuagaa gacuuccaac ccgccgcagc auccgagacc      540

aacugggaau ccguaaccuc cuccauaucc ggcguauccu acaacagccc cuccgucaca      600

gaccccaccc uuauagccga cgcccucgac aaaaaaaucg ccgaauucga caccgucgaa      660

gaucuccuaa aauacuucaa ccccgaauca uggcaagaag accucgaaaa cauguaccua      720

gacaccccac gauaccgcgg acgcucauac cacgaccgaa aauccaaagu cgaccucgac      780

cgacucaacg acgacgccaa acgcuacagc ugcacaccac gcaacuacuc cgucaacauc      840

cgcgaagagc uaaaacucgc caacguaguc uucuuccccc gcugccuucu cguccaaaga      900

ugcggcggca acugcggcug uggaaccgua aacuggcgca gcugcaccug caacucaggc      960

aaaaccguca aaaaauacca cgaaguccuc caauucgaac caggccacau caaacgccgc     1020

ggccgagcca aaacaauggc ccucgucgac auccagcucg accaccacga acgcugcgac     1080

ugcauaugcu ccagccgccc cccucgcuaa ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  2390
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt11)

<400>  2390
gggagaaagc uuaccauggu cacccacucc aaauucccug ccgcaggcau gucccgaccc       60

cucgacaccu cccuccgacu caaaaccuuc uccucaaagu ccgaauacca acucgucguc      120

aacgccgucc guaaacucca agaauccggc uucuacuggu ccgccgucac cgguggugaa      180

gcaaaccucc uccucuccgc agaacccgcc ggcaccuucc ucauccgcga cuccucagac      240

caacgccacu ucuucacccu cucagucaaa acccaauccg gcaccaaaaa ccuccgcauc      300

caaugcgaag gcggcuccuu cucccuccaa uccgacccac gcuccacaca accuguccca      360

cgcuucgacu gcguccucaa acucguccac cacuacaugc caccccccgg cgcccccucc      420

uucccauccc cccccaccga acccuccuca gaaguccccg aacaacccuc agcccaaccc      480

cuccccggcu cccccccccg ccgcgcauac uacaucuacu ccggcggcga aaaaauccca      540

cucguacucu cccgcccccu cuccuccaac gucgccaccc uacaacaccu cugccgcaaa      600

accgucaacg gccaccucga cuccuacgaa aaagucaccc aacuacccgg ccccauccgc      660

gaauuccucg accaauacga ugcaccccua uaaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  2391
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt11)

<400>  2391
gggagaaagc uuaccauggu ccccuccgcc ggccaacucg cccuauucgc ccucggaauc       60

guccucgcag ccugccaagc ccucgaaaac uccaccuccc cccucuccgc cgaccccccc      120

gucgccgccg ccgucgucuc ccacuucaac gacugccccg acucccacac ccaauucugc      180

uuccacggca ccugccgcuu ccucguccaa gaagacaaac ccgccugcgu cugccacucc      240

ggcuacgucg gcgcccgcug cgaacacgcc gaccuccucg ccgucgucgc cgccucccaa      300

aaaaaacaag ccaucaccgc ccucgucguc gucuccaucg ucgcccucgc cguccucauc      360

aucaccugcg uccuaaucca cugcugccaa guccgcaaac acugcgaaug gugccgcgcc      420

cucaucugcc gccacgaaaa acccuccgcc cuccucaaag gccgcaccgc cugcugccac      480

uccgaaacag ucguuuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  2392
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt11)

<400>  2392
gggagaaagc uuaccaugcc ucccucuggc cuucgacugc ucccccuccu ccucccccuc       60

cuauggcucc uaguccuaac acccggccgc ccagccgcag gccucuccac augcaaaaca      120

auagacaugg aacucgucaa acgaaaacgc aucgaagcaa uccgcggcca aauacucucu      180

aaacuucgcc ucgccucacc acccucccaa ggcgaagucc caccaggacc ccuccccgaa      240

gccguauuag cucucuacaa cuccacacgc gaccgcgucg caggcgagag cgccgaaccc      300

gaacccgaac cugaagcuga cuacuacgcc aaagaaguaa cacgcguccu caugguugaa      360

acccacaacg aaaucuauga caaauucaaa caauccaccc acucaaucua cauguucuuu      420

aacacaucag aacuccgcga agccgucccc gaaccagucc uccuuucccg ugccgaacuc      480

cgccuacugc gccucaaacu aaaaguagaa caacacguug aacucuacca aaaauacuca      540

aacaauuccu ggcgauaccu cuccaaccgc cuccucgccc ccuccgacag ccccgaaugg      600

cucucuuuug acgucacagg cgucguacgc caauggcucu caagaggcgg cgaaaucgaa      660

ggcuuccgcc ucucagccca uugcucuugc gacucucgcg acaacacccu ccaagucgac      720

aucaacggcu ucaccaccgg ccgacgcggc gaccucgcca ccauccacgg caugaaccgu      780

ccuuuccuac uucuaauggc cacaccccuc gaacgcgccc aacaccucca aucaucacgc      840

cacagacgcg cccucgacac caacuacugc uucuccucca ccgaaaagaa cugcugcgua      900

cgccaacucu acaucgacuu ccguaaagac cucggcugga aauggaucca cgaacccaaa      960

ggcuaccacg ccaacuucug ucuuggccca ugccccuaca ucuggucccu agacacucaa     1020

uacuccaaag uccuagcccu uuacaaccaa cacaaccccg gcgcaucagc cgcccccugc     1080

ugcguacccc aagcccucga accacucccc auagucuacu acguaggccg aaaacccaaa     1140

gucgagcaac uauccaacau gaucguccgg ucgugcaaau gcuccuaagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  2393
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt11)

<400>  2393
gggagaaagc uuaccaugca cuacugcguc cucuccgccu uccucauauu acaccucguc       60

accguugccc uaucccucuc gacuugcucc acccucgaca uggaccaauu caugcgcaaa      120

agaaucgaag caauccgagg ccaaauccuc ucaaaacuca aacuuacauc ccccccugaa      180

gacuauccag aacccgagga aguccccccu gaagucauau ccauauacaa cagcacccgc      240

gaccuacucc aagaaaaagc cucgcgacga gccgcagccu gcgaacgcga acgcagcgac      300

gaagaauacu acgccaagga agucuacaaa aucgacaugc cgcccuucuu cccaucagag      360

aaugcuaucc cccccaccuu cuaccgacca uacuuccgca ucguccgcuu cgacgucucc      420

gcaauggaaa aaaacgccuc caaccucguc aaagccgaau uccgcgucuu ccgccugcaa      480

aaccccaaag cccgcguucc cgaacaacgc aucgaacucu accaaauacu caaauccaaa      540

gaccucaccu cucccaccca acguuacauc gacucuaaag uagucaaaac acgcgccgaa      600

ggcgaauggc ucuccuucga cguaaccgac gccguacacg aauggcucca ccacaaagac      660

agaaaccucg gauucaaaau cucccuacac ugccccugcu gcacuuucgu ccccuccaac      720

aacuacauaa uucccaacaa auccgaagag cuugaagccc gcuucgccgg caucgacgga      780

accucgaccu acacuucagg cgaccagaaa accauuaaau ccacccgcaa aaaaaacucg      840

ggcaaaacac cccaccuccu acucaugcuc cucccauccu accggcuaga aucccaacaa      900

accaaccgac gcaaaaaacg agcccucgac gcagccuacu gcuuccguaa cguccaagac      960

aauugcugcc uacgcccacu cuacaucgau uucaaacgug accucggaug gaaauggauc     1020

caugaaccca aaggcuacaa cgccaacuuc ugcgcaggcg caugccccua ccucuggagc     1080

uccgacaccc aacacucccg cguccuaagc cuuuacaaca ccaucaaccc cgaagccuca     1140

gccucccccu gcugcgucuc ccaagaccuc gaaccacuaa caauccucua cuacaucggc     1200

aaaaccccca aaauagaaca acucuccaac augaucguca aauccugcaa augcuccuaa     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  2394
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt11)

<400>  2394
gggagaaagc uuaccaugaa aaugcaccuc caacgagccc uagucguccu cgcacuacuc       60

aacuucgcaa ccgucucccu aagccuuucc acaugcacca cccuggacuu cggccacauc      120

aaaaagaaac gugucgaagc cauucgaggc caaauacuca gcaaacuccg ccucacauca      180

cccccagaac ccacaguuau gacccacguc cccuaccagg uccuagcccu auacaacagc      240

acccgcgaac uccucgaaga aaugcacggc gaacgcgaag aaggcugcac ccaagaaaau      300

acagaguccg aauauuaugc aaaagaaauc cacaaauucg acaugaucca gggccucgcc      360

gaacacaacg agcucgccgu cugucccaaa ggcaucaccu ccaaaguauu cagauucaac      420

gugucauccg ucgagaaaaa ccgcaccaac cucuuccgcg ccgaguuccg uguccuccgc      480

gucccaaacc ccuccagcaa acgaaacgaa caacgaauag aacuauucca gauccuccgc      540

cccgacgaac acaucgccaa acaacgcuac auugggggca aaaaccuccc cacccgcgga      600

acagccgaau ggcuauccuu cgacgucacc gacaccgucc gcgaauggcu acuaagaaga      660

gaauccaacc ucggccucga aaucuccaua cacugccccu gccacaccuu ccaacccaac      720

ggagacauac ucgaaaacau ccacgaagua auggaaauca aguucaaagg agucgacaac      780

gaagacgacc acggccgcgg cgaccuaggc cgccucaaaa agcagaaaga ccaccacaac      840

ccccaccuaa uacuaaugau gauacccccu caccgccucg acaaccccgg ccaaggcgga      900

caacgcaaaa agcgcgcccu cgacacuaac uacugcuucc gcaaccucga agaaaacugc      960

ugcguccgcc cccucuacau cgacuuccgc caagaccucg gguggaaaug gguacacgaa     1020

cccaaaggcu acuacgccaa cuucugcagc ggaccaugcc cauaccucag aagcgcagac     1080

acaacacacu ccaccguccu cggccucuac aacacccuaa accccgaagc cucagccucc     1140

cccugcugcg uaccacaaga ccuugaacca cucaccaucc ucuauuacgu aggccgcacc     1200

cccaaagucg aacaacucuc aaacaugguc guaaaaucau gcaaaugcuc cuaaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2395
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt11)

<400>  2395
gggagaaagc uuaccauggc accagucgca gucugggccg cccucgccgu aggccuugaa       60

cucugggcag ccgcccacgc ccucccagca caagucgcau ucacucccua cgcacccgaa      120

cccggcucca ccugccgccu acgcgaauac uaugaccaaa cagcacaaau gugcugcucc      180

aaaugcucuc ccggccaaca cgcuaaagua uucugcacaa aaaccucuga caccguaugc      240

gacucaugcg aagacuccac auauacccaa cucuggaacu ggguccccga augccucucc      300

ugcggcuccc gcugcagcuc agaccaagua gaaacccaag cuugcacccg cgagcaaaac      360

cgcaucugca caugccgccc cggcugguac ugcgcucucu ccaaacaaga aggcugcaga      420

cuuugugcac cucugaggaa augccgacca ggcuuuggug uagcaagacc cgguaccgaa      480

accucagacg ucgucugcaa accgugugca cccggcaccu ucucaaacac caccuccucu      540

accgacaucu gccgaccaca ucaaaucugc aacguagucg ccaucccagg caacgccucc      600

auggacgccg uaugcaccuc gaccuccccc acccgcucca uggcccccgg cgccguacac      660

cuaccccaac ccgucuccac ccgaucccag cacacccaac ccaccccaga acccagcacc      720

gccccgucaa ccucauuccu acucccaaug ggccccuccc cacccgcaga aggcuccaca      780

ggcgauuucg cccuccccgu aggacuaaua guuggcguca ccgcccuagg ccuccuuauc      840

aucggcguag ucaacugcgu caucaugacc caagucaaaa aaaaaccccu cugccuccaa      900

cgcgaagcca aagucccaca ccucccagcc gacaaagccc gcggaaccca aggccccgaa      960

caacaacacc ugcucaucac cgcccccuca ucaagcuccu ccucacucga aucauccgcc     1020

uccgcccucg aucgacgcgc ccccacacgc aaccaaccac aagccccagg cguagaagcg     1080

uccggcgccg gcgaagcccg cgccuccacc ggcucguccg acuccucacc aggaggucac     1140

ggcacccaag uaaaugucac cugcaucgug aacguuuguu ccuccucaga ucacagcucc     1200

caaugcucuu cccaagccuc cuccacaaug ggcgacaccg auuccagccc cucagaaucc     1260

cccaaagacg aacaaguccc auucucaaaa gaagagugug ccuuccgauc ccagcucgaa     1320

acaccagaaa cccuacucgg uucaaccgaa gaaaaacccc ucccccucgg cgucccagac     1380

gcaggcauga aacccuccua aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  2396
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt11)

<400>  2396
gggagaaagc uuaccaugcc ggucaugcgc cuguucccgu gcuuucucca gcuacuggcc       60

gggcucgcgc ucccggccgu gcccccgcaa caaugggcgc ucucggccgg aaacgggagc      120

ucggaagugg aagugguccc guuccaggaa gugugggggc gcucguacug ucgagcgcuc      180

gagcgcuugg ucgaugucgu gagcgaguac ccgagcgagg ucgagcacau guucucgccc      240

ucgugcguga gcuugcuaag gugcacggga uguugcgggg acgagaacuu gcacugugua      300

ccggucgaga ccgcgaacgu gaccaugcaa uugcucaaga ucaggagcgg ggacaggccc      360

ucguacgugg aauugaccuu uagccagcac gugcgcugug aaugucgccc gcucagggaa      420

aagaugaagc cagagcgcag gcgcccgaaa gggcgaggga aaaggcgcag ggaaaagcaa      480

agacccacgg acugucacuu gugcggggac gcggucccga ggcgcugagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  2397
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt11)

<400>  2397
gggagaaagc uuaccaugac cgauagacag accgacacag cgcccucacc cucguaccau       60

cucuugccgg ggaggaggag aacgguagac gcggcggcau cgcgcgggca agggccggaa      120

ccagcgccag ggggaggagu cgaaggagug ggagcgagag gggucgcgcu aaaacucuuc      180

guccaacugc ugggaugcag cagguucggg ggagcagugg uaagagcagg agaggcagag      240

ccaucgggcg cggcaaggag cgcaagcucg ggaagggagg aaccacagcc agaagaaggg      300

gaagaggaag aggaaaagga agaagaaagg ggaccacaau ggagacuagg cgcgagaaag      360

ccagggagcu ggacagggga ggcggccgug ugcgcggacu cggcaccagc cgcaagagcg      420

ccgcaggcac uagcaagggc cucgggaagg ggaggaaggg uggcaagacg aggagccgag      480

gaaucaggac caccacacag cccaagcagg cgagggagcg cgagcagggc agggcccggg      540

agagcaagcg agacaaugaa cuuucucuug agcuggguac auuggucgcu agcgcuccua      600

cuguaucugc accacgcgaa auggagccag gcagcgccaa uggcagaggg aggagggcag      660

aaccaccacg aagucgugaa auucauggau guauaccaaa ggagcuacug ccacccaaua      720

gaaacgcuag uagacauauu ccaggaauau ccagaugaaa uugaauacau auucaaaccg      780

agcugcguac cacucaugag guguggcgga ugcuguaacg augaagggcu agagugcgug      840

ccaacagaag agagcaacau aacaaugcaa auaaugcgaa uaaaaccaca ccaaggacag      900

cacauaggag agaugagcuu ccuacaacac aacaagugcg agugcaggcc aaagaaagac      960

agagcgcgcc aagaaaagaa aagcguaagg ggaaagggga agggacagaa aaggaaaagg     1020

aaaaagagua gauacaaaag uuggagcgua uacguaggag cgagaugcug cuugaugccg     1080

uggucacuac cgggaccaca cccguguggg cccugcagcg agagacgaaa acaccuauuc     1140

gugcaggacc cgcagacgug caagugcucg uguaagaaca cggacucgag gugcaaagcg     1200

agacagcuag agcugaauga aaggaccugc cgaugugaca agcccagaag guagggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2398
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt11)

<400>  2398
gggagaaagc uuaccaugaa cuuccuccua agcugggucc acuggucccu cgcccuacuc       60

cucuaccuac accacgccaa auggucccaa gccgcaccca uggccgaagg cggcggccaa      120

aaccaccacg aagucgucaa auucauggac gucuaccaac gcucauacug ccaccccauc      180

gaaacccucg ucgacaucuu ccaagaauac cccgacgaaa uagaauacau cuucaaaccc      240

ucaugcgucc cccucaugcg cugcggcggc ugcugcaacg acgaaggacu cgaaugcgua      300

cccaccgaag aaucaaacau cacaaugcaa aucaugcgca ucaaacccca ccaaggccaa      360

cacaucggcg aaauguccuu ccuccaacac aacaaaugcg aaugccgccc caaaaaagac      420

cgagcacgac aagaaaaaaa auccguccga ggcaaaggca aaggccaaaa acgaaaaaga      480

aaaaaauccc gcuacaaauc cugguccgua uacgucggcg cccgaugcug ccucaugcca      540

uggucccucc ccggccccca cccaugcggc cccugcuccg aacgccgcaa acaccucuuc      600

guccaagacc cccaaaccug caaaugcucc ugcaaaaaca ccgacuccag augcaaagcc      660

cgccaacucg aacucaacga acgcaccugc cgcugcgaca aaccccgacg cuaaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  2399
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt11)

<400>  2399
gggagaaagc uuaccauguc cccccuccuc cgccgccucc uccucgcagc ccuacuccaa       60

cuagcccccg cacaagcccc cgucucccaa cccgacgccc ccggccacca acgcaaagua      120

gucuccugga uagacgucua cacccgcgcc accugccaac cccgcgaagu cguagucccc      180

cucacagucg aacucauggg cacagucgcc aaacaacucg uacccucaug cgucaccguc      240

caaagaugcg gcggcugcug ccccgacgac ggccucgaau gcguccccac cggccaacac      300

caaguccgca ugcaaauacu caugauccga uacccaucau cccaacuagg agaaauguca      360

cucgaagaac acucucaaug cgaaugcaga cccaaaaaaa aagacucagc cguaaaacca      420

gaccgcgccg caacacccca ccaccgcccc caaccacgau caguccccgg cugggacucc      480

gcccccggcg cccccucccc cgccgacauc acccacccca cccccgcccc cggcccaucc      540

gcccacgccg cccccuccac caccucugcc cuaacccccg gccccgccgc cgccgccgca      600

gacgccgccg ccucauccgu cgccaaaggc ggcgccuaag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  2400
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt11)

<400>  2400
gggagaaagc uuaccaugca ccuccuaggc uucuucagcg uugccugcuc ccuacuggcc       60

gccgcccucc ucccuggccc ccgcgaagcu cccgcagccg cagcagccuu ugaaucaggu      120

cucgaccuua gcgacgcaga acccgacgcc ggagaagcua ccgccuacgc gagcaaagac      180

cucgaagaac aacugcgauc cgucuccucc gucgacgaac ucaugacugu acucuacccc      240

gaauacugga aaauguacaa augccaacuc cggaaaggag gcuggcaaca caacagagaa      300

caagccaacc ucaacucccg aaccgaagaa acuaucaaau ucgccgcagc ccacuacaac      360

accgaaauac ucaaaucaau cgacaacgaa uggagaaaaa cccaaugcau gccccgagaa      420

gucugcaucg acgucggcaa agaguucgga gucgccacca acacauucuu caaaccaccu      480

uguguauccg ucuaccgaug cggagguugc ugcaacuccg aaggccuaca augcaugaac      540

accuccaccu cauaccucuc aaaaacacuc uucgaaauca ccgucccccu aagccaaggc      600

ccgaaaccag ucaccauuuc cuucgcaaac cauacaucau gccgauguau gucaaaacuc      660

gacgucuacc gccaagucca cuccauaauc cgacgcucac ucccagccac ccucccccaa      720

ugccaagcag caaacaaaac cugcccaacc aacuacaugu ggaacaacca caucugccgc      780

ugccucgcac aagaagacuu cauguucagc uccgacgccg gcgacgacuc caccgacggc      840

uuccacgaca ucugcggccc caacaaagaa cucgacgaag aaacaugcca augcguuugu      900

cgcgccggcc uccgcccagc cuccugcgga ccacacaaag aacucgacag aaacuccugc      960

caaugcguuu gcaaaaacaa acuauuccca ucccaaugcg gagccaaccg cgaguucgac     1020

gaaaauaccu gccaaugcgu augcaaacga accugccccc gaaaccaacc ccuaaacccc     1080

ggcaaaugcg cuugcgaaug caccgaaucc ccgcaaaaau gccuccucaa aggaaagaaa     1140

uuccaccacc aaaccugcuc cugcuaccgc cgacccugca ccaaccguca aaaagcgugc     1200

gaacccggau ucuccuacuc cgaagaaguc ugccgcugcg uccccagcua cuggaaacgc     1260

ccccaaaugu ccuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  2401
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt11)

<400>  2401
gggagaaagc uuaccaugua ccgagaaugg gucgucguca acguauucau gaugcucuac       60

guacaacucg uccaaggcag cagcaacgaa cacggccccg ucaagagauc cagccaaagc      120

acccuagaac gauccgaaca acaaauacgc gcagccucaa gccucgaaga guuacuacga      180

aucacccacu cagaagacug gaagcucugg cgaugccgcc uccgccucaa guccuucacc      240

uccauggaca gcagaucagc cucccaccgc ucaacccguu ucgccgccac cuucuacgac      300

aucgaaaccc ucaaagucau cgacgaggaa uggcaacgaa cacaaugcuc ucccagagaa      360

accugcguag aagucgccuc cgaacuuggu aaaucaacca acacuuucuu caaaccaccc      420

ugcgucaacg ucuuccgcug cggaggcugc ugcaacgaag agucccucau augcaugaac      480

acauccaccu ccuacaucuc caaacaacuc uucgaaauau ccguaccccu aaccuccguc      540

ccagaacuug uacccgucaa agucgccaac cacaccggcu gcaaaugccu ccccacagca      600

ccccgccacc ccuacuccau aauccgccga ucgauacaaa uaccggaaga agaccgcugc      660

ucacacucaa agaaacucug ccccauagac augcucuggg acuccaacaa augcaaaugc      720

guccuccagg aagaaaaccc ccuagccggc acagaagacc acucccaccu ccaagaacca      780

gcccucugcg gcccccauau gauguucgac gaagaccgcu gcgaaugcgu augcaaaacc      840

cccugcccca aagaccucau ccaacacccc aaaaacugcu caugcuucga augcaaagaa      900

ucacucgaaa ccugcugcca aaaacacaaa cucuuccacc ccgacacaug cucaugcgaa      960

gaccgaugcc ccuuccacac ccgccccugc gccuccggca aaaccgccug cgccaaacac     1020

ugccgauucc caaaagaaaa acgcgccgcc caaggccccc acucacgcaa aaauccauaa     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  2402
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt12)

<400>  2402
gggagaaagc uuaccaugga uuccgacgaa accggcuuug aacacucagg auuaugggua       60

ucaguauuag caggacuacu acuaggagca ugccaagcac acccaauacc agacucauca      120

ccauuauuac aauucggagg acaaguaaga caaagauacc uauacacaga cgacgcucaa      180

caaacagaag cacauuuaga aauaagagaa gacggaacag uaggaggcgc agccgaccaa      240

ucaccagaau cuuuacuaca auuaaaagca cuaaaaccag gcguaauaca aauauuagga      300

guaaaaacau caagauucuu augccaaaga ccagauggag cacuauacgg aucacuacac      360

uuugacccag aagcaugcuc auucagagaa uuacuauuag aagacggaua uaacguauac      420

caaucagaag cacauggacu accccuacac cuaccaggaa acaaaucacc acaucgagac      480

ccagccccaa gaggccccgc aagauuccua ccacuaccag gacuaccacc agcacuacca      540

gaaccaccag gaauauuagc accacaacca ccagauguag gauccuccga cccauuauca      600

augguaggac caucacaagg aagaucucca ucauacgcau cauaaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  2403
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt12)

<400>  2403
gggagaaagc uuaccaugca uucauuccca ccucuauuac uacuauuauu uugggguguu       60

guaucccacu cauuuccagc uacauuagaa acacaagaac aagacguaga ucuaguccaa      120

aaauaucuag aaaaauacua caaccuaaaa aacgacggac gccaaguaga aaaaagaaga      180

aacaguggac caguaguaga aaaacuaaaa caaaugcaag aauuuuuugg acuaaaaguc      240

acaggaaaac cugaugccga aacuuuaaaa guaaugaaac aaccaagaug cggcguaccu      300

gacguagcac aauucgucuu aacagaagga aacccaagau gggaacaaac gcacuuaaca      360

uaucgaaucg aaaauuacac accagaccua ccaagagcag acguagauca cgcaauagaa      420

aaagccuucc aacuaugguc aaauguaaca ccccuaacau ucacaaaagu aucagaagga      480

caagcagaua uaaugaucuc auucguaaga ggggaucaca gagauaacuc acccuucgau      540

ggcccaggag gaaaccuagc acacgcauuc caaccuggac caggaauagg uggugaugca      600

cauuucgacg aagacgaaag auggacaaac aacuucagag aauauaaccu acacagagua      660

gcagcucacg aacuagguca uucauuagga cuaagucauu caacagauau aggagcacua      720

auguacccau cauacacuuu uagcggagac guacaacuag cacaagacga cauagaugga      780

auacaagcaa uauacggaag aucacaaaac cccguacaac caauaggacc acaaacacca      840

aaagcaugug acucaaaacu caccuucgac gcaauaacaa ccauaagagg agaaguuaug      900

uucuuuaaag acagauucua caugagaaca aaucccuuuu acccagaagu agaauuaaac      960

uucaucucag uauuuuggcc ccaacuacca aauggucuag aagcagccua cgaauuugcu     1020

gauagagaug aaguaagauu cuucaaagga aacaaauauu gggccgucca aggacaaaac     1080

guauuacacg gauauccaaa agauaucuac uccucauucg gcuuuccaag aacaguaaaa     1140

cauauugaug cagcacuauc cgaagaaaac acaggaaaaa cauacuucuu uguagccaac     1200

aaauacugga gauaugauga auacaaaaga ucgauggacc caggauaccc caaaaugaua     1260

gcacacgacu uuccaggaau aggacacaaa guagaugcag uauucaugaa agacggauuc     1320

uucuacuucu uccacggcac cagacaauac aaauuugacc ccaaaacaaa acgcauccua     1380

acauuacaaa aagcaaauuc augguuuaac uguagaaaaa acuaaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  2404
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt12)

<400>  2404
gggagaaagc uuaccaugca cucauuccca ccacuauuau uacuacuauu cuggggagua       60

guaucacacu ccuucguauu aacugaagga aauccucgau gggaacaaac ccaccucaca      120

uauagaauag aaaacuacac accagaccua ccuagagcag acguagacca cgcaauagaa      180

aaagccuucc aauuaugguc caacgucaca ccauuaacuu ucacuaaagu cucagaagga      240

caagcagaua uaaugauauc cuuugucaga ggagaucaca gagacaacuc accauuugac      300

ggaccaggag gaaaucuagc acacgcauuc caacccggac ccggaauagg uggagacgca      360

cacuucgaug aagaugaaag auggacaaac aauuucagag aauacaauuu acacagagua      420

gcagcacacg aacucggaca cuccuuagga cucucccauu caaccgacau aggagcauua      480

auguacccau cauacacauu cucaggagac guccaacuag cacaagacga uaucgacggc      540

auacaagcua uauacggaag aucacaaaac ccaguacaac caaucggacc acaaacacca      600

aaagccugug acucaaaauu aacuuuugau gcaaucacaa cuauacgagg cgaaguaaug      660

uuuuucaaag acagauucua caugagaaca aaccccuuuu acccugaagu agaacuaaac      720

uucauaucug uuuucuggcc acaacuacca aacggauuag aagcagcaua cgaauuugcc      780

gacagagacg aaguuagauu cuucaaagga aacaaauacu gggcaguuca aggacaaaac      840

gucuuacacg gauauccaaa agauauauac uccucauucg gauucccaag aaccguaaaa      900

cacaucgaug ccgcauuauc agaagaaaau acaggcaaaa cauacuucuu uguugcaaac      960

aaauauugga gauacgacga auacaaacgc ucuauggacc caggcuaucc aaaaaugauu     1020

gcacacgauu ucccaggaau aggacacaaa guagaugcag uauucaugaa agacggauuc     1080

uuuuauuucu uccacggaac aagacaauac aaauucgauc caaaaacaaa aagaauccua     1140

accuuacaaa aagccaacuc augguucaau ugcagaaaaa auuaaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  2405
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt12)

<400>  2405
gggagaaagc uuaccaugaa gaaaaacaua cugaaaaucu uaauggacuc cuacuccaaa       60

gaaucaaaaa uccaaacagu aagacgugua acaucaguau cacuccuggc aguauaccuu      120

acaaugaaca cuucuuccuu aguauuagcc aaaccaauag agaauacuaa ugacacauca      180

aucaaaaaug uagaaaaauu acgaaaugca cccaacgaag aaaacagcaa gaaaguagaa      240

gauuccaaaa acgacaaagu agaacauguu aaaaacauag aagaagcuaa aguagaacaa      300

guugcuccgg aagugaaauc aaaaucaacg uugagaagug caaguauagc aaacaccaac      360

uccgaaaaau augacuucga auacuuaaau ggacuaucgu acacagaauu aacaaauuua      420

auuaaaaaca uaaaauggaa ucaaauaaau ggucuguuca acuauaguac cggcucccaa      480

aaauucuucg gagauaaaaa ucguguucaa gcuauaauaa augcacuaca agaaucuggu      540

agaacauaua ccgcuaacga uaugaaagga auagagacuu uuacggaagu ccuaagagcc      600

ggauucuacu uaggauacua uaacgauggu uuaaguuauu uaaaugacag aaauuuucaa      660

gacaaaugca uaccggcaau gauagcaaua cagaaaaacc cuaacuuuaa gcuaggaaca      720

gcuguccaag acgaaguaau uacaucacua gguaaacuua ucggaaaugc aagcgcaaac      780

gcagaagucg uaaauaauug ugucccagua cuaaaacaau uuagagaaaa uuuaaaccaa      840

uaugcuccag acuauguaaa aggaacagca guaaaugaac uuauaaaagg uauagaguuc      900

gacuucucag gagcagcaua ugaaaaagac guaaaaacaa ugccauggua uggaaaaauc      960

gauccauuua uaaaugaauu gaaggcauua ggccuauaug gaaauauaac cagcgcgaca     1020

gaaugggcau cagacgucgg aauuuacuac cuuaguaaau ucggacuaua uagcacaaau     1080

agaaaugaca uaguacaaag ccucgaaaaa gcgguagaua uguacaaaua uggaaaaaua     1140

gcuuucguag ccauggaacg aauaacaugg gacuaugaug guauagguuc aaacggaaag     1200

aaagucgacc acgauaaauu ccuagacgau gcugaaaaac acuacuuacc aaaaaccuac     1260

acguucgaua auggaacuuu uauaauacgu gcuggagaca aaguuucaga agagaaaauc     1320

aaaagauuau auugggcuuc gcgagaagua aaaucucaau uccaccgagu aguaggaaac     1380

gauaaagcau uagaaguugg aaaugcggac gauguauuaa caaugaaaau uuucaacuca     1440

cccgaagaau auaaauuuaa uacuaacauu aacgguguaa gcacagauaa cggagguuua     1500

uacauagaac cucgaggaac auuuuauacg uaugaacgaa caccacaaca aagcauauuu     1560

ucguuagaag aacuauuuag acaugaauau acacauuacc uacaagcacg auacuuagua     1620

gauggauuau ggggucaagg acccuuuuac gaaaagaauc gccucacaug guucgaugaa     1680

ggcaccgcug aguucuuugc uggcucgacg agaacaagug gagugcuccc aagaaaaagu     1740

aucuuaggau accuugcaaa agauaagguu gaccaucguu auucacuaaa gaaaacuuua     1800

aauucagguu acgacgacag ugauuggaug uuuuacaauu acggauuugc aguagcacau     1860

uaucucuacg aaaaagacau gcccaccuuu auaaaaauga auaaagcaau uuuaaacacc     1920

gauguaaaau ccuacgauga aauaauuaag aaacugagug augacgccaa caaaaauacc     1980

gaauaucaaa aucacaucca agaauuagcc gacaaauacc aaggagcagg uauaccgcua     2040

gugagugaug acuaucucaa agaccacggc uauaagaaag caucugaagu uuacuccgaa     2100

auuagcaaag cggcaucacu caccaauacu agcgucaccg cagaaaaauc ccaauacuuu     2160

aauacauuua cucuucgagg cacauacaca ggagaaacga gcaaaggaga auuuaaagac     2220

ugggacgaaa ugaguaagaa acucgaugga acauuagaau cauuagccaa aaacuccugg     2280

aguggcuaca aaacacuuac ugcauacuuc acaaauuaua gaguaacaag ugauaauaaa     2340

guacaauaug auguagucuu ucacggugua uuaacagaua augcagauau aucaaacaac     2400

aaagcaccaa uagcaaaagu aacuggacca ucaacagggg cugucgggag aaauauugag     2460

uucucaggca aagauucaaa agacgaagau gguaaaauug uuucguacga uugggauuuu     2520

ggcgacggag caacaagucg ugguaaaaac aguguacaug ccuacaagaa agccggaacc     2580

uacaauguaa cauuaaaagu aaccgacgac aaaggagcaa ccgccacaga aaguuuuacu     2640

auagaaauua aaaaugaaga cacaacaacc cccauaacua aagaaaugga accaaacgac     2700

gacauaaaag aagcaaaugg accgaucgua gaaggaguua ccguuaaagg agacuuaaac     2760

ggcucagaug acgcagauac uuuuuacuuc gaugucaaag aagacggaga ugucacaaua     2820

gaauuacccu acaguggauc uucaaacuuu accuggcuag ucuauaaaga aggagaugac     2880

caaaaucaua uagcaagcgg aauagauaaa aacaacagca aaguaggcac auucaaaagu     2940

acaaaaggca ggcauuacgu auuuauauac aaacacgauu cugccucaaa cauuucuuac     3000

aguuuaaaua uuaaaggucu aggaaaugaa aaacuaaaag aaaaagaaaa caacgacuca     3060

ucugacaaag caacaguaau accuaacuuc aacacaacaa ugcaaggauc auuacuagga     3120

gaugacagua gagauuacua uucauuugaa guaaaagaag aaggugaagu aaauaucgag     3180

cuagauaaga aagacgaauu uggagugaca uggacccuuc acccagaauc aaauauaaac     3240

gaucgaauaa cauauggaca agucgauggc aacaaaguau caaauaaagu uaaauuaaga     3300

ccaggaaaau auuaucuccu uguauacaag uauucaggca guggaaacua ugaauugaga     3360

guaaacaaau gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  2406
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt12)

<400>  2406
gggagaaagc uuaccaugaa augggucaca uuuauuucac uacuguuuuu auucucauca       60

gcauauagua uagcaaauac aaacagugaa aaauacgauu ucgaauaucu caacggauug      120

ucauauacag aacuuaccaa ccuuauuaaa aauauaaaau ggaaccaaau aaauggucua      180

uuuaauuaca guacggguuc gcagaaauuc uuuggagaua aaaaccgugu acaggccaua      240

auaaacgcac uacaggaauc cggacgcacc uauacggcua augauaugaa aggaauagaa      300

acuuuuacug aaguacuaag agccggauuu uaucucggau auuacaauga uggauugagu      360

uaccuaaacg auaggaacuu ucaagacaaa uguauuccag caaugauagc aauacagaaa      420

aaccccaacu ucaaauuagg cacagccgua caagacgaag uuauaacuuc auuaggaaaa      480

uuaaucggua acgcaagcgc aaacgccgaa guaguaaaua auuguguacc aguacuaaaa      540

caauucagag aaaaccucaa ccaauacgca cccgauuacg uaaaagggac agcaguaaau      600

gaauuaauaa aagguaucga auuugacuuc uccggagcag cuuaugaaaa agacguuaaa      660

acuaugcccu gguacggaaa aauagauccu uuuauaaaug aacucaaagc auuaggacuc      720

uaugggaaua uaacaucggc uacugaaugg gccagcgacg uaggaauaua uuauuuauca      780

aaauuugggc uauacucaac gaacaggaau gauauaguac aaucgcuaga aaaagccgua      840

gacauguaua aauaugguaa aauugcauuc gucgcaaugg aaagaauuac augggauuau      900

gacggaauag gguccaacgg caagaaagua gaucacgaua aauuuuuaga cgacgcugaa      960

aaacauuauu uaccaaaaac auauacuuuu gacaacggua cauucaucau uagggcagga     1020

gauaaaguuu ccgaagagaa aauaaaaaga uuauacuggg caagucgaga aguaaaauca     1080

caauuccaca gaguaguagg caacgauaaa gccuuagaag ucgguaaugc ugacgaugua     1140

uuaaccauga aaauauucaa caguccugaa gaauacaaau uuaauaccaa uauaaaugga     1200

guaaguaccg auaauggcgg acuauacaua gaaccucgag gaaccuucua cacguacgaa     1260

cgaacuccgc aacaaucaau auuuagucua gaagaacuau uucggcauga auauacgcac     1320

uacuuacaag cuagauaucu uguagacgga uuaugggggc aaggacccuu cuaugaaaag     1380

aaucgauuaa caugguuuga cgaaggaacu gcugaauuuu ucgcagguuc aacaagaacg     1440

ucaggaguac uaccaaggaa aaguauacua ggcuaccuug caaaagauaa aguugaucau     1500

cgauauucac uaaagaaaac acuaaauagu gguuaugacg acucagauug gauguucuau     1560

aacuaugguu uugcaguggc acauuaucua uaugaaaaag auaugccaac cuucauaaaa     1620

augaacaaag ccauauuaaa uacugacguc aaaucauacg acgaaauaau uaagaaauua     1680

ucagacgaug caaacaaaaa uacagaauau caaaaccaua uacaagaauu agcagauaaa     1740

uaucaaggug cagguauucc auuaguaucg gaugauuauu uaaaagauca uggauacaag     1800

aaagccagcg aaguauacuc ugaaauuagc aaagcagcgu cacucacgaa uacaucuguu     1860

acugcagaaa aaucacaaua uuuuaauaca uuuacacugc guggaaccua uaccggagaa     1920

acaucaaaag gugaauuuaa agacugggac gaaaugucaa agaaacuaga uggaacccuc     1980

gaaaguuuag ccaaaaauuc auggagugga uauaaaacuc uuacugcaua cuucacuaau     2040

uacagaguaa caucagacaa caaaguacaa uacgacguag uauuucaugg cgucuugaca     2100

gauaaugccg acauuucaaa uaacaaagcc ccaauagcua aagugacagg accaucaaca     2160

ggcgcagucg gaagaaauau ugaguucuca gggaaagaua guaaagacga agauggaaaa     2220

auaguuagcu augacuggga cuucggagau ggagcaacau cucgagguaa aaacuccgua     2280

cacgcauaua agaaagcugg aaccuauaac guuacauuaa aaguaacuga ugauaaagga     2340

gcaacugcaa cagaaaguuu uacuauagaa aucaaaaacg aagauaccac aacaccaaua     2400

acaaaagaaa uggaaccaaa cgacgacaua aaagaagcga auggacccau aguagaagga     2460

gucacuguua aaggagacuu aaaugggagc gacgaugccg acacuuuuua uuucgacguu     2520

aaagaagaug gagacguaac uauagaauua cccuacucug gaaguaguaa uuuuaccugg     2580

cuaguauaca aagaaggcga ugaucaaaac cauauagcgu caggaauaga uaaaaauaau     2640

ucaaaagugg gcacuuucaa aagcacaaaa ggaagacauu acguauucau uuauaaacac     2700

gauucagcau caaacauauc auacucgcuu aauauaaaag gacuaggaaa cgaaaaacuu     2760

aaagaaaaag aaaacaauga cucaucagac aaagccacag uaauuccaaa uuuuaacacu     2820

acuaugcaag gaagccuuuu aggagaugau aguagagauu auuauucauu cgaaguaaaa     2880

gaagaaggag aaguuaauau cgaacuagau aagaaagaug aguucggugu aacguggaca     2940

uuacacccug aauccaauau uaacgacaga aucaccuaug gacaaguuga cggaaauaaa     3000

gucagcaaca aaguuaaauu aagacccgga aaauauuacc uccuaguuua uaaauauagc     3060

ggaucaggaa acuacgaauu acgaguaaau aaaugaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  2407
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt12)

<400>  2407
gggagaaagc uuaccaugaa auggguaaca uucauaucau uacuuuuccu auuuucauca       60

gcauacagua ugaagaaaaa uauauuaaaa auauuaaugg acagcuauag caaagaauca      120

aaaauacaaa caguuagaag aguaacuagc guuagcuuau uagccguaua cuuaacaaug      180

aauacaagua gccuaguauu agcaaaaccg auagaaaaua caaacgacac gagcaucaaa      240

aacguugaaa aacuaagaaa ugcccccaac gaagaaaaca guaagaaagu cgaagacagu      300

aaaaaugaua aaguagaaca ugugaaaaac auagaagaag ccaaaguaga acaaguagcc      360

ccugaaguua aaagcaaauc aacgcuacgc agcgccagua ggagaagaag aaaaagaaua      420

gcaaauacua acucagaaaa auaugacuuc gaauacuuaa auggacuaag uuacacagaa      480

cuuaccaauc uuaucaaaaa cauaaaaugg aaucaaauaa auggacuauu caauuauucc      540

acugggucac aaaaauuuuu cggagauaaa aauagagugc aggcuauaau uaacgcacua      600

caagaaucag gaagaaccua cacagcaaac gauaugaaag ggauagaaac uuucacugaa      660

guacugcgag cgggauucua uuugggguac uauaacgacg guuuaucaua cuuaaacgac      720

agaaauuuuc aagacaaaug uauaccagca augauagcaa uacagaaaaa uccuaauuuu      780

aaacuaggga ccgcaguaca agacgaagug auaacaucac ucgguaaacu cauaggaaau      840

gcuucagcua augcggaagu aguaaauaau ugcguaccag uuuuaaaaca auucagagaa      900

aaccucaacc aauaugcacc cgacuaugua aaaggaacug caguuaacga acuuaucaaa      960

ggaaucgaau uugauuuuag cggagccgcg uacgaaaaag acgugaaaac aaugccuugg     1020

uauggaaaaa uagacccauu cauuaacgaa uuaaaagccu uaggccugua cgguaauaua     1080

acuucagcca cagaaugggc aagugacguu ggcauauacu auuugucgaa auuuggauug     1140

uauucaacaa accguaacga cauaguucaa agccuggaaa aagcaguaga uauguacaaa     1200

uauggaaaaa uagccuuugu agcaauggaa aggauuacau gggauuauga cggaauaggc     1260

ucaaauggua agaaaguaga ucaugauaag uuucuagacg augcagaaaa acacuaucuu     1320

ccaaagacau acaccuucga caauggaacu uuuauuauaa gggcaggcga caaaguaucc     1380

gaagagaaaa uaaaacguuu auacugggca ucacgggaag uaaaaagcca auuucauaga     1440

guaguaggaa acgacaaagc auuagaagua ggaaacgcag augacguacu cacaaugaaa     1500

auauucaauu cuccugaaga auauaaauuc aauacaaaua uaaauggagu caguacagac     1560

aauggaggac uauacauaga accuagaggg acauuuuaua cuuacgaaag aacaccccaa     1620

caauccauau uuucccuaga agaauuguuc cgacaugaau acacacauua uuuacaagcc     1680

cgauacuuag uagacggauu auggggacaa gguccauucu acgagaaaaa cagauugaca     1740

ugguucgacg aaggaacagc agaauuuuuc gccggaucaa cuagaaccuc cgguguauua     1800

ccaagaaaau ccauccuugg guacuuagca aaagauaaag uagaucaucg uuauucguua     1860

aagaaaacau uaaauagcgg cuacgaugau ucagauugga uguuuuauaa uuauggcuuu     1920

gcuguagcac auuaucuaua cgaaaaagau augccaacuu ucaucaaaau gaacaaagcg     1980

aucuuaaaua cagacguuaa aucauaugac gaaaucauaa agaaauuauc agaugaugca     2040

aauaaaaaca cagaauauca aaaccacaua caagaacuag cugauaaaua ucagggugca     2100

ggaaucccac ucguaucgga cgauuaccua aaagaccaug gauauaagaa agcaagcgaa     2160

guauacucag aaauuaguaa agcugcaucu cuuacaaaua caagcguaac ggcagagaaa     2220

agccaauauu ucaacacguu cacacuacgc ggaacauaua cuggagaaac aaguaaagga     2280

gaguucaaag auugggacga aaugucaaag aaauuagaug guacuuuaga aucauuagcc     2340

aaaaauagcu gguccgggua caaaacacuu accgcauacu uuacaaauua uagagucaca     2400

agcgauaaua aaguucaaua cgaugucguc uuucacggag uacuaacaga caacgcggau     2460

auaagcaaua auaaagcacc aauagcaaaa guaacaggac caucaaccgg agcuguugga     2520

agaaacauug aguucucagg aaaagacuca aaagacgaag auggcaaaau aguaagcuau     2580

gauugggauu uuggagacgg cgcaacaucc agaggcaaaa auagcgucca ugccuauaag     2640

aaagcaggaa cauacaacgu aacauuaaaa guaacagacg acaaaggagc caccgccacu     2700

gaaaguuuua cuaucgaaau caaaaaugaa gauacaacca ccccaauaac caaagaaaug     2760

gaaccuaaug augacauaaa agaagcuaau gggccaauug uagaaggagu cacagucaaa     2820

ggcgacuuaa acgggagcga cgacgcugau accuucuacu uugacguaaa agaagaugga     2880

gauguaacaa uagaacuacc auauucaggu ucauccaauu uuacauggcu aguguacaaa     2940

gaaggugacg accaaaacca uauagccagu ggaauugaca aaaacaauuc uaaagugggg     3000

acuuuuaaaa gcacaaaagg uagacauuau guauuuauau acaaacauga uagugcaagc     3060

aacauaucau acucucuaaa uaucaaaggc uuaggaaacg aaaagcuaaa ggaaaaggaa     3120

aauaacgauu ccucagauaa agcaacugug aucccaaauu ucaacacuac uaugcaaggc     3180

agccuucucg gugaugauag ccgagauuac uacuccuuug aagucaaaga agaaggugaa     3240

gucaacauag aauuggauaa gaaagaugag uucggcguca cauggacacu gcauccagaa     3300

ucaaacauaa acgauagaau caccuacgga caagucgacg gaaauaaagu aagcaauaaa     3360

gucaaauuaa gaccaggaaa auacuaccuu cuaguauaua aauacucugg aaguggaaau     3420

uacgaauuac gaguuaauaa auaaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  2408
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt12)

<400>  2408
gggagaaagc uuaccaugaa cuuuuugaag auaauacuaa auagaggaaa aacaaugaaa       60

agaaaaugcc uauccaaacg auuaaugcug gccauaacua uggcaacaau auuuacagua      120

aacaguacau uaccuauaua ugcagcugua gauaaaaaca acgcuacagc ugccguccag      180

aacgaaucua aaagguacac cguaucuuau cuaaaaacuc uaaacuacua ugacuuagua      240

gauuugcuag uaaaaacaga aauagagaau cuaccagacu uauuucaaua uucaagcgau      300

gccaaagagu ucuauggaaa uaaaaccaga augaguuuua uaauggauga aauagguaga      360

cgagcaccac aauacacaga aaucgaccau aagggaauac cgacacuugu agaaguggua      420

agagcaggau ucuauuuagg auuccauaau aaagaauuaa acgagauaaa caaacgaucc      480

uuuaaagaaa gagucauacc aagcauauua gcaauccaga aaaauccaaa uuucaagcua      540

ggaacagaag uacaagauaa aauuguaagc gcaacaggau uacucgcagg gaacgaaaca      600

gcacccccag aagucgugaa caacuucacc ccaauacucc aagacuguau caaaaauaua      660

gauagauacg cacuagauga ccuaaaaagu aaagcccuuu ucaacguacu ugcagcacca      720

accuaugaua uaacugaaua ccuacgagca acaaaagaga aaccagaaaa cacacccugg      780

uacgggaaaa uagacggcuu uauaaaugag uuaaagaaau uagccuuaua ugguaaaaua      840

aaugauaaua auucauggau aauagacaac ggcauuuauc auaucgcacc ucugggaaaa      900

uuacacagua auaacaaaau agguauugaa acacuaacag aaguaaugaa aguuuaucca      960

uaucuaagca ugcaacaccu ccaaucagca gaucaaauaa aacgacacua cgacucuaag     1020

gacgcagaag ggaacaaaau accacuagac aaauucaaga aagaaggaaa agaaaaauac     1080

ugcccaaaaa cauauacauu cgacgauggc aaaguaauua ucaaagcugg cgcaagggua     1140

gaggaagaaa aaguaaaacg ucuauauugg gcuucaaaag aaguaaauuc acaauucuuu     1200

cgaguuuacg gaauugauaa accauuagaa gaaggaaacc cagaugacau ucuaacuaug     1260

guuauauaua auucaccaga agaauauaaa cuaaacucag uauuauacgg auaugauacc     1320

aacaacggug ggauguacau agaacccgaa ggaacauucu uuacuuauga acgcgaagca     1380

caagaaagca cuuacacguu agaagaacua uuccgacacg aauauacaca uuacuuacaa     1440

ggacgcuaug caguuccagg acaaugggga cgaacaaaau uauaugauaa cgacagacua     1500

acaugguacg aagaaggagg agcagaauua uuugcuggua guacucgaac aaguggaaua     1560

cuacccagaa aaagcauugu aagcaacaua cauaauacaa cacgcaacaa cagauauaaa     1620

cuaucagaua cuguacauuc caaauauggc gccagcuuug aguucuacaa cuacgcaugc     1680

auguucaugg acuacaugua caauaaagac auggguauac ucaacaaacu aaacgaucuc     1740

gccaaaaaua acgacguuga cggauaugau aauuacauua gagaccucag uucaaauuau     1800

gcauuaaaug acaaauacca agaucacaug caagaaagaa uagauaacua ugaaaacuua     1860

acaguaccau ucguugcaga cgauuacuua guaagacacg cauauaaaaa cccuaacgaa     1920

auauauucgg aaauuucaga aguugcaaaa uuaaaagaug caaaaucuga aguaaagaaa     1980

agucaauauu uuucgaccuu cacauuacgu ggaagcuaua caggaggugc auccaaagga     2040

aaacucgaag aucaaaaagc aaugaacaaa uuuauagacg acucuuuaaa gaaacuagac     2100

acauauucgu ggagcgggua caaaacauua acggcauacu ucacgaauua uaaaguugac     2160

aguucaaaua gagucacaua ugauguaguc uuucacggau accuaccuaa cgaaggagac     2220

aguaaaaaua gucuccccua ugggaaaaua aauggcacau acaaagguac cgagaaagag     2280

aaaauaaaau uuuccucgga aggcucauuc gacccugaug gaaaaauagu aucauacgaa     2340

ugggacuucg gagauggaaa uaaaaguaac gaagaaaauc cagaacacuc auacgauaaa     2400

guagggaccu auaccguaaa acucaaagua acagaugaca aaggcgaaag cucaguuuca     2460

acaacaacug cagaaauuaa agauuuauca gaaaauaaau uaccaguaau auauaugcau     2520

guaccaaaaa guggggcacu aaaucaaaaa guaguguucu augggaaagg aacauaugau     2580

ccagacggau caauugcagg uuaccaaugg gauuuuggag augguucaga uuucucaagu     2640

gaacaaaauc caucccacgu uuauacaaag aaaggagaau acacaguaac uuuacgagua     2700

auggacaguu cagggcaaau gucggagaaa acaaugaaaa uuaaaauaac agauccagua     2760

uacccaauag gaacagaaaa agaaccuaau aauucaaaag aaacugcauc agggccaaua     2820

guacccggaa uacccguauc cgguacuaua gaaaacacau cagaucaaga cuacuucuau     2880

uuugauguua uaacgccagg agaaguaaaa auagauauca acaagcuagg auauggagga     2940

gcaacguggg uaguguauga ugaaaauaau aacgcaguuu cauaugcaac ugacgaugga     3000

caaaaccucu ccggaaaauu caaagcagau aaaccaggaa gguauuacau acaccuguac     3060

auguucaaug gcucuuauau gccguaucgu auaaauaucg aagggucagu aggaagauaa     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  2409
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt12)

<400>  2409
gggagaaagc uuaccaugaa acgaaaaugc uuaucaaaaa gauuaauguu agcaauaaca       60

auggccacua uauucacugu caauucaacc cuuccaauau acgccgcagu agacaagaac      120

aaugcuacag cagcaguaca aaaugaaagu aagagauaca caguaucgua ucuaaaaacu      180

cuaaacuauu augaccucgu ggaccugcua guaaaaacag aaauagaaaa uuuaccugau      240

uuauuccagu auucaucaga ugcaaaagag uucuauggca auaagacaag aauguccuuc      300

auaauggaug aaauaggcag acgagcacca caauacacug aaauugacca caagggaaua      360

ccaacccuag ucgaaguagu cagagcagga uucuaccuag gcuuccauaa uaaggaacua      420

aacgaaauaa acaaaagaag uuucaaagaa agagugauac caucaauauu agcaauacag      480

aaaaauccca acuuuaaacu uggaacagaa guacaagaca aaauugugag cgcaaccgga      540

uuacuagcag ggaacgaaac agcaccuccc gaaguaguga auaauuuuac gccaauauua      600

caagauugca uuaaaaacau agacagauau gcacuagaug auuuaaaauc uaaagcauua      660

uuuaacguac uagcagcucc cacauaugau auaacagaau accucagagc caccaaagaa      720

aaaccugaaa auacaccaug guauggaaaa aucgacggcu uuaucaauga acuuaaaaag      780

cuagcacuau auggaaaaau caacgauaac aacucaugga ucauagauaa uggaauauac      840

cauauagcac ccuuaggcaa acuucacuca aacaauaaaa ucggcauaga aacauuaacg      900

gaaguaauga aaguauaccc uuaucuaucu augcaacauu uacaaucagc agaucaaaua      960

aaacgccacu acgauaguaa agaugcagaa ggaaacaaaa uaccccucga caaguucaag     1020

aaagaaggaa aagaaaaaua uuguccaaaa acauauacgu ucgacgaugg aaaaguaaua     1080

auaaaagcag gagcaagagu agaagaggaa aaaguaaaaa gauuauacug ggcgucaaaa     1140

gaaguaaacu cacaauucuu cagaguuuau ggaauagaca aaccauuaga ggaaggaaau     1200

cccgaugaca uucuuaccau ggugaucuac aacaguccug aagaauauaa acuaaauucu     1260

guccucuacg gauaugauac aaacaacgga ggcauguaua ucgaaccaga aggaaccuuu     1320

uucacauaug agagagaagc ucaagaauca accuacaccc ucgaggaacu auucagacac     1380

gaauauacgc acuaucuaca aggcagguac gcaguacccg gacaaugggg ccguacaaaa     1440

cuauaugaca acgacagacu aacuugguac gaagaaggag gggcugaauu auuugccgga     1500

ucaacaagaa ccucagggau ucuuccacga aaaucgauag uuucgaauau acacaauaca     1560

accagaaaca auagauauaa auuaucagau acagugcauu ccaaauaugg ggcuucauuc     1620

gaguuuuaca auuaugcuug cauguucaug gauuauaugu auaacaaaga caugggaaua     1680

cucaacaaac uaaaugaccu cgcuaaaaac aaugacguag auggauacga caauuacaua     1740

cgcgauuuaa gcuccaacua ugcauuaaac gacaaauauc aagaucauau gcaagaaaga     1800

auagauaauu augagaaucu aacaguaccg uucgucgcag augauuacuu agugcggcac     1860

gcauauaaaa acccuaauga aauuuauagc gaaauaagug aaguugcaaa auuaaaagac     1920

gcaaaaagug aaguaaagaa aucacaauac uuuagcacau ucacauuaag aggaaguuau     1980

acuggaggag ccuccaaagg uaaacuagaa gaccaaaaag cuaugaacaa auuuauagau     2040

gauagucuua agaaacuuga caccuauuca uggaguggau auaaaacauu aacagcuuau     2100

uucacuaacu auaaaguaga uucaucaaau cgcguaacuu augaugucgu uuuccacggu     2160

uauuuaccca acgaaggaga caguaaaaac ucacuaccau acgguaaaau aaauggcacu     2220

uacaaaggaa cagaaaaaga gaaaauaaaa uucaguucug aaggaucauu cgacccagau     2280

ggaaaaauag ugagcuauga augggacuuc ggagauggua auaaaagcaa ugaagaaaau     2340

ccagaacaca guuaugacaa aguagguaca uacacuguua aauuaaaagu cacagacgau     2400

aaaggcgaaa guucaguauc aacaacaaca gccgaaauaa aagaucuaag cgaaaacaaa     2460

cuacccguca uauauaugca cguaccuaaa aguggagccc uuaaccaaaa agugguauuc     2520

uacggaaaag gaacauacga cccugacgga agcauagcag gauaucaaug ggacuucggu     2580

gacgguucgg acuucucuuc ugaacaaaau ccaagccacg uauacacaaa gaaaggagaa     2640

uacaccguaa cacuuagagu uauggacagc ucaggacaaa ugucagagaa aacaaugaaa     2700

aucaaaauua ccgacccugu auauccaaua ggaacugaaa aagaaccaaa uaacaguaaa     2760

gaaacagcua guggaccgau cguuccaggu auuccuguaa guggaacaau cgaaaacaca     2820

ucagaccagg acuauuuuua uuucgaugua auaacaccag gagaagucaa aaucgauaua     2880

aauaaacuag gauauggagg ggcuacaugg guaguauacg augaaaacaa caaugcagua     2940

uccuacgcga cagaugacgg acagaaccuu ucaggaaaau ucaaagcgga caaaccaggc     3000

agguacuaca uacaccuaua cauguucaac ggauccuaua ugccuuaucg aauuaauaua     3060

gaaggauccg uaggccguua aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  2410
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt12)

<400>  2410
gggagaaagc uuaccaugaa augggugaca uucauaucuc uacuuuuccu auucuccuca       60

gcauacucag uacaaaacga aucaaaaaga uacacaguga guuacuuaaa aacguuaaac      120

uacuaugacc uaguagaccu ucuaguaaaa accgaaauag aaaaucuacc agaccuauuc      180

caauacucuu cagaugccaa agaauuuuau ggaaauaaaa ccagaaugag uuucaucaug      240

gaugaaaucg gaaggagagc accacaauac acggaaauag aucacaaagg uauacccacu      300

uuaguagaag ucguaagagc aggauucuac uuaggauucc auaacaaaga acucaaugaa      360

auuaauaaaa gaucuuucaa agaaagggua auacccagca uacucgccau acagaaaaac      420

cccaacuuca aacuaggaac agaaguacaa gauaaaauag uaucagcaac ugguuuacuc      480

gcuggaaaug aaaccgcacc accagaagua guaaacaacu ucaccccuau ucuacaagac      540

ugcauuaaaa auauagacag auacgcccua gacgacuuaa aaucgaaggc ccucuuuaac      600

guacuagccg ccccaacaua ugauauaaca gaauacuuaa gagcaaccaa agaaaaacca      660

gaaaauacac ccugguacgg aaaaauagac ggauuuauaa augaauuaaa gaaauuagcg      720

uuauauggga aaauaaacga caauaauagu uggauaauag acaacggaau auaccacaua      780

gcaccauuag gcaaacuaca cuccaauaac aaaauaggga uagaaaccuu aacagaagua      840

augaaaguau auccauaucu aucaaugcaa cauuugcaau cagcagacca aauaaaacga      900

cauuaugaua guaaagacgc agaaggaaau aaaauaccac uagauaaauu caagaaagaa      960

ggaaaagaaa aauauugucc aaaaacauac acauucgaug acggaaaagu aauaauuaaa     1020

gccggugccc ggguagaaga agaaaaagua aaacgacugu auugggcuuc uaaagaaguc     1080

aauucacaau ucuuuagggu auacggaauu gauaaaccuc uagaagaagg uaacccagac     1140

gacauccuaa caauggucau auacaauagc ccggaagaau acaaauuaaa cucgguauua     1200

uacggguaug acacaaauaa cggcggcaug uacauugaac ccgaaggaac guucuucaca     1260

uaugaaagag aagcacaaga aucaacauac acacucgaag aacuauuuag acacgaauau     1320

acacauuauu uacaagggag auacgccgua cccggacaau ggggucgaac caaacuuuac     1380

gacaacgaca ggcuaacaug guacgaagaa gggggagcag aauuauucgc aggaucaaca     1440

agaaccucag gaauacuacc uagaaaaagu auaguaucaa auauacauaa uacaaccagg     1500

aauaacagau auaaauuaag ugacacaguc cauucaaaau auggagccuc cuuugaguuc     1560

uauaacuacg cauguauguu cauggauuac auguacaaca aagauauggg aauccuaaac     1620

aaacuaaacg accuagcuaa aaauaacgau guugacggau acgauaacua cauaagagac     1680

cucagcucaa acuaugcacu uaacgacaaa uaucaagauc auaugcaaga aagaauagac     1740

aacuacgaaa aucucacagu accauucgua gcagacgauu auuuaguaag acacgcauac     1800

aagaacccua acgaaaucua uuccgaaauu agcgaaguag cgaaacuuaa agacgcaaaa     1860

agugaaguaa agaaaaguca auacuucagc acauucacac uacgaggauc cuacacaggc     1920

ggcgcaagca aaggcaaacu agaagaucaa aaagcaauga acaaauucau agacgauuca     1980

cucaagaaau uagauacaua uagcuggagu ggauacaaaa cacuaacugc auauuucaca     2040

aacuacaaag uugacagcuc aaauagaguc acauaugaug uaguauucca cggauaucua     2100

cccaaugaag gugacagcaa aaacuccuua ccauacggaa aaauuaacgg gacauacaaa     2160

ggaacagaaa aagagaaaau aaaauucuca uccgaaggua gcuuugaccc cgauggaaaa     2220

auuguaucau augaauggga cuucggagac ggaaauaaau caaacgaaga aaauccugaa     2280

cacagcuaug auaaaguugg caccuauacc gugaaacuaa aagugacaga ugacaaaggu     2340

gaaucauccg uauccacaac gacagcagaa auuaaagacu uaagcgaaaa caaacuacca     2400

guaauauaca ugcauguacc aaaauccggc gcauuaaauc aaaaagucgu auuuuaugga     2460

aaagggacuu augaccccga ugggucaauc gcaggcuauc aaugggacuu cggcgauggc     2520

ucagacuucu caucagaaca gaacccaucu cauguuuaca caaagaaagg agaauacaca     2580

guaacauuac gagucaugga uucaucaggu caaaugucag agaaaacaau gaaaauaaaa     2640

auaacagauc cgguuuaccc aauaggaaca gaaaaagaac ccaacaauuc aaaagaaaca     2700

gcaaguggcc cuauaguucc agguauuccu guaucaggua caaucgaaaa cacaucagac     2760

caggauuacu uuuacuucga cgugauuacg ccaggagaag uuaaaaucga uauuaauaaa     2820

uuaggauaug guggagccac guggguagua uacgaugaaa auaauaaugc aguaucauau     2880

gccacagaug acggacaaaa ucuuucaggg aaauuuaaag cugauaaacc aggaagauau     2940

uauauacacc uuuacauguu caacgguuca uacaugccuu acagaauaaa uauagaagga     3000

uccguaggua gauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2411
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt12)

<400>  2411
gggagaaagc uuaccaugaa augggugaca uucaucucac uauuauuucu auucaguagc       60

gcauauucua ugaaacgaaa augcuuaucc aaaagacuaa ugcuagcaau aacaauggca      120

acaaucuuca ccguaaauuc aacauuacca aucuacgcag ccguagauaa aaacaaugca      180

acagcagcuc gaaggagaag gaaaagggua caaaacgaaa gcaaaagaua uaccgucagc      240

uaccuuaaaa ccuuaaauua cuacgacuua guagaucucu uaguaaaaac agaaauagaa      300

aacuuacccg auuuguuuca auauucaucc gacgcaaaag aguucuacgg aaauaaaaca      360

agaaugagcu ucauaaugga cgaaauaggu cggagagcuc cccaauauac cgaaauagau      420

cauaaaggaa uaccaaccuu aguagaagua guaagagccg gauuuuaccu uggcuuccau      480

aacaaagaac uaaacgaaau aaacaaacga uccuucaaag agcgcguaau accaaguaua      540

cuggccaucc agaaaaaccc aaacuuuaaa uuaggaacgg aaguucaaga caaaauagua      600

agugcaacag ggcuccuagc aggaaacgaa acagcucccc cugaaguugu aaauaacuuc      660

acaccaauac uucaagacug uauuaaaaac auagacagau acgcauuaga cgaccuuaaa      720

agcaaagcgu uauuuaacgu acuagcugca cccacuuaug acauaacuga auacuuaaga      780

gcaacaaaag aaaaaccaga aaacacaccu ugguauggca aaauagaugg auuuauaaau      840

gaacuaaaga aacuggcacu auauggcaaa aucaacgaua auaacaguug gauaauagac      900

aacgguauau aucauauagc accacuaggu aaauugcauu caaacaauaa aauugguaua      960

gaaacguuaa cagaggugau gaaaguauac ccauaccuau cuaugcaaca uuuacaauca     1020

gcggaucaaa uuaaaaggca cuaugauuca aaagaugcgg aagguaacaa aauaccacua     1080

gacaaauuca agaaagaagg aaaagaaaaa uauuguccca aaacauacac auuugaugau     1140

gguaaaguaa uaauaaaagc aggggcucga guagaagaag aaaaaguuaa acgacuauac     1200

ugggccucaa aagaagucaa cucucaauuu uuccgcguau acggaaucga uaaaccauua     1260

gaagaaggua auccggauga uauauuaacc auggugaucu acaacucacc agaagaauac     1320

aaacuaaauu caguccuaua uggauacgac acuaauaaug guggaaugua cauagaacca     1380

gaaggcacau ucuucacaua cgaaagagag gcucaagaau caacauacac acuagaagaa     1440

uuauuccgac acgaauacac acauuacuua caaggaagau acgcgguacc cggacaaugg     1500

ggaagaacaa aacuauacga uaaugaucga cuuacauggu augaagaagg aggagccgaa     1560

cuauucgcag gauccacgcg caccucaggg auucuuccaa gaaaaucaau aguaucaaau     1620

auacacaaua caacacgaaa uaacagauau aaauuaucag acacaguaca cuccaaauau     1680

ggcgcaaguu ucgaguucua caauuacgca uguauguuca uggauuacau guauaacaaa     1740

gauaugggga ucuuaaacaa acuaaacgau uuagcgaaaa acaaugacgu agacggcuau     1800

gacaacuaca uacgagacuu auccagcaau uacgcacuua acgauaaaua ccaagaucac     1860

augcaagaaa gaauagauaa cuacgaaaau cuaacagucc cauuugucgc agacgacuac     1920

cuggugagac acgcuuacaa aaauccaaau gaaauauacu cagaaauaag cgaaguagcu     1980

aaacucaaag acgccaaaag ugaaguuaag aaaagucaau acuuuucaac auucacccuc     2040

cggggaucau auaccggggg agcaucuaaa ggaaaauuag aagaccaaaa agccaugaau     2100

aaauuuauag augacucccu aaagaaacug gacacuuacu ccuggagugg guacaaaacu     2160

uuaacagcuu auuucaccaa cuauaaagua gacagcagca aucgagucac auaugacguc     2220

guguuucaug guuacuuacc aaacgaagga gacagcaaaa acucacuucc cuaugguaaa     2280

auaaacggua cauacaaagg aacagaaaaa gagaaaauua aauucucuuc ugaaggauca     2340

uuugauccag auggaaaaau cgugaguuau gaaugggacu uuggagacgg aaacaaaucu     2400

aacgaagaaa acccagaaca caguuaugau aaaguuggaa ccuacacagu aaaacuaaaa     2460

gugacugacg auaaaggaga aucaucaguc aguacaacua cagccgaaau aaaagaucua     2520

agcgaaaaua aacuccccgu aauauauaug cacgucccaa aaucaggagc cuuaaaucaa     2580

aaaguugucu uuuacgguaa aggaacauac gaucccgaug gaucaaucgc aggauaucaa     2640

ugggacuuug gagaugguag cgauuucucc agcgaacaaa accccucaca cguauauaca     2700

aagaaaggag aguauacagu aacauuaaga gugauggaua gcucgggaca aaugucagag     2760

aaaacaauga aaauaaaaau uacggaucca guauacccca uaggaacaga aaaagaacca     2820

aacaauucca aagaaaccgc uaguggucca aucguacccg gcauuccggu gagcgguacu     2880

auagagaaca caucagacca agauuacuuu uacuucgacg ucauuacacc aggcgaagua     2940

aaaauagaua uaaauaaauu agguuacgga ggugcaacuu ggguaguaua ugacgagaac     3000

aacaacgccg ucucauacgc aaccgacgac ggucaaaauc uaucaggaaa auucaaagca     3060

gacaaaccag guagauacua cauucaccua uacauguuca auggaaguua caugccauac     3120

agaauaaaca uagaaggauc cguuggaaga uaaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  2412
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt12)

<400>  2412
gggagaaagc uuaccauggg aacauggaua cuuuucgcau gccuacucgg agcagcauuc       60

gcaaugccac uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua      120

cuaacaccac uaaaauggua ccaaucaaua agaccaccau acccaucaua cggauacgaa      180

ccaaugggag gaugguuaca ccaccaaaua auaccaguac uaucacaaca acacccaccc      240

acacacacau uacaaccaca ccaccacaua ccaguaguac cagcacaaca accaguaaua      300

ccacaacaac caaugaugcc aguaccagga caacacucca ugacaccaau acaacaccac      360

caaccaaacc uaccaccacc agcacaacaa ccauaccaac cccaaccagu acaaccacaa      420

ccacaccaac caaugcaacc acaaccacca guacacccaa ugcaaccacu accaccacaa      480

ccaccacuac caccaauguu cccaaugcaa ccacuaccac caaugcuccc agaccuaaca      540

cuagaagccu ggccaucaac agacaaaaca aaaagagaag aaguagacua aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  2413
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt12)

<400>  2413
gggagaaagc uuaccaugcc ucuaccucca cauccagguc acccuggaua uauaaauuuc       60

ucuuacgaag uacuuacacc ucuaaaaugg uaucaaucua uacguccacc uuacccuuca      120

uauggauaug aaccuauggg uggaugguaa ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  2414
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt12)

<400>  2414
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc accaaugcua      120

ccagaccuaa cacuagaagc auggccauca acagacaaaa caaaaagaga agaaguagac      180

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  2415
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt12)

<400>  2415
gggagaaagc uuaccauggc aguaauggca ccaagaacac uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uacauaaacu ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca      180

ccauacccau cauacggaua cgaaccaaug ggaggauggu aaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  2416
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt12)

<400>  2416
gggagaaagc uuaccauggc aguaauggca ccaagaacac uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uacauaaacu ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca      180

ccaccaaugc uaccagaccu aacacuagaa gcauggccau caacagacaa aacaaaaaga      240

gaagaaguag acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  2417
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt12)

<400>  2417
gggagaaagc uuaccauggg aacauggauc cuauucgcuu gccuaguagg agcagcauuc       60

gccaugccau uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua      120

cuaacaccac ucaaauggua ccaaucaaug auaagaccac cauacucauc auacggauac      180

gaaccaaugg gaggauggcu acaccaccaa auaauaccag uaguaucaca acaacaccca      240

uuaacacaca cacuacaauc acaccaccac auaccaguag uaccagcaca acaaccaaga      300

guaagacaac aagcacucau gccaguaccc ggacaacaau caaugacacc aacacaacac      360

caccaaccca accuaccacu accagcacaa caaccauucc aaccacaacc aguccaacca      420

caaccacacc aaccaaugca accacaacca ccuguacaac caaugcaacc acuauuacca      480

caaccaccac ucccacccau guucccacua agaccacuac caccaauacu accagaccua      540

caccuagaag cauggccagc aacagacaaa acaaaacaag aagaagucga cuaaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  2418
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt12)

<400>  2418
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaucaa ugauaagacc accauacuca      120

ucauacggau acgaaccaau gggaggaugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  2419
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt12)

<400>  2419
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaucaa ugauaagacc accaccaaua      120

cuaccagacc uacaccuaga agcauggcca gcaacagaca aaacaaaaca agaagaagua      180

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  2420
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt12)

<400>  2420
gggagaaagc uuaccauggc aguaauggca ccaagaacau uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacauccagg acacccagga      120

uauauaaauu ucucauacga aguauuaaca ccacuaaaau gguaucaauc aaugauaaga      180

ccaccauaca gcucauacgg auacgaacca augggaggau gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  2421
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt12)

<400>  2421
gggagaaagc uuaccauggc aguaauggca ccaagaacac uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uacauaaacu ucucauacga aguacuaaca ccacuaaaau gguaucaauc aaugauaaga      180

ccaccaccaa uacuaccaga ccuacaccua gaagcauggc cagcaacaga caaaacaaaa      240

caagaagaag uagacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  2422
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt12)

<400>  2422
gggagaaagc uuaccauggg aaccuggaua uuauucgcau gccuacuagg agcagcauuc       60

ucaaugccac uaccaccaca cccaggacac ccaggauaca uaaacuucuc cuacgaagua      120

uuaacaccac uaaaauggua ccaaaacaug auaagacacc ccuacacauc auacggauac      180

gaaccaaugg gaggauggcu acaccaccaa auaauacccg uaguaucaca acaaacacca      240

caaucacacg cacuacaacc ccaccaccac auaccaaugg uaccagcaca acaaccagga      300

auaccacaac aaccaaugau gccacuacca ggacaacacu caaugacacc aacacaacac      360

caucaaccaa accuaccacu accagcacaa caaccauucc aaccacaacc aguacaacca      420

caaccacacc aaccacuaca accccaauca ccaaugcacc ccauacaacc acuacuacca      480

caaccaccac uaccaccaau guucucaaug caaucacuac uacccgaccu accacuagaa      540

gcauggccag caacagacaa aacaaaacgc gaagaaguag acuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  2423
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt12)

<400>  2423
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaaaua ugauaagaca cccauacaca      120

ucauacggau acgaaccaau gggaggaugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  2424
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt12)

<400>  2424
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaaaca ugauaagaca cccaucacua      120

cuaccagacc uaccacuaga agcauggcca gcaacagaca aaacaaaaag agaagaagua      180

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  2425
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt12)

<400>  2425
gggagaaagc uuaccauggc aguaauggca ccaagaacau uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacauccagg acacccagga      120

uauauaaauu ucucauacga aguauuaaca ccacuaaaau gguaucaaaa uaugauaaga      180

cauccauaua caucauacgg auacgaacca augggaggau gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  2426
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt12)

<400>  2426
gggagaaagc uuaccauggc aguaauggca ccaagaacac uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uacauaaacu ucucauacga aguacuaaca ccacuaaaau gguaccaaaa caugauaaga      180

cacccaucac uacuaccaga ccuaccacua gaagcauggc cagcaacaga caaaacaaaa      240

agagaagaag uagacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  2427
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt12)

<400>  2427
gggagaaagc uuaccauggg aacauggaua uuauucgcau gccuacuagg agcagccuuc       60

ucaaugccac uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacauaaga      120

cauccauaca caucauacgg auaugaacca augggaggau ggcuacacca ccaaauaaua      180

ccaguaguau cacaacaaac cccacaauca cacgcacuac aaccacacca ccacauacca      240

augguaccag cacaacaacc aggaauacca caacaaccaa ugaugccauu accaggacaa      300

cacuccauga caccaacaca acaccaccaa ccaaaccuac cacuaccagc acaacaacca      360

uuccaaccac aaccaguaca accacaacca caccaaccac uacaaccaca aucaccaaug      420

cacccaauac aaccacuacu accccaacca ccacuaccac caauguucuc aaugcaauca      480

cuacuaccag accuaccacu agaagcaugg ccagccacag acaaaacaaa acgagaagaa      540

guagacuaag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  2428
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt12)

<400>  2428
gggagaaagc uuaccauggg aacauggaua uucuucgcau gcuuacuagg agcauccuua       60

gcaaugccac uaccaccaca cccaggccac ccaggauaca uaaacuucuc auacgaagua      120

cuaacaccac uaaaauggua ccaaaacaug auaagacacc cauacacauc auacggcuac      180

gaaccaaugg gcggcuggcu acaccaccaa auuauaccag uaguaucaca acaaacacca      240

caaucacacg cacuacaacc ccaccaccac auaccaaugg uaccagcaca acaacccgga      300

auaccacaac aaccaaugau gccacuccca ggacaacacu caaugacacc aacacaacac      360

caccaaccaa accucccacu accagcacaa caaccauucc aaccccaacc aguacaacca      420

caaccacacc aaccacuaca accacaauca ccuaugcacc caauacaacc auuacuaccc      480

caaccaccac uaccaccaau guucucaaug caaucacuac uaccagaccu accacuagaa      540

gcauggccag caacagacaa aacaaaaaga gaagaagucg acuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  2429
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt12)

<400>  2429
gggagaaagc uuaccauggg aacauggaua cuauucgcau gccuacuagg agcagcauuc       60

ucaaugccac uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua      120

cuaacaccac uaaaauggua ucaaaacaug auaagacacc caucacuauu accagaccua      180

ccacuagaag cauggccagc aacagacaaa acaaaaagag aagaaguaga uuaaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  2430
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt12)

<400>  2430
gggagaaagc uuaccauggg aacauggaua cuauucgcau gccuacuagg cgcagcauuc       60

ucaaugccac uaccaccaca ccccggacac ccaggcuaca uaaacuucuc auacgaagau      120

uuauacuuag aagcaauaag aauagacaga acagcauuug uauuaacacc acuaaaaugg      180

uaccaaaaca ugauaagaca cccauacaca ucauauggau acgaacccau gggaggaugg      240

cuacaccacc aaauaauccc aguaguauca caacaaacac cacaaucaca cgcccuacaa      300

ccacaccacc acauaccaau gguaccagca caacaaccag gaauaccaca acaacccaug      360

augccacuac caggacaaca cucaaugaca ccaacacaac accaccaacc caaccuacca      420

cuaccagcac aacaaccauu ccaaccacaa ccaguacaac cacaaccaca ccaaccauua      480

caaccacaau caccaaugca cccaauacaa ccccuacuac cacaaccacc acuaccacca      540

auguucucaa ugcaaucacu acuaccagac cuaccacuag aagccuggcc agcaacagac      600

aaaacaaaaa gagaagaagu agacuaagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  2431
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt12)

<400>  2431
gggagaaagc uuaccauggg aacauggaua cuauucgcau gccuacuagg agcagcauuc       60

ucaaugccac ucccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua      120

cuaacaccac uaaaauggua ccaaaacaug auaagacacc caacaccaca aucacacgca      180

cuccaaccac accaccacau accaauggua ccagcacaac aacccggaau accacaacaa      240

ccaaugaugc cacuaccagg acaacacucc augacaccaa cacaacacca ccaaccaaac      300

cucccacuac cagcacaaca accauuccaa ccacaaccag uacaaccaca accacaccaa      360

ccacuacaac cacaaucacc caugcaccca auacaaccac uacucccaca accaccacua      420

ccaccaaugu ucucaaugca aucacuacua ccagaccucc cacucgaagc auggccagca      480

acagacaaaa caaaaagaga agaaguagac uaaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  2432
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt12)

<400>  2432
gggagaaagc uuaccaugcc acucccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacucacacc ccuaaaaugg uaccaaaaca ugauaagaca ccccuacaca      120

ucauacggau acgaacccau gggaggaugg cuacaccacc aaauaauacc aguagucuca      180

caacaaacac cacaaucaca cgcacuccaa ccacaccacc acaucccaau gguaccagca      240

caacaaccag gaauaccaca acaaccaaug augccacuac caggacaaca cucaaugaca      300

ccaacacaac accaccaacc aaaccuacca cuacccgccc aacaaccauu ccaaccccaa      360

ccaguacaac cacaaccaca ccaaccacuc caaccacaau caccaaugca cccaauacaa      420

ccacuacuac cacaaccacc acucccacca auguucucaa ugcaaucacu acucccagac      480

cuaccacuag aagcauggcc agcaacagac aaaacaaaaa gagaagaagu agacuaagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  2433
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt12)

<400>  2433
gggagaaagc uuaccaugcc ugggguugca agacuaccgu uacuauuggg auuacuacua       60

uuaccaaggc caggaagacc auuagauuua gcagauuaua cguaugauuu agcagaagaa      120

gacgauagug aaccauuaaa uuauaaagau ccauguaaag cagccgcguu uuuaggggac      180

auagcacuag augaagaaga ucuaagagca uuucaaguac aacaagcagu ugaccuaaga      240

agacacacag cuagaaaauc aucaauuaaa gccgcugucc cgggaaauac gaguacaccg      300

aguugucaau cuacuaacgg acagccacaa cguggugcau gcggaagaug gagaggacgc      360

ucaaggaguc ggagagcggc aacaagcaga ccagaaaggg ucuggccaga uggaguaaua      420

ccuuucguaa uaggaggaaa uuuuacagga agucaaagag caguauuccg ucaagcuaug      480

agacauuggg aaaaacauac cuguguaacg uuuuuagaaa gaacagauga agauaguuac      540

auaguguuua cguaucgacc augcggaugu uguucuuacg uaggaagacg aggggguggu      600

ccccaagcaa uaucaauagg uaaaaacugc gauaaauucg ggauaguagu acaugaacua      660

gggcauguag uuggauuuug gcaugaacac acacgacccg auagagauag acaugucuca      720

auaguaaggg aaaacauaca acccggacaa gaauauaauu ucuuaaaaau ggaaccacaa      780

gaaguugaaa guuuagguga aacguaugac uucgauagua uuaugcauua ugcacgaaau      840

accuuuagua gaggaauuuu ucuugacacu auaguaccga aauaugaagu aaauggugua      900

aaaccaccaa uaggucaaag aacaagauua ucaaaaggag auauagcaca agcucgaaaa      960

cuguacaaau gcccagcuug uggugaaaca uugcaagauu caacaggaaa uuucaguagc     1020

ccagaauacc caaacggaua uagugcgcau augcauugcg ucuggaggau uaguguaaca     1080

ccaggugaga aaauaauacu aaauuuuacg aguuuagacu uauaucgaag cagauuaugu     1140

ugguaugacu auguugaagu uagagaugga uuuuggagaa aagcaccauu aagaggaaga     1200

uuuuguggau caaaacuacc agaaccaaua guaaguacag auaguaggcu uuggguagag     1260

uucagaagcu cgaguaauug gguaggcaaa ggauucuuug cagucuauga agccauaugu     1320

ggaggggaug uuaagaaaga cuauggacac auacaaucac cuaauuaucc ggacgauuac     1380

cgaccaagca aaguuuguau uuggcggauu caaguaagcg aagguuucca cguaggacuu     1440

acauuccaau cuuuugaaau ugaacgccau gauaguugcg cauacgacua ucuagaagua     1500

agagaugguc auagcgaaag uucaacacua auuggaagau acugcggaua ugaaaaaccu     1560

gacgauauaa aaucaacaag cagucgauua uggcuaaaau uugugaguga cggaagcaua     1620

aauaaagcug gcuucgcugu aaacuuuuuc aaagaaguag augaauguag uagaccaaau     1680

aggggcggau gugaacaacg uuguuuaaau acuuuaggcu cguauaaaug cagcugugau     1740

cccggauaug aacucgcacc agauaaaaga agaugugaag cagcaugugg aggauuuuug     1800

acaaaacuua augguuccau aaccagucca ggguggccaa aagaauaucc gccaaauaaa     1860

aauugcauuu ggcagcuagu agcuccaacu caauaccgua ucaguuuaca auucgacuuc     1920

uuugaaacag aaggcaauga cguaugcaaa uacgauuuug uagaaguuag aucugggcua     1980

accgcugaca guaaauuaca uggaaaauuu uguggcucag aaaaaccaga aguaaucaca     2040

ucacaauaca auaacaugag agucgaguuu aaaagcgaua acacaguuag uaagaaaggu     2100

uuuaaagccc auuucuuuag ugauaaagau gaaugcucaa aagauaaugg agggugucaa     2160

caagauugcg uaaauacauu uggaagcuac gaaugccaau guagauccgg auuuguacuc     2220

caugauaaua aacacgauug uaaagaagca ggaugugacc acaaaguaac cucuacaucg     2280

gggacuauca cgaguccaaa cuggccagau aaauacccuu caaagaaaga augcacuugg     2340

gcgaucaguu cuacuccagg acauaggguu aaauuaacau uuauggaaau ggacauagaa     2400

ucacaaccug aaugugcuua ugaccauuua gaaguuuuug auggaagaga ugcuaaagcg     2460

ccuguuuuag gucgguuuug cggaaguaaa aagccugaac cugucuuagc cacuggcuca     2520

aggauguuuu uaagguuuua uucagacaac ucaguccaaa gaaaaggauu ucaagcaagu     2580

caugcgacag aaugcggagg ccaaguacga gcagauguaa aaacaaaaga ucuuuauucu     2640

caugcacaau uuggugauaa uaauuauccu ggaggaguug auugugagug gguaauagua     2700

gcagaagaag guuauggagu ugaauuagua uuucaaacgu uugaaguaga agaagaaacc     2760

gauugcgguu augacuacau ggaacuauuc gaugguuaug auucaacagc uccuagauua     2820

ggaagauauu gugggucagg cccgccagag gaaguauaua gugcaggaga uagcguucua     2880

guaaaauuuc acagcgacga cacaauaacc aagaaaggau uccaucuacg cuauacauca     2940

acuaaauucc aagauacacu acauagcaga aaauaaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  2434
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt12)

<400>  2434
gggagaaagc uuaccauggu cgcaggaaca agaugucuac uagcacuauu acuuccacaa       60

guucuacuag gaggagcagc uggauuagua ccagaauuag gaagaagaaa auuugcggca      120

gcaucaucug gaagacccag uucacaacca ucagacgaag uauuaucaga auuugaacuu      180

agacuacuua gcauguucgg auuaaaacaa cgucccacac caucuagaga ugcaguagua      240

ccacccuaua ugcuugaccu auacagacgu cacagcggcc aaccaggauc accagcacca      300

gaccauagac uagaaagagc cgcaucaaga gcaaacacag uaagaucauu ccaccaugaa      360

gaaagcuuag aagaauuacc agaaacauca gguaaaacua caagaagguu uuucuuuaac      420

uuaagcucua uaccaacaga agaauuuaua acaucagcag aauuacaagu auucagagaa      480

caaaugcaag acgcacuagg caauaauagc agcuuucacc acagaauaaa uauauaugaa      540

auuauaaaac cagcaacagc aaacucaaaa uuuccaguaa caagacuauu agacacacga      600

cuaguaaauc aaaaugcauc aagaugggaa uccuucgacg uaacaccagc aguaaugaga      660

uggacagcac aaggacacgc aaaccaugga uuuguaguag aaguagcuca cuuagaagaa      720

aaacaaggag uaaguaaacg ucauguaaga auuagcagaa guuuacauca agacgaacau      780

uccuggucuc aaauuagacc acuacuagua acauucggac augacggaaa aggacaccca      840

cuacacaaaa gagaaaaacg acaagcaaaa cauaaacaac guaaaagauu aaaauccuca      900

uguaaaagac auccauuaua cguagauuuc ucagacguag gauggaacga cuggauagua      960

gcaccacccg gauaccacgc uuucuauugc cauggagaau gcccauuccc acuugcagac     1020

caucuaaaca gcacaaauca cgccauugua caaacauuag uaaacagcgu aaacuccaaa     1080

auaccaaaag caugcugcgu uccaacagaa uuaagcgcaa uaucaauguu auacuuagac     1140

gaaaaugaaa aaguaguacu aaaaaauuac caagacaugg uaguagaagg cuguggaugc     1200

cgcuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  2435
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt12)

<400>  2435
gggagaaagc uuaccaugau accaggaaau agaaugcuua ugguaguauu acuaugccaa       60

guauuacuag gaggugcauc ccaugccuca uuaauaccag aaaccggcaa aaaaaaagua      120

gcugaaauac aaggacaugc aggaggaaga agauccggac aaucacacga gcuacuaaga      180

gacuuugaag cuacauuauu acaaauguuu ggauuacgaa gaagaccaca accuucaaaa      240

ucagcuguca uuccagauua uaugagagac uuauauagau uacaaucugg ugaagaagaa      300

gaagaacaaa uccacucaac uggacuggaa uauccagaaa gaccagcuuc aagagcuaau      360

acuguucguu cauuucauca cgaagaacau uuagaaaaca uaccaggaac aagcgaaaau      420

agugcauuua gauucuuauu caaccuaucc agcauuccag aaaacgaagu aauaucaagu      480

gcagaauuaa gauuauuucg ugaacaagua gaucaaggac cagacuggga aagaggauuu      540

cacagaauua acauauauga aguuaugaaa ccaccugcag aagucguacc aggucaccua      600

auaacaagau uauuagauac aagacuagua caucauaacg ucacaagaug ggaaacuuuu      660

gacguaucac cagcaguauu acgauggaca cgagaaaaac aaccaaauua cggucuagca      720

auagaaguaa cacaccuaca ucaaacaaga acccaccaag gacaacaugu acgaauauca      780

agaucauuac cacaaggaag cggaaacugg gcacaauuaa gaccacuacu aguuacuuuu      840

ggacacgaug gaagaggaca cgcacuaaca cggagaagaa gagcaaaacg uucaccaaaa      900

caccauucuc aaagagcaag aaaaaaaaau aaaaacugca gacgacauag cuuauaugua      960

gauuucucag auguagggug gaaugacugg auaguagcac cuccaggaua ccaagcauuu     1020

uacugucacg gugacugucc auuucccuua gccgaucacu uaaacucaac aaaucaugca     1080

auaguacaaa cacuaguaaa caguguaaac ucaaguauac cuaaagcaug cugcguacca     1140

acagaacuau cagcaauuuc aauguuauac cuagacgaau augacaaagu uguauuaaaa     1200

aauuaucaag aaaugguugu agaaggaugu ggauguagau aaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  2436
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt12)

<400>  2436
gggagaaagc uuaccaugcc aggacuaggu agaagggccc aauggcuaug uugguggugg       60

ggucuauuau guucauguug uggacccccu ccucuaagac caccauuacc agcugcugca      120

gcagcagcag ccggcgggca auuacuagga gauggaggcu cgccaggaag aacagaacaa      180

ccaccaccau caccacaauc aucaucaggu uuccuauaca gacgacuuaa aacacaagaa      240

aaacgagaaa ugcaaaaaga aauauuaucu guuuuagguc uaccacauag accuagacca      300

cuacauggcc uacaacaacc ucaaccucca gcccuucgcc aacaagaaga acaacaacaa      360

caacaacaau uaccaagagg ugagccacca cccgguagau uaaaaucagc uccuuuauuc      420

auguuagauu uauacaacgc ccuauccgcc gauaaugaug aagauggagc aucagaaggc      480

gagaggcaac aaucauggcc gcaugaagca gcuucaucau cacaacgccg acaaccaccu      540

ccuggugcug cacauccauu aaaucguaaa agccuacuug caccaggauc aggaucugga      600

ggagccucac cacuaacaag cgcacaagau ucagcauuuc uaaaugacgc ugauaugguc      660

augaguuuug uaaaucuagu agaauacgau aaagaguucu cuccaagaca aagacaucau      720

aaagaauuua aauuuaaucu aucucaaauc ccagaaggag aaguaguaac agcggcagaa      780

uuuagaauau auaaagauug uguaauggga ucauucaaaa aucaaacuuu ucuaauuuca      840

auauaccaag uauuacaaga acaucaacau cgcgacucag accucuuuuu acucgacacc      900

cgaguuguuu gggcauccga agaaggcugg cuagaauuug auauuacagc aacaucaaau      960

uuauggguag uaaccccuca acauaacaug gguuuacaau uaaguguagu aacaagagac     1020

ggaguucacg uccacccaag agcugcagga uuaguaggaa gagauggacc auaugacaaa     1080

caaccauuca ugguugcauu cuuuaaaguu agugaaguuc auguacgaac aacaagauca     1140

gcaaguucaa gaagaagaca acaaucuaga aaccgaagua cacaaucaca agauguugca     1200

cgaguaucau cugccaguga cuauaauuca ucagaauuaa aaacagcaug uagaaaacac     1260

gaauuauacg uaucauuuca agauuuaggu uggcaagacu ggauaauagc accaaaagga     1320

uacgcagcaa auuauuguga cggcgaaugu ucauuuccuu uaaaugcaca uaugaaugca     1380

acaaaccaug caauagucca aacauuaguc cacuuaauga auccagaaua cguaccaaaa     1440

ccuuguugug ccccaacaaa auuaaaugca aucucaguac uauacuucga ugauaauuca     1500

aauguaauau uaaagaaaua ccgaaauaug guaguaagag cuugcggcug ucacuaagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  2437
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt12)

<400>  2437
gggagaaagc uuaccaugca ugucagauca cuuagagcag cagccccaca uucuuucgua       60

gcauuauggg caccauuauu cuuauuaaga agcgcacuag cagacuuuuc auuagacaau      120

gaaguacaua guagcuuuau acauagacgc cuaagaucac aagaaagacg agaaaugcaa      180

agagaaaucc uaucaauauu aggauuacca cauagaccaa gaccucaucu acaaggaaaa      240

cacaacuccg cuccaauguu cauguuagac cuauauaacg caauggcugu cgaagaagga      300

ggagguccag gaggacaagg uuuuaguuau cccuacaaag caguauuuag cacacaaggc      360

ccaccacucg caagcuuaca agauucccau uuccuaacag augccgauau gguuaugagu      420

uucguuaauc uuguagaaca cgauaaagaa uucuuccacc cuagauauca ccaucgagag      480

uucagauucg aucuuucaaa aauaccagaa ggagaagccg uuaccgcagc agaauuuaga      540

auauauaaag auuacauccg cgaacgauuu gacaaugaaa cauucagaau aucaguauau      600

caaguacuac aagaacaucu agggagagaa ucagaucuau uuuuauuaga cucuagaaca      660

cuaugggcau cagaagaagg augguuaguu uucgauauaa cagccacaag caaucacugg      720

guaguaaacc cuagacacaa cuuaggauua caauuaagcg uagaaacacu cgacggccaa      780

aguauaaacc ccaaacuagc aggacuaaua ggacgacacg gcccacaaaa caaacaacca      840

uuuauggucg ccuuuuucaa agcuacagaa guacauuucc gaucaauacg aucuacagga      900

uccaaacaaa gaucacaaaa cagaucuaaa acaccaaaaa aucaagaagc auuaagaaug      960

gccaauguag cagaaaauag cucaucagau caacgacaag caugcaaaaa acaugaacua     1020

uacgugaguu ucagagaucu cggauggcaa gauuggauaa uagcaccaga aggauaugca     1080

gccuauuauu gugaagguga augugcauuu ccacuaaauu cuuacaugaa ugcaaccaau     1140

cacgcaauag uucaaacacu aguacacuuu auaaacccag aaacaguacc aaaaccuugu     1200

ugcgcaccaa cacaauuaaa cgcaaucuca guauuauacu ucgaugauag uucuaacgua     1260

auauuaaaaa aauacagaaa caugguaguc agagcaugcg guugucacua aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  2438
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt12)

<400>  2438
gggagaaagc uuaccaugaa agcaucagca gcacuacuau gccuacuacu aacagcagca       60

gcauucucac cacaaggacu agcacaacca guaggaauaa acacaucaac aacaugcugc      120

uacagauuca uaaacaaaaa aauaccaaaa caaagacuag aaucauacag aagaacaaca      180

ucaucacacu gcccaagaga agcaguaaua uucaaaacaa aacuagacaa agaaauaugc      240

gcagacccaa cacaaaaaug gguacaagac uucaugaaac accuagacaa aaaaacacaa      300

acaccaaaac uauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  2439
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt12)

<400>  2439
gggagaaagc uuaccaugcu acucacguug auaauauuau uaccaguagu aucaaaauuc       60

ucuuuuguua gccuaagugc cccacaacau uggucuuguc cagaagggac guuagccggg      120

aauggaaaca guacaugugu gggaccugcc ccauuuuuaa uauuuucaca cggaaauucc      180

aucuuuagaa ucgauacuga agggacaaau uaugaacaau uaguuguaga ugccggugua      240

ucaguaauca uggacuucca uuauaaugaa aaacggauuu acuggguuga ucucgaaaga      300

caacuacuuc aaagaguguu uuuaaauggg aguaggcaag aaagagucug uaauauugag      360

aaaaauguau caggaauggc uauaaauugg auaaacgaag agguaauaug gucuaaucaa      420

caagaaggua uuauaacugu gacugauaug aaaggaaaua acucacauau ccuccuaucu      480

gcucuaaaau auccugcuaa cguggcaguu gauccagucg aacgauuuau cuuuugguca      540

ucagaggucg caggaucgcu auauagagca gacuuagaug guguaggagu aaaagcauua      600

cuagaaacca gcgagaaaau aacugcagua aguuuagaug uacucgacaa aagauuauuc      660

uggauacaau acaauagaga aggaucaaau ucacuaauau guucuuguga cuaugauggc      720

ggaagcgucc acauaucuaa acaccccaca caacauaauu uauuugcgau gaguuuauuu      780

ggugauagaa uauuuuauag uacguggaaa augaaaacca uauggauagc uaauaaacau      840

acaggaaaag acaugguccg aauaaaccua cacucauccu uuguaccucu aggggaauug      900

aaaguaguac auccacuagc acaaccaaaa gcggaagacg acacauggga accggaacaa      960

aaacucugua aacucagaaa ggguaauugu ucgaguacug uauguggaca agaucuacaa     1020

agccauuuau guaugugcgc agaaggauau gcuuuaucaa gagaucgaaa auauugcgaa     1080

gaugucaaug agugugcauu uuggaaucau ggauguaccc uuggcugcaa aaauacccca     1140

ggcucauauu auugcacuug uccaguagga uuuguauugu uaccugaugg aaagcgaugu     1200

caucaacuug uaaguugucc acgaaauguu agugaauguu cacaugauug cguguuaaca     1260

ucagaaggcc cauuaugcuu cugcccagaa ggaucagugu uagaaagaga uggcaaaacu     1320

ugcaguggau gcaguagccc agacaauggu ggauguaguc aauuaugugu uccguuaucc     1380

ccagugucgu gggaauguga cuguuuucca ggauaugauu uacagcuaga cgaaaaaucu     1440

ugcgcagcaa gcgguccaca acccuuuuua cuauuugcaa auucccaaga cauucgucac     1500

augcauuuug augguacuga uuaugguaca uuauuaucac aacaaauggg uaugguauau     1560

gcauuagacc augauccugu cgaaaacaaa auauauuucg cucauacagc cuuaaagugg     1620

aucgaacgcg cuaacaugga uggaagucaa agagaaaggc ucauugaaga aggagucgau     1680

guacccgaag gcuuagcagu agacuggaua ggccgccgau uuuauuggac agauagaggu     1740

aaaagucuua uaggacguuc agacuuaaau ggaaaaagaa guaaaauuau aacaaaagaa     1800

aacauaucac aaccuagggg aauagcagua cauccaaugg caaaacgccu cuuuuggaca     1860

gauacaggca uaaauccuag aauugaaagu ucuagcuuac agggacuagg ccggcuagua     1920

auugccucau cagaccuaau auggccaagu gggauaacca uagauuuucu cacggacaaa     1980

uuguauuggu gcgaugcaaa acagucagua auagaaaugg cuaaucucga ugguucaaag     2040

agaaggagau uaacacagaa cgauguuggu cacccauucg caguagcagu auucgaggau     2100

uacgucuggu uuucggauug ggcaaugcca aguguaauga gaguaaacaa aagaacaggu     2160

aaagauagag uacgauuaca aggauccaug uuaaagcccu ccucauuagu agucguucau     2220

ccauuggcua aaccaggagc cgacccaugc uuauaccaaa auggugguug ugaacacauu     2280

uguaagaaaa gauuaggaac agccuggugu ucaugcagag aaggcuucau gaaagcauca     2340

gauggaaaaa caugccuagc auuagaugga caccaacuac uagcaggagg agaaguugac     2400

cucaaaaacc aaguaacgcc cuuagauaua uuaaguaaaa cucgaguuag ugaggacaac     2460

auaacagaaa gucaacacau guuaguggcu gaaauaaugg uaagugauca agacgauugu     2520

gcaccaguag gauguucaau guaugcacgc uguaucucag aaggcgaaga ugcaacuugc     2580

caaugccuaa aaggcuucgc gggcgaugga aaacuauguu cagacauaga ugaaugugaa     2640

auggguguuc cuguaugucc cccagcgucc ucaaaaugca uaaauaccga aggcggcuau     2700

guaugucguu guucagaagg guaccaaggu gauggaaucc auuguuuaga uauagacgaa     2760

ugucaauuag gcgaacauag uuguggugag aacgcuucuu gcaccaacac agaaggaggu     2820

uacacaugua ugugcgcagg gaggcuaagu gagccaggau uaauuugucc agauaguaca     2880

ccaccucccc accuaagaga ggaugaucau cauuacucag uaagaaauuc agauagugaa     2940

uguccauuau cucacgaugg uuacugccua caugacggug uaugcaugua uauagaagcc     3000

uuagauaaau augcuuguaa cuguguaguc ggcuacauag gagaaaggug ucaauauagg     3060

gaccuaaaau ggugggaauu acgacaugcu ggccaugggc aacaacaaaa aguaauaguu     3120

guagcagucu gugucguagu ucuaguaaug cuccucuuac uaucccuaug gggugcucau     3180

uauuaccgaa cgcaaaaacu ucugaguaaa aauccuaaaa auccauacga agaaucauca     3240

agagauguac gaucaaggag accagccgau acagaagaug ggaugucguc uugcccacag     3300

ccaugguucg uuguaauaaa agaacaccaa gauuugaaaa acggagguca accugucgca     3360

ggagaggaug gacaagcugc agaugguagu augcaaccca caaguuggag acaagaaccc     3420

caauuaugcg gaaugggaac ggaacaaggg ugcuggauuc caguaucgag cgacaaaggg     3480

ucuugccccc aaguaaugga aagaucguuc cauaugcccu cauacggaac gcaaacuuua     3540

gaaggaggag uagagaaacc acauuccuua cuaagcgcaa auccauuaug gcaacaacga     3600

gcuuuagauc caccacauca aauggaauug acacaauaag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  2440
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt12)

<400>  2440
gggagaaagc uuaccaugac agcaggaaga agaauggaaa ugcuaugugc aggaagagua       60

ccagcacuau uacuaugucu aggauuccau cuauuacaag caguauuaag uacaacagua      120

auaccaagcu guauaccagg agaaagcuca gacaauugca cagcauuagu acaaacagaa      180

gacaauccaa gaguagcaca aguaagcaua acaaaaugcu caagugauau gaauggauau      240

ugcuuacacg gacaauguau auaucuagua gacaugagcc aaaacuauug cagaugcgaa      300

guaggauaca cgggaguaag augugaacac uucuuucuaa caguacauca accacuauca      360

aaagaauacg uagcauuaac aguaauauua auaauacuau uucuaauaac aguaguagga      420

agcacauacu auuucuguag augguacaga aacagaaaau caaaagaacc aaaaaaagaa      480

uaugaaagag uaacaucagg agauccagaa cuaccacaag uauaaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  2441
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt12)

<400>  2441
gggagaaagc uuaccauggc agaaggagaa auaacaacau ucacagcacu aacagaaaaa       60

uucaaccuac caccaggaaa cuacaaaaaa ccaaaacuac uauacugcuc aaacggagga      120

cacuucuuaa gaauacuacc agacggaacc guagacggaa caagagacag aucagaccaa      180

cacauacaac uacaauuauc agcagaauca guaggagaag uauacauaaa auccacagaa      240

acaggacaau acuuagcaau ggacacagac ggacuacuau acggaucaca aacaccaaac      300

gaagaaugcc uauuccuaga aagacuagaa gaaaaccacu acaacacaua cauaucaaaa      360

aaacacgcag aaaaaaacug guucguagga cuaaaaaaaa acggaucaug caaaagagga      420

ccaagaacac acuacggaca aaaagcaaua cuauuccuac cccuaccagu auccucagac      480

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  2442
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt12)

<400>  2442
gggagaaagc uuaccauggu agggguggga ggaggagacg uagaagacgu aacaccaaga       60

ccaggaggau gucaaauaag uggaagagga gcaagagguu guaauggaau accaggagcg      120

gcagcauggg aagcagcauu accgagaaga agaccgagaa gacacccaag uguaaauccu      180

agaucaagag cagcuggaag cccaagaaca cgaggaagaa gaacagaaga aaggccuagu      240

ggaaguagau uaggggacag aggaagagga agagcauugc caggaggaag acuaggcgga      300

agaggaagag gaagagcacc agaaagagua ggagguagag gaagaggaag aggaacagca      360

gcaccaagag cagcaccagc agcaagggga aguagaccag gaccagcggg aacaauggca      420

gcaggaagua uaacaacacu uccagcauug ccagaagaug gaggaagugg cgcauuuccg      480

ccaggacauu uuaaagaucc aaagagauua uacuguaaaa auggagguuu uuuuuuaaga      540

auacauccag auggaagagu agauggagua agagaaaaaa gugauccaca uauaaaauua      600

caauuacaag cagaagaaag aggaguagua aguauaaaag gaguaugugc aaacagauau      660

uuagcaauga aagaagaugg aagauuacua gcaaguaaau guguaacaga ugaauguuuu      720

uucuuugaaa gauuagaaag uaauaauuau aauacguacc gaaguagaaa auauacaagu      780

ugguauguag cguuaaaaag aacaggacaa uauaaauuag gaagcaaaac aggaccggga      840

caaaaagcaa uauuauuuuu accuaugagu gcgaaaaguu aaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  2443
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt12)

<400>  2443
gggagaaagc uuaccaugca caaauggaua cuaacaugga uacuaccaac acuacuauac       60

agaagcugcu uccacauaau augcuuagua ggaacaauaa gccuagcaug uaacgauaug      120

acaccagaac aaauggcaac aaauguaaac ugcagcucac ccgaaagaca cacaagauca      180

uacgacuaca uggaaggcgg agacauaaga guaagaagac uauucugcag aacacaaugg      240

uacuuacgaa uagacaaaag aggaaaagua aaaggaacac aagaaaugaa aaacaacuac      300

aacauaaugg aaauaagaac aguagcagua ggaauaguag caauaaaagg aguagaauca      360

gaauucuacc uagcaaugaa caaagaagga aaacuauacg caaaaaaaga augcaacgaa      420

gacugcaacu ucaaagaauu aauacuagaa aaccacuaua acacauacgc aagcgcaaaa      480

uggacacaca acggaggaga aauguucguc gcacuaaacc aaaaaggaau accaguaaga      540

ggaaaaaaaa caaaaaaaga acaaaaaaca gcacacuucc uaccaauggc aauaacauaa      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  2444
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt12)

<400>  2444
gggagaaagc uuaccaugaa acuacuacca agcguaguac uaaaacuauu cuuagcagca       60

guacuaagcg cacuaguaac aggagaaagc cucgaaagac uacgaagagg ccuagccgca      120

gguacaucaa acccagaccc accaacagua ucaacagacc aauuacuacc acuaggagga      180

ggaagagaca gaaaaguaag agaccuucaa gaagcagacc uagaucuacu aagaguuaca      240

uuaucaucaa aaccacaagc acuagcaaca ccaaacaaag aagaacacgg aaaaagaaaa      300

aaaaaaggaa aaggacuagg caaaaaaaga gacccaugcu uaagaaaaua caaagacuuc      360

ugcauacacg gagaaugcaa auacguaaaa gaacuaagag caccaucaug cauaugccac      420

ccaggauauc acggagaaag augccacgga uuaagccuac caguagaaaa uagacuauac      480

acauacgacc acacaacaau acuagcagua guagcaguag uacuaucauc aguaugucua      540

cuaguaauag uaggacuauu aauguucaga uaccacagaa gaggcggaua cgacguagaa      600

aacgaagaaa aaguaaaacu aggaaugaca aauucacacu aaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  2445
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt12)

<400>  2445
gggagaaagc uuaccaugug gguuacaaaa cuauuacccg ccuuacuauu acagcauguc       60

uuacuacauc uauuacuauu acccauagcu auaccauaug cugaaggcca acguaaaaga      120

agaaauacaa uucaugaauu uaaaaaauca gcuaaaacaa cauuaauaaa aauagaccca      180

gcuuugaaaa uaaaaacaaa aaaaguaaac accgcagauc aaugugcaaa ucgauguaca      240

cgaaacaaag gauuacccuu uacauguaaa gcauuuguau uugauaaagc cagaaaacaa      300

ugcuuguggu uuccuuucaa cucaauguca ucaggaguaa aaaaagaauu uggccacgaa      360

uucgaucuau augaaaauaa agauuauaua agaaauugua uaauaggaaa aggacgauca      420

uauaaaggaa caguaaguau aacaaaaagc ggaauaaaau gucaaccgug guccaguaug      480

auaccacaug aacauucauu uuuaccauca ucauaccgag guaaagacuu acaagaaaau      540

uacugcagaa auccacgagg agaagaagga ggaccauggu gcuucacauc aaauccagaa      600

guucgauaug aaguauguga cauuccucaa uguucagaag uagaaugcau gacuuguaau      660

ggagaaucuu auagagguuu aauggaccau acagaaagug gaaaaauaug ccaacgaugg      720

gaucaccaaa caccacauag acacaaauuc cuaccagaaa gauacccaga caaaggauuu      780

gaugauaacu acuguaggaa cccggaugga caaccaaggc cauggugcua uacauuagau      840

ccacauacca gaugggaaua uugugcaaua aaaacuugug cagauaauac aaugaaugac      900

accgauguac cacuugaaac cacagaaugu auacaagguc aaggagaagg auaucgagga      960

acaguaaaua caauauggaa uggaauaccg ugucaacgau gggauaguca auacccccau     1020

gaacaugaca ugacaccaga aaauuuuaaa ugcaaagauc uaagggaaaa uuauuguagg     1080

aauccagaug gaucagaauc accuuggugu uucaccacag auccaaauau acgcguugga     1140

uauuguucac aaauaccaaa uugcgacaug agucacggac aggauugcua uagagguaau     1200

ggaaaaaauu auaugggaaa ccuaucacaa acaagaucag gucuaacaug cucaaugugg     1260

gacaaaaaca uggaagauuu acauaggcac aucuucuggg aaccagaugc aagcaaauua     1320

aaugaaaauu auugucgaaa uccagaugac gacgcacaug gaccauggug uuacacagga     1380

aacccacuaa uaccauggga cuauugcccc auaucaagau gcgaaggaga uacuacaccc     1440

acuauaguaa aucuagauca cccuguaaua ucaugugcaa agaccaaaca acucagggua     1500

guaaacggca uaccaacucg aaccaauauu ggauggaugg uuucacuaag auaccgcaac     1560

aagcauauau gcggaggaag ccuaauuaaa gaaucauggg uauugacagc aagacaaugu     1620

uucccaagcc gagaccuuaa agauuaugaa gcaugguuag gaauacacga cguacauggc     1680

agaggagaug aaaaaugcaa acaaguacuu aacguuucuc aauuagucua cggaccagaa     1740

ggauccgacu uaguacuaau gaaauuagca agaccagcag uucuagauga uuuuguaucu     1800

acaauagauc uaccaaacua cggauguaca auaccugaaa aaacaagcug caguguauac     1860

ggaugggguu auacuggccu uauaaauuau gacggacucc uaaggguagc ucauuuauau     1920

auaaugggaa augaaaaaug cucccaacau caucguggaa aaguuacacu aaaugaauca     1980

gaaauaugcg caggugcaga aaaaauaggu ucaggaccau gugagggaga uuauggugga     2040

ccauuaguuu gugaacaaca uaaaaugcga augguccuag gaguaauugu accaggaaga     2100

ggaugcgcaa uaccuaauag acccggaauu uucgucagag uagcauacua ugcuaaaugg     2160

auacauaaaa uaauacuaac guauaaagug ccucaaucau aaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  2446
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt12)

<400>  2446
gggagaaagc uuaccauggc aaaagcagca gccauaggaa uagaucuugg uacaacauau       60

ucaugcguag gcguauuuca acauggaaaa guagaaauaa uagcaaacga ccaaggcaac      120

cgaacaacac cauccuacgu ggcuuucaca gacacagaaa gacuaauugg cgaugcagcu      180

aaaaaucaag uugcauuaaa uccacaaaac acaguauuug acgcaaaaag acucauagga      240

agaaaauuug gggauccugu aguccaaagc gauaugaaac acuggcccuu ucaaguaaua      300

aacgacggcg acaaaccaaa gguacaggua aguuauaagg gagaaacaaa agcauuuuac      360

cccgaagaaa ucagcagcau gguauuaacu aaaaugaaag aaauagccga ggcauauuua      420

ggauauccag uuacaaacgc agucauaacu guaccagcau acuuuaauga uucacaaagg      480

caagcaacaa aagaugcagg aguaauagcu ggauuaaacg uauuaagaau aauaaacgaa      540

ccaacagcag cagcaauagc guaugguuua gaccgaacag gcaaaggaga gagaaacgua      600

cuaaucuuug aucuaggagg aggaacauuc gauguaucaa uauuaacaau cgaugacgga      660

auauucgaag uuaaagcaac ugcaggagac acacacuuag gaggagaaga uuuugauaac      720

agauuaguaa accacuuugu agaagaauuu aaacgaaaac auaagaaaga cauuucacaa      780

aauaaaaggg cuguaagaag acuaagaaca gcuugcgaaa gagcuaaaag aacacuaagc      840

agcucaacac aagcaagucu agaaauagac aguuuauuug aaggaaucga uuucuacaca      900

ucaauaacaa gagcacgauu ugaagaacua uguagugacc uauuuagaag cacucuagag      960

ccugucgaaa aagcauuaag agaugcuaaa uuagacaaag cacaaauaca cgaucuaguu     1020

cuaguaggag gaucaacucg aauccccaaa guacaaaaac uauuacaaga uuucuucaau     1080

gguagagacc ucaauaaaag uauuaaucca gaugaagcag ucgcauaugg ugcugcagua     1140

caggccgcaa uuuuaauggg ggauaaaucc gaaaacgucc aagaucuauu auuauuagac     1200

guagcaccau uaucacuagg uuuagaaaca gcuggagggg uaaugacugc auuaauaaaa     1260

aggaacagua caauaccgac aaaacaaaca caaauauuua caacauacuc agauaaucaa     1320

ccaggaguuu uaauucaagu auacgaggga gaacgcgcaa ugacaaaaga caacaaucuc     1380

uuaggccggu uugaacuauc agguauaccu ccagccccua gagguguucc acaaauagaa     1440

guaacauuug auauugacgc uaaugguauc cuaaacguca cagcaacuga caaaucaacc     1500

ggaaaagcaa auaaaaucac aauaacaaau gauaagggaa gacuuaguaa agaagaaauc     1560

gaaagaaugg uacaagaggc agaaaaauau aaagcggaag acgaaguaca aagagaaaga     1620

guaagugcua aaaacgcgcu ugaauccuau gcauucaaua ugaaaucagc agucgaggac     1680

gaaggauuaa aaggaaaaau aagugaagca gacaaaaaga aaguuuuaga uaaaugccaa     1740

gaaguuauuu caugguuaga ugcaaauaca uuagcagaaa aagacgaguu cgaacauaaa     1800

aggaaagaac uagaacaagu auguaauccu auaauaagcg gauuauacca aggugcggga     1860

gguccaggac ccggugguuu cggugcucaa ggaccuaaag gcggcagugg aaguggacca     1920

acuauagaag aaguagauua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2447
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt12)

<400>  2447
gggagaaagc uuaccauggc uaaagcagca gcaaucggaa ucgauuuagg gacaacauac       60

agcuguguag gaguauucca acacggaaaa guugaaauaa uagcaaauga ucagggaaac      120

aggacaacuc cuagcuaugu ugcauuuacc gauaccgaac gucucauugg agaugcggca      180

aaaaaucagg uagcauuaaa cccccaaaac acaguauuug acgcuaaaag auuaauagga      240

cgaaaauucg gagauccggu uguacaaagc gacaugaaac acuggccauu ucaaguaaua      300

aaugauggag acaaaccaaa aguccaaguc ucuuacaaag gagaaacaaa agcauucuac      360

ccagaagaaa uaucaaguau ggucuuaacc aaaaugaaag aaauagcaga agcauacuua      420

ggguacccag uaacaaaugc aguaauaaca guucccgcau auuuuaacga uagccaaaga      480

caagcuacua aagacgcagg aguaaucgca ggauuaaaug uacuuagaau uauaaaugag      540

ccaacugcag cagcaauugc auauggauug gacaggacug gaaaaggaga aagaaacgua      600

uuaauauuug accuaggagg aggcacauuu gacguaucaa uauuaaccau agacgacgga      660

auauucgagg uaaaagcaac agcaggagac acccauuuag gaggagaaga uuucgauaau      720

cgauuaguaa aucauuuugu agaagaauuu aaaagaaaac auaaaaaaga uauaucacaa      780

aauaaaagag caguuagacg auuacgaaca gcuugcgaaa gagcaaaaag aacccuaagu      840

ucuagcacac aagcuagccu ugaaauugau ucccuauuug aaggcauaga uuucuauaca      900

agcaucacuc gagcaagauu ugaagaauua ugcagugacu uauuuagauc aacucuagaa      960

ccuguagaaa aagcgcuuag agacgccaaa uuagauaaag cacaaaucca ugauuuaguc     1020

uuaguaggag gaucaaccag aauacccaaa guacaaaaac uauuacaaga cuucuucaac     1080

ggaagagauc uaaauaaauc aauaaauccu gacgaggcag uugccuacgg agccgcggua     1140

caagcagcaa uacuaauggg agacaaaagc gaaaacguac aagaucuauu acuucuagau     1200

guagcaccuc uaaguuuagg auuagaaaca gcaggaggag uaaugaccgc acuaauaaaa     1260

aggaauucaa cgauaccaac aaaacaaacu caaauuuuca caacauacuc agacaaucaa     1320

ccuggaguac uaauacaagu auacgaagga gagagagcaa ugacaaaaga uaacaaucua     1380

uugggaagau ucgaacuauc aggaauaccc ccggcgccac gaggaguacc gcaaauugaa     1440

guaacuuuug auauagaugc caauggaaua uuaaauguaa ccgcaaccga uaaaagcacu     1500

ggaaaagcaa auaaaauaac aauaacaaau gacaaaggaa gacuaucaaa agaagaaaua     1560

gaacgaaugg uccaagaagc agaaaaauac aaagcagaag acgaaguaca acgagaacga     1620

guuucagcca aaaaugcauu agaaucauac gcauuuaaca ugaaaagugc aguagaagac     1680

gaaggacuaa aaggaaaaau cucagaagca gauaaaaaaa aaguacugga uaaaugucaa     1740

gaagucauaa guugguuaga cgcaaauaca uuagcagaaa aagacgaauu cgaacacaaa     1800

agaaaagagc uagaacaagu cuguaacccu auaauaagug gacuauacca aggagcggga     1860

ggaccaggac caggagguuu uggugcacaa gguccaaaag gcggaagcgg cagcggaccu     1920

acaauagaag aaguagauua gggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2448
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt12)

<400>  2448
gggagaaagc uuaccauggc uacagcaaaa ggaauagcua uuggaauaga ucuaggcaca       60

acauacaguu gcguuggcgu uuuucagcau ggaaaaguag aaauuauagc aaaugaucaa      120

ggaaaucgca ccacuccuuc uuauguagcu uucacagaua cagaacgacu uauaggagac      180

gcugcuaaaa accaaguugc aaugaaccca caaaauacug ucuuugacgc aaaaagacua      240

auaggccgaa aauucaauga cccaguagua caagcggaca ugaaacuuug gccauuccaa      300

gugaucaacg aaggugguaa accaaaagua uuaguaucau acaaaggaga aaauaaagca      360

uuuuacccag aagaaauaag cucuauggua cugacuaaau uaaaagaaac agcagaagca      420

uuucuaggac acccaguaac aaaugcagua auaacaguac ccgcuuacuu uaaugacucc      480

caaagacaag caacaaagga cgcaggaguu auagcaggac uuaauguacu uagaauaauc      540

aacgaaccaa cagcggcagc aauagccuau ggauuagaua aaggaggaca aggagaacga      600

cauguauuaa uauuugaccu agguggaggu acauucgaug ucucuauauu aaccauagac      660

gacggaauau ucgaaguaaa agcaacagca ggggacacuc auuuaggcgg agaagauuuu      720

gacaauagau uaguaagcca cuucguagaa gaguucaaaa gaaaacacaa aaaggauaua      780

agucagaaua aacgagcagu aagaagacua cgaacagccu gugaaagagc uaaaagaacg      840

uuaucaaguu caacacaagc aaaucuagaa auagacaguc uauaugaagg aauagauuuc      900

uauaccucaa uaacgagagc uagauuugaa gaacuaugcg cagaucuauu cagaggcaca      960

cuagaaccag uagaaaaagc ucuacgagau gcaaaaaugg acaaagcuaa aauucaugau     1020

auaguccuug uagggggauc aacaagaaua ccaaaaguac aaagauuguu acaagauuac     1080

uuuaacggaa gagauuuaaa caaaucaaua aacccagaug aagcuguagc auauggcgca     1140

gcaguacaag cagcaauacu uaugggagau aaaagugaaa aaguacaaga uuuauuauua     1200

uuagacguag caccacuauc ccuaggacua gaaacagcag gaggaguaau gacagcacuc     1260

auaaaaagaa auaguaccau accaacaaaa caaacccaaa uauuuacaac guauagcgac     1320

aaucaaccag gaguacuaau acaaguguau gaaggagaaa gagcaaugac caaagauaau     1380

aaucuucuug gccgauucga ucucacagga auaccuccag caccaagagg agucccacaa     1440

auugaaguua cauuugacau agacgccaau gguauacuaa acguaacagc uaccgauaaa     1500

aguacaggaa aaguaaacaa aaucacaauc acaaaugaca aagguagauu aucaaaagag     1560

gaaaucgaaa gaaugguauu ggacgcagaa aaauauaaag cagaagacga aguacaaaga     1620

gagaaaauag cagcuaaaaa cgcucuugaa ucauaugcau uuaacaugaa aucaguagua     1680

uccgacgaag gacucaaagg aaaaauaagc gaaucagaua aaaauaaaau acucgauaaa     1740

ugcaacgaac uauuaagcug guuagaagua aaucaacuag cagaaaaaga ugaauuugac     1800

cauaaaagaa aagaacuaga acaaaugugu aauccaauaa uaacuaaauu auaccaagga     1860

ggaugcacag gaccagccug uggcacagga uauguuccug gacgacccgc aacuggacca     1920

acaauagaag aaguugauua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2449
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt12)

<400>  2449
gggagaaagc uuaccaugag cgcaagagga ccagcgauug gaaucgaucu aggaacaacg       60

uacaguugcg ugggaguauu ccaacaugga aaaguugaaa uaaucgcaaa ugaucaggga      120

aauagaacua caccaucaua cguugcuuuu acagacaccg aaagauugau uggagacgca      180

gcgaaaaauc aaguagcaau gaauccaacc aacacaaucu uugacgcaaa aagacucaua      240

ggcagaaaau ucgaagacgc aacgguacag agcgauauga aacacuggcc auuuagagua      300

guaucagaag gaggaaaacc aaaaguacaa gucgaauaua aaggagaaac uaaaacauuu      360

uucccagaag aaauaagcag uaugguauua acaaaaauga aagaaauagc agaagcauau      420

cuaggaggaa aaguucauag ugcaguaaua acuguaccag cauauuuuaa ugauucacaa      480

agacaagcca cgaaagaugc cggaacaaua accggauuaa auguacugag aauaauaaac      540

gaaccaacag cugccgcaau agcauacggg cuagauaaga aaggaugugc cggaggugag      600

aaaaauguau uaauauuuga cuuaggcgga ggaacauuug auguaucaau acuaacaauu      660

gaagacggaa uauucgaagu uaaaaguacg gcgggagaua cacauuuagg aggagaagau      720

uuugauaaca gaaugguaag ucauuuagca gaagaguuca aacgaaaaca caagaaagac      780

auaggaccua auaaaagagc aguaagaaga cuaaggacug caugcgaaag agcaaaaaga      840

acacuaagua gcaguacaca ggcgaguaua gaaauagacu cauuauauga aggagucgau      900

uuuuauacuu caauaacgag agcaagauuc gaagaacuca augcggauuu auuuagagga      960

acauuggaac caguagaaaa agcacuuaga gaugcaaaac uagacaaagg acaaauccaa     1020

gaaauagucc uaguaggugg cucaacaaga auaccaaaaa uccaaaaacu auugcaagau     1080

uucuucaaug gcaaagaauu aaauaaguca aucaauccag acgaagcagu cgcauacgga     1140

gcagcaguuc aagcagcaau auugauaggg gauaaaucag aaaauguaca agaccuauua     1200

uuguuagaug uaacaccauu aagucucggu auagaaacug caggaggagu aaugacaccu     1260

cuaauaaaaa gaaacacaac uauaccaaca aaacaaacac aaacauuuac aacauacagu     1320

gacaaucaau caaguguauu aguacaagua uacgaaggag aaagagcaau gacgaaagac     1380

aacaaucuau uaggaaaauu ugaucuaaca gggauuccuc cagcaccgag agguguacca     1440

caaaucgaag uaacauuuga cauagacgca aauggaauau uaaacguaac agcagcagau     1500

aaaucaaccg ggaaagaaaa caaaaucaca auaacuaacg auaaagggag guuaagcaaa     1560

gaugauaucg aucguauggu ccaagaagca gaaagauaua aaagcgagga ugaggcaaac     1620

agagacagag uagcagcgaa aaaugcauua gaaucuuaca cguauaauau aaaacaaacu     1680

guagaggacg aaaaauuacg gggaaaaaua uccgaacaag auaaaaacaa aauauuagau     1740

aaaugccaag aagucauaaa cugguuagac agaaaucaaa uggcagaaaa agaugaauac     1800

gaacauaaac agaaagaacu agaaagagug uguaauccca uaauaucaaa auuauaccaa     1860

ggagguccag gagguggaag cgggggagga ggaaguggcg caagcggagg gccaacaaua     1920

gaagaaguag auuagggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  2450
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt12)

<400>  2450
gggagaaagc uuaccauguc uguaguagga auagaccucg gauuucaaag uuguuaugua       60

gcagucgcuc gggcaggagg cauugaaaca auugcaaaug aauacucaga cagguguaca      120

ccagcaugca uaaguuucgg accaaaaaac cgaucaauag gcgcagcagc aaaaagccag      180

guaauaucaa augcuaaaaa uacaguacaa ggguuuaaaa gauuccacgg aagagcauuu      240

ucagauccuu uuguagaagc ugaaaaaagu aauuuagccu acgacauagu ucaguuacca      300

acaggauuaa caggcauaaa aguaacuuau auggaagaag aacgaaacuu uacaacugaa      360

caaguaacag caaugcuacu aucuaaauua aaagaaacug cagaaagugu uuuaaaaaaa      420

ccaguaguag acuguguagu aagcgugcca uguuuuuaua cagacgcgga aagaagaucg      480

gucauggaug caacacaaau agcagggcuc aauugccuua ggcucaugaa ugaaacaacu      540

gcaguagcuc uagcuuacgg aauuuauaaa caagacuugc cagcacuaga agagaaacca      600

agaaacgucg uuuucgucga uaugggacac ucagcauacc aaguaagugu uugcgcauuu      660

aauagaggaa aacuaaaagu auuggcaaca gcauuugaca caacacuagg agguagaaaa      720

uucgaugaag uacuagucaa ucacuuuugu gaagaauucg gaaaaaagua caaacuagau      780

auuaaaucaa aaauuagagc auuauugcga cuaagccaag aaugugaaaa acuaaaaaaa      840

uuaaugucag caaaugcauc ugacuuacca uuaagcauug aaugcuuuau gaaugaugua      900

gaugucucag gaacaaugaa ucgaggaaaa uucuuagaaa uguguaacga ucuacuagcu      960

agagucgaac ccccucucag gucagugcua gaacaaacaa aacuaaaaaa agaagauaua     1020

uacgccgugg aaaucguagg uggagcuacc agaauaccag cugugaaaga gaaaauaagu     1080

aaauucuucg gcaaagaauu aucaacaaca cuaaaugcag acgaagcagu uacccgagga     1140

ugugcuuuac aaugugcaau uuuaucgcca gcauucaaag uacgagaauu cucaauaaca     1200

gauguaguac cuuaucccau aucucuuaga uggaauucac cagcagaaga gggaagcuca     1260

gauugcgaag uauuuucaaa aaaccacgcu gcaccguuuu ccaaaguacu gacuuucuac     1320

agaaaagaac cauuuacguu agaagcauac uauucaucuc cccaagacuu accauaccca     1380

gaucccgcca uugcacaauu cucaguacaa aaggugaccc cacaauccga cggauccagc     1440

ucaaaaguga aaguaaaggu aagaguaaau guacacggca uauuuucagu aaguucagcg     1500

ucccucguag aaguucacaa aagcgaagaa aacgaagaac caauggaaac agaccaaaac     1560

gcaaaagaag aagaaaaaau gcaaguagac caagaagaac cccauguaga agaacaacaa     1620

caacaaacac ccgcagaaaa caaagccgaa agugaagaaa uggaaacauc acaagcaggc     1680

aguaaagaua agaaaaugga ucaaccacca caggcaaaaa aagcuaaagu aaaaacaagu     1740

acaguagauc ucccaauuga aaaucaacua cuauggcaaa ucgauagaga gauguuaaac     1800

cuauacaucg aaaaugaagg aaaaaugauc augcaagaca aacuagaaaa agaacggaac     1860

gaugcaaaaa acgcagugga agaguaugua uaugaaaugc gagacaaacu aucaggagaa     1920

uaugaaaaau uuguuagcga ggaugacaga aauucauuca ccuuaaaacu agaagauacu     1980

gaaaauuggu uauaugaaga cggagaagac caaccuaagc aaguguacgu ugauaagcua     2040

gcagagcuca aaaauuuggg ccagccaaua aaaauaagau uccaagaauc cgaagaaaga     2100

ccgaaacuau ucgaagaacu ugggaaacaa auacagcaau acaugaagau aaucucauca     2160

uuuaaaaaca aagaagauca auacgaccac uuagacgcag cagacaugac uaaaguagaa     2220

aaaucuacga acgaagcaau ggaauggaug aauaacaaac uaaaucuuca aaacaaacaa     2280

ucacuuacaa uggacccagu aguaaaaagc aaagaaaucg aagcgaaaau aaaagaauua     2340

acgagcacau guucaccuau aauaucaaaa ccaaaaccaa aaguggaacc accuaaagaa     2400

gaacaaaaaa augcagaaca aaauggaccg guagacgggc aaggagacaa uccaggaccu     2460

caagcagccg aacagggcac agacacagca guaccaucag acagcgacaa aaaacuaccg     2520

gaaauggaca uagacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  2451
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt12)

<400>  2451
gggagaaagc uuaccaugag ugugguagga auagaccuug gauuccuaaa uugcuacaua       60

gcuguagcaa gaucaggagg cauugaaaca auagcaaacg aauauagcga ccgaugcaca      120

ccagcaugca uaucauuagg aaguaggacu agagccauag guaaugcggc aaaaucacaa      180

auaguaacca auguaagaaa caccauacau ggauucaaga aacuacacgg acgcagcuuc      240

gacgauccaa uaguacaaac agaaagaauu agacuacccu acgaacuaca gaaaaugcca      300

aacggaucug caggagucaa aguaagauac cuugaagaag aacggccauu ugcaauugaa      360

caagugacag gaauguuacu ugcaaaacua aaagaaacaa gugaaaaugc auuaaagaaa      420

ccaguagcag auugcguaau uucaauaccc agcuucuuca cagacgcaga aagaagaagu      480

guaauggcag cagcacaagu agccggacua aacugucuaa gacuaaugaa cgaaacaaca      540

gcuguagcuu uagcauacgg cauauauaaa caagaucuac caccacuaga ugaaaaacca      600

agaaacguag uuuuuauaga uaugggacac ucagccuacc aaguccuagu augugcuuuc      660

aacaaaggaa aauuaaaagu acuugcaaca acauuugauc cauaucuagg ggguagaaau      720

uucgacgaag cucuaguaga cuacuuuugu gaugaguuca aaacaaaaua caaaauuaau      780

gucaaagaaa auucaagagc auuacucaga cuuuaccaag aaugcgaaaa auuaaagaaa      840

cuaaugucug caaaugcauc cgauuuaccg cuaaauaucg aaugcuuuau gaaugaucuu      900

gacguaucaa gcaaaaugaa cagagcacaa uuugaacaac uaugugcauc cuuauuagca      960

agaguagaac cuccccuaaa agcgguaaug gaacaagcua aucuccaacg cgaagacaua     1020

agcucaauag aaauaguagg cggagcaacc agaauaccgg cagugaaaga acaaauaaca     1080

aaauuuuucu uaaaagacau uucuacaacu uuaaacgcag acgaagcugu ggcuagaggu     1140

ugcgcacuuc aaugcgccau cuuaucacca gcguucaaag uccgcgaguu caguauaaca     1200

gaccugguac cauacaguau cacgcuccga uggaaaacua gcuuugaaga cggcucuggg     1260

gaaugcgaag uauucuguaa aaaucaccca gcaccauuua gcaaaguaau aacauuucac     1320

aagaaagaac cauucgaacu agaagcauuc uacacaaacu uacaugaagu ucccuaccca     1380

gaugcacgaa uagguaguuu cacaauacaa aauguauucc cacaauccga cggagacuca     1440

ucuaaaguca aagucaaagu gcggguaaac auacauggaa uauucuccgu ugcaagugca     1500

agugugauag aaaaacaaaa ccucgaaggg gaucauucag acgcaccuau ggaaacggaa     1560

acaaguuuca aaaacgaaaa caaagauaau auggacaaaa ugcaaguaga ucaagaagaa     1620

ggacaccaaa aaugccaugc ggaacauacu cccgaagaag aaauagauca uacaggugcu     1680

aaaacaaaau cagcaguauc cgacaaacaa gacaggcuaa aucaaacacu caagaaagga     1740

aaaguaaaaa guauagaccu gccgauacaa agcagucucu gucgacaauu aggacaagau     1800

uuacuaaaua guuacauaga aaaugaaggg aaaaugauua ugcaagauaa auuagaaaaa     1860

gaaaggaacg augccaaaaa ugcuguugaa gaauacguau augacuuucg cgacagauua     1920

ggaacaguau acgaaaaauu uauaaccccc gaagaccuaa guaaacuauc ugcaguacua     1980

gaagacacag aaaauugguu auaugaagau ggagaagauc agccaaaaca aguuuacgua     2040

gauaaacuac aagagcuuaa gaaauacgga caaccaauuc aaaugaaaua uauggaacau     2100

gaagaacgcc cgaaagcauu aaacgacuua ggaaagaaaa uacaauuagu aaugaaagua     2160

auagaggccu acagaaacaa agaugaaagg uaugaccacc ucgaucccac agaaauggaa     2220

aaaguugaaa aaugcauauc agacgcuaug ucauggcuaa acagcaaaau gaacgcccaa     2280

aacaaauuau cacuuacuca ggauccugua guaaaaguaa gcgaaauagu agcgaaaagc     2340

aaagaacuag acaacuuuug uaacccuaua aucuauaaac cuaaacccaa agcagaagua     2400

ccagaggaua aacccaaagc caauucugaa cauaaugggc caauggaugg acaauccggc     2460

acagaaacaa aaucggacag uaccaaagac ucaucacagc acacaaaaag caguggagaa     2520

auggaaguug acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  2452
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt12)

<400>  2452
gggagaaagc uuaccaugaa acucucacua guagcagcga uguuauuacu uuuaagugcu       60

gcacgagcag aggaagaaga uaaaaaagaa gacguaggua caguaguagg uauagaccua      120

ggaacaacau acucaugugu aggaguauuc aagaauggac gaguagaaau uauagcaaau      180

gaucaaggca auagaauaac accaaguuau guagcuuuca cacccgaagg agaaagauua      240

auaggggacg cagcuaaaaa ccaauuaaca agcaauccag agaacacagu auuugacgca      300

aaaagauuaa ucggcagaac auggaaugac cccucuguac aacaagauau uaaauuucua      360

ccguuuaaag ugguagaaaa aaaaacaaaa ccuuauauac aaguagacau aggaggagga      420

caaacgaaaa cauucgcucc agaagaaaua agcgcaaugg uuuuaacuaa aaugaaagaa      480

acagcggaag cauauuuagg aaaaaaagua acucacgcug uaguaacagu cccagcauac      540

uuuaacgaug cucaaagaca agccacaaaa gaugcaggaa caauugcagg cuuaaaugua      600

augagaauaa uaaaugaacc uacagcagcc gcaauagcgu acggacuaga caaaagagaa      660

ggcgaaaaaa acauacuagu auuugauuua ggaggaggaa cauucgaugu aagucuacuu      720

acaauugaca acggagucuu ugaaguagua gccacaaaug gagauacgca ucuaggagga      780

gaggacuucg accaaagggu uauggaacac uucauaaaau uauacaaaaa aaaaacagga      840

aaagacguua gaaaagacaa uagagccgua caaaaauuaa gacgagaggu agaaaaagca      900

aaaagagcau ugucaagcca acaccaagca agaauagaaa uagaaucauu uuaugaagga      960

gaggacuuca gcgaaacacu uacaagagca aaauuugaag aacugaauau ggauuuauuu     1020

agaaguacaa ugaaaccagu ucaaaaaguc uuagaagaua gugauuuaaa aaaaagcgac     1080

auagaugaaa uaguacucgu aggaggauca acaaggauac caaaaauaca acaauuaguu     1140

aaagaguuuu uuaauggaaa agaaccauca cgaggaauaa auccagacga agcaguagca     1200

uacggagcag caguacaggc aggaguacua agcggagauc aagauacagg agaucuaguc     1260

uuacuagaug ucugcccacu uacauuagga aucgaaaccg uaggaggggu aaugacaaaa     1320

cuaauaccac guaacacggu ugugccaaca aaaaaaucac agauauucag uacagcguca     1380

gacaaucagc caaccgucac uauaaaagua uacgaaggag aacgaccacu uacaaaagau     1440

aaccaucuac uaggaaccuu cgauuuaaca ggaauaccac ccgccccaag aggaguacca     1500

caaauagaag uuacauucga aauagacgua aacgguauuc uuagagugac agcugaagac     1560

aaaggaaccg gaaauaaaaa uaaaauaaca auaacuaacg aucaaaaccg acuaacucca     1620

gaagaaauag aacgcauggu aaacgaugca gaaaaauuug cagaagaaga caaaaaacua     1680

aaagaacgaa ucgauacuag aaaugaacua gaaucauacg cauauucauu aaaaaaucaa     1740

auaggcgaca aagaaaaacu aggaggaaaa uuaucaagug aggauaaaga aacuauggaa     1800

aaagcggucg aagaaaaaau agagugguua gaaagucauc aagacgcuga uauagaagau     1860

uuuaaagcaa aaaaaaaaga auuagaagag auaguacaac caauaauauc aaaacuauau     1920

ggaagcgccg guccuccacc aacaggcgaa gaagacacag cugaaaaaga cgaauuauga     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  2453
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt12)

<400>  2453
gggagaaagc uuaccaugca agccccaaga gaauuagcag uuggaauaga ccuagguaca       60

acauacucau guguaggagu uuuucaacaa ggaagaguug agauacuagc aaaugaucaa      120

ggaaacagaa caacacccag cuauguagca uucacugaca cagaaagauu agucggagac      180

gccgcaaaau cacaagcagc ucuaaacccu cauaauacag uuuuugaugc uaaaaggcuu      240

auagggagaa aauucgcaga cacaacagua caaucagaua ugaaacacug gcccuuucga      300

guaguaucag aaggaggaaa accgaaagua agaguuugcu auagaggaga agauaaaaca      360

uuuuacccag aagaaaucuc aucaaugguu cuuaguaaga ugaaagagac agcggaagca      420

uacuuaggac aaccggucaa acacgccguu auaacaguac cugcauauuu caaugacagu      480

caaagacaag cuacaaaaga ugcaggagca auagcaggau uaaauguauu aagaauuauu      540

aaugaaccaa cagccgcagc aauagcauac ggacuagauc guagaggagc cggagaaaga      600

aacgucuuaa uauuugauuu aggaggggga acauuugaug uaucaguucu aucgauagau      660

gcaggaguau uugaaguaaa agcuacagca ggagauacac auuuaggcgg ggaagauuuu      720

gauaacagau uaguaaauca cuucauggaa gaauuuagaa gaaaacacgg uaaggacuua      780

ucaggaaaua aacgagcacu cagaagacuu agaacagccu gugaacgagc aaaacguacu      840

uugagcucaa guacacaagc uacuuuagaa auagacaguu uauucgaagg uguugauuuu      900

uacacaagua uuacuagagc aagauuugaa gaacuauguu cagauuuauu ucguucaaca      960

uuagaaccag uagaaaaagc acuaagagau gcaaaacuag auaaagcuca aauacaugau     1020

guggugcuag uaggagguuc cacaaggauc ccaaaagucc aaaaacuacu acaagauuuc     1080

uuuaauggca aagaacucaa caaaaguaua aaucccgaug aagcaguagc auauggugca     1140

gcaguacaag cagcaguuuu aaugggagau aagugugaaa aaguacaaga uuuacuauua     1200

cuagacguag caccccuauc acucggacua gaaacagcug gaggaguaau gacuacacua     1260

auucaaagaa acgccacaau cccaacaaaa caaacacaaa cauuuacaac auacucagau     1320

aaucaaccag gcguauuuau acagguuuac gaaggugaac gagcaaugac caaagacaau     1380

aaucuacucg guagauucga acuaagugga auaccaccag ccccaagagg aguaccacaa     1440

auagaaguaa cauuugauau agaugcaaau gguauucuca gcguaacugc aaccgaccgu     1500

agcacaggaa aagcuaacaa aauaacuaua acgaaugaua aaggaagacu aaguaaagaa     1560

gaaguagaac gcaugguaca ugaagcagaa caauauaaag cagaagacga agcacaaaga     1620

gauagaguug cagcuaaaaa caguuuagaa gcacaugugu uccauguaaa aggaucauua     1680

caagaagaau cauuaagaga uaaaauucca gaagaagaua gacgaaaaau gcaagauaaa     1740

ugcagagaag uacucgcaug gcuagagcac aaucaauuag cagagaaaga ggaauaugaa     1800

caccagaaac gagaauuaga acaaauuugu cgaccaauau uuaguagguu auacggagga     1860

ccaggagucc caggagguuc aucaugugga acccaagcaa gacaaggaga ucccaguaca     1920

gguccaauaa uagaagaagu ugacuaagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  2454
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt12)

<400>  2454
gggagaaagc uuaccaugca agcuccaaga gaacuagcug uaggaauaga uuuaggaaca       60

acauauaguu guguaggagu auuucaacaa ggaagaguug aaauacuagc aaaugaucaa      120

gggaauagga caacaccauc auauguagca uuuacagaua cagaacgauu aguaggagau      180

gcagcaaaau cacaggcagc ucuaaaccca cauaauacag uauuugaugc aaaaagacua      240

auagguagaa aauuugcaga cacuacagua caaagcgaua ugaaacauug gccauuucaa      300

guaguaucag aagguggcaa accaaaaguc agaguauguu auagaggaga agauaaaacu      360

uuuuaucccg aagaaauauc aucaauggua uuaaguaaaa ugaaagaaac agcagaagca      420

uaucuaggac aaccaguaaa acaugcggua auaacaguuc caacauauuu uucaaacuca      480

caaagacaag caacaaaaga ugccggugca aucgcaggac uuaaaguauu accaauaauu      540

aaugaagcaa cagcagcagc aauagcauau ggacuagaua gaagaggagc uggaaaaaga      600

aauguauuaa uauucgauuu aggaggugga accuuugaug uaucaguauu aagcauagau      660

gcaggaguau uugaagucaa agcaacagca ggagauacac aucuaggagg ggaagauuuc      720

gauaauagau uaguaaauca cuuuauggaa gaguuuagaa gaaaacaugg aaaagauuua      780

agcgguaaua aaagagcauu aagaagacua agaacagcau gcgaaagagc aaaaagaaca      840

ccaucaagca guacgcaagc aacauuagaa auagacucau uauucgaagg aguagacuuu      900

uauaaaucaa uaacaagagc gagauucgaa gaauuaugcu cagacuuauu cagaaguaca      960

cuagaaccag uagaaaaagc auuaagagau gcaaaacuug acaaagcaca aauacaugau     1020

uucguacuag gaggaggauu acacagucau ccacaaggag cugaaguagc agcaggacua     1080

uuacaacgac aaggugcaga acaagaacau caaccauagg gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  2455
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt12)

<400>  2455
gggagaaagc uuaccauguc aaaagguccg gcaguaggaa ucgauuuagg aacaacauau       60

aguugugucg gaguauuuca acauggaaaa guugaaauaa uagcaaacga ucaaggcaau      120

agaacuacac caucuuacgu ugcauuuaca gauacagaaa gauuaauagg ggacgcagcu      180

aaaaaccaag uagcaaugaa cccaacaaau acaguauuug acgcaaaacg acuaauagga      240

agaagauuug augaugccgu uguacaaucu gacaugaaac auuggcccuu uaugguagua      300

aaugacgcag gaagaccaaa aguccaaguc gaauacaaag gagaaacaaa gagcuuuuac      360

ccugaagaag uuucuagcau gguccuaaca aaaaugaaag aaauugcaga agcguaccua      420

ggcaaaaccg uaacaaacgc agucgugaca guaccagcau auuuuaacga uucacaaaga      480

caggcaacaa aagacgcagg aacaauugca ggacucaacg uacuccgaau aauaaaugaa      540

ccaacugcug cagcaaucgc auauggguua gacaagaaag uaggagcaga gcgcaaugua      600

cuaauauuug accuaggagg agguacguuc gauguaagca uauuaacaau agaagauggc      660

auauuugaag uaaaauccac agcaggagac acacacuuag gaggagaaga uuuugacaau      720

agaaugguca accauuucau ugcagaguuc aaaagaaaac acaagaaaga uauuucagaa      780

aauaaaagag caguaagaag auuaagaaca gcuugugaaa gagcuaaaag aacuuuauca      840

ucaucaacac aagcuagcau agaaauugac aguuuauaug aaggaauaga uuucuauaca      900

uccaucacgc gagcaagguu ugaagaauua aaugcagacu uauuucgagg aacacuugac      960

ccuguugaaa aagcccuacg agacgcuaaa cuagacaaaa gccaaauaca ugacauaguu     1020

cuaguaggag gaagcacuag aauacccaaa auacaaaagc uacugcaaga cuucuucaac     1080

ggaaaggaac ucaacaaaag cauuaauccc gaugaagcag uagcuuacgg agcugcagua     1140

caagcugcaa uauuaagugg agacaaaagc gaaaacguac aagaucuacu auuacuagau     1200

guaacaccuc uaagccucgg aauagaaacg gcaggaggag ugaugacagu acucauaaaa     1260

agaaauacua caauaccaac caaacaaaca caaacauuua caacauacuc agacaaucaa     1320

ccaggaguau uaauacaagu auacgaagga gaaagagcca ugacaaaaga caauaaucuc     1380

cuaggaaaau ucgaauuaac aggaauacca ccagcaccuc gcggaguacc acaaaucgaa     1440

guaaccuuug acauugaugc gaacggcaua uuaaauguuu cagccgucga caagucuaca     1500

ggaaaagaga acaagauaac aauaacuaau gauaaagggc gauuaagcaa agaagauaua     1560

gaacgaaugg uacaagaagc agaaaaauau aaagcagaag augaaaaaca aagagauaaa     1620

guaucuagca aaaauagccu agaaaguuau gcauucaaua ugaaagccac aguugaagac     1680

gaaaaauuac aaggcaaaau aaaugacgaa gauaaacaga aaauauuaga caaauguaac     1740

gaaauaauaa acuggcugga uaaaaaucaa acggccgaaa aagaagaauu ugaacaucaa     1800

caaaaagaau uagaaaaagu augcaauccg auaauaacaa aauuauacca aucagcuggg     1860

gguaugccag gggguaugcc agguggauuc ccaggagggg gagcaccacc aagcggagga     1920

gcaagcucag gaccaacaau cgaagaaguc gacuaaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  2456
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt12)

<400>  2456
gggagaaagc uuaccaugau auccgcauca agagcagcag cggcaagauu aguaggagca       60

gcagcaagua gaggaccaac agcagcaaga caccaagaca guuggaaugg uuuaagccau      120

gaagcauuua gacucgugag uaggagagau uaugcaagug aagccauaaa aggagcugug      180

guaggaauag auuuaggaac aacuaauuca uguguugcag uaauggaagg aaaacaggcu      240

aaaguacuag agaaugcgga aggagcuaga accacuccca guguaguagc auucacagcu      300

gauggagaaa gauugguagg gaugccggca aaaagacaag caguuacgaa cccaaauaac      360

acauuuuaug caacaaaacg acuaauaggg aggcgauacg augacccgga aguucaaaaa      420

gauauuaaaa acguuccuuu uaagauagua agagccagca auggagaugc cuggguagaa      480

gcccacggaa aguuauauuc accaagucaa auaggggcuu uuguacuaau gaaaaugaaa      540

gaaacagccg aaaauuacuu aggacauacu gcuaaaaaug caguuauaac aguaccagca      600

uauuuuaaug auagccaaag acaagcuaca aaagaugcag gucagauaag uggucucaac      660

guucugcgcg uaauuaauga accaacagcu gcugcacuag cauacggguu agauaaaagu      720

gaagauaaag ucauagcggu auaugauuua ggaggaggca cauuugauau aucaauauua      780

gaaauacaaa aagggguauu cgaaguuaaa agcaccaaug gagauacguu ucuuggaggg      840

gaagauuuug accaagcguu auuaagacau auagugaaag aauuuaagag agagacagga      900

guagaucuaa caaaagacaa cauggcauua caaagaguua gagaagcugc ugagaaggca      960

aaaugugaau uaagcucaag uguacaaaca gauauaaauu uacccuauuu aacaauggau     1020

agcaguggac cgaaacaucu aaauaugaaa uugaccagag cucaauuuga aggaauagug     1080

acagauuuaa uaaggagaac aauagcacca ugccagaaag caaugcaaga ugcagaggug     1140

aguaaaagcg auaucggaga agugauauug guaggaggaa ugacaagaau gccaaaagua     1200

caacaaacag uacaagacuu auuuggcaga gcaccaagca aagcuguuaa cccagaugaa     1260

gcaguggcua uuggagcagc uauacaagga ggaguguuag caggagaugu aacagaugua     1320

uuauuacuag auguaacacc auuaucauug gguauagaaa cacuaggagg gguauuuaca     1380

aagcuaauaa auagaaauac aacaauacca acaaagaagu cucaaguauu cucaacugca     1440

gcagaugggc aaacacaagu agaaauaaaa guaugucaag gagaaagaga aauggcaggc     1500

gacaauaaac uacuuggaca auuuacacua auaggcauac cgcccgcccc caggggaguu     1560

ccacaaauag aaguaaccuu cgauauagau gccaacggaa uaguacacgu aagcgcaaag     1620

gacaaaggga cagggagaga acaacaaaua guaauacaau ccagcggagg uuuaucaaaa     1680

gacgacauag aaaacauggu uaaaaaugca gagaaguaug cagaagaaga uagaagaaag     1740

aaagaaagag uagaagcagu aaauauggca gaggguauua uacaugauac ggaaacaaaa     1800

auggaagaau uuaaagauca auuaccugca gacgaaugca auaaacuaaa agaagaaaua     1860

agcaaaauga gagaauuacu agcaagaaaa gauucggaaa cuggagaaaa uauaagacaa     1920

gcagcuagua gccugcagca agccagcuua aaacuauucg agauggcaua uaagaaaaug     1980

gcaagcgaaa gagaaggcag ugggagcuca ggaacaggug aacaaaaaga agaccaaaaa     2040

gaagaaaaac aauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  2457
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt12)

<400>  2457
gggagaaagc uuaccauggc ugauaaagaa gcuggagguu cugauggacc acgagaaaca       60

gcuccaacuu cugcuuacuc aaguccagca aggucuuuag gagacacggg aauuaccccg      120

uuaaguccca gucauauagu caacgauacu gauucuaacg uguccgaaca acaaagcuuu      180

cuuguaguag uagcaguuga cuucggaacu acuucaucag gauaugcgua uucauuuaca      240

aaagaaccag aauguaucca cgugaugaga cgaugggaag gaggagaucc cggaguaagc      300

aaucaaaaaa caccgacaac aauacucuua acaccagaac gaaaauucca uucauuuggc      360

uacgcagcua gagauuucua ucaugaucua gauccaaaug aagcaaaaca augguuauau      420

cuugaaaaau uuaaaaugaa acuacauaca acaggugacc ucacaaugga uacugaucua      480

acagcagcaa augggaagaa aguuaaagca cuagaaauau uugcauacgc ccuucaauac      540

uuuaaagaac aagcacuuaa agaacuauca gaucaagcag gaucugaauu ugaaaauagc      600

gauguuagau ggguaauaac aguuccagca auauggaaac aaccagcaaa acaauuuaug      660

cgccaagcug cauaccaagc aggacucgcc ucuccagaga auucagaaca auuaauaauu      720

gcauuagaac cugaagcagc caguauauau ugcagaaaac uaagauuaca ucaaaugauu      780

gaauuaagua guaaagcagc aguaaacggu uauagugguu cagauacagu aggagcuggc      840

uuuacucaag caaaagaaca uauaagaaga aauagacaau caaggacauu uuuaguagaa      900

aauguaauug gugaaauaug guccgaauua gaagaaggag acaaauaugu agucguagac      960

ucugguggcg gaacuguaga ccuaacagua caucaaauaa gacuuccaga aggacaucua     1020

aaagaauuau auaaagcaac gggaggcccc uauggaucau uagguguaga uuaugaauuc     1080

gaaaaauuau uauauaaaau auuuggcgaa gauuuuauag aacaauucaa aauaaaaaga     1140

ccugcggcuu ggguagacuu aaugauagcu uuugaaucaa gaaaaagagc ugccgcccca     1200

gacagaacaa auccauuaaa uauaacauua ccauuuucau uuauugauua uuauaaaaaa     1260

uuuagaggac acucuguaga acaugcacuu agaaaaagca acguagauuu uguaaaaugg     1320

aguucucaag gaauguuaag aaugucacca gacgcaauga acgccuuguu caaaccaacg     1380

auugauagua uaauagaaca cuuacgcgac uuauuucaaa aaccagaagu aucaacaguc     1440

aaauuucuau uuuuagucgg aggauuugca gaagcaccac uucuacaaca agcaguacaa     1500

gcagcauuug gagaucaaug cagaaucaua auaccucaag acguaggccu cacgauucua     1560

aaaggcgcag ugcuauucgg ucuagaucca gcaguuauaa aaguucggcg aucacccuua     1620

acauauggag uuggaguauu aaaucgauac guagaaggaa aacauccacc agaaaaauua     1680

uuaguaaaag acgguacgag augguguacc gauguauucg auaaauuuau aucagcagac     1740

caaucaguag cucucggcga acucguuaaa agauccuaua caccagcaaa accaucucaa     1800

uuaguuauag uaauuaauau auauucaagc gagcacgaua acguuucauu uauaacagau     1860

ccagguguaa aaaagugcgg uacauuaaga cucgacuuaa ccggaacaag uggaacagca     1920

guuccagcac gcagagaaau acaaacauua augcaauuug gugauacuga aauaaaagca     1980

acagccauag acauagccac aucaaaauca guuaaaguug gaauagacuu ucuaaauuac     2040

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  2458
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt12)

<400>  2458
gggagaaagc uuaccauguu agcaguacca gaaaugggau uacagggacu auauauugga       60

ucuucuccag aaagaucacc aguaccauca ccacccgggu caccaagaac ccaagaaagc      120

uguggaauag cuccacuaac accaucacaa uccccuaaac cagaaguaag ggcaccccaa      180

caagccaguu ucaguguugu aguagcaaua gauuuuggaa cuacaucauc agguuacgca      240

uuuuccuuug caucagaucc ugaagcaauu cauaugauga gaaaauggga aggaggagac      300

ccuggcguag cacaucagaa aacuccuaca uguuuacuuu ugacaccaga aggagcauuu      360

cauucauuug gauauacagc acgagauuau uaucacgacu uagauccaga agaagcuaga      420

gauuggcucu acuuugaaaa auuuaaaaug aaaauacaua gugcaacaga ucuaacauua      480

aaaacccaau uagaagcugu uaaugguaaa acuaugccag cgcuagaagu auuugcgcac      540

gcauuaagau uuuuccgaga acaugcauua caagaacuua gagaacaauc accuucacua      600

ccugaaaaag auacaguuag auggguauug acuguaccgg caauauggaa acaaccagcg      660

aaacaauuua ugagagaagc ugcauauuua gcuggguuag uaucacgaga aaaugcagag      720

caacucuuaa uugcgcuuga gccagaagca gcaucugucu acugcagaaa auuaagacua      780

caucaacuac uagauuuaag uggcagagca cccggaggug gaagacuagg ugagcgaaga      840

agcauagauu caaguuuccg acaagcaaga gagcaacuaa gacgaucaag acacucaaga      900

acauuucuag uagaaagcgg uguaggagaa uuaugggcag aaaugcaagc aggagaucga      960

uauguaguug ccgauugcgg ggguggcaca guagauuuaa caguccauca acuagaacaa     1020

ccacacggaa cucuaaaaga acuauauaaa gcaucaggag guccauacgg cgcaguagga     1080

guggacuuag cguucgaaca acuacuaugc agaauauuug gagaagauuu uauagcgaca     1140

uuuaaaagac aaagaccugc ggccugggua gaucuaacaa uagcauucga agcaagaaaa     1200

cggacggccg ggccgcauag agcaggagcu cuaaauauaa gccuaccauu uucauuuaua     1260

gacuuuuaua gaaaacagag aggacauaac guugaaacug cacugagacg auccucagua     1320

aauuucguaa aauggucuuc acaaggaaug uugcgaauga gcugcgaagc aaugaaugaa     1380

cuauuucaac caacuguaag uggcauuauu caacauauag aagcacuauu agcaagaccu     1440

gaaguccaag gaguuaaacu gcuauuccug guagguggau uugcagaauc ggcaguauua     1500

cagcaugcag uacaagcagc uuuaggugca agaggauuac gaguaguagu accacaugau     1560

guaggacuaa caauuuuaaa aggagcugua cuauucggcc aagcuccagg aguuguaaga     1620

guuagaagaa guccauuaac cuacggggua gggguacuua auagauucgu accuggacga     1680

cauccaccag aaaaauuauu aguaagggau ggaagacgcu gguguacaga uguguucgaa     1740

agauucguag cugcugaaca gagcguugcu cuaggggaag aaguacgaag aucauacugu     1800

ccagcuagac caggccaaag gcgaguauua auaaauuuau auuguugugc agcagaagau     1860

gcaagauuca ucacugaucc aggaguuaga aaaugcggag cacucucucu agaguuagaa     1920

ccugcggacu guggacaaga caccgcagga gccccaccag gaaggagaga aauacgagca     1980

gcaaugcaau uuggugauac agaaauuaaa gucacugcag uagauguauc gacaaauaga     2040

ucaguaagag cuucgauuga uuuccuuucg aauuaaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  2459
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt12)

<400>  2459
gggagaaagc uuaccauggc ucgagaaaug acaauuuuag gaucagcggu auugacacuu       60

uuauuagcag gauaccuagc ccaacaauac cuaccacuac cuacaccaaa agugauagga      120

auagaccuug gaacaacaua cuguucagua ggaguauucu uuccaggaac agguaaagua      180

aaaguaauac cagaugaaaa cggacacaua aguauacccu caaugguaag uuuuaccgau      240

aacgauguau acguaggaua cgaaucaguu gaauuagcag acucaaaucc acaaaacaca      300

auauaugacg caaaaagauu uaucggaaaa aucuucacag cagaggaauu agaagcagaa      360

auaggaagau aucccuucaa aguauuaaau aaaaacggaa ugguagaauu cucugucaca      420

ucaaacgaaa caauaacagu aagcccagaa uacguaggca gucgauuacu acuaaaacuc      480

aaagaaaugg cagaagcgua cuuaggaaug ccaguagcaa augccguaau aucaguccca      540

gcagaauucg aucuaaaaca acgaaacagc accauagaag cagccaaucu agcaggauua      600

aaaauacuaa gaguaauaaa cgaaccaacc gcagcagcca uggcauaugg acuacacaaa      660

gcagauguau uucacguauu aguaauugau cuaggaggcg gaaccuuaga cguaucauua      720

uuaaauaaac aaggaggaau guucuuaacu agagccaugu caggaaauaa caaacuagga      780

ggacaagauu uuaaccaacg acucuuacaa uacuuauaca aacaaauaua ucaaacauau      840

ggauuuguuc cuagcagaaa agaagaaaua cauagacuaa gacaagccgu agaaaugguu      900

aaauuaaauc uuacacucca ccaaagugca caacuaagcg uguuacuaac aguagaagaa      960

caagacagaa aagaaccaca cucuucagac acagaauuac caaaggauaa auuaucauca     1020

gcagaugacc accgaguaaa uucaggauuc ggaagaggac uaucagauaa aaaaucagga     1080

gaaucacaag uucuauucga aacagaaaua ucaagaaaac uauuugacac auuaaacgaa     1140

gauuuauucc aaaaaauacu aguaccaaua caacaaguac uuaaagaagg acaucuugaa     1200

aaaacggaaa uagacgaagu aguacucgua ggagguucaa caagaauacc aagaauaaga     1260

caaguaauuc aagaauuuuu uggaaaagac ccaaauacau ccguagaucc agaucuagcc     1320

guaguaaccg gcguagcuau acaagcagga auagauggug gaucauggcc auuacaagua     1380

ucagcacucg aaaucccaaa caagcacuua caaaaaacaa auuucaacua aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2460
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt12)

<400>  2460
gggagaaagc uuaccauggc agcaaucgga guucaucuag gauguacaag cgcaugcgua       60

gcaguauaca aagacggucg agcagguguu gucgcaaacg augcaggaga uagaguaaca      120

ccagcuguag uagcauauag ugaaaacgaa gaaauaguag gauuagcagc aaaacaaagc      180

aggauucgaa auauaucaaa uacaguaaug aaaguaaaac aaauauuagg ccgaagcagc      240

uccgacccuc aagcacaaaa auauauagca gaaaguaaau guuuaguaau agaaaaaaau      300

ggaaaacuaa gauacgaaau ugauacggga gaagaaacaa aauucguaaa uccggaagau      360

guagcaaggc uaauauuuag caaaaugaaa gaaacagcuc auaguguauu aggaagcgac      420

gcaaacgacg uaguuauaac agucccuuuc gauuuuggag aaaaacaaaa aaaugcucuu      480

ggagaagccg caagagcagc cggcuuuaau guacuaagac uaauacauga accaucagca      540

gcucuauuag cauauggaau cggacaagau ucaccaacag guaaaaguaa cauacuagua      600

uuuaaauuag gaggaacauc auuaucacua uccguaaugg aaguaaauuc aggaaucuau      660

agaguauuaa guacaaacac agacgacaac auuggaggag cacacuuuac agaaacuuua      720

gcacaauauc uugcauccga auuucaaaga aguuuuaaac augacguaag agguaacgca      780

agagcgauga ugaaacugac aaauucagca gaaguagcaa aacauagucu aucaacauua      840

ggauccgcaa acugcuuucu agauaguuua uaugaaggac aagacuuuga cugcaaugua      900

ucaagagcac guuucgaacu cuuauguuca ccguuauuua auaaaugcau agaagcaaua      960

agaggacuau uagaucaaaa uggauuuaca gcugaugaua uaaauaaagu uguguuaugu     1020

ggaggaucau caagaauacc aaaauuacaa caauuaauaa aagauuuauu ucccgcagua     1080

gaauuauuaa auucaauacc accagacgaa guaauuccaa uaggcgcagc caucgaagca     1140

ggcauacuaa uaggaaaaga aaaccuauua guagaagacu cauuaaugau agaauguuca     1200

gcaagagaua uauuaguaaa aggaguagau gaaaguggug cgucaagguu uacaguauua     1260

uuuccaagcg gaacaccacu accugcaaga agacaacaua cgcuacaagc accagguagu     1320

auaaguucag uaugucuaga acuauaugaa uccgacggaa aaaacagcgc aaaagaagaa     1380

acaaaauuug cacaaguugu uuuacaagau uuagauaaaa aagaaaacgg cuuaagagac     1440

auuuuagcag uauuaacaau gaaacgcgau ggaucacuac auguaacaug uacagaccaa     1500

gaaacaggaa aaugcgaagc aauaaguaua gaaauagcuu cauaaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  2461
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt12)

<400>  2461
gggagaaagc uuaccauguc aguaguagga cuugauguag gaucacaauc auguuacaua       60

gcaguagcua gagccggugg gauagaaaca auagcaaacg aauuuaguga uagaugcaca      120

ccaaguguca uaucauuugg uagcaaaaac agaacaauag gaguagcagc gaaaaaccaa      180

caaauaaccc acgcaaacaa cacaguauca aacuucaaaa gauuccacgg cagagcauuu      240

aacgaccccu ucauacaaaa agaaaaggaa aacuugaguu augacuuagu accacucaaa      300

aauggaggag uuggaauaaa aguaauguac augggggaag aacacuuauu uagcguagaa      360

caaauuacug caaugcuauu aacaaaacuu aaagaaacag cagaaaacuc auuaaagaaa      420

ccaguaacag auuguguaau cuccguacca ucuuucuuua cagaugcaga aagacgaucc      480

gucuuagacg cagcacaaau aguuggccua aauuguuuaa gguugaugaa cgacaugacu      540

gccguagccc uaaauuaugg uauuuacaaa caagacuuac caagccucga ugagaaaccc      600

cggauaguag uauuuguaga caugggacac agcgcauuuc aagugagugc cugugccuuu      660

aacaaaggaa aacucaaagu ucucgguacc gccuuugauc cguuuuuagg aggcaaaaau      720

uucgacgaaa aauuagucga acauuuuugc gcagaauuua aaacaaaaua uaaauuagac      780

gcgaaaagca aaauaagagc gcuacugaga uuauaccaag aaugugaaaa acuaaagaaa      840

cuaaugaguu caaauaguac agaccuacca cuaaauauag aguguuucau gaacgacaaa      900

gacguaagcg gaaaaaugaa uagaucacag uucgaagaac uuugugcaga acuauuacag      960

aaaauagaag uucccuuaua uucauuauua gaacaaacac acuuaaaagu agaggauguc     1020

ucagcuguag aaaucgucgg aggagccacc cguauuccag cggucaaaga aagaauagca     1080

aaauucuuug gcaaagacau aaguacaacc cuaaacgccg augaagcagu cgcaagagga     1140

ugugcacucc aaugugcaau ccuuagucca gccuuuaaag uaagagaguu uuccguaacu     1200

gacgcaguac cauuuccuau uucucuaauu uggaaucaug auucagaaga uacagaagga     1260

guacaugaag uauuuucaag aaaccaugca gcaccguuca guaaaguauu gacauuuuug     1320

cgaagaggcc cauucgaacu agaagcauuu uacucagauc cacaaggggu accauacccc     1380

gaagcaaaaa ucggaagauu uguuguacaa aacgucucag cacaaaaaga uggagagaaa     1440

agcagaguaa aaguaaaagu acgaguaaac acucauggaa uauucacaau aucuaccgca     1500

agcaugguag aaaaaguccc aacagaagaa aacgaaaugu caagcgaagc cgauauggaa     1560

ugcuugaauc aacgaccgcc cgaaaaccca gauacugaca aaaacguaca acaagauaau     1620

ucagaagcug gaacucaacc acagguacaa accgaugcac aacaaaccuc acaaagccca     1680

ccaagucccg aacuuacguc cgaagaaaac aaaauaccag acgcagauaa agcaaacgag     1740

aagaaagucg accaaccacc agaagcaaag aaaccgaaaa uaaaaguagu gaauguagaa     1800

uuaccaauag aagccaaccu aguguggcaa cuaggaaaag accuccuaaa cauguacauu     1860

gaaacagaag gaaaaaugau aaugcaagau aaauuggaga aagaaagaaa cgacgccaaa     1920

aaugcaguag aagaauacgu cuacgaguuc agagauaaac uauguggucc auaugaaaaa     1980

uucauaugug aacaagauca ccaaaauuuc cuuagauuac uuacagaaac ugaagauugg     2040

uuauaugaag aaggcgaaga ucaagcaaaa caagccuacg ucgacaaauu agaagaauua     2100

augaaaauag gaacaccagu gaaaguaaga uuccaagaag cagaagaaag accaaaaaug     2160

uuugaagaau uaggucagcg cuuacaacau uacgccaaaa uugcagcaga uuuuagaaau     2220

aaagaugaaa aauauaacca uauugacgaa ucagagauga agaaaguaga aaaaucaguc     2280

aaugaaguaa uggaauggau gaauaaugua augaacgcuc aagcaaagaa aucauuagac     2340

caagacccag uagugagagc ccaagaaaua aaaacaaaaa uaaaagaauu aaauaauaca     2400

ugugaaccug uuguuacaca accaaaacca aaaauagaaa guccaaaacu agaacgaacg     2460

ccaaacggac caaauauaga caagaaagaa gaagaucuag aagacaaaaa uaacuucggu     2520

gcagaaccuc cacaucaaaa cggagaaugu uacccaaacg agaaaaacag uguaaacaug     2580

gacuuagacu aaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  2462
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt12)

<400>  2462
gggagaaagc uuaccauggc cgauaaagua aggcgccaac guccaagaag aagaguaugu       60

ugggcacuug uugcaguucu acuugcagac uuauuagcac uaagugauac acuugcagug      120

augaguguag aucuuggauc cgaaagcaug aaaguagcaa ucguaaaacc cggaguacca      180

auggaaauug uacucaacaa agaaagucga agaaaaacac caguaaucgu aacucuaaaa      240

gaaaaugaaa gauuuuucgg ggauucugca gcaucuaugg caauuaaaaa cccaaaagcu      300

acauuacguu acuuccaaca uuuacuuggu aagcaagcag auaacccuca cguugcucua      360

uaucaggcuc guuucccaga acaugaacuc acauucgacc cacaacgaca gacaguacac      420

uuucaaauau caagccaauu acaauucuca ccagaagaag uacuagguau gguacuaaac      480

uauucgcgaa guuuagcaga agacuucgcu gaacaaccaa uaaaagaugc cguaauaaca      540

gucccagucu ucuuuaacca agcagaaagg agagccguuc uacaagcggc uagaauggca      600

ggauuaaaag uauugcaacu aauaaaugac aauacugcga ccgcccuaag uuacggcguu      660

uuucgaagaa aagauauaaa uacaacagcc caaaacauaa uguucuacga caugggaagu      720

ggaucaacag uaugcacuau aguuacauac caaaugguaa aaacgaagga agcaggaaug      780

caaccacagc uacaaauaag aggaguagga uuugaucgua cacuaggagg auuagaaaug      840

gaacuaagac uuagagaacg cuuagcagga uuguucaaug aacaaagaaa gggccaacgc      900

gccaaggaug ugagagagaa uccaagagca auggcaaaau uacucagaga ggccaaccgg      960

uuaaaaacag uguuaucagc aaacgcagau cauauggcuc agauagaagg acugauggau     1020

gacguugauu ucaaagcaaa agucacacga guugaauuug aagaguuaug ugcagauuua     1080

uucgaaagag uuccuggacc uguucaacaa gcgcuacaaa gugcagaaau gaguuuagau     1140

gagauugaac aagugauucu aguuggcgga gcaacucgag uuccaagagu ccaagaagua     1200

cuguuaaaag ccguaggcaa agaagaauua gguaaaaaua uaaaugccga ugaagcagcc     1260

gcaaugggag ccguuuauca agcugcugcc uuaucgaaag cauuuaaagu aaaaccauuu     1320

guuguaaggg acgccguggu auacccaaua uuagucgagu uuacacgaga agucgaagaa     1380

gaacccggaa uacauucauu aaaacauaac aaacgaguuc uauuuucaag aauggggccg     1440

uauccacaaa gaaaaguaau aaccuuuaau agauacuccc acgauuuuaa uuuccacauu     1500

aauuauggag aucuaggauu uuuagguccg gaagaucuuc guguauuugg gucacaaaau     1560

uugacaacag ucaaacuaaa aggagucgga gacucauuua agaaauaucc agauuaugaa     1620

ucaaaaggaa uuaaagcuca uuucaauuug gaugaaagug gaguacucag ucuagauagg     1680

guagaaagcg uauuugaaac auuagucgaa gacucagcag aagaagaaag cacucugacu     1740

aaacuaggaa auacaauauc aucacuauuc ggagguggga cgaccccaga ugcaaaagaa     1800

aauggaacag auacuguaca ggaagaagaa gaaucaccag cagaaggaag caaggaugaa     1860

ccaggugagc aaguagaacu aaaagaagaa gcagaagcac caguagaaga cggaagucaa     1920

ccaccuccac cagaaccuaa aggagacgcg accccagaag gagaaaaagc uacagaaaag     1980

gaaaauggag auaaaucaga agcucaaaaa ccgucagaaa aagcugaagc aggaccagaa     2040

ggcguugccc cagcaccgga gggagaaaag aaacaaaaac cagcaagaaa aagaagaaug     2100

guggaagaaa ucgguguaga gcuaguagua uuagacuuac cugacuuacc agaagauaaa     2160

uuggcucaau ccguucaaaa acuucaagau cuaacacuua gagacuuaga aaaacaagaa     2220

cgagaaaaag cagcaaacuc acuagaagca uuuauauucg aaacacagga uaaacuauac     2280

caaccagaau accaagaggu uucaacugag gaacaaaggg aagagaucuc aggaaaacuc     2340

agugcagcca guacaugguu ggaagacgaa ggaguaggcg caacaacggu cauguuaaaa     2400

gaaaaacuag cggaacuuag aaaauuaugc caaggauuau uuuucagagu ugaagaaaga     2460

aagaaauggc cagaaagauu auccgcuuug gauaauuuau uaaaucauuc aucaauguuu     2520

cuaaaaggcg caagauuaau accugaaaug gaucaaauau ucacagaagu agaaaugacu     2580

acauuagaaa aaguaauaaa ugaaacuugg gcuuggaaaa augcuacacu agcagaacaa     2640

gcaaaauuac cagcuaccga aaaaccagua cuacuaucaa aagacauaga ggcaaaaaug     2700

auggcccuag acagagaagu ucaauaucua cuaaauaaag caaaauuuac uaaaccuaga     2760

ccaagaccua aagauaaaaa ugguacacga gcugagccuc cacucaaugc guccgcaucc     2820

gaucaaggag aaaaaguuau acccccugcc ggacaaacag aagacgcaga gccaaucuca     2880

gaaccagaaa aaguggaaac aggaagugaa ccuggagaca cagaaccacu agaacucgga     2940

gguccggggg cagaaccaga acaaaaagaa cagaguacag gacaaaaacg accgcuaaag     3000

aaugaugagu uauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2463
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt12)

<400>  2463
gggagaaagc uuaccaugcc agaggaaacc caaacucaag aucaaccaau ggaagaagaa       60

gaaguagaaa cauuugcuuu ccaagccgaa auagcacaac ugaugucacu aauaauaaau      120

acauuuuauu caaacaagga aauuuucuug agagaacuca uaaguaacuc aagcgacgca      180

cucgacaaaa uaagauacga aagccuaaca gacccgucua aacuggacuc aggaaaagag      240

cuacauauaa accuaauacc uaacaaacaa gauagaacac uaaccauagu agauacagga      300

auagguauga caaaagcaga uuuaauaaac aaccuaggca caauagccaa guccggaacc      360

aaagcguuca uggaagcgcu ccaagccggc gcagauauca gcaugauagg acaauucggg      420

guaggauucu acucagcaua ucuaguagca gaaaaaguaa cgguuaucac caaacauaau      480

gacgacgaac aguacgcaug ggaaaguucg gcaggcggcu cauucacagu cagaaccgac      540

accggggaac caaugggaag agguacaaag guaauacuac accuuaaaga agaccaaaca      600

gaauaccuag aagaaaggag aauaaaagaa auaguaaaaa aacacucaca auucauugga      660

uacccaauaa cauuauuugu agaaaaagaa agagacaaag aaguaagcga cgaugaagca      720

gaagaaaaag aagauaaaga agaagagaaa gaaaaagaag agaaagaaag ugaagacaaa      780

ccagaaauag aagacguugg cucggaugaa gaagaagaaa aaaaagacgg agauaaaaaa      840

aaaaaaaaaa aaauaaaaga aaaguacaua gaucaagaag aacucaauaa aacaaagcca      900

auauggacac gaaauccaga ugacauaacu aacgaagaau acggcgaauu uuauaaaagu      960

uuaacaaacg acugggaaga ccaucucgca guaaaacauu uuucaguaga aggacaacua     1020

gaauucagag cacuauuauu cguccccaga agagcaccau uugauuuauu ugaaaauaga     1080

aaaaaaaaaa acaacauuaa acuauaugua agaagaguuu ucauaaugga caauugugaa     1140

gaauuaauac cagaauaucu aaacuuuaua agaggggugg uugacagcga agauuuaccg     1200

cuuaacauaa gccgagaaau guugcaacag aguaaaauac uaaaaguaau aagaaaaaau     1260

cuaguaaaaa aauguuuaga auuauuuacg gaauuagcag aggacaaaga aaacuacaag     1320

aaauuuuacg aacaauucag uaaaaacaua aaauuaggca uacacgaaga cagucaaaau     1380

agaaagaaac uaucagaacu acuaagauau uacacaagug caaguggaga ugaaauggua     1440

agcuuaaaag acuacuguac aagaaugaag gaaaaccaaa aacauauaua uuauauaaca     1500

ggagaaacaa aagaucaagu agcaaacagu gccuucguag aaagacuaag aaaacauggg     1560

cuagaaguaa uauacaugau agaaccuaua gaugaauauu gcguacaaca acuaaaagaa     1620

uuugaaggaa aaacccuagu aucgguaaca aaggaaggau uagaauuacc cgaagaugaa     1680

gaagaaaaaa agaaacaaga agaaaaaaaa acaaaauucg aaaaccuaug caaaauaaug     1740

aaagauauac uagaaaaaaa aguugaaaaa guugugguau cuaacagauu aguaacuuca     1800

ccaugcugca ucguaacuag uacguauggc uggacagcaa acauggaaag aauaaugaaa     1860

gcacaggcuu ugagagauaa caguaccaug ggauauaugg cagcaaaaaa acaucuagaa     1920

auuaauccag accacaguau aauagaaacg uuaagacaga aagcagaagc ggacaagaac     1980

gacaaaucag uaaaagaccu cguuauacua cucuaugaaa cagcacuacu aagcagugga     2040

uuuucauuag aagauccaca gacacacgca aacaggauuu auagaaugau uaaacuugga     2100

cucggaauag acgaagauga cccaacagca gaugacacaa gugcagcagu gaccgaagaa     2160

augccaccgu uagaagggga ugacgacacu aguagaaugg aagaaguaga uuaaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  2464
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt12)

<400>  2464
gggagaaagc uuaccaugga cagcucaaaa cuagacucag gaaaaggacu acacauaaac       60

cuaguaccaa acaaacaaaa ccaaacacua acaauaguag acacaagaau aggaaugaca      120

aaaacagacc uaauaaacaa ccuaggaaca guaacaaaaa gcggaacaaa agcauuuaug      180

gaagcacuac aagcagacgc agacauaagc augauaggac acuucggagu aggauucuac      240

ucagcauacc uaguagcaaa aaaaguaaca guaauaucaa aacacaacaa cgacgaacaa      300

uacacauggg aaucaagcgc aggaggaagc uucacaguaa gaacagacga auaaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  2465
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt12)

<400>  2465
gggagaaagc uuaccaugcc agaagaagua caccauggag aagaagaggu agaaacauuc       60

gcauuucaag cagagauugc acaacuaaug aguuugauaa uaaauacauu uuauagcaac      120

aaagaaauau uuuuaagaga acuaauuucu aacgcaagcg acgcauuaga caaaauacga      180

uaugagaguc uaacugaucc aaguaaacua gauaguggaa aggaacuuaa aauagacaua      240

auaccgaauc cacaagaacg aacauugaca cuaguggaca caggcauagg aaugacaaag      300

gccgaucuaa uaaauaaucu uggcacaaua gcaaaaagug ggacuaaagc guuuauggag      360

gcacuacaag cgggagcaga uauaaguaug auaggacaau uuggaguugg auuuuauuca      420

gcauacuuag uggcagaaaa aguugucgua auaacaaaac auaacgauga cgaacaauac      480

gccugggaau caagcgcagg aggaaguuuu acaguaagag cagaccacgg ugaaccaauc      540

ggaaggggaa caaaaguaau acuacacuua aaagaagauc aaacagagua uuuggaagaa      600

cgaaggguaa aagaaguagu aaaaaaacac ucacaauuua uaggauaucc gauaacauug      660

uaccuagaaa aggaaaggga aaaagaaaua agcgaugacg aagcagaaga agaaaaaggg      720

gaaaaggaag aagaagauaa agacgaugaa gaaaaaccaa aaauagagga cguaggaagu      780

gaugaagaag augacucagg aaaagauaaa aaaaaaaaaa cuaaaaaaau caaagaaaaa      840

uacauagauc aagaagaauu aaauaaaaca aagccaauau ggaccagaaa cccagacgac      900

auaacacaag aagaauaugg cgaauucuau aaaagucuaa caaaugacug ggaagaccac      960

cuagcaguaa aacacuucag cgucgaaggu caauuagaau ucagagcucu acuauuuaua     1020

ccaagaagag caccauucga ucuauucgaa aacaaaaaaa aaaaaaauaa uauaaaacuc     1080

uacguccgca gagucuuuau aauggacucg ugcgacgaac uaaucccaga auauuuaaac     1140

uuuaucagag ggguaguaga cucagaggac cucccacuaa acauaagcag ggaaaugcuu     1200

caacaaagca aaauccuaaa gguaaucaga aaaaauaucg ucaaaaaaug ccucgaacua     1260

uuuucagaau uagccgaaga uaaagaaaac uacaaaaaau uuuacgaagc auucagcaaa     1320

aauuuaaaac uaggcauaca cgaagacucc acaaacagaa gaagauuaag cgaauuacua     1380

agauaucaca caucacaguc gggagaugaa augacaucuu uaucagagua cguaagccga     1440

augaaagaaa cacaaaaaag uauauacuau aucacuggag aaaguaaaga acaaguagcg     1500

aacucagcau uuguagaacg uguaagaaaa cgaggauuug aaguaguaua caugacagaa     1560

ccaauugacg aauacugugu ccaacaauua aaagaauucg augguaaaag uuuaguuuca     1620

guaacaaaag aaggauuaga auuaccugaa gacgaagaag aaaagaaaaa aauggaagaa     1680

agcaaagcaa aauuugaaaa ucuaugcaaa cucaugaaag aaauauuaga caaaaaagug     1740

gaaaaaguca cgauuuccaa cagacucgua agcucacccu guugcauagu aacaucuaca     1800

uaugguugga cugcaaacau ggaaagaaua augaaagcac aagcuuugag agacaauuca     1860

acaaugggau auaugauggc aaagaaacau uuagaaauaa acccagacca uccaaucgua     1920

gaaacacuga gacaaaaggc agaagcagac aaaaaugaua aggccgugaa agaucuugug     1980

guacuucuau ucgaaacagc ccuacugagu aguggauuca guuuagaaga cccacaaaca     2040

cacuccaaua gaaucuaucg aaugaucaaa cuaggauuag gaauagacga ggaugaagua     2100

gcugcagaag aaccaaaugc agcaguacca gaugaaauac caccgcuaga aggagaugaa     2160

gaugcgagcc gcauggaaga aguagacuag ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  2466
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt12)

<400>  2466
gggagaaagc uuaccaugag agcacugugg guauuaggau uaugcugcgu auuacuaacg       60

uuuggaucag ugagagcaga ugaugaaguc gauguugaug gaacaguaga ggaagaccuc      120

gguaaaagua gagaaggcuc aagaacugac gacgaaguug uucaaagaga agaagaagcg      180

auacaauuag auggauuaaa ugcaucacaa auaagagaac uucgugaaaa aucagaaaaa      240

uuugcguuuc aagcagaagu aaacagaaug augaaacuaa uaauaaauuc auuauacaaa      300

aauaaagaaa uauuuuuaag agaacuuauu ucaaacgcaa gcgaugcauu ggauaaaaua      360

agauugauaa gucuaacaga ugaaaacgcc uuaucaggaa augaagaauu aacaguaaaa      420

auaaaaugcg auaaagagaa aaauuuacua cauguaacug acacgggagu aggaaugaca      480

agagaagaau uagucaaaaa uuugggaaca auagccaaau caggaaccuc agaauuucua      540

aacaaaauga cugaagcaca agaagacggg caaucaacaa gugaauuaau aggacaauuu      600

gggguaggau ucuacagugc guuuuuagua gcggacaagg uaauaguaac caguaaacau      660

aauaacgaca cacaacauau augggaguca gacaguaacg aguucagugu aaucgcagac      720

ccgagaggua acacauuggg acgaggaaca acuauaacgu uaguacucaa agaagaggcu      780

ucagauuacc uagaacugga uacaauaaag aaucucguga agaaauauuc ccaauucauc      840

aacuucccaa uauacguaug gaguucaaaa acagaaacag uggaggaacc aauggaagaa      900

gaagaagcag cuaaagaaga gaaagaagaa ucagaugaug aagcugcagu cgaagaagaa      960

gaagaagaaa agaaaccgaa aacuaagaaa guagagaaaa caguuuggga uugggaacua     1020

augaacgaca uaaaaccaau uuggcaacga ccgucaaaag aaguggaaga ggaugaauau     1080

aaagcauuuu acaaaucauu cucuaaagaa ucagaugauc caauggcaua uauacauuuu     1140

acagcagaag gggaaguaac auuuaaguca auccuauuug uaccaaccuc agcaccgagg     1200

ggauuauucg acgaauaugg aagcaagaaa ucggauuaua uaaaacuaua uguaagaagg     1260

guauuuauaa ccgaugauuu ccacgauaug augcccaaau aucuaaauuu uguaaaagga     1320

guaguagaca gcgacgaucu accauuaaau guaucucgag aaacacucca acagcauaaa     1380

cuccuaaaag uuauaaggaa gaaauuaguc aggaaaacac ucgauaugau aaagaaaaua     1440

gcagaugaua aauauaacga cacauuuugg aaagaauuug guacaaauau uaaauuagga     1500

guaaucgaag aucacaguaa cagaacgaga uuagcaaaac uauugagauu ucaaaguuca     1560

caccacccaa cagauauaac uagcuuagac caauaugugg aaaggaugaa agaaaaacaa     1620

gauaaaauuu auuuuauggc agggaguagu aggaaagaag cugaaaguag ccccuucgug     1680

gaaagauuau uaaagaaagg auaugaagua auauaucuaa cagaaccagu agacgaauau     1740

uguauacaag cacuaccaga guucgacgga aaaagauuuc aaaauguagc caaagaagga     1800

guaaaauuug acgagucaga gaaaacaaaa gaaagcagag aagcaguaga aaaagaauuu     1860

gaaccucuac uuaacuggau gaaagauaag gcuuuaaaag auaaaauaga aaaagcagua     1920

guaagccaaa gacuuacaga aucaccaugu gcauugguag caagucaaua uggauggagu     1980

ggaaacaugg aaaggauaau gaaagcacaa gcguaccaaa caggaaaaga uauaucaacg     2040

aauuacuaug ccagccagaa aaagacauuc gaaauaaauc caagacaccc auuaauaaga     2100

gacauguuaa gaagaauuaa agaagaugaa gaugauaaaa cuguauuaga ccuugcagua     2160

guuuuguucg aaacggcaac auuacgaagu ggcuaucugc uaccggauac aaaagcauau     2220

ggagacagaa uagaacgaau guuaagacua ucauuaaaua uagauccuga ugccaaagua     2280

gaagaagaac cagaagaaga accagaagaa acggcagaag auacaacaga agacaccgaa     2340

caagacgagg augaggaaau ggacguagga acugaugaag aagaagaaac agcaaaagaa     2400

agcacugcag aaaaagauga acuauaagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  2467
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt12)

<400>  2467
gggagaaagc uuaccauggc aagagaacua agagcauuac uauuaugggg ccgccgacua       60

agaccucucu uaagagcucc agcacuagca gccguaccag gcggaaagcc cauacuaugu      120

ccaaggagaa caacugcaca acuaggacca agaagaaauc cugcuuggag ucugcaagca      180

gguaggcuuu ucuccacaca aacagcugaa gacaaagaag aacccuuaca uucaauaaua      240

ucuaguacag aaucuguuca aggaaguacc ucaaaacaug aauuucaagc agaaacaaaa      300

aaacuacuag acauaguagc acgaucacua uauagugaaa aagaaguuuu uauaagagaa      360

uuaauaagua acgccucaga ugcacuagaa aaauuacgac acaaauuagu aagcgauggu      420

caagcuuuac cagaaaugga aauacauuua caaacuaacg cugaaaaagg aaccauuaca      480

auacaagaua cagguauagg aaugacacaa gaagaacuug uuaguaaucu aggaacaaua      540

gcucgaucag gaucaaaagc auucuuagac gcauuacaaa accaagcaga agcuagcucg      600

aaaauaauug gucaauuugg aguaggauuu uauucagcau ucaugguugc agacagggua      660

gaaguauauu cacguagcgc ugcaccagga ucauuagguu accaauggcu aucagacggu      720

ucaggcguuu ucgaaaucgc agaagcauca ggaguaagaa caggaacaaa aauaauaaua      780

caccuaaaaa gugauuguaa agaguucucu agugaagcaa gaguuagaga uguaguaaca      840

aaauauucua auuuuguauc guuuccacua uacuuaaaug gacgaagaau gaauacacua      900

caagcaauau ggaugaugga uccaaaagau guacgagaau ggcaacauga agaauucuac      960

agauacguug cacaagcaca ugacaaacca agauauaccu uacauuauaa aaccgacgca     1020

ccuuuaaaua uaagaucaau cuuuuauguu ccagacauga aacccucuau guucgacgua     1080

ucaagagaac uaggaaguag uguggcccuu uauucaagaa aaguccuaau ucaaacaaaa     1140

gcaacagaua uauuaccuaa augguugaga uuuaucagag gaguaguaga uucagaagac     1200

aucccauuaa aucuaaguag ggagcuauua caagaaucag cauuaauaag gaaacuaaga     1260

gacguuuuac aacaaagacu uauaaaauuu uuuauagauc aaagcaaaaa agaugcagaa     1320

aaauacgcua aauuuuucga agacuauggg cuauuuauga gagagggaau aguaacagca     1380

acugaacaag aaguaaaaga agacauugca aaacuacuca gauaugaaag uagugcucug     1440

ccuagcgguc aauuaacaag ucugucugaa uaugcuucac gaaugagggc cggaacaaga     1500

aauauauacu acuuaugcgc accaaaccga cacuuagcag aacauucacc cuauuaugag     1560

gcaaugaaaa agaaagacac agaaguucua uuuugcuuug aacaauucga cgaacucacu     1620

uuacuacacc uaagagaauu ugacaaaaaa aaauuaauua gcgucgaaac agauauagug     1680

guugaccauu auaaagaaga aaaauuugag gauagaucuc cagcggccga augccuuuca     1740

gaaaaagaaa cagaagaacu uauggccugg augagaaacg uucuaggguc uagaguaaca     1800

aaugugaaag uaacauuaag auuagacaca cauccggcaa ugguaacagu ucuagaaaug     1860

ggagcggcaa gacacuuuuu aagaaugcaa caauuggcaa aaacacagga agaaagagca     1920

caauuauuac agccaacacu cgaaaucaac ccuagacacg cauuaauaaa aaaacuaaau     1980

caacuaagag caucagaacc aggacuugca caauugcuag ucgaucaaau auacgaaaau     2040

gcaaugauag cagcaggauu aguagaugau ccacgagcga ugguaggacg acuaaaugag     2100

uuauuaguaa aagcauuaga aagacacuaa ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  2468
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt12)

<400>  2468
gggagaaagc uuaccauggg aaaaauauca ucacuaccaa cacaacuauu caaaugcugc       60

uucugcgacu uccuaaaagu aaaaaugcac acaaugucau caucacaccu auucuaccua      120

gcacuaugcu uauuaacauu cacaucauca gcaacagcag gaccagaaac acuaugcgga      180

gcagaacuag uagacgcacu acaauucgua ugcggagaca gaggauucua cuucaacaaa      240

ccaacaggau acggaucauc aucaagaaga gcaccacaaa caggaauagu agacgaaugc      300

ugcuucagau caugcgaccu aagaagauua gaaauguacu gcgcaccacu aaaaccagca      360

aaaucagcaa gaucaguaag agcacaaaga cacacagaca ugccaaaaac acaaaaagaa      420

guacaccuaa aaaacgcauc acgaggauca gcaggaaaca aaaacuacag aauguaagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  2469
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt12)

<400>  2469
gggagaaagc uuaccauggg aauaccaaug ggaaaaucaa ugcuaguacu acuaacauuu       60

cuagcauucg caucaugcug uauagcagca uacagaccau cagaaacacu augcggagga      120

gaauuaguag auaccuuaca auuuguaugu ggagacagag gauucuauuu cucaagacca      180

gcaucaagag uaucaagaag aucaagagga auaguagaag aaugcuguuu cagaucaugu      240

gacuuagcau uacuagaaac auauugcgca acaccagcaa aaucagaacg agauguauca      300

acaccaccaa caguacuacc agauaacuuu ccaagauacc caguaggaaa auuuuuccaa      360

uacgauacau ggaaacaauc aacacaaaga cuaagaagag gacuaccagc acuacuaaga      420

gcaagaagag gacacguacu agcaaaagaa cuagaagcau uuagagaagc aaaaagacau      480

agaccacuaa uugcauuacc aacacaagau ccagcacacg gaggagcacc accagaaaug      540

gcaucaaaca gaaaauaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  2470
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt12)

<400>  2470
gggagaaagc uuaccaugaa cucauucuca acaucagcau ucggaccagu agcauucuca       60

cuaggacuac uacuaguacu accagccgca uucccagcac caguaccacc aggagaagac      120

ucaaaagacg uugcagcacc acacagacaa ccccuaacau ccucagaaag aauagacaaa      180

caaauaagau acauacuaga cggaauauca gcacuaagaa aagaaacaug caacaaauca      240

aacaugugcg aaucaucaaa agaagcacua gccgaaaaca accuaaaccu accaaaaaug      300

gcagaaaaag acggaugcuu ccaaucaggu uucaacgaag aaacaugccu aguaaaaaua      360

auaacaggac uccuagaauu cgaaguauac cuagaauacc uacaaaacag auucgaauca      420

ucagaagaac aagcaagagc aguacaaaug ucaacuaaag uacuaauaca auuccuacaa      480

aaaaaagcaa aaaaccuaga cgcaauaaca acaccagacc caacaaccaa cgcaucacua      540

cucacaaaac uacaagcaca aaaccaaugg cuacaagaca ugacaacaca ccuuauacua      600

cgaucauuca aagaauuccu ccaaucaucc cuccgagccc ucagacaaau guaaggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  2471
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt12)

<400>  2471
gggagaaagc uuaccaugcc auuacuaugg uuaagaggau uuuuauuagc uaguugcugg       60

auaauaguca gaucaagccc aacgccagga agcgaaggac acucagcagc uccagacugu      120

ccaaguugug cauuagcagc auuaccuaaa gauguuccua auucacaacc agaaauggua      180

gaagcaguaa aaaaacauau auuaaauaug uuacacuuaa aaaaaaggcc agacguaaca      240

caaccaguuc caaaagcagc auuauugaac gcaauaagaa aauuacacgu aggaaaggua      300

ggggaaaacg gauauguaga aauagaagac gauauaggaa gaagagcaga aaugaaugaa      360

cuaauggaac aaacaaguga aauaauaacu uucgcagaaa gcggaacagc aagaaaaaca      420

cuacacuuug aaauaaguaa agaagggagc gauuuaucag uaguagaaag agcagaagua      480

ugguuauuuc uaaaaguacc aaaagcaaau agaacuagaa caaaaguaac aauaagacua      540

uuccaacaac aaaaacaucc acaaggaucu uuagauacug gagaagaagc ggaagaagua      600

ggacuuaaag gagaaagauc agaacuacua uuaagugaaa aaguaguaga ugcacgaaaa      660

aguacauggc auguauuucc aguauccagu ucaauacaaa gacuauuaga ucaaggaaaa      720

agcagcuuag acguuagaau agcuugugaa cagugucaag aaucaggagc aaguuuaguu      780

uuacuaggaa aaaaaaaaaa aaaagaagaa gagggagaag guaaaaaaaa agguggggga      840

gaaggaggag caggagcuga ugaagaaaaa gaacaaucac auagacccuu cuuaaugcua      900

caagcaagac aaucagaaga ucauccacau agaagaagac gaagaggcuu agaaugugau      960

ggaaaaguaa auauauguug caaaaaacaa uucuuuguau cauuuaaaga uauaggaugg     1020

aaugauugga uaauugcacc cagcgguuau caugcaaacu auugugaagg agaaugccca     1080

ucacacauag cgggaacuag uggaaguuca uuaagcuuuc acucaacugu gauaaaucau     1140

uaucguauga gaggccauuc gccguuugca aauuuaaaau cauguugugu accaacaaaa     1200

cuaagaccaa ugaguauguu auauuaugac gauggacaaa auauaauaaa gaaagacaua     1260

caaaauauga uaguagaaga auguggaugu aguuaaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  2472
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt12)

<400>  2472
gggagaaagc uuaccaugga cggauuaccu ggcagagcuu ugggagcagc augucuauua       60

cuauuagcug caggaugguu aggaccagaa gcauggggau cgccaacacc accaccaaca      120

ccagcugcac caccaccacc accaccuccu gguucaccag gcgggucuca agacaccugu      180

acaagcugug gaggcuuuag gaggccagaa gaacuaggaa gaguagaugg agacuuuuua      240

gaagcuguaa aaagacauau acuuaguaga cuccaaauga gaggaagacc aaauauaaca      300

caugccguac caaaagcugc aaugguaacu gcacuucgaa aacuacaugc aggaaaagua      360

agagaagaug gaaggguaga aauaccucau cuagauggac augcaucacc aggagcagau      420

ggacaagaaa gaguaucaga aauaauaucu uuugcagaaa cagauggauu agcgucauca      480

agaguaagau uauacuuuuu cauaucaaac gaaggaaauc aaaauuuauu uguaguacaa      540

gcgagcuuau gguuauaucu aaaauuauua cccuauguuu uagaaaaagg aucaagacga      600

aaaguaagag uaaaaguuua uuuucaggaa caaggacacg gagacagaug gaauauggua      660

gaaaagagag uagacuuaaa aagaagugga uggcauacau ucccacuaac ugaagcaauu      720

caagcacuau uugaaagagg agaaagaaga uuaaaccuag augugcaaug ugauucuugu      780

caagaauuag cagucguacc aguauuuguu gauccaggag aagaaaguca uagaccauuu      840

gugguaguuc aagcaagauu aggagauagu agacauagga uaagaaaaag aggauuagaa      900

ugugauggaa ggacaaauuu auguuguaga caacaauucu uuauugacuu uagauuaaua      960

ggauggaaug auuggauaau agcacccaca ggauauuaug ggaauuauug ugaaggaagu     1020

uguccagcau acuuagcagg aguacccgga ucagcaaguu ccuuucauac agcaguuguc     1080

aaccaauauc gaaugagagg guuaaaucca gguacaguaa acucauguug uauaccaacc     1140

aaacuaagua cuaugagcau guuauauuuu gaugaugaau auaacauugu aaaacgagau     1200

guaccaaaca ugauaguaga agaaugugga ugugcauaag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  2473
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt12)

<400>  2473
gggagaaagc uuaccauggc auuaagagua uuacugcuga cagcuuugac ucuaugucac       60

ggcuucaacc uagacacaga aaaugcuaug accuuucaag aaaaugcacg agguuucgga      120

cagucugucg uccaacuaca aggaucaagg guuguagucg gcgcacccca agaaauugua      180

gcagcaaauc aaagaggcuc cuuauaucaa ugcgacuacu caacagguag cugcgaacca      240

auacgucuuc aaguucccgu ugaagcagug aacaugucac uugguuuaag uuuagcagcu      300

acaacaagcc caccucaacu auuagcuugc ggccccacag uacaccaaac cuguagcgaa      360

aauacuuaug uuaaaggauu guguuuccua uucgguucca auuuacgaca gcaaccucaa      420

aaauucccug aagcacuucg uggaugcccc caagaagaua gcgauauagc auuuuuaauc      480

gacgguuccg gauccauaau accccaugac uuccggagaa ugaaagaauu uguaaguaca      540

gugauggaac aauugaagaa aucuaaaacu cuauuuucuc ugaugcaaua uagugaagaa      600

uuuaggauac acuuuacuuu uaaagaauuu caaaacaacc caaauccgag aucguuagua      660

aaaccgauua cucagcuuuu aggacgaacu cauacagcua cuggaauacg uaaaguagua      720

agagaacucu ucaacauaac aaauggcgca cguaaaaaug cuuuuaagau auuaguagua      780

auuacagacg gagaaaaauu cggagauccu cuaggauacg aagacguaau accagaagcu      840

gauagagagg gcguaauaag auauguaaua ggcguuggag augcauucag aagcgagaaa      900

agcagacaag aauugaacac aaucgcaucu aaacccccac gagaucaugu auuccagguc      960

aauaauuucg aagcucuaaa aacaauacaa aaccaacuga gagagaaaau auuugcaaua     1020

gaagggacac aaacaggcuc aucgagcuca uuugaacaug aaaugagcca agaaggauuu     1080

ucagcagcaa uaaccucaaa cggaccacua uuauccacug uuggaaguua ugauugggca     1140

gggggagucu ucuuauacac guccaaagaa aaaucuacau uuauaaacau gaccagaguu     1200

gacagugaca ugaaugacgc uuaccucggc uaugcagcag cuauuauacu acgaaauaga     1260

guacaaucac uuguuuuagg ggcaccacgg uaccaacaua uuggucuagu ugccauguuc     1320

cgacaaaaua caggaaugug ggaaucaaau gccaauguaa aaggaacaca aauaggagcu     1380

uauuucggcg caucauuaug uuccguagau guagacucaa acggaucaac agauuuaguc     1440

cugauuggug ccccacauua uuaugaacaa acaagaggug gucagguaag uguuuguccg     1500

cucccacgag guagagcccg auggcaaugc gaugcuguac uuuauggaga acaaggacag     1560

ccauggggaa gauucggggc agcacuaaca guacuaggug acgugaaugg ggauaaacua     1620

accgauguag caauaggugc accaggcgaa gaagacaaua gaggagcagu auacuuauuu     1680

cacggaacau caggcucagg aauaagcccu ucgcacucac aaagaaucgc uggcaguaaa     1740

uuaagcccuc gccuucaaua cuuuggacag ucgcuuagug gaggccaaga ucuaacaaug     1800

gacggauuag uugaccuaac gguaggagca cagggucaug uccuacuauu acgaucccaa     1860

ccuguuuugc gugucaaagc aauuauggag uucaauccaa gagaaguagc acgaaauguu     1920

uuugaaugca augaucaagu aguuaaaggc aaagaagcug gagaaguacg gguuugucua     1980

cauguacaaa aauccacacg agaccgucua cgcgaagguc aaauacaauc aguaguuacc     2040

uaugaucuug cacuugacuc uggaagaccu cacucuaggg cuguauuuaa ugaaacuaaa     2100

aauuccacga gacgacaaac acaaguacua ggucuuaccc aaacuuguga aaccuuaaag     2160

cuacaacucc caaauugcau agaagaucca guaaguccaa uaguacugag acucaauuuc     2220

ucccuugucg gaaccccucu aagcgcguuc ggaaacuuac gaccaguacu agcagaagac     2280

gcacagagac uuuuuacugc acuuuuucca uucgagaaaa auugcggaaa cgacaauaua     2340

ugucaagacg acuuaucuau aacauuuuca uucaugucau uagauuguuu gguaguugga     2400

gguccccggg aguucaaugu cacaguaaca gucagaaaug auggagaaga uucuuaccga     2460

acacaaguua ccuuuuucuu uccacuugau uuaagcuacc gaaaagucuc uacacuacag     2520

aaccaacgaa gucaacgcuc guggagacuu gcaugugaaa gcgcuucuuc aacugaaguu     2580

ucaggugcuu ugaaaucaac aucauguagu auaaaccauc ccauuuuucc ggaaaauucu     2640

gaaguuacau uuaacauuac guucgauguc gauucaaagg cuucucuugg uaauaaauua     2700

cuauugaaag caaaugucac auccgaaaau aauaugccaa ggaccaacaa aacagaguuc     2760

caacuugaau uaccuguaaa auaugcuguc uacaugguug uaacaucaca uggaguaucu     2820

accaaauauc ucaauuuuac agcaucugaa aauacuucac gaguaaugca acaccaauac     2880

caaguaucaa auuuaggaca acgaucacuc ccaauuaguc uuguuuuucu agucccaguc     2940

agauugaauc aaacaguaau cugggauaga ccacaaguaa cauuuucuga aaacuuaagc     3000

aguacauguc auacaaaaga acgcuuacca ucccauuccg acuuucuugc ugaauuaaga     3060

aaagcaccug ucgucaauug cucaaucgca gugugccaac gaauacaaug ugacauuccc     3120

uucuuuggca uacaagaaga guuuaacgcu acacuaaagg gcaauuuauc cuuugacugg     3180

uacauaaaaa caucacauaa ucaucuauua auuguaucaa cagcagaaau auuauuuaac     3240

gacagcguau ucacacuucu ccccgggcaa ggagcuuuug ucagaaguca aacagaaaca     3300

aaaguagaac cauucgaagu uccaaacccc uuaccucuca uaguagguuc cucgguaggu     3360

ggauuacuac ugcuugcauu aauuacagcc gcuuuauaua aacuuggauu cuuuaagaga     3420

caauauaagg auaugauguc ugaaggagga ccuccuggcg cagaaccaca auaaggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  2474
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt12)

<400>  2474
gggagaaagc uuaccauguu cucacuuaaa acucucccau ucuuacuacu acuacacguc       60

caaauaucaa aagccuuccc cguauccuca aaagaaaaaa auacuaaaac aguucaagac      120

uaccucgaaa aauucuacca acuaccuuca aaccaauacc aaucaacaag aaaaaauggu      180

acuaauguca uagucgaaaa auuaaaagaa augcaaagau uuuuuggacu uaacguuaca      240

ggaaaaccua acgaagaaac ccuagacaug augaaaaaac cacgaugcgg agucccagac      300

ucaggaggcu ucaugcuaac accaggaaau ccaaaauggg aacguacaaa cuuaacauac      360

cgcauacgaa acuacacccc acaacuaagu gaagcagaag uagaacgcgc cauaaaagac      420

gccuucgaac uauggucagu agcaagccca cucauauuua cuagaauauc acaaggugaa      480

gcugauauca auaucgcauu uuaccaacga gaccacggcg auaacucacc auucgacggc      540

ccaaauggaa uacuagccca cgcauuccaa ccaggacaag gaauaggagg ugacgcacac      600

uucgacgcag aagaaaccug gacaaacaca ucagcaaacu auaacuuauu ucuagucgcc      660

gcacacgaau ucggacacuc acuagguuua gcacacucau cagacccagg cgcacuaaug      720

uaucccaacu augcauucag agaaaccuca aauuauucau uaccucaaga cgauauagac      780

ggaauucaag caauauaugg acuuucuuca aauccaauac aaccaacagg cccuucaacc      840

ccaaaacccu gugaucccuc acuaacauuc gacgcaauca caacucuacg aggagaaauu      900

uuauucuuua aagacagaua uuuuuggaga agacacccac aacuacaaag aguagaaaug      960

aacuucauaa gcuuauucug gccaucacua ccaacaggca uucaagcagc auacgaagac     1020

uucgauagag accuaauauu cuuauuuaaa ggaaaccaau auugggcacu aucagguuac     1080

gacauacuac aaggauaccc aaaagacaua uccaauuaug gauucccauc aucaguacaa     1140

gcaauagacg cagcaguauu cuauagauca aaaaccuacu ucuucguaaa ugaucaauuc     1200

uggagauacg acaaccaacg ccaauucaug gaacccggau aucccaaauc aauaucagga     1260

gcauucccag gaauagaauc aaaaguagac gcuguauucc aacaagaaca uuucuuucau     1320

gucuucuccg gacccaggua cuacgcauuu gauuuaauag cccaaagagu aacacgagua     1380

gcaagaggaa auaaaugguu gaauuguaga uacggauaag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2475
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt12)

<400>  2475
gggagaaagc uuaccaugag ccuuuggcaa cccuuaguuu uaguuuuacu aguauuagga       60

ugcugcuucg cagcuccuag acaaaggcaa ucaacacuug uucucuuucc aggagacuua      120

cgaacaaauc uaacagauag acaacuagca gaagaauacu uauauagaua uggauauacc      180

agaguugcag aaaugagagg agaaaguaaa ucguuaggac cugcccuacu acuucuucaa      240

aaacaauuau cauuaccaga aacaggagaa cuagauucug cuacacuaaa agcaaugaga      300

accccuagau gcggaguucc agauuuaggc cgauuucaaa cauuugaagg agaccuaaaa      360

uggcaccauc auaauauaac uuauuggaua caaaauuacu cugaagacuu accgagagcc      420

guaauagacg augcauucgc uagagcauuu gcuuuauggu cagcaguuac accccuaaca      480

uuuacuagag uauauucaag agaugcugau auaguaauuc aauuuggagu cgcagaacau      540

ggugauggau auccauuuga uggaaaagac ggauuauuag cccacgcauu cccaccuggu      600

ccaggcauuc aaggagaugc acauuucgac gaugacgaau uauggagcuu aggaaaagga      660

guaguaguac cuacacgcuu ugggaaugcu gauggagcag caugccauuu cccauuuauu      720

uucgaaggua gaucauacuc ugcaugcacu acagauggaa gauccgaugg auuaccuugg      780

ugcagcacaa cagcuaauua ugacacugau gacagauuug guuuuugucc auccgaaaga      840

cuuuacacac aagacggaaa ugcagauggu aaaccaugcc aauuuccuuu uauauuucag      900

ggacaaucau auucagcuug uacaacagau gggagaagug auggauaccg cuggugugca      960

accacugcca auuaugauag agacaagcua uuuggauucu guccuacaag agcagacucg     1020

acuguaaugg guggaaauuc agccggagaa cuaugugucu ucccauuuac auuuuuaggu     1080

aaagaauacu cuacauguac uucagaaggc cguggugaug gaagacuuug gugugcaaca     1140

acaucaaauu ucgacucuga caaaaaaugg ggauuuuguc cagaucaagg auacagcuua     1200

uuucuaguug cagcacacga auuuggacau gcacuagguu uagaucacag uucaguacca     1260

gaagcauuaa uguauccaau guauagauuu accgaagggc cuccccuuca caaagaugac     1320

guuaauggaa uaagacacuu auacggaccc agaccugaac cugaaccaag accuccuacu     1380

acaacuacuc cacaaccaac agccccacca acaguaugcc caacgggacc gccaacagua     1440

cacccaagcg aaagaccaac ugcuggacca acaggaccac ccagugcagg uccaacuggu     1500

ccaccuacag caggcccauc uacugcaaca acagucccau uaaguccagu ggacgaugca     1560

ugcaacguua acauauucga cgcaauugca gaaauuggaa aucaauuaua ucuuuuuaaa     1620

gauggaaaau acuggagguu cucagaagga agagguucaa gaccacaagg uccauuucuu     1680

auagcugaua aauggccagc ucuccccaga aaauuagacu caguauucga agaacgauua     1740

aguaaaaaau uauucuucuu uucaggcaga caaguuuggg uauauacugg ugcaagugua     1800

cucggaccaa gaagacuuga uaaauuaggc uuaggggcag acguugcaca aguaacugga     1860

gcccuaagau ccggucgagg aaaaauguua uuauucucag gaagaagauu auggagauuu     1920

gauguuaaag cacaaauggu ugauccaaga ucagcaucag aaguagacag aauguuucca     1980

ggcguaccac uagauacuca ugacguauuu caauaucggg aaaaagcgua cuuuugucaa     2040

gauagauuuu auuggagagu uucuucaaga ucagaauuaa accaaguaga ucaaguugga     2100

uauguaacau augauauccu acaaugccca gaagacuaag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  2476
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt12)

<400>  2476
gggagaaagc uuaccaugca cccaggagua cuagcagcau ucuuauucuu aucuuggacc       60

cacuguagag cacuaccucu accuagcgga ggagaugaag augaccucuc agaagaagac      120

cuacaauucg cagaaagaua ucuacgaucu uauuaccacc caacaaacuu agcaggaaua      180

cuaaaagaaa acgcugcauc aucaaugaca gaaagacuaa gagaaaugca aucauuuuuc      240

ggacuagaag uaacaggaaa auuagacgac aacacauuag acguaaugaa aaaaccaaga      300

ugcggaguac cagaugucgg agaauacaac gucuucccaa gaacauuaaa auggagcaaa      360

augaaccuaa cauauagaau aguaaauuac acacccgaca ugacacacuc agaaguagaa      420

aaagcauuua aaaaagcauu caaaguaugg uccgauguca caccccuaaa cuucacaaga      480

uuacaugacg gaauagcaga cauaaugaua ucuuucggaa uaaaagaaca cggugacuuc      540

uacccuuucg acggaccauc aggacuauua gcacacgcau ucccacccgg accaaauuac      600

ggaggagaug cacacuuuga cgaugaugaa acuuggacau caucaucaaa agguuauaac      660

uuauuucucg uagcugccca cgaauucgga cacucacuag ggcuagacca cagcaaagac      720

cccggagcau uaauguuucc aauuuauaca uauacaggaa aaagucacuu uaugcuaccg      780

gacgacgacg uacaaggcau acaaucacuc uacgguccag gagacgaaga cccaaaccca      840

aaacacccca aaacaccaga uaaaugcgac ccaucacuau cauuagaugc aauaacauca      900

uuaagaggag aaacuaugau uuucaaagac agauucuucu ggagguuaca cccccaacaa      960

guagaugcag aacucuuucu aacaaaauca uuuuggccag aauuaccaaa uagaauugac     1020

gcugcauacg aacacccauc acacgaccua auauuuauau ucagaggaag aaaauucugg     1080

gccuuaaacg gauaugacau acuagaagga uacccaaaaa aaauaucaga auuaggucua     1140

cccaaagaag uaaaaaaaau aucagcagcc guccacuucg aagacacugg aaaaacauua     1200

cucuuuagug gcaaccaagu auggagauau gacgauacaa accacauaau ggauaaagac     1260

uacccaagau uaauagaaga agacuuucca ggaauuggag acaaaguaga cgccguauac     1320

gaaaaaaaug gauacauaua cuuuuucaac ggaccaauuc aauucgaaua uuccauaugg     1380

ucaaaccgaa uaguuagggu aaugccagca aacuccauau uaugguguua aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2477
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt12)

<400>  2477
gggagaaagc uuaccaugga aacaccaaau acaacagaag acuaugacac aacuacagaa       60

uucgacuaug gcgacgccac accaugccaa aaaguaaacg aaagagcauu cggcgcacaa      120

uuauuaccac cuuuauacuc auuaguauuc guaauaggau uaguaggaaa cauacuagua      180

guauuaguac uaguacaaua caaaagacua aaaaacauga cauccauaua ccuacuaaac      240

uuagcaauau cugaccuacu auuccuauuc acucuaccau ucuggaucga cuauaaacua      300

aaagaugacu ggguuuucgg ugacgcaaug ugcaaaaucc ucucaggauu uuacuacaca      360

ggauuauaca gcgaaaucuu uuucaucaua cuauuaacca ucgaccgaua ccuagccaua      420

guacacgcag uauucgcacu cagagccaga acaguaacuu ucggcguaau aacaucaaua      480

auaaucuggg cauuagccau acucgcauca augccaggac uauacuucuc aaaaacacaa      540

ugggaauuca cccaucacac augcucauua cacuucccuc acgaauccuu aagagaaugg      600

aaacuauuuc aagcccuaaa auuaaacuua uucggacuag uacuaccuuu acuaguaaug      660

auaaucuguu acacaggaau uauaaaaaua cuacucagaa gacccaacga aaaaaaauca      720

aaagccguaa gauuaauauu cguaauaaug auaauuuucu ucuuauucug gacaccauac      780

aacuuaacaa uacucauuuc cgucuuccaa gacuucuuau ucacucacga augcgaacaa      840

ucaagacauc uagaccuagc aguccaaguc accgaaguaa uagcauacac acacugcugc      900

guaaacccag uaauuuacgc auucguagga gaacgauuca gaaaauaccu uagacaacuu      960

uuucacagaa gaguagcagu ccaccuuguc aaauggcuac cauuuuuauc uguagacaga     1020

cuagaaagag uaucuucaac aucaccaucu acaggagaac acgaacucuc ugccggcuuu     1080

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  2478
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt12)

<400>  2478
gggagaaagc uuaccaugcg aacacuagcc ugccuauuac uacuaggaug cggauaccua       60

gcacacguac uagcagaaga agcagaaaua ccaagagaag uaauagaaag acuagcaaga      120

ucacaaauac acaguauaag agaccuacaa agacuacuag aaauagacuc aguaggauca      180

gaagacucac uagacacauc acuaagagca cacggcguac augcaacaaa acacguaccc      240

gaaaaaagac cauuaccaau aagaagaaaa agaagcauag aagaagccgu accagcagua      300

uguaaaacaa gaacaguaau auacgaaaua ccaagaagcc aaguagaccc aacaucagcc      360

aacuucuuaa uauggccacc augcguagaa guaaaaagau gcacaggaug cugcaacaca      420

agcagcguca aaugccaacc aaguagagua caccaucgau caguaaaagu agcaaaagua      480

gaauacguca gaaaaaaacc aaaacuaaaa gaaguacaag uaagacucga agaacaccua      540

gaaugcgcau gcgccacaac aagccuaaac ccagacuaca gagaagaaga cacaggaaga      600

ccaagagaau caggaaaaaa acgaaaaaga aaaagacuaa aaccaacuua aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  2479
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt12)

<400>  2479
gggagaaagc uuaccaugaa cagaugcugg gcacuauucc uaucauuaug cuguuacuua       60

agacuaguau cagcagaagg agauccaaua ccagaagaau uauacgaaau guuaagugau      120

cacucaauaa gaagcuuuga cgauuuacaa agacuacuac auggagaucc aggagaagaa      180

gacggagcag aacuugaucu aaauaugaca agaucacaca guggaggaga auuagaauca      240

cuagccagag gaagaagaag ucuaggauca cucacaaucg cagaaccagc aaugauagca      300

gaauguaaaa caagaacaga agucuucgaa aucucaagac gacuaauaga cagaacaaau      360

gcaaacuucu uaguauggcc accaugcgua gaaguacaaa gaugcucagg augcugcaau      420

aacaggaacg uacaauguag accaacacaa guacaacuaa gacccgugca aguaagaaaa      480

auagaaauag uaagaaaaaa accaaucuuu aaaaaagcaa caguaacacu agaagaucau      540

cuagcaugca aaugcgaaac aguagcagcu gcaagaccag uaacaagauc accaggagga      600

agccaagaac aaagagcaaa aacgccacaa acaagaguaa caauaagaac aguuagagua      660

agaagaccac caaaaggaaa acauagaaaa uucaaacaca cacacgauaa aacagcauua      720

aaagaaacau uaggagcaua aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  2480
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt12)

<400>  2480
gggagaaagc uuaccauguc auuauucgga uuauuacuuu uaacaucugc auuagcagga       60

caaagacaag gaacacaagc agaaucaaac cuaucaagca aauuucaauu uucaucaaau      120

aaagaacaaa auggcguaca agauccacaa cacgaaagaa uaauaacagu aagcacuaac      180

ggaucaauac acagcccccg auucccacau acauacccaa gaaacacagu auuaguaugg      240

agauuagucg ccguagaaga aaauguaugg auacaacuua cauucgauga aagauucgga      300

uuagaagacc ccgaagacga cauaugcaaa uacgacuucg uagaaguaga agaacccuca      360

gacggaacaa uauuaggucg uuggugcgga ucaggaacag uaccaggaaa acaaauaagu      420

aaaggaaacc aaauaagaau ucgauucgua ucagaugaau acuuuccauc agaaccagga      480

uucugcaucc auuacaauau aguaaugcca caauuuacag aagcaguauc accaagcgua      540

uuaccaccau cagcccuacc ucuagacuua uuaaauaacg caauaacagc auuuagcacc      600

uuagaagacu uaauacgaua cuuagaacca gaacgauggc aacuagaccu ugaagaccua      660

uacagaccaa cauggcaauu acuaggaaaa gcauucgucu uuggcagaaa aucaagagua      720

guagaucuaa accuacuaac agaagaagua agauuauaca guugcacacc uagaaacuuc      780

ucaguaagca uaagagaaga acuaaaaaga acagacacca uauucuggcc aggaugccua      840

cuaguuaaaa gaugcggagg aaauugcgca uguugcuuac acaacuguaa cgaaugccaa      900

ugcguacccu caaaaguaac aaaaaaauac cacgaaguac uacaauuaag accaaaaaca      960

ggaguaagag gacuccacaa aucacuuaca gacguagcac uagaacacca cgaagaaugu     1020

gacugcguau gcagaggcuc aaccggagga uaaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  2481
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt12)

<400>  2481
gggagaaagc uuaccaugca uagauuaaua uucguauaca cacuaauaug ugcaaacuuc       60

ugcucaugca gagacaccag ugcaacaccc caaagcgcau caauaaaagc acuacgaaac      120

gcaaacuuaa gaagagacga ucuauauaga agagaugaaa caauacaagu aaaaggaaac      180

ggauacguac aaucaccacg auuuccaaau ucauacccac gaaaccuauu auuaacaugg      240

cgacuacacu cacaagaaaa uacaagaaua caacuugucu ucgacaacca auucggacua      300

gaagaagcag aaaaugacau augcagauau gacuucguag aaguagaaga cauaucagaa      360

acuucaacaa uaauaagagg aagauggugu ggacacaaag aagucccacc aagaauaaaa      420

ucaagaacaa accaaauaaa aauaaccuuc aaaucagaug acuacuucgu agcaaaaccg      480

ggcuuuaaaa uauacuauag ccuauuagaa gacuuccaac cagcagcagc aucagaaacc      540

aacugggaau caguaacaag cucaauaucu ggaguaucau acaacucacc aucaguaaca      600

gauccaacac uaauagcaga cgcauuagac aaaaaaauag ccgaauucga cacaguagaa      660

gaucuacuaa aauacuucaa cccagaauca uggcaagaag accuagaaaa cauguaccua      720

gacacaccaa gauacagagg aagaucauac caugacagaa aaaguaaagu agaccuagac      780

agacuaaacg acgaugcaaa aagauacagc ugcacaccaa gaaauuacuc aguaaacaua      840

agagaagaac uaaaacuagc aaacguagua uucuucccaa gaugcuuauu aguacaaagg      900

ugcggaggaa auuguggaug cggaacagua aacuggagau ccuguacaug caacucaggc      960

aaaacaguca aaaaauacca cgaaguacua caauucgaac caggacacau aaaaagaaga     1020

ggcagagcaa aaacaauggc acuaguagac auacaacucg aucaccacga aagaugcgac     1080

uguauaugcu caagcagacc accacgauaa ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  2482
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt12)

<400>  2482
gggagaaagc uuaccauggu aacacacuca aaauucccag cagcaggaau gucacgaccu       60

cuagacacau cauuacgacu aaaaacauuc ucaucaaaau cugaauacca acuaguagua      120

aacgcaguaa gaaaauuaca agaaucagga uucuacuggu cagcaguaac aggaggagaa      180

gcaaaccuac uauuaucagc agaaccagca ggaacauucc uaauaagaga cucaucagac      240

caaagacacu ucuuuacacu aucaguaaaa acccaaucug gaacaaaaaa ccuacgaaua      300

caaugugaag gaggauccuu cucucuacaa ucagacccaa gaucaacaca accaguaccc      360

agauuugacu gcguacuaaa auuaguacac cacuacaugc ccccacccgg agcaccauca      420

uucccaucac ccccaacaga acccucauca gaaguaccag aacaaccauc agcacaacca      480

cuaccaggcu caccaccaag aagagcuuau uacauauacu ccggaggaga aaaaauacca      540

cuaguucuau caagacccuu aucaucaaac guagccacac uacaacaccu augcagaaaa      600

acaguaaacg gacacuuaga cucauacgaa aaaguaacac aacuuccagg accaauaaga      660

gaauucuuag aucaauacga cgcaccauua uaaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  2483
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt12)

<400>  2483
gggagaaagc uuaccauggu accaucagca ggacaauuag cauuauucgc auuaggaaua       60

guauuagcag caugucaagc auuagaaaau ucaacaucac cauuaucagc agacccacca      120

guagcagcag caguaguauc acauuuuaau gauugcccag auucacauac acaauucugc      180

uuucauggaa cauguagauu uuuaguacaa gaagauaaac cagcaugugu augucauuca      240

ggauauguag gagcaagaug ugaacaugca gauuuauuag ccguaguagc agcaucacaa      300

aaaaaacaag caauaacagc auuaguagua guaaguauag uagcauuagc agucuuaaua      360

auaacaugug uauuaauaca uuguugucaa guaagaaaac auugugaaug gugcagagca      420

uuaauaugua gacaugaaaa accaucagca cuauuaaaag gaagaacagc auguugucac      480

ucagaaacag uaguauaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  2484
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt12)

<400>  2484
gggagaaagc uuaccaugcc accaagugga uuaagacuac uaccauuacu auuaccacua       60

uuauggcuac uaguauuaac accuggaaga ccagcugcag gccuaucaac cugcaaaaca      120

auagacaugg aacuaguaaa acgaaaaaga auagaagcaa uaagaggcca aauacuauca      180

aaacuaagau uagcaucacc accuucccaa ggagaaguac caccaggccc acuaccagaa      240

gcaguacuag cacuauacaa cuccacaaga gacagaguag caggcgaauc agccgaacca      300

gaaccagaac cagaagcuga cuacuacgca aaagaaguaa cuagaguauu aaugguagaa      360

acacacaacg aaaucuauga caaauuuaaa caaucuacac auucuauaua uauguucuuc      420

aauacaagcg aauuacgaga agcaguaccc gaaccaguac uauuaucaag agcugaacuc      480

cgauuacuaa gauuaaaacu aaaaguagaa caacacguag aacuauacca aaaauauucu      540

aauaauucau ggagauaucu uagcaauaga uuacuagcac cauccgacuc accugaaugg      600

cuaucauuug auguaacagg aguaguacgu caauggcuau cacgaggcgg agaaauagaa      660

ggauuuagau uaagcgcuca cugcagcugu gacucaagag acaacacauu acaaguagac      720

aucaacggau ucacaacagg aagaagagga gaucuagcca caauacacgg aaugaacaga      780

ccauuucuac uauuaauggc aacaccacua gaaagagcac aacaucuaca aucuucaaga      840

cacagaagag cauuagacac aaacuacugc uuuucaagca cagaaaaaaa uugcugcguc      900

agacaauuau auauagauuu cagaaaagau uuaggcugga aauggauaca ugaaccaaaa      960

ggauaccacg caaacuucug ccuaggacca ugcccauaca uuuggucauu agauacccaa     1020

uacucaaaag uucuugcauu auacaaccaa cacaacccug gagcaagugc agcaccaugu     1080

ugcguacccc aagcauuaga accacuacca auaguauauu acguuggccg aaaacccaaa     1140

guagaacaac uaucaaacau gauagucaga ucauguaaau guucauaagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  2485
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt12)

<400>  2485
gggagaaagc uuaccaugca cuacugcgua cucucagccu uccuaauacu acaccuagua       60

acaguagcau uaagcuuauc aacaugcuca acacuagaca uggaucaauu caugagaaaa      120

agaauagaag caauaagagg ccaaauacua ucaaaacuua aauuaacauc accaccagaa      180

gacuaucccg aaccagaaga aguaccacca gaaguaauau caauauauaa cucaacaaga      240

gaccuauuac aagaaaaagc aagccgaaga gcagcagcau gcgaacgaga aaggucagac      300

gaagaauacu acgccaaaga aguauacaaa auagacaugc cacccuucuu cccaucagaa      360

aaugccauac cccccacauu uuacagacca uacuucagaa ucguaagauu cgacguauca      420

gcaauggaaa aaaacgcauc aaaucuaguu aaagcagaau ucagaguauu cagacuacaa      480

aacccaaaag caagaguacc agaacaaaga auagaacuau accaaauacu uaaauccaaa      540

gaucuaacau caccuacaca aagauauaua gacucaaaag uaguaaaaac uagagcagaa      600

ggcgaauggc uauccuucga cguaacagac gccguucacg aauggcuuca ccacaaagac      660

cgaaacuuag gauucaaaau aucacuucac uguccauguu gcacauuugu ccccucaaau      720

aacuacauaa uccccaauaa aucagaagaa cucgaagcaa gauucgccgg aauagacgga      780

acuagcacau auaccuccgg agaccaaaaa accauaaaau cuacaagaaa aaaaaacucu      840

ggaaaaacac cacacuuacu auuaaugcua cuacccucau accgacucga aucucaacaa      900

acaaacagac gaaaaaaaag agcauuagac gccgcuuauu guuucagaaa uguacaagau      960

aacugcugcc uacgaccacu auacauagau uucaaaagag aucuaggcug gaaauggauc     1020

caugaaccaa aaggcuauaa cgcaaacuuc ugcgcuggag caugcccaua ccuaugguca     1080

ucagacacac aacauucaag aguauuauca cuuuacaaca ccauaaaucc cgaagcauca     1140

gcaagccccu guugcguauc acaagaccua gaaccacuaa ccauccuaua cuauauagga     1200

aaaacuccaa aaauagaaca acuaucuaau augauaguaa aaucaugcaa augcucuuaa     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  2486
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt12)

<400>  2486
gggagaaagc uuaccaugaa aaugcacuua caaagagccc uaguaguccu agcuuuacuu       60

aacuucgcaa ccguaucccu aagccuauca acuuguacaa cccuagacuu uggacacaua      120

aaaaaaaaac gcguagaagc aauuagagga caaauauuau cuaaacuaag auuaaccuca      180

ccaccagaac caacaguaau gacacaugua ccauaccagg uauuagcacu auacaauuca      240

acacgcgaac uacuagagga aaugcaugga gaaagagaag aaggaugcac acaagaaaac      300

acagaaucag aauacuacgc aaaagaaauc cauaaauucg acaugauaca aggauuagca      360

gaacacaacg aacuagcagu augcccaaaa ggaauaacau caaaaguauu uagauucaau      420

guaucuucag uugaaaaaaa uagaacuaac cucuuuagag ccgaauuccg cguauuaaga      480

guccccaacc caagcagcaa acgaaacgaa caaagaauag aacuauucca aauacuaagg      540

ccagacgaac acauagcaaa acaaagauau auaggaggca aaaauuuacc cacaagaggu      600

acagcagaau ggcuaucauu cgauguaaca gauaccguaa gagaauggcu acuaagaaga      660

gaaaguaauc uaggccuaga aauaucaaua cauuguccau gucacacauu ccaaccaaac      720

ggagacauau uagaaaacau acacgaagua auggaaauaa aauucaaagg aguagacaac      780

gaagaugauc acggacgagg cgaucuaggc agauuaaaaa aacaaaaaga ccaccacaau      840

ccacaccuaa uauuaaugau gauaccacca cacagacuag acaauccagg ccagggaggc      900

caaagaaaaa aaagggcacu agacaccaac uacugcuuca gaaaccuaga agaaaacugc      960

ugcguaagac cacuauacau ugacuucaga caagaccuag gcuggaaaug gguccaugaa     1020

ccaaaaggau acuacgccaa cuuuugcuca ggaccaugcc cauaccucag aucagcagac     1080

acaacccacu caacaguauu agguuuauac aacacauuaa acccagaagc aagugccucc     1140

ccuuguugcg uaccacaaga ccuagaacca uuaaccauau uauauuaugu aggacgaaca     1200

ccaaaaguag aacaacuauc aaauauggua guaaaaucau gcaaauguag cuaaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2487
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt12)

<400>  2487
gggagaaagc uuaccauggc uccuguagcc guaugggcag cucuagccgu aggauuagaa       60

uuaugggcug cugcccaugc acuaccugcc caaguugcuu uuacaccaua cgcaccagaa      120

ccugguucaa cauguagauu aagagaauau uaugaucaaa cugcucaaau guguuguuca      180

aaauguagcc cuggucaaca ugccaaagua uucuguacua aaacuucuga uaccguaugu      240

gauucaugug aggauucaac auauacacaa uuauggaauu ggguaccaga auguuuauca      300

uguggaucuc gauguucauc agaucaagua gaaacacaag cuuguacaag agaacaaaau      360

agaauaugua cuuguagacc agguugguac ugcgccuuau caaaacaaga aggauguaga      420

cuaugcgccc cacuacgaaa auguagacca ggauuuggug uugcacgucc aggaacagaa      480

acaucagacg uaguauguaa accaugcgcu cccgguacau ucucaaauac aacaucaucc      540

accgauauau gucgaccaca ucaaauaugu aauguaguag caauaccagg aaaugcaucu      600

auggacgcag uauguacauc aacaucaccc acaagaucaa uggcaccagg ugcuguccau      660

cuaccacaac cuguuucaac aagaucacaa cauacacaac cuacacccga accauccaca      720

gcaccaagua ccucauuucu uuuaccuaug ggaccaucac caccugcaga aggaucaaca      780

ggagauuuug cacuuccagu aggacuaaua guuggaguaa cugcacuagg auuauuaaua      840

auuggagucg uaaauugugu aauaaugaca caaguaaaaa aaaaaccauu augcuuacaa      900

cgagaagcca aagucccuca uuuaccagca gacaaagcua gaggaaccca aggaccagaa      960

caacaacacc uacucauaac cgcaccuuca ucaucuucau caucuuuaga aucaucugca     1020

ucugcauuag auagaagagc acccacaaga aaucaaccac aagcaccugg aguugaagcu     1080

uccggggcag gugaagcucg agcuucaaca ggaucuucag auucaucucc agguggucau     1140

ggaacccaag uuaauguaac uugcaucgua aauguauguu caucaucaga ucacucauca     1200

caauguucau cacaagcaag uucaacuaug ggagauacug acucaagccc aucggaauca     1260

ccuaaagaug aacaaguacc auuuaguaaa gaagaaugug cauuuagauc ucaacuugaa     1320

acaccagaaa cuuuauuagg aaguacagaa gaaaaaccac uaccauuagg aguacccgau     1380

gcagggauga aaccuuccua aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  2488
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt12)

<400>  2488
gggagaaagc uuaccaugcc aguaaugagg cuauuuccau guuuuuuaca auuacuagca       60

ggauuagcau uaccagcagu accaccacaa caaugggcau uaagugcagg aaauggaagu      120

ucagaaguag aaguaguacc auuucaagaa guauggggaa gaucauauug uagagcacuu      180

gaaagauuag uagauguagu aagugaauau ccaagcgaag uagaacauau guuuucacca      240

ucauguguaa guuuauuaag auguacagga uguuguggag augaaaaucu acauugugua      300

ccaguagaaa cagcaaaugu aacaaugcaa uuacuaaaaa uaagaagugg agauagacca      360

ucauauguag aauuaacauu cagucaacau guaagaugug aauguagacc auuaagagaa      420

aaaaugaaac cagaaagaag aagaccaaaa ggaagaggaa aaagaagaag agaaaaacaa      480

agaccaacag auugccauuu auguggagau gcaguaccaa gaagauaagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  2489
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt12)

<400>  2489
gggagaaagc uuaccaugac agacagacaa acagauacag caccuucacc aagcuaucac       60

uuauuaccug guagaagaag aacaguagau gcagcagcua guaggggaca aggaccagaa      120

ccagcuccag gaggaggugu agaaggagua ggggcaagag gaguagcuuu aaaauuauuu      180

guacaacuuu uaggauguag cagguuugga ggagcgguug uaagagccgg ugaagcagaa      240

ccgucaggag cagcaagauc agcaagcuca ggaagggaag aaccacaacc agaagaaggu      300

gaagaagaag aagaaaagga agaagaaagg ggaccacaau ggcgacuggg agcaagaaag      360

ccagguaguu ggacaggaga agcagcagua ugcgcagacu cugcaccagc agcaagagca      420

ccgcaagcau uagcucgagc aaguggaagg ggaggaagag uagcucgaag aggagcagaa      480

gaaucaggac cuccacacag uccaaguagg agaggaagug caagcagggc aggaccaggg      540

agagcaagcg aaacaaugaa uuuucuauug aguuggguac auuggagccu agcccuauua      600

uuauauuuac aucaugcuaa auggucacaa gcagcaccaa uggcagaagg aggaggacaa      660

aaucaucaug agguagugaa auuuauggau guauaucaaa gaucauauug ucauccaaua      720

gaaacauuag uugacauauu ucaagaauau ccagaugaaa uagaauauau cuuuaaaccu      780

agcugugucc cauugaugag auguggagga uguuguaaug augagggauu agaaugcgua      840

ccaacagaag aaaguaacau aacaaugcaa auaaugcgaa uaaaaccaca ucaaggacaa      900

cauauaggag aaaugucauu uuugcaacau aacaaaugcg aaugcaggcc aaaaaaagac      960

agagcaagac aagaaaaaaa aaguguuaga ggaaaaggaa aaggucaaaa aaggaaaaga     1020

aaaaaaagua gauauaaaag uuggagugua uauguaggag caagauguug uuuaaugcca     1080

uggagucuac cgggaccaca uccaugugga ccuugcagug agaggagaaa acacuuauuu     1140

guucaagacc cacaaacaug uaaauguucu uguaaaaaca cugauagcag auguaaagcu     1200

cgacaauugg aauuaaauga aaggacaugu agaugugaua aaccaagaag auaaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2490
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt12)

<400>  2490
gggagaaagc uuaccaugaa cuuccuauua agcuggguac acuggucacu agcauuauua       60

uuauauuuac aucacgccaa auggucacaa gcagcaccaa uggcagaagg aggaggacaa      120

aaccaccacg aaguaguaaa auuuauggau guauaccaaa gaagcuauug ccauccaaua      180

gaaacacuag uagacauauu ccaagaauau ccagaugaaa uagaauauau auuuaaacca      240

uccugcguac cauuaaugag augcggagga ugcugcaacg acgaaggacu agaaugcgua      300

ccaacagaag aaaguaauau aacaaugcaa auaaugagaa uaaaaccaca ccaaggacaa      360

cacauaggcg aaaugaguuu cuuacaacau aacaaaugcg aaugcagacc aaaaaaagac      420

agagcaagac aagaaaaaaa aagcguaaga ggaaaaggaa aaggacaaaa aagaaaaaga      480

aaaaaaagca gauacaaaag cuggagcgua uacguaggag caagaugcug cuuaaugcca      540

uggucacuac caggaccaca cccaugcgga ccauguucag aaagaagaaa acaucuauuu      600

guacaagacc cacaaacaug uaaaugcuca ugcaaaaaca ccgacaguag auguaaagca      660

agacaacuag aacuaaauga aagaaccugu agaugugaca aaccaagaag auaaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  2491
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt12)

<400>  2491
gggagaaagc uuaccauguc accacuauua agaagacuac uauuagcagc auuacuacaa       60

cuagcaccag cacaagcucc aguaagccaa ccagacgcac ccggacauca aagaaaagua      120

guaucaugga uagauguaua cacaagagca acaugucaac caagagaagu uguaguccca      180

cuaacaguag aauuaauggg aacaguagca aaacaauuag uaccaucaug cguaaccgua      240

caaagaugcg gaggauguug cccagacgau ggcuuagaau gcguaccaac uggacaacau      300

caaguaagaa ugcaaauacu aaugauaaga uacccaucau cacaauuagg agaaauguca      360

uuagaagaac auucacaaug cgaaugcaga ccaaaaaaaa aagacucagc aguaaaacca      420

gacagagcag caacaccaca ucauagacca caaccaagau caguaccagg augggacuca      480

gcaccaggag caccaucucc agcagacaua acacauccaa caccagcacc aggaccauca      540

gcacaugcag cacccucaac aacaagugca cuaacaccag gaccagcagc agcagcagcu      600

gacgcagcag caucaucagu cgcaaaagga ggagccuaag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  2492
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt12)

<400>  2492
gggagaaagc uuaccaugca ccuauuagga uucuuuagcg uagcgugcag uuuauuggca       60

gcagcacuau uaccaggucc acgugaagca ccagccgcag ccgcagcuuu cgaaucagga      120

uuagacuuaa gcgacgcuga acccgacgca ggcgaagcaa cagcauacgc uucaaaagau      180

cuagaagaac aacuaagauc uguaucuuca guagacgaau uaaugacagu acuauaccca      240

gaauauugga aaauguauaa augccaacua agaaaaggag guuggcaaca caauagagaa      300

caagcaaacu uaaacuccag aacagaagag acuauaaaau uugcagcagc acauuacaac      360

acagaaauuc uaaaaucaau agacaaugaa uggagaaaaa cucaauguau gccaagagaa      420

guaugcauag acguagguaa agaauucggu guagccacca acacauuuuu uaaaccacca      480

ugcguaucag uauauagaug cggaggcugu ugcaauucag aaggauuaca auguaugaau      540

accucuacaa gcuaccuauc aaaaacacua uucgaaauaa cuguaccauu aucacaagga      600

ccaaaaccag uaacaauauc auuugcaaac cacacaucau gucgaugcau gucaaaauua      660

gacguauacc gacaaguaca caguauaaua agaagaucac uacccgcaac acuaccacaa      720

ugccaagcag caaauaaaac augcccaacu aacuacaugu ggaauaauca uauuuguaga      780

ugccuagcac aagaagauuu cauguucuca agugaugcag gugacgacuc uacugacgga      840

uuucaugaca uauguggacc aaauaaagaa cuagacgaag aaacauguca augcguaugc      900

agagcaggac uucgaccagc auccuguggu ccacauaaag aacuagauag aaauucaugc      960

caauguguuu guaaaaauaa auuauucccc agccaaugcg gagcaaauag agaauuugau     1020

gaaaauacau gccaaugugu auguaaaaga accugcccaa gaaaucaacc acuaaaccca     1080

ggaaaaugcg ccugcgaaug cacagaaagu ccacaaaaau gucuauuaaa agguaaaaaa     1140

uuccaucacc aaacauguuc augcuacaga agaccaugca caaacagaca aaaagcaugu     1200

gaaccuggau uuucauauuc agaagaaguu uguagaugug uuccaucaua cuggaaacga     1260

ccacaaauga gcuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  2493
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt12)

<400>  2493
gggagaaagc uuaccaugua cagagaaugg guaguaguaa acguauucau gaugcuauau       60

guacaacuug uacaaggaag cucaaaugaa cacggaccag uaaaaagauc aucacagucc      120

acacuagaaa gaucagaaca acaaauaaga gcagcauccu cucuagaaga auuacuaaga      180

aucacacauu ccgaagacug gaaauuaugg cgaugucgac uacgcuuaaa aagcuuuacu      240

aguauggacu cacgcucagc aucacauaga aguacaagau uugcagcaac auucuacgac      300

auagaaacac uaaaaguaau agaugaagaa uggcaaagaa cacaaugcuc accaagagaa      360

acaugcgucg aaguagcauc ugaacucgga aaauccacca auacauucuu caaaccacca      420

ugcguuaacg uauuuagaug cggaggaugu ugcaacgaag aaucacuaau augcaugaau      480

acauccacau cauacauauc aaaacaacua uucgaaauau ccguaccauu aacaucagua      540

ccagaacuag uaccaguaaa aguagcaaau cacacaggau gcaaaugccu accaacagca      600

ccaagacacc cuuacagcau aauaagaaga ucaauacaaa uacccgaaga agacagaugc      660

ucccacagca aaaaauuaug cccaaucgac augcuauggg acucaaacaa augcaaaugc      720

guacuacaag aagaaaaccc acuagcaggu acagaagacc acucacaccu acaagaacca      780

gcauuaugcg guccucacau gauguucgac gaagauagau gcgaaugcgu augcaaaaca      840

ccauguccaa aagacuuaau acaacaccca aaaaauugcu ccuguuuuga auguaaagaa      900

ucacuagaaa caugcugcca aaaacacaaa uuauuucauc ccgauacaug cucaugcgaa      960

gacagaugcc cauuccacac aagaccaugc gcaaguggaa aaacagccug cgccaagcac     1020

ugccgauucc caaaagaaaa aagagcagcu caaggaccac acucacgaaa aaauccauaa     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  2494
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt13)

<400>  2494
gggagaaagc uuaccaugga cucagacgaa acagguuucg aacacuccgg auuaugggua       60

ucaguauuag caggauuacu auuaggagca ugccaagcac auccaauacc agacucauca      120

ccacuucuac aauucggagg acaaguaaga caaagauacu uauacacaga ugacgcccaa      180

caaacagaag cacacuuaga aauaagagaa gacggcacag ucggaggagc agcagaccaa      240

ucaccagaau cuuuauuaca auuaaaagca uuaaaaccag gaguaauaca aauauuagga      300

guaaaaacau caagauuucu augccaaaga ccagacggag cauuauacgg aucauuacau      360

uucgacccag aagcauguuc auucagagaa uuauuacuag aagaugguua uaauguauau      420

caaucugaag cacacggauu accacuacau cuaccaggaa auaaaucacc acauagagac      480

ccagcaccaa gaggaccagc aagauucuua ccauuacccg gauuaccucc agcacuaccu      540

gaaccaccag gaauacuagc accacaacca ccagauguag gaucauccga cccauuauca      600

augguaggac caucacaagg aagaagucca ucauacgcau cauaaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  2495
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt13)

<400>  2495
gggagaaagc uuaccaugca cucauucccu ccacuauuau uauuacuauu uuggggagua       60

guaucacaca guuucccugc aaccuuagaa acacaagaac aagacguaga ccuaguucaa      120

aaauacuugg aaaaauacua caaccuuaaa aaugacggaa gacaaguaga aaaacgaaga      180

aauucaggac cagucguaga aaaacuaaaa caaaugcaag aauuuuucgg acuaaaaguu      240

acaggaaaac cagaugcaga aacacuaaaa guaaugaaac aaccuagaug uggaguaccc      300

gacguagccc aauuuguauu aacagaaggc aacccaagau gggaacaaac ccacuuaacc      360

uacagaauag aaaauuacac accagaucua ccuagagccg acguagauca ugcgauagaa      420

aaagcauuuc aauuauggag uaauguaacu ccacuaacau uuacaaaagu cucagaagga      480

caagcggaca uaaugauauc cuucguaaga ggagaucaca gagacaauag uccauucgac      540

ggaccaggcg gaaaccuagc acacgcuuuc caaccaggac ccggcauagg aggagaugca      600

cacuucgacg aagacgaaag auggacaaac aacuucagag aauauaaccu ccacagagua      660

gcugcacaug aacuaggaca uucauuagga cuuagccaca gcacagacau aggagcacua      720

auguacccuu cauauacauu uucaggagac guacaauuag cacaagacga uauagacgga      780

auacaagcaa uauauggaag aucacaaaau ccuguacaac cgaucggacc ucagacacca      840

aaagcaugcg auagcaaacu uaccuucgac gcuauaacaa caauuagagg cgaaguaaug      900

uucuucaaag accgauuuua caugagaaca aauccauucu aucccgaagu agaauuaaac      960

uuuauauccg uauuuuggcc acaacucccu aacggauuag aagccgcaua cgaauuugca     1020

gauagagacg aaguaagauu uuucaaagga aacaaauacu gggcuguaca aggacaaaac     1080

guacuacacg gauauccaaa agacauauac ucaucauucg gcuuuccccg aacaguaaaa     1140

cauauagaug cagcauuauc agaagaaaac acaggaaaaa cauauuucuu uguagccaac     1200

aaauacugga gauaugauga auacaaaaga ucaauggacc cagguuaccc aaaaaugaua     1260

gcacaugauu uuccaggaau uggacauaaa gucgacgccg ucuucaugaa agacggauuc     1320

uucuauuucu uucauggaac uagacaauau aaauucgacc caaaaacaaa aagaauauua     1380

acacuacaaa aagcaaacuc uugguucaac uguaggaaaa auuaaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  2496
<211>  1387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt13)

<400>  2496
gggagaaagc uuaccaugca cucauuucca ccauuacuac ucuuauuauu uuggggagua       60

guaucacacu cauucguacu aacagaagga aauccaagau gggaacaaac acaccuuacc      120

uacagaauag aaaauuacac accagaucua ccaagagcag acguagacca cgcaauagaa      180

aaagcauuuc aauuaugguc aaacguaaca ccauuaacau ucacaaaagu aucagaagga      240

caagcagaca uaaugauauc auucguaaga ggagaccaca gagacaauuc accauuugau      300

ggaccaggag guaaucuggc acacgcauuc caaccaggac caggaauagg aggagacgca      360

cacuucgacg aagacgaaag auggacaaac aacuucagag aauacaaccu acacagagua      420

gcagcccaug aacuaggaca cucacuagga cuaucacacu caacagacau aggagcccua      480

auguauccau ccuacacauu cucaggagac guacaacucg cgcaagacga cauugacgga      540

auccaagcua uauacggaag aucacaaaac ccaguacaac caauaggccc ccaaacacca      600

aaagcaugug acucaaaacu aacauuugau gcaauaacaa caauaagagg cgaaguaaug      660

uucuucaaag acagauucua caugcgcaca aauccauucu acccagaagu cgaauuaaac      720

uucauaucag uauucuggcc ccaauuacca aacggauuag aagccgccua cgaauuugca      780

gaccgagacg aaguaagauu cuucaaagga aacaaauauu gggcaguaca aggacaaaac      840

guauuacacg gauauccaaa agacauauac uccucauuug gcuuuccaag aacaguaaaa      900

cauaucgacg cagcacucuc cgaagaaaac acaggaaaaa cauacuucuu uguagcaaac      960

aaauacugga gauaugacga auauaaaaga ucaauggacc cgggauaccc aaaaaugaua     1020

gcacaugacu ucccaggaau aggacacaaa guagacgccg uauucaugaa agacggauuu     1080

uucuacuucu uucacggaac uagacaauac aaauucgacc caaaaacaaa aaggauacua     1140

acauuacaaa aagcaaacuc augguuuaac ugccgcaaaa acuaaggacu aguuauaaga     1200

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1380

cagaauu                                                               1387


<210>  2497
<211>  3574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt13)

<400>  2497
gggagaaagc uuaccaugaa gaaaaauaua cuuaaaauac ucauggacuc auacaguaaa       60

gaaagcaaaa uucaaacggu ucgaagagua accaguguca gccuauuagc aguauaucua      120

acuaugaaua cuagcagcuu aguacucgcg aaaccaauug aaaauacaaa ugacacaagu      180

auuaaaaaug uagaaaaauu gagaaaugca ccaaaugaag aaaacucgaa gaaaguagaa      240

gauagcaaaa augauaaagu ugagcauguu aaaaacauag aagaagcaaa agucgaacag      300

guggcuccag aaguaaaauc aaaaagcaca cucagaucag caaguaucgc aaacacgaac      360

agugagaaau augauuuuga auaccugaau ggccucucau auacagaauu aacaaacuua      420

auuaaaaaua uaaaauggaa ucaaaucaac ggcuuauuca auuacaguac cggaagucag      480

aaauucuuug gggacaaaaa ccgaguacaa gcaauaauua augcauuaca agaaucaggg      540

cgaacauaua cagccaacga uaugaaagga auugaaacau ucaccgaggu uuuacgagcu      600

ggcuucuauu ugggcuacua caacgaugga cuauccuauu ugaacgauag aaacuuucag      660

gauaaaugua uaccagcaau gaucgcaaua cagaagaacc caaacuucaa auuaggaaca      720

gcaguacaag augaaguaau uaccagucuu gguaaauuaa uuggaaacgc aagcgcgaau      780

gcugaaguug uaaauaacug ugucccaguc uuaaaacaau uuagagagaa uuuaaaucaa      840

uaugcaccag auuacguuaa aggaacagcg guuaaugaau uaauaaaagg aauagaguuc      900

gacuuuagcg gagcagcuua cgaaaaagac guaaaaacua ugccuuggua cggaaagauu      960

gauccauuca uaaacgaauu aaaagcauug ggccucuacg gaaauauaac aucagcuaca     1020

gaaugggcca gcgauguggg uauauacuau cuuaguaaau ucggucuuua uaguacaaac     1080

aggaaugaua ucguucaauc acuagaaaaa gcaguagaua uguauaaaua cggaaaaaua     1140

gcauuugugg caauggaaag aauaacaugg gacuaugaug gaauaggauc uaacggcaag     1200

aaaguagacc augacaaauu ucucgacgau gccgaaaaac acuacuuacc aaaaacguau     1260

acauuugaca auggaacauu uaucauaaga gcgggugaca aaguaaguga agagaaaaua     1320

aaaagacuau acugggcauc uagagaagua aaaucucaau uucacagggu cgucgggaau     1380

gacaaagcac uagaaguagg aaacgccgac gauguccuca caaugaaaau auucaacagc     1440

cccgaagaau auaaauucaa uacuaauaua aauggaguua gcacagacaa uggcggauua     1500

uauauagaac cacgagggac uuucuacacg uaugaaagaa caccacaaca aucaauauuc     1560

agcuuagaag aacuguuuag acaugaauau acucauuacu uacaagcucg auauuuagug     1620

gauggauuau ggggacaagg ccccuucuac gagaaaaaca gacuaacuug guucgacgaa     1680

ggaacagcag aguucuucgc cggcucaacc aggacaucag gagugcuucc gagaaaauca     1740

auacuaggcu aucuugcaaa agauaaagua gaccacagau acagccucaa gaaaacauua     1800

aauucaggau augaugauag cgauuggaug uuuuauaauu auggguuugc uguagcccac     1860

uauuuauaug aaaaagauau gccaacauuu auaaaaauga auaaagcaau ucuaaauacc     1920

gacguuaaaa gcuaugauga aauaauaaag aaauuaucag acgacgcgaa caaaaacaca     1980

gaauaucaaa aucacauaca agaauuagcc gacaaauauc aaggagcagg cauacccuua     2040

gugucagacg acuauuuaaa agaucaugga uauaagaaag cguccgaagu auauucugaa     2100

auaucuaaag cggcaagccu aacaaauaca uccguaacag cggaaaaauc acaauacuuu     2160

aauacauuua cacuaagagg aacauauaca ggagaaacaa guaaaggcga auuuaaagac     2220

ugggacgaaa ugagcaagaa acuggacgga acacuagaaa gccuagcuaa aaacucaugg     2280

agcggauaua aaacauuaac ggcauauuuu accaauuacc gaguaacguc cgacaacaaa     2340

guacaauaug acguuguauu ucacggcguu uuaacagaua acgcagauau aaguaauaac     2400

aaagcaccaa uagcaaaagu uacaggccca ucgacaggug ccguagguag aaacauugaa     2460

uuuucuggaa aagauucaaa agaugaagau ggaaaaaucg uaucauacga cugggacuuu     2520

ggagacggag caacaucaag agggaaaaau ucaguccaug cauacaagaa agcuggaaca     2580

uauaacguaa cauuaaaagu uaccgaugau aaaggugcga cagcaacuga aucuuuuaca     2640

aucgaaauca aaaacgaaga uacaacaaca ccaauaacga aagaaaugga acccaaugac     2700

gauauaaaag aagcuaaugg accaauaguc gaaggaguaa ccgucaaagg ugaccuaaac     2760

ggcuccgacg acgcugauac auucuauuuu gauguuaaag aagauggaga ugugacaaua     2820

gaacuaccau auucaggauc uaguaacuuu accuggcugg uauauaaaga aggcgaugau     2880

caaaaucaua ucgcuagugg uauagacaaa aauaacagca aaguuggaac auuuaaaagc     2940

acaaaaggua gacauuacgu auucauuuac aaacacgauu cagcaucaaa uaucucauac     3000

ucuuuaaaua uaaaaggcuu agguaaugaa aaacugaaag agaaagaaaa uaaugauucg     3060

ucagacaaag cuacagugau accaaauuuc aauacaacua ugcaaggauc acugcuagga     3120

gaugacagcc gugauuauua cagcuucgaa guaaaagaag aaggagaggu aaacaucgaa     3180

uuagauaaga aagaugaauu uggaguaaca uggacauuac auccagaauc caacauaaac     3240

gacagaauaa cauacggaca aguugauggu aacaaaguaa guaauaaagu aaaauugagg     3300

ccuggaaaau acuaccuguu aguauauaaa uacagugggu caggaaacua cgaacuacga     3360

guuaacaaau aaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     3420

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     3540

ccccccaaag gcucuuuuca gagccaccag aauu                                 3574


<210>  2498
<211>  3298
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt13)

<400>  2498
gggagaaagc uuaccaugaa auggguaacu uuuauaaguc uucuauuucu auuuucaucg       60

gcauauagua uagcaaacac aaacucagaa aaauaugacu uugaauaucu aaauggauua      120

ucauauacag aauuaacaaa ccugaucaaa aacauaaaau ggaaucaaau aaacggauua      180

uuuaacuaua gcacgggauc acagaaauuu uucggcgaua aaaauagagu acaagcaauu      240

auaaaugcuc uccaagaauc uggcagaacg uauacagcaa acgauaugaa aggaaucgaa      300

acuuuuacag aaguccugag agcagguuuu uacuuagguu auuacaacga cgggcuaagc      360

uaucuaaaug auagaaacuu ccaagacaaa uguauaccag caaugauugc aauacagaaa      420

aaccccaauu uuaaauuagg aacagcaguu caagacgaag uuauaacauc ucuuggcaaa      480

cuuauaggga acgcaagcgc aaacgcagaa guaguaaaca acuguguacc gguauuaaaa      540

caauucagag aaaauuuaaa ucaauacgca ccagacuaug uaaaaggaac agcaguaaac      600

gaacuaauaa aaggaauaga auuugauuuc agcggagccg cauaugaaaa ggaugucaaa      660

acuaugccgu gguacggaaa aauagaccca uuuauaaaug aacuuaaagc acuagguuua      720

uacggaaaca ucacaagcgc aacugaaugg gcaucagaug uuggaauuua uuaccuaucu      780

aaauuuggac uauacucaac caacaggaac gauauagugc aaucucugga aaaagcugua      840

gacauguaua aauauggaaa aauagcuuuc gucgcaaugg aaagaauaac uugggauuau      900

gaugguauug gaucaaacgg caaaaaggua gaucacgaua aauucuuaga ugacgcagaa      960

aagcacuacu uaccaaaaac guauacauuc gacaacggga cuuuuauaau cagagcaggc     1020

gauaaaguau ccgaagagaa aauaaaaaga uuauacuggg cuucaaggga aguaaaaucu     1080

caauuccacc gaguaguagg aaaugauaaa gcauuagaag uggguaacgc ugaugaugua     1140

uuaacaauga aaauauucaa cagcccugaa gaauacaagu ucaauacaaa uauaaacgga     1200

gucucuaccg auaacggagg cuuauacauu gaaccaagag gaacauuuua cacauaugaa     1260

agaacuccac aacaaagcau auucagccuu gaggaacuau uccgacacga auauacacau     1320

uacuuacaag ccagguaucu uguagaugga cuuuggggac agggaccuuu cuaugaaaag     1380

aauagacuaa ccugguucga cgaaggaaca gcagaguucu uugcagguuc aacaagaaca     1440

ucuggaguau uaccacgaaa aucaauucuc gguuauuuag caaaagauaa aguagaucau     1500

agauauucac uaaagaaaac cuugaacuca ggauacgacg acagugacug gauguucuac     1560

aauuacggau uugcaguagc acacuauuua uaugaaaaag auaugccuac auucauuaaa     1620

augaacaaag caauacuaaa uaccgaugug aaaagcuaug acgaaauaau aaagaaacuu     1680

ucagacgaug cgaacaaaaa uacagaauac caaaaccaua uucaagaacu cgccgacaaa     1740

uaccaaggug caggcauucc ucuaguaagu gacgacuauu uaaaagacca uggauacaag     1800

aaagcaucag aagucuauuc agaaaucagc aaagccgcau ccuuaacuaa uacaagcguc     1860

acagcagaga aaucacaaua cuuuaauaca uucacgcuuc gaggaacuua uacaggugaa     1920

acgucaaaag gagaguuuaa agauugggau gaaaugucaa agaaauuaga uggaacacua     1980

gaaucguuag cuaaaaacuc auggucugga uauaaaacac uaaccgcaua cuuuacuaac     2040

uacagaguua ccagugauaa caaaguacaa uacgauguag uauuucaugg aguacuaaca     2100

gacaaugcag acauuagcaa uaacaaagca ccaauagcaa aaguuaccgg ccccucaaca     2160

ggggcaguag guagaaauau ugaguucucu ggaaaagaua gcaaagauga agauggaaaa     2220

auaguuucau augauuggga cuuuggugau ggagcaacua gcaggggcaa aaacucaguu     2280

cacgcauaca agaaagcagg aacauauaac guaaccuuaa aaguaaccga ugauaaagga     2340

gcaaccgcca ccgaaaguuu uacuauagaa aucaaaaacg aagacacaac gacaccaaua     2400

acaaaagaaa uggaaccaaa ugacgacaua aaagaagcaa acggaccaau aguagaagga     2460

guaacaguaa aaggagaccu aaauggcucg gacgaugcag auacauuuua cuuugauguc     2520

aaagaggaug gugacguaac cauagaacua cccuauagcg gaucaaguaa uuucacuugg     2580

cuaguuuaca aagaaggaga ugaccaaaac cauauugcau caggaauuga uaaaaacaac     2640

ucaaaaguag gcacauucaa aucaacaaaa ggacgacauu acguuuucau auauaaacac     2700

gacagcgcuu caaacauauc auauucucuc aacauaaaag guuuaggcaa ugaaaaauua     2760

aaagaaaaag aaaauaacga cucaucagau aaagcaaccg uaaucccaaa uuucaauaca     2820

acgaugcaag gaucgcuccu cggagaugac agucgugauu acuacucauu ugaaguaaaa     2880

gaagaaggag aaguuaauau agaacuagau aagaaagacg aguucggagu aacauggaca     2940

uuacacccag agaguaauau caacgauaga auuacauaug gccaaguuga cggaaauaaa     3000

guuaguaaua aaguaaaacu uaggccagga aaauauuacc ugcucgucua caaauacuca     3060

gguagcggua acuaugaacu aagaguaaac aaauaaggac uaguuauaag acugacuagc     3120

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3240

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3298


<210>  2499
<211>  3646
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt13)

<400>  2499
gggagaaagc uuaccaugaa auggguaaca uucauuagcc ucuuauuucu auuuucauca       60

gcauacagua ugaagaaaaa uauacuaaaa auauugaugg acuccuauag uaaagagagc      120

aaaauacaaa caguaaggcg aguaaccagc gugaguuuac uugcuguaua ucuaacaaug      180

aacacaagua gccuaguuuu agcaaaacca auagaaaaua cgaaugauac cuccaucaaa      240

aacguagaaa aacuaagaaa ugcaccaaac gaagaaaauu caaagaaagu agaagauagu      300

aaaaacgaca aaguagaaca ugugaaaaac auagaagaag ccaaaguaga acaaguagca      360

ccagaaguca aaucuaaauc cacuuuaaga agugcgucaa ggagaagaag aaaaagaaua      420

gcaaacacaa auagugaaaa auacgauuuc gaauaccuaa acggacuauc cuauacugaa      480

cuaacaaauc uaauuaaaaa cauaaaaugg aaucaaauaa acgguuuauu uaacuauucc      540

acaggcucac aaaaauuuuu cggagauaaa aaucgcguuc aagcaauaau aaaugcccua      600

caagaaagcg ggagaaccua caccgcaaau gauaugaaag gaauagaaac auucacagaa      660

guacuuagag ccgguuucua ucuagguuac uauaacgacg gauuaaguua ucuaaaugau      720

aggaacuucc aagauaaaug cauaccagca augaucgcaa uacagaaaaa uccaaauuuc      780

aaauugggaa cagcagucca agacgaagug auaacaucac uaggaaaacu aauaggcaac      840

gcaagugcaa acgccgaagu aguaaacaac uguguuccag uacuaaaaca auucagagaa      900

aaccuaaacc aauacgcacc ugauuauguu aaagguacag ccgucaacga acucauaaaa      960

gguauagagu ucgacuucuc aggagcagcg uacgaaaaag auguaaaaac aaugccaugg     1020

uauggaaaaa uugauccauu uauuaaugaa uuaaaggcau uaggauugua cggaaacaua     1080

accucggcua cagaaugggc aucagaugua ggaauauacu accuuucaaa auuuggucua     1140

uauagcacaa accggaacga uauaguacaa ucauuagaaa aagccguaga cauguauaaa     1200

uauggaaaaa uagcauuugu cgcaauggaa agaauaaccu gggacuacga cggaauaggg     1260

ucuaacggga agaaaguaga ccaugauaaa uuucucgaug augccgaaaa acauuaucua     1320

ccuaaaacuu acacuuucga caauggcaca uucauaauca gagcuggcga caaaguaucc     1380

gaagagaaaa uaaaaagauu auauugggca ucuagagagg uaaaaaguca guuucacaga     1440

gucguaggaa augauaaagc ucuugaggua ggaaacgcag augacguguu aacaaugaaa     1500

auauuuaauu caccggaaga auacaaguuc aauacaaaca uuaauggcgu auccacagac     1560

aauggaggac uauauaucga accacgagga acauucuaua cauaugaaag aaccccacaa     1620

cagaguauuu ucagucuaga agaauuauuu aggcacgaau acacccauua uuuacaagca     1680

cguuaucuag uagacggacu auggggucag ggacccuucu acgaaaagaa ccgcuuaaca     1740

ugguucgaug aagguacugc ggaauuuuuc gcuggaucaa cacgaaccag uggaguacuc     1800

ccaagaaaau caauuuuagg uuaccuugca aaagauaaag ucgaucacag auacucacuc     1860

aaaaagacac uaaauucagg auaugaugac ucagacugga uguuuuauaa uuauggauuc     1920

gcagucgcac acuaccucua cgaaaaagau augccaacgu ucauuaagau gaauaaggca     1980

auacuaaaua cagauguaaa aucauacgac gaaaucauaa agaaacuauc cgacgacgca     2040

aauaaaaaua cagaauacca aaaccauaua caagaacuag cagacaaaua ucagggagca     2100

ggcaucccac uuguaagcga cgacuacuug aaagaccacg gauacaagaa agcauccgaa     2160

gucuacucag aaauauccaa agcagccuca uuaacaaaua cguccguaac ugcugagaaa     2220

agucaauauu ucaacacauu cacacuacgu ggaacauaca ccggcgaaac gaguaaagga     2280

gaguucaaag auugggacga aaugucaaag aaauuagacg guacacuaga aucauuagcc     2340

aaaaauucau ggagcggaua caaaacucuu acggcauacu uuacaaacua uaggguuaca     2400

agugauaaca aaguacaaua ugacguagua uuucauggag uccucacaga caaugcugau     2460

aucagcaaca acaaagcucc uaucgcuaaa guaacugggc ccaguacggg agcaguaggc     2520

agaaacauug aguucucagg aaaagacuca aaagacgaag auggcaaaau aguauccuau     2580

gauugggacu uuggagaugg agcaacauca agaggcaaaa acucagucca cgcauacaag     2640

aaagcaggaa cauauaaugu aacacuuaaa guaacagacg auaaaggcgc aacagcaaca     2700

gaaucauuca caauagaaau uaaaaacgaa gauacaacaa caccaauaac aaaagaaaug     2760

gaaccaaacg augauauaaa agaggcaaac gguccaauag uggaaggagu aacaguaaaa     2820

ggcgacuuga augggagcga cgacgccgac acauuuuauu ucgacguuaa agaggacggc     2880

gacguaacaa uagaauuacc auacagugga ucaagcaacu uuacguggcu aguuuauaaa     2940

gaaggagacg accaaaacca uauagcaagu gguauagaca aaaacaauag uaaaguaggu     3000

acauuuaaaa guaccaaagg cagacauuac guauuuauau acaaacacga uucagcauca     3060

aacauaucau auucucuaaa uauaaaagga uuagggaaug aaaaacuuaa agaaaaagag     3120

aauaaugaca gcagcgacaa agcaacuguc auacccaacu uuaacacaac aaugcaaggu     3180

ucacuauuag gagacgacag ucgagauuau uauagcuucg aaguaaaaga ggaaggagaa     3240

gucaauauag aauuagauaa gaaagacgaa uuuggaguaa cauggacacu ucauccugaa     3300

aguaauauaa acgauagaau aacauacgga caaguagacg gaaacaaagu cucaaauaaa     3360

guaaaacuua gaccagggaa auauuaucua cuuguauaua aauacagugg aucagguaac     3420

uaugaacuaa gagucaauaa auaaggacua guuauaagac ugacuagccc gaugggccuc     3480

ccaacgggcc cuccuccccu ccuugcaccg agauuaauaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3600

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    3646


<210>  2500
<211>  3322
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt13)

<400>  2500
gggagaaagc uuaccaugaa cuucuugaaa auaauccuca acagaggaaa aaccaugaaa       60

cgaaaauguc ugucaaaaag auuaaugcua gcuauaacaa uggccaccau auucacaguc      120

aacucaacac uaccaaucua ugcagcagua gauaaaaaua augcuacagc ugcaguacaa      180

aacgaaucaa aacguuauac aguuucguac uuaaaaacau uaaauuauua ugaccucguc      240

gaucuauugg uaaaaacaga aaucgaaaau uuaccagauu uauuccaaua cagcucagau      300

gcuaaagagu ucuaugguaa caaaacaaga augagcuuca uuauggacga aauagguaga      360

agggcuccac aauauacaga aauagaccau aaaggaauac caacccuagu agaaguaguc      420

agagccggau uuuaucuugg auuccacaac aaagaauuaa augaaaucaa caaaagauca      480

uucaaagaac gaguaauccc aagcauauua gcaauacaaa agaauccaaa uuucaaauua      540

ggaacagaag uucaggacaa aauaguuagc gcaacaggac uucuagccgg aaaugaaaca      600

gcaccuccug aaguaguaaa uaacuuuaca ccaauauugc aggauugcau aaagaacaua      660

gauagauacg cguuagauga ccuaaaaucu aaagccuuau ucaaugugcu ugcagcccca      720

acauacgaca ucacugaaua ucuccgagcc acaaaagaaa aaccagaaaa cacaccaugg      780

uacgggaaaa uagacggauu cauaaacgaa cucaagaaac uagcauuaua ugguaaaaua      840

aacgacaaca acucauggau cauagacaau gguauauacc auauagcccc auuaggaaaa      900

cuucacagca auaauaaaau aggaauagag acauuaacag aaguaaugaa aguauacccu      960

uauuuaagua ugcaacauuu acaaucagca gaccaaauca aaagacauua cgacaguaaa     1020

gacgcggaag gaaacaaaau uccauuagac aaauuuaaaa aggaaggaaa agaaaaauau     1080

uguccaaaaa ccuacacauu ugacgaugga aaagucauua uaaaagccgg agcacgugua     1140

gaggaagaaa aagugaaaag acuuuacugg gcauccaaag aaguaaauuc acaauucuuu     1200

cgaguuuacg gaauugacaa accccuggaa gaaggaaacc cagacgacau uuuaacgaug     1260

guaauauaca acaguccuga agaauacaaa cuaaacagug uacuauaugg cuacgauacg     1320

aacaacggag gaauguacau cgaaccagaa ggaacauucu uuacguacga aagagaagca     1380

caggaaucaa cuuauacacu agaggaacua uuucgacacg aauacacaca cuaucuccaa     1440

gguagauaug caguuccggg acaaugggga agaacuaagu uauacgauaa ugacagacua     1500

acaugguaug aagaaggagg ggccgaguua uucgcgggca guaccagaac aagugggaua     1560

uuacccagaa aaagcauugu auccaacaua cacaacacca cgaggaauaa ccgauauaaa     1620

cuuucagaua caguccauuc aaaauaugga gcaucguuug aguucuacaa uuaugcaugc     1680

auguuuaugg auuauaugua uaauaaagac augggaauac ucaacaaauu aaaugaccua     1740

gcaaagaaca augacgugga cggauacgac aacuacauaa gagaccuauc aagcaacuac     1800

gcacuaaaug acaaauauca agaccacaug caagaaagaa uagauaacua ugaaaaucuc     1860

acaguaccuu ucguugcaga ugacuaccua guccgucaug cauacaaaaa uccgaacgaa     1920

auauauucag aaauuucaga aguugcuaaa cuuaaagaug ccaaaucaga aguaaagaaa     1980

agucaauacu ucaguacuuu uacacuacgc ggaagcuaca cuggaggagc uucaaaagga     2040

aaauuagaag accaaaaagc caugaacaaa uucauagacg auagccucaa gaaauuagau     2100

acguauaguu ggucuggaua uaaaacacua acagcguauu uuacaaauua uaaagucgau     2160

aguagcaaca gaguaacaua cgauguagua uuucauggau auuuaccaaa ugaaggagau     2220

uccaaaaauu cacucccgua uggaaaaaua aacgguacau auaaagggac agaaaaagag     2280

aaaauaaaau ucagcucaga aggaaguuuu gacccggacg guaaaauagu aaguuacgaa     2340

ugggacuucg gugacggcaa uaaaucaaac gaagaaaauc cagaacacuc uuaugauaaa     2400

guaggaaccu acacagugaa auuaaaagua acagaugaua aaggugaauc auccgucagu     2460

acgacaacag cagaaauaaa agaucuguca gaaaacaagc ucccgguuau auauaugcau     2520

guaccaaaaa gcggcgcccu aaaucaaaaa guagucuuuu acggaaaagg aacguaugac     2580

ccagacggaa guauagcagg auaccaaugg gauuuugggg augguaguga cuuuagcagc     2640

gaacaaaacc caucacaugu cuacacuaag aaaggcgagu acacaguuac acucagagua     2700

auggacucaa guggacaaau gucagagaaa acaaugaaaa uaaaaauaac agauccagua     2760

uauccaauug gaacugaaaa agaaccaaac aauucuaaag aaacagccuc aggucccauu     2820

gucccuggca uaccuguaag uggaacaaua gaaaacacca gugaccaaga cuauuucuau     2880

uuugacguua uaacacccgg cgaaguaaaa auagacauca acaaacuugg auacggagga     2940

gcuacauggg uuguauauga ugaaaacaau aaugcaguaa guuaugcaac ugaugaugga     3000

caaaaccuaa gcggaaaauu uaaagcagau aaacccggac gauauuauau acacuuauau     3060

auguucaacg gaaguuauau gccauaucga auaaauauag aaggaagcgu aggaagauaa     3120

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     3180

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3300

ucuuuucaga gccaccagaa uu                                              3322


<210>  2501
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt13)

<400>  2501
gggagaaagc uuaccaugaa aagaaaaugu uuaagcaaaa gauuaaugcu agccauuaca       60

auggcaacaa uuuucacagu aaauaguaca uuaccaauuu acgcagcugu cgacaaaaac      120

aacgcaacug cagcaguaca gaacgaauca aaacgguaua cagugagcua ccucaaaaca      180

cuaaauuauu augaccuagu agaucuacuu guaaaaacag aaauugaaaa ucuaccagac      240

cuauuccaau acuccucaga ugcaaaggaa uuuuauggaa acaaaacgcg caugaguuuc      300

auuauggacg aaauaggaag gagggcccca caguacacag aaauagauca uaaaggcaua      360

ccaacgcuag uagaagucgu aagagcagga uuuuaccuag guuuucacaa caaagaacuc      420

aacgaaauaa acaagcgcag uuuuaaagaa agagucauuc caucaauauu agcgauccag      480

aaaaacccua acuucaaacu aggaacagaa guacaagaca aaauuguauc agcgacagga      540

cuacuagcag gaaaugagac agcaccacca gaaguaguaa auaauuucac accaauauua      600

caagacugca ucaaaaauau agaccgauac gcauuggaug acuugaaaag caaagcauua      660

uuuaauguac uugcggcacc aacauaugac auaacagaau accuaagagc uacaaaggaa      720

aaaccagaaa acacaccaug guauggaaaa auagacggau uuauaaauga acugaaaaag      780

uuagcacuau acgguaaaau caaugacaac aacagcugga uaauagacaa ugggaucuac      840

cauauagccc cauuagguaa acuacauuca aacaacaaaa uaggaaucga aacccuaaca      900

gaaguaauga aaguauaucc auaccuaagc augcaacacu ugcaaagcgc agaccaaaua      960

aaaaggcacu augacagcaa agaugcagaa ggaaacaaaa uaccacucga caaguucaag     1020

aaagaaggua aagaaaaaua uugucccaaa acguauacgu ucgaugacgg aaaaguaauc     1080

auaaaagcag gagccagagu agaagaagaa aaaguaaaaa gacuuuauug ggcuucgaaa     1140

gaagucaaca gccaauucuu cagaguauau gguaucgaca aaccucuaga agaaggaaau     1200

ccagaugaca uucuaacaau gguaauauac aacucaccgg aggaauacaa auuaaacagu     1260

guccuguacg gauacgauac aaacaacggu ggcauguaua uagaaccaga agguacauuc     1320

uucacuuaug aaagagaagc ucaagaaagc accuacacau uagaggaauu auuuagacau     1380

gaauauacuc acuauuuaca aggccgauau gcaguaccag gccaaugggg gcguacaaaa     1440

uuauacgaua acgauagauu aacaugguau gaagaaggug gagccgaacu auucgcaggu     1500

uccaccagga cuucaggaau acuaccaagg aaaucaauug uaaguaauau acacaauacc     1560

acacguaaca acagauacaa auuauccgac acaguacacu caaaauacgg agcaucauuc     1620

gaguucuaca auuacgcaug uauguuuaug gauuauaugu auaauaaaga uaugggaauc     1680

cuaaacaaac uaaaugacuu agcuaaaaau aaugacguug acggauacga caauuacaua     1740

agggacuuaa guagcaacua cgcauuaaac gacaaauacc aagaccauau gcaagaaaga     1800

auagauaacu augaaaaucu aacgguacca uuuguugcag acgauuauuu agucagacau     1860

gcauacaaaa acccuaauga aauauacagu gaaauaucag aaguggcaaa acuaaaagac     1920

gcuaaaucug aaguaaagaa aagccaauac uuuaguacau ucacacuucg aggcucauac     1980

acaggaggag caagcaaggg uaaacucgaa gaccaaaaag caaugaacaa auuuauagau     2040

gauucacuaa agaaauuaga cacauauagu uggagcggcu auaaaacacu aaccgcauac     2100

uuuacuaacu auaaaguaga cucaucaaac cgcguaacau acgacguagu auuucacgga     2160

uaccucccca augaagguga cagcaaaaac ucacuacccu augggaaaau aaaugggaca     2220

uacaaaggua ccgaaaagga gaaaauaaaa uuuucuucug aaggcagcuu cgacccagac     2280

ggaaaaauag ucuccuacga augggacuuc ggugauggaa acaaaagcaa ugaagaaaau     2340

ccagaacaca guuacgacaa aguagggacu uacacuguaa aacugaaagu uacagaugac     2400

aagggcgaaa gcucuguaag uacaaccacu gccgaaauaa aagaccuauc agaaaacaaa     2460

cuuccaguaa uauauaugca cguuccuaaa ucuggagcuu ugaaccaaaa aguaguuuuc     2520

uacggaaaag gcacguauga cccggaugga ucaaucgcag gcuaucaaug ggacuuuggc     2580

gauggaagug acuuuuccag cgaacaaaac ccuagccacg ucuauacuaa gaaaggagaa     2640

uauaccguga cauuacgagu aauggauuca ucaggacaaa ugucagagaa aaccaugaaa     2700

auaaaaauca cugacccagu auauccaaua ggaacagaaa aagaaccaaa caacaguaaa     2760

gaaacagccu cagguccaau aguaccugga auaccagucu caggcacaau agaaaacaca     2820

ucagaccaag acuacuucua uuuugauguu auaacaccag gugaagucaa aauagauaua     2880

aauaaauuag gauauggugg ugcaacaugg gucguauacg augaaaacaa uaacgccguu     2940

aguuacgcaa cagacgaugg ucaaaaccua ucugggaaau ucaaagcaga uaaaccugga     3000

agauacuaua uacaucuaua uauguuuaac ggcagcuaca ugccauauag aauaaauaua     3060

gaagggucag uaggaagaua aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  2502
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt13)

<400>  2502
gggagaaagc uuaccaugaa auggguaacu uuuauaucau uauuauuccu auucaguuca       60

gcauauagug uacaaaauga aucaaaaagg uacacaguau ccuaucuaaa aacguuaaau      120

uauuacgauu uaguagaucu ccuagucaaa acugaaauag aaaacuuacc agaccuauuc      180

caauauucgu ccgaugcaaa agaauuuuau ggaaauaaaa cccgaauguc auucaucaug      240

gacgaaauug gacgaagggc accgcaauac acagaaauag aucacaaagg uauuccaacc      300

cucguagaag ucguaagagc uggcuucuac cuaggauuuc auaauaaaga auuaaaugaa      360

auaaacaaaa ggucauucaa agaaagagua auacccucca uauuagcaau acaaaaaaau      420

ccuaacuuua aacuuggaac agaaguucaa gacaaaaucg uuucagcgac cgguuuacug      480

gcaggcaacg aaacagcacc ucccgaaguc guaaacaacu ucacaccaau uuuacaagau      540

uguauaaaaa auauugaucg auacgcuuua gacgaccuua aaagcaaagc gcuauucaac      600

guacucgcag caccuacaua cgauaucacc gaauaccuuc gagcuacaaa agaaaaacca      660

gaaaauacuc cuugguaugg caaaauagac ggauucauaa acgaauuaaa aaaauuagcu      720

uuauauggaa aaauuaauga uaauaacuca uggauaauag acaauggaau auaucacauu      780

gcaccauuag gaaaauuaca uucuaauaau aaaauaggaa uagaaacauu gacagaagua      840

augaaagugu accccuaccu aagcaugcaa cauuuacagu cagcugauca aauuaaacga      900

cacuacgauu caaaagacgc agaaggcaau aaaaucccac uugacaaauu caaaaaagaa      960

ggaaaagaaa aauacugucc aaaaacauau acauuugacg acggaaaagu aauaauaaaa     1020

gcuggugcaa gaguagaaga agaaaaaguc aaaagacuau auugggcaag caaagaagua     1080

aauucacaau ucuuucgagu auauggaauu gacaaacccc uagaagaggg aaacccagac     1140

gauauacuaa caauggugau auacaacuca ccagaagaau auaaacuaaa caguguacua     1200

uacggauacg auacaaacaa uggcgggaug uacauagaac cagaagguac auucuucacg     1260

uaugaaaggg aagcacaaga auccaccuac acacucgaag aacuauucag acaugaauac     1320

acucauuauc uacaaggcag auaugccgua ccgggacaau ggggaagaac aaaauuauau     1380

gacaacgaca gauuaacaug guaugaagaa ggaggagcag aacuauuugc uggcaguacc     1440

agaacaagug ggauccuucc cagaaaauca auugugagua acauacacaa cacaacgaga     1500

aauaauagau auaaacuaag cgauaccgua cauaguaaau auggagccuc guucgaauuu     1560

uauaauuaug ccuguauguu cauggauuac auguauaaca aagauauggg uauauuaaau     1620

aaauuaaacg accucgcuaa aaauaaugau guagacggau acgacaacua cauaagagau     1680

uuauccagca acuaugcauu aaaugacaaa uaucaagacc acaugcaaga aagaaucgac     1740

aacuaugaaa aucuuacugu accauucgua gcagacgauu accuaguuag acacgccuau     1800

aaaaauccca acgaaauaua uagcgaaaua ucugaaguag caaagcuaaa agacgcaaaa     1860

agcgaaguga aaaaaucaca auacuuuuca acuuucacau ugagaggcuc auacacagga     1920

ggugcaagca aaggaaaauu agaagaucaa aaagcaauga auaaauuuau agacgacagu     1980

cuaaaaaaau uagauacaua cucaugguca gguuacaaaa cacuaacggc auacuucaca     2040

aacuauaaag uagauuccuc aaauagagua acauacgaug ucguuuuuca uggauaucua     2100

ccuaacgaag gagacagcaa gaauagucua ccauauggaa aaauaaaugg aacguacaaa     2160

ggaacugaaa aagaaaaaau caaauucuca ucagaaggca guuucgaucc cgacgggaaa     2220

auaguaucau acgaauggga uuuuggagau ggcaacaaau caaacgaaga aaacccagaa     2280

cauucauaug auaaagucgg aaccuacaca guaaaacuaa aaguaaccga ugacaaggga     2340

gaaucaucgg uuuccaccac gacagcugaa auaaaagacu uaucagaaaa caaauuaccc     2400

guaauauaca ugcacguacc aaaaucaggc gcgcuuaacc aaaaaguggu uuucuaugga     2460

aaaggcacau acgauccaga uggaagcauc gcaggauacc agugggauuu cggagauggu     2520

ucagauuuua guucugaaca aaauccuagc cauguauaca ccaaaaaagg ugaauacaca     2580

guuacacuua ggguuaugga cuccucagga caaaugagcg aaaaaacaau gaaaauaaaa     2640

auaaccgacc caguauaccc aauaggaacc gaaaaggaac caaacaauuc uaaagaaaca     2700

gcaucagguc caauaguacc aggaauccca gugucaggga caauagaaaa cacaucagac     2760

caagacuauu ucuauuucga cguaauaaca cccggagaag uaaaaauaga cauaaacaaa     2820

uuaggauacg guggcgccac uuggguugua uaugacgaaa acaacaacgc aguaucuuau     2880

gcaacugacg acggccaaaa cuuaagugga aaguuuaaag ccgauaaacc uggacgauac     2940

uacauacacc uauacauguu caacggcagu uacaugccau acagaauaaa cauagaaggu     3000

agcguugguc gauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2503
<211>  3355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt13)

<400>  2503
gggagaaagc uuaccaugaa auggguaaca uucaucagcu uacuauuuuu auuuucaucu       60

gccuauucca ugaaaagaaa augucuauca aaaagauuaa uguuagcaau aacaauggcu      120

acaauauuca cggucaacag uacacuccca auauacgcug cagucgacaa aaacaacgcg      180

acugcagcac gcaggcgcag aaaaagagua cagaaugaau caaaacgaua caccgugucg      240

uaccuaaaaa cccuaaauua cuacgaccuc guugaccuau uaguaaaaac agaaauagaa      300

aauuuaccag accuuuuuca auacucaagc gaugccaagg aauuuuacgg aaauaaaaca      360

aggaugaguu ucauaaugga ugagaucggc cgccgagcac cacaauauac cgaaauagau      420

cauaaaggaa ucccgacguu gguugaaguu guuagagcag gauucuauuu ggguuuucac      480

aacaaagaac uaaaugaaau aaauaaacgc agcuucaaag aaagaguaau accaagcauc      540

uuagcgauuc agaaaaaucc uaauuucaaa cuaggaacgg aaguacaaga caaaaucguc      600

ucagcaacgg gauuguuagc gggaaacgaa accgcuccac cagaagucgu aaacaacuuu      660

acccccauac uacaagacug caucaaaaau auagauagau acgcauuaga ugauuuaaaa      720

ucuaaagcau uauucaacgu auuggcggca ccaacauaug auauaacaga auauuuaaga      780

gcgacaaaag aaaaaccaga aaacacucca ugguauggca aaauugacgg auuuauaaau      840

gaauuaaaga aauuggcccu auacggaaaa auaaaugaca auaacagcug gaucauugac      900

aacggaauau accacauagc ucccuuagga aaacuacaua guaacaauaa aaucgguaua      960

gaaacauuaa cugaaguaau gaaaguuuac ccauaucuaa guaugcaaca uuuacaauca     1020

gcagaucaaa uaaaaaggca cuaugauagc aaagacgcag agggaaacaa aauaccacua     1080

gacaaauuua agaaagaggg aaaagaaaaa uacuguccaa aaaccuacac auucgaugac     1140

ggaaaaguaa ucauaaaagc aggagcaaga guagaagagg aaaaaguaaa acgauuauau     1200

ugggcaucua aagaaguuaa uucucaauuc uucagaguau acggaauaga caaaccacua     1260

gaagaaggca auccagacga cauauuaaca augguaauuu acaacagucc ugaagaauau     1320

aaauuaaauu caguauuaua uggauacgac acaaacaaug gaggaaugua caucgaaccc     1380

gaaggcacau ucuuuaccua cgaaagagag gcucaagaau cuacuuauac ucucgaagaa     1440

cuuuuuaggc augaauauac acacuaucuc caagguagau augccguacc aggacaaugg     1500

gguagaacaa aacuauacga uaaugacaga cuuacuuggu augaagaagg aggcgcagaa     1560

cuauuugcgg gcagcacacg uacuucaggc auccuaccac gaaaauccau aguuuccaac     1620

auccacaaua caacaagaaa caaccgauau aaauuaucag auacugucca cucaaaauac     1680

ggugcguccu ucgaauuuua caacuacgca uguauguuua uggacuacau guauaauaaa     1740

gauaugggua uacuuaacaa auugaaugac uuagccaaaa auaaugaugu agacggauac     1800

gauaacuaca uaagagaccu aucaucaaac uaugcauuaa augacaaaua ucaagaccau     1860

augcaagaaa gaauugauaa cuacgaaaac uuaacuguac cauucguagc agaugauuac     1920

uuaguaagac augcauauaa aaauccaaac gaaaucuaca gcgaaaucag cgaaguagcc     1980

aaacucaaag augccaaauc cgaagugaag aaaucacaau acuucucaac auucacuuua     2040

agagguaguu acacaggagg ugcauccaaa ggaaaauuag aagaccaaaa agccaugaau     2100

aaauuuauag acgacagucu aaagaaauua gauaccuacu cauggagugg auacaaaaca     2160

uuaacagccu acuucacaaa cuacaaagua gauucaucua accgagucac cuacgacgua     2220

guauuucaug gcuacuuacc aaacgaaggc gauagcaaaa acucacuacc guacggcaaa     2280

auuaacggca cauacaaagg aacagaaaaa gagaaaauca aauucuccuc cgaagguagc     2340

uucgacccag acgguaaaau cguaaguuau gaaugggauu ucggugacgg caacaaaucg     2400

aacgaagaaa acccagaaca cagcuaugau aaaguaggua cauauacagu caaacuaaaa     2460

guaaccgaug auaaagguga aucgucuguc ucaacgacca cagccgaaau aaaagauuug     2520

uccgaaaaua aauuaccagu caucuauaug caugucccaa aaucaggagc ccuaaaccaa     2580

aaagugguuu ucuauggaaa aggaacauac gacccugaug gaucaauagc aggcuaucaa     2640

ugggauuucg gugacggcuc agacuuuagc agugaacaaa auccaucgca uguguacaca     2700

aagaaaggag aauacacagu aacacuacga gucauggauu cuuccggaca aaugagugag     2760

aaaacgauga aaauuaaaau aacagaccca guauacccaa uaggaacaga aaaagaacca     2820

aauaacucca aagaaaccgc aucuggacca auaguccccg gaauaccagu aagcggcacu     2880

aucgaaaaua caucagacca agacuauuuu uacuuugacg uaauaacccc aggagaagua     2940

aaaauagaca uaaauaaauu aggauacggc ggcgcuacau ggguaguuua cgacgaaaac     3000

aacaaugcag uaucauacgc aacagaugac ggacaaaacu uaaguggaaa auuuaaagcu     3060

gacaaaccag gaagauauua cauacauuua uauauguuca auggauccua uaugccauac     3120

agaaucaaca uagaaggaag cguaggaagg uaaggacuag uuauaagacu gacuagcccg     3180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     3300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          3355


<210>  2504
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt13)

<400>  2504
gggagaaagc uuaccauggg aacauggaua uuauucgcau gccuacuagg agcagcauuc       60

gcaaugccac uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua      120

cuaacaccac uaaaauggua ccaaucaaua cgacccccau acccaucaua cggauaugaa      180

cccaugggag gauggcuaca ccaccaaaua auaccaguac uaucacaaca acauccccca      240

acacacacau uacaaccuca ccaccacaua ccaguaguac cagcacaaca accaguaaua      300

ccacaacaac caaugaugcc aguaccagga caacacucaa ugacaccaau acaacaccac      360

caaccaaacc uaccaccacc agcccaacaa ccauaccaac cacaaccagu acaaccacaa      420

ccacaccaac caaugcaacc acaaccacca guacacccaa ugcaaccacu accaccacaa      480

ccaccacuac caccaauguu cccaaugcaa ccacuaccac caaugcuacc agaccuaaca      540

cucgaagcau ggccaucaac cgauaaaaca aaaagagaag aaguagacua aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  2505
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt13)

<400>  2505
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc auacccauca      120

uacggauacg aaccaauggg aggaugguaa ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  2506
<211>  385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt13)

<400>  2506
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc accaaugcua      120

ccagaccuaa cacuagaagc auggccauca acagacaaaa caaaaagaga agaaguagac      180

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      240

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      360

ggcucuuuuc agagccacca gaauu                                            385


<210>  2507
<211>  424
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt13)

<400>  2507
gggagaaagc uuaccauggc aguaauggca ccaagaacac uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uacauaaacu ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca      180

ccauacccau cauacggaua cgaaccaaug ggaggauggu aaggacuagu uauaagacug      240

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      420

aauu                                                                   424


<210>  2508
<211>  457
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt13)

<400>  2508
gggagaaagc uuaccauggc aguaauggca ccaagaacac uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uacauaaacu ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca      180

ccaccaaugc uaccagaccu aacacuagaa gcauggccau caacagacaa aacaaaaaga      240

gaagaaguag acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      300

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      420

ccccccccca aaggcucuuu ucagagccac cagaauu                               457


<210>  2509
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt13)

<400>  2509
gggagaaagc uuaccauggg aacauggaua cuauucgcau gccuaguagg agccgcauuc       60

gcaaugccac uaccaccaca uccaggacac ccaggauaua uaaacuucuc auacgaagua      120

uuaacaccac ucaaauggua ccaauccaug auaagacccc cauacucauc auacggauac      180

gaaccaaugg gcggauggcu acaccaccaa auaaucccag uaguauccca acaacaccca      240

cuaacacaca cauuacaauc acaccaccac auaccaguag uaccagcaca acaaccaaga      300

guaagacaac aagcauuaau gccaguacca ggacaacaau caaugacacc aacacaacac      360

caccaaccaa accuaccacu accagcacaa caacccuucc aaccucaacc aguacaacca      420

caaccacacc aaccaaugca accacaacca ccaguacaac caaugcaacc acuauuacca      480

caaccaccac uaccacccau guucccacua agaccauuac caccaauacu accagaccua      540

caccuagaag ccuggccagc aacagacaaa acaaaacaag aagaagucga cuaaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  2510
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt13)

<400>  2510
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaucaa ugauaagacc accauacuca      120

ucauacggau acgaaccaau gggaggaugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  2511
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt13)

<400>  2511
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaucaa ugauaagacc accaccaaua      120

cuaccagacc uacaccuaga agcauggcca gcaacagaca aaacaaaaca agaagaagua      180

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  2512
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt13)

<400>  2512
gggagaaagc uuaccauggc aguaauggca ccaagaacac uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uauauaaauu ucucauacga aguacuaaca ccacuaaaau gguaucaauc aaugauaaga      180

ccaccauacu caucauacgg auacgaacca augggaggau gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  2513
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt13)

<400>  2513
gggagaaagc uuaccauggc aguaauggca ccaagaacau uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uacauaaacu ucucauacga aguacuaaca ccacuaaaau gguaucaauc aaugauaaga      180

ccaccaccaa uacuaccaga ccuacaccua gaagcauggc cagcaacaga caaaacaaaa      240

caagaagaag uagacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  2514
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt13)

<400>  2514
gggagaaagc uuaccauggg aacauggaua cuauucgcau gccuacuagg agcagcauuc       60

ucaaugccac uaccaccaca cccaggacau ccaggauaca uaaacuucuc auacgaagua      120

cucacaccau uaaaauggua ccaaaacaug auaagacacc cauacacauc auacggauac      180

gaaccaaugg gcggauggcu acaccaccaa auaauaccag uaguaucaca acaaacccca      240

caaucacacg cauuacaacc acaccaccau auaccaaugg uaccagcaca acaaccagga      300

auaccacaac aaccaaugau gccacuacca ggacaacacu caaugacacc aacccaacac      360

caccaaccaa accuaccccu acccgcacaa caaccauucc aaccacaacc aguacaaccc      420

caaccacacc aacccuuaca accacaauca ccaaugcacc caauacaacc acuacuccca      480

caaccaccac uaccaccaau guucucaaug caaucacuac uaccagaccu accauuagaa      540

gcauggccag caacagacaa aacaaaaaga gaagaaguag acuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  2515
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt13)

<400>  2515
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaaaua ugauaagaca cccauacaca      120

ucauacggau acgaaccaau gggaggaugg uaaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  2516
<211>  388
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt13)

<400>  2516
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaaaca ugauaagaca cccaucacua      120

cuaccagacc uaccauuaga agcauggcca gcaacagaca aaacaaaaag agaagaagua      180

gacuaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc      240

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc      360

aaaggcucuu uucagagcca ccagaauu                                         388


<210>  2517
<211>  427
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt13)

<400>  2517
gggagaaagc uuaccauggc aguaauggca ccaagaacau uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacauccagg acacccagga      120

uauauaaauu ucucauacga aguauuaaca ccacuaaaau gguaucaaaa uaugauaaga      180

cauccauaua caucauacgg auacgaacca augggaggau gguaaggacu aguuauaaga      240

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      420

cagaauu                                                                427


<210>  2518
<211>  460
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt13)

<400>  2518
gggagaaagc uuaccauggc aguaauggca ccaagaacau uaguacuacu acuaucagga       60

gcacuagcac uaacacaaac augggcaaug ccacuaccac cacacccagg acacccagga      120

uacauaaacu ucucauacga aguacuaaca ccacuaaaau gguaccaaaa caugauaaga      180

cacccaucac uacuaccaga ccuaccacua gaagcauggc cagcaacaga caaaacaaaa      240

agagaagaag uagacuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      300

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      420

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            460


<210>  2519
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt13)

<400>  2519
gggagaaagc uuaccauggg aacauggaua cuauucgcau gccuauuagg agcagcauuc       60

ucaaugccac uaccaccaca cccaggacac ccaggauaua uaaacuucuc auacauaaga      120

cacccauaca caucauacgg auacgaacca augggaggau ggcuacacca ccaaauaauu      180

ccaguaguau cacaacaaac accacaauca cacgcacuac aaccacacca ccacauacca      240

augguaccag cacaacaacc aggaauacca caacaaccaa ugaugccacu acccggacaa      300

cacucaauga cacccacaca acaccaccaa ccaaaccuac cacuaccagc acaacaacca      360

uuccaaccac aaccaguaca accacaacca caccaaccau uacaaccaca aucaccaaug      420

cacccaauac aaccacuacu accacaacca ccacuaccac ccauguucuc aaugcaauca      480

cuacuaccag accuaccacu agaagcaugg ccagcaacag acaaaacaaa aagagaagaa      540

guagacuaag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  2520
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt13)

<400>  2520
gggagaaagc uuaccauggg aacauggaua uucuucgcau gccuauuagg agcaucccua       60

gcaaugccac uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua      120

cucacaccau uaaaauggua ccaaaacaug auaagacacc cauacacauc auacggauac      180

gaaccaaugg gaggcuggcu acaccaccaa auaauaccag uaguaucaca acaaacacca      240

caaucacacg cacuacaacc acaucaccac auaccaaugg uaccagccca acaaccagga      300

auaccacaac aaccaaugau gccacuacca ggacaacacu caaugacacc aacacaacac      360

caccaaccaa accuaccacu accagcacaa caaccauucc aaccacaacc aguacaacca      420

caaccccacc aaccacuaca accacaauca ccaaugcacc caauccaacc acuacuacca      480

caaccaccac uaccaccaau guucucaaug caaucccuac uacccgaccu accacuagaa      540

gccuggccag caacagacaa aacaaaaaga gaagaaguag acuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  2521
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt13)

<400>  2521
gggagaaagc uuaccauggg aacauggaua cuauucgcau gccuacuagg agcagcauuc       60

ucaaugccac uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua      120

cuaacaccac uaaaauggua ucaaaacaug auaagacacc caucacuauu accagaccua      180

ccacuagaag cauggccagc aacagacaaa acaaaaagag aagaaguaga uuaaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  2522
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt13)

<400>  2522
gggagaaagc uuaccauggg aacauggaua cuauucgcau gccuauuagg agcagcauuc       60

ucaaugccac uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagac      120

cuauacuuag aagcaauaag aauagacaga acagcauucg uacuaacacc acuaaaaugg      180

uaccaaaaca ugauaagaca cccauacaca ucauacggcu acgaaccaau gggaggaugg      240

cuacaccacc aaauaauacc agucguaucc caacaaacac cccaaucaca cgcauuacaa      300

ccacaccacc acauaccaau ggucccagca caacaaccag guauacccca acaaccaaug      360

augccacuac caggacaaca cucaaugaca ccaacacaac accaccaacc aaaccuacca      420

cuaccagcac aacaaccauu ccaaccacaa ccaguacaac cacaaccaca ccaaccacua      480

caaccacaau caccaaugca cccaauacaa ccacuacuac cacaaccacc auuaccaccc      540

auguucucaa ugcaaucacu auuacccgac cuuccacuag aagcauggcc agcaacagac      600

aaaacaaaaa gagaagaagu agacuaagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  2523
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt13)

<400>  2523
gggagaaagc uuaccauggg aacauggaua cucuucgcau gccuacuagg cgcagcauuc       60

uccaugccac uaccaccaca cccaggacac cccggauaca uaaacuucuc auacgaagua      120

cucacaccac uaaaauggua ccaaaacaug auaagacacc caacaccaca aucacacgca      180

cuacaaccac accaccacau accaauggua ccugcacaac aaccaggaau accacaacaa      240

ccaaugaugc cacuaccagg ccaacacucc augacaccca cacaacacca ccaaccaaac      300

cuaccacuac cagcccaaca accauuccaa ccacaacccg uacaaccaca accacaccaa      360

ccauuacaac cccaaucacc aaugcaccca auacaaccac uacucccaca accaccacua      420

ccaccaaugu ucucaaugca aucacuacua ccagaccuac cacuagaagc auggccagca      480

acagacaaaa caaaaagaga agaaguagac uaaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  2524
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt13)

<400>  2524
gggagaaagc uuaccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc       60

ucauacgaag uacuaacacc acuaaaaugg uaccaaaaca ugauaagaca ccccuacaca      120

ucauacggau acgaaccaau gggaggaugg cuacaccacc aaauaauacc aguaguauca      180

caacaaacac cacaaucaca cgcacuacaa ccacaccacc acauaccaau gguaccagcc      240

caacaaccag gcauaccaca acaaccaaug augccacuac caggacaaca cucaaugaca      300

ccaacacaac accaccaacc aaaccuacca cuaccagcac aacaaccauu ccaaccacaa      360

ccaguacaac cacaaccaca ccaaccacuc caaccacaau cacccaugca ccccauacaa      420

ccauuacuac cacaaccacc acucccacca auguucucca ugcaaucacu acuaccagac      480

cuaccacuag aagcauggcc agcaacagac aaaacaaaaa gagaagaagu agacuaagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  2525
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt13)

<400>  2525
gggagaaagc uuaccaugcc agguguagca cgucuaccau uauugcuagg uuuauugcua       60

cuaccccgac cgggacgacc acuagacuua gccgauuaca cauaugaccu agcagaagag      120

gacgauagug aaccauuaaa cuacaaagau ccauguaaag cugccgcauu cuuaggugau      180

auagcuuuag acgaagaaga uuuacgugca uuucaagucc agcaagcagu agauuuacgu      240

agacauacug cacgcaaaag uucaauaaaa gcagcuguac caggaaacac aucaacaccu      300

uccugucaau caacaaaugg ucaaccucaa agaggggcuu gcggacguug gagggggaga      360

aguagaagua gacgugcagc aacaagucga ccagaacgag uauggccaga uggaguaauu      420

ccauuuguaa uugguggaaa cuuuacugga ucacaaagag cuguauucag gcaagcuaug      480

agacauuggg aaaaacauac uugcguuaca uucuuagaac gaacagauga agauuccuau      540

auaguauuua cuuauagacc uugugggugc uguaguuaug uggguagaag agggggugga      600

ccacaagcaa uaucaauugg uaaaaauugu gacaaauuug gaauaguugu acaugaacua      660

ggacauguag uaggauuuug gcacgaacau acaagaccag auagagacag acauguaucc      720

auaguuagag aaaauauaca accaggacaa gaauauaauu uccuaaaaau ggagccacag      780

gaaguagaga guuugggaga aacuuacgac uucgacagua uaaugcauua ugcaagaaau      840

acuuuuucac gaggaauauu ccuagauacu auugugccua aauacgaagu gaauggugua      900

aaaccuccaa uuggucaaag gacuagguua agcaaaggag auauagcaca agcgcgcaaa      960

cuuuauaaau guccagcaug uggugaaaca uuacaggacu caacaggaaa uuuuucauca     1020

ccugaauacc cuaacgggua uagugcacau augcacugug uauggagaau aucaguaaca     1080

ccaggagaga aaauaauauu aaacuucacu agccuggauc uuuauagauc gagacucugu     1140

ugguaugauu auguagaagu uagagauggc uucuggagaa aagcaccauu gagagggcgu     1200

uuuuguggca guaaacuacc agaaccaaua guaucuacag auuccagauu augggucgag     1260

uucagaaguu cauccaauug gguaggaaaa gguuucuucg ccguauauga agcgauaugc     1320

ggaggggaug uaaagaaaga cuauggucau auacaaagcc cuaauuaucc ugaugacuau     1380

aggccaagua aaguuuguau uuggagaaua caagugucag aagguuuuca cguuggacuc     1440

acauuucaau cuuuugaaau agagcgccau gacucaugug cguaugacua uuuagaggua     1500

agagacggac auucagaauc uucuacucuu auaggaagau auuguggaua ugagaaacca     1560

gaugauauaa aaaguacaag uucucgacua ugguuaaaau uuguaagcga uggaagcaua     1620

aauaaagcag gauuugcagu aaauuucuuu aaagaaguug augaaugcuc gagaccuaau     1680

agagggggau gcgaacaacg augucuaaau acacucggaa gcuacaaaug uagcugugau     1740

ccaggauaug aacuugcacc ggacaaaaga agaugugaag cugcaugcgg cggauuucua     1800

accaaacuca auggaucaau uacuucccca ggauggccua aagaauaucc accgaauaaa     1860

aacugcauau ggcaauuagu agcuccaaca caauaucgca ucagcuuaca auuugacuuc     1920

uuugaaacug agggaaauga uguuuguaaa uaugacuuug ucgaagucag aucaggccuc     1980

acagcagauu cuaaauuaca cggcaaauuu uguggaagcg aaaaaccgga aguaauaaca     2040

ucacaauaca auaacaugag aguagaguuu aaaagcgaua auacaguaag uaagaaagga     2100

uuuaaagcac acuucuucuc agauaaagac gaauguucaa aagacaaugg gggaugucaa     2160

caagacugug uaaauacguu uggaucauau gaaugucaau gccgaagugg auucguacuu     2220

caugauaaua aacaugauug uaaagaagca gguugcgauc acaaaguuac aucaacuuca     2280

ggcacaauaa cuucaccuaa cuggccagau aaauauccau caaagaaaga auguacaugg     2340

gcaauaucuu caaccccagg ucaucgcgua aaauuaacau uuauggaaau ggauauugaa     2400

ucacaaccag aaugugcaua ugaucacuua gaaguauucg acggaaggga ugcaaaagca     2460

ccaguauuag guagauuuug uggcaguaag aaaccagaac caguucuugc gacaggaagc     2520

cguauguuuu uaagauuuua cucagauaau uccguacaaa gaaaaggauu ucaagccucc     2580

caugcgacgg aauguggagg acaaguacga gcagauguua aaaccaaaga ccuauacuca     2640

cacgcacaau uuggugauaa uaauuaccca ggugggguag acugcgaaug gguaauagua     2700

gcagaagaag gguacggagu ugaauuagua uuccaaacau uugaaguaga agaagaaacc     2760

gauuguggcu augauuauau ggaacuauuc gacggauacg acuccacagc accgagauua     2820

ggacgauacu guggaagugg accaccagaa gaaguuuauu cagcaggaga cucagucuua     2880

gugaaauuuc auucggacga cacaauaacc aagaaaggau uccacuuaag auacacuuca     2940

acuaaauucc aagauacacu acacaguaga aaauaaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  2526
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt13)

<400>  2526
gggagaaagc uuaccauggu cgccggaacc agaugccuau uagcccuacu auuaccacaa       60

guucuacuag guggagcugc aggauuagua ccagaacuag gaagacgaaa auucgcggca      120

gcauccucag gaagaccauc aucacagcca ucagacgaag uacuauccga auucgaacua      180

agguuauuau cuauguuugg auuaaaacaa agaccaacgc caucuagaga cgcagucguu      240

ccaccauaca ugcuagaucu auauagaaga cacuccggac aaccaggauc cccagcaccc      300

gaucauagau uagaacgagc cgcaucacgu gcaaacaccg uaagauccuu ccaccacgaa      360

gaaucucuag aagaacuacc agaaacauca ggaaaaacua caagaagauu cuucuuuaac      420

cuaucaucua ucccaacaga agaauucauc acaucagcag aauuacaagu cuuuagagaa      480

caaaugcaag acgcauuagg aaauaacuca ucauuucacc acagaauuaa cauauacgaa      540

auaaucaaac cagcaaccgc aaacagcaaa uucccaguca cucgauuacu agauacaaga      600

cuaguuaacc aaaacgcauc aagaugggaa ucauuugacg uaacucccgc aguuaugaga      660

uggacagcac aaggacacgc aaaucacgga uuugucguug aaguagccca uuuagaagaa      720

aaacaaggag uuucaaaaag acacguccgc auaagcagau cacuacauca agacgaacau      780

ucuuggaguc aaauaagacc acuacuugua acauucggcc acgacggaaa aggacaccca      840

uuacacaaaa gagaaaaaag acaagcaaaa cacaaacaaa gaaaaagacu aaaaucauca      900

ugcaaaagac auccauuaua cguagauuuc ucagauguag gauggaacga cuggauagua      960

gcaccaccag gauaccacgc auuuuacugc cauggagaau gcccauuucc acuagcagac     1020

caccucaacu caaccaacca cgcaauaguu caaacccuag uaaauucagu aaauucaaaa     1080

auaccaaaag caugcugugu cccaacagaa cuuucugcaa uaucaaugcu auauuuagau     1140

gaaaacgaaa aaguaguucu aaaaaauuac caagacaugg ucguagaagg augcggaugu     1200

agauaaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  2527
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt13)

<400>  2527
gggagaaagc uuaccaugau accaggaaau agaaugcuca ugguaguauu auuaugccaa       60

guacuucuag guggagcuuc acaugcauca cuuauaccag aaaccggaaa aaaaaaagua      120

gcagaaauac aaggacaugc cggaggaaga agauccggac aaucacauga auuacuacga      180

gauuuugagg ccacuuuauu acagauguuc ggauuaagaa gacgaccuca accaucaaaa      240

ucagcaguaa uuccagacua caugcgagau cuauacagau uacaaucagg agaagaagaa      300

gaagaacaaa uacacaguac cggacuagaa uacccagaaa gaccagcauc aagagccaau      360

accguuagau cauuccacca ugaagaacau uuagaaaaua uaccaggaac aucagaaaau      420

ucagcuuuca gauuuuuauu caauuuaagc agcauaccag aaaacgaagu cauaucauca      480

gcagaacuaa gacuauuuag agaacaaguu gaccaaggac cugacuggga acgcggauuc      540

cacagaauaa auauauacga aguaaugaaa ccaccugcug aaguaguacc aggacaccua      600

auaacuagau uacuagauac aagacuagua caccauaaug uaacaaggug ggaaacauuu      660

gacguaucac cggcaguauu acgguggaca agagaaaaac aaccaaauua cggacuagca      720

auagaaguca cacacuuaca ucaaacaaga acacaucagg gucaacacgu aagaauauca      780

cgaucacuuc cacaagguuc agguaacugg gcccaauuaa gaccauuacu aguaacauuu      840

ggacaugacg gaagaggaca cgccuuaaca cgaaggcgaa gagccaaaag aaguccaaaa      900

caccauucac aaagagcacg aaaaaaaaac aaaaauugcc gaagacauuc acuauacgua      960

gacuuuucag augucggaug gaaugacugg aucguagcac caccaggcua ccaagcauuu     1020

uacugucacg gagauugccc auuuccacua gcagaucacu uaaacucaac caaucacgca     1080

auaguacaaa cacuaguaaa uucuguaaac agcucuauac caaaagcuug uuguguacca     1140

acagaacuau cagccauauc uauguuauau cuagaugaau augauaaagu aguauuaaaa     1200

aacuaucaag aaauggucgu agaaggaugc ggauguagau aaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  2528
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt13)

<400>  2528
gggagaaagc uuaccaugcc cggauuagga agacgagcac aauggcuaug cugguggugg       60

gguuuauuau guagcuguug cgguccacca ccuuuaagac caccauuacc agccgcagcu      120

gcugcugcag caggcgguca acuauuagga gaugggggau cacccgggag aacagaacaa      180

cccccaccau caccccaaag cucaucaggg uucuuauaca gaagauuaaa aacacaagaa      240

aaacgcgaaa ugcaaaaaga aauacuaagu guauuaggau ugccacauag accuagacca      300

uuacauggau uacaacaacc acaaccucca gcuuuaagac aacaagaaga acaacaacaa      360

caacaacaau uacccagagg agaaccaccc ccaggaagac uaaaaucugc uccauuauuc      420

augcuagacc uauacaaugc acuaagcgca gacaaugacg aagauggagc uucugaagga      480

gaaagacaac aaucauggcc ucaugaagca gcuucaagca gucaaaggag acaaccacca      540

ccaggagcag cacacccacu uaaucgaaaa agccuacuag cacccggcuc uggaucagga      600

ggcgcaaguc cauuaacauc agcacaagau agcgcguuuu uaaaugacgc agacauggua      660

augucauucg ugaauuuagu agaauacgau aaagaauuuu cuccaagaca aagacaccac      720

aaagaguuca aauucaaucu aucccaaaua ccugaaggag aaguaguaac ugcagcagaa      780

uuuagaaucu acaaagacug uguaauggga ucauucaaaa aucaaacuuu cuuaauaucu      840

aucuaccaag uauuacaaga acaucaacau agagacucug auuuauuccu cuuagacaca      900

agaguuguau gggcaucaga agaagguugg cuagaauuug acauuacugc aacaucaaac      960

uuauggguag uaacaccaca acauaacaug ggacuacaau uaucagucgu aaccagagau     1020

gguguucaug uacacccuag agcugcagga cuuguaggca gagacggacc auacgauaaa     1080

caaccauuca ugguagcauu cuucaaagua ucagaaguac auguaagaac aacacgaucu     1140

gcuagcucaa gaagaagaca acaaagucgc aacagaucua cacaaucaca agauguagca     1200

cgaguaucau cugcuucaga cuauaacucc uccgaacuaa aaacagcaug caggaaacac     1260

gaauuauacg uuuccuucca agauuuagga uggcaagacu ggauaauagc acccaaagga     1320

uacgcugcaa acuacugcga cggugaaugu ucauuuccau uaaaugcaca uaugaacgca     1380

acaaaccaug caaucguaca aacucuagua caccuaauga auccagaaua uguccccaaa     1440

ccauguugcg cacccacaaa acuuaacgca auaucagucu uauacuuuga cgacaauuca     1500

aauguaaucc uaaagaaaua uagaaacaug guagucagag ccugcgguug ccauuaagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  2529
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt13)

<400>  2529
gggagaaagc uuaccaugca uguaagauca cuaagagcag cugccccaca cucauuugua       60

gcacuguggg caccacuuuu uuuacuaaga agcgcauuag cagacuuuuc acuagacaau      120

gaaguacauu caagcuuuau ucauaggaga cuucggucac aagaaagacg ugaaaugcaa      180

agagaaauau uaucuauucu aggacuacca caccgcccaa gaccacaucu acaaggaaaa      240

cacaauucag cuccaauguu caugcuagau cuuuauaacg caauggcagu cgaagaagga      300

ggaggccccg gaggacaagg auuuuccuau ccauauaaag caguauuuuc aacacaagga      360

ccuccucuag caagucuaca agauucacau uucuuaacag augcagauau gguaauguca      420

uuuguaaauu uaguagaaca ugauaaagaa uuuuuucacc cacguuacca ccauagagaa      480

uucagauucg aucuaucuaa aauaccagaa ggugaagcag uaacagcagc ugaauucaga      540

auauacaaag auuacauacg agaaagauuu gacaacgaaa cauucagaau aucaguauau      600

caaguacuac aagaacacuu agguagagaa agcgaucuau uucuauuaga cuccagaaca      660

cucugggcau cagaagaagg cuggcuagua uucgauauaa cagcaaccag uaaucacugg      720

gucguaaacc caagacacaa ccucggacua caauuaucag uagaaacauu agacggccaa      780

aguauuaacc caaaacucgc aggacuaaua ggaagacacg gaccacaaaa caaacaacca      840

uucaugguag cauucuuuaa agcaaccgaa guacacuuca gaucaauacg aucaacagga      900

uccaaacaaa gaagccaaaa uagaucaaaa acuccaaaaa aucaagaagc auuaagaaug      960

gcaaauguag cugaaaauuc aucaagugau caaagacaag ccugcaaaaa acacgaauua     1020

uacguauccu uccgagauuu aggauggcaa gacuggauaa uagcaccuga aggcuacgcc     1080

gcauacuacu gugaaggaga augugcauuu cccuuaaacu cauauaugaa cgcaacuaau     1140

cacgcuauag uacaaacacu aguacacuuu auaaaucccg aaacaguacc caaaccaugc     1200

ugcgcaccaa cacaacucaa cgcuauauca guauuauauu uugacgacuc uucuaacguu     1260

auccuaaaaa aauaucgaaa uaugguaguc agagcaugug gcugccacug aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  2530
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt13)

<400>  2530
gggagaaagc uuaccaugaa agcaucagca gcacuacuau gccuacuacu aacagcagca       60

gcauucucac cacaaggacu agcacaacca guaggaauaa acacaucaac aacaugcugc      120

uacagauuca uaaacaaaaa aauaccaaaa caaagacuag aaucauacag aagaacaaca      180

ucaucacacu gcccaagaga agcaguaaua uucaaaacaa aacuagacaa agaaauaugc      240

gcagacccaa cacaaaaaug gguacaagac uucaugaaac accuagacaa aaaaacacaa      300

acaccaaaac uauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  2531
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt13)

<400>  2531
gggagaaagc uuaccauguu gcuuacuuua auaauauuac uuccaguugu caguaaauuu       60

ucguuugugu cauuaucugc accacaacau uggaguuguc cagaagguac gcuagcaggc      120

aacgguaauu cuacgugugu cgguccagcg ccauuucuaa ucuuuucuca ugguaacucc      180

auuuuuagaa uagauacaga agguacaaau uacgaacaau uaguaguuga cgcaggaguc      240

agcguaauaa uggacuuuca uuauaaugag aaaagaaucu auuggguaga cuuggaaaga      300

caauuacuuc agcguguauu cuugaaugga uccagacaag aaagaguaug uaauauagag      360

aaaaauguau cagguauggc uauaaacugg auaaaugaag aagugauuug gucaaaucaa      420

caagaaggga ucauuaccgu uacagacaug aaaggaaaua auucccacau acuacuauca      480

gcacuaaaau aucccgccaa uguugcagua gauccagugg aaagauuuau auuuuggucc      540

ucagaaguag caggaucauu auauagagca gacuuagacg gugugggugu uaaggcuuua      600

cuagaaacuu cugagaaaau uaccgcagua aguuuagacg uuuuagacaa aagauuauuu      660

uggauucaau auaauaggga agguucaaau ucacuuauau guucuugcga cuaugauggu      720

ggaucagugc auauaaguaa acauccaacg caacacaauc ucuuugcaau gucuuuauuu      780

ggugauagaa uauuuuacag cacuuggaaa augaaaacaa uauggauagc caacaaacau      840

accggaaaag auaugguaag gauaaaucua cacaguuccu ucguuccuuu aggugaacua      900

aaaguaguac auccacuagc gcaaccuaaa gcggaagaug acacuuggga accagaacaa      960

aaacuaugua aguuacgaaa aggcaacugu ucaucuacag ugugcgggca agacuuacaa     1020

agucacuuau guaugugcgc ggaaggcuau gcgcucagua gagauagaaa auauugugaa     1080

gauguaaaug aaugugcauu uuggaaccau ggauguacac uaggaugcaa aaauacacca     1140

gguucauauu auuguacuug ucccguugga uuuguccugu uaccagacgg caaaaggugc     1200

caucagcuag uaaguugucc acguaauguu ucagaaugua gccacgauug uguuuugaca     1260

agugaaggac cacuaugcuu uugcccagaa ggaucaguau uagaaaggga uggaaaaaca     1320

uguagugguu guaguucacc agauaaugga gguuguaguc aacuuugugu uccauuaucu     1380

ccuguaucuu gggaaugcga uuguuuccca gguuaugauu uacaauuaga ugagaaaagu     1440

ugugcagcgu cuggcccaca accauucuua cucuuugcaa auucacaaga uauaagacac     1500

augcauuucg auggcaccga cuacggcacc cuauuaaguc aacaaauggg gaugguauau     1560

gcacuugacc augauccagu agaaaacaaa auauacuucg cacauaccgc acucaaaugg     1620

aucgaaagag caaauaugga cggaagucaa agggaacggu ugauugaaga aggaguagau     1680

guaccugagg guuuagcagu ugauuggaua gggaggagau uuuauuggac ggacaggggg     1740

aaaaguuuaa uaggacgaag cgaccucaac gggaaaagaa gcaaaauaau cacuaaagaa     1800

aauauuucac aaccaagagg aauugcugua cauccaaugg caaaacgucu auuuuggaca     1860

gacacaggaa uaaauccuag aauagagucc aguucacugc aaggauuggg gagauuagug     1920

aucgccaguu ccgaccuaau auggccaucg ggaauuacaa uagacuuuuu aaccgauaaa     1980

cuauauuggu gcgaugcaaa acagucagua auugaaaugg ccaaucuaga uggaucuaaa     2040

agaagaagac uaacacaaaa ugauguggga cacccauuug cuguugccgu uuucgaggac     2100

uacgucuggu uuucagauug ggcaaugcca agugucauga gagucaauaa gagaacuggu     2160

aaggauagag ucagauuaca aggcucaaug uuaaaaccau cgagucuagu cguaguccac     2220

ccauuagcaa aaccaggugc agaucccugc uuauaucaaa auggagggug cgaacacaua     2280

uguaagaaaa gacuuggcac agcauggugu ucauguagag aaggauuuau gaaggcuuca     2340

gauggaaaaa ccuguuuagc auuagauggc caucaacuuc ucgccggagg agaaguugac     2400

uugaaaaacc aaguaacacc ccuagauaua uuaagcaaaa caagaguuag cgaagauaac     2460

auaacagaau cucaacauau guuaguagca gaaauuaugg ucucagauca agaugacugc     2520

gcaccuguag gauguucuau guaugcuaga ugcauaucag agggggaaga ugcgacaugu     2580

caaugcuuaa aaggauuugc aggcgacgga aaauuaugcu cagacauaga cgaaugugaa     2640

augggaguuc cuguuugucc uccagcaucu uccaaaugua uaaauaccga aggugguuau     2700

guauguagau guagugaagg auaccaaggg gacgguaucc auuguuuaga uauagaugaa     2760

ugccaauugg gagaacacuc cuguggagag aacgcauccu guacaaauac ugaaggaggu     2820

uauacgugua ugugcgcagg aaggcuuucc gaaccugguu uaauuugccc agauucaaca     2880

ccucccccac accuucguga agaugaccac cauuauagug uacgaaauuc agauucugag     2940

ugcccacuaa gccaugaugg auauuguuua cacgauggag uaugcaugua cauagaagcg     3000

uuggauaaau acgcuuguaa uugugugguu ggauacauag gugaaagaug ucaauaccga     3060

gaccuaaaau ggugggaacu aagacaugcc gggcacggac aacaacaaaa aguaauaguc     3120

guugcagugu guguaguagu cuuagucaug cuauuacuau ugagccucug gggugcacac     3180

uauuauagga cacaaaaacu acuaucuaaa aaccccaaaa auccauauga agaaucaagu     3240

cgugauguca gaucaagaag accagcagac acagaagacg gaaugucauc guguccacaa     3300

ccaugguuug ugguaauuaa agaacaucaa gaucucaaaa acggaggcca acccguugcu     3360

ggugaagaug gacaagcagc agaugguagu augcagccca caucauggcg acaagagcca     3420

caauuaugcg gcaugggaac agaacaaggu uguuggauuc caguuaguuc ugacaaagga     3480

agcuguccgc aagugaugga gaggucauuu cauaugccaa gcuacggaac acagacacuc     3540

gaaggcggag uagagaaacc acauucgcuu cuuucugcaa acccauuaug gcaacaaaga     3600

gcucuagauc caccucacca aauggaauug acucaauaag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  2532
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt13)

<400>  2532
gggagaaagc uuaccaugac agcaggcaga agaauggaaa ugcuaugugc aggacgagua       60

ccagcauuau uacuaugucu aggauuccau uuauuacaag caguacuaag cacaacagua      120

auaccaagcu guauaccagg agaaagcuca gacaauugca cagccuuagu acaaacagaa      180

gacaauccaa gaguagcaca aguaaguaua acaaaaugcu caagcgauau gaauggauau      240

ugcuuacacg gacaauguau auaucuagua gacaugagcc aaaacuauug cagaugcgaa      300

gucggauaca caggaguaag augugaacau uucuucuuaa caguacauca accacuauca      360

aaagaauacg uagcauuaac aguaauauua auaauacuau uucuaauaac aguaguagga      420

agcacauacu auuucuguag augguacaga aacagaaaau cgaaagaacc aaaaaaagaa      480

uacgaacgag uaacaucagg agauccagaa cuaccacaag uauaaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  2533
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt13)

<400>  2533
gggagaaagc uuaccauggc agaaggagaa auaacaacau ucacagcacu aacagaaaaa       60

uucaaccuac caccaggaaa cuacaaaaaa ccaaaacuac uauacugcuc aaacggagga      120

cacuuccuaa gaauacuacc agacggcaca guagacggaa caagagacag auccgaccaa      180

cacauacaac uacaacuauc agcagaauca guaggagaag uauacauaaa aucaacagaa      240

acaggacaau accuagcaau ggacacagac ggacuacuau acggaucaca aacaccaaac      300

gaagaaugcc uauuccuaga aagacuagaa gaaaaccacu acaacacaua cauaucaaaa      360

aaacacgcag aaaaaaacug guucguagga cuaaaaaaaa acggaagcug caaaagagga      420

ccaagaacac acuacggaca aaaagccaua cuauuccuac cacuaccagu aucaucagac      480

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  2534
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt13)

<400>  2534
gggagaaagc uuaccauggu aggaguagga gggggagaug uagaagaugu aacaccaaga       60

ccagguggau gucaaauuag cggaagaggu gcaagaggau guaauggaau accaggagca      120

gcagcuuggg aagcagcauu accgagaaga cgaccgagaa gacauccgag ugugaaucca      180

agaucaagag cagcuggaag cccaagaaca agaggaagaa gaacagaaga aagaccaagu      240

ggaagcagau uaggagauag aggaagagga cgagcauuac caggaggaag auuaggagga      300

agaggaagag gaagagcacc agagagagua ggagggagag gaagaggaag aggaacagca      360

gcgccaagag cagcaccagc agcaagagga ucaagaccag gaccagcagg aacaauggca      420

gcgggaagua uaacaacauu accagcucua ccagaagaug gaggaagugg ggcguuucca      480

ccaggacauu uuaaagaucc aaaaagauua uauuguaaaa auggaggauu uuuuuuaaga      540

auacauccag auggaagagu agauggggua agagaaaaau cagauccaca uauaaaauua      600

caauuacaag cggaagaaag aggaguggua aguauuaaag gaguuugugc aaauagauau      660

uuggcgauga aagaagaugg gagguuauua gcaaguaaau guguaacgga ugaauguuuu      720

uuuuuugaaa gacuagaaag caauaacuau aacacauaua gaucgagaaa auacacauca      780

ugguauguag cauuaaaaag aacaggacaa uauaaacuag gaaguaaaac aggaccagga      840

caaaaagcaa uauuauuuuu accaaugagu gcaaagaguu aaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  2535
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt13)

<400>  2535
gggagaaagc uuaccaugca caaauggaua cuaacaugga uacuaccaac acuacuauac       60

agaagcugcu uccacauaau augccuagua ggaacaauau cacuagcaug caacgacaug      120

acaccagaac aaauggcaac aaacguaaac ugcucaucuc cagaaagaca cacaagauca      180

uacgacuaca uggaaggagg agacauaaga guaagaagac uauucugcag aacacaaugg      240

uaccuaagaa uagacaaaag aggaaaagua aaaggaacac aagaaaugaa aaacaacuac      300

aacauaaugg aaauaagaac aguagcagua ggaauaguag caaucaaagg aguagaauca      360

gaauucuacc uagcaaugaa caaagaaggc aaacuauacg caaaaaaaga augcaacgaa      420

gacugcaacu ucaaagaacu aauacuagaa aaccacuaca acacauaugc aagcgcaaaa      480

uggacacaca acggaggaga aauguucgua gcauuaaacc aaaaaggaau accaguaaga      540

ggaaaaaaaa caaaaaaaga acaaaaaaca gcacacuucc uaccaauggc aauaacauaa      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  2536
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt13)

<400>  2536
gggagaaagc uuaccaugaa auuauuacca ucaguaguac uaaaacuauu ucuagcagca       60

guacuaucag cauuaguaac aggagaaagc cuagaaagac uaagaagagg acuagcagca      120

ggaaccucaa acccagaccc accaacagua ucaacagauc aauuacuacc acuaggcgga      180

ggaagagaua gaaaaguaag agacuuacaa gaagcagacc uagauuuacu aagaguaaca      240

uuaucaucaa aaccacaagc acuagcaaca ccaaacaaag aagaacacgg aaaaagaaaa      300

aaaaaaggaa aaggauuagg aaaaaaacga gauccaugcc uaagaaaaua uaaagacuuc      360

ugcauacaug gagaaugcaa auacgucaaa gaacucagag caccaagcug cauaugucac      420

ccuggauacc acggagaaag augccacgga cuaagucuuc caguagaaaa cagauuauac      480

acauacgacc acacaacaau acuagcagua guagcaguag uauuaagcuc aguaugucua      540

uuaguaauag uaggucuacu aauguucaga uaucaccgaa gaggaggaua cgauguagaa      600

aaugaagaaa aaguaaaacu aggaaugaca aauagccacu aaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  2537
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt13)

<400>  2537
gggagaaagc uuaccaugug gguaacuaaa cuauuaccag cauuacuauu acaacauguc       60

cuacuacacc uacuauuacu accuauugca auaccauacg ccgaagguca aagaaaacga      120

agaaauacaa uacaugaguu caaaaaguca gcaaaaacaa cauuaaucaa aauagaccca      180

gcacuaaaaa uaaaaacaaa gaaaguaaau acagcagauc aaugugcaaa cagaugcacu      240

agaaacaaag gacuaccauu uacauguaaa gcauucguau uugauaaagc aagaaaacaa      300

ugucuauggu uuccauuuaa uagcaugagu ucaggaguaa agaaagaguu cggacaugaa      360

uuugaccuau augaaaauaa agacuauaua agaaauugca uaauagguaa aggaagauca      420

uauaaaggaa caguuuccau cacaaaauca ggaauaaaau gucaacccug gucaucaaug      480

auaccacacg aacauagcuu ucuaccaagc ucauacagag guaaagaucu acaagaaaau      540

uauuguagaa auccgagagg ugaagaaggc ggaccauggu guuuuacuuc uaauccagaa      600

guacgauaug aaguauguga uauaccgcaa ugcucagaag uagaauguau gacauguaac      660

ggagaaucau auagagguuu gauggaucau acagaaucag gcaaaauaug ucaaaggugg      720

gaccaccaaa cuccacaucg acauaaauuu cuaccagaac guuauccaga uaaaggcuuu      780

gaugauaauu acugucgaaa cccagacgga caaccaagac cuuggugcua cacauuagau      840

ccccauacuc gaugggaaua cugugcaaua aaaacaugcg cagauaacac aaugaaugac      900

acagauguuc cucuagaaac uacugaaugc auacaaggac aaggagaagg auaccgagga      960

acuguaaaua caauauggaa uggaauaccu ugucaaagau gggauucaca auauccucau     1020

gaacaugaca ugaccccaga aaauuuuaaa ugcaaagauc uaagagaaaa uuauugcaga     1080

aacccagacg gaucugaauc gccauggugu uuuacaacug auccuaacau aagaguaggc     1140

uauugcucuc agauaccgaa uugcgacaug agccauggac aagacuguua uagaggaaau     1200

ggcaaaaauu acaugggaaa ucucagucaa acaagaucag gauuaacuug uucaaugugg     1260

gacaaaaaua uggaagauuu acauagacac auauucuggg aaccagacgc aucaaaauua     1320

aaugaaaacu auugcagaaa uccagaugac gacgcacacg ggccauggug uuauacagga     1380

aauccauuaa uaccauggga cuacuguccu auaagccgau gugaaggaga uacaacuccc     1440

acaauuguaa acuuagauca uccaguaauc ucaugugcca aaacaaaaca auuaagaguc     1500

guaaacggua uaccuacuag gacaaacaua ggcuggaugg ugucacuuag auauagaaau     1560

aaacacauau gcggaggcag ucuuauaaaa gaaucauggg uccucacagc aagacaaugu     1620

uuucccagca gagauuuaaa ggacuaugaa gcaugguuag gaauacacga uguacacgga     1680

cgaggagacg aaaaauguaa acaaguacua aauguuucuc agcuagucua uggaccagaa     1740

gggagcgauu uagucuuaau gaaacuagca agaccggcag ucuuagacga cuucguaucu     1800

acaauugauu uaccuaacua cggaugcacg auaccagaaa agacuagcug uucuguuuau     1860

ggaugggguu auacuggacu aaucaacuac gacggacuau uaaggguggc acauuuauau     1920

auuaugggaa acgaaaaaug uucucaacac cacagaggaa aaguaacauu aaacgaauca     1980

gaaauaugcg caggagcaga gaaaaucgga ucaggcccgu gugaaggaga cuaugguggg     2040

ccgcuagugu gcgaacaaca caaaaugcga augguauuag ggguaauagu accuggacgg     2100

ggaugcgcca uaccaaauag accaggaaua uucguaagag uagcauauua ugccaaaugg     2160

auacauaaaa uaauacuaac auauaaagua ccacaaucuu aaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  2538
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt13)

<400>  2538
gggagaaagc uuaccauggc caaagcagcu gcaauaggaa uagaucuagg aacaacauac       60

uccuguguag gaguauucca acacggaaaa guagaaauaa ucgcaaauga ucaagguaac      120

agaacaacac caucauacgu ugcauuuaca gacacagaaa gauuaauagg agaugcagcc      180

aaaaaccaag ucgcacuaaa uccacaaaac acaguauuug augcaaaacg cuuaauagga      240

agaaaauuug gcgauccagu aguacaauca gacaugaaac auuggccauu ucagguaaua      300

aacgauggag auaaaccaaa aguucaaguu aguuacaaag gcgaaacuaa agcauuuuac      360

ccggaagaga uaucaagcau gguauuaaca aaaaugaaag aaaucgcaga ggcuuauuua      420

ggauacccag uaacaaacgc aguaauaaca guaccagcuu acuuuaauga uagucagaga      480

caagcaacua aagaugccgg aguaauugcc ggacuaaacg uacuaagaau aauaaacgaa      540

ccaacugcag cagcaauagc auauggauua gauagaacag gcaaaggaga aagaaaugua      600

uuaauauucg accuaggagg agguacauuc gacgugucaa uauuaacaau ugaugaugga      660

auauucgaag uaaaagcaac agccggggac acacauuuag ggggagaaga uuuugacaac      720

agacugguaa accauuuugu agaagaauuu aaaagaaaac acaagaaaga cauuucacaa      780

aauaaaaggg caguuagaag acuaagaacu gcaugugaga gggcaaaaag gacguuaagc      840

aguaguaccc aagcaucacu agagauagac ucauuauuug aaggaauuga uuuuuauacu      900

ucaaucacga gagcgagauu ugaagaauua uguagugauc ucuuuagauc gacauuagaa      960

ccugucgaaa aagcacuaag agaugcgaaa cuagacaaag cacaaauaca ugacuuaguu     1020

cuaguaggag gaucaaccag aauaccaaaa guacaaaaac uacuacaaga uuucuucaac     1080

ggaagggacu uaaauaaauc aauaaaccca gaugaagcug ucgcuuacgg ugcagcuguc     1140

caagcagcaa uacuaauggg agauaaaagc gagaaugugc aagacuuauu auuauuagac     1200

guugcaccuc uaucgcuagg acuagaaaca gcaggaggag uaaugacagc acuuauaaaa     1260

agaaacagca caauaccgac uaaacaaacg caaauauuua caaccuauuc agauaaccaa     1320

ccuggcgucc uuauacaggu uuaugaaggu gaaagagcaa ugacaaaaga uaacaaucua     1380

cuaggaagau uugagcuaag uggaauacca ccagcaccuc gaggaguacc acaaauagaa     1440

guuacauucg acauagacgc uaauggcauu cuaaauguga cagcuacuga caaaaguacc     1500

ggaaaagcaa auaaaauaac uauuacaaac gauaaaggaa gacuaagcaa ggaagagaua     1560

gaacgcaugg uacaggaagc agaaaaauac aaagcggaag acgaggucca gcgagaaaga     1620

guaagcgcua aaaacgcauu agaaucauau gcauucaaca ugaaaagcgc aguagaagau     1680

gaaggacuaa aagguaaaau aagcgaagca gauaaaaaga aaguacuaga uaaaugucaa     1740

gaaguuauaa guugguuaga ugcaaauacu uuagcggaaa aagaugaauu ugaacauaaa     1800

agaaaagaac uagaacaggu augcaauccu auuauaucag gauuauacca aggagcugga     1860

ggaccaggac caggaggcuu cggagcacaa ggaccgaaag gaggauccgg aucagggcca     1920

acaauagaag aaguagauua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2539
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt13)

<400>  2539
gggagaaagc uuaccauggc aaaagcugca gcaauaggaa uagaccuagg aacaacauac       60

uccugcguag gaguauuuca gcaugguaaa guugaaauaa uagcuaacga ccaaggcaac      120

agaacaaccc ccucauacgu cgcauucaca gauaccgaaa gauuaaucgg agaugcggcu      180

aaaaaccaag uggcacucaa uccacaaaac acaguauuug acgcaaaaag acugauagga      240

agaaaauucg gcgauccagu gguucaauca gauaugaaac auuggccauu ccagguaaua      300

aaugauggag auaaaccaaa aguacaagua ucauauaaag gagaaacaaa agcauuuuau      360

ccagaggaaa uaaguaguau gguauuaaca aaaaugaaag aaauagcuga agcauaucuc      420

ggauacccag uaacaaacgc cguaauaaca guuccagcau auuucaacga cagucaaaga      480

caagcaacaa aagaugcagg aguaauagcu ggccuaaaug uacuuagaau aauaaaugaa      540

ccuacugcug cugccauagc auacggacua gaucgaacag gcaaaggaga aagaaauguu      600

uuaauauucg accuuggagg aggaacauuc gacguaagca uuuuaacaau agaugaugga      660

auauuugaag uuaaagccac ugcaggggau acucaccuag gaggagaaga uuucgauaac      720

aggcuaguua aucauuuugu agaagaauuu aaaagaaaac auaagaaaga cauaagucaa      780

aacaaaagag caguaagaag auugagaaca gcaugugaaa gagcuaaaag aacgcuaagc      840

ucaagcacac aagcaaguuu agaaauagau aguuuauuug aaggaauaga uuuuuauacu      900

ucgauaacga gagcaagauu ugaagaauua uguucagauu uauuuagauc aacguuagaa      960

ccaguugaaa aagcacuaag agacgcaaaa uuagauaaag cucaaauaca ugaccuaguc     1020

uuggucggag gcucaacacg aaucccuaaa guacaaaaau uacuucaaga uuucuuuaac     1080

gguagagauc uaaauaaauc aauaaauccc gacgaagcug uagcauaugg agcagcugua     1140

caagccgcaa uucuuauggg agauaaauca gaaaauguac aagauuugcu acuuuuagac     1200

guggcaccac uuagccuagg acuagaaaca gcuggaggag uaaugaccgc auuaauaaaa     1260

cgcaacucga cuauaccaac aaaacaaaca caaaucuuua caacauacag ugauaaucaa     1320

ccaggaguac uaauacaagu auaugaagga gaaagagcaa ugacuaaaga caauaaucua     1380

cuaggacggu ucgaacuaag cggcauucca ccagcaccuc gaggaguacc acaaauugaa     1440

guaacauuug auauagacgc aaacgggaua uuaaacguua cagcaaccga uaaaagcaca     1500

ggcaaagcaa acaaaauaac aauuacaaau gauaaaggaa gacuuucaaa agaagaaaua     1560

gagagaaugg uacaagaagc ugagaaauac aaagccgaag acgaagucca aagagaaaga     1620

guuagcgcua aaaacgcacu ggaaucauau gcuuucaaua ugaaaucagc aguagaggac     1680

gaaggacuaa aaggcaaaau uucagaagca gacaaaaaga aaguacuaga uaaaugucaa     1740

gaaguaauua gcugguuaga ugcaaauacc cuggcagaga aagaugaauu ugaacauaaa     1800

agaaaagaau uagaacaagu augcaauccc auaauaucag gucuguauca aggagcaggc     1860

gggccaggac caggaggauu uggagcacag ggaccaaaag guggauccgg uagcggccca     1920

acaaucgaag aaguagauua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2540
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt13)

<400>  2540
gggagaaagc uuaccauggc aacagcaaaa ggaauagcaa uaggaauaga cuuagggaca       60

acuuacaguu guguuggagu auuucagcac gggaaagucg aaauaauagc aaacgaucaa      120

gguaauagga ccaccccuuc guacguagca uuuacagaua cugaaagacu aauaggugau      180

gcagcgaaaa accaagucgc aaugaacccg caaaauacag uauuugacgc aaaacgguua      240

auuggaagaa aguuuaacga cccaguugua caagcagaua ugaaauuaug gccauuccaa      300

guaauaaacg aaggaggaaa accuaaagug uugguauccu auaaaggcga aaacaaagca      360

uuuuauccgg aagaaauauc aucaauggua cuaacaaaac uuaaagaaac ggcagaagca      420

uuucuaggac auccagucac aaacgcagua auaacaguuc cagcauacuu uaacgauagu      480

caaagacaag caacgaaaga ugcaggaguu auagcagguc uaaauguacu uaggauaauc      540

aacgaaccaa cggcagcagc aauagcauac ggacuagaua aaggaggaca aggagaaaga      600

cauguacuaa uauuugauuu aggcggagga acauucgacg uaaguauauu aaccauagau      660

gauggaauau ucgaaguaaa agcaacagca ggggacacac acuuaggagg cgaagacuuc      720

gauaacaggc uaguaagcca uuuuguagaa gaguucaaaa gaaaacacaa gaaagauaua      780

ucacaaaaua aacgcgcagu acgaagacuc agaacagcuu gcgaaagggc aaaaagaacc      840

uuaagcucua guacacaagc aaaccuggaa aucgauaguu uauacgaagg aauagauuuc      900

uauacaucaa ucacuagagc uagauuugaa gaacucugug cagaucuauu uagaggaaca      960

uuagaacccg uagaaaaagc gcuuagagac gccaaaaugg acaaagcaaa aauacaugac     1020

auaguccuag uagguggaag uacgcguaua ccaaaaguac aaagauuauu acaggauuau     1080

uucaacggaa gagaucuuaa caaaaguaua aaucccgaug aagcaguagc auacggugca     1140

gcaguacagg cagcaauacu aaugggagau aaaucugaaa aaguacaaga cuuacuacug     1200

uuagacguag caccacuuuc acuaggacua gaaacagcug gagguguaau gacagcauua     1260

auaaaaagaa auucaacuau accaacuaaa caaacacaaa uauuuacaac cuauagugac     1320

aaucaaccag gaguacuaau acaaguauau gaaggagaaa gagcaaugac aaaagauaac     1380

aaucugcuag gaagauuuga ucuaacggga auaccaccag caccaagagg aguaccacaa     1440

auagaaguaa cguuugacau ugaugcaaau ggaauacuaa acgugaccgc cacagauaaa     1500

aguacuggaa aagucaauaa aauaacuauc acaaacgaua aagggagacu aagcaaagaa     1560

gagauagaaa gaaugguuuu agaugcagaa aaauacaaag cagaagacga gguacaaaga     1620

gagaaaauag cagcuaaaaa ugcauuagaa ucauaugcau uuaauaugaa aagcguagua     1680

ucagacgaag gauuaaaagg aaaaauaagc gaaagugaua aaaacaaaau acuagacaaa     1740

ugcaaugaac uauuaucaug guuagaagua aaucagcuag cagaaaaaga ugaauuugac     1800

cauaaaagaa aggaacuaga acaaaugugu aauccaauaa uaacaaaauu auaccaaggg     1860

gguugcacag gaccugcaug uggaacagga uaugucccag gcagaccagc aacaggacca     1920

acgaucgaag aaguggauua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  2541
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt13)

<400>  2541
gggagaaagc uuaccauguc agcacguggg cccgcgauag guauagaucu agggacaaca       60

uacagcugcg uugggguguu ucaacacgga aaaguagaaa uaauagcaaa ugaucaaggu      120

aacagaacca caccaaguua cguugcauuu acagauacug aaagguuaau aggagacgca      180

gcgaaaaacc aaguagccau gaacccaaca aauacgaucu uugacgcaaa acgucuuaua      240

ggacguaaau uugaggacgc gaccguccaa agcgauauga aacacuggcc auuuagagua      300

guaagcgaag gaggaaaacc caagguacaa guagaauaca aaggagaaac aaaaaccuuu      360

uucccugaag aaauaucauc aaugguauua acaaaaauga aagaaauagc agaagccuac      420

cuugggggaa aaguccacuc agcaguaaua acgguaccag cauacuuuaa cgauagccag      480

agacaagcca caaaagaugc agggacaaua acaggacuca auguauuaag aauaauuaau      540

gagccuacag cagcagcaau agcauaugga uuagauaaga aaggaugugc ggguggggaa      600

aagaacguau uaauauuuga ccuaggugga ggaacauucg acguaaguau acuaacaaua      660

gaagauggaa ucuucgaagu gaaaaguaca gcaggagaua cucaccuggg cggagaagau      720

uuugauaauc gaaugguuuc acauuuagca gaagaguuca aacgaaagca caagaaagau      780

auaggaccaa acaaaagagc aguacgaaga uugcgaacag cgugcgaaag agcgaaaaga      840

acacugaguu caucaacaca agcgagcaua gaaauagacu cacuuuauga aggaguagau      900

uuuuauacaa guauaacacg cgcaagauuu gaagaguuaa augcagauuu auucagagga      960

acguuagaac cgguugagaa agcacuaaga gacgcaaaac uugacaaagg ccaaauacaa     1020

gaaauaguau uagucggcgg aucaacuaga auaccaaaaa uacaaaaacu acugcaagac     1080

uucuuuaaug gaaaagaacu caacaaaagc auaaauccag acgaagcagu cgcauauggu     1140

gcagcaguac aagcagcaau auuaauaggg gauaaaucag aaaacgugca agaucuacug     1200

uuacuagaug ucacaccacu aucacuaggu auagaaacag cagggggugu aaugacaccu     1260

cuaauaaaaa gaaauacaac cauuccaaca aaacaaacac aaacauuuac aaccuacuca     1320

gauaaucaau caagcguucu aguacaagua uaugaaggug aaagagcaau gacgaaggau     1380

aauaauuuau uaggaaaauu cgaucucaca gguauaccac cagcgccccg aggaguacca     1440

caaauugaag uaacuuuuga cauagaugca aacggaaucu uaaauguuac agcagcagau     1500

aaaagcaccg gaaaagaaaa uaaaaucacu auaacgaaug auaaaggaag auuaagcaaa     1560

gaugauauag auagaauggu acaagaagcg gaaagauaca aaagugaaga cgaagcaaau     1620

agagauagag uggcagccaa aaaugcacua gaaagcuaua cauauaauau caaacaaaca     1680

gucgaagaug aaaaacuaag aggaaagaua ucagaacaag auaaaaacaa aauauuggac     1740

aaaugucaag agguaauaaa cugguuagau agaaaucaaa uggcugaaaa ggaugaauau     1800

gaacauaaac aaaaagaauu agaaagagua ugcaauccua uaauaucaaa acuauaucaa     1860

ggaggaccag gaggaggaag cggaggagga ggaagcggcg caucaggugg accaaccaua     1920

gaggaaguag auuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  2542
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt13)

<400>  2542
gggagaaagc uuaccaugag uguuguuggu auugauuuag gcuuccaaag cugcuaugug       60

gcaguugcac gagcgggagg cauagaaaca auagcaaaug aauacagcga ucgaugcacc      120

cccgcaugua ucucauucgg accuaaaaac agaucaaucg gagcagcggc aaaaucacaa      180

guaauuucaa augcgaaaaa cacuguacag ggauucaaaa gauuucaugg aagggcauuc      240

agugacccau uuguagaagc ugaaaagagu aacuuggcuu augauauagu gcaacuacca      300

accggcuuaa caggaauaaa aguaacauac auggaagaag aaagaaacuu uacaacagaa      360

caaguuaccg caauguuacu uaguaaauua aaagaaacug cagaaagcgu guuaaagaaa      420

ccaguaguag auuguguugu gaguguaccc ugcuuuuaca cagaugcgga aaggagaucu      480

guaauggacg cuacacaaau agcgggacua aacugcuuaa gacuaaugaa ugaaacaaca      540

gcagucgcau uagccuacgg cauuuauaaa caagacuuac ccgcauuaga agaaaaacca      600

agaaacguag uuuuugugga caugggacac ucagcauauc aaguaucagu gugugcauuu      660

aauagaggca aacuaaaagu auuagcaaca gcauuugaca ccacacuagg aggaaggaaa      720

uucgaugaag uacuuguaaa ccauuucugu gaagaguucg gcaagaaaua uaaacuagau      780

auaaaaucaa aaauaagagc cuuauuacga cuuucacaag aaugugaaaa auuaaagaaa      840

cugaugucag caaaugccuc cgaucugcca cuaaguauag aaugcuucau gaaugaugua      900

gaugucucag gaacgaugaa ccgcgguaaa uuuuuagaaa ugugcaauga ucuauuggca      960

aggguagaac caccgcuuag aagcguccua gaacaaacca aacuaaagaa agaagauaua     1020

uaugcuguag aaauugucgg aggagcaaca agaaucccag caguaaaaga gaaaauaagu     1080

aaauucuuug gaaaagaauu aucaacaacg cuaaaugcag acgaagccgu aacacgagga     1140

ugcgcauuac agugugccau acuaagucca gcauucaaag uaagagaguu caguauaacc     1200

gacguuguac cauacccuau aaguuuaagg uggaauaguc ccgcagaaga agguagcuca     1260

gauugugaag uauuuucuaa aaaucacgca gcaccauuuu caaaaguauu aacauucuac     1320

agaaaagagc cuuuuacacu agaggcuuau uauucaucac cccaagaccu accauacccu     1380

gauccagcua uagcacaauu cagcguacaa aaagugacac cacaaagcga ugggaguagc     1440

ucaaaaguaa aaguaaaagu aagagucaac guacauggaa uauuuucagu aaguagugca     1500

agccuaguag aaguacauaa aucagaagaa aaugaagaac cuauggaaac agaucaaaac     1560

gcgaaagaag aagagaaaau gcaaguugau caagaagaac cccaugucga agaacaacaa     1620

caacaaacac cagcugaaaa uaaagcagaa agcgaggaaa uggaaaccag ccaagcugga     1680

uccaaagaca agaaaaugga ucaaccaccc caagcaaaga aagcaaaagu aaaaacuagc     1740

acagucgacu uaccaauaga aaaccaacuc cuauggcaga ucgacaggga aaugcuaaau     1800

cucuauauag aaaaugaggg aaaaaugaua augcaggaca aacuagaaaa agagaggaac     1860

gacgcuaaaa acgcaguaga agaauacgua uacgaaauga gagauaaacu aucaggggaa     1920

uaugaaaaau uuguaucuga agaugauaga aacaguuuua cauuaaaauu ggaagauacu     1980

gaaaacuggu uauacgaaga uggcgaagac caaccaaaac aaguauacgu cgacaaacua     2040

gcugaacuaa agaaucuagg ucaaccaaua aaaauaagau uccaagaauc agaagaaaga     2100

ccaaaauuau ucgaagaacu aggaaaacaa auacaacaau auaugaaaau aaucucauca     2160

uuuaaaaaua aagaagacca auacgaccau cuagaugcag cagauaugac aaaaguagaa     2220

aaaucuacua acgaagcaau ggaauggaug aauaauaaau uaaaccucca aaauaaacaa     2280

ucacugacga uggaucccgu uguuaaaagc aaagaaauag aggcaaaaau aaaagaacua     2340

acaagcacgu guagucccau aauaucaaaa ccaaaaccaa aaguagaacc cccaaaagaa     2400

gaacagaaaa augccgaaca aaauggucca guagauggac aaggagacaa uccaggccca     2460

caagcagcag aacaaggaac agauacagcc gugccaucag auagugacaa gaaauuacca     2520

gaaauggaua uugauuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  2543
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt13)

<400>  2543
gggagaaagc uuaccaugag cguuguuggc auagaucucg gauuccuaaa cugcuauaua       60

gccguagcua gaagcggugg aauagaaaca auagcgaacg aauacucgga ccgcugcaca      120

ccagcuugua ucagcuuagg aucccgcacc agagcaauag gcaaugcagc gaaaagccaa      180

auagugacaa acguacgaaa uacuauacau ggauuuaaaa aacuacacgg aaggaguuuc      240

gaugacccua uaguacaaac ggaaagaaua cgacucccau augaacuaca aaagaugccg      300

aauggaagug caggaguaaa aguaagauac cucgaagaag aaagacccuu ugcaauugaa      360

caaguaacug gaauguuacu agcaaaauua aaagaaacau cggaaaacgc auuaaaaaaa      420

ccgguugccg acugcguaau auccauccca aguuuuuuua cggaugcaga aagaagaagu      480

guaauggcgg cagcacaagu agcaggauua aauugccuaa ggcucaugaa cgaaacgaca      540

gcaguagcuu uagcauacgg aauuuauaaa caagauuugc caccauuaga ugagaaaccc      600

agaaauguag uauucauaga caugggacac ucugccuauc aaguacucgu uugugcauuc      660

aauaaaggca aauuaaaagu uuuagccaca acauucgauc ccuaccucgg cggaaggaau      720

uucgacgaag cauuaguaga uuauuuuugc gaugaauuca aaacaaaaua caaaauaaau      780

gugaaagaaa acuccagagc auuacucaga cuauaccaag aaugugaaaa acuaaaaaaa      840

cuaaugagcg caaaugcaag cgaccucccc cuaaacauag aaugcuuuau gaaugacuug      900

gacguaucuu caaaaaugaa cagagcccaa uucgagcaau uaugcgcguc auuacuagcc      960

cgaguagaac cuccacuuaa agcaguaaug gaacaagcaa acuuacaacg agaagauaua     1020

ucaucuauag agauuguagg aggagcaaca agaauccccg caguaaaaga acagaucacu     1080

aaguuuuuuu uaaaagacau uucuacaaca cucaaugccg augaagccgu ugcacgagga     1140

ugugcauuac aaugcgccau auuaucccca gcauuuaagg uaagagaauu cagcauuaca     1200

gaccugguuc cauauucaau aacauuaaga uggaaaacaa guuuugaaga cggaucaggu     1260

gaaugcgaag uauucugcaa aaaccaucca gcaccauucu cuaaaguaau uacauuccau     1320

aaaaaagaac cauuugaacu agaagcuuuu uauacuaacc uacacgaagu accauaccca     1380

gaugcaagga ucgguucauu uacaauacaa aacguguucc cgcaaagcga cggagacucu     1440

aguaaaguga aaguuaaagu aagagucaau auacauggaa uauuuucagu cgccucagcc     1500

ucagugauag aaaaacagaa cuuagaagga gaccauagug acgcuccuau ggaaacugaa     1560

acauccuuca aaaaugaaaa uaaagacaau auggauaaaa ugcaaguaga ccaggaagaa     1620

ggacaucaga aaugccaugc cgaacauacu ccugaggaag aaauagauca uacaggagca     1680

aaaacaaaau cggcaguauc agauaaacaa gacagauuaa aucaaacucu aaaaaaaggg     1740

aaaguuaaau caauagacuu accaauacaa ucgagcuuau gcagacaguu aggacaagac     1800

cuacuuaacu cauauauuga aaaugaaggc aaaaugauua ugcaagacaa auuagaaaag     1860

gagaggaacg augccaaaaa cgcagucgaa gaauacguau augacuucag agauagacua     1920

ggaacuguau augaaaaauu uauuacccca gaagacuuau cgaaacuaag cgccguucua     1980

gaagauacag aaaacuggcu guaugaggau ggagaagauc aacccaaaca aguauacguu     2040

gacaaacuac aagaauugaa aaaauacgga caaccaaucc aaaugaaaua cauggaacac     2100

gaagaaagac caaaagcauu aaaugaucuc ggaaaaaaaa uccaauuagu aaugaaagua     2160

auagaagccu aucguaauaa agaugaaaga uacgaucauc uagacccuac agaaauggaa     2220

aaaguagaaa aauguauauc agaugcaaug aguugguuaa auucaaaaau gaacgcacaa     2280

aauaaacuaa guuuaacgca agacccugua guaaaagucu cugaaaucgu agcaaaaagc     2340

aaagaacugg acaacuucug caaccccaua auauacaaac ccaaaccuaa agcagaggug     2400

ccagaagaca aacccaaagc aaauucugaa cauaacgguc caauggacgg acaaagcgga     2460

acagaaacaa aaucagacuc aacaaaagau aguucacaac auacaaaguc aucuggcgaa     2520

auggaaguug acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  2544
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt13)

<400>  2544
gggagaaagc uuaccaugaa auuaucuuua guagcggcaa ugcuauuacu acuaagcgca       60

gcaagggcag aggaagaaga uaaaaaagaa gacgucggaa caguagucgg uauagaccua      120

ggaaccacau auucaugcgu cggaguuuuu aaaaacggaa gaguugaaau cauagcaaac      180

gaucaaggaa acagaaucac accaucauac guagcguuca caccugaagg agaacgacuc      240

auaggagaug cagcaaaaaa ucaauuaaca ucuaacccug aaaacacagu cuuugacgca      300

aaaagauuga uaggaagaac cuggaacgac ccuucaguuc aacaagacau aaaauuucua      360

ccauuuaaag uaguagaaaa aaaaacaaaa ccauauauac aaguugauau uggaggcggu      420

caaacaaaaa cauucgcacc agaagaaaua uccgcaaugg uacuuacaaa aaugaaagaa      480

acagcugaag cauaccuagg aaaaaaagua acacaugccg uaguaacagu accagcauau      540

uuuaaugacg cccaaagaca agcaacaaag gaugcaggaa caauagcugg ucuaaacguc      600

augagaauaa uaaacgaacc aacagcagca gcuaucgcau acggacuaga uaaaagagaa      660

ggagaaaaaa auauacuagu auuugaucua ggaggaggaa cauucgaugu aagcuuauua      720

acaauagaca acggagucuu ugaaguagua gcuacaaacg gugacacaca uuuaggagga      780

gaagacuuug aucaaagagu uauggaacac uuuauaaaac uauauaaaaa aaaaaccggg      840

aaagacguaa ggaaagauaa cagggccgua cagaaacuca gaagagaagu cgaaaaagca      900

aaacgagcau uaucaucaca acaccaagca agaauagaaa uagaaaguuu cuaugaagga      960

gaagauuuua gcgaaacucu aacgcgagca aaauuugaag agcugaacau ggauuuauuu     1020

agaaguacca ugaaaccagu acaaaaagua cucgaagaca gugauuuaaa aaaaagugac     1080

auagacgaaa uaguccuagu aggagguuca acccgaaucc ccaaaauaca acaacucguc     1140

aaagaauuuu ucaacggaaa agaaccgagc cgaggaauaa acccugacga agcaguagca     1200

uauggcgcag caguucaagc aggcguauua agcggagauc aagauacagg agauuuagua     1260

cuacuagacg uauguccacu aacucuagga auagaaacag ucggaggagu aaugaccaaa     1320

uuaauaccua gaaacacagu aguaccgaca aaaaaaucac aaauuuucuc cacagcaagc     1380

gacaaucaac caacaguaac cauaaaagua uacgaaggcg aaagaccauu aacaaaagau     1440

aaccauuuau uaggaacauu ugauuuaaca gguaucccac cugccccacg aggaguccca     1500

caaauagaag uuacauuuga aauagaugua aaugguaucc ucagagucac agcggaagau     1560

aaaggcacug gaaauaagaa uaaaauuacu auaacaaacg accaaaauag auuaacuccc     1620

gaagaaauag aaagaauggu aaaugaugcg gaaaaauucg ccgaagagga caaaaaacua     1680

aaagagagaa uagauaccag aaacgaguua gaaucauacg cauacucccu uaagaaucaa     1740

auuggagaua aagaaaaauu aggcggcaaa uugagcucag aagacaaaga aaccauggaa     1800

aaagcaguag aagaaaaaau agaauggcuu gaaagccacc aggaugcaga uauagaagau     1860

uucaaagcaa aaaaaaaaga gcuagaggaa aucguacaac caauaauuuc aaaacuauac     1920

ggaagugcag ggccaccacc aacaggagaa gaagacaccg cagaaaaaga ugaacuuuaa     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  2545
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt13)

<400>  2545
gggagaaagc uuaccaugca agcaccacgu gaacuugcag ucgguauaga ucuaggaaca       60

acauauuccu guguaggagu auuucaacaa gggagaguag aaauauuagc aaacgaucaa      120

ggcaauagaa caacaccauc auauguagca uuuacugaca cagaaagauu gguaggagau      180

gcagccaaaa gucaagcagc auuaaaucca cauaacacag uguucgacgc gaaaagacua      240

auugguagaa aauuugcgga uacaacaguc caaagugaca ugaagcauug gccauuuagg      300

guagugucug aagguggaaa accaaaagua agaguaugcu auagagguga agauaaaaca      360

uuuuauccag aagaaauuuc aucaauggua uuaagcaaaa ugaaagagac agcagaagca      420

uaccuuggac aaccaguaaa acaugcugua auaacaguuc ccgcauacuu caaugauagc      480

caaagacaag caacaaaaga ugcuggagca auagcuggau uaaacgugcu aagaauuaua      540

aaugaaccaa ccgccgcggc aauugcauau ggauuagaua gaagaggagc aggagaaaga      600

aacguauuaa uauucgaucu aggaggagga acauuugacg uaucagucuu aucaauagac      660

gcaggcguau ucgaaguaaa agcaacagcu ggugauacuc acuuaggagg agaagauuuc      720

gauaacagau uaguuaauca cuucauggaa gaauuucgac gaaaacaugg caaagaucua      780

uccggcaaua aaagagcauu aagaagacua cgaacagcgu gugaaagagc aaaaagaaca      840

uuauccucau cuacccaagc uacauuagaa auagauagcc uauucgaagg gguagauuuu      900

uacacuucca uaacaagagc ucgcuucgag gaacuaugcu cagauuuauu uagaucuacu      960

uuagaaccug uagaaaaagc cuuacgugac gcaaaauuag auaaagcaca aauacaugac     1020

gucguauuag uagguggaag uacccgaaua ccaaaaguac aaaaacuauu acaagauuuc     1080

uuuaacggaa aagaacuaaa caaaucaauu aauccagaug aagcaguugc uuacggcgca     1140

gcaguacagg cagcaguauu aaugggagau aaaugugaaa aaguacaaga uuuguuacuu     1200

cuagacgugg caccccuaag ccuaggauua gaaacagcag gaggaguaau gaccacauua     1260

auacaaagaa augcaacaau accuacuaaa caaacacaaa cauuuacaac auauagugac     1320

aaucaaccug ggguauucau acaaguauau gaaggugaaa gagcaaugac aaaagauaau     1380

aauuuacuag guagauuuga auuaucaggg auuccaccag caccacgagg aguaccgcaa     1440

auagagguga cuuuugacau agacgcaaau ggcaucuuaa gcguaacagc aacagauaga     1500

agcacaggaa aagcaaacaa aauaacaaua acaaaugaca aaggaagguu aagcaaagag     1560

gaggucgaaa ggaugguaca ugaagcagag caauauaagg ccgaagauga agcccaaaga     1620

gacagaguag cagcuaaaaa uucacuagaa gcacaugugu uucacguaaa agggagcuua     1680

caagaagaga guuuaagaga uaaaauacca gaagaagaua gacgaaaaau gcaagauaaa     1740

ugcagagaag uauuagcaug gcuagaacau aaucaacugg cagaaaaaga agaauaugaa     1800

caucaaaaac gagaauuaga acaaauaugc agaccaauau ucucaaggcu auauggcgga     1860

ccaggaguac caggaggaag uucuugugga acucaagcua gacaaggaga cccuucuaca     1920

ggaccaauaa uugaagaagu agauuaagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  2546
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt13)

<400>  2546
gggagaaagc uuaccaugca agcacccaga gaauuagccg uaggaauaga ccuaggaacu       60

acauauagcu gugucggagu auuucaacaa ggaagaguug aaauauuagc aaaugaccaa      120

ggaaauagaa caacaccuuc auauguagca uucacagaca cagaaagguu aguaggagau      180

gccgcgaaaa gccaagcagc auuaaaccca cacaauacag uauucgaugc aaaaagacuc      240

aucggaagaa aauuugcaga uacaacagua caaucagaua ugaaacauug gccauuucaa      300

guagucucag aaggcggaaa accaaaagua agaguauguu acagaggaga agauaaaaca      360

uuuuauccag aagaaauauc aaguauggua uuaucaaaga ugaaagaaac agcagaagca      420

uaucuaggcc aaccaguaaa acaugcagua auaacaguac caacuuauuu cucaaauuca      480

caaagacaag caacaaaaga ugcuggagca auugcagguc uaaaaguauu accaaucaua      540

aaugaagcua cagcugcagc aauagcauau ggccuagaua gaagaggagc aggaaaaaga      600

aauguauuaa uauuugauuu aggaggagga accuuugacg uaucaguauu aucaauagau      660

gcaggaguau uugaaguaaa agcaacagcc ggagauacac aucuaggagg agaagauuuc      720

gacaacagau uaguuaauca cuucauggaa gaauuuagaa gaaaacacgg aaaagacuua      780

ucagguaaua aaagagcacu uagaagauua agaacagcau gugaaagagc caaaagaaca      840

ccaucaagcu caacacaagc gacauuagaa aucgauucac uauucgaagg aguagauuuu      900

uauaaaucaa uaacuagagc ccgauuugaa gaauuauguu cagacuuauu ucgaagcaca      960

cuagaaccag uagaaaaagc acuaagagau gcaaaacuag acaaagcaca aauacacgac     1020

uucguauuag gaggaggacu acacagucau ccacaaggag cugaaguagc ugcaggauua     1080

uuacaaagac aaggagcaga acaagaacac caaccuuaag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  2547
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt13)

<400>  2547
gggagaaagc uuaccauguc aaaagguccu gcuguaggaa uugacuuagg aacgacauau       60

ucguguguug gugucuucca acaugggaaa guagaaauua uagcaaacga ucaaggaaac      120

cgaacaacac caucauacgu agcuuuuaca gauacagaaa gauuaaucgg agacgcggcu      180

aaaaaucaag uagcaaugaa uccaacaaac acagucuuug acgcaaaacg acuaauagga      240

agaagauuug augaugcagu aguucaaagc gauaugaaac acuggccauu uaugguagua      300

aaugacgcag gaaggccaaa aguacaagua gaauacaaag gagaaacaaa gagcuucuau      360

ccggaagaag uaucaagcau gguauuaaca aaaaugaaag agauagcaga ggcauacuua      420

ggaaaaacag uaacaaacgc aguagucaca guuccagcau auuucaacga uagccaaaga      480

caagcaacaa aagacgcagg uacaauagca ggauuaaaug uacuccggau aauaaacgaa      540

ccaacagcug cugcaaucgc guauggacua gauaagaaag uaggcgcaga aagaaaugua      600

uuaaucuucg acuuaggagg aggaacauuc gauguaucua uucuaacaau agaagacggc      660

auauucgaag uaaaaagcac agccggcgac acacacuuag gaggagaaga uuucgauaac      720

cgaaugguaa accauuucau agccgaguuc aaaaggaaac acaagaaaga cauaagugaa      780

aauaaaagag caguacgccg auuaagaacc gcaugugaaa gagcaaaaag aacucuaagu      840

ucaagcacac aagcgaguau agaaauagac aguuuauaug aagguauaga uuuuuauaca      900

ucaauaacaa gagcaagauu cgaagaacuu aacgcagacc uauuuagagg aacacuagac      960

ccaguagaaa aagcacuaag agaugcaaaa uuagacaaaa gccaaauaca ugauauagua     1020

uuggucggag gaucgacuag aaucccaaaa auacaaaaac uauuacaaga cuucuuuaac     1080

ggaaaagaac ucaauaaauc gauuaaucca gaugaagcag ucgcauaugg agcugcggua     1140

caagccgcga uauuaagcgg agacaaaucc gaaaacgucc aagaucuauu acucuuagac     1200

guaacaccuc ugucgcuagg aauugaaaca gccggugggg uaaugacagu acuaauaaaa     1260

agaaacacca caauaccaac uaaacaaaca caaacauuua cuacauacuc agauaaucaa     1320

ccaggagucc uaauucaagu uuacgaaggg gaacgugcaa ugacaaaaga caauaauuua     1380

cucggaaaau uugaacuaac aggaauacca ccagcaccaa gaggaguacc acaaauagaa     1440

guaacauuug auauagaugc aaauggaaua cuaaacguaa gugcgguaga uaaaagcaca     1500

gguaaagaaa acaaaauaac aauaacuaac gacaaaggca gauuaucaaa agaagauaua     1560

gaaagaaugg ugcaagaagc agaaaaauau aaagcagaag acgaaaaaca aagagauaaa     1620

guaaguagua aaaauucauu agaaucauac gcauuuaaua ugaaagcaac gguagaagau     1680

gaaaaauugc aaggaaaaau aaacgaugaa gauaagcaga aaauuuuaga caaauguaac     1740

gaaauuauaa auugguuaga uaaaaaucaa acagcagaga aagaggaauu ugaacaucaa     1800

caaaaagaau uggaaaaggu cugcaauccu auaauaacca aauuauacca aucugcggga     1860

ggaaugccag gcggaaugcc aggaggauuc ccagguggag gagcuccacc aagcggagga     1920

gcaagcagug gaccaacaau agaagaaguc gauuaaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  2548
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt13)

<400>  2548
gggagaaagc uuaccaugau cagugcaagc agagcugccg cagcaagauu aguaggagcg       60

gcagcaagca gaggaccaac cgcugcuaga caucaagaua guuggaaugg auuaucacac      120

gaagcauuua gacucguaag uagacgagac uaugcaagcg aggcaauaaa aggcgcagua      180

guagggaucg auuuagggac gacaaacuca ugcguagcag ucauggaagg aaaacaagca      240

aaaguacuag aaaaugcaga aggagcgaga acaacaccau caguaguagc guuuacugca      300

gauggagaaa ggcuaguagg caugcccgcu aaaagacaag caguaacaaa uccaaauaau      360

acauuuuaug caacaaaaag auuaauagga agaagauaug augacccaga gguacagaaa      420

gacaucaaaa auguaccuuu uaaaauagua agagcaagua acggagacgc auggguagaa      480

gcacauggua aacuauauag uccgucgcaa auaggagcau uuguucuuau gaaaaugaaa      540

gaaacggcag aaaauuaucu agggcauaca gccaagaacg caguaauaac aguacccgca      600

uauuucaacg auucacagcg ucaagcaacg aaagaugcgg gacaaauuag ugggcugaau      660

guauuaagag uaauaaacga acccacagcu gcagcccuag cguauggacu cgauaaauca      720

gaagacaaag uaaucgcagu auaugauuua ggugggggaa ccuuugacau uucaauauua      780

gaaauacaaa aaggcguauu ugaaguaaaa aguacaaaug gagauacauu cuuaggagga      840

gaagacuucg aucaagcucu auuacgacau auagugaaag aguucaaaag agaaacagga      900

guugacuuaa caaaagauaa cauggcacua caaagaguaa gagaagcagc ugaaaaagcg      960

aaaugcgaac uaaguaguag uguacaaaca gacauaaacu uaccauacuu aacaauggac     1020

ucaucagggc caaaacaucu uaacaugaaa cugacuagag cacaauucga aggaauaguc     1080

accgaucuaa uacguaggac cauugcacca ugccagaaag caaugcagga cgcagaagua     1140

ucgaaaagcg auauaggaga aguaauauua guugggggaa ugacaagaau gccuaaagua     1200

caacaaacag uacaagauuu auuuggaagg gcaccaucaa aagcaguaaa cccagacgaa     1260

gcaguggcga uaggagccgc aauacaagga ggaguacuag caggagacgu aacugauguu     1320

uuauuacuag auguaacccc acuaaguuug ggaauagaaa cauuaggagg aguauuuaca     1380

aaacuaauaa auagaaauac cacaauaccu acaaagaaau cucaaguauu uucaacagca     1440

gcagacggcc aaacacaagu ggaaauaaaa guaugucaag gcgaaagaga aauggcagga     1500

gacaauaaac uguuaggaca auuuacuuua auagguauac caccagcacc aaggggagua     1560

ccucaaauug aaguaacauu cgacauagac gcaaauggaa uaguccaugu aucagcgaaa     1620

gauaagggca cagggaggga acaacaaaua guaauacaaa guagcggagg acugaguaaa     1680

gacgauauag aaaauauggu caaaaaugcu gaaaaauaug cugaagagga uaggaggaag     1740

aaagaaaggg uagaagcggu aaauauggca gaaggaauaa uacaugacac agaaacaaaa     1800

auggaagaau uuaaagauca auuaccagcg gaugaaugua auaaacucaa agaagaaaua     1860

aguaaaauga gagaguuacu ugcaagaaaa gauucagaaa cgggagaaaa uauacgacaa     1920

gcagcaaguu cacuacaaca agcuagucua aaauuauucg aaauggccua uaagaaaaug     1980

gcaucggaac gagaaggauc aggaucaucu gguacagggg aacaaaaaga agaucaaaaa     2040

gaagaaaaac aauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  2549
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt13)

<400>  2549
gggagaaagc uuaccauggc ugauaaagaa gccggaggau cugauggccc uagagaaacc       60

gcaccaacuu cagcauauag cagccccgcc agaucauuag gagauacagg cauaacuccc      120

uuaucaccau cccauauagu aaacgauaca gauaguaaug ucuccgaaca acaaucauuu      180

uugguuguug uagcagucga uuucgguaca acaagcuccg gauacgcaua uuccuucaca      240

aaagaaccgg aauguauaca uguuaugaga agaugggaag gcggcgaccc aggaguuagu      300

aaccaaaaga cuccaacuac aauccucuua acaccggaaa ggaaauucca uucauucgga      360

uaugccgcac gcgauuuuua ccacgauuua gacccaaacg aagcgaaaca augguuauau      420

cuagaaaaau uuaaaaugaa acuacauacc acaggagacc uuacuaugga uacagaccua      480

acagcugcaa auggaaagaa aguaaaagca uuagaaaucu uugcauacgc guuacaauac      540

uuuaaagaac aagccuuaaa agaauuaagc gaccaagcug gaucagaauu ugaaaauucc      600

gacguacgau gggucauaac gguaccugca auauggaaac aaccagcaaa acaauucaug      660

agacaagccg ccuaucaagc uggacuagcg ucaccagaaa acagcgaaca acuaauaaua      720

gcacuagaac cagaagcagc aucaaucuau uguagaaaac uaagauuaca ucaaaugaua      780

gaacuaucau caaaagcugc aguaaaugga uauucaggaa gugacaccgu aggugcagga      840

uuuacucaag ccaaagaaca cauaagaaga aauagacaau cuagaaccuu ucuagucgaa      900

aauguaauug gcgaaauaug gucugaauua gaagaaggag acaaauaugu cguaguugac      960

uccgguggag gaacagugga ucucaccguc caucaaauac gacuaccaga aggacaucuu     1020

aaagaacucu acaaagcuac aggaggacca uauggcucau uaggcguaga uuaugaauuu     1080

gaaaaacugc uauacaaaau cuucggagaa gacuuuauag aacaauuuaa aaucaaaaga     1140

ccagcagcau ggguagauuu aaugauagca uucgaaucaa gaaaaagagc ugcagcacca     1200

gaucgaacua auccguuaaa uauaacguua ccauucucau ucauugacua cuauaaaaag     1260

uuuagagguc auaguguuga acaugcacua agaaaaucga auguagauuu uguaaaaugg     1320

ucaagucaag gcauguuaag aaugucacca gaugccauga augcauuauu uaaaccaacu     1380

auagauucaa uaauagaaca uuuaagagac uuauuccaaa aaccagaagu aucuacaguu     1440

aaauucuuau uccuaguagg gggauuugca gaagcuccac uucuacaaca agcagugcaa     1500

gcagcauucg gcgaccaaug ucgaauaaua auaccucaag acguaggccu cacaauacua     1560

aaaggagcgg uauuauuugg auuagauccu gcagucauaa aaguaagaag aucaccucua     1620

acauacggug uaggaguacu aaacagguac guagaaggaa aacacccacc ugaaaaacuu     1680

uuagucaaag acggaacuag auggugcaca gauguauuug auaaauucau aucagcagau     1740

caaucaguag cauuaggaga acugguaaaa cgaucauaca cuccugcuaa acccagccaa     1800

uuaguaaucg uaauaaauau auauucaagu gaacaugaua augucucauu uauaacagau     1860

ccaggaguaa agaaaugcgg aacauugaga uuggaccuca caggaacauc aggaacagcu     1920

guaccagcaa gacgagaaau ucaaacacua augcaauuug gagauaccga aauaaaagca     1980

acugcaauag auauagccac cagcaaaagu guaaaagugg gaaucgauuu cuuaaauuau     2040

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  2550
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt13)

<400>  2550
gggagaaagc uuaccaugcu agcaguaccu gaaaugggau uacaaggucu auauauaggu       60

agcucgccag aacgaucacc aguaccaagu ccgccgggau caccucgcac acaagaaagc      120

uguggaauug caccacuaac cccuucucaa ucaccaaagc cagaaguuag agcaccccaa      180

caggcuucau uuucuguagu aguagcaaua gacuuuggca ccacauccuc aggcuaugcc      240

uucagcuuug caucagaccc agaagcgaua cauaugauga ggaaauggga aggaggagau      300

ccagggguag cacaucagaa aacaccuacu ugcuuauuac uaacaccaga aggcgcauuu      360

cauaguuuug gauauacagc aagagacuau uaucaugauc uggauccuga agaagcgcgu      420

gauugguuau auuuugaaaa auuuaaaaug aaaauccauu cagcaacaga ucuaacuuua      480

aaaacacaau uagaagcugu caauggcaaa acaaugccag cauuagaagu auuugcccau      540

gcacuaagau uuuuccgaga acaugcacua caagaacuua gagaacaauc cccaaguuua      600

ccugagaaag auacaguaag auggguauua acagugccgg caauauggaa acaaccugcu      660

aaacaauuca ugagggaagc cgccuauuua gcaggauugg uuucacgaga aaacgcagaa      720

caacuauuga uagcuuuaga gccagaggcg gcaaguguau auuguagaaa acuaagauua      780

caucaacuac uagauuuauc aggcagagcu ccaggaggag guagauuagg agaaagacga      840

uccauugauu cuaguuuuag acaagcuaga gaacaacuaa gaagaagcag acauucaaga      900

acauuccuug uagaaagugg aguaggagaa uuaugggcag aaaugcaagc aggagauaga      960

uauguaguug cagacugugg aggaggaacu guagaccuca caguucauca acuagaacaa     1020

ccacauggua cccuaaaaga auuauauaaa gcgaguggcg gcccauacgg agcaguaggc     1080

guagauuuag cauuugaaca auuacucugu cgaauauuug gagaagauuu cauagcuacu     1140

uuuaaaagac aaagaccagc ugcaugggua gaucuaacua uagcuuucga agcaagaaaa     1200

agaacagccg gaccucauag agcaggagca uuaaauauau cucuaccauu uaguuuuaua     1260

gauuuuuaca gaaaacaacg gggacauaac guagaaacgg cauuacgaag aucaaguguc     1320

aacuucguaa aauggucauc acaagguaug uuaagaaugu ccugugaagc aaugaaugaa     1380

cuauuucaac ccacuguaag cggaauaaua caacacauag aagcauuauu agcaagaccc     1440

gaaguucaag gaguaaaauu acuauuucua guaggagggu uugccgaauc ggcaguucua     1500

caacaugcag uacaagcugc guuaggcgca cgaggauuac gaguaguagu accccacgau     1560

guugggcuua caauucugaa aggagcugua uuauuuggac aggcaccagg aguagucaga     1620

guuagaagaa gcccacuaac auauggggua ggaguacuua acagauuugu accaggcagg     1680

cauccuccag aaaaauuauu aguacgagac ggaagacguu gguguacaga uguauucgaa     1740

agauucguug cagcugaaca aagcguugca uuaggagaag aaguaagacg aucauauugc     1800

ccagcuagac caggucaaag aagaguucua auaaacuuau auuguugcgc cgcagaagau     1860

gcaagguuua uuacugaucc uggaguucga aaauguggug cacuuagccu agaacuagaa     1920

ccggccgauu guggacaaga uacagccgga gcaccaccag guagaagaga aauaagagcu     1980

gcuaugcaau ucggagacac cgaaauaaaa gucacagcag uagaugucag cacaaauaga     2040

ucagugcgag cuaguauaga cuuucuauca aauugaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  2551
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt13)

<400>  2551
gggagaaagc uuaccauggc acgagaaaug accauauuag gaagcgccgu auuaacauua       60

uuacuagcgg gauauuuagc acaacaauau cuaccccuac ccacaccaaa aguaaucgga      120

auagacuuag gaacaacaua uuguagugua ggaguuuucu ucccaggaac cggaaaaguc      180

aaaguaauac cagacgaaaa cggacacaua ucaauuccau caaugguauc auuuacugau      240

aacgacguau auguaggaua cgaaucagua gaauuagccg auagcaaucc acaaaacacu      300

auauaugacg caaaaagauu cauaggcaaa auauuuacag cagaagaacu ugaagcugaa      360

auaggaagau aucccuuuaa aguacuaaau aaaaacggaa ugguagaauu cucaguuaca      420

ucaaaugaaa caauaacagu caguccagaa uacguaggua gcagauuacu acuaaaacua      480

aaagaaaugg cagaagcaua cuuaggaaug ccaguagcaa augccguaau aucuguacca      540

gcagaauucg auuuaaaaca acgaaauuca acaauagaag cagcuaaucu agcaggacua      600

aaaauauuaa gaguuauaaa cgaacccaca gcagcagcaa uggccuaugg auuacacaaa      660

gcugacguau uucauguacu aguaauagau cuagguggag guacauuaga cguaagcuua      720

cuaaauaaac aaggaggcau guuucuuaca cgagcaaugu caggcaacaa caaauuagga      780

ggucaagacu uuaaccaaag acuacuacaa uaucucuaca aacaaauuua ccaaacuuau      840

ggauuuguuc cuucaagaaa agaagaaaua caucgauuac gacaagcagu agagauggua      900

aaacuaaauu uaacacuaca ucagagugca caacuuuccg ucuuauuaac aguugaagaa      960

caagaucgaa aagaaccaca caguucagac accgaacuuc caaaagauaa auuaagcuca     1020

gcagaugacc auagaguuaa cagcggcuuu ggaagaggau uaucagacaa aaaaagcgga     1080

gaaagccaag ugcuguuuga aaccgaaaua agcagaaaau uauucgauac acuuaacgaa     1140

gaccuauucc aaaaaauauu aguaccaauc caacaaguac uaaaagaagg ucaucuagaa     1200

aaaacagaaa uagaugaggu aguauuagua ggaggaucaa cacguauacc cagaauaaga     1260

caaguaauac aggaauuuuu cggaaaagau ccaaauacau caguagaccc agauuuagcg     1320

guuguuacag gagucgcaau acaagcagga auagauggcg gaagcuggcc auuacaagua     1380

uccgcacuag agaucccaaa caaacaucua caaaaaacca auuucaauua aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2552
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt13)

<400>  2552
gggagaaagc uuaccauggc agcaauagga guacauuuag gauguacaag ugcaugugua       60

gcaguauaua aagauggaag agcaggagua guagccaaug augcagggga uagaguaaca      120

ccagcgguag uagcuuauuc agaaaaugaa gaaauaguag gauuagcugc aaaacaauca      180

agaauaagaa auauuaguaa caccguaaug aaagugaaac aaauacuagg aagaucuuca      240

ucagaucccc aagcacaaaa auauauagca gaaucaaaau gucuaguaau agaaaaaaau      300

ggcaaacuaa gauaugaaau agauacaggc gaagaaacaa aauuuguaaa cccugaagau      360

gucgcuagac uaauauucuc aaaaaugaaa gaaacagcac auucaguacu aggaucagau      420

gcaaaugacg uaguaauaac cguaccauuu gauuuuggag aaaaacaaaa aaaugcauua      480

ggagaagcag caagagcagc aggauuuaac guguuacgac uuauacauga acccucagca      540

gcauuauuag ccuauggaau aggucaagac ucaccaacag gcaaaucaaa uauauuagua      600

uuuaaauuag gaggaacuag ucuaucacuc ucaguaaugg aaguaaauuc aggaauauac      660

agaguuuuau caacuaauac agaugauaau auuggaggag cacauuuuac agaaacauua      720

gcucaauacc uugcaaguga auuucaaaga aguuuuaaac acgaugucag aggaaaugca      780

agagcaauga ugaaacuaac gaauucagca gaaguagcaa aacauucauu aucaacauua      840

gggucugcca auuguuuccu agauagucuu uaugaagggc aagacuuuga cuguaaugua      900

agucgagcaa gauuugaacu acuguguuca ccccuguuua acaagugcau agaagcaaua      960

aggggauuac uagaucaaaa uggcuucacc gcagaugaca ucaauaaagu aguacuaugu     1020

ggaggaagcu caagaauacc aaaacuccaa caauuaauaa aagauuuauu ucccgcugua     1080

gaacuacuaa auaguauacc cccagaugaa guaauaccaa uaggugccgc aauagaagca     1140

ggcauauuaa uaggcaaaga gaaucuacua guggaagaca gucuaaugau agaauguagu     1200

gcaagagaca uauuaguaaa agggguagau gaaaguggag caagcagauu uacaguauua     1260

uuccccagcg gaacaccucu accagcaaga agacaacaua cucuacaagc gccagguuca     1320

auaucaucag uuugccuaga acuauacgaa ucagacggua aaaacucagc aaaagaagaa     1380

acaaaauucg cucaaguagu acuacaagau uuggacaaaa aagagaaugg acuaagagau     1440

auucuagccg uauugacuau gaaaagagau ggaucacuac acguaacaug uacagaccaa     1500

gaaacaggaa aaugugaagc aaucucuaua gaaauagccu cauaaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  2553
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt13)

<400>  2553
gggagaaagc uuaccaugag uguugugggg cuagacguag ggagccaaag uugcuauaua       60

gcaguagcca gagccggagg aauagaaacg auagcaaaug aauucucaga uagaugcacc      120

ccaaguguaa uaucauucgg aucaaaaaac aggacgauag gaguggcagc caaaaaucaa      180

cagauaacgc acgcaaauaa cacagucagc aacuuuaaaa gauuucacgg aagagcauuu      240

aacgacccau uuauacaaaa agaaaaagag aaucuaaguu acgacuuagu cccccuaaaa      300

aauggaggag ugggaauaaa aguaauguau augggcgaag aacaccuuuu uucaguugaa      360

caaauaacug cgaugcuauu aacaaaacua aaagaaacag cagaaaacuc auuaaaaaaa      420

ccaguaacag acugcguaau aucaguacca ucauucuuua cagacgcuga acgacgaagu      480

guucuagacg cagcacagau aguagguuug aauugucuaa gacugaugaa cgacaugaca      540

gcaguagcgu uaaacuacgg aauauacaaa caggaccuac caagcuugga cgagaaaccu      600

agaauaguag uauucguaga cauggggcac ucugcauucc aaguuagugc augcgcauuc      660

aauaaaggua aacucaaagu auuaggaaca gcauuugacc cauucuuagg aggcaaaaac      720

uuugacgaaa aacuuguuga acauuucugc gcggaauuca aaacaaaaua uaaauuggac      780

gccaaaagca aaauaagagc ccuuuuacga cuauaccaag agugcgaaaa acuaaaaaaa      840

cuaaugagua guaauucaac ugaccuacca cucaauauug aguguuucau gaaugauaaa      900

gauguaagug gcaaaaugaa cagaucucaa uucgaagaau uaugcgccga auugcuacag      960

aaaauagagg uaccacuaua uagccuccua gaacaaacac aucuaaaagu agaagauguu     1020

agugcagugg aaauaguagg aggcgcuaca agaauaccug caguuaaaga aagaaucgcu     1080

aaauucuucg gaaaagauau auccacaaca cuuaaugcag acgaagcagu agcucgcggc     1140

ugcgcucucc aaugugccau ucuaagucca gccuucaaag ucagagaauu cucuguaacu     1200

gacgcaguuc cguucccuau aucacuuaua uggaaccacg acagugaaga uacugaagga     1260

gugcaugaag uauucagcag gaaccaugcc gcuccuuuca gcaaaguauu aacuuucuua     1320

cgaaggggac cauucgaauu agaagcauuu uacucagauc cacaaggagu accauacccu     1380

gaagcaaaaa uaggccgauu cguaguacaa aacgucagcg cacaaaaaga uggagaaaaa     1440

ucaagaguca aaguaaaggu acguguaaau acccacggua uuuucacaau aucaacagca     1500

uccaugguag aaaaaguacc uacagaagaa aaugaaaugu caagcgaagc agauauggaa     1560

ugcuuaaauc aaagaccacc agaaaaccca gauacagaca aaaacguaca acaagauaac     1620

ucagaagcag gaacacaacc acaaguacaa accgaugcuc aacaaaccuc acaaucaccu     1680

ccaagcccag aacuuacuuc ugaagaaaac aaaaucccag acgcagauaa agccaacgaa     1740

aaaaaagucg accaaccacc agaagcuaaa aaaccaaaaa uaaaaguagu aaacguagaa     1800

cugcccauag aagcaaaccu aguauggcaa cuaggaaaag auuuauuaaa cauguacaua     1860

gaaacugaag gcaaaaugau caugcaagau aaacuagaaa aagaacgcaa ugacgcaaaa     1920

aacgcaguag aagaauaugu auaugaauuu agagacaaau uauguggacc auaugaaaaa     1980

uucauaugcg aacaagauca ccaaaauuuc cuacgacuac ucacugaaac agaagacugg     2040

uuauaugaag aaggagaaga ccaagcaaaa caagcuuacg uagacaaacu ggaagaacua     2100

augaaaauag guacgccugu aaaaguacgu uuccaagaag cagaagaaag accgaaaaug     2160

uuugaagaau uaggacagag acuccaacac uaugcaaaaa uagcugcaga cuuccgaaac     2220

aaagaugaaa aauauaacca cauagaugaa agcgaaauga aaaaaguuga aaaaucaguc     2280

aacgaaguaa uggaauggau gaacaacgua augaaugcac aagcaaaaaa aagucuagac     2340

caagacccag uagucagggc gcaagagaua aaaacgaaaa ucaaagaauu aaauaacacu     2400

ugcgaacccg ucguaacgca accaaaaccu aaaauagaau caccaaaacu agagcgcacg     2460

ccuaaugguc caaacauaga caaaaaagaa gaggaccuag aagauaaaaa uaacuuuggu     2520

gcagaacccc cccaucaaaa cggagaaugc uauccaaacg aaaaaaauag uguaaauaug     2580

gaucuagacu aaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  2554
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt13)

<400>  2554
gggagaaagc uuaccauggc ugauaaagua agaagacaaa gacccagaag gagaguuugu       60

ugggcucuag uagcaguauu acuggcagau uuauuagccu uaucagauac ccuugcagua      120

auguccguag accuaggaag ugaaaguaug aaaguagcaa uaguuaaacc cggaguacca      180

auggaaauag uccuuaacaa agaaucuaga aggaaaacuc caguuauagu aacacuaaaa      240

gaaaaugaac gauucuucgg cgacagugca gcaucaaugg ccaucaaaaa uccaaaagca      300

acauuaagau acuuucaaca ucuucuuggc aaacaagcug auaauccuca ugucgcauua      360

uaucaagcaa gauuccccga acacgaacua acuuuugacc cacaacguca aacuguacac      420

uuucaaauaa guucacaacu acaauuuagu ccagaagaag uacucggaau gguccugaau      480

uauucaagau cauuagcaga agauuucgca gaacaaccua uaaaagacgc aguaauaacc      540

guuccugugu ucuuuaacca agccgaaagg cgagcaguau uacaagcagc ucgaauggca      600

ggauuaaaag ucuuacaauu gauaaaugau aauacagcaa cagcacuuag uuacggggua      660

uuuagacgaa aagauaucaa uacgacagcu caaaauauaa uguuuuauga caugggaagu      720

ggcucaacag ucugcacaau aguaacauau caaaugguca aaacaaaaga agccgggaug      780

caaccacaac ugcaaauacg agguguagga uucgauagaa ccuuaggggg acuagaaaug      840

gaauuaagau uacgagaaag auuagcagga uuauuuaacg aacaaaggaa aggccaacgu      900

gcaaaggaug uaagagaaaa uccaagagcg auggcaaaac uccugagaga ggcuaauagg      960

cuaaaaacgg ugcuaagcgc aaaugcggac cauauggcac aaauagaagg guuaauggau     1020

gacguagacu uuaaagccaa aguaacacgc guagaguucg aagaauuaug ugcugaucua     1080

uuugaaagag uaccgggucc aguucaacaa gcguuacaau cggcagaaau gucacuugau     1140

gaaauagaac aaguaauuuu aguagggggc gcuaccaggg uuccuagggu acaagaaguc     1200

cuauugaaag ccguggggaa agaagaauua gguaagaaua uaaacgcaga ugaagcugcu     1260

gcaaugggug caguguauca agcagcagca cuaagcaagg cauuuaaggu gaaaccguuc     1320

guuguaaggg augcuguagu cuauccaaua uuaguagaau uuacucgcga aguagaagaa     1380

gaaccaggaa uacauuccuu aaaacauaau aaaagagucu uauucagcag gaugggaccc     1440

uauccucaga gaaaaguaau aaccuucaac cgauacaguc augacuucaa uuuccacaua     1500

aacuauggag auuuaggauu ucuugguccg gaagacuuaa gaguauuugg aagucaaaau     1560

cuaacaaccg uaaaauuaaa aggcguggga gacucauuua agaaguaucc cgauuacgaa     1620

ucaaaaggaa uuaaggcaca uuuuaacuua gacgagagcg gagucuuaag ccuggacaga     1680

guggaaucag uauucgaaac guugguugaa gauucagcug aagaagaaag uacacuaacg     1740

aaauugggaa acaccauaag uucucuauuc ggaggaggca caacuccaga ugcaaaagaa     1800

aaugguacag auacugucca agaagaagaa gaaucaccag cagaaggauc caaggacgaa     1860

ccaggagagc aaguugaacu uaaagaagaa gcagaagcac ccguugaaga uggaucacaa     1920

ccuccaccac ccgaaccgaa aggagacgcc acgccggaag gagaaaaagc aacugaaaaa     1980

gaaaauggag auaaaucaga agcacaaaaa ccaucugaaa aagccgaggc aggaccagaa     2040

gguguagcuc ccgcuccgga aggugaaaag aaacaaaaac cagcacgaaa aagacgcaug     2100

gucgaagaaa uaggaguaga auuaguaguu uuagacuuac cugaucuccc agaagacaaa     2160

cucgcacaau caguacaaaa acuacaagau cuaacauuga gagaucugga gaaacaagaa     2220

agagaaaaag cagcuaauag ucuagaggcu uucauuuucg aaacccaaga caaauuauac     2280

caaccugaau accaggaagu uuccacagaa gaacaaaggg aagaaaucag ugguaaauug     2340

agcgcagcua guacaugguu agaagaugaa ggaguuggag caacgacagu aauguuaaaa     2400

gaaaaauuag cagaauuaag gaaauuaugu caaggacucu ucuuuagagu cgaagaaaga     2460

aagaaauggc ccgagagauu gucagcauua gacaauuuau uaaaccauuc cagcauguuc     2520

uuaaaaggug ccagacuuau accagaaaug gaucagauau uuacagaagu ggaaaugacu     2580

acacuagaaa aaguaauuaa cgaaaccugg gcauggaaaa augcaacacu agcagaacaa     2640

gccaaauuac cggcgacgga gaaaccagua cuauuaucga aagauauaga agcaaaaaug     2700

auggcucuag accgagaagu ccaauaccuu uuaaacaaag ccaaauuuac aaaaccaagg     2760

ccaagaccua aagacaaaaa uggaacaaga gcggaaccac cacuaaacgc gagcgcaagu     2820

gaccaaggug aaaaaguaau uccaccagcu ggacaaacag aagacgcuga acccauaagu     2880

gaaccagaaa aaguagaaac aggaucagaa cccggagaua cugaaccacu agaguuggga     2940

ggaccagggg cugagcccga acaaaaagaa caaucaacag gccagaaaag accgcucaaa     3000

aacgaugaac uauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  2555
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt13)

<400>  2555
gggagaaagc uuaccaugcc agaagaaacg caaacacagg accaaccaau ggaagaagaa       60

gaaguugaaa cauuugccuu ccaagcugaa aucgcucaac uaaugucccu cauaauaaac      120

acauuuuaca guaauaagga aauauuccua cgagaauuaa uaucaaauag uagugacgca      180

uuagauaaaa uacguuacga aagccuaaca gauccgagua aacuagacuc aggaaaagaa      240

cuacacauaa acuuaauacc aaacaaacaa gaccgaacac ucacaauagu agacacaggu      300

auaggcauga cgaaagccga uuuaauaaac aaccucggaa ccauugcaaa aagcggaacc      360

aaggcauuca uggaagcucu acaagcagga gcggacauca gcaugauagg ccaguucgga      420

guggguuucu auucagcaua ccucguagca gaaaaaguaa ccgucauaac gaagcacaac      480

gacgaugaac aauaugcaug ggaaucaucc gccggaggaa guuucacagu ccgaacugac      540

acaggugaac ccaugggaag agguacuaaa guaauccuuc aucugaaaga agaucaaacc      600

gaauaccucg aagaacgacg aauaaaagaa auuguaaaaa agcauucaca auucaucgga      660

uacccuauaa cacucuucgu agaaaaagaa agggauaaag aaguaagcga ugaugaagca      720

gaagaaaagg aagacaaaga agaagaaaaa gaaaaagaag aaaaagaauc agaagauaaa      780

ccagaaauag aagacguagg auccgacgaa gaagaagaaa aaaaagacgg ugacaaaaaa      840

aaaaaaaaaa agauaaaaga aaaauacaua gaccaagaag aauuaaauaa aaccaaaccg      900

auauggacga gaaaucccga cgacauaacc aacgaagaau acggagaauu cuauaaaagc      960

cugaccaacg acugggaaga ccaucuggca gucaaacacu ucaguguaga aggacaauua     1020

gaauucagag cacuacuauu uguaccgaga cgagcaccau ucgacuuauu cgaaaauaga     1080

aaaaaaaaaa acaacauaaa auuguacgua agaagggucu ucauaaugga caauugugaa     1140

gaacuaauac ccgaauaucu aaacuucauu agaggcguug uagacucaga agaccuucca     1200

cucaauauau caagagaaau guuacaacaa aguaaaauac ugaagguaau aaggaaaaau     1260

uuaguaaaaa aaugcuugga acuauucaca gaacuagcag aagacaaaga aaacuacaaa     1320

aaauuuuaug aacaauucuc aaaaaacaua aaguuaggaa uucacgaaga uagccaaaau     1380

agaaagaaac uaucugaauu guuacgauau uauacauccg caucagguga cgaaauggug     1440

ucguuaaaag auuacugcac acgaaugaaa gaaaaccaaa aacauauaua uuacauaaca     1500

ggagaaacaa aagaucaagu agcaaacagc gcauucgucg aacgacugag aaagcacgga     1560

uuagaaguaa uauacaugau agaaccaaua gaugaauauu guguacaaca auuaaaagaa     1620

uucgaaggaa aaacucucgu aucaguaaca aaggaaggac uugaacuacc agaagaugaa     1680

gaagaaaaaa aaaaacaaga agaaaaaaag acaaaauuug aaaaccucug caaaauaaug     1740

aaagacauac uggaaaaaaa aguagaaaaa guaguagucu caaacagacu agugaccuca     1800

ccuuguugua uagucacaag cacauaugga uggaccgcaa acauggaaag aauaaugaaa     1860

gcacaagcau uaagagauaa cucaacaaug gguuacaugg cagcuaaaaa acaucucgaa     1920

auaaauccag aucauucuau aauagaaacu cuuagacaaa aagcagaagc agauaaaaac     1980

gacaagagug uaaaagacuu agucauacua uuauacgaaa cggcacuacu cagcagugga     2040

uuuaguuuag aagauccaca aacacacgcg aacaggaucu acagaaugau uaaacuagga     2100

uuaggaaucg augaagauga cccaacagca gacgacacau cagcagcagu aacagaagaa     2160

augccaccac uagaagggga cgaugacacu agccgaaugg aagaaguaga cuaaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  2556
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt13)

<400>  2556
gggagaaagc uuaccaugga cagcucaaaa cuagacucag gaaaaggacu acacauaaac       60

cuaguaccaa acaaacaaaa ccaaacacua acaauaguag acacaagaau aggaaugaca      120

aaaacagacc uaauaaacaa ccuaggaaca guaacaaaaa gcggaacaaa agcauucaug      180

gaagcacuac aagcagacgc agacauaagc augauaggac acuucggagu aggauucuac      240

ucagcauacc uaguagcaaa aaaaguaaca guaauaucaa aacacaacaa cgacgaacaa      300

uacacauggg aaucaagcgc aggaggaagc uucacaguaa gaacagacga auaaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  2557
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt13)

<400>  2557
gggagaaagc uuaccaugcc agaagaagua caucauggag aagaagaagu cgaaacguuu       60

gcuuuccaag cggaaauagc gcaacuaaug agccuaauaa uaaacacauu cuauaguaac      120

aaagaaaucu ucuugaggga auuaauuuca aacgccuccg augcauuaga caaaauaaga      180

uacgaaagcu uaacagaccc aucaaaauua gauagcggaa aagagcuaaa aaucgacaua      240

auaccuaacc cacaagaacg uacacugaca cuuguagaua caggaauagg aaugacaaaa      300

gcagaccuaa uaaacaaccu aggaacuaua gcuaaaucag gcacgaaagc cuucauggaa      360

gccuuacaag caggagcaga uauaucaaug auaggacaau uuggaguggg auucuacagc      420

gcauaccuag uagcagaaaa aguagucgua auaaccaaac auaaugacga cgaacaauac      480

gcaugggaaa gcucggcagg aggcagcuuu acaguaagag cagaucaugg cgaaccuaua      540

ggaaggggca ccaaagucau ccuacaucuc aaagaagauc aaacagaaua uuuagaagaa      600

agacgaguga aagagguagu caaaaagcau ucccaauuua uaggcuaucc aauaaccuua      660

uaccuagaaa aagaaagaga aaaagaaaua ucagacgacg aagccgaaga agaaaaagga      720

gaaaaagaag aagaagauaa agacgaugaa gaaaaaccaa aaauagaaga uguaggaagc      780

gaugaagaag acgacucagg aaaagacaaa aaaaaaaaga caaaaaaaau aaaagaaaaa      840

uauaucgauc aagaagaacu caacaaaaca aaacccauau ggacaagaaa uccagacgac      900

auaacacagg aagaauacgg agaauucuau aaaagccuua cgaaugacug ggaagaucau      960

cuagcaguaa aacacuucuc uguagaagga caacuagaau uccgagcccu acuauucaua     1020

ccaagacgcg caccauucga ccuauucgaa aauaaaaaaa aaaaaaacaa uauaaaauua     1080

uauguacgga gaguguucau aauggacagu ugcgaugaac uaauaccaga auacuuaaac     1140

uuuauaagag gagugguaga cucagaagac cuaccccuaa auauaagccg ggagauguua     1200

caacaaagca aaauauuaaa aguaaucagg aagaacauug uaaaaaaaug ucuggaacua     1260

uuuucagagu uagcagaaga uaaagaaaac uacaaaaaau ucuacgaagc auucucaaaa     1320

aauuuaaaau uagggauaca ugaagacagc acaaacagaa gaagacugag cgaacuacua     1380

agauaucaua caagucaaag uggagacgaa augacuucac uaagugaaua cguaucaaga     1440

augaaagaaa cacaaaaauc uauuuacuac auaacuggag aaucaaaaga acagguagca     1500

aacagcgcau uugucgaacg aguaagaaaa cgaggauucg aaguaguuua uaugacagaa     1560

ccuaucgaug aauauugcgu ccaacaacua aaagaauuug acggaaaauc acuugucagu     1620

guaacaaaag aaggacuaga acugcccgaa gacgaagaag aaaaaaaaaa aauggaagaa     1680

ucaaaggcua aauucgaaaa ucuaugcaaa uuaaugaaag aaauacucga caaaaaagua     1740

gaaaaaguaa ccauaagcaa ucgacuagua ucaaguccuu gcuguauagu cacaucaaca     1800

uauggaugga cagcgaauau ggaaaggaua augaaagccc aagcacuuag agacaauagu     1860

acaaugggau acaugauggc caaaaagcau cuagaaauaa auccugacca cccaaucgua     1920

gaaacacuaa gacaaaaagc agaagcagau aaaaacgaca aagcaguuaa agacuuaguu     1980

gucuuauuau ucgaaacagc acuacucuca aguggauucu cacuagaaga cccccaaaca     2040

cauaguaaca gaauauaccg aaugauuaaa uugggauuag gaaucgacga agacgaagug     2100

gcagccgaag aaccaaaugc cgcaguaccc gaugaaauac caccccuaga aggagacgaa     2160

gacgcaagua gaauggaaga aguagauuaa ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  2558
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt13)

<400>  2558
gggagaaagc uuaccaugag ggcauuaugg guucuaggac uauguugcgu acuacuaacg       60

uucggaucag uaagagcaga cgaugaagua gaugucgaug gcacaguaga ggaagaccua      120

ggaaaaucaa gagaaggaag ccguacagac gacgaaguag ugcaaagaga agaggaagca      180

auccaguugg auggacuaaa ugcaagucaa auaagagaac uaagagaaaa aucagaaaaa      240

uucgcauuuc aagcagaagu gaacagaaug augaaacuaa uaaucaauuc auuauauaaa      300

aacaaagaaa uauuccugag agaacuaaua agcaacgcaa gugaugcuuu agauaaaaua      360

cgacuaauua gcuuaacaga cgaaaaugca uuaagcggaa augaagaguu aacaguaaaa      420

auaaaaugug acaaagaaaa aaacuuacuc caugugacag acacaggagu aggaaugacc      480

cgcgaggaau ugguaaaaaa ucuaggaacg auagcuaaaa gcggaacaag ugaauuucuu      540

aauaaaauga cagaagcaca agaagacggc caaucaacaa gugaacuaau aggacaauuc      600

ggaguugguu uuuauagugc uuuuuuaguu gcugacaaag uaauagucac gucgaaacau      660

aauaacgaca cacaacacau cugggaaagu gacucgaaug aauuuucagu uauagcagau      720

ccaagaggaa auacgcuagg cagagggaca acaauaacau uaguacuuaa agaagaagca      780

ucagauuauu uagaauuaga uacaauaaaa aaccuaguaa aaaaauauag ucaauucaua      840

aauuucccca uauauguaug gaguaguaaa acagaaacgg uagaagaacc aauggaagaa      900

gaagaagcag cuaaagaaga aaaagaggaa agugacgaug aagcagcagu ugaagaagaa      960

gaagaagaaa aaaagccgaa aacuaaaaaa gucgaaaaaa cgguauggga cugggaacuu     1020

augaacgaua uaaagcccau auggcagaga ccgagcaaag aaguagaaga agaugaauau     1080

aaagcauuuu acaaaucauu uaguaaagaa ucagacgauc caauggcuua cauacauuuu     1140

acagccgagg gagaaguaac auucaaauca auuuuguuug uaccaacaag ugcucccaga     1200

gggcuauucg augaauacgg aucaaaaaaa agcgacuaua uaaaacucua uguaagaaga     1260

guauucauca ccgacgacuu ccacgauaug augccuaaau accuaaauuu cguaaaagga     1320

gucguagaua gugaugacuu accauuaaau guaagcagag aaacucucca acaacauaaa     1380

uuacuaaaag ugauacguaa aaaauuagua agaaaaacac ucgacaugau aaaaaaaaua     1440

gcggaugaua aauauaauga uacauucugg aaagaauucg gaacaaauau aaaacuuggc     1500

guaauagaag aucacucuaa uagaacaaga cuagcaaaac ucuuaagguu ccaaagcuca     1560

caucacccaa ccgauauaac uucauuagau caauauguag aaaggaugaa agaaaaacaa     1620

gauaaaauau auuuuauggc aggaucauca agaaaagaag cugaaaguag cccauucguc     1680

gaaagacuuc uuaaaaaagg guaugaaguu auauauuuga cagaaccagu agaugaauau     1740

uguauacagg cacuaccaga auucgauggu aaaagauucc aaaacguagc aaaagaaggc     1800

guaaaauucg acgaaaguga gaaaacuaag gaaucacgag aagcgguaga aaaagaauuc     1860

gagcccuuac ucaauuggau gaaagacaaa gcacuaaaag auaaaaucga aaaagcugug     1920

gucagucaaa gauuaacaga aucaccaugc gcauuaguug caagucaaua ugggugguca     1980

ggaaauaugg aaagaauaau gaaagcgcaa gcauaucaaa cuggaaagga uauaucgacu     2040

aacuacuacg caucgcaaaa gaaaacauuc gaaauaaauc cuagacaccc auuaauaaga     2100

gacaugcuac gaagaaucaa agaagaugaa gacgacaaga caguacuaga ucuagcagua     2160

guauuauuug aaacagcaac auuaagaucg gguuaccuuc uuccggauac aaaagcauac     2220

ggcgacagaa uagaaagaau gcucagacua ucacucaaca ucgacccaga ugcaaaagug     2280

gaagaggaac cagaagaaga accagaagaa acagcagaag auacgacaga agacacugaa     2340

caagaugagg acgaagaaau ggacguggga acugacgaag aagaagaaac ugcaaaagaa     2400

agcacugcug agaaagauga acuauaagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  2559
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt13)

<400>  2559
gggagaaagc uuaccauggc aagagaacua agagcucuau uacucugggg aagaagacua       60

cgaccauuau uaagagcccc ugcauuagca gcugucccag gcgguaaacc uauccuaugu      120

ccaagaagga cgacagcgca auuaggaccu agaagaaauc cagcuuggag cuuacaagca      180

gguagauuau uuaguacaca aacagcagaa gauaaagaag aaccucuaca uagcauaauc      240

aguaguacag aaucuguaca aggaaguaca aguaaacacg aauuucaagc cgaaacaaag      300

aaacuccuug acaucguagc uagaagucua uauucagaaa aagaaguauu caucagggaa      360

uuaauuucaa augcaucaga ugccuuagaa aaacuaagac acaaacuggu auccgaugga      420

caagcccuac cagaaaugga gauacauuua caaacaaacg cagaaaaagg uaccaucaca      480

auccaggaua cagguauagg caugacucaa gaagaacuug uuucuaaccu aggaacuaua      540

gcaagaucug gcaguaaagc auuccuagau gcuuuacaaa accaagcaga agcaucuuca      600

aaaauaauag gacaauuugg uguaggauuc uauagugcau uuaugguggc ugaucgugua      660

gaaguuuauu cacggucagc agcuccagga ucauuaggau accaauggcu aucugauggu      720

ucaggagucu ucgagauugc agaagcaucc ggaguaagaa caggcacaaa aaucauaaua      780

caccuaaaau cugauugcaa agaauuuucu agcgaagcaa gaguaagaga uguagucaca      840

aaauacucca acuucgucuc auucccacua uacuuaaaug gcagacgaau gaauacucua      900

caagcuauau ggaugaugga uccaaaagau guccgggaau ggcaacauga agaguucuau      960

agauacguug cucaagcuca cgacaaacca cgauauacac uucauuacaa aaccgaugca     1020

ccacuuaaua uaagaucaau auuuuaugua ccagacauga aaccaucuau guucgaugua     1080

uccagagaau uaggaucauc uguagcauua uacucaagaa aaguguuaau acaaacuaaa     1140

gcaacagaua ucuuaccaaa auggcuucga uucauaagag gaguuguaga uucagaagac     1200

aucccacuaa acuuaucgag agaauuacua caagaaucag cacuuauuag aaaacuaaga     1260

gauguccuac aacaaagauu aauaaaauuc uuuauagauc aaucaaagaa agaugcagaa     1320

aaauacgcaa aauucuucga agacuaugga cuauuuauga gggaaggcau aguaacugca     1380

acagaacaag aaguuaaaga agacauugca aaacuacuaa gauaugaaag uuccgcguua     1440

ccuucaggcc aacucacgag ucuaagcgaa uaugcaagcc gcaugcgugc aggaacuaga     1500

aacauauacu accuaugugc gccuaacagg caucucgcag aacauucccc uuacuacgaa     1560

gcaaugaaaa agaaagauac agaaguacuc uucugcuucg aacaauuuga ugaacucaca     1620

uuauuacauc uacgcgaguu cgacaaaaag aaauuaauau ccguagaaac agacaucguc     1680

guagaccacu auaaagaaga aaaauuugaa gacagauccc ccgcagcaga auguuuaagu     1740

gaaaaagaaa cagaagaauu aauggcaugg augagaaacg uacuuggcuc aagaguuacu     1800

aacguuaaag uaacucuacg acuagacaca cauccugcca ugguaacggu cuuagaaaug     1860

ggagcagcaa gacacuuccu uagaaugcaa caauuagcaa aaacccaaga agaaagagca     1920

caauuacuac aaccaacauu agaaaucaau ccuaggcaug cauuaauaaa gaaacuaaac     1980

cagcuuagag caagcgaacc cggucuugca caacuauuag uagaucaaau cuaugaaaac     2040

gccaugauag cagcaggucu aguugacgac cccagagcaa ugguagguag acuuaacgaa     2100

cuacucguca aagcauuaga aaggcauuaa ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  2560
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt13)

<400>  2560
gggagaaagc uuaccauggg aaaaauauca ucacuaccua cacaacuauu caaaugcugc       60

uucugcgacu uccuaaaagu aaaaaugcac acaaugucau ccucacaccu auucuaccua      120

gcacuaugcc uacuaacauu cacaucauca gcaacagccg gaccagaaac acuaugcgga      180

gcagaacuag uagacgcauu acaauucgua ugcggagaca gaggauucua cuucaacaaa      240

ccaacaggau acggaucauc aucaagaaga gcaccacaaa caggaauagu agacgaaugc      300

uguuucagau caugcgacuu aagaagacua gaaauguacu gcgcaccauu aaaaccagca      360

aaaagcgcaa gaucaguaag agcacaaaga cauacagaca ugccaaaaac acaaaaagaa      420

guacaccuaa aaaacgcauc aagaggauca gcaggaaaca aaaacuacag aauguaagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  2561
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt13)

<400>  2561
gggagaaagc uuaccauggg aauaccaaug ggaaaaucaa ugcuaguacu auuaacauuu       60

cuagccuucg caucauguug cauagcagca uacagaccaa gugaaacucu auguggagga      120

gaauuaguag auacacuaca auuuguaugu ggagauagag guuucuauuu caguagacca      180

gcaagcagag uaucaagaag aaguagagga auaguagaag aaugcuguuu cagaucaugu      240

gaccuagcac uacuagaaac auauugcgca acaccagcaa aaucagaaag agauguauca      300

acaccaccaa caguauuacc agauaacuuu ccaagauacc cuguaggaaa auuuuuccaa      360

uacgauacau ggaaacaauc aacacaaaga cuaagaagag gacuaccagc acuacuaaga      420

gcaagaagag gacacguacu agcaaaagaa cuagaagcau uuagagaagc aaaaagacau      480

agaccauuaa uagcauuacc aacacaagau ccagcacacg gaggagcacc accagaaaug      540

gcaucaaaca gaaaauaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  2562
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt13)

<400>  2562
gggagaaagc uuaccaugaa cucauuuuca acaucagcau ucggaccagu agcauucuca       60

cuaggauuac uacuaguacu accagcagca uucccagccc caguaccacc cggagaagac      120

uccaaagacg uagccgcccc acacagacaa ccacuaacau cauccgaaag aauagauaaa      180

caaauaagau acauacuaga cggaaucuca gcacuaagaa aagaaacaug caacaaauca      240

aacaugugcg aaucaucaaa agaagcacua gcagaaaaca auuuaaaccu accaaaaaug      300

gcagaaaaag acggcugcuu ccaaucagga uucaaugaag aaaccugccu aguaaaaaua      360

auaacaggau uacucgaauu cgaaguauac uuagaauacc uacaaaacag auucgaauca      420

ucagaagaac aagcaagagc aguacaaaug agcacaaaag uacucauaca auuccuacaa      480

aaaaaagcaa aaaaucuaga cgcaauaaca acaccagacc caacaacaaa cgcaucacua      540

cuaacaaaac uacaagcaca aaaccaaugg cuacaagaca ugacaacuca ccuaauacuc      600

agauccuuca aagaauuucu acaauccuca cuaagagcac uaagacaaau guaaggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  2563
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt13)

<400>  2563
gggagaaagc uuaccaugcc auuacuaugg uuaagagguu uucuauuagc aucaugcugg       60

auaauaguaa gaucaagucc aacaccagga agugaagguc auagugcagc accugacugu      120

ccuaguugcg cauuagcagc auuaccaaaa gacguaccaa acagccagcc agaaauggua      180

gaagcaguaa aaaaacauau auuaaauaug cuacaucuaa aaaaaaggcc agacguaaca      240

caaccaguac caaaagcggc uuuauuaaau gcaauaagaa aauuacaugu agguaaagua      300

ggagaaaacg guuacguaga aauagaggau gacauaggcc gaagagcaga aaugaaugaa      360

cuaauggaac aaacaaguga aauaauaaca uuugcagaau caggaacagc aagaaaaacg      420

cuacacuucg aaauaagcaa agaaggaagc gaucuuagug ugguagaaag agcagaagua      480

ugguuauucc ugaagguacc caaagccaau cgaacgagaa caaaaguaac aauaagauua      540

uuucaacaac aaaaacaucc acaagguuca cuagauacag gagaggaagc cgaagaagua      600

gguuuaaaag gagaaagauc ugaauuauua uuguccgaaa aaguaguaga ugccagaaaa      660

aguaccuggc auguauuucc agugaguuca ucaauacaaa gauuacuaga ucaagguaaa      720

ucaucacuag auguaagaau agcaugugaa caaugucaag aaaguggagc uaguuuagua      780

cuauuaggaa agaaaaaaaa aaaggaggaa gaaggagaag gaaaaaaaaa aggaggagga      840

gaaggaggag cgggagcaga ugaagaaaaa gaacaaaguc auagaccauu cuuaauguua      900

caagcaagac aaagcgaaga ucauccacac agaagaagac gacgaggacu agaaugcgau      960

ggaaaaguca auauauguug uaaaaaacaa uuuuuuguau cauuuaaaga cauaggaugg     1020

aacgauugga uaauagcgcc aucaggauau cacgcuaacu auugugaagg agaaugucca     1080

agccauauag caggaacgag uggaagcuca uuaucauuuc acagcacggu aauaaaccau     1140

uauagaauga gaggacauag cccauuugca aauuuaaaau cauguugugu accuacaaaa     1200

cuacguccaa ugagcaugcu auauuacgac gacggacaaa auauuauaaa gaaagauauc     1260

caaaauauga uaguagaaga gugcggaugu agcuaaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  2564
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt13)

<400>  2564
gggagaaagc uuaccaugga uggauuacca gggagagcau uaggagcagc augucuauua       60

uuauuagcag cagguugguu aggcccagaa gcauggggau cuccaacacc accaccaaca      120

ccagcagcac ccccaccacc accaccacca ggaaguccag gaggaagcca agauacaugu      180

acaagcugug guggauuuag aagaccagaa gaauuaggaa gaguagaugg agacuuuuua      240

gaagccguaa aaagacacau acuuucaaga uuacaaauga gaggaaggcc aaauauaaca      300

caugcaguac caaaggcagc aaugguuaca gcauuaagaa aauuacacgc aggaaaagua      360

agagaagaug guagaguaga aauaccacau uuagacgggc acgcaucacc aggugcagau      420

gggcaagaaa gaguaaguga gauaauuagc uuugcagaaa cagauggauu agcaucauca      480

agaguacgau uauauuucuu uauaaguaac gaaggaaauc aaaaucuauu cguagugcaa      540

gcaucacuau gguuauauuu aaaauuauug ccauauguac uagaaaaagg aagcagaaga      600

aagguaagag uuaaaguuua uuuucaagaa caaggucaug gagaucgaug gaauauggua      660

gaaaaacgag uagauuuaaa aagaucagga uggcauacau uuccacuaac agaagcaaua      720

caagcauuau ucgaaagagg cgaaagaaga cugaauuuag acgugcaaug ugacucaugc      780

caagaauuag cagugguucc agucuuugua gacccaggag aagaaagcca uagaccauuu      840

guaguaguac aagcaagacu aggagauagu agacauagaa uaagaaaaag agguuuagaa      900

ugugacggaa gaacaaauuu auguugcaga caacaauucu uuauugauuu uagguuaaua      960

gguuggaaug auuggauaau agcaccaaca ggauauuaug gaaauuauug ugaaggaagc     1020

uguccagcau auuuagcugg uguaccaggu ucagcuagua guuuucacac agcaguaguc     1080

aaucaauauc guaugcgagg auuaaauccu gguacuguaa auagcuguug uauaccaaca     1140

aaacuaagua caaugucaau guuauauuuu gaugaugaau auaauauagu uaaaagagau     1200

guuccaaaua ugauaguaga agaaugugga ugcgcuuaag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  2565
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt13)

<400>  2565
gggagaaagc uuaccauggc auuacgaguc uuacuuuuaa cagcauuaac ucugugccac       60

ggauuuaauc uugauacaga aaaugcaaug acauuucaag aaaacgcacg aggauuuggc      120

cagucgguag uacaguuaca ggguagcagg guuguugucg gugccccaca agaaauagua      180

gcagccaauc aaagagguuc acuauaccaa ugugauuacu cuacaggaag uugugagccc      240

auaagauuac aaguacccgu cgaagcaguc aauauguccc uaggacuaag uuuagcagca      300

acaacuagcc caccacaauu acuagcuugc ggcccaaccg uacaccagac auguucugaa      360

aauaccuaug ucaaagguuu augcuucuua uucgguagua auuuaagaca gcaaccacaa      420

aaauuuccug aagcacuacg cggauguccu caagaagacu ccgacauagc auuucuaaua      480

gacggaagug gcaguauaau accccaugac uuuaggagaa ugaaagaauu uguguccaca      540

guaauggaac aacuaaagaa aucuaagaca cuuuucucau uaaugcaaua uagugaagaa      600

uuuagaauac auuucaccuu caaagaauuu caaaacaacc cgaauccaag aucccuaguu      660

aaaccaauaa cccaguuacu aggaagaaca cauacugcca caggcauucg aaaaguagua      720

cgagaacuau uuaacauuac uaauggagcu agaaagaacg cuuucaaaau ucuaguaguu      780

auaacugaug gagagaaauu cggagacccu cuuggauacg aagauguuau accagaagcc      840

gauagagaag gagucauaag auauguaaua ggaguaggcg augccuuccg aagcgaaaaa      900

uccagacagg aacuaaauac aauagcuagc aaaccaccga gggaccacgu uuuucaaguc      960

aauaauuuug aagcauuaaa aaccauucaa aaccaacuaa gggagaaaau auucgcuaua     1020

gaaggaacac aaaccggauc uaguaguagc uuugaacaug aaauguccca agaagguuuu     1080

ucugcugcga uaacuucaaa uggcccacua cuaucaacag ucgguaguua ugauugggcc     1140

ggaggaguau uccuuuauac aaguaaagaa aaaucaacau ucauaaauau gacaagagua     1200

gacucugaua ugaaugaugc cuauuuagga uacgcagcag caaucauacu acgcaacaga     1260

guccaaucac ucguacuagg ugcccccaga uaccaacaua ucggucuggu cgcuauguuu     1320

cgucaaaaua cagguaugug ggaaaguaau gcaaauguaa aagguacuca aauaggcgca     1380

uauuuuggug cuucauuaug cagcguugac guggauucga acgguaguac agacuuagug     1440

uuaauaggcg caccccacua cuacgaacaa acaagaggug ggcagguauc aguaugcccu     1500

cuacccagag gccgugccag auggcaaugu gacgcaguac uauauggaga acaagggcaa     1560

ccauggggua gauuuggggc ugcauugaca guuuuaggag acguaaaugg agauaaacua     1620

acggauguug cuauaggagc cccuggugag gaagauaaua gaggagcggu auaccuauuu     1680

cauggaacau cuggaagugg aauuucaccu agucacucac aaaggauagc aggauccaag     1740

cucuccccac gauuacaaua uuuuggacag agccuaucgg gaggucaaga ucuaacuaug     1800

gaugguuugg uggaucucac cguaggcgcu caaggucaug ugcuacuauu acgaucacaa     1860

ccuguacuua gaguaaaagc cauaauggag uucaacccaa gagaaguagc ucguaaugua     1920

uucgaaugca acgaucaagu uguaaaaggc aaagaagcag gagaagugcg ugucugucuu     1980

cauguucaga aaagcacacg ugaucgauua agagagggcc aaauucaauc uguaguuaca     2040

uacgacuuag ccuuagacuc cggacgacca cacucucgcg cagucuuuaa ugaaacgaaa     2100

aacucaacac gaaggcaaac acaaguacua ggauuaacuc aaacaugcga aacccuuaaa     2160

cuacaauuac cuaacuguau cgaagaccca guaucuccaa ucguauugag acuaaauuuu     2220

uccuuaguag gcacaccacu uagugcuuuu ggaaaucuaa gaccggucuu agcagaagau     2280

gcucaaagau uauuuaccgc acuguuccca uucgagaaaa acuguggaaa cgauaauaua     2340

ugccaagacg acuuaucuau uacauucuca uucaugucgu uagauugucu aguaguagga     2400

ggacccagag aauuuaaugu aaccgucaca guucgaaaug acggagaaga cucauauaga     2460

acccaaguaa cauucuucuu uccguuagau cucagcuauc ggaaaguauc aacauuacaa     2520

aaccaacgaa gccaacgauc auggaggcuc gcaugugaaa gcgcuuccag uacggaagua     2580

aguggagcac ucaaaucuac aucuugcucu auuaaccacc caauauuucc ggaaaacagu     2640

gaggucacuu uuaauaucac cuucgacgua gauagcaaag ccaguuuagg aaauaaacuu     2700

cuucucaagg caaacguaac uucugaaaau aauaugccaa gaaccaacaa aacagaguuc     2760

caacuagaau uaccagucaa auacgcagua uauaugguag uaacaaguca uggaguuucc     2820

acgaaauacc uaaacuuuac ugcaucagaa aacacaagca gaguaaugca acaucaauac     2880

caaguaucaa auuuaggaca acgaaguuua ccaauaucgu uaguuuuccu ggucccaguc     2940

agauugaauc aaacaguaau cugggauaga ccacaaguaa cauuuucaga aaaucucuca     3000

ucaaccuguc auaccaagga aagauuaccu ucacauucag auuuucuagc agaacuacgc     3060

aaagcuccag uaguuaauug cucaaucgca guaugucaaa gaauacaaug ugacauccca     3120

uucuuuggca uucaagaaga auuuaacgcu acauuaaaag gaaaucuuag uuuugauugg     3180

uacaucaaaa ccagucauaa ccauuuacua auagucucua cugcugaaau acuauuuaau     3240

gauucuguau uuacucuauu accaggacaa ggagcuuuug uucgaucaca aacagaaacu     3300

aaaguagaac cauucgaagu cccaaaucca uuaccauuaa ucguggguuc uucuguaggc     3360

ggcuuauuac uuuuagcauu aauaacugcu gccuuguaua aauuaggauu uuucaaaagg     3420

caauauaaag auaugauguc ugaaggaggu ccacccggag ccgaaccaca auaaggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  2566
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt13)

<400>  2566
gggagaaagc uuaccauguu cucccucaaa acacuaccau ucuuacuacu acuccaugua       60

caaauaucca aagcauuccc uguaucauca aaagaaaaaa acacaaaaac aguacaagac      120

uaccuagaaa aauucuacca auuaccuuca aaccaauacc aaucaacaag aaaaaacgga      180

acaaacguua uaguagaaaa acuaaaagaa augcaacguu ucuuugguuu aaauguaaca      240

gguaaaccaa acgaagaaac auuagacaug augaaaaaac caagaugugg aguaccagac      300

uccggcggau uuauguuaac accaggaaau ccaaaauggg aaagaacaaa uuuaacuuac      360

cgaauaagaa acuacacacc ucaauuaagc gaagcagaag uagaaagagc aauaaaagau      420

gccuucgaac uaugguccgu agcaucaccu cuaauuuuca caagaauauc acaaggagaa      480

gcagacauca acauagcuuu uuaucaaaga gaucacggag acaauucacc auuugaugga      540

ccaaacggaa uccuagcaca ugcauuucaa cccggucaag gaauaggagg agacgcacac      600

uucgaugccg aagaaacaug gaccaacacu ucagcaaacu acaaccuauu ucuaguagca      660

gcacaugaau ucggccacuc auuaggacuc gcucauuccu cagacccugg agcccuaaug      720

uaucccaacu augcauucag agaaacauca aacuauucac uaccucaaga cgacauagau      780

ggaauucaag cuaucuacgg auuaucauca aacccaauuc aaccaacagg accaucaaca      840

cccaaaccuu gugacccauc ccuaacauuu gacgcuauaa caacacuaag aggagaaaua      900

uuauucuuca aagacagaua cuuuuggaga agacacccuc aacuacaaag aguugaaaug      960

aacuuuauau cauuauucug gccaucacua ccaacaggaa uacaagcagc auacgaagac     1020

uucgauagag acuuaauauu ccuuuucaaa ggaaaccaau acugggcccu aaguggauac     1080

gacauauuac aagguuaucc uaaagacaua ucaaacuacg gauuuccauc uucaguacaa     1140

gcaauagacg cagcagucuu cuauagauca aaaacauacu uuuucguaaa cgaccaauuc     1200

uggagauaug acaaccaacg acaauuuaug gaaccaggau auccaaaauc aauaucagga     1260

gcauucccug gaauagaauc caaaguagac gcaguauuuc aacaagaaca cuucuuccau     1320

guuuuuucag gaccaagaua cuacgcuuuu gacuuaauag cacaaagagu aacaagagua     1380

gcaagaggaa acaaauggcu aaacugccga uauggauaag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2567
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt13)

<400>  2567
gggagaaagc uuaccauguc auuauggcaa ccauuaguuu ugguacuuuu aguauuagga       60

uguuguuuug cugcaccacg ucaaagacaa aguacauuag uccuauuucc aggcgauuua      120

agaacaaauu uaacagacag acaacuugca gaagaauauc uauauagaua ugguuauaca      180

agaguagcug aaaugagagg ugaaucaaaa ucucuaggac cagcauuauu acuacuacaa      240

aaacaguuau cacuaccaga aaccggggaa cuagacucag cuacacuuaa agcaaugaga      300

acuccacggu guggaguccc agaucucggu cgguuucaaa cauuugaagg agaccuuaaa      360

uggcaucauc acaauauaac auauuggaua cagaauuauu cagaagaccu accaagagcg      420

guuauagacg acgcauucgc ccgagcauuu gcacuaugga gugcuguaac accauugacu      480

uuuacaaggg uauauagucg agaugcagau aucguaauac aauuuggugu agcagagcau      540

ggggauggau acccuuuuga cgguaaagac ggacuucuag cacaugcauu uccaccagga      600

ccuggaauac aaggagaugc ccauuuugau gacgacgaac uauggagucu uggaaaagga      660

gucguaguac cuacaagauu ugguaaugcu gauggugcag caugucauuu uccuuuuaua      720

uuugaaggac gaucuuacuc ugcaugcacu acagauggac guucagaugg auuaccaugg      780

uguucuacua cagccaauua ugauacagau gauagauuug guuuuugucc uucagaacga      840

uuauauacgc aagauggaaa ugcagaugga aaaccuuguc aauucccauu uauauuucaa      900

ggacaaucau auucagcaug uacaacagau ggacgaagcg auggauaucg auggugugca      960

acaacagcua acuacgacag agauaaauua uuugguuuuu guccaacucg cgcugacuca     1020

acagucaugg gugguaauag cgcuggugaa uuauguguau uuccauuuac uuuccuuggc     1080

aaagaauacu caacaugcac aucggaagga agaggagaug gacgauuaug gugugcaacu     1140

acuaguaauu ucgacaguga caaaaaaugg ggauuuuguc cggaccaagg guauucacuu     1200

uucuuaguug cagcacacga auucggucau gcacuuggcc uagaccauuc aucaguaccu     1260

gaagcucuua uguacccaau guauagauuu acagaaggac cuccacucca uaaagacgau     1320

gucaacggca uacgccaucu auauggucca cguccagagc cugaaccaag gccucccaca     1380

acaacaacac cacaaccuac ugcuccaccu acaguaugcc cgacuggccc accaacagua     1440

cauccaucug aaagaccaac ggccggacca acgggaccuc cuucagcggg uccaacagga     1500

ccaccaacag caggccccag cacugccacu acaguaccau uaucaccugu ggacgaugcu     1560

uguaauguua auauauuuga ugcaauagcu gaaauuggua aucaacugua uuuauuuaaa     1620

gauggaaaau auuggcgauu uagugaagga cgcggaucua gaccccaagg accauuucua     1680

auugccgaua aauggccagc ccuaccuaga aaauuagauu cuguauuuga agaaagauua     1740

ucaaaaaaau uauuuuuuuu cucaggaaga caaguauggg uuuauacagg agcaucagua     1800

cuaggaccua gaagacuaga uaaacuaggu uuaggagccg acgucgcaca aguuacaggc     1860

gcccuaagau caggaagagg aaaaauguua uuauucagcg guagaagauu auggagauuu     1920

gaugugaaag cacaaauggu ugauccaaga ucagcuagcg aagucgaucg aauguuccca     1980

gguguaccau uggauacuca ugauguuuuu caauauagag aaaaagcaua uuuuugucaa     2040

gauagauuuu auuggcgugu uucaucuagg agugaauuaa accaagugga ucaaguagga     2100

uauguaacau acgauauacu acaaugucca gaagauuaag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  2568
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt13)

<400>  2568
gggagaaagc uuaccaugca cccaggagua uuagcagcau uccucuucuu aucauggaca       60

cacugccgag cauuaccauu accaucagga ggagacgaag acgaucuauc agaagaagac      120

cuucaauucg cagaaagaua cuuaagauca uacuaccacc caacaaacuu agcagguaua      180

cuaaaagaaa acgcagccuc uucaaugaca gaaagacuua gagaaaugca aucauucuuc      240

ggauuagaag uaacaggaaa auuagaugac aauacacuag auguaaugaa aaaaccuaga      300

ugcggaguuc cugacguagg agaauauaac gucuuuccaa gaacauuaaa augguccaaa      360

augaaccuaa cauauagaau aguaaacuau acaccagaua ugacccauuc agaagucgaa      420

aaagcauuca aaaaagcauu caaaguaugg ucagauguaa caccucuaaa cuucacaaga      480

cuacaugacg gaauagcaga caucaugaua agcuuuggaa uaaaagaaca cggagauuuc      540

uacccauucg acggaccauc uggauuauua gcccacgcau uucccccagg accaaauuau      600

ggaggagacg cacauuucga ugacgaugaa acauggacau caucaucaaa aggauacaac      660

cuauucuuag uagcagcaca cgaauucgga cacucuuuag gcuuagacca uucaaaagac      720

cccggagcac uaauguuccc aauauauaca uauacaggaa aaagccacuu cauguuacca      780

gacgaugacg uccaagguau acaaagucua uacggaccag gagaugaaga uccuaaccca      840

aaacauccaa aaaccccaga caaaugugau ccaucauuau cauuagaugc cauaacauca      900

uuacgaggag aaacaaugau uuucaaagac cguuucuucu ggcgucuuca cccacaacaa      960

gucgacgcag aacucuuuuu aacaaaaucg uuuuggccug aacuaccaaa cagaauagau     1020

gcagcauacg aacacccuag ucacgacuua auauuuauuu uucgaggacg aaaauucugg     1080

gcccuaaaug gauacgauau auuagaagga uacccuaaaa aaauaucuga acuaggauua     1140

ccaaaagaag uaaaaaaaau aucagccgca guccacuuug aagauacagg aaaaacacuu     1200

cuauuuucag gcaaucaagu cuggagauac gacgacacaa accacauaau ggacaaagac     1260

uaccccagau uaauagaaga agacuuccca ggcauaggug acaaaguaga cgcaguauac     1320

gaaaaaaacg gauauauaua uuucuucaac ggaccaauac aauuugaaua cucuauaugg     1380

ucaaacagaa uaguaagagu aaugccagca aacuccauuu uauggugcua aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  2569
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt13)

<400>  2569
gggagaaagc uuaccaugga aacaccaaac acaacagaag acuacgauac aaccacagaa       60

uuugauuaug gagacgcaac accaugucaa aaaguaaacg aaagagccuu uggcgcgcaa      120

cuacuacccc cauuauacuc acuagucuuc gucauaggac uaguagguaa uauacuagua      180

guacuaguau uaguccaaua caaaagauua aaaaauauga caucaauaua uuuacuaaac      240

uuagcaauau cagauuuacu auuccuauuc acauuaccau ucuggaucga cuacaaacua      300

aaagacgacu ggguauuugg agacgcaaug ugcaaaauac ucucaggauu cuacuacaca      360

ggccuauacu cugaaaucuu cuucauaaua cuacuaacaa uagauagaua ccuagcaaua      420

guucaugcag uauucgcauu aagagccaga accgucacau ucggagucau aacaucaaua      480

auaauauggg ccuuagcaau auuagcauca augccaggac uauacuuuuc uaaaacacaa      540

ugggaauuca cacaucauac augcucacuu cacuucccuc acgaaucccu aagagaaugg      600

aaacucuucc aagcauuaaa acucaaucuu uucggacuag uacuaccccu acucguaaug      660

aucauaugcu acacaggaau aauaaaaaua cuacuacgac gaccaaacga aaaaaaauca      720

aaagcaguaa gauuaauauu cguaauaaug aucaucuucu uccuuuuuug gaccccuuac      780

aaccucacaa uacuaauauc aguauuccaa gacuuuuuau ucacacacga augugaacaa      840

uccagacauc ucgacuuagc aguacaaguc accgaaguaa uagcauacac acacuguugc      900

guuaaccccg uaauauacgc uuuuguagga gaaagauucc gaaaauaucu aagacaacua      960

uuucacagac gaguugcagu acacuuaguc aaaugguuac cauuucuauc aguagauaga     1020

uuagaaagag ucucauccac aucaccauca accggagaac acgaauuauc agcaggauuc     1080

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  2570
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt13)

<400>  2570
gggagaaagc uuaccaugag aacacuagca ugccuacuau uacuaggaug cggauaccua       60

gcacauguac uagcugaaga agcagaaaua ccaagagaag uaauagaaag acuagcaaga      120

ucacaaauac acucaauaag agaccuacaa cgacuacuag aaauagacuc agucggaagu      180

gaagacucac ucgacacaag ucuaagagca cacggaguac acgcaacaaa acacguacca      240

gaaaaaagac cacuacccau aagaagaaaa agaagcauag aagaagcagu accagcagua      300

ugcaaaacac gaacaguaau auacgaaaua ccaagaucac aaguagaccc aacaucagca      360

aacuuccuaa uauggccccc augcguagaa guaaaaagau gcacaggaug cugcaacaca      420

ucaagcguaa aaugccaacc aagcagggua caccacagaa gcgucaaagu agcaaaagua      480

gaauacguaa gaaaaaaacc aaaacuaaaa gaaguacaag uaagacuaga agaacaccua      540

gaaugcgcau gugcaacaac aagccuaaau ccagauuaca gagaagaaga cacaggaaga      600

ccaagagaaa gcggaaaaaa aagaaaaaga aaaagacuaa aaccaacaua aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  2571
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt13)

<400>  2571
gggagaaagc uuaccaugaa cagaugcugg gcauuauucu uaucauuaug cuguuaccua       60

agauuaguau cagcagaagg agauccaaua ccagaagaac uauacgaaau gcuaagcgau      120

cacaguauaa gaagcuuuga cgaucuacaa agauuacuuc acggcgaucc aggagaagaa      180

gacggagcag aauuagaccu aaauaugaca agaucacacu caggaggaga auuagaauca      240

cuagcacgug gaagaagaag ccuaggaagu cuaacaauag cagaaccugc aaugauagca      300

gaauguaaaa cacgaacaga aguauucgaa auaucaagaa gauuaauaga uagaacaaau      360

gcaaauuucu uaguauggcc accaugugua gaaguacaaa gaugcagugg augcugcaau      420

aacagaaacg uacaauguag accaacacaa guacaauuaa gaccaguaca aguaagaaaa      480

auagaaauag uaagaaaaaa accaauauuu aaaaaagcaa cagucacauu agaggaccac      540

cucgcaugca aaugugaaac cguagcagca gcaagaccag uaacaagaag cccaggcgga      600

agccaagaac aaagagcaaa aacaccacaa acuagaguua caauaagaac aguaagagua      660

cgaaggcccc caaaaggaaa acauagaaaa uucaaacaca cacacgacaa aacagcacua      720

aaagaaacac uaggagcgua aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  2572
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt13)

<400>  2572
gggagaaagc uuaccauguc auuauuugga uuauuacuac uuacaucagc auuagcagga       60

caaagacaag guacacaagc agaaagcaau cuaucaagca aauuccaauu uucauccaau      120

aaagaacaaa auggaguaca agacccacaa cacgaaagaa uaauaaccgu cagcacaaac      180

ggcucaauac auaguccacg auucccacau acauauccaa gaaacaccgu acucgucugg      240

agauuaguag caguugaaga aaauguaugg auccaauuaa cauucgacga aagauuugga      300

uuagaagacc cugaagacga cauaugcaaa uacgacuuug uagaaguaga agaaccauca      360

gacggaacaa uauuaggacg auggugcgga ucagguacag uaccugguaa acaaaucuca      420

aaaggcaacc aaauaagaau aagauucgua agcgaugaau acuucccaag ugaaccagga      480

uucuguauac auuacaauau cgucaugcca caauucacag aagcaguauc accaucagua      540

cuaccaccau cagcucuacc auuagacuua cuaaauaacg cuauaacagc auuuucaaca      600

uuagaagacu uaauacgaua cuuagaacca gaaagauggc aacuagaccu agaagaccua      660

uacaggccaa cauggcaacu ucuaggaaaa gcauuuguau uuggaagaaa aucacgaguu      720

gucgaucuaa accuauuaac agaagaagua agacuuuacu caugcacacc aagaaacuuu      780

ucaguaucca uaagagaaga acuaaaaaga acagauacaa uauucuggcc aggaugccua      840

cuaguaaaaa gaugcggcgg aaauugcgca ugcugcuuac acaacuguaa cgaaugccaa      900

ugcguaccau caaaaguuac aaaaaaauac cacgaaguac uacaauuaag acccaaaacu      960

ggaguuagag gacuacauaa aucucuaaca gacguagcac uagaacauca cgaagaaugu     1020

gacugcguuu gccgaggaag cacaggaggc uaaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  2573
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt13)

<400>  2573
gggagaaagc uuaccaugca cagauuaaua uuuguauaca cacuaauaug ugcaaacuuc       60

ugcucaugca gagacacauc cgcaacucca caaucagcau caauaaaagc uuuaagaaac      120

gcaaaucuaa gaagagacga ucuauacaga agagacgaaa ccauacaagu aaaaggaaac      180

ggcuacguac aaagcccacg auucccuaac ucauacccaa gaaaucuauu auuaacaugg      240

cgacuacacu cccaagaaaa cacaagaaua caacuaguau ucgauaacca auucggauua      300

gaagaagcag aaaacgacau auguagauau gauuucguag aaguagaaga cauaucagaa      360

acaucaacua uaauacgagg aagauggugc ggacacaaag aaguaccacc acgaauaaaa      420

ucaagaacaa accaaauaaa aauaacuuuc aaaucagaug acuacuucgu ugcaaaaccc      480

ggauucaaaa uauauuauag ccuacuagaa gacuuccaac cagcagcagc uucagaaaca      540

aauugggaau cagucacaag cucaauauca ggaguaucau auaauagccc aucaguuaca      600

gacccaacac uaaucgccga cgcauuagac aaaaaaauag cagaauucga uacaguagaa      660

gaucuacuaa aauacuuuaa cccugaauca uggcaagaag aucuagaaaa cauguaucua      720

gacacaccca gauacagagg aagaagcuac cacgacagaa aaucaaaagu agacuuagac      780

agacuaaaug augacgcaaa aagauacuca ugcacaccaa gaaacuacag cguaaauaua      840

agagaagaac uaaaauuagc aaacguagua uucuucccaa gaugucuauu aguacaacgc      900

ugcggaggaa acuguggaug cggaacagua aacuggcgaa gcuguacaug caauuccgga      960

aaaacaguca aaaaauacca cgaaguacua caauucgaac ccggacauau aaaaagaaga     1020

gguagagcaa aaacaauggc acuaguagau auacaauuag accaccauga aagaugcgau     1080

uguauaugca gcucuagacc uccaagauaa ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  2574
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt13)

<400>  2574
gggagaaagc uuaccauggu cacccauuca aaauucccag cagcaggaau gucaagacca       60

uuagacacau cauuacgauu aaaaacauuc ucaucaaaau cagaauacca acuaguagua      120

aaugcaguaa gaaaacuaca agaaucagga uucuauuggu cagcaguaac aggaggagaa      180

gcaaauuuau uacuaucagc agaaccagca ggaacuuucc uaauacgaga cucaucagac      240

caacgacacu ucuuuacucu aucaguaaaa acacaaucag gaacaaaaaa ccucagaaua      300

caaugugaag gaggaucauu cucccuacaa ucagacccca gaucaacaca acccguacca      360

agauucgacu gcguacuaaa acuaguacac cacuacaugc caccacccgg agcaccaucc      420

uucccaucuc caccaacaga accaucaucu gaaguaccug aacaaccauc agcacaacca      480

cuaccuggau caccaccaag aagagcauac uacauauacu caggaggaga aaaaauacca      540

cuaguacuuu caagaccacu aucaucuaau guagcaacac uacaacacuu augccgaaaa      600

acaguaaacg gccaccuaga cucauacgaa aaagucacac aacuaccagg accaauaaga      660

gaauucuuag aucaauacga cgcaccacua uaaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  2575
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt13)

<400>  2575
gggagaaagc uuaccauggu accaucagca ggacaauuag cauuauuugc acuaggaaua       60

guacuagcag caugucaagc auuagaaaac ucaacaucac cacuaucagc agacccacca      120

guagcagcag caguaguauc acauuuuaau gauugcccag acucacacac acaauucugc      180

uuucacggaa cauguagauu ucuaguacaa gaagacaaac cagcaugugu augucauuca      240

ggauauguag gagcaagaug ugaacaugca gauuuauuag caguaguagc agcaucacaa      300

aaaaaacaag caauaacugc auuaguagua guaaguauag uagcauuagc aguauuaaua      360

auaacaugug uauuaauaca uugcugucaa guaagaaaac auugugaaug gugcagagca      420

uuaauaugua gacaugaaaa accuucagca uuacuaaaag gaagaacagc augcugucac      480

ucagaaacag uaguauaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  2576
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt13)

<400>  2576
gggagaaagc uuaccaugcc accaucaggu cuacgacuac uaccucucuu acuaccuuua       60

cuauggcucc ucguacuaac cccaggccga ccagcagcug gccuaucaac augcaaaaca      120

auagacaugg aauuagucaa aagaaaaaga auagaagcaa uuagaggaca aauacuauca      180

aaauuaagau uagccucccc accuucucaa ggagaaguac caccaggucc acuaccugaa      240

gcaguccuag cacuauacaa cucaacaaga gacagaguag caggagaauc cgcagaacca      300

gaacccgaac cagaagcaga cuauuaugca aaagaaguca ccagaguacu aaugguagaa      360

acacauaaug aaaucuacga uaaauuuaaa caaucaacac auucaauaua cauguuuuuc      420

aacacaagug aacuaagaga agcaguacca gaaccaguau uacuaucacg agccgaauua      480

agacuccuaa gacuuaaacu aaaaguagaa caacacguug aauuauacca aaaauacucu      540

aacaacucau ggagauacuu aucuaaucga cuacuagcac ccucagacuc accagaaugg      600

cucucauucg acguaaccgg aguaguacga caauggcuau cccguggcgg ugaaauagaa      660

ggauucagac uauccgcaca cugcucuugc gacucaagag acaauacauu acaaguagau      720

auaaacggau ucacaacagg aagaagagga gacuuagcua caauccacgg aaugaaccgc      780

cccuuccuac uauuaauggc aacuccucua gaaagagcac aacacuuaca auccucaaga      840

cacagaagag cacuagacac aaacuauugu uucucaagca cugaaaaaaa cugcugcguc      900

cgacaauuau acauagacuu ccgaaaagau cucggaugga aauggauaca cgaaccaaaa      960

ggauaccacg ccaacuucug ccucggucca uguccauaua ucuggucacu agauacacaa     1020

uacuccaaag uacuagcauu auauaaccaa cauaauccag gagcaucagc agcgccaugc     1080

ugcguaccac aagcauuaga accacuccca auaguauacu augucggaag aaaaccaaaa     1140

guagaacaac uaucaaacau gauagucaga ucaugcaaau guucuuaagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  2577
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt13)

<400>  2577
gggagaaagc uuaccaugca cuauugcgua cuuucagcau uucuaauauu acaccuagua       60

acagucgcuu uaaguuuaag cacaugcuca accuuagaca uggaccaauu uaugagaaaa      120

cgaauagaag caauaagagg acaaauauua uccaaacuaa aacuaacauc accacccgaa      180

gauuauccag aaccagaaga agucccacca gaaguaauau caauauauaa cagcacaaga      240

gaccuccuac aagaaaaagc aucaagaaga gcagcagcau gcgaacgaga aagaucagau      300

gaagaauauu acgcuaaaga aguauacaaa auagacaugc cccccuucuu uccaucagaa      360

aaugcaauac caccaaccuu uuacagaccc uauuuucgaa uaguaagauu cgauguauca      420

gccauggaaa aaaacgcauc aaaccuaguc aaagcggaau ucagaguauu ccgacuucaa      480

aacccaaaag cuagaguucc cgaacaacga aucgaacuau aucaaauacu aaaaucaaaa      540

gaccuaaccu cacccacaca aagauacaua gacucaaaag uaguaaaaac cagagcagag      600

ggcgaauggu uaucauucga cguaacagac gcaguacacg aauggcuaca ucacaaagac      660

cgaaaucucg gauucaaaau aucacuacac ugcccaugcu gcacauucgu cccaucaaac      720

aacuauauaa uaccaaauaa aucagaagaa cuugaagcaa gauuugcugg aauagacgga      780

acaaguacau acaccucugg agaccaaaaa acuauaaaau caacaagaaa aaaaaacucu      840

ggcaaaacac cucaccuacu auuaaugcua cuacccucau acagacuaga aucacaacaa      900

acaaaccgaa gaaaaaaaag agcacuagac gcagcauacu guuucagaaa cguacaagau      960

aacugcugcc ucagaccacu auauauagac uucaaaagag accuaggaug gaaauggaua     1020

caugaaccaa aaggcuacaa cgccaacuuc ugcgcaggag caugcccaua cuuaugguca     1080

ucugacacac agcacucaag aguacuauca cuauacaaca caauaaaucc agaagcuuca     1140

gcaagucccu gcugcguauc acaagacuua gaacccuuaa cuauauuaua uuauaucgga     1200

aaaacaccaa aaauagaaca acuaucaaac augauaguaa aaucauguaa auguaguuaa     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  2578
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt13)

<400>  2578
gggagaaagc uuaccaugaa aaugcaccuc caaagagccc ucgucguucu cgcacuacua       60

aacuucgcaa ccguaucacu aucccuauca acaugcacaa cccuagacuu cggacacaua      120

aaaaaaaaaa gaguagaagc aauccgaggc caaauuuuau caaaacuaag acuaacauca      180

ccaccagaac ccacagucau gacacacgua ccauaccaag uccuagcacu auacaacuca      240

acacgagaac uauuagaaga aaugcacgga gaaagagaag aaggauguac acaagaaaac      300

acugaaagug aauacuaugc aaaagaaaua cacaaauucg auaugauaca aggacuagca      360

gaacacaacg aacuagcagu augcccaaaa ggaauaacau caaaaguauu ucgauucaac      420

guaucaucag uagagaaaaa ucgaacaaac cuauuuagag ccgaauuuag aguccuaaga      480

guccccaauc caucaucaaa aagaaacgaa caacgcauag aacuauuuca aauacuacgc      540

ccagacgaac acauagcaaa acaaagauac auagguggaa aaaaccuccc aaccagagga      600

acagccgaau ggcuaucauu cgacguaaca gacaccguca gagaauggcu acuccgcaga      660

gaaucaaacu uaggucuaga aauaucaaua cacugcccau gccauacauu ucaaccaaau      720

ggagacauau uagaaaacau acaugaagua auggaaauca aauucaaagg aguagacaac      780

gaagacgacc acggacgagg cgaccucggc agacuaaaaa aacaaaaaga ucaccacaau      840

ccacaccuaa uccuaaugau gauacccccc cacagacuag acaacccagg acaaggagga      900

caacgaaaaa aaagagcacu cgacacaaau uauuguuucc gaaaucuaga agaaaacugc      960

ugcguccguc cacuuuacau agacuucaga caagaccuag gauggaaaug gguucacgaa     1020

ccaaaaggau auuaugccaa cuucugcuca ggacccugcc cauacuuaag aucagcagac     1080

acaacacacu cuacaguacu aggacuauac aacacacuaa acccagaagc cucagcauca     1140

cccugcugug ucccacaaga ccuagaaccu uuaaccauac uauacuacgu aggaagaacu     1200

ccuaaaguag aacaacuuuc aaauauggua guaaaaucau gcaaaugcuc auaaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2579
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt13)

<400>  2579
gggagaaagc uuaccauggc accaguagca guaugggcag cacuugcagu aggacucgaa       60

uuaugggcag cagcacaugc auuaccugca caaguugcau ucacacccua cgcacccgaa      120

ccaggcucaa ccuguagauu aagagaauau uacgaucaaa cagcucaaau gugcuguucu      180

aaaugcucac cuggccaaca ugcaaaagua uuuugcacua aaacaucuga uaccguaugu      240

gauucuugug aagacucaac auauacacaa cuauggaacu ggguuccaga augucuauca      300

ugcggaucaa gauguucauc agaccaaguu gaaacacaag cauguacucg ugaacaaaau      360

cgaauuugca cauguagacc aggaugguau ugcgcuuuau cgaaacaaga aggauguaga      420

cuaugcgcac cucuuagaaa augcagacca ggcuuuggag ucgcucgacc cggaacugaa      480

acaucagacg uaguaugcaa accuugugca ccagguacau ucucuaacac aacaaguuca      540

acagauauuu guagaccaca ccaaauaugu aacguaguug cuauaccagg aaacgcaucu      600

auggaugcag uauguacauc uacgucaccu accagaucaa uggcaccagg agcaguucac      660

uuaccacaac caguaucaac aagaagucaa cacacacaac caacaccuga acccucaacu      720

gcaccaagca cuucauuucu acuaccaaug ggucccucac caccugcuga aggaucaaca      780

ggagacuucg cauuaccugu cggacuuauc guaggaguua cagcauuagg acuauuaaua      840

aucgguguag uaaauugugu uauuaugaca caaguaaaaa aaaaacccuu auguuuacaa      900

agagaagcca aaguaccuca uuuaccagca gauaaagcca gaggaaccca agguccagaa      960

caacaacauu uauuaaucac agcucccuca ucaucaucau caucuuuaga aucaucagca     1020

agugcucuag auagaagagc ucccacaaga aaccaaccuc aagcaccagg ugucgaagca     1080

ucaggagcug gugaagcucg ugcuucuacg ggaucuucag auucaucacc cggaggacac     1140

ggaacacaag uaaauguaac augcauagua aaugucuguu ccaguucgga ucauucauca     1200

caauguucau cacaagcauc aucuacuaug ggagauacag auaguucacc aucagaaucc     1260

ccaaaagacg aacaaguacc auuuucaaaa gaagaaugcg cauuuagauc acaauuagaa     1320

acaccagaaa cauuauuagg aucaacugaa gaaaaaccac uaccacuagg cguaccagau     1380

gcaggaauga aacccucaua aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  2580
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt13)

<400>  2580
gggagaaagc uuaccaugcc aguaaugaga uuauuuccau guuucuuaca auuauuagca       60

ggauuagcau uaccagcagu accaccacaa caaugggcgu uaucagcagg aaauggaagu      120

agugaaguag aaguaguacc auuucaagaa guauggggaa gaucauauug uagagcacua      180

gaaagacuag uagauguagu aagugaauau ccaagcgaag uagaacauau guuuucacca      240

ucauguguaa guuuauuaag auguacggga ugcuguggag augaaaauuu acauugugua      300

ccaguagaaa cagcaaaugu aacaaugcaa uuauuaaaaa uaagaagugg agauagacca      360

ucauauguag aauuaacauu uagccaacau guaagaugug aauguagacc auuaagagaa      420

aaaaugaaac cagaaagaag aagaccaaaa ggaagaggaa aaagaagaag agaaaaacaa      480

agaccaacag auugucauuu auguggagau gcaguaccaa gaagauaagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  2581
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt13)

<400>  2581
gggagaaagc uuaccaugac agauagacaa acagauacag cgccaagucc aucauaccau       60

uuauuaccag gaagaagaag aacaguagau gcagcagcga guagaggaca aggaccagag      120

ccagcaccag gaggaggagu agaaggaguu ggagcaagag gaguagcgcu aaaauuauuu      180

guacaacuau uaggaugcag uagauucggu ggagcaguag uaagagcugg agaagcagaa      240

ccauccggug cagccagaag cgcaaguagu ggaagagaag aaccacaacc agaagaagga      300

gaagaagaag aagaaaaaga agaggaaaga ggaccacaau ggagacuugg cgcuagaaaa      360

ccugggagcu ggacaggaga agcagcugua ugcgcagaua gugcaccagc agcaagagca      420

ccacaagcau uagcaagagc aucaggacga ggaggaagag uagcaagaag gggagccgaa      480

gaaaguggac cuccacauag uccaaguaga agaggaucag caaguagagc ugggccagga      540

agggcaucug aaacaaugaa uuuuuuauua aguuggguac auuggaguuu agcuuuauug      600

cuauauuuac aucacgcaaa auggagucaa gcagcaccaa uggcagaagg agggggacaa      660

aaucaucacg aaguaguaaa auuuauggau guuuaucaaa ggaguuauug ucauccuaua      720

gaaacguuag uagauauauu ucaagaauac ccagaugaaa uagaguauau auuuaaaccg      780

aguuguguac cauuaaugag auguggagga uguuguaaug acgaaggacu agaaugugua      840

ccaacagaag aaagcaauau aacuaugcag auaaugagaa uaaaaccuca ucaaggacaa      900

cauauaggag aaaugaguuu uuugcaacac aauaagugcg aauguagacc aaaaaaagau      960

cgagcaagac aagaaaaaaa aagcguaaga gguaaaggua aaggacaaaa aagaaaaaga     1020

aaaaaaagua gauauaaaag cuggagugua uacguagggg caagauguug uuugaugcca     1080

uggagccucc caggaccuca uccgugugga ccauguucag agagaagaaa acaucuguuu     1140

guacaagauc cacaaacaug uaaaugcagu ugcaaaaaua cggauucaag auguaaagcg     1200

agacaauuag aauuaaauga aaggacaugu agaugcgaua agccgagaag auaaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  2582
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt13)

<400>  2582
gggagaaagc uuaccaugaa cuucuuacua ucauggguac auuggagcuu agcacuauua       60

cuauaccuac accacgcaaa auggucacaa gcagcaccaa uggcagaagg aggaggacaa      120

aaccaccaug aaguaguaaa auucauggau guauaccaaa gaucauacug ccacccaaua      180

gaaacacuag uagacauauu ccaagaauac ccagacgaaa uagaauacau auucaaacca      240

ucauguguac cauuaaugag augcggagga ugcugcaacg acgaaggacu agaaugugua      300

ccaacagaag aaaguaacau aacaaugcaa auaaugagaa uaaaaccaca ucaaggacaa      360

cacauaggag aaaugagcuu ccuacaacac aauaaaugcg aaugcagacc aaaaaaagac      420

agagcaagac aagaaaaaaa aaguguaaga ggaaaaggaa aaggacaaaa aagaaaaaga      480

aaaaaaucaa gauacaaauc auggucagua uacguaggag caagaugcug ccuaaugcca      540

uggucacuac caggaccaca cccaugcgga ccaugcucag aaagaagaaa acaccuauuc      600

guacaagacc cacaaaccug caaaugcagu ugcaaaaaca cagacagcag augcaaagca      660

agacaauuag aacuaaacga aagaacaugc agaugcgaua aaccacgaag auaaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  2583
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt13)

<400>  2583
gggagaaagc uuaccauguc accacuauua agaagauuau uacuagcagc auuacuacaa       60

uuagcacccg cacaagcacc uguaucacaa ccagaugcac caggacauca aagaaaagua      120

guaucaugga uagacguaua cacaagagca acaugucaac caagagaagu aguaguacca      180

uuaacaguag aacuaauggg aacagucgca aaacaacuag uaccaucaug cguaacagua      240

caaagaugcg gaggcuguug uccagacgau ggauuagaau guguuccaac aggacaacau      300

caaguaagaa ugcaaauacu aaugauaaga uacccaucau cucaacuagg agaaaugucc      360

uuagaagaac auagucaaug cgaaugcaga ccaaaaaaaa aagauucagc aguaaaacca      420

gaccgagcag caacaccaca ucauagacca caaccacgau caguaccagg cugggacuca      480

gccccaggag caccaucacc agcagauaua acccauccca caccugcacc aggaccaucu      540

gcacaugcag caccuucaac aacaucagca uuaacaccag gaccagcagc agcagccgca      600

gacgcagcug caucaucagu agcaaaagga ggagcauaag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  2584
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt13)

<400>  2584
gggagaaagc uuaccaugca ccucuuagga uucuucucag uagcuugcuc auuauuagcc       60

gccgccuuau uaccaggacc aagagaagca ccagcagcag ccgcagcauu ugaaucagga      120

uuagacuuaa gugaugcuga accagacgca ggagaagcua cagcauaugc caguaaagac      180

uuagaagaac aauuaagauc aguaaguucc guagacgaau uaaugacagu acucuaucca      240

gaauacugga aaauguauaa augucaacua agaaaaggcg gauggcaaca uaauagggaa      300

caagcaaauc uaaauucaag aacagaagaa acuauaaaau ucgcagccgc acacuauaac      360

acggaaauac uaaaaaguau agauaacgaa uggagaaaaa cacaaugcau gccaagagaa      420

guaugcauag auguaggaaa agaauuugga guagcaacaa acacauuuuu caaaccacca      480

uguguaagcg uauacagaug uggcgguugc ugcaauagcg aaggauuaca auguaugaac      540

acuagcacuu cauacuuauc aaaaacacua uuugaaauua caguaccauu aagucaagga      600

ccuaaaccag uaacgauaag uuuugcaaac cacacaucau guagauguau gucaaaacua      660

gauguauaua gacaaguaca cucaauaaua agaagaucac uaccagcaac acuuccacaa      720

ugccaagcag caaauaaaac auguccaaca aacuauaugu ggaacaacca cauaugcaga      780

ugucuagcac aagaagauuu cauguuuagu ucagacgcag gagacgacag cacagaugga      840

uuucaugaca uaugcggacc caacaaagaa uuagacgaag aaacuuguca augcguaugu      900

agagcaggac uacgaccagc aucaugugga ccacauaaag aauuagacag aaacaguugc      960

caaugcguau gcaaaaauaa acuauuccca ucacaaugug gagcaaaucg agaauuugau     1020

gaaaacacau gucaaugugu augcaaaaga acaugcccaa gaaaucaacc auuaaaucca     1080

gguaaaugcg caugugaaug uacagaauca ccacaaaaau gccuauuaaa aggaaagaaa     1140

uuucaccauc aaacaugcag uuguuauaga agaccaugua caaauagaca aaaagccugu     1200

gaaccaggau ucuccuacuc agaagaagua uguagaugug uaccaaguua cuggaaaaga     1260

ccacaaaugu cauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  2585
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt13)

<400>  2585
gggagaaagc uuaccaugua ccgagaaugg guaguaguaa acguauucau gaugcuuuac       60

guacaacuag uacaaggauc aucaaaugaa cacggaccag uaaaaagauc aagccaauca      120

acauuagaaa gaucagaaca acaaauacga gcagcaucau cacucgaaga acuccuaaga      180

auaacacacu ccgaagacug gaaacuaugg cgaugcagac uaagauuaaa aucauucaca      240

ucaauggauu cacgcuccgc aucccacaga ucaacaagau uugccgccac auuuuacgac      300

auagaaacau uaaaagucau cgacgaagaa uggcaacgaa cacaaugcuc accuagagaa      360

acaugcguag aaguagcauc agaacuaggu aaauccacaa auaccuuuuu uaaaccaccu      420

ugcguaaacg uauucagaug cggaggcugu ugcaacgaag aaucacuaau uuguaugaac      480

acaucuacau ccuacauauc aaaacaacua uucgaaauau caguaccacu aacaagcgua      540

cccgaacuag uccccguaaa aguagcaaac cacacaggau gcaaaugccu accaacagca      600

ccaagacauc cauacuccau aauacgaaga ucaauacaaa uaccagaaga agacagaugc      660

ucacacucaa aaaaacuaug cccuauagau augcuauggg acagcaacaa augcaaaugc      720

guacuacaag aagaaaaccc ucuagcagga accgaagacc acagccaucu acaagaacca      780

gcauuaugcg guccacauau gauguucgac gaagacagau gcgaaugcgu augcaaaaca      840

ccaugcccca aagaccuuau acaacacccu aaaaacugua gcugcuuuga augcaaagaa      900

ucacuagaaa caugcugcca aaaacacaaa uuauuucacc cagacacaug cucaugcgaa      960

gacagaugcc cauuccacac cagaccaugc gcauccggua aaacagcaug ugcaaaacac     1020

ugcagauucc ccaaagaaaa aagagcagcc caaggaccac acucaagaaa aaauccauaa     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  2586
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (wt)

<400>  2586
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

cggacgagac cggguucgag cacucaggac uguggguuuc ugugcuggcu ggucuucugc      120

ugggagccug ccaggcacac cccaucccug acuccagucc ucuccugcaa uucgggggcc      180

aaguccggca gcgguaccuc uacacagaug augcccagca gacagaagcc caccuggaga      240

ucagggagga ugggacggug gggggcgcug cugaccagag ccccgaaagu cuccugcagc      300

ugaaagccuu gaagccggga guuauucaaa ucuugggagu caagacaucc agguuccugu      360

gccagcggcc agauggggcc cuguauggau cgcuccacuu ugacccugag gccugcagcu      420

uccgggagcu gcuucuugag gacggauaca auguuuacca guccgaagcc cacggccucc      480

cgcugcaccu gccagggaac aaguccccac accgggaccc ugcaccccga ggaccagcuc      540

gcuuccugcc acuaccaggc cugccccccg cacucccgga gccacccgga auccuggccc      600

cccagccccc cgaugugggc uccucggacc cucugagcau ggugggaccu ucccagggcc      660

gaagccccag cuacgcuucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  2587
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (wt)

<400>  2587
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

cggacgagac cggguucgag cacucaggac uguggguuuc ugugcuggcu ggucuucugc      120

ugggagccug ccaggcacac cccaucccug acuccagucc ucuccugcaa uucgggggcc      180

aaguccggca gcgguaccuc uacacagaug augcccagca gacagaagcc caccuggaga      240

ucagggagga ugggacggug gggggcgcug cugaccagag ccccgaaagu cuccugcagc      300

ugaaagccuu gaagccggga guuauucaaa ucuugggagu caagacaucc agguuccugu      360

gccagcggcc agauggggcc cuguauggau cgcuccacuu ugacccugag gccugcagcu      420

uccgggagcu gcuucuugag gacggauaca auguuuacca guccgaagcc cacggccucc      480

cgcugcaccu cccagggaac aaguccccac accgggaccc ugcaccccga ggaccagcuc      540

gcuuccugcc acuaccaggc cugccccccg cacucccgga gccacccgga auccuggccc      600

cccagccccc cgaugugggc uccucggacc cucugagcau ggugggaccu ucccagggcc      660

gaagccccag cuacgcuucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  2588
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (wt)

<400>  2588
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuuuccucc acugcugcug cugcuguucu gggguguggu gucucacagc uucccagcga      120

cucuagaaac acaagagcaa gauguggacu uaguccagaa auaccuggaa aaauacuaca      180

accugaagaa ugaugggagg caaguugaaa agcggagaaa uaguggccca gugguugaaa      240

aauugaagca aaugcaggaa uucuuugggc ugaaagugac ugggaaacca gaugcugaaa      300

cccugaaggu gaugaagcag cccagaugug gagugccuga uguggcucag uuuguccuca      360

cugaggggaa cccucgcugg gagcaaacac aucugaccua caggauugaa aauuacacgc      420

cagauuugcc aagagcagau guggaccaug ccauugagaa agccuuccaa cucuggagua      480

augucacacc ucugacauuc accaaggucu cugaggguca agcagacauc augauaucuu      540

uugucagggg agaucaucgg gacaacucuc cuuuugaugg accuggagga aaucuugcuc      600

augcuuuuca accaggccca gguauuggag gggaugcuca uuuugaugaa gaugaaaggu      660

ggaccaacaa uuucagagag uacaacuuac aucguguugc agcucaugaa cucggccauu      720

cucuuggacu cucccauucu acugauaucg gggcuuugau guacccuagc uacaccuuca      780

guggugaugu ucagcuagcu caggaugaca uugauggcau ccaagccaua uauggacguu      840

cccaaaaucc uguccagccc aucggcccac aaaccccaaa agcgugugac aguaagcuaa      900

ccuuugaugc uauaacuacg auucggggag aagugauguu cuuuaaagac agauucuaca      960

ugcgcacaaa ucccuucuac ccggaaguug agcucaauuu cauuucuguu uucuggccac     1020

aacugccaaa ugggcuugaa gcugcuuacg aauuugccga cagagaugaa guccgguuuu     1080

ucaaagggaa uaaguacugg gcuguucagg gacagaaugu gcuacacgga uaccccaagg     1140

acaucuacag cuccuuuggc uucccuagaa cugugaagca uaucgaugcu gcucuuucug     1200

aggaaaacac uggaaaaacc uacuucuuug uugcuaacaa auacuggagg uaugaugaau     1260

auaaacgauc uauggaucca gguuauccca aaaugauagc acaugacuuu ccuggaauug     1320

gccacaaagu ugaugcaguu uucaugaaag auggauuuuu cuauuucuuu cauggaacaa     1380

gacaauacaa auuugauccu aaaacgaaga gaauuuugac ucuccagaaa gcuaauagcu     1440

gguucaacug caggaaaaau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  2589
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (wt)

<400>  2589
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuuuccucc acugcugcug cugcuguucu gggguguggu gucucacagc uucccagcga      120

cucuagaaac acaagagcaa gauguggacu uaguccagaa auaccuggaa aaauacuaca      180

accugaagaa ugaugggagg caaguugaaa agcggagaaa uaguggccca gugguugaaa      240

aauugaagca aaugcaggag uucuuugggc ugaaagugac ugggaaacca gaugcugaaa      300

cccugaaggu gaugaagcag cccagaugug gagugccuga uguggcucag uuuguccuca      360

cugaggggaa cccucgcugg gagcaaacac aucugaccua caggauugaa aauuacacgc      420

cagauuugcc aagagcagau guggaccaug ccauugagaa agccuuccaa cucuggagua      480

augucacacc ucugacauuc accaaggucu cugaggguca agcagacauc augauaucuu      540

uugucagggg agaucaucgg gacaacucuc cuuuugaugg accuggagga aaucuugcuc      600

augcuuuuca accaggccca gguauuggag gggaugcuca uuuugaugaa gaugaaaggu      660

ggaccaacaa uuucagagag uacaacuuac aucguguugc agcucaugaa cucggccauu      720

cucuuggacu cucccauucu acugauaucg gggcuuugau guacccuagc uacaccuuca      780

guggugaugu ucagcuagcu caggaugaca uugauggcau ccaagccaua uauggacguu      840

cccaaaaucc uguccagccc aucggcccac aaaccccaaa agcgugugac aguaagcuaa      900

ccuuugaugc uauaacuacg auucggggag aagugauguu cuuuaaagac agauucuaca      960

ugcgcacaaa ucccuucuac ccggaaguug agcucaauuu cauuucuguu uucuggccac     1020

aacugccaaa ugggcuugaa gcugcuuacg aauuugccga cagagaugaa guccgguuuu     1080

ucaaagggaa uaaguacugg gcuguucagg gacagaaugu gcuacacgga uaccccaagg     1140

acaucuacag cuccuuuggc uucccuagaa cugugaagca uaucgaugcu gcucuuucug     1200

aggaaaacac uggaaaaacc uacuucuuug uugcuaacaa auacuggagg uaugaugaau     1260

auaaacgauc uauggaucca gguuauccca aaaugauagc acaugacuuu ccuggaauug     1320

gccacaaagu ugaugcaguu uucaugaaag auggauuuuu cuauuucuuu cauggaacaa     1380

gacaauacaa auuugauccu aaaacgaaga gaauuuugac ucuccagaaa gcuaauagcu     1440

gguucaacug caggaaaaau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  2590
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (wt)

<400>  2590
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuuuccucc acugcugcug cugcuguucu gggguguggu gucucacagc uuuguccuca      120

cugaggggaa cccucgcugg gagcaaacac aucugaccua caggauugaa aauuacacgc      180

cagauuugcc aagagcagau guggaccaug ccauugagaa agccuuccaa cucuggagua      240

augucacacc ucugacauuc accaaggucu cugaggguca agcagacauc augauaucuu      300

uugucagggg agaucaucgg gacaacucuc cuuuugaugg accuggagga aaucuugcuc      360

augcuuuuca accaggccca gguauuggag gggaugcuca uuuugaugaa gaugaaaggu      420

ggaccaacaa uuucagagag uacaacuuac aucguguugc agcucaugaa cucggccauu      480

cucuuggacu cucccauucu acugauaucg gggcuuugau guacccuagc uacaccuuca      540

guggugaugu ucagcuagcu caggaugaca uugauggcau ccaagccaua uauggacguu      600

cccaaaaucc uguccagccc aucggcccac aaaccccaaa agcgugugac aguaagcuaa      660

ccuuugaugc uauaacuacg auucggggag aagugauguu cuuuaaagac agauucuaca      720

ugcgcacaaa ucccuucuac ccggaaguug agcucaauuu cauuucuguu uucuggccac      780

aacugccaaa ugggcuugaa gcugcuuacg aauuugccga cagagaugaa guccgguuuu      840

ucaaagggaa uaaguacugg gcuguucagg gacagaaugu gcuacacgga uaccccaagg      900

acaucuacag cuccuuuggc uucccuagaa cugugaagca uaucgaugcu gcucuuucug      960

aggaaaacac uggaaaaacc uacuucuuug uugcuaacaa auacuggagg uaugaugaau     1020

auaaacgauc uauggaucca gguuauccca aaaugauagc acaugacuuu ccuggaauug     1080

gccacaaagu ugaugcaguu uucaugaaag auggauuuuu cuauuucuuu cauggaacaa     1140

gacaauacaa auuugauccu aaaacgaaga gaauuuugac ucuccagaaa gcuaauagcu     1200

gguucaacug caggaaaaau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  2591
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (wt)

<400>  2591
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

aaaauauuuu aaagauucuu auggauaguu auucuaaaga aucuaaaauu caaacuguac      120

guaggguuac gaguguauca cuuuuagcgg uauaucuuac uaugaauacu ucaaguuuag      180

uuuuagcaaa accaauagaa aauacuaaug auacuaguau aaaaaaugug gagaaauuaa      240

gaaaugcucc aaaugaagag aauaguaaaa agguagaaga uaguaaaaau gauaagguag      300

aacaugugaa aaauauagaa gaggcaaagg uugagcaagu ugcacccgaa guaaaaucua      360

aaucaacuuu aagaagugcu ucuauagcga auacuaauuc ugagaaauau gauuuugagu      420

auuuaaaugg uuugagcuau acugaacuua caaauuuaau uaaaaauaua aaguggaauc      480

aaauuaaugg uuuauuuaau uauaguacag guucucaaaa guucuuugga gauaaaaauc      540

guguacaagc uauaauuaau gcuuuacaag aaaguggaag aacuuacacu gcaaaugaua      600

ugaaggguau agaaacuuuc acugagguuu uaagagcugg uuuuuauuua ggguacuaua      660

augaugguuu aucuuauuua aaugauagaa acuuccaaga uaaauguaua ccugcaauga      720

uugcaauuca aaaaaauccu aacuuuaagc uaggaacugc aguucaagau gaaguuauaa      780

cuucuuuagg aaaacuaaua ggaaaugcuu cugcuaaugc ugaaguaguu aauaauugug      840

uaccaguucu aaaacaauuu agagaaaacu uaaaucaaua ugcuccugau uacguuaaag      900

gaacagcugu aaaugaauua auuaaaggua uugaauucga uuuuucuggu gcugcauaug      960

aaaaagaugu uaagacaaug ccuugguaug gaaaaauuga uccauuuaua aaugaacuua     1020

aggccuuagg ucuauaugga aauauaacaa gugcaacuga gugggcaucu gauguuggaa     1080

uauacuauuu aaguaaauuc ggucuuuacu caacuaaccg aaaugacaua guacagucac     1140

uugaaaaggc uguagauaug uauaaguaug guaaaauagc cuuuguagca auggagagaa     1200

uaacuuggga uuaugauggg auugguucua augguaaaaa gguggaucac gauaaguucu     1260

uagaugaugc ugaaaaacau uaucugccaa agacauauac uuuugauaau ggaaccuuua     1320

uuauaagagc aggggauaag guauccgaag aaaaaauaaa aaggcuauau ugggcaucaa     1380

gagaagugaa gucucaauuc cauagaguag uuggcaauga uaaagcuuua gaggugggaa     1440

augccgauga uguuuuaacu augaaaauau uuaauagccc agaagaauau aaauuuaaua     1500

ccaauauaaa ugguguaagc acugauaaug guggucuaua uauagaacca agagggacuu     1560

ucuacacuua ugagagaaca ccucaacaaa guauauuuag ucuugaagaa uuguuuagac     1620

augaauauac ucacuauuua caagcgagau aucuuguaga ugguuuaugg gggcaagguc     1680

cauuuuauga aaaaaauaga uuaacuuggu uugaugaagg uacagcugaa uucuuugcag     1740

gaucuacccg uacaucuggu guuuuaccaa gaaaaucaau auuaggauau uuggcuaagg     1800

auaaaguaga ucauagauac ucauuaaaga agacucuuaa uucaggguau gaugacagug     1860

auuggauguu cuauaauuau ggauuugcag uugcacauua ccuauaugaa aaagauaugc     1920

cuacauuuau uaagaugaau aaagcuauau ugaauacaga ugugaaaucu uaugaugaaa     1980

uaauaaaaaa auuaagugau gaugcaaaua aaaauacaga auaucaaaac cauauucaag     2040

aguuagcaga uaaauaucaa ggagcaggca uaccucuagu aucagaugau uacuuaaaag     2100

aucauggaua uaagaaagca ucugaaguau auucugaaau uucaaaagcu gcuucucuua     2160

caaacacuag uguaacagca gaaaaaucuc aauauuuuaa cacauucacu uuaagaggaa     2220

cuuauacagg ugaaacuucu aaaggugaau uuaaagauug ggaugaaaug aguaaaaaau     2280

uagauggaac uuuggagucc cuugcuaaaa auucuuggag uggauacaaa acuuuaacag     2340

cauacuuuac gaauuauaga guuacaagcg auaauaaagu ucaauaugau guaguuuucc     2400

augggguuuu aacagauaau gcggauauua guaacaauaa ggcuccaaua gcaaagguaa     2460

cuggaccaag cacuggugcu guaggaagaa auauugaauu uaguggaaaa gauaguaaag     2520

augaagaugg uaaaauagua ucauaugauu gggauuuugg cgauggugca acuaguagag     2580

gcaaaaauuc aguacaugcu uacaaaaaag caggaacaua uaauguuaca uuaaaaguaa     2640

cugacgauaa gggugcaaca gcuacagaaa gcuuuacuau agaaauaaag aacgaagaua     2700

caacaacacc uauaacuaaa gaaauggaac cuaaugauga uauaaaagag gcuaaugguc     2760

caauaguuga agguguuacu guaaaaggug auuuaaaugg uucugaugau gcugauaccu     2820

ucuauuuuga uguaaaagaa gauggugaug uuacaauuga acuuccuuau ucagggucau     2880

cuaauuucac augguuaguu uauaaagagg gagacgauca aaaccauauu gcaaguggua     2940

uagauaagaa uaacucaaaa guuggaacau uuaaaucuac aaaaggaaga cauuaugugu     3000

uuauauauaa acacgauucu gcuucaaaua uauccuauuc uuuaaacaua aaaggauuag     3060

guaacgagaa auugaaggaa aaagaaaaua augauucuuc ugauaaagcu acaguuauac     3120

caaauuucaa uaccacuaug caagguucac uuuuagguga ugauucaaga gauuauuauu     3180

cuuuugaggu uaaggaagaa ggcgaaguua auauagaacu agauaaaaag gaugaauuug     3240

guguaacaug gacacuacau ccagagucaa auauuaauga cagaauaacu uacggacaag     3300

uugaugguaa uaagguaucu aauaaaguua aauuaagacc aggaaaauau uaucuacuug     3360

uuuauaaaua cucaggauca ggaaacuaug aguuaagggu aaauaaauaa ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  2592
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (wt)

<400>  2592
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

aaaauauuuu aaagauucuu auggauaguu auucuaaaga aucuaaaauu caaacuguac      120

guaggguuac gaguguauca cuuuuagcgg uauaucuuac uaugaauacu ucaaguuuag      180

uuuuagcaaa accaauagaa aauacuaaug auacaaguau aaaaaaugug gagaaauuaa      240

gaaaugcucc aaaugaagag aauaguaaaa agguagaaga uaguaaaaau gauaagguag      300

aacaugugaa aaauauagaa gaggcaaagg uugagcaagu ugcacccgaa guaaaaucua      360

aaucaacuuu aagaagugcu ucuauagcga auacuaauuc ugagaaauau gauuuugagu      420

auuuaaaugg uuugagcuau acugaacuua caaauuuaau uaaaaauaua aaguggaauc      480

aaauuaaugg uuuauuuaau uauaguacag guucucaaaa guucuuugga gauaaaaauc      540

guguacaagc uauaauuaau gcuuuacaag aaaguggaag aacuuacacu gcaaaugaua      600

ugaaggguau agaaacuuuc acugagguuu uaagagcugg uuuuuauuua ggguacuaua      660

augaugguuu aucuuauuua aaugauagaa acuuccaaga uaaauguaua ccugcaauga      720

uugcaauuca aaaaaauccu aacuuuaagc uaggaacugc aguucaagau gaaguuauaa      780

cuucuuuagg aaaacuaaua ggaaaugcuu cugcuaaugc ugaaguaguu aauaauugug      840

uaccaguucu aaaacaauuu agagaaaacu uaaaucaaua ugcuccugau uacguuaaag      900

gaacagcugu aaaugaauua auuaaaggua uugaguucga uuuuucuggu gcugcauaug      960

aaaaagaugu uaagacaaug ccuugguaug gaaaaauuga uccauuuaua aaugaacuua     1020

aggccuuagg ucuauaugga aauauaacaa gugcaacuga gugggcaucu gauguuggaa     1080

uauacuauuu aaguaaauuc ggucuuuacu caacuaaccg aaaugacaua guacagucac     1140

uugaaaaggc uguagauaug uauaaguaug guaaaauagc cuuuguagca auggagagaa     1200

uaacuuggga uuaugauggg auugguucua augguaaaaa gguggaucac gauaaguucu     1260

uagaugaugc ugaaaaacau uaucugccaa agacauauac uuuugauaau ggaaccuuua     1320

uuauaagagc aggggauaag guauccgaag aaaaaauaaa aaggcuauau ugggcaucaa     1380

gagaagugaa gucucaauuc cauagaguag uuggcaauga uaaagcauua gaggugggaa     1440

augccgauga uguuuuaacu augaaaauau uuaauagccc agaagaauau aaauuuaaua     1500

ccaauauaaa ugguguaagc acugauaaug guggucuaua uauagaacca agagggacuu     1560

ucuacacuua ugagagaaca ccucaacaaa guauauuuag ucuugaagaa uuguuuagac     1620

augaauauac ucacuauuua caagcgagau aucuuguaga ugguuuaugg gggcaagguc     1680

cauuuuauga aaaaaauaga uuaacuuggu uugaugaagg uacagcugag uucuuugcag     1740

gaucuacccg uacaucuggu guuuuaccaa gaaaaucaau auuaggauau uuggcuaagg     1800

auaaaguaga ucauagauac ucauuaaaga agacucuuaa uucaggguau gaugacagug     1860

auuggauguu cuauaauuau ggauuugcag uugcacauua ccuauaugaa aaagauaugc     1920

cuacauuuau uaagaugaau aaagcuauau ugaauacaga ugugaaaucu uaugaugaaa     1980

uaauaaaaaa auuaagugau gaugcaaaua aaaauacaga auaucaaaac cauauucaag     2040

aguuagcaga uaaauaucaa ggagcaggca uaccucuagu aucagaugau uacuuaaaag     2100

aucauggaua uaagaaagca ucugaaguau auucugaaau uucaaaagcu gcuucucuua     2160

caaacacaag uguaacagca gaaaaaucuc aauauuuuaa cacauucacu uuaagaggaa     2220

cuuauacagg ugaaacuucu aaaggugaau uuaaagauug ggaugaaaug aguaaaaaau     2280

uagauggaac uuuggagucc cuugcuaaaa auucuuggag uggauacaaa acuuuaacag     2340

cauacuuuac gaauuauaga guuacaagcg auaauaaagu ucaauaugau guaguuuucc     2400

augggguuuu aacagauaau gcggauauua guaacaauaa ggcuccaaua gcaaagguaa     2460

cuggaccaag cacuggugcu guaggaagaa auauugaauu uaguggaaaa gauaguaaag     2520

augaagaugg uaaaauagua ucauaugauu gggauuuugg cgauggugca acaaguagag     2580

gcaaaaauuc aguacaugcu uacaaaaaag caggaacaua uaauguuaca uuaaaaguaa     2640

cugacgauaa gggugcaaca gcuacagaga gcuuuacuau agaaauaaag aacgaagaua     2700

caacaacacc uauaacuaaa gaaauggaac cuaaugauga uauaaaagag gcuaaugguc     2760

caauaguuga agguguuacu guaaaaggug auuuaaaugg uucugaugau gcugauaccu     2820

ucuauuuuga uguaaaagaa gauggugaug uuacaauuga acuuccuuau ucagggucau     2880

cuaauuucac augguuaguu uauaaagagg gagacgauca aaaccauauu gcaaguggua     2940

uagauaagaa uaacucaaaa guuggaacau uuaaaucuac aaaaggaaga cauuaugugu     3000

uuauauauaa acacgauucu gcuucaaaua uauccuauuc uuuaaacaua aaaggauuag     3060

guaacgagaa auugaaggaa aaagaaaaua augauucuuc ugauaaagcu acaguuauac     3120

caaauuucaa uaccacuaug caagguucac uuuuagguga ugauucaaga gauuauuauu     3180

cuuuugaggu uaaggaagaa ggcgaaguua auauagaacu agauaaaaag gaugaauuug     3240

guguaacaug gacacuacau ccagagucaa auauuaauga cagaauaacu uacggacaag     3300

uugaugguaa uaagguaucu aauaaaguua aauuaagacc aggaaaauau uaucuacuug     3360

uuuauaaaua cucaggauca ggaaacuaug aguuaagggu aaauaaauaa ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  2593
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (wt)

<400>  2593
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

ggguaaccuu uauuucccuu cuuuuucucu uuagcucggc uuauuccaua gcgaauacua      120

auucugagaa auaugauuuu gaguauuuaa augguuugag cuauacugaa cuuacaaauu      180

uaauuaaaaa uauaaagugg aaucaaauua augguuuauu uaauuauagu acagguucuc      240

aaaaguucuu uggagauaaa aaucguguac aagcuauaau uaaugcuuua caagaaagug      300

gaagaacuua cacugcaaau gauaugaagg guauagaaac uuucacugag guuuuaagag      360

cugguuuuua uuuaggguac uauaaugaug guuuaucuua uuuaaaugau agaaacuucc      420

aagauaaaug uauaccugca augauugcaa uucaaaaaaa uccuaacuuu aagcuaggaa      480

cugcaguuca agaugaaguu auaacuucuu uaggaaaacu aauaggaaau gcuucugcua      540

augcugaagu aguuaauaau uguguaccag uucuaaaaca auuuagagaa aacuuaaauc      600

aauaugcucc ugauuacguu aaaggaacag cuguaaauga auuaauuaaa gguauugaau      660

ucgauuuuuc uggugcugca uaugaaaaag auguuaagac aaugccuugg uauggaaaaa      720

uugauccauu uauaaaugaa cuuaaggccu uaggucuaua uggaaauaua acaagugcaa      780

cugagugggc aucugauguu ggaauauacu auuuaaguaa auucggucuu uacucaacua      840

accgaaauga cauaguacag ucacuugaaa aggcuguaga uauguauaag uaugguaaaa      900

uagccuuugu agcaauggag agaauaacuu gggauuauga ugggauuggu ucuaauggua      960

aaaaggugga ucacgauaag uucuuagaug augcugaaaa acauuaucug ccaaagacau     1020

auacuuuuga uaauggaacc uuuauuauaa gagcagggga uaagguaucc gaagaaaaaa     1080

uaaaaaggcu auauugggca ucaagagaag ugaagucuca auuccauaga guaguuggca     1140

augauaaagc uuuagaggug ggaaaugccg augauguuuu aacuaugaaa auauuuaaua     1200

gcccagaaga auauaaauuu aauaccaaua uaaauggugu aagcacugau aauggugguc     1260

uauauauaga accaagaggg acuuucuaca cuuaugagag aacaccucaa caaaguauau     1320

uuagucuuga agaauuguuu agacaugaau auacucacua uuuacaagcg agauaucuug     1380

uagaugguuu augggggcaa gguccauuuu augaaaaaaa uagauuaacu ugguuugaug     1440

aagguacagc ugaauucuuu gcaggaucua cccguacauc ugguguuuua ccaagaaaau     1500

caauauuagg auauuuggcu aaggauaaag uagaucauag auacucauua aagaagacuc     1560

uuaauucagg guaugaugac agugauugga uguucuauaa uuauggauuu gcaguugcac     1620

auuaccuaua ugaaaaagau augccuacau uuauuaagau gaauaaagcu auauugaaua     1680

cagaugugaa aucuuaugau gaaauaauaa aaaaauuaag ugaugaugca aauaaaaaua     1740

cagaauauca aaaccauauu caagaguuag cagauaaaua ucaaggagca ggcauaccuc     1800

uaguaucaga ugauuacuua aaagaucaug gauauaagaa agcaucugaa guauauucug     1860

aaauuucaaa agcugcuucu cuuacaaaca cuaguguaac agcagaaaaa ucucaauauu     1920

uuaacacauu cacuuuaaga ggaacuuaua caggugaaac uucuaaaggu gaauuuaaag     1980

auugggauga aaugaguaaa aaauuagaug gaacuuugga gucccuugcu aaaaauucuu     2040

ggaguggaua caaaacuuua acagcauacu uuacgaauua uagaguuaca agcgauaaua     2100

aaguucaaua ugauguaguu uuccaugggg uuuuaacaga uaaugcggau auuaguaaca     2160

auaaggcucc aauagcaaag guaacuggac caagcacugg ugcuguagga agaaauauug     2220

aauuuagugg aaaagauagu aaagaugaag augguaaaau aguaucauau gauugggauu     2280

uuggcgaugg ugcaacuagu agaggcaaaa auucaguaca ugcuuacaaa aaagcaggaa     2340

cauauaaugu uacauuaaaa guaacugacg auaagggugc aacagcuaca gaaagcuuua     2400

cuauagaaau aaagaacgaa gauacaacaa caccuauaac uaaagaaaug gaaccuaaug     2460

augauauaaa agaggcuaau gguccaauag uugaaggugu uacuguaaaa ggugauuuaa     2520

augguucuga ugaugcugau accuucuauu uugauguaaa agaagauggu gauguuacaa     2580

uugaacuucc uuauucaggg ucaucuaauu ucacaugguu aguuuauaaa gagggagacg     2640

aucaaaacca uauugcaagu gguauagaua agaauaacuc aaaaguugga acauuuaaau     2700

cuacaaaagg aagacauuau guguuuauau auaaacacga uucugcuuca aauauauccu     2760

auucuuuaaa cauaaaagga uuagguaacg agaaauugaa ggaaaaagaa aauaaugauu     2820

cuucugauaa agcuacaguu auaccaaauu ucaauaccac uaugcaaggu ucacuuuuag     2880

gugaugauuc aagagauuau uauucuuuug agguuaagga agaaggcgaa guuaauauag     2940

aacuagauaa aaaggaugaa uuugguguaa cauggacacu acauccagag ucaaauauua     3000

augacagaau aacuuacgga caaguugaug guaauaaggu aucuaauaaa guuaaauuaa     3060

gaccaggaaa auauuaucua cuuguuuaua aauacucagg aucaggaaac uaugaguuaa     3120

ggguaaauaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  2594
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (wt)

<400>  2594
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

ggguaaccuu uauuucccuu cuuuuucucu uuagcucggc uuauuccaua gcgaauacua      120

auucugagaa auaugauuuu gaguauuuaa augguuugag cuauacugaa cuuacaaauu      180

uaauuaaaaa uauaaagugg aaucaaauua augguuuauu uaauuauagu acagguucuc      240

aaaaguucuu uggagauaaa aaucguguac aagcuauaau uaaugcuuua caagaaagug      300

gaagaacuua cacugcaaau gauaugaagg guauagaaac uuucacugag guuuuaagag      360

cugguuuuua uuuaggguac uauaaugaug guuuaucuua uuuaaaugau agaaacuucc      420

aagauaaaug uauaccugca augauugcaa uucaaaaaaa uccuaacuuu aagcuaggaa      480

cugcaguuca agaugaaguu auaacuucuu uaggaaaacu aauaggaaau gcuucugcua      540

augcugaagu aguuaauaau uguguaccag uucuaaaaca auuuagagaa aacuuaaauc      600

aauaugcucc ugauuacguu aaaggaacag cuguaaauga auuaauuaaa gguauugagu      660

ucgauuuuuc uggugcugca uaugaaaaag auguuaagac aaugccuugg uauggaaaaa      720

uugauccauu uauaaaugaa cuuaaggccu uaggucuaua uggaaauaua acaagugcaa      780

cugagugggc aucugauguu ggaauauacu auuuaaguaa auucggucuu uacucaacua      840

accgaaauga cauaguacag ucacuugaaa aggcuguaga uauguauaag uaugguaaaa      900

uagccuuugu agcaauggag agaauaacuu gggauuauga ugggauuggu ucuaauggua      960

aaaaggugga ucacgauaag uucuuagaug augcugaaaa acauuaucug ccaaagacau     1020

auacuuuuga uaauggaacc uuuauuauaa gagcagggga uaagguaucc gaagaaaaaa     1080

uaaaaaggcu auauugggca ucaagagaag ugaagucuca auuccauaga guaguuggca     1140

augauaaagc auuagaggug ggaaaugccg augauguuuu aacuaugaaa auauuuaaua     1200

gcccagaaga auauaaauuu aauaccaaua uaaauggugu aagcacugau aauggugguc     1260

uauauauaga accaagaggg acuuucuaca cuuaugagag aacaccucaa caaaguauau     1320

uuagucuuga agaauuguuu agacaugaau auacucacua uuuacaagcg agauaucuug     1380

uagaugguuu augggggcaa gguccauuuu augaaaaaaa uagauuaacu ugguuugaug     1440

aagguacagc ugaguucuuu gcaggaucua cccguacauc ugguguuuua ccaagaaaau     1500

caauauuagg auauuuggcu aaggauaaag uagaucauag auacucauua aagaagacuc     1560

uuaauucagg guaugaugac agugauugga uguucuauaa uuauggauuu gcaguugcac     1620

auuaccuaua ugaaaaagau augccuacau uuauuaagau gaauaaagcu auauugaaua     1680

cagaugugaa aucuuaugau gaaauaauaa aaaaauuaag ugaugaugca aauaaaaaua     1740

cagaauauca aaaccauauu caagaguuag cagauaaaua ucaaggagca ggcauaccuc     1800

uaguaucaga ugauuacuua aaagaucaug gauauaagaa agcaucugaa guauauucug     1860

aaauuucaaa agcugcuucu cuuacaaaca caaguguaac agcagaaaaa ucucaauauu     1920

uuaacacauu cacuuuaaga ggaacuuaua caggugaaac uucuaaaggu gaauuuaaag     1980

auugggauga aaugaguaaa aaauuagaug gaacuuugga gucccuugcu aaaaauucuu     2040

ggaguggaua caaaacuuua acagcauacu uuacgaauua uagaguuaca agcgauaaua     2100

aaguucaaua ugauguaguu uuccaugggg uuuuaacaga uaaugcggau auuaguaaca     2160

auaaggcucc aauagcaaag guaacuggac caagcacugg ugcuguagga agaaauauug     2220

aauuuagugg aaaagauagu aaagaugaag augguaaaau aguaucauau gauugggauu     2280

uuggcgaugg ugcaacaagu agaggcaaaa auucaguaca ugcuuacaaa aaagcaggaa     2340

cauauaaugu uacauuaaaa guaacugacg auaagggugc aacagcuaca gagagcuuua     2400

cuauagaaau aaagaacgaa gauacaacaa caccuauaac uaaagaaaug gaaccuaaug     2460

augauauaaa agaggcuaau gguccaauag uugaaggugu uacuguaaaa ggugauuuaa     2520

augguucuga ugaugcugau accuucuauu uugauguaaa agaagauggu gauguuacaa     2580

uugaacuucc uuauucaggg ucaucuaauu ucacaugguu aguuuauaaa gagggagacg     2640

aucaaaacca uauugcaagu gguauagaua agaauaacuc aaaaguugga acauuuaaau     2700

cuacaaaagg aagacauuau guguuuauau auaaacacga uucugcuuca aauauauccu     2760

auucuuuaaa cauaaaagga uuagguaacg agaaauugaa ggaaaaagaa aauaaugauu     2820

cuucugauaa agcuacaguu auaccaaauu ucaauaccac uaugcaaggu ucacuuuuag     2880

gugaugauuc aagagauuau uauucuuuug agguuaagga agaaggcgaa guuaauauag     2940

aacuagauaa aaaggaugaa uuugguguaa cauggacacu acauccagag ucaaauauua     3000

augacagaau aacuuacgga caaguugaug guaauaaggu aucuaauaaa guuaaauuaa     3060

gaccaggaaa auauuaucua cuuguuuaua aauacucagg aucaggaaac uaugaguuaa     3120

ggguaaauaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  2595
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (wt)

<400>  2595
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

ggguaaccuu uauuucccuu cuuuuucucu uuagcucggc uuauuccaug aaaaaaaaua      120

uuuuaaagau ucuuauggau aguuauucua aagaaucuaa aauucaaacu guacguaggg      180

uuacgagugu aucacuuuua gcgguauauc uuacuaugaa uacuucaagu uuaguuuuag      240

caaaaccaau agaaaauacu aaugauacua guauaaaaaa uguggagaaa uuaagaaaug      300

cuccaaauga agagaauagu aaaaagguag aagauaguaa aaaugauaag guagaacaug      360

ugaaaaauau agaagaggca aagguugagc aaguugcacc cgaaguaaaa ucuaaaucaa      420

cuuuaagaag ugcuucuaga aggcggcgca agagaauagc gaauacuaau ucugagaaau      480

augauuuuga guauuuaaau gguuugagcu auacugaacu uacaaauuua auuaaaaaua      540

uaaaguggaa ucaaauuaau gguuuauuua auuauaguac agguucucaa aaguucuuug      600

gagauaaaaa ucguguacaa gcuauaauua augcuuuaca agaaagugga agaacuuaca      660

cugcaaauga uaugaagggu auagaaacuu ucacugaggu uuuaagagcu gguuuuuauu      720

uaggguacua uaaugauggu uuaucuuauu uaaaugauag aaacuuccaa gauaaaugua      780

uaccugcaau gauugcaauu caaaaaaauc cuaacuuuaa gcuaggaacu gcaguucaag      840

augaaguuau aacuucuuua ggaaaacuaa uaggaaaugc uucugcuaau gcugaaguag      900

uuaauaauug uguaccaguu cuaaaacaau uuagagaaaa cuuaaaucaa uaugcuccug      960

auuacguuaa aggaacagcu guaaaugaau uaauuaaagg uauugaauuc gauuuuucug     1020

gugcugcaua ugaaaaagau guuaagacaa ugccuuggua uggaaaaauu gauccauuua     1080

uaaaugaacu uaaggccuua ggucuauaug gaaauauaac aagugcaacu gagugggcau     1140

cugauguugg aauauacuau uuaaguaaau ucggucuuua cucaacuaac cgaaaugaca     1200

uaguacaguc acuugaaaag gcuguagaua uguauaagua ugguaaaaua gccuuuguag     1260

caauggagag aauaacuugg gauuaugaug ggauugguuc uaaugguaaa aagguggauc     1320

acgauaaguu cuuagaugau gcugaaaaac auuaucugcc aaagacauau acuuuugaua     1380

auggaaccuu uauuauaaga gcaggggaua agguauccga agaaaaaaua aaaaggcuau     1440

auugggcauc aagagaagug aagucucaau uccauagagu aguuggcaau gauaaagcuu     1500

uagagguggg aaaugccgau gauguuuuaa cuaugaaaau auuuaauagc ccagaagaau     1560

auaaauuuaa uaccaauaua aaugguguaa gcacugauaa ugguggucua uauauagaac     1620

caagagggac uuucuacacu uaugagagaa caccucaaca aaguauauuu agucuugaag     1680

aauuguuuag acaugaauau acucacuauu uacaagcgag auaucuugua gaugguuuau     1740

gggggcaagg uccauuuuau gaaaaaaaua gauuaacuug guuugaugaa gguacagcug     1800

aauucuuugc aggaucuacc cguacaucug guguuuuacc aagaaaauca auauuaggau     1860

auuuggcuaa ggauaaagua gaucauagau acucauuaaa gaagacucuu aauucagggu     1920

augaugacag ugauuggaug uucuauaauu auggauuugc aguugcacau uaccuauaug     1980

aaaaagauau gccuacauuu auuaagauga auaaagcuau auugaauaca gaugugaaau     2040

cuuaugauga aauaauaaaa aaauuaagug augaugcaaa uaaaaauaca gaauaucaaa     2100

accauauuca agaguuagca gauaaauauc aaggagcagg cauaccucua guaucagaug     2160

auuacuuaaa agaucaugga uauaagaaag caucugaagu auauucugaa auuucaaaag     2220

cugcuucucu uacaaacacu aguguaacag cagaaaaauc ucaauauuuu aacacauuca     2280

cuuuaagagg aacuuauaca ggugaaacuu cuaaagguga auuuaaagau ugggaugaaa     2340

ugaguaaaaa auuagaugga acuuuggagu cccuugcuaa aaauucuugg aguggauaca     2400

aaacuuuaac agcauacuuu acgaauuaua gaguuacaag cgauaauaaa guucaauaug     2460

auguaguuuu ccaugggguu uuaacagaua augcggauau uaguaacaau aaggcuccaa     2520

uagcaaaggu aacuggacca agcacuggug cuguaggaag aaauauugaa uuuaguggaa     2580

aagauaguaa agaugaagau gguaaaauag uaucauauga uugggauuuu ggcgauggug     2640

caacuaguag aggcaaaaau ucaguacaug cuuacaaaaa agcaggaaca uauaauguua     2700

cauuaaaagu aacugacgau aagggugcaa cagcuacaga aagcuuuacu auagaaauaa     2760

agaacgaaga uacaacaaca ccuauaacua aagaaaugga accuaaugau gauauaaaag     2820

aggcuaaugg uccaauaguu gaagguguua cuguaaaagg ugauuuaaau gguucugaug     2880

augcugauac cuucuauuuu gauguaaaag aagaugguga uguuacaauu gaacuuccuu     2940

auucaggguc aucuaauuuc acaugguuag uuuauaaaga gggagacgau caaaaccaua     3000

uugcaagugg uauagauaag aauaacucaa aaguuggaac auuuaaaucu acaaaaggaa     3060

gacauuaugu guuuauauau aaacacgauu cugcuucaaa uauauccuau ucuuuaaaca     3120

uaaaaggauu agguaacgag aaauugaagg aaaaagaaaa uaaugauucu ucugauaaag     3180

cuacaguuau accaaauuuc aauaccacua ugcaagguuc acuuuuaggu gaugauucaa     3240

gagauuauua uucuuuugag guuaaggaag aaggcgaagu uaauauagaa cuagauaaaa     3300

aggaugaauu ugguguaaca uggacacuac auccagaguc aaauauuaau gacagaauaa     3360

cuuacggaca aguugauggu aauaagguau cuaauaaagu uaaauuaaga ccaggaaaau     3420

auuaucuacu uguuuauaaa uacucaggau caggaaacua ugaguuaagg guaaauaaau     3480

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  2596
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (wt)

<400>  2596
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

ggguaaccuu uauuucccuu cuuuuucucu uuagcucggc uuauuccaug aaaaaaaaua      120

uuuuaaagau ucuuauggau aguuauucua aagaaucuaa aauucaaacu guacguaggg      180

uuacgagugu aucacuuuua gcgguauauc uuacuaugaa uacuucaagu uuaguuuuag      240

caaaaccaau agaaaauacu aaugauacaa guauaaaaaa uguggagaaa uuaagaaaug      300

cuccaaauga agagaauagu aaaaagguag aagauaguaa aaaugauaag guagaacaug      360

ugaaaaauau agaagaggca aagguugagc aaguugcacc cgaaguaaaa ucuaaaucaa      420

cuuuaagaag ugcuucuaga aggcggcgca agagaauagc gaauacuaau ucugagaaau      480

augauuuuga guauuuaaau gguuugagcu auacugaacu uacaaauuua auuaaaaaua      540

uaaaguggaa ucaaauuaau gguuuauuua auuauaguac agguucucaa aaguucuuug      600

gagauaaaaa ucguguacaa gcuauaauua augcuuuaca agaaagugga agaacuuaca      660

cugcaaauga uaugaagggu auagaaacuu ucacugaggu uuuaagagcu gguuuuuauu      720

uaggguacua uaaugauggu uuaucuuauu uaaaugauag aaacuuccaa gauaaaugua      780

uaccugcaau gauugcaauu caaaaaaauc cuaacuuuaa gcuaggaacu gcaguucaag      840

augaaguuau aacuucuuua ggaaaacuaa uaggaaaugc uucugcuaau gcugaaguag      900

uuaauaauug uguaccaguu cuaaaacaau uuagagaaaa cuuaaaucaa uaugcuccug      960

auuacguuaa aggaacagcu guaaaugaau uaauuaaagg uauugaguuc gauuuuucug     1020

gugcugcaua ugaaaaagau guuaagacaa ugccuuggua uggaaaaauu gauccauuua     1080

uaaaugaacu uaaggccuua ggucuauaug gaaauauaac aagugcaacu gagugggcau     1140

cugauguugg aauauacuau uuaaguaaau ucggucuuua cucaacuaac cgaaaugaca     1200

uaguacaguc acuugaaaag gcuguagaua uguauaagua ugguaaaaua gccuuuguag     1260

caauggagag aauaacuugg gauuaugaug ggauugguuc uaaugguaaa aagguggauc     1320

acgauaaguu cuuagaugau gcugaaaaac auuaucugcc aaagacauau acuuuugaua     1380

auggaaccuu uauuauaaga gcaggggaua agguauccga agaaaaaaua aaaaggcuau     1440

auugggcauc aagagaagug aagucucaau uccauagagu aguuggcaau gauaaagcau     1500

uagagguggg aaaugccgau gauguuuuaa cuaugaaaau auuuaauagc ccagaagaau     1560

auaaauuuaa uaccaauaua aaugguguaa gcacugauaa ugguggucua uauauagaac     1620

caagagggac uuucuacacu uaugagagaa caccucaaca aaguauauuu agucuugaag     1680

aauuguuuag acaugaauau acucacuauu uacaagcgag auaucuugua gaugguuuau     1740

gggggcaagg uccauuuuau gaaaaaaaua gauuaacuug guuugaugaa gguacagcug     1800

aguucuuugc aggaucuacc cguacaucug guguuuuacc aagaaaauca auauuaggau     1860

auuuggcuaa ggauaaagua gaucauagau acucauuaaa gaagacucuu aauucagggu     1920

augaugacag ugauuggaug uucuauaauu auggauuugc aguugcacau uaccuauaug     1980

aaaaagauau gccuacauuu auuaagauga auaaagcuau auugaauaca gaugugaaau     2040

cuuaugauga aauaauaaaa aaauuaagug augaugcaaa uaaaaauaca gaauaucaaa     2100

accauauuca agaguuagca gauaaauauc aaggagcagg cauaccucua guaucagaug     2160

auuacuuaaa agaucaugga uauaagaaag caucugaagu auauucugaa auuucaaaag     2220

cugcuucucu uacaaacaca aguguaacag cagaaaaauc ucaauauuuu aacacauuca     2280

cuuuaagagg aacuuauaca ggugaaacuu cuaaagguga auuuaaagau ugggaugaaa     2340

ugaguaaaaa auuagaugga acuuuggagu cccuugcuaa aaauucuugg aguggauaca     2400

aaacuuuaac agcauacuuu acgaauuaua gaguuacaag cgauaauaaa guucaauaug     2460

auguaguuuu ccaugggguu uuaacagaua augcggauau uaguaacaau aaggcuccaa     2520

uagcaaaggu aacuggacca agcacuggug cuguaggaag aaauauugaa uuuaguggaa     2580

aagauaguaa agaugaagau gguaaaauag uaucauauga uugggauuuu ggcgauggug     2640

caacaaguag aggcaaaaau ucaguacaug cuuacaaaaa agcaggaaca uauaauguua     2700

cauuaaaagu aacugacgau aagggugcaa cagcuacaga gagcuuuacu auagaaauaa     2760

agaacgaaga uacaacaaca ccuauaacua aagaaaugga accuaaugau gauauaaaag     2820

aggcuaaugg uccaauaguu gaagguguua cuguaaaagg ugauuuaaau gguucugaug     2880

augcugauac cuucuauuuu gauguaaaag aagaugguga uguuacaauu gaacuuccuu     2940

auucaggguc aucuaauuuc acaugguuag uuuauaaaga gggagacgau caaaaccaua     3000

uugcaagugg uauagauaag aauaacucaa aaguuggaac auuuaaaucu acaaaaggaa     3060

gacauuaugu guuuauauau aaacacgauu cugcuucaaa uauauccuau ucuuuaaaca     3120

uaaaaggauu agguaacgag aaauugaagg aaaaagaaaa uaaugauucu ucugauaaag     3180

cuacaguuau accaaauuuc aauaccacua ugcaagguuc acuuuuaggu gaugauucaa     3240

gagauuauua uucuuuugag guuaaggaag aaggcgaagu uaauauagaa cuagauaaaa     3300

aggaugaauu ugguguaaca uggacacuac auccagaguc aaauauuaau gacagaauaa     3360

cuuacggaca aguugauggu aauaagguau cuaauaaagu uaaauuaaga ccaggaaaau     3420

auuaucuacu uguuuauaaa uacucaggau caggaaacua ugaguuaagg guaaauaaau     3480

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  2597
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  2597
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaauu       60

uuuuaaaaau uauuuuaaau agggggaaga cuaugaaaag gaaauguuua ucuaaaaggc      120

uuauguuagc uauaacaaug gcuacaauau uuacagugaa caguacauua ccaauuuaug      180

cagcuguaga uaaaaauaau gcaacagcag cuguacaaaa ugaaaguaag agguauacag      240

uaucauauuu aaagacuuua aauuauuaug acuuaguaga uuugcuuguu aagacugaaa      300

uugagaauuu accagaccuu uuucaguaua guucagaugc aaaagaguuc uauggaaaua      360

aaacucguau gagcuuuauc auggaugaaa uugguagaag ggcaccucag uauacagaga      420

uagaucauaa agguauuccu acuuuaguag aaguuguaag agcuggauuu uacuuaggau      480

uccauaacaa ggaauugaau gaaauaaaca agaggucuuu uaaagaaagg guaauaccuu      540

cuauauuagc aauucaaaaa aauccuaauu uuaaacuagg uacugaaguu caagauaaaa      600

uaguaucugc aacaggacuu uuagcuggua augaaacagc gccuccagaa guuguaaaua      660

auuuuacacc aauacuucaa gacuguauaa agaauauaga cagauacgcu cuugaugauu      720

uaaagucaaa agcauuauuu aauguuuuag cugcaccuac cuaugauaua acugaguauu      780

uaagagcuac uaaagaaaaa ccagaaaaca cuccuuggua ugguaaaaua gauggguuua      840

uaaaugaacu uaaaaaguua gcucuuuaug gaaaaauaaa ugauaauaac ucuuggauaa      900

uagauaacgg uauauaucau auagcaccuu uagggaaguu acauagcaau aauaaaauag      960

gaauagaaac uuuaacagag guuaugaaag uuuauccuua uuuaaguaug caacauuuac     1020

aaucagcaga ucaaauuaag cgucauuaug auucaaaaga ugcugaagga aacaaaauac     1080

cuuuagauaa guuuaaaaag gaaggaaaag aaaaauacug uccaaaaacu uauacauuug     1140

augauggaaa aguaauaaua aaagcuggug cuagaguaga agaagaaaaa guuaaaagac     1200

uauacugggc aucaaaggaa guuaacucuc aauucuuuag aguauacgga auagacaaac     1260

cauuagaaga agguaaucca gaugauauau uaacaauggu uaucuacaac agucccgaag     1320

aauauaaacu caauaguguu cuauacggau augauacuaa uaaugguggu auguauauag     1380

agccagaagg aacuuucuuc accuaugaaa gagaagcuca agaaagcaca uacacauuag     1440

aagaauuauu uagacaugaa uauacacauu auuugcaagg aagauaugca guuccaggac     1500

aauggggaag aacaaaacuu uaugacaaug auagauuaac uugguaugaa gaagguggag     1560

cagaauuauu ugcagguucu acuagaacuu cuggaauauu accaagaaag aguauaguau     1620

caaauauuca uaauacaaca agaaauaaua gauauaagcu uucagacacu guacauucua     1680

aauauggugc uaguuuugaa uucuauaauu augcauguau guuuauggau uauauguaua     1740

auaaagauau ggguauauua aauaaacuaa augaucuugc aaaaaauaau gauguugaug     1800

gauaugauaa uuauauuaga gauuuaaguu cuaauuaugc uuuaaaugau aaauaucaag     1860

aucauaugca ggagcgcaua gauaauuaug aaaauuuaac agugccuuuu guagcugaug     1920

auuauuuagu aaggcaugcu uauaagaacc cuaaugaaau uuauucugaa auaucugaag     1980

uagcaaaauu aaaggaugcu aagagugaag uuaagaaauc acaauauuuu aguaccuuua     2040

cuuugagagg uaguuacaca gguggagcau cuaaggggaa auuagaagau caaaaagcaa     2100

ugaauaaguu uauagaugau ucacuuaaga aauuagauac guauucuugg aguggguaua     2160

aaacuuuaac ugcuuauuuc acuaauuaua aaguugacuc uucaaauaga guuacuuaug     2220

auguaguauu ccacggauau uuaccaaacg aaggugauuc caaaaauuca uuaccuuaug     2280

gcaagaucaa uggaacuuac aagggaacag agaaagaaaa aaucaaauuc ucuagugaag     2340

gcucuuucga uccagauggu aaaauaguuu cuuaugaaug ggauuucgga gaugguaaua     2400

agaguaauga ggaaaaucca gagcauucau augacaaggu aggaacuuau acagugaaau     2460

uaaaaguuac ugaugacaag ggagaaucuu caguaucuac uacuacugca gaaauaaagg     2520

aucuuucaga aaauaaacuu ccaguuauau auaugcaugu accuaaaucc ggagccuuaa     2580

aucaaaaagu uguuuucuau ggaaaaggaa cauaugaccc agauggaucu aucgcaggau     2640

aucaauggga cuuuggugau ggaagugauu uuagcaguga acaaaaccca agccauguau     2700

auacuaaaaa aggugaauau acuguaacau uaagaguaau ggauaguagu ggacaaauga     2760

gugaaaaaac uaugaagauu aagauuacag auccgguaua uccaauaggc acugaaaaag     2820

aaccaaauaa caguaaagaa acugcaagug guccaauagu accagguaua ccuguuagug     2880

gaaccauaga aaauacaagu gaucaagauu auuucuauuu ugauguuaua acaccaggag     2940

aaguaaaaau agauauaaau aaauuagggu acggaggagc uacuugggua guauaugaug     3000

aaaauaauaa ugcaguaucu uaugccacug augaugggca aaauuuaagu ggaaaguuua     3060

aggcagauaa accagguaga uauuacaucc aucuuuacau guuuaauggu aguuauaugc     3120

cauauagaau uaauauagaa gguucaguag gaagauaagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  2598
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  2598
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaauu       60

uuuuaaaaau uauuuuaaau agggggaaga cuaugaaaag gaaauguuua ucuaaaaggc      120

uuauguuagc uauaacaaug gcuacaauau uuacagugaa caguacauua ccaauuuaug      180

cagcuguaga uaaaaauaau gcaacagcag cuguacaaaa ugaaaguaag agguauacag      240

uaucauauuu aaagacuuua aauuauuaug acuuaguaga uuugcuuguu aagacugaaa      300

uugagaauuu accagaccuu uuucaguaua guucagaugc aaaagaguuc uauggaaaua      360

aaacucguau gagcuuuauc auggaugaaa uugguagaag ggcaccucag uauacagaga      420

uagaucauaa agguauuccu acuuuaguag aaguuguaag agcuggauuu uacuuaggau      480

uccauaacaa ggaauugaau gaaauaaaca agaggucuuu uaaagaaagg guaauaccuu      540

cuauauuagc aauucaaaaa aauccuaauu uuaaacuagg uacugaaguu caagauaaaa      600

uaguaucugc aacaggacuu uuagcuggua augaaacagc gccuccagaa guuguaaaua      660

auuuuacacc aauacuucaa gacuguauaa agaauauaga cagauacgcu cuugaugauu      720

uaaagucaaa agcauuauuu aauguuuuag cugcaccuac cuaugauaua acugaguauu      780

uaagagcuac uaaagaaaaa ccagaaaaca cuccuuggua ugguaaaaua gauggguuua      840

uaaaugaacu uaaaaaguua gcucuuuaug gaaaaauaaa ugauaauaac ucuuggauaa      900

uagauaacgg uauauaucau auagcaccuu uagggaaguu acauagcaau aauaaaauag      960

gaauagaaac uuuaacagag guuaugaaag uuuauccuua uuuaaguaug caacauuuac     1020

aaucagcaga ucaaauuaag cgucauuaug auucaaaaga ugcugaagga aacaaaauac     1080

cuuuagauaa guuuaaaaag gaaggaaaag aaaaauacug uccaaaaacu uauacauuug     1140

augauggaaa aguaauaaua aaagcuggug cuagaguaga agaagaaaaa guuaaaagac     1200

uauacugggc aucaaaggaa guuaacucuc aauucuuuag aguauacgga auagacaaac     1260

cauuagaaga agguaaucca gaugauauau uaacaauggu uaucuacaac agucccgaag     1320

aauauaaacu caauaguguu cuauacggau augauacuaa uaaugguggu auguauauag     1380

agccagaagg aacuuucuuc accuaugaaa gagaagcuca agaaagcaca uacacauuag     1440

aagaauuauu uagacaugaa uauacacauu auuugcaagg aagauaugca guuccaggac     1500

aauggggaag aacaaaacuu uaugacaaug auagauuaac uugguaugaa gaagguggag     1560

cagaauuauu ugcagguucu acuagaacuu cuggaauauu accaagaaag aguauaguau     1620

caaauauuca uaauacaaca agaaauaaua gauauaagcu gucagacacu guacauucua     1680

aauauggugc uaguuuugag uucuauaauu augcauguau guuuauggau uauauguaua     1740

auaaagauau ggguauauua aauaaacuaa augaucuugc aaaaaauaau gauguugaug     1800

gauaugauaa uuauauuaga gauuuaaguu cuaauuaugc uuuaaaugau aaauaucaag     1860

aucauaugca ggagcgcaua gauaauuaug aaaauuuaac agugccuuuu guagcugaug     1920

auuauuuagu aaggcaugcu uauaagaacc cuaaugaaau uuauucugaa auaucugaag     1980

uagcaaaauu aaaggaugcu aagagugaag uuaagaaauc acaauauuuu aguaccuuua     2040

cuuugagagg uaguuacaca gguggagcau cuaaggggaa auuagaagau caaaaagcaa     2100

ugaauaaguu uauagaugau ucacuuaaga aauuagauac guauucuugg aguggguaua     2160

aaacuuuaac ugcuuauuuc acuaauuaua aaguugacuc uucaaauaga guuacuuaug     2220

auguaguauu ccacggauau uuaccaaacg aaggugauuc caaaaauuca uuaccuuaug     2280

gcaagaucaa uggaacuuac aagggaacag agaaagaaaa aaucaaauuc ucuagugaag     2340

gcucuuucga uccagauggu aaaauaguuu cuuaugaaug ggauuucgga gaugguaaua     2400

agaguaauga ggaaaaucca gagcauucau augacaaggu aggaacuuau acagugaaau     2460

uaaaaguuac ugaugacaag ggagaaucuu caguaucuac uacuacugca gaaauaaagg     2520

aucuuucaga aaauaaacuu ccaguuauau auaugcaugu accuaaaucc ggagccuuaa     2580

aucaaaaagu uguuuucuau ggaaaaggaa cauaugaccc agauggaucu aucgcaggau     2640

aucaauggga cuuuggugau ggaagugauu uuagcaguga acaaaaccca agccauguau     2700

auacuaaaaa aggugaauau acuguaacau uaagaguaau ggauaguagu ggacaaauga     2760

gugaaaaaac uaugaagauu aagauuacag auccgguaua uccaauaggc acugaaaaag     2820

aaccaaauaa caguaaagaa acugcaagug guccaauagu accagguaua ccuguuagug     2880

gaaccauaga aaauacaagu gaucaagauu auuucuauuu ugauguuaua acaccaggag     2940

aaguaaaaau agauauaaau aaauuagggu acggaggagc uacuugggua guauaugaug     3000

aaaauaauaa ugcaguaucu uaugccacug augaugggca aaauuuaagu ggaaaguuua     3060

aggcagauaa accagguaga uauuacaucc aucuuuacau guuuaauggu aguuauaugc     3120

cauauagaau uaauauagaa gguucaguag gaagauaagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  2599
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  2599
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

ggaaauguuu aucuaaaagg cuuauguuag cuauaacaau ggcuacaaua uuuacaguga      120

acaguacauu accaauuuau gcagcuguag auaaaaauaa ugcaacagca gcuguacaaa      180

augaaaguaa gagguauaca guaucauauu uaaagacuuu aaauuauuau gacuuaguag      240

auuugcuugu uaagacugaa auugagaauu uaccagaccu uuuucaguau aguucagaug      300

caaaagaguu cuauggaaau aaaacucgua ugagcuuuau cauggaugaa auugguagaa      360

gggcaccuca guauacagag auagaucaua aagguauucc uacuuuagua gaaguuguaa      420

gagcuggauu uuacuuagga uuccauaaca aggaauugaa ugaaauaaac aagaggucuu      480

uuaaagaaag gguaauaccu ucuauauuag caauucaaaa aaauccuaau uuuaaacuag      540

guacugaagu ucaagauaaa auaguaucug caacaggacu uuuagcuggu aaugaaacag      600

cgccuccaga aguuguaaau aauuuuacac caauacuuca agacuguaua aagaauauag      660

acagauacgc ucuugaugau uuaaagucaa aagcauuauu uaauguuuua gcugcaccua      720

ccuaugauau aacugaguau uuaagagcua cuaaagaaaa accagaaaac acuccuuggu      780

augguaaaau agauggguuu auaaaugaac uuaaaaaguu agcucuuuau ggaaaaauaa      840

augauaauaa cucuuggaua auagauaacg guauauauca uauagcaccu uuagggaagu      900

uacauagcaa uaauaaaaua ggaauagaaa cuuuaacaga gguuaugaaa guuuauccuu      960

auuuaaguau gcaacauuua caaucagcag aucaaauuaa gcgucauuau gauucaaaag     1020

augcugaagg aaacaaaaua ccuuuagaua aguuuaaaaa ggaaggaaaa gaaaaauacu     1080

guccaaaaac uuauacauuu gaugauggaa aaguaauaau aaaagcuggu gcuagaguag     1140

aagaagaaaa aguuaaaaga cuauacuggg caucaaagga aguuaacucu caauucuuua     1200

gaguauacgg aauagacaaa ccauuagaag aagguaaucc agaugauaua uuaacaaugg     1260

uuaucuacaa cagucccgaa gaauauaaac ucaauagugu ucuauacgga uaugauacua     1320

auaauggugg uauguauaua gagccagaag gaacuuucuu caccuaugaa agagaagcuc     1380

aagaaagcac auacacauua gaagaauuau uuagacauga auauacacau uauuugcaag     1440

gaagauaugc aguuccagga caauggggaa gaacaaaacu uuaugacaau gauagauuaa     1500

cuugguauga agaaggugga gcagaauuau uugcagguuc uacuagaacu ucuggaauau     1560

uaccaagaaa gaguauagua ucaaauauuc auaauacaac aagaaauaau agauauaagc     1620

uuucagacac uguacauucu aaauauggug cuaguuuuga auucuauaau uaugcaugua     1680

uguuuaugga uuauauguau aauaaagaua uggguauauu aaauaaacua aaugaucuug     1740

caaaaaauaa ugauguugau ggauaugaua auuauauuag agauuuaagu ucuaauuaug     1800

cuuuaaauga uaaauaucaa gaucauaugc aggagcgcau agauaauuau gaaaauuuaa     1860

cagugccuuu uguagcugau gauuauuuag uaaggcaugc uuauaagaac ccuaaugaaa     1920

uuuauucuga aauaucugaa guagcaaaau uaaaggaugc uaagagugaa guuaagaaau     1980

cacaauauuu uaguaccuuu acuuugagag guaguuacac agguggagca ucuaagggga     2040

aauuagaaga ucaaaaagca augaauaagu uuauagauga uucacuuaag aaauuagaua     2100

cguauucuug gaguggguau aaaacuuuaa cugcuuauuu cacuaauuau aaaguugacu     2160

cuucaaauag aguuacuuau gauguaguau uccacggaua uuuaccaaac gaaggugauu     2220

ccaaaaauuc auuaccuuau ggcaagauca auggaacuua caagggaaca gagaaagaaa     2280

aaaucaaauu cucuagugaa ggcucuuucg auccagaugg uaaaauaguu ucuuaugaau     2340

gggauuucgg agaugguaau aagaguaaug aggaaaaucc agagcauuca uaugacaagg     2400

uaggaacuua uacagugaaa uuaaaaguua cugaugacaa gggagaaucu ucaguaucua     2460

cuacuacugc agaaauaaag gaucuuucag aaaauaaacu uccaguuaua uauaugcaug     2520

uaccuaaauc cggagccuua aaucaaaaag uuguuuucua uggaaaagga acauaugacc     2580

cagauggauc uaucgcagga uaucaauggg acuuugguga uggaagugau uuuagcagug     2640

aacaaaaccc aagccaugua uauacuaaaa aaggugaaua uacuguaaca uuaagaguaa     2700

uggauaguag uggacaaaug agugaaaaaa cuaugaagau uaagauuaca gauccgguau     2760

auccaauagg cacugaaaaa gaaccaaaua acaguaaaga aacugcaagu gguccaauag     2820

uaccagguau accuguuagu ggaaccauag aaaauacaag ugaucaagau uauuucuauu     2880

uugauguuau aacaccagga gaaguaaaaa uagauauaaa uaaauuaggg uacggaggag     2940

cuacuugggu aguauaugau gaaaauaaua augcaguauc uuaugccacu gaugaugggc     3000

aaaauuuaag uggaaaguuu aaggcagaua aaccagguag auauuacauc caucuuuaca     3060

uguuuaaugg uaguuauaug ccauauagaa uuaauauaga agguucagua ggaagauaag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  2600
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  2600
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

ggaaauguuu aucuaaaagg cuuauguuag cuauaacaau ggcuacaaua uuuacaguga      120

acaguacauu accaauuuau gcagcuguag auaaaaauaa ugcaacagca gcuguacaaa      180

augaaaguaa gagguauaca guaucauauu uaaagacuuu aaauuauuau gacuuaguag      240

auuugcuugu uaagacugaa auugagaauu uaccagaccu uuuucaguau aguucagaug      300

caaaagaguu cuauggaaau aaaacucgua ugagcuuuau cauggaugaa auugguagaa      360

gggcaccuca guauacagag auagaucaua aagguauucc uacuuuagua gaaguuguaa      420

gagcuggauu uuacuuagga uuccauaaca aggaauugaa ugaaauaaac aagaggucuu      480

uuaaagaaag gguaauaccu ucuauauuag caauucaaaa aaauccuaau uuuaaacuag      540

guacugaagu ucaagauaaa auaguaucug caacaggacu uuuagcuggu aaugaaacag      600

cgccuccaga aguuguaaau aauuuuacac caauacuuca agacuguaua aagaauauag      660

acagauacgc ucuugaugau uuaaagucaa aagcauuauu uaauguuuua gcugcaccua      720

ccuaugauau aacugaguau uuaagagcua cuaaagaaaa accagaaaac acuccuuggu      780

augguaaaau agauggguuu auaaaugaac uuaaaaaguu agcucuuuau ggaaaaauaa      840

augauaauaa cucuuggaua auagauaacg guauauauca uauagcaccu uuagggaagu      900

uacauagcaa uaauaaaaua ggaauagaaa cuuuaacaga gguuaugaaa guuuauccuu      960

auuuaaguau gcaacauuua caaucagcag aucaaauuaa gcgucauuau gauucaaaag     1020

augcugaagg aaacaaaaua ccuuuagaua aguuuaaaaa ggaaggaaaa gaaaaauacu     1080

guccaaaaac uuauacauuu gaugauggaa aaguaauaau aaaagcuggu gcuagaguag     1140

aagaagaaaa aguuaaaaga cuauacuggg caucaaagga aguuaacucu caauucuuua     1200

gaguauacgg aauagacaaa ccauuagaag aagguaaucc agaugauaua uuaacaaugg     1260

uuaucuacaa cagucccgaa gaauauaaac ucaauagugu ucuauacgga uaugauacua     1320

auaauggugg uauguauaua gagccagaag gaacuuucuu caccuaugaa agagaagcuc     1380

aagaaagcac auacacauua gaagaauuau uuagacauga auauacacau uauuugcaag     1440

gaagauaugc aguuccagga caauggggaa gaacaaaacu uuaugacaau gauagauuaa     1500

cuugguauga agaaggugga gcagaauuau uugcagguuc uacuagaacu ucuggaauau     1560

uaccaagaaa gaguauagua ucaaauauuc auaauacaac aagaaauaau agauauaagc     1620

ugucagacac uguacauucu aaauauggug cuaguuuuga guucuauaau uaugcaugua     1680

uguuuaugga uuauauguau aauaaagaua uggguauauu aaauaaacua aaugaucuug     1740

caaaaaauaa ugauguugau ggauaugaua auuauauuag agauuuaagu ucuaauuaug     1800

cuuuaaauga uaaauaucaa gaucauaugc aggagcgcau agauaauuau gaaaauuuaa     1860

cagugccuuu uguagcugau gauuauuuag uaaggcaugc uuauaagaac ccuaaugaaa     1920

uuuauucuga aauaucugaa guagcaaaau uaaaggaugc uaagagugaa guuaagaaau     1980

cacaauauuu uaguaccuuu acuuugagag guaguuacac agguggagca ucuaagggga     2040

aauuagaaga ucaaaaagca augaauaagu uuauagauga uucacuuaag aaauuagaua     2100

cguauucuug gaguggguau aaaacuuuaa cugcuuauuu cacuaauuau aaaguugacu     2160

cuucaaauag aguuacuuau gauguaguau uccacggaua uuuaccaaac gaaggugauu     2220

ccaaaaauuc auuaccuuau ggcaagauca auggaacuua caagggaaca gagaaagaaa     2280

aaaucaaauu cucuagugaa ggcucuuucg auccagaugg uaaaauaguu ucuuaugaau     2340

gggauuucgg agaugguaau aagaguaaug aggaaaaucc agagcauuca uaugacaagg     2400

uaggaacuua uacagugaaa uuaaaaguua cugaugacaa gggagaaucu ucaguaucua     2460

cuacuacugc agaaauaaag gaucuuucag aaaauaaacu uccaguuaua uauaugcaug     2520

uaccuaaauc cggagccuua aaucaaaaag uuguuuucua uggaaaagga acauaugacc     2580

cagauggauc uaucgcagga uaucaauggg acuuugguga uggaagugau uuuagcagug     2640

aacaaaaccc aagccaugua uauacuaaaa aaggugaaua uacuguaaca uuaagaguaa     2700

uggauaguag uggacaaaug agugaaaaaa cuaugaagau uaagauuaca gauccgguau     2760

auccaauagg cacugaaaaa gaaccaaaua acaguaaaga aacugcaagu gguccaauag     2820

uaccagguau accuguuagu ggaaccauag aaaauacaag ugaucaagau uauuucuauu     2880

uugauguuau aacaccagga gaaguaaaaa uagauauaaa uaaauuaggg uacggaggag     2940

cuacuugggu aguauaugau gaaaauaaua augcaguauc uuaugccacu gaugaugggc     3000

aaaauuuaag uggaaaguuu aaggcagaua aaccagguag auauuacauc caucuuuaca     3060

uguuuaaugg uaguuauaug ccauauagaa uuaauauaga agguucagua ggaagauaag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  2601
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (wt)

<400>  2601
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

ggguaaccuu uauuucccuu cuuuuucucu uuagcucggc uuauuccgua caaaaugaaa      120

guaagaggua uacaguauca uauuuaaaga cuuuaaauua uuaugacuua guagauuugc      180

uuguuaagac ugaaauugag aauuuaccag accuuuuuca guauaguuca gaugcaaaag      240

aguucuaugg aaauaaaacu cguaugagcu uuaucaugga ugaaauuggu agaagggcac      300

cucaguauac agagauagau cauaaaggua uuccuacuuu aguagaaguu guaagagcug      360

gauuuuacuu aggauuccau aacaaggaau ugaaugaaau aaacaagagg ucuuuuaaag      420

aaaggguaau accuucuaua uuagcaauuc aaaaaaaucc uaauuuuaaa cuagguacug      480

aaguucaaga uaaaauagua ucugcaacag gacuuuuagc ugguaaugaa acagcgccuc      540

cagaaguugu aaauaauuuu acaccaauac uucaagacug uauaaagaau auagacagau      600

acgcucuuga ugauuuaaag ucaaaagcau uauuuaaugu uuuagcugca ccuaccuaug      660

auauaacuga guauuuaaga gcuacuaaag aaaaaccaga aaacacuccu ugguauggua      720

aaauagaugg guuuauaaau gaacuuaaaa aguuagcucu uuauggaaaa auaaaugaua      780

auaacucuug gauaauagau aacgguauau aucauauagc accuuuaggg aaguuacaua      840

gcaauaauaa aauaggaaua gaaacuuuaa cagagguuau gaaaguuuau ccuuauuuaa      900

guaugcaaca uuuacaauca gcagaucaaa uuaagcguca uuaugauuca aaagaugcug      960

aaggaaacaa aauaccuuua gauaaguuua aaaaggaagg aaaagaaaaa uacuguccaa     1020

aaacuuauac auuugaugau ggaaaaguaa uaauaaaagc uggugcuaga guagaagaag     1080

aaaaaguuaa aagacuauac ugggcaucaa aggaaguuaa cucucaauuc uuuagaguau     1140

acggaauaga caaaccauua gaagaaggua auccagauga uauauuaaca augguuaucu     1200

acaacagucc cgaagaauau aaacucaaua guguucuaua cggauaugau acuaauaaug     1260

gugguaugua uauagagcca gaaggaacuu ucuucaccua ugaaagagaa gcucaagaaa     1320

gcacauacac auuagaagaa uuauuuagac augaauauac acauuauuug caaggaagau     1380

augcaguucc aggacaaugg ggaagaacaa aacuuuauga caaugauaga uuaacuuggu     1440

augaagaagg uggagcagaa uuauuugcag guucuacuag aacuucugga auauuaccaa     1500

gaaagaguau aguaucaaau auucauaaua caacaagaaa uaauagauau aagcuuucag     1560

acacuguaca uucuaaauau ggugcuaguu uugaauucua uaauuaugca uguauguuua     1620

uggauuauau guauaauaaa gauaugggua uauuaaauaa acuaaaugau cuugcaaaaa     1680

auaaugaugu ugauggauau gauaauuaua uuagagauuu aaguucuaau uaugcuuuaa     1740

augauaaaua ucaagaucau augcaggagc gcauagauaa uuaugaaaau uuaacagugc     1800

cuuuuguagc ugaugauuau uuaguaaggc augcuuauaa gaacccuaau gaaauuuauu     1860

cugaaauauc ugaaguagca aaauuaaagg augcuaagag ugaaguuaag aaaucacaau     1920

auuuuaguac cuuuacuuug agagguaguu acacaggugg agcaucuaag gggaaauuag     1980

aagaucaaaa agcaaugaau aaguuuauag augauucacu uaagaaauua gauacguauu     2040

cuuggagugg guauaaaacu uuaacugcuu auuucacuaa uuauaaaguu gacucuucaa     2100

auagaguuac uuaugaugua guauuccacg gauauuuacc aaacgaaggu gauuccaaaa     2160

auucauuacc uuauggcaag aucaauggaa cuuacaaggg aacagagaaa gaaaaaauca     2220

aauucucuag ugaaggcucu uucgauccag augguaaaau aguuucuuau gaaugggauu     2280

ucggagaugg uaauaagagu aaugaggaaa auccagagca uucauaugac aagguaggaa     2340

cuuauacagu gaaauuaaaa guuacugaug acaagggaga aucuucagua ucuacuacua     2400

cugcagaaau aaaggaucuu ucagaaaaua aacuuccagu uauauauaug cauguaccua     2460

aauccggagc cuuaaaucaa aaaguuguuu ucuauggaaa aggaacauau gacccagaug     2520

gaucuaucgc aggauaucaa ugggacuuug gugauggaag ugauuuuagc agugaacaaa     2580

acccaagcca uguauauacu aaaaaaggug aauauacugu aacauuaaga guaauggaua     2640

guaguggaca aaugagugaa aaaacuauga agauuaagau uacagauccg guauauccaa     2700

uaggcacuga aaaagaacca aauaacagua aagaaacugc aaguggucca auaguaccag     2760

guauaccugu uaguggaacc auagaaaaua caagugauca agauuauuuc uauuuugaug     2820

uuauaacacc aggagaagua aaaauagaua uaaauaaauu aggguacgga ggagcuacuu     2880

ggguaguaua ugaugaaaau aauaaugcag uaucuuaugc cacugaugau gggcaaaauu     2940

uaaguggaaa guuuaaggca gauaaaccag guagauauua cauccaucuu uacauguuua     3000

augguaguua uaugccauau agaauuaaua uagaagguuc aguaggaaga uaaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  2602
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (wt)

<400>  2602
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

ggguaaccuu uauuucccuu cuuuuucucu uuagcucggc uuauuccgua caaaaugaaa      120

guaagaggua uacaguauca uauuuaaaga cuuuaaauua uuaugacuua guagauuugc      180

uuguuaagac ugaaauugag aauuuaccag accuuuuuca guauaguuca gaugcaaaag      240

aguucuaugg aaauaaaacu cguaugagcu uuaucaugga ugaaauuggu agaagggcac      300

cucaguauac agagauagau cauaaaggua uuccuacuuu aguagaaguu guaagagcug      360

gauuuuacuu aggauuccau aacaaggaau ugaaugaaau aaacaagagg ucuuuuaaag      420

aaaggguaau accuucuaua uuagcaauuc aaaaaaaucc uaauuuuaaa cuagguacug      480

aaguucaaga uaaaauagua ucugcaacag gacuuuuagc ugguaaugaa acagcgccuc      540

cagaaguugu aaauaauuuu acaccaauac uucaagacug uauaaagaau auagacagau      600

acgcucuuga ugauuuaaag ucaaaagcau uauuuaaugu uuuagcugca ccuaccuaug      660

auauaacuga guauuuaaga gcuacuaaag aaaaaccaga aaacacuccu ugguauggua      720

aaauagaugg guuuauaaau gaacuuaaaa aguuagcucu uuauggaaaa auaaaugaua      780

auaacucuug gauaauagau aacgguauau aucauauagc accuuuaggg aaguuacaua      840

gcaauaauaa aauaggaaua gaaacuuuaa cagagguuau gaaaguuuau ccuuauuuaa      900

guaugcaaca uuuacaauca gcagaucaaa uuaagcguca uuaugauuca aaagaugcug      960

aaggaaacaa aauaccuuua gauaaguuua aaaaggaagg aaaagaaaaa uacuguccaa     1020

aaacuuauac auuugaugau ggaaaaguaa uaauaaaagc uggugcuaga guagaagaag     1080

aaaaaguuaa aagacuauac ugggcaucaa aggaaguuaa cucucaauuc uuuagaguau     1140

acggaauaga caaaccauua gaagaaggua auccagauga uauauuaaca augguuaucu     1200

acaacagucc cgaagaauau aaacucaaua guguucuaua cggauaugau acuaauaaug     1260

gugguaugua uauagagcca gaaggaacuu ucuucaccua ugaaagagaa gcucaagaaa     1320

gcacauacac auuagaagaa uuauuuagac augaauauac acauuauuug caaggaagau     1380

augcaguucc aggacaaugg ggaagaacaa aacuuuauga caaugauaga uuaacuuggu     1440

augaagaagg uggagcagaa uuauuugcag guucuacuag aacuucugga auauuaccaa     1500

gaaagaguau aguaucaaau auucauaaua caacaagaaa uaauagauau aagcugucag     1560

acacuguaca uucuaaauau ggugcuaguu uugaguucua uaauuaugca uguauguuua     1620

uggauuauau guauaauaaa gauaugggua uauuaaauaa acuaaaugau cuugcaaaaa     1680

auaaugaugu ugauggauau gauaauuaua uuagagauuu aaguucuaau uaugcuuuaa     1740

augauaaaua ucaagaucau augcaggagc gcauagauaa uuaugaaaau uuaacagugc     1800

cuuuuguagc ugaugauuau uuaguaaggc augcuuauaa gaacccuaau gaaauuuauu     1860

cugaaauauc ugaaguagca aaauuaaagg augcuaagag ugaaguuaag aaaucacaau     1920

auuuuaguac cuuuacuuug agagguaguu acacaggugg agcaucuaag gggaaauuag     1980

aagaucaaaa agcaaugaau aaguuuauag augauucacu uaagaaauua gauacguauu     2040

cuuggagugg guauaaaacu uuaacugcuu auuucacuaa uuauaaaguu gacucuucaa     2100

auagaguuac uuaugaugua guauuccacg gauauuuacc aaacgaaggu gauuccaaaa     2160

auucauuacc uuauggcaag aucaauggaa cuuacaaggg aacagagaaa gaaaaaauca     2220

aauucucuag ugaaggcucu uucgauccag augguaaaau aguuucuuau gaaugggauu     2280

ucggagaugg uaauaagagu aaugaggaaa auccagagca uucauaugac aagguaggaa     2340

cuuauacagu gaaauuaaaa guuacugaug acaagggaga aucuucagua ucuacuacua     2400

cugcagaaau aaaggaucuu ucagaaaaua aacuuccagu uauauauaug cauguaccua     2460

aauccggagc cuuaaaucaa aaaguuguuu ucuauggaaa aggaacauau gacccagaug     2520

gaucuaucgc aggauaucaa ugggacuuug gugauggaag ugauuuuagc agugaacaaa     2580

acccaagcca uguauauacu aaaaaaggug aauauacugu aacauuaaga guaauggaua     2640

guaguggaca aaugagugaa aaaacuauga agauuaagau uacagauccg guauauccaa     2700

uaggcacuga aaaagaacca aauaacagua aagaaacugc aaguggucca auaguaccag     2760

guauaccugu uaguggaacc auagaaaaua caagugauca agauuauuuc uauuuugaug     2820

uuauaacacc aggagaagua aaaauagaua uaaauaaauu aggguacgga ggagcuacuu     2880

ggguaguaua ugaugaaaau aauaaugcag uaucuuaugc cacugaugau gggcaaaauu     2940

uaaguggaaa guuuaaggca gauaaaccag guagauauua cauccaucuu uacauguuua     3000

augguaguua uaugccauau agaauuaaua uagaagguuc aguaggaaga uaaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  2603
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (wt)

<400>  2603
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

ggguaaccuu uauuucccuu cuuuuucucu uuagcucggc uuauuccaug aaaaggaaau      120

guuuaucuaa aaggcuuaug uuagcuauaa caauggcuac aauauuuaca gugaacagua      180

cauuaccaau uuaugcagcu guagauaaaa auaaugcaac agcagcuaga aggcggcgca      240

agagaguaca aaaugaaagu aagagguaua caguaucaua uuuaaagacu uuaaauuauu      300

augacuuagu agauuugcuu guuaagacug aaauugagaa uuuaccagac cuuuuucagu      360

auaguucaga ugcaaaagag uucuauggaa auaaaacucg uaugagcuuu aucauggaug      420

aaauugguag aagggcaccu caguauacag agauagauca uaaagguauu ccuacuuuag      480

uagaaguugu aagagcugga uuuuacuuag gauuccauaa caaggaauug aaugaaauaa      540

acaagagguc uuuuaaagaa aggguaauac cuucuauauu agcaauucaa aaaaauccua      600

auuuuaaacu agguacugaa guucaagaua aaauaguauc ugcaacagga cuuuuagcug      660

guaaugaaac agcgccucca gaaguuguaa auaauuuuac accaauacuu caagacugua      720

uaaagaauau agacagauac gcucuugaug auuuaaaguc aaaagcauua uuuaauguuu      780

uagcugcacc uaccuaugau auaacugagu auuuaagagc uacuaaagaa aaaccagaaa      840

acacuccuug guaugguaaa auagaugggu uuauaaauga acuuaaaaag uuagcucuuu      900

auggaaaaau aaaugauaau aacucuugga uaauagauaa cgguauauau cauauagcac      960

cuuuagggaa guuacauagc aauaauaaaa uaggaauaga aacuuuaaca gagguuauga     1020

aaguuuaucc uuauuuaagu augcaacauu uacaaucagc agaucaaauu aagcgucauu     1080

augauucaaa agaugcugaa ggaaacaaaa uaccuuuaga uaaguuuaaa aaggaaggaa     1140

aagaaaaaua cuguccaaaa acuuauacau uugaugaugg aaaaguaaua auaaaagcug     1200

gugcuagagu agaagaagaa aaaguuaaaa gacuauacug ggcaucaaag gaaguuaacu     1260

cucaauucuu uagaguauac ggaauagaca aaccauuaga agaagguaau ccagaugaua     1320

uauuaacaau gguuaucuac aacagucccg aagaauauaa acucaauagu guucuauacg     1380

gauaugauac uaauaauggu gguauguaua uagagccaga aggaacuuuc uucaccuaug     1440

aaagagaagc ucaagaaagc acauacacau uagaagaauu auuuagacau gaauauacac     1500

auuauuugca aggaagauau gcaguuccag gacaaugggg aagaacaaaa cuuuaugaca     1560

augauagauu aacuugguau gaagaaggug gagcagaauu auuugcaggu ucuacuagaa     1620

cuucuggaau auuaccaaga aagaguauag uaucaaauau ucauaauaca acaagaaaua     1680

auagauauaa gcuuucagac acuguacauu cuaaauaugg ugcuaguuuu gaauucuaua     1740

auuaugcaug uauguuuaug gauuauaugu auaauaaaga uauggguaua uuaaauaaac     1800

uaaaugaucu ugcaaaaaau aaugauguug auggauauga uaauuauauu agagauuuaa     1860

guucuaauua ugcuuuaaau gauaaauauc aagaucauau gcaggagcgc auagauaauu     1920

augaaaauuu aacagugccu uuuguagcug augauuauuu aguaaggcau gcuuauaaga     1980

acccuaauga aauuuauucu gaaauaucug aaguagcaaa auuaaaggau gcuaagagug     2040

aaguuaagaa aucacaauau uuuaguaccu uuacuuugag agguaguuac acagguggag     2100

caucuaaggg gaaauuagaa gaucaaaaag caaugaauaa guuuauagau gauucacuua     2160

agaaauuaga uacguauucu uggagugggu auaaaacuuu aacugcuuau uucacuaauu     2220

auaaaguuga cucuucaaau agaguuacuu augauguagu auuccacgga uauuuaccaa     2280

acgaagguga uuccaaaaau ucauuaccuu auggcaagau caauggaacu uacaagggaa     2340

cagagaaaga aaaaaucaaa uucucuagug aaggcucuuu cgauccagau gguaaaauag     2400

uuucuuauga augggauuuc ggagauggua auaagaguaa ugaggaaaau ccagagcauu     2460

cauaugacaa gguaggaacu uauacaguga aauuaaaagu uacugaugac aagggagaau     2520

cuucaguauc uacuacuacu gcagaaauaa aggaucuuuc agaaaauaaa cuuccaguua     2580

uauauaugca uguaccuaaa uccggagccu uaaaucaaaa aguuguuuuc uauggaaaag     2640

gaacauauga cccagaugga ucuaucgcag gauaucaaug ggacuuuggu gauggaagug     2700

auuuuagcag ugaacaaaac ccaagccaug uauauacuaa aaaaggugaa uauacuguaa     2760

cauuaagagu aauggauagu aguggacaaa ugagugaaaa aacuaugaag auuaagauua     2820

cagauccggu auauccaaua ggcacugaaa aagaaccaaa uaacaguaaa gaaacugcaa     2880

gugguccaau aguaccaggu auaccuguua guggaaccau agaaaauaca agugaucaag     2940

auuauuucua uuuugauguu auaacaccag gagaaguaaa aauagauaua aauaaauuag     3000

gguacggagg agcuacuugg guaguauaug augaaaauaa uaaugcagua ucuuaugcca     3060

cugaugaugg gcaaaauuua aguggaaagu uuaaggcaga uaaaccaggu agauauuaca     3120

uccaucuuua cauguuuaau gguaguuaua ugccauauag aauuaauaua gaagguucag     3180

uaggaagaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  2604
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (wt)

<400>  2604
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

ggguaaccuu uauuucccuu cuuuuucucu uuagcucggc uuauuccaug aaaaggaaau      120

guuuaucuaa aaggcuuaug uuagcuauaa caauggcuac aauauuuaca gugaacagua      180

cauuaccaau uuaugcagcu guagauaaaa auaaugcaac agcagcuaga aggcggcgca      240

agagaguaca aaaugaaagu aagagguaua caguaucaua uuuaaagacu uuaaauuauu      300

augacuuagu agauuugcuu guuaagacug aaauugagaa uuuaccagac cuuuuucagu      360

auaguucaga ugcaaaagag uucuauggaa auaaaacucg uaugagcuuu aucauggaug      420

aaauugguag aagggcaccu caguauacag agauagauca uaaagguauu ccuacuuuag      480

uagaaguugu aagagcugga uuuuacuuag gauuccauaa caaggaauug aaugaaauaa      540

acaagagguc uuuuaaagaa aggguaauac cuucuauauu agcaauucaa aaaaauccua      600

auuuuaaacu agguacugaa guucaagaua aaauaguauc ugcaacagga cuuuuagcug      660

guaaugaaac agcgccucca gaaguuguaa auaauuuuac accaauacuu caagacugua      720

uaaagaauau agacagauac gcucuugaug auuuaaaguc aaaagcauua uuuaauguuu      780

uagcugcacc uaccuaugau auaacugagu auuuaagagc uacuaaagaa aaaccagaaa      840

acacuccuug guaugguaaa auagaugggu uuauaaauga acuuaaaaag uuagcucuuu      900

auggaaaaau aaaugauaau aacucuugga uaauagauaa cgguauauau cauauagcac      960

cuuuagggaa guuacauagc aauaauaaaa uaggaauaga aacuuuaaca gagguuauga     1020

aaguuuaucc uuauuuaagu augcaacauu uacaaucagc agaucaaauu aagcgucauu     1080

augauucaaa agaugcugaa ggaaacaaaa uaccuuuaga uaaguuuaaa aaggaaggaa     1140

aagaaaaaua cuguccaaaa acuuauacau uugaugaugg aaaaguaaua auaaaagcug     1200

gugcuagagu agaagaagaa aaaguuaaaa gacuauacug ggcaucaaag gaaguuaacu     1260

cucaauucuu uagaguauac ggaauagaca aaccauuaga agaagguaau ccagaugaua     1320

uauuaacaau gguuaucuac aacagucccg aagaauauaa acucaauagu guucuauacg     1380

gauaugauac uaauaauggu gguauguaua uagagccaga aggaacuuuc uucaccuaug     1440

aaagagaagc ucaagaaagc acauacacau uagaagaauu auuuagacau gaauauacac     1500

auuauuugca aggaagauau gcaguuccag gacaaugggg aagaacaaaa cuuuaugaca     1560

augauagauu aacuugguau gaagaaggug gagcagaauu auuugcaggu ucuacuagaa     1620

cuucuggaau auuaccaaga aagaguauag uaucaaauau ucauaauaca acaagaaaua     1680

auagauauaa gcugucagac acuguacauu cuaaauaugg ugcuaguuuu gaguucuaua     1740

auuaugcaug uauguuuaug gauuauaugu auaauaaaga uauggguaua uuaaauaaac     1800

uaaaugaucu ugcaaaaaau aaugauguug auggauauga uaauuauauu agagauuuaa     1860

guucuaauua ugcuuuaaau gauaaauauc aagaucauau gcaggagcgc auagauaauu     1920

augaaaauuu aacagugccu uuuguagcug augauuauuu aguaaggcau gcuuauaaga     1980

acccuaauga aauuuauucu gaaauaucug aaguagcaaa auuaaaggau gcuaagagug     2040

aaguuaagaa aucacaauau uuuaguaccu uuacuuugag agguaguuac acagguggag     2100

caucuaaggg gaaauuagaa gaucaaaaag caaugaauaa guuuauagau gauucacuua     2160

agaaauuaga uacguauucu uggagugggu auaaaacuuu aacugcuuau uucacuaauu     2220

auaaaguuga cucuucaaau agaguuacuu augauguagu auuccacgga uauuuaccaa     2280

acgaagguga uuccaaaaau ucauuaccuu auggcaagau caauggaacu uacaagggaa     2340

cagagaaaga aaaaaucaaa uucucuagug aaggcucuuu cgauccagau gguaaaauag     2400

uuucuuauga augggauuuc ggagauggua auaagaguaa ugaggaaaau ccagagcauu     2460

cauaugacaa gguaggaacu uauacaguga aauuaaaagu uacugaugac aagggagaau     2520

cuucaguauc uacuacuacu gcagaaauaa aggaucuuuc agaaaauaaa cuuccaguua     2580

uauauaugca uguaccuaaa uccggagccu uaaaucaaaa aguuguuuuc uauggaaaag     2640

gaacauauga cccagaugga ucuaucgcag gauaucaaug ggacuuuggu gauggaagug     2700

auuuuagcag ugaacaaaac ccaagccaug uauauacuaa aaaaggugaa uauacuguaa     2760

cauuaagagu aauggauagu aguggacaaa ugagugaaaa aacuaugaag auuaagauua     2820

cagauccggu auauccaaua ggcacugaaa aagaaccaaa uaacaguaaa gaaacugcaa     2880

gugguccaau aguaccaggu auaccuguua guggaaccau agaaaauaca agugaucaag     2940

auuauuucua uuuugauguu auaacaccag gagaaguaaa aauagauaua aauaaauuag     3000

gguacggagg agcuacuugg guaguauaug augaaaauaa uaaugcagua ucuuaugcca     3060

cugaugaugg gcaaaauuua aguggaaagu uuaaggcaga uaaaccaggu agauauuaca     3120

uccaucuuua cauguuuaau gguaguuaua ugccauauag aauuaauaua gaagguucag     3180

uaggaagaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  2605
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (wt)

<400>  2605
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu auuugccugc cuccugggag cagcuuuugc caugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggugcu uaccccuuug aagugguacc      180

agagcauaag gccaccguac ccuuccuaug guuacgagcc caugggugga uggcugcacc      240

accaaaucau ccccgugcug ucccaacagc accccccgac ucacacccug cagccucauc      300

accacauccc aguggugcca gcucagcagc ccgugauccc ccagcaacca augaugcccg      360

uuccuggcca acacuccaug acuccaaucc aacaccacca gccaaaccuc ccuccgcccg      420

cccagcagcc cuaccagccc cagccuguuc agccacagcc ucaccagccc augcagcccc      480

agccaccugu gcaccccaug cagccccugc cgccacagcc accucugccu ccgauguucc      540

ccaugcagcc ccugccuccc augcuuccug aucugacucu ggaagcuugg ccaucaacag      600

acaagaccaa gcgggaggaa guggauuaag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  2606
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (wt)

<400>  2606
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu auuugccugc cuccugggag cagcuuuugc caugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggugcu uaccccuuug aagugguacc      180

agagcauaag gccaccguac ccuuccuaug guuacgagcc caugggugga uggcugcacc      240

accaaaucau ccccgugcug ucccaacagc accccccgac ucacacccug cagccucauc      300

accacauccc aguggugcca gcucagcagc ccgugauccc ccagcaacca augaugcccg      360

uuccuggcca acacuccaug acuccaaucc aacaccacca gccaaaccuc ccuccgcccg      420

cccagcagcc cuaccagccc cagccuguuc agccacagcc ucaccagccc augcagcccc      480

agccaccugu gcaccccaug cagccccugc cgccacagcc accucugccu ccgauguucc      540

ccaugcagcc ccugccuccc augcuuccug aucugacucu ggaagcaugg ccaucaacag      600

acaagaccaa gcgggaggaa guggauuaag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  2607
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (wt)

<400>  2607
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug cuuaccccuu      120

ugaaguggua ccagagcaua aggccaccgu acccuuccua ugguuacgag cccaugggug      180

gaugguaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  2608
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (wt)

<400>  2608
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug cuuaccccuu      120

ugaaguggua ccagagcaua aggccaccuc ccaugcuucc ugaucugacu cuggaagcuu      180

ggccaucaac agacaagacc aagcgggagg aaguggauua aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  2609
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (wt)

<400>  2609
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug cuuaccccuu      120

ugaaguggua ccagagcaua aggccaccuc ccaugcuucc ugaucugacu cuggaagcau      180

ggccaucaac agacaagacc aagcgggagg aaguggauua aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  2610
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (wt)

<400>  2610
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcgcc ccgaacccuc guccugcuac ucucgggggc ucuggcccug acccagaccu      120

gggcgaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc uuugaagugg uaccagagca uaaggccacc guacccuucc uaugguuacg      240

agcccauggg uggaugguaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  2611
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (wt)

<400>  2611
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcgcc ccgaacccuc guccugcuac ucucgggggc ucuggcccug acccagaccu      120

gggcgaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc uuugaagugg uaccagagca uaaggccacc ucccaugcuu ccugaucuga      240

cucuggaagc auggccauca acagacaaga ccaagcggga ggaaguggau uaaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  2612
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (wt)

<400>  2612
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu guuugccugc cuugugggag cagcuuuugc caugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggugcu caccccuuug aagugguacc      180

agagcaugau aagaccacca uacucuuccu augguuacga gcccaugggu ggauggcugc      240

accaccaaau cauccccgug gugucccaac agcacccccu gacucacacc cugcagucuc      300

aucaccacau cccaguggug ccagcucagc agcccagggu ccgccagcaa gcacugaugc      360

cuguuccugg ccagcaaucc augacuccaa cccaacacca ucagccaaac cucccucugc      420

cugcccagca gcccuuccag ccccagccug uucagccaca gccucaccag cccaugcagc      480

cccagccacc ugugcaaccc augcagcccc ugcugccaca gccaccucug ccuccaaugu      540

ucccccugcg gccccugccc cccauacuuc cugaucugca ucuggaagcu uggccagcaa      600

cagacaagac caagcaggag gaaguggauu aaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  2613
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (wt)

<400>  2613
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu guuugccugc cuugugggag cagcuuuugc caugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggugcu caccccuuug aagugguacc      180

agagcaugau aagaccacca uacucuuccu augguuacga gcccaugggu ggauggcugc      240

accaccaaau cauccccgug gugucccaac agcacccccu gacucacacc cugcagucuc      300

aucaccacau cccaguggug ccagcucagc agcccagggu ccgccagcaa gcacugaugc      360

cuguuccugg ccagcaaucc augacuccaa cccaacacca ucagccaaac cucccucugc      420

cugcccagca gcccuuccag ccccagccug uucagccaca gccucaccag cccaugcagc      480

cccagccacc ugugcaaccc augcagcccc ugcugccaca gccaccucug ccuccaaugu      540

ucccccugcg gccccugccc cccauacuuc cugaucugca ucuggaagca uggccagcaa      600

cagacaagac caagcaggag gaaguggauu aaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  2614
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (wt)

<400>  2614
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug cucaccccuu      120

ugaaguggua ccagagcaug auaagaccac cauacucuuc cuaugguuac gagcccaugg      180

guggauggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  2615
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (wt)

<400>  2615
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug cucaccccuu      120

ugaaguggua ccagagcaug auaagaccac cccccauacu uccugaucug caucuggaag      180

cuuggccagc aacagacaag accaagcagg aggaagugga uuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  2616
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (wt)

<400>  2616
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug cucaccccuu      120

ugaaguggua ccagagcaug auaagaccac cccccauacu uccugaucug caucuggaag      180

cauggccagc aacagacaag accaagcagg aggaagugga uuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  2617
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (wt)

<400>  2617
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcgcc ccgaacccuc guccugcuac ucucgggggc ucuggcccug acccagaccu      120

gggcgaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcucacccc uuugaagugg uaccagagca ugauaagacc accauacucu uccuaugguu      240

acgagcccau ggguggaugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  2618
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (wt)

<400>  2618
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcgcc ccgaacccuc guccugcuac ucucgggggc ucuggcccug acccagaccu      120

gggcgaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcucacccc uuugaagugg uaccagagca ugauaagacc accccccaua cuuccugauc      240

ugcaucugga agcauggcca gcaacagaca agaccaagca ggaggaagug gauuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  2619
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (wt)

<400>  2619
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu guuugcuugc cuccugggag cagccuucuc uaugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggugcu uaccccucug aagugguacc      180

agaacaugau aagacauccg uacacuuccu auggguacga acccaugggu ggauggcugc      240

accaccaaau cauacccgug gugucgcagc agacucccca gagucaugcc cuucagccuc      300

aucaccacau ccccauggug ccagcucaac agcccgggau cccccagcag ccaaugaugc      360

cacuuccugg ccaacacucc augacuccaa cccaacacca ccagccaaac cucccucugc      420

ccgcccagca gcccuuccag ccccagcccg uccagcccca gccucaccag ccccugcagc      480

cccagucacc caugcacccc auccagcccu ugcugccaca gccaccucug ccuccgaugu      540

ucuccaugca gucucugcuu ccugaccugc cucuggaagc uuggccagca acagacaaga      600

ccaagcggga ggaaguggau uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  2620
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (wt)

<400>  2620
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu guuugcuugc cuccugggag cagccuucuc uaugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggugcu uaccccucug aagugguacc      180

agaacaugau aagacauccg uacacuuccu auggguacga acccaugggu ggauggcugc      240

accaccaaau cauacccgug gugucgcagc agacucccca gagucaugcc cuucagccuc      300

aucaccacau ccccauggug ccagcucaac agcccgggau cccccagcag ccaaugaugc      360

cacuuccugg ccaacacucc augacuccaa cccaacacca ccagccaaac cucccucugc      420

ccgcccagca gcccuuccag ccccagcccg uccagcccca gccucaccag ccccugcagc      480

cccagucacc caugcacccc auccagcccu ugcugccaca gccaccucug ccuccgaugu      540

ucuccaugca gucucugcuu ccugaccugc cucuggaagc auggccagca acagacaaga      600

ccaagcggga ggaaguggau uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  2621
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (wt)

<400>  2621
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug cuuaccccuc      120

ugaaguggua ccagaacaug auaagacauc cguacacuuc cuauggguac gaacccaugg      180

guggauggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  2622
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (wt)

<400>  2622
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug cuuaccccuc      120

ugaaguggua ccagaacaug auaagacauc cgucucugcu uccugaccug ccucuggaag      180

cuuggccagc aacagacaag accaagcggg aggaagugga uuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  2623
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (wt)

<400>  2623
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug cuuaccccuc      120

ugaaguggua ccagaacaug auaagacauc cgucucugcu uccugaccug ccucuggaag      180

cauggccagc aacagacaag accaagcggg aggaagugga uuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  2624
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (wt)

<400>  2624
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcgcc ccgaacccuc guccugcuac ucucgggggc ucuggcccug acccagaccu      120

gggcgaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccguacacu uccuaugggu      240

acgaacccau ggguggaugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  2625
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (wt)

<400>  2625
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcgcc ccgaacccuc guccugcuac ucucgggggc ucuggcccug acccagaccu      120

gggcgaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccgucucug cuuccugacc      240

ugccucugga agcauggcca gcaacagaca agaccaagcg ggaggaagug gauuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  2626
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (wt)

<400>  2626
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu guuugcuugc cuccugggag cagccuucuc uaugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu auauaagaca uccguacacu uccuaugggu      180

acgaacccau ggguggaugg cugcaccacc aaaucauacc cguggugucg cagcagacuc      240

cccagaguca ugcccuucag ccucaucacc acauccccau ggugccagcu caacagcccg      300

ggauccccca gcagccaaug augccacuuc cuggccaaca cuccaugacu ccaacccaac      360

accaccagcc aaaccucccu cugcccgccc agcagcccuu ccagccccag cccguccagc      420

cccagccuca ccagccccug cagccccagu cacccaugca ccccauccag cccuugcugc      480

cacagccacc ucugccuccg auguucucca ugcagucucu gcuuccugac cugccucugg      540

aagcuuggcc agcaacagac aagaccaagc gggaggaagu ggauuaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  2627
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (wt)

<400>  2627
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu cuuugccugc cuuuugggag caucccuugc uaugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggugcu uaccccucug aagugguacc      180

agaacaugau aagacauccg uacacuuccu auggguacga acccaugggu ggauggcugc      240

accaccaaau cauacccgug gugucgcagc agacucccca gagucaugcc cuucagccuc      300

aucaccacau ccccauggug ccagcucaac agcccgggau cccccagcag ccaaugaugc      360

cacuuccugg ccaacacucc augacuccaa cccaacacca ccagccaaac cucccucugc      420

ccgcccagca gcccuuccag ccccagcccg uccagcccca gccucaccag ccccugcagc      480

cccagucacc caugcacccc auccagcccu ugcugccaca gccaccucug ccuccgaugu      540

ucuccaugca gucucugcuu ccugaccugc cucuggaagc uuggccagca acagacaaga      600

ccaagcggga ggaaguggau uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  2628
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (wt)

<400>  2628
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu guuugcuugc cuccugggag cagccuucuc uaugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggugcu uaccccucug aagugguacc      180

agaacaugau aagacauccg ucucugcuuc cugaccugcc ucuggaagcu uggccagcaa      240

cagacaagac caagcgggag gaaguggauu aaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  2629
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (wt)

<400>  2629
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu guuugcuugc cuccugggag cagccuucuc uaugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggacuu auacuuggag gcuauccgua      180

uugacaggac ugcauucgug cuuaccccuc ugaaguggua ccagaacaug auaagacauc      240

cguacacuuc cuaugguuac gaacccaugg guggauggcu gcaccaccaa aucauucccg      300

uggugucgca gcagacuccc cagagucaug cccuucagcc ucaucaccac auccccaugg      360

ugccagcuca acagcccggg aucccccagc agccaaugau gccacuuccu ggccaacacu      420

ccaugacucc aacccaacac caccagccaa accucccucu gcccgcccag cagcccuucc      480

agccccagcc cguccagccc cagccucacc agccccugca gccccaguca cccaugcacc      540

ccauccagcc cuugcugcca cagccaccuc ugccuccgau guucuccaug cagucucugc      600

uuccugaccu gccucuggaa gcuuggccag caacagacaa gaccaagcgg gaggaagugg      660

auuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  2630
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (wt)

<400>  2630
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu guuugcuugc cuccugggag cagccuucuc uaugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggugcu uaccccucug aagugguacc      180

agaacaugau aagacauccg acuccccaga gucaugcccu ucagccucau caccacaucc      240

ccauggugcc agcucaacag cccgggaucc cccagcagcc aaugaugcca cuuccuggcc      300

aacacuccau gacuccaacc caacaccacc agccaaaccu cccucugccc gcccagcagc      360

ccuuccagcc ccagcccguc cagccccagc cucaccagcc ccugcagccc cagucaccca      420

ugcaccccau ccagcccuug cugccacagc caccucugcc uccgauguuc uccaugcagu      480

cucugcuucc ugaccugccu cuggaagcuu ggccagcaac agacaagacc aagcgggagg      540

aaguggauua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  2631
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (wt)

<400>  2631
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug cuuaccccuc      120

ugaaguggua ccagaacaug auaagacauc cguacacuuc cuauggguac gaacccaugg      180

guggauggcu gcaccaccaa aucauacccg uggugucgca gcagacuccc cagagucaug      240

cccuucagcc ucaucaccac auccccaugg ugccagcuca acagcccggg aucccccagc      300

agccaaugau gccacuuccu ggccaacacu ccaugacucc aacccaacac caccagccaa      360

accucccucu gcccgcccag cagcccuucc agccccagcc cguccagccc cagccucacc      420

agccccugca gccccaguca cccaugcacc ccauccagcc cuugcugcca cagccaccuc      480

ugccuccgau guucuccaug cagucucugc uuccugaccu gccucuggaa gcuuggccag      540

caacagacaa gaccaagcgg gaggaagugg auuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  2632
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (wt)

<400>  2632
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gcguggcccg ccugccgcug cugcucgggc ugcugcugcu cccgcguccc ggccggccgc      120

uggacuuggc cgacuacacc uaugaccugg cggaggagga cgacucggag ccccucaacu      180

acaaagaccc cugcaaggcg gcugccuuuc uuggggacau ugcccuggac gaagaggacc      240

ugagggccuu ccagguacag caggcugugg aucucagacg gcacacagcu cguaaguccu      300

ccaucaaagc ugcaguucca ggaaacacuu cuacccccag cugccagagc accaacgggc      360

agccucagag gggagccugu gggagaugga gagguagauc ccguagccgg cgggcggcga      420

cgucccgacc agagcgugug uggcccgaug gggucauccc cuuugucauu gggggaaacu      480

ucacugguag ccagagggca gucuuccggc aggccaugag gcacugggag aagcacaccu      540

gugucaccuu ccuggagcgc acugacgagg acagcuauau uguguucacc uaucgaccuu      600

gcgggugcug cuccuacgug ggucgccgcg gcgggggccc ccaggccauc uccaucggca      660

agaacuguga caaguucggc auuguggucc acgagcuggg ccacgucguc ggcuucuggc      720

acgaacacac ucggccagac cgggaccgcc acguuuccau cguucgugag aacauccagc      780

cagggcagga guauaacuuc cugaagaugg agccucagga gguggagucc cugggggaga      840

ccuaugacuu cgacagcauc augcauuacg cucggaacac auucuccagg ggcaucuucc      900

uggauaccau uguccccaag uaugagguga acggggugaa accucccauu ggccaaagga      960

cacggcucag caagggggac auugcccaag cccgcaagcu uuacaagugc ccagccugug     1020

gagagacccu gcaagacagc acaggcaacu ucuccucccc ugaauacccc aauggcuacu     1080

cugcucacau gcacugcgug uggcgcaucu cugucacacc cggggagaag aucauccuga     1140

acuucacguc ccuggaccug uaccgcagcc gccugugcug guacgacuau guggaggucc     1200

gagauggcuu cuggaggaag gcgccccucc gaggccgcuu cugcgggucc aaacucccug     1260

agccuaucgu cuccacugac agccgccucu ggguugaauu ccgcagcagc agcaauuggg     1320

uuggaaaggg cuucuuugca gucuacgaag ccaucugcgg gggugaugug aaaaaggacu     1380

auggccacau ucaaucgccc aacuacccag acgauuaccg gcccagcaaa gucugcaucu     1440

ggcggaucca ggugucugag ggcuuccacg ugggccucac auuccagucc uuugagauug     1500

agcgccacga cagcugugcc uacgacuauc uggaggugcg cgacgggcac agugagagca     1560

gcacccucau cgggcgcuac uguggcuaug agaagccuga ugacaucaag agcacgucca     1620

gccgccucug gcucaaguuc gucucugacg gguccauuaa caaagcgggc uuugccguca     1680

acuuuuucaa agagguggac gagugcucuc ggcccaaccg cgggggcugu gagcagcggu     1740

gccucaacac ccugggcagc uacaagugca gcugugaccc cggguacgag cuggccccag     1800

acaagcgccg cugugaggcu gcuuguggcg gauuccucac caagcucaac ggcuccauca     1860

ccagcccggg cuggcccaag gaguaccccc ccaacaagaa cugcaucugg cagcuggugg     1920

cccccaccca guaccgcauc ucccugcagu uugacuucuu ugagacagag ggcaaugaug     1980

ugugcaagua cgacuucgug gaggugcgca guggacucac agcugacucc aagcugcaug     2040

gcaaguucug ugguucugag aagcccgagg ucaucaccuc ccaguacaac aacaugcgcg     2100

uggaguucaa guccgacaac accgugucca aaaagggcuu caaggcccac uucuucucag     2160

acaaggacga gugcuccaag gauaacggcg gcugccagca ggacugcguc aacacguucg     2220

gcaguuauga gugccaaugc cgcaguggcu ucguccucca ugacaacaag cacgacugca     2280

aagaagccgg cugugaccac aaggugacau ccaccagugg uaccaucacc agccccaacu     2340

ggccugacaa guaucccagc aagaaggagu gcacgugggc caucuccagc acccccgggc     2400

accgggucaa gcugaccuuc auggagaugg acaucgaguc ccagccugag ugugccuacg     2460

accaccuaga gguguucgac gggcgagacg ccaaggcccc cguccucggc cgcuucugug     2520

ggagcaagaa gcccgagccc guccuggcca caggcagccg cauguuccug cgcuucuacu     2580

cagauaacuc gguccagcga aagggcuucc aggccuccca cgccacagag ugcgggggcc     2640

agguacgggc agacgugaag accaaggacc uuuacuccca cgcccaguuu ggcgacaaca     2700

acuacccugg ggguguggac ugugaguggg ucauuguggc cgaggaaggc uacggcgugg     2760

agcucguguu ccagaccuuu gagguggagg aggagaccga cugcggcuau gacuacaugg     2820

agcucuucga cggcuacgac agcacagccc ccaggcuggg gcgcuacugu ggcucagggc     2880

cuccugagga gguguacucg gcgggagauu cuguccuggu gaaguuccac ucggaugaca     2940

ccaucaccaa aaaagguuuc caccugcgau acaccagcac caaguuccag gacacacucc     3000

acagcaggaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  2633
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (wt)

<400>  2633
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

ccgggacccg cugucuucua gcguugcugc uuccccaggu ccuccugggc ggcgcggcug      120

gccucguucc ggagcugggc cgcaggaagu ucgcggcggc gucgucgggc cgccccucau      180

cccagcccuc ugacgagguc cugagcgagu ucgaguugcg gcugcucagc auguucggcc      240

ugaaacagag acccaccccc agcagggacg ccguggugcc ccccuacaug cuagaccugu      300

aucgcaggca cucaggucag ccgggcucac ccgccccaga ccaccgguug gagagggcag      360

ccagccgagc caacacugug cgcagcuucc accaugaaga aucuuuggaa gaacuaccag      420

aaacgagugg gaaaacaacc cggagauucu ucuuuaauuu aaguucuauc cccacggagg      480

aguuuaucac cucagcagag cuucagguuu uccgagaaca gaugcaagau gcuuuaggaa      540

acaauagcag uuuccaucac cgaauuaaua uuuaugaaau cauaaaaccu gcaacagcca      600

acucgaaauu ccccgugacc agacuuuugg acaccagguu ggugaaucag aaugcaagca      660

ggugggaaag uuuugauguc acccccgcug ugaugcggug gacugcacag ggacacgcca      720

accauggauu cgugguggaa guggcccacu uggaggagaa acaagguguc uccaagagac      780

auguuaggau aagcaggucu uugcaccaag augaacacag cuggucacag auaaggccau      840

ugcuaguaac uuuuggccau gauggaaaag ggcauccucu ccacaaaaga gaaaaacguc      900

aagccaaaca caaacagcgg aaacgccuua aguccagcug uaagagacac ccuuuguacg      960

uggacuucag ugacgugggg uggaaugacu ggauuguggc ucccccgggg uaucacgccu     1020

uuuacugcca cggagaaugc ccuuuuccuc uggcugauca ucugaacucc acuaaucaug     1080

ccauuguuca gacguugguc aacucuguua acucuaagau uccuaaggca ugcugugucc     1140

cgacagaacu cagugcuauc ucgaugcugu accuugacga gaaugaaaag guuguauuaa     1200

agaacuauca ggacaugguu guggaggguu gugggugucg cuagggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  2634
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (wt)

<400>  2634
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauuc       60

cugguaaccg aaugcugaug gucguuuuau uaugccaagu ccugcuagga ggcgcgagcc      120

augcuaguuu gauaccugag acggggaaga aaaaagucgc cgagauucag ggccacgcgg      180

gaggacgccg cucagggcag agccaugagc uccugcggga cuucgaggcg acacuucugc      240

agauguuugg gcugcgccgc cgcccgcagc cuagcaagag ugccgucauu ccggacuaca      300

ugcgggaucu uuaccggcuu cagucugggg aggaggagga agagcagauc cacagcacug      360

gucuugagua uccugagcgc ccggccagcc gggccaacac cgugaggagc uuccaccacg      420

aagaacaucu ggagaacauc ccagggacca gugaaaacuc ugcuuuucgu uuccucuuua      480

accucagcag caucccugag aacgagguga ucuccucugc agagcuucgg cucuuccggg      540

agcaggugga ccagggcccu gauugggaaa ggggcuucca ccguauaaac auuuaugagg      600

uuaugaagcc cccagcagaa guggugccug ggcaccucau cacacgacua cuggacacga      660

gacuggucca ccacaaugug acacgguggg aaacuuuuga ugugagcccu gcgguccuuc      720

gcuggacccg ggagaagcag ccaaacuaug ggcuagccau ugaggugacu caccuccauc      780

agacucggac ccaccagggc cagcauguca ggauuagccg aucguuaccu caagggagug      840

ggaauugggc ccagcuccgg ccccuccugg ucaccuuugg ccaugauggc cggggccaug      900

ccuugacccg acgccggagg gccaagcgua gcccuaagca ucacucacag cgggccagga      960

agaagaauaa gaacugccgg cgccacucgc ucuaugugga cuucagcgau gugggcugga     1020

augacuggau uguggcccca ccaggcuacc aggccuucua cugccauggg gacugccccu     1080

uuccacuggc ugaccaccuc aacucaacca accaugccau ugugcagacc cuggucaauu     1140

cugucaauuc caguaucccc aaagccuguu gugugcccac ugaacugagu gccaucucca     1200

ugcuguaccu ggaugaguau gauaaggugg uacugaaaaa uuaucaggag augguaguag     1260

agggaugugg gugccgcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  2635
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (wt)

<400>  2635
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgg       60

ggcuggggcg gagggcgcag uggcugugcu gguggugggg gcugcugugc agcugcugcg      120

ggcccccgcc gcugcggccg cccuugcccg cugccgcggc cgccgccgcc ggggggcagc      180

ugcuggggga cggcgggagc cccggccgca cggagcagcc gccgccgucg ccgcaguccu      240

ccucgggcuu ccuguaccgg cggcucaaga cgcaggagaa gcgggagaug cagaaggaga      300

ucuugucggu gcuggggcuc ccgcaccggc cccggccccu gcacggccuc caacagccgc      360

agcccccggc gcuccggcag caggaggagc agcagcagca gcagcagcug ccucgcggag      420

agcccccucc cgggcgacug aaguccgcgc cccucuucau gcuggaucug uacaacgccc      480

uguccgccga caacgacgag gacggggcgu cggaggggga gaggcagcag uccuggcccc      540

acgaagcagc cagcucgucc cagcgucggc agccgccccc gggcgccgcg cacccgcuca      600

accgcaagag ccuucuggcc cccggaucug gcagcggcgg cgcgucccca cugaccagcg      660

cgcaggacag cgccuuccuc aacgacgcgg acauggucau gagcuuugug aaccuggugg      720

aguacgacaa ggaguucucc ccucgucagc gacaccacaa agaguucaag uucaacuuau      780

cccagauucc ugagggugag guggugacgg cugcagaauu ccgcaucuac aaggacugug      840

uuauggggag uuuuaaaaac caaacuuuuc uuaucagcau uuaucaaguc uuacaggagc      900

aucagcacag agacucugac cuguuuuugu uggacacccg uguaguaugg gccucagaag      960

aaggcuggcu ggaauuugac aucacggcca cuagcaaucu guggguugug acuccacagc     1020

auaacauggg gcuucagcug agcgugguga caagggaugg aguccacguc cacccccgag     1080

ccgcaggccu ggugggcaga gacggcccuu acgacaagca gcccuucaug guggcuuucu     1140

ucaaagugag ugaggugcac gugcgcacca ccaggucagc cuccagccgg cgccgacaac     1200

agagucguaa ucgcucuacc cagucccagg acguggcgcg ggucuccagu gcuucagauu     1260

acaacagcag ugaauugaaa acagccugca ggaagcauga gcuguaugug aguuuccaag     1320

accugggaug gcaggacugg aucauugcac ccaagggcua ugcugccaau uacugugaug     1380

gagaaugcuc cuucccacuc aacgcacaca ugaaugcaac caaccacgcg auugugcaga     1440

ccuugguuca ccuuaugaac cccgaguaug uccccaaacc gugcugugcg ccaacuaagc     1500

uaaaugccau cucgguucuu uacuuugaug acaacuccaa ugucauucug aaaaaauaca     1560

ggaauauggu uguaagagcu uguggaugcc acuaaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  2636
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (wt)

<400>  2636
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

ugcgcucacu gcgagcugcg gcgccgcaca gcuucguggc gcucugggca ccccuguucc      120

ugcugcgcuc cgcccuggcc gacuucagcc uggacaacga ggugcacucg agcuucaucc      180

accggcgccu ccgcagccag gagcggcggg agaugcagcg cgagauccuc uccauuuugg      240

gcuugcccca ccgcccgcgc ccgcaccucc agggcaagca caacucggca cccauguuca      300

ugcuggaccu guacaacgcc auggcggugg aggagggcgg cgggcccggc ggccagggcu      360

ucuccuaccc cuacaaggcc gucuucagua cccagggccc cccucuggcc agccugcaag      420

auagccauuu ccucaccgac gccgacaugg ucaugagcuu cgucaaccuc guggaacaug      480

acaaggaauu cuuccaccca cgcuaccacc aucgagaguu ccgguuugau cuuuccaaga      540

ucccagaagg ggaagcuguc acggcagccg aauuccggau cuacaaggac uacauccggg      600

aacgcuucga caaugagacg uuccggauca gcguuuauca ggugcuccag gagcacuugg      660

gcagggaauc ggaucucuuc cugcucgaca gccguacccu cugggccucg gaggagggcu      720

ggcugguguu ugacaucaca gccaccagca accacugggu ggucaauccg cggcacaacc      780

ugggccugca gcucucggug gagacgcugg augggcagag caucaacccc aaguuggcgg      840

gccugauugg gcggcacggg ccccagaaca agcagcccuu caugguggcu uucuucaagg      900

ccacggaggu ccacuuccgc agcauccggu ccacggggag caaacagcgc agccagaacc      960

gcuccaagac gcccaagaac caggaagccc ugcggauggc caacguggca gagaacagca     1020

gcagcgacca gaggcaggcc uguaagaagc acgagcugua ugucagcuuc cgagaccugg     1080

gcuggcagga cuggaucauc gcgccugaag gcuacgccgc cuacuacugu gagggggagu     1140

gugccuuccc ucugaacucc uacaugaacg ccaccaacca cgccaucgug cagacgcugg     1200

uccacuucau caacccggaa acggugccca agcccugcug ugcgcccacg cagcucaaug     1260

ccaucuccgu ccucuacuuc gaugacagcu ccaacgucau ccugaagaaa uacagaaaca     1320

uggugguccg ggccuguggc ugccacuagg gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  2637
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (wt)

<400>  2637
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaag       60

ccucugcagc acuucugugu cugcugcuca cagcagcugc uuucagcccc caggggcuug      120

cucagccagu ugggauuaau acuucaacua ccugcugcua cagauuuauc aauaagaaaa      180

ucccuaagca gaggcuggag agcuacagaa ggaccaccag uagccacugu ccccgggaag      240

cuguaaucuu caagaccaaa cuggacaagg agaucugugc ugaccccaca cagaaguggg      300

uccaggacuu uaugaagcac cuggacaaga aaacccaaac uccaaagcuu ugaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  2638
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (wt)

<400>  2638
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugc       60

ucacucuuau cauucuguug ccaguaguuu caaaauuuag uuuuguuagu cucucagcac      120

cgcagcacug gagcuguccu gaagguacuc ucgcaggaaa ugggaauucu acuugugugg      180

guccugcacc cuucuuaauu uucucccaug gaaauaguau cuuuaggauu gacacagaag      240

gaaccaauua ugagcaauug gugguggaug cuggugucuc agugaucaug gauuuucauu      300

auaaugagaa aagaaucuau uggguggauu uagaaagaca acuuuugcaa agaguuuuuc      360

ugaauggguc aaggcaagag agaguaugua auauagagaa aaauguuucu ggaauggcaa      420

uaaauuggau aaaugaagaa guuauuuggu caaaucaaca ggaaggaauc auuacaguaa      480

cagauaugaa aggaaauaau ucccacauuc uuuuaagugc uuuaaaauau ccugcaaaug      540

uagcaguuga uccaguagaa agguuuauau uuuggucuuc agagguggcu ggaagccuuu      600

auagagcaga ucucgauggu gugggaguga aggcucuguu ggagacauca gagaaaauaa      660

cagcuguguc auuggaugug cuugauaagc ggcuguuuug gauucaguac aacagagaag      720

gaagcaauuc ucuuauuugc uccugugauu augauggagg uucuguccac auuaguaaac      780

auccaacaca gcauaauuug uuugcaaugu cccuuuuugg ugaccguauc uucuauucaa      840

cauggaaaau gaagacaauu uggauagcca acaaacacac uggaaaggac augguuagaa      900

uuaaccucca uucaucauuu guaccacuug gugaacugaa aguagugcau ccacuugcac      960

aacccaaggc agaagaugac acuugggagc cugagcagaa acuuugcaaa uugaggaaag     1020

gaaacugcag cagcacugug ugugggcaag accuccaguc acacuugugc augugugcag     1080

agggauacgc ccuaagucga gaccggaagu acugugaaga uguuaaugaa ugugcuuuuu     1140

ggaaucaugg cuguacucuu ggguguaaaa acaccccugg auccuauuac ugcacgugcc     1200

cuguaggauu uguucugcuu ccugauggga aacgauguca ucaacuuguu uccuguccac     1260

gcaauguguc ugaaugcagc caugacugug uucugacauc agaagguccc uuauguuucu     1320

guccugaagg cucagugcuu gagagagaug ggaaaacaug uagcgguugu uccucacccg     1380

auaauggugg auguagccag cucugcguuc cucuuagccc aguauccugg gaaugugauu     1440

gcuuuccugg guaugaccua caacuggaug aaaaaagcug ugcagcuuca ggaccacaac     1500

cauuuuugcu guuugccaau ucucaagaua uucgacacau gcauuuugau ggaacagacu     1560

auggaacucu gcucagccag cagaugggaa ugguuuaugc ccuagaucau gacccugugg     1620

aaaauaagau auacuuugcc cauacagccc ugaaguggau agagagagcu aauauggaug     1680

guucccagcg agaaaggcuu auugaggaag gaguagaugu gccagaaggu cuugcugugg     1740

acuggauugg ccguagauuc uauuggacag acagagggaa aucucugauu ggaaggagug     1800

auuuaaaugg gaaacguucc aaaauaauca cuaaggagaa caucucucaa ccacgaggaa     1860

uugcuguuca uccaauggcc aagagauuau ucuggacuga uacagggauu aauccacgaa     1920

uugaaaguuc uucccuccaa ggccuuggcc gucugguuau agccagcucu gaucuaaucu     1980

ggcccagugg aauaacgauu gacuucuuaa cugacaaguu guacuggugc gaugccaagc     2040

agucugugau ugaaauggcc aaucuggaug guucaaaacg ccgaagacuu acccagaaug     2100

auguagguca cccauuugcu guagcagugu uugaggauua ugugugguuc ucagauuggg     2160

cuaugccauc aguaaugaga guaaacaaga ggacuggcaa agauagagua cgucuccaag     2220

gcagcaugcu gaagcccuca ucacugguug ugguucaucc auuggcaaaa ccaggagcag     2280

aucccugcuu auaucaaaac ggaggcugug aacauauuug caaaaagagg cuuggaacug     2340

cuugguguuc gugucgugaa gguuuuauga aagccucaga ugggaaaacg ugucuggcuc     2400

uggaugguca ucagcuguug gcagguggug aaguugaucu aaagaaccaa guaacaccau     2460

uggacaucuu guccaagacu agagugucag aagauaacau uacagaaucu caacacaugc     2520

uaguggcuga aaucauggug ucagaucaag augacugugc uccuguggga ugcagcaugu     2580

augcucggug uauuucagag ggagaggaug ccacauguca guguuugaaa ggauuugcug     2640

gggauggaaa acuauguucu gauauagaug aaugugagau ggguguccca gugugccccc     2700

cugccuccuc caagugcauc aacaccgaag gugguuaugu cugccggugc ucagaaggcu     2760

accaaggaga ugggauucac ugucuugaua uugaugagug ccaacugggg gagcacagcu     2820

guggagagaa ugccagcugc acaaauacag agggaggcua uaccugcaug ugugcuggac     2880

gccugucuga accaggacug auuugcccug acucuacucc acccccucac cucagggaag     2940

augaccacca cuauuccgua agaaauagug acucugaaug uccccugucc cacgaugggu     3000

acugccucca ugauggugug ugcauguaua uugaagcauu ggacaaguau gcaugcaacu     3060

guguuguugg cuacaucggg gagcgauguc aguaccgaga ccugaagugg ugggaacugc     3120

gccacgcugg ccacgggcag cagcagaagg ucaucguggu ggcugucugc gugguggugc     3180

uugucaugcu gcuccuccug agccuguggg gggcccacua cuacaggacu cagaagcugc     3240

uaucgaaaaa cccaaagaau ccuuaugagg agucgagcag agaugugagg agucgcaggc     3300

cugcugacac ugaggauggg auguccucuu gcccucaacc uugguuugug guuauaaaag     3360

aacaccaaga ccucaagaau gggggucaac caguggcugg ugaggauggc caggcagcag     3420

augggucaau gcaaccaacu ucauggaggc aggagcccca guuaugugga augggcacag     3480

agcaaggcug cuggauucca guauccagug auaagggcuc cuguccccag guaauggagc     3540

gaagcuuuca uaugcccucc uaugggacac agacccuuga aggggguguc gagaagcccc     3600

auucucuccu aucagcuaac ccauuauggc aacaaagggc ccuggaccca ccacaccaaa     3660

uggagcugac ucagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  2639
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (wt)

<400>  2639
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

cggggaggag gauggagaug cucugugccg gcaggguccc ugcgcugcug cucugccugg      120

guuuccaucu ucuacaggca guccucagua caacugugau uccaucaugu aucccaggag      180

aguccaguga uaacugcaca gcuuuaguuc agacagaaga caauccacgu guggcucaag      240

ugucaauaac aaaguguagc ucugacauga auggcuauug uuugcaugga cagugcaucu      300

aucuggugga caugagucaa aacuacugca ggugugaagu ggguuauacu gguguccgau      360

gugaacacuu cuuuuuaacc guccaccaac cuuuaagcaa agaauaugug gcuuugaccg      420

ugauucuuau uauuuuguuu cuuaucacag ucgucgguuc cacauauuau uucugcagau      480

gguacagaaa ucgaaaaagu aaagaaccaa agaaggaaua ugagagaguu accucagggg      540

auccagaguu gccgcaaguc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  2640
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (wt)

<400>  2640
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcug       60

aaggggaaau caccaccuuc acagcccuga ccgagaaguu uaaucugccu ccagggaauu      120

acaagaagcc caaacuccuc uacuguagca acgggggcca cuuccugagg auccuuccgg      180

auggcacagu ggaugggaca agggacagga gcgaccagca cauucagcug cagcucagug      240

cggaaagcgu gggggaggug uauauaaaga guaccgagac uggccaguac uuggccaugg      300

acaccgacgg gcuuuuauac ggcucacaga caccaaauga ggaauguuug uuccuggaaa      360

ggcuggagga gaaccauuac aacaccuaua uauccaagaa gcaugcagag aagaauuggu      420

uuguuggccu caagaagaau gggagcugca aacgcggucc ucggacucac uauggccaga      480

aagcaaucuu guuucucccc cugccagucu cuucugauua aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  2641
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (wt)

<400>  2641
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

gugugggggg uggagaugua gaagauguga cgccgcggcc cggcgggugc cagauuagcg      120

gacgcggugc ccgcgguugc aacgggaucc cgggcgcugc agcuugggag gcggcucucc      180

ccaggcggcg uccgcggaga cacccauccg ugaaccccag gucccgggcc gccggcucgc      240

cgcgcaccag gggccggcgg acagaagagc ggccgagcgg cucgaggcug ggggaccgcg      300

ggcgcggccg cgcgcugccg ggcgggaggc uggggggccg gggccggggc cgugccccgg      360

agcgggucgg aggccggggc cggggccggg ggacggcggc uccccgcgcg gcuccagcgg      420

cucggggauc ccggccgggc cccgcaggga ccauggcagc cgggagcauc accacgcugc      480

ccgccuugcc cgaggauggc ggcagcggcg ccuucccgcc cggccacuuc aaggacccca      540

agcggcugua cugcaaaaac gggggcuucu uccugcgcau ccaccccgac ggccgaguug      600

acgggguccg ggagaagagc gacccucaca ucaagcuaca acuucaagca gaagagagag      660

gaguuguguc uaucaaagga gugugugcua accguuaccu ggcuaugaag gaagauggaa      720

gauuacuggc uucuaaaugu guuacggaug aguguuucuu uuuugaacga uuggaaucua      780

auaacuacaa uacuuaccgg ucaaggaaau acaccaguug guauguggca cugaaacgaa      840

cugggcagua uaaacuugga uccaaaacag gaccugggca gaaagcuaua cuuuuucuuc      900

caaugucugc uaagagcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  2642
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (wt)

<400>  2642
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aauggauacu gacauggauc cugccaacuu ugcucuacag aucaugcuuu cacauuaucu      120

gucuaguggg uacuauaucu uuagcuugca augacaugac uccagagcaa auggcuacaa      180

augugaacug uuccagcccu gagcgacaca caagaaguua ugauuacaug gaaggagggg      240

auauaagagu gagaagacuc uucugucgaa cacaguggua ccugaggauc gauaaaagag      300

gcaaaguaaa agggacccaa gagaugaaga auaauuacaa uaucauggaa aucaggacag      360

uggcaguugg aauuguggca aucaaagggg uggaaaguga auucuaucuu gcaaugaaca      420

aggaaggaaa acucuaugca aagaaagaau gcaaugaaga uuguaacuuc aaagaacuaa      480

uucuggaaaa ccauuacaac acauaugcau cagcuaaaug gacacacaac ggaggggaaa      540

uguuuguugc cuuaaaucaa aaggggauuc cuguaagagg aaaaaaaacg aagaaagaac      600

aaaaaacagc ccacuuucuu ccuauggcaa uaacuuaagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  2643
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (wt)

<400>  2643
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ugcugccguc gguggugcug aagcucuuuc uggcugcagu ucucucggca cuggugacug      120

gcgagagccu ggagcggcuu cggagagggc uagcugcugg aaccagcaac ccggacccuc      180

ccacuguauc cacggaccag cugcuacccc uaggaggcgg ccgggaccgg aaaguccgug      240

acuugcaaga ggcagaucug gaccuuuuga gagucacuuu auccuccaag ccacaagcac      300

uggccacacc aaacaaggag gagcacggga aaagaaagaa gaaaggcaag gggcuaggga      360

agaagaggga cccaugucuu cggaaauaca aggacuucug cauccaugga gaaugcaaau      420

augugaagga gcuccgggcu cccuccugca ucugccaccc ggguuaccau ggagagaggu      480

gucaugggcu gagccuccca guggaaaauc gcuuauauac cuaugaccac acaaccaucc      540

uggccguggu ggcuguggug cugucaucug ucugucugcu ggucaucgug gggcuucuca      600

uguuuaggua ccauaggaga ggagguuaug auguggaaaa ugaagagaaa gugaaguugg      660

gcaugacuaa uucccacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  2644
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (wt)

<400>  2644
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ugaccaaacu ccugccagcc cugcugcugc agcauguccu ccugcaucuc cuccugcucc      120

ccaucgccau ccccuaugca gagggacaaa ggaaaagaag aaauacaauu caugaauuca      180

aaaaaucagc aaagacuacc cuaaucaaaa uagauccagc acugaagaua aaaaccaaaa      240

aagugaauac ugcagaccaa ugugcuaaua gauguacuag gaauaaagga cuuccauuca      300

cuugcaaggc uuuuguuuuu gauaaagcaa gaaaacaaug ccucugguuc cccuucaaua      360

gcaugucaag uggagugaaa aaagaauuug gccaugaauu ugaccucuau gaaaacaaag      420

acuacauuag aaacugcauc auugguaaag gacgcagcua caagggaaca guaucuauca      480

cuaagagugg caucaaaugu cagcccugga guuccaugau accacacgaa cacagcuuuu      540

ugccuucgag cuaucggggu aaagaccuac aggaaaacua cugucgaaau ccucgagggg      600

aagaaggggg acccuggugu uucacaagca auccagaggu acgcuacgaa gucugugaca      660

uuccucagug uucagaaguu gaaugcauga ccugcaaugg ggagaguuau cgaggucuca      720

uggaucauac agaaucaggc aagauuuguc agcgcuggga ucaucagaca ccacaccggc      780

acaaauucuu gccugaaaga uaucccgaca agggcuuuga ugauaauuau ugccgcaauc      840

ccgauggcca gccgaggcca uggugcuaua cucuugaccc ucacacccgc ugggaguacu      900

gugcaauuaa aacaugcgcu gacaauacua ugaaugacac ugauguuccu uuggaaacaa      960

cugaaugcau ccaaggucaa ggagaaggcu acaggggcac ugucaauacc auuuggaaug     1020

gaauuccaug ucagcguugg gauucucagu auccucacga gcaugacaug acuccugaaa     1080

auuucaagug caaggaccua cgagaaaauu acugccgaaa uccagauggg ucugaaucac     1140

ccugguguuu uaccacugau ccaaacaucc gaguuggcua cugcucccaa auuccaaacu     1200

gugauauguc acauggacaa gauuguuauc gugggaaugg caaaaauuau augggcaacu     1260

uaucccaaac aagaucugga cuaacauguu caauguggga caagaacaug gaagacuuac     1320

aucgucauau cuucugggaa ccagaugcaa guaagcugaa ugagaauuac ugccgaaauc     1380

cagaugauga ugcucaugga cccuggugcu acacgggaaa uccacucauu ccuugggauu     1440

auugcccuau uucucguugu gaaggugaua ccacaccuac aauagucaau uuagaccauc     1500

ccguaauauc uugugccaaa acgaaacaau ugcgaguugu aaaugggauu ccaacacgaa     1560

caaacauagg auggaugguu aguuugagau acagaaauaa acauaucugc ggaggaucau     1620

ugauaaagga gaguuggguu cuuacugcac gacaguguuu cccuucucga gacuugaaag     1680

auuaugaagc uuggcuugga auucaugaug uccacggaag aggagaugag aaaugcaaac     1740

agguucucaa uguuucccag cugguauaug gcccugaagg aucagaucug guuuuaauga     1800

agcuugccag gccugcuguc cuggaugauu uuguuaguac gauugauuua ccuaauuaug     1860

gaugcacaau uccugaaaag accaguugca guguuuaugg cuggggcuac acuggauuga     1920

ucaacuauga uggccuauua cgaguggcac aucucuauau aaugggaaau gagaaaugca     1980

gccagcauca ucgagggaag gugacucuga augagucuga aauaugugcu ggggcugaaa     2040

agauuggauc aggaccaugu gagggggauu augguggccc acuuguuugu gagcaacaua     2100

aaaugagaau gguucuuggu gucauuguuc cuggucgugg augugccauu ccaaaucguc     2160

cugguauuuu uguccgagua gcauauuaug caaaauggau acacaaaauu auuuuaacau     2220

auaagguacc acagucauag ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  2645
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (wt)

<400>  2645
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aagccgcggc gaucggcauc gaccugggca ccaccuacuc cugcgugggg guguuccaac      120

acggcaaggu ggagaucauc gccaacgacc agggcaaccg caccaccccc agcuacgugg      180

ccuucacgga caccgagcgg cucaucgggg augcggccaa gaaccaggug gcgcugaacc      240

cgcagaacac cguguuugac gcgaagcggc ugauuggccg caaguucggc gacccggugg      300

ugcagucgga caugaagcac uggccuuucc aggugaucaa cgacggagac aagcccaagg      360

ugcaggugag cuacaagggg gagaccaagg cauucuaccc cgaggagauc ucguccaugg      420

ugcugaccaa gaugaaggag aucgccgagg cguaccuggg cuacccggug accaacgcgg      480

ugaucaccgu gccggccuac uucaacgacu cgcagcgcca ggccaccaag gaugcgggug      540

ugaucgcggg gcucaacgug cugcggauca ucaacgagcc cacggccgcc gccaucgccu      600

acggccugga cagaacgggc aagggggagc gcaacgugcu caucuuugac cugggcgggg      660

gcaccuucga cguguccauc cugacgaucg acgacggcau cuucgaggug aaggccacgg      720

ccggggacac ccaccugggu ggggaggacu uugacaacag gcuggugaac cacuucgugg      780

aggaguucaa gagaaaacac aagaaggaca ucagccagaa caagcgagcc gugaggcggc      840

ugcgcaccgc cugcgagagg gccaagagga cccugucguc cagcacccag gccagccugg      900

agaucgacuc ccuguuugag ggcaucgacu ucuacacguc caucaccagg gcgagguucg      960

aggagcugug cuccgaccug uuccgaagca cccuggagcc cguggagaag gcucugcgcg     1020

acgccaagcu ggacaaggcc cagauucacg accugguccu ggucgggggc uccacccgca     1080

uccccaaggu gcagaagcug cugcaggacu ucuucaacgg gcgcgaccug aacaagagca     1140

ucaaccccga cgaggcugug gccuacgggg cggcggugca ggcggccauc cugauggggg     1200

acaaguccga gaacgugcag gaccugcugc ugcuggacgu ggcuccccug ucgcuggggc     1260

uggagacggc cggaggcgug augacugccc ugaucaagcg caacuccacc auccccacca     1320

agcagacgca gaucuucacc accuacuccg acaaccaacc cggggugcug auccaggugu     1380

acgagggcga gagggccaug acgaaagaca acaaucuguu ggggcgcuuc gagcugagcg     1440

gcaucccucc ggcccccagg ggcgugcccc agaucgaggu gaccuucgac aucgaugcca     1500

acggcauccu gaacgucacg gccacggaca agagcaccgg caaggccaac aagaucacca     1560

ucaccaacga caagggccgc cugagcaagg aggagaucga gcgcauggug caggaggcgg     1620

agaaguacaa agcggaggac gaggugcagc gcgagagggu gucagccaag aacgcccugg     1680

aguccuacgc cuucaacaug aagagcgccg uggaggauga ggggcucaag ggcaagauca     1740

gcgaggcgga caagaagaag gugcuggaca agugucaaga ggucaucucg uggcuggacg     1800

ccaacaccuu ggccgagaag gacgaguuug agcacaagag gaaggagcug gagcaggugu     1860

guaaccccau caucagcgga cuguaccagg gugccggugg ucccgggccu gggggcuucg     1920

gggcucaggg ucccaaggga gggucugggu caggccccac cauugaggag guagauuagg     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  2646
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (wt)

<400>  2646
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aagccgcggc gaucggcauc gaccugggca ccaccuacuc cugcgugggg guguuccaac      120

acggcaaggu ggagaucauc gccaacgacc agggcaaccg caccaccccc agcuacgugg      180

ccuucacgga caccgagcgg cucaucgggg augcggccaa gaaccaggug gcgcugaacc      240

cgcagaacac cguguuugac gcgaagcggc ugauuggccg caaguucggc gacccggugg      300

ugcagucgga caugaagcac uggccuuucc aggugaucaa cgacggagac aagcccaagg      360

ugcaggugag cuacaagggg gagaccaagg cauucuaccc cgaggagauc ucguccaugg      420

ugcugaccaa gaugaaggag aucgccgagg cguaccuggg cuacccggug accaacgcgg      480

ugaucaccgu gccggccuac uucaacgacu cgcagcgcca ggccaccaag gaugcgggug      540

ugaucgcggg gcucaacgug cugcggauca ucaacgagcc cacggccgcc gccaucgccu      600

acggccugga cagaacgggc aagggggagc gcaacgugcu caucuuugac cugggcgggg      660

gcaccuucga cguguccauc cugacgaucg acgacggcau cuucgaggug aaggccacgg      720

ccggggacac ccaccugggu ggggaggacu uugacaacag gcuggugaac cacuucgugg      780

aggaguucaa gagaaaacac aagaaggaca ucagccagaa caagcgagcc gugaggcggc      840

ugcgcaccgc cugcgagagg gccaagagga cccugucguc cagcacccag gccagccugg      900

agaucgacuc ccuguuugag ggcaucgacu ucuacacguc caucaccagg gcgagguucg      960

aggagcugug cuccgaccug uuccgaagca cccuggagcc cguggagaag gcucugcgcg     1020

acgccaagcu ggacaaggcc cagauucacg accugguccu ggucgggggc uccacccgca     1080

uccccaaggu gcagaagcug cugcaggacu ucuucaacgg gcgcgaccug aacaagagca     1140

ucaaccccga cgaggcugug gccuacgggg cggcggugca ggcggccauc cugauggggg     1200

acaaguccga gaacgugcag gaccugcugc ugcuggacgu ggcuccccug ucgcuggggc     1260

uggagacggc cggaggcgug augacugccc ugaucaagcg caacuccacc auccccacca     1320

agcagacgca gaucuucacc accuacuccg acaaccaacc cggggugcug auccaggugu     1380

acgagggcga gagggccaug acgaaagaca acaaucuguu ggggcgcuuc gagcugagcg     1440

gcaucccucc ggcccccagg ggcgugcccc agaucgaggu gaccuucgac aucgaugcca     1500

acggcauccu gaacgucacg gccacggaca agagcaccgg caaggccaac aagaucacca     1560

ucaccaacga caagggccgc cugagcaagg aggagaucga gcgcauggug caggaggcgg     1620

agaaguacaa agcggaggac gaggugcagc gcgagagggu gucagccaag aacgcccugg     1680

aguccuacgc cuucaacaug aagagcgccg uggaggauga ggggcucaag ggcaagauca     1740

gcgaggcgga caagaagaag guucuggaca agugucaaga ggucaucucg uggcuggacg     1800

ccaacaccuu ggccgagaag gacgaguuug agcacaagag gaaggagcug gagcaggugu     1860

guaaccccau caucagcgga cuguaccagg gugccggugg ucccgggccu ggcggcuucg     1920

gggcucaggg ucccaaggga gggucugggu caggcccuac cauugaggag guggauuagg     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  2647
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (wt)

<400>  2647
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcua       60

cugccaaggg aaucgccaua ggcaucgacc ugggcaccac cuacuccugu gugggggugu      120

uccagcacgg caagguggag aucaucgcca acgaccaggg caaccgcacc acccccagcu      180

acguggccuu cacagacacc gagcggcuca uuggggaugc ggccaagaac cagguagcaa      240

ugaaucccca gaacacuguu uuugaugcua aacgucugau cggcaggaaa uuuaaugauc      300

cuguuguaca agcagauaug aaacuuuggc cuuuucaagu gauuaaugaa ggaggcaagc      360

ccaaaguccu uguguccuac aaaggggaga auaaagcuuu cuacccugag gaaaucucuu      420

cgaugguauu gacuaaguug aaggagacug cugaggccuu uuugggccac ccugucacca      480

augcagugau uaccgugcca gccuauuuca augacucuca acgucaggcu acuaaggaug      540

caggugugau ugcuggacuu aaugugcuaa gaaucaucaa ugagcccacg gcugcugcca      600

uugccuaugg uuuagauaaa ggaggucaag gagaacgaca uguccugauu uuugaucugg      660

guggaggcac auuugaugug ucaauucuga ccauagauga ugggauuuuu gagguaaagg      720

ccacugcugg ggacacucac cugggugggg aggacuuuga caacaggcuu gugagccacu      780

ucguggagga guucaagagg aaacacaaaa aggacaucag ccagaacaag cgagccguga      840

ggcggcugcg caccgccugc gagagggcca agaggacccu gucguccagc acccaggcca      900

accuagaaau ugauucacuu uaugaaggca uugacuucua uacauccauc accagagcuc      960

gauuugaaga guugugugca gaccuguuua gggguacccu ggagccugua gaaaaagcgc     1020

uucgggaugc caagauggau aaggcuaaaa uccaugacau uguuuuagua gggggcucca     1080

cccgcauccc caaggugcag cggcugcuuc aggacuacuu caauggacgu gaucucaaca     1140

agagcaucaa cccugaugag gccguagcau auggggcugc gguacaagca gccauccuga     1200

ugggggacaa gucugagaag guacaggacc ugcugcugcu ggacguggcu ccccuguccc     1260

uggggcugga gacggcuggg ggcgugauga cugcccugau aaagcgcaac uccaccaucc     1320

ccaccaagca gacacagauu uucaccaccu acucugacaa ccaacccggg gugcugaucc     1380

agguguauga gggcgagagg gccaugacaa aggacaacaa ccugcugggg cgguuugacc     1440

ugacuggaau cccuccagca cccaggggag uuccucagau cgaggugacg uuugacauug     1500

augccaaugg uauucucaau gucacagcca cggacaagag caccggcaag gugaacaaga     1560

ucaccaucac caaugacaag ggccgccuga gcaaggagga gauugagcgc augguucugg     1620

augcugagaa auauaaagcu gaagaugagg uccagaggga gaaaauugcu gcaaagaaug     1680

ccuuagaauc cuaugcuuuu aacaugaaga guguugugag ugaugaaggu uugaagggca     1740

agauuaguga gucugauaaa aauaaaauau uggauaaaug caacgagcuc cuuucguggc     1800

uggaggucaa ucaacuggca gagaaagaug aguuugauca uaagagaaag gaauuggagc     1860

agauguguaa cccuaucauc acaaaacucu accaaggagg augcacuggg ccugccugcg     1920

gaacagggua ugugccugga aggccugcca caggccccac aauugaagaa guagauuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  2648
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (wt)

<400>  2648
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucug       60

cccguggccc ggcuaucggc aucgaccugg gcaccaccua uucgugcguc ggggucuucc      120

aacauggcaa gguggagauc aucgccaacg accagggcaa ucgcaccacc cccagcuacg      180

uggccuucac ggacaccgag cgccucaucg gcgacgccgc caagaaccag guggccauga      240

accccaccaa caccaucuuc gacgccaaga ggcugauugg acggaaauuc gaggaugcca      300

cagugcaguc ggauaugaaa cacuggccgu uccggguggu gagcgaggga ggcaagccca      360

aagugcaagu agaguacaag ggggagacca agaccuucuu cccagaggag auauccucca      420

ugguccucac gaagaugaag gagaucgcgg aagccuaccu ggggggcaag gugcacagcg      480

cggucauaac ggucccggcc uauuucaacg acucgcagcg ccaggccacc aaggacgcag      540

gcaccaucac ggggcucaau gugcugcgca ucaucaacga gcccacggcg gcggccaucg      600

ccuacggccu ggacaagaag ggcugcgcgg gcggcgagaa gaacgugcuc aucuuugacc      660

ugggcggugg cacuuucgac guguccaucc ugaccaucga ggauggcauc uucgagguga      720

aguccacggc cggcgacacc caccugggcg gugaggacuu cgacaaccgc auggugagcc      780

accuggcgga ggaguucaag cgcaagcaca agaaggacau ugggcccaac aagcgcgccg      840

ugaggcggcu gcgcaccgcu ugcgagcgcg ccaagcgcac ccugagcucg uccacgcagg      900

cgagcaucga gaucgacucg cucuacgagg gcguggacuu cuauacgucc aucacgcgcg      960

cccgcuucga ggagcucaau gccgaccucu uucgcgggac ccuggagccg guggagaagg     1020

cgcugcgcga cgccaagcug gacaagggcc agauccagga gaucgugcug gugggcggcu     1080

ccacucguau ccccaagauc cagaagcugc ugcaggauuu cuucaacggc aaggagcuga     1140

acaagagcau caaccccgac gaggcggugg ccuauggcgc cgcggugcag gcggccaucc     1200

ucaucggcga caaaucagag aaugugcagg accugcugcu acucgacgug accccguugu     1260

cgcugggcau cgagacagcu ggcgguguca ugaccccacu caucaagagg aacaccacga     1320

uccccaccaa gcagacgcag accuucacca ccuacucgga caaccagagc agcguacugg     1380

ugcagguaua cgagggcgaa cgggccauga ccaaggacaa uaaccugcug ggcaaguucg     1440

accugaccgg gauucccccu gcgccucgcg ggguccccca aaucgagguu accuucgaca     1500

uugacgccaa uggcauccuu aacguuaccg ccgccgacaa gagcaccggu aaggaaaaca     1560

aaaucaccau caccaaugac aaaggucguc ugagcaagga cgacauugac cggauggugc     1620

aggaggcgga gcgguacaaa ucggaagaug aggcgaaucg cgaccgaguc gcggccaaaa     1680

acgcccugga guccuauacc uacaacauca agcagacggu ggaagacgag aaacugaggg     1740

gcaagauuag cgagcaggac aaaaacaaga uccucgacaa gugucaggag gugaucaacu     1800

ggcucgaccg aaaccagaug gcagagaaag augaguauga acacaagcag aaagagcucg     1860

aaagaguuug caaccccauc aucagcaaac uuuaccaagg ugguccuggc ggcggcagcg     1920

gcggcggcgg uucaggagcc uccgggggac ccaccaucga agaaguggac uaaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  2649
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (wt)

<400>  2649
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucgg       60

uggugggcau agaccugggc uuccagagcu gcuacgucgc uguggcccgc gccggcggca      120

ucgagacuau cgcuaaugag uauagcgacc gcugcacgcc ggcuugcauu ucuuuugguc      180

cuaagaaucg uucaauugga gcagcagcua aaagccaggu aauuucuaau gcaaagaaca      240

caguccaagg auuuaaaaga uuccauggcc gagcauucuc ugauccauuu guggaggcag      300

aaaaaucuaa ccuugcauau gauauugugc aguugccuac aggauuaaca gguauaaagg      360

ugacauauau ggaggaagag cgaaauuuua ccacugagca agugacugcc augcuuuugu      420

ccaaacugaa ggagacagcc gaaaguguuc uuaagaagcc uguaguugac uguguuguuu      480

cgguuccuug uuucuauacu gaugcagaaa gacgaucagu gauggaugca acacagauug      540

cuggucuuaa uugcuugcga uuaaugaaug aaaccacugc aguugcucuu gcauauggaa      600

ucuauaagca ggaucuuccu gccuuagaag agaaaccaag aaauguaguu uuuguagaca      660

ugggccacuc ugcuuaucaa guuucuguau gugcauuuaa uagaggaaaa cugaaaguuc      720

uggccacugc auuugacacg acauugggag guagaaaauu ugaugaagug uuaguaaauc      780

acuucuguga agaauuuggg aagaaauaca agcuagacau uaaguccaaa auccgugcau      840

uauuacgacu cucucaggag ugugagaaac ucaagaaauu gaugagugca aaugcuucag      900

aucucccuuu gagcauugaa uguuuuauga augauguuga uguaucugga acuaugaaua      960

gaggcaaauu ucuggagaug ugcaaugauc ucuuagcuag aguggagcca ccacuucgua     1020

guguuuugga acaaaccaag uuaaagaaag aagauauuua ugcaguggag auaguuggug     1080

gugcuacacg aaucccugcg guaaaagaga agaucagcaa auuuuucggu aaagaacuua     1140

guacaacauu aaaugcugau gaagcuguca cucgaggcug ugcauugcag ugugccaucu     1200

uaucgccugc uuucaaaguc agagaauuuu cuaucacuga uguaguacca uauccaauau     1260

cucugagaug gaauucucca gcugaagaag ggucaaguga cugugaaguc uuuuccaaaa     1320

aucaugcugc uccuuucucu aaaguucuua cauuuuauag aaaggaaccu uucacucuug     1380

aggccuacua cagcucuccu caggauuugc ccuauccaga uccugcuaua gcucaguuuu     1440

caguucagaa agucacuccu cagucugaug gcuccaguuc aaaagugaaa gucaaaguuc     1500

gaguaaaugu ccauggcauu uucagugugu ccagugcauc uuuaguggag guucacaagu     1560

cugaggaaaa ugaggagcca auggaaacag aucagaaugc aaaggaggaa gagaagaugc     1620

aaguggacca ggaggaacca cauguugaag agcaacagca gcagacacca gcagaaaaua     1680

aggcagaguc ugaagaaaug gagaccucuc aagcuggauc caaggauaaa aagauggacc     1740

aaccacccca agccaagaag gcaaaaguga agaccaguac uguggaccug ccaaucgaga     1800

aucagcuauu auggcagaua gacagagaga ugcucaacuu guacauugaa aaugagggua     1860

agaugaucau gcaggauaaa cuggagaagg agcggaauga ugcuaagaac gcaguggagg     1920

aauaugugua ugaaaugaga gacaagcuua guggugaaua ugagaaguuu gugagugaag     1980

augaucguaa caguuuuacu uugaaacugg aagauacuga aaauugguug uaugaggaug     2040

gagaagacca gccaaagcaa guuuauguug auaaguuggc ugaauuaaaa aaucuagguc     2100

aaccuauuaa gauacguuuc caggaaucug aagaacgacc aaaauuauuu gaagaacuag     2160

ggaaacagau ccaacaguau augaaaauaa ucagcucuuu caaaaacaag gaggaccagu     2220

augaucauuu ggaugcugcu gacaugacaa agguagaaaa aagcacaaau gaagcaaugg     2280

aguggaugaa uaacaagcua aaucugcaga acaagcagag uuugaccaug gauccaguug     2340

ucaagucaaa agagauugaa gcuaaaauua aggagcugac aaguacuugu agcccuauaa     2400

uuucaaagcc caaacccaaa guggaaccuc caaaagagga acaaaaaaau gcagagcaga     2460

auggaccagu ggauggacaa ggagacaacc caggccccca ggcugcugag caggguacag     2520

acacagcugu gccuucggau ucagacaaga agcuuccuga aauggacauu gauugaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  2650
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (wt)

<400>  2650
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucug       60

ugguuggcau ugaccucggc uuucucaacu gcuacauugc ugucgcgaga aguggcggca      120

ucgagaccau cgccaaugag uacagcgaca gguguacccc ggccuguaua ucauugggau      180

caagaacucg agccauugga aaugcagcaa agagccagau agucacgaac guaagaaaua      240

caauucaugg cuucaaaaag cuucaugggc gaucauuuga ugaucccauu gugcaaacug      300

aaaggaucag gcuucccuau gaacugcaga aaaugccuaa uggaagugca ggaguuaagg      360

ugcgguacuu agaggaagag agaccuuuug caauugagca aguuacugga augcuguuag      420

ccaagcuuaa agagacuuca gaaaaugcuu ugaagaaacc aguggcugac ugugugauuu      480

caauuccuag cuuuuuuacu gaugccgaga gaagaucugu gauggcugca gcccagguug      540

caggcuuaaa uuguuuaagg uugaugaaug aaacuacugc aguugcacug gcguauggaa      600

uuuauaaaca ggaucuuccc ccauuagaug agaaaccaag aaauguagua uuuauugaua      660

ugggacauuc ugccuaucag gucuugguuu gugcuuuuaa caaaggaaaa cuuaaagucu      720

uggcuacuac cuuugaucca uauuugggug gcaggaacuu ugaugaggcu uuaguagacu      780

acuucuguga ugaguucaag accaaauaua agauaaaugu gaaagaaaac ucucgggccu      840

uguugcguuu auaucaggaa ugugaaaaac uaaagaagcu aaugagugca aaugcaucag      900

aucuuccauu gaacauugag uguuucauga augaccuuga uguuucuagu aaaaugaaca      960

gggcucaauu ugaacaacug ugugcuuccc uuuuggccag gguugaacca ccuuuaaaag     1020

caguaaugga acaagcuaac uuacaacgug aagacauuag uaguauagaa auuguaggag     1080

gagcaacacg aauuccugca gugaaagaac aaaucacuaa auucuuucuu aaagacauaa     1140

guaccacauu aaaugcugau gaagcuguug caagaggaug ugcguuacag ugugcgauuc     1200

ucucaccagc auuuaaagug cgugaauuuu ccauaacaga ccuuguuccc uauucaauca     1260

cauuaaggug gaagaccucu uuugaagaug gaagugggga augugaaguu uucuguaaga     1320

accauccugc cccauucuca aaagucauua cuuuccacaa gaaggaacca uuugaacuag     1380

aagcauuuua uacuaauuua caugaagugc cuuauccuga ugcaagaauu gggagcuuca     1440

cuauucagaa uguuuuucca cagucugaug gugauaguuc caaagugaag guuaaaguuc     1500

guguuaacau ccauggaauc uucagugugg cuagcgcauc aguaauugag aagcaaaauu     1560

uggaaggcga ucacagugau gcuccaaugg agacagaaac uucauuuaaa aaugaaaaca     1620

aagauaauau ggauaaaaug cagguugauc aagaagaagg gcaucaaaaa ugucaugcug     1680

aacacacucc agaagaggaa auugaucaua caggagccaa aacaaaguca gcugucucag     1740

acaaacaaga ccgauuaaau cagacacuua aaaaaggaaa agucaaaagu auugaucuac     1800

cgauccagag uagccuaugu agacaacuag gccaagaucu ucucaacagc uacauugaaa     1860

augaggggaa gaugaucaug caagauaagu uagagaaaga aagaaaugau gcuaagaaug     1920

ccguugaaga auauguauau gauuuuagag acaggcuggg cacugucuau gaaaaauuca     1980

ucacuccaga agacuugagu aaacugucug caguauugga agacacagaa aauuggcuuu     2040

augaagacgg agaggaccaa ccuaaacaag uuuaugugga uaagcuucaa gaacuaaaga     2100

aauacggcca gccuauucaa augaaguaca uggagcauga agagagacca aaagccuuaa     2160

augacuuggg aaaaaagauc caacuuguca ugaaagugau agaagcuuau agaaacaagg     2220

augaaagaua ugaucaucug gauccuacug aaauggaaaa gguugaaaaa uguaucagug     2280

augccaugag uuggcugaau aguaagauga augcacagaa caaacuaagu cucacucaag     2340

auccuguggu aaaaguuuca gaaauaguag caaagucaaa ggaacuggau aauuucugua     2400

accccaucau uuacaagccc aaaccaaaag cagaaguucc ugaagacaaa ccaaaagcua     2460

auagugaaca caauggccca auggauggac agaguggaac ugaaacuaaa ucagauucaa     2520

caaaagacag cucacagcau acuaaauccu cuggagagau ggaaguggac uaaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  2651
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (wt)

<400>  2651
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ucucccuggu ggccgcgaug cugcugcugc ucagcgcggc gcgggccgag gaggaggaca      120

agaaggagga cgugggcacg guggucggca ucgaccuggg gaccaccuac uccugcgucg      180

gcguguucaa gaacggccgc guggagauca ucgccaacga ucagggcaac cgcaucacgc      240

cguccuaugu cgccuucacu ccugaagggg aacgucugau uggcgaugcc gccaagaacc      300

agcucaccuc caaccccgag aacacggucu uugacgccaa gcggcucauc ggccgcacgu      360

ggaaugaccc gucugugcag caggacauca aguucuugcc guucaaggug guugaaaaga      420

aaacuaaacc auacauucaa guugauauug gaggugggca aacaaagaca uuugcuccug      480

aagaaauuuc ugccaugguu cucacuaaaa ugaaagaaac cgcugaggcu uauuugggaa      540

agaagguuac ccaugcaguu guuacuguac cagccuauuu uaaugaugcc caacgccaag      600

caaccaaaga cgcuggaacu auugcuggcc uaaauguuau gaggaucauc aacgagccua      660

cggcagcugc uauugcuuau ggccuggaua agagggaggg ggagaagaac auccuggugu      720

uugaccuggg uggcggaacc uucgaugugu cucuucucac cauugacaau ggugucuucg      780

aaguuguggc cacuaaugga gauacucauc uggguggaga agacuuugac cagcguguca      840

uggaacacuu caucaaacug uacaaaaaga agacgggcaa agaugucagg aaagacaaua      900

gagcugugca gaaacuccgg cgcgagguag aaaaggccaa acgggcccug ucuucucagc      960

aucaagcaag aauugaaauu gaguccuucu augaaggaga agacuuuucu gagacccuga     1020

cucgggccaa auuugaagag cucaacaugg aucuguuccg gucuacuaug aagcccgucc     1080

agaaaguguu ggaagauucu gauuugaaga agucugauau ugaugaaauu guucuuguug     1140

guggcucgac ucgaauucca aagauucagc aacugguuaa agaguucuuc aauggcaagg     1200

aaccaucccg uggcauaaac ccagaugaag cuguagcgua uggugcugcu guccaggcug     1260

gugugcucuc uggugaucaa gauacaggug accugguacu gcuugaugua uguccccuua     1320

cacuugguau ugaaacugug ggagguguca ugaccaaacu gauuccaagg aacacagugg     1380

ugccuaccaa gaagucucag aucuuuucua cagcuucuga uaaucaacca acuguuacaa     1440

ucaaggucua ugaaggugaa agaccccuga caaaagacaa ucaucuucug gguacauuug     1500

aucugacugg aauuccuccu gcuccucgug gggucccaca gauugaaguc accuuugaga     1560

uagaugugaa ugguauucuu cgagugacag cugaagacaa ggguacaggg aacaaaaaua     1620

agaucacaau caccaaugac cagaaucgcc ugacaccuga agaaaucgaa aggaugguua     1680

augaugcuga gaaguuugcu gaggaagaca aaaagcucaa ggagcgcauu gauacuagaa     1740

augaguugga aagcuaugcc uauucucuaa agaaucagau uggagauaaa gaaaagcugg     1800

gagguaaacu uuccucugaa gauaaggaga ccauggaaaa agcuguagaa gaaaagauug     1860

aauggcugga aagccaccaa gaugcugaca uugaagacuu caaagcuaag aagaaggaac     1920

uggaagaaau uguucaacca auuaucagca aacucuaugg aagugcaggc ccucccccaa     1980

cuggugaaga ggauacagca gaaaaagaug aguuguaggg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  2652
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (wt)

<400>  2652
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

ccccacggga gcucgcggug ggcaucgacc ugggcaccac cuacucgugc gugggcgugu      120

uucagcaggg ccgcguggag auccuggcca acgaccaggg caaccgcacc acgcccagcu      180

acguggccuu caccgacacc gagcggcugg ucggggacgc ggccaagagc caggcggccc      240

ugaaccccca caacaccgug uucgaugcca agcggcugau cgggcgcaag uucgcggaca      300

ccacggugca gucggacaug aagcacuggc ccuuccgggu ggugagcgag ggcggcaagc      360

ccaaggugcg cguaugcuac cgcggggagg acaagacguu cuaccccgag gagaucucgu      420

ccauggugcu gagcaagaug aaggagacgg ccgaggcgua ccugggccag cccgugaagc      480

acgcagugau caccgugccc gccuauuuca augacucgca gcgccaggcc accaaggacg      540

cgggggccau cgcggggcuc aacguguugc ggaucaucaa ugagcccacg gcagcugcca      600

ucgccuaugg gcuggaccgg cggggcgcgg gagagcgcaa cgugcucauu uuugaccugg      660

gugggggcac cuucgaugug ucgguucucu ccauugacgc uggugucuuu gaggugaaag      720

ccacugcugg agauacccac cugggaggag aggacuucga caaccggcuc gugaaccacu      780

ucauggaaga auuccggcgg aagcauggga aggaccugag cgggaacaag cgugcccugc      840

gcaggcugcg cacagccugu gagcgcgcca agcgcacccu guccuccagc acccaggcca      900

cccuggagau agacucccug uucgagggcg uggacuucua cacguccauc acucgugccc      960

gcuuugagga acugugcuca gaccucuucc gcagcacccu ggagccggug gagaaggccc     1020

ugcgggaugc caagcuggac aaggcccaga uucaugacgu cguccuggug gggggcucca     1080

cacgcauccc caaggugcag aaguugcugc aggacuucuu caacggcaag gagcugaaca     1140

agagcaucaa cccugaugag gcuguggccu auggggcugc ugugcaggcg gccguguuga     1200

ugggggacaa augugagaaa gugcaggauc uccugcugcu ggauguggcu ccccugucuc     1260

uggggcugga gacagcaggu ggggugauga ccacgcugau ccagaggaac gccacuaucc     1320

ccaccaagca gacccagacu uucaccaccu acucggacaa ccagccuggg gucuucaucc     1380

agguguauga gggugagagg gccaugacca aggacaacaa ccugcugggg cguuuugaac     1440

ucaguggcau cccuccugcc ccacguggag ucccccagau agaggugacu uuugacauug     1500

augcuaaugg cauccugagc gugacagcca cugacaggag cacagguaag gcuaacaaga     1560

ucaccaucac caaugacaag ggccggcuga gcaaggagga gguggagagg augguucaug     1620

aagccgagca guacaaggcu gaggaugagg cccagaggga cagaguggcu gccaaaaacu     1680

cgcuggaggc ccaugucuuc caugugaaag guucuuugca agaggaaagc cuuagggaca     1740

agauucccga agaggacagg cgcaaaaugc aagacaagug ucgggaaguc cuugccuggc     1800

uggagcacaa ccagcuggca gagaaggagg aguaugagca ucagaagagg gagcuggagc     1860

aaaucugucg ccccaucuuc uccaggcucu auggggggcc uggugucccu gggggcagca     1920

guuguggcac ucaagcccgc cagggggacc ccagcaccgg ccccaucauu gaggagguug     1980

auugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  2653
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (wt)

<400>  2653
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

ccccacggga gcucgcggug ggcaucgacc ugggcaccac cuacucgugc gugggcgugu      120

uucagcaggg ccgcguggag auccuggcca acgaccaggg caaccgcacc acgcccagcu      180

acguggccuu caccgacacc gagcggcugg ucggggacgc ggccaagagc caggcggccc      240

ugaaccccca caacaccgug uucgaugcca agcggcugau cgggcgcaag uucgcggaca      300

ccacggugca gucggacaug aagcacuggc ccuuccaggu ggugagcgag ggcggcaagc      360

ccaaggugcg cguaugcuac cgcggggagg acaagacguu cuaccccgag gagaucucgu      420

ccauggugcu gagcaagaug aaggagacgg ccgaggcgua ccugggccag cccgugaagc      480

acgcagugau caccgugccc accuauuuca guaacucgca gcgccaggcc accaaggacg      540

cgggggccau cgcggggcuc aaggugcugc cgaucaucaa ugaggccacg gcagcagcca      600

ucgccuaugg gcuggaccgg cggggcgcgg gaaagcgcaa cgugcucauu uuugaccugg      660

gugggggcac cuucgaugug ucgguucucu ccauugacgc cggugucuuu gaggugaaag      720

ccacugcugg agauacccac cugggaggag aggacuucga caaccggcuc gugaaccacu      780

ucauggaaga auuccggcgg aagcauggga aggaccugag cgggaacaag cgugcccugc      840

gcaggcugcg cacagccugu gagcgcgcca agcgcacccc guccuccagc acccaggcca      900

cccuggagau agacucccug uucgagggcg uggacuucua caaguccauc acucgugccc      960

gcuuugagga acugugcuca gaccucuucc gcagcacccu ggagccggug gagaaggccc     1020

ugcgggaugc caagcuggac aaggcccaga uucaugacuu cguccugggg ggagggcucc     1080

acucgcaucc ccaaggugca gaaguugcug caggacuucu ucaacggcaa ggagcugaac     1140

aagagcauca acccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  2654
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (wt)

<400>  2654
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucca       60

agggaccugc aguugguauu gaucuuggca ccaccuacuc uugugugggu guuuuccagc      120

acggaaaagu cgagauaauu gccaaugauc agggaaaccg aaccacucca agcuaugucg      180

ccuuuacgga cacugaacgg uugaucggug augccgcaaa gaaucaaguu gcaaugaacc      240

ccaccaacac aguuuuugau gccaaacguc ugauuggacg cagauuugau gaugcuguug      300

uccagucuga uaugaaacau uggcccuuua ugguggugaa ugaugcuggc aggcccaagg      360

uccaaguaga auacaaggga gagaccaaaa gcuucuaucc agaggaggug ucuucuaugg      420

uucugacaaa gaugaaggaa auugcagaag ccuaccuugg gaagacuguu accaaugcug      480

uggucacagu gccagcuuac uuuaaugacu cucagcguca ggcuaccaaa gaugcuggaa      540

cuauugcugg ucucaaugua cuuagaauua uuaaugagcc aacugcugcu gcuauugcuu      600

acggcuuaga caaaaagguu ggagcagaaa gaaacgugcu caucuuugac cugggaggug      660

gcacuuuuga ugugucaauc cucacuauug aggauggaau cuuugagguc aagucuacag      720

cuggagacac ccacuugggu ggagaagauu uugacaaccg aauggucaac cauuuuauug      780

cugaguuuaa gcgcaagcau aagaaggaca ucagugagaa caagagagcu guaagacgcc      840

uccguacugc uugugaacgu gcuaagcgua cccucucuuc cagcacccag gccaguauug      900

agaucgauuc ucucuaugaa ggaaucgacu ucuauaccuc cauuacccgu gcccgauuug      960

aagaacugaa ugcugaccug uuccguggca cccuggaccc aguagagaaa gcccuucgag     1020

augccaaacu agacaaguca cagauucaug auauuguccu gguugguggu ucuacucgua     1080

uccccaagau ucagaagcuu cuccaagacu ucuucaaugg aaaagaacug aauaagagca     1140

ucaacccuga ugaagcuguu gcuuauggug cagcugucca ggcagccauc uugucuggag     1200

acaagucuga gaauguucaa gauuugcugc ucuuggaugu cacuccucuu ucccuuggua     1260

uugaaacugc ugguggaguc augacugucc ucaucaagcg uaauaccacc auuccuacca     1320

agcagacaca gaccuucacu accuauucug acaaccagcc uggugugcuu auucagguuu     1380

augaaggcga gcgugccaug acaaaggaua acaaccugcu uggcaaguuu gaacucacag     1440

gcauaccucc ugcaccccga gguguuccuc agauugaagu cacuuuugac auugaugcca     1500

augguauacu caaugucucu gcuguggaca agaguacggg aaaagagaac aagauuacua     1560

ucacuaauga caagggccgu uugagcaagg aagacauuga acguaugguc caggaagcug     1620

agaaguacaa agcugaagau gagaagcaga gggacaaggu gucauccaag aauucacuug     1680

aguccuaugc cuucaacaug aaagcaacug uugaagauga gaaacuucaa ggcaagauua     1740

acgaugagga caaacagaag auucuggaca aguguaauga aauuaucaac uggcuugaua     1800

agaaucagac ugcugagaag gaagaauuug aacaucaaca gaaagagcug gagaaaguuu     1860

gcaaccccau caucaccaag cuguaccaga gugcaggagg caugccagga ggaaugccug     1920

ggggauuucc ugguggugga gcuccucccu cugguggugc uuccucaggg cccaccauug     1980

aagagguuga uuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  2655
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (wt)

<400>  2655
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauaa       60

gugccagccg agcugcagca gcccgucucg ugggcgccgc agccucccgg ggcccuacgg      120

ccgcccgcca ccaggauagc uggaauggcc uuagucauga ggcuuuuaga cuuguuucaa      180

ggcgggauua ugcaucagaa gcaaucaagg gagcaguugu ugguauugau uuggguacua      240

ccaacuccug cguggcaguu auggaaggua aacaagcaaa ggugcuggag aaugccgaag      300

gugccagaac caccccuuca guuguggccu uuacagcaga uggugagcga cuuguuggaa      360

ugccggccaa gcgacaggcu gucaccaacc caaacaauac auuuuaugcu accaagcguc      420

ucauuggccg gcgauaugau gauccugaag uacagaaaga cauuaaaaau guucccuuua      480

aaauuguccg ugccuccaau ggugaugccu ggguugaggc ucaugggaaa uuguauucuc      540

cgagucagau uggagcauuu guguugauga agaugaaaga gacugcagaa aauuacuugg      600

ggcacacagc aaaaaaugcu gugaucacag ucccagcuua uuucaaugac ucgcagagac      660

aggccacuaa agaugcuggc cagauaucug gacugaaugu gcuucgggug auuaaugagc      720

ccacagcugc ugcucuugcc uauggucuag acaaaucaga agacaaaguc auugcuguau      780

augauuuagg ugguggaacu uuugauauuu cuauccugga aauucagaaa ggaguauuug      840

aggugaaauc cacaaauggg gauaccuucu uaggugggga agacuuugac caggccuugc      900

uacggcacau ugugaaggag uucaagagag agacaggggu ugauuugacu aaagacaaca      960

uggcacuuca gaggguacgg gaagcugcug aaaaggcuaa augugaacuc uccucaucug     1020

ugcagacuga caucaauuug cccuaucuua caauggauuc uucuggaccc aagcauuuga     1080

auaugaaguu gacccgugcu caauuugaag ggauugucac ugaucuaauc agaaggacua     1140

ucgcuccaug ccaaaaagcu augcaagaug cagaagucag caagagugac auaggagaag     1200

ugauucuugu ggguggcaug acuaggaugc ccaagguuca gcagacugua caggaucuuu     1260

uuggcagagc cccaaguaaa gcugucaauc cugaugaggc uguggccauu ggagcugcca     1320

uucagggagg uguguuggcc ggcgauguca cggaugugcu gcuccuugau gucacucccc     1380

ugucucuggg uauugaaacu cuaggaggug ucuuuaccaa acuuauuaau aggaauacca     1440

cuauuccaac caagaagagc cagguauucu cuacugccgc ugauggucaa acgcaagugg     1500

aaauuaaagu gugucagggu gaaagagaga uggcuggaga caacaaacuc cuuggacagu     1560

uuacuuugau uggaauucca ccagccccuc guggaguucc ucagauugaa guuacauuug     1620

acauugaugc caaugggaua guacauguuu cugcuaaaga uaaaggcaca ggacgugagc     1680

agcagauugu aauccagucu ucugguggau uaagcaaaga ugauauugaa aauaugguua     1740

aaaaugcaga gaaauaugcu gaagaagacc ggcgaaagaa ggaacgaguu gaagcaguua     1800

auauggcuga aggaaucauu cacgacacag aaaccaagau ggaagaauuc aaggaccaau     1860

uaccugcuga ugagugcaac aagcugaaag aagagauuuc caaaaugagg gagcuccugg     1920

cuagaaaaga cagcgaaaca ggagaaaaua uuagacaggc agcauccucu cuucagcagg     1980

caucacugaa gcuguucgaa auggcauaca aaaagauggc aucugagcga gaaggcucug     2040

gaaguucugg cacuggggaa caaaaggaag aucaaaagga ggaaaaacag uaaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  2656
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (wt)

<400>  2656
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcgg       60

acaaggaggc cggcggcagc gacgggcccc gagaaacggc ucccacaucu gcauauucau      120

cuccagcccg gagucuuggg gacacaggaa uaacgccucu gucccccucc cauauuguga      180

acgacacuga cuccaacguc ucagaacagc agucauuucu cgugguggug gccgucgacu      240

uugggaccac auccaguggc uaugccuaca gcuucaccaa ggagccggaa ugcauccaug      300

ugaugaggcg augggaggga ggugacccug guguguccaa ucagaagacu ccaaccacca      360

ucuugcugac ucccgagagg aaguuccaca gcuucgggua ugccgccagg gacuuuuacc      420

augaccugga ucccaaugag gccaagcagu ggcuguaccu ggagaaguuc aagaugaagc      480

ugcacaccac uggggaccuc accauggaua cagaccugac ggcagcaaau ggcaagaaag      540

ucaaagcccu ugaaaucuuu gcuuaugccc ugcaguacuu uaaggagcag gcgcugaagg      600

agcugaguga ccaggcgggu ucggaguucg agaacucuga ugucagaugg gucaucacgg      660

ugccugccau cuggaagcag ccggccaagc aguucaugag acaagcugcc uaccaggcag      720

gccuggccuc ccccgagaac ucggagcagc ucaucauugc cuuggagccu gaggcagccu      780

cuaucuacug ccgaaagcug cggcuacacc agaugauuga gcugagcagc aaggcagccg      840

ucaaugggua cagcggcagu gacacaguag gagcuggguu uacacaggcu aaggaacaca      900

uacggcguaa ucggcagagu cggaccuuuu ugguggagaa ugucauagga gaaaucuggu      960

ccgagcugga ggaaggugau aaguaugugg uuguggacag uggcgguggc accguagacc     1020

ugacagucca ucagauccgg uuaccggagg gacaccuuaa ggaacuguau aaagcaacag     1080

gcggacccua uggaucuuua ggaguagauu augaguucga aaaacuucug uauaaaauau     1140

uuggagagga uuuuauugaa caauucaaaa ucaaacgccc ugcagccugg guugacuuaa     1200

ugauugcguu ugagucucgc aaaagggcgg cugccccaga cagaacuaac ccgcugaaca     1260

ucacccugcc cuucuccuuc auugacuacu acaagaaguu ccgcgggcac aguguggagc     1320

acgccuugcg gaaaagcaau guggauuuug ugaagugguc cucgcagggg augcugcgga     1380

ugaguccaga ugccaugaac gcccuuuuua agccgaccau cgauagcauc auugagcauc     1440

uccgggaccu guuucagaag cccgaggugu ccaccgucaa guuccucuuu cuggugggcg     1500

gcuuugccga ggcgccccug cugcagcagg cggugcaggc ugcuuuuggg gaccagugcc     1560

ggaucaucau cccccaggac gugggccuca ccauccucaa gggugccguc cucuuuggcc     1620

uggaccccgc ggucaucaag gugcgccggu cgccgcucac cuacggggua ggcgugcuga     1680

accgcuacgu ggagggcaag cacccgccug agaagcugcu ggugaaggau ggcacucggu     1740

ggugcaccga cgucuuugac aaguucaucu cugccgacca gucuguggcu cugggugagc     1800

uggucaagcg uagcuacacc ccggccaagc ccucccagcu ggucauuguc aucaacaucu     1860

acagcucuga gcacgacaac gucagcuuca ucacugaucc cggggugaag aaguguggca     1920

cgcuccgccu ggaucucaca gggaccagug gcacugcggu gcccgcccgg agggagaucc     1980

agacccuuau gcaguucggg gacaccgaga ucaaagccac agccauugau auagccacuu     2040

cgaagagugu caaaguuggg aucgacuucu uaaauuacua aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  2657
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (wt)

<400>  2657
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguugg       60

cugucccgga gaugggccug caggggcugu acaucggcuc cagcccggag cgguccccag      120

ugccuagccc acccggcucc ccgaggaccc aggaaagcug cggcauugcc ccccucacac      180

ccucgcaguc uccaaaaccc gagguccgag ccccccagca ggccuccuuc ucuguggugg      240

uggccauuga cuucggcacc acgucuagug gcuaugcuuu cagcuuugcc agugacccug      300

aggccaucca caugaugagg aaaugggagg gcggagaccc gggcguggcc caccagaaga      360

ccccgaccug ccugcugcug acuccggagg gcgccuucca cagcuuuggc uacaccgccc      420

gcgauuacua ccaugaccug gaccccgaag aggcgcggga cuggcucuac uucgagaagu      480

ucaagaugaa gauccacagc gccacggauc ucaccuugaa gacccagcua gaggcaguaa      540

auggaaagac gaugcccgcc cuggaggugu ucgcccaugc ccugcgcuuc uucagggagc      600

acgcccuuca ggagcugagg gagcagagcc caucgcugcc agagaaggac acugugcgcu      660

ggguguugac ggugccugcc aucuggaaac agccagccaa gcaguucaug cgggaggcug      720

ccuaccuggc uggacuagug ucccgagaga augcagagca gcuacucauc gcccuggagc      780

ccgaggccgc cucgguauac ugccgcaagc ugcgccugca ccagcuccug gaccugagug      840

gccgggcccc aggugguggg cgccugggug agcgccgcuc caucgacucc agcuuccguc      900

aggcucggga gcagcugcga aggucccgcc acagccgcac guuccuggug gagucaggcg      960

uaggagagcu gugggcagag augcaagcag gagaccgcua cgugguggcc gacugcggcg     1020

gaggcaccgu ggaccugacg gugcaccagc uggagcagcc ccauggcacc cucaaggagc     1080

ucuacaaggc aucugggggc ccuuauggcg cggugggcgu ggaccuggcc uucgagcagc     1140

ugcugugccg caucuucggc gaggacuuca ucgccaccuu caaaaggcaa cggccggcag     1200

ccuggguaga ucugaccauc gccuucgagg cucgcaagcg cacugcuggc ccacaccgug     1260

caggggcgcu caacaucucg cugcccuucu ccuucauuga cuucuaccgc aagcagcggg     1320

gccacaacgu ggagaccgcu cugcgcagga gcagcgugaa cuucgugaag ugguccucac     1380

aggggaugcu ccgaaugucu ugugaagcca ugaacgagcu cuuucagccc accgucagcg     1440

ggaucaucca gcacauagag gcccugcugg cacggccgga ggugcagggu gugaagcugc     1500

uguuccuagu gggcggcuuc gccgagucag cggugcugca gcacgcggug caggcggcgc     1560

ugggcgcccg cggucugcgu gucguggucc cgcacgacgu gggccucacc auccucaaag     1620

gcgcggugcu guucggccag gcgccgggcg uggugcgggu ccgccgcucg ccgcucaccu     1680

auggcguggg cgugcucaac cgcuuugugc cugggcgcca cccgcccgaa aagcugcugg     1740

uucgcgacgg ccgccgcugg ugcaccgacg ucuucgagcg cuucguggcc gccgagcagu     1800

cgguggcccu gggcgaggag gugcggcgca gcuacugccc ggcgcguccc ggccagcggc     1860

gcguacucau caaccuguac ugcugcgcgg cagaggaugc gcgcuucauc accgaccccg     1920

gcgugcgcaa augcggcgcg cucagccucg agcuugagcc cgccgacugc ggccaggaca     1980

ccgccggcgc gccucccggc cgccgcgaga uccgcgccgc caugcaguuu ggcgacaccg     2040

aaauuaaggu caccgccguc gacgucagca ccaaucgcuc cgugcgcgcg uccaucgacu     2100

uucuuuccaa cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  2658
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (wt)

<400>  2658
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

gagagaugac gaucuuagga ucggcuguuu ugacucuccu guuggccggc uauuuggcac      120

aacaguauuu accauugccu acuccuaaag ugauugguau ugaucuuggc accaccuauu      180

guucuguugg gguguuuuuu ccuggcacag gaaaaguaaa ggugauucca gaugaaaaug      240

ggcauaucag cauacccagc auggugucuu uuacugacaa ugauguauau gugggauaug      300

aaagcguaga gcuggcagau ucaaauccuc aaaacacaau auaugaugcc aaaagauuca      360

uaggcaagau uuuuaccgca gaagaguugg aggcugaaau uggcagauac ccauuuaagg      420

uuuuaaacaa aaauggaaug guugaguuuu cugugacaag uaaugagacc aucacagugu      480

ccccagaaua uguuggcucu cgacuauugu ugaaguuaaa ggaaauggca gaggcauauc      540

uuggaaugcc aguugccaau gcugucauuu cuguaccagc agaauuugau cuaaaacaga      600

gaaauucaac aauugaagcu gcuaaccuug caggacugaa gauuuugagg guaauaaaug      660

aacccacagc agcagcuaug gccuaugguc uccacaaggc ugacgucuuc cacgucuugg      720

ugauagacuu gggcggagga acucuagaug ugucuuuacu gaauaaacaa ggagggaugu      780

uucuaacccg agcaaugucu ggaaacaaua aacuuggagg acaggacuuc aaucagagau      840

ugcuucagua cuuauauaaa cagaucuauc aaacauaugg cuucgugccc ucuaggaaag      900

aggaaaucca cagauugaga caagcugugg aaauggucaa auuaaaucug acucuucauc      960

aaucugcuca guugucagua uuacuaacgg uggaggagca ggacaggaag gaaccucaca     1020

guagugacac ugaacugcca aaagacaaac uuuccucagc agaugaccau cgcgugaaca     1080

guggguuugg acguggccuu ucugauaaga aaaguggaga aagucagguu uuauuugaaa     1140

cagaaauauc acggaaacuc uuugauaccc uuaaugaaga ccucuuucag aaaauacugg     1200

uacccauuca gcaaguauug aaagaaggcc accuggaaaa gacugagauu gaugaggugg     1260

uuuuaguugg gggcuccacu cguauuccuc ggauccguca agucauucaa gaguucuuug     1320

gaaaagaucc caacacaucu guagacccug accuagcagu aguaacggga guggcuaucc     1380

aagcagggau ugauggaggc ucuuggccuc uccaagucag ugcuuuagaa auucccaaua     1440

agcauuuaca aaaaaccaac uucaacugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  2659
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (wt)

<400>  2659
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcgg       60

ccaucggagu ucaccugggc ugcaccucag ccuguguggc cgucuauaag gauggccggg      120

cugguguggu ugcaaaugau gccggugacc gaguuacucc agcuguuguu gcuuacucag      180

aaaaugaaga gauuguugga uuggcagcaa aacaaaguag aauaagaaau auuucaaaua      240

caguaaugaa aguaaagcag auccugggca gaagcuccag ugauccacaa gcucagaaau      300

acaucgcgga aaguaaaugu uuagucauug aaaaaaaugg gaaauuacga uaugaaauag      360

auacuggaga agaaacaaaa uuuguuaacc cagaagaugu ugccagacug auauuuagua      420

aaaugaaaga aacggcacau ucuguauugg gcucagaugc aaaugaugua guuauuacug      480

ucccguuuga uuuuggagaa aagcaaaaaa augcucuugg agaagcagcu agagcugcug      540

gauuuaaugu uuugcgauua auucacgaac cgucugcagc ucuucuugcu uauggaauug      600

gacaagacuc cccuacugga aaaagcaaua uuuugguguu uaagcuugga ggaacauccu      660

uaucucucag cgucauggaa guuaacagug gaauauaucg gguucuuuca acaaacacug      720

augauaacau cgguggugca cauuucacag aaaccuuagc acaguaucua gcuucugagu      780

uccaaagauc cuucaaacau gaugugagag gaaaugcgcg agccaugaug aaauuaacga      840

acagugcuga aguagcgaaa cauucuuugu caaccuuggg aagugccaac uguuuucuug      900

acucauuaua ugaaggucaa gauuuugauu gcaauguguc cagagcaaga uuugaacuuc      960

uuuguucucc acuuuuuaau aaguguauag aagcaaucag aggacucuua gaucaaaaug     1020

gauuuacagc agaugauauc aacaagguug uccuuugugg agggucuucu cgaaucccaa     1080

agcuacagca acugauuaaa gaucuuuucc cagcuguuga gcuucucaau ucuaucccuc     1140

cugaugaagu gaucccuauu ggugcagcua uagaagcagg aauucuuauu gggaaagaaa     1200

accuguuggu ggaagacucu cuuaugauag aguguucagc cagagauauu uuaguuaagg     1260

guguggacga aucaggagcc aguagauuca cagugcuguu uccaucaggg acuccuuugc     1320

cagcucgaag acaacacaca uugcaagccc cuggaagcau aucuucagug ugccuugaac     1380

ucuaugaguc ugaugggaag aacucugcca aagaggaaac caaguuugca cagguuguac     1440

uccaggauuu agauaaaaaa gaaaauggau uacgugauau auuagcuguu cuuacuauga     1500

aaagggaugg aucuuuacau gugacaugca cagaucaaga aacuggaaaa ugugaagcaa     1560

ucucuauuga gauagcaucu uagggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  2660
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (wt)

<400>  2660
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucgg       60

uggugggguu ggacgugggc ucgcagagcu gcuacaucgc gguagcccgg gccgggggca      120

ucgagaccau cgccaaugag uucagcgacc ggugcacccc gucagucaua ucauuuggau      180

caaaaaauag aacaaucgga guugcagcca aaaaucagca aaucacucau gcaaacaaua      240

cggugucuaa cuucaaaaga uuucauggcc gagcauucaa ugaccccuuc auucaaaagg      300

agaaggaaaa cuugaguuac gauuugguuc cauugaaaaa ugguggaguu ggaauaaagg      360

uaauguacau gggugaagaa caucuauuua guguggagca gauaacagcc auguuguuga      420

cuaagcugaa ggaaacugcu gaaaacagcc ucaagaaacc aguaacagau uguguuauuu      480

caguccccuc cuucuuuaca gaugcugaga ggcgaucugu guuagaugcu gcacagauug      540

uuggccuaaa cuguuuaaga cuuaugaaug acaugacagc uguugcuuug aauuacggaa      600

uuuauaagca ggaucuccca agccuggaug agaaaccucg gauagugguu uuuguugaua      660

ugggacauuc agcuuuucaa gugucugcuu gugcuuuuaa caagggaaaa uugaagguac      720

ugggaacagc uuuugauccu uucuuaggag gaaaaaacuu cgaugaaaag uuaguggaac      780

auuuuugugc agaauuuaaa acuaaguaca aguuggaugc aaaauccaaa auacgagcac      840

uccuacgucu guaucaggaa ugugaaaaac ugaaaaagcu aaugagcucu aacagcacag      900

accuuccacu gaauaucgaa ugcuuuauga augauaaaga uguuuccgga aagaugaaca      960

ggucacaauu ugaagaacuc ugugcugaac uucugcaaaa gauagaagua ccccuuuauu     1020

cacuguugga acaaacucau cucaaaguag aagaugugag ugcaguugag auuguuggag     1080

gcgcuacacg aauuccagcu gugaaggaaa gaauugccaa auucuuugga aaagauauua     1140

gcacaacacu caaugcagau gaagcaguag ccagaggaug ugcauuacag ugugcaauac     1200

uuuccccggc auuuaaaguu agagaauuuu ccgucacaga ugcaguuccu uuuccaauau     1260

cucugaucug gaaccaugau ucagaagaua cugaaggugu ucaugaaguc uuuagucgaa     1320

accaugcugc uccuuucucc aaaguucuca ccuuucugag aagggggccu uuugagcuag     1380

aagcuuucua uucugauccc caaggaguuc cauauccaga agcaaaaaua ggccgcuuug     1440

uaguucagaa uguuucugca cagaaagaug gagaaaaauc uagaguaaaa gucaaagugc     1500

gagucaacac ccauggcauu uucaccaucu cuacggcauc uaugguggag aaagucccaa     1560

cugaggagaa ugaaaugucu ucugaagcug acauggagug ucugaaucag agaccaccag     1620

aaaacccaga cacugauaaa aauguccagc aagacaacag ugaagcugga acacagcccc     1680

agguacaaac ugaugcucaa caaaccucac agucuccccc uucaccugaa cuuaccucag     1740

aagaaaacaa aaucccagau gcugacaaag caaaugaaaa aaaaguugac cagccuccag     1800

aagcuaaaaa gcccaaaaua aaggugguga auguugagcu gccuauugaa gccaacuugg     1860

ucuggcaguu agggaaagac cuucuuaaca uguauauuga gacagagggu aagaugauaa     1920

ugcaagauaa auuggaaaaa gaaaggaaug augcuaaaaa ugcaguugag gaauaugugu     1980

augaguucag agacaagcug uguggaccau augaaaaauu uauaugugag caggaucauc     2040

aaaauuuuuu gagacuccuc acagaaacug aagacuggcu guaugaagaa ggagaggacc     2100

aagcuaaaca agcauauguu gacaaguugg aagaauuaau gaaaauuggc acuccaguua     2160

aaguucgguu ucaggaagcu gaagaacggc caaaaauguu ugaagaacua ggacagaggc     2220

ugcagcauua ugccaagaua gcagcugacu ucagaaauaa ggaugagaaa uacaaccaua     2280

uugaugaguc ugaaaugaaa aaaguggaga agucuguuaa ugaagugaug gaauggauga     2340

auaaugucau gaaugcucag gcuaaaaaga gucuugauca ggauccaguu guacgugcuc     2400

aggaaauuaa aacaaaaauc aaggaauuga acaacacaug ugaacccguu guaacacaac     2460

cgaaaccaaa aauugaauca cccaaacugg aaagaacucc aaauggccca aauauugaua     2520

aaaaggaaga agauuuagaa gacaaaaaca auuuuggugc ugaaccucca caucagaaug     2580

gugaauguua cccuaaugag aaaaauucug uuaauaugga cuuggacuag ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  2661
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (wt)

<400>  2661
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

acaaaguuag gaggcagagg ccgaggaggc gagucuguug ggccuuggug gcugugcucu      120

uggcagaccu guuggcacug agugauacac uggcagugau gucuguggac cugggcagug      180

aguccaugaa gguggccauu gucaaaccug gagugcccau ggaaauuguc uugaauaagg      240

aaucucggag gaaaacaccg gugaucguga cccugaaaga aaaugaaaga uucuuuggag      300

acagugcagc aagcauggcg auuaagaauc caaaggcuac gcuacguuac uuccagcacc      360

uccuggggaa gcaggcagau aacccccaug uagcucuuua ccaggcccgc uucccggagc      420

acgagcugac uuucgaccca cagaggcaga cugugcacuu ucagaucagc ucgcagcugc      480

aguucucacc ugaggaagug uugggcaugg uucucaauua uucucguucu cuagcugaag      540

auuuugcaga gcagcccauc aaggaugcag ugaucaccgu gccagucuuc uucaaccagg      600

ccgagcgccg agcugugcug caggcugcuc guauggcugg ccucaaagug cugcagcuca      660

ucaaugacaa caccgccacu gcccucagcu auggugucuu ccgccggaaa gauauuaaca      720

ccacugccca gaauaucaug uucuaugaca ugggcucagg cagcaccgua ugcaccauug      780

ugaccuacca gauggugaag acuaaggaag cugggaugca gccacagcug cagauccggg      840

gaguaggauu ugaccguacc cuggggggcc uggagaugga gcuccggcuu cgagaacgcc      900

uggcugggcu uuucaaugag cagcgcaagg gucagagagc aaaggaugug cgggagaacc      960

cgcgugccau ggccaagcug cugcgugagg cuaaucggcu caaaaccguc cucagugcca     1020

acgcugacca cauggcacag auugaaggcc ugauggauga uguggacuuc aaggcaaaag     1080

ugacucgugu ggaauuugag gaguugugug cagacuuguu ugagcgggug ccugggccug     1140

uacagcaggc ccuccagagu gccgaaauga gucuggauga gauugagcag gugauccugg     1200

uggguggggc cacucggguc cccagaguuc aggaggugcu gcugaaggcc gugggcaagg     1260

aggagcuggg gaagaacauc aaugcagaug aagcagccgc caugggggca guguaccagg     1320

cagcugcgcu cagcaaagcc uuuaaaguga agccauuugu cguccgagau gcaguggucu     1380

accccauccu gguggaguuc acgagggagg uggaggagga gccugggauu cacagccuga     1440

agcacaauaa acggguacuc uucucucgga uggggcccua cccucaacgc aaagucauca     1500

ccuuuaaccg cuacagccau gauuucaacu uccacaucaa cuacggcgac cugggcuucc     1560

uggggccuga agaucuucgg guauuuggcu cccagaaucu gaccacagug aagcuaaaag     1620

ggguggguga cagcuucaag aaguauccug acuacgaguc caagggcauc aaggcucacu     1680

ucaaccugga ugagaguggc gugcucaguc uagacagggu ggagucugua uuugagacac     1740

ugguagagga cagcgcagaa gaggaaucua cucucaccaa acuuggcaac accauuucca     1800

gccuguuugg aggcgguacc acaccagaug ccaaggagaa ugguacugau acuguccagg     1860

aggaagagga gagcccugca gaggggagca aggacgagcc uggggagcag guggagcuca     1920

aggaggaagc ugaggcccca guggaggaug gcucucagcc cccacccccu gaaccuaagg     1980

gagaugcaac cccugaggga gaaaaggcca cagaaaaaga aaauggggac aagucugagg     2040

cccagaaacc aagugagaag gcagaggcag ggccugaggg cgucgcucca gccccagagg     2100

gagagaagaa gcagaagccc gccaggaagc ggcgaauggu agaggagauc gggguggagc     2160

ugguuguucu ggaccugccu gacuugccag aggauaagcu ggcucagucg gugcagaaac     2220

uucaggacuu gacacuccga gaccuggaga agcaggaacg ggaaaaagcu gccaacagcu     2280

uggaagcauu cauauuugag acccaggaca agcuguacca gcccgaguac caggaagugu     2340

ccacagagga gcagcgugag gagaucucug ggaagcucag cgccgcaucc accuggcugg     2400

aggaugaggg uguuggagcc accacaguga uguugaagga gaagcuggcu gagcugagga     2460

agcugugcca agggcuguuu uuucggguag aggagcgcaa gaaguggccc gaacggcugu     2520

cugcccucga uaaucuccuc aaccauucca gcauguuccu caagggggcc cggcucaucc     2580

cagagaugga ccagaucuuc acugaggugg agaugacaac guuagagaaa gucaucaaug     2640

agaccugggc cuggaagaau gcaacucugg ccgagcaggc uaagcugccc gccacagaga     2700

agccuguguu gcucucaaaa gacauugaag cuaagaugau ggcccuggac cgagaggugc     2760

aguaucugcu caauaaggcc aaguuuacca agccccggcc ccggccuaag gacaagaaug     2820

ggacccgggc agagccaccc cucaaugcca gugccaguga ccagggggag aaggucaucc     2880

cuccagcagg ccagacugaa gaugcagagc ccauuucaga accugagaaa guagagacug     2940

gauccgagcc aggagacacu gagccuuugg aguuaggagg uccuggagca gaaccugaac     3000

agaaagaaca aucgacagga cagaagcggc cuuugaagaa cgacgaacua uaaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  2662
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (wt)

<400>  2662
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccug       60

aggaaaccca gacccaagac caaccgaugg aggaggagga gguugagacg uucgccuuuc      120

aggcagaaau ugcccaguug augucauuga ucaucaauac uuucuacucg aacaaagaga      180

ucuuucugag agagcucauu ucaaauucau cagaugcauu ggacaaaauc cgguaugaaa      240

gcuugacaga ucccaguaaa uuagacucug ggaaagagcu gcauauuaac cuuauaccga      300

acaaacaaga ucgaacucuc acuauugugg auacuggaau uggaaugacc aaggcugacu      360

ugaucaauaa ccuugguacu aucgccaagu cugggaccaa agcguucaug gaagcuuugc      420

aggcuggugc agauaucucu augauuggcc aguucggugu ugguuuuuau ucugcuuauu      480

ugguugcuga gaaaguaacu gugaucacca aacauaacga ugaugagcag uacgcuuggg      540

aguccucagc agggggauca uucacaguga ggacagacac aggugaaccu augggucgug      600

gaacaaaagu uauccuacac cugaaagaag accaaacuga guacuuggag gaacgaagaa      660

uaaaggagau ugugaagaaa cauucucagu uuauuggaua ucccauuacu cuuuuugugg      720

agaaggaacg ugauaaagaa guaagcgaug augaggcuga agaaaaggaa gacaaagaag      780

aagaaaaaga aaaagaagag aaagagucgg aagacaaacc ugaaauugaa gauguugguu      840

cugaugagga agaagaaaag aaggauggug acaagaagaa gaagaagaag auuaaggaaa      900

aguacaucga ucaagaagag cucaacaaaa caaagcccau cuggaccaga aaucccgacg      960

auauuacuaa ugaggaguac ggagaauucu auaagagcuu gaccaaugac ugggaagauc     1020

acuuggcagu gaagcauuuu ucaguugaag gacaguugga auucagagcc cuucuauuug     1080

ucccacgacg ugcuccuuuu gaucuguuug aaaacagaaa gaaaaagaac aacaucaaau     1140

uguauguacg cagaguuuuc aucauggaua acugugagga gcuaaucccu gaauaucuga     1200

acuucauuag agggguggua gacucggagg aucucccucu aaacauaucc cgugagaugu     1260

ugcaacaaag caaaauuuug aaaguuauca ggaagaauuu ggucaaaaaa ugcuuagaac     1320

ucuuuacuga acuggcggaa gauaaagaga acuacaagaa auucuaugag caguucucua     1380

aaaacauaaa gcuuggaaua cacgaagacu cucaaaaucg gaagaagcuu ucagagcugu     1440

uaagguacua cacaucugcc ucuggugaug agaugguuuc ucucaaggac uacugcacca     1500

gaaugaagga gaaccagaaa cauaucuauu auaucacagg ugagaccaag gaccagguag     1560

cuaacucagc cuuuguggaa cgucuucgga aacauggcuu agaagugauc uauaugauug     1620

agcccauuga ugaguacugu guccaacagc ugaaggaauu ugaggggaag acuuuagugu     1680

cagucaccaa agaaggccug gaacuuccag aggaugaaga agagaaaaag aagcaggaag     1740

agaaaaaaac aaaguuugag aaccucugca aaaucaugaa agacauauug gagaaaaaag     1800

uugaaaaggu gguuguguca aaccgauugg ugacaucucc augcuguauu gucacaagca     1860

cauauggcug gacagcaaac auggagagaa ucaugaaagc ucaagcccua agagacaacu     1920

caacaauggg uuacauggca gcaaagaaac accuggagau aaacccugac cauuccauua     1980

uugagaccuu aaggcaaaag gcagaggcug auaagaacga caagucugug aaggaucugg     2040

ucaucuugcu uuaugaaacu gcgcuccugu cuucuggcuu cagucuggaa gauccccaga     2100

cacaugcuaa caggaucuac aggaugauca aacuuggucu ggguauugau gaagaugacc     2160

cuacugcuga ugauaccagu gcugcuguaa cugaagaaau gccaccccuu gaaggagaug     2220

acgacacauc acgcauggaa gaaguagacu aaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  2663
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (wt)

<400>  2663
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggauu       60

ccaguaaauu agacucuggg aaagggcugc auauuaaccu uguaccaaac aaacaaaauc      120

aaacccucac uauuguggac acuagaauug gaaugaccaa gacugacuug aucaauaacc      180

ucgguacugu caccaagucu gggaccaaag cauucaugga agcuuugcag gcugaugcag      240

auaucucuau gauuggccau uucgggguug guuuuuauuc ugcuuauuug guugccaaga      300

aaguaacugu gaucagcaaa cauaacaaug augagcagua caccugggag uccucagcag      360

ggggaucauu cacagugagg acagacgagu gaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  2664
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (wt)

<400>  2664
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccug       60

aggaagugca ccauggagag gaggaggugg agacuuuugc cuuucaggca gaaauugccc      120

aacucauguc ccucaucauc aauaccuucu auuccaacaa ggagauuuuc cuucgggagu      180

ugaucucuaa ugcuucugau gccuuggaca agauucgcua ugagagccug acagacccuu      240

cgaaguugga cagugguaaa gagcugaaaa uugacaucau ccccaacccu caggaacgua      300

cccugacuuu gguagacaca ggcauuggca ugaccaaagc ugaucucaua aauaauuugg      360

gaaccauugc caagucuggu acuaaagcau ucauggaggc ucuucaggcu ggugcagaca      420

ucuccaugau ugggcaguuu gguguuggcu uuuauucugc cuacuuggug gcagagaaag      480

ugguugugau cacaaagcac aacgaugaug aacaguaugc uugggagucu ucugcuggag      540

guuccuucac ugugcgugcu gaccauggug agcccauugg cagggguacc aaagugaucc      600

uccaucuuaa agaagaucag acagaguacc uagaagagag gcgggucaaa gaaguaguga      660

agaagcauuc ucaguucaua ggcuauccca ucacccuuua uuuggagaag gaacgagaga      720

aggaaauuag ugaugaugag gcagaggaag agaaagguga gaaagaagag gaagauaaag      780

augaugaaga aaaacccaag aucgaagaug uggguucaga ugaggaggau gacagcggua      840

aggauaagaa gaagaaaacu aagaagauca aagagaaaua cauugaucag gaagaacuaa      900

acaagaccaa gccuauuugg accagaaacc cugaugacau cacccaagag gaguauggag      960

aauucuacaa gagccucacu aaugacuggg aagaccacuu ggcagucaag cacuuuucug     1020

uagaagguca guuggaauuc agggcauugc uauuuauucc ucgucgggcu cccuuugacc     1080

uuuuugagaa caagaagaaa aagaacaaca ucaaacucua uguccgccgu guguucauca     1140

uggacagcug ugaugaguug auaccagagu aucucaauuu uauccguggu gugguugacu     1200

cugaggaucu gccccugaac aucucccgag aaaugcucca gcagagcaaa aucuugaaag     1260

ucauucgcaa aaacauuguu aagaagugcc uugagcucuu cucugagcug gcagaagaca     1320

aggagaauua caagaaauuc uaugaggcau ucucuaaaaa ucucaagcuu ggaauccacg     1380

aagacuccac uaaccgccgc cgccugucug agcugcugcg cuaucauacc ucccagucug     1440

gagaugagau gacaucucug ucagaguaug uuucucgcau gaaggagaca cagaagucca     1500

ucuauuacau cacuggugag agcaaagagc agguggccaa cucagcuuuu guggagcgag     1560

ugcggaaacg gggcuucgag gugguauaua ugaccgagcc cauugacgag uacugugugc     1620

agcagcucaa ggaauuugau gggaagagcc uggucucagu uaccaaggag ggucuggagc     1680

ugccugagga ugaggaggag aagaagaaga uggaagagag caaggcaaag uuugagaacc     1740

ucugcaagcu caugaaagaa aucuuagaua agaagguuga gaaggugaca aucuccaaua     1800

gacuuguguc uucaccuugc ugcauuguga ccagcaccua cggcuggaca gccaauaugg     1860

agcggaucau gaaagcccag gcacuucggg acaacuccac caugggcuau augauggcca     1920

aaaagcaccu ggagaucaac ccugaccacc ccauugugga gacgcugcgg cagaaggcug     1980

aggccgacaa gaaugauaag gcaguuaagg accugguggu gcugcuguuu gaaaccgccc     2040

ugcuaucuuc uggcuuuucc cuugaggauc cccagaccca cuccaaccgc aucuaucgca     2100

ugaucaagcu aggucuaggu auugaugaag augaaguggc agcagaggaa cccaaugcug     2160

caguuccuga ugagaucccc ccucucgagg gcgaugagga ugcgucucgc auggaagaag     2220

ucgauuaggg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  2665
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (wt)

<400>  2665
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaggg       60

cccugugggu gcugggccuc ugcugcgucc ugcugaccuu cgggucgguc agagcugacg      120

augaaguuga uguggauggu acaguagaag aggaucuggg uaaaaguaga gaaggaucaa      180

ggacggauga ugaaguagua cagagagagg aagaagcuau ucaguuggau ggauuaaaug      240

caucacaaau aagagaacuu agagagaagu cggaaaaguu ugccuuccaa gccgaaguua      300

acagaaugau gaaacuuauc aucaauucau uguauaaaaa uaaagagauu uuccugagag      360

aacugauuuc aaaugcuucu gaugcuuuag auaagauaag gcuaauauca cugacugaug      420

aaaaugcucu uucuggaaau gaggaacuaa cagucaaaau uaagugugau aaggagaaga      480

accugcugca ugucacagac accgguguag gaaugaccag agaagaguug guuaaaaacc      540

uugguaccau agccaaaucu gggacaagcg aguuuuuaaa caaaaugacu gaagcacagg      600

aagauggcca gucaacuucu gaauugauug gccaguuugg ugucgguuuc uauuccgccu      660

uccuuguagc agauaagguu auugucacuu caaaacacaa caacgauacc cagcacaucu      720

gggagucuga cuccaaugaa uuuucuguaa uugcugaccc aagaggaaac acucuaggac      780

ggggaacgac aauuacccuu gucuuaaaag aagaagcauc ugauuaccuu gaauuggaua      840

caauuaaaaa ucucgucaaa aaauauucac aguucauaaa cuuuccuauu uauguaugga      900

gcagcaagac ugaaacuguu gaggagccca uggaggaaga agaagcagcc aaagaagaga      960

aagaagaauc ugaugaugaa gcugcaguag aggaagaaga agaagaaaag aaaccaaaga     1020

cuaaaaaagu ugaaaaaacu gucugggacu gggaacuuau gaaugauauc aaaccaauau     1080

ggcagagacc aucaaaagaa guagaagaag augaauacaa agcuuucuac aaaucauuuu     1140

caaaggaaag ugaugacccc auggcuuaua uucacuuuac ugcugaaggg gaaguuaccu     1200

ucaaaucaau uuuauuugua cccacaucug cuccacgugg ucuguuugac gaauauggau     1260

cuaaaaagag cgauuacauu aagcucuaug ugcgccgugu auucaucaca gacgacuucc     1320

augauaugau gccuaaauac cucaauuuug ucaagggugu gguggacuca gaugaucucc     1380

ccuugaaugu uucccgcgag acucuucagc aacauaaacu gcuuaaggug auuaggaaga     1440

agcuuguucg uaaaacgcug gacaugauca agaagauugc ugaugauaaa uacaaugaua     1500

cuuuuuggaa agaauuuggu accaacauca agcuuggugu gauugaagac cacucgaauc     1560

gaacacgucu ugcuaaacuu cuuagguucc agucuucuca ucauccaacu gacauuacua     1620

gccuagacca guauguggaa agaaugaagg aaaaacaaga caaaaucuac uucauggcug     1680

gguccagcag aaaagaggcu gaaucuucuc cauuuguuga gcgacuucug aaaaagggcu     1740

augaaguuau uuaccucaca gaaccugugg augaauacug uauucaggcc cuucccgaau     1800

uugaugggaa gagguuccag aauguugcca aggaaggagu gaaguucgau gaaagugaga     1860

aaacuaagga gagucgugaa gcaguugaga aagaauuuga gccucugcug aauuggauga     1920

aagauaaagc ccuuaaggac aagauugaaa aggcuguggu gucucagcgc cugacagaau     1980

cuccgugugc uuugguggcc agccaguacg gauggucugg caacauggag agaaucauga     2040

aagcacaagc guaccaaacg ggcaaggaca ucucuacaaa uuacuaugcg agucagaaga     2100

aaacauuuga aauuaauccc agacacccgc ugaucagaga caugcuucga cgaauuaagg     2160

aagaugaaga ugauaaaaca guuuuggauc uugcuguggu uuuguuugaa acagcaacgc     2220

uucggucagg guaucuuuua ccagacacua aagcauaugg agauagaaua gaaagaaugc     2280

uucgccucag uuugaacauu gacccugaug caaaggugga agaagagccc gaagaagaac     2340

cugaagagac agcagaagac acaacagaag acacagagca agacgaagau gaagaaaugg     2400

augugggaac agaugaagaa gaagaaacag caaaggaauc uacagcugaa aaagaugaau     2460

uguaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  2666
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (wt)

<400>  2666
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcgc       60

gcgagcugcg ggcgcugcug cuguggggcc gccgccugcg gccuuugcug cgggcgccgg      120

cgcuggcggc cgugccggga ggaaaaccaa uucugugucc ucggaggacc acagcccagu      180

ugggccccag gcgaaaccca gccuggagcu ugcaggcagg acgacuguuc agcacgcaga      240

ccgccgagga caaggaggaa ccccugcacu cgauuaucag cagcacagag agcgugcagg      300

guuccacuuc caaacaugag uuccaggccg agacaaagaa gcuuuuggac auuguugccc      360

ggucccugua cucagaaaaa gagguguuua uacgggagcu gaucuccaau gccagcgaug      420

ccuuggaaaa acugcgucac aaacuggugu cugacggcca agcacugcca gaaauggaga      480

uucacuugca gaccaaugcc gagaaaggca ccaucaccau ccaggauacu gguaucggga      540

ugacacagga agagcuggug uccaaccugg ggacgauugc cagaucgggg ucaaaggccu      600

uccuggaugc ucugcagaac caggcugagg ccagcagcaa gaucaucggc caguuuggag      660

uggguuucua cucagcuuuc augguggcug acagagugga ggucuauucc cgcucggcag      720

ccccggggag ccuggguuac caguggcuuu cagaugguuc uggaguguuu gaaaucgccg      780

aagcuucggg aguuagaacc gggacaaaaa ucaucaucca ccugaaaucc gacugcaagg      840

aguuuuccag cgaggcccgg gugcgagaug ugguaacgaa guacagcaac uucgucagcu      900

uccccuugua cuugaaugga aggcggauga acaccuugca ggccaucugg augauggacc      960

ccaaggaugu ccgugagugg caacaugagg aguucuaccg cuacgucgcg caggcucacg     1020

acaagccccg cuacacccug cacuauaaga cggacgcacc gcucaacauc cgcagcaucu     1080

ucuacgugcc cgacaugaaa ccguccaugu uugaugugag ccgggagcug ggcuccagcg     1140

uugcacugua cagccgcaaa guccucaucc agaccaaggc cacggacauc cugcccaagu     1200

ggcugcgcuu cauccgaggu gugguggaca gugaggacau uccccugaac cucagccggg     1260

agcugcugca ggagagcgca cucaucagga aacuccggga cguuuuacag cagaggcuga     1320

ucaaauucuu cauugaccag aguaaaaaag augcugagaa guaugcaaag uuuuuugaag     1380

auuacggccu guucaugcgg gagggcauug ugaccgccac cgagcaggag gucaaggagg     1440

acauagcaaa gcugcugcgc uacgaguccu cggcgcugcc cuccgggcag cuaaccagcc     1500

ucucagaaua cgccagccgc augcgggccg gcacccgcaa caucuacuac cugugcgccc     1560

ccaaccguca ccuggcagag cacucacccu acuaugaggc caugaagaag aaagacacag     1620

agguucucuu cugcuuugag caguuugaug agcucacccu gcugcaccuu cgugaguuug     1680

acaagaagaa gcugaucucu guggagacgg acauagucgu ggaucacuac aaggaggaga     1740

aguuugagga caggucccca gccgccgagu gccuaucaga gaaggagacg gaggagcuca     1800

uggccuggau gagaaaugug cuggggucgc gugucaccaa cgugaaggug acccuccgac     1860

uggacaccca cccugccaug gucaccgugc uggagauggg ggcugcccgc cacuuccugc     1920

gcaugcagca gcuggccaag acccaggagg agcgcgcaca gcuccugcag cccacgcugg     1980

agaucaaccc caggcacgcg cucaucaaga agcugaauca gcugcgcgca agcgagccug     2040

gccuggcuca gcugcuggug gaucagauau acgagaacgc caugauugcu gcuggacuug     2100

uugacgaccc uagggccaug gugggccgcu ugaaugagcu gcuugucaag gcccuggagc     2160

gacacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  2667
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (wt)

<400>  2667
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

aaaucagcag ucuuccaacc caauuauuua agugcugcuu uugugauuuc uugaagguga      120

agaugcacac cauguccucc ucgcaucucu ucuaccuggc gcugugccug cucaccuuca      180

ccagcucugc cacggcugga ccggagacgc ucugcggggc ugagcuggug gaugcucuuc      240

aguucgugug uggagacagg ggcuuuuauu ucaacaagcc cacaggguau ggcuccagca      300

gucggagggc gccucagaca ggcaucgugg augagugcug cuuccggagc ugugaucuaa      360

ggaggcugga gauguauugc gcaccccuca agccugccaa gucagcucgc ucuguccgug      420

cccagcgcca caccgacaug cccaagaccc agaaggaagu acauuugaag aacgcaagua      480

gagggagugc aggaaacaag aacuacagga uguagggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  2668
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (wt)

<400>  2668
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

ucccaauggg gaagucgaug cuggugcuuc ucaccuucuu ggccuucgcc ucgugcugca      120

uugcugcuua ccgccccagu gagacccugu gcggcgggga gcugguggac acccuccagu      180

ucgucugugg ggaccgcggc uucuacuuca gcaggcccgc aagccgugug agccgucgca      240

gccguggcau cguugaggag ugcuguuucc gcagcuguga ccuggcccuc cuggagacgu      300

acugugcuac ccccgccaag uccgagaggg acgugucgac cccuccgacc gugcuuccgg      360

acaacuuccc cagauacccc gugggcaagu ucuuccaaua ugacaccugg aagcagucca      420

cccagcgccu gcgcaggggc cugccugccc uccugcgugc ccgccggggu cacgugcucg      480

ccaaggagcu cgaggcguuc agggaggcca aacgucaccg uccccugauu gcucuaccca      540

cccaagaccc cgcccacggg ggcgcccccc cagagauggc cagcaaucgg aagugaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  2669
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (wt)

<400>  2669
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

ccuucuccac aagcgccuuc gguccaguug ccuucucccu ggggcugcuc cugguguugc      120

cugcugccuu cccugcccca guacccccag gagaagauuc caaagaugua gccgccccac      180

acagacagcc acucaccucu ucagaacgaa uugacaaaca aauucgguac auccucgacg      240

gcaucucagc ccugagaaag gagacaugua acaagaguaa caugugugaa agcagcaaag      300

aggcacuggc agaaaacaac cugaaccuuc caaagauggc ugaaaaagau ggaugcuucc      360

aaucuggauu caaugaggag acuugccugg ugaaaaucau cacuggucuu uuggaguuug      420

agguauaccu agaguaccuc cagaacagau uugagaguag ugaggaacaa gccagagcug      480

ugcagaugag uacaaaaguc cugauccagu uccugcagaa aaaggcaaag aaucuagaug      540

caauaaccac cccugaccca accacaaaug ccagccugcu gacgaagcug caggcacaga      600

accaguggcu gcaggacaug acaacucauc ucauucugcg cagcuuuaag gaguuccugc      660

aguccagccu gagggcucuu cggcaaaugu agggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  2670
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (wt)

<400>  2670
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccu       60

ugcuuuggcu gagaggauuu cuguuggcaa guugcuggau uauagugagg aguuccccca      120

ccccaggauc cgaggggcac agcgcggccc ccgacugucc guccugugcg cuggccgccc      180

ucccaaagga uguacccaac ucucagccag agauggugga ggccgucaag aagcacauuu      240

uaaacaugcu gcacuugaag aagagacccg augucaccca gccgguaccc aaggcggcgc      300

uucugaacgc gaucagaaag cuucaugugg gcaaagucgg ggagaacggg uauguggaga      360

uagaggauga cauuggaagg agggcagaaa ugaaugaacu uauggagcag accucggaga      420

ucaucacguu ugccgaguca ggaacagcca ggaagacgcu gcacuucgag auuuccaagg      480

aaggcaguga ccugucagug guggagcgug cagaagucug gcucuuccua aaagucccca      540

aggccaacag gaccaggacc aaagucacca uccgccucuu ccagcagcag aagcacccgc      600

agggcagcuu ggacacaggg gaagaggccg aggaaguggg cuuaaagggg gagaggagug      660

aacuguugcu cucugaaaaa guaguagacg cucggaagag caccuggcau gucuucccug      720

ucuccagcag cauccagcgg uugcuggacc agggcaagag cucccuggac guucggauug      780

ccugugagca gugccaggag aguggcgcca gcuugguucu ccugggcaag aagaagaaga      840

aagaagagga gggggaaggg aaaaagaagg gcggagguga agguggggca ggagcagaug      900

aggaaaagga gcagucgcac agaccuuucc ucaugcugca ggcccggcag ucugaagacc      960

acccucaucg ccggcgucgg cggggcuugg agugugaugg caaggucaac aucugcugua     1020

agaaacaguu cuuugucagu uucaaggaca ucggcuggaa ugacuggauc auugcucccu     1080

cuggcuauca ugccaacuac ugcgagggug agugcccgag ccauauagca ggcacguccg     1140

gguccucacu guccuuccac ucaacaguca ucaaccacua ccgcaugcgg ggccauagcc     1200

ccuuugccaa ccucaaaucg ugcugugugc ccaccaagcu gagacccaug uccauguugu     1260

acuaugauga uggucaaaac aucaucaaaa aggacauuca gaacaugauc guggaggagu     1320

gugggugcuc auagggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  2671
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (wt)

<400>  2671
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacg       60

ggcugcccgg ucgggcgcug ggggccgccu gccuucugcu gcuggcggcc ggcuggcugg      120

ggccugaggc cuggggcuca cccacgcccc cgccgacgcc ugccgcgccg ccgccacccc      180

cgccacccgg auccccgggu ggcucgcagg acaccuguac gucgugcggc ggcuuccggc      240

ggccagagga gcucggccga guggacggcg acuuccugga ggcggugaag cggcacaucu      300

ugagccgccu gcagaugcgg ggccggccca acaucacgca cgccgugccu aaggccgcca      360

uggucacggc ccugcgcaag cugcacgcgg gcaaggugcg cgaggacggc cgcguggaga      420

ucccgcaccu cgacggccac gccagcccgg gcgccgacgg ccaggagcgc guuuccgaaa      480

ucaucagcuu cgccgagaca gauggccucg ccuccucccg gguccgccua uacuucuuca      540

ucuccaacga aggcaaccag aaccuguuug ugguccaggc cagccugugg cuuuaccuga      600

aacuccugcc cuacguccug gagaagggca gccggcggaa ggugcggguc aaaguguacu      660

uccaggagca gggccacggu gacaggugga acauggugga gaagagggug gaccucaagc      720

gcagcggcug gcauaccuuc ccacucacgg aggccaucca ggccuuguuu gagcggggcg      780

agcggcgacu caaccuagac gugcagugug acagcugcca ggagcuggcc guggugccgg      840

uguucgugga cccaggcgaa gagucgcacc ggcccuuugu gguggugcag gcucggcugg      900

gcgacagcag gcaccgcauu cgcaagcgag gccuggagug cgauggccgg accaaccucu      960

guugcaggca acaguucuuc auugacuucc gccucaucgg cuggaacgac uggaucauag     1020

cacccaccgg cuacuacggg aacuacugug agggcagcug cccagccuac cuggcagggg     1080

uccccggcuc ugccuccucc uuccacacgg cuguggugaa ccaguaccgc augcgggguc     1140

ugaaccccgg cacggugaac uccugcugca uucccaccaa gcugagcacc auguccaugc     1200

uguacuucga ugaugaguac aacaucguca agcgggacgu gcccaacaug auuguggagg     1260

agugcggcug cgccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  2672
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (wt)

<400>  2672
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcuc       60

ucagaguccu ucuguuaaca gccuugaccu uaugucaugg guucaacuug gacacugaaa      120

acgcaaugac cuuccaagag aacgcaaggg gcuucgggca gagcgugguc cagcuucagg      180

gauccagggu ggugguugga gccccccagg agauaguggc ugccaaccaa aggggcagcc      240

ucuaccagug cgacuacagc acaggcucau gcgagcccau ccgccugcag guccccgugg      300

aggccgugaa caugucccug ggccuguccc uggcagccac caccagcccc ccucagcugc      360

uggccugugg ucccaccgug caccagacuu gcagugagaa cacguaugug aaagggcucu      420

gcuuccuguu uggauccaac cuacggcagc agccccagaa guucccagag gcccuccgag      480

gguguccuca agaggauagu gacauugccu ucuugauuga uggcucuggu agcaucaucc      540

cacaugacuu ucggcggaug aaggaguuug ucucaacugu gauggagcaa uuaaaaaagu      600

ccaaaaccuu guucucuuug augcaguacu cugaagaauu ccggauucac uuuaccuuca      660

aagaguucca gaacaacccu aacccaagau cacuggugaa gccaauaacg cagcugcuug      720

ggcggacaca cacggccacg ggcauccgca aagugguacg agagcuguuu aacaucacca      780

acggagcccg aaagaaugcc uuuaagaucc uaguugucau cacggaugga gaaaaguuug      840

gcgaucccuu gggauaugag gaugucaucc cugaggcaga cagagaggga gucauucgcu      900

acgucauugg ggugggagau gccuuccgca gugagaaauc ccgccaagag cuuaauacca      960

ucgcauccaa gccgccucgu gaucacgugu uccaggugaa uaacuuugag gcucugaaga     1020

ccauucagaa ccagcuucgg gagaagaucu uugcgaucga ggguacucag acaggaagua     1080

gcagcuccuu ugagcaugag augucucagg aaggcuucag cgcugccauc accucuaaug     1140

gccccuugcu gagcacugug gggagcuaug acugggcugg uggagucuuu cuauauacau     1200

caaaggagaa aagcaccuuc aucaacauga ccagagugga uucagacaug aaugaugcuu     1260

acuuggguua ugcugccgcc aucaucuuac ggaaccgggu gcaaagccug guucuggggg     1320

caccucgaua ucagcacauc ggccugguag cgauguucag gcagaacacu ggcauguggg     1380

aguccaacgc uaaugucaag ggcacccaga ucggcgccua cuucggggcc ucccucugcu     1440

ccguggacgu ggacagcaac ggcagcaccg accugguccu caucggggcc ccccauuacu     1500

acgagcagac ccgagggggc cagguguccg ugugccccuu gcccaggggg agggcucggu     1560

ggcaguguga ugcuguucuc uacggggagc agggccaacc cuggggccgc uuuggggcag     1620

cccuaacagu gcugggggac guaaaugggg acaagcugac ggacguggcc auuggggccc     1680

caggagagga ggacaaccgg ggugcuguuu accuguuuca cggaaccuca ggaucuggca     1740

ucagccccuc ccauagccag cggauagcag gcuccaagcu cucucccagg cuccaguauu     1800

uuggucaguc acugaguggg ggccaggacc ucacaaugga uggacuggua gaccugacug     1860

uaggagccca ggggcacgug cugcugcuca ggucccagcc aguacugaga gucaaggcaa     1920

ucauggaguu caaucccagg gaaguggcaa ggaauguauu ugaguguaau gaucaggugg     1980

ugaaaggcaa ggaagccgga gaggucagag ucugccucca uguccagaag agcacacggg     2040

aucggcuaag agaaggacag auccagagug uugugacuua ugaccuggcu cuggacuccg     2100

gccgcccaca uucccgcgcc gucuucaaug agacaaagaa cagcacacgc agacagacac     2160

aggucuuggg gcugacccag acuugugaga cccugaaacu acaguugccg aauugcaucg     2220

aggacccagu gagccccauu gugcugcgcc ugaacuucuc ucugguggga acgccauugu     2280

cugcuuucgg gaaccuccgg ccagugcugg cggaggaugc ucagagacuc uucacagccu     2340

uguuucccuu ugagaagaau uguggcaaug acaacaucug ccaggaugac cucagcauca     2400

ccuucaguuu caugagccug gacugccucg uggugggugg gccccgggag uucaacguga     2460

cagugacugu gagaaaugau ggugaggacu ccuacaggac acaggucacc uucuucuucc     2520

cgcuugaccu guccuaccgg aaggugucca cgcuccagaa ccagcgcuca cagcgauccu     2580

ggcgccuggc cugugagucu gccuccucca ccgaaguguc uggggccuug aagagcacca     2640

gcugcagcau aaaccacccc aucuucccgg aaaacucaga ggucaccuuu aauaucacgu     2700

uugauguaga cucuaaggcu ucccuuggaa acaaacugcu ccucaaggcc aaugugacca     2760

gugagaacaa caugcccaga accaacaaaa ccgaauucca acuggagcug ccggugaaau     2820

augcugucua cauggugguc accagccaug gggucuccac uaaauaucuc aacuucacgg     2880

ccucagagaa uaccagucgg gucaugcagc aucaauauca ggucagcaac cuggggcaga     2940

ggagccuccc caucagccug guguucuugg ugcccguccg gcugaaccag acugucauau     3000

gggaccgccc ccaggucacc uucuccgaga accucucgag uacgugccac accaaggagc     3060

gcuugcccuc ucacuccgac uuucuggcug agcuucggaa ggcccccgug gugaacugcu     3120

ccaucgcugu cugccagaga auccagugug acaucccguu cuuuggcauc caggaagaau     3180

ucaaugcuac ccucaaaggc aaccucucgu uugacuggua caucaagacc ucgcauaacc     3240

accuccugau cgugagcaca gcugagaucu uguuuaacga uuccguguuc acccugcugc     3300

cgggacaggg ggcguuugug aggucccaga cggagaccaa aguggagccg uucgaggucc     3360

ccaacccccu gccgcucauc gugggcagcu cugucggggg acugcugcuc cuggcccuca     3420

ucaccgccgc gcuguacaag cucggcuucu ucaagcggca auacaaggac augaugagug     3480

aagggggucc cccgggggcc gaaccccagu agggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  2673
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (wt)

<400>  2673
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguucu       60

cccugaagac gcuuccauuu cugcucuuac uccaugugca gauuuccaag gccuuuccug      120

uaucuucuaa agagaaaaau acaaaaacug uucaggacua ccuggaaaag uucuaccaau      180

uaccaagcaa ccaguaucag ucuacaagga agaauggcac uaaugugauc guugaaaagc      240

uuaaagaaau gcagcgauuu uuuggguuga augugacggg gaagccaaau gaggaaacuc      300

uggacaugau gaaaaagccu cgcuguggag ugccugacag uggugguuuu auguuaaccc      360

caggaaaccc caagugggaa cgcacuaacu ugaccuacag gauucgaaac uauaccccac      420

agcugucaga ggcugaggua gaaagagcua ucaaggaugc cuuugaacuc uggaguguug      480

caucaccucu caucuucacc aggaucucac agggagaggc agauaucaac auugcuuuuu      540

accaaagaga ucacggugac aauucuccau uugauggacc caauggaauc cuugcucaug      600

ccuuucagcc aggccaaggu auuggaggag augcucauuu ugaugccgaa gaaacaugga      660

ccaacaccuc cgcaaauuac aacuuguuuc uuguugcugc ucaugaauuu ggccauucuu      720

uggggcucgc ucacuccucu gacccuggug ccuugaugua ucccaacuau gcuuucaggg      780

aaaccagcaa cuacucacuc ccucaagaug acaucgaugg cauucaggcc aucuauggac      840

uuucaagcaa cccuauccaa ccuacuggac caagcacacc caaacccugu gaccccaguu      900

ugacauuuga ugcuaucacc acacuccgug gagaaauacu uuucuuuaaa gacagguacu      960

ucuggagaag gcauccucag cuacaaagag ucgaaaugaa uuuuauuucu cuauucuggc     1020

caucccuucc aacugguaua caggcugcuu augaagauuu ugacagagac cucauuuucc     1080

uauuuaaagg caaccaauac ugggcucuga guggcuauga uauucugcaa gguuauccca     1140

aggauauauc aaacuauggc uuccccagca gcguccaagc aauugacgca gcuguuuucu     1200

acagaaguaa aacauacuuc uuuguaaaug accaauucug gagauaugau aaccaaagac     1260

aauucaugga gccagguuau cccaaaagca uaucaggugc cuuuccagga auagagagua     1320

aaguugaugc aguuuuccag caagaacauu ucuuccaugu cuucagugga ccaagauauu     1380

acgcauuuga ucuuauugcu cagagaguua ccagaguugc aagaggcaau aaauggcuua     1440

acuguagaua uggcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  2674
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (wt)

<400>  2674
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

ucuggcagcc ccugguccug gugcuccugg ugcugggcug cugcuuugcu gcccccagac      120

agcgccaguc cacccuugug cucuucccug gagaccugag aaccaaucuc accgacaggc      180

agcuggcaga ggaauaccug uaccgcuaug guuacacucg gguggcagag augcguggag      240

agucgaaauc ucuggggccu gcgcugcugc uucuccagaa gcaacugucc cugcccgaga      300

ccggugagcu ggauagcgcc acgcugaagg ccaugcgaac cccacggugc ggggucccag      360

accugggcag auuccaaacc uuugagggcg accucaagug gcaccaccac aacaucaccu      420

auuggaucca aaacuacucg gaagacuugc cgcgggcggu gauugacgac gccuuugccc      480

gcgccuucgc acuguggagc gcggugacgc cgcucaccuu cacucgcgug uacagccggg      540

acgcagacau cgucauccag uuuggugucg cggagcacgg agacggguau cccuucgacg      600

ggaaggacgg gcuccuggca cacgccuuuc cuccuggccc cggcauucag ggagacgccc      660

auuucgacga ugacgaguug uggucccugg gcaagggcgu cgugguucca acucgguuug      720

gaaacgcaga uggcgcggcc ugccacuucc ccuucaucuu cgagggccgc uccuacucug      780

ccugcaccac cgacggucgc uccgacggcu ugcccuggug caguaccacg gccaacuacg      840

acaccgacga ccgguuuggc uucugcccca gcgagagacu cuacacccag gacggcaaug      900

cugaugggaa acccugccag uuuccauuca ucuuccaagg ccaauccuac uccgccugca      960

ccacggacgg ucgcuccgac ggcuaccgcu ggugcgccac caccgccaac uacgaccggg     1020

acaagcucuu cggcuucugc ccgacccgag cugacucgac ggugaugggg ggcaacucgg     1080

cgggggagcu gugcgucuuc cccuucacuu uccuggguaa ggaguacucg accuguacca     1140

gcgagggccg cggagauggg cgccucuggu gcgcuaccac cucgaacuuu gacagcgaca     1200

agaagugggg cuucugcccg gaccaaggau acaguuuguu ccucguggcg gcgcaugagu     1260

ucggccacgc gcugggcuua gaucauuccu cagugccgga ggcgcucaug uacccuaugu     1320

accgcuucac ugaggggccc cccuugcaua aggacgacgu gaauggcauc cggcaccucu     1380

augguccucg cccugaaccu gagccacggc cuccaaccac caccacaccg cagcccacgg     1440

cucccccgac ggucugcccc accggacccc ccacugucca ccccucagag cgccccacag     1500

cuggccccac aggucccccc ucagcuggcc ccacaggucc ccccacugcu ggcccuucua     1560

cggccacuac ugugccuuug aguccggugg acgaugccug caacgugaac aucuucgacg     1620

ccaucgcgga gauugggaac cagcuguauu uguucaagga ugggaaguac uggcgauucu     1680

cugagggcag ggggagccgg ccgcagggcc ccuuccuuau cgccgacaag uggcccgcgc     1740

ugccccgcaa gcuggacucg gucuuugagg agcggcucuc caagaagcuu uucuucuucu     1800

cugggcgcca ggugugggug uacacaggcg cgucggugcu gggcccgagg cgucuggaca     1860

agcugggccu gggagccgac guggcccagg ugaccggggc ccuccggagu ggcaggggga     1920

agaugcugcu guucagcggg cggcgccucu ggagguucga cgugaaggcg cagauggugg     1980

auccccggag cgccagcgag guggaccgga uguuccccgg ggugccuuug gacacgcacg     2040

acgucuucca guaccgagag aaagccuauu ucugccagga ccgcuucuac uggcgcguga     2100

guucccggag ugaguugaac cagguggacc aagugggcua cgugaccuau gacauccugc     2160

agugcccuga ggacuaggga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  2675
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (wt)

<400>  2675
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcauc       60

cagggguccu ggcugccuuc cucuucuuga gcuggacuca uugucgggcc cugccccuuc      120

ccaguggugg ugaugaagau gauuugucug aggaagaccu ccaguuugca gagcgcuacc      180

ugagaucaua cuaccauccu acaaaucucg cgggaauccu gaaggagaau gcagcaagcu      240

ccaugacuga gaggcuccga gaaaugcagu cuuucuucgg cuuagaggug acuggcaaac      300

uugacgauaa caccuuagau gucaugaaaa agccaagaug cgggguuccu gaugugggug      360

aauacaaugu uuucccucga acucuuaaau gguccaaaau gaauuuaacc uacagaauug      420

ugaauuacac cccugauaug acucauucug aagucgaaaa ggcauucaaa aaagccuuca      480

aaguuugguc cgauguaacu ccucugaauu uuaccagacu ucacgauggc auugcugaca      540

ucaugaucuc uuuuggaauu aaggagcaug gcgacuucua cccauuugau gggcccucug      600

gccugcuggc ucaugcuuuu ccuccugggc caaauuaugg aggagaugcc cauuuugaug      660

augaugaaac cuggacaagu aguuccaaag gcuacaacuu guuucuuguu gcugcgcaug      720

aguucggcca cuccuuaggu cuugaccacu ccaaggaccc uggagcacuc auguuuccua      780

ucuacaccua caccggcaaa agccacuuua ugcuuccuga ugacgaugua caagggaucc      840

agucucucua ugguccagga gaugaagacc ccaacccuaa acauccaaaa acgccagaca      900

aaugugaccc uuccuuaucc cuugaugcca uuaccagucu ccgaggagaa acaaugaucu      960

uuaaagacag auucuucugg cgccugcauc cucagcaggu ugaugcggag cuguuuuuaa     1020

cgaaaucauu uuggccagaa cuucccaacc guauugaugc ugcauaugag cacccuucuc     1080

augaccucau cuucaucuuc agagguagaa aauuuugggc ucuuaauggu uaugacauuc     1140

uggaagguua ucccaaaaaa auaucugaac ugggucuucc aaaagaaguu aagaagauaa     1200

gugcagcugu ucacuuugag gauacaggca agacucuccu guucucagga aaccaggucu     1260

ggagauauga ugauacuaac cauauuaugg auaaagacua uccgagacua auagaagaag     1320

acuucccagg aauuggugau aaaguagaug cugucuauga gaaaaauggu uauaucuauu     1380

uuuucaacgg acccauacag uuugaauaca gcaucuggag uaaccguauu guucgcguca     1440

ugccagcaaa uuccauuuug ugguguuaag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  2676
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (wt)

<400>  2676
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

cuccaaacac cacagaggac uaugacacga ccacagaguu ugacuauggg gaugcaacuc      120

cgugccagaa ggugaacgag agggccuuug gggcccaacu gcugcccccu cuguacuccu      180

ugguauuugu cauuggccug guuggaaaca uccugguggu ccugguccuu gugcaauaca      240

agaggcuaaa aaacaugacc agcaucuacc uccugaaccu ggccauuucu gaccugcucu      300

uccuguucac gcuucccuuc uggaucgacu acaaguugaa ggaugacugg guuuuuggug      360

augccaugug uaagauccuc ucuggguuuu auuacacagg cuuguacagc gagaucuuuu      420

ucaucauccu gcugacgauu gacagguacc uggccaucgu ccacgccgug uuugccuugc      480

gggcacggac cgucacuuuu ggugucauca ccagcaucau cauuugggcc cuggccaucu      540

uggcuuccau gccaggcuua uacuuuucca agacccaaug ggaauucacu caccacaccu      600

gcagccuuca cuuuccucac gaaagccuac gagaguggaa gcuguuucag gcucugaaac      660

ugaaccucuu ugggcuggua uugccuuugu uggucaugau caucugcuac acagggauua      720

uaaagauucu gcuaagacga ccaaaugaga agaaauccaa agcuguccgu uugauuuuug      780

ucaucaugau caucuuuuuu cucuuuugga cccccuacaa uuugacuaua cuuauuucug      840

uuuuccaaga cuuccuguuc acccaugagu gugagcagag cagacauuug gaccuggcug      900

ugcaagugac ggaggugauc gccuacacgc acugcugugu caacccagug aucuacgccu      960

ucguugguga gagguuccgg aaguaccugc ggcaguuguu ccacaggcgu guggcugugc     1020

accugguuaa auggcucccc uuccucuccg uggacaggcu ggagaggguc agcuccacau     1080

cucccuccac aggggagcau gaacucucug cuggguucug aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  2677
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (wt)

<400>  2677
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagga       60

ccuuggcuug ccugcugcuc cucggcugcg gauaccucgc ccauguucug gccgaggaag      120

ccgagauccc ccgcgaggug aucgagaggc uggcccgcag ucagauccac agcauccggg      180

accuccagcg acuccuggag auagacuccg uagggaguga ggauucuuug gacaccagcc      240

ugagagcuca cgggguccau gccacuaagc augugcccga gaagcggccc cugcccauuc      300

ggaggaagag aagcaucgag gaagcugucc ccgcugucug caagaccagg acggucauuu      360

acgagauucc ucggagucag gucgacccca cguccgccaa cuuccugauc uggcccccgu      420

gcguggaggu gaaacgcugc accggcugcu gcaacacgag cagugucaag ugccagcccu      480

cccgcgucca ccaccgcagc gucaaggugg ccaaggugga auacgucagg aagaagccaa      540

aauuaaaaga aguccaggug agguuagagg agcauuugga gugcgccugc gcgaccacaa      600

gccugaaucc ggauuaucgg gaagaggaca cgggaaggcc uagggaguca gguaaaaaac      660

ggaaaagaaa aagguuaaaa cccaccuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  2678
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (wt)

<400>  2678
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaauc       60

gcugcugggc gcucuuccug ucucucugcu gcuaccugcg ucuggucagc gccgaggggg      120

accccauucc cgaggagcuu uaugagaugc ugagugacca cucgauccgc uccuuugaug      180

aucuccaacg ccugcugcac ggagaccccg gagaggaaga uggggccgag uuggaccuga      240

acaugacccg cucccacucu ggaggcgagc uggagagcuu ggcucgugga agaaggagcc      300

uggguucccu gaccauugcu gagccggcca ugaucgccga gugcaagacg cgcaccgagg      360

uguucgagau cucccggcgc cucauagacc gcaccaacgc caacuuccug guguggccgc      420

ccugugugga ggugcagcgc ugcuccggcu gcugcaacaa ccgcaacgug cagugccgcc      480

ccacccaggu gcagcugcga ccuguccagg ugagaaagau cgagauugug cggaagaagc      540

caaucuuuaa gaaggccacg gugacgcugg aagaccaccu ggcaugcaag ugugagacag      600

uggcagcugc acggccugug acccgaagcc cgggggguuc ccaggagcag cgagccaaaa      660

cgccccaaac ucgggugacc auucggacgg ugcgaguccg ccggcccccc aagggcaagc      720

accggaaauu caagcacacg caugacaaga cggcacugaa ggagacccuu ggagccuagg      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  2679
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (wt)

<400>  2679
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

ucuucgggcu ucuccugcug acaucugccc uggccggcca gagacagggg acucaggcgg      120

aauccaaccu gaguaguaaa uuccaguuuu ccagcaacaa ggaacagaac ggaguacaag      180

auccucagca ugagagaauu auuacugugu cuacuaaugg aaguauucac agcccaaggu      240

uuccucauac uuauccaaga aauacggucu ugguauggag auuaguagca guagaggaaa      300

auguauggau acaacuuacg uuugaugaaa gauuugggcu ugaagaccca gaagaugaca      360

uaugcaagua ugauuuugua gaaguugagg aacccaguga uggaacuaua uuagggcgcu      420

ggugugguuc ugguacugua ccaggaaaac agauuucuaa aggaaaucaa auuaggauaa      480

gauuuguauc ugaugaauau uuuccuucug aaccaggguu cugcauccac uacaacauug      540

ucaugccaca auucacagaa gcugugaguc cuucagugcu acccccuuca gcuuugccac      600

uggaccugcu uaauaaugcu auaacugccu uuaguaccuu ggaagaccuu auucgauauc      660

uugaaccaga gagauggcag uuggacuuag aagaucuaua uaggccaacu uggcaacuuc      720

uuggcaaggc uuuuguuuuu ggaagaaaau ccagaguggu ggaucugaac cuucuaacag      780

aggagguaag auuauacagc ugcacaccuc guaacuucuc aguguccaua agggaagaac      840

uaaagagaac cgauaccauu uucuggccag guugucuccu gguuaaacgc ugugguggga      900

acugugccug uugucuccac aauugcaaug aaugucaaug ugucccaagc aaaguuacua      960

aaaaauacca cgagguccuu caguugagac caaagaccgg ugucagggga uugcacaaau     1020

cacucaccga cguggcccug gagcaccaug aggaguguga cugugugugc agagggagca     1080

caggaggaua gggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  2680
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (wt)

<400>  2680
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ggcucaucuu ugucuacacu cuaaucugcg caaacuuuug cagcugucgg gacacuucug      120

caaccccgca gagcgcaucc aucaaagcuu ugcgcaacgc caaccucagg cgagaugacu      180

uguaccgaag agaugagacc auccagguga aaggaaacgg cuacgugcag aguccuagau      240

ucccgaacag cuaccccagg aaccugcucc ugacauggcg gcuucacucu caggagaaua      300

cacggauaca gcuaguguuu gacaaucagu uuggauuaga ggaagcagaa aaugauaucu      360

guagguauga uuuuguggaa guugaagaua uauccgaaac caguaccauu auuagaggac      420

gauggugugg acacaaggaa guuccuccaa ggauaaaauc aagaacgaac caaauuaaaa      480

ucacauucaa guccgaugac uacuuugugg cuaaaccugg auucaagauu uauuauucuu      540

ugcuggaaga uuuccaaccc gcagcagcuu cagagaccaa cugggaaucu gucacaagcu      600

cuauuucagg gguauccuau aacucuccau caguaacgga ucccacucug auugcggaug      660

cucuggacaa aaaaauugca gaauuugaua caguggaaga ucugcucaag uacuucaauc      720

cagagucaug gcaagaagau cuugagaaua uguaucugga caccccucgg uaucgaggca      780

ggucauacca ugaccggaag ucaaaaguug accuggauag gcucaaugau gaugccaagc      840

guuacaguug cacucccagg aauuacucgg ucaauauaag agaagagcug aaguuggcca      900

auguggucuu cuuuccacgu ugccuccucg ugcagcgcug uggaggaaau uguggcugug      960

gaacugucaa cuggaggucc ugcacaugca auucagggaa aaccgugaaa aaguaucaug     1020

agguauuaca guuugagccu ggccacauca agaggagggg uagagcuaag accauggcuc     1080

uaguugacau ccaguuggau caccaugaac gaugugauug uaucugcagc ucaagaccac     1140

cucgauaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  2681
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (wt)

<400>  2681
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguca       60

cccacagcaa guuucccgcc gccgggauga gccgcccccu ggacaccagc cugcgccuca      120

agaccuucag cuccaagagc gaguaccagc ugguggugaa cgcagugcgc aagcugcagg      180

agagcggcuu cuacuggagc gcagugaccg gcggcgaggc gaaccugcug cucagugccg      240

agcccgccgg caccuuucug auccgcgaca gcucggacca gcgccacuuc uucacgcuca      300

gcgucaagac ccagucuggg accaagaacc ugcgcaucca gugugagggg ggcagcuucu      360

cucugcagag cgauccccgg agcacgcagc ccgugccccg cuucgacugc gugcucaagc      420

uggugcacca cuacaugccg cccccuggag cccccuccuu ccccucgcca ccuacugaac      480

ccuccuccga ggugcccgag cagccgucug cccagccacu cccugggagu ccccccagaa      540

gagccuauua caucuacucc gggggcgaga agaucccccu gguguugagc cggccccucu      600

ccuccaacgu ggccacucuu cagcaucucu gucggaagac cgucaacggc caccuggacu      660

ccuaugagaa agucacccag cugccggggc ccauucggga guuccuggac caguacgaug      720

ccccgcuuua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  2682
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (wt)

<400>  2682
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucc       60

ccucggcugg acagcucgcc cuguucgcuc uggguauugu guuggcugcg ugccaggccu      120

uggagaacag cacguccccg cugagugcag acccgcccgu ggcugcagca gugguguccc      180

auuuuaauga cugcccagau ucccacacuc aguucugcuu ccauggaacc ugcagguuuu      240

uggugcagga ggacaagcca gcaugugucu gccauucugg guacguuggu gcacgcugug      300

agcaugcgga ccuccuggcc gugguggcug ccagccagaa gaagcaggcc aucaccgccu      360

uggugguggu cuccaucgug gcccuggcug uccuuaucau cacaugugug cugauacacu      420

gcugccaggu ccgaaaacac ugugaguggu gccgggcccu caucugccgg cacgagaagc      480

ccagcgcccu ccugaaggga agaaccgcuu gcugccacuc agaaacagug gucugaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  2683
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (wt)

<400>  2683
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgc       60

ccuccgggcu gcggcugcug ccgcugcugc uaccgcugcu guggcuacug gugcugacgc      120

cuggccggcc ggccgcggga cuauccaccu gcaagacuau cgacauggag cuggugaagc      180

ggaagcgcau cgaggccauc cgcggccaga uccuguccaa gcugcggcuc gccagccccc      240

cgagccaggg ggaggugccg cccggcccgc ugcccgaggc cgugcucgcc cuguacaaca      300

gcacccgcga ccggguggcc ggggagagug cagaaccgga gcccgagccu gaggccgacu      360

acuacgccaa ggaggucacc cgcgugcuaa ugguggaaac ccacaacgaa aucuaugaca      420

aguucaagca gaguacacac agcauauaua uguucuucaa cacaucagag cuccgagaag      480

cgguaccuga acccguguug cucucccggg cagagcugcg ucugcugagg cucaaguuaa      540

aaguggagca gcacguggag cuguaccaga aauacagcaa caauuccugg cgauaccuca      600

gcaaccggcu gcuggcaccc agcgacucgc cagagugguu aucuuuugau gucaccggag      660

uugugcggca gugguugagc cguggagggg aaauugaggg cuuucgccuu agcgcccacu      720

gcuccuguga cagcagggau aacacacugc aaguggacau caacggguuc acuaccggcc      780

gccgagguga ccuggccacc auucauggca ugaaccggcc uuuccugcuu cucauggcca      840

ccccgcugga gagggcccag caucugcaaa gcucccggca ccgccgagcc cuggacacca      900

acuauugcuu cagcuccacg gagaagaacu gcugcgugcg gcagcuguac auugacuucc      960

gcaaggaccu cggcuggaag uggauccacg agcccaaggg cuaccaugcc aacuucugcc     1020

ucgggcccug ccccuacauu uggagccugg acacgcagua cagcaagguc cuggcccugu     1080

acaaccagca uaacccgggc gccucggcgg cgccgugcug cgugccgcag gcgcuggagc     1140

cgcugcccau cguguacuac gugggccgca agcccaaggu ggagcagcug uccaacauga     1200

ucgugcgcuc cugcaagugc agcugaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  2684
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (wt)

<400>  2684
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugugugcu gagcgcuuuu cugauccugc aucuggucac ggucgcgcuc agccugucua      120

ccugcagcac acucgauaug gaccaguuca ugcgcaagag gaucgaggcg auccgcgggc      180

agauccugag caagcugaag cucaccaguc ccccagaaga cuauccugag cccgaggaag      240

uccccccgga ggugauuucc aucuacaaca gcaccaggga cuugcuccag gagaaggcga      300

gccggagggc ggccgccugc gagcgcgaga ggagcgacga agaguacuac gccaaggagg      360

uuuacaaaau agacaugccg cccuucuucc ccuccgaaaa ugccaucccg cccacuuucu      420

acagacccua cuucagaauu guucgauuug acgucucagc aauggagaag aaugcuucca      480

auuuggugaa agcagaguuc agagucuuuc guuugcagaa cccaaaagcc agagugccug      540

aacaacggau ugagcuauau cagauucuca aguccaaaga uuuaacaucu ccaacccagc      600

gcuacaucga cagcaaaguu gugaaaacaa gagcagaagg cgaauggcuc uccuucgaug      660

uaacugaugc uguucaugaa uggcuucacc auaaagacag gaaccuggga uuuaaaauaa      720

gcuuacacug ucccugcugc acuuuuguac caucuaauaa uuacaucauc ccaaauaaaa      780

gugaagaacu agaagcaaga uuugcaggua uugauggcac cuccacauau accaguggug      840

aucagaaaac uauaaagucc acuaggaaaa aaaacagugg gaagacccca caucuccugc      900

uaauguuauu gcccuccuac agacuugagu cacaacagac caaccggcgg aagaagcgug      960

cuuuggaugc ggccuauugc uuuagaaaug ugcaggauaa uugcugccua cguccacuuu     1020

acauugauuu caagagggau cuagggugga aauggauaca cgaacccaaa ggguacaaug     1080

ccaacuucug ugcuggagca ugcccguauu uauggaguuc agacacucag cacagcaggg     1140

uccugagcuu auauaauacc auaaauccag aagcaucugc uucuccuugc ugcguguccc     1200

aagauuuaga accucuaacc auucucuacu acauuggcaa aacacccaag auugaacagc     1260

uuucuaauau gauuguaaag ucuugcaaau gcagcuaagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  2685
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (wt)

<400>  2685
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

ugcacuugca aagggcucug gugguccugg cccugcugaa cuuugccacg gucagccucu      120

cucuguccac uugcaccacc uuggacuucg gccacaucaa gaagaagagg guggaagcca      180

uuaggggaca gaucuugagc aagcucaggc ucaccagccc cccugagcca acggugauga      240

cccacguccc cuaucagguc cuggcccuuu acaacagcac ccgggagcug cuggaggaga      300

ugcaugggga gagggaggaa ggcugcaccc aggaaaacac cgagucggaa uacuaugcca      360

aagaaaucca uaaauucgac augauccagg ggcuggcgga gcacaacgaa cuggcugucu      420

gcccuaaagg aauuaccucc aagguuuucc gcuucaaugu guccucagug gagaaaaaua      480

gaaccaaccu auuccgagca gaauuccggg ucuugcgggu gcccaacccc agcucuaagc      540

ggaaugagca gaggaucgag cucuuccaga uccuucggcc agaugagcac auugccaaac      600

agcgcuauau cgguggcaag aaucugccca cacggggcac ugccgagugg cuguccuuug      660

augucacuga cacugugcgu gaguggcugu ugagaagaga guccaacuua ggucuagaaa      720

ucagcauuca cuguccaugu cacaccuuuc agcccaaugg agauauccug gaaaacauuc      780

acgaggugau ggaaaucaaa uucaaaggcg uggacaauga ggaugaccau ggccguggag      840

aucuggggcg ccucaagaag cagaaggauc accacaaccc ucaucuaauc cucaugauga      900

uucccccaca ccggcucgac aacccgggcc agggggguca gaggaagaag cgggcuuugg      960

acaccaauua cugcuuccgc aacuuggagg agaacugcug ugugcgcccc cucuacauug     1020

acuuccgaca ggaucugggc uggaaguggg uccaugaacc uaagggcuac uaugccaacu     1080

ucugcucagg cccuugccca uaccuccgca gugcagacac aacccacagc acggugcugg     1140

gacuguacaa cacucugaac ccugaagcau cugccucgcc uugcugcgug ccccaggacc     1200

uggagccccu gaccauccug uacuauguug ggaggacccc caaaguggag cagcucucca     1260

acaugguggu gaagucuugu aaauguagcu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2686
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (wt)

<400>  2686
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcgc       60

ccgucgccgu cugggccgcg cuggccgucg gacuggagcu cugggcugcg gcgcacgccu      120

ugcccgccca gguggcauuu acacccuacg ccccggagcc cgggagcaca ugccggcuca      180

gagaauacua ugaccagaca gcucagaugu gcugcagcaa augcucgccg ggccaacaug      240

caaaagucuu cuguaccaag accucggaca ccguguguga cuccugugag gacagcacau      300

acacccagcu cuggaacugg guucccgagu gcuugagcug uggcucccgc uguagcucug      360

accaggugga aacucaagcc ugcacucggg aacagaaccg caucugcacc ugcaggcccg      420

gcugguacug cgcgcugagc aagcaggagg ggugccggcu gugcgcgccg cugcgcaagu      480

gccgcccggg cuucggcgug gccagaccag gaacugaaac aucagacgug gugugcaagc      540

ccugugcccc ggggacguuc uccaacacga cuucauccac ggauauuugc aggccccacc      600

agaucuguaa cgugguggcc aucccuggga augcaagcau ggaugcaguc ugcacgucca      660

cgucccccac ccggaguaug gccccagggg caguacacuu accccagcca guguccacac      720

gaucccaaca cacgcagcca acuccagaac ccagcacugc uccaagcacc uccuuccugc      780

ucccaauggg ccccagcccc ccagcugaag ggagcacugg cgacuucgcu cuuccaguug      840

gacugauugu gggugugaca gccuuggguc uacuaauaau aggaguggug aacuguguca      900

ucaugaccca ggugaaaaag aagcccuugu gccugcagag agaagccaag gugccucacu      960

ugccugccga uaaggcccgg gguacacagg gccccgagca gcagcaccug cugaucacag     1020

cgccgagcuc cagcagcagc ucccuggaga gcucggccag ugcguuggac agaagggcgc     1080

ccacucggaa ccagccacag gcaccaggcg uggaggccag uggggccggg gaggcccggg     1140

ccagcaccgg gagcucagau ucuuccccug guggccaugg gacccagguc aaugucaccu     1200

gcaucgugaa cgucuguagc agcucugacc acagcucaca gugcuccucc caagccagcu     1260

ccacaauggg agacacagau uccagccccu cggagucccc gaaggacgag cagguccccu     1320

ucuccaagga ggaaugugcc uuucggucac agcuggagac gccagagacc cugcugggga     1380

gcaccgaaga gaagccccug ccccuuggag ugccugaugc ugggaugaag cccaguuaag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  2687
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (wt)

<400>  2687
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgg       60

ucaugaggcu guucccuugc uuccugcagc uccuggccgg gcuggcgcug ccugcugugc      120

ccccccagca gugggccuug ucugcuggga acggcucguc agagguggaa gugguacccu      180

uccaggaagu guggggccgc agcuacugcc gggcgcugga gaggcuggug gacgucgugu      240

ccgaguaccc cagcgaggug gagcacaugu ucagcccauc cugugucucc cugcugcgcu      300

gcaccggcug cugcggcgau gagaaucugc acugugugcc gguggagacg gccaauguca      360

ccaugcagcu ccuaaagauc cguucugggg accggcccuc cuacguggag cugacguucu      420

cucagcacgu ucgcugcgaa ugccggccuc ugcgggagaa gaugaagccg gaaaggagga      480

gacccaaggg cagggggaag aggaggagag agaagcagag acccacagac ugccaccugu      540

gcggcgaugc uguuccccgg agguaaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  2688
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (wt)

<400>  2688
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugacgg       60

acagacagac agacaccgcc cccagcccca gcuaccaccu ccuccccggc cggcggcgga      120

caguggacgc ggcggcgagc cgcgggcagg ggccggagcc cgcgcccgga ggcggggugg      180

agggggucgg ggcucgcggc gucgcacuga aacuuuucgu ccaacuucug ggcuguucuc      240

gcuucggagg agccgugguc cgcgcggggg aagccgagcc gagcggagcc gcgagaagug      300

cuagcucggg ccgggaggag ccgcagccgg aggaggggga ggaggaagaa gagaaggaag      360

aggagagggg gccgcagugg cgacucggcg cucggaagcc gggcucaugg acgggugagg      420

cggcggugug cgcagacagu gcuccagccg cgcgcgcucc ccaggcccug gcccgggccu      480

cgggccgggg aggaagagua gcucgccgag gcgccgagga gagcgggccg ccccacagcc      540

cgagccggag agggagcgcg agccgcgccg gccccggucg ggccuccgaa accaugaacu      600

uucugcuguc uugggugcau uggagccuug ccuugcugcu cuaccuccac caugccaagu      660

ggucccaggc ugcacccaug gcagaaggag gagggcagaa ucaucacgaa guggugaagu      720

ucauggaugu cuaucagcgc agcuacugcc auccaaucga gacccuggug gacaucuucc      780

aggaguaccc ugaugagauc gaguacaucu ucaagccauc cugugugccc cugaugcgau      840

gcgggggcug cugcaaugac gagggccugg agugugugcc cacugaggag uccaacauca      900

ccaugcagau uaugcggauc aaaccucacc aaggccagca cauaggagag augagcuucc      960

uacagcacaa caaaugugaa ugcagaccaa agaaagauag agcaagacaa gaaaaaaaau     1020

caguucgagg aaagggaaag gggcaaaaac gaaagcgcaa gaaaucccgg uauaaguccu     1080

ggagcgugua cguuggugcc cgcugcuguc uaaugcccug gagccucccu ggcccccauc     1140

ccugugggcc uugcucagag cggagaaagc auuuguuugu acaagauccg cagacgugua     1200

aauguuccug caaaaacaca gacucgcguu gcaaggcgag gcagcuugag uuaaacgaac     1260

guacuugcag augugacaag ccgaggcggu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2689
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (wt)

<400>  2689
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uucugcuguc uugggugcau uggagccuug ccuugcugcu cuaccuccac caugccaagu      120

ggucccaggc ugcacccaug gcagaaggag gagggcagaa ucaucacgaa guggugaagu      180

ucauggaugu cuaucagcgc agcuacugcc auccaaucga gacccuggug gacaucuucc      240

aggaguaccc ugaugagauc gaguacaucu ucaagccauc cugugugccc cugaugcgau      300

gcgggggcug cugcaaugac gagggccugg agugugugcc cacugaggag uccaacauca      360

ccaugcagau uaugcggauc aaaccucacc aaggccagca cauaggagag augagcuucc      420

uacagcacaa caaaugugaa ugcagaccaa agaaagauag agcaagacaa gaaaaaaaau      480

caguucgagg aaagggaaag gggcaaaaac gaaagcgcaa gaaaucccgg uauaaguccu      540

ggagcgugua cguuggugcc cgcugcuguc uaaugcccug gagccucccu ggcccccauc      600

ccugugggcc uugcucagag cggagaaagc auuuguuugu acaagauccg cagacgugua      660

aauguuccug caaaaacaca gacucgcguu gcaaggcgag gcagcuugag uuaaacgaac      720

guacuugcag augugacaag ccgaggcggu gaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  2690
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (wt)

<400>  2690
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

cucugcuccg ccgccugcug cucgccgcac uccugcagcu ggcccccgcc caggccccug      120

ucucccagcc ugaugccccu ggccaccaga ggaaaguggu gucauggaua gauguguaua      180

cucgcgcuac cugccagccc cgggaggugg uggugcccuu gacuguggag cucaugggca      240

ccguggccaa acagcuggug cccagcugcg ugacugugca gcgcuguggu ggcugcugcc      300

cugacgaugg ccuggagugu gugcccacug ggcagcacca aguccggaug cagauccuca      360

ugauccggua cccgagcagu cagcuggggg agaugucccu ggaagaacac agccagugug      420

aaugcagacc uaaaaaaaag gacagugcug ugaagccaga cagggcugcc acuccccacc      480

accgucccca gccccguucu guuccgggcu gggacucugc ccccggagca cccuccccag      540

cugacaucac ccaucccacu ccagccccag gccccucugc ccacgcugca cccagcacca      600

ccagcgcccu gacccccgga ccugccgcug ccgcugccga cgccgcagcu uccuccguug      660

ccaagggcgg ggcuuaggga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  2691
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (wt)

<400>  2691
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

ugcugggcuu cuucucugug gcguguucuc ugcucgccgc ugcgcugcuc ccggguccuc      120

gcgaggcgcc cgccgccgcc gccgccuucg aguccggacu cgaccucucg gacgcggagc      180

ccgacgcggg cgaggccacg gcuuaugcaa gcaaagaucu ggaggagcag uuacggucug      240

uguccagugu agaugaacuc augacuguac ucuacccaga auauuggaaa auguacaagu      300

gucagcuaag gaaaggaggc uggcaacaua acagagaaca ggccaaccuc aacucaagga      360

cagaagagac uauaaaauuu gcugcagcac auuauaauac agagaucuug aaaaguauug      420

auaaugagug gagaaagacu caaugcaugc cacgggaggu guguauagau guggggaagg      480

aguuuggagu cgcgacaaac accuucuuua aaccuccaug uguguccguc uacagaugug      540

gggguugcug caauagugag gggcugcagu gcaugaacac cagcacgagc uaccucagca      600

agacguuauu ugaaauuaca gugccucucu cucaaggccc caaaccagua acaaucaguu      660

uugccaauca cacuuccugc cgaugcaugu cuaaacugga uguuuacaga caaguucauu      720

ccauuauuag acguucccug ccagcaacac uaccacagug ucaggcagcg aacaagaccu      780

gccccaccaa uuacaugugg aauaaucaca ucugcagaug ccuggcucag gaagauuuua      840

uguuuuccuc ggaugcugga gaugacucaa cagauggauu ccaugacauc uguggaccaa      900

acaaggagcu ggaugaagag accugucagu gugucugcag agcggggcuu cggccugcca      960

gcuguggacc ccacaaagaa cuagacagaa acucaugcca gugugucugu aaaaacaaac     1020

ucuuccccag ccaauguggg gccaaccgag aauuugauga aaacacaugc caguguguau     1080

guaaaagaac cugccccaga aaucaacccc uaaauccugg aaaaugugcc ugugaaugua     1140

cagaaagucc acagaaaugc uuguuaaaag gaaagaaguu ccaccaccaa acaugcagcu     1200

guuacagacg gccauguacg aaccgccaga aggcuuguga gccaggauuu ucauauagug     1260

aagaagugug ucguuguguc ccuucauauu ggaaaagacc acaaaugagc uaaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  2692
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (wt)

<400>  2692
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguaca       60

gagagugggu aguggugaau guuuucauga uguuguacgu ccagcuggug cagggcucca      120

guaaugaaca uggaccagug aagcgaucau cucaguccac auuggaacga ucugaacagc      180

agaucagggc ugcuucuagu uuggaggaac uacuucgaau uacucacucu gaggacugga      240

agcuguggag augcaggcug aggcucaaaa guuuuaccag uauggacucu cgcucagcau      300

cccaucgguc cacuagguuu gcggcaacuu ucuaugacau ugaaacacua aaaguuauag      360

augaagaaug gcaaagaacu cagugcagcc cuagagaaac gugcguggag guggccagug      420

agcuggggaa gaguaccaac acauucuuca agcccccuug ugugaacgug uuccgaugug      480

guggcuguug caaugaagag agccuuaucu guaugaacac cagcaccucg uacauuucca      540

aacagcucuu ugagauauca gugccuuuga caucaguacc ugaauuagug ccuguuaaag      600

uugccaauca uacagguugu aagugcuugc caacagcccc ccgccaucca uacucaauua      660

ucagaagauc cauccagauc ccugaagaag aucgcuguuc ccauuccaag aaacucuguc      720

cuauugacau gcuaugggau agcaacaaau guaaaugugu uuugcaggag gaaaauccac      780

uugcuggaac agaagaccac ucucaucucc aggaaccagc ucucuguggg ccacacauga      840

uguuugacga agaucguugc gagugugucu guaaaacacc augucccaaa gaucuaaucc      900

agcaccccaa aaacugcagu ugcuuugagu gcaaagaaag ucuggagacc ugcugccaga      960

agcacaagcu auuucaccca gacaccugca gcugugagga cagaugcccc uuucauacca     1020

gaccaugugc aaguggcaaa acagcaugug caaagcauug ccgcuuucca aaggagaaaa     1080

gggcugccca ggggccccac agccgaaaga auccuugagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  2693
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt1)

<400>  2693
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcgacgagac cggcuucgag cacuccgggc ugugggugag cguccucgcc ggccugcugc      120

ucggggccug ccaggcccac cccaucccgg acuccagccc ccugcugcag uucggcggcc      180

aggugcgcca gcgguaccuc uacaccgacg acgcccagca gacggaggcc caccuggaga      240

uccgcgagga cgggaccgug ggcggggccg ccgaccaguc ccccgagagc cugcuccagc      300

ugaaggcgcu gaagcccggc gucauccaga uccucggggu gaagaccucc cgguuccugu      360

gccagcgccc ggacggcgcc cuguacggga gccuccacuu cgaccccgag gccugcuccu      420

uccgggagcu gcugcucgag gacggcuaca acguguacca gagcgaggcc cacggccugc      480

cccugcaccu ccccgggaac aaguccccgc accgcgaccc cgcgccccgg ggccccgccc      540

gcuuccugcc gcugcccggg cucccgcccg cccugcccga gccgcccggc auccuggcgc      600

cccagccgcc cgacgucggc agcuccgacc cccucagcau gguggggccc ucccagggcc      660

ggagccccuc cuacgccagc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  2694
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt1) R4749

<400>  2694
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuucccgcc ccugcuccug cugcucuucu ggggcguggu cucccacagc uuccccgcca      120

cccuggagac ccaggagcag gacguggacc uggugcagaa guaccucgag aaguacuaca      180

accugaagaa cgacgggcgc caggucgaga agcggcgcaa cuccggcccc gugguggaga      240

agcugaagca gaugcaggag uucuucgggc ucaaggucac gggcaagccc gacgccgaga      300

cccugaaggu gaugaagcag ccgcggugcg gggugcccga cgucgcgcag uucgugcuga      360

ccgagggcaa cccccgcugg gagcagaccc accucacgua ccggaucgag aacuacaccc      420

ccgaccugcc gcgcgccgac guggaccacg ccaucgagaa ggccuuccag cuguggagca      480

acgucacccc gcucaccuuc acgaaggugu ccgagggcca ggccgacauc augaucagcu      540

ucgugcgggg cgaccaccgc gacaacuccc ccuucgacgg gcccgggggc aaccuggcgc      600

acgccuucca gccggggccc ggcaucggcg gggacgccca cuucgacgag gacgagcggu      660

ggaccaacaa cuuccgcgag uacaaccugc accgggucgc cgcgcacgag cucggccaca      720

gccuggggcu gucccacagc accgacaucg gcgcccucau guaccccucc uacaccuuca      780

gcggcgacgu gcagcuggcc caggacgaca ucgacgggau ccaggccauc uacggccgcu      840

cccagaaccc cgugcagccg aucgggcccc agacgcccaa ggccugcgac agcaagcuga      900

ccuucgacgc gaucaccacc auccggggcg aggucauguu cuucaaggac cgcuucuaca      960

ugcggacgaa ccccuucuac ccggaggugg agcucaacuu caucuccgug uucuggcccc     1020

agcugcccaa cgggcuggag gccgccuacg aguucgccga ccgcgacgag guccgguucu     1080

ucaagggcaa caaguacugg gccgugcagg gccagaacgu gcuccacggg uaccccaagg     1140

acaucuacag cuccuucggc uucccgcgca ccgucaagca caucgacgcg gcccugagcg     1200

aggagaacac cgggaagacc uacuucuucg uggccaacaa guacuggcgg uacgacgagu     1260

acaagcgcuc cauggacccc ggcuacccca agaugaucgc ccacgacuuc cccgggaucg     1320

gccacaaggu cgacgccgug uucaugaagg acggcuucuu cuacuucuuc cacgggacgc     1380

ggcaguacaa guucgacccg aagaccaagc gcauccugac ccuccagaag gcgaacagcu     1440

gguucaacug ccgcaagaac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  2695
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt1) R4751

<400>  2695
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuucccgcc ccugcuccug cugcucuucu ggggcguggu cucccacagc uucgugcuga      120

ccgagggcaa cccccgcugg gagcagaccc accucacgua ccggaucgag aacuacaccc      180

ccgaccugcc gcgcgccgac guggaccacg ccaucgagaa ggccuuccag cuguggagca      240

acgucacccc gcucaccuuc acgaaggugu ccgagggcca ggccgacauc augaucagcu      300

ucgugcgggg cgaccaccgc gacaacuccc ccuucgacgg gcccgggggc aaccuggcgc      360

acgccuucca gccggggccc ggcaucggcg gggacgccca cuucgacgag gacgagcggu      420

ggaccaacaa cuuccgcgag uacaaccugc accgggucgc cgcgcacgag cucggccaca      480

gccuggggcu gucccacagc accgacaucg gcgcccucau guaccccucc uacaccuuca      540

gcggcgacgu gcagcuggcc caggacgaca ucgacgggau ccaggccauc uacggccgcu      600

cccagaaccc cgugcagccg aucgggcccc agacgcccaa ggccugcgac agcaagcuga      660

ccuucgacgc gaucaccacc auccggggcg aggucauguu cuucaaggac cgcuucuaca      720

ugcggacgaa ccccuucuac ccggaggugg agcucaacuu caucuccgug uucuggcccc      780

agcugcccaa cgggcuggag gccgccuacg aguucgccga ccgcgacgag guccgguucu      840

ucaagggcaa caaguacugg gccgugcagg gccagaacgu gcuccacggg uaccccaagg      900

acaucuacag cuccuucggc uucccgcgca ccgucaagca caucgacgcg gcccugagcg      960

aggagaacac cgggaagacc uacuucuucg uggccaacaa guacuggcgg uacgacgagu     1020

acaagcgcuc cauggacccc ggcuacccca agaugaucgc ccacgacuuc cccgggaucg     1080

gccacaaggu cgacgccgug uucaugaagg acggcuucuu cuacuucuuc cacgggacgc     1140

ggcaguacaa guucgacccg aagaccaagc gcauccugac ccuccagaag gcgaacagcu     1200

gguucaacug ccgcaagaac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  2696
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt1) R4537

<400>  2696
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

agaacauccu gaagauccuc auggacagcu acuccaagga gagcaagauc cagaccgugc      120

gccgggucac cuccgugagc cugcuggccg uguaccucac gaugaacacc uccagccugg      180

uccuggccaa gcccaucgag aacaccaacg acaccuccau caagaacgug gagaagcucc      240

gcaacgcgcc caacgaggag aacagcaaga agguggagga cuccaagaac gacaaggucg      300

agcacgugaa gaacaucgag gaggccaagg uggagcaggu cgcccccgag gugaagagca      360

aguccacgcu gcggagcgcc uccaucgcca acaccaacag cgagaaguac gacuucgagu      420

accugaacgg ccucuccuac accgagcuga ccaaccugau caagaacauc aaguggaacc      480

agaucaacgg gcucuucaac uacagcacgg gcucccagaa guucuucggg gacaagaacc      540

gcgugcaggc gaucaucaac gcccugcagg agagcggccg gaccuacacc gccaacgaca      600

ugaaggggau cgagaccuuc acggaggucc ugcgcgccgg cuucuaccuc ggcuacuaca      660

acgacgggcu guccuaccug aacgaccgga acuuccagga caagugcauc cccgcgauga      720

ucgccaucca gaagaacccc aacuucaagc ucggcaccgc cgugcaggac gaggugauca      780

ccagccuggg gaagcugauc ggcaacgcca gcgccaacgc ggaggucgug aacaacugcg      840

ugccgguccu caagcaguuc cgcgagaacc ugaaccagua cgcccccgac uacgugaagg      900

ggaccgccgu gaacgagcug aucaagggca ucgaguucga cuucuccggc gccgccuacg      960

agaaggacgu caagacgaug cccugguacg ggaagaucga ccccuucauc aacgagcuca     1020

aggcgcuggg ccuguacggg aacaucacca gcgccaccga gugggccucc gacgugggca     1080

ucuacuaccu cagcaaguuc ggccuguacu ccaccaaccg gaacgacauc gugcagagcc     1140

uggagaaggc cgucgacaug uacaaguacg ggaagaucgc cuucguggcg auggagcgca     1200

ucacguggga cuacgacggc aucgggucca acggcaagaa ggucgaccac gacaaguucc     1260

ucgacgacgc cgagaagcac uaccugccga agaccuacac cuucgacaac gggaccuuca     1320

ucauccgggc cggcgacaag gugagcgagg agaagaucaa gcgccuguac ugggccuccc     1380

gggaggugaa gagccaguuc caccgcgucg ugggcaacga caaggcccuc gaggugggga     1440

acgcggacga cguccugacg augaagaucu ucaacucccc cgaggaguac aaguucaaca     1500

ccaacaucaa cggcgugagc accgacaacg ggggccugua caucgagccg cgggggaccu     1560

ucuacacgua cgagcgcacc ccgcagcagu ccaucuucag ccucgaggag cuguuccggc     1620

acgaguacac ccacuaccug caggcccgcu accucgugga cggccugugg ggccaggggc     1680

cguucuacga gaagaaccgg cugaccuggu ucgacgaggg cacggccgag uucuucgccg     1740

gguccacccg caccagcggc guccuccccc ggaaguccau ccugggguac cuggcgaagg     1800

acaaggugga ccaccgcuac agccucaaga agacccugaa cuccggcuac gacgacagcg     1860

acuggauguu cuacaacuac ggcuucgccg uggcccacua ccuguacgag aaggacaugc     1920

ccacguucau caagaugaac aaggccaucc ugaacaccga cgucaagagc uacgacgaga     1980

ucaucaagaa gcucuccgac gacgccaaca agaacaccga guaccagaac cacauccagg     2040

agcuggcgga caaguaccag ggggccggca ucccccuggu gagcgacgac uaccucaagg     2100

accacgggua caagaaggcc uccgaggugu acagcgagau cuccaaggcc gccagccuga     2160

ccaacaccuc cgucacggcg gagaagagcc aguacuucaa caccuucacc cugcgcggca     2220

ccuacacggg cgagaccucc aagggggagu ucaaggacug ggacgagaug agcaagaagc     2280

ucgacggcac ccuggagucc cuggccaaga acagcugguc cggguacaag acccucacgg     2340

ccuacuucac caacuaccgg gugaccagcg acaacaaggu gcaguacgac gucguguucc     2400

acggcgugcu gaccgacaac gccgacaucu ccaacaacaa ggccccgauc gcgaagguca     2460

cggggcccag caccggcgcc gugggccgca acaucgaguu cuccgggaag gacagcaagg     2520

acgaggacgg caagaucgug agcuacgacu gggacuucgg ggacggcgcc accucccggg     2580

ggaagaacag cguccacgcc uacaagaagg cgggcaccua caacgugacg cugaagguga     2640

ccgacgacaa gggcgccacc gccaccgagu ccuucacgau cgagaucaag aacgaggaca     2700

ccaccacccc caucacgaag gagauggagc ccaacgacga caucaaggag gccaacgggc     2760

cgaucgucga gggcgugacc gugaaggggg accucaacgg cagcgacgac gccgacaccu     2820

ucuacuucga cgucaaggag gacggggacg ugaccaucga gcugcccuac uccggcagcu     2880

ccaacuucac guggcuggug uacaaggagg gcgacgacca gaaccacauc gcgagcggga     2940

ucgacaagaa caacuccaag gucggcaccu ucaagagcac caaggggcgc cacuacgugu     3000

ucaucuacaa gcacgacucc gccagcaaca ucuccuacag ccucaacauc aagggccugg     3060

ggaacgagaa gcugaaggag aaggagaaca acgacuccag cgacaaggcc accgugaucc     3120

ccaacuucaa cacgaccaug cagggcuccc uccugggcga cgacagccgg gacuacuacu     3180

ccuucgaggu caaggaggag ggggagguga acaucgagcu ggacaagaag gacgaguucg     3240

gcgugaccug gacccuccac cccgagagca acaucaacga ccgcaucacg uacgggcagg     3300

ucgacggcaa caaggugagc aacaagguga agcugcggcc gggcaaguac uaccugcucg     3360

ucuacaagua cuccgggagc ggcaacuacg agcugcgcgu gaacaaguga ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  2697
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt1) R4791

<400>  2697
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuccugu ucuccagcgc cuacuccauc gccaacacca      120

acagcgagaa guacgacuuc gaguaccuga acggccucuc cuacaccgag cugaccaacc      180

ugaucaagaa caucaagugg aaccagauca acgggcucuu caacuacagc acgggcuccc      240

agaaguucuu cggggacaag aaccgcgugc aggcgaucau caacgcccug caggagagcg      300

gccggaccua caccgccaac gacaugaagg ggaucgagac cuucacggag guccugcgcg      360

ccggcuucua ccucggcuac uacaacgacg ggcuguccua ccugaacgac cggaacuucc      420

aggacaagug cauccccgcg augaucgcca uccagaagaa ccccaacuuc aagcucggca      480

ccgccgugca ggacgaggug aucaccagcc uggggaagcu gaucggcaac gccagcgcca      540

acgcggaggu cgugaacaac ugcgugccgg uccucaagca guuccgcgag aaccugaacc      600

aguacgcccc cgacuacgug aaggggaccg ccgugaacga gcugaucaag ggcaucgagu      660

ucgacuucuc cggcgccgcc uacgagaagg acgucaagac gaugcccugg uacgggaaga      720

ucgaccccuu caucaacgag cucaaggcgc ugggccugua cgggaacauc accagcgcca      780

ccgagugggc cuccgacgug ggcaucuacu accucagcaa guucggccug uacuccacca      840

accggaacga caucgugcag agccuggaga aggccgucga cauguacaag uacgggaaga      900

ucgccuucgu ggcgauggag cgcaucacgu gggacuacga cggcaucggg uccaacggca      960

agaaggucga ccacgacaag uuccucgacg acgccgagaa gcacuaccug ccgaagaccu     1020

acaccuucga caacgggacc uucaucaucc gggccggcga caaggugagc gaggagaaga     1080

ucaagcgccu guacugggcc ucccgggagg ugaagagcca guuccaccgc gucgugggca     1140

acgacaaggc ccucgaggug gggaacgcgg acgacguccu gacgaugaag aucuucaacu     1200

cccccgagga guacaaguuc aacaccaaca ucaacggcgu gagcaccgac aacgggggcc     1260

uguacaucga gccgcggggg accuucuaca cguacgagcg caccccgcag caguccaucu     1320

ucagccucga ggagcuguuc cggcacgagu acacccacua ccugcaggcc cgcuaccucg     1380

uggacggccu guggggccag gggccguucu acgagaagaa ccggcugacc ugguucgacg     1440

agggcacggc cgaguucuuc gccgggucca cccgcaccag cggcguccuc ccccggaagu     1500

ccauccuggg guaccuggcg aaggacaagg uggaccaccg cuacagccuc aagaagaccc     1560

ugaacuccgg cuacgacgac agcgacugga uguucuacaa cuacggcuuc gccguggccc     1620

acuaccugua cgagaaggac augcccacgu ucaucaagau gaacaaggcc auccugaaca     1680

ccgacgucaa gagcuacgac gagaucauca agaagcucuc cgacgacgcc aacaagaaca     1740

ccgaguacca gaaccacauc caggagcugg cggacaagua ccagggggcc ggcauccccc     1800

uggugagcga cgacuaccuc aaggaccacg gguacaagaa ggccuccgag guguacagcg     1860

agaucuccaa ggccgccagc cugaccaaca ccuccgucac ggcggagaag agccaguacu     1920

ucaacaccuu cacccugcgc ggcaccuaca cgggcgagac cuccaagggg gaguucaagg     1980

acugggacga gaugagcaag aagcucgacg gcacccugga gucccuggcc aagaacagcu     2040

gguccgggua caagacccuc acggccuacu ucaccaacua ccgggugacc agcgacaaca     2100

aggugcagua cgacgucgug uuccacggcg ugcugaccga caacgccgac aucuccaaca     2160

acaaggcccc gaucgcgaag gucacggggc ccagcaccgg cgccgugggc cgcaacaucg     2220

aguucuccgg gaaggacagc aaggacgagg acggcaagau cgugagcuac gacugggacu     2280

ucggggacgg cgccaccucc cgggggaaga acagcgucca cgccuacaag aaggcgggca     2340

ccuacaacgu gacgcugaag gugaccgacg acaagggcgc caccgccacc gaguccuuca     2400

cgaucgagau caagaacgag gacaccacca cccccaucac gaaggagaug gagcccaacg     2460

acgacaucaa ggaggccaac gggccgaucg ucgagggcgu gaccgugaag ggggaccuca     2520

acggcagcga cgacgccgac accuucuacu ucgacgucaa ggaggacggg gacgugacca     2580

ucgagcugcc cuacuccggc agcuccaacu ucacguggcu gguguacaag gagggcgacg     2640

accagaacca caucgcgagc gggaucgaca agaacaacuc caaggucggc accuucaaga     2700

gcaccaaggg gcgccacuac guguucaucu acaagcacga cuccgccagc aacaucuccu     2760

acagccucaa caucaagggc cuggggaacg agaagcugaa ggagaaggag aacaacgacu     2820

ccagcgacaa ggccaccgug auccccaacu ucaacacgac caugcagggc ucccuccugg     2880

gcgacgacag ccgggacuac uacuccuucg aggucaagga ggagggggag gugaacaucg     2940

agcuggacaa gaaggacgag uucggcguga ccuggacccu ccaccccgag agcaacauca     3000

acgaccgcau cacguacggg caggucgacg gcaacaaggu gagcaacaag gugaagcugc     3060

ggccgggcaa guacuaccug cucgucuaca aguacuccgg gagcggcaac uacgagcugc     3120

gcgugaacaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  2698
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt1) R4793

<400>  2698
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuccugu ucuccagcgc cuacuccaug aagaagaaca      120

uccugaagau ccucauggac agcuacucca aggagagcaa gauccagacc gugcgccggg      180

ucaccuccgu gagccugcug gccguguacc ucacgaugaa caccuccagc cugguccugg      240

ccaagcccau cgagaacacc aacgacaccu ccaucaagaa cguggagaag cuccgcaacg      300

cgcccaacga ggagaacagc aagaaggugg aggacuccaa gaacgacaag gucgagcacg      360

ugaagaacau cgaggaggcc aagguggagc aggucgcccc cgaggugaag agcaagucca      420

cgcugcggag cgccucccgc cggcgccgga agcgcaucgc caacaccaac agcgagaagu      480

acgacuucga guaccugaac ggccucuccu acaccgagcu gaccaaccug aucaagaaca      540

ucaaguggaa ccagaucaac gggcucuuca acuacagcac gggcucccag aaguucuucg      600

gggacaagaa ccgcgugcag gcgaucauca acgcccugca ggagagcggc cggaccuaca      660

ccgccaacga caugaagggg aucgagaccu ucacggaggu ccugcgcgcc ggcuucuacc      720

ucggcuacua caacgacggg cuguccuacc ugaacgaccg gaacuuccag gacaagugca      780

uccccgcgau gaucgccauc cagaagaacc ccaacuucaa gcucggcacc gccgugcagg      840

acgaggugau caccagccug gggaagcuga ucggcaacgc cagcgccaac gcggaggucg      900

ugaacaacug cgugccgguc cucaagcagu uccgcgagaa ccugaaccag uacgcccccg      960

acuacgugaa ggggaccgcc gugaacgagc ugaucaaggg caucgaguuc gacuucuccg     1020

gcgccgccua cgagaaggac gucaagacga ugcccuggua cgggaagauc gaccccuuca     1080

ucaacgagcu caaggcgcug ggccuguacg ggaacaucac cagcgccacc gagugggccu     1140

ccgacguggg caucuacuac cucagcaagu ucggccugua cuccaccaac cggaacgaca     1200

ucgugcagag ccuggagaag gccgucgaca uguacaagua cgggaagauc gccuucgugg     1260

cgauggagcg caucacgugg gacuacgacg gcaucggguc caacggcaag aaggucgacc     1320

acgacaaguu ccucgacgac gccgagaagc acuaccugcc gaagaccuac accuucgaca     1380

acgggaccuu caucauccgg gccggcgaca aggugagcga ggagaagauc aagcgccugu     1440

acugggccuc ccgggaggug aagagccagu uccaccgcgu cgugggcaac gacaaggccc     1500

ucgagguggg gaacgcggac gacguccuga cgaugaagau cuucaacucc cccgaggagu     1560

acaaguucaa caccaacauc aacggcguga gcaccgacaa cgggggccug uacaucgagc     1620

cgcgggggac cuucuacacg uacgagcgca ccccgcagca guccaucuuc agccucgagg     1680

agcuguuccg gcacgaguac acccacuacc ugcaggcccg cuaccucgug gacggccugu     1740

ggggccaggg gccguucuac gagaagaacc ggcugaccug guucgacgag ggcacggccg     1800

aguucuucgc cggguccacc cgcaccagcg gcguccuccc ccggaagucc auccuggggu     1860

accuggcgaa ggacaaggug gaccaccgcu acagccucaa gaagacccug aacuccggcu     1920

acgacgacag cgacuggaug uucuacaacu acggcuucgc cguggcccac uaccuguacg     1980

agaaggacau gcccacguuc aucaagauga acaaggccau ccugaacacc gacgucaaga     2040

gcuacgacga gaucaucaag aagcucuccg acgacgccaa caagaacacc gaguaccaga     2100

accacaucca ggagcuggcg gacaaguacc agggggccgg caucccccug gugagcgacg     2160

acuaccucaa ggaccacggg uacaagaagg ccuccgaggu guacagcgag aucuccaagg     2220

ccgccagccu gaccaacacc uccgucacgg cggagaagag ccaguacuuc aacaccuuca     2280

cccugcgcgg caccuacacg ggcgagaccu ccaaggggga guucaaggac ugggacgaga     2340

ugagcaagaa gcucgacggc acccuggagu cccuggccaa gaacagcugg uccggguaca     2400

agacccucac ggccuacuuc accaacuacc gggugaccag cgacaacaag gugcaguacg     2460

acgucguguu ccacggcgug cugaccgaca acgccgacau cuccaacaac aaggccccga     2520

ucgcgaaggu cacggggccc agcaccggcg ccgugggccg caacaucgag uucuccggga     2580

aggacagcaa ggacgaggac ggcaagaucg ugagcuacga cugggacuuc ggggacggcg     2640

ccaccucccg ggggaagaac agcguccacg ccuacaagaa ggcgggcacc uacaacguga     2700

cgcugaaggu gaccgacgac aagggcgcca ccgccaccga guccuucacg aucgagauca     2760

agaacgagga caccaccacc cccaucacga aggagaugga gcccaacgac gacaucaagg     2820

aggccaacgg gccgaucguc gagggcguga ccgugaaggg ggaccucaac ggcagcgacg     2880

acgccgacac cuucuacuuc gacgucaagg aggacgggga cgugaccauc gagcugcccu     2940

acuccggcag cuccaacuuc acguggcugg uguacaagga gggcgacgac cagaaccaca     3000

ucgcgagcgg gaucgacaag aacaacucca aggucggcac cuucaagagc accaaggggc     3060

gccacuacgu guucaucuac aagcacgacu ccgccagcaa caucuccuac agccucaaca     3120

ucaagggccu ggggaacgag aagcugaagg agaaggagaa caacgacucc agcgacaagg     3180

ccaccgugau ccccaacuuc aacacgacca ugcagggcuc ccuccugggc gacgacagcc     3240

gggacuacua cuccuucgag gucaaggagg agggggaggu gaacaucgag cuggacaaga     3300

aggacgaguu cggcgugacc uggacccucc accccgagag caacaucaac gaccgcauca     3360

cguacgggca ggucgacggc aacaagguga gcaacaaggu gaagcugcgg ccgggcaagu     3420

acuaccugcu cgucuacaag uacuccggga gcggcaacua cgagcugcgc gugaacaagu     3480

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  2699
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt1)

<400>  2699
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugaagau cauccucaac cgcggcaaga ccaugaagcg gaagugccug agcaagcgcc      120

ugaugcucgc caucaccaug gccacgaucu ucaccgugaa cuccacccug cccaucuacg      180

cggccgucga caagaacaac gccaccgccg ccgugcagaa cgagagcaag cgguacacgg      240

uguccuaccu gaagacccuc aacuacuacg accuggucga ccugcucgug aagaccgaga      300

ucgagaaccu gccggaccug uuccaguaca gcuccgacgc gaaggaguuc uacgggaaca      360

agacccgcau gagcuucauc auggacgaga ucggccggcg cgcgccccag uacacggaga      420

ucgaccacaa ggggaucccc acccucgugg aggucgugcg ggccggcuuc uaccuggggu      480

uccacaacaa ggagcugaac gagaucaaca agcgcuccuu caaggagcgg gugaucccca      540

gcauccucgc cauccagaag aacccgaacu ucaagcuggg caccgagguc caggacaaga      600

ucguguccgc caccggccug cucgccggga acgagacggc cccgcccgag guggucaaca      660

acuucacccc cauccugcag gacugcauca agaacaucga ccgcuacgcc cuggacgacc      720

ucaagagcaa ggcccuguuc aacgugcugg cggccccgac cuacgacauc accgaguacc      780

uccgggccac gaaggagaag cccgagaaca cccccuggua cggcaagauc gacggguuca      840

ucaacgagcu gaagaagcug gcccucuacg gcaagaucaa cgacaacaac uccuggauca      900

ucgacaacgg gaucuaccac aucgcgcccc ugggcaagcu gcacagcaac aacaagaucg      960

gcaucgagac ccucaccgag gugaugaagg ucuacccgua ccuguccaug cagcaccucc     1020

agagcgccga ccagaucaag cgccacuacg acuccaagga cgccgagggg aacaagaucc     1080

cccuggacaa guucaagaag gagggcaagg agaaguacug ccccaagacg uacaccuucg     1140

acgacgggaa ggugaucauc aaggccggcg cccgggugga ggaggagaag gucaagcgcc     1200

uguacugggc cagcaaggag gugaacuccc aguucuuccg gguguacggc aucgacaagc     1260

cccuggagga ggggaacccg gacgacaucc ucaccauggu caucuacaac agccccgagg     1320

aguacaagcu gaacuccgug cuguacggcu acgacaccaa caacgggggc auguacaucg     1380

agcccgaggg gacguucuuc accuacgagc gcgaggcgca ggagagcacc uacacccucg     1440

aggagcuguu ccggcacgag uacacgcacu accugcaggg ccgcuacgcc gugcccggcc     1500

agugggggcg gaccaagcuc uacgacaacg accgccugac cugguacgag gagggcgggg     1560

ccgagcuguu cgccggcagc acccggacgu ccgggauccu cccgcgcaag agcaucgucu     1620

ccaacaucca caacaccacc cgcaacaacc gguacaagcu gagcgacacc gugcacucca     1680

aguacggcgc cagcuucgag uucuacaacu acgcgugcau guucauggac uacauguaca     1740

acaaggacau gggcauccug aacaagcuca acgaccuggc caagaacaac gacgucgacg     1800

gguacgacaa cuacauccgc gaccugucca gcaacuacgc ccugaacgac aaguaccagg     1860

accacaugca ggagcggauc gacaacuacg agaaccucac ggugcccuuc guggccgacg     1920

acuaccuggu ccgccacgcg uacaagaacc ccaacgagau cuacuccgag aucagcgagg     1980

uggccaagcu gaaggacgcc aaguccgagg ugaagaaguc ccaguacuuc agcaccuuca     2040

cccuccgggg cagcuacacc gggggcgccu ccaaggggaa gcuggaggac cagaaggcca     2100

ugaacaaguu caucgacgac agccugaaga agcucgacac cuacuccugg agcggcuaca     2160

agacgcugac cgcguacuuc accaacuaca aggucgacuc cagcaaccgc gugaccuacg     2220

acguggucuu ccacggcuac cugcccaacg agggggacag caagaacucc cucccguacg     2280

gcaagaucaa cgggacguac aagggcaccg agaaggagaa gaucaaguuc agcuccgagg     2340

gcagcuucga ccccgacggg aagaucgugu ccuacgagug ggacuucggc gacgggaaca     2400

agagcaacga ggagaacccc gagcacuccu acgacaaggu gggcaccuac accgucaagc     2460

ugaaggugac ggacgacaag ggggagagcu ccgugagcac caccaccgcc gagaucaagg     2520

accuguccga gaacaagcuc cccgucaucu acaugcacgu gcccaagagc ggcgcccuga     2580

accagaaggu ggucuucuac ggcaagggga cguacgaccc cgacggcucc aucgccgggu     2640

accaguggga cuucggcgac gggagcgacu ucuccagcga gcagaacccc ucccacgugu     2700

acaccaagaa gggcgaguac accgugaccc ugcgggucau ggacagcagc ggccagaugu     2760

ccgagaagac gaugaagauc aagaucaccg acccggugua ccccaucggg accgagaagg     2820

agcccaacaa cagcaaggag accgccuccg gccccaucgu gccggggauc cccgucagcg     2880

gcacgaucga gaacaccucc gaccaggacu acuucuacuu cgacgugauc acccccgggg     2940

aggugaagau cgacaucaac aagcucggcu acggcggggc gaccuggguc guguacgacg     3000

agaacaacaa cgccgugagc uacgccacgg acgacggcca gaaccugucc gggaaguuca     3060

aggccgacaa gcccggccgc uacuacaucc accuguacau guucaacggg agcuacaugc     3120

cguaccggau caacaucgag ggcuccgucg gccgcugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  2700
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt1) R4538

<400>  2700
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

gcaagugccu gagcaagcgg cucaugcugg ccaucaccau ggccaccauc uucacgguga      120

acuccacccu gcccaucuac gcggccgucg acaagaacaa cgccaccgcc gccgugcaga      180

acgagagcaa gcgcuacacc guguccuacc ucaagacgcu gaacuacuac gaccuggucg      240

accuccuggu gaagaccgag aucgagaacc ugcccgaccu cuuccaguac agcuccgacg      300

cgaaggaguu cuacggcaac aagacccgga ugagcuucau cauggacgag aucgggcgcc      360

gggccccgca guacaccgag aucgaccaca agggcauccc cacgcuggug gaggucgugc      420

gcgccggguu cuaccugggc uuccacaaca aggagcucaa cgagaucaac aagcgguccu      480

ucaaggagcg cgugaucccc agcauccugg ccauccagaa gaacccgaac uucaagcugg      540

ggaccgaggu ccaggacaag aucguguccg cgaccggccu ccuggccggc aacgagaccg      600

ccccgcccga gguggucaac aacuucacgc ccauccugca ggacugcauc aagaacaucg      660

accgguacgc ccucgacgac cugaagagca aggcccuguu caacgugcuc gcggccccga      720

ccuacgacau caccgaguac cugcgcgcca ccaaggagaa gcccgagaac acgccguggu      780

acgggaagau cgacggcuuc aucaacgagc ugaagaagcu cgcccuguac gggaagauca      840

acgacaacaa cuccuggauc aucgacaacg gcaucuacca caucgccccc cuggggaagc      900

uccacagcaa caacaagauc ggcaucgaga cccugaccga ggugaugaag gucuacccgu      960

accuguccau gcagcaccuc cagagcgcgg accagaucaa gcggcacuac gacuccaagg     1020

acgccgaggg caacaagauc ccccuggaca aguucaagaa ggaggggaag gagaaguacu     1080

gccccaagac cuacacguuc gacgacggca aggugaucau caaggccggg gcccgcgugg     1140

aggaggagaa ggucaagcgg cuguacuggg ccagcaagga ggugaacucc caguucuucc     1200

gcguguacgg caucgacaag ccccucgagg agggcaaccc ggacgacauc cugaccaugg     1260

ucaucuacaa cagccccgag gaguacaagc ugaacuccgu gcucuacggg uacgacacca     1320

acaacggcgg gauguacauc gagcccgagg gcaccuucuu cacguacgag cgggaggcgc     1380

aggagagcac cuacacccug gaggagcugu uccgccacga guacacccac uaccuccagg     1440

ggcgguacgc cgugcccggc caguggggcc gcacgaagcu guacgacaac gaccggcuga     1500

ccugguacga ggagggcggc gccgagcucu ucgccgggag cacccgcacc uccgggaucc     1560

ugccgcggaa gagcaucguc uccaacaucc acaacacgac ccgcaacaac cgcuacaagc     1620

ugagcgacac cgugcacucc aaguacgggg ccagcuucga guucuacaac uacgcgugca     1680

uguucaugga cuacauguac aacaaggaca ugggcauccu caacaagcug aacgaccugg     1740

ccaagaacaa cgacgucgac ggcuacgaca acuacauccg ggaccugucc agcaacuacg     1800

cccucaacga caaguaccag gaccacaugc aggagcgcau cgacaacuac gagaaccuga     1860

ccgugcccuu cguggccgac gacuaccugg uccggcacgc guacaagaac cccaacgaga     1920

ucuacuccga gaucagcgag guggccaagc ucaaggacgc caaguccgag gugaagaaga     1980

gccaguacuu cuccacguuc acccugcgcg ggagcuacac cggcggggcc uccaagggca     2040

agcuggagga ccagaaggcc augaacaagu ucaucgacga cagccucaag aagcuggaca     2100

ccuacuccug gagcggguac aagacccuga cggcguacuu caccaacuac aaggucgacu     2160

ccagcaaccg ggugaccuac gacguggucu uccacggcua ccuccccaac gagggcgaca     2220

gcaagaacuc ccugccguac gggaagauca acggcaccua caaggggacg gagaaggaga     2280

agaucaaguu cagcuccgag ggcagcuucg accccgacgg caagaucgug uccuacgagu     2340

gggacuucgg ggacggcaac aagagcaacg aggagaaccc cgagcacucc uacgacaagg     2400

uggggaccua caccgucaag cugaagguga ccgacgacaa gggcgagagc uccgugagca     2460

cgaccaccgc cgagaucaag gaccucuccg agaacaagcu gcccgucauc uacaugcacg     2520

ugccgaagag cggggcccug aaccagaagg uggucuucua cggcaagggc accuacgacc     2580

ccgacggguc caucgccggc uaccaguggg acuucgggga cggcagcgac uucuccagcg     2640

agcagaaccc cucccacgug uacacgaaga agggggagua caccgugacc cuccgcguca     2700

uggacagcag cggccagaug uccgagaaga ccaugaagau caagaucacg gacccggugu     2760

accccaucgg caccgagaag gagcccaaca acagcaagga gaccgccucc gggcccaucg     2820

ugccgggcau ccccgucagc gggaccaucg agaacacguc cgaccaggac uacuucuacu     2880

ucgacgugau cacccccggc gaggugaaga ucgacaucaa caagcugggg uacggcggcg     2940

cgaccugggu cguguacgac gagaacaaca acgccgugag cuacgccacc gacgacgggc     3000

agaaccuguc cggcaaguuc aaggccgaca agcccgggcg guacuacauc caccucuaca     3060

uguucaacgg cagcuacaug ccguaccgca ucaacaucga gggguccguc ggccggugag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  2701
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt1) R4790

<400>  2701
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuccugu ucuccagcgc cuacuccgug cagaacgaga      120

gcaagcgcua caccgugucc uaccucaaga cgcugaacua cuacgaccug gucgaccucc      180

uggugaagac cgagaucgag aaccugcccg accucuucca guacagcucc gacgcgaagg      240

aguucuacgg caacaagacc cggaugagcu ucaucaugga cgagaucggg cgccgggccc      300

cgcaguacac cgagaucgac cacaagggca uccccacgcu gguggagguc gugcgcgccg      360

gguucuaccu gggcuuccac aacaaggagc ucaacgagau caacaagcgg uccuucaagg      420

agcgcgugau ccccagcauc cuggccaucc agaagaaccc gaacuucaag cuggggaccg      480

agguccagga caagaucgug uccgcgaccg gccuccuggc cggcaacgag accgccccgc      540

ccgagguggu caacaacuuc acgcccaucc ugcaggacug caucaagaac aucgaccggu      600

acgcccucga cgaccugaag agcaaggccc uguucaacgu gcucgcggcc ccgaccuacg      660

acaucaccga guaccugcgc gccaccaagg agaagcccga gaacacgccg ugguacggga      720

agaucgacgg cuucaucaac gagcugaaga agcucgcccu guacgggaag aucaacgaca      780

acaacuccug gaucaucgac aacggcaucu accacaucgc cccccugggg aagcuccaca      840

gcaacaacaa gaucggcauc gagacccuga ccgaggugau gaaggucuac ccguaccugu      900

ccaugcagca ccuccagagc gcggaccaga ucaagcggca cuacgacucc aaggacgccg      960

agggcaacaa gaucccccug gacaaguuca agaaggaggg gaaggagaag uacugcccca     1020

agaccuacac guucgacgac ggcaagguga ucaucaaggc cggggcccgc guggaggagg     1080

agaaggucaa gcggcuguac ugggccagca aggaggugaa cucccaguuc uuccgcgugu     1140

acggcaucga caagccccuc gaggagggca acccggacga cauccugacc auggucaucu     1200

acaacagccc cgaggaguac aagcugaacu ccgugcucua cggguacgac accaacaacg     1260

gcgggaugua caucgagccc gagggcaccu ucuucacgua cgagcgggag gcgcaggaga     1320

gcaccuacac ccuggaggag cuguuccgcc acgaguacac ccacuaccuc caggggcggu     1380

acgccgugcc cggccagugg ggccgcacga agcuguacga caacgaccgg cugaccuggu     1440

acgaggaggg cggcgccgag cucuucgccg ggagcacccg caccuccggg auccugccgc     1500

ggaagagcau cgucuccaac auccacaaca cgacccgcaa caaccgcuac aagcugagcg     1560

acaccgugca cuccaaguac ggggccagcu ucgaguucua caacuacgcg ugcauguuca     1620

uggacuacau guacaacaag gacaugggca uccucaacaa gcugaacgac cuggccaaga     1680

acaacgacgu cgacggcuac gacaacuaca uccgggaccu guccagcaac uacgcccuca     1740

acgacaagua ccaggaccac augcaggagc gcaucgacaa cuacgagaac cugaccgugc     1800

ccuucguggc cgacgacuac cugguccggc acgcguacaa gaaccccaac gagaucuacu     1860

ccgagaucag cgagguggcc aagcucaagg acgccaaguc cgaggugaag aagagccagu     1920

acuucuccac guucacccug cgcgggagcu acaccggcgg ggccuccaag ggcaagcugg     1980

aggaccagaa ggccaugaac aaguucaucg acgacagccu caagaagcug gacaccuacu     2040

ccuggagcgg guacaagacc cugacggcgu acuucaccaa cuacaagguc gacuccagca     2100

accgggugac cuacgacgug gucuuccacg gcuaccuccc caacgagggc gacagcaaga     2160

acucccugcc guacgggaag aucaacggca ccuacaaggg gacggagaag gagaagauca     2220

aguucagcuc cgagggcagc uucgaccccg acggcaagau cguguccuac gagugggacu     2280

ucggggacgg caacaagagc aacgaggaga accccgagca cuccuacgac aaggugggga     2340

ccuacaccgu caagcugaag gugaccgacg acaagggcga gagcuccgug agcacgacca     2400

ccgccgagau caaggaccuc uccgagaaca agcugcccgu caucuacaug cacgugccga     2460

agagcggggc ccugaaccag aagguggucu ucuacggcaa gggcaccuac gaccccgacg     2520

gguccaucgc cggcuaccag ugggacuucg gggacggcag cgacuucucc agcgagcaga     2580

accccuccca cguguacacg aagaaggggg aguacaccgu gacccuccgc gucauggaca     2640

gcagcggcca gauguccgag aagaccauga agaucaagau cacggacccg guguacccca     2700

ucggcaccga gaaggagccc aacaacagca aggagaccgc cuccgggccc aucgugccgg     2760

gcauccccgu cagcgggacc aucgagaaca cguccgacca ggacuacuuc uacuucgacg     2820

ugaucacccc cggcgaggug aagaucgaca ucaacaagcu gggguacggc ggcgcgaccu     2880

gggucgugua cgacgagaac aacaacgccg ugagcuacgc caccgacgac gggcagaacc     2940

uguccggcaa guucaaggcc gacaagcccg ggcgguacua cauccaccuc uacauguuca     3000

acggcagcua caugccguac cgcaucaaca ucgagggguc cgucggccgg ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  2702
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt1) R4792

<400>  2702
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuccugu ucuccagcgc cuacuccaug aagcgcaagu      120

gccugagcaa gcggcucaug cuggccauca ccauggccac caucuucacg gugaacucca      180

cccugcccau cuacgcggcc gucgacaaga acaacgccac cgccgcccgc cggcgccgga      240

agcgcgugca gaacgagagc aagcgcuaca ccguguccua ccucaagacg cugaacuacu      300

acgaccuggu cgaccuccug gugaagaccg agaucgagaa ccugcccgac cucuuccagu      360

acagcuccga cgcgaaggag uucuacggca acaagacccg gaugagcuuc aucauggacg      420

agaucgggcg ccgggccccg caguacaccg agaucgacca caagggcauc cccacgcugg      480

uggaggucgu gcgcgccggg uucuaccugg gcuuccacaa caaggagcuc aacgagauca      540

acaagcgguc cuucaaggag cgcgugaucc ccagcauccu ggccauccag aagaacccga      600

acuucaagcu ggggaccgag guccaggaca agaucguguc cgcgaccggc cuccuggccg      660

gcaacgagac cgccccgccc gaggugguca acaacuucac gcccauccug caggacugca      720

ucaagaacau cgaccgguac gcccucgacg accugaagag caaggcccug uucaacgugc      780

ucgcggcccc gaccuacgac aucaccgagu accugcgcgc caccaaggag aagcccgaga      840

acacgccgug guacgggaag aucgacggcu ucaucaacga gcugaagaag cucgcccugu      900

acgggaagau caacgacaac aacuccugga ucaucgacaa cggcaucuac cacaucgccc      960

cccuggggaa gcuccacagc aacaacaaga ucggcaucga gacccugacc gaggugauga     1020

aggucuaccc guaccugucc augcagcacc uccagagcgc ggaccagauc aagcggcacu     1080

acgacuccaa ggacgccgag ggcaacaaga ucccccugga caaguucaag aaggagggga     1140

aggagaagua cugccccaag accuacacgu ucgacgacgg caaggugauc aucaaggccg     1200

gggcccgcgu ggaggaggag aaggucaagc ggcuguacug ggccagcaag gaggugaacu     1260

cccaguucuu ccgcguguac ggcaucgaca agccccucga ggagggcaac ccggacgaca     1320

uccugaccau ggucaucuac aacagccccg aggaguacaa gcugaacucc gugcucuacg     1380

gguacgacac caacaacggc gggauguaca ucgagcccga gggcaccuuc uucacguacg     1440

agcgggaggc gcaggagagc accuacaccc uggaggagcu guuccgccac gaguacaccc     1500

acuaccucca ggggcgguac gccgugcccg gccagugggg ccgcacgaag cuguacgaca     1560

acgaccggcu gaccugguac gaggagggcg gcgccgagcu cuucgccggg agcacccgca     1620

ccuccgggau ccugccgcgg aagagcaucg ucuccaacau ccacaacacg acccgcaaca     1680

accgcuacaa gcugagcgac accgugcacu ccaaguacgg ggccagcuuc gaguucuaca     1740

acuacgcgug cauguucaug gacuacaugu acaacaagga caugggcauc cucaacaagc     1800

ugaacgaccu ggccaagaac aacgacgucg acggcuacga caacuacauc cgggaccugu     1860

ccagcaacua cgcccucaac gacaaguacc aggaccacau gcaggagcgc aucgacaacu     1920

acgagaaccu gaccgugccc uucguggccg acgacuaccu gguccggcac gcguacaaga     1980

accccaacga gaucuacucc gagaucagcg agguggccaa gcucaaggac gccaaguccg     2040

aggugaagaa gagccaguac uucuccacgu ucacccugcg cgggagcuac accggcgggg     2100

ccuccaaggg caagcuggag gaccagaagg ccaugaacaa guucaucgac gacagccuca     2160

agaagcugga caccuacucc uggagcgggu acaagacccu gacggcguac uucaccaacu     2220

acaaggucga cuccagcaac cgggugaccu acgacguggu cuuccacggc uaccucccca     2280

acgagggcga cagcaagaac ucccugccgu acgggaagau caacggcacc uacaagggga     2340

cggagaagga gaagaucaag uucagcuccg agggcagcuu cgaccccgac ggcaagaucg     2400

uguccuacga gugggacuuc ggggacggca acaagagcaa cgaggagaac cccgagcacu     2460

ccuacgacaa gguggggacc uacaccguca agcugaaggu gaccgacgac aagggcgaga     2520

gcuccgugag cacgaccacc gccgagauca aggaccucuc cgagaacaag cugcccguca     2580

ucuacaugca cgugccgaag agcggggccc ugaaccagaa gguggucuuc uacggcaagg     2640

gcaccuacga ccccgacggg uccaucgccg gcuaccagug ggacuucggg gacggcagcg     2700

acuucuccag cgagcagaac cccucccacg uguacacgaa gaagggggag uacaccguga     2760

cccuccgcgu cauggacagc agcggccaga uguccgagaa gaccaugaag aucaagauca     2820

cggacccggu guaccccauc ggcaccgaga aggagcccaa caacagcaag gagaccgccu     2880

ccgggcccau cgugccgggc auccccguca gcgggaccau cgagaacacg uccgaccagg     2940

acuacuucua cuucgacgug aucacccccg gcgaggugaa gaucgacauc aacaagcugg     3000

gguacggcgg cgcgaccugg gucguguacg acgagaacaa caacgccgug agcuacgcca     3060

ccgacgacgg gcagaaccug uccggcaagu ucaaggccga caagcccggg cgguacuaca     3120

uccaccucua cauguucaac ggcagcuaca ugccguaccg caucaacauc gagggguccg     3180

ucggccggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  2703
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt1)

<400>  2703
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg ccgcguucgc caugccccug ccgccccacc      120

ccggccaccc cggguacauc aacuucagcu acgaggugcu caccccgcug aagugguacc      180

aguccauccg cccgcccuac cccagcuacg gcuacgagcc caugggcggg uggcugcacc      240

accagaucau ccccguccuc ucccagcagc acccgcccac gcacacccug cagccgcacc      300

accacauccc cguggugccc gcccagcagc ccgucauccc ccagcagccc augaugcccg      360

ugcccggcca gcacagcaug accccgaucc agcaccacca gcccaaccug cccccgccgg      420

cccagcagcc cuaccagccc cagcccgugc agccccagcc ccaccagccc augcagccgc      480

agccgcccgu ccaccccaug cagccgcucc cgccccagcc cccgcugccg cccauguucc      540

ccaugcagcc ccugccgccc augcuccccg accugacccu ggaggccugg cccuccacgg      600

acaagaccaa gcgggaggag guggacugag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  2704
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt1)

<400>  2704
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccgcccca ccccggccac cccggguaca ucaacuucag cuacgaggug cucaccccgc      120

ugaaguggua ccaguccauc cgcccgcccu accccagcua cggcuacgag cccaugggcg      180

gguggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  2705
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt1)

<400>  2705
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccgcccca ccccggccac cccggguaca ucaacuucag cuacgaggug cucaccccgc      120

ugaaguggua ccaguccauc cgcccgccgc ccaugcuccc cgaccugacc cuggaggccu      180

ggcccuccac ggacaagacc aagcgggagg agguggacug aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  2706
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt1)

<400>  2706
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcccc gcggacccug guccuccugc ugagcggcgc gcucgcccug acccagacgu      120

gggccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc agcuacgagg      180

ugcucacccc gcugaagugg uaccagucca uccgcccgcc cuaccccagc uacggcuacg      240

agcccauggg cgggugguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  2707
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt1)

<400>  2707
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcccc gcggacccug guccuccugc ugagcggcgc gcucgcccug acccagacgu      120

gggccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc agcuacgagg      180

ugcucacccc gcugaagugg uaccagucca uccgcccgcc gcccaugcuc cccgaccuga      240

cccuggaggc cuggcccucc acggacaaga ccaagcggga ggagguggac ugaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  2708
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt1)

<400>  2708
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cucguggggg ccgcguucgc caugccccug ccgccccacc      120

ccggccaccc cggguacauc aacuucagcu acgagguccu gaccccgcuc aagugguacc      180

aguccaugau ccgcccgccc uacagcuccu acggcuacga gcccaugggc ggguggcugc      240

accaccagau cauccccgug gugagccagc agcacccccu gacgcacacc cuccaguccc      300

accaccacau ccccgucgug cccgcccagc agccgcgggu gcgccagcag gcccugaugc      360

ccguccccgg ccagcagagc augaccccca cccagcacca ccagccgaac cugccccucc      420

ccgcccagca gcccuuccag ccgcagcccg ugcagcccca gccccaccag ccgaugcagc      480

cccagccgcc cgugcagccc augcagcccc ugcugcccca gccgccccuc ccgcccaugu      540

ucccccugcg gccccugccg cccauccucc ccgaccugca ccuggaggcg uggcccgcca      600

cggacaagac caagcaggag gaggucgacu gaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  2709
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt1)

<400>  2709
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccgcccca ccccggccac cccggguaca ucaacuucag cuacgagguc cugaccccgc      120

ucaaguggua ccaguccaug auccgcccgc ccuacagcuc cuacggcuac gagcccaugg      180

gcggguggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  2710
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt1)

<400>  2710
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccgcccca ccccggccac cccggguaca ucaacuucag cuacgagguc cugaccccgc      120

ucaaguggua ccaguccaug auccgcccgc cgcccauccu ccccgaccug caccuggagg      180

cguggcccgc cacggacaag accaagcagg aggaggucga cugaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  2711
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt1)

<400>  2711
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcccc gcggacccug guccuccugc ugagcggcgc gcucgcccug acccagacgu      120

gggccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc agcuacgagg      180

uccugacccc gcucaagugg uaccagucca ugauccgccc gcccuacagc uccuacggcu      240

acgagcccau gggcgggugg ugaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  2712
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt1)

<400>  2712
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcccc gcggacccug guccuccugc ugagcggcgc gcucgcccug acccagacgu      120

gggccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc agcuacgagg      180

uccugacccc gcucaagugg uaccagucca ugauccgccc gccgcccauc cuccccgacc      240

ugcaccugga ggcguggccc gccacggaca agaccaagca ggaggagguc gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  2713
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt1)

<400>  2713
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg ccgcguucag caugccccug ccgccccacc      120

ccggccaccc cggguacauc aacuucuccu acgaggugcu caccccgcug aagugguacc      180

agaacaugau ccgccacccc uacacgagcu acggcuacga gcccaugggc ggguggcugc      240

accaccagau cauccccguc gugucccagc agaccccgca gagccacgcc cuccagcccc      300

accaccacau ccccauggug cccgcccagc agccgggcau cccccagcag cccaugaugc      360

cccugccggg gcagcacucc augaccccca cccagcacca ccagcccaac cugccccucc      420

cggcccagca gcccuuccag ccccagcccg uccagccgca gccccaccag ccccugcagc      480

cccagagccc gaugcacccc auccagcccc ugcucccgca gccgccccug cccccgaugu      540

ucuccaugca gagccugcuc cccgaccugc cccuggaggc cuggcccgcg acggacaaga      600

ccaagcggga ggagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  2714
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt1)

<400>  2714
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccgcccca ccccggccac cccggguaca ucaacuucuc cuacgaggug cucaccccgc      120

ugaaguggua ccagaacaug auccgccacc ccuacacgag cuacggcuac gagcccaugg      180

gcggguggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  2715
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt1)

<400>  2715
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccgcccca ccccggccac cccggguaca ucaacuucuc cuacgaggug cucaccccgc      120

ugaaguggua ccagaacaug auccgccacc ccagccugcu ccccgaccug ccccuggagg      180

ccuggcccgc gacggacaag accaagcggg aggaggugga cugaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  2716
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt1)

<400>  2716
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcccc gcggacccug guccuccugc ugagcggcgc gcucgcccug acccagacgu      120

gggccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacgagg      180

ugcucacccc gcugaagugg uaccagaaca ugauccgcca ccccuacacg agcuacggcu      240

acgagcccau gggcgggugg ugaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  2717
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt1)

<400>  2717
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcccc gcggacccug guccuccugc ugagcggcgc gcucgcccug acccagacgu      120

gggccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacgagg      180

ugcucacccc gcugaagugg uaccagaaca ugauccgcca ccccagccug cuccccgacc      240

ugccccugga ggccuggccc gcgacggaca agaccaagcg ggaggaggug gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  2718
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt1)

<400>  2718
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg ccgcguucag caugccccug ccgccccacc      120

ccggccaccc cggguacauc aacuucuccu acauccgcca cccguacacc agcuacggcu      180

acgagcccau gggcgggugg cuccaccacc agaucauccc cguggucucc cagcagacgc      240

cccagagcca cgcccugcag ccgcaccacc acauccccau ggugcccgcc cagcagcccg      300

gcaucccgca gcagcccaug augccccugc ccgggcagca cuccaugacc ccgacccagc      360

accaccagcc caaccucccc cugcccgccc agcagccguu ccagccccag cccgugcagc      420

cccagccgca ccagccccug cagccccaga gccccaugca cccgauccag ccccuccugc      480

cccagccgcc ccugccgccc auguucucca ugcagagccu ccugcccgac cugccccucg      540

aggccuggcc cgcgaccgac aagacgaagc gggaggaggu cgacugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  2719
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt1)

<400>  2719
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggaucuu cuucgccugc cugcucgggg ccagccuggc gaugccccug ccgccccacc      120

ccggccaccc cggguacauc aacuucuccu acgaggugcu cacgccccug aagugguacc      180

agaacaugau ccgccacccc uacaccagcu acggcuacga gcccaugggc ggguggcugc      240

accaccagau cauccccguc gugucccagc agaccccgca gagccacgcc cuccagcccc      300

accaccacau ccccauggug cccgcccagc agccgggcau cccccagcag cccaugaugc      360

cccugccggg gcagcacucc augaccccca cccagcacca ccagcccaac cugccccucc      420

cggcccagca gcccuuccag ccccagcccg uccagccgca gccccaccag ccccugcagc      480

cccagagccc gaugcacccc auccagcccc ugcucccgca gccgccccug ccgcccaugu      540

ucuccaugca gagccugcuc cccgaccugc cccuggaggc cuggcccgcg acggacaaga      600

ccaagcggga ggagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  2720
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt1)

<400>  2720
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg ccgcguucag caugccccug ccgccccacc      120

ccggccaccc cggguacauc aacuucuccu acgaggugcu caccccgcug aagugguacc      180

agaacaugau ccgccacccc agccugcucc ccgaccugcc ccuggaggcc uggccggcca      240

cggacaagac caagcgggag gaggucgacu gaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  2721
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt1)

<400>  2721
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg ccgcguucag caugccccug ccgccccacc      120

ccggccaccc cggguacauc aacuucuccu acgaggaccu cuaccuggag gccauccgca      180

ucgaccggac cgccuucgug cugacgcccc ucaaguggua ccagaacaug auccgccacc      240

ccuacaccag cuacggcuac gagcccaugg gcggguggcu gcaccaccag aucauccccg      300

ucguguccca gcagaccccg cagagccacg cccugcagcc ccaccaccac auccccaugg      360

ugcccgccca gcagccgggc aucccccagc agcccaugau gccccucccg gggcagcacu      420

ccaugacccc cacgcagcac caccagccca accugccccu gccggcgcag cagcccuucc      480

agccccagcc cguccagccg cagccccacc agccccucca gccccagagc ccgaugcacc      540

ccauccagcc ccugcugccg cagccgcccc ugccgcccau guucuccaug cagagccucc      600

ugcccgaccu cccccuggag gccuggcccg ccaccgacaa gaccaagcgg gaggaggugg      660

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  2722
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt1)

<400>  2722
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg ccgcguucag caugccccug ccgccccacc      120

ccggccaccc cggguacauc aacuucuccu acgaggugcu caccccgcug aagugguacc      180

agaacaugau ccgccacccc acgccccaga gccacgcccu gcagccccac caccacaucc      240

cgaugguccc cgcccagcag cccggcaucc cccagcagcc gaugaugccc cuccccgggc      300

agcacuccau gacccccacc cagcaccacc agccgaaccu gccccugccc gcccagcagc      360

ccuuccagcc gcagcccgug cagccccagc cccaccagcc gcuccagccc cagagcccca      420

ugcaccccau ccagccgcug cugccccagc ccccgcuccc gcccauguuc uccaugcaga      480

gccugcugcc cgaccucccc cuggaggccu ggcccgcgac cgacaagacg aagcgggagg      540

agguggacug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  2723
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt1)

<400>  2723
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccgcccca ccccggccac cccggguaca ucaacuucag cuacgaggug cucaccccgc      120

ugaaguggua ccagaacaug auccgccacc ccuacaccuc cuacggcuac gagcccaugg      180

gcggguggcu gcaccaccag aucauccccg ucgugagcca gcagacgccg cagucccacg      240

cccuccagcc ccaccaccac auccccaugg ugcccgccca gcagcccggg aucccccagc      300

agcccaugau gccccugccg ggccagcaca gcaugacccc cacccagcac caccagccca      360

accugccccu cccggcgcag cagcccuucc agccccagcc cguccagccg cagccccacc      420

agccccugca gccccagucc ccgaugcacc ccauccagcc ccugcucccg cagccgcccc      480

ugccgcccau guucagcaug cagucccugc uccccgaccu gccccuggag gccuggcccg      540

ccaccgacaa gacgaagcgg gaggaggugg acugaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  2724
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt1)

<400>  2724
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gcguggcccg ccugccgcuc cugcuggggc uccugcugcu cccccggccc ggccgccccc      120

uggaccuggc cgacuacacc uacgaccucg ccgaggagga cgacagcgag ccgcugaacu      180

acaaggaccc cugcaaggcc gccgccuucc ugggggacau cgcccucgac gaggaggacc      240

ugcgggcguu ccagguccag caggccgugg accugcgccg gcacaccgcc cgcaagucca      300

gcaucaaggc cgcggugccc ggcaacacgu ccacccccag cugccagucc accaacgggc      360

agccgcagcg gggcgccugc ggccgcuggc gggggcgcag ccggucccgc cgggccgcca      420

ccagccgccc cgagcggguc uggcccgacg gcgugauccc cuucgugauc gggggcaacu      480

ucacgggguc ccagcgcgcc gucuuccggc aggcgaugcg ccacugggag aagcacacgu      540

gcgugaccuu ccucgagcgg accgacgagg acagcuacau cguguucacc uaccgcccgu      600

gcggcugcug cuccuacguc ggccggcgcg ggggcgggcc ccaggccauc agcaucggca      660

agaacugcga caaguucggc aucguggugc acgagcuggg gcacgucgug ggcuucuggc      720

acgagcacac ccgccccgac cgggaccgcc acguguccau cguccgggag aacauccagc      780

ccgggcagga guacaacuuc cugaagaugg agccgcagga gguggagagc cucggcgaga      840

ccuacgacuu cgacuccauc augcacuacg cccgcaacac cuucagccgg gggaucuucc      900

uggacacgau cgugcccaag uacgagguca acggcgugaa gccgcccauc ggccagcgca      960

cccggcuguc caagggggac aucgcccagg cccgcaagcu cuacaagugc cccgcgugcg     1020

gcgagacccu gcaggacagc accgggaacu ucuccagccc cgaguacccc aacggcuaca     1080

gcgcccacau gcacugcgug uggcggaucu ccgucacgcc cggggagaag aucauccuga     1140

acuucaccag ccucgaccug uaccgcuccc ggcugugcug guacgacuac guggaggugc     1200

gcgacggcuu cuggcggaag gccccgcucc gcggccgguu cugcgggagc aagcugcccg     1260

agcccaucgu cuccaccgac agccgccugu ggguggaguu ccgguccagc uccaacuggg     1320

ucggcaaggg guucuucgcc guguacgagg ccaucugcgg cggggacgug aagaaggacu     1380

acggccacau ccagagcccc aacuacccgg acgacuaccg ccccuccaag gucugcaucu     1440

ggcggaucca ggugagcgag ggcuuccacg uggggcucac cuuccagucc uucgagaucg     1500

agcgccacga cagcugcgcg uacgacuacc uggagguccg cgacggccac uccgagagcu     1560

ccacgcugau cgggcgguac ugcggcuacg agaagcccga cgacaucaag agcaccucca     1620

gccgccucug gcugaaguuc gugagcgacg gcuccaucaa caaggccggg uucgccguga     1680

acuucuucaa ggaggucgac gagugcagcc ggccgaaccg cggcgggugc gagcagcggu     1740

gccugaacac ccucggcucc uacaagugca gcugcgaccc cggguacgag cuggcccccg     1800

acaagcgccg gugcgaggcc gcgugcggcg gcuuccugac caagcucaac ggguccauca     1860

cgagccccgg cuggccgaag gaguacccgc ccaacaagaa cugcaucugg cagcuggugg     1920

cccccaccca guaccgcauc ucccugcagu ucgacuucuu cgagaccgag gggaacgacg     1980

ugugcaagua cgacuucguc gaggugcgga gcggccucac cgccgacucc aagcugcacg     2040

ggaaguucug cggcagcgag aagcccgagg ugaucacguc ccaguacaac aacaugcgcg     2100

ucgaguucaa gagcgacaac accgugucca agaagggcuu caaggcccac uucuucagcg     2160

acaaggacga gugcuccaag gacaacgggg gcugccagca ggacugcgug aacaccuucg     2220

ggagcuacga gugccagugc cgguccggcu ucguccugca cgacaacaag cacgacugca     2280

aggaggcggg gugcgaccac aaggugacca gcacgagcgg caccaucacc ucccccaacu     2340

ggcccgacaa guaccccagc aagaaggagu gcaccugggc caucuccagc acgccgggcc     2400

accgcgugaa gcucaccuuc auggagaugg acaucgaguc ccagcccgag ugcgccuacg     2460

accaccugga ggucuucgac gggcgggacg ccaaggcccc cgugcugggc cgcuucugcg     2520

ggagcaagaa gcccgagccg gugcucgcga ccggcucccg gauguuccug cgcuucuaca     2580

gcgacaacuc cguccagcgg aagggguucc aggccagcca cgccaccgag ugcggcggcc     2640

aggugcgcgc cgacgugaag accaaggacc uguacuccca cgcccaguuc ggggacaaca     2700

acuaccccgg cggggucgac ugcgaguggg ugaucguggc ggaggagggc uacggcgucg     2760

agcugguguu ccagacguuc gagguggagg aggagaccga cugcggguac gacuacaugg     2820

agcuguucga cggcuacgac agcaccgcgc cccggcucgg gcgcuacugc ggcuccgggc     2880

ccccggagga ggucuacagc gccggcgacu ccgugcuggu gaaguuccac agcgacgaca     2940

ccaucacgaa gaagggcuuc caccuccggu acaccuccac caaguuccag gacacccugc     3000

acagccgcaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  2725
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt1)

<400>  2725
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

ccggcacccg cugccugcuc gcccugcugc ucccccaggu ccugcucggg ggcgcggccg      120

ggcuggugcc ggagcugggc cggcgcaagu ucgccgccgc cagcuccggg cggcccagcu      180

cccagcccag cgacgaggug cuguccgagu ucgagcuccg ccugcugagc auguucggcc      240

ucaagcagcg gcccaccccg ucccgcgacg cggucgugcc gcccuacaug cuggaccugu      300

accggcgcca cagcggccag cccggguccc ccgcccccga ccaccggcuc gagcgcgccg      360

ccagccgggc gaacacggug cgcuccuucc accacgagga gagccuggag gagcugcccg      420

agaccuccgg caagaccacc cggcgcuucu ucuucaaccu cagcuccauc cccacggagg      480

aguucaucac cagcgccgag cugcaggucu uccgggagca gaugcaggac gcccugggga      540

acaacuccag cuuccaccac cgcaucaaca ucuacgagau caucaagccg gccaccgcca      600

acuccaaguu ccccgugacc cggcuccugg acacgcgccu ggugaaccag aacgcgagcc      660

ggugggagag cuucgacguc acccccgccg ugaugcgcug gaccgcccag ggccacgcca      720

accacggguu cguggucgag guggcccacc ucgaggagaa gcagggcgug uccaagcggc      780

acguccgcau cagccgcucc cugcaccagg acgagcacag cuggucccag auccggcccc      840

ugcucgugac cuucggccac gacgggaagg gccacccgcu gcacaagcgc gagaagcggc      900

aggcgaagca caagcagcgc aagcggcuca agagcuccug caagcgccac ccccuguacg      960

uggacuucag cgacgucggg uggaacgacu ggaucguggc cccgcccggc uaccacgccu     1020

ucuacugcca cggcgagugc cccuuccccc uggccgacca ccugaacucc acgaaccacg     1080

ccaucgugca gacccucguc aacagcguga acuccaagau ccccaaggcg ugcugcgugc     1140

ccaccgagcu gagcgccauc uccaugcugu accucgacga gaacgagaag gucgugcuga     1200

agaacuacca ggacaugguc guggaggggu gcggcugccg gugaggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  2726
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt1)

<400>  2726
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaucc       60

ccggcaaccg caugcugaug gugguccucc ugugccaggu gcugcucggg ggcgccagcc      120

acgccucccu gaucccggag accgggaaga agaagguggc ggagauccag ggccacgccg      180

ggggccggcg cagcggccag ucccacgagc ugcuccggga cuucgaggcc acccugcugc      240

agauguucgg gcuccgccgg cgcccccagc ccagcaaguc cgccgucauc cccgacuaca      300

ugcgggaccu guaccgccug cagagcggcg aggaggagga ggagcagauc cacuccacgg      360

ggcucgagua cccggagcgg cccgccagcc gcgcgaacac cgugcggucc uuccaccacg      420

aggagcaccu ggagaacauc cccggcacca gcgagaacuc cgccuuccgc uuccuguuca      480

accucagcuc cauccccgag aacgagguga ucagcuccgc cgagcugcgg cuguuccgcg      540

agcaggucga ccaggggccg gacugggagc ggggcuucca ccgcaucaac aucuacgagg      600

ugaugaagcc gcccgccgag gugguccccg gccaccucau cacccggcug cuggacacgc      660

gccucgugca ccacaacgug acccgguggg agaccuucga cgucagcccc gcggugcugc      720

gcuggacccg ggagaagcag cccaacuacg ggcuggccau cgaggugacg caccuccacc      780

agacccgcac ccaccagggc cagcacgucc gcaucucccg gagccugccc cagggguccg      840

gcaacugggc ccagcugcgc ccccuccugg ugaccuucgg ccacgacggg cggggccacg      900

cccugacgcg ccggcgccgg gccaagcgca gcccgaagca ccacagccag cgggcgcgca      960

agaagaacaa gaacugccgg cgccacuccc ucuacgugga cuucagcgac gucgggugga     1020

acgacuggau cguggccccg cccggcuacc aggccuucua cugccacggg gacugccccu     1080

ucccccuggc cgaccaccug aacuccacca accacgccau cgugcagacc cucgucaaca     1140

gcgugaacuc cagcaucccc aaggcgugcu gcgugcccac cgagcugucc gccaucagca     1200

ugcuguaccu cgacgaguac gacaaggucg ugcugaagaa cuaccaggag auggucgugg     1260

agggcugcgg cugccgguga ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  2727
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt1)

<400>  2727
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gccuggggcg ccgggcccag uggcucugcu gguggugggg ccugcugugc agcugcugcg      120

ggccgccgcc ccuccggccg ccccugcccg ccgcggccgc cgccgccgcg ggcgggcagc      180

ugcucggcga cggcgggucc cccggccgga ccgagcagcc cccgcccagc ccccagucca      240

gcuccggguu ccuguaccgc cggcugaaga cccaggagaa gcgcgagaug cagaaggaga      300

uccucagcgu gcugggccug ccccaccggc cccgcccccu ccacgggcug cagcagcccc      360

agcccccggc ccugcggcag caggaggagc agcagcagca gcagcagcuc ccccgcggcg      420

agcccccgcc cggccggcug aaguccgcgc cccuguucau gcucgaccug uacaacgccc      480

ugagcgccga caacgacgag gacggggccu ccgagggcga gcgccagcag agcuggcccc      540

acgaggccgc cuccagcucc cagcggcgcc agcccccgcc cggggccgcg cacccccuca      600

accgcaagag ccugcuggcc cccggcuccg gcagcggggg cgccuccccg cucacgagcg      660

cccaggacuc cgccuuccug aacgacgcgg acauggucau gagcuucgug aaccuggugg      720

aguacgacaa ggaguucagc ccccgccagc ggcaccacaa ggaguucaag uucaaccucu      780

cccagauccc cgagggggag gucgugaccg ccgccgaguu ccgcaucuac aaggacugcg      840

ugaugggcag cuucaagaac cagaccuucc ugaucuccau cuaccagguc cugcaggagc      900

accagcaccg ggacagcgac cucuuccugc uggacacccg cguggugugg gccuccgagg      960

agggguggcu cgaguucgac aucacggcca ccagcaaccu gugggucgug accccgcagc     1020

acaacauggg ccugcagcuc uccgugguca cccgggacgg cgugcacgug cacccccgcg     1080

cggccgggcu ggucggccgc gacgggcccu acgacaagca gcccuucaug guggccuucu     1140

ucaaggugag cgagguccac gugcggacga cccgcuccgc cagcucccgg cgccggcagc     1200

agagccgcaa ccgguccacc cagagccagg acguggcccg cgucuccagc gcguccgacu     1260

acaacagcuc cgagcugaag accgccugcc ggaagcacga gcucuacgug agcuuccagg     1320

accugggcug gcaggacugg aucaucgccc cgaaggggua cgccgcgaac uacugcgacg     1380

gcgagugcag cuucccccug aacgcccaca ugaacgccac gaaccacgcc aucgugcaga     1440

cccucgucca ccugaugaac cccgaguacg ugcccaagcc gugcugcgcc cccaccaagc     1500

ugaacgcgau cuccguccuc uacuucgacg acaacagcaa cgugauccug aagaaguacc     1560

gcaacauggu gguccgggcc ugcggcugcc acugaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  2728
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt1)

<400>  2728
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

ugcgcagccu gcgggccgcc gcgccccacu ccuucgucgc ccucugggcc ccgcuguucc      120

ugcuccgcag cgcccuggcc gacuucuccc uggacaacga ggugcacagc uccuucaucc      180

accggcgccu ccggagccag gagcgccggg agaugcagcg cgagauccug uccauccugg      240

gccuccccca ccggccccgc ccccaccucc aggggaagca caacagcgcg ccgauguuca      300

ugcuggaccu guacaacgcc auggccgugg aggagggcgg gggccccggg ggccagggcu      360

ucuccuaccc cuacaaggcc gucuucagca cccaggggcc cccgcuggcg ucccugcagg      420

acagccacuu ccucaccgac gccgacaugg ugauguccuu cgugaaccug gucgagcacg      480

acaaggaguu cuuccacccc cgguaccacc accgcgaguu ccgguucgac cugagcaaga      540

uccccgaggg cgaggccgug acggccgccg aguuccgcau cuacaaggac uacauccggg      600

agcgcuucga caacgagacc uuccggaucu ccguguacca gguccuccag gagcaccugg      660

ggcgcgagag cgaccuguuc cuccuggacu cccggacccu gugggcgagc gaggagggcu      720

ggcucguguu cgacaucacc gccacgucca accacugggu ggucaacccc cgccacaacc      780

uggggcugca gcucagcgug gagacccugg acggccagag caucaacccg aagcuggccg      840

gccucaucgg gcggcacggc ccccagaaca agcagcccuu caugguggcc uucuucaagg      900

ccaccgaggu ccacuuccgc uccauccgca gcaccggguc caagcagcgg agccagaacc      960

gcuccaagac gcccaagaac caggaggcgc ugcggauggc caacguggcc gagaacagcu     1020

ccagcgacca gcgccaggcc ugcaagaagc acgagcugua cguguccuuc cgggaccucg     1080

gcuggcagga cuggaucauc gccccggagg gcuacgcggc cuacuacugc gagggggagu     1140

gcgccuuccc ccugaacagc uacaugaacg ccaccaacca cgccaucguc cagacccugg     1200

ugcacuucau caaccccgag accgugccca agccgugcug cgcgcccacg cagcucaacg     1260

ccaucuccgu ccuguacuuc gacgacagcu ccaacgugau ccugaagaag uaccgcaaca     1320

uggugguccg ggccugcggc ugccacugag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  2729
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt1)

<400>  2729
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagg       60

ccagcgccgc gcugcucugc cugcugcuca ccgccgccgc cuucagcccc cagggccugg      120

cccagccggu ggggaucaac accuccacga ccugcugcua ccgcuucauc aacaagaaga      180

uccccaagca gcggcuggag uccuaccgcc ggaccaccag cucccacugc ccccgcgagg      240

cggucaucuu caagacgaag cucgacaagg agaucugcgc cgaccccacc cagaaguggg      300

ugcaggacuu caugaagcac cuggacaaga agacccagac cccgaagcug ugaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  2730
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt1)

<400>  2730
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugc       60

ucacccugau cauccugcuc cccgugguca gcaaguucuc cuucgugagc cuguccgcgc      120

cccagcacug gagcugcccc gagggcaccc uggccgggaa cggcaacucc acgugcgugg      180

ggcccgcccc cuuccucauc uucagccacg gcaacuccau cuuccgcauc gacaccgagg      240

ggaccaacua cgagcagcug gucguggacg ccggcgugag cgucaucaug gacuuccacu      300

acaacgagaa gcggaucuac uggguggacc uggagcgcca gcuccugcag cggguguucc      360

ugaacggcuc ccgccaggag cgggucugca acaucgagaa gaacgugagc gggauggcca      420

ucaacuggau caacgaggag gugaucuggu ccaaccagca ggagggcauc aucaccguca      480

cggacaugaa ggggaacaac agccacaucc uccuguccgc ccugaaguac ccggccaacg      540

uggcggugga ccccgucgag cgcuucaucu ucuggagcuc cgagguggcc ggcagccucu      600

accgggccga ccuggacggg gugggcguca aggcccugcu cgagaccucc gagaagauca      660

ccgcggugag ccuggacgug cuggacaagc gccucuucug gauccaguac aaccgggagg      720

gcuccaacag ccugaucugc agcugcgacu acgacggggg cuccguccac aucagcaagc      780

accccaccca gcacaaccug uucgccaugu cccucuucgg ggaccgcauc uucuacagca      840

cguggaagau gaagaccauc uggaucgcca acaagcacac cggcaaggac auggugcgga      900

ucaaccugca cuccagcuuc gugccccugg gcgagcucaa ggucgugcac ccgcuggccc      960

agcccaaggc cgaggacgac accugggagc ccgagcagaa gcugugcaag cuccgcaagg     1020

ggaacugcuc cagcacgguc ugcggccagg accugcaguc ccaccugugc augugcgcgg     1080

agggguacgc ccucagccgg gaccgcaagu acugcgagga cgugaacgag ugcgccuucu     1140

ggaaccacgg cugcacccug gggugcaaga acacccccgg cuccuacuac ugcacgugcc     1200

cggugggcuu cguccugcuc cccgacggga agcggugcca ccagcuggug agcugccccc     1260

gcaacguguc cgagugcagc cacgacugcg uccugaccuc cgagggcccc cucugcuucu     1320

gcccggaggg gagcgugcug gagcgggacg gcaagaccug cuccgggugc agcucccccg     1380

acaacggcgg cugcagccag cugugcgugc cccucagccc cgucuccugg gagugcgacu     1440

gcuucccggg guacgaccug cagcuggacg agaaguccug cgccgccagc ggcccccagc     1500

ccuuccuccu guucgcgaac agccaggaca uccgccacau gcacuucgac gggaccgacu     1560

acggcacccu gcucucccag cagaugggga ugguguacgc ccuggaccac gaccccgugg     1620

agaacaagau cuacuucgcc cacacggccc ugaaguggau cgagcgggcc aacauggacg     1680

gcagccagcg cgagcggcug aucgaggagg gcgucgacgu gccggagggg cucgcggugg     1740

acuggaucgg ccgccgcuuc uacuggaccg accgggggaa gucccugauc ggccgcagcg     1800

accugaacgg caagcggucc aagaucauca ccaaggagaa caucagccag ccccgcggga     1860

ucgccgucca ccccauggcc aagcgccucu ucuggaccga cacgggcauc aacccccgga     1920

ucgaguccag cucccugcag gggcugggcc ggcucgugau cgccagcucc gaccugaucu     1980

ggccgagcgg gaucaccauc gacuuccuga ccgacaagcu cuacuggugc gacgccaagc     2040

aguccgugau cgagauggcg aaccuggacg gcagcaagcg ccggcgccug acccagaacg     2100

acgucggcca ccccuucgcc guggccgugu ucgaggacua cgucugguuc agcgacuggg     2160

ccaugcccuc cgugaugcgg gugaacaagc gcacggggaa ggaccggguc cgccuccagg     2220

gcagcaugcu gaagccgucc agccuggugg ugguccaccc ccucgcgaag cccggggccg     2280

accccugccu guaccagaac ggcgggugcg agcacaucug caagaagcgg cugggcaccg     2340

ccuggugcuc cugccgcgag ggcuucauga aggccagcga cgggaagacc ugccucgccc     2400

uggacggcca ccagcugcuc gccgggggcg agguggaccu gaagaaccag gugaccccgc     2460

uggacauccu cuccaagacg cgggucagcg aggacaacau caccgagucc cagcacaugc     2520

ugguggccga gaucauggug agcgaccagg acgacugcgc ccccgucggg ugcuccaugu     2580

acgcccgcug caucagcgag ggcgaggacg cgaccugcca gugccugaag ggcuucgcgg     2640

gggacggcaa gcucugcucc gacaucgacg agugcgagau gggggugccc gugugcccgc     2700

cggccagcuc caagugcauc aacaccgagg gcggguacgu cugccggugc agcgagggcu     2760

accagggcga cgggauccac ugccuggaca ucgacgagug ccagcugggc gagcacuccu     2820

gcggggagaa cgccagcugc acgaacaccg agggcggcua cacgugcaug ugcgccgggc     2880

gccucuccga gcccggccug aucugccccg acagcacgcc cccgccccac cuccgcgagg     2940

acgaccacca cuacagcgug cggaacuccg acagcgagug cccccugucc cacgacgggu     3000

acugccugca cgacggcgug ugcauguaca ucgaggcccu ggacaaguac gcgugcaacu     3060

gcgucguggg guacaucggc gagcgcugcc aguaccggga ccucaagugg ugggagcugc     3120

gccacgccgg ccacgggcag cagcagaagg ugaucgucgu ggccgugugc gucguggugc     3180

uggucaugcu ccugcugcuc agccuguggg gcgcccacua cuaccggacc cagaagcugc     3240

ucuccaagaa ccccaagaac ccguacgagg agagcucccg cgacgugcgg agccgccggc     3300

ccgcggacac cgaggacggg auguccagcu gcccccagcc cugguucgug gucaucaagg     3360

agcaccagga ccugaagaac ggcgggcagc cgguggccgg cgaggacggc caggccgccg     3420

acggguccau gcagcccacc agcuggcgcc aggagcccca gcugugcggc auggggaccg     3480

agcagggcug cuggaucccc gucuccagcg acaagggguc cugcccccag gugauggagc     3540

ggagcuucca caugcccucc uacggcaccc agacccucga gggcggggug gagaagcccc     3600

acagccugcu guccgccaac ccgcucuggc agcagcgcgc gcuggacccg ccccaccaga     3660

uggagcugac ccagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  2731
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt1)

<400>  2731
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

ccggccgccg gauggagaug cugugcgccg ggcgcgugcc cgcgcuccug cugugccucg      120

gcuuccaccu ccugcaggcc guccugagca ccacggugau cccguccugc auccccgggg      180

agagcuccga caacugcacc gcccuggugc agaccgagga caacccccgg gucgcccagg      240

ugagcaucac caagugcucc agcgacauga acggcuacug ccugcacggg cagugcaucu      300

accucgugga caugucccag aacuacugcc gcugcgaggu cggcuacacg ggcgugcggu      360

gcgagcacuu cuuccugacc gugcaccagc cccugagcaa ggaguacguc gcccucaccg      420

ugauccugau cauccuguuc cucaucaccg uggucggguc cacguacuac uucugccgcu      480

gguaccggaa ccgcaagagc aaggagccga agaaggagua cgagcgggug accuccggcg      540

accccgagcu gccccaggug ugaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  2732
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt1)

<400>  2732
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

agggcgagau caccaccuuc acggcccuga ccgagaaguu caaccugccc ccggggaacu      120

acaagaagcc caagcuccug uacugcagca acggcgggca cuuccuccgc auccugcccg      180

acggcaccgu ggacgggacc cgggaccgcu ccgaccagca cauccagcug cagcucagcg      240

cggaguccgu cggcgaggug uacaucaaga gcacggagac cggccaguac cuggccaugg      300

acaccgacgg gcugcucuac ggcucccaga cccccaacga ggagugccug uuccuggagc      360

ggcucgagga gaaccacuac aacacguaca ucagcaagaa gcacgccgag aagaacuggu      420

ucguggggcu gaagaagaac ggcuccugca agcgcgggcc gcggacccac uacggccaga      480

aggccauccu guuccucccc cugcccguca gcuccgacug aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  2733
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt1)

<400>  2733
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

gcgucggggg cggggacgug gaggacguga ccccgcgccc gggcgggugc cagaucagcg      120

gccggggcgc ccgcgggugc aacggcaucc ccggggccgc ggccugggag gccgcccugc      180

cccggcgccg gccccgccgg cacccguccg ucaacccccg cagccgggcc gcgggcagcc      240

cccgcacccg ggggcgccgg acggaggagc gccccuccgg cucccggcuc ggcgaccgcg      300

ggcggggccg cgcccugccc gggggccggc ugggcgggcg cggccggggg cgcgcccccg      360

agcgcguggg cgggcggggc cgcggccggg ggaccgccgc gccccgcgcc gcccccgccg      420

cccggggcag ccgcccgggg cccgcgggca ccauggccgc cggguccauc accacgcucc      480

ccgcccugcc cgaggacggc ggcagcgggg ccuucccgcc cggccacuuc aaggacccca      540

agcggcugua cugcaagaac gggggcuucu uccuccgcau ccaccccgac gggcgggugg      600

acggcguccg cgagaagucc gacccgcaca ucaagcugca gcugcaggcg gaggagcggg      660

gcguggugag caucaagggg gucugcgcca accgcuaccu cgccaugaag gaggacggcc      720

ggcugcuggc cuccaagugc gugaccgacg agugcuucuu cuucgagcgc cucgagagca      780

acaacuacaa caccuaccgg ucccgcaagu acaccagcug guacguggcc cugaagcgga      840

cggggcagua caagcugggc uccaagaccg gccccgggca gaaggcgauc cucuuccugc      900

ccaugagcgc caaguccuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  2734
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt1)

<400>  2734
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aguggauccu gaccuggauc cuccccaccc ugcuguaccg cagcugcuuc cacaucaucu      120

gccucguggg cacgaucucc cuggccugca acgacaugac cccggagcag auggccacca      180

acgucaacug cagcuccccc gagcggcaca cccgcagcua cgacuacaug gagggcgggg      240

acauccgggu gcgccggcug uucugccgca cgcaguggua ccuccggauc gacaagcgcg      300

ggaaggugaa gggcacccag gagaugaaga acaacuacaa caucauggag auccggaccg      360

ucgcgguggg gaucguggcc aucaagggcg ucgaguccga guucuaccug gccaugaaca      420

aggagggcaa gcuguacgcc aagaaggagu gcaacgagga cugcaacuuc aaggagcuca      480

uccuggagaa ccacuacaac accuacgcca gcgcgaagug gacgcacaac gggggcgaga      540

uguucguggc ccugaaccag aaggggaucc ccgugcgcgg caagaagacc aagaaggagc      600

agaagaccgc ccacuuccuc cccauggcca ucaccugagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  2735
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt1)

<400>  2735
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ugcuccccag cgugguccug aagcuguucc ucgccgccgu gcuguccgcg cuggugaccg      120

gcgagagccu cgagcggcug cggcgcgggc uggccgccgg caccuccaac ccggacccgc      180

ccacggucag caccgaccag cuccugcccc ucgggggcgg gcgggaccgc aaggugcggg      240

accugcagga ggccgaccug gaccugcucc gcgugacccu guccagcaag ccccaggccc      300

uggcgacccc caacaaggag gagcacggca agcggaagaa gaagggcaag gggcucggca      360

agaagcgcga ccccugccug cggaaguaca aggacuucug cauccacggg gagugcaagu      420

acgucaagga gcugcgcgcc cccuccugca ucugccaccc gggcuaccac ggggagcggu      480

gccacggccu cagccugccc guggagaacc gccuguacac guacgaccac accaccaucc      540

ucgccguggu cgccguggug cuguccagcg ucugccugcu cgugaucgug ggccugcuga      600

uguuccggua ccaccgccgc gggggcuacg acgucgagaa cgaggagaag gugaagcucg      660

ggaugaccaa cucccacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  2736
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt1)

<400>  2736
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ugaccaagcu gcuccccgcc cugcugcucc agcacguccu gcugcaccuc cugcugcucc      120

cgaucgccau ccccuacgcg gagggccagc gcaagcggcg caacaccauc cacgaguuca      180

agaaguccgc caagacgacc cugaucaaga ucgaccccgc ccugaagauc aagaccaaga      240

aggugaacac cgccgaccag ugcgccaacc ggugcacgcg caacaagggg cuccccuuca      300

cgugcaaggc guucguguuc gacaaggccc ggaagcagug ccugugguuc ccguucaaca      360

gcaugagcuc cggcgucaag aaggaguucg ggcacgaguu cgaccuguac gagaacaagg      420

acuacauccg caacugcauc aucggcaagg ggcggagcua caagggcacc guguccauca      480

ccaagagcgg caucaagugc cagcccuggu ccagcaugau cccccacgag cacuccuucc      540

uccccagcuc cuaccgcggg aaggaccugc aggagaacua cugccggaac ccgcgcggcg      600

aggagggcgg gcccuggugc uucaccagca accccgaggu gcgguacgag gucugcgaca      660

ucccccagug cuccgaggug gagugcauga ccugcaacgg ggagagcuac cgcggccuga      720

uggaccacac cgaguccggc aagaucugcc agcgguggga ccaccagacc ccgcaccgcc      780

acaaguuccu ccccgagcgg uaccccgaca agggguucga cgacaacuac ugccgcaacc      840

ccgacggcca gccgcggccc uggugcuaca cgcuggaccc ccacacccgc ugggaguacu      900

gcgccaucaa gaccugcgcc gacaacacca ugaacgacac ggacgugccc cuggagacca      960

ccgagugcau ccaggggcag ggcgagggcu accgggggac cgucaacacg aucuggaacg     1020

gcaucccgug ccagcgcugg gacagccagu acccccacga gcacgacaug acccccgaga     1080

acuucaagug caaggaccuc cgggagaacu acugccgcaa ccccgacggg uccgagagcc     1140

cguggugcuu caccaccgac cccaacaucc gcgugggcua cugcucccag auccccaacu     1200

gcgacaugag ccacgggcag gacugcuacc ggggcaacgg caagaacuac auggggaacc     1260

ugagccagac gcgcuccggc cugaccugca gcauguggga caagaacaug gaggaccucc     1320

accggcacau cuucugggag cccgacgcgu ccaagcugaa cgagaacuac ugccgcaacc     1380

cggacgacga cgcccacggg cccuggugcu acaccggcaa cccccugauc ccgugggacu     1440

acugccccau cagccggugc gagggggaca ccacgcccac caucgugaac cucgaccacc     1500

ccgucaucuc cugcgccaag accaagcagc ugcgcguggu gaacggcauc ccgacccgga     1560

cgaacaucgg cuggaugguc agccugcgcu accggaacaa gcacaucugc gggggcuccc     1620

ucaucaagga gagcugggug cugaccgccc gccagugcuu ccccucccgg gaccugaagg     1680

acuacgaggc cuggcucggg auccacgacg ugcacggccg cggggacgag aagugcaagc     1740

agguccugaa cgugagccag cugguguacg gccccgaggg cuccgaccuc guccugauga     1800

agcuggcgcg gcccgccgug cucgacgacu ucgugagcac caucgaccug ccgaacuacg     1860

ggugcaccau ccccgagaag acguccugca gcgucuacgg cuggggguac accggccuga     1920

ucaacuacga cggccuccug cgcguggccc accuguacau cauggggaac gagaagugcu     1980

cccagcacca ccggggcaag gucacccuca acgagagcga gaucugcgcc ggggccgaga     2040

agaucggcuc cgggcccugc gagggcgacu acggcgggcc ccuggugugc gagcagcaca     2100

agaugcgcau ggugcugggc gucaucgugc cggggcgggg cugcgcgauc cccaaccgcc     2160

ccgggaucuu cgugcggguc gccuacuacg ccaaguggau ccacaagauc auccucaccu     2220

acaaggugcc ccagagcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  2737
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt1)

<400>  2737
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aggccgcggc caucggcauc gaccugggga ccaccuacag cugcgugggc guguuccagc      120

acgggaaggu ggagaucauc gccaacgacc agggcaaccg cacgaccccc uccuacgugg      180

ccuucaccga caccgagcgg cucaucgggg acgccgcgaa gaaccagguc gcccugaacc      240

cgcagaacac gguguucgac gccaagcgcc ugaucggccg gaaguucggc gaccccgugg      300

uccagagcga caugaagcac uggcccuucc aggugaucaa cgacggggac aagcccaagg      360

ugcaggucuc cuacaagggc gagaccaagg ccuucuaccc ggaggagauc agcuccaugg      420

ugcucaccaa gaugaaggag aucgcggagg ccuaccuggg guaccccgug accaacgccg      480

ucaucacggu gcccgccuac uucaacgaca gccagcgcca ggccaccaag gacgcgggcg      540

ugaucgccgg gcugaacguc cuccggauca ucaacgagcc caccgccgcc gccaucgcgu      600

acggccugga ccgcaccggc aagggggagc ggaacgugcu gaucuucgac cucggcgggg      660

gcacguucga cguguccauc cugaccaucg acgacggcau cuucgagguc aaggccaccg      720

ccggggacac ccaccugggc ggggaggacu ucgacaaccg ccucgugaac cacuucgugg      780

aggaguucaa gcggaagcac aagaaggaca ucagccagaa caagcgcgcc guccggcgcc      840

ugcggacggc cugcgagcgc gcgaagcgga cccuguccag cuccacccag gccagccucg      900

agaucgacuc ccuguucgag ggcaucgacu ucuacaccag caucacgcgc gcccgguucg      960

aggagcugug cuccgaccuc uuccgcagca cccuggagcc gguggagaag gcccugcggg     1020

acgccaagcu cgacaaggcg cagauccacg accuggugcu ggucgggggc uccacccgca     1080

uccccaaggu gcagaagcuc cugcaggacu ucuucaacgg ccgggaccug aacaagagca     1140

ucaaccccga cgaggccguc gccuacgggg ccgcggugca ggccgccauc cucaugggcg     1200

acaaguccga gaacgugcag gaccugcugc uccuggacgu cgcgccccug agccucgggc     1260

uggagaccgc cggcggggug augacggccc ugaucaagcg caacagcacc aucccgacca     1320

agcagaccca gaucuucacg accuacuccg acaaccagcc cggcgugcuc auccaggucu     1380

acgagggcga gcgcgccaug accaaggaca acaaccugcu ggggcgguuc gagcucagcg     1440

gcaucccgcc cgcgccccgc ggggugcccc agaucgaggu gaccuucgac aucgacgcca     1500

acggcauccu gaacgucacg gccaccgaca aguccaccgg gaaggccaac aagaucacca     1560

ucacgaacga caagggccgg cugagcaagg aggagaucga gcgcauggug caggaggccg     1620

agaaguacaa ggccgaggac gaggugcagc gggagcgcgu cuccgccaag aacgcccucg     1680

agagcuacgc guucaacaug aaguccgccg uggaggacga gggccugaag gggaagauca     1740

gcgaggccga caagaagaag gugcuggaca agugccagga ggucaucucc uggcucgacg     1800

ccaacacccu ggcggagaag gacgaguucg agcacaagcg gaaggagcug gagcaggucu     1860

gcaaccccau caucagcggc cucuaccagg gggccggcgg ccccgggccg ggcggguucg     1920

gcgcccaggg gcccaagggc ggcuccggga gcggccccac caucgaggag guggacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  2738
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt1)

<400>  2738
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aggccgcggc caucggcauc gaccugggga ccaccuacag cugcgugggc guguuccagc      120

acgggaaggu ggagaucauc gccaacgacc agggcaaccg cacgaccccc uccuacgugg      180

ccuucaccga caccgagcgg cucaucgggg acgccgcgaa gaaccagguc gcccugaacc      240

cgcagaacac gguguucgac gccaagcgcc ugaucggccg gaaguucggc gaccccgugg      300

uccagagcga caugaagcac uggcccuucc aggugaucaa cgacggggac aagcccaagg      360

ugcaggucuc cuacaagggc gagaccaagg ccuucuaccc ggaggagauc agcuccaugg      420

ugcucaccaa gaugaaggag aucgcggagg ccuaccuggg guaccccgug accaacgccg      480

ucaucacggu gcccgccuac uucaacgaca gccagcgcca ggccaccaag gacgcgggcg      540

ugaucgccgg gcugaacguc cuccggauca ucaacgagcc caccgccgcc gccaucgcgu      600

acggccugga ccgcaccggc aagggggagc ggaacgugcu gaucuucgac cucggcgggg      660

gcacguucga cguguccauc cugaccaucg acgacggcau cuucgagguc aaggccaccg      720

ccggggacac ccaccugggc ggggaggacu ucgacaaccg ccucgugaac cacuucgugg      780

aggaguucaa gcggaagcac aagaaggaca ucagccagaa caagcgcgcc guccggcgcc      840

ugcggacggc cugcgagcgc gcgaagcgga cccuguccag cuccacccag gccagccucg      900

agaucgacuc ccuguucgag ggcaucgacu ucuacaccag caucacgcgc gcccgguucg      960

aggagcugug cuccgaccuc uuccgcagca cccuggagcc gguggagaag gcccugcggg     1020

acgccaagcu cgacaaggcg cagauccacg accuggugcu ggucgggggc uccacccgca     1080

uccccaaggu gcagaagcuc cugcaggacu ucuucaacgg ccgggaccug aacaagagca     1140

ucaaccccga cgaggccguc gccuacgggg ccgcggugca ggccgccauc cucaugggcg     1200

acaaguccga gaacgugcag gaccugcugc uccuggacgu cgcgccccug agccucgggc     1260

uggagaccgc cggcggggug augacggccc ugaucaagcg caacagcacc aucccgacca     1320

agcagaccca gaucuucacg accuacuccg acaaccagcc cggcgugcuc auccaggucu     1380

acgagggcga gcgcgccaug accaaggaca acaaccugcu ggggcgguuc gagcucagcg     1440

gcaucccgcc cgcgccccgc ggggugcccc agaucgaggu gaccuucgac aucgacgcca     1500

acggcauccu gaacgucacg gccaccgaca aguccaccgg gaaggccaac aagaucacca     1560

ucacgaacga caagggccgg cugagcaagg aggagaucga gcgcauggug caggaggccg     1620

agaaguacaa ggccgaggac gaggugcagc gggagcgcgu cuccgccaag aacgcccucg     1680

agagcuacgc guucaacaug aaguccgccg uggaggacga gggccugaag gggaagauca     1740

gcgaggccga caagaagaag gugcuggaca agugccagga ggucaucucc uggcucgacg     1800

ccaacacccu ggcggagaag gacgaguucg agcacaagcg gaaggagcug gagcaggucu     1860

gcaaccccau caucagcggc cucuaccagg gggccggcgg ccccgggccg ggcggguucg     1920

gcgcccaggg gcccaagggc ggcuccggga gcggccccac caucgaggag guggacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  2739
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt1)

<400>  2739
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

ccgccaaggg caucgcgauc gggaucgacc ugggcaccac guacagcugc gugggggucu      120

uccagcacgg caagguggag aucaucgcca acgaccaggg gaaccgcacc acccccuccu      180

acguggccuu caccgacacg gagcggcuca ucggcgacgc cgccaagaac caggucgcga      240

ugaacccgca gaacaccgug uucgacgcca agcgccugau cggccggaag uucaacgacc      300

ccguggucca ggccgacaug aagcuguggc ccuuccaggu gaucaacgag ggcgggaagc      360

ccaaggugcu cgucagcuac aagggggaga acaaggccuu cuacccggag gagaucucca      420

gcauggugcu gaccaagcug aaggagaccg cggaggccuu ccucggccac cccgugacga      480

acgccgucau caccgugccc gccuacuuca acgacuccca gcgccaggcc accaaggacg      540

cgggggugau cgccggccug aacguccugc ggaucaucaa cgagcccacc gccgccgcca      600

ucgcguacgg ccucgacaag ggcgggcagg gggagcgcca cgugcugauc uucgaccugg      660

gcggcgggac guucgacgug agcauccuca ccaucgacga cggcaucuuc gaggucaagg      720

ccaccgccgg ggacacccac cugggcgggg aggacuucga caaccggcug gugucccacu      780

ucguggagga guucaagcgc aagcacaaga aggacaucag ccagaacaag cgggccgucc      840

gccggcuccg cacggccugc gagcgggcga agcgcacccu guccagcucc acccaggcca      900

accuggagau cgacagccuc uacgagggca ucgacuucua caccuccauc acgcgggccc      960

gcuucgagga gcugugcgcc gaccuguucc ggggcacccu cgagccggug gagaaggccc     1020

ugcgcgacgc gaagauggac aaggccaaga uccacgacau cgugcugguc gggggcagca     1080

cccggauccc caaggugcag cgccuccugc aggacuacuu caacgggcgg gaccugaaca     1140

aguccaucaa ccccgacgag gccgucgccu acggcgcggc cgugcaggcc gccauccuca     1200

ugggggacaa gagcgagaag gugcaggacc ugcugcuccu ggacgucgcg ccccuguccc     1260

ucggccugga gaccgccggc ggggugauga cggcccugau caagcgcaac agcaccaucc     1320

cgaccaagca gacccagauc uucacgaccu acuccgacaa ccagcccggc gugcucaucc     1380

aggucuacga gggggagcgc gccaugacca aggacaacaa ccugcugggc cgguucgacc     1440

ucaccgggau cccgcccgcg ccccgcggcg ugccccagau cgaggugacg uucgacaucg     1500

acgccaacgg cauccugaac gucaccgcca ccgacaagag caccgggaag gugaacaaga     1560

ucacgaucac caacgacaag ggccggcuga gcaaggagga gaucgagcgc auggugcucg     1620

acgccgagaa guacaaggcc gaggacgagg uccagcggga gaagaucgcc gccaagaacg     1680

cgcuggaguc cuacgccuuc aacaugaagu ccguggugag cgacgagggg cugaagggca     1740

agaucagcga guccgacaag aacaagaucc ucgacaagug caacgagcug cugagcuggc     1800

ucgaggucaa ccagcuggcc gagaaggacg aguucgacca caagcgcaag gagcuggagc     1860

agaugugcaa ccccaucauc accaagcugu accagggcgg gugcaccggc cccgccugcg     1920

ggaccggcua cgugccgggg cggcccgcga cgggccccac caucgaggag guggacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  2740
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt1)

<400>  2740
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

cccgcggccc cgccaucggg aucgaccugg gcaccaccua cuccugcgug ggggucuucc      120

agcacggcaa gguggagauc aucgcgaacg accaggggaa ccggacgacc ccgagcuacg      180

uggccuucac cgacaccgag cgccucaucg gcgacgccgc caagaaccag gucgccauga      240

accccacgaa caccaucuuc gacgcgaagc ggcugaucgg ccgcaaguuc gaggacgcca      300

ccgugcaguc cgacaugaag cacuggcccu uccggguggu cagcgagggc gggaagccca      360

agguccaggu ggaguacaag ggggagacca agacguucuu cccggaggag aucuccagca      420

uggugcugac caagaugaag gagaucgccg aggccuaccu cggcgggaag gugcacuccg      480

cggugaucac cguccccgcc uacuucaacg acagccagcg ccaggccacc aaggacgccg      540

gcacgaucac cggccugaac gugcugcgga ucaucaacga gcccaccgcc gcggccaucg      600

ccuacgggcu cgacaagaag ggcugcgccg ggggcgagaa gaacgugcug aucuucgacc      660

ugggcggggg caccuucgac gucuccaucc ucacgaucga ggacgggauc uucgagguca      720

agagcaccgc cggcgacacc caccucgggg gcgaggacuu cgacaaccgc augguguccc      780

accuggcgga ggaguucaag cggaagcaca agaaggacau cggccccaac aagcgcgccg      840

ugcggcgccu gcggaccgcc ugcgagcgcg ccaagcggac gcugagcucc agcacccagg      900

ccuccaucga gaucgacagc cuguacgagg ggguggacuu cuacaccucc aucacccgcg      960

cgcgguucga ggagcucaac gccgaccugu uccgcggcac gcuggagccg guggagaagg     1020

cccuccggga cgccaagcug gacaaggggc agauccagga gaucguccug gugggcggga     1080

gcacccgcau ccccaagauc cagaagcucc ugcaggacuu cuucaacggc aaggagcuga     1140

acaaguccau caaccccgac gaggccgugg cguacggcgc cgccguccag gccgcgaucc     1200

ucaucgggga caagagcgag aacgugcagg accugcugcu ccuggacguc acgccccuga     1260

gccucggcau cgagaccgcc gggggcguga ugaccccgcu gaucaagcgg aacaccacca     1320

uccccaccaa gcagacgcag accuucacca ccuacuccga caaccagagc uccgugcugg     1380

uccaggugua cgagggggag cgcgccauga cgaaggacaa caaccuccug ggcaaguucg     1440

accugaccgg caucccgccc gcgccccgcg gggugcccca gaucgagguc accuucgaca     1500

ucgacgccaa cggcauccuc aacgugaccg ccgccgacaa gagcaccggg aaggagaaca     1560

agaucacgau caccaacgac aagggccggc uguccaagga cgacaucgac cgcauggugc     1620

aggaggccga gcgguacaag agcgaggacg aggccaaccg cgaccggguc gccgcgaaga     1680

acgcccugga guccuacacc uacaacauca agcagaccgu ggaggacgag aagcuccgcg     1740

gcaagaucag cgagcaggac aagaacaaga uccuggacaa gugccaggag gugaucaacu     1800

ggcuggaccg gaaccagaug gccgagaagg acgaguacga gcacaagcag aaggagcucg     1860

agcgcgucug caaccccauc aucuccaagc uguaccaggg cgggcccggg ggcgggagcg     1920

gcggcggggg cuccggggcc agcggcgggc cgacgaucga ggagguggac ugaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  2741
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt1)

<400>  2741
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggucggcau cgaccugggg uuccaguccu gcuacguggc cguggcccgc gcgggcggga      120

ucgagaccau cgccaacgag uacagcgacc ggugcacccc cgccugcauc uccuucggcc      180

cgaagaaccg cagcaucggg gccgccgcga agucccaggu caucagcaac gccaagaaca      240

cggugcaggg cuucaagcgg uuccacggcc gcgccuucuc cgaccccuuc guggaggccg      300

agaaguccaa ccucgcguac gacaucgucc agcugcccac cgggcugacc ggcaucaagg      360

ugaccuacau ggaggaggag cggaacuuca cgaccgagca ggucaccgcc augcuccuga      420

gcaagcugaa ggagaccgcc gagagcgugc ucaagaagcc cgugguggac ugcgucgugu      480

ccgugccgug cuucuacacg gacgccgagc gccggagcgu cauggacgcc acccagaucg      540

cggggcugaa cugccugcgc cucaugaacg agaccaccgc cguggcccug gccuacggca      600

ucuacaagca ggaccugccc gcccucgagg agaagccccg gaacgugguc uucguggaca      660

uggggcacuc cgcguaccag gugagcgucu gcgccuucaa ccgcggcaag cugaaggugc      720

uggccacggc cuucgacacc acccucggcg ggcggaaguu cgacgaggug cuggucaacc      780

acuucugcga ggaguucggc aagaaguaca agcuggacau caaguccaag auccgcgccc      840

uccugcggcu gagccaggag ugcgagaagc ucaagaagcu gauguccgcg aacgccagcg      900

accugccccu cuccaucgag ugcuucauga acgacgugga cgucagcggg accaugaacc      960

gcggcaaguu ccuggagaug ugcaacgacc ugcucgcccg gguggagccg ccccugcgca     1020

gcgugcugga gcagacgaag cucaagaagg aggacaucua cgccgucgag aucgugggcg     1080

gggccacccg gauccccgcg gugaaggaga agaucuccaa guucuucggc aaggagcuga     1140

gcaccacccu gaacgccgac gaggccguca cgcgcgggug cgcccuccag ugcgcgaucc     1200

ugucccccgc cuucaaggug cgggaguuca gcaucaccga cguggucccg uaccccaucu     1260

cccugcgcug gaacagcccc gccgaggagg gcuccagcga cugcgaggug uucuccaaga     1320

accacgccgc ccccuucagc aaggugcuca ccuucuaccg gaaggagccg uucacccugg     1380

aggcguacua cuccagcccc caggaccugc ccuaccccga cccggccauc gcccaguucu     1440

ccguccagaa ggugacgccc cagagcgacg gguccagcuc caaggugaag gucaaggugc     1500

gcgugaacgu ccacggcauc uucagcgugu ccagcgccag ccucguggag guccacaagu     1560

ccgaggagaa cgaggagccc auggagaccg accagaacgc caaggaggag gagaagaugc     1620

aggucgacca ggaggagccc cacguggagg agcagcagca gcagaccccg gcggagaaca     1680

aggccgagag cgaggagaug gagaccuccc aggccggcag caaggacaag aagauggacc     1740

agccgcccca ggccaagaag gccaagguga agacguccac cguggaccug cccaucgaga     1800

accagcugcu cuggcagauc gaccgcgaga ugcugaaccu guacaucgag aacgagggga     1860

agaugaucau gcaggacaag cucgagaagg agcggaacga cgcgaagaac gccguggagg     1920

aguacgucua cgagaugcgc gacaagcuga gcggcgagua cgagaaguuc guguccgagg     1980

acgaccggaa cagcuucacc cugaagcucg aggacaccga gaacuggcug uacgaggacg     2040

gggaggacca gcccaagcag gucuacgugg acaagcuggc cgagcugaag aaccucggcc     2100

agcccaucaa gauccgcuuc caggaguccg aggagcggcc caagcuguuc gaggagcugg     2160

ggaagcagau ccagcaguac augaagauca ucagcuccuu caagaacaag gaggaccagu     2220

acgaccaccu cgacgccgcg gacaugacga agguggagaa guccaccaac gaggccaugg     2280

aguggaugaa caacaagcug aaccugcaga acaagcagag ccucaccaug gacccggugg     2340

ucaagagcaa ggagaucgag gccaagauca aggagcugac cuccacgugc agccccauca     2400

ucuccaagcc caagcccaag guggagccgc ccaaggagga gcagaagaac gccgagcaga     2460

acggccccgu ggacggccag ggggacaacc ccggcccgca ggccgcggag caggggaccg     2520

acaccgccgu ccccagcgac agcgacaaga agcugcccga gauggacauc gacugaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  2742
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt1)

<400>  2742
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggucggcau cgaccugggg uuccucaacu gcuacaucgc cguggcccgc uccggcggga      120

ucgagaccau cgcgaacgag uacagcgacc ggugcacccc cgccugcauc ucccugggca      180

gccgcacgcg ggccaucggg aacgccgcca agucccagau cgugaccaac guccgcaaca      240

ccauccacgg cuucaagaag cugcacggcc ggagcuucga cgacccgauc gugcagaccg      300

agcgcauccg gcuccccuac gagcugcaga agaugcccaa cggguccgcg ggcgugaagg      360

uccgcuaccu ggaggaggag cggcccuucg ccaucgagca ggucacgggg augcuccugg      420

ccaagcugaa ggagaccagc gagaacgccc ucaagaagcc gguggcggac ugcgugaucu      480

ccauccccag cuucuucacc gacgccgagc gccgguccgu gauggccgcc gcccaggugg      540

cgggccugaa cugccugcgc cucaugaacg agaccacggc cgucgcccug gccuacggga      600

ucuacaagca ggaccugccg ccccucgacg agaagccccg gaacguggug uucaucgaca      660

ugggccacag cgccuaccag guccuggugu gcgcguucaa caagggcaag cugaaggugc      720

ucgccaccac cuucgacccc uaccucgggg gccgcaacuu cgacgaggcc cuggucgacu      780

acuucugcga cgaguucaag accaaguaca agaucaacgu gaaggagaac ucccgggccc      840

ugcugcgccu guaccaggag ugcgagaagc ucaagaagcu gaugagcgcc aacgcguccg      900

accugccccu caacaucgag ugcuucauga acgaccugga cgugagcucc aagaugaacc      960

gggcccaguu cgagcagcug ugcgccagcc uccuggcccg cgucgagccc ccgcugaagg     1020

ccgugaugga gcaggcgaac cuccagcggg aggacaucuc cagcaucgag aucgucgggg     1080

gcgccacgcg cauccccgcc gugaaggagc agaucaccaa guucuuccug aaggacauca     1140

gcaccacccu gaacgccgac gaggcggugg cccggggcug cgcccuccag ugcgccaucc     1200

ugucccccgc cuucaagguc cgcgaguuca gcaucacgga ccuggugccc uacuccauca     1260

cccuccgcug gaagaccagc uucgaggacg gguccggcga gugcgaggug uucugcaaga     1320

accacccggc gcccuucagc aaggucauca ccuuccacaa gaaggagccc uucgagcugg     1380

aggccuucua cacgaaccug cacgaggugc ccuacccgga cgcccggauc ggguccuuca     1440

ccauccagaa cguguucccc cagagcgacg gcgacuccag caaggucaag gugaaggugc     1500

gcgucaacau ccacgggauc uucuccgugg ccagcgccuc cgugaucgag aagcagaacc     1560

ucgagggcga ccacagcgac gcgcccaugg agaccgagac cuccuucaag aacgagaaca     1620

aggacaacau ggacaagaug caggucgacc aggaggaggg ccaccagaag ugccacgccg     1680

agcacacgcc cgaggaggag aucgaccaca ccggggccaa gaccaagagc gccguguccg     1740

acaagcagga ccggcugaac cagacccuga agaagggcaa ggucaagagc aucgaccucc     1800

cgauccaguc cagccugugc cgccagcugg ggcaggaccu ccugaacagc uacaucgaga     1860

acgagggcaa gaugaucaug caggacaagc uggagaagga gcggaacgac gccaagaacg     1920

cgguggagga guacguguac gacuuccgcg accggcuggg gacgguguac gagaaguuca     1980

ucacccccga ggaccucucc aagcugagcg ccguccugga ggacaccgag aacuggcucu     2040

acgaggacgg cgaggaccag cccaagcagg ucuacgugga caagcugcag gagcugaaga     2100

aguacggcca gcccauccag augaaguaca uggagcacga ggagcgcccg aaggcccuca     2160

acgaccuggg gaagaagauc cagcugguga ugaaggugau cgaggccuac cggaacaagg     2220

acgagcgcua cgaccaccuc gaccccaccg agauggagaa gguggagaag ugcaucuccg     2280

acgcgaugag cuggcugaac uccaagauga acgcccagaa caagcugagc cucacgcagg     2340

accccgucgu gaaggugucc gagaucgucg ccaagagcaa ggagcuggac aacuucugca     2400

acccgaucau cuacaagccc aagcccaagg ccgaggugcc cgaggacaag ccgaaggcca     2460

acuccgagca caacggcccc auggacgggc agagcggcac cgagaccaag uccgacagca     2520

ccaaggacuc cagccagcac acgaagucca gcggggagau ggagguggac ugaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  2743
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt1)

<400>  2743
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ugagccucgu ggccgccaug cugcugcucc uguccgcggc ccgcgccgag gaggaggaca      120

agaaggagga cgucggcacc guggugggga ucgaccuggg caccacguac agcugcgucg      180

ggguguucaa gaacggccgg guggagauca ucgccaacga ccaggggaac cgcaucaccc      240

ccuccuacgu cgccuucacc ccggagggcg agcggcucau cggcgacgcg gccaagaacc      300

agcugaccag caaccccgag aacacggugu ucgacgccaa gcgccugauc gggcggaccu      360

ggaacgaccc cuccgugcag caggacauca aguuccuccc cuucaagguc guggagaaga      420

agaccaagcc guacauccag guggacaucg gcgggggcca gaccaagacg uucgcccccg      480

aggagaucag cgcgaugguc cugaccaaga ugaaggagac cgccgaggcc uaccugggga      540

agaaggugac ccacgccgug gucacggugc ccgccuacuu caacgacgcg cagcgccagg      600

ccaccaagga cgccggcacc aucgccggcc ucaacgugau gcggaucauc aacgagccca      660

ccgccgcggc caucgccuac gggcuggaca agcgcgaggg cgagaagaac auccuggucu      720

ucgaccucgg gggcggcacg uucgacgugu cccugcugac caucgacaac gggguguucg      780

aggucguggc caccaacggc gacacccacc ucgggggcga ggacuucgac cagcggguga      840

uggagcacuu caucaagcug uacaagaaga agacggggaa ggacguccgc aaggacaacc      900

gggccgugca gaagcugcgc cgggaggucg agaaggcgaa gcgcgcccuc agcucccagc      960

accaggcccg gaucgagauc gagagcuucu acgagggcga ggacuucucc gagacccuga     1020

cccgcgccaa guucgaggag cugaacaugg accucuuccg gagcaccaug aagccggugc     1080

agaaggugcu ggaggacucc gaccugaaga aguccgacau cgacgagauc guccucgugg     1140

gcgggagcac gcgcaucccc aagauccagc agcuggugaa ggaguucuuc aacggcaagg     1200

agcccagccg ggggaucaac cccgacgagg ccgucgcgua cggcgccgcc gugcaggccg     1260

gggugcuguc cggcgaccag gacaccggcg accucguccu gcuggacgug ugcccgcuca     1320

cccuggggau cgagaccgug ggcgggguca ugacgaagcu gaucccccgc aacaccgugg     1380

ugcccaccaa gaagucccag aucuucagca ccgcgagcga caaccagccc acggucacca     1440

ucaaggugua cgagggcgag cggccgcuca ccaaggacaa ccaccuccug gggaccuucg     1500

accugacggg caucccgccc gcgccccgcg gcgugcccca gaucgagguc accuucgaga     1560

ucgacgugaa cgggauccug cgcgugaccg ccgaggacaa gggcaccggg aacaagaaca     1620

agaucaccau cacgaacgac cagaaccggc ugacccccga ggagaucgag cgcaugguca     1680

acgacgccga gaaguucgcc gaggaggaca agaagcucaa ggagcggauc gacacccgca     1740

acgagcugga gagcuacgcc uacucccuga agaaccagau cggcgacaag gagaagcucg     1800

gcgggaagcu gagcuccgag gacaaggaga ccauggagaa ggccguggag gagaagaucg     1860

aguggcugga gagccaccag gacgccgaca ucgaggacuu caaggccaag aagaaggagc     1920

ucgaggagau cgugcagccc aucaucucca agcuguacgg cagcgccggg cccccgccca     1980

cgggcgagga ggacaccgcg gagaaggacg agcugugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  2744
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt1)

<400>  2744
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

cgccccgcga gcuggccgug ggcaucgacc ucgggaccac cuacagcugc gucggcgugu      120

uccagcaggg gcggguggag auccuggcca acgaccaggg caaccgcacg accccguccu      180

acgucgccuu caccgacacc gagcggcugg ugggggacgc cgccaagagc caggccgcgc      240

ucaaccccca caacacggug uucgacgcca agcgccugau cggccggaag uucgccgaca      300

ccaccgucca guccgacaug aagcacuggc ccuuccgcgu ggugagcgag ggcgggaagc      360

ccaagguccg ggugugcuac cgcggcgagg acaagaccuu cuacccggag gagaucucca      420

gcauggugcu guccaagaug aaggagacgg ccgaggcgua ccucgggcag cccgucaagc      480

acgccgugau caccgugccc gccuacuuca acgacagcca gcggcaggcc accaaggacg      540

ccggcgcgau cgccgggcug aacguccugc gcaucaucaa cgagcccacc gccgccgcca      600

ucgcguacgg ccucgaccgg cgcggcgccg gggagcggaa cgugcugauc uucgaccugg      660

gcgggggcac guucgacgug uccguccuca gcaucgacgc cggcguguuc gaggugaagg      720

ccaccgccgg ggacacccac cugggcgggg aggacuucga caaccgccug gucaaccacu      780

ucauggagga guuccggcgc aagcacggca aggaccucuc cgggaacaag cgggcgcugc      840

gccggcugcg caccgccugc gagcgggcca agcgcacgcu cagcuccagc acccaggcca      900

cccuggagau cgacucccug uucgagggcg uggacuucua caccagcauc acgcgcgccc      960

gguucgagga gcucugcucc gaccuguucc gcagcacccu ggagccggug gagaaggcgc     1020

uccgggacgc caagcuggac aaggcccaga uccacgacgu cgugcugguc ggcgggucca     1080

cccgcauccc caaggugcag aagcuccugc aggacuucuu caacggcaag gagcugaaca     1140

agagcaucaa ccccgacgag gccguggcgu acggggccgc cguccaggcc gccgugcuca     1200

ugggcgacaa gugcgagaag gugcaggacc ugcugcuccu ggacgucgcg ccccugagcc     1260

ucgggcugga gaccgccggc ggcgugauga cgacccugau ccagcggaac gccaccaucc     1320

cgaccaagca gacgcagacc uucaccaccu acuccgacaa ccagcccggg guguucaucc     1380

aggucuacga gggcgagcgc gccaugacga aggacaacaa ccuccugggg cgguucgagc     1440

ugagcggcau cccgcccgcg ccccgcgggg ugccccagau cgaggugacc uucgacaucg     1500

acgccaacgg cauccucucc gucaccgcca ccgaccggag cacgggcaag gccaacaaga     1560

ucaccaucac caacgacaag gggcgccugu ccaaggagga gguggagcgg auggugcacg     1620

aggccgagca guacaaggcc gaggacgagg cgcagcgcga ccgggucgcc gccaagaaca     1680

gccuggaggc ccacguguuc cacgugaagg gcucccucca ggaggagagc cugcgcgaca     1740

agauccccga ggaggaccgg cgcaagaugc aggacaagug ccgggagguc cuggcguggc     1800

ucgagcacaa ccagcuggcc gagaaggagg aguacgagca ccagaagcgc gagcuggagc     1860

agaucugccg gcccaucuuc ucccgccugu acgggggccc gggcgugccc gggggcagcu     1920

ccugcgggac ccaggcccgc cagggcgacc ccagcaccgg gcccaucauc gaggaggugg     1980

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  2745
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt1)

<400>  2745
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

cgccccgcga gcuggccgug ggcaucgacc ucgggaccac cuacagcugc gucggcgugu      120

uccagcaggg gcggguggag auccuggcca acgaccaggg caaccgcacg accccguccu      180

acgucgccuu caccgacacc gagcggcugg ugggggacgc cgccaagagc caggccgcgc      240

ucaaccccca caacacggug uucgacgcca agcgccugau cggccggaag uucgccgaca      300

ccaccgucca guccgacaug aagcacuggc ccuuccaggu ggugagcgag ggcgggaagc      360

ccaagguccg cgugugcuac cggggcgagg acaagaccuu cuacccggag gagaucucca      420

gcauggugcu guccaagaug aaggagacgg ccgaggcgua ccucgggcag cccgucaagc      480

acgccgugau caccgugccc accuacuuca gcaacuccca gcgccaggcc accaaggacg      540

ccggcgccau cgcggggcug aagguccugc ccaucaucaa cgaggccacg gccgccgcca      600

ucgcguacgg ccucgaccgg cgcggcgccg ggaagcggaa cgugcugauc uucgaccugg      660

gcgggggcac cuucgacgug agcguccucu ccaucgacgc cggcguguuc gaggugaagg      720

ccaccgccgg ggacacccac cugggcgggg aggacuucga caaccgccug gucaaccacu      780

ucauggagga guuccggcgc aagcacggca aggaccucag cgggaacaag cgggcgcugc      840

gccggcugcg cacggccugc gagcgggcca agcgcacccc guccagcucc acccaggcca      900

cccucgagau cgacagccug uucgagggcg uggacuucua caaguccauc acgcgggccc      960

gcuucgagga gcugugcagc gaccucuucc gcuccacccu ggagcccgug gagaaggcgc     1020

ugcgggacgc caagcucgac aaggcccaga uccacgacuu cguccugggc gggggccugc     1080

acagccaccc ccagggggcc gagguggcgg ccggccuccu gcagcgccag ggggccgagc     1140

aggagcacca gcccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  2746
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt1)

<400>  2746
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagca       60

agggccccgc cguggggauc gaccugggca ccaccuacuc cugcgucggg guguuccagc      120

acggcaaggu ggagaucauc gccaacgacc aggggaaccg cacgaccccc agcuacgucg      180

cguucaccga caccgagcgg cucaucggcg acgccgccaa gaaccaggug gccaugaacc      240

ccacgaacac cguguucgac gccaagcgcc ugaucggccg gcgcuucgac gacgcggucg      300

ugcaguccga caugaagcac uggcccuuca ugguggucaa cgacgccggg cggcccaagg      360

uccaggugga guacaagggc gagaccaaga gcuucuaccc ggaggaggug uccagcaugg      420

ugcugaccaa gaugaaggag aucgccgagg ccuaccucgg gaagacggug accaacgcgg      480

ucgugaccgu gcccgccuac uucaacgacu cccagcgcca ggccaccaag gacgccggca      540

cgaucgccgg gcugaacguc cugcggauca ucaacgagcc caccgcggcc gccaucgccu      600

acggccucga caagaaggug ggcgccgagc gcaacgugcu gaucuucgac cucgggggcg      660

ggaccuucga cgucagcauc cugaccaucg aggacggcau cuucgaggug aaguccacgg      720

cgggcgacac ccaccucggg ggcgaggacu ucgacaaccg gauggugaac cacuucaucg      780

ccgaguucaa gcgcaagcac aagaaggaca ucagcgagaa caagcgggcc guccgccggc      840

ugcgcaccgc cugcgagcgg gccaagcgca cccuguccag cuccacgcag gcgagcaucg      900

agaucgacuc ccuguacgag gggaucgacu ucuacaccag caucacccgg gcccgcuucg      960

aggagcugaa cgccgaccuc uuccggggca cccuggaccc cguggagaag gcccugcgcg     1020

acgccaagcu cgacaagucc cagauccacg acaucguccu ggucgggggc agcacgcgga     1080

ucccgaagau ccagaagcug cuccaggacu ucuucaacgg caaggagcug aacaagucca     1140

ucaaccccga cgaggcggug gccuacgggg ccgccgugca ggcggccauc cugagcggcg     1200

acaagagcga gaacgugcag gaccuccugc ugcucgacgu gacgccccug ucccugggga     1260

ucgagaccgc cggcgggguc augaccgugc ucaucaagcg caacaccacc auccccacca     1320

agcagaccca gacguucacc accuacagcg acaaccagcc gggcgugcug auccaggucu     1380

acgagggcga gcgcgccaug accaaggaca acaaccugcu cgggaaguuc gagcugacgg     1440

gcaucccgcc cgcgccccgc ggggugcccc agaucgaggu gaccuucgac aucgacgcca     1500

acggcauccu gaacgucucc gccguggaca agagcaccgg gaaggagaac aagaucacca     1560

ucaccaacga caagggccgg cucuccaagg aggacaucga gcggauggug caggaggccg     1620

agaaguacaa ggccgaggac gagaagcagc gcgacaaggu cagcuccaag aacagccugg     1680

aguccuacgc cuucaacaug aaggcgacgg uggaggacga gaagcugcag ggcaagauca     1740

acgacgagga caagcagaag auccucgaca agugcaacga gaucaucaac uggcuggaca     1800

agaaccagac cgccgagaag gaggaguucg agcaccagca gaaggagcug gagaaggugu     1860

gcaaccccau caucaccaag cucuaccaga gcgccggggg caugcccggg ggcaugcccg     1920

gcggguuccc gggcgggggc gccccgcccu ccgggggcgc cagcuccggc cccaccaucg     1980

aggaggucga cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  2747
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt1)

<400>  2747
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauca       60

gcgccucccg cgccgcggcc gcccggcugg ugggcgccgc cgcgagccgc gggcccaccg      120

ccgcccggca ccaggacucc uggaacggcc ucagccacga ggccuuccgc cuggucuccc      180

ggcgcgacua cgcgagcgag gccaucaagg gggccguggu gggcaucgac cuggggacca      240

cgaacuccug cgucgccgug auggagggca agcaggccaa ggugcucgag aacgcggagg      300

gcgcccggac caccccgagc gucguggccu ucaccgccga cggggagcgc cuggugggca      360

ugcccgccaa gcggcaggcg gucacgaacc ccaacaacac cuucuacgcc accaagcgcc      420

ugaucgggcg gcgcuacgac gaccccgagg ugcagaagga caucaagaac gugccguuca      480

agaucguccg ggccuccaac ggcgacgccu ggguggaggc ccacgggaag cucuacagcc      540

ccucccagau cggcgcguuc gugcugauga agaugaagga gaccgccgag aacuaccugg      600

gccacacggc caagaacgcc gucaucaccg ugcccgccua cuucaacgac agccagcgcc      660

aggcgaccaa ggacgccggg cagaucuccg gccucaacgu gcugcggguc aucaacgagc      720

ccaccgccgc cgcgcuggcc uacgggcucg acaagagcga ggacaaggug aucgccgugu      780

acgaccuggg cggcgggacg uucgacaucu ccauccugga gauccagaag ggcgucuucg      840

aggucaagag caccaacggg gacaccuucc ucggcgggga ggacuucgac caggcccugc      900

ugcgccacau cgugaaggag uucaagcggg agaccggcgu ggaccucacg aaggacaaca      960

uggcccugca gcgcgugcgg gaggcggccg agaaggccaa gugcgagcug uccagcuccg     1020

uccagaccga caucaaccuc ccguaccuga ccauggacag cagcggcccc aagcaccuga     1080

acaugaagcu cacccgcgcc caguucgagg ggaucgugac ggaccugauc cggcgcacca     1140

ucgcccccug ccagaaggcg augcaggacg ccgagguguc caagagcgac aucggcgagg     1200

ucauccuggu cgggggcaug acccgcaugc ccaaggugca gcagaccgug caggaccucu     1260

ucgggcgggc cccguccaag gccgugaacc ccgacgaggc cguggcgauc ggcgccgcca     1320

uccagggcgg gguccuggcc ggcgacguga cggacgugcu gcuccuggac gucacgcccc     1380

ugagccucgg gaucgagacc cugggcgggg uguucaccaa gcugaucaac cgcaacacca     1440

ccauccccac caagaagucc cagguguuca gcaccgcggc cgacggccag acgcaggucg     1500

agaucaaggu gugccagggc gagcgggaga uggccgggga caacaagcuc cugggccagu     1560

ucacccugau cgggaucccg cccgcgcccc gcggcgugcc ccagaucgag gucaccuucg     1620

acaucgacgc caacggcauc gugcacgugu ccgccaagga caaggggacc ggccgggagc     1680

agcagaucgu cauccagagc uccgggggcc ucagcaagga cgacaucgag aacaugguga     1740

agaacgccga gaaguacgcc gaggaggacc gccggaagaa ggagcgcgug gaggccguca     1800

acauggccga ggggaucauc cacgacacgg agaccaagau ggaggaguuc aaggaccagc     1860

ugccggcgga cgagugcaac aagcugaagg aggagaucuc caagaugcgg gagcuccugg     1920

cccgcaagga cagcgagacc ggcgagaaca uccggcaggc cgccuccagc cugcagcagg     1980

ccucccucaa gcuguucgag auggcguaca agaagauggc cagcgagcgc gagggcuccg     2040

ggagcuccgg caccggggag cagaaggagg accagaagga ggagaagcag ugaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  2748
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt1)

<400>  2748
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaggaggc cggcgggagc gacggccccc gcgagaccgc gccgaccucc gccuacagcu      120

cccccgcccg gagccugggg gacacgggca ucacgccccu cucccccagc cacaucguga      180

acgacaccga cuccaacguc agcgagcagc aguccuuccu gguggugguc gccguggacu      240

ucgggaccac cagcuccggc uacgccuaca gcuucaccaa ggagccggag ugcauccacg      300

ugaugcgccg gugggagggc ggggaccccg gcgucuccaa ccagaagacc cccaccacga      360

uccugcucac ccccgagcgc aaguuccaca gcuucgggua cgcggcccgg gacuucuacc      420

acgaccugga cccgaacgag gccaagcagu ggcuguaccu cgagaaguuc aagaugaagc      480

ugcacaccac cggcgaccug acgauggaca ccgaccucac cgccgcgaac gggaagaagg      540

ugaaggcccu ggagaucuuc gccuacgccc ugcaguacuu caaggagcag gcccucaagg      600

agcuguccga ccaggcgggc agcgaguucg agaacuccga cgugcgcugg gucaucaccg      660

ugcccgccau cuggaagcag cccgccaagc aguucaugcg gcaggccgcc uaccaggcgg      720

gccuggccag ccccgagaac uccgagcagc ucaucaucgc ccuggagccg gaggccgcca      780

gcaucuacug ccgcaagcug cggcuccacc agaugaucga gcugagcucc aaggcggccg      840

ugaacgggua cagcggcucc gacacggucg gggccggcuu cacccaggcc aaggagcaca      900

uccgccggaa ccgccagagc cggaccuucc ugguggagaa cgugaucggc gagaucuggu      960

ccgagcucga ggagggggac aaguacgucg ugguggacag cggcgggggc accgucgacc     1020

ugacggugca ccagauccgc cugcccgagg ggcaccucaa ggagcuguac aaggccaccg     1080

gcggccccua cgggucccug ggcguggacu acgaguucga gaagcuccug uacaagaucu     1140

ucggggagga cuucaucgag caguucaaga ucaagcggcc cgcggccugg gucgaccuga     1200

ugaucgccuu cgagagccgc aagcgggccg cggccccgga ccgcaccaac ccccucaaca     1260

ucacccugcc cuucuccuuc aucgacuacu acaagaaguu ccggggccac agcguggagc     1320

acgcccugcg caaguccaac guggacuucg ucaaguggag cucccagggg augcuccgga     1380

ugagccccga cgccaugaac gcccuguuca agccgacgau cgacuccauc aucgagcacc     1440

uccgcgaccu guuccagaag cccgagguga gcaccgucaa guuccuguuc cuggugggcg     1500

gcuucgcgga ggcgccccuc cugcagcagg ccgugcaggc cgccuucggg gaccagugcc     1560

gcaucaucau cccccaggac gucggccuga ccauccucaa gggggccgug cuguucggcc     1620

uggacccggc cgugaucaag guccggcgca gcccccucac cuacggggug ggcgugcuga     1680

accgguacgu cgagggcaag cacccgcccg agaagcugcu cgugaaggac gggacgcgcu     1740

ggugcaccga cguguucgac aaguucaucu ccgccgacca guccgucgcc cugggcgagc     1800

uggugaagcg gagcuacacc cccgccaagc ccagccagcu ggugaucguc aucaacaucu     1860

acuccagcga gcacgacaac guguccuuca ucaccgaccc cggggugaag aagugcggca     1920

cgcuccgccu ggaccugacc ggcaccagcg ggaccgcggu cccggcccgg cgcgagaucc     1980

agacgcucau gcaguucggc gacaccgaga ucaaggccac cgccaucgac aucgcgaccu     2040

ccaagagcgu gaaggugggg aucgacuucc ugaacuacug aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  2749
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt1)

<400>  2749
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugg       60

ccgugcccga gaugggccuc caggggcugu acaucggcag cucccccgag cgcagccccg      120

uccccucccc gcccgggagc ccccggaccc aggaguccug cggcaucgcc ccgcugaccc      180

ccagccaguc ccccaagccc gaggugcgcg cgccccagca ggccagcuuc uccguggucg      240

uggccaucga cuucgggacg accagcuccg gcuacgccuu cagcuucgcc uccgaccccg      300

aggcgaucca caugaugcgg aagugggagg gcggggaccc gggcguggcc caccagaaga      360

ccccgaccug ccuccugcug acgcccgagg gggccuucca cagcuucggc uacaccgccc      420

gcgacuacua ccacgaccuc gaccccgagg aggcgcggga cuggcuguac uucgagaagu      480

ucaagaugaa gauccacucc gccaccgacc ugacccucaa gacgcagcug gaggccguca      540

acgggaagac caugcccgcc cuggaggugu ucgcccacgc gcuccgcuuc uuccgggagc      600

acgcccugca ggagcugcgc gagcagagcc ccucccuccc cgagaaggac accgugcggu      660

ggguccugac cgugcccgcc aucuggaagc agccggccaa gcaguucaug cgcgaggccg      720

cguaccuggc cggccucgug agccgggaga acgccgagca gcugcugauc gcccucgagc      780

ccgaggccgc guccgucuac ugccgcaagc ugcggcugca ccagcuccug gaccugagcg      840

gccgcgcccc cgggggcggg cggcucggcg agcgccggag caucgacucc agcuuccgcc      900

aggcccggga gcagcugcgc cggucccgcc acagccgcac guuccuggug gaguccggcg      960

ugggggagcu cugggccgag augcaggccg gcgaccggua cgucguggcg gacugcgggg     1020

gcgggaccgu ggaccugacc guccaccagc uggagcagcc ccacggcacc cucaaggagc     1080

uguacaaggc cagcggcggg ccguacggcg ccgugggggu ggaccuggcc uucgagcagc     1140

uccugugccg caucuucggc gaggacuuca ucgcgacguu caagcggcag cgccccgccg     1200

ccugggucga ccugaccauc gccuucgagg cccggaagcg caccgcgggg ccccaccggg     1260

ccggcgcccu caacaucucc cugcccuuca gcuucaucga cuucuaccgc aagcagcggg     1320

gccacaacgu ggagaccgcc cugcgccggu ccagcgugaa cuucgucaag ugguccagcc     1380

aggggaugcu ccgcaugucc ugcgaggcca ugaacgagcu guuccagccg acggugagcg     1440

gcaucaucca gcacaucgag gcgcugcucg cccggcccga gguccagggg gugaagcugc     1500

uguuccucgu gggcggguuc gccgaguccg ccguccugca gcacgccgug caggcggccc     1560

ugggcgcccg cggccugcgg guggucgugc cccacgacgu ggggcucacc auccugaagg     1620

gcgccguccu guucgggcag gcgccgggcg uggugcgcgu ccggcgcagc ccccucaccu     1680

acggcguggg ggugcugaac cgguucgucc ccggccgcca cccgcccgag aagcugcucg     1740

ugcgcgacgg gcggcgcugg ugcaccgacg uguucgagcg guucgucgcc gccgagcagu     1800

ccguggcccu gggcgaggag gugcgccgga gcuacugccc cgcccgcccc gggcagcggc     1860

gcguccugau caaccucuac ugcugcgcgg ccgaggacgc ccgguucauc acggaccccg     1920

gcgugcgcaa gugcggcgcc cugucccugg agcucgagcc ggccgacugc gggcaggaca     1980

ccgcgggcgc cccgcccggg cggcgcgaga uccgggccgc caugcaguuc ggcgacaccg     2040

agaucaaggu gaccgccguc gacgugagca cgaaccgcag cgugcgggcg uccaucgacu     2100

uccugagcaa cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  2750
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt1)

<400>  2750
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

gggagaugac cauccugggc agcgccgugc ucacccugcu gcucgcgggg uaccuggccc      120

agcaguaccu gccccucccg acgcccaagg ucaucggcau cgaccugggg accaccuacu      180

gcuccguggg cguguucuuc cccgggaccg gcaaggucaa ggugaucccc gacgagaacg      240

gccacaucag caucccgucc auggugagcu ucacggacaa cgacgucuac gugggguacg      300

aguccgugga gcuggccgac agcaaccccc agaacaccau cuacgacgcc aagcgguuca      360

ucggcaagau cuucaccgcc gaggagcucg aggcggagau cgggcgcuac cccuucaagg      420

uccugaacaa gaacggcaug guggaguucu ccgugaccag caacgagacg aucaccgucu      480

cccccgagua cguggggagc cggcugcucc ugaagcugaa ggagauggcc gaggccuacc      540

ucggcaugcc gguggccaac gcggucaucu ccgugcccgc cgaguucgac cugaagcagc      600

gcaacagcac caucgaggcc gccaaccugg ccggccucaa gauccugcgg gugaucaacg      660

agcccaccgc ggccgccaug gccuacgggc ugcacaaggc cgacgucuuc cacgugcucg      720

ugaucgaccu gggcgggggc acgcuggacg ucucccuccu gaacaagcag ggcgggaugu      780

uccugacccg cgcgaugagc ggcaacaaca agcucggggg ccaggacuuc aaccagcggc      840

ugcugcagua ccucuacaag cagaucuacc agaccuacgg guucgugccc ucccgcaagg      900

aggagaucca ccggcugcgc caggccgugg agauggucaa gcugaaccuc acccugcacc      960

agagcgccca gcuguccgug cuccugacgg ucgaggagca ggaccggaag gagccgcaca     1020

gcuccgacac cgagcugccc aaggacaagc ucagcagcgc cgacgaccac cgcgugaacu     1080

ccggcuucgg ccgggggcug agcgacaaga aguccggcga gagccaggug cuguucgaga     1140

ccgagaucuc ccgcaagcug uucgacaccc ugaacgagga ccuguuccag aagauccucg     1200

uccccaucca gcagguccug aaggaggggc accuggagaa gacggagauc gacgaggugg     1260

ugcucguggg cgggagcacc cggauccccc gcauccgcca ggugauccag gaguucuucg     1320

gcaaggaccc gaacaccucc gucgaccccg accuggccgu ggugaccggc gucgcgaucc     1380

aggccgggau cgacggcggg agcuggcccc uccagguguc cgcccuggag auccccaaca     1440

agcaccucca gaagacgaac uucaacugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  2751
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt1)

<400>  2751
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ccaucggcgu gcaccugggg ugcaccagcg cgugcgucgc cguguacaag gacggccgcg      120

ccgggguggu cgccaacgac gccggcgacc gggugacccc cgcggugguc gccuacuccg      180

agaacgagga gaucgugggg cucgccgcca agcagagccg cauccggaac aucuccaaca      240

cggugaugaa ggucaagcag auccugggcc gcagcuccag cgacccgcag gcgcagaagu      300

acaucgccga guccaagugc cuggugaucg agaagaacgg caagcuccgg uacgagaucg      360

acaccgggga ggagaccaag uucgugaacc ccgaggacgu cgcccgccug aucuucagca      420

agaugaagga gaccgcccac uccgugcugg gcagcgacgc caacgacgug gucaucacgg      480

ugcccuucga cuucggggag aagcagaaga acgcgcucgg cgaggccgcc cgggccgccg      540

gguucaacgu gcugcgccug auccacgagc ccuccgcggc ccuccuggcc uacggcaucg      600

gccaggacag cccgaccggg aaguccaaca uccuggucuu caagcucggc gggaccagcc      660

ugucccugag cgugauggag gugaacuccg gcaucuaccg gguccucagc accaacacgg      720

acgacaacau cggcggggcc cacuucaccg agacccuggc ccaguaccug gcguccgagu      780

uccagcgcag cuucaagcac gacgugcggg gcaacgcccg cgccaugaug aagcucacca      840

acagcgccga gguggccaag cacucccuga gcacgcuggg guccgcgaac ugcuuccucg      900

acagccugua cgagggccag gacuucgacu gcaacgucuc ccgggcccgc uucgagcugc      960

ucugcagccc ccuguucaac aagugcaucg aggccauccg ggggcugcuc gaccagaacg     1020

gcuucaccgc cgacgacauc aacaaggugg uccugugcgg cggguccagc cgcaucccca     1080

agcugcagca gcucaucaag gaccuguucc ccgcggugga gcugcucaac uccaucccgc     1140

ccgacgaggu gauccccauc ggcgccgcca ucgaggccgg gauccugauc ggcaaggaga     1200

accugcucgu cgaggacagc cugaugaucg agugcuccgc ccgggacauc cuggugaagg     1260

ggguggacga gagcggcgcg ucccgcuuca ccguccucuu ccccagcggc accccgcugc     1320

ccgcccggcg ccagcacacg cugcaggccc ccggguccau cagcuccgug ugccucgagc     1380

uguacgagag cgacggcaag aacuccgcca aggaggagac caaguucgcc cagguggucc     1440

ugcaggaccu cgacaagaag gagaacgggc ugcgggacau ccuggcggug cucaccauga     1500

agcgcgacgg cagccugcac gugaccugca cggaccagga gaccgggaag ugcgaggcca     1560

ucagcaucga gaucgccucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  2752
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt1)

<400>  2752
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggucggccu ggacgugggg ucccagagcu gcuacaucgc cguggcccgc gcgggcggga      120

ucgagaccau cgccaacgag uucuccgacc ggugcacccc cagcgucauc uccuucggca      180

gcaagaaccg caccaucggg guggccgcca agaaccagca gaucacccac gccaacaaca      240

ccguguccaa cuucaagcgg uuccacggcc gcgcguucaa cgacccguuc auccagaagg      300

agaaggagaa ccucagcuac gaccuggucc cccugaagaa cggcggggug ggcaucaagg      360

ugauguacau gggggaggag caccucuucu ccgucgagca gaucaccgcc augcugcuga      420

cgaagcucaa ggagaccgcc gagaacagcc ugaagaagcc cgugaccgac ugcgugaucu      480

ccguccccag cuucuucacc gacgccgagc ggcgcuccgu gcuggacgcg gcccagaucg      540

ugggccucaa cugccugcgg cugaugaacg acaugacggc cgucgcccuc aacuacggga      600

ucuacaagca ggaccugccg agccuggacg agaagccccg caucguggug uucgucgaca      660

ugggccacuc cgccuuccag gugagcgcgu gcgccuucaa caagggcaag cucaaggugc      720

uggggaccgc cuucgacccc uuccugggcg ggaagaacuu cgacgagaag cucgucgagc      780

acuucugcgc cgaguucaag accaaguaca agcuggacgc caaguccaag auccgggcgc      840

ugcuccgccu guaccaggag ugcgagaagc ugaagaagcu caugagcucc aacagcaccg      900

accugccccu gaacaucgag ugcuucauga acgacaagga cgugagcggc aagaugaacc      960

ggucccaguu cgaggagcuc ugcgccgagc ugcugcagaa gaucgaggug ccgcucuaca     1020

gccugcugga gcagacgcac cucaaggucg aggacguguc cgccgucgag aucgugggcg     1080

gggccacccg cauccccgcc gugaaggagc ggaucgcgaa guucuucggc aaggacauca     1140

gcaccacccu gaacgccgac gaggccgucg cccgcgggug cgcccugcag ugcgcgaucc     1200

ucucccccgc cuucaaggug cgggaguuca gcgugacgga cgccgucccc uucccgaucu     1260

cccugaucug gaaccacgac agcgaggaca ccgagggcgu gcacgaggug uucucccgca     1320

accacgccgc gcccuucagc aagguccuga ccuuccuccg gcgcgggccc uucgagcugg     1380

aggccuucua cuccgacccc cagggcgugc cguaccccga ggccaagauc ggccgguucg     1440

ugguccagaa cgugagcgcc cagaaggacg gggagaaguc ccgcgugaag gucaaggugc     1500

gggugaacac ccacggcauc uucacgauca gcaccgccuc cauggucgag aaggugccca     1560

ccgaggagaa cgagaugagc uccgaggcgg acauggagug ccugaaccag cggcccccgg     1620

agaaccccga caccgacaag aacgugcagc aggacaacag cgaggccggg acgcagcccc     1680

agguccagac cgacgcccag cagaccuccc agagcccgcc cagccccgag cucaccuccg     1740

aggagaacaa gauccccgac gccgacaagg ccaacgagaa gaagguggac cagcccccgg     1800

aggcgaagaa gcccaagauc aaggugguca acguggagcu gcccaucgag gccaaccugg     1860

uguggcagcu cggcaaggac cugcugaaca uguacaucga gacggagggg aagaugauca     1920

ugcaggacaa gcucgagaag gagcgcaacg acgccaagaa cgccgucgag gaguacgugu     1980

acgaguuccg cgacaagcug ugcggcccgu acgagaaguu caucugcgag caggaccacc     2040

agaacuuccu gcgccugcuc accgagaccg aggacuggcu guacgaggag ggcgaggacc     2100

aggccaagca ggcguacgug gacaagcugg aggagcucau gaagaucggg acccccguca     2160

aggugcgguu ccaggaggcc gaggagcgcc ccaagauguu cgaggagcug ggccagcggc     2220

ugcagcacua cgccaagauc gccgcggacu uccgcaacaa ggacgagaag uacaaccaca     2280

ucgacgagag cgagaugaag aagguggaga aguccgucaa cgaggugaug gaguggauga     2340

acaacgugau gaacgcccag gccaagaagu cccucgacca ggaccccguc gugcgggccc     2400

aggagaucaa gacgaagauc aaggagcuga acaacacgug cgagccggug gucacccagc     2460

ccaagcccaa gaucgagagc cccaagcugg agcgcacccc gaacgggccc aacaucgaca     2520

agaaggagga ggaccucgag gacaagaaca acuucggcgc cgagccgccc caccagaacg     2580

gggagugcua ccccaacgag aagaacagcg ugaacaugga ccuggacuga ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  2753
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt1)

<400>  2753
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaggugcg ccggcagcgc ccccggcgcc gggucugcug ggcccuggug gcggugcucc      120

uggccgaccu gcucgcccug agcgacaccc uggccgucau guccguggac cucggcagcg      180

aguccaugaa gguggccauc gucaagccgg gggugcccau ggagaucgug cugaacaagg      240

agagccgccg gaagaccccc gucaucguga cgcugaagga gaacgagcgc uucuucggcg      300

acuccgcggc cagcauggcc aucaagaacc ccaaggccac ccuccgguac uuccagcacc      360

uccuggggaa gcaggcggac aacccgcacg uggcccugua ccaggcccgc uuccccgagc      420

acgagcugac cuucgacccc cagcggcaga ccguccacuu ccagaucucc agccagcugc      480

aguucucccc cgaggaggug cucggcaugg ugcugaacua cagccgcucc cuggccgagg      540

acuucgccga gcagccgauc aaggacgcgg ucaucacggu gcccguguuc uucaaccagg      600

ccgagcggcg cgccguccuc caggccgccc ggauggcggg gcugaaggug cugcagcuca      660

ucaacgacaa caccgccacc gcccugagcu acggcguguu ccgccggaag gacaucaaca      720

ccacggccca gaacaucaug uucuacgaca ugggcuccgg gagcaccguc ugcaccaucg      780

ugaccuacca gauggugaag acgaaggagg ccggcaugca gccccagcug cagauccgcg      840

gggucggcuu cgaccggacc cucgggggcc uggagaugga gcugcgccuc cgggagcgcc      900

uggcgggccu guucaacgag cagcgcaagg ggcagcgggc caaggacgug cgcgagaacc      960

cccgggccau ggccaagcuc cugcgcgagg ccaaccggcu gaagaccguc cucuccgcga     1020

acgccgacca cauggcccag aucgagggcc ugauggacga cguggacuuc aaggccaagg     1080

ugacccgcgu cgaguucgag gagcugugcg cggaccucuu cgagcgggug ccggggcccg     1140

ugcagcaggc ccugcagagc gccgagaugu cccuggacga gaucgagcag gucauccucg     1200

ugggcggcgc cacgcgcgug ccccgggucc aggaggugcu gcugaaggcc guggggaagg     1260

aggagcucgg caagaacauc aacgcggacg aggccgccgc caugggggcc gucuaccagg     1320

cggccgcccu gagcaaggcc uucaagguga agcccuucgu gguccgcgac gccguggugu     1380

acccgauccu ggucgaguuc acccgggagg uggaggagga gcccggcauc cacucccuca     1440

agcacaacaa gcgcgugcug uucagccgga uggggcccua cccccagcgc aaggucauca     1500

ccuucaaccg guacagccac gacuucaacu uccacaucaa cuacggcgac cugggcuucc     1560

ucgggccgga ggaccugcgc guguucggcu cccagaaccu gaccacggug aagcugaagg     1620

gggucggcga cagcuucaag aaguaccccg acuacgaguc caaggggauc aaggcgcacu     1680

ucaaccucga cgagagcggc gugcuguccc uggaccgggu ggagagcguc uucgagaccc     1740

ucguggagga cuccgccgag gaggagagca cccugaccaa gcugggcaac acgaucucca     1800

gccucuucgg gggcgggacc acccccgacg ccaaggagaa cggcaccgac acggugcagg     1860

aggaggagga gucccccgcc gaggggagca aggacgagcc gggcgagcag gucgagcuga     1920

aggaggaggc ggaggccccc guggaggacg gcucccagcc gccgccgccc gagcccaagg     1980

gggacgccac ccccgagggc gagaaggcca ccgagaagga gaacggggac aagagcgagg     2040

cccagaagcc cuccgagaag gcggaggccg gccccgaggg cguggccccc gcccccgagg     2100

gggagaagaa gcagaagccc gcccgcaagc ggcgcauggu cgaggagauc ggcguggagc     2160

uggugguccu cgaccugccc gaccugcccg aggacaagcu cgcgcagagc gugcagaagc     2220

ugcaggaccu gacccuccgc gaccuggaga agcaggagcg ggagaaggcc gccaacuccc     2280

uggaggccuu caucuucgag acgcaggaca agcucuacca gccggaguac caggagguga     2340

gcaccgagga gcagcgcgag gagaucuccg ggaagcugag cgccgcgagc accuggcugg     2400

aggacgaggg cgucggggcc accacgguga ugcucaagga gaagcuggcc gagcugcgga     2460

agcucugcca gggccuguuc uuccgcgugg aggagcggaa gaaguggccc gagcgccugu     2520

ccgcccucga caaccugcug aaccacagcu ccauguuccu caagggcgcg cggcugaucc     2580

ccgagaugga ccagaucuuc accgaggucg agaugaccac ccuggagaag gugaucaacg     2640

agaccugggc cuggaagaac gccacgcucg ccgagcaggc caagcugccc gcgaccgaga     2700

agccggugcu gcucagcaag gacaucgagg ccaagaugau ggcccuggac cgcgaggucc     2760

aguaccugcu caacaaggcc aaguucacca agccccggcc ccgccccaag gacaagaacg     2820

ggacccgggc cgagccgccc cugaacgcgu ccgccagcga ccagggcgag aaggugaucc     2880

cgcccgccgg gcagacggag gacgccgagc ccaucuccga gcccgagaag guggagaccg     2940

gcagcgagcc cggggacacc gagccccugg agcucggcgg cccgggggcc gagcccgagc     3000

agaaggagca guccaccggc cagaagcgcc cccugaagaa cgacgagcug ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  2754
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt1)

<400>  2754
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggagaccca gacccaggac cagcccaugg aggaggagga gguggagacg uucgccuucc      120

aggccgagau cgcgcagcug augagccuca ucaucaacac cuucuacucc aacaaggaga      180

ucuuccugcg cgagcugauc agcaacucca gcgacgcccu cgacaagauc cgguacgagu      240

cccugaccga ccccagcaag cuggacuccg gcaaggagcu ccacaucaac cugaucccca      300

acaagcagga ccgcacccug acgaucgucg acaccgggau cggcaugacc aaggccgacc      360

ucaucaacaa ccuggggacc aucgccaaga gcggcacgaa ggccuucaug gaggcgcugc      420

aggccggggc cgacaucucc augaucggcc aguucggcgu gggguucuac agcgccuacc      480

ucguggcgga gaaggucacc gugaucacca agcacaacga cgacgagcag uacgccuggg      540

aguccagcgc cggcgggucc uucaccgugc ggacggacac cggcgagccc auggggcgcg      600

gcaccaaggu cauccugcac cugaaggagg accagaccga guaccucgag gagcggcgca      660

ucaaggagau cgugaagaag cacagccagu ucaucggcua cccgaucacg cuguucgugg      720

agaaggagcg ggacaaggag gucuccgacg acgaggccga ggagaaggag gacaaggagg      780

aggagaagga gaaggaggag aaggagagcg aggacaagcc cgagaucgag gacguggggu      840

ccgacgagga ggaggagaag aaggacggcg acaagaagaa gaagaagaag aucaaggaga      900

aguacaucga ccaggaggag cugaacaaga ccaagcccau cuggacccgc aaccccgacg      960

acaucaccaa cgaggaguac ggggaguucu acaagagccu cacgaacgac ugggaggacc     1020

accuggccgu gaagcacuuc uccgucgagg gccagcugga guuccgggcg cuccuguucg     1080

ugccgcgccg ggcccccuuc gaccuguucg agaaccgcaa gaagaagaac aacaucaagc     1140

ucuacgugcg gcgcgucuuc aucauggaca acugcgagga gcugaucccc gaguaccuga     1200

acuucauccg gggcguggug gacagcgagg accucccccu gaacaucagc cgcgagaugc     1260

ugcagcaguc caagauccuc aaggucaucc ggaagaaccu ggugaagaag ugccuggagc     1320

uguucaccga gcucgccgag gacaaggaga acuacaagaa guucuacgag caguucagca     1380

agaacaucaa gcuggggauc cacgaggacu cccagaaccg caagaagcuc agcgagcugc     1440

ugcgguacua caccuccgcc agcggcgacg agaugguguc ccucaaggac uacugcaccc     1500

gcaugaagga gaaccagaag cacaucuacu acaucacggg ggagaccaag gaccaggucg     1560

ccaacagcgc guucguggag cggcugcgca agcacggccu ggaggugauc uacaugaucg     1620

agccgaucga cgaguacugc guccagcagc ucaaggaguu cgaggggaag acccuggugu     1680

ccgucaccaa ggagggccug gagcuccccg aggacgagga ggagaagaag aagcaggagg     1740

agaagaagac gaaguucgag aaccugugca agaucaugaa ggacauccug gagaagaagg     1800

uggagaaggu ggucgugagc aaccgccucg ugaccucccc cugcugcauc gucaccagca     1860

ccuacggcug gacggccaac auggagcgga ucaugaaggc ccaggcccug cgcgacaacu     1920

ccaccauggg guacauggcc gcgaagaagc accuggagau caaccccgac cacagcauca     1980

ucgagacccu gcggcagaag gccgaggccg acaagaacga caaguccgug aaggaccucg     2040

ugauccugcu guacgagacc gcccuccuga gcuccggcuu cagccuggag gacccgcaga     2100

cgcacgccaa ccgcaucuac cggaugauca agcucgggcu gggcaucgac gaggacgacc     2160

ccaccgcgga cgacaccucc gccgccguca ccgaggagau gccgccccug gagggggacg     2220

acgacaccag ccgcauggag gagguggacu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  2755
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt1)

<400>  2755
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcuccaagcu ggacagcggc aaggggcucc acaucaaccu ggugcccaac aagcagaacc      120

agacccugac caucgucgac acgcgcaucg gcaugaccaa gaccgaccuc aucaacaacc      180

uggggaccgu gacgaagucc ggcaccaagg ccuucaugga ggcccugcag gcggacgccg      240

acaucagcau gaucgggcac uucggcgugg gcuucuacuc cgccuaccuc gucgccaaga      300

aggugaccgu gaucagcaag cacaacaacg acgagcagua caccugggag uccagcgccg      360

ggggcuccuu cacgguccgg accgacgagu gaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  2756
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt1)

<400>  2756
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggaggugca ccacggcgag gaggaggucg agaccuucgc cuuccaggcc gagaucgcgc      120

agcugaugag ccucaucauc aacaccuucu acuccaacaa ggagaucuuc cugcgcgagc      180

ugaucagcaa cgccuccgac gcccucgaca agauccggua cgagagccug acggacccgu      240

ccaagcugga cagcgggaag gagcucaaga ucgacaucau ccccaacccc caggagcgca      300

cccugacccu gguggacacc ggcaucggga ugacgaaggc cgaccucauc aacaaccugg      360

gcaccaucgc caaguccggg accaaggcgu ucauggaggc ccugcaggcc ggcgccgaca      420

ucagcaugau cggccaguuc ggggugggcu ucuacuccgc guaccucguc gccgagaagg      480

ugguggucau caccaagcac aacgacgacg agcaguacgc cugggagagc uccgccgggg      540

gcagcuucac ggugcgggcc gaccacgggg agcccaucgg ccgcggcacc aaggugaucc      600

ugcaccugaa ggaggaccag accgaguacc ucgaggagcg gcgcgucaag gaggugguga      660

agaagcacuc ccaguucauc ggguacccga ucacccugua ccuggagaag gagcgggaga      720

aggagaucag cgacgacgag gcggaggagg agaagggcga gaaggaggag gaggacaagg      780

acgacgagga gaagcccaag aucgaggacg ucggguccga cgaggaggac gacagcggca      840

aggacaagaa gaagaagacg aagaagauca aggagaagua caucgaccag gaggagcuca      900

acaagaccaa gcccaucugg acccgcaacc ccgacgacau cacccaggag gaguacggcg      960

aguucuacaa gucccugacg aacgacuggg aggaccaccu ggccgugaag cacuucagcg     1020

uggaggggca gcucgaguuc cgggcccugc uguucauccc gcgccgggcc cccuucgacc     1080

ucuucgagaa caagaagaag aagaacaaca ucaagcugua cguccgccgg guguucauca     1140

uggacuccug cgacgagcug auccccgagu accucaacuu cauccgcggc guggucgaca     1200

gcgaggaccu gccccugaac aucagccggg agaugcucca gcaguccaag auccugaagg     1260

ugauccgcaa gaacaucgug aagaagugcc uggagcuguu cagcgagcuc gccgaggaca     1320

aggagaacua caagaaguuc uacgaggcgu ucuccaagaa ccugaagcuc gggauccacg     1380

aggacagcac caaccggcgc cggcuguccg agcugcuccg cuaccacacc agccaguccg     1440

gcgacgagau gaccagccug uccgaguacg ucagccggau gaaggagacg cagaagucca     1500

ucuacuacau caccggggag agcaaggagc aggucgccaa cuccgccuuc guggagcgcg     1560

ugcgcaagcg gggcuucgag guggucuaca ugaccgagcc gaucgacgag uacugcgugc     1620

agcagcugaa ggaguucgac ggcaagagcc ucguguccgu caccaaggag gggcuggagc     1680

ugcccgagga cgaggaggag aagaagaaga uggaggagag caaggccaag uucgagaacc     1740

ucugcaagcu gaugaaggag auccuggaca agaaggugga gaaggugacg aucuccaacc     1800

gccucgucag cucccccugc ugcaucguga ccagcaccua cggcuggacc gccaacaugg     1860

agcggaucau gaaggcgcag gcccugcgcg acaacagcac gaugggguac augauggcca     1920

agaagcaccu ggagaucaac cccgaccacc cgaucgugga gacccugcgg cagaaggccg     1980

aggccgacaa gaacgacaag gcggucaagg accucguggu gcugcuguuc gagaccgccc     2040

uccuguccag cggcuucucc cuggaggacc cccagaccca cagcaaccgc aucuaccgga     2100

ugaucaagcu cgggcugggc aucgacgagg acgaggucgc cgccgaggag cccaacgcgg     2160

ccgugcccga cgagaucccg ccccuggagg gcgacgagga cgccucccgc auggaggagg     2220

uggacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  2757
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt1)

<400>  2757
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcgcg       60

cccugugggu gcucggccug ugcugcgucc ugcucaccuu cgggagcgug cgggccgacg      120

acgaggugga cgucgacggc accguggagg aggaccuggg gaagucccgc gagggcagcc      180

ggacggacga cgaggugguc cagcgcgagg aggaggcgau ccagcuggac gggcucaacg      240

ccucccagau ccgggagcug cgcgagaagu ccgagaaguu cgccuuccag gccgagguga      300

accggaugau gaagcugauc aucaacagcc ucuacaagaa caaggagauc uuccugcgcg      360

agcugaucag caacgccucc gacgcgcucg acaagauccg gcugaucagc cugaccgacg      420

agaacgcccu cuccggcaac gaggagcuga ccgugaagau caagugcgac aaggagaaga      480

accugcucca cgucaccgac acgggcgugg ggaugacccg cgaggagcug gugaagaacc      540

ugggcaccau cgccaagagc gggaccuccg aguuccucaa caagaugacg gaggcccagg      600

aggacggcca gagcaccucc gagcugaucg ggcaguucgg cgucggcuuc uacagcgcgu      660

uccugguggc cgacaaggug aucgucaccu ccaagcacaa caacgacacc cagcacaucu      720

gggagagcga cuccaacgag uucagcguga ucgccgaccc ccgggggaac acgcucggcc      780

gcgggaccac caucacccug gugcugaagg aggaggccuc cgacuaccuc gagcuggaca      840

cgaucaagaa ccuggucaag aaguacagcc aguucaucaa cuucccgauc uacgugugga      900

gcuccaagac cgagaccgug gaggagccca uggaggagga ggaggccgcg aaggaggaga      960

aggaggagag cgacgacgag gccgccgucg aggaggagga ggaggagaag aagcccaaga     1020

ccaagaaggu ggagaagacg gugugggacu gggagcucau gaacgacauc aagcccaucu     1080

ggcagcggcc guccaaggag gucgaggagg acgaguacaa ggccuucuac aagagcuucu     1140

ccaaggagag cgacgacccc auggccuaca uccacuucac cgcggagggc gaggugaccu     1200

ucaaguccau ccuguucguc cccaccagcg cgccccgcgg ccuguucgac gaguacgggu     1260

ccaagaaguc cgacuacauc aagcucuacg ugcggcgcgu guucaucacg gacgacuucc     1320

acgacaugau gccgaaguac cugaacuucg ucaagggcgu gguggacagc gacgaccugc     1380

cccucaacgu cagccgggag acccugcagc agcacaagcu gcucaaggug auccgcaaga     1440

agcuggugcg gaagacccug gacaugauca agaagaucgc cgacgacaag uacaacgaca     1500

ccuucuggaa ggaguucggg acgaacauca agcucggcgu caucgaggac cacuccaacc     1560

gcacccggcu ggccaagcug cuccgcuucc agagcuccca ccaccccacc gacaucacca     1620

gccuggacca guacguggag cgcaugaagg agaagcagga caagaucuac uucauggccg     1680

gguccagccg gaaggaggcc gaguccagcc ccuucgugga gcgccugcuc aagaagggcu     1740

acgaggucau cuaccugacg gagccggugg acgaguacug cauccaggcc cugcccgagu     1800

ucgacggcaa gcgguuccag aacguggcca aggagggggu caaguucgac gagagcgaga     1860

agaccaagga gucccgcgag gccguggaga aggaguucga gccccugcuc aacuggauga     1920

aggacaaggc ccugaaggac aagaucgaga aggcgguggu cagccagcgg cugaccgagu     1980

cccccugcgc ccucguggcc agccaguacg gcugguccgg gaacauggag cgcaucauga     2040

aggcccaggc guaccagacc ggcaaggaca ucagcacgaa cuacuacgcc ucccagaaga     2100

agaccuucga gaucaacccg cggcaccccc ugauccgcga caugcugcgg cgcaucaagg     2160

aggacgagga cgacaagacc gugcucgacc uggccgucgu gcuguucgag accgccaccc     2220

uccggagcgg guaccugcug cccgacacga aggccuacgg cgaccgcauc gagcggaugc     2280

uccgccuguc ccugaacauc gaccccgacg cgaaggugga ggaggagccg gaggaggagc     2340

ccgaggagac cgccgaggac accaccgagg acacggagca ggacgaggac gaggagaugg     2400

acgucggcac cgacgaggag gaggagaccg ccaaggagag caccgccgag aaggacgagc     2460

ucugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  2758
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt1)

<400>  2758
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

gcgagcugcg ggcccuccug cuguggggcc gccggcuccg cccccugcug cgggcgccgg      120

cccucgccgc cgugcccggg ggcaagccca uccugugccc ccgccggacc accgcccagc      180

uggggccgcg ccggaacccc gcguggagcc uccaggccgg ccgccuguuc uccacgcaga      240

ccgccgagga caaggaggag ccccugcaca gcaucaucuc cagcaccgag uccguccagg      300

ggagcaccuc caagcacgag uuccaggccg agacgaagaa gcuccuggac aucguggcgc      360

ggagccugua cuccgagaag gagguguuca uccgcgagcu caucagcaac gccuccgacg      420

cccuggagaa gcugcggcac aagcucguca gcgacggcca ggcccugccc gagauggaga      480

uccaccucca gaccaacgcc gagaagggca ccaucaccau ccaggacacg gggaucggca      540

ugacccagga ggagcuggug uccaaccugg ggaccaucgc gcgcagcggc uccaaggccu      600

uccuggacgc ccuccagaac caggccgagg ccagcuccaa gaucaucggg caguucggcg      660

ugggcuucua cagcgcguuc auggucgccg accgggugga gguguacucc cgcagcgccg      720

ccccggggag ccugggcuac caguggcugu ccgacgggag cggcgucuuc gagaucgccg      780

aggcguccgg cgugcggacc gggacgaaga ucaucaucca ccucaagagc gacugcaagg      840

aguucuccag cgaggcccgc gugcgggacg ucgugaccaa guacuccaac uucgugagcu      900

ucccccugua ccugaacggc cgccggauga acacccucca ggccaucugg augauggacc      960

ccaaggacgu ccgcgagugg cagcacgagg aguucuaccg cuacguggcc caggcccacg     1020

acaagccccg guacacccug cacuacaaga cggacgcgcc gcugaacauc cgcuccaucu     1080

ucuacgugcc cgacaugaag cccagcaugu ucgacgucuc ccgggagcuc gggagcuccg     1140

uggcccugua cagccgcaag gugcugaucc agaccaaggc caccgacauc cuccccaagu     1200

ggcugcgguu cauccgcggc gucguggacu ccgaggacau cccgcugaac cucagccggg     1260

agcugcugca ggaguccgcc cucauccgca agcugcggga cgugcugcag cagcgccuca     1320

ucaaguucuu caucgaccag agcaagaagg acgcggagaa guacgccaag uucuucgagg     1380

acuacgggcu guucaugcgg gagggcaucg ucaccgccac ggagcaggag gugaaggagg     1440

acaucgccaa gcugcuccgc uacgagucca gcgcccugcc cagcggccag cugaccuccc     1500

ugagcgagua cgcgucccgg augcgcgccg ggacccggaa caucuacuac cucugcgccc     1560

ccaaccgcca ccuggccgag cacagccccu acuacgaggc caugaagaag aaggacaccg     1620

agguccuguu cugcuucgag caguucgacg agcucacgcu gcugcaccuc cgggaguucg     1680

acaagaagaa gcugaucucc guggagaccg acaucguggu cgaccacuac aaggaggaga     1740

aguucgagga ccgcagcccg gcggccgagu gccuguccga gaaggagacc gaggagcuca     1800

uggccuggau gcggaacgug cugggcagcc gcgugaccaa cgucaaggug acgcugcgcc     1860

ucgacaccca ccccgccaug gugaccgucc uggagauggg ggccgcgcgg cacuuccugc     1920

gcaugcagca gcucgccaag acccaggagg agcgggccca gcugcugcag cccacgcucg     1980

agaucaaccc ccgccacgcc cugaucaaga agcugaacca gcuccgggcg uccgagccgg     2040

gccuggccca gcugcucgug gaccagaucu acgagaacgc caugaucgcc gccgggcugg     2100

uggacgaccc ccgcgcgaug gucggccggc ugaacgagcu ccuggugaag gcccuggagc     2160

gccacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  2759
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt1)

<400>  2759
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

agaucagcuc ccugcccacc cagcuguuca agugcugcuu cugcgacuuc cucaagguga      120

agaugcacac caugagcucc agccaccugu ucuaccucgc ccugugccug cucacguuca      180

ccuccagcgc caccgcgggg ccggagaccc ugugcggcgc cgagcugguc gacgcccucc      240

aguucgugug cggggaccgc ggcuucuacu ucaacaagcc cacgggguac ggcuccagcu      300

cccggcgcgc gccccagacc ggcaucgugg acgagugcug cuuccggagc ugcgaccugc      360

gccggcugga gauguacugc gcgccccuca agccggccaa guccgcccgc agcguccggg      420

cccagcgcca caccgacaug cccaagaccc agaaggaggu gcaccugaag aacgccuccc      480

gggggagcgc cggcaacaag aacuaccgca ugugaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  2760
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt1)

<400>  2760
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

uccccauggg gaaguccaug cuggugcucc ugaccuuccu ggccuucgcc agcugcugca      120

ucgcggccua ccgcccgagc gagacccucu gcggcgggga gcuggucgac acgcugcagu      180

ucgugugcgg cgaccggggg uucuacuucu cccgccccgc cagccgggug ucccgccgga      240

gccgcggcau cgucgaggag ugcugcuucc gguccugcga ccucgcccug cuggagaccu      300

acugcgccac ccccgccaag agcgagcgcg acguguccac gcccccgacc gugcuccccg      360

acaacuuccc ccgguacccc gucggcaagu ucuuccagua cgacaccugg aagcagagca      420

cccagcgccu gcggcgcggg cugccggcgc uccugcgggc ccgccggggc cacgugcugg      480

ccaaggagcu cgaggcguuc cgcgaggcca agcggcaccg cccccugauc gcccugccca      540

cccaggaccc cgcccacggg ggcgccccgc ccgagauggc guccaaccgg aagugaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  2761
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt1)

<400>  2761
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaca       60

gcuucuccac cagcgccuuc ggccccgugg ccuucucccu ggggcuccug cugguccucc      120

cggcggccuu ccccgccccc gugcccccgg gcgaggacag caaggacgug gccgcgcccc      180

accgccagcc ccugaccucc agcgagcgga ucgacaagca gauccgcuac auccuggacg      240

ggaucuccgc ccuccggaag gagacgugca acaagagcaa caugugcgag uccagcaagg      300

aggcccuggc cgagaacaac cugaaccucc ccaagauggc cgagaaggac ggcugcuucc      360

aguccggguu caacgaggag accugccugg ucaagaucau caccggccug cucgaguucg      420

agguguaccu ggaguaccug cagaaccgcu ucgagagcuc cgaggagcag gcgcgggccg      480

ugcagaugag caccaagguc cucauccagu uccugcagaa gaaggccaag aaccuggacg      540

ccaucacgac cccggacccc accaccaacg ccucccuccu gacgaagcug caggcgcaga      600

accaguggcu ccaggacaug accacccacc ugauccugcg cagcuucaag gaguuccucc      660

aguccagccu gcgggcccug cgccagaugu gaggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  2762
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt1)

<400>  2762
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugcucuggcu gcgcggcuuc cugcucgcca gcugcuggau caucgugcgg uccagcccga      120

cccccggguc cgagggccac agcgccgcgc ccgacugccc cuccugcgcc cuggccgccc      180

ugccgaagga cguccccaac agccagcccg agauggugga ggccgugaag aagcacaucc      240

ucaacaugcu gcaccugaag aagcgccccg acgucaccca gccggugccc aaggcggccc      300

uccugaacgc cauccggaag cugcacgugg ggaaggucgg cgagaacggg uacguggaga      360

ucgaggacga caucggccgc cgggccgaga ugaacgagcu cauggagcag acguccgaga      420

ucaucaccuu cgcggagagc ggcaccgccc gcaagacccu gcacuucgag aucuccaagg      480

aggggagcga ccuguccgug gucgagcggg ccgaggugug gcuguuccuc aaggugccca      540

aggccaaccg cacgcggacc aaggucacca uccgccuguu ccagcagcag aagcaccccc      600

agggcagccu cgacaccggg gaggaggccg aggagguggg ccugaagggg gagcgguccg      660

agcugcuccu gagcgagaag guggucgacg cgcgcaaguc cacguggcac guguucccgg      720

ugagcuccag cauccagcgg cugcucgacc agggcaaguc cagccuggac guccgcaucg      780

ccugcgagca gugccaggag agcggcgccu cccuggugcu ccuggggaag aagaagaaga      840

aggaggagga gggcgagggg aagaagaagg gcggcgggga gggcggggcc ggcgccgacg      900

aggagaagga gcagagccac cggcccuucc ugaugcucca ggcgcgccag uccgaggacc      960

acccccaccg gcgccggcgc cgggggcugg agugcgacgg caaggugaac aucugcugca     1020

agaagcaguu cuucgucagc uucaaggaca ucggcuggaa cgacuggauc aucgcccccu     1080

ccggguacca cgccaacuac ugcgagggcg agugcccgag ccacaucgcc gggaccuccg     1140

gcagcucccu gagcuuccac uccaccguga ucaaccacua ccgcaugcgc gggcacagcc     1200

ccuucgccaa ccucaagucc ugcugcgugc ccaccaagcu gcggcccaug agcaugcugu     1260

acuacgacga cggccagaac aucaucaaga aggacaucca gaacaugauc gucgaggagu     1320

gcggcugcuc cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  2763
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt1)

<400>  2763
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacg       60

gccugcccgg gcgcgcccuc ggcgccgcgu gccugcugcu ccuggccgcc ggguggcugg      120

gcccggaggc cugggggagc cccaccccgc ccccgacccc cgccgcgccc ccgcccccgc      180

ccccgcccgg cucccccggc gggagccagg acacgugcac cuccugcggc ggguuccggc      240

gccccgagga gcucggccgg guggacgggg acuuccugga ggccgucaag cgccacaucc      300

ugagccggcu ccagaugcgc ggccggccca acaucaccca cgccgugccc aaggccgcga      360

uggugaccgc ccugcgcaag cugcacgccg gcaagguccg ggaggacggg cgcguggaga      420

ucccccaccu cgacggccac gccucccccg gggccgacgg ccaggagcgg gugagcgaga      480

ucaucuccuu cgcggagacg gacggccugg ccagcucccg cguccggcug uacuucuuca      540

ucagcaacga ggggaaccag aaccucuucg uggugcaggc cucccugugg cuguaccuca      600

agcugcugcc cuacguccuc gagaagggca gccgccggaa ggugcgcgug aaggucuacu      660

uccaggagca ggggcacggc gaccggugga acauggugga gaagcgcgug gaccugaagc      720

gguccgggug gcacaccuuc ccccugaccg aggccaucca ggcccucuuc gagcgcggcg      780

agcggcgccu gaaccuggac guccagugcg acagcugcca ggagcucgcg guggugcccg      840

ucuucgugga ccccggcgag gagucccacc gccccuucgu ggucgugcag gcccggcugg      900

gggacagccg ccaccggauc cgcaagcggg gccuggagug cgacgggcgc accaaccucu      960

gcugccggca gcaguucuuc aucgacuucc gccugaucgg cuggaacgac uggaucaucg     1020

ccccgacggg guacuacggc aacuacugcg agggcuccug ccccgccuac cuggccgggg     1080

ugcccggcag cgcguccagc uuccacaccg ccgucgugaa ccaguaccgg augcgcgggc     1140

ucaaccccgg caccgucaac agcugcugca ucccgaccaa gcuguccacg augagcaugc     1200

uguacuucga cgacgaguac aacaucguga agcgggacgu gcccaacaug aucgucgagg     1260

agugcgggug cgccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  2764
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt1)

<400>  2764
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ugcgcgugcu ccugcugacc gcccucaccc ugugccacgg cuucaaccug gacacggaga      120

acgcgaugac cuuccaggag aacgcccggg gguucggcca gagcgucgug cagcuccagg      180

ggucccgcgu ggucgugggc gccccccagg agaucguggc cgccaaccag cgggggagcc      240

uguaccagug cgacuacucc accggcagcu gcgagccgau ccgccugcag guccccgugg      300

aggcggugaa caugucccuc ggccugagcc uggccgccac cacguccccc ccccagcucc      360

uggccugcgg gccgaccguc caccagaccu gcagcgagaa caccuacgug aagggccugu      420

gcuuccucuu cggguccaac cugcggcagc agccccagaa guuccccgag gcgcugcgcg      480

gcugccccca ggaggacagc gacaucgccu uccucaucga cggguccggc agcaucaucc      540

cgcacgacuu ccggcgcaug aaggaguucg uguccacggu cauggagcag cugaagaagu      600

ccaagacccu guucucccuc augcaguaca gcgaggaguu ccggauccac uucaccuuca      660

aggaguucca gaacaacccc aacccccgcu cccuggugaa gcccaucacc cagcugcucg      720

gccggacgca caccgccacc gggauccgca aggugguccg ggagcuguuc aacaucacca      780

acggcgcccg caagaacgcc uucaagaucc ugguggugau cacggacggg gagaaguucg      840

gcgacccgcu cggcuacgag gacgucaucc ccgaggcgga ccgggagggg gugauccgcu      900

acgugaucgg cgucggggac gccuuccgga gcgagaaguc ccgccaggag cugaacacca      960

ucgccagcaa gcccccccgg gaccacgugu uccaggugaa caacuucgag gcccugaaga     1020

ccauccagaa ccagcuccgc gagaagaucu ucgccaucga gggcacccag acggggagcu     1080

ccagcuccuu cgagcacgag augagccagg agggcuucuc cgcggccauc accagcaacg     1140

gcccgcugcu guccaccguc gggagcuacg acugggccgg cgggguguuc cucuacaccu     1200

ccaaggagaa guccacguuc aucaacauga cccgggucga cuccgacaug aacgacgccu     1260

accugggcua cgccgcggcc aucauccugc gcaaccgcgu gcagagccuc gugcuggggg     1320

ccccccggua ccagcacauc ggccuggucg ccauguuccg ccagaacacc ggcauguggg     1380

aguccaacgc caacgugaag gggacccaga ucggcgcgua cuucggggcc agccucugcu     1440

ccguggacgu cgacagcaac ggcuccacgg accuggugcu gaucggggcc ccccacuacu     1500

acgagcagac ccggggcggc caggugagcg ucugcccccu cccgcgcggg cgggcccgcu     1560

ggcagugcga cgcggugcug uacggcgagc aggggcagcc cuggggccgg uucggcgccg     1620

cccugaccgu gcucggggac gucaacggcg acaagcugac cgacguggcc aucggggccc     1680

ccggcgagga ggacaaccgc ggggcggugu accuguucca cggcacgucc ggcagcggga     1740

ucagccccuc ccacagccag cggaucgccg gcuccaagcu cagcccgcgc cugcaguacu     1800

ucgggcaguc ccugagcggc gggcaggacc ugaccaugga cggccucguc gaccugaccg     1860

ugggcgccca ggggcacgug cugcuccugc ggucccagcc cguccugcgc gugaaggcca     1920

ucauggaguu caacccccgg gagguggccc gcaacgucuu cgagugcaac gaccaggugg     1980

ugaagggcaa ggaggcgggg gagguccggg ugugccucca cgugcagaag uccacccgcg     2040

accggcugcg cgagggccag auccaguccg ucgugacgua cgaccuggcc cucgacagcg     2100

ggcggcccca cucccgcgcc guguucaacg agaccaagaa cagcacccgc cggcagaccc     2160

agguccuggg ccugacccag acgugcgaga cccucaagcu gcagcugccg aacugcaucg     2220

aggaccccgu gucccccauc gugcuccgcc ugaacuucag ccuggucggc accccgcucu     2280

ccgccuucgg gaaccugcgg cccgugcugg ccgaggacgc gcagcgccuc uucaccgccc     2340

uguuccccuu cgagaagaac ugcggcaacg acaacaucug ccaggacgac cugagcauca     2400

cguucuccuu caugagccuc gacugccugg uggucggggg cccccgggag uucaacguga     2460

ccgugaccgu ccgcaacgac ggggaggaca gcuaccggac ccaggugacg uucuucuucc     2520

cgcuggaccu cuccuaccgc aaggugagca cccugcagaa ccagcggucc cagcgcagcu     2580

ggcggcuggc cugcgagucc gccagcucca ccgaggucag cggcgcgcuc aaguccacca     2640

gcugcuccau caaccacccc aucuuccccg agaacagcga ggugacguuc aacaucaccu     2700

ucgacgugga cuccaaggcc agccugggca acaagcugcu ccugaaggcc aacgucaccu     2760

ccgagaacaa caugccccgc accaacaaga cggaguucca gcuggagcuc ccggugaagu     2820

acgccgugua cauggucgug accagccacg ggguguccac caaguaccug aacuucaccg     2880

ccagcgagaa cacgucccgg gucaugcagc accaguacca ggugagcaac cugggccagc     2940

gcagccuccc caucucccug gucuuccugg ugcccgugcg gcucaaccag accgucaucu     3000

gggaccgccc ccaggugacc uucagcgaga accuguccag cacaugccac acgaaggagc     3060

ggcugccguc ccacagcgac uuccucgcgg agcugcgcaa ggcccccgug gucaacugcu     3120

ccaucgccgu gugccagcgg auccagugcg acauccccuu cuucgggauc caggaggagu     3180

ucaacgccac ccugaagggc aaccucagcu ucgacuggua caucaagacc ucccacaacc     3240

accuccugau cgugagcacc gccgagaucc ucuucaacga cuccgucuuc acgcugcugc     3300

ccggccaggg ggcguucgug cgcagccaga ccgagaccaa gguggagccg uucgaggucc     3360

ccaacccccu cccccugauc gugggcucca gcgugggggg ccugcuccug cuggcccuca     3420

ucaccgccgc ccuguacaag cugggguucu ucaagcggca guacaaggac augauguccg     3480

agggcggccc gcccggggcc gagccccagu gaggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  2765
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt1)

<400>  2765
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguuca       60

gccugaagac ccuccccuuc cugcugcucc ugcacgugca gaucuccaag gccuucccgg      120

ucagcuccaa ggagaagaac accaagacgg ugcaggacua ccuggagaag uucuaccagc      180

uccccagcaa ccaguaccag uccacccgca agaacggcac caacgugauc gucgagaagc      240

ugaaggagau gcagcgguuc uucgggcuga acgugaccgg caagcccaac gaggagacgc      300

ucgacaugau gaagaagccc cgcugcgggg ugccggacag cggcggguuc augcugaccc      360

ccggcaaccc caagugggag cggaccaacc ugaccuaccg cauccggaac uacacgcccc      420

agcucuccga ggccgagguc gagcgcgcga ucaaggacgc cuucgagcug uggagcgugg      480

ccuccccgcu gaucuucacc cggaucagcc agggcgaggc cgacaucaac aucgccuucu      540

accagcgcga ccacggggac aacucccccu ucgacggccc caacgggauc cucgcgcacg      600

ccuuccagcc cggccagggg aucggcggcg acgcccacuu cgacgccgag gagaccugga      660

ccaacacgag cgcgaacuac aaccuguucc ugguggccgc ccacgaguuc gggcacuccc      720

ucggccuggc ccacagcucc gacccggggg cccugaugua ccccaacuac gcguuccggg      780

agaccagcaa cuacucccuc ccccaggacg acaucgacgg cauccaggcc aucuacggcc      840

ugagcuccaa ccccauccag ccgaccgggc ccagcacccc caagcccugc gacccgagcc      900

ugacguucga cgccaucacc acccuccgcg gcgagauccu guucuucaag gaccgguacu      960

ucuggcgccg gcacccccag cugcagcgcg ucgagaugaa cuucaucucc cucuucuggc     1020

ccagccugcc caccgggauc caggccgccu acgaggacuu cgaccgggac cugaucuucc     1080

ucuucaaggg caaccaguac ugggcgcugu ccggguacga cauccugcag ggcuacccga     1140

aggacaucag caacuacggc uuccccucca gcgugcaggc caucgacgcc gccguguucu     1200

accgcuccaa gacguacuuc uucgucaacg accaguucug gcgguacgac aaccagcgcc     1260

aguucaugga gcccggguac cccaagagca ucuccggcgc cuucccgggg aucgagagca     1320

agguggacgc gguguuccag caggagcacu ucuuccacgu cuucuccggc ccccgguacu     1380

acgccuucga ccucaucgcc cagcgcguga cccggguggc ccgcgggaac aaguggcuga     1440

acugccgcua cggcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  2766
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt1)

<400>  2766
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

uguggcagcc ccucgugcug guccugcucg ugcugggcug cugcuucgcc gccccgcgcc      120

agcggcaguc cacccugguc cucuuccccg gggaccugcg caccaaccug acggaccggc      180

agcucgcgga ggaguaccug uaccgcuacg gcuacacccg gguggccgag augcgcgggg      240

agagcaaguc ccugggcccc gcccuccugc ugcuccagaa gcagcugagc cugcccgaga      300

ccggggagcu cgacuccgcc acccugaagg ccaugcggac gccgcgcugc ggcgugcccg      360

accugggccg guuccagacc uucgaggggg accucaagug gcaccaccac aacaucaccu      420

acuggaucca gaacuacagc gaggaccugc cccgcgcggu gaucgacgac gccuucgccc      480

gggccuucgc gcuguggucc gccgucacgc cccucaccuu cacccgcgug uacagccggg      540

acgccgacau cgugauccag uucggcgucg ccgagcacgg ggacggcuac ccguucgacg      600

ggaaggacgg ccugcuggcc cacgcguucc cgcccggccc cgggauccag ggcgacgccc      660

acuucgacga cgacgagcuc uggucccugg ggaagggcgu gguggucccc acccgcuucg      720

gcaacgccga cggggccgcc ugccacuucc ccuucaucuu cgagggccgg agcuacuccg      780

cgugcaccac ggacgggcgc agcgacggcc ugcccuggug cuccaccacc gccaacuacg      840

acaccgacga ccgguucggg uucugcccca gcgagcgccu cuacacgcag gacggcaacg      900

ccgacggcaa gccgugccag uuccccuuca ucuuccaggg gcaguccuac agcgccugca      960

ccaccgacgg ccgguccgac ggguaccgcu ggugcgccac cacggcgaac uacgaccggg     1020

acaagcuguu cggcuucugc cccacccgcg ccgacagcac cgugaugggc ggcaacuccg     1080

ccggcgagcu gugcguguuc cccuucaccu uccucgggaa ggaguacagc acgugcacca     1140

gcgagggccg cggggacggc cggcuguggu gcgccaccac cuccaacuuc gacagcgaca     1200

agaagugggg guucugcccg gaccagggcu acucccuguu ccucgucgcc gcgcacgagu     1260

ucggccacgc ccuggggcug gaccacagcu ccgugcccga ggcccucaug uaccccaugu     1320

accgcuucac ggaggggccc ccgcugcaca aggacgacgu gaacgggauc cggcaccugu     1380

acggcccccg ccccgagccc gagccgcggc cgcccaccac caccacgccc cagcccaccg     1440

ccccgcccac cgucugcccc accggcccgc ccacggugca ccccagcgag cgccccaccg     1500

cggggcccac cggcccgccc uccgccgggc ccaccggccc gcccaccgcc gggcccagca     1560

cggccaccac cgugccccuc ucccccgucg acgacgccug caacgugaac aucuucgacg     1620

cgaucgccga gaucggcaac cagcuguacc uguucaagga cggcaaguac uggcgguuca     1680

gcgaggggcg cggcucccgg ccccaggggc ccuuccucau cgccgacaag uggccggccc     1740

ugccccgcaa gcuggacagc guguucgagg agcggcucuc caagaagcug uucuucuuca     1800

gcggccgcca ggucugggug uacaccgggg ccuccguccu gggcccccgg cgccuggaca     1860

agcucggccu gggggcggac guggcccagg ugacgggcgc ccugcggagc gggcgcggca     1920

agaugcuccu guucuccggg cggcgccugu ggcgguucga cgucaaggcc cagauggugg     1980

acccccgcag cgccuccgag guggaccgca uguucccggg cgucccccuc gacacccacg     2040

acguguucca guaccgggag aaggcguacu ucugccagga ccgcuucuac uggcggguga     2100

gcagccgcuc cgagcugaac caggucgacc aggugggcua cgugaccuac gacauccugc     2160

agugccccga ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  2767
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt1)

<400>  2767
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ccggcgugcu ggccgccuuc cucuuccuga gcuggaccca cugccgcgcg cugccgcucc      120

ccuccggggg cgacgaggac gaccugagcg aggaggaccu gcaguucgcc gagcgguacc      180

uccgcuccua cuaccacccc accaaccugg ccgggauccu gaaggagaac gccgccagcu      240

ccaugacgga gcggcuccgc gagaugcaga gcuucuucgg ccuggagguc accgggaagc      300

uggacgacaa cacccucgac gugaugaaga agccccggug cggcgugccg gacgucggcg      360

aguacaacgu guucccccgc acccugaagu gguccaagau gaaccugacg uaccggaucg      420

ugaacuacac ccccgacaug acccacagcg aggucgagaa ggcguucaag aaggccuuca      480

aggugugguc cgacgugacg ccccucaacu ucacccgccu gcacgacggg aucgccgaca      540

ucaugaucag cuucggcauc aaggagcacg gggacuucua cccguucgac ggccccuccg      600

ggcugcucgc ccacgcguuc ccgcccggcc ccaacuacgg cggggacgcc cacuucgacg      660

acgacgagac cuggaccagc uccagcaagg gcuacaaccu guuccugguc gccgcccacg      720

aguucgggca cucccucggc cuggaccaca gcaaggaccc cggcgcccug auguucccca      780

ucuacaccua cacggggaag ucccacuuca ugcuccccga cgacgacgug cagggcaucc      840

agagccugua cgggccgggc gacgaggacc ccaaccccaa gcaccccaag accccggaca      900

agugcgaccc cucccugagc cucgacgcga ucaccagccu gcgcggggag accaugaucu      960

ucaaggaccg guucuucugg cggcugcacc cccagcaggu cgacgccgag cuguuccuga     1020

cgaaguccuu cuggcccgag cugccgaacc gcaucgacgc cgccuacgag caccccagcc     1080

acgaccucau cuucaucuuc cggggccgca aguucugggc ccugaacggc uacgacaucc     1140

uggaggggua ccccaagaag aucuccgagc ucggccugcc caaggaggug aagaagauca     1200

gcgcggccgu gcacuucgag gacaccggga agacccuccu cuucuccggc aaccaggugu     1260

ggcgguacga cgacaccaac cacaucaugg acaaggacua cccgcgccug aucgaggagg     1320

acuuccccgg gaucggcgac aaggucgacg ccguguacga gaagaacggc uacaucuacu     1380

ucuucaacgg gcccauccag uucgaguaca gcaucugguc caaccggauc gugcgcguca     1440

ugccggccaa cagcauccug uggugcugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  2768
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt1)

<400>  2768
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

cccccaacac cacggaggac uacgacacca ccaccgaguu cgacuacggc gacgccacgc      120

cgugccagaa ggugaacgag cgcgccuucg gggcgcagcu gcucccgccc cuguacagcc      180

uggucuucgu gaucggccuc guggggaaca uccuggucgu gcuggugcuc guccaguaca      240

agcggcugaa gaacaugacc uccaucuacc ugcucaaccu ggccaucagc gaccuccucu      300

uccuguucac ccugcccuuc uggaucgacu acaagcucaa ggacgacugg guguucggcg      360

acgccaugug caagauccug uccggguucu acuacaccgg ccuguacagc gagaucuucu      420

ucaucauccu ccugacgauc gaccgcuacc uggccaucgu gcacgccguc uucgcgcucc      480

gggcccgcac cgugaccuuc ggcgugauca ccuccaucau caucugggcc cuggccaucc      540

uggcgagcau gcccgggcuc uacuucucca agacgcagug ggaguucacc caccacacgu      600

gcagccugca cuucccccac gagucccugc gggaguggaa gcuguuccag gcccugaagc      660

ugaaccucuu cggccugguc cugccccucc uggugaugau caucugcuac accgggauca      720

ucaagauccu gcuccgccgg cccaacgaga agaaguccaa ggccgugcgc cugaucuucg      780

ucaucaugau caucuucuuc cuguucugga ccccguacaa ccucaccauc cugaucagcg      840

uguuccagga cuuccuguuc acccacgagu gcgagcagag ccggcaccuc gaccuggccg      900

ugcaggucac cgaggugauc gccuacacgc acugcugcgu gaaccccguc aucuacgcgu      960

ucgugggcga gcgcuuccgg aaguaccugc gccagcuguu ccaccggcgc guggccgucc     1020

accucgugaa guggcugccc uuccucuccg ucgaccggcu ggagcgcgug agcuccacca     1080

gccccuccac cggggagcac gagcugagcg ccggcuucug aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  2769
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt1)

<400>  2769
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcgca       60

cccuggccug ccuccugcug cucggcugcg gguaccuggc ccacgugcug gcggaggagg      120

ccgagauccc ccgggaggug aucgagcgcc ucgcccggag ccagauccac uccauccgcg      180

accugcagcg gcugcucgag aucgacagcg ugggcuccga ggacagccug gacaccuccc      240

ugcgcgccca cggggugcac gccacgaagc acgucccgga gaagcggccc cuccccaucc      300

gccggaagcg cagcaucgag gaggcggugc ccgccgugug caagacccgg accgucaucu      360

acgagauccc gcgcucccag guggacccca ccagcgccaa cuuccugauc uggccgcccu      420

gcguggaggu caagcggugc acgggcugcu gcaacaccuc cagcgugaag ugccagcccu      480

cccgcgugca ccaccggagc gucaaggugg ccaaggugga guacguccgc aagaagccca      540

agcugaagga gguccaggug cggcucgagg agcaccugga gugcgcgugc gccaccaccu      600

cccugaaccc cgacuaccgc gaggaggaca cggggcggcc ccgcgagagc ggcaagaagc      660

ggaagcgcaa gcgccucaag ccgaccugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  2770
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt1)

<400>  2770
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacc       60

gcugcugggc ccuguuccuc agccugugcu gcuaccugcg gcucgugucc gccgagggcg      120

accccauccc ggaggagcug uacgagaugc ugagcgacca cuccauccgc agcuucgacg      180

accuccagcg gcugcugcac ggggaccccg gcgaggagga cggggcggag cucgaccuga      240

acaugacccg cucccacagc ggcggggagc uggagucccu cgcccggggc cgccggagcc      300

ugggcucccu gaccaucgcc gagcccgcca ugaucgccga gugcaagacg cgcaccgagg      360

ucuucgagau cagccggcgc cucaucgacc ggaccaacgc gaacuuccug guguggcccc      420

cgugcgugga gguccagcgc ugcuccgggu gcugcaacaa ccggaacgug cagugccgcc      480

ccacccaggu gcagcugcgg cccguccagg ugcgcaagau cgagaucgug cggaagaagc      540

ccaucuucaa gaaggccacg gucacccucg aggaccaccu ggccugcaag ugcgagaccg      600

uggccgcggc ccgcccggug acccggagcc ccggcggguc ccaggagcag cgcgccaaga      660

cgccccagac ccgggucacc auccgcaccg ugcgcgugcg gcggcccccg aagggcaagc      720

accgcaaguu caagcacacg cacgacaaga ccgcccugaa ggagacccuc ggggccugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  2771
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt1)

<400>  2771
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

uguucggccu ccugcugcuc accuccgccc uggccgggca gcgccagggc acccaggcgg      120

agagcaaccu guccagcaag uuccaguucu ccagcaacaa ggagcagaac ggggugcagg      180

acccccagca cgagcggauc aucacggucu ccaccaacgg cagcauccac uccccgcgcu      240

ucccccacac cuacccccgg aacaccgugc ucguguggcg ccuggucgcc guggaggaga      300

acguguggau ccagcugacg uucgacgagc gguucgggcu cgaggacccc gaggacgaca      360

ucugcaagua cgacuucguc gagguggagg agccgagcga cggcaccauc cugggccgcu      420

ggugcggguc cggcaccgug cccgggaagc agaucagcaa gggcaaccag auccggaucc      480

gcuucgucuc cgacgaguac uuccccagcg agcccggguu cugcauccac uacaacaucg      540

ugaugccgca guucaccgag gccguguccc ccagcguccu gccgcccucc gcccuccccc      600

uggaccugcu caacaacgcc aucacggcgu ucagcacccu ggaggaccug auccgguacc      660

ucgagcccga gcgcuggcag cuggaccugg aggaccucua ccggcccacc uggcagcugc      720

ugggcaaggc cuucguguuc ggccgcaagu cccggguggu cgaccucaac cugcugaccg      780

aggaggugcg ccucuacagc ugcacgcccc ggaacuucag cguguccauc cgcgaggagc      840

ugaagcggac cgacaccauc uucuggccgg ggugccugcu cgucaagcgc ugcggcggga      900

acugcgccug cugccugcac aacugcaacg agugccagug cgugcccagc aaggugacca      960

agaaguacca cgagguccug cagcuccggc ccaagacggg cgugcgcggc cugcacaagu     1020

cccugaccga cguggcccuc gagcaccacg aggagugcga cugcgucugc cgggggagca     1080

ccggcgggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  2772
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt1)

<400>  2772
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

gccugaucuu cguguacacc cucaucugcg ccaacuucug cagcugccgg gacaccuccg      120

ccacgcccca gagcgcgucc aucaaggccc ugcgcaacgc caaccugcgg cgcgacgacc      180

ucuaccggcg cgacgagacc auccagguca agggcaacgg guacgugcag agcccccggu      240

uccccaacuc cuacccccgc aaccugcugc ucaccuggcg gcugcacagc caggagaaca      300

cccgcaucca gcugguguuc gacaaccagu ucggccucga ggaggccgag aacgacaucu      360

gccgguacga cuucgucgag guggaggaca ucuccgagac cagcaccauc auccgcgggc      420

gguggugcgg ccacaaggag gugcccccgc gcaucaaguc ccggaccaac cagaucaaga      480

ucaccuucaa gagcgacgac uacuucgucg ccaagcccgg guucaagauc uacuacuccc      540

ugcuggagga cuuccagccc gcggccgcca gcgagacgaa cugggagucc gugaccagcu      600

ccaucagcgg cguguccuac aacagccccu ccgucaccga cccgacccuc aucgccgacg      660

cgcuggacaa gaagaucgcc gaguucgaca cgguggagga ccugcucaag uacuucaacc      720

ccgagagcug gcaggaggac cuggagaaca uguaccugga caccccgcgc uaccggggcc      780

gcagcuacca cgaccggaag uccaaggugg accucgaccg ccugaacgac gacgccaagc      840

gguacagcug cacgccccgc aacuacuccg ucaacauccg cgaggagcug aagcucgcca      900

acgugguguu cuucccccgg ugccugcugg uccagcgcug cgggggcaac ugcgggugcg      960

gcaccgugaa cuggcggagc ugcacgugca acuccgggaa gaccgugaag aaguaccacg     1020

agguccucca guucgagccc ggccacauca agcgccgggg ccgcgccaag accauggcgc     1080

ugguggacau ccagcuggac caccacgagc ggugcgacug caucugcagc ucccgcccgc     1140

cccggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  2773
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt1)

<400>  2773
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguga       60

cccacagcaa guuccccgcc gccggcaugu cccgcccgcu ggacaccagc cuccggcuga      120

agacguucuc cagcaagucc gaguaccagc uggucgugaa cgcggugcgc aagcuccagg      180

agagcggguu cuacuggucc gccgucaccg gcggggaggc caaccugcug cucagcgccg      240

agcccgccgg caccuuccug auccgggacu ccagcgacca gcgccacuuc uucacccugu      300

ccgugaagac gcagagcggg accaagaacc uccggaucca gugcgagggc ggcuccuuca      360

gccugcaguc cgacccccgc agcacccagc ccgugccgcg guucgacugc guccugaagc      420

ucgugcacca cuacaugccc ccgcccgggg cgcccuccuu ccccagcccg cccaccgagc      480

ccuccagcga ggugcccgag cagcccagcg cccagccccu gccgggcucc ccgccccgcc      540

gggccuacua caucuacagc gggggcgaga agaucccccu gguccucucc cgcccccuga      600

gcuccaacgu ggccacgcug cagcaccucu gccggaagac cgugaacggg caccuggaca      660

gcuacgagaa ggucacccag cugcccggcc ccauccgcga guuccucgac caguacgacg      720

cgccccugug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  2774
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt1)

<400>  2774
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugc       60

ccagcgccgg ccagcuggcc cucuucgcgc uggggaucgu ccuggccgcc ugccaggccc      120

ucgagaacuc caccagcccg cuguccgccg acccgcccgu ggcggccgcc guggucagcc      180

acuucaacga cugccccgac ucccacaccc aguucugcuu ccacggcacg ugccgcuucc      240

uggugcagga ggacaagccc gccugcgugu gccacagcgg guacgucggc gcgcggugcg      300

agcacgccga ccuccuggcc gugguggccg ccucccagaa gaagcaggcg aucaccgccc      360

uggucguggu gagcaucguc gcccucgccg ugcugaucau cacgugcgug cugauccacu      420

gcugccaggu ccgcaagcac ugcgaguggu gccgggcccu caucugccgc cacgagaagc      480

ccuccgcgcu gcugaagggg cggaccgccu gcugccacag cgagaccgug gugugaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  2775
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt1)

<400>  2775
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

cgagcggccu gcgccuccug ccccugcucc ugccccugcu cuggcugcug gugcucaccc      120

ccgggcggcc ggccgccggc cuguccacgu gcaagaccau cgacauggag cuggucaagc      180

gcaagcggau cgaggcgauc cgcgggcaga uccucagcaa gcugcggcug gccuccccgc      240

ccagccaggg cgaggugccg cccgggcccc uccccgaggc cgugcuggcc cuguacaacu      300

ccacccgcga ccgggucgcc ggcgagagcg cggagcccga gcccgagccc gaggccgacu      360

acuacgccaa ggaggugacc cgcgugcuca uggucgagac ccacaacgag aucuacgaca      420

aguucaagca guccacgcac agcaucuaca uguucuucaa caccuccgag cugcgggagg      480

ccgugcccga gcccgugcug cucagccgcg cggagcugcg gcugcuccgc cugaagcuga      540

aggucgagca gcacguggag cucuaccaga aguacuccaa caacagcugg cgguaccugu      600

ccaaccgccu gcucgccccg agcgacuccc ccgaguggcu gagcuucgac gugaccggcg      660

ucgugcggca guggcugucc cgcgggggcg agaucgaggg guuccggcuc agcgcccacu      720

gcuccugcga cagccgcgac aacacccucc agguggacau caacggcuuc acgaccgggc      780

ggcgcggcga ccuggccacc auccacggca ugaaccggcc cuuccugcug cugauggcca      840

cgccccucga gcgcgcgcag caccuccaga gcucccgcca ccggcgcgcc cuggacacca      900

acuacugcuu cagcuccacc gagaagaacu gcugcguccg gcagcuguac aucgacuucc      960

gcaaggaccu gggguggaag uggauccacg agccgaaggg cuaccacgcc aacuucugcc     1020

uggggcccug ccccuacauc uggagccucg acacccagua cuccaaggug cuggcccugu     1080

acaaccagca caaccccggc gccagcgcgg ccccgugcug cgugccccag gcccucgagc     1140

cccugcccau cgucuacuac gugggccgga agccgaaggu ggagcagcug uccaacauga     1200

ucguccgcag cugcaagugc uccugaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  2776
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt1)

<400>  2776
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugcgugcu gagcgccuuc cucauccugc accuggucac cguggcccuc ucccugagca      120

cgugcuccac ccuggacaug gaccaguuca ugcgcaagcg gaucgaggcg auccgcggcc      180

agauccucag caagcugaag cugaccagcc cgcccgagga cuaccccgag cccgaggagg      240

ugcccccgga ggucaucucc aucuacaacu ccacccggga ccuccugcag gagaaggcca      300

gccgccgggc cgccgccugc gagcgcgagc gguccgacga ggaguacuac gcgaaggagg      360

uguacaagau cgacaugccg cccuucuucc ccagcgagaa cgccaucccg cccaccuucu      420

accgccccua cuuccggauc gugcgcuucg acgucuccgc cauggagaag aacgccagca      480

accuggugaa ggcggaguuc cggguguucc gccuccagaa ccccaaggcc cggguccccg      540

agcagcgcau cgagcuguac cagauccuga aguccaagga ccucacgagc cccacccagc      600

gguacaucga cuccaaggug gugaagaccc gcgccgaggg ggaguggcug agcuucgacg      660

ucaccgacgc cgugcacgag uggcugcacc acaaggaccg gaaccucggc uucaagaucu      720

cccugcacug ccccugcugc acguucgugc ccagcaacaa cuacaucauc ccgaacaagu      780

ccgaggagcu ggaggcccgc uucgcgggga ucgacggcac cagcaccuac accagcgggg      840

accagaagac gaucaagucc acccggaaga agaacagcgg caagacgccc caccuccugc      900

ugaugcuccu gcccuccuac cgccuggaga gccagcagac caaccggcgc aagaagcgcg      960

cccucgacgc cgccuacugc uuccggaacg uccaggacaa cugcugccug cgcccccugu     1020

acaucgacuu caagcgggac cucggcugga aguggaucca cgagccgaag ggguacaacg     1080

ccaacuucug cgcgggcgcc ugccccuacc ugugguccag cgacacccag cacucccgcg     1140

ugcugagccu cuacaacacc aucaaccccg aggccuccgc cagccccugc ugcguguccc     1200

aggaccugga gccgcugacc auccucuacu acaucgggaa gacccccaag aucgagcagc     1260

ugagcaacau gaucgucaag uccugcaagu gcagcugagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  2777
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt1)

<400>  2777
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

ugcaccucca gcgcgcccuc guggugcugg cccugcucaa cuucgcgacc gugagccugu      120

cccugagcac gugcaccacc cucgacuucg gccacaucaa gaagaagcgg guggaggcca      180

uccgcgggca gauccugucc aagcugcggc ucaccagccc gcccgagccc accgucauga      240

cgcacgugcc cuaccaggug cuggcccugu acaacuccac ccgcgagcuc cuggaggaga      300

ugcacggcga gcgggaggag gggugcaccc aggagaacac cgagagcgag uacuacgcca      360

aggagaucca caaguucgac augauccagg gccuggccga gcacaacgag cucgcggucu      420

gccccaaggg gaucacgucc aagguguucc gcuucaacgu gagcuccguc gagaagaacc      480

ggaccaaccu guuccgcgcc gaguuccggg ugcugcgcgu gccgaacccc agcuccaagc      540

ggaacgagca gcgcaucgag cuguuccaga uccugcggcc cgacgagcac aucgccaagc      600

agcgcuacau cggcggcaag aaccugccca cccgggggac cgccgagugg cucagcuucg      660

acgucacgga caccgugcgc gaguggcugc ugcggcgcga guccaaccuc ggccuggaga      720

ucagcaucca cugcccgugc cacaccuucc agcccaacgg ggacauccug gagaacaucc      780

acgaggugau ggagaucaag uucaagggcg ucgacaacga ggacgaccac gggcggggcg      840

accucggccg ccugaagaag cagaaggacc accacaaccc ccaccugauc cucaugauga      900

ucccgcccca ccggcuggac aaccccgggc agggcgggca gcgcaagaag cgcgcgcugg      960

acaccaacua cugcuuccgg aaccucgagg agaacugcug cgugcgcccc cuguacaucg     1020

acuuccggca ggaccugggc uggaaguggg ugcacgagcc caagggcuac uacgccaacu     1080

ucugcuccgg gccgugcccc uaccuccgca gcgccgacac gacccacucc accguccugg     1140

gccuguacaa cacccucaac cccgaggcca gcgccucccc cugcugcgug ccgcaggacc     1200

uggagccccu gacgauccuc uacuacgugg ggcggacccc caaggucgag cagcugagca     1260

acaugguggu caagagcugc aagugcuccu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2778
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt1)

<400>  2778
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ccguggccgu cugggcggcc cuggccgugg gccucgagcu gugggccgcc gcgcacgccc      120

ugccggccca gguggccuuc acccccuacg cgcccgagcc cgggagcacg ugccgccucc      180

gggaguacua cgaccagacc gcccagaugu gcugcuccaa gugcagcccg ggccagcacg      240

ccaaggucuu cugcaccaag accuccgaca ccgugugcga cagcugcgag gacuccacgu      300

acacccagcu guggaacugg gugcccgagu gccugagcug cgggucccgc ugcagcuccg      360

accaggucga gacccaggcc ugcacccggg agcagaaccg caucugcacg ugccggcccg      420

gcugguacug cgcccucagc aagcaggagg ggugccgccu gugcgcgccc cugcggaagu      480

gccgcccggg cuucggcgug gcccggcccg ggaccgagac cuccgacgug gucugcaagc      540

ccugcgcccc cggcaccuuc agcaacacga ccuccagcac cgacaucugc cgcccgcacc      600

agaucugcaa cgugguggcc auccccggga acgccuccau ggacgcgguc ugcaccagca      660

cgucccccac ccggagcaug gcccccggcg ccgugcaccu cccgcagccc guguccaccc      720

gcagccagca cacccagccc acgcccgagc cgagcaccgc ccccuccacc agcuuccugc      780

ugcccauggg gcccuccccg cccgccgagg gcagcaccgg cgacuucgcg cuccccgucg      840

ggcugaucgu gggcgugacg gcccuggggc uccugaucau cggcgucgug aacugcguga      900

ucaugaccca ggucaagaag aagccccugu gccuccagcg ggaggccaag gugccgcacc      960

uccccgccga caaggcccgc ggcacccagg ggcccgagca gcagcaccuc cugaucaccg     1020

cgccguccag cuccagcucc agccuggagu ccagcgccuc cgcccuggac cggcgcgccc     1080

ccacgcggaa ccagccccag gcgcccggcg uggaggccag cggggccggc gaggcccgcg     1140

ccuccaccgg gagcuccgac agcuccccgg gcggccacgg gacccagguc aacgugaccu     1200

gcaucgucaa cgugugcagc agcuccgacc acagcuccca gugcagcucc caggcgagcu     1260

ccacgauggg cgacaccgac agcuccccca gcgagucccc caaggacgag cagguccccu     1320

ucagcaagga ggagugcgcc uuccgguccc agcuggagac cccggagacc cugcugggga     1380

gcacggagga gaagccccuc ccccugggcg ugcccgacgc cgggaugaag ccguccugag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  2779
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt1)

<400>  2779
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

ugaugcgccu guucccgugc uuccuccagc ugcuggccgg ccucgcccug cccgcggucc      120

cgccccagca gugggcccug agcgccggga acggcuccag cgagguggag gugguccccu      180

uccaggaggu gugggggcgg uccuacugcc gcgcccucga gcggcuggug gacgucguga      240

gcgaguaccc cuccgaggug gagcacaugu ucagccccuc cugcgucagc cugcuccgcu      300

gcaccggcug cugcggggac gagaaccugc acugcgugcc cguggagacc gccaacguca      360

cgaugcagcu gcucaagauc cgguccggcg accgcccgag cuacguggag cugaccuucu      420

cccagcacgu gcggugcgag ugccgccccc ugcgggagaa gaugaagccc gagcgccggc      480

gccccaaggg ccgggggaag cgccggcgcg agaagcagcg gccgaccgac ugccaccucu      540

gcggcgacgc ggucccccgc cggugaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  2780
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt1)

<400>  2780
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

accgccagac cgacacggcc cccagcccgu ccuaccaccu ccugcccggc cggcgccgga      120

ccguggacgc cgcggccagc cgcgggcagg gccccgagcc cgcccccggg ggcggggucg      180

agggcguggg cgcccgcggg guggcccuga agcuguucgu ccagcuccug ggcugcuccc      240

gguucggggg cgcgguggug cgggccgggg aggccgagcc cagcggcgcc gcgcgcuccg      300

ccagcuccgg ccgggaggag ccccagcccg aggaggggga ggaggaggag gagaaggagg      360

aggagcgcgg cccgcagugg cggcuggggg cccgcaagcc cggcagcugg accggcgagg      420

ccgccgucug cgcggacucc gcccccgccg cccgggcccc gcaggcgcuc gcccgcgcca      480

gcgggcgggg cgggcgcgug gcccggcgcg gcgccgagga guccgggccg ccccacagcc      540

ccucccggcg cggcagcgcg ucccgggccg gccccgggcg cgccagcgag accaugaacu      600

uccugcuguc cugggugcac uggagccucg cccugcugcu cuaccugcac cacgccaagu      660

ggucccaggc ggccccgaug gccgagggcg ggggccagaa ccaccacgag gucgugaagu      720

ucauggacgu guaccagcgc agcuacugcc accccaucga gacgcugguc gacaucuucc      780

aggaguaccc cgacgagauc gaguacaucu ucaagcccag cugcgugccg cucaugcggu      840

gcgggggcug cugcaacgac gagggccugg agugcgugcc caccgaggag uccaacauca      900

ccaugcagau caugcgcauc aagccccacc aggggcagca caucggcgag augagcuucc      960

ugcagcacaa caagugcgag ugccggccca agaaggaccg cgcccggcag gagaagaagu     1020

ccguccgcgg gaagggcaag gggcagaagc ggaagcgcaa gaagucccgg uacaagagcu     1080

ggagcgugua cgugggcgcg cgcugcugcc ucaugccgug gucccugccc ggcccccacc     1140

ccugcgggcc gugcagcgag cggcgcaagc accuguucgu ccaggacccc cagaccugca     1200

agugcuccug caagaacacg gacagccggu gcaaggcccg ccagcucgag cugaacgagc     1260

ggaccugccg cugcgacaag ccccggcgcu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2781
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt1)

<400>  2781
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugcucag cugggugcac uggucccugg cccugcuccu guaccugcac cacgccaagu      120

ggagccaggc ggcccccaug gccgagggcg ggggccagaa ccaccacgag gucgugaagu      180

ucauggacgu guaccagcgc uccuacugcc acccgaucga gacccucguc gacaucuucc      240

aggaguaccc cgacgagauc gaguacaucu ucaagcccag cugcgugccc cugaugcggu      300

gcgggggcug cugcaacgac gaggggcugg agugcgugcc gaccgaggag uccaacauca      360

cgaugcagau caugcgcauc aagccccacc agggccagca caucggcgag augagcuucc      420

uccagcacaa caagugcgag ugccggccca agaaggaccg cgcccggcag gagaagaagu      480

ccguccgcgg gaagggcaag gggcagaagc ggaagcgcaa gaagucccgg uacaagagcu      540

ggagcgugua cgugggcgcc cgcugcugcc ugaugcccug gucccugccg gggccccacc      600

ccugcggccc cugcagcgag cggcgcaagc accucuucgu ccaggacccg cagaccugca      660

agugcuccug caagaacacc gacagccggu gcaaggcgcg ccagcuggag cugaacgagc      720

ggaccugccg cugcgacaag ccccggcgcu gaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  2782
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt1)

<400>  2782
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

cccugcuccg ccggcugcug cucgccgccc ugcugcagcu cgcgccggcc caggcccccg      120

ugucccagcc cgacgccccc ggccaccagc gcaaggucgu gagcuggauc gacguguaca      180

cccgggcgac cugccagccg cgcgaggucg uggugccccu gacggucgag cugaugggga      240

ccguggccaa gcagcucgug cccuccugcg ucaccgugca gcggugcggc gggugcugcc      300

ccgacgacgg ccuggagugc gugccgaccg ggcagcacca gguccgcaug cagauccuga      360

ugauccggua ccccagcucc cagcucggcg agaugagccu ggaggagcac ucccagugcg      420

agugccgccc caagaagaag gacagcgccg ugaagcccga ccgggccgcc acgccgcacc      480

accgccccca gccccggucc gugcccggcu gggacagcgc gccgggggcc cccucccccg      540

ccgacaucac ccaccccacc ccggcccccg gccccagcgc ccacgcggcc cccuccacca      600

cgagcgcccu gaccccgggg cccgccgccg cggccgccga cgccgccgcg uccagcgucg      660

ccaagggcgg ggccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  2783
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt1)

<400>  2783
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

uccugggcuu cuucagcgug gccugcuccc ugcuggccgc ggcccuccug cccgggccgc      120

gcgaggcccc cgccgccgcg gccgccuucg agagcggccu ggaccucucc gacgccgagc      180

ccgacgcggg ggaggccacc gccuacgcca gcaaggaccu ggaggagcag cugcgguccg      240

ucagcuccgu ggacgagcuc augaccgugc uguaccccga guacuggaag auguacaagu      300

gccagcugcg caagggcggg uggcagcaca accgggagca ggccaaccuc aacagccgca      360

cggaggagac caucaaguuc gcggccgccc acuacaacac cgagauccug aaguccaucg      420

acaacgagug gcggaagacc cagugcaugc cgcgcgaggu cugcaucgac gugggcaagg      480

aguucggcgu ggccacgaac accuucuuca agccgcccug cgucagcgug uaccggugcg      540

ggggcugcug caacuccgag gggcugcagu gcaugaacac cagcaccucc uaccucagca      600

agacgcuguu cgagaucacc gugccccugu cccagggccc caagcccguc accaucagcu      660

ucgccaacca caccuccugc cgcugcauga gcaagcucga cguguaccgc caggugcacu      720

ccaucauccg gcggagccug cccgcgacgc ugccccagug ccaggccgcc aacaagaccu      780

gcccgaccaa cuacaugugg aacaaccaca ucugccgcug ccucgcccag gaggacuuca      840

uguucagcuc cgacgccggg gacgacagca ccgacggcuu ccacgacauc ugcggcccca      900

acaaggagcu ggacgaggag acgugccagu gcgucugccg ggcggggcug cgccccgccu      960

ccugcggccc ccacaaggag cucgaccgga acagcugcca gugcgugugc aagaacaagc     1020

uguucccguc ccagugcggg gccaaccgcg aguucgacga gaacacgugc cagugcgugu     1080

gcaagcggac cugcccccgc aaccagcccc ugaaccccgg caagugcgcc ugcgagugca     1140

ccgagagccc gcagaagugc cuccugaagg gcaagaaguu ccaccaccag accugcuccu     1200

gcuaccggcg ccccugcacc aaccggcaga aggccugcga gcccggguuc agcuacuccg     1260

aggaggucug ccgcugcgug cccagcuacu ggaagcgccc gcagaugucc ugaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  2784
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt1)

<400>  2784
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguacc       60

gcgagugggu ggucgugaac guguucauga ugcuguacgu ccagcucgug cagggcagcu      120

ccaacgagca cgggcccgug aagcggagcu cccagagcac ccuggagcgc uccgagcagc      180

agauccgggc cgccagcucc cuggaggagc uccugcgcau cacccacagc gaggacugga      240

agcuguggcg gugccgccuc cggcugaagu ccuucacgag cauggacucc cgcagcgcgu      300

cccaccggag cacccgcuuc gccgccaccu ucuacgacau cgagacccug aaggucaucg      360

acgaggagug gcagcggacg cagugcuccc cgcgcgagac cugcguggag guggccagcg      420

agcucggcaa guccaccaac accuucuuca agccgcccug cgucaacgug uuccggugcg      480

ggggcugcug caacgaggag agccugaucu gcaugaacac guccaccagc uacaucagca      540

agcagcuguu cgagaucucc gugccccuca ccagcguccc cgagcuggug cccgugaagg      600

ucgccaacca caccgggugc aagugccugc ccacggcgcc ccgccacccg uacuccauca      660

uccggcgcag cauccagauc cccgaggagg accggugcuc ccacagcaag aagcucugcc      720

ccaucgacau gcugugggac uccaacaagu gcaagugcgu gcugcaggag gagaaccccc      780

ucgccggcac cgaggaccac agccaccucc aggagccggc ccugugcggc ccccacauga      840

uguucgacga ggaccgcugc gagugcgugu gcaagacccc cugccccaag gaccugaucc      900

agcacccgaa gaacugcucc ugcuucgagu gcaaggagag ccuggagacc ugcugccaga      960

agcacaagcu guuccacccc gacacgugcu ccugcgagga ccggugcccc uuccacaccc     1020

gccccugcgc cagcgggaag accgcgugcg ccaagcacug ccgguucccg aaggagaagc     1080

gcgccgccca gggcccccac ucccgcaaga accccugagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  2785
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt2)

<400>  2785
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

ccgacgagac cggcuucgag cacuccggcc ucugggucuc cguccucgcc ggccuccucc      120

ucggcgccug ccaggcccac cccauccccg acuccucccc ccuccuccag uucggcggcc      180

agguccgcca gcgcuaccuc uacaccgacg acgcccagca gaccgaggcc caccucgaga      240

uccgcgagga cggcaccguc ggcggcgccg ccgaccaguc ccccgagucc cuccuccagc      300

ucaaggcccu caagcccggc gucauccaga uccucggcgu caagaccucc cgcuuccucu      360

gccagcgccc cgacggcgcc cucuacggcu cccuccacuu cgaccccgag gccugcuccu      420

uccgcgagcu ccuccucgag gacggcuaca acgucuacca guccgaggcc cacggccucc      480

cccuccaccu ccccggcaac aagucccccc accgcgaccc cgccccccgc ggccccgccc      540

gcuuccuccc ccuccccggc cucccccccg cccuccccga gccccccggc auccucgccc      600

cccagccccc cgacgucggc uccuccgacc cccucuccau ggucggcccc ucccagggcc      660

gcucccccuc cuacgccucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  2786
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt2)

<400>  2786
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

ccuucccccc ccuccuccuc cuccucuucu ggggcgucgu cucccacucc uuccccgcca      120

cccucgagac ccaggagcag gacgucgacc ucguccagaa guaccucgag aaguacuaca      180

accucaagaa cgacggccgc caggucgaga agcgccgcaa cuccggcccc gucgucgaga      240

agcucaagca gaugcaggag uucuucggcc ucaaggucac cggcaagccc gacgccgaga      300

cccucaaggu caugaagcag ccccgcugcg gcguccccga cgucgcccag uucguccuca      360

ccgagggcaa cccccgcugg gagcagaccc accucaccua ccgcaucgag aacuacaccc      420

ccgaccuccc ccgcgccgac gucgaccacg ccaucgagaa ggccuuccag cucuggucca      480

acgucacccc ccucaccuuc accaaggucu ccgagggcca ggccgacauc augaucuccu      540

ucguccgcgg cgaccaccgc gacaacuccc ccuucgacgg ccccggcggc aaccucgccc      600

acgccuucca gcccggcccc ggcaucggcg gcgacgccca cuucgacgag gacgagcgcu      660

ggaccaacaa cuuccgcgag uacaaccucc accgcgucgc cgcccacgag cucggccacu      720

cccucggccu cucccacucc accgacaucg gcgcccucau guaccccucc uacaccuucu      780

ccggcgacgu ccagcucgcc caggacgaca ucgacggcau ccaggccauc uacggccgcu      840

cccagaaccc cguccagccc aucggccccc agacccccaa ggccugcgac uccaagcuca      900

ccuucgacgc caucaccacc auccgcggcg aggucauguu cuucaaggac cgcuucuaca      960

ugcgcaccaa ccccuucuac cccgaggucg agcucaacuu caucuccguc uucuggcccc     1020

agcuccccaa cggccucgag gccgccuacg aguucgccga ccgcgacgag guccgcuucu     1080

ucaagggcaa caaguacugg gccguccagg gccagaacgu ccuccacggc uaccccaagg     1140

acaucuacuc cuccuucggc uucccccgca ccgucaagca caucgacgcc gcccucuccg     1200

aggagaacac cggcaagacc uacuucuucg ucgccaacaa guacuggcgc uacgacgagu     1260

acaagcgcuc cauggacccc ggcuacccca agaugaucgc ccacgacuuc cccggcaucg     1320

gccacaaggu cgacgccguc uucaugaagg acggcuucuu cuacuucuuc cacggcaccc     1380

gccaguacaa guucgacccc aagaccaagc gcauccucac ccuccagaag gccaacuccu     1440

gguucaacug ccgcaagaac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  2787
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt2)

<400>  2787
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

ccuucccccc ccuccuccuc cuccucuucu ggggcgucgu cucccacucc uucguccuca      120

ccgagggcaa cccccgcugg gagcagaccc accucaccua ccgcaucgag aacuacaccc      180

ccgaccuccc ccgcgccgac gucgaccacg ccaucgagaa ggccuuccag cucuggucca      240

acgucacccc ccucaccuuc accaaggucu ccgagggcca ggccgacauc augaucuccu      300

ucguccgcgg cgaccaccgc gacaacuccc ccuucgacgg ccccggcggc aaccucgccc      360

acgccuucca gcccggcccc ggcaucggcg gcgacgccca cuucgacgag gacgagcgcu      420

ggaccaacaa cuuccgcgag uacaaccucc accgcgucgc cgcccacgag cucggccacu      480

cccucggccu cucccacucc accgacaucg gcgcccucau guaccccucc uacaccuucu      540

ccggcgacgu ccagcucgcc caggacgaca ucgacggcau ccaggccauc uacggccgcu      600

cccagaaccc cguccagccc aucggccccc agacccccaa ggccugcgac uccaagcuca      660

ccuucgacgc caucaccacc auccgcggcg aggucauguu cuucaaggac cgcuucuaca      720

ugcgcaccaa ccccuucuac cccgaggucg agcucaacuu caucuccguc uucuggcccc      780

agcuccccaa cggccucgag gccgccuacg aguucgccga ccgcgacgag guccgcuucu      840

ucaagggcaa caaguacugg gccguccagg gccagaacgu ccuccacggc uaccccaagg      900

acaucuacuc cuccuucggc uucccccgca ccgucaagca caucgacgcc gcccucuccg      960

aggagaacac cggcaagacc uacuucuucg ucgccaacaa guacuggcgc uacgacgagu     1020

acaagcgcuc cauggacccc ggcuacccca agaugaucgc ccacgacuuc cccggcaucg     1080

gccacaaggu cgacgccguc uucaugaagg acggcuucuu cuacuucuuc cacggcaccc     1140

gccaguacaa guucgacccc aagaccaagc gcauccucac ccuccagaag gccaacuccu     1200

gguucaacug ccgcaagaac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  2788
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt2)

<400>  2788
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

agaacauccu caagauccuc auggacuccu acuccaagga guccaagauc cagaccgucc      120

gccgcgucac cuccgucucc cuccucgccg ucuaccucac caugaacacc uccucccucg      180

uccucgccaa gcccaucgag aacaccaacg acaccuccau caagaacguc gagaagcucc      240

gcaacgcccc caacgaggag aacuccaaga aggucgagga cuccaagaac gacaaggucg      300

agcacgucaa gaacaucgag gaggccaagg ucgagcaggu cgcccccgag gucaagucca      360

aguccacccu ccgcuccgcc uccaucgcca acaccaacuc cgagaaguac gacuucgagu      420

accucaacgg ccucuccuac accgagcuca ccaaccucau caagaacauc aaguggaacc      480

agaucaacgg ccucuucaac uacuccaccg gcucccagaa guucuucggc gacaagaacc      540

gcguccaggc caucaucaac gcccuccagg aguccggccg caccuacacc gccaacgaca      600

ugaagggcau cgagaccuuc accgaggucc uccgcgccgg cuucuaccuc ggcuacuaca      660

acgacggccu cuccuaccuc aacgaccgca acuuccagga caagugcauc cccgccauga      720

ucgccaucca gaagaacccc aacuucaagc ucggcaccgc cguccaggac gaggucauca      780

ccucccucgg caagcucauc ggcaacgccu ccgccaacgc cgaggucguc aacaacugcg      840

uccccguccu caagcaguuc cgcgagaacc ucaaccagua cgcccccgac uacgucaagg      900

gcaccgccgu caacgagcuc aucaagggca ucgaguucga cuucuccggc gccgccuacg      960

agaaggacgu caagaccaug cccugguacg gcaagaucga ccccuucauc aacgagcuca     1020

aggcccucgg ccucuacggc aacaucaccu ccgccaccga gugggccucc gacgucggca     1080

ucuacuaccu cuccaaguuc ggccucuacu ccaccaaccg caacgacauc guccaguccc     1140

ucgagaaggc cgucgacaug uacaaguacg gcaagaucgc cuucgucgcc auggagcgca     1200

ucaccuggga cuacgacggc aucggcucca acggcaagaa ggucgaccac gacaaguucc     1260

ucgacgacgc cgagaagcac uaccucccca agaccuacac cuucgacaac ggcaccuuca     1320

ucauccgcgc cggcgacaag gucuccgagg agaagaucaa gcgccucuac ugggccuccc     1380

gcgaggucaa gucccaguuc caccgcgucg ucggcaacga caaggcccuc gaggucggca     1440

acgccgacga cguccucacc augaagaucu ucaacucccc cgaggaguac aaguucaaca     1500

ccaacaucaa cggcgucucc accgacaacg gcggccucua caucgagccc cgcggcaccu     1560

ucuacaccua cgagcgcacc ccccagcagu ccaucuucuc ccucgaggag cucuuccgcc     1620

acgaguacac ccacuaccuc caggcccgcu accucgucga cggccucugg ggccagggcc     1680

ccuucuacga gaagaaccgc cucaccuggu ucgacgaggg caccgccgag uucuucgccg     1740

gcuccacccg caccuccggc guccuccccc gcaaguccau ccucggcuac cucgccaagg     1800

acaaggucga ccaccgcuac ucccucaaga agacccucaa cuccggcuac gacgacuccg     1860

acuggauguu cuacaacuac ggcuucgccg ucgcccacua ccucuacgag aaggacaugc     1920

ccaccuucau caagaugaac aaggccaucc ucaacaccga cgucaagucc uacgacgaga     1980

ucaucaagaa gcucuccgac gacgccaaca agaacaccga guaccagaac cacauccagg     2040

agcucgccga caaguaccag ggcgccggca ucccccucgu cuccgacgac uaccucaagg     2100

accacggcua caagaaggcc uccgaggucu acuccgagau cuccaaggcc gccucccuca     2160

ccaacaccuc cgucaccgcc gagaaguccc aguacuucaa caccuucacc cuccgcggca     2220

ccuacaccgg cgagaccucc aagggcgagu ucaaggacug ggacgagaug uccaagaagc     2280

ucgacggcac ccucgagucc cucgccaaga acuccugguc cggcuacaag acccucaccg     2340

ccuacuucac caacuaccgc gucaccuccg acaacaaggu ccaguacgac gucgucuucc     2400

acggcguccu caccgacaac gccgacaucu ccaacaacaa ggcccccauc gccaagguca     2460

ccggccccuc caccggcgcc gucggccgca acaucgaguu cuccggcaag gacuccaagg     2520

acgaggacgg caagaucguc uccuacgacu gggacuucgg cgacggcgcc accucccgcg     2580

gcaagaacuc cguccacgcc uacaagaagg ccggcaccua caacgucacc cucaagguca     2640

ccgacgacaa gggcgccacc gccaccgagu ccuucaccau cgagaucaag aacgaggaca     2700

ccaccacccc caucaccaag gagauggagc ccaacgacga caucaaggag gccaacggcc     2760

ccaucgucga gggcgucacc gucaagggcg accucaacgg cuccgacgac gccgacaccu     2820

ucuacuucga cgucaaggag gacggcgacg ucaccaucga gcuccccuac uccggcuccu     2880

ccaacuucac cuggcucguc uacaaggagg gcgacgacca gaaccacauc gccuccggca     2940

ucgacaagaa caacuccaag gucggcaccu ucaaguccac caagggccgc cacuacgucu     3000

ucaucuacaa gcacgacucc gccuccaaca ucuccuacuc ccucaacauc aagggccucg     3060

gcaacgagaa gcucaaggag aaggagaaca acgacuccuc cgacaaggcc accgucaucc     3120

ccaacuucaa caccaccaug cagggcuccc uccucggcga cgacucccgc gacuacuacu     3180

ccuucgaggu caaggaggag ggcgagguca acaucgagcu cgacaagaag gacgaguucg     3240

gcgucaccug gacccuccac cccgagucca acaucaacga ccgcaucacc uacggccagg     3300

ucgacggcaa caaggucucc aacaagguca agcuccgccc cggcaaguac uaccuccucg     3360

ucuacaagua cuccggcucc ggcaacuacg agcuccgcgu caacaaguga ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  2789
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt2)

<400>  2789
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggucaccuu caucucccuc cucuuccucu ucuccuccgc cuacuccauc gccaacacca      120

acuccgagaa guacgacuuc gaguaccuca acggccucuc cuacaccgag cucaccaacc      180

ucaucaagaa caucaagugg aaccagauca acggccucuu caacuacucc accggcuccc      240

agaaguucuu cggcgacaag aaccgcgucc aggccaucau caacgcccuc caggaguccg      300

gccgcaccua caccgccaac gacaugaagg gcaucgagac cuucaccgag guccuccgcg      360

ccggcuucua ccucggcuac uacaacgacg gccucuccua ccucaacgac cgcaacuucc      420

aggacaagug cauccccgcc augaucgcca uccagaagaa ccccaacuuc aagcucggca      480

ccgccgucca ggacgagguc aucaccuccc ucggcaagcu caucggcaac gccuccgcca      540

acgccgaggu cgucaacaac ugcguccccg uccucaagca guuccgcgag aaccucaacc      600

aguacgcccc cgacuacguc aagggcaccg ccgucaacga gcucaucaag ggcaucgagu      660

ucgacuucuc cggcgccgcc uacgagaagg acgucaagac caugcccugg uacggcaaga      720

ucgaccccuu caucaacgag cucaaggccc ucggccucua cggcaacauc accuccgcca      780

ccgagugggc cuccgacguc ggcaucuacu accucuccaa guucggccuc uacuccacca      840

accgcaacga caucguccag ucccucgaga aggccgucga cauguacaag uacggcaaga      900

ucgccuucgu cgccauggag cgcaucaccu gggacuacga cggcaucggc uccaacggca      960

agaaggucga ccacgacaag uuccucgacg acgccgagaa gcacuaccuc cccaagaccu     1020

acaccuucga caacggcacc uucaucaucc gcgccggcga caaggucucc gaggagaaga     1080

ucaagcgccu cuacugggcc ucccgcgagg ucaaguccca guuccaccgc gucgucggca     1140

acgacaaggc ccucgagguc ggcaacgccg acgacguccu caccaugaag aucuucaacu     1200

cccccgagga guacaaguuc aacaccaaca ucaacggcgu cuccaccgac aacggcggcc     1260

ucuacaucga gccccgcggc accuucuaca ccuacgagcg caccccccag caguccaucu     1320

ucucccucga ggagcucuuc cgccacgagu acacccacua ccuccaggcc cgcuaccucg     1380

ucgacggccu cuggggccag ggccccuucu acgagaagaa ccgccucacc ugguucgacg     1440

agggcaccgc cgaguucuuc gccggcucca cccgcaccuc cggcguccuc ccccgcaagu     1500

ccauccucgg cuaccucgcc aaggacaagg ucgaccaccg cuacucccuc aagaagaccc     1560

ucaacuccgg cuacgacgac uccgacugga uguucuacaa cuacggcuuc gccgucgccc     1620

acuaccucua cgagaaggac augcccaccu ucaucaagau gaacaaggcc auccucaaca     1680

ccgacgucaa guccuacgac gagaucauca agaagcucuc cgacgacgcc aacaagaaca     1740

ccgaguacca gaaccacauc caggagcucg ccgacaagua ccagggcgcc ggcauccccc     1800

ucgucuccga cgacuaccuc aaggaccacg gcuacaagaa ggccuccgag gucuacuccg     1860

agaucuccaa ggccgccucc cucaccaaca ccuccgucac cgccgagaag ucccaguacu     1920

ucaacaccuu cacccuccgc ggcaccuaca ccggcgagac cuccaagggc gaguucaagg     1980

acugggacga gauguccaag aagcucgacg gcacccucga gucccucgcc aagaacuccu     2040

gguccggcua caagacccuc accgccuacu ucaccaacua ccgcgucacc uccgacaaca     2100

agguccagua cgacgucguc uuccacggcg uccucaccga caacgccgac aucuccaaca     2160

acaaggcccc caucgccaag gucaccggcc ccuccaccgg cgccgucggc cgcaacaucg     2220

aguucuccgg caaggacucc aaggacgagg acggcaagau cgucuccuac gacugggacu     2280

ucggcgacgg cgccaccucc cgcggcaaga acuccgucca cgccuacaag aaggccggca     2340

ccuacaacgu cacccucaag gucaccgacg acaagggcgc caccgccacc gaguccuuca     2400

ccaucgagau caagaacgag gacaccacca cccccaucac caaggagaug gagcccaacg     2460

acgacaucaa ggaggccaac ggccccaucg ucgagggcgu caccgucaag ggcgaccuca     2520

acggcuccga cgacgccgac accuucuacu ucgacgucaa ggaggacggc gacgucacca     2580

ucgagcuccc cuacuccggc uccuccaacu ucaccuggcu cgucuacaag gagggcgacg     2640

accagaacca caucgccucc ggcaucgaca agaacaacuc caaggucggc accuucaagu     2700

ccaccaaggg ccgccacuac gucuucaucu acaagcacga cuccgccucc aacaucuccu     2760

acucccucaa caucaagggc cucggcaacg agaagcucaa ggagaaggag aacaacgacu     2820

ccuccgacaa ggccaccguc auccccaacu ucaacaccac caugcagggc ucccuccucg     2880

gcgacgacuc ccgcgacuac uacuccuucg aggucaagga ggagggcgag gucaacaucg     2940

agcucgacaa gaaggacgag uucggcguca ccuggacccu ccaccccgag uccaacauca     3000

acgaccgcau caccuacggc caggucgacg gcaacaaggu cuccaacaag gucaagcucc     3060

gccccggcaa guacuaccuc cucgucuaca aguacuccgg cuccggcaac uacgagcucc     3120

gcgucaacaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  2790
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt2)

<400>  2790
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggucaccuu caucucccuc cucuuccucu ucuccuccgc cuacuccaug aagaagaaca      120

uccucaagau ccucauggac uccuacucca aggaguccaa gauccagacc guccgccgcg      180

ucaccuccgu cucccuccuc gccgucuacc ucaccaugaa caccuccucc cucguccucg      240

ccaagcccau cgagaacacc aacgacaccu ccaucaagaa cgucgagaag cuccgcaacg      300

cccccaacga ggagaacucc aagaaggucg aggacuccaa gaacgacaag gucgagcacg      360

ucaagaacau cgaggaggcc aaggucgagc aggucgcccc cgaggucaag uccaagucca      420

cccuccgcuc cgccucccgc cgccgccgca agcgcaucgc caacaccaac uccgagaagu      480

acgacuucga guaccucaac ggccucuccu acaccgagcu caccaaccuc aucaagaaca      540

ucaaguggaa ccagaucaac ggccucuuca acuacuccac cggcucccag aaguucuucg      600

gcgacaagaa ccgcguccag gccaucauca acgcccucca ggaguccggc cgcaccuaca      660

ccgccaacga caugaagggc aucgagaccu ucaccgaggu ccuccgcgcc ggcuucuacc      720

ucggcuacua caacgacggc cucuccuacc ucaacgaccg caacuuccag gacaagugca      780

uccccgccau gaucgccauc cagaagaacc ccaacuucaa gcucggcacc gccguccagg      840

acgaggucau caccucccuc ggcaagcuca ucggcaacgc cuccgccaac gccgaggucg      900

ucaacaacug cguccccguc cucaagcagu uccgcgagaa ccucaaccag uacgcccccg      960

acuacgucaa gggcaccgcc gucaacgagc ucaucaaggg caucgaguuc gacuucuccg     1020

gcgccgccua cgagaaggac gucaagacca ugcccuggua cggcaagauc gaccccuuca     1080

ucaacgagcu caaggcccuc ggccucuacg gcaacaucac cuccgccacc gagugggccu     1140

ccgacgucgg caucuacuac cucuccaagu ucggccucua cuccaccaac cgcaacgaca     1200

ucguccaguc ccucgagaag gccgucgaca uguacaagua cggcaagauc gccuucgucg     1260

ccauggagcg caucaccugg gacuacgacg gcaucggcuc caacggcaag aaggucgacc     1320

acgacaaguu ccucgacgac gccgagaagc acuaccuccc caagaccuac accuucgaca     1380

acggcaccuu caucauccgc gccggcgaca aggucuccga ggagaagauc aagcgccucu     1440

acugggccuc ccgcgagguc aagucccagu uccaccgcgu cgucggcaac gacaaggccc     1500

ucgaggucgg caacgccgac gacguccuca ccaugaagau cuucaacucc cccgaggagu     1560

acaaguucaa caccaacauc aacggcgucu ccaccgacaa cggcggccuc uacaucgagc     1620

cccgcggcac cuucuacacc uacgagcgca ccccccagca guccaucuuc ucccucgagg     1680

agcucuuccg ccacgaguac acccacuacc uccaggcccg cuaccucguc gacggccucu     1740

ggggccaggg ccccuucuac gagaagaacc gccucaccug guucgacgag ggcaccgccg     1800

aguucuucgc cggcuccacc cgcaccuccg gcguccuccc ccgcaagucc auccucggcu     1860

accucgccaa ggacaagguc gaccaccgcu acucccucaa gaagacccuc aacuccggcu     1920

acgacgacuc cgacuggaug uucuacaacu acggcuucgc cgucgcccac uaccucuacg     1980

agaaggacau gcccaccuuc aucaagauga acaaggccau ccucaacacc gacgucaagu     2040

ccuacgacga gaucaucaag aagcucuccg acgacgccaa caagaacacc gaguaccaga     2100

accacaucca ggagcucgcc gacaaguacc agggcgccgg caucccccuc gucuccgacg     2160

acuaccucaa ggaccacggc uacaagaagg ccuccgaggu cuacuccgag aucuccaagg     2220

ccgccucccu caccaacacc uccgucaccg ccgagaaguc ccaguacuuc aacaccuuca     2280

cccuccgcgg caccuacacc ggcgagaccu ccaagggcga guucaaggac ugggacgaga     2340

uguccaagaa gcucgacggc acccucgagu cccucgccaa gaacuccugg uccggcuaca     2400

agacccucac cgccuacuuc accaacuacc gcgucaccuc cgacaacaag guccaguacg     2460

acgucgucuu ccacggcguc cucaccgaca acgccgacau cuccaacaac aaggccccca     2520

ucgccaaggu caccggcccc uccaccggcg ccgucggccg caacaucgag uucuccggca     2580

aggacuccaa ggacgaggac ggcaagaucg ucuccuacga cugggacuuc ggcgacggcg     2640

ccaccucccg cggcaagaac uccguccacg ccuacaagaa ggccggcacc uacaacguca     2700

cccucaaggu caccgacgac aagggcgcca ccgccaccga guccuucacc aucgagauca     2760

agaacgagga caccaccacc cccaucacca aggagaugga gcccaacgac gacaucaagg     2820

aggccaacgg ccccaucguc gagggcguca ccgucaaggg cgaccucaac ggcuccgacg     2880

acgccgacac cuucuacuuc gacgucaagg aggacggcga cgucaccauc gagcuccccu     2940

acuccggcuc cuccaacuuc accuggcucg ucuacaagga gggcgacgac cagaaccaca     3000

ucgccuccgg caucgacaag aacaacucca aggucggcac cuucaagucc accaagggcc     3060

gccacuacgu cuucaucuac aagcacgacu ccgccuccaa caucuccuac ucccucaaca     3120

ucaagggccu cggcaacgag aagcucaagg agaaggagaa caacgacucc uccgacaagg     3180

ccaccgucau ccccaacuuc aacaccacca ugcagggcuc ccuccucggc gacgacuccc     3240

gcgacuacua cuccuucgag gucaaggagg agggcgaggu caacaucgag cucgacaaga     3300

aggacgaguu cggcgucacc uggacccucc accccgaguc caacaucaac gaccgcauca     3360

ccuacggcca ggucgacggc aacaaggucu ccaacaaggu caagcuccgc cccggcaagu     3420

acuaccuccu cgucuacaag uacuccggcu ccggcaacua cgagcuccgc gucaacaagu     3480

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  2791
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt2)

<400>  2791
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccucaagau cauccucaac cgcggcaaga ccaugaagcg caagugccuc uccaagcgcc      120

ucaugcucgc caucaccaug gccaccaucu ucaccgucaa cuccacccuc cccaucuacg      180

ccgccgucga caagaacaac gccaccgccg ccguccagaa cgaguccaag cgcuacaccg      240

ucuccuaccu caagacccuc aacuacuacg accucgucga ccuccucguc aagaccgaga      300

ucgagaaccu ccccgaccuc uuccaguacu ccuccgacgc caaggaguuc uacggcaaca      360

agacccgcau guccuucauc auggacgaga ucggccgccg cgccccccag uacaccgaga      420

ucgaccacaa gggcaucccc acccucgucg aggucguccg cgccggcuuc uaccucggcu      480

uccacaacaa ggagcucaac gagaucaaca agcgcuccuu caaggagcgc gucauccccu      540

ccauccucgc cauccagaag aaccccaacu ucaagcucgg caccgagguc caggacaaga      600

ucgucuccgc caccggccuc cucgccggca acgagaccgc cccccccgag gucgucaaca      660

acuucacccc cauccuccag gacugcauca agaacaucga ccgcuacgcc cucgacgacc      720

ucaaguccaa ggcccucuuc aacguccucg ccgcccccac cuacgacauc accgaguacc      780

uccgcgccac caaggagaag cccgagaaca cccccuggua cggcaagauc gacggcuuca      840

ucaacgagcu caagaagcuc gcccucuacg gcaagaucaa cgacaacaac uccuggauca      900

ucgacaacgg caucuaccac aucgcccccc ucggcaagcu ccacuccaac aacaagaucg      960

gcaucgagac ccucaccgag gucaugaagg ucuaccccua ccucuccaug cagcaccucc     1020

aguccgccga ccagaucaag cgccacuacg acuccaagga cgccgagggc aacaagaucc     1080

cccucgacaa guucaagaag gagggcaagg agaaguacug ccccaagacc uacaccuucg     1140

acgacggcaa ggucaucauc aaggccggcg cccgcgucga ggaggagaag gucaagcgcc     1200

ucuacugggc cuccaaggag gucaacuccc aguucuuccg cgucuacggc aucgacaagc     1260

cccucgagga gggcaacccc gacgacaucc ucaccauggu caucuacaac ucccccgagg     1320

aguacaagcu caacuccguc cucuacggcu acgacaccaa caacggcggc auguacaucg     1380

agcccgaggg caccuucuuc accuacgagc gcgaggccca ggaguccacc uacacccucg     1440

aggagcucuu ccgccacgag uacacccacu accuccaggg ccgcuacgcc guccccggcc     1500

aguggggccg caccaagcuc uacgacaacg accgccucac cugguacgag gagggcggcg     1560

ccgagcucuu cgccggcucc acccgcaccu ccggcauccu cccccgcaag uccaucgucu     1620

ccaacaucca caacaccacc cgcaacaacc gcuacaagcu cuccgacacc guccacucca     1680

aguacggcgc cuccuucgag uucuacaacu acgccugcau guucauggac uacauguaca     1740

acaaggacau gggcauccuc aacaagcuca acgaccucgc caagaacaac gacgucgacg     1800

gcuacgacaa cuacauccgc gaccucuccu ccaacuacgc ccucaacgac aaguaccagg     1860

accacaugca ggagcgcauc gacaacuacg agaaccucac cguccccuuc gucgccgacg     1920

acuaccucgu ccgccacgcc uacaagaacc ccaacgagau cuacuccgag aucuccgagg     1980

ucgccaagcu caaggacgcc aaguccgagg ucaagaaguc ccaguacuuc uccaccuuca     2040

cccuccgcgg cuccuacacc ggcggcgccu ccaagggcaa gcucgaggac cagaaggcca     2100

ugaacaaguu caucgacgac ucccucaaga agcucgacac cuacuccugg uccggcuaca     2160

agacccucac cgccuacuuc accaacuaca aggucgacuc cuccaaccgc gucaccuacg     2220

acgucgucuu ccacggcuac cuccccaacg agggcgacuc caagaacucc cuccccuacg     2280

gcaagaucaa cggcaccuac aagggcaccg agaaggagaa gaucaaguuc uccuccgagg     2340

gcuccuucga ccccgacggc aagaucgucu ccuacgagug ggacuucggc gacggcaaca     2400

aguccaacga ggagaacccc gagcacuccu acgacaaggu cggcaccuac accgucaagc     2460

ucaaggucac cgacgacaag ggcgaguccu ccgucuccac caccaccgcc gagaucaagg     2520

accucuccga gaacaagcuc cccgucaucu acaugcacgu ccccaagucc ggcgcccuca     2580

accagaaggu cgucuucuac ggcaagggca ccuacgaccc cgacggcucc aucgccggcu     2640

accaguggga cuucggcgac ggcuccgacu ucuccuccga gcagaacccc ucccacgucu     2700

acaccaagaa gggcgaguac accgucaccc uccgcgucau ggacuccucc ggccagaugu     2760

ccgagaagac caugaagauc aagaucaccg accccgucua ccccaucggc accgagaagg     2820

agcccaacaa cuccaaggag accgccuccg gccccaucgu ccccggcauc cccgucuccg     2880

gcaccaucga gaacaccucc gaccaggacu acuucuacuu cgacgucauc acccccggcg     2940

aggucaagau cgacaucaac aagcucggcu acggcggcgc caccuggguc gucuacgacg     3000

agaacaacaa cgccgucucc uacgccaccg acgacggcca gaaccucucc ggcaaguuca     3060

aggccgacaa gcccggccgc uacuacaucc accucuacau guucaacggc uccuacaugc     3120

ccuaccgcau caacaucgag ggcuccgucg gccgcugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  2792
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt2)

<400>  2792
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

gcaagugccu cuccaagcgc cucaugcucg ccaucaccau ggccaccauc uucaccguca      120

acuccacccu ccccaucuac gccgccgucg acaagaacaa cgccaccgcc gccguccaga      180

acgaguccaa gcgcuacacc gucuccuacc ucaagacccu caacuacuac gaccucgucg      240

accuccucgu caagaccgag aucgagaacc uccccgaccu cuuccaguac uccuccgacg      300

ccaaggaguu cuacggcaac aagacccgca uguccuucau cauggacgag aucggccgcc      360

gcgcccccca guacaccgag aucgaccaca agggcauccc cacccucguc gaggucgucc      420

gcgccggcuu cuaccucggc uuccacaaca aggagcucaa cgagaucaac aagcgcuccu      480

ucaaggagcg cgucaucccc uccauccucg ccauccagaa gaaccccaac uucaagcucg      540

gcaccgaggu ccaggacaag aucgucuccg ccaccggccu ccucgccggc aacgagaccg      600

ccccccccga ggucgucaac aacuucaccc ccauccucca ggacugcauc aagaacaucg      660

accgcuacgc ccucgacgac cucaagucca aggcccucuu caacguccuc gccgccccca      720

ccuacgacau caccgaguac cuccgcgcca ccaaggagaa gcccgagaac acccccuggu      780

acggcaagau cgacggcuuc aucaacgagc ucaagaagcu cgcccucuac ggcaagauca      840

acgacaacaa cuccuggauc aucgacaacg gcaucuacca caucgccccc cucggcaagc      900

uccacuccaa caacaagauc ggcaucgaga cccucaccga ggucaugaag gucuaccccu      960

accucuccau gcagcaccuc caguccgccg accagaucaa gcgccacuac gacuccaagg     1020

acgccgaggg caacaagauc ccccucgaca aguucaagaa ggagggcaag gagaaguacu     1080

gccccaagac cuacaccuuc gacgacggca aggucaucau caaggccggc gcccgcgucg     1140

aggaggagaa ggucaagcgc cucuacuggg ccuccaagga ggucaacucc caguucuucc     1200

gcgucuacgg caucgacaag ccccucgagg agggcaaccc cgacgacauc cucaccaugg     1260

ucaucuacaa cucccccgag gaguacaagc ucaacuccgu ccucuacggc uacgacacca     1320

acaacggcgg cauguacauc gagcccgagg gcaccuucuu caccuacgag cgcgaggccc     1380

aggaguccac cuacacccuc gaggagcucu uccgccacga guacacccac uaccuccagg     1440

gccgcuacgc cguccccggc caguggggcc gcaccaagcu cuacgacaac gaccgccuca     1500

ccugguacga ggagggcggc gccgagcucu ucgccggcuc cacccgcacc uccggcaucc     1560

ucccccgcaa guccaucguc uccaacaucc acaacaccac ccgcaacaac cgcuacaagc     1620

ucuccgacac cguccacucc aaguacggcg ccuccuucga guucuacaac uacgccugca     1680

uguucaugga cuacauguac aacaaggaca ugggcauccu caacaagcuc aacgaccucg     1740

ccaagaacaa cgacgucgac ggcuacgaca acuacauccg cgaccucucc uccaacuacg     1800

cccucaacga caaguaccag gaccacaugc aggagcgcau cgacaacuac gagaaccuca     1860

ccguccccuu cgucgccgac gacuaccucg uccgccacgc cuacaagaac cccaacgaga     1920

ucuacuccga gaucuccgag gucgccaagc ucaaggacgc caaguccgag gucaagaagu     1980

cccaguacuu cuccaccuuc acccuccgcg gcuccuacac cggcggcgcc uccaagggca     2040

agcucgagga ccagaaggcc augaacaagu ucaucgacga cucccucaag aagcucgaca     2100

ccuacuccug guccggcuac aagacccuca ccgccuacuu caccaacuac aaggucgacu     2160

ccuccaaccg cgucaccuac gacgucgucu uccacggcua ccuccccaac gagggcgacu     2220

ccaagaacuc ccuccccuac ggcaagauca acggcaccua caagggcacc gagaaggaga     2280

agaucaaguu cuccuccgag ggcuccuucg accccgacgg caagaucguc uccuacgagu     2340

gggacuucgg cgacggcaac aaguccaacg aggagaaccc cgagcacucc uacgacaagg     2400

ucggcaccua caccgucaag cucaagguca ccgacgacaa gggcgagucc uccgucucca     2460

ccaccaccgc cgagaucaag gaccucuccg agaacaagcu ccccgucauc uacaugcacg     2520

uccccaaguc cggcgcccuc aaccagaagg ucgucuucua cggcaagggc accuacgacc     2580

ccgacggcuc caucgccggc uaccaguggg acuucggcga cggcuccgac uucuccuccg     2640

agcagaaccc cucccacguc uacaccaaga agggcgagua caccgucacc cuccgcguca     2700

uggacuccuc cggccagaug uccgagaaga ccaugaagau caagaucacc gaccccgucu     2760

accccaucgg caccgagaag gagcccaaca acuccaagga gaccgccucc ggccccaucg     2820

uccccggcau ccccgucucc ggcaccaucg agaacaccuc cgaccaggac uacuucuacu     2880

ucgacgucau cacccccggc gaggucaaga ucgacaucaa caagcucggc uacggcggcg     2940

ccaccugggu cgucuacgac gagaacaaca acgccgucuc cuacgccacc gacgacggcc     3000

agaaccucuc cggcaaguuc aaggccgaca agcccggccg cuacuacauc caccucuaca     3060

uguucaacgg cuccuacaug cccuaccgca ucaacaucga gggcuccguc ggccgcugag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  2793
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt2)

<400>  2793
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggucaccuu caucucccuc cucuuccucu ucuccuccgc cuacuccguc cagaacgagu      120

ccaagcgcua caccgucucc uaccucaaga cccucaacua cuacgaccuc gucgaccucc      180

ucgucaagac cgagaucgag aaccuccccg accucuucca guacuccucc gacgccaagg      240

aguucuacgg caacaagacc cgcauguccu ucaucaugga cgagaucggc cgccgcgccc      300

cccaguacac cgagaucgac cacaagggca uccccacccu cgucgagguc guccgcgccg      360

gcuucuaccu cggcuuccac aacaaggagc ucaacgagau caacaagcgc uccuucaagg      420

agcgcgucau ccccuccauc cucgccaucc agaagaaccc caacuucaag cucggcaccg      480

agguccagga caagaucguc uccgccaccg gccuccucgc cggcaacgag accgcccccc      540

ccgaggucgu caacaacuuc acccccaucc uccaggacug caucaagaac aucgaccgcu      600

acgcccucga cgaccucaag uccaaggccc ucuucaacgu ccucgccgcc cccaccuacg      660

acaucaccga guaccuccgc gccaccaagg agaagcccga gaacaccccc ugguacggca      720

agaucgacgg cuucaucaac gagcucaaga agcucgcccu cuacggcaag aucaacgaca      780

acaacuccug gaucaucgac aacggcaucu accacaucgc cccccucggc aagcuccacu      840

ccaacaacaa gaucggcauc gagacccuca ccgaggucau gaaggucuac cccuaccucu      900

ccaugcagca ccuccagucc gccgaccaga ucaagcgcca cuacgacucc aaggacgccg      960

agggcaacaa gaucccccuc gacaaguuca agaaggaggg caaggagaag uacugcccca     1020

agaccuacac cuucgacgac ggcaagguca ucaucaaggc cggcgcccgc gucgaggagg     1080

agaaggucaa gcgccucuac ugggccucca aggaggucaa cucccaguuc uuccgcgucu     1140

acggcaucga caagccccuc gaggagggca accccgacga cauccucacc auggucaucu     1200

acaacucccc cgaggaguac aagcucaacu ccguccucua cggcuacgac accaacaacg     1260

gcggcaugua caucgagccc gagggcaccu ucuucaccua cgagcgcgag gcccaggagu     1320

ccaccuacac ccucgaggag cucuuccgcc acgaguacac ccacuaccuc cagggccgcu     1380

acgccguccc cggccagugg ggccgcacca agcucuacga caacgaccgc cucaccuggu     1440

acgaggaggg cggcgccgag cucuucgccg gcuccacccg caccuccggc auccuccccc     1500

gcaaguccau cgucuccaac auccacaaca ccacccgcaa caaccgcuac aagcucuccg     1560

acaccgucca cuccaaguac ggcgccuccu ucgaguucua caacuacgcc ugcauguuca     1620

uggacuacau guacaacaag gacaugggca uccucaacaa gcucaacgac cucgccaaga     1680

acaacgacgu cgacggcuac gacaacuaca uccgcgaccu cuccuccaac uacgcccuca     1740

acgacaagua ccaggaccac augcaggagc gcaucgacaa cuacgagaac cucaccgucc     1800

ccuucgucgc cgacgacuac cucguccgcc acgccuacaa gaaccccaac gagaucuacu     1860

ccgagaucuc cgaggucgcc aagcucaagg acgccaaguc cgaggucaag aagucccagu     1920

acuucuccac cuucacccuc cgcggcuccu acaccggcgg cgccuccaag ggcaagcucg     1980

aggaccagaa ggccaugaac aaguucaucg acgacucccu caagaagcuc gacaccuacu     2040

ccugguccgg cuacaagacc cucaccgccu acuucaccaa cuacaagguc gacuccucca     2100

accgcgucac cuacgacguc gucuuccacg gcuaccuccc caacgagggc gacuccaaga     2160

acucccuccc cuacggcaag aucaacggca ccuacaaggg caccgagaag gagaagauca     2220

aguucuccuc cgagggcucc uucgaccccg acggcaagau cgucuccuac gagugggacu     2280

ucggcgacgg caacaagucc aacgaggaga accccgagca cuccuacgac aaggucggca     2340

ccuacaccgu caagcucaag gucaccgacg acaagggcga guccuccguc uccaccacca     2400

ccgccgagau caaggaccuc uccgagaaca agcuccccgu caucuacaug cacgucccca     2460

aguccggcgc ccucaaccag aaggucgucu ucuacggcaa gggcaccuac gaccccgacg     2520

gcuccaucgc cggcuaccag ugggacuucg gcgacggcuc cgacuucucc uccgagcaga     2580

accccuccca cgucuacacc aagaagggcg aguacaccgu cacccuccgc gucauggacu     2640

ccuccggcca gauguccgag aagaccauga agaucaagau caccgacccc gucuacccca     2700

ucggcaccga gaaggagccc aacaacucca aggagaccgc cuccggcccc aucguccccg     2760

gcauccccgu cuccggcacc aucgagaaca ccuccgacca ggacuacuuc uacuucgacg     2820

ucaucacccc cggcgagguc aagaucgaca ucaacaagcu cggcuacggc ggcgccaccu     2880

gggucgucua cgacgagaac aacaacgccg ucuccuacgc caccgacgac ggccagaacc     2940

ucuccggcaa guucaaggcc gacaagcccg gccgcuacua cauccaccuc uacauguuca     3000

acggcuccua caugcccuac cgcaucaaca ucgagggcuc cgucggccgc ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  2794
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt2)

<400>  2794
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggucaccuu caucucccuc cucuuccucu ucuccuccgc cuacuccaug aagcgcaagu      120

gccucuccaa gcgccucaug cucgccauca ccauggccac caucuucacc gucaacucca      180

cccuccccau cuacgccgcc gucgacaaga acaacgccac cgccgcccgc cgccgccgca      240

agcgcgucca gaacgagucc aagcgcuaca ccgucuccua ccucaagacc cucaacuacu      300

acgaccucgu cgaccuccuc gucaagaccg agaucgagaa ccuccccgac cucuuccagu      360

acuccuccga cgccaaggag uucuacggca acaagacccg cauguccuuc aucauggacg      420

agaucggccg ccgcgccccc caguacaccg agaucgacca caagggcauc cccacccucg      480

ucgaggucgu ccgcgccggc uucuaccucg gcuuccacaa caaggagcuc aacgagauca      540

acaagcgcuc cuucaaggag cgcgucaucc ccuccauccu cgccauccag aagaacccca      600

acuucaagcu cggcaccgag guccaggaca agaucgucuc cgccaccggc cuccucgccg      660

gcaacgagac cgcccccccc gaggucguca acaacuucac ccccauccuc caggacugca      720

ucaagaacau cgaccgcuac gcccucgacg accucaaguc caaggcccuc uucaacgucc      780

ucgccgcccc caccuacgac aucaccgagu accuccgcgc caccaaggag aagcccgaga      840

acacccccug guacggcaag aucgacggcu ucaucaacga gcucaagaag cucgcccucu      900

acggcaagau caacgacaac aacuccugga ucaucgacaa cggcaucuac cacaucgccc      960

cccucggcaa gcuccacucc aacaacaaga ucggcaucga gacccucacc gaggucauga     1020

aggucuaccc cuaccucucc augcagcacc uccaguccgc cgaccagauc aagcgccacu     1080

acgacuccaa ggacgccgag ggcaacaaga ucccccucga caaguucaag aaggagggca     1140

aggagaagua cugccccaag accuacaccu ucgacgacgg caaggucauc aucaaggccg     1200

gcgcccgcgu cgaggaggag aaggucaagc gccucuacug ggccuccaag gaggucaacu     1260

cccaguucuu ccgcgucuac ggcaucgaca agccccucga ggagggcaac cccgacgaca     1320

uccucaccau ggucaucuac aacucccccg aggaguacaa gcucaacucc guccucuacg     1380

gcuacgacac caacaacggc ggcauguaca ucgagcccga gggcaccuuc uucaccuacg     1440

agcgcgaggc ccaggagucc accuacaccc ucgaggagcu cuuccgccac gaguacaccc     1500

acuaccucca gggccgcuac gccguccccg gccagugggg ccgcaccaag cucuacgaca     1560

acgaccgccu caccugguac gaggagggcg gcgccgagcu cuucgccggc uccacccgca     1620

ccuccggcau ccucccccgc aaguccaucg ucuccaacau ccacaacacc acccgcaaca     1680

accgcuacaa gcucuccgac accguccacu ccaaguacgg cgccuccuuc gaguucuaca     1740

acuacgccug cauguucaug gacuacaugu acaacaagga caugggcauc cucaacaagc     1800

ucaacgaccu cgccaagaac aacgacgucg acggcuacga caacuacauc cgcgaccucu     1860

ccuccaacua cgcccucaac gacaaguacc aggaccacau gcaggagcgc aucgacaacu     1920

acgagaaccu caccgucccc uucgucgccg acgacuaccu cguccgccac gccuacaaga     1980

accccaacga gaucuacucc gagaucuccg aggucgccaa gcucaaggac gccaaguccg     2040

aggucaagaa gucccaguac uucuccaccu ucacccuccg cggcuccuac accggcggcg     2100

ccuccaaggg caagcucgag gaccagaagg ccaugaacaa guucaucgac gacucccuca     2160

agaagcucga caccuacucc ugguccggcu acaagacccu caccgccuac uucaccaacu     2220

acaaggucga cuccuccaac cgcgucaccu acgacgucgu cuuccacggc uaccucccca     2280

acgagggcga cuccaagaac ucccuccccu acggcaagau caacggcacc uacaagggca     2340

ccgagaagga gaagaucaag uucuccuccg agggcuccuu cgaccccgac ggcaagaucg     2400

ucuccuacga gugggacuuc ggcgacggca acaaguccaa cgaggagaac cccgagcacu     2460

ccuacgacaa ggucggcacc uacaccguca agcucaaggu caccgacgac aagggcgagu     2520

ccuccgucuc caccaccacc gccgagauca aggaccucuc cgagaacaag cuccccguca     2580

ucuacaugca cguccccaag uccggcgccc ucaaccagaa ggucgucuuc uacggcaagg     2640

gcaccuacga ccccgacggc uccaucgccg gcuaccagug ggacuucggc gacggcuccg     2700

acuucuccuc cgagcagaac cccucccacg ucuacaccaa gaagggcgag uacaccguca     2760

cccuccgcgu cauggacucc uccggccaga uguccgagaa gaccaugaag aucaagauca     2820

ccgaccccgu cuaccccauc ggcaccgaga aggagcccaa caacuccaag gagaccgccu     2880

ccggccccau cguccccggc auccccgucu ccggcaccau cgagaacacc uccgaccagg     2940

acuacuucua cuucgacguc aucacccccg gcgaggucaa gaucgacauc aacaagcucg     3000

gcuacggcgg cgccaccugg gucgucuacg acgagaacaa caacgccguc uccuacgcca     3060

ccgacgacgg ccagaaccuc uccggcaagu ucaaggccga caagcccggc cgcuacuaca     3120

uccaccucua cauguucaac ggcuccuaca ugcccuaccg caucaacauc gagggcuccg     3180

ucggccgcug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  2795
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt2)

<400>  2795
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cuccucggcg ccgccuucgc caugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgagguccu caccccccuc aagugguacc      180

aguccauccg cccccccuac cccuccuacg gcuacgagcc caugggcggc uggcuccacc      240

accagaucau ccccguccuc ucccagcagc acccccccac ccacacccuc cagccccacc      300

accacauccc cgucgucccc gcccagcagc ccgucauccc ccagcagccc augaugcccg      360

uccccggcca gcacuccaug acccccaucc agcaccacca gcccaaccuc cccccccccg      420

cccagcagcc cuaccagccc cagcccgucc agccccagcc ccaccagccc augcagcccc      480

agccccccgu ccaccccaug cagccccucc ccccccagcc cccccucccc cccauguucc      540

ccaugcagcc ccuccccccc augcuccccg accucacccu cgaggccugg cccuccaccg      600

acaagaccaa gcgcgaggag gucgacugag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  2796
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt2)

<400>  2796
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc cucacccccc      120

ucaaguggua ccaguccauc cgcccccccu accccuccua cggcuacgag cccaugggcg      180

gcuggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  2797
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt2)

<400>  2797
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc cucacccccc      120

ucaaguggua ccaguccauc cgcccccccc ccaugcuccc cgaccucacc cucgaggccu      180

ggcccuccac cgacaagacc aagcgcgagg aggucgacug aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  2798
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt2)

<400>  2798
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc ccgcacccuc guccuccucc ucuccggcgc ccucgcccuc acccagaccu      120

gggccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagucca uccgcccccc cuaccccucc uacggcuacg      240

agcccauggg cggcugguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  2799
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt2)

<400>  2799
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc ccgcacccuc guccuccucc ucuccggcgc ccucgcccuc acccagaccu      120

gggccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagucca uccgcccccc ccccaugcuc cccgaccuca      240

cccucgaggc cuggcccucc accgacaaga ccaagcgcga ggaggucgac ugaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  2800
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt2)

<400>  2800
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cucgucggcg ccgccuucgc caugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgagguccu caccccccuc aagugguacc      180

aguccaugau ccgccccccc uacuccuccu acggcuacga gcccaugggc ggcuggcucc      240

accaccagau cauccccguc gucucccagc agcacccccu cacccacacc cuccaguccc      300

accaccacau ccccgucguc cccgcccagc agccccgcgu ccgccagcag gcccucaugc      360

ccguccccgg ccagcagucc augaccccca cccagcacca ccagcccaac cucccccucc      420

ccgcccagca gcccuuccag ccccagcccg uccagcccca gccccaccag cccaugcagc      480

cccagccccc cguccagccc augcagcccc uccuccccca gcccccccuc ccccccaugu      540

ucccccuccg cccccucccc cccauccucc ccgaccucca ccucgaggcc uggcccgcca      600

ccgacaagac caagcaggag gaggucgacu gaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  2801
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt2)

<400>  2801
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc cucacccccc      120

ucaaguggua ccaguccaug auccgccccc ccuacuccuc cuacggcuac gagcccaugg      180

gcggcuggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  2802
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt2)

<400>  2802
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc cucacccccc      120

ucaaguggua ccaguccaug auccgccccc cccccauccu ccccgaccuc caccucgagg      180

ccuggcccgc caccgacaag accaagcagg aggaggucga cugaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  2803
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt2)

<400>  2803
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc ccgcacccuc guccuccucc ucuccggcgc ccucgcccuc acccagaccu      120

gggccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagucca ugauccgccc ccccuacucc uccuacggcu      240

acgagcccau gggcggcugg ugaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  2804
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt2)

<400>  2804
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc ccgcacccuc guccuccucc ucuccggcgc ccucgcccuc acccagaccu      120

gggccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagucca ugauccgccc cccccccauc cuccccgacc      240

uccaccucga ggccuggccc gccaccgaca agaccaagca ggaggagguc gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  2805
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt2)

<400>  2805
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cuccucggcg ccgccuucuc caugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgagguccu caccccccuc aagugguacc      180

agaacaugau ccgccacccc uacaccuccu acggcuacga gcccaugggc ggcuggcucc      240

accaccagau cauccccguc gucucccagc agacccccca gucccacgcc cuccagcccc      300

accaccacau ccccaugguc cccgcccagc agcccggcau cccccagcag cccaugaugc      360

cccuccccgg ccagcacucc augaccccca cccagcacca ccagcccaac cucccccucc      420

ccgcccagca gcccuuccag ccccagcccg uccagcccca gccccaccag ccccuccagc      480

cccagucccc caugcacccc auccagcccc uccuccccca gcccccccuc ccccccaugu      540

ucuccaugca gucccuccuc cccgaccucc cccucgaggc cuggcccgcc accgacaaga      600

ccaagcgcga ggaggucgac ugaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  2806
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt2)

<400>  2806
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc cucacccccc      120

ucaaguggua ccagaacaug auccgccacc ccuacaccuc cuacggcuac gagcccaugg      180

gcggcuggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  2807
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt2)

<400>  2807
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc cucacccccc      120

ucaaguggua ccagaacaug auccgccacc ccucccuccu ccccgaccuc ccccucgagg      180

ccuggcccgc caccgacaag accaagcgcg aggaggucga cugaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  2808
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt2)

<400>  2808
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc ccgcacccuc guccuccucc ucuccggcgc ccucgcccuc acccagaccu      120

gggccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccuacacc uccuacggcu      240

acgagcccau gggcggcugg ugaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  2809
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt2)

<400>  2809
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc ccgcacccuc guccuccucc ucuccggcgc ccucgcccuc acccagaccu      120

gggccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccucccuc cuccccgacc      240

ucccccucga ggccuggccc gccaccgaca agaccaagcg cgaggagguc gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  2810
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt2)

<400>  2810
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cuccucggcg ccgccuucuc caugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acauccgcca ccccuacacc uccuacggcu      180

acgagcccau gggcggcugg cuccaccacc agaucauccc cgucgucucc cagcagaccc      240

cccaguccca cgcccuccag ccccaccacc acauccccau gguccccgcc cagcagcccg      300

gcauccccca gcagcccaug augccccucc ccggccagca cuccaugacc cccacccagc      360

accaccagcc caaccucccc cuccccgccc agcagcccuu ccagccccag cccguccagc      420

cccagcccca ccagccccuc cagccccagu cccccaugca ccccauccag ccccuccucc      480

cccagccccc ccuccccccc auguucucca ugcagucccu ccuccccgac cucccccucg      540

aggccuggcc cgccaccgac aagaccaagc gcgaggaggu cgacugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  2811
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt2)

<400>  2811
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggaucuu cuucgccugc cuccucggcg ccucccucgc caugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgagguccu caccccccuc aagugguacc      180

agaacaugau ccgccacccc uacaccuccu acggcuacga gcccaugggc ggcuggcucc      240

accaccagau cauccccguc gucucccagc agacccccca gucccacgcc cuccagcccc      300

accaccacau ccccaugguc cccgcccagc agcccggcau cccccagcag cccaugaugc      360

cccuccccgg ccagcacucc augaccccca cccagcacca ccagcccaac cucccccucc      420

ccgcccagca gcccuuccag ccccagcccg uccagcccca gccccaccag ccccuccagc      480

cccagucccc caugcacccc auccagcccc uccuccccca gcccccccuc ccccccaugu      540

ucuccaugca gucccuccuc cccgaccucc cccucgaggc cuggcccgcc accgacaaga      600

ccaagcgcga ggaggucgac ugaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  2812
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt2)

<400>  2812
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cuccucggcg ccgccuucuc caugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgagguccu caccccccuc aagugguacc      180

agaacaugau ccgccacccc ucccuccucc ccgaccuccc ccucgaggcc uggcccgcca      240

ccgacaagac caagcgcgag gaggucgacu gaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  2813
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt2)

<400>  2813
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cuccucggcg ccgccuucuc caugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgaggaccu cuaccucgag gccauccgca      180

ucgaccgcac cgccuucguc cucacccccc ucaaguggua ccagaacaug auccgccacc      240

ccuacaccuc cuacggcuac gagcccaugg gcggcuggcu ccaccaccag aucauccccg      300

ucgucuccca gcagaccccc cagucccacg cccuccagcc ccaccaccac auccccaugg      360

uccccgccca gcagcccggc aucccccagc agcccaugau gccccucccc ggccagcacu      420

ccaugacccc cacccagcac caccagccca accucccccu ccccgcccag cagcccuucc      480

agccccagcc cguccagccc cagccccacc agccccucca gccccagucc cccaugcacc      540

ccauccagcc ccuccucccc cagccccccc ucccccccau guucuccaug cagucccucc      600

uccccgaccu cccccucgag gccuggcccg ccaccgacaa gaccaagcgc gaggaggucg      660

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  2814
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt2)

<400>  2814
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cuccucggcg ccgccuucuc caugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgagguccu caccccccuc aagugguacc      180

agaacaugau ccgccacccc accccccagu cccacgcccu ccagccccac caccacaucc      240

ccaugguccc cgcccagcag cccggcaucc cccagcagcc caugaugccc cuccccggcc      300

agcacuccau gacccccacc cagcaccacc agcccaaccu cccccucccc gcccagcagc      360

ccuuccagcc ccagcccguc cagccccagc cccaccagcc ccuccagccc caguccccca      420

ugcaccccau ccagccccuc cucccccagc ccccccuccc ccccauguuc uccaugcagu      480

cccuccuccc cgaccucccc cucgaggccu ggcccgccac cgacaagacc aagcgcgagg      540

aggucgacug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  2815
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt2)

<400>  2815
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgagguc cucacccccc      120

ucaaguggua ccagaacaug auccgccacc ccuacaccuc cuacggcuac gagcccaugg      180

gcggcuggcu ccaccaccag aucauccccg ucgucuccca gcagaccccc cagucccacg      240

cccuccagcc ccaccaccac auccccaugg uccccgccca gcagcccggc aucccccagc      300

agcccaugau gccccucccc ggccagcacu ccaugacccc cacccagcac caccagccca      360

accucccccu ccccgcccag cagcccuucc agccccagcc cguccagccc cagccccacc      420

agccccucca gccccagucc cccaugcacc ccauccagcc ccuccucccc cagccccccc      480

ucccccccau guucuccaug cagucccucc uccccgaccu cccccucgag gccuggcccg      540

ccaccgacaa gaccaagcgc gaggaggucg acugaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  2816
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt2)

<400>  2816
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gcgucgcccg ccucccccuc cuccucggcc uccuccuccu cccccgcccc ggccgccccc      120

ucgaccucgc cgacuacacc uacgaccucg ccgaggagga cgacuccgag ccccucaacu      180

acaaggaccc cugcaaggcc gccgccuucc ucggcgacau cgcccucgac gaggaggacc      240

uccgcgccuu ccagguccag caggccgucg accuccgccg ccacaccgcc cgcaaguccu      300

ccaucaaggc cgccgucccc ggcaacaccu ccacccccuc cugccagucc accaacggcc      360

agccccagcg cggcgccugc ggccgcuggc gcggccgcuc ccgcucccgc cgcgccgcca      420

ccucccgccc cgagcgcguc uggcccgacg gcgucauccc cuucgucauc ggcggcaacu      480

ucaccggcuc ccagcgcgcc gucuuccgcc aggccaugcg ccacugggag aagcacaccu      540

gcgucaccuu ccucgagcgc accgacgagg acuccuacau cgucuucacc uaccgccccu      600

gcggcugcug cuccuacguc ggccgccgcg gcggcggccc ccaggccauc uccaucggca      660

agaacugcga caaguucggc aucgucgucc acgagcucgg ccacgucguc ggcuucuggc      720

acgagcacac ccgccccgac cgcgaccgcc acgucuccau cguccgcgag aacauccagc      780

ccggccagga guacaacuuc cucaagaugg agccccagga ggucgagucc cucggcgaga      840

ccuacgacuu cgacuccauc augcacuacg cccgcaacac cuucucccgc ggcaucuucc      900

ucgacaccau cguccccaag uacgagguca acggcgucaa gccccccauc ggccagcgca      960

cccgccucuc caagggcgac aucgcccagg cccgcaagcu cuacaagugc cccgccugcg     1020

gcgagacccu ccaggacucc accggcaacu ucuccucccc cgaguacccc aacggcuacu     1080

ccgcccacau gcacugcguc uggcgcaucu ccgucacccc cggcgagaag aucauccuca     1140

acuucaccuc ccucgaccuc uaccgcuccc gccucugcug guacgacuac gucgaggucc     1200

gcgacggcuu cuggcgcaag gccccccucc gcggccgcuu cugcggcucc aagcuccccg     1260

agcccaucgu cuccaccgac ucccgccucu gggucgaguu ccgcuccucc uccaacuggg     1320

ucggcaaggg cuucuucgcc gucuacgagg ccaucugcgg cggcgacguc aagaaggacu     1380

acggccacau ccaguccccc aacuaccccg acgacuaccg ccccuccaag gucugcaucu     1440

ggcgcaucca ggucuccgag ggcuuccacg ucggccucac cuuccagucc uucgagaucg     1500

agcgccacga cuccugcgcc uacgacuacc ucgagguccg cgacggccac uccgaguccu     1560

ccacccucau cggccgcuac ugcggcuacg agaagcccga cgacaucaag uccaccuccu     1620

cccgccucug gcucaaguuc gucuccgacg gcuccaucaa caaggccggc uucgccguca     1680

acuucuucaa ggaggucgac gagugcuccc gccccaaccg cggcggcugc gagcagcgcu     1740

gccucaacac ccucggcucc uacaagugcu ccugcgaccc cggcuacgag cucgcccccg     1800

acaagcgccg cugcgaggcc gccugcggcg gcuuccucac caagcucaac ggcuccauca     1860

ccucccccgg cuggcccaag gaguaccccc ccaacaagaa cugcaucugg cagcucgucg     1920

cccccaccca guaccgcauc ucccuccagu ucgacuucuu cgagaccgag ggcaacgacg     1980

ucugcaagua cgacuucguc gagguccgcu ccggccucac cgccgacucc aagcuccacg     2040

gcaaguucug cggcuccgag aagcccgagg ucaucaccuc ccaguacaac aacaugcgcg     2100

ucgaguucaa guccgacaac accgucucca agaagggcuu caaggcccac uucuucuccg     2160

acaaggacga gugcuccaag gacaacggcg gcugccagca ggacugcguc aacaccuucg     2220

gcuccuacga gugccagugc cgcuccggcu ucguccucca cgacaacaag cacgacugca     2280

aggaggccgg cugcgaccac aaggucaccu ccaccuccgg caccaucacc ucccccaacu     2340

ggcccgacaa guaccccucc aagaaggagu gcaccugggc caucuccucc acccccggcc     2400

accgcgucaa gcucaccuuc auggagaugg acaucgaguc ccagcccgag ugcgccuacg     2460

accaccucga ggucuucgac ggccgcgacg ccaaggcccc cguccucggc cgcuucugcg     2520

gcuccaagaa gcccgagccc guccucgcca ccggcucccg cauguuccuc cgcuucuacu     2580

ccgacaacuc cguccagcgc aagggcuucc aggccuccca cgccaccgag ugcggcggcc     2640

agguccgcgc cgacgucaag accaaggacc ucuacuccca cgcccaguuc ggcgacaaca     2700

acuaccccgg cggcgucgac ugcgaguggg ucaucgucgc cgaggagggc uacggcgucg     2760

agcucgucuu ccagaccuuc gaggucgagg aggagaccga cugcggcuac gacuacaugg     2820

agcucuucga cggcuacgac uccaccgccc cccgccucgg ccgcuacugc ggcuccggcc     2880

cccccgagga ggucuacucc gccggcgacu ccguccucgu caaguuccac uccgacgaca     2940

ccaucaccaa gaagggcuuc caccuccgcu acaccuccac caaguuccag gacacccucc     3000

acucccgcaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  2817
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt2)

<400>  2817
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucg       60

ccggcacccg cugccuccuc gcccuccucc ucccccaggu ccuccucggc ggcgccgccg      120

gccucguccc cgagcucggc cgccgcaagu ucgccgccgc cuccuccggc cgccccuccu      180

cccagcccuc cgacgagguc cucuccgagu ucgagcuccg ccuccucucc auguucggcc      240

ucaagcagcg ccccaccccc ucccgcgacg ccgucguccc ccccuacaug cucgaccucu      300

accgccgcca cuccggccag cccggcuccc ccgcccccga ccaccgccuc gagcgcgccg      360

ccucccgcgc caacaccguc cgcuccuucc accacgagga gucccucgag gagcuccccg      420

agaccuccgg caagaccacc cgccgcuucu ucuucaaccu cuccuccauc cccaccgagg      480

aguucaucac cuccgccgag cuccaggucu uccgcgagca gaugcaggac gcccucggca      540

acaacuccuc cuuccaccac cgcaucaaca ucuacgagau caucaagccc gccaccgcca      600

acuccaaguu ccccgucacc cgccuccucg acacccgccu cgucaaccag aacgccuccc      660

gcugggaguc cuucgacguc acccccgccg ucaugcgcug gaccgcccag ggccacgcca      720

accacggcuu cgucgucgag gucgcccacc ucgaggagaa gcagggcguc uccaagcgcc      780

acguccgcau cucccgcucc cuccaccagg acgagcacuc cuggucccag auccgccccc      840

uccucgucac cuucggccac gacggcaagg gccacccccu ccacaagcgc gagaagcgcc      900

aggccaagca caagcagcgc aagcgccuca aguccuccug caagcgccac ccccucuacg      960

ucgacuucuc cgacgucggc uggaacgacu ggaucgucgc cccccccggc uaccacgccu     1020

ucuacugcca cggcgagugc cccuuccccc ucgccgacca ccucaacucc accaaccacg     1080

ccaucgucca gacccucguc aacuccguca acuccaagau ccccaaggcc ugcugcgucc     1140

ccaccgagcu cuccgccauc uccaugcucu accucgacga gaacgagaag gucguccuca     1200

agaacuacca ggacaugguc gucgagggcu gcggcugccg cugaggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  2818
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt2)

<400>  2818
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaucc       60

ccggcaaccg caugcucaug gucguccucc ucugccaggu ccuccucggc ggcgccuccc      120

acgccucccu cauccccgag accggcaaga agaaggucgc cgagauccag ggccacgccg      180

gcggccgccg cuccggccag ucccacgagc uccuccgcga cuucgaggcc acccuccucc      240

agauguucgg ccuccgccgc cgcccccagc ccuccaaguc cgccgucauc cccgacuaca      300

ugcgcgaccu cuaccgccuc caguccggcg aggaggagga ggagcagauc cacuccaccg      360

gccucgagua ccccgagcgc cccgccuccc gcgccaacac cguccgcucc uuccaccacg      420

aggagcaccu cgagaacauc cccggcaccu ccgagaacuc cgccuuccgc uuccucuuca      480

accucuccuc cauccccgag aacgagguca ucuccuccgc cgagcuccgc cucuuccgcg      540

agcaggucga ccagggcccc gacugggagc gcggcuucca ccgcaucaac aucuacgagg      600

ucaugaagcc ccccgccgag gucguccccg gccaccucau cacccgccuc cucgacaccc      660

gccucgucca ccacaacguc acccgcuggg agaccuucga cgucuccccc gccguccucc      720

gcuggacccg cgagaagcag cccaacuacg gccucgccau cgaggucacc caccuccacc      780

agacccgcac ccaccagggc cagcacgucc gcaucucccg cucccucccc cagggcuccg      840

gcaacugggc ccagcuccgc ccccuccucg ucaccuucgg ccacgacggc cgcggccacg      900

cccucacccg ccgccgccgc gccaagcgcu cccccaagca ccacucccag cgcgcccgca      960

agaagaacaa gaacugccgc cgccacuccc ucuacgucga cuucuccgac gucggcugga     1020

acgacuggau cgucgccccc cccggcuacc aggccuucua cugccacggc gacugccccu     1080

ucccccucgc cgaccaccuc aacuccacca accacgccau cguccagacc cucgucaacu     1140

ccgucaacuc cuccaucccc aaggccugcu gcguccccac cgagcucucc gccaucucca     1200

ugcucuaccu cgacgaguac gacaaggucg uccucaagaa cuaccaggag auggucgucg     1260

agggcugcgg cugccgcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  2819
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt2)

<400>  2819
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gccucggccg ccgcgcccag uggcucugcu gguggugggg ccuccucugc uccugcugcg      120

gccccccccc ccuccgcccc ccccuccccg ccgccgccgc cgccgccgcc ggcggccagc      180

uccucggcga cggcggcucc cccggccgca ccgagcagcc cccccccucc ccccaguccu      240

ccuccggcuu ccucuaccgc cgccucaaga cccaggagaa gcgcgagaug cagaaggaga      300

uccucuccgu ccucggccuc ccccaccgcc cccgcccccu ccacggccuc cagcagcccc      360

agccccccgc ccuccgccag caggaggagc agcagcagca gcagcagcuc ccccgcggcg      420

agcccccccc cggccgccuc aaguccgccc cccucuucau gcucgaccuc uacaacgccc      480

ucuccgccga caacgacgag gacggcgccu ccgagggcga gcgccagcag uccuggcccc      540

acgaggccgc cuccuccucc cagcgccgcc agcccccccc cggcgccgcc cacccccuca      600

accgcaaguc ccuccucgcc cccggcuccg gcuccggcgg cgccuccccc cucaccuccg      660

cccaggacuc cgccuuccuc aacgacgccg acauggucau guccuucguc aaccucgucg      720

aguacgacaa ggaguucucc ccccgccagc gccaccacaa ggaguucaag uucaaccucu      780

cccagauccc cgagggcgag gucgucaccg ccgccgaguu ccgcaucuac aaggacugcg      840

ucaugggcuc cuucaagaac cagaccuucc ucaucuccau cuaccagguc cuccaggagc      900

accagcaccg cgacuccgac cucuuccucc ucgacacccg cgucgucugg gccuccgagg      960

agggcuggcu cgaguucgac aucaccgcca ccuccaaccu cugggucguc accccccagc     1020

acaacauggg ccuccagcuc uccgucguca cccgcgacgg cguccacguc cacccccgcg     1080

ccgccggccu cgucggccgc gacggccccu acgacaagca gcccuucaug gucgccuucu     1140

ucaaggucuc cgagguccac guccgcacca cccgcuccgc cuccucccgc cgccgccagc     1200

agucccgcaa ccgcuccacc cagucccagg acgucgcccg cgucuccucc gccuccgacu     1260

acaacuccuc cgagcucaag accgccugcc gcaagcacga gcucuacguc uccuuccagg     1320

accucggcug gcaggacugg aucaucgccc ccaagggcua cgccgccaac uacugcgacg     1380

gcgagugcuc cuucccccuc aacgcccaca ugaacgccac caaccacgcc aucguccaga     1440

cccucgucca ccucaugaac cccgaguacg uccccaagcc cugcugcgcc cccaccaagc     1500

ucaacgccau cuccguccuc uacuucgacg acaacuccaa cgucauccuc aagaaguacc     1560

gcaacauggu cguccgcgcc ugcggcugcc acugaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  2820
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt2)

<400>  2820
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

uccgcucccu ccgcgccgcc gccccccacu ccuucgucgc ccucugggcc ccccucuucc      120

uccuccgcuc cgcccucgcc gacuucuccc ucgacaacga gguccacucc uccuucaucc      180

accgccgccu ccgcucccag gagcgccgcg agaugcagcg cgagauccuc uccauccucg      240

gccuccccca ccgcccccgc ccccaccucc agggcaagca caacuccgcc cccauguuca      300

ugcucgaccu cuacaacgcc auggccgucg aggagggcgg cggccccggc ggccagggcu      360

ucuccuaccc cuacaaggcc gucuucucca cccagggccc cccccucgcc ucccuccagg      420

acucccacuu ccucaccgac gccgacaugg ucauguccuu cgucaaccuc gucgagcacg      480

acaaggaguu cuuccacccc cgcuaccacc accgcgaguu ccgcuucgac cucuccaaga      540

uccccgaggg cgaggccguc accgccgccg aguuccgcau cuacaaggac uacauccgcg      600

agcgcuucga caacgagacc uuccgcaucu ccgucuacca gguccuccag gagcaccucg      660

gccgcgaguc cgaccucuuc cuccucgacu cccgcacccu cugggccucc gaggagggcu      720

ggcucgucuu cgacaucacc gccaccucca accacugggu cgucaacccc cgccacaacc      780

ucggccucca gcucuccguc gagacccucg acggccaguc caucaacccc aagcucgccg      840

gccucaucgg ccgccacggc ccccagaaca agcagcccuu cauggucgcc uucuucaagg      900

ccaccgaggu ccacuuccgc uccauccgcu ccaccggcuc caagcagcgc ucccagaacc      960

gcuccaagac ccccaagaac caggaggccc uccgcauggc caacgucgcc gagaacuccu     1020

ccuccgacca gcgccaggcc ugcaagaagc acgagcucua cgucuccuuc cgcgaccucg     1080

gcuggcagga cuggaucauc gcccccgagg gcuacgccgc cuacuacugc gagggcgagu     1140

gcgccuuccc ccucaacucc uacaugaacg ccaccaacca cgccaucguc cagacccucg     1200

uccacuucau caaccccgag accgucccca agcccugcug cgcccccacc cagcucaacg     1260

ccaucuccgu ccucuacuuc gacgacuccu ccaacgucau ccucaagaag uaccgcaaca     1320

uggucguccg cgccugcggc ugccacugag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  2821
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt2)

<400>  2821
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagg       60

ccuccgccgc ccuccucugc cuccuccuca ccgccgccgc cuucuccccc cagggccucg      120

cccagcccgu cggcaucaac accuccacca ccugcugcua ccgcuucauc aacaagaaga      180

uccccaagca gcgccucgag uccuaccgcc gcaccaccuc cucccacugc ccccgcgagg      240

ccgucaucuu caagaccaag cucgacaagg agaucugcgc cgaccccacc cagaaguggg      300

uccaggacuu caugaagcac cucgacaaga agacccagac ccccaagcuc ugaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  2822
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt2)

<400>  2822
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcucc       60

ucacccucau cauccuccuc cccgucgucu ccaaguucuc cuucgucucc cucuccgccc      120

cccagcacug guccugcccc gagggcaccc ucgccggcaa cggcaacucc accugcgucg      180

gccccgcccc cuuccucauc uucucccacg gcaacuccau cuuccgcauc gacaccgagg      240

gcaccaacua cgagcagcuc gucgucgacg ccggcgucuc cgucaucaug gacuuccacu      300

acaacgagaa gcgcaucuac ugggucgacc ucgagcgcca gcuccuccag cgcgucuucc      360

ucaacggcuc ccgccaggag cgcgucugca acaucgagaa gaacgucucc ggcauggcca      420

ucaacuggau caacgaggag gucaucuggu ccaaccagca ggagggcauc aucaccguca      480

ccgacaugaa gggcaacaac ucccacaucc uccucuccgc ccucaaguac cccgccaacg      540

ucgccgucga ccccgucgag cgcuucaucu ucugguccuc cgaggucgcc ggcucccucu      600

accgcgccga ccucgacggc gucggcguca aggcccuccu cgagaccucc gagaagauca      660

ccgccgucuc ccucgacguc cucgacaagc gccucuucug gauccaguac aaccgcgagg      720

gcuccaacuc ccucaucugc uccugcgacu acgacggcgg cuccguccac aucuccaagc      780

accccaccca gcacaaccuc uucgccaugu cccucuucgg cgaccgcauc uucuacucca      840

ccuggaagau gaagaccauc uggaucgcca acaagcacac cggcaaggac augguccgca      900

ucaaccucca cuccuccuuc gucccccucg gcgagcucaa ggucguccac ccccucgccc      960

agcccaaggc cgaggacgac accugggagc ccgagcagaa gcucugcaag cuccgcaagg     1020

gcaacugcuc cuccaccguc ugcggccagg accuccaguc ccaccucugc augugcgccg     1080

agggcuacgc ccucucccgc gaccgcaagu acugcgagga cgucaacgag ugcgccuucu     1140

ggaaccacgg cugcacccuc ggcugcaaga acacccccgg cuccuacuac ugcaccugcc     1200

ccgucggcuu cguccuccuc cccgacggca agcgcugcca ccagcucguc uccugccccc     1260

gcaacgucuc cgagugcucc cacgacugcg uccucaccuc cgagggcccc cucugcuucu     1320

gccccgaggg cuccguccuc gagcgcgacg gcaagaccug cuccggcugc uccucccccg     1380

acaacggcgg cugcucccag cucugcgucc cccucucccc cgucuccugg gagugcgacu     1440

gcuuccccgg cuacgaccuc cagcucgacg agaaguccug cgccgccucc ggcccccagc     1500

ccuuccuccu cuucgccaac ucccaggaca uccgccacau gcacuucgac ggcaccgacu     1560

acggcacccu ccucucccag cagaugggca uggucuacgc ccucgaccac gaccccgucg     1620

agaacaagau cuacuucgcc cacaccgccc ucaaguggau cgagcgcgcc aacauggacg     1680

gcucccagcg cgagcgccuc aucgaggagg gcgucgacgu ccccgagggc cucgccgucg     1740

acuggaucgg ccgccgcuuc uacuggaccg accgcggcaa gucccucauc ggccgcuccg     1800

accucaacgg caagcgcucc aagaucauca ccaaggagaa caucucccag ccccgcggca     1860

ucgccgucca ccccauggcc aagcgccucu ucuggaccga caccggcauc aacccccgca     1920

ucgaguccuc cucccuccag ggccucggcc gccucgucau cgccuccucc gaccucaucu     1980

ggcccuccgg caucaccauc gacuuccuca ccgacaagcu cuacuggugc gacgccaagc     2040

aguccgucau cgagauggcc aaccucgacg gcuccaagcg ccgccgccuc acccagaacg     2100

acgucggcca ccccuucgcc gucgccgucu ucgaggacua cgucugguuc uccgacuggg     2160

ccaugcccuc cgucaugcgc gucaacaagc gcaccggcaa ggaccgcguc cgccuccagg     2220

gcuccaugcu caagcccucc ucccucgucg ucguccaccc ccucgccaag cccggcgccg     2280

accccugccu cuaccagaac ggcggcugcg agcacaucug caagaagcgc cucggcaccg     2340

ccuggugcuc cugccgcgag ggcuucauga aggccuccga cggcaagacc ugccucgccc     2400

ucgacggcca ccagcuccuc gccggcggcg aggucgaccu caagaaccag gucacccccc     2460

ucgacauccu cuccaagacc cgcgucuccg aggacaacau caccgagucc cagcacaugc     2520

ucgucgccga gaucaugguc uccgaccagg acgacugcgc ccccgucggc ugcuccaugu     2580

acgcccgcug caucuccgag ggcgaggacg ccaccugcca gugccucaag ggcuucgccg     2640

gcgacggcaa gcucugcucc gacaucgacg agugcgagau gggcgucccc gucugccccc     2700

ccgccuccuc caagugcauc aacaccgagg gcggcuacgu cugccgcugc uccgagggcu     2760

accagggcga cggcauccac ugccucgaca ucgacgagug ccagcucggc gagcacuccu     2820

gcggcgagaa cgccuccugc accaacaccg agggcggcua caccugcaug ugcgccggcc     2880

gccucuccga gcccggccuc aucugccccg acuccacccc ccccccccac cuccgcgagg     2940

acgaccacca cuacuccguc cgcaacuccg acuccgagug cccccucucc cacgacggcu     3000

acugccucca cgacggcguc ugcauguaca ucgaggcccu cgacaaguac gccugcaacu     3060

gcgucgucgg cuacaucggc gagcgcugcc aguaccgcga ccucaagugg ugggagcucc     3120

gccacgccgg ccacggccag cagcagaagg ucaucgucgu cgccgucugc gucgucgucc     3180

ucgucaugcu ccuccuccuc ucccucuggg gcgcccacua cuaccgcacc cagaagcucc     3240

ucuccaagaa ccccaagaac cccuacgagg aguccucccg cgacguccgc ucccgccgcc     3300

ccgccgacac cgaggacggc auguccuccu gcccccagcc cugguucguc gucaucaagg     3360

agcaccagga ccucaagaac ggcggccagc ccgucgccgg cgaggacggc caggccgccg     3420

acggcuccau gcagcccacc uccuggcgcc aggagcccca gcucugcggc augggcaccg     3480

agcagggcug cuggaucccc gucuccuccg acaagggcuc cugcccccag gucauggagc     3540

gcuccuucca caugcccucc uacggcaccc agacccucga gggcggcguc gagaagcccc     3600

acucccuccu cuccgccaac ccccucuggc agcagcgcgc ccucgacccc ccccaccaga     3660

uggagcucac ccagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  2823
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt2)

<400>  2823
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

ccggccgccg cauggagaug cucugcgccg gccgcguccc cgcccuccuc cucugccucg      120

gcuuccaccu ccuccaggcc guccucucca ccaccgucau ccccuccugc auccccggcg      180

aguccuccga caacugcacc gcccucgucc agaccgagga caacccccgc gucgcccagg      240

ucuccaucac caagugcucc uccgacauga acggcuacug ccuccacggc cagugcaucu      300

accucgucga caugucccag aacuacugcc gcugcgaggu cggcuacacc ggcguccgcu      360

gcgagcacuu cuuccucacc guccaccagc cccucuccaa ggaguacguc gcccucaccg      420

ucauccucau cauccucuuc cucaucaccg ucgucggcuc caccuacuac uucugccgcu      480

gguaccgcaa ccgcaagucc aaggagccca agaaggagua cgagcgcguc accuccggcg      540

accccgagcu cccccagguc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  2824
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt2)

<400>  2824
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

agggcgagau caccaccuuc accgcccuca ccgagaaguu caaccucccc cccggcaacu      120

acaagaagcc caagcuccuc uacugcucca acggcggcca cuuccuccgc auccuccccg      180

acggcaccgu cgacggcacc cgcgaccgcu ccgaccagca cauccagcuc cagcucuccg      240

ccgaguccgu cggcgagguc uacaucaagu ccaccgagac cggccaguac cucgccaugg      300

acaccgacgg ccuccucuac ggcucccaga cccccaacga ggagugccuc uuccucgagc      360

gccucgagga gaaccacuac aacaccuaca ucuccaagaa gcacgccgag aagaacuggu      420

ucgucggccu caagaagaac ggcuccugca agcgcggccc ccgcacccac uacggccaga      480

aggccauccu cuuccucccc cuccccgucu ccuccgacug aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  2825
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt2)

<400>  2825
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucg       60

gcgucggcgg cggcgacguc gaggacguca ccccccgccc cggcggcugc cagaucuccg      120

gccgcggcgc ccgcggcugc aacggcaucc ccggcgccgc cgccugggag gccgcccucc      180

cccgccgccg cccccgccgc caccccuccg ucaacccccg cucccgcgcc gccggcuccc      240

cccgcacccg cggccgccgc accgaggagc gccccuccgg cucccgccuc ggcgaccgcg      300

gccgcggccg cgcccucccc ggcggccgcc ucggcggccg cggccgcggc cgcgcccccg      360

agcgcgucgg cggccgcggc cgcggccgcg gcaccgccgc cccccgcgcc gcccccgccg      420

cccgcggcuc ccgccccggc cccgccggca ccauggccgc cggcuccauc accacccucc      480

ccgcccuccc cgaggacggc ggcuccggcg ccuucccccc cggccacuuc aaggacccca      540

agcgccucua cugcaagaac ggcggcuucu uccuccgcau ccaccccgac ggccgcgucg      600

acggcguccg cgagaagucc gacccccaca ucaagcucca gcuccaggcc gaggagcgcg      660

gcgucgucuc caucaagggc gucugcgcca accgcuaccu cgccaugaag gaggacggcc      720

gccuccucgc cuccaagugc gucaccgacg agugcuucuu cuucgagcgc cucgagucca      780

acaacuacaa caccuaccgc ucccgcaagu acaccuccug guacgucgcc cucaagcgca      840

ccggccagua caagcucggc uccaagaccg gccccggcca gaaggccauc cucuuccucc      900

ccauguccgc caaguccuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  2826
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt2)

<400>  2826
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aguggauccu caccuggauc cuccccaccc uccucuaccg cuccugcuuc cacaucaucu      120

gccucgucgg caccaucucc cucgccugca acgacaugac ccccgagcag auggccacca      180

acgucaacug cuccuccccc gagcgccaca cccgcuccua cgacuacaug gagggcggcg      240

acauccgcgu ccgccgccuc uucugccgca cccaguggua ccuccgcauc gacaagcgcg      300

gcaaggucaa gggcacccag gagaugaaga acaacuacaa caucauggag auccgcaccg      360

ucgccgucgg caucgucgcc aucaagggcg ucgaguccga guucuaccuc gccaugaaca      420

aggagggcaa gcucuacgcc aagaaggagu gcaacgagga cugcaacuuc aaggagcuca      480

uccucgagaa ccacuacaac accuacgccu ccgccaagug gacccacaac ggcggcgaga      540

uguucgucgc ccucaaccag aagggcaucc ccguccgcgg caagaagacc aagaaggagc      600

agaagaccgc ccacuuccuc cccauggcca ucaccugagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  2827
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt2)

<400>  2827
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

uccuccccuc cgucguccuc aagcucuucc ucgccgccgu ccucuccgcc cucgucaccg      120

gcgagucccu cgagcgccuc cgccgcggcc ucgccgccgg caccuccaac cccgaccccc      180

ccaccgucuc caccgaccag cuccuccccc ucggcggcgg ccgcgaccgc aagguccgcg      240

accuccagga ggccgaccuc gaccuccucc gcgucacccu cuccuccaag ccccaggccc      300

ucgccacccc caacaaggag gagcacggca agcgcaagaa gaagggcaag ggccucggca      360

agaagcgcga ccccugccuc cgcaaguaca aggacuucug cauccacggc gagugcaagu      420

acgucaagga gcuccgcgcc cccuccugca ucugccaccc cggcuaccac ggcgagcgcu      480

gccacggccu cucccucccc gucgagaacc gccucuacac cuacgaccac accaccaucc      540

ucgccgucgu cgccgucguc cucuccuccg ucugccuccu cgucaucguc ggccuccuca      600

uguuccgcua ccaccgccgc ggcggcuacg acgucgagaa cgaggagaag gucaagcucg      660

gcaugaccaa cucccacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  2828
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt2)

<400>  2828
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ucaccaagcu ccuccccgcc cuccuccucc agcacguccu ccuccaccuc cuccuccucc      120

ccaucgccau ccccuacgcc gagggccagc gcaagcgccg caacaccauc cacgaguuca      180

agaaguccgc caagaccacc cucaucaaga ucgaccccgc ccucaagauc aagaccaaga      240

aggucaacac cgccgaccag ugcgccaacc gcugcacccg caacaagggc cuccccuuca      300

ccugcaaggc cuucgucuuc gacaaggccc gcaagcagug ccucugguuc cccuucaacu      360

ccauguccuc cggcgucaag aaggaguucg gccacgaguu cgaccucuac gagaacaagg      420

acuacauccg caacugcauc aucggcaagg gccgcuccua caagggcacc gucuccauca      480

ccaaguccgg caucaagugc cagcccuggu ccuccaugau cccccacgag cacuccuucc      540

uccccuccuc cuaccgcggc aaggaccucc aggagaacua cugccgcaac ccccgcggcg      600

aggagggcgg ccccuggugc uucaccucca accccgaggu ccgcuacgag gucugcgaca      660

ucccccagug cuccgagguc gagugcauga ccugcaacgg cgaguccuac cgcggccuca      720

uggaccacac cgaguccggc aagaucugcc agcgcuggga ccaccagacc ccccaccgcc      780

acaaguuccu ccccgagcgc uaccccgaca agggcuucga cgacaacuac ugccgcaacc      840

ccgacggcca gccccgcccc uggugcuaca cccucgaccc ccacacccgc ugggaguacu      900

gcgccaucaa gaccugcgcc gacaacacca ugaacgacac cgacgucccc cucgagacca      960

ccgagugcau ccagggccag ggcgagggcu accgcggcac cgucaacacc aucuggaacg     1020

gcauccccug ccagcgcugg gacucccagu acccccacga gcacgacaug acccccgaga     1080

acuucaagug caaggaccuc cgcgagaacu acugccgcaa ccccgacggc uccgaguccc     1140

ccuggugcuu caccaccgac cccaacaucc gcgucggcua cugcucccag auccccaacu     1200

gcgacauguc ccacggccag gacugcuacc gcggcaacgg caagaacuac augggcaacc     1260

ucucccagac ccgcuccggc cucaccugcu ccauguggga caagaacaug gaggaccucc     1320

accgccacau cuucugggag cccgacgccu ccaagcucaa cgagaacuac ugccgcaacc     1380

ccgacgacga cgcccacggc cccuggugcu acaccggcaa cccccucauc cccugggacu     1440

acugccccau cucccgcugc gagggcgaca ccacccccac caucgucaac cucgaccacc     1500

ccgucaucuc cugcgccaag accaagcagc uccgcgucgu caacggcauc cccacccgca     1560

ccaacaucgg cuggaugguc ucccuccgcu accgcaacaa gcacaucugc ggcggcuccc     1620

ucaucaagga guccuggguc cucaccgccc gccagugcuu ccccucccgc gaccucaagg     1680

acuacgaggc cuggcucggc auccacgacg uccacggccg cggcgacgag aagugcaagc     1740

agguccucaa cgucucccag cucgucuacg gccccgaggg cuccgaccuc guccucauga     1800

agcucgcccg ccccgccguc cucgacgacu ucgucuccac caucgaccuc cccaacuacg     1860

gcugcaccau ccccgagaag accuccugcu ccgucuacgg cuggggcuac accggccuca     1920

ucaacuacga cggccuccuc cgcgucgccc accucuacau caugggcaac gagaagugcu     1980

cccagcacca ccgcggcaag gucacccuca acgaguccga gaucugcgcc ggcgccgaga     2040

agaucggcuc cggccccugc gagggcgacu acggcggccc ccucgucugc gagcagcaca     2100

agaugcgcau gguccucggc gucaucgucc ccggccgcgg cugcgccauc cccaaccgcc     2160

ccggcaucuu cguccgcguc gccuacuacg ccaaguggau ccacaagauc auccucaccu     2220

acaagguccc ccaguccuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  2829
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt2)

<400>  2829
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aggccgccgc caucggcauc gaccucggca ccaccuacuc cugcgucggc gucuuccagc      120

acggcaaggu cgagaucauc gccaacgacc agggcaaccg caccaccccc uccuacgucg      180

ccuucaccga caccgagcgc cucaucggcg acgccgccaa gaaccagguc gcccucaacc      240

cccagaacac cgucuucgac gccaagcgcc ucaucggccg caaguucggc gaccccgucg      300

uccaguccga caugaagcac uggcccuucc aggucaucaa cgacggcgac aagcccaagg      360

uccaggucuc cuacaagggc gagaccaagg ccuucuaccc cgaggagauc uccuccaugg      420

uccucaccaa gaugaaggag aucgccgagg ccuaccucgg cuaccccguc accaacgccg      480

ucaucaccgu ccccgccuac uucaacgacu cccagcgcca ggccaccaag gacgccggcg      540

ucaucgccgg ccucaacguc cuccgcauca ucaacgagcc caccgccgcc gccaucgccu      600

acggccucga ccgcaccggc aagggcgagc gcaacguccu caucuucgac cucggcggcg      660

gcaccuucga cgucuccauc cucaccaucg acgacggcau cuucgagguc aaggccaccg      720

ccggcgacac ccaccucggc ggcgaggacu ucgacaaccg ccucgucaac cacuucgucg      780

aggaguucaa gcgcaagcac aagaaggaca ucucccagaa caagcgcgcc guccgccgcc      840

uccgcaccgc cugcgagcgc gccaagcgca cccucuccuc cuccacccag gccucccucg      900

agaucgacuc ccucuucgag ggcaucgacu ucuacaccuc caucacccgc gcccgcuucg      960

aggagcucug cuccgaccuc uuccgcucca cccucgagcc cgucgagaag gcccuccgcg     1020

acgccaagcu cgacaaggcc cagauccacg accucguccu cgucggcggc uccacccgca     1080

uccccaaggu ccagaagcuc cuccaggacu ucuucaacgg ccgcgaccuc aacaagucca     1140

ucaaccccga cgaggccguc gccuacggcg ccgccgucca ggccgccauc cucaugggcg     1200

acaaguccga gaacguccag gaccuccucc uccucgacgu cgccccccuc ucccucggcc     1260

ucgagaccgc cggcggcguc augaccgccc ucaucaagcg caacuccacc auccccacca     1320

agcagaccca gaucuucacc accuacuccg acaaccagcc cggcguccuc auccaggucu     1380

acgagggcga gcgcgccaug accaaggaca acaaccuccu cggccgcuuc gagcucuccg     1440

gcaucccccc cgccccccgc ggcguccccc agaucgaggu caccuucgac aucgacgcca     1500

acggcauccu caacgucacc gccaccgaca aguccaccgg caaggccaac aagaucacca     1560

ucaccaacga caagggccgc cucuccaagg aggagaucga gcgcaugguc caggaggccg     1620

agaaguacaa ggccgaggac gagguccagc gcgagcgcgu cuccgccaag aacgcccucg     1680

aguccuacgc cuucaacaug aaguccgccg ucgaggacga gggccucaag ggcaagaucu     1740

ccgaggccga caagaagaag guccucgaca agugccagga ggucaucucc uggcucgacg     1800

ccaacacccu cgccgagaag gacgaguucg agcacaagcg caaggagcuc gagcaggucu     1860

gcaaccccau caucuccggc cucuaccagg gcgccggcgg ccccggcccc ggcggcuucg     1920

gcgcccaggg ccccaagggc ggcuccggcu ccggccccac caucgaggag gucgacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  2830
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt2)

<400>  2830
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aggccgccgc caucggcauc gaccucggca ccaccuacuc cugcgucggc gucuuccagc      120

acggcaaggu cgagaucauc gccaacgacc agggcaaccg caccaccccc uccuacgucg      180

ccuucaccga caccgagcgc cucaucggcg acgccgccaa gaaccagguc gcccucaacc      240

cccagaacac cgucuucgac gccaagcgcc ucaucggccg caaguucggc gaccccgucg      300

uccaguccga caugaagcac uggcccuucc aggucaucaa cgacggcgac aagcccaagg      360

uccaggucuc cuacaagggc gagaccaagg ccuucuaccc cgaggagauc uccuccaugg      420

uccucaccaa gaugaaggag aucgccgagg ccuaccucgg cuaccccguc accaacgccg      480

ucaucaccgu ccccgccuac uucaacgacu cccagcgcca ggccaccaag gacgccggcg      540

ucaucgccgg ccucaacguc cuccgcauca ucaacgagcc caccgccgcc gccaucgccu      600

acggccucga ccgcaccggc aagggcgagc gcaacguccu caucuucgac cucggcggcg      660

gcaccuucga cgucuccauc cucaccaucg acgacggcau cuucgagguc aaggccaccg      720

ccggcgacac ccaccucggc ggcgaggacu ucgacaaccg ccucgucaac cacuucgucg      780

aggaguucaa gcgcaagcac aagaaggaca ucucccagaa caagcgcgcc guccgccgcc      840

uccgcaccgc cugcgagcgc gccaagcgca cccucuccuc cuccacccag gccucccucg      900

agaucgacuc ccucuucgag ggcaucgacu ucuacaccuc caucacccgc gcccgcuucg      960

aggagcucug cuccgaccuc uuccgcucca cccucgagcc cgucgagaag gcccuccgcg     1020

acgccaagcu cgacaaggcc cagauccacg accucguccu cgucggcggc uccacccgca     1080

uccccaaggu ccagaagcuc cuccaggacu ucuucaacgg ccgcgaccuc aacaagucca     1140

ucaaccccga cgaggccguc gccuacggcg ccgccgucca ggccgccauc cucaugggcg     1200

acaaguccga gaacguccag gaccuccucc uccucgacgu cgccccccuc ucccucggcc     1260

ucgagaccgc cggcggcguc augaccgccc ucaucaagcg caacuccacc auccccacca     1320

agcagaccca gaucuucacc accuacuccg acaaccagcc cggcguccuc auccaggucu     1380

acgagggcga gcgcgccaug accaaggaca acaaccuccu cggccgcuuc gagcucuccg     1440

gcaucccccc cgccccccgc ggcguccccc agaucgaggu caccuucgac aucgacgcca     1500

acggcauccu caacgucacc gccaccgaca aguccaccgg caaggccaac aagaucacca     1560

ucaccaacga caagggccgc cucuccaagg aggagaucga gcgcaugguc caggaggccg     1620

agaaguacaa ggccgaggac gagguccagc gcgagcgcgu cuccgccaag aacgcccucg     1680

aguccuacgc cuucaacaug aaguccgccg ucgaggacga gggccucaag ggcaagaucu     1740

ccgaggccga caagaagaag guccucgaca agugccagga ggucaucucc uggcucgacg     1800

ccaacacccu cgccgagaag gacgaguucg agcacaagcg caaggagcuc gagcaggucu     1860

gcaaccccau caucuccggc cucuaccagg gcgccggcgg ccccggcccc ggcggcuucg     1920

gcgcccaggg ccccaagggc ggcuccggcu ccggccccac caucgaggag gucgacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  2831
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt2)

<400>  2831
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

ccgccaaggg caucgccauc ggcaucgacc ucggcaccac cuacuccugc gucggcgucu      120

uccagcacgg caaggucgag aucaucgcca acgaccaggg caaccgcacc acccccuccu      180

acgucgccuu caccgacacc gagcgccuca ucggcgacgc cgccaagaac caggucgcca      240

ugaaccccca gaacaccguc uucgacgcca agcgccucau cggccgcaag uucaacgacc      300

ccgucgucca ggccgacaug aagcucuggc ccuuccaggu caucaacgag ggcggcaagc      360

ccaagguccu cgucuccuac aagggcgaga acaaggccuu cuaccccgag gagaucuccu      420

ccaugguccu caccaagcuc aaggagaccg ccgaggccuu ccucggccac cccgucacca      480

acgccgucau caccgucccc gccuacuuca acgacuccca gcgccaggcc accaaggacg      540

ccggcgucau cgccggccuc aacguccucc gcaucaucaa cgagcccacc gccgccgcca      600

ucgccuacgg ccucgacaag ggcggccagg gcgagcgcca cguccucauc uucgaccucg      660

gcggcggcac cuucgacguc uccauccuca ccaucgacga cggcaucuuc gaggucaagg      720

ccaccgccgg cgacacccac cucggcggcg aggacuucga caaccgccuc gucucccacu      780

ucgucgagga guucaagcgc aagcacaaga aggacaucuc ccagaacaag cgcgccgucc      840

gccgccuccg caccgccugc gagcgcgcca agcgcacccu cuccuccucc acccaggcca      900

accucgagau cgacucccuc uacgagggca ucgacuucua caccuccauc acccgcgccc      960

gcuucgagga gcucugcgcc gaccucuucc gcggcacccu cgagcccguc gagaaggccc     1020

uccgcgacgc caagauggac aaggccaaga uccacgacau cguccucguc ggcggcucca     1080

cccgcauccc caagguccag cgccuccucc aggacuacuu caacggccgc gaccucaaca     1140

aguccaucaa ccccgacgag gccgucgccu acggcgccgc cguccaggcc gccauccuca     1200

ugggcgacaa guccgagaag guccaggacc uccuccuccu cgacgucgcc ccccucuccc     1260

ucggccucga gaccgccggc ggcgucauga ccgcccucau caagcgcaac uccaccaucc     1320

ccaccaagca gacccagauc uucaccaccu acuccgacaa ccagcccggc guccucaucc     1380

aggucuacga gggcgagcgc gccaugacca aggacaacaa ccuccucggc cgcuucgacc     1440

ucaccggcau cccccccgcc ccccgcggcg ucccccagau cgaggucacc uucgacaucg     1500

acgccaacgg cauccucaac gucaccgcca ccgacaaguc caccggcaag gucaacaaga     1560

ucaccaucac caacgacaag ggccgccucu ccaaggagga gaucgagcgc augguccucg     1620

acgccgagaa guacaaggcc gaggacgagg uccagcgcga gaagaucgcc gccaagaacg     1680

cccucgaguc cuacgccuuc aacaugaagu ccgucgucuc cgacgagggc cucaagggca     1740

agaucuccga guccgacaag aacaagaucc ucgacaagug caacgagcuc cucuccuggc     1800

ucgaggucaa ccagcucgcc gagaaggacg aguucgacca caagcgcaag gagcucgagc     1860

agaugugcaa ccccaucauc accaagcucu accagggcgg cugcaccggc cccgccugcg     1920

gcaccggcua cguccccggc cgccccgcca ccggccccac caucgaggag gucgacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  2832
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt2)

<400>  2832
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccg       60

cccgcggccc cgccaucggc aucgaccucg gcaccaccua cuccugcguc ggcgucuucc      120

agcacggcaa ggucgagauc aucgccaacg accagggcaa ccgcaccacc cccuccuacg      180

ucgccuucac cgacaccgag cgccucaucg gcgacgccgc caagaaccag gucgccauga      240

accccaccaa caccaucuuc gacgccaagc gccucaucgg ccgcaaguuc gaggacgcca      300

ccguccaguc cgacaugaag cacuggcccu uccgcgucgu cuccgagggc ggcaagccca      360

agguccaggu cgaguacaag ggcgagacca agaccuucuu ccccgaggag aucuccucca      420

ugguccucac caagaugaag gagaucgccg aggccuaccu cggcggcaag guccacuccg      480

ccgucaucac cguccccgcc uacuucaacg acucccagcg ccaggccacc aaggacgccg      540

gcaccaucac cggccucaac guccuccgca ucaucaacga gcccaccgcc gccgccaucg      600

ccuacggccu cgacaagaag ggcugcgccg gcggcgagaa gaacguccuc aucuucgacc      660

ucggcggcgg caccuucgac gucuccaucc ucaccaucga ggacggcauc uucgagguca      720

aguccaccgc cggcgacacc caccucggcg gcgaggacuu cgacaaccgc auggucuccc      780

accucgccga ggaguucaag cgcaagcaca agaaggacau cggccccaac aagcgcgccg      840

uccgccgccu ccgcaccgcc ugcgagcgcg ccaagcgcac ccucuccucc uccacccagg      900

ccuccaucga gaucgacucc cucuacgagg gcgucgacuu cuacaccucc aucacccgcg      960

cccgcuucga ggagcucaac gccgaccucu uccgcggcac ccucgagccc gucgagaagg     1020

cccuccgcga cgccaagcuc gacaagggcc agauccagga gaucguccuc gucggcggcu     1080

ccacccgcau ccccaagauc cagaagcucc uccaggacuu cuucaacggc aaggagcuca     1140

acaaguccau caaccccgac gaggccgucg ccuacggcgc cgccguccag gccgccaucc     1200

ucaucggcga caaguccgag aacguccagg accuccuccu ccucgacguc accccccucu     1260

cccucggcau cgagaccgcc ggcggcguca ugaccccccu caucaagcgc aacaccacca     1320

uccccaccaa gcagacccag accuucacca ccuacuccga caaccagucc uccguccucg     1380

uccaggucua cgagggcgag cgcgccauga ccaaggacaa caaccuccuc ggcaaguucg     1440

accucaccgg cauccccccc gccccccgcg gcguccccca gaucgagguc accuucgaca     1500

ucgacgccaa cggcauccuc aacgucaccg ccgccgacaa guccaccggc aaggagaaca     1560

agaucaccau caccaacgac aagggccgcc ucuccaagga cgacaucgac cgcauggucc     1620

aggaggccga gcgcuacaag uccgaggacg aggccaaccg cgaccgcguc gccgccaaga     1680

acgcccucga guccuacacc uacaacauca agcagaccgu cgaggacgag aagcuccgcg     1740

gcaagaucuc cgagcaggac aagaacaaga uccucgacaa gugccaggag gucaucaacu     1800

ggcucgaccg caaccagaug gccgagaagg acgaguacga gcacaagcag aaggagcucg     1860

agcgcgucug caaccccauc aucuccaagc ucuaccaggg cggccccggc ggcggcuccg     1920

gcggcggcgg cuccggcgcc uccggcggcc ccaccaucga ggaggucgac ugaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  2833
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt2)

<400>  2833
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccg       60

ucgucggcau cgaccucggc uuccaguccu gcuacgucgc cgucgcccgc gccggcggca      120

ucgagaccau cgccaacgag uacuccgacc gcugcacccc cgccugcauc uccuucggcc      180

ccaagaaccg cuccaucggc gccgccgcca agucccaggu caucuccaac gccaagaaca      240

ccguccaggg cuucaagcgc uuccacggcc gcgccuucuc cgaccccuuc gucgaggccg      300

agaaguccaa ccucgccuac gacaucgucc agcuccccac cggccucacc ggcaucaagg      360

ucaccuacau ggaggaggag cgcaacuuca ccaccgagca ggucaccgcc augcuccucu      420

ccaagcucaa ggagaccgcc gaguccgucc ucaagaagcc cgucgucgac ugcgucgucu      480

ccguccccug cuucuacacc gacgccgagc gccgcuccgu cauggacgcc acccagaucg      540

ccggccucaa cugccuccgc cucaugaacg agaccaccgc cgucgcccuc gccuacggca      600

ucuacaagca ggaccucccc gcccucgagg agaagccccg caacgucguc uucgucgaca      660

ugggccacuc cgccuaccag gucuccgucu gcgccuucaa ccgcggcaag cucaaggucc      720

ucgccaccgc cuucgacacc acccucggcg gccgcaaguu cgacgagguc cucgucaacc      780

acuucugcga ggaguucggc aagaaguaca agcucgacau caaguccaag auccgcgccc      840

uccuccgccu cucccaggag ugcgagaagc ucaagaagcu cauguccgcc aacgccuccg      900

accucccccu cuccaucgag ugcuucauga acgacgucga cgucuccggc accaugaacc      960

gcggcaaguu ccucgagaug ugcaacgacc uccucgcccg cgucgagccc ccccuccgcu     1020

ccguccucga gcagaccaag cucaagaagg aggacaucua cgccgucgag aucgucggcg     1080

gcgccacccg cauccccgcc gucaaggaga agaucuccaa guucuucggc aaggagcucu     1140

ccaccacccu caacgccgac gaggccguca cccgcggcug cgcccuccag ugcgccaucc     1200

ucucccccgc cuucaagguc cgcgaguucu ccaucaccga cgucgucccc uaccccaucu     1260

cccuccgcug gaacuccccc gccgaggagg gcuccuccga cugcgagguc uucuccaaga     1320

accacgccgc ccccuucucc aagguccuca ccuucuaccg caaggagccc uucacccucg     1380

aggccuacua cuccuccccc caggaccucc ccuaccccga ccccgccauc gcccaguucu     1440

ccguccagaa ggucaccccc caguccgacg gcuccuccuc caaggucaag gucaaggucc     1500

gcgucaacgu ccacggcauc uucuccgucu ccuccgccuc ccucgucgag guccacaagu     1560

ccgaggagaa cgaggagccc auggagaccg accagaacgc caaggaggag gagaagaugc     1620

aggucgacca ggaggagccc cacgucgagg agcagcagca gcagaccccc gccgagaaca     1680

aggccgaguc cgaggagaug gagaccuccc aggccggcuc caaggacaag aagauggacc     1740

agccccccca ggccaagaag gccaagguca agaccuccac cgucgaccuc cccaucgaga     1800

accagcuccu cuggcagauc gaccgcgaga ugcucaaccu cuacaucgag aacgagggca     1860

agaugaucau gcaggacaag cucgagaagg agcgcaacga cgccaagaac gccgucgagg     1920

aguacgucua cgagaugcgc gacaagcucu ccggcgagua cgagaaguuc gucuccgagg     1980

acgaccgcaa cuccuucacc cucaagcucg aggacaccga gaacuggcuc uacgaggacg     2040

gcgaggacca gcccaagcag gucuacgucg acaagcucgc cgagcucaag aaccucggcc     2100

agcccaucaa gauccgcuuc caggaguccg aggagcgccc caagcucuuc gaggagcucg     2160

gcaagcagau ccagcaguac augaagauca ucuccuccuu caagaacaag gaggaccagu     2220

acgaccaccu cgacgccgcc gacaugacca aggucgagaa guccaccaac gaggccaugg     2280

aguggaugaa caacaagcuc aaccuccaga acaagcaguc ccucaccaug gaccccgucg     2340

ucaaguccaa ggagaucgag gccaagauca aggagcucac cuccaccugc ucccccauca     2400

ucuccaagcc caagcccaag gucgagcccc ccaaggagga gcagaagaac gccgagcaga     2460

acggccccgu cgacggccag ggcgacaacc ccggccccca ggccgccgag cagggcaccg     2520

acaccgccgu ccccuccgac uccgacaaga agcuccccga gauggacauc gacugaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  2834
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt2)

<400>  2834
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccg       60

ucgucggcau cgaccucggc uuccucaacu gcuacaucgc cgucgcccgc uccggcggca      120

ucgagaccau cgccaacgag uacuccgacc gcugcacccc cgccugcauc ucccucggcu      180

cccgcacccg cgccaucggc aacgccgcca agucccagau cgucaccaac guccgcaaca      240

ccauccacgg cuucaagaag cuccacggcc gcuccuucga cgaccccauc guccagaccg      300

agcgcauccg ccuccccuac gagcuccaga agaugcccaa cggcuccgcc ggcgucaagg      360

uccgcuaccu cgaggaggag cgccccuucg ccaucgagca ggucaccggc augcuccucg      420

ccaagcucaa ggagaccucc gagaacgccc ucaagaagcc cgucgccgac ugcgucaucu      480

ccauccccuc cuucuucacc gacgccgagc gccgcuccgu cauggccgcc gcccaggucg      540

ccggccucaa cugccuccgc cucaugaacg agaccaccgc cgucgcccuc gccuacggca      600

ucuacaagca ggaccucccc ccccucgacg agaagccccg caacgucguc uucaucgaca      660

ugggccacuc cgccuaccag guccucgucu gcgccuucaa caagggcaag cucaaggucc      720

ucgccaccac cuucgacccc uaccucggcg gccgcaacuu cgacgaggcc cucgucgacu      780

acuucugcga cgaguucaag accaaguaca agaucaacgu caaggagaac ucccgcgccc      840

uccuccgccu cuaccaggag ugcgagaagc ucaagaagcu cauguccgcc aacgccuccg      900

accucccccu caacaucgag ugcuucauga acgaccucga cgucuccucc aagaugaacc      960

gcgcccaguu cgagcagcuc ugcgccuccc uccucgcccg cgucgagccc ccccucaagg     1020

ccgucaugga gcaggccaac cuccagcgcg aggacaucuc cuccaucgag aucgucggcg     1080

gcgccacccg cauccccgcc gucaaggagc agaucaccaa guucuuccuc aaggacaucu     1140

ccaccacccu caacgccgac gaggccgucg cccgcggcug cgcccuccag ugcgccaucc     1200

ucucccccgc cuucaagguc cgcgaguucu ccaucaccga ccucgucccc uacuccauca     1260

cccuccgcug gaagaccucc uucgaggacg gcuccggcga gugcgagguc uucugcaaga     1320

accaccccgc ccccuucucc aaggucauca ccuuccacaa gaaggagccc uucgagcucg     1380

aggccuucua caccaaccuc cacgaggucc ccuaccccga cgcccgcauc ggcuccuuca     1440

ccauccagaa cgucuucccc caguccgacg gcgacuccuc caaggucaag gucaaggucc     1500

gcgucaacau ccacggcauc uucuccgucg ccuccgccuc cgucaucgag aagcagaacc     1560

ucgagggcga ccacuccgac gcccccaugg agaccgagac cuccuucaag aacgagaaca     1620

aggacaacau ggacaagaug caggucgacc aggaggaggg ccaccagaag ugccacgccg     1680

agcacacccc cgaggaggag aucgaccaca ccggcgccaa gaccaagucc gccgucuccg     1740

acaagcagga ccgccucaac cagacccuca agaagggcaa ggucaagucc aucgaccucc     1800

ccauccaguc cucccucugc cgccagcucg gccaggaccu ccucaacucc uacaucgaga     1860

acgagggcaa gaugaucaug caggacaagc ucgagaagga gcgcaacgac gccaagaacg     1920

ccgucgagga guacgucuac gacuuccgcg accgccucgg caccgucuac gagaaguuca     1980

ucacccccga ggaccucucc aagcucuccg ccguccucga ggacaccgag aacuggcucu     2040

acgaggacgg cgaggaccag cccaagcagg ucuacgucga caagcuccag gagcucaaga     2100

aguacggcca gcccauccag augaaguaca uggagcacga ggagcgcccc aaggcccuca     2160

acgaccucgg caagaagauc cagcucguca ugaaggucau cgaggccuac cgcaacaagg     2220

acgagcgcua cgaccaccuc gaccccaccg agauggagaa ggucgagaag ugcaucuccg     2280

acgccauguc cuggcucaac uccaagauga acgcccagaa caagcucucc cucacccagg     2340

accccgucgu caaggucucc gagaucgucg ccaaguccaa ggagcucgac aacuucugca     2400

accccaucau cuacaagccc aagcccaagg ccgagguccc cgaggacaag cccaaggcca     2460

acuccgagca caacggcccc auggacggcc aguccggcac cgagaccaag uccgacucca     2520

ccaaggacuc cucccagcac accaaguccu ccggcgagau ggaggucgac ugaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  2835
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt2)

<400>  2835
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ucucccucgu cgccgccaug cuccuccucc ucuccgccgc ccgcgccgag gaggaggaca      120

agaaggagga cgucggcacc gucgucggca ucgaccucgg caccaccuac uccugcgucg      180

gcgucuucaa gaacggccgc gucgagauca ucgccaacga ccagggcaac cgcaucaccc      240

ccuccuacgu cgccuucacc cccgagggcg agcgccucau cggcgacgcc gccaagaacc      300

agcucaccuc caaccccgag aacaccgucu ucgacgccaa gcgccucauc ggccgcaccu      360

ggaacgaccc cuccguccag caggacauca aguuccuccc cuucaagguc gucgagaaga      420

agaccaagcc cuacauccag gucgacaucg gcggcggcca gaccaagacc uucgcccccg      480

aggagaucuc cgccaugguc cucaccaaga ugaaggagac cgccgaggcc uaccucggca      540

agaaggucac ccacgccguc gucaccgucc ccgccuacuu caacgacgcc cagcgccagg      600

ccaccaagga cgccggcacc aucgccggcc ucaacgucau gcgcaucauc aacgagccca      660

ccgccgccgc caucgccuac ggccucgaca agcgcgaggg cgagaagaac auccucgucu      720

ucgaccucgg cggcggcacc uucgacgucu cccuccucac caucgacaac ggcgucuucg      780

aggucgucgc caccaacggc gacacccacc ucggcggcga ggacuucgac cagcgcguca      840

uggagcacuu caucaagcuc uacaagaaga agaccggcaa ggacguccgc aaggacaacc      900

gcgccgucca gaagcuccgc cgcgaggucg agaaggccaa gcgcgcccuc uccucccagc      960

accaggcccg caucgagauc gaguccuucu acgagggcga ggacuucucc gagacccuca     1020

cccgcgccaa guucgaggag cucaacaugg accucuuccg cuccaccaug aagcccgucc     1080

agaagguccu cgaggacucc gaccucaaga aguccgacau cgacgagauc guccucgucg     1140

gcggcuccac ccgcaucccc aagauccagc agcucgucaa ggaguucuuc aacggcaagg     1200

agcccucccg cggcaucaac cccgacgagg ccgucgccua cggcgccgcc guccaggccg     1260

gcguccucuc cggcgaccag gacaccggcg accucguccu ccucgacguc ugcccccuca     1320

cccucggcau cgagaccguc ggcggcguca ugaccaagcu caucccccgc aacaccgucg     1380

uccccaccaa gaagucccag aucuucucca ccgccuccga caaccagccc accgucacca     1440

ucaaggucua cgagggcgag cgcccccuca ccaaggacaa ccaccuccuc ggcaccuucg     1500

accucaccgg cauccccccc gccccccgcg gcguccccca gaucgagguc accuucgaga     1560

ucgacgucaa cggcauccuc cgcgucaccg ccgaggacaa gggcaccggc aacaagaaca     1620

agaucaccau caccaacgac cagaaccgcc ucacccccga ggagaucgag cgcaugguca     1680

acgacgccga gaaguucgcc gaggaggaca agaagcucaa ggagcgcauc gacacccgca     1740

acgagcucga guccuacgcc uacucccuca agaaccagau cggcgacaag gagaagcucg     1800

gcggcaagcu cuccuccgag gacaaggaga ccauggagaa ggccgucgag gagaagaucg     1860

aguggcucga gucccaccag gacgccgaca ucgaggacuu caaggccaag aagaaggagc     1920

ucgaggagau cguccagccc aucaucucca agcucuacgg cuccgccggc ccccccccca     1980

ccggcgagga ggacaccgcc gagaaggacg agcucugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  2836
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt2)

<400>  2836
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

ccccccgcga gcucgccguc ggcaucgacc ucggcaccac cuacuccugc gucggcgucu      120

uccagcaggg ccgcgucgag auccucgcca acgaccaggg caaccgcacc acccccuccu      180

acgucgccuu caccgacacc gagcgccucg ucggcgacgc cgccaagucc caggccgccc      240

ucaaccccca caacaccguc uucgacgcca agcgccucau cggccgcaag uucgccgaca      300

ccaccgucca guccgacaug aagcacuggc ccuuccgcgu cgucuccgag ggcggcaagc      360

ccaagguccg cgucugcuac cgcggcgagg acaagaccuu cuaccccgag gagaucuccu      420

ccaugguccu cuccaagaug aaggagaccg ccgaggccua ccucggccag cccgucaagc      480

acgccgucau caccgucccc gccuacuuca acgacuccca gcgccaggcc accaaggacg      540

ccggcgccau cgccggccuc aacguccucc gcaucaucaa cgagcccacc gccgccgcca      600

ucgccuacgg ccucgaccgc cgcggcgccg gcgagcgcaa cguccucauc uucgaccucg      660

gcggcggcac cuucgacguc uccguccucu ccaucgacgc cggcgucuuc gaggucaagg      720

ccaccgccgg cgacacccac cucggcggcg aggacuucga caaccgccuc gucaaccacu      780

ucauggagga guuccgccgc aagcacggca aggaccucuc cggcaacaag cgcgcccucc      840

gccgccuccg caccgccugc gagcgcgcca agcgcacccu cuccuccucc acccaggcca      900

cccucgagau cgacucccuc uucgagggcg ucgacuucua caccuccauc acccgcgccc      960

gcuucgagga gcucugcucc gaccucuucc gcuccacccu cgagcccguc gagaaggccc     1020

uccgcgacgc caagcucgac aaggcccaga uccacgacgu cguccucguc ggcggcucca     1080

cccgcauccc caagguccag aagcuccucc aggacuucuu caacggcaag gagcucaaca     1140

aguccaucaa ccccgacgag gccgucgccu acggcgccgc cguccaggcc gccguccuca     1200

ugggcgacaa gugcgagaag guccaggacc uccuccuccu cgacgucgcc ccccucuccc     1260

ucggccucga gaccgccggc ggcgucauga ccacccucau ccagcgcaac gccaccaucc     1320

ccaccaagca gacccagacc uucaccaccu acuccgacaa ccagcccggc gucuucaucc     1380

aggucuacga gggcgagcgc gccaugacca aggacaacaa ccuccucggc cgcuucgagc     1440

ucuccggcau cccccccgcc ccccgcggcg ucccccagau cgaggucacc uucgacaucg     1500

acgccaacgg cauccucucc gucaccgcca ccgaccgcuc caccggcaag gccaacaaga     1560

ucaccaucac caacgacaag ggccgccucu ccaaggagga ggucgagcgc augguccacg     1620

aggccgagca guacaaggcc gaggacgagg cccagcgcga ccgcgucgcc gccaagaacu     1680

cccucgaggc ccacgucuuc cacgucaagg gcucccucca ggaggagucc cuccgcgaca     1740

agauccccga ggaggaccgc cgcaagaugc aggacaagug ccgcgagguc cucgccuggc     1800

ucgagcacaa ccagcucgcc gagaaggagg aguacgagca ccagaagcgc gagcucgagc     1860

agaucugccg ccccaucuuc ucccgccucu acggcggccc cggcgucccc ggcggcuccu     1920

ccugcggcac ccaggcccgc cagggcgacc ccuccaccgg ccccaucauc gaggaggucg     1980

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  2837
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt2)

<400>  2837
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

ccccccgcga gcucgccguc ggcaucgacc ucggcaccac cuacuccugc gucggcgucu      120

uccagcaggg ccgcgucgag auccucgcca acgaccaggg caaccgcacc acccccuccu      180

acgucgccuu caccgacacc gagcgccucg ucggcgacgc cgccaagucc caggccgccc      240

ucaaccccca caacaccguc uucgacgcca agcgccucau cggccgcaag uucgccgaca      300

ccaccgucca guccgacaug aagcacuggc ccuuccaggu cgucuccgag ggcggcaagc      360

ccaagguccg cgucugcuac cgcggcgagg acaagaccuu cuaccccgag gagaucuccu      420

ccaugguccu cuccaagaug aaggagaccg ccgaggccua ccucggccag cccgucaagc      480

acgccgucau caccgucccc accuacuucu ccaacuccca gcgccaggcc accaaggacg      540

ccggcgccau cgccggccuc aagguccucc ccaucaucaa cgaggccacc gccgccgcca      600

ucgccuacgg ccucgaccgc cgcggcgccg gcaagcgcaa cguccucauc uucgaccucg      660

gcggcggcac cuucgacguc uccguccucu ccaucgacgc cggcgucuuc gaggucaagg      720

ccaccgccgg cgacacccac cucggcggcg aggacuucga caaccgccuc gucaaccacu      780

ucauggagga guuccgccgc aagcacggca aggaccucuc cggcaacaag cgcgcccucc      840

gccgccuccg caccgccugc gagcgcgcca agcgcacccc cuccuccucc acccaggcca      900

cccucgagau cgacucccuc uucgagggcg ucgacuucua caaguccauc acccgcgccc      960

gcuucgagga gcucugcucc gaccucuucc gcuccacccu cgagcccguc gagaaggccc     1020

uccgcgacgc caagcucgac aaggcccaga uccacgacuu cguccucggc ggcggccucc     1080

acucccaccc ccagggcgcc gaggucgccg ccggccuccu ccagcgccag ggcgccgagc     1140

aggagcacca gcccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  2838
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt2)

<400>  2838
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucca       60

agggccccgc cgucggcauc gaccucggca ccaccuacuc cugcgucggc gucuuccagc      120

acggcaaggu cgagaucauc gccaacgacc agggcaaccg caccaccccc uccuacgucg      180

ccuucaccga caccgagcgc cucaucggcg acgccgccaa gaaccagguc gccaugaacc      240

ccaccaacac cgucuucgac gccaagcgcc ucaucggccg ccgcuucgac gacgccgucg      300

uccaguccga caugaagcac uggcccuuca uggucgucaa cgacgccggc cgccccaagg      360

uccaggucga guacaagggc gagaccaagu ccuucuaccc cgaggagguc uccuccaugg      420

uccucaccaa gaugaaggag aucgccgagg ccuaccucgg caagaccguc accaacgccg      480

ucgucaccgu ccccgccuac uucaacgacu cccagcgcca ggccaccaag gacgccggca      540

ccaucgccgg ccucaacguc cuccgcauca ucaacgagcc caccgccgcc gccaucgccu      600

acggccucga caagaagguc ggcgccgagc gcaacguccu caucuucgac cucggcggcg      660

gcaccuucga cgucuccauc cucaccaucg aggacggcau cuucgagguc aaguccaccg      720

ccggcgacac ccaccucggc ggcgaggacu ucgacaaccg cauggucaac cacuucaucg      780

ccgaguucaa gcgcaagcac aagaaggaca ucuccgagaa caagcgcgcc guccgccgcc      840

uccgcaccgc cugcgagcgc gccaagcgca cccucuccuc cuccacccag gccuccaucg      900

agaucgacuc ccucuacgag ggcaucgacu ucuacaccuc caucacccgc gcccgcuucg      960

aggagcucaa cgccgaccuc uuccgcggca cccucgaccc cgucgagaag gcccuccgcg     1020

acgccaagcu cgacaagucc cagauccacg acaucguccu cgucggcggc uccacccgca     1080

uccccaagau ccagaagcuc cuccaggacu ucuucaacgg caaggagcuc aacaagucca     1140

ucaaccccga cgaggccguc gccuacggcg ccgccgucca ggccgccauc cucuccggcg     1200

acaaguccga gaacguccag gaccuccucc uccucgacgu caccccccuc ucccucggca     1260

ucgagaccgc cggcggcguc augaccgucc ucaucaagcg caacaccacc auccccacca     1320

agcagaccca gaccuucacc accuacuccg acaaccagcc cggcguccuc auccaggucu     1380

acgagggcga gcgcgccaug accaaggaca acaaccuccu cggcaaguuc gagcucaccg     1440

gcaucccccc cgccccccgc ggcguccccc agaucgaggu caccuucgac aucgacgcca     1500

acggcauccu caacgucucc gccgucgaca aguccaccgg caaggagaac aagaucacca     1560

ucaccaacga caagggccgc cucuccaagg aggacaucga gcgcaugguc caggaggccg     1620

agaaguacaa ggccgaggac gagaagcagc gcgacaaggu cuccuccaag aacucccucg     1680

aguccuacgc cuucaacaug aaggccaccg ucgaggacga gaagcuccag ggcaagauca     1740

acgacgagga caagcagaag auccucgaca agugcaacga gaucaucaac uggcucgaca     1800

agaaccagac cgccgagaag gaggaguucg agcaccagca gaaggagcuc gagaaggucu     1860

gcaaccccau caucaccaag cucuaccagu ccgccggcgg caugcccggc ggcaugcccg     1920

gcggcuuccc cggcggcggc gccccccccu ccggcggcgc cuccuccggc cccaccaucg     1980

aggaggucga cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  2839
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt2)

<400>  2839
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaucu       60

ccgccucccg cgccgccgcc gcccgccucg ucggcgccgc cgccucccgc ggccccaccg      120

ccgcccgcca ccaggacucc uggaacggcc ucucccacga ggccuuccgc cucgucuccc      180

gccgcgacua cgccuccgag gccaucaagg gcgccgucgu cggcaucgac cucggcacca      240

ccaacuccug cgucgccguc auggagggca agcaggccaa gguccucgag aacgccgagg      300

gcgcccgcac cacccccucc gucgucgccu ucaccgccga cggcgagcgc cucgucggca      360

ugcccgccaa gcgccaggcc gucaccaacc ccaacaacac cuucuacgcc accaagcgcc      420

ucaucggccg ccgcuacgac gaccccgagg uccagaagga caucaagaac guccccuuca      480

agaucguccg cgccuccaac ggcgacgccu gggucgaggc ccacggcaag cucuacuccc      540

ccucccagau cggcgccuuc guccucauga agaugaagga gaccgccgag aacuaccucg      600

gccacaccgc caagaacgcc gucaucaccg uccccgccua cuucaacgac ucccagcgcc      660

aggccaccaa ggacgccggc cagaucuccg gccucaacgu ccuccgcguc aucaacgagc      720

ccaccgccgc cgcccucgcc uacggccucg acaaguccga ggacaagguc aucgccgucu      780

acgaccucgg cggcggcacc uucgacaucu ccauccucga gauccagaag ggcgucuucg      840

aggucaaguc caccaacggc gacaccuucc ucggcggcga ggacuucgac caggcccucc      900

uccgccacau cgucaaggag uucaagcgcg agaccggcgu cgaccucacc aaggacaaca      960

uggcccucca gcgcguccgc gaggccgccg agaaggccaa gugcgagcuc uccuccuccg     1020

uccagaccga caucaaccuc cccuaccuca ccauggacuc cuccggcccc aagcaccuca     1080

acaugaagcu cacccgcgcc caguucgagg gcaucgucac cgaccucauc cgccgcacca     1140

ucgcccccug ccagaaggcc augcaggacg ccgaggucuc caaguccgac aucggcgagg     1200

ucauccucgu cggcggcaug acccgcaugc ccaaggucca gcagaccguc caggaccucu     1260

ucggccgcgc ccccuccaag gccgucaacc ccgacgaggc cgucgccauc ggcgccgcca     1320

uccagggcgg cguccucgcc ggcgacguca ccgacguccu ccuccucgac gucacccccc     1380

ucucccucgg caucgagacc cucggcggcg ucuucaccaa gcucaucaac cgcaacacca     1440

ccauccccac caagaagucc caggucuucu ccaccgccgc cgacggccag acccaggucg     1500

agaucaaggu cugccagggc gagcgcgaga uggccggcga caacaagcuc cucggccagu     1560

ucacccucau cggcaucccc cccgcccccc gcggcguccc ccagaucgag gucaccuucg     1620

acaucgacgc caacggcauc guccacgucu ccgccaagga caagggcacc ggccgcgagc     1680

agcagaucgu cauccagucc uccggcggcc ucuccaagga cgacaucgag aacaugguca     1740

agaacgccga gaaguacgcc gaggaggacc gccgcaagaa ggagcgcguc gaggccguca     1800

acauggccga gggcaucauc cacgacaccg agaccaagau ggaggaguuc aaggaccagc     1860

uccccgccga cgagugcaac aagcucaagg aggagaucuc caagaugcgc gagcuccucg     1920

cccgcaagga cuccgagacc ggcgagaaca uccgccaggc cgccuccucc cuccagcagg     1980

ccucccucaa gcucuucgag auggccuaca agaagauggc cuccgagcgc gagggcuccg     2040

gcuccuccgg caccggcgag cagaaggagg accagaagga ggagaagcag ugaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  2840
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt2)

<400>  2840
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaggaggc cggcggcucc gacggccccc gcgagaccgc ccccaccucc gccuacuccu      120

cccccgcccg cucccucggc gacaccggca ucaccccccu cucccccucc cacaucguca      180

acgacaccga cuccaacguc uccgagcagc aguccuuccu cgucgucguc gccgucgacu      240

ucggcaccac cuccuccggc uacgccuacu ccuucaccaa ggagcccgag ugcauccacg      300

ucaugcgccg cugggagggc ggcgaccccg gcgucuccaa ccagaagacc cccaccacca      360

uccuccucac ccccgagcgc aaguuccacu ccuucggcua cgccgcccgc gacuucuacc      420

acgaccucga ccccaacgag gccaagcagu ggcucuaccu cgagaaguuc aagaugaagc      480

uccacaccac cggcgaccuc accauggaca ccgaccucac cgccgccaac ggcaagaagg      540

ucaaggcccu cgagaucuuc gccuacgccc uccaguacuu caaggagcag gcccucaagg      600

agcucuccga ccaggccggc uccgaguucg agaacuccga cguccgcugg gucaucaccg      660

uccccgccau cuggaagcag cccgccaagc aguucaugcg ccaggccgcc uaccaggccg      720

gccucgccuc ccccgagaac uccgagcagc ucaucaucgc ccucgagccc gaggccgccu      780

ccaucuacug ccgcaagcuc cgccuccacc agaugaucga gcucuccucc aaggccgccg      840

ucaacggcua cuccggcucc gacaccgucg gcgccggcuu cacccaggcc aaggagcaca      900

uccgccgcaa ccgccagucc cgcaccuucc ucgucgagaa cgucaucggc gagaucuggu      960

ccgagcucga ggagggcgac aaguacgucg ucgucgacuc cggcggcggc accgucgacc     1020

ucaccgucca ccagauccgc cuccccgagg gccaccucaa ggagcucuac aaggccaccg     1080

gcggccccua cggcucccuc ggcgucgacu acgaguucga gaagcuccuc uacaagaucu     1140

ucggcgagga cuucaucgag caguucaaga ucaagcgccc cgccgccugg gucgaccuca     1200

ugaucgccuu cgagucccgc aagcgcgccg ccgcccccga ccgcaccaac ccccucaaca     1260

ucacccuccc cuucuccuuc aucgacuacu acaagaaguu ccgcggccac uccgucgagc     1320

acgcccuccg caaguccaac gucgacuucg ucaagugguc cucccagggc augcuccgca     1380

ugucccccga cgccaugaac gcccucuuca agcccaccau cgacuccauc aucgagcacc     1440

uccgcgaccu cuuccagaag cccgaggucu ccaccgucaa guuccucuuc cucgucggcg     1500

gcuucgccga ggccccccuc cuccagcagg ccguccaggc cgccuucggc gaccagugcc     1560

gcaucaucau cccccaggac gucggccuca ccauccucaa gggcgccguc cucuucggcc     1620

ucgaccccgc cgucaucaag guccgccgcu ccccccucac cuacggcguc ggcguccuca     1680

accgcuacgu cgagggcaag cacccccccg agaagcuccu cgucaaggac ggcacccgcu     1740

ggugcaccga cgucuucgac aaguucaucu ccgccgacca guccgucgcc cucggcgagc     1800

ucgucaagcg cuccuacacc cccgccaagc ccucccagcu cgucaucguc aucaacaucu     1860

acuccuccga gcacgacaac gucuccuuca ucaccgaccc cggcgucaag aagugcggca     1920

cccuccgccu cgaccucacc ggcaccuccg gcaccgccgu ccccgcccgc cgcgagaucc     1980

agacccucau gcaguucggc gacaccgaga ucaaggccac cgccaucgac aucgccaccu     2040

ccaaguccgu caaggucggc aucgacuucc ucaacuacug aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  2841
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt2)

<400>  2841
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcucg       60

ccguccccga gaugggccuc cagggccucu acaucggcuc cucccccgag cgcucccccg      120

uccccucccc ccccggcucc ccccgcaccc aggaguccug cggcaucgcc ccccucaccc      180

ccucccaguc ccccaagccc gagguccgcg ccccccagca ggccuccuuc uccgucgucg      240

ucgccaucga cuucggcacc accuccuccg gcuacgccuu cuccuucgcc uccgaccccg      300

aggccaucca caugaugcgc aagugggagg gcggcgaccc cggcgucgcc caccagaaga      360

cccccaccug ccuccuccuc acccccgagg gcgccuucca cuccuucggc uacaccgccc      420

gcgacuacua ccacgaccuc gaccccgagg aggcccgcga cuggcucuac uucgagaagu      480

ucaagaugaa gauccacucc gccaccgacc ucacccucaa gacccagcuc gaggccguca      540

acggcaagac caugcccgcc cucgaggucu ucgcccacgc ccuccgcuuc uuccgcgagc      600

acgcccucca ggagcuccgc gagcaguccc ccucccuccc cgagaaggac accguccgcu      660

ggguccucac cguccccgcc aucuggaagc agcccgccaa gcaguucaug cgcgaggccg      720

ccuaccucgc cggccucguc ucccgcgaga acgccgagca gcuccucauc gcccucgagc      780

ccgaggccgc cuccgucuac ugccgcaagc uccgccucca ccagcuccuc gaccucuccg      840

gccgcgcccc cggcggcggc cgccucggcg agcgccgcuc caucgacucc uccuuccgcc      900

aggcccgcga gcagcuccgc cgcucccgcc acucccgcac cuuccucguc gaguccggcg      960

ucggcgagcu cugggccgag augcaggccg gcgaccgcua cgucgucgcc gacugcggcg     1020

gcggcaccgu cgaccucacc guccaccagc ucgagcagcc ccacggcacc cucaaggagc     1080

ucuacaaggc cuccggcggc cccuacggcg ccgucggcgu cgaccucgcc uucgagcagc     1140

uccucugccg caucuucggc gaggacuuca ucgccaccuu caagcgccag cgccccgccg     1200

ccugggucga ccucaccauc gccuucgagg cccgcaagcg caccgccggc ccccaccgcg     1260

ccggcgcccu caacaucucc cuccccuucu ccuucaucga cuucuaccgc aagcagcgcg     1320

gccacaacgu cgagaccgcc cuccgccgcu ccuccgucaa cuucgucaag ugguccuccc     1380

agggcaugcu ccgcaugucc ugcgaggcca ugaacgagcu cuuccagccc accgucuccg     1440

gcaucaucca gcacaucgag gcccuccucg cccgccccga gguccagggc gucaagcucc     1500

ucuuccucgu cggcggcuuc gccgaguccg ccguccucca gcacgccguc caggccgccc     1560

ucggcgcccg cggccuccgc gucgucgucc cccacgacgu cggccucacc auccucaagg     1620

gcgccguccu cuucggccag gcccccggcg ucguccgcgu ccgccgcucc ccccucaccu     1680

acggcgucgg cguccucaac cgcuucgucc ccggccgcca cccccccgag aagcuccucg     1740

uccgcgacgg ccgccgcugg ugcaccgacg ucuucgagcg cuucgucgcc gccgagcagu     1800

ccgucgcccu cggcgaggag guccgccgcu ccuacugccc cgcccgcccc ggccagcgcc     1860

gcguccucau caaccucuac ugcugcgccg ccgaggacgc ccgcuucauc accgaccccg     1920

gcguccgcaa gugcggcgcc cucucccucg agcucgagcc cgccgacugc ggccaggaca     1980

ccgccggcgc cccccccggc cgccgcgaga uccgcgccgc caugcaguuc ggcgacaccg     2040

agaucaaggu caccgccguc gacgucucca ccaaccgcuc cguccgcgcc uccaucgacu     2100

uccucuccaa cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  2842
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt2)

<400>  2842
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

gcgagaugac cauccucggc uccgccgucc ucacccuccu ccucgccggc uaccucgccc      120

agcaguaccu cccccucccc acccccaagg ucaucggcau cgaccucggc accaccuacu      180

gcuccgucgg cgucuucuuc cccggcaccg gcaaggucaa ggucaucccc gacgagaacg      240

gccacaucuc cauccccucc auggucuccu ucaccgacaa cgacgucuac gucggcuacg      300

aguccgucga gcucgccgac uccaaccccc agaacaccau cuacgacgcc aagcgcuuca      360

ucggcaagau cuucaccgcc gaggagcucg aggccgagau cggccgcuac cccuucaagg      420

uccucaacaa gaacggcaug gucgaguucu ccgucaccuc caacgagacc aucaccgucu      480

cccccgagua cgucggcucc cgccuccucc ucaagcucaa ggagauggcc gaggccuacc      540

ucggcaugcc cgucgccaac gccgucaucu ccguccccgc cgaguucgac cucaagcagc      600

gcaacuccac caucgaggcc gccaaccucg ccggccucaa gauccuccgc gucaucaacg      660

agcccaccgc cgccgccaug gccuacggcc uccacaaggc cgacgucuuc cacguccucg      720

ucaucgaccu cggcggcggc acccucgacg ucucccuccu caacaagcag ggcggcaugu      780

uccucacccg cgccaugucc ggcaacaaca agcucggcgg ccaggacuuc aaccagcgcc      840

uccuccagua ccucuacaag cagaucuacc agaccuacgg cuucgucccc ucccgcaagg      900

aggagaucca ccgccuccgc caggccgucg agauggucaa gcucaaccuc acccuccacc      960

aguccgccca gcucuccguc cuccucaccg ucgaggagca ggaccgcaag gagccccacu     1020

ccuccgacac cgagcucccc aaggacaagc ucuccuccgc cgacgaccac cgcgucaacu     1080

ccggcuucgg ccgcggccuc uccgacaaga aguccggcga gucccagguc cucuucgaga     1140

ccgagaucuc ccgcaagcuc uucgacaccc ucaacgagga ccucuuccag aagauccucg     1200

uccccaucca gcagguccuc aaggagggcc accucgagaa gaccgagauc gacgaggucg     1260

uccucgucgg cggcuccacc cgcauccccc gcauccgcca ggucauccag gaguucuucg     1320

gcaaggaccc caacaccucc gucgaccccg accucgccgu cgucaccggc gucgccaucc     1380

aggccggcau cgacggcggc uccuggcccc uccaggucuc cgcccucgag auccccaaca     1440

agcaccucca gaagaccaac uucaacugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  2843
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt2)

<400>  2843
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ccaucggcgu ccaccucggc ugcaccuccg ccugcgucgc cgucuacaag gacggccgcg      120

ccggcgucgu cgccaacgac gccggcgacc gcgucacccc cgccgucguc gccuacuccg      180

agaacgagga gaucgucggc cucgccgcca agcagucccg cauccgcaac aucuccaaca      240

ccgucaugaa ggucaagcag auccucggcc gcuccuccuc cgacccccag gcccagaagu      300

acaucgccga guccaagugc cucgucaucg agaagaacgg caagcuccgc uacgagaucg      360

acaccggcga ggagaccaag uucgucaacc ccgaggacgu cgcccgccuc aucuucucca      420

agaugaagga gaccgcccac uccguccucg gcuccgacgc caacgacguc gucaucaccg      480

uccccuucga cuucggcgag aagcagaaga acgcccucgg cgaggccgcc cgcgccgccg      540

gcuucaacgu ccuccgccuc auccacgagc ccuccgccgc ccuccucgcc uacggcaucg      600

gccaggacuc ccccaccggc aaguccaaca uccucgucuu caagcucggc ggcaccuccc      660

ucucccucuc cgucauggag gucaacuccg gcaucuaccg cguccucucc accaacaccg      720

acgacaacau cggcggcgcc cacuucaccg agacccucgc ccaguaccuc gccuccgagu      780

uccagcgcuc cuucaagcac gacguccgcg gcaacgcccg cgccaugaug aagcucacca      840

acuccgccga ggucgccaag cacucccucu ccacccucgg cuccgccaac ugcuuccucg      900

acucccucua cgagggccag gacuucgacu gcaacgucuc ccgcgcccgc uucgagcucc      960

ucugcucccc ccucuucaac aagugcaucg aggccauccg cggccuccuc gaccagaacg     1020

gcuucaccgc cgacgacauc aacaaggucg uccucugcgg cggcuccucc cgcaucccca     1080

agcuccagca gcucaucaag gaccucuucc ccgccgucga gcuccucaac uccauccccc     1140

ccgacgaggu cauccccauc ggcgccgcca ucgaggccgg cauccucauc ggcaaggaga     1200

accuccucgu cgaggacucc cucaugaucg agugcuccgc ccgcgacauc cucgucaagg     1260

gcgucgacga guccggcgcc ucccgcuuca ccguccucuu ccccuccggc accccccucc     1320

ccgcccgccg ccagcacacc cuccaggccc ccggcuccau cuccuccguc ugccucgagc     1380

ucuacgaguc cgacggcaag aacuccgcca aggaggagac caaguucgcc caggucgucc     1440

uccaggaccu cgacaagaag gagaacggcc uccgcgacau ccucgccguc cucaccauga     1500

agcgcgacgg cucccuccac gucaccugca ccgaccagga gaccggcaag ugcgaggcca     1560

ucuccaucga gaucgccucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  2844
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt2)

<400>  2844
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccg       60

ucgucggccu cgacgucggc ucccaguccu gcuacaucgc cgucgcccgc gccggcggca      120

ucgagaccau cgccaacgag uucuccgacc gcugcacccc cuccgucauc uccuucggcu      180

ccaagaaccg caccaucggc gucgccgcca agaaccagca gaucacccac gccaacaaca      240

ccgucuccaa cuucaagcgc uuccacggcc gcgccuucaa cgaccccuuc auccagaagg      300

agaaggagaa ccucuccuac gaccucgucc cccucaagaa cggcggcguc ggcaucaagg      360

ucauguacau gggcgaggag caccucuucu ccgucgagca gaucaccgcc augcuccuca      420

ccaagcucaa ggagaccgcc gagaacuccc ucaagaagcc cgucaccgac ugcgucaucu      480

ccguccccuc cuucuucacc gacgccgagc gccgcuccgu ccucgacgcc gcccagaucg      540

ucggccucaa cugccuccgc cucaugaacg acaugaccgc cgucgcccuc aacuacggca      600

ucuacaagca ggaccucccc ucccucgacg agaagccccg caucgucguc uucgucgaca      660

ugggccacuc cgccuuccag gucuccgccu gcgccuucaa caagggcaag cucaaggucc      720

ucggcaccgc cuucgacccc uuccucggcg gcaagaacuu cgacgagaag cucgucgagc      780

acuucugcgc cgaguucaag accaaguaca agcucgacgc caaguccaag auccgcgccc      840

uccuccgccu cuaccaggag ugcgagaagc ucaagaagcu cauguccucc aacuccaccg      900

accucccccu caacaucgag ugcuucauga acgacaagga cgucuccggc aagaugaacc      960

gcucccaguu cgaggagcuc ugcgccgagc uccuccagaa gaucgagguc ccccucuacu     1020

cccuccucga gcagacccac cucaaggucg aggacgucuc cgccgucgag aucgucggcg     1080

gcgccacccg cauccccgcc gucaaggagc gcaucgccaa guucuucggc aaggacaucu     1140

ccaccacccu caacgccgac gaggccgucg cccgcggcug cgcccuccag ugcgccaucc     1200

ucucccccgc cuucaagguc cgcgaguucu ccgucaccga cgccgucccc uuccccaucu     1260

cccucaucug gaaccacgac uccgaggaca ccgagggcgu ccacgagguc uucucccgca     1320

accacgccgc ccccuucucc aagguccuca ccuuccuccg ccgcggcccc uucgagcucg     1380

aggccuucua cuccgacccc cagggcgucc ccuaccccga ggccaagauc ggccgcuucg     1440

ucguccagaa cgucuccgcc cagaaggacg gcgagaaguc ccgcgucaag gucaaggucc     1500

gcgucaacac ccacggcauc uucaccaucu ccaccgccuc cauggucgag aaggucccca     1560

ccgaggagaa cgagaugucc uccgaggccg acauggagug ccucaaccag cgcccccccg     1620

agaaccccga caccgacaag aacguccagc aggacaacuc cgaggccggc acccagcccc     1680

agguccagac cgacgcccag cagaccuccc aguccccccc cucccccgag cucaccuccg     1740

aggagaacaa gauccccgac gccgacaagg ccaacgagaa gaaggucgac cagccccccg     1800

aggccaagaa gcccaagauc aaggucguca acgucgagcu ccccaucgag gccaaccucg     1860

ucuggcagcu cggcaaggac cuccucaaca uguacaucga gaccgagggc aagaugauca     1920

ugcaggacaa gcucgagaag gagcgcaacg acgccaagaa cgccgucgag gaguacgucu     1980

acgaguuccg cgacaagcuc ugcggccccu acgagaaguu caucugcgag caggaccacc     2040

agaacuuccu ccgccuccuc accgagaccg aggacuggcu cuacgaggag ggcgaggacc     2100

aggccaagca ggccuacguc gacaagcucg aggagcucau gaagaucggc acccccguca     2160

agguccgcuu ccaggaggcc gaggagcgcc ccaagauguu cgaggagcuc ggccagcgcc     2220

uccagcacua cgccaagauc gccgccgacu uccgcaacaa ggacgagaag uacaaccaca     2280

ucgacgaguc cgagaugaag aaggucgaga aguccgucaa cgaggucaug gaguggauga     2340

acaacgucau gaacgcccag gccaagaagu cccucgacca ggaccccguc guccgcgccc     2400

aggagaucaa gaccaagauc aaggagcuca acaacaccug cgagcccguc gucacccagc     2460

ccaagcccaa gaucgagucc cccaagcucg agcgcacccc caacggcccc aacaucgaca     2520

agaaggagga ggaccucgag gacaagaaca acuucggcgc cgagcccccc caccagaacg     2580

gcgagugcua ccccaacgag aagaacuccg ucaacaugga ccucgacuga ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  2845
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt2)

<400>  2845
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaagguccg ccgccagcgc ccccgccgcc gcgucugcug ggcccucguc gccguccucc      120

ucgccgaccu ccucgcccuc uccgacaccc ucgccgucau guccgucgac cucggcuccg      180

aguccaugaa ggucgccauc gucaagcccg gcguccccau ggagaucguc cucaacaagg      240

agucccgccg caagaccccc gucaucguca cccucaagga gaacgagcgc uucuucggcg      300

acuccgccgc cuccauggcc aucaagaacc ccaaggccac ccuccgcuac uuccagcacc      360

uccucggcaa gcaggccgac aacccccacg ucgcccucua ccaggcccgc uuccccgagc      420

acgagcucac cuucgacccc cagcgccaga ccguccacuu ccagaucucc ucccagcucc      480

aguucucccc cgaggagguc cucggcaugg uccucaacua cucccgcucc cucgccgagg      540

acuucgccga gcagcccauc aaggacgccg ucaucaccgu ccccgucuuc uucaaccagg      600

ccgagcgccg cgccguccuc caggccgccc gcauggccgg ccucaagguc cuccagcuca      660

ucaacgacaa caccgccacc gcccucuccu acggcgucuu ccgccgcaag gacaucaaca      720

ccaccgccca gaacaucaug uucuacgaca ugggcuccgg cuccaccguc ugcaccaucg      780

ucaccuacca gauggucaag accaaggagg ccggcaugca gccccagcuc cagauccgcg      840

gcgucggcuu cgaccgcacc cucggcggcc ucgagaugga gcuccgccuc cgcgagcgcc      900

ucgccggccu cuucaacgag cagcgcaagg gccagcgcgc caaggacguc cgcgagaacc      960

cccgcgccau ggccaagcuc cuccgcgagg ccaaccgccu caagaccguc cucuccgcca     1020

acgccgacca cauggcccag aucgagggcc ucauggacga cgucgacuuc aaggccaagg     1080

ucacccgcgu cgaguucgag gagcucugcg ccgaccucuu cgagcgcguc cccggccccg     1140

uccagcaggc ccuccagucc gccgagaugu cccucgacga gaucgagcag gucauccucg     1200

ucggcggcgc cacccgcguc ccccgcgucc aggagguccu ccucaaggcc gucggcaagg     1260

aggagcucgg caagaacauc aacgccgacg aggccgccgc caugggcgcc gucuaccagg     1320

ccgccgcccu cuccaaggcc uucaagguca agcccuucgu cguccgcgac gccgucgucu     1380

accccauccu cgucgaguuc acccgcgagg ucgaggagga gcccggcauc cacucccuca     1440

agcacaacaa gcgcguccuc uucucccgca ugggccccua cccccagcgc aaggucauca     1500

ccuucaaccg cuacucccac gacuucaacu uccacaucaa cuacggcgac cucggcuucc     1560

ucggccccga ggaccuccgc gucuucggcu cccagaaccu caccaccguc aagcucaagg     1620

gcgucggcga cuccuucaag aaguaccccg acuacgaguc caagggcauc aaggcccacu     1680

ucaaccucga cgaguccggc guccucuccc ucgaccgcgu cgaguccguc uucgagaccc     1740

ucgucgagga cuccgccgag gaggagucca cccucaccaa gcucggcaac accaucuccu     1800

cccucuucgg cggcggcacc acccccgacg ccaaggagaa cggcaccgac accguccagg     1860

aggaggagga gucccccgcc gagggcucca aggacgagcc cggcgagcag gucgagcuca     1920

aggaggaggc cgaggccccc gucgaggacg gcucccagcc cccccccccc gagcccaagg     1980

gcgacgccac ccccgagggc gagaaggcca ccgagaagga gaacggcgac aaguccgagg     2040

cccagaagcc cuccgagaag gccgaggccg gccccgaggg cgucgccccc gcccccgagg     2100

gcgagaagaa gcagaagccc gcccgcaagc gccgcauggu cgaggagauc ggcgucgagc     2160

ucgucguccu cgaccucccc gaccuccccg aggacaagcu cgcccagucc guccagaagc     2220

uccaggaccu cacccuccgc gaccucgaga agcaggagcg cgagaaggcc gccaacuccc     2280

ucgaggccuu caucuucgag acccaggaca agcucuacca gcccgaguac caggaggucu     2340

ccaccgagga gcagcgcgag gagaucuccg gcaagcucuc cgccgccucc accuggcucg     2400

aggacgaggg cgucggcgcc accaccguca ugcucaagga gaagcucgcc gagcuccgca     2460

agcucugcca gggccucuuc uuccgcgucg aggagcgcaa gaaguggccc gagcgccucu     2520

ccgcccucga caaccuccuc aaccacuccu ccauguuccu caagggcgcc cgccucaucc     2580

ccgagaugga ccagaucuuc accgaggucg agaugaccac ccucgagaag gucaucaacg     2640

agaccugggc cuggaagaac gccacccucg ccgagcaggc caagcucccc gccaccgaga     2700

agcccguccu ccucuccaag gacaucgagg ccaagaugau ggcccucgac cgcgaggucc     2760

aguaccuccu caacaaggcc aaguucacca agccccgccc ccgccccaag gacaagaacg     2820

gcacccgcgc cgagcccccc cucaacgccu ccgccuccga ccagggcgag aaggucaucc     2880

cccccgccgg ccagaccgag gacgccgagc ccaucuccga gcccgagaag gucgagaccg     2940

gcuccgagcc cggcgacacc gagccccucg agcucggcgg ccccggcgcc gagcccgagc     3000

agaaggagca guccaccggc cagaagcgcc cccucaagaa cgacgagcuc ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  2846
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt2)

<400>  2846
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggagaccca gacccaggac cagcccaugg aggaggagga ggucgagacc uucgccuucc      120

aggccgagau cgcccagcuc augucccuca ucaucaacac cuucuacucc aacaaggaga      180

ucuuccuccg cgagcucauc uccaacuccu ccgacgcccu cgacaagauc cgcuacgagu      240

cccucaccga ccccuccaag cucgacuccg gcaaggagcu ccacaucaac cucaucccca      300

acaagcagga ccgcacccuc accaucgucg acaccggcau cggcaugacc aaggccgacc      360

ucaucaacaa ccucggcacc aucgccaagu ccggcaccaa ggccuucaug gaggcccucc      420

aggccggcgc cgacaucucc augaucggcc aguucggcgu cggcuucuac uccgccuacc      480

ucgucgccga gaaggucacc gucaucacca agcacaacga cgacgagcag uacgccuggg      540

aguccuccgc cggcggcucc uucaccgucc gcaccgacac cggcgagccc augggccgcg      600

gcaccaaggu cauccuccac cucaaggagg accagaccga guaccucgag gagcgccgca      660

ucaaggagau cgucaagaag cacucccagu ucaucggcua ccccaucacc cucuucgucg      720

agaaggagcg cgacaaggag gucuccgacg acgaggccga ggagaaggag gacaaggagg      780

aggagaagga gaaggaggag aaggaguccg aggacaagcc cgagaucgag gacgucggcu      840

ccgacgagga ggaggagaag aaggacggcg acaagaagaa gaagaagaag aucaaggaga      900

aguacaucga ccaggaggag cucaacaaga ccaagcccau cuggacccgc aaccccgacg      960

acaucaccaa cgaggaguac ggcgaguucu acaagucccu caccaacgac ugggaggacc     1020

accucgccgu caagcacuuc uccgucgagg gccagcucga guuccgcgcc cuccucuucg     1080

ucccccgccg cgcccccuuc gaccucuucg agaaccgcaa gaagaagaac aacaucaagc     1140

ucuacguccg ccgcgucuuc aucauggaca acugcgagga gcucaucccc gaguaccuca     1200

acuucauccg cggcgucguc gacuccgagg accucccccu caacaucucc cgcgagaugc     1260

uccagcaguc caagauccuc aaggucaucc gcaagaaccu cgucaagaag ugccucgagc     1320

ucuucaccga gcucgccgag gacaaggaga acuacaagaa guucuacgag caguucucca     1380

agaacaucaa gcucggcauc cacgaggacu cccagaaccg caagaagcuc uccgagcucc     1440

uccgcuacua caccuccgcc uccggcgacg agauggucuc ccucaaggac uacugcaccc     1500

gcaugaagga gaaccagaag cacaucuacu acaucaccgg cgagaccaag gaccaggucg     1560

ccaacuccgc cuucgucgag cgccuccgca agcacggccu cgaggucauc uacaugaucg     1620

agcccaucga cgaguacugc guccagcagc ucaaggaguu cgagggcaag acccucgucu     1680

ccgucaccaa ggagggccuc gagcuccccg aggacgagga ggagaagaag aagcaggagg     1740

agaagaagac caaguucgag aaccucugca agaucaugaa ggacauccuc gagaagaagg     1800

ucgagaaggu cgucgucucc aaccgccucg ucaccucccc cugcugcauc gucaccucca     1860

ccuacggcug gaccgccaac auggagcgca ucaugaaggc ccaggcccuc cgcgacaacu     1920

ccaccauggg cuacauggcc gccaagaagc accucgagau caaccccgac cacuccauca     1980

ucgagacccu ccgccagaag gccgaggccg acaagaacga caaguccguc aaggaccucg     2040

ucauccuccu cuacgagacc gcccuccucu ccuccggcuu cucccucgag gacccccaga     2100

cccacgccaa ccgcaucuac cgcaugauca agcucggccu cggcaucgac gaggacgacc     2160

ccaccgccga cgacaccucc gccgccguca ccgaggagau gcccccccuc gagggcgacg     2220

acgacaccuc ccgcauggag gaggucgacu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  2847
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt2)

<400>  2847
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

ccuccaagcu cgacuccggc aagggccucc acaucaaccu cguccccaac aagcagaacc      120

agacccucac caucgucgac acccgcaucg gcaugaccaa gaccgaccuc aucaacaacc      180

ucggcaccgu caccaagucc ggcaccaagg ccuucaugga ggcccuccag gccgacgccg      240

acaucuccau gaucggccac uucggcgucg gcuucuacuc cgccuaccuc gucgccaaga      300

aggucaccgu caucuccaag cacaacaacg acgagcagua caccugggag uccuccgccg      360

gcggcuccuu caccguccgc accgacgagu gaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  2848
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt2)

<400>  2848
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggaggucca ccacggcgag gaggaggucg agaccuucgc cuuccaggcc gagaucgccc      120

agcucauguc ccucaucauc aacaccuucu acuccaacaa ggagaucuuc cuccgcgagc      180

ucaucuccaa cgccuccgac gcccucgaca agauccgcua cgagucccuc accgaccccu      240

ccaagcucga cuccggcaag gagcucaaga ucgacaucau ccccaacccc caggagcgca      300

cccucacccu cgucgacacc ggcaucggca ugaccaaggc cgaccucauc aacaaccucg      360

gcaccaucgc caaguccggc accaaggccu ucauggaggc ccuccaggcc ggcgccgaca      420

ucuccaugau cggccaguuc ggcgucggcu ucuacuccgc cuaccucguc gccgagaagg      480

ucgucgucau caccaagcac aacgacgacg agcaguacgc cugggagucc uccgccggcg      540

gcuccuucac cguccgcgcc gaccacggcg agcccaucgg ccgcggcacc aaggucaucc      600

uccaccucaa ggaggaccag accgaguacc ucgaggagcg ccgcgucaag gaggucguca      660

agaagcacuc ccaguucauc ggcuacccca ucacccucua ccucgagaag gagcgcgaga      720

aggagaucuc cgacgacgag gccgaggagg agaagggcga gaaggaggag gaggacaagg      780

acgacgagga gaagcccaag aucgaggacg ucggcuccga cgaggaggac gacuccggca      840

aggacaagaa gaagaagacc aagaagauca aggagaagua caucgaccag gaggagcuca      900

acaagaccaa gcccaucugg acccgcaacc ccgacgacau cacccaggag gaguacggcg      960

aguucuacaa gucccucacc aacgacuggg aggaccaccu cgccgucaag cacuucuccg     1020

ucgagggcca gcucgaguuc cgcgcccucc ucuucauccc ccgccgcgcc cccuucgacc     1080

ucuucgagaa caagaagaag aagaacaaca ucaagcucua cguccgccgc gucuucauca     1140

uggacuccug cgacgagcuc auccccgagu accucaacuu cauccgcggc gucgucgacu     1200

ccgaggaccu cccccucaac aucucccgcg agaugcucca gcaguccaag auccucaagg     1260

ucauccgcaa gaacaucguc aagaagugcc ucgagcucuu cuccgagcuc gccgaggaca     1320

aggagaacua caagaaguuc uacgaggccu ucuccaagaa ccucaagcuc ggcauccacg     1380

aggacuccac caaccgccgc cgccucuccg agcuccuccg cuaccacacc ucccaguccg     1440

gcgacgagau gaccucccuc uccgaguacg ucucccgcau gaaggagacc cagaagucca     1500

ucuacuacau caccggcgag uccaaggagc aggucgccaa cuccgccuuc gucgagcgcg     1560

uccgcaagcg cggcuucgag gucgucuaca ugaccgagcc caucgacgag uacugcgucc     1620

agcagcucaa ggaguucgac ggcaaguccc ucgucuccgu caccaaggag ggccucgagc     1680

uccccgagga cgaggaggag aagaagaaga uggaggaguc caaggccaag uucgagaacc     1740

ucugcaagcu caugaaggag auccucgaca agaaggucga gaaggucacc aucuccaacc     1800

gccucgucuc cucccccugc ugcaucguca ccuccaccua cggcuggacc gccaacaugg     1860

agcgcaucau gaaggcccag gcccuccgcg acaacuccac caugggcuac augauggcca     1920

agaagcaccu cgagaucaac cccgaccacc ccaucgucga gacccuccgc cagaaggccg     1980

aggccgacaa gaacgacaag gccgucaagg accucgucgu ccuccucuuc gagaccgccc     2040

uccucuccuc cggcuucucc cucgaggacc cccagaccca cuccaaccgc aucuaccgca     2100

ugaucaagcu cggccucggc aucgacgagg acgaggucgc cgccgaggag cccaacgccg     2160

ccguccccga cgagaucccc ccccucgagg gcgacgagga cgccucccgc auggaggagg     2220

ucgacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  2849
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt2)

<400>  2849
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcgcg       60

cccucugggu ccucggccuc ugcugcgucc uccucaccuu cggcuccguc cgcgccgacg      120

acgaggucga cgucgacggc accgucgagg aggaccucgg caagucccgc gagggcuccc      180

gcaccgacga cgaggucguc cagcgcgagg aggaggccau ccagcucgac ggccucaacg      240

ccucccagau ccgcgagcuc cgcgagaagu ccgagaaguu cgccuuccag gccgagguca      300

accgcaugau gaagcucauc aucaacuccc ucuacaagaa caaggagauc uuccuccgcg      360

agcucaucuc caacgccucc gacgcccucg acaagauccg ccucaucucc cucaccgacg      420

agaacgcccu cuccggcaac gaggagcuca ccgucaagau caagugcgac aaggagaaga      480

accuccucca cgucaccgac accggcgucg gcaugacccg cgaggagcuc gucaagaacc      540

ucggcaccau cgccaagucc ggcaccuccg aguuccucaa caagaugacc gaggcccagg      600

aggacggcca guccaccucc gagcucaucg gccaguucgg cgucggcuuc uacuccgccu      660

uccucgucgc cgacaagguc aucgucaccu ccaagcacaa caacgacacc cagcacaucu      720

gggaguccga cuccaacgag uucuccguca ucgccgaccc ccgcggcaac acccucggcc      780

gcggcaccac caucacccuc guccucaagg aggaggccuc cgacuaccuc gagcucgaca      840

ccaucaagaa ccucgucaag aaguacuccc aguucaucaa cuuccccauc uacgucuggu      900

ccuccaagac cgagaccguc gaggagccca uggaggagga ggaggccgcc aaggaggaga      960

aggaggaguc cgacgacgag gccgccgucg aggaggagga ggaggagaag aagcccaaga     1020

ccaagaaggu cgagaagacc gucugggacu gggagcucau gaacgacauc aagcccaucu     1080

ggcagcgccc cuccaaggag gucgaggagg acgaguacaa ggccuucuac aaguccuucu     1140

ccaaggaguc cgacgacccc auggccuaca uccacuucac cgccgagggc gaggucaccu     1200

ucaaguccau ccucuucguc cccaccuccg ccccccgcgg ccucuucgac gaguacggcu     1260

ccaagaaguc cgacuacauc aagcucuacg uccgccgcgu cuucaucacc gacgacuucc     1320

acgacaugau gcccaaguac cucaacuucg ucaagggcgu cgucgacucc gacgaccucc     1380

cccucaacgu cucccgcgag acccuccagc agcacaagcu ccucaagguc auccgcaaga     1440

agcucguccg caagacccuc gacaugauca agaagaucgc cgacgacaag uacaacgaca     1500

ccuucuggaa ggaguucggc accaacauca agcucggcgu caucgaggac cacuccaacc     1560

gcacccgccu cgccaagcuc cuccgcuucc aguccuccca ccaccccacc gacaucaccu     1620

cccucgacca guacgucgag cgcaugaagg agaagcagga caagaucuac uucauggccg     1680

gcuccucccg caaggaggcc gaguccuccc ccuucgucga gcgccuccuc aagaagggcu     1740

acgaggucau cuaccucacc gagcccgucg acgaguacug cauccaggcc cuccccgagu     1800

ucgacggcaa gcgcuuccag aacgucgcca aggagggcgu caaguucgac gaguccgaga     1860

agaccaagga gucccgcgag gccgucgaga aggaguucga gccccuccuc aacuggauga     1920

aggacaaggc ccucaaggac aagaucgaga aggccgucgu cucccagcgc cucaccgagu     1980

cccccugcgc ccucgucgcc ucccaguacg gcugguccgg caacauggag cgcaucauga     2040

aggcccaggc cuaccagacc ggcaaggaca ucuccaccaa cuacuacgcc ucccagaaga     2100

agaccuucga gaucaacccc cgccaccccc ucauccgcga caugcuccgc cgcaucaagg     2160

aggacgagga cgacaagacc guccucgacc ucgccgucgu ccucuucgag accgccaccc     2220

uccgcuccgg cuaccuccuc cccgacacca aggccuacgg cgaccgcauc gagcgcaugc     2280

uccgccucuc ccucaacauc gaccccgacg ccaaggucga ggaggagccc gaggaggagc     2340

ccgaggagac cgccgaggac accaccgagg acaccgagca ggacgaggac gaggagaugg     2400

acgucggcac cgacgaggag gaggagaccg ccaaggaguc caccgccgag aaggacgagc     2460

ucugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  2850
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt2)

<400>  2850
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

gcgagcuccg cgcccuccuc cucuggggcc gccgccuccg cccccuccuc cgcgcccccg      120

cccucgccgc cguccccggc ggcaagccca uccucugccc ccgccgcacc accgcccagc      180

ucggcccccg ccgcaacccc gccugguccc uccaggccgg ccgccucuuc uccacccaga      240

ccgccgagga caaggaggag ccccuccacu ccaucaucuc cuccaccgag uccguccagg      300

gcuccaccuc caagcacgag uuccaggccg agaccaagaa gcuccucgac aucgucgccc      360

gcucccucua cuccgagaag gaggucuuca uccgcgagcu caucuccaac gccuccgacg      420

cccucgagaa gcuccgccac aagcucgucu ccgacggcca ggcccucccc gagauggaga      480

uccaccucca gaccaacgcc gagaagggca ccaucaccau ccaggacacc ggcaucggca      540

ugacccagga ggagcucguc uccaaccucg gcaccaucgc ccgcuccggc uccaaggccu      600

uccucgacgc ccuccagaac caggccgagg ccuccuccaa gaucaucggc caguucggcg      660

ucggcuucua cuccgccuuc auggucgccg accgcgucga ggucuacucc cgcuccgccg      720

cccccggcuc ccucggcuac caguggcucu ccgacggcuc cggcgucuuc gagaucgccg      780

aggccuccgg cguccgcacc ggcaccaaga ucaucaucca ccucaagucc gacugcaagg      840

aguucuccuc cgaggcccgc guccgcgacg ucgucaccaa guacuccaac uucgucuccu      900

ucccccucua ccucaacggc cgccgcauga acacccucca ggccaucugg augauggacc      960

ccaaggacgu ccgcgagugg cagcacgagg aguucuaccg cuacgucgcc caggcccacg     1020

acaagccccg cuacacccuc cacuacaaga ccgacgcccc ccucaacauc cgcuccaucu     1080

ucuacguccc cgacaugaag cccuccaugu ucgacgucuc ccgcgagcuc ggcuccuccg     1140

ucgcccucua cucccgcaag guccucaucc agaccaaggc caccgacauc cuccccaagu     1200

ggcuccgcuu cauccgcggc gucgucgacu ccgaggacau cccccucaac cucucccgcg     1260

agcuccucca ggaguccgcc cucauccgca agcuccgcga cguccuccag cagcgccuca     1320

ucaaguucuu caucgaccag uccaagaagg acgccgagaa guacgccaag uucuucgagg     1380

acuacggccu cuucaugcgc gagggcaucg ucaccgccac cgagcaggag gucaaggagg     1440

acaucgccaa gcuccuccgc uacgaguccu ccgcccuccc cuccggccag cucaccuccc     1500

ucuccgagua cgccucccgc augcgcgccg gcacccgcaa caucuacuac cucugcgccc     1560

ccaaccgcca ccucgccgag cacucccccu acuacgaggc caugaagaag aaggacaccg     1620

agguccucuu cugcuucgag caguucgacg agcucacccu ccuccaccuc cgcgaguucg     1680

acaagaagaa gcucaucucc gucgagaccg acaucgucgu cgaccacuac aaggaggaga     1740

aguucgagga ccgcuccccc gccgccgagu gccucuccga gaaggagacc gaggagcuca     1800

uggccuggau gcgcaacguc cucggcuccc gcgucaccaa cgucaagguc acccuccgcc     1860

ucgacaccca ccccgccaug gucaccgucc ucgagauggg cgccgcccgc cacuuccucc     1920

gcaugcagca gcucgccaag acccaggagg agcgcgccca gcuccuccag cccacccucg     1980

agaucaaccc ccgccacgcc cucaucaaga agcucaacca gcuccgcgcc uccgagcccg     2040

gccucgccca gcuccucguc gaccagaucu acgagaacgc caugaucgcc gccggccucg     2100

ucgacgaccc ccgcgccaug gucggccgcc ucaacgagcu ccucgucaag gcccucgagc     2160

gccacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  2851
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt2)

<400>  2851
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

agaucuccuc ccuccccacc cagcucuuca agugcugcuu cugcgacuuc cucaagguca      120

agaugcacac cauguccucc ucccaccucu ucuaccucgc ccucugccuc cucaccuuca      180

ccuccuccgc caccgccggc cccgagaccc ucugcggcgc cgagcucguc gacgcccucc      240

aguucgucug cggcgaccgc ggcuucuacu ucaacaagcc caccggcuac ggcuccuccu      300

cccgccgcgc cccccagacc ggcaucgucg acgagugcug cuuccgcucc ugcgaccucc      360

gccgccucga gauguacugc gccccccuca agcccgccaa guccgcccgc uccguccgcg      420

cccagcgcca caccgacaug cccaagaccc agaaggaggu ccaccucaag aacgccuccc      480

gcggcuccgc cggcaacaag aacuaccgca ugugaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  2852
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt2)

<400>  2852
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

uccccauggg caaguccaug cucguccucc ucaccuuccu cgccuucgcc uccugcugca      120

ucgccgccua ccgccccucc gagacccucu gcggcggcga gcucgucgac acccuccagu      180

ucgucugcgg cgaccgcggc uucuacuucu cccgccccgc cucccgcguc ucccgccgcu      240

cccgcggcau cgucgaggag ugcugcuucc gcuccugcga ccucgcccuc cucgagaccu      300

acugcgccac ccccgccaag uccgagcgcg acgucuccac cccccccacc guccuccccg      360

acaacuuccc ccgcuacccc gucggcaagu ucuuccagua cgacaccugg aagcagucca      420

cccagcgccu ccgccgcggc cuccccgccc uccuccgcgc ccgccgcggc cacguccucg      480

ccaaggagcu cgaggccuuc cgcgaggcca agcgccaccg cccccucauc gcccucccca      540

cccaggaccc cgcccacggc ggcgcccccc ccgagauggc cuccaaccgc aagugaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  2853
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt2)

<400>  2853
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

ccuucuccac cuccgccuuc ggccccgucg ccuucucccu cggccuccuc cucguccucc      120

ccgccgccuu ccccgccccc gucccccccg gcgaggacuc caaggacguc gccgcccccc      180

accgccagcc ccucaccucc uccgagcgca ucgacaagca gauccgcuac auccucgacg      240

gcaucuccgc ccuccgcaag gagaccugca acaaguccaa caugugcgag uccuccaagg      300

aggcccucgc cgagaacaac cucaaccucc ccaagauggc cgagaaggac ggcugcuucc      360

aguccggcuu caacgaggag accugccucg ucaagaucau caccggccuc cucgaguucg      420

aggucuaccu cgaguaccuc cagaaccgcu ucgaguccuc cgaggagcag gcccgcgccg      480

uccagauguc caccaagguc cucauccagu uccuccagaa gaaggccaag aaccucgacg      540

ccaucaccac ccccgacccc accaccaacg ccucccuccu caccaagcuc caggcccaga      600

accaguggcu ccaggacaug accacccacc ucauccuccg cuccuucaag gaguuccucc      660

aguccucccu ccgcgcccuc cgccagaugu gaggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  2854
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt2)

<400>  2854
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

uccucuggcu ccgcggcuuc cuccucgccu ccugcuggau caucguccgc uccuccccca      120

cccccggcuc cgagggccac uccgccgccc ccgacugccc cuccugcgcc cucgccgccc      180

uccccaagga cguccccaac ucccagcccg agauggucga ggccgucaag aagcacaucc      240

ucaacaugcu ccaccucaag aagcgccccg acgucaccca gcccgucccc aaggccgccc      300

uccucaacgc cauccgcaag cuccacgucg gcaaggucgg cgagaacggc uacgucgaga      360

ucgaggacga caucggccgc cgcgccgaga ugaacgagcu cauggagcag accuccgaga      420

ucaucaccuu cgccgagucc ggcaccgccc gcaagacccu ccacuucgag aucuccaagg      480

agggcuccga ccucuccguc gucgagcgcg ccgaggucug gcucuuccuc aaggucccca      540

aggccaaccg cacccgcacc aaggucacca uccgccucuu ccagcagcag aagcaccccc      600

agggcucccu cgacaccggc gaggaggccg aggaggucgg ccucaagggc gagcgcuccg      660

agcuccuccu cuccgagaag gucgucgacg cccgcaaguc caccuggcac gucuuccccg      720

ucuccuccuc cauccagcgc cuccucgacc agggcaaguc cucccucgac guccgcaucg      780

ccugcgagca gugccaggag uccggcgccu cccucguccu ccucggcaag aagaagaaga      840

aggaggagga gggcgagggc aagaagaagg gcggcggcga gggcggcgcc ggcgccgacg      900

aggagaagga gcagucccac cgccccuucc ucaugcucca ggcccgccag uccgaggacc      960

acccccaccg ccgccgccgc cgcggccucg agugcgacgg caaggucaac aucugcugca     1020

agaagcaguu cuucgucucc uucaaggaca ucggcuggaa cgacuggauc aucgcccccu     1080

ccggcuacca cgccaacuac ugcgagggcg agugccccuc ccacaucgcc ggcaccuccg     1140

gcuccucccu cuccuuccac uccaccguca ucaaccacua ccgcaugcgc ggccacuccc     1200

ccuucgccaa ccucaagucc ugcugcgucc ccaccaagcu ccgccccaug uccaugcucu     1260

acuacgacga cggccagaac aucaucaaga aggacaucca gaacaugauc gucgaggagu     1320

gcggcugcuc cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  2855
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt2)

<400>  2855
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacg       60

gccuccccgg ccgcgcccuc ggcgccgccu gccuccuccu ccucgccgcc ggcuggcucg      120

gccccgaggc cuggggcucc cccacccccc cccccacccc cgccgccccc cccccccccc      180

ccccccccgg cucccccggc ggcucccagg acaccugcac cuccugcggc ggcuuccgcc      240

gccccgagga gcucggccgc gucgacggcg acuuccucga ggccgucaag cgccacaucc      300

ucucccgccu ccagaugcgc ggccgcccca acaucaccca cgccgucccc aaggccgcca      360

uggucaccgc ccuccgcaag cuccacgccg gcaagguccg cgaggacggc cgcgucgaga      420

ucccccaccu cgacggccac gccucccccg gcgccgacgg ccaggagcgc gucuccgaga      480

ucaucuccuu cgccgagacc gacggccucg ccuccucccg cguccgccuc uacuucuuca      540

ucuccaacga gggcaaccag aaccucuucg ucguccaggc cucccucugg cucuaccuca      600

agcuccuccc cuacguccuc gagaagggcu cccgccgcaa gguccgcguc aaggucuacu      660

uccaggagca gggccacggc gaccgcugga acauggucga gaagcgcguc gaccucaagc      720

gcuccggcug gcacaccuuc ccccucaccg aggccaucca ggcccucuuc gagcgcggcg      780

agcgccgccu caaccucgac guccagugcg acuccugcca ggagcucgcc gucguccccg      840

ucuucgucga ccccggcgag gagucccacc gccccuucgu cgucguccag gcccgccucg      900

gcgacucccg ccaccgcauc cgcaagcgcg gccucgagug cgacggccgc accaaccucu      960

gcugccgcca gcaguucuuc aucgacuucc gccucaucgg cuggaacgac uggaucaucg     1020

cccccaccgg cuacuacggc aacuacugcg agggcuccug ccccgccuac cucgccggcg     1080

uccccggcuc cgccuccucc uuccacaccg ccgucgucaa ccaguaccgc augcgcggcc     1140

ucaaccccgg caccgucaac uccugcugca uccccaccaa gcucuccacc auguccaugc     1200

ucuacuucga cgacgaguac aacaucguca agcgcgacgu ccccaacaug aucgucgagg     1260

agugcggcug cgccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  2856
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt2)

<400>  2856
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

uccgcguccu ccuccucacc gcccucaccc ucugccacgg cuucaaccuc gacaccgaga      120

acgccaugac cuuccaggag aacgcccgcg gcuucggcca guccgucguc cagcuccagg      180

gcucccgcgu cgucgucggc gccccccagg agaucgucgc cgccaaccag cgcggcuccc      240

ucuaccagug cgacuacucc accggcuccu gcgagcccau ccgccuccag guccccgucg      300

aggccgucaa caugucccuc ggccucuccc ucgccgccac caccuccccc ccccagcucc      360

ucgccugcgg ccccaccguc caccagaccu gcuccgagaa caccuacguc aagggccucu      420

gcuuccucuu cggcuccaac cuccgccagc agccccagaa guuccccgag gcccuccgcg      480

gcugccccca ggaggacucc gacaucgccu uccucaucga cggcuccggc uccaucaucc      540

cccacgacuu ccgccgcaug aaggaguucg ucuccaccgu cauggagcag cucaagaagu      600

ccaagacccu cuucucccuc augcaguacu ccgaggaguu ccgcauccac uucaccuuca      660

aggaguucca gaacaacccc aacccccgcu cccucgucaa gcccaucacc cagcuccucg      720

gccgcaccca caccgccacc ggcauccgca aggucguccg cgagcucuuc aacaucacca      780

acggcgcccg caagaacgcc uucaagaucc ucgucgucau caccgacggc gagaaguucg      840

gcgacccccu cggcuacgag gacgucaucc ccgaggccga ccgcgagggc gucauccgcu      900

acgucaucgg cgucggcgac gccuuccgcu ccgagaaguc ccgccaggag cucaacacca      960

ucgccuccaa gcccccccgc gaccacgucu uccaggucaa caacuucgag gcccucaaga     1020

ccauccagaa ccagcuccgc gagaagaucu ucgccaucga gggcacccag accggcuccu     1080

ccuccuccuu cgagcacgag augucccagg agggcuucuc cgccgccauc accuccaacg     1140

gcccccuccu cuccaccguc ggcuccuacg acugggccgg cggcgucuuc cucuacaccu     1200

ccaaggagaa guccaccuuc aucaacauga cccgcgucga cuccgacaug aacgacgccu     1260

accucggcua cgccgccgcc aucauccucc gcaaccgcgu ccagucccuc guccucggcg     1320

ccccccgcua ccagcacauc ggccucgucg ccauguuccg ccagaacacc ggcauguggg     1380

aguccaacgc caacgucaag ggcacccaga ucggcgccua cuucggcgcc ucccucugcu     1440

ccgucgacgu cgacuccaac ggcuccaccg accucguccu caucggcgcc ccccacuacu     1500

acgagcagac ccgcggcggc caggucuccg ucugcccccu cccccgcggc cgcgcccgcu     1560

ggcagugcga cgccguccuc uacggcgagc agggccagcc cuggggccgc uucggcgccg     1620

cccucaccgu ccucggcgac gucaacggcg acaagcucac cgacgucgcc aucggcgccc     1680

ccggcgagga ggacaaccgc ggcgccgucu accucuucca cggcaccucc ggcuccggca     1740

ucucccccuc ccacucccag cgcaucgccg gcuccaagcu cuccccccgc cuccaguacu     1800

ucggccaguc ccucuccggc ggccaggacc ucaccaugga cggccucguc gaccucaccg     1860

ucggcgccca gggccacguc cuccuccucc gcucccagcc cguccuccgc gucaaggcca     1920

ucauggaguu caacccccgc gaggucgccc gcaacgucuu cgagugcaac gaccaggucg     1980

ucaagggcaa ggaggccggc gagguccgcg ucugccucca cguccagaag uccacccgcg     2040

accgccuccg cgagggccag auccaguccg ucgucaccua cgaccucgcc cucgacuccg     2100

gccgccccca cucccgcgcc gucuucaacg agaccaagaa cuccacccgc cgccagaccc     2160

agguccucgg ccucacccag accugcgaga cccucaagcu ccagcucccc aacugcaucg     2220

aggaccccgu cucccccauc guccuccgcc ucaacuucuc ccucgucggc accccccucu     2280

ccgccuucgg caaccuccgc cccguccucg ccgaggacgc ccagcgccuc uucaccgccc     2340

ucuuccccuu cgagaagaac ugcggcaacg acaacaucug ccaggacgac cucuccauca     2400

ccuucuccuu caugucccuc gacugccucg ucgucggcgg cccccgcgag uucaacguca     2460

ccgucaccgu ccgcaacgac ggcgaggacu ccuaccgcac ccaggucacc uucuucuucc     2520

cccucgaccu cuccuaccgc aaggucucca cccuccagaa ccagcgcucc cagcgcuccu     2580

ggcgccucgc cugcgagucc gccuccucca ccgaggucuc cggcgcccuc aaguccaccu     2640

ccugcuccau caaccacccc aucuuccccg agaacuccga ggucaccuuc aacaucaccu     2700

ucgacgucga cuccaaggcc ucccucggca acaagcuccu ccucaaggcc aacgucaccu     2760

ccgagaacaa caugccccgc accaacaaga ccgaguucca gcucgagcuc cccgucaagu     2820

acgccgucua cauggucguc accucccacg gcgucuccac caaguaccuc aacuucaccg     2880

ccuccgagaa caccucccgc gucaugcagc accaguacca ggucuccaac cucggccagc     2940

gcucccuccc caucucccuc gucuuccucg uccccguccg ccucaaccag accgucaucu     3000

gggaccgccc ccaggucacc uucuccgaga accucuccuc caccugccac accaaggagc     3060

gccuccccuc ccacuccgac uuccucgccg agcuccgcaa ggcccccguc gucaacugcu     3120

ccaucgccgu cugccagcgc auccagugcg acauccccuu cuucggcauc caggaggagu     3180

ucaacgccac ccucaagggc aaccucuccu ucgacuggua caucaagacc ucccacaacc     3240

accuccucau cgucuccacc gccgagaucc ucuucaacga cuccgucuuc acccuccucc     3300

ccggccaggg cgccuucguc cgcucccaga ccgagaccaa ggucgagccc uucgaggucc     3360

ccaacccccu cccccucauc gucggcuccu ccgucggcgg ccuccuccuc cucgcccuca     3420

ucaccgccgc ccucuacaag cucggcuucu ucaagcgcca guacaaggac augauguccg     3480

agggcggccc ccccggcgcc gagccccagu gaggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  2857
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt2)

<400>  2857
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguucu       60

cccucaagac ccuccccuuc cuccuccucc uccacgucca gaucuccaag gccuuccccg      120

ucuccuccaa ggagaagaac accaagaccg uccaggacua ccucgagaag uucuaccagc      180

uccccuccaa ccaguaccag uccacccgca agaacggcac caacgucauc gucgagaagc      240

ucaaggagau gcagcgcuuc uucggccuca acgucaccgg caagcccaac gaggagaccc      300

ucgacaugau gaagaagccc cgcugcggcg uccccgacuc cggcggcuuc augcucaccc      360

ccggcaaccc caagugggag cgcaccaacc ucaccuaccg cauccgcaac uacacccccc      420

agcucuccga ggccgagguc gagcgcgcca ucaaggacgc cuucgagcuc ugguccgucg      480

ccuccccccu caucuucacc cgcaucuccc agggcgaggc cgacaucaac aucgccuucu      540

accagcgcga ccacggcgac aacucccccu ucgacggccc caacggcauc cucgcccacg      600

ccuuccagcc cggccagggc aucggcggcg acgcccacuu cgacgccgag gagaccugga      660

ccaacaccuc cgccaacuac aaccucuucc ucgucgccgc ccacgaguuc ggccacuccc      720

ucggccucgc ccacuccucc gaccccggcg cccucaugua ccccaacuac gccuuccgcg      780

agaccuccaa cuacucccuc ccccaggacg acaucgacgg cauccaggcc aucuacggcc      840

ucuccuccaa ccccauccag cccaccggcc ccuccacccc caagcccugc gaccccuccc      900

ucaccuucga cgccaucacc acccuccgcg gcgagauccu cuucuucaag gaccgcuacu      960

ucuggcgccg ccacccccag cuccagcgcg ucgagaugaa cuucaucucc cucuucuggc     1020

ccucccuccc caccggcauc caggccgccu acgaggacuu cgaccgcgac cucaucuucc     1080

ucuucaaggg caaccaguac ugggcccucu ccggcuacga cauccuccag ggcuacccca     1140

aggacaucuc caacuacggc uuccccuccu ccguccaggc caucgacgcc gccgucuucu     1200

accgcuccaa gaccuacuuc uucgucaacg accaguucug gcgcuacgac aaccagcgcc     1260

aguucaugga gcccggcuac cccaagucca ucuccggcgc cuuccccggc aucgagucca     1320

aggucgacgc cgucuuccag caggagcacu ucuuccacgu cuucuccggc ccccgcuacu     1380

acgccuucga ccucaucgcc cagcgcguca cccgcgucgc ccgcggcaac aaguggcuca     1440

acugccgcua cggcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  2858
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt2)

<400>  2858
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccc       60

ucuggcagcc ccucguccuc guccuccucg uccucggcug cugcuucgcc gccccccgcc      120

agcgccaguc cacccucguc cucuuccccg gcgaccuccg caccaaccuc accgaccgcc      180

agcucgccga ggaguaccuc uaccgcuacg gcuacacccg cgucgccgag augcgcggcg      240

aguccaaguc ccucggcccc gcccuccucc uccuccagaa gcagcucucc cuccccgaga      300

ccggcgagcu cgacuccgcc acccucaagg ccaugcgcac cccccgcugc ggcguccccg      360

accucggccg cuuccagacc uucgagggcg accucaagug gcaccaccac aacaucaccu      420

acuggaucca gaacuacucc gaggaccucc cccgcgccgu caucgacgac gccuucgccc      480

gcgccuucgc ccucuggucc gccgucaccc cccucaccuu cacccgcguc uacucccgcg      540

acgccgacau cgucauccag uucggcgucg ccgagcacgg cgacggcuac cccuucgacg      600

gcaaggacgg ccuccucgcc cacgccuucc cccccggccc cggcauccag ggcgacgccc      660

acuucgacga cgacgagcuc uggucccucg gcaagggcgu cgucgucccc acccgcuucg      720

gcaacgccga cggcgccgcc ugccacuucc ccuucaucuu cgagggccgc uccuacuccg      780

ccugcaccac cgacggccgc uccgacggcc uccccuggug cuccaccacc gccaacuacg      840

acaccgacga ccgcuucggc uucugccccu ccgagcgccu cuacacccag gacggcaacg      900

ccgacggcaa gcccugccag uuccccuuca ucuuccaggg ccaguccuac uccgccugca      960

ccaccgacgg ccgcuccgac ggcuaccgcu ggugcgccac caccgccaac uacgaccgcg     1020

acaagcucuu cggcuucugc cccacccgcg ccgacuccac cgucaugggc ggcaacuccg     1080

ccggcgagcu cugcgucuuc cccuucaccu uccucggcaa ggaguacucc accugcaccu     1140

ccgagggccg cggcgacggc cgccucuggu gcgccaccac cuccaacuuc gacuccgaca     1200

agaagugggg cuucugcccc gaccagggcu acucccucuu ccucgucgcc gcccacgagu     1260

ucggccacgc ccucggccuc gaccacuccu ccguccccga ggcccucaug uaccccaugu     1320

accgcuucac cgagggcccc ccccuccaca aggacgacgu caacggcauc cgccaccucu     1380

acggcccccg ccccgagccc gagccccgcc cccccaccac caccaccccc cagcccaccg     1440

ccccccccac cgucugcccc accggccccc ccaccgucca ccccuccgag cgccccaccg     1500

ccggccccac cggccccccc uccgccggcc ccaccggccc ccccaccgcc ggccccucca     1560

ccgccaccac cgucccccuc ucccccgucg acgacgccug caacgucaac aucuucgacg     1620

ccaucgccga gaucggcaac cagcucuacc ucuucaagga cggcaaguac uggcgcuucu     1680

ccgagggccg cggcucccgc ccccagggcc ccuuccucau cgccgacaag uggcccgccc     1740

ucccccgcaa gcucgacucc gucuucgagg agcgccucuc caagaagcuc uucuucuucu     1800

ccggccgcca ggucuggguc uacaccggcg ccuccguccu cggcccccgc cgccucgaca     1860

agcucggccu cggcgccgac gucgcccagg ucaccggcgc ccuccgcucc ggccgcggca     1920

agaugcuccu cuucuccggc cgccgccucu ggcgcuucga cgucaaggcc cagauggucg     1980

acccccgcuc cgccuccgag gucgaccgca uguuccccgg cgucccccuc gacacccacg     2040

acgucuucca guaccgcgag aaggccuacu ucugccagga ccgcuucuac uggcgcgucu     2100

ccucccgcuc cgagcucaac caggucgacc aggucggcua cgucaccuac gacauccucc     2160

agugccccga ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  2859
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt2)

<400>  2859
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ccggcguccu cgccgccuuc cucuuccucu ccuggaccca cugccgcgcc cucccccucc      120

ccuccggcgg cgacgaggac gaccucuccg aggaggaccu ccaguucgcc gagcgcuacc      180

uccgcuccua cuaccacccc accaaccucg ccggcauccu caaggagaac gccgccuccu      240

ccaugaccga gcgccuccgc gagaugcagu ccuucuucgg ccucgagguc accggcaagc      300

ucgacgacaa cacccucgac gucaugaaga agccccgcug cggcgucccc gacgucggcg      360

aguacaacgu cuucccccgc acccucaagu gguccaagau gaaccucacc uaccgcaucg      420

ucaacuacac ccccgacaug acccacuccg aggucgagaa ggccuucaag aaggccuuca      480

aggucugguc cgacgucacc ccccucaacu ucacccgccu ccacgacggc aucgccgaca      540

ucaugaucuc cuucggcauc aaggagcacg gcgacuucua ccccuucgac ggccccuccg      600

gccuccucgc ccacgccuuc ccccccggcc ccaacuacgg cggcgacgcc cacuucgacg      660

acgacgagac cuggaccucc uccuccaagg gcuacaaccu cuuccucguc gccgcccacg      720

aguucggcca cucccucggc cucgaccacu ccaaggaccc cggcgcccuc auguucccca      780

ucuacaccua caccggcaag ucccacuuca ugcuccccga cgacgacguc cagggcaucc      840

agucccucua cggccccggc gacgaggacc ccaaccccaa gcaccccaag acccccgaca      900

agugcgaccc cucccucucc cucgacgcca ucaccucccu ccgcggcgag accaugaucu      960

ucaaggaccg cuucuucugg cgccuccacc cccagcaggu cgacgccgag cucuuccuca     1020

ccaaguccuu cuggcccgag cuccccaacc gcaucgacgc cgccuacgag caccccuccc     1080

acgaccucau cuucaucuuc cgcggccgca aguucugggc ccucaacggc uacgacaucc     1140

ucgagggcua ccccaagaag aucuccgagc ucggccuccc caaggagguc aagaagaucu     1200

ccgccgccgu ccacuucgag gacaccggca agacccuccu cuucuccggc aaccaggucu     1260

ggcgcuacga cgacaccaac cacaucaugg acaaggacua cccccgccuc aucgaggagg     1320

acuuccccgg caucggcgac aaggucgacg ccgucuacga gaagaacggc uacaucuacu     1380

ucuucaacgg ccccauccag uucgaguacu ccaucugguc caaccgcauc guccgcguca     1440

ugcccgccaa cuccauccuc uggugcugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  2860
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt2)

<400>  2860
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

cccccaacac caccgaggac uacgacacca ccaccgaguu cgacuacggc gacgccaccc      120

ccugccagaa ggucaacgag cgcgccuucg gcgcccagcu ccuccccccc cucuacuccc      180

ucgucuucgu caucggccuc gucggcaaca uccucgucgu ccucguccuc guccaguaca      240

agcgccucaa gaacaugacc uccaucuacc uccucaaccu cgccaucucc gaccuccucu      300

uccucuucac ccuccccuuc uggaucgacu acaagcucaa ggacgacugg gucuucggcg      360

acgccaugug caagauccuc uccggcuucu acuacaccgg ccucuacucc gagaucuucu      420

ucaucauccu ccucaccauc gaccgcuacc ucgccaucgu ccacgccguc uucgcccucc      480

gcgcccgcac cgucaccuuc ggcgucauca ccuccaucau caucugggcc cucgccaucc      540

ucgccuccau gcccggccuc uacuucucca agacccagug ggaguucacc caccacaccu      600

gcucccucca cuucccccac gagucccucc gcgaguggaa gcucuuccag gcccucaagc      660

ucaaccucuu cggccucguc cucccccucc ucgucaugau caucugcuac accggcauca      720

ucaagauccu ccuccgccgc cccaacgaga agaaguccaa ggccguccgc cucaucuucg      780

ucaucaugau caucuucuuc cucuucugga cccccuacaa ccucaccauc cucaucuccg      840

ucuuccagga cuuccucuuc acccacgagu gcgagcaguc ccgccaccuc gaccucgccg      900

uccaggucac cgaggucauc gccuacaccc acugcugcgu caaccccguc aucuacgccu      960

ucgucggcga gcgcuuccgc aaguaccucc gccagcucuu ccaccgccgc gucgccgucc     1020

accucgucaa guggcucccc uuccucuccg ucgaccgccu cgagcgcguc uccuccaccu     1080

cccccuccac cggcgagcac gagcucuccg ccggcuucug aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  2861
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt2)

<400>  2861
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcgca       60

cccucgccug ccuccuccuc cucggcugcg gcuaccucgc ccacguccuc gccgaggagg      120

ccgagauccc ccgcgagguc aucgagcgcc ucgcccgcuc ccagauccac uccauccgcg      180

accuccagcg ccuccucgag aucgacuccg ucggcuccga ggacucccuc gacaccuccc      240

uccgcgccca cggcguccac gccaccaagc acguccccga gaagcgcccc cuccccaucc      300

gccgcaagcg cuccaucgag gaggccgucc ccgccgucug caagacccgc accgucaucu      360

acgagauccc ccgcucccag gucgacccca ccuccgccaa cuuccucauc uggccccccu      420

gcgucgaggu caagcgcugc accggcugcu gcaacaccuc cuccgucaag ugccagcccu      480

cccgcgucca ccaccgcucc gucaaggucg ccaaggucga guacguccgc aagaagccca      540

agcucaagga gguccagguc cgccucgagg agcaccucga gugcgccugc gccaccaccu      600

cccucaaccc cgacuaccgc gaggaggaca ccggccgccc ccgcgagucc ggcaagaagc      660

gcaagcgcaa gcgccucaag cccaccugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  2862
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt2)

<400>  2862
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacc       60

gcugcugggc ccucuuccuc ucccucugcu gcuaccuccg ccucgucucc gccgagggcg      120

accccauccc cgaggagcuc uacgagaugc ucuccgacca cuccauccgc uccuucgacg      180

accuccagcg ccuccuccac ggcgaccccg gcgaggagga cggcgccgag cucgaccuca      240

acaugacccg cucccacucc ggcggcgagc ucgagucccu cgcccgcggc cgccgcuccc      300

ucggcucccu caccaucgcc gagcccgcca ugaucgccga gugcaagacc cgcaccgagg      360

ucuucgagau cucccgccgc cucaucgacc gcaccaacgc caacuuccuc gucuggcccc      420

ccugcgucga gguccagcgc ugcuccggcu gcugcaacaa ccgcaacguc cagugccgcc      480

ccacccaggu ccagcuccgc cccguccagg uccgcaagau cgagaucguc cgcaagaagc      540

ccaucuucaa gaaggccacc gucacccucg aggaccaccu cgccugcaag ugcgagaccg      600

ucgccgccgc ccgccccguc acccgcuccc ccggcggcuc ccaggagcag cgcgccaaga      660

ccccccagac ccgcgucacc auccgcaccg uccgcguccg ccgccccccc aagggcaagc      720

accgcaaguu caagcacacc cacgacaaga ccgcccucaa ggagacccuc ggcgccugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  2863
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt2)

<400>  2863
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccc       60

ucuucggccu ccuccuccuc accuccgccc ucgccggcca gcgccagggc acccaggccg      120

aguccaaccu cuccuccaag uuccaguucu ccuccaacaa ggagcagaac ggcguccagg      180

acccccagca cgagcgcauc aucaccgucu ccaccaacgg cuccauccac uccccccgcu      240

ucccccacac cuacccccgc aacaccgucc ucgucuggcg ccucgucgcc gucgaggaga      300

acgucuggau ccagcucacc uucgacgagc gcuucggccu cgaggacccc gaggacgaca      360

ucugcaagua cgacuucguc gaggucgagg agcccuccga cggcaccauc cucggccgcu      420

ggugcggcuc cggcaccguc cccggcaagc agaucuccaa gggcaaccag auccgcaucc      480

gcuucgucuc cgacgaguac uuccccuccg agcccggcuu cugcauccac uacaacaucg      540

ucaugcccca guucaccgag gccgucuccc ccuccguccu cccccccucc gcccuccccc      600

ucgaccuccu caacaacgcc aucaccgccu ucuccacccu cgaggaccuc auccgcuacc      660

ucgagcccga gcgcuggcag cucgaccucg aggaccucua ccgccccacc uggcagcucc      720

ucggcaaggc cuucgucuuc ggccgcaagu cccgcgucgu cgaccucaac cuccucaccg      780

aggagguccg ccucuacucc ugcacccccc gcaacuucuc cgucuccauc cgcgaggagc      840

ucaagcgcac cgacaccauc uucuggcccg gcugccuccu cgucaagcgc ugcggcggca      900

acugcgccug cugccuccac aacugcaacg agugccagug cguccccucc aaggucacca      960

agaaguacca cgagguccuc cagcuccgcc ccaagaccgg cguccgcggc cuccacaagu     1020

cccucaccga cgucgcccuc gagcaccacg aggagugcga cugcgucugc cgcggcucca     1080

ccggcggcug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  2864
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt2)

<400>  2864
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

gccucaucuu cgucuacacc cucaucugcg ccaacuucug cuccugccgc gacaccuccg      120

ccacccccca guccgccucc aucaaggccc uccgcaacgc caaccuccgc cgcgacgacc      180

ucuaccgccg cgacgagacc auccagguca agggcaacgg cuacguccag uccccccgcu      240

uccccaacuc cuacccccgc aaccuccucc ucaccuggcg ccuccacucc caggagaaca      300

cccgcaucca gcucgucuuc gacaaccagu ucggccucga ggaggccgag aacgacaucu      360

gccgcuacga cuucgucgag gucgaggaca ucuccgagac cuccaccauc auccgcggcc      420

gcuggugcgg ccacaaggag gucccccccc gcaucaaguc ccgcaccaac cagaucaaga      480

ucaccuucaa guccgacgac uacuucgucg ccaagcccgg cuucaagauc uacuacuccc      540

uccucgagga cuuccagccc gccgccgccu ccgagaccaa cugggagucc gucaccuccu      600

ccaucuccgg cgucuccuac aacucccccu ccgucaccga ccccacccuc aucgccgacg      660

cccucgacaa gaagaucgcc gaguucgaca ccgucgagga ccuccucaag uacuucaacc      720

ccgaguccug gcaggaggac cucgagaaca uguaccucga caccccccgc uaccgcggcc      780

gcuccuacca cgaccgcaag uccaaggucg accucgaccg ccucaacgac gacgccaagc      840

gcuacuccug caccccccgc aacuacuccg ucaacauccg cgaggagcuc aagcucgcca      900

acgucgucuu cuucccccgc ugccuccucg uccagcgcug cggcggcaac ugcggcugcg      960

gcaccgucaa cuggcgcucc ugcaccugca acuccggcaa gaccgucaag aaguaccacg     1020

agguccucca guucgagccc ggccacauca agcgccgcgg ccgcgccaag accauggccc     1080

ucgucgacau ccagcucgac caccacgagc gcugcgacug caucugcucc ucccgccccc     1140

cccgcugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  2865
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt2)

<400>  2865
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguca       60

cccacuccaa guuccccgcc gccggcaugu cccgcccccu cgacaccucc cuccgccuca      120

agaccuucuc cuccaagucc gaguaccagc ucgucgucaa cgccguccgc aagcuccagg      180

aguccggcuu cuacuggucc gccgucaccg gcggcgaggc caaccuccuc cucuccgccg      240

agcccgccgg caccuuccuc auccgcgacu ccuccgacca gcgccacuuc uucacccucu      300

ccgucaagac ccaguccggc accaagaacc uccgcaucca gugcgagggc ggcuccuucu      360

cccuccaguc cgacccccgc uccacccagc ccgucccccg cuucgacugc guccucaagc      420

ucguccacca cuacaugccc ccccccggcg cccccuccuu ccccuccccc cccaccgagc      480

ccuccuccga gguccccgag cagcccuccg cccagccccu ccccggcucc cccccccgcc      540

gcgccuacua caucuacucc ggcggcgaga agaucccccu cguccucucc cgcccccucu      600

ccuccaacgu cgccacccuc cagcaccucu gccgcaagac cgucaacggc caccucgacu      660

ccuacgagaa ggucacccag cuccccggcc ccauccgcga guuccucgac caguacgacg      720

ccccccucug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  2866
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt2)

<400>  2866
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucc       60

ccuccgccgg ccagcucgcc cucuucgccc ucggcaucgu ccucgccgcc ugccaggccc      120

ucgagaacuc caccuccccc cucuccgccg acccccccgu cgccgccgcc gucgucuccc      180

acuucaacga cugccccgac ucccacaccc aguucugcuu ccacggcacc ugccgcuucc      240

ucguccagga ggacaagccc gccugcgucu gccacuccgg cuacgucggc gcccgcugcg      300

agcacgccga ccuccucgcc gucgucgccg ccucccagaa gaagcaggcc aucaccgccc      360

ucgucgucgu cuccaucguc gcccucgccg uccucaucau caccugcguc cucauccacu      420

gcugccaggu ccgcaagcac ugcgaguggu gccgcgcccu caucugccgc cacgagaagc      480

ccuccgcccu ccucaagggc cgcaccgccu gcugccacuc cgagaccguc gucugaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  2867
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt2)

<400>  2867
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ccuccggccu ccgccuccuc ccccuccucc ucccccuccu cuggcuccuc guccucaccc      120

ccggccgccc cgccgccggc cucuccaccu gcaagaccau cgacauggag cucgucaagc      180

gcaagcgcau cgaggccauc cgcggccaga uccucuccaa gcuccgccuc gccucccccc      240

ccucccaggg cgaggucccc cccggccccc uccccgaggc cguccucgcc cucuacaacu      300

ccacccgcga ccgcgucgcc ggcgaguccg ccgagcccga gcccgagccc gaggccgacu      360

acuacgccaa ggaggucacc cgcguccuca uggucgagac ccacaacgag aucuacgaca      420

aguucaagca guccacccac uccaucuaca uguucuucaa caccuccgag cuccgcgagg      480

ccguccccga gcccguccuc cucucccgcg ccgagcuccg ccuccuccgc cucaagcuca      540

aggucgagca gcacgucgag cucuaccaga aguacuccaa caacuccugg cgcuaccucu      600

ccaaccgccu ccucgccccc uccgacuccc ccgaguggcu cuccuucgac gucaccggcg      660

ucguccgcca guggcucucc cgcggcggcg agaucgaggg cuuccgccuc uccgcccacu      720

gcuccugcga cucccgcgac aacacccucc aggucgacau caacggcuuc accaccggcc      780

gccgcggcga ccucgccacc auccacggca ugaaccgccc cuuccuccuc cucauggcca      840

ccccccucga gcgcgcccag caccuccagu ccucccgcca ccgccgcgcc cucgacacca      900

acuacugcuu cuccuccacc gagaagaacu gcugcguccg ccagcucuac aucgacuucc      960

gcaaggaccu cggcuggaag uggauccacg agcccaaggg cuaccacgcc aacuucugcc     1020

ucggccccug ccccuacauc uggucccucg acacccagua cuccaagguc cucgcccucu     1080

acaaccagca caaccccggc gccuccgccg cccccugcug cgucccccag gcccucgagc     1140

cccuccccau cgucuacuac gucggccgca agcccaaggu cgagcagcuc uccaacauga     1200

ucguccgcuc cugcaagugc uccugaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  2868
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt2)

<400>  2868
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugcguccu cuccgccuuc cucauccucc accucgucac cgucgcccuc ucccucucca      120

ccugcuccac ccucgacaug gaccaguuca ugcgcaagcg caucgaggcc auccgcggcc      180

agauccucuc caagcucaag cucaccuccc cccccgagga cuaccccgag cccgaggagg      240

ucccccccga ggucaucucc aucuacaacu ccacccgcga ccuccuccag gagaaggccu      300

cccgccgcgc cgccgccugc gagcgcgagc gcuccgacga ggaguacuac gccaaggagg      360

ucuacaagau cgacaugccc cccuucuucc ccuccgagaa cgccaucccc cccaccuucu      420

accgccccua cuuccgcauc guccgcuucg acgucuccgc cauggagaag aacgccucca      480

accucgucaa ggccgaguuc cgcgucuucc gccuccagaa ccccaaggcc cgcguccccg      540

agcagcgcau cgagcucuac cagauccuca aguccaagga ccucaccucc cccacccagc      600

gcuacaucga cuccaagguc gucaagaccc gcgccgaggg cgaguggcuc uccuucgacg      660

ucaccgacgc cguccacgag uggcuccacc acaaggaccg caaccucggc uucaagaucu      720

cccuccacug ccccugcugc accuucgucc ccuccaacaa cuacaucauc cccaacaagu      780

ccgaggagcu cgaggcccgc uucgccggca ucgacggcac cuccaccuac accuccggcg      840

accagaagac caucaagucc acccgcaaga agaacuccgg caagaccccc caccuccucc      900

ucaugcuccu ccccuccuac cgccucgagu cccagcagac caaccgccgc aagaagcgcg      960

cccucgacgc cgccuacugc uuccgcaacg uccaggacaa cugcugccuc cgcccccucu     1020

acaucgacuu caagcgcgac cucggcugga aguggaucca cgagcccaag ggcuacaacg     1080

ccaacuucug cgccggcgcc ugccccuacc ucugguccuc cgacacccag cacucccgcg     1140

uccucucccu cuacaacacc aucaaccccg aggccuccgc cucccccugc ugcgucuccc     1200

aggaccucga gccccucacc auccucuacu acaucggcaa gacccccaag aucgagcagc     1260

ucuccaacau gaucgucaag uccugcaagu gcuccugagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  2869
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt2)

<400>  2869
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

ugcaccucca gcgcgcccuc gucguccucg cccuccucaa cuucgccacc gucucccucu      120

cccucuccac cugcaccacc cucgacuucg gccacaucaa gaagaagcgc gucgaggcca      180

uccgcggcca gauccucucc aagcuccgcc ucaccucccc ccccgagccc accgucauga      240

cccacguccc cuaccagguc cucgcccucu acaacuccac ccgcgagcuc cucgaggaga      300

ugcacggcga gcgcgaggag ggcugcaccc aggagaacac cgaguccgag uacuacgcca      360

aggagaucca caaguucgac augauccagg gccucgccga gcacaacgag cucgccgucu      420

gccccaaggg caucaccucc aaggucuucc gcuucaacgu cuccuccguc gagaagaacc      480

gcaccaaccu cuuccgcgcc gaguuccgcg uccuccgcgu ccccaacccc uccuccaagc      540

gcaacgagca gcgcaucgag cucuuccaga uccuccgccc cgacgagcac aucgccaagc      600

agcgcuacau cggcggcaag aaccucccca cccgcggcac cgccgagugg cucuccuucg      660

acgucaccga caccguccgc gaguggcucc uccgccgcga guccaaccuc ggccucgaga      720

ucuccaucca cugccccugc cacaccuucc agcccaacgg cgacauccuc gagaacaucc      780

acgaggucau ggagaucaag uucaagggcg ucgacaacga ggacgaccac ggccgcggcg      840

accucggccg ccucaagaag cagaaggacc accacaaccc ccaccucauc cucaugauga      900

ucccccccca ccgccucgac aaccccggcc agggcggcca gcgcaagaag cgcgcccucg      960

acaccaacua cugcuuccgc aaccucgagg agaacugcug cguccgcccc cucuacaucg     1020

acuuccgcca ggaccucggc uggaaguggg uccacgagcc caagggcuac uacgccaacu     1080

ucugcuccgg ccccugcccc uaccuccgcu ccgccgacac cacccacucc accguccucg     1140

gccucuacaa cacccucaac cccgaggccu ccgccucccc cugcugcguc ccccaggacc     1200

ucgagccccu caccauccuc uacuacgucg gccgcacccc caaggucgag cagcucucca     1260

acauggucgu caaguccugc aagugcuccu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2870
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt2)

<400>  2870
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ccgucgccgu cugggccgcc cucgccgucg gccucgagcu cugggccgcc gcccacgccc      120

uccccgccca ggucgccuuc acccccuacg cccccgagcc cggcuccacc ugccgccucc      180

gcgaguacua cgaccagacc gcccagaugu gcugcuccaa gugcuccccc ggccagcacg      240

ccaaggucuu cugcaccaag accuccgaca ccgucugcga cuccugcgag gacuccaccu      300

acacccagcu cuggaacugg guccccgagu gccucuccug cggcucccgc ugcuccuccg      360

accaggucga gacccaggcc ugcacccgcg agcagaaccg caucugcacc ugccgccccg      420

gcugguacug cgcccucucc aagcaggagg gcugccgccu cugcgccccc cuccgcaagu      480

gccgccccgg cuucggcguc gcccgccccg gcaccgagac cuccgacguc gucugcaagc      540

ccugcgcccc cggcaccuuc uccaacacca ccuccuccac cgacaucugc cgcccccacc      600

agaucugcaa cgucgucgcc auccccggca acgccuccau ggacgccguc ugcaccucca      660

ccucccccac ccgcuccaug gcccccggcg ccguccaccu cccccagccc gucuccaccc      720

gcucccagca cacccagccc acccccgagc ccuccaccgc ccccuccacc uccuuccucc      780

uccccauggg ccccuccccc cccgccgagg gcuccaccgg cgacuucgcc cuccccgucg      840

gccucaucgu cggcgucacc gcccucggcc uccucaucau cggcgucguc aacugcguca      900

ucaugaccca ggucaagaag aagccccucu gccuccagcg cgaggccaag gucccccacc      960

uccccgccga caaggcccgc ggcacccagg gccccgagca gcagcaccuc cucaucaccg     1020

cccccuccuc cuccuccucc ucccucgagu ccuccgccuc cgcccucgac cgccgcgccc     1080

ccacccgcaa ccagccccag gcccccggcg ucgaggccuc cggcgccggc gaggcccgcg     1140

ccuccaccgg cuccuccgac uccucccccg gcggccacgg cacccagguc aacgucaccu     1200

gcaucgucaa cgucugcucc uccuccgacc acuccuccca gugcuccucc caggccuccu     1260

ccaccauggg cgacaccgac uccucccccu ccgagucccc caaggacgag cagguccccu     1320

ucuccaagga ggagugcgcc uuccgcuccc agcucgagac ccccgagacc cuccucggcu     1380

ccaccgagga gaagccccuc ccccucggcg uccccgacgc cggcaugaag cccuccugag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  2871
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt2)

<400>  2871
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

ucaugcgccu cuuccccugc uuccuccagc uccucgccgg ccucgcccuc cccgccgucc      120

ccccccagca gugggcccuc uccgccggca acggcuccuc cgaggucgag gucguccccu      180

uccaggaggu cuggggccgc uccuacugcc gcgcccucga gcgccucguc gacgucgucu      240

ccgaguaccc cuccgagguc gagcacaugu ucucccccuc cugcgucucc cuccuccgcu      300

gcaccggcug cugcggcgac gagaaccucc acugcguccc cgucgagacc gccaacguca      360

ccaugcagcu ccucaagauc cgcuccggcg accgccccuc cuacgucgag cucaccuucu      420

cccagcacgu ccgcugcgag ugccgccccc uccgcgagaa gaugaagccc gagcgccgcc      480

gccccaaggg ccgcggcaag cgccgccgcg agaagcagcg ccccaccgac ugccaccucu      540

gcggcgacgc cgucccccgc cgcugaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  2872
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt2)

<400>  2872
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

accgccagac cgacaccgcc cccucccccu ccuaccaccu ccuccccggc cgccgccgca      120

ccgucgacgc cgccgccucc cgcggccagg gccccgagcc cgcccccggc ggcggcgucg      180

agggcgucgg cgcccgcggc gucgcccuca agcucuucgu ccagcuccuc ggcugcuccc      240

gcuucggcgg cgccgucguc cgcgccggcg aggccgagcc cuccggcgcc gcccgcuccg      300

ccuccuccgg ccgcgaggag ccccagcccg aggagggcga ggaggaggag gagaaggagg      360

aggagcgcgg cccccagugg cgccucggcg cccgcaagcc cggcuccugg accggcgagg      420

ccgccgucug cgccgacucc gcccccgccg cccgcgcccc ccaggcccuc gcccgcgccu      480

ccggccgcgg cggccgcguc gcccgccgcg gcgccgagga guccggcccc ccccacuccc      540

ccucccgccg cggcuccgcc ucccgcgccg gccccggccg cgccuccgag accaugaacu      600

uccuccucuc cuggguccac uggucccucg cccuccuccu cuaccuccac cacgccaagu      660

ggucccaggc cgcccccaug gccgagggcg gcggccagaa ccaccacgag gucgucaagu      720

ucauggacgu cuaccagcgc uccuacugcc accccaucga gacccucguc gacaucuucc      780

aggaguaccc cgacgagauc gaguacaucu ucaagcccuc cugcgucccc cucaugcgcu      840

gcggcggcug cugcaacgac gagggccucg agugcguccc caccgaggag uccaacauca      900

ccaugcagau caugcgcauc aagccccacc agggccagca caucggcgag auguccuucc      960

uccagcacaa caagugcgag ugccgcccca agaaggaccg cgcccgccag gagaagaagu     1020

ccguccgcgg caagggcaag ggccagaagc gcaagcgcaa gaagucccgc uacaaguccu     1080

gguccgucua cgucggcgcc cgcugcugcc ucaugcccug gucccucccc ggcccccacc     1140

ccugcggccc cugcuccgag cgccgcaagc accucuucgu ccaggacccc cagaccugca     1200

agugcuccug caagaacacc gacucccgcu gcaaggcccg ccagcucgag cucaacgagc     1260

gcaccugccg cugcgacaag ccccgccgcu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2873
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt2)

<400>  2873
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuccucuc cuggguccac uggucccucg cccuccuccu cuaccuccac cacgccaagu      120

ggucccaggc cgcccccaug gccgagggcg gcggccagaa ccaccacgag gucgucaagu      180

ucauggacgu cuaccagcgc uccuacugcc accccaucga gacccucguc gacaucuucc      240

aggaguaccc cgacgagauc gaguacaucu ucaagcccuc cugcgucccc cucaugcgcu      300

gcggcggcug cugcaacgac gagggccucg agugcguccc caccgaggag uccaacauca      360

ccaugcagau caugcgcauc aagccccacc agggccagca caucggcgag auguccuucc      420

uccagcacaa caagugcgag ugccgcccca agaaggaccg cgcccgccag gagaagaagu      480

ccguccgcgg caagggcaag ggccagaagc gcaagcgcaa gaagucccgc uacaaguccu      540

gguccgucua cgucggcgcc cgcugcugcc ucaugcccug gucccucccc ggcccccacc      600

ccugcggccc cugcuccgag cgccgcaagc accucuucgu ccaggacccc cagaccugca      660

agugcuccug caagaacacc gacucccgcu gcaaggcccg ccagcucgag cucaacgagc      720

gcaccugccg cugcgacaag ccccgccgcu gaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  2874
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt2)

<400>  2874
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccc       60

cccuccuccg ccgccuccuc cucgccgccc uccuccagcu cgcccccgcc caggcccccg      120

ucucccagcc cgacgccccc ggccaccagc gcaaggucgu cuccuggauc gacgucuaca      180

cccgcgccac cugccagccc cgcgaggucg ucgucccccu caccgucgag cucaugggca      240

ccgucgccaa gcagcucguc cccuccugcg ucaccgucca gcgcugcggc ggcugcugcc      300

ccgacgacgg ccucgagugc guccccaccg gccagcacca gguccgcaug cagauccuca      360

ugauccgcua ccccuccucc cagcucggcg agaugucccu cgaggagcac ucccagugcg      420

agugccgccc caagaagaag gacuccgccg ucaagcccga ccgcgccgcc accccccacc      480

accgccccca gccccgcucc guccccggcu gggacuccgc ccccggcgcc cccucccccg      540

ccgacaucac ccaccccacc cccgcccccg gccccuccgc ccacgccgcc cccuccacca      600

ccuccgcccu cacccccggc cccgccgccg ccgccgccga cgccgccgcc uccuccgucg      660

ccaagggcgg cgccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  2875
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt2)

<400>  2875
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

uccucggcuu cuucuccguc gccugcuccc uccucgccgc cgcccuccuc cccggccccc      120

gcgaggcccc cgccgccgcc gccgccuucg aguccggccu cgaccucucc gacgccgagc      180

ccgacgccgg cgaggccacc gccuacgccu ccaaggaccu cgaggagcag cuccgcuccg      240

ucuccuccgu cgacgagcuc augaccgucc ucuaccccga guacuggaag auguacaagu      300

gccagcuccg caagggcggc uggcagcaca accgcgagca ggccaaccuc aacucccgca      360

ccgaggagac caucaaguuc gccgccgccc acuacaacac cgagauccuc aaguccaucg      420

acaacgagug gcgcaagacc cagugcaugc cccgcgaggu cugcaucgac gucggcaagg      480

aguucggcgu cgccaccaac accuucuuca agccccccug cgucuccguc uaccgcugcg      540

gcggcugcug caacuccgag ggccuccagu gcaugaacac cuccaccucc uaccucucca      600

agacccucuu cgagaucacc gucccccucu cccagggccc caagcccguc accaucuccu      660

ucgccaacca caccuccugc cgcugcaugu ccaagcucga cgucuaccgc cagguccacu      720

ccaucauccg ccgcucccuc cccgccaccc ucccccagug ccaggccgcc aacaagaccu      780

gccccaccaa cuacaugugg aacaaccaca ucugccgcug ccucgcccag gaggacuuca      840

uguucuccuc cgacgccggc gacgacucca ccgacggcuu ccacgacauc ugcggcccca      900

acaaggagcu cgacgaggag accugccagu gcgucugccg cgccggccuc cgccccgccu      960

ccugcggccc ccacaaggag cucgaccgca acuccugcca gugcgucugc aagaacaagc     1020

ucuuccccuc ccagugcggc gccaaccgcg aguucgacga gaacaccugc cagugcgucu     1080

gcaagcgcac cugcccccgc aaccagcccc ucaaccccgg caagugcgcc ugcgagugca     1140

ccgagucccc ccagaagugc cuccucaagg gcaagaaguu ccaccaccag accugcuccu     1200

gcuaccgccg ccccugcacc aaccgccaga aggccugcga gcccggcuuc uccuacuccg     1260

aggaggucug ccgcugcguc cccuccuacu ggaagcgccc ccagaugucc ugaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  2876
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt2)

<400>  2876
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguacc       60

gcgagugggu cgucgucaac gucuucauga ugcucuacgu ccagcucguc cagggcuccu      120

ccaacgagca cggccccguc aagcgcuccu cccaguccac ccucgagcgc uccgagcagc      180

agauccgcgc cgccuccucc cucgaggagc uccuccgcau cacccacucc gaggacugga      240

agcucuggcg cugccgccuc cgccucaagu ccuucaccuc cauggacucc cgcuccgccu      300

cccaccgcuc cacccgcuuc gccgccaccu ucuacgacau cgagacccuc aaggucaucg      360

acgaggagug gcagcgcacc cagugcuccc cccgcgagac cugcgucgag gucgccuccg      420

agcucggcaa guccaccaac accuucuuca agccccccug cgucaacguc uuccgcugcg      480

gcggcugcug caacgaggag ucccucaucu gcaugaacac cuccaccucc uacaucucca      540

agcagcucuu cgagaucucc gucccccuca ccuccguccc cgagcucguc cccgucaagg      600

ucgccaacca caccggcugc aagugccucc ccaccgcccc ccgccacccc uacuccauca      660

uccgccgcuc cauccagauc cccgaggagg accgcugcuc ccacuccaag aagcucugcc      720

ccaucgacau gcucugggac uccaacaagu gcaagugcgu ccuccaggag gagaaccccc      780

ucgccggcac cgaggaccac ucccaccucc aggagcccgc ccucugcggc ccccacauga      840

uguucgacga ggaccgcugc gagugcgucu gcaagacccc cugccccaag gaccucaucc      900

agcaccccaa gaacugcucc ugcuucgagu gcaaggaguc ccucgagacc ugcugccaga      960

agcacaagcu cuuccacccc gacaccugcu ccugcgagga ccgcugcccc uuccacaccc     1020

gccccugcgc cuccggcaag accgccugcg ccaagcacug ccgcuucccc aaggagaagc     1080

gcgccgccca gggcccccac ucccgcaaga accccugagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  2877
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt3)

<400>  2877
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcgaugagac cggcuucgaa cacuccgggc uguggguguc uguccucgcc ggacuucugu      120

ugggugcuug ccaggcacau cccaucccug acucaagucc auuacugcaa uuuggcgggc      180

agguuagaca gagguaccua uauacagaug acgcccagca aacugaggcg caccucgaaa      240

uucgggagga uggaacggug ggcggugcug ccgaccagag cccggaaucc cugcuucagc      300

ugaaggcauu gaaacccggg guaauacaga uccucggagu gaagaccucu cgcuuccugu      360

gucaacgacc ugauggcgcc cuguacggcu cgcuccauuu ugacccagag gcuugcucau      420

uccgugaguu acugcuugaa gauggguaua acgucuacca gagcgaggca cacggauugc      480

cccugcaucu accugguaau aaaaguccac acagagaccc cgccccuagg ggcccagcuc      540

gguuucuccc gcugcccggg cuuccuccag cccugcccga accuccagga auuuuggcgc      600

cccagccgcc ugaugugggc uccucugacc cccucagcau gguuggucca ucccaggggc      660

gcucaccuag uuaugcaagc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  2878
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt3)

<400>  2878
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuuuccccc ucugcuccuu cuguuguucu ggggcguggu cucccauucu uucccagcca      120

ccuuagagac acaggaacaa gacguugauc uggugcagaa guaccuagag aaauauuaca      180

accucaagaa ugacgggaga cagguagaga aaaggcggaa cucaggaccg guggucgaaa      240

agcugaaaca gaugcaagaa uuuuucgguc uuaaggugac uggcaagccc gaugcugaga      300

cgcugaaagu uaugaagcag ccucgcugcg gggugccaga cgucgcacag uuuguguuga      360

ccgagggaaa uccccgaugg gaacagacac accucacuua ucguaucgag aacuacaccc      420

cugaucugcc aagagccgac guagaucaug cgauugaaaa ggcuuuccaa cuguggagua      480

auguuacacc ccucaccuuu acuaaaguga gcgagggcca ggccgacaua augaucuccu      540

ucgucagggg ugaucaccgg gacaacucuc cuuuugaugg gccaggaggc aauuuagcac      600

augccuucca gccgggcccc gggauuggag gugacgcuca cuuugaugag gacgaacgcu      660

ggacaaacaa uuucagagag uauaaccugc acaggguggc agcccaugaa cuuggccacu      720

cguuggggcu gucacauagc accgacaucg gagcucuaau guacccuagu uauacguuuu      780

ccggcgaugu gcagcucgcc caagacgaua uugacgguau ccaggcgaua uacgggcggu      840

cucagaaucc aguccaaccc aucggaccuc agacuccaaa agcaugugau agcaagcuga      900

ccuucgacgc cauuacaacu auccgcggcg agguuauguu cuuuaaggau cgauucuaca      960

ugagaaccaa ccccuuuuau ccggaagugg agcuuaauuu cauuuccgua uuuuggccuc     1020

agcugcccaa cggcuuggag gcugccuacg aguucgcaga cagggaugaa gugcgguuuu     1080

ucaaagggaa uaaguauugg gcuguccagg gacaaaacgu gcuccacggu uacccaaaag     1140

acaucuauuc aaguuuuggc uucccucgua caguuaagca cauagaugcc gcgcugagcg     1200

aagagaacac cgggaaaacg uacuuuuucg uggccaauaa guauuggcgc uacgacgaau     1260

acaaaagauc uauggacccc ggauauccaa agaugauugc acaugauuuu cccggcaucg     1320

gucacaaggu cgacgcugug uucaugaaag auggguucuu uuacuucuuu cauggcacua     1380

ggcaguauaa guucgacccu aaaacaaagc ggauuuuaac ccugcagaaa gccaacuccu     1440

gguuuaauug ccgaaagaac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  2879
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt3)

<400>  2879
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuuuccccc ucugcuccuu cuguuguucu ggggcguggu cucccauucu uucguuuuaa      120

ccgaggggaa cccaagaugg gaacagacac accugacuua caggaucgag aauuauacgc      180

cggaccuacc ccgggccgau guggaccaug cuauugaaaa ggcauuucaa cucuggucaa      240

acguaacccc ucugacauuc acuaaaguga gugagggaca ggccgauaua augaucagcu      300

uuguccgcgg ugaccaccga gauaauuccc cauucgacgg ccccggggga aaccuugcgc      360

augcuuuuca gccuggccca gguauugggg gagaugccca cuucgacgaa gaugagcguu      420

ggaccaauaa cuuuagagag uacaaucugc acaggguggc agcccaugaa uugggccacu      480

cucucggccu gucgcauuca acagacaucg gggcucugau guaucccagc uacaccuuca      540

guggagaugu ucagcucgca caagacgaua uugacgguau ccaggccaua uauggccggu      600

cccagaaccc ugugcagcca aucgggccgc aaacucccaa ggcuugcgac ucuaaauuaa      660

cauuugaugc cauuaccacg auccgcggag aggucauguu cuuuaaggac agauucuaca      720

ugaggacuaa uccuuucuau ccagaagugg agcugaacuu uauuagcgua uucuggcccc      780

agcuuccuaa uggcuuggag gcggcauacg aauuugccga ucgggacgag guucgcuucu      840

uuaaagguaa caaguacugg gcugugcagg ggcagaaugu ccugcacgga uauccaaagg      900

auaucuacuc cucauucggc uuuccccgaa ccgugaaaca cauagacgcc gcacuaagug      960

aagagaacac aggcaagacu uauuucuuug uggcuaauaa auacuggaga uaugaugaau     1020

acaagaggag cauggacccg ggguauccua aaaugauugc ccaugauuuc cccggaaucg     1080

gucacaaggu cgacgcgguu uuuaugaagg auggcuucuu uuacuucuuc caugggaccc     1140

ggcaauacaa auuugaccca aagacaaaac guauucucac ccugcagaag gccaacucuu     1200

gguucaacug ucgcaaaaau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  2880
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt3)

<400>  2880
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

aaaacauccu gaagauucuc auggacagcu acuccaaaga gucuaagaua cagaccguga      120

gaagggucac aucaguuagu cuucuggccg uguauuugac uaugaauacg agcuccuuag      180

uacuggcuaa acccaucgaa aacaccaaug auacaucuau uaagaacgug gagaagcuac      240

ggaaugcacc uaacgaagaa aauucgaaaa aggucgaaga cucaaagaac gauaaggugg      300

agcacguuaa aaauaucgag gaagccaagg uggagcaagu cgcgccagaa guaaagagca      360

aaaguacucu ccgcuccgcu ucuauugcca acaccaauag cgagaaguac gacuucgagu      420

aucugaacgg ccuuuccuac acagaacuga ccaauuugau caaaaacaua aaguggaauc      480

agaucaacgg gcucuuuaac uauucaacug gaagucagaa auucuuuggu gauaagaauc      540

gagugcaggc aauuaucaac gcccugcaag agagcggccg uacauacacc gcuaaugaca      600

ugaaagggau ugaaacguuc acugagguuc ugagagcagg auuuuaucuc ggcuacuaca      660

acgaugguuu aucuuaucug aaugacagga acuuccagga uaagugcauc ccggccauga      720

uagcuauuca gaagaauccc aacuuuaaac uugggaccgc cgugcaggac gaagucauca      780

cauccuuggg aaagcugauu ggcaaugcgu cagcaaacgc cgagguggug aauaacugug      840

ucccuguucu aaaacaauuc cgggagaauc ucaaccagua cgcuccagau uaugugaagg      900

gcacugccgu aaaugaacug aucaaaggga ucgaguuuga cuucagcgga gcagcuuacg      960

aaaaggaugu gaagaccaug cccugguaug guaaaauuga cccuuuuaua aacgagcuua     1020

aggcccuggg cuuguacggg aacaucacaa gugcgaccga augggccucu gacgucggaa     1080

uuuauuaccu cuccaaauuc ggccuguaca gcacgaaucg caacgauauc gugcagucgu     1140

uagagaaggc aguugacaug uauaaauacg guaagauagc uuuuguggcc auggagagaa     1200

uuacuuggga uuaugacggg aucggaucua auggcaagaa agucgaucau gacaaguucc     1260

uggaugacgc ugaaaaacac uaccucccaa agacauauac cuucgauaac ggcacuuuua     1320

ucauuagggc cggggacaaa guguccgagg aaaagaucaa gcggcuuuac ugggcaucac     1380

gcgagguaaa aagucaguuc caucgaguug ugggaaauga uaaggcccug gaagucggua     1440

acgcugacga cguguugaca augaaaauuu uuaauagccc cgaggaguau aaguucaaca     1500

ccaauauaaa cggcgucucc acggauaaug ggggacuaua caucgaaccu agaggcaccu     1560

uuuacacaua ugagaggacu ccacaacagu cuauuuucag ccuggaggag cucuuucggc     1620

acgaguacac ccauuaucug caggcgcguu accuugugga cggucugugg gggcaaggcc     1680

cguucuauga aaagaaccgc uugacauggu uugaugaggg aacugcagag uucuuugccg     1740

gcucaaccag aacaaguggg guucucccca ggaaguccau ccugggauac uuagcuaaag     1800

acaaggugga ucaccgguau agccugaaga aaacccuaaa uucugguuac gacgauucag     1860

acuggauguu cuacaacuau ggcuuugccg uagcacacua ccucuaugaa aaggauaugc     1920

cuacuuucau caaaaugaau aaggccauuc ugaacacgga cgucaaaagu uacgaugaaa     1980

uaaucaagaa acuuagcgac gaugcuaaca aaaauacaga guaucagaac cauauucagg     2040

aguuggccga caaguaccag ggggcaggaa ucccacuggu guccgacgau uaucucaaag     2100

accacggcua caagaaagcg ucugaaguuu acucggagau uagcaaggcu gccucccuga     2160

ccaauacuuc agugaccgca gaaaagaguc aauauuucaa cacauuuacc cuucgaggua     2220

cuuacacagg ggagacgucu aaaggcgagu ucaaggauug ggacgaaaug agcaaaaagc     2280

uggauggaac cuuggagucc cucgccaaaa auucauggag cggcuauaag acucugacag     2340

cuuacuuuac caacuaucgc gucacaucug acaauaaggu gcaguacgau guaguguucc     2400

augggguuuu aacugacaac gccgauaucu ccaauaacaa agcacccaua gcuaagguca     2460

ccggaccuag uacgggugcc gugggcagaa auaucgaauu uagcgggaaa gacucuaagg     2520

augaggacgg aaaaauugug uccuaugauu gggacuucgg cgacggugcg accucaaggg     2580

ggaagaacag uguccacgcc uacaaaaagg cuggcacaua caauguuacu cugaagguga     2640

ccgaugacaa aggagcaaca gccacugaga gcuuuaccau cgaaauuaag aacgaagaua     2700

cgacaacccc aaucacuaaa gagauggagc ccaaugacga uauaaaggaa gcuaacggcc     2760

cgauugugga ggggguaaca gucaaaggag accuaaacgg cucggaugac gccgauaccu     2820

ucuauuuuga cgugaaggaa gauggugacg uuacuaucga gcucccuuac uccgggucua     2880

gcaauuucac cuggcuggug uauaaggagg gagacgauca gaaccacauu gcaucaggca     2940

ucgacaaaaa uaacaguaag gucgguacau uuaaauccac gaagggccgg cauuacgugu     3000

ucauauauaa acacgauucu gcgagcaaua ucuccuacuc acuuaacauu aagggguugg     3060

gaaaugaaaa gcugaaagag aaggaaaaca augacagcag ugauaaagcc accguuaucc     3120

ccaacuuuaa uacuacaaug cagggcucuc uccuggggga cgauucccgc gacuauuaca     3180

gcuucgaggu gaaggaagag ggagagguaa acauugaauu agauaaaaag gacgaguucg     3240

gcgucaccug gacacugcau ccagaaucga auaucaacga uagaauaacu uacggucaag     3300

uggacgggaa uaagguguca aacaaaguca aacuuaggcc uggaaaauau uacuugcucg     3360

uuuauaagua cucuggcagu gguaauuaug agcugcgugu gaacaaauga ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  2881
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt3)

<400>  2881
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuucuuu ucuccucugc cuacucaauu gcuaacacaa      120

auagugagaa auaugacuuu gaauaccuga acggcuugag cuauacugag uuaacgaauc      180

ugauaaagaa caucaaaugg aaucagauua acgggcuauu caauuacucc accggaucuc      240

aaaaguuuuu cggugauaaa aacagagucc aggcaaucau uaaugcccuc caggaaucgg      300

gcaggacaua uacugcgaac gacaugaagg ggaucgagac cuuuacagaa guucugcggg      360

cuggauucua ccuuggcuau uacaaugaug gucugucaua cuugaacgac cgcaauuuuc      420

aggauaagug cauacccgcc augaucgcaa uucagaaaaa cccuaauuuc aagcucggga      480

ccgccgugca agacgaggua aucacuagcc ugggaaaacu gauuggcaac gcuagugcaa      540

acgccgaggu ggucaauaac ugugugccag uucucaagca guuucgagaa aauuuaaacc      600

aguaugcucc ggauuacgug aaaggcacag ccgucaauga gcugaucaag gggauagaau      660

uugacuuuuc cggagcggca uaugagaagg augugaaaac caugcccugg uacgguaaga      720

uugacccuuu caucaacgag cuuaaagccu ugggccugua ugggaauauu acgucugcua      780

cugaaugggc cagcgaugua ggaaucuacu aucuauccaa guucggccuc uacucaacca      840

accguaauga caucguucaa agucuggaga aagcagugga uauguacaag uaugguaaaa      900

uugcuuuugu cgccauggaa agaauaacau gggacuacga cgggaucgga agcaacggca      960

agaaggugga ucacgacaaa uuccuugaug acgcggagaa gcauuaucug ccaaaaacuu     1020

acaccuuuga uaauggcaca uucauuauca gggccgggga caaggugucu gaagagaaaa     1080

uaaagcgguu guauugggca ucccgcgagg ucaagucaca guuucacaga guugugggaa     1140

acgauaaagc ucucgaagua gguaaugccg acgaugugcu gaccaugaag auuuucaaca     1200

gccccgagga auacaaauuu aauacgaaca ucaacggcgu caguacugac aaugggggau     1260

uauauaucga gccuaggggc acauucuaca ccuacgaacg gacuccacag cagucuauuu     1320

ucucccugga ggagcuguuc cgccaugaau auacacacua ccuucaagcu cgauaucugg     1380

uggaugguuu gugggggcag ggccccuuuu acgagaagaa cagacuaacc ugguucgacg     1440

aaggaacggc cgaguuuuuc gcaggcagca ccaggacauc ggggguucug ccucggaaau     1500

cuauccucgg auaucuggcc aaggacaagg uggaucaucg uuacucccuu aaaaagacuc     1560

ucaauucagg uuaugacgau agugacugga uguucuacaa cuacggcuuu gcugucgcgc     1620

acuauuugua cgaaaaagau augccaaccu ucauuaagau gaauaaagca auacucaaca     1680

cagacguaaa gagcuaugau gagaucauua agaaacuguc cgacgaugcc aauaagaaca     1740

cugaguacca gaaucacauc caagaauuag cugacaaaua ucagggggcc ggaaucccgc     1800

uggugucuga ugacuaccua aaggaucaug gcuauaaaaa ggcaagcgag guuuacucag     1860

aaauuaguaa agccgcuucc cucaccaaca caagcgugac cgccgagaag ucucaguacu     1920

uuaauacuuu cacgcugcgc gguacauaua ccggggagac uucaaagggc gaauuuaaag     1980

acugggacga gaugaguaag aaacuugaug gaaccuugga aagccuggca aagaacuccu     2040

ggucuggcua caaaacacuc accgcguauu ucacuaauua cagagucaca ucggacaaca     2100

aggugcagua ugaugucgug uuucacgggg uucugacgga caaugcugau auaagcaaca     2160

acaaggcccc caucgcaaaa gugaccggac cuuccacugg ugccguaggc aggaauauug     2220

aguucucagg gaaggacagu aaagaugaag acggaaagau cgucucuuac gauugggacu     2280

uuggcgaugg ugcuacaagc cgggggaaaa acuccgugca ugccuauaag aaggcaggca     2340

ccuacaaugu uacacuuaaa gugacugacg auaagggagc uaccgccacg gagucauuca     2400

ccauugagau caaaaacgaa gacacaacua ccccaauaac aaaggagaug gaacccaaug     2460

acgauaucaa agaggcgaac ggcccuauug ucgaaggggu gacuguaaag ggagaccuga     2520

auggcagcga ugacgccgau accuuuuacu ucgacgugaa ggaggauggu gacguuacga     2580

ucgaguugcc auauucuggg uccaguaacu uuacauggcu cgucuacaaa gaaggagaug     2640

accaaaauca cauugcuagc ggcaucgaua agaacaauuc uaaagugggu accuucaagu     2700

ccacuaaagg ccgacacuau guguucauau acaagcauga cucagcaagu aacauuagcu     2760

auucgcugaa uaucaaaggg uuaggaaacg agaagcugaa ggaaaaagag aauaacgacu     2820

ccucugauaa ggccacaguc auucccaacu uuaauaccac uaugcagggc agccuacucg     2880

gggacgauuc acgcgacuac uauaguuucg aaguuaaaga ggagggagaa gugaacaucg     2940

agcuggauaa gaaagacgaa uuuggcguga ccuggacacu ucacccggag uccaauauaa     3000

acgauagaau cacguacggu cagguagacg ggaauaaggu cucuaacaag gugaaauuga     3060

ggccuggaaa guacuaucug cucguuuaca aauauagcgg cuccgguaau uacgagcugc     3120

gggugaacaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  2882
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt3)

<400>  2882
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuucuuu ucuccucugc cuacucaaug aaaaagaaca      120

uucugaaaau auugauggac aguuauagca aggaguccaa aauccagaca gucagaaggg      180

uuacuucugu gucguuacug gcuguauacc uaacgaugaa uaccucaagc cucgugcugg      240

caaagcccau ugaaaacaca aaugauacua gcaucaagaa cgucgagaaa cuucggaaug      300

ccccuaacga agaaaauucc aagaaagugg aagacucuaa gaacgauaaa guugagcacg      360

ugaagaauau ugaggaagcg aaggucgagc aaguggcucc agaaguaaaa agcaagucca      420

cccugcgcuc agccagucga cguagaagga aacggaucgc aaacacaaau agcgagaagu      480

augacuuuga guacuugaac ggccucucuu auaccgaacu gacuaaucug aucaaaaaca      540

uaaaguggaa ucagauuaac ggacucuuca acuacuccac aggaucacag aaauuuuucg      600

gugauaagaa ucgcguucag gccaucauua acgcuuuaca agagagcggc agaaccuaua      660

cggcaaauga caugaagggg aucgaaacuu uuaccgaggu gcugagggcc ggauucuacc      720

uuggcuacua uaacgauggu uugaguuacc ugaaugaccg gaacuuucag gauaaaugca      780

uaccggcuau gauugccauc cagaagaauc ccaacuucaa acuagggaca gcgguccagg      840

acgaagugau uacuucucuc ggaaagcuga ucggcaaugc auccgccaac gcugaggugg      900

ucaauaacug uguuccugug cuuaaacaau uucgcgagaa ucugaaccag uaugccccag      960

auuacguaaa gggcaccgca gugaaugaau ugaucaaggg gauugaguuc gacuuuagcg     1020

gagcugccua ugaaaaagau gucaagacaa ugcccuggua cgguaaaaua gacccuuuca     1080

ucaacgagcu caaggcgcug ggcuuauaug ggaacauuac cucggccacg gaaugggcau     1140

cugacguggg aaucuacuac cuguccaaau ucggccucua uucaacuaau cgaaacgaua     1200

uaguucagag ucuugagaag gcuguggaca uguacaagua ugguaaaauu gccuuugucg     1260

cuauggagag aaucacaugg gauuacgacg ggaucggaag caauggcaag aaaguggauc     1320

augacaaguu ccuggaugac gccgaaaaac acuauuugcc aaagaccuac acuuuugaua     1380

acggcacauu cauuaucagg gcaggggaca agguauccga ggagaaaauu aagcggcuau     1440

auugggccuc ucgugagguu aaaagccagu uucaucgcgu ggucggaaau gauaaggcuc     1500

uggaaguggg uaacgcggac gacguccuca ccaugaaaau auucaauuca cccgaggagu     1560

acaaguuuaa cacgaauauc aacggcguga guaccgauaa ugggggacug uacauugaac     1620

cuagaggcac auucuauacu uacgagagga ccccacaaca guccaucuuu agccuugagg     1680

aacuguuccg gcacgaguau acacauuacu ugcaggcacg auaucucguu gacggucugu     1740

gggggcaagg cccguuuuac gagaaaaacc gcuuaacuug guucgaugaa ggaaccgccg     1800

aauuuuucgc uggcucuaca agaaccucag gggugcugcc caggaagagu auccuaggau     1860

aucucgccaa ggacaaagua gaucaccggu acagccugaa gaaaacucuu aauuccgguu     1920

acgacgauuc ugacuggaug uucuauaacu acggcuuugc agucgcccac uauuuguacg     1980

agaaggauau gccuacguuc auuaaaauga auaaggcuau acugaacaca gacgugaagu     2040

cguaugauga aaucauuaaa aagcucagcg acgaugccaa caaaaauacc gaguaccaga     2100

accauaucca ggagcuggca gacaaguauc agggggcggg gauuccacuu guuuccgacg     2160

auuaccugaa agaccacggc uacaagaagg cuucagaagu guauagugag aucucuaaag     2220

ccgcaaguuu gacuaauacc uccgucacag ccgaaaaguc acaauacuuu aacaccuuca     2280

cucuccgcgg uacauauacg ggggagacca gcaaaggcga auuuaaggau ugggacgaga     2340

ugucuaaaaa gcuggaugga acuuuagagu cccuggcuaa gaauaguugg agcggcuaca     2400

aaacacuaac cgccuauuuc acaaacuaca gagugacuuc ugacaauaag guacaguaug     2460

augugguuuu ucaugggguc cucaccgaca acgcagauau auccaauaac aaagcuccca     2520

ucgccaaggu gacgggaccu ucaaccggug cggugggcag gaauauugag uucaguggga     2580

aagacagcaa ggaugaagac ggaaaaaucg ucucguacga uugggacuuu ggcgacggug     2640

ccacaucccg ugggaagaac ucuguucacg cuuacaagaa agcaggcacu uauaauguga     2700

cccugaaggu gacagaugac aaaggagcca cugcuaccga gagcuucacg auugaaauca     2760

agaacgaaga uacaaccacu ccaauaacaa aagagaugga gcccaaugac gauauuaagg     2820

aagccaacgg cccgaucgua gaggggguca ccgugaaggg agaccuuaac ggcucagaug     2880

acgcagauac uuuuuacuuc gacguuaaag aagaugguga cgugaccauu gaguugccuu     2940

auaguggguc cucuaauuuu acauggcugg ucuacaagga gggagacgau cagaaccaca     3000

ucgcgagcgg cauagacaaa aauaacucca agguggguac guucaaauca accaagggcc     3060

ggcauuaugu uuucaucuac aagcacgaua gcgccaguaa uauuucuuau ucccucaaca     3120

ucaaagggcu gggaaaugaa aaguuaaaag agaaggaaaa caaugacagc ucggauaaag     3180

cuacugugau ucccaacuuu aauacaacca ugcagggcuc acugcuuggg gacgauucuc     3240

gagacuacua caguuucgag guaaaggaag agggagaggu caacaucgaa uuggauaaga     3300

aagacgaguu uggcgugaca uggacucucc auccagaauc caauauaaac gauagaauua     3360

ccuaugguca aguggacggg aauaagguca gcaacaaagu uaagcugagg ccuggaaaau     3420

acuaucuacu gguguacaag uauucuggca gcgguaauua cgagcuccgc guaaacaagu     3480

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  2883
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt3)

<400>  2883
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugaagau cauucucaau agaggcaaaa ccaugaagag gaaaugccuu agcaagcggc      120

ugauguuggc cauaacaaug gcuacuaucu uuacggugaa cuccaccuua cccauuuacg      180

cagccgucga caaaaauaac gcgacagcug ccguucagaa ugagucuaag cgcuauacug      240

ugucauaccu gaagacccua aacuauuacg aucucguaga ccugcuugug aaaacagaaa      300

ucgagaaucu gccugauuug uuccaauaua guagcgacgc aaaggaauuu uacgggaaca      360

aaacccgaau guccuucauu auggaugaga ucggacguag agccccacag uauacugaaa      420

uagaccacaa ggguaucccg acacucgucg aggugguuag ggcuggcuuu uaccuggggu      480

uccauaauaa agagcugaac gaaauuaaua agcggucuuu uaaggagcgc gugauccccu      540

cgauucucgc aauccagaaa aacccuaauu ucaaguuagg aaccgaaguc caggauaaaa      600

uagugucagc cacgggccug cuugcuggua acgagacugc cccacccgag guaguuaaua      660

acuuuacccc uauuuugcaa gacuguauca agaacauuga uagauacgcg cuggacgauc      720

uaaaaagcaa ggcacucuuc aaugugcugg ccgcuccaac auaugacauc acugaauacc      780

uuagggccac caaagagaag cccgaaaaca caccuuggua ugggaagauc gauggauuua      840

uuaaugagcu gaaaaaguug gcacucuacg gcaaaauaaa cgacaauaac aguuggauca      900

uugacaaugg caucuaucac auagcuccac uggggaaguu acauuccaac aauaaaauug      960

gaaucgaaac ccugacggag gucaugaagg uguacccgua ucucucuaug cagcaccuuc     1020

agagcgccga ucagaucaag cggcauuacg acuccaaaga ugcggagggu aacaagauuc     1080

cccuggacaa auucaagaaa gaaggcaagg agaaguacug cccuaaaacu uauacauuug     1140

augacgggaa ggugaucauu aaagccggag cacgcgucga agaggaaaag guuaaacgau     1200

uguacugggc uucaaaggag gugaauaguc aauucuucag aguauauggc auagauaagc     1260

cacuagagga agguaacccc gacgauaucc ugaccauggu gauuuacaau agcccugagg     1320

aauauaaacu caacucuguc cuguacgggu augacacuaa uaacggaggc auguacaucg     1380

agccagaagg cacauuuuuc accuacgaga gggaggccca ggaauccacg uauacccuug     1440

aggaacuguu ucggcacgag uacacacacu auuugcaggg gcguuacgcu gugcccggac     1500

aguggggucg cacuaagcuc uaugauaacg acagacugac cugguacgag gaaggcgggg     1560

ccgaguuauu cgcaggauca acaaggacua gcggcauccu gccgcggaaa aguauuguuu     1620

cuaauauaca uaacaccaca cgaaauaacc gcuauaagcu auccgacacc gugcacagca     1680

aauacggugc cucguuugag uucuacaauu augcuuguau guuuauggau uacauguaua     1740

acaaggacau ggggauccuc aauaaacuga acgaucuugc gaagaauaac gacgucgaug     1800

gcuacgacaa uuauauuaga gauuugucuu ccaacuacgc acugaaugac aaguaucaag     1860

aucauaugca ggaaaggauc gacaacuacg aaaaucucac ugugccuuuc guagccgaug     1920

acuaccuggu ucggcacgcu uauaaaaacc ccaacgagau uuacucagag aucagugaag     1980

uggccaaacu uaaggaugca aagagcgagg ucaaaaaguc ccaguauuuu ucuacguuca     2040

cacugcgcgg aagcuacacc ggcggggccu caaagggaaa auuggaagac caaaaggcua     2100

ugaauaaauu uauagacgau agucucaaga aacuggacac uuauuccugg agcgguuaca     2160

agaccuuaac agccuauuuc accaacuaca agguggauuc uucaaauaga gucacuuacg     2220

acgugguuuu ucacggcuau cugccaaacg agggggauag uaaaaauagc cuaccuuacg     2280

gaaagaucaa cggcacauau aaagguacgg aaaaggagaa aauuaaguuc uccucugagg     2340

ggucguucga ccccgauggc aagaucguga gcuacgaaug ggacuuugga gauggcaaua     2400

aauccaacga ggaaaaucca gagcauucau augacaaggu agggaccuac acugucaaac     2460

ucaaggugac agaugacaaa ggagaaaguu cuguuagcac cacaacugca gagauuaagg     2520

aucuguccga gaacaaacuu cccgugaucu auaugcacgu cccuaaguca ggugcguuga     2580

aucagaaggu gguauucuac ggcaaaggga ccuacgaccc agacggaagc auagcuggcu     2640

aucaguggga uuuuggugac gggucugauu ucuccaguga acagaacccg agccaugugu     2700

acacgaagaa aggcgaguau accguuacac ugagggucau ggacucuucc ggacaaaugu     2760

cagaaaagac uaugaaaauu aagaucaccg aucccgugua cccuauuggc acagagaagg     2820

agccaaauaa caguaaagaa acugccagcg ggcccaucgu gccuggaaua ccagucucgg     2880

gcaccaucga gaauacgucc gaccaggauu auuuuuacuu cgacguuauu acacccggug     2940

aagugaagau cgauauuaac aaacucgggu auggaggcgc aaccugggug guauacgacg     3000

agaacaauaa cgccgucucu uacgcuacug augacgguca gaaucugagc ggcaaguuua     3060

aagccgacaa gccggggcgu uauuacaucc acuuauauau guucaacgga ucauacaugc     3120

cuuaucggau aaauauugaa ggcagugugg ggcgaugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  2884
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt3)

<400>  2884
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

gaaaaugccu gagcaagagg cucaugcuug ccaucaccau ggcuacaauu uucacuguga      120

acuccacgcu gcccauauac gcagccgucg acaaaaauaa cgcgaccgcu gccguucaga      180

augagucuaa gcgguauaca gugucauacu ugaaaacuuu aaacuauuac gaucugguag      240

accuacucgu gaagaccgaa aucgagaauc ugccugaucu uuuucaauau aguagcgacg      300

caaaggaguu cuacggcaac aaaacacgca uguccuuuau uauggaugaa aucgggcgac      360

gugccccaca guauaccgaa auugaccaca agggaauccc gacucugguc gaggugguua      420

gagcugguuu cuacuugggc uuucauaaua aagagcucaa cgaaauaaau aagaggucuu      480

ucaaagagcg ggugaucccc ucgauucugg caauccagaa gaacccuaau uuuaagcugg      540

ggacagaagu ccaggauaaa auugugucag ccaccggacu cuuagcuggc aacgagacgg      600

ccccacccga gguaguuaau aacuucacuc cuauccugca agacuguaua aagaauauug      660

aucgcuacgc gcuugacgau uugaaaagca aggcacuguu uaacgugcua gccgcuccaa      720

ccuaugacau cacagaauac cucagagcca cuaaagagaa gcccgaaaac accccuuggu      780

augguaaaau ugauggguuc aucaaugagc ugaagaagcu ggcacuguac ggaaaaauca      840

acgacaauaa caguuggauu auagacaaug gcaucuauca cauugcucca uugggcaagc      900

uccauuccaa caauaaaauc gggauagaaa cacugaccga ggucaugaag guguacccgu      960

auuuaucuau gcagcaccuu cagagcgccg aucagauuaa aaggcauuac gacuccaagg     1020

augcggaggg aaacaagauc ccccucgaca aauuuaagaa agaagguaag gagaaauacu     1080

gcccuaagac guauacuuuc gaugacggca aggugaucau uaaagccggg gcacgggucg     1140

aagaggaaaa gguuaaacgc cuuuacuggg cuucaaagga ggugaauagu caauuuuucc     1200

gaguauaugg aaucgauaaa ccacuggagg aaggcaaccc cgacgauauu uugacaaugg     1260

ugauauacaa uagcccugag gaauauaagc uaaacucugu ccuguacggu uaugacacca     1320

auaacggggg aauguacauc gagccagaag gcacuuucuu uacauacgag agagaggccc     1380

aggaauccac cuauacgcuc gaggaacugu ucaggcacga guacacccac uaucuucagg     1440

gccgguacgc ugugcccggg caguggggac guacaaagcu guaugauaau gaccgcuuga     1500

cuugguacga ggaagguggc gccgagcucu uugcaggguc aaccagaaca agcggcauuc     1560

ugccgaggaa aaguaucguu ucuaacaucc auaacacuac ccggaauaac cgauauaagu     1620

uauccgacac agugcacagc aaauacggag ccucguucga auuuuacaau uaugcuugua     1680

uguucaugga uuacauguau aacaaggaca uggguauucu gaauaaacua aacgaucucg     1740

cgaagaauaa cgacgucgau ggguacgaca auuauauacg cgaucugucu uccaacuacg     1800

cacuuaauga caaauaucaa gaucauaugc aggagagaau cgacaacuac gaaaauuuga     1860

ccgugccuuu uguagccgau gacuaccugg uuaggcacgc uuauaagaac cccaaugaga     1920

uuuacucaga gaucagugaa guggccaagc ucaaagaugc aaagagcgag gucaaaaagu     1980

cccaguauuu cucuacuuuu acgcugcggg gcagcuacac aggaggcgcc ucaaaaggga     2040

aacuugaaga ccaaaaggcu augaacaagu ucauugacga uagucugaag aaauuggaca     2100

ccuauuccug gagcggauac aagacucuca ccgccuauuu uacaaacuac aaaguggauu     2160

cuucaaaucg cgucaccuac gacgugguuu uccacgguua ucugccaaac gagggcgaua     2220

guaagaauag cuuaccuuac gggaagauca acggaacuua uaaaggcaca gaaaaggaga     2280

aaauaaaguu uuccucugag gguucguucg accccgaugg gaaaaucgug agcuacgaau     2340

gggacuucgg cgauggaaau aaguccaacg aggaaaaucc agagcauuca uaugacaagg     2400

uaggcacgua caccgucaaa cugaagguga cugaugacaa aggggaaagu ucuguuagca     2460

caaccacagc agagauuaag gaucuauccg agaacaaacu ccccgugauc uauaugcacg     2520

ucccuaaguc aggagcgcug aaucagaaag ugguauuuua cgguaagggc acuuacgacc     2580

cagacgggag cauugcugga uaucaguggg auuucggcga cgguucugau uuuuccagug     2640

aacagaaccc gagccaugug uacaccaaga aaggggagua uacgguuacc cuuagaguca     2700

uggacucuuc cggccaaaug ucagaaaaga caaugaaaau caagauaacu gaucccgugu     2760

acccuauugg aaccgagaaa gagccaaaua acaguaagga aacagccagc ggccccaucg     2820

ugccugggau uccagucucg ggaacuaucg agaauaccuc cgaccaggau uauuucuacu     2880

uugacguuau aacgcccggc gaagugaaga ucgauauuaa caaauugggu uaugggggag     2940

caacaugggu gguauacgac gagaauaaca acgccgucuc uuacgcuacc gaugacggcc     3000

agaaucugag cgguaaguuc aaagccgaca agccgggcag guauuacauc caccucuaua     3060

uguuuaacgg gucauacaug ccuuaucgua uuaauaucga aggaagugug ggccggugag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  2885
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt3)

<400>  2885
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuucuuu ucuccucugc cuacucaguc cagaacgaga      120

guaaaagaua uacaguuagc uaccugaaga cuuugaauua uuacgacuua guggaucugc      180

uaguaaaaac ggaaauugag aaccuccccg accuguuuca auauuccucu gaugcuaagg      240

aguucuacgg caauaaaacc aggaugucgu uuauaaugga cgaaaucggc cggcgcgcac      300

cucaguauac agaaauugau cacaagggaa ucccaacucu uguggagguc gugcgagccg      360

guuucuaccu gggcuuucau aacaaggagu ugaaugaaau uaacaaacgu ucauucaagg      420

agagaguuau cccgagcaua cucgcgaucc agaaaaaucc caacuuuaag cuggggaccg      480

aagugcagga caaaauuguc agugcuacag gacugcucgc cggcaaugag accgcaccuc      540

cagagguggu aaacaauuuc acucccaucu uacaagauug cauuaagaac aucgacaggu      600

acgcccugga ugaccuuaag uccaaggcuu uguuuaaugu ucuggcagcc ccuacauaug      660

auauaaccga auaccuacgg gcuacgaagg agaaaccaga aaacacuccc ugguauggua      720

agauugacgg guucaucaau gagcucaaaa agcuggcccu uuacggaaaa auuaacgaua      780

acaauucuug gaucaucgac aacggcauuu aucacauagc gccucugggc aaguugcaua      840

gcaauaacaa gaucgggauu gaaacccuca cagaggugau gaaagucuac ccauaucugu      900

ccaugcagca cuuacaguca gcagaccaga ucaagcgcca uuacgauagu aaagacgccg      960

agggaaauaa gauaccgcug gauaaauuua agaaggaagg uaaagagaag uacuguccca     1020

aaacuuauac cuucgacgau ggcaagguga uuaucaaagc uggggccaga guggaagagg     1080

aaaaggucaa gaggcucuac ugggcaagca aagagguuaa cucucaauuc uuucgggugu     1140

auggaaucga caagccucuu gaggaaggca auccagauga cauucugaca augguaaucu     1200

acaacucccc cgaggaauau aaacuaaauu caguguugua cgguuaugau accaacaaug     1260

ggggaaugua cauugagccu gaaggcacgu ucuuuacuua cgagcgcgag gcucaggaaa     1320

gcacauauac ccuggaggaa cucuuccgac acgaguacac ucacuaucug cagggcagau     1380

acgccguccc agggcagugg ggaaggacaa aacuuuauga caacgaucgg cugaccuggu     1440

acgaggaagg uggcgcggag uuguuugccg ggaguacgcg uaccucugga auacuccccc     1500

gcaaauccau cgugagcaau auucauaaca caacuagaaa uaacagguau aagcugucgg     1560

acaccguuca cucuaaguac ggcgcauccu ucgaauuuua caacuaugcu ugcauguuca     1620

uggacuacau guauaauaaa gauaugggua ucuuaaacaa gcugaaugac cuagccaaaa     1680

acaaugaugu ggacggguac gauaacuaua uccgggaccu cucaaguaau uacgcucuga     1740

acgauaagua ucaagaccau augcaggagc gaauugauaa uuacgaaaac cuuacagucc     1800

cguuuguggc cgacgauuac uugguacgcc acgcauauaa aaauccuaac gagauauaca     1860

gcgagaucuc cgaaguugcc aagcugaaag acgcuaaguc ugaggugaag aaaagccagu     1920

auuucucaac uuuuacccuc agaggcaguu acacaggagg cgcguccaag gggaaacugg     1980

aagaucaaaa ggcaaugaau aaauucauug acgacagccu uaagaagcug gauaccuauu     2040

cuuggucagg auacaaaacu uugacggccu auuuuacaaa cuacaagguc gacaguagca     2100

auagggugac cuacgauguc guguuccacg guuaucuccc caacgagggc gacuccaaaa     2160

acucucugcc auacgggaag aucaauggaa cuuauaaagg caccgaaaag gagaagauua     2220

aauucucgag cgaggguucc uuugauccug acgggaagau cguuucauac gaaugggauu     2280

ucggcgacgg aaacaaaagu aaugaggaaa accccgagca uucuuaugau aaggugggca     2340

cauacaccgu aaaauuaaag gucacugacg auaaggggga aagcuccgug ucaacaacga     2400

ccgcugagau aaaagaccug agcgagaaua agcuaccagu uaucuauaug cacgugccca     2460

aaucuggagc ccucaaccag aaggucgugu uuuacgguaa aggcacuuac gauccugacg     2520

gguccauugc aggauaucag ugggacuucg gcgaugguag ugacuuuagc ucugaacaga     2580

auccauccca uguauacaca aagaaagggg aguauaccgu gacacugcgg guuauggauu     2640

caaguggcca aaugagcgaa aagacuauga agaucaaaau uaccgacccg gucuacccca     2700

ucggaacgga gaaggagccu aacaauucga aagaaaccgc cuccggccca auagugcccg     2760

ggauuccugu gucuggaaca aucgagaaca cuagcgauca ggacuauuuc uacuuugaug     2820

ucauuacccc aggcgaaguu aagaucgaca uaaauaaacu ugguuauggg ggagcuacau     2880

ggguggugua cgaugagaac aauaacgccg uaucauacgc aacugacgau ggccagaauu     2940

ugagugguaa guucaaggcg gacaaacccg gccgcuauua cauccaccug uauauguuua     3000

acggguccua caugccguau agaauuaaca ucgaaggauc ugucgggagg ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  2886
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt3)

<400>  2886
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuucuuu ucuccucugc cuacucaaug aaaagaaagu      120

gccugaguaa aagguugaug uuagcuauua caauggcaac uauauuuacg gucaacagca      180

cccugcccau cuaugccgcg guugacaaga auaacgcuac agccgcacgg cgccgacgua      240

aaagagugca gaaugagucc aagagguaca cuguaucuua ucuaaagacc cucaacuacu      300

augaucuggu ggaccuucug gucaaaacag aaauugagaa uuugccugau cucuuccaau      360

acucgucaga cgccaaggaa uuuuauggca acaaaacccg gaugagcuuc aucauggaug      420

agauugggcg cagagcucca caguacacug aaaucgacca caagggaaua ccgacacugg      480

uggagguugu gagggcaggu uuuuaccugg gcuuccauaa uaaagagcuc aacgaaauca      540

auaagcggag uuuuaaggag cgcgucauuc ccuccaucuu agccauucag aaaaacccua      600

auuucaagcu ggggaccgaa gugcaggaua aaaucguauc ugcuacggga cuuuuggccg      660

gcaacgagac ugcgccaccc gagguuguga auaacuuuac cccuauacug caagacugua      720

uuaagaauau cgaucgauau gcacuagacg aucucaaaag caaggcccug uucaacgucc      780

uugcugcccc aacauacgac auuacugaau aucugagagc aaccaaagag aagcccgaaa      840

acacaccuug guacgguaag aucgaugggu uuaucaauga guugaaaaag cucgcucugu      900

auggaaaaau uaacgacaau aacuccugga uaaucgacaa uggcauuuac cacaucgccc      960

cauuaggcaa gcugcauuca aacaauaaaa uagggauuga aacccucacg gaggugauga     1020

agguguaucc guaccuuagu augcagcauc ugcagagcgc ggaucagauc aagaggcacu     1080

acgacucuaa agaugccgag ggaaacaaga uccccuugga caaauucaag aaagaaggua     1140

aggagaagua uugcccuaaa acuuacacau ucgaugacgg caaggucauu aucaaagcag     1200

gggcucgggu ugaagaggaa aaggugaaac gucuauauug ggccuccaag gagguaaauu     1260

cacaauuuuu ccgcguguac ggaauugaua agccacugga ggaaggcaac cccgacgaua     1320

uacucaccau ggucaucuau aauagcccug aggaauacaa acugaacagu gugcuuuaug     1380

guuacgacac uaauaacggg ggaauguaca uugagccaga aggcacauuu uucaccuaug     1440

agagagaggc ucaggaaucu acguacaccc uggaggaauu guuuaggcac gaguauacac     1500

acuaccucca gggccgguau gccguucccg ggcagugggg acgaacuaag cuguacgaua     1560

augaccgcuu aaccugguau gaggaaggug gcgcagagcu guucgccggg uccacaagaa     1620

cuagcggaau ccuaccgagg aaaucgaucg ugucuaacau ucauaacacc acacggaaua     1680

accgcuacaa gcucuccgac accguccacu caaaauacgg cgcuaguuuu gaguucuaua     1740

auuacgcgug uauguuuaug gauuauaugu acaacaagga cauggguaua cugaauaaac     1800

uuaacgauuu ggcaaagaau aacgacgugg auggguauga caauuacauc agagaucuga     1860

gcuccaacua ugcccucaau gacaaguacc aagaucauau gcaggaaagg auugacaacu     1920

acgaaaaucu gacuguaccu uucguugcug augacuaucu ugugcgucac gccuacaaaa     1980

accccaauga gaucuauucu gagauuagcg aagucgcaaa gcugaaagau gccaagucag     2040

aggugaaaaa gagucaguac uuuuccacgu ucacauugcg gggcagcuau accggaggcg     2100

cuucuaaggg gaaacucgaa gaccaaaagg ccaugaacaa auuuaucgac gauucacuga     2160

agaaauuaga cacuuacagu uggagcggau auaagacccu gacagcauac uucaccaacu     2220

acaaggucga uuccucuaau cgagugacuu augacguugu guuccacggu uaccuaccaa     2280

acgagggcga uucgaaaaau agccucccuu augggaagau aaacggaaca uacaaaggca     2340

cggaaaagga gaaaaucaag uuuuccucag aggguaguuu cgaccccgau gggaagauug     2400

uaucuuauga augggacuuu ggcgauggaa auaaaagcaa cgaggaaaau ccagagcauu     2460

ccuacgacaa ggucggcacc uauacuguga aacugaaggu uacagaugac aaaggggaau     2520

caagcguguc uaccacaacu gcggagauca aggaucuuuc cgagaacaaa uugcccguca     2580

uuuacaugca cgugccuaag aguggagcuc ugaaucagaa gguaguguuc uacgguaaag     2640

gcaccuauga cccagacggg agcaucgccg gauaccagug ggauuuuggc gacgguucug     2700

auuucuccuc agaacagaac ccgagucaug uuuauacgaa gaaaggggag uacaccguca     2760

cacucagagu gauggacagc ucgggccaaa uguccgaaaa gacuaugaaa auaaagauua     2820

ccgaucccgu guauccuauc ggaacagaga aggagccaaa uaacucuaaa gaaacugcaa     2880

gcggccccau ugucccuggg aucccaguuu caggaaccau agagaauacg agugaccagg     2940

auuacuuuua uuucgacgug aucacacccg gcgaagugaa gauugauauc aacaaacugg     3000

guuacggggg agccaccugg guagucuacg acgagaauaa caacgcugug uccuaugcca     3060

cugaugacgg ccagaauuua ucugguaagu uuaaagcaga caagccgggc agguacuaua     3120

uucaccugua cauguucaac gggagcuaua ugccuuaccg caucaauaua gaaggauccg     3180

uuggccggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  2887
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt3)

<400>  2887
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuugggg cugcauuugc caugccccug ccuccacacc      120

cgggacaucc cgguuacauu aacuucagcu augagguguu gacaccuuua aagugguacc      180

aguccauaag accacccuau ccuucuuacg gcuaugaacc aaugggaggg uggcugcacc      240

aucaaaucau ucccguccua ucacagcagc acccuccaac ucauacgcuc cagccgcacc      300

accauauccc cguugugccu gcgcaacagc caguaauucc ccagcagccu augaugccag      360

ugcccggcca acacaguaug accccgaucc agcaucacca gccuaaucug cccccuccag      420

cucagcaacc cuaccagcca cagcccgucc aaccucagcc acaccagccg augcagcccc      480

aaccuccagu gcaucccaug cagccucuuc caccccagcc gccucugcca cccauguuuc      540

cuaugcagcc cuugccaccu augcuccccg accugacacu ggaggccugg ccaagcacug      600

auaaaaccaa gagggaagag guugacugag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  2888
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt3)

<400>  2888
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccaca cccgggccau cccggguaca ucaacuucag cuaugaggug cucaccccuc      120

uuaaguggua ccaguccauu agaccacccu auccuucuua cggauaugaa ccaaugggug      180

gcuggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  2889
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt3)

<400>  2889
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccaca cccgggccau cccggguaca ucaacuucag cuaugaggug cucaccccuc      120

uuaaguggua ccaguccauu agaccacccc cuaugcugcc agacuugaca uuagaagccu      180

ggcccucuac ugauaaaacg aagagggagg aagucgacug aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  2890
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt3)

<400>  2890
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcucc cagaacccug guccuccuuc ugagcggcgc auuggccuua acacagacuu      120

gggcgaugcc ucugccaccg caccccgggc auccuggaua caucaacuuc uccuaugagg      180

uucuaacgcc acucaagugg uaccaaucua uuaggccccc uuauccauca uacgguuaug      240

aacccauggg cgggugguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  2891
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt3)

<400>  2891
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcucc cagaacccug guccuccuuc ugagcggcgc auuggccuua acacagacuu      120

gggcgaugcc ucugccaccg caccccgggc auccuggaua caucaacuuc uccuaugagg      180

uucuaacgcc acucaagugg uaccaaucua uuaggccccc uccaaugcug cccgaccuua      240

cccuggaggc uuggccuuca acagauaaaa cuaagcggga agaaguggac ugaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  2892
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt3)

<400>  2892
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cucguggggg cugcauuugc caugccccuu ccuccacacc      120

cgggacaucc cgguuacauu aacuucagcu augagguccu gacaccuuug aagugguacc      180

aguccaugau aagaccaccc uauucuucau acggcuauga accuauggga gggugguuac      240

accaucaaau cauuccaguu gugagucagc agcacccccu gacucauacg cuacagagcc      300

accaccauau cccuguagug ccagcgcaac agccgagggu ccggcagcag gcucucaugc      360

ccgugccugg ccaacagucc augaccccaa cacagcacca ucagcccaau cugccucuuc      420

cagcccaaca gcccuuucag ccgcaaccug uucagcccca gccacaccag ccuaugcaac      480

cccagccacc cgugcagccu augcagccac uguugccgca acccccucuc ccacccaugu      540

ucccucugcg cccacugccc ccgauucucc cugacuuaca ccuggaggca uggccagcca      600

cugauaaaac caagcaggaa gaggucgacu gaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  2893
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt3)

<400>  2893
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccaca cccgggccau cccggguaca ucaacuucag cuaugaggug cucaccccuc      120

uuaaguggua ccaguccaug auuagaccac ccuauucuuc auacggauau gaaccuaugg      180

guggcuggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  2894
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt3)

<400>  2894
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccaca cccgggccau cccggguaca ucaacuucag cuaugaggug cucaccccuc      120

uuaaguggua ccaguccaug auuagaccac ccccuauacu gccagacuug cacuuagaag      180

ccuggcccgc uacagauaaa acuaagcaag aggaagucga cugaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  2895
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt3)

<400>  2895
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcucc cagaacccug guccuccuuc ugagcggcgc auuggccuua acacagacuu      120

gggcgaugcc ucugccaccg caccccgggc auccuggaua caucaacuuc uccuaugagg      180

uucuaacgcc acucaagugg uaccaaucua ugauuaggcc cccuuauuca aguuacgguu      240

augaaccaau gggcgggugg ugaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  2896
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt3)

<400>  2896
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcucc cagaacccug guccuccuuc ugagcggcgc auuggccuua acacagacuu      120

gggcgaugcc ucugccaccg caccccgggc auccuggaua caucaacuuc uccuaugagg      180

uucuaacgcc acucaagugg uaccaaucua ugauuaggcc cccuccaaua cugcccgacc      240

uucaccugga ggcuuggccu gccaccgaua aaacaaagca ggaagaagug gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  2897
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt3)

<400>  2897
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuugggg cugcauuuag caugccccug ccuccacacc      120

cgggacaucc cgguuacauu aacuucuccu augagguguu gacaccuuua aagugguacc      180

agaauaugau aagacaccca uauacuucuu acggcuauga acccauggga ggguggcugc      240

aucaccaaau cauuccuguc guuucacagc agacgccaca gagucaugcc cuacaacccc      300

accaccauau cccuauggug ccagcgcagc agccgggcau uccccagcaa ccuaugaugc      360

cacuccccgg ucagcacagc augaccccua cacagcauca ccagccaaac cugccccuuc      420

cggcucaaca gccuuuucag ccccaaccag uacagccuca gccccaccag ccacugcaac      480

cccagucccc uaugcaucca auccagccgu ugcuccccca gccuccacug cccccuaugu      540

ucucuaugca aucgcugcuc ccagacuuac cccuggaggc cuggccggca acugauaaaa      600

ccaagaggga agagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  2898
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt3)

<400>  2898
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccaca cccgggccau cccggguaca ucaacuucag cuaugaggug cucaccccuc      120

uuaaguggua ccagaauaug auuagacacc cauauacauc cuacggauau gaacccaugg      180

guggcuggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  2899
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt3)

<400>  2899
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccaca cccgggccau cccggguaca ucaacuucag cuaugaggug cucaccccuc      120

uuaaguggua ccagaauaug auuagacacc caucccuguu gcccgacuua ccucuggaag      180

ccuggccagc uacagauaaa acuaagaggg aggaagucga cugaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  2900
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt3)

<400>  2900
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcucc cagaacccug guccuccuuc ugagcggcgc auuggccuua acacagacuu      120

gggcgaugcc ucugccaccg caccccgggc auccuggaua caucaacuuc uccuaugagg      180

uucuaacgcc acucaagugg uaccaaaaua ugauuaggca ccccuauacc ucuuacgguu      240

augaaccuau gggcgggugg ugaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  2901
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt3)

<400>  2901
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcucc cagaacccug guccuccuuc ugagcggcgc auuggccuua acacagacuu      120

gggcgaugcc ucugccaccg caccccgggc auccuggaua caucaacuuc uccuaugagg      180

uucuaacgcc acucaagugg uaccaaaaua ugauuaggca ccccucucug cuuccugacc      240

ugccauugga ggcuuggccc gccaccgaua aaacaaagcg ggaagaagug gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  2902
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt3)

<400>  2902
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuugggg cugcauuuag caugccccug ccuccacacc      120

cgggacaucc cgguuacauu aacuucuccu auauaagaca cccuuacaca ucuuauggcu      180

acgagccaau gggagggugg uugcaucacc agaucauucc cguggucuca caacagacuc      240

cucagaguca ugccuuacag ccacaccacc auauccccau gguuccugcg caacagccag      300

gcauuccgca gcagcccaug augccucugc caggucaaca cagcaugacg cccacccagc      360

aucaccagcc uaaucuacca cuccccgcuc agcaaccguu ucagccucag cccgugcaac      420

cacagccuca ccagccccug cagccacaau cccccaugca uccuauccag ccacuucugc      480

cgcagccccc uuugccaccc auguucucua ugcagucgcu ccugccugac cugccacucg      540

aagccuggcc cgcaacagau aagacuaaaa gggaggaagu agacugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  2903
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt3)

<400>  2903
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggaucuu cuuugccugc cugcucgggg cuagccuugc aaugccccug ccuccacacc      120

cgggacaucc cgguuacauu aacuucuccu augagguguu gacaccuuua aagugguacc      180

agaauaugau aagacaccca uauacuucuu acggcuauga acccauggga ggguggcugc      240

aucaccaaau cauuccuguc guuucacagc agacgccaca gagucaugcc cuacaacccc      300

accaccauau cccuauggug ccagcgcagc agccgggcau uccccagcaa ccuaugaugc      360

cacuccccgg ucagcacagc augaccccua cacagcauca ccagccaaac cugccccuuc      420

cggcucaaca gccuuuucag ccccaaccag uacagccuca gccccaccag ccacugcaac      480

cccagucccc uaugcaucca auccagccgu ugcuccccca gccuccacug cccccuaugu      540

ucucuaugca aucgcugcuc ccagacuuac cccuggaggc cuggccggca acugauaaaa      600

ccaagaggga agagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  2904
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt3)

<400>  2904
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuugggg cugcauuuag caugccccug ccuccacacc      120

cgggacaucc cgguuacauu aacuucuccu augagguguu gacaccuuua aagugguacc      180

agaauaugau aagacaccca ucucugcuac ccgaccuccc ucuggaagcc uggccagcga      240

cugauaaaac gaagagggag gaagucgacu gaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  2905
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt3)

<400>  2905
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuugggg cugcauuuag caugccccug ccuccacacc      120

cgggacaucc cgguuacauu aacuucuccu augaggacuu guacuuagaa gccauaagaa      180

ucgauaggac agcguuugug cugacuccuc uaaaguggua ucagaauaug auucggcacc      240

cauacacguc uuauggcuac gagcccaugg gaggguggcu ccaucaccaa aucauuccug      300

ucguuucaca gcagacccca cagagucaug cucugcaacc ccaccaccau aucccuaugg      360

ugccagccca gcagccgggc auaccccagc aaccuaugau gccacuuccc ggucagcaca      420

gcaugacacc uacucagcau caccagccaa accugcccuu gccggcacaa cagccuuucc      480

agccccaacc aguacagccu cagccccacc agccacucca accccagucc ccuaugcauc      540

caauccagcc gcugcugccc cagccuccau uacccccuau guuuucuaug caaucgcucc      600

ugccagaccu ucccuuggaa gccuggccgg cuaccgauaa aacaaagcgc gaggaagugg      660

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  2906
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt3)

<400>  2906
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuugggg cugcauuuag caugccccug ccuccacacc      120

cgggacaucc cgguuacauu aacuucuccu augagguguu gacaccuuua aagugguacc      180

agaauaugau aagacaccca acuccccaau cucaugcccu gcagccucac caucacaucc      240

caaugguccc cgcgcagcag ccuggcauuc cacaacagcc gaugaugccc cuaccugggc      300

agcacucaau gacgccaacc cagcaucacc aacccaaccu cccucugcca gcucagcagc      360

ccuuucagcc gcaaccuguu cagccccagc cacaucaacc ucuucagccc cagaguccaa      420

ugcaccccau ccagccucug uugccacaac cgccccuccc uccaauguuc agcaugcagu      480

cccugcugcc cgaccucccu uuagaagccu ggccagcaac agauaaaacu aagagggagg      540

aaguggacug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  2907
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt3)

<400>  2907
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccaca cccgggccau cccggguaca ucaacuucag cuaugaggug cucaccccuc      120

uuaaguggua ccagaauaug auuagacacc cauauacauc cuacggauau gaacccaugg      180

guggcuggcu gcaucaccaa auaaucccug ucguuucuca gcagacucca cagucacaug      240

ccuugcaacc ccaccaccau auuccuaugg ugccagcuca gcagccgggg aucccccagc      300

aaccuaugau gccauuaccc ggacagcaca guaugacgcc uacccagcau caccagccaa      360

accugccccu accggcacaa cagccuuuuc agccccaacc aguacagccu cagccccacc      420

agccacucca accccagagc ccuaugcauc caauucagcc gcugcuuccc cagccuccac      480

ugcccccuau guucuccaug caaucuuugc ucccagaccu gccccuggag gccuggccgg      540

cgacagauaa aacuaagagg gaagaggugg acugaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  2908
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt3)

<400>  2908
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gcguggccag acugccucuc cuucuggggu uguuacugcu accaaggccg ggacggcccc      120

ucgaccuggc ugauuacacc uaugaccuug cagaggaaga ugacagcgag ccucugaacu      180

acaaggaucc augcaaagcc gcggcuuucu ugggugacau cgcccucgau gaagaggacc      240

ugcgcgcauu ucagguccaa caggccguug aucugcgacg ucacacagcu agaaaguccu      300

cuauuaaagc agccgugccc ggcaauacuu caacgccuag uugucagagc accaacgggc      360

agccacaaag gggagcuugc ggccgguggc gcgguagauc caggucucgg cgcgccgcga      420

caucgcgacc cgaaagagua uggccugacg gggugauacc auucgucauc ggaggcaauu      480

uuacuggcuc acagagggca guguuccggc aggccaugcg ucauugggag aagcacaccu      540

guguuacauu ucucgagcgc accgaugaag acagcuauau uguguucacu uacagaccgu      600

gcggguguug caguuauguc ggaaggcggg guggcgggcc ccaggcuauc uccauuggaa      660

agaacuguga uaaguuuggc aucgugguac augaguuagg ucacguugug ggguucuggc      720

augaacacac acgaccugac cgcgacagac acgucucuau agugagggag aauauccaac      780

caggacagga guacaacuuu cugaagaugg aaccccagga gguggaaagc cuuggcgaga      840

ccuaugauuu cgacuccauu augcauuacg cccggaauac guuuucacgc ggcaucuucu      900

uggauacuau ugucccuaaa uacgaaguua acggggugaa gccacccauc ggacagagaa      960

ccaggcugag uaaaggugac auagcacaag cucguaagcu auauaaaugc ccggccugug     1020

gcgagacacu ccaggauagc acugggaauu uuucuucccc ugaguacccc aacggauauu     1080

cagcgcacau gcauugcgua uggcggauua gcgugacccc aggcgaaaag aucauucuga     1140

auuucacaag ucuugaccug uaccgaucua gauuguguug guaugauuac gucgagguga     1200

gggacgguuu cuggcgcaag gccccucucc gggggagauu uugcggcucc aaacugcccg     1260

aaccaaucgu uagcaccgau ucgagguuau ggguggaguu ccgaucuucc ucaaacuggg     1320

ucggaaaggg cuuuuucgca guguaugaag cuaucugcgg gggagacguu aaaaaggauu     1380

acggucacau ucagaguccc aauuacccug acgacuaucg cccaagcaaa guauguauau     1440

ggcggaucca aguguccgag ggcuuucacg ucgggcugac guuccagucu uuugagauug     1500

aacgucauga uagcugcgcc uacgacuauc ucgaggugag agauggacac ucagaaaguu     1560

ccacucuuau cggcagguac ugugguuaug agaagccgga cgauauaaaa agcacaucuu     1620

cacgccugug guugaaguuc gucagugacg ggagcauuaa caaggcuggc uuugccguga     1680

auuucuuuaa agaaguugau gagugcuccc ggcccaacag aggaggcugu gagcagaggu     1740

gccuaaacac ccuggggucu uacaaguguu cgugcgaccc uggauaugaa cucgcaccag     1800

auaaacgacg cugugaggcc gcuugcggug gcuuccugac uaaacuuaau gggagcauca     1860

caucccccgg auggccuaaa gaauacccac ccaacaagaa uuguaucugg cagcuggugg     1920

cgccgaccca auaccggauu ucauugcagu uugacuucuu cgagacggag ggcaacgaug     1980

uaugcaagua ugacuuuguc gaagugagaa guggucucac cgcagauucu aaacugcaug     2040

ggaaguucug cggcagcgag aaaccugaag uuaucacauc ccaguacaau aacaugaggg     2100

uggaguuuaa gucagacaau acugucagca aaaagggauu caaggcccac uuuuucucug     2160

acaaagauga auguuccaag gacaacggcg ggugccagca agauugugug aauaccuuug     2220

gaaguuauga gugccagugu cguagcggcu ucguauuaca ugacaacaaa cacgauugca     2280

aggaggcugg uugugaccac aaagugacau cuacuuccgg gaccauuaca ucaccaaauu     2340

ggcccgauaa guacccuagu aagaaagaau gcaccugggc cauaagcucg acucccggac     2400

aucgcguuaa gcugacguuu auggagaugg acaucgaauc ccagccagag ugugcauaug     2460

aucaccuaga agucuucgac ggccgggaug ccaaagcucc ugugcucggu agauuuugcg     2520

gcucuaagaa acccgagcca gugcuggcca cagggagcag gauguuccuu cgauuuuacu     2580

cagacaacag uguccagcgg aagggauucc aagcauccca ugcgaccgag uguggcgggc     2640

agguucgcgc ugaugugaaa acuaaggacu uguauucuca cgcccaguuc ggagacaaua     2700

acuacccggg cgguguggau ugcgaauggg uaauugucgc agaggaaggg uacggagugg     2760

agcugguuuu ucagaccuuc gaaguggagg aggaaacaga cugcggcuau gauuacaugg     2820

agcucuuuga cgguuaugau agcaccgccc cuagacuggg cagguacugu ggguccggac     2880

ccccagaaga ggucuauuca gcuggcgaca gcgugcuugu uaaguuccac agugaugaca     2940

cuaucacgaa aaagggguuu caucugcggu acacaucuac caaauuccaa gauacuuugc     3000

acucccgaaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  2909
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt3)

<400>  2909
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

ccggcaccag augccugcuc gcuuugcugu ugccccaggu cuuacuggga ggggcagccg      120

gucuaguucc ugagcucggc aggcggaagu ucgcggcugc cagcuccggg cgcccaucuu      180

cacaaccgag ugacgaagug cugagcgagu uugaacuucg acuguugucc auguucggac      240

ucaaacagcg ucccacaccu ucuagagaug caguagugcc acccuacaug cuggaccugu      300

auaggcggca cucgggccag ccugguucac cagcccccga ucaucgccuc gagagagcug      360

caagcagggc caacacuguc cggaguuuuc accaugaaga guccuuagag gaacugccug      420

agacgucugg gaagaccaca cgccgauucu uuuucaaucu uagcuccauc ccaacugaag      480

aguuuauuac cucagcugag cuucaggugu ucagagaaca aaugcaggac gcccugggaa      540

acaauaguag cuuucaccau aggauaaaca ucuacgagau uaucaaaccg gcgacagcaa      600

auucuaaguu ccccguuacc cggcuacucg auacucgucu ggugaaccag aaugccuccc      660

gcugggaauc auuugacguc accccugcug ugaugagaug gacagcccag ggccacgcaa      720

accacggcuu cguaguugag guggcucauc uugaagagaa acaagggguc agcaagaggc      780

acgugcggau uagucgaucu cugcaucagg augagcacuc cuggagccag auccgcccau      840

ugcucgugac guuuggacac gacgguaagg gccauccccu gcacaaaaga gaaaagaggc      900

aggccaaaca uaagcaacgg aaacgcuuaa agucgucuug uaagagacac ccucuguaug      960

ucgauuucuc cgacguuggg uggaaugauu ggauaguggc gccacccgga uaccaugccu     1020

ucuauugcca cggcgagugu ccguuuccuc ucgcagacca ccuuaacuca acuaaucaug     1080

cuaucguaca gacccuggug aacaguguca auagcaaaau ucccaaggcc ugcugugugc     1140

caacagaauu guccgcuauc ucuaugcuau accuggauga gaacgaaaaa guugugcuca     1200

agaauuauca ggacaugguc guggaggguu gcggguguag gugaggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  2910
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt3)

<400>  2910
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaucc       60

ccggcaacag aaugcugaug gugguccucc uuugccaggu ucuguuaggg ggagccagcc      120

acgcuuccuu gauuccugag accgguaaga aaaagguggc agaaauacaa ggccaugccg      180

ggggaaggcg gucuggccag ucacacgagc ugcuacgcga cuucgaagcg acacuccugc      240

agauguuugg ucuucgacgu agaccacagc cgaguaaaag cgcuguaauc cccgauuaca      300

ugagggaccu guaucgguug caauccgggg aggaagagga ggaacagauu cauucuacug      360

gacucgagua cccugaacgc ccagccucga gagcaaauac ggugagguca uuccaccaug      420

aggagcaccu ggaaaacauc cccggcacca gcgagaauag ugccuuucgg uuccuguuua      480

accucuccuc uauuccugaa aaugagguca ucagcuccgc ugaauuacgc cuguuccgag      540

aacaggugga ucagggccca gacugggaga gaggguuuca caggauaaac aucuaugagg      600

uuaugaagcc cccugcagag guggucccag gacaucuuau uacacgguug cuggauacuc      660

gucuagugca ccauaaugua acccgcuggg aaacauucga cguuucaccg gccgugcuca      720

gauggaccag ggagaaacaa cccaacuacg gucuggcuau cgaagucacu caccuucacc      780

agacacggac ccaucagggc cagcacgugc gaauuagucg cagccugccu caagggucug      840

gaaauugggc ccaguugaga ccacuccugg ugacguuugg ccaugauggu agggggcacg      900

cguuaacucg gcgcagaagg gcaaagcguu cccccaagca ucacucacag cgggcccgaa      960

agaaaaacaa aaauuguaga aggcacagcc uguaugucga cuucagugau guuggaugga     1020

acgacuggau cguggcuccu ccaggcuacc aagccuuuua uugccauggc gauugucccu     1080

ucccgcucgc agaccaccuu aauucuacca accaugcuau aguacagaca cuggucaauu     1140

ccgugaacag cucgauuccu aaggccugcu gugugcccac ugaguugucu gcgaucucca     1200

ugcuauaccu ggaugaguac gacaaaguug ugcucaagaa cuaucaggaa auggucgugg     1260

aggggugcgg augucgcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  2911
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt3)

<400>  2911
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gccuagggag aagggcccag uggcucugcu gguggugggg acuucugugu agcugcugug      120

guccuccacc guugcggccc ccuuuaccag cugcagccgc ggcugccgca ggcgggcaac      180

ugcuaggaga cggcgguucc cccgggcgca ccgagcagcc uccacccucu ccucagucaa      240

guagcggauu ccucuaccga cgucugaaga cacaggagaa aagagaaaug caaaaggaaa      300

uccuuuccgu gcugggcuug ccacacaggc cgcggccccu ccauggccug cagcagccuc      360

agccacccgc ccugcgccaa caggaggaac agcagcaaca gcagcaacuc ccuagagggg      420

agccaccccc gggaagguua aaaucugcuc cucuguuuau gcuugauuug uauaacgcac      480

ugucggccga caaugaugag gacggugcuu cagaaggcga gcggcagcag agcuggcccc      540

acgaagccgc gaguuccucu cagcgccgac aaccaccucc cggggcagcc cauccacuaa      600

acagaaagag ccuccuggcu cccggauccg gcucaggugg ggccaguccu cuuacuagcg      660

cacaggauuc ugcuuuccug aaugacgccg auauggucau guccuuuguu aacuuggugg      720

aguacgacaa agaguucuca ccaaggcagc ggcaccauaa ggaauuuaag uucaaucuca      780

gccagauucc ggagggagaa guagugacgg cggccgaguu ucguauauau aaagauugcg      840

ucaugggcag uuucaagaac caaaccuuuc ugaucucuau uuaccaggug uuacaggaac      900

accagcaccg cgacuccgau cuguuccucc uugacacaag aguugugugg gcaagcgagg      960

agggcuggcu ggaauuugau aucacugcua ccucgaauuu gugggucgug acaccccaac     1020

auaacauggg gcuacagcug ucuguaguua ccagggacgg agugcacguc cauccucggg     1080

ccgcuggucu cgugggccga gacgggccau augauaaaca gcccuucaug guggccuuuu     1140

ucaaggucuc cgagguucac gugcgcacua caagaucagc aaguagcagg cggcgccagc     1200

aauccagaaa uaggucuacc cagagccagg acguagcccg ugugucaagu gcuuccgauu     1260

acaacagcuc ugaacugaaa acggcguguc ggaagcacga gcuuuauguc ucauuccaag     1320

accugggaug gcaggauugg auuaucgcac cuaagggcua cgccgcuaau uacugcgacg     1380

gugaauguag uuuuccauug aacgcccaua ugaaugcaac uaaccacgcc auagugcaga     1440

cccucguuca ucugaugaau cccgaguaug ugccgaaacc uugcugugcu ccaacaaagu     1500

uaaacgccau cagcguccug uacuucgaug acaacuccaa ugugauucug aaaaaguauc     1560

gaaacauggu aguuagagca ugcggguguc acugaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  2912
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt3)

<400>  2912
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

ugagaagccu gagggccgcu gcaccccauu ccuucgucgc ccucugggcg ccucuuuuuc      120

uguugcgguc ugcuuuagcc gacuucucac uggauaacga gguucacagu agcuuuaucc      180

aucgccgacu acguucccag gaaagaaggg agaugcaacg ggaaauucuc ucuauacugg      240

gccuuccaca ccgcccgaga ccccaucugc aggggaagca caauucggca ccuauguuca      300

uguuggaccu cuacaacgcc auggcugugg aggaaggagg uggcccaggg ggacagggcu      360

uuucauaucc cuacaaagca guauucagca cccagggucc uccacuggcc agucugcaag      420

auucccacuu ucucacagac gcugauaugg ugaugucuuu cgucaauuua guggagcaug      480

acaaggaguu uuuccacccc agguaucauc accgggaauu ucgcuucgau cugagcaaaa      540

ucccugaggg ggaagccguu acugcggcag aguuucgaau uuacaaggac uauaucagag      600

agagguucga uaacgaaacg uuccggauuu ccguguacca gguccuucag gagcacuugg      660

gacgugaauc agaccuguuu cuacucgaua gucgcacccu gugggccagc gaggaaggcu      720

ggcuuguguu cgacaucaca gcuacuucua aucauugggu aguuaaccca agacacaauc      780

ugggcuugca gcucuccgug gagacccugg augggcaauc aauaaacccg aaauuagccg      840

gacugaucgg uaggcauggc ccccagaaua agcagccuuu uauggucgca uucuuuaagg      900

cuacagaggu gcacuuccgg agcauucgaa guaccggguc uaaacagcgc ucccaaaaca      960

gaagcaagac ucccaaaaau caggaagccc ucaggauggc gaacguggcc gaaaauucgu     1020

cuuccgacca gcggcaagca ugcaagaaac augagcuuua ugucucauuu cgcgaccugg     1080

gauggcagga uuggaucauu gcuccagagg gcuacgccgc uuacuauugu gaaggugagu     1140

gcgccuuccc uuugaacagu uacaugaaug caacaaacca cgccaucguu cagacccuag     1200

ugcacuuuau aaacccagag acgguaccca agccguguug cgcuccuacu cagcugaaug     1260

cgauuagcgu gcucuauuuc gacgauuccu cuaacgucau ccugaagaaa uacagaaaua     1320

uggugguuag ggcauguggg ugccauugag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  2913
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt3)

<400>  2913
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagg       60

ccagcgcugc acugcucugc cuucuguuga ccgccgcggc uuucucuccc cagggcuuag      120

cccaaccugu ggggaucaac acauccacua cguguugcua cagauuuauu aauaaaaaga      180

uaccaaaaca gaggcuggag ucauaucggc gcaccacaag uagccacugu ccgcgagaag      240

cagucaucuu caagacuaaa cuagacaagg agauuugcgc cgaucccacc cagaaguggg      300

uucaggacuu uaugaaacau cucgauaaga aaacacaaac cccuaagcug ugaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  2914
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt3)

<400>  2914
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugc       60

ucacccuuau cauucuguug cccgugguca gcaaguucuc cuuuguuucu uuaucagccc      120

cucagcacug gaguugccca gagggcacac uggcugggaa cggaaauagc acuugugugg      180

guccggcacc cuuccuaaua uuuucccaug gcaacucuau cuucagaauu gacacggaag      240

ggaccaauua cgagcaacuc guaguggacg ccggagucuc ggugaucaug gacuuucacu      300

auaacgaaaa gaggauuuac uggguugauc uggagcggca gcuucugcag cgcguguucu      360

ugaauggcuc acgacaggaa cgugucugca acaucgagaa gaaugugagc gguauggcga      420

uaaacuggau caaugaggaa guaauuugga guaaccaaca ggaggggauc auuacaguua      480

cugacaugaa aggaaauaac ucccauaucc uccugucugc ucugaaguau ccugccaaug      540

uggcagucga uccaguggaa agauuuauau ucuggagcuc cgagguggcc ggcucacucu      600

acagggcuga cuuagauggc gucgggguua aagcacugcu ugagaccagu gaaaagauua      660

cagccgugag cuuggacgua cuggauaagc ggcuauuuug gauccaguau aaccgcgagg      720

gaucuaauuc ccucauuugu ucaugcgacu acgauggugg cagcgugcac aucaguaaac      780

aucccaccca gcacaaccug uucgcuaugu cucuuuuugg ggacagaauc uucuauucca      840

cuuggaagau gaaaacaauu uggauagcca acaagcacac cggaaaagau auggucagga      900

ucaaucugca uagcucguuu gugccuuugg gcgaacucaa gguugugcac ccacuggcgc      960

aacccaaggc agaggacgac acgugggaac cugagcagaa auuauguaag cugcggaaag     1020

guaacugcuc auccacuguc ugugggcagg aucuccaguc acaucuuugc augugugccg     1080

agggauacgc ucugagucgc gaccgaaagu acugcgaaga ugugaaugag ugugccuucu     1140

ggaaccacgg cugcaccuug ggcugcaaaa auacaccagg gagcuauuac uguacuugcc     1200

cgguaggauu cguucuacug cccgacggua agagauguca ccaacucgug uccugcccua     1260

ggaacgucuc ugaauguagc caugauugcg ugcugaccuc agagggccca cuuuguuuuu     1320

gccccgaagg gaguguccug gagcgggacg gaaaaacaug uuccggcugc agcucuccug     1380

auaauggugg guguucacag uugugcgugc cacucagucc cguuagcugg gagugcgacu     1440

guuucccggg cuaugaucug caguuagacg aaaaguccug cgcagcuucu ggaccucaac     1500

ccuuucugcu auucgccaac ucgcaggaua uucgucacau gcauuuugac ggcaccgacu     1560

acgggacgcu ccugagccag cagaugggaa ugguguaugc gcuugaucac gacccaguag     1620

agaauaagau cuacuucgcc cauacugcau ugaaauggau agaacgcgcu aacauggaug     1680

guucccaaag agagaggcug auugaagagg gcgucgacgu gccugagggg cucgccguug     1740

auuggaucgg acggcgauuu uauuggacag accgcggcaa gucacugauc gguagaagug     1800

aucuuaaugg gaaaaggucu aagauuauca ccaaagaaaa cauuagccag ccccggggca     1860

uagcugugca cccaauggcc aagcgccugu ucuggacuga cacaggaauc aaucccagaa     1920

uugaguccuc uagcuugcag ggccucggga ggcuggucau cgcaucuucc gauuuaaucu     1980

ggccuagugg aauuaccaua gacuuucuga cggauaagcu auacuggugu gacgccaaac     2040

agagcgugau cgaaauggcu aaccucgaug guucuaagcg ucggcgacug acccaaaaug     2100

acguaggcca cccauucgcg guggcaguuu uugaggacua cgucugguuc uccgauuggg     2160

ccaugccguc agugaugaga gugaacaaaa ggacagggaa ggaccgcguc cggcuucagg     2220

gaaguauguu gaaacccagc ucgcugguug uggugcaucc ucucgcuaag ccaggcgccg     2280

aucccugccu guaucagaac ggugggugug agcacauuug caagaaaaga uuaggcacug     2340

caugguguuc cugcagggaa ggauuuauga aggccucuga cggcaaaacc ugucuggcuc     2400

uugaugggca ucaguugcuc gccggaggcg agguagaccu gaagaaucaa gucacaccuc     2460

uagauauccu gagcaaaacu cgcgugucag aagacaacau uaccgagagu cagcacaugc     2520

ucguugcaga aaucauggug uccgaucagg acgauugcgc gccagucggu uguucuaugu     2580

acgcucgaug cauaagcgag ggggaggacg ccacaugcca gugucugaag ggauucgcag     2640

gcgaugguaa acuuugcucc gacaucgacg aaugugagau gggcgugccc guuugcccgc     2700

cugccucaag caaauguauu aauaccgaag ggggauaugu gugccggugu agugagggcu     2760

accaagggga uggaauccac ugcuuggaca uugaugaaug ucagcugggc gagcauucuu     2820

gcggugagaa cgcuuccugu acuaauacgg aagggggaua uacaugcaug ugcgccggcc     2880

guuuaagcga gccaggucuc aucugucccg acucgacccc ucccccacac cugagagaag     2940

augaccauca cuacucagua aggaacucug auagugagug cccucuuucc caugacggcu     3000

auugucugca cgaugggguc ugcauguaca uagaagcauu ggacaaguac gcuuguaauu     3060

gcgugguggg auauauuggc gagcgcuguc aguaccggga ucucaaaugg ugggagcuga     3120

gacacgccgg gcauggacaa cagcagaagg ucaucguugu ggcgguaugc guggucgugc     3180

uaguuaugcu gcuccugcuu agcuuguggg gcgcccacua uuacaggacu cagaaacugu     3240

uaucuaagaa ccccaaaaau ccauaugaag agagcucccg agacgugcgc ucacggagac     3300

cggcugacac cgaagauggu augaguagcu guccucaacc cugguucguc gugauuaagg     3360

agcaucagga ccucaagaac gggggacagc caguugcagg cgaggauggu caggccgcug     3420

acggcucuau gcaacccaca uccuggaggc aggaaccuca gcugugcggg augggaaccg     3480

agcagggcug uuggauccca gugucaagug auaaagggag cugcccccaa gucauggaac     3540

guuccuuuca caugccuucu uacggaacuc agacacuuga gggcggugua gaaaagccgc     3600

auucgcugcu aagcgccaau ccacucuggc agcaacgcgc acuggauccc ccucaccaga     3660

uggaguugac gcagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  2915
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt3)

<400>  2915
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

ccggcagaag gauggagaug cugugcgcug ggcgggugcc cgcacuccuu cuguguuugg      120

gauuccacuu acugcaggcc guccuaagca caacuguuau cccuuccugc auuccaggug      180

aaucuucaga caacuguacg gcgcucgugc aaaccgagga uaauccgcgc guagcucagg      240

ugaguauaac aaagugcagc uccgacauga acggcuacug ucugcauggg cagugcaucu      300

aucuugucga uaugucucag aauuacuguc gaugcgaagu gggauauacu ggcguucguu      360

gugagcacuu uuuccugacc gugcaucaac ccuugucgaa agaauacguc gcccucacag      420

ugauucugau cauucuguuu cucaucaccg uaguugguuc aacuuauuac uucugcagau      480

gguauaggaa ccgcaagagc aaagagccua agaaagagua cgaacgggug acaagugggg      540

acccagaguu accccagguc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  2916
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt3)

<400>  2916
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

agggcgaaau caccacauuc acugcucuga cggagaaguu uaaccuuccc ccugggaauu      120

acaaaaagcc aaaacuccug uauugcagca acggagguca cuucuugaga auuuuaccgg      180

acggcaccgu ggaugggaca agggaccggu ccgaucagca uauacaacug cagcuaucug      240

cagaaucagu cggagagguu uacaucaaga guacugaaac cggccaguau cucgccaugg      300

acacagaugg ucugcuuuac gggagccaga cccccaauga ggagugucug uuuuuggaac      360

gccucgagga aaaccacuau aauacuuaca uuuccaaaaa gcaugcggag aagaacuggu      420

ucgugggacu gaaaaagaau ggcucuugca aacgaggccc ucguacacac uaugggcaaa      480

aggcuauccu guuucuccca uuacccguau cgucagacug aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  2917
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt3)

<400>  2917
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

gcgucggggg aggugacguu gaggauguga cccccagacc uggcgggugc cagaucagcg      120

gaaggggcgc ccgggguugu aacgggauuc caggagcugc agccugggaa gcggcucugc      180

cgcgccgacg ucccagaagg cacccuuccg uaaauccacg gucucgcgcc gcaggcucac      240

ccagaacaag gggccggcgc acugaggaac gaccuagugg gagcagacuc ggagacaggg      300

gucggggccg ugcccuucca gggggacgcc ugggcgguag agggagggga cgggcucccg      360

agcgaguggg cggccgcggg agaggaaggg guacggcagc cccucgggcu gccccagcgg      420

cacgcggcuc cagaccgggg cccgccggaa ccauggcugc cggcucuaua acaacuuugc      480

cugcauuacc agaagauggu gggucgggcg cuuuuccccc uggacauuuc aaggacccaa      540

aaaggcugua cugcaagaac ggcggguucu uucuacguau ccaccccgau ggacgggucg      600

acggugugcg agagaaauca gauccgcaua uuaagcucca acugcaggcc gaggaaagag      660

gcguugugag caucaaaggg gucugugcga auagguaucu ugccaugaag gaggacggac      720

gccuguuggc aaguaagugc gugaccgaug aauguuucuu uuucgagcgg cucgagucca      780

acaauuacaa cacauauaga ucuaggaaau acaccagcug guauguagcu cugaagcgca      840

cuggccagua caaacugggu uccaagacag ggccuggcca gaaagccauu cucuuuuuac      900

ccaugucagc uaagaguuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  2918
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt3)

<400>  2918
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aguggauccu gaccuggauu cuccccacac uucuguacag aagcugcuuc cauauaaucu      120

guuugguggg cacuauuucc uuagccugca acgacaugac gccugagcag auggcuacca      180

augucaacug uucuucacca gaaaggcaca cacggaguua ugauuacaug gagggaggag      240

acauccgcgu ucgacgucug uuuugcagaa cucaauggua ucuaaggauu gauaaacggg      300

guaaggugaa aggcacccag gaaaugaaga auaacuacaa uaucauggag auacgcacag      360

uagcaguggg gaucgucgcc auuaaaggag uggaaagcga guucuaucuc gcgaugaaca      420

aggagggcaa gcuguacgcu aaaaaggaau guaaugagga cugcaacuuu aaagaacuua      480

uccuggagaa ucauuauaac accuacgccu ccgcaaagug gacucacaau gguggggaga      540

uguucguugc cuugaaccag aaagggauuc cggugagagg caagaagacc aaaaaggaac      600

agaaaacagc ucauuuucuc cccauggcaa ucacgugagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  2919
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt3)

<400>  2919
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ugcuccccag cgugguccuu aaacuguucu uggccgcugu uuuauccgca cuggugaccg      120

gcgagucucu agaaagacuc aggcgggggc uggccgcggg aacaucaaac ccugacccac      180

cgacuguaag uacggaucag cuucugcccu uggguggcgg gcgcgaccga aaggugcgug      240

aucuccaaga ggcugaccug gaucugcuca gagucaccuu aagcuccaaa ccucaggccc      300

uggcaacacc aaauaaggag gaacacggaa aaaggaagaa gaaaggcaag ggucuuggga      360

aaaagcggga ccccugcuug cgcaaauaca aggauuuuug uauccaugga gaaugcaagu      420

augugaaaga gcugagagcc ccuucuugua uuugccaccc aggcuaccau ggcgagaggu      480

gucacgggcu aucgcucccc guugaaaacc ggcuguauac uuacgaccau accacaauac      540

uugcuguggu cgcaguggua cugucaagcg uuugcuugcu cgugaucguc ggacuguuaa      600

uguuccgcua ucaccgaaga gguggcuacg auguggagaa ugaagagaag gugaaacugg      660

ggaugaccaa cagucacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  2920
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt3)

<400>  2920
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ugaccaagcu gcuccccgcc cuucuguugc agcacgucuu acugcaucua cuccugcuuc      120

cuaucgcuau uccauacgca gagggccaaa gaaaaaggcg gaacacaaua cacgaguuca      180

agaaaagcgc caagacuacg cugaucaaaa uugacccggc guugaagauc aagaccaaaa      240

agguuaauac agcugaucag ugcgccaacc gcuguacucg aaauaaaggg cuccccuuua      300

ccugcaaggc auucguguuu gacaaagccc guaagcagug ucugugguuc ccuuuuaacu      360

ccaugucuuc aggaguaaag aaagaguucg gucaugaauu ugaucuguau gagaauaagg      420

acuacauuag aaacugcauc auaggcaaag ggaggaguua uaagggaaca gugagcauca      480

ccaaauccgg cauuaagugu cagccauggu cuucgaugau cccccacgaa cauucauucc      540

ucccuagcag uuaccggggu aaagauuuac aagagaauua uugccgcaac ccaagagggg      600

aggaaggagg ccccuggugu uuuacuucca auccugaggu cagguacgaa gugugcgaca      660

uuccacagug uucugagguu gagugcauga cauguaacgg cgaaagcuau cgggggcuga      720

uggaucacac cgaguccgga aagaucugcc agcgcuggga ccaccagacg ccgcaucgac      780

acaaguuccu ucccgaaaga uacccugaua aagguuuuga cgauaauuac ugcaggaacc      840

cagacggcca accccggccu ugguguuaua cuuuggaucc acauacccgu ugggaauacu      900

gcgcuauaaa gacaugugca gacaauacua ugaacgacac cgaugugccc cuggaaacaa      960

ccgagugcau ucaggggcag ggagagggcu aucgcgguac ggucaauacu aucuggaacg     1020

ggauuccgug ucagagaugg gacucacaau acccucacga acacgauaug acacccgaga     1080

acuucaaaug caaggaccua agggaaaauu auugucggaa cccagaugga agugagagcc     1140

cuuggugcuu uaccacugac cccaauaucc gagugggcua cuguucucag aucccaaacu     1200

gcgauauguc ccauggccag gacuguuauc gcgggaaugg uaaaaacuac augggaaauc     1260

ucucacaaac aagaagcggc cugaccugca guauguggga uaagaacaug gaagaccuuc     1320

acaggcauau uuucugggag cccgaugccu cuaagcugaa ugagaacuac ugccggaauc     1380

cugacgacga ugcucacggg ccaugguguu auacgggaaa cccguugaua cccugggacu     1440

acugcccuau cucccgcugu gaaggcgaua ccacaccaac uauuguaaau cucgaccauc     1500

ccguuaucag cugcgccaaa accaagcagc ugagaguggu caacgguaua ccuacaagga     1560

cuaauauugg guggauggug ucguuacguu aucggaacaa acacaucugu ggcggaucuc     1620

ugaucaagga guccugggug cucaccgcgc gacagugcuu cccaucaaga gaucuuaaag     1680

acuacgaagc auggcugggc auucacgaug uccaugggag gggagacgag aaguguaagc     1740

agguuuugaa cgugagucag cuaguauaug gucccgaagg cagcgaucug gugcucauga     1800

aacuggcccg cccggcuguc cuugacgauu uuguguccac aaucgaccug ccuaauuacg     1860

ggugcaccau uccagagaag acuucuugua gcguuuaugg auggggcuac acggguuuga     1920

uaaacuacga ugggcuccug cggguggccc acuuauauau caugggcaau gagaaaugcu     1980

cacaacauca cagaggaaag gucacacuga acgaaaguga gauuugugca ggcgcugaga     2040

aaaucggguc cggacccugc gaaggugacu acggcgggcc ucuagugugc gagcagcaca     2100

agaugaggau gguacucgga guuaucgugc ccggccgcgg uugugccauu ccaaaucgac     2160

cugggauauu cguccgggug gcguauuacg ccaaguggau ccauaaaauu auccugaccu     2220

auaagguccc ccagagcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  2921
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt3)

<400>  2921
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aggcugcagc caucggcauu gaccugggga ccacauacag cugcguggga gucuuccagc      120

acgguaaagu ugagauaauc gcgaacgauc aaggcaauag aacuacgccc uccuaugugg      180

cuuuuaccga cacagaaagg cucauugggg augccgcaaa gaaccaggua gcccuuaauc      240

cucagaacac uguguucgac gcuaaacggc ugaucggacg caaguuuggc gauccagucg      300

ugcagucuga caugaaacau uggccguucc aaguuauuaa ugauggugac aagcccaagg      360

ugcaggucuc auacaaaggg gagaccaagg cauuuuaucc ugaagagauc aguagcaugg      420

uguugacaaa aaugaaggaa auagccgagg cuuacuuagg auauccagua accaacgccg      480

uuaucacugu gcccgcguac uucaaugauu cccagcgaca ggcaacaaaa gacgccggcg      540

ucauugcugg ccugaacgug cuacguauca uuaaugagcc uaccgccgca gcuaucgccu      600

augggcucga uagaacggga aagggugaaa ggaacgugcu gauauuugac cuuggcgggg      660

gaacuuucga ugucucuauu cugaccaucg acgacggcau uuuugagguu aaggcgacag      720

ccggugauac ucaccuuggg ggagaagacu ucgauaaucg gcucgugaac cauuuuguag      780

aggaguucaa acgcaagcac aaaaaggaca ucucgcaaaa uaaaagagca gugaggcggc      840

ugcgcaccgc uugugaacga gccaagagaa cacugucaag caguacccag gcuucccucg      900

agaucgauuc uuuauuugaa ggcauugacu ucuacacgag cauaacuagg gcccgguucg      960

aggaacugug cuccgaucuu uuucguucaa cauuggagcc agucgagaaa gcacugcgcg     1020

acgccaagcu agauaaggcu cagauccaug accucgugcu gguuggcggg aguacccgga     1080

uucccaaagu gcagaaguug cugcaagauu ucuuuaacgg aagggacuug aauaaaagca     1140

ucaacccuga cgaagcgguc gcauacggug ccgcugugca ggccgcaaua cucaugggcg     1200

auaagucuga gaacguacag gaccuguuac ugcucgaugu ugccccacuu ucccuggggu     1260

uggaaacugc uggaggcgug augacagccc uaauuaaaag aaauucaacc aucccgacga     1320

agcaaaccca gaucuucaca acuuauagcg acaaccagcc cgguguccug auucaggugu     1380

acgaggggga acgagcaaug accaaggaua auaaccuccu gggccgcuuu gagcuuagug     1440

gaaucccucc agcgcccaga ggcgucccuc aaauugaggu gacauucgac auagaugcua     1500

augggauccu gaacguuacu gccaccgaca aaucuacagg aaaggcaaau aaaauuacca     1560

ucacuaacga uaaggguagg uuguccaaag aagagaucga acggauggug caggaggccg     1620

aaaaguauaa ggcugaggac gagguacagc gcgaaagagu cagcgccaaa aaugcacucg     1680

agucguacgc uuuuaacaug aagucugccg uggaagauga gggccugaaa gggaagauuu     1740

ccgaggcgga caaaaagaag guuuuagaua aaugucagga agugauauca uggcuggacg     1800

ccaauacgcu agcugagaag gacgaguucg aacacaaaag gaaggaacuc gagcaagucu     1860

gcaacccaau cauuagugga cuguaucagg gcgccggugg gcccggcccg ggaggcuuug     1920

gggcacaggg accuaaaggu ggcagcgggu ccggacccac aaucgaggaa guggauugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  2922
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt3)

<400>  2922
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aggcugcagc caucggcauu gaccugggga ccacauacag cugcguggga gucuuccagc      120

acgguaaagu ugagauaauc gcgaacgauc aaggcaauag aacuacgccc uccuaugugg      180

cuuuuaccga cacagaaagg cucauugggg augccgcaaa gaaccaggua gcccuuaauc      240

cucagaacac uguguucgac gcuaaacggc ugaucggacg caaguuuggc gauccagucg      300

ugcagucuga caugaaacau uggccguucc aaguuauuaa ugauggugac aagcccaagg      360

ugcaggucuc auacaaaggg gagaccaagg cauuuuaucc ugaagagauc aguagcaugg      420

uguugacaaa aaugaaggaa auagccgagg cuuacuuagg auauccagua accaacgccg      480

uuaucacugu gcccgcguac uucaaugauu cccagcgaca ggcaacaaaa gacgccggcg      540

ucauugcugg ccugaacgug cuacguauca uuaaugagcc uaccgccgca gcuaucgccu      600

augggcucga uagaacggga aagggugaaa ggaacgugcu gauauuugac cuuggcgggg      660

gaacuuucga ugucucuauu cugaccaucg acgacggcau uuuugagguu aaggcgacag      720

ccggugauac ucaccuuggg ggagaagacu ucgauaaucg gcucgugaac cauuuuguag      780

aggaguucaa acgcaagcac aaaaaggaca ucucgcaaaa uaaaagagca gugaggcggc      840

ugcgcaccgc uugugaacga gccaagagaa cacugucaag caguacccag gcuucccucg      900

agaucgauuc uuuauuugaa ggcauugacu ucuacacgag cauaacuagg gcccgguucg      960

aggaacugug cuccgaucuu uuucguucaa cauuggagcc agucgagaaa gcacugcgcg     1020

acgccaagcu agauaaggcu cagauccaug accucgugcu gguuggcggg aguacccgga     1080

uucccaaagu gcagaaguug cugcaagauu ucuuuaacgg aagggacuug aauaaaagca     1140

ucaacccuga cgaagcgguc gcauacggug ccgcugugca ggccgcaaua cucaugggcg     1200

auaagucuga gaacguacag gaccuguuac ugcucgaugu ugccccacuu ucccuggggu     1260

uggaaacugc uggaggcgug augacagccc uaauuaaaag aaauucaacc aucccgacga     1320

agcaaaccca gaucuucaca acuuauagcg acaaccagcc cgguguccug auucaggugu     1380

acgaggggga acgagcaaug accaaggaua auaaccuccu gggccgcuuu gagcuuagug     1440

gaaucccucc agcgcccaga ggcgucccuc aaauugaggu gacauucgac auagaugcua     1500

augggauccu gaacguuacu gccaccgaca aaucuacagg aaaggcaaau aaaauuacca     1560

ucacuaacga uaaggguagg uuguccaaag aagagaucga acggauggug caggaggccg     1620

aaaaguauaa ggcugaggac gagguacagc gcgaaagagu cagcgccaaa aaugcacucg     1680

agucguacgc uuuuaacaug aagucugccg uggaagauga gggccugaaa gggaagauuu     1740

ccgaggcgga caaaaagaag guuuuagaua aaugucagga agugauauca uggcuggacg     1800

ccaauacgcu agcugagaag gacgaguucg aacacaaaag gaaggaacuc gagcaagucu     1860

gcaacccaau cauuagugga cuguaucagg gcgccggugg gcccggcccg ggaggcuuug     1920

gggcacaggg accuaaaggu ggcagcgggu ccggacccac aaucgaggaa guggauugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  2923
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt3)

<400>  2923
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

ccgcuaaggg caucgcaauu gggauagacc ugggaacaac uuacagcugc gugggugucu      120

uccagcacgg caaaguugag aucauugcca acgaucaagg gaauagaacg acccccuccu      180

auguggcguu uacagacacu gaaaggcuca ucggagaugc ugccaagaac cagguagcaa      240

ugaauccuca gaacaccgug uucgacgcca aacggcuuau uggccgcaag uuuaaugauc      300

cagucgugca ggcugacaug aaacuguggc cguuccaagu uaucaacgag ggugggaagc      360

ccaagguguu ggucucuuac aaaggagaaa auaaggcauu uuauccugag gaaauaucaa      420

guaugguguu aacaaaacug aaggagaccg ccgaggcuuu ccuaggccau ccaguaacua      480

acgccguuau cacagugccc gcguacuuua augauagcca gcgacaggca accaaagacg      540

ccggcgucau ugcugggcuc aacgugcugc guaucauuaa ugaaccuacg gccgcagcua      600

ucgccuaugg acuugauaag gguggccagg gggagagaca cgugcugaua uucgacuugg      660

gaggcgguac uuuugauguc uccauucuca ccaucgacga ugggauuuuc gaaguuaagg      720

cgacagccgg agacacucau cugggcggcg aggacuuuga uaacaggcug gugucucacu      780

ucguagagga auuuaaacgg aagcauaaaa aggacaucuc gcaaaauaaa cgcgcaguga      840

gaaggcuccg gaccgcuugu gagcgcgcca agcgaacauu aucaagcagu acccaggcua      900

accuggaaau cgauucccuu uacgagggga uugacuucua uacgucuaua acuagagcca      960

gguucgaaga guugugcgca gaucuguuuc ggggaacacu agagccaguc gaaaaagccc     1020

uccgugacgc uaagauggau aaggcgaaaa uccacgacau ugugcugguu gguggcagca     1080

cccgcauccc caaggugcag agacuucugc aggauuacuu caaugggagg gacuugaaca     1140

aauccauaaa cccugaugag gcagucgccu acggagcugc cgugcaagca gccauucuca     1200

ugggcgacaa gucagaaaaa guacaggacc uguuacugcu cgauguugcu ccacuuaguc     1260

uggguuugga gacugccggg ggcgugauga cagcacuaau caagcggaau agcaccaucc     1320

cgacgaagca gacccaaauu uuuacaacuu auucugacaa ccagcccgga guccugaucc     1380

agguguacga aggcgagcga gcgaugacca aagauaauaa ccuccugggg cgcuucgacc     1440

uuacagggau uccuccagcu cccagaggug ucccucagau agaggugacu uuugauaucg     1500

acgccaaugg cauucugaac guuaccgcaa cagauaaguc caccgggaaa gugaauaaga     1560

ucacuaucac gaacgacaaa ggaagguugu caaaggaaga gauugaacgg augguacucg     1620

augccgagaa guauaaagcu gaagacgagg uccaacgcga gaagauagcc gcuaaaaaug     1680

cacuggaaag cuacgccuuc aacaugaaga gugugguuuc ugaugagggc uuaaaaggua     1740

agaucuccga aagcgacaag aauaaaauuc uggauaagug uaacgagcua cucucguggc     1800

uggaggugaa ucagcuugcg gaaaaagacg aguuugacca caagagaaaa gaauuggagc     1860

agaugugcaa cccaaucauu acaaagcugu aucagggagg cuguaccgga cccgccugcg     1920

gcacugggua cgucccggga aggccugcua ccggucccac aaucgaagag guggauugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  2924
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt3)

<400>  2924
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

ccagaggccc cgcuaucggg auugaccugg gaaccacaua cuccugcgug ggugucuucc      120

agcacggcaa gguugagaua aucgcaaacg aucaagggaa uaggacuacg ccuucuuaug      180

uggccuuuac cgacacagaa cggcucauug gagaugcggc uaaaaaccag guagccauga      240

auccaacuaa caccaucuuc gacgcaaagc gccuuauugg ccgaaaauuu gaggaugcca      300

cagugcaguc agacaugaag cauuggccgu uccgugucgu gagugaaggu gggaaaccca      360

agguucaggu ggaguacaag ggagaaacca aaacauuuuu cccugaggag aucagcucca      420

ugguccugac uaagaugaaa gaaauagcug aggcauauuu gggcggcaag gugcacucug      480

ccguaaucac cguuccagcu uacuuuaaug auucgcaaag acaggccacg aaagacgcgg      540

ggacuauuac cggauuaaac gugcugagga ucauuaauga acccacagca gccgcuaucg      600

ccuauggucu agauaagaag ggcugugcag ggggagagaa aaacguccuc auauucgacc      660

ugggcggugg gacuuuugau gugucaauuc uuaccaucga ggacggaauu uucgaaguca      720

agagcacagc uggcgauacc caucugggcg gggaggacuu ugacaaucgg auggugaguc      780

acuuggccga agaguucaaa cgcaagcaua aaaaggauau cggaccuaac aaaagagcgg      840

uuaggcggcu ccgcacggcc ugcgaacgag caaagagaac ucuguccucu agcacacagg      900

cuuccaucga gauugacuca cuguacgagg guguggauuu uuauaccagu auaacuaggg      960

cccgguucga ggaacucaau gcugacuuau uccguggcac acuggaacca guagagaagg     1020

cccuucgcga ugcaaaauug gacaaggggc agauccaaga aauugugcug gucggaggca     1080

gcaccagaau ccccaaaaua cagaagcuac uccaggacuu uuucaacggu aaagagcuga     1140

auaagucuau uaacccugau gaggccgugg cuuacggggc ggcaguucag gccgcuaucc     1200

uuaucggcga uaaguccgaa aaugugcaag accuguugcu ccuggauguc acgccauuau     1260

cacugggaau ugagaccgcc ggcgggguga ugacaccgcu caucaaaagg aacacuacca     1320

uucccacaaa gcagacucag accuuuacaa ccuacagcga caaccaaagu ucuguacuug     1380

uucaggugua ugaaggagag cgggcaauga cuaaagacaa uaaccuguug gguaaguucg     1440

aucuaacggg cauaccucca gcuccccgag gggucccuca gaucgaagug acauuugaca     1500

uugaugccaa uggaauccug aacgucaccg ccgcagacaa auccacuggc aaggagaaua     1560

agaucaccau uacaaacgau aaaggucgcc ucagcaagga cgauauagac agaauggugc     1620

aggaggcgga aagguacaaa ucggaggaug aagcuaaucg ggaccgcguu gccgcaaaga     1680

acgcccugga gucuuauacc uacaauauca aacaaacugu ggaggaugaa aaacuuagag     1740

ggaagauuuc cgagcaggac aagaacaaga uccuggauaa augucaggaa guaauuaauu     1800

gguuggacag gaaccagaug gcugagaagg acgaauauga gcacaaacaa aaggagcucg     1860

aacgugucug caauccaauc auaucaaaac uguaccaggg cggacccggc gggggaagug     1920

guggcggggg aagcggcgcc uccggugggc cgacaaucga ggaaguggau ugaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  2925
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt3)

<400>  2925
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggucggcau cgaccugggg uuccaguccu gcuacguugc cguggcuaga gcaggaggua      120

uugagaccau agccaacgaa uauucugaua gguguacacc cgcgugcauc ucauuuggcc      180

cuaagaaucg gaguauuggg gcugccgcaa aaagccaagu aaucuccaac gccaagaaua      240

cugugcaggg auucaaacgc uuucacggcc gagcuuucuc ugacccauuu gucgaggcag      300

aaaagucgaa ccucgccuac gauauugugc agcuuccgac gggucugacc gggaucaaag      360

uuacauauau ggaggaagaa cguaauuuca cuaccgaaca ggugacagcu auguuguuau      420

caaagcugaa ggaaaccgcc gagagcgucc ucaaaaagcc cgugguagac uguguuguga      480

gugucccuug cuuuuacacu gaugcggaaa gaagguccgu gauggacgca acacaaauag      540

ccggacuaaa cugucugcgg cuuaugaaug agaccacggc uguggcccug gcauauggca      600

ucuacaaaca ggauuugcca gcucucgagg aaaagccccg caacgucguu uucguggaca      660

ugggccauuc ugccuaucag guaagcgugu gcgcguuuaa uagagggaaa cugaaggucc      720

uggccacugc auucgauacc acacucggag guaggaaguu ugacgaggug uuaguuaacc      780

acuucuguga agaguuuggc aaaaaguaca aacuggauau uaaguccaaa auccgggcuc      840

uuuugcgccu gucacaggaa ugcgagaagc ucaaaaagcu aaugagugcc aaugcuagcg      900

accugccucu uucuauugag uguuucauga acgaugugga cgucuccggg acuaugaauc      960

gaggaaaguu ccuggaaaug ugcaacgacu ugcucgccag aguggagcca ccccugaggu     1020

caguauuaga acaaaccaaa cugaagaaag aggauaucua cgcaguugaa auagugggcg     1080

gugccacacg gauuccugcu gucaaggaga aaaucagcaa guuuuucggg aaggagcuca     1140

guaccacgcu uaaugcggac gaagcaguga cucguggaug ugcccugcag ugcgcuauuu     1200

ugucuccagc cuuuaaaguc cgcgaguucu ccaucacaga ugugguuccg uaucccauca     1260

gccuaagaug gaacucgccu gcagaagagg ggucuuccga cugcgaagug uuuucaaaga     1320

accaugccgc uccauucagu aaaguacuga ccuuuuacag gaaggagccc uucacucucg     1380

aggccuauua cagcuccccu caggaucugc cauaucccga cccggcaauu gcgcaguuuu     1440

cuguccaaaa agugacaccu cagagcgaug gcucaaguuc caagguuaag gugaaagucc     1500

gggugaaugu acacggcaua uucagcgugu cuucagcuag ucuuguugaa guccauaaga     1560

gcgaggaaaa cgaggagccc auggaaaccg accagaaugc caaagaggaa gagaagaugc     1620

aaguggauca ggaggagcca cacguggagg aacagcagca acagacgccu gcagagaaca     1680

aagccgaauc cgaggaaaug gagaccucuc aggcuggauc gaaggacaag aaaauggauc     1740

agcccccaca agccaagaaa gcaaagguca aaacaagcac uguugaccug cccaucgaga     1800

aucaguugcu cuggcagauu gaccgagaaa ugcugaacuu auacaucgag aaugaaggua     1860

agaugauaau gcaggauaaa cuggagaagg aacgcaacga cgcuaagaau gccguggagg     1920

aguaugugua cgaaaugaga gauaaacuau ccggcgagua cgaaaaguuu guaucagagg     1980

acgauaggaa caguuucacc cucaaacugg aggacacaga aaauuggcuu uaugaggaug     2040

gggaagacca accuaagcag gucuacgugg auaaauuggc ggagcugaag aaccucggac     2100

agccaauuaa gauccgguuu caggaaucug aggagcgccc gaaacuguuc gaggagcuug     2160

gcaagcaaau ccagcaguau augaaaauua ucagcuccuu caagaauaaa gaagaccaau     2220

acgaucaccu ggacgccgcu gauaugacua agguugagaa gucaaccaac gaagcaaugg     2280

aguggaugaa uaacaaauug aaccuccaga auaagcagag ccugacaaug gaccccgugg     2340

ucaaaucuaa ggagauugaa gccaaaauaa aggaguuaac cuccacuugu aguccuauca     2400

uuagcaagcc aaaacccaag guggaaccuc caaaagagga acagaagaac gcugagcaaa     2460

auggucccgu ugacgggcag ggcgauaacc cgggaccuca ggccgcagag cagggcacgg     2520

acacagcggu gccaucugau uccgacaaaa agcugcccga aauggauauc gacugaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  2926
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt3)

<400>  2926
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggucggcau cgaccugggg uuccucaacu gcuacauugc cguugcuaga uccggaggua      120

uagagaccau cgcaaaugaa uauucugaua gguguacacc cgccugcauu ucacuuggca      180

gucggacucg cgcgaucggg aacgcugcca agagccagau ugugacgaau guacgaaaca      240

ccauccacgg auuuaaaaag cugcauggcc guuccuucga cgauccuaua gugcaaacag      300

agagaaucag guugccauac gaauuacaga aaaugccgaa ugguucugca ggggucaagg      360

ugcgguaucu ggaggaagag agacccuuug ccauugagca gguuacugga augcuacucg      420

cuaaacugaa ggaaaccucg gagaacgcac uuaagaaacc uguggccgac ugugucaucu      480

caauucccag cuucuuuaca gaugcugaaa gaaggagugu gauggccgcg gcacagguag      540

ccggccugaa uugcuugcgg cucaugaacg agaccacugc uguugcccug gcauacggca      600

ucuauaagca agaccugcca ccucucgaug agaaaccacg caaugugguc uucauagaca      660

uggggcacuc cgcuuaccag guguuagugu gugccuuuaa caagggaaaa cugaaggucc      720

uugcgacaac cuucgauccc uauuugggug gccgaaauuu ugacgaagcc cugguugauu      780

acuucugcga cgaguuuaag acgaaauaca agauuaacgu gaaagaaaau ucuagagcac      840

uacucaggcu guaucaggag ugugaaaaac uuaagaagcu gaugagcgcu aacgccuccg      900

auuugccucu caauaucgag ugcuucauga acgaccugga cguaucaagu aaaaugaacc      960

gggcucaguu ugagcaauua ugugccagcc ugcucgcacg uguggaacca ccgcuuaagg     1020

ccgucaugga gcaggcuaau cugcagcgcg aagauauuuc uuccaucgag aucguugggg     1080

gagcgacucg cauucccgca gugaaggaac agauaaccaa auucuucuug aaggacaucu     1140

caacaacucu aaacgccgau gaggcugugg ccaggggcug cgcacugcaa ugugccauuc     1200

ucagcccugc uuuuaaaguc cgggaguuca guaucaccga ccuggugcca uacucuauaa     1260

cacuucgaug gaagaccucc uuugaagaug guagcgggga gugcgaagua uucugcaaaa     1320

aucaucccgc cccuuuuucg aagguuauua cguuccacaa gaaagagcca uuugaacugg     1380

aggcauucua uacuaacuug caugaggugc ccuacccgga cgcgcgcauc ggaucuuuua     1440

caauccagaa ugucuucccu caguccgaug gcgacucaag uaaggugaaa gucaagguga     1500

gaguuaacau ucacggcauc uuuagcgugg cuuccgccuc uguaauugaa aaacaaaauc     1560

ucgaggggga ucacagcgac gcacccaugg aaaccgagac uucauucaag aacgagaaua     1620

aggauaacau ggacaaaaug caggucgacc aggaagaggg acaucagaag ugucacgccg     1680

aacauacacc agaggaagag auagaucaca ccggugcuaa aacgaagagu gccguguccg     1740

acaaacaaga uaggcugaau cagaccuuaa agaagggcaa aguuaagagc aucgaccugc     1800

cuauucaguc uucacuaugc cggcagcucg ggcaagaucu gcuuaacagu uauaucgaga     1860

augaaggaaa aaugaucaug caggacaagu uggagaaaga acgcaacgau gcaaagaaug     1920

cuguggagga auacgucuau gacuuuagag auaggcuggg cacaguguac gagaaauuca     1980

uuacucccga ggaccucagc aagcuguccg ccguacuuga agauaccgag aacuggcugu     2040

acgaagacgg ugaggaucag ccaaaacagg uguauguuga caaguugcaa gaacucaaga     2100

aauacgggca gcccauacag augaaguaua uggagcacga ggaacguccu aaagcgcuga     2160

acgacuuagg caagaagauc cagcugguca ugaaagugau ugaggccuac cggaauaagg     2220

augaacgaua ugaccaucua gauccaacag agauggagaa aguggaaaag uguaucucug     2280

acgcuauguc guggcucaac agcaaaauga augcacaaaa caagcugucc cuuacucagg     2340

auccggucgu uaagguguca gagauugugg ccaaaaguaa ggaauuggac aauuucugca     2400

accccaucau auacaaaccu aagccaaaag cugagguacc cgaagauaag ccuaaggcca     2460

auucugagca caacggacca auggacggcc agagcgggac cgagacaaaa uccgauucaa     2520

ccaaggacag cucucaacau acuaaaucca guggagaaau ggaggucgau ugaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  2927
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt3)

<400>  2927
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ugagccucgu ggccgcuaug cuucuguugu uauccgcagc cagagcggag gaagaggaca      120

aaaaggaaga ugucggcacc guugugggga ucgaccuggg aacaacuuac ucuugcguag      180

guguguucaa aaacggcagg gucgagauua uagcuaauga ucaggggaac cggaucacgc      240

ccucauaugu ggccuuuacc ccugaaggag agcgccuaau uggcgacgca gccaagaauc      300

aacucacaag uaacccagag aauacuguuu ucgaugcuaa acgacugauc ggucguaccu      360

ggaacgaccc gagcgugcag caggauauua aguuucuucc cuucaagguc guggaaaaga      420

agacaaaacc uuacauccag guagacauag ggggaggcca aaccaagacu uuugcaccag      480

aggaaaucuc cgccaugguu cugacaaaaa ugaaggagac cgcugaggcc uauuugggca      540

agaaagugac gcacgcgguc gugacugugc ccgcauacuu caaugaugcc cagagacagg      600

cuaccaagga cgccgggaca auugcaggac ucaacgucau gaggaucauu aaugaaccua      660

cugcugccgc gaucgccuau ggucuggaua aacgggaggg cgaaaagaac auacugguuu      720

uugaccucgg gggaggcacc uucgaugugu cuuuacugac aauugacaau gguguauuug      780

agguggucgc aaccaacggg gacacgcauc uuggaggcga agauuucgac cagcgcguga      840

uggagcacuu uaucaaauug uacaagaaaa agacuggcaa ggauguuaga aaagacaaua      900

gggcugugca aaagcugcgg cgcgaggucg aaaaagccaa gcgagcucua ucgucacagc      960

aucaggccag aauugagauc gaaucuuucu augaggggga agauuuuagu gagacacuca     1020

ccagggcaaa auucgaggaa cugaacaugg accuuuuccg guccacuaug aagccagugc     1080

agaagguacu ggaggauucu gacuugaaaa agagcgauau cgacgaaauu guucucgugg     1140

gagguuccac acguauaccc aaaauccaac agcuggucaa ggaguuuuuc aauggcaaag     1200

aaccuucacg cgggauuaac ccagaugagg ccguggcuua cggagcggca guccaggccg     1260

gcguguuaag uggugaccaa gacaccgggg aucugguucu ccuugacgug uguccgcuga     1320

cguugggcau cgagaccgua ggaggcguca ugacaaagcu aauacccaga aacacugugg     1380

uuccuaccaa gaaaagccag auuuuuagca cagcuuccga uaaucagcca acugugacca     1440

ucaaggucua cgaaggggag aggccccuga caaaagacaa ccaccuccug ggaaccuucg     1500

aucuuacugg uaucccucca gcaccccggg gcgugccgca gauugaagua acguuugaga     1560

ucgacgugaa ugggauucug cgaguuacag ccgaggauaa gggaaccggc aacaaaaaua     1620

agauaacuau caccaacgac caaaaucgcu ugacaccuga agagauugaa agaaugguca     1680

acgaugccga gaaguucgcu gaagaggaca aaaagcucaa agagaggauc gauacccgga     1740

augaacugga gucauaugcc uacagcuuaa agaaccagau cggugacaaa gaaaagcuag     1800

ggggcaaacu gaguucugag gauaaggaaa cuauggagaa ggcaguggag gagaaaauug     1860

aauggcucga aucccaucag gacgcggaca uagaggauuu uaaggcuaaa aagaaagaac     1920

uggaggagau cgugcagccc auuaucagca aacuuuaugg aucggccggc ccaccuccca     1980

caggggaaga ggacacggca gaaaaggaug aguugugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  2928
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt3)

<400>  2928
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

cccccagaga gcuggcugug ggcaucgacc ucgggaccac auacagcugc gucggaguuu      120

uccaacaggg uaggguggaa auucuugcaa acgaucaggg caaucggacu acgccuuccu      180

auguagccuu uaccgacaca gagcgccugg ugggggaugc ggcuaagucu caggccgcau      240

ugaacccaca caauacuguc uucgacgcca aacgauuaau aggacguaag uuugcugaua      300

ccacagugca aucagacaug aaacauuggc cguucagagu ugugagugaa ggcgguaagc      360

ccaaagucag gguguguuac cgcggggagg auaagaccuu uuauccugaa gagaucagcu      420

ccaugguacu gucuaagaug aaagagacug cagaagccua ccuaggacag ccaguuaagc      480

acgcugugau uacagucccc gccuauuuca acgacucgca gcggcaggcg accaaagaug      540

caggcgccau cgcuggccuc aaugugcuga gaauuaucaa cgagccuacg gccgcagcua      600

uagccuacgg gcuugacagg cggggagcgg gugaacgcaa ugugcugauc uuugauuugg      660

gcgggggaac uuucgacguc ucaguucuca gcauugaugc cggcguguuu gagguaaagg      720

caaccgcugg ugacacacau cucgggggag aggacuucga uaaccgacug gugaaucacu      780

uuauggaaga guucagaagg aaacauggca aggaccugag uggcaacaag cgggccuuac      840

gucgccugag aacugcuugc gaaagggcca aacggacccu uuccucuagc acacaagcaa      900

ccuuggagau cgauucccug uuugaagggg ucgacuucua uacgucaauu acucgagccc      960

gcuucgagga gcuauguagu gaucucuuua gaagcacacu ggaaccagug gagaaggcuc     1020

uuagggacgc gaaacuggau aaggcacaga uccacgacgu uguguugguc ggagguucua     1080

cccggauacc caaagugcag aagcuccugc aggauuucuu uaauggcaaa gaauuaaaca     1140

aguccauuaa uccugacgag gccguagcuu acggggccgc aguucaagcc gcugugcuga     1200

ugggagauaa gugcgaaaaa guccaggacc uccuucuguu ggacguggcc ccacuaucac     1260

ugggccucga gacugccggu ggggucauga caacccugau ccagcgcaac gcgacgauuc     1320

cgaccaagca aacacagacu uucaccacau acagcgauaa ucagcccggc guguuuaucc     1380

agguuuauga gggagaaaga gcuaugacua aagacaacaa ccuucugggc agguucgagu     1440

ugagugggau cccuccagca ccccguggag ugccucaaau ugaaguaacc uuugauauag     1500

acgcaaaugg uauccucucu gucacagcca ccgaucgguc cacuggcaag gcuaacaaaa     1560

uuacgaucac aaaugacaag gggcgacuga gcaaggagga aguggagaga augguucacg     1620

aggccgaaca guacaaagca gaggaugaag cucagaggga ccgcguggcc gcgaagaacu     1680

cguuagaggc ccaugucuuc cacgugaaag gaucucugca ggaggaaucc cuacgggaua     1740

agauaccaga ggaagacaga aggaaaaugc aagauaagug ucgcgaggua cucgcuuggc     1800

uggaacauaa ucagcuugca gagaaggagg aauaugagca ccagaaacga gaauuggagc     1860

agauuugccg gcccaucuuu ucacgucugu acggcggucc gggggugccu ggcggaagua     1920

gcuguggcac ccaagccaga cagggggacc ccuccacugg accaaucauu gaagagguug     1980

auugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  2929
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt3)

<400>  2929
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

cccccagaga gcuggcugug ggcaucgacc ucgggaccac auacagcugc gucggaguuu      120

uccaacaggg uaggguggaa auucuugcaa acgaucaggg caaucggacu acgccuuccu      180

auguagccuu uaccgacaca gagcgccugg ugggggaugc ggcuaagucu caggccgcau      240

ugaacccaca caauacuguc uucgacgcca aacgauuaau aggacguaag uuugcugaua      300

ccacagugca aucagacaug aaacauuggc cguuccaggu ugugagugaa ggcgguaagc      360

ccaaagucag aguguguuac aggggagagg auaagaccuu uuauccugaa gagaucagcu      420

ccaugguacu gucuaagaug aaagagacug cagaagccua ccuagggcag ccaguuaagc      480

acgcugugau uacagucccc accuauuucu cgaacucaca gcggcaagcc acgaaagacg      540

cgggcgcaau cgccggccuc aaggugcugc cuauuaucaa ugaggcuacu gccgcagcua      600

uagccuacgg gcuugaucgc agaggagcgg guaaaaggaa cgugcugauc uuugacuugg      660

gcgggggaac cuucgauguc agcguucuca guauugacgc cggcguguuu gaaguaaagg      720

caacagcugg ugauacucau cuugggggag aggacuucga caaucggcug gugaaccacu      780

uuauggagga guuccgccga aagcauggca aagaucucuc cggcaauaag agagccuuaa      840

ggcggcugcg uaccgcuugc gagcgcgcca aaagaacacc aucuagcucc acccaggcaa      900

cgcuugaaau cgacucauug uuugaggggg ucgauuucua uaagaguauu acuagggccc      960

gguucgaaga acuguguagc gaccuauuuc gaucuacacu cgagcccgug gaaaaagcuc     1020

ugcgcgaugc gaagcuggac aaagcacaga uccacgauuu cguucuggga gguggcuugc     1080

acucccaucc ucagggggcc gagguggcug ccggacuccu gcaaagacag ggcgcagaac     1140

aggagcacca accaugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  2930
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt3)

<400>  2930
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagca       60

agggccccgc cguggggauc gaccugggaa ccacauacuc cugcgucggu guuuuccagc      120

acggcaaagu ggagauuaua gcuaacgauc aagggaauag aacuacgccu ucuuauguag      180

cauuuaccga cacagaaagg cucaucggag augccgcgaa gaaccaggug gcuaugaauc      240

caacuaacac cgucuucgac gccaaacggc uuauuggccg ccgauuugau gacgcagugg      300

uucagucaga uaugaagcau uggccguuca ugguggucaa ugacgccggu cgucccaaag      360

ugcagguaga guacaagggg gaaacaaaga guuuuuaucc ugaggaaguu agcuccaugg      420

ugcugaccaa aaugaaggag aucgcugagg cauacuuggg aaaaacuguc acaaacgccg      480

uggugaccgu cccagcuuau uucaaugauu cucaaagaca ggccacgaag gacgcgggca      540

cuauugcagg cuuaaacguu cugaggauca uaaaugaacc caccgccgcu gccaucgcau      600

acgggcuaga uaaaaaggug ggagcugagc ggaacguacu cauuuuugac cuggguggcg      660

ggacauucga ugugucgauc cuuacuauug aagacggaau cuuugagguc aagucaaccg      720

ccggcgacac acaccugggu ggggaggauu ucgacaaucg cauggugaac cauuuuauag      780

cggaauuuaa aagaaagcac aaaaaggaua uuagcgagaa uaaaagggcc guucggcgcu      840

ugcgaaccgc augugaaaga gcuaagagga cgcucaguuc cucuacucag gccagcaucg      900

agauugacuc ccuguaugaa ggaaucgauu uuuacacauc aaucacccgg gcucguuucg      960

aggagcugaa cgccgaccuc uuccgcggca cuuuagaucc uguggaaaaa gcacugagag     1020

acgccaaacu ugauaagagu cagauucaug acauagucuu ggugggcggg agcacaagga     1080

ucccaaagau ucaaaagcug cuacaggauu ucuucaaugg aaaagagcuc aacaagucua     1140

ucaaccccga cgaagcugua gcguacggug cagccguuca ggcugccaua cuguccggcg     1200

acaaaucaga gaaugugcag gaucuucugu ugcucgacgu caccccucug agcuuaggga     1260

uugaaacggc aggaggcgug augaccgucc ugaucaagcg gaacacaacu aucccaacca     1320

agcaaacaca gacuuuuacc acauauagug auaaucagcc gggugugcuc auucaaguuu     1380

acgaggggga gcgagccaug accaaagaca acaaucuucu gggcaaguuc gaauugacug     1440

gaaucccucc cgcuccacgc ggcgugcccc agauugaggu aacguuugau auagacgcca     1500

acgggauccu aaaugucucu gcaguggaua aauccacagg aaaggaaaac aaaauuacca     1560

ucacuaauga caaggguaga cugagcaagg aggauaucga aaggaugguu caggaggcgg     1620

agaaauauaa ggcugaagac gagaaacagc gggauaaggu gucgucuaaa aacucccucg     1680

aaucauacgc cuucaauaug aaggcaaccg ucgaggacga gaagcugcaa ggcaaaauua     1740

acgaugaaga caagcagaaa auacuugaca agugcaauga gaucauuaac uggcuggaua     1800

aaaaucagac agccgaaaag gaggaauuug agcaccagca aaaagaguug gaaaaggugu     1860

guaacccuau cauuaccaag cucuaucaga gugcuggggg aaugccaggc gguaugcccg     1920

ggggcuuccc gggaggcggg gccccuccca gcggaggugc auccucuggc ccaacuaucg     1980

aggaaguaga cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  2931
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt3)

<400>  2931
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauca       60

gcgccuccag agcugcagcc gcgaggcugg ugggcgcugc cgcaucucgg gggcccaccg      120

ccgcucgcca ccaggacuca uggaacggac ucagucauga ggcauuccga cuugucagcc      180

guagagauua cgccuccgaa gcuauuaagg gugccguugu gggcauagac cuggggacaa      240

cuaauucuug cguagcggug auggagggaa aacaagcaaa ggucuuggaa aacgccgagg      300

gcgcuaggac gaccccuucg gugguugccu uuacagcaga uggugaacgg uuagugggga      360

ugccagcuaa acgccaggcc gucacuaauc cgaacaauac cuucuaugcg acaaagagac      420

ugaucggaag gcgguacgac gaucccgagg ugcagaaaga cauuaagaac guaccuuuua      480

agaucguucg cgccucaaau ggcgaugcau ggguggaggc ucacggcaaa cuauauagcc      540

caagucagau uggggccuuc guccucauga agaugaaaga aaccgcugag aacuaccugg      600

gacauacugc caagaaugca gugaucacag ugcccgccua uuuuaacgac ucccaacgac      660

aggcuaccaa agaugcgggu cagauaucug gccuuaaugu ccugagaguu aucaacgaac      720

cuacggcagc cgcuuuggcc uacgggcucg acaagagcga ggauaaggug auugcaguau      780

augaccuggg aggcgguacu uucgauaucu ccauucugga gauccagaaa gggguguuug      840

aagucaaguc aaccaaugga gacacauucc ucggcggcga ggacuuugau caagccuuac      900

ugaggcacau agugaaagag uucaagcggg aaacuggggu ugaccuuacc aaagauaaca      960

uggcuuugca gcgugugcgc gaagccgcag agaaggcgaa augugagcug aguagcucug     1020

uccagacaga cauuaaucua ccauaccuca ccauggauuc cucaggaccc aagcaucuga     1080

acaugaaguu gacgagagcu caguuugaag guaucgugac ugaccugauu aggcggacaa     1140

ucgccccuug ccaaaaagca augcaggaug ccgagguaag caagagugac aucggcgaag     1200

uuauuuuggu cgggggaaug acccgaaugc caaaagugca gcaaacugug caggaucucu     1260

ucggccgcgc uccgucuaag gccgucaacc ccgacgaggc aguggcuaua ggugccgcga     1320

uccaaggggg cguucuggcc ggagauguga cagacguauu acugcucgac gucaccccuc     1380

uuucccuggg cauugaaacg cuugggggag uguuuaccaa acuaaucaau agaaacacaa     1440

cuauaccaac caaaaagagc cagguuuucu cgacagcugc agauggucag acucaggugg     1500

agauuaaggu cugucagggc gagagggaaa uggccgggga caauaagcug cucggacagu     1560

ucacccugau cggcauuccc ccugcuccac ggggugugcc ccaaaucgag guaacauuug     1620

auaucgacgc caacgggauu gugcacguuu cugcaaaaga uaagggcacc ggacgcgaac     1680

agcagauagu cauccagucc ucaggcgggc uuaguaaaga cgauauugag aauaugguga     1740

agaacgcgga aaaguacgcc gaggaggaca gaaggaaaaa ggaacgugug gaggcuguca     1800

auauggccga aggaaucauc cacgauacug agacgaaaau ggaggaguuc aaggaccaac     1860

ugccggcaga ugaaugcaac aaauugaagg aagagauuag caagaugcgg gaacuccugg     1920

cucgaaaaga cuccgagaca ggugagaaua uaagacaggc cgcaucuagc uuacagcagg     1980

ccucacugaa gcuauuugaa auggcuuaua aaaagauggc gagugagagg gaaggcuccg     2040

ggagcucugg aaccggcgag caaaaagaag aucagaagga ggagaaacag ugaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  2932
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt3)

<400>  2932
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaggaggc uggcgggagc gauggaccca gagaaaccgc accuacaucc gccuacucuu      120

caccagcgag gagucugggu gacacuggca ucacgccgcu cagccccucc cacauuguga      180

acgauaccga cucuaauguc ucggagcagc aaucauuccu uguuguggua gcuguggauu      240

uugggacaac uagcagugga uaugccuacu ccuucaccaa agaaccugag ugcauacaug      300

ucaugcggcg cugggaaggc ggugacccag gggugucuaa ccagaagaca cccaccacua      360

uccuguugac accugagcga aaauuucaca gcuucggaua ugcagcccgu gauuuuuacc      420

augacuuaga uccaaaugag gcuaagcagu ggcuguaucu agaaaaauuc aagaugaagc      480

uccacaccac gggcgaccug acuauggaua ccgaccuuac agcagccaac ggcaaaaagg      540

uuaaagcucu ggagauuuuu gccuacgcgu ugcaguauuu caaggaacaa gcacucaaag      600

agcuguccga ucaggccggg ucagaguuug aaaauaguga cgugagaugg gucaucacug      660

ugcccgcuau uuggaagcag ccugccaagc aguucaugag gcaagcagcu uaccaggccg      720

gacuggcgag cccagagaac ucugaacagc ucaucauagc cuuagagccg gaagcagcuu      780

ccaucuacug ucggaaacug cgccuucauc agaugauuga guugucaagc aaggccgcug      840

uaaaugguua uaguggcucu gacaccguug gggccggauu uacacaagca aaagagcaca      900

ucagaaggaa ccggcagucc cgcaccuucc ugguggaaaa ugucauuggc gagaucugga      960

gcgaacuaga ggaaggugau aaguacgugg uggucgacuc cgggggaggc acgguugauc     1020

ucacugugca ccagauacga cugcccgagg gccaucuuaa agagcuguau aaggccacag     1080

ggggaccuua cgguucuuug ggcguagacu augaauuuga gaaacuccug uacaagauuu     1140

ucggggaaga uuucaucgag caauuuaaga uuaaaagacc agcugcgugg guggacuuaa     1200

ugaucgcauu cgaauccagg aagcgggccg cugcccccga ucguaccaac ccucugaaua     1260

ucacucuccc auuuucauuc auugacuauu acaaaaaguu ucgcggacac agugucgagc     1320

augcacuuag aaaaagcaac guggauuucg uuaagugguc cucucagggc augcugagga     1380

ugagccccga cgccaugaau gcuuuguuua agccgacaau agauucaauc auugagcacc     1440

uacgggaccu guuccagaaa ccugaaguga guaccgucaa guuucucuuc cuggugggug     1500

gguuugccga ggcaccccuu cugcagcaag cgguacaggc ugccuucggc gaccagugcc     1560

gaaucauaau uccacaggau guuggauuga cgauccucaa aggcgcagug cuguuugggu     1620

uagacccugc cgucaucaag gugcgcagau cgccccugac cuacggaguc ggugugcuaa     1680

acagguaugu ugaaggcaaa cacccacccg agaagcuccu ggugaaggau gggacacggu     1740

gguguacuga cguauucgau aaauucauua gcgcugacca aucugucgcc cuuggagagu     1800

uggugaagcg cucauacacc ccugcaaaac caagucagcu gguuaucgug auuaauauau     1860

auagcuccga acaugauaac gucucuuuua ucacagaccc gggcgugaag aaaugcggua     1920

cucucagacu ggaucuuacc gggacaucgg gcaccgcugu acccgccagg cgugagauuc     1980

agacucugau gcaguucgga gacacggaaa ucaaggcgac agccaucgau auugcuacca     2040

gcaaguccgu gaaaguuggc auagacuuuu ugaacuacug aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  2933
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt3)

<400>  2933
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugg       60

ccgugcccga gaugggccuc caggggcuuu acaucggaag cuccccugaa agaucuccag      120

ucccgucacc cccugguagu ccaaggaccc aagagagcug cggcauugcu ccccugacac      180

cuucccaguc uccaaagccc gaaguucggg caccucagca ggccucguuc ucagugguag      240

uggcgauaga cuuugggacu acgagcagug gauaugcuuu cuccuuugcc ucugauccag      300

aggcaaucca caugaugcgc aaaugggaag gcggugaccc gggggucgcc caccaaaaga      360

cccccacaug uuuguuacug acuccugagg gagcuuucca cagcuuuggc uacaccgcac      420

gagauuauua ccaugaccua gauccagagg aagcccguga cuggcucuau uucgagaaau      480

uuaagaugaa aauucacucc gcuacagauc ugacccuuaa gacucagcug gaagccguga      540

acggcaagac aaugcccgcg uuggagguuu ucgcacaugc ccucagauuu uucagggagc      600

acgcucugca ggaacugcgg gagcagucac cuagucuccc agaaaaagac accgugcgcu      660

gggucuuaac ggugcccgcc aucuggaagc aaccggcaaa acaguuuaug agagaggcug      720

ccuaccuggc ggggcuugua agcagggaaa augccgagca guugcugauu gcacuagagc      780

cugaagcugc cucuguuuau ugccggaagc uccgccugca ccagcuucug gauuuguccg      840

gacgagcucc cgguggcggg agacucggag agaggcgguc aaucgacagc aguuuccguc      900

aagcccgcga acagcugaga aggucucggc auucccgaac cuuuuuagug gagagcggcg      960

ucggugaacu gugggcagag augcaggccg gggaucgcua cgugguggcu gacuguggag     1020

gcggcacugu cgaucucaca guucaccaac uugagcagcc acaugggacu cugaaagaau     1080

uguacaaggc gucgggaggu ccuuauggcg cagugggggu agaccuagcc uucgagcagc     1140

ugcucugcag aauauucgga gaagacuuua ucgcuaccuu caagaggcag cggcccgccg     1200

caugggugga ucugacaauu gccuuugagg cucgcaaaag aaccgccggc ccacacaggg     1260

cgggugcacu uaacaucucu cugcccuucu ccuuuauuga cuucuaccgu aagcaacggg     1320

ggcacaaugu cgaaacggcu uugcgaagau caagugugaa cuuuguuaaa uggagcuccc     1380

agggcaugcu caggaugucu ugugaggcca ugaaugagcu guuccagccu acugugagcg     1440

gaaucauaca gcauauugaa gcauuacugg cccgcccaga gguccaaggc gugaagcuac     1500

ucuuucuggu agggggauuc gcugaaucag ccguucuuca gcacgcagug caggcugccu     1560

ugggugcgcg gggccugaga gucguggucc cgcaugaugu ggggcucaca auccugaaag     1620

gagccguucu uuuuggccag gcucccggug ugguaagggu ccgccgaagu ccucugaccu     1680

augggguggg cguuuugaac cgguucgugc caggacguca ucccccugag aagcuccugg     1740

ucagagacgg caggcgcugg ugcacugaug uguuugagcg guucguagca gccgaacaau     1800

ccguggcuuu aggggaggaa guuagaagga gcuacugucc agcccgaccc ggacagcgcc     1860

ggguccugau uaaucuauau ugcugugcag cggaggacgc cagauucauc acagauccgg     1920

gugugaggaa augcggcgcu cucucucugg aacuugagcc ugccgacugu gggcaggaua     1980

ccgcaggagc uccacccggc cgucgcgaga uccgggccgc aaugcaguuu ggugacacgg     2040

aaauuaaggu gaccgccguc gauguuucaa caaacagaag ugugagggcu agcauagacu     2100

ucuuguccaa uugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  2934
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt3)

<400>  2934
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

gggagaugac cauccugggc agcgcugugc ucacacuucu guuggcaggg uacuuagccc      120

agcaauaucu gccccuaccu acuccaaagg ucauuggaau agaccucggu acgaccuacu      180

gcuccguugg cguguucuuu ccggggacag gaaaaguaaa ggugaucccc gaugaaaacg      240

gccacauuuc uaucccuuca auggucaguu ucacugacaa ugauguguau guugguuacg      300

agagcgugga acuggcggac uccaacccac agaauaccau uuaugaugcu aaaagguuua      360

ucgggaagau auucacagcc gaggaacuug aggcagagau cggacgguac cccuuuaaag      420

uccugaacaa gaauggcaug guggaguucu cuguaaccuc gaacgaaacu auuacaguuu      480

caccugaaua ugugggcagc cgcuugcucc ugaagcugaa agagauggcc gaggcuuacc      540

ucgggaugcc agucgcaaau gccgugauca gugugcccgc ugaauuugac uuaaagcagc      600

gaaacuccac cauugaggcc gcgaaucugg caggacuuaa aaucuugcgu gucauaaacg      660

aaccuacggc cgcugccaug gcauacgguc ugcauaaggc ugauguuuuc cacgugcuag      720

uaauugaccu cggcggggga acucuggaug ugucucuucu gaauaaacag ggcgguaugu      780

uuuugaccag agccaugagc gggaacaaua agcucggagg ccaagacuuc aaccagaggc      840

uguuacagua ucuguacaag cagaucuauc aaacauacgg cuuuguccca ucccggaaag      900

aggaaauuca ucgccucaga caggcggugg agaugguuaa guugaaucug acuuugcacc      960

agucagccca gcuaagugug cugcucaccg ucgaggaaca agauaggaaa gagccgcaua     1020

gcucugacac agaacugccc aaggauaaac uuuccucagc agacgaccac cgggugaaca     1080

gcggguucgg acgcggucug agugauaaga aaucuggcga gucccaggua uuguuugaaa     1140

ccgagaucag ccgaaaacuc uucgacacgc ugaacgagga uuuauuccag aagauccugg     1200

uuccuauuca acaggugcua aaggaagggc accucgagaa gacugaaaua gacgaggucg     1260

ugcuggucgg aggcucgaca agaaucccaa ggauuagaca ggugauccag gaauuuuucg     1320

guaaagaucc caauaccucu guugacccug aucuugcugu gguaacuggg gucgccauac     1380

aagcuggcau ugacggaggc uccuggccac uucagguguc agcccuggag auccccaaca     1440

agcaucucca gaaaacaaau uuuaacugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  2935
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt3)

<400>  2935
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

cuaucggcgu gcaccugggg ugcaccagcg caugugucgc cguuuacaag gacgguagag      120

cgggaguggu agcuaacgau gccggcgaca gggugacacc cgcagucgug gccuauuccg      180

agaaugaaga gauuguuggg cucgcugcaa aacagucucg gauacgcaac aucucaaaua      240

cugugaugaa ggucaaacaa auucuuggac gaaguagcuc cgauccucag gcccagaagu      300

acaucgcuga aucuaaaugc cuggugauug agaagaacgg caaguugcgu uaugaaaucg      360

acacggguga ggagaccaaa uucguaaauc cagaagaugu ugccagauua auauuuucga      420

agaugaaaga gacagcgcau ucagugcugg ggagcgacgc aaacgauguc gugaucacug      480

ugccguucga cuuuggagaa aagcagaaaa augcccuagg cgaggcugcc agggcagcug      540

gcuucaacgu ccuccggcug auucacgagc ccagugccgc gcuucuggcc uacgggaucg      600

gacaagauuc cccuaccggu aagucuaaua uuuugguuuu uaagcucggc gggacaagcc      660

ugucccuguc agugauggaa guaaacagug gaaucuaucg cgugcucagc accaauacug      720

acgauaacau aggcggugca cauuucacag agaccuuagc ucaguaccug gccucugaau      780

uucagagauc cuucaaacac gacgucaggg ggaaugcucg ggccaugaug aagcugacga      840

acucagcaga gguggccaaa cauagcuuga guacucuggg aucugcuaau uguuuucuag      900

auucccucua ugaaggccag gacuucgacu gcaacguuag ccgcgcgcga uuugagcugc      960

uuuguucgcc acuguucaac aagugcauug aggcaaucag aggcuugcuc gaucaaaaug     1020

gguuuaccgc cgacgauauu aacaaagugg uccugugugg agguucuucc aggaucccca     1080

aguuacagca gcugaucaaa gaccucuucc cugcugugga acuucuuaau ucaauuccac     1140

ccgaugaggu aauaccuauc ggcgccgcaa uugaagccgg gaucuugaua ggaaaggaga     1200

accuacuggu ugaagacagu cucaugauug agugcagcgc ucgggauauc cuggugaagg     1260

gcgucgacga guccggugcc ucucguuuca cagugcuuuu uccaagcggg acuccgcugc     1320

ccgcacgcag acagcacacc uugcaagcgc cuggcucaau caguuccguc ugucucgaac     1380

uguacgagag cgauggcaaa aauucugcua aggaagagac aaaauucgcc caggugguuu     1440

uacaggaccu ggauaagaaa gaaaacggac uaagggacau ucucgcagug cugaccauga     1500

agcgggacgg gucacuucac guaacgugca cugaucaaga gacaggaaag ugugaggcca     1560

ucaguauuga aauagcuagc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  2936
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt3)

<400>  2936
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggucggccu ggacguuggg ucccagucuu gcuacaucgc cguggcuaga gcaggaggua      120

uugagaccau agccaacgag uucucagaua gguguacacc caguguaauc agcuuuggcu      180

ccaagaaucg gacuauuggg guggcggcua aaaaccaaca gaucacgcac gccaauaaca      240

ccgucucuaa uuucaagcgc uuucauggac gagcauucaa cgacccuuuu auucagaaag      300

agaaggaaaa ucucucguau gaucuugugc cacugaaaaa cggcgguguu gggaucaagg      360

ugauguacau gggagaggaa cacuuguucu cagucgagca gauaacagcc auguuacuga      420

cuaagcuaaa agagaccgcu gaaaauagcc ucaagaaacc ggugacagac ugcguaauca      480

guguucccuc cuuuuucacc gaugcagagc guagaucugu gcuggacgcc gcucaaauug      540

ucggccuuaa cugucugagg uugaugaaug auaugacugc cguggcgcuc aacuauggca      600

ucuacaagca ggaccugccu agccuggaug aaaaaccacg gauugugguc uuuguugaca      660

uggggcauuc cgcauuccag gugucagccu gcgcuuuuaa uaagggaaag cucaaaguau      720

uagguacagc cuucgauccc uuucugggcg ggaagaacuu cgacgagaaa cuuguggagc      780

acuucugugc agaauuuaag accaaauaua aguuggaugc uaaaaguaag auccgcgccc      840

ugcuaagacu cuaccaggag ugcgaaaagc ugaaaaagcu gaugagcucu aauuccacgg      900

accuuccuuu gaacauagag uguuucauga acgacaaaga ugucucagga aagaugaaua      960

ggagccaauu ugaagaacuc ugcgcggagc uguuacagaa aauugaagug ccacuguaua     1020

gucuccuuga gcagacucau cugaagguug aagacguguc ugccgucgag aucgugggcg     1080

gugcaacccg gauucccgcu guaaaggaac gcaucgccaa auucuuuggg aaggauaucu     1140

ccacaacuuu gaacgcugac gaggccguug cacgaggaug ugcccuacag ugcgcuauuc     1200

ugagcccugc guucaaagug agagaguuuu cggucaccga ugcagugcca uucccgauau     1260

cucucaucug gaaucacgac uccgaagaua cagagggcgu ccacgaagug uuuucaagga     1320

accaugccgc ucccuucagu aagguucuga ccuuucuucg gcguggcccu uucgagcugg     1380

aagccuuuua cagcgaccca caaggggugc ccuacccuga ggcaaaaauu ggacgcuucg     1440

uaguccagaa uguguccgcc cagaaggaug gugagaaguc uagaguuaaa gugaagguca     1500

gggugaacac gcacggcauc uucacuauaa gcacagcuuc aaugguagaa aaagugccaa     1560

ccgaggaaaa ugagaugagu uccgaggccg acauggaaug uuugaaccaa cggcccccgg     1620

agaauccuga uacugacaag aacguucagc aggacaauag cgaagcaggg acacagcccc     1680

aaguccagac cgaugcgcag cagacgucuc aaucaccacc uagucccgag cucaccagcg     1740

aagagaacaa aauuccagac gcugauaagg ccaaugagaa gaaaguggac cagcccccug     1800

aagcaaagaa accaaagauc aaagugguca acguugagcu gccgaucgaa gccaauuuag     1860

uguggcagcu gggaaaggau cuacucaaca uguauauuga gacagaaggc aaaaugauca     1920

ugcaggacaa gcuggagaag gagcgaaacg augcuaaaaa ugccguggaa gaguacguau     1980

augaauuucg cgacaaacuu ugcggucccu acgagaaauu cauuugcgaa caagaucauc     2040

agaacuuuuu gagacugcuc acugagaccg aggacuggcu guaugaagag ggggaagauc     2100

aggcaaagca ggcuuacguc gacaaacuug aggagcugau gaagauaggc acaccuguga     2160

agguuagguu ccaagaagcc gaggaacggc caaaaauguu ugaggaauug ggacagcgcc     2220

uccagcacua ugcgaagauc gccgcugauu ucagaaauaa agacgagaag uacaaccaca     2280

uugacgaguc cgaaaugaaa aagguggaga agucugucaa ugaagugaug gaguggauga     2340

acaauguuau gaacgcacaa gccaaaaagu cgcuggauca ggaccccgug guaagggcuc     2400

aggaaaucaa aacuaagauc aaagaguuaa auaacaccug ugagccuguc gugacacagc     2460

caaagcccaa gauugaaagc ccgaaacugg agcguacccc uaauggccca aacauagaua     2520

agaaagaaga ggaccuagaa gauaagaaua acuuuggggc cgagcccccu caucaaaaug     2580

gagagugcua ccccaacgaa aagaacuccg ugaauaugga ccucgauuga ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  2937
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt3)

<400>  2937
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaggugag aaggcagcgg ccccgccgac gugucugcug ggcucugguu gcagugcucc      120

uugccgaucu guuggcguua agcgacaccc uggcuguaau guccguggau cuaggcucug      180

agucaaugaa agucgccauc gugaagccug ggguuccaau ggaaauugug cucaacaaag      240

agaguagaag gaagacaccg gucauaguga cucugaaaga aaaugagcgg uucuuuggag      300

acagcgcagc cuccauggcu aucaagaacc ccaaggcaac gcuucgcuac uuccaacacc      360

uguuggguaa acaggccgau aauccucaug uagcucucua ucaggccaga uuuccagaac      420

acgagcugac cuucgacccc cagaggcaaa caguucauuu ucagauuucu ucgcagcugc      480

aguucucacc ugaggaagug cucggcaugg ucuuaaacua cagccggagu cuggcggagg      540

auuuugcaga acaaccaauc aaggacgccg ugauuacugu gcccgucuuc uuuaaucagg      600

cugagcgccg agccguucuu caggcagcua gaauggccgg guugaaagug cugcagcuaa      660

ucaacgauaa uaccgcgaca gcccucuccu auggaguauu caggcggaag gacauaaaca      720

ccacugcaca aaauaucaug uuuuacgaua ugggcucugg uagcacagug uguaccauug      780

ucacguauca gauggugaaa acuaaggagg cugggaugca gccucaacug cagauccgug      840

gaguuggcuu cgaccgcacc cuuggcgggc uggaaaugga guugagacuc agggaacggc      900

uggccggauu auuuaacgag cagcgaaagg gucagcgcgc uaaagaugug agagaaaauc      960

caagggccau ggcaaagcug cuccgggagg ccaaccgccu uaaaacaguc cuguccgcua     1020

augcggacca cauggcacaa auugagggcu ugauggacga uguggacuuc aaggccaaag     1080

uaacuagagu ugaguucgag gaacuaugcg cugaucuguu ugagagggug ccggggcccg     1140

uccagcaggc ccuccaguca gcagaaauga gucuggacga gaucgagcaa gugauacuug     1200

ucggaggcgc cacccgugug ccucggguuc aggaagugcu guugaaggcu guagguaaag     1260

aggaacucgg gaagaacauu aaugccgaug aggcagcggc uaugggagcc gucuaccagg     1320

cagccgcucu gagcaaggcc uucaaaguga agccauuugu ugugcgagac gcagucgugu     1380

aucccaucuu aguagaguuc acaagagagg uggaggaaga accuggcauu cauucucuga     1440

aacacaacaa gaggguucua uuuucccgca ugggcccaua cccccagcgg aaagucauca     1500

ccuucaacag auacucacac gauuuuaauu uccauaucaa cuauggggac cucggauuuc     1560

uggguccgga agaucuuagg guguucggca gccaaaauuu gacgacugug aagcugaagg     1620

gggucggaga caguuuuaaa aaguacccug auuaugaguc uaaaggcauu aaggcucacu     1680

ucaaccucga cgaguccggu guucugagcc uugaccgcgu ggaaucggug uuugagacac     1740

ugguagaaga uucugccgag gaagagucca ccuugacuaa acucgggaau acaauaucaa     1800

gucuguucgg cggaggcacc acgcccgacg cgaaggagaa cgggaccgau acaguccagg     1860

aagaggaaga gagcccagcc gaaggaucca aggacgagcc uggugaacag guggaauuaa     1920

aagaggaagc ugaggcaccc guugaagaug gcucucagcc acccccucca gagccgaagg     1980

gggacgccac ucccgaggga gaaaaagcua ccgagaagga aaauggcgau aaaagcgagg     2040

cccaaaagcc uucagagaag gcagaagcgg guccagaggg gguggccccc gcuccugaag     2100

gcgagaaaaa gcagaaacca gcccgaaagc ggcguauggu cgaagagauc ggaguggagc     2160

ugguugugcu agaccucccc gaucugccgg aagacaaacu ugcacagagu guacaaaagu     2220

ugcaggaucu gacacucaga gaccuggaga aacaggaaag ggagaaggcu gccaacuccu     2280

uagaagcauu cauuuuugag acucaggaua agcuguacca accugaguau caggaaguca     2340

gcaccgagga acagcgcgag gaaaucucug gcaaacuuuc agccgcuagu acaugguugg     2400

aggacgaggg ggugggagcg accacuguga ugcucaagga aaaacuggcc gagcuacgga     2460

agcuguguca gggucucuuc uuuagagucg aagagaggaa aaaguggcca gagcgacuga     2520

gcgcacuuga caauuugcug aaccauuccu cuauguucuu aaagggcgcu cgccucauac     2580

ccgaaaugga ucaaauuuuu acggagguug aaaugacaac ccuggagaaa gugaucaaug     2640

aaacuugggc cuggaagaac gccacccuug cugagcaggc aaaacugccu gccacagaga     2700

agcccguauu gcucucgaaa gacaucgaag cgaagaugau ggcucuggau cgggaggugc     2760

aguaccuacu gaauaaggcc aaauucacca agccaagacc uaggcccaaa gacaagaacg     2820

ggacucgugc agaaccaccg cucaaugcca gcgcuuccga ucagggagag aaagucauuc     2880

cucccgcagg ccaaacagaa gacgccgagc caaucucaga gcccgaaaag guggagacgg     2940

guagugaacc uggggauacc gagccacugg aacuuggcgg acccggcgcg gagccugagc     3000

agaaggaaca gucuacuggg caaaaacgcc cguugaagaa cgacgagcug ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  2938
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt3)

<400>  2938
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggaaaccca gacacaagac cagccuaugg aggaagagga aguggagacu uucgccuuuc      120

aggcugagau cgcacagcug augagccuca uuauaaacac guucuacucc aauaaggaaa      180

ucuuucuuag agagcugauu ucuaacucaa gugaugccuu ggacaaaauc agguaugaga      240

gcuuaaccga uccauccaag cuggacucug gcaaagagcu acacauuaau cucaucccga      300

acaagcaaga ucggacacug acuauagucg acaccgggau cggaaugaca aaagcggauc      360

uuauuaauaa ccuggguacc aucgcuaagu cgggcacuaa ggccuucaug gaggcauugc      420

aggccggggc ugacauuuca augaucggac aguuuggcgu ugguuucuac agcgcauauc      480

ucguggccga aaaaguaaca gugauaacca agcauaauga ugacgagcag uacgcuuggg      540

aaaguuccgc cgggggaucu uuuacggucc gcacugauac cggcgagccc augggccgag      600

ggacaaaagu gauucugcac cugaaggaag accaaacuga guaucucgag gaacguagaa      660

ucaaagagau uguuaagaag cauagccagu ucaucggaua cccuaucacc uuauuugugg      720

aaaaagagag ggauaaggaa gucuccgacg acgaggcgga ggaaaaagag gauaaggaag      780

aggaaaaaga gaaggaggaa aaagagucag aagacaagcc agagauugag gaugugggua      840

gugacgaaga ggaagagaag aaagauggcg acaagaaaaa gaaaaagaag auaaaagaaa      900

aguauaucga ucaggaggag cugaacaaaa caaagcccau uuggacccgg aauccugacg      960

auaucacgaa cgaagaguac ggggaguucu acaaaagccu uacuaaugac ugggaagauc     1020

acuuggcagu aaagcauuuu ucuguugaag gacagcugga guuccgcgcc cuacucuuug     1080

ugccaagaag ggcucccuuc gaccuguucg agaaccggaa gaaaaagaau aacauaaaac     1140

uuuauguccg ccgaguguuu auuauggaca auugcgaaga acugaucccu gaauacuuga     1200

acuucaucag aggcgugguc gauuccgagg accucccacu gaacauuuca agggaaaugu     1260

uacaacagag caagauccug aaaguuauuc ggaagaaucu cgugaagaaa ugucuugagc     1320

uguuuacaga guuggccgaa gauaaggaga acuauaaaaa guucuacgaa caguuuagua     1380

aaaauauaaa gcuagguauc cacgaggacu cucaaaaccg uaaaaagcug uccgagcucc     1440

ugcgcuauua caccagcgca ucgggggaug aaaugguauc ucuuaaggac uauugcacua     1500

gaaugaaaga gaaucagaag cacauuuacu acaucacagg agaaaccaaa gaucaggugg     1560

cuaacuccgc cuucgucgag aggcugcgga agcauggcuu ggaagugauc uauaugauug     1620

agccgauaga cgaguacugu guucagcaac ucaaagaauu ugagggcaag acgcuggugu     1680

cagucaccaa ggaaggguua gagcugcccg aagaugagga ggagaaaaag aaacaggaag     1740

aaaagaaaac aaaguucgag aaucuaugca agaucaugaa agacauucuc gaaaagaaag     1800

uggagaaggu aguugugagu aaccgacugg ucacuagccc uuguugcauc gugaccucca     1860

cauauggaug gacugcgaau auggagcgca uuaugaaagc ccaggcacuu agagauaacu     1920

cuaccauggg uuacauggcu gccaagaagc acuuggaaau caauccagac cauagcauaa     1980

ucgagacacu gaggcagaaa gcugaagccg auaagaacga caaaucaguc aaggaccucg     2040

ugauucugcu uuaugagacc gcacuguuga guuccggcuu uagccucgag gauccccaaa     2100

cucacgccaa ucggaucuac cgcaugauua aacugggguu aggaaucgac gaagaugacc     2160

cuacggcuga ugacacaucu gcggcaguua ccgaggaaau gccaccccug gagggcgaug     2220

acgauacuuc aagaauggaa gagguggacu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  2939
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt3)

<400>  2939
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcuccaagcu ggauucuggc aaagggcucc acaucaaccu ugugcccaau aagcagaacc      120

aaacccugac aauugucgac acuagaauag gaaugacgaa aaccgauuug aucaauaacu      180

uagguacagu uacuaaguca ggcaccaaag ccuucaugga ggcucugcag gcagacgccg      240

auauuaguau gaucgggcau uuuggagugg gcuucuacag cgcguaucua guagcuaaga      300

aggugacagu cauuuccaaa cacaauaacg acgaacagua caccugggag ucuucggccg      360

gugggucauu uacugugagg acagaugaau gaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  2940
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt3)

<400>  2940
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggaagugca ccauggcgag gaagaggucg aaaccuucgc cuuucaggcu gagaucgcac      120

aacugaugag ccucauuaua aacacauucu acuccaauaa ggagaucuuu cuuagagaac      180

ugauuucuaa cgccucagac gcguuggaua aaaucaggua ugagaguuua acugacccua      240

gcaagcugga uuccgggaaa gaacuaaaga uugacaucau accaaauccg caggagcgga      300

cgcucacccu gguugauaca ggaaucggua ugacuaaagc ugaccuuauu aacaaucugg      360

gcaccaucgc caagucuggg acaaaggcau ucauggaggc cuugcaggcu ggagcagaua      420

uuucgaugau cggccaguuu gguguggggu ucuacucagc cuaucucgua gcugaaaaag      480

uggucgugau aaccaagcac aacgacgaug agcaauacgc cugggaaagc agugcgggag      540

gcuccuuuac uguucgcgca gaccauggcg agcccauugg gcgaggaaca aaagugaucc      600

ugcaccugaa ggaagaucag accgaguauc ucgaggaacg uagagucaaa gaggugguaa      660

agaagcauuc ucaguucauu gguuacccua ucacguuaua ucuggaaaaa gagagggaaa      720

aggagaucag cgacgaugag gccgaagagg aaaaaggcga gaaggaagag gaggacaaag      780

acgaugaaga gaagccaaaa auugaagacg uuggguccga ugaggaggac gauucaggaa      840

aggacaagaa aaagaaaacu aagaaaauaa aggaaaagua caucgaucag gaggaacuua      900

auaaaaccaa gcccauuugg acacggaacc cugacgauau cacucaagag gaauacggcg      960

aguuuuauaa aaguuugacc aaugacuggg aggaucaccu ggcugugaag cacuucagcg     1020

ucgaagguca gcuagaguuu cgcgcccucc uguucauacc aagaagggca cccuuugacc     1080

uuuucgaaaa caaaaagaag aaaaauaaca uuaagcugua cgugcggcgc guguucauca     1140

uggacucuug cgaugaguug aucccugaau aucucaauuu uauucgaggg gucguugacu     1200

ccgaggaucu gccauuaaac aucucaagag agaugcugca gcagagcaaa auucucaagg     1260

ugauaaggaa aaauaucgua aagaaguguc uugaacuguu cagugaguug gcugaagaca     1320

aagagaacua caagaaauuu uaugaagccu ucucuaagaa ccuaaaacug ggcauucaug     1380

aggauuccac aaaucggcgu cgccucagcg agcugcuuag auaccacacc ucgcaaucug     1440

gagacgaaau gacgucccug ucagaguaug ugaguaggau gaaggaaacu cagaaaagca     1500

ucuacuacau cacaggcgag uccaaggagc aggucgcgaa cucugccuuu guggaacggg     1560

uucgaaagcg cggguucgag guggucuaua ugaccgaacc gauugaugag uacugcgugc     1620

aacaguugaa agaauuugac ggaaagagcc ucguaucagu uacuaaagag ggucuggagu     1680

uacccgaaga ugaggaagag aagaaaaaga uggaagagag uaaggcaaaa uucgagaauc     1740

uguguaagcu aaugaaagaa auacucgaca agaaagugga gaaggucaca aucuccaaca     1800

gacuggugag cucuccuugc uguauuguca ccucaacgua uggcuggacc gcuaauaugg     1860

aaaggaucau gaaggcccag gcccuucggg auaacaguac aaugggguac augauggcua     1920

aaaagcauuu ggagauuaau ccagaccacc ccaucgugga aacucugcgc cagaaagcag     1980

aggccgauaa gaacgacaaa gcuguuaagg accucguggu acugcuuuuu gagaccgcgc     2040

uguugagcuc cggauucucu cucgaagauc cucaaacaca cucgaauaga auauauagga     2100

ugaucaagcu gggcuuaggu auugacgagg augaagucgc agccgaggag ccaaacgcug     2160

ccgugcccga cgaaaucccg ccucuggagg gggaugaaga cgcaagccgu auggaggaag     2220

uugauugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  2941
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt3)

<400>  2941
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagag       60

cccugugggu gcucggccuu ugcugugucc uguugaccuu cgggagcguu agggcugacg      120

augaggugga cguagaugga acaguggaag aggacuuagg uaagucccgg gaaggcucuc      180

gcacugauga cgaggucgug cagcgagaag aggaggcaau ccaacuggau gggcuaaacg      240

ccucacagau ucgugaacuc agagagaaaa gugaaaaguu ugcguuccag gcugagguua      300

auaggaugau gaaacugaua aucaacagcc uuuacaagaa uaaagagauu uuucugcggg      360

aauugaucuc caacgccucu gacgcacucg auaagauucg ccugaucucg cugacggacg      420

agaaugcccu cucaggaaac gaagaguuaa ccgugaagau aaaaugcgau aaggagaaaa      480

aucugcuuca cgucacagac acuggcgugg guaugaccag agaggaguug guaaagaacc      540

uggggacaau cgcuaaaagc ggaaccagug aguuccuaaa uaagaugacu gaagcacagg      600

aagauggcca auccacaucu gagcucauug gccaguuugg gguuggauuc uauagcgccu      660

uucugguggc ugacaagguc aucgugaccu ccaaacauaa caaugacacg cagcacauuu      720

gggaaucaga uaguaacgag uucagcguga ucgccgaccc cagggguaau acucuuggcc      780

gggggaccac aauaacucug gucuugaagg aggaagcguc ugauuaccuc gagcuggaca      840

ccauuaaaaa cuuaguuaag aaauauuccc aguuuaucaa uuucccuauu uacguguggu      900

caagcaagac agaaaccgua gaggaaccaa uggaggagga agaggcagcc aaagaagaga      960

aggaggaaag ugaugacgag gcugccgugg aagaggaaga ggaggaaaag aaaccgaaga     1020

cgaaaaaggu cgagaaaacu gugugggauu gggaacugau gaacgacauc aagcccaucu     1080

ggcaacgccc uucuaaggag guugaagagg augaguauaa agcauuuuac aaguccuuca     1140

gcaaagaauc ggacgaucca auggcuuaua uucauuuuac agccgaggga gaagugaccu     1200

ucaagucuau acucuucguc cccacuuccg cgccucgagg ccuuuuugac gaguacggua     1260

guaaaaaguc agacuacauc aagcuguaug ugagaagggu auucauuaca gaugacuuuc     1320

acgauaugau gccaaaauac uugaacuucg uuaagggggu ggucgacagc gaugaccuac     1380

cccugaaugu gucccgggaa acccuccagc agcauaaacu gcuuaagguc auccguaaaa     1440

agcuggugcg caagacguug gauaugauua aaaagauagc cgacgauaaa uauaacgaca     1500

ccuuuuggaa ggaguucgga acaaauauca aacucggcgu uaucgaggau cacucuaaca     1560

gaacuaggcu ggcaaaguua cugcgguuuc agagcucaca ccauccuacc gacauuacaa     1620

gucuagauca auacguggaa cgaaugaaag agaagcagga caagaucuau uucauggcug     1680

gcuccagccg caaagaagcc gagucuucac cauuuguaga gagacuccug aagaaagggu     1740

acgaagucau uuaucuuacu gagccggugg acgaauacug uauacaggcu uugcccgagu     1800

ucgauggaaa gagguuucaa aauguugcca aagaaggugu gaaguucgac gagagugaga     1860

agaccaaaga aagccgggag gcagucgaaa aggaguuuga accucugcuc aacuggauga     1920

aagauaaggc ccugaaagac aagaucgaga aggcuguggu aucccagcgc cuuacagagu     1980

cuccaugcgc gcugguggca ucgcaguacg gcuggagcgg gaauauggaa agaauuauga     2040

aagcccaggc uuaucaaacc ggaaaggaua ucuccacuaa cuacuaugcc ucacagaaaa     2100

agacguucga gaucaauccc aggcacccuu ugauucguga caugcuccgg cgaauaaaag     2160

aagaugagga cgauaagaca guucuggacu uagcagucgu gcuguucgaa accgccacuc     2220

uaagaagugg cuaccuccug ccagauacca aggcuuaugg ugacaggauc gagcgcaugc     2280

uucgguuguc ucugaacauu gaucccgacg ccaaagugga ggaagaaccg gaagaggagc     2340

cugaagagac agcagaagac accacugagg auacagaaca ggacgaggau gaggaaaugg     2400

acgucgggac ggaugaggaa gaggaaaccg cgaaggagag cacugcugag aaagacgaac     2460

ucugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  2942
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt3)

<400>  2942
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

gagagcugag ggcucuccuu cuguggggcc ggcgcuugcg acccuuacug cgugcuccug      120

cccuagcggc ugugccaggg ggaaagccga uccucugccc cagaaggacc acagcccagc      180

uggguccucg gcgcaaccca gcauggagcc uucaagccgg cagacuguuc uccacucaga      240

cggcugaaga caaagaggaa cccuugcacu cuauuauauc aaguaccgag agcguccagg      300

gguccacauc uaagcaugaa uuucaggcag agacuaaaaa gcuccuggau aucguugcca      360

ggucgcugua cucagagaaa gaaguguuca uucgggagcu caucagcaau gcuagugacg      420

ccuuagaaaa gcugcgccac aagcuaguau ccgauggaca agcguugccu gagauggaga      480

uucaucugca gaccaacgca gaaaaaggca caaucaccau acaggacacu gguaucggga      540

ugacacagga ggaacuugug ucuaaucucg gaaccauugc ccgaagcggc uccaaggcuu      600

uucuggaugc ccuucaaaac caggcagagg cuucaaguaa aaucauuggc caguucgggg      660

ucggauuuua uagcgccuuc augguggcgg acagaguuga aguguacucu agguccgccg      720

caccagguuc acugggcuau cagugguuga gcgaugggag uggagucuuu gagaucgcug      780

aggccucugg cgugcggacg gguacuaaga uaauuaucca ccucaaaucc gacuguaagg      840

aauuuagcuc ggaggcucgu guacgcgaug uugugaccaa guacucuaau uuugucuccu      900

ucccccugua uuuaaacggg agaaggauga auacacugca agccauuugg augauggacc      960

cuaaagaugu gcgggaaugg cagcaugagg aauuuuaccg auauguggca caggcccacg     1020

acaagccacg cuacacucuc cacuacaaaa ccgaugcucc gcuuaacauc agaucaaucu     1080

ucuauguccc cgacaugaag ccuaguaugu uugacguuag cagggagcug ggauccucug     1140

uggcguugua cagccggaaa guacuaauuc aaacaaaggc aaccgauaua cugccaaaau     1200

ggcuccgcuu caucagaggc guggucgacu cagaggauau uccccugaau cuuaguaggg     1260

aacuguugca ggaguccgcc cucauccgua agcugcggga cguguuacag cagcgacuga     1320

uaaaguucuu uauugaucaa agcaaaaagg acgcugaaaa auaugccaag uucuuugagg     1380

auuacggccu auucaugaga gaagggaucg uuacggcaac ugagcaggag gugaaagaag     1440

acaucgccaa gcuccugagg uaugagucuu cagcacuucc uaguggacag uugacaagcc     1500

uguccgaaua cgccucucgc augcgggcag guaccagaaa cauuuauuac cucugcgcgc     1560

caaauaggca ucuggcugag cacucgcccu acuaugaggc caugaagaaa aaggauacug     1620

aaguccuuuu cuguuucgag caguuugacg aacugacauu gcuccaucug cgcgaguucg     1680

auaaaaagaa auuaaucagc guggaaaccg acauuguagu ugaccacuac aaggaggaga     1740

aguuugaaga ucgauccccg gcagccgagu gccugucaga aaaagagacg gaagaacuaa     1800

uggcuuggau gcggaacgug cucggcaguc gugucaccaa ugugaagguc acacugagac     1860

uugacacuca cccugccaug gugaccguuu uggagauggg ggcagcuagg cauuuccugc     1920

gcaugcaaca gcucgccaaa acacaggagg agcgggcgca gcuguuacaa cccacucugg     1980

aaauaaaccc aagacacgcc cuuaucaaga aauugaauca gcucagggcu ucugagccug     2040

gacuggcaca gcuacuggug gaucagauuu augaaaacgc caugaucgcu gccggccucg     2100

uagacgaucc ccgagcaaug gucggucgcc ugaacgagcu uuuggugaag gcgcuggagc     2160

ggcauugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  2943
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt3)

<400>  2943
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

agaucagcuc ccugcccacc caacucuuca aaugcuguuu uugcgacuuc cuuaagguga      120

aaaugcacac aaugucuuca agucaucugu uuuacuuggc cuuaugucug cuaacuuuca      180

cgagcuccgc uaccgcaggg ccugagacac ucugcggagc cgaacugguc gaugcgcuuc      240

aguuuguuug uggugacaga ggcuucuauu uuaacaagcc aacuggguac ggaucuucgu      300

caaggcgggc uccgcagacc ggcauugugg augagugcug uuuccgcagc ugcgaccugc      360

gacguuugga aauguauugu gcaccccuca aaccugccaa gagugccaga uccguaaggg      420

cucagcggca cacagauaug ccaaagaccc agaaagaggu gcaucugaag aaugcaucuc      480

gcgguagcgc cgggaacaaa aauuacagaa ugugaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  2944
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt3)

<400>  2944
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

uccccauggg aaagagcaug cuggugcucc uuaccuuccu ggccuuugcu uccugcugua      120

uugcagccua cagaccuucu gagacauugu gcggggguga auuagucgac acucugcagu      180

ucguuugugg cgauaggggg uuuuauuucu cacggccagc gagucgcgug agccgacguu      240

ccagaggaau aguagaggaa ugcuguuuua ggucuugcga ccuagcucuc cuggagacgu      300

acugugccac cccggcaaaa ucggaacggg augugucaac acccccuacu guccuuccag      360

acaacuuccc ccgcuauccu gugggcaagu uuuuccaaua cgauaccugg aaacagagca      420

cacagagacu gaggcggggu uugccagccc uccugcgcgc ucgaagaggg cacguucugg      480

caaaggagcu cgaggccuuu agggaagcua aacggcaucg ucccuuaauc gcccugccua      540

cccaggaccc agcgcacgga ggcgcaccgc ccgagauggc caguaaucgc aagugaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  2945
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt3)

<400>  2945
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaca       60

gcuucuccac cucugccuuu ggccccgugg cuuucucacu ggggcuccuu cuggucuugc      120

cugcagccuu uccagcgccg guucccccug gagaggacag uaaggaugug gcugccccac      180

acagacagcc cuuaacaagc uccgaaagga ucgacaaaca aauucgguac auacuggaug      240

guaucucugc acuacgcaag gagacuugca auaaaucgaa caugugugaa ucaagcaagg      300

aggcccucgc ugaaaauaac cugaaucuuc cuaaaauggc agagaaggac ggcugcuucc      360

agaguggguu uaacgaggaa acgugucugg uaaagauuau caccggauug cucgaguucg      420

aaguguaucu ggaguaccug cagaaucgau uugaguccuc ugaagaacag gcccgugcug      480

uccaaaugag cacaaaagug cucauucagu ucuuacagaa gaaagccaag aaccuggaug      540

cgaucacuac cccagacccc acaaccaaug caucccuuuu gacuaaacug caggcccaaa      600

accaguggcu acaggauaug acaacccauc ucauacugag aucauuuaag gaguuccuuc      660

agaguagccu gagggcuuug cggcaaaugu gaggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  2946
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt3)

<400>  2946
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugcucuggcu uagaggcuuc cuguuggcca gcugcuggau cauugugagg uccucuccua      120

ccccaggguc agagggacac agugcugcac cggacugucc cagcugcgcc uuagcggcuc      180

ugccuaagga ugucccaaac ucccagcccg aaaugguuga ggccgugaaa aagcauauac      240

uaaauaugcu ccaccugaaa aagcggccug acguaacaca accagugccc aaagcagccc      300

uucugaacgc uauccgcaag uugcaugucg guaagguggg cgaaaauggg uacguugaga      360

uugaagauga caucggacga cgugcagaga ugaacgagcu cauggaacag acuucugaga      420

uuaucacguu ugccgaaucg ggcaccgcua gaaaaacacu gcacuucgag auaucaaagg      480

aggguagcga ucugagugug gucgaaaggg ccgaggugug gcucuuuuua aaaguaccua      540

aggcgaaucg gacucgcacc aaaguuacaa ucagacuguu ccagcagcaa aagcauccac      600

aggggucccu ugacaccgga gaagaggcag aagagguggg cuugaagggc gagaggucug      660

aacugcuacu cagcgagaaa gucguggaug cccggaaguc cacuuggcac guguuuccgg      720

ucucaaguag cauucagcgc cugcuugacc aggggaaauc uucccuggau guucgaaucg      780

cuugugaaca augccaggag ucaggagcca gcuuggugcu ccuggguaag aaaaagaaaa      840

aggaagagga gggcgaaggg aagaaaaagg gaggcgguga agggggagca ggcgcugacg      900

aggagaaaga acagagucac agacccuucu uaaugcugca ggccaggcaa ucugaggauc      960

auccucaccg gcgucgcaga aggggccucg agugugacgg gaagguaaac auuugcugua     1020

aaaagcaguu uuucgugucc uuuaaggaua ucggauggaa ugacuggaua auugcgccaa     1080

gcgguuauca ugccaacuac ugcgaaggcg agugucccuc gcacaucgca gggacaucug     1140

gauccucacu uaguuuccac agcaccguca uuaaucauua ucggaugcga ggccacuccc     1200

cuuuugcuaa ccugaaaucu ugcugugugc caacgaaguu gcgccccaug agcaugcuau     1260

acuaugacga uggucagaau aucaucaaaa aggacauuca aaacaugaua guugaagagu     1320

gcgggugcuc augaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  2947
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt3)

<400>  2947
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacg       60

gccugcccgg gagagcccuc ggagcugcau gccuucuguu guuagccgcg gguuggcugg      120

gcccugaggc uugggggagc ccaaccccgc ccccuacacc agccgcaccc ccuccacccc      180

cuccaccggg aucccccggc gguucucagg auacuuguac gucaugcggg ggauucaggc      240

ggccugagga acuaggccgc guggacggcg auuuucucga agccgucaag cgacacaucc      300

ugagucgucu ucaaaugaga gggaggccaa acauuaccca ugcuguuccc aaagcagcca      360

uggugacagc ucugcggaag uugcacgccg gaaaaguacg cgaggacggu agaguggaaa      420

uaccucaucu cgauggccac gcgagcccag gggcagacgg acaggagagg gucuccgaga      480

ucauuucuuu cgccgaaacu gauggccugg cuucgucacg ggugcgccug uacuuuuuca      540

ucagcaauga ggguaaccag aaucucuuug uugugcaggc caguuuaugg cuguaucuua      600

aguugcugcc cuacguccua gaaaaagggu cccgaagaaa ggugagggua aagguuuauu      660

uccaagagca gggacauggc gaccggugga acauggugga gaaacguguc gaucucaagc      720

gcucuggcug gcacaccuuu ccgcugacag aagcaauuca ggcucuuuuc gagagagggg      780

aaaggcggcu gaauuuggac gugcagugug auagcugcca agagcucgcc guggucccug      840

uuuuugugga ccccggagaa gagucccacc gaccauucgu agugguccag gcgcgccugg      900

gugauucaag acauaggauc cggaaacgcg gcuuagagug ugacgggaga accaaccugu      960

gcuguaggca gcaguuuuuc auagacuuuc gucucaucgg auggaaugau uggauuaucg     1020

ccccuacugg cuacuauggu aacuacugcg aagggaguug ucccgcauau cuugcuggcg     1080

ugccaggaag cgccucuucc uuccacacag cuguugugaa ucaauaccgg augcgaggcc     1140

ugaaccccgg gaccgucaau ucaugcugua uuccuacgaa guugagcacu augaguaugc     1200

uauacuucga cgaugaguau aacaucguga aaagagacgu accaaauaug auaguugaag     1260

agugcggaug cgccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  2948
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt3)

<400>  2948
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ugagagugcu ccuucugacc gcuuugacau uaugccacgg cuucaaccug gacacugaga      120

augcaaugac guuucaggaa aacgccaggg gguucggaca aagcgucguu cagcuacagg      180

guucccgggu gguagugggc gcgccccagg agaucgucgc ugccaaucaa cgcgggucuc      240

ucuaccagug ugauuauuca accggaaguu gcgaaccuau ucgacugcaa gugccaguug      300

aggcagugaa caugagccuu ggccuguccu uggccgcuac aacuucuccg ccccagcucc      360

uggcaugugg uccuaccguc caucaaacau gcucggaaaa uaccuacgug aaggggcugu      420

guuuucucuu cggaucaaac uuacgucagc agccacagaa auuucccgag gcccugagag      480

gcugcccuca agaggacagc gauauagcuu uccuuaucga cggcaguggg uccauuaucc      540

cacacgauuu uaggcggaug aaggaguucg uaucuacugu uauggaacag uugaaaaaga      600

gcaaaacacu guuuucccua augcaguauu cagaagaguu ccgcauucau uuuaccuuca      660

aggaguuuca aaauaacccc aauccuagaa gucucgugaa gccaaucacg cagcugcuug      720

gaaggacuca caccgccaca gguauacgga aagucgugcg cgaacuguuc aacaucacua      780

auggcgcgcg aaagaacgca uucaaaauuu ugguggucau caccgacggg gagaaguuug      840

gagauccgcu cggcuacgaa gacguuauuc ccgaggccga uagagaaggu gugaucaggu      900

auguaauagg ggugggagac gcuuuccgga gcgagaaauc ucgucaggag cugaauacaa      960

uugccuccaa gccuccacgc gaucaugucu uucaggugaa caauuucgaa gcauuaaaga     1020

ccauccaaaa ccagcugaga gagaaaauuu uugcuaucga aggcacgcag acuggcucaa     1080

gcaguucuuu cgagcacgaa augucccagg agggguuuag cgccgcgauc acaucgaacg     1140

gaccccuccu uucuaccguu gguuccuacg acugggccgg cgggguguuc cuguauacuu     1200

caaaggagaa aaguacauuu auuaauauga ccagggucga uagcgacaug aacgacgcau     1260

acuugggaua cgcugccgcu auaauccuac ggaaucgagu gcaaucccug guacucggcg     1320

ccccucgcua ucagcacauu ggucugguug caauguucag acagaacacg gggauguggg     1380

aaucuaaugc caacgugaag ggcacccaga ucggagcuua cuuuggcgcg agccuuuguu     1440

cagucgaugu ggacaguaau ggguccacag aucuggucuu gauaggagca ccacauuauu     1500

acgagcaaac uagggguggc caggugagcg uuugcccccu cccgcggggg cgcgccagau     1560

ggcaguguga cgcugugcug uauggagaac agggccaacc uugggguagg uucggggccg     1620

cauuaaccgu acugggcgau gucaacggag acaaacuaac agauguggcc auuggcgcuc     1680

ccggggagga agacaaucgu ggagccguuu accucuuuca cgguacuucu ggcucaggga     1740

ucaguccaag ccauucccag cggaucgcag gaucuaagcu gucgccucga cuucaguauu     1800

ucggccagag cuuguccggu gggcaggauc ugaccaugga cggccucgug gaucugacag     1860

ucggagcgca gggccacgug cuucuguuga gaucacagcc cguacucagg gugaaagcua     1920

uuauggaguu caacccacgc gagguugccc ggaaugucuu ugaaugcaac gaccaagugg     1980

ugaaggggaa ggaggcagga gaagucagag uuugucugca cgugcagaaa aguaccaggg     2040

accgcuuacg agagggccag auccagucug ugguaacuua cgaucuggcc cuagacagcg     2100

gucggcccca uucccgugcu gucuucaaug agacgaagaa cucaacaaga aggcaaaccc     2160

aggugcucgg gcugacucag accugcgaaa cacuuaaauu gcagcugccu aauugcauug     2220

aggauccagu uagcccgaua gugcuccgcc ugaacuuuuc uuuagucgga accccucugu     2280

ccgccuucgg caaccuucgg ccuguguugg cagaagacgc ucaaagacuc uuuacugccc     2340

uguucccauu ugagaagaau ugugguaacg auaauaucug ccaggacgau cuaaguauua     2400

cauucagcuu uaugucucug gacugucucg uugugggcgg gcccagggag uucaacguaa     2460

cggucaccgu gcgaaaugau ggagaagacu ccuaccgcac ucaggugaca uuuuucuuuc     2520

cucuggaucu uucauaucgg aaagucagua ccuugcaaaa ccagagaagc cagaggucgu     2580

ggcgucuggc gugcgagucc gccucuagca cagaaguuuc aggcgcuuua aagaguacuu     2640

ccuguucuau caaucaccca aucuuccccg agaacagcga agugaccuuc aauauuacgu     2700

uugacguaga uuccaaggca ucacucggga acaaacugcu ucugaaggcc aaugugacca     2760

gcgagaacaa uaugccgcgc acaaacaaaa cugaguucca guuggaacuc ccugucaagu     2820

acgcugugua uaugguugug accagucaug gagucucuac aaaauaccug aauuuuacug     2880

ccuccgagaa caccagccgg gugaugcaac accaguauca gguuucgaac cuaggccaga     2940

gaucacugcc aauaucucuc guguuccugg uccccguaag gcuuaaucaa acggugaucu     3000

gggaccgacc ucagguuaca uuuagugaaa acuuguccuc uaccugccau acuaaggagc     3060

ggcugcccag ccacagcgac uucuuagcag aacuccgcaa ggcgccagug gucaauuguu     3120

ccauugccgu gugccagaga auccagugug auauucccuu uuucgguauc caagaggaau     3180

uuaacgcuac acugaaaggg aaucuuucau ucgacuggua cauaaagacc agucacaacc     3240

aucugcuaau cguaagcacu gccgagauuc ucuuuaauga uucuguguuc acccuguugc     3300

ccggacaggg cgcauucguc aggucccaga cagagacgaa aguugaacca uuugaggugc     3360

cgaacccucu gcccuuaauc guggguucaa gugucggcgg gcuccugcuu cuggcuuuga     3420

uuaccgccgc acucuauaag cugggauucu uuaaacggca guacaaggac augaugagcg     3480

aaggcgggcc acccggagcc gagccucaau gaggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  2949
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt3)

<400>  2949
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguuca       60

gccugaagac ccuccccuuu cuucuguugu uacacgugca gaucuccaaa gccuucccug      120

ucucuucaaa ggagaaaaac acaaagacug uucaagacua ccuggaaaaa uuuuaucagc      180

uaccaaguaa ucaguaccag agcacgagaa agaacggcac caaugugauu guagagaagc      240

ucaaagaaau gcaaagguuc uuugggcuga acgugacagg aaagccgaau gaggaaacuc      300

uugauaugau gaaaaagccc cggugcggug ucccugacuc cggcggguuc augcugaccc      360

caggaaaccc caaaugggag cgcacaaauu ugaccuaucg aauacguaac uacacuccuc      420

agcucucuga ggcugaagug gagagagcaa ucaaggaugc cuuugaacug uggucgguug      480

cgucaccacu gauuuucaca aggaucagcc agggcgaggc ugacauuaau aucgccuuuu      540

aucagcggga ucauggugac aacagucccu ucgaugggcc uaauggaaua cucgcacacg      600

ccuuucaacc aggccagggc aucgggggag acgcucauuu cgaugcagag gaaaccugga      660

cgaacacuuc cgccaauuac aacuuauuuc ugguggcugc ccacgaguuc ggucauucuc      720

uuggcuuggc gcacagcucc gacccggggg cacugaugua ucccaauuac gccuuccgcg      780

aaaccucaaa cuacagucua ccucaggaug acauugaugg aauccaggcu auuuauggcc      840

ucagcucuaa cccaauccaa cccacagguc cuuccacucc aaagcccugu gacccgucac      900

ugaccuuuga cgccauaaca acccuuagag gggagauucu guucuuuaaa gauagguacu      960

ucuggcggcg ccacccucag uugcagcgag ucgaaaugaa uuuuaucagc cucuucuggc     1020

ccagucugcc aacgggcauu caagcagcuu augaggacuu ugauagagac uuaaucuucc     1080

uguuuaaggg aaaccaguac ugggcccucu cuggcuauga uauccuucag ggguacccua     1140

aagacauuuc caauuaugga uuccccagcu cggugcaggc gauagaugcc gcaguauuuu     1200

acaggucuaa gacuuacuuc uuuguuaacg accaauucug gcgguaugau aaucagcguc     1260

aguucaugga gccagguuac cccaaaucca ucucaggcgc uuuuccuggg auugaaagua     1320

agguggacgc cgucuuccag caagagcacu uuuuccaugu guuuagcgga ccacgcuauu     1380

acgcuuucga ucugaucgcc cagagaguga caagggucgc acggggcaac aaaugguuga     1440

auugccgaua ugguugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  2950
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt3)

<400>  2950
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

uguggcagcc ccucgugcuu guccuguugg uuuuaggcug cuguuucgcc gcuccuagac      120

aaaggcaguc cacccuggug cuauuuccag gggaccuccg gacaaaccug acugaucgcc      180

agcuugcaga ggaauaccug uaucgauacg gauauacgcg uguagccgag augagaggug      240

aaucuaaauc auugggcccg gcgcuccugc ugcuccagaa acaauuaagu cugcccgaga      300

ccggggaacu ugacagcgcu acauugaagg ccaugaggac uccucggugc ggagugccag      360

aucugggccg cuuccagacc uuugagggug accuaaaaug gcaccaucac aauaucacau      420

acuggauuca gaacuauucc gaggaucucc ccagagcagu cauagacgau gccuucgcua      480

gggcauuugc ccuguggucu gcugugaccc cucuuacuuu cacacggguu uacucgcgcg      540

acgccgauau cgugauucag uuuggggucg cggaacaugg agacggcuau ccauucgaug      600

gcaaggacgg gcuguuggca cacgccuuuc ccccuggacc agguauccaa ggcgaugcuc      660

auuucgacga cgaugagcuc uggucacugg ggaaaggagu gguaguuccg acccgauuug      720

gcaaugccga cggugcagcu ugucacuucc ccuuuauuuu cgaagggaga agcuacagug      780

ccugcacgac ugauggaagg uccgacggcu uaccuuggug uucuaccaca gcgaacuacg      840

auacugacga ucgguucggc uuuugcccaa gcgagcgucu guauacccag gacgggaaug      900

ccgauggaaa gcccugucag uucccuuuua ucuuccaggg ucaauccuac ucagcaugca      960

caaccgacgg ccgcagugau ggguauagau ggugugcuac gacugccaac uacgacaggg     1020

acaagcucuu uggauucugc ccaacacggg cugauagcac cgugaugggc gguaauucug     1080

ccggggagcu uugugucuuu cccuucacuu uucugggcaa agaauauucc acaugcaccu     1140

cagagggacg aggcgacggg cgcuuguggu gcgcaacgac cagcaacuuc gauagugaca     1200

agaaaugggg auuuuguccg gaucaggguu acucucuauu ccugguggcc gcucacgaau     1260

uuggccaugc gcucgggcug gaccacucca gcgugccuga ggcacuuaug uaucccaugu     1320

acagauucac agaaggacca ccucugcaua aggaugacgu caauggcaua aggcacuugu     1380

acgguccccg gccagagccc gagccucgcc caccgacuac cacaacuccc cagccuaccg     1440

ccccacccac aguuugcccu accgggccac ccacugugca cccgucggaa agaccuacgg     1500

cuggcccaac aggacccccu ucugccggcc ccaccgggcc accuacugca ggacccucca     1560

ccgccacaac cguaccacuc ucaccggugg augacgcuug uaacgucaau aucuucgaug     1620

ccauugcaga gaucgguaac caacuguauu uauuuaaaga cggcaaguac uggagguuca     1680

gugaagggcg uggaagccgg ccucagggcc ccuuucugau ugcggauaag uggccagcuc     1740

uaccccgaaa acucgacucc guguucgagg aaagacuguc uaagaaauug uuuuucuuua     1800

gcgguaggca gguuugggug uauacugggg ccucaguccu uggcccucgc cggcuggaca     1860

agcucggacu gggcgcagau guggcccagg uaacaggggc ucuuagaagu ggaaggggca     1920

aaaugcuguu guucuccggu cgccgacucu ggcgguuuga cguuaaggcc caaauggugg     1980

auccacguag cgcaucugag gucgacagaa uguuccccgg ggugccucug gauacgcaug     2040

acgucuuuca guacagggag aaggcuuauu ucugccagga ucgcuuuuac uggcgggugu     2100

caaguagaag cgaauuaaau cagguugacc aagugggaua uguaaccuac gauauccugc     2160

aguguccgga ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  2951
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt3)

<400>  2951
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ccggcgugcu ggccgcuuuc cucuuucuua gcuggaccca uugcagagca cugccuuugc      120

cauccggggg agacgaggau gacuuaucug aagaggaucu gcaguucgcc gaaagguacc      180

uacggucaua uuaccacccg acaaaccucg cggguauccu gaaggagaau gcugccagua      240

gcaugacuga acgccuucga gagaugcaau ccuuuuucgg ccuggagguc acggggaaau      300

uggacgauaa cacccucgac guuaugaaga aaccccguug uggagugccu gauguaggcg      360

aauauaaugu guuuccaaga acacugaagu ggucuaaaau gaaccugacu uacaggauug      420

ucaauuauac ccccgacaug acacauucgg agguggaaaa ggcauucaag aaagccuuua      480

agguuugguc agaugugacc ccucucaacu ucacucgguu acacgacggu auagcugaua      540

ucaugauuag cuuugggauc aaagagcaug gagacuucua cccauuugau ggccccagug      600

gccugcuugc acacgccuuc ccuccagggc cgaauuaugg aggugacgcu cacuuugacg      660

augacgagac auggaccucc ucuagcaagg gcuacaacuu guuccugguc gccgcgcaug      720

aguucgggca cucccuagga cucgaucauu caaaagaccc cggcgcacug auguuuccua      780

uuuacacgua uacugguaag agucacuuca ugcuuccaga ugacgaugug caggggaucc      840

agagccugua cggacccggc gacgaagauc cuaauccaaa gcaccccaaa accccggaca      900

agugcgaucc uucuuugucc cucgacgcca uaacaucacu gcgcggcgaa acuaugaucu      960

uuaaagacag auucuuuugg agguuacauc cccagcaagu agaugcugag cuguuccuca     1020

ccaagagcuu uuggccagaa cuuccuaacc ggauugacgc cgcauaugag caccccaguc     1080

augaucugau cuucauuuuu cgcgggcgaa aauucugggc uuugaaugga uacgacaucc     1140

uagaggguua uccaaagaaa auaucugaac ugggccuccc caaggagguu aagaaaauuu     1200

ccgccgcggu gcacuuugaa gauacaggga agacccugcu uuucagcgga aaccaggucu     1260

ggagauacga cgauacgaau cauaucaugg acaaagauua uccuaggcug auugaggaag     1320

acuuuccagg caucggugau aagguggacg ccguguacga gaaaaacggg uacaucuauu     1380

ucuucaaugg cccgauucag uuugaguacu cgauaugguc uaaccggauc guccguguua     1440

ugcccgcaaa cuccauuuug ugguguugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  2952
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt3)

<400>  2952
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

cccccaacac aacugaagac uacgauacga ccacagaguu cgacuauggc gaugccacuc      120

cuugccagaa ggugaaugaa agagcuuuug gggcacaacu gcucccaccg cuuuacagcc      180

uggucuucgu uaucggauug guggguaaca uuuuaguagu gcugguccua gugcaguaua      240

aaaggcucaa gaauaugacc uccauauacc ugcuuaaccu ggccaucucu gacuugcucu      300

uucuguucac acugcccuuu uggauugauu auaaacucaa ggacgauugg guuuucggcg      360

acgcgaugug uaaaaucuua ucaggguuuu acuauaccgg acuguacagu gagauuuucu      420

uuaucauacu uuugacuauc gaucgguacc uggcuauugu gcacgccguc uucgcacuac      480

gcgcccgaac agugaccuuu ggcguaauca cgagcauuau cauaugggcu cucgcaauuc      540

uggccuccau gccuggucuu uauuucucua agacucagug ggaauuuacc caucacacau      600

gcucgcugca uuucccacac gagucauugc gugaguggaa acucuuccag gcucugaagu      660

uaaaucuguu ugggcucguu cuuccccugu uggugaugau cauuuguuac acuggaauca      720

ucaagauucu acugagaagg ccuaacgaga aaaagagcaa agccguccgg cucauauucg      780

ugaucaugau uaucuuuuuc cuguuuugga ccccauauaa ucuuacaaua cugauuagug      840

uguuccaaga cuuuuuguuc acccaugaau gcgaacaguc ccgccaccuc gaucuggcgg      900

uccagguuac ggaggugauc gcauacacuc acuguugcgu aaaccccgug aucuaugccu      960

uugucggcga gagauucagg aaguacuuac ggcagcuguu ucaucgccga guggcuguuc     1020

accuagugaa guggcucccu uuccugucug ucgacagacu ugaaagggug agcuccacau     1080

caccaaguac cggcgagcau gaauugagcg ccggguuuug aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  2953
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt3)

<400>  2953
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagaa       60

cccuggccug ccuccuucug uugggaugug gguacuuagc ucacgugcug gcagaggaag      120

ccgagauccc cagggaaguc auugagcggc uagcgcgcag ccagauacau uccauccgag      180

accuccaacg ucugcuugaa auugauucug uuggaucaga ggacagucug gauacuagcu      240

ugagagcuca cggugugcau gccacaaagc acguaccuga gaaaaggcca cucccgaucc      300

ggcgcaagag auccauugaa gaggcagugc ccgccgucug caaaacgagg accgugaucu      360

augaaauacc ucggucucag guugacccaa caucggcuaa cuuccugauc uggcccccuu      420

guguggaggu caagcgcugc acuggcuguu gcaauaccuc aagcgugaaa ugucagccaa      480

gucgaguaca ucacagaucc guuaaggugg caaaggucga guacgugagg aaaaagccca      540

aacugaagga agugcagguc cggcucgagg aacacuuaga gugcgccugu gcuacaaccu      600

cucugaaccc ugauuaucgu gaagaggaca cugggcgccc aagagagagc ggcaaaaaga      660

ggaagcggaa acgacuuaag ccgacaugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  2954
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt3)

<400>  2954
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaca       60

gaugcugggc ccuguuccuc agccuuuguu gcuaccugag guuggugucc gcugagggcg      120

accccauccc ugaagaguua uaugaaaugc ugucugauca cucaauucgg aguuuugacg      180

aucuacagcg ccuccugcau ggggacccag gagaggaaga uggugcagag cuugaccuga      240

auaugacccg aagccacucc ggcggggagu uggaaucucu cgcccgugga agaaggucgc      300

ugggcucacu gacaauagcg gagccggcua ugaucgccga auguaagacu cggacggagg      360

ucuucgagau uagccgcaga cucaucgaua ggaccaacgc aaacuuuuua guuuggcccc      420

cuugcgugga aguacaacgg uguagugguu gcuguaauaa ucgcaacgug cagugccgac      480

caacacaggu ccagcugaga cccgugcaag uuaggaaaau ugagaucgug cggaagaaac      540

cuauauucaa gaaagccacu gucacccuug aagaccauuu ggcuuguaag ugcgagacag      600

uggcagccgc ucguccagua acccgcuccc ccgggggauc ucaggaacag agagccaaga      660

cuccucagac aaggguuacc auccggacgg ugcgaguccg cagaccaccg aaaggcaagc      720

acaggaaauu uaagcauacu cacgauaaaa ccgcgcugaa ggagacacua ggcgcaugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  2955
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt3)

<400>  2955
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

uguucggccu ccuucuguug accuccgccu uagcugggca gagacaagga acacaggcag      120

agucuaaccu gucaaguaag uuucaguuca gcuccaauaa agaacagaac ggugugcaag      180

acccccagca cgagaggauc auuacugucu cuacgaaugg cucgauacau ucaccucggu      240

uuccacacac cuacccgcgc aacacaguuc uaguguggcg acucguagcc guggaagaga      300

augucuggau ccagcugacu uucgaugaac guuuugggcu ugaggacccc gaggaugaca      360

uuugcaagua ugauuucgug gaaguugagg aaccuagcga cggaaccauc cugggcagau      420

ggugugguag ugggacagug ccaggaaaac agauuuccaa gggcaaccaa aucaggauac      480

gguuugucuc ugaugaguac uuccccagcg agccuggcuu uugcauccau uauaauauug      540

ugaugccaca guucaccgaa gcgguauccc ccucaguuuu gccuccaagu gcucucccgc      600

uggaccugcu caacaaugcc aucacugcau uuagcacauu agaggaucug auucgcuacc      660

uugaacccga gagauggcag uuggaccugg aagaucuaua uaggccuacc uggcagcucc      720

uggggaaagc cuucguguuu ggacggaagu cucgcgucgu ggaccuuaac cuguugacgg      780

aggaggugcg acucuacucc uguacuccaa gaaauuucuc agucagcauc agggaggaac      840

ugaagcggac cgauacaaua uucuggcccg guugcuuacu gguuaaacgu uguggcggga      900

acugcgcuug uugccuccac aauuguaacg aaugccaaug ugugccuagu aagguaacua      960

aaaaguauca ugaggugcuu cagcugcgcc caaaaaccgg agucagaggc uugcacaagu     1020

cucuaacaga cguggcacug gaacaccaug aggagugcga cugcguuugu agggguucca     1080

ccgggggaug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  2956
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt3)

<400>  2956
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gacugaucuu cguguacacc cucauuugcg ccaacuuuug uagcugcagg gacacauccg      120

cuacucccca gucugcauca auaaaggccc uucggaaugc gaaccugcgc cgagaugacu      180

uguaucguag agaugagacg auccaaguca aaggaaaugg guacguucag aguccuaggu      240

ucccaaacag cuauccgcgg aauuuacugc uaaccuggcg ccuccauucc caggaaaaca      300

caaggauuca gcugguguuu gacaaucaau ucggacuuga ggaagcugag aacgauaucu      360

guagauacga cuuuguagaa guggaggaua uuucugagac uucgaccauc auacgggguc      420

gcuggugcgg ccacaaggaa gugcccccuc gaaucaaauc aagaacaaau cagauuaaga      480

ucaccuucaa aagcgacgau uauuuugucg ccaagccagg guucaagauu uacuauaguc      540

uguuggagga cuuucagccc gcagccgcuu ccgaaacuaa cugggagucu guuacaagcu      600

ccaucucagg agugaguuac aauagcccuu cugucaccga uccaacgcuc auagcagacg      660

cccuggauaa aaagauugcu gaguucgaca cuguggaaga ccugcucaaa uacuuuaacc      720

ccgaguccug gcaggaagau uuagagaaua uguaucugga caccccuagg uaccggggcc      780

guucauauca ugaucgcaag agcaaaguag accuugauag auugaacgac gaugccaaga      840

gguacaguug uacaccacgg aauuauucug uuaacauccg agaggaacug aagcuagcga      900

acguggucuu cuuuccgcgc ugccuccugg ugcaaagaug uggugggaau ugcggaugug      960

gcacugugaa cuggaggucc ugcaccugua auagcggcaa aacagucaag aaauaccacg     1020

agguucuuca guucgaaccc gggcauauua agcggcgcgg cagagcaaaa accauggccc     1080

ugguggacau ccaguuggau caccacgaga ggugcgacug caucuguucg ucucguccuc     1140

cacggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  2957
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt3)

<400>  2957
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguga       60

cccacagcaa guuccccgcc gcuggcaugu ccagaccucu ggacacaucu cucaggcuua      120

aaacuuuuuc aaguaagagc gaguaccagc uggucguuaa cgcagugcgg aaauugcaag      180

aauccggguu cuauuggucu gccguaacgg gaggugaggc gaauuuacug cuaucggcug      240

aaccagccgg caccuuucuc auccgcgauu caagcgacca gcgacauuuc uuuacacuga      300

gugugaagac ucaguccggg accaaaaacc uucguauuca gugcgaggga ggcucuuuca      360

gccugcaauc cgauccgaga ucaacacagc ccgucccuag guuugacugu guguugaagc      420

ucguucacca uuacaugcca cccccuggug caccaaguuu ccccagcccu ccaaccgaac      480

cgucuuccga ggugcccgag cagccuucag cccagccacu gcccgggagc ccuccacggc      540

gcgcuuauua cauauauagu ggaggcgaaa agaucccccu gguccucucu agaccguuau      600

ccagcaaugu ggcaacucug caacaccuuu gcaggaaaac aguaaacggc cauuuggauu      660

cguacgagaa gguuacccag cugccugggc ccauucggga auuucuagac caguaugaug      720

ccccacucug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  2958
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt3)

<400>  2958
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugc       60

ccagcgccgg ccagcuggcu cucuucgcac uugggaucgu ccuggccgcg ugccaggcuu      120

uggagaacuc caccucuccu uuaucagccg acccaccggu ugcagccgcu gugguaaguc      180

acuuuaauga uugucccgac agccauacac aauucugcuu ucacggaacu uguagauucc      240

uggugcagga agauaagccu gcaugcgucu gucauuccgg uuacgugggc gccaggugcg      300

agcacgcuga ccuacucgcc guuguggcgg caucucagaa aaagcaagcc auuacggcuc      360

uggucguggu aucgauaguu gcccuugcag ugcugaucau uaccuguguc uugauccauu      420

gcugucaggu gcggaaacac ugcgaauggu gucgcgcucu cauuugccga cacgagaagc      480

caucagcccu gcugaaaggg cguacagcgu gcugucauag cgaaacugug gucugaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  2959
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt3)

<400>  2959
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

cuagcggccu gagacuccuu ccacuguugu uaccgcugcu auggcuccug gugcuuaccc      120

ccgggaggcc ugccgcugga cuguccacau gcaagacuau cgacauggag uuggucaaac      180

ggaagcgcau ugaagcaaua cgaggucaga uccucucuaa acugcgucug gccucaccac      240

ccagucaagg cgagguuccu ccagggcccc ucccugaagc gguguuagcu cuguacaaca      300

gcacgagaga uaggguagcc ggagaguccg cagaaccaga gccggagccc gaagccgacu      360

auuacgcuaa ggaggugacc cggguccuua ugguggaaac acacaaugag auuuaugaua      420

aauucaagca gucuacucau ucgaucuaca uguuuuucaa caccucagag uugcgcgaag      480

caguuccuga gccagugcug cuaagcagag ccgaacucag gcugcuucgg cugaaguuga      540

aagucgagca gcacguggaa cucuaucaga aguacaguaa uaacuccugg cgcuaucugu      600

cuaaucgauu acuggcuccc agcgacuccc cugaguggcu cucauuugau guaacaggcg      660

uugugagaca auggcuuagu aggggugggg agauugaagg auuccggcug agcgcccauu      720

guucuugcga cucccgugau aacaccuugc aggucgacau caauggcuuu acuacaggcc      780

gcagagggga ucuagcgacc auacacggaa ugaacaggcc auuccugcuc cugauggcaa      840

cgccccuuga gcgggcccag caucugcagu caagccgaca ccgcagagcu uuggacacua      900

auuacuguuu uaguucuacc gagaaaaacu gcugugugag gcaacucuac aucgauuucc      960

ggaaggaccu ggguuggaaa uggauucacg aaccgaaggg cuaucaugcc aauuuuugcu     1020

uagggccuug ucccuacauc uggucccugg auacacagua uagcaaggug cuagcacucu     1080

acaaccagca caauccagga gcuucggccg cgccuugcug ugucccccag gcccuggaac     1140

cacuucccau uguuuauuac gugggccgca aaccuaaggu agagcaauug ucuaacauga     1200

ucgugagauc cugcaaaugu ucaugaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  2960
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt3)

<400>  2960
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugcgugcu gagcgccuuc cucauccuuc aucuggucac cguugcuuug uccuuaucua      120

cauguucaac ucuggacaug gaucaguuua ugagaaagag gauugaggca auacggggcc      180

aaauccuaag uaaacucaag cugacgagcc cucccgaaga cuauccagag ccggaagagg      240

ugcccccuga aguaauuucc aucuacaacu cuacccgcga ucuucugcag gagaaagccu      300

cgcgacgugc ggcugccugc gagagagaaa ggucagacga ggaauauuac gcaaaggagg      360

uguauaaaau ugauaugcca cccuucuuuc cuagcgagaa ugccauccca cccacauucu      420

accggccuua uuuucgcaua gucagauucg acgugagugc uauggaaaag aacgcaucca      480

auuugguuaa ggccgaguuu aggguguucc ggcuccagaa cccaaaagcu cgcgucccgg      540

aacagcgaau cgagcuguac caaauucuga agucuaaaga ucucacuagc cccacccaga      600

gauacaucga cuccaaggug guaaaaacaa gggccgaagg ggagugguua ucauuugaug      660

uuaccgacgc ggugcacgag uggcugcauc acaaggaucg gaaucuugga uucaagauua      720

guuugcauug uccuugcugu acuuuugucc caagcaacaa uuauaucaua cccaacaaau      780

cugaggaacu ggaagcacgu uucgccggua uugacggcac auccaccuac acgucagggg      840

aucagaagac uaucaaaagc acccgcaaga aaaauagugg aaagacaccu caccuacucc      900

ugaugcuucu gccaucuuau agauuggagu cccagcaaac uaacaggcgg aaaaagcgag      960

cucucgacgc cgcauacugc uuucgcaaug ugcaggacaa cuguugccug agacccuuau     1020

auauugauuu caagagggac cugggcugga aauggaucca cgaaccgaag gguuacaaug     1080

cuaacuucug ugccggggcg ugcccuuauc ucuggagcuc ggauacccag cauucucggg     1140

ugcuuucccu guacaauaca aucaaccccg aggccucagc aaguccaugu ugcgucagcc     1200

aggacuugga gccucuaacc auucuguacu auauaggaaa aacgcccaag aucgaacaac     1260

ucuccaacau gauuguuaaa ucuugcaagu guagcugagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  2961
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt3)

<400>  2961
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

ugcaucugca gagagcccuc gugguccuug cucuguugaa cuucgcaacc guuagcuuau      120

cccugucuac augcacuacg cuagacuuug gccacaucaa aaagaaaagg guggaggcca      180

uucgggggca aauacucuca aagcugcgcc uuaccagucc cccugaacca acaguaauga      240

cucacgugcc guaccagguc cuggcguugu auaauagcac ccgagagcuc cuggaagaga      300

ugcauggaga acgugaggag gguuguacac aggaaaacac cgaguccgaa uacuaugcua      360

aagagaucca caaguucgau augauucagg gccuggccga gcauaaugaa cucgcagugu      420

gccccaaggg gaucacuucu aaaguuuuua gauucaacgu gucgucaguc gagaagaaua      480

ggacaaacuu auuucgggcc gaguuccgcg ugcugagagu accuaaucca agcaguaaaa      540

ggaacgaaca acggauugaa cuuuuucaga ucuugcgccc cgacgagcac auagcuaagc      600

agcgauacau cggaggcaaa aaucugccua ccagagguac ggcagagugg cuauccuucg      660

auguuacuga caccgugagg gaauggcucc ugcggcguga gucuaaccuu gggcuggaaa      720

uuagcaucca cuguccaugc cauacauuuc agcccaaugg agauauuuug gagaacaucc      780

acgaagucau ggagauaaag uucaagggcg uggacaauga ggaugaccau ggccgcgggg      840

aucucggaag acugaaaaag caaaaagacc accacaaccc ucauuuaauu cugaugauga      900

ucccaccgca caggcucgau aaucccgguc agggcgggca gcggaagaaa cgagcccuug      960

acacuaacua uuguuuucgc aaccuggaag agaauugcug ugugagaccu uuguacauug     1020

auuucaggca ggaccuagga uggaaguggg uccaugaacc aaaaggcuau uacgcuaacu     1080

uuugcuccgg ucccuguccu uaccugcggu cagccgacac cacacacagu accguucucg     1140

ggcuguauaa uacgcuuaac ccagaggcga gcgcaucucc cugcugugug ccgcaagauc     1200

uggaaccuuu gacuauccuc uacuauguag gacgcacacc caagguggag cagcugucca     1260

auauggucgu gaagucaugc aaaugcagcu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2962
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt3)

<400>  2962
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ccguggcugu cugggcagcc cuggcgguug gccucgagcu uugggcugcc gcacacgccc      120

ugccugcuca gguggcauuc accccauacg ccccggaacc cgggagcaca ugcagauuga      180

gggaguauua cgaccaaacu gcucagaugu guugcuccaa guguucuccu ggacagcaug      240

ccaaaguauu uugcacgaag accucagaua caguguguga caguugcgaa gauagcacuu      300

auacccaguu auggaacugg gucccagagu gucuguccug cgguucucgg uguucgucag      360

accaagugga aacacaggcg ugcacccgcg agcagaaucg aaucuguacu ugccgucccg      420

gcugguacug cgcacuaagc aaacaggagg gguguagacu cugcgccccu cugaggaagu      480

gucggccagg auucggcguu gcucgccccg guacagaaac cagugaugug gucugcaaac      540

cuugugcccc agggacguuu uccaacacua ccucuagcac agacauuugc agaccgcacc      600

aaauauguaa ugugguagca auccccggaa acgcuuccau ggaugccguu ugcacuucaa      660

ccaguccuac aaggagcaug gcgccaggcg ccgugcaucu uccccagccu gucucuaccc      720

ggucccagca cacgcagcca acucccgagc cgucaacagc accuagcacc aguuuccugu      780

ugcccauggg cccaucuccu cccgcugaag gguccacugg agacuuugcc cucccagugg      840

gucugauugu gggcgucaca gcucuggggc ucuuaaucau uggaguugug aauuguguaa      900

ucaugaccca agugaagaag aaaccccugu gccuucagcg cgaggccaag gucccucauu      960

ugccagcaga uaaagcccga ggcacgcagg guccggagca acagcaucug cuaauaaccg     1020

cucccagcuc gucuuccuca agucucgaaa gcuccgcguc ugcacuggac agaagggccc     1080

cuacacggaa ccagccacag gcucccgggg uggaggccag cggagcaggc gaagcccgug     1140

cuucaacugg caguuccgau agcucuccug ggggacacgg uacccaaguu aaugugacau     1200

guaucgucaa cgugugcuca aguagcgacc acuccucuca gugcucgagc caggccuccu     1260

caacuauggg cgauaccgac aguucuccaa gcgagucccc caaggacgaa cagguaccgu     1320

ucucaaaaga ggagugugca uuucgcagcc aacuugaaac accugagacc cuguuggggu     1380

cuacugaaga gaagccacuc ccccugggag uuccugaugc gggcaugaag cccuccugag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  2963
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt3)

<400>  2963
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

ugaugagacu guucccuugc uuucuccagc uucuggccgg cuuggcuuua ccagcagucc      120

cgccccaaca gugggcccug agcgcgggga acggauccuc ugagguugaa gugguaccuu      180

uccaggaggu gugggguagg ucauacuguc gggcucuaga acgccucguc gacgugguua      240

gugaguaucc aagcgaagug gagcacaugu uuucccccuc uugcgucucg cugcuucgau      300

guaccggcug cuguggggau gagaaucugc auugcgugcc uguagaaaca gccaacguua      360

cuaugcaguu gcucaagauc cguucaggag acagaccaag cuacguggag cugacguuca      420

gucaacacgu caggugugaa ugccggcccc ugcgcgagaa aaugaagccu gagagaaggc      480

ggccaaaagg ccgcgguaag cgaagaaggg aaaaacagcg gccgaccgau ugucaucucu      540

gcggggacgc agugccccgu cgcugaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  2964
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt3)

<400>  2964
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

acagacagac agauacugcc cccagcccuu ccuaccaucu gcucccaggc aggcggcgca      120

cgguggacgc ugcagccucu cgagggcaag gaccggagcc cgcgccuggu ggcggggucg      180

aaggaguugg cgcucguggu guggcccuua agcuguucgu acaguuguua gggugcucaa      240

gauuuggagg cgcagugguc agggccggcg aggcugaacc aaguggggca gcccggagcg      300

cuuccucugg acgcgaggaa ccccagccug aggaggguga agaggaagag gagaaagaag      360

aggaaagagg cccacagugg aggcuggggg cccggaagcc cggaucgugg accggcgagg      420

cggcagugug ugccgauuca gcuccugccg cacgcgcucc acaagcccua gcgcgagcca      480

gcgguagagg gggaaggguu gcacggcgug gcgcugaaga gaguggcccg ccccacuccc      540

cuucucgcag agggagcgcc uccagggcug gaccaggucg ggccucagag acaaugaacu      600

uccuccugag uugggugcac uggagccuug cacuguugcu cuaucugcau cacgccaaau      660

ggucucaggc ugcgcccaug gcagaaggcg ggggacagaa ucaucacgag gucgugaagu      720

uuauggacgu auaccagcga uccuauugcc acccuaucga aacucugguu gauauuuucc      780

aagaguaccc agacgaaaua gaguauaucu uuaaacccuc augugugccg cucaugcgcu      840

gcggcgguug uugcaacgau gagggguuag aauguguccc uaccgaggaa agcaauauua      900

caaugcagau caugagaauu aagccccauc agggccagca caucggagag augaguuucc      960

ugcaacauaa caagugcgaa uguaggccua aaaaggaccg ggcccgccag gagaaaaagu     1020

cugugagagg caaagggaag ggacagaaga ggaaacguaa gaaaucccgg uacaagagcu     1080

ggucggugua ugucggugcu cgaugcuguc uuaugccaug gucuuugccc ggcccacacc     1140

ccugcgggcc uugcuccgag agaaggaaac accuguuugu ucaagaucca cagaccugua     1200

agugcucaug uaaaaauacu gacagucgcu gcaaggcccg gcagcuagaa cucaacgaga     1260

gaacauguag gugcgauaag ccgcgccgau gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  2965
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt3)

<400>  2965
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugcucag cugggugcac uggucccuug cccuguuguu auaccugcau cacgcuaagu      120

ggucucaggc agcccccaug gcggagggcg ggggacaaaa ucaucacgaa gucguuaaau      180

uuauggacgu guaucagaga ucauacugcc auccuaucga gacccuagua gauauuuucc      240

aggaauaucc agacgagaua gaauacaucu uuaagccgag uugugugccc cucaugaggu      300

gcgguggcug uugcaacgau gaggggcugg aguguguccc uacagaagag agcaauauua      360

cuaugcagau caugcggauu aaaccacacc aaggacagca caucggcgaa auguccuucc      420

uucagcauaa caagugcgag ugucgcccca aaaaggaccg agcucgucag gagaagaaau      480

cugugagagg uaaggggaaa ggacaaaaga ggaaacggaa gaagucgcgc uauaaaucau      540

ggagcguuua cgugggcgcc agaugcuguc ugaugccuug gaguuugcca ggcccccacc      600

cuugcgggcc auguuccgaa aggcggaagc aucucuuugu ccaggauccg cagacgugca      660

aaugcucuug uaagaauacc gacagccgcu gcaaagcacg acagcuggag cugaacgaaa      720

gaacauguag gugcgauaag ccccggcguu gaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  2966
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt3)

<400>  2966
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

cccugcucag aaggcuucug uuggccgcuu uacugcagcu agccccugca caagcgccag      120

ugucccagcc ggacgcuccc ggccaccagc ggaaggucgu uucuuggauc gauguguaca      180

cccgcgccac augccagccu cgagagguag uggucccacu cacuguggaa cugaugggga      240

cgguugcaaa acaacuugug cccucaugug ucaccgugca gcguugcgga gguuguugcc      300

cugacgaugg ccuggagugu guaccaacag ggcagcauca gguuagaaug caaauuuuga      360

ugauaaggua ucccaguagc cagcucggag aaaugucccu ggaggaacac ucucagugcg      420

agugucggcc uaagaaaaag gacucggccg ugaaaccaga ucgcgcugca acuccgcauc      480

acagacccca gccuagguca gucccaggcu gggacagcgc ccccggugcu ccuaguccag      540

ccgauaucac ccaucccaca ccggcgccug ggcccuccgc acacgccgcu ccaucuacca      600

cuagcgcccu gacaccugga cccgcagcug ccgcggccga cgcagcugcc uccucagugg      660

cuaagggcgg cgccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  2967
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt3)

<400>  2967
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

uucucggcuu cuuuagcgug gccugcuccc uucuggcugc agccuuguua cccgggccua      120

gagaggcgcc agcugccgca gccgcuuucg aaucuggacu ggaccuauca gaugcagagc      180

cggacgccgg ugaagcuacc gccuacgcga guaaggaucu cgaggaacag cugaggagcg      240

ucuccucugu ugacgagcuu augacagugc uguaucccga guacuggaaa auguauaagu      300

gucaauugcg gaaaggcggg uggcagcaua accgcgaaca ggcaaaucuc aacucgcgaa      360

cugaggaaac gaucaaguuu gccgcugccc acuacaauac cgagauucug aaaucaauag      420

auaacgagug gcguaagaca cagugcaugc cuagagaagu auguaucgac gugggaaagg      480

aguucggcgu cgcaacuaau accuuuuuca aaccacccug cgugagcguu uauaggugug      540

gugggugcug uaacagugaa ggacugcaau gcaugaauac auccaccucu uaccucagca      600

agacuuuauu ugagauuaca gugccucugu cccagggccc aaaacccguc accaucucau      660

ucgcuaacca uacgaguugu cggugcauga gcaagcugga uguguaucgc cagguacacu      720

cuauuaucag aagguccuug ccugccacuc ugccacagug ucaagcggcc aauaaaaccu      780

gcccgacaaa cuacaugugg aauaaccaua uaugccggug ucuagcacag gaagacuuua      840

uguucucaag cgaugcuggc gacgauagua cugacggguu ucacgauauc ugcggaccca      900

auaaggagcu cgacgaggaa accugucagu gcguuugucg cgccggucug cgaccugcuu      960

cuugcggccc acacaaggag cuugacagaa acuccuguca gugcgugugu aaaaauaagc     1020

uguuccccag ccaaugcggg gccaacaggg aauuugauga gaacacaugu cagugcgucu     1080

gcaaacggac cuguccucgu aaucagccau ugaaccccgg aaagugcgca ugugaaugca     1140

cggagucgcc gcaaaaaugu cuccugaagg gcaaaaaguu ccaucaccag acuugcucuu     1200

guuaccgcag accuugcaca aauaggcaga aggccuguga gcccgguuuc uccuauucag     1260

aagaggugug ccggugugug ccaaguuacu ggaaacgacc ucagaugagc ugaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  2968
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt3)

<400>  2968
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguaca       60

gagagugggu ggucguuaac guguucauga ugcuguaugu acagcucgug caaggcagcu      120

ccaaugaaca cgggcccguc aagaggucuu cacagaguac ccuugagcgg agcgaacagc      180

agauccgcgc cgcuuccucu cuggaggaau uguuacgaau uacacauucg gaggacugga      240

aacuguggcg uugcagacua aggcucaagu cauuuacuag cauggauagu cgguccgcau      300

cucaccgcag cacgagauuc gccgcgaccu uuuacgacau agagacacug aaagugaucg      360

augaagagug gcaaaggacu caguguuccc cucgggaaac cugcguugag guggcuucag      420

agcuuggaaa gaguacaaac accuucuuua aaccaccgug ugucaaugug uuccgcugcg      480

guggcuguug caacgaagag agccugauuu guaugaauac uucuacaucc uauaucucaa      540

agcaguuguu ugaaauuagc guaccccuca ccaguguucc ugagcuggug ccagucaagg      600

uggccaacca uacggggugc aaaugucugc ccacugcacc ucgacaccca uacucuauca      660

uaagaagguc cauccagauu cccgaagagg accggugcag ccauucgaag aaacucuguc      720

cuaucgauau guuaugggac ucuaauaagu gcaaaugcgu gcugcaagag gaaaacccac      780

uugccggaac cgaggaucac ucccacuugc aggaaccggc ucuguguggc ccccauauga      840

uguucgacga ggaucguugc gaaugugucu gcaagacacc uuguccaaag gaccuaauuc      900

agcaccccaa aaauugcuca uguuuugagu gcaaggagag ucucgaaacu uguugccaga      960

aacauaagcu guuccacccu gauaccugua gcugcgagga ccgcugccca uuucacacaa     1020

gacccugugc auccgguaaa accgccugcg cuaagcauug uagguucccg aaagaaaagc     1080

gggccgcgca agggccucac ucucgaaaga accccugagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  2969
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt4)

<400>  2969
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcgacgagac cggcuucgag cacagcggcc ugugggugag cgugcuggcc ggccugcugc      120

ugggcgccug ccaggcccac cccauccccg acagcagccc ccugcugcag uucggcggcc      180

aggugagaca gagauaccug uacaccgacg acgcccagca gaccgaggcc caccuggaga      240

ucagagagga cggcaccgug ggcggcgccg ccgaccagag ccccgagagc cugcugcagc      300

ugaaggcccu gaagcccggc gugauccaga uccugggcgu gaagaccagc agauuccugu      360

gccagagacc cgacggcgcc cuguacggca gccugcacuu cgaccccgag gccugcagcu      420

ucagagagcu gcugcuggag gacggcuaca acguguacca gagcgaggcc cacggccugc      480

cccugcaccu gcccggcaac aagagccccc acagagaccc cgcccccaga ggccccgcca      540

gauuccugcc ccugcccggc cugccccccg cccugcccga gccccccggc auccuggccc      600

cccagccccc cgacgugggc agcagcgacc cccugagcau ggugggcccc agccagggca      660

gaagccccag cuacgccagc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  2970
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt4)

<400>  2970
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuucccccc ccugcugcug cugcuguucu ggggcguggu gagccacagc uuccccgcca      120

cccuggagac ccaggagcag gacguggacc uggugcagaa guaccuggag aaguacuaca      180

accugaagaa cgacggcaga cagguggaga agagaagaaa cagcggcccc gugguggaga      240

agcugaagca gaugcaggag uucuucggcc ugaaggugac cggcaagccc gacgccgaga      300

cccugaaggu gaugaagcag cccagaugcg gcgugcccga cguggcccag uucgugcuga      360

ccgagggcaa ccccagaugg gagcagaccc accugaccua cagaaucgag aacuacaccc      420

ccgaccugcc cagagccgac guggaccacg ccaucgagaa ggccuuccag cuguggagca      480

acgugacccc ccugaccuuc accaagguga gcgagggcca ggccgacauc augaucagcu      540

ucgugagagg cgaccacaga gacaacagcc ccuucgacgg ccccggcggc aaccuggccc      600

acgccuucca gcccggcccc ggcaucggcg gcgacgccca cuucgacgag gacgagagau      660

ggaccaacaa cuucagagag uacaaccugc acagaguggc cgcccacgag cugggccaca      720

gccugggccu gagccacagc accgacaucg gcgcccugau guaccccagc uacaccuuca      780

gcggcgacgu gcagcuggcc caggacgaca ucgacggcau ccaggccauc uacggcagaa      840

gccagaaccc cgugcagccc aucggccccc agacccccaa ggccugcgac agcaagcuga      900

ccuucgacgc caucaccacc aucagaggcg aggugauguu cuucaaggac agauucuaca      960

ugagaaccaa ccccuucuac cccgaggugg agcugaacuu caucagcgug uucuggcccc     1020

agcugcccaa cggccuggag gccgccuacg aguucgccga cagagacgag gugagauucu     1080

ucaagggcaa caaguacugg gccgugcagg gccagaacgu gcugcacggc uaccccaagg     1140

acaucuacag cagcuucggc uuccccagaa ccgugaagca caucgacgcc gcccugagcg     1200

aggagaacac cggcaagacc uacuucuucg uggccaacaa guacuggaga uacgacgagu     1260

acaagagaag cauggacccc ggcuacccca agaugaucgc ccacgacuuc cccggcaucg     1320

gccacaaggu ggacgccgug uucaugaagg acggcuucuu cuacuucuuc cacggcacca     1380

gacaguacaa guucgacccc aagaccaaga gaauccugac ccugcagaag gccaacagcu     1440

gguucaacug cagaaagaac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  2971
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt4)

<400>  2971
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuucccccc ccugcugcug cugcuguucu ggggcguggu gagccacagc uucgugcuga      120

ccgagggcaa ccccagaugg gagcagaccc accugaccua cagaaucgag aacuacaccc      180

ccgaccugcc cagagccgac guggaccacg ccaucgagaa ggccuuccag cuguggagca      240

acgugacccc ccugaccuuc accaagguga gcgagggcca ggccgacauc augaucagcu      300

ucgugagagg cgaccacaga gacaacagcc ccuucgacgg ccccggcggc aaccuggccc      360

acgccuucca gcccggcccc ggcaucggcg gcgacgccca cuucgacgag gacgagagau      420

ggaccaacaa cuucagagag uacaaccugc acagaguggc cgcccacgag cugggccaca      480

gccugggccu gagccacagc accgacaucg gcgcccugau guaccccagc uacaccuuca      540

gcggcgacgu gcagcuggcc caggacgaca ucgacggcau ccaggccauc uacggcagaa      600

gccagaaccc cgugcagccc aucggccccc agacccccaa ggccugcgac agcaagcuga      660

ccuucgacgc caucaccacc aucagaggcg aggugauguu cuucaaggac agauucuaca      720

ugagaaccaa ccccuucuac cccgaggugg agcugaacuu caucagcgug uucuggcccc      780

agcugcccaa cggccuggag gccgccuacg aguucgccga cagagacgag gugagauucu      840

ucaagggcaa caaguacugg gccgugcagg gccagaacgu gcugcacggc uaccccaagg      900

acaucuacag cagcuucggc uuccccagaa ccgugaagca caucgacgcc gcccugagcg      960

aggagaacac cggcaagacc uacuucuucg uggccaacaa guacuggaga uacgacgagu     1020

acaagagaag cauggacccc ggcuacccca agaugaucgc ccacgacuuc cccggcaucg     1080

gccacaaggu ggacgccgug uucaugaagg acggcuucuu cuacuucuuc cacggcacca     1140

gacaguacaa guucgacccc aagaccaaga gaauccugac ccugcagaag gccaacagcu     1200

gguucaacug cagaaagaac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  2972
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt4)

<400>  2972
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

agaacauccu gaagauccug auggacagcu acagcaagga gagcaagauc cagaccguga      120

gaagagugac cagcgugagc cugcuggccg uguaccugac caugaacacc agcagccugg      180

ugcuggccaa gcccaucgag aacaccaacg acaccagcau caagaacgug gagaagcuga      240

gaaacgcccc caacgaggag aacagcaaga agguggagga cagcaagaac gacaaggugg      300

agcacgugaa gaacaucgag gaggccaagg uggagcaggu ggcccccgag gugaagagca      360

agagcacccu gagaagcgcc agcaucgcca acaccaacag cgagaaguac gacuucgagu      420

accugaacgg ccugagcuac accgagcuga ccaaccugau caagaacauc aaguggaacc      480

agaucaacgg ccuguucaac uacagcaccg gcagccagaa guucuucggc gacaagaaca      540

gagugcaggc caucaucaac gcccugcagg agagcggcag aaccuacacc gccaacgaca      600

ugaagggcau cgagaccuuc accgaggugc ugagagccgg cuucuaccug ggcuacuaca      660

acgacggccu gagcuaccug aacgacagaa acuuccagga caagugcauc cccgccauga      720

ucgccaucca gaagaacccc aacuucaagc ugggcaccgc cgugcaggac gaggugauca      780

ccagccuggg caagcugauc ggcaacgcca gcgccaacgc cgagguggug aacaacugcg      840

ugcccgugcu gaagcaguuc agagagaacc ugaaccagua cgcccccgac uacgugaagg      900

gcaccgccgu gaacgagcug aucaagggca ucgaguucga cuucagcggc gccgccuacg      960

agaaggacgu gaagaccaug cccugguacg gcaagaucga ccccuucauc aacgagcuga     1020

aggcccuggg ccuguacggc aacaucacca gcgccaccga gugggccagc gacgugggca     1080

ucuacuaccu gagcaaguuc ggccuguaca gcaccaacag aaacgacauc gugcagagcc     1140

uggagaaggc cguggacaug uacaaguacg gcaagaucgc cuucguggcc auggagagaa     1200

ucaccuggga cuacgacggc aucggcagca acggcaagaa gguggaccac gacaaguucc     1260

uggacgacgc cgagaagcac uaccugccca agaccuacac cuucgacaac ggcaccuuca     1320

ucaucagagc cggcgacaag gugagcgagg agaagaucaa gagacuguac ugggccagca     1380

gagaggugaa gagccaguuc cacagagugg ugggcaacga caaggcccug gaggugggca     1440

acgccgacga cgugcugacc augaagaucu ucaacagccc cgaggaguac aaguucaaca     1500

ccaacaucaa cggcgugagc accgacaacg gcggccugua caucgagccc agaggcaccu     1560

ucuacaccua cgagagaacc ccccagcaga gcaucuucag ccuggaggag cuguucagac     1620

acgaguacac ccacuaccug caggccagau accuggugga cggccugugg ggccagggcc     1680

ccuucuacga gaagaacaga cugaccuggu ucgacgaggg caccgccgag uucuucgccg     1740

gcagcaccag aaccagcggc gugcugccca gaaagagcau ccugggcuac cuggccaagg     1800

acaaggugga ccacagauac agccugaaga agacccugaa cagcggcuac gacgacagcg     1860

acuggauguu cuacaacuac ggcuucgccg uggcccacua ccuguacgag aaggacaugc     1920

ccaccuucau caagaugaac aaggccaucc ugaacaccga cgugaagagc uacgacgaga     1980

ucaucaagaa gcugagcgac gacgccaaca agaacaccga guaccagaac cacauccagg     2040

agcuggccga caaguaccag ggcgccggca ucccccuggu gagcgacgac uaccugaagg     2100

accacggcua caagaaggcc agcgaggugu acagcgagau cagcaaggcc gccagccuga     2160

ccaacaccag cgugaccgcc gagaagagcc aguacuucaa caccuucacc cugagaggca     2220

ccuacaccgg cgagaccagc aagggcgagu ucaaggacug ggacgagaug agcaagaagc     2280

uggacggcac ccuggagagc cuggccaaga acagcuggag cggcuacaag acccugaccg     2340

ccuacuucac caacuacaga gugaccagcg acaacaaggu gcaguacgac gugguguucc     2400

acggcgugcu gaccgacaac gccgacauca gcaacaacaa ggcccccauc gccaagguga     2460

ccggccccag caccggcgcc gugggcagaa acaucgaguu cagcggcaag gacagcaagg     2520

acgaggacgg caagaucgug agcuacgacu gggacuucgg cgacggcgcc accagcagag     2580

gcaagaacag cgugcacgcc uacaagaagg ccggcaccua caacgugacc cugaagguga     2640

ccgacgacaa gggcgccacc gccaccgaga gcuucaccau cgagaucaag aacgaggaca     2700

ccaccacccc caucaccaag gagauggagc ccaacgacga caucaaggag gccaacggcc     2760

ccaucgugga gggcgugacc gugaagggcg accugaacgg cagcgacgac gccgacaccu     2820

ucuacuucga cgugaaggag gacggcgacg ugaccaucga gcugcccuac agcggcagca     2880

gcaacuucac cuggcuggug uacaaggagg gcgacgacca gaaccacauc gccagcggca     2940

ucgacaagaa caacagcaag gugggcaccu ucaagagcac caagggcaga cacuacgugu     3000

ucaucuacaa gcacgacagc gccagcaaca ucagcuacag ccugaacauc aagggccugg     3060

gcaacgagaa gcugaaggag aaggagaaca acgacagcag cgacaaggcc accgugaucc     3120

ccaacuucaa caccaccaug cagggcagcc ugcugggcga cgacagcaga gacuacuaca     3180

gcuucgaggu gaaggaggag ggcgagguga acaucgagcu ggacaagaag gacgaguucg     3240

gcgugaccug gacccugcac cccgagagca acaucaacga cagaaucacc uacggccagg     3300

uggacggcaa caaggugagc aacaagguga agcugagacc cggcaaguac uaccugcugg     3360

uguacaagua cagcggcagc ggcaacuacg agcugagagu gaacaaguga ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  2973
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt4)

<400>  2973
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cuguuccugu ucagcagcgc cuacagcauc gccaacacca      120

acagcgagaa guacgacuuc gaguaccuga acggccugag cuacaccgag cugaccaacc      180

ugaucaagaa caucaagugg aaccagauca acggccuguu caacuacagc accggcagcc      240

agaaguucuu cggcgacaag aacagagugc aggccaucau caacgcccug caggagagcg      300

gcagaaccua caccgccaac gacaugaagg gcaucgagac cuucaccgag gugcugagag      360

ccggcuucua ccugggcuac uacaacgacg gccugagcua ccugaacgac agaaacuucc      420

aggacaagug cauccccgcc augaucgcca uccagaagaa ccccaacuuc aagcugggca      480

ccgccgugca ggacgaggug aucaccagcc ugggcaagcu gaucggcaac gccagcgcca      540

acgccgaggu ggugaacaac ugcgugcccg ugcugaagca guucagagag aaccugaacc      600

aguacgcccc cgacuacgug aagggcaccg ccgugaacga gcugaucaag ggcaucgagu      660

ucgacuucag cggcgccgcc uacgagaagg acgugaagac caugcccugg uacggcaaga      720

ucgaccccuu caucaacgag cugaaggccc ugggccugua cggcaacauc accagcgcca      780

ccgagugggc cagcgacgug ggcaucuacu accugagcaa guucggccug uacagcacca      840

acagaaacga caucgugcag agccuggaga aggccgugga cauguacaag uacggcaaga      900

ucgccuucgu ggccauggag agaaucaccu gggacuacga cggcaucggc agcaacggca      960

agaaggugga ccacgacaag uuccuggacg acgccgagaa gcacuaccug cccaagaccu     1020

acaccuucga caacggcacc uucaucauca gagccggcga caaggugagc gaggagaaga     1080

ucaagagacu guacugggcc agcagagagg ugaagagcca guuccacaga guggugggca     1140

acgacaaggc ccuggaggug ggcaacgccg acgacgugcu gaccaugaag aucuucaaca     1200

gccccgagga guacaaguuc aacaccaaca ucaacggcgu gagcaccgac aacggcggcc     1260

uguacaucga gcccagaggc accuucuaca ccuacgagag aaccccccag cagagcaucu     1320

ucagccugga ggagcuguuc agacacgagu acacccacua ccugcaggcc agauaccugg     1380

uggacggccu guggggccag ggccccuucu acgagaagaa cagacugacc ugguucgacg     1440

agggcaccgc cgaguucuuc gccggcagca ccagaaccag cggcgugcug cccagaaaga     1500

gcauccuggg cuaccuggcc aaggacaagg uggaccacag auacagccug aagaagaccc     1560

ugaacagcgg cuacgacgac agcgacugga uguucuacaa cuacggcuuc gccguggccc     1620

acuaccugua cgagaaggac augcccaccu ucaucaagau gaacaaggcc auccugaaca     1680

ccgacgugaa gagcuacgac gagaucauca agaagcugag cgacgacgcc aacaagaaca     1740

ccgaguacca gaaccacauc caggagcugg ccgacaagua ccagggcgcc ggcauccccc     1800

uggugagcga cgacuaccug aaggaccacg gcuacaagaa ggccagcgag guguacagcg     1860

agaucagcaa ggccgccagc cugaccaaca ccagcgugac cgccgagaag agccaguacu     1920

ucaacaccuu cacccugaga ggcaccuaca ccggcgagac cagcaagggc gaguucaagg     1980

acugggacga gaugagcaag aagcuggacg gcacccugga gagccuggcc aagaacagcu     2040

ggagcggcua caagacccug accgccuacu ucaccaacua cagagugacc agcgacaaca     2100

aggugcagua cgacguggug uuccacggcg ugcugaccga caacgccgac aucagcaaca     2160

acaaggcccc caucgccaag gugaccggcc ccagcaccgg cgccgugggc agaaacaucg     2220

aguucagcgg caaggacagc aaggacgagg acggcaagau cgugagcuac gacugggacu     2280

ucggcgacgg cgccaccagc agaggcaaga acagcgugca cgccuacaag aaggccggca     2340

ccuacaacgu gacccugaag gugaccgacg acaagggcgc caccgccacc gagagcuuca     2400

ccaucgagau caagaacgag gacaccacca cccccaucac caaggagaug gagcccaacg     2460

acgacaucaa ggaggccaac ggccccaucg uggagggcgu gaccgugaag ggcgaccuga     2520

acggcagcga cgacgccgac accuucuacu ucgacgugaa ggaggacggc gacgugacca     2580

ucgagcugcc cuacagcggc agcagcaacu ucaccuggcu gguguacaag gagggcgacg     2640

accagaacca caucgccagc ggcaucgaca agaacaacag caaggugggc accuucaaga     2700

gcaccaaggg cagacacuac guguucaucu acaagcacga cagcgccagc aacaucagcu     2760

acagccugaa caucaagggc cugggcaacg agaagcugaa ggagaaggag aacaacgaca     2820

gcagcgacaa ggccaccgug auccccaacu ucaacaccac caugcagggc agccugcugg     2880

gcgacgacag cagagacuac uacagcuucg aggugaagga ggagggcgag gugaacaucg     2940

agcuggacaa gaaggacgag uucggcguga ccuggacccu gcaccccgag agcaacauca     3000

acgacagaau caccuacggc cagguggacg gcaacaaggu gagcaacaag gugaagcuga     3060

gacccggcaa guacuaccug cugguguaca aguacagcgg cagcggcaac uacgagcuga     3120

gagugaacaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  2974
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt4)

<400>  2974
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cuguuccugu ucagcagcgc cuacagcaug aagaagaaca      120

uccugaagau ccugauggac agcuacagca aggagagcaa gauccagacc gugagaagag      180

ugaccagcgu gagccugcug gccguguacc ugaccaugaa caccagcagc cuggugcugg      240

ccaagcccau cgagaacacc aacgacacca gcaucaagaa cguggagaag cugagaaacg      300

cccccaacga ggagaacagc aagaaggugg aggacagcaa gaacgacaag guggagcacg      360

ugaagaacau cgaggaggcc aagguggagc agguggcccc cgaggugaag agcaagagca      420

cccugagaag cgccagcaga agaagaagaa agagaaucgc caacaccaac agcgagaagu      480

acgacuucga guaccugaac ggccugagcu acaccgagcu gaccaaccug aucaagaaca      540

ucaaguggaa ccagaucaac ggccuguuca acuacagcac cggcagccag aaguucuucg      600

gcgacaagaa cagagugcag gccaucauca acgcccugca ggagagcggc agaaccuaca      660

ccgccaacga caugaagggc aucgagaccu ucaccgaggu gcugagagcc ggcuucuacc      720

ugggcuacua caacgacggc cugagcuacc ugaacgacag aaacuuccag gacaagugca      780

uccccgccau gaucgccauc cagaagaacc ccaacuucaa gcugggcacc gccgugcagg      840

acgaggugau caccagccug ggcaagcuga ucggcaacgc cagcgccaac gccgaggugg      900

ugaacaacug cgugcccgug cugaagcagu ucagagagaa ccugaaccag uacgcccccg      960

acuacgugaa gggcaccgcc gugaacgagc ugaucaaggg caucgaguuc gacuucagcg     1020

gcgccgccua cgagaaggac gugaagacca ugcccuggua cggcaagauc gaccccuuca     1080

ucaacgagcu gaaggcccug ggccuguacg gcaacaucac cagcgccacc gagugggcca     1140

gcgacguggg caucuacuac cugagcaagu ucggccugua cagcaccaac agaaacgaca     1200

ucgugcagag ccuggagaag gccguggaca uguacaagua cggcaagauc gccuucgugg     1260

ccauggagag aaucaccugg gacuacgacg gcaucggcag caacggcaag aagguggacc     1320

acgacaaguu ccuggacgac gccgagaagc acuaccugcc caagaccuac accuucgaca     1380

acggcaccuu caucaucaga gccggcgaca aggugagcga ggagaagauc aagagacugu     1440

acugggccag cagagaggug aagagccagu uccacagagu ggugggcaac gacaaggccc     1500

uggagguggg caacgccgac gacgugcuga ccaugaagau cuucaacagc cccgaggagu     1560

acaaguucaa caccaacauc aacggcguga gcaccgacaa cggcggccug uacaucgagc     1620

ccagaggcac cuucuacacc uacgagagaa ccccccagca gagcaucuuc agccuggagg     1680

agcuguucag acacgaguac acccacuacc ugcaggccag auaccuggug gacggccugu     1740

ggggccaggg ccccuucuac gagaagaaca gacugaccug guucgacgag ggcaccgccg     1800

aguucuucgc cggcagcacc agaaccagcg gcgugcugcc cagaaagagc auccugggcu     1860

accuggccaa ggacaaggug gaccacagau acagccugaa gaagacccug aacagcggcu     1920

acgacgacag cgacuggaug uucuacaacu acggcuucgc cguggcccac uaccuguacg     1980

agaaggacau gcccaccuuc aucaagauga acaaggccau ccugaacacc gacgugaaga     2040

gcuacgacga gaucaucaag aagcugagcg acgacgccaa caagaacacc gaguaccaga     2100

accacaucca ggagcuggcc gacaaguacc agggcgccgg caucccccug gugagcgacg     2160

acuaccugaa ggaccacggc uacaagaagg ccagcgaggu guacagcgag aucagcaagg     2220

ccgccagccu gaccaacacc agcgugaccg ccgagaagag ccaguacuuc aacaccuuca     2280

cccugagagg caccuacacc ggcgagacca gcaagggcga guucaaggac ugggacgaga     2340

ugagcaagaa gcuggacggc acccuggaga gccuggccaa gaacagcugg agcggcuaca     2400

agacccugac cgccuacuuc accaacuaca gagugaccag cgacaacaag gugcaguacg     2460

acgugguguu ccacggcgug cugaccgaca acgccgacau cagcaacaac aaggccccca     2520

ucgccaaggu gaccggcccc agcaccggcg ccgugggcag aaacaucgag uucagcggca     2580

aggacagcaa ggacgaggac ggcaagaucg ugagcuacga cugggacuuc ggcgacggcg     2640

ccaccagcag aggcaagaac agcgugcacg ccuacaagaa ggccggcacc uacaacguga     2700

cccugaaggu gaccgacgac aagggcgcca ccgccaccga gagcuucacc aucgagauca     2760

agaacgagga caccaccacc cccaucacca aggagaugga gcccaacgac gacaucaagg     2820

aggccaacgg ccccaucgug gagggcguga ccgugaaggg cgaccugaac ggcagcgacg     2880

acgccgacac cuucuacuuc gacgugaagg aggacggcga cgugaccauc gagcugcccu     2940

acagcggcag cagcaacuuc accuggcugg uguacaagga gggcgacgac cagaaccaca     3000

ucgccagcgg caucgacaag aacaacagca aggugggcac cuucaagagc accaagggca     3060

gacacuacgu guucaucuac aagcacgaca gcgccagcaa caucagcuac agccugaaca     3120

ucaagggccu gggcaacgag aagcugaagg agaaggagaa caacgacagc agcgacaagg     3180

ccaccgugau ccccaacuuc aacaccacca ugcagggcag ccugcugggc gacgacagca     3240

gagacuacua cagcuucgag gugaaggagg agggcgaggu gaacaucgag cuggacaaga     3300

aggacgaguu cggcgugacc uggacccugc accccgagag caacaucaac gacagaauca     3360

ccuacggcca gguggacggc aacaagguga gcaacaaggu gaagcugaga cccggcaagu     3420

acuaccugcu gguguacaag uacagcggca gcggcaacua cgagcugaga gugaacaagu     3480

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  2975
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt4)

<400>  2975
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugaagau cauccugaac agaggcaaga ccaugaagag aaagugccug agcaagagac      120

ugaugcuggc caucaccaug gccaccaucu ucaccgugaa cagcacccug cccaucuacg      180

ccgccgugga caagaacaac gccaccgccg ccgugcagaa cgagagcaag agauacaccg      240

ugagcuaccu gaagacccug aacuacuacg accuggugga ccugcuggug aagaccgaga      300

ucgagaaccu gcccgaccug uuccaguaca gcagcgacgc caaggaguuc uacggcaaca      360

agaccagaau gagcuucauc auggacgaga ucggcagaag agccccccag uacaccgaga      420

ucgaccacaa gggcaucccc acccuggugg agguggugag agccggcuuc uaccugggcu      480

uccacaacaa ggagcugaac gagaucaaca agagaagcuu caaggagaga gugaucccca      540

gcauccuggc cauccagaag aaccccaacu ucaagcuggg caccgaggug caggacaaga      600

ucgugagcgc caccggccug cuggccggca acgagaccgc cccccccgag guggugaaca      660

acuucacccc cauccugcag gacugcauca agaacaucga cagauacgcc cuggacgacc      720

ugaagagcaa ggcccuguuc aacgugcugg ccgcccccac cuacgacauc accgaguacc      780

ugagagccac caaggagaag cccgagaaca cccccuggua cggcaagauc gacggcuuca      840

ucaacgagcu gaagaagcug gcccuguacg gcaagaucaa cgacaacaac agcuggauca      900

ucgacaacgg caucuaccac aucgcccccc ugggcaagcu gcacagcaac aacaagaucg      960

gcaucgagac ccugaccgag gugaugaagg uguaccccua ccugagcaug cagcaccugc     1020

agagcgccga ccagaucaag agacacuacg acagcaagga cgccgagggc aacaagaucc     1080

cccuggacaa guucaagaag gagggcaagg agaaguacug ccccaagacc uacaccuucg     1140

acgacggcaa ggugaucauc aaggccggcg ccagagugga ggaggagaag gugaagagac     1200

uguacugggc cagcaaggag gugaacagcc aguucuucag aguguacggc aucgacaagc     1260

cccuggagga gggcaacccc gacgacaucc ugaccauggu gaucuacaac agccccgagg     1320

aguacaagcu gaacagcgug cuguacggcu acgacaccaa caacggcggc auguacaucg     1380

agcccgaggg caccuucuuc accuacgaga gagaggccca ggagagcacc uacacccugg     1440

aggagcuguu cagacacgag uacacccacu accugcaggg cagauacgcc gugcccggcc     1500

aguggggcag aaccaagcug uacgacaacg acagacugac cugguacgag gagggcggcg     1560

ccgagcuguu cgccggcagc accagaacca gcggcauccu gcccagaaag agcaucguga     1620

gcaacaucca caacaccacc agaaacaaca gauacaagcu gagcgacacc gugcacagca     1680

aguacggcgc cagcuucgag uucuacaacu acgccugcau guucauggac uacauguaca     1740

acaaggacau gggcauccug aacaagcuga acgaccuggc caagaacaac gacguggacg     1800

gcuacgacaa cuacaucaga gaccugagca gcaacuacgc ccugaacgac aaguaccagg     1860

accacaugca ggagagaauc gacaacuacg agaaccugac cgugcccuuc guggccgacg     1920

acuaccuggu gagacacgcc uacaagaacc ccaacgagau cuacagcgag aucagcgagg     1980

uggccaagcu gaaggacgcc aagagcgagg ugaagaagag ccaguacuuc agcaccuuca     2040

cccugagagg cagcuacacc ggcggcgcca gcaagggcaa gcuggaggac cagaaggcca     2100

ugaacaaguu caucgacgac agccugaaga agcuggacac cuacagcugg agcggcuaca     2160

agacccugac cgccuacuuc accaacuaca agguggacag cagcaacaga gugaccuacg     2220

acgugguguu ccacggcuac cugcccaacg agggcgacag caagaacagc cugcccuacg     2280

gcaagaucaa cggcaccuac aagggcaccg agaaggagaa gaucaaguuc agcagcgagg     2340

gcagcuucga ccccgacggc aagaucguga gcuacgagug ggacuucggc gacggcaaca     2400

agagcaacga ggagaacccc gagcacagcu acgacaaggu gggcaccuac accgugaagc     2460

ugaaggugac cgacgacaag ggcgagagca gcgugagcac caccaccgcc gagaucaagg     2520

accugagcga gaacaagcug cccgugaucu acaugcacgu gcccaagagc ggcgcccuga     2580

accagaaggu gguguucuac ggcaagggca ccuacgaccc cgacggcagc aucgccggcu     2640

accaguggga cuucggcgac ggcagcgacu ucagcagcga gcagaacccc agccacgugu     2700

acaccaagaa gggcgaguac accgugaccc ugagagugau ggacagcagc ggccagauga     2760

gcgagaagac caugaagauc aagaucaccg accccgugua ccccaucggc accgagaagg     2820

agcccaacaa cagcaaggag accgccagcg gccccaucgu gcccggcauc cccgugagcg     2880

gcaccaucga gaacaccagc gaccaggacu acuucuacuu cgacgugauc acccccggcg     2940

aggugaagau cgacaucaac aagcugggcu acggcggcgc caccugggug guguacgacg     3000

agaacaacaa cgccgugagc uacgccaccg acgacggcca gaaccugagc ggcaaguuca     3060

aggccgacaa gcccggcaga uacuacaucc accuguacau guucaacggc agcuacaugc     3120

ccuacagaau caacaucgag ggcagcgugg gcagaugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  2976
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt4)

<400>  2976
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

gaaagugccu gagcaagaga cugaugcugg ccaucaccau ggccaccauc uucaccguga      120

acagcacccu gcccaucuac gccgccgugg acaagaacaa cgccaccgcc gccgugcaga      180

acgagagcaa gagauacacc gugagcuacc ugaagacccu gaacuacuac gaccuggugg      240

accugcuggu gaagaccgag aucgagaacc ugcccgaccu guuccaguac agcagcgacg      300

ccaaggaguu cuacggcaac aagaccagaa ugagcuucau cauggacgag aucggcagaa      360

gagcccccca guacaccgag aucgaccaca agggcauccc cacccuggug gaggugguga      420

gagccggcuu cuaccugggc uuccacaaca aggagcugaa cgagaucaac aagagaagcu      480

ucaaggagag agugaucccc agcauccugg ccauccagaa gaaccccaac uucaagcugg      540

gcaccgaggu gcaggacaag aucgugagcg ccaccggccu gcuggccggc aacgagaccg      600

ccccccccga gguggugaac aacuucaccc ccauccugca ggacugcauc aagaacaucg      660

acagauacgc ccuggacgac cugaagagca aggcccuguu caacgugcug gccgccccca      720

ccuacgacau caccgaguac cugagagcca ccaaggagaa gcccgagaac acccccuggu      780

acggcaagau cgacggcuuc aucaacgagc ugaagaagcu ggcccuguac ggcaagauca      840

acgacaacaa cagcuggauc aucgacaacg gcaucuacca caucgccccc cugggcaagc      900

ugcacagcaa caacaagauc ggcaucgaga cccugaccga ggugaugaag guguaccccu      960

accugagcau gcagcaccug cagagcgccg accagaucaa gagacacuac gacagcaagg     1020

acgccgaggg caacaagauc ccccuggaca aguucaagaa ggagggcaag gagaaguacu     1080

gccccaagac cuacaccuuc gacgacggca aggugaucau caaggccggc gccagagugg     1140

aggaggagaa ggugaagaga cuguacuggg ccagcaagga ggugaacagc caguucuuca     1200

gaguguacgg caucgacaag ccccuggagg agggcaaccc cgacgacauc cugaccaugg     1260

ugaucuacaa cagccccgag gaguacaagc ugaacagcgu gcuguacggc uacgacacca     1320

acaacggcgg cauguacauc gagcccgagg gcaccuucuu caccuacgag agagaggccc     1380

aggagagcac cuacacccug gaggagcugu ucagacacga guacacccac uaccugcagg     1440

gcagauacgc cgugcccggc caguggggca gaaccaagcu guacgacaac gacagacuga     1500

ccugguacga ggagggcggc gccgagcugu ucgccggcag caccagaacc agcggcaucc     1560

ugcccagaaa gagcaucgug agcaacaucc acaacaccac cagaaacaac agauacaagc     1620

ugagcgacac cgugcacagc aaguacggcg ccagcuucga guucuacaac uacgccugca     1680

uguucaugga cuacauguac aacaaggaca ugggcauccu gaacaagcug aacgaccugg     1740

ccaagaacaa cgacguggac ggcuacgaca acuacaucag agaccugagc agcaacuacg     1800

cccugaacga caaguaccag gaccacaugc aggagagaau cgacaacuac gagaaccuga     1860

ccgugcccuu cguggccgac gacuaccugg ugagacacgc cuacaagaac cccaacgaga     1920

ucuacagcga gaucagcgag guggccaagc ugaaggacgc caagagcgag gugaagaaga     1980

gccaguacuu cagcaccuuc acccugagag gcagcuacac cggcggcgcc agcaagggca     2040

agcuggagga ccagaaggcc augaacaagu ucaucgacga cagccugaag aagcuggaca     2100

ccuacagcug gagcggcuac aagacccuga ccgccuacuu caccaacuac aagguggaca     2160

gcagcaacag agugaccuac gacguggugu uccacggcua ccugcccaac gagggcgaca     2220

gcaagaacag ccugcccuac ggcaagauca acggcaccua caagggcacc gagaaggaga     2280

agaucaaguu cagcagcgag ggcagcuucg accccgacgg caagaucgug agcuacgagu     2340

gggacuucgg cgacggcaac aagagcaacg aggagaaccc cgagcacagc uacgacaagg     2400

ugggcaccua caccgugaag cugaagguga ccgacgacaa gggcgagagc agcgugagca     2460

ccaccaccgc cgagaucaag gaccugagcg agaacaagcu gcccgugauc uacaugcacg     2520

ugcccaagag cggcgcccug aaccagaagg ugguguucua cggcaagggc accuacgacc     2580

ccgacggcag caucgccggc uaccaguggg acuucggcga cggcagcgac uucagcagcg     2640

agcagaaccc cagccacgug uacaccaaga agggcgagua caccgugacc cugagaguga     2700

uggacagcag cggccagaug agcgagaaga ccaugaagau caagaucacc gaccccgugu     2760

accccaucgg caccgagaag gagcccaaca acagcaagga gaccgccagc ggccccaucg     2820

ugcccggcau ccccgugagc ggcaccaucg agaacaccag cgaccaggac uacuucuacu     2880

ucgacgugau cacccccggc gaggugaaga ucgacaucaa caagcugggc uacggcggcg     2940

ccaccugggu gguguacgac gagaacaaca acgccgugag cuacgccacc gacgacggcc     3000

agaaccugag cggcaaguuc aaggccgaca agcccggcag auacuacauc caccuguaca     3060

uguucaacgg cagcuacaug cccuacagaa ucaacaucga gggcagcgug ggcagaugag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  2977
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt4)

<400>  2977
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cuguuccugu ucagcagcgc cuacagcgug cagaacgaga      120

gcaagagaua caccgugagc uaccugaaga cccugaacua cuacgaccug guggaccugc      180

uggugaagac cgagaucgag aaccugcccg accuguucca guacagcagc gacgccaagg      240

aguucuacgg caacaagacc agaaugagcu ucaucaugga cgagaucggc agaagagccc      300

cccaguacac cgagaucgac cacaagggca uccccacccu gguggaggug gugagagccg      360

gcuucuaccu gggcuuccac aacaaggagc ugaacgagau caacaagaga agcuucaagg      420

agagagugau ccccagcauc cuggccaucc agaagaaccc caacuucaag cugggcaccg      480

aggugcagga caagaucgug agcgccaccg gccugcuggc cggcaacgag accgcccccc      540

ccgagguggu gaacaacuuc acccccaucc ugcaggacug caucaagaac aucgacagau      600

acgcccugga cgaccugaag agcaaggccc uguucaacgu gcuggccgcc cccaccuacg      660

acaucaccga guaccugaga gccaccaagg agaagcccga gaacaccccc ugguacggca      720

agaucgacgg cuucaucaac gagcugaaga agcuggcccu guacggcaag aucaacgaca      780

acaacagcug gaucaucgac aacggcaucu accacaucgc cccccugggc aagcugcaca      840

gcaacaacaa gaucggcauc gagacccuga ccgaggugau gaagguguac cccuaccuga      900

gcaugcagca ccugcagagc gccgaccaga ucaagagaca cuacgacagc aaggacgccg      960

agggcaacaa gaucccccug gacaaguuca agaaggaggg caaggagaag uacugcccca     1020

agaccuacac cuucgacgac ggcaagguga ucaucaaggc cggcgccaga guggaggagg     1080

agaaggugaa gagacuguac ugggccagca aggaggugaa cagccaguuc uucagagugu     1140

acggcaucga caagccccug gaggagggca accccgacga cauccugacc auggugaucu     1200

acaacagccc cgaggaguac aagcugaaca gcgugcugua cggcuacgac accaacaacg     1260

gcggcaugua caucgagccc gagggcaccu ucuucaccua cgagagagag gcccaggaga     1320

gcaccuacac ccuggaggag cuguucagac acgaguacac ccacuaccug cagggcagau     1380

acgccgugcc cggccagugg ggcagaacca agcuguacga caacgacaga cugaccuggu     1440

acgaggaggg cggcgccgag cuguucgccg gcagcaccag aaccagcggc auccugccca     1500

gaaagagcau cgugagcaac auccacaaca ccaccagaaa caacagauac aagcugagcg     1560

acaccgugca cagcaaguac ggcgccagcu ucgaguucua caacuacgcc ugcauguuca     1620

uggacuacau guacaacaag gacaugggca uccugaacaa gcugaacgac cuggccaaga     1680

acaacgacgu ggacggcuac gacaacuaca ucagagaccu gagcagcaac uacgcccuga     1740

acgacaagua ccaggaccac augcaggaga gaaucgacaa cuacgagaac cugaccgugc     1800

ccuucguggc cgacgacuac cuggugagac acgccuacaa gaaccccaac gagaucuaca     1860

gcgagaucag cgagguggcc aagcugaagg acgccaagag cgaggugaag aagagccagu     1920

acuucagcac cuucacccug agaggcagcu acaccggcgg cgccagcaag ggcaagcugg     1980

aggaccagaa ggccaugaac aaguucaucg acgacagccu gaagaagcug gacaccuaca     2040

gcuggagcgg cuacaagacc cugaccgccu acuucaccaa cuacaaggug gacagcagca     2100

acagagugac cuacgacgug guguuccacg gcuaccugcc caacgagggc gacagcaaga     2160

acagccugcc cuacggcaag aucaacggca ccuacaaggg caccgagaag gagaagauca     2220

aguucagcag cgagggcagc uucgaccccg acggcaagau cgugagcuac gagugggacu     2280

ucggcgacgg caacaagagc aacgaggaga accccgagca cagcuacgac aaggugggca     2340

ccuacaccgu gaagcugaag gugaccgacg acaagggcga gagcagcgug agcaccacca     2400

ccgccgagau caaggaccug agcgagaaca agcugcccgu gaucuacaug cacgugccca     2460

agagcggcgc ccugaaccag aagguggugu ucuacggcaa gggcaccuac gaccccgacg     2520

gcagcaucgc cggcuaccag ugggacuucg gcgacggcag cgacuucagc agcgagcaga     2580

accccagcca cguguacacc aagaagggcg aguacaccgu gacccugaga gugauggaca     2640

gcagcggcca gaugagcgag aagaccauga agaucaagau caccgacccc guguacccca     2700

ucggcaccga gaaggagccc aacaacagca aggagaccgc cagcggcccc aucgugcccg     2760

gcauccccgu gagcggcacc aucgagaaca ccagcgacca ggacuacuuc uacuucgacg     2820

ugaucacccc cggcgaggug aagaucgaca ucaacaagcu gggcuacggc ggcgccaccu     2880

ggguggugua cgacgagaac aacaacgccg ugagcuacgc caccgacgac ggccagaacc     2940

ugagcggcaa guucaaggcc gacaagcccg gcagauacua cauccaccug uacauguuca     3000

acggcagcua caugcccuac agaaucaaca ucgagggcag cgugggcaga ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  2978
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt4)

<400>  2978
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cuguuccugu ucagcagcgc cuacagcaug aagagaaagu      120

gccugagcaa gagacugaug cuggccauca ccauggccac caucuucacc gugaacagca      180

cccugcccau cuacgccgcc guggacaaga acaacgccac cgccgccaga agaagaagaa      240

agagagugca gaacgagagc aagagauaca ccgugagcua ccugaagacc cugaacuacu      300

acgaccuggu ggaccugcug gugaagaccg agaucgagaa ccugcccgac cuguuccagu      360

acagcagcga cgccaaggag uucuacggca acaagaccag aaugagcuuc aucauggacg      420

agaucggcag aagagccccc caguacaccg agaucgacca caagggcauc cccacccugg      480

uggagguggu gagagccggc uucuaccugg gcuuccacaa caaggagcug aacgagauca      540

acaagagaag cuucaaggag agagugaucc ccagcauccu ggccauccag aagaacccca      600

acuucaagcu gggcaccgag gugcaggaca agaucgugag cgccaccggc cugcuggccg      660

gcaacgagac cgcccccccc gaggugguga acaacuucac ccccauccug caggacugca      720

ucaagaacau cgacagauac gcccuggacg accugaagag caaggcccug uucaacgugc      780

uggccgcccc caccuacgac aucaccgagu accugagagc caccaaggag aagcccgaga      840

acacccccug guacggcaag aucgacggcu ucaucaacga gcugaagaag cuggcccugu      900

acggcaagau caacgacaac aacagcugga ucaucgacaa cggcaucuac cacaucgccc      960

cccugggcaa gcugcacagc aacaacaaga ucggcaucga gacccugacc gaggugauga     1020

agguguaccc cuaccugagc augcagcacc ugcagagcgc cgaccagauc aagagacacu     1080

acgacagcaa ggacgccgag ggcaacaaga ucccccugga caaguucaag aaggagggca     1140

aggagaagua cugccccaag accuacaccu ucgacgacgg caaggugauc aucaaggccg     1200

gcgccagagu ggaggaggag aaggugaaga gacuguacug ggccagcaag gaggugaaca     1260

gccaguucuu cagaguguac ggcaucgaca agccccugga ggagggcaac cccgacgaca     1320

uccugaccau ggugaucuac aacagccccg aggaguacaa gcugaacagc gugcuguacg     1380

gcuacgacac caacaacggc ggcauguaca ucgagcccga gggcaccuuc uucaccuacg     1440

agagagaggc ccaggagagc accuacaccc uggaggagcu guucagacac gaguacaccc     1500

acuaccugca gggcagauac gccgugcccg gccagugggg cagaaccaag cuguacgaca     1560

acgacagacu gaccugguac gaggagggcg gcgccgagcu guucgccggc agcaccagaa     1620

ccagcggcau ccugcccaga aagagcaucg ugagcaacau ccacaacacc accagaaaca     1680

acagauacaa gcugagcgac accgugcaca gcaaguacgg cgccagcuuc gaguucuaca     1740

acuacgccug cauguucaug gacuacaugu acaacaagga caugggcauc cugaacaagc     1800

ugaacgaccu ggccaagaac aacgacgugg acggcuacga caacuacauc agagaccuga     1860

gcagcaacua cgcccugaac gacaaguacc aggaccacau gcaggagaga aucgacaacu     1920

acgagaaccu gaccgugccc uucguggccg acgacuaccu ggugagacac gccuacaaga     1980

accccaacga gaucuacagc gagaucagcg agguggccaa gcugaaggac gccaagagcg     2040

aggugaagaa gagccaguac uucagcaccu ucacccugag aggcagcuac accggcggcg     2100

ccagcaaggg caagcuggag gaccagaagg ccaugaacaa guucaucgac gacagccuga     2160

agaagcugga caccuacagc uggagcggcu acaagacccu gaccgccuac uucaccaacu     2220

acaaggugga cagcagcaac agagugaccu acgacguggu guuccacggc uaccugccca     2280

acgagggcga cagcaagaac agccugcccu acggcaagau caacggcacc uacaagggca     2340

ccgagaagga gaagaucaag uucagcagcg agggcagcuu cgaccccgac ggcaagaucg     2400

ugagcuacga gugggacuuc ggcgacggca acaagagcaa cgaggagaac cccgagcaca     2460

gcuacgacaa ggugggcacc uacaccguga agcugaaggu gaccgacgac aagggcgaga     2520

gcagcgugag caccaccacc gccgagauca aggaccugag cgagaacaag cugcccguga     2580

ucuacaugca cgugcccaag agcggcgccc ugaaccagaa ggugguguuc uacggcaagg     2640

gcaccuacga ccccgacggc agcaucgccg gcuaccagug ggacuucggc gacggcagcg     2700

acuucagcag cgagcagaac cccagccacg uguacaccaa gaagggcgag uacaccguga     2760

cccugagagu gauggacagc agcggccaga ugagcgagaa gaccaugaag aucaagauca     2820

ccgaccccgu guaccccauc ggcaccgaga aggagcccaa caacagcaag gagaccgcca     2880

gcggccccau cgugcccggc auccccguga gcggcaccau cgagaacacc agcgaccagg     2940

acuacuucua cuucgacgug aucacccccg gcgaggugaa gaucgacauc aacaagcugg     3000

gcuacggcgg cgccaccugg gugguguacg acgagaacaa caacgccgug agcuacgcca     3060

ccgacgacgg ccagaaccug agcggcaagu ucaaggccga caagcccggc agauacuaca     3120

uccaccugua cauguucaac ggcagcuaca ugcccuacag aaucaacauc gagggcagcg     3180

ugggcagaug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  2979
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt4)

<400>  2979
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cugcugggcg ccgccuucgc caugccccug cccccccacc      120

ccggccaccc cggcuacauc aacuucagcu acgaggugcu gaccccccug aagugguacc      180

agagcaucag accccccuac cccagcuacg gcuacgagcc caugggcggc uggcugcacc      240

accagaucau ccccgugcug agccagcagc acccccccac ccacacccug cagccccacc      300

accacauccc cguggugccc gcccagcagc ccgugauccc ccagcagccc augaugcccg      360

ugcccggcca gcacagcaug acccccaucc agcaccacca gcccaaccug cccccccccg      420

cccagcagcc cuaccagccc cagcccgugc agccccagcc ccaccagccc augcagcccc      480

agccccccgu gcaccccaug cagccccugc ccccccagcc cccccugccc cccauguucc      540

ccaugcagcc ccugcccccc augcugcccg accugacccu ggaggccugg cccagcaccg      600

acaagaccaa gagagaggag guggacugag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  2980
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt4)

<400>  2980
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug cugacccccc      120

ugaaguggua ccagagcauc agaccccccu accccagcua cggcuacgag cccaugggcg      180

gcuggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  2981
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt4)

<400>  2981
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug cugacccccc      120

ugaaguggua ccagagcauc agaccccccc ccaugcugcc cgaccugacc cuggaggccu      180

ggcccagcac cgacaagacc aagagagagg agguggacug aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  2982
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt4)

<400>  2982
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcccc cagaacccug gugcugcugc ugagcggcgc ccuggcccug acccagaccu      120

gggccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagagca ucagaccccc cuaccccagc uacggcuacg      240

agcccauggg cggcugguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  2983
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt4)

<400>  2983
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcccc cagaacccug gugcugcugc ugagcggcgc ccuggcccug acccagaccu      120

gggccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagagca ucagaccccc ccccaugcug cccgaccuga      240

cccuggaggc cuggcccagc accgacaaga ccaagagaga ggagguggac ugaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  2984
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt4)

<400>  2984
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuggugggcg ccgccuucgc caugccccug cccccccacc      120

ccggccaccc cggcuacauc aacuucagcu acgaggugcu gaccccccug aagugguacc      180

agagcaugau cagacccccc uacagcagcu acggcuacga gcccaugggc ggcuggcugc      240

accaccagau cauccccgug gugagccagc agcacccccu gacccacacc cugcagagcc      300

accaccacau ccccguggug cccgcccagc agcccagagu gagacagcag gcccugaugc      360

ccgugcccgg ccagcagagc augaccccca cccagcacca ccagcccaac cugccccugc      420

ccgcccagca gcccuuccag ccccagcccg ugcagcccca gccccaccag cccaugcagc      480

cccagccccc cgugcagccc augcagcccc ugcugcccca gcccccccug ccccccaugu      540

ucccccugag accccugccc cccauccugc ccgaccugca ccuggaggcc uggcccgcca      600

ccgacaagac caagcaggag gagguggacu gaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  2985
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt4)

<400>  2985
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug cugacccccc      120

ugaaguggua ccagagcaug aucagacccc ccuacagcag cuacggcuac gagcccaugg      180

gcggcuggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  2986
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt4)

<400>  2986
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug cugacccccc      120

ugaaguggua ccagagcaug aucagacccc cccccauccu gcccgaccug caccuggagg      180

ccuggcccgc caccgacaag accaagcagg aggaggugga cugaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  2987
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt4)

<400>  2987
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcccc cagaacccug gugcugcugc ugagcggcgc ccuggcccug acccagaccu      120

gggccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagagca ugaucagacc ccccuacagc agcuacggcu      240

acgagcccau gggcggcugg ugaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  2988
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt4)

<400>  2988
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcccc cagaacccug gugcugcugc ugagcggcgc ccuggcccug acccagaccu      120

gggccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagagca ugaucagacc cccccccauc cugcccgacc      240

ugcaccugga ggccuggccc gccaccgaca agaccaagca ggaggaggug gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  2989
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt4)

<400>  2989
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cugcugggcg ccgccuucag caugccccug cccccccacc      120

ccggccaccc cggcuacauc aacuucagcu acgaggugcu gaccccccug aagugguacc      180

agaacaugau cagacacccc uacaccagcu acggcuacga gcccaugggc ggcuggcugc      240

accaccagau cauccccgug gugagccagc agacccccca gagccacgcc cugcagcccc      300

accaccacau ccccauggug cccgcccagc agcccggcau cccccagcag cccaugaugc      360

cccugcccgg ccagcacagc augaccccca cccagcacca ccagcccaac cugccccugc      420

ccgcccagca gcccuuccag ccccagcccg ugcagcccca gccccaccag ccccugcagc      480

cccagagccc caugcacccc auccagcccc ugcugcccca gcccccccug ccccccaugu      540

ucagcaugca gagccugcug cccgaccugc cccuggaggc cuggcccgcc accgacaaga      600

ccaagagaga ggagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  2990
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt4)

<400>  2990
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug cugacccccc      120

ugaaguggua ccagaacaug aucagacacc ccuacaccag cuacggcuac gagcccaugg      180

gcggcuggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  2991
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt4)

<400>  2991
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug cugacccccc      120

ugaaguggua ccagaacaug aucagacacc ccagccugcu gcccgaccug ccccuggagg      180

ccuggcccgc caccgacaag accaagagag aggaggugga cugaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  2992
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt4)

<400>  2992
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcccc cagaacccug gugcugcugc ugagcggcgc ccuggcccug acccagaccu      120

gggccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccuacacc agcuacggcu      240

acgagcccau gggcggcugg ugaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  2993
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt4)

<400>  2993
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcccc cagaacccug gugcugcugc ugagcggcgc ccuggcccug acccagaccu      120

gggccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccagccug cugcccgacc      240

ugccccugga ggccuggccc gccaccgaca agaccaagag agaggaggug gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  2994
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt4)

<400>  2994
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cugcugggcg ccgccuucag caugccccug cccccccacc      120

ccggccaccc cggcuacauc aacuucagcu acaucagaca ccccuacacc agcuacggcu      180

acgagcccau gggcggcugg cugcaccacc agaucauccc cguggugagc cagcagaccc      240

cccagagcca cgcccugcag ccccaccacc acauccccau ggugcccgcc cagcagcccg      300

gcauccccca gcagcccaug augccccugc ccggccagca cagcaugacc cccacccagc      360

accaccagcc caaccugccc cugcccgccc agcagcccuu ccagccccag cccgugcagc      420

cccagcccca ccagccccug cagccccaga gccccaugca ccccauccag ccccugcugc      480

cccagccccc ccugcccccc auguucagca ugcagagccu gcugcccgac cugccccugg      540

aggccuggcc cgccaccgac aagaccaaga gagaggaggu ggacugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  2995
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt4)

<400>  2995
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggaucuu cuucgccugc cugcugggcg ccagccuggc caugccccug cccccccacc      120

ccggccaccc cggcuacauc aacuucagcu acgaggugcu gaccccccug aagugguacc      180

agaacaugau cagacacccc uacaccagcu acggcuacga gcccaugggc ggcuggcugc      240

accaccagau cauccccgug gugagccagc agacccccca gagccacgcc cugcagcccc      300

accaccacau ccccauggug cccgcccagc agcccggcau cccccagcag cccaugaugc      360

cccugcccgg ccagcacagc augaccccca cccagcacca ccagcccaac cugccccugc      420

ccgcccagca gcccuuccag ccccagcccg ugcagcccca gccccaccag ccccugcagc      480

cccagagccc caugcacccc auccagcccc ugcugcccca gcccccccug ccccccaugu      540

ucagcaugca gagccugcug cccgaccugc cccuggaggc cuggcccgcc accgacaaga      600

ccaagagaga ggagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  2996
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt4)

<400>  2996
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cugcugggcg ccgccuucag caugccccug cccccccacc      120

ccggccaccc cggcuacauc aacuucagcu acgaggugcu gaccccccug aagugguacc      180

agaacaugau cagacacccc agccugcugc ccgaccugcc ccuggaggcc uggcccgcca      240

ccgacaagac caagagagag gagguggacu gaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  2997
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt4)

<400>  2997
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cugcugggcg ccgccuucag caugccccug cccccccacc      120

ccggccaccc cggcuacauc aacuucagcu acgaggaccu guaccuggag gccaucagaa      180

ucgacagaac cgccuucgug cugacccccc ugaaguggua ccagaacaug aucagacacc      240

ccuacaccag cuacggcuac gagcccaugg gcggcuggcu gcaccaccag aucauccccg      300

uggugagcca gcagaccccc cagagccacg cccugcagcc ccaccaccac auccccaugg      360

ugcccgccca gcagcccggc aucccccagc agcccaugau gccccugccc ggccagcaca      420

gcaugacccc cacccagcac caccagccca accugccccu gcccgcccag cagcccuucc      480

agccccagcc cgugcagccc cagccccacc agccccugca gccccagagc cccaugcacc      540

ccauccagcc ccugcugccc cagccccccc ugccccccau guucagcaug cagagccugc      600

ugcccgaccu gccccuggag gccuggcccg ccaccgacaa gaccaagaga gaggaggugg      660

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  2998
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt4)

<400>  2998
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cugcugggcg ccgccuucag caugccccug cccccccacc      120

ccggccaccc cggcuacauc aacuucagcu acgaggugcu gaccccccug aagugguacc      180

agaacaugau cagacacccc accccccaga gccacgcccu gcagccccac caccacaucc      240

ccauggugcc cgcccagcag cccggcaucc cccagcagcc caugaugccc cugcccggcc      300

agcacagcau gacccccacc cagcaccacc agcccaaccu gccccugccc gcccagcagc      360

ccuuccagcc ccagcccgug cagccccagc cccaccagcc ccugcagccc cagagcccca      420

ugcaccccau ccagccccug cugccccagc ccccccugcc ccccauguuc agcaugcaga      480

gccugcugcc cgaccugccc cuggaggccu ggcccgccac cgacaagacc aagagagagg      540

agguggacug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  2999
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt4)

<400>  2999
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccccccca ccccggccac cccggcuaca ucaacuucag cuacgaggug cugacccccc      120

ugaaguggua ccagaacaug aucagacacc ccuacaccag cuacggcuac gagcccaugg      180

gcggcuggcu gcaccaccag aucauccccg uggugagcca gcagaccccc cagagccacg      240

cccugcagcc ccaccaccac auccccaugg ugcccgccca gcagcccggc aucccccagc      300

agcccaugau gccccugccc ggccagcaca gcaugacccc cacccagcac caccagccca      360

accugccccu gcccgcccag cagcccuucc agccccagcc cgugcagccc cagccccacc      420

agccccugca gccccagagc cccaugcacc ccauccagcc ccugcugccc cagccccccc      480

ugccccccau guucagcaug cagagccugc ugcccgaccu gccccuggag gccuggcccg      540

ccaccgacaa gaccaagaga gaggaggugg acugaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  3000
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt4)

<400>  3000
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gcguggccag acugccccug cugcugggcc ugcugcugcu gcccagaccc ggcagacccc      120

uggaccuggc cgacuacacc uacgaccugg ccgaggagga cgacagcgag ccccugaacu      180

acaaggaccc cugcaaggcc gccgccuucc ugggcgacau cgcccuggac gaggaggacc      240

ugagagccuu ccaggugcag caggccgugg accugagaag acacaccgcc agaaagagca      300

gcaucaaggc cgccgugccc ggcaacacca gcacccccag cugccagagc accaacggcc      360

agccccagag aggcgccugc ggcagaugga gaggcagaag cagaagcaga agagccgcca      420

ccagcagacc cgagagagug uggcccgacg gcgugauccc cuucgugauc ggcggcaacu      480

ucaccggcag ccagagagcc guguucagac aggccaugag acacugggag aagcacaccu      540

gcgugaccuu ccuggagaga accgacgagg acagcuacau cguguucacc uacagacccu      600

gcggcugcug cagcuacgug ggcagaagag gcggcggccc ccaggccauc agcaucggca      660

agaacugcga caaguucggc aucguggugc acgagcuggg ccacguggug ggcuucuggc      720

acgagcacac cagacccgac agagacagac acgugagcau cgugagagag aacauccagc      780

ccggccagga guacaacuuc cugaagaugg agccccagga gguggagagc cugggcgaga      840

ccuacgacuu cgacagcauc augcacuacg ccagaaacac cuucagcaga ggcaucuucc      900

uggacaccau cgugcccaag uacgagguga acggcgugaa gccccccauc ggccagagaa      960

ccagacugag caagggcgac aucgcccagg ccagaaagcu guacaagugc cccgccugcg     1020

gcgagacccu gcaggacagc accggcaacu ucagcagccc cgaguacccc aacggcuaca     1080

gcgcccacau gcacugcgug uggagaauca gcgugacccc cggcgagaag aucauccuga     1140

acuucaccag ccuggaccug uacagaagca gacugugcug guacgacuac guggagguga     1200

gagacggcuu cuggagaaag gccccccuga gaggcagauu cugcggcagc aagcugcccg     1260

agcccaucgu gagcaccgac agcagacugu ggguggaguu cagaagcagc agcaacuggg     1320

ugggcaaggg cuucuucgcc guguacgagg ccaucugcgg cggcgacgug aagaaggacu     1380

acggccacau ccagagcccc aacuaccccg acgacuacag acccagcaag gugugcaucu     1440

ggagaaucca ggugagcgag ggcuuccacg ugggccugac cuuccagagc uucgagaucg     1500

agagacacga cagcugcgcc uacgacuacc uggaggugag agacggccac agcgagagca     1560

gcacccugau cggcagauac ugcggcuacg agaagcccga cgacaucaag agcaccagca     1620

gcagacugug gcugaaguuc gugagcgacg gcagcaucaa caaggccggc uucgccguga     1680

acuucuucaa ggagguggac gagugcagca gacccaacag aggcggcugc gagcagagau     1740

gccugaacac ccugggcagc uacaagugca gcugcgaccc cggcuacgag cuggcccccg     1800

acaagagaag augcgaggcc gccugcggcg gcuuccugac caagcugaac ggcagcauca     1860

ccagccccgg cuggcccaag gaguaccccc ccaacaagaa cugcaucugg cagcuggugg     1920

cccccaccca guacagaauc agccugcagu ucgacuucuu cgagaccgag ggcaacgacg     1980

ugugcaagua cgacuucgug gaggugagaa gcggccugac cgccgacagc aagcugcacg     2040

gcaaguucug cggcagcgag aagcccgagg ugaucaccag ccaguacaac aacaugagag     2100

uggaguucaa gagcgacaac accgugagca agaagggcuu caaggcccac uucuucagcg     2160

acaaggacga gugcagcaag gacaacggcg gcugccagca ggacugcgug aacaccuucg     2220

gcagcuacga gugccagugc agaagcggcu ucgugcugca cgacaacaag cacgacugca     2280

aggaggccgg cugcgaccac aaggugacca gcaccagcgg caccaucacc agccccaacu     2340

ggcccgacaa guaccccagc aagaaggagu gcaccugggc caucagcagc acccccggcc     2400

acagagugaa gcugaccuuc auggagaugg acaucgagag ccagcccgag ugcgccuacg     2460

accaccugga gguguucgac ggcagagacg ccaaggcccc cgugcugggc agauucugcg     2520

gcagcaagaa gcccgagccc gugcuggcca ccggcagcag aauguuccug agauucuaca     2580

gcgacaacag cgugcagaga aagggcuucc aggccagcca cgccaccgag ugcggcggcc     2640

aggugagagc cgacgugaag accaaggacc uguacagcca cgcccaguuc ggcgacaaca     2700

acuaccccgg cggcguggac ugcgaguggg ugaucguggc cgaggagggc uacggcgugg     2760

agcugguguu ccagaccuuc gagguggagg aggagaccga cugcggcuac gacuacaugg     2820

agcuguucga cggcuacgac agcaccgccc ccagacuggg cagauacugc ggcagcggcc     2880

cccccgagga gguguacagc gccggcgaca gcgugcuggu gaaguuccac agcgacgaca     2940

ccaucaccaa gaagggcuuc caccugagau acaccagcac caaguuccag gacacccugc     3000

acagcagaaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  3001
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt4)

<400>  3001
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

ccggcaccag augccugcug gcccugcugc ugccccaggu gcugcugggc ggcgccgccg      120

gccuggugcc cgagcugggc agaagaaagu ucgccgccgc cagcagcggc agacccagca      180

gccagcccag cgacgaggug cugagcgagu ucgagcugag acugcugagc auguucggcc      240

ugaagcagag acccaccccc agcagagacg ccguggugcc ccccuacaug cuggaccugu      300

acagaagaca cagcggccag cccggcagcc ccgcccccga ccacagacug gagagagccg      360

ccagcagagc caacaccgug agaagcuucc accacgagga gagccuggag gagcugcccg      420

agaccagcgg caagaccacc agaagauucu ucuucaaccu gagcagcauc cccaccgagg      480

aguucaucac cagcgccgag cugcaggugu ucagagagca gaugcaggac gcccugggca      540

acaacagcag cuuccaccac agaaucaaca ucuacgagau caucaagccc gccaccgcca      600

acagcaaguu ccccgugacc agacugcugg acaccagacu ggugaaccag aacgccagca      660

gaugggagag cuucgacgug acccccgccg ugaugagaug gaccgcccag ggccacgcca      720

accacggcuu cgugguggag guggcccacc uggaggagaa gcagggcgug agcaagagac      780

acgugagaau cagcagaagc cugcaccagg acgagcacag cuggagccag aucagacccc      840

ugcuggugac cuucggccac gacggcaagg gccacccccu gcacaagaga gagaagagac      900

aggccaagca caagcagaga aagagacuga agagcagcug caagagacac ccccuguacg      960

uggacuucag cgacgugggc uggaacgacu ggaucguggc cccccccggc uaccacgccu     1020

ucuacugcca cggcgagugc cccuuccccc uggccgacca ccugaacagc accaaccacg     1080

ccaucgugca gacccuggug aacagcguga acagcaagau ccccaaggcc ugcugcgugc     1140

ccaccgagcu gagcgccauc agcaugcugu accuggacga gaacgagaag guggugcuga     1200

agaacuacca ggacauggug guggagggcu gcggcugcag augaggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  3002
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt4)

<400>  3002
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaucc       60

ccggcaacag aaugcugaug guggugcugc ugugccaggu gcugcugggc ggcgccagcc      120

acgccagccu gauccccgag accggcaaga agaagguggc cgagauccag ggccacgccg      180

gcggcagaag aagcggccag agccacgagc ugcugagaga cuucgaggcc acccugcugc      240

agauguucgg ccugagaaga agaccccagc ccagcaagag cgccgugauc cccgacuaca      300

ugagagaccu guacagacug cagagcggcg aggaggagga ggagcagauc cacagcaccg      360

gccuggagua ccccgagaga cccgccagca gagccaacac cgugagaagc uuccaccacg      420

aggagcaccu ggagaacauc cccggcacca gcgagaacag cgccuucaga uuccuguuca      480

accugagcag cauccccgag aacgagguga ucagcagcgc cgagcugaga cuguucagag      540

agcaggugga ccagggcccc gacugggaga gaggcuucca cagaaucaac aucuacgagg      600

ugaugaagcc ccccgccgag guggugcccg gccaccugau caccagacug cuggacacca      660

gacuggugca ccacaacgug accagauggg agaccuucga cgugagcccc gccgugcuga      720

gauggaccag agagaagcag cccaacuacg gccuggccau cgaggugacc caccugcacc      780

agaccagaac ccaccagggc cagcacguga gaaucagcag aagccugccc cagggcagcg      840

gcaacugggc ccagcugaga ccccugcugg ugaccuucgg ccacgacggc agaggccacg      900

cccugaccag aagaagaaga gccaagagaa gccccaagca ccacagccag agagccagaa      960

agaagaacaa gaacugcaga agacacagcc uguacgugga cuucagcgac gugggcugga     1020

acgacuggau cguggccccc cccggcuacc aggccuucua cugccacggc gacugccccu     1080

ucccccuggc cgaccaccug aacagcacca accacgccau cgugcagacc cuggugaaca     1140

gcgugaacag cagcaucccc aaggccugcu gcgugcccac cgagcugagc gccaucagca     1200

ugcuguaccu ggacgaguac gacaaggugg ugcugaagaa cuaccaggag augguggugg     1260

agggcugcgg cugcagauga ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  3003
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt4)

<400>  3003
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gccugggcag aagagcccag uggcugugcu gguggugggg ccugcugugc agcugcugcg      120

gccccccccc ccugagaccc ccccugcccg ccgccgccgc cgccgccgcc ggcggccagc      180

ugcugggcga cggcggcagc cccggcagaa ccgagcagcc cccccccagc ccccagagca      240

gcagcggcuu ccuguacaga agacugaaga cccaggagaa gagagagaug cagaaggaga      300

uccugagcgu gcugggccug ccccacagac ccagaccccu gcacggccug cagcagcccc      360

agccccccgc ccugagacag caggaggagc agcagcagca gcagcagcug cccagaggcg      420

agcccccccc cggcagacug aagagcgccc cccuguucau gcuggaccug uacaacgccc      480

ugagcgccga caacgacgag gacggcgcca gcgagggcga gagacagcag agcuggcccc      540

acgaggccgc cagcagcagc cagagaagac agcccccccc cggcgccgcc cacccccuga      600

acagaaagag ccugcuggcc cccggcagcg gcagcggcgg cgccagcccc cugaccagcg      660

cccaggacag cgccuuccug aacgacgccg acauggugau gagcuucgug aaccuggugg      720

aguacgacaa ggaguucagc cccagacaga gacaccacaa ggaguucaag uucaaccuga      780

gccagauccc cgagggcgag guggugaccg ccgccgaguu cagaaucuac aaggacugcg      840

ugaugggcag cuucaagaac cagaccuucc ugaucagcau cuaccaggug cugcaggagc      900

accagcacag agacagcgac cuguuccugc uggacaccag aguggugugg gccagcgagg      960

agggcuggcu ggaguucgac aucaccgcca ccagcaaccu guggguggug accccccagc     1020

acaacauggg ccugcagcug agcgugguga ccagagacgg cgugcacgug caccccagag     1080

ccgccggccu ggugggcaga gacggccccu acgacaagca gcccuucaug guggccuucu     1140

ucaaggugag cgaggugcac gugagaacca ccagaagcgc cagcagcaga agaagacagc     1200

agagcagaaa cagaagcacc cagagccagg acguggccag agugagcagc gccagcgacu     1260

acaacagcag cgagcugaag accgccugca gaaagcacga gcuguacgug agcuuccagg     1320

accugggcug gcaggacugg aucaucgccc ccaagggcua cgccgccaac uacugcgacg     1380

gcgagugcag cuucccccug aacgcccaca ugaacgccac caaccacgcc aucgugcaga     1440

cccuggugca ccugaugaac cccgaguacg ugcccaagcc cugcugcgcc cccaccaagc     1500

ugaacgccau cagcgugcug uacuucgacg acaacagcaa cgugauccug aagaaguaca     1560

gaaacauggu ggugagagcc ugcggcugcc acugaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  3004
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt4)

<400>  3004
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

ugagaagccu gagagccgcc gccccccaca gcuucguggc ccugugggcc ccccuguucc      120

ugcugagaag cgcccuggcc gacuucagcc uggacaacga ggugcacagc agcuucaucc      180

acagaagacu gagaagccag gagagaagag agaugcagag agagauccug agcauccugg      240

gccugcccca cagacccaga ccccaccugc agggcaagca caacagcgcc cccauguuca      300

ugcuggaccu guacaacgcc auggccgugg aggagggcgg cggccccggc ggccagggcu      360

ucagcuaccc cuacaaggcc guguucagca cccagggccc cccccuggcc agccugcagg      420

acagccacuu ccugaccgac gccgacaugg ugaugagcuu cgugaaccug guggagcacg      480

acaaggaguu cuuccacccc agauaccacc acagagaguu cagauucgac cugagcaaga      540

uccccgaggg cgaggccgug accgccgccg aguucagaau cuacaaggac uacaucagag      600

agagauucga caacgagacc uucagaauca gcguguacca ggugcugcag gagcaccugg      660

gcagagagag cgaccuguuc cugcuggaca gcagaacccu gugggccagc gaggagggcu      720

ggcugguguu cgacaucacc gccaccagca accacugggu ggugaacccc agacacaacc      780

ugggccugca gcugagcgug gagacccugg acggccagag caucaacccc aagcuggccg      840

gccugaucgg cagacacggc ccccagaaca agcagcccuu caugguggcc uucuucaagg      900

ccaccgaggu gcacuucaga agcaucagaa gcaccggcag caagcagaga agccagaaca      960

gaagcaagac ccccaagaac caggaggccc ugagaauggc caacguggcc gagaacagca     1020

gcagcgacca gagacaggcc ugcaagaagc acgagcugua cgugagcuuc agagaccugg     1080

gcuggcagga cuggaucauc gcccccgagg gcuacgccgc cuacuacugc gagggcgagu     1140

gcgccuuccc ccugaacagc uacaugaacg ccaccaacca cgccaucgug cagacccugg     1200

ugcacuucau caaccccgag accgugccca agcccugcug cgcccccacc cagcugaacg     1260

ccaucagcgu gcuguacuuc gacgacagca gcaacgugau ccugaagaag uacagaaaca     1320

ugguggugag agccugcggc ugccacugag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  3005
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt4)

<400>  3005
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagg       60

ccagcgccgc ccugcugugc cugcugcuga ccgccgccgc cuucagcccc cagggccugg      120

cccagcccgu gggcaucaac accagcacca ccugcugcua cagauucauc aacaagaaga      180

uccccaagca gagacuggag agcuacagaa gaaccaccag cagccacugc cccagagagg      240

ccgugaucuu caagaccaag cuggacaagg agaucugcgc cgaccccacc cagaaguggg      300

ugcaggacuu caugaagcac cuggacaaga agacccagac ccccaagcug ugaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  3006
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt4)

<400>  3006
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugc       60

ugacccugau cauccugcug cccgugguga gcaaguucag cuucgugagc cugagcgccc      120

cccagcacug gagcugcccc gagggcaccc uggccggcaa cggcaacagc accugcgugg      180

gccccgcccc cuuccugauc uucagccacg gcaacagcau cuucagaauc gacaccgagg      240

gcaccaacua cgagcagcug gugguggacg ccggcgugag cgugaucaug gacuuccacu      300

acaacgagaa gagaaucuac uggguggacc uggagagaca gcugcugcag agaguguucc      360

ugaacggcag cagacaggag agagugugca acaucgagaa gaacgugagc ggcauggcca      420

ucaacuggau caacgaggag gugaucugga gcaaccagca ggagggcauc aucaccguga      480

ccgacaugaa gggcaacaac agccacaucc ugcugagcgc ccugaaguac cccgccaacg      540

uggccgugga ccccguggag agauucaucu ucuggagcag cgagguggcc ggcagccugu      600

acagagccga ccuggacggc gugggcguga aggcccugcu ggagaccagc gagaagauca      660

ccgccgugag ccuggacgug cuggacaaga gacuguucug gauccaguac aacagagagg      720

gcagcaacag ccugaucugc agcugcgacu acgacggcgg cagcgugcac aucagcaagc      780

accccaccca gcacaaccug uucgccauga gccuguucgg cgacagaauc uucuacagca      840

ccuggaagau gaagaccauc uggaucgcca acaagcacac cggcaaggac auggugagaa      900

ucaaccugca cagcagcuuc gugccccugg gcgagcugaa gguggugcac ccccuggccc      960

agcccaaggc cgaggacgac accugggagc ccgagcagaa gcugugcaag cugagaaagg     1020

gcaacugcag cagcaccgug ugcggccagg accugcagag ccaccugugc augugcgccg     1080

agggcuacgc ccugagcaga gacagaaagu acugcgagga cgugaacgag ugcgccuucu     1140

ggaaccacgg cugcacccug ggcugcaaga acacccccgg cagcuacuac ugcaccugcc     1200

ccgugggcuu cgugcugcug cccgacggca agagaugcca ccagcuggug agcugcccca     1260

gaaacgugag cgagugcagc cacgacugcg ugcugaccag cgagggcccc cugugcuucu     1320

gccccgaggg cagcgugcug gagagagacg gcaagaccug cagcggcugc agcagccccg     1380

acaacggcgg cugcagccag cugugcgugc cccugagccc cgugagcugg gagugcgacu     1440

gcuuccccgg cuacgaccug cagcuggacg agaagagcug cgccgccagc ggcccccagc     1500

ccuuccugcu guucgccaac agccaggaca ucagacacau gcacuucgac ggcaccgacu     1560

acggcacccu gcugagccag cagaugggca ugguguacgc ccuggaccac gaccccgugg     1620

agaacaagau cuacuucgcc cacaccgccc ugaaguggau cgagagagcc aacauggacg     1680

gcagccagag agagagacug aucgaggagg gcguggacgu gcccgagggc cuggccgugg     1740

acuggaucgg cagaagauuc uacuggaccg acagaggcaa gagccugauc ggcagaagcg     1800

accugaacgg caagagaagc aagaucauca ccaaggagaa caucagccag cccagaggca     1860

ucgccgugca ccccauggcc aagagacugu ucuggaccga caccggcauc aaccccagaa     1920

ucgagagcag cagccugcag ggccugggca gacuggugau cgccagcagc gaccugaucu     1980

ggcccagcgg caucaccauc gacuuccuga ccgacaagcu guacuggugc gacgccaagc     2040

agagcgugau cgagauggcc aaccuggacg gcagcaagag aagaagacug acccagaacg     2100

acgugggcca ccccuucgcc guggccgugu ucgaggacua cgugugguuc agcgacuggg     2160

ccaugcccag cgugaugaga gugaacaaga gaaccggcaa ggacagagug agacugcagg     2220

gcagcaugcu gaagcccagc agccuggugg uggugcaccc ccuggccaag cccggcgccg     2280

accccugccu guaccagaac ggcggcugcg agcacaucug caagaagaga cugggcaccg     2340

ccuggugcag cugcagagag ggcuucauga aggccagcga cggcaagacc ugccuggccc     2400

uggacggcca ccagcugcug gccggcggcg agguggaccu gaagaaccag gugacccccc     2460

uggacauccu gagcaagacc agagugagcg aggacaacau caccgagagc cagcacaugc     2520

ugguggccga gaucauggug agcgaccagg acgacugcgc ccccgugggc ugcagcaugu     2580

acgccagaug caucagcgag ggcgaggacg ccaccugcca gugccugaag ggcuucgccg     2640

gcgacggcaa gcugugcagc gacaucgacg agugcgagau gggcgugccc gugugccccc     2700

ccgccagcag caagugcauc aacaccgagg gcggcuacgu gugcagaugc agcgagggcu     2760

accagggcga cggcauccac ugccuggaca ucgacgagug ccagcugggc gagcacagcu     2820

gcggcgagaa cgccagcugc accaacaccg agggcggcua caccugcaug ugcgccggca     2880

gacugagcga gcccggccug aucugccccg acagcacccc ccccccccac cugagagagg     2940

acgaccacca cuacagcgug agaaacagcg acagcgagug cccccugagc cacgacggcu     3000

acugccugca cgacggcgug ugcauguaca ucgaggcccu ggacaaguac gccugcaacu     3060

gcgugguggg cuacaucggc gagagaugcc aguacagaga ccugaagugg ugggagcuga     3120

gacacgccgg ccacggccag cagcagaagg ugaucguggu ggccgugugc gugguggugc     3180

uggugaugcu gcugcugcug agccuguggg gcgcccacua cuacagaacc cagaagcugc     3240

ugagcaagaa ccccaagaac cccuacgagg agagcagcag agacgugaga agcagaagac     3300

ccgccgacac cgaggacggc augagcagcu gcccccagcc cugguucgug gugaucaagg     3360

agcaccagga ccugaagaac ggcggccagc ccguggccgg cgaggacggc caggccgccg     3420

acggcagcau gcagcccacc agcuggagac aggagcccca gcugugcggc augggcaccg     3480

agcagggcug cuggaucccc gugagcagcg acaagggcag cugcccccag gugauggaga     3540

gaagcuucca caugcccagc uacggcaccc agacccugga gggcggcgug gagaagcccc     3600

acagccugcu gagcgccaac ccccuguggc agcagagagc ccuggacccc ccccaccaga     3660

uggagcugac ccagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  3007
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt4)

<400>  3007
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

ccggcagaag aauggagaug cugugcgccg gcagagugcc cgcccugcug cugugccugg      120

gcuuccaccu gcugcaggcc gugcugagca ccaccgugau ccccagcugc auccccggcg      180

agagcagcga caacugcacc gcccuggugc agaccgagga caaccccaga guggcccagg      240

ugagcaucac caagugcagc agcgacauga acggcuacug ccugcacggc cagugcaucu      300

accuggugga caugagccag aacuacugca gaugcgaggu gggcuacacc ggcgugagau      360

gcgagcacuu cuuccugacc gugcaccagc cccugagcaa ggaguacgug gcccugaccg      420

ugauccugau cauccuguuc cugaucaccg uggugggcag caccuacuac uucugcagau      480

gguacagaaa cagaaagagc aaggagccca agaaggagua cgagagagug accagcggcg      540

accccgagcu gccccaggug ugaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  3008
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt4)

<400>  3008
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

agggcgagau caccaccuuc accgcccuga ccgagaaguu caaccugccc cccggcaacu      120

acaagaagcc caagcugcug uacugcagca acggcggcca cuuccugaga auccugcccg      180

acggcaccgu ggacggcacc agagacagaa gcgaccagca cauccagcug cagcugagcg      240

ccgagagcgu gggcgaggug uacaucaaga gcaccgagac cggccaguac cuggccaugg      300

acaccgacgg ccugcuguac ggcagccaga cccccaacga ggagugccug uuccuggaga      360

gacuggagga gaaccacuac aacaccuaca ucagcaagaa gcacgccgag aagaacuggu      420

ucgugggccu gaagaagaac ggcagcugca agagaggccc cagaacccac uacggccaga      480

aggccauccu guuccugccc cugcccguga gcagcgacug aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  3009
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt4)

<400>  3009
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

gcgugggcgg cggcgacgug gaggacguga cccccagacc cggcggcugc cagaucagcg      120

gcagaggcgc cagaggcugc aacggcaucc ccggcgccgc cgccugggag gccgcccugc      180

ccagaagaag acccagaaga caccccagcg ugaaccccag aagcagagcc gccggcagcc      240

ccagaaccag aggcagaaga accgaggaga gacccagcgg cagcagacug ggcgacagag      300

gcagaggcag agcccugccc ggcggcagac ugggcggcag aggcagaggc agagcccccg      360

agagaguggg cggcagaggc agaggcagag gcaccgccgc ccccagagcc gcccccgccg      420

ccagaggcag cagacccggc cccgccggca ccauggccgc cggcagcauc accacccugc      480

ccgcccugcc cgaggacggc ggcagcggcg ccuucccccc cggccacuuc aaggacccca      540

agagacugua cugcaagaac ggcggcuucu uccugagaau ccaccccgac ggcagagugg      600

acggcgugag agagaagagc gacccccaca ucaagcugca gcugcaggcc gaggagagag      660

gcguggugag caucaagggc gugugcgcca acagauaccu ggccaugaag gaggacggca      720

gacugcuggc cagcaagugc gugaccgacg agugcuucuu cuucgagaga cuggagagca      780

acaacuacaa caccuacaga agcagaaagu acaccagcug guacguggcc cugaagagaa      840

ccggccagua caagcugggc agcaagaccg gccccggcca gaaggccauc cuguuccugc      900

ccaugagcgc caagagcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  3010
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt4)

<400>  3010
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aguggauccu gaccuggauc cugcccaccc ugcuguacag aagcugcuuc cacaucaucu      120

gccugguggg caccaucagc cuggccugca acgacaugac ccccgagcag auggccacca      180

acgugaacug cagcagcccc gagagacaca ccagaagcua cgacuacaug gagggcggcg      240

acaucagagu gagaagacug uucugcagaa cccaguggua ccugagaauc gacaagagag      300

gcaaggugaa gggcacccag gagaugaaga acaacuacaa caucauggag aucagaaccg      360

uggccguggg caucguggcc aucaagggcg uggagagcga guucuaccug gccaugaaca      420

aggagggcaa gcuguacgcc aagaaggagu gcaacgagga cugcaacuuc aaggagcuga      480

uccuggagaa ccacuacaac accuacgcca gcgccaagug gacccacaac ggcggcgaga      540

uguucguggc ccugaaccag aagggcaucc ccgugagagg caagaagacc aagaaggagc      600

agaagaccgc ccacuuccug cccauggcca ucaccugagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  3011
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt4)

<400>  3011
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ugcugcccag cguggugcug aagcuguucc uggccgccgu gcugagcgcc cuggugaccg      120

gcgagagccu ggagagacug agaagaggcc uggccgccgg caccagcaac cccgaccccc      180

ccaccgugag caccgaccag cugcugcccc ugggcggcgg cagagacaga aaggugagag      240

accugcagga ggccgaccug gaccugcuga gagugacccu gagcagcaag ccccaggccc      300

uggccacccc caacaaggag gagcacggca agagaaagaa gaagggcaag ggccugggca      360

agaagagaga ccccugccug agaaaguaca aggacuucug cauccacggc gagugcaagu      420

acgugaagga gcugagagcc cccagcugca ucugccaccc cggcuaccac ggcgagagau      480

gccacggccu gagccugccc guggagaaca gacuguacac cuacgaccac accaccaucc      540

uggccguggu ggccguggug cugagcagcg ugugccugcu ggugaucgug ggccugcuga      600

uguucagaua ccacagaaga ggcggcuacg acguggagaa cgaggagaag gugaagcugg      660

gcaugaccaa cagccacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  3012
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt4)

<400>  3012
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ugaccaagcu gcugcccgcc cugcugcugc agcacgugcu gcugcaccug cugcugcugc      120

ccaucgccau ccccuacgcc gagggccaga gaaagagaag aaacaccauc cacgaguuca      180

agaagagcgc caagaccacc cugaucaaga ucgaccccgc ccugaagauc aagaccaaga      240

aggugaacac cgccgaccag ugcgccaaca gaugcaccag aaacaagggc cugcccuuca      300

ccugcaaggc cuucguguuc gacaaggcca gaaagcagug ccugugguuc cccuucaaca      360

gcaugagcag cggcgugaag aaggaguucg gccacgaguu cgaccuguac gagaacaagg      420

acuacaucag aaacugcauc aucggcaagg gcagaagcua caagggcacc gugagcauca      480

ccaagagcgg caucaagugc cagcccugga gcagcaugau cccccacgag cacagcuucc      540

ugcccagcag cuacagaggc aaggaccugc aggagaacua cugcagaaac cccagaggcg      600

aggagggcgg ccccuggugc uucaccagca accccgaggu gagauacgag gugugcgaca      660

ucccccagug cagcgaggug gagugcauga ccugcaacgg cgagagcuac agaggccuga      720

uggaccacac cgagagcggc aagaucugcc agagauggga ccaccagacc ccccacagac      780

acaaguuccu gcccgagaga uaccccgaca agggcuucga cgacaacuac ugcagaaacc      840

ccgacggcca gcccagaccc uggugcuaca cccuggaccc ccacaccaga ugggaguacu      900

gcgccaucaa gaccugcgcc gacaacacca ugaacgacac cgacgugccc cuggagacca      960

ccgagugcau ccagggccag ggcgagggcu acagaggcac cgugaacacc aucuggaacg     1020

gcauccccug ccagagaugg gacagccagu acccccacga gcacgacaug acccccgaga     1080

acuucaagug caaggaccug agagagaacu acugcagaaa ccccgacggc agcgagagcc     1140

ccuggugcuu caccaccgac cccaacauca gagugggcua cugcagccag auccccaacu     1200

gcgacaugag ccacggccag gacugcuaca gaggcaacgg caagaacuac augggcaacc     1260

ugagccagac cagaagcggc cugaccugca gcauguggga caagaacaug gaggaccugc     1320

acagacacau cuucugggag cccgacgcca gcaagcugaa cgagaacuac ugcagaaacc     1380

ccgacgacga cgcccacggc cccuggugcu acaccggcaa cccccugauc cccugggacu     1440

acugccccau cagcagaugc gagggcgaca ccacccccac caucgugaac cuggaccacc     1500

ccgugaucag cugcgccaag accaagcagc ugagaguggu gaacggcauc cccaccagaa     1560

ccaacaucgg cuggauggug agccugagau acagaaacaa gcacaucugc ggcggcagcc     1620

ugaucaagga gagcugggug cugaccgcca gacagugcuu ccccagcaga gaccugaagg     1680

acuacgaggc cuggcugggc auccacgacg ugcacggcag aggcgacgag aagugcaagc     1740

aggugcugaa cgugagccag cugguguacg gccccgaggg cagcgaccug gugcugauga     1800

agcuggccag acccgccgug cuggacgacu ucgugagcac caucgaccug cccaacuacg     1860

gcugcaccau ccccgagaag accagcugca gcguguacgg cuggggcuac accggccuga     1920

ucaacuacga cggccugcug agaguggccc accuguacau caugggcaac gagaagugca     1980

gccagcacca cagaggcaag gugacccuga acgagagcga gaucugcgcc ggcgccgaga     2040

agaucggcag cggccccugc gagggcgacu acggcggccc ccuggugugc gagcagcaca     2100

agaugagaau ggugcugggc gugaucgugc ccggcagagg cugcgccauc cccaacagac     2160

ccggcaucuu cgugagagug gccuacuacg ccaaguggau ccacaagauc auccugaccu     2220

acaaggugcc ccagagcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  3013
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt4)

<400>  3013
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aggccgccgc caucggcauc gaccugggca ccaccuacag cugcgugggc guguuccagc      120

acggcaaggu ggagaucauc gccaacgacc agggcaacag aaccaccccc agcuacgugg      180

ccuucaccga caccgagaga cugaucggcg acgccgccaa gaaccaggug gcccugaacc      240

cccagaacac cguguucgac gccaagagac ugaucggcag aaaguucggc gaccccgugg      300

ugcagagcga caugaagcac uggcccuucc aggugaucaa cgacggcgac aagcccaagg      360

ugcaggugag cuacaagggc gagaccaagg ccuucuaccc cgaggagauc agcagcaugg      420

ugcugaccaa gaugaaggag aucgccgagg ccuaccuggg cuaccccgug accaacgccg      480

ugaucaccgu gcccgccuac uucaacgaca gccagagaca ggccaccaag gacgccggcg      540

ugaucgccgg ccugaacgug cugagaauca ucaacgagcc caccgccgcc gccaucgccu      600

acggccugga cagaaccggc aagggcgaga gaaacgugcu gaucuucgac cugggcggcg      660

gcaccuucga cgugagcauc cugaccaucg acgacggcau cuucgaggug aaggccaccg      720

ccggcgacac ccaccugggc ggcgaggacu ucgacaacag acuggugaac cacuucgugg      780

aggaguucaa gagaaagcac aagaaggaca ucagccagaa caagagagcc gugagaagac      840

ugagaaccgc cugcgagaga gccaagagaa cccugagcag cagcacccag gccagccugg      900

agaucgacag ccuguucgag ggcaucgacu ucuacaccag caucaccaga gccagauucg      960

aggagcugug cagcgaccug uucagaagca cccuggagcc cguggagaag gcccugagag     1020

acgccaagcu ggacaaggcc cagauccacg accuggugcu ggugggcggc agcaccagaa     1080

uccccaaggu gcagaagcug cugcaggacu ucuucaacgg cagagaccug aacaagagca     1140

ucaaccccga cgaggccgug gccuacggcg ccgccgugca ggccgccauc cugaugggcg     1200

acaagagcga gaacgugcag gaccugcugc ugcuggacgu ggccccccug agccugggcc     1260

uggagaccgc cggcggcgug augaccgccc ugaucaagag aaacagcacc auccccacca     1320

agcagaccca gaucuucacc accuacagcg acaaccagcc cggcgugcug auccaggugu     1380

acgagggcga gagagccaug accaaggaca acaaccugcu gggcagauuc gagcugagcg     1440

gcaucccccc cgcccccaga ggcgugcccc agaucgaggu gaccuucgac aucgacgcca     1500

acggcauccu gaacgugacc gccaccgaca agagcaccgg caaggccaac aagaucacca     1560

ucaccaacga caagggcaga cugagcaagg aggagaucga gagaauggug caggaggccg     1620

agaaguacaa ggccgaggac gaggugcaga gagagagagu gagcgccaag aacgcccugg     1680

agagcuacgc cuucaacaug aagagcgccg uggaggacga gggccugaag ggcaagauca     1740

gcgaggccga caagaagaag gugcuggaca agugccagga ggugaucagc uggcuggacg     1800

ccaacacccu ggccgagaag gacgaguucg agcacaagag aaaggagcug gagcaggugu     1860

gcaaccccau caucagcggc cuguaccagg gcgccggcgg ccccggcccc ggcggcuucg     1920

gcgcccaggg ccccaagggc ggcagcggca gcggccccac caucgaggag guggacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3014
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt4)

<400>  3014
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aggccgccgc caucggcauc gaccugggca ccaccuacag cugcgugggc guguuccagc      120

acggcaaggu ggagaucauc gccaacgacc agggcaacag aaccaccccc agcuacgugg      180

ccuucaccga caccgagaga cugaucggcg acgccgccaa gaaccaggug gcccugaacc      240

cccagaacac cguguucgac gccaagagac ugaucggcag aaaguucggc gaccccgugg      300

ugcagagcga caugaagcac uggcccuucc aggugaucaa cgacggcgac aagcccaagg      360

ugcaggugag cuacaagggc gagaccaagg ccuucuaccc cgaggagauc agcagcaugg      420

ugcugaccaa gaugaaggag aucgccgagg ccuaccuggg cuaccccgug accaacgccg      480

ugaucaccgu gcccgccuac uucaacgaca gccagagaca ggccaccaag gacgccggcg      540

ugaucgccgg ccugaacgug cugagaauca ucaacgagcc caccgccgcc gccaucgccu      600

acggccugga cagaaccggc aagggcgaga gaaacgugcu gaucuucgac cugggcggcg      660

gcaccuucga cgugagcauc cugaccaucg acgacggcau cuucgaggug aaggccaccg      720

ccggcgacac ccaccugggc ggcgaggacu ucgacaacag acuggugaac cacuucgugg      780

aggaguucaa gagaaagcac aagaaggaca ucagccagaa caagagagcc gugagaagac      840

ugagaaccgc cugcgagaga gccaagagaa cccugagcag cagcacccag gccagccugg      900

agaucgacag ccuguucgag ggcaucgacu ucuacaccag caucaccaga gccagauucg      960

aggagcugug cagcgaccug uucagaagca cccuggagcc cguggagaag gcccugagag     1020

acgccaagcu ggacaaggcc cagauccacg accuggugcu ggugggcggc agcaccagaa     1080

uccccaaggu gcagaagcug cugcaggacu ucuucaacgg cagagaccug aacaagagca     1140

ucaaccccga cgaggccgug gccuacggcg ccgccgugca ggccgccauc cugaugggcg     1200

acaagagcga gaacgugcag gaccugcugc ugcuggacgu ggccccccug agccugggcc     1260

uggagaccgc cggcggcgug augaccgccc ugaucaagag aaacagcacc auccccacca     1320

agcagaccca gaucuucacc accuacagcg acaaccagcc cggcgugcug auccaggugu     1380

acgagggcga gagagccaug accaaggaca acaaccugcu gggcagauuc gagcugagcg     1440

gcaucccccc cgcccccaga ggcgugcccc agaucgaggu gaccuucgac aucgacgcca     1500

acggcauccu gaacgugacc gccaccgaca agagcaccgg caaggccaac aagaucacca     1560

ucaccaacga caagggcaga cugagcaagg aggagaucga gagaauggug caggaggccg     1620

agaaguacaa ggccgaggac gaggugcaga gagagagagu gagcgccaag aacgcccugg     1680

agagcuacgc cuucaacaug aagagcgccg uggaggacga gggccugaag ggcaagauca     1740

gcgaggccga caagaagaag gugcuggaca agugccagga ggugaucagc uggcuggacg     1800

ccaacacccu ggccgagaag gacgaguucg agcacaagag aaaggagcug gagcaggugu     1860

gcaaccccau caucagcggc cuguaccagg gcgccggcgg ccccggcccc ggcggcuucg     1920

gcgcccaggg ccccaagggc ggcagcggca gcggccccac caucgaggag guggacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3015
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt4)

<400>  3015
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

ccgccaaggg caucgccauc ggcaucgacc ugggcaccac cuacagcugc gugggcgugu      120

uccagcacgg caagguggag aucaucgcca acgaccaggg caacagaacc acccccagcu      180

acguggccuu caccgacacc gagagacuga ucggcgacgc cgccaagaac cagguggcca      240

ugaaccccca gaacaccgug uucgacgcca agagacugau cggcagaaag uucaacgacc      300

ccguggugca ggccgacaug aagcuguggc ccuuccaggu gaucaacgag ggcggcaagc      360

ccaaggugcu ggugagcuac aagggcgaga acaaggccuu cuaccccgag gagaucagca      420

gcauggugcu gaccaagcug aaggagaccg ccgaggccuu ccugggccac cccgugacca      480

acgccgugau caccgugccc gccuacuuca acgacagcca gagacaggcc accaaggacg      540

ccggcgugau cgccggccug aacgugcuga gaaucaucaa cgagcccacc gccgccgcca      600

ucgccuacgg ccuggacaag ggcggccagg gcgagagaca cgugcugauc uucgaccugg      660

gcggcggcac cuucgacgug agcauccuga ccaucgacga cggcaucuuc gaggugaagg      720

ccaccgccgg cgacacccac cugggcggcg aggacuucga caacagacug gugagccacu      780

ucguggagga guucaagaga aagcacaaga aggacaucag ccagaacaag agagccguga      840

gaagacugag aaccgccugc gagagagcca agagaacccu gagcagcagc acccaggcca      900

accuggagau cgacagccug uacgagggca ucgacuucua caccagcauc accagagcca      960

gauucgagga gcugugcgcc gaccuguuca gaggcacccu ggagcccgug gagaaggccc     1020

ugagagacgc caagauggac aaggccaaga uccacgacau cgugcuggug ggcggcagca     1080

ccagaauccc caaggugcag agacugcugc aggacuacuu caacggcaga gaccugaaca     1140

agagcaucaa ccccgacgag gccguggccu acggcgccgc cgugcaggcc gccauccuga     1200

ugggcgacaa gagcgagaag gugcaggacc ugcugcugcu ggacguggcc ccccugagcc     1260

ugggccugga gaccgccggc ggcgugauga ccgcccugau caagagaaac agcaccaucc     1320

ccaccaagca gacccagauc uucaccaccu acagcgacaa ccagcccggc gugcugaucc     1380

agguguacga gggcgagaga gccaugacca aggacaacaa ccugcugggc agauucgacc     1440

ugaccggcau cccccccgcc cccagaggcg ugccccagau cgaggugacc uucgacaucg     1500

acgccaacgg cauccugaac gugaccgcca ccgacaagag caccggcaag gugaacaaga     1560

ucaccaucac caacgacaag ggcagacuga gcaaggagga gaucgagaga auggugcugg     1620

acgccgagaa guacaaggcc gaggacgagg ugcagagaga gaagaucgcc gccaagaacg     1680

cccuggagag cuacgccuuc aacaugaaga gcguggugag cgacgagggc cugaagggca     1740

agaucagcga gagcgacaag aacaagaucc uggacaagug caacgagcug cugagcuggc     1800

uggaggugaa ccagcuggcc gagaaggacg aguucgacca caagagaaag gagcuggagc     1860

agaugugcaa ccccaucauc accaagcugu accagggcgg cugcaccggc cccgccugcg     1920

gcaccggcua cgugcccggc agacccgcca ccggccccac caucgaggag guggacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3016
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt4)

<400>  3016
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

ccagaggccc cgccaucggc aucgaccugg gcaccaccua cagcugcgug ggcguguucc      120

agcacggcaa gguggagauc aucgccaacg accagggcaa cagaaccacc cccagcuacg      180

uggccuucac cgacaccgag agacugaucg gcgacgccgc caagaaccag guggccauga      240

accccaccaa caccaucuuc gacgccaaga gacugaucgg cagaaaguuc gaggacgcca      300

ccgugcagag cgacaugaag cacuggcccu ucagaguggu gagcgagggc ggcaagccca      360

aggugcaggu ggaguacaag ggcgagacca agaccuucuu ccccgaggag aucagcagca      420

uggugcugac caagaugaag gagaucgccg aggccuaccu gggcggcaag gugcacagcg      480

ccgugaucac cgugcccgcc uacuucaacg acagccagag acaggccacc aaggacgccg      540

gcaccaucac cggccugaac gugcugagaa ucaucaacga gcccaccgcc gccgccaucg      600

ccuacggccu ggacaagaag ggcugcgccg gcggcgagaa gaacgugcug aucuucgacc      660

ugggcggcgg caccuucgac gugagcaucc ugaccaucga ggacggcauc uucgagguga      720

agagcaccgc cggcgacacc caccugggcg gcgaggacuu cgacaacaga auggugagcc      780

accuggccga ggaguucaag agaaagcaca agaaggacau cggccccaac aagagagccg      840

ugagaagacu gagaaccgcc ugcgagagag ccaagagaac ccugagcagc agcacccagg      900

ccagcaucga gaucgacagc cuguacgagg gcguggacuu cuacaccagc aucaccagag      960

ccagauucga ggagcugaac gccgaccugu ucagaggcac ccuggagccc guggagaagg     1020

cccugagaga cgccaagcug gacaagggcc agauccagga gaucgugcug gugggcggca     1080

gcaccagaau ccccaagauc cagaagcugc ugcaggacuu cuucaacggc aaggagcuga     1140

acaagagcau caaccccgac gaggccgugg ccuacggcgc cgccgugcag gccgccaucc     1200

ugaucggcga caagagcgag aacgugcagg accugcugcu gcuggacgug accccccuga     1260

gccugggcau cgagaccgcc ggcggcguga ugaccccccu gaucaagaga aacaccacca     1320

uccccaccaa gcagacccag accuucacca ccuacagcga caaccagagc agcgugcugg     1380

ugcaggugua cgagggcgag agagccauga ccaaggacaa caaccugcug ggcaaguucg     1440

accugaccgg cauccccccc gcccccagag gcgugcccca gaucgaggug accuucgaca     1500

ucgacgccaa cggcauccug aacgugaccg ccgccgacaa gagcaccggc aaggagaaca     1560

agaucaccau caccaacgac aagggcagac ugagcaagga cgacaucgac agaauggugc     1620

aggaggccga gagauacaag agcgaggacg aggccaacag agacagagug gccgccaaga     1680

acgcccugga gagcuacacc uacaacauca agcagaccgu ggaggacgag aagcugagag     1740

gcaagaucag cgagcaggac aagaacaaga uccuggacaa gugccaggag gugaucaacu     1800

ggcuggacag aaaccagaug gccgagaagg acgaguacga gcacaagcag aaggagcugg     1860

agagagugug caaccccauc aucagcaagc uguaccaggg cggccccggc ggcggcagcg     1920

gcggcggcgg cagcggcgcc agcggcggcc ccaccaucga ggagguggac ugaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  3017
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt4)

<400>  3017
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggugggcau cgaccugggc uuccagagcu gcuacguggc cguggccaga gccggcggca      120

ucgagaccau cgccaacgag uacagcgaca gaugcacccc cgccugcauc agcuucggcc      180

ccaagaacag aagcaucggc gccgccgcca agagccaggu gaucagcaac gccaagaaca      240

ccgugcaggg cuucaagaga uuccacggca gagccuucag cgaccccuuc guggaggccg      300

agaagagcaa ccuggccuac gacaucgugc agcugcccac cggccugacc ggcaucaagg      360

ugaccuacau ggaggaggag agaaacuuca ccaccgagca ggugaccgcc augcugcuga      420

gcaagcugaa ggagaccgcc gagagcgugc ugaagaagcc cgugguggac ugcgugguga      480

gcgugcccug cuucuacacc gacgccgaga gaagaagcgu gauggacgcc acccagaucg      540

ccggccugaa cugccugaga cugaugaacg agaccaccgc cguggcccug gccuacggca      600

ucuacaagca ggaccugccc gcccuggagg agaagcccag aaacguggug uucguggaca      660

ugggccacag cgccuaccag gugagcgugu gcgccuucaa cagaggcaag cugaaggugc      720

uggccaccgc cuucgacacc acccugggcg gcagaaaguu cgacgaggug cuggugaacc      780

acuucugcga ggaguucggc aagaaguaca agcuggacau caagagcaag aucagagccc      840

ugcugagacu gagccaggag ugcgagaagc ugaagaagcu gaugagcgcc aacgccagcg      900

accugccccu gagcaucgag ugcuucauga acgacgugga cgugagcggc accaugaaca      960

gaggcaaguu ccuggagaug ugcaacgacc ugcuggccag aguggagccc ccccugagaa     1020

gcgugcugga gcagaccaag cugaagaagg aggacaucua cgccguggag aucgugggcg     1080

gcgccaccag aauccccgcc gugaaggaga agaucagcaa guucuucggc aaggagcuga     1140

gcaccacccu gaacgccgac gaggccguga ccagaggcug cgcccugcag ugcgccaucc     1200

ugagccccgc cuucaaggug agagaguuca gcaucaccga cguggugccc uaccccauca     1260

gccugagaug gaacagcccc gccgaggagg gcagcagcga cugcgaggug uucagcaaga     1320

accacgccgc ccccuucagc aaggugcuga ccuucuacag aaaggagccc uucacccugg     1380

aggccuacua cagcagcccc caggaccugc ccuaccccga ccccgccauc gcccaguuca     1440

gcgugcagaa ggugaccccc cagagcgacg gcagcagcag caaggugaag gugaagguga     1500

gagugaacgu gcacggcauc uucagcguga gcagcgccag ccugguggag gugcacaaga     1560

gcgaggagaa cgaggagccc auggagaccg accagaacgc caaggaggag gagaagaugc     1620

agguggacca ggaggagccc cacguggagg agcagcagca gcagaccccc gccgagaaca     1680

aggccgagag cgaggagaug gagaccagcc aggccggcag caaggacaag aagauggacc     1740

agccccccca ggccaagaag gccaagguga agaccagcac cguggaccug cccaucgaga     1800

accagcugcu guggcagauc gacagagaga ugcugaaccu guacaucgag aacgagggca     1860

agaugaucau gcaggacaag cuggagaagg agagaaacga cgccaagaac gccguggagg     1920

aguacgugua cgagaugaga gacaagcuga gcggcgagua cgagaaguuc gugagcgagg     1980

acgacagaaa cagcuucacc cugaagcugg aggacaccga gaacuggcug uacgaggacg     2040

gcgaggacca gcccaagcag guguacgugg acaagcuggc cgagcugaag aaccugggcc     2100

agcccaucaa gaucagauuc caggagagcg aggagagacc caagcuguuc gaggagcugg     2160

gcaagcagau ccagcaguac augaagauca ucagcagcuu caagaacaag gaggaccagu     2220

acgaccaccu ggacgccgcc gacaugacca agguggagaa gagcaccaac gaggccaugg     2280

aguggaugaa caacaagcug aaccugcaga acaagcagag ccugaccaug gaccccgugg     2340

ugaagagcaa ggagaucgag gccaagauca aggagcugac cagcaccugc agccccauca     2400

ucagcaagcc caagcccaag guggagcccc ccaaggagga gcagaagaac gccgagcaga     2460

acggccccgu ggacggccag ggcgacaacc ccggccccca ggccgccgag cagggcaccg     2520

acaccgccgu gcccagcgac agcgacaaga agcugcccga gauggacauc gacugaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  3018
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt4)

<400>  3018
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggugggcau cgaccugggc uuccugaacu gcuacaucgc cguggccaga agcggcggca      120

ucgagaccau cgccaacgag uacagcgaca gaugcacccc cgccugcauc agccugggca      180

gcagaaccag agccaucggc aacgccgcca agagccagau cgugaccaac gugagaaaca      240

ccauccacgg cuucaagaag cugcacggca gaagcuucga cgaccccauc gugcagaccg      300

agagaaucag acugcccuac gagcugcaga agaugcccaa cggcagcgcc ggcgugaagg      360

ugagauaccu ggaggaggag agacccuucg ccaucgagca ggugaccggc augcugcugg      420

ccaagcugaa ggagaccagc gagaacgccc ugaagaagcc cguggccgac ugcgugauca      480

gcauccccag cuucuucacc gacgccgaga gaagaagcgu gauggccgcc gcccaggugg      540

ccggccugaa cugccugaga cugaugaacg agaccaccgc cguggcccug gccuacggca      600

ucuacaagca ggaccugccc ccccuggacg agaagcccag aaacguggug uucaucgaca      660

ugggccacag cgccuaccag gugcuggugu gcgccuucaa caagggcaag cugaaggugc      720

uggccaccac cuucgacccc uaccugggcg gcagaaacuu cgacgaggcc cugguggacu      780

acuucugcga cgaguucaag accaaguaca agaucaacgu gaaggagaac agcagagccc      840

ugcugagacu guaccaggag ugcgagaagc ugaagaagcu gaugagcgcc aacgccagcg      900

accugccccu gaacaucgag ugcuucauga acgaccugga cgugagcagc aagaugaaca      960

gagcccaguu cgagcagcug ugcgccagcc ugcuggccag aguggagccc ccccugaagg     1020

ccgugaugga gcaggccaac cugcagagag aggacaucag cagcaucgag aucgugggcg     1080

gcgccaccag aauccccgcc gugaaggagc agaucaccaa guucuuccug aaggacauca     1140

gcaccacccu gaacgccgac gaggccgugg ccagaggcug cgcccugcag ugcgccaucc     1200

ugagccccgc cuucaaggug agagaguuca gcaucaccga ccuggugccc uacagcauca     1260

cccugagaug gaagaccagc uucgaggacg gcagcggcga gugcgaggug uucugcaaga     1320

accaccccgc ccccuucagc aaggugauca ccuuccacaa gaaggagccc uucgagcugg     1380

aggccuucua caccaaccug cacgaggugc ccuaccccga cgccagaauc ggcagcuuca     1440

ccauccagaa cguguucccc cagagcgacg gcgacagcag caaggugaag gugaagguga     1500

gagugaacau ccacggcauc uucagcgugg ccagcgccag cgugaucgag aagcagaacc     1560

uggagggcga ccacagcgac gcccccaugg agaccgagac cagcuucaag aacgagaaca     1620

aggacaacau ggacaagaug cagguggacc aggaggaggg ccaccagaag ugccacgccg     1680

agcacacccc cgaggaggag aucgaccaca ccggcgccaa gaccaagagc gccgugagcg     1740

acaagcagga cagacugaac cagacccuga agaagggcaa ggugaagagc aucgaccugc     1800

ccauccagag cagccugugc agacagcugg gccaggaccu gcugaacagc uacaucgaga     1860

acgagggcaa gaugaucaug caggacaagc uggagaagga gagaaacgac gccaagaacg     1920

ccguggagga guacguguac gacuucagag acagacuggg caccguguac gagaaguuca     1980

ucacccccga ggaccugagc aagcugagcg ccgugcugga ggacaccgag aacuggcugu     2040

acgaggacgg cgaggaccag cccaagcagg uguacgugga caagcugcag gagcugaaga     2100

aguacggcca gcccauccag augaaguaca uggagcacga ggagagaccc aaggcccuga     2160

acgaccuggg caagaagauc cagcugguga ugaaggugau cgaggccuac agaaacaagg     2220

acgagagaua cgaccaccug gaccccaccg agauggagaa gguggagaag ugcaucagcg     2280

acgccaugag cuggcugaac agcaagauga acgcccagaa caagcugagc cugacccagg     2340

accccguggu gaaggugagc gagaucgugg ccaagagcaa ggagcuggac aacuucugca     2400

accccaucau cuacaagccc aagcccaagg ccgaggugcc cgaggacaag cccaaggcca     2460

acagcgagca caacggcccc auggacggcc agagcggcac cgagaccaag agcgacagca     2520

ccaaggacag cagccagcac accaagagca gcggcgagau ggagguggac ugaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  3019
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt4)

<400>  3019
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ugagccuggu ggccgccaug cugcugcugc ugagcgccgc cagagccgag gaggaggaca      120

agaaggagga cgugggcacc guggugggca ucgaccuggg caccaccuac agcugcgugg      180

gcguguucaa gaacggcaga guggagauca ucgccaacga ccagggcaac agaaucaccc      240

ccagcuacgu ggccuucacc cccgagggcg agagacugau cggcgacgcc gccaagaacc      300

agcugaccag caaccccgag aacaccgugu ucgacgccaa gagacugauc ggcagaaccu      360

ggaacgaccc cagcgugcag caggacauca aguuccugcc cuucaaggug guggagaaga      420

agaccaagcc cuacauccag guggacaucg gcggcggcca gaccaagacc uucgcccccg      480

aggagaucag cgccauggug cugaccaaga ugaaggagac cgccgaggcc uaccugggca      540

agaaggugac ccacgccgug gugaccgugc ccgccuacuu caacgacgcc cagagacagg      600

ccaccaagga cgccggcacc aucgccggcc ugaacgugau gagaaucauc aacgagccca      660

ccgccgccgc caucgccuac ggccuggaca agagagaggg cgagaagaac auccuggugu      720

ucgaccuggg cggcggcacc uucgacguga gccugcugac caucgacaac ggcguguucg      780

aggugguggc caccaacggc gacacccacc ugggcggcga ggacuucgac cagagaguga      840

uggagcacuu caucaagcug uacaagaaga agaccggcaa ggacgugaga aaggacaaca      900

gagccgugca gaagcugaga agagaggugg agaaggccaa gagagcccug agcagccagc      960

accaggccag aaucgagauc gagagcuucu acgagggcga ggacuucagc gagacccuga     1020

ccagagccaa guucgaggag cugaacaugg accuguucag aagcaccaug aagcccgugc     1080

agaaggugcu ggaggacagc gaccugaaga agagcgacau cgacgagauc gugcuggugg     1140

gcggcagcac cagaaucccc aagauccagc agcuggugaa ggaguucuuc aacggcaagg     1200

agcccagcag aggcaucaac cccgacgagg ccguggccua cggcgccgcc gugcaggccg     1260

gcgugcugag cggcgaccag gacaccggcg accuggugcu gcuggacgug ugcccccuga     1320

cccugggcau cgagaccgug ggcggcguga ugaccaagcu gauccccaga aacaccgugg     1380

ugcccaccaa gaagagccag aucuucagca ccgccagcga caaccagccc accgugacca     1440

ucaaggugua cgagggcgag agaccccuga ccaaggacaa ccaccugcug ggcaccuucg     1500

accugaccgg cauccccccc gcccccagag gcgugcccca gaucgaggug accuucgaga     1560

ucgacgugaa cggcauccug agagugaccg ccgaggacaa gggcaccggc aacaagaaca     1620

agaucaccau caccaacgac cagaacagac ugacccccga ggagaucgag agaaugguga     1680

acgacgccga gaaguucgcc gaggaggaca agaagcugaa ggagagaauc gacaccagaa     1740

acgagcugga gagcuacgcc uacagccuga agaaccagau cggcgacaag gagaagcugg     1800

gcggcaagcu gagcagcgag gacaaggaga ccauggagaa ggccguggag gagaagaucg     1860

aguggcugga gagccaccag gacgccgaca ucgaggacuu caaggccaag aagaaggagc     1920

uggaggagau cgugcagccc aucaucagca agcuguacgg cagcgccggc ccccccccca     1980

ccggcgagga ggacaccgcc gagaaggacg agcugugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  3020
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt4)

<400>  3020
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

cccccagaga gcuggccgug ggcaucgacc ugggcaccac cuacagcugc gugggcgugu      120

uccagcaggg cagaguggag auccuggcca acgaccaggg caacagaacc acccccagcu      180

acguggccuu caccgacacc gagagacugg ugggcgacgc cgccaagagc caggccgccc      240

ugaaccccca caacaccgug uucgacgcca agagacugau cggcagaaag uucgccgaca      300

ccaccgugca gagcgacaug aagcacuggc ccuucagagu ggugagcgag ggcggcaagc      360

ccaaggugag agugugcuac agaggcgagg acaagaccuu cuaccccgag gagaucagca      420

gcauggugcu gagcaagaug aaggagaccg ccgaggccua ccugggccag cccgugaagc      480

acgccgugau caccgugccc gccuacuuca acgacagcca gagacaggcc accaaggacg      540

ccggcgccau cgccggccug aacgugcuga gaaucaucaa cgagcccacc gccgccgcca      600

ucgccuacgg ccuggacaga agaggcgccg gcgagagaaa cgugcugauc uucgaccugg      660

gcggcggcac cuucgacgug agcgugcuga gcaucgacgc cggcguguuc gaggugaagg      720

ccaccgccgg cgacacccac cugggcggcg aggacuucga caacagacug gugaaccacu      780

ucauggagga guucagaaga aagcacggca aggaccugag cggcaacaag agagcccuga      840

gaagacugag aaccgccugc gagagagcca agagaacccu gagcagcagc acccaggcca      900

cccuggagau cgacagccug uucgagggcg uggacuucua caccagcauc accagagcca      960

gauucgagga gcugugcagc gaccuguuca gaagcacccu ggagcccgug gagaaggccc     1020

ugagagacgc caagcuggac aaggcccaga uccacgacgu ggugcuggug ggcggcagca     1080

ccagaauccc caaggugcag aagcugcugc aggacuucuu caacggcaag gagcugaaca     1140

agagcaucaa ccccgacgag gccguggccu acggcgccgc cgugcaggcc gccgugcuga     1200

ugggcgacaa gugcgagaag gugcaggacc ugcugcugcu ggacguggcc ccccugagcc     1260

ugggccugga gaccgccggc ggcgugauga ccacccugau ccagagaaac gccaccaucc     1320

ccaccaagca gacccagacc uucaccaccu acagcgacaa ccagcccggc guguucaucc     1380

agguguacga gggcgagaga gccaugacca aggacaacaa ccugcugggc agauucgagc     1440

ugagcggcau cccccccgcc cccagaggcg ugccccagau cgaggugacc uucgacaucg     1500

acgccaacgg cauccugagc gugaccgcca ccgacagaag caccggcaag gccaacaaga     1560

ucaccaucac caacgacaag ggcagacuga gcaaggagga gguggagaga auggugcacg     1620

aggccgagca guacaaggcc gaggacgagg cccagagaga cagaguggcc gccaagaaca     1680

gccuggaggc ccacguguuc cacgugaagg gcagccugca ggaggagagc cugagagaca     1740

agauccccga ggaggacaga agaaagaugc aggacaagug cagagaggug cuggccuggc     1800

uggagcacaa ccagcuggcc gagaaggagg aguacgagca ccagaagaga gagcuggagc     1860

agaucugcag acccaucuuc agcagacugu acggcggccc cggcgugccc ggcggcagca     1920

gcugcggcac ccaggccaga cagggcgacc ccagcaccgg ccccaucauc gaggaggugg     1980

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  3021
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt4)

<400>  3021
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

cccccagaga gcuggccgug ggcaucgacc ugggcaccac cuacagcugc gugggcgugu      120

uccagcaggg cagaguggag auccuggcca acgaccaggg caacagaacc acccccagcu      180

acguggccuu caccgacacc gagagacugg ugggcgacgc cgccaagagc caggccgccc      240

ugaaccccca caacaccgug uucgacgcca agagacugau cggcagaaag uucgccgaca      300

ccaccgugca gagcgacaug aagcacuggc ccuuccaggu ggugagcgag ggcggcaagc      360

ccaaggugag agugugcuac agaggcgagg acaagaccuu cuaccccgag gagaucagca      420

gcauggugcu gagcaagaug aaggagaccg ccgaggccua ccugggccag cccgugaagc      480

acgccgugau caccgugccc accuacuuca gcaacagcca gagacaggcc accaaggacg      540

ccggcgccau cgccggccug aaggugcugc ccaucaucaa cgaggccacc gccgccgcca      600

ucgccuacgg ccuggacaga agaggcgccg gcaagagaaa cgugcugauc uucgaccugg      660

gcggcggcac cuucgacgug agcgugcuga gcaucgacgc cggcguguuc gaggugaagg      720

ccaccgccgg cgacacccac cugggcggcg aggacuucga caacagacug gugaaccacu      780

ucauggagga guucagaaga aagcacggca aggaccugag cggcaacaag agagcccuga      840

gaagacugag aaccgccugc gagagagcca agagaacccc cagcagcagc acccaggcca      900

cccuggagau cgacagccug uucgagggcg uggacuucua caagagcauc accagagcca      960

gauucgagga gcugugcagc gaccuguuca gaagcacccu ggagcccgug gagaaggccc     1020

ugagagacgc caagcuggac aaggcccaga uccacgacuu cgugcugggc ggcggccugc     1080

acagccaccc ccagggcgcc gagguggccg ccggccugcu gcagagacag ggcgccgagc     1140

aggagcacca gcccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  3022
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt4)

<400>  3022
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagca       60

agggccccgc cgugggcauc gaccugggca ccaccuacag cugcgugggc guguuccagc      120

acggcaaggu ggagaucauc gccaacgacc agggcaacag aaccaccccc agcuacgugg      180

ccuucaccga caccgagaga cugaucggcg acgccgccaa gaaccaggug gccaugaacc      240

ccaccaacac cguguucgac gccaagagac ugaucggcag aagauucgac gacgccgugg      300

ugcagagcga caugaagcac uggcccuuca ugguggugaa cgacgccggc agacccaagg      360

ugcaggugga guacaagggc gagaccaaga gcuucuaccc cgaggaggug agcagcaugg      420

ugcugaccaa gaugaaggag aucgccgagg ccuaccuggg caagaccgug accaacgccg      480

uggugaccgu gcccgccuac uucaacgaca gccagagaca ggccaccaag gacgccggca      540

ccaucgccgg ccugaacgug cugagaauca ucaacgagcc caccgccgcc gccaucgccu      600

acggccugga caagaaggug ggcgccgaga gaaacgugcu gaucuucgac cugggcggcg      660

gcaccuucga cgugagcauc cugaccaucg aggacggcau cuucgaggug aagagcaccg      720

ccggcgacac ccaccugggc ggcgaggacu ucgacaacag aauggugaac cacuucaucg      780

ccgaguucaa gagaaagcac aagaaggaca ucagcgagaa caagagagcc gugagaagac      840

ugagaaccgc cugcgagaga gccaagagaa cccugagcag cagcacccag gccagcaucg      900

agaucgacag ccuguacgag ggcaucgacu ucuacaccag caucaccaga gccagauucg      960

aggagcugaa cgccgaccug uucagaggca cccuggaccc cguggagaag gcccugagag     1020

acgccaagcu ggacaagagc cagauccacg acaucgugcu ggugggcggc agcaccagaa     1080

uccccaagau ccagaagcug cugcaggacu ucuucaacgg caaggagcug aacaagagca     1140

ucaaccccga cgaggccgug gccuacggcg ccgccgugca ggccgccauc cugagcggcg     1200

acaagagcga gaacgugcag gaccugcugc ugcuggacgu gaccccccug agccugggca     1260

ucgagaccgc cggcggcgug augaccgugc ugaucaagag aaacaccacc auccccacca     1320

agcagaccca gaccuucacc accuacagcg acaaccagcc cggcgugcug auccaggugu     1380

acgagggcga gagagccaug accaaggaca acaaccugcu gggcaaguuc gagcugaccg     1440

gcaucccccc cgcccccaga ggcgugcccc agaucgaggu gaccuucgac aucgacgcca     1500

acggcauccu gaacgugagc gccguggaca agagcaccgg caaggagaac aagaucacca     1560

ucaccaacga caagggcaga cugagcaagg aggacaucga gagaauggug caggaggccg     1620

agaaguacaa ggccgaggac gagaagcaga gagacaaggu gagcagcaag aacagccugg     1680

agagcuacgc cuucaacaug aaggccaccg uggaggacga gaagcugcag ggcaagauca     1740

acgacgagga caagcagaag auccuggaca agugcaacga gaucaucaac uggcuggaca     1800

agaaccagac cgccgagaag gaggaguucg agcaccagca gaaggagcug gagaaggugu     1860

gcaaccccau caucaccaag cuguaccaga gcgccggcgg caugcccggc ggcaugcccg     1920

gcggcuuccc cggcggcggc gcccccccca gcggcggcgc cagcagcggc cccaccaucg     1980

aggaggugga cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  3023
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt4)

<400>  3023
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauca       60

gcgccagcag agccgccgcc gccagacugg ugggcgccgc cgccagcaga ggccccaccg      120

ccgccagaca ccaggacagc uggaacggcc ugagccacga ggccuucaga cuggugagca      180

gaagagacua cgccagcgag gccaucaagg gcgccguggu gggcaucgac cugggcacca      240

ccaacagcug cguggccgug auggagggca agcaggccaa ggugcuggag aacgccgagg      300

gcgccagaac cacccccagc gugguggccu ucaccgccga cggcgagaga cuggugggca      360

ugcccgccaa gagacaggcc gugaccaacc ccaacaacac cuucuacgcc accaagagac      420

ugaucggcag aagauacgac gaccccgagg ugcagaagga caucaagaac gugcccuuca      480

agaucgugag agccagcaac ggcgacgccu ggguggaggc ccacggcaag cuguacagcc      540

ccagccagau cggcgccuuc gugcugauga agaugaagga gaccgccgag aacuaccugg      600

gccacaccgc caagaacgcc gugaucaccg ugcccgccua cuucaacgac agccagagac      660

aggccaccaa ggacgccggc cagaucagcg gccugaacgu gcugagagug aucaacgagc      720

ccaccgccgc cgcccuggcc uacggccugg acaagagcga ggacaaggug aucgccgugu      780

acgaccuggg cggcggcacc uucgacauca gcauccugga gauccagaag ggcguguucg      840

aggugaagag caccaacggc gacaccuucc ugggcggcga ggacuucgac caggcccugc      900

ugagacacau cgugaaggag uucaagagag agaccggcgu ggaccugacc aaggacaaca      960

uggcccugca gagagugaga gaggccgccg agaaggccaa gugcgagcug agcagcagcg     1020

ugcagaccga caucaaccug cccuaccuga ccauggacag cagcggcccc aagcaccuga     1080

acaugaagcu gaccagagcc caguucgagg gcaucgugac cgaccugauc agaagaacca     1140

ucgcccccug ccagaaggcc augcaggacg ccgaggugag caagagcgac aucggcgagg     1200

ugauccuggu gggcggcaug accagaaugc ccaaggugca gcagaccgug caggaccugu     1260

ucggcagagc ccccagcaag gccgugaacc ccgacgaggc cguggccauc ggcgccgcca     1320

uccagggcgg cgugcuggcc ggcgacguga ccgacgugcu gcugcuggac gugacccccc     1380

ugagccuggg caucgagacc cugggcggcg uguucaccaa gcugaucaac agaaacacca     1440

ccauccccac caagaagagc cagguguuca gcaccgccgc cgacggccag acccaggugg     1500

agaucaaggu gugccagggc gagagagaga uggccggcga caacaagcug cugggccagu     1560

ucacccugau cggcaucccc cccgccccca gaggcgugcc ccagaucgag gugaccuucg     1620

acaucgacgc caacggcauc gugcacguga gcgccaagga caagggcacc ggcagagagc     1680

agcagaucgu gauccagagc agcggcggcc ugagcaagga cgacaucgag aacaugguga     1740

agaacgccga gaaguacgcc gaggaggaca gaagaaagaa ggagagagug gaggccguga     1800

acauggccga gggcaucauc cacgacaccg agaccaagau ggaggaguuc aaggaccagc     1860

ugcccgccga cgagugcaac aagcugaagg aggagaucag caagaugaga gagcugcugg     1920

ccagaaagga cagcgagacc ggcgagaaca ucagacaggc cgccagcagc cugcagcagg     1980

ccagccugaa gcuguucgag auggccuaca agaagauggc cagcgagaga gagggcagcg     2040

gcagcagcgg caccggcgag cagaaggagg accagaagga ggagaagcag ugaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  3024
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt4)

<400>  3024
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaggaggc cggcggcagc gacggcccca gagagaccgc ccccaccagc gccuacagca      120

gccccgccag aagccugggc gacaccggca ucaccccccu gagccccagc cacaucguga      180

acgacaccga cagcaacgug agcgagcagc agagcuuccu ggugguggug gccguggacu      240

ucggcaccac cagcagcggc uacgccuaca gcuucaccaa ggagcccgag ugcauccacg      300

ugaugagaag augggagggc ggcgaccccg gcgugagcaa ccagaagacc cccaccacca      360

uccugcugac ccccgagaga aaguuccaca gcuucggcua cgccgccaga gacuucuacc      420

acgaccugga ccccaacgag gccaagcagu ggcuguaccu ggagaaguuc aagaugaagc      480

ugcacaccac cggcgaccug accauggaca ccgaccugac cgccgccaac ggcaagaagg      540

ugaaggcccu ggagaucuuc gccuacgccc ugcaguacuu caaggagcag gcccugaagg      600

agcugagcga ccaggccggc agcgaguucg agaacagcga cgugagaugg gugaucaccg      660

ugcccgccau cuggaagcag cccgccaagc aguucaugag acaggccgcc uaccaggccg      720

gccuggccag ccccgagaac agcgagcagc ugaucaucgc ccuggagccc gaggccgcca      780

gcaucuacug cagaaagcug agacugcacc agaugaucga gcugagcagc aaggccgccg      840

ugaacggcua cagcggcagc gacaccgugg gcgccggcuu cacccaggcc aaggagcaca      900

ucagaagaaa cagacagagc agaaccuucc ugguggagaa cgugaucggc gagaucugga      960

gcgagcugga ggagggcgac aaguacgugg ugguggacag cggcggcggc accguggacc     1020

ugaccgugca ccagaucaga cugcccgagg gccaccugaa ggagcuguac aaggccaccg     1080

gcggccccua cggcagccug ggcguggacu acgaguucga gaagcugcug uacaagaucu     1140

ucggcgagga cuucaucgag caguucaaga ucaagagacc cgccgccugg guggaccuga     1200

ugaucgccuu cgagagcaga aagagagccg ccgcccccga cagaaccaac ccccugaaca     1260

ucacccugcc cuucagcuuc aucgacuacu acaagaaguu cagaggccac agcguggagc     1320

acgcccugag aaagagcaac guggacuucg ugaaguggag cagccagggc augcugagaa     1380

ugagccccga cgccaugaac gcccuguuca agcccaccau cgacagcauc aucgagcacc     1440

ugagagaccu guuccagaag cccgagguga gcaccgugaa guuccuguuc cuggugggcg     1500

gcuucgccga ggccccccug cugcagcagg ccgugcaggc cgccuucggc gaccagugca     1560

gaaucaucau cccccaggac gugggccuga ccauccugaa gggcgccgug cuguucggcc     1620

uggaccccgc cgugaucaag gugagaagaa gcccccugac cuacggcgug ggcgugcuga     1680

acagauacgu ggagggcaag cacccccccg agaagcugcu ggugaaggac ggcaccagau     1740

ggugcaccga cguguucgac aaguucauca gcgccgacca gagcguggcc cugggcgagc     1800

uggugaagag aagcuacacc cccgccaagc ccagccagcu ggugaucgug aucaacaucu     1860

acagcagcga gcacgacaac gugagcuuca ucaccgaccc cggcgugaag aagugcggca     1920

cccugagacu ggaccugacc ggcaccagcg gcaccgccgu gcccgccaga agagagaucc     1980

agacccugau gcaguucggc gacaccgaga ucaaggccac cgccaucgac aucgccacca     2040

gcaagagcgu gaaggugggc aucgacuucc ugaacuacug aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  3025
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt4)

<400>  3025
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugg       60

ccgugcccga gaugggccug cagggccugu acaucggcag cagccccgag agaagccccg      120

ugcccagccc ccccggcagc cccagaaccc aggagagcug cggcaucgcc ccccugaccc      180

ccagccagag ccccaagccc gaggugagag ccccccagca ggccagcuuc agcguggugg      240

uggccaucga cuucggcacc accagcagcg gcuacgccuu cagcuucgcc agcgaccccg      300

aggccaucca caugaugaga aagugggagg gcggcgaccc cggcguggcc caccagaaga      360

cccccaccug ccugcugcug acccccgagg gcgccuucca cagcuucggc uacaccgcca      420

gagacuacua ccacgaccug gaccccgagg aggccagaga cuggcuguac uucgagaagu      480

ucaagaugaa gauccacagc gccaccgacc ugacccugaa gacccagcug gaggccguga      540

acggcaagac caugcccgcc cuggaggugu ucgcccacgc ccugagauuc uucagagagc      600

acgcccugca ggagcugaga gagcagagcc ccagccugcc cgagaaggac accgugagau      660

gggugcugac cgugcccgcc aucuggaagc agcccgccaa gcaguucaug agagaggccg      720

ccuaccuggc cggccuggug agcagagaga acgccgagca gcugcugauc gcccuggagc      780

ccgaggccgc cagcguguac ugcagaaagc ugagacugca ccagcugcug gaccugagcg      840

gcagagcccc cggcggcggc agacugggcg agagaagaag caucgacagc agcuucagac      900

aggccagaga gcagcugaga agaagcagac acagcagaac cuuccuggug gagagcggcg      960

ugggcgagcu gugggccgag augcaggccg gcgacagaua cgugguggcc gacugcggcg     1020

gcggcaccgu ggaccugacc gugcaccagc uggagcagcc ccacggcacc cugaaggagc     1080

uguacaaggc cagcggcggc cccuacggcg ccgugggcgu ggaccuggcc uucgagcagc     1140

ugcugugcag aaucuucggc gaggacuuca ucgccaccuu caagagacag agacccgccg     1200

ccugggugga ccugaccauc gccuucgagg ccagaaagag aaccgccggc ccccacagag     1260

ccggcgcccu gaacaucagc cugcccuuca gcuucaucga cuucuacaga aagcagagag     1320

gccacaacgu ggagaccgcc cugagaagaa gcagcgugaa cuucgugaag uggagcagcc     1380

agggcaugcu gagaaugagc ugcgaggcca ugaacgagcu guuccagccc accgugagcg     1440

gcaucaucca gcacaucgag gcccugcugg ccagacccga ggugcagggc gugaagcugc     1500

uguuccuggu gggcggcuuc gccgagagcg ccgugcugca gcacgccgug caggccgccc     1560

ugggcgccag aggccugaga gugguggugc cccacgacgu gggccugacc auccugaagg     1620

gcgccgugcu guucggccag gcccccggcg uggugagagu gagaagaagc ccccugaccu     1680

acggcguggg cgugcugaac agauucgugc ccggcagaca cccccccgag aagcugcugg     1740

ugagagacgg cagaagaugg ugcaccgacg uguucgagag auucguggcc gccgagcaga     1800

gcguggcccu gggcgaggag gugagaagaa gcuacugccc cgccagaccc ggccagagaa     1860

gagugcugau caaccuguac ugcugcgccg ccgaggacgc cagauucauc accgaccccg     1920

gcgugagaaa gugcggcgcc cugagccugg agcuggagcc cgccgacugc ggccaggaca     1980

ccgccggcgc cccccccggc agaagagaga ucagagccgc caugcaguuc ggcgacaccg     2040

agaucaaggu gaccgccgug gacgugagca ccaacagaag cgugagagcc agcaucgacu     2100

uccugagcaa cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  3026
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt4)

<400>  3026
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

gagagaugac cauccugggc agcgccgugc ugacccugcu gcuggccggc uaccuggccc      120

agcaguaccu gccccugccc acccccaagg ugaucggcau cgaccugggc accaccuacu      180

gcagcguggg cguguucuuc cccggcaccg gcaaggugaa ggugaucccc gacgagaacg      240

gccacaucag cauccccagc auggugagcu ucaccgacaa cgacguguac gugggcuacg      300

agagcgugga gcuggccgac agcaaccccc agaacaccau cuacgacgcc aagagauuca      360

ucggcaagau cuucaccgcc gaggagcugg aggccgagau cggcagauac cccuucaagg      420

ugcugaacaa gaacggcaug guggaguuca gcgugaccag caacgagacc aucaccguga      480

gccccgagua cgugggcagc agacugcugc ugaagcugaa ggagauggcc gaggccuacc      540

ugggcaugcc cguggccaac gccgugauca gcgugcccgc cgaguucgac cugaagcaga      600

gaaacagcac caucgaggcc gccaaccugg ccggccugaa gauccugaga gugaucaacg      660

agcccaccgc cgccgccaug gccuacggcc ugcacaaggc cgacguguuc cacgugcugg      720

ugaucgaccu gggcggcggc acccuggacg ugagccugcu gaacaagcag ggcggcaugu      780

uccugaccag agccaugagc ggcaacaaca agcugggcgg ccaggacuuc aaccagagac      840

ugcugcagua ccuguacaag cagaucuacc agaccuacgg cuucgugccc agcagaaagg      900

aggagaucca cagacugaga caggccgugg agauggugaa gcugaaccug acccugcacc      960

agagcgccca gcugagcgug cugcugaccg uggaggagca ggacagaaag gagccccaca     1020

gcagcgacac cgagcugccc aaggacaagc ugagcagcgc cgacgaccac agagugaaca     1080

gcggcuucgg cagaggccug agcgacaaga agagcggcga gagccaggug cuguucgaga     1140

ccgagaucag cagaaagcug uucgacaccc ugaacgagga ccuguuccag aagauccugg     1200

ugcccaucca gcaggugcug aaggagggcc accuggagaa gaccgagauc gacgaggugg     1260

ugcugguggg cggcagcacc agaaucccca gaaucagaca ggugauccag gaguucuucg     1320

gcaaggaccc caacaccagc guggaccccg accuggccgu ggugaccggc guggccaucc     1380

aggccggcau cgacggcggc agcuggcccc ugcaggugag cgcccuggag auccccaaca     1440

agcaccugca gaagaccaac uucaacugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3027
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt4)

<400>  3027
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ccaucggcgu gcaccugggc ugcaccagcg ccugcguggc cguguacaag gacggcagag      120

ccggcguggu ggccaacgac gccggcgaca gagugacccc cgccguggug gccuacagcg      180

agaacgagga gaucgugggc cuggccgcca agcagagcag aaucagaaac aucagcaaca      240

ccgugaugaa ggugaagcag auccugggca gaagcagcag cgacccccag gcccagaagu      300

acaucgccga gagcaagugc cuggugaucg agaagaacgg caagcugaga uacgagaucg      360

acaccggcga ggagaccaag uucgugaacc ccgaggacgu ggccagacug aucuucagca      420

agaugaagga gaccgcccac agcgugcugg gcagcgacgc caacgacgug gugaucaccg      480

ugcccuucga cuucggcgag aagcagaaga acgcccuggg cgaggccgcc agagccgccg      540

gcuucaacgu gcugagacug auccacgagc ccagcgccgc ccugcuggcc uacggcaucg      600

gccaggacag ccccaccggc aagagcaaca uccugguguu caagcugggc ggcaccagcc      660

ugagccugag cgugauggag gugaacagcg gcaucuacag agugcugagc accaacaccg      720

acgacaacau cggcggcgcc cacuucaccg agacccuggc ccaguaccug gccagcgagu      780

uccagagaag cuucaagcac gacgugagag gcaacgccag agccaugaug aagcugacca      840

acagcgccga gguggccaag cacagccuga gcacccuggg cagcgccaac ugcuuccugg      900

acagccugua cgagggccag gacuucgacu gcaacgugag cagagccaga uucgagcugc      960

ugugcagccc ccuguucaac aagugcaucg aggccaucag aggccugcug gaccagaacg     1020

gcuucaccgc cgacgacauc aacaaggugg ugcugugcgg cggcagcagc agaaucccca     1080

agcugcagca gcugaucaag gaccuguucc ccgccgugga gcugcugaac agcauccccc     1140

ccgacgaggu gauccccauc ggcgccgcca ucgaggccgg cauccugauc ggcaaggaga     1200

accugcuggu ggaggacagc cugaugaucg agugcagcgc cagagacauc cuggugaagg     1260

gcguggacga gagcggcgcc agcagauuca ccgugcuguu ccccagcggc accccccugc     1320

ccgccagaag acagcacacc cugcaggccc ccggcagcau cagcagcgug ugccuggagc     1380

uguacgagag cgacggcaag aacagcgcca aggaggagac caaguucgcc cagguggugc     1440

ugcaggaccu ggacaagaag gagaacggcc ugagagacau ccuggccgug cugaccauga     1500

agagagacgg cagccugcac gugaccugca ccgaccagga gaccggcaag ugcgaggcca     1560

ucagcaucga gaucgccagc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  3028
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt4)

<400>  3028
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggugggccu ggacgugggc agccagagcu gcuacaucgc cguggccaga gccggcggca      120

ucgagaccau cgccaacgag uucagcgaca gaugcacccc cagcgugauc agcuucggca      180

gcaagaacag aaccaucggc guggccgcca agaaccagca gaucacccac gccaacaaca      240

ccgugagcaa cuucaagaga uuccacggca gagccuucaa cgaccccuuc auccagaagg      300

agaaggagaa ccugagcuac gaccuggugc cccugaagaa cggcggcgug ggcaucaagg      360

ugauguacau gggcgaggag caccuguuca gcguggagca gaucaccgcc augcugcuga      420

ccaagcugaa ggagaccgcc gagaacagcc ugaagaagcc cgugaccgac ugcgugauca      480

gcgugcccag cuucuucacc gacgccgaga gaagaagcgu gcuggacgcc gcccagaucg      540

ugggccugaa cugccugaga cugaugaacg acaugaccgc cguggcccug aacuacggca      600

ucuacaagca ggaccugccc agccuggacg agaagcccag aaucguggug uucguggaca      660

ugggccacag cgccuuccag gugagcgccu gcgccuucaa caagggcaag cugaaggugc      720

ugggcaccgc cuucgacccc uuccugggcg gcaagaacuu cgacgagaag cugguggagc      780

acuucugcgc cgaguucaag accaaguaca agcuggacgc caagagcaag aucagagccc      840

ugcugagacu guaccaggag ugcgagaagc ugaagaagcu gaugagcagc aacagcaccg      900

accugccccu gaacaucgag ugcuucauga acgacaagga cgugagcggc aagaugaaca      960

gaagccaguu cgaggagcug ugcgccgagc ugcugcagaa gaucgaggug ccccuguaca     1020

gccugcugga gcagacccac cugaaggugg aggacgugag cgccguggag aucgugggcg     1080

gcgccaccag aauccccgcc gugaaggaga gaaucgccaa guucuucggc aaggacauca     1140

gcaccacccu gaacgccgac gaggccgugg ccagaggcug cgcccugcag ugcgccaucc     1200

ugagccccgc cuucaaggug agagaguuca gcgugaccga cgccgugccc uuccccauca     1260

gccugaucug gaaccacgac agcgaggaca ccgagggcgu gcacgaggug uucagcagaa     1320

accacgccgc ccccuucagc aaggugcuga ccuuccugag aagaggcccc uucgagcugg     1380

aggccuucua cagcgacccc cagggcgugc ccuaccccga ggccaagauc ggcagauucg     1440

uggugcagaa cgugagcgcc cagaaggacg gcgagaagag cagagugaag gugaagguga     1500

gagugaacac ccacggcauc uucaccauca gcaccgccag caugguggag aaggugccca     1560

ccgaggagaa cgagaugagc agcgaggccg acauggagug ccugaaccag agaccccccg     1620

agaaccccga caccgacaag aacgugcagc aggacaacag cgaggccggc acccagcccc     1680

aggugcagac cgacgcccag cagaccagcc agagcccccc cagccccgag cugaccagcg     1740

aggagaacaa gauccccgac gccgacaagg ccaacgagaa gaagguggac cagccccccg     1800

aggccaagaa gcccaagauc aaggugguga acguggagcu gcccaucgag gccaaccugg     1860

uguggcagcu gggcaaggac cugcugaaca uguacaucga gaccgagggc aagaugauca     1920

ugcaggacaa gcuggagaag gagagaaacg acgccaagaa cgccguggag gaguacgugu     1980

acgaguucag agacaagcug ugcggccccu acgagaaguu caucugcgag caggaccacc     2040

agaacuuccu gagacugcug accgagaccg aggacuggcu guacgaggag ggcgaggacc     2100

aggccaagca ggccuacgug gacaagcugg aggagcugau gaagaucggc acccccguga     2160

aggugagauu ccaggaggcc gaggagagac ccaagauguu cgaggagcug ggccagagac     2220

ugcagcacua cgccaagauc gccgccgacu ucagaaacaa ggacgagaag uacaaccaca     2280

ucgacgagag cgagaugaag aagguggaga agagcgugaa cgaggugaug gaguggauga     2340

acaacgugau gaacgcccag gccaagaaga gccuggacca ggaccccgug gugagagccc     2400

aggagaucaa gaccaagauc aaggagcuga acaacaccug cgagcccgug gugacccagc     2460

ccaagcccaa gaucgagagc cccaagcugg agagaacccc caacggcccc aacaucgaca     2520

agaaggagga ggaccuggag gacaagaaca acuucggcgc cgagcccccc caccagaacg     2580

gcgagugcua ccccaacgag aagaacagcg ugaacaugga ccuggacuga ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  3029
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt4)

<400>  3029
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaggugag aagacagaga cccagaagaa gagugugcug ggcccuggug gccgugcugc      120

uggccgaccu gcuggcccug agcgacaccc uggccgugau gagcguggac cugggcagcg      180

agagcaugaa gguggccauc gugaagcccg gcgugcccau ggagaucgug cugaacaagg      240

agagcagaag aaagaccccc gugaucguga cccugaagga gaacgagaga uucuucggcg      300

acagcgccgc cagcauggcc aucaagaacc ccaaggccac ccugagauac uuccagcacc      360

ugcugggcaa gcaggccgac aacccccacg uggcccugua ccaggccaga uuccccgagc      420

acgagcugac cuucgacccc cagagacaga ccgugcacuu ccagaucagc agccagcugc      480

aguucagccc cgaggaggug cugggcaugg ugcugaacua cagcagaagc cuggccgagg      540

acuucgccga gcagcccauc aaggacgccg ugaucaccgu gcccguguuc uucaaccagg      600

ccgagagaag agccgugcug caggccgcca gaauggccgg ccugaaggug cugcagcuga      660

ucaacgacaa caccgccacc gcccugagcu acggcguguu cagaagaaag gacaucaaca      720

ccaccgccca gaacaucaug uucuacgaca ugggcagcgg cagcaccgug ugcaccaucg      780

ugaccuacca gauggugaag accaaggagg ccggcaugca gccccagcug cagaucagag      840

gcgugggcuu cgacagaacc cugggcggcc uggagaugga gcugagacug agagagagac      900

uggccggccu guucaacgag cagagaaagg gccagagagc caaggacgug agagagaacc      960

ccagagccau ggccaagcug cugagagagg ccaacagacu gaagaccgug cugagcgcca     1020

acgccgacca cauggcccag aucgagggcc ugauggacga cguggacuuc aaggccaagg     1080

ugaccagagu ggaguucgag gagcugugcg ccgaccuguu cgagagagug cccggccccg     1140

ugcagcaggc ccugcagagc gccgagauga gccuggacga gaucgagcag gugauccugg     1200

ugggcggcgc caccagagug cccagagugc aggaggugcu gcugaaggcc gugggcaagg     1260

aggagcuggg caagaacauc aacgccgacg aggccgccgc caugggcgcc guguaccagg     1320

ccgccgcccu gagcaaggcc uucaagguga agcccuucgu ggugagagac gccguggugu     1380

accccauccu gguggaguuc accagagagg uggaggagga gcccggcauc cacagccuga     1440

agcacaacaa gagagugcug uucagcagaa ugggccccua cccccagaga aaggugauca     1500

ccuucaacag auacagccac gacuucaacu uccacaucaa cuacggcgac cugggcuucc     1560

ugggccccga ggaccugaga guguucggca gccagaaccu gaccaccgug aagcugaagg     1620

gcgugggcga cagcuucaag aaguaccccg acuacgagag caagggcauc aaggcccacu     1680

ucaaccugga cgagagcggc gugcugagcc uggacagagu ggagagcgug uucgagaccc     1740

ugguggagga cagcgccgag gaggagagca cccugaccaa gcugggcaac accaucagca     1800

gccuguucgg cggcggcacc acccccgacg ccaaggagaa cggcaccgac accgugcagg     1860

aggaggagga gagccccgcc gagggcagca aggacgagcc cggcgagcag guggagcuga     1920

aggaggaggc cgaggccccc guggaggacg gcagccagcc cccccccccc gagcccaagg     1980

gcgacgccac ccccgagggc gagaaggcca ccgagaagga gaacggcgac aagagcgagg     2040

cccagaagcc cagcgagaag gccgaggccg gccccgaggg cguggccccc gcccccgagg     2100

gcgagaagaa gcagaagccc gccagaaaga gaagaauggu ggaggagauc ggcguggagc     2160

ugguggugcu ggaccugccc gaccugcccg aggacaagcu ggcccagagc gugcagaagc     2220

ugcaggaccu gacccugaga gaccuggaga agcaggagag agagaaggcc gccaacagcc     2280

uggaggccuu caucuucgag acccaggaca agcuguacca gcccgaguac caggagguga     2340

gcaccgagga gcagagagag gagaucagcg gcaagcugag cgccgccagc accuggcugg     2400

aggacgaggg cgugggcgcc accaccguga ugcugaagga gaagcuggcc gagcugagaa     2460

agcugugcca gggccuguuc uucagagugg aggagagaaa gaaguggccc gagagacuga     2520

gcgcccugga caaccugcug aaccacagca gcauguuccu gaagggcgcc agacugaucc     2580

ccgagaugga ccagaucuuc accgaggugg agaugaccac ccuggagaag gugaucaacg     2640

agaccugggc cuggaagaac gccacccugg ccgagcaggc caagcugccc gccaccgaga     2700

agcccgugcu gcugagcaag gacaucgagg ccaagaugau ggcccuggac agagaggugc     2760

aguaccugcu gaacaaggcc aaguucacca agcccagacc cagacccaag gacaagaacg     2820

gcaccagagc cgagcccccc cugaacgcca gcgccagcga ccagggcgag aaggugaucc     2880

cccccgccgg ccagaccgag gacgccgagc ccaucagcga gcccgagaag guggagaccg     2940

gcagcgagcc cggcgacacc gagccccugg agcugggcgg ccccggcgcc gagcccgagc     3000

agaaggagca gagcaccggc cagaagagac cccugaagaa cgacgagcug ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3030
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt4)

<400>  3030
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggagaccca gacccaggac cagcccaugg aggaggagga gguggagacc uucgccuucc      120

aggccgagau cgcccagcug augagccuga ucaucaacac cuucuacagc aacaaggaga      180

ucuuccugag agagcugauc agcaacagca gcgacgcccu ggacaagauc agauacgaga      240

gccugaccga ccccagcaag cuggacagcg gcaaggagcu gcacaucaac cugaucccca      300

acaagcagga cagaacccug accaucgugg acaccggcau cggcaugacc aaggccgacc      360

ugaucaacaa ccugggcacc aucgccaaga gcggcaccaa ggccuucaug gaggcccugc      420

aggccggcgc cgacaucagc augaucggcc aguucggcgu gggcuucuac agcgccuacc      480

ugguggccga gaaggugacc gugaucacca agcacaacga cgacgagcag uacgccuggg      540

agagcagcgc cggcggcagc uucaccguga gaaccgacac cggcgagccc augggcagag      600

gcaccaaggu gauccugcac cugaaggagg accagaccga guaccuggag gagagaagaa      660

ucaaggagau cgugaagaag cacagccagu ucaucggcua ccccaucacc cuguucgugg      720

agaaggagag agacaaggag gugagcgacg acgaggccga ggagaaggag gacaaggagg      780

aggagaagga gaaggaggag aaggagagcg aggacaagcc cgagaucgag gacgugggca      840

gcgacgagga ggaggagaag aaggacggcg acaagaagaa gaagaagaag aucaaggaga      900

aguacaucga ccaggaggag cugaacaaga ccaagcccau cuggaccaga aaccccgacg      960

acaucaccaa cgaggaguac ggcgaguucu acaagagccu gaccaacgac ugggaggacc     1020

accuggccgu gaagcacuuc agcguggagg gccagcugga guucagagcc cugcuguucg     1080

ugcccagaag agcccccuuc gaccuguucg agaacagaaa gaagaagaac aacaucaagc     1140

uguacgugag aagaguguuc aucauggaca acugcgagga gcugaucccc gaguaccuga     1200

acuucaucag aggcguggug gacagcgagg accugccccu gaacaucagc agagagaugc     1260

ugcagcagag caagauccug aaggugauca gaaagaaccu ggugaagaag ugccuggagc     1320

uguucaccga gcuggccgag gacaaggaga acuacaagaa guucuacgag caguucagca     1380

agaacaucaa gcugggcauc cacgaggaca gccagaacag aaagaagcug agcgagcugc     1440

ugagauacua caccagcgcc agcggcgacg agauggugag ccugaaggac uacugcacca     1500

gaaugaagga gaaccagaag cacaucuacu acaucaccgg cgagaccaag gaccaggugg     1560

ccaacagcgc cuucguggag agacugagaa agcacggccu ggaggugauc uacaugaucg     1620

agcccaucga cgaguacugc gugcagcagc ugaaggaguu cgagggcaag acccugguga     1680

gcgugaccaa ggagggccug gagcugcccg aggacgagga ggagaagaag aagcaggagg     1740

agaagaagac caaguucgag aaccugugca agaucaugaa ggacauccug gagaagaagg     1800

uggagaaggu gguggugagc aacagacugg ugaccagccc cugcugcauc gugaccagca     1860

ccuacggcug gaccgccaac auggagagaa ucaugaaggc ccaggcccug agagacaaca     1920

gcaccauggg cuacauggcc gccaagaagc accuggagau caaccccgac cacagcauca     1980

ucgagacccu gagacagaag gccgaggccg acaagaacga caagagcgug aaggaccugg     2040

ugauccugcu guacgagacc gcccugcuga gcagcggcuu cagccuggag gacccccaga     2100

cccacgccaa cagaaucuac agaaugauca agcugggccu gggcaucgac gaggacgacc     2160

ccaccgccga cgacaccagc gccgccguga ccgaggagau gcccccccug gagggcgacg     2220

acgacaccag cagaauggag gagguggacu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  3031
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt4)

<400>  3031
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcagcaagcu ggacagcggc aagggccugc acaucaaccu ggugcccaac aagcagaacc      120

agacccugac caucguggac accagaaucg gcaugaccaa gaccgaccug aucaacaacc      180

ugggcaccgu gaccaagagc ggcaccaagg ccuucaugga ggcccugcag gccgacgccg      240

acaucagcau gaucggccac uucggcgugg gcuucuacag cgccuaccug guggccaaga      300

aggugaccgu gaucagcaag cacaacaacg acgagcagua caccugggag agcagcgccg      360

gcggcagcuu caccgugaga accgacgagu gaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  3032
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt4)

<400>  3032
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggaggugca ccacggcgag gaggaggugg agaccuucgc cuuccaggcc gagaucgccc      120

agcugaugag ccugaucauc aacaccuucu acagcaacaa ggagaucuuc cugagagagc      180

ugaucagcaa cgccagcgac gcccuggaca agaucagaua cgagagccug accgacccca      240

gcaagcugga cagcggcaag gagcugaaga ucgacaucau ccccaacccc caggagagaa      300

cccugacccu gguggacacc ggcaucggca ugaccaaggc cgaccugauc aacaaccugg      360

gcaccaucgc caagagcggc accaaggccu ucauggaggc ccugcaggcc ggcgccgaca      420

ucagcaugau cggccaguuc ggcgugggcu ucuacagcgc cuaccuggug gccgagaagg      480

ugguggugau caccaagcac aacgacgacg agcaguacgc cugggagagc agcgccggcg      540

gcagcuucac cgugagagcc gaccacggcg agcccaucgg cagaggcacc aaggugaucc      600

ugcaccugaa ggaggaccag accgaguacc uggaggagag aagagugaag gaggugguga      660

agaagcacag ccaguucauc ggcuacccca ucacccugua ccuggagaag gagagagaga      720

aggagaucag cgacgacgag gccgaggagg agaagggcga gaaggaggag gaggacaagg      780

acgacgagga gaagcccaag aucgaggacg ugggcagcga cgaggaggac gacagcggca      840

aggacaagaa gaagaagacc aagaagauca aggagaagua caucgaccag gaggagcuga      900

acaagaccaa gcccaucugg accagaaacc ccgacgacau cacccaggag gaguacggcg      960

aguucuacaa gagccugacc aacgacuggg aggaccaccu ggccgugaag cacuucagcg     1020

uggagggcca gcuggaguuc agagcccugc uguucauccc cagaagagcc cccuucgacc     1080

uguucgagaa caagaagaag aagaacaaca ucaagcugua cgugagaaga guguucauca     1140

uggacagcug cgacgagcug auccccgagu accugaacuu caucagaggc gugguggaca     1200

gcgaggaccu gccccugaac aucagcagag agaugcugca gcagagcaag auccugaagg     1260

ugaucagaaa gaacaucgug aagaagugcc uggagcuguu cagcgagcug gccgaggaca     1320

aggagaacua caagaaguuc uacgaggccu ucagcaagaa ccugaagcug ggcauccacg     1380

aggacagcac caacagaaga agacugagcg agcugcugag auaccacacc agccagagcg     1440

gcgacgagau gaccagccug agcgaguacg ugagcagaau gaaggagacc cagaagagca     1500

ucuacuacau caccggcgag agcaaggagc agguggccaa cagcgccuuc guggagagag     1560

ugagaaagag aggcuucgag gugguguaca ugaccgagcc caucgacgag uacugcgugc     1620

agcagcugaa ggaguucgac ggcaagagcc uggugagcgu gaccaaggag ggccuggagc     1680

ugcccgagga cgaggaggag aagaagaaga uggaggagag caaggccaag uucgagaacc     1740

ugugcaagcu gaugaaggag auccuggaca agaaggugga gaaggugacc aucagcaaca     1800

gacuggugag cagccccugc ugcaucguga ccagcaccua cggcuggacc gccaacaugg     1860

agagaaucau gaaggcccag gcccugagag acaacagcac caugggcuac augauggcca     1920

agaagcaccu ggagaucaac cccgaccacc ccaucgugga gacccugaga cagaaggccg     1980

aggccgacaa gaacgacaag gccgugaagg accugguggu gcugcuguuc gagaccgccc     2040

ugcugagcag cggcuucagc cuggaggacc cccagaccca cagcaacaga aucuacagaa     2100

ugaucaagcu gggccugggc aucgacgagg acgagguggc cgccgaggag cccaacgccg     2160

ccgugcccga cgagaucccc ccccuggagg gcgacgagga cgccagcaga auggaggagg     2220

uggacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  3033
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt4)

<400>  3033
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagag       60

cccugugggu gcugggccug ugcugcgugc ugcugaccuu cggcagcgug agagccgacg      120

acgaggugga cguggacggc accguggagg aggaccuggg caagagcaga gagggcagca      180

gaaccgacga cgagguggug cagagagagg aggaggccau ccagcuggac ggccugaacg      240

ccagccagau cagagagcug agagagaaga gcgagaaguu cgccuuccag gccgagguga      300

acagaaugau gaagcugauc aucaacagcc uguacaagaa caaggagauc uuccugagag      360

agcugaucag caacgccagc gacgcccugg acaagaucag acugaucagc cugaccgacg      420

agaacgcccu gagcggcaac gaggagcuga ccgugaagau caagugcgac aaggagaaga      480

accugcugca cgugaccgac accggcgugg gcaugaccag agaggagcug gugaagaacc      540

ugggcaccau cgccaagagc ggcaccagcg aguuccugaa caagaugacc gaggcccagg      600

aggacggcca gagcaccagc gagcugaucg gccaguucgg cgugggcuuc uacagcgccu      660

uccugguggc cgacaaggug aucgugacca gcaagcacaa caacgacacc cagcacaucu      720

gggagagcga cagcaacgag uucagcguga ucgccgaccc cagaggcaac acccugggca      780

gaggcaccac caucacccug gugcugaagg aggaggccag cgacuaccug gagcuggaca      840

ccaucaagaa ccuggugaag aaguacagcc aguucaucaa cuuccccauc uacgugugga      900

gcagcaagac cgagaccgug gaggagccca uggaggagga ggaggccgcc aaggaggaga      960

aggaggagag cgacgacgag gccgccgugg aggaggagga ggaggagaag aagcccaaga     1020

ccaagaaggu ggagaagacc gugugggacu gggagcugau gaacgacauc aagcccaucu     1080

ggcagagacc cagcaaggag guggaggagg acgaguacaa ggccuucuac aagagcuuca     1140

gcaaggagag cgacgacccc auggccuaca uccacuucac cgccgagggc gaggugaccu     1200

ucaagagcau ccuguucgug cccaccagcg cccccagagg ccuguucgac gaguacggca     1260

gcaagaagag cgacuacauc aagcuguacg ugagaagagu guucaucacc gacgacuucc     1320

acgacaugau gcccaaguac cugaacuucg ugaagggcgu gguggacagc gacgaccugc     1380

cccugaacgu gagcagagag acccugcagc agcacaagcu gcugaaggug aucagaaaga     1440

agcuggugag aaagacccug gacaugauca agaagaucgc cgacgacaag uacaacgaca     1500

ccuucuggaa ggaguucggc accaacauca agcugggcgu gaucgaggac cacagcaaca     1560

gaaccagacu ggccaagcug cugagauucc agagcagcca ccaccccacc gacaucacca     1620

gccuggacca guacguggag agaaugaagg agaagcagga caagaucuac uucauggccg     1680

gcagcagcag aaaggaggcc gagagcagcc ccuucgugga gagacugcug aagaagggcu     1740

acgaggugau cuaccugacc gagcccgugg acgaguacug cauccaggcc cugcccgagu     1800

ucgacggcaa gagauuccag aacguggcca aggagggcgu gaaguucgac gagagcgaga     1860

agaccaagga gagcagagag gccguggaga aggaguucga gccccugcug aacuggauga     1920

aggacaaggc ccugaaggac aagaucgaga aggccguggu gagccagaga cugaccgaga     1980

gccccugcgc ccugguggcc agccaguacg gcuggagcgg caacauggag agaaucauga     2040

aggcccaggc cuaccagacc ggcaaggaca ucagcaccaa cuacuacgcc agccagaaga     2100

agaccuucga gaucaacccc agacaccccc ugaucagaga caugcugaga agaaucaagg     2160

aggacgagga cgacaagacc gugcuggacc uggccguggu gcuguucgag accgccaccc     2220

ugagaagcgg cuaccugcug cccgacacca aggccuacgg cgacagaauc gagagaaugc     2280

ugagacugag ccugaacauc gaccccgacg ccaaggugga ggaggagccc gaggaggagc     2340

ccgaggagac cgccgaggac accaccgagg acaccgagca ggacgaggac gaggagaugg     2400

acgugggcac cgacgaggag gaggagaccg ccaaggagag caccgccgag aaggacgagc     2460

ugugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  3034
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt4)

<400>  3034
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

gagagcugag agcccugcug cuguggggca gaagacugag accccugcug agagcccccg      120

cccuggccgc cgugcccggc ggcaagccca uccugugccc cagaagaacc accgcccagc      180

ugggccccag aagaaacccc gccuggagcc ugcaggccgg cagacuguuc agcacccaga      240

ccgccgagga caaggaggag ccccugcaca gcaucaucag cagcaccgag agcgugcagg      300

gcagcaccag caagcacgag uuccaggccg agaccaagaa gcugcuggac aucguggcca      360

gaagccugua cagcgagaag gagguguuca ucagagagcu gaucagcaac gccagcgacg      420

cccuggagaa gcugagacac aagcugguga gcgacggcca ggcccugccc gagauggaga      480

uccaccugca gaccaacgcc gagaagggca ccaucaccau ccaggacacc ggcaucggca      540

ugacccagga ggagcuggug agcaaccugg gcaccaucgc cagaagcggc agcaaggccu      600

uccuggacgc ccugcagaac caggccgagg ccagcagcaa gaucaucggc caguucggcg      660

ugggcuucua cagcgccuuc augguggccg acagagugga gguguacagc agaagcgccg      720

cccccggcag ccugggcuac caguggcuga gcgacggcag cggcguguuc gagaucgccg      780

aggccagcgg cgugagaacc ggcaccaaga ucaucaucca ccugaagagc gacugcaagg      840

aguucagcag cgaggccaga gugagagacg uggugaccaa guacagcaac uucgugagcu      900

ucccccugua ccugaacggc agaagaauga acacccugca ggccaucugg augauggacc      960

ccaaggacgu gagagagugg cagcacgagg aguucuacag auacguggcc caggcccacg     1020

acaagcccag auacacccug cacuacaaga ccgacgcccc ccugaacauc agaagcaucu     1080

ucuacgugcc cgacaugaag cccagcaugu ucgacgugag cagagagcug ggcagcagcg     1140

uggcccugua cagcagaaag gugcugaucc agaccaaggc caccgacauc cugcccaagu     1200

ggcugagauu caucagaggc gugguggaca gcgaggacau cccccugaac cugagcagag     1260

agcugcugca ggagagcgcc cugaucagaa agcugagaga cgugcugcag cagagacuga     1320

ucaaguucuu caucgaccag agcaagaagg acgccgagaa guacgccaag uucuucgagg     1380

acuacggccu guucaugaga gagggcaucg ugaccgccac cgagcaggag gugaaggagg     1440

acaucgccaa gcugcugaga uacgagagca gcgcccugcc cagcggccag cugaccagcc     1500

ugagcgagua cgccagcaga augagagccg gcaccagaaa caucuacuac cugugcgccc     1560

ccaacagaca ccuggccgag cacagccccu acuacgaggc caugaagaag aaggacaccg     1620

aggugcuguu cugcuucgag caguucgacg agcugacccu gcugcaccug agagaguucg     1680

acaagaagaa gcugaucagc guggagaccg acaucguggu ggaccacuac aaggaggaga     1740

aguucgagga cagaagcccc gccgccgagu gccugagcga gaaggagacc gaggagcuga     1800

uggccuggau gagaaacgug cugggcagca gagugaccaa cgugaaggug acccugagac     1860

uggacaccca ccccgccaug gugaccgugc uggagauggg cgccgccaga cacuuccuga     1920

gaaugcagca gcuggccaag acccaggagg agagagccca gcugcugcag cccacccugg     1980

agaucaaccc cagacacgcc cugaucaaga agcugaacca gcugagagcc agcgagcccg     2040

gccuggccca gcugcuggug gaccagaucu acgagaacgc caugaucgcc gccggccugg     2100

uggacgaccc cagagccaug gugggcagac ugaacgagcu gcuggugaag gcccuggaga     2160

gacacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  3035
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt4)

<400>  3035
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

agaucagcag ccugcccacc cagcuguuca agugcugcuu cugcgacuuc cugaagguga      120

agaugcacac caugagcagc agccaccugu ucuaccuggc ccugugccug cugaccuuca      180

ccagcagcgc caccgccggc cccgagaccc ugugcggcgc cgagcuggug gacgcccugc      240

aguucgugug cggcgacaga ggcuucuacu ucaacaagcc caccggcuac ggcagcagca      300

gcagaagagc cccccagacc ggcaucgugg acgagugcug cuucagaagc ugcgaccuga      360

gaagacugga gauguacugc gccccccuga agcccgccaa gagcgccaga agcgugagag      420

cccagagaca caccgacaug cccaagaccc agaaggaggu gcaccugaag aacgccagca      480

gaggcagcgc cggcaacaag aacuacagaa ugugaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  3036
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt4)

<400>  3036
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

uccccauggg caagagcaug cuggugcugc ugaccuuccu ggccuucgcc agcugcugca      120

ucgccgccua cagacccagc gagacccugu gcggcggcga gcugguggac acccugcagu      180

ucgugugcgg cgacagaggc uucuacuuca gcagacccgc cagcagagug agcagaagaa      240

gcagaggcau cguggaggag ugcugcuuca gaagcugcga ccuggcccug cuggagaccu      300

acugcgccac ccccgccaag agcgagagag acgugagcac cccccccacc gugcugcccg      360

acaacuuccc cagauacccc gugggcaagu ucuuccagua cgacaccugg aagcagagca      420

cccagagacu gagaagaggc cugcccgccc ugcugagagc cagaagaggc cacgugcugg      480

ccaaggagcu ggaggccuuc agagaggcca agagacacag accccugauc gcccugccca      540

cccaggaccc cgcccacggc ggcgcccccc ccgagauggc cagcaacaga aagugaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  3037
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt4)

<400>  3037
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaca       60

gcuucagcac cagcgccuuc ggccccgugg ccuucagccu gggccugcug cuggugcugc      120

ccgccgccuu ccccgccccc gugccccccg gcgaggacag caaggacgug gccgcccccc      180

acagacagcc ccugaccagc agcgagagaa ucgacaagca gaucagauac auccuggacg      240

gcaucagcgc ccugagaaag gagaccugca acaagagcaa caugugcgag agcagcaagg      300

aggcccuggc cgagaacaac cugaaccugc ccaagauggc cgagaaggac ggcugcuucc      360

agagcggcuu caacgaggag accugccugg ugaagaucau caccggccug cuggaguucg      420

agguguaccu ggaguaccug cagaacagau ucgagagcag cgaggagcag gccagagccg      480

ugcagaugag caccaaggug cugauccagu uccugcagaa gaaggccaag aaccuggacg      540

ccaucaccac ccccgacccc accaccaacg ccagccugcu gaccaagcug caggcccaga      600

accaguggcu gcaggacaug accacccacc ugauccugag aagcuucaag gaguuccugc      660

agagcagccu gagagcccug agacagaugu gaggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  3038
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt4)

<400>  3038
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugcuguggcu gagaggcuuc cugcuggcca gcugcuggau caucgugaga agcagcccca      120

cccccggcag cgagggccac agcgccgccc ccgacugccc cagcugcgcc cuggccgccc      180

ugcccaagga cgugcccaac agccagcccg agauggugga ggccgugaag aagcacaucc      240

ugaacaugcu gcaccugaag aagagacccg acgugaccca gcccgugccc aaggccgccc      300

ugcugaacgc caucagaaag cugcacgugg gcaagguggg cgagaacggc uacguggaga      360

ucgaggacga caucggcaga agagccgaga ugaacgagcu gauggagcag accagcgaga      420

ucaucaccuu cgccgagagc ggcaccgcca gaaagacccu gcacuucgag aucagcaagg      480

agggcagcga ccugagcgug guggagagag ccgaggugug gcuguuccug aaggugccca      540

aggccaacag aaccagaacc aaggugacca ucagacuguu ccagcagcag aagcaccccc      600

agggcagccu ggacaccggc gaggaggccg aggagguggg ccugaagggc gagagaagcg      660

agcugcugcu gagcgagaag gugguggacg ccagaaagag caccuggcac guguuccccg      720

ugagcagcag cauccagaga cugcuggacc agggcaagag cagccuggac gugagaaucg      780

ccugcgagca gugccaggag agcggcgcca gccuggugcu gcugggcaag aagaagaaga      840

aggaggagga gggcgagggc aagaagaagg gcggcggcga gggcggcgcc ggcgccgacg      900

aggagaagga gcagagccac agacccuucc ugaugcugca ggccagacag agcgaggacc      960

acccccacag aagaagaaga agaggccugg agugcgacgg caaggugaac aucugcugca     1020

agaagcaguu cuucgugagc uucaaggaca ucggcuggaa cgacuggauc aucgccccca     1080

gcggcuacca cgccaacuac ugcgagggcg agugccccag ccacaucgcc ggcaccagcg     1140

gcagcagccu gagcuuccac agcaccguga ucaaccacua cagaaugaga ggccacagcc     1200

ccuucgccaa ccugaagagc ugcugcgugc ccaccaagcu gagacccaug agcaugcugu     1260

acuacgacga cggccagaac aucaucaaga aggacaucca gaacaugauc guggaggagu     1320

gcggcugcag cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  3039
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt4)

<400>  3039
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacg       60

gccugcccgg cagagcccug ggcgccgccu gccugcugcu gcuggccgcc ggcuggcugg      120

gccccgaggc cuggggcagc cccacccccc cccccacccc cgccgccccc cccccccccc      180

ccccccccgg cagccccggc ggcagccagg acaccugcac cagcugcggc ggcuucagaa      240

gacccgagga gcugggcaga guggacggcg acuuccugga ggccgugaag agacacaucc      300

ugagcagacu gcagaugaga ggcagaccca acaucaccca cgccgugccc aaggccgcca      360

uggugaccgc ccugagaaag cugcacgccg gcaaggugag agaggacggc agaguggaga      420

ucccccaccu ggacggccac gccagccccg gcgccgacgg ccaggagaga gugagcgaga      480

ucaucagcuu cgccgagacc gacggccugg ccagcagcag agugagacug uacuucuuca      540

ucagcaacga gggcaaccag aaccuguucg uggugcaggc cagccugugg cuguaccuga      600

agcugcugcc cuacgugcug gagaagggca gcagaagaaa ggugagagug aagguguacu      660

uccaggagca gggccacggc gacagaugga acauggugga gaagagagug gaccugaaga      720

gaagcggcug gcacaccuuc ccccugaccg aggccaucca ggcccuguuc gagagaggcg      780

agagaagacu gaaccuggac gugcagugcg acagcugcca ggagcuggcc guggugcccg      840

uguucgugga ccccggcgag gagagccaca gacccuucgu gguggugcag gccagacugg      900

gcgacagcag acacagaauc agaaagagag gccuggagug cgacggcaga accaaccugu      960

gcugcagaca gcaguucuuc aucgacuuca gacugaucgg cuggaacgac uggaucaucg     1020

cccccaccgg cuacuacggc aacuacugcg agggcagcug ccccgccuac cuggccggcg     1080

ugcccggcag cgccagcagc uuccacaccg ccguggugaa ccaguacaga augagaggcc     1140

ugaaccccgg caccgugaac agcugcugca uccccaccaa gcugagcacc augagcaugc     1200

uguacuucga cgacgaguac aacaucguga agagagacgu gcccaacaug aucguggagg     1260

agugcggcug cgccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  3040
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt4)

<400>  3040
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ugagagugcu gcugcugacc gcccugaccc ugugccacgg cuucaaccug gacaccgaga      120

acgccaugac cuuccaggag aacgccagag gcuucggcca gagcguggug cagcugcagg      180

gcagcagagu gguggugggc gccccccagg agaucguggc cgccaaccag agaggcagcc      240

uguaccagug cgacuacagc accggcagcu gcgagcccau cagacugcag gugcccgugg      300

aggccgugaa caugagccug ggccugagcc uggccgccac caccagcccc ccccagcugc      360

uggccugcgg ccccaccgug caccagaccu gcagcgagaa caccuacgug aagggccugu      420

gcuuccuguu cggcagcaac cugagacagc agccccagaa guuccccgag gcccugagag      480

gcugccccca ggaggacagc gacaucgccu uccugaucga cggcagcggc agcaucaucc      540

cccacgacuu cagaagaaug aaggaguucg ugagcaccgu gauggagcag cugaagaaga      600

gcaagacccu guucagccug augcaguaca gcgaggaguu cagaauccac uucaccuuca      660

aggaguucca gaacaacccc aaccccagaa gccuggugaa gcccaucacc cagcugcugg      720

gcagaaccca caccgccacc ggcaucagaa agguggugag agagcuguuc aacaucacca      780

acggcgccag aaagaacgcc uucaagaucc ugguggugau caccgacggc gagaaguucg      840

gcgacccccu gggcuacgag gacgugaucc ccgaggccga cagagagggc gugaucagau      900

acgugaucgg cgugggcgac gccuucagaa gcgagaagag cagacaggag cugaacacca      960

ucgccagcaa gccccccaga gaccacgugu uccaggugaa caacuucgag gcccugaaga     1020

ccauccagaa ccagcugaga gagaagaucu ucgccaucga gggcacccag accggcagca     1080

gcagcagcuu cgagcacgag augagccagg agggcuucag cgccgccauc accagcaacg     1140

gcccccugcu gagcaccgug ggcagcuacg acugggccgg cggcguguuc cuguacacca     1200

gcaaggagaa gagcaccuuc aucaacauga ccagagugga cagcgacaug aacgacgccu     1260

accugggcua cgccgccgcc aucauccuga gaaacagagu gcagagccug gugcugggcg     1320

cccccagaua ccagcacauc ggccuggugg ccauguucag acagaacacc ggcauguggg     1380

agagcaacgc caacgugaag ggcacccaga ucggcgccua cuucggcgcc agccugugca     1440

gcguggacgu ggacagcaac ggcagcaccg accuggugcu gaucggcgcc ccccacuacu     1500

acgagcagac cagaggcggc caggugagcg ugugcccccu gcccagaggc agagccagau     1560

ggcagugcga cgccgugcug uacggcgagc agggccagcc cuggggcaga uucggcgccg     1620

cccugaccgu gcugggcgac gugaacggcg acaagcugac cgacguggcc aucggcgccc     1680

ccggcgagga ggacaacaga ggcgccgugu accuguucca cggcaccagc ggcagcggca     1740

ucagccccag ccacagccag agaaucgccg gcagcaagcu gagccccaga cugcaguacu     1800

ucggccagag ccugagcggc ggccaggacc ugaccaugga cggccuggug gaccugaccg     1860

ugggcgccca gggccacgug cugcugcuga gaagccagcc cgugcugaga gugaaggcca     1920

ucauggaguu caaccccaga gagguggcca gaaacguguu cgagugcaac gaccaggugg     1980

ugaagggcaa ggaggccggc gaggugagag ugugccugca cgugcagaag agcaccagag     2040

acagacugag agagggccag auccagagcg uggugaccua cgaccuggcc cuggacagcg     2100

gcagacccca cagcagagcc guguucaacg agaccaagaa cagcaccaga agacagaccc     2160

aggugcuggg ccugacccag accugcgaga cccugaagcu gcagcugccc aacugcaucg     2220

aggaccccgu gagccccauc gugcugagac ugaacuucag ccuggugggc accccccuga     2280

gcgccuucgg caaccugaga cccgugcugg ccgaggacgc ccagagacug uucaccgccc     2340

uguuccccuu cgagaagaac ugcggcaacg acaacaucug ccaggacgac cugagcauca     2400

ccuucagcuu caugagccug gacugccugg uggugggcgg ccccagagag uucaacguga     2460

ccgugaccgu gagaaacgac ggcgaggaca gcuacagaac ccaggugacc uucuucuucc     2520

cccuggaccu gagcuacaga aaggugagca cccugcagaa ccagagaagc cagagaagcu     2580

ggagacuggc cugcgagagc gccagcagca ccgaggugag cggcgcccug aagagcacca     2640

gcugcagcau caaccacccc aucuuccccg agaacagcga ggugaccuuc aacaucaccu     2700

ucgacgugga cagcaaggcc agccugggca acaagcugcu gcugaaggcc aacgugacca     2760

gcgagaacaa caugcccaga accaacaaga ccgaguucca gcuggagcug cccgugaagu     2820

acgccgugua caugguggug accagccacg gcgugagcac caaguaccug aacuucaccg     2880

ccagcgagaa caccagcaga gugaugcagc accaguacca ggugagcaac cugggccaga     2940

gaagccugcc caucagccug guguuccugg ugcccgugag acugaaccag accgugaucu     3000

gggacagacc ccaggugacc uucagcgaga accugagcag caccugccac accaaggaga     3060

gacugcccag ccacagcgac uuccuggccg agcugagaaa ggcccccgug gugaacugca     3120

gcaucgccgu gugccagaga auccagugcg acauccccuu cuucggcauc caggaggagu     3180

ucaacgccac ccugaagggc aaccugagcu ucgacuggua caucaagacc agccacaacc     3240

accugcugau cgugagcacc gccgagaucc uguucaacga cagcguguuc acccugcugc     3300

ccggccaggg cgccuucgug agaagccaga ccgagaccaa gguggagccc uucgaggugc     3360

ccaacccccu gccccugauc gugggcagca gcgugggcgg ccugcugcug cuggcccuga     3420

ucaccgccgc ccuguacaag cugggcuucu ucaagagaca guacaaggac augaugagcg     3480

agggcggccc ccccggcgcc gagccccagu gaggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  3041
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt4)

<400>  3041
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguuca       60

gccugaagac ccugcccuuc cugcugcugc ugcacgugca gaucagcaag gccuuccccg      120

ugagcagcaa ggagaagaac accaagaccg ugcaggacua ccuggagaag uucuaccagc      180

ugcccagcaa ccaguaccag agcaccagaa agaacggcac caacgugauc guggagaagc      240

ugaaggagau gcagagauuc uucggccuga acgugaccgg caagcccaac gaggagaccc      300

uggacaugau gaagaagccc agaugcggcg ugcccgacag cggcggcuuc augcugaccc      360

ccggcaaccc caagugggag agaaccaacc ugaccuacag aaucagaaac uacacccccc      420

agcugagcga ggccgaggug gagagagcca ucaaggacgc cuucgagcug uggagcgugg      480

ccagcccccu gaucuucacc agaaucagcc agggcgaggc cgacaucaac aucgccuucu      540

accagagaga ccacggcgac aacagccccu ucgacggccc caacggcauc cuggcccacg      600

ccuuccagcc cggccagggc aucggcggcg acgcccacuu cgacgccgag gagaccugga      660

ccaacaccag cgccaacuac aaccuguucc ugguggccgc ccacgaguuc ggccacagcc      720

ugggccuggc ccacagcagc gaccccggcg cccugaugua ccccaacuac gccuucagag      780

agaccagcaa cuacagccug ccccaggacg acaucgacgg cauccaggcc aucuacggcc      840

ugagcagcaa ccccauccag cccaccggcc ccagcacccc caagcccugc gaccccagcc      900

ugaccuucga cgccaucacc acccugagag gcgagauccu guucuucaag gacagauacu      960

ucuggagaag acacccccag cugcagagag uggagaugaa cuucaucagc cuguucuggc     1020

ccagccugcc caccggcauc caggccgccu acgaggacuu cgacagagac cugaucuucc     1080

uguucaaggg caaccaguac ugggcccuga gcggcuacga cauccugcag ggcuacccca     1140

aggacaucag caacuacggc uuccccagca gcgugcaggc caucgacgcc gccguguucu     1200

acagaagcaa gaccuacuuc uucgugaacg accaguucug gagauacgac aaccagagac     1260

aguucaugga gcccggcuac cccaagagca ucagcggcgc cuuccccggc aucgagagca     1320

agguggacgc cguguuccag caggagcacu ucuuccacgu guucagcggc cccagauacu     1380

acgccuucga ccugaucgcc cagagaguga ccagaguggc cagaggcaac aaguggcuga     1440

acugcagaua cggcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  3042
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt4)

<400>  3042
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

uguggcagcc ccuggugcug gugcugcugg ugcugggcug cugcuucgcc gcccccagac      120

agagacagag cacccuggug cuguuccccg gcgaccugag aaccaaccug accgacagac      180

agcuggccga ggaguaccug uacagauacg gcuacaccag aguggccgag augagaggcg      240

agagcaagag ccugggcccc gcccugcugc ugcugcagaa gcagcugagc cugcccgaga      300

ccggcgagcu ggacagcgcc acccugaagg ccaugagaac ccccagaugc ggcgugcccg      360

accugggcag auuccagacc uucgagggcg accugaagug gcaccaccac aacaucaccu      420

acuggaucca gaacuacagc gaggaccugc ccagagccgu gaucgacgac gccuucgcca      480

gagccuucgc ccuguggagc gccgugaccc cccugaccuu caccagagug uacagcagag      540

acgccgacau cgugauccag uucggcgugg ccgagcacgg cgacggcuac cccuucgacg      600

gcaaggacgg ccugcuggcc cacgccuucc cccccggccc cggcauccag ggcgacgccc      660

acuucgacga cgacgagcug uggagccugg gcaagggcgu gguggugccc accagauucg      720

gcaacgccga cggcgccgcc ugccacuucc ccuucaucuu cgagggcaga agcuacagcg      780

ccugcaccac cgacggcaga agcgacggcc ugcccuggug cagcaccacc gccaacuacg      840

acaccgacga cagauucggc uucugcccca gcgagagacu guacacccag gacggcaacg      900

ccgacggcaa gcccugccag uuccccuuca ucuuccaggg ccagagcuac agcgccugca      960

ccaccgacgg cagaagcgac ggcuacagau ggugcgccac caccgccaac uacgacagag     1020

acaagcuguu cggcuucugc cccaccagag ccgacagcac cgugaugggc ggcaacagcg     1080

ccggcgagcu gugcguguuc cccuucaccu uccugggcaa ggaguacagc accugcacca     1140

gcgagggcag aggcgacggc agacuguggu gcgccaccac cagcaacuuc gacagcgaca     1200

agaagugggg cuucugcccc gaccagggcu acagccuguu ccugguggcc gcccacgagu     1260

ucggccacgc ccugggccug gaccacagca gcgugcccga ggcccugaug uaccccaugu     1320

acagauucac cgagggcccc ccccugcaca aggacgacgu gaacggcauc agacaccugu     1380

acggccccag acccgagccc gagcccagac cccccaccac caccaccccc cagcccaccg     1440

ccccccccac cgugugcccc accggccccc ccaccgugca ccccagcgag agacccaccg     1500

ccggccccac cggccccccc agcgccggcc ccaccggccc ccccaccgcc ggccccagca     1560

ccgccaccac cgugccccug agccccgugg acgacgccug caacgugaac aucuucgacg     1620

ccaucgccga gaucggcaac cagcuguacc uguucaagga cggcaaguac uggagauuca     1680

gcgagggcag aggcagcaga ccccagggcc ccuuccugau cgccgacaag uggcccgccc     1740

ugcccagaaa gcuggacagc guguucgagg agagacugag caagaagcug uucuucuuca     1800

gcggcagaca ggugugggug uacaccggcg ccagcgugcu gggccccaga agacuggaca     1860

agcugggccu gggcgccgac guggcccagg ugaccggcgc ccugagaagc ggcagaggca     1920

agaugcugcu guucagcggc agaagacugu ggagauucga cgugaaggcc cagauggugg     1980

accccagaag cgccagcgag guggacagaa uguuccccgg cgugccccug gacacccacg     2040

acguguucca guacagagag aaggccuacu ucugccagga cagauucuac uggagaguga     2100

gcagcagaag cgagcugaac cagguggacc aggugggcua cgugaccuac gacauccugc     2160

agugccccga ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  3043
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt4)

<400>  3043
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ccggcgugcu ggccgccuuc cuguuccuga gcuggaccca cugcagagcc cugccccugc      120

ccagcggcgg cgacgaggac gaccugagcg aggaggaccu gcaguucgcc gagagauacc      180

ugagaagcua cuaccacccc accaaccugg ccggcauccu gaaggagaac gccgccagca      240

gcaugaccga gagacugaga gagaugcaga gcuucuucgg ccuggaggug accggcaagc      300

uggacgacaa cacccuggac gugaugaaga agcccagaug cggcgugccc gacgugggcg      360

aguacaacgu guuccccaga acccugaagu ggagcaagau gaaccugacc uacagaaucg      420

ugaacuacac ccccgacaug acccacagcg agguggagaa ggccuucaag aaggccuuca      480

agguguggag cgacgugacc ccccugaacu ucaccagacu gcacgacggc aucgccgaca      540

ucaugaucag cuucggcauc aaggagcacg gcgacuucua ccccuucgac ggccccagcg      600

gccugcuggc ccacgccuuc ccccccggcc ccaacuacgg cggcgacgcc cacuucgacg      660

acgacgagac cuggaccagc agcagcaagg gcuacaaccu guuccuggug gccgcccacg      720

aguucggcca cagccugggc cuggaccaca gcaaggaccc cggcgcccug auguucccca      780

ucuacaccua caccggcaag agccacuuca ugcugcccga cgacgacgug cagggcaucc      840

agagccugua cggccccggc gacgaggacc ccaaccccaa gcaccccaag acccccgaca      900

agugcgaccc cagccugagc cuggacgcca ucaccagccu gagaggcgag accaugaucu      960

ucaaggacag auucuucugg agacugcacc cccagcaggu ggacgccgag cuguuccuga     1020

ccaagagcuu cuggcccgag cugcccaaca gaaucgacgc cgccuacgag caccccagcc     1080

acgaccugau cuucaucuuc agaggcagaa aguucugggc ccugaacggc uacgacaucc     1140

uggagggcua ccccaagaag aucagcgagc ugggccugcc caaggaggug aagaagauca     1200

gcgccgccgu gcacuucgag gacaccggca agacccugcu guucagcggc aaccaggugu     1260

ggagauacga cgacaccaac cacaucaugg acaaggacua ccccagacug aucgaggagg     1320

acuuccccgg caucggcgac aagguggacg ccguguacga gaagaacggc uacaucuacu     1380

ucuucaacgg ccccauccag uucgaguaca gcaucuggag caacagaauc gugagaguga     1440

ugcccgccaa cagcauccug uggugcugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3044
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt4)

<400>  3044
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

cccccaacac caccgaggac uacgacacca ccaccgaguu cgacuacggc gacgccaccc      120

ccugccagaa ggugaacgag agagccuucg gcgcccagcu gcugcccccc cuguacagcc      180

ugguguucgu gaucggccug gugggcaaca uccugguggu gcuggugcug gugcaguaca      240

agagacugaa gaacaugacc agcaucuacc ugcugaaccu ggccaucagc gaccugcugu      300

uccuguucac ccugcccuuc uggaucgacu acaagcugaa ggacgacugg guguucggcg      360

acgccaugug caagauccug agcggcuucu acuacaccgg ccuguacagc gagaucuucu      420

ucaucauccu gcugaccauc gacagauacc uggccaucgu gcacgccgug uucgcccuga      480

gagccagaac cgugaccuuc ggcgugauca ccagcaucau caucugggcc cuggccaucc      540

uggccagcau gcccggccug uacuucagca agacccagug ggaguucacc caccacaccu      600

gcagccugca cuucccccac gagagccuga gagaguggaa gcuguuccag gcccugaagc      660

ugaaccuguu cggccuggug cugccccugc uggugaugau caucugcuac accggcauca      720

ucaagauccu gcugagaaga cccaacgaga agaagagcaa ggccgugaga cugaucuucg      780

ugaucaugau caucuucuuc cuguucugga cccccuacaa ccugaccauc cugaucagcg      840

uguuccagga cuuccuguuc acccacgagu gcgagcagag cagacaccug gaccuggccg      900

ugcaggugac cgaggugauc gccuacaccc acugcugcgu gaaccccgug aucuacgccu      960

ucgugggcga gagauucaga aaguaccuga gacagcuguu ccacagaaga guggccgugc     1020

accuggugaa guggcugccc uuccugagcg uggacagacu ggagagagug agcagcacca     1080

gccccagcac cggcgagcac gagcugagcg ccggcuucug aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  3045
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt4)

<400>  3045
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagaa       60

cccuggccug ccugcugcug cugggcugcg gcuaccuggc ccacgugcug gccgaggagg      120

ccgagauccc cagagaggug aucgagagac uggccagaag ccagauccac agcaucagag      180

accugcagag acugcuggag aucgacagcg ugggcagcga ggacagccug gacaccagcc      240

ugagagccca cggcgugcac gccaccaagc acgugcccga gaagagaccc cugcccauca      300

gaagaaagag aagcaucgag gaggccgugc ccgccgugug caagaccaga accgugaucu      360

acgagauccc cagaagccag guggacccca ccagcgccaa cuuccugauc uggccccccu      420

gcguggaggu gaagagaugc accggcugcu gcaacaccag cagcgugaag ugccagccca      480

gcagagugca ccacagaagc gugaaggugg ccaaggugga guacgugaga aagaagccca      540

agcugaagga ggugcaggug agacuggagg agcaccugga gugcgccugc gccaccacca      600

gccugaaccc cgacuacaga gaggaggaca ccggcagacc cagagagagc ggcaagaaga      660

gaaagagaaa gagacugaag cccaccugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  3046
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt4)

<400>  3046
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaca       60

gaugcugggc ccuguuccug agccugugcu gcuaccugag acuggugagc gccgagggcg      120

accccauccc cgaggagcug uacgagaugc ugagcgacca cagcaucaga agcuucgacg      180

accugcagag acugcugcac ggcgaccccg gcgaggagga cggcgccgag cuggaccuga      240

acaugaccag aagccacagc ggcggcgagc uggagagccu ggccagaggc agaagaagcc      300

ugggcagccu gaccaucgcc gagcccgcca ugaucgccga gugcaagacc agaaccgagg      360

uguucgagau cagcagaaga cugaucgaca gaaccaacgc caacuuccug guguggcccc      420

ccugcgugga ggugcagaga ugcagcggcu gcugcaacaa cagaaacgug cagugcagac      480

ccacccaggu gcagcugaga cccgugcagg ugagaaagau cgagaucgug agaaagaagc      540

ccaucuucaa gaaggccacc gugacccugg aggaccaccu ggccugcaag ugcgagaccg      600

uggccgccgc cagacccgug accagaagcc ccggcggcag ccaggagcag agagccaaga      660

ccccccagac cagagugacc aucagaaccg ugagagugag aagacccccc aagggcaagc      720

acagaaaguu caagcacacc cacgacaaga ccgcccugaa ggagacccug ggcgccugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  3047
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt4)

<400>  3047
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

uguucggccu gcugcugcug accagcgccc uggccggcca gagacagggc acccaggccg      120

agagcaaccu gagcagcaag uuccaguuca gcagcaacaa ggagcagaac ggcgugcagg      180

acccccagca cgagagaauc aucaccguga gcaccaacgg cagcauccac agccccagau      240

ucccccacac cuaccccaga aacaccgugc ugguguggag acugguggcc guggaggaga      300

acguguggau ccagcugacc uucgacgaga gauucggccu ggaggacccc gaggacgaca      360

ucugcaagua cgacuucgug gagguggagg agcccagcga cggcaccauc cugggcagau      420

ggugcggcag cggcaccgug cccggcaagc agaucagcaa gggcaaccag aucagaauca      480

gauucgugag cgacgaguac uuccccagcg agcccggcuu cugcauccac uacaacaucg      540

ugaugcccca guucaccgag gccgugagcc ccagcgugcu gccccccagc gcccugcccc      600

uggaccugcu gaacaacgcc aucaccgccu ucagcacccu ggaggaccug aucagauacc      660

uggagcccga gagauggcag cuggaccugg aggaccugua cagacccacc uggcagcugc      720

ugggcaaggc cuucguguuc ggcagaaaga gcagaguggu ggaccugaac cugcugaccg      780

aggaggugag acuguacagc ugcaccccca gaaacuucag cgugagcauc agagaggagc      840

ugaagagaac cgacaccauc uucuggcccg gcugccugcu ggugaagaga ugcggcggca      900

acugcgccug cugccugcac aacugcaacg agugccagug cgugcccagc aaggugacca      960

agaaguacca cgaggugcug cagcugagac ccaagaccgg cgugagaggc cugcacaaga     1020

gccugaccga cguggcccug gagcaccacg aggagugcga cugcgugugc agaggcagca     1080

ccggcggcug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  3048
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt4)

<400>  3048
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gacugaucuu cguguacacc cugaucugcg ccaacuucug cagcugcaga gacaccagcg      120

ccacccccca gagcgccagc aucaaggccc ugagaaacgc caaccugaga agagacgacc      180

uguacagaag agacgagacc auccagguga agggcaacgg cuacgugcag agccccagau      240

uccccaacag cuaccccaga aaccugcugc ugaccuggag acugcacagc caggagaaca      300

ccagaaucca gcugguguuc gacaaccagu ucggccugga ggaggccgag aacgacaucu      360

gcagauacga cuucguggag guggaggaca ucagcgagac cagcaccauc aucagaggca      420

gauggugcgg ccacaaggag gugcccccca gaaucaagag cagaaccaac cagaucaaga      480

ucaccuucaa gagcgacgac uacuucgugg ccaagcccgg cuucaagauc uacuacagcc      540

ugcuggagga cuuccagccc gccgccgcca gcgagaccaa cugggagagc gugaccagca      600

gcaucagcgg cgugagcuac aacagcccca gcgugaccga ccccacccug aucgccgacg      660

cccuggacaa gaagaucgcc gaguucgaca ccguggagga ccugcugaag uacuucaacc      720

ccgagagcug gcaggaggac cuggagaaca uguaccugga cacccccaga uacagaggca      780

gaagcuacca cgacagaaag agcaaggugg accuggacag acugaacgac gacgccaaga      840

gauacagcug cacccccaga aacuacagcg ugaacaucag agaggagcug aagcuggcca      900

acgugguguu cuuccccaga ugccugcugg ugcagagaug cggcggcaac ugcggcugcg      960

gcaccgugaa cuggagaagc ugcaccugca acagcggcaa gaccgugaag aaguaccacg     1020

aggugcugca guucgagccc ggccacauca agagaagagg cagagccaag accauggccc     1080

ugguggacau ccagcuggac caccacgaga gaugcgacug caucugcagc agcagacccc     1140

ccagaugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  3049
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt4)

<400>  3049
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguga       60

cccacagcaa guuccccgcc gccggcauga gcagaccccu ggacaccagc cugagacuga      120

agaccuucag cagcaagagc gaguaccagc ugguggugaa cgccgugaga aagcugcagg      180

agagcggcuu cuacuggagc gccgugaccg gcggcgaggc caaccugcug cugagcgccg      240

agcccgccgg caccuuccug aucagagaca gcagcgacca gagacacuuc uucacccuga      300

gcgugaagac ccagagcggc accaagaacc ugagaaucca gugcgagggc ggcagcuuca      360

gccugcagag cgaccccaga agcacccagc ccgugcccag auucgacugc gugcugaagc      420

uggugcacca cuacaugccc ccccccggcg cccccagcuu ccccagcccc cccaccgagc      480

ccagcagcga ggugcccgag cagcccagcg cccagccccu gcccggcagc ccccccagaa      540

gagccuacua caucuacagc ggcggcgaga agaucccccu ggugcugagc agaccccuga      600

gcagcaacgu ggccacccug cagcaccugu gcagaaagac cgugaacggc caccuggaca      660

gcuacgagaa ggugacccag cugcccggcc ccaucagaga guuccuggac caguacgacg      720

ccccccugug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  3050
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt4)

<400>  3050
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugc       60

ccagcgccgg ccagcuggcc cuguucgccc ugggcaucgu gcuggccgcc ugccaggccc      120

uggagaacag caccagcccc cugagcgccg acccccccgu ggccgccgcc guggugagcc      180

acuucaacga cugccccgac agccacaccc aguucugcuu ccacggcacc ugcagauucc      240

uggugcagga ggacaagccc gccugcgugu gccacagcgg cuacgugggc gccagaugcg      300

agcacgccga ccugcuggcc gugguggccg ccagccagaa gaagcaggcc aucaccgccc      360

uggugguggu gagcaucgug gcccuggccg ugcugaucau caccugcgug cugauccacu      420

gcugccaggu gagaaagcac ugcgaguggu gcagagcccu gaucugcaga cacgagaagc      480

ccagcgcccu gcugaagggc agaaccgccu gcugccacag cgagaccgug gugugaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  3051
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt4)

<400>  3051
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ccagcggccu gagacugcug ccccugcugc ugccccugcu guggcugcug gugcugaccc      120

ccggcagacc cgccgccggc cugagcaccu gcaagaccau cgacauggag cuggugaaga      180

gaaagagaau cgaggccauc agaggccaga uccugagcaa gcugagacug gccagccccc      240

ccagccaggg cgaggugccc cccggccccc ugcccgaggc cgugcuggcc cuguacaaca      300

gcaccagaga cagaguggcc ggcgagagcg ccgagcccga gcccgagccc gaggccgacu      360

acuacgccaa ggaggugacc agagugcuga ugguggagac ccacaacgag aucuacgaca      420

aguucaagca gagcacccac agcaucuaca uguucuucaa caccagcgag cugagagagg      480

ccgugcccga gcccgugcug cugagcagag ccgagcugag acugcugaga cugaagcuga      540

agguggagca gcacguggag cuguaccaga aguacagcaa caacagcugg agauaccuga      600

gcaacagacu gcuggccccc agcgacagcc ccgaguggcu gagcuucgac gugaccggcg      660

uggugagaca guggcugagc agaggcggcg agaucgaggg cuucagacug agcgcccacu      720

gcagcugcga cagcagagac aacacccugc agguggacau caacggcuuc accaccggca      780

gaagaggcga ccuggccacc auccacggca ugaacagacc cuuccugcug cugauggcca      840

ccccccugga gagagcccag caccugcaga gcagcagaca cagaagagcc cuggacacca      900

acuacugcuu cagcagcacc gagaagaacu gcugcgugag acagcuguac aucgacuuca      960

gaaaggaccu gggcuggaag uggauccacg agcccaaggg cuaccacgcc aacuucugcc     1020

ugggccccug ccccuacauc uggagccugg acacccagua cagcaaggug cuggcccugu     1080

acaaccagca caaccccggc gccagcgccg cccccugcug cgugccccag gcccuggagc     1140

cccugcccau cguguacuac gugggcagaa agcccaaggu ggagcagcug agcaacauga     1200

ucgugagaag cugcaagugc agcugaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  3052
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt4)

<400>  3052
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugcgugcu gagcgccuuc cugauccugc accuggugac cguggcccug agccugagca      120

ccugcagcac ccuggacaug gaccaguuca ugagaaagag aaucgaggcc aucagaggcc      180

agauccugag caagcugaag cugaccagcc cccccgagga cuaccccgag cccgaggagg      240

ugccccccga ggugaucagc aucuacaaca gcaccagaga ccugcugcag gagaaggcca      300

gcagaagagc cgccgccugc gagagagaga gaagcgacga ggaguacuac gccaaggagg      360

uguacaagau cgacaugccc cccuucuucc ccagcgagaa cgccaucccc cccaccuucu      420

acagacccua cuucagaauc gugagauucg acgugagcgc cauggagaag aacgccagca      480

accuggugaa ggccgaguuc agaguguuca gacugcagaa ccccaaggcc agagugcccg      540

agcagagaau cgagcuguac cagauccuga agagcaagga ccugaccagc cccacccaga      600

gauacaucga cagcaaggug gugaagacca gagccgaggg cgaguggcug agcuucgacg      660

ugaccgacgc cgugcacgag uggcugcacc acaaggacag aaaccugggc uucaagauca      720

gccugcacug ccccugcugc accuucgugc ccagcaacaa cuacaucauc cccaacaaga      780

gcgaggagcu ggaggccaga uucgccggca ucgacggcac cagcaccuac accagcggcg      840

accagaagac caucaagagc accagaaaga agaacagcgg caagaccccc caccugcugc      900

ugaugcugcu gcccagcuac agacuggaga gccagcagac caacagaaga aagaagagag      960

cccuggacgc cgccuacugc uucagaaacg ugcaggacaa cugcugccug agaccccugu     1020

acaucgacuu caagagagac cugggcugga aguggaucca cgagcccaag ggcuacaacg     1080

ccaacuucug cgccggcgcc ugccccuacc uguggagcag cgacacccag cacagcagag     1140

ugcugagccu guacaacacc aucaaccccg aggccagcgc cagccccugc ugcgugagcc     1200

aggaccugga gccccugacc auccuguacu acaucggcaa gacccccaag aucgagcagc     1260

ugagcaacau gaucgugaag agcugcaagu gcagcugagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  3053
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt4)

<400>  3053
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

ugcaccugca gagagcccug guggugcugg cccugcugaa cuucgccacc gugagccuga      120

gccugagcac cugcaccacc cuggacuucg gccacaucaa gaagaagaga guggaggcca      180

ucagaggcca gauccugagc aagcugagac ugaccagccc ccccgagccc accgugauga      240

cccacgugcc cuaccaggug cuggcccugu acaacagcac cagagagcug cuggaggaga      300

ugcacggcga gagagaggag ggcugcaccc aggagaacac cgagagcgag uacuacgcca      360

aggagaucca caaguucgac augauccagg gccuggccga gcacaacgag cuggccgugu      420

gccccaaggg caucaccagc aagguguuca gauucaacgu gagcagcgug gagaagaaca      480

gaaccaaccu guucagagcc gaguucagag ugcugagagu gcccaacccc agcagcaaga      540

gaaacgagca gagaaucgag cuguuccaga uccugagacc cgacgagcac aucgccaagc      600

agagauacau cggcggcaag aaccugccca ccagaggcac cgccgagugg cugagcuucg      660

acgugaccga caccgugaga gaguggcugc ugagaagaga gagcaaccug ggccuggaga      720

ucagcaucca cugccccugc cacaccuucc agcccaacgg cgacauccug gagaacaucc      780

acgaggugau ggagaucaag uucaagggcg uggacaacga ggacgaccac ggcagaggcg      840

accugggcag acugaagaag cagaaggacc accacaaccc ccaccugauc cugaugauga      900

ucccccccca cagacuggac aaccccggcc agggcggcca gagaaagaag agagcccugg      960

acaccaacua cugcuucaga aaccuggagg agaacugcug cgugagaccc cuguacaucg     1020

acuucagaca ggaccugggc uggaaguggg ugcacgagcc caagggcuac uacgccaacu     1080

ucugcagcgg ccccugcccc uaccugagaa gcgccgacac cacccacagc accgugcugg     1140

gccuguacaa cacccugaac cccgaggcca gcgccagccc cugcugcgug ccccaggacc     1200

uggagccccu gaccauccug uacuacgugg gcagaacccc caagguggag cagcugagca     1260

acaugguggu gaagagcugc aagugcagcu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3054
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt4)

<400>  3054
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ccguggccgu gugggccgcc cuggccgugg gccuggagcu gugggccgcc gcccacgccc      120

ugcccgccca gguggccuuc acccccuacg cccccgagcc cggcagcacc ugcagacuga      180

gagaguacua cgaccagacc gcccagaugu gcugcagcaa gugcagcccc ggccagcacg      240

ccaagguguu cugcaccaag accagcgaca ccgugugcga cagcugcgag gacagcaccu      300

acacccagcu guggaacugg gugcccgagu gccugagcug cggcagcaga ugcagcagcg      360

accaggugga gacccaggcc ugcaccagag agcagaacag aaucugcacc ugcagacccg      420

gcugguacug cgcccugagc aagcaggagg gcugcagacu gugcgccccc cugagaaagu      480

gcagacccgg cuucggcgug gccagacccg gcaccgagac cagcgacgug gugugcaagc      540

ccugcgcccc cggcaccuuc agcaacacca ccagcagcac cgacaucugc agaccccacc      600

agaucugcaa cgugguggcc auccccggca acgccagcau ggacgccgug ugcaccagca      660

ccagccccac cagaagcaug gcccccggcg ccgugcaccu gccccagccc gugagcacca      720

gaagccagca cacccagccc acccccgagc ccagcaccgc ccccagcacc agcuuccugc      780

ugcccauggg ccccagcccc cccgccgagg gcagcaccgg cgacuucgcc cugcccgugg      840

gccugaucgu gggcgugacc gcccugggcc ugcugaucau cggcguggug aacugcguga      900

ucaugaccca ggugaagaag aagccccugu gccugcagag agaggccaag gugccccacc      960

ugcccgccga caaggccaga ggcacccagg gccccgagca gcagcaccug cugaucaccg     1020

cccccagcag cagcagcagc agccuggaga gcagcgccag cgcccuggac agaagagccc     1080

ccaccagaaa ccagccccag gcccccggcg uggaggccag cggcgccggc gaggccagag     1140

ccagcaccgg cagcagcgac agcagccccg gcggccacgg cacccaggug aacgugaccu     1200

gcaucgugaa cgugugcagc agcagcgacc acagcagcca gugcagcagc caggccagca     1260

gcaccauggg cgacaccgac agcagcccca gcgagagccc caaggacgag caggugcccu     1320

ucagcaagga ggagugcgcc uucagaagcc agcuggagac ccccgagacc cugcugggca     1380

gcaccgagga gaagccccug ccccugggcg ugcccgacgc cggcaugaag cccagcugag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  3055
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt4)

<400>  3055
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

ugaugagacu guuccccugc uuccugcagc ugcuggccgg ccuggcccug cccgccgugc      120

ccccccagca gugggcccug agcgccggca acggcagcag cgagguggag guggugcccu      180

uccaggaggu guggggcaga agcuacugca gagcccugga gagacuggug gacgugguga      240

gcgaguaccc cagcgaggug gagcacaugu ucagccccag cugcgugagc cugcugagau      300

gcaccggcug cugcggcgac gagaaccugc acugcgugcc cguggagacc gccaacguga      360

ccaugcagcu gcugaagauc agaagcggcg acagacccag cuacguggag cugaccuuca      420

gccagcacgu gagaugcgag ugcagacccc ugagagagaa gaugaagccc gagagaagaa      480

gacccaaggg cagaggcaag agaagaagag agaagcagag acccaccgac ugccaccugu      540

gcggcgacgc cgugcccaga agaugaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  3056
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt4)

<400>  3056
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

acagacagac cgacaccgcc cccagcccca gcuaccaccu gcugcccggc agaagaagaa      120

ccguggacgc cgccgccagc agaggccagg gccccgagcc cgcccccggc ggcggcgugg      180

agggcguggg cgccagaggc guggcccuga agcuguucgu gcagcugcug ggcugcagca      240

gauucggcgg cgccguggug agagccggcg aggccgagcc cagcggcgcc gccagaagcg      300

ccagcagcgg cagagaggag ccccagcccg aggagggcga ggaggaggag gagaaggagg      360

aggagagagg cccccagugg agacugggcg ccagaaagcc cggcagcugg accggcgagg      420

ccgccgugug cgccgacagc gcccccgccg ccagagcccc ccaggcccug gccagagcca      480

gcggcagagg cggcagagug gccagaagag gcgccgagga gagcggcccc ccccacagcc      540

ccagcagaag aggcagcgcc agcagagccg gccccggcag agccagcgag accaugaacu      600

uccugcugag cugggugcac uggagccugg cccugcugcu guaccugcac cacgccaagu      660

ggagccaggc cgcccccaug gccgagggcg gcggccagaa ccaccacgag guggugaagu      720

ucauggacgu guaccagaga agcuacugcc accccaucga gacccuggug gacaucuucc      780

aggaguaccc cgacgagauc gaguacaucu ucaagcccag cugcgugccc cugaugagau      840

gcggcggcug cugcaacgac gagggccugg agugcgugcc caccgaggag agcaacauca      900

ccaugcagau caugagaauc aagccccacc agggccagca caucggcgag augagcuucc      960

ugcagcacaa caagugcgag ugcagaccca agaaggacag agccagacag gagaagaaga     1020

gcgugagagg caagggcaag ggccagaaga gaaagagaaa gaagagcaga uacaagagcu     1080

ggagcgugua cgugggcgcc agaugcugcc ugaugcccug gagccugccc ggcccccacc     1140

ccugcggccc cugcagcgag agaagaaagc accuguucgu gcaggacccc cagaccugca     1200

agugcagcug caagaacacc gacagcagau gcaaggccag acagcuggag cugaacgaga     1260

gaaccugcag augcgacaag cccagaagau gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3057
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt4)

<400>  3057
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugcugag cugggugcac uggagccugg cccugcugcu guaccugcac cacgccaagu      120

ggagccaggc cgcccccaug gccgagggcg gcggccagaa ccaccacgag guggugaagu      180

ucauggacgu guaccagaga agcuacugcc accccaucga gacccuggug gacaucuucc      240

aggaguaccc cgacgagauc gaguacaucu ucaagcccag cugcgugccc cugaugagau      300

gcggcggcug cugcaacgac gagggccugg agugcgugcc caccgaggag agcaacauca      360

ccaugcagau caugagaauc aagccccacc agggccagca caucggcgag augagcuucc      420

ugcagcacaa caagugcgag ugcagaccca agaaggacag agccagacag gagaagaaga      480

gcgugagagg caagggcaag ggccagaaga gaaagagaaa gaagagcaga uacaagagcu      540

ggagcgugua cgugggcgcc agaugcugcc ugaugcccug gagccugccc ggcccccacc      600

ccugcggccc cugcagcgag agaagaaagc accuguucgu gcaggacccc cagaccugca      660

agugcagcug caagaacacc gacagcagau gcaaggccag acagcuggag cugaacgaga      720

gaaccugcag augcgacaag cccagaagau gaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  3058
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt4)

<400>  3058
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

cccugcugag aagacugcug cuggccgccc ugcugcagcu ggcccccgcc caggcccccg      120

ugagccagcc cgacgccccc ggccaccaga gaaagguggu gagcuggauc gacguguaca      180

ccagagccac cugccagccc agagaggugg uggugccccu gaccguggag cugaugggca      240

ccguggccaa gcagcuggug cccagcugcg ugaccgugca gagaugcggc ggcugcugcc      300

ccgacgacgg ccuggagugc gugcccaccg gccagcacca ggugagaaug cagauccuga      360

ugaucagaua ccccagcagc cagcugggcg agaugagccu ggaggagcac agccagugcg      420

agugcagacc caagaagaag gacagcgccg ugaagcccga cagagccgcc accccccacc      480

acagacccca gcccagaagc gugcccggcu gggacagcgc ccccggcgcc cccagccccg      540

ccgacaucac ccaccccacc cccgcccccg gccccagcgc ccacgccgcc cccagcacca      600

ccagcgcccu gacccccggc cccgccgccg ccgccgccga cgccgccgcc agcagcgugg      660

ccaagggcgg cgccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  3059
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt4)

<400>  3059
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ugcugggcuu cuucagcgug gccugcagcc ugcuggccgc cgcccugcug cccggcccca      120

gagaggcccc cgccgccgcc gccgccuucg agagcggccu ggaccugagc gacgccgagc      180

ccgacgccgg cgaggccacc gccuacgcca gcaaggaccu ggaggagcag cugagaagcg      240

ugagcagcgu ggacgagcug augaccgugc uguaccccga guacuggaag auguacaagu      300

gccagcugag aaagggcggc uggcagcaca acagagagca ggccaaccug aacagcagaa      360

ccgaggagac caucaaguuc gccgccgccc acuacaacac cgagauccug aagagcaucg      420

acaacgagug gagaaagacc cagugcaugc ccagagaggu gugcaucgac gugggcaagg      480

aguucggcgu ggccaccaac accuucuuca agccccccug cgugagcgug uacagaugcg      540

gcggcugcug caacagcgag ggccugcagu gcaugaacac cagcaccagc uaccugagca      600

agacccuguu cgagaucacc gugccccuga gccagggccc caagcccgug accaucagcu      660

ucgccaacca caccagcugc agaugcauga gcaagcugga cguguacaga caggugcaca      720

gcaucaucag aagaagccug cccgccaccc ugccccagug ccaggccgcc aacaagaccu      780

gccccaccaa cuacaugugg aacaaccaca ucugcagaug ccuggcccag gaggacuuca      840

uguucagcag cgacgccggc gacgacagca ccgacggcuu ccacgacauc ugcggcccca      900

acaaggagcu ggacgaggag accugccagu gcgugugcag agccggccug agacccgcca      960

gcugcggccc ccacaaggag cuggacagaa acagcugcca gugcgugugc aagaacaagc     1020

uguuccccag ccagugcggc gccaacagag aguucgacga gaacaccugc cagugcgugu     1080

gcaagagaac cugccccaga aaccagcccc ugaaccccgg caagugcgcc ugcgagugca     1140

ccgagagccc ccagaagugc cugcugaagg gcaagaaguu ccaccaccag accugcagcu     1200

gcuacagaag acccugcacc aacagacaga aggccugcga gcccggcuuc agcuacagcg     1260

aggaggugug cagaugcgug cccagcuacu ggaagagacc ccagaugagc ugaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  3060
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt4)

<400>  3060
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguaca       60

gagagugggu gguggugaac guguucauga ugcuguacgu gcagcuggug cagggcagca      120

gcaacgagca cggccccgug aagagaagca gccagagcac ccuggagaga agcgagcagc      180

agaucagagc cgccagcagc cuggaggagc ugcugagaau cacccacagc gaggacugga      240

agcuguggag augcagacug agacugaaga gcuucaccag cauggacagc agaagcgcca      300

gccacagaag caccagauuc gccgccaccu ucuacgacau cgagacccug aaggugaucg      360

acgaggagug gcagagaacc cagugcagcc ccagagagac cugcguggag guggccagcg      420

agcugggcaa gagcaccaac accuucuuca agccccccug cgugaacgug uucagaugcg      480

gcggcugcug caacgaggag agccugaucu gcaugaacac cagcaccagc uacaucagca      540

agcagcuguu cgagaucagc gugccccuga ccagcgugcc cgagcuggug cccgugaagg      600

uggccaacca caccggcugc aagugccugc ccaccgcccc cagacacccc uacagcauca      660

ucagaagaag cauccagauc cccgaggagg acagaugcag ccacagcaag aagcugugcc      720

ccaucgacau gcugugggac agcaacaagu gcaagugcgu gcugcaggag gagaaccccc      780

uggccggcac cgaggaccac agccaccugc aggagcccgc ccugugcggc ccccacauga      840

uguucgacga ggacagaugc gagugcgugu gcaagacccc cugccccaag gaccugaucc      900

agcaccccaa gaacugcagc ugcuucgagu gcaaggagag ccuggagacc ugcugccaga      960

agcacaagcu guuccacccc gacaccugca gcugcgagga cagaugcccc uuccacacca     1020

gacccugcgc cagcggcaag accgccugcg ccaagcacug cagauucccc aaggagaaga     1080

gagccgccca gggcccccac agcagaaaga accccugagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  3061
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt5)

<400>  3061
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcgaugagac cggcuucgaa cacuccgggc uguggguguc uguccucgcc ggacugcuuc      120

ugggcgcuug ccaggcccau cccaucccug acagcucccc gcuccugcaa uuugggggac      180

agguuagaca gcgguaccuu uauacagaug acgcgcagca aacggaggcu caccuggaaa      240

uucgcgagga uggcaccgug ggcggagccg ccgaccaguc ucccgaaagc cuccugcagc      300

ugaaggcucu caaaccuggc gugauccaga uucugggcgu caagacaucc agauuccuuu      360

gucaacggcc cgauggggcc cuguacggau cucuccauuu ugacccugag gcuugcagcu      420

uccgcgagcu gcuucuggaa gauggcuaua acguguacca guccgaggcc cacgggcucc      480

cccugcaucu gccuggaaau aaaagcccgc acagagaccc cgcgccucgg ggccccgccc      540

gcuuucuccc ucugcccggg cuuccgccug cucugcccga accucccgga auccucgcuc      600

cccagccucc ggauguuggg ucuuccgacc cccugagcau ggugggcccu ucucagggga      660

gaucccccag cuaugccucu ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  3062
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt5)

<400>  3062
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuuuccccc ucugcuccug cuucuguucu ggggcguggu cucccauucu uucccggcca      120

cccucgagac acaggaacaa gacguugauc uggugcagaa guaccuugag aaauauuaca      180

accugaagaa ugacgggaga cagguggaaa aacggcgcaa cagcggaccc gucguggaga      240

agcucaaaca gaugcaagaa uuuuucggcc ugaagguuac ggggaagccu gaugcugaga      300

cccugaaagu gaugaagcag cccagaugcg gagucccuga cguggcccag uuuguucuca      360

cagagggcaa uccccggugg gaacagaccc accugacaua ucgcaucgag aacuacaccc      420

cugaucuucc gagagcggac guggaucaug cuauugaaaa agccuuccaa cuguggucca      480

augucacacc ccucaccuuu acgaaggugu cugaggggca ggccgacauc augauuagcu      540

ucgugcgggg agaucaccgc gacaacuccc cuuuugaugg ccccggcggg aaucuggcuc      600

augccuucca gccuggaccc ggcaucgggg gagacgcuca cuuugaugag gacgaaagau      660

ggaccaacaa uuuccgggag uauaaccuuc accgcgucgc cgcgcaugaa cugggccacu      720

cucucgggcu gagccauucc acagacauug gagcccugau guacccgagc uauaccuuuu      780

cuggcgaugu ucagcucgcu caagacgaua ucgacggcau ccaggccauu uacgggagau      840

cccagaaucc ugugcaaccc aucggaccuc agacacccaa ggcuugugau agcaaacuga      900

ccuucgacgc cauuacgaca auccggggcg aggugauguu cuuuaaggau cgcuucuaca      960

ugagaaccaa ccccuuuuau ccugaagucg agcuuaauuu cauuucugug uuuuggccgc     1020

agcugcccaa cgggcucgag gcggccuacg aguucgcuga ccgggaugaa guucgcuuuu     1080

ucaaaggaaa uaaguauugg gccgugcagg gccaaaacgu ccugcacggg uacccuaaag     1140

acaucuauuc cagcuuugga uuccccagaa cagugaagca cauugaugcu gcccuuucug     1200

aagagaacac cggcaaaacc uacuuuuucg uugccaauaa guauuggcgg uacgacgaau     1260

acaaaagauc cauggacccu ggcuauccca agaugaucgc ucaugauuuu ccggggaucg     1320

gacacaaggu ggacgcgguc uucaugaaag auggcuucuu uuacuucuuu caugggacac     1380

gccaguauaa guucgacccu aaaacgaagc ggauucugac ccuccagaaa gccaacagcu     1440

gguuuaauug cagaaagaac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  3063
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt5)

<400>  3063
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuuuccccc ucugcuccug cuucuguucu ggggcguggu cucccauucu uucguucuca      120

ccgaggggaa cccgagaugg gaacagacac accugacgua ccggauugag aauuauaccc      180

ccgaccuucc ucgcgccgau guggaccaug cuauugaaaa ggccuuucaa cuguggagca      240

acgugacacc ccucaccuuc acaaaagucu ccgagggaca ggcggauauc augauuucuu      300

uugugagagg cgaccaccgg gauaauagcc cuuucgacgg gcccggaggc aaccuggcuc      360

augccuuuca gccugggccg ggaaucggcg gcgaugccca cuucgacgaa gaugagcgcu      420

ggaccaauaa cuuuagagag uacaaucugc accggguugc ugcccaugaa cucgggcacu      480

cccugggacu uucucauagc acagacauug gcgcucugau guaucccucc uacaccuuca      540

gcggggaugu gcagcucgcc caagacgaua ucgacggaau ccaggcgauu uauggccgcu      600

cucagaaccc uguccagccc aucgggccuc aaacgcccaa ggccugcgac uccaaacuga      660

ccuuugaugc uauuacaacc aucagaggag aggugauguu cuuuaaggac cgguucuaca      720

ugcgcacaaa uccguucuau ccugaaguug agcuuaacuu uauuagcgug uucuggcccc      780

agcugccuaa uggccucgag gccgcuuacg aauuugccga uagagacgag guccgguucu      840

uuaaaggcaa caaguacugg gcggugcagg ggcagaaugu gcugcacgga uaucccaagg      900

auaucuacuc uuccuucggc uuuccccgca ccgucaaaca cauugacgcc gcucugagcg      960

aagagaacac ggggaagaca uauuucuuug uugccaauaa auacuggaga uaugaugaau     1020

acaagcgguc uauggacccu ggauauccga aaaugaucgc ucaugauuuc cccggcaucg     1080

ggcacaaggu ggacgccgug uuuaugaagg auggauucuu uuacuucuuc cauggcaccc     1140

gccaauacaa auuugacccu aagacaaaaa gaauccucac ccugcagaag gccaacuccu     1200

gguucaacug ucggaaaaau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  3064
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt5)

<400>  3064
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

aaaacauccu gaagauucuc auggacagcu acuccaaaga gucuaagauc cagaccguga      120

gacgggucac aagcguuucc cugcuugccg uguaucugac gaugaauacc ucuagccucg      180

ugcuggcuaa acccauugaa aacacaaaug auaccuccau caagaacguc gagaaacuuc      240

gcaaugcccc uaacgaagaa aauucuaaaa agguggaaga cagcaaaaac gauaagguug      300

agcacgugaa aaauauugag gaagcgaagg ucgagcaagu ggcuccggaa guuaagucca      360

aaagcacacu gagaucugcc uccaucgcca acaccaauag cgagaaguac gacuucgagu      420

aucucaacgg ccugucuuac acagaacuga ccaaucucau caaaaacauu aaguggaauc      480

agaucaacgg gcuguuuaac uauuccacgg gaagccagaa auucuuuggc gauaagaauc      540

gggugcaggc uauuaucaac gcccuucaag agucugggcg caccuacaca gcuaaugaca      600

ugaaaggaau ugaaaccuuc acagaggucc ugagagccgg cuuuuaucuc ggguacuaca      660

acgauggacu guccuaucuu aaugaccgga acuuccagga uaagugcauc cccgcgauga      720

uugccaucca gaagaauccu aacuuuaaac ugggcaccgc ugugcaggac gaagugauca      780

cgagccucgg caagcugauu gggaaugccu ccgcuaacgc cgaggucguu aauaacugug      840

ugcccgugcu gaaacaauuc cgcgagaauc ucaaccagua cgcgccugau uaugucaagg      900

gaacagccgu gaaugaacug aucaaaggca uugaguuuga cuucucuggg gcugccuacg      960

aaaaggaugu uaagaccaug cccugguaug gaaaaaucga cccuuuuauu aacgagcuua     1020

aggcucuggg ccucuacggg aacaucacaa gcgccaccga augggccucc gacgugggaa     1080

ucuauuaccu gagcaaauuc ggccuuuacu cuaccaauag aaacgauauu guccaguccc     1140

uggagaaggc uguggacaug uauaaauacg gcaagaucgc guuuguugcc auggagcgga     1200

uuacauggga uuaugacggg aucggaagca auggcaagaa aguggaucau gacaaguucc     1260

ucgaugacgc ugaaaaacac uaccugccga agacguauac cuucgauaac gggacauuua     1320

uuauccgcgc cggagacaaa gucucugagg aaaagaucaa gagacuguac ugggccagcc     1380

gggaggugaa aucccaguuc caucgcgucg ugggcaauga uaaggcucuc gaaguuggga     1440

acgccgacga cgugcugacc augaaaauuu uuaauucucc cgaggaguau aaguucaaca     1500

caaauaucaa cggagucagc accgauaaug gcggccuuua cauugaaccu agagggacgu     1560

uuuacacaua ugagcggaca ccccaacagu ccaucuucag ccuggaggag cucuuucgcc     1620

acgaguacac ccauuaucug caggcgagau accuugugga cggacugugg ggccaagggc     1680

cuuucuauga gaaaaaccgg cucaccuggu uugaugaagg aaccgcugag uucuuugccg     1740

gcucuacaag aacguccggg guucugcccc gcaagagcau ucugggcuac cucgccaaag     1800

acaaggugga ucaccgguau ucucugaaga aaacccuuaa uuccggauac gacgauagcg     1860

acuggauguu cuacaacuau ggcuuugcug ucgcccacua ccuguaugaa aaggauaugc     1920

cgacauucau caaaaugaau aaggcuauuc ucaacaccga cgugaaaucc uacgaugaaa     1980

ucaucaagaa gcugucugac gaugccaaca aaaauacaga guaucagaac cauauucagg     2040

agcuggcgga caaguaccag ggggccggaa ucccucuugu gagcgacgau uaucucaaag     2100

accacggcua caagaaggcu uccgaaguuu acucugagau uagcaaggcc gcuucccuga     2160

ccaauacgag cgucaccgcc gaaaagucuc aauauuucaa cacauuuacc cugagaggga     2220

cauacaccgg agagacgucc aaaggcgagu ucaaggauug ggacgaaaug agcaaaaagc     2280

ucgaugggac acuggagucu cuugcgaaaa auuccuggag cggcuauaag acccugacag     2340

ccuacuuuac caacuaucgc gugaccucug acaauaaggu gcaguacgau gucguguucc     2400

auggaguucu cacagacaac gcugauauca gcaauaacaa agcccccauu gcuaagguga     2460

cgggcccuuc caccggggcc gucggacgga auaucgaauu uagcggcaaa gacucuaagg     2520

augaggacgg gaaaaucgug uccuaugauu gggacuucgg agacggcgcc acaagcagag     2580

ggaagaacuc cguucacgcu uacaaaaagg cgggcaccua caaugugaca cugaagguca     2640

ccgaugacaa aggagccacg gcuacagaau cuuuuaccau ugagaucaag aacgaagaua     2700

ccacaacccc cauuacaaaa gagauggagc ccaaugacga uaucaaggaa gccaacggcc     2760

cuauugugga ggggguuacg gugaaaggag accugaacgg cagcgaugac gccgauaccu     2820

ucuauuuuga cgucaaggaa gauggggacg ugacaaucga gcuuccguac uccggaucua     2880

gcaauuucac cuggcucgug uauaaggagg gcgacgauca gaaccacauc gcuuccggga     2940

uugacaaaaa uaacucuaag gucggcacau uuaaaagcac caagggacgc cauuacguuu     3000

ucaucuauaa acacgauucc gccagcaaua uuucuuacuc ccugaacauc aagggccugg     3060

ggaaugaaaa gcucaaagag aaggaaaaca augacagcuc ugauaaagcg acggugauuc     3120

ccaacuuuaa uaccacaaug cagggauccc ugcuuggcga cgauagccgg gacuauuacu     3180

cuuucgaggu gaaggaagag ggggagguca acaucgaacu ggauaaaaag gacgaguucg     3240

gagugaccug gacacuccau ccugaaucca auaucaacga uagaauuacc uacggccaag     3300

uugacggcaa uaaggugagc aacaaaguca agcugcgccc cgggaaauau uaccugcuug     3360

uguauaagua cuccggaagc ggcaauuaug agcuccgggu uaacaaauga ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  3065
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt5)

<400>  3065
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuucugu ucuccucugc cuacagcauu gcuaacacaa      120

auuccgagaa auaugacuuu gaauaccuua acggccuguc uuauacggag cucaccaauc      180

ugaucaagaa cauuaaaugg aaucagauca acgggcuuuu caauuacagc acaggauccc      240

aaaaguuuuu cggcgauaaa aacagagucc aggccauuau caaugcgcug caggaaucug      300

ggcggaccua uacagcuaac gacaugaagg gaaucgagac cuuuacagaa guucuccgcg      360

ccggcuucua ccugggguau uacaaugaug gacugagcua ccucaacgac agaaauuuuc      420

aggauaagug cauucccgcc augaucgcua uucagaaaaa cccuaauuuc aagcugggca      480

ccgccgugca agacgaggug aucacguccc uuggcaaacu gauugggaac gcuagcgcca      540

acgcggaggu cgugaauaac uguguuccgg ugcucaagca guuucgggaa aaucugaacc      600

aguaugcccc cgauuacguc aaaggaaccg cugugaauga gcuuaucaag ggcauugagu      660

ucgacuuuuc uggggccgcu uaugaaaagg auguuaaaac aaugccuugg uacggaaaga      720

ucgaccccuu caucaacgag cugaaagccc ucggccugua ugggaauauu accuccgcga      780

cagaaugggc cagcgaugug ggaaucuacu aucugucuaa guucggccuc uacuccacca      840

accgcaauga cauuguccaa agccuggaga aagcugugga uauguacaag uauggcaaaa      900

ucgccuuugu ggcuauggaa agaauuacgu gggacuacga cgggaucgga ucuaacggca      960

agaaggucga ucacgacaaa uuccuugaug acgccgagaa gcauuaucug ccuaaaacau     1020

acaccuuuga uaaugggaca uucaucauuc gggccggaga caagguuucc gaagagaaaa     1080

ucaagcgccu cuauugggcu agcagagagg ugaaguccca guuucaccgg guggucggca     1140

acgauaaagc gcuggaagug gggaaugccg acgauguucu uaccaugaag auuuucaacu     1200

cucccgagga auacaaauuu aauaccaaca ucaacggagu gagcacagac aauggcggcc     1260

uguauauuga gccucgcggg acguucuaca ccuacgaaag aacaccgcag caguccaucu     1320

uuagccucga ggagcuguuc cggcaugaau auacccacua ccugcaagcu cgcuaucucg     1380

ucgauggacu guggggccag gggcccuuuu acgagaagaa cagacuuaca ugguucgacg     1440

aaggaaccgc cgaguuuuuc gccggcucua cgcggacauc cggggugcug ccucgcaaaa     1500

gcauccucgg cuaucuggcu aaggacaagg uugaucauag auacucucuu aaaaagaccc     1560

ugaauagcgg auaugacgau uccgacugga uguucuacaa cuacggcuuu gccguggcgc     1620

acuaucucua cgaaaaagau augcccaccu ucauuaagau gaauaaagcu auccugaaca     1680

cagacgucaa gucuuaugau gagauuauca agaaacugag cgacgaugcc aauaagaaca     1740

ccgaguacca gaaucacauu caagaacucg ccgacaaaua ucagggggcu ggaaucccuc     1800

ugguguccga ugacuaccuu aaggaucaug gcuauaaaaa ggccagcgag gucuacucug     1860

aaauuuccaa agcugccagc cugacaaaca cgucugugac cgcggagaag ucccaguacu     1920

uuaauacauu cacccuccgg gggacauaua ccggagagac gagcaagggc gaauuuaaag     1980

acugggacga gauguccaag aaacuggaug ggacccugga aucucuugcc aagaacagcu     2040

gguccggcua caaaacacuc accgcuuauu ucacaaauua cagaguuacc ucugacaaca     2100

aggugcagua ugaugucgug uuucacggag uucugacgga caaugccgau aucagcaaca     2160

acaaggcucc caucgccaaa gugacaggcc cguccaccgg ggcggucgga cgcaauauug     2220

aguucagcgg caaggacucu aaagaugaag acgggaagau cguguccuac gauugggacu     2280

uuggagaugg cgccacaagc cgggggaaaa acucugugca ugcuuauaag aaggccggca     2340

ccuacaaugu uacccugaaa gucacagacg auaagggagc uacggccacc gaguccuuca     2400

caauugagau caaaaacgaa gacaccacaa ccccuauuac gaaggagaug gaacccaaug     2460

acgauaucaa agaggccaac ggcccuaucg uggaaggggu gacagucaag ggagaccuca     2520

auggcagcga ugacgcugau accuuuuacu ucgacgugaa ggaggauggg gacguuacca     2580

uugagcugcc cuauucugga agcuccaacu uuacauggcu uguguacaaa gaaggcgaug     2640

accaaaauca caucgcgagc gggauugaua agaacaauuc uaaagucggc accuucaagu     2700

ccacaaaagg aagacacuau guguucaucu acaagcauga cagcgccucc aacauuucuu     2760

auagccugaa uaucaaaggc cucgggaacg agaagcugaa ggaaaaagag aauaacgacu     2820

ccucugauaa ggcuacgguu auccccaacu uuaauaccac aaugcaggga agccugcuug     2880

gcgacgauuc ccgcgacuac uauucuuucg aagugaaaga ggagggggaa gucaacauug     2940

agcucgauaa gaaagacgaa uuuggaguga ccuggacacu gcacccugag agcaauauca     3000

acgaucggau uaccuacggc cagguugacg gcaauaaggu guccaacaag gucaaacuga     3060

gaccggggaa guacuaucuc cugguguaca aauauagcgg aucuggcaau uacgagcuuc     3120

gcgugaacaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  3066
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt5)

<400>  3066
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuucugu ucuccucugc cuacagcaug aaaaagaaca      120

uucuuaaaau ccugauggac uccuauucua aggagagcaa aauucagaca gucagacggg      180

uuacguccgu gucucuccug gcuguguacc uuaccaugaa uacaagcucc cugguccucg      240

ccaagcccau cgaaaacacc aaugauacaa gcauuaagaa cguggagaaa cugcgcaaug      300

cgccuaacga agaaaauucu aagaaaguug aagacuccaa gaacgauaaa guggagcacg      360

ucaagaauau cgaggaagcu aagguggagc aaguugcccc ggaagugaaa agcaagucua      420

cccugagauc cgccagccgg cgcagacgga aacgcaucgc uaacacaaau ucugagaagu      480

augacuuuga guaccucaac ggccuguccu auaccgaacu uacgaaucug auuaaaaaca      540

ucaaguggaa ucagauuaac ggacucuuca acuacagcac cggaucccag aaauuuuucg      600

gcgauaagaa uagaguccag gccaucauua acgcucugca agagucuggg cggacauaua      660

ccgccaauga caugaaggga aucgaaacau uuaccgaggu gcuucgcgcg ggcuucuacc      720

ugggguacua uaacgaugga cucagcuacc ugaaugacag aaacuuucag gauaaaugca      780

uucccgccau gaucgcuauc cagaagaauc cuaacuucaa acugggcacg gccgugcagg      840

acgaagucau uacaucccuc ggcaagcuga ucgggaaugc uagcgccaac gcggagguug      900

ugaauaacug ugugcccguc cuuaaacaau uucgggagaa ucugaaccag uaugccccug      960

auuacgugaa gggaaccgcu guuaaugaac ucauuaaggg caucgaguuc gacuuuucug     1020

gggccgcuua ugaaaaagau gugaagacaa ugcccuggua cggaaaaauu gacccuuuca     1080

ucaacgagcu gaaggcccuu ggccuguaug ggaacaucac cuccgccacc gaaugggcua     1140

gcgacgucgg aauuuacuac cucucuaaau ucggccugua uagcacaaau cgcaacgaua     1200

ucgugcaguc ccuggagaag gcgguugaca uguacaagua uggcaaaauu gccuuugugg     1260

cuauggagag aaucacgugg gauuacgacg ggauuggauc uaauggcaag aaagucgauc     1320

augacaaguu ccucgaugac gccgaaaaac acuaucugcc gaagaccuac acauuugaua     1380

acgggaccuu caucauccgg gccggagaca aggugagcga ggaaaagauu aagcgccuuu     1440

auugggcuuc cagagagguc aaaagccagu uucaucgggu gguuggcaau gauaaggccc     1500

uggaaguggg gaacgcggac gacguccuca caaugaaaau cuucaauucu cccgaggagu     1560

acaaguuuaa caccaauauu aacggagugu ccacggauaa uggcggccug uacaucgaac     1620

cuagagggac auucuauacc uacgagcgca caccccaaca gagcauuuuu agccuugagg     1680

agcuguuccg gcacgaguau acccauuacc uccaggcuag auaucugguu gacggacugu     1740

ggggccaagg gccuuuuuac gagaaaaacc gccucaccug guucgaugaa ggaacagccg     1800

aauuuuucgc cggcuccacg cggaccagcg gggugcugcc cagaaagucc auccuuggcu     1860

aucuggcuaa ggacaaaguc gaucaccgcu acucucucaa gaaaacacug aauagcggau     1920

acgacgauuc cgacuggaug uucuauaacu acggcuuugc cguggcucac uaucuguacg     1980

agaaggauau gccgaccuuc auuaaaauga auaaggccau ccuuaacaca gacgugaagu     2040

cuuaugauga aaucauuaaa aagcucagcg acgaugcgaa caaaaauacc gaguaccaga     2100

accauaucca ggagcuggcc gacaaguauc agggggcugg gauuccucug guuuccgacg     2160

auuaccucaa agaccacggc uacaagaagg ccagcgaagu cuauucugag aucuccaaag     2220

cugccagccu gacgaauacc ucugugacag cggaaaaguc ccaauacuuu aacaccuuca     2280

cacuucgggg gaccuauacg ggagagacaa gcaaaggcga auuuaaggau ugggacgaga     2340

ugucuaaaaa gcuggauggg acccucgaga gccuggccaa aaauuccugg agcggcuaca     2400

aaacacugac cgcuuauuuc accaacuaca gagugacauc ugacaauaag guccaguaug     2460

augugguuuu ucauggagug cuuacggaca acgccgauau uuccaauaac aaagcuccca     2520

ucgccaaggu caccggcccu agcacagggg ccgugggacg caauaucgag uucuccggca     2580

aagacucuaa ggaugaagac gggaaaauug uuagcuacga uugggacuuu ggagacggcg     2640

cuaccucccg ggggaagaac ucugugcacg cguacaagaa agccggcaca uauaauguca     2700

cccucaaggu gacggaugac aaaggagcua cagccaccga aucuuucacc aucgagauua     2760

agaacgaaga uacaaccaca cccaucacga aagagaugga gcccaaugac gauauuaagg     2820

aagccaacgg cccuaucguu gaggggguga ccgucaaggg agaccugaac ggcuccgaug     2880

acgcugauac auuuuacuuc gacgugaaag aagaugggga cgugaccauc gagcugccgu     2940

auucuggaag cuccaauuuu acauggcucg ucuacaagga gggcgacgau cagaaccaca     3000

uugccagcgg gaucgacaaa aauaacucua agguuggcac cuucaaaucc acgaagggaa     3060

gacauuaugu guucauuuac aagcacgaua gcgcgucuaa uaucuccuau agccugaaca     3120

uuaaaggccu ugggaaugaa aagcugaaag agaaggaaaa caaugacucu uccgauaaag     3180

cuaccgugau ccccaacuuu aauacaacca ugcagggaag ccuccugggc gacgauuccc     3240

gcgacuacua cagcuucgag gucaaggaag agggggaggu gaacaucgaa cuggauaaga     3300

aagacgaguu uggaguuaca uggacccuuc auccugaauc uaauauuaac gaucggauca     3360

cauauggcca aguggacggc aauaagguca gcaacaaagu gaagcucaga cccgggaaau     3420

acuaucugcu gguuuacaag uauuccggau cuggcaauua cgagcuccgg gugaacaagu     3480

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  3067
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt5)

<400>  3067
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugaagau cauucucaau agaggcaaaa ccaugaagcg gaaaugccug agcaagcgcc      120

uuaugcuggc caucacaaug gcuacgauuu uuaccgugaa cuccacacuc cccaucuacg      180

ccgcggucga caaaaauaac gcuaccgccg ccguucagaa ugagucuaag agauauacag      240

ugagcuaccu gaagacccuu aacuauuacg aucuggugga ccuccugguc aaaacagaaa      300

uugagaaucu gccugaucuc uuccaauauu ccucugacgc uaaggaauuu uacgggaaca      360

aaacccggau gagcuucauc auggaugaga ucggacgcag agccccgcag uauacggaaa      420

uugaccacaa gggcaucccc acccuggugg agguugugcg ggcuggguuu uaccuuggau      480

uccauaauaa agagcugaac gaaauuaaua agcgcuccuu uaaggagaga gucaucccuu      540

cuauucucgc cauccagaaa aaccccaauu ucaagcuggg cacagaagug caggauaaaa      600

uuguuagcgc gaccgggcuu cuggccggaa acgagacagc uccucccgag guggucaaua      660

acuuuacccc uauccuccaa gacuguauca agaacauuga ucgguacgcc cuggacgauc      720

ugaaauccaa ggcucucuuc aaugugcugg ccgcgccgac guaugacauc acagaauacc      780

uucgcgccac caaagagaag cccgaaaaca caccuuggua uggcaagauu gauggcuuua      840

ucaaugagcu gaaaaagcuc gcucuguacg ggaaaauuaa cgacaauaac agcuggauca      900

ucgacaaugg aauuuaucac aucgcucccc uuggcaagcu gcauucuaac aauaaaauug      960

ggaucgaaac ccucaccgag gugaugaagg ucuacccuua ucuguccaug cagcaccuuc     1020

agagcgccga ucagauuaag agacauuacg acucuaaaga ugccgaggga aacaagaucc     1080

cccucgacaa auucaagaaa gaaggcaagg agaaguacug cccgaaaaca uauacguuug     1140

augacgggaa gguuaucauu aaagccggag cucgggugga agaggaaaag gugaaacgcc     1200

uguacugggc guccaaggag gucaauagcc aauucuucag aguguauggc aucgauaagc     1260

cucuugagga aggcaacccc gacgauauuc ugaccauggu uaucuacaau ucuccugagg     1320

aauauaaacu caacuccgug cuguacgggu augacacaaa uaacggaggc auguacauug     1380

agcccgaagg gaccuuuuuc acauacgagc gggaggccca ggaaagcacc uauacgcuug     1440

aggaacuguu ucgccacgag uacacacacu aucuccaggg aagauacgcu guccccggcc     1500

agugggggcg gaccaagcug uaugauaacg acagacugac cugguacgag gaaggaggcg     1560

ccgaacucuu cgccggcucc acacgcaccu cugggauccu gccucggaaa agcauugugu     1620

ccaauaucca uaacacaacg agaaauaacc gcuauaagcu gagcgacacc guucacucua     1680

aauacggagc uuccuuugag uucuacaauu augccuguau guuuauggau uacauguaua     1740

acaaggacau gggcauccug aauaaacuca acgaucuggc gaagaauaac gacguggaug     1800

gguacgacaa uuauauucgg gaucugagcu cuaacuacgc ucuuaaugac aaguaucaag     1860

aucauaugca ggagagaauc gacaacuacg aaaaucucac agucccguuc guggccgaug     1920

acuaccuggu ccgccacgcc uauaaaaacc ccaacgagau uuacagcgag aucuccgaag     1980

uggcuaagcu gaaagaugcc aagucugagg uuaaaaagag ccaguauuuu uccaccuuca     2040

cacuccgggg aagcuacacc ggcggggcuu cuaagggcaa acuggaagac caaaaggcca     2100

ugaauaaauu uauugacgau ucccuuaaga aacuggacac guauagcugg ucuggauaca     2160

agacccucac agcguauuuc accaacuaca agguggauuc cagcaauaga gucacauacg     2220

acgugguuuu ucacggcuau cugccuaacg agggggauuc caaaaauucu cugcccuacg     2280

gaaagaucaa cggcaccuau aaagggacgg aaaaggagaa aaucaaguuc agcuccgagg     2340

gaucuuucga cccugauggc aagauuguga gcuacgaaug ggacuuuggg gauggcaaua     2400

aauccaacga ggaaaauccc gagcauagcu augacaaggu cggaacauac accgugaaac     2460

uuaaggugac agaugacaaa ggcgaaucuu ccguuagcac caccacagcc gagaucaagg     2520

aucucucuga gaacaaacug ccggucauuu auaugcacgu gccuaagucc ggggcucuga     2580

aucagaaggu ggucuucuac ggaaaaggca cguacgaccc cgacgggagc aucgccggau     2640

aucaguggga uuuuggcgac gggucugauu ucagcuccga acagaacccu agccaugugu     2700

acaccaagaa aggcgaguau acaguuaccc uccgcgugau ggacucuucc ggacaaauga     2760

gcgaaaagac aaugaaaauu aagaucaccg aucccgucua cccuaucggc acggagaagg     2820

agcccaauaa cuccaaagaa acagcuucug ggccgauugu gccuggaauc cccguuagcg     2880

gcaccauuga gaauaccucc gaccaggauu auuuuuacuu cgacgugauc acacccgggg     2940

aagucaagau ugauaucaac aaacugggau auggcggggc caccugggug guuuacgacg     3000

agaacaauaa cgcggugucu uacgccacag augacggcca gaaucuuagc ggaaaguuua     3060

aagcugacaa gccuggccgg uauuacaucc accuguauau guucaacggg uccuacaugc     3120

cguauagaau uaauaucgaa ggaucugucg gccgcugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  3068
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt5)

<400>  3068
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

gaaaaugccu gagcaagcgg cucaugcugg ccaucaccau ggcuacaauu uucacgguga      120

acuccacccu ucccaucuac gccgcggucg acaaaaauaa cgcuacagcc gccguucaga      180

augagucuaa gcgcuauacc gugagcuacc ugaaaacacu caacuauuac gaucuggugg      240

accuucuggu caagaccgaa auugagaauc ucccugaucu guuucaauau uccucugacg      300

cuaaggaguu cuacggcaac aaaacaagaa ugagcuuuau cauggaugaa auugggcggc      360

gcgccccgca guauaccgaa aucgaccaca agggaauccc cacgcuggug gagguuguga      420

gagcuggcuu cuaccucggg uuucauaaua aagagcugaa cgaaauuaau aagcgguccu      480

ucaaagagcg cgucaucccu ucuauucuug ccauccagaa gaaccccaau uuuaagcugg      540

gaaccgaagu gcaggauaaa auuguuagcg cgacaggccu ccuggccggg aacgagaccg      600

cuccucccga gguggucaau aacuucacac cuauccuuca agacuguauu aagaauaucg      660

auagauacgc ccuggacgau cucaaaucca aggcucuguu uaacgugcug gccgcgccga      720

ccuaugacau cacggaauac cuccgggcca caaaagagaa gcccgaaaac accccuuggu      780

auggaaaaau ugauggcuuc aucaaugagc ugaagaaacu ugcucuguac ggcaagauua      840

acgacaauaa cagcuggauc auugacaaug ggaucuauca caucgcuccc cucggaaagc      900

ugcauucuaa caauaaaauu ggcaucgaaa cacuuaccga ggugaugaag gucuacccuu      960

aucuguccau gcagcaccuc cagagcgccg aucagauuaa acgccauuac gacucuaagg     1020

augccgaggg gaacaagauc ccccuggaca aauuuaagaa agaaggaaag gagaaauacu     1080

gcccgaagac cuauacauuc gaugacggca agguuauuau caaagccggg gcuagagugg     1140

aagaggaaaa ggugaaacgg cuguacuggg cguccaagga ggucaauagc caauuuuucc     1200

gcguguaugg aaucgauaaa ccucucgagg aaggcaaccc cgacgauauu cugacgaugg     1260

uuaucuacaa uucuccugag gaauauaaac uuaacuccgu gcuguacggc uaugacacca     1320

auaacggggg aauguacauu gagcccgaag gcacauucuu uaccuacgag agagaggccc     1380

aggaaagcac auauacccuc gaggaacugu uccggcacga guacacgcac uaucuucagg     1440

ggcgcuacgc uguccccgga caguggggca gaacaaagcu guaugauaau gaccggcuca     1500

ccugguacga ggaaggggga gccgagcugu uugccggcuc caccagaaca ucuggcaucc     1560

ugccucgcaa gagcauugug uccaacaucc auaacaccac acggaauaac agauauaagc     1620

ucagcgacac gguucacucu aaauacgggg cuuccuucga auuuuacaau uaugccugua     1680

uguucaugga uuacauguau aacaaggaca ugggcauucu gaauaaacuu aacgaucugg     1740

cgaagaauaa cgacguggau ggauacgaca auuauauccg cgaucucagc ucuaacuacg     1800

cucugaauga caaauaucaa gaucauaugc aggagcggau cgacaacuac gaaaaucuga     1860

ccgucccguu uguggccgau gacuaccuug ucagacacgc cuauaagaac cccaaugaga     1920

uuuacagcga gaucuccgaa guggcuaagc ucaaagaugc caagucugag guuaaaaaga     1980

gccaguauuu cuccacauuu acccugcgcg ggagcuacac aggaggcgcu ucuaaaggga     2040

agcuggaaga ccaaaaggcc augaacaaau ucauugacga uucccucaag aaacuggaca     2100

ccuauagcug gucuggcuac aagacgcuua ccgcguauuu uacaaacuac aaaguggauu     2160

ccagcaaucg ggucaccuac gacgugguuu uccacggaua ucugccuaac gagggcgauu     2220

ccaaaaauuc ucuccccuac gggaagauca acggaacaua uaagggcacc gaaaaggaga     2280

aaauuaaguu uagcuccgag gggucuuucg acccugaugg aaaaaucgug agcuacgaau     2340

gggacuucgg cgaugggaau aaguccaacg aggaaaaucc cgagcauagc uaugacaagg     2400

ucggcacgua cacagugaaa cugaagguga ccgaugacaa aggagaaucu uccguuagca     2460

caaccaccgc cgagaucaag gaucugucug agaacaaacu uccggucauu uauaugcacg     2520

ugccuaaguc cggcgcucuc aaucagaaag uggucuuuua cgggaaggga acauacgacc     2580

ccgacggcag caucgccggg uaucaguggg auuucggaga cggcucugau uuuagcuccg     2640

aacagaaccc uagccaugug uacacgaaga aaggggagua uaccguuaca cugagaguga     2700

uggacucuuc cggccaaaug agcgaaaaga ccaugaaaau uaagaucaca gaucccgucu     2760

acccuauugg aaccgagaaa gagcccaaua acuccaagga aacggcuucu ggcccgaucg     2820

ugccugggau ccccguuagc ggaacaauug agaauaccuc cgaccaggau uauuucuacu     2880

uugacgugau cacccccggc gaagucaaga uugauaucaa caaacugggg uauggaggcg     2940

ccacaugggu gguuuacgac gagaauaaca acgcgguguc uuacgccacc gaugacgggc     3000

agaaucucag cggcaaguuc aaagcugaca agccuggacg cuauuacauu caccuguaua     3060

uguuuaacgg cuccuacaug ccguaucgga ucaauaucga agggucuguc ggaagaugag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  3069
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt5)

<400>  3069
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuucugu ucuccucugc cuacagcguc cagaacgagu      120

ccaaaagaua uacaguuucu uaccuuaaga cgcugaauua uuacgaccuc guggaucugc      180

uugugaaaac cgaaauugag aaccugcccg accucuuuca auauagcucc gaugcuaagg      240

aguucuacgg caauaaaaca cggaugucuu uuaucaugga cgaaauuggg cgcagagccc      300

cucaguauac cgaaaucgau cacaagggca uuccgacacu ggucgaggug guucgggcgg      360

gauucuaccu gggguuucau aacaaggagc ucaaugaaau caacaaacgc agcuucaagg      420

agagagugau ccccuccauu cuggcuaucc agaaaaaucc uaacuuuaag cugggaaccg      480

aaguccagga caaaauugug agcgccacag gccugcucgc cgggaaugag accgcucccc      540

cugagguugu gaacaauuuc acgcccaucc ugcaagauug cauuaagaac aucgaccggu      600

acgcccuuga ugaccugaag ucuaaagcuc ucuuuaaugu ccuggccgcg ccuaccuaug      660

auauuacaga auaccugcgc gccaccaagg agaaaccgga aaacacaccc ugguauggaa      720

agaucgacgg cuucaucaau gagcucaaaa agcuggcucu uuacggcaaa auuaacgaua      780

acaauuccug gaucauugac aacgggaucu aucacauugc cccucuggga aagcuccaua      840

gcaauaacaa gaucggcauc gaaacccuga cggaggugau gaaaguguac cccuaucuuu      900

cuaugcagca ccuucagucc gcugaccaga uuaagagaca uuacgauagc aaagacgccg      960

aggggaauaa gaucccucuc gauaaauuua agaaggaagg aaaagagaag uacuguccca     1020

aaacauauac cuucgacgau ggcaagguca uuaucaaagc gggggcccgg guugaagagg     1080

aaaaggugaa gcgccuguac ugggcuucua aagaggugaa cucccaauuc uuuagagucu     1140

auggaauuga caagccgcug gaggaaggca auccugauga cauccucaca auggugaucu     1200

acaacagccc cgaggaauau aaacuuaauu ccguucuuua cggcuaugau accaacaaug     1260

ggggaaugua cauugagccu gaaggcaccu ucuuuacaua cgagcgggag gcccaggaau     1320

cuacguauac ccuggaggaa cucuuccgcc acgaguacac acacuaucug caggggagau     1380

acgcugugcc cggacagugg ggccggacca agcuguauga caacgaucgc cugacauggu     1440

acgaggaagg gggagccgag cucuuugccg gcagcaccag aacguccggc auccugcccc     1500

ggaaaagcau ugucucuaau auccauaaca caaccagaaa uaaccgcuau aagcuguccg     1560

acaccgugca cagcaaguac ggggcuucuu ucgaauuuua caacuaugcg ugcauguuca     1620

uggacuacau guauaauaaa gauaugggca uucucaacaa gcugaaugac cuugccaaaa     1680

acaaugaugu ugacggauac gauaacuaua uccgggaccu gagcuccaau uacgcucuca     1740

acgauaagua ucaagaccau augcaggaga gaauugauaa uuacgaaaac cugacagugc     1800

cuuuugucgc cgacgauuac cuggugcgcc acgccuauaa aaauccgaac gagaucuacu     1860

cugagaucag cgaagucgcu aaacuuaagg acgccaaguc cgaggugaag aaaagccagu     1920

auuucucuac cuuuacacuc cggggguccu acacgggagg cgcgagcaag gggaaacugg     1980

aagaucaaaa ggcuaugaau aaauucauug acgacucucu gaagaagcuc gauaccuauu     2040

ccuggagcgg cuacaaaaca cugaccgccu auuuuacaaa cuacaagguu gacuccucua     2100

auagagugac cuacgauguc guguuccacg gauaucuucc caacgagggc gacagcaaaa     2160

acucccugcc uuacgggaag aucaauggaa cguauaaagg caccgaaaag gagaagauua     2220

aauucucuag cgaggggucc uuugaucccg acggaaagau cguuagcuac gaaugggauu     2280

ucggcgacgg gaacaaaucu aaugaggaaa acccugagca uuccuaugau aaggugggca     2340

cauacaccgu caaacucaag gugacagacg auaagggaga aagcucugug uccaccacga     2400

cagccgagau uaaagaccug agcgagaaua agcugcccgu uaucuauaug cacgucccga     2460

aaucuggcgc ucuuaaccag aagguggugu uuuacgggaa aggaaccuac gauccugacg     2520

gcagcaucgc cggguaucag ugggacuucg gagauggcuc cgacuuuagc ucugaacaga     2580

aucccuccca ugucuacaca aagaaagggg aguauaccgu gacccuccgc guuauggaua     2640

gcuccggcca aaugucugaa aagacaauga agauuaaaau cacggacccu guguacccca     2700

uuggaaccga gaaggagccu aacaauagca aagaaacagc uuccggcccc aucgucccgg     2760

ggauuccugu gucuggaacc aucgagaaca caagcgauca ggacuauuuc uacuuugaug     2820

uuaucacccc cggcgaagug aagauugaca ucaauaaacu gggguaugga ggcgccacgu     2880

gggucgugua cgaugagaac aauaacgcgg uuuccuacgc cacagacgau gggcagaauc     2940

ugucuggcaa guucaaggcu gacaaacccg gacgguauua cauucaccuc uauauguuua     3000

acggcagcua caugccuuau agaaucaaca uugaaggguc cgugggacgc ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3070
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt5)

<400>  3070
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuucugu ucuccucugc cuacagcaug aaaagaaagu      120

gccuuuccaa acggcugaug cucgcuauua caauggccac gaucuuuacc gucaacucua      180

cacugcccau uuaugcggcu guugacaaga auaacgccac cgccgcucgc agacggcgca      240

aaagagugca gaaugagagc aagcgguaca caguguccua ucuuaagacc cugaacuacu      300

augaucucgu cgaccugcug gugaaaacag aaaucgagaa ucucccugau cuguuccaau      360

acucuagcga cgccaaggaa uuuuauggca acaaaacccg cauguccuuc auuauggaug      420

agaucgggag acgggcuccg caguacacgg aaaucgacca caagggcauu cccacccuug      480

uugagguggu ccgcgccgga uuuuaccugg gguuccauaa uaaagagcuc aacgaaauca      540

auaagagauc cuuuaaggag cgggugauuc cuucuauccu ggcgauucag aaaaacccca      600

auuucaaacu uggaacagaa guucaggaua agaucguguc cgccaccggc cugcucgcug      660

ggaacgagac agccccuccc gaggucguga auaacuuuac cccuauucug caagacugua      720

ucaagaauau cgaucgcuau gcucuggacg aucucaaaag caaggcccug uucaacgugc      780

uugcggcccc gacguacgac auuacagaau aucugagagc uaccaaagag aagcccgaaa      840

acacaccuug guacggaaag aucgauggcu uuauuaauga gcucaaaaag cuggcccuuu      900

auggcaaaau caacgacaau aacucuugga uuaucgacaa ugggaucuac cacauugcuc      960

cccugggaaa gcuccauucc aacaauaaaa ucggcauuga aacccugacc gaggucauga     1020

agguuuaucc uuaccugagc augcagcacc uccagucugc cgaucagauc aagcggcauu     1080

acgacuccaa agaugccgag gggaacaaga uuccccugga caaauucaag aaagaaggaa     1140

aggagaagua uugcccgaaa acauacacgu ucgaugacgg caaggugauc aucaaagcug     1200

gggcgcgcgu ggaagaggaa aaggucaaaa gacuuuauug ggccagcaag gaggugaaua     1260

gccaauuuuu ccggguuuac ggaauugaua agccucugga ggaaggcaac cccgacgaua     1320

uccucaccau ggugauuuau aauucuccug aggaauacaa acugaacagc guccuuuaug     1380

gcuacgacac aaauaacggg ggaauguaca ucgagcccga aggcaccuuu uucacauaug     1440

agagagaggc ucaggaaucc accuacacgc uggaggaacu cuuucgccac gaguauacac     1500

acuaccugca ggggcgguau gccgugcccg gacagugggg cagaaccaag cuguacgaua     1560

augaccgccu caccugguau gaggaagggg gagccgagcu guucgcuggc agcacacgga     1620

ccucuggcau ucuuccuaga aaauccaucg uuagcaacau ucauaacaca acgcgcaaua     1680

accgguacaa gcugucugac accgugcaca gcaaauacgg ggccuccuuu gaguucuaua     1740

auuacgcgug uauguuuaug gauuauaugu acaacaagga caugggaauc cucaauaaac     1800

ugaacgaucu ggcuaagaau aacgacgucg auggcuauga caauuacauc agagaucuuu     1860

cuagcaacua ugcccucaau gacaaguacc aagaucauau gcaggaacgc auugacaacu     1920

acgaaaaucu gacagugccg uucgucgccg augacuaucu ggugcggcac gcuuacaaaa     1980

accccaauga gaucuauucc gagauuagcg aaguugccaa gcucaaagau gcuaagucug     2040

aggugaaaaa gucccaguac uuuagcaccu ucacacugag agggucuuau accggaggcg     2100

ccuccaaggg gaaacuugaa gaccaaaagg cgaugaacaa auuuaucgac gauagccuga     2160

agaaacucga cacguacucc uggucuggcu auaagacccu gacagccuac uucaccaacu     2220

acaaggucga uagcuccaau cgcgugacau augacguugu guuccacgga uaccugccua     2280

acgagggcga uucuaaaaau agccuucccu augggaagau uaacggaacc uacaaaggca     2340

cggaaaagga gaaaaucaag uuuuccagcg aggggucuuu cgacccugau ggaaagaucg     2400

ucuccuauga augggacuuu ggcgauggga auaaaagcaa cgaggaaaau cccgagcauu     2460

cuuacgacaa ggugggcaca uauaccguga aacucaaggu uacagaugac aaaggagaau     2520

ccagcgucuc uaccaccaca gcugagauua aggaucugag cgagaacaaa cugccgguga     2580

ucuacaugca cgugccuaag uccggcgccc ucaaucagaa ggucguguuc uacgggaaag     2640

gaacguauga ccccgacggc agcauugcug gguaccagug ggauuuugga gacggcucug     2700

auuucuccag cgaacagaac ccuucccaug uuuauaccaa gaaaggggag uacacaguga     2760

cccugcgggu cauggacucu agcggccaaa uguccgaaaa gacaaugaaa aucaagauua     2820

ccgaucccgu guauccuauc ggaacggaga aggagcccaa uaacucuaaa gaaacagcca     2880

gcggcccgau cguuccuggg auucccgugu ccggaaccau cgagaauacc ucugaccagg     2940

auuacuuuua uuucgacguc auuacacccg gcgaagugaa gaucgauauu aacaaacuug     3000

gguacggagg cgcgaccugg guuguguacg acgagaauaa caacgccguc agcuaugcua     3060

cagaugacgg gcagaaucug uccggcaagu uuaaagccga caagccugga agauacuaua     3120

uccaccucua cauguucaac ggcagcuaua ugccguaccg gaucaauauu gaagggucug     3180

ugggacgcug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  3071
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt5)

<400>  3071
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg cugccuuugc gaugccccuu ccuccgcacc      120

ccggacaucc uggcuacauu aacuucagcu augaggugcu gacaccccuc aagugguacc      180

aguccaucag accucccuau ccuucuuacg gguaugaacc gaugggaggc uggcugcacc      240

aucaaauuau ccccguccuu agccagcagc acccucccac gcauacccug cagccucacc      300

accauauucc cguugugccg gcucaacagc cugugauccc ccagcagccu augaugcccg      360

uccccgggca acacuccaug acaccuaucc agcaucacca gccgaaucug cccccucccg      420

cccagcaacc uuaccagccc cagccggugc aaccucagcc ccaccagccu augcagcccc      480

aaccucccgu ucauccgaug cagccucucc cuccccagcc cccgcugccc ccuauguuuc      540

ccaugcagcc ucugcccccu augcuccccg accuuacccu ggaggccugg ccgucuacag      600

auaaaaccaa gcgggaagag guggacugag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  3072
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt5)

<400>  3072
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccgca ccccggccau ccuggguaca ucaacuucag cuaugaggug cucaccccuc      120

ugaaguggua ccaguccauu agaccucccu aucccucuua cggauaugaa ccgaugggcg      180

gguggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  3073
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt5)

<400>  3073
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccgca ccccggccau ccuggguaca ucaacuucag cuaugaggug cucacacccc      120

ugaaguggua ccaguccauu agaccucccc cuaugcuucc ggaccugacc cucgaagccu      180

ggcccucuac ggauaaaacc aagcgggagg aagucgacug aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  3074
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt5)

<400>  3074
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcucc cagaacccug guccuccugc uuagcggcgc ccuggcgcuc acacagacgu      120

gggcuaugcc ucugccgccc cacccugggc aucccggaua caucaacuuc uccuaugagg      180

uucuuacccc ucugaagugg uaccaaucua uucggccccc uuauccgagc uacggcuaug      240

aacccauggg agggugguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  3075
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt5)

<400>  3075
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcucc cagaacccug guccuccugc uuagcggcgc ccuggcgcuc acacagacgu      120

gggcuaugcc ucugccgccc cacccugggc aucccggaua caucaacuuc uccuaugagg      180

uucuuacccc ucugaagugg uaccaaucua uucggccccc uccgaugcuc cccgaccuga      240

cacuggaagc cuggccuagc accgauaaaa caaagcgcga ggaaguggac ugaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  3076
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt5)

<400>  3076
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cucguggggg cugccuuugc gaugccccug ccuccgcacc      120

ccggacaucc uggcuacauu aacuucagcu augagguccu uacaccccug aagugguacc      180

aguccaugau cagaccuccc uauucuagcu acggguauga accuauggga ggcuggcucc      240

accaucaaau uaucccgguu gugucccagc agcacccccu gacgcauacc cuucagucuc      300

accaccauau uccugugguc cccgcucaac agccucgggu gcgccagcag gcccugaugc      360

ccguuccggg gcaacagagc augacaccua cccagcacca ucagcccaau cucccucugc      420

ccgcccaaca gcccuuucag ccucaaccgg ugcagcccca gccucaccag cccaugcaac      480

cucagccccc gguccagccu augcagcccc ugcucccuca acccccucug cccccgaugu      540

ucccucuuag accccugccc ccuauccucc cggaccugca ccuugaggcu uggcccgcca      600

cagauaaaac caagcaggaa gagguggacu gaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  3077
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt5)

<400>  3077
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccgca ccccggccau ccuggguaca ucaacuucag cuaugaggug cucaccccuc      120

ugaaguggua ccaguccaug auuagaccuc ccuauucuag cuacggauau gaacccaugg      180

gcggguggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3078
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt5)

<400>  3078
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccgca ccccggccau ccuggguaca ucaacuucag cuaugaggug cucacacccc      120

ugaaguggua ccaguccaug auuagaccuc ccccuauccu uccggaccug caccucgaag      180

ccuggcccgc uaccgauaaa acgaagcaag aggaagucga cugaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3079
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt5)

<400>  3079
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcucc cagaacccug guccuccugc uuagcggcgc ccuggcgcuc acacagacgu      120

gggcuaugcc ucugccgccc cacccugggc aucccggaua caucaacuuc uccuaugagg      180

uucuuacccc ucugaagugg uaccaaucua ugauucggcc cccuuauagc uccuacggcu      240

augaaccgau gggagggugg ugaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3080
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt5)

<400>  3080
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcucc cagaacccug guccuccugc uuagcggcgc ccuggcgcuc acacagacgu      120

gggcuaugcc ucugccgccc cacccugggc aucccggaua caucaacuuc uccuaugagg      180

uucuuacccc ucugaagugg uaccaaucua ugauucggcc cccuccgauc cuccccgacc      240

ugcaccugga agccuggccu gccacagaua aaaccaagca ggaggaagug gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3081
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt5)

<400>  3081
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg cugccuuuag caugccccuu ccuccgcacc      120

ccggacaucc uggcuacauu aacuucuccu augaggugcu gacaccccuc aagugguacc      180

agaauaugau cagacacccu uauacgucuu acggguauga acccauggga ggcuggcugc      240

aucaccaaau uaucccuguc guuagccagc agaccccgca gucccaugcg cuucaacccc      300

accaccauau uccuauggug cccgcucagc agccugggau cccccagcaa ccgaugaugc      360

cucugcccgg acagcacucu augacaccua cccagcauca ccagcccaac cucccccugc      420

cugcccaaca gccguuucag ccccaaccug ugcagcccca gccucaccag ccccugcaac      480

cgcagagccc uaugcauccc auccagccuc uccugcccca gccuccccuu ccgccuaugu      540

ucuccaugca aucucugcuc cccgaccugc cccuugaggc cuggccugcu acagauaaaa      600

ccaagcggga agaggucgac ugaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3082
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt5)

<400>  3082
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccgca ccccggccau ccuggguaca ucaacuucag cuaugaggug cucacacccc      120

ugaaguggua ccagaauaug auuagacacc cuuauaccuc cuacggauau gaacccaugg      180

gcggguggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3083
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt5)

<400>  3083
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccgca ccccggccau ccuggguaca ucaacuucag cuaugaggug cucacacccc      120

ugaaguggua ccagaauaug auuagacacc cuucccuucu gcccgaccuc ccucuggaag      180

ccuggccggc uaccgauaaa acgaagcggg aggaagucga cugaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3084
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt5)

<400>  3084
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcucc cagaacccug guccuccugc uuagcggcgc ccuggcgcuc acacagacgu      120

gggcuaugcc ucugccgccc cacccugggc aucccggaua caucaacuuc uccuaugagg      180

uucuuacccc ucugaagugg uaccaaaaua ugauucggca ccccuauaca ucuuacggcu      240

augaaccuau gggagggugg ugaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3085
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt5)

<400>  3085
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcucc cagaacccug guccuccugc uuagcggcgc ccuggcgcuc acacagacgu      120

gggcuaugcc ucugccgccc cacccugggc aucccggaua caucaacuuc uccuaugagg      180

uucuuacccc ucugaagugg uaccaaaaua ugauucggca ccccucucuc cugccugacc      240

ugccgcucga agccuggccc gccacagaua aaaccaagcg cgaggaagug gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3086
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt5)

<400>  3086
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg cugccuuuag caugccccuu ccuccgcacc      120

ccggacaucc uggcuacauu aacuucuccu auaucagaca ccccuacaca ucuuaugggu      180

acgagccuau gggaggcugg cugcaucacc agauuauccc cguggucagc caacagacgc      240

cucaguccca ugcgcuccag ccgcaccacc auauucccau gguuccugcu caacagcccg      300

ggaucccuca gcagcccaug augccgcugc cuggacaaca cucuaugacc cccacacagc      360

aucaccagcc uaaucuuccc cugcccgccc agcaaccuuu ucagccgcag cccgugcaac      420

cucagcccca ccagccucuc cagccccaaa gcccgaugca uccuauccag ccccugcugc      480

cucagccccc ucugcccccg auguucucca ugcagucucu ccuuccugac cugccccucg      540

aagccuggcc cgcuaccgau aagacaaaac gggaggaagu ggacugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  3087
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt5)

<400>  3087
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggaucuu cuuugccugc cugcucgggg cuagccuggc caugccccuu ccuccgcacc      120

ccggacaucc uggcuacauu aacuucuccu augaggugcu gacaccccuc aagugguacc      180

agaauaugau cagacacccu uauacgucuu acggguauga acccauggga ggcuggcugc      240

aucaccaaau uaucccuguc guuagccagc agaccccgca gucccaugcg cuucaacccc      300

accaccauau uccuauggug cccgcucagc agccugggau cccccagcaa ccgaugaugc      360

cucugcccgg acagcacucu augacaccua cccagcauca ccagcccaac cucccccugc      420

cugcccaaca gccguuucag ccccaaccug ugcagcccca gccucaccag ccccugcaac      480

cgcagagccc uaugcauccc auccagccuc uccugcccca gccuccccuu ccgccuaugu      540

ucuccaugca aucucugcuc cccgaccugc cccuugaggc cuggccugcu acagauaaaa      600

ccaagcggga agaggucgac ugaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3088
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt5)

<400>  3088
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg cugccuuuag caugccccuu ccuccgcacc      120

ccggacaucc uggcuacauu aacuucuccu augaggugcu gacaccccuc aagugguacc      180

agaauaugau cagacacccu ucucugcuuc ccgaccugcc ucucgaagcg uggccggcua      240

cggauaaaac caagcgggag gaagucgacu gaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  3089
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt5)

<400>  3089
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg cugccuuuag caugccccuu ccuccgcacc      120

ccggacaucc uggcuacauu aacuucuccu augaggaccu guaccucgaa gcgaucagaa      180

uugaucggac agcuuuugug cugacgcccc uuaaguggua ucagaauaug auccgccacc      240

cuuacaccuc uuauggguac gagcccaugg gaggcuggcu gcaucaccaa auuaucccug      300

ucguuagcca gcagacaccg cagucccaug cccuccaacc ccaccaccau aucccuaugg      360

ugcccgccca gcagccuggg auuccccagc aaccgaugau gccucugccc ggacagcacu      420

cuaugacccc uacacagcau caccagccca accugccccu cccugcucaa cagccguucc      480

agccccaacc ugugcagccc cagccucacc agccccugca accgcagagc ccuaugcauc      540

ccauccagcc ucuucugccc cagccucccc ucccgccuau guuuuccaug caaucucugc      600

uucccgaccu gccccucgaa gccuggccug cuaccgauaa aacaaagaga gaggaagucg      660

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  3090
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt5)

<400>  3090
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg cugccuuuag caugccccuu ccuccgcacc      120

ccggacaucc uggcuacauu aacuucuccu augaggugcu gacaccccuc aagugguacc      180

agaauaugau cagacacccu acgccccaau cucaugcgcu gcagccucac caucacauuc      240

cgaugguccc cgcucagcag ccugggaucc cccaacagcc uaugaugccc cuuccgggac      300

agcacagcau gaccccuaca cagcaucacc aacccaaccu gccucucccc gcccagcagc      360

ccuuucagcc ucaaccgguu cagccccagc cucaucaacc ccugcagccu caguccccca      420

ugcacccgau ucagccucug cucccccaac cuccccugcc ucccauguuc ucuaugcaga      480

gccuucugcc ggaccucccu cuggaagccu ggcccgcuac cgauaaaaca aagcgggagg      540

aaguggacug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  3091
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt5)

<400>  3091
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccuccgca ccccggccau ccuggguaca ucaacuucag cuaugaggug cucacacccc      120

ugaaguggua ccagaauaug auuagacacc cuuauaccuc cuacggauau gaacccaugg      180

gcggguggcu ucaucaccaa aucauuccug ucguuucuca gcagacgccg cagagccaug      240

cccugcaacc ccaccaccau aucccuaugg ugcccgcuca gcagccuggc auuccccagc      300

aaccgaugau gccucucccc ggacagcacu ccaugacccc uacacagcau caccagccca      360

accugccccu uccugcccaa cagccguuuc agccccaacc ugugcagccc cagccucacc      420

agccccugca accgcagucu ccuaugcauc ccauccagcc ucuccugccc cagccucccc      480

ugccgccuau guucagcaug caaucccucc ugcccgaccu uccccuggag gcguggccug      540

cuaccgauaa aacaaagcgg gaagaggucg acugaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  3092
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt5)

<400>  3092
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gcguggccag acugccucuc cugcuugggc ugcuccugcu uccgcggccc ggacgcccuc      120

uggaccucgc ugauuacacc uaugaccugg ccgaggaaga ugacagcgag ccccugaacu      180

acaaggaucc uugcaaagcg gcugccuucc ucggcgacau cgcccuggau gaagaggacc      240

uuagagcuuu ucagguccaa caggccguug aucugcggcg ccacacagcu agaaaguccu      300

cuauuaaagc cgcggugccc gggaauacga gcaccccuuc cugucagucu acaaacggac      360

agccgcaacg gggcgccugc gggcgcugga gaggacggag ccgcuccaga cgggcugcca      420

ccucucgccc cgaaagagug uggccugacg gcgucauccc cuucgugauu ggcgggaauu      480

uuacaggaag ccagcgggcu guuuuccgcc aggccaugag acauugggag aagcacaccu      540

gugugacauu ucucgagcgg accgaugaag acuccuauau cgucuucacg uacagaccuu      600

gcggcuguug cagcuaugug gggcgccggg gaggcgggcc ccaggcgauu ucuaucggaa      660

agaacuguga uaaguuuggc aucguugugc augagcuggg ccacgucgug ggguucuggc      720

augaacacac cagaccggac cgcgaccggc acguguccau ugucagagag aauauccaac      780

cuggacagga guacaacuuu cuuaagaugg aaccccagga gguugaaagc cugggcgaga      840

cauaugauuu cgacucuauu augcauuacg cccgcaauac cuuuucccgg gggaucuucc      900

ucgauacaau ugugccuaaa uacgaaguga acggagucaa gccucccauc ggccagagaa      960

cccgccugag caaaggggac auugcucaag cccggaagcu guauaaaugc cccgcuugug     1020

gagagacgcu ccaggauucu acaggcaauu uuuccagccc ggaguacccc aacggcuauu     1080

ccgcccacau gcauugcgug uggagaaucu cuguuacccc uggggaaaag aucauucuga     1140

auuucacaag ccuugaccug uaccgcuccc ggcucuguug guaugauuac guggagguca     1200

gagacggauu cuggcggaag gcuccccugc gcggcagauu uugcgggagc aaacuuccug     1260

aacccaucgu gucuaccgau ucccggcugu ggguugaguu cagaagcucu agcaacuggg     1320

ugggaaaggg cuuuuucgcc gucuaugaag cgauuugcgg gggcgacgug aaaaaggauu     1380

acggacacau ccaguccccg aauuacccug acgacuaucg ccccucuaaa gucuguauuu     1440

ggcggaucca agugagcgag ggcuuucacg uugggcucac cuuccagucc uuugagaucg     1500

aaagacauga uagcugcgcc uacgacuauc uggaggugcg cgauggacac ucugaaucca     1560

gcacacugau uggcagauac uguggguaug agaagccuga cgauaucaaa ucuacgucca     1620

gccggcucug gcugaaguuc gucuccgacg gaucuauuaa caaggcuggc uuugccguga     1680

auuucuuuaa agaaguugau gagugcagcc gccccaacag agggggcugu gagcagcggu     1740

gccuuaacac ccugggaucc uacaaguguu cuugcgaccc uggcuaugaa cucgcccccg     1800

auaaacgcag augugaggcu gccugcgggg gauuccugac aaaacuuaau ggcagcauca     1860

ccuccccggg guggccuaaa gaauacccuc ccaacaagaa uuguauuugg cagcuggugg     1920

cgcccacaca auaccggauc agccuccagu uugacuucuu cgagaccgag ggaaacgaug     1980

ucugcaagua ugacuuugug gaagugcgcu cuggccugac ggcugauucc aaacugcaug     2040

ggaaguucug cggcagcgag aaaccggaag uuaucacauc ucaguacaau aacaugagag     2100

ucgaguuuaa guccgacaau accgugagca aaaagggauu caaggcccac uuuuucucug     2160

acaaagauga auguagcaag gacaacggcg ggugccagca agauugugug aauaccuuug     2220

gauccuauga gugccagugu cggagcggcu ucguccucca ugacaacaaa cacgauugca     2280

aggaggccgg gugugaccac aaagugacau cuaccuccgg aacaauuacg agccccaauu     2340

ggccugauaa guaccccucc aagaaagaau gcaccugggc uaucucuagc acaccuggcc     2400

aucgcguuaa gcugaccuuu auggagaugg acauugaauc ccagcccgag ugugccuaug     2460

aucaccuuga aguguucgac gggagagaug cuaaagcccc uguccugggc cgguuuugcg     2520

gaucuaagaa acccgagccg gugcucgcga caggcagcag aauguuccug cgcuuuuacu     2580

ccgacaacuc uguucagcgg aagggguucc aagccagcca ugcuaccgag uguggaggcc     2640

aggugagagc cgaugucaaa acgaaggacc uguauuccca cgcucaguuc ggggacaaua     2700

acuacccugg aggcguggau ugcgaauggg uuaucguggc cgaggaaggc uacggggucg     2760

agcuuguguu ucagaccuuc gaaguggagg aggaaacaga cugcggauau gauuacaugg     2820

agcucuuuga cggcuaugau agcaccgcgc cccgccuggg gcgguacugu ggaucuggcc     2880

cucccgaaga ggucuauucc gccggggaca gcguucuggu gaaguuccac ucugaugaca     2940

caauuaccaa aaagggauuu caucucagau acacguccac aaaauuccaa gauacccugc     3000

acagccgcaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  3093
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt5)

<400>  3093
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

ccggcaccag augccugcuc gcucugcuuc ugccccaggu ccuccuuggg ggagccgcgg      120

gccugguucc ugagcugggg cggcgcaagu ucgcugccgc cagcuccgga agaccgucua      180

gccaacccuc cgacgaagug cucucugagu uugaacugcg gcugcucagc auguucggcc      240

ugaaacagcg cccuacaccc uccagagaug cugugguccc ucccuacaug cuugaccugu      300

aucggcgcca cucugggcag ccuggaagcc cggcccccga ucauagacuc gagcgggcug      360

ccucccgcgc gaacacggug agaucuuuuc accaugaaga gucucuggag gaacuuccug      420

agaccuccgg caagacaacc cggcgcuucu uuuucaaucu gagcucuauc cccacagaag      480

aguuuauuac cuccgccgag cuccagguuu ucagagaaca aaugcaggac gcucugggca      540

acaauagcuc uuuucaccau cggaucaaca uuuacgagau cauuaaaccu gccacagcua      600

auuccaaguu ccccgugacc cgccugcucg auacgagacu ggucaaccag aaugccagcc      660

ggugggaauc cuuugacgug accccggcgg uuaugagaug gacagcccag gggcacgcua      720

accacggauu cguggucgag guggcccauc uugaagagaa acaaggcgug ucuaagcgcc      780

acguccggau cagcagaucc cugcaucagg augagcacag cuggucucag auccgcccuc      840

uccugguuac cuuugggcac gacggaaagg gccauccccu ucacaaacgg gaaaagagac      900

aggcuaaaca uaagcaacgc aaacggcuga aguccagcug uaagagacac ccucucuaug      960

uggauuucuc ugacgugggg uggaaugauu ggauugucgc cccucccgga uaccaugccu     1020

ucuauugcca cggcgagugu cccuuuccgc uggcugacca ccugaacagc acaaaucaug     1080

cgaucgugca gacccucguu aacuccguga auagcaaaau ucccaaggcc ugcugugucc     1140

cuacggaacu gagcgcuauc uccaugcuuu accuggauga gaacgaaaaa gugguucuca     1200

agaauuauca ggacauggug gucgagggcu gcgggugucg cugaggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  3094
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt5)

<400>  3094
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaucc       60

ccggcaacag aaugcugaug gugguccucc ugugccaggu ucuucucggg ggagccagcc      120

acgcuucccu gauuccugag accggcaaga aaaagguggc cgaaauccaa gggcaugcgg      180

gaggccggcg cucugggcag agccacgagc ugcuuagaga cuucgaagcu acacugcucc      240

agauguuugg acugcggcgc agaccgcagc ccuccaaauc ugccgugauu ccugauuaca      300

ugcgggaccu guaucgccuc caaagcggcg aggaagagga ggaacagauc cauuccacgg      360

gccuggagua ccccgaaaga ccugccucuc gggcuaauac cguccgcagc uuccaccaug      420

aggagcaccu ugaaaacauu cccgggacau ccgagaauag cgccuuuaga uuccuguuua      480

accucucuuc caucccugaa aaugagguga ucagcucugc ugaacugcgg cuuuuccgcg      540

agcagguuga ucagggaccg gacugggaga gaggcuuuca ccggauuaac aucuaugaag      600

ugaugaagcc cccugccgag gucgugcccg ggcaucugau uacccgccuc cuggauacaa      660

gacugguuca ccauaaugug acccgguggg aaacauucga cgucuccccu gcggugcuca      720

gauggacccg cgagaaacaa cccaacuacg gacuggccau cgaagugacg caccuucacc      780

agacccggac acaucagggc cagcacguca gaauuagccg cucucugccg caaggguccg      840

gaaauugggc ucagcuccgg ccucugcuug uuaccuuugg ccaugauggc agagggcacg      900

cccugacacg ccggagacgc gcuaagcgga gccccaagca ucacucccag agagcccgca      960

aaaagaacaa aaauugucgg agacacucuc ucuaugugga cuucagcgau gugggaugga     1020

acgacuggau cgucgcgccu cccggcuacc aagccuuuua uugccauggg gauugucccu     1080

ucccucuggc ugaccaccuc aauuccacca accaugccau ugugcagacg cugguuaaua     1140

gcgugaacuc uuccaucccg aaggcuugcu guguccccac agagcugagc gccaucucua     1200

ugcuuuaccu ggaugaguac gacaaagugg uucucaagaa cuaucaggaa augguggucg     1260

agggaugcgg cugucgguga ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  3095
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt5)

<400>  3095
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gccuggggag acgggcccag uggcucugcu gguggugggg acugcuuugu agcugcugug      120

gcccuccgcc ccugcgcccu ccccucccug cugccgcggc ugccgccgcu gggggacaac      180

ugcuuggcga cgggggaucc cccggcagaa ccgagcagcc uccgcccucu ccucagagcu      240

ccucuggcuu ccuguaccgg cgccucaaga cacaggagaa aagagaaaug caaaaggaaa      300

uccugagcgu gcuggggcuc ccccaccggc cucgcccccu gcauggacuu cagcagccgc      360

agccucccgc ccugagacaa caggaggaac agcagcaaca gcagcaacuc ccucggggcg      420

agcccccucc cgggcgccug aaauccgcuc cgcuuuuuau gcuggaucuc uauaacgccc      480

ugucugcgga caaugaugag gacggagcca gcgaaggcga gagacagcag uccuggcccc      540

acgaagcugc cuccucuucc cagcggcgcc aaccuccccc uggggcugcc cauccccuga      600

acagaaagag ccuccuggcg ccgggaucug gcuccggcgg ggccagcccu cuuacgucug      660

cucaggauuc cgccuuccug aaugacgcug auauggucau gagcuuuguu aaccucgugg      720

aguacgacaa agaguucagc ccccggcagc gccaccauaa ggaauuuaag uucaaucugu      780

cucagauucc ugagggagaa guggucaccg ccgccgaguu uagaaucuau aaagauugcg      840

ugaugggcag cuucaagaac caaacauuuc uuauuuccau cuaccagguu cugcaggaac      900

accagcaccg ggacagcgau cucuuccugc uggacaccag aguggucugg gcuucugagg      960

agggguggcu cgaauuugau auuacagcga ccuccaaucu gugggugguu acaccccaac     1020

auaacauggg acuucagcug agcgugguca cccgcgacgg cgugcacgug cauccucggg     1080

ccgcugggcu cgucggaaga gacggccccu augauaaaca gccguucaug guugccuuuu     1140

ucaagguguc ugaggugcac guccgcacga cccggagcgc cuccucuaga cgccggcagc     1200

aaagcagaaa ucgcuccaca cagagccagg acguggcucg gguuucuucc gccagcgauu     1260

acaacucuuc cgaacugaaa accgcgugua gaaagcacga gcuuuaugug agcuuccaag     1320

accugggcug gcaggauugg aucaucgcuc cuaaggggua cgccgccaau uacugcgacg     1380

gagaauguuc cuuuccccuc aacgcucaua ugaaugccac aaaccacgcu auuguccaga     1440

cccuggugca ucugaugaau cccgaguaug uuccuaaacc gugcugugcc cccacgaagc     1500

ucaacgcgau cucugugcug uacuucgaug acaacagcaa ugucauucuu aaaaaguauc     1560

gcaacauggu gguccgggcc ugcggcuguc acugaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  3096
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt5)

<400>  3096
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

ugagaagccu gcgggccgcu gcuccccauu ccuucgucgc gcucugggcu ccucuguuuc      120

uucugcgcuc ugcccucgcc gacuucagcc uggauaacga gguucacucc ucuuuuaucc      180

auagacggcu ucgcagccag gaaagacggg agaugcaacg cgaaauucug uccauccucg      240

gccugccgca cagaccccgg ccucaucugc aggggaagca caauucugcu cccauguuca      300

ugcucgaccu guacaacgcc auggcugugg aggaaggagg cgggccugga ggccaggggu      360

uuagcuaucc cuacaaagcc guguucucca cccagggacc uccgcuugcg agccugcaag      420

auucucacuu ucucacagac gccgauaugg ucauguccuu cgugaaucug guugagcaug      480

acaaggaguu uuuccacccc cgcuaucauc acagagaauu ucgguucgau cuuagcaaaa      540

uuccugaggg cgaagcugug acggccgcug aguuucgcau cuacaaggac uauauuagag      600

agcgguucga uaacgaaacc uuccgcaucu cugucuacca ggugcugcag gagcaccucg      660

gcagagaauc cgaccuguuu cugcucgaua gccggacacu gugggccucu gaggaagggu      720

ggcuuguuuu cgacaucacc gcgacaucca aucauugggu ggucaacccc agacacaauc      780

ugggacucca gcugagcgug gagacccuug auggccaauc cauuaacccu aaacuggccg      840

ggcucaucgg acgccauggc ccccagaaua agcagccguu uaugguggcu uucuuuaagg      900

ccacagaggu ccacuuccgg ucuauuagaa gcaccggguc caaacagcgc agccaaaacc      960

ggucuaagac gccuaaaaau caggaagcuc ugagaauggc caacguugcc gaaaauucca     1020

gcucugacca gcgccaagcc ugcaagaaac augagcugua ugugagcuuu cgggaccucg     1080

gauggcagga uuggaucauu gcgcccgagg gcuacgccgc uuacuauugu gaaggcgagu     1140

gcgccuuccc ucugaacucc uacaugaaug ccaccaacca cgcuaucgug cagacacuug     1200

uccacuuuau uaaccccgag accgugccca agccuuguug cgccccgaca cagcugaaug     1260

cgaucucugu ucucuauuuc gacgauagcu ccaacgugau ccugaagaaa uacagaaaua     1320

uggucgugcg cgcuuguggg ugccauugag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  3097
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt5)

<400>  3097
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagg       60

ccagcgcugc ccugcucugc cugcuucuga ccgcggcugc cuucucuccc cagggccucg      120

cccaaccugu ggggaucaac acauccacga ccuguugcua cagauuuauu aauaaaaaga      180

ucccgaaaca gcggcuggag agcuaucgca gaacaaccuc cucucacugu ccccgggaag      240

cugucauuuu caagacaaaa cuugacaagg agaucugcgc cgauccuacc cagaaguggg      300

uucaggacuu uaugaaacau cuggauaaga aaacacaaac ccccaagcuc ugaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  3098
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt5)

<400>  3098
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugc       60

ucacccugau cauucuucug cccgugguca gcaaguucuc cuuuguuucu cucagcgccc      120

cucagcacug guccugcccg gagggcacac uggcugggaa cggaaauucu acgugugugg      180

gccccgcccc uuuccuuauc uuuagccaug ggaacuccau uuucagaauc gacaccgaag      240

gaacaaauua cgagcaacug guggucgaug cgggcguguc uguuauuaug gacuuucacu      300

auaacgaaaa acggaucuac uggguggauc ucgagcgcca gcugcugcag agagucuucc      360

ucaaugggag ccggcaggaa cgcgugugca acaucgagaa gaauguuucc ggaauggcua      420

uuaacuggau caaugaggaa gugauuugga gcaaccaaca ggagggcauc auuaccguca      480

cagacaugaa aggcaauaac ucucauaucc ugcuuuccgc ccugaaguau cccgccaaug      540

uggcugugga uccugucgaa agauuuauuu ucuggagcuc ugagguugcc gggucccucu      600

accgggcuga ccuggaugga gugggcguga aagcccuucu ggagaccagc gaaaagauca      660

cagcggucuc ucucgacgug cuggauaagc gccuguuuug gauccaguau aacagagagg      720

gguccaauag ccucauuugu uccugcgacu acgauggagg cucuguucac aucagcaaac      780

aucccaccca gcacaaccug uucgccaugu cccuuuuugg ggaccggauu uucuauagca      840

cguggaagau gaaaaccauc uggauugcua acaagcacac aggaaaagau auggugcgca      900

ucaaucugca uucuuccuuu gucccucucg gcgaacugaa ggugguucac ccgcuugccc      960

aacccaaggc ugaggacgac accugggaac cugagcagaa acuguguaag cucagaaaag     1020

gcaacugcag cucuacagug ugugggcagg aucugcagag ccaucugugc augugugccg     1080

agggauacgc gcucucccgg gaccgcaagu acugcgaaga ugucaaugag ugugccuucu     1140

ggaaccacgg cugcacccug gggugcaaaa auacgcccgg aucuuauuac uguacaugcc     1200

cugugggcuu cguccuucug cccgacggga agagauguca ccaacucgug agcugcccgc     1260

ggaacguuuc cgaauguagc caugauugcg ugcugaccuc ugagggaccu cuuuguuuuu     1320

gccccgaagg cuccguccug gagcgcgacg gcaaaacaug uagcgggugu ucuuccccug     1380

auaauggagg cugcagccag cucugcgugc cccugucccc cguuucuugg gagugcgacu     1440

guuucccugg guaugaucug cagcucgacg aaaagagcug cgcugccucc ggaccgcaac     1500

ccuuucugcu uuucgcuaac ucucaggaua ucagacacau gcauuuugac ggcaccgacu     1560

acgggacccu gcucagccag cagaugggca ugguguaugc ccuggaucac gacccugucg     1620

agaauaagau uuacuucgcc cauacagcuc ugaaauggau cgaacgggcg aacauggaug     1680

gaucccaaag agagcgccuu auugaagagg gcguggacgu gcccgagggg cucgccguug     1740

auuggaucgg acggagauuu uauuggacgg accgcggcaa gagccugauu gggcggucug     1800

aucugaaugg aaaaagaucc aagaucauca ccaaagaaaa cauuagccag ccucgcggca     1860

ucgcugucca ccccauggcc aagcggcuuu ucuggacaga caccgggauu aauccgagaa     1920

ucgagucuuc cagccugcag ggccuuggac gccuggugau ugccucuagc gaucucaucu     1980

ggccuuccgg cauuacaauc gacuuucuga ccgauaagcu guacuggugu gacgcuaaac     2040

agagcgugau cgaaauggcc aaccuugaug ggucuaagcg gagacgccuc acgcaaaaug     2100

acgucggaca ccccuucgcg guggcuguuu uugaggacua cgugugguuc uccgauuggg     2160

ccaugccuag cgucaugcgg gugaacaaaa gaacaggcaa ggaccggguu cgccugcagg     2220

gguccaugcu gaaacccucu agccucgugg ucgugcaucc ucuggccaag cccggagcug     2280

auccgugccu uuaucagaac ggcgggugug agcacauuug caagaaaaga cugggcaccg     2340

ccugguguuc cugccgggaa ggauuuauga aggcuucuga cggcaaaacc ugucucgccc     2400

uggaugggca ucagcugcuu gcgggaggcg agguugaccu caagaaucaa gugacaccuc     2460

uggauauccu gagcaaaacc agagucuccg aagacaacau uacagagucu cagcacaugc     2520

ucguggccga aaucauggug agcgaucagg acgauugcgc ucccgucggg uguuccaugu     2580

acgcccgcug cauuagcgag ggagaggacg cuacgugcca gugucugaag ggcuucgccg     2640

gggauggcaa gcucugcucu gacaucgacg aaugugagau gggaguuccc gugugcccuc     2700

cggcguccag caaauguauc aauaccgaag gcggguaugu gugccggugu ucugagggau     2760

accaaggcga ugggauucac ugccuggaca ucgaugaaug ucagcucgga gagcauuccu     2820

gcggcgagaa cgccagcugu acaaauaccg aaggcgggua uacaugcaug ugcgcuggaa     2880

gacugucuga gcccggccug auuuguccug acuccacgcc cccuccccac cuucgcgaag     2940

augaccauca cuacagcguc agaaacuccg auagcgagug cccucucucu caugacgggu     3000

auugucugca cgauggagug ugcauguaca ucgaagcccu ggacaaguac gcuuguaauu     3060

gcguuguggg cuauauuggg gagcgguguc aguaccgcga ucucaaaugg ugggagcuga     3120

gacacgccgg acauggccaa cagcagaagg ucaucguggu ugccgugugc gucgugguuc     3180

uugugaugcu gcuccugcug agccuuuggg gcgcucacua uuaccggacc cagaaacugc     3240

ucuccaagaa ccccaaaaau ccguaugaag agucuagccg cgacgucaga ucccggcgcc     3300

cugcggacac cgaagauggg augucuagcu guccccaacc uugguucgug gugaucaagg     3360

agcaucagga ccugaagaac ggaggccagc ccgucgccgg ggaggaugga caggcugccg     3420

acggcuccau gcaaccgaca ucuuggagac aggaaccuca gcucugcggg augggaaccg     3480

agcagggcug uuggauuccc guuagcuccg auaaaggcag cugcccucaa gugauggaac     3540

ggucuuuuca caugcccucc uacgggacac agacccugga gggaggcgug gaaaagcccc     3600

auagccuucu gucugccaau ccucucuggc agcaacgcgc ucuggacccg ccccaccaga     3660

uggagcugac gcagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  3099
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt5)

<400>  3099
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

ccggcagacg gauggagaug cugugcgcug ggcgcgugcc cgcccuccug cuuugucugg      120

gauuccaccu ccugcaggcg guccuuagca caacgguuau cccuuccugc auuccgggcg      180

aaucuagcga caacuguacc gcucuggugc aaacagagga uaaucccaga guggcccagg      240

ucuccaucac caagugcucu agcgacauga acggguacug ucuccaugga cagugcauuu      300

aucuggugga uaugucccag aauuacuguc ggugcgaagu uggcuauaca ggggugcgcu      360

gugagcacuu uuuccugacc guccaucaac cucucucuaa agaauacgug gcccugacag      420

uuauccuuau uauccuguuu cucaucaccg uggucggaag cacguauuac uucugcagau      480

gguaucggaa ccgcaagucc aaagagccca agaaagagua cgaaagagug accagcggcg      540

acccugagcu gccccaggug ugaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  3100
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt5)

<400>  3100
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

agggcgaaau caccacauuc acggcucuga ccgagaaguu uaaccugccc ccugggaauu      120

acaaaaagcc gaaacuccuu uauugcagca acggaggcca cuuccugcgg auucuccccg      180

acgggacagu ggauggaacc agagaccgcu ccgaucagca uauccaacug cagcuuucug      240

ccgaaagcgu cggcgagguu uacauuaagu ccacagaaac cgggcaguau cuggcgaugg      300

acacagaugg acuccuguac ggcucucaga ccccuaauga ggagugucug uuucucgaaa      360

gacuggagga aaaccacuau aauacguaca ucagcaaaaa gcaugcugag aagaacuggu      420

ucgugggccu uaaaaagaau ggguccugca aacggggacc ccgcacccac uauggccaaa      480

aggccauucu guuucucccu cugcccgugu cuagcgacug aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  3101
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt5)

<400>  3101
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

gcgucggggg aggcgacguu gaggauguga cccccagacc ugggggaugc cagaucagcg      120

gccgcggggc ccggggaugu aacggcauuc cgggcgcugc cgcgugggaa gcugcccugc      180

ccagacggcg cccuagacgg caccccuccg ugaauccucg cucuagagcc gcugggagcc      240

cccggacacg cggaagacgg acggaggaac gcccuuccgg cucuagacuc ggggaccggg      300

gacgcggcag agcccugccc gggggacggc uuggcggcag agggcgcgga cgggcucccg      360

agagagucgg cgggcgcgga cggggcagag ggaccgccgc gccucgcgcc gcucccgccg      420

cucggggaag cagaccuggc cccgccggca caauggcggc cggguccauc accacacugc      480

cggcucuccc ugaagaugga ggcucugggg ccuucccgcc uggacauuuu aaggacccca      540

aacgccugua cugcaagaac ggcggguucu uucuucggau ucaccccgau ggcagagugg      600

acggaguucg cgagaaaagc gauccucaua ucaagcugca acuccaggcu gaggaacggg      660

gcguggucuc cauuaaaggg gugugugcca auagauaucu ggccaugaag gaggacggac      720

ggcugcucgc uagcaagugc guuaccgaug aauguuucuu uuucgagcgc cuggagucua      780

acaauuacaa cacauauaga ucccggaaau acaccagcug guauguggcg cuuaagagaa      840

cgggccagua caaacugggg ucuaagaccg gaccgggcca gaaagccauc cucuuucugc      900

ccauguccgc uaagagcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  3102
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt5)

<400>  3102
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aguggauccu gaccuggauu cuccccacac ugcuuuacag aagcugcuuc cauaucauuu      120

gucugguggg cacgaucucc cucgccugca acgacaugac cccugagcag auggcuacaa      180

augucaacug uucuagcccg gaacggcaca cccgcuccua ugauuacaug gaagggggag      240

acauuagagu ucggcgccug uuuugcagaa cacaauggua ucuucggauc gauaaacgcg      300

gcaaggugaa agggacccag gagaugaaga auaacuacaa uaucauggag auuagaacag      360

uggccgucgg aaucguggcg auuaaaggcg uugaaucuga guucuaucug gcuaugaaca      420

aggaggggaa gcucuacgcc aaaaaggaau guaaugagga cugcaacuuu aaagaacuga      480

uccuggagaa ucauuauaac accuacgcca gcgcuaagug gacgcacaau ggaggcgaga      540

uguucguggc ccucaaccag aaaggcauuc ccguccgggg gaagaagacc aaaaaggaac      600

agaaaacagc ucauuuucug ccuauggcca ucaccugagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  3103
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt5)

<400>  3103
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ugcuccccag cgugguccug aaacuuuucc uggccgcugu ucucuccgcc cuggugaccg      120

gcgagucucu ugaaagacug cggcgcgggc ucgcggcugg aacaagcaac ccugacccgc      180

ccacgguguc caccgaucag cugcugccuc ucggcggggg aagagaccgg aagguccgcg      240

aucugcaaga ggccgaccuu gaucugcuca gagugacacu gucuagcaaa ccccaggccc      300

uugcuacccc uaauaaggag gaacacggca aacggaagaa gaaagggaag ggacugggca      360

aaaagcgcga ccccugccuc agaaaauaca aggauuuuug uauccauggc gaaugcaagu      420

auguuaaaga gcugcgggcc ccuuccugua uuugccaccc gggguaccau ggagagcgcu      480

gucacggccu gucucucccc guggaaaaca gacuguauac auacgaccau accacaaucc      540

uugcugucgu ggccguugug cugagcuccg ucugccuccu ggugauugug gggcuucuga      600

uguuccggua ucaccgcaga ggaggcuacg augucgagaa ugaagagaag guuaaacucg      660

ggaugaccaa cagccacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  3104
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt5)

<400>  3104
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ugaccaagcu gcuccccgcc cugcuucugc agcacguccu ccugcaucuu cugcuccugc      120

cuaucgcuau uccguacgcc gagggccaaa gaaaacggcg caacacaauc cacgaguuca      180

agaaaagcgc gaagacgacc cugauuaaaa ucgaccccgc ucucaagauu aagaccaaaa      240

agguuaauac cgccgaucag ugcgccaaca gauguacacg gaauaaaggg cugccuuuua      300

ccugcaaggc uuucguguuu gacaaagccc gcaagcagug ucuuugguuc cccuuuaacu      360

ccaugucuag cggagugaag aaagaguucg gccaugaauu ugaucuguau gagaauaagg      420

acuacaucag aaacugcauc auugggaaag gacgguccua uaagggcaca gucucuauca      480

ccaaaagcgg gauuaagugu cagccuuggu ccucuaugau cccccacgaa cauagcuucc      540

ucccuuccag cuaccgcgga aaagaucugc aagagaauua uugcagaaac ccgcggggcg      600

aggaaggcgg gcccuggugu uuuacgucua auccugaggu gcgcuacgaa guuugcgaca      660

uuccccagug uuccgaggug gagugcauga ccuguaacgg agaaagcuau agaggccuua      720

uggaucacac agagucuggg aagaucugcc agcgguggga ccaccagacc ccucaucgcc      780

acaaguuccu gcccgaaaga uacccggaua aaggauuuga cgauaauuac ugccggaacc      840

cugacggcca accccgcccu ugguguuaua cacucgaucc ccauacaaga ugggaauacu      900

gcgcuauuaa gacgugugcc gacaauacaa ugaacgacac cgaugucccc cuggaaacaa      960

ccgagugcau ccaggggcag ggagagggcu aucggggcac cgugaauaca aucuggaacg     1020

ggauuccuug ucagagaugg gacucccaau acccgcacga acacgauaug acgcccgaga     1080

acuucaaaug caaggaccug cgcgaaaauu auugucggaa cccugaugga agcgagucuc     1140

ccuggugcuu uaccacagac ccuaauauca gaguuggcua cuguucccag auucccaacu     1200

gcgauaugag ccaugggcag gacuguuauc gcggaaaugg caaaaacuac auggggaauc     1260

ucucccaaac ccggucugga cugacaugca gcauguggga uaagaacaug gaagaccuuc     1320

acagacauau cuucugggag ccggaugcgu ccaagcugaa ugagaacuac ugccgcaauc     1380

cugacgacga ugcccacggc cccugguguu auaccggcaa cccucucauu cccugggacu     1440

acugcccuau cagccggugu gaaggggaua cgacacccac caucgugaau cuggaccauc     1500

cggucauuuc uugcgcuaaa accaagcagc uuagaguggu gaacggaauc ccuacacgca     1560

ccaauauugg cuggaugguc ucccugcggu auagaaacaa acacaucugu gggggaagcc     1620

ucauuaagga gucuuggguu cugacagccc gccagugcuu ccccagccgg gaucugaaag     1680

acuacgaggc uuggcucggc auccacgaug ugcaugggag aggcgacgaa aaguguaaac     1740

aggugcugaa cgucucccaa cuuguguaug gacccgaagg cucugaucug guucucauga     1800

agcuggcccg gccugcggug cuugacgauu uugucagcac gaucgaccug ccgaauuacg     1860

ggugcaccau ucccgagaag acauccugua gcguguaugg auggggcuac accgggcuca     1920

ucaacuacga uggacugcug cgcguugccc accucuauau uaugggcaau gagaaaugcu     1980

cucagcauca cagagggaag gugacacuga acgaauccga gaucugugcu ggcgccgaga     2040

aaauuggaag cggcccuugc gaaggggacu acggaggccc ccuugucugc gagcagcaca     2100

agaugcggau ggugcugggg gucaucgugc cuggaagagg cugugcuauu cccaaucgcc     2160

cugggaucuu cguucgggug gccuauuacg ccaaguggau ccauaaaauu auccucaccu     2220

auaagguccc ccagucuuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  3105
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt5)

<400>  3105
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aggcugccgc gaucggcauu gaccugggga ccacauacag cugcguggga gucuuccagc      120

acggcaaagu ugagaucauu gcuaacgauc aagggaauag aacgaccccc uccuaugugg      180

ccuuuacaga caccgaacgg cucaucggag augccgcuaa gaaccaggug gcccugaauc      240

cucagaacac agucuucgac gcuaaacgcc uuauuggcag aaaguuuggg gauccggugg      300

uucagucuga caugaaacau uggcccuucc aagugaucaa ugauggagac aagccuaagg      360

uccaggugag cuacaaaggc gagaccaagg ccuuuuaucc cgaagagauc uccucuaugg      420

uucugacaaa aaugaaggaa auugcggagg ccuaccucgg cuauccugug accaacgcug      480

ucaucacggu gcccgccuac uucaaugaua gccagcggca ggcuaccaaa gacgccgggg      540

ugauugcggg acugaacguc cuucgcauca uuaaugagcc uacagccgcu gccaucgcuu      600

auggccugga uagaaccggg aagggagaac ggaacguucu cauuuuugac cugggcgggg      660

gaacauucga uguguccauc cugaccaucg acgacggcau uuuugaggug aaggccacgg      720

ccggcgauac acaccucggg ggagaagacu ucgauaaucg ccuggucaac cauuuugugg      780

aggaguucaa aagaaagcac aaaaaggaca ucucucaaaa uaaacgggcu guucgcagac      840

uucggaccgc gugugaacgc gccaagagaa cacugagcuc cagcacccag gcuucucucg      900

agauugauuc ccuguuugaa ggcaucgacu ucuacaccag cauuacacgg gcccgcuucg      960

aggaacuuug cucugaucug uuuagaucca cgcucgagcc gguggagaaa gcccugcggg     1020

acgcuaagcu ggauaaggcc cagauccaug accucguccu gguuggggga agcaccagaa     1080

uccccaaagu gcagaaacuu cugcaagauu ucuuuaacgg ccgcgaccuc aauaagucua     1140

uuaacccuga cgaagcggug gcuuacgggg ccgccgucca ggcugccauc cugaugggag     1200

auaaguccga gaacgugcag gaccuucugc uccuggaugu cgcuccccug agccucggcc     1260

uggaaacagc cggcggggug augaccgcgc uuauuaaacg gaauagcaca aucccuacca     1320

agcaaacgca gauuuucaca accuauucug acaaccagcc cggaguucug auccaggugu     1380

acgagggcga aagagccaug accaaggaua auaaccuccu ggggcgcuuu gagcuuagcg     1440

gaaucccgcc ugcuccccgg ggcgucccuc aaauugaggu gacauucgac aucgaugcca     1500

augggauucu gaacguuacc gcuacagaca aauccacggg caaggccaau aaaaucacca     1560

uuacaaacga uaagggaaga cucagcaaag aagagaucga acgcauggug caggaggcgg     1620

aaaaguauaa ggccgaggac gagguccagc gggaaagagu gucugcuaaa aaugcccugg     1680

aguccuacgc uuuuaacaug aaguccgccg uggaagauga gggccugaaa gggaagauuu     1740

cugaggccga caaaaagaag guucucgaua aaugucagga agucaucagc uggcuggacg     1800

cuaauacccu ugcggagaag gacgaguucg aacacaaacg caaggaacug gagcaagugu     1860

gcaaccccau cauuuccgga cucuaucagg gcgccggggg acccggcccu gggggcuuug     1920

gagcucaggg cccgaaaggg ggaucuggca gcgggcccac aaucgaggaa guggauugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3106
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt5)

<400>  3106
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aggcugccgc gaucggcauu gaccugggga ccacauacag cugcguggga gucuuccagc      120

acggcaaagu ugagaucauu gcuaacgauc aagggaauag aacgaccccc uccuaugugg      180

ccuuuacaga caccgaacgg cucaucggag augccgcuaa gaaccaggug gcccugaauc      240

cucagaacac agucuucgac gcuaaacgcc uuauuggcag aaaguuuggg gauccggugg      300

uucagucuga caugaaacau uggcccuucc aagugaucaa ugauggagac aagccuaagg      360

uccaggugag cuacaaaggc gagaccaagg ccuuuuaucc cgaagagauc uccucuaugg      420

uucugacaaa aaugaaggaa auugcggagg ccuaccucgg cuauccugug accaacgcug      480

ucaucacggu gcccgccuac uucaaugaua gccagcggca ggcuaccaaa gacgccgggg      540

ugauugcggg acugaacguc cuucgcauca uuaaugagcc uacagccgcu gccaucgcuu      600

auggccugga uagaaccggg aagggagaac ggaacguucu cauuuuugac cugggcgggg      660

gaacauucga uguguccauc cugaccaucg acgacggcau uuuugaggug aaggccacgg      720

ccggcgauac acaccucggg ggagaagacu ucgauaaucg ccuggucaac cauuuugugg      780

aggaguucaa aagaaagcac aaaaaggaca ucucucaaaa uaaacgggcu guucgcagac      840

uucggaccgc gugugaacgc gccaagagaa cacugagcuc cagcacccag gcuucucucg      900

agauugauuc ccuguuugaa ggcaucgacu ucuacaccag cauuacacgg gcccgcuucg      960

aggaacuuug cucugaucug uuuagaucca cgcucgagcc gguggagaaa gcccugcggg     1020

acgcuaagcu ggauaaggcc cagauccaug accucguccu gguuggggga agcaccagaa     1080

uccccaaagu gcagaaacuu cugcaagauu ucuuuaacgg ccgcgaccuc aauaagucua     1140

uuaacccuga cgaagcggug gcuuacgggg ccgccgucca ggcugccauc cugaugggag     1200

auaaguccga gaacgugcag gaccuucugc uccuggaugu cgcuccccug agccucggcc     1260

uggaaacagc cggcggggug augaccgcgc uuauuaaacg gaauagcaca aucccuacca     1320

agcaaacgca gauuuucaca accuauucug acaaccagcc cggaguucug auccaggugu     1380

acgagggcga aagagccaug accaaggaua auaaccuccu ggggcgcuuu gagcuuagcg     1440

gaaucccgcc ugcuccccgg ggcgucccuc aaauugaggu gacauucgac aucgaugcca     1500

augggauucu gaacguuacc gcuacagaca aauccacggg caaggccaau aaaaucacca     1560

uuacaaacga uaagggaaga cucagcaaag aagagaucga acgcauggug caggaggcgg     1620

aaaaguauaa ggccgaggac gagguccagc gggaaagagu gucugcuaaa aaugcccugg     1680

aguccuacgc uuuuaacaug aaguccgccg uggaagauga gggccugaaa gggaagauuu     1740

cugaggccga caaaaagaag guucucgaua aaugucagga agucaucagc uggcuggacg     1800

cuaauacccu ugcggagaag gacgaguucg aacacaaacg caaggaacug gagcaagugu     1860

gcaaccccau cauuuccgga cucuaucagg gcgccggggg acccggcccu gggggcuuug     1920

gagcucaggg cccgaaaggg ggaucuggca gcgggcccac aaucgaggaa guggauugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3107
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt5)

<400>  3107
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

ccgcuaaggg caucgccauu gggaucgacc ugggaacaac guacagcugc gugggcgucu      120

uccagcacgg gaagguugag auuaucgcga acgaucaagg aaauagaacc acacccuccu      180

auguggcuuu uaccgacaca gaacggcuca uuggcgaugc cgccaagaac cagguggcua      240

ugaauccuca gaacaccguc uucgacgcca aacgccugau cgggagaaag uuuaaugauc      300

cggugguuca ggcugacaug aaacuuuggc ccuuccaagu gaucaacgag ggaggcaagc      360

cuaagguccu ggugucuuac aaaggcgaaa auaaggccuu uuaucccgag gaaauuagcu      420

ccaugguucu cacaaaacug aaggagaccg cggaggccuu ccuugggcau ccugugacga      480

acgcugucau caccgugccc gccuacuuua augauucuca gcggcaggcu acaaaagacg      540

ccggagugau ugcgggccug aacguccucc gcaucauuaa ugaaccuacc gccgcugcca      600

ucgcuuaugg gcuggauaag ggaggccagg gggagagaca cguucugauu uucgaccucg      660

gaggcggcac auuugaugug agcauccuga ccaucgacga ugggauuuuc gaagugaagg      720

ccacggccgg agacacacau cuuggcgggg aggacuuuga uaaccggcug gucucccacu      780

ucguggagga auuuaaacgc aagcauaaaa aggacaucuc ucaaaauaaa agagcuguuc      840

ggcgccucag aaccgcgugu gagcgggcca agcgcacacu gagcuccagc acccaggcua      900

accuugaaau ugauucucug uacgagggaa ucgacuucua uaccuccauu acaagagccc      960

gguucgagga acucugcgcc gaucuguuuc gcggcacgcu ggagccggug gaaaaagcuc     1020

ucagagacgc caagauggau aaggcgaaaa uccacgacau cguccugguu gggggaagca     1080

cccggauucc caaggugcag agacuucugc aggauuacuu caauggccgc gaccucaaca     1140

aaucuaucaa cccugaugag gcuguggccu acggcgccgc uguccaagcc gcuauucuga     1200

ugggggacaa guccgaaaaa gugcaggacc uucugcuccu ggaugucgcg ccccugagcc     1260

ucggacugga gacagccggc ggggugauga ccgcccuuau caagcggaau agcacaauuc     1320

cuaccaagca gacgcaaauc uuuacaaccu auuccgacaa ccagcccgga guucugaucc     1380

agguguacga aggcgagaga gcuaugacca aagauaauaa ccuccugggg cgcuucgacc     1440

uuacaggcau uccgccugcu ccccggggag ucccucagau cgaggugacc uuugauauug     1500

acgccaaugg cauccugaac guuacagcca cggauaagag caccgggaaa gugaauaaga     1560

uuacaaucac caacgacaaa ggaagacucu ccaaggaaga gauugaacgc augguccugg     1620

augcggagaa guauaaagcc gaagacgagg ugcaacggga gaagaucgcu gccaaaaaug     1680

cucuggaauc uuacgccuuc aacaugaagu cugugguuuc cgaugagggc cucaaaggga     1740

agaucagcga aucugacaag aauaaaauuc uggauaagug uaacgagcuu cuguccuggc     1800

ucgaggucaa ucagcuggcc gaaaaagacg aguuugacca caagagaaaa gaacuggagc     1860

agaugugcaa ccccaucauu acaaaacuuu aucagggagg cuguaccggg cccgcuugcg     1920

gcacgggaua cgugccuggc cgcccggcga ccgggcccac aaucgaagag guggauugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3108
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt5)

<400>  3108
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

ccagaggccc cgcuaucggg auugaccugg gaaccacaua cuccugcgug ggcgucuucc      120

agcacgggaa gguugagauc auugccaacg aucaaggaaa ucggacgacc ccuucuuaug      180

uggcguuuac agacaccgaa cgccucaucg gcgaugcugc caaaaaccag guggccauga      240

auccgacaaa caccauuuuc gacgcuaaga gacugaucgg gcggaaauuu gaggaugcca      300

caguccagag cgacaugaag cauuggcccu uccgcguggu uuccgaagga ggcaaaccua      360

aggugcaggu cgaguacaag ggcgaaacca aaacguuuuu ccccgaggag aucucuagca      420

uggugcuuac caagaugaaa gaaauugcug aggccuaucu gggaggaaag guucacuccg      480

cggugaucac agucccugcc uacuuuaaug auucucaaag acaggcuacc aaagacgccg      540

gcacaauuac cgggcucaac gugcugcgga ucauuaauga acccacggcu gccgcgaucg      600

ccuauggacu ugauaagaag ggcugugcug ggggagagaa aaacgugcug auuuucgacc      660

ucggcggcgg gacauuugau gucagcaucc ugaccaucga ggacggaauu uucgaaguua      720

aguccacagc cggcgauacc caucuugggg gagaggacuu ugacaaucgc auggugagcc      780

accucgcuga agaguucaaa agaaagcaua aaaaggauau cggcccuaac aaacgggccg      840

ugcgcagacu gcggaccgcc ugcgaacgcg cuaagagaac acuuucuucc agcacgcagg      900

cgucuauuga gaucgacucc cuguacgagg gggucgauuu uuauaccagc auuacacggg      960

cccgcuucga ggaacucaau gcugaccugu ucagaggaac ccuugaaccg guggagaagg     1020

cccugcggga ugccaaacuc gacaagggcc agauccaaga aaucguucug gugggcgggu     1080

cuacacgcau ucccaaaauc cagaagcugc uccaggacuu uuucaacgga aaagagcuga     1140

auaaguccau uaacccugau gaggcugucg ccuacggcgc ggcugugcag gccgccaucc     1200

uuauugggga uaagagcgaa aauguucaag accugcuccu gcuugaugug acgccccugu     1260

cccucggaau cgagaccgcu ggcgggguca ugacaccucu gaucaaaaga aacaccacca     1320

uucccacaaa gcagacccag acauuuacga ccuacucuga caaccaaagc uccgugcugg     1380

uccaggugua ugaaggcgag cgggccauga caaaagacaa uaaccuccug ggaaaguucg     1440

aucuuaccgg caucccgccu gcucccagag ggguuccuca gauugaagug acauuugaca     1500

ucgaugccaa ugggauucug aacgucaccg cggccgacaa aagcacgggc aaggagaaua     1560

agaucaccau uacaaacgau aaagggcgcc ucucuaagga cgauaucgac cggauggugc     1620

aggaggcuga aagauacaaa uccgaggaug aagccaaucg cgaccggguu gcugccaaga     1680

acgcgcugga gagcuauacc uacaauauca aacaaacagu ggaggaugaa aagcugagag     1740

gaaagauuuc ugagcaggac aaaaacaaga uccuggauaa augucaggaa gucauuaauu     1800

ggcucgaccg caaccagaug gccgagaagg acgaauauga gcacaaacaa aaggagcugg     1860

aacgggugug caaucccauc auuagcaaac uguaccaggg cgggcccggc ggaggcuccg     1920

ggggaggcgg gucuggagcu agcggcgggc cuaccaucga ggaaguggau ugaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  3109
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt5)

<400>  3109
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggucggcau cgaccugggg uuccaguccu gcuacguugc cguggcuaga gccggaggca      120

uugagaccau cgcgaacgaa uauucugauc gguguacacc cgcuugcauu agcuuugggc      180

cuaagaaucg cuccaucgga gccgccgcua aaucucaagu gauuagcaac gccaagaaua      240

cgguccaggg cuucaaaaga uuucacgggc gggcuuucuc cgacccguuu guggaggccg      300

aaaagucuaa ccucgcguac gauaucguuc agcugcccac cggacuuaca ggcaucaaag      360

ugaccuauau ggaggaagaa cgcaauuuca caaccgagca ggucacagcc augcugcuca      420

gcaagcugaa ggaaaccgcu gaguccgugc uuaaaaagcc uguuguggac ugugucguga      480

gcgugcccug cuuuuacacg gaugccgaaa gacggucugu cauggacgcu acccaaauug      540

ccggccugaa cugucuccgc cugaugaaug agacaaccgc gguugcccug gcuuauggga      600

ucuacaaaca ggaucucccu gcccuggagg aaaagcccag aaacguggug uucgucgaca      660

ugggacauuc cgcuuaucag gugagcguuu gcgccuuuaa ucggggcaaa cuuaaggugc      720

uggccacagc uuucgauacc acgcucgggg gacgcaaguu ugacgagguc cuggugaacc      780

acuucuguga agaguuuggc aaaaaguaca aacuugauau uaagucuaaa aucagagcgc      840

ugcuccggcu gucccaggaa ugcgagaagc ugaaaaagcu caugagcgcc aaugcuucug      900

accugccucu uuccauugag uguuucauga acgauguuga cgugagcggg acaaugaauc      960

gcggaaaguu ccuggaaaug ugcaacgacc uccuggccag agucgagccg ccccuucggu     1020

ccgugcugga acaaaccaaa cucaagaaag aggauaucua cgccgucgaa auugugggcg     1080

gcgcuacacg caucccugcc guuaaggaga aaaucucuaa guuuuucggg aaggagcuga     1140

gcaccacccu gaaugcggac gaagcuguga caagaggaug ugcccuccag ugcgccauuc     1200

ugucccccgc uuuuaaaguc cgggaguuca gcaucacgga ugugguuccu uaucccauuu     1260

cucuuagaug gaacuccccg gccgaagagg gcagcucuga cugcgaagug uuuagcaaga     1320

accaugcugc cccuuucucc aaaguccuga ccuuuuaccg caaggagccc uucacacucg     1380

aggcguauua cucuagcccu caggaucugc ccuaucccga cccugccauc gcucaguuuu     1440

ccgugcaaaa agugaccccg cagagcgaug ggucuuccag caagguuaag gucaaagugc     1500

gggugaaugu ccacggaauu uucucugugu ccagcgccuc ccuuguugaa gugcauaagu     1560

cugaggaaaa cgaggagccc auggaaacag accagaaugc uaaagaggaa gagaagaugc     1620

aagucgauca ggaggagccu cacguggagg aacagcagca acagaccccc gccgagaaca     1680

aagcggaaag cgaggaaaug gagacguccc aggccggcuc uaaggacaag aaaauggauc     1740

agccucccca agcuaagaaa gccaagguua aaacaagcac cguggaccug ccgaucgaga     1800

aucagcuccu guggcagauc gacagagaaa ugcugaaccu cuacauugag aaugaaggga     1860

agaugaucau gcaggauaaa cuggagaagg aacgcaacga cgcuaagaau gccgucgagg     1920

aguaugugua cgaaaugcgg gauaaacuuu ccggagagua cgaaaaguuu guuagcgagg     1980

acgauagaaa cucuuucacc cugaaacucg aggacacaga aaauuggcug uaugaggaug     2040

gcgaagacca accuaaacag guguacgucg auaagcuggc cgagcuuaag aaccucggcc     2100

agcccauuaa gauccgcuuu caggaauccg aggagcggcc uaaacuguuc gaggaacugg     2160

ggaagcaaau ucagcaguau augaaaauca ucagcucuuu caagaauaaa gaagaccaau     2220

acgaucaccu cgacgcugcg gauaugacca agguggagaa guccacaaac gaagccaugg     2280

aguggaugaa uaacaaacug aaccuucaga auaagcagag ccugacgaug gaccccgugg     2340

ucaaaucuaa ggagauugaa gcuaaaauca aggagcucac cagcacaugu uccccuauua     2400

ucagcaagcc caaaccgaag guugaaccuc ccaaagagga acagaagaac gccgagcaaa     2460

auggacccgu ggacggccag ggggauaacc cuggaccgca ggccgcugag cagggcaccg     2520

acacagccgu gcccucugau uccgacaaaa agcugccuga aauggauauu gacugaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  3110
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt5)

<400>  3110
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggucggcau cgaccugggg uuccucaacu gcuacauugc cguugcuaga uccggaggca      120

ucgagaccau ugccaaugaa uauucugauc gguguacacc cgcgugcauc agccuggggu      180

cccgcacgag agcuauugga aacgccgcca agucucagau cgugaccaau gugcggaaca      240

caauccacgg cuuuaaaaag cugcaugggc gcagcuucga cgauccuauu guccaaaccg      300

agagaauccg gcuuccguac gaacuccaga aaaugcccaa uggauccgcu ggcgugaagg      360

uucgcuaucu ggaggaagag agaccuuuug ccauugaaca ggugacaggc augcuucugg      420

cuaaacucaa ggagaccucu gagaacgccc ugaagaaacc cgucgcggac ugugugauca      480

gcauuccuuc cuucuuuaca gaugccgaac ggcgcagcgu uauggcugcc gcucaggugg      540

ccgggcugaa uugccucaga cugaugaacg agaccacggc ggucgcccuu gcuuacggaa      600

ucuauaagca agaccugccc ccucucgaug agaaaccgcg gaauguggug uucauugaca      660

ugggccacuc ugccuaccag guccugguuu gugcuuuuaa caaggggaaa cuuaaggugc      720

uggccaccac auucgauccc uaucucggag gccgcaauuu ugacgaagcc cugguggauu      780

acuucugcga cgaguuuaag accaaauaca agaucaacgu caaagaaaau uccagagcuc      840

ugcuccggcu guaucaggag ugugaaaaac uuaagaagcu gaugagcgcg aacgccucug      900

aucucccucu gaauaucgag ugcuucauga acgaccuuga cguguccagc aaaaugaacc      960

gcgcucaguu ugagcaacug ugugccucuc uccuggccag aguugaaccc ccucugaagg     1020

cugugaugga gcaggccaau cuccagcggg aagauauuuc cagcaucgag auugucgggg     1080

gagcgacaag aauccccgcu gugaaggaac agauuaccaa auucuuccug aaggacaucu     1140

ccacgacacu uaacgccgau gaggccguug cucgcggcug cgcccugcaa ugugcuaucc     1200

ucucuccggc cuuuaaagug cgggaguuca gcauuaccga ccuggucccu uacuccauca     1260

cacuuagaug gaagaccagc uuugaagaug gcucugggga gugcgaagug uucugcaaaa     1320

aucaucccgc gccuuuuucc aaggucauua ccuuccacaa gaaagagccc uuugaacugg     1380

aggccuucua uacaaaccuc caugaggugc ccuacccuga cgcucgcauc ggcagcuuua     1440

cgauucagaa uguuuucccg cagucugaug gagacagcuc caaggugaaa gucaaggugc     1500

ggguuaacau ccacgggauc uuuucugugg ccagcgcuuc cgucauugaa aaacaaaauc     1560

uggagggaga ucacagcgac gcccccaugg aaaccgagac aucuuucaag aacgagaaua     1620

aggauaacau ggacaaaaug caaguggacc aggaagaggg ccaucagaag ugucacgcgg     1680

aacauacccc ugaggaagag aucgaucaca caggggccaa aaccaagucc gcugugagcg     1740

acaaacagga uagacugaau cagacgcuca agaagggaaa aguuaagucu auugaccugc     1800

ccauccaguc cagccuuugc cgccagcugg gccaagaucu ccugaacucc uauauugaga     1860

augaaggcaa aaugaucaug caggacaagc uggagaaaga acggaacgau gccaagaaug     1920

cugucgagga auacguguau gacuuuagag aucgccuugg gacaguguac gagaaauuca     1980

uuaccccuga ggaccucucu aagcugagcg ccguccugga agauaccgag aacuggcucu     2040

acgaagacgg agaggaucag cccaaacagg uguauguuga caagcugcaa gaacuuaaga     2100

aauacggcca gccgauccag augaaguaua uggagcacga ggaacggccu aaagcccuga     2160

acgaccucgg gaagaagauc cagcugguga ugaaagucau ugaggcuuac agaaauaagg     2220

augaacgcua ugaccaucug gaucccacag agauggagaa aguggaaaag uguaucuccg     2280

acgcgauguc uuggcuuaac agcaaaauga augcccaaaa caagcucucc cugacccagg     2340

auccuguugu gaaggucagc gagauugugg cuaaaucuaa ggaacuggac aauuucugca     2400

accccaucau uuacaaaccu aagcccaaag ccgagguucc ggaagauaag ccuaaggcca     2460

auuccgagca caacggaccc auggacggcc agagcgggac agagacgaaa ucugauucca     2520

ccaaggacag cucucaacau acaaaaagcu ccggcgaaau ggagguggau ugaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  3111
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt5)

<400>  3111
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ugagccucgu ggccgcuaug cugcuucugc ucuccgccgc gagagcugag gaagaggaca      120

aaaaggaaga ugucggcacc guugugggga ucgaccuggg aacaacguac ucuugcgugg      180

gcgucuucaa aaacgggcgg guggagauua ucgccaauga ucagggaaac cgcauuaccc      240

ccagcuaugu ugccuuuaca ccugaaggcg agagacuuau cggggacgcu gccaagaauc      300

aacugaccuc caacccggag aauacagugu ucgaugcuaa acggcucauu ggacgcaccu      360

ggaacgaccc cucuguccag caggauauca aguuucugcc uuucaaggug guugaaaaga      420

agacaaaacc cuacauccag guggacauug gcggcgggca aaccaagacg uuugccccug      480

aggaaaucag cgcgaugguc cugaccaaaa ugaaggagac agccgaggcu uaucucggaa      540

agaaagugac ccacgccgug gucacaguuc ccgcuuacuu caaugaugcc cagagacagg      600

cgaccaagga cgccggcacg auugcugggc ugaacgugau gcggaucauu aaugaaccua      660

cagccgcugc caucgccuau ggacuugaua aacgcgaggg cgaaaagaac auucuggugu      720

uugaccucgg gggaggcacc uucgaugucu cccugcuuac aaucgacaau ggcguguuug      780

agguuguggc uaccaacggg gacacccauc ugggaggcga agauuucgac cagagaguca      840

uggagcacuu uaucaaacuc uacaagaaaa agacagggaa ggaugugcgg aaagacaauc      900

gcgcgguuca aaagcugaga cgggaggugg aaaaagccaa gcgcgcucug ucuagccagc      960

aucaggccag aauugagauc gaauccuucu augagggaga agauuuuagc gagacgcuca     1020

cccgggccaa auucgaggaa cugaacaugg accuuuuccg cucuacaaug aagccggucc     1080

agaaggugcu ggaggauucc gaccucaaaa agagcgauau ugacgaaauc guccuggugg     1140

gcgggucuac ccggauuccc aaaauccaac agcuuguuaa ggaguuuuuc aauggaaaag     1200

aaccuuccag aggcaucaac cccgaugagg cuguggccua cggcgcggcu guccaggccg     1260

gggugcugag cggagaccaa gacacaggcg aucucguucu gcuggacgug uguccucuca     1320

cccuggggau ugagacgguc ggaggcguga ugacaaaacu uauccccaga aacaccgugg     1380

uuccgaccaa gaaaucucag aucuuuucca cagccagcga uaaucagccu accgucacaa     1440

uuaaggugua cgaaggggag cgcccccuga cgaaagacaa ccaccuccug ggcaccuucg     1500

aucuuacagg cauuccuccc gcuccccggg gagugccuca gaucgaaguc accuuugaga     1560

ucgacgugaa ugggauucug agaguuacag ccgaggauaa gggaaccggc aacaaaaaua     1620

agaucacgau uaccaacgac caaaaucgcc ucacaccgga agagaucgaa cggaugguga     1680

acgaugcuga gaaguucgcc gaagaggaca aaaagcugaa agagagaauu gauacccgca     1740

augaacugga guccuaugcg uacucucuca agaaccagau cggggacaaa gaaaagcugg     1800

gaggcaaacu uagcuccgag gauaaggaaa caauggagaa ggccgucgag gagaaaauug     1860

aauggcugga aagccaucag gacgcugaca ucgaggauuu uaaggccaaa aagaaagaac     1920

ucgaggagau cgugcagccc auuaucucua agcuguaugg guccgcuggc ccucccccua     1980

ccggagaaga ggacacggcc gaaaaggaug agcugugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  3112
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt5)

<400>  3112
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

cccccagaga gcuggcugug ggcaucgacc ucgggaccac auacagcugc gucggaguuu      120

uccaacaggg ccggguggaa auucuggcca acgaucaggg gaaucgcacg accccuuccu      180

auguggcguu uacagacacc gagagacuug ucggagaugc ugccaagucu caggccgcuc      240

ugaacccgca caauacagug uucgacgcca aacggcucau cggccgcaag uuugcugaua      300

ccacaguuca aagcgacaug aaacauuggc ccuucagagu ggucuccgaa gggggaaagc      360

cuaaagugcg gguuuguuac cgcggcgagg auaagaccuu uuaucccgaa gagauuucua      420

gcauggugcu guccaagaug aaagagacgg ccgaagcgua ccuuggccag ccugucaagc      480

acgccgugau caccgugccc gcuuauuuca acgacucuca gagacaggcc acaaaagaug      540

cuggggccau ugcgggacug aauguccucc ggaucaucaa cgagccuacc gccgcugcca      600

uugcuuacgg ccuggaccgc agaggggccg gagaacggaa uguucugauc uuugaucucg      660

gcgggggaac auucgacgug agcgugcugu ccauugaugc cggcgucuuu gaggugaagg      720

cuaccgcggg cgacacgcau cuugggggag aggacuucga uaaccgccug guuaaucacu      780

uuauggaaga guucagacgg aaacauggca aggaccucag cgggaacaag cgcgcccuga      840

gacggcuuag aacagcuugc gaacgcgcca aacggacccu gucuuccagc acacaagcca      900

cccucgagau cgauucucug uuugaaggag uggacuucua uaccuccauu acaagagcuc      960

gcuucgagga gcuguguagc gaucucuuuc ggucuacgcu ggaaccgguc gagaaggccc     1020

uuagagacgc gaaacuggau aaggcucaga uccacgacgu gguucucgug ggcgggucca     1080

cccgcauucc caaaguccag aagcugcuuc aggauuucuu uaauggaaaa gaacugaaca     1140

agagcaucaa uccugacgag gccguggccu acggcgcugc cguccaagcu gccgugcuca     1200

ugggcgauaa gugcgaaaaa guucaggacc ugcugcuccu ggacguggcg ccccuuuccc     1260

uggggcucga gacagccgga ggcgucauga ccacacugau ccagcggaac gcuaccauuc     1320

cuacgaagca aacacagacc uucaccacau acucugauaa ucagcccggg guguuuaucc     1380

agguuuauga gggagaaaga gccaugacca aagacaacaa ccuucugggc cgcuucgagc     1440

ucagcgggau uccgccugcu ccccggggcg ugccucaaau cgaagucaca uuugauauug     1500

acgccaaugg aauccugucc gugacggcga ccgauagaag cacaggcaag gccaacaaaa     1560

ucaccauuac aaaugacaag gggcgccugu cuaaggagga aguggagcgg augguucacg     1620

aggcugaaca guacaaagcc gaggaugaag cucagagaga ccgggucgcc gccaagaacu     1680

cccucgaggc ucauguguuc cacgugaaag gaagccugca ggaggaaucu cuucgcgaua     1740

agauccccga ggaagacaga cggaaaaugc aagauaagug uagagagguc cuggcguggc     1800

ucgaacauaa ucagcuggcc gagaaggagg aauaugagca ccagaaacgc gaacuggagc     1860

agauuugccg gcccaucuuu agcagacuuu acggcgggcc uggagugccg ggcggguccu     1920

cuuguggcac ccaagcucgc cagggagacc ccagcacggg cccuauuauc gaagagguug     1980

auugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  3113
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt5)

<400>  3113
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

cccccagaga gcuggcugug ggcaucgacc ucgggaccac auacagcugc gucggaguuu      120

uccaacaggg ccggguggaa auucuggcca acgaucaggg gaaucgcacg accccuuccu      180

auguggcguu uacagacacc gagagacuug ucggagaugc ugccaagucu caggccgcuc      240

ugaacccgca caauacagug uucgacgcca aacggcucau cggccgcaag uuugcugaua      300

ccacaguuca aagcgacaug aaacauuggc ccuuccaggu ggucuccgaa gggggaaagc      360

cuaaagugag aguuuguuac cggggcgagg auaagaccuu uuaucccgaa gagauuucua      420

gcauggugcu guccaagaug aaagagacgg ccgaagcgua ccuuggccag ccugucaagc      480

acgccgugau caccgugccc acauauuucu cuaacagcca gcgccaagcu accaaagacg      540

ccggggcuau ugccggacug aagguccucc cuaucaucaa ugaggcgaca gccgcugcca      600

uugcuuacgg ccuggauaga cgcggggccg gaaaacggaa cguucugauc uuugaccucg      660

gcgggggaac cuucgaugug uccgugcuga gcauugacgc cggcgucuuu gaagugaagg      720

cuacggcggg cgauacacau cuugggggag aggacuucga caauagacug guuaaccacu      780

uuauggagga guuccggcgc aagcauggca aagaucucuc ugggaauaag agagcccugc      840

ggcgccuuag aaccgcuugc gagcgggcca aaagaacacc guccagcucu acccaggcca      900

cccuggaaau cgacucccuc uuugagggag uggauuucua uaagagcauu acacgcgcuc      960

gguucgaaga acuguguucu gaccuguuua gauccacgcu cgagcccguc gaaaaagccc     1020

ugcgcgaugc gaaacuugac aaggcucaga uccacgauuu cgugcugggc gggggacucc     1080

acagccaucc ucagggcgcc gagguugccg cuggccugcu ucaacggcag ggggccgaac     1140

aggagcacca acccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  3114
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt5)

<400>  3114
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagca       60

agggccccgc cguggggauc gaccugggaa ccacauacuc cugcgucggc guuuuccagc      120

acgggaaagu ggagauuauc gcuaacgauc aaggaaauag aacgaccccu ucuuaugugg      180

ccuuuacaga caccgaacgg cucauuggcg augcggcuaa gaaccagguc gccaugaauc      240

cgacaaacac cguguucgac gccaaacgcc ugaucgggag acgguuugau gacgcuguug      300

ugcagagcga uaugaagcau uggcccuuca uggucgugaa ugacgccgga cgcccuaaag      360

uucaggugga guacaagggc gaaacaaagu ccuuuuaucc cgaggaaguc ucuagcaugg      420

ugcuuaccaa aaugaaggag auugcugagg ccuaccuggg caaaacggug accaacgcgg      480

ucguuacagu gccugccuau uucaaugauu cccaaagaca ggcuaccaag gacgccggga      540

caaucgcugg acucaacgug cugcggauca uuaaugaacc caccgccgcg gccaucgcuu      600

acggccuuga uaaaaagguc ggggccgagc gcaacgugcu gauuuuugac cucggaggcg      660

ggacguucga uguuucuauc cugacaauug aagacggaau cuuugaggug aagucuaccg      720

cuggcgacac acaccugggc ggggaggauu ucgacaauag aauggucaac cauuuuauug      780

ccgaauuuaa acggaagcac aaaaaggaua ucuccgagaa uaaacgcgcc gugagacggc      840

uccgcaccgc uugugaaaga gcgaagcgga cccugagcag cuccacacag gccagcaucg      900

agauugacuc ucuuuaugaa ggaaucgauu uuuacacguc cauuacccgc gcuagauucg      960

aggagcugaa cgccgaccuc uuccggggca cacuggaucc uguugaaaaa gcccuuagag     1020

acgcuaagcu ggauaagagc cagauccaug acauugugcu cgucggggga ucuacccgca     1080

ucccgaaaau ccaaaagcug cugcaggauu ucuucaaugg caaagagcuc aacaagucca     1140

uuaaccccga cgaagccgug gcguacgggg cugccgucca ggccgcuauc cugagcggag     1200

acaaauccga gaaugugcag gaucuucugc uccuggacgu uacaccucuu ucucugggca     1260

uugaaaccgc cggcggggug augacggucc ucaucaagcg gaacacaacc auucccacca     1320

agcaaacaca gaccuuuaca acguauagcg auaaucagcc uggagugcug auccaaguuu     1380

acgagggcga gagagcuaug accaaagaca acaaucugcu cgggaaguuc gaacugacag     1440

gaaucccgcc cgccccucgc ggcgugcccc agauugaggu caccuuugau aucgacgcga     1500

acgggauucu uaaugugucc gccguggaua aaagcacagg caaggaaaac aaaaucacca     1560

uuacgaauga caagggacgg cugucuaagg aggauaucga aagaaugguu caggaggcug     1620

agaaauauaa ggccgaagac gagaaacagc gcgauaaggu cuccagcaaa aacucucucg     1680

aaagcuacgc uuucaauaug aaggccaccg uggaggacga gaagcugcaa ggcaaaauua     1740

acgaugaaga caagcagaaa auccuugaca agugcaauga gaucauuaac uggcuggaua     1800

aaaaucagac agcggaaaag gaggaauuug agcaccagca aaaagagcuc gaaaaggugu     1860

guaacccuau cauuaccaag cuguaucagu ccgccggggg aaugcccggc gggaugcccg     1920

gaggcuuccc ugggggcgga gcuccgcccu cuggcggggc cagcuccgga ccuacaaucg     1980

aggaagucga cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  3115
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt5)

<400>  3115
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauca       60

gcgccuccag agcugccgcg gcucggcugg ugggcgccgc cgcuucucgc gggcccaccg      120

ccgcuagaca ccaggacagc uggaacggac ucucccauga ggccuuccgg cuggucucuc      180

gcagagauua cgcgagcgaa gccauuaagg gcgcuguugu ggggaucgac cuuggaacaa      240

cgaauagcug cguggccguc auggagggca aacaagcuaa ggugcuggaa aacgccgagg      300

gggcgcggac cacaccuucu guuguggccu uuaccgcuga uggagaacgc cucgucggca      360

ugccggccaa aagacaggcu gugacaaauc ccaacaauac cuucuaugcc acaaagcggc      420

ugauuggccg cagauacgac gauccugagg uucagaaaga caucaagaac gugcccuuua      480

agauuguccg ggccagcaau ggggaugcuu ggguggaggc gcacggaaaa cuuuauuccc      540

cuagccagau cggcgccuuc gugcugauga agaugaaaga aaccgcugag aacuaccucg      600

ggcauacggc caagaaugcc gucaucaccg uucccgcuua uuuuaacgac ucucaacgcc      660

aggccacaaa agaugcggga cagauuuccg gccugaaugu gcugagagug aucaacgaac      720

cuaccgcugc cgcccucgcu uacgggcugg acaagagcga ggauaagguc auugccgugu      780

augaccuugg aggcggcaca uucgauaucu cuauucugga gauccagaaa gggguuuuug      840

aagugaaguc caccaaugga gacacguucc ucggcgggga ggacuuugau caagcucugc      900

uucggcacau ugucaaagag uucaagcgcg aaacaggagu ggaccugacc aaagauaaca      960

uggcccucca gagaguucgg gaagcggccg agaaggcuaa augugagcug uccucuuccg     1020

ugcagacaga caucaaucug ccguaccuca ccauggauag cuccggcccc aagcaucuga     1080

acaugaaacu uaccagagcc caguuugaag ggaucgucac agaccugauu cgccggacga     1140

ucgcuccuug ccaaaaggcc augcaggaug cggagguguc uaagagcgac auuggagaag     1200

ucauccucgu gggcggcaug accagaaugc ccaaaguuca gcaaacagug caggaucugu     1260

ucgggcgcgc cccuuccaag gcugucaacc ccgacgaggc cguggcuauu ggagccgcca     1320

uccagggcgg gguucuugcu ggagauguga ccgacguccu gcuccuggac gugacaccgc     1380

ugagccucgg caucgaaacc cugggcggcg uguuuacgaa acuuauuaau cggaacacaa     1440

ccaucccuac caagaagucu cagguuuucu ccacagcggc cgauggacaa acccaggucg     1500

agauuaaagu gugucagggc gagagagaaa uggcugggga caauaagcug cucggacagu     1560

ucacacugau cggcauuccc ccugcucccc gcggggugcc ccaaaucgag gucacguuug     1620

auaucgacgc caacggaauu gugcacguua gcgccaaaga uaagggcacc gggcgggaac     1680

agcagaucgu gauucagucu agcggcggac uuuccaaaga cgauaucgag aauaugguca     1740

agaacgccga aaaguacgcg gaggaggaca gacgcaaaaa ggaacgggug gaggcuguua     1800

auauggccga aggcauuauc cacgauacag agaccaaaau ggaggaguuc aaggaccaac     1860

ugccugccga ugaaugcaac aaacucaagg aagagauuuc uaagaugaga gaacugcugg     1920

cucgcaaaga cagcgagaca ggggagaaua uccggcaggc cgcguccagc cuccagcagg     1980

cuucucugaa acuuuuugaa auggccuaua agaagauggc cuccgagaga gaaggaagcg     2040

ggucuuccgg gaccggagag caaaaagaag aucagaagga ggagaaacag ugaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  3116
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt5)

<400>  3116
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaggaggc uggcgggagc gauggaccca gagaaaccgc cccuacaucc gcguacucua      120

gcccggcucg gucccugggc gacacgggga ucacaccccu cucuccuagc cacauuguga      180

acgauaccga cuccaauguc ucugagcagc agagcuuccu gguuguggug gccgucgauu      240

uuggaaccac auccagcggc uaugccuacu cuuucaccaa agaacccgag ugcauccaug      300

ugaugcgcag augggaaggg ggagacccug gcguuuccaa ccaaaagaca cccaccacga      360

uucuucugac cccugagcgg aaauuucaca gcuucggcua ugcugcccgc gauuuuuacc      420

augaccucga uccgaaugag gcuaagcagu ggcuguaucu ugaaaaauuc aagaugaagc      480

ugcacacaac cggggaccuc acaauggaua ccgaccugac ggccgcgaac ggcaaaaagg      540

ugaaagcccu ggagaucuuu gcuuacgccc uccaguauuu caaggaacaa gcucugaaag      600

agcuuucuga ucaggccgga uccgaguuug aaaauagcga cgucagaugg gugauuacag      660

uucccgcgau cuggaagcag ccugccaagc aguucaugcg gcaagcugcc uaccaggcug      720

ggcuggccuc ucccgagaac uccgaacagc ucaucauugc ccuggagccu gaagcugcga      780

gcaucuacug ucgcaaacuu agacugcauc agaugauuga gcucuccucu aaggccgcug      840

ugaauggaua uagcggcucc gacaccgucg gggccggauu uacacaagcc aaagagcaca      900

uccggcgcaa cagacagagc cggaccuucc ugguggaaaa ugugauuggc gagaucuggu      960

cugaacugga ggaaggcgau aaguacgucg uuguggacuc cgggggaggc accguggauc     1020

ucacagucca ccagauucgc cugcccgagg ggcaucuuaa agagcuguau aaggcuacgg     1080

gaggcccgua cgggagccuc ggaguggacu augaauuuga gaaacugcuu uacaagaucu     1140

ucggcgaaga uuucaucgag caauuuaaga uuaaaagacc ugccgcgugg guugaccuga     1200

ugaucgcuuu cgaaucucgg aagcgcgccg ccgcucccga uagaaccaac ccucucaaua     1260

uuacacugcc cuuuagcuuc aucgacuauu acaaaaaguu ucggggccac uccguggagc     1320

augcccugag aaaaucuaac gucgauuucg ugaaguggag cucccagggg augcuccgca     1380

ugagccccga cgcuaugaau gcccuguuua agccuaccau ugauucuauc aucgagcacc     1440

uucgggaccu guuccagaaa ccggaaguuu ccacagugaa guuucucuuc cuggucggag     1500

gcuuugcgga ggcuccccuu cugcagcaag ccgugcaggc cgcuuucggg gaccagugca     1560

gaauuaucau uccucaggau gucggacuca ccauccugaa aggcgccgug cuguuugggc     1620

ucgaccccgc gguuauuaag gugcgccgga gcccucugac guacggcguc ggagugcuua     1680

acagauaugu ugaaggcaaa caucccccgg agaagcugcu cgugaaggau gggacacgcu     1740

gguguaccga cgucuucgau aaauucaucu cugccgacca auccguggcu cugggagagc     1800

uggugaagcg gagcuacacc ccugccaaac ccucccagcu uguuaucguc auuaauaucu     1860

auucuagcga acacgauaac guguccuuua uuacagaccc uggcgugaag aaaugcggga     1920

cccucagacu ggaucugaca ggaacgucug gcaccgcugu ccccgcccgc cgggagaucc     1980

agacacucau gcaguucggg gacaccgaaa uuaaggccac agcuaucgau auugcgacca     2040

gcaaguccgu gaaaguuggc aucgacuuuc ugaacuacug aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  3117
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt5)

<400>  3117
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugg       60

ccgugcccga gaugggccuc caggggcugu acaucggaag cuccccugaa agaucuccgg      120

uccccagccc ucccggcucc ccucggaccc aagagucuug cgggauugcu ccccuuacac      180

cuagccaguc cccgaagccc gaaguucgcg ccccucagca ggcgucuuuc agcguggugg      240

ucgcuaucga cuuuggaacg accuccagcg gcuaugccuu cucuuuugcc uccgaucccg      300

aggcuauuca caugaugaga aaaugggaag ggggagaccc uggcguggcc caucaaaaga      360

cacccaccug ucugcuccug acaccggagg gcgcuuucca cagcuuuggg uacaccgccc      420

gggauuauua ccaugaccuu gauccugagg aagcgcgcga cuggcuguau uucgagaaau      480

uuaagaugaa aauccacucu gccacagauc ucacccugaa gacgcagcug gaagcuguua      540

acggaaagac caugcccgcc cucgaggugu ucgcucaugc ccugagauuu uuccgggagc      600

acgcgcuuca ggaacugcgc gagcaguccc cuagccuccc cgaaaaagac acagucagau      660

gggugcugac cguucccgcc auuuggaagc aaccugcuaa acaguuuaug cgggaggccg      720

cuuaccuugc cggccuggug ucucgcgaaa augccgagca gcuccugauc gcucuggagc      780

cggaagcggc cuccgucuau ugcagaaagc uccggcugca ccagcuucug gaucucagcg      840

ggcgcgcucc cggaggcggg agacugggag agcggcgcuc caucgacucu agcuucagac      900

aagcccggga acagcuuaga cgcucccggc auagcagaac auuucuggug gagucuggcg      960

ugggcgaacu cugggccgag augcaggcug gggaucgcua cgucguugcc gacuguggag     1020

gcgggaccgu ggaucugacg gugcaccaac uggagcagcc ucauggaaca cucaaagaac     1080

uguacaaggc guccggcggg cccuauggag cugucggcgu ggaccuugcc uucgagcagc     1140

ugcucugccg gauuuucggc gaagacuuua ucgccaccuu caagagacag cgcccugcug     1200

ccuggguuga ucugacaauu gcuuuugagg cccggaaaag aaccgcgggg ccccaccgcg     1260

ccggagcucu uaacaucagc cugccguucu cuuuuauuga cuucuaccgg aagcaaagag     1320

gccacaaugu ggaaaccgcc cuccgccgga gcuccgucaa cuuugugaaa uggucuagcc     1380

aggggaugcu gagaaugucc ugugaggcua ugaaugagcu guuccagccu acaguuagcg     1440

gaaucauuca gcauaucgaa gcccuccugg cgcggcccga ggugcaaggc gucaaacuuc     1500

uguuucucgu cgggggcuuc gccgaaucug cugugcugca gcacgccgug caggcugccc     1560

ugggagcccg cggccuuaga guuguggucc cucaugaugu ggggcucacg auccugaagg     1620

gagcuguucu guuuggccag gcgcccgggg ugguccgggu gagacgcucc ccucucaccu     1680

auggaguggg cguucugaac cgguucgucc ccgggagaca cccgccugag aaacuucugg     1740

ugcgcgacgg cagacggugg ugcacagaug uguuugagcg cuucgucgcc gcugaacaaa     1800

gcguggcccu cggagaggaa guuagacggu cuuacugucc cgcccgcccc ggccagagac     1860

gggugcugau uaaucuguau ugcugugcug ccgaggacgc gcgcuucauc accgauccug     1920

gggucagaaa gugcggagcu cuuucccucg aacuggagcc ggccgacugu ggccaggaua     1980

cagccggggc ucccccugga cggcgcgaga uuagagccgc gaugcaguuu ggcgacaccg     2040

aaaucaaggu gacggcuguu gaugugagca caaaccgguc cgucagagcc ucuauugacu     2100

uccugagcaa uugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  3118
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt5)

<400>  3118
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

gagagaugac cauccugggc agcgcugugc ucacacugcu ucuggccggg uaccucgcgc      120

agcaauaucu gccccuuccu acgccgaagg ucauuggaau cgaccugggc accacauacu      180

gcuccguugg gguguucuuu cccggaaccg gcaaagugaa ggucauuccu gaugaaaacg      240

ggcacaucuc uauucccagc augguguccu ucacagacaa ugauguuuau gugggauacg      300

agucugucga acucgcugac agcaacccuc agaauaccau cuaugaugcc aaacgguuua      360

ucggcaagau uuucacagcc gaggaacugg aggcugagau cggccgcuac cccuuuaaag      420

ugcugaacaa gaaugggaug guugaguucu ccgugaccuc uaacgaaacg auuaccguca      480

gcccugaaua ugugggaucc agacuccugc uuaagcugaa agagauggcc gaggcuuacc      540

ucggcaugcc gguggccaau gcggucauca gcguucccgc cgaauuugac cugaagcagc      600

ggaacucuac aauugaggcu gccaaucuug cugggcugaa aauccuccgc gugauuaacg      660

aaccuaccgc cgcggccaug gcuuacggac ugcauaaggc cgauguguuc cacguccugg      720

ugaucgaccu cggcggggga acacuggaug uuucccuucu gaauaaacag ggcggcaugu      780

uucucaccag agcuaugagc gggaacaaua agcugggagg ccaagacuuc aaccagcggc      840

uucugcagua ucucuacaag cagaucuauc aaacguacgg guuugugccc ucucgcaaag      900

aggaaauuca uagacugcgg caggccgucg agauggugaa gcugaaucuc acacugcacc      960

aguccgccca gcuuagcguu cugcucaccg uggaggaaca agaucgcaaa gagccucauu     1020

cuuccgacac agaacugccc aaggauaaac uuagcuccgc ugacgaccac agagucaacu     1080

cuggauucgg ccgggggcug agcgauaaga aauccggaga gagccaggug cucuuugaaa     1140

ccgagaucuc ucgcaagcug uucgacaccc ugaacgagga ucucuuccag aagauucugg     1200

ucccgaucca acaggugcuu aaagaaggcc accuggagaa gacagaaauu gacgagguug     1260

ugcucgucgg cggguccacg agaaucccuc ggauccgcca ggugauucag gaauuuuucg     1320

gaaaagaucc caauaccagc guugacccug aucuggcggu ggucacaggc guggccaucc     1380

aagcugggau ugacggaggc ucuuggcccc uucaggugag cgcccuggag auccccaaca     1440

agcaucucca gaaaaccaau uuuaacugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3119
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt5)

<400>  3119
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

cuaucggcgu ccaccugggg ugcaccagcg ccugugucgc gguuuacaag gacggcagag      120

cuggaguggu ggccaacgau gccggggacc gggucacacc cgcugugguu gccuauuccg      180

agaaugaaga gauuguggga cucgcugcca aacagucucg caucagaaac auuagcaaua      240

cggucaugaa ggugaaacaa auccugggcc gguccucuag cgauccucag gcgcagaagu      300

acauugccga auccaaaugc cuuguuaucg agaagaacgg gaagcugcgc uaugaaaucg      360

acaccggaga ggagacaaaa uucgugaauc cggaagaugu cgcuagacuc aucuuuucua      420

agaugaaaga gaccgcccau agcgugcugg gcuccgacgc uaacgaugug gucauuacag      480

uucccuucga cuuuggcgaa aagcagaaaa augcccuugg ggaggcggcc cgggcugccg      540

gauucaacgu gcugcgccuc auucacgagc cuagcgcugc ccugcuggcc uacggcaucg      600

ggcaagauuc ucccaccgga aaguccaaua uucucguguu uaagcugggc gggacaagcc      660

uuucucuguc cgucauggaa gugaacagcg gaaucuauag aguucucucu accaauacgg      720

acgauaacau uggcggcgcu cauuucaccg agacacuggc gcaguaccuu gccuccgaau      780

uucagcggag cuucaaacac gacgugcgcg ggaaugcuag agccaugaug aagcugacca      840

acuccgccga ggucgcuaaa cauucucuca gcacacuggg auccgccaau uguuuucugg      900

auagccucua ugaaggccag gacuucgacu gcaacguguc ucgggcgcgc uuugagcugc      960

uuuguucccc ucuguucaac aagugcaucg aggcuaucag agggcuccug gaucaaaaug     1020

gauuuaccgc cgacgauauu aacaaaguug ugcuuugugg cgggagcucu cggaucccca     1080

agcugcagca gcucauuaaa gaccuguucc cugccgucga acugcucaau agcaucccgc     1140

ccgaugaggu gauuccuauc ggagcugcca ucgaagcugg cauucugauc ggcaaggaga     1200

accuucuggu cgaagacucc cucaugauug agugcucugc ccgcgauauc cuggugaagg     1260

ggguugacga gagcggagcg uccagauuca cggugcuuuu ucccagcggc acaccucugc     1320

ccgcccggag acagcacacc cuccaagcuc cggggucuau uuccagcguc ugucuggaac     1380

uguacgaguc ugauggcaaa aauuccgcca aggaagagac aaaauucgcu caggugguuc     1440

uccaggaccu ggauaagaaa gaaaacggac uucgcgacau ccuggccgug cucaccauga     1500

agcgggacgg gagccugcac gugaccugca cagaucaaga gacgggcaag ugugaggcga     1560

ucuccauuga aaucgccucu ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  3120
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt5)

<400>  3120
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggucggccu ggacguuggg ucccagucuu gcuacaucgc cguggcuaga gccggaggca      120

uugagaccau cgcgaacgaa uuuagcgauc gguguacacc cuccgugauu ucuuuuggga      180

gcaagaaucg cacgaucgga gucgcugcca aaaaccaaca gauuacccac gccaauaaca      240

caguguccaa uuucaagaga uuucauggcc gggcuuucaa cgacccuuuu auccagaaag      300

agaaggaaaa ucucucuuau gaucugguuc cgcuuaaaaa cgggggagug ggcaucaagg      360

ucauguacau gggcgaggaa caccuguuca gcguggagca gauuaccgcc augcuccuga      420

caaaacuuaa agagaccgcu gaaaauuccc ugaagaaacc cguuacagac ugcgugauca      480

gcgucccuuc uuucuucacc gaugccgagc gcagauccgu gcucgacgcg gcccaaauug      540

uggggcugaa cugucugcgg cucaugaaug auaugacggc ugucgcccug aacuauggaa      600

ucuacaagca ggaccuuccc agccuggaug aaaaaccucg cauuguugug uuuguggaca      660

ugggccauuc ugcuuuccag gucuccgccu gcgcguuuaa uaaggggaag cucaaagugc      720

ugggaaccgc cuucgauccc uuucuuggcg ggaagaacuu cgacgagaaa cugguugagc      780

acuucugugc ugaauuuaag acaaaauaua agcucgaugc caaaagcaag aucagagcuc      840

ugcugcggcu cuaccaggag ugcgaaaagc ugaaaaagcu gaugucuucc aauagcaccg      900

accuuccucu caacauugag uguuucauga acgacaaaga uguguccgga aagaugaauc      960

gcucucaauu ugaggaacug ugcgccgagc uucugcagaa aaucgaaguc ccgcucuaua     1020

gccugcugga gcagacacau cucaaggugg aagacguuuc cgccguggag aucgucggcg     1080

gcgcuacccg gauucccgcg gugaaggaaa gaaucgccaa auucuuuggg aaggauauua     1140

gcacgacacu gaacgcugac gaggccgucg cccgcggaug ugcccuucag ugcgcuaucc     1200

ugucuccugc guucaaagug agagaguuuu ccguuaccga ugcugugccc uucccuauua     1260

gccucaucug gaaucacgac ucugaagaua cagagggcgu ccacgaagug uuuagccgga     1320

accaugccgc ccccuucucc aagguucuga ccuuucuucg cagagggccg uucgagcugg     1380

aggcuuuuua cucugacccu caaggagugc ccuacccuga agccaaaauc ggccgguucg     1440

ucgugcagaa ugugagcgcu cagaaggaug gggagaaguc cagaguuaaa gucaaggugc     1500

gcgugaacac ccacggaauu uucacaauca gcacggccuc uauggucgaa aaagugccca     1560

ccgaggaaaa ugagaugucc agcgaggcgg acauggaaug ucucaaccaa cggcccccug     1620

agaauccgga uacagacaag aacguucagc aggacaauuc ugaagccggc acccagcccc     1680

aagugcagac agaugcucag cagaccuccc aaagcccucc cuccccugag cugacgucug     1740

aagagaacaa aauucccgac gccgauaagg cuaaugagaa gaaagucgac cagccgccug     1800

aagccaagaa acccaagauc aaagugguua acguggagcu gccuauugaa gcgaaucucg     1860

ucuggcagcu gggcaaggau cuucugaaca uguauaucga gacagaaggg aaaaugauca     1920

ugcaggacaa gcucgagaag gagagaaacg augccaaaaa ugcuguggaa gaguacguuu     1980

augaauuucg cgacaagcug ugcggacccu acgagaaauu cauuugcgaa caagaucauc     2040

agaacuuucu gcggcuucuc accgagaccg aggacuggcu guaugaagag ggcgaagauc     2100

aggccaagca ggcuuacgug gacaaacugg aggagcucau gaagaucggg acaccuguca     2160

aggugagauu ccaagaagcc gaggaacgcc ccaaaauguu ugaggaacug ggacagcggc     2220

uucagcacua ugccaagauu gcugcggauu ucagaaauaa agacgagaag uacaaccaca     2280

ucgacgagag cgaaaugaaa aagguggaga aguccgucaa ugaaguuaug gaguggauga     2340

acaaugugau gaacgcccaa gcuaaaaagu cucuggauca ggacccggug guccgcgccc     2400

aggaaauuaa aaccaagauc aaagagcuca auaacacaug ugagccugug guuacgcagc     2460

ccaagcccaa gauugaaagc ccuaaacugg agcggacccc gaauggcccc aacaucgaua     2520

agaaagaaga ggaccuggaa gauaagaaua acuuuggggc cgagccuccc caucaaaaug     2580

gcgagugcua cccuaacgaa aagaacuccg ugaauaugga ccuugauuga ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  3121
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt5)

<400>  3121
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaggugag acggcagcgc cccagacggc gcgucugcug ggcucugguu gccgugcucc      120

uggcggaucu ucuggcucuc agcgacaccc uggccgugau guccgucgau cuuggcucug      180

agagcaugaa aguggccauc guuaagccug gggugccgau ggaaaucguc cugaacaaag      240

aguccagacg gaagacaccc gugaucguua cgcucaaaga aaaugagcgc uucuuuggag      300

acucugcugc cagcauggcu auuaagaacc cuaaggccac ccugagauac uuccaacauc      360

ugcucggcaa acaggcggau aauccccacg uggcccugua ucaggcucgg uuuccugaac      420

acgagcuuac auucgacccc cagcgccaaa ccguccauuu ucagaucucc ucucagcugc      480

aguucagccc ugaggaagug cucgggaugg ugcugaacua cuccagaagc cuugccgagg      540

auuuugcuga acaaccgauu aaggacgccg ucaucacagu ucccguguuc uuuaaucagg      600

cggagcggcg cgccgugcug caggcugcca gaauggcugg acucaaaguc cugcagcuga      660

ucaacgauaa uaccgccaca gcccucucuu auggcguguu ccggcgcaag gacauuaaca      720

ccacggcuca aaauaucaug uuuuacgaua ugggguccgg aagcaccguu uguacaauug      780

ugaccuauca gauggucaaa acaaaggagg cgggcaugca gccucaacug cagaucagag      840

gcgugggguu cgaccggacc cuuggaggcc uggaaaugga gcucagacug cgcgaacggc      900

uugccgggcu guuuaacgag cagagaaagg gacagcgcgc uaaagauguu cgggaaaauc      960

ccagagccau ggccaagcuc cugcgcgagg cuaaccggcu gaaaacggug cucucugcca     1020

augcggacca cauggcucaa auugagggcc ugauggacga ugucgacuuc aaggccaaag     1080

ugacaagagu cgaguucgag gaacuuugcg ccgaucuguu ugagcgcgug ccugggcccg     1140

uucagcaggc ucuccagucc gccgaaauga gccuggacga gaucgagcaa gugauucuug     1200

ucggaggcgc uacccgggug ccgagaguuc aggaagugcu gcucaaggcc gucggcaaag     1260

aggaacuggg gaagaacauc aaugcggaug aggccgcugc caugggagcu guguaccagg     1320

ccgcggcccu gucuaaggcu uucaaaguga agccuuuugu uguccgcgac gccguggugu     1380

aucccauccu cgucgaguuc acacgggagg uggaggaaga accuggcauu cauucccuga     1440

aacacaacaa gagaguucuu uuuagccgga uggggcccua cccccagcgc aaagugauca     1500

ccuucaacag auacucccac gauuuuaauu uccauauuaa cuauggagac cugggcuuuc     1560

ucgggccuga agaucugcgg gucuucggau cucaaaaucu gaccacagug aagcucaagg     1620

gcguuggcga cagcuuuaaa aaguacccgg auuaugaguc caaagggauc aaggcucacu     1680

ucaaccucga cgagagcgga gugcugucuc uggacagagu cgaauccgug uuugagacgc     1740

ucguugaaga uagcgccgag gaagagucua cccugacaaa acuuggcaau accauuagcu     1800

cccuguucgg gggaggcaca acccccgacg ccaaggagaa cgggacggau acagugcagg     1860

aagaggaaga gucuccugcu gaaggcagca aggacgagcc cggagagcag gucgaacuca     1920

aagaggaagc ggaggccccu guggaagaug gcucccagcc cccgccuccc gagccuaagg     1980

gggacgcuac ccccgaggga gaaaaagcca ccgagaagga aaauggcgau aaaagcgagg     2040

cccaaaagcc uucugagaag gcugaagccg ggcccgaggg aguggcgccg gcuccugaag     2100

gcgagaaaaa gcagaaaccc gcccgcaagc ggagaauggu cgaagagauc gggguugagc     2160

ugguggugcu ggaccuuccc gaucucccug aagacaaacu ggcccagucc guccaaaagc     2220

ugcaggaucu cacacugcgc gaccuugaga aacaggaaag agagaaggcu gccaacagcc     2280

uggaagcguu caucuuugag acccaggaua agcucuacca accggaguau caggaagugu     2340

cuacagagga acagcgggag gaaauuuccg gcaaacugag cgcugccucc acguggcugg     2400

aggacgaggg aguuggcgcc accacaguga ugcuuaagga aaaacucgcu gagcugcgca     2460

agcuguguca ggggcuuuuc uuuagagucg aagaacggaa aaaguggccc gagcgccugu     2520

cugcccuuga caaucugcuc aaccauagcu ccauguuccu gaagggagcu agacugaucc     2580

cugaaaugga ucaaauuuuu accgaggugg aaaugacaac ccuugagaaa guuaucaaug     2640

aaacgugggc cuggaagaac gcgacccucg ccgagcaggc uaaacugccc gccacagaga     2700

agccugugcu gcucucuaaa gacauugaag cuaagaugau ggcccuggau cgggaggucc     2760

aguaccuucu gaauaaggcc aaauucacca agccccgccc uagacccaaa gacaagaacg     2820

gcacacgggc ugaaccgccu cucaaugcga gcgccuccga ucagggggag aaagugauuc     2880

ccccugcugg acaaaccgaa gacgccgagc ccaucagcga gccggaaaag guugagacgg     2940

gcucugaacc uggggauaca gagccccugg aacugggcgg accuggcgcc gagcccgagc     3000

agaaggaaca guccaccggg caaaaacgcc cccuuaagaa cgacgagcug ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3122
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt5)

<400>  3122
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggaaaccca gacacaagac cagcccaugg aggaagagga aguggagacg uucgccuuuc      120

aggcugagau cgcccagcug augagccuca uuaucaacac cuucuacucc aauaaggaaa      180

uuuuucugag agagcuuauc ucuaacagcu ccgaugcgcu ggacaaaauu cgguaugaau      240

cucucacaga uccgagcaag cuggacuccg gcaaagagcu ucacaucaau cugaucccca      300

acaagcaaga ucgcacccuc acaauugucg acaccgggau cggaaugaca aaagcugauc      360

ugauuaauaa ccugggcacc aucgccaagu cugggacgaa ggccuucaug gaggcucucc      420

aggccggagc ugacauuagc augaucggcc aguuuggggu uggauucuac uccgccuauc      480

ugguggcgga aaaagugacc gucauuacaa agcauaauga ugacgagcag uacgccuggg      540

aaagcucugc uggcggcucc uuuaccguga gaacagauac cggggagccu augggacggg      600

gcacgaaagu uauccuucac cugaaggaag accaaacaga guaucucgag gaacgcagaa      660

ucaaagagau ugugaagaag cauagccagu ucaucgggua ccccauuacc cuguuugucg      720

aaaaagagcg ggauaaggaa gugucugacg acgaggccga ggaaaaagag gauaaggaag      780

aggaaaaaga gaaggaggaa aaagaguccg aagacaagcc ugagaucgag gauguuggaa      840

gcgacgaaga ggaagagaag aaagauggcg acaagaaaaa gaaaaagaag auuaaagaaa      900

aguauaucga ucaggaggag cuuaacaaaa caaagcccau cuggacccgc aauccugacg      960

auauuaccaa cgaagaguac ggggaguucu acaaaucucu gacaaaugac ugggaggauc     1020

accucgcugu gaagcauuuu uccgucgaag gacagcugga guucagagcc cugcucuuug     1080

ugccgcggcg cgcgcccuuc gaccuguucg agaacagaaa gaaaaagaau aacaucaaac     1140

uuuaugugcg gcgcgucuuu auuauggaca auugcgaaga acugaucccu gaauaccuca     1200

acuucauuag aggcguugug gauagcgagg accugccccu uaacaucucc cgggaaaugc     1260

ugcaacaguc uaagauccuc aaagugauuc gcaagaaucu ggucaagaaa ugucuggagc     1320

ucuuuacgga gcuggccgaa gauaaggaga acuauaaaaa guucuacgaa caguuuagca     1380

aaaauaucaa acuuggcauu cacgaggacu cccaaaacag aaagaagcug agcgagcucc     1440

ugcgguauua caccucugcu uccggggaug aaauggugag ccuuaaggac uauugcacaa     1500

gaaugaaaga gaaucagaag cacaucuacu acauuaccgg agaaacaaaa gaucagguug     1560

ccaacucugc uuucguggag cgccugcgga agcauggccu cgaagucauc uauaugauug     1620

agccuaucga cgaguacugu gugcagcaac ugaaagaauu ugaggggaag acccugguua     1680

gcgugacgaa ggaaggacuc gagcugcccg aagaugagga ggagaaaaag aaacaggaag     1740

aaaagaaaac aaaguucgag aaucuuugca agaucaugaa agacauucug gaaaagaaag     1800

ucgagaaggu ggucgugucc aacagacucg uuaccucucc guguugcauc gugaccagca     1860

cauauggcug gaccgccaau auggagcgca uuaugaaagc ccaggcucug cgggauaacu     1920

ccacaauggg guacauggcg gccaagaagc accuggaaau caauccugac cauagcauua     1980

ucgagacgcu uagacagaaa gcugaagccg auaagaacga caaaucuguc aaggaccucg     2040

ugauccugcu guaugagacc gcccuccugu ccagcggauu uucucuugag gauccccaaa     2100

cacacgcuaa ucgcauuuac cggaugauca aacugggccu cggcauugac gaagaugacc     2160

cuaccgccga ugacacaucc gcggcuguua ccgaggaaau gccuccccug gagggggaug     2220

acgauacgag cagaauggaa gagguggacu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  3123
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt5)

<400>  3123
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcuccaagcu ggauucuggc aaagggcucc acaucaaccu ggugcccaau aagcagaacc      120

aaacccuuac aauugucgac acgagaaucg gaaugaccaa aacagaucug auuaauaacc      180

ucggcaccgu uacaaagagc gggaccaaag ccuucaugga ggcucugcag gccgacgcgg      240

auaucuccau gauuggacau uuuggcgugg gguucuacuc ugcuuaucuu guggccaaga      300

aggucacagu gaucagcaaa cacaauaacg acgaacagua caccugggag uccucugccg      360

gaggcagcuu uacgguucgg accgaugaau gaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  3124
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt5)

<400>  3124
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggaagugca ccauggcgag gaagaggucg aaaccuucgc cuuucaggcu gagaucgccc      120

aacugaugag ccucauuauc aacacauucu acuccaauaa ggagauuuuu cugagagaac      180

uuaucucuaa cgcgagcgac gcucuggaua aaauucggua ugagucccuc acggacccuu      240

cuaagcugga uagcgggaaa gaacuuaaga ucgacaucau uccgaauccc caggagcgca      300

cccugacacu cguugauacc ggaaucggca ugacaaaagc cgaccugauu aacaaucugg      360

ggaccaucgc caaguccgga acaaaggcuu ucauggaggc ccuccaggcu ggcgccgaua      420

uuucuaugau cgggcaguuu ggagugggcu ucuacagcgc guaucuggug gccgaaaaag      480

ucgugguuau uaccaagcac aacgacgaug agcaauacgc uugggaaucc agcgccggcg      540

ggucuuuuac ggugagagcu gaccauggag agccuaucgg ccgggggacc aaagucaucc      600

uucaccugaa ggaagaucag acagaguauc ucgaggaacg cagagugaaa gagguuguga      660

agaagcauuc ccaguucauu ggauacccca ucacccugua ucuugaaaaa gagcgggaaa      720

aggagauuag cgacgaugag gccgaagagg aaaaaggcga gaaggaagag gaggacaaag      780

acgaugaaga gaagccuaaa aucgaagacg ucgggucuga ugaggaggac gauuccggaa      840

aggacaagaa aaagaaaaca aagaaaauua aggaaaagua caucgaucag gaggaacuga      900

auaaaaccaa gcccaucugg acgcgcaacc cugacgauau uacacaagag gaauacggcg      960

aguuuuauaa aagccucacc aaugacuggg aggaucaccu ggcggugaag cacuucucug     1020

uggaaggcca gcuggaguuu agagcccucc uguucauccc gcggcgcgcu cccuuugacc     1080

uuuucgaaaa caaaaagaag aaaaauaaca uuaagcugua cgucagacgg guuuucauca     1140

uggacuccug cgaugagcuc auuccugaau aucugaauuu uauccgcggg gugguggaca     1200

gcgaggaucu uccccugaac aucuccagag agaugcucca gcagucuaaa auucugaagg     1260

ucauccggaa aaauauugug aagaaguguc uggaacucuu cagcgagcug gccgaagaca     1320

aagagaacua caagaaauuu uaugaggcuu ucuccaagaa ccuuaaacug ggaauccaug     1380

aggauagcac aaaucgcaga cggcucucug agcugcuuag auaccacacc ucccaaagcg     1440

gcgacgaaau gaccucucug agcgaguaug uuucccgcau gaaggaaaca cagaaaucua     1500

uuuacuacau cacgggggag agcaaggaac agguggccaa cuccgccuuu gucgaacggg     1560

ugagaaagcg cggauucgag guuguguaua ugaccgaacc uauugaugag uacugcgucc     1620

aacagcucaa agaauuugac ggcaagagcc uggugucugu cacaaaagag gggcuggagc     1680

uccccgaaga ugaggaagag aagaaaaaga uggaagaguc caaggcuaaa uucgagaauc     1740

uguguaaacu uaugaaggaa auccuggaca agaaagugga gaagguuacc aucagcaacc     1800

ggcucguguc uuccccgugc uguauuguca caagcaccua uggauggacg gcgaauaugg     1860

aaagaaucau gaaggcccag gcucugcgcg auaacuccac aaugggcuac augauggcca     1920

aaaagcaucu ggagauuaau ccugaccacc ccaucgugga aacccuucgg cagaaagccg     1980

aggcugauaa gaacgacaaa gccguuaagg accucguggu ccugcuguuu gagaccgcgc     2040

uccugucuag cggcuucucc cuugaagauc cucaaacaca cucuaauaga auuuaucgca     2100

ugaucaagcu ggggcucgga aucgacgagg augaaguggc ugccgaggag cccaacgccg     2160

cugugcccga cgaaauuccu ccgcuggagg gcgaugaaga cgccagccgg auggaggaag     2220

uugauugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  3125
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt5)

<400>  3125
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagag       60

cccugugggu gcucggccug ugcugugucc uucugaccuu cgggagcguu cgggcugacg      120

augaggugga cguggaugga acagucgaag aggaccucgg caagucccgc gaagggucua      180

gaacggauga cgaggugguu cagcgggaag aggaggccau ccaacuggau ggacuuaacg      240

cgagccagau ucgcgaacug agagagaaau ccgaaaaguu ugcuuuccag gccgagguga      300

aucggaugau gaaacucauc auuaacucuc uguacaagaa uaaagagauc uuucugcgcg      360

aacucauuag caacgccucc gacgcucugg auaagaucag acuuaucucu cugaccgacg      420

agaaugcccu cagcggcaac gaagaacuga cagucaagau uaaaugcgau aaggagaaaa      480

aucuucugca cgugaccgac acagggguug gaaugacccg ggaggagcuc gugaagaacc      540

ugggcacaau cgcuaaaucc ggcaccagcg aguuccugaa uaagaugacg gaggcccagg      600

aagaugggca aucuaccucc gagcucauug gacaguuugg cgucggguuc uauagcgcgu      660

uucugguggc cgacaaggug aucgucacau cuaaacauaa caaugacacc cagcacauuu      720

gggaauccga uagcaacgag uucucuguua ucgcugaccc ccgcggaaau acacuuggca      780

gagggaccac gauuacacug gugcucaagg aggaagccuc cgauuaccug gagcuugaca      840

ccaucaaaaa ccuggugaag aaauauagcc aguuuaucaa uuucccuauu uacgucuggu      900

ccucuaagac agaaaccgug gaggaaccga uggaggagga agaggcugcc aaagaagaga      960

aggaggaaag cgaugacgag gcggccguug aagaggaaga ggaggaaaag aaacccaaga     1020

ccaaaaaggu ggagaaaaca gucugggauu gggaacucau gaacgacauc aagccuauuu     1080

ggcaacggcc cuccaaggag guggaagagg augaguauaa agccuuuuac aagagcuucu     1140

cuaaagaauc cgacgauccu auggcuuaua uccauuuuac ggcugaggga gaaguuaccu     1200

ucaagagcau ucuguucgug cccacaucug ccccucgcgg ccuguuugac gaguacggca     1260

gcaaaaaguc cgacuacauc aagcucuaug ucagacgggu guucaucacc gaugacuuuc     1320

acgauaugau gccgaaauac cugaacuucg ucaagggggu gguugacucu gaugaccuuc     1380

cccugaaugu gagccgcgaa acacuccagc agcauaaacu gcuuaagguc auucggaaaa     1440

agcuggugag aaagacccuc gauaugauca aaaagauugc cgacgauaaa uauaacgaca     1500

cguuuuggaa ggaguucgga acaaauauca aacugggcgu uauugaggau cacuccaaca     1560

gaacccgccu ggcuaagcuc cugcgguuuc agagcucuca ccauccuacc gacaucacau     1620

cccuugauca auacguggaa agaaugaaag agaagcagga caagaucuau uucauggcgg     1680

ggagcucucg caaagaagcc gaguccagcc ccuuugucga gcggcugcuc aagaaaggau     1740

acgaagugau uuaucugacc gagccugugg acgaauacug uauccaggcu cugcccgagu     1800

ucgauggcaa gagauuucaa aauguugcca aagaaggggu caaguucgac gaguccgaga     1860

agacaaaaga aucucgcgag gccguggaaa aggaguuuga accgcuucuc aacuggauga     1920

aagauaaggc ucugaaagac aagauugaga aggccguggu cagccagcgg cugacggagu     1980

ccccuugcgc gcucguggcu ucucaguacg gauggagcgg caauauggaa agaaucauga     2040

aagcccaggc cuaucaaacc ggcaaggaua uuuccacaaa cuacuaugcu agccagaaaa     2100

agaccuucga gaucaauccc cgccacccuc ugauucggga caugcuuaga cgcaucaaag     2160

aagaugagga cgauaagaca guucuggacc ucgccguggu ccuguucgaa accgcuacgc     2220

ugcggucugg guaccuucuc cccgauacca aggccuaugg agacagaauc gagcggaugc     2280

ugcgccuguc ccucaacauu gaucccgacg cgaaagugga ggaagaaccu gaagaggagc     2340

cggaagagac agccgaagac accacagagg auaccgaaca ggacgaggau gaggaaaugg     2400

acguuggcac ggaugaggaa gaggaaacag cuaaggagag caccgccgag aaagacgaac     2460

ugugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  3126
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt5)

<400>  3126
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

gagagcugcg ggcucuccug cuuuggggcc gcagacugcg gccccuccug cgcgccccug      120

cgcuugcugc cgugcccggg ggaaagccga uccugugccc uagacggacc acagcccagc      180

ucggcccccg cagaaacccu gcuuggagcc ugcaagccgg gcggcuguuc uccacgcaga      240

ccgcugaaga caaagaggaa ccccuccacu cuauuaucag cuccacagag ucuguccagg      300

gaagcaccuc caagcaugaa uuucaggccg agacaaagaa gcugcuugau auuguugcgc      360

gcucucugua cagcgagaaa gaaguguuca ucagagagcu cauuuccaau gccagcgacg      420

cucuggaaaa acuucggcac aagcuggugu cugauggcca agcccucccu gagauggaga      480

uccaucugca gaccaacgcu gaaaaaggga caaucaccau ucaggacacg ggaaucggca      540

ugacccagga ggaacugguc uccaaucucg gcacaauugc ccgcagcggg ucuaaggcgu      600

uucuggaugc ccuucaaaac caggcugagg ccuccagcaa aaucauugga caguucggcg      660

ugggguuuua uucugcuuuc augguugccg acagagugga agucuacucc cggagcgccg      720

cuccgggauc ccugggcuau caguggcucu cugaugggag cggaguguuu gagaucgcgg      780

aggccuccgg cguucgcacc ggcacaaaga uuaucaucca ccugaaaagc gacuguaagg      840

aguucucuuc cgaggcuaga gugcgggaug ucgugaccaa guacagcaau uuugugucuu      900

ucccccuuua ucugaacggg agacgcauga auacgcucca agccauuugg augauggacc      960

cuaaagaugu ccgggaaugg cagcaugagg aauuuuacag auauguugcc caggcucacg     1020

acaagccccg cuacacacug cacuacaaaa ccgaugcccc ucugaacauc cggagcauuu     1080

ucuaugugcc cgacaugaag ccguccaugu uugacguguc uagagagcuc ggaagcuccg     1140

ucgcgcugua cagccgcaaa gugcuuaucc aaacaaaggc uaccgauauu cugccuaaau     1200

ggcuccgguu caucagaggc guuguggacu cugaggauau cccccugaau cuuucccgcg     1260

aacugcucca ggagagcgcc cugauucgga agcugagaga cguccuccag cagcgccuga     1320

ucaaguucuu uauugaucaa ucuaaaaagg acgccgaaaa auaugcuaag uucuuugagg     1380

auuacgggcu uuucaugcgg gaaggaaucg ugaccgccac agagcaggag guuaaagaag     1440

acauugcuaa gcugcucaga uaugagucca gcgcccugcc uuccggccag cugacgucuc     1500

uuagcgaaua cgcgucccgg augcgcgccg ggaccagaaa caucuauuac cucugcgcuc     1560

ccaaucggca ucuggccgag cacucucccu acuaugaggc uaugaagaaa aaggauacag     1620

aagugcuguu uuguuucgag caguuugacg aacucacccu gcuucaucug agagaguucg     1680

auaaaaagaa acucaucagc gucgaaacag acauuguggu cgaccacuac aaggaggaga     1740

aguuugaaga ucgcuccccu gccgcggagu gccugagcga aaaagagacc gaagaacuga     1800

uggccuggau gcggaacgug cuuggaucua gaguuacgaa ugugaagguc acacuccgcc     1860

uggacaccca cccggcuaug gugaccguuc uggagauggg cgccgcuaga cauuuccucc     1920

ggaugcaaca gcuggccaaa acacaggagg aacgcgccca gcuucugcaa cccacccucg     1980

aaaucaaccc uagacacgcu cugauuaaga aacugaauca gcuucgggcg uccgagcccg     2040

gccucgccca gcugcuggug gaucagaucu augaaaacgc uaugauugcc gccgggcucg     2100

ucgacgaucc ucgcgcuaug gugggaagac ugaacgagcu ucuggugaag gcccucgagc     2160

ggcauugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  3127
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt5)

<400>  3127
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

agaucagcuc ccugcccacc cagcuuuuca aaugcuguuu uugcgacuuc cugaagguga      120

aaaugcacac aaugucuagc ucccaucucu uuuaccuggc ccucugucug cuuacguuca      180

ccucuagcgc uacagccggg ccugagaccc ugugcggagc ggaacucguc gaugcucugc      240

aauuuguuug uggcgacaga ggguucuauu uuaacaagcc gacaggauac ggcuccucua      300

gccggcgcgc uccccagacc gggauugugg augagugcug uuucagaucc ugcgaccugc      360

ggcgccucga aauguauugu gccccucuga aacccgccaa gagcgccaga ucugugcggg      420

cucagcgcca cacagauaug ccuaagaccc agaaagaggu ccaucuuaag aaugccucca      480

gaggaagcgc gggcaacaaa aauuaccgga ugugaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  3128
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt5)

<400>  3128
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

uccccauggg aaagagcaug cuggugcucc ugaccuuccu ugccuuugcu uccugcugua      120

uugccgcgua cagaccuucu gagacacugu gcgggggcga acucgucgac acgcugcagu      180

ucguuugugg ggaucgggga uuuuauuuca gccgcccggc uuccagagug ucucggcgca      240

gcagaggcau cguggaggaa ugcuguuuuc gguccugcga ccuugcccug cucgagaccu      300

acugugccac acccgcuaaa ucugaacgcg augucagcac cccucccaca gugcugccug      360

acaacuuccc cagauauccu guugggaagu uuuuccaaua cgauaccugg aaacagucca      420

cacagcggcu gcgcagagga cucccggccc ugcuucgggc ucgcagaggc cacgugcugg      480

ccaaggagcu cgaggcguuu cgggaagcca aacgccauag accccugauu gcccuuccua      540

cccaggaccc cgcucacggc ggggcuccuc ccgagauggc cagcaaucgg aagugaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  3129
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt5)

<400>  3129
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaca       60

gcuucuccac cucugccuuu ggccccgugg cuuucagccu ggggcuccug cuuguccugc      120

cugccgcguu uccggcuccc guuccucccg gagaggacuc caaggaugug gccgccccuc      180

acagacagcc ccucacaucu agcgaacgga ucgacaaaca aauucgcuac auccuggaug      240

gcauuuccgc ucuuagaaag gagacgugca auaaaucuaa caugugugaa agcuccaagg      300

aggcccuggc ugaaaauaac cucaaucugc cuaaaauggc cgagaaggac gggugcuucc      360

agagcggauu uaacgaggaa accugucugg ugaagaucau uacaggccuc cuggaguucg      420

aagucuaucu ugaguaccug cagaaucggu uugagucuuc cgaagaacag gcgcgcgccg      480

ugcaaaugag caccaaaguu cucauccagu uccugcagaa gaaagcuaag aaccuugaug      540

ccaucacaac cccggacccc acaaccaaug cuucucugcu cacgaaacug caggcccaaa      600

accaguggcu gcaggauaug accacacauc ucauucugag auccuuuaag gaguuccuuc      660

agagcucucu gcgggcgcuc cgccaaaugu gaggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  3130
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt5)

<400>  3130
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugcucuggcu gagaggcuuc cuucuggcca gcugcuggau cauugugcgg uccucuccua      120

ccccggggag cgagggacac uccgcugccc ccgacugucc uucuugcgcg cucgcugccc      180

ugcccaagga ugucccuaac agccagcccg aaaugguuga ggccgugaaa aagcauaucc      240

uuaauaugcu gcaccucaaa aagcgcccug acgugacaca accggucccc aaagcugccc      300

ugcugaacgc uauuagaaag cuccaugugg gcaagguugg ggaaaaugga uacguggaga      360

ucgaagauga cauuggccgg cgcgccgaga ugaacgagcu gauggaacag acguccgaga      420

ucaucaccuu ugcggaaucu gggacagcca gaaaaacccu ucacuucgag auuagcaagg      480

agggauccga ucugagcguc guggaacggg cugagguuug gcucuuucug aaagugccua      540

aggccaaucg cacaagaacc aaagucacaa uccggcuuuu ccagcagcaa aagcaucccc      600

agggcucucu ggacaccggc gaagaggcug aagagguggg gcucaaggga gagcgcuccg      660

aacugcugcu cagcgagaaa guggucgaug ccagaaaguc uacguggcac guuuuuccug      720

uguccagcuc uauucagcgg cugcuugacc agggcaaauc cagccuggau gugcgcaucg      780

cgugugaaca augccaggag uccggggccu cucucguccu gcuuggaaag aaaaagaaaa      840

aggaagagga gggcgaaggg aagaaaaagg gaggcggcga agggggagcu ggcgccgacg      900

aggagaaaga acagagccac agacccuucc ugaugcucca ggcucggcaa uccgaggauc      960

auccgcaccg cagacggaga cgcgggcugg agugugacgg aaaggugaac auuugcugua     1020

aaaagcaguu uuucguuagc uuuaaggaua ucggcuggaa ugacuggauu aucgccccuu     1080

cuggguauca ugccaacuac ugcgaaggag agugucccuc ccacaucgcu ggcaccagcg     1140

gcucuagccu guccuuccac ucuacaguga uuaaucauua ucggaugaga gggcacagcc     1200

cuuuugcgaa ccucaaaucc ugcugugucc ccaccaagcu gcgccccaug agcaugcuuu     1260

acuaugacga uggacagaau aucauuaaaa aggacaucca aaacaugauu guggaagagu     1320

gcggcugcuc uugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  3131
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt5)

<400>  3131
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacg       60

gccugcccgg gagagcccuc ggagcugccu gccugcuucu gcucgcggcu ggcuggcugg      120

ggccugaggc cuggggaagc ccgacacccc cucccacccc ugccgcuccc ccuccgcccc      180

cucccccugg cucccccggg ggaucucagg auacguguac cagcugcggc ggcuuccggc      240

gcccggagga acuugggaga guggacggag auuuucugga agccgucaag cggcacaucc      300

ucucccgccu gcaaaugaga ggccggccua acauuacaca ugcuguuccc aaagccgcga      360

uggugaccgc ccugcgcaag cuccacgcug ggaaagugag agaggacgga cgggucgaaa      420

ucccucaucu ggauggccac gccucucccg gggcugacgg acaggagcgc gugagcgaga      480

uuaucuccuu cgccgaaaca gauggccuug cgucuagcag aguucggcug uacuuuuuca      540

uuuccaauga gggcaaccag aaucucuuug ugguccaggc cagccugugg cuuuaucuga      600

agcuccugcc cuacgugcug gaaaaagggu cucgcagaaa gguucgggug aaggucuauu      660

uccaagagca gggacauggc gaccgcugga acauggugga gaaaagagug gaucucaagc      720

gguccgggug gcacaccuuu ccucugacag aagcuaucca ggcccuuuuc gagagaggag      780

aacgccggcu gaaucucgac guccagugug auagcugcca agagcuggcu guugugccgg      840

uguuugucga ccccggcgaa gagucucaca gaccuuucgu gguugugcag gcccgccuug      900

gggauucccg gcauagaauc cgcaaacggg gacuggagug ugacggcaga accaaccucu      960

gcugucgcca gcaguuuuuc auugacuuuc ggcugaucgg cuggaaugau uggauuaucg     1020

cccccacggg guacuaugga aacuacugcg aaggcagcug uccugcuuau cuggcggggg     1080

uccccggauc ugccuccagc uuccacaccg cugugguuaa ucaauacaga augcgcggcc     1140

ucaacccggg gacagucaau uccugcugua uuccuaccaa gcugucuaca augagcaugc     1200

uuuacuucga cgaugaguau aacaucguga aacgggacgu gcccaauaug auugucgaag     1260

agugcggcug cgccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  3132
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt5)

<400>  3132
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ugagagugcu ccugcuuacc gcucugacac ucugccacgg cuucaaccug gacacggaga      120

augccaugac cuuucaggaa aacgcgcggg gguucggaca aagcgugguu cagcuucagg      180

gcucccgcgu gguggucggg gcuccccagg agaucguggc cgccaaucaa agaggaucuc      240

uguaccagug ugauuauagc acaggcuccu gcgaaccuau ucggcuccag guuccggugg      300

aggcugucaa caugucucug gggcugagcc ucgccgcuac cacauccccu ccucagcugc      360

uugccugugg acccaccgug caucaaacau gcucugaaaa uaccuacguu aagggccugu      420

guuuucucuu cggcagcaac cugcgccagc agccucagaa auuucccgag gcgcuuagag      480

ggugcccuca agaggacucc gauaucgccu uccugauuga cggaagcggc ucuaucauuc      540

cgcacgauuu ucggcgcaug aaggaguucg uguccacggu cauggaacag cucaaaaaga      600

gcaaaacccu guuuucucug augcaguauu ccgaagaguu cagaauccau uuuacauuca      660

aggaguuuca aaauaacccc aauccucgga gccucgugaa gcccaucacc cagcugcuug      720

ggcgcacaca caccgcuacg ggaauuagaa aagugguccg ggaacuguuc aacaucacaa      780

auggcgcccg caagaacgcu uucaaaauuc ucguugugau caccgacggg gagaaguuug      840

gagauccucu gggcuacgaa gacgugauuc ccgaggccga uagagaaggc gucauccggu      900

augugauugg gguuggagac gcguuccgcu cugagaaauc cagacaggag cuuaauacaa      960

ucgccagcaa gccgccucgg gaucaugugu uucaggucaa caauuucgaa gcucugaaga     1020

ccauccaaaa ccagcucaga gagaaaauuu uugccaucga aggcacccag acaggguccu     1080

cuagcuccuu cgagcacgaa augagccagg agggauuuuc ugcugccauu acguccaacg     1140

gcccccugcu gagcaccgug gggucuuacg acugggccgg aggcguuuuc cucuauacaa     1200

gcaaggagaa auccaccuuu aucaauauga cacgcgugga uucugacaug aacgacgcuu     1260

accugggcua cgcggccgcu auuauccuuc ggaauagagu ccaaagccug gugcucgggg     1320

ccccucgcua ucagcacauc ggacuggucg ccauguuccg gcagaacacc ggcauguggg     1380

aauccaaugc uaacgugaag gggacgcaga uuggagccua cuuuggcgcg agccuuuguu     1440

cuguugaugu ggacuccaau gggagcacag aucugguccu caucggcgcu ccccauuauu     1500

acgagcaaac cagaggaggc caggugucug uuugcccccu gccucgcggg cgggccagau     1560

ggcaguguga cgccgugcug uauggagaac agggccaacc gugggggcgc uucggagcug     1620

cccucaccgu ccugggcgau gugaacgggg acaaacuuac agauguggcu auuggcgccc     1680

ccggagagga agacaaucgg ggcgcgguuu accuguuuca cgggaccucc ggaagcggca     1740

ucuccccuuc ucauagccag agaauugccg gguccaagcu cucuccccgc cugcaguauu     1800

ucggacaaag ccuguccggc gggcaggauc uuacaaugga cggccucguc gaucugacgg     1860

ugggagcuca gggccacgug cugcuccugc ggagccagcc uguccuuaga gugaaagcca     1920

ucauggaguu caacccccgg gagguugcuc gcaauguguu ugaaugcaac gaccaagucg     1980

ugaaggggaa ggaggccgga gaaguuagag ugugucugca cguccagaaa ucuacccggg     2040

acagacuccg cgagggccag auccaguccg ugguuacaua cgaucuggcg cuggacagcg     2100

ggcggccgca uucuagagcc guguucaaug agaccaagaa cuccacacgc agacaaaccc     2160

agguccuugg acucacgcag accugcgaaa cacugaaacu gcagcucccu aauugcauug     2220

aggaucccgu gagcccuauc gugcugcggc uuaacuuuuc ucuggucggc acaccccuca     2280

gcgcuuucgg gaaccugcgc ccuguucugg ccgaagacgc ucaaagacuu uuuaccgccc     2340

ucuuccccuu ugagaagaau uguggcaacg auaauauuug ccaggacgau cuguccauca     2400

ccuucagcuu uaugucucug gacugucucg uggugggagg cccgcgggag uucaacguca     2460

cggugacagu ucgcaaugau ggggaagacu ccuacagaac ccaggugaca uuuuucuuuc     2520

cucuggaucu uagcuaucgg aaagucucca cccugcaaaa ccagcgcucu cagagaagcu     2580

ggcggcucgc cugcgagucc gcuucuagca ccgaaguguc cggagcgcug aagucuacaa     2640

gcuguuccau uaaucacccc aucuuccccg agaacagcga aguuacguuc aauauuaccu     2700

uugacgugga uucuaaggcc ucccugggca acaaacuucu ccugaaggcu aaugucacaa     2760

gcgagaacaa uaugccucgc accaacaaaa cagaguucca gcuggaacuc ccggugaagu     2820

acgccguuua uauggugguc accucucaug ggguguccac gaaauaccug aauuuuacag     2880

ccagcgagaa caccucuaga gugaugcaac accaguauca ggucuccaac cuuggacagc     2940

ggagccugcc caucucccuc guuuuccugg ugccugugag acugaaucaa accgucaucu     3000

gggaccgccc ccaggugaca uuuagcgaaa accuuucuag cacaugccau accaaggagc     3060

ggcugccuuc ccacucugac uuccucgcug aacugagaaa ggcccccguu gugaauugua     3120

gcauugcggu cugccagcgc auccagugug auauucccuu uuucggcauc caagaggaau     3180

uuaacgcuac gcucaaaggc aaucuguccu ucgacuggua cauuaagacc ucucacaacc     3240

aucuucugau cgugagcaca gccgagaucc ucuuuaauga uuccguuuuc acccugcugc     3300

ccgggcaggg agccuucgug cggucucaga cagagaccaa agucgaaccg uuugaggugc     3360

cuaacccccu uccucugauu gucggcagcu ccgucggggg acuccugcuc cuggcucuua     3420

ucacggccgc gcuguauaag cucggcuucu uuaaaagaca guacaaggac augaugagcg     3480

aagggggacc cccgggcgcu gagccucaau gaggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  3133
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt5)

<400>  3133
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguuca       60

gccugaagac ccuccccuuu cugcuucugc uccacgugca gaucuccaaa gccuucccug      120

ucucuagcaa ggagaaaaac acaaagacgg uucaagacua ccuggaaaaa uuuuaucagc      180

uuccguccaa ucaguaccag ucuaccagaa agaacggcac aaaugugauu guggagaagc      240

ugaaagaaau gcaacgguuc uuugggcuca acgucaccgg aaagcccaau gaggaaacac      300

uggauaugau gaaaaagccu cgcugcggcg ugcccgacag cgggggauuc augcugaccc      360

cuggcaaccc caaaugggag agaacaaauc ucaccuaucg gauccgcaac uacacgccuc      420

agcuguccga ggcugaaguu gagagagcca uuaaggaugc guuugaacuu uggucugugg      480

cuagcccgcu gaucuucacc cggauuuccc agggggaggc cgacaucaau aucgccuuuu      540

aucagcgcga ucauggagac aacagccccu ucgauggccc uaauggcauu cucgcucacg      600

ccuuucaacc cgggcaggga aucggcgggg acgcucauuu cgaugccgag gaaacaugga      660

ccaacacauc ugcgaauuac aaccuguuuc uugucgccgc ucacgaguuc ggacauuccc      720

ugggccucgc ccacagcucu gacccugggg cucugaugua ucccaauuac gccuucagag      780

aaaccuccaa cuacagccug ccgcaggaug acauugaugg aauccaggcg auuuauggcc      840

ucucuuccaa cccuauccaa cccacgggcc cuagcacacc caagcccugu gacccuuccc      900

ugaccuuuga cgccauuaca acccuucggg gagagauccu guucuuuaaa gaucgcuacu      960

ucuggagacg gcacccgcag cuccagcgcg uggaaaugaa uuuuaucucu cuguucuggc     1020

ccagccuucc uaccgggauu caagcugccu augaggacuu ugauagagac cugaucuucc     1080

ucuuuaaggg caaccaguac ugggcucugu ccggguauga uauucugcag ggauacccca     1140

aagacaucag caauuauggc uucccuucuu ccguucaggc cauugaugcc gcuguguuuu     1200

accggagcaa gacauacuuc uuugucaacg accaauucug gcgcuaugau aaucagagac     1260

aguucaugga gcccggguac ccgaaaucua ucagcggagc guuuccuggc aucgaaucca     1320

agguggacgc cguguuccag caagagcacu uuuuccaugu cuuuucuggc ccccgguauu     1380

acgcuuucga ucucauugcc cagagaguua cgcgcguggc ccgggggaac aaauggcuga     1440

auugcagaua uggaugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  3134
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt5)

<400>  3134
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

uguggcagcc ccucgugcug guccuucugg uucucggcug cuguuucgcc gcuccuagac      120

aacggcaguc cacccuggug cuuuuuccgg gggaccugcg cacaaaccuc acggauagac      180

agcuggccga ggaauaccug uaucgguacg gauauacccg cguggcggag augagaggcg      240

aaucuaaaag ccucgggccc gcucugcuuc ugcuccagaa acaacugucc cuuccugaga      300

caggagaacu ggacucugcc acccucaagg ccaugcggac accccgcugc ggcgucccug      360

aucuggggag auuccagacc uuugagggag accugaaaug gcaccaucac aauaucacau      420

acuggauuca gaacuauagc gaggaucucc cccgggcugu gaucgacgau gccuucgcuc      480

gcgccuuugc gcuguggucc gccguuaccc cucuuacguu caccagagug uacucucggg      540

acgcugauau ugucauccag uuuggcgugg ccgaacaugg cgacggguau ccguucgaug      600

gaaaggacgg ccugcucgcu cacgccuuuc ccccugggcc cgggauucaa ggcgaugcgc      660

auuucgacga cgaugagcug uggagccuug ggaaaggagu uguggucccu acacgcuuug      720

gcaaugccga cggcgcugcc ugucacuucc ccuuuaucuu cgaagggaga uccuacagcg      780

cuugcaccac agauggacgg ucugacggcc ugccguggug uuccaccacg gccaacuacg      840

auacagacga ucgcuucggg uuuugcccua gcgagagacu cuauacccag gacggaaaug      900

ccgauggcaa gcccugucag uucccuuuua ucuuccaggg gcaaucuuac uccgcuugca      960

caaccgacgg acggagcgau ggcuauagau ggugugcgac cacagccaac uacgaccgcg     1020

acaagcuguu uggcuucugc cccacgcggg cugauucuac cgugauggga ggaaauuccg     1080

ccggcgagcu guguguguuu cccuucacau uucucgggaa agaauauagc acaugcaccu     1140

ccgagggaag aggcgacggg cgccuguggu gcgccaccac gucuaacuuc gauagcgaca     1200

agaaaugggg cuuuuguccu gaucagggau acucccuuuu ccuggucgcu gcccacgaau     1260

uuggccaugc gcucgggcug gaccacagcu cuguuccgga ggcucuuaug uaucccaugu     1320

accgguucac agaaggaccu ccccugcaua aggaugacgu gaauggcauu agacaccucu     1380

acgggccucg ccccgagccg gagccucggc ccccuaccac cacaacaccc cagccuaccg     1440

cgcccccgac ggugugcccu accggaccuc ccacagucca ccccuccgaa agaccgaccg     1500

ccggccccac agggccuccc agcgcuggcc cuaccggacc cccuacggcc ggccccucua     1560

ccgcuacaac cgugccgcug agcccuguug augacgccug uaacgugaau aucuucgaug     1620

cgauugccga gaucgggaac caacuguauc ucuuuaaaga cggaaaguac uggcgcuucu     1680

ccgaaggccg ggggucuaga ccccagggac cuuuucugau ugcugauaag uggcccgccc     1740

uuccgcgcaa acuggacagc gucuucgagg aacggcucuc caagaaacug uuuuucuuua     1800

gcggcagaca gguguggguu uauacagggg cuucugugcu gggcccucgg cgccuugaca     1860

agcucggacu gggcgccgau gucgcccagg ugaccggggc ccugagaucc ggacggggca     1920

aaaugcuccu guucagcggg agacgccuuu ggcgguuuga cgucaaggcu caaauggugg     1980

aucccagauc ugccuccgag guugaccgca uguucccugg agugccccug gauacgcaug     2040

acgucuuuca guacagagag aaggcuuauu ucugccagga ucgguuuuac uggcgcguga     2100

gcuccagauc ugaacucaau cagguugacc aagugggcua ugucacauac gauauccugc     2160

agugucccga ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  3135
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt5)

<400>  3135
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ccggcgugcu ggccgcuuuc cucuuucuga gcuggaccca uugcagagcc cuuccucugc      120

cguccggggg agacgaggau gaccucucug aagaggaucu gcaguucgcg gaacgguacc      180

uucgcagcua uuaccacccc acaaaccugg cuggcauccu caaggagaau gccgccuccu      240

cuaugacgga aagacugcgg gagaugcaga gcuuuuucgg gcuggagguc accggaaaac      300

ucgacgauaa cacacuggac guuaugaaga aaccucgcug uggcgugccc gauguggggg      360

aauauaaugu cuuuccuaga acccuuaagu gguccaaaau gaaccugaca uaccggauug      420

ugaauuauac ccccgacaug acacauucug agguugaaaa ggcuuucaag aaagccuuua      480

agguguggag cgaugucacc ccucucaacu ucacgcgccu gcacgacgga aucgcugaua      540

uuaugaucuc cuuuggcauu aaagagcaug gcgacuucua cccguuugau gggcccagcg      600

gacuucuggc ccacgcguuc ccucccggcc cuaauuaugg gggagacgcc cacuuugacg      660

augacgagac cuggacaucu uccagcaagg gcuacaaccu cuuccuggug gcugcccaug      720

aguucgggca cucucuggga cucgaucauu ccaaagaccc cggcgcucug auguuuccga      780

ucuacaccua uacaggcaag agccacuuca ugcuuccuga ugacgauguu caagggaucc      840

agucucugua cggacccggc gacgaggauc cuaaucccaa gcaccccaaa accccugaca      900

agugcgaucc gucccucagc cuggacgcca uuacgucccu uagaggggaa acaaugaucu      960

uuaaagaccg guucuuuugg cgccugcauc cccagcaagu ggaugcggaa cucuuccuga     1020

ccaagucuuu uuggccugaa cugcccaaca gaauugacgc cgcuuaugag cacccuagcc     1080

augaucucau cuucauuuuu cggggacgca aauucugggc ccugaauggc uacgacaucc     1140

uugaggggua ucccaagaaa auuuccgaac ugggacuccc gaaggagguc aagaaaauca     1200

gcgcugccgu gcacuuugaa gauacaggca agacccugcu uuucucuggc aaccaggugu     1260

ggagauacga cgauaccaau cauaucaugg acaaagauua uccucggcug auugaggaag     1320

acuuucccgg gaucggagau aaggucgacg ccguuuacga gaaaaacggc uacauuuauu     1380

ucuucaaugg gccuauccag uuugaguacu ccauuuggag caaccgcauc gugagaguga     1440

ugcccgcuaa cucuauccuc ugguguugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3136
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt5)

<400>  3136
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

cccccaacac aacggaagac uacgauacca caaccgaguu cgacuauggc gaugccacac      120

cuugccagaa ggugaaugaa agagcuuuug gggcccaacu gcucccgccc cuguacagcc      180

uugucuucgu uaucggacug gugggcaaca uucucguggu ccuggugcuu guucaguaua      240

aacggcugaa gaauaugacc uccaucuacc uccugaaccu ggcgauuucu gaccuccugu      300

uucuuuucac acugccuuuu uggaucgauu auaaacucaa ggacgauugg guguucgggg      360

acgcuaugug uaaaauucug agcggauuuu acuauaccgg ccuuuacucc gagaucuucu      420

uuaucauucu gcucacgauc gaucgcuacc uggccauugu ccacgccgug uucgcucuga      480

gagcccggac cguuacauuu ggggugauca ccucuauuau cauuugggcu cucgccaucc      540

uggcgagcau gcccggacuu uauuucucca agacacagug ggaauuuacc caucacacgu      600

gcucucugca uuucccucac gagagccucc gcgaguggaa gcuguuccag gcccuuaaac      660

ugaaucucuu uggccugguc cugccccucc uggugaugau cauuuguuac acaggcauca      720

uuaagauccu ucugagacgg ccuaacgaga aaaaguccaa agcugugcgc cucauuuucg      780

ucaucaugau caucuuuuuc cuguuuugga ccccguauaa ucuuacaauu cugauuagcg      840

uuuuccaaga cuuucucuuc acccaugaau gcgaacaguc uagacaccug gaucuggccg      900

uccaggugac cgaggugauc gcuuacacac acuguugcgu gaaccccguu auuuaugccu      960

uuguggggga gcgguuccgc aaguaccuca gacagcuguu ucaucggcgc gucgcggugc     1020

accuuguuaa guggcugccu uuccucuccg uggacagacu ggaacggguc agcucuacgu     1080

cccccagcac cggagagcau gaacugucug ccggcuuuug aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  3137
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt5)

<400>  3137
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagaa       60

cccuggccug ccuccugcuu cugggcugug gguaccucgc ucacgugcug gccgaggaag      120

cggagauccc ccgggaaguc auugagcgcc uugcuagaag ccagauccau uccauucggg      180

accugcaacg ccuccuggaa aucgauucug uuggaagcga ggacucccug gauacaucuc      240

ucagagccca cggcgugcau gccacgaagc acgugccuga gaaacggccg cugcccauuc      300

gcagaaagcg gagcaucgaa gaggcugucc cugccgugug caaaacccgc acaguuaucu      360

augaaauucc cagaucccag guggacccua ccucugcuaa cuuccuuauc uggcccccuu      420

gugucgaggu gaagcggugc acaggguguu gcaauaccag cuccguuaaa ugucagccga      480

gccgcgugca ucacagaucu gucaaggugg ccaaggugga guacguccgg aaaaagccca      540

aacugaagga aguucaggug cgccucgagg aacaccugga gugcgcgugu gccacaaccu      600

cccuuaaccc ugauuauaga gaagaggaca cgggacggcc cagagagagc ggcaaaaagc      660

gcaagcggaa aagacugaag ccuaccugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  3138
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt5)

<400>  3138
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaca       60

gaugcugggc ccuguuccuc agccuguguu gcuaccuucg gcuggugucc gcugagggcg      120

accccauccc ugaggaacuc uaugaaaugc ugucugauca cagcauucgc uccuuugacg      180

aucuucagag acugcuccau ggggacccgg gagaggaaga uggcgccgag cuggaccuga      240

auaugacccg gucucacagc gggggagagc ucgaaucccu ggcgcgcggc agacggucuc      300

uugggagccu gacaaucgcu gagcccgcca ugauugccga auguaagacg cgcaccgagg      360

ucuucgagau cuccagacgg cucauugauc gcacaaacgc uaauuuucug guuuggccuc      420

ccugcgugga agugcaaaga uguagcggau gcuguaacaa ucggaacguc cagugccgcc      480

cuacccaggu gcagcuuaga cccguucaag ugcggaaaau cgagaucguc cgcaagaaac      540

cuauuuucaa gaaagccaca gugacccugg aagaccaucu cgcuuguaag ugcgagacag      600

uugccgcggc cagaccggug acccggucuc ccggcggcuc ccaggaacag agagcuaaga      660

cgccucagac ccgcgucaca auccggaccg ugagagugcg ccggcccccu aaagggaagc      720

acagaaaauu uaagcauaca cacgauaaaa ccgcccugaa ggagacgcug ggagcuugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  3139
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt5)

<400>  3139
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

uguucggccu ccugcuucug accuccgccc ucgcugggca gagacaagga acacaggccg      120

agucuaaccu gagcuccaag uuucaguucu cuagcaauaa agaacagaac ggcgugcaag      180

acccccagca cgagcggauc auuacggucu ccaccaaugg gucuauccau agcccucgcu      240

uuccgcacac auaccccaga aacaccguuc uuguguggcg gcugguggcg gucgaagaga      300

auguguggau ucagcucaca uucgaugaac gcuuuggacu ggaggacccu gaggaugaca      360

ucugcaagua ugauuucguu gaaguggagg aacccuccga cggcaccauu cuggggagau      420

gguguggaag cggcacaguc ccuggcaaac agaucucuaa ggggaaccaa auccggauuc      480

gcuuuguguc cgaugaguac uuccccagcg agccuggauu uugcauccau uauaauauug      540

uuaugccgca guucaccgaa gcugugucuc ccuccguccu cccucccagc gcccugccuc      600

uugaccugcu caacaaugcc aucacggcuu uuucuacccu ggaggaucuu auuagauacc      660

uggaacccga gcgguggcag cucgaccugg aagaucugua ucgcccgaca uggcagcucc      720

ugggcaaagc cuucguguuu gggagaaagu cccggguggu cgaccuuaac cugcucaccg      780

aggagguucg ccuguacagc uguacaccua gaaauuucuc cgugucuauc cgggaggaac      840

uuaagcgcac cgauacgauu uucuggcccg gaugccugcu cgugaaaaga uguggcggga      900

acugcgcuug uugccugcac aauuguaacg aaugccaaug ugucccuagc aaggugacca      960

aaaaguauca ugagguucug cagcuccggc ccaaaacagg agugagaggc cugcacaagu     1020

cccuuacaga cgucgcccug gaacaccaug aggagugcga cugcgugugu cgcggcagca     1080

ccgggggaug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  3140
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt5)

<400>  3140
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gacugaucuu cguguacacc cucauuugcg ccaacuuuug uagcugccgg gacacauccg      120

cuacgcccca gucugccagc aucaaggcgc ugcgcaaugc uaaccuuaga cgggaugacc      180

uguaucgcag agaugagacc auucaaguca aaggcaaugg guacguucag uccccucggu      240

ucccgaacuc uuauccccgc aaucuccugc uuacauggag acugcauagc caggaaaaca      300

cccggaucca gcucguguuu gacaaucaau ucggacugga ggaagccgag aacgauauuu      360

gucgcuacga cuuuguggaa gucgaggaua ucuccgagac aucuaccauc auuagaggcc      420

gguggugcgg gcacaaggaa gugccucccc gcaucaaaag cagaacaaau cagauuaaga      480

ucaccuucaa auccgacgau uauuuuguug ccaagccugg auucaagauu uacuauagcc      540

ugcucgagga cuuucagccc gcugccgcuu cugaaacgaa cugggagucc gugaccagcu      600

cuaucuccgg cgucagcuac aauucuccuu ccgugacaga uccgacccug auugccgacg      660

cgcuugauaa aaagaucgcc gaguucgaca caguugaaga ccugcucaaa uacuuuaacc      720

ccgagagcug gcaggaagau cuggagaaua uguaucuuga caccccucgg uaccgcggga      780

gauccuauca ugaucggaag ucuaaagugg accuggauag acucaacgac gaugcuaagc      840

gcuacagcug uacgccccgg aauuauuccg ucaacaucag agaggaacug aagcuggcca      900

acgugguguu cuuuccucgc ugccuccugg uccaacggug uggaggcaau ugcggcugug      960

ggacaguuaa cuggagaagc ugcaccugua auucuggaaa aacagugaag aaauaccacg     1020

aggugcuuca guucgaaccc ggccauauua agcgccgggg gagagcuaaa accauggccc     1080

uggucgacau ccagcucgau caccacgagc gcugcgacug cauuuguucc agccggccgc     1140

cuagaugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  3141
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt5)

<400>  3141
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguga       60

cccacagcaa guuccccgcc gcuggcaugu ccagaccucu ggacacaucu cuccggcuga      120

aaacguuuag cuccaagucu gaguaccagc uugucguuaa cgccgugcgc aaacugcaag      180

aaagcggguu cuauuggucc gcggugaccg gaggcgaggc uaaucuccug cuuucugccg      240

aaccggccgg gacauuucug aucagagaua gcuccgacca gcggcauuuc uuuacccuca      300

gcgucaagac acagucugga accaaaaacc ugcgcauuca gugcgagggc ggguccuuca      360

gccugcaauc ugaucccaga uccacacagc cugugccccg guuugacugu guucucaagc      420

uggugcacca uuacaugccu cccccuggag cuccgagcuu ccccucuccu cccaccgaac      480

cuuccagcga gguccccgag cagccguccg cccagccucu ucccggcucu ccuccccgca      540

gagcuuauua caucuauagc ggcggggaaa agauuccccu ggugcucucc cggccucuga      600

gcucuaaugu ugccacgcuu caacaccugu gccgcaaaac cgugaacgga caucucgauu      660

ccuacgagaa ggucacacag cugccgggcc ccaucagaga auuucuggac caguaugaug      720

cgccucucug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  3142
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt5)

<400>  3142
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugc       60

ccagcgccgg ccagcuggcu cucuucgccc uggggaucgu ccuugcggcu ugccaagccc      120

uggagaacuc caccucuccu cucagcgccg acccgcccgu ugcugccgcu gugguguccc      180

acuuuaauga uuguccugac ucucauacac aguucugcuu ucacggaacg uguagauucc      240

ugguccagga agauaagccc gccugcgugu gucauagcgg cuacguuggg gcgcggugcg      300

agcacgccga ccuucuggcu guggucgccg cuucccagaa aaagcaagcc auuaccgcgc      360

ucgugguugu gucuaucguc gcccuggcug ugcugauuau cacaugugug cucauucauu      420

gcugucaggu ccgcaaacac ugcgaauggu guagagcccu gaucugccgg cacgagaagc      480

cuagcgcccu ucugaaagga cgcaccgcuu gcugucauuc cgaaacaguu gugugaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  3143
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt5)

<400>  3143
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

cuagcggccu gagacuccug ccgcuucugc ucccccugcu uuggcugcuc gugcugaccc      120

cugggcggcc cgccgcugga cuguccacau gcaagacgau cgacauggag cucgucaaac      180

gcaagagaau ugaagccauc cggggccaga uucugucuaa acuucgccug gcgagcccuc      240

ccucccaagg ggagguuccu ccgggacccc ucccugaagc ugugcuggcc cuuuacaacu      300

cuaccagaga ucggguggcc ggcgagagcg cugaacccga gccugagccc gaagccgacu      360

auuacgcuaa ggaggucaca cgcgugcuga ugguugaaac ccacaaugag aucuaugaua      420

aauucaagca guccacacau ucuauuuaca uguuuuucaa caccagcgag cucagagaag      480

ccgugccgga gccuguccug cugucccggg cggaacuccg ccugcuuaga cugaagcuca      540

aaguggagca gcacguugaa cuguaucaga aguacagcaa uaacucuugg cgguaucuuu      600

ccaaucgccu gcucgccccc agcgacucuc cugaguggcu guccuuugau gugacagggg      660

ucgugagaca auggcugagc cggggaggcg agaucgaagg cuuccgccuc ucugcucauu      720

guuccugcga cagcagagau aacacccuuc agguggacau caauggguuu acgaccggac      780

ggagaggcga ucuggccaca auucacggga ugaaccgccc cuuccugcuc cugauggcua      840

caccccuuga gcgggcccag caucugcagu ccucuagaca ccgccgggcg cucgacacca      900

auuacuguuu uagcuccacc gagaaaaacu gcugugucag acaacuguac aucgauuucc      960

gcaaggaccu gggauggaaa uggauucacg aaccuaaggg cuaucaugcc aauuuuugcc     1020

ucgggccgug ucccuacauc uggagccugg auacgcagua uucuaagguu cuugcucugu     1080

acaaccagca caauccugga gccuccgcug cccccugcug ugugccucag gcccucgaac     1140

cccugccgau uguguauuac gucggccgga aaccuaaggu ggagcaacug agcaacauga     1200

ucguuagauc uugcaaaugu agcugaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  3144
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt5)

<400>  3144
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugcgugcu gagcgccuuc cucauccugc aucuugucac cguugcucug ucccucucua      120

cauguagcac gcuggacaug gaucaguuua ugagaaagcg gauugaggcc auccgcggcc      180

aaauucuuuc caaacugaag cucaccucuc ccccugaaga cuauccggag cccgaagagg      240

ugccucccga agugaucagc auuuacaacu ccacaagaga ucugcugcag gagaaagcgu      300

cucggcgcgc ugccgccugc gagagagaac ggagcgacga ggaauauuac gcuaaggagg      360

ucuauaaaau cgauaugccu cccuucuuuc cuuccgagaa ugccaucccg cccaccuucu      420

accgcccuua uuuuagaauu gugcgguucg acguuagcgc uauggaaaag aacgccucua      480

aucucgugaa ggcggaguuu cgcgucuuca gacugcagaa ccccaaagcc cgggugccug      540

aacagcgcau cgagcuuuac caaauucuga aguccaaaga ucucacaagc cccacccaga      600

gauacaucga cucuaagguu gugaaaacac gggcugaagg ggaguggcug uccuuugaug      660

ucaccgacgc cgugcacgag uggcuucauc acaaggaucg caaucuggga uucaagauua      720

gccuccauug uccgugcugu acguuugugc cuucuaacaa uuauaucauu cccaacaaau      780

ccgaggaacu ggaagcuaga uucgccggca ucgacgggac cagcacauac accuccggag      840

aucagaagac aaucaaaucu acccggaaga aaaauagcgg caagacgccu caucugcucc      900

ugaugcuucu gcccuccuau agacucgaga gccagcaaac aaaccgccgg aaaaagagag      960

cgcuggacgc cgcuuacugc uuucgcaaug uccaggacaa cuguugccuu cggccccugu     1020

auauugauuu caagagagac cucgggugga aauggaucca cgaaccuaag ggauacaaug     1080

ccaacuucug ugcuggcgcc ugcccguauc uguggucuuc cgauacccag cacagccgcg     1140

uucugucucu cuacaauaca auuaaccccg aggccagcgc uuccccuugu ugcgugucuc     1200

aggaccugga gccccuuacc auccuguacu auauuggcaa aaccccuaag aucgaacaac     1260

ucagcaacau gaucgugaaa uccugcaagu guagcugagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  3145
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt5)

<400>  3145
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

ugcaccuuca gagagcccuc gugguccugg cucugcugaa cuucgccacc guuagccucu      120

cccugucuac augcacgacc cuugacuuug gccauaucaa aaagaaacgg guggaggcga      180

uucgcgggca aauccugagc aagcucagac ugacaucucc cccugaaccg accgugauga      240

cacacguccc cuaccaggug cuggcucucu auaauuccac ccgggagcug cuugaagaga      300

ugcauggaga acgcgaggag ggcuguacac aggaaaacac cgagagcgaa uacuaugcca      360

aagagauuca caaguucgau augauccagg ggcuggccga gcauaaugaa cucgcuguuu      420

gcccuaaggg aauuacgucc aaaguguuua gauucaacgu cucuagcgug gagaagaauc      480

ggaccaaccu guuucgcgcc gaguucagag uucuucgggu gcccaauccu uccagcaaac      540

gcaacgaaca aagaaucgaa cuguuucaga uccuccggcc cgacgagcac auugcuaagc      600

agcgcuacau cggcgggaaa aaucugccua caagaggaac cgccgagugg cugucuuucg      660

augucacaga caccgugcgg gaauggcucc ugcgcagaga guccaaccuu ggccuggaaa      720

uuagcaucca cuguccgugc cauacguuuc agcccaaugg cgauauucuc gagaacaucc      780

acgaagugau ggagauuaag uucaaggggg ucgacaauga ggaugaccau ggacggggcg      840

aucuggggag acuuaaaaag caaaaagacc accacaaccc ucaucugauc cucaugauga      900

uucccccuca ccgccuggau aaucccggac agggcgggca gcggaagaaa agagcgcugg      960

acacaaacua uuguuuucgc aaccucgaag agaauugcug uguucggccg cuguacaucg     1020

auuucagaca ggaccuugga uggaaguggg ugcaugaacc uaaaggcuau uacgccaacu     1080

uuugcucugg ccccuguccu uaccugcgcu ccgcugacac cacacacagc accgugcucg     1140

ggcuguauaa uacccuuaac cccgaggccu cugcuucccc cugcuguguc ccucaagauc     1200

uggaaccgcu cacaauccug uacuaugugg gacggacgcc caagguugag cagcugagca     1260

auaugguggu caaguccugc aaaugcucuu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3146
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt5)

<400>  3146
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ccguggcugu cugggccgcg cuggcuguug gccucgagcu gugggccgcc gcucacgccc      120

uuccugcuca gguggccuuc accccguacg cgcccgaacc ugggagcaca ugcagacugc      180

gggaguauua cgaccaaacg gcccagaugu guugcuccaa guguucuccc ggacagcaug      240

cuaaaguguu uugcaccaag acaagcgaua ccgucuguga cuccugcgaa gauucuacau      300

auacccagcu cuggaacugg gugccugagu gucugagcug cggcucccgc uguucuagcg      360

accaaguuga aacacaggcc ugcaccagag agcagaaucg gaucuguacg ugccgccccg      420

ggugguacug cgcucuuucc aaacaggagg gauguagacu gugcgccccu cuccggaagu      480

gucgcccggg cuucggggug gcgagacccg gaaccgaaac aagcgauguc gugugcaaac      540

cuugugcccc cggcaccuuu ucuaacacaa ccuccagcac ggacauuugc cggccucacc      600

aaaucuguaa uguuguggcu auucccggca acgccucuau ggaugcuguc ugcacaucca      660

ccagcccgac acgcucuaug gccccugggg ccgugcaucu gccccagccu guguccacca      720

gaagccagca cacccagccc acacccgagc cuuccacggc uccgucuacc agcuuccugc      780

uccccauggg accuuccccu cccgcggaag gcagcacagg ggacuuugcc cugcccgucg      840

gacuuaucgu uggcgugacc gcucuggggc uccugauuau cggagugguc aauuguguga      900

ucaugacaca aguuaagaag aaaccgcuuu gccugcagcg ggaggccaag gugccucauc      960

uccccgccga uaaagcucgc ggcacccagg gcccugagca acagcaucug cugauuacgg     1020

cccccucuuc cagcucuagc ucccucgaau cuagcgcguc cgcucuggac agacgggccc     1080

cuacacgcaa ccagccccag gccccggggg ucgaggcuag cggagccggc gaagcuagag     1140

ccucuaccgg guccagcgau ucuuccccug gaggccacgg gacccaagug aauguuacau     1200

guaucgugaa cgucugcagc uccucugacc acagcuccca gugcucuagc caggcgucca     1260

gcaccauggg agauacagac ucuuccccca gcgagucucc caaggacgaa caggugccuu     1320

ucuccaaaga ggagugugcc uuucggagcc aacuugaaac gccggagacc cugcucggcu     1380

cuacagaaga gaagccccug ccucuuggcg uccccgaugc ugggaugaag ccuagcugag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  3147
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt5)

<400>  3147
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

ugaugagacu guucccuugc uuucuccagc ugcuugccgg ccuggcucuc ccggccguuc      120

ccccucaaca gugggcgcug agcgcuggga acggauccuc ugaggucgaa guggugcccu      180

uccaggaggu cuggggccgg agcuacuguc gcgcccuuga aagacuggug gacguugugu      240

ccgaguaucc uucugaaguc gagcacaugu uuagccccuc cugcgugucu cuccugcggu      300

guaccgggug cuguggagau gagaaucugc auugcguucc uguggaaaca gccaacguca      360

cgaugcagcu ccugaagauc cgcagcggcg acagaccguc cuacguggag cuuaccuuca      420

gccaacacgu gcggugugaa ugccgccccc ugagagagaa aaugaagccu gagcggcgca      480

gacccaaagg gcggggaaag cgcagacggg aaaaacagcg cccuacagau ugucaucucu      540

gcggcgacgc uguccccaga cggugaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  3148
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt5)

<400>  3148
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

acagacagac agauacggcc cccagcccuu ccuaccaccu ucucccgggc cggcgcagaa      120

ccguggacgc ugccgcgucu cgggggcaag gacccgagcc ugcucccggc gggggagucg      180

aaggcguugg ggcccgcgga guggcccuga agcuguucgu gcagcugcuc ggcugcagca      240

gauuuggcgg ggcugucgug cgggccggag aggcugaacc uuccggcgcc gcgcgcucug      300

ccagcuccgg gagagaggaa ccccagccug aggagggaga agaggaagag gagaaagaag      360

aggaacgggg cccgcagugg cgccuggggg cuagaaagcc cggaucuugg acaggcgagg      420

ccgcuguuug ugccgauagc gcgccugccg cucgggcucc ccaagcccuu gcccgcgccu      480

ccggcagagg gggacgggug gcucgcagag gcgcggaaga gagcgggccu ccccauucuc      540

cgucccggag aggaagcgcc ucucgcgcug gcccugggcg ggccuccgag accaugaacu      600

uccugcucag cuggguccac uggucucugg cccugcuccu guaucuucau cacgcuaaau      660

ggucccaggc cgcgcccaug gcugaaggag gcggccagaa ucaucacgag gugguuaagu      720

uuauggacgu guaccagaga agcuauugcc acccuaucga aacacugguc gauauuuucc      780

aagaguaccc cgacgaaauc gaguauauuu uuaaacccuc cugugugccu cucaugcgcu      840

gcgggggaug uugcaacgau gagggccugg aaugugugcc gaccgaggaa ucuaauauca      900

caaugcagau uaugcggauc aagccccauc aggggcagca caucggagag augagcuucc      960

uucaacauaa caagugcgaa uguagaccua aaaaggaccg cgcccggcag gagaaaaagu     1020

ccgucagagg caaagggaag ggccagaagc gcaaacggaa gaaaagcaga uacaagucuu     1080

gguccguuua ugugggagcc cgcugcuguc ugaugcccug gagccucccu ggcccccacc     1140

cgugcgggcc uugcucugag cggagaaaac accuguuugu gcaagauccc cagaccugua     1200

agugcagcug uaaaaauacg gacucccggu gcaaggcucg ccagcuggaa cucaacgaga     1260

gaaccugucg gugcgauaag ccuagacgcu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3149
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt5)

<400>  3149
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugcucag cugggugcac uggucccugg cccuucugcu cuaccugcau cacgcuaagu      120

ggucucaggc cgcgcccaug gcugagggcg ggggacaaaa ucaucacgaa gucguuaaau      180

uuauggacgu guaucagaga agcuacugcc auccuaucga gacccuugug gauauuuucc      240

aggaauaucc ggacgagauc gaauacauuu uuaagcccuc cugugucccu cugaugcggu      300

gcggcgggug uugcaacgau gagggacucg agugugugcc cacagaagag ucuaauauca      360

cgaugcagau uaugcgcauc aaaccucacc aaggccagca caucggggaa augagcuucc      420

ugcagcauaa caagugcgag uguagaccca aaaaggaccg ggcccgccag gagaagaaau      480

ccguuagagg aaagggcaaa ggccaaaagc ggaaacgcaa gaagucuaga uauaaaagcu      540

gguccgugua cgucggggcc cggugcuguc ugaugccuug gagccucccg ggaccccacc      600

cuugcggccc cuguucugaa cgcagaaagc aucuguuugu gcaggauccu cagaccugca      660

aaugcuccug uaagaauaca gacagccggu gcaaagcucg ccagcuugag cugaacgaaa      720

gaaccugucg gugcgauaag ccccgcagau gaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  3150
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt5)

<400>  3150
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

cccugcucag acggcugcuu cuggccgcuc uccugcagcu ugccccugcg caagcuccgg      120

ugucccagcc cgacgccccu ggccaccagc gcaaggucgu uucuuggauc gauguguaca      180

ccagagccac augccagccc cgggaggugg ucgugccucu gacgguugaa cucaugggga      240

ccguggcuaa gcaacugguc cccagcugug ugacaguuca gcgcugcgga ggcuguugcc      300

cugacgaugg gcuggagugu gugccgaccg gacagcauca ggucagaaug caaauucuca      360

ugauccggua ucccuccucu cagcugggcg aaaugagccu ugaggaacac ucccagugcg      420

agugucgccc uaagaaaaag gacucugccg ugaaacccga uagagcugcc acaccucauc      480

accggcccca gccgcgcagc gugccugggu gggacuccgc gcccggagcc ccuagccccg      540

cugauauuac ccaucccacc ccugccccgg gccccucugc ucacgccgcg ccuuccacaa      600

cgagcgcccu gacccccggc ccugcugccg cugccgccga cgcugcggcc ucuuccgucg      660

cuaaaggggg agccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  3151
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt5)

<400>  3151
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcauc       60

ugcucggcuu cuuuagcgug gccugcuccc ugcuugcugc cgcgcugcuc cccgggccua      120

gagaggcucc ggccgccgcu gccgcuuucg aaucuggacu ggaccuuagc gaugccgagc      180

ccgacgcggg cgaagccacc gcuuacgccu ccaaggaucu ggaggaacag cuccggucug      240

ucagcuccgu ugacgagcug augacagugc uguauccuga guacuggaaa auguauaagu      300

gucaacuccg caaaggggga uggcagcaca acagagaaca ggcuaaucug aacucucgga      360

cggaggaaac caucaaguuu gccgcggccc acuacaauac agagauucuu aaaagcaucg      420

auaacgagug gcgcaagacc cagugcaugc ccagagaagu guguauugac gucggcaagg      480

aguucggggu ggcuacaaau accuuuuuca aaccucccug cguuuccgug uaucggugug      540

gaggcugcug uaacagcgaa ggccugcaau gcaugaauac aucuaccucc uaccucagca      600

agacgcuguu ugagaucacc gucccucuuu cucaggggcc gaaacccgug acaauuuccu      660

ucgccaacca uaccagcugu cgcugcaugu cuaagcugga uguuuauaga caggugcacu      720

ccaucauccg gcgcagccuc ccugcuacac ugccccagug ucaagccgcc aauaaaaccu      780

gcccuacgaa cuacaugugg aauaaccaua uuugcagaug ucuggcucag gaagacuuua      840

uguucuccuc ugaugcggga gacgauagca cagacggcuu ucacgauauc ugcgggccca      900

auaaggagcu cgacgaggaa accugucagu gcgucugucg ggccggacug cgcccggcuu      960

ccugcggccc ucacaaggag cuugacagaa acagcuguca gugcgugugu aaaaauaagc     1020

uguuccccuc ucaaugcggg gccaaccggg aauuugauga gaacacaugu cagugcgugu     1080

gcaaacgcac cuguccuaga aaucagcccc ucaaccccgg aaagugcgcc ugugaaugca     1140

ccgagucccc ucaaaaaugu cugcuuaagg gcaaaaaguu ccaucaccag acaugcagcu     1200

guuaccggag accgugcacg aaucgccaga aggcuuguga gcccggcuuc ucuuauagcg     1260

aagaggucug ccgguguguu ccuuccuacu ggaaaagacc ccagaugucu ugaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  3152
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt5)

<400>  3152
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguaca       60

gagagugggu ggucguuaac guguucauga ugcuguaugu gcagcucguc caaggcagcu      120

ccaaugaaca cgggcccgug aagcggucua gccaguccac ccuggagcgc ucugaacagc      180

agaucagagc cgcuagcucc cuugaggaac ugcuccggau uacacauucu gaggacugga      240

aacuguggcg cugcagacuu cggcucaaga gcuuuacguc cauggauagc cgcucugccu      300

cccacagaag cacccgguuc gcggcuacau uuuacgacau cgagacccug aaaguuauug      360

augaagagug gcaacgcaca caguguucuc cuagagaaac cugcguggag gucgccuccg      420

agcugggaaa gagcacaaac accuucuuua aaccgcccug ugugaauguu uuccggugcg      480

gcggguguug caacgaagag ucucugaucu guaugaauac guccaccagc uauauuucca      540

agcagcucuu ugaaaucucu gugccucuga caagcguccc cgagcuugug ccugugaagg      600

ucgccaacca uaccggaugc aaaugucugc ccacagcucc ucgccacccg uacuccauca      660

uuagacggag cauccagauu cccgaagagg accgcugcuc ucauuccaag aaacucuguc      720

cuaucgauau gcugugggac agcaauaagu gcaaaugcgu ucuucaagag gaaaaccccc      780

uggccggcac cgaggaucac ucucaccucc aggaaccugc ucuguguggg ccccauauga      840

uguucgacga ggauagaugc gaaugugugu gcaagacgcc guguccuaag gaccugauuc      900

agcaccccaa aaauugcagc uguuuugagu gcaaggaguc ccucgaaaca uguugccaga      960

aacauaagcu guuccacccu gauaccuguu cuugcgagga ccggugcccc uuucacacaa     1020

gacccugugc cagcggaaaa accgcgugcg ccaagcauug ucgcuucccu aaagaaaagc     1080

gggcugccca aggcccgcac uccagaaaga accccugagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  3153
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt6)

<400>  3153
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

cagacgaaac aggauuugaa cacucaggau uauggguauc aguauuagca ggauuacuac      120

ucggagcaug ccaagcacac ccaaucccag acucaucacc auuauuacaa uucggaggac      180

aagucagaca acgauacuua uacacagacg acgcacaaca aacagaagca cauuuagaaa      240

uaagagaaga cggaacagua ggcggagcag cagaucaauc accagaauca cuacuacaac      300

uaaaagcacu aaaaccagga guaauacaaa uauuaggagu aaaaacauca agauucuuau      360

gccaaagacc agacggagca cuauacggau cauuacacuu ugauccagaa gcaugcucuu      420

ucagagaacu acuacuagaa gacggauaca acguauacca aucagaagcu cauggacuac      480

cuuuacaccu accaggaaac aaaucaccac acagagaucc agcucccaga ggacccgcaa      540

gauuccuacc auuaccagga uuaccaccag cauuaccaga accaccagga auacuagcac      600

cacaaccacc agacguagga ucaucagacc cauuaucaau gguaggacca ucacaaggaa      660

gaucaccauc auacgcauca uaaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  3154
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt6)

<400>  3154
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

cauuuccacc acuauuauua cuacuauuuu ggggagucgu aucacauagc uuucccgcaa      120

cacuagaaac ccaagaacaa gacguagacu uaguacaaaa auaucuagaa aaauacuaua      180

accucaaaaa cgacggaaga caagucgaaa aaagaagaaa cagcggacca guuguagaaa      240

aacuaaaaca aaugcaagaa uuuuucggau uaaaaguuac uggaaaacca gacgcagaaa      300

cacuaaaagu aaugaaacaa ccaagaugcg gaguaccaga uguagcacag uucguauuaa      360

cagaaggaaa cccacguugg gaacaaacac aucuuacaua cagaauugaa aauuacacac      420

cugaccuacc aagagcagac guagaccacg caauagaaaa agccuuucaa uuauggucaa      480

acguaacacc auuaacauuc acaaaaguuu cugaagggca agcagacaua augaucucau      540

uuguuagagg agaccaccga gacaauagcc cauucgacgg gccaggagga aaccuagcac      600

augcuuucca accaggaccu ggaauaggag gcgacgcaca uuucgacgaa gacgaacgau      660

ggacaaacaa uuucagagaa uacaaccuac auagaguagc agcccacgaa uuaggccaca      720

gccuaggcuu aucacacuca acagacauug gagcucuaau guacccuucc uacacauuuu      780

caggagacgu acaauuagcc caagacgaua uagacggaau acaagcaaua uacggacgau      840

cacaaaaccc aguacaacca auaggaccac aaacaccaaa agcaugcgac ucaaaauuaa      900

cauuugacgc cauaacaaca auaagaggag aaguaauguu uuucaaagac cgauuuuaua      960

ugagaacaaa uccauucuac ccagaaguag aauuaaacuu uauaagugua uucuggccuc     1020

aauuaccaaa cggauuagaa gcagcauaug aauuugcaga cagagacgaa guacgauucu     1080

uuaaaggaaa uaaauacugg gccguacaag gacaaaacgu auuacaugga uacccaaaag     1140

acauauacag cucauucggg uuuccaagaa caguaaaaca cauagacgcc gcauuaucag     1200

aagaaaacac aggcaaaaca uauuuuuucg uagcaaacaa auacuggaga uacgacgaau     1260

acaaaagauc aauggaccca ggauauccaa aaaugauagc acacgauuuc ccuggcauug     1320

ggcacaaagu agaugcagua uucaugaaag auggcuuuuu cuacuucuuu cacggaacuc     1380

gacaauacaa auucgaccca aaaacaaaaa gaauacucac acuacaaaaa gcaaacaguu     1440

gguucaauug uagaaaaaac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  3155
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt6)

<400>  3155
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcauu       60

cauucccacc acuacuauua uuauuauucu ggggaguagu aucacauuca uuuguacuaa      120

cugaaggaaa uccuagaugg gaacaaacuc acuuaaccua uagaauagaa aacuauacac      180

cagaccuacc aagagccgac gucgaccacg caauugaaaa agcauuccaa uuauggagua      240

acguaacacc acuaacauuc acaaaaguau cagaaggaca agcagacaua augauaucau      300

uugucagagg agaccaccga gacaacucac cauuugacgg accuggagga aaucucgcac      360

acgcauucca accaggacca ggaauaggag gagacgcaca uuuugaugaa gaugaacgau      420

ggaccaacaa uuuuagagaa uacaaccuac accgaguagc cgcacacgaa cucggacaca      480

gccuaggacu aucacacuca accgacaucg gagcacuaau guacccauca uacacauucu      540

ccggagacgu ccaacuagcu caagacgaca uagacggaau acaagcaaua uacggaagau      600

cacaaaaucc uguacaacca auaggaccac aaaccccaaa agcaugcgac ucaaaauuaa      660

cauuugacgc aauaaccaca auuagaggug aaguaauguu uuucaaagau agauuuuaca      720

ugagaacaaa ucccuucuau ccagaaguag aauuaaauuu cauaucagua uucuggccac      780

aacuaccaaa uggauuagaa gcagcauacg aauuugcaga uagagacgaa guaagauucu      840

ucaaaggcaa caaauacugg gcaguacaag gccaaaacgu acuacacgga uauccuaaag      900

acauauacuc uuccuuugga uuuccuagaa caguaaaaca cauagaugcc gcacuaucag      960

aagaaaacac cggaaaaaca uacuucuucg ucgccaauaa auacuggaga uacgacgaau     1020

auaaacgauc aauggaccca gguuacccaa aaaugauagc acacgauuuc ccaggaauag     1080

gacacaaagu ugacgcaguc uuuaugaaag acggauuuuu cuacuucuuu cacggaacac     1140

gacaauacaa auucgauccc aaaacuaaaa gaauccuaac uuuacaaaaa gccaauucuu     1200

gguuuaauug uagaaaaaac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  3156
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt6)

<400>  3156
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

aaaacauacu caaaauucua auggacucau acucgaaaga aucaaaaaua caaacagucc      120

gcagaguuac aucagucucg uuacuagcag uauaccugac gaugaacaca uccucguuag      180

uacucgcuaa accuauagaa aauaccaacg auaccaguau aaaaaacgua gaaaaauuaa      240

gaaaugcacc aaacgaagaa aacaguaaaa aaguagaaga caguaaaaau gacaaaguag      300

aacauguaaa aaacauagaa gaagcaaaag uugaacaagu agcaccagag guaaaaucca      360

aaagcacauu aagaagcgcg ucaaucgcca acacaaauuc agagaaguac gacuucgaau      420

acuuaaacgg auuaaguuau acagaacuaa caaaucucau uaaaaauauc aaauggaacc      480

agauaaaugg acuauuuaau uacucaacag gaucacaaaa auuuuucgga gacaaaaaua      540

gaguacaagc aauuauaaac gcuuuacaag aaagcggacg aacguauaca gcaaacgaua      600

ugaaaggaau ugaaacauuc acagaaguac uacgcgcugg uuuuuaucug ggcuauuaua      660

acgacggacu aucauaccuc aacgaccgaa acuuccaaga uaaaugcaua ccagcgauga      720

uugcaauuca aaaaaaccca aacuuuaaac uaggaaccgc aguccaagau gaaguaauaa      780

cgucgcucgg aaaacuaaua ggaaaugcaa gcgcuaaugc agaaguugua aauaacugug      840

uucccguacu aaaacaauuc cgagaaaauu uaaaucaaua cgcaccagau uacgucaaag      900

gaacggccgu uaaugaacuu aucaaaggaa uagaauuuga uuucucagga gcagcuuaug      960

aaaaagacgu aaagacuaug ccaugguacg gaaaaauaga ucccuuuaua aaugagcuga     1020

aggcacuagg ccuuuacgga aacaucacau cagcuacaga augggcguca gaugucggga     1080

uauacuaucu aucaaaauuc ggacuuuacu caaccaaccg aaaugauaua guacaauccu     1140

uagaaaaagc aguagauaug uauaaauacg gaaaaauagc uuucgucgca auggaacgaa     1200

ucacauggga uuaugacggu auaggaagca auggaaaaaa aguagaucau gacaaauucc     1260

uagaugacgc agaaaaacau uaccucccca aaacauacac cuucgauaac ggcacauuca     1320

uaauaagagc uggagacaaa guaucagaag aaaaaaucaa acguuuauac ugggcaucac     1380

gagagguuaa aucacaauuc cauagaguag ucgguaauga caaagcauua gaaguaggca     1440

augcagacga cguacucaca augaaaauau ucaauucucc ugaagaauau aaauuuaaua     1500

ccaacauuaa cggaguaucu acagacaaug gaggccuuua cauagaacca agaggaacgu     1560

ucuauaccua cgaaagaaca ccacaacaau caaucuuuuc auuagaagaa cuauuuagac     1620

acgaauacac acacuaucug caagcacgau accuggugga uggacuaugg ggacaagggc     1680

cauuuuauga aaaaaaccgc uuaacauggu uugaugaagg cacagccgaa uuuuucgcag     1740

gaucaaccag aacaucgggu gucuuaccac ggaaaucaau acucggguac uuagcaaaag     1800

acaaaguaga ucauagauau ucauuaaaaa aaacacuaaa uaguggauau gaugacucgg     1860

auuggauguu uuacaacuau gguuuugcgg uagcacauua uuuauaugaa aaagauaugc     1920

ccacauucau aaaaaugaac aaagcuauau uaaauaccga uguaaagagc uaugaugaaa     1980

uaauaaaaaa acucagugau gaugcaaaua aaaacacuga auaucaaaac cacauacaag     2040

aacuagcaga caaauaccaa ggagcaggua uuccguuagu uucagaugau uacuuaaaag     2100

accacggaua uaaaaaagca ucagaaguau acagugaaau aucgaaagca gccagccuua     2160

caaacaccuc aguaacagca gagaaaaguc aauauuucaa cacauuuaca cuaagaggaa     2220

cauacacggg ggaaaccuca aaaggagaau uuaaagauug ggaugaaaug uccaaaaaac     2280

uagacggaac acuagagagc uuagcuaaaa acaguuggag cggauacaaa acuuuaacgg     2340

cauacuuuac uaacuaccga guuacaagug acaauaaggu ucaauacgac guaguauuuc     2400

acggaguacu aacagacaac gcugauauua guaacaacaa agcgccuauc gcuaaaguaa     2460

caggaccauc gacuggggca gucggaagga acauagaauu uucugggaaa gacaguaaag     2520

augaagacgg aaaaauaguu aguuacgauu gggauuuugg cgauggagcu accucucgug     2580

gaaagaacuc ugugcaugca uacaaaaaag caggaacaua uaacguaacc cuaaaaguaa     2640

cagacgacaa aggagcaaca gcuacagaga gcuuuaccau agaaauaaaa aacgaagaua     2700

caacgacacc aauaacaaaa gagauggaac cuaaugauga cauaaaagaa gcuaacggac     2760

ccauagugga aggaguaaca gugaaaggag accugaaugg cagcgaugac gcugauacuu     2820

uuuauuucga ugucaaagaa gacggugacg uaaccauuga acuaccguac agcggcaguu     2880

caaauuuuac augguuggua uauaaagaag gagacgacca aaaccacaua gcaucuggaa     2940

uagauaaaaa uaacucaaaa guugguacau uuaaaaguac aaaagguaga cacuauguau     3000

ucaucuauaa acacgacagc gcaucaaaca uauccuauuc ccucaauaua aagggacuag     3060

gaaaugaaaa acugaaagaa aaagaaaaua acgauuccag ugacaaagca acuguaaucc     3120

caaauuuuaa uacaacaaug caaggaucuu uauuaggaga cgauagucgc gacuauuacu     3180

cauuugaagu gaaagaagaa ggagaaguaa auauagaacu ugacaaaaaa gacgaguucg     3240

gaguaaccug gacucuccac ccagaaucaa auauaaacga uagaaucaca uacggacaag     3300

uagacgguaa caaagucuca aauaagguaa aacuuagacc agggaaauac uauuuacucg     3360

uauauaaaua cucuggcagc ggcaacuacg aguuacgggu uaacaaauaa ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  3157
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt6)

<400>  3157
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

gggucaccuu uauaagucua cuuuucuuau uuuccucagc auauagcaua gcaaauacaa      120

auuccgaaaa auaugacuuc gaauaccuaa acggucuuag uuacacagaa uuaacuaacc      180

uaauuaaaaa cauaaaaugg aaucaaauaa auggcuuauu uaauuauuca acagguaguc      240

aaaaauucuu cggagauaaa aacagagugc aagcaauaau aaacgcccua caagagucag      300

gacgaacaua uacagcaaau gacaugaaag gaauagagac auucacagag guauuacgug      360

ccggauucua ccuaggauac uacaacgacg guuuaucuua cuuaaaugac agaaacuucc      420

aggauaaaug uauaccagca augauagcaa uacagaaaaa cccuaauuuc aaacucggaa      480

cggcgguuca agacgaagua auuacaucuu uagguaaauu gauaggaaac gcaucagcga      540

acgccgaggu aguaaacaau ugcguaccgg uccuuaaaca auuuagagaa aaucuaaacc      600

aauaugcacc agacuacgug aaaggaacag cagugaauga auuaauaaaa ggcauugagu      660

ucgacuucuc aggagcagca uaugaaaaag auguaaaaac aaugccaugg uacggaaaaa      720

uagauccauu cauaaaugaa cuaaaagcau uaggauuaua cggcaacauc accagugcaa      780

cugaaugggc aucagauguc gggauauacu auuuaucaaa auucggacuc uauagcacaa      840

accgaaacga cauaguacaa ucacuagaga aagcaguaga cauguacaaa uacgggaaaa      900

uagcauuugu agccauggaa cgaauuacau gggacuacga uggcauaggu agcaauggaa      960

agaaaguaga ucacgauaaa uuccuugacg acgcagaaaa acacuaucuu ccuaaaacau     1020

acacuuuuga uaacgguacc uucauaauac gagccgguga uaaaguaagc gaagagaaaa     1080

uaaaaaggcu auauugggca agcagagaag ucaaaagcca auuucauaga guaguaggaa     1140

augacaaagc acuagaaguu ggaaacgcug acgauguucu aacaaugaaa aucuucaacu     1200

caccugaaga auacaaauuc aacacaaaca uaaauggagu aaguaccgac aacggaggau     1260

uauauauaga acccaggggg acguuuuaua ccuacgagag aaccccucaa caaucuauau     1320

uuuccuuaga agaauuauuu cgacaugaau acacacacua uuuacaagca cgauauuugg     1380

uagauggacu auggggacaa ggaccauuuu augagaaaaa cagacuuacg ugguucgacg     1440

aaggaacggc agaguucuuu gcaggaagua caagaacaag uggaguauua ccaagaaaau     1500

caauacuagg uuacuuagca aaagacaaag uagaucacag auacagccua aagaaaacac     1560

ugaauagcgg uuaugaugac agugauugga uguucuauaa uuacggauuc gcaguagcuc     1620

acuaucuaua ugaaaaagau augccaacau ucaucaaaau gaauaaagca auacuuaaca     1680

ccgacguuaa aucauaugac gaaauaauaa agaaauuaag ugacgacgca aacaaaaaua     1740

ccgaauacca aaaccacauc caagaacuag cagacaaaua ucaaggugca ggaauaccau     1800

uaguaucaga cgacuaccuc aaagaccaug gauacaagaa agcguccgaa guauacucag     1860

aaauaaguaa agcagcauca uugacuaaua cuucaguaac agcagaaaaa ucacaauacu     1920

uuaacacauu cacacuucgc ggaacauaua cgggagaaac cucaaaaggu gaauuuaaag     1980

auugggacga aaugaguaaa aagcucgacg gcacucuaga aucauuggcu aaaaacuccu     2040

ggucaggaua uaaaacacua acagccuacu ucaccaauua cagagucacc ucagauaaua     2100

aaguacaaua ugacguagua uuucauggag ucuuaacaga caacgcugau auaaguaaca     2160

auaaagcgcc uauagcgaaa guaacaggac caucaacggg agcaguagga agaaauauug     2220

aguucucagg aaaggauagc aaagacgaag acggaaaaau uguaucuuau gauugggauu     2280

ucggagaugg agcaaccuca agagggaaaa acagugugca ugccuacaag aaagcaggaa     2340

cuuauaaugu aacacuaaaa gugacagaug acaaaggagc gacagcaaca gagagcuuca     2400

cgauugaaau uaaaaacgaa gauacuacaa cacccauaac aaaagaaaug gaaccaaaug     2460

augacauaaa agaagcaaac ggaccgauag uggaaggcgu aacgguaaaa ggagacuuaa     2520

auggaaguga ugacgccgac acauuuuacu uugauguuaa agaagacggu gaugucacaa     2580

uagaauuacc cuacucuggu aguuccaacu ucacuugguu aguauacaaa gaaggagaug     2640

aucaaaauca uauagcaucc ggaauagaca aaaacaauag caaaguaggc acauuuaaau     2700

ccacaaaagg acgucauuau guuuucauuu acaaacacga uagugcaagu aacauaaguu     2760

auucucuaaa uauaaaagga cuagguaaug aaaaacuaaa agaaaaagaa aacaacgaua     2820

gcagugacaa agcuacuguu aucccaaacu ucaacaccac aaugcaaggc agcuuacucg     2880

gagacgauuc acgagauuau uacagcuucg aaguaaaaga agagggggaa guaaacauag     2940

aacuagauaa gaaagacgaa uuuggaguaa cauggacacu acacccggaa ucgaacauaa     3000

augacagaau cacauaugga caaguagacg gaaacaaagu aucaaauaaa gucaaacuaa     3060

gaccuggcaa auauuaccua uuaguguaua aauauucagg aucagguaau uacgaacuga     3120

gagucaauaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  3158
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt6)

<400>  3158
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

ggguaacuuu cauaagucuu cuuuuccuuu ucucuucagc auacucgaug aagaaaaaca      120

uacuaaaaau acucauggau uccuauagca aagaaaguaa aauacaaaca guacggagag      180

uuacaucagu aagucuauua gcaguauacc uaacaaugaa uacaagcucc uuaguauuag      240

caaagccaau cgaaaacaca aacgauacgu caauuaaaaa cguagaaaaa uuacgaaacg      300

caccuaauga agaaaacuca aagaaagucg aagacagcaa aaacgauaaa gucgagcacg      360

ugaaaaauau agaagaagca aaaguagaac aaguagcccc agaaguaaaa aguaaaucaa      420

cucuaagauc ugcuucacgc agacgacgua aacgaauagc caacacaaau ucagaaaaau      480

augauuucga auaccuaaac ggguuaucau acacagagcu aacgaaucua aucaaaaaca      540

uaaaauggaa ccaaauaaau ggccuauuua auuauagcac aggaucccaa aaauucuucg      600

gcgacaaaaa ucgaguacaa gcaauaauua augcacuaca ggaaucuggc agaacauaua      660

cugcuaauga caugaaagga auagaaacau uuacagaagu acucagagca ggauuuuauu      720

uagguuauua uaaugacggc uuaaguuacc uaaaugauag aaacuuucaa gauaaaugca      780

uaccugcaau gaucgcaaua cagaaaaacc caaacuuuaa acuagggaca gcgguacaag      840

acgaaguaau aaccagcuua ggaaaacuca ucggaaacgc uucugcaaac gcggaaguug      900

uaaacaacug cguaccagua cuaaaacaau uccgagaaaa ccuaaaucaa uacgcuccag      960

auuauguaaa aggaacggcu guaaacgaau uaauaaaagg uaucgaauuu gauuucagcg     1020

gcgcagccua ugaaaaggac gucaaaacga ugccauggua uggaaaaaua gacccauuca     1080

uaaaugaacu gaaagcacuc ggacuuuacg guaauauaac aagugcuaca gaaugggcau     1140

cagacguagg aauauauuau uuaucaaaau ucggauuaua cucaacaaau agaaaugaca     1200

uaguacaaag ucuagaaaaa gcggucgaca uguacaaaua uggcaaaaua gcauuuguag     1260

cuauggaacg cauaacaugg gacuaugaug gaauagguuc uaacgguaag aaaguugauc     1320

augauaaauu cuuagaugac gcagaaaaac acuacuuacc aaaaacauau acauucgaca     1380

acggcaccuu uauaauacgu gccggagaca aaguuaguga agagaaaauu aaacgacuau     1440

acugggcuuc gagagaagua aaaucucaau uucacagagu cgugggaaac gauaaagcac     1500

uagaaguugg aaacgcagau gauguccuca caaugaaaau cuuuaauucc ccggaagaau     1560

acaaauuuaa uacgaauauc aacggcgugu caacugauaa uggaggacug uauauagaac     1620

cacgaggaac auucuacacu uaugaaagaa ccccgcaaca aagcauuuuc ucccuagaag     1680

aacuauucag gcaugaauau acacauuacc uccaagccag auaccuaguu gauggacuau     1740

ggggacaagg accguuuuac gagaaaaauc gauuaaccug guuugaugaa ggaacggcag     1800

aguucuuugc aggaucaaca agaacaagcg gaguacuacc aagaaaaucc auacuagguu     1860

acuuagcaaa agauaaaguu gaccacagau auaguuuaaa gaaaacccuc aacagugguu     1920

acgaugauuc ggauuggaug uuuuacaacu acggauucgc aguugcgcac uacuuauacg     1980

aaaaagauau gccaacguuc auaaaaauga acaaagcaau acuaaauacu gaugucaaaa     2040

gcuacgauga aauaauaaag aaacuaagug acgacgccaa uaaaaauaca gaauaccaaa     2100

accauauaca agaacuagcu gacaaauacc aaggugcggg aauaccucua guaagugacg     2160

acuaucuaaa agaucaugga uauaagaaag caucagaagu uuacucugaa aucagcaaag     2220

ccgcaucauu aacaaacacc ucaguaacag cugaaaaauc acaauauuuc aacacauuca     2280

cacuaagggg uacauauaca ggcgaaacca guaaaggaga auuuaaagau ugggacgaaa     2340

ugagcaagaa auuagaugga acucuagaau cuuuagccaa aaacucuugg ucaggauaca     2400

aaacauuaac ggcauauuuc acgaacuaua gaguuacaag ugauaauaaa gugcaauaug     2460

acguaguauu ucacggaguc cucacagaua acgccgauau uucaaauaau aaagcuccga     2520

uagcuaaagu aaccggucca uccacaggag caguaggcag aaacauugag uucucuggua     2580

aagauaguaa agaugaagau ggaaaaauag ucucauacga cugggauuuc ggagauggag     2640

caacaucaag agggaaaaac ucaguacaug ccuauaagaa agcgggaacc uauaacguaa     2700

cccuaaaagu cacagaugac aagggagcaa cggcuacaga aaguuuuaca aucgaaauua     2760

aaaaugaaga cacaacaaca ccaauaacga aggaaaugga accaaacgac gacaucaaag     2820

aagcuaacgg accaauaguu gaaggaguaa caguuaaagg agauuuaaac ggaucagaug     2880

augcggacac uuuuuacuuc gaugucaaag aagauggaga cgucaccauu gaauuaccuu     2940

auucaggaag caguaacuuc accugguuag uauauaaaga aggagacgau caaaaccaca     3000

ucgcuagcgg cauagauaaa aauaauucaa agguuggaac cuuuaaguca acaaaaggaa     3060

gacacuaugu auuuaucuac aaacaugauu ccgccucaaa cauauccuau agccugaaua     3120

ucaaaggccu aggaaacgaa aaauuaaaag aaaaagaaaa uaacgacagc ucagauaaag     3180

caacaguaau uccuaacuuu aacacuacaa ugcaagguag ccuauugggu gacgauagua     3240

gagacuauua cagcuuugaa gucaaagaag aaggagaagu uaauauagaa cuagacaaga     3300

aagaugaguu uggaguaacc uggacauugc acccugaauc caauauaaau gacagaauua     3360

cuuauggcca agucgacgga aauaaagucu caaacaaagu gaaacuaaga ccggguaaau     3420

auuaccuuuu gguguacaaa uauaguggcu caggaaacua ugaauuaagg gucaacaaau     3480

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  3159
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt6)

<400>  3159
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uucucaaaau aauacugaac cguggcaaaa caaugaaaag aaaaugccua aguaaaagac      120

ucaugcuggc caucacaaug gcuacaauau ucaccgucaa cagcaccuua ccuauuuaug      180

cagccguaga caaaaauaac gcuacugccg ccguacaaaa ugaaagcaaa agauacacug      240

ucucguaucu uaaaacacua aauuacuacg accuaguaga uuuauuagua aaaacagaaa      300

uagaaaaccu accugaucuc uuucaauacu caucagaugc caaagaauuu uacggaaaca      360

aaacacgaau gucuuuuaua auggaugaaa uaggccgcag agcuccacaa uacaccgaaa      420

ucgaccacaa aggaauacca acauuagugg aagugguaag agcaggauuu uauuuaggcu      480

uccacaacaa agaacuaaac gaaauaaaua aaagauccuu caaggaaagg guaauacccu      540

caauauuagc aauacagaaa aaccccaauu ucaaacuagg aacagaagug caagacaaaa      600

ucgucagcgc aacgggacuu cuagccggua acgaaacugc uccaccagaa guaguaaaca      660

acuucacccc aauccuacaa gacuguauua aaaacauaga cagauaugca uuagacgauc      720

uaaagucaaa ggcuuuauuu aacgucuuag cugcaccuac uuacgacaua acagaauacc      780

ucagggcaac aaaagaaaaa ccggaaaaua caccuuggua cggaaaaaua gauggcuuca      840

uaaacgaacu aaagaaauua gccuuauacg gaaaaauuaa cgauaauaac ucuuggauaa      900

uagauaaugg uauuuaccac auagcuccgu uagggaaacu gcauaguaac aauaaaaucg      960

gaauagaaac auuaaccgaa gucaugaaag uauacccaua uuuaucaaug caacacuuac     1020

aauccgccga ccaaaucaaa agacacuacg acagcaaaga ugcagaagga aauaaaauac     1080

cauuagauaa auucaagaaa gaaggaaaag aaaaauacug cccaaaaacc uauacuuucg     1140

acgauggaaa aguaauaaua aaagcuggag caagagucga agaagaaaaa guaaaacgac     1200

ucuacugggc aucaaaagaa gucaacucac aauucuucag agucuauggc auagauaaac     1260

cgcuagaaga gggaaacccc gaugacaucc uaacaauggu aauauacaau ucaccagaag     1320

aguauaaacu aaauagcgua uuauacggau acgacacaaa uaacggcgga auguacaucg     1380

aaccugaagg aaccuucuuc accuaugagc gagaagccca agaaaguaca uacacccugg     1440

aagaacuauu cagacaugaa uacacacauu accuacaagg acgauacgcc gugccaggac     1500

aaugggggcg aacgaaauua uacgacaacg acagacucac augguaugaa gaagguggag     1560

cagaauuauu cgcaggcagu acccguacau cagguauccu accaagaaaa ucuaucguca     1620

guaacauaca caacacaacu aggaauaauc gauacaaauu aucagacaca guacauucca     1680

aauacggggc cuccuucgaa uuuuacaacu acgcgugcau guuuauggau uauauguaua     1740

acaaagauau ggguauucua aacaaauuaa acgaccuagc caagaauaau gacguggacg     1800

gauacgacaa cuauauuagg gaccuaucau caaauuaugc auuaaacgac aaauaccaag     1860

accacaugca agagaggaua gauaauuacg aaaaccuaac aguaccauuu gucgcagacg     1920

auuauuuagu gcgacaugca uacaaaaauc caaacgaaau cuacagugag auuucagagg     1980

uagcaaaacu caaggaugcg aaauccgaag ucaagaaaag ucaauacuuc aguacauuca     2040

cgcuaagagg aucauauaca ggaggagccu caaaaggaaa auuagaagac caaaaagcaa     2100

ugaauaaauu cauagacgau ucauuaaaga aacuagauac cuacaguugg aguggcuaua     2160

aaacacucac ugcauauuuc acaaauuaca aaguagacuc aucuaauagg guaaccuacg     2220

auguaguauu ccacggauac cucccaaaug aaggcgacag caaaaacucu cucccauacg     2280

gaaaaauaaa cgggacauac aaagguacug aaaaagagaa aaucaaauuc agcagcgaag     2340

gauccuucga cccagacgga aaaauuguua guuaugaaug ggacuucgga gauggaaaca     2400

aaaguaauga agaaaaccca gaacauuccu augacaaagu cgggacuuac accguaaaau     2460

uaaaaguuac agaugauaaa ggcgaaucca guguaucaac aacaacagcc gaaaucaaag     2520

acuuaagcga aaauaaacuu ccaguaauau auaugcacgu accaaaaucu ggagcacuua     2580

accaaaaagu aguauucuac gguaaaggua cauacgaucc agacggauca auagcugggu     2640

aucaauggga cuuuggagac gguucagauu ucucaucaga acaaaauccc ucccacguau     2700

acacaaagaa aggugaauac acagugacac uaagagucau ggauagcagc ggccaaaugu     2760

cagagaaaac aaugaaaauc aaaauaacug aucccguaua uccaauaggc acagaaaaag     2820

aaccaaacaa cagcaaagaa acagccagcg gaccaauagu accaggcaua cccgucagug     2880

gaacuauaga aaauacaucc gaccaagacu acuuuuacuu cgauguaaua accccuggag     2940

aaguaaaaau agacauaaac aaauuagguu augggggcgc aacaugggua guguacgaug     3000

aaaauaauaa cgcaguaagu uaugcuacag acgacggcca aaaucuaucc ggaaaauuca     3060

aagcagacaa accaggcaga uacuauauuc aucuauauau guuuaacggu agcuacaugc     3120

cuuacaggau caacauagaa ggaagcguag guagauaggg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  3160
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt6)

<400>  3160
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaac       60

guaaaugccu uucaaaacgu cuaauguugg caauuacuau ggcaacaaua uuuacaguua      120

auuccacacu accaauauau gcagcuguag acaaaaacaa ugccacagcc gcaguacaaa      180

augaauccaa aagguacacu gucaguuauc uaaaaacucu uaacuauuac gaccuaguug      240

accuauuagu aaaaacagaa auagaaaacc uaccagacuu auuccaauac ucaucugaug      300

cuaaagaauu uuacggaaau aaaacccgca ugaguuuuau cauggaugaa auaggaagac      360

gagcgccuca auauacugaa aucgaucaca aaggaauacc gacgcuagua gaaguuguaa      420

gagccgguuu uuacuuaggc uuucacaaca aagaacuaaa cgaaauaaau aaacgaucau      480

uuaaagagag aguaauaccc agcauccuug ccauacaaaa gaauccaaac uucaaauuag      540

gaacagaggu acaagacaaa auaguauccg ccacaggccu auuagcagga aaugagacag      600

cacccccuga gguagugaac aauuucacac caauauuaca agauugcauu aaaaauauag      660

auagauaugc ucuagaugau cuaaaaucaa aagcacuauu caacguacua gcagcaccca      720

cauacgauau aacagaauac uuacgagcga ccaaagaaaa accagaaaac acaccauggu      780

acggaaaaau agacggcuuu auaaaugagu uaaagaaauu agcauuauau gguaaaauaa      840

augauaauaa cagcuggauu auagacaacg ggauauauca uauagcaccc cuaggaaaac      900

uacacucaaa caauaaaaua ggaauagaaa cauuaaccga agucaugaaa guuuauccuu      960

acuuauccau gcaacacuua caaucagcag aucaaauaaa aagacauuau gauucaaaag     1020

acgcagaagg uaacaaaaua ccccuagaca aauuuaagaa agaaggaaaa gaaaaauauu     1080

gcccaaaaac auacacauuu gacgacggga aaguaaucau aaaagcagga gcgagagucg     1140

aagaagaaaa aguaaaaaga cucuacuggg caucuaaaga aguaaacucc caauucuuca     1200

ggguauaugg aauagacaaa ccauuagaag aaggaaaucc cgaugacauu uugacaaugg     1260

uaaucuauaa uaguccggaa gaauauaaac ugaacagugu cuuauacgga uaugauacca     1320

acaacggugg aauguauaua gaaccagagg gaaccuucuu caccuaugaa agggaagccc     1380

aagaaucaac auacacucuc gaggaacuau uuaggcacga auauacacac uauuuacaag     1440

gacgauacgc aguaccagga caauggggca ggacaaaacu uuacgauaac gacagacuaa     1500

cuugguauga agaagguggc gccgaacuau ucgccgguuc aacucgcaca agcggaauau     1560

ugccacgaaa aucaaucgua ucuaacauac acaacacaac aagaaauaac cguuacaaac     1620

uaucagauac aguucacucc aaauacggag caaguuuuga auuuuacaac uacgccugua     1680

uguuuaugga cuacauguau aauaaagaua ugggcauacu aaauaaacug aacgauuuag     1740

cuaaaaacaa ugacguagac ggcuacgaca acuacauaag agauuuaagu uccaacuaug     1800

cacuaaauga uaaauaucaa gaucacaugc aagaaagaau agauaacuau gaaaauuuaa     1860

caguaccuuu uguggcagac gauuaccuug uucgacacgc auauaaaaac cccaaugaga     1920

uauauucaga aauuucagaa guagcaaaau uaaaagaugc aaaaagcgaa guaaagaaaa     1980

gccaauacuu cuccacauuu acccuccgag gaucauacac cggcggagcc uccaaaggaa     2040

aacuagaaga ccaaaaagcu augaacaaau ucauagauga cucccuaaag aaauuagaca     2100

cauauucaug guccggauac aaaacccuaa cggcuuacuu cacaaauuac aaagucgacu     2160

ccucaaauag gguuacauac gacgucguau uucacggaua ucuccccaau gagggagaca     2220

guaaaaauuc ccuaccauac gggaaaauaa acggaacaua uaaagggaca gaaaaagaga     2280

aaauaaaauu cucgucugaa ggaucuuuug accccgacgg gaaaauugug ucauaugaau     2340

gggauuuugg agauggaaau aaaucaaaug aagaaaaccc agaacacagc uaugacaaag     2400

uaggcacaua caccguaaaa uuaaaaguaa cagacgacaa aggagaauca ucaguaucca     2460

ccaccacagc agaaauuaaa gaucuaucug aaaacaaacu cccaguaauc uauaugcacg     2520

uaccuaaaag uggcgcucuc aaucaaaaag uaguauuuua cggaaaagga acauaugacc     2580

cagacggaag cauagcaggg uaucaauggg auuucggaga uggaucugau uuuucuucag     2640

aacaaaaccc aucgcacgua uacaccaaga aaggagaaua uacaguaaca cuaagaguua     2700

uggauucauc uggacaaaug ucugagaaaa cuaugaaaau aaaaauaaca gacccaguuu     2760

auccaauagg cacagaaaaa gaaccaaaca acaguaaaga aacagcauca ggaccaaucg     2820

ucccgggcau accaguaagu ggaacaauag aaaauacaag cgaccaagau uacuucuacu     2880

ucgauguaau aacaccaggc gaaguuaaaa uugacauaaa caaacucgga uauggaggag     2940

caacaugggu aguauaugau gaaaacaaua augccguauc uuacgccaca gacgauggac     3000

aaaaccuaag uggaaaauuu aaagcugaua aacccggacg cuacuacaua caccuguaua     3060

uguuuaacgg uucauacaug ccauacagga uaaacauaga agggagugug ggaagauaag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  3161
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt6)

<400>  3161
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

ggguuacuuu uauaucauua cuauuccuau ucucaucagc auacagcgua cagaacgaau      120

caaaaagaua cacaguaagu uacuuaaaaa cguuaaacua cuacgaccua guagauuuau      180

uagucaaaac cgaaauugaa aauuuacccg accuuuucca auacucuucc gaugcaaaag      240

aauuuuacgg caauaaaaca cgaaugagcu ucauaaugga ugaaaucggu agacgagcuc      300

cccaauacac agaaauagac cacaaaggaa ucccuacauu aguugaagua guuagagcag      360

gauucuaccu agguuuucau aacaaggaau uaaaugaaau aaauaaacga ucauucaaag      420

aacgaguaau accaucaaua cuugcaauac agaaaaaccc aaacuuuaaa cuuggaacug      480

aaguucaaga caaaauagug ucagcaacag gacuccuagc uggcaaugaa acagcuccac      540

cagaaguagu aaacaacuuu acaccaauau uacaagauug cauuaaaaau auagaccgcu      600

acgcuuuaga ugaucuaaaa aguaaagcac uauuuaacgu acuggcagca ccuacuuacg      660

acauaaccga auaccuacga gcaacaaaag aaaaaccuga aaacaccccc ugguacggaa      720

aaauagacgg auuuaucaac gaacuaaaga aauuagcacu uuauggaaaa auuaacgaua      780

auaauuccug gaucaucgac aauggcauau accauauagc uccacuagga aaauuacacu      840

caaacaacaa aauaggaaua gaaacacuaa cggagguaau gaaaguauac ccauaucuau      900

caaugcaaca ccuacaauca gccgaucaaa uaaaaagaca uuaugacuca aaagaugcag      960

aaggcaacaa aauaccacua gacaaauuca agaaagaagg aaaagaaaaa uauuguccga     1020

aaacauacac cuuugaugau ggaaaaguaa uuauaaaagc uggagcaaga gucgaagaag     1080

aaaaaguuaa acgauuauau ugggcaucaa aagaaguaaa uagucaauuu uuccgcgucu     1140

auggaauaga uaaaccccuu gaggaaggaa auccagacga cauccuaaca augguaauau     1200

auaauucacc ugaagaauac aaauuaaauu caguacuaua uggauacgac acaaacaacg     1260

gaggaaugua cauagaacca gaagguacau ucuuuacaua ugagagagaa gcacaagaaa     1320

gcacauacac ucuagaagaa cuauucagac acgaguacac ccacuaccua caaggucgau     1380

augcuguacc aggacaaugg ggaaggacaa aacuauacga uaaugacaga cuaaccuggu     1440

acgaagaagg aggagccgaa cuauucgcag gaagcacacg uacaucaggu auacuaccaa     1500

gaaaauccau agucagcaac auacauaaca cgacacguaa caacagauac aaauuaagug     1560

acacaguuca uagcaaauau ggagcuucau uugaguuuua uaacuacgca uguauguuca     1620

uggauuacau guacaacaaa gacaugggaa ucuuaaauaa acuaaacgau uuagcuaaaa     1680

auaaugaugu agauggauac gacaacuaua uacgcgauuu aagcaguaac uacgcacuaa     1740

acgauaaaua ccaagaucac augcaagaaa ggauagacaa cuacgaaaau uuaacagucc     1800

cauucgucgc agacgauuac cuagucagac acgccuauaa aaauccuaac gaaauauacu     1860

cagagauuag cgaggucgca aaauuaaaag acgcaaaaag ugaaguaaag aaaagucaau     1920

auuucaguac auuuaccuua agaggcucau auacaggcgg agcaaguaaa ggaaaauuag     1980

aagaucaaaa agcaaugaau aaauucauug augacagccu aaagaaauua gacacauacu     2040

cauggucggg cuacaaaacc cuuaccgcuu acuuuacaaa cuauaaaguc gacaguucaa     2100

acagggucac auacgacguu guauuccacg gcuacuuacc aaaugaagga gacaguaaaa     2160

acucccuacc auacggaaaa auaaauggaa cguauaaagg aacagaaaaa gagaaaauaa     2220

aauucucauc agaaggauca uucgacccgg acggaaaaau uguuuccuac gaaugggacu     2280

ucggggacgg uaacaaaucg aacgaagaaa auccugaaca uucauaugau aaaguaggaa     2340

cauacacagu aaaacuaaaa gucacagaug acaaaggaga aucguccgua ucuaccacaa     2400

cagcggaaau aaaagauuua ucagaaaaua aacuacccgu uauuuacaug caugucccaa     2460

aaagcggagc auuaaaccaa aaaguaguau uuuacggaaa aggcacauau gauccagacg     2520

gaucaauugc cgguuaucaa ugggacuucg gagacggaag cgacuucagu agugaacaaa     2580

accccuccca uguauacaca aagaaaggug aauacacagu caccuuaaga guaauggacu     2640

caucaggaca gaugagugag aaaacaauga aaauaaaaau aaccgacccc gucuauccaa     2700

uaggaaccga aaaagaacca aauaauucaa aagaaacagc aucaggacca auaguacccg     2760

gcaucccagu aucuggcacc aucgaaaaca ccucugauca agacuacuuc uacuucgacg     2820

uaauaacacc aggugaagua aaaauugaua ucaauaaacu aggauacggc ggagcaacau     2880

ggguaguuua cgacgaaaac aacaacgcag uuagcuacgc uacagaugac ggacaaaacc     2940

uaagugggaa auuuaaagca gacaaaccug gaagauauua uauccaucuc uacauguuca     3000

acgguucuua uaugccauau agaauaaaca uagaaggcuc aguaggaaga uaaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3162
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt6)

<400>  3162
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

ggguuacauu caucagcuua cuauuccuau ucaguagcgc cuacagcaug aaaagaaaau      120

guuuauccaa aagacuaaug cuagcuauca caauggcuac aauuuucaca gugaacucua      180

cauuaccaau auacgcugca guugauaaaa acaacgcaac agccgcuaga agaagaagaa      240

aacgaguaca aaacgaaagc aaaagauaca ccgucucuua cuuaaaaaca cuaaauuacu      300

acgaucuggu agaccuucua guaaaaacug aaauagaaaa ucuaccagac uuauuccaau      360

auucaagcga cgcaaaagaa uuuuacggaa acaagacaag aaugaguuuu auuauggaug      420

aaauuggacg uagagcaccc caauacaccg aaauagauca caaaggcaua cccaccuuag      480

uggaaguugu aagagccggg uucuacuuag gauuucauaa uaaagaauua aaugaaauaa      540

auaaacgauc cuucaaagaa agagucauac caagcauucu cgcaauucag aaaaacccaa      600

auuucaaacu aggaaccgaa guacaagaua aaauuguauc agcaaccgga uuauuagcug      660

guaacgaaac agcucccccu gaaguaguaa auaacuuuac ccccauauua caagauugca      720

uuaaaaauau agacagauac gccuuagacg accuaaaauc aaaagcacua uucaaugucc      780

ucgcugcucc aacauaugac auaacagaau accuuagagc gacuaaggaa aaacccgaaa      840

acaccccaug guaugguaaa auagaugguu ucauaaacga acuaaagaaa cucgcacuau      900

acggaaaaau aaacgacaac aauagcugga uaauagacaa uggaauauau cauauagcac      960

cauuaggaaa acuacauuca aacaauaaaa ucggaauaga aacauuaaca gaaguaauga     1020

aaguauaucc cuauuuaagc augcaacauc uacagucugc ggaccaaaua aaacgucauu     1080

acgacucuaa agacgcagaa ggaaacaaaa uuccacuaga caaauuuaag aaagaaggga     1140

aagaaaaaua cugcccaaaa accuacacuu uugaugaugg aaaaguaauu auaaaagcug     1200

gagcacgcgu agaagaagaa aaaguaaaac gauuauacug ggccaguaaa gaagugaaua     1260

gucaauucuu cagagucuau ggaauugaca aaccucuaga agaaggcaac ccagacgaua     1320

uacuaaccau gguuauauau aauucuccag aagaauacaa acuaaauuca guauuauacg     1380

gauaugauac caacaacgga gggauguaca uagaaccuga agguacuuuc uuuacauacg     1440

aaagagaagc acaagaaagc acauauaccu uagaggaacu auuuagacac gaauauacac     1500

acuaccugca aggaagauau gcugugccag gacaaugggg acguacuaaa cuauacgaca     1560

acgauagacu aacaugguau gaagaaggag gagcagaacu cuuugcuggc uccaccagaa     1620

caaguggaau cuuaccaaga aaaaguauag uaucaaacau acauaacaca acaagaaaua     1680

acagauacaa acucagcgac acaguacacu caaaauacgg agcuagcuuc gaauuuuaua     1740

auuacgcaug cauguucaug gacuacaugu acaacaaaga uaugggaauc uuaaacaaac     1800

uaaaugaucu agcgaaaaau aaugauguug augguuacga caacuauauc cgugaucucu     1860

caucaaacua cgcacugaac gacaaauacc aagaucauau gcaagaacgu auagauaauu     1920

augaaaauuu aacuguaccc uucguagcag augauuacuu gguuaggcau gcauacaaaa     1980

auccuaauga aauauacuca gaaauaucug aaguagccaa acuaaaagau gcaaaaagug     2040

aaguuaagaa aagccaauau uuuuccacau uuacauuacg aggauccuau acuggagggg     2100

ccaguaaagg uaaacuagaa gaccaaaaag caaugaacaa auucaucgau gauucccuaa     2160

agaaauuaga uacauauagu uggucaggcu acaaaacacu aacagccuau uuuacaaauu     2220

acaaaguaga uucaagcaau agaguuacau acgacguagu auuccauggu uauuuaccaa     2280

augaaggcga caguaaaaau ucauuaccau acggaaaaau aaauggaaca uauaaaggaa     2340

cggaaaaaga gaaaauaaaa uucuccucug aaggauccuu ugacccagac ggaaaaaucg     2400

uuagcuacga augggacuuc ggugauggua acaaaucaaa cgaagaaaac ccugaacaca     2460

gcuacgacaa aguaggaacc uacacaguca aacucaaagu aacagaugau aaaggugaau     2520

cuucuguuuc uacgacaaca gcagaaauca aagauuuauc cgaaaacaaa cucccaguca     2580

uauauaugca cguaccaaaa ucaggugcac uuaaucaaaa gguuguauuu uauggaaaag     2640

guacauauga ucccgacgga ucaaucgcag gauaccaaug ggacuucgga gacgggucag     2700

auuucuccuc ugaacaaaac ccaagccacg uauacaccaa gaaaggagaa uauaccguaa     2760

ccuuacgagu cauggauagu ucaggucaaa ugucagagaa aacaaugaaa aucaaaauaa     2820

cugauccagu auacccaauc ggaacagaaa aagaaccaaa uaauagcaaa gaaacagcaa     2880

guggacccau cgugccaggc aucccaguau cgggcacaau agaaaauacg agcgaccaag     2940

acuauuucua cuuugacguc auaacaccag gagaaguaaa aaucgauaua aauaaacuag     3000

gauacggagg agccacaugg gucgucuacg augaaaacaa caaugccgug agcuaugcaa     3060

cagacgaugg acagaaucuu ucugggaaau ucaaagcaga uaaaccagga cgauacuaua     3120

uacacuuaua cauguuuaau gguaguuaca ugccauaccg aauaaacauu gaaggaagcg     3180

uuggaagaug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  3163
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt6)

<400>  3163
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggua       60

ccuggauauu auucgcaugc cuacuaggcg cagcauucgc caugccauua ccaccacacc      120

caggacaccc aggauacauc aacuucucau acgaaguacu aacaccacua aaaugguacc      180

aaucaauaag accaccauac ccaucauacg gauacgaacc aaugggugga uggcuacacc      240

accaaauaau accaguacua ucacaacaac acccaccaac acacacacua caaccacacc      300

aucacauacc aguaguacca gcacaacaac caguaauacc acaacaacca augaugccag      360

uaccaggaca acacuccaug acaccaauac aacaucacca accaaaccua ccacccccag      420

cacaacaacc auaccaacca caaccaguac aaccacaacc acaccaacca augcaaccac      480

aaccaccagu acaccccaug caaccacucc caccacaacc accacuacca ccaauguucc      540

caaugcaacc cuuaccacca augcuaccag accuaacacu agaagcaugg cccucaacag      600

acaaaacaaa aagagaagaa gucgacuaag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  3164
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt6)

<400>  3164
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaucaaua agaccaccau acccaucaua cggauacgaa ccaaugggag      180

gaugguaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  3165
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt6)

<400>  3165
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaucaaua agaccaccac caaugcuacc agaccuaaca cuagaagcau      180

ggccaucaac agacaaaaca aaaagagaag aaguagacua aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  3166
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt6)

<400>  3166
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacacua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc auacccauca uacggauacg      240

aaccaauggg aggaugguaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  3167
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt6)

<400>  3167
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacauua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc accaaugcua ccagaccuaa      240

cacuagaagc auggccauca acagacaaaa caaaaagaga agaaguagac uaaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  3168
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt6)

<400>  3168
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu auucgcaugc uuaguaggag cagcauucgc caugccacua ccaccacacc      120

ccggccaccc aggauacaua aacuucucau acgaaguauu aacaccacua aaaugguacc      180

aaucaaugau acgcccacca uacuccucau acggauacga accaaugggc ggcugguuac      240

accaucaaau aauaccagua guaucccaac aacacccacu aacacacaca cuacaaucac      300

accaccacau accaguagua ccagcacaac aaccacgagu acgccaacaa gcacuaaugc      360

caguaccagg acaacaauca augacaccaa cacaacacca ccaaccaaac cuaccauuac      420

cagcacaaca accauuccaa ccacaaccag uacaacccca accacaccaa ccaaugcaac      480

cacaaccacc aguacaacca augcaaccac uccuacccca accaccacua ccaccaaugu      540

ucccacuaag accacuacca ccaauacuac cagaccuaca ccuagaagca uggccagcaa      600

cagacaaaac aaaacaagaa gaaguagacu aaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  3169
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt6)

<400>  3169
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaucaaug auaagaccac cauacucauc auacggauac gaaccaaugg      180

gaggauggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3170
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt6)

<400>  3170
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua uuaacaccac      120

uaaaauggua ccaaucaaug auaagaccac caccaauacu accagaccua caccuagaag      180

cauggccagc aacagacaaa acaaaacaag aagaaguaga cuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3171
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt6)

<400>  3171
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacauua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cauccaggac acccaggaua uauaaauuuc ucauacgaag      180

uauuaacacc acuaaaaugg uaucaaucaa ugauaagacc accauacagc ucauacggau      240

acgaaccaau gggaggaugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3172
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt6)

<400>  3172
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacacua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaucaaucaa ugauaagacc accaccaaua cuaccagacc      240

uacaccuaga agcauggcca gcaacagaca aaacaaaaca agaagaagua gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3173
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt6)

<400>  3173
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

ccuggauauu auucgcaugc cuacuaggag ccgcauucuc caugccacua ccaccacacc      120

caggacaccc aggauacaua aacuucucau acgaaguauu aaccccauua aaaugguauc      180

aaaacaugau aagacaccca uacacaucau acggauacga accaauggga ggauggcuac      240

accaccaaau aauaccagua guaucccaac aaacaccaca aucacacgca cuacaaccac      300

accaccauau accaauggua ccagcacaac aaccaggaau accacaacaa ccaaugaugc      360

cacuaccagg acaacacuca augacaccaa cacaacacca ccaaccaaac cuaccacuac      420

cagcccaaca accauuccaa ccacaaccag uacaaccaca accacaccaa ccacuacaac      480

cccaaucccc aaugcaccca auacaaccac uacuaccaca accaccacua cccccaaugu      540

ucucaaugca aucacuacua ccagaccuac cacuagaagc auggccagcc acagacaaaa      600

caaaaagaga agaaguagac uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3174
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt6)

<400>  3174
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaaauaug auaagacacc cauacacauc auacggauac gaaccaaugg      180

gaggauggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3175
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt6)

<400>  3175
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaaacaug auaagacacc caucacuacu accagaccua ccacuagaag      180

cauggccagc aacagacaaa acaaaaagag aagaaguaga cuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3176
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt6)

<400>  3176
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacauua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cauccaggac acccaggaua uauaaauuuc ucauacgaag      180

uauuaacacc acuaaaaugg uaucaaaaua ugauaagaca uccauauaca ucauacggau      240

acgaaccaau gggaggaugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3177
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt6)

<400>  3177
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacacua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaaaca ugauaagaca cccaucacua cuaccagacc      240

uaccacuaga agcauggcca gcaacagaca aaacaaaaag agaagaagua gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3178
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt6)

<400>  3178
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu auucgcaugc cuacucggug cagcauucuc aaugccacua ccaccacacc      120

caggacaccc aggauacaua aacuucucau acauacgaca cccauacaca ucauacggau      180

acgaaccaau gggaggaugg cuacaccacc aaauaauacc cguaguaucu caacaaacac      240

cacaaucaca cgcacuacaa ccacaccacc acauaccaau gguaccagca caacaaccag      300

gaauaccaca acaaccaaug augccauuac caggacaaca cucaaugaca ccaacacaac      360

accaccaacc aaaccuacca cuaccagcac aacaaccuuu ccaaccacaa ccaguacaac      420

cacaaccaca ccaaccacua caaccacaau caccaaugca cccaauacaa ccauuacuac      480

cacaaccacc acuaccacca auguucucaa ugcaaucacu acuaccagac cuaccacuag      540

aagcauggcc agcaacagac aaaaccaaaa gagaagaagu agacuaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  3179
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt6)

<400>  3179
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauauu cuucgccugc cuacuaggcg caucacuagc aaugccacua ccaccacacc      120

caggacaccc aggauauaua aacuucucau acgaaguacu aacaccucua aaaugguacc      180

aaaacaugau aagacaucca uacacaucau acggauacga accaaugggc ggaugguuac      240

accaccaaau aauaccagua gucucccaac aaacaccaca aucacacgca uuacaacccc      300

accaccacau acccauggua ccagcccaac aaccaggaau accacaacaa ccaaugaugc      360

cacuaccagg acaacacuca augacaccaa cacaacacca ccaaccaaac cucccauuac      420

cagcacaaca acccuuccaa ccacaacccg uacaaccaca accacaccaa ccacuacaac      480

cacaaucacc aaugcaccca auacaaccac uacuacccca accaccacua ccaccaaugu      540

ucucaaugca aucacuacua cccgaccuac cauuagaagc auggccagca acagacaaaa      600

caaaaagaga agaaguagac uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3180
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt6)

<400>  3180
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu auucgcaugc cuacuaggag cagcauucuc aaugccacua ccaccacacc      120

caggacaccc aggauacaua aacuucucau acgaaguacu aacaccacua aaaugguauc      180

aaaacaugau aagacaccca ucacuauuac cagaccuacc acuagaagca uggccagcaa      240

cagacaaaac aaaaagagaa gaaguagauu aaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  3181
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt6)

<400>  3181
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu auucgcaugc cuacuaggag ccgcauucuc aaugccccua ccaccacacc      120

caggacaccc aggcuacaua aacuucucau acgaagaccu auaccuagaa gcaauaagaa      180

uagacagaac agcauucguc cuaacaccau uaaaauggua ccaaaacaug auaagacacc      240

cauacacauc auacggauac gaaccaaugg gaggcuggcu acaccaccaa auaauacccg      300

uaguauccca acaaacacca caaucacacg cacuccaacc acaccaucac auaccuaugg      360

uaccagcaca acaacccgga auaccacaac aaccaaugau gccacuacca ggacaacacu      420

caaugacacc uacacaacac caccaaccaa accuaccauu accagcacaa caaccauucc      480

aaccacaacc aguacaacca caaccacacc aaccccuaca accacaauca ccaaugcacc      540

caauacaacc acuacuccca caaccacccc uaccacccau guucucaaug caaucuuuac      600

uaccagauuu accauuagaa gcauggccag caacagacaa aacaaaaaga gaagaaguag      660

auuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  3182
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt6)

<400>  3182
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

cauggauacu auucgcaugc cuacuaggag cagcauucuc caugccacua ccaccacacc      120

caggacaccc aggauacaua aacuucucau acgaaguacu caccccacua aaaugguacc      180

aaaacaugau aagacaccca acaccacaau cccacgcacu ccaaccacac caccacauac      240

caaugguacc agcacaacaa ccaggaauac cacaacaacc aaugaugcca cuaccaggac      300

aacacucaau gacaccaaca caacaccacc aacccaaccu accacuacca gcacaacaac      360

cauuucaacc acaaccagua caaccacaac cacaccaacc acuacaacca caaucaccaa      420

ugcacccaau acaaccacua cucccacaac caccacuacc cccaauguuc ucaaugcaau      480

cacuauuacc agaccuacca cuagaagcau ggccagcaac agacaaaaca aaacgagaag      540

aaguagacua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  3183
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt6)

<400>  3183
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuuuuc auacgaagua cuaaccccac      120

uaaaauggua ccaaaacaug auaagacacc ccuacacauc auacggcuac gaaccaaugg      180

gaggauggcu acaccaccaa auaauaccag uaguaucaca acaaacacca caaucacacg      240

cacuccaacc acaccaccac auaccaaugg uaccagcaca acaacccgga auaccacaac      300

aaccaaugau gccacuccca ggacaacacu caaugacacc aacacaacac caccaaccaa      360

accuaccacu accagcccaa caaccauucc aaccacaacc aguacaacca caaccacacc      420

aaccacuaca accacaauca ccaaugcacc caauacaacc acuacuacca caacccccac      480

uacccccaau guucucaaug caaucacuac uaccagaccu accacuagaa gcauggccag      540

caaccgacaa aacaaaaaga gaagaagucg acuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  3184
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt6)

<400>  3184
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

ggguagcuag acuaccucua cucuuaggac uccuauuguu accacggcca ggaagaccgu      120

uagaucuagc ggacuacaca uaugaucucg cagaagaaga cgacagugaa ccgcuaaauu      180

acaaagaucc auguaaagcg gccgcauuuu ugggagauau agcauuagau gaagaagacu      240

uaagagcauu ucaaguacaa caagcuguug aucuaagaag acacacggcc cgaaaaagca      300

guauaaaagc agcgguacca ggcaacacaa gcacgccauc augccaaagu acaaacggac      360

aaccacaaag aggggcuugc gggagaugga gaggaagaag cagaagcaga cgcgcagcua      420

cuucaagacc ugaaagaguu uggccugacg gcguaauacc auucguaaua ggaggcaauu      480

uuacaggaag ucagcgcgca guuuuucggc aagcaaugcg ccacugggaa aaacauacuu      540

guguaacauu cuuagagcga acagaugaag auuccuauau aguuuucaca uacaggcccu      600

gcggauguug uucauaugua ggaagacgcg ggggaggacc acaagcgaua aguauaggaa      660

aaaauuguga caaauucgga auaguugucc augaauuagg ucacguugug ggauucuggc      720

acgaacacac acgaccagau agagacagac auguaaguau aguaagggaa aauauacaac      780

cagggcagga auacaacuuu uuaaaaaugg aaccccaaga gguagaauca cuuggcgaaa      840

cuuacgauuu cgauaguaua augcauuaug cuagaaauac auuuucgaga ggaauauucc      900

uagacacuau aguaccgaaa uacgaaguaa auggagugaa acccccaaua ggccaaagaa      960

cuagacuauc aaaaggagac auagcacagg caagaaaauu auauaaaugu cccgcgugug     1020

gugaaacauu acaagauucu acaggaaauu uuucaucucc ugaauauccu aauggcuaua     1080

gugcacacau gcauugugua uggcgcauuu caguaacacc aggagaaaaa auuauuuuga     1140

auuucacaag ucuagacuua uacagaagua gauuauguug guaugacuau guagaaguca     1200

gggauggauu cuggagaaaa gcuccucuaa ggggaagauu uuguggaagc aaauuaccug     1260

aaccaauagu uagcacagau ucaagacuuu ggguagaauu uagaaguagu ucaaauuggg     1320

uaggaaaagg auuuuucgca guguaugaag caauuugcgg uggagaugua aaaaaagacu     1380

augggcacau acaaagccca aacuauccug augauuauag accaucaaaa guauguauau     1440

ggcgaauaca aguuagugaa ggguuucacg uaggauuaac uuuucaaucc uucgaaauag     1500

aaagacauga cucuugcgca uaugauuauu uagaaguuag agacggacau agugagagua     1560

guacucuaau cggaagauac ugcggcuaug aaaaaccuga ugacauuaaa agcacuagcu     1620

cuagauuaug gcuaaaauuu guaagugaug guagcauaaa uaaggcaggu uuugcaguaa     1680

acuuuuuuaa agagguugau gaauguucga ggccuaauag aggugguugu gaacaacggu     1740

gcuugaauac acuaggaagc uacaaaugcu caugcgaucc aggcuacgaa uuagcgccag     1800

auaaaagaag augugaagca gcauguggag gauuuuugac uaaacuaaau ggaucaauaa     1860

caaguccagg uuggccgaaa gaauacccuc cuaauaaaaa cuguauuugg caacuuguag     1920

caccuacuca auauagaaua ucauugcaau ucgauuuuuu cgagacagaa ggaaacgacg     1980

uauguaaaua ugacuuugug gaaguaagaa guggucuaac cgcugauagu aagcuacacg     2040

gaaaauucug cgguagugag aaaccagaag uaauaacguc acaauacaau aauaugagag     2100

uugaauuuaa gagugacaau acaguuucaa aaaaaggauu uaaagcacau uuuuucucag     2160

acaaagauga guguaguaaa gauaauggag gaugccagca agacugcgua aauacauucg     2220

gaagcuauga augucaaugu cgauccggcu uuguauuaca cgauaauaaa cacgauugua     2280

aagaagcugg augcgaucac aaaguaacga guacuagcgg aacaauuaca agcccaaauu     2340

ggccggacaa auaucccuca aaaaaagaau guacuugggc aauaucuucu acaccggguc     2400

auagagugaa auuaacauuc auggaaaugg acauagaauc acaaccagaa ugugcauaug     2460

aucaccuuga aguauucgau gguagagaug cuaaagcucc aguacugggu cgcuuuugug     2520

gaaguaaaaa acccgagccu guauuagcaa caggaucaag aauguuccuu agauucuacu     2580

ccgacaauuc aguacagaga aaagguuucc aagcuucuca cgcaacagaa uguggaggcc     2640

aagugcgagc ggauguaaaa acaaaagacu uauauucuca cgcacaguuu ggagacaaua     2700

auuauccagg agguguggau ugugaauggg uuauagucgc agaagaagga uacggaguag     2760

agcuagucuu ucaaacauuu gagguagaag aagaaacuga uuguggauac gacuauaugg     2820

aacucuuuga uggauacgac ucaacagcac cccgauuagg uagauauugu ggaucuggac     2880

cacccgaaga aguauauucc gcaggagaca gcguauuagu caaguuccac uccgaugaua     2940

ccaucacuaa aaaaggauuu caucuuagau auacaagcac aaaauuucaa gacacucuuc     3000

acagccgaaa auagggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  3185
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt6)

<400>  3185
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguag       60

cugguacuag augccuacua gcauuacucu uaccacaagu auuacuagga ggagcagcag      120

gauuaguccc agaacuaggu agaagaaaau ucgcagcugc cucaucagga agacccagcu      180

cacaaccuuc agacgaaguc cuaucagaau uugaauugag auuacuauca auguucggac      240

uuaaacaaag accaacacca ucaagagaug caguaguacc accauauaug cuagauuuau      300

auagaagaca cucaggacaa ccaggaaguc cagcuccaga ccauagauua gaaagagcag      360

caaguagagc aaacacaguc aggagcuuuc aucacgaaga aucacuagaa gaauuaccag      420

aaacaucagg aaaaaccaca agaagauuuu ucuuuaaccu uaguucaaua ccaacagaag      480

aauucaucac aagugcagaa cuacaagucu ucagggaaca aaugcaggac gcacuaggaa      540

auaauucauc auuccaucau agaauaaaua ucuaugaaau aauaaaacca gcaacagcca      600

acucaaaauu cccaguaaca agacuacuag acacaagacu aguaaaccaa aacgcaagca      660

gaugggaaag cuuugaugua acaccagcag uaaugcgaug gacagcacaa ggucacgcaa      720

aucacggauu cguagucgaa gucgcgcauc uagaagaaaa acaaggugua agcaaacgac      780

auguaagaau aaguagaagu uuacaccaag augaacauuc auggucacaa auaagaccac      840

uccuaguaac auucggacau gacgguaaag gacacccacu acacaaacga gaaaaaagac      900

aagcaaaaca uaaacaaaga aaaagacuaa aaucaucaug caaaagacau ccguuauaug      960

uugacuuuuc agauguagga uggaacgacu ggaucguagc acccccagga uaucacgcau     1020

ucuauuguca uggagaaugu ccauuuccau uagcagauca cuuaaauagc acaaaccacg     1080

ccauuguaca aacucuaguc aauucaguca auucaaaaau cccaaaagca ugcugcguac     1140

cuacagaacu aucagcaauu ucaaugcuau accuagacga aaaugaaaaa guaguacuua     1200

aaaacuauca agacaugguu guagaaggau guggaugcag auaaggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  3186
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt6)

<400>  3186
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauac       60

ccggaaacag aaugcuaaug guaguauuac uaugccaagu auuacuagga ggagcuagcc      120

augccagcuu aauuccugaa acaggcaaaa agaaaguagc agaaauacaa ggacacgcag      180

gaggaagaag aucaggacaa agccaugaac uacuaagaga cuucgaagca acauuacuac      240

aaauguuugg acuacgacga agaccacaac cuaguaaaag cgcagucaua ccagacuaua      300

ugagagaucu auaucgcuua caaagcggag aagaagaaga agaacaaaua cauucaacag      360

gauuagaaua cccagaaaga cccgcaucaa gagcaaauac agugagguca uuccaucaug      420

aagaacaucu agaaaauaua ccaggaacau cagaaaauuc agcauucaga uuuuuauuca      480

auuuaaguuc uauaccagaa aacgaaguaa uaucaucugc agaacuaaga uuauucagag      540

aacaaguuga ucaaggacca gacugggaaa gagguuuuca cagaauaaau aucuaugaag      600

uaaugaaacc uccagcagaa guaguuccag ggcaucuaau cacaagauua cucgauacaa      660

gauuaguaca ccauaacgua acacgauggg aaacauuuga uguaucacca gcaguucuaa      720

gauggacaag agaaaaacaa ccgaauuacg gauuagcaau agaaguuacu cacuuacauc      780

aaacaagaac ccaccaagga caacauguaa gaauaucccg aucauuacca caaggcucag      840

gaaauugggc acaacuaaga ccacuccucg uaacauuugg acaugacgga agaggacaug      900

cucucaccag aagaagacga gcaaaaagau caccaaaaca ccauagccaa agagcuagaa      960

agaaaaauaa aaauugcaga agacauaguu uauacguuga cuucucagau guaggaugga     1020

augauuggau aguagcacca ccugguuacc aagcauuuua uugucacgga gacuguccau     1080

uuccuuuagc agaucacuua aacaguacaa aucacgcaau aguacaaacu cuaguuaacu     1140

caguaaacag cucuauacca aaagcaugcu gugucccaac agaacuaucg gcaauuucaa     1200

uguuauauuu agaugaauau gauaaaguag uacuuaaaaa uuaucaagaa augguaguag     1260

aaggaugcgg auguagauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  3187
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt6)

<400>  3187
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

gauuaggucg uagagcacaa ugguuaugcu gguggugggg uuuacuaugu ucauguugug      120

gcccaccacc ccuaagacca ccauuacccg cagcagcggc ugcagccgca ggaggacaac      180

uauuaggaga uggaggaagu ccaggcagaa cagaacaacc accgccaagc ccccaaagcu      240

caucuggauu ucuauacaga agauuaaaaa cacaagaaaa gagagaaaug caaaaagaaa      300

uacuaucggu auuaggacug ccacaucgac ccagaccacu acacggauua caacaacccc      360

aaccacccgc acuucgacaa caagaagaac aacaacaaca acaacaacua ccaagaggcg      420

aaccuccacc aggaagauua aaaucagcac cacuauuuau guuagauuua uauaacgcau      480

uaucagcaga caaugacgaa gacggagcau cagaaggaga aagacaacaa ucauggcccc      540

augaagcagc aucaaguuca caacgaagac aaccaccucc aggagcugcu cauccauuaa      600

acagaaaauc acuucucgcc ccaggaagug gcucuggagg ugcaagucca uuaacaucag      660

cacaagauag cgcuuucuua aaugaugcag auaugguaau gucauuugua aaucuagucg      720

aauacgauaa agaauuuuca ccaagacaac gacaucauaa agaauuuaaa uucaauuuaa      780

gucaaauacc ugaaggugaa guaguuacag cugcugaauu ucgaauauau aaagacugug      840

uaaugggauc auuuaaaaac caaacauucu uaauaucaau auaucaaguu uuacaagaac      900

aucaacauag agauagugau cucuuuuuac uagauacaag aguaguaugg gcuagugaag      960

aagguugguu agaauuugac auaacagcua cgaguaauuu auggguugua acaccacaac     1020

auaauauggg ucuacaacuu agcguaguua cacgagaugg uguacaugua cacccaagag     1080

cagcaggucu aguaggaagg gauggaccuu augacaagca accauucaug guagcauucu     1140

uuaaaguaag cgaaguucau guaagaacua caagaucagc uucaucaaga agaagacaac     1200

aaagucgaaa cagaaguaca caaagucaag auguugcaag aguauccagu gcaucugauu     1260

auaacaguag cgaacuaaaa accgcaugua gaaaacacga auuauacguc agcuuucaag     1320

aucuaggaug gcaagauugg auaaucgcac caaaaggaua ugcagccaau uauugugaug     1380

gagaaugcag uuuuccuuua aaugcacaca ugaaugcaac aaaucacgcu auaguucaaa     1440

cacuuguuca cuuaaugaau ccugaauacg uaccaaaacc auguugcgca ccuacaaaau     1500

uaaacgcaau aucaguacua uacuuugaug auaauucaaa cguaauacuu aaaaaguaua     1560

gaaauauggu aguaagagca ugugguuguc acuaaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  3188
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt6)

<400>  3188
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaug       60

uaagaucacu ccgagcagca gcaccacacu cauuuguagc auuaugggca ccacuauucu      120

uauuaagauc cgcacucgca gacuucaguu uagacaauga aguacacuca ucauuuauac      180

aucgaagauu acgaucccaa gaaaggagag aaaugcaaag agaaauacuc ucaauacuag      240

guuuacccca cagaccaaga ccacaccuac aaggaaaaca uaauuccgca ccaauguuca      300

ugcuagaucu auacaacgca auggcaguag aagaaggagg aggaccagga ggccaagguu      360

ucucauaccc auauaaagca guauucagua cacaaggacc uccacuagca ucccuacaag      420

auucucacuu cuuaacugau gcagauaugg ucaugucauu cguuaacuua guagaacaug      480

auaaagaauu uuuucaccca agauaucacc aucgugaauu uagauucgac cuaucaaaaa      540

uuccagaagg agaagccgua acagcagcag aauucaggau uuauaaagac uauauccgag      600

aacgauucga caacgaaaca uucagaauau caguauauca agucuuacaa gaacaucucg      660

gccgagaauc agacuuauuc uuauuagauu cgagaacucu augggcaucu gaagaaggau      720

gguuaguauu ugauauaaca gcaacaagca aucauugggu aguaaacccc cgacauaauc      780

uaggauuaca auuaucagua gaaacacuug auggccaaag cauuaaccca aaauuagcag      840

gacuaauagg cagacauggu ccacaaaaca aacaaccauu caugguagca uuuuucaaag      900

caacagaagu ccauuucaga aguauaagau caacaggaag uaaacaaaga ucacaaaaca      960

gaucaaaaac accaaaaaau caagaagcac uaagaauggc uaacguagca gaaaauagcu     1020

cuagugacca aaggcaagcc uguaaaaaac acgaauuaua uguaucauuc agagauuuag     1080

gauggcaaga uuggaucaua gcaccagaag gauaugcagc auauuacugu gaaggagaau     1140

gugcuuuccc auuaaacuca uacaugaacg caacaaauca cgcaaucgua caaacacucg     1200

uacacuuuau uaauccagaa acaguaccaa aacccugcug cgcacccaca caauuaaacg     1260

caauaucagu acuauacuuu gacgauucau caaacguaau auuaaaaaaa uacagaaaca     1320

uggucguaag agcauguggu ugccauuaag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  3189
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt6)

<400>  3189
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaag       60

caucagcagc acuacuaugc cuacuacuaa cagcagcagc auucucacca caaggacuag      120

cacaaccagu aggaauaaac acaucaacaa caugcugcua cagauucaua aacaaaaaaa      180

uaccaaaaca aagacuagaa ucauacagaa gaacaacauc aucacacugc ccaagagaag      240

caguaauauu caaaacaaaa cuagacaaag aaauaugcgc agacccaaca caaaaauggg      300

uacaagacuu caugaaacac cuagacaaaa aaacacaaac accaaaacua uaaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  3190
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt6)

<400>  3190
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguuac       60

uaacuuugau aauauuauua ccaguuguuu caaaauuuuc uuuuguguca uuaucugcac      120

cgcaacacug gaguugucca gaaggaacuc uagcuggaaa uggaaauucu acauguguug      180

ggccugcacc auuucuaaua uucagccaug gaaacucaau uuucagaaua gauacugagg      240

gaaccaacua ugagcaacuc guugucgacg cuggaguauc uguaauaaug gauuuucauu      300

acaaugagaa acgcauauac uggguugacu uagaacgaca auuauuacaa agaguauuuc      360

uaaauggaag cagacaagaa aggguaugca auauagagaa aaaugugagu ggaauggcaa      420

ucaauuggau aaaugaagaa gugauauggu caaaccaaca agaaggaauu auaacaguaa      480

cagauaugaa aggcaauaau agccauauac uguugagcgc ccuuaaauau ccagcuaacg      540

uagcaguaga uccaguagaa agauuuauau uuuggaguuc ugaagucgca ggaucacuau      600

accgagcuga ccuugaugga guagguguaa aggcuuuacu agaaacauca gagaaaauca      660

cagcaguaag ucuugacgua cuagauaaaa gauuauucug gauccaauau aaccgcgaag      720

ggucuaauuc ccuuauaugu ucaugugacu acgacggagg cucaguacau auaucaaaac      780

auccgaccca acauaaucua uuugcuauga gccuuuucgg ggacagaauc uuuuauucga      840

cauggaaaau gaaaacaauu uggauagcaa auaaacacac aggaaaagac augguaagaa      900

uuaauuuaca uagcucuuuc guaccuuugg gagaauuaaa aguaguacau ccguuggcac      960

agccuaaagc agaagacgau acaugggaac cugaacaaaa auugugcaaa uugcgaaaag     1020

gaaacuguuc aucgaccguu uguggacaag acuuacaaag ucacuugugc augugugcgg     1080

aaggauaugc ucuauccaga gauagaaaau auugugaaga ugucaacgaa ugugcuuuuu     1140

ggaaucaugg augcacacua ggaugcaaaa acacaccagg uucuuauuac uguaccuguc     1200

caguagguuu uguuuuacua ccagacggua aaagauguca ccagcuagua ucguguccac     1260

gcaacguauc ugaauguucu cacgauugug uacuuaccag cgaaggacca uuauguuuuu     1320

guccggaggg aaguguacua gaacgugacg guaaaacaug uucaggaugc ucaucaccug     1380

auaacggugg uuguagucaa uuaugcgucc cacuuagucc uguaaguugg gaaugugacu     1440

gcuucccagg auaugauuug caauuagaug agaaaagcug ugcagccagc ggaccucaac     1500

ccuuucuccu uuucgcaaac agccaagaua uaagacauau gcauuuugau ggaacugauu     1560

auggaacgcu auuaagucaa caaaugggaa ugguuuacgc acuagaucau gauccuguag     1620

aaaauaaaau auauuuugcu cacacagccu uaaaauggau agaacgggca aauauggacg     1680

guagccaaag agaacgacua aucgaagaag gaguagaugu uccugaagga uuagcaguag     1740

auuggaucgg aagacgauuu uauuggacgg auaggggaaa aagccuaauu gguagauccg     1800

accuuaaugg aaaaagauca aaaauaauaa caaaagaaaa cauaagccaa ccacgcggaa     1860

uugcgguaca uccaauggca aaacggcuau uuuggacaga uacaggaaua aacccaagaa     1920

uagaaaguuc uucuuuacag ggacuaggac gucuaguaau agcaagcucc gauuuaauuu     1980

ggcccagugg uauaacgaua gacuuuuuaa cugauaaacu auacuggugu gaugcaaagc     2040

aaucagucau ugaaauggca aaucuagaug gaucuaaaag aagaagacua acucaaaacg     2100

auguaggaca cccauuugcc guagcaguau uugaagauua uguuugguuc ucagauuggg     2160

caaugccaag cguaaugaga guaaauaaaa gaacaggaaa agauagaguc agauugcaag     2220

gaagcauguu aaaaccgucc agucuugucg ucguucaucc ccuugcaaaa ccaggugcgg     2280

auccaugucu auaucaaaac ggaggaugug aacauauuug caagaaacgg uuagguacug     2340

cauggugcag cugucgagaa ggauucauga aagcgagcga ugguaaaaca uguuuagcac     2400

ucgauggaca ucaacuacua gcuggcggag aaguagaccu gaaaaaccaa gugacacccc     2460

uugauauacu uaguaaaacc agaguaagug aagauaauau aacggaauca caacauaugu     2520

uaguagcaga aaucauggug agcgaucaag augauugugc acccguagga uguaguaugu     2580

augcaagaug caucucagaa ggagaagacg caaccugcca gugcuuaaaa ggcuuugccg     2640

gcgacggcaa acugugcuca gauauugaug agugcgaaau gggugugccc guuuguccuc     2700

cagcgucauc caaauguaua aauacagaag gagguuaugu auguagaugc agcgaggguu     2760

aucaagguga uggcauacac uguuuggaua ucgaugaaug ucaauuagga gaacauucuu     2820

guggggaaaa ugcaaguugu acaaauacag aaggagguua uacuuguaug ugugcuggcc     2880

guuuaaguga accuggcuua auauguccag acagcacucc gccuccucac cuaagagagg     2940

augaucacca uuacagcgua cgcaauagcg auucagaaug cccucuaagu cacgacgggu     3000

acugucuaca ugacggagua uguauguaca uagaggcuuu agauaaguau gcauguaacu     3060

gugucguugg uuacauagga gaaagauguc aauaucgaga uuuaaaaugg ugggaauuaa     3120

gacacgcggg acauggccaa caacaaaaag uaauagucgu agccgucugc guaguuguuc     3180

uaguaauguu acuacuacug agucuuuggg gugcacacua uuauagaaca caaaaacuac     3240

uaucgaaaaa ucccaaaaau ccauaugaag aaagcaguag agauguaagg ucaagacgac     3300

cggcugacac agaagauggg augucaaguu gcccacaacc augguuugua guaauaaaag     3360

agcaucaaga ccuuaaaaac ggaggucagc caguagcugg agaagacggu caggcugcgg     3420

augggaguau gcaaccaaca ucuuggagac aagaaccuca acugugcgga auggguacgg     3480

agcaaggcug cuggaucccu gucagcucag acaaaggcag cuguccucaa gugauggaac     3540

gaucauucca uaugccguca uacgggacac aaacguugga aggaggagug gaaaaaccac     3600

auagucuauu auccgcaaac ccauuauggc aacaacgagc auuagaucca ccucaucaaa     3660

uggaauuaac ucaauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  3191
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt6)

<400>  3191
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugacag       60

cagguagaag aauggaaaug uuaugcgcag gaagaguacc cgcacuacua cuaugccuag      120

gauuccaccu auuacaagca guacuaucaa caacaguaau accaagcugc auaccaggag      180

aaucaucaga caacugcaca gcacuaguac aaacagaaga caauccaaga guagcacaag      240

uaucaauaac caaaugcuca ucagacauga acggauacug cuuacacgga caaugcauau      300

accuaguaga caugucacaa aacuacugca gaugcgaagu cggauacaca ggaguaagau      360

gugaacacuu uuuucuaaca guacaucaac cacuaucaaa agaauacgua gcacuaacag      420

uaauauuaau aauacuauuu cuaauaacag uagucggauc aacauacuac uucugcagau      480

gguacagaaa cagaaaauca aaagaaccaa aaaaagaaua cgaaagagua acaucaggag      540

acccagaacu accacaagua uaaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  3192
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt6)

<400>  3192
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

aaggagaaau aacaacauuc acagcacuaa cagaaaaauu caaccuacca ccaggaaacu      120

acaaaaaacc aaaacuacua uacugcucaa acggaggaca cuuccuaaga auacuaccag      180

acggaacagu agacggaaca agagacagaa gcgaccaaca cauacaacua caacuaucag      240

cagaaucagu aggagaagua uacauaaaau caacagaaac aggacaauac cuagcaaugg      300

acacagacgg acuacuauac ggaucacaaa caccaaacga agaaugccua uucuuagaaa      360

gacuagaaga aaaccacuac aacacauaca uaucaaaaaa acaugcagaa aaaaacuggu      420

ucguaggacu aaaaaaaaac ggaucaugua aaagaggacc aagaacacac uacggacaaa      480

aagcaauacu auuccuacca uuaccagucu caagcgacua aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  3193
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt6)

<400>  3193
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguug       60

ggguaggagg aggagacgua gaagauguaa caccaaggcc aggaggaugu caaauaagcg      120

gaagaggagc aagaggaugu aaugggauac caggagcggc agcaugggaa gcugcauuac      180

caagaagaag accuaggaga cauccaagug uuaauccaag aucuagagca gcggggaguc      240

caagaacaag aggaagaaga acagaagaaa gaccaagugg gucaagauua ggagauagag      300

guagggggag agcauuacca gguggaagau uaggagguag aggaagagga agagcaccag      360

aaagaguggg aggaagagga aggggaagag gaacagcagc accaagagca gcaccagcug      420

caagaggaag uagaccaggg ccggcaggaa caauggcagc aggaaguaua acaacauuac      480

cagcauuacc agaagacgga ggaucaggag cauuuccacc aggacauuuu aaagacccaa      540

aaagauuaua uuguaaaaac ggaggauuuu uucuaagaau acauccagau ggaagagucg      600

auggugugag ggaaaaaagu gauccgcaua uaaaauuaca auuacaagca gaagaacgag      660

gaguuguaag uauaaaagga guaugugcaa auagauaucu agcaaugaaa gaagauggaa      720

gauuauuagc aaguaaaugu guaacagacg aauguuuuuu uuuugaaaga uuagaaagca      780

auaauuauaa uacuuauaga aguagaaaau auacaagcug guauguagcu uuaaaaagaa      840

caggacaaua uaaacuagga aguaaaacag gaccaggaca aaaagcaaua cuauuucuac      900

caaugagcgc aaagucauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  3194
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt6)

<400>  3194
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aauggauacu aacauggaua cuaccaacac uacuauacag aagcugcuuc cacauaauau      120

gccuaguagg aacaauaagc cuagcaugca acgacaugac accagaacaa auggcaacaa      180

acguaaacug cucaucacca gaacgacaca caagaucaua cgacuacaug gaaggaggag      240

acauacgagu aagaagacua uucugcagaa cacaauggua ccuaagaaua gacaaaagag      300

gaaaaguaaa aggcacucaa gaaaugaaaa acaacuacaa cauaauggaa auaagaacag      360

uagcagucgg aaucguagca auaaaaggag uagaaucaga auucuauuua gcaaugaaca      420

aagaaggaaa acuauacgca aaaaaagaau gcaacgaaga cugcaacuuc aaagaauuaa      480

uacuagaaaa ccacuacaac acauacgcau cagccaaaug gacacacaac ggaggagaaa      540

uguucguagc acuaaaccaa aaaggaauac caguaagagg aaaaaaaaca aaaaaagaac      600

aaaaaacagc acacuuccua ccaauggcaa uaacauaagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  3195
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt6)

<400>  3195
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaac       60

uacuaccauc aguaguacua aaacuauuuu uagcagcagu acuaucagca cuaguaacug      120

gagaaucacu agaaagauua agaagaggac uagcagcagg aaccucaaau ccagacccac      180

caacaguaag cacagaccaa uuauuaccac uaggaggagg aagagacaga aaaguaagag      240

accuacaaga agcagaccua gaccuauuaa gaguaacacu aucaucaaaa ccacaagcac      300

uagcaacacc aaacaaagaa gaacacggaa aaagaaaaaa aaaaggaaaa ggacuaggaa      360

aaaaaagaga cccaugccua agaaaauaua aagacuucug cauacacgga gaaugcaaau      420

acgucaaaga acuaagagca ccaagcugca uaugccaccc cggauaccau ggagaaagau      480

gccacggacu aucacuacca guagaaaacc gacuauacac auacgaucac acaacaauau      540

uagcaguagu agcaguagua uuaucaucag uaugcuuacu aguaauagua ggacuauuaa      600

uguucagaua ccacagacga ggaggauacg auguagaaaa ugaagaaaaa guaaaacuag      660

gaaugacaaa uucacauuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  3196
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt6)

<400>  3196
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

uaacuaaacu uuuaccagcg uuauuacucc aacacguauu acuacaccuc cuauuauuac      120

caauagcuau accauaugca gaaggacaaa gaaaacgcag aaacaccaua caugaauuua      180

aaaaaucggc caaaacaacu cuaaucaaaa uagauccagc auuaaaaaua aaaacaaaaa      240

aaguuaacac agccgaucaa ugugcaaacc gcugcacacg uaauaaaggc cuaccauuca      300

caugcaaagc auuuguauuu gauaaagcac guaagcaaug ucuaugguuu ccauuuaaua      360

gcaugagcuc uggcguaaaa aaagaauuug gacaugaauu ugaccuauac gaaaauaaag      420

acuauauuag aaacuguauu auaggaaaag gaagaucaua uaagggcaca guauccauaa      480

caaaaucagg aauuaaaugu caaccauggu cauccaugau accccacgaa cauucauuuu      540

uaccaucaag uuauagagga aaagauuuac aagaaaacua uugccgaaac ccaagaggag      600

aagaaggcgg accuuggugu uuuacaucaa acccagaagu cagauaugaa guuugugaua      660

uaccccaaug uucagaagua gaauguauga cauguaaugg agaaucauau agaggucuaa      720

uggaucacac agaaaguggu aagauaugcc aaagauggga ucaucagaca ccacaccgac      780

auaaauuuuu acccgaaaga uacccugaua aaggauuuga ugauaauuac ugucgaaacc      840

cugaugggca gccaagacca ugguguuaua cuuuagaccc ccacacaaga ugggaauauu      900

gcgcuauaaa aacaugcgcg gauaauacaa ugaaugauac agauguaccc uuagaaacua      960

cugaauguau acaaggacaa ggugaggguu aucgcggcac ugucaauacu auauggaaug     1020

gcauccccug ucaaagaugg gauucacaau auccccauga acaugauaug acaccagaaa     1080

acuuuaaaug uaaagauuua cgagaaaauu auugccguaa uccagauggu ucagaaucuc     1140

ccuggugcuu uacaaccgau ccaaauauca gagucgggua cuguucacag auaccaaauu     1200

gcgacauguc ucauggucaa gauuguuaua ggggaaacgg aaaaaauuau augggaaacu     1260

uaucucaaac uagaucaggu uuaacuugua guauguggga uaaaaauaug gaagauuuac     1320

acagacauau auucugggaa ccugaugcaa gcaaacuaaa cgaaaacuac uguaggaauc     1380

cagacgauga ugcacauggc ccuuggugcu auacaggaaa uccauuaauc ccgugggauu     1440

auugucccau aucgcgaugu gaaggcgaca caacgccaac uauaguaaac cuagaucauc     1500

cagugauauc augugcaaaa acuaaacaau uaagagucgu aaauggaaua ccaacaagaa     1560

caaacauugg auggauggua ucacuccgau acagaaauaa acauauaugu ggaggaucau     1620

uaauaaaaga aagcuggguu uuaaccgcaa gacaauguuu uccaucucga gaccuuaaag     1680

acuaugaagc augguuagga auacacgacg uacaugguag aggagacgaa aaauguaaac     1740

aaguacuaaa uguuucccaa cuuguauaug guccagaagg uucagauuua guauuaauga     1800

aauuagcgag acccgcaguu uuagaugauu ucguaagcac cauagaccua ccgaauuaug     1860

gauguacuau accagaaaaa acaaguugua guguauacgg auggggauau acaggccuaa     1920

uaaauuauga cggauuacua agagucgcac acuuauauau aaugggaaac gaaaaauguu     1980

cacaacauca cagagguaaa guaacauuaa augaaaguga aauaugugca ggagcugaaa     2040

aaauaggcuc aggaccgugu gaaggagauu auggaggccc acuaguaugu gaacagcaca     2100

aaaugagaau gguacuagga guaauaguac caggccgagg augugcaauc ccaaacagac     2160

caggaaucuu uguuagaguc gcuuacuaug cuaaauggau acauaaaaua auacuaacau     2220

auaaaguacc acaaucauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  3197
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt6)

<400>  3197
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcaa       60

aagcagcagc aauuggaaua gauuugggua caacauacag uugcgugggc guguuucaac      120

acggaaaagu agaaauaaua gcaaacgauc aaggaaacag gacaacacca ucauacgugg      180

cauuuacaga cacagaacga uuaauagggg acgcugcuaa aaaccaagua gcauuaaacc      240

cccaaaacac aguguucgau gcgaaaaggc uuauaggucg gaaauuuggg gaucccguag      300

uccaaagcga uaugaaacau uggccauucc aagucauuaa ugauggagau aaaccaaaag      360

ugcaaguaag uuacaagggu gaaacaaaag cauuuuaccc ggaagaaaua ucaaguaugg      420

uacuaacuaa aaugaaggaa auagcugaag cauaccuagg auacccagua acaaaugcgg      480

uaauaacagu gccagccuac uuuaacgauu cgcaacgaca agcaacgaaa gacgcagggg      540

ucauagccgg ucuaaauguc uuaagaauaa uaaaugaacc aacagcagca gcgauagcuu      600

acggacuaga uagaacagga aaaggugaaa gaaacguacu aauauuugau uugggaggag      660

gaacauuuga cguaucgaua uuaaccauag augacggcau auuugaagua aaggcaacgg      720

caggagacac acaucuggga ggagaagacu uugauaaucg gcuaguaaau cacuuugucg      780

aagaauuuaa aagaaaacac aagaaagaua uaagucaaaa caaaagagca guaagaagac      840

uuagaaccgc cugcgaaaga gcaaaaagaa cacuaagcuc aucaacacaa gcaaguuugg      900

aaauagauuc auuauuugaa gguauagacu ucuauacuuc aauuacaaga gccagauucg      960

aagaacuaug uagugauuua uuuagaagua cguuagaacc gguagaaaaa gcguuaagag     1020

augcuaaacu agauaaagcu caaauccaug aucuaguauu aguaggagga aguacaagaa     1080

uaccaaaagu gcaaaaauua cuucaagauu ucuuuaacgg aagagaucua aauaaaucga     1140

uaaauccaga ugaagcggua gcguacggag cagcaguaca agcagcaaua uugaugggag     1200

auaaaaguga aaacguucaa gauuuauuau uacuagaugu agccccauua aguuuaggac     1260

ucgagacagc ugguggaguu augacagcgc uaauaaaaag gaacucaaca auaccaacaa     1320

aacaaacaca aauauuuaca acauauagug auaaucaacc aggaguacua auacaaguau     1380

augaaggaga aagagcgaug acaaaagaca auaauuuacu uggaagauuc gaacuuagug     1440

gaauaccacc agcaccacga ggaguaccac aaauagaagu aacguuugau auugacgcaa     1500

acggaauacu aaauguaacc gcuacagaua aaagcacagg aaaagcaaac aaaauaacua     1560

uaacaaauga uaaagguaga uuaaguaaag aagaaauaga acguauggua caagaagcag     1620

aaaaauacaa agcagaagac gaaguacaaa gagaaagggu cagcgcgaaa aaugcacuag     1680

aaaguuacgc auucaauaug aaaagugcag uagaagauga aggacucaaa ggaaaaauaa     1740

gugaagcaga uaaaaagaaa gucuuagaua aaugucaaga agugauaagc uggcuagaug     1800

caaauacauu agcugaaaaa gacgaauuug aacauaaaag aaaagaacua gagcaaguau     1860

gcaacccaau aauaaguggc uuguaccaag gggcaggagg accggggcca ggaggcuuug     1920

gagcucaagg accuaaagga ggaagcggua gcggaccaac aauagaagaa guagacuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3198
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt6)

<400>  3198
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcaa       60

aagcagcagc gauaggaaua gauuuaggga caacuuauag uuguguagga guauuccaac      120

auggaaaagu agaaauaaua gcuaaugacc aaggaaauag aacaacuccu aguuauguag      180

cauuuacaga cacagaaaga cuaauaggag acgccgcuaa aaaucaagua gcccucaauc      240

cacagaauac aguauucgac gcaaaaagac uuauagguag gaaauucgga gauccagugg      300

uacaaagcga uaugaaacau uggccauuuc aaguaauaaa ugacggagau aaaccaaaag      360

uacaaguauc auacaaagga gaaacaaaag cauuuuaucc ugaagaaauc ucaaguaugg      420

uacuaacaaa gaugaaggaa auugcagaag cauaucuugg auacccagua acgaacgcag      480

uaauaacagu accugccuac uuuaacgaca gccaacguca agcaacuaaa gacgcaggag      540

uaauagcugg ucuaaacgua cuuagaauua ucaaugaacc aacugcagcc gcaaucgcau      600

acggacuaga ccgaacggga aaaggagaaa ggaauguauu aauuuucgac cuaggaggag      660

gaacauucga ugucucuaua uuaacuauag acgauggaau uuuugaagua aaagcaacgg      720

caggagacac gcauuuagga ggagaagauu ucgauaaccg ucuaguaaau cauuucguug      780

aagaauuuaa aagaaaacau aaaaaggaca uuucgcaaaa uaaaagagca gugagaagau      840

uaagaaccgc cugugaaaga gcaaaaagaa cauuaagcag caguacgcaa gcaagccuug      900

aaauagauuc acuauuugaa ggaauagauu ucuacacauc aauaacaaga gcucgauuug      960

aagaauuaug uagcgacuug uucagaucaa cauuagagcc aguagaaaaa gcacuaagag     1020

acgcaaaauu agacaaagca caaauacaug accuaguauu aguuggaggc aguacacgaa     1080

uaccaaaagu acaaaaacuu cuacaagacu ucuuuaaugg aagagaucua aauaaaucaa     1140

uaaauccaga ugaagcagua gccuacggug cggcgguuca agcagcaaua cugauggggg     1200

acaaaucaga aaauguacaa gauuuauuau uauuagaugu ggcaccacua ucauuaggau     1260

uagaaacagc uggaggugua augacagcac uaauuaaacg aaacagcacc auaccaacga     1320

aacaaacaca aauauuuacc acguacucgg acaaucaacc gggaguauug auacaaguau     1380

acgaaggaga aagagcaaug acuaaagaca acaaucuauu aggaagauuc gaauuaucag     1440

gaauaccgcc agcaccaaga ggaguaccac aaauagaagu aacauucgau auagacgcaa     1500

auggcauuuu aaacguaaca gcaacagaca aaucaacagg uaaagcaaac aaaauaacaa     1560

uaacaaauga uaaaggaaga cuaucuaaag aagaaauaga aagaauggua caagaagccg     1620

aaaaauacaa agcagaagau gaaguucaaa gagaacgugu gagugccaag aaugcacuug     1680

aaucguaugc guucaauaug aaaagcgcag uagaagauga gggccuaaaa ggaaaaauau     1740

cagaagcaga caaaaagaaa gucuuggaua agugucaaga aguaauaagu ugguuagaug     1800

caaacacacu cgcagaaaaa gaugaauuug aacauaaaag aaaagaacua gaacaaguau     1860

gcaauccaau aauaucaggg uuauaccaag gagcaggcgg accaggaccc gggggauucg     1920

gugcccaggg accaaaaggc gguaguggca gcggaccaac cauugaagaa guagauuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3199
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt6)

<400>  3199
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcua       60

cagcaaaagg aauagcaaua ggaauagauu uaggaacaac auauucgugu guuggaguau      120

uccaacacgg aaaaguagaa aucauagcaa augaccaagg aaacagaaca acaccaagcu      180

auguagcauu uacggauaca gaaagauuaa uaggagacgc agccaaaaac caaguagcua      240

ugaauccaca aaauacagua uucgaugcaa aaagacuaau aggaagaaaa uuuaaugacc      300

caguaguaca agcagauaug aagcuauggc ccuuccaagu uauaaaugaa ggagggaaac      360

caaaaguucu aguaaguuau aaaggugaaa auaaagccuu cuauccagaa gaaauaucaa      420

gcaugguccu aacaaaacua aaagaaaccg cagaagcauu cuuaggacau ccugucacua      480

acgcaguaau aacaguacca gcauacuuca acgauaguca acgucaagca acaaaagaug      540

cuggaguuau agcaggacua aauguacuac gaauaaucaa cgaaccgaca gcagcagcua      600

uagcauaugg acucgacaaa ggcggacaag gagaaagaca cgugcucauc uucgacuuag      660

gcgguggcac auuugaugua uccauacuaa ccauugacga uggaauuuuc gaaguaaaag      720

ccacagccgg agacacccau cuagggggag aagauuucga uaaccgguua guaagucacu      780

ucguagaaga auuuaaaaga aaacacaaga aagauauaag ucaaaauaaa cgagcaguaa      840

gaagauuaag aacagcaugu gaaagagcca aaagaacacu uaguaguuca acacaagcaa      900

acuuagaaau agauucauua uacgaaggaa uagauuucua uaccaguaua acaagagcaa      960

gauuugaaga acuaugcgcu gauuuauuuc gcggaacauu agaacccguc gaaaaagcau     1020

uaagagaugc aaaaauggau aaagcaaaaa uacacgacau aguauuagug ggagguagca     1080

cgcgaauacc aaagguucaa cgauuauuac aagacuauuu uaauggcaga gaccucaaua     1140

aaaguauaaa cccugaugaa gcaguugcau acggagcugc aguacaagca gcuauacuga     1200

ugggagacaa aucagaaaaa guacaagauc uccuacuacu agacguagcu ccacuaucac     1260

ugggucuuga gacagcggga ggcguaauga cagcauuaau uaaaaggaac ucgaccauac     1320

ccacaaaaca aacacaaaua uuuaccacau auucagauaa ccaaccugga gugcuuauuc     1380

aaguauacga aggagaaaga gcaaugacga aagauaauaa cuugcuagga agauuugauc     1440

uaacagggau uccaccagca ccaagaggcg ugccacaaau agaagucacc uucgacauag     1500

acgcaaacgg aauauuaaac gucacagcaa ccgauaaauc aacagguaag gucaauaaaa     1560

uuacaauaac aaacgauaaa ggaagacuau caaaagaaga aauagaaaga augguacuag     1620

augcagaaaa auacaaagca gaagacgaag uacaaagaga gaaaauagca gcuaaaaacg     1680

cgcuagaaag uuacgcauuu aacaugaaaa guguaguauc ugaugaagga uuaaaaggca     1740

aaauuucaga aagcgauaaa aauaaaauac uagacaaaug caaugaacua cuuaguuggu     1800

uagaaguaaa ucaacuagcc gaaaaggaug aauuugacca uaaaagaaaa gaacuggaac     1860

aaauguguaa ucccaucaua acaaaacuau aucaaggagg cugcacagga ccagcaugug     1920

gaaccggaua uguaccagga cguccagcaa caggaccaac aauagaagaa guagacuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3200
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt6)

<400>  3200
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucag       60

caagaggacc agcaauuggg auagaucuag gcacaacuua cucaugcgua gguguauucc      120

aacacggaaa aguagaaauu auagcaaacg aucaagggaa cagaacaaca ccaaguuaug      180

uagcauuuac agacacugaa agauuaauag gugacgcagc uaaaaaucaa guagcaauga      240

acccuacaaa cacaauuuuu gacgcaaaac gacuaaucgg aagaaaauuc gaagacgcaa      300

caguacaauc agauaugaaa cauuggccgu ucagaguagu aagcgaagga gggaaaccaa      360

aaguacaggu ugaauacaaa ggagaaacaa aaacuuucuu cccagaagaa auuaguagua      420

ugguccucac aaaaaugaaa gaaauagcag aagcauaccu uggaggaaaa guucacucag      480

caguaauuac aguaccagca uacuucaacg auucccaaag acaagcaacg aaagacgccg      540

guacaauaac aggauuaaac guguuaagaa uuauaaacga accuaccgca gcagccauag      600

cguauggauu agauaagaaa ggaugugcag gaggagagaa aaauguauua auauuugacu      660

uaggcggugg gacauuugau guaaguauac ugacaauaga agaugggaua uuugaaguca      720

aaucgacagc aggagacaca cauuuagggg gagaagacuu ugacaacaga augguaagcc      780

aucuagcaga agaguucaaa agaaaacaca agaaagacau aggacccaau aaaagagcug      840

ucaggagacu uagaacagca ugcgaaagag caaaaagaac auuaucaagu ucaacacaag      900

caaguauaga aauagauucg cuauaugaag gaguugauuu cuauacaagu auaacaagag      960

caagauuuga agaacuaaac gccgaucuau uuagaggaac auuagaaccg guugaaaaag     1020

cacuuagaga cgcaaaauug gauaaaggcc aaauacaaga aauuguucua guaggaggaa     1080

guacacgcau uccaaaaaua caaaaacuau uacaagacuu uuucaaugga aaagaacuca     1140

auaaaucaau aaacccugau gaagcgguag cguauggugc agccguacaa gccgcaauau     1200

uaaucggaga caaaagugaa aacguacaag accuacuauu guuagaugua acaccauuau     1260

cacucggaau ugaaacagcu ggaggaguaa ugacaccacu cauaaaaaga aauacaacca     1320

uucccacaaa acaaacacaa acauucacaa cguacagcga uaaccaaagu agcguccuag     1380

uacaaguaua ugaaggcgaa agagcaauga ccaaagacaa caaucuauua ggaaaauucg     1440

acuuaacagg aauaccucca gcaccaaggg gaguaccaca aauagaaguu acauuugaca     1500

uagaugcuaa cggaauauua aacguaacag cagcagauaa aagcacagga aaagagaaua     1560

aaauaacaau uacaaacgau aaaggaagac uaagcaaaga cgauauagau agaaugguac     1620

aagaagcaga aagauauaaa agcgaagacg aagcuaacag ggaucgaguc gcagccaaaa     1680

augcauugga aagcuauaca uacaauauaa aacaaacugu agaagaugaa aaauuaagag     1740

gaaagauaag ugaacaagau aaaaauaaaa uuuuagacaa augucaagaa guuauaaacu     1800

gguuagauag aaaccaaaug gccgaaaaag acgaguacga acauaaacaa aaagaacuag     1860

aaagagucug uaaucccaua auuagcaaau uauaccaagg aggacccgga gguggaagug     1920

gaggaggagg aucaggagca agcggaggcc caacaauaga agagguugau uaaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  3201
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt6)

<400>  3201
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

ugguagguau agaucuugga uuccaaucau guuacguugc cguagcaaga gcaggaggaa      120

uagaaacaau agccaacgaa uacagugaca gauguacacc ggccugcaua uccuuuggac      180

cuaaaaacag aucaaucggc gcagccgcaa aaucacaagu gauuucaaau gcuaaaaaca      240

cagugcaagg uuucaaaaga uuccacggac gagcauuuag cgacccauuu guugaagcag      300

aaaaaucaaa cuuagcuuau gauaucguac aauuacccac aggacuaaca gguauaaaag      360

ucacauauau ggaagaggaa agaaacuuca caaccgaaca aguaaccgcg augcuauuau      420

caaaacucaa agaaacagca gaauccgucu uaaagaaacc ugucguugac uguguaguau      480

caguacccug cuucuacaca gacgcagaaa gaagauccgu aauggaugcc acacaaauag      540

cuggucugaa uugcuuacga cuaaugaaug aaacgacggc aguugcauua gcuuacggaa      600

uauauaaaca agacuuaccc gcacuagaag aaaaaccaag aaacgucgua uuuguagaua      660

ugggucacag ugcauaucaa guguccguau gugcuuuuaa cagagguaaa cuaaaaguau      720

uagcaacagc uuuugauacu acuuuaggcg gacgaaaauu ugaugaaguu cuaguaaauc      780

auuuuugcga agaauuuggu aagaaauaca aacucgauau caaaucaaaa auacgugcau      840

uauuacgacu uucacaagaa ugugaaaaac uaaagaaauu aaugagugca aacgcaagcg      900

accugccuuu aucuauagaa uguuucauga acgauguaga uguaucgggc acaaugaaca      960

gagguaaauu ccucgaaaug ugcaacgauc uguuagcaag aguagaacca ccacuacgaa     1020

guguauuaga acaaacaaaa cuaaagaaag aagacauuua ugcaguagaa auaguuggag     1080

gggcaacacg aauaccagcg guaaaagaga aaauuucaaa auucuuuggc aaagaauuau     1140

caacuacacu uaaugcagau gaagccguaa cuagaggaug ugcacuccaa ugugcaauau     1200

uaucaccagc uuucaaagua agagaauuua gcauaacaga uguaguacca uacccaauuu     1260

cacugagaug gaacucacca gcagaagaag ggucauccga cugcgaagua uucaguaaaa     1320

aucaugcugc cccuuuuuca aaaguacuaa cauucuauag aaaagaaccu uuuacccuag     1380

aagcauacua uucaucaccc caagaucuuc cauaccccga uccagcaaua gcccaauuua     1440

gcgugcaaaa aguuacaccu caaagugaug gaucaagcag uaaaguuaaa guaaaagucc     1500

gugugaacgu ucaugguaua uuuaguguau cuucagccag ccuaguagaa guacacaaaa     1560

gcgaagaaaa ugaagaacca auggaaacgg aucaaaaugc uaaagaagaa gagaaaaugc     1620

aaguagacca agaagaacca cauguagagg aacaacaaca acaaacaccc gcagaaaaca     1680

aagccgaaag ugaagaaaug gaaacaucuc aagcaggauc aaaggauaag aaaauggauc     1740

aaccuccuca agcgaagaaa gcaaaaguaa aaacaucuac agucgaucuu ccaauagaaa     1800

accaacuuuu auggcaaauc gauagagaaa uguuaaaccu auauauagaa aacgaaggaa     1860

aaaugauaau gcaagacaaa uuagaaaaag aaagaaacga cgcuaaaaac gcaguagaag     1920

aauauguuua ugaaaugaga gauaaacuga gcggagaaua cgaaaaauuc guaagcgaag     1980

acgaucgaaa uucauucacc cuaaaacuug aagacacuga aaacuggcuc uacgaagaug     2040

gagaagacca accaaaacaa guauacguag auaaacuagc agaacugaaa aaccuaggac     2100

aaccaauaaa aauaagauuc caagaaagug aagaacgucc uaaauuauuc gaagaacuag     2160

gaaaacaaau acaacaauau augaaaauca uaucaaguuu uaaaaacaaa gaagaucaau     2220

acgaccacuu agaugccgca gacaugacaa aaguagaaaa aucuacuaac gaagccaugg     2280

aauggaugaa uaauaaauua aaccuccaga acaaacaauc gcuaacaaug gauccagugg     2340

ucaaaucaaa agaaauagaa gcaaaaauua aagaacuaac aaguacuugc ucaccaauca     2400

uaagcaaacc aaaacccaaa gucgaaccac caaaagaaga acagaaaaac gcagaacaaa     2460

auggaccagu agacggccaa ggugacaacc caggaccaca agcagcggaa caagguacug     2520

acacagcagu acccucagac agugauaaga aacuaccaga aauggauaua gacuaaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  3202
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt6)

<400>  3202
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucag       60

uagucggaau ugaccuugga uuuuuaaacu gcuacauagc aguagcuagg ucaggaggaa      120

ucgaaacaau agcaaacgaa uauagcgaua gaugcacccc ugccugcaua ucauuaggau      180

cacgcacuag agcaaucggg aacgcagcca aaucacaaau aguuacaaac guaagaaaua      240

caauccacgg auucaaaaaa cuacacggca gguccuuuga ugauccaaua guacaaacgg      300

aaagaauaag acuacccuac gaacugcaaa aaaugcccaa uggaagugca ggcgucaaag      360

ucagauaucu agaagaagaa agaccuuuug caauagaaca aguaaccgga auguuauugg      420

cuaagcuaaa agaaacuuca gaaaacgcau uaaagaaacc uguagcagau uguguuauau      480

caauaccauc guuuuucaca gaugcagaac gaagaucagu aauggcagca gcacaaguag      540

ccggccuaaa cugucuucga cuaaugaaug aaacaacugc aguugcccua gcuuauggaa      600

uuuauaaaca agauuuaccu ccucuagacg aaaaacccag gaacguagua uucauagaua      660

ugggucauag ugcauaucaa guucuagugu gugcauuuaa uaaaggaaaa uuaaaagucc      720

uagcaacaac auucgauccg uaucuaggag ggcgaaacuu cgaugaggca cugguagacu      780

acuuuuguga cgaauucaaa acgaaauaca agauuaacgu aaaagaaaac agcagagcuc      840

uucuaaggcu auaccaagaa ugugaaaaac ucaaaaaauu aauguccgcu aaugccucag      900

accuaccacu aaauauagaa uguuucauga augauuuaga ugugucaagu aaaaugaaca      960

gagcacaauu ugaacaauua ugcgcaucau uacuagcucg aguagaacca ccauuaaaag     1020

ccguaaugga acaagcuaau uuacaacgag aagauaucuc aucaauagaa aucguuggag     1080

gagccaccag aauuccagcg guaaaagaac aaauuacuaa auuuuuucuu aaagacaucu     1140

caacaacacu aaaugcugac gaagcaguug cccggggaug cgcccuccaa ugugcaauac     1200

uuagcccugc auuuaaagua cgagaauuuu caauaacaga cuuaguucca uauucgauca     1260

cauuaagaug gaaaacauca uucgaagacg gcagcggcga augugaagua uucugcaaaa     1320

accacccagc cccuuuuagc aaaguaauaa cauuucauaa aaaagaaccg uuugaauuag     1380

aagcauuuua cacaaacuua cacgaaguac cauacccuga ugcacgaaua gguagcuuua     1440

cuauacaaaa cguauuccca caauccgaug gcgacagcuc aaaaguuaaa guaaaaguca     1500

gaguaaacau acauggaauu uucucugucg caucagcauc uguuaucgaa aaacaaaauc     1560

uagaagggga ccauuccgac gccccaaugg aaaccgaaac aagcuuuaaa aaugaaaaca     1620

aagacaauau ggauaaaaug caaguagauc aagaagaagg acaucaaaaa ugccaugcug     1680

agcauacacc agaagaagag auagaccaca cuggggcaaa aacaaaauca gccguuucag     1740

auaaacaaga uagauuaaau caaacacuaa aaaaaggcaa gguaaaaucu auugauuuac     1800

caauccaauc cucacucugc agacaauuag gacaagaucu auuaaauagc uauauagaaa     1860

augaaggaaa aaugaucaug caagacaaac uagaaaaaga aagaaacgac gccaaaaaug     1920

caguugaaga auacguauau gauuucaggg accgacuagg aaccguuuau gaaaaauuua     1980

uaacgccaga agaccuuuca aaacuaagug caguauuaga agacacagag aacugguuau     2040

augaagaugg agaagaccaa ccaaaacaag uauacguuga caaauuacaa gaacuaaaga     2100

aauacggaca accaauacaa augaaauaca uggagcacga agaacgucca aaagcacuaa     2160

acgaccuagg caaaaagauc caacuuguaa ugaaaguaau agaagcuuau agaaauaaag     2220

augaacggua ugaccaucuu gaccccacag aaauggaaaa aguugaaaaa ugcauaagcg     2280

acgcaaugag cuggcucaac agcaaaauga acgcacaaaa caaauuauca cuaacacaag     2340

auccaguagu aaaagucagu gaaauaguag caaaaucaaa agaacuagac aauuucugua     2400

auccaauaau auacaaaccc aaaccaaaag ccgaaguccc cgaagacaaa ccaaaagcaa     2460

acucagaaca uaauggucca auggauggac aaucuggaac agagacaaaa ucagacucaa     2520

cuaaagauuc aucccaacau accaagagua gcggggaaau ggaagucgac uagggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  3203
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt6)

<400>  3203
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

uaaguuuggu ggcagcaaug cuauuauuau uaagcgcugc aagagcagaa gaagaggaua      120

aaaaagaaga uguugguacg gugguuggaa uugaccuugg aacaacauac agcugugucg      180

gaguauuuaa aaauggaaga guugaaauua uagcuaacga ucaggggaau agaauaacac      240

caaguuacgu agcauucaca ccagagggag aaagauuaau cggagacgca gcaaaaaacc      300

aacuuacuag uaauccagaa aauacaguau ucgaugcaaa aagauuaaua ggaagaacau      360

ggaacgaccc uuccguacaa caagauauca aauuccuacc auuuaaaguu guagaaaaaa      420

agacaaaacc auacauacaa gucgauauag gaggaggaca aacaaaaaca uuugcgccag      480

aggaaaucag ugcaauggua uuaacuaaaa ugaaagagac agcagaagca uacuuaggua      540

aaaaaguaac acacgcagua gucacaguac cagcauauuu uaacgacgca caaagacaag      600

caacaaagga ugcaggaaca aucgcaggau uaaacguaau gagaauaaua aaugagccaa      660

cagcagcagc aauugcauau ggauuagaca aacgagaagg ugagaaaaac auccugguau      720

ucgacuuagg agggggcaca uuugacguaa guuuauuaac uauagauaau ggaguauuug      780

aaguaguagc aacaaacggu gacacacauu uaggaggaga agauuucgau cagagaguaa      840

uggaacauuu uauaaaauua uacaaaaaaa aaacaggaaa agauguaagg aaagacaaua      900

gagcagugca aaaacuuagg agagaagucg aaaaagcaaa acgagcccua aguagccaac      960

aucaagcaag aauagaaaua gaaagcuuuu augaagggga agacuucagu gaaacacuua     1020

cgagagcaaa auuugaagaa uuaaacaugg accuauuuag aagcacaaug aaaccuguac     1080

aaaaagugcu cgaagauuca gaccuaaaaa aaagcgacau agaugagauu gucuuaguag     1140

gaggaaguac aagaauucca aaaauccaac aacuaguaaa agaauuuuuc aauggaaaag     1200

aaccuaguag aggaauaaac ccagacgaag caguagcaua uggagcugca guacaagcug     1260

gaguucuaag uggcgaccaa gacacaggag acuuaguauu acuagacgua uguccguuaa     1320

cauuaggaau agaaacagua ggaggaguaa ugaccaaauu gauaccuagg aacacuguug     1380

uaccaacgaa aaaaucacaa auauuuagua cagcaucaga uaaccaacca acuguaacua     1440

uaaaaguaua cgaaggagaa aggccucuaa caaaagacaa ucaccuucug ggaaccuuug     1500

aucucacagg aauaccacca gcaccacggg gaguaccgca aauagaagua acauucgaaa     1560

uagacgucaa cgguauucua agaguaacgg ccgaagauaa aggaacagga aacaagaaua     1620

agauaacuau uacaaaugac caaaaucgau uaacuccaga agaaauagaa cgaaugguca     1680

acgacgcaga aaaauuugcc gaagaagaua aaaaauuaaa agagagaaua gauacucgaa     1740

acgaacuaga aaguuacgcc uacucacuca aaaaccaaau cggggauaaa gaaaaguuag     1800

gagguaaauu aucaagugaa gauaaagaaa caauggaaaa agcagucgaa gaaaaaauug     1860

aauggcuaga aucacaccaa gacgcagaua uagaagauuu caaagcaaaa aaaaaagaau     1920

uagaagaaau uguacaaccc auaauuagua aauuauaugg aagugcaggg ccaccaccaa     1980

caggcgaaga agacacagca gaaaaagaug aauuauaagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  3204
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt6)

<400>  3204
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

caccaagaga acuagcggua ggaauagauu uaggaacaac uuacucaugu guaggaguau      120

uucaacaagg aagaguagaa auauuagcaa augaccaagg aaauagaaca acacccucau      180

acguagccuu uacagacacc gaacgauuag uaggagaugc agcaaaaagc caagcagcac      240

ucaacccaca uaauacgguc uuugacgcaa aaagauuaau aggccgaaaa uuugcggaua      300

cuacaguaca aagugauaug aaacacuggc ccuuucgagu aguaucugaa ggaggaaaac      360

cgaagguaag aguauguuau cgaggagaag acaaaacauu cuauccagaa gaaauaucuu      420

cuaugguauu gucgaaaaug aaagaaacgg cugaagcgua ucuaggacaa ccaguaaaac      480

augcaguaau aacuguacca gcuuacuuua augauagcca gagacaagca acaaaagaug      540

caggagccau agcaggauua aauguauuga ggauaauaaa ugaaccaacu gcagccgcaa      600

uagcauacgg guuagaccga agaggagccg gugaaagaaa ugucuuaaua uuugauuugg      660

gcggaggaac auuugaugua aguguauuau caauagacgc aggaguuuuu gaagucaaag      720

caacggcagg agacacacau uuaggagggg aagacuuuga uaauaggcua guaaaucauu      780

ucauggaaga auuucgaaga aaacacggaa aagauuuauc uggaaauaaa cgagcuuuaa      840

gaagguuaag aacagccugu gaaagagcaa aaagaacauu aucaucaagu acacaagcaa      900

cauuagaaau ugacucacuc uucgaaggag ucgacuucua uacaucaaua acacgagcaa      960

gauuugaaga acuaugcuca gaucuauuuc gaucaacauu agaaccagug gaaaaagcau     1020

ugcgggaugc gaaauuagac aaagcacaaa uacaugacgu aguuuuagua ggcggcucaa     1080

caagaauacc aaaagugcaa aaacuauuac aagauuucuu caacgggaaa gaauuaaaca     1140

aaucaauuaa uccggaugaa gcuguagcuu auggagcagc aguucaagcc gccgucuuaa     1200

ugggagacaa augcgaaaaa guucaagauu uauuacuacu agauguggca ccacucucuc     1260

uuggucucga aacagcggga ggaguuauga cuacguuaau ccaaagaaau gcaacaauuc     1320

caacaaaaca aacccagaca uucacaacau acucugauaa ucaaccagga gucuuuauac     1380

aaguuuacga aggcgaacga gcaaugacaa aagauaauaa uuuauuggga agauuugaac     1440

uuucaggaau acccccagca ccuagaggag uaccucaaau agaaguaacc uucgacauag     1500

acgcuaaugg aauacuuagc guaacugcaa cugauagaag uacaggaaaa gcaaacaaaa     1560

uaacaauaac aaacgauaaa ggccgacuaa gcaaagaaga aguagaaaga augguacaug     1620

aagcugaaca auacaaagcc gaagaugaag cacaacgaga uagaguugca gcuaaaaaua     1680

gucuagaggc acauguauuu cauguaaaag gcagccuaca agaagagagc uuaagagaca     1740

aaauaccaga agaagacaga agaaaaaugc aagauaagug uagagaagua uuggcauggu     1800

uagaacauaa ucaauuagca gaaaaagaag aauaugaaca ucaaaaacga gaauuagaac     1860

aaauaugucg accaauauuu ucaagguuau auggaggccc aggaguacca gggggaaguu     1920

caugugguac acaagcaaga caaggugauc cgucaacagg accaaucauc gaagaaguag     1980

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  3205
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt6)

<400>  3205
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

caccaagaga auuagcugua ggaauagacu uaggaacaac auauuccugu guaggaguau      120

uucaacaagg aagaguagaa auuuuagcaa augaucaagg aaauagaaca acaccaucau      180

auguagcauu uacugauacc gaaagauuag ucggagaugc agcaaaguca caagcagcau      240

uaaauccuca caauacaguu uuugaugcaa aaagauuaau aggaagaaaa uucgcugaua      300

caacaguaca aagcgacaug aaacauuggc cauuccaagu uguaagcgaa gguggaaaac      360

caaaaguacg aguauguuau agaggagaag acaaaacauu cuaccccgaa gaaauaucaa      420

guaugguucu aucaaaaaug aaagaaacag cagaagcaua uuuaggacaa ccaguuaaac      480

augcaguaau aaccguucca acauauuuua gcaauaguca aagacaagca acuaaagaug      540

caggagcaau agcaggacuu aaaguacugc caauaauaaa ugaagcaaca gcagcagcaa      600

uagccuaugg ccuagacaga agaggagcug gaaaaagaaa cguauuaaua uuugauuuag      660

gaggaggaac uuuugaugua aguguauuaa guauugacgc aggcguuuuu gaaguaaaag      720

caacugcugg ugauacucac uuggguggag aagauuuuga uaauagauua guaaaucauu      780

uuauggaaga auuuagaaga aaacacggaa aagaucuaag uggaaauaaa agggcauuga      840

gaagauuaag aacagcaugu gaaagagcaa aaagaacacc uagcucaagu acacaagcaa      900

cgcuagaaau agauucauua uucgaaggag uagauuuuua uaaaucaauc acaagggcaa      960

gauuugaaga auuaugcagu gacuuauuca ggagcacauu agaaccagua gaaaaagcau     1020

uaagagaugc aaaauuagau aaagcacaaa uacaugauuu ugugcuagga gggggauuac     1080

auucacaucc acaaggagca gaaguugcag caggauuauu acaaagacaa ggagcagaac     1140

aagaacacca accauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  3206
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt6)

<400>  3206
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagca       60

aagggccagc aguaggaaua gauuuaggua ccaccuacag cuguguagga guauuccaac      120

acggaaaagu ggaaauaaua gcaaaugacc aaggcaauag gacaacacca ucauacguug      180

cauucacaga uaccgagcga cuaauuggag augcagcuaa aaaucaagua gcaaugaauc      240

caacaaauac gguauuugac gcaaaaagac uaauaggcag gagguuugau gacgcaguug      300

uacaaagcga uaugaaacac uggccauuua ugguaguaaa ugaugcugga agaccaaaag      360

uacaaguaga auacaaaggc gaaacuaaaa guuucuaccc cgaagaagua ucuucaaugg      420

uauuaacaaa aaugaaagaa aucgcagaag cauacuuagg aaaaacgguu acaaacgcag      480

uaguaacagu accagcauau uuuaacgacu cccaaaggca agcaacaaaa gacgcuggga      540

caauugccgg gcuuaaugua uuaagaauca uaaaugaacc aacagcagca gcaauagccu      600

acggauuaga uaagaaagua ggugcagaaa gaaacguauu aauauuugac uuaggcggug      660

gaacauuuga uguaucaaua uuaacaauag aagacggaau auuugaagua aaaucuacag      720

cuggagacac acaccuagga ggagaagauu ucgauaacag aaugguaaau cauuuuauag      780

ccgaauuuaa aaggaaacau aagaaagaua uaagugaaaa uaaaagagca guaagaagau      840

uaagaacagc augcgagcga gcgaaaagga cuuuaucauc gagcacacaa gcaagcauag      900

aaauugauag ccuauaugaa gguauagacu uuuacacauc aauaacaaga gcccgauucg      960

aagaauuaaa cgcagaucua uuuagaggaa cguuagaccc aguagaaaaa gcauuaagag     1020

augcaaaauu agauaaaagc caaauacaug acaucguauu gguuggagga ucuacaagaa     1080

uaccuaaaau acaaaaauua cuacaagacu ucuuuaacgg caaagaauua aacaaaucaa     1140

uaaauccaga cgaagcagua gcguauggug cggcgguaca agccgcuaua uuauccggag     1200

acaaaaguga aaacguacaa gaucuacuau uacuagacgu aacaccccua ucauuaggaa     1260

uugaaacagc aggaggagua augacaguuu uaauaaaaag aaauacaaca auaccaacua     1320

aacaaaccca aacauuuaca acuuacagug acaaucaacc aggagugcuc auacaaguuu     1380

acgaaggaga acgagcaaug acaaaagaca acaaucuauu aggaaaauuu gaacuaaccg     1440

gaauaccacc agcaccuaga ggcgugccac aaauagaagu cacauuugac auagaugcaa     1500

auggaauacu aaacgucagc gcagucgaua aaucaacagg aaaagaaaac aaaauaacca     1560

uaacaaacga caaaggacgc cugagcaaag aagauaucga acgaauggua caagaagcag     1620

aaaaauauaa agcggaggac gaaaaacaac gagacaaagu aagcaguaaa aacagcuuag     1680

aaucauaugc auuuaauaug aaagcaacug uagaagacga aaaauuacaa ggaaaaauaa     1740

acgaugaaga uaaacagaaa auacuagaca aauguaacga gauaauaaau uggcuggaca     1800

aaaaucaaac ggcagaaaaa gaagaauuug aacaucaaca aaaagagcuu gaaaaaguuu     1860

guaauccaau aauaacaaaa cuauaucaaa gugcaggagg aaugccagga ggaaugcccg     1920

gaggauuccc uggaggaggc gcacccccaa guggaggagc caguucaggc ccaacaauag     1980

aagaaguaga uuagggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  3207
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt6)

<400>  3207
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauau       60

cagcaagcag agcagcagca gcaagacuug ugggagcagc agcaucaaga ggaccuacag      120

cagcaaggca ucaagauucg uggaaugggu uaagccauga ggcguuuaga cuugugucua      180

ggagagauua cgccagcgaa gcaauuaaag gugcgguugu aggaauagau cuaggaacga      240

caaacucaug uguagcaguc auggaaggaa aacaagcaaa agugcuagaa aaugcagaag      300

gcgcaagaac aacaccauca guaguugcau uuacagcaga uggagaaagg uuaguuggua      360

ugccagcaaa aagacaagca guaacaaauc cgaacaauac auuuuacgcu acaaaaaggu      420

uaauaggaag aagauacgau gacccagaag ugcaaaaaga uauuaaaaau guaccuuuua      480

aaauagucag agcaucuaau ggugaugcau ggguagaggc ccacggaaaa cucuacucuc      540

caagucaaau aggagccuuc guauuaauga agaugaaaga aacagcugaa aauuauuuag      600

gacacacagc gaaaaaugca guaauaacgg uaccagcaua cuucaacgac agucaaagac      660

aggcaacaaa agacgcagga caaauaagug gauuaaacgu auuaagagua auaaaugaac      720

cuacagcagc agcauuagca uauggccuag auaaaucaga agacaaagua auagcgguau      780

augauuuagg cggaggaaca uuugacauuu caauauuaga gauacaaaaa gguguauuug      840

aaguuaaaag uacaaauggu gacacauuuu ugggaggaga agauuucgau caagcacuac      900

uucgacauau aguuaaagag uuuaaaagag aaacaggggu agaucucacu aaagauaaua      960

uggcauugca aaggguaagg gaagcagcug aaaaagcaaa gugcgagcua agcucaucug     1020

uacaaacgga uauuaaucua ccauauuuaa caauggacag cucaggucca aaacaucuca     1080

auaugaaauu aacaagagcu caauucgaag gaauaguaac ggacuuaaua agaagaacua     1140

uagcaccaug ucaaaaagcu augcaggaug cggaagugag caagagugac auaggagaag     1200

uuaucuuggu agguggaaug acaagaaugc caaaaguuca acagacagua caagaucuau     1260

ucgggagagc uccuaguaaa gcuguuaauc cagacgaagc cguagccaua ggagcagcaa     1320

uacaaggagg aguauuagca ggagauguaa cugauguacu acuauuagau guaacaccgu     1380

ugagccuugg aauagaaacu uuaggaggag uguucacuaa auuaaucaau agaaauacaa     1440

cgauaccuac gaagaaauca caaguauuca guacagcagc cgaugggcaa acacaaguag     1500

aaauaaaagu cugccaagga gaaagagaga uggcaggaga uaauaaauug uuagggcaau     1560

uuacauuaau agguauaccu ccagcaccga gaggaguacc ucagauagaa guuacauucg     1620

auauagaugc aaaugguaua guucauguau cagcaaaaga caaaggaacu ggaagagaac     1680

aacaaauagu gauacaaagc aguggaggac uaaguaaaga ugauauagaa aacaugguua     1740

aaaacgcgga aaaauaugca gaagaagaua gaagaaagaa agagagagua gaagcaguua     1800

acauggcuga aggaauaaua caugacacug aaacaaaaau ggaagaauuu aaagaucagc     1860

uaccagcaga ugaauguaau aaacuaaaag aggaaauaag uaaaaugaga gaauuguuag     1920

cuagaaaaga cagugagacu ggagaaaaua uuagacaagc agcaagcuca uuacaacaag     1980

caagccucaa auuauuugag auggcauaua agaaaauggc aucagaaagg gaaggauccg     2040

gaucaagcgg aacgggagaa caaaaagaag aucaaaaaga agaaaaacaa uagggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  3208
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt6)

<400>  3208
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

acaaagaagc aggcggaagu gaugggccaa gagaaacagc accaacauca gcauacaguu      120

caccagcaag aagccuagga gacacaggaa uaaccccauu aaguccaucg cacauuguaa      180

acgacacaga cuccaacgua agcgaacaac aaaguuuccu aguaguagua gcuguagauu      240

uuggaaccac aucaucagga uacgcauacu cauuuacaaa agaaccugaa uguauacaug      300

ucaugagaag augggaaggc ggagauccug gaguaaguaa ucaaaaaacu ccaacaacaa      360

uacuucucac accagaacga aaauuccacu cauuuggaua ugcagccaga gacuuuuacc      420

acgauuuaga uccaaaugaa gcaaaacaau gguuauaccu agaaaaauuc aaaaugaaac      480

uucauaccac uggagauuua acaauggaca cagaccuaac agcagccaau ggaaaaaaag      540

uaaaagcacu agagauauuu gcauacgcac uacaauacuu uaaagaacaa gcacuaaaag      600

aauuaagcga ccaagcaggu uccgaauuug aaaauucaga cguaagaugg guaauaacag      660

uccccgcaau auggaaacaa cccgccaagc aauuuaugag acaggcagca uaccaagcgg      720

gacuagccuc cccagaaaac ucagaacaac uaauuauagc acuugaacca gaggcagcgu      780

caauauauug uagaaaacua cgauuacauc aaaugauaga auuaaguuca aaagcagcag      840

uaaauggaua cucaggauca gauacagugg gagcaggauu uacacaagcu aaagaacaua      900

uuagaagaaa cagacaaagc agaacauuuc uuguagaaaa cgucauagga gaaauauggu      960

ccgaacuaga agaaggagau aaauauguag uaguugacag cggaggagga acaguagauc     1020

uaacugucca ucaaaucaga cuacccgaag ggcacuuaaa ggaacuauac aaagcaacgg     1080

gaggcccaua cggcucauua ggaguugacu acgaauucga aaaauuauua uacaaaauau     1140

ucggagaaga uuuuauagaa caauuuaaaa ucaaaaggcc ugcagcaugg guagauuuaa     1200

ugauagcauu ugaaagcaga aaaagagccg cagcacccga uagaacaaac ccacuaaaua     1260

uaacacuacc guucucauuu auagauuacu auaaaaaauu uagaggacau ucgguagaac     1320

augcacuaag aaaaagcaac guugacuuug ucaaauggag cagucaagga auguuacgga     1380

ugagcccaga ugcaaugaau gcacuauuca aaccaacaau agauaguauc auagaacauu     1440

uaagagauuu auuucaaaaa ccagaaguca guacaguaaa auuccuauuc uuaguaggcg     1500

gauucgcaga agcaccccua uuacaacaag ccguacaagc agcauucgga gaucaaugua     1560

gaauaauaau cccacaagau gucggacuca caauacucaa aggagcaguu cuauucggac     1620

ucgacccagc aguaauuaaa guaagaagau caccacuuac cuaugguguu gguguauuaa     1680

auagauaugu agaaggaaaa cacccuccag aaaaauuauu aguaaaagau ggaacaagau     1740

ggugcacuga cguauuugau aaauuuauuu cggcagacca aucaguagcu cuaggugaac     1800

uuguaaaacg auccuauaca ccugcaaaac caucacaacu agucauagua auaaauauau     1860

acuccucaga acacgauaau gucucauuua ucacugaccc aggaguaaaa aaauguggca     1920

cauuaagauu agauuugaca gguacaagug guacugcagu acccgcacga agagaaaucc     1980

agacauuaau gcaauuuggc gacacagaaa ucaaagccac agcaauagac auagccacau     2040

cuaaaucagu aaaaguagga auagacuucu uaaauuauua aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  3209
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt6)

<400>  3209
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcuug       60

caguuccaga aaugggacua caaggacuau auauaggcag uucaccagaa cgaaguccgg      120

uacccagucc accgggauca ccaaggacac aagaaaguug cggaauagca ccucuaacac      180

cuagccaauc accuaaaccu gaagugagag caccacaaca agcgaguuuc ucgguuguag      240

uagcaauaga uuucggaaca acaucaagug guuaugcauu uucauuugcu ucagauccag      300

aagcuauaca uaugaugcga aaaugggaag gaggcgaucc uggcguagca caucagaaaa      360

ccccuacuug ucuauugcua acaccagaag gagcauuuca uaguuuugga uauaccgcuc      420

gagauuacua ucaugacuua gauccagaag aagcaaggga uugguuauac uuugaaaaau      480

uuaaaaugaa aauacauagu gccacggauc uaacauuaaa aacacaauua gaagcaguaa      540

auggaaaaac aaugccagca uuagaaguau uugcacacgc auugagauuc uuucgcgaac      600

augccuuaca agaacuacgc gaacaauccc cuuccuuacc agaaaaggau acuguacgau      660

ggguauuaac aguccccgcu auauggaaac aaccggcuaa acaauuuaug agagaagcag      720

cauauuuggc uggccuaguc agccgggaaa acgcugaaca auuacuaaua gcauuagaac      780

cagaagcugc aagcguauac uguagaaaac uaagacuuca ucaauuacua gaucuaagcg      840

gaagggcacc uggaggaggg cgauuaggag aaagaagauc uauagauuca ucauuuagac      900

aagcuagaga acaauuaaga agaucacguc acucaagaac auuucuaguu gaaucaggug      960

uaggcgaacu uugggcagaa augcaagcag gagacagaua uguaguggcu gacugcggag     1020

gggguacagu ugaccuaaca guacaucaau uagaacaacc acacggaaca cuaaaagaau     1080

uauauaaggc uucaggagga ccauacgggg caguaggagu ugaucuagcu uuugaacaac     1140

uacuuugucg aauauucggu gaagauuuua uagcaacauu uaaaaggcaa agaccugcug     1200

cauggguaga ucuaacuaua gcauucgagg caagaaaacg aacagcagga ccacauagag     1260

cuggugcuuu aaacauuuca uuaccauuuu cauucauaga uuuuuacaga aaacaaagag     1320

gacauaaugu agaaacagca uuaagaagaa guucaguaaa uuuuguaaaa uggucuaguc     1380

aaggaaugcu aagaauguca ugcgaagcua ugaacgaacu auuucaaccc acaguauccg     1440

guauaauaca acauauagaa gcacuauuag cuagaccuga aguacaagga guaaaauuau     1500

uauuuuuagu aggaggauuc gcagaaucag cuguguuaca acaugcugug caagcagcgu     1560

ugggcgcuag aggucuaaga guaguaguuc cucacgaugu aggacuaaca auacuaaaag     1620

gagcaguauu auucggccaa gcgccuggag uaguucgagu aagaagaucu ccauuaacau     1680

augguguggg aguauuaaau agauucgugc cagguagaca uccaccagag aagcuauuag     1740

uaagagaugg caggaggugg uguacugaug ucuucgaaag guuuguugca gccgaacaaa     1800

gcguugcacu aggagaagaa guuagaagau cauacugucc agcacggcca ggacaaagaa     1860

gagugcuaau uaacuuauau uguugcgcag cagaagaugc aagauuuauu acagacccag     1920

guguaagaaa guguggagcc cucaguuuag aacuugaacc agcugauugc ggccaagaua     1980

cagcaggcgc acccccaggc agacgagaaa uaagagcggc aaugcaauuu ggagauacag     2040

aaauaaaagu uacagcugua gauguaagca caaacagaag uguuagagca ucaauagacu     2100

uucuaaguaa cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  3210
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt6)

<400>  3210
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcua       60

gagaaaugac aauacucggc ucugcaguau uaaccuuacu auuagcagga uauuuagcac      120

aacaauaccu ucccuuacca acaccaaaag uaauagguau agaucucggu acaacauauu      180

guuccgucgg aguuuucuuu ccaggaaccg gaaaaguuaa aguuauacca gacgaaaaug      240

gacacauauc cauaccaagu augguaaguu uuaccgacaa cgauguauau gucgguuacg      300

aaagcguaga auuagcagau aguaauccac aaaacacaau auaugacgca aaaagauuca      360

uaggaaaaau cuucaccgca gaagaacugg aagcagaaau aggaagauau ccauucaaag      420

uacuaaauaa aaauggaaug guagaauucu caguaacuuc caaugaaaca auaacaguau      480

caccagaaua ugucggcuca agauuauuau uaaaauuaaa agaaauggca gaagcauacu      540

uaggaaugcc aguagcaaac gcaguaaucu caguaccagc cgaauucgau uuaaaacaaa      600

gaaauuccac uauagaagca gcaaaucuag caggucuuaa aauauuaaga guaauaaaug      660

aacccacagc agcagcaaug gcauauggac uacacaaagc agauguuuuu cacguacuag      720

ugauagauuu aggaggcggc acauuagacg uaagucuacu caauaaacaa ggcgguaugu      780

uucuaacaag agccaugagu ggaaacaaca aauuaggagg acaagacuuu aaccaaagac      840

uacuacaaua uuuauacaaa caaauuuacc aaacauaugg auucguccca ucaagaaaag      900

aggaaaucca cagacuaagg caagcaguag agauggucaa acuaaacuua acauuacauc      960

aaucagcaca acuaucaguc uuauuaacag uagaagagca agauagaaaa gaaccucacu     1020

ccagugacac agaacucccu aaagauaaac uaucaucagc agaugaccac cgagucaaca     1080

guggauucgg aagaggccua agugacaaaa aaagcggaga aucacaagua uuauuugaaa     1140

cugaaauuag cagaaaacua uuugauacau uaaaugaaga ccuauuucaa aaaauacuag     1200

uaccaauaca acaaguacuc aaagaaggac auuuagaaaa aacagaaaua gacgaaguag     1260

uacuaguagg aggaagcaca cgaauuccua gaauaagaca aguaauacaa gaauuuuucg     1320

gcaaagaccc uaauacauca guagacccag aucuagccgu cguaacagga guagcaauac     1380

aggcaggaau agauggagga agcuggccac uucaagucag ugccuuagaa aucccaaaca     1440

aacauuuaca aaaaaccaau uucaacuaag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3211
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt6)

<400>  3211
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

caauaggagu acaccuagga uguacaucag cauguguagc cguauauaaa gaugguagag      120

caggaguugu ggccaaugau gccggagaua gaguaacucc ugcaguaguu gcauacagcg      180

aaaaugaaga gauaguugga cuagcugcaa aacaaagcag aauaagaaau auaaguaaua      240

caguaaugaa agucaaacaa auauuaggaa gaucaaguuc agacccucaa gcucaaaaau      300

acauugcuga aagcaaaugu cuaguaauag agaaaaaugg aaaacuaaga uaugaaauug      360

auacggguga agaaacuaaa uucguaaacc cagaagaugu agcaagacua auauuuagua      420

aaaugaaaga aacagcucau ucaguauuag gaucagacgc aaaugacgua guaauaacug      480

uaccauucga uuuuggagaa aaacaaaaga acgcuuuagg agaagcggcu agagcagcag      540

guuuuaaugu auuaagacua auacaugaac cauccgcugc acuauuagca uacggaauag      600

gacaagauag uccaacaggu aaaucaaaua uccuaguauu caaauuagga ggaacaucau      660

uaucguuauc aguaauggaa guaaauagug ggauauauag aguauugagc acaaauacag      720

augauaauau aggcggagca cauuuuacag aaacucuagc acaauaucua gcaagugaau      780

uucaaagaag uuuuaaacau gauguucgag gaaaugcaag agcaaugaug aaauuaacaa      840

auucagcgga aguagcaaaa cacucauuaa gcacguuagg uagugcaaau uguuucuuag      900

auaguuuaua ugaaggacaa gauuuugauu guaauguauc acgagcccga uuugaauuau      960

uauguagccc ucuauuuaau aaauguauag aagcaauaag gggauuacuc gaucaaaaug     1020

gauucacagc ugaugauaua aauaaaguag uauuaugugg agguucaagu agaauaccua     1080

aauuacaaca acuaauaaaa gacuuauuuc cagcaguaga acugcuaaau aguauaccgc     1140

cagacgaagu aauaccaaua ggagcagcaa uugaagccgg aauacuaauu ggaaaagaaa     1200

aucuauuagu agaagacagc cuuaugauag aauguagugc aagagacaua cucgucaaag     1260

gcguagauga auccggagca aguagauuca cuguauuauu cccaucagga acgccacuac     1320

cagcaagaag acaacauaca cuacaagcac caggaagcau aucaagugua ugucuagaac     1380

uauaugaauc agacgggaaa aauagcgcaa aagaagaaac aaaauuugca caaguaguau     1440

uacaagauuu agacaagaaa gaaaauggau uaagagauau auuagcagua uuaacuauga     1500

aacgagacgg aagucuacau guaacaugua cagaucaaga gacaggaaaa ugugaagcga     1560

uaucaauaga aauugcuagc uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  3212
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt6)

<400>  3212
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucag       60

uaguaggacu ugauguagga ucacaaucau guuauauagc aguagcacga gcaggaggua      120

uagaaacaau agcaaaugaa uucagcgaua gauguacacc uucagucaua ucuuucggau      180

caaagaaucg aaccauuggc guagccgcaa aaaaccaaca aaucacgcac gcuaacaaua      240

caguaucaaa cuuuaaaaga uuucacgguc gagcguuuaa ugaccccuuc auucaaaaag      300

aaaaagaaaa cuuaagcuau gaccuuguac cacuuaaaaa uggaggagua ggcauuaaag      360

uaauguacau gggagaagaa caccuauuua guguagaaca aaucaccgcg augcuacuaa      420

caaaacuaaa agaaacagca gagaauagcc uaaaaaaacc aguuacugac ugcguaauaa      480

guguaccauc uuucuuuacc gacgcagaaa gacgguccgu ucuagaugca gcccaaauag      540

uaggauuaaa cugucucaga cuaaugaaug auaugacugc aguggcucua aauuauggaa      600

uauauaaaca agacuugcca ucacuagaug aaaaaccaag aaucguaguc uucgucgaua      660

ugggccauag cgcauuucaa guuucagcau gugcuuucaa caaaggaaaa cugaaaguuc      720

uaggaacggc auucgaucca uuucuagggg gaaaaaauuu ugacgaaaaa uuaguagaac      780

acuuuugcgc cgaauucaaa acaaaauaca aacuagacgc aaaaaguaaa auaagagcau      840

uauugagauu auaccaagaa ugcgaaaaac uaaaaaaauu aaugagcucc aacucaacag      900

acuugccauu aaacauagaa ugcuucauga augauaaaga cguauccggu aaaaugaaua      960

gaucccaguu cgaggaacua ugugccgaac uacuucaaaa aauagaagua ccauuauacu     1020

cacuauuaga acaaacucac cuaaaagucg aagacguaag ugcaguagaa auuguaggug     1080

gagcaacaag aauaccggcu guaaaagaaa gaauagcaaa auucuuugga aaagauauau     1140

caacaacauu aaacgccgau gaagccguag cuagagggug cgcacuucaa ugcgccauau     1200

uaucaccagc guuuaaaguc agagaauuca guguuaccga ugcaguacca uucccaauaa     1260

guuuaauaug gaaccaugac ucagaagaca ccgaaggagu ucaugaagua uuuagccgaa     1320

accacgccgc accauuuagu aaaguauuaa cauuucuaag acguggucca uuugagcuug     1380

aagcauuuua uucugaucca caaggaguac cauacccaga agcaaaaaua ggcagauuug     1440

ucguacaaaa cguaucggca caaaaagaug gagaaaaauc acgagucaaa guaaagguga     1500

gaguaaacac acauggaaua uucacaauaa guacagccag caugguggaa aaaguuccaa     1560

cagaagaaaa cgaaaugagc agcgaagcag auauggaaug ucuaaaccaa agaccgccag     1620

aaaacccaga cacagauaag aauguccaac aagacaacuc ugaagcaggc acucaaccac     1680

aaguucaaac agaugcacaa caaacuucac aaucaccacc gucuccagaa uuaaccagug     1740

aagaaaacaa aauacccgac gcagauaaag caaacgaaaa aaaaguagac caaccaccag     1800

aagcaaagaa accaaaaauu aaagucguga acguagaauu accaauagaa gcaaaucuag     1860

uauggcaauu aggcaaagac cuauuaaaua uguauaucga gaccgaaggu aaaaugauaa     1920

ugcaagacaa auuagagaaa gaacgaaaug augcaaaaaa ugcaguagaa gaauauguau     1980

augaauuuag agauaaacua uguggaccgu acgaaaaauu uauaugugaa caagaccauc     2040

aaaauuuucu acgacuucua acugagacag aagacuggcu auacgaagaa ggagaagauc     2100

aagcaaaaca agcguaugua gacaaacuag aagaauuaau gaagauaggu acaccaguaa     2160

aaguacgauu ccaagaagca gaagagagac caaaaauguu ugaagaacug ggucaaagau     2220

uacaacacua ugcaaaaauc gccgcagacu uucgaaacaa agacgaaaag uauaaucaua     2280

uagaugaauc agaaaugaaa aaagucgaaa aaagugucaa cgaagugaug gaguggauga     2340

auaacguuau gaaugcacaa gccaaaaaaa gccuagauca agauccugua guaagagcac     2400

aagagaucaa aaccaaaaua aaagaacuaa auaacaccug cgagccagug guuacccagc     2460

caaaaccaaa aauagaaagu cccaaauuag agagaacccc caauggacca aauauagaua     2520

aaaaagaaga agaccuagag gauaaaaaua acuucggagc cgaaccacca caccaaaaug     2580

gggaauguua ccccaacgaa aaaaauagug uaaacaugga uuuagacuaa ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  3213
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt6)

<400>  3213
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcug       60

auaaagucag acgacaacgg ccaagaagaa ggguaugcug ggcacuggua gcaguucugc      120

uagccgauuu auuagcguua ucagauaccc uagcuguaau gagcguagac uuaggcagug      180

aaaguaugaa aguggcaaua guaaaaccag gaguacccau ggagauuguu uuaaauaaag      240

aaucaagaag aaagacgcca guaauaguaa cgcuaaaaga gaacgaaaga uucuuuggag      300

acucagcagc aaguauggca auuaaaaacc caaaagcaac ccugagauac uuucaacauc      360

uguugggcaa acaagcagac aacccacaug uagcgcuaua ccaagcgagg uuuccugaac      420

acgaacuaac auucgaccca caaagacaaa caguacacuu ccaaauaucu ucacaacucc      480

aauuuucacc ugaggaagua cuuggaaugg ucuuaaacua cagucgaagu uuggcggaag      540

auuuugccga acaaccuaua aaagaugcag uaauaacagu accuguauuc uuuaaucaag      600

ccgagaggag agcuguauua caagcugcaa gaauggcugg acuuaaagua cuacaacuca      660

uaaaugacaa uacagcuacu gcacuaucau augguguuuu uagaagaaaa gacauaaaca      720

caacugcaca aaauaucaug uuuuacgaua ugggaagcgg aagcacaguc ugcacuauag      780

ucaccuauca gauggugaaa acaaaagaag caggaaugca gccucaauua caaauaagag      840

gaguagguuu ugacagaacg cuggguggau uagaaaugga acugagauua agagaacgau      900

uggcaggacu auucaaugag caacgaaagg gucagagagc uaaagacguu agagaaaauc      960

cucgcgcaau ggcuaaacuu uuacgcgaag caaauagauu aaagacagua cuuagugcaa     1020

acgcagacca uauggcucaa auagaaggac uaauggauga cguagacuuu aaagcaaaag     1080

uaacacgagu agaguucgaa gaacuaugug cagaucucuu ugaaagagua ccugguccag     1140

uacaacaagc ucuacaaagu gcugaaaugu cuuuagacga aauugaacaa guaauauugg     1200

ucggcggagc aacacgaguu ccuagaguac aagaaguauu gcuuaaggca guaggaaaag     1260

aagaacuagg gaaaaauaua aacgcugacg aagcagcagc aaugggagcc guuuaccaag     1320

cggcagcacu aagcaaggcu uuuaaaguua aaccauuugu aguaagagau gcaguuguau     1380

auccaauuuu aguagaauuu acucgagaag uagaagaaga accagggaua cacucacuaa     1440

aacacaacaa aagaguacuc uuuagcagga ugggaccgua uccacaacgu aaagucauaa     1500

cauuuaacag auauucucau gauuuuaauu uccauauaaa cuacggagac uuaggcuuuu     1560

uagguccaga agaucuaagg guauuugguu cacaaaaucu cacaacgguu aaacuaaaag     1620

ggguaggaga uaguuucaag aaauacccag acuaugaauc uaaaggaaua aaagcacauu     1680

uuaaucuaga ugaaaguggg guauugaguc uagaccgagu cgagagcgua uucgaaacuc     1740

ugguugaaga uagugccgaa gaggaaucaa ccuugacuaa acuagguaau acgauaagca     1800

gcuuauucgg agguggcaca acaccagaug caaaagaaaa uggaacagac acaguacagg     1860

aagaagaaga aagcccggca gagggcucaa aagaugaacc uggggaacaa guagaguuaa     1920

aagaagaagc agaagcacca guggaagacg guucgcaacc accuccccca gagccaaaag     1980

gugaugcaac accagaaggc gaaaaagcaa cagaaaaaga aaauggggau aaaucagaag     2040

cacaaaagcc aagugaaaaa gcagaagcug gaccagaagg aguugcuccu gcaccagaag     2100

gagaaaagaa acaaaaaccc gcacgcaaaa gaagaauggu agaggaaaua ggugucgagc     2160

uaguaguauu agaucuacca gaucucccag aagacaaauu ggcacaaagu guacaaaaac     2220

ugcaggacuu aaccuuaaga gacuuagaaa aacaagaaag ggaaaaagcu gcaaauucuu     2280

uggaagcauu cauauucgaa acacaggaca aauuauauca acccgaauau caggaaguau     2340

ccacagaaga acaaagagaa gaaauaucag gaaaacucuc agcagcauca acgugguugg     2400

aagaugaagg aguaggugca acaacaguaa uguuaaaaga aaaauuagca gaacuaagga     2460

aacugugcca aggauuauuu uucagagucg aagaaagaaa gaaauggcca gaacgguuau     2520

cugcauuaga uaauuuacua aaccacucua guauguuucu aaaaggggcc agauuaauac     2580

cagaaaugga ucaaauuuuu acugaaguag aaaugacaac acuagaaaaa guaaucaacg     2640

aaacaugggc auggaaaaau gcaacuuuag cagaacaagc aaaauuaccg gcaacagaaa     2700

aaccagucuu acuaucaaaa gacauagaag cgaaaaugau ggcauuagac agagaagucc     2760

aauaccuacu aaacaaagca aaguucacaa aacccagacc gcggccaaaa gauaaaaacg     2820

gaacccgagc cgagccacca cuaaaugcaa gcgcaaguga ucaaggggag aagguaauac     2880

cgccugcagg acaaacagaa gacgcagaac caaucuccga accagaaaaa guagaaacag     2940

gaucggaacc uggagauaca gaaccccuag aauuaggagg accuggagcu gagccagaac     3000

aaaaagaaca aaguacagga caaaaacgac cucuuaaaaa ugacgaacua uaaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3214
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt6)

<400>  3214
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

aagaaaccca aacacaagac caacccaugg aagaagagga aguagaaaca uucgcuuucc      120

aagcagaaau ugcacaauua augagucuaa uuauaaacac auucuacuca aacaaagaaa      180

uauuuuuacg cgaacuaaua agcaacucaa gcgaugcauu agauaaaauu agauaugaau      240

cguuaacaga uccaagcaaa uuagacucag gaaaagaauu acacauaaau cuuaucccaa      300

acaaacaaga uagaacacuu accauagucg acaccggaau aggaaugaca aaagcugacc      360

uaauaaacaa uuuagguaca auagcaaaau cggguaccaa agcauucaug gaagcacuac      420

aagcaggugc cgacaucucg augauaggac aauuuggagu aggauucuac agcgcauacc      480

uaguagcaga gaaaguaaca guuauaacaa agcacaacga cgacgaacaa uacgccuggg      540

aaucaagugc aggaggauca uucacaguaa gaacagacac aggugaacca augggcagag      600

guacgaaagu aauacuucau cuuaaagaag accaaacaga auaccuagag gaaagaagaa      660

ucaaagaaau aguaaaaaaa cacucacaau ucauaggaua uccaauaaca cucuuuguag      720

agaaagaaag agacaaagaa gucagugacg augaagcaga ggaaaaagaa gauaaagaag      780

aagaaaaaga aaaagaagaa aaagaaagug aagacaaacc agaaauagaa gacguaggau      840

cggaugagga ggaagaaaaa aaagauggag acaaaaaaaa aaagaaaaaa auaaaagaaa      900

aauacauaga ucaagaagaa cugaacaaaa ccaaaccaau auggacaagg aaccccgacg      960

acaucacaaa cgaagaauac ggagaauuuu acaaaucacu uacaaaugac ugggaagacc     1020

accucgccgu caaacacuuu agcguagaag gucaauuaga auucagagcc cuacuguuug     1080

uaccuagaag agcaccauuc gauuuguuug agaauagaaa aaaaaaaaau aauaucaaac     1140

uauacguaag aagaguauuu auaauggaca auugcgaaga auuaauacca gaauaucuaa     1200

auuuuaucag gggaguaguc gacagcgaag auuuaccauu aaacauaucg cgagagaugu     1260

uacaacaauc aaaaauucug aaaguaauaa gaaaaaaucu agucaaaaaa ugucuagaac     1320

uauucacaga acuagcagaa gacaaagaaa acuacaaaaa auucuaugaa caauucucaa     1380

aaaauauaaa auugggcaua cacgaagacu cucagaauag aaaaaaacua ucagaauuac     1440

uaagauauua uacgucagcu aguggagacg agaugguauc ccuaaaagac uacugcacaa     1500

ggaugaaaga aaaucaaaaa cauauauacu acauaacugg agaaaccaag gaccaagucg     1560

caaacucagc auucguagaa agauuacgaa agcauggacu ggaaguaaua uacaugauag     1620

aacccauaga ugaauauugc guacaacaau uaaaagaauu cgaaggaaaa acuuuaguaa     1680

gcguaacgaa agaaggacua gaauuacccg aagaugaaga agagaaaaaa aaacaagaag     1740

agaaaaaaac caaauucgaa aacuuaugua aaauaaugaa agacauauua gaaaaaaaag     1800

uagaaaaagu uguaguauca aacagacuag uaacaagccc auguugcaua guaacaagua     1860

ccuacgggug gacggcaaac auggaaagaa uaaugaaagc ccaagcuuua cgagacaaua     1920

guacgauggg auacauggca gccaaaaagc auuuagaaau aaacccagac cacagcauaa     1980

ucgaaacacu uagacaaaaa gccgaagcug auaaaaacga caaauccgug aaagaccucg     2040

ucaucuuacu uuaugaaaca gcauuauuaa guaguggauu cucccuagaa gacccgcaaa     2100

cacacgcuaa ucgaauauac cgaaugauua agcucggauu aggaauagac gaagaugacc     2160

caacagcgga ugauacaagc gcagcaguaa cugaagagau gccaccauua gaaggagaug     2220

augauacguc aaggauggaa gaagucgacu aaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  3215
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt6)

<400>  3215
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

caagcaaacu agacagcgga aaaggacuac acauaaacuu aguaccaaac aaacaaaacc      120

aaacacuaac aauaguagac acaagaauag gaaugacaaa aacagacuua auaaacaacc      180

uaggaacagu aacaaaauca ggaacaaaag cauucaugga agcacuacaa gcagacgcag      240

acauaucaau gauaggacac uucggaguag gauucuacuc agcauaccua guagcaaaaa      300

aaguaacagu aauaucaaaa cacaacaacg acgaacaaua cacaugggaa ucaucagcag      360

gaggaucauu cacaguaaga acagacgaau aaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  3216
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt6)

<400>  3216
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aagaagugca ucauggcgaa gaggagguag aaacauucgc uuuucaagcu gaaauagcuc      120

agcuaaugag ccuaauaaua aacacuuuuu acagcaacaa agaaauauuu cuccgcgagu      180

uaauaucaaa cgcuucagau gcacuugaua aaauaagaua cgagagccua acagacccua      240

guaaacuaga uagcgguaaa gaacuaaaaa uagacauaau acccaacccg caagaaagaa      300

cacuuacacu ugucgauacu ggaauaggaa ugacaaaagc agaucuaaua aauaacuuag      360

gaacaauagc aaaaucaggg acgaaagcgu uuauggaagc auuacaagca ggagcagaua      420

uuaguaugau aggacaauuu ggaguaggau ucuacagugc uuaucuugua gcagaaaaag      480

uaguaguaau aacaaaacac aaugacgacg aacaauaugc uugggaaucu ucagccggag      540

ggucauucac gguuagagca gaccacggag aaccaauagg aagaggcacu aagguaauac      600

uacauuuaaa ggaagaucag acagaauacc uugaagaacg aagaguaaaa gaaguaguaa      660

aaaaacauuc acaauuuaua ggauacccca uaacauuaua ccuggaaaaa gaaagagaaa      720

aagaaauauc ugacgacgaa gccgaagaag aaaaaggaga aaaagaagaa gaagacaaag      780

augaugaaga aaaaccgaaa aucgaagacg uaggaucaga cgaagaagac gacucaggaa      840

aagacaaaaa aaaaaaaaca aaaaaaauaa aagaaaaaua cauagaucaa gaagaauuga      900

acaaaacaaa accaauaugg acaagaaauc cagaugauau aacacaagaa gaauauggag      960

aauucuacaa aagucuuaca aaugacuggg aagaccaucu agcagucaaa cauuuuucag     1020

uagaaggaca acuagaauuc agagcguuau uauuuauacc aagaagagcg ccauucgacc     1080

uauuugaaaa caaaaaaaaa aaaaacaaua uaaaacuaua cguaagaaga gucuucauaa     1140

uggacucgug cgaugaauua auaccagaau acuuaaauuu cauaagagga guagucgauu     1200

ccgaagacuu accacuaaau auaucucgag aaauguuaca acaauccaaa auacuaaaag     1260

ugauaagaaa aaauaucgua aaaaaauguc uugaacuauu uucggaacuu gcggaagaca     1320

aggaaaauua uaaaaaauuu uaugaagcgu ucaguaaaaa cuuaaagcua ggcauacaug     1380

aagacuccac aaauagaaga agacuaagcg aacuauuaag auaccauaca ucacaaucag     1440

gagacgaaau gacaucucua agugaauaug ugagcaggau gaaagaaacc caaaaaucaa     1500

uauacuacau aacaggagaa ucgaaagaac agguagcaaa uucagcauuc gucgaacgug     1560

uacgcaaaag aggauuugaa guaguauaca ugacugagcc aauagacgaa uauuguguac     1620

aacaacuaaa agaauucgac ggaaaaaguc uagucagugu aacaaaagaa ggacuagaac     1680

uaccagaaga ugaagaagaa aaaaaaaaaa uggaagaaag caaagcaaag uucgaaaauu     1740

uaugcaaauu aaugaaagaa auacuagaua aaaaagucga aaaaguuaca auuucaaaua     1800

gacuagucuc aucaccaugc ugcauaguca caagcacaua cggauggacc gccaauaugg     1860

aaagaauaau gaaggcacaa gcauuaagag auaacagcac gaugggauac augauggcaa     1920

aaaaacaucu ugaaauaaau ccagaccacc caauagucga aacacuaaga cagaaagcag     1980

aagcagauaa aaacgacaaa gcuguaaaag accucguggu ccugcucuuc gaaacagcau     2040

uacugaguuc aggauucucg cuggaagacc cacagacuca uucaaauaga auuuacagaa     2100

ugauaaaacu aggauuagga aucgaugaag acgaaguggc agcagaagaa ccaaacgccg     2160

cggucccaga cgaaauaccu ccauuagaag gagacgagga ugcaagccga auggaagaag     2220

uagauuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  3217
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt6)

<400>  3217
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcgag       60

cuuuaugggu acuaggcuua uguugcguau uacuuacauu cggaucagua cgugcagacg      120

augaaguaga uguagauggu acaguagaag aagauuuagg caaaucaaga gaaggaagua      180

ggacagacga ugagguagua caaagagaag aagaagcaau ucaacuagac ggacuuaacg      240

caucucaaau aagagaauua cgagaaaaau cagaaaaauu ugcauuccag gcagaaguaa      300

auagaaugau gaaacuaauc auaaauaguc ucuauaaaaa caaagaaaua uucuuacgag      360

aacuaauauc aaaugcaagu gaugcuuuag acaaaauacg acuuaucagu cuaacagaug      420

aaaaugcacu caguggcaau gaagaacuaa caguuaaaau aaaaugcgau aaagagaaaa      480

auuuacuaca uguuacagac accgguguag gaaugacaag agaagaauua guuaaaaauu      540

uaggaacaau agcaaaaagu ggaacaagug aauuucuaaa uaaaaugacu gaagcucagg      600

aagauggaca aagcacuuca gaacuaauug gacaauucgg aguaggauuc uacucagcau      660

uccuuguagc ugauaaagua aucguaacua gcaaacacaa uaacgacaca caacauauau      720

gggaaucaga uucaaacgaa uuuagcguaa uugcagaucc aagaggaaau acacuaggaa      780

gagggaccac aauaacauua guacuaaaag aggaagcaag cgacuacuua gaacucgaua      840

cgauuaaaaa uuuaguaaag aaauacucac aguuuauaaa uuucccaaua uacgucugga      900

guaguaaaac agaaacagua gaagaaccaa uggaggaaga agaagcagcc aaagaagaaa      960

aagaagaauc ggacgacgaa gcugcugucg aagaagaaga agaagaaaag aaaccaaaaa     1020

caaagaaagu agagaaaacu guuugggauu gggaauuaau gaacgauauc aaaccaauau     1080

ggcaaagacc cucaaaagaa gucgaagaag acgaauauaa agccuuuuac aagucauuuu     1140

ccaaagaauc ggaugaccca auggcauaua uucacuuuac agcagaggga gaagucacau     1200

uuaaaucuau acuuuuuguc ccaacaagug caccgagagg auuauuugau gaauacgguu     1260

caaagaaauc agacuauaua aaauuauaug uaagaagagu guucauaaca gacgacuuuc     1320

acgauaugau gccgaaauac uuaaacuuug uuaaaggagu cguugacagc gaugaccuac     1380

cacucaacgu aaguagagaa acacuacaac aacauaaacu auugaaaguu auaagaaaga     1440

aacucguaag aaaaacuuua gacaugauua agaaaauagc agacgacaaa uauaacgaua     1500

cauuuuggaa agaguucggu acaaauauaa aacuaggagu aauagaagac cacaguaaua     1560

gaacccgauu agccaaauua cucagguucc aaucaucgca ucacccaaca gacaucacga     1620

gcuuagauca auauguagaa agaaugaaag aaaaacaaga uaaaauauac uuuauggcgg     1680

gaucaucaag aaaagaagcc gaaucuucuc cauucguuga acgacuauua aagaaaggau     1740

augaaguaau auaccuaaca gaaccuguag augaauauug uauacaagca cuaccagaau     1800

uugauggcaa acgcuuccaa aauguagcaa aagaaggcgu uaaauuugau gaaagcgaaa     1860

agacaaaaga aaguagagaa gcgguugaaa aagaguucga accauuauua aauuggauga     1920

aagacaaagc acuaaaagau aaaauagaaa aagcuguagu aucucaaaga uuaaccgaau     1980

ccccgugcgc acucguagcc agucaauaug gcuggucagg uaacauggaa agaauaauga     2040

aagcucaagc auaucaaaca ggaaaagaua uaaguacgaa cuauuacgca ucucaaaaga     2100

aaacauucga aauaaaucca agacacccac ugauaagaga uauguuaagg cgaauaaaag     2160

aagaugaaga cgacaaaaca guucuagacu uagcugucgu acuauucgaa acagcaacau     2220

uaagaagcgg auacuuacua ccagacacaa aagcauaugg agauaggaua gaacggaugu     2280

uacgacuaag ucucaacaua gauccagaug ccaaaguuga agaagaacca gaagaggaac     2340

cagaagagac cgcagaagac acaacagaag acacagaaca ggacgaagac gaagaaaugg     2400

acguaggaac ugacgaagaa gaagaaacag caaaagaauc uacagcagaa aaagacgagc     2460

uguaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  3218
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt6)

<400>  3218
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

gagaauuaag agcucuuuua cuauggggua gacgacugag accauuauua agggcgccag      120

cccucgcagc aguaccagga ggaaaaccaa uacucugccc aagaagaaca accgcacaau      180

uaggcccaag aagaaaucca gcauggucau uacaagcugg aagacuauuu uccacccaaa      240

cagcagaaga uaaagaagaa cccuuacauu caauaauauc aagcacagaa ucaguccaag      300

gaucaacauc aaaacaugaa uuucaagcag aaacaaagaa acuauuagau auuguugcua      360

gaagccuuua uucugaaaaa gaaguauuua uaagagaacu aauuaguaac gcuagcgacg      420

ccuuagaaaa gcuaagacac aaguuaguaa gugauggaca agcauuacca gaaauggaaa      480

uacaccugca aaccaaugca gaaaaaggaa caauaaccau acaagauacc ggcauaggaa      540

ugacacaaga agaauuagua aguaaccuug gaacaauagc uagaagcgga ucaaaagcau      600

uccucgacgc acuacaaaac caagcagaag caucauccaa aauaauugga caauuuggcg      660

uaggauucua uagugccuuu augguagcag aucgugucga agucuauuca cgaucagcag      720

caccaggauc acuaggguau caaugguuau cagacggauc cgguguauuc gaaauugccg      780

aagccucggg cguaagaacg gguacuaaaa uaauaauaca uuuaaaauca gauugcaaag      840

aauucucuuc agaagcacga guccgagaug uaguaacgaa auauucaaac uuuguuaguu      900

uucccuuaua uuuaaauggu cguagaauga auaccuuaca agcaauaugg augauggauc      960

caaaagaugu uagagaaugg caacaugaag aauuuuauag auauguugcu caagcucaug     1020

acaaaccccg auauacuuua cacuacaaaa cagacgcacc auuaaauauc aggaguauau     1080

uuuaugugcc agauaugaaa cccucgaugu uugaugucag uagagaauua ggaagcagug     1140

uggcucuaua uucuagaaaa guacucauac aaaccaaagc aacggauaua uuaccaaaau     1200

ggcucagauu uauaagagga guuguugauu cagaagacau acccuuaaau cuuaguagag     1260

aacuacuuca agaaucagca uuaauaagaa aauuaagaga cguccuucaa caaagauuaa     1320

uuaaauucuu uauagaccaa ucaaaaaaag augcagaaaa auaugcaaaa uucuucgaag     1380

acuauggauu auuuaugaga gaaggaauag uaacagcaac agaacaagaa guaaaagagg     1440

auauagcaaa auuauuacgg uacgaaucau cagcauuacc aucaggacaa cuuacaucau     1500

uauccgaaua cgccagucga augagagcag gcacaagaaa cauauauuac cuaugugcac     1560

caaacagaca ucuagcagag cacucaccuu auuacgaagc aaugaaaaaa aaagauacag     1620

aaguucuauu uugcuuugaa caauuugacg agcuuaccuu acuccaucua agagaauuug     1680

acaaaaaaaa auuaauaagu guugaaacag acauaguagu ugaucauuau aaagaagaaa     1740

aauuugaaga ucgaagccca gcagcagaau gccuaucaga aaaagaaacc gaagaauuaa     1800

uggccuggau gcguaauguu cuaggaagca gaguuacaaa cguaaaagua acgcuaagau     1860

uagauacuca uccagccaug guaacugugc uagaaauggg cgcagccagg cacuuccuaa     1920

gaaugcaaca auuagcaaaa acacaagaag aaagagcaca auuacuucaa ccaacacuug     1980

agauaaaucc cagacaugca uuaaucaaaa aacuaaacca acuucgugca agcgaaccag     2040

gauuagcaca acuuuuaguu gaucaaauau augaaaacgc aaugauagca gcuggacucg     2100

ucgaugaucc aagagcaaug gugggacgcc uuaaugaauu auugguaaaa gcauuggaac     2160

gacauuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  3219
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt6)

<400>  3219
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

aaauaucauc acuaccaaca caacuauuca aaugcugcuu cugcgacuuc cuaaaaguaa      120

aaaugcacac aaugucauca ucacaccuau ucuaccuagc acuaugccua cuaacauuca      180

caucaucagc aacagcagga ccagaaacac uaugcggcgc agaacuagua gacgcauuac      240

aauucguaug cggagacaga ggauucuacu ucaacaaacc aacaggauac ggaucaucau      300

caagaagagc accacaaaca ggcauaguag acgaaugcug cuuccgauca ugcgaccuaa      360

gaagacuaga aauguacugc gcaccacuaa aaccagcaaa aucagcaaga ucaguaagag      420

cacaaagaca cacagacaug cccaaaacac aaaaagaagu acaccuaaaa aacgcaucca      480

gaggaucagc aggaaacaaa aacuacagaa uguaaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  3220
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt6)

<400>  3220
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

uaccaauggg aaaaucaaug cuaguacuau uaacauuucu agcauuugca agcuguugca      120

uugcagcaua cagaccauca gaaacacuau guggaggaga auuaguagau acauuacaau      180

uuguaugugg agauagagga uucuauuucu caagaccagc aucaagaguu agcagaagaa      240

guagaggaau aguagaagaa ugcuguuuca gaagcuguga uuuagcauua cuagaaacau      300

auugcgcaac accagcaaaa agugaaagag auguaucaac accaccaacu guauuaccag      360

auaacuuucc aagauaccca guaggaaaau ucuuucaaua cgauacaugg aaacaaagca      420

cacaaagacu aagaagagga cuaccagcau uauuaagagc aagaagagga cacguucuag      480

caaaagaacu agaagcauuu agagaagcaa aaagacauag accacuaaua gcauuaccaa      540

cacaagaucc agcacacgga ggagcaccac cagaaauggc aucaaacaga aaauaaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  3221
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt6)

<400>  3221
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaauu       60

ccuucucaac aucagccuuc ggaccaguag ccuucucacu aggacuacua cuaguacuac      120

ccgcagcauu cccagcacca gucccaccag gagaagacuc aaaagacgua gcagcaccac      180

acagacaacc auuaacauca ucagaacgaa uagacaaaca aauaagauac auauuagacg      240

gaauaucagc acuaagaaaa gaaacaugca acaaaucaaa caugugcgaa ucaucaaaag      300

aagcccuagc agaaaacaac cuuaaucuac caaaaauggc agaaaaagac ggaugcuucc      360

aaucaggauu caacgaagaa acaugccuag uaaaaauaau aacaggacua cuagaauucg      420

aaguauaccu cgaauaccua caaaacagau ucgaauccuc agaagaacaa gcccgagcag      480

uccaaauguc aacaaaagua cuaauacaau ucuuacaaaa aaaagcaaaa aaucuagacg      540

caauaacaac accagaccca acaacaaacg ccuccuuacu aacaaaacua caagcacaaa      600

accaaugguu acaagacaug acaacacacc ucauacuaag aucauucaaa gaauuccuac      660

aauccucacu aagagcacuu agacaaaugu aaggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  3222
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt6)

<400>  3222
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uacugugguu aagagguuuc cuauuagcaa gcugcuggau aauaguaaga agcaguccaa      120

caccagggag cgaaggacac agugcggcac cagacugccc aucaugugcg cuagcagcau      180

uaccaaaaga cguuccaaau agucaaccag aaaugguuga agcaguaaaa aaacauauau      240

uaaauaugcu acaucuaaaa aaaagaccag auguaacaca accaguaccg aaagcagcau      300

uauuaaaugc aauacgaaaa uuacaugucg gaaaaguagg agaaaacgga uauguagaaa      360

uagaagacga cauuggaaga agagcagaaa ugaacgaauu aauggaacaa acaagugaaa      420

uuauaacguu ugcagaauca ggaacagcca gaaaaacacu acacuuugaa auaucaaaag      480

aaggcucaga ccuaucaguu guagaaagag cggaaguaug guuauuucua aaaguaccua      540

aagcaaacag aacaagaaca aaaguaacaa uuagacuauu ucaacaacaa aaacacccac      600

aaggaagucu agauacagga gaagaagcag aagaaguagg auuaaaagga gaaaggagug      660

aauuacuauu aagugaaaaa guaguagacg caagaaaauc aacauggcac guauuuccag      720

uaucaucaag cauacaacga cuacuagacc aaggaaaauc cucauuagau guaagaaucg      780

caugcgaaca augucaagaa aguggugcau cauuaguacu auuaggaaaa aaaaaaaaaa      840

aagaagaaga aggagaagga aaaaaaaaag gaggaggaga aggaggugca ggagcagacg      900

aagaaaaaga acaaagccau agaccauucu uaauguuaca agcaagacaa agugaagacc      960

auccucauag gagaagaaga agaggacuug aaugcgacgg aaaaguaaau auauguugua     1020

aaaaacaauu cuuuguaagc uuuaaagaua uaggauggaa cgauuggaua auagcuccaa     1080

guggauauca cgcaaauuac ugcgaaggag aaugcccauc acacauagcg ggaacaagcg     1140

gaagcucacu aucauuccau agcacaguaa uaaaccauua cagaaugaga ggacauaguc     1200

cauucgcaaa cuuaaaauca ugcugugucc caacaaaacu aagaccaaug uccauguuau     1260

auuaugauga cggucaaaau auaauaaaaa aagauauaca aaacaugaua guagaagaau     1320

guggcuguag cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  3223
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt6)

<400>  3223
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaug       60

gauuacccgg gagggcacua ggugcagcuu gccuauuacu acuagcagca ggauggcuag      120

gaccagaagc auggggaagc ccgacaccac cuccuacacc agcagcacca ccaccaccuc      180

cuccaccagg aucaccagga ggaagucaag acacauguac aucaugcgga ggauuccgaa      240

gaccagaaga acuaggaaga guagauggag auuuucuaga agcaguuaaa cgacauauac      300

uaucuagacu acaaaugcga ggaagaccaa auauaacaca cgcaguucca aaagcagcaa      360

ugguaacagc acuuagaaaa uuacaugcag guaaaguacg ugaagaugga agaguagaaa      420

uaccacaucu agacggucac gcuucaccag gagcugacgg ucaagaaaga guaucagaaa      480

ucaucagcuu ugccgaaacu gauggacuag caucaucacg aguuagauua uauuuuuuua      540

uuaguaauga aggaaaucaa aauuuauucg uuguccaagc uucauuaugg cuuuauuuaa      600

aauuacuacc uuauguauua gaaaaaggau caagaagaaa aguaagaguu aaagucuauu      660

uccaagaaca aggucaugga gauagaugga auaugguaga aaaaagagua gaccuaaaaa      720

gaucaggaug gcacacuuuc ccauuaacag aagcaauaca agcauuauuc gaaagaggag      780

aaagaagacu aaauuuagac guucaaugug acucauguca agaauuagca guaguaccag      840

uuuuugucga uccaggagaa gaaagucaua gaccuuuugu aguaguacaa gcgagauuag      900

gagauucaag acacagaaua aggaaaagag gauuagaaug ugacgggaga acaaacuuau      960

guuguagaca acaauuuuuu auagauuuuc gacuaauagg auggaaugau uggauaauag     1020

caccuacagg auauuaugga aauuauugug aaggaaguug uccagcauau uuagcaggag     1080

uaccaggauc agcaagcagu uuucauacag caguaguuaa ucaauauaga augagaggac     1140

uaaauccugg aacgguaaau ucguguugca uuccuacaaa acuaucaaca augagcaugu     1200

uauacuucga ugacgaauau aauauaguua aaagagacgu accaaacaug auuguagaag     1260

aauguggaug ugcuugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  3224
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt6)

<400>  3224
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcuc       60

ucagaguacu acuacuaacu gcacuaacuu uaugccacgg cuucaacuua gauaccgaaa      120

acgccaugac uuuucaagaa aaugcaagag guuucggaca aucuguagua caacuacaag      180

gcucaagggu aguuguaggc gccccucaag aaaucguagc cgcuaaucag cgagguucuc      240

uuuaucaaug ugauuauuca acuggauccu gugaacccau ccgauuacaa guaccuguag      300

aagcuguaaa uaugucacuu ggacuaaguc ucgcugcaac aacaucaccc ccgcaacuac      360

ucgcaugugg cccaaccgua caucagacau guucugaaaa cacauacgua aaaggauuau      420

guuuccuauu uggcaguaac uuacgacaac aaccacaaaa auucccagaa gccuuaagag      480

gauguccuca agaagauagc gauauugcau uccucauaga uggaucuggu uccauuauac      540

cucaugauuu ccggcgaaug aaagaauuug uuucaacagu cauggaacaa cuaaagaaau      600

caaaaacauu auuuuccuua augcaauaua gugaagaguu ccgaauacau uuuaccuuca      660

aagaauuuca aaauaaccca aacccgcgaa gucucguaaa acccauuacc caacuucuag      720

guagaacuca cacagcaaca gguauuagaa aaguuguucg agaguuauuu aauauuacaa      780

acggagcacg uaaaaacgcu uucaaaaucc uaguuguaau aacagacgga gaaaaauuug      840

gugacccacu agguuaugaa gauguuaucc cagaggcuga cagagaagga gucauuagau      900

augucauagg aguaggagau gcauuccgca gugagaaaag uagacaggaa cuuaacacga      960

uagccucuaa acccccaagg gaucacgucu uccaaguaaa caacuuugag gcuuuaaaaa     1020

ccauacaaaa ccaauugcgu gagaaaauuu uugcuauaga agggacacaa acuggauccu     1080

caucuucauu ugaacaugaa augucucaag aaggauuuuc agcagccauc acaucaaacg     1140

gaccuuuacu aucaaccguu ggcuccuaug auugggcugg aggagucuuc cuuuauacuu     1200

cuaaagaaaa auccacuuuu auaaauauga cccggguuga uagcgacaug aaugacgccu     1260

auuuggguua ugcagcugcu auaauacuac gaaaucgugu ccaaaguuua guccuaggag     1320

cucccagaua ucagcauauu gguuuaguug cgauguuuag acaaaacaca gguauguggg     1380

aaucaaaugc aaauguuaaa ggaacacaaa uuggggcaua uuucggcgcu ucccuauguu     1440

caguagacgu cgauucaaau ggauccacgg auuuaguucu cauaggugca ccacacuauu     1500

augaacaaac ccgagguggc caagucuccg uaugcccccu accacgcggc cgugcacguu     1560

ggcagugcga cgcuguacuu uauggugaac aaggacaacc uuggggacgu uuuggagcag     1620

cccuaacugu acuuggagac guuaauggcg acaaauuaac ggauguugcg aucggggcac     1680

caggcgaaga agauaauaga ggagccguau acuuauuuca uggcacaagc ggcucaggaa     1740

uaucaccuuc acauagucaa agaauagcag gaucaaaacu aucuccaaga uuacaauacu     1800

uugggcaaag ucuaagcggc ggacaagacc uuacaaugga uggauuagua gaucuaaccg     1860

uuggagcaca aggacaugua uuauuauuaa gaucccaacc uguucuuaga gucaaagcua     1920

uuauggaauu uaacccuaga gaaguagcuc gcaauguuuu ugaauguaau gaucagguug     1980

uuaaagguaa agaagcagga gaaguccgug uuugucuuca cguacagaaa ucaacuaggg     2040

auagacuaag agaaggacaa auacaaagug uuguuacaua ugauuuagca cuagacucug     2100

gucgaccaca uucaagagca guuuucaacg agacuaaaaa cucaacacga agacaaaccc     2160

agguauuagg uuuaacacaa acuugcgaaa cacuuaaacu acaauuaccu aauugcauag     2220

aagauccagu uucaccaaua guccuacgau uaaacuucuc auuaguuggc accccacugu     2280

ccgcuuucgg aaaccuacgu cccguccucg cagaagacgc acaaagacua uuuacagcuu     2340

uauucccuuu ugaaaagaau ugcggcaaug auaauauaug ucaagacgau cuuucaauua     2400

cuuuuaguuu uaugucacua gauugccuag uaguaggagg accaagagaa uuuaauguaa     2460

caguuacagu acgcaacgac ggagaagacu cuuaucgaac acaaguuaca uuuuucuuuc     2520

cauuagacuu aaguuaccga aaaguaucaa cccuucaaaa ucaacgauca caaagaucau     2580

ggagguuagc cugcgaaucg gcaucaucca cugaaguauc uggugcacuc aaaaguacuu     2640

cauguuccau uaaucauccu auauuuccug aaaauuccga aguaaccuuu aacauaacau     2700

uugauguuga uucaaaagcc ucucucggua auaaauuacu acuuaaagca aacgugacau     2760

ccgaaaauaa caugccaaga acuaauaaaa cggaauuuca auuagaauua ccuguuaagu     2820

acgcagucua caugguugug acaagucaug gcguuuccac aaaauaucuu aacuuuacag     2880

caagugaaaa cacaucaagg guuaugcaac aucaauauca agucaguaac cuuggucaac     2940

gaagccuacc aaucucauug gucuuucucg ucccaguaag acuaaaucaa accguaauau     3000

gggaucgacc gcaaguuacu uucagugaaa acuuaaguuc uacaugccac acaaaagaaa     3060

gacuuccauc ucacucugac uuucuagcug aacuacgaaa agcucccguu guaaacuguu     3120

cuauagcagu uugucaacgu auacaaugug auauuccauu cuuuggaaua caagaagagu     3180

ucaaugcuac auuaaaaggu aauuuaucgu uugauuggua cauuaaaacu agccauaauc     3240

auuuauuaau aguuucuacu gcagaaaucc uguuuaauga uuccguauuc acucuauuac     3300

ccggacaagg agcauuugua agaucccaaa ccgaaacaaa aguagaaccu uuugaagucc     3360

ccaacccucu uccuuuaauc guuggaucaa gcguuggcgg acuauuacuu uuagccuuaa     3420

uaacggcggc auuauauaaa uuaggauucu ucaaacgcca auauaaagau augaugucug     3480

aagguggacc uccuggagca gaaccacaau aaggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  3225
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt6)

<400>  3225
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguuuu       60

cacuaaaaac auuaccuuuc cuacuucuac uacacguaca aauaucaaaa gcauuuccag      120

ucucaucaaa agaaaaaaac acaaaaacag uacaagauua ucucgaaaaa uuuuaccaau      180

uaccaucaaa ucaauaucaa ucaacacgaa aaaauggaac aaacguaaua guugaaaaau      240

uaaaagaaau gcaaagauuc uuuggacuca augucacagg caaaccuaac gaagaaacac      300

uagacaugau gaaaaaacca agaugcggag uaccagacuc aggaggauuc auguuaaccc      360

caggcaaccc uaaaugggaa agaacaaauc uaacauacag aauacgaaac uauacaccac      420

aacuauccga agcagaaguc gaaagagcaa uaaaagacgc uuuugaacuu uggucaguag      480

ccuccccacu aauauucaca cgaauaucac aaggagaagc cgacaucaac auagcauuuu      540

aucaacgaga ccacggagac aauucccccu ucgacggacc aaauggaaua cuagcacacg      600

cauuccaacc uggacaagga auaggaggag augcacauuu cgacgcagaa gaaacaugga      660

caaacacauc agcaaacuac aaccuauucu uagucgcagc acacgaauuc ggacauucuc      720

uaggacuagc ccauucaucu gaccccggcg cacuaaugua uccaaacuac gcauuuagag      780

aaacauccaa cuacucccua ccccaagacg auauagaugg uauccaagca auauacggac      840

uauccucaaa uccaauacaa ccaacaggcc ccucuacacc aaaaccaugc gacccauccc      900

uuacauucga cgcaauaaca acccuccgag gagaaauauu auucuuuaaa gacagauacu      960

ucuggagaag acacccucaa cuccaacgag uugaaaugaa cuucauaucu uuauuuuggc     1020

caucucuacc aacagggauc caagcagcuu acgaagauuu ugaucgcgac uuaauauuuu     1080

uauucaaagg aaaucaauac ugggcauuau caggauauga uauacuacaa ggauacccca     1140

aagacauauc aaauuaugga uuccccuccu caguccaagc caucgacgcu gcaguauucu     1200

accgaucaaa aaccuacuuc uuuguaaaug accaauuuug gagauacgau aaucaacguc     1260

aauucaugga accugguuau ccaaaaucaa uaucuggcgc auuucccgga auagaaagca     1320

aaguagacgc agucuuucaa caagaacacu ucuuccacgu auuuagcgga ccaagauacu     1380

acgccuuuga cuuaauagca caaagaguaa cacgaguugc aagaggaaac aaauggcuaa     1440

acuguagaua cggauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  3226
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt6)

<400>  3226
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaguc       60

uauggcaacc auuaguauua guuuuacuug uacucgguug uugcuucgcu gcaccuagac      120

aacgucaauc aacccucgug cucuuuccag gagaucuucg aacuaauuua acagauagac      180

aauuagcaga agaauauuua uauagguaug gcuauacacg aguagcugaa augcgaggag      240

aaaguaaaag ccuaggaccu gccuuauuac uacuacaaaa acaacuauca uuaccagaaa      300

cuggagaauu agacuccgcu acucuaaaag caaugcgcac cccacguugc ggaguaccag      360

auuuaggacg auuucaaaca uuugaaggag auuuaaaaug gcaucaucac aauauaacau      420

acuggauuca aaacuacagu gaagauuuac ccagggcagu aauagacgau gcauuugcaa      480

gggcauuugc auuaugguca gcuguuacuc cacucacuuu cacuagaguu uacaguagag      540

augcagauau cguaauacaa uuuggaguag cagaacacgg cgacggauac ccauucgacg      600

guaaagaugg acuacuagcu caugccuucc caccaggucc agguauacaa ggagacgcac      660

auuuugauga ugaugaauua uggaguuuag gcaagggagu ugucguacca acucgauuug      720

gaaaugcuga uggugcagcu ugccauuuuc ccuuuauuuu cgaagggaga ucguauucag      780

cuugcacaac agacggaaga uccgaugguc uaccauggug cucuacaaca gcuaacuaug      840

acacagacga uagauucgga uucugcccau ccgaacgauu auauacucaa gauggaaaug      900

cagacgguaa accaugucaa uucccauuua uauuccaagg acaaucauau agcgcuugca      960

caacagaugg aagaagcgau ggauacagau ggugcgcaac aacagcuaac uaugaucgag     1020

acaaacuauu uggauuuugu ccaacacgug cugauuccac aguaauggga ggaaauucug     1080

cuggugaacu auguguauuc ccauuuacau uccuugguaa agaauacucu acauguacaa     1140

gcgaaggcag aggcgacgga agacuuuggu gugcuacaac aucuaauuuu gauagugaua     1200

aaaaaugggg auucugucca gaccaaggau acucauuauu ucuaguagcu gcacaugaau     1260

uuggacaugc cuuaggauua gaucauaguu cuguaccaga agcucugaug uauccuaugu     1320

accgauucac ugaaggacca ccacuccaua aagacgaugu uaauggaaua agacauuugu     1380

acggacccag gccagaacca gaaccaagac caccaacaac aacaacuccu caaccgacag     1440

caccaccaac aguuugucca acaggacccc ccacaguaca uccaucagaa agaccuacag     1500

caggaccaac agguccgcca ucagccggac caacuggacc uccaacagca ggccccucca     1560

cagcaacaac aguaccauua ucaccaguag augaugcaug caauguaaau auauuugaug     1620

cuauagcaga gauaggcaau caacuauauc ucuuuaaaga cggaaaauau uggagauucu     1680

cagagggcag aggaucaaga ccccaaggac cauuuuuaau ugcagauaaa uggccagcuu     1740

uaccaaggaa auuagauuca gucuuugaag agcgccucuc aaaaaaauua uuuuuuuucu     1800

caggaagaca agucuggguu uauaccggag cauccguauu aggaccaaga agauuagaca     1860

aauuagguuu aggugcugau gucgcacaag uuacaggagc uuuacgaagc ggucgaggaa     1920

aaaugcuacu guucucuggu agaagacuau ggagauuuga cguaaaagcg caaaugguag     1980

acccucgaag cgcuagugaa guagauagaa uguucccugg uguaccucuu gacacccaug     2040

acguuuuuca auacagagaa aaagcauauu uuugccaaga ucgcuucuac uggcgaguua     2100

guucacguag cgaacuaaau caaguagacc aaguuggaua ugucacauac gauauacuac     2160

aauguccaga agacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  3227
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt6)

<400>  3227
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

cagguguacu ugcagccuuc uuauuuuuau cauggacuca cuguagagca cucccacuac      120

caucaggagg agacgaagau gauuuaucag aagaagaccu ccaauucgca gaaagauauc      180

uaagaucuua cuaucaccca acaaacuuag cagguauacu aaaagaaaac gcagcaucau      240

caaugacaga aagacuaaga gaaaugcaau cauucuuugg auuagaagua acaggaaaac      300

uagaugauaa uacacuagac guaaugaaaa aacccagaug cggaguaccu gauguaggag      360

aauacaacgu auucccaaga acacuaaaau ggucaaaaau gaaucuaaca uacagaaucg      420

uaaacuauac cccagacaug acacauagug aaguagaaaa agcauucaaa aaagcauuca      480

aaguaugguc agacguaaca ccauuaaacu ucaccagacu ucacgaugga auagcagaca      540

uuaugauuuc auuuggcaua aaagaacaug gcgacuucua cccauucgac gguccaagcg      600

guuuacuagc ccaugcauuc ccaccuggac cuaacuaugg cggagacgca cacuuugacg      660

augacgaaac auggaccagu ucaaguaaag gauacaaucu auuuuuggua gcugcccacg      720

aauucggcca cucacuagga cuagaccauu caaaagaccc uggugcauua auguucccaa      780

uauauaccua uacaggaaaa ucacauuuca uguuaccaga ugaugaugua caaggcaucc      840

aaucauuaua cggcccagga gacgaagauc caaacccaaa acacccaaaa acaccagaca      900

aaugcgaccc uucacuaucu cuagacgcaa uaacuucuuu aagaggagaa acaaugauau      960

ucaaagaucg auucuucugg agacuucacc cacaacaagu agaugcagaa cuauucuuaa     1020

caaaaucuuu cuggccagaa cuaccaaacc guaucgacgc agcauaugaa cacccaucac     1080

augacuuaau auuuauauuu agaggacgaa aauuuugggc auuaaacgga uaugauauau     1140

uagaaggaua cccuaaaaaa auaucagaac ucggauuacc aaaagaaguu aaaaaaauau     1200

cggcagcugu acacuucgaa gacacaggca aaacccuauu auuuucagga aaccaaguau     1260

ggcgauauga cgacacaaau cauauaaugg auaaagauua cccaagauua auagaagaag     1320

auuucccagg aauaggugac aaaguagacg caguauacga aaaaaauggu uacauauauu     1380

uuuuuaacgg acccauacaa uucgaauacu caauaugguc aaacagaaua guacgaguca     1440

ugccagcaaa uucgauacuu uggugcuaag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3228
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt6)

<400>  3228
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

caccaaacac aacagaagac uacgauacaa caacugaauu cgacuacgga gacgcaacac      120

caugucaaaa agucaacgaa cgagcauucg gagcacaauu acuaccucca cuauacucau      180

uaguauuugu aauaggcuua gucggaaaca uacuaguagu acuaguuuua guucaauaca      240

aaagacuaaa aaacaugaca ucuauauacu uacuaaacuu agcaauauca gaucuucuau      300

ucuuauucac ccuuccauuc uggauagacu acaaauuaaa agacgacugg guauucggcg      360

acgcaaugug caaaauauua uccggauucu auuacacagg acuauacuca gaaauauuuu      420

ucauaauacu ccuaacaaua gacagauacc uagcaauagu ucacgcagua uucgcuuuaa      480

gagcaagaac cguaacauuc ggaguuauaa caucaauuau aaucugggca cuagccauac      540

uagccucaau gccaggacua uacuucucua aaacucaaug ggaauucaca caccauacau      600

guucacucca cuuuccccau gaauccuuaa gagaauggaa acucuuccaa gcacuaaaau      660

uaaacuuauu cggacuagua uuaccacuac uaguaaugau aauaugcuac acaggaauua      720

uaaaaauccu acuuagaaga ccaaacgaaa aaaaaucaaa agcagucaga cuaauauucg      780

ucauaaugau aaucuuuuuu uuauucugga caccuuacaa ucucacuauc uuaauaucag      840

uuuuccaaga cuuccuauuc acacacgaau gugaacaauc aagacacuua gacuuagcag      900

uacaagucac ugaaguaaua gcauacacac acugcugcgu aaacccagua aucuacgcau      960

ucguaggaga aagauuuaga aaauaccuaa gacaacuauu ccacagaaga guugcuguac     1020

accuaguaaa augguuaccc uucuuaucag ucgaucguuu agaaagaguc ucaucaacau     1080

cacccucaac aggugaacac gaacuaucag ccggauuuua aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  3229
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt6)

<400>  3229
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagaa       60

cauuagcaug cuuauuacua uuaggaugug gauacuuagc acacguauua gcggaagaag      120

cagaaauacc aagagaagua auagaaagac uagcacgauc acaaauacac ucaauaaggg      180

accuacaaag auuacuagaa auagacucag uaggaagcga agacucacua gacacaucau      240

uaagagcaca cggaguacac gcaacaaaac acguaccaga aaaaagacca cuaccaauaa      300

gaagaaaaag aagcauagaa gaagcaguac cagcaguaug caaaacaaga acaguaauau      360

augaaauacc acgaucacaa guagacccaa caucagcaaa cuucuuaaua uggccaccau      420

gcguagaagu gaaaagaugc acaggcugcu gcaacacauc gucaguaaaa ugccaaccaa      480

gcagaguaca ccacagauca guaaaaguag cuaaaguaga auacguaaga aaaaaaccaa      540

aacuaaaaga aguacaagua agacuagaag aacaccuaga augcgcaugc gcaacaacaa      600

gccuaaaccc agacuaccga gaagaagaua caggaagacc gcgagaaagu ggaaaaaaac      660

gaaaaagaaa aagacuaaaa ccaaccuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  3230
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt6)

<400>  3230
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaua       60

gaugcugggc acuauucuua agcuuauguu gcuacuuaag acuaguauca gcagaaggag      120

auccaauacc agaagaauua uacgaaaugc uaagcgacca cucaaucaga agcuuugacg      180

auuuacaaag acuacuacau ggagauccag gagaagaaga cggagcagaa cuagacuuaa      240

auaugacaag aucacacuca ggaggagaau uagaaucacu agcaagagga agaagaaguc      300

uaggaucacu aacaauagcg gaaccagcaa ugauagcaga auguaaaaca cgaacagaag      360

uauucgaaau aucaagaaga uuaauagaca gaacaaaugc aaacuuccua guauggccac      420

caugcguaga aguacaaaga ugcucaggau guugcaauaa cagaaacgua caauguaggc      480

caacacaagu acaauuaaga ccagugcaag uaagaaaaau agaaauagua cguaaaaaac      540

caauauuuaa aaaagcaaca guaacacuag aagaccaucu agcauguaaa ugcgaaacag      600

uagcagcggc cagaccagua acaagaagcc caggaggaag ucaagaacaa agagcaaaaa      660

caccacaaac uagaguuaca auaagaacag uaagaguaag aagaccacca aaaggaaaac      720

auagaaaauu caaacacaca caugauaaaa cagcacuaaa agaaaccuua ggagcaugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  3231
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt6)

<400>  3231
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcu       60

uauucggacu acuacuccuu acuucagcac uagcaggaca aagacaagga acacaagcag      120

aaucaaaccu aagcucaaaa uuccaauuuu caucaaacaa agaacaaaau ggaguacaag      180

auccacaaca cgaaaggauu auuacagucu caacaaacgg aaguauacac aguccaagau      240

ucccacauac auacccaaga aacacaguuu uagucuggcg acuaguagca guagaagaaa      300

auguauggau acaacuaaca uucgaugaaa gauucggauu agaagaccca gaagacgaca      360

uaugcaaaua ugacuuugua gaagucgaag aaccaaguga cgguacaaua cuaggaagau      420

ggugcggauc aggaacagua ccaggcaaac aaauaaguaa aggaaaccaa auuagaauaa      480

gauucguauc agaugaauac uuuccaucag aaccaggauu cugcauacau uacaacauag      540

uaaugccaca auucaccgaa gcaguuucac caucaguuuu accaccaagu gcccucccau      600

uagaccuacu aaacaacgca auaacugcau ucaguacucu agaagaccua auaagauacc      660

uagaaccaga aagauggcaa uuagaucucg aagaccuaua uagaccaaca uggcaacuau      720

uaggcaaagc auuuguauuc ggaagaaaau caagaguagu agacuuaaac cuauuaacag      780

aagaaguaag acuauacagc ugcacaccaa gaaacuuuuc aguuucaaua agagaagaau      840

uaaaaagaac agauacaauc uucuggccag gaugucuauu agucaaaaga ugcggcggaa      900

acugcgcaug cugccuacau aacugcaacg aaugccaaug cguaccaagu aaaguaacaa      960

aaaaauacca cgaaguauua caacuaagac caaaaacugg aguaagaggu cuacacaaau     1020

cacuaacuga cguagcauua gaacaucacg aagaauguga cugcgucugc agaggaucaa     1080

caggaggaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  3232
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt6)

<400>  3232
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gacuaauauu cguauacaca cucauaugcg caaauuucug cucauguaga gacacaucag      120

caacaccaca aucagcauca auaaaagcac uaagaaacgc caaccuaaga cgagacgauu      180

uauacagaag agacgaaaca auacaaguaa aagguaacgg auauguacaa ucaccaagau      240

ucccaaacag uuacccaaga aaucuacuac uaacauggag acuacacuca caagaaaaca      300

caagaauaca acuaguauuu gacaaccaau uuggacuaga agaagcugaa aacgacauau      360

guagauauga cuucguagaa guagaagaca uaagugaaac aucaacaaua auuagaggaa      420

gauggugcgg ccacaaagaa guaccacccc gaauaaaauc aaggacaaac caaaucaaaa      480

uaacuuucaa aucagacgac uacuuuguag caaaaccagg cuuuaaaaua uacuauagcu      540

uacuagaaga cuuccaacca gcagccgcaa gugaaacaaa cugggaaagc guaacaucaa      600

gcaucucagg aguaagcuau aacucaccau caguaacaga cccaacacua auagcagacg      660

cauuagacaa aaaaauagca gaauucgaca caguagaaga uuuauuaaaa uacuucaacc      720

cagaaucaug gcaagaagac cuagaaaaua uguaccucga cacaccaaga uauagaggaa      780

gaagcuauca cgauagaaaa ucaaaaguag accuagacag acuaaaugac gacgcuaaac      840

gauauaguug uacaccaaga aacuacagug ucaacauacg agaagaacua aaacuagcaa      900

acguaguauu cuuuccacga ugucuacuag uacaaagaug uggaggaaac ugcggaugcg      960

gaacaguaaa uuggagauca ugcaccugca acagcggaaa aacaguuaaa aaauaccacg     1020

aaguacuaca auucgaaccu ggccacauaa aacgaagggg aagagcaaaa accauggcac     1080

uaguagauau ccaacuagau caucacgaga gaugugacug uauauguagu ucaagaccac     1140

caagauaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  3233
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt6)

<400>  3233
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguaa       60

cacacucaaa auucccagca gcaggaaugu caagaccauu agacacauca uuaagacuaa      120

aaacauucuc aucaaaauca gaauaucaac uaguaguaaa cgcaguaaga aaacuacaag      180

aaucaggauu cuacugguca gcaguaacag gaggagaagc caaccuacuc cuaucagcag      240

aaccagcagg aaccuuccua auaagagacu caucagacca acgacacuuc uucacacuau      300

caguaaaaac acaauccgga acaaaaaacc ucagaauaca augcgaagga ggaucauucu      360

cacuacaauc agacccacgc uccacacaac caguaccaag auucgacugc guacuaaaac      420

uaguacacca cuacaugcca ccaccaggag ccccaucauu uccaucacca ccaacagaac      480

caucaucaga aguacccgaa caaccaucag cacaaccacu ccccggauca ccaccaagaa      540

gagcauacua cauauacuca ggaggagaaa aaauaccauu aguacuaucc agaccauuau      600

cuucaaacgu cgcaacacua caacaucuau gcagaaaaac aguaaacgga cacuuagacu      660

cauacgaaaa aguaacccaa cuaccaggcc ccauacgaga auuccuagac caauacgacg      720

caccacuaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  3234
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt6)

<400>  3234
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguac       60

caucagcagg acaauuagca uuauucgcau uaggaauagu auuagcagca ugucaagcau      120

uagaaaauuc aacaucacca cuaucagcag auccaccagu agcagcagcu guaguaucac      180

auuuuaauga cuguccagau ucacauacuc aauucuguuu ucauggaaca uguagauucu      240

uaguacaaga agacaaacca gcauguguau gucauucagg auauguagga gcaagaugug      300

aacaugcaga uuuauuagca guagucgcag caucacaaaa aaaacaagca auaacagcau      360

uaguaguagu aucaauagua gcauuagcag uacuaauuau aacaugugua cuaauacauu      420

guugucaagu aagaaaacau ugugaauggu gcagagcauu aauauguaga caugaaaaac      480

caucagcauu auuaaaagga agaacagcau guugucauuc agaaacagua guauaaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  3235
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt6)

<400>  3235
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

cuagcggacu cagauuauua cccuuacuac ucccacuccu auggcuacua guacuaacuc      120

caggaagacc agcagcagga cuaaguacau guaaaacuau agacauggaa uuaguaaaaa      180

gaaaaagaau agaagccaua cguggacaaa uccuaucuaa auugagacua gccucaccuc      240

caucacaagg agaaguacca ccaggacccc uacccgaagc aguacuagca cuauacaacu      300

caacaagaga uagaguagca ggagaaucag cagaaccaga accagaacca gaagcagauu      360

auuacgcaaa agaaguaaca cgcguauuaa ugguagaaac acauaacgaa auauaugaua      420

aauucaaaca aucuacacac ucuauauaca uguucuuuaa uacaucagaa cucagagaag      480

ccguacccga accaguauua uuaucaagag cagaacuaag acuucuaaga cuaaaacuca      540

aaguugaaca acacguagaa cuauaccaaa aauacucaaa caauucuugg agauauuuau      600

cuaacagacu acuagccccc ucagacuccc cugaauggcu aucauucgac guaacaggag      660

uagucagaca augguuaucu agaggaggag aaauagaagg auuccgacuu ucagcacacu      720

guucuuguga uagucgcgac aacacauuac aaguagacau aaacgguuuc acaacuggac      780

guagaggaga ccuugcaaca auacauggua ugaacagacc auucuuacua cuaauggcaa      840

caccacucga acgagcacaa caucuacaau ccucacgcca cagacgagcc cuagacacaa      900

acuacugcuu cucaucaacc gaaaaaaauu guugcguaag acaauuauac auagauuuca      960

gaaaagaccu aggauggaaa uggauacaug aaccuaaagg auaccacgcc aauuuuuguu     1020

uaggcccaug uccauacaua uggucacuag acacacaaua cucuaaagua uuagcucuau     1080

acaaccaaca caacccaggc gcaucagcag caccaugcug uguuccacaa gcuuuagaac     1140

cauuaccaau cguauauuac guaggaagaa aacccaaagu agaacaauua ucaaacauga     1200

uagucagauc auguaaaugc ucuuaaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  3236
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt6)

<400>  3236
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcauu       60

acugcguacu aucagcauuc cuaauacuac accuaguaac aguagcauua ucccuaucaa      120

cuugcuccac ccuagacaug gaccaauuua ugagaaaacg cauagaagca auaagaggac      180

aaauuuuauc aaaacucaaa cuaacaagcc caccagaaga cuacccagaa ccagaagaag      240

uaccaccgga agucauuuca auauacaauu caacaagaga ccuacuacaa gaaaaagcau      300

caagaagagc ugcagcaugu gaaagagaac gcagcgacga agaauacuac gcaaaagaag      360

uauacaaaau cgacaugccu ccauucuucc caagcgaaaa cgcaauacca ccaacauucu      420

aucgaccaua uuuuagaaua guaagauucg acgucucagc cauggaaaaa aaugcuagca      480

auuuaguaaa agcagaauuu agaguuuuca gacuacaaaa cccaaaagca cgaguccccg      540

aacaacgaau agaauuauac caaauacuaa aaucaaaaga ccuaacaucc ccaacacaaa      600

gauacauaga cucaaaagua guuaaaaccc gagcagaagg cgaauggcua ucuuucgaug      660

uaacagacgc aguacacgaa ugguuacacc acaaagauag aaaccuaggu uucaaaauau      720

cucuccacug cccaugcugc acauucguac cauccaacaa cuacauaaua ccaaacaaau      780

cugaagaauu agaagcaaga uucgcaggaa uagacgguac aucaaccuac acaucaggag      840

aucaaaaaac aauaaaaucc acaagaaaaa aaaauucagg aaaaacacca caccuacuac      900

uaaugcuacu accaagcuac agauuagaau cacaacaaac aaacagacga aaaaaaagag      960

cacuagaugc agcauacugc uucagaaacg uacaagacaa cugcugucuc cgcccacuau     1020

acauagauuu caaacgagau uuaggaugga aauggauaca cgaacccaaa ggauauaacg     1080

ccaacuucug cgcaggagca ugcccauauu uauggucauc cgacacccaa cacuccagag     1140

uccuaucucu cuacaacacc auaaacccag aagcaucagc aucacccugc uguguauccc     1200

aagacuuaga accacuuaca auauuauacu acauaggaaa aacaccaaaa auagaacaac     1260

uaucaaacau gauagucaaa uccuguaaau gcucauaagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  3237
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt6)

<400>  3237
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

ugcacuuaca aagagcauua guuguacuag cacuucucaa cuuugcaaca guaucacuau      120

cauuaucaac cugcacaaca cuagacuuug gacacauaaa aaaaaaacga guagaagcca      180

uaagaggaca aauacuauca aaacuaagac uaacaucacc accagaacca accguaauga      240

cacacguccc auaccaagua uuagcccuau acaacaguac aagagaacua cucgaagaaa      300

ugcacggaga acgagaagaa ggaugcacuc aagaaaauac agaaucagaa uacuacgcaa      360

aagaaauaca caaauuugau augauacaag gauuagcaga acacaaugaa cuagccguau      420

gcccaaaagg aauaacauca aaaguauuua gauuuaacgu aucaucaguc gaaaaaaacc      480

gcacaaaucu uuucagagca gaauuucgag ugcuacgagu accaaaucca ucaucaaaaa      540

gaaacgaaca acgcauagaa cuauuucaaa uccuacgacc agacgaacac auagcaaaac      600

aaagauacau aggaggcaaa aaccucccca caagagguac cgcagaaugg uuaucauucg      660

augucaccga cacaguacga gaaugguuac uaagaagaga aucaaaccua ggcuuagaaa      720

uaucaaucca cugcccaugc cacaccuuuc aaccaaaugg agacauauua gaaaacauac      780

acgaaguuau ggaaauaaaa uucaaaggag uagauaauga agaugaccac ggacgaggug      840

aucuuggaag acuaaaaaaa caaaaagacc accacaaccc acaucuaaua uuaaugauga      900

uaccuccaca cagauuagac aaccccggac agggaggaca aagaaaaaaa agagcacuag      960

auacaaacua uugcuucaga aaccuagaag aaaacugcug cgucagaccu uuauacauag     1020

auuucagaca agaucucgga uggaaauggg uccacgaacc aaaaggauac uaugcaaacu     1080

uuugcuccgg ccccugccca uaucuacgau cagcagacac aacacacuca acaguacucg     1140

gacuuuauaa cacucuaaac cccgaagcau ccgccucccc augcuguguu ccacaagacu     1200

uagaaccacu aacaauauua uacuauguag gacgaacacc aaaaguugaa caauuaagca     1260

acaugguagu aaaaucaugc aaauguagcu aaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3238
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt6)

<400>  3238
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

ccguagcugu cugggcagca uuagcaguug gauuagaauu augggcagcu gcccacgcac      120

uaccagccca aguagcauuc acaccuuacg ccccagaacc uggaucuacc ugcagacuaa      180

gagaauauua cgaucaaaca gcucaaaugu guuguucaaa auguucacca ggccaacaug      240

caaaaguauu cuguacaaaa acaucagaua caguauguga uucaugcgaa gauucaacuu      300

auacacaauu auggaauugg guucccgaau gccuauccug uggaucaaga uguucaucag      360

aucaaguaga aacccaagca uguacaagag aacaaaauag aauauguaca ugcagaccag      420

guugguauug ugcacuaagc aaacaagaag gaugcagauu augugcccca uuaagaaaau      480

gucgaccagg cuucggagua gcacgaccug gaaccgaaac cucugaugua guaugcaaac      540

caugugcacc aggaacauuu ucaaacacaa caucuucaac agacauaugc agaccacacc      600

aaauauguaa cguuguagca auaccuggca augccucaau ggaugcaguu uguacaucaa      660

cauccccaac aagaucuaug gcaccaggag ccguacauuu accacaacca guuaguacuc      720

gaucacaaca uacccaaccc acacccgaac cauccacugc uccguccacc ucauuccuac      780

uaccaauggg acccucucca ccagcugaag guucuacagg agacuucgca cuaccaguug      840

gauuaauagu aggaguaacc gcacuaggac uucuaaucau aggaguaguu aauuguguaa      900

ucaugacuca aguuaaaaaa aaaccuuuau guuuacaacg agaagcaaaa guaccacauu      960

uaccggcaga uaaagcaaga ggaacucaag gaccagaaca acaacaucua uuaauuacag     1020

cuccaucauc aucaucauca ucacuagaau caucagcuuc agcacuugau cgaagagcac     1080

cuacacguaa ccaaccacaa gcaccaggug uggaagcuuc aggugcagga gaagcaagag     1140

caaguacagg aucaucagac aguucaccag gaggucaugg aacacaagua aauguaacuu     1200

guauaguaaa ugucuguagc ucaucagauc auucauccca augcucaucu caagccuccu     1260

caacaauggg agacacagau uccucuccau cagaaucacc aaaagacgaa caaguaccau     1320

uuucaaaaga agaaugugcc uucagaucac aacuagaaac accagaaacu uuauuaggau     1380

caacugaaga aaaaccgcua cccuuaggag uaccagacgc cggaaugaaa cccucuuaag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  3239
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt6)

<400>  3239
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

uaaugagauu auuuccaugu uuucuacaau uauuagcagg auuagcacua ccagcaguac      120

caccacaaca augggcauua ucagcaggaa auggaaguuc agaaguagaa guaguaccau      180

uucaagaagu guggggaaga ucauauugua gagcauuaga aagauuagua gauguaguaa      240

gugaauaucc aagugaagua gaacauaugu uuucaccaag uuguguaagu uuauuaagau      300

guacagguug uuguggagau gaaaaccuac auuguguacc aguagaaaca gcaaauguaa      360

caaugcaauu auuaaaaaua agaaguggag auagaccauc auauguugaa uuaacauuua      420

gucaacaugu aagaugugaa ugcagaccac uaagagaaaa aaugaaacca gaaagaagac      480

gaccaaaagg aagaggaaaa agaagaagag aaaaacaaag accaacagau ugucauuuau      540

guggagaugc aguaccaaga agauaaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  3240
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt6)

<400>  3240
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugacag       60

auagacaaac ugauacagca ccgaguccga guuaucauuu auuaccagga agaaggagaa      120

caguagaugc agcagcauca agaggacaag gaccugaacc agcaccagga ggagggguag      180

aaggaguugg agcuagagga guagcauuaa aauuauuugu ccaguuauua ggaugcagua      240

gauuuggagg agccguagua agggcaggag aagcagaacc aucaggggca gcacgaagug      300

caucaagugg aagagaagaa ccacaaccag aagaaggaga agaagaagag gagaaagaag      360

aagaaagagg accacaaugg cggcugggug cgagaaaacc aggaaguugg acaggagaag      420

cagcaguaug cgcagauuca gcucccgcag cgagagcacc ucaagcauua gcaagagcaa      480

gcggaagagg aggaagagua gcaagaagag gagcagaaga aucagggcca ccucauagcc      540

caaguagaag ggguagugca aguagagcag gaccaggaag agcaagcgaa acaaugaauu      600

uuuuauuaag cuggguacau uggucauuag cgcuauuacu auauuuacau caugcaaaau      660

ggagccaagc agcaccaaug gcagaaggag gaggucaaaa ccaucacgaa guaguaaaau      720

uuauggaugu uuaucaaagg ucauacugcc acccaauaga aacacuagua gauauauuuc      780

aagaauaccc agacgaaaua gaauauauau uuaaaccaag cuguguacca cuaaugagau      840

gugguggaug uugcaacgau gaaggacuag aauguguacc aacagaagaa ucuaauauaa      900

caaugcagau aaugagaaua aaaccacacc aaggacaaca uauaggagaa augaguuuuu      960

uacaacauaa uaaaugugaa uguagaccaa aaaaggauag agcaaggcaa gaaaaaaaau     1020

caguaagagg caaaggaaaa ggacaaaaaa ggaaaagaaa aaagagcaga uauaaaaguu     1080

ggagcgugua uguaggagca agaugcuguc uaaugccaug gucacuacca ggaccucauc     1140

cauguggacc auguagugaa cgaagaaaac aucuauuugu acaggaucca caaacaugua     1200

aauguagcug uaaaaauaca gauaguagau guaaagcaag gcaauuagaa uuaaaugaaa     1260

ggacuuguag augcgauaaa ccuagaaggu agggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3241
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt6)

<400>  3241
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uucuauuaag cuggguacau uggucacuug cauuauuacu auauuuacau cacgcaaaau      120

ggagccaagc agcaccaaug gcagaaggag gaggacaaaa ccaucacgaa guaguaaaau      180

uuauggaugu auaucaaagg aguuacugcc auccaauaga aacacuagug gacauauucc      240

aagaauaucc agaugaaaua gaauauauau uuaaaccaag cuguguacca cuaaugagau      300

guggaggaug cuguaacgau gaaggacuag aaugcguacc aacagaagaa agcaauauaa      360

caaugcaaau aaugagaaua aaaccacacc aaggacaaca cauaggagaa augucauucu      420

uacaacauaa caaaugcgaa ugcagaccaa aaaaagaucg agcaagacaa gaaaaaaaau      480

caguaagagg aaaaggaaaa ggacaaaaaa gaaaaagaaa aaaaagcaga uacaaaaguu      540

ggagcguaua cguaggagca agauguugcu uaaugccaug gucacuacca ggaccacacc      600

caugcggacc cuguagcgaa agaagaaaac aucuauucgu acaagaccca caaacaugca      660

aaugcucaug caaaaacaca gacucaagau guaaagcaag acaacuagaa cuaaaugaaa      720

gaacauguag augugacaaa ccaagaagau aaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  3242
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt6)

<400>  3242
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucac       60

cauuacuaag aagacuauua cuagcagcau uauuacaacu agcaccagca caagcaccag      120

uaucacaacc ugaugcacca ggacaucaaa gaaaaguagu aucauggaua gauguauaua      180

caagagcaac augccaacca agagaaguag uaguaccacu aacaguagaa uuaaugggaa      240

caguagcaaa acaauuagua cccucaugcg uaacaguaca aagaugcgga gguuguuguc      300

cagacgaugg acuagaaugu guaccuacag gucaacauca aguaagaaug caaauauuaa      360

ugauaagaua cccaaguuca caauuaggag aaaugucauu agaagaacau ucacaaugcg      420

aauguagacc aaaaaaaaaa gacucagcag uaaaaccaga cagagcagca acaccacacc      480

auagaccuca accaagaucu guaccaggau gggacucagc accaggagcu ccaucaccag      540

cagacauaac ucauccaaca ccagcaccag gacccucagc acaugcagcu ccaucaacua      600

caucagcauu aacaccagga ccagcagcag cugcugcaga cgcagcagcc ucaucaguag      660

caaaaggagg agcauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  3243
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt6)

<400>  3243
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

uauuaggauu uuucucagua gcauguucau uacuugcagc agcauuacuc cccggaccaa      120

gagaagcacc agcugcagca gcagcauucg aaucaggacu agaccuaagc gaugcagaac      180

cagacgcagg agaagcaaca gcauaugcaa guaaagaccu agaagaacaa uuaagaagug      240

uaucaucagu agacgaacua augacaguac ucuaccccga auacuggaaa auguacaaau      300

gccaauuaag aaaaggagga uggcaacaca acagagaaca agcuaaccua aacucaagaa      360

cugaagaaac aauaaaauuu gcagcagccc acuacaauac agaaauauua aaaucaaucg      420

auaacgaaug gcgaaaaaca caauguaugc caagagaagu uuguauagac guaggaaaag      480

aauuuggagu ugcaacaaau acauuuuuua aaccaccaug cgucucagua uacagaugcg      540

gaggaugcug caauagcgaa ggauuacaau guaugaauac aucaacaagc uacuuaagca      600

aaacacuauu ugaaauaaca guacccuuau cacaaggacc caaaccaguu acaauaaguu      660

uugcaaauca uacuucaugc agauguauga guaaauuaga uguuuaucgc caaguacauu      720

caauaauacg acgcagucua ccagcaacau uaccacaaug ccaagcugca aauaaaacau      780

gcccaacuaa uuauaugugg aauaaucaca ucugcagaug ucuugcacaa gaagacuuca      840

uguuuuccuc agaugcagga gacgauucaa cagacggcuu ccacgacaua uguggaccaa      900

auaaagaacu agaugaagaa acaugucaau gcgucugcag agcaggauua agaccagcau      960

cauguggacc acacaaagaa uuagacagga auuccugcca auguguaugu aaaaauaaac     1020

uauuuccauc acaaugcgga gccaaucgag aauucgacga aaauacaugc caaugugucu     1080

guaaaagaac cugucccaga aaucaaccau uaaacccugg aaaaugugcc ugugaaugca     1140

cagagucacc acaaaaaugu uuacuaaaag gaaaaaaauu ccaucaucaa acaugcuccu     1200

guuacagaag acccugcaca aacagacaaa aagcaugcga accaggauuc agcuacagug     1260

aagaaguaug cagaugugua ccaucauauu ggaaacgacc acaaauguca uaaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  3244
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt6)

<400>  3244
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguaca       60

gagaaugggu aguaguaaac guauucauga ugcuauacgu acaauuagua caagguuccu      120

caaacgaaca cggcccagua aaaagaucau cccaaagcac acuagaaaga ucugaacaac      180

aaauaagagc agcaucuuca cuagaagaac uuuuaagaau aacacacuca gaagacugga      240

aacuauggag augcagacua agacuaaaau cauucacauc uauggacagc agguccgcaa      300

gucacagauc aaccagauuc gccgcaacau uuuaugacau agaaacacuc aaaguaauag      360

acgaagaaug gcaaagaaca caaugcaguc caagagaaac auguguagaa guagccucag      420

aacuaggaaa aagcacuaac acauucuuca aaccaccaug cguaaaugua uucagaugcg      480

gcggauguug caacgaagaa ucucucauau guaugaacac aaguacauca uacaucucaa      540

aacaacuauu cgaaauauca gucccauuaa caucaguacc agaacuagua ccaguaaaag      600

uagcaaacca cacaggaugu aaaugccuac caacagcacc aagacaccca uacaguauca      660

uaagaagauc aauccaaaua ccagaagaag accgaugcuc ccacucaaaa aaauuaugcc      720

caauagacau gcuaugggau ucaaacaaau gcaaaugcgu acuacaagaa gaaaacccau      780

uagcaggaac agaagaccac ucucacuuac aagaaccagc auuaugcgga ccacauauga      840

uguucgacga agauagaugu gaauguguau gcaaaacucc augcccaaaa gaccuaauac      900

aacacccaaa aaacugcuca uguuucgaau gcaaagaauc ucuagaaaca ugcugccaaa      960

aacacaaauu auuucaccca gacacaugcu caugcgaaga cagaugcccu uuccacacca     1020

gaccaugugc cagcggaaaa acagcaugug caaaacacug uagauuucca aaagaaaaac     1080

gagcagccca aggaccacac ucaagaaaaa auccauaagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  3245
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt7)

<400>  3245
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcgaugagac cggcuucgaa cacuccgggc ugugggugag uguccucgcc ggucuguugc      120

ugggcgcaug ccaggcccau cccaucccag acagcucccc gcuccugcaa uuugggggcc      180

aggugaggca gcgguacuug uauacugaug acgcgcagca aaccgaggcc caccuggaaa      240

uucgcgagga ugguacggua gggggcgcag ccgaccagag ucccgaaagc cuccugcagc      300

ugaaggcacu caaaccaggc gugauccaga uucugggggu caagacuucc agguucuugu      360

gucaacggcc cgauggugcc cuguacggca gccuccauuu ugacccagag gcgugcuccu      420

uccgcgagcu gcuguuggaa gauggguaua acguguacca gagugaggcc cacggccucc      480

cccugcaucu gccagguaau aaaagcccgc acagggaccc cgcaccacgg gggcccgccc      540

gcuuucuccc acugcccggc uugccgcccg cccugccaga acccccaggc auccucgcac      600

cccagccacc ggaugugggg uccagcgacc cccugaguau ggucggucca ucccagggca      660

ggagccccuc cuaugccagu ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  3246
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt7)

<400>  3246
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuuuccccc acugcuccug uugcuguucu ggggcguggu cucccauagu uucccggcca      120

cccucgagac ucaggaacaa gacguggauc ugguacagaa guacuuggag aaauauuaca      180

accugaagaa ugacgggagg caaguggaaa aacggcgcaa cagcgguccc gucguggaga      240

agcucaaaca gaugcaggaa uuuuucggcc ugaaggugac cgggaagcca gaugcagaga      300

cgcugaaagu caugaagcag cccaggugcg gcgugccaga cguagcccag uuugugcuca      360

cugaggguaa uccccggugg gaacagaccc accugaccua ucgcaucgag aacuacacuc      420

cagauuugcc gagggcggac gucgaucaug ccauugaaaa agcauuccaa cuguggucca      480

augugacgcc ccucaccuuu acuaagguga gugaggggca ggccgacauc augauuagcu      540

ucguccgggg cgaucaccgc gacaacuccc cauuugaugg ccccgggggu aaucuggcac      600

augccuucca gccaggcccc gggaucggcg gugacgcgca cuuugaugag gacgaaaggu      660

ggaccaacaa uuuccgggag uauaaccugc accgcguggc cgcacaugaa uuggggcaca      720

gccucggccu gucccauagu acugacauug gcgcccugau guacccgagc uauaccuucu      780

ccggggaugu acagcucgcc caagacgaua ucgacgguau ccaggcaauu uacggcagga      840

gccagaaucc cgugcaacca aucgggcccc agaccccaaa agccugugau aguaagcuga      900

cguuugacgc gauuacuacc auccggggcg aggucauguu cuuuaaagau cgcuucuaca      960

ugaggacuaa ccccuuuuau ccagaagugg aguugaauuu cauuuccgug uuuuggccgc     1020

agcugcccaa cggucucgag gccgcauacg aguucgccga ccgggaugaa guccgcuuuu     1080

ucaagggcaa uaaguauugg gcagugcagg ggcaaaacgu acugcacggc uacccaaaag     1140

acaucuauag cuccuuuggg uuccccagga ccgugaagca cauugaugcc gcccugagug     1200

aagagaacac cgguaaaacu uacuuuuucg ucgcgaauaa guauuggcgg uacgacgaau     1260

acaaacgcag cauggaccca ggcuauccca agaugaucgc acaugauuuc ccggggaucg     1320

gccacaaggu ggacgccguc uuuaugaaag augguuucuu uuacuucuuu cauggcacga     1380

ggcaguauaa guucgaccca aaaaccaagc ggauuuugac ucuccagaaa gccaacuccu     1440

gguuuaauug caggaagaac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  3247
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt7)

<400>  3247
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuuuccccc acugcuccug uugcuguucu ggggcguggu cucccauagu uucgugcuca      120

ccgaggggaa cccgaggugg gaacagacuc accugaccua ccggaucgag aauuauacgc      180

ccgacuugcc acgcgccgau guagaccaug caauugaaaa ggccuuucaa cuguggagca      240

acgugacucc ccucaccuuc accaaagucu ccgaggguca ggcggauauc augauuaguu      300

uugugagggg cgaccaccgg gauaauagcc cauucgacgg gcccggcggu aaccuggccc      360

augcauuuca gccagggccg ggcaucggcg gggaugccca cuucgacgaa gaugagcgcu      420

ggacuaauaa cuuuagggag uacaaucugc accggguggc agcccaugaa cucggucacu      480

cccugggcuu gagccauucc accgacauug gggcgcugau guaucccagu uacacguuca      540

gcggcgaugu ccagcucgcc caagacgaua ucgacgguau ccaggcaauu uaugggcgcu      600

cccagaaccc agugcagccc aucggcccac aaacucccaa ggccugcgac agcaaacuga      660

ccuuugaugc cauuacuacc aucaggggcg agguaauguu cuucaaggac cgguuuuaca      720

ugcgcaccaa uccguucuau cccgaagugg agcugaacuu uauuaguguc uucuggccac      780

aguugcccaa ugggcucgag gcagccuacg aauuugcgga uagggacgag gugcgguucu      840

uuaaagguaa caaguacugg gccgugcagg gccagaaugu ccugcacggg uauccaaagg      900

auaucuacuc cagcuucggc uuuccccgca cggugaaaca cauugacgca gcccuguccg      960

aagagaacac ugguaagacc uauuucuuug uagcaaauaa auacuggagg uaugaugaau     1020

acaagcggag uauggaccca ggcuauccga aaaugaucgc ccaugauuuc cccgggaucg     1080

gccacaaggu ggacgccguc uuuaugaaag auggguucuu cuacuuuuuc caugguacuc     1140

gccaauacaa guuugaccca aagaccaaaa ggauucucac ccugcagaag gcgaacagcu     1200

gguucaacug ucggaaaaau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  3248
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt7)

<400>  3248
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

aaaacauccu gaagauucuc auggacagcu acuccaaaga gaguaagauc cagaccguga      120

ggcgggucac uagcgugucc cuguuggccg uauaucugac caugaauacg aguagccucg      180

ugcuggcaaa acccauugaa aacacuaaug auaccuccau caagaacguc gagaaguugc      240

gcaaugcccc aaacgaagag aauagcaaaa agguggaaga cuccaaaaac gauaaggugg      300

agcacgucaa aaauauugag gaagcgaagg uggagcaagu agccccggaa gugaaaagua      360

agagcacccu gagguccgca agcaucgcca acacuaauag ugagaaguac gacuucgagu      420

aucucaacgg ccuguccuac accgaacuga cgaaucucau caaaaacauu aaguggaauc      480

agaucaacgg gcuguuuaac uauagcacug guucccagaa auucuuuggc gauaagaauc      540

ggguccaggc aauuaucaac gccuugcaag agagugggcg caccuacacu gcgaaugaca      600

ugaaaggcau ugaaaccuuc accgaggugc ugagggccgg uuuuuaucuc ggguacuaca      660

acgauggccu gagcuaucug aaugaccgga acuuccagga uaagugcauc cccgcaauga      720

uugccaucca gaagaaucca aacuuuaaau ugggcacggc cgugcaggac gaagucauca      780

cuucccucgg gaagcugauu gguaaugcaa gcgccaacgc ggagguggua aauaacugug      840

ugcccguccu gaaacaauuc cgcgagaauc ucaaccagua cgccccagau uaugugaagg      900

gcaccgcagu gaaugaacug aucaaaggga uugaguuuga cuucaguggc gccgcauacg      960

aaaaggaugu caagacuaug cccugguaug guaaaaucga cccauuuauu aacgaguuga     1020

aggcccuggg gcucuacggc aacaucaccu ccgccaccga augggcgagc gacgugggca     1080

ucuauuaccu gaguaaauuc gggcuguacu ccacuaauag gaacgauauu guacagagcu     1140

uggagaaggc aguggacaug uauaaauacg guaagaucgc cuucgucgcc auggagcgga     1200

uuacguggga uuaugacggc aucgggagca auggcaagaa aguggaucau gacaaguuuc     1260

ucgaugacgc agaaaaacac uaccugccga agaccuauac uuucgauaac gguaccuuua     1320

uuauccgcgc cggcgacaaa gucuccgagg aaaagaucaa aaggcuguac ugggcgaguc     1380

gggagguaaa gagccaguuc caucgcgugg uggggaauga uaaggcccuc gaagugggca     1440

acgcagacga cguccugacc augaaaauuu uuaauucccc cgaggaguau aaguucaaca     1500

cuaauaucaa cggggugagc acggauaaug guggcuugua cauugaacca agggggaccu     1560

uuuacacuua ugagcggacu ccccaacaga guaucuucuc ccuggaggaa cucuuucgcc     1620

acgaguacac ccauuaucug caggccaggu accuggucga cggcuugugg ggucaaggcc     1680

cauucuauga gaaaaaccgg cucaccuggu uugaugaagg gacggcagag uucuuugccg     1740

gcagcacccg cacuuccggg gugcugccca ggaagaguau ucugggcuac cucgccaaag     1800

acaaggugga ucaccgguau agccugaaga aaaccuugaa cuccgguuac gacgauagcg     1860

acuggauguu cuacaauuau ggguucgcag uagcccacua ccuguaugaa aaggauaugc     1920

cgacuuuuau caaaaugaau aaggcgauuc ucaacaccga cgugaaaagu uacgaugaaa     1980

ucaucaagaa gcuguccgac gaugccaaca aaaauacgga guaucagaac cauauucagg     2040

agcuggcaga caaguaccag ggcgccggua uccccuuggu cagcgacgau uaucugaaag     2100

accacggcua caagaaagcc uccgaagugu acagugagau uagcaaggca gcgucccuca     2160

ccaauacuag cgucaccgcc gagaaaaguc aauauuucaa cacuuuuacc cugaggggga     2220

cguacaccgg cgaaacuucc aagggggagu ucaaggauug ggacgaaaug agcaaaaagc     2280

ucgauggcac ccuggagucc uuggccaaaa auagcuggag ugguuauaag acucugaccg     2340

cauacuuuac gaacuaucgc gugaccagcg acaauaaagu gcaguacgau guagucuucc     2400

auggggugcu cacugacaac gccgauaucu ccaauaacaa ggcaccaauu gccaagguga     2460

ccggccccag uacuggcgcg gucgggcgga auaucgaauu uagcgguaaa gacuccaagg     2520

augaggacgg caaaaucgug agcuacgacu gggauuucgg ggacggcgcc accuccaggg     2580

guaagaacag ugugcacgca uauaaaaagg ccgggacgua caauguaacc cugaagguca     2640

cugaugacaa aggcgccacc gcaacugaga gcuuuaccau ugaaaucaag aacgaagaua     2700

cuaccacgcc aauuaccaaa gagauggagc ccaaugacga uaucaaggaa gccaacggcc     2760

caauugugga gggggugacu gucaaaggug accugaacgg cuccgaugac gcggauaccu     2820

ucuauuuuga cgugaaggaa gauggggacg uaacuaucga guugccguac aguggcagcu     2880

ccaauuucac cuggcuggug uauaaagagg gugacgauca gaaccacauc gccagcggga     2940

uugacaagaa uaacaguaag gucggcacgu ucaaauccac caagggccgc cauuacgugu     3000

uuaucuauaa acacgauagc gcauccaaua uuagcuacag ucucaacauc aaggggcugg     3060

guaaugaaaa acucaaggag aaggaaaaca augacuccag cgauaaagcc acugugauuc     3120

ccaacuucaa uaccacuaug cagggcaguc uguuggggga cgauucccgg gacuacuaua     3180

gcuuugaggu caaggaagag ggcgagguga acaucgaacu ggauaaaaag gacgaguucg     3240

guguaaccug gacgcugcau ccagaaucca auauuaacga uaggaucacc uacgggcaag     3300

uggacggcaa uaaagucagc aacaagguga agcuccgccc cggcaaauau uaccuguugg     3360

uguauaagua cagugggagc gguaacuaug agcugcgggu caauaaauga ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  3249
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt7)

<400>  3249
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuucugu ucuccagugc cuacagcauu gcaaacacua      120

auuccgagaa auaugacuuu gaauacuuga acggccugag uuauaccgag cucacgaauc      180

ugaucaagaa cauuaaaugg aaucagauca acggguuguu caauuacagc acugguuccc      240

aaaaguuuuu cggcgauaaa aacagggucc aggccauuau caaugcgcug caggaaagcg      300

ggcggaccua uaccgccaac gacaugaagg gcaucgagac uuuuaccgaa gugcuccgcg      360

cagguuucua ccugggguau uacaaugaug gccuguccua ccucaacgac aggaauuuuc      420

aggauaagug cauucccgcc augaucgcaa uucagaaaaa cccaaauuuc aagcugggca      480

cggccguaca ggacgaggug aucacuagcu uggggaaacu gauugguaac gcgagcgcca      540

acgcagaggu cgugaauaac ugugugccgg uccucaagca guuucgggaa aaucugaacc      600

aguaugcccc cgauuacgug aaaggcaccg ccguaaauga gcugaucaag gggauugagu      660

ucgacuucuc cggcgcagcc uaugaaaaag augugaagac uaugccaugg uacgguaaga      720

ucgaccccuu uaucaacgag uugaaagcgc ucgggcugua uggcaauauu accagcgcca      780

ccgaaugggc aagugauguc ggcaucuacu aucuguccaa guucgggcuc uacagcacga      840

accgcaauga cauugugcaa ucccuggaga aagccgugga uauguacaag uaugguaaaa      900

ucgcauuugu cgccauggaa aggauuacuu gggacuacga cggcaucggg aguaacggca      960

agaaggugga ucacgacaaa uucuuggaug acgccgagaa gcauuaucug ccaaaaaccu     1020

acacuuuuga uaaugguacc uucaucauuc gggcgggcga caagguaagc gaagagaaaa     1080

ucaagcgccu cuauugggca uccagggagg ugaagaguca guuucaccgg gucgugggga     1140

acgauaaagc ccuggaagug ggcaaugccg acgauguccu gaccaugaag auuuucaaca     1200

gucccgagga auacaaauuu aauacuaaca ucaacggggu guccacggac aaugguggcu     1260

uguauauuga gccacgcggg accuucuaca cuuacgaaag gaccccgcag cagagcaucu     1320

uuagucucga ggagcuguuc cggcaugaau auacccacua ccugcaagca cgcuaucucg     1380

uagauggccu guggggucag ggccccuuuu acgagaagaa cagguugacu ugguucgacg     1440

aagggacggc cgaguucuuu gcgggcucca cccggacuag cggggugcug ccacgcaaaa     1500

gcauccucgg cuaucuggcc aaggacaagg ucgaucauag guacucccug aaaaagaccu     1560

ugaauagugg uuaugacgau agcgacugga uguucuacaa cuacggguuu gcaguggccc     1620

acuaucucua cgaaaaagau augcccaccu ucauuaagau gaauaaagca auccugaaca     1680

cugacgucaa guccuaugau gagauuauca aaaagcugag cgacgaugcc aauaagaaca     1740

cggaguacca gaaucacauu caagaacucg ccgacaaaua ucagggcgca gguaucccac     1800

uggugaguga ugacuacuug aaggaucaug gcuauaaaaa ggccuccgag guguacagcg     1860

aaauuuccaa agcggccagu cugaccaaca cuagcguaac cgcagagaag ucccaguacu     1920

uuaauacuuu cacccuccgg gggacguaua ccggcgagac uagcaagggg gaauuuaaag     1980

acugggacga gaugaguaag aaacuggaug gcacccugga auccuuggcc aagaacagcu     2040

gguccgguua caaaacucug accgccuauu ucacgaauua ccgcgugacc agugacaaca     2100

agguccagua ugaugugguc uuucacgggg ugcucacuga caaugcagau aucagcaaca     2160

acaaggcgcc caucgccaaa gugaccggcc cguccacugg cgcaguaggg aggaauauug     2220

aguucagcgg uaaggacagu aaagaugaag acggcaagau cguguccuac gauugggacu     2280

uuggggaugg cgccaccagc cgggguaaaa acuccgucca ugccuacaag aaagcaggga     2340

cguauaaugu gacccugaag gucacugacg acaagggcgc caccgcgacu gagagcuuca     2400

ccauugagau caaaaacgaa gauacgacca cucccauuac caaggagaug gaaccaaaug     2460

acgauaucaa agaggccaac ggccccaucg uggaaggggu gacuguaaag ggugaccuca     2520

auggcaguga ugacgcagau accuucuacu uugacgucaa agaggauggg gacgugacua     2580

uugagcugcc auauagcggc uccaguaacu ucaccugguu gguguacaag gaaggugaug     2640

accaaaauca caucgccagc gggauugaua agaacaauuc caaagucggc acguuuaaga     2700

gcaccaaagg caggcacuau guguucaucu acaagcauga cuccgccagu aacauuagcu     2760

auucccugaa uaucaaaggg cucgguaacg agaagcugaa ggaaaaagag aauaacgaca     2820

guagcgauaa ggcaacugug auccccaacu uuaauaccac uaugcagggc ucccuguugg     2880

gggacgauag ccgcgacuac uacaguuucg aaguaaaaga ggagggcgaa gucaacauug     2940

agcuggauaa gaaagacgaa uuugguguga ccuggacgcu ccacccagag uccaauauca     3000

acgaucggau uaccuauggg caaguggacg gcaauaaggu cagcaacaaa gugaagcuga     3060

ggccgggcaa guacuaucuc cugguauaca aauauuccgg gagcgguaau uacgaguugc     3120

gcgugaacaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  3250
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt7)

<400>  3250
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuucugu ucuccagugc cuacagcaug aaaaagaaca      120

uuuugaaaau ccugauggac uccuauagua aggagagcaa aauucagacu gucaggcggg      180

ugaccuccgu aagccuccug gcaguguacu ugacgaugaa uacuuccagu cugguccucg      240

ccaagcccau cgaaaacacc aaugauacca gcauuaagaa cguggagaaa cugcgcaaug      300

cgccaaacga agaaaauucc aagaaagugg aagacagcaa gaacgauaaa gucgagcacg      360

ugaagaauau cgaggaagcc aaaguagagc aaguggcacc ggaagucaag aguaagucca      420

cucugaggag cgccucccgg cgcaggcgga aacgcaucgc aaacaccaau agugagaagu      480

augacuuuga guaccucaac ggccugagcu auacggaauu gacuaaucug auuaaaaaca      540

ucaaguggaa ucagauuaac ggucucuuca acuacuccac cgggagccag aaauuuuucg      600

gcgauaagaa uagggugcag gccaucauua acgcgcugca agagaguggg cggacuuaua      660

ccgccaauga caugaagggc aucgaaaccu uuacggaggu gcugcgcgca gguuucuacu      720

ugggguacua uaacgauggc cucuccuacc ugaaugacag gaacuuucag gauaaaugca      780

uucccgccau gaucgccauc cagaagaauc caaacuucaa acugggcacu gcaguccagg      840

acgaagugau uaccagccuc gggaagcuga ucgguaaugc cagugcgaac gccgagguag      900

ugaauaacug uguccccgug uugaaacaau uucgggagaa ucugaaccag uaugcaccag      960

auuacgugaa gggcacugcc gucaaugaac ucauuaaggg gaucgaguuc gacuucuccg     1020

gcgcagccua ugaaaaagau gugaagacca ugcccuggua cgguaaaauu gacccauuua     1080

ucaacgagcu gaaggcccug ggguuguaug gcaacaucac cagcgcgacu gaaugggcaa     1140

gcgacguagg cauuuacuac cucuccaaau ucgggcugua uaguacgaau cgcaacgaua     1200

ucgugcagag ccuggagaag gccgucgaca uguacaagua ugguaaaauu gccuuugugg     1260

caauggagag gaucaccugg gauuacgacg gcauuggguc caauggcaag aaagucgauc     1320

augacaaguu ccucgaugac gccgaaaaac acuaucugcc gaagacuuac accuuugaua     1380

acgguaccuu caucauccgg gcgggcgaca aagugagcga ggaaaagauu aagcgcuugu     1440

auugggccag uagggaggug aaaucccagu uucaucgggu aguggggaau gauaaggcac     1500

uggaagucgg caacgccgac gacgugcuca cuaugaaaau cuucaauagc cccgaggagu     1560

acaaguuuaa cacgaauauu aacggggucu ccaccgauaa ugguggccug uacaucgaac     1620

cacgcgggac uuucuauacc uacgagagga cuccccaaca gaguauuuuu agccuggaag     1680

aguuguuccg gcacgaguau acccauuacc uccaggcaag guaucuggug gacggccugu     1740

ggggucaagg cccauuuuac gagaaaaacc gccucacgug guucgaugag gggaccgccg     1800

aguucuuugc cggcuccacu cggaccagcg gggugcugcc caggaagagu aucuugggcu     1860

aucuggcaaa ggacaaagua gaucaccgcu acucccucaa gaaaacucug aauagcgguu     1920

acgacgauuc cgacuggaug uucuauaacu acggguuugc cguggcgcac uaucuguacg     1980

aaaaggauau gccgaccuuc auuaaaauga auaaggccau cuugaacacg gacgucaaga     2040

guuaugauga aaucauuaaa aagcugagcg acgaugcaaa caaaaauacc gaguaccaga     2100

accauaucca ggagcucgcc gacaaguauc agggcgccgg uauuccccug guguccgacg     2160

auuaccucaa agaccacggc uacaagaaag caagcgaagu cuauagugag aucuccaagg     2220

cggccagccu gacuaauacc uccgugacug cagaaaagag ccaauacuuu aacaccuuca     2280

cguugcgggg gaccuauacu ggcgagacca guaaagggga auuuaaggau ugggacgaga     2340

ugagcaaaaa gcuggauggc acucucgagu cccuggccaa aaauaguugg agcgguuaca     2400

agacccugac ggccuauuuc accaacuaca gggugacuuc cgacaauaag guacaguacg     2460

augucguguu ucauggggug uugaccgaca acgcagauau uagcaauaac aaagccccaa     2520

ucgcgaaggu cacuggcccc uccaccggcg ccguggggcg caauaucgag uucaguggua     2580

aagacagcaa ggaugaagac ggcaaaauug uguccuauga cugggauuuu ggggacggcg     2640

caacgagucg ggguaagaac agcguacacg ccuacaagaa agccgggacc uauaauguca     2700

cucugaaggu gaccgaugac aaaggcgcaa cugccaccga auccuucacu aucgagauua     2760

agaacgaaga uaccacgacc ccaaucacua aagagaugga gcccaaugac gauauuaagg     2820

aagcgaacgg cccaaucgug gaggggguca ccgugaaagg ugaccucaac ggcagcgaug     2880

acgccgauac uuucuacuuu gacguaaagg aagaugggga cgugaccauc gagcugccgu     2940

auaguggcuc cagcaauuuc acguggcucg ucuacaagga gggugacgau cagaaccaca     3000

uugcauccgg gaucgacaaa aauaacagca aggugggcac cuuuaaaagu acuaagggca     3060

ggcauuaugu guucauuuac aaacacgauu ccgccagcaa uaucaguuac ucccugaaca     3120

uuaagggguu ggguaaugaa aagcugaaag agaaggaaaa caaugacagc uccgauaaag     3180

caaccgucau ccccaacuuu aauacuacca ugcagggcag ccugcucggg gacgauaguc     3240

gggacuauua cagcuucgag gugaaggaag agggcgaggu aaacauugaa cuggauaaaa     3300

aggacgaguu uggugugacg uggaccuugc auccagaauc caauaucaac gaucgcauca     3360

cuuaugggca agucgacggc aauaagguga guaacaaagu gaagcugagg cccggcaaau     3420

acuaucuccu ggucuacaag uauagcgggu ccgguaacua cgagcuccgg gugaauaaau     3480

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  3251
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt7)

<400>  3251
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugaagau cauucucaau aggggcaaaa ccaugaagcg gaaaugccug agcaagcgcu      120

ugaugcuggc caucacuaug gcaaccauuu uuacggugaa cuccacucuc cccaucuacg      180

ccgcggucga caaaaauaac gccaccgcag ccgugcagaa ugagaguaag agguauaccg      240

uaagcuaccu gaagacuuug aacuauuacg aucuggugga ccuccugguc aaaaccgaaa      300

uugagaaucu gccagaucuc uuccaauauu ccagugacgc aaaggaauuu uacgggaaca      360

aaacgcggau gagcuucauc auggaugaga ucggucgcag ggccccgcag uauacugaaa      420

uugaccacaa gggcaucccc acccuggugg aggugguccg ggcgggguuu uacuugggcu      480

uccauaauaa agagcugaac gaaauuaaua agcgcuccuu uaaagagagg gugaucccaa      540

gcauucucgc cauccagaag aaccccaauu ucaagcuggg uacugaagua caggauaaaa      600

uuguguccgc aaccgggcug uuggccggca acgagaccgc cccacccgag gucgugaaua      660

acuuuacgcc aauccuccaa gacuguauca agaacauuga ucgguacgca cuggacgauc      720

ugaaaaguaa ggcccucuuc aaugugcugg cggccccgac uuaugacauc accgaauacu      780

ugcgcgcaac uaaagagaag cccgaaaaca ccccauggua uggcaagauu gauggguuua      840

ucaaugagcu gaaaaagcuc gcccuguacg guaaaauuaa cgacaauaac agcuggauca      900

ucgacaaugg cauuuaucac aucgcacccc uggggaaguu gcauuccaac aauaaaauug      960

gcaucgaaac ccucacugag gucaugaagg uguacccaua ucugagcaug cagcaucugc     1020

agagugccga ucagauuaag aggcacuacg acuccaaaga ugccgagggu aacaagaucc     1080

cccucgacaa auucaagaaa gaagggaagg agaaguacug cccgaaaacg uauaccuucg     1140

augacggcaa gguaaucauu aaagcgggcg cacgggugga agaggaaaag gucaaacgcc     1200

uguacugggc cagcaaggag gugaauaguc aauuuuucag gguguauggg aucgauaaac     1260

ccuuggagga agguaaccca gacgauauuc ugacuauggu caucuacaau agucccgagg     1320

aauauaagcu caacagcgug cuguacggcu augacaccaa uaacgggggc auguacauug     1380

agccagaagg uaccuuuuuc acuuacgagc gggaggccca ggaauccacg uauacccugg     1440

aggaauuguu ucgccacgag uacacucacu aucuccaggg cagguacgca guacccgggc     1500

aguggggccg gaccaagcug uaugauaacg accgccugac cugguacgag gaagggggug     1560

ccgaacucuu cgcgggcagc acuaggacga gugggauccu gccacggaaa uccauuguga     1620

gcaauaucca uaacaccacu aggaauaacc gcuauaaguu gagugacacc guccacucca     1680

aauacggcgc cagcuuugag uucuacaauu augcauguau guuuauggau uacauguaua     1740

acaaggacau ggguauccug aauaaacuca acgaucuggc caagaauaac gacguggaug     1800

gcuacgacaa uuauauucgg gaucugagcu ccaacuacgc auugaaugac aaguaucaag     1860

aucauaugca ggagaggauc gacaacuacg aaaaucugac ugucccguuc guggccgaug     1920

acuaccucgu gcgccacgcc uauaaaaacc ccaacgagau uuacagugag aucagcgaag     1980

uagcaaagcu gaaagaugcc aaguccgagg ugaaaaagag ccaguauuuu aguaccuuca     2040

cgcuccgggg guccuacacc ggcggggcga gcaagggcaa acuggaagac caaaaggcca     2100

ugaauaaauu uauugacgau uccuugaaga aacuggacac uuauaguugg agcgguuaca     2160

agacccucac ugcauacuuc accaacuaua aagucgauuc cagcaauagg gugacguacg     2220

acgucguguu ccacggguau cugccaaacg agggcgauag uaaaaauucc cugcccuacg     2280

guaagaucaa cggcaccuau aaggggacug aaaaggagaa aaucaaguuu agcuccgagg     2340

gcaguuucga cccagauggg aaaauuguga gcuacgaaug ggacuuuggc gaugguaaua     2400

aguccaacga ggaaaauccc gagcauagcu augacaaggu agggaccuac acugugaaau     2460

ugaaggucac cgaugacaaa ggcgaaaguu ccgugagcac gaccacugcc gagaucaagg     2520

accuguccga gaacaaacuc ccggucauuu acaugcacgu gccaaagagc ggcgcccuga     2580

aucagaaggu gguauucuau gggaaaggua ccuacgaucc cgacggcagu aucgcagggu     2640

aucaguggga uuuuggcgac gguagcgauu ucuccaguga acagaacccc agccaugucu     2700

acacuaagaa aggggaguau accgugacgc uccgcgugau ggacuccagc ggccaaaugu     2760

ccgaaaagac caugaaaauu aagaucacug auccagucua ccccaucggc accgagaaag     2820

agccaaauaa caguaaggaa acugcgagcg ggccgauugu gcccgguauc ccaguguccg     2880

gcaccauuga gaauacuucc gaccaggauu auuuuuacuu cgacguaauc acccccgggg     2940

aagucaagau ugauaucaac aaacugggcu acgguggggc cacgugggug guguaugacg     3000

agaacaauaa cgcagucagc uacgccaccg augacggcca gaauuugucc ggcaaguuua     3060

aagccgacaa gccagggcgg uauuacauuc accuguauau guucaacggu agcuacaugc     3120

ccuauaggau caauaucgaa ggcagugugg ggcggugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  3252
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt7)

<400>  3252
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

ggaaaugccu gagcaagcgg cucaugcugg ccaucaccau ggcaacuauu uucaccguga      120

acuccacguu gcccaucuac gccgcggucg acaaaaauaa cgccacugca gccgugcaga      180

augagaguaa gcgcuauacc guaagcuacc ugaaaacccu caacuauuac gaucuggugg      240

acuugcuggu caagacugaa auugagaauc ucccagaucu guuucaauau uccagugacg      300

caaaggaguu cuacggcaac aaaaccagga ugagcuuuau cauggaugaa auugggcggc      360

gcgccccgca guauacggaa aucgaccaca aggguauccc cacucuggug gaggugguca      420

gggcgggcuu cuaccucggg uuucauaaua aagagcugaa cgaaauuaau aagcgguccu      480

ucaaagagcg cgugauccca agcauuuugg ccauccagaa gaaccccaau uuuaaacugg      540

gcaccgaagu acaggauaag auuguguccg caacuggucu ccuggccggg aacgagaccg      600

ccccacccga ggucgugaau aacuucaccc caauccugca agacuguauu aagaauaucg      660

auagguacgc auuggacgau cucaaaagua aggcccuguu uaacgugcug gcggccccga      720

cguaugacau cacugaauac cuccgggcaa ccaaagagaa gcccgaaaac acuccauggu      780

auggcaaaau ugauggcuuc aucaaugagc ugaagaaguu ggcccuguac gggaaaauua      840

acgacaauaa cagcuggauc auugacaaug guaucuauca caucgcaccc cucggcaagc      900

ugcauuccaa caauaaaauu gggaucgaaa cccugaccga ggucaugaag guguacccau      960

auuugagcau gcagcaccuc cagagugccg aucagauuaa acgccauuac gacuccaagg     1020

augccgaggg caacaagauc ccccuggaca aauuuaagaa agaagguaag gagaaauacu     1080

gcccgaagac uuauacguuc gaugacggga agguaauuau caaagcgggc gcaagggugg     1140

aagaggaaaa ggucaaacgg cuguacuggg ccagcaagga ggugaauagu caauucuuuc     1200

gcguguaugg caucgauaaa ccccucgagg aagggaaccc agacgauauu cugaccaugg     1260

ucaucuacaa uagucccgag gaauauaagu ugaacagcgu gcuguacggu uaugacacua     1320

auaacggcgg gauguacauu gagccagaag gcaccuucuu uaccuacgag agggaggccc     1380

aggaauccac uuauacgcuc gaggaacugu uccggcacga guacacccac uaucugcagg     1440

gucgcuacgc aguacccggc caguggggga ggacuaaauu guaugauaau gaccggcuca     1500

ccugguacga ggaaggcggg gccgagcugu uugcggguag cacccgcacu uccggcaucc     1560

ugccaaggaa guccauugug agcaacaucc auaacacgac ccggaauaac agguauaagc     1620

ucagugacac uguccacucc aaauacgggg ccagcuucga auuuuacaau uaugcaugua     1680

uguucaugga uuacauguau aacaaggaca ugggcauucu gaauaaauug aacgaucugg     1740

ccaagaauaa cgacguggau gguuacgaca auuauauccg cgaucucagc uccaacuacg     1800

cacugaauga caaauaucaa gaucauaugc aggagcggau cgacaacuac gaaaaucuga     1860

ccgucccguu uguggccgau gacuacuugg ugaggcacgc cuauaagaac cccaaugaga     1920

uuuacaguga gaucagcgaa guagcaaagc ugaaagaugc caaguccgag gugaaaaaga     1980

gccaguauuu caguacuuuu acccuccgcg gcuccuacac gggcggcgcg agcaaaggga     2040

agcuggaaga ccaaaaggcc augaacaaau ucauugacga uucccucaag aaacuggaca     2100

ccuauaguug gagcggcuac aagacuuuga ccgcauacuu uacuaacuau aaagucgauu     2160

ccagcaaucg ggugaccuac gacgucgugu uccacgguua ucugccaaac gagggggaua     2220

guaaaaauuc ccuccccuac ggcaagauca acgguacgua uaagggcacc gaaaaggaga     2280

aaauuaaguu cagcuccgag gggaguuuug acccagaugg caaaaucgug agcuacgaau     2340

gggacuucgg ggauggcaau aaguccaacg aggaaaaucc cgagcauagc uaugacaaag     2400

uagguacuua caccgugaag cugaagguca cugaugacaa aggggaaagu uccgugagca     2460

ccacgaccgc cgagaucaag gaccuguccg agaacaaauu gccggucauu uacaugcacg     2520

ugccaaagag cggcgcccug aaucagaaag ugguauuuua uggcaagggg acuuacgauc     2580

ccgacgguag uaucgcaggc uaucaguggg auuucgggga cggcagcgau uuuuccagug     2640

aacagaaccc cagccauguc uacaccaaga aaggugagua uacugugacc cucaggguga     2700

uggacuccag cgggcaaaug uccgaaaaga cgaugaaaau uaagaucacc gauccagucu     2760

accccauugg cacugagaaa gagccaaaua acaguaagga aaccgcgagc ggcccgaucg     2820

ugcccgggau cccagugucc gguacuauug agaauaccag ugaccaggau uauuucuacu     2880

uugacguaau cacucccggc gaagucaaaa uugauaucaa caagcugggg uacggcggug     2940

ccaccugggu gguguaugac gagaauaaca acgcagucag cuacgccacg gaugacgggc     3000

agaaucucuc cggcaaguuc aaagccgaca agccaggccg cuauuacauu caccuguaua     3060

uguuuaacgg gagcuacaug cccuaucgga ucaauauuga agguagugug gggaggugag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  3253
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt7)

<400>  3253
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuucugu ucuccagugc cuacagcguc cagaacgagu      120

ccaaaaggua uacugugagu uacuugaaga cccugaauua uuacgaccuc guagaucugu      180

uggugaaaac ggaaauugag aaccugcccg accucuuuca auauagcucc gaugcaaagg      240

aguucuacgg caauaaaacu cggaugagcu uuaucaugga cgaaauuggg cgcagggccc      300

cacaguauac cgaaaucgau cacaagggua uuccgacccu ggucgaggug gugcgggcgg      360

gcuucuaccu gggguuucau aacaaggagc ucaaugaaau caacaaacgc uccuucaagg      420

agagggucau ccccaguauu cuggccaucc agaaaaaucc aaacuuuaag uugggcacug      480

aagugcagga caaaauugua agcgcaaccg gucugcucgc cgggaaugag acggcacccc      540

cagagguggu caacaauuuc acucccaucc ugcaagauug cauuaagaac aucgaccggu      600

acgcccugga ugacuugaaa uccaaggcgc ucuuuaaugu gcuggccgca ccaaccuaug      660

auauuacuga auaccugcgc gccaccaagg agaaaccgga aaacaccccc ugguauggca      720

agaucgacgg cuucaucaau gagcucaaaa agcuggccuu guacgggaaa auuaacgaua      780

acaauagcug gaucauugac aacgguaucu aucacauugc accacugggc aagcuccaua      840

guaauaacaa gaucgggauc gaaacgcuga cugaggugau gaaagucuac cccuaucugu      900

ccaugcagca cuugcagagc gccgaccaga uuaagaggca uuacgauucc aaagacgcgg      960

agggcaauaa gaucccacuc gauaaauuca agaaggaagg uaaagagaag uacuguccca     1020

aaaccuauac uuuugacgau gggaagguga uuaucaaagc cggcgcacgg guagaagagg     1080

aaaaggugaa gcgccuguac ugggccagua aagaggucaa cagccaauuc uuuagggugu     1140

auggcauuga caagccgcug gaggaaggga aucccgauga cauccucacc auggugaucu     1200

acaacucccc agaggaauau aaacugaaua gcgucuugua cgguuaugau accaacaaug     1260

gcgggaugua cauugagccc gaaggcacuu ucuuuacgua cgagcgggag gcacaggaaa     1320

guaccuauac ucuggaggaa cucuuccgcc acgaguacac ccacuaucug caggguaggu     1380

acgccgugcc aggccagugg gggcggacca agcuguauga caacgaucgc uugacuuggu     1440

acgaggaagg cggggccgag cucuuugcgg guuccacgag gaccagcggc auccugcccc     1500

ggaaaaguau uguauccaau auccauaaca cuacccgcaa uaacagguau aagcugagcg     1560

acaccgugca cagcaaauac ggggcauccu ucgaauuuua caacuaugcc ugcauguuca     1620

uggacuacau guauaauaag gauaugggca uucucaacaa gcugaaugac uuggccaaaa     1680

acaaugaugu cgacgguuac gauaacuaua uccgggaccu gaguagcaau uacgcacuca     1740

acgauaagua ucaagaccau augcaggaga ggauugauaa uuacgaaaac cugacugugc     1800

cauuugucgc cgacgauuac cuggugcgcc acgcguauaa aaauccgaac gagaucuacu     1860

ccgagaucag cgaaguggcc aaguugaaag acgcaaagag ugagguaaag aaaucccagu     1920

auuucagcac guuuacccug cggggcuccu acacuggggg cgccaguaag gggaaacucg     1980

aagaucaaaa ggcaaugaau aaauucauug acgacagccu gaagaagcuc gauaccuauu     2040

ccuggagcgg cuacaaaacu cugaccgccu acuucacgaa cuauaaggug gacaguucca     2100

auagggucac cuacgaugug gucuuucacg guuauuugcc caacgagggg gacagcaaaa     2160

acucccugcc auacggcaag aucaauggua cuuauaaagg caccgaaaag gagaaaauua     2220

aguucaguag cgaggggucc uuugaucccg acggcaagau cgugagcuac gaaugggauu     2280

ucggggacgg caacaaaagu aaugaggaaa acccagagca uuccuaugau aaggugggua     2340

cuuacaccgu aaaacucaag gugacggacg auaaagggga aagcuccguc agcaccacua     2400

ccgccgagau uaaggaccug agugagaaua agcugcccgu gaucuacaug cacgucccga     2460

aaagcggcgc auugaaccag aagguggugu uuuauggcaa agggacuuac gacccagaug     2520

guuccaucgc cggcuaucag ugggacuucg gggauggcag ugacuuuagc uccgaacaga     2580

aucccagcca uguauacacc aagaaaggug aguauacggu cacccugcgc gugauggauu     2640

ccagugggca aaugagcgaa aagacuauga agauuaaaau caccgacccc guguacccaa     2700

uuggcacuga gaaggagccc aacaauucca aagaaaccgc gaguggccca aucgucccgg     2760

ggauucccgu gagcgguacg aucgagaaca ccuccgauca ggacuauuuc uacuuugaug     2820

ugaucacucc aggcgaagua aagauugaca ucaauaaacu cggguacggc ggugccaccu     2880

gggucgugua ugaugagaac aauaacgcag ugagcuacgc cacugacgau gggcagaauc     2940

ugaguggcaa guucaaagcc gacaagcccg gccgguauua cauucaccuc uauauguuua     3000

acggguccua caugccauau aggaucaaca uugaagguag cgucggccgc ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3254
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt7)

<400>  3254
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cucuuucugu ucuccagugc cuacagcaug aaaaggaagu      120

gcuuguccaa acggcugaug cucgcaauua cuauggccac caucuuuacg gucaacagua      180

cucugcccau uuaugcggcc guggacaaga auaacgcaac cgccgcacgc aggcggcgca      240

aaaggguaca gaaugagagc aagcgguaca ccguguccua uuugaagacu cugaacuacu      300

augaucucgu cgaccugcug gugaaaaccg aaaucgagaa ucucccagau cuguuccaau      360

acagcuccga cgccaaggaa uuuuauggca acaaaacgcg caugaguuuc auuauggaug      420

agaucgggag gcgggcgccg caguacacug aaaucgacca caaggguauu cccaccuugg      480

uggaggucgu gcgcgccggc uuuuaccugg gguuccauaa uaaagagcuc aacgaaauca      540

auaagaggag cuuuaaagag cggguaauuc cauccauccu ggcaauucag aagaacccca      600

auuucaagcu gggcacugaa gugcaggaua aaaucgucag cgccaccggu uugcucgccg      660

ggaacgagac cgcaccaccc gaggugguga auaacuuuac gccaauucug caagacugua      720

ucaagaauau cgaucgcuau gcccuggacg aucucaaaag uaaggcgcug uucaacgucu      780

uggccgcacc gacuuacgac auuaccgaau aucugagggc cacuaaagag aagcccgaaa      840

acaccccaug guacggcaag aucgauggcu ucauuaauga gcucaaaaag cuggcacugu      900

augggaaaau caacgacaau aacuccugga uuaucgacaa ugguaucuac cacauugccc      960

ccuugggcaa gcuccauagc aacaauaaaa ucgggauuga aacccugacu gaggugauga     1020

agguauaucc auaccugucc augcagcacc uccagagugc cgaucagauc aagcggcauu     1080

acgacagcaa agaugcggag ggcaacaaga uuccccugga caaauuuaag aaagaaggua     1140

aggagaagua uugcccgaaa acguacaccu ucgaugacgg gaaggugauc aucaaagcag     1200

gcgcccgcgu cgaagaggaa aaggugaaaa gguuguauug ggccuccaag gaggugaaua     1260

gccaauuuuu ccgggucuac ggcauugaua aaccccugga ggaagggaac ccagacgaua     1320

uccucacuau ggugauuuau aauagucccg aggaauacaa gcugaacucc guacuguaug     1380

guuacgacac caauaacggc gggauguaca ucgagccaga aggcaccuuu uucacuuaug     1440

agcgcgaggc acaggaaagc acguacaccu uggaggaacu cuuuaggcac gaguauacuc     1500

acuaccugca gggucgguau gccgugcccg gccagugggg gaggaccaag cuguacgaua     1560

augaccgccu caccugguau gaggaaggcg gggcggagcu guucgccggu aguacucgga     1620

cguccggcau uuugccaagg aaaagcaucg ucagcaacau ucauaacacc acucgcaaua     1680

accgguacaa gcuguccgac accgugcaca guaaauacgg ggcgagcuuu gaguucuaua     1740

auuacgccug uauguuuaug gauuauaugu acaacaagga caugggcauc cucaauaaac     1800

ugaacgaucu ggcaaagaau aacgacgucg augguuauga caauuacauc agggauuugu     1860

ccagcaacua ugcccugaau gacaaguacc aagaucauau gcaggaacgc auugacaacu     1920

acgaaaaucu cacugugccg uucguggccg augacuaucu gguacggcac gcauacaaaa     1980

accccaauga gaucuauagu gagauuuccg aaguggccaa gcucaaagau gcaaagagcg     2040

aggucaaaaa gucccaguac uuuaguaccu ucacgcugag gggcagcuau accgggggcg     2100

ccuccaaggg gaaauuggaa gaccaaaagg caaugaacaa auucaucgac gauagccuga     2160

agaaacucga cacuuacagu ugguccggcu acaagacccu gacugccuau uuuaccaacu     2220

acaaagugga uagcuccaau cgggucacgu augacguggu guuccacggu uaccugccaa     2280

acgaggggga uaguaagaau agcuugcccu auggcaagau uaacgguacc uacaaaggca     2340

cugaaaagga gaaaaucaag uuuuccagcg aggggaguuu cgacccagau ggcaaaaucg     2400

uauccuauga augggacuuu ggggauggca auaagagcaa cgaggaaaau cccgagcauu     2460

ccuacgacaa gguggguacc uacacuguca aacugaaggu gaccgaugac aaaggggaaa     2520

gcagugucag cacgaccacu gccgagauua aggaccucuc cgagaacaaa cugccgguga     2580

ucuauaugca cgugccaaag aguggcgcac ucaaucagaa gguagucuuc uacggcaaag     2640

ggaccuauga ucccgacggu agcauugcgg gcuaccagug ggauuuuggg gacggcuccg     2700

auuucagcuc cgaacagaac cccagucaug uguauacuaa gaaaggugag uacaccguga     2760

cgcugcgcgu cauggacagc uccgggcaaa ugagugaaaa gaccaugaaa aucaagauua     2820

cugauccagu guaucccauc ggcaccgaga aagagccaaa uaacagcaag gaaacugccu     2880

ccggcccgau cgugcccggg auuccaguaa gcgguaccau cgagaauacc agugaccagg     2940

auuacuuuua cuucgacguc auuacucccg gcgaagugaa gaucgauauu aacaaauugg     3000

gguauggcgg ugcaacgugg guggucuacg acgagaauaa caacgccgug uccuaugcca     3060

ccgaugacgg gcagaaucug agcggcaagu uuaaagcaga caagccaggc agguacuaua     3120

uccaccugua cauguucaac ggguccuaua ugcccuaccg gauuaauauc gaagguagcg     3180

uaggccgcug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  3255
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt7)

<400>  3255
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg cagccuuugc gaugcccuug ccaccgcacc      120

ccggucaucc aggcuacauu aacuucagcu augaggugcu gacuccccuc aagugguacc      180

aguccaucag gccacccuau ccaaguuacg gguaugaacc gaugggcggu uggcugcacc      240

aucaaauuau ccccgucuug agccagcagc acccacccac ccauacgcug cagccacacc      300

accauauucc cgugguaccg gcccaacagc ccgugauccc acagcagccc augaugccag      360

uccccgggca acacuccaug acuccaaucc agcaucacca gccgaaucug cccccacccg      420

cacagcaacc auaccagccc cagccggugc aaccacagcc ccaccagccc augcagccac      480

aacccccagu gcauccgaug cagccccucc caccccagcc accccugccg ccaauguuuc      540

ccaugcagcc acugcccccg augcuccccg acuugacccu ggaggccugg ccaaguaccg      600

auaaaacuaa gcgggaagag gucgacugag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  3256
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt7)

<400>  3256
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccaccgca ccccggccau ccaggguaca ucaacuucag cuaugaggug cucaccccac      120

ugaaguggua ccaguccauu aggccacccu aucccaguua cgguuaugaa ccgaugggcg      180

gguggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  3257
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt7)

<400>  3257
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccaccgca ccccggccau ccaggguaca ucaacuucag cuaugaggug cucacucccc      120

ugaaguggua ccaguccauu aggccacccc caauguugcc ggaccugacc cucgaagccu      180

ggcccaguac cgauaaaacg aagcgggagg aagucgacug aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  3258
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt7)

<400>  3258
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcacc caggacccug guccuccugu ugagcggcgc ccuggcgcuc acucagaccu      120

gggccaugcc acugccgccc cacccagggc aucccgguua caucaacuuc uccuaugagg      180

uguugacgcc acugaagugg uaccaaagua uucggccccc auauccgagc uacggcuaug      240

aacccauggg cgggugguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  3259
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt7)

<400>  3259
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcacc caggacccug guccuccugu ugagcggcgc ccuggcgcuc acucagaccu      120

gggccaugcc acugccgccc cacccagggc aucccgguua caucaacuuc uccuaugagg      180

uguugacgcc acugaagugg uaccaaagua uucggccccc accgaugcuc cccgaccuga      240

cucuggaagc auggccaagc accgauaaaa ccaagcgcga ggaaguagac ugaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  3260
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt7)

<400>  3260
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cucguggggg cagccuuugc gaugccccug ccaccgcacc      120

ccggucaucc aggcuacauu aacuucagcu augaggucuu gacuccccug aagugguacc      180

aguccaugau caggccaccc uauaguagcu acggguauga accaaugggc gguuggcucc      240

accaucaaau uaucccggug guaucccagc agcacccccu gacccauacg uugcagaguc      300

accaccauau uccagugguc cccgcccaac agccacgggu gcgccagcag gcacugaugc      360

ccgugccggg gcaacagagc augacuccca cccagcacca ucagccaaau cucccccugc      420

cagcccaaca gcccuuucag ccacaaccgg uccagcccca gccacaccag cccaugcaac      480

cacagccccc ggugcagcca augcagcccc ugcuccccca accaccccug ccaccgaugu      540

uccccuugag gccacugccc ccaauccucc ccgaccugca ccuggaggca uggccggcca      600

ccgauaaaac uaagcaggaa gagguagacu gaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  3261
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt7)

<400>  3261
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccaccgca ccccggccau ccaggguaca ucaacuucag cuaugaggug cucaccccac      120

ugaaguggua ccaguccaug auuaggccac ccuauaguag cuacgguuau gaacccaugg      180

gcggguggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3262
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt7)

<400>  3262
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccaccgca ccccggccau ccaggguaca ucaacuucag cuaugaggug cucacucccc      120

ugaaguggua ccaguccaug auuaggccac ccccaaucuu gccggaccug caccucgaag      180

ccuggcccgc aaccgauaaa accaagcaag aggaagucga cugaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3263
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt7)

<400>  3263
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcacc caggacccug guccuccugu ugagcggcgc ccuggcgcuc acucagaccu      120

gggccaugcc acugccgccc cacccagggc aucccgguua caucaacuuc uccuaugagg      180

uguugacgcc acugaagugg uaccaaagua ugauucggcc cccauauagc uccuacggcu      240

augaaccgau gggcgggugg ugaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3264
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt7)

<400>  3264
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcacc caggacccug guccuccugu ugagcggcgc ccuggcgcuc acucagaccu      120

gggccaugcc acugccgccc cacccagggc aucccgguua caucaacuuc uccuaugagg      180

uguugacgcc acugaagugg uaccaaagua ugauucggcc cccaccgauc cuccccgacc      240

ugcaccugga agcauggcca gccacugaua aaaccaagca ggaggaagua gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3265
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt7)

<400>  3265
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg cagccuuuag caugcccuug ccaccgcacc      120

ccggucaucc aggcuacauu aacuucuccu augaggugcu gacuccccuc aagugguacc      180

agaauaugau caggcaccca uauaccaguu acggguauga acccaugggc gguuggcugc      240

aucaccaaau uaucccaguc gugagccagc agacgccgca gucccaugcg uugcaacccc      300

accaccauau uccaauggua cccgcccagc agccagggau cccccagcaa ccgaugaugc      360

cccugccagg ccagcacagu augacuccca cccagcauca ccagccaaac cucccccugc      420

cagcacaaca gccguuucag ccccaaccag ugcagcccca gccacaccag ccccugcaac      480

cgcagagccc aaugcauccc auccagcccc uccugccaca gcccccauug ccgcccaugu      540

ucuccaugca aagccugcuc ccagaccugc cccuggaggc cuggccagca accgauaaaa      600

cuaagcggga agaggucgac ugaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3266
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt7)

<400>  3266
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccaccgca ccccggccau ccaggguaca ucaacuucag cuaugaggug cucacucccc      120

ugaaguggua ccagaauaug auuaggcacc cauauaccuc cuacgguuau gaacccaugg      180

gcggguggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3267
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt7)

<400>  3267
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccaccgca ccccggccau ccaggguaca ucaacuucag cuaugaggug cucacucccc      120

ugaaguggua ccagaauaug auuaggcacc cauccuugcu gcccgaccuc ccacuggaag      180

ccuggccggc aaccgauaaa accaagcggg aggaagucga cugaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3268
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt7)

<400>  3268
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcacc caggacucug guccuccugu ugagcggcgc ccuggcgcuc acucagaccu      120

gggccaugcc acugccgccc cacccagggc aucccgguua caucaacuuc uccuaugagg      180

uguugacgcc acugaagugg uaccaaaaua ugauucggca ccccuauacc aguuacggcu      240

augaaccaau gggcgggugg ugaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3269
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt7)

<400>  3269
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ugauggcacc caggacccug guccuccugu ugagcggcgc ccuggcgcuc acucagaccu      120

gggccaugcc acugccgccc cacccagggc aucccgguua caucaacuuc uccuaugagg      180

uguugacgcc acugaagugg uaccaaaaua ugauucggca ccccagucuc cugccagacc      240

ugccgcucga agcauggccc gccacugaua aaaccaagcg cgaggaagua gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3270
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt7)

<400>  3270
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg cagccuuuag caugcccuug ccaccgcacc      120

ccggucaucc aggcuacauu aacuucuccu auaucaggca ccccuacacc aguuaugggu      180

acgagccaau gggcgguugg cugcaucacc agauuauccc cguggucagc caacagacuc      240

cacaguccca ugcgcuccag ccgcaccacc auauucccau ggugccagcc caacagcccg      300

ggaucccaca gcagcccaug augccgcugc ccggccaaca caguaugacg ccaacucagc      360

aucaccagcc caauuugcca cugcccgcac agcaaccauu ucagccgcag cccguacaac      420

cacagcccca ccagccacuc cagccccaaa gcccgaugca uccaauccag ccccugcugc      480

cccagccacc ccucccaccg auguucucca ugcagagccu guugcccgac cugccacucg      540

aagccuggcc cgcaaccgau aagaccaaac gggaggaagu ggacugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  3271
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt7)

<400>  3271
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggaucuu cuuugccugc cugcucgggg caagccuggc caugcccuug ccaccgcacc      120

ccggucaucc aggcuacauu aacuucuccu augaggugcu gacuccccuc aagugguacc      180

agaauaugau caggcaccca uauaccaguu acggguauga acccaugggc gguuggcugc      240

aucaccaaau uaucccaguc gugagccagc agacgccgca gucccaugcg uugcaacccc      300

accaccauau uccaauggua cccgcccagc agccagggau cccccagcaa ccgaugaugc      360

cccugccagg ccagcacagu augacuccca cccagcauca ccagccaaac cucccccugc      420

cagcacaaca gccguuucag ccccaaccag ugcagcccca gccacaccag ccccugcaac      480

cgcagagccc aaugcauccc auccagcccc uccugccaca gcccccauug ccgcccaugu      540

ucuccaugca aagccugcuc ccagaccugc cccuggaggc cuggccagca accgauaaaa      600

cuaagcggga agaggucgac ugaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3272
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt7)

<400>  3272
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg cagccuuuag caugcccuug ccaccgcacc      120

ccggucaucc aggcuacauu aacuucuccu augaggugcu gacuccccuc aagugguacc      180

agaauaugau caggcaccca agucuguugc ccgaccugcc acucgaagcg uggccggcca      240

ccgauaaaac gaagcgggag gaagucgacu gaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  3273
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt7)

<400>  3273
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg cagccuuuag caugcccuug ccaccgcacc      120

ccggucaucc aggcuacauu aacuucuccu augaggaccu guaccucgaa gcgaucagga      180

uugaucggac ugccuuugug cugacccccu ugaaguggua ucagaauaug auccgccacc      240

cauacacgag uuauggguac gagcccaugg gcgguuggcu gcaucaccaa auuaucccag      300

ucgugagcca gcagacuccg cagucccaug cacuccaacc ccaccaccau aucccaaugg      360

uacccgccca gcagccaggg auuccccagc aaccgaugau gccccugcca ggccagcaca      420

guaugacccc cacccagcau caccagccaa accugccccu cccagcacaa cagccguucc      480

agccccaacc agugcagccc cagccacacc agccccugca accgcagagc ccaaugcauc      540

ccauccagcc cuugcugcca cagcccccac ucccgcccau guuuuccaug caaagccugc      600

ugccagacuu gccccucgaa gccuggccag cgacugauaa aaccaagagg gaggaagucg      660

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  3274
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt7)

<400>  3274
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu guucgccugc cuccuggggg cagccuuuag caugcccuug ccaccgcacc      120

ccggucaucc aggcuacauu aacuucuccu augaggugcu gacuccccuc aagugguacc      180

agaauaugau caggcaccca acgccccaaa gucaugcgcu gcagccacac caucacauuc      240

cgaugguccc cgcccagcag ccagggaucc cccaacagcc aaugaugccc uugccgggcc      300

agcacagcau gacccccacu cagcaucacc aaccaaaccu gccccuccca gcacagcagc      360

ccuuucagcc acaaccggug cagccccagc cacaucaacc ccugcagcca caguccccca      420

ugcacccgau ucagccacug cucccccaac ccccacugcc cccaauguuc aguaugcaga      480

gcuugcugcc ggaccucccc cuggaagccu ggccagcaac cgauaaaacc aagcgggagg      540

aaguagacug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  3275
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt7)

<400>  3275
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugccaccgca ccccggccau ccaggguaca ucaacuucag cuaugaggug cucacucccc      120

ugaaguggua ccagaauaug auuaggcacc cauauaccuc cuacgguuau gaacccaugg      180

gcgggugguu gcaucaccaa aucauuccag ucgugaguca gcagaccccg cagagccaug      240

cccugcaacc ccaccaccau aucccaaugg uacccgcaca gcagccaggc auuccccagc      300

aaccgaugau gccccuccca ggucagcacu ccaugacgcc cacucagcau caccagccaa      360

accugcccuu gccagcccaa cagccguuuc agccccaacc agugcagccc cagccacacc      420

agccccugca accgcagagu ccaaugcauc ccauccagcc ccuccugcca cagcccccac      480

ugccgcccau guucagcaug caaucccucc ugccagacuu gccccuggag gcguggccag      540

ccaccgauaa aaccaagcgg gaagaggucg acugaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  3276
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt7)

<400>  3276
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gcguggccag gcugccacuc cuguuggggc ugcuccuguu gccgcggccc ggucgcccac      120

uggaccucgc agauuacacc uaugaccugg ccgaggaaga ugacagcgag ccccugaacu      180

acaaggaucc augcaaagcg gccgcauucc ucggcgacau cgcccuggau gaagaggacu      240

ugagggcauu ucagguccaa caggccgugg aucugcggcg ccacacugcg aggaagucca      300

guauuaaagc cgcaguaccc gggaauacca gcacgccauc cugucagagu acuaacggcc      360

agccgcaacg gggugccugc gggcgcugga ggggccggag ccgcuccagg cgggccgcaa      420

ccagccgccc cgaaagggug uggccagacg gcgucauccc cuucgugauu ggggguaauu      480

uuaccggcuc ccagcgggcc guguuccgcc aggcgaugag gcauugggag aagcacacuu      540

gugucaccuu ucucgagcgg acggaugaag acaguuauau cguguucacu uaccgcccau      600

gcggguguug cagcuaugua ggcaggcggg gugggggccc ccaggccauu uccaucggca      660

aaaacuguga uaaguuuggg aucguggucc augagcuggg ucacguggug ggcuucuggc      720

augaacacac caggccggac cgcgaccggc acgucagcau ugugagggag aauauccaac      780

ccgggcagga guacaacuuu cugaagaugg aaccacagga gguagaaagu uugggcgaga      840

cuuaugauuu cgacuccauu augcauuacg cacgcaauac cuuuagccgg gguaucuucc      900

ucgauaccau ugugcccaaa uacgaaguca acggcgugaa gccacccauc gggcagagga      960

cgcgccuguc caaaggcgac auugcccaag cacggaagcu guauaaaugc ccagccugug     1020

gggagacucu ccaggauagu accgguaauu ucagcucccc ggaguacccc aacggcuaua     1080

gcgcccacau gcauugcgug uggaggauca gugucacucc aggggaaaag aucauucuga     1140

auuuuaccuc cuuggaccug uaccggagcc gccucugcug guaugauuac guggagguaa     1200

gggacggcuu cuggcggaaa gcgccccugc gcgguagguu uuguggcagu aagcugccag     1260

aacccaucgu guccaccgau agccgguugu gggucgaguu ccgcagcucc aguaacuggg     1320

uggggaaggg cuuuuucgca gucuaugaag ccauuugcgg gggcgacgug aaaaaggauu     1380

acggucacau ccagagcccg aauuacccag acgacuauag gcccuccaaa guguguauuu     1440

ggcggaucca aguaagcgag ggguuucacg ugggccucac uuuccagagu uuugagaucg     1500

aaaggcauga uuccugcgcc uacgacuauc uggagguccg cgauggucac agcgaaucca     1560

guacgcugau uggccgguac uguggguaug agaagcccga cgauaucaaa agcaccucca     1620

gcaggcucug gcugaaguuc gugagugacg gcuccauuaa caaggcaggg uuugccguca     1680

auuucuuuaa agaaguggau gagugcagcc gcccaaaccg gggcgguugu gagcagaggu     1740

gcuugaacac ucuggggucc uacaagugua guugcgaccc cggcuaugaa cucgcgccag     1800

auaaacgccg gugcgaggcc gcauguggcg gguuccugac caagcugaau gguagcauca     1860

ccuccccggg cuggcccaaa gaauacccac ccaacaagaa uugcauuugg caguuggugg     1920

ccccaacuca auacaggauc agccuccagu ucgacuuuuu cgagacggag gggaacgaug     1980

uauguaagua ugacuuugug gaaguccgca guggccugac cgcagauucc aaacugcaug     2040

guaaguucug cgggagcgag aaacccgaag ugaucacuuc ccaguacaau aacaugcggg     2100

ucgaguuuaa gagcgacaau accgugagua aaaagggcuu caaggcccac uuuuucagcg     2160

acaaagauga auguuccaag gacaacggcg ggugccagca agauugugug aauaccuuug     2220

guaguuauga gugccagugu aggagcggcu ucguacucca ugacaacaaa cacgauugca     2280

aggaggccgg gugugaccac aaagucacuu ccacgagcgg caccauuacu uccccgaauu     2340

ggccagauaa guaccccagu aaaaaggaau gcaccugggc aaucagcucc acuccagguc     2400

aucgcgugaa gcugaccuuu auggagaugg acauugaaag ucagcccgag ugcgccuaug     2460

aucacuugga aguguucgac gggcgggaug cgaaagcccc gguccugggc agguucugug     2520

gcagcaagaa acccgagcca gugcucgcaa cggggucccg cauguuucug cgguucuaca     2580

gcgacaacag ugugcagagg aaggguuuuc aagccuccca ugccaccgag ugcggcgggc     2640

agguacgcgc agacgucaaa acuaaggauc uguauagcca cgcgcaguuc ggcgacaaua     2700

acuaccccgg ugggguggau ugugaauggg ugaucgucgc cgaggaaggc uacggcgugg     2760

aguugguauu ucagaccuuc gaaguggagg aggaaacuga cugcggguau gauuacaugg     2820

agcuguuuga cgguuaugau uccaccgcac caaggcucgg ccgguacugu gggagcgguc     2880

ccccagaaga ggucuauagu gccggcgacu ccgugcuggu gaaguuccac agcgaugaca     2940

cgauuaccaa aaagggcuuu caucucaggu acaccaguac uaaauuccaa gauacucugc     3000

acucccgcaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  3277
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt7)

<400>  3277
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

ccggcaccag gugccugcuc gcacuguugc ugccccaggu ccuccugggu ggggccgcgg      120

gcuuggugcc agagcugggg cggcgcaagu ucgccgcagc cagcuccggc aggccgagua      180

gccaacccuc cgacgaagua cucagugagu uugaacugcg gcugcucagc auguucgguc      240

ugaaacagcg cccaacuccc uccagggaug cagugguccc acccuacaug uuggaccugu      300

aucggcgcca cagcgggcag ccaggcuccc cggcccccga ucauaggcuc gagcgggcgg      360

ccagucgcgc aaacaccgug aggagcuuuc accaugaaga gucccuggag gaacugccag      420

agacgagcgg caagacuacc cggcgcuucu uuuucaauuu gaguuccauc cccaccgaag      480

aguuuauuac uagcgccgag cuccaggugu ucagggaaca aaugcaggac gcccugggga      540

acaauuccag uuuucaccau cggaucaaca uuuacgagau cauuaaacca gcaaccgcca      600

auagcaaguu ccccgucacg cgccugcucg auacuaggcu ggugaaccag aaugcguccc      660

ggugggaauc cuuugacgua accccggccg ugaugcgcug gacugcacag ggucacgcca      720

accacggcuu cgucguggag guggcacauu uggaagagaa acaagggguc aguaagaggc      780

acgugcggau cuccaggagc cugcaucagg augagcacag uuggucccag auccgccccc      840

uccugguaac cuucggccac gacgguaagg ggcauccacu gcacaaacgg gaaaagaggc      900

aggccaaaca uaagcaacgc aaacggcuca agagcagcug uaaaaggcac cccuuguaug      960

uggauuuuuc cgacgucggc uggaaugauu ggauuguggc cccacccggc uaccaugcgu     1020

ucuauugcca cggggagugu ccauuuccgc uggcagacca ccugaacagu accaaucaug     1080

ccaucgugca gacgcucguc aacagcguga auagcaagau ucccaaggcc ugcuguguac     1140

caacugaacu gagcgcaauc aguauguugu accuggauga gaacgaaaaa gugguccuca     1200

agaauuauca ggacauggug gucgaggguu gcggcugucg cugaggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  3278
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt7)

<400>  3278
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaucc       60

ccggcaacag gaugcugaug gugguccucc ugugccaggu guugcucggg ggugccagcc      120

acgcaucccu gauuccagag accggcaaga aaaagguagc cgaaauccaa gggcaugcgg      180

gcggucggcg cagugggcag agccacgagc uguugaggga cuucgaagcc acucugcucc      240

agauguuugg ccugcggcgc aggccgcagc ccuccaaaag ugcagugauu ccagauuaca      300

ugcgggaccu guaucgccuc caaagcggcg aggaagagga ggaacagauc cauuccaccg      360

ggcuggagua ccccgaaagg ccagccagcc gggcaaauac gguccgcucc uuccaccaug      420

aggagcacuu ggaaaacauu cccgguacca gugagaauag cgccuuuagg uuccuguuua      480

accucuccag caucccagaa aaugagguga ucaguuccgc ggaacugcgg cuguuccgcg      540

aacaggugga ucagggcccg gacugggaga ggggguuuca ccggauuaac aucuaugagg      600

ucaugaagcc cccagccgag gugguacccg gccauuugau uacucgccuc cuggauacca      660

ggcuggugca ccauaauguc acucgguggg aaaccuucga cgugagccca gcagugcucc      720

gcuggacgag ggagaaacaa cccaacuacg gucuggccau cgaagucacu cacuugcacc      780

agacccggac ucaucagggg cagcacguga ggauuucccg cagucugccg caaggcagcg      840

gcaauugggc ccagcuccgg ccccugcugg uaaccuuugg gcaugauggu aggggccacg      900

cauugacccg ccggaggcgc gccaagcggu ccccaaagca ucacagccag agggcgcgga      960

aaaagaacaa aaauugucgc aggcacaguc ucuaugugga cuucuccgau gucgggugga     1020

acgacuggau cguggcaccc ccaggcuacc aagccuuuua uugccauggu gauugucccu     1080

ucccacuggc cgaccaccug aauagcacga accaugcaau ugugcagacu cucgucaaua     1140

gugugaacuc cagcaucccg aaggccugcu guguacccac cgagcugagc gccaucucca     1200

uguuguaccu ggaugaguac gacaaagugg uccucaagaa cuaucaggaa augguggucg     1260

agggcugcgg gugucgguga ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  3279
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt7)

<400>  3279
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gccuggggag gcgggcccag uggcucugcu gguggugggg ucuguugugu agcugcugug      120

gcccaccgcc ccugcgccca ccccucccag cagccgcggc cgcagccgca gggggccaac      180

uguuggguga cgggggcucc cccggcagga ccgagcagcc accgcccagu ccacagagcu      240

ccaguggguu ccuguaccgg cgccucaaga cucaggagaa aagggaaaug caaaaggaaa      300

uccugagcgu gcugggucuc ccccaccggc cacgcccccu gcauggcuug cagcagccgc      360

agcccccagc ccugaggcaa caggaggaac agcagcaaca gcagcaacuc ccccgcgggg      420

agccaccccc aggccggcug aaauccgcgc cgcuguuuau guuggaucuc uauaacgccc      480

ugagcgcaga caaugaugag gacggugccu ccgaagggga gaggcagcag aguuggcccc      540

acgaagccgc aagcuccagc cagcggcgcc aaccaccccc aggcgccgcg cauccccuga      600

acaggaagag ucuccuggcc ccgggcuccg ggagcggugg cgcaucccca uugaccagug      660

cccaggauag cgcauuccug aaugacgccg auauggucau guccuuugug aaccucguag      720

aguacgacaa agaguucagc ccccggcagc gccaccauaa ggaauuuaag uucaaucuga      780

gucagauucc cgagggggaa guggucacgg ccgcggaguu uaggaucuau aaagauugcg      840

ugaugggcuc cuucaagaac caaacuuuuc ugauuagcau cuaccaggug uugcaggaac      900

accagcaccg ggacagugau cucuuccugc uggacacccg cgucgugugg gcauccgagg      960

aggguuggcu cgaauuugau auuaccgcca cuagcaaucu guggguagug accccacaac     1020

auaacauggg cuugcagcug agcgucguga cgagggacgg ggugcacguc cauccccggg     1080

ccgcaggccu cguggggagg gacgguccau augauaaaca gccguucaug guagccuucu     1140

uuaagguguc cgagguccac gugcgcacua cccggagugc gagcuccagg cgccggcagc     1200

aaagcaggaa ucgcaguacu cagucccagg acguggcccg ggucagcucc gcaagugauu     1260

acaacagcuc cgaacugaaa accgccugua ggaagcacga gcuguaugug agcuuccaag     1320

acuugggcug gcaggauugg aucaucgcac ccaaagggua cgccgccaau uacugcgacg     1380

gcgaauguag uuuuccacuc aacgcacaua ugaaugccac caaccacgcg auuguacaga     1440

cgcuggugca ucugaugaau cccgaguaug ucccaaagcc cugcugugcc ccgacuaagc     1500

ucaacgcaau cuccgugcug uacuucgaug acaacagcaa ugucauuuug aaaaaguauc     1560

ggaacauggu ggugcgcgcc ugcgguugcc acugaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  3280
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt7)

<400>  3280
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

ugaggagccu gcgggccgca gcgccccauu ccuucgucgc ccucugggcc ccacuguuuu      120

ugcugcgcag ugcacucgcc gacuucagcc uggauaacga ggugcacucc aguuuuaucc      180

auaggcgguu gcgcagccag gaaaggcggg agaugcaacg cgaaauucug uccauccucg      240

gccugccgca caggccccgg ccacaucugc aggggaagca caauagcgca cccauguuca      300

ugcucgaccu guacaacgcc auggcgguag aggaaggugg cgggccaggc ggucaggggu      360

uuuccuaucc cuacaaagcc guguucagua cccagggccc accguuggca agccugcaag      420

auucccacuu ucucacugac gccgauaugg ucaugagcuu cgugaaucug guggagcaug      480

acaaggaguu uuuccacccc cgcuaucauc acagggaauu ucgguucgau cugaguaaaa      540

uuccagaggg cgaagccguc accgcagccg aguuccgcau cuacaaggac uauauuaggg      600

agcgguuuga uaacgaaacg uuccgcaucu ccguguacca gguauugcag gagcaccucg      660

ggagggaaag cgaccuguuu cugcucgauu cccggacucu gugggcgagu gaggaagguu      720

gguugguguu cgacaucacc gccaccagca aucauugggu cgugaacccc cgccacaauc      780

ugggccucca gcuguccgug gagacucugg augggcaaag cauuaaccca aaauuggcag      840

gccucaucgg uaggcauggg ccccagaaua agcagccguu uauggucgcc uucuuuaagg      900

caaccgaggu gcacuuccgg aguauuaggu ccacgggcag caaacagcgc agucaaaacc      960

gguccaagac ucccaaaaau caggaagccc ugaggauggc caacguagcg gagaauagca     1020

gcuccgacca gcgccaagca ugcaagaaac augaacugua ugugaguuuu cgggaccucg     1080

gcuggcagga uuggaucauu gccccagagg gguacgccgc auacuauugu gaaggugagu     1140

gcgccuuccc ccugaacagc uacaugaaug cgaccaacca cgccaucguc cagacuuugg     1200

ugcacuuuau uaacccagag accgugccca agccauguug cgcaccgacc cagcugaaug     1260

ccaucuccgu ccucuauuuc gacgauagca guaacgugau ccugaaaaag uacaggaaua     1320

ugguagugcg cgcauguggc ugccauugag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  3281
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt7)

<400>  3281
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagg       60

ccagcgcagc ccugcucugc cuguugcuga ccgcggccgc auucaguccc cagggccucg      120

cccaaccagu ggggaucaac acuuccacca cguguugcua cagguuuauu aauaaaaaga      180

ucccgaaaca gcggcuggag agcuaucgca ggacuaccuc cagucacugu ccccgggaag      240

cagucauuuu caagaccaaa uuggacaagg agaucugcgc cgauccaacu cagaaguggg      300

ugcaggacuu uaugaaacau cuggauaaga aaacccaaac gcccaagcuc ugaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  3282
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt7)

<400>  3282
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugc       60

ucacccugau cauuuugcug cccgugguca gcaaguucuc cuuugugagu cucagcgccc      120

cacagcacug guccugcccg gagggcacuc uggcagggaa cgguaauagu accuguguag      180

gccccgcccc auucuugauc uuuagccaug ggaacuccau uuucaggauc gacacggaag      240

gcacuaauua cgagcaacug guggucgacg cgggugugag cgugauuaug gacuuucacu      300

auaacgaaaa acggaucuac ugggucgauc ucgagcgcca gcugcugcag aggguguucc      360

ucaauggguc ccggcaggaa cgcguaugca acaucgagaa gaaugugagu ggcauggcca      420

uuaacuggau caaugaggaa gucauuugga gcaaccaaca ggagggcauc auuaccguga      480

ccgacaugaa agggaauaac ucccauaucc uguugagcgc acugaaguau cccgccaaug      540

uggcagucga uccaguggaa agguuuauuu ucuggaguuc cgagguagcc gguagccucu      600

accgggcgga ccuggauggc guggggguca aagcccuguu ggagacuucc gaaaagauca      660

ccgcagugag ucucgacgug cuggauaagc gccuguuuug gauccaguau aacagggagg      720

gcagcaauuc ccucauuugu agcugcgacu acgauggugg gaguguccac aucuccaaac      780

aucccacgca gcacaaccug uucgccauga gcuuguuugg cgaccggauu uucuauagua      840

cuuggaagau gaaaaccauc uggauugcca acaagcacac uggcaaagau auggugcgca      900

ucaaucugca uuccagcuuc guaccacucg gggaacugaa ggugguccac ccgcuggcac      960

aacccaaagc cgaggacgac accugggaac cagagcagaa guuguguaag cucaggaaag     1020

guaacugcag cuccaccgug uguggccagg aucugcagag ucaucugugc augugugcgg     1080

agggguacgc ccucagccgg gaccgcaagu acugcgaaga ugucaaugag ugcgcauuuu     1140

ggaaccacgg cuguacgcug gguugcaaaa auacucccgg cuccuauuac uguaccugcc     1200

cagugggguu cguguugcug cccgacggca agagguguca ccaacucgua agcugcccgc     1260

ggaacgugag ugaauguucc caugauugcg uccugacuag cgaggggccc cuguguuuuu     1320

gcccagaagg uuccguguug gagcgcgacg gcaaaaccug cagugggugu agcucccccg     1380

auaauggcgg uugcagccag cucugugucc cacugagucc cguguccugg gagugcgacu     1440

guuucccagg cuaugaucug cagcucgacg aaaagagcug cgccgcaucc gggccgcaac     1500

ccuuucuguu guucgccaac agucaggaua ucaggcacau gcauuuugac ggcaccgacu     1560

acgggacucu gcucagccag cagaugggca ugguguaugc ccuggaucac gacccaguag     1620

agaauaagau uuacuucgcg cauacggcac ugaaauggau cgaacgggcc aacauggaug     1680

guucccaacg cgagagguug auugaagagg ggguggacgu ccccgagggc cuggccgugg     1740

auuggaucgg ucggagguuu uauuggaccg accgcggcaa gagccucauu gggcggagug     1800

aucugaaugg caaaaggucc aagaucauca cuaaagaaaa cauuagccag ccacgcggga     1860

ucgcagucca ccccauggcc aagcggcugu ucuggaccga caccggcauu aauccgagga     1920

ucgaguccag cagucuccag gguuuggggc gccuggugau ugcgagcucc gaucucaucu     1980

ggccaagugg cauuacuauc gacuuucuga cggauaagcu guacuggugu gacgccaaac     2040

agagcgugau cgaaauggca aacuuggaug gcuccaagcg gaggcggcug acccaaaaug     2100

acguagggca ccccuucgcc gucgcagugu uugaggacua cgugugguuc agcgauuggg     2160

ccaugcccuc cgucaugcgc gugaacaaaa ggacugguaa ggaccgggug cgccuccagg     2220

gcaguaugcu gaaaccaagc ucccucguag ucgugcaucc ccuggccaag ccaggggcag     2280

auccgugcuu guaucagaac ggcgguugug agcacauuug caagaaaagg cuggggaccg     2340

ccugguguag uugccgggaa ggcuucauga aggcgagcga cggcaaaacc ugccuggccc     2400

ucgaugggca ucagcuguug gccgguggcg agguggaccu gaagaaucaa gucacucccc     2460

ucgauauccu guccaaaacg cgcgugagcg aagacaacau uaccgagagu cagcacaugc     2520

ucguagcaga aaucauggug uccgaucagg acgauugugc cccagucggg ugcagcaugu     2580

acgcaaggug uauuuccgag ggcgaggacg cgacuugcca gugucugaag gguuuugccg     2640

gggacggcaa auugugcagc gauaucgacg aaugugagau gggcgugccc gugugcccac     2700

ccgcaaguuc caaguguauc aauaccgaag gggguuaugu cugccggugc agcgagggcu     2760

accaagggga uggcauucac ugucuggaca ucgaugaaug ccagcugggu gagcauaguu     2820

guggggagaa cgccuccugc acuaauaccg aaggcggcua uacguguaug ugcgccggga     2880

ggcucagcga gccgggucug auuuguccag acuccacucc cccaccccac uugcgcgaag     2940

augaccauca cuacagcgug cggaacagug auagcgagug cccgcugucc caugacggcu     3000

auugucucca cgauggggua ugcauguaca ucgaagcacu ggacaaguac gccugcaauu     3060

guguggucgg cuauauuggu gagaggugcc aguaccgcga ucugaaaugg ugggagcucc     3120

ggcacgcggg ccaugggcaa cagcagaagg ugaucguggu cgccgugugu guaguggucc     3180

uggugauguu gcugcuccug aguuuguggg gcgcacacua uuacaggacc cagaaacugc     3240

ucagcaagaa ccccaaaaau ccauaugaag aguccagccg cgacgugcgg uccaggcgcc     3300

ccgccgacac cgaagauggg augaguagcu gcccacaacc cugguucguc gugaucaagg     3360

agcaucagga ccugaagaac gguggccagc caguagccgg ggaggauggc caggcagccg     3420

acgguuccau gcaaccgacu agcuggcggc aggaacccca gcuguguggc auggggaccg     3480

agcagggcug cuggauucca gugaguuccg auaaagggag cuguccccaa gucauggaaa     3540

gguccuuuca caugccaagu uacgguacgc agacccucga gggcggggug gaaaagcccc     3600

acagccuguu guccgcgaau ccgcuguggc agcaacgcgc ccucgauccc ccacaucaga     3660

uggagcugac ucagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  3283
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt7)

<400>  3283
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

ccggcaggcg gauggagaug cugugcgcag ggcgcgugcc cgcccuccug uugugccugg      120

guuuccaccu ccugcaggcg gucuugagca cuaccgugau cccauccugc auuccgggcg      180

aaaguagcga caacuguacg gcccugguac aaacugagga uaaucccagg guggcacagg      240

ucuccaucac caagugcagu agcgacauga acggguacug ucuccauggc cagugcauuu      300

aucuggugga uaugucccag aauuacuguc ggugcgaagu ggguuauacc gggguccgcu      360

gugagcacuu uuuccugacu gugcaucaac cacucagcaa agaauacgua gcccugaccg      420

ugaucuugau uauccuguuu cucaucacgg ucgugggcuc cacuuauuac uucuguaggu      480

gguaucggaa ccgcaagagu aaagagccca agaaagagua cgaaagggug accagcggcg      540

acccagagcu gccccagguc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  3284
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt7)

<400>  3284
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

agggcgaaau caccacuuuc accgcacuga cggagaaguu uaaccugccc ccagggaauu      120

acaaaaagcc gaaacucuug uauugcagca acgguggcca cuuccugagg auucuccccg      180

acgggacugu ggauggcacc cgggaccgcu ccgaucagca uauccaacug caguugagug      240

ccgaaagcgu cggugaggug uacauuaagu ccaccgaaac ugggcaguau cuggcgaugg      300

acaccgaugg ccuccuguac ggcagucaga cgccaaauga ggagugucug uuucucgaaa      360

ggcuggagga aaaccacuau aauacuuaca ucagcaaaaa gcaugccgag aagaacuggu      420

ucguaggguu gaaaaagaau gguuccugca aacggggccc ccgcacccac uaugggcaaa      480

aggcaauucu guuucuccca cugcccguga gcuccgacug aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  3285
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt7)

<400>  3285
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

gcgucggggg uggcgacgug gaggauguaa cccccaggcc agggggcugc cagaucagcg      120

gucgcggggc ccggggcugu aacggcauuc cgggggcagc cgcgugggaa gccgcacugc      180

ccaggcggcg cccaaggcgg caccccuccg ugaauccacg caguagggcc gcagguagcc      240

cccggacucg cggcaggcgg accgaggaac gcccauccgg gaguaggcuc ggcgaccggg      300

gucgcgggag ggcccugccg ggcggccggu ugggugggcg cggcaggggg cgggcgcccg      360

agagggucgg cggucgcggc cgggggaggg gcacggccgc accacgcgcc gcccccgcag      420

cccgggggag caggccaggu cccgcgggca cuauggccgc aggguccauc accacccugc      480

cggcccuccc cgaagauggc gguagcggcg cauucccacc cgggcauuuu aaggacccaa      540

aacgccugua cugcaagaac ggcggguucu uuuugcggau ucaccccgau ggcagggugg      600

acggugugcg ggagaaaucc gauccacaua ucaagcugca acuccaggcc gaggaacgcg      660

gggucgugag uauuaaaggc guaugugcca auagguaucu ggcgaugaag gaggacgguc      720

ggcugcucgc aagcaagugc gugacugaug aauguuucuu uuucgagcgc cuggagucca      780

acaauuacaa caccuauagg agccggaaau acacgaguug guaugucgcc uugaagcgca      840

cuggccagua caaacugggg uccaagaccg gcccggggca gaaagccauc cucuuucugc      900

ccaugagcgc aaaguccuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  3286
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt7)

<400>  3286
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aguggauccu gaccuggauu cuccccacuc uguuguacag gagcugcuuc cauaucauuu      120

gucugguggg caccaucucc cucgccugca acgacaugac gccagagcag auggcaacua      180

augucaacug uaguagcccg gaacggcaca cccgcuccua ugauuacaug gaagggggug      240

acauuagggu gcggcgccug uuuugcagga cccaauggua uuugcggauc gauaaacgcg      300

gcaagguaaa agggacucag gagaugaaga auaacuacaa uaucauggag auuaggaccg      360

uggccgucgg caucguggcg auuaaaggug uggaaaguga guucuaucug gccaugaaca      420

aggaggggaa gcucuacgcc aaaaaggaau guaaugagga cugcaacuuu aaagaacuga      480

uccuggagaa ucauuauaac acguacgcaa gcgcaaagug gacucacaau ggcggcgaga      540

uguucgucgc ccucaaccag aaagggauuc ccgugcgggg uaagaaaacc aagaaggaac      600

agaaaacugc gcauuuucug ccaauggcca ucaccugagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  3287
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt7)

<400>  3287
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ugcuccccag cgugguccug aaauuguucc uggccgcagu gcucuccgcc cugguaaccg      120

gcgagaguuu ggaaaggcug cggcgcgggc ucgcggccgg uacuagcaac ccagacccgc      180

ccaccguguc cacggaucag cugcugccac ucggcggggg cagggaccgg aagguccgcg      240

aucugcaaga ggcagacuug gaucugcuca gggugacucu gaguagcaaa ccccaggccc      300

uggcaacccc aaauaaggag gaacacggua aacggaagaa gaaagggaag ggcuugggca      360

aaaagcgcga ccccugccuc aggaaauaca aggauuuuug uauccauggg gaaugcaaau      420

augugaagga gcugcgggcc ccauccugua uuugccaccc ggguuaccau ggcgagcgcu      480

gucacgggcu gagccucccc gucgaaaaca ggcuguauac cuacgaccau acuaccaucu      540

uggcgguggu agccgugguc cuguccagug ugugccuccu ggugauuguc ggccuguuga      600

uguuccggua ucaccgcagg gguggguacg auguggagaa ugaagagaag guaaaacucg      660

gcaugacgaa cagccacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  3288
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt7)

<400>  3288
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ugaccaagcu gcuccccgcc cuguugcugc agcacguccu ccugcauuug cugcuccugc      120

caaucgcaau uccguacgcc gagggccaaa ggaaacggcg caacacuauc cacgaauuua      180

agaaaagcgc gaagaccacg cugauuaaaa ucgaccccgc ccucaagauu aagacuaaaa      240

aggugaauac cgcagaucag ugcgccaaca gguguacccg gaauaaaggg cugccauuca      300

cuugcaaggc auucguauuu gacaaagccc gcaagcagug uuugugguuc cccuuuaacu      360

ccaugaguag cggugugaaa aaggaguucg gccaugaauu ugaucuguau gagaauaagg      420

acuacaucag gaacugcauc auugggaaag gccgguccua uaaggguacc gucaguauca      480

cgaaaagcgg gauuaagugu cagccauggu ccagcaugau cccccacgaa cauuccuucc      540

ucccaaguag cuaccgcggc aaagaucugc aagagaauua uugcaggaac ccgcggggcg      600

aggaaggggg ucccuggugu uuuacuucca auccagaggu gcgcuacgaa gugugcgaca      660

uuccccagug uagcgagguc gagugcauga ccugcaacgg cgaaaguuau agggggcuga      720

uggaucacac ugaguccggc aagaucuguc agcgguggga ccaccagacc ccacaucgcc      780

acaaguucuu gcccgaaagg uacccggaua aagguuuuga cgauaauuac ugccggaacc      840

ccgacgggca accacgcccc ugguguuaua cccucgaucc acauacgagg ugggaguacu      900

gcgcgauuaa gacuugugcc gacaauacca ugaacgacac ugaugugccc cuggaaacca      960

ccgagugcau ccagggccag ggcgaggggu aucgggguac uguaaauacg aucuggaacg     1020

gcauuccaug ucagcgcugg gacagccaau acccgcacga acacgauaug acccccgaga     1080

acuucaaaug caaggaccug agggaaaauu auugucggaa cccagauggg uccgagaguc     1140

ccuggugcuu cacuaccgac ccaaauauca gggugggcua cugcagccag auucccaacu     1200

gugauauguc ccauggucag gacugcuauc gcggcaaugg gaaaaacuac augggcaauc     1260

ucagccaaac ccggaguggg cugacuuguu ccauguggga uaagaacaug gaagacuugc     1320

acaggcauau cuuuugggag ccggaugcaa gcaagcugaa ugagaacuac ugccgcaauc     1380

cagacgacga ugcccacggu cccugguguu auacgggcaa cccccucauu ccaugggacu     1440

acugccccau cagucggugu gaaggggaua ccacuccaac caucgucaau cuggaccauc     1500

cggugauuuc cugcgccaaa accaagcagc ugaggguggu caacggcauc cccacucgca     1560

cgaauauugg uuggauggug agcuugcggu auaggaacaa acacaucugu ggcgggagcc     1620

ucauuaagga guccugggua cugaccgcac ggcagugcuu cccaagucgc gaucugaaag     1680

acuacgaagc cuggcucggc auccacgaug ugcaugggag gggcgacgag aaguguaagc     1740

agguccugaa cgugagccaa uugguguaug gucccgaagg guccgaucug guccucauga     1800

aacuggcgcg gccagccgug cuggacgauu uuguaagcac uaucgacuug cccaauuacg     1860

gcugcaccau uccggagaag accaguugcu ccguguaugg uuggggcuac acugggcuca     1920

ucaacuacga uggccugcug cgcgucgcac accucuauau uauggggaau gagaaaugua     1980

gccagcauca caggggcaag gugacgcuga acgaauccga gaucugcgcc ggugcagaga     2040

aaauugggag uggcccaugu gaaggcgacu acgggggucc cuuggucugc gagcagcaca     2100

agaugcggau ggugcugggc gugaucguac cagggcgcgg cugugccauu cccaauaggc     2160

cggguaucuu cgugcggguc gccuauuacg cgaaauggau ccauaagauu auccucaccu     2220

auaaggugcc ccagagcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  3289
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt7)

<400>  3289
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aggcagccgc gaucggcauu gaccugggga ccacuuacag cugcgugggu gucuuccagc      120

acggcaaagu ggagaucauu gccaacgauc aagggaauag gaccacgccc uccuauguag      180

cauuuacuga caccgaacgg cucaucggcg augccgcaaa gaaccaggug gcccugaauc      240

cacagaacac cgucuucgac gcgaaacgcu ugauugguag gaaguuuggg gauccggugg      300

ugcagaguga caugaaacau uggcccuucc aagucaucaa ugauggcgac aagccaaagg      360

ugcagguaag cuacaaaggc gagacuaagg ccuuuuaucc cgaagagauc uccaguaugg      420

ugcugaccaa aaugaaggaa auugcagagg ccuaccucgg guauccaguc acgaacgccg      480

ugaucacugu gcccgcauac uucaaugaua gccagcggca ggccaccaaa gacgcgggug      540

ucauugccgg ccugaacgug uugcgcauca uuaaugagcc aacugcagcc gcaaucgccu      600

augggcugga uaggaccggc aagggugaac ggaacguacu cauuuuugac cucgggggcg      660

gcaccuucga uguguccauc cugacgaucg acgacgggau uuuugagguc aaagccacug      720

cgggugauac ccaccugggc ggggaagacu ucgauaaucg ccuggugaac cauuuugugg      780

aggaguucaa gaggaagcac aaaaaggaca ucagccaaaa uaaacgggca guccgcaggu      840

ugcggacugc cugugaacgc gccaagagga cccuguccag uagcacccag gcaucccucg      900

agauugauag ccuguucgaa ggcaucgacu uuuacacuag cauuacgcgg gcccgcuucg      960

aggaacugug cuccgauuug uuuaggagca cccucgagcc gguggagaaa gcgcugcggg     1020

acgccaagcu ggauaaggca cagauccaug accucguacu gguggguggc uccacucgca     1080

uccccaaagu ccagaaguug cugcaagauu ucuuuaacgg gagggaccuc aauaaaagua     1140

uuaacccaga cgaagccgug gcauacggcg ccgccgucca ggcagccauc cugauggggg     1200

auaagagcga gaacgugcag gaccuguugc uccuggaugu ggcgccccug ucccucgguc     1260

uggaaaccgc cggcggggua augaccgcau ugauuaaacg gaauagcacu aucccaacga     1320

agcaaaccca gauuuucacu accuauagug acaaccagcc cggcgugcug auccaggucu     1380

acgaggguga aagggccaug accaaggaua auaaccuccu gggccgcuuu gagcuguccg     1440

ggaucccgcc cgccccacgg ggcgugcccc aaauugaggu cacuuucgac aucgaugcaa     1500

augggauuuu gaacgugacg gcgaccgaca aaagcacugg caaggccaau aaaaucacca     1560

uuacuaacga uaaggguagg cucaguaaag aagagaucga acgcauggug caggaggcag     1620

aaaaguauaa ggccgaggac gagguacagc gggaaagggu guccgccaaa aaugcacugg     1680

agagcuacgc cuuuaacaug aagagugcgg ucgaagauga ggggcugaaa ggcaagauuu     1740

ccgaggccga caaaaagaaa gugcucgaua agugucagga agucaucagu uggcuggacg     1800

caaauaccuu ggccgagaag gacgaguucg aacacaaacg caaggaacug gagcaagugu     1860

gcaacccaau cauuagcggu cucuaucagg gcgccggggg ccccgggcca ggcgguuuug     1920

gggcacaggg cccgaaaggc ggguccggua gcggccccac gaucgaggaa guggauugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3290
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt7)

<400>  3290
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aggcagccgc gaucggcauu gaccugggga ccacuuacag cugcgugggu gucuuccagc      120

acggcaaagu ggagaucauu gccaacgauc aagggaauag gaccacgccc uccuauguag      180

cauuuacuga caccgaacgg cucaucggcg augccgcaaa gaaccaggug gcccugaauc      240

cacagaacac cgucuucgac gcgaaacgcu ugauugguag gaaguuuggg gauccggugg      300

ugcagaguga caugaaacau uggcccuucc aagucaucaa ugauggcgac aagccaaagg      360

ugcagguaag cuacaaaggc gagacuaagg ccuuuuaucc cgaagagauc uccaguaugg      420

ugcugaccaa aaugaaggaa auugcagagg ccuaccucgg guauccaguc acgaacgccg      480

ugaucacugu gcccgcauac uucaaugaua gccagcggca ggccaccaaa gacgcgggug      540

ucauugccgg ccugaacgug uugcgcauca uuaaugagcc aacugcagcc gcaaucgccu      600

augggcugga uaggaccggc aagggugaac ggaacguacu cauuuuugac cucgggggcg      660

gcaccuucga uguguccauc cugacgaucg acgacgggau uuuugagguc aaagccacug      720

cgggugauac ccaccugggc ggggaagacu ucgauaaucg ccuggugaac cauuuugugg      780

aggaguucaa gaggaagcac aaaaaggaca ucagccaaaa uaaacgggca guccgcaggu      840

ugcggacugc cugugaacgc gccaagagga cccuguccag uagcacccag gcaucccucg      900

agauugauag ccuguucgaa ggcaucgacu uuuacacuag cauuacgcgg gcccgcuucg      960

aggaacugug cuccgauuug uuuaggagca cccucgagcc gguggagaaa gcgcugcggg     1020

acgccaagcu ggauaaggca cagauccaug accucguacu gguggguggc uccacucgca     1080

uccccaaagu ccagaaguug cugcaagauu ucuuuaacgg gagggaccuc aauaaaagua     1140

uuaacccaga cgaagccgug gcauacggcg ccgccgucca ggcagccauc cugauggggg     1200

auaagagcga gaacgugcag gaccuguugc uccuggaugu ggcgccccug ucccucgguc     1260

uggaaaccgc cggcggggua augaccgcau ugauuaaacg gaauagcacu aucccaacga     1320

agcaaaccca gauuuucacu accuauagug acaaccagcc cggcgugcug auccaggucu     1380

acgaggguga aagggccaug accaaggaua auaaccuccu gggccgcuuu gagcuguccg     1440

ggaucccgcc cgccccacgg ggcgugcccc aaauugaggu cacuuucgac aucgaugcaa     1500

augggauuuu gaacgugacg gcgaccgaca aaagcacugg caaggccaau aaaaucacca     1560

uuacuaacga uaaggguagg cucaguaaag aagagaucga acgcauggug caggaggcag     1620

aaaaguauaa ggccgaggac gagguacagc gggaaagggu guccgccaaa aaugcacugg     1680

agagcuacgc cuuuaacaug aagagugcgg ucgaagauga ggggcugaaa ggcaagauuu     1740

ccgaggccga caaaaagaaa gugcucgaua agugucagga agucaucagu uggcuggacg     1800

caaauaccuu ggccgagaag gacgaguucg aacacaaacg caaggaacug gagcaagugu     1860

gcaacccaau cauuagcggu cucuaucagg gcgccggggg ccccgggcca ggcgguuuug     1920

gggcacaggg cccgaaaggc ggguccggua gcggccccac gaucgaggaa guggauugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3291
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt7)

<400>  3291
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

ccgcaaaggg caucgccauu gggaucgacc uggguacuac cuacagcugc gugggcgucu      120

uccagcacgg gaaaguggag auuaucgcga acgaucaagg caauaggacg acucccuccu      180

auguagccuu uaccgacacc gaacggcuca uuggugaugc agccaagaac cagguggcaa      240

ugaauccaca gaacacuguc uucgacgcca aacgccugau cgggaggaag uuuaaugauc      300

cgguggugca ggcggacaug aaauuguggc ccuuccaagu caucaacgag ggcggcaagc      360

caaaggugcu gguaaguuac aaaggggaaa auaaggccuu uuaucccgag gaaauuagcu      420

ccauggugcu caccaaacug aaggagacgg cagaggccuu cuugggucau ccagucacua      480

acgccgugau caccgugccc gcauacuuua augauaguca gcggcaggcc acuaaagacg      540

cgggcgucau ugccgggcug aacgugcucc gcaucauuaa ugaaccaacc gcagccgcaa      600

ucgccuaugg ccuggauaag ggugggcagg gcgagaggca cguacugauu uucgaccucg      660

gcggggguac cuuugaugug agcauccuga cgaucgacga uggcauuuuc gaagucaaag      720

ccacugcggg ggacacccau uugggcggug aggacuuuga uaaccggcug gugucccacu      780

ucguggagga guucaagcgc aagcauaaaa aggacaucag ccaaaauaaa agggcagucc      840

ggcgccucag gacugccugu gagcgggcca agcgcacccu guccaguagc acccaggcaa      900

accuggaaau ugauuccuug uacgagggca ucgacuuuua uacuagcauu acgagggccc      960

gguucgaaga acucugcgcg gaucuguuuc gcgggacccu ggagccggug gaaaaagccc     1020

ucagggacgc aaagauggau aaggccaaaa uccacgacau cguacuggug ggcgggagua     1080

cucggauucc caagguccag cgcuugcugc aggauuacuu caaugguagg gaccucaaca     1140

aauccaucaa cccagaugag gcaguggccu acggcgccgc aguccaagcc gcgauucuga     1200

ugggggacaa gagcgaaaaa gugcaggacc uguugcuccu ggauguggca ccccuguccc     1260

ucggccugga gaccgccggu ggcguaauga ccgccuugau caagcggaau aguacuauuc     1320

caacgaagca gacccaaauc uuuacuaccu auagcgacaa ccagcccggg gugcugaucc     1380

aggucuacga aggcgagagg gccaugacca aagauaauaa ccuccugggg cgcuucgacc     1440

ugacuggcau uccgcccgca ccacggggug ugccccagau cgaggucacg uuugauauug     1500

acgcgaaugg gaucuugaac gugaccgcca cugauaaguc caccggcaaa gugaauaaga     1560

uuacuaucac caacgacaaa gguaggcuca gcaaggaaga gauugaacgc augguacugg     1620

augcagagaa guauaaagcc gaagacgagg ugcaacggga gaagaucgcc gccaaaaaug     1680

cacuggaaag uuacgcguuc aacaugaagu ccgucgugag cgaugagggc cucaaaggga     1740

agaucaguga auccgacaaa aauaagauuc uggauaagug uaacgaguug cugagcuggc     1800

ucgaggucaa ucagcuggcc gaaaaagacg aguuugacca caagaggaaa gaacuggagc     1860

agaugugcaa cccaaucauu acgaaguugu aucagggcgg guguaccggc cccgcaugcg     1920

guacugggua cgugccaggc cgcccggcca ccggccccac uaucgaagag guggauugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3292
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt7)

<400>  3292
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

ccaggggccc cgcaaucggg auugaccugg guaccacuua cuccugcgug ggcgucuucc      120

agcacgggaa gguggagauc auugccaacg aucagggcaa ucggaccacg ccaaguuaug      180

uagcguuuac ugacaccgaa cgccucaucg gugaugccgc caaaaaccag guggcaauga      240

auccgaccaa cacuauuuuc gacgcaaaga ggcugaucgg gcggaaauuu gaggaugcca      300

ccguccagag cgacaugaag cauuggcccu uccgcguggu guccgaaggc ggcaaaccaa      360

agguccaggu ggaguacaag ggggaaacga aaaccuuuuu ccccgaggag aucaguagca      420

ugguauugac uaagaugaaa gaaauugcgg aggccuaucu ggguggcaag gugcacuccg      480

cagucaucac ugugccagcc uacuuuaaug auagccaaag gcaggccacc aaagacgcag      540

ggaccauuac gggccucaac gugcugcgga ucauuaauga acccacugcc gcggccaucg      600

cauaugguuu ggauaagaaa gggugugccg gcggcgagaa gaacguccug auuuucgacc      660

ucgggggugg caccuuugau guguccaucc ugacuaucga ggacgggauu uucgaaguaa      720

agaguaccgc aggcgauacc caucugggug gcgaggacuu ugacaaucgc auggugagcc      780

accucgccga agaguucaaa aggaagcaua aaaaggauau cgggccaaac aaacgggccg      840

uccgcaggcu gcggacugcg ugcgaacgcg caaagaggac guuguccagc aguacccagg      900

ccuccauuga gaucgacagc cuguacgagg gcguggauuu cuauacuucc auuacccggg      960

cccgcuuuga ggaacucaau gcagaccugu ucagggggac ccuggaaccg guggagaagg     1020

ccuugcggga ugcgaaacuc gacaaggguc agauccaaga aaucguccug gugggcggga     1080

guacucgcau ucccaaaauc cagaagcugc uccaggacuu uuucaacggc aaagagcuga     1140

auaagagcau uaacccagau gaggccguag cauacggugc cgcagugcag gccgccaucu     1200

ugauuggcga uaaguccgaa aauguccaag accugcuccu gcuggaugug acgcccuuga     1260

gccucgggau cgagaccgca ggcgggguca ugacuccacu gaucaaaagg aacaccacca     1320

uucccacuaa gcagacgcag accuuuacua ccuacaguga caaccaaucc agcgugcugg     1380

ugcagguaua ugaaggcgag cgggccauga cuaaagacaa uaaccuccug gguaaguucg     1440

auuugaccgg gaucccgccc gcgccaaggg gcgugcccca gauugaaguc acguuugaca     1500

ucgaugccaa ugguauucug aacgugaccg cagccgacaa aaguacuggc aaggagaaua     1560

agaucaccau uacuaacgau aaagggcgcc ucuccaagga cgauaucgac cggauggucc     1620

aggaggccga aagguacaaa agcgaggaug aagcaaaucg cgaccgggug gcggccaaga     1680

acgcacugga gagcuauacc uacaauauca aacaaacggu ggaggaugaa aagcugaggg     1740

gcaaaauuuc cgagcaggac aagaacaaga ucuuggauaa augucaggaa guaauuaauu     1800

ggcucgaccg caaccagaug gccgagaagg acgaauauga gcacaaacaa aaggagcugg     1860

aacgggugug caauccaauc auuaguaaac uguaccaagg gggccccggu gggggcagcg     1920

gcgggggugg cuccggggcc agcggcgguc caaccaucga ggaagucgau ugaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  3293
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt7)

<400>  3293
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggucggcau cgaccugggg uuccaguccu gcuacguggc cguagcaagg gccgguggca      120

uugagaccau cgcgaacgaa uauagugauc gguguacucc cgccugcauu agcuuugggc      180

caaagaaucg cuccaucggc gcagccgcaa aaagucaagu gauuagcaac gccaagaaua      240

ccguccaggg uuucaaaagg uuucacgggc gggcguucuc cgacccguuu guggaggccg      300

aaaagagcaa ccucgcauac gauaucgugc agcugcccac gggcuugacu ggcaucaaag      360

ucaccuauau ggaggaagaa cgcaauuuca ccacugaaca ggugaccgcc augcugcucu      420

ccaagcugaa ggaaacggcc gagaguguau ugaaaaagcc aguggucgac ugugugguga      480

gcguccccug cuuuuacacu gaugcagaaa ggcgguccgu gauggacgcc acccaaauug      540

cggggcugaa cugucuccgc cugaugaaug agacuaccgc cguagcacug gccuauggua      600

ucuacaaaca ggaucuccca gcacuggagg aaaagcccag gaacgugguc uucguggaca      660

ugggccauag cgccuaucag gugagugucu gcgccuuuaa ucgggggaaa uugaaggugc      720

uggcgaccgc auucgauacg acucucggcg gucgcaaauu ugacgaggua cuggugaacc      780

acuucuguga agaguucggg aagaaguaca aacuggauau uaaguccaaa aucagggccu      840

ugcuccggcu gagccaggaa ugcgagaagc ugaaaaagcu cauguccgcc aaugcaagug      900

accugccauu gagcauugag uguuuuauga acgaugucga cguguccggc accaugaauc      960

gcggcaaguu ccuggaaaug ugcaacgacc uccuggccag ggucgagccg ccccugcgga     1020

gcguguugga acaaacuaaa cucaagaaag aggauaucua cgcgguggaa auuguagggg     1080

gugccacccg caucccagca gugaaggaga aaaucaguaa guuuuucggc aaggagcugu     1140

ccaccacucu gaaugccgac gaagcaguca cgagggggug cgcccuccag ugugccauuc     1200

ugagccccgc auuuaaagug cgggaguuca guaucaccga ugucgugcca uaucccauuu     1260

ccuugcgcug gaacagcccg gccgaagagg gcagcuccga cugcgaagug uuuaguaaga     1320

accaugcggc ccccuucagc aaaguacuga cuuuuuacag gaaggagcca uucacccucg     1380

aggcauauua cuccagcccc caggaucugc cauaucccga cccagccauc gcccaguuua     1440

gugugcaaaa agucaccccg caguccgaug guagcuccag uaaggugaag gucaaagugc     1500

gggugaaugu acacggcauu uucagcgucu ccagcgcaag ucugguggaa gugcauaagu     1560

ccgaggaaaa cgaggagccc auggaaacug accagaaugc gaaagaggaa gagaagaugc     1620

aagucgauca ggaggagcca cacguggagg aacagcagca acagacgccc gccgagaaca     1680

aagcagaaag cgaggaaaug gagaccuccc aggccgggag uaaggacaaa aagauggauc     1740

agccacccca agccaagaaa gcaaagguga aaacuagcac cguagacuug ccgaucgaga     1800

aucagcuccu guggcagauc gacagggaaa ugcugaaccu cuacauugag aaugaaggca     1860

agaugaucau gcaggauaaa cuggagaagg aacgcaacga cgccaagaau gcggucgagg     1920

aguaugugua cgaaaugcgg gauaaauugu ccggggagua cgaaaaguuu gugagcgagg     1980

acgauaggaa caguuucacc cugaaacucg aggacacuga aaauuggcug uaugaggaug     2040

gugaagacca accaaagcag gucuacgugg auaaacuggc cgaguugaag aaccugggcc     2100

agcccauuaa gauccgcuuc caggaauccg aggagcggcc caaacucuuu gaggagcugg     2160

ggaagcaaau ucagcaguau augaaaauca ucagcuccuu caagaauaaa gaagaccaau     2220

acgaucaccu cgacgcagcc gauaugacga agguagagaa aagcaccaac gaagccaugg     2280

aguggaugaa uaacaagcug aacuugcaga auaagcagag ucugacuaug gacccagugg     2340

ucaaaagcaa ggagauugaa gcaaaaauca aggagcucac cuccacuugu agucccauua     2400

ucagcaaacc aaagccgaag guggaacccc caaaagagga gcagaagaac gccgaacaaa     2460

auggccccgu ggacggucag ggcgauaacc cagggcccca ggcggccgag cagggcaccg     2520

acacggcagu cccguccgau agcgacaaaa agcugccaga aauggauauu gacugaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  3294
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt7)

<400>  3294
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggucggcau cgaccugggg uuccucaacu gcuacauugc cguggcaagg uccgguggca      120

ucgagaccau ugccaaugaa uauagugauc gguguacucc cgcgugcauc agccuggggu      180

cccgcaccag ggccauuggc aacgcagcca agagucagau cguaacgaau gugcggaaca      240

cuauccacgg uuuuaaaaag uugcaugggc gcagcuucga cgauccaauu guccaaaccg      300

agaggauccg gcugccguac gaacuccaga aaaugcccaa uggcuccgca ggcgugaagg      360

ugcgcuaucu ggaggaagag aggccauuug ccauugagca ggucaccggg auguugcugg      420

cgaaacucaa ggaaacuagc gagaacgccc ugaagaaacc cguggcagac uguguaaucu      480

ccauuccaag uuucuuuacc gaugccgaac ggcgcagcgu gauggccgca gcccaggucg      540

cgggucugaa uugccucagg cugaugaacg agacgacugc cguggcauug gccuacggca      600

ucuauaagca agaccugccc ccacucgaug agaaaccgcg gaaugugguc uucauugaca      660

uggggcacuc cgcauaccag gugcugguau gugccuuuaa caagggcaaa cugaaggugu      720

uggccaccac uuucgauccc uaucucggug ggcgcaauuu ugacgaagcg cuggucgauu      780

acuucugcga cgaguuuaaa accaaguaca agaucaacgu gaaagaaaau agcagggcac      840

ugcuccggcu guaucaggag ugugaaaagu ugaaaaagcu gaugagugcc aacgccuccg      900

aucucccacu gaauaucgag ugcuucauga acgaccugga cgugagcucc aaaaugaacc      960

gcgcacaguu cgagcaauug ugugccaguc uccuggcgag ggucgaaccc ccacugaagg     1020

ccgugaugga gcaggcaaau cuccagcggg aagauauuag cuccaucgag auuguaggcg     1080

gcgccacccg cauccccgca gugaaggaac agauuacgaa auuuuuccug aaggacauca     1140

gcacuaccuu gaacgccgau gaggccgucg caagggggug cgcccugcaa ugcgcgaucc     1200

ucaguccggc cuuuaaagug cgggaguucu ccauuacuga ccuggucccc uacagcauca     1260

cccugaggug gaagaccagu uuugaagaug guuccggcga gugugaagug uucugcaaaa     1320

aucauccagc acccuuuagc aaggugauua cuuuccacaa gaaagagcca uuugaauugg     1380

aggccuucua uacgaaccuc caugagguac ccuacccaga cgcccgcauc gggagcuuua     1440

ccauucagaa uguguucccg caguccgaug gcgacaguag caaggucaaa gugaaggucc     1500

gggugaacau ccacgguauc uuuuccgugg caagcgcgag uguaauugaa aaacaaaauc     1560

uggagggcga ucacuccgac gcccccaugg aaacugagac cagcuucaag aacgagaaua     1620

aggauaacau ggacaaaaug caaguggacc aggaagaggg gcaucagaag ugucacgcag     1680

aacauacccc agaggaagag aucgaucaca cuggcgccaa aacgaagucc gccgucagug     1740

acaaacagga uaggcugaau cagacccuca agaaagggaa ggugaagucc auugaccugc     1800

ccauccaguc cagcuugugc cgccagcugg gucaagaucu ccugaacagu uauauugaga     1860

augaaggcaa aaugaucaug caggacaagc uggagaaaga acggaacgau gcaaagaaug     1920

ccgucgagga auacguguau gacuucaggg aucgcuuggg gacuguguac gagaaauuua     1980

uuaccccaga ggaccugucc aagcucagcg cgguacugga agauaccgag aacuggcucu     2040

acgaagacgg cgaggaucag cccaagcagg ucuaugugga caaacugcaa gaauugaaga     2100

aauacgguca gccgauccag augaaguaua uggagcacga ggaacggcca aaagcccuga     2160

acgaccucgg caagaagauc cagcugguga ugaaagucau ugaggcauac aggaauaagg     2220

augaacggua ugaccaucug gaucccacug agauggagaa aguggaaaag uguaucuccg     2280

acgccaugag uugguugaac agcaaaauga augcccaaaa caagcugucc cucacgcagg     2340

aucccguggu aaaagucagc gagauugugg caaagaguaa ggaacuggac aauuucugca     2400

acccaaucau uuacaaaccc aagccaaaag ccgaggugcc ggaagauaag cccaaagcga     2460

auagcgagca caacgggcca auggacggcc agagcgggac cgagacuaag uccgauagca     2520

ccaaggacag uagccaacau acuaaaucca guggcgaaau ggaggucgau ugaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  3295
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt7)

<400>  3295
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ugagccucgu ggccgcaaug cuguugcugc ucuccgccgc gagggccgag gaagaggaca      120

aaaaggaaga ugucggcacc gugguaggga ucgaccuggg uacuaccuac aguugcgugg      180

gcgucuucaa aaacgggcgg guggagauua ucgcaaauga ucagggcaac cgcauuacgc      240

ccagcuaugu ggccuuuacu ccagaaggug agagguugau cggggacgca gccaagaauc      300

aacugaccuc caacccggag aauaccgucu ucgaugcgaa acggcucauu ggccgcacuu      360

ggaacgaccc cagugugcag caggauauca aguuucugcc auucaaggua guggagaaaa      420

agaccaaacc cuacauccag gucgacauug gcggggguca aacgaagacu uuugccccag      480

aagaaaucag cgcaauggug cugaccaaaa ugaaggagac ugccgaggcc uaucucggca      540

aaaaggugac ccacgcaguc gugaccguac ccgccuacuu caaugaugcg cagaggcagg      600

ccacgaagga cgcagggacu auugccggcc ugaacgugau gcggaucauu aaugaaccaa      660

ccgcagccgc caucgcguau gguuuggaua aacgcgaggg ggaaaagaac auucuggucu      720

uugaccucgg cggcgggacu uucgaugugu cccugcugac caucgacaau gguguguuug      780

aggucguggc aaccaacggc gacacucauc ucgggggcga agauuucgac cagaggguaa      840

uggagcacuu uaucaaauug uacaagaaaa agacggguaa ggaugugcgg aaagacaauc      900

gcgccgucca aaagcugagg cgggaggugg aaaaagccaa gcgcgcacug agcucccagc      960

aucaggccag gauugagauc gaaaguuucu augagggcga agauuucagc gagacccuca     1020

cucgggcgaa auuugaggaa cugaacaugg acuuguuccg cuccaccaug aagccggucc     1080

agaaggugcu ggaggauagc gaccucaaaa agagugauau ugacgaaauc gugcugguag     1140

ggggcuccac caggauuccc aaaauccaac agcuggugaa ggaguuuuuc aaugggaaag     1200

aaccaagccg ggguaucaac cccgaugagg ccgucgcaua cggcgccgca gugcaggccg     1260

gggucuuguc cggcgaccaa gacacuggug aucucgugcu gcuggacgug uguccacuca     1320

cgcugggcau ugagaccgua gggggcguga ugacuaaguu gaucccccgc aacaccgucg     1380

ugccgaccaa gaaaagucag auuuuuagca cugccuccga uaaucagccc acggucacca     1440

ucaaggugua cgaaggggag aggccacuga cuaaagacaa ccaccuccug ggcaccuucg     1500

aucugacugg uauuccccca gcaccccggg gcgugccaca gaucgaagua accuuugaga     1560

ucgacgucaa ugggauuuug agggugacgg ccgaggauaa ggguaccggc aacaaaaaua     1620

agaucacuau uaccaacgac caaaaucgcc ucacuccgga agagaucgaa cggaugguga     1680

acgaugcgga gaaauucgcc gaagaggaca agaagcugaa agagaggauu gauacccgca     1740

augaacugga gagcuaugca uacagucuca agaaccagau cggggacaaa gaaaagcugg     1800

gcgggaaauu guccagcgag gauaaggaaa cgauggagaa ggccgucgag gagaaaauug     1860

aauggcugga aagucaucag gacgccgaca ucgaggauuu uaaggcgaaa aagaaagaac     1920

ucgaggagau cgugcagccc auuaucucca agcuguaugg cagcgcaggu ccacccccaa     1980

ccggggaaga ggacacugcc gaaaaggaug agcugugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  3296
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt7)

<400>  3296
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

cccccaggga gcuggcagug ggcaucgacc ucgggaccac uuacagcugc gucggugugu      120

uccaacaggg ccggguagaa auucuggcca acgaucaggg gaaucgcacc acgccauccu      180

auguggcguu uacugacacc gagagguugg ucggcgaugc cgcaaagagu caggccgcac      240

ugaacccgca caauaccgug uucgacgcca aacggcucau cggucgcaag uuugcggaua      300

cuaccgugca aagcgacaug aaacauuggc ccuucagggu cguguccgaa gggggcaagc      360

caaaaguacg gguguguuac cgcggcgagg auaagacguu uuaucccgaa gagauuagua      420

gcaugguccu guccaagaug aaagagacug ccgaagcaua cuuggggcag ccagugaagc      480

acgccgugau caccgucccc gccuauuuca acgacagcca gaggcaggca acuaaagaug      540

ccggugcgau ugccggccug aaugugcucc ggaucaucaa cgagccaacc gcagccgcaa      600

uugccuacgg gcuggaccgc aggggcgccg gugaacggaa uguacugauc uuugaucucg      660

ggggcggcac cuucgacgug uccguccuga guauugaugc ggggguguuu gaggugaagg      720

caacggccgg ugacacucau uugggcgggg aggacuucga uaaccgccug gucaaucacu      780

uuauggaaga guucaggcgg aaacauggca aggaccucag cgguaacaaa cgcgcccuga      840

ggcggcugcg caccgcaugc gaaagggcca agcggacuuu guccagcagu acccaagcga      900

cccucgagau cgauucccug uucgaaggcg uggacuuuua uacuagcauu acgagggccc      960

gcuucgagga gcuguguucc gaucucuuuc ggaguacccu ggaaccggua gagaaggcau     1020

ugagggacgc caaacuggau aaggcacaga uccacgacgu gguccucguc gggggcagca     1080

cucgcauucc caaagugcag aagcugcugc aggauuucuu uaaugggaaa gaauugaaca     1140

aguccaucaa uccagacgag gccguggccu acggugcagc cgugcaagcg gccguacuca     1200

ugggcgauaa gugcgaaaaa gugcaggacc ugcugcuccu ggacgucgca cccuugagcc     1260

uggggcucga gaccgccggc ggugugauga ccacucugau ccagcggaac gccacgauuc     1320

caaccaagca aacucagacc uucaccacuu acagugauaa ucagcccggc gucuuuaucc     1380

agguguauga gggggaaagg gcaaugacga aagacaacaa ccuguugggc cgcuucgagc     1440

ucuccgggau uccgcccgcg ccacggggcg ugccccaaau cgaaguaacc uuugauauug     1500

acgccaaugg uauccugagc gugacugcaa ccgauaggag uacugggaag gccaacaaaa     1560

ucaccauuac gaaugacaag ggccggcugu ccaaggagga agucgagcgc auggugcacg     1620

aggccgaaca guacaaagca gaggaugaag cccagaggga ccgggucgcg gccaagaaca     1680

gccucgaggc acauguguuc cacgugaaag guagccugca ggaggaaucc uugcgcgaua     1740

agaucccaga ggaagacagg cggaaaaugc aagauaagug ucgcgaggua cuggccuggc     1800

ucgaacauaa ucagcuggcc gagaaggagg aauaugagca ccagaaaagg gaacuggagc     1860

agauuugccg gcccaucuuu aguagguugu acggcgggcc aggcgucccc gggggcagcu     1920

ccugugguac ccaagcacgc cagggggacc cgagcacugg cccaauuauc gaagaggugg     1980

auugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  3297
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt7)

<400>  3297
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

cccccaggga gcuggcagug ggcaucgacc ucgggaccac uuacagcugc gucggugugu      120

uccaacaggg ccggguagaa auucuggcca acgaucaggg gaaucgcacc acgccauccu      180

auguggcguu uacugacacc gagagguugg ucggcgaugc cgcaaagagu caggccgcac      240

ugaacccgca caauaccgug uucgacgcca aacggcucau cggucgcaag uuugcggaua      300

cuaccgugca aagcgacaug aaacauuggc ccuuccaggu cguguccgaa gggggcaagc      360

caaaaguaag gguguguuac cggggcgagg auaagacguu uuaucccgaa gagauuagua      420

gcaugguccu guccaagaug aaagagacug ccgaagcaua cuuggggcag ccagugaagc      480

acgccgugau caccgucccc acuuauuuca gcaacuccca gcgccaagcc accaaagacg      540

caggggccau ugcgggccug aaggugcucc caaucaucaa ugaggccacc gcagccgcaa      600

uugccuacgg gcuggauagg cggggcgccg guaaacgcaa cguacugauc uuugaccucg      660

ggggcggcac guucgaugug aguguccuga gcauugacgc ggggguguuu gaagugaagg      720

caacugccgg ugauacccau uugggcgggg aggacuucga caauaggcug gucaaccacu      780

uuauggagga guuccggcgc aaacauggca aggaucucuc cgguaauaag agggcccugc      840

ggcgccugag gacugcaugc gagcgggcca aacgcacccc gagcaguucc acccaggcga      900

cuuuggaaau cgacagccuc uucgagggcg uggauuuuua uaaguccauu acgagggccc      960

gguucgaaga acuguguagu gaccuguuua ggagcacccu cgagcccgua gaaaaagcac     1020

ugcgcgaugc caaguuggac aaagcacaga uccacgauuu cgugcugggu ggcgggcucc     1080

acucccaucc acagggugcc gaggucgccg caggccugcu gcaacggcag ggggccgaac     1140

aggagcacca acccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  3298
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt7)

<400>  3298
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagca       60

agggccccgc cguggggauc gaccugggua ccacuuacuc cugcgucggc guguuccagc      120

acgggaaagu agagauuauc gcaaacgauc aaggcaauag gaccacgcca aguuaugugg      180

ccuuuacuga caccgaacgg cucauuggug augcggccaa gaaccagguc gcaaugaauc      240

cgaccaacac uguguucgac gccaaacgcc ugaucgggag gcgguuugau gacgcagugg      300

uccagagcga uaugaagcau uggcccuuca uggugguaaa ugacgccggc cgcccaaaag      360

ugcaggucga guacaagggc gaaaccaagu ccuuuuaucc cgaggaagug aguagcaugg      420

uguugacgaa aaugaaggag auugcggagg ccuaccuggg gaaaacuguc accaacgcag      480

ugguaacugu gccagccuau uucaaugauu cccaaaggca ggccaccaag gacgcaggua      540

ccaucgccgg ccucaacguc cugcggauca uuaaugaacc cacggcggcc gcaaucgccu      600

acggguugga uaaaaaggug ggcgcagagc gcaacgugcu gauuuuugac cucggugggg      660

gcacuuucga ugucagcauc cugaccauug aagacggcau cuuugaggug aaauccacug      720

ccggggacac ccaccugggu ggcgaggauu ucgacaauag gaugguaaac cauuuuauug      780

ccgaauuuaa gcggaagcac aaaaaggaua ucagugagaa uaaacgcgcg gugaggcggc      840

uccgcaccgc augugaaagg gccaagcgga cucugagcuc cagcacgcag gccaguaucg      900

agauugacuc cuuguaugaa gggaucgauu ucuacaccag cauuacucgc gcaagguuug      960

aggagcugaa cgccgaccuc uuccggggca cccuggaucc agucgaaaaa gcgcugcgcg     1020

acgccaaguu ggauaagucc cagauccaug acauugugcu cgucgguggc aguaccagga     1080

ucccgaaaau ccaaaagcug cugcaggauu ucuucaaugg gaaagagcuc aacaagagca     1140

uuaaccccga cgaagcagug gccuacggcg cagccgugca ggccgcaauc cuguccgggg     1200

acaaaagcga gaauguacag gauuugcugc uccuggacgu gacuccacug aguuugggua     1260

uugaaacggc cggcgggguc augaccgugc ucaucaagcg gaacacuacc auucccacca     1320

agcaaacuca gacguuuacc acuuauuccg auaaucagcc aggcguccug auccaagugu     1380

acgaggguga gagggcgaug accaaagaca acaaucugcu cggcaaguuc gaacugacug     1440

ggauuccccc ggcaccccgc ggcgugccac agaucgaggu aaccuuugau aucgacgcca     1500

acgggauuuu gaaugugagc gccgucgaua aaaguacggg caaggaaaac aaaaucacca     1560

uuacuaauga caagggucgg cuguccaagg aggauaucga aaggauggug caggaggccg     1620

agaaauauaa ggcagaagac gagaaacagc gcgauaaggu cagcagcaaa aacucccucg     1680

aaaguuacgc guucaauaug aaggccaccg uggaggacga gaaacugcaa gggaagauua     1740

acgaugaaga caagcagaaa auccuggaca agugcaauga gaucauuaac ugguuggaua     1800

aaaaucagac ugcagaaaag gaggaauuug agcaccagca aaaagagcuc gaaaaggugu     1860

guaaccccau cauuaccaag cuguaucaga gcgccggcgg uaugccaggc gggaugcccg     1920

gcggguuccc aggcgguggg gccccgcccu ccggcggcgc aagcaguggg ccaacgaucg     1980

aggaaguaga cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  3299
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt7)

<400>  3299
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauca       60

gcgccuccag ggcagccgcg gcccggcugg ugggcgcagc cgcaagucgc gggcccaccg      120

ccgcgaggca ccaggacagc uggaacgguc ucucccauga ggccuuccgg cuggucaguc      180

gcagggauua cgcaagcgaa gccauuaagg gcgccguggu agggaucgac uugggcacua      240

ccaauuccug cguggcaguc auggagggua aacaagccaa ggugcuggaa aacgcggagg      300

gggcccggac gacuccaagc guggucgcau uuaccgccga uggcgaacgc cucgugggca      360

ugccggcaaa aaggcaggcc guaaccaauc ccaacaauac uuucuaugcc accaagcggc      420

ugauugggcg cagguacgac gauccagagg ugcagaaaga caucaagaac guccccuuua      480

agauugugcg ggcguccaau ggugaugcau ggguggaggc ccacggcaaa uuguauaguc      540

caagccagau cggggccuuc guccugauga agaugaaaga aacggcagag aacuaccucg      600

gccauacugc caagaaugcg gugaucaccg uacccgccua uuuuaacgac ucccaacgcc      660

aggcaacuaa agaugccggu cagauuagcg ggcugaaugu gcugaggguc aucaacgaac      720

caaccgcagc cgcccucgca uacggccugg acaagaguga ggauaaagug auugccgugu      780

augacuuggg cggggguacc uucgauaucu ccauucugga gauccagaag ggcgucuuug      840

aaguaaagag cacgaauggg gacacuuucc ucggcgguga ggacuuugau caagcgcugc      900

ugcggcacau ugugaaagag uucaagcgcg aaaccggcgu ggacuugacu aaagauaaca      960

uggcccucca gaggguccgg gaagcagccg agaaggccaa augugagcug uccaguagcg     1020

ugcagaccga caucaaucug ccguaccuca ccauggauuc cagcgggccc aagcaucuga     1080

acaugaaguu gacucgcgca caguuugaag gcaucgucac ggaccugauu aggcggacca     1140

ucgcgccaug ccaaaaagcc augcaggaug cagaggugag uaaguccgac auuggggaag     1200

ugauccucgu agguggcaug acuaggaugc ccaaagugca gcaaaccguc caggaucugu     1260

ucgggcgcgc cccaagcaag gccgugaacc ccgacgaggc agucgccauu ggcgcggcca     1320

uccagggugg cgugcuggca ggggauguga ccgacguauu gcuccuggac gugacuccgc     1380

ugagucucgg caucgaaacg cugggcgggg ucuucaccaa auugauuaau cggaacacua     1440

ccauccccac caagaagucc cagguguuua gcacugccgc cgauggucaa acgcaggucg     1500

agauuaaagu gugucagggg gagagggaaa uggcaggcga caauaagcug cucggucagu     1560

ucacccugau cggcauucca cccgccccac gcggggugcc ccaaaucgag guaacuuuug     1620

auaucgacgc gaacggcauu guccacguga gcgccaaaga uaaggggacc ggccgggaac     1680

agcagaucgu gauucagucc aguggugggc ugagcaaaga cgauaucgag aauaugguca     1740

agaacgcaga aaaguacgcc gaggaggaca ggcgcaaaaa ggaacgggug gaggcaguga     1800

auauggccga aggcauuauc cacgauacug agaccaaaau ggaggaguuc aaggaccaau     1860

ugccagcgga ugaaugcaac aaacucaagg aagagauuuc caaaaugagg gaacugcugg     1920

cccggaagga cagcgagacg ggcgagaaua uccgccaggc agccaguucc cuccagcagg     1980

ccagccugaa guuguuugaa auggcauaua aaaagauggc cuccgagagg gaagggagug     2040

guagcuccgg caccggggag caaaaagaag aucagaagga ggagaaacag ugaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  3300
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt7)

<400>  3300
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaggaggc aggcgggagc gaugguccca gggaaaccgc cccaacuucc gcguacagua      120

gcccggcccg gucccugggc gacaccggga ucacgccccu caguccaagc cacauuguga      180

acgauacuga cuccaauguc agcgagcagc aauccuuccu ggugguagug gcagucgauu      240

uuggcaccac caguagcggu uaugccuacu ccuucacuaa agaacccgag ugcauccaug      300

ugaugaggcg cugggaaggg ggcgacccag gcgugagcaa ccagaagacc cccacgacua      360

uuuugcugac cccagagcgg aaauuucaca guuucgggua ugcagcccgc gauuuuuacc      420

augaccucga uccgaaugag gcgaagcagu ggcuguauuu ggaaaaauuc aagaugaagc      480

ugcacacuac cggugaccuc accauggaua cggaccugac ugccgcaaac ggcaaaaagg      540

ucaaagcccu ggagaucuuu gccuacgcac uccaguauuu caaggaacaa gcccugaaag      600

aguuguccga ucaggcgggg agcgaguuug aaaauuccga cgugaggugg guaauuaccg      660

ugcccgccau cuggaagcag ccagcaaaac aguucaugcg gcaagccgca uaccaggccg      720

gccuggccag ucccgagaac agcgaacagc ucaucauugc gcuggagcca gaagcagccu      780

ccaucuacug ucgcaagcug agguugcauc agaugauuga gcucagcagu aaggccgcag      840

ucaaugguua uuccgggagc gacacugugg gcgccggcuu uacccaagcg aaagagcaca      900

uccggcgcaa caggcagagu cggaccuucc ugguggaaaa ugucauuggg gagaucuggu      960

ccgaacugga ggaaggugau aaguacgugg uaguggacag cggcgggggc acugucgauc     1020

ucacggugca ccagauucgc cugcccgagg gucauuugaa agagcuguau aaggccaccg     1080

gcgggccgua cggcagccuc gggguggacu augaguucga aaaacugcug uacaagaucu     1140

uuggugaaga uuucaucgag caauuuaaga uuaaaaggcc cgcagccugg gucgacuuga     1200

ugaucgcauu cgaaucccgg aagcgcgccg ccgcaccaga uaggacuaac ccccucaaua     1260

uuacccugcc auuuaguuuc aucgacuauu acaaaaaguu ucggggccac agcguggagc     1320

augcccugcg caaauccaac guagauuucg ugaaguggag cagucagggg augcucagga     1380

ugucccccga cgcgaugaau gcccuguuua agccaaccau ugauagcauc aucgagcacu     1440

ugcgggaccu guuccagaaa ccggaagucu ccacugugaa guuucucuuc cuggucggcg     1500

guuuugcaga ggcaccccug uugcagcaag ccgugcaggc cgcguucggc gaccagugca     1560

ggauuaucau uccacaggau guggggcuca cgauccugaa aggcgccgua cuguucgggc     1620

ucgaccccgc agugauuaag guccgccgga guccacugac cuacggcgug ggugucuuga     1680

acagguaugu ggaagggaaa caucccccgg agaagcugcu cgugaaggau ggcacucgcu     1740

gguguaccga cguauuugau aaauucauca gcgccgacca auccguggcc cugggugagc     1800

uggucaagcg gagcuacacc ccagcaaaac ccagucaguu ggugaucguc auuaauaucu     1860

auuccagcga acacgauaac guguccuuua uuacugaccc cggcgugaag aaaugcggga     1920

cgcugaggcu cgaucugacc ggcaccagug ggacugccgu accagcgcgc cgggagaucc     1980

agacucucau gcaguucggc gacaccgaaa uuaaggccac ggcaaucgau auugccacca     2040

gcaaauccgu caaggugggu aucgacuuuc ugaacuacug aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  3301
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt7)

<400>  3301
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugg       60

ccgugcccga gaugggccuc caggggcugu acaucgguag cuccccagaa aggaguccgg      120

uccccagccc acccggcucc ccacggaccc aagagaguug cgggauugca cccuugacuc      180

caagccaguc cccgaagccc gaagugcgcg ccccacagca ggcgagcuuc uccguagugg      240

ucgccaucga cuuuggcacc acgaguagcg guuaugcauu cuccuuugcc agcgaucccg      300

aggcaauuca caugaugagg aaaugggaag ggggcgaccc aggcguggcc caucaaaaga      360

cucccaccug ucugcuccug accccggagg gggcguucca caguuuuggu uacacugccc      420

gggauuauua ccaugacuug gaucccgagg aagcacgcga cuggcuguau uucgagaaau      480

uuaagaugaa aauccacucc gccaccgauc ucacgcugaa gacucagcug gaagccguga      540

acggcaagac caugccagca cucgaggucu ucgcccaugc gcugagguuu uuccgggagc      600

acgccuugca ggaacugcgc gagcagagcc ccucccuccc agaaaaagac acugugaggu      660

ggguacugac cgugcccgca auuuggaagc aaccagccaa acaguuuaug cgggaggcag      720

ccuaccuggc cggguugguc agucgcgaaa augcggagca gcuccugauc gcacuggagc      780

cggaagccgc cagcguguau ugcaggaagc uccggcugca ccaguugcug gaucucuccg      840

gccgcgcacc cggugggggc aggcugggcg agcggcgcag caucgacagu uccuucaggc      900

aagcccggga acagcugcgc aggagccggc auaguaggac cuucuuggug gaguccgggg      960

ucggugaacu cugggcggag augcaggccg gcgaucgcua cgugguagca gacugugggg     1020

gcgguacggu ggaucugacu guccaccaac uggagcagcc acauggcacc cucaaagaac     1080

uguacaaggc cagcgggggc cccuaugggg cagugggugu ggacuuggcc uuugagcagc     1140

ugcucugccg gauuuucggc gaagacuuua ucgccacuuu caaaaggcag cgcccagcag     1200

ccugggucga ucugaccauu gcguuugagg cccggaagag gaccgcaggg ccccaccgcg     1260

ccggcgcccu gaacaucagc uugccguucu ccuuuauuga cuucuaccgg aagcaaaggg     1320

gucacaaugu ggaaacugca cuccggcgca guagcguaaa cuuugugaaa ugguccagcc     1380

agggcaugcu gaggaugagu ugugaggcga ugaaugagcu guuccagcca acggucuccg     1440

ggaucauuca gcauaucgaa gcccuccugg cacggcccga ggugcaaggc gucaaguugc     1500

uguuucucgu agggggcuuc gccgaaagcg ccgugcugca gcacgcagug caggccgcgc     1560

ugggugcccg cggguugagg guggucgugc cccaugaugu cggccugacc auccucaaag     1620

gugcagugcu guuuggccag gccccagggg ugguacgggu gcgcaggagu ccccucacuu     1680

auggcgucgg ggugcugaac cgguucgucc caggcaggca cccgcccgag aaguugcugg     1740

ugcgcgacgg ucggaggugg ugcaccgaug uguucgagcg cuuuguagcc gcagaacaau     1800

ccgucgcccu cggggaggaa gugcggagga gcuacugucc agcgcgcccc ggccagcgga     1860

gggugcugau uaaucuguau ugcugugccg cagaggacgc ccgcuucauc accgauccag     1920

gcguccggaa augcggggca uugucccugg aacucgagcc cgccgacugc ggucaggaua     1980

cugcgggcgc cccgccaggg aggcgcgaga uucgggcagc caugcaguuu ggcgacacgg     2040

aaaucaaggu gaccgccgug gauguaagca cuaacaggag uguccgcgca uccauugacu     2100

uccugagcaa uugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  3302
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt7)

<400>  3302
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

gggagaugac cauccugggc agcgcagugc ucacucuguu gcuggccggg uaccucgcgc      120

agcaauaucu gcccuugcca accccgaagg ucauugguau cgaccugggc acgacuuacu      180

gcuccguggg gguauucuuu cccggcaccg guaaagugaa ggucauucca gaugaaaacg      240

ggcacaucag uauucccagc augguguccu ucaccgacaa ugauguguau gucggcuacg      300

agagugugga acucgccgac agcaacccac agaauacuau cuaugaugca aaacgguuua      360

ucggcaagau uuucaccgcc gaggaacugg aggcagagau cgggcgcuac cccuuuaaag      420

uacugaacaa gaaugguaug guggaguucu ccgucacgag caacgaaacu auuaccgugu      480

ccccagaaua ugugggcagu aggcuccugu ugaagcugaa agagauggcc gaggcguacc      540

ucgggaugcc ggucgccaau gcagugauca gcguacccgc cgaauuugac cugaagcagc      600

ggaacuccac uauugaggcc gcaaaucugg ccggcuugaa aauccuccgc gugauuaacg      660

aaccaaccgc ggccgcaaug gccuacgguc ugcauaaggc agaugucuuc cacgugcugg      720

ugaucgaccu cgggggcggc acccuggaug ucagcuugcu gaauaaacaa ggggguaugu      780

uucucacgag ggccaugagu ggcaacaaua agcucggggg ccaggacuuc aaccagcggc      840

uguugcagua ucucuacaaa cagaucuauc aaacuuacgg uuuugugccc ucccgcaagg      900

aggaaauuca uaggcugcgg caggccguag agauggugaa gcugaaucuc acccugcacc      960

agagcgcgca guuguccguc cugcucacug uggaggaaca agaucgcaaa gagccacaua     1020

guagcgacac cgaacugccc aaggauaaac uguccagcgc agacgaccac agggucaaca     1080

guggcuucgg gcggggcuug uccgauaaga aaagcgggga gagucaggug cuguucgaaa     1140

ccgagaucuc ccgcaagcug uuugacacuc ugaacgagga ucucuuccag aagauucugg     1200

ugccgaucca acagguauug aaagaagguc accuggagaa gacggaaauu gacgaggugg     1260

uccucguggg cgggagcacc aggauccccc ggauccgcca ggucauucag gaauuuuucg     1320

gcaaagaucc aaauacuagc guggaccccg aucuggccgu gguaaccggu guggccaucc     1380

aagcaggcau ugacgggggc uccuggccac ugcaggucag ugccuuggag auccccaaca     1440

agcaucugca gaaaaccaau uuuaacugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3303
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt7)

<400>  3303
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

caaucggcgu gcaccugggg ugcaccagcg ccugugucgc gguguacaag gacgguaggg      120

ccggcguagu ggcaaacgau gccggggacc gggucacucc cgcaguggug gccuauuccg      180

agaaugaaga gauugucggc cucgcggcca aacagagucg caucaggaac auuagcaaua      240

ccgugaugaa gguaaaacaa auccuggguc gguccaguag cgauccacag gcacagaagu      300

acauugccga auccaaaugc uuggugaucg agaagaacgg gaagcugcgc uaugaaaucg      360

acacgggcga ggagacuaaa uucgucaauc cggaagaugu ggccaggcuc auuuuuagca      420

agaugaaaga gaccgcacau uccgugcugg gcagugacgc caacgauguc gugaucaccg      480

uacccuucga cuuuggggaa aagcagaaaa augcguuggg ugaggccgca cgggccgcag      540

gcuucaacgu gcugcgccuc auucacgagc caagcgccgc ccugcuggcg uacgggaucg      600

gccaagauuc ccccacuggu aagagcaaua uucucgucuu uaaacugggc gggaccaguu      660

ugucccugag cgugauggaa gugaacuccg gcaucuauag gguccucagu acgaauacug      720

acgauaacau ugggggugca cauuucaccg agacucuggc ccaguaccug gccagcgaau      780

uucagcgguc cuucaagcac gacgugcgcg gcaaugcaag ggccaugaug aaguugacca      840

acagcgcgga gguagccaaa cauagucucu ccacccuggg gagcgcaaau uguuuucugg      900

auagucucua ugaaggccag gacuucgacu gcaacguguc ccgggcccgc uuugagcugu      960

uguguagccc acuguucaac aagugcaucg aggcaaucag gggucuccug gaucaaaaug     1020

gcuucacggc cgacgauauu aacaaagucg ugcugugugg gggcagcucc cggaucccca     1080

aguugcagca gcucauuaaa gaccuguuuc cagccgucga acugcucaau aguaucccgc     1140

ccgaugaggu gauuccaauc ggggcagcca ucgaagcggg uauucugauc ggcaaggaga     1200

acuugcuggu ggaagacagc cucaugauug agugcuccgc ccgcgauauc cugguaaagg     1260

ggguggacga gagcggcgca aguagguuca cuguccuguu ucccuccggu accccauugc     1320

ccgcccggcg ccagcacacu cuccaagccc cgggcagcau uuccagugug ugucuggaac     1380

uguacgagag cgaugggaaa aauuccgcaa aggaagagac caaauucgcg caggucgugc     1440

uccaggaccu ggauaagaaa gaaaacggcu ugagggacau ccuggccgug cucaccauga     1500

agcgggacgg gagccugcac guaacuugca cggaucaaga gaccggcaag ugcgaggcaa     1560

ucaguauuga aaucgccucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  3304
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt7)

<400>  3304
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uggucggccu ggacgugggg ucccagaguu gcuacaucgc cguagcaagg gccgguggca      120

uugaaaccau cgcgaacgag uucagcgauc gguguacucc cuccgugauu aguuuuggga      180

gcaagaaucg caccaucggc gucgccgcca aaaaccaaca gauuacgcac gcaaauaaca      240

cuguguccaa uuucaagagg uuucaugguc gggcauucaa cgacccauuu auccagaaag      300

agaaggaaaa ucucagcuau gaucuggugc cguugaaaaa cgggggcguc ggcaucaagg      360

ugauguacau gggggaggaa caccuguucu ccguagagca gauuaccgcc augcuccuga      420

ccaaguugaa agagacugcg gaaaauaguc ugaagaaacc cgugaccgac ugcgucauca      480

gcgugccauc cuuuuucacg gaugccgagc gcaggagcgu gcucgacgca gcccaaauug      540

ucggucugaa cugucugcgg cucaugaaug auaugacugc cguggcacug aacuauggca      600

ucuacaagca ggacuugccc agucuggaug aaaaaccacg cauuguagug uuugucgaca      660

uggggcauuc cgccuuccag gugagcgcgu gcgccuuuaa uaagggcaaa cucaaggugc      720

uggguaccgc auucgauccc uuccugggcg ggaagaacuu ugacgagaaa uuggucgagc      780

acuucugugc cgaauuuaag acuaaauaua agcucgaugc aaaauccaag aucagggccc      840

ugcugcggcu cuaccaggag ugcgaaaagc ugaaaaaguu gaugaguagc aauuccaccg      900

accugccacu caacauugag uguuucauga acgacaaaga ugugagcggc aagaugaauc      960

gcagucaauu ugaagaacug ugcgccgagc uguugcagaa aaucgaagua ccgcucuauu     1020

cccugcugga gcagacccau cucaaggugg aagacgucag cgcgguggag aucgucgggg     1080

gugcaacgag gauucccgcc gugaaggaac ggaucgccaa auucuuuggc aaggauauua     1140

guacuacccu gaacgcagac gaggccgugg cgcgcgggug ugccuugcag ugcgcaaucc     1200

uguccccagc cuucaaagua agggaguuua gcgugacuga ugcagucccc uucccaauua     1260

gccucaucug gaaucacgac uccgaagaua ccgagggcgu gcacgaaguc uuuagucgga     1320

accaugccgc ccccuucagc aaggugcuga ccuuucugcg cagggguccg uucgaguugg     1380

aagcauucua cuccgacccc caaggcgugc cauaccccga ggccaaaauc gggcgguuug     1440

uagugcagaa ugucagcgcg cagaaggaug gcgagaagag ucgcgugaaa gucaagguga     1500

gggugaacac ucacgggauu uucacgaucu ccaccgccag caugguagaa aaagucccaa     1560

cugaggaaaa ugagaugucc agugaggcag acauggaaug ccucaaccaa cggcccccag     1620

agaauccgga uaccgacaag aacgugcagc aggacaauag cgaagccggu acccagcccc     1680

aagugcagac ugaugcccag cagacguccc aaagcccacc caguccagag cugaccuccg     1740

aagagaacaa aauucccgac gcagauaagg cgaaugagaa aaaggucgac cagccgccag     1800

aagccaagaa acccaagauc aaagugguga acguagagcu gcccauugaa gcaaaucucg     1860

ucuggcagcu gggcaaggau uugcugaaca uguauaucga gacugaaggg aaaaugauca     1920

ugcaggacaa gcucgagaag gagaggaacg augccaaaaa ugccguggaa gaguacgugu     1980

augaauuucg cgacaagcug uguggcccau acgagaaauu cauuugcgaa caagaucauc     2040

agaacuuucu gcgguugcug accgagaccg aggacuggcu cuaugaagag ggugaagauc     2100

aggcaaagca ggccuacguc gacaaacugg aggagcucau gaagaucggc acucccguga     2160

agguaagguu ccaagaagcg gaggaacgcc caaaaauguu ugaggaacug gggcagcggu     2220

ugcagcacua ugccaagauu gcagccgauu ucaggaauaa agacgagaag uacaaccaca     2280

ucgacgagag cgaaaugaaa aagguggaga aauccgucaa ugaagugaug gaguggauga     2340

acaaugugau gaacgcccaa gcaaagaaga gucuggauca ggacccgguc gugcgcgccc     2400

aggaaauuaa aacgaagauc aaagagcuca auaacaccug ugagcccgua gugacucagc     2460

caaagcccaa aauugaaagc ccaaagcugg agcggacccc caauggcccg aacaucgaua     2520

agaaagaaga ggaccuggag gauaagaaua acuuuggggc ggaaccaccc caucaaaaug     2580

gcgagugcua cccaaacgag aaaaacuccg ucaauaugga cuuggauuga ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  3305
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt7)

<400>  3305
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaggugag gcggcagcgc cccaggcggc gcgucugcug ggcacuggug gccguacucc      120

uggcggauuu gcuggcccuc agcgacaccc uggcagugau guccgucgau uugggcagug      180

agagcaugaa aguggccauc gugaagccag gggucccgau ggaaauugug cugaacaaag      240

aguccaggcg gaagacuccc guaaucguga cccucaaaga aaaugagcgc uucuuuggug      300

acagugcagc cagcauggcg auuaagaacc caaaggccac gcugagguac uuccaacauc      360

ugcucggcaa acaggcagau aauccccacg ucgcccugua ucaggcccgg uuuccagaac      420

acgaguugac uuucgacccc cagcgccaaa ccgugcauuu ucagaucucc agccagcugc      480

aguucucccc agaggaagug cucgggaugg uccugaacua caguaggagc cuggcagagg      540

auuuugccga acaaccgauu aaggacgcgg ugaucaccgu acccguguuc uuuaaucagg      600

ccgagcggcg cgcagucuug caggccgcaa ggauggccgg ccucaaagug cugcagcuga      660

ucaacgauaa uacugccacc gcgcucuccu augguguguu ccggcgcaag gacauuaaca      720

cgacugcaca aaauaucaug uuuuacgaua uggggagcgg caguaccguc uguacuauug      780

ugaccuauca gaugguaaaa accaaggagg ccggcaugca gccacaacug cagaucaggg      840

gugugggguu cgaccggacg uugggcgggc uggaaaugga gcuccgccug agggaacggc      900

uggccggcuu guucaacgag cagaggaaag gucagcgcgc aaaggauguc cgggaaaauc      960

ccagggccau ggcgaagcuc cugcgcgagg ccaaccggcu gaaaacugug cucuccgcaa     1020

augccgacca cauggcacaa auugaggggc ugauggacga ugucgacuuu aaggccaaag     1080

ugaccagggu ggaguucgag gaauugugcg ccgaucuguu ugagcgcgua ccaggccccg     1140

ugcagcaggc acuccagagc gccgaaaugu cccuggacga gaucgagcaa gucauucugg     1200

ugggcggggc gacucggguc ccgagggugc aggaaguguu gcucaaggcc guagguaaag     1260

aggaacuggg caagaacauc aaugcagaug aggccgccgc aaugggggcg guguaccagg     1320

ccgcagcccu gaguaaggcc uucaaaguca agcccuuugu gguccgggac gcaguggugu     1380

auccaauccu cguagaguuc acccgcgagg ucgaggaaga acccggcauu cauagccuga     1440

aacacaacaa gaggguguug uuuucccgga uggguccaua cccccagcgc aaagugauca     1500

ccuucaacag guacagccac gauuuuaauu uccauauuaa cuauggcgac cugggguuuc     1560

ucggcccaga agaucugcgg gucuucggga gucaaaaucu gacuacggug aaguugaagg     1620

gugugggcga cuccuuuaaa aaguacccgg auuaugagag caaagggauc aaggcccacu     1680

ucaaccugga cgagaguggc guacucuccc uggaccgcgu cgaaagcgug uucgagaccc     1740

ucguggaaga uagcgcggag gaagagucca cucugaccaa auuggguaau accauuagua     1800

gccuguuugg cgggggcacu acgcccgacg ccaaggagaa cgggaccgau acuguccagg     1860

aagaggaaga guccccagca gaaggcagca aggacgagcc cggugaacag guggaacuca     1920

aagaggaagc cgaggcccca guagaagaug ggagucagcc cccgccaccc gagcccaagg     1980

gcgacgcaac cccagagggu gaaaaagcca ccgagaagga aaauggcgau aaauccgagg     2040

cgcaaaagcc cagcgagaaa gccgaagcag ggccagaggg cguggccccg gcacccgaag     2100

gggagaagaa gcagaaacca gccaggaagc ggaggauggu cgaagagauc ggcguggagc     2160

uggugguccu ggacuugccc gaucugccag aagacaaacu cgcgcagucc gugcaaaagc     2220

ugcaggaucu cacucugcgc gacuuggaga aacaggaacg ggagaaggcc gcaaacaguc     2280

uggaagccuu caucuuugag acgcaggaua agcuguacca acccgaguau caggaaguaa     2340

gcaccgagga acagagggag gagauuuccg guaaacucag cgccgcaagu acuuggcugg     2400

aagacgaggg ggugggcgcc accacuguca uguugaagga aaaacuggcg gagcuccgca     2460

agcuguguca gggccucuuc uuucgggugg aagagaggaa aaaguggccg gagcgccugu     2520

ccgccuugga caaucugcug aaccauagcu ccauguuccu caagggggca cggcugaucc     2580

cagaaaugga ucaaauuuuu accgaggugg aaaugacgac cuuggagaaa gucaucaaug     2640

aaacuugggc cuggaagaac gcaacccugg ccgagcaggc caaacucccc gcaacugaga     2700

agccagugcu gcugaguaaa gacauugaag cgaagaugau ggcccucgau agggagguac     2760

aguaccuguu gaauaaagcc aaguucacca agccccgccc gcggcccaaa gacaagaacg     2820

guacgagggc agaaccaccc cugaaugcca gcgcauccga ucagggcgag aaagugaucc     2880

cacccgccgg gcaaaccgaa gacgcggagc caaucagcga gccggaaaag gucgagacug     2940

gcagugaacc cggugauacc gagccacucg agcugggcgg gcccggcgcc gaaccagagc     3000

agaaagaaca guccacuggg caaaagcgcc ccuugaagaa cgacgagcug ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3306
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt7)

<400>  3306
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggaaaccca gacucaagac cagccaaugg aggaagagga aguggagacc uucgccuuuc      120

aggcagagau cgcccagcug augagccuca uuaucaacac guucuacucc aauaaggaaa      180

uuuuucugag ggaguugauc aguaacagcu ccgaugcgcu ggacaaaauu cgguaugaaa      240

gucucacuga uccgagcaag cuggacuccg gcaaagaguu gcacaucaau cugaucccca      300

acaagcaaga ucgcacccuc accauugucg acacugggau cgguaugacc aaagccgauc      360

ugauuaauaa ccugggcacg aucgcaaaga gcgggacuaa ggccuucaug gaggcacucc      420

aggccggcgc ggacauuucc augaucgguc aguuuggggu gggcuucuac agugccuauc      480

ugguagcaga aaaagugacc gucauuacua agcauaauga ugacgagcag uacgccuggg      540

aaagcuccgc cggcgggagc uuuaccguga ggaccgauac gggugagcca augggccggg      600

ggacuaaagu gaucuugcac cugaaggaag accaaaccga guaucucgag gaacgcagga      660

ucaaagagau ugucaagaaa cauagucagu ucaucggcua ccccauuacu cuguuugugg      720

aaaaggagcg ggauaaggaa guauccgacg acgaggcaga ggaaaaagag gauaaggaag      780

aggaaaaaga gaaggaggaa aaagagagcg aagacaagcc agagaucgag gauguggguu      840

ccgacgaaga ggaagagaag aaagaugggg acaagaaaaa gaaaaagaag auuaaagaaa      900

aguauaucga ucaggaggag cugaacaaaa ccaagcccau cuggacccgc aauccagacg      960

auauuacuaa cgaagaguac ggcgaguucu acaaaaguuu gacgaaugac ugggaggauc     1020

accucgccgu caagcauuuu agcguggaag gccagcugga guucagggcg cuccuguucg     1080

ugccgcggcg cgcccccuuu gaccuguucg agaacaggaa gaaaaagaau aacaucaaau     1140

uguauguccg gcgcguguuu auuauggaca auugcgaaga acugauccca gaauaccuca     1200

acuucauuag ggguguagug gauuccgagg accugccccu gaacaucagc cgggaaaugu     1260

ugcaacagag uaagauccuc aaagucauuc gcaagaaucu ggugaaaaag ugucuggagc     1320

ucuuuaccga gcuggcagaa gauaaggaga acuauaaaaa guucuacgaa caguuuucca     1380

aaaauaucaa guuggggauu cacgaggaca gccaaaacag gaaaaagcug agugagcucc     1440

ugcgguauua cacuuccgcc agcggcgaug aaauggugag ccugaaggac uauugcaccc     1500

gcaugaaaga gaaucagaag cacaucuacu acauuaccgg ggaaacuaaa gaucaggucg     1560

caaacuccgc cuucguggag agguugcgga agcauggccu cgaaguaauc uauaugauug     1620

agccaaucga cgaguacugu gugcagcaac ugaaagaauu ugaggguaag acgcugguca     1680

gugugaccaa ggaaggccuc gagcugcccg aagaugagga ggagaaaaag aaacaggaag     1740

aaaagaaaac uaaguucgag aauuugugca aaaucaugaa ggacauucug gagaagaaag     1800

ucgaaaaggu ggugguaagc aacaggcucg ugaccucccc guguugcauc gucaccagca     1860

cuuaugggug gacggccaau auggagcgca uuaugaaagc gcaggcacug cgggauaaca     1920

guaccauggg cuacauggcc gccaagaaac accuggaaau caaucccgac cauuccauua     1980

ucgagacuuu gaggcagaag gcagaagccg auaagaacga caaaagcgug aaggaccugg     2040

ucauccuccu guaugagacc gcgcuccugu ccaguggguu uagcuuggag gauccacaaa     2100

cucacgccaa ucgcauuuac cggaugauca aacugggucu cggcauugac gaagaugacc     2160

ccaccgcaga ugacacgucc gccgcaguga ccgaggaaau gccaccccug gagggggaug     2220

acgauacuag caggauggaa gagguggacu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  3307
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt7)

<400>  3307
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcuccaagcu ggauaguggc aaagggcucc acaucaaccu ggugcccaau aagcagaacc      120

aaaccuugac uauugucgac accaggaucg guaugacgaa aacugaucug auuaauaacc      180

ucggcaccgu gaccaagagc gggacuaaag ccuucaugga ggcacugcag gccgacgcgg      240

auaucuccau gauuggccau uuugguguag gguucuacag ugccuauuug guggcaaaga      300

aggucaccgu gaucagcaaa cacaauaacg acgaacagua cacgugggag uccagcgccg      360

gcggcuccuu uacugugcgg accgaugaau gaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  3308
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt7)

<400>  3308
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggaagugca ccauggcgag gaagaggucg aaaccuucgc cuuucaggca gagaucgccc      120

aacugaugag ccucauuauc aacacuuucu acuccaauaa ggagauuuuu cugagggaau      180

ugaucaguaa cgcgagcgac gcccuggaua aaauucggua ugagucccuc accgacccaa      240

guaagcugga uagcgggaaa gaauugaaga ucgacaucau uccgaauccc caggagcgca      300

cgcugacucu cguggauacc gguaucggca ugaccaaagc agaccugauu aacaaucugg      360

ggacuaucgc caaguccggc accaaggcau ucauggaggc ccuccaggcg ggugccgaua      420

uuagcaugau cgggcaguuu ggcguaggcu ucuacuccgc auaucuggug gccgaaaaag      480

ucguggugau uacgaagcac aacgacgaug agcaauacgc cugggaaagu agcgcagggg      540

guuccuuuac ugucagggcc gaccauggcg agccaaucgg gcggggcacc aaagugaucu      600

ugcaccugaa ggaagaucag acugaguauc ucgaggaacg caggguaaaa gaggugguca      660

agaaacauag ccaguucauu gguuacccca ucacccugua ucuggaaaag gagcgggaaa      720

aggagauuag ugacgaugag gcggaagagg aaaaagggga gaaggaagag gaggacaaag      780

acgaugaaga gaagccaaaa aucgaagacg ugggcuccga ugaggaggac gauagcggca      840

aggacaagaa aaagaaaacc aagaaaauua aggaaaagua caucgaucag gaggaauuga      900

auaaaacgaa gcccaucugg acucgcaacc cagacgauau uacccaagag gaauacgggg      960

aguuuuauaa aucccucacu aaugacuggg aggaucaccu ggccgugaag cacuucagug     1020

ucgaagguca gcuggaguuu agggcacucc uguucauccc gcggcgcgcc cccuucgacu     1080

uguuugaaaa caaaaagaag aaaaauaaca uuaagcugua cgugaggcgg guauucauca     1140

uggacagcug cgaugagcuc auuccagaau aucugaauuu uauccgcggc guggucgacu     1200

ccgaggaucu gcccuugaac aucagcaggg agaugcucca gcagaguaaa auucugaagg     1260

ugauccggaa aaauauugug aagaaauguc uggaacucuu cuccgagcug gcagaagaca     1320

aggagaacua caagaaauuu uaugaagccu ucagcaagaa cuugaaacug gggauccaug     1380

aggauaguac caaucgcagg cggcucuccg agcugcugcg cuaccacacc agccaaagcg     1440

gcgacgaaau gacuuccuug agugaguaug ucagcaggau gaaggaaacg cagaaaucca     1500

uuuacuacau caccggugag agcaaggaac agguggccaa cagugcguuu guagagcggg     1560

ugaggaagcg cggcuucgag gucguguaua ugacugaacc aauugaugag uacugcgucc     1620

aacagcucaa agaauuugac gggaaguccc uggugagcgu gaccaaagag ggccuggagc     1680

uccccgaaga ugaggaagag aagaaaaaga uggaagaguc caaggcaaaa uucgagaauc     1740

uguguaaguu gaugaaagaa auccuggaca agaaaguaga gaaggugacc aucaguaacc     1800

ggcucgucag cuccccgugc uguauuguga cuagcacgua uggguggacc gccaauaugg     1860

aaaggaucau gaaagcccag gcacugcgcg auaacaguac uauggguuac augauggcca     1920

agaagcaucu ggagauuaau cccgaccacc caaucgucga gaccuugcgg cagaaagcgg     1980

aagccgauaa gaacgacaaa gcagugaagg accugguggu acuccuguuu gagaccgccc     2040

uccuguccag cggcuucucc uuggaagauc cccaaacuca caguaauagg auuuaucgca     2100

ugaucaaacu ggggcucggc aucgacgagg augaaguggc agccgaggag ccaaacgccg     2160

caguccccga cgaaauucca ccgcuggagg gugaugaaga cgccagccgg auggaggaag     2220

uggauugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  3309
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt7)

<400>  3309
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaggg       60

cccugugggu gcucggccug ugcugugucu ugcugaccuu cgggagcgug cgggcagacg      120

augagguaga cguggauggu acugucgaag aggaccucgg caagucccgc gaagggagua      180

ggaccgauga cgagguggug cagcgggaag aggaggccau ccaacuggau ggcuugaacg      240

cgagccagau ucgcgaacug agggagaaau ccgaaaaguu ugccuuccag gcagagguca      300

aucggaugau gaaacucauc auuaacaguc uguacaagaa uaaagagauc uuucugcgcg      360

aacucauuag caacgccucc gacgcacugg auaagaucag guugaucagc cugacggacg      420

agaaugcccu cuccgguaac gaagaacuga cugugaagau uaaaugcgau aaggagaaaa      480

aucuguugca cguaaccgac accggggugg gcaugacucg ggaggagcuc gucaagaacc      540

ugggcaccau cgcgaaaagu gggacgagcg aguuccugaa uaagaugacu gaggcccagg      600

aagaugguca auccaccagc gagcucauug gccaguuugg ggugggcuuc uauagugcau      660

uucugguggc cgacaaaguc aucgugacuu ccaagcauaa caaugacacc cagcacauuu      720

gggaaagcga uuccaacgag uucaguguaa ucgccgaccc ccgcgguaau accuugggga      780

ggggcacgac uauuacccug gugcucaagg aggaagcaag cgauuaccug gagcuggaca      840

cuaucaaaaa cuuggucaag aaauauuccc aguuuaucaa uuucccaauu uacgugugga      900

gcaguaagac cgaaaccgug gaggaaccga uggaggagga agaggccgcg aaagaagaga      960

aggaggaauc cgaugacgag gccgcagucg aagaggaaga ggaggaaaag aaacccaaga     1020

cuaaaaaggu ggagaaaacg guaugggauu gggaacucau gaacgacauc aagccaauuu     1080

ggcaacggcc cagcaaggag guggaagagg augaguauaa agccuuuuac aagaguuucu     1140

ccaaagaaag cgacgaucca auggcauaua uccauuucac cgccgagggc gaagucacuu     1200

uuaagagcau ucuguucgug cccaccuccg ccccacgcgg gcuguuugac gaguacggua     1260

guaaaaagag cgacuacauc aagcucuaug ucaggcgggu guucaucacc gaugacuuuc     1320

acgauaugau gccgaaauac cugaacuucg ugaagggcgu aguggacucc gaugacuugc     1380

cccugaaugu cagccgcgaa acucuccagc agcauaaacu gcugaaggug auuaggaaaa     1440

aguugguccg gaaaacgcuc gauaugauca agaagauugc ggacgauaaa uauaacgaca     1500

ccuuuuggaa ggaguucggg acuaauauca aacugggcgu gauugaggau cacaguaacc     1560

gcaccaggcu ggcaaagcuc cugcgguuuc aguccagcca ccauccaacc gacaucacuu     1620

ccuuggauca auacguggaa aggaugaaag agaagcagga caagaucuau uucauggccg     1680

guaguagccg caaagaagcc gaguccagcc ccuuuguaga gcggcugcuc aagaaaggcu     1740

acgaagugau uuaucugacg gagccagucg acgaauacug uauccaggca cugcccgagu     1800

ucgaugggaa gagguuucaa aauguggcca aagaaggcgu caaguucgac gagagugaga     1860

agaccaaaga aucccgcgag gcgguggaaa aggaguucga accguugcug aacuggauga     1920

aagauaaggc ccucaaagac aagauugaga aagcaguggu aagccagcgg cugacugagu     1980

cccccugcgc ccucgucgca agucaguacg gguggagcgg uaauauggaa aggaucauga     2040

aggcccaggc cuaucaaacc ggcaaggaua uuuccacuaa cuacuaugca agccagaaaa     2100

agaccuuuga gaucaaucca cgccaccccc ugauucggga cauguugagg cggaucaaag     2160

aagaugagga cgauaagacg gugcuggacc ucgccguggu ccuguucgag accgcgacuc     2220

ugcgcagugg guacuugcug ccagauacca aagccuaugg cgacaggauc gaacggaugc     2280

uccgccuguc ccucaacauu gaccccgaug caaaggugga ggaagaacca gaagaggagc     2340

cggaagagac ugccgaagac accacggagg auaccgaaca ggacgaggau gaggaaaugg     2400

acguggguac ugaugaggaa gaggaaaccg ccaaggagag cacugcagag aaagacgaac     2460

ugugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  3310
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt7)

<400>  3310
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

gggagcugcg ggcacuccug uuguggggcc gcaggcugcg gccccuccug cgcgccccag      120

cguuggccgc agugcccggg gguaagccga uccugugccc aaggcggacc acugcccagc      180

ucggcccccg caggaaccca gcauggagcc ugcaagccgg gcggcuguuc uccacccaga      240

cggcggaaga caaagaggaa ccccuccaca guauuaucag cuccacugag aguguccagg      300

gcagcaccuc caagcaugaa uuucaggccg agaccaaaaa gcuguuggau auuguggcac      360

gcagccugua cuccgagaaa gaaguauuca ucagggagcu cauuaguaau gccagcgacg      420

cccuggaaaa gcugcggcac aaguuggugu ccgaugguca agcacuccca gagauggaga      480

uccaucugca gacuaacgcc gaaaaaggga ccaucacgau ucaggacacu ggcaucggca      540

ugacccagga ggaacugguc agcaaucucg ggacuauugc gcgcaguggu uccaaggccu      600

uucuggaugc auugcaaaac caggccgagg caagcuccaa aaucauuggc caguucgggg      660

ugggcuuuua uagugccuuc augguggccg acagggucga aguguacagc cgguccgcgg      720

caccggguag ccugggguau caguggcuca gugauggcuc cggcguauuu gagaucgccg      780

aggccagcgg ggugcgcacc gguaccaaga uuaucaucca ccugaaaagu gacuguaagg      840

aguucuccag cgaggcaagg guccgggaug uggugacgaa auacagcaau uuugucuccu      900

ucccccugua uuugaacggc cgcaggauga auacucucca agccauuugg augauggacc      960

caaaggaugu gcgggaaugg cagcaugagg aauuuuacag guauguagcg caggcccacg     1020

acaagccccg cuacacccug cacuacaaaa cugaugcacc acugaacauc cggaguauuu     1080

ucuaugugcc cgacaugaag ccgagcaugu ucgacgucuc cagggagcuc gggagcagug     1140

uggcccugua cucccgcaaa guguugaucc aaaccaaggc aaccgauauu cugcccaaau     1200

ggcuccgguu uaucaggggc gucguggaca gcgaggauau cccacugaau cugucccgcg     1260

aauugcucca ggagagugcc cugauucgga agcugaggga cguacuccag cagcggcuga     1320

ucaaguucuu uauugaucaa agcaaaaagg acgccgaaaa auaugcaaag uucuuugagg     1380

auuacgguuu guucaugcgc gaaggcaucg ugacugccac ggagcaggag gucaaagaag     1440

acauugcgaa gcugcucagg uaugagucca gcgcccugcc cagugggcag cugaccuccu     1500

ugagcgaaua cgcaucccgg augcgcgccg gcacuaggaa caucuauuac cugugcgccc     1560

caaaucggca ucucgcagag cacagucccu acuaugaggc gaugaagaaa aaggauaccg     1620

aagugcuguu uuguuucgag caguuugacg aacucacccu guugcaucug cgcgaguucg     1680

auaaaaagaa acucaucagc gucgaaacug acauuguggu ggaccacuac aaggaggaga     1740

aguuugaaga uaggucccca gccgcagagu gccugagcga aaaagagacg gaagaacuga     1800

uggccuggau gcggaacgua uuggggagua gggugaccaa ugucaaggug acucugcgcc     1860

ucgacaccca cccggccaug gucaccgugc uggagauggg ugcagcccgg cauuuccuca     1920

ggaugcaaca gcuggcgaaa acucaggagg aacgcgccca guugcugcaa cccacgcugg     1980

aaaucaaccc acggcacgca cucauuaaga aacugaauca guugagggcc uccgagcccg     2040

gccuggccca gcuccuggug gaucagaucu augaaaacgc aaugauugcc gcggggcucg     2100

uagacgaucc acgcgccaug gugggccggc ugaacgaguu gcuggucaag gcacuggaga     2160

ggcauugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  3311
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt7)

<400>  3311
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

agaucagcuc ccugcccacc caacucuuca aaugcuguuu uugcgacuuc cugaagguga      120

aaaugcacac uaugaguagc ucccauuugu uuuaccuggc ccucugucug uugaccuuca      180

cgaguagcgc aacugccggg ccagagaccc ugugcggugc ggaacucguc gaugcccugc      240

aguuugugug uggcgacagg ggguucuauu uuaacaagcc gaccggcuac gguuccagcu      300

cccggcgcgc accccagacu gggauuguag augagugcug uuucaggagu ugcgaccugc      360

ggcgccucga aauguauugu gccccacuga aacccgcaaa gagcgccagg uccgugcggg      420

cgcagcgcca caccgauaug ccaaagacgc agaaagaggu ccauuugaag aaugccagca      480

ggggcagugc aggcaacaaa aauuaccgga ugugaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  3312
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt7)

<400>  3312
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

uccccauggg uaagagcaug cuggugcucc ugaccuucuu ggccuuugca uccugcugua      120

uugccgcgua caggccaagu gagacucugu gcgggggcga acucgucgac acccugcagu      180

ucgugugugg ggaucggggc uuuuauuuca gccgcccggc cuccagggua agucggcgca      240

gcagggguau cguggaggaa ugcuguuuuc gguccugcga cuuggcacug cucgagacgu      300

acugugccac ucccgcaaaa agcgaacgcg augucuccac cccacccacc gugcugccag      360

acaacuuccc cagguaucca guggggaagu uuuuccaaua cgauacuugg aaacagagua      420

cccagcggcu gcgcaggggc cucccggccc uguugcgggc gcgcaggggc cacguccugg      480

ccaaggagcu cgaggcauuu cgggaagcca aacgccauag gccccugauu gcccugccaa      540

cgcaggaccc cgcacacggg ggugccccac ccgagauggc gagcaaucgg aagugaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  3313
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt7)

<400>  3313
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaca       60

gcuucuccac cagugccuuu ggccccgugg cauucagccu ggggcuccug uugguccugc      120

cagccgcguu uccggccccc gugccacccg gugaggacuc caaggaugua gcagccccac      180

acaggcagcc ccucaccagu agcgaacgga ucgacaaaca aauucgcuac auccuggaug      240

gcauuuccgc auugaggaag gagacuugca auaaaagcaa caugugugaa uccaguaagg      300

aggcccuggc ggaaaauaac cucaaucugc caaaaauggc cgagaaggac gggugcuucc      360

agagcggcuu uaacgaggaa acgugucugg ugaagaucau uacuggucuc cuggaguucg      420

aagucuauuu ggaguaccug cagaaucggu uugaguccag cgaagaacag gcacgcgccg      480

ugcaaaugag uaccaaagug cucauccagu uccugcagaa gaaagccaag aaccuggaug      540

caaucaccac uccggacccc accacgaaug ccuccuugcu cacuaaacug caggcgcaaa      600

accaguggcu gcaggauaug accacucauc ucauucugag gagcuuuaag gaguucuugc      660

aguccagucu gcgggcccuc cgccaaaugu gaggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  3314
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt7)

<400>  3314
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ugcucuggcu gaggggcuuc uugcuggcca gcugcuggau cauugugcgg uccaguccaa      120

ccccggggag cgagggucac uccgcagccc ccgacugucc aaguugcgcg cucgccgcac      180

ugcccaagga ugucccaaac agccagcccg aaauggugga ggccgugaaa aagcauaucu      240

ugaauaugcu gcaccucaaa aagcgcccag acguaacuca accggucccc aaagcagccc      300

ugcugaacgc gauuaggaag cuccaugugg gcaagguggg ggaaaauggc uacgucgaga      360

ucgaagauga cauuggucgg cgcgccgaga ugaacgagcu gauggaacag accuccgaga      420

ucaucacguu ugcagaaagc gggacugcca ggaaaaccuu gcacuucgag auuuccaagg      480

agggcaguga ucugagcgug guagaacggg ccgaggugug gcucuuucug aaagucccaa      540

aggcaaaucg caccaggacu aaagugacca uccggcuguu ccagcagcaa aagcaucccc      600

agggcuccuu ggacacgggg gaagaggccg aagagguggg ucucaaaggc gagcgcagcg      660

aacugcugcu cagugagaag gucguggaug cgaggaaguc cacuuggcac guauuuccag      720

ugagcuccag uauucagcgg cuguuggacc aggggaaaag cucccuggau guccgcaucg      780

ccugugaaca augccaggag agcggcgcaa gucucgugcu gcuggguaag aaaaagaaaa      840

aggaagagga gggggaaggc aagaaaaagg gcggggguga gggcggggcc ggcgcagacg      900

aagagaaaga acagucccac aggcccuucu ugaugcucca ggcccggcaa agcgaggauc      960

auccgcaccg caggcggcgc aggggucugg agugugacgg caaggugaac auuugcugua     1020

aaaagcaguu uuucgucagu uuuaaggaua ucggguggaa ugacuggauu aucgcccccu     1080

ccggcuauca ugcgaacuac ugcgaagggg aguguccaag ccacaucgca gguaccagcg     1140

gcuccagucu gagcuuccac uccacuguga uuaaucauua ucggaugagg gggcacagcc     1200

ccuuugccaa ccucaaaagu ugcugcguac caaccaagcu gcgccccaug uccauguugu     1260

acuaugacga uggccagaau aucauuaaaa aggacaucca aaacaugauu guggaagagu     1320

gugguugcag cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  3315
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt7)

<400>  3315
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacg       60

gccugcccgg gagggcccuc ggugcagccu gccuguugcu gcucgcggcc ggcuggcugg      120

ggccagaggc auggggcagc ccgacucccc cacccacccc agccgcaccc ccaccgcccc      180

cacccccagg uucccccggg ggcagucagg auaccuguac gagcugcggc ggguuccggc      240

gcccggaaga guuggguagg guggacggcg auuuucugga agccgucaag cggcacaucc      300

ucucccgccu gcaaaugagg gggcggccca acauuacuca ugcggugcca aaagccgcaa      360

ugguaaccgc ccugcgcaag cuccacgccg gcaaagugag ggaggacggu cgggucgaaa      420

ucccccaucu ggaugggcac gcaaguccag gcgccgacgg ccaggagcgc gugagcgaga      480

uuaucuccuu cgcggaaacc gauggguugg ccagcuccag ggugcggcug uacuuuuuca      540

uuaguaauga ggguaaccag aaucucuuug ucgugcaggc aagccugugg cuguauuuga      600

agcuccugcc cuacguacug gaaaaaggcu cccgcaggaa ggugcggguc aagguguauu      660

uccaagagca ggggcauggc gaccgcugga acauggugga gaaaaggguc gaucucaagc      720

ggagcgguug gcacacuuuu ccacugaccg aagccaucca ggcauuguuc gagcgcggcg      780

aaaggcggcu gaaucucgac gugcagugug auaguugcca agagcuggcc guagugccgg      840

ucuuugugga ccccggggaa gagucccaca ggccauucgu ggucgugcag gcccgccugg      900

gcgauagccg gcauaggauc cgcaaacggg gguuggagug ugacgguagg acgaaccucu      960

gcugucgcca gcaguuuuuc auugacuucc ggcugaucgg cuggaaugau uggauuaucg     1020

cgcccacugg guacuauggc aacuacugcg aagguuccug uccagcauau cuggccggcg     1080

uacccgggag ugccagcucc uuucacaccg caguggucaa ucaauacagg augcggggcc     1140

ucaacccggg gacugugaau agcugcugca uuccaaccaa gcugaguacc auguccaugu     1200

uguacuucga cgaugaguau aacaucguca aacgcgacgu gcccaauaug auuguggaag     1260

aguguggcug cgccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  3316
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt7)

<400>  3316
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ugagggugcu ccuguugacc gcacugacuc ucugccacgg cuucaaccug gacaccgaga      120

augccaugac guuucaggaa aacgcgcggg gguucgguca aagcgucgug caguugcagg      180

gcucccgcgu aguggucggg gcgccccagg agaucguggc agccaaucaa aggggcaguc      240

uguaccagug ugauuauagc acugguuccu gcgaaccaau ucggcuccag gugccggucg      300

aggcagugaa caugagucug gggcugagcc ucgccgcgac caccucccca ccccagcugu      360

uggccugugg ccccacugua caucaaaccu gcagcgaaaa uacguacgug aagggccugu      420

guuuucucuu cggguccaac cugcgccagc agccacagaa auuucccgag gcacugaggg      480

guugcccaca agaggacagu gauaucgccu ucuugauuga cggcagcggg uccaucauuc      540

cgcacgauuu ucggcgcaug aaggaguucg ucagcacugu gauggaacag cucaaaaaga      600

guaaaacccu guuuucccug augcaguaua gcgaagaguu caggauccau uuuacuuuca      660

aggaguucca aaauaacccc aauccacggu cccucgugaa gcccaucacc cagcuguugg      720

gccgcaccca cacggccacu gguauuagga aagucgugcg ggaacuguuu aacaucacca      780

auggggcacg caagaacgcc uucaaaauuc ucguagugau cacugacggc gagaaguuug      840

gcgauccacu gggguacgaa gacgucauuc ccgaggcgga uagggaaggu gugauccggu      900

augugauugg cgucggggac gccuuccgca gugagaaaag caggcaggag cugaauacca      960

ucgcauccaa gccgccccgg gaucaugugu uucagguaaa caauuucgaa gccuugaaaa     1020

ccauccaaaa ccagcuccgc gagaagauuu uugcaaucga aggcacucag acggguagca     1080

guuccagcuu cgagcacgaa augagucagg agggcuuuuc cgccgccauu accagcaacg     1140

ggccacugcu gagcacugug ggcuccuacg acugggccgg gggugucuuc cucuauacca     1200

guaaggagaa aagcaccuuu aucaauauga cuagggugga uuccgacaug aacgacgcau     1260

accugggcua cgccgccgca auuaucuugc ggaauagggu ccaaagccug gugcucgggg     1320

cgccccgcua ucagcacauc ggccuggugg ccauguuccg gcagaacacg gguauguggg     1380

aaaguaaugc caacguaaag ggcacccaga uuggggcaua cuuuggcgcc ucccugugua     1440

gcguggaugu cgacuccaau gggaguacug auuuggugcu caucggcgca ccacauuauu     1500

acgagcaaac cagggguggg caggucagcg ugugcccccu gccacgcggc cgggccaggu     1560

ggcaguguga cgccgugcug uauggugaac agggccaacc gugggggcgc uucggcgcag     1620

cccucaccgu acugggggau gugaacggcg acaaauugac ugaugucgcg auuggugccc     1680

ccggggagga agacaaucgg ggcgcagugu accuguucca cggcacgucc gggagcggua     1740

ucaguccauc ccauagccag aggauugccg gcuccaagcu caguccccgg cugcaguauu     1800

uugggcaaag ccuguccggc ggucaggauu ugaccaugga cgggcugguc gaucucacug     1860

ugggcgccca gggccacgug cugcuccugc gcagccagcc aguauugagg gucaaagcaa     1920

ucauggaguu caacccccgg gagguggcgc gcaauguguu ugaaugcaac gaccaagucg     1980

ugaaggggaa ggaggccggu gaagugaggg uaugccugca cguccagaaa aguacccggg     2040

accgccucag ggagggccag auccaguccg uggugacuua cgaucuggca cuggacagcg     2100

ggcggccgca uuccagggcc gucuucaaug agaccaagaa cagcacgcgc cggcaaaccc     2160

agguguuggg ccugacucag accugugaaa cucucaaacu gcagcuccca aauugcauug     2220

aggaucccgu aagucccauc gugcugaggu ugaacuuuag ccuggucggu accccacugu     2280

ccgccuucgg gaaccuccgc cccgugcugg cagaagacgc ccaacgguug uuuacggcgc     2340

uguucccauu ugagaagaau uguggcaacg auaauauuug ccaggacgau cucaguauca     2400

ccuucagcuu uaugucccug gacugucucg uggucggcgg gccgagggag uucaacguga     2460

cuguaaccgu gcgcaaugau ggugaagaca gcuaccggac ucaggucacc uucuuuuucc     2520

cccuggauuu guccuauagg aaagugagua cgcugcaaaa ccagcgcagc cagcgguccu     2580

ggaggcuggc cugcgagagu gcaagcucca ccgaagugag cggcgcccuc aagaguacuu     2640

ccuguagcau uaaucaccca aucuuucccg agaacuccga agucaccuuc aauauuacuu     2700

uugacgugga uagcaaggcc agucugggga acaaauugcu gcucaaggca aauguaaccu     2760

ccgagaacaa uaugccacgc acgaacaaaa ccgaguucca gcuggaacug cccgugaagu     2820

acgccgucua uaugguggug acuagccaug gcgucaguac caaauaccuc aauuuuacug     2880

cguccgagaa caccagccgg gugaugcaac accaguauca gguauccaac cugggucaga     2940

ggagcuugcc gaucagucug guguuccucg ucccagugcg ccugaaucaa acugugaucu     3000

gggaccggcc ccaggucacc uuuagcgaaa acuuguccag uacgugccau accaaggaga     3060

ggcugccaag ccacuccgac uuccucgccg aacugcgcaa ggcacccgug guaaauugua     3120

gcauugccgu gugccagagg auccagugcg auauuccguu uuucgggauc caagaggaau     3180

uuaacgcaac ucugaaaggc aaucucuccu ucgacuggua cauuaagacc agucacaacc     3240

aucuguugau cgucagcacu gccgagaucc uguucaauga uuccguguuu acccuccugc     3300

ccggccaggg ggcguucgug cggagccaga cggagaccaa agucgaacca uuugaggugc     3360

ccaacccauu gccccugauu guagguaguu ccgugggcgg gcuccugcug cucgcccuga     3420

ucacugcagc cuuguauaag cugggcuucu uuaaaaggca guacaaggac augaugagcg     3480

aagguggccc accgggggcc gagccccaau gaggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  3317
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt7)

<400>  3317
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguuca       60

gccugaagac ccuccccuuu cuguugcugc uccacgugca gaucuccaaa gccuucccag      120

ucaguagcaa ggagaaaaac acuaagaccg ugcaagacua ccuggaaaaa uuuuaucagu      180

ugccguccaa ucaguaccag aguacgagga agaacggcac uaauguaauu guggagaagc      240

ugaaagaaau gcaacgguuc uuugggcuca acgucaccgg uaagcccaau gaggaaaccc      300

uggauaugau gaaaaagcca cgcugcggcg ugcccgacag cgggggcuuc augcugacuc      360

cagguaaccc caaaugggag aggaccaauc ucacguaucg gauccgcaac uacacuccac      420

agcuguccga ggcagaagug gagagggcca uuaaggaugc guuugaauug uggagcgucg      480

ccuccccgcu gaucuucacc cggauuaguc agggggaggc agacaucaau aucgccuuuu      540

aucagcgcga ucauggcgac aacagccccu ucgauggccc aaaugggauu cucgcacacg      600

ccuuucaacc cggucagggc aucgggggcg acgcgcauuu cgaugccgag gaaacuugga      660

ccaacaccuc cgcaaauuac aaccuguucc ugguggccgc ccacgaguuu ggucauagcu      720

uggggcucgc acacaguucc gacccaggcg cccugaugua ucccaauuac gcguucaggg      780

aaacgagcaa cuacucccug ccgcaggaug acauugaugg cauccaggcc auuuaugggc      840

ucaguagcaa ccccauccaa ccaacugguc ccuccacccc aaaacccugu gacccaagcc      900

ugacuuuuga cgcaauuacc accuugcggg gcgagauccu guucuuuaag gaucgcuacu      960

ucuggaggcg gcacccgcag cuccagcgcg uagaaaugaa uuuuaucagu cuguucuggc     1020

ccucccugcc aacugggauu caagccgcau augaggacuu ugauagggac uugaucuucc     1080

ucuuuaaggg caaccaguac ugggcccuga gcgguuauga uauucugcag ggcuacccca     1140

aagacaucag uaauuauggg uucccaucca gcgugcaggc cauugaugcg gcagucuuuu     1200

accggagcaa gacguacuuc uucgugaacg accaauuuug gcgcuaugau aaucagaggc     1260

aguucaugga gcccggcuac ccgaaaucca ucaguggggc cuuuccaggu aucgaaagca     1320

agguggacgc cgucuuccag caagagcacu uuuuccaugu guuuuccggc ccccgguauu     1380

acgcauucga ucucauugcc cagcgcguaa ccaggguggc gcgggggaac aaauggcuga     1440

auugcaggua uggcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  3318
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt7)

<400>  3318
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

uguggcagcc ccucgugcug gucuugcugg ugcucggcug cuguuucgcc gcaccaaggc      120

aacggcaguc cacccuggua uuguuuccgg gggaccugcg cacuaaccuc accgauaggc      180

agcuggccga ggaauaccug uaucgguacg guuauacgcg cguggcggag augaggggcg      240

aaaguaagag ccucgggccc gcccuguugc ugcuccagaa acaacugucc cugccagaga      300

cuggcgaauu ggacagugca acccucaagg ccaugcggac ccccaggugc ggugucccag      360

aucuggggag guuccagacu uuugagggcg accugaaaug gcaccaucac aauaucaccu      420

acuggauuca gaacuauagc gaggaucucc cccgggcagu gaucgacgau gccuucgcgc      480

gcgccuuugc acuguggucc gccgugacgc cauugacuuu caccaggguc uacagccggg      540

acgccgauau ugugauccag uuuggcguag cagaacaugg ggacgguuau ccguucgaug      600

gcaaggacgg gcugcucgcc cacgcguuuc ccccaggccc cgguauucaa ggggaugccc      660

auuucgacga cgaugagcug uggucccugg gcaaaggcgu ggucgugcca acucgcuuug      720

ggaaugcaga cggugccgca ugucacuucc ccuucaucuu ugaaggcagg aguuacagcg      780

ccugcaccac cgaugggcgg uccgacggcu ugccguggug uagcacgacu gccaacuacg      840

auaccgacga ucgcuucggu uuuugcccca gugagaggcu cuauacucag gacggcaaug      900

cggaugggaa gccaugucag uuccccuuua ucuuccaggg ccaauccuac agcgcaugca      960

ccaccgacgg gcgguccgau gguuaucgcu ggugugccac uacggccaac uacgacaggg     1020

acaagcuguu uggcuucugc ccaacccggg cagauaguac ugugaugggc gggaauagcg     1080

ccggugagcu gugcgucuuu cccuucaccu uucucggcaa agaauauucc accuguacua     1140

gcgaggggag gggcgacggg cgccuguggu gcgcgacgac caguaacuuc gauuccgaca     1200

agaaaugggg cuuuugucca gaucaggguu acagcuuguu ccugguggcc gcacacgagu     1260

ucgggcaugc ccucggccug gaccacaguu ccguaccgga agcacugaug uaucccaugu     1320

accgguuuac ugaaggucca cccuugcaua aggaugacgu gaauggcauu aggcaccucu     1380

acgggccacg ccccgagccg gagccacggc cacccaccac cacuacgccc cagcccaccg     1440

ccccaccgac ugucugcccc accggcccac ccacugugca cccaagcgaa aggcccaccg     1500

ccgggccgac gggcccaccc agcgcagguc caaccgggcc cccgacugcc ggccccucca     1560

ccgcgacuac cgugccacug agucccgucg augacgccug uaacgugaau aucuucgaug     1620

caauugccga gaucggcaac caacuguauc ucuuuaaaga cgggaaguac uggcgcuuca     1680

gcgaaggucg gggcuccagg ccacaggggc ccuuucugau ugccgauaaa uggccagcau     1740

ugccgcggaa gcuggacagc guauucgagg aacgccucag uaagaaacug uuuuucuuuu     1800

ccggccgcca gguguggguc uauacgggug cgagcgugcu ggggccccgg cgcuuggaca     1860

agcugggccu cggcgccgau gucgcacagg ugaccggggc ccugaggucc ggucggggca     1920

aaaugcuccu guucaguggg cgcagguugu ggcgguuuga cgugaaggcc caaaugguag     1980

auccaaggag cgcauccgag guggaccgca uguuccccgg cgucccacug gauacucaug     2040

acguguucca guaccgggag aaagccuauu uuugccagga uagguucuac uggcgcguca     2100

gcagucgguc cgaacucaau cagguggacc aaguggguua uguaaccuac gauauccugc     2160

agugucccga ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  3319
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt7)

<400>  3319
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ccggcgugcu ggccgcauuc cucuuucuga gcuggaccca uugcagggcc uugccacugc      120

cguccggggg ugacgaggau gaccucagug aagaggaucu gcaguucgcg gaacgguacu      180

ugcgcagcua uuaccacccc acuaaccugg ccggcauccu caaggagaau gcagccucca      240

guaugaccga aaggcugcgg gagaugcaga gcuuuuucgg gcuggagguc acgggcaaac      300

ucgacgauaa cacucuggac gugaugaaga aaccacgcug ugguguaccc gauguggggg      360

aauauaaugu cuuuccaagg accuugaagu gguccaaaau gaaccugacc uaccggauug      420

ugaauuauac ucccgacaug acccauagcg agguggaaaa ggcauucaag aaagccuuua      480

aggucugguc cgaugugacg ccacucaacu ucacucgccu gcacgacggc aucgcggaua      540

uuaugaucag uuuuggcauu aaagagcaug gggacuucua cccguuugau ggucccagcg      600

gccuguuggc ccacgcauuc ccacccgggc caaauuaugg cggugacgcc cacuucgacg      660

augacgagac cuggacuucc agcaguaagg gguacaaccu cuuucuggua gccgcacaug      720

aguucggcca cucccugggc cucgaucaua gcaaagaccc cggggcccug auguuuccga      780

ucuacaccua uaccgguaag ucccacuuca uguugcccga ugacgaugug caaggcaucc      840

agagucugua cgggccaggc gacgaggauc ccaauccaaa acaccccaag acgccagaca      900

agugcgaucc gagccucucc cuggacgcga uuacuagccu gaggggugaa accaugaucu      960

uuaaagaccg guucuuuugg cgcuugcauc cccagcaagu cgaugccgaa cucuuccuga     1020

cuaagaguuu uuggccagaa cugcccaaca ggauugacgc agccuaugag cacccauccc     1080

augaucucau cuucauuuuu cggggccgca aauucugggc acugaauggg uacgacaucu     1140

uggagggcua ucccaagaaa auuagcgaac uggggcuccc gaaggaggug aagaaaauca     1200

gugccgccgu gcacuuugaa gauaccggua agacccugcu guucuccggc aaccaggucu     1260

ggagguacga cgauacuaau cauaucaugg acaaagauua uccacgguug auugaggaag     1320

acuuccccgg gaucggcgau aagguggacg cgguauacga gaaaaacggu uacauuuacu     1380

uuuucaaugg ccccauccag uuugaguaua gcauuuggag caaccgcauc gugaggguca     1440

ugccagcaaa cuccauccuc ugguguugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3320
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt7)

<400>  3320
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

cccccaacac uaccgaagac uacgauacga cuaccgaguu cgacuauggc gaugccaccc      120

caugccagaa ggugaaugaa agggcauuug gggcccaacu gcucccgccc cuguacagcu      180

uggucuucgu gaucggucug guaggcaaca uucucguggu ccugguguug gugcaguaua      240

aacggcugaa gaauaugacu uccaucuacc uccugaaccu ggcgauuagu gaccuccugu      300

uuuuguucac ccugccauuu uggaucgauu auaaacucaa ggacgauugg gucuucgggg      360

acgccaugug uaaaauucug agcggcuuuu acuauacggg ucuguacucc gagaucuucu      420

uuaucauuuu gcucacuauc gaucgcuacc uggcaauugu gcacgccgua uucgcacuga      480

gggcccggac cgugacuuuu ggggucauca ccaguauuau cauuugggcg cucgccaucc      540

uggcaagcau gcccggcuug uauuucucca agacccagug ggaauuuacg caucacacuu      600

gcagccugca uuuuccacac gagucccucc gcgaguggaa gcuguuccag gcccugaaau      660

ugaaucucuu uggccuggug cugccccucc uggugaugau cauuuguuac accgggauca      720

uuaagaucuu gcugaggcgg ccaaacgaga aaaagaguaa agccguccgc cucauuuucg      780

ugaucaugau cauuuucuuc cuguuuugga cuccguauaa ucugaccauc uugauuagcg      840

uauuccaaga cuuucucuuc acccaugaau gcgaacaguc caggcaccug gaucuggcag      900

ugcaggucac ugaggugauc gccuacacgc acuguugcgu gaaccccguc auuuaugcgu      960

uuguggguga gcgguuccgc aaguaccuca ggcagcuguu ucaucggcgc guagccgugc     1020

acuuggucaa auggcugcca uuccucagcg uggacaggcu ggaacggguc aguuccacca     1080

gccccuccac uggcgagcau gaacugagug caggguucug aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  3321
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt7)

<400>  3321
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagga       60

cccuggccug ccuccuguug cugggcugug gguaccucgc acacgugcug gccgaggaag      120

cggagauccc ccgggaaguc auugagcgcu uggccaggag ccagauccau uccauucggg      180

accugcaacg ccuccuggaa aucgauagug uggguagcga ggacucccug gauaccaguc      240

ucagggcaca cggcguacau gccacuaagc acgugccaga gaaacggccg cugcccauuc      300

gcaggaagcg gagcaucgaa gaggcagucc cagccgugug caaaacgcgc acugugaucu      360

augaaauucc caggucccag gucgacccaa ccagcgcgaa cuucuugauc uggcccccau      420

guguggaggu aaagcggugc accggguguu gcaauacuuc cagugugaaa ugucagccga      480

gccgcgucca ucacaggucc gugaaggugg ccaaggucga guacgugcgg aaaaagccca      540

aacugaagga aguacaggug cgccucgagg aacaccugga gugcgcaugu gccaccacga      600

gccugaaccc agauuauagg gaagaggaca cuggccggcc ccgcgagagu gguaaaaaga      660

ggaaacggaa gagguugaag ccaaccugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  3322
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt7)

<400>  3322
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaca       60

ggugcugggc ccuguuccuc agccuguguu gcuacuugcg gcuggugucc gcagagggcg      120

accccauccc agaggaacuc uaugaaaugc ugagugauca cagcauucgc uccuuugacg      180

auuugcagag gcugcuccau ggggacccgg gugaggaaga uggcgccgag cuggaccuga      240

auaugacccg gagucacagc gggggcgagc ucgaaucccu ggcgcgcggu aggcggagcu      300

uggggucccu gacuaucgcc gagcccgcaa ugauugccga auguaagacc cgcacggagg      360

ucuucgagau caguaggcgg cucauugauc gcacuaacgc aaauuuucug guguggccac      420

ccugcguaga agugcaaagg uguagcggcu gcuguaacaa ucggaacguc cagugccgcc      480

caacccaggu gcagcugagg cccgugcaag uccggaaaau cgagaucgug cgcaagaaac      540

caauuuucaa gaaagccacc guaacuuugg aagaccaucu cgcguguaag ugcgagaccg      600

uggccgcagc caggccgguc acgcgguccc ccggcgggag ccaggaacag cgcgccaaga      660

cuccacagac cagggugacu auccggaccg ugaggguccg ccggccccca aaagguaagc      720

acaggaaauu uaagcauacc cacgauaaaa cggcacugaa ggagacucug ggcgccugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  3323
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt7)

<400>  3323
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

uguucggccu ccuguugcug accuccgccc ucgcagggca gaggcaaggu acucaggccg      120

agaguaaccu gagcuccaag uuucaguuca guagcaauaa agaacagaac ggcgugcaag      180

acccccagca cgagcggauc auuaccgucu ccacgaaugg gagcauccau uccccacgcu      240

uuccgcacac uuaccccagg aacaccgugu ugguauggcg gcugguggcg gucgaagaga      300

auguguggau ucagcucacc uucgaugaac gcuuuggccu ggaggaccca gaggaugaca      360

ucugcaagua ugauuucgug gaagucgagg aacccaguga cgguacuauu cuggggaggu      420

gguguggcag cggcaccgug ccagggaaac agaucuccaa ggguaaccaa auccggauuc      480

gcuuuguaag cgaugaguac uuccccagug agccaggcuu uugcauccau uauaauauug      540

ugaugccgca guucacggaa gccgucuccc ccagcgugcu cccacccucc gcacugccau      600

uggaccugcu caacaaugcc aucacugcau uuaguacccu ggaggaucug auuagguacu      660

uggaacccga gcgguggcag cucgaccugg aagaucugua ucgcccgacu uggcagcucc      720

uggggaaagc cuucguguuc ggcaggaaaa gccgggucgu ggacuugaac cugcucaccg      780

aggagguacg ccuguacucc uguaccccca ggaauuuuag cgugaguauc cgggaggaac      840

ugaagcgcac ggauacuauu uucuggccag guugcuugcu cgucaagagg ugugggggca      900

acugcgcgug uugccugcac aauuguaacg aaugccaaug cgugcccucc aaggugacca      960

aaaaguauca ugagguccug cagcuccggc caaaaacugg cgugcgcggg cugcacaaga     1020

gcuugaccga cguagcccug gaacaccaug aggaguguga cugcgugugu agggguagua     1080

ccggcgggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  3324
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt7)

<400>  3324
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

ggcugaucuu cguguacacc cucauuugcg ccaacuuuug uagcugccgg gacacuuccg      120

caacgcccca gagugccagc aucaaggcgc ugcgcaaugc caacuugagg cgggaugacc      180

uguaucgcag ggaugagacc auucaaguca aaggcaaugg guacgugcag uccccacggu      240

ucccgaacag uuauccccgc aaucuccugu ugacuuggag gcugcauagc caggaaaaca      300

cccggaucca gcucguauuu gacaaucaau ucggucugga ggaagcagag aacgauauuu      360

gucgcuacga cuuuguggaa gucgaggaua ucuccgagac cagcacuauc auuaggggcc      420

gguggugcgg gcacaaggaa gugccacccc gcaucaaauc caggaccaau cagauuaaga      480

ucacguucaa aagugacgau uauuuugugg ccaagccagg cuucaagauu uacuauagcc      540

ugcucgagga cuuucagccc gcagccgcgu ccgaaacuaa cugggagagc gucaccaguu      600

ccaucagcgg uguguccuac aauaguccaa gcguaacuga uccgacccug auugccgacg      660

cauuggauaa aaagaucgcc gaguucgaca ccguggaaga ccugcucaaa uacuuuaacc      720

ccgaguccug gcaggaagau cuggagaaua uguaucugga cacgccacgg uaccgcggga      780

ggagcuauca ugaucggaag aguaaagucg acuuggaucg ccucaacgac gaugccaaga      840

gguacuccug uacuccccgg aauuauagcg ugaacaucag ggaggaacug aaacuggcaa      900

acguggucuu cuucccacgc ugccuccugg ugcaacggug uggcggcaau ugcgggugug      960

guaccguaaa cuggaggagu ugcacuugca auuccggcaa gaccgugaag aaauaccacg     1020

aggucuugca guuugaaccc gggcauauua agcgccgggg cagggccaaa accauggcgc     1080

ugguggacau ccagcucgau caccacgagc gcugugacug cauuuguagc agccggccgc     1140

ccaggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  3325
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt7)

<400>  3325
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguga       60

cccacagcaa guuccccgcc gcaggcaugu ccaggccacu ggacaccagu cuccggcuga      120

aaacuuuuag cuccaagagu gaguaccagu uggucgugaa cgccguacgc aaacugcaag      180

aaagcggguu cuauuggucc gcggugacgg guggcgaggc caaucuccug uugagcgcag      240

aaccggccgg gacuuuucug aucagggauu ccagugacca gcggcauuuc uuuacccuca      300

gcgucaagac ccaguccggc acuaaaaacc ugcgcauuca gugcgagggu gggagcuuca      360

gucugcaauc cgaucccagg agcacccagc cagugccccg guuugacugu gugcucaagc      420

ugguccacca uuacaugcca cccccaggcg caccguccuu ccccagucca cccacggaac      480

caagcuccga ggugcccgag cagccgagcg cccagcccuu gccaggcagu cccccacgca      540

gggcguauua caucuauucc gggggugaaa agauuccccu gguacucagc cggccacuga      600

guuccaaugu ggccacucug caacacuugu gccgcaaaac cgucaacggc caucucgaua      660

gcuacgagaa ggugacucag cugccggggc ccaucaggga auuucuggac caguaugaug      720

caccacucug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  3326
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt7)

<400>  3326
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugc       60

ccagcgccgg ccagcuggca cucuucgccc uggggaucgu cuuggcggcc ugccaagcac      120

uggagaacuc caccagucca cucagcgccg acccgcccgu ggcagccgcg guaguguccc      180

acuuuaauga uuguccagac agucauacuc aguucugcuu ucacgguacc uguagguucc      240

ugguccagga agauaagccc gccugcgugu gucauagcgg cuacgugggg gcacggugcg      300

agcacgccga cuugcuggcc gucguggcag ccucccagaa aaagcaagcg auuacggccc      360

ucguaguggu cagcaucgug gcacuggccg ugcugauuau cacuuguguc cucauucauu      420

gcugucaggu gcgcaaacac ugcgaauggu gcagggcacu gaucugucgg cacgagaagc      480

cauccgccuu gcugaaaggc cgcaccgccu gcugucauag ugaaaccgua gugugaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  3327
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt7)

<400>  3327
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

caagcggccu gaggcuccug ccguugcugc ucccccuguu guggcugcuc gugcugaccc      120

cagggcggcc cgccgcaggu cuguccacuu gcaagaccau cgacauggag cucgucaaac      180

gcaagaggau ugaagccauc cggggccaga uucugaguaa auugcgccug gcgagcccac      240

ccucccaagg ggaggugcca ccgggccccc ucccagaagc cguacuggca cuguacaaca      300

guacgaggga ucggguggcc ggugagagcg cagaacccga gccagagccc gaagccgacu      360

auuacgcgaa ggaggucacu cgcguguuga ugguggaaac ccacaaugag aucuaugaua      420

aauucaagca guccacccau agcauuuaca uguuuuucaa cacuuccgag cucagggaag      480

ccgucccgga gcccgugcug cugagucggg cagaacuccg ccuguugagg cugaagcuca      540

aaguagagca gcacguggaa cuguaucaga aguacagcaa uaacuccugg cgguaucuga      600

gcaaucgcuu gcucgcccca agugacuccc ccgaguggcu gagcuuugau gucaccgggg      660

uggugaggca auggcugucc cggggcggcg agaucgaagg guuccgccuc agugcccauu      720

guagcugcga cuccagggau aacacgcugc aggucgacau caaugguuuu acuaccggcc      780

ggcgcgggga uuuggcaacu auucacggca ugaacaggcc auuccugcuc cugauggcca      840

cgccccugga gcgggcgcag cauuugcaga gcaguaggca ccgccgggcc cucgacacca      900

auuacuguuu uuccagcacc gagaaaaacu gcugugugag gcaacuguac aucgauuucc      960

gcaaggaccu ggguuggaaa uggauucacg aaccaaaggg guaucaugca aauuuuugcc     1020

ucggcccgug ucccuacauc uggagucugg auacucagua uuccaaagua uuggcccugu     1080

acaaccagca caauccaggc gcaagcgccg cccccugcug ugugccacag gcgcucgaac     1140

cccugccgau ugucuauuac guggggcgga agccaaaggu ggagcaacug agcaacauga     1200

ucgucagguc cugcaaaugc aguugaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  3328
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt7)

<400>  3328
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugcgugcu gagcgccuuc cucauccugc auuuggucac cguggcacug ucccucagua      120

cuuguagcac ccuggacaug gaucaguuua ugaggaagcg gauugaggcc auccgcggcc      180

aaauuuuguc caaacugaag cucacgaguc ccccagaaga cuauccggag cccgaagagg      240

uaccacccga agugaucagc auuuacaacu ccacuaggga ucugcugcag gagaaagcga      300

gccggcgcgc cgcagccugc gagagggaac gguccgacga ggaauauuac gcaaaggagg      360

ucuauaaaau cgauaugcca cccuucuuuc caagugagaa ugccaucccg cccaccuucu      420

accgcccaua uuuuaggauu gugcgguucg acgugagcgc gauggaaaag aacgccucca      480

aucucgucaa ggcagaguuu cgcguguuca ggcugcagaa ccccaaagcc cggguaccag      540

aacagcgcau cgaguuguac caaauucuca agagcaaaga ucugaccagu cccacucaga      600

gguacaucga cuccaaggug gucaaaaccc gggccgaagg ggaguggcug agcuuugaug      660

ugacggacgc agugcacgag uggcugcauc acaaggaucg caauuugggu uucaaaauuu      720

cccuccauug uccgugcugu acuuuugucc ccaguaacaa uuauaucauu ccaaacaaga      780

gcgaggaacu ggaagccagg uucgcgggca ucgacgggac cuccacuuac accagcggcg      840

aucagaagac caucaaaagu acgcggaaga aaaauuccgg uaagacuccc caucugcucc      900

ugauguugcu gccaagcuau cgccucgaga gucagcaaac caacaggcgg aaaaagaggg      960

cccuggacgc agccuacugc uuccgcaaug ugcaggacaa cuguugccug cggcccuugu     1020

auauugauuu uaagagggac cucgggugga aauggaucca cgaaccaaag ggcuacaaug     1080

caaacuucug ugccggcgcc ugcccguauc ugugguccag cgauacucag cacagccgcg     1140

uacugucccu cuacaauacc auuaaccccg aggcgagugc aagcccaugc uguguguccc     1200

aggaccugga gcccuugacc auccuguacu auauugggaa aacuccaaag aucgaacaac     1260

ucagcaacau gaucgucaaa aguugcaagu guuccugagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  3329
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt7)

<400>  3329
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

ugcaucugca gagggcccuc gugguccugg cauugcugaa cuucgccacc gugagccucu      120

cccugaguac uugcaccacg uuggacuuug gccacaucaa aaagaaacgg guagaggcga      180

uucgcgggca aauccugagc aagcucaggc ugacuucccc acccgaaccg accgugauga      240

cccacguccc cuaccaggug cuggcccucu auaauaguac ucgggagcug uuggaagaga      300

ugcaugguga acgcgaggag ggcuguaccc aggaaaacac ggagagcgaa uacuaugcaa      360

aagagauuca caaguucgau augauccagg ggcuggccga gcauaaugaa cucgcagugu      420

gcccaaaggg cauuacuucc aaagucuuua gguucaacgu gagcuccgua gagaagaauc      480

ggaccaaccu guuucgcgcc gaguucaggg ugcugcgggu ccccaaucca aguagcaaac      540

gcaacgaaca aaggaucgaa uuguuucaga uccuccggcc cgacgagcac auugcgaagc      600

agcgcuacau cggugggaaa aaucugccaa cuaggggcac cgccgagugg cuguccuucg      660

augugaccga cacggugcgg gaauggcucc ugcgcaggga gagcaacuug ggccuggaaa      720

uuaguaucca cuguccgugc cauacuuuuc agcccaaugg ggauauucuc gagaacaucc      780

acgaagucau ggagauuaag uucaaaggug uggacaauga ggaugaccau ggccgcgggg      840

aucugggccg gcugaagaag caaaaagacc accacaaccc acauuugauc cucaugauga      900

uucccccaca caggcuggau aaucccgguc aagggggcca gcggaagaaa agggcacugg      960

acaccaacua uuguuuucgc aaccucgaag agaauugcug uguacggccg cuguacaucg     1020

auuucaggca ggacuugggc uggaaguggg ugcaugaacc caaaggguau uacgccaacu     1080

ucugcuccgg uccauguccc uaccugcgca gcgccgacac uacccacucc accguccucg     1140

gccuguauaa uacucugaac ccagaggcaa gugccagccc cugcugcgug ccacaggauu     1200

uggaaccgcu cacgauccug uacuaugugg ggcggacccc caaggucgag cagcugucca     1260

auaugguggu aaagagcugu aaaugcaguu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3330
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt7)

<400>  3330
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

ccguggcagu cugggccgcg cuggccgugg gccucgagcu gugggcagcc gcacacgccu      120

ugccagcgca gguagccuuc accccguacg cacccgaacc agggagcacu ugcaggcugc      180

gggaguauua cgaccaaacc gcccagaugu guugcuccaa guguaguccc ggucagcaug      240

ccaaaguguu uugcacgaag acuagcgaua ccgucuguga cuccugcgaa gauaguaccu      300

auacucagcu cuggaacugg gugccagagu gucugagcug cggcucccgc uguagcuccg      360

accaagugga aacccaggca ugcacgaggg agcagaaucg gaucugcacu ugucgccccg      420

ggugguacug cgccuugagu aaacaggagg gcuguaggcu gugcgcgcca cuccggaagu      480

gucgcccggg uuucgggguc gccaggcccg gcaccgaaac uagcgaugug guaugcaaac      540

caugugcacc cggcaccuuu uccaacacca cgagcaguac ugacauuugc cggccacacc      600

aaaucuguaa uguggucgcc auucccggga acgcauccau ggaugccgug ugcaccagca      660

cuuccccgac ccgcaguaug gcccccggug cggugcaucu gccacagccc gucagcacca      720

ggucccagca cacucagcca acgcccgagc caagcaccgc accgaguacu uccuuccugc      780

uccccauggg cccaaguccc ccagccgaag ggagcaccgg cgacuuugcc cugcccgugg      840

guuugaucgu aggggugacc gcacugggcc uccugauuau cggcgucgug aauugcguga      900

ucaugacuca agucaagaag aaaccgcugu guuugcagcg ggaggccaag gugccacauc      960

uccccgcgga uaaagcccgc gggacgcagg gucccgagca acagcaucug cugauuaccg     1020

caccauccag cagcuccagu agccucgaau ccagcgccag ugcacuggac aggcgggccc     1080

ccacucgcaa ccagccacag gccccgggcg uagaggcauc cggggccggc gaagcgaggg     1140

ccagcaccgg uuccagugau agcucccccg gcgggcacgg cacccaagug aaugucacuu     1200

gcaucgugaa cgucuguagc aguuccgacc acagcuccca gugcaguagc caggcaucca     1260

gcacgauggg ggauaccgac aguuccccaa gcgagucccc caaggacgaa caggugccau     1320

ucagcaaaga ggagugugcc uuucggaguc aauuggaaac ucccgagacc cugcucggua     1380

gcacugaaga gaagccgcug ccacugggcg ugcccgaugc cgggaugaaa ccauccugag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  3331
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt7)

<400>  3331
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

ugaugaggcu guucccaugc uuucuccagc uguuggccgg ccuggcacuc ccggccgugc      120

ccccacaaca gugggcgcug agcgccggga acgguuccag ugaggucgaa guagugcccu      180

uccaggaggu cuggggccgg agcuacuguc gcgcauugga aaggcuggug gacguggucu      240

ccgaguaucc aagugaagug gagcacaugu uuagccccuc cugcguaagc cuccugcggu      300

guaccgggug cuguggcgau gagaaucugc auugcgugcc agucgaaacu gccaacguga      360

ccaugcagcu ccugaagauc cgcuccggug acaggccgag uuacguggag uugacguuca      420

gccaacacgu ccggugugaa ugccgccccc ugagggagaa aaugaagcca gagcggcgca      480

ggcccaaagg gcggggcaag cgcaggcggg aaaaacagcg cccaacugau ugucaucucu      540

gcggcgacgc agugcccagg cggugaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  3332
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt7)

<400>  3332
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

acaggcagac ugauaccgcc cccagcccau ccuaccaucu gcucccgggc cggcgcagga      120

cgguggacgc agccgcgagu cgggggcaag gucccgagcc agcccccggc gggggcgucg      180

aagguguggg ggcacgcggc guagcccuga aguuguucgu gcagcugcuc ggcugcagca      240

gguuuggggg ugcagucgug cgggccggcg aggcggaacc auccggggcc gcacgcagug      300

ccagcuccgg cagggaggaa ccccagccag aggaggguga agaggaagag gagaaagaag      360

aggaacgggg gccgcagugg cgccugggcg ccaggaagcc cggcagcugg acuggggagg      420

cagccgugug ugcggauucc gccccagcag cccgggcacc ccaagccuug gcccgcgcga      480

gugguagggg cgggcggguc gcacgcaggg gcgccgaaga gagcggucca ccccacuccc      540

cgagccggcg cggcagugcc uccagggcag ggcccggccg ggccagcgag accaugaacu      600

uccugcucuc cugggugcac uggagucugg cgcugcuccu guauuugcau cacgccaaau      660

ggagccaggc agccccaaug gcagaagggg guggccagaa ucaucacgag guagugaagu      720

uuauggacgu cuaccagagg uccuauugcc accccaucga aacccuggug gauauuuucc      780

aagaguaccc agacgaaauc gaguauauuu uuaaacccag cugugugcca cucaugcgcu      840

gcgggggcug uugcaacgau gagggucugg aauguguccc gacugaggaa aguaauauca      900

ccaugcagau uaugcggauc aagccccauc agggccagca caucggggag auguccuucc      960

ugcaacauaa caagugcgaa uguaggccca aaaaggaccg cgcccggcag gagaaaaaga     1020

gcgugagggg caaagggaag ggccagaaac gcaagcggaa gaaaaguagg uacaaguccu     1080

ggagcguaua ugugggugcc cggugcugcu ugaugccaug gagccuccca gggccccacc     1140

cguguggccc augcuccgag cgcaggaaac accuguuugu ccaagauccc cagacgugua     1200

agugcaguug uaaaaauacu gacagccggu gcaaggcacg ccagcuggaa cucaacgaga     1260

ggaccugucg gugcgauaag cccaggcgcu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3333
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt7)

<400>  3333
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugcucag cugggugcac uggucccugg ccuugcugcu cuaccugcau cacgcaaagu      120

ggagucaggc cgcgcccaug gccgagggcg ggggucaaaa ucaucacgaa gucgugaaau      180

uuauggacgu auaucagagg agcuacugcc auccaaucga gaccuuggug gauauuuucc      240

aggaauaucc ggacgagauc gaauacauuu uuaagcccuc cuguguccca cugaugcggu      300

gcggcgggug uugcaacgau gagggccucg agugugugcc cacugaagag aguaauauca      360

ccaugcagau uaugcgcauc aaaccacacc aaggucagca caucggggaa augagcuucc      420

ugcagcauaa caagugcgag uguaggccca aaaaggaccg ggcacgccag gagaagaaau      480

ccgugagggg caagggcaaa gggcaaaagc ggaaacgcaa gaaaagcagg uauaaguccu      540

ggagugucua cgugggugcc cggugcuguc ugaugccaug gagccucccg ggcccccacc      600

caugcgggcc cugcuccgaa cgcaggaagc aucuguuugu acaggaucca cagacgugua      660

aaugcagcug uaagaauacu gacagucggu gcaaagcacg ccaguuggag cugaacgaaa      720

ggaccugucg gugcgauaag cccaggcgcu gaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  3334
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt7)

<400>  3334
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

cccugcucag gcggcuguug cuggccgcac uccugcaguu ggccccagcg caagccccgg      120

ugucccagcc cgacgcacca ggccaccagc gcaaggucgu gaguuggauc gauguauaca      180

ccagggccac uugccagccc cgggaggugg ucgugccacu gaccguggaa cucaugggga      240

cggucgcaaa acaacuggug cccagcugug uaacugugca gcgcugcggu ggcuguugcc      300

cagacgaugg gcuggagugu gucccgaccg gccagcauca ggugaggaug caaauucuca      360

ugauccggua ucccuccagu cagcugggug aaaugagcuu ggaggaacac ucccagugcg      420

agugucgccc aaagaaaaag gacagcgccg ugaaacccga uagggcggcc accccacauc      480

accggcccca gccgcgcucc guccccgggu gggacagugc accaggcgcc cccagcccag      540

ccgauauuac ucaucccacc ccagcaccgg gccccuccgc ccacgcggcc ccaagcacga      600

ccagugcacu gacucccggg ccagccgcag ccgccgcgga cgcagccgcc uccagcgugg      660

caaagggugg cgccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  3335
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt7)

<400>  3335
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcauc       60

ugcucggcuu cuuuagcgug gccugcuccc uguuggcagc cgcgcugcuc cccgggccaa      120

gggaggcccc ggcagccgca gccgcguucg aaaguggucu ggacuugagc gaugccgagc      180

ccgacgcagg cgaagccacc gccuacgcau ccaaggaucu ggaggaacag cuccggagug      240

ucagcuccgu ggacgagcug augacuguac uguauccaga guacuggaaa auguauaagu      300

gucaacuccg caaagggggc uggcagcaca acagggaaca ggccaaucug aacagccgga      360

ccgaggaaac gaucaaguuu gcggccgcac acuacaauac ugagauuuug aaauccaucg      420

auaacgagug gcgcaagacc cagugcaugc ccagggaagu guguauugac gucgguaagg      480

aguucggggu ggccaccaau acuuucuuca aaccacccug cgugaguguc uaucggugug      540

gcggcugcug uaacagcgaa gggcugcaau gcaugaauac cuccacgagc uaccucagua      600

agacucuguu ugagaucacc gugccacugu cccagggucc gaaacccgua acuauuagcu      660

ucgcaaacca uaccuccugu cgcugcauga guaaguugga uguguauagg cagguccaca      720

gcaucauccg gcgcucccuc ccagccaccc ugccccagug ccaagccgcg aauaaaacgu      780

guccaacuaa cuacaugugg aauaaccaua uuuguaggug ccuggcacag gaagacuuua      840

uguucagcag ugaugccggc gacgauucca ccgacggguu ucacgauauc ugcggcccca      900

auaaggagcu cgacgaggaa acuugucagu gcgugugucg ggccggucug cgcccggcaa      960

gcugcgggcc ccacaaagag uuggacagga acaguuguca gugcgugugc aagaauaagc     1020

uguucccauc ccaauguggc gccaaccggg aauuugauga gaauaccugc cagugugucu     1080

gcaaacgcac cugucccagg aaccagccac ucaaccccgg caagugcgcg ugugaaugca     1140

cugagagccc acaaaaaugu cugcugaagg ggaaaaaguu ucaucaccag acgugcagcu     1200

guuaccggcg cccgugcacc aauaggcaga aggccugcga gcccgguuuc uccuauagug     1260

aagaggugug ucggugcgua ccaagcuacu ggaaaaggcc ccagaugucc ugaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  3336
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt7)

<400>  3336
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguaca       60

gggagugggu ggucgugaac guauucauga ugcuguaugu gcagcucguc caaggcagcu      120

ccaaugaaca cgggcccgug aagcggagua gccaguccac ccuggagcgc agugaacagc      180

agaucagggc cgcaagcucc uuggaggaac ugcuccggau uacucauagc gaggacugga      240

aacuguggcg cugcagguug cggcugaagu ccuuuaccag uauggauagc cgcuccgcca      300

gccacaggag uacgcgguuc gcggccacuu uuuacgacau cgagacccuc aaagugauug      360

augaagagug gcaacgcacc caguguuccc caagggaaac uugcgucgag guggcaagcg      420

agcuggguaa guccaccaac acguucuuua aaccgcccug uguaaaugug uuccggugcg      480

gcggguguug caacgaagag agucugaucu guaugaauac uagcaccucc uauauuagca      540

agcagcucuu ugaaaucagu gucccacuga cuuccgugcc cgaguuggug ccagucaagg      600

uggccaacca uaccggcugc aaaugucugc ccaccgcacc acgccacccg uacagcauca      660

uuaggcggag uauccagauu cccgaagagg accgcugcuc ccauagcaag aaacucugcc      720

caaucgauau gcugugggac agcaauaagu guaaaugcgu acugcaagag gaaaaccccu      780

uggccgguac ggaggaucac ucccaccucc aggaaccagc gcuguguggg ccccauauga      840

uguucgacga ggauaggugc gaaugugugu gcaagacucc gugucccaaa gaccugauuc      900

agcacccaaa gaauugcagu uguuuugagu gcaaggagag ccucgaaacc ugcugucaga      960

aacauaagcu guuccacccc gauacuugcu ccugugagga ccggugccca uuucacaccc     1020

gccccugugc cagcggcaaa accgcaugcg ccaagcauug uagguuccca aaagaaaagc     1080

gggccgcaca aggcccgcac aguaggaaga accccugagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  3337
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt8)

<400>  3337
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

ccgacgaaac cggcuucgaa cacuccggcc ucugggucuc cguccucgcc ggccuacuac      120

uaggcgccug ccaagcccac cccauccccg acucaucccc acuucuacaa uucggcggac      180

aagucagaca acgauaccuc uacaccgacg acgcccaaca aacagaagcc caucucgaaa      240

uaagagaaga cggcaccguc ggcggcgccg ccgaccaauc ccccgaaucc cuacuccaac      300

ucaaagcacu caaacccggc gucauccaaa uccucggcgu caaaaccucc cgcuuccuau      360

gccaacgccc cgacggcgcc uuauacggcu cccuacacuu cgaccccgaa gccugcucuu      420

uucgcgaacu ccuacucgaa gacggcuaca acguauacca auccgaagcc cacggccuac      480

cccuacaccu ccccggcaac aaaucacccc accgcgaccc agccccacgu ggccccgcac      540

gcuuccuccc acuaccaggc cucccacccg cccuccccga accacccggc auccucgcac      600

cccaaccacc cgacguaggc uccucagacc cccucuccau ggucggcccc ucccaaggcc      660

gcucacccuc auacgccuca uaaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  3338
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt8)

<400>  3338
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

ccuucccacc ccuccuccua cuucucuucu ggggcguagu aucccacucc uuccccgcca      120

cacuagaaac ccaagaacaa gacguagacc ugguccaaaa auaccuagaa aaauacuaca      180

accucaagaa cgauggacga caagucgaaa aacgccgcaa cuccggcccg gucguagaaa      240

agcuaaaaca aaugcaagag uucuucggcc uaaaagucac uggcaaacca gacgccgaaa      300

cccucaaagu caugaaacaa ccacgaugcg gcgucccaga cgucgcacaa uucguccuca      360

cagaaggcaa cccccgaugg gaacaaaccc accucaccua ccgaauugaa aacuacacac      420

cugaccugcc cagagccgac guagaccacg ccauagaaaa agccuuucaa cucuggucaa      480

acgucacacc ccucaccuuu accaaagucu cggaaggcca agccgacaua augauuagcu      540

ucguucgagg cgaccacaga gacaacuccc ccuucgacgg acccggcggc aaccucgccc      600

acgccuucca acccggcccg gguauaggcg gagaugcaca uuucgacgaa gacgaacgcu      660

ggacaaacaa cuucagagaa uacaaccucc accguguagc agcccacgaa cuaggccacu      720

cacucggacu cucacacagc accgacaucg gagcccuaau guacccaucc uacacuuucu      780

ccggagacgu ucaacucgcc caagacgaca ucgacggcau ccaagcaauc uacggccgcu      840

cccaaaaccc aguacaaccc aucggaccac agacucccaa agccugcgac uccaaacuca      900

ccuuugacgc aaucaccacc auccgaggcg aagucauguu cuucaaagac cgcuucuaca      960

ugcgcacgaa ccccuucuac ccagaagucg aacucaacuu cauaucaguc uucuggcccc     1020

aacuaccaaa cggccuugaa gcagcauacg aauuugccga cagagacgaa guccgcuucu     1080

ucaaaggaaa caaauacugg gccguccaag gccaaaacgu ccuucacggc uaccccaagg     1140

acauauacuc cuccuucggc uucccccgaa cagucaaaca caucgacgcg gcacuguccg     1200

aagaaaauac cggcaagaca uacuucuucg ucgccaacaa auacuggcgg uacgacgaau     1260

acaaacgauc cauggacccc ggcuacccca aaaugauagc acacgacuuc ccgggaaucg     1320

gccacaaagu cgaugcagua uucaugaaag acggauucuu cuacuucuuc cacggcacac     1380

gccaauacaa auucgacccc aaaacaaaac gcauccucac ccuccagaaa gccaacagcu     1440

gguucaauug ccgcaaaaac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  3339
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt8)

<400>  3339
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

ccuucccucc ccuacuacuc cuacuauucu ggggagucgu aucacacucc uucguccuca      120

ccgaaggcaa cccucgaugg gaacaaaccc accucacuua ccgaaucgag aacuacaccc      180

ccgaccuccc acgagccgac gucgaccacg ccaucgaaaa agccuuucaa cuauggucca      240

acgucacacc ccucaccuuc acuaaaguaa gcgaaggcca agccgacauc augaucagcu      300

ucguccgcgg agaccaccga gacaauuccc ccuucgacgg cccaggaggc aaccuagccc      360

acgccuuuca accaggaccc ggcauaggag gcgacgccca cuucgacgaa gacgaacgau      420

ggacaaacaa cuuccgcgaa uacaaccucc acagaguagc cgcccacgaa uuaggccacu      480

cccuaggacu cucacacuca accgacauag gugcccucau guaccccucc uacaccuuca      540

gcggcgacgu ccaacuagcc caagacgaca ucgacggcau acaggccauc uacggccgau      600

cucaaaaucc aguccaaccc auaggaccac agacaccaaa agccugugac uccaaacuca      660

ccuucgacgc caucaccacc auacgcggag aagucauguu cuuuaaagac agauucuaca      720

ugcguaccaa ccccuucuac ccagaaguag aacuaaacuu cauaucuguc uucuggccac      780

aacuccccaa cggccuagaa gcagcauacg aauuugcuga cagagacgaa guacgauucu      840

ucaaaggcaa caaauacugg gccguccaag gccaaaacgu acuacacggc uacccaaaag      900

acaucuacuc cuccuucggc uucccccgca cagucaaaca caucgaugcc gcacucagcg      960

aagaaaacac cggaaaaacc uacuucuucg ucgccaacaa auacuggcga uacgaugaau     1020

acaaacgauc cauggacccc ggauacccca aaaugaucgc ccacgacuuc cccggaauag     1080

gccacaaagu cgacgcaguu uucaugaaag acggcuucuu cuacuucuuc cacggaacca     1140

gacaauacaa auucgacccc aaaaccaaac gcauccucac ccuccaaaaa gccaacuccu     1200

gguucaacug ccgcaaaaac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  3340
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt8)

<400>  3340
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

aaaacauccu caaaauacuc auggacucgu auucuaagga auccaaaauc caaaccguca      120

gacgcgucac uagcgucucc cuccucgcgg uguaccuaac uaugaauacg uccagccuag      180

uccucgcaaa gccuaucgag aacaccaacg acaccagcau uaaaaacguu gagaagcuac      240

gcaacgcgcc aaacgaggaa aacucaaaga aagucgaaga cagcaaaaau gacaaaguag      300

agcacguuaa aaacauagaa gaagccaagg uggaacaagu agcaccggaa gucaaaagca      360

aaaguacccu acgcagcgcc agcauugcca acaccaacag cgaaaaguac gacuucgagu      420

aucuuaacgg gcucagcuac acagaacuaa caaaccugau caaaaacaua aaauggaacc      480

aaauaaacgg uuuguucaac uacagcacag ggucacaaaa auucuucggc gauaaaaacc      540

gcguccaggc caucauaaac gcccuacaag aaagcggccg cacauacacc gcgaacgaca      600

ugaagggaau agaaaccuuc acggagguau uaagggcggg guucuaccua ggcuacuaca      660

augacggacu cucauaccua aacgaccgca acuuccaaga caagugcauc cccgccauga      720

uagccauaca gaaaaaccca aauuuuaaac ucggcacggc cguccaagac gaaguuauaa      780

cauccuuagg gaaacucauc ggaaacgccu cggccaacgc cgaaguggug aacaacugcg      840

uccccguacu uaagcaauuc cgcgaaaacc uaaaccaaua cgcacccgac uacguuaagg      900

ggaccgcggu caacgaauug auaaaaggaa ucgaguucga cuuuagcgga gcagcauaug      960

aaaaggacgu gaagacaaug cccugguacg gcaagauuga uccguucauu aacgaacuca     1020

aggcccucgg acuauacgga aacauaaccu cagcaaccga gugggcuuca gauguaggca     1080

ucuacuaccu gagcaaguuc ggccuauaca gcaccaaccg caacgacauu gugcaaaguu     1140

uagaaaaagc agucgacaug uacaaguacg gcaagauugc auuuguagcg auggaacgaa     1200

uaacguggga cuacgacggc aucggcucca acggaaagaa agucgaccac gacaaguucc     1260

uggaugacgc cgagaagcac uaccucccca agacauacac cuucgacaac ggcaccuuca     1320

ucauccgagc cggcgacaaa guaucggaag aaaagaucaa gagacuauac ugggccucca     1380

gagaagucaa aucccaauuc caccgagucg ucggaaacga caaggcccua gaaguaggaa     1440

acgccgacga cguauuaacu augaaaauuu uuaacagccc agaagaauac aaauucaaca     1500

ccaauauuaa cggcguauca acagacaacg gaggacugua cauagaaccc cgagggacau     1560

ucuacacaua cgaacggacc ccacaacaau ccaucuuuag ccuggaagaa cucuucagac     1620

acgaauacac ccacuaccua caggccagau accuagucga cgguuuaugg ggacaaggcc     1680

ccuucuacga gaaaaaccga cucacauggu uugacgaggg cacagccgag uucuucgcag     1740

gaucaacaag aaccagcggc gugcucccgc gaaagucgau ccuuggcuau uuagcgaaag     1800

acaaaguaga ccacagauac agccuaaaga aaacacugaa cucaggcuac gacgauagcg     1860

acuggauguu cuacaacuau ggcuucgcag uagcgcacua ccuuuacgaa aaagacaugc     1920

cgacguucau caagaugaac aaagcaauac uaaacaccga cguuaaaucg uacgacgaaa     1980

uaaucaaaaa gcuguccgac gaugccaaca aaaacacaga auaccaaaac cauauccagg     2040

aacucgcgga caaguaccag ggggcaggaa ucccccuagu cucggacgac uaccuaaaag     2100

accacggcua caagaaagca agcgaaguau acagugagau cagcaaagcc gccucccuaa     2160

cgaacacauc agugacugcu gagaaaagcc aguacuucaa caccuucaca cuccgaggaa     2220

cuuacacggg agaaacauca aaaggcgagu ucaaagacug ggacgaaaug agcaagaaau     2280

uagacggcac ccuagaauca cuagcgaaaa acucuuggag cggauacaag acccuuaccg     2340

cauacuucac gaacuacagg gucaccagug acaacaaagu gcaguacgac gucguguucc     2400

acggaguucu aacagacaac gccgacaucu ccaauaacaa agcaccaauc gccaagguga     2460

cggggccaag cacaggagcc gucggacgaa acauagaguu cucaggcaaa gacagcaagg     2520

acgaagacgg gaagauagua aguuacgacu gggacuucgg ugacggagca acaucccgcg     2580

guaagaacag ugugcacgca uauaagaagg ccggaacaua caacguaacc cuaaagguaa     2640

cggacgacaa aggagcgaca gcgaccgaau cguuuacuau cgaaauaaag aacgaagaca     2700

cgaccacucc aauaacaaaa gaaauggaac caaacgauga caucaaagaa gccaacggcc     2760

cuauagucga agguguaacc guaaaaggcg accucaacgg cuccgacgac gcagacacgu     2820

ucuacuucga cgugaaagaa gacggggacg uaacaaucga acuccccuac uccggcuccu     2880

caaacuucac cuggcuagua uacaaggaag gggacgauca aaaccacauc gcaagcggaa     2940

ucgauaaaaa caauaguaaa guagggaccu ucaaaucgac aaagggaagg cacuacgucu     3000

ucauuuacaa gcacgacagc gccagcaaca uaaguuacuc cuuaaacauc aaaggacuag     3060

gcaacgaaaa acuuaaggaa aaagagaaca acgacucaag cgacaaagcg acuguaaucc     3120

caaacuucaa uacgacaaug caagguuccc uccucggaga cgacucacgg gacuacuaca     3180

gcuucgaagu caaggaagaa ggcgaaguga acaucgaacu ggacaaaaag gacgaguucg     3240

gcguaaccug gacccugcac cccgaaagca acaucaacga caggaucacc uacggccaag     3300

uagacggcaa caaagucagc aacaaaguca aacuccgccc cggcaaguac uaccuacugg     3360

ucuacaagua cagcggcuca ggaaacuacg aacuccgcgu caacaaguaa ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  3341
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt8)

<400>  3341
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

gggucaccuu cauaagccuc cucuuucugu ucagcagcgc auacucaaua gccaacacca      120

acucagaaaa auacgacuuc gaauaccuaa acggccuaag cuacaccgaa cuaaccaacc      180

ucaucaaaaa cauaaaaugg aaccaaauaa acggccuauu caacuacagc accggcaguc      240

aaaaguucuu cggugacaag aaccgcgucc aggcgauaau caacgcccua caagaauccg      300

gccgcaccua cacagccaac gacaugaaag gcauagaaac auucacggaa guacuacgug      360

cuggauucua ucuaggcuau uauaacgacg gacugagcua ccuaaacgac aggaacuuuc      420

aagacaaaug cauccccgcc augauagcaa uccagaaaaa ucccaacuuu aaacucggaa      480

cggcggucca agacgaggug aucacgucac uuggaaaacu cauaggaaac gcgagcgcca      540

acgccgaggu aguaaauaac ugcguaccag uccugaagca auuccgugaa aaucuuaacc      600

aauacgcccc agacuacgua aaaggaacug cggucaacga gcucauaaaa ggaauagagu      660

ucgacuucag cggagccgca uaugaaaaag acguaaagac caugcccugg uacggcaaaa      720

uagacccguu caucaacgaa cucaaggcac uaggccuaua cggcaacauc acaagcgcca      780

ccgaaugggc cucagacguc gggaucuacu accuaucaaa auucggacuc uacagcacaa      840

accgaaacga caucguacaa ucccuagaaa aagcagucga cauguacaaa uacggaaaga      900

ucgcauucgu cgccauggag cgcaucacgu gggauuacga cggaauaggc ucaaacggaa      960

agaaagucga ccacgacaaa uuccucgacg acgcagaaaa acacuaccug ccgaaaacuu     1020

auacguuuga caacggcacc uucauuaucc gcgcgggcga caaaguaucu gaggaaaaga     1080

ucaaacgacu auacugggcu agccgagaag uaaaaagcca guuccaccga guagucggaa     1140

acgauaaggc gcucgaagua ggaaacgccg acgacguccu uacuaugaag aucuucaaca     1200

gccccgaaga auacaaauuc aacacuaaca ucaacggcgu auccacagac aacggaggcc     1260

uauacaucga accuaggggc accuucuaca ccuacgaacg caccccacaa caaucaaucu     1320

ucucucuuga agaacucuuc cggcacgagu acacccacua ccuacaagca cgauaccucg     1380

ucgacggccu auggggccaa ggaccauucu acgagaaaaa cagacucacc ugguuugacg     1440

aagggaccgc ugaguucuuc gccggcagca caagaacauc aggaguccuc ccccgaaaga     1500

gcauccuagg auaccuggcc aaggacaagg uagaucaccg cuacagccua aagaagacac     1560

uaaacagcgg cuacgacgac uccgacugga uguucuauaa uuacggcuuc gcgguagcac     1620

acuaccugua ugaaaaagac augccaaccu ucaucaaaau gaacaaagca auacuaaaca     1680

ccgaugucaa aagcuacgau gaaauuauca aaaagcugag cgacgacgca aauaaaaaca     1740

ccgaauauca aaaccacauc caggaacucg ccgacaaaua ccaaggcgca gggauccccc     1800

uggugucaga cgacuaccua aaagaccacg gcuacaagaa agccucggaa gucuacuccg     1860

aaaucaguaa agcagccagc cuaaccaaua caucaguuac agccgaaaag agccaguacu     1920

ucaacacauu cacacugagg ggcaccuaca caggcgaaac uuccaaaggg gaguucaagg     1980

acugggacga aaugagcaag aagcucgacg gcacccucga aucacucgcu aaaaauucau     2040

ggucgggaua caagacuuua acggcauacu ucacgaacua ccgagugaca agcgacaaca     2100

aaguccaaua cgacgucguc uuucacggcg uccugaccga caacgcagac auauccaaca     2160

acaaagcacc gaucgcaaaa gucaccggac cgagcaccgg ggcagucggg agaaacaucg     2220

aguucucagg caaagacucc aaggacgagg acggcaaaau cgucagcuac gacugggacu     2280

ucggagacgg cgcaacaagc cggggcaaga acucagucca cgccuacaag aaagcaggaa     2340

ccuacaacgu aacacuaaaa guaaccgacg acaaaggggc aacagccacc gaaucguuca     2400

ccauagaaau caaaaacgaa gacaccacca cccccauuac gaaagagaug gaaccgaaug     2460

acgacaucaa agaggcuaac ggcccuaucg ucgagggcgu aaccguaaaa ggcgaccuua     2520

acggaucgga ugacgcagac accuucuacu ucgacguaaa agaagauggc gacgucacua     2580

ucgagcuccc auacuccggc uccagcaacu ucaccuggcu cguauacaag gaaggugacg     2640

accagaacca caucgcuucg gggauagaca aaaauaacuc uaaaguuggc acauucaaga     2700

gcacaaaagg ccggcauuac guuuucauau acaagcacga cuccgcuuca aacaucaguu     2760

acagccucaa caucaaggga cugggaaaug agaagcucaa agagaaagag aacaacgacu     2820

ccuccgacaa agccacggua auacccaacu ucaauacgac caugcaaggu ucucuacucg     2880

gcgacgacag cagggacuac uacucguuug aggucaagga ggaaggcgaa guaaacauag     2940

agcuugacaa gaaagacgag uucgguguga cguggacacu acacccagag uccaacauaa     3000

augacagaau aacauacggc cagguagacg gcaacaaggu gagcaacaaa gucaaacucc     3060

gacccgguaa auacuaccua uuagucuaca aauacuccgg aagcgggaac uacgagcuac     3120

gcgucaauaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  3342
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt8)

<400>  3342
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

ggguaaccuu cauaucccuc cuguuccuau ucucaucagc auacagcaug aagaaaaaca      120

uccucaaaau ccuaauggau agcuacucaa aggaaaguaa aauccagacg guucgccgag      180

ugacguccgu cucccuucua gcaguauacc ucacuaugaa cacaagcucc cuaguccugg      240

ccaaacccau ugaaaacacc aacgacaccu cuauaaagaa cguagaaaaa cuccgaaacg      300

ccccaaacga ggaaaacuca aagaaaguag aggauucuaa aaacgacaaa guagaacacg      360

ucaaaaacau agaagaggcc aaaguagaac aagucgcccc ggaagucaaa uccaaaagca      420

cgcugcgguc ggcgucucgc cggcgacgga aacgcauagc aaacacaaac ucggaaaaau      480

acgacuucga auaccucaac ggacucagcu acaccgaacu gacgaaccuc aucaaaaaca      540

ucaaauggaa ccaaaucaac ggacuguuca acuacuccac aggaucccaa aaguucuucg      600

gcgacaaaaa ccgaguacag gcgaucauaa augcccugca ggaaagcggc agaacuuaua      660

ccgcaaauga caugaagggc aucgaaacgu ucaccgaggu ccugagagcg ggcuucuacc      720

uaggauacua caacgacgga cucagcuacc ucaacgaccg caacuuucag gauaaaugca      780

uaccggcaau gaucgcaauc cagaaaaacc ccaacuucaa acuuggaaca gcgguacaag      840

augaggucau cacaucgcug ggaaagcuaa uaggaaacgc cuccgcaaac gccgaaguag      900

ucaacaacug cgucccugua uuaaaacaau uccgugagaa ccucaaccaa uacgcccccg      960

acuacgucaa aggcaccgcc gucaacgaac ugauaaaggg cauagaguuc gacuucagug     1020

gagcagcaua cgaaaaagac gucaagacca ugcccuggua cggcaaaauc gaucccuuca     1080

ucaaugaacu caaagcgcuu ggccucuacg gaaacauaac cucugccaca gaaugggcaa     1140

gcgacgucgg aauauauuac cuauccaaau ucggccucua cagcacaaac agaaacgaca     1200

uaguacaguc acucgaaaaa gcugucgaca uguacaaaua cggaaagaua gcauucgucg     1260

caauggaacg cauaacaugg gacuacgacg gcauaggguc caacggcaag aaaguagacc     1320

augacaaguu ccuagacgac gcagaaaaac acuaccugcc caagaccuac accuucgaca     1380

acggaaccuu cauaauccga gcaggcgaca aaguaagcga agagaaaaua aaacgccuau     1440

acugggccag ucgagaaguc aaaucacaau uccaccgagu cguaggcaac gacaaggcac     1500

uagaaguggg aaacgccgac gauguccuaa cuaugaaaau cuucaacagc ccggaagaau     1560

acaaauucaa caccaacauc aacggggucu caaccgacaa cggcgggcug uacauagagc     1620

cgcgcggcac guucuacacg uacgagcgca caccccaaca aagcaucuuu ucgcuagaag     1680

aacuuuuccg acacgaauau acccacuacu uacaggcucg auaccucgua gauggccuau     1740

ggggccaagg cccauucuac gaaaagaaca gacucaccug guucgacgaa ggaaccgcag     1800

aguucuucgc aggaucgacc aggacgagcg gcguccuccc aaggaaaucc auacuuggau     1860

accucgcaaa agauaaggua gaccaccggu acucacuuaa aaagacucuc aacucaggau     1920

acgacgacuc cgacuggaug uucuacaacu acggcuuugc cguggcucac uaucuguacg     1980

aaaaggacau gcccaccuuc aucaagauga acaaagccau ccucaacacc gacguaaaaa     2040

gcuacgacga aauaaucaag aaacucucag acgacgcgaa uaaaaacaca gaauaccaaa     2100

aucacauaca agagcucgcc gacaaauacc agggcgcggg gauaccgcuc gucucugacg     2160

acuaccucaa agaccacggg uacaagaaag ccagcgaggu cuacagugaa aucagcaaag     2220

ccgccucgcu aaccaacacc agcguaacgg cggagaaaag ccaguacuuc aacaccuuca     2280

cacuaagagg aaccuauacc ggugagacca gcaaaggcga guucaaggac ugggacgaaa     2340

uguccaagaa auuagacggg acccuagaau cgcuggccaa aaacuccugg aguggguaua     2400

agacccuuac cgcguacuuc acaaacuaca gagugaccag cgacaauaaa guccaguacg     2460

augucguguu ccacggcgug cuaacagaca augcagacau cucaaacaac aaagccccaa     2520

ucgccaaagu cacgggaccc agcacaggcg ccguaggccg caacaucgaa uuuucaggua     2580

aggauucaaa agacgaagac ggcaagaucg ucagcuacga cugggacuuc ggagacggcg     2640

ccaccagcag agggaaaaac ucaguacacg cguacaagaa ggccgggacc uacaacguca     2700

cccuaaaagu uacggaugac aaaggcgcca cagccacgga auccuucacc auagaaauca     2760

agaacgagga cacaacuacc cccauaacca aagagaugga gccaaacgau gacauaaaag     2820

aagcuaacgg cccaaucgug gaaggcguua cugucaaagg ggaccuaaac ggcucagacg     2880

acgccgacac cuucuacuuu gacguaaaag aagacgggga cgucacaaua gaacucccau     2940

acuccggaag uagcaacuuc accuggcuag uguacaagga aggggaugau caaaaccaca     3000

uagcauccgg cauagacaag aacaacucaa aaguugggac cuucaaaucg accaaaggcc     3060

ggcacuacgu auucaucuac aaacacgacu ccgcaaguaa uauaucauac agccuaaaca     3120

uaaaggggcu gggaaaugaa aaacuuaagg aaaaagaaaa caacgacagu agcgacaaag     3180

caacagugau ccccaacuuc aauacaacca ugcaaggcuc acuccucgga gaugacucaa     3240

gggacuacua cucauucgaa gugaaggaag aaggcgaagu caacaucgaa cucgacaaga     3300

aggacgaguu cggcgucacc uggacccucc acccugaauc aaacauaaac gacaggauca     3360

ccuacggcca aguagacgga aacaaagugu caaacaaggu aaaacucaga ccggggaaau     3420

auuaccuacu gguguacaaa uauucuggaa gcggaaacua cgaacuacga gucaacaaau     3480

agggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  3343
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt8)

<400>  3343
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccucaaaau aauccuaaac cgaggcaaaa ccaugaagcg caaaugccuc agcaagagac      120

ucaugcucgc aaucaccaug gcuacaaucu ucacaguuaa cucaacucuc cccaucuacg      180

ccgcgguaga caaaaacaac gcaaccgccg ccguccaaaa ugaaucuaaa cgauacacag      240

ucagcuaccu aaaaacccuu aacuacuacg accucguaga ccugcucgug aaaaccgaaa      300

ucgagaaccu cccggaccug uuccaauauu ccagcgaugc caaagaguuc uacgggaaca      360

aaacacgaau gucguucauc auggacgaaa ucggacgccg agcgccccaa uacaccgaga      420

uugaucauaa gggaaucccg acgcucgucg aagucguccg agccggguuc uaucucggcu      480

uccacaacaa ggaacucaac gagauaaaca aacgcucuuu caaggaacgc gucauaccgu      540

ccauacuugc cauacagaaa aaccccaauu ucaagcucgg aacagaagua caagacaaaa      600

ucguauccgc caccggccug cuagccggaa acgaaaccgc accaccagaa gucgucaaca      660

acuucacucc cauccuucaa gacugcauca agaacaucga cagauaugca uuggacgacc      720

uaaaaucaaa agcacuguuc aacguucuag ccgcgcccac auaugauaua accgaauacc      780

ucagagcaac aaaggagaaa cccgaaaaca cucccuggua cggcaaaauc gacggcuuca      840

ucaacgaacu aaagaaacuc gcauuauacg gcaaaaucaa cgacaacaac aguuggauca      900

uagacaacgg cauauaccac aucgcgccac uaggaaaacu acacucuaac aacaaaaucg      960

gaaucgaaac acuaaccgaa gucaugaagg uauaccccua ccugagcaug caacaccuuc     1020

aaucugcaga ucaaaucaaa cgacacuacg acagcaaaga cgccgaggga aacaagaucc     1080

cauuagacaa auucaagaaa gaaggaaaag agaaauacug cccaaagacc uacacguuug     1140

augauggcaa aguaaucaua aaggccggcg cacgcgucga ggaagaaaaa gucaaacgcc     1200

uguacugggc gucaaaagaa gucaacuccc aauucuuccg agucuauggc aucgacaaac     1260

cccucgagga aggcaacccc gacgacauac ugacaauggu cauuuacaac ucgccugagg     1320

aauacaaacu gaacucagug cuauacggcu acgacaccaa caacggcggc auguacaucg     1380

aacccgaagg cacuuucuuc acuuacgaga gagaggccca agaauccacg uacacacuag     1440

aagaacuuuu ccgacacgag uacacccacu accuccaagg ccguuacgca gucccgggac     1500

aauggggacg aacgaaacuc uacgacaacg acaggcugac cugguacgaa gagggcgggg     1560

cggaacuauu cgcagggagc accaggacau cggggauacu ucccaggaaa uccaucgucu     1620

ccaacaucca caacacaaca cgaaauaauc gguauaaacu gagcgauacc guccacucaa     1680

aauacggcgc gucauucgag uucuacaacu acgccuguau guucauggac uacauguaca     1740

acaaagauau gggaauccuc aacaaauuaa acgaccucgc uaagaacaac gacguagacg     1800

gcuacgacaa cuacauaaga gaccuauccu caaacuacgc ucugaacgac aaauaccaag     1860

accacaugca ggaacgaauc gacaacuacg aaaaccucac cgucccguuc gucgccgacg     1920

acuaccucgu gagacacgcc uacaaaaacc ccaacgaaau cuacagcgag aucagcgaag     1980

ucgccaaacu caaggacgca aaauccgagg ucaaaaaguc ucaauacuuc agcaccuuca     2040

cucuacgcgg cucauacacg ggcggcgccu ccaaaggcaa auuagaagac caaaaagcca     2100

ugaacaaguu uaucgacgac agccucaaga aacuugacac cuacucgugg aguggcuaca     2160

aaacucuaac cgccuacuuu acaaacuaca aagucgacuc guccaaccgc gugacauacg     2220

acguagucuu ccacggguac cuaccgaacg agggagacag caaaaacagc cuccccuacg     2280

gaaaaauaaa cggcacauac aagggaaccg aaaaagagaa aauaaaauuc uccuccgaag     2340

gcucguucga ccccgauggu aagauaguau ccuacgaaug ggacuucgga gacggcaaua     2400

aaagcaauga ggaaaaccca gaacacucau acgacaaagu agggaccuac accguuaaau     2460

uaaaagucac ggacgacaaa ggagagucga gcgucucaac caccaccgcc gagauaaaag     2520

accuauccga aaacaaacua cccguaaucu auaugcacgu cccaaaauca ggcgcacuca     2580

aucaaaaggu ugucuucuau ggaaaaggca ccuacgaccc ggacggcagc auagcgggcu     2640

accaauggga cuuuggcgac gguucggacu ucucgucaga gcaaaacccu agccauguau     2700

acaccaagaa aggagaauac accguaaccc ugcgagugau ggauucaucu ggccaaaugu     2760

cugagaaaac aaugaaaaua aaaaucaccg acccaguaua ccccaucggu accgaaaaag     2820

aaccuaacaa caguaaagaa acugcaagcg gacccaucgu ccccggcauu ccugucucag     2880

gaaccaucga aaacaccagc gaucaggacu acuucuacuu ugauguaauc acccccggcg     2940

aagucaaaau cgacaucaac aaacuaggau acggcggagc cacaugggug gucuacgacg     3000

agaacaauaa cgccgucucu uacgcaaccg acgauggaca aaaccucagc gguaaauuua     3060

aagcagacaa gcccggacgc uacuacaucc accuauacau guuuaacggc uccuacaugc     3120

ccuaucgaau uaacauugag ggcucaguag gccgcugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  3344
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt8)

<400>  3344
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

gaaaaugccu auccaaacgc cucaugcuug caauaacaau ggccacaaua uuuaccguca      120

acuccacccu accaaucuac gccgccguag auaaaaacaa cgcaacagca gccguccaaa      180

acgagagcaa acgauacacc guaucauacc ucaagacccu aaacuauuac gaucuagugg      240

accuccucgu aaagacggag aucgaaaacu uaccggaucu auuucaauac uccuccgacg      300

caaaagaguu cuacgguaac aagacacgaa uguccuucau cauggacgaa aucggacggc      360

gcgcacccca auacaccgaa aucgaccaca aaggcauacc cacccuuguc gaaguuguac      420

gagccggcuu cuacuuagga uuccacaaca aggaacucaa cgaaaucaac aaacgcuccu      480

ucaaagaacg agucaucccc uccauccucg cuauucagaa gaacccaaac uucaagcucg      540

ggaccgaggu acaagauaag auagucagcg ccaccggccu gcuggccggc aaugagaccg      600

cgcccccaga gguaguaaac aauuucaccc caauccuaca agauugcauc aagaauaucg      660

accgcuacgc ccuggacgac cuaaaaucca aggcccucuu caacgugcug gccgcgccca      720

ccuacgauau caccgaauac cucagagcua ccaaagagaa acccgagaac acucccuggu      780

auggcaagau agacggcuuu auaaacgaac ucaaaaagcu agcacuguac ggcaagauca      840

augauaacaa uucauggauc aucgacaacg ggauauacca cauugccccg uuagguaaac      900

ugcacagcaa caauaaaaua ggaaucgaga cccuaacuga ggucaugaaa guauaucccu      960

aucuuagcau gcaacaccua caauccgcgg accaaaucaa gcgccacuac gacagcaaag     1020

acgcugaggg gaacaaaauc ccccuggaca aguucaagaa agagggcaag gagaaauacu     1080

gcccaaaaac cuacaccuuc gacgacggca aagucauaau caaagccggc gcgagaguag     1140

aggaagaaaa aguaaagcgg cucuacuggg ccagcaaaga agucaacagu caauucuucc     1200

gcgucuacgg caucgauaaa ccacuagaag agggaaaucc cgacgacaua cuaacaaugg     1260

uaauauacaa cagcccagag gaguacaaac ugaacuccgu ccuuuacgga uacgauacaa     1320

acaacggggg aauguauaua gaaccggaag gcacauuuuu caccuacgaa cgcgaggccc     1380

aggaaucaac auauacacuc gaggaguuau uccgccacga auacacccac uaccuacagg     1440

gacgcuacgc aguaccaggg caguggggcc gcacaaagcu cuacgauaac gaccgccuaa     1500

cgugguacga agaagggggc gccgaacucu ucgccggauc cacccgcacc agcgggaucc     1560

uaccgcgaaa gaguauagug agcaacaucc auaacaccac gcgcaacaac cgcuacaagc     1620

ucucagacac aguccacagc aaguacggag caucguucga guucuacaac uacgcaugua     1680

uguucaugga cuacauguac aacaaagaca ugggcauccu caacaaacuc aacgaucucg     1740

cgaaaaauaa cgacgucgac ggauacgaca acuauauccg cgaccucuca uccaacuacg     1800

cacucaacga caaauaccaa gaccacaugc aggaacgaau agacaacuac gaaaauuuaa     1860

ccguaccauu cguagccgac gacuaccuag uacgacacgc cuacaaaaac ccuaacgaaa     1920

ucuacuccga gaucuccgaa guugccaaac ucaaagaugc caaaucagaa gucaagaaau     1980

cccaguacuu cagcacauuc acucugagag gcagcuacac gggcggcgcg uccaaaggaa     2040

aacuagaaga ucagaaagcc augaacaaau ucaucgacga cucucuaaag aaacucgaca     2100

cauacucgug gagcgguuac aaaacacuga cugccuacuu uaccaacuac aaagucgaca     2160

guucaaaucg agucaccuac gacgugguau uucacgguua ccuacccaac gaaggggacu     2220

ccaaaaacuc acuaccuuac ggaaaaauaa augggaccua caaaggcaca gaaaaagaga     2280

aaaucaaauu cuccuccgaa ggcagcuucg acccugacgg aaagaucgug agcuaugaau     2340

gggacuucgg cgacggcaac aaaucaaacg aagaaaaccc cgagcauuca uaugacaagg     2400

uaggaaccua cacagucaag cugaaaguaa ccgacgacaa aggggaauca agcguaagca     2460

cuaccaccgc cgagaucaag gacuuaagcg aaaacaaacu gccaguaauu uauaugcacg     2520

ucccaaaauc aggcgcccua aaccagaagg ugguauuuua cgguaaaggg acguacgauc     2580

ccgacggcag caucgccggc uaucaguggg acuucgguga cggcagcgac uucucaagcg     2640

aacaaaaccc cagccacguu uacacgaaaa agggcgaaua cacagugaca cuuagaguca     2700

uggauagcuc gggucaaaug agugagaaaa cgaugaaaau aaagaucacc gaccccgugu     2760

accccaucgg caccgaaaag gaaccgaaca acucaaaaga aaccgccucc gggcccaucg     2820

uacccgggau cccuguaucu ggcacaauag aaaacacaag cgaccaagac uacuucuacu     2880

ucgacgucau aacccccggc gaagucaaaa ucgauaucaa caaacucgga uacggcggag     2940

cgacaugggu aguguacgac gaaaacaaca acgcaguauc cuacgccaca gacgacggcc     3000

aaaaccucuc cggcaaauuc aaggccgaca agcccggacg auacuacaua caccucuaca     3060

uguucaacgg aucauacaug cccuaccgga uaaacaucga aggaucggug ggacgguaag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  3345
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt8)

<400>  3345
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

gggucacauu uaucagccuc cuuuuccuuu ucagcucggc cuacagcguc caaaacgaaa      120

guaaaagaua uaccguaucc uaucucaaaa cuuuaaacua uuacgaccua guagaccucc      180

ugguaaagac ugaaauagaa aaccugccag accuauucca auacagcucc gacgcuaagg      240

aguucuacgg gaacaaaacc cgcauguccu ucaucaugga cgaaaucggg cgacgcgcac      300

cacaguacac cgaaauagac cacaaaggga uucccacucu agucgaggug guacgagccg      360

gauuuuaccu uggauuccac aacaaagaac ucaacgaaau aaauaagcga ucauucaaag      420

agcggguuau cccaagcaua cuggcaaucc aaaagaaucc aaacuucaaa cuuggcacag      480

aaguccagga caaaauaguc uccgccaccg ggcuccucgc cgggaaugaa accgcacccc      540

cagaagucgu gaauaacuuc acccccauuc uccaggacug uauaaagaac aucgaccgcu      600

acgcacucga cgaccuuaag ucaaaagcgc ucuuuaacgu ccucgcggcg ccuacauacg      660

acaucacaga auaccuucgc gcgaccaagg aaaagccaga aaacacccca ugguacggaa      720

aaauagacgg guucaucaac gaacuaaaga aacuagcgcu auacggcaaa aucaacgaca      780

acaacagcug gaucauugac aacggcauau aucacauagc accccuggga aaacuccaca      840

gcaauaacaa gaucggcauc gaaacccuaa ccgaaguaau gaaagucuac ccguaccucu      900

ccaugcagca ucuccagagc gccgaccaga uaaaacgaca cuacgacuca aaagacgcag      960

aagguaauaa gaucccacug gacaaguuca aaaaggaggg caaagaaaaa uacugcccua     1020

aaacauacac cuucgacgac ggaaagguaa uaauuaaagc cggagcacga guagaagaag     1080

aaaaaguaaa acgccucuac ugggccucaa aggaaguuaa uucacaguuc uuccgagugu     1140

acgguauaga caaaccacug gaggagggaa acccagauga cauacugacg augguaauau     1200

acaacucccc ggaagaauac aaacuaaauu caguacugua cggauacgac accaacaaug     1260

ggggaaugua caucgaacca gaaggcaccu ucuucaccua cgagcgcgaa gcccaggagu     1320

cgacauauac ccuagaagaa cuguuucgcc acgaguacac gcacuacuua caagggcgcu     1380

acgccguccc cgggcagugg ggccgaacca aacuguacga caacgaccgc cucaccuggu     1440

acgaagaagg gggagcagaa cucuucgcag gaucgacccg caccagcgga auacuccccc     1500

gcaagaguau agucagcaac auccacaaca ccaccaggaa caacagauac aaacuuucag     1560

acaccguuca cagcaaguac ggggccuccu ucgaguuuua caacuacgca ugcauguuca     1620

uggauuauau guacaacaaa gacaugggaa uacuaaacaa acucaaugac cucgccaaaa     1680

acaacgacgu cgacggcuac gacaacuaca uccgagaccu cagcagcaac uacgcccuaa     1740

acgacaaaua ucaagaccac augcaggaga ggauagauaa cuacgaaaau cucaccgugc     1800

cauucguagc cgacgacuac cucguacguc acgccuacaa aaaccccaac gaaaucuaca     1860

gcgagaucuc ggaaguagca aaacuaaaag augcuaaauc agaggugaag aaaucccaau     1920

acuucucgac cuucacucuc cgcggcuccu acacaggagg agccagcaaa gguaaacuag     1980

aggaccaaaa agcaaugaac aaauucaucg acgacucccu caagaaacuc gauaccuaca     2040

gcuggagcgg auacaaaacg uuaaccgcau auuucaccaa uuacaaagug gacaguucca     2100

accgaguaac cuacgaugua guguuccaug gcuaccuacc caacgagggc gacagcaaaa     2160

acucacuccc cuacggaaag aucaacggga cauacaaggg cacggaaaaa gagaaaauca     2220

aauucagcuc agaaggcucc uucgaccccg acggcaagau ugucuccuac gagugggacu     2280

ucggggacgg caacaaaucg aacgaggaga acccagaaca cagcuacgac aaggucggca     2340

cguacaccgu caagcucaaa guaacagacg acaaggggga auccagcgua agcacgacaa     2400

cagcagaaau caaggaccua uccgaaaaua aacuaccggu gauauacaug caugucccua     2460

aauccggcgc ucugaaucag aaggugguau ucuacgggaa gggcacguac gaccccgacg     2520

gauccauagc aggcuaccaa ugggacuucg gcgaugguuc ggacuuuucg uccgagcaga     2580

acccaagcca cguauacaca aagaaagggg aguauaccgu cacacuucga gucauggaca     2640

gcaguggcca gaugagugag aaaacaauga aaaucaaaau cacagauccc guuuacccga     2700

ucggcacaga aaaagaacca aacaauucca aagagacggc gucaggccca aucgugcccg     2760

gaauccccgu uucgggaacc auagagaaca caagcgacca agacuacuuc uacuucgacg     2820

ucaucacccc aggcgaggua aaaauagaca uaaacaaacu aggauacgga ggcgcaacau     2880

gggugguaua cgacgaaaac aacaacgcgg ucagcuaugc aacggacgac ggccaaaacc     2940

uaucaggaaa guucaaggcc gacaagcccg gaagguacua uauacauuug uacauguuca     3000

acggcagcua caugcccuac agaaucaaca ucgaaggcag cgucggccgc ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3346
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt8)

<400>  3346
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

gggugaccuu cauaucacuc cuuuuccuau ucucaucagc auacucgaug aaacgcaaau      120

gccucagcaa acgacucaug cuagcuauca ccauggccac aauauucacc guaaacucca      180

cccuacccau cuacgcggca guggacaaaa acaacgccac cgccgcacgu cgccgccgga      240

aacgcgucca aaacgaaagu aagcgcuaua cggugagcua ccucaaaacu cucaacuacu      300

augaucuagu agaccuccua gucaaaacgg aaauugaaaa ccuccccgac cuauuccagu      360

acucaucaga cgcgaaagag uucuacggca acaaaacccg gauguccuuc auaauggacg      420

aaaucggaag gcgagcaccc caguauaccg agaucgacca caagggcauc cccacgcucg      480

uagaaguagu uagagcaggc uucuaccucg gguuccacaa caaagaacua aaugagauca      540

acaaacgcuc cuucaaagaa cgcgucaucc ccucaauacu agcaauccag aaaaacccca      600

auuucaaacu aggcaccgag guacaagaua aaaucguguc cgcaacaggc cuccuggcag      660

guaaugaaac cgcgccgcca gaaguaguca acaacuucac acccauccuu caggacugca      720

ucaaaaacau agacagauac gcacucgacg accucaaaag caaagcacua uucaacgucc      780

ucgcagcacc cacauaugac auaacggaau accuuagagc aaccaaagaa aaacccgaaa      840

acacacccug guaugggaaa auagacggcu ucaucaacga gcuuaaaaag cuggcacuuu      900

acgggaaaau aaacgacaac aacagcugga ucauagacaa cggcauuuac cacaucgcac      960

cccuggggaa auugcacagc aacaacaaaa ucggcauaga aacccucacg gaggucauga     1020

aaguuuaccc auaccuguca augcaacacc uccaauccgc cgaccagauc aaacgacacu     1080

acgacagcaa agacgccgaa ggcaacaaga uaccacuaga caaguucaag aaagaaggca     1140

aagaaaaaua uugcccuaaa accuacacau ucgacgacgg aaaaguaauc auuaaagccg     1200

gcgcccgugu agaagaagaa aaggucaaac gccuauacug ggccagcaaa gaaguaaaua     1260

gccaauucuu ccgcguauac gggauagaca aaccgcuaga agaaggaaac cccgacgaca     1320

uacugaccau gguaauauau aacucaccgg aagaauacaa acucaacagc guacuauacg     1380

gcuaugacac caauaacgga ggaauguaca ucgagccaga aggaacauuc uucacguacg     1440

aacgugaagc acaagaaucc acauacaccc ucgaggaacu cuuccgucac gaguacaccc     1500

acuaccuaca ggggcgauac gccguacccg gccaaugggg ccgcaccaaa cuguaugaca     1560

acgaccggcu caccugguac gaagaagggg gcgccgaacu cuucgccggu ucgaccagga     1620

cuucaggaau acugccccgc aagagcaucg uaagcaacau ccacaauaca acccgcaaca     1680

accgcuacaa acuaucagac acaguccacu ccaaauacgg agcgucauuu gaguucuaca     1740

acuacgcuug cauguuuaug gauuauaugu acaacaaaga uauggggauc cugaauaaac     1800

uaaacgaccu agcgaaaaac aacgacguug acggcuacga caacuacaua cgugaccucu     1860

caucaaacua cgcccuaaac gacaaauacc aggaccacau gcaagaacgc aucgacaauu     1920

acgaaaaccu aacagugccu uuugucgccg acgacuaccu cguacggcac gcuuacaaaa     1980

accccaacga aaucuauuca gaaaucucag aagucgccaa auuaaaagac gcuaaauccg     2040

aagucaagaa gucccaauac uucuccacau uuacccucag aggcucauac accggaggcg     2100

cauccaaagg caaacuggag gaccaaaaag ccaugaacaa auucaucgau gacagucuaa     2160

agaaacucga caccuacucc ugguccggau acaaaacgcu aacagccuac uucacaaacu     2220

acaaaguaga cagcuccaac cgagucaccu acgacgucgu cuuccauggu uaccucccca     2280

acgaagguga cagcaaaaau ucacuccccu acggcaaaau aaacggcacc uacaaaggca     2340

ccgaaaagga gaaaaucaaa uucucaucgg aaggcagcuu cgacccagac gggaagauag     2400

uaucguauga augggacuuc ggggacggca acaaauccaa ugaagagaac cccgaacauu     2460

ccuaugacaa aguggggacc uacacaguua agcuaaaagu aaccgacgac aaaggcgaau     2520

cauccguauc aaccacaacg gccgagauaa aagaucuaag cgaaaacaaa cuccccguaa     2580

uauacaugca cgucccuaaa ucgggagcuc ucaaccaaaa agucguauuc uacggaaaag     2640

gaacauacga cccugacggc uccauagccg gcuaccaaug ggacuuuggc gacggcagcg     2700

acuucuccag ugagcaaaac cccucacacg ucuacacgaa aaagggcgaa uacaccguga     2760

cacuucgcgu aauggacagc agcggccaga uguccgagaa aaccaugaaa aucaagauua     2820

ccgacccagu cuaccccaua ggcaccgaaa aggaaccgaa caauagcaag gaaacagcca     2880

gcggcccaau agucccgggg auccccgucu ccggcacgau cgaaaacacu uccgaccagg     2940

acuacuucua cuucgacgua auaacccccg gcgaaguaaa aaucgacauc aacaaacuag     3000

gauacggagg cgccaccugg gucgucuacg augaaaacaa caacgccgua uccuaugcca     3060

cagacgaugg ccagaacuug ucaggcaagu ucaaagcuga caagcccgga cgcuacuaca     3120

uccaccugua cauguucaau ggcuccuaca ugccauaccg aauaaacauc gaaggaucgg     3180

ucggacgcug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  3347
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt8)

<400>  3347
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu auucgcaugc cuccucggag ccgccuucgc caugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucucuu acgaaguccu caccccccua aaaugguacc      180

aaucaauucg cccccccuau ccauccuacg gcuacgaacc caugggcggc uggcuacacc      240

accaaauaau acccguccuc ucccaacaac acccccccac ccacacccuc caaccccacc      300

accacauccc cgucgucccc gcacaacaac ccgucauccc ccaacaacca augaugccag      360

ucccaggcca acacucuaug acccccaucc aacaccacca acccaaccuc cccccccccg      420

cacaacaacc auaccaaccc caacccgucc aaccacaacc ccaccaaccc augcaacccc      480

aaccccccgu ccaccccaug caaccccucc caccccaacc accccucccc cccauguucc      540

ccaugcaacc ccuccccccc augcuacccg accuaacccu cgaagccugg cccuccacag      600

acaaaacaaa acgagaagaa gucgacuaag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  3348
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt8)

<400>  3348
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccacccca ccccggccac cccggauaca uaaacuucuc cuacgaaguc cuaacacccc      120

uaaaauggua ccaauccaua cgcccacccu accccuccua cggcuacgaa cccaugggcg      180

gaugguaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  3349
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt8)

<400>  3349
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccacccca ccccggccac cccggcuaca uaaacuucuc cuacgaaguc cucacaccac      120

ucaaauggua ccaauccauc cgcccaccac ccaugcuccc cgaccucacc cucgaagccu      180

ggcccuccac cgacaaaaca aaacgcgaag aagucgacua aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  3350
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt8)

<400>  3350
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcacc ccgaacccua guccuacucc uauccggcgc ccuagcccuc acccaaaccu      120

gggccaugcc acuaccaccc cacccaggcc accccggcua caucaacuuc uccuacgaag      180

uacucacacc acuaaaaugg uaccaaucca uccgaccacc cuaccccucc uacggcuacg      240

aacccauggg cggcugguaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  3351
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt8)

<400>  3351
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

uaauggcacc ccgaacacuc guacuccucc ucuccggagc acuagcccuc acccaaaccu      120

gggccaugcc ccucccccca caccccggcc accccggcua cauaaauuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaucca uccgcccccc ccccaugcuc cccgaccuaa      240

cacucgaagc cuggcccuca accgacaaaa caaaacgcga agaagucgac uaaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  3352
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt8)

<400>  3352
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu auucgcaugc cuagucggcg ccgccuucgc caugccccuc ccaccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgaaguacu caccccacuc aaaugguacc      180

aauccaugau acgcccaccc uacuccuccu acggauacga acccaugggc ggcuggcucc      240

accaccaaau aauccccguc guuucccaac aacacccccu cacccacacc cuccaaucac      300

accaccacau ccccguaguc cccgcccaac aaccccgagu ccgccagcaa gcccucaugc      360

ccguaccagg ccaacaauca augaccccca cccaacacca ccaacccaac cucccccucc      420

ccgcccaaca acccuuccaa ccccaacccg uccaacccca accacaccaa ccaaugcaac      480

cccaaccacc cguccaaccc augcaacccc uucuccccca accuccccua ccacccaugu      540

ucccccuccg uccucuccca cccauccucc ccgaccucca ccucgaagcc uggcccgcca      600

ccgacaaaac caaacaagaa gaaguagacu gaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  3353
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt8)

<400>  3353
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

uaccacccca ccccggccac cccggcuaca uaaacuucuc cuacgaaguc cucaccccac      120

ucaaauggua ccaaucaaug auacgaccac ccuacuccuc auacggcuac gaacccaugg      180

gcggcuggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3354
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt8)

<400>  3354
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

uccccccaca ccccggccac cccggcuaca uaaacuucuc cuacgaaguc cuaacaccac      120

ucaaauggua ccaauccaug auccgccccc cccccauacu ccccgaccuc caccucgaag      180

ccuggcccgc cacagacaaa accaaacaag aagaagucga cuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3355
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt8)

<400>  3355
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc acgcacacuc guccuccuac ucucaggagc ccucgcacuc acacaaaccu      120

gggccaugcc acucccacca caccccggcc accccggcua caucaacuuc ucauacgaag      180

uccucacccc acucaaaugg uaccaaucaa ugauacgccc acccuacucc uccuacggcu      240

acgaacccau gggcggaugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3356
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt8)

<400>  3356
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

ucauggcacc ccgcacccuc guccuacuac ucuccggcgc ccucgcccuc acccaaacau      120

gggccaugcc acucccaccc caccccggac accccggcua caucaacuuc ucauacgaag      180

uccucacccc acucaaaugg uaccaaucca ugauccgacc cccacccauc cuacccgacc      240

uccaccucga agccuggccc gccaccgaca aaaccaaaca agaagaaguc gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3357
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt8)

<400>  3357
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgcaugc cuccucggcg ccgccuucuc caugccucua ccaccccacc      120

ccggccaccc cggcuacauu aacuucuccu acgaaguccu aacuccccua aaaugguacc      180

aaaacaugau ccgacacccc uacaccuccu acggauacga acccaugggc ggauggcucc      240

accaccaaau cauccccguc gucucccaac aaacacccca aucccacgcc cuacaacccc      300

accaccacau ccccauggua cccgcccaac aacccgguau accccaacaa cccaugaugc      360

cccuccccgg ccaacacuca augaccccca cccaacacca ccaacccaac cuaccccuac      420

ccgcacaaca acccuuccaa ccccaaccag uccaacccca accccaccaa ccacuccaac      480

cccaaucccc caugcacccc auccaacccc uccucccaca accaccccuc ccacccaugu      540

ucuccaugca aucacuccuc cccgaccucc cccucgaagc cuggcccgca accgacaaaa      600

ccaaacgcga agaagucgac uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3358
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt8)

<400>  3358
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

uaccacccca cccaggccac cccggcuaca ucaacuucuc cuacgaaguc cucacaccac      120

ucaaauggua ccaaaacaug aucagacacc cauacaccuc auacggcuac gaacccaugg      180

gcggcuggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3359
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt8)

<400>  3359
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uacccccaca ccccggccac cccggcuaca uaaacuucuc auacgaagua cucaccccac      120

ucaaauggua ccaaaacaug auccgacacc ccucccuccu ccccgaccuc ccccucgaag      180

ccuggcccgc caccgacaaa accaaacgcg aagaagucga cuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3360
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt8)

<400>  3360
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

ucauggcacc ccgcacacuc guccuccuac uaucaggagc ccucgcacuc acacaaacau      120

gggccaugcc ccuaccaccc caccccggac accccggcua cauaaacuuc uccuacgaag      180

uccuaacacc ccuaaaaugg uaccaaaaca ugauccgaca ccccuacacc uccuacggcu      240

acgaacccau gggcggcugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3361
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt8)

<400>  3361
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc acgcacccua guccuccucc uauccggcgc acucgcacuc acacaaaccu      120

gggccaugcc ccucccacca caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacacc ccucaaaugg uaccaaaaca ugauccgcca cccaucacuc cucccagacc      240

ucccacucga agccuggccc gccaccgaca aaaccaaacg cgaagaagua gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3362
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt8)

<400>  3362
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauacu cuucgcaugc cuccucggcg ccgccuucuc caugccccuc ccaccccacc      120

ccggccaccc cggcuacauc aacuucuccu acauccgcca cccauacacc uccuacggcu      180

acgaacccau gggcggcugg cuacaccacc aaaucauccc cgucgucucc caacaaacac      240

cccaauccca cgcccuacaa ccccaccacc acaucccaau gguccccgcc caacaaccag      300

gcaucccaca acaacccaug augccccuac ccggccaaca cucaaugacc ccaacucaac      360

accaccaacc caaccuaccc cuacccgccc aacaacccuu ccaaccccaa cccguccaac      420

cccaacccca ccaaccccuc caaccccaau cccccaugca ccccauccaa ccccuccuac      480

cccaaccacc ccucccaccc auguucucaa ugcaaucccu acuccccgac cuaccccucg      540

aagcauggcc cgcuacagac aaaacaaaac gcgaagaagu cgacuaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  3363
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt8)

<400>  3363
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

ccuggaucuu cuucgccugc cuccucggcg ccucccucgc aaugccccuc ccaccccacc      120

ccggccaccc cggcuacauc aacuucuccu augaaguacu cacaccccuc aaaugguauc      180

aaaacaugau ccgccacccc uacacauccu acggcuacga acccaugggc ggcuggcuac      240

accaccaaau cauacccguc gucucacaac aaacacccca aucacacgcc cuccaacccc      300

accaccacau ccccaugguc cccgcccaac aacccggcau cccccaacaa cccaugaugc      360

cccuaccagg acaacacucc augaccccaa cccaacauca ccaaccuaau cucccccucc      420

ccgcccaaca acccuuccaa ccccaacccg uccaacccca accccaccaa ccccuccaac      480

cccaaucccc caugcacccu auccaacccc uccuccccca accaccccuc ccacccaugu      540

ucuccaugca aucacuccua cccgaccucc cccucgaagc cuggccugcc accgacaaaa      600

caaaacgcga agaagucgac uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3364
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt8)

<400>  3364
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauacu cuucgccugc cuccucggcg ccgcauucuc aaugccccuc ccaccacacc      120

caggccaccc cggauacauc aacuucuccu acgaaguacu caccccacuc aaaugguacc      180

aaaacaugau ccgacacccc ucacuccucc ccgaccuccc ccuagaagcc uggccagcca      240

ccgacaaaac caaacgcgaa gaagucgacu aaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  3365
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt8)

<400>  3365
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cuccuaggcg cugccuucuc caugccacuc ccaccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgaagaccu auaccucgaa gccauacgca      180

ucgaccgcac cgcauuuguc cuaaccccac ucaaauggua ccaaaacaug auccgacacc      240

cauacaccuc cuacggcuau gaacccaugg gaggcuggcu acaccaccaa aucaucccag      300

ucgucucaca acaaaccccu caaucucacg cccuccaacc acaccaccac auccccaugg      360

uccccgccca acaacccggc aucccccaac aacccaugau gccccucccc ggccaacacu      420

ccaugacccc cacccaacac caccaaccca accucccccu ccccgcacaa caacccuucc      480

aaccccaacc aguccaaccc caaccacacc aaccccuuca accccaaucc cccaugcacc      540

ccauccaacc ccuccuacca caaccacccu uaccucccau guuuucuaug caaucccucc      600

uccccgaccu cccccucgaa gccuggcccg ccaccgacaa aacaaaacgc gaagaaguag      660

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  3366
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt8)

<400>  3366
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

ccuggauccu auucgccugc cuccuaggag ccgccuucuc aaugccccua ccaccccacc      120

ccggccaccc cggcuacauc aacuuuuccu acgaaguccu caccccacuc aaaugguacc      180

aaaacaugau acgccacccc acaccccaau cccacgcccu acaaccccac caccacaucc      240

ccaugguccc cgcccaacaa cccggcaucc cccaacaacc caugaugccc cuccccggcc      300

aacacuccau gacccccacc caacaccacc aacccaaccu cccccucccc gcccaacaac      360

ccuuucaacc ccaacccguc caaccccaac cacaccaacc acuccaaccc caauccccca      420

ugcacccaau ccaaccccuc cucccccaac caccccuccc acccauguuc ucaaugcaau      480

cacuacuccc cgaccucccc cucgaagccu ggcccgccac cgacaaaacc aaaagagaag      540

aagucgacua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  3367
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt8)

<400>  3367
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

ucccacccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc cucacacccc      120

ucaaauggua ccaaaacaug auccgccacc ccuacaccuc auacggcuac gaacccaugg      180

gcggcuggcu ccaccaccaa aucauccccg ucgucuccca acaaacaccc caaucacacg      240

cacuccaacc ccaccaccac auccccaugg uccccgccca acaacccggc aucccccaac      300

aacccaugau gccacucccc ggccaacacu caaugacccc cacccaacac caccaaccca      360

accucccacu ccccgcacaa caacccuucc aaccacaacc cguacaaccc caaccccacc      420

aaccacucca accccaaucc cccaugcacc ccauccaacc ccuacucccc caaccacccc      480

uacccccaau guucucaaug caaucccucc uccccgaccu cccccucgaa gcauggccag      540

ccacagacaa aaccaaacgc gaagaagucg acuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  3368
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt8)

<400>  3368
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

gcguugcaag acuaccacua cucuuaggac uacuacuacu accgcgacca ggacgacccc      120

ucgaccuagc agacuacacc uaugaccucg ccgaagaaga ugauagcgaa ccgcuaaauu      180

acaaagaccc guguaaagca gcagcuuuuc uaggcgacau agcccuggac gaggaagacc      240

uucgggcguu ccaaguacaa caggcaguag auuuacgccg acacacggcu cgaaaaucau      300

caaucaaagc agccguucca ggaaacacgu caaccccaag cugucaguca acaaaugggc      360

aaccccaacg cggagcgugc ggacgauggc gaggccgcag caggucccgc agagcagcca      420

ccucccgccc cgaaagaguc uggcccgaug gaguaauacc guucguaaua ggcggcaauu      480

ucaccggauc ccagcgcgcg gucuuccgcc aagccaugag acacugggag aaacauaccu      540

gcgugacauu ccucgaaaga acagacgaag acucauacau aguauucacc uaccgaccgu      600

gcggcugcug cagcuacgua ggccgcagag gcggcgggcc acaagcgauc agcaucggca      660

aaaacugcga caaauucgga auagucgucc acgaacucgg ccacguagua ggcuucuggc      720

acgagcacac ccgaccugac cgagaccgac acgucagcau cguaagagaa aacauacaac      780

cagggcaaga auacaacuuc cugaaaaugg agccccaaga aguggaaucc uuaggagaaa      840

ccuacgacuu ugacucaauc augcacuacg caaggaacac auucucacga ggaauauucc      900

ucgacacaau aguucccaag uacgaaguga acgggguuaa accuccgauu ggccaaagga      960

caagacuauc aaagggcgac aucgcacagg cacgaaaacu guacaaaugc cccgcaugcg     1020

gggagacacu acaagacagc accgggaacu ucucaagucc ggaauaccca aacggauaca     1080

gugcucacau gcacugcgua uggcggauaa gcgucacccc gggcgagaaa auaauacuaa     1140

acuucacaag ucuggaccua uaccggagcc gccuuugcug guacgauuac guagaagucc     1200

gcgacggauu cuggcgcaaa gcgccacuga ggggacgcuu cugcggauca aaacucccgg     1260

aaccgauagu aucaaccgac ucacgccucu gggucgaguu cagaagcagc ucaaacuggg     1320

ucggaaaagg auucuuugca guguacgaag cuaucugcgg aggagacgua aagaaagacu     1380

augggcacau acaaagcccc aacuaccccg acgacuaccg cccuagcaaa guuugcaucu     1440

ggcgcauaca agucagcgaa ggcuuccacg ucggccugac auuccagagu uucgaaauag     1500

aacgccauga cagcugcgcc uacgauuacc ucgaaguccg cgacggccac ucggaaagca     1560

gcaccuuaau cggcagguac ugcgguuacg aaaaaccaga cgacauaaag agcaccucga     1620

gccgacucug gcuaaaauuc guaagcgacg gcagcauaaa caaagcgggc uuugcaguua     1680

acuucuucaa agaaguggac gaaugcucca ggccaaaccg aggcgggugc gaacaaagau     1740

gucuaaauac acucggcagc uacaaaugca gcugcgaccc gggauacgaa cucgcccccg     1800

acaaaagaag gugcgaagcc gccugcggag gguuccucac aaaacuaaac gggagcauca     1860

cuucaccggg auggccaaaa gaauacccac caaauaagaa cugcaucugg caacucgucg     1920

cacccaccca auaccgcauc agccuacaau ucgacuucuu cgaaaccgaa ggcaacgacg     1980

ucugcaaaua cgacuucguu gaaguccgcu ccggacuaac agcagacagc aaacuacacg     2040

guaaauucug cggcuccgaa aagccagaag ucauaacaag ccaauacaac aauaugagag     2100

ucgaguucaa gagcgacaac accgucagca aaaagggauu uaaggcacac uucuucucag     2160

acaaagacga augcucaaaa gacaacggcg gcugccaaca agacugcguu aacacauucg     2220

gcucauacga augccaaugc agaucagguu ucgugcugca cgacaacaaa cacgacugca     2280

aagaagccgg cugcgaccau aaaguuacca gcaccagugg aaccauaaca agccccaacu     2340

ggccagacaa auacccaucg aagaaagaau gcacgugggc uaucuccagc acacccgggc     2400

accgggucaa acucaccuuc auggaaaugg auaucgaaag ccaaccggaa ugcgcauacg     2460

accaucuaga agucuuugac ggccgagacg ccaaagcccc aguacucggc agauucugcg     2520

gauccaagaa accagaacca guacucgcga ccgggagccg aauguuccuc cgcuucuaca     2580

gcgacaacuc cgugcaacgc aaaggcuucc aagccuccca ugcgacggaa ugcggcggac     2640

aaguucgcgc ggacgucaaa accaaagacu uauacagcca ugcacaguuc ggugacaaca     2700

auuaccccgg aggcguagac ugcgaauggg ucauaguagc cgaagaagga uacggcgucg     2760

agcucguauu ccagacauuc gaaguagaag aagaaaccga cugcggcuac gauuacaugg     2820

aacuuuucga cggguacgac agcacagcgc cacgccucgg acgcuacugc ggaucaggcc     2880

cgccagaaga aguauacagc gcaggcgacu ccguccuagu caaauuccau ucugaugaca     2940

ccaucacaaa gaaaggcuuc cacuugagau acacaaguac aaaauuccaa gacaccuuac     3000

auucaagaaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  3369
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt8)

<400>  3369
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucg       60

ccggaacucg cugccuccua gcccuccuac ucccccaagu acuacucggc ggcgccgccg      120

gccucguucc cgaacucgga cgacgaaaau ucgccgccgc auccucugga aggcccagcu      180

cccaacccuc cgacgaaguu cucuccgagu ucgaacuccg ccuccucuca auguucggcc      240

ucaaacaacg ccccacacca ucacgcgacg cagucguccc gcccuacaug cucgaccuau      300

accgucguca cucaggccaa cccggauccc ccgcccccga ccaccgucuc gaacgcgcag      360

ccucgcgcgc caacacaguc cgcuccuucc accacgaaga aucccucgaa gaacuacccg      420

aaaccuccgg caaaacaacc cgacgcuucu ucuucaaccu cagcuccauc cccacagaag      480

aguucauaac cuccgccgaa cuacaaguau uccgcgaaca gaugcaagac gcccucggaa      540

acaacagcuc auuccaccac agaaucaaca uuuacgaaau aaucaaaccc gccaccgcga      600

acagcaaauu ucccgucacc cgucuccucg acacccgccu cgucaaccaa aacgccuccc      660

gcugggaauc uuuugacgua acacccgcag ucaugcgcug gacagcacaa ggccacgcca      720

accacggauu cgucguagaa guagcccacc uagaagaaaa gcaaggagua uccaaacguc      780

acguacgaau aucacgcucc cuacaccaag acgaacacuc cuggucccaa auccgacccc      840

uacucgucac cuucggccac gacggaaaag gacacccccu ucacaaaagg gaaaaacgcc      900

aagccaaaca caaacaacgc aaacgacuca aauccucaug caaaagacac ccccucuacg      960

uugauuucuc agacgucggc uggaacgacu ggaucguagc cccacccggc uaccacgccu     1020

ucuacugcca cggcgaaugc cccuuccccc ucgcagacca ccuuaauuca accaaccacg     1080

caaucgucca aacccucguc aacuccguca acucaaaaau ccccaaagcc ugcugcgucc     1140

ccaccgaacu aucagccauc uccauguuau accuagacga aaacgaaaaa gugguccuca     1200

aaaacuacca agacaugguc gucgaagguu gcggcugccg auaaggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  3370
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt8)

<400>  3370
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauac       60

ccggcaaccg caugcucaug gucguccucc ucugccaagu acuccucgga ggagccucac      120

acgccucacu cauaccagaa acuggcaaaa aaaaagucgc ugaaauccaa gggcacgccg      180

gcggccgccg cuccggccaa ucccacgaac uucuuagaga cuucgaagcc acccuacucc      240

aaauguucgg acuccgccgc cgcccccaac ccuccaaauc ugcaguuaua cccgacuaca      300

ugcgcgaccu auaccgucua caaucaggcg aagaagaaga agaacaaauc cauaguaccg      360

gccucgaaua ccccgaacgc cccgccuccc gcgcaaauac aguccgcuca uuccaucacg      420

aagaacaccu cgagaacauc cccggaacgu ccgaaaacuc cgccuuccga uuccucuuca      480

accuaucauc cauccccgaa aacgaaguca ucuccuccgc cgaacuccgc cuuuuccgcg      540

aacaagucga ccaaggcccc gacugggaac gcggcuucca ccgcauaaac aucuacgaag      600

uaaugaaacc acccgccgag gucguccccg gacaccuuau cacacgccuc cucgacaccc      660

gacuagucca ccacaacguc acccgauggg aaaccuucga cguauccccc gcaguccucc      720

gcuggacccg cgaaaaacaa cccaacuacg gacucgccau agaaguuaca caccuccacc      780

aaacccgaac acaccaaggc caacacgucc gaaucucccg cucccuccca caaggcuccg      840

gcaacugggc ccaacuccgc ccccuccucg uaaccuucgg acacgacgga cgcggacacg      900

cccucacccg acgccgccga gccaaacgcu cccccaaaca ccacucacaa agagccagga      960

aaaaaaauaa aaauugccgc cgccacucac ucuacguaga cuucagcgac gucggcugga     1020

acgacuggau agucgccccc cccggcuacc aagcauucua cugccauggc gacugccccu     1080

ucccacucgc cgaucaccua aacagcacca accacgccau aguccaaacc cuaguaaacu     1140

ccgucaacuc cagcauaccc aaggcaugcu gcguacccac agaacugagc gcaaucucca     1200

uguuauaccu cgacgaauac gacaaaguag uacucaaaaa cuaccaagaa augguaguag     1260

aaggaugcgg cugccgcuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  3371
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt8)

<400>  3371
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gauuaggucg ccgagcacag uggcucugcu gguggugggg acuccucugu agcugcugcg      120

gacccccccc ccuacgccca ccucuccccg ccgcugccgc cgccgccgcc ggcggccaac      180

uacucggaga cggcggauca cccggccgaa cugaacaacc accccccuca ccccaauccu      240

caagcggguu ccucuaccgu cgccugaaaa cccaagaaaa acgcgaaaug caaaaagaaa      300

uccuauccgu ccucggccuc ccccaccgcc cccgcccccu acacggacug caacaacccc      360

agccaccagc ccuacgucaa caagaagaac agcagcaaca acaacaauua ccaagaggag      420

aaccaccccc uggccgacug aaauccgccc cacuauucau gcucgaccua uacaacgcac      480

ucagcgcaga caaugacgaa gacggcgcau cagaaggaga aagacaacaa ucauggccac      540

acgaagcagc cucaagcucc caacgaagac aaccaccacc cggagcagcg cacccccuaa      600

accgcaaauc ccuacuggcc cccggauccg gcagcggcgg cgccucccca cuaaccagcg      660

cccaagacuc ugcauuccuu aacgacgcag acauggucau gucauucguu aaccuggucg      720

aauacgacaa agaauucucg ccccgacaac gacaucacaa ggaauucaaa uucaaccuca      780

gccagauacc cgaaggcgaa guagucaccg ccgccgaguu ccgcaucuau aaagacugcg      840

ucaugggauc auucaaaaac caaacauucc uaaucuccau cuaccaagua cuccaagaac      900

accagcaccg cgacagcgac cucuuccuau uagacacccg cguagucugg gccucagaag      960

aaggcuggcu cgaauucgac auaacugcca ccucaaaucu uugggucguc acaccacaac     1020

acaacauggg ccuccaacuc uccguaguca cccgugacgg aguccacgua cacccccgag     1080

cugccggccu cgucggacga gacggccccu acgacaaaca acccuucaug gucgcauucu     1140

ucaaagucuc cgaaguccac guccgaacca cccgcucagc cuccucccgu cgcaggcaac     1200

aaucccgaaa ccgauccaca caaucccaag auguagccag aguauccucc gccuccgacu     1260

auaacuccuc cgaacucaaa acagcaugcc gcaaacacga acucuaugua uccuuccaag     1320

accuuggaug gcaagacugg aucaucgccc caaaaggaua cgccgccaac uacugcgacg     1380

gcgaauguuc auucccucua aacgcccaca ugaacgcaac caaccacgcc aucguacaaa     1440

cacuugucca ccucaugaau cccgaguacg uccccaaacc cugcugcgca cccaccaaac     1500

ucaacgccau aucagucuua uacuucgacg acaacucaaa cguaauccug aaaaaauacc     1560

gcaacauggu cguucgcgca ugcggcugcc acuaaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  3372
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt8)

<400>  3372
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

uccguucccu gagagccgcc gccccccacu cguuugucgc ccuaugggca ccccuauucc      120

uccuucgauc agcacuugca gacuucuccc uugacaacga aguccacucg uccuucaucc      180

accgccgccu cagaucacaa gaacgacgag aaaugcaacg cgaaauacuu agcauccuag      240

gccuccccca ccguccccga ccacaucucc aaggcaaaca caacucagcc ccaauguuca      300

ugcucgaccu cuacaacgcc auggccgucg aagagggcgg cggacccggc ggucaaggcu      360

ucuccuaccc auacaaagcc gucuucagca cucaaggacc accccucgcu ucccuucaag      420

acucccacuu ccuaaccgac gcagauaugg ucauguccuu cgucaaccua gucgagcacg      480

acaaagaauu cuuccacccc cgcuaccacc accgagaauu ccgcuucgac cucuccaaaa      540

uacccgaagg cgaggccguc acagcugccg aauuccgcau cuacaaagac uacauccgcg      600

aacgcuucga caacgaaacc uucaggaucu cagucuauca aguccuacaa gaacaucucg      660

gccgcgaauc cgacuuauuc cuccuagacu cacgcacccu cugggccuca gaagaaggau      720

ggcucguauu cgacaucaca gccacaucaa accacugggu cgucaacccc cgccacaacc      780

ucggccugca gcuaucagua gaaacccucg acggacaauc caucaacccc aaacucgccg      840

gucucaucgg ccgacacggc ccacaaaaca aacagcccuu cauggucgcc uucuucaaag      900

ccaccgaagu ccacuuccga agcauccgcu ccaccggauc caaacaacgc ucccagaauc      960

guuccaaaac cccgaaaaac caagaggccc uacgcauggc caacgucgca gaaaacuccu     1020

caucagacca acgccaagcc ugcaaaaaac acgaacuaua cgucuccuuc cgcgaccucg     1080

gauggcaaga cuggaucauc gcaccagaag gcuacgccgc cuacuacugu gaaggagaau     1140

gcgccuuucc ucucaacucc uacaugaacg ccaccaacca cgcaauugua caaacccuag     1200

uucacuucau caacccagaa acagucccaa aacccugcug ugcccccaca caacuaaacg     1260

caauauccgu ccucuacuuc gacgauuccu cgaacguuau ccucaaaaaa uaccgcaaca     1320

ugguaguccg agccugcgga ugccacugag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  3373
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt8)

<400>  3373
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaag       60

ccucagccgc ccuccucugc cuccuccuca cagcagccgc cuucuccccc caaggccucg      120

cccaaccagu cggcaucaac accuccacaa ccugcugcua ccgcuucaua aacaaaaaaa      180

uacccaaaca acgccuagaa uccuaccgca gaaccacauc cucacacugc ccccgcgaag      240

ccgucaucuu caaaaccaaa cuagacaaag aaaucugcgc cgaccccacc caaaaauggg      300

uccaagacuu caugaaacac cuagacaaaa aaacacaaac ccccaaacuc uaaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  3374
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt8)

<400>  3374
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugu       60

uaacgcuaau cauccuacua ccagucguaa gcaaguucuc uuuugucucc cugagcgcgc      120

cccagcauug guccugccca gaaggcaccc ucgcaggcaa uggaaacagc acaugcguag      180

gcccggcucc auuccuaauc uucagccaug gcaacagcau cuuuagaauc gacaccgagg      240

gcaccaacua cgaacaacuc gugguagaug ccggagugag cguaauaaug gacuuccacu      300

acaacgaaaa acgcauauau ugggucgacc uagaacggca gcuccuccaa aggguauuuc      360

ucaacggauc ccgacaggag cgggugugca auaucgagaa aaacgucucc ggaauggcaa      420

ucaacuggau caacgaagaa gucaucugga gcaaucagca ggaaggaauc auaacaguca      480

cugauaugaa gggcaauaac ucccacauac uacucucagc acuaaaauac cccgccaacg      540

uagcaguaga uccuguggaa cgcuucaucu ucuggagcuc agagguagcc gguagccucu      600

acagagcgga ucuugacgga guggguguga aagcacuuuu agaaacaagc gagaaaauaa      660

ccgcaguauc ccuugacgug cucgacaaac gacuauuuug gauucaguac aaucgggaag      720

gcucgaacuc ccuaauaugc ucgugcgauu acgacggcgg aagcguacac auaagcaagc      780

accccacgca gcacaaccuc uuugcaaugu cccuguucgg ugaccgaauc uucuacucca      840

ccuggaaaau gaagaccaua uggaucgcga acaaacauac agggaaagau auggucagaa      900

ucaaccuaca cagcuccuuc gucccccuag gagaacuaaa ggucguacau ccacucgccc      960

aacccaaagc ggaagacgac accugggaac cggaacaaaa auugugcaaa uuaagaaagg     1020

guaauugcuc cagcacuguc ugcgggcaag accuccaauc acaccucugc augugcgcgg     1080

aaggguaugc ccugagccgg gaccgcaaau auugcgaaga cgucaaugaa ugcgccuucu     1140

ggaaccacgg auguacgcuu gguugcaaaa acacacccgg gagcuacuac uguaccugcc     1200

ccguaggcuu cguccuacug ccggacggca agcgguguca ucagcuaguc aguugcccac     1260

gcaacguuuc agaaugcagc cacgacugcg uccuaacauc cgagggacca cucuguuucu     1320

gcccagaagg cucagugcua gaaagagacg gaaaaacaug cagcgggugc ucaagcccag     1380

auaauggcgg gugcucgcaa cuaugugugc cacuaucccc ugucuccugg gaaugcgacu     1440

gcuuccccgg auacgaucuc caacucgacg aaaagucaug cgccgccagu ggcccccaac     1500

ccuuucuucu auucgccaac agccaagaca uucgccacau gcacuucgac ggaacagacu     1560

acggaacccu cuuaucucaa cagaugggca ugguuuacgc cuuagaucac gacccugugg     1620

aaaacaaaau auacuucgcc cacacagcac uaaaauggau cgaaagagca aauauggacg     1680

gcucacaacg agaacgccuc auagaagagg gcguagacgu acccgaaggc cuagcgguug     1740

acuggauagg cagaagguuc uacuggacug accgaggcaa gucucugaua gggcgcucgg     1800

accugaacgg caaacgcucc aaaaucauaa caaaggagaa caucucccaa cccagaggaa     1860

ucgcaguuca cccaauggcc aaacgacugu ucuggaccga cacuggaauc aacccgcgga     1920

ucgaaucuuc cagucuacag gggcuggggc gucucguuau ugcaucgagc gaccugauau     1980

ggcccagcgg cauaacgaua gacuuccuga cagacaaacu guacuggugc gacgcaaaac     2040

aaagcgugau cgaaauggcc aaucucgacg gaucaaaaag acgcagacuc acacagaacg     2100

acgugggcca cccuuucgcu guagccguau ucgaagacua cgucugguuc ucagacuggg     2160

ccaugcccag cguaaugcga guuaacaaac gcaccgguaa agacagaguc cgucuccaag     2220

gcucaaugcu aaagccuagu ucccuuguag uaguacaucc acuagcuaaa cccggugcag     2280

acccgugccu auaccagaac gguggaugug aacacauuug caaaaagcga uugggaaccg     2340

ccuggugcag cuguagagaa ggauucauga aagcgaguga cggaaaaaca ugccucgcac     2400

ucgacggcca ccagcuccua gccggagggg aaguagaucu caaaaaccaa gugacgcccu     2460

uagacauacu aagcaaaacc agaguaucgg aggacaacau cacggagagc caacacaugc     2520

uuguagcuga aaucauggua agcgaccaag acgauugcgc gccagucgga ugcagcaugu     2580

acgcacggug caucuccgaa ggugaagaug cuaccugcca gugccuaaaa ggauuugcgg     2640

gagacggcaa acuauguagc gauaucgacg aaugcgaaau gggagucccu gucuguccgc     2700

cagcaagcuc caaaugcauc aacaccgagg gagguuacgu augccgaugc uccgagggau     2760

aucaaggaga cggcauacac ugccucgaca uagacgaaug ccaacuggga gagcacuccu     2820

gcggcgaaaa cgcaagcugu accaacacag agggcggcua cacaugcaug ugcgccggcc     2880

gccuaucuga acccggacuc aucugccccg acucgacccc uccuccgcac cuacgugagg     2940

acgaccacca uuacagcgug cgaaauuccg acucggagug cccccuaucc cacgacggau     3000

acugccuuca ugacggcguc ugcauguaua ucgaagcccu agacaaauac gcguguaauu     3060

gcguugucgg cuacaucggg gaacgaugcc aguaccgcga ccuaaaaugg ugggaacuaa     3120

ggcacgccgg gcauggccag cagcagaaag ucauagucgu ggcagucugc guaguggugc     3180

ucgucaugcu acuccuacua ucacucuggg gagcgcacua cuaccgcacc caaaaacuuc     3240

uaagcaaaaa ucccaaaaac ccauacgagg aaucaagccg ggauguucga ucgaggcgac     3300

cagcggacac agaagauggc augagcucgu gcccgcagcc cugguucgug gugaucaagg     3360

agcaucaaga ccugaaaaac gggggacaac caguagccgg ugaagacggc caagcagccg     3420

acgguagcau gcagccaacc ucauggagac aagaaccaca acucugcggu augggcacag     3480

aacagggcug cuggauuccc gucucauccg acaagggcag cugcccccaa guaauggagc     3540

gauccuucca caugccaagc uacggaacgc agacccuaga aggcggggua gaaaagccgc     3600

auucccugcu gucugccaac ccccuguggc aacagcgcgc acucgaccca ccucaccaga     3660

uggaacucac acaaugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  3375
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt8)

<400>  3375
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

ccggccgacg aauggaaaug cucugcgccg gccguguccc cgcacuucuc cucugccucg      120

gauuccaccu acuccaagcc guccucucca ccaccgucau ccccucaugc auccccggag      180

aauccuccga caacugcacc gcccuaguac aaacagaaga caacccccgc gucgcacaag      240

uuuccaucac caaaugcucc ucagacauga auggcuacug ccuccacgga caaugcauau      300

accuagucga caugucccaa aacuacugcc gcugugaagu cggauacaca ggcguccgcu      360

gcgaacacuu cuuccucacc guccaccaac cccuauccaa agaauacguc gcccucaccg      420

ucauccucau aauccuauuc cucaucacag uugucggcuc caccuacuac uucugccgcu      480

gguaccgcaa uagaaaaucc aaagaaccaa aaaaagaaua cgaacgcgua accucaggcg      540

accccgaacu cccacaaguc uaaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  3376
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt8)

<400>  3376
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

aaggcgaaau aaccacauuc accgcccuca ccgaaaaauu caaccucccc ccaggcaacu      120

acaaaaaacc aaaacuccua uacugcucca acggcggaca cuuccuccgc auccuccccg      180

acggcacagu cgacggaacc agagaccgcu cagaccaaca cauccaacuc caacucuccg      240

ccgaaucagu cggagaagua uacaucaaaa gcaccgaaac cggacaauac cuagccaugg      300

acaccgacgg cuuacucuac ggcucacaaa cccccaacga agaaugccuc uuccucgaac      360

gccucgaaga aaaccacuac aacacauaca ucuccaaaaa acacgcagaa aaaaacuggu      420

ucgucggccu caaaaaaaac ggcuccugca aacgcggccc ccgcacccac uacggccaaa      480

aagccauacu cuuccucccc cuccccgucu caucagacua aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  3377
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt8)

<400>  3377
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

ggguaggggg aggggaugug gaggauguaa cgccgaggcc agggggaugc caaauaagug      120

gaagaggggc caggggaugu aacgggaucc cgggagcggc agcgugggag gcagcgcugc      180

cgagaaggag accgagaagg cacccgagug ugaacccgag gagcagggcg gcagggagcc      240

cgagaacaag agggagaagg acagaggaaa gaccaucggg gagcagguug ggggaucgag      300

ggcgaggaag ggcgcugccg ggagggagau ugggagggag agggaggggg agagcgccag      360

agaggguggg aggaaggggg agaggaagag ggacggcggc accgagggcg gcgccggcgg      420

caaggggaag cagaccaggg ccggcgggaa cgauggcggc ggggagcaua acgacgcuac      480

cagcauugcc cgaagacgga ggaucgggcg cauucccgcc agggcauuuu aaagauccga      540

agaggcugua cuguaaaaau ggaggguucu uucugagaau acauccggau ggacggguag      600

auggagugag agagaagagu gacccgcaca uaaaguugca acugcaagcg gaagagagag      660

gaguagugag cauaaaaggg guaugugcca acagauaucu agcaaugaag gaagauggaa      720

ggcuacuggc aagcaagugu guaacggacg agugcuuuuu cuucgaaagg cuagagagua      780

acaacuauaa cacguacaga agcaggaaau auacaaguug guauguggcg cuaaagagga      840

cgggacaaua caagcugggg agcaagacag ggccggggca aaaggcaaua cuguuuuuac      900

caaugagugc gaagaguuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  3378
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt8)

<400>  3378
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aauggauccu aaccuggauc cuacccaccc uucucuaccg auccugcuuc cacaucaucu      120

gccuaguagg aaccaucuca cucgcaugca acgacaugac acccgaacaa auggccacca      180

acgucaacug cuccucccca gaacgccaca cacgcagcua cgacuacaug gaaggcggag      240

acauccgcgu ccgccgccuc uucugccgaa cacaauggua ccuccgcauc gacaaacgcg      300

gcaaaguaaa aggcacacaa gaaaugaaaa acaacuacaa caucauggaa auacgcacag      360

uagccgucgg aaucguagca aucaaaggcg ucgaauccga auucuaccuc gccaugaaca      420

aagaaggcaa acuauacgcc aaaaaagaau gcaacgaaga cugcaacuuc aaagaacuca      480

uccuagaaaa ccacuacaac acauacgcau cagccaaaug gacccacaac ggaggcgaaa      540

uguucgucgc ccucaaccaa aaaggcaucc ccgucagagg caaaaaaacc aaaaaagaac      600

aaaaaacagc acacuuccuc cccauggcca ucaccugagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  3379
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt8)

<400>  3379
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaac       60

uacuccccuc cgucguccuu aaacucuucc ucgccgccgu acucuccgca cucgucacag      120

gcgaaucacu cgaacgacuc cgccgaggcc ucgccgcagg caccucaaac cccgaccccc      180

caaccguguc cacagaccaa cuacuaccac ucggcggagg acgcgaccgc aaaguccgcg      240

accuccaaga agcagaccua gaccuccucc gagucacccu cuccuccaaa ccccaagccc      300

uagccacccc caacaaagaa gaacacggca agcgaaaaaa aaaaggcaaa ggccuaggca      360

aaaaacgcga cccaugccua cgcaaauaca aagacuucug cauccacggc gaaugcaaau      420

acguaaaaga acuccgagcc ccaucaugca ucugccaccc cggcuaccac ggagaacgcu      480

gccacggccu aucccuaccc gucgaaaacc gccucuacac cuacgaccac acaacaaucc      540

ucgccgucgu cgcagucguc cucucauccg uaugccuccu cgucaucguc ggccuacuca      600

uguuccgcua ccaccgacga ggcggcuacg acgucgaaaa cgaagaaaaa gucaaacucg      660

gaaugacaaa cucccacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  3380
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt8)

<400>  3380
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ucaccaagcu acuccccgcu cuccugcuac aacacguccu gcuccaccuc cuacuccucc      120

ccauagccau accauacgcc gaaggacaac gcaagcgccg uaauacaaua caugaguuca      180

agaaaagcgc caaaaccacc cuuaucaaaa ucgaccccgc ccuaaaaauc aagaccaaaa      240

aggugaacac cgccgaccaa ugcgccaaca gaugcaccag aaacaagggc cuccccuuca      300

caugcaaagc cuucguauuc gacaaggccc gcaaacaaug ccuaugguuc ccauucaacu      360

ccauguccuc cggcgucaag aaagaguucg gccacgaauu ugaccucuac gaaaauaaag      420

acuacauccg aaacugcauc aucggcaaag gacgcucaua caaaggcacc guauccauca      480

ccaaaucagg cauaaaaugc caacccugga gcucaaugau cccccacgaa cacucauuuc      540

uaccauccuc cuaccgaggc aaagaccucc aggaaaauua cugcaggaac ccgcgcgggg      600

aagaaggcgg acccuggugc uuuaccucca accccgaagu acgguacgaa gucugcgaca      660

uaccccaaug cuccgaagua gaaugcauga caugcaacgg agaauccuau cggggccuca      720

uggaucacac agaaucaggu aaaaucugcc agcgcuggga ccaccagacc ccucaccgcc      780

auaaauuccu cccagaacgc uacccagaca aaggguucga cgacaacuac ugcagaaacc      840

cugacggcca gccacgccca ugguguuaca cacuagaccc ccacacccga ugggaauacu      900

gcgccaucaa aacaugugca gacaauacaa ugaaugacac cgacguccca cucgaaacca      960

ccgaaugcau ccaagggcag ggagaaggau accgaggcac ggucaacacc aucuggaacg     1020

gcauacccug ccaacggugg gacagccaau auccgcacga acacgacaug acuccagaaa     1080

acuucaaaug caaagaccuc agagagaacu acugcagaaa ucccgacgga uccgaaucac     1140

ccuggugcuu caccacggac cccaacaucc gcguaggcua cugcucacaa auaccaaacu     1200

gcgauaugag ccacggucaa gacugcuauc gcggcaacgg caaaaacuac augggaaacc     1260

ucucacagac ccgcucaggc cuaacgugua gcauguggga caaaaacaug gaggaccuuc     1320

aucggcacau cuucugggaa cccgacgcau ccaaacuuaa cgagaacuac ugccgaaacc     1380

cagacgacga cgcccacggg ccauggugcu acacaggcaa cccacucauc ccgugggacu     1440

auugccccau aagccgcugc gagggcgaca caaccccaac aaucgugaac cuggaccacc     1500

cugucaucuc gugcgcaaaa acaaaacagc uucgggucgu caacggcauc ccaacacgaa     1560

caaacauagg guggaugguc ucucuacgcu acagaaacaa acacaucugc ggcggcucac     1620

ucaucaaaga aagcuggguc cucacagcuc gccaaugcuu cccaucaaga gaccucaaag     1680

auuacgaagc cuggcuaggc auacacgacg uacauggaag gggagacgaa aaaugcaaac     1740

aaguacuuaa cguaagccaa cucgucuaug gcccagaagg aagcgaccuc guccucauga     1800

aacuagcacg cccagccguc cucgacgacu uuguaagcac cauagaccuc cccaacuaug     1860

gcugcaccau cccagagaaa acgaguugcu cagucuacgg cuggggauac acgggacuga     1920

ucaauuacga cggacuacuc cgggucgcac accucuacau caugggcaac gaaaaaugcu     1980

cccaacacca ccgcggcaaa guaacucuca acgaaagcga aaucugcgcc ggagccgaga     2040

aaaucggcuc aggcccaugc gaaggcgacu acggcggacc ccuuguuugc gaacaacaca     2100

aaaugaggau gguacucggc guaauaguuc ccggcagggg gugcgccauc ccaaaccgac     2160

ccggaauauu ugucagagua gcauacuacg cgaaauggau ucacaaaauc auacuaaccu     2220

acaaaguccc ccagucguaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  3381
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt8)

<400>  3381
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aagccgccgc aaucggcaua gaccucggua cgacguacag cugcguaggc gucuuccaac      120

acggcaaggu ggaaauaauc gcuaacgacc aaggcaacag aaccacaccg ucguacgucg      180

cauucaccga caccgaacga cucaucgggg acgcggccaa aaaccaaguc gcacuaaacc      240

cccaaaacac aguguucgac gccaaacgac ucaucgggag aaaauucggc gaccccguag      300

uccaguccga caugaaacac uggcccuucc aaguaaucaa cgacggagau aaacccaaag      360

uacaagucag cuacaaagga gagaccaagg ccuucuaccc agaggaaauc ucaagcaugg      420

ugcugacaaa aaugaaagaa aucgcagaag ccuaccuagg auacccaguc acgaacgccg      480

ucaucaccgu ccccgcauac uucaacgaca gccaaagaca ggccaccaaa gacgccggag      540

ucaucgcagg acucaauguc cuacgaauaa uaaacgagcc aaccgcagcc gccauagcau      600

acggacucga ccgaacaggc aaaggagaac gcaacguccu aaucuucgac cucgggggcg      660

ggaccuucga cgucuccauc cuaacaauag augacggcau cuucgaagug aaagccaccg      720

ccggcgacac acaccucggg ggagaagacu ucgacaaccg ccucguaaac cacuucgucg      780

aagaauuuaa gcgaaaacac aagaaagaca ucagccaaaa uaagcgcgcg gugcgacgcc      840

ugagaaccgc augcgagcga gccaaacgaa cgcucucauc cucaacccaa gcgucacucg      900

aaaucgacuc acucuucgag ggaaucgacu ucuacaccuc aaucacgcga gcccgcuucg      960

aagaauuaug cucagaccuc uuccgaucaa cacuagaacc cgucgaaaaa gcccucagag     1020

augcaaaacu ggacaaagca caaauccaug accuuguccu aguaggaggc ucaaccagga     1080

uccccaaagu acaaaaacug cuccaagacu ucuucaaugg gcgagaccuc aacaagucca     1140

uaaaccccga cgaagcaguc gcauacgggg cagcagucca agcagcaaua uuaaugggcg     1200

acaagucgga aaacguccaa gaccuccuac uacuagacgu cgcgccacua agucuagggc     1260

ucgaaaccgc gggaggcguc augacugccc uaaucaaacg caacuccacc auccccacaa     1320

aacaaaccca aauauucacc acauacuccg acaaccaacc aggaguacug auacaaguau     1380

acgaaggcga acgagccaug accaaagaca acaaccuacu aggacgcuuc gaacucagcg     1440

gaaucccacc cgcccccaga ggaguacccc aaauagaagu cacauucgac aucgacgcaa     1500

acggcauccu aaacguuaca gcgaccgaca aauccaccgg aaaagcaaac aagauaacga     1560

ucacaaacga caaaggcaga cucuccaaag aggagaucga gagaaugguc caagaagcag     1620

agaaauacaa agcagaagac gaaguccaac gugaacgcgu cagcgccaag aacgcacucg     1680

agucguacgc cuucaacaug aaaagcgccg ucgaggacga aggacucaag gggaaaaucu     1740

cagaagccga caaaaagaaa guacucgaca aaugccaaga aguaaucagc uggcuagaug     1800

ccaacacacu cgccgaaaaa gacgaguucg aacacaaacg caaagaauua gaacaagucu     1860

guaaccccau caucuccgga cucuaccaag gcgcaggcgg accaggcccc ggcggcuuug     1920

gcgcacaagg ccccaaaggc ggcagcgguu ccggccccac aauagaagaa guagacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3382
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt8)

<400>  3382
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcaa       60

aagcggcagc aaucggaauc gacuuaggca ccaccuacuc gugcguggga gucuuccaac      120

acggcaaggu ggaaaucauc gcaaacgacc agggcaaccg caccaccccc agcuacguag      180

ccuucacaga caccgaacgc cugauaggag acgcagcgaa aaaccagguc gcacucaacc      240

cacaaaacac agucuuugac gcaaaacggc ucauaggaag aaaauucggc gacccggugg      300

uccagagcga caugaaacac uggcccuucc aggugauuaa cgacggagac aagccgaaag      360

uccaagucuc guacaaaggc gaaaccaagg cauucuaccc ggaagaaauc uccuccaugg      420

uccuaaccaa aaugaaagaa auagccgaag cauaccucgg cuaccccguc accaacgcgg      480

uaauaaccgu ccccgcauac uuuaacgaca gucaacguca ggccaccaaa gacgcagggg      540

ucauagcagg gcucaacguc cuccgaauca ucaacgaacc caccgcagca gccauagcau      600

acggucucga ccgcacaggc aaaggcgaac gaaacguccu aaucuucgac cuaggugggg      660

gcaccuucga cgucucaauc cuaacaauag acgacggcau auucgaagua aaggcaaccg      720

caggcgacac ccaccuaggc ggcgaagacu ucgauaaccg gcucgugaac cacuucgucg      780

aagaguucaa acgcaagcac aagaaagaca uaucgcaaaa caaacgagca guaaggcgac      840

uccgaaccgc gugcgaacga gcaaaaagaa cccuaagcuc gagcacgcag gccagccucg      900

aaauagacuc ccucuucgaa gggaucgacu ucuacacauc aauaacacga gcacgauucg      960

aagaacucug cagcgaucua uuucgcucaa cccucgagcc ggucgaaaaa gcccuccgcg     1020

acgcgaaacu agacaaagcc cagauacacg accuaguccu aguaggggga ucaaccagga     1080

uaccaaaagu acaaaaacua cuccaagacu ucuucaacgg gcgcgaccug aacaaaucua     1140

ucaacccaga cgaagccguc gcguacggcg ccgcugucca agccgcaauu cugaugggag     1200

acaaaaguga aaacguacaa gaucuccugc uacuagacgu agccccacua ucacugggau     1260

uagaaaccgc gggcggaguc augaccgccc uaauaaaaag aaacucaaca aucccaacga     1320

aacaaacaca aaucuucacc accuacagcg acaaccaacc cggagugcuc auccaagugu     1380

acgaaggcga acgcgcaaug acaaaagaca acaaccuccu aggaagauuc gaacuauccg     1440

gcaucccacc agccccacgc ggagucccac agauagaagu cacauuugac auagacgcga     1500

acggaauacu aaacguaaca gcgaccgaca aaucgacggg caaggcaaau aaaauaacca     1560

ucacgaauga caaagggcgc cuaagcaagg aagagaucga aagaauggug caggaagccg     1620

aaaaguacaa ggccgaggac gaaguccaaa gagaacgggu cagcgccaaa aacgcacuag     1680

aaucguacgc cuucaacaug aaauccgcgg ucgaagacga aggacucaaa ggaaaaauaa     1740

gcgaagcuga caaaaagaaa guacucgaca aaugccaaga aguaaucucc uggcucgacg     1800

caaacacauu agccgagaag gacgaguucg aacacaaacg aaaagaacuu gaacaaguau     1860

gcaaccccau uauuucaggc cuauaccaag gagcaggagg gcccgggccc ggaggcuucg     1920

gcgcgcaagg cccaaaagga ggauccggaa gcggaccgac aaucgaagaa gucgacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3383
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt8)

<400>  3383
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcaa       60

ccgccaaggg caucgccauc gggauagacc ucggaacaac cuacucaugc gucggagucu      120

uccaacacgg caaaguggag auaaucgcca acgaccaagg aaaccgaacg acacccucau      180

acguggcguu cacagauaca gagcgguuaa ucggcgacgc agccaaaaac caagucgcca      240

ugaacccaca aaacacgguc uuugacgcca aaaggcuaau uggcagaaaa uucaacgacc      300

ccguagucca ggccgacaug aaacucuggc ccuuccaagu cauaaacgaa ggcggcaaac      360

ccaaaguccu agucucauac aaaggcgaaa acaaagcauu cuacccggaa gaaaucucga      420

gcauggucuu aacaaaauua aaagaaacgg ccgaagcauu ccuuggacac cccgucacga      480

acgcaguaau cacagucccc gcauacuuca acgacuccca acgccaggcg acaaaagacg      540

ccggggucau agccggccua aacguucuga ggauaaucaa cgagccgacc gccgcagcca      600

uagcguacgg acuugacaaa ggaggacaag gcgaacgcca cguacucauc uucgaccugg      660

gcggcggcac cuuugacguc uccaucuuaa ccaucgacga cggcaucuuc gaaguaaaag      720

ccacggccgg agacacacac cuuggcggag aagacuucga caaccggcuc gucagucacu      780

uugucgaaga guucaagcgc aaacacaaga aagauaucuc gcaaaacaaa agagcagucc      840

gaagacuccg caccgccugc gaacgcgcca agagaacacu cagcagcuca acacaggcaa      900

accuggaaau cgacucacuc uacgaaggca uagacuucua caccucaaua acacgagcgc      960

gcuucgaaga acuaugcgcc gaccucuuca gagggacccu ggaaccgguc gaaaaagccc     1020

uccgagacgc caaaauggac aaagcaaaaa uccacgacau aguccuagua ggugggucaa     1080

cccgaauccc caaagugcaa cgacuccucc aagacuacuu caacgggcgc gaccucaaua     1140

aaucaaucaa ccccgacgaa gcaguagcau acggcgcagc aguccaagca gcgauccuaa     1200

ugggggacaa gagcgaaaaa guccaggauc uccuccuccu ugacgucgca ccucuaucuc     1260

uaggacuaga aaccgcaggg gguguaauga cagcacucau caaaagaaac ucaacaauac     1320

ccaccaaaca aacacaaauc uucacaaccu acuccgacaa ccaaccagga guacuaauac     1380

aagucuacga aggggaacgc gccaugacca aagacaacaa ccuccugggc cguuucgacc     1440

uaaccgguau cccaccagca ccacgcggag uaccgcaaau agaagugacg uucgacauag     1500

acgcaaacgg aauccucaac gucaccgcga ccgacaaauc aaccggcaaa gugaacaaaa     1560

ucaccaucac aaacgacaaa gggcgauuaa gcaaagaaga aaucgaacga augguccucg     1620

acgcagaaaa auauaaggcc gaagacgaag uccaacgaga gaaaauagcc gccaaaaacg     1680

cauuagaauc auacgccuuc aauaugaaaa gcguaguauc agacgaaggc cuaaaaggca     1740

aaaucagcga gagcgacaaa aacaagauac uagacaaaug caacgaacuc cuaagcuggc     1800

ucgagguaaa ccaacucgca gaaaaggacg aguucgacca caaaagaaaa gaacuagagc     1860

aaauguguaa cccaaucaua acaaaauuau accaaggagg cugcacgggg cccgccugcg     1920

gaacaggcua ugucccagga agacccgcca ccggccccac gauagaagaa gucgacuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3384
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt8)

<400>  3384
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

cccggggacc cgcaaucggc aucgaccuag gaaccacaua cagcugcgua ggcguguucc      120

aacacggaaa agucgagaua aucgccaacg accaaggaaa ccgaaccacc ccaucauacg      180

uagcguucac cgacaccgaa agacucaucg gggaugcagc gaagaaccag guggcuauga      240

accccacaaa cacaaucuuc gacgccaaac gccuaauagg gagaaaauuc gaagacgcaa      300

caguccaauc agacaugaaa cacuggcccu ucagggucgu cucagaagga ggaaaaccca      360

aaguacaagu cgaauacaaa ggcgaaacaa aaacguucuu cccagaagag aucucaucca      420

ugguccucac aaagaugaag gaaauagccg aagccuaccu aggcggcaaa guccacagcg      480

cagucauaac cguaccagca uacuucaacg acagccaacg gcaagccaca aaagacgcag      540

gaaccaucac cggguuaaac guacuacgaa uaauaaacga acccacagca gcagccaucg      600

cguacggccu cgacaagaaa ggcugcgccg gaggcgagaa aaacguacuc aucuucgacc      660

ucggcggagg cacauucgac guaucgauac ucacaauaga agacggcaua uucgaaguca      720

aaucaaccgc cggagauaca caccuuggag gggaggacuu cgacaacaga auggugagcc      780

accuagcaga ggaguucaaa cgaaaacaca agaaagacau aggacccaac aaaagggccg      840

uacgcagacu cagaacagca ugcgaaagag ccaaacgaac acuaucaucc uccacacagg      900

ccagcauaga aauagacuca cuauacgaag gagucgacuu cuacaccagc aucacacgcg      960

ccagauucga agaacucaac gccgaccuau uccgaggcac ccucgagccg gucgagaaag     1020

cgcuccgaga cgcaaaacuc gacaaaggac aaauacaaga aauaguccuc gucggaggcu     1080

ccacccgaau cccuaaaaua caaaaacuac uccaagacuu cuucaacgga aaagaacuaa     1140

acaaaucaau caaccccgau gaagccguug cauacggcgc cgcuguccaa gcagcaaucc     1200

uaauaggaga uaaaagcgaa aacguacaag accuccugcu acuagacguc accccacucu     1260

cacucggaau cgagaccgcc ggcgguguaa ugaccccacu cauaaaacga aacaccacca     1320

uccccaccaa acaaacacag acguucacca ccuacuccga caaccaauca uccgugcuag     1380

ugcaagucua cgaaggcgaa agagccauga ccaaagacaa caaucuccuc ggcaaauucg     1440

accugacggg cauaccccca gccccacgag gcguccccca aaucgagguc accuucgaca     1500

uagacgcgaa cggcauccuc aacgucacug cugcagacaa aucgacagga aaggaaaaca     1560

aaaucaccau cacaaacgac aaggggcgcc ucagcaaaga cgacaucgac cgaaugguac     1620

aagaagcaga acgcuacaag agcgaagacg aagccaacag agaccgcguc gccgccaaaa     1680

acgcccucga auccuacaca uacaacauaa aacaaaccgu cgaagacgaa aaacuacgcg     1740

gaaaaauaag cgagcaagac aaaaacaaaa uauuagacaa augccaagaa guaaucaacu     1800

ggcucgaccg caaccaaaug gccgaaaaag acgaauacga acacaaacaa aaagaacucg     1860

aacgaguaug caacccgaua aucaguaagc uguaucaagg aggcccagga ggcggaagcg     1920

gcggcggagg uucgggcgcg uccggaggcc caacaauaga agaagucgac ugaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  3385
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt8)

<400>  3385
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

ugguaggcau agaccugggc uuccagagcu guuaugucgc aguagcccgc gcaggcggca      120

uagaaacaau cgcaaacgag uacagcgacc gcugcacacc ggcaugcauc ucguucggac      180

ccaaaaaccg uagcaucggc gcggcagcga aaagccaggu cauaagcaau gcgaaaaaca      240

caguccaggg auucaaacgc uuccacggcc gagcauucuc cgacccauuc gucgaagcag      300

agaaaagcaa ccuggcauac gacaucgucc aguuaccgac cggccuaacc gggaucaaag      360

ucaccuacau ggaagaggaa cgcaacuuca ccacagaaca agucaccgcc augcugcuaa      420

gcaaacugaa agagacugca gaguccguac ucaagaaacc agugguggac ugugucguaa      480

gcgugccgug cuucuacacg gacgccgaac gacguagcgu gauggacgca acacaaauag      540

cgggacugaa cugucuccgc cuaaugaaug aaacgacagc aguagcccuc gcuuacggaa      600

uauacaaaca agaccuaccc gcgcucgaag agaaaccccg caacgucguc uucguggaca      660

ugggacacuc ggccuaccaa gucuccgucu gcgccuucaa ccggggcaaa cugaaagucc      720

ucgccaccgc auucgacacc acacuuggag gccgaaaauu cgacgaaguu cucgucaacc      780

acuucugcga agaguucggg aagaaauaca aacuugacau aaaauccaaa auccgagcac      840

ugcuccgacu cagucaagaa ugcgaaaaac uaaagaagcu cauguccgcg aacgccagcg      900

accucccccu auccaucgaa ugcuuuauga acgacgucga cgucuccgga accaugaacc      960

gagggaaauu ccuagaaaug ugcaacgacu uacuagcgag aguagaacca ccccuacgaa     1020

gcguacuaga acagaccaaa uuaaagaaag aagauaucua cgcaguagaa auagugggcg     1080

gagcaacccg cauacccgcc guaaaagaga aaaucucaaa auucuuuggc aaagaacucu     1140

cgacaacacu aaacgccgac gaagcaguga cccgcgggug cgccuugcaa ugcgcaauuc     1200

ucagccccgc uuucaaagua agagaauuuu caauaacaga cgucguacca uaccccauau     1260

cacuccgcug gaacucccca gcagaagaag gaagcuccga cugcgaaguc uucuccaaaa     1320

accacgcagc ccccuucucu aaaguccuca ccuucuaccg gaaagaaccc uucacccuag     1380

aagccuacua cucgucacca caggaccuac cauaucccga ccccgcaauc gcgcaauucu     1440

ccguccaaaa aguaacaccc cagagcgacg ggagcagcag caaaguuaaa guaaaaguac     1500

guguaaacgu acacggaauc uucucagucu ccucagccuc ccucgucgaa guccacaaaa     1560

gcgaagaaaa cgaagaacca auggaaaccg accagaaugc aaaagaagaa gagaaaaugc     1620

aagucgacca agaagaaccc cacgucgagg agcaacaaca acaaacucca gccgaaaaca     1680

aggccgaauc agaagaaaug gagaccucac aagccggguc aaaagacaag aaaauggauc     1740

aaccgcccca agcgaagaaa gcgaaaguca aaacauccac agucgaccuc cccauagaga     1800

accaacugcu cuggcaaauc gaccgcgaga ugcucaaccu cuacaucgag aacgaaggaa     1860

aaaugaucau gcaggacaaa cuagaaaaag aaaggaacga cgccaaaaac gccguggaag     1920

aguacgucua ugaaaugcgc gacaaauuaa gcggagagua cgagaaauuu gucuccgaag     1980

acgacagaaa cuccuucaca cuuaaacucg aagacaccga aaacuggcua uacgaagacg     2040

gcgaggacca gcccaaacaa guauacgugg acaaacucgc agagcugaaa aaccuaggac     2100

aacccaucaa aauccgauuu caagaaagcg aagaacgccc caagcuguuc gaggaacucg     2160

gaaaacaaau ccaacaauac augaaaauca uaucauccuu caaaaacaaa gaggaccaau     2220

acgaccaccu cgacgccgca gauaugacga aaguagaaaa guccaccaac gaagcgaugg     2280

aauggaugaa caacaaacuc aaccuacaaa acaaacaauc gcucacaaug gaucccgugg     2340

uaaagagcaa ggagaucgag gcaaaaauua aagaacucac auccacaugc agccccauaa     2400

ucucaaaacc caaaccaaag gucgaaccgc caaaagaaga acagaagaac gccgagcaaa     2460

acggcccagu agacggccaa ggcgacaacc caggccccca agcagcggaa cagggaaccg     2520

acacggccgu ccccucagau ucggacaaga aacucccaga aauggacauc gacuaaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  3386
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt8)

<400>  3386
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucag       60

uggucggcau cgaccuaggc uuccucaacu gcuacaucgc cgucgcccgc uccggcggga      120

uugaaacaau cgcaaacgag uacucggaca ggugcacacc cgcuugcaua ucacugggau      180

cgcggacgcg cgccauagga aacgcagcca aaagccagau cguaacaaac gugcgcaaca      240

ccauccaugg cuuuaaaaag cuccacggca ggagcuucga cgaccccauc guucaaaccg      300

agcgcaucag acuaccauac gaauuacaga aaaugcccaa cggcagcgcc gggguaaaag      360

uccgcuaccu cgaagaagaa cgaccuuucg cgaucgaaca aguuaccgga auguuacuag      420

caaaacugaa ggaaaccuca gagaacgccc ucaagaaacc cguggcagac ugcguaauau      480

caaucccuag cuucuucaca gacgcagaaa gacguucagu aauggcggca gcccaaguag      540

cagggcucaa cugccuccga cuaaugaacg aaacaacagc cguggcccuc gccuacggca      600

uauacaaaca agaccugccg ccacuagacg aaaagccccg caacgucgug uucauagaca      660

ugggacacag cgccuaccaa guccucgucu gcgccuuuaa caagggcaaa cucaaagucc      720

ucgccacgac auucgacccc uaccugggcg gacgcaauuu cgacgaagcu cucguagacu      780

acuucugcga cgaguucaaa acaaaauaca aaaucaacgu caaggaaaac ucaagagccc      840

ugcuccgacu auaucaagaa ugcgagaaac uaaagaaacu cauguccgcg aacgccagcg      900

accucccacu aaacaucgaa uguuuuauga acgaccugga cgucagcucc aaaaugaacc      960

gcgcccaguu cgaacaacuc ugcgccagcc uacuagcacg cguggagcca ccccucaaag     1020

ccguaaugga acaagcgaac cuccagcgcg aggacauauc aagcaucgag auaguaggcg     1080

gcgcgacgcg cauccccgcc guaaaagagc aaaucacaaa auucuuccuc aaagacauuu     1140

caacaacacu uaaugcagac gaagcaguag ccaggggaug cgcucuacaa ugcgccaucc     1200

ucagcccggc auucaaagua cgcgaguucu ccaucacaga ccuagucccc uacucaauca     1260

cacucagaug gaaaaccuca uucgaagacg ggagcggaga augcgaagua uucugcaaaa     1320

accacccugc cccauucagc aaagugauaa cguuccacaa gaaagaaccc uucgaacuug     1380

aagcguucua cacaaaccuu cacgaagucc ccuacccuga ugcgcgaauc gguucauuca     1440

caauacagaa cguauucccc caaagcgacg gcgacucgag caaaguaaaa gucaaagucc     1500

gcguaaacau ccacggcauc uucucaguag caagugccag cgugaucgaa aaacaaaacc     1560

ucgaaggcga ccacagcgac gcccccaugg agacagaaac aucguucaaa aacgaaaaca     1620

aagacaacau ggacaaaaug cagguagacc aagaagaagg ccaccagaag ugccacgccg     1680

aacacacacc cgaagaagaa aucgaccaca ccggcgccaa aacaaaaucg gcagucuccg     1740

acaaacaaga ccggcuaaac caaacccuca agaaaggcaa aguaaaauca aucgaccuac     1800

ccauacaguc cucacucugc cgccaacugg gccaagaucu ccuaaacuca uacaucgaaa     1860

acgaaggaaa aaugauaaug caagacaaac ucgaaaaaga acggaacgac gccaaaaacg     1920

cgguagagga guacgucuac gacuuucggg accgacuggg cacgguuuac gaaaaauuca     1980

ucacacccga agaccuaagc aagcuaucug cgguccugga agauaccgag aacuggcucu     2040

acgaagacgg cgaagaccaa ccaaaacaag uguacguaga caagcugcag gaacugaaga     2100

aauaugggca accaauccaa augaaauaca uggaacacga agaaaggccc aaagcacuga     2160

acgaccuagg caagaaaauu caauuaguca ugaaagugau cgaagcguac agaaacaaag     2220

acgaaagaua cgaccaccuc gacccuacag agauggagaa aguagagaag ugcauaucag     2280

acgccauguc cuggcuaaac agcaagauga acgcccaaaa caaacucagc cuuacgcaag     2340

accccguggu caaagucuca gaaauaguug cgaaaucaaa ggagcuagau aacuucugca     2400

accccauaau auacaaaccg aagcccaaag ccgaaguccc cgaagacaag cccaaagcca     2460

acagugaaca uaacgggccg auggacggac agucaggcac ugagaccaaa agcgacucga     2520

caaaagacag cagucaacac acaaagucgu ccggagagau ggaagucgac uaaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  3387
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt8)

<400>  3387
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaac       60

ucagccuagu cgcagccaug cugcugcucc ucagcgcagc acgggcagaa gaggaagaca      120

agaaagaaga cgugggaaca guaguaggca uagaccucgg aacgacauac agcugcguag      180

ggguauucaa aaacggacga gucgagauca uagccaacga ccagggcaac agaauaaccc      240

caaguuacgu agcguucaca cccgagggug aacgacugau cggagacgca gcgaaaaacc      300

aacucacaag caaccccgaa aacacaguau ucgacgcaaa gcgacuaaua ggccgcaccu      360

ggaacgaccc cucgguccag caagacauca aauuccugcc auucaaaguc gucgagaaga      420

aaacaaaacc cuacauacaa guagacauag ggggcgggca gacgaaaacg uucgcgccag      480

aagaaauaag cgcaauggua cugacgaaaa ugaaagagac cgcagaagcg uaccugggca      540

agaaagucac ccacgcaguc guaacagugc cagccuacuu caaugacgcg caacgacaag      600

caacaaagga cgcaggaaca aucgcgggac ugaacgugau gcgaaucaua aaugaaccca      660

ccgccgccgc aauagcguac ggacuagaca aacgggaagg cgagaaaaac auccuagucu      720

ucgaccuggg cggagguacc uucgacguaa gucuccugac aaucgacaac ggcguauucg      780

aagucguagc aacaaacggg gacacacacc ugggaggaga agacuucgac cagcgaguaa      840

uggagcacuu cauaaaacua uacaagaaga aaaccggaaa agacguaagg aaagacaaca      900

gagccguaca aaaacucagg cgggaggucg aaaaagccaa acgcgcccua uccagccaac      960

accaagcgcg caucgaaaua gaaucauucu acgaggggga agacuucagc gaaacccuaa     1020

cacgcgcaaa auucgaagaa cugaacaugg accuauuccg cagcacgaug aaaccaguac     1080

aaaaaguccu agaggacagc gaccuaaaga aaagcgacau agacgaaaua guauuagugg     1140

gcggcucgac caggauacca aaaauacaac aacugguaaa agaguucuuc aacggcaaag     1200

aaccaucgcg agggaucaac ccagacgaag ccgucgcaua cggagccgca guucaagcag     1260

gaguacugag cggcgaccaa gacacaggag accucguacu acuggacgug ugcccacuca     1320

cccuaggcau agaaacagua ggcgggguaa ugacaaaacu cauaccaaga aacacggucg     1380

ugcccaccaa gaaaagccag auauucagca cggcaagcga caaccaaccc accguaacga     1440

ucaaagucua ugaaggagaa cgaccccuca caaaagauaa ccaccuacug ggcaccuucg     1500

aucuaacagg cauaccacca gccccaagag ggguaccaca aauagaagug acauuugaaa     1560

ucgacguaaa cgggauucuc cgagugaccg cggaagacaa aggaaccgga aacaaaaaca     1620

aaauaacgau aaccaacgac caaaacagac ucacaccgga agaaaucgaa agaaugguca     1680

acgacgcaga gaaauuugcc gaagaggaca agaaauugaa agagcgaaua gacaccagaa     1740

acgaacucga aagcuacgcc uacucacuca aaaaccagau aggugacaaa gaaaaacuag     1800

gagggaaacu aagcagugaa gacaaagaaa ccauggaaaa agccgucgaa gagaaaaucg     1860

aauggcuaga aucacaccaa gacgcagaca uagaagacuu caaagccaaa aagaaagaac     1920

uagaagaaau aguacaacca aucauaucca aacuauacgg aagcgcaggg cccccaccca     1980

caggagaaga ggacacagcg gaaaaagacg aacuauaagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  3388
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt8)

<400>  3388
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

caccccggga gcucgcaguc ggcauugauc ucggaacaac auacuccugc guaggagugu      120

uccagcaagg gcgcguggaa auacucgcaa acgaccaagg caaccggacc accccaagcu      180

acguggccuu caccgacaca gagcggcugg uaggagacgc agcaaaaagc caagccgcgc      240

ugaaucccca caacacaguc uucgacgcaa aaaggcuaau uggaagaaaa uucgcagaca      300

caacaguaca aagcgacaug aaacauuggc ccuuccgagu cgucucagaa gggggcaaac      360

ccaaggucag agucugcuac agaggugaag acaaaacauu cuaccccgaa gagauaucaa      420

gcauggugcu cagcaaaaug aaagagacgg ccgaggcaua ccucgggcaa ccggucaaac      480

acgcgguaau aacaguccca gcauacuuca acgauagcca acgccaagcc acaaaagacg      540

ccggagcaau cgccgggcuc aacguccuac gaauaaucaa cgaaccaaca gcggcagcaa      600

ucgcuuacgg gcuagacaga agaggcgcag gcgaacggaa cguccugaua uucgaccuag      660

gaggaggaac auucgacgua ucagugcuaa gcaucgacgc aggaguauuc gaagucaaag      720

ccacggcagg agacacacac cugggcgggg aagacuucga caacaggcua guaaaccacu      780

ucauggaaga guuccggcgc aaacacggga aagaccuauc agggaacaaa agagcccugc      840

gaaggcugag aacagccugc gaacgcgcaa aaaggacacu aagcagcucc acacaagcaa      900

cacuagaaau agacucccuc uucgaaggag ucgacuucua uaccucgauc acgcgcgcac      960

gauucgaaga acuaugcagc gaccucuucc gaucgacccu ggaaccggua gaaaaagccc     1020

uaagagacgc gaagcuagac aaggcccaaa uacacgacgu aguccucgua ggaggaucga     1080

cacgcauccc aaaaguacaa aaacuccuac aagacuucuu caacgggaaa gaacucaaca     1140

agucaauaaa ccccgacgaa gcaguggccu acggugccgc aguucaggcc gcaguccuga     1200

ugggcgacaa gugcgaaaag guucaagacc uacuacuccu agacguggca ccccucuccc     1260

ucggacuaga gacagcgggc ggagucauga cuacacuaau ccaaagaaac gcaaccaucc     1320

caacaaagca aacacaaaca uucacaaccu acucagacaa ccaaccaggc guauucaucc     1380

aagucuacga gggcgaacgc gcaaugacca aagauaacaa ccuacugggc cgauucgagc     1440

ucucaggcau acccccagca ccccgaggag ucccacaaau agaaguuaca uucgacaucg     1500

acgccaacgg gauauugagc gugaccgcaa cagaccgcuc aaccggaaag gcaaacaaaa     1560

uaacaauaac aaacgauaaa ggacgacuaa gcaaagaaga aguggagcgc augguacacg     1620

aggcggaaca auacaaggcc gaggacgaag cccaacggga cagaguagcc gccaaaaaca     1680

gccuggaagc gcacgucuuc cacgucaaag gaucacuaca ggaagaaucc cuccgagaca     1740

aaauacccga ggaagacaga cgaaaaaugc aagacaagug ccgagaaguc cuagccuggc     1800

ucgaacacaa ccaacuggcc gaaaaagaag aauacgaaca ccaaaagcga gaacuagagc     1860

aaauaugcag accaauauuc ucgagacuau acggcgggcc gggcguaccu ggcggaucga     1920

gcugcggcac ccaagcccga caaggcgacc caucaaccgg gccuauaauc gaggaagugg     1980

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  3389
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt8)

<400>  3389
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

caccacgcga acucgcaguc ggaaucgacc uaggcaccac auacucaugc gucggcguau      120

uccaacaagg aagagucgaa auccucgcca acgaccaagg aaaccgaacc acgccaagcu      180

acgucgcauu cacagacaca gaacgccugg ucggcgacgc agccaaaagc caagccgcac      240

ucaacccaca caacacagua uucgacgcaa aacggcucau aggccgcaaa uucgccgaca      300

ccaccgucca aagcgacaug aaacauuggc cauuccaagu cguaagcgaa ggcggcaaac      360

ccaaaguccg agucugcuac agaggcgagg acaaaacauu cuacccagaa gaaaucucca      420

gcaugguacu aaguaaaaug aaagaaaccg cagaagcaua ccuaggccaa cccguaaaac      480

acgcaguaau aaccguacca accuacuucu caaacagcca acgccaagca acaaaagacg      540

caggagccau cgccggccuc aaaguccucc caauaauaaa cgaagcaacc gcagccgcaa      600

ucgccuacgg acucgaccga cgaggcgccg gcaaacgaaa cguacucaua uucgaccucg      660

gcggcggcac cuucgacgua agcguacuaa gcaucgacgc aggagucuuc gaagucaaag      720

caacggccgg cgacacacac cuuggaggag aagacuucga caacagguua gucaaccacu      780

ucauggaaga guuccgccgc aaacacggaa aagaccucuc aggaaacaaa cgcgcacugc      840

gacggcuacg aacagcgugc gaacgcgcaa aacgcacccc cuccagcagc acacaagcca      900

cucucgaaau cgacucacug uucgaaggcg ucgacuucua caaauccaua acacgcgcac      960

gcuucgaaga acucugcagc gaccucuucc gcagcacccu cgaacccguu gaaaaagccc     1020

uacgcgacgc caaacuagac aaagcccaaa uccacgacuu cguccugggc ggcggccucc     1080

acucacaccc ccaaggagcc gaaguagcag caggacuccu gcaacgccaa ggagcagaac     1140

aagaacacca acccuaggga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  3390
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt8)

<400>  3390
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagca       60

aaggaccagc aguagggaua gaccucggaa ccacauacuc cugcguaggg guauuccagc      120

acggcaaagu agaaauaaua gcgaacgacc aaggcaaccg gaccaccccu uccuacguag      180

ccuucaccga cacagagcgc cucaucggag acgcggccaa aaaccaaguc gcaaugaacc      240

ccaccaacac aguauucgac gcaaaaagac ucauaggcag gcgguucgac gacgcagucg      300

uacaaagcga caugaagcac uggcccuuca uggucguaaa cgacgcagga cgcccaaaag      360

uccaaguaga auacaagggc gagacaaaau ccuucuaccc agaagagguc uccagcaugg      420

uacugaccaa aaugaaagag auagcagaag ccuaccucgg aaaaacugua accaacgcag      480

uagucacagu cccagccuac uucaaugaca gccaacgcca ggccaccaaa gacgccggaa      540

ccaucgccgg acuuaacgua cuacgcauca ucaaugagcc aacggcggcc gcaaucgcgu      600

acgggcucga caaaaaggua ggagccgaaa gaaacguccu gaucuucgac cuaggaggag      660

gaacauucga cgucucaauc cucacaauag aagacggcau auucgaagua aagagcacgg      720

ccggcgacac acaccuggga ggagaagacu uugacaacag aaugguaaac cacuucauag      780

cagaguucaa gcgcaagcac aagaaggaca ucagcgaaaa caaaagagca guacgccgcc      840

uccgcaccgc cugugaaaga gcaaaacgca cccucagcuc cagcacccaa gcaaguauag      900

aaauugacuc acuauacgaa ggcaucgacu ucuacaccag caucacccga gcaagauucg      960

aagaauuaaa cgcagaccuc uucagaggaa cccuggaccc agucgagaaa gcacuacgag     1020

acgcaaaacu agacaaaagu caaauacacg acauaguccu agucggaggc agcacacgaa     1080

ucccgaagau acagaaacuc cuccaagacu ucuucaacgg aaaagaacua aacaaaagca     1140

uaaauccaga cgaagcaguc gcauacggcg cagcggucca agcggccaua cuuucaggcg     1200

acaaaagcga gaacguacaa gaccugcugc uccuggacgu cacgccgcuc ucacuaggca     1260

ucgaaacagc cggcggcgua augaccgugc ucauaaaacg caacacaacc auaccaacaa     1320

aacagaccca gaccuucacg acauacuccg acaaccagcc aggcguacuc auacaggucu     1380

acgaaggaga acgcgcaaug acaaaagaca acaaccuccu aggcaaauuc gaacucacag     1440

ggauaccccc agcaccgcgc ggagucccac aaauagaagu caccuucgac aucgacgcaa     1500

acggaauccu aaacguaucc gccguagaca aaucaaccgg aaaagaaaac aaaauaacga     1560

ucacaaacga caaaggccgc cuaagcaagg aggacaucga gagaaugguc caggaggccg     1620

aaaaauacaa agccgaagac gaaaaacaac gcgacaaagu aaguagcaag aacagccugg     1680

aaagcuacgc auucaacaug aaggcgacgg ucgaagacga aaaacugcag ggaaaaauaa     1740

acgacgaaga caaacagaaa auccuagaca aaugcaacga aaucauaaac uggcuggaca     1800

aaaaucaaac cgccgaaaaa gaagaauuug aacaccaaca aaaggagcuc gaaaaagugu     1860

gcaaucccau aaucaccaaa cuauaccaau cagcgggagg aaugcccgga gggaugccgg     1920

gcggguuccc aggaggggga gcacccccaa gcggaggcgc aagcucgggc cccacgauag     1980

aggaggucga cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  3391
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt8)

<400>  3391
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauau       60

cagccagccg cgcggccgcc gcaagacugg ugggagcagc cgcgagccgc ggaccaacag      120

cagcgcggca ccaagacagc uggaacggac ugucacacga agcauuccga cucgugagua      180

gaagagacua cgcgagcgaa gccauaaaag gggccguagu cggaaucgac cucggaacaa      240

caaauaguug cguagccgug auggagggaa aacaagccaa aguacuagag aacgcggagg      300

gagcgagaac cacaccaagc gucguagccu ucaccgcaga uggagaaagg cucguaggca      360

ugcccgcaaa aagacaagca gugacgaacc caaacaacac cuucuacgcg acaaagcgcc      420

ucaucggccg acgcuacgac gaccccgagg ugcaaaaaga caucaaaaac guaccauuca      480

aaauagugag agcaagcaac ggcgacgccu gggucgaagc ccacggcaaa cuauauagcc      540

ccagccagau aggggccuuc gucuugauga aaaugaaaga gaccgcagaa aacuaccuag      600

gacacacagc caagaacgca guaauaaccg uaccugcaua cuucaacgac agccagagac      660

aagccacaaa ggacgccggc cagauaagcg gacuuaaugu acuacgcgua auaaacgaac      720

cgacagccgc cgcgcucgca uacggccuag acaaaagcga ggacaaagua auagcaguau      780

acgaccuagg agggggaacu uucgacaucu cgauacuaga aauacaaaag ggaguuuucg      840

aggucaaguc aacaaacggg gacaccuucu uaggcggaga agacuucgac caagcgcugc      900

uacgccacau cgugaaagag uucaaaagag aaacaggggu cgaccucacg aaagacaaca      960

uggcacucca aagagucaga gaagcggcag aaaaagcgaa augcgaacua agcagcagcg     1020

uccaaacaga cauaaaccua cccuaccuaa caauggauag cucaggccca aaacaccuga     1080

acaugaagcu cacgcgcgcg caauucgagg ggauagugac ugaccucauc agaagaacca     1140

uagcaccaug ccaaaaagca augcaagaug ccgaaguaag caaaagcgac auaggggaag     1200

ucauccuagu cggaggaaug acgaggaugc caaaaguaca acaaacagua caagaccucu     1260

ucgggagagc cccguccaag gccguaaacc cggacgaggc aguagccaua ggagcggcca     1320

uacaaggagg aguccuagcc ggggacguaa cagacgugcu gcugcucgac guaacacccc     1380

ugucucuggg cauugaaacc cuaggaggcg uuuucacaaa acucaucaac agaaacacga     1440

cgauaccgac uaagaaaucc caagucuucu ccacagccgc cgacggucaa acccaaguag     1500

aaaucaaagu cugccaagga gagagggaaa uggccgggga caacaaauua cucgggcaau     1560

ucacccucau cggaauccca cccgcgcccc gaggcgugcc ccagauagag gucacauucg     1620

acaucgacgc caacggaaua guacacguaa gcgccaaaga caaaggaaca ggccgggaac     1680

aacagauagu cauacaguca agcggaggcc ucagcaagga cgacaucgaa aacaugguca     1740

aaaacgcaga gaaguacgca gaagaggacc ggagaaagaa agaacgcgug gaagcaguaa     1800

acauggccga agggauaaua cacgacaccg agacaaaaau ggaggaguuc aaagaccagc     1860

ugcccgcgga ugaauguaau aaacuaaaag aagaaauaag caaaaugagg gaacuacucg     1920

cacgaaagga cucugaaacg ggcgagaaca uuagacaagc ggcaagcagc cuccaacaag     1980

caucccugaa gcucuuugaa auggcauaca agaaaauggc gucggaaagg gaaggguccg     2040

ggagcucagg cacgggagag caaaaggaag accaaaagga ggaaaaacaa uaaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  3392
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt8)

<400>  3392
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcgg       60

acaaagaagc cggaggaagc gacggccccc gcgaaaccgc cccaacaucc gccuacagcu      120

cgcccgcccg cagccuagga gacaccggaa ucacaccccu cucucccucc cacauuguca      180

acgacaccga cuccaacgua ucugaacaac aaucauuccu cguaguaguc gcaguagacu      240

ucggcaccac cucguccgga uacgcauacu cguucaccaa agaacccgaa uguauccacg      300

uaaugagacg cugggaaggc ggcgaccccg gggucuccaa ccagaaaacc ccaaccacca      360

uacuacucac cccagaaaga aaauuccacu ccuucggaua cgccgcccgc gacuucuacc      420

acgaccucga ccccaacgaa gccaagcaau ggcucuacuu ggaaaaauuc aaaaugaaac      480

uccauacaac cggagaccuc accauggaca ccgaccucac agcugcaaac ggcaagaaag      540

ucaaagcacu cgagaucuuu gccuacgcgc ugcaauacuu caaagaacaa gcccucaaag      600

aacucuccga ccaagcaggg ucagaguucg aaaauagcga cguccgaugg gucaucaccg      660

ucccagcaau uuggaaacaa cccgcaaaac aauucaugcg ccaagccgcc uaccaagcug      720

gccuagcuuc accagaaaac ucagaacaac uaaucauagc acucgaaccg gaagcagcaa      780

gcaucuacug cagaaaacua cgccuccacc aaaugaucga acucagcuca aaagccgccg      840

ugaacggcua cuccggaucc gacaccguag gcgcgggcuu cacacaagcc aaagaacaca      900

uccgucggaa ccgccaauca cgaacauucc uagucgaaaa cgucauaggc gaaaucugga      960

gcgaacuaga agaaggcgac aaauacgucg uagucgacuc aggcggaggc acaguggacc     1020

ucaccguaca ucaaauccgc cuaccagaag gccaccucaa agaacucuac aaagcuacag     1080

gcggaccaua cggaucacug ggcgucgacu acgaguucga aaaacuacua uacaagaucu     1140

ucggcgaaga cuuuaucgaa caauucaaaa ucaaaagacc cgccgccugg guagaccuca     1200

ugaucgccuu cgaauccaga aagagggcag ccgcgcccga ccgcacuaac ccccugaaca     1260

uaacacuccc auucagcuuc aucgacuauu acaagaaauu ccgcggccac ucaguugaac     1320

acgcccuccg caaauccaac guagacuuug uaaaaugguc aucccaaggc augcuccgga     1380

ugucccccga cgccaugaac gcccuauuca aaccaaccau agauuccaua aucgaacacc     1440

ucagagaccu cuuccaaaaa cccgaagucu caaccguaaa auuccuuuuc cuagucgggg     1500

gauucgccga agcgcccuua cuacaacaag cggugcaagc ugcauucggc gaucaaugcc     1560

gaauaauaau cccccaagac guaggccuaa ccauacugaa aggggcagua cucuucggcc     1620

ucgaccccgc aguaaucaaa guccgacgcu ccccacuaac cuacggcgua ggcguacuca     1680

acagauacgu agaaggaaaa cauccaccag agaaacuccu gguuaaagac ggaaccagau     1740

ggugcaccga cguauucgac aaauucauca gcgccgacca aucaguugca cucggcgaau     1800

uaguuaagcg aagcuacacc cccgcgaaac caucccaacu cgucaucguc auaaauaucu     1860

acagcucaga acacgacaac gucucguuca ucaccgaccc cggggucaaa aagugcggca     1920

cgcucagacu cgaccucacc ggcaccagcg ggacggcagu accagcgcga cgcgagauac     1980

aaacccucau gcaauucggc gacacagaga ucaaagccac cgcgauugac auagcaacau     2040

caaaaucugu caaagucgga aucgacuucu uaaacuacua aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  3393
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt8)

<400>  3393
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcucg       60

ccguccccga gaugggcuug cagggccuau acauaggcag cucacccgaa agaagcccag      120

ucccaucccc accuggaucc cccagaaccc aagaauccug cggaaucgcu ccccucaccc      180

caucacaauc cccaaaaccg gaaguccgcg caccccaaca ggccucauuc ucaguuguug      240

ucgccauaga cuucggcaca accucaagcg gauacgccuu cagcuucgcc ucagaccccg      300

aagccauaca uaugaugcgc aaaugggagg guggcgaccc cggcgucgcc caccagaaaa      360

cgcccacuug ccuacuccuc accccagaag gcgccuucca cuccuucggc uacacggcca      420

gagacuacua ccacgaccuc gaccccgaag aagcaaggga cugguuguac uucgaaaaau      480

uuaaaaugaa aauucauagc gccacagacc uaacccuaaa aacgcaauua gaagcuguaa      540

acggcaaaac caugcccgcc cucgaagucu ucgcccacgc acuccgcuuc uuccgagaac      600

acgcacucca agaacuaaga gagcaaucac ccagccuccc cgagaaagac acaguacgcu      660

ggguacugac cguacccgcc auauggaagc aaccagcgaa acaauucaug agagaggccg      720

cauaccucgc agggcuagua ucccgggaaa acgcagaaca acuccucaua gcauuagaac      780

cagaagcagc cucagucuau ugcagaaaac uccgccugca ccaauugcuc gaccucagcg      840

gccgcgcccc aggaggcggu cgacucggcg aacgacgaag cauagacuca ucauuccgcc      900

aagccagaga acagcuccgc cgauccagac acucacgaac cuuccuugua gaauccggcg      960

ucggagagcu uugggccgaa augcaagccg gggaccgaua cgucguagcc gacugcggcg     1020

gcggaaccgu cgaccuaaca guacaccaac uagaacaacc acaugguacc cucaaagaac     1080

ucuacaaagc cuccggcggu cccuacggag ccguuggcgu agaccucgca uucgaacaac     1140

uacucugcag aauauucgga gaagacuuua uagcuaccuu uaaaagacaa cgacccgcag     1200

ccugggucga ccuaacuaua gccuucgaag cacgcaaacg aacagccggc ccacacagag     1260

ccggcgcacu caacauaagc cuaccauucu cguucauaga cuucuaccgc aagcaaagag     1320

gccacaacgu cgaaaccgcc cucagacgau cauccguaaa cuucguaaaa uggucaaguc     1380

aaggaaugcu gcgaauguca ugcgaagcaa ugaacgagcu auuccaaccg acaguaagcg     1440

gaaucaucca acacaucgaa gcgcuccuag cgcgcccuga aguccaaggc guaaaacuuc     1500

uauucuuagu uggaggauuc gcagaaagcg ccguacuuca acaugcaguc caagcagcac     1560

ucggcgcacg cgggcuccga gucgucgucc cccacgacgu uggccuaacc auacucaaag     1620

gagccguccu cuucggacaa gccccagggg ucguccgagu gcgcagauca ccgcuaacau     1680

acggcguagg cgugcucaau cgcuucguac caggcagaca cccgcccgaa aaacuccuag     1740

uccgagacgg acggcgcugg ugcaccgacg ucuucgaaag auucgucgcg gcugaacaau     1800

ccguagcccu cggcgaagag guacgucgca gcuacugccc agcccgaccc ggacagagac     1860

gaguucucau caaccucuac ugcugugcag cagaagacgc ccgguucaua acagaccccg     1920

gcguaagaaa augcggagca cucucccuug aacuagaacc ggcagacugc ggacaagaca     1980

ccgccggcgc cccacccgga agacgcgaaa ucagagccgc aaugcaauuc ggagacacag     2040

aaaucaaagu cacagcagua gacguaagca ccaacagaag cgucagagca agcauagacu     2100

uccucucaaa cuagggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  3394
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt8)

<400>  3394
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

gcgaaaugac cauacuaggc uccgccguau uaacccuccu ccuugcaggc uaccuagcac      120

aacaauaccu cccacuacca accccaaaag ucauuggcau ugaccucgga accacguacu      180

gcagcgucgg cgucuucuuc ccuggaaccg gcaaagucaa aguaauaccc gacgaaaacg      240

gccacaucuc cauaccaucc augguuuccu ucaccgacaa cgacguguac gucggauacg      300

aauccgucga acucgccgac agcaacccac agaacaccau cuaugacgca aaacgauuca      360

ucggaaaaau auucacagcc gaagaacucg aagccgaaau cggacgcuau ccauucaaag      420

uacuaaacaa aaacggcaug guagaguucu ccgucacaag caacgaaacc aucaccguca      480

gccccgagua cguaggaucu agacugcuuc uaaaacuaaa agaaauggcc gaagccuauc      540

ugggcaugcc cgucgccaac gcaguaaucu cgguccccgc agaguucgac cuaaaacaac      600

gaaacucaac cauagaagcg gccaaccuag ccggccucaa aauacuaaga gucauaaacg      660

aacccacugc cgcggcuaug gccuacgguc uccacaaagc cgacgucuuc cacguccucg      720

ucaucgaccu cggcggcgga accuuagacg ucagccuacu caacaaacaa ggcggcaugu      780

uccucacccg cgcaaugagc ggcaacaaca aacucggagg ccaagacuuc aaccaacgcc      840

uacuccaaua ccucuacaaa cagaucuacc aaaccuacgg cuuuguacca ucccgcaaag      900

aagaaauaca ccgacuccga caagccgucg aaauggucaa acucaaccug acccuacacc      960

aaagcgccca gcuaucugua cuacuaaccg ucgaagaaca agaccgcaaa gaaccccacu     1020

caagcgacac cgaacucccc aaggacaaac ucagcucugc ggacgaccac cgcgucaacu     1080

ccggcuucgg ccgaggcuua ucagacaaga aauccggaga aagccaaguc cucuucgaaa     1140

ccgagauauc ccgcaaacua uucgacacac ucaacgaaga ccuauuccag aaaaucuuag     1200

uacccauaca acaaguccuc aaagaaggcc accuggagaa aacagaaaua gacgaagucg     1260

uccuaguagg cggcagcaca cgcauccccc gcauuagaca agucauccaa gaguucuucg     1320

gcaaagaccc caacaccucc gucgaccccg accuagccgu cgugaccggg guagcaaucc     1380

aagccggcau cgacggaggc uccuggccac uacaggucuc ggcacuugaa aucccgaaca     1440

aacaccucca gaaaaccaac uucaauuaag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3395
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt8)

<400>  3395
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

caaucggcgu ccaccucgga ugcacaucag ccugcgucgc cgucuacaaa gacgggcgcg      120

ccggcgucgu cgcaaacgac gcgggcgacc gcgucacacc agccgucguc gcauacuccg      180

aaaacgaaga aauaguaggc cuagccgcca agcaaucccg cauacgcaac aucagcaaca      240

cagucaugaa aguaaaacaa auauuaggcc gcuccuccuc cgacccacag gcccaaaaau      300

acaucgcaga aucaaaaugc cucguaaucg agaaaaacgg caaacuacgc uacgagaucg      360

acacuggcga agaaaccaag uucguaaacc cagaagacgu cgcccgccua aucuucucaa      420

aaaugaaaga aacggcccac ucaguccucg gcuccgacgc caacgauguc gucauaaccg      480

uaccauucga cuucggcgaa aaacaaaaga acgcacuagg cgaagccgcc cgcgcagcgg      540

gauucaacgu ccuacgccuc auacacgaac cauccgcggc ccucuuagcu uacggaaucg      600

gacaagacuc ccccaccggc aagucaaaca uccuaguauu caaacuagga ggaaccucac      660

uaucacucuc agucauggag guaaacucag gcaucuaccg cguccucagc accaacacag      720

acgacaacau cggaggagcc cacuucaccg aaacacucgc ccaguaccuc gccuccgagu      780

uccagcgauc guucaaacau gacguacgag gaaacgcacg cgcaaugaug aagcucacga      840

acagcgcaga agucgcaaag cacucccuaa gcacacuagg cagcgcaaac ugcuuccugg      900

acucauuaua cgaaggacag gacuucgacu gcaacguaag ccgcgccaga uucgaacucc      960

ucugcucacc ccucuucaac aaaugcaucg aagccauacg cggacuacua gaccaaaacg     1020

gguucaccgc cgacgacauc aacaaagucg uucucugcgg cggauccagc cgcaucccca     1080

aacugcaaca acucaucaag gaccuauucc ccgccgucga gcugcuaaac uccauaccac     1140

ccgacgaagu uauacccauu ggagcagcaa uagaggccgg cauccucauc ggcaaagaga     1200

accuccucgu cgaagacucc cugaugaucg agugcuccgc cagagacaua cucgucaaag     1260

gcgucgacga aucaggagca ucacgcuuca caguccuauu ccccucugga acaccccuuc     1320

cagcacgacg acaacacacc cuacaagcac caggcagcau uuccuccguc ugccuagaac     1380

ucuacgaauc cgauggcaaa aacucggcca aagaagaaac caaguucgca caagucguac     1440

uccaagaccu cgacaagaaa gaaaacggac uccgcgacau ccuggccgug cucaccauga     1500

agcgagaugg aucacuacac gugaccugca ccgaccagga aaccggcaaa ugcgaagcca     1560

ucagcaucga aaucgcaucc uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  3396
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt8)

<400>  3396
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccg       60

ucgucggacu ggacguggga agccaaagcu gcuacauagc agucgcccgg gcagggggca      120

ucgaaacaau cgccaaugag uucagcgaca gaugcacucc aagcgucauc uccuucggau      180

ccaaaaacag aacaauagga gucgccgcca aaaaccaaca gauaacccac gcaaacaaca      240

ccgucucaaa cuucaaacgg uuccacggca gagcauucaa cgaccccuuc auacaaaaag      300

aaaaagaaaa ccuaucauac gaccucgucc cacucaaaaa cggaggaguc gguaucaaag      360

ucauguacau gggcgaagaa caccuuuucu caguagagca aauaacagca augcuacuaa      420

ccaaacucaa agagacagca gaaaacucgc ugaagaaacc agucacagau ugcgucauaa      480

gcgucccgag cuucuucacc gacgccgaac gacgcucagu acuagacgca gcccaaaucg      540

ucggccugaa cugucucaga cuaaugaacg auaugacggc agucgcccua aacuacggca      600

uauacaaaca ggaccuccca ucacuggaug aaaaaccacg uaucgugguc uucgucgaca      660

ugggccacuc agcauuccaa gucuccgcau gcgccuucaa caaaggcaaa cucaaaguac      720

uaggcacagc cuucgaccca uuccuugggg gcaaaaacuu cgacgaaaaa cuggucgagc      780

acuuuugcgc agaguucaaa accaaauaca aacucgacgc caaaagcaaa auccgagcac      840

uucuacgauu auaccaagaa ugcgaaaaac ucaagaaacu caugagcagc aacucgacag      900

accuccccuu gaacaucgaa ugcuucauga augacaagga cgugucaggg aagaugaacc      960

ggucacaguu cgaagaacug ugcgccgaac uccugcagaa aaucgaaguc ccacuguacu     1020

cccuacucga acaaacccac cugaaagucg aagacgucuc agcaguagaa aucgugggag     1080

gggcaacccg aauaccugcc gucaaagaac guaucgcgaa auucuucgga aaagacauca     1140

guacaacgcu caacgccgac gaagcagucg ccagagggug cgcacuccaa ugcgcgaucc     1200

uaucccccgc guucaaagua cgcgaguucu ccgugacuga cgccguccca uucccaaucu     1260

cacuaaucug gaaccacgac ucagaagaca cggaaggagu ccacgaaguc uucagccgca     1320

accacgcugc ccccuucucu aaaguauuaa ccuuccuccg ccgaggucca uucgaacucg     1380

aagcguucua cucagaccca caagggguac ccuacccgga ggcgaaaauc ggccgcuuug     1440

uaguacaaaa cgucucagcc cagaaagacg gcgaaaaauc ccgggucaaa gucaaagucc     1500

gcgucaacac ccacggcaua uucaccaucu caacugccag cauggucgag aaaguaccaa     1560

cagaggagaa cgaaauguca agcgaagccg acauggaaug ccuaaaucaa agaccgccag     1620

aaaacccuga caccgacaaa aacguacaac aagacaauuc cgaagcaggg acccagccac     1680

aaguccagac agacgcacaa cagaccagcc aaucaccccc auccccagag cucacgagcg     1740

aagaaaacaa aauaccagac gcagacaagg caaacgaaaa gaaagucgac cagccgccag     1800

aagcgaaaaa gccgaaaauc aaaguaguca acgucgaacu ccccauagaa gcaaaccucg     1860

uauggcagcu cgggaaagac cuccuaaaca uguacaucga gacagaaggc aaaaugauaa     1920

ugcaagacaa acuagaaaaa gaaagaaacg acgcuaaaaa cgcaguagaa gaguacgucu     1980

acgaguuccg cgacaaacuc ugugggcccu acgaaaaauu caucugcgaa caagaccacc     2040

aaaacuuccu aagacuccua accgaaacgg aagacuggcu cuacgaagaa ggcgaggacc     2100

aagcaaaaca agccuacguc gauaaacucg aggagcuaau gaaaaucggc acgcccguca     2160

aaguccgcuu ccaagaagca gaagaacgac cgaagauguu cgaagaacug ggccagcgcu     2220

ugcaacacua cgcgaaaaua gcggccgacu uccgcaacaa agacgaaaaa uauaaccaca     2280

uagacgaauc agagaugaaa aagguagaga aaagcguaaa cgaaguaaug gaauggauga     2340

acaacgucau gaacgcccaa gccaagaaau cacuagacca agaccccguu gucagagccc     2400

aagaaauaaa aaccaaaauu aaagaacuca acaacacaug cgagccaguc gucacccaac     2460

cgaaaccaaa aauagaaucu ccaaaacucg aaagaacccc aaacggcccu aacaucgaua     2520

agaaagaaga ggaucucgaa gacaaaaaca acuucggggc agaacccccg caccaaaacg     2580

gcgaaugcua ccccaacgag aaaaacucug ugaacaugga ccuagauuaa ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  3397
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt8)

<400>  3397
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaaguccg acgacaacga ccgcgccgac gaguauguug ggcgcucguc gccguacugc      120

ucgccgaccu acuggcccua agugacaccc ucgcagugau gaguguagac cuaggcuccg      180

aauccaugaa ggucgcgaua gucaaaccag gagugccgau ggaaauaguc cucaacaagg      240

aauccaggcg aaaaacccca guaauaguaa cccucaaaga aaacgagcgg uucuuuggag      300

acucagcagc aagcauggca aucaagaauc caaaagccac ccuacgauac uuccaacacc      360

uacuaggaaa gcaggcagac aacccacacg ucgcacuaua ccaggccagg uucccggaac      420

acgagcugac cuucgacccc caaaggcaaa cgguacacuu ccaaaucagc agccaacuac      480

aauucagccc agaagaaguc cucggaaugg uccuaaacua cagcagaagc cucgcagagg      540

auuucgccga acagccaaua aaagacgccg uaauaacagu cccaguauuc uucaaccaag      600

ccgagcgacg agccguccua caggcagcac gcauggccgg gcucaaggua cuccagcuaa      660

uaaacgacaa cacggcaacg gcccuauccu acggagucuu ucggagaaaa gacauaaaca      720

caaccgcaca aaacauaaug uucuacgaca ugggcucagg cucgacaguc ugcacaauag      780

ucacauacca gauggucaaa acaaaggaag ccgggaugca accgcaacug caaauacgag      840

gagucggauu cgaccgaaca cugggaggac uagaaaugga acuacgacuc cgagagaggc      900

uggccggccu auucaacgaa caaagaaaag gccaacgcgc aaaagacgua agggaaaacc      960

cacgagcaau ggcuaaacua cuccgagaag ccaaccgacu gaaaacagua cuaagcgcaa     1020

acgcagacca cauggcgcaa auugaagggc uaauggacga cguagacuuc aaagcaaaag     1080

ucacccgcgu ggaguucgag gaacucugcg cagaccuguu ugaacgcguc cccggccccg     1140

uacaacaagc acugcaaagc gcagaaauga gccuagacga gauagaacaa guaauccuag     1200

uaggcggcgc cacacgagua cccagaguuc aagagguacu acugaaagcu gucgggaaag     1260

aggaacuagg caaaaacauc aacgccgacg aggccgcagc aaugggagcc guauaucaag     1320

cagcagcauu aaguaaagca uucaagguaa agccguuugu aguacgggac gccgucguau     1380

acccaauuuu agucgaguuc acgcgggaag ucgaagagga acccggaaua cacucacuga     1440

aacacaacaa acgcguccua uucucacgaa ugggucccua cccacaaaga aaaguaauaa     1500

ccuucaaccg auacagccac gacuucaauu uccacaucaa cuacggcgac cuuggauucc     1560

uagggcccga agaccugaga gucuucggaa gccagaaccu caccacaguc aaacugaaag     1620

gaguggggga cagcuucaag aaauacccag acuaugaauc aaaaggaaua aaggcacacu     1680

ucaaccucga ugaaagcgga guacugagcc uggacagggu agaaagcguu uucgagacac     1740

ugguggaaga cagugccgaa gaagagagca cacuaacaaa acugggcaac acaaucagua     1800

gccucuucgg gggcggaaca acgccagacg caaaagaaaa cgggaccgac accguacaag     1860

aagaagaaga aagcccagcc gaaggaagca aggacgagcc aggagagcag guagagcuca     1920

aagaagaagc agaggcgccc guagaagacg gcucucagcc accuccgccc gaacccaaag     1980

gagacgcaac accagaggga gagaaggcga ccgaaaaaga aaacggcgac aaaagcgagg     2040

cgcaaaaacc gucggagaaa gccgaggcgg gaccagaagg aguagcccca gcacccgaag     2100

gcgaaaagaa acaaaaacca gcgagaaaaa gaaggauggu ggaggaaauc ggcguggaac     2160

ugguagugcu agauuuaccc gaccucccag aagacaaacu cgcgcagucg guacagaaau     2220

uacaagaccu gacacuaaga gaucuugaaa aacaagaacg agagaaggcg gcaaacaguc     2280

uggaagcguu caucuucgag acgcaggaca aacuauacca gccggaguac caagagguau     2340

caaccgaaga acaaagagag gaaaucuccg gcaagcuauc ggcggccuca acauggcucg     2400

aggaugaagg gguaggcgcc accacaguga ugcuaaaaga aaagcuagcu gaacuaagaa     2460

aacuaugcca aggucuauuu uuccgagucg aggaaaggaa gaaauggcca gaaagacuau     2520

cggcccucga caaccuacua aaccacucca gcauguuucu aaaaggcgcg agacuaauac     2580

cagagaugga ccaaaucuuc acggaagucg aaaugaccac acuagaaaaa gugauaaacg     2640

agacgugggc auggaaaaau gccacacucg cagaacaagc caaacuaccc gcaacggaaa     2700

agcccguccu acucagcaaa gacaucgaag caaaaaugau ggcguuagac cgcgaaguac     2760

aguaccuacu aaacaaagcg aaauucacca aaccacgacc ccgccccaaa gacaaaaacg     2820

gcacacgggc agagccacca cugaacgcaa gcgccucaga ccaaggggaa aaggucauac     2880

ccccggccgg acaaaccgaa gacgcggaac caauaagcga gcccgaaaag guggagacgg     2940

gaagcgaacc cggcgacaca gagccacugg aacuaggagg cccgggcgca gaaccagagc     3000

aaaaggaaca aagcacaggg caaaagaggc cacucaaaaa cgaugaacua uaaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3398
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt8)

<400>  3398
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

aagaaacgca aacgcaagac caaccaaugg aagaggagga aguagaaacg uucgccuucc      120

aggcagagau cgcccaacua augagccuga uaauaaacac auucuacucg aacaaagaga      180

uauuccucag agagcucaua agcaacagcu cggacgcacu ggacaaaaua cgauacgaau      240

cccuaaccga cccgagcaaa cucgacuccg gcaaagaacu ccacaucaac cuaauaccaa      300

auaaacagga ccggacacuc accaucgucg acacagggau aggaaugaca aaagcggacc      360

ugaucaacaa ccuaggaacg auugcaaaaa gcggaacaaa agcguucaug gaagcccucc      420

aagcaggcgc cgauauaucc augauaggac aauucggcgu gggguucuac ucagcauacu      480

uagucgcgga aaaagucacg guaauaacga aacacaacga cgacgaacag uacgcguggg      540

agagcuccgc aggcggcagc uucacaguua ggacagacac cggagagccc auggggcgag      600

ggaccaaggu cauccuucac cucaaagaag accaaacgga auaccucgaa gaaaggcgca      660

uaaaggaaau cgugaagaaa cacucccaau ucauaggaua cccuaucaca cuauucguag      720

aaaaagaacg cgacaaagag guaagcgacg acgaagcgga agagaaggaa gacaaggaag      780

aggaaaaaga gaaggaagag aaagaaagcg aagacaagcc cgaaauagaa gacguaggcu      840

cggacgagga agaagaaaag aaagacggcg acaaaaagaa gaaaaagaaa auaaaagaaa      900

aauacauuga ccaggaggaa cucaacaaaa cgaaaccgau auggaccagg aacccggacg      960

acaucacaaa cgaagaauac ggggaguucu acaaaucgcu cacaaacgac ugggaagacc     1020

accuagcggu caaacacuuc aguguggagg gacaacuaga guucagagca cuccuguucg     1080

ucccaaggcg agccccauuc gaccuauucg aaaaccgcaa aaagaaaaac aacauaaaac     1140

ucuacgucag aagagucuuu auaauggaca acugcgagga acuaaucccc gaauaccuaa     1200

auuucauccg aggggucgug gacucugaag accucccacu aaacaucuca agagaaaugc     1260

ugcagcaaag uaagauccua aaagugaucc gcaaaaaccu aguaaagaaa ugccuggaac     1320

uguucacgga acuggcggag gauaaagaaa acuacaaaaa guucuacgaa caauucucca     1380

agaacauuaa acuggggauc cacgaagacu cccaaaacag aaagaaacug agcgaacucc     1440

ugcgauacua caccagcgcg uccggagacg agauggucag ccuaaaggac uacugcacca     1500

gaaugaaaga aaaccaaaaa cacaucuacu auauaacagg ggaaaccaag gaccaagucg     1560

caaacagcgc cuuuguagag cgccugagaa aacacggacu cgaagucaua uacaugauag     1620

aaccaaucga cgaauacugc guacagcagc ugaaggaguu cgaaggaaaa acgcuaguau     1680

cgguaacgaa agagggacua gagcuacccg aagacgagga agagaaaaag aaacaagaag     1740

aaaagaaaac caaauucgag aaccucugca aaauaaugaa agacauccua gaaaagaaag     1800

uagaaaaagu cguaguguca aaccgccucg ucacgagccc auguugcaua gucacgucaa     1860

ccuacggaug gacagccaac auggagagga uaaugaaagc ccaagcccua cgagacaacu     1920

caacaauggg auacauggcc gccaagaaac accuagaaau aaaccccgac cauucgauaa     1980

uagagacucu ccgacaaaaa gccgaggccg acaagaacga caagagcgua aaagaccugg     2040

uaauccuccu cuacgaaacg gcccuccuau caagcggguu cagccuagaa gacccacaaa     2100

cccacgccaa ccgcaucuac agaaugauaa aacuaggacu cggaaucgac gaagacgacc     2160

cgaccgcgga cgacaccuca gcagcgguaa cagaggaaau gcccccacua gaaggggacg     2220

acgacacgag cagaauggag gaaguagacu aaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  3399
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt8)

<400>  3399
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

ccucaaaacu agacuccggc aaaggacucc acaucaaccu cguccccaac aaacaaaacc      120

aaacacucac cauaguagac acacgcaucg gcaugaccaa aacagaccuc aucaacaacc      180

ucggcaccgu caccaaaucc ggaacaaaag ccuucaugga agcacuccaa gccgacgcag      240

acaucuccau gaucggacac uucggcgucg gcuucuacuc agcauaccuc gucgccaaaa      300

aagucaccgu aaucucaaaa cacaacaacg acgaacaaua caccugggaa uccuccgcag      360

gcggcuccuu caccguacga acagacgaau aaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  3400
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt8)

<400>  3400
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aagagguaca ccauggugaa gaggaagucg agaccuucgc cuuccaagcc gaaauagcac      120

aauuaaugag ccugauaauc aacaccuucu acucgaacaa agaaaucuuc cugcgcgaac      180

ucaucucgaa cgcaagcgac gcccuagaca agauaagaua cgaaucacug acagacccca      240

gcaagcuaga cucagggaag gagcucaaaa ucgacaucau uccaaacccc caagaacgga      300

cacuaacccu gguggacaca gggaucggga ugaccaaggc cgaccugaua aacaaccucg      360

ggacaaucgc caaaagcggc accaaagcgu uuauggaggc ccuacaagcc ggagccgaca      420

ucagcaugau cgggcaauuc ggcgucggau ucuacagcgc cuaucuagua gcggaaaaag      480

uaguagugau cacaaaacac aacgacgacg aacaauacgc cugggaaagc agugcaggag      540

gcagcuucac ggugcgagcc gaucacggag aacccauagg acggggcacc aaggugauac      600

ugcaccucaa agaagaccaa accgaauacc uggaagaacg acgaguaaag gaggucguaa      660

agaagcacag ccaauucaua ggcuacccaa uaaccuugua ccuagagaaa gaacgggaaa      720

aagagauaag ugacgacgaa gcugaagaag aaaaaggcga aaaagaagaa gaagacaaag      780

acgacgaaga aaagcccaaa aucgaggacg uaggcagcga cgaagaagac gacagcggaa      840

aagacaagaa aaagaaaaca aagaaaauaa aagagaagua caucgaccaa gaagaacuca      900

acaaaacgaa gcccauaugg acaagaaauc cagacgauau cacgcaagaa gaauacggag      960

aguucuauaa gagucuaacc aacgacuggg aagaccaccu agcggucaaa cacuucagcg     1020

ucgaaggaca gcuagaguuc cgagcccugc uauucauccc ccgaagggca cccuucgacc     1080

uauuugaaaa caaaaagaag aaaaacaaca uuaaacucua cguacgccgc gucuucauaa     1140

uggacagcug cgacgaacua auaccagaau accugaacuu cauccgcgga gucgucgaca     1200

gcgaagaccu accacugaac auaucacgag aaaugcugca acaaagcaaa auccucaaag     1260

ucauacgcaa aaacaucgua aagaaaugcc uugaacuauu uucggaacug gcagaagaca     1320

aagaaaauua caagaaauuc uacgaagccu ucagcaaaaa ccucaaacug ggaauccacg     1380

aagacuccac aaaccgaaga agacuaagcg aacuccuaag auaccacacc agucaaagcg     1440

gcgacgaaau gacaagccuc ucagaauacg ugucccgaau gaaagaaacc cagaaaagca     1500

ucuacuacau cacgggcgaa agcaaagaac aaguagcaaa cagugcuuuc guagaacggg     1560

ugagaaagcg aggauucgaa gucguguaua ugaccgaacc aaucgacgaa uacugcguac     1620

aacaacuaaa agaguucgau ggcaaguccc ucguaucagu cacgaaagaa ggccuagaac     1680

ugccggaaga cgaagaagag aaaaagaaaa uggaagaaag caaagcaaaa uucgaaaacc     1740

ugugcaaacu caugaaagaa auacucgaca agaaagucga aaaaguaaca auaagcaacc     1800

ggcuagugag cagcccaugc ugcaucguca caagcacaua cggcuggacg gcgaacaugg     1860

aaagaauaau gaaagcacaa gcccuacgag acaacagcac gaugggauac augauggcaa     1920

agaagcaccu agaaaucaac ccagaccacc caaucgugga aacacuccga caaaaagccg     1980

aagcagacaa gaacgacaag gccguaaaag aucuaguggu acuacuguuc gaaaccgcgc     2040

uacucagcuc aggauucagc cucgaggacc cacaaaccca cucgaacagg aucuacagaa     2100

ugaucaaacu aggccuggga auagacgaag acgaagucgc cgccgaagaa cccaacgcgg     2160

cagucccaga cgaaauccca ccauuggagg gagacgaaga cgcaagcagg auggaggaag     2220

uagacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  3401
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt8)

<400>  3401
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaggg       60

cguuaugggu ccuagggcug ugcugcgucc uccugacguu cggcagcguc agagcagacg      120

acgaagugga cguagacggc accguagaag aagaccuggg aaaauccaga gaggguagca      180

gaaccgacga ugaagucgug cagcgagagg aagaagccau ccaacucgac gggcugaacg      240

cgucacagau acgggaacua cgagagaaaa gcgaaaaauu cgccuuccaa gcagaaguca      300

accgaaugau gaaguuaauc auaaacucac uauacaaaaa uaaagaaaua uuccucagag      360

aacugauaag caacgcgagu gacgcacuag acaaaaucag acucaucagc cucaccgacg      420

aaaacgcccu uagugggaac gaagaacuaa cagucaaaau caaaugcgac aaggaaaaga      480

accuacuaca cguaacagac acggguguag gaaugacccg ggaggaacuc gucaaaaacc      540

ucggcaccau agcgaaaagc ggaacaucag aguuccucaa caaaaugaca gaggcccagg      600

aagacggaca aagcaccagc gaacugaucg ggcaauucgg aguaggauuc uacagcgcgu      660

uccucguggc agauaagguc aucgucaccu caaaacacaa caacgacacc cagcacauau      720

gggagagcga cagcaacgag uucuccguaa ucgcggaccc ccgcgggaac acgcucggcc      780

gcggaaccac aaucacacuc guacucaaag aagaagcaag cgacuaccua gagcucgaua      840

caauaaagaa ccuggugaaa aaguacagcc aguucaucaa cuucccaauc uacguaugga      900

gcagcaaaac ugagacggua gaagaaccaa uggaagaaga ggaagcagcc aaagaagaaa      960

aagaagaguc ggacgacgag gcagcgguag aagaagaaga agaagagaag aaaccgaaaa     1020

ccaagaaagu agagaaaacg guaugggauu gggaacuaau gaacgacauc aaacccauau     1080

ggcagcgccc cagcaaagaa gucgaagaag acgaauacaa ggcauucuac aagagcuuca     1140

gcaaagaaag ugacgacccg auggccuaca uacacuucac cgcagaaggg gaaguaacau     1200

ucaagagcau acuauucguc ccaaccucag cgccgcgagg acucuucgac gaguacggga     1260

gcaagaaaag cgacuacauc aaacuguacg uaagacgcgu auucauaacc gacgacuucc     1320

acgacaugau gcccaaauac cuaaacuuug ugaaaggggu aguagacagc gacgaccuac     1380

cccuaaacgu guccagagaa acccuccagc agcacaaacu ccugaaggua auaaggaaga     1440

aacuggugcg gaaaacacua gacaugauaa agaaaauagc cgacgacaag uacaacgaca     1500

ccuucuggaa ggaguucggc accaacauaa aacuaggggu gaucgaagac cauagcaacc     1560

ggacccgacu cgcaaaacuc cuaagauucc aaucaagcca ccaccccacc gacauaacga     1620

gccucgacca guacguggaa aggaugaagg aaaagcaaga uaaaaucuac uuuauggcgg     1680

gcuccucccg aaaagaagca gaaagcucac ccuucguaga gcgacuacuc aagaaagggu     1740

acgaaguuau auaccugaca gaaccugugg acgaauacug cauacaagca cugccggagu     1800

ucgauggcaa acgcuuccaa aacguggcaa aagaaggcgu aaaauucgac gaaagcgaga     1860

aaacgaaaga aucacgcgaa gcaguagaaa aagaguucga accccuacuc aauuggauga     1920

aagacaaagc auuaaaagac aaaauagaaa aagcaguagu gagccaacgc uugaccgaaa     1980

gcccgugugc ccucguagca agccaguacg gcuggagcgg gaacauggag agaaucauga     2040

aagcgcaggc guaccaaaca ggaaaagaca uauccaccaa cuacuacgcu ucacaaaaga     2100

aaaccuucga aauaaaccca agacauccgc uaauccgcga caugcugcga cgaauaaagg     2160

aggacgaaga cgacaagaca guacucgacc ucgcagucgu ccucuucgaa accgcaacgc     2220

uacggucagg cuaccugcuc ccagacacga aagcauacgg agacaggaua gagaggaugc     2280

ucagacuaag ccuaaacaua gacccggacg ccaagguaga agaagaacca gaggaagaac     2340

cggaagaaac ggcagaagac accacagagg acacagagca agacgaggac gaggaaaugg     2400

acguaggaac ugaugaagaa gaagaaacgg ccaaagaauc gacagcagaa aaggacgaac     2460

uauaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  3402
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt8)

<400>  3402
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

gagaacuaag ggcccuccuc cuuuggggcc gacgccuccg cccgcuacuu cgcgcgccag      120

cacuggcagc ugucccagga ggcaaaccca uccuaugccc ccgccgaaca accgcacagc      180

ucggucccag acgcaaccca gcuugguccc uucaagcagg ccgccucuuc uccacucaaa      240

cagcagaaga caaagaagaa ccacuccaca gcauaaucuc aucaaccgaa ucaguacaag      300

gcucaacauc uaaacacgag uuccaagccg aaacuaagaa acugcucgac auaguggcca      360

gaucccuaua cuccgaaaaa gaagucuuca uccgcgaauu gaucucaaac gcauccgacg      420

cacucgaaaa acuacgacac aaacucgucu ccgacggcca agcccuccca gaaauggaaa      480

uccaucugca aacuaacgcc gaaaaaggca ccauaacaau ccaggacaca ggcaucggca      540

ugacccaaga ggaacuuguc uccaaccucg gaacaaucgc ccgcagcgga uccaaagcau      600

uccucgacgc ccuacaaaac caagcagaag caagcuccaa aaucaucgga caauucggag      660

ucggcuucua cucagccuuc auggucgccg accgcgucga aguguacuca cgcucagcug      720

cacccggaag ucuaggcuau caauggcuau cagacggaag cggggucuuc gaaaucgcag      780

aagccucugg cgugcgcaca ggcaccaaaa ucaucaucca ccugaaaucc gacugcaaag      840

aguucucgag cgaagcacga gucagggacg uuguaaccaa auacucaaac uucguauccu      900

uuccacuaua ccucaauggc cgucgaauga acacccucca agcaaucugg augauggacc      960

cuaaagacgu aagagaaugg caacacgaag aguucuaccg cuacguugcc caagcucacg     1020

acaaaccacg uuacacccug cacuacaaaa ccgacgcacc ccugaauauc cgaagcauuu     1080

ucuacguccc cgacaugaaa cccucuaugu ucgacguauc ccgcgaacuc ggcuccucag     1140

ucgcccuaua cucccgcaaa guccuuauac aaaccaaagc caccgacaua cucccaaaau     1200

ggcuccgcuu uauacgagga gucgucgacu cagaagacau cccgcucaac cugagccgag     1260

aacuacucca agaauccgcc cucauucgca aacugcguga cguccuccaa caacgccuca     1320

ucaaauucuu caucgaccaa ucaaagaaag acgccgaaaa auacgcuaaa uucuucgaag     1380

acuacggccu auucaugcgc gaaggaaucg ugaccgccac agaacaagag gucaaagaag     1440

acauagccaa acuccuaaga uacgaauccu ccgcacugcc cucgggacaa uuaaccucac     1500

uauccgaaua cgcaagccgu augcgcgccg ggacccgcaa caucuacuac cucugcgccc     1560

ccaaccgaca ccuggcagag cacuccccau acuacgaggc aaugaaaaag aaagacaccg     1620

aaguccuuuu cugcuucgaa caauucgacg aacuaacccu cuuacaccua agggaguucg     1680

acaaaaagaa acucaucuca guggaaacgg acaucguagu cgaccacuac aaagaagaaa     1740

aauucgaaga ccgcucacca gccgcagaau gucuauccga aaaagaaaca gaagaacuca     1800

uggccuggau gcgcaacguc cuaggcaguc gcgucacaaa cgucaaagua acccuuagac     1860

uugacaccca ucccgccaug guaacagucc ucgaaauggg agccgcacgc cacuuccuaa     1920

gaaugcagca acuagccaaa acacaagaag aaagagccca acuccuacaa ccuacacuag     1980

aaaucaaccc ccgccacgca cucaucaaga aacuaaacca acuacgcgca agcgaaccag     2040

gccuagcgca acuccuagua gaccaaaucu acgaaaacgc caugauagca gcaggccuag     2100

uagacgaccc ccgcgccaug gucggccgcc ucaacgaacu ccuaguaaaa gcccucgaaa     2160

gacacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  3403
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt8)

<400>  3403
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

aaaucuccuc acuccccaca caacuauuca aaugcugcuu cugcgacuuc cucaaaguca      120

aaaugcacac aauguccucc ucacaccucu ucuaccuagc ccucugccua cucaccuuca      180

caucaucagc cacagccggc ccugaaaccu uaugcggagc cgaacucgua gacgcccucc      240

aauucgucug cggagaccga ggcuucuacu ucaacaaacc caccgguuac ggaucaucau      300

cccgccgcgc cccacaaaca ggcaucgucg acgaaugcug cuuccgcuca ugcgaccucc      360

gaagacuaga aauguacugc gcaccccuca aacccgccaa auccgcccgc uccguccgag      420

cccaacgcca cacagacaug cccaaaacac aaaaagaagu ccaccucaaa aacgccuccc      480

gaggauccgc cggcaacaaa aacuaccgca uguaaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  3404
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt8)

<400>  3404
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

uaccaauggg caaauccaug cuaguacucc uaaccuuccu ugccuucgca uccugcugca      120

uagccgccua ccgacccucc gaaacacucu gcggcggcga auuagucgac acccuacaau      180

ucgucugcgg cgaccgcggc uucuacuucu cccgaccagc cucccgcguc uccagacgcu      240

cacgcggcau cguagaagaa ugcugcuucc gaucaugcga ccucgcccuc cucgaaaccu      300

acugcgccac ccccgcaaaa ucagaacgag acgucucaac cccacccacc guccuccccg      360

acaacuuccc cagauacccc guaggcaaau ucuuccaaua cgacaccugg aaacaaucca      420

cccaaagacu uagacgcggc cuccccgccc uacuccgagc ccgccgcgga cacguacucg      480

ccaaagaacu cgaagccuuc cgcgaagcca aacgccaccg cccacucauc gcccuaccca      540

cacaagaccc cgcccacggc ggcgcacccc cagaaauggc cucaaaccga aaauaaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  3405
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt8)

<400>  3405
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

ccuucuccac aucagccuuc ggccccgucg ccuucucccu cggacuccuc cuuguccucc      120

cagccgccuu ccccgcccca gucccccccg gcgaagacuc aaaagacgua gccgcccccc      180

accgacaacc ccuuaccucc uccgaacgca ucgacaaaca aauacgauac auccuagacg      240

gcaucucagc ccuccgcaaa gaaaccugca acaaauccaa caugugcgaa ucuuccaaag      300

aagcccuagc cgaaaacaac cucaaccucc ccaaaauggc cgaaaaagac ggcugcuucc      360

aaucaggauu caacgaagaa accugccuug ucaaaaucau caccggccuc cucgaauucg      420

aagucuaccu cgaauaccuc caaaaccgcu ucgaaucauc cgaagaacaa gcccgcgccg      480

uccaaauguc aacaaaaguc cucauacaau uccuccaaaa aaaagccaaa aaccucgacg      540

ccauaaccac ccccgacccc accaccaacg ccucacuacu aaccaaacuc caagcccaaa      600

accaauggcu acaagacaug accacccacc ucauccuccg cuccuucaaa gaauuccuac      660

aaagcucccu ccgcgcccua cgccaaaugu aaggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  3406
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt8)

<400>  3406
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uacuauggcu ccgcggcuuc cuacuggccu caugcuggau caucguacgc agcagcccca      120

caccaggaag cgagggacac agcgcagccc cagacugccc aagcugcgcc cuagcggccc      180

ugccaaaaga cguacccaac agccaacccg aaaugguaga agccgucaaa aaacacauac      240

uaaacaugcu acaccuaaaa aaaaggccag acguaacaca acccguccca aaagcagcac      300

uacucaacgc aauccgcaaa cuccacgucg ggaaagucgg agaaaacgga uacguagaga      360

uagaagacga caucgggcgc cgcgccgaaa ugaacgaacu cauggaacaa accucagaga      420

uaaucacguu cgccgaaagc ggaacagccc gcaaaacacu acacuucgaa auaagcaaag      480

aaggcagcga ccuaagcguc gucgagcgcg cagaagucug gcucuuccuc aaaguaccca      540

aagcaaaccg cacacgaaca aaagucacaa uacgacuguu ccagcaacaa aagcacccac      600

aaggcucccu cgacacaggc gaagaagcag aagaaguagg ccuaaaagga gaacggagcg      660

aacuacuccu aucagaaaaa gucguagacg cacgcaaaag cacguggcac gucuucccag      720

uaagcagcag cauacaacga cuacucgacc aaggcaaaag cagccucgac gucagaauag      780

caugcgaaca augccaagaa ucaggcgccu cccucguccu acugggaaaa aaaaagaaaa      840

aagaagaaga aggcgaagga aagaaaaaag gcgguggaga aggaggcgca ggagcggacg      900

aggaaaaaga acaaucccac cgcccauuuc uaaugcugca agcacggcaa ucagaagacc      960

acccccaccg ccgccgacga cgaggacuag aaugcgacgg aaaagucaac aucugcugca     1020

aaaaacaauu cuucgucagc uucaaagaca uaggauggaa cgacuggaua auagcgccaa     1080

gcggauacca cgcaaacuac ugcgaaggcg aaugccccag ccacauagca ggcacaagcg     1140

ggagcagccu gucguuccac agcaccguga ucaaccacua cagaaugaga ggacacuccc     1200

cauucgcaaa ccugaaaucg ugcugcgucc ccaccaaacu acgaccgaug agcaugcucu     1260

acuacgacga cggacagaac aucauaaaaa aagacauaca aaauaugauc guggaagagu     1320

gcggaugcag cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  3407
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt8)

<400>  3407
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacg       60

gccugccagg ccgagcguua ggcgccgccu gccuccuacu ccuagcagca ggcuggcucg      120

gccccgaagc cuggggauca ccaaccccac caccaacccc cgcagccccu cccccacccc      180

caccacccgg cagucccggc ggaucacaag auaccugcac cucaugcggc ggauuccgca      240

gaccagaaga acucggacgc guagacggag acuuccucga agccguaaaa agacacauac      300

uaucccgccu ccaaaugcgc ggccgaccca acaucacaca cgccgucccc aaagccgcca      360

uggucaccgc ccuacgcaaa cuacacgccg gcaaaguucg cgaggacggc cgagucgaaa      420

ucccacaccu cgacggccac gccucccccg gcgcagacgg acaagaacga guuagcgaaa      480

ucaucuccuu ugccgaaaca gacggccuag ccucaucacg aguccgacuc uacuuuuuca      540

ucuccaacga aggaaaccaa aaccucuucg ucguacaagc aucccuaugg cuauaccuaa      600

aacuccuacc cuacgucuua gaaaaaggau cccgccgcaa aguccgcguc aaagucuacu      660

uccaagaaca gggccacggc gaccgcugga acauggucga aaaacgcgua gaccucaaac      720

gcuccggcug gcacaccuuc ccccuaaccg aagccaucca agcccucuuc gaacgcggcg      780

aacgacgccu aaaccucgac guacagugcg acucaugcca agaacucgcc guaguacccg      840

uauucgucga cccaggggaa gaaagccaca gaccauucgu cgucguccaa gccagacucg      900

gcgacucccg acaccgcaua cgcaaacgag gccucgaaug cgacggccgc acaaaccucu      960

guugccgcca acaauucuuc aucgacuucc gccuaaucgg uuggaacgac uggauuauag     1020

ccccaacagg auacuacggc aacuacugcg aagggucaug ccccgccuac cuagccggag     1080

uccccggcuc ugccagcuca uuccacacag cagucgugaa ccaauaccgc augcgaggcc     1140

uaaaccccgg caccguaaac ucuugcugca uccccacaaa auuaucaacc auguccaugc     1200

uuuacuucga cgacgaauac aacauaguca aacgcgacgu ccccaacaug auaguagaag     1260

aaugcggcug cgccuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  3408
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt8)

<400>  3408
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

uucgcguccu ccuccuuacc gcccuaaccc uaugucaugg auucaaccuc gacaccgaaa      120

augccaugac cuuucaagaa aacgcccgcg gauucggcca gucuguagua cagcuccaag      180

gaucuagagu agucgucggu gccccucaag aaaucguagc agcaaaccaa cgcgguaguc      240

uauaccaaug ugacuacucu acuggcucgu gcgaaccuau caggcuccaa guccccgugg      300

aagccgucaa cauguccuua ggacuaucac uggccgccac caccucccca ccgcaacucc      360

uagccugcgg acccaccgua caccaaacau guagcgaaaa cacguacguc aaaggacucu      420

guuuucucuu cggcagcaac cuacgccaac aaccccaaaa auucccugaa gcccucagag      480

gcugcccaca agaagacucc gacauagccu uccucaucga cggauccggc uccauuauac      540

cccacgacuu ccggaggaug aaagaauuug ucucgacggu aauggagcaa cucaagaaau      600

caaaaacacu guucagccua augcaauacu cggaggaguu ccgaauccac uucaccuuca      660

aagaguucca aaacaacccc aacccccgua gccuuguuaa acccauaacc caacuacugg      720

gccgaacaca caccgccacc ggcauccgca aagucguccg cgaacuauuc aacauaacca      780

acggcgcacg caaaaaugcu uucaagauac uuguaguaau cacagacgga gaaaaauucg      840

gagacccauu gggauacgaa gacgucauuc cugaagccga ccgagaaggc guaaucagau      900

acgugauagg uguaggcgac gcauucagau cagaaaaauc acgccaagaa cuaaacacaa      960

uagccuccaa gccaccccga gaccaugucu uccagguaaa caauuucgag gcacuuaaaa     1020

cuauucagaa ccagcuccgu gagaaaaucu ucgccaucga aggaacucag acaggauccu     1080

ccucgucuuu cgaacaugag augagccaag aaggcuucag cgcugccauc accucuaacg     1140

gacccuugcu aucuacaguc ggcuccuacg acugggccgg cggcguguuc cucuacaccu     1200

ccaaagaaaa auccacguuc auaaacauga cacgagucga cucggacaug aaugacgcgu     1260

accuugguua ugcugccgca auuauacuua gaaaccgugu gcaaucccuu guacucggcg     1320

cucccagaua ucaacacauc ggccucgucg cuauguuucg ucaaaauacc gggauguggg     1380

aauccaacgc caaugucaaa ggcacccaaa ucggcgccua cuucggcgcg agccuaugcu     1440

cagucgacgu cgacucaaac ggauccaccg aucuaguccu gaucggagca ccacacuauu     1500

acgaacaaac cagaggcggc cagguaucag ucugcccacu cccccgaggc cgcgcccgcu     1560

ggcaaugcga cgccguccuu uacggcgagc agggccagcc uuggggacga uucggagccg     1620

cccucaccgu acucggugac guuaacggag auaaacuaac agacgucgca aucggcgccc     1680

ccggagaaga agacaacaga ggagcggucu accucuuuca cggaaccucc gggagcggaa     1740

ucagcccguc ccauucccag cgcauugcag guagcaaacu caguccccgc cuccaguacu     1800

ucggccaauc ccuguccggc ggccaagacc uuacaaugga cggccuagua gaccucaccg     1860

ucggugcuca gggccauguc cugcuucuac gcucucaacc agucuuacga guaaaagcaa     1920

uaauggaguu caacccacgc gaagucgccc gcaacgucuu cgaaugcaac gaccaggucg     1980

uaaaaggcaa agaagccgga gaaguccgug uaugccugca cguacaaaag uccacccgcg     2040

accgccuacg ggaaggccaa auacagucug ucgucacuua ugaccucgcu cucgacuccg     2100

gaagaccgca cucucgggcc gucuuuaacg aaaccaaaaa cucaacacga cgacaaacac     2160

aggugcucgg ccugacgcag acaugcgaga cgcucaaauu gcagcuacca aacugcaucg     2220

aagacccagu aagcccuauu guccuucgcc uaaacuucag ccucgugggg acaccacuaa     2280

gcgccuucgg caaccuacgc ccgguacucg cggaagacgc ccagcgccuc uucaccgccc     2340

uuuuucccuu cgagaaaaac ugcggcaacg auaacaucug ccaagacgau cugucgauca     2400

ccuucagcuu caugucccuc gacugucucg uagucggagg cccccgugag uucaacguaa     2460

ccguaaccgu ccgcaacgac ggagaagaca gcuaccgcac ucaggucacc uuuuucuucc     2520

cccucgaccu gucuuacaga aaaguaucaa cacuccaaaa ccaacgaucc caacguucau     2580

ggcgacuagc cugcgaaucc gccagcucca cugaagucag cggcgcccuc aaaagcacgu     2640

ccugcucgau caaccacccc auauuccccg agaacucaga agucacauuc aacaucacau     2700

ucgacguaga uucaaaggcu ucacucggaa auaaacugcu ucucaaagcc aacgucaccu     2760

cagaaaauaa uaugccccgu acuaacaaaa ccgaguuuca acuagaacuc ccggucaaau     2820

acgccgucua caugguagua accucucacg gaguauccac caaguaccuc aacuucacug     2880

cauccgaaaa cacuucucgc gucaugcagc accaauauca agucuccaac cucggucaac     2940

guucacugcc caucucccua guauuccugg ucccaguacg ccuaaaccag accgucauau     3000

gggacagacc ccaagucacc uucucagaaa accuuagcuc uaccugccau acaaaggaaa     3060

gauuacccuc acacuccgac uuucucgcag agcucaggaa agcccccgua gucaacugcu     3120

cgauagcagu augccaacga auacaaugcg auaucccauu cuuuggcauc caggaagagu     3180

ucaacgccac ccugaagggu aaccucucau ucgacuggua cauaaagaca ucacauaacc     3240

aucuacuuau agucagcaca gccgaaaucc uguucaacga cucaguguuc acccuccugc     3300

ccggccaagg agccuucgua cgcucacaaa ccgaaacaaa aguugaaccu uucgaaguuc     3360

ccaacccccu uccgcucaua gucggcuccu cagucggagg ccuccuccua cucgcccuaa     3420

uaaccgcagc cuuguacaaa cucggauucu ucaaacgcca guacaaagac augaugucag     3480

aaggaggucc ucccggcgca gaaccacaau agggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  3409
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt8)

<400>  3409
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguucu       60

cacuaaaaac ccuacccuuu cuccuacucc uucacgucca gauaucaaaa gccuuccccg      120

ucuccucuaa agagaaaaac accaaaaccg ugcaagacua ccucgaaaaa uucuaccaac      180

ucccguccaa ccaauaccaa ucaacacgca aaaacggcac uaacguaauc gucgaaaaau      240

ugaaagaaau gcaacgauuc uucggccuca acgucaccgg caaacccaac gaagaaaccc      300

ucgacaugau gaagaaaccc cgaugcggag uacccgacuc uggcggcuuc augcucacuc      360

ccggcaaucc caaaugggaa cgcacuaacc ucaccuaccg caucagaaau uacacacccc      420

aacucucaga agccgaaguc gaaagagcga uuaaagacgc auucgaacua ugguccgucg      480

ccagcccccu aaucuucacc cgcaucuccc aaggugaagc cgacaucaac auagcauucu      540

accaacgcga ccacggugac aacuccccau ucgacggccc aaacggcaua cuugcccacg      600

cauuccaacc cggucaagga aucggaggcg acgcccacuu cgacgccgaa gaaaccugga      660

ccaacacauc cgcaaacuac aaccuauucc ucguugccgc ccacgaguuc ggccacuccc      720

uaggcuuagc acacuccucc gauccaggug cccuaaugua uccaaacuac gccuuccgcg      780

aaaccuccaa uuacucccua ccccaagaug acaucgacgg aauccaagca aucuacggac      840

ucucauccaa ccccauccaa cccaccgguc caucaacccc aaaacccugc gaccccuccc      900

ucaccuucga cgcaaucacc acucucagag gugaaauccu cuucuucaaa gaccguuacu      960

ucuggcgaag acacccacaa cuccaacgcg ucgaaaugaa cuuuauuuca cucuucuggc     1020

ccucgcuucc caccggcauc caggccgcau acgaagacuu cgaccgcgac cuaaucuucc     1080

ucuucaaagg uaaccaauac ugggcacuau caggcuacga cauccuucaa ggcuacccca     1140

aagacauauc caacuacggc uucccauccu ccguccaggc aaucgacgcu gcagucuucu     1200

auagauccaa aaccuacuuc uucgucaacg accaauucug gcgauacgac aaccaacgac     1260

aauucaugga acccggcuac cccaaaucaa ucuccggcgc uuuccccggc aucgaaucca     1320

aagucgacgc cguuuuccaa caagaacacu ucuuccacgu cuucuccggg ccacgauacu     1380

acgccuucga ccucaucgcc caacgcguca cccgaguagc acgcggcaac aaauggcuua     1440

acugccguua cggcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  3410
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt8)

<400>  3410
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccc       60

ucuggcaacc ccuaguucua guccuccucg uacuuggaug cugcuucgca gcaccccgac      120

aacgccaauc cacccuaguc cucuucccug gcgaucuucg aacaaaccug accgaccgcc      180

aacucgcgga agaauaucuc uaccgcuacg gcuacacacg uguagccgaa augcgcggag      240

aauccaaaag ccuaggucca gcacuccucc uccuccaaaa acaacuuuca cuccccgaaa      300

cgggcgaacu cgacuccgcc acccucaaag caaugagaac accacgcugc gggguacccg      360

acuuagggag auuccaaacg uucgaaggag accuaaagug gcaccaccac aacauaacuu      420

acuggauaca aaacuacagc gaggaccugc cccgagcagu caucgacgac gccuucgcaa      480

gagccuucgc ccuauggagc gccguaacac cccucaccuu cacccgugua uacucccgag      540

acgccgacau ugucauccaa uucggcguag ccgaacacgg agacggcuac ccauucgacg      600

gcaaagacgg ccuauuggca cacgcauuuc cacccggccc aggaauacaa ggcgacgccc      660

acuuugacga ugacgaacuc uggagccugg gaaaaggagu cguagucccc accagauucg      720

gcaacgcaga cggagcagca ugccacuucc ccuuuauauu cgaaggccgc ucuuacagcg      780

ccugcacuac cgauggccgc uccgaugguc uacccuggug cuccaccacc gccaacuacg      840

acaccgauga ucgcuucggu uucuguccau cugaaagacu cuacacccag gacggcaacg      900

ccgacggcaa acccugccaa uuuccauuca ucuuccaagg ccaaucuuac uccgcaugca      960

ccacagacgg ccgauccgau ggauaucgcu ggugcgccac aacugccaau uacgaccgag     1020

acaaacucuu cggauucugc ccaacccgag cagacucaac cguaauggga ggaaacucag     1080

ccggcgaauu augcguauuu cccuucaccu uccucggaaa agaguacucc acgugcacca     1140

gcgaaggccg aggagacgga cgacuauggu gcgccaccac aucaaacuuc gacuccgaca     1200

agaaaugggg cuucugcccc gaucaaggcu acucucuguu cuuagucgcc gcacacgagu     1260

ucggacacgc ccugggacua gaccacaguu caguccccga agcgcucaug uaccccaugu     1320

accgcuucac agaaggacca ccacuacaca aggacgacgu aaacggcauc agacaccuau     1380

augguccccg accagaaccc gaaccacgcc cucccacuac cacuacccca caaccaacug     1440

ccccacccac aguaugucca acaggaccac ccaccguaca ccccuccgaa cgccccaccg     1500

ccggcccuac cggaccuccc uccgcagguc ccacaggacc acccacagcc ggccccucca     1560

ccgccaccac aguucccuua uccccugucg acgacgcaug caacgucaac auauucgacg     1620

cuaucgccga aaucggcaau caacuauacc uguucaagga cggcaaauau uggcgcuucu     1680

cagaaggccg aggcagccgc ccucaagguc cauuccucau ugccgacaaa uggcccgccc     1740

uccccagaaa acuugacucc gucuucgaag aacgucucuc caagaaauua uucuucuucu     1800

caggccguca agucuggguc uacaccggcg ccagcguccu cggccccaga cgucuagaca     1860

aacuuggacu cggagccgac gucgcucagg uaaccggggc ucugcgaucc ggacgcggga     1920

agauguugcu auucagcgga cgcagacuau ggcgcuucga cgucaaagcc caaauggucg     1980

acccgagauc cgccuccgaa guugaccgua uguucccagg cgugccccuc gacacccacg     2040

acguauucca auaccgcgaa aaagcauacu ucugccagga ccgcuuuuau uggcgagucu     2100

cuucccgauc ugaacuuaac caagucgacc aaguaggaua ugucaccuac gacauccucc     2160

agugccccga ggacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  3411
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt8)

<400>  3411
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

caggcguccu cgcagcuuuc cucuuccucu ccuggacaca cugccgcgca uuaccccucc      120

ccucaggagg cgacgaagac gaccucuccg aagaggaccu ccaauucgcc gaacguuacc      180

uccgcuccua cuaccacccg acaaaccucg caggaauacu caaggaaaac gccgccuccu      240

ccaugaccga acgccuuaga gaaaugcagu cauucuucgg ccuagaagua accggaaaac      300

uagacgacaa cacccuagac gucaugaaaa aaccccgaug cggugucccc gacgucggcg      360

aauacaacgu cuucccccgc acccuuaagu gguccaaaau gaaccugacc uaucgcauag      420

ucaacuacac gccagacaug acccauuccg aagucgaaaa agcauucaaa aaagcguuca      480

aaguaugguc cgacgucacc ccacuuaacu ucacacgccu ccacgacgga aucgcagaca      540

ucaugauaag cuucgguauc aaagaacacg gcgacuucua ccccuucgac ggcccaucag      600

gccuacuagc ccacgcauuc ccccccggcc cgaauuacgg cggcgacgcc cacuuugacg      660

augacgaaac cuggacaucc uccuccaaag guuacaaccu auuccuagua gccgcacacg      720

aauucggcca cucccucggg cuagaccacu ccaaagaccc cggagcccuc auguucccca      780

uauacacuua caccggcaaa ucccacuuca ugcuacccga cgacgacgua caaggcaucc      840

aaucccugua cggcccaggc gacgaagacc caaaccccaa acaccccaaa acucccgaca      900

aaugcgaccc cucccucucc cuagacgcca ucaccucacu ccgcggcgaa acaaugauau      960

ucaaagaccg uuucuucugg cgccuccacc cacaacaagu agaugcagaa cucuuccuaa     1020

caaaauccuu cuggcccgaa cuaccaaacc gaaucgacgc ugcauaugaa cauccauccc     1080

acgaccucau uuucauauuu cgaggccgaa aauucugggc acuaaacggu uacgacaucc     1140

ucgaaggcua ccccaaaaaa aucuccgaac uaggccuucc caaagaagua aaaaaaaucu     1200

cagccgccgu ccacuuugaa gacaccggaa agacucuacu auucucaggc aaccaagucu     1260

ggcgauacga cgacaccaac cacauaaugg acaaagacua ccccaggcua auagaagaag     1320

acuuuccagg caucggagac aaaguagacg ccguauacga gaaaaacggc uacaucuacu     1380

ucuucaacgg ccccauacaa uucgaguacu ccaucugguc caaucgaauc guacgcguca     1440

ugcccgccaa cucaauccuc uggugcuaag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3412
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt8)

<400>  3412
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaga       60

cccccaacac cacagaagac uacgacacca ccaccgaauu cgacuacggu gacgccaccc      120

ccugucaaaa agucaaugaa cgcgccuucg gcgcacaacu acuaccgccc cucuacucgc      180

ucguuuucgu aaucggccuc gucggaaaua uacucgucgu ccucguccua guccaauaca      240

aacgccucaa aaacaugacu ucaaucuacc uccuuaaccu agccaucucu gaccuccucu      300

uccuauucac acucccauuu uggaucgauu acaaacucaa agacgacugg gucuucggcg      360

acgcaaugug caaaauccua ucaggcuucu acuacaccgg ccuauauagc gaaaucuucu      420

ucauuauccu ucucaccauc gaccgcuacc ucgccauagu ccacgcaguc uucgccuugc      480

gcgcacgcac cguaacuuuu ggagucauaa ccuccaucau cauuugggcu cucgccaucc      540

ucgccucaau gcccggccua uacuucucca aaacacaaug ggaauucacc caccauacuu      600

gcucccucca cuucccacac gagucccuaa gagaauggaa acucuuucaa gcacucaaau      660

uaaaccucuu uggucucguu cuuccccucc ucgucaugau aauuugcuac accggcauca      720

ucaaaauccu ccuccgccgu ccaaacgaaa aaaaauccaa agccguccgc cuaaucuucg      780

uaauaaugau caucuucuuc cucuucugga cccccuacaa ccucacaauc cucaucuccg      840

ucuuccaaga uuuccucuuc acccacgaau gcgaacaauc ucgucaccuc gaccucgcug      900

uccaagucac agaagucauc gcuuacacac acugcugcgu caaccccgua aucuacgcau      960

ucgucgguga acgauuccgc aaauaccucc gccaacucuu ccaccgccgc guagccgucc     1020

accucgucaa auggcuuccc uuccucuccg ucgaccgacu cgaacgcgua ucuagcaccu     1080

ccccuuccac aggagaacac gaacucuccg ccggcuucua aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  3413
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt8)

<400>  3413
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcgca       60

cccucgccug ccuccuccuc cucggcugcg gcuaccucgc ccacguccuc gccgaagaag      120

ccgagauccc acgcgaagua aucgaacgcc ucgcccgcuc ccaaauacac uccauccgcg      180

accuccaacg ccuccucgaa aucgacucag uaggcuccga ggacucacuc gacaccucac      240

uccgcgccca cggcguccac gccaccaaac acguccccga aaaaagacca cucccaaucc      300

gacgaaaacg auccaucgaa gaagccgucc ccgcagucug caaaacccgc accgucauau      360

acgaaauccc acgaucccaa gucgacccca ccuccgccaa cuuccuaauc uggcccccau      420

gcgucgaagu caaacgaugc accggcugcu gcaacacauc cuccguaaaa ugccaaccca      480

gccgcgucca ccaccgcucc guaaaaguag caaaagucga auacguacgc aaaaaaccca      540

aacuaaaaga aguccaaguc cgccucgaag aacaccuaga augcgcaugc gcaacaacau      600

cccuaaaccc cgacuaccgc gaagaagaca ccggccgacc acgagaaucc ggcaaaaaac      660

gcaaacgcaa acgccucaaa ccaacauaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  3414
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt8)

<400>  3414
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacc       60

gaugcugggc acucuuccua ucccucugcu gcuaccuacg ccuagucuca gccgaaggcg      120

accccauccc cgaagaacuc uacgaaaugc ucagcgacca cuccauccga agcuucgacg      180

accuucaacg ccuacuccac ggcgaccccg gcgaagaaga cggagccgaa cucgaccuaa      240

acaugacccg cucccacucc ggcggagaac ucgaaucacu cgcacgcgga cgcagauccc      300

ucggcucccu caccaucgcc gaaccagcca ugauagcaga augcaaaacc cgaacagaag      360

ucuucgaaau cucacgccgc cucauagacc gaaccaacgc caacuuccuc gucuggcccc      420

caugcgucga aguccaaaga ugcuccggcu gcugcaacaa ccgcaacguc caaugccgcc      480

caacccaagu ccaacuccgc ccaguccaag uacgcaaaau cgaaaucgua cgcaaaaaac      540

caaucuucaa aaaagccacc gucacccuag aagaccaccu cgccugcaaa ugcgaaaccg      600

uagccgcagc ccgacccgua acacgcucuc ccggcggcag ccaagaacaa cgagcaaaaa      660

caccccaaac acgcgucaca aucaggaccg uccgcguccg cagaccccca aaaggcaaac      720

accgcaaauu caaacacacc cacgacaaaa ccgcacucaa agaaacccua ggcgcauaag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  3415
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt8)

<400>  3415
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccc       60

ucuucggccu ccuccuccuc accucagccc uagcaggcca acgccaaggc acccaagccg      120

aauccaaccu cuccuccaaa uuccaauucu cauccaacaa agaacaaaac ggcguacaag      180

acccgcaaca ugaacgcaua aucaccguau ccaccaacgg cagcauccac uccccaaggu      240

ucccccauac cuacccccgc aacaccgucc uagucuggcg ccuugucgcc gucgaagaaa      300

acgucuggau ccaacugaca uucgacgaac gcuucggccu cgaagacccc gaagacgaca      360

ucugcaaaua cgauuucguc gaaguagaag aaccuuccga uggcaccauc cucggccgcu      420

ggugcggaag cggcaccguc cccggcaaac aaaucucaaa aggcaaccaa auacgcaucc      480

gauucgucuc cgacgaauac uucccaucag aacccggauu cugcauacac uacaacaucg      540

ucaugccaca auucaccgaa gccgucucac ccuccguccu accccccuca gcccuccccc      600

ucgaccuacu caacaacgcc auaacagccu uuuccacccu cgaagaccuc auccgauacc      660

ucgaaccaga acgauggcag cucgaccuag aagaccucua ccgccccacc uggcaacucu      720

uaggcaaagc cuucgucuuc ggccgcaaau cgcgcguagu ugaccuuaac cuccuaaccg      780

aagaaguacg ccucuacagc ugcaccccac gcaacuucuc cguaucaauc cgcgaagaac      840

ucaaacguac cgacaccaua uucuggcccg gaugccuccu agucaaaaga ugcggcggaa      900

acugcgccug cugccuccau aacugcaacg aaugccaaug cguacccucc aaaguaacca      960

aaaaauacca cgaaguccuu caacuccgcc caaaaacagg cguacguggc cuccauaaau     1020

cacuuaccga cgucgcccuc gaacaccacg aagaauguga cugcgucugu cgcggaucca     1080

ccggaggaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  3416
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt8)

<400>  3416
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

gccucaucuu cgucuacacc cuaaucugcg ccaauuucug cucaugccgc gacaccucug      120

ccacaccgca aagcgcuuca aucaaagcac uccggaacgc caaccugcga cgagacgacc      180

ucuaccgccg cgacgaaacc auccaaguca aaggaaacgg cuacguacaa agcccccgau      240

ucccaaacuc cuacccccgc aaccuccuac ucaccuggag acuacacucc caagaaaaca      300

cccgaauaca acucguauuc gacaaccaau ucggacuaga agaagcugaa aacgacaucu      360

gccgauacga cuucguagaa gucgaagaca uaagcgaaac auccacaauc aucagaggcc      420

gcuggugcgg ccacaaagaa guaccacccc gcaucaaauc ccgcacaaac caaaucaaga      480

uaaccuucaa aucagacgac uacuucgucg ccaaacccgg auucaaaauc uacuacuccc      540

uccuagaaga cuuccaaccc gccgccgccu ccgaaacaaa cugggaauca gucaccucaa      600

gcaucucagg uguaucauac aacucccccu ccgucaccga ccccacacuc auagcagacg      660

cccucgacaa gaaaauagcu gaauuugaca ccgucgaaga ccuccucaaa uacuucaacc      720

ccgaauccug gcaagaagac cucgaaaaca uguaccugga uacaccacgc uacagaggcc      780

gaucauacca cgaccgaaaa aguaaagucg accuugaccg ccucaacgac gacgccaaac      840

gcuauagcug caccccucga aacuacuccg ucaacauccg agaagaacua aaacucgcaa      900

acgucguauu cuucccacgu ugccuccuug uccagcgaug cggaggcaac ugcggcugcg      960

gcaccgucaa cuggcggagc ugcacaugca acuccggcaa aaccguaaag aaauaccacg     1020

aaguacucca auucgaacca ggucacauca aacgucgcgg cagagcuaaa accauggcau     1080

uagucgacau acaacuagac caccacgaac gaugcgacug caucugcagc ucacgacccc     1140

cacgcuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  3417
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt8)

<400>  3417
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguca       60

cacacuccaa auuccccgcc gccggcaugu cccgacccuu agacaccucc uuacgccuaa      120

aaaccuucuc cuccaaaucc gaauaccaac ucguagucaa cgcaguacgc aaacuccaag      180

aauccggauu cuacugguca gccguaaccg gcggcgaagc caaccuccuc cuauccgccg      240

aaccagccgg caccuuccua auucgcgacu cauccgacca acgccacuuc uucacccucu      300

ccgucaaaac ccaauccggc acaaaaaacc uccgcaucca augcgaaggc ggaucauucu      360

ccuuacaauc cgacccccgc uccacccaac cagucccccg auucgacugc guacucaaac      420

ucguccacca cuacaugcca ccccccggcg cccccuccuu cccuucaccc cccaccgaac      480

ccuccuccga agucccugaa caacccucag cccaacccuu acccggcucc cccccacgcc      540

gcgcauacua caucuacuca ggcggcgaaa aaaucccacu cguccucucc cgcccccucu      600

ccuccaaugu agccacacuc caacaccucu gccgcaaaac cgucaacggc caccuagacu      660

ccuacgaaaa aguaacccaa cuccccggac ccauacgcga auuccuagac caauacgacg      720

ccccacuaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  3418
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt8)

<400>  3418
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucc       60

ccuccgccgg ccaacucgcc cucuucgccc ucggcauagu acucgcagcc ugccaagccc      120

uagaaaacuc uaccuccccc cucuccgccg accccccagu agcagccgcc gucgucucac      180

acuucaauga cugcccagac ucccacaccc aauucugcuu ccacggcacc ugccgcuucc      240

ucguacaaga agacaaaccc gccugcguau gccauuccgg auaugucggc gcccgcugcg      300

aacacgccga ccuccuagca guagucgcag caucacaaaa aaaacaagca aucacagcac      360

uugucgucgu cucaaucguc gcccucgccg uacuaaucau caccugcguc cucauccacu      420

gcugccaagu ccgaaaacac ugcgaauggu gccgagcacu caucugccgc cacgaaaaac      480

ccucagcccu acucaaaggc cgaaccgcau gcugccacuc cgaaacaguc gucuaaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  3419
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt8)

<400>  3419
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

cauccggccu acgacuacuc cccuuacucc uaccccuccu auggcuccua guccuaacac      120

ccggccgccc cgcagccggc cuaucgaccu gcaaaaccau cgacauggaa cucgucaaac      180

gcaaacgcau cgaagccauu cgaggacaaa uccuauccaa acucagacuc gccucaccuc      240

ccucccaggg cgaaguacca cccggccccc uucccgaagc aguccucgcc cucuacaacu      300

caacaagaga ccgcgucgcc ggcgaauccg ccgaacccga acccgaaccc gaagccgacu      360

acuacgccaa agaaguuacc cgagugcuaa uggucgaaac ccacaacgaa aucuacgaca      420

aauucaagca gucaacacac ucaauauaca uguucuuuaa uaccucagaa cuccgcgaag      480

caguaccuga acccguccuc cuaucccgcg ccgaacuccg acuucucaga cucaaacuua      540

aggucgaaca acacgucgaa cucuaccaaa aauacuccaa uaauucaugg cgcuaccucu      600

ccaaucgacu ccuugccccc uccgacucac ccgaauggcu cuccuucgac gucaccggag      660

ucguacgcca guggcucucc cgcggcggcg aaaucgaagg cuuccgccuc uccgcacacu      720

gcuccuguga cucccgcgac aauacccuac aagucgacau caacggcuuc accaccggcc      780

gacgcggcga ucucgccacc auccacggca ugaaccgccc auuccuccuc cuaauggcca      840

caccccucga acgugcccaa caucugcaau caucccgcca ccgacgugcc cucgacacca      900

acuacugcuu cuccucaacc gagaaaaauu gcugcguacg acaacuauac aucgacuucc      960

gcaaagaccu cggauggaag uggauccacg aacccaaagg auaccacgcc aacuucugcc     1020

ucggccccug ccccuacauc uggucccucg acacacaaua cuccaaaguu cucgcccucu     1080

acaaccaaca caaucccggc gcaucagcag cccccugcug cgucccccaa gcccuagaac     1140

cccucccaau cgucuacuac gucggccgaa aaccaaaagu cgaacaauua uccaacauga     1200

ucguccgcag cugcaaaugc uccugaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  3420
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt8)

<400>  3420
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugcguacu cuccgcauuc cucauacucc accucgucac cgucgccuua ucuuuaucca      120

caugcucaac ccucgacaug gaccaauuca ugcgcaaacg caucgaagcc auccgaggac      180

aaaucuuauc aaaacucaaa cuaaccuccc cacccgaaga cuaccccgaa ccagaagaag      240

ucccacccga agucauuucc auuuacaacu ccacacgcga ccugcuacaa gaaaaagccu      300

cccgccgcgc cgccgcaugc gaacgcgaac gcucagacga agaauacuac gccaaagaag      360

ucuacaaaau cgacaugcca cccuucuucc ccuccgaaaa cgccauccca cccaccuucu      420

acagacccua cuuccguauc guccgcuuug acgucagcgc aauggagaaa aacgccagua      480

accuugucaa agccgaguuc cgaguauucc gccuacaaaa cccaaaagcc cgcgucccag      540

aacaacgcau cgaacucuac caaauccuaa aauccaaaga ccuaacuucu cccacccaac      600

gauacauaga cucaaaaguu gucaagaccc gcgcagaagg ugaauggcuc agcuucgacg      660

uaacugacgc cguccacgaa uggcuacacc auaaagaccg aaaccuaggc uucaaaauaa      720

gccuccacug cccaugcugc acauucgucc ccucgaacaa cuauaucauc ccgaacaaau      780

cagaggaacu ggaagcccgc uucgccggaa ucgacggaac cuccaccuac accuccggcg      840

accagaaaac cauuaaauca acccgcaaaa agaacagcgg aaaaacccca caccuccuac      900

ucaugcuacu accauccuac cgacuagaau cacaacaaac caaccgcaga aagaaacgcg      960

cccucgaugc cgccuacugc uucaggaacg uccaagacaa cugcugccua cgcccccuau     1020

acaucgacuu caaacgcgac cucggaugga aauggaucca cgaaccuaaa ggcuacaacg     1080

caaacuucug cgccggagca ugccccuacc ucuggagcuc cgacacacaa cacucucgcg     1140

uccucucccu auacaacacc aucaaccccg aagccuccgc cucacccugc ugcgucuccc     1200

aagaccucga accccucaca auacuauacu acaucggcaa aacccccaaa aucgaacaac     1260

uguccaacau gaucgucaaa uccugcaaau gcagcuaggg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  3421
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt8)

<400>  3421
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

ugcaccucca acgcgcccuc guaguccucg cccuccucaa cuucgccaca gucagccucu      120

cccuaucaac cugcaccacc cuagacuucg gccacaucaa aaagaaaaga gucgaagcca      180

uccgcggcca aauccucucc aaacuccguc ucaccagccc acccgaaccc accgucauga      240

cccacguccc auaccaaguc cucgcccuau acaacuccac gcgcgaacua cuagaagaaa      300

ugcacggaga aagagaagaa ggaugcaccc aagaaaacac agaaucagaa uacuacgcaa      360

aagaaaucca caaauucgac augauccaag gacucgccga acacaacgaa cucgccgugu      420

gccccaaagg caucaccucu aaagucuucc gauucaacgu cuccucagua gagaaaaacc      480

gcaccaaccu cuucagagcc gaguuccgag uccucagagu ccccaacccc ucuucaaaac      540

gcaacgaaca acgcauugaa cuguuccaaa uccuacgacc agacgaacac aucgcuaaac      600

aacgauacau aggaggcaaa aaccugccca cccgaggaac agcagaaugg cucuccuucg      660

acgucaccga caccguccgc gaauggcucu uacgccgaga auccaaccuu ggacuagaaa      720

ucuccauaca cugccccugc cacaccuucc agcccaacgg agacauacuc gaaaacaucc      780

acgaagucau ggaaaucaaa uucaaaggag uagauaacga agacgaccac ggacgcggcg      840

accucggccg acucaagaaa caaaaagacc accacaaccc gcaccucaua cugaugauga      900

ucccacccca ucgccucgau aaccccggcc agggcggcca acggaagaaa cgagcacucg      960

acaccaacua uugcuucaga aaccucgaag aaaacugcug cgucagaccc cucuacaucg     1020

acuuccgcca agaccuaggc uggaaauggg uacacgaacc aaaaggcuac uacgccaacu     1080

ucugcagcgg acccugccca uaccuccgau cggcagacac cacccacuca accguccucg     1140

gccucuacaa cacccuuaac cccgaagcau ccgcaucccc cugcugcgua ccgcaagacc     1200

uagaaccccu caccauacua uacuacgucg gccgaacccc aaaagucgaa caauuaucca     1260

acauggucgu caaauccugc aaaugcagcu aaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3422
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt8)

<400>  3422
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

caguagccgu cugggccgcc uuggccguug gccuagaacu cugggccgca gcccacgccc      120

ugccagccca agucgcauuc accccuuacg cccccgaacc cggcagcaca ugccgacucc      180

gcgaauacua cgaccaaacg gcacagaugu gcugcucuaa augcagccca ggccaacacg      240

caaaagucuu cuguacaaaa accagcgaca ccguaugcga cuccugcgaa gacuccacuu      300

auacccaacu cuggaacugg guccccgaau gccucucuug cggcagccgc ugcucauccg      360

aucaagucga aacccaagcc uguacccgcg aacaaaacag aaucuguacc ugcagacccg      420

gcugguacug cgcccucucc aaacaagaag gaugccgacu augcgccccu cuccgcaaau      480

gccgcccagg auucggcgua gcacgccccg gcaccgaaac cucagacguc gucugcaaac      540

cuugugcgcc cggaacauuc agcaacacca ccucauccac cgacaucugc agaccccauc      600

aaauaugcaa cgucgucgcu auccccggaa acgcaucaau ggacgcuguc ugcaccucaa      660

ccucucccac cagauccaug gcaccagggg ccguccaccu accccaaccc gucuccacuc      720

gaucccaaca cacccaaccc acaccagaac cguccaccgc cccauccacc uccuuccucc      780

uccccauggg cccauccccg cccgccgaag guucuaccgg agacuucgcc cuucccgucg      840

gccuuaucgu cggugucacc gcacucggac uccucaucau aggcgucguc aacugcguca      900

ucaugacaca aguaaagaag aaaccacuuu gccuacaacg agaagccaaa guaccccacc      960

uccccgcaga caaagcccgu ggcacccaag gacccgagca acaacaccuc cuaauaaccg     1020

cccccucauc cuccuccuca ucacucgaau cauccgccuc agcacucgac cgcagagcgc     1080

ccacccgcaa ccaaccacaa gcccccggug uagaagccuc cggcgcuggc gaagcccgcg     1140

ccuccacagg aucuuccgac ucuucacccg gcggccacgg cacccaaguc aacguaaccu     1200

gcauagucaa cguaugcucc uccuccgacc acuccucaca augcaguucc caagcaucau     1260

caacaauggg agacacagac uccucccccu ccgaaucccc aaaagacgaa caagucccau     1320

uuucaaaaga agaaugugcc uucagauccc aacucgaaac accagaaacc cuacuuggcu     1380

ccacagaaga aaaaccccuc ccccuaggcg uucccgacgc uggcaugaaa ccauccuaag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  3423
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt8)

<400>  3423
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgg       60

ucaugagauu guucccgugc uuucuccagc uauuggccgg guuagcacua ccggcagugc      120

ccccacaaca gugggcgcuc ucggccggga acgggagcuc ggaaguggaa gugguaccau      180

uccaggaagu gugggggcgc ucguacuguc gagcgcucga gcgauuggua gaugucguga      240

gcgaguaccc aagcgaggua gagcacaugu ucucacccuc augcgugagc uugcucaggu      300

gcacgggcug uugcggggac gagaacuugc acuguguccc gguagagacc gcgaacguga      360

ccaugcaacu gcucaagauc agaagcgggg acaggcccuc guacguggaa uugaccuuua      420

gccagcacgu gcgcugugaa ugucgcccgc ucagagaaaa gaugaagccc gagcgcagac      480

gaccgaaagg gcgcgggaaa aggcgcaggg aaaagcaaag gcccacggac ugucacuugu      540

gcggggacgc ggucccgcgc agguaaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  3424
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt8)

<400>  3424
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

accgccagac cgacaccgcg cccucgccau cauaccaucu cuugcccgga cgcaggagaa      120

cagucgaugc cgcggcaucg cgagggcaag gaccagagcc cgcaccagga ggaggggucg      180

aggggguagg agcgcgcgga guagcgcuca aacuguucgu acaacugcua ggcugcagua      240

gguucggggg agcggucgua cgcgcggggg aggccgaacc aagcggcgcg gccagaagcg      300

caagcagcgg cagggaagaa ccacagcccg aggaaggaga agaggaagag gaaaaagaag      360

aggaaagggg cccacagugg cgacugggag cgcgcaagcc cgggagcugg accggagaag      420

cggcagugug cgcggacucg gccccggcag cacgcgcgcc acaggcccug gccagagccu      480

caggcagggg cgggcgcgug gccaggcgcg gggcagaaga aucaggaccg ccccacagcc      540

caagcaggcg agggagcgca aguagggccg ggcccggccg cgcgagcgaa accaugaacu      600

uccuccugag cuggguccac uggucgcucg cgcuauugcu cuaccuccac cacgcgaaau      660

ggagccaggc cgcgcccaug gcagaaggag gcgggcagaa ccaccacgag guagugaaau      720

ucauggacgu auaccaaagg agcuacugcc accccauaga aacgcuugug gacauauucc      780

aagaauaccc cgacgaaauc gaauacauau ucaaaccgag cugcguccca cucaugcgcu      840

gcggagggug cugcaacgac gaagggcucg aaugcgugcc cacggaagag agcaauauca      900

cgaugcaaau caugcgcaua aaaccgcacc aggggcaaca cauaggggag augucguucc      960

uacaacacaa caaaugcgaa ugccgaccca agaaagaucg agcacgccag gaaaagaaau     1020

cagucagggg caaaggaaag ggccagaaaa gaaaaagaaa gaaaagccgg uacaaaagcu     1080

ggagcguaua cgugggcgcg cgaugcugcc uaaugccgug gagccuaccg ggaccgcacc     1140

caugcggacc cugcagcgag agaagaaaac accuauucgu acaggacccg cagacaugca     1200

aaugcucgug caagaacaca gauucgcgau gcaaagcacg acagcucgag cucaaugaaa     1260

ggacaugcag augugacaaa ccccgacgcu agggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3425
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt8)

<400>  3425
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuccucuc cuggguccac uggucccuag cccuccuacu auaccuccac cacgccaaau      120

ggagccaagc cgcccccaug gccgagggcg gcggacaaaa ccaccacgaa gucguaaaau      180

ucauggacgu auaccaacga agcuacugcc accccaucga aacccucgua gacauauucc      240

aagaauaccc cgacgaaauc gaauacaucu ucaaaccaag cugcguaccc cuaaugcgau      300

gcggcggcug cugcaacgac gaaggccucg aaugcguacc caccgaagaa agcaacauca      360

caaugcaaau caugagaauc aaaccccacc aaggccaaca cauaggcgaa auguccuucc      420

uccaacacaa caagugcgaa ugccgcccca aaaaagaccg cgcccgccaa gaaaagaaau      480

ccguccgugg aaaaggcaaa ggccaaaaac gaaaacgaaa aaaaagccgc uacaaauccu      540

ggagcgucua cguaggcgcc cgaugcugcc uaaugccaug gucccucccc ggcccccacc      600

ccugcggccc cugcuccgaa cgccgaaaac accucuucgu ccaagaccca caaaccugca      660

aaugcuccug caaaaacaca gacucacgcu gcaaagcaag acaacucgaa cuaaacgaac      720

gcaccugccg cugugacaaa ccacgacgau aaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  3426
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt8)

<400>  3426
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucac       60

cacuacuccg ccgacuacuc cucgccgccc uccuccaacu cgcccccgcc caagcccccg      120

ucagccaacc cgacgcccca ggccaccaac gcaaagucgu cuccuggauc gacguuuaca      180

cucgcgcaac augccaaccc cgcgaaguag ucgucccacu caccgucgaa cuaaugggca      240

ccgucgccaa acaacucguc cccucaugcg ucaccgucca acgcugcgga ggaugcugcc      300

ccgacgacgg ccuagaaugc gucccaaccg gccaacacca aguacgcaug caaauacuca      360

ugauccgaua ccccucaucc caacuaggcg agaugucccu cgaagaacac ucccaaugcg      420

aaugccgacc caaaaaaaaa gacuccgccg ucaaacccga ccgagccgcc acaccccacc      480

accgcccaca accccgcucc gucccaggcu gggacucagc ccccggcgca ccaucacccg      540

ccgacaucac ccaccccaca cccgcacccg gccccuccgc ccacgccgcc cccucaacca      600

ccuccgcacu aacccccggc cccgccgccg ccgccgccga cgccgccgca ucaucaguag      660

caaaaggcgg agcauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  3427
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt8)

<400>  3427
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

uccucggauu cuucucagua gccugcuccc uucuggccgc agcccuccuc cccggcccgc      120

gcgaagcccc cgccgccgcc gcagccuucg aauccggccu agaccugagc gacgccgagc      180

ccgacgcagg agaagccacc gccuaugccu ccaaagaccu cgaagaacaa uugcgcucgg      240

ucucgucagu cgacgaacuc augaccgucc ucuacccaga auacuggaaa auguauaaau      300

gccaacuccg caaagguggc uggcaacaca accgggaaca agccaaccuc aacagccgaa      360

cagaagaaac aaucaaauuc gccgcagccc acuacaacac agaaauccuc aaauccauag      420

acaacgaaug gcgcaaaacc caaugcaugc cccgcgaagu gugcaucgac guaggcaaag      480

aguucggcgu cgccacaaac acauucuuca aaccaccgug cgucuccguc uaccgcugug      540

gcggaugcug caacucggaa ggacuacaau gcaugaacac guccaccucc uaccucucca      600

aaacccucuu cgaaauaacc guaccacuau cccagggucc aaaacccgua acaauauccu      660

ucgcaaacca uacuuccugc cgaugcaugu ccaaacuuga cgucuacaga cagguacaca      720

gcauaauccg gcguucccua cccgcuaccc uaccacaaug ccaagcagcc aauaaaaccu      780

guccaacaaa cuacaugugg aacaaccaca ucugucgcug ccucgcccaa gaagacuuca      840

uguucuccuc agacgccggc gacgacucaa cagacggcuu ccacgacauc uguggcccaa      900

acaaagaacu ugaugaagaa acaugccaau gcgucugccg agccggacuc cgacccgcaa      960

gcugcggccc ccauaaagaa cuagaccgga acucaugcca augcguaugu aaaaauaaac     1020

uauuccccuc ccaaugcggc gccaaccggg aguucgacga aaauaccugc caaugcguau     1080

gcaaacgcac uugcccacgc aaccaacccc uaaaccccgg caaaugcgcc ugcgaaugca     1140

ccgaaucgcc ccaaaaaugc cuacucaaag gcaagaaauu ccaccaccaa accugcuccu     1200

guuaccgccg acccugcacc aaccgccaaa aagccugcga acccgguuuc ucauacucag     1260

aagaggucug ccgaugcguc cccagcuauu ggaaacgccc acaaaugucc uaaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  3428
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt8)

<400>  3428
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguacc       60

gugaaugggu cgucgucaac guauucauga ugcuauacgu ucaacucguc caaggauccu      120

caaaugaaca cggcccaguc aaacgcagcu cccaauccac acucgaacgc uccgaacaac      180

aaauccgcgc cgccuccucc cucgaagaac uacuucgcau cacccauuca gaagacugga      240

aacuauggcg augccgccuc cgccucaaau cauuuaccuc aauggacagc cgcucagccu      300

cccaccgcuc cacacgcuuc gcggccacuu uuuacgacau agaaaccuua aaagucauag      360

augaagaaug gcaacgcaca caaugcuccc ccagagaaac cugcgucgaa gucgccuccg      420

aacucggcaa aucaaccaac accuucuuca aacccccaug cgucaacgua uuccguugcg      480

gaggcugcug caacgaggaa ucauuaaucu gcaugaacac aagcacaucc uacaucucca      540

aacaacucuu cgaaaucucu guaccccuca ccuccguccc cgaauuagua ccugucaaag      600

ucgcaaacca cacaggaugc aagugccucc cuaccgcacc ccgccacccc uacuccauaa      660

uccggcgauc cauccaaauc cccgaagaag accgaugcuc acacucaaag aaacucugcc      720

ccaucgacau gcucugggac uccaacaaau gcaaaugcgu ccuccaagaa gaaaaccccc      780

uagccggcac cgaggaccac ucccaccuac aagaaccagc ccucugcggc ccccacauga      840

uguucgacga agaccgaugc gaaugcgucu gcaaaacccc cugccccaaa gaccucaucc      900

aacaccccaa aaacugcucc ugcuucgaau gcaaagaauc ccuagaaacc ugcugccaaa      960

aacacaaacu auuccaccca gauaccugcu caugcgaaga ccgcugcccc uuccacacac     1020

gccccugcgc cuccggcaaa accgccugcg ccaaacacug ccgauucccc aaagaaaaac     1080

gcgccgccca aggaccccac ucccgcaaaa accccuaagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  3429
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt9)

<400>  3429
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

ccgacgaaac cggcuucgaa cacuccggcc ucugggucuc cguccucgcc ggccuccucc      120

uaggcgccug ccaagcacac cccauacccg auucuucccc acuacuccaa uucggcggcc      180

aaguccgcca acgcuaccuc uacacagacg acgcccaaca aacagaagcc caccuagaaa      240

uccgagaaga cggcacaguc ggaggcgccg ccgaccaauc acccgaaucc cuccuacaac      300

uaaaagcccu caaacccggc gucauccaaa uccucggcgu caaaaccagc cgauuccucu      360

gccaacgccc cgacggcgcc cucuacggau cccuacacuu cgacccagaa gccugcuccu      420

uccgcgaacu ccuccuagaa gacggcuaca acgucuacca aucagaagcc cacggccucc      480

cccuccaccu ccccggcaac aaaucaccac accgcgaccc agccccacgc ggccccgccc      540

gcuuccuucc ccuccccggc cucccacccg cacuccccga acccccaggc auccucgcac      600

cccaaccccc agacgucggc uccucagacc cccucuccau ggucggcccc ucucaaggca      660

gauccccauc cuacgccucc uaaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  3430
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt9)

<400>  3430
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

ccuucccucc ccuccuacua cuccucuucu ggggcguugu cucccacucc uuccccgcga      120

cccuagaaac acaggaacaa gacguugacc ucguccaaaa auaccuagaa aaauacuaca      180

accucaaaaa cgacggacgc caaguagaaa aacgacgcaa cuccggcccc gucgucgaaa      240

aacucaaaca gaugcaagag uucuucggcc ucaaggucac cggcaaaccc gacgccgaaa      300

cacuaaaagu aaugaaacaa ccccgcugcg gcguacccga cgucgcccaa uucguacuca      360

ccgaagguaa cccacgcugg gaacaaaccc accucacuua ccggaucgaa aacuacaccc      420

ccgaccuccc ccgcgccgac gucgaccaug ccaucgaaaa agccuuccaa cucuggucaa      480

acgucacacc ccucaccuuc accaaagucu cugaaggcca agcagacauc augauaucau      540

ucguacgagg cgaccaccga gacaacuccc ccuucgacgg cccgggaggc aaccuggcac      600

acgccuucca accaggucca ggaaucggcg gcgacgcaca cuuugacgag gacgagcgau      660

ggaccaacaa cuuccgagaa uacaaccucc accgcgucgc agcccacgag cucggccacu      720

cacugggacu cucacacucc accgauaucg gagcacucau guaucccucu uacacuuucu      780

ccggcgacgu acaacuagcc caagacgaca uagacggaau ccaagcaauc uacggacgcu      840

cccagaaccc cguccagccc aucggaccuc aaacaccaaa agccugcgac uccaaacuaa      900

cauucgacgc caucacaacc auacgaggcg aagucauguu cuucaaagac agauucuaca      960

ugcgcacaaa cccuuucuau cccgaagucg agcucaacuu caucuccguc uucuggcccc     1020

aacuccccaa cggccuugaa gcagccuacg aguucgccga ccgcgacgaa guccgauucu     1080

ucaaaggaaa caaauacugg gccguccaag gccaaaacgu ccuacauggc uaccccaaag     1140

acauauacuc cuccuucggc uucccaagaa ccgucaaaca caucgacgca gcacucuccg     1200

aggaaaacac cggaaaaacc uacuucuucg ucgcaaacaa auacuggcgc uacgacgaau     1260

acaagcgcuc aauggacccc ggcuauccaa aaaugaucgc acacgacuuc cccggcaucg     1320

gucacaaagu cgaugcuguu uucaugaaag acggcuucuu cuacuucuuc cacggaaccc     1380

gccaauacaa auuugaccca aaaaccaaac gcauccucac acuacaaaaa gccaacagcu     1440

gguucaacug ccgcaaaaac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  3431
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt9)

<400>  3431
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

ccuucccacc ccuacuccuc cuacucuucu ggggcguagu cucccacuca uucguacuca      120

ccgaaggcaa cccccgaugg gaacaaaccc accucaccua ccgcauagaa aacuacaccc      180

ccgaccuccc ccgcgccgac guagaccacg ccaucgaaaa agccuuccaa cucuggucca      240

acguaacacc ccucaccuuc accaaagucu ccgaaggcca agcagacaua augauaucau      300

ucguccgcgg cgaccaccga gacaacucac ccuucgacgg ccccggcggc aacuuagccc      360

acgccuucca gcccggccca ggcauaggcg gagacgcaca cuucgaugaa gacgaacgcu      420

ggaccaacaa cuuccgcgaa uacaaccucc accgcgucgc agcccacgaa cucggccacu      480

cccuuggacu cucacacucc accgacaucg gagcccuaau guacccauca uacacauucu      540

caggcgacgu acaacucgcc caagacgaca ucgacggcau acaagcaauc uauggccgcu      600

cacagaaccc aguacaacca aucggccccc aaacccccaa agccugcgac uccaaacuca      660

ccuucgacgc aauaaccaca auucgaggag aagucauguu cuucaaagac cgauucuaca      720

ugcgcaccaa ccccuucuac cccgaaguag aacucaacuu cauauccguc uucuggccuc      780

aacuacccaa cggccucgaa gcagcauacg aguucgccga ccgagacgaa guccgauucu      840

ucaaaggcaa caaauacugg gccguccaag gccaaaacgu ccuacacggc uacccaaaag      900

acaucuacuc uuccuucggc uucccacgaa caguaaaaca cauagacgca gcucucucag      960

aagaaaacac cggcaaaacu uacuucuucg uagcaaacaa auacuggcgc uacgacgaau     1020

acaaacgcuc uauggacccc ggauacccca aaaugauagc ucacgacuuc cccggcauag     1080

gucacaaagu cgacgcagua uucaugaaag acggcuucuu cuacuucuuc cacggcaccc     1140

gccaauacaa auuugacccc aaaaccaaac gcauccucac ccuucaaaaa gccaacuccu     1200

gguuuaacug ucgcaaaaac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  3432
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt9)

<400>  3432
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

agaacauccu aaagauacuc auggacagcu acagcaaaga aucgaaaauc caaaccguuc      120

gucgaguaac cuccguaagc cuccuagccg uauaucugac caugaacacg agcagccucg      180

uacuagccaa acccauagaa aacaccaacg auaccucaau caaaaacgua gaaaaacuga      240

ggaacgcacc caaugaagaa aacucaaaga aaguugaaga cagcaaaaau gacaaggucg      300

aacacgucaa aaacaucgaa gaagcaaaag uagagcaagu agcccccgag guaaaaagca      360

aaagcacgcu cagaucagca agcauugcca acacaaacag cgaaaaauac gacuucgaau      420

accuaaacgg ucuaagcuau accgaacuga cgaacuuaau aaagaacauc aaauggaacc      480

aaauaaacgg ccuauucaac uacuccacag gcagccaaaa auucuucggg gacaaaaaca      540

gaguacaggc aauaaucaac gcgcuccagg aauccggccg uaccuacacg gcgaacgaca      600

ugaaggggau cgaaacauuc accgaaguac uccgugccgg cuucuaccuu ggguauuaca      660

augacggacu cagcuaccuc aacgaccgca acuuucagga caagugcauc cccgcaauga      720

ucgcaaucca aaagaacccu aauuucaaau uaggaacagc cguacaggac gagguaauca      780

cgagccuggg caaauuaauc ggcaacgccu cugcgaacgc agaggucguc aacaacugug      840

ugccaguccu caagcaguuc cgggagaacc ugaaucaaua cgcacccgac uacguaaagg      900

gcacugccgu caacgaacuc auaaaaggca uagaguucga cuucucaggc gccgccuacg      960

aaaaagacgu uaaaacgaug cccugguacg gaaaaauaga ccccuucaua aacgaauuaa     1020

aagccuuagg ccucuacggc aacaucacca gcgcaacgga augggccuca gacguaggua     1080

ucuacuaucu uuccaaauuc ggauuauaca gcaccaaccg caacgacaua guacaauccc     1140

uagagaaagc cgucgauaug uacaaauacg gaaaaauagc guucguagcc auggaacgaa     1200

ucaccuggga cuacgacggc aucggcucaa acggcaagaa agucgaccac gacaaauucc     1260

uggacgacgc cgaaaaacac uaucucccca aaaccuacac auucgacaac gggacguuca     1320

uaauccgcgc gggcgacaaa guauccgaag agaaaaucaa acgccuauac ugggccucca     1380

gagaaguuaa aagccaauuu caccgggugg uggggaacga caaagcccua gaagucggaa     1440

acgccgauga cguccucaca augaaaaucu ucaauagucc cgaagaauac aaauucaaca     1500

ccaacauaaa cggcguuagc accgacaaug ggggccugua caucgaaccc cggggcacau     1560

ucuacaccua cgaaagaacg ccucaacaau cuaucuucag ucuggaggag uuguuccgcc     1620

acgaauacac ccacuaccua caagcacguu accucgucga cggccuaugg ggccagggac     1680

ccuuuuacga aaagaacagg cuaaccuggu ucgacgaggg cacagccgag uucuucgccg     1740

ggagcacccg cacauccgga guacugccca ggaaaagcau ccucggcuac cuugccaaag     1800

auaaaguuga ccaucgcuac ucacugaaga agacccuuaa cagcggauau gacgauagcg     1860

acuggauguu cuacaacuau ggguucgcgg uagcacacua ccuauaugaa aaagacaugc     1920

ccacuuucau caaaaugaau aaggcaaucc ucaacaccga cgucaaaucc uacgacgaaa     1980

ucauuaagaa acugagcgac gacgcaaaca agaacaccga guaccagaac cacauccagg     2040

agcuagccga caaguaccag ggggcaggaa ucccccuagu aucagacgac uaccucaaag     2100

aucacggcua caagaaagcg agcgaaguau acuccgaaau aucgaaggca gcaagccuca     2160

cgaacacaag cgugacagcc gaaaaaucac aauacuucaa caccuucacu cuccggggua     2220

ccuacacagg cgagaccucc aagggagaau uuaaagacug ggacgaaaug agcaaaaagc     2280

ucgacggcac ccucgaauca cucgccaaaa acuccugguc cggcuacaag acauuaacug     2340

cauacuucac uaauuaccgc gucaccagcg acaacaaagu ccaauacgac gucguuuucc     2400

acgggguacu aaccgauaac gcagacaucu ccaacaacaa agcaccuauc gcaaaaguca     2460

cgggaccauc cacuggggcc guuggacgca auauugaguu cucagguaaa gacagcaaag     2520

acgaggacgg caaaaucguc agcuacgacu gggauuucgg agacggcgcg acaucacgag     2580

gcaaaaacag cguccacgca uauaagaaag ccggcaccua caacguuaca cuaaagguca     2640

cagacgacaa aggagcaaca gcgacagagu cauucacaau agagaucaaa aacgaggaca     2700

cgacgacacc uaucacaaaa gaaauggaac cgaacgacga caucaaagaa gccaacggcc     2760

caauagucga aggaguaacc guuaaaggcg accucaacgg cucagaugac gccgauaccu     2820

ucuacuucga cgucaaggaa gacggggacg uaacaauuga acuaccauac ucagggucaa     2880

gcaauuucac auggcucguc uacaaagaag gcgacgauca gaaccauaua gcaucaggca     2940

uagacaaaaa caacucgaaa gugggcaccu uuaaaagcac aaaaggccgc cacuacgugu     3000

ucauauacaa acacgacagc gccucgaaca ucucuuacuc acuaaacauc aagggccuag     3060

gaaacgagaa gcugaaagaa aaagaaaaca acgacucuuc agauaaggcc accgucauuc     3120

ccaacuucaa cacaacaaug caaggcucgc ugcucggcga cgacuccaga gacuauuacu     3180

ccuucgaggu aaaagaagaa ggagaaguca acaucgaauu ggacaagaaa gacgaguucg     3240

gggugacaug gacccuucac ccggaaucca acauaaacga caggauaacc uacgggcaag     3300

uagauggaaa caaagugucg aacaaaguca agcuccgacc cggcaaauac uacuugcuag     3360

ucuacaaaua cagcggcucu ggcaacuacg aacuacgagu aaacaaauag ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  3433
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt9)

<400>  3433
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

gggugacuuu cauuucccug cuguuccucu ucagcagcgc cuacuccauc gcaaacacaa      120

acagcgaaaa auacgacuuc gaauaccuga acggacucag uuacaccgaa cucacaaacc      180

ucaucaagaa caucaagugg aaccaaauaa acggccucuu caacuacucg accggcuccc      240

aaaaguucuu cggggauaag aaccgcgucc aagccauuau caacgcccuc caagaaagcg      300

ggcgcacaua caccgccaac gacaugaagg gcauagaaac auuuacagaa gugcuacgcg      360

cgggcuucua ccucggcuau uacaacgacg gacucagcua ccuaaacgac cgaaacuucc      420

aggacaagug cauaccggca augauagcca uccagaaaaa ucccaacuuu aaacucggaa      480

cugccgugca agacgaagua aucaccucgc ucggaaaacu aaucggcaac gccucagcca      540

augccgaagu agucaauaac ugcguccccg ucuuaaagca auuccgagag aacuugaacc      600

aauacgcacc agacuacguc aagggcaccg ccguaaacga guuaaucaaa gggauagagu      660

ucgacuucuc gggagccgca uaugaaaaag acgucaaaac caugccaugg uacggcaaaa      720

ucgaccccuu cauaaacgaa cucaaagccc uuggccuaua cggcaacaua acaagcgcga      780

cagaaugggc cagcgacgua ggcaucuacu accuaucaaa guucggacuc uacagcacca      840

accggaacga cauaguccaa agccucgaaa aagcaguaga cauguacaaa uacggcaaaa      900

uagccuucgu cgcaauggag cgcauaacau gggauuacga cgggaucggc aguaauggua      960

agaaaguaga ccaugacaag uuccucgacg acgcagaaaa acacuaccua ccuaagacau     1020

acaccuucga caacggaacc uucauaaucc gcgcaggcga caaaguuagu gaggagaaaa     1080

ucaaaagacu auacugggca ucaagagaag ucaaaucaca auuccaccgc guagucggca     1140

acgacaaagc ccucgaagug gggaacgccg acgacguccu aacaaugaaa aucuucaaca     1200

gccccgaaga auacaaauuc aauacuaaua uaaacggagu aagcacagac aacggcggcc     1260

uauauaucga accccgcggg acuuucuaua ccuacgaaag gacgccgcaa caauccauau     1320

ucucacuaga agaacuauuc cgccacgaau acacccacua ccuccaggca agauaccuag     1380

ucgacggccu auggggucag ggcccauucu acgaaaagaa ccgccuaacc ugguucgacg     1440

agggaacagc cgaauuuuuc gccggaucca cccgcacaag cggaguccug ccccgcaaau     1500

caauacucgg guaccuagcg aaagacaaag uggaccaccg auacagccua aagaaaacac     1560

ucaacuccgg auacgaugac agcgacugga uguucuacaa cuacggauuc gccgucgcac     1620

acuaccuaua cgagaaagac augcccacuu ucaucaaaau gaacaaagcg auacucaaca     1680

ccgacgucaa aagcuacgac gagaucauca agaaacuguc cgacgacgca aauaaaaaca     1740

ccgaauacca gaaccacauu caggaacucg ccgacaaaua ccaaggagcc ggcaucccac     1800

ucgucagcga cgacuaccuc aaagaccacg gguacaaaaa ggcguccgaa guauauucug     1860

agaucagcaa agccgcaucc cugaccaaca caucagucac agcagagaaa ucucaguacu     1920

ucaacacauu cacgcuccgg gggaccuaca caggcgaaac uagcaaaggg gaguucaagg     1980

acugggacga gaugagcaag aaacuggaug gcacacucga gagucucgcg aaaaacuccu     2040

ggucgggcua caaaacgcuu acagcauauu ucaccaacua ccgcgucacc ucagacaaca     2100

aaguccaaua cgacgucgug uuccacggag ugcucaccga caacgccgac aucuccaaca     2160

acaaggcacc uaucgcaaag gugaccggcc ccucaacagg cgcgguugga cggaacaucg     2220

aguucuccgg gaaagacagu aaggacgagg acggcaaaau aguaagcuac gacugggacu     2280

ucggagacgg ggcgaccucc cgaggcaaga acagcgucca cgccuacaag aaagccggca     2340

cauacaacgu gacacuuaaa guuaccgacg acaaaggagc caccgccacg gaguccuuua     2400

ccaucgagau caaaaacgaa gacaccacaa ccccaauaac caaagaaaug gaaccuaacg     2460

acgacauuaa ggaggcaaac ggcccaauag uagaaggagu uacggucaag ggugaccuca     2520

acgguuccga ugacgcagac accuucuacu ucgacgucaa agaagacggg gauguaacca     2580

ucgaacuacc cuacuccgga uccucaaauu ucacuuggcu aguauacaag gagggcgacg     2640

accaaaacca cauagccucg gggauagaca aaaacaacuc uaaaguagga accuuuaagu     2700

ccacaaaggg acggcacuac gucuuuaucu acaagcacga cuccgcuucc aacauaucgu     2760

acucguuaaa caucaaagga cuaggaaacg aaaaacucaa agagaaagaa aacaacgacu     2820

caucggacaa agcgacagua auaccaaacu ucaacaccac gaugcagggc ucccuauugg     2880

gagaugacag ccgagacuac uacucguuug aaguaaaaga ggaaggcgaa gucaacaucg     2940

aacuagauaa gaaagacgag uucggaguua cguggacccu ccaccccgag agcaacauca     3000

augaccgaau uaccuauggc caggucgacg guaacaaagu aucuaauaaa gucaaacucc     3060

gcccaggcaa auacuaccuc cucgucuaca aguacagcgg uagcggcaac uacgaacuac     3120

gcgugaauaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  3434
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt9)

<400>  3434
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugacauu caucucccua cuguucuuau uuaguuccgc cuauaguaug aaaaagaaca      120

uucucaaaau ccucauggac agcuacagca aagagagcaa gauccagacc gugcgucgag      180

uaaccagcgu cagcuuacua gcgguauacc uaaccaugaa cacauccagc cuaguccugg      240

caaaacccau cgaaaacacc aaugacacuu ccaucaagaa cgucgagaag cuacgaaacg      300

caccaaacga agagaauagc aagaaaguug aagauuccaa aaaugacaaa guagagcacg      360

ucaaaaacau cgaagaagca aaagucgaac aaguagcccc ggaagucaaa uccaagagca      420

cgcuccgcuc cgccaguaga cggcgcagga aacgcaucgc aaacacaaac uccgagaaau      480

acgacuucga auacuugaac ggauuaagcu acacggagcu aaccaaccuc aucaaaaaua      540

uaaaauggaa ccaaauaaac ggccuauuca acuauagcac cgggucccag aaauucuucg      600

gagauaagaa ccgcguacaa gcuaucauca augcccugca ggaauccggc cgcacauaca      660

cggccaacga caugaaaggu auagaaacau ucacagaagu gcuaagggcc ggcuucuacc      720

ucggcuacua caacgacggg cuaucauacc uaaaugacag aaauuuucag gacaaaugca      780

uaccggcuau gaucgcgaua cagaaaaacc cgaacuucaa gcuaggcacg gccguacaag      840

acgaagucau caccuccuug ggaaaacuca uaggcaacgc cuccgcgaac gccgaagucg      900

ucaacaacug uguacccguc cuaaaacagu uuagagagaa ccuaaaccag uacgcuccgg      960

acuacgucaa agggacagca gugaaugaac ugauuaaggg aauagaguuc gacuucucag     1020

gcgcugccua cgaaaaggac gugaaaacca ugcccuggua cggcaagauc gacccauuca     1080

ucaacgaauu aaaagcacuc ggccuauaug gcaacauaac cuccgccacc gaaugggcau     1140

cggacgucgg aauauacuac cucaguaaau uuggacugua uagcaccaac agaaacgaca     1200

ucguccaaag ccucgagaaa gcagucgaca uguacaaaua cggcaaaaua gccuucgugg     1260

caauggaaag gaucacaugg gacuacgacg gcaucggguc caacggaaag aaaguagacc     1320

acgacaaauu ucuugacgac gccgagaaac acuaccuacc aaaaacuuac accuucgaca     1380

acggcaccuu cauaaucaga gcaggagaca aagucagcga agagaaaauc aaacggcuuu     1440

acugggccuc acgugaagug aaaagccagu uccaccgcgu cgugggaaau gacaaggcau     1500

uggaaguagg gaacgcggac gacguccuaa caaugaaaau auucaacagc ccagaagaau     1560

acaaauucaa cacuaacaua aauggagucu ccaccgacaa cggcggccuc uacauagaac     1620

caaggggcac cuuuuacaca uacgaacgca caccucagca aagcauauuu ucacuagaag     1680

aacucuuccg ucacgaauac acccacuacc uccaggcuag auaccucguu gacggacugu     1740

ggggccaggg ccccuuuuau gagaaaaacc gccucacgug guucgacgaa ggcacagccg     1800

aguucuucgc cggcagcaca cgaaccagcg gcguacuacc acgaaaaucg auccucggcu     1860

accuggcaaa agacaaaguc gaucauaggu acagccucaa aaagacacua aacagcggau     1920

augacgacuc ugacuggaug uuuuacaacu acggguucgc cgucgcacac uaccucuacg     1980

aaaaggacau gcccacauuc aucaaaauga acaaggcgau ccuaaacacu gacguaaaaa     2040

gcuacgacga aauaauaaag aagcuaagcg acgaugccaa caagaacaca gaguaccaaa     2100

accacauuca ggaacuugcc gacaaauacc agggagccgg aaucccgcuc guauccgacg     2160

acuaccuaaa agaccacgga uacaaaaagg cauccgaagu cuacagcgaa auaagcaagg     2220

ccgcgucacu aacaaacacg ucagucaccg cagagaaauc ccaauacuuc aacaccuuua     2280

cacugagagg gacauacacc ggcgaaaccu caaaaggaga guucaaagac ugggacgaaa     2340

uguccaagaa acuagacgga acacucgaau cgcuagcuaa aaacuccugg agcggauaca     2400

aaacccucac ggcuuauuuc accaacuacc gcgucacgag cgacaacaag guacaauaug     2460

acguugucuu ccacggcguc cucacggaca acgccgacau cucaaacaau aaggccccca     2520

uagcaaaagu aacaggacca uccaccggcg cagucggccg aaacauagag uucucaggca     2580

aagauuccaa agacgaagac gggaaaaucg uuaguuacga uugggacuuc ggcgacggcg     2640

ccaccucgcg agguaagaac uccgugcacg cauacaaaaa ggccggaacc uacaacguua     2700

cccuaaaggu gacagacgac aaaggagcga cggcgacaga aucuuucaca aucgaaauca     2760

aaaacgaaga cacuacaaca cccaucacga aagaaaugga gcccaacgac gacaucaagg     2820

aagcaaacgg gccgaucguu gaaggaguaa ccgucaaagg agaccucaac gggagcgacg     2880

acgcagacac cuucuacuuc gaugucaaag aggacgggga cguaacaauc gagcuccccu     2940

acucaggaag cagcaacuuc acauggcuag uguacaagga gggcgacgac cagaaccaca     3000

uagcguccgg caucgacaaa aacaacucaa aaguaggcac cuucaaaagu accaaaggcc     3060

gccacuacgu uuucaucuac aagcacgacu ccgccuccaa cauaagcuac ucgcuaaaca     3120

ucaagggcuu aggcaacgaa aaacugaaag aaaaagaaaa caacgacuca ucugacaagg     3180

ccaccguaau acccaauuuc aacacaacca ugcagggcuc acugcucgga gacgacucac     3240

gagauuacua cuccuuugaa guaaaagaag aaggcgaagu aaacaucgaa uuggauaaga     3300

aagacgaguu cggcgugacg uggacacuuc acccagaauc aaacaucaac gacaggauaa     3360

ccuaugggca aguagacggc aacaaaguau cuaacaaggu caagcuccgc cccggcaagu     3420

acuaccugcu cgucuacaaa uacagcggau cuggaaacua ugaacuccgc guaaacaaau     3480

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  3435
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt9)

<400>  3435
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccucaaaau cauacugaac cgcggaaaaa ccaugaagag aaagugccua uccaaaaggu      120

uaaugcucgc cauaaccaug gccacgauau ucacagugaa cucgacccuc ccgauuuacg      180

ccgccguaga caaaaacaac gcgaccgccg cgguacagaa cgaguccaaa cgguacacgg      240

uauccuaucu caagacccuc aacuacuacg acuuggucga ccuucucguc aaaacagaga      300

uagaaaaccu ucccgaucua uuccaauacu cuagcgacgc caaagaguuc uacggaaaca      360

aaacaagaau gucguucauc auggacgaga ucggccgccg cgcuccucaa uacacagaaa      420

uagaccacaa aggcauaccc acccuggucg aggucguccg cgccggcuuc uaccuagguu      480

uccacaacaa agaacuaaac gaaaucaaca agcgcagcuu caaagaaagg gucauacccu      540

ccauacuggc uauccagaaa aaccccaacu ucaaauuggg aaccgaagua caagacaaaa      600

uagucucagc cacaggccug cucgcaggua acgagacugc accaccggaa gugguaaaua      660

acuucacccc gauacuccaa gacuguauca agaacaucga ccguuacgcc cucgacgauc      720

ucaaaagcaa agcacucuuc aacgugcucg cagcaccaac guaugauauc acugaauacc      780

ugagagcaac caaagaaaaa ccggagaaca cccccuggua cgggaaaauc gacggguuca      840

uaaacgaauu gaagaaacug gcccuuuacg gcaaaauaaa cgacaauaac ucauggauaa      900

ucgacaacgg aaucuaccac auagcacccc ucggcaaacu ccacaguaac aacaaaauag      960

ggaucgagac ccuaaccgaa gugaugaagg uuuaccccua ucucucaaug cagcaucucc     1020

agagugcaga ccaaauaaaa aggcauuacg acucaaaaga cgccgagggc aacaagauac     1080

cucucgacaa guucaagaaa gagggcaaag aaaaguacug ccccaaaacc uacacguuug     1140

acgaugguaa agucaucaua aaggcaggag cacgagucga agaagaaaaa gucaaacguc     1200

uuuacugggc cagcaaggaa guaaacagcc aguucuuccg agucuacggc aucgacaaac     1260

cacucgagga aggcaacccg gaugacaucc ucacaauggu gaucuacaac agcccggagg     1320

aguacaaacu uaacuccguc uuguacggcu augacaccaa caauggcggg auguacaucg     1380

aaccagaagg aacuuucuuc accuaugagc gcgaagccca agaguccacc uauacccucg     1440

aggaacucuu ccgacacgaa uacacucauu acuuacaagg ccgcuacgca guacccgggc     1500

aauggggccg caccaagcua uacgacaaug acagacuaac uugguacgag gaaggcggag     1560

ccgaacuauu cgcaggcucc acacgcaccu caggaauacu cccucgcaaa agcauaguau     1620

ccaacauaca caacaccacc cgaaacaaca gauauaaacu aagcgacacc guccacagca     1680

aauacggagc gagcuucgag uucuacaacu acgccugcau guuuauggac uauauguaca     1740

acaaagauau gggcauacuc aacaaacuua acgaccuagc aaagaacaac gacgucgacg     1800

gcuacgacaa cuacauacgg gaccucagcu cgaacuaugc acuaaacgac aaauaccaag     1860

accacaugca ggaacgcaua gacaacuacg aaaaccucac cguacccuuc gucgcagacg     1920

acuaccuagu ccgacacgcg uacaaaaauc ccaacgaaau cuacuccgaa aucagcgaag     1980

ucgccaagcu gaaggaugcc aaaagcgaag ugaagaaauc acaauauuuc ucaaccuuca     2040

cgcuccgcgg cucauacaca gguggcgccu ccaaaggaaa acuagaggau caaaaagcaa     2100

ugaacaaguu cauagacgac ucccucaaaa agcucgacac auacuccugg uccggcuaca     2160

aaacacuuac cgcguacuuc accaacuaca aaguagacuc cucgaaucga guaaccuacg     2220

acgucguauu ccacggcuac cuuccaaacg aaggcgacuc caaaaacucc cuacccuacg     2280

gaaagauaaa cggcaccuac aaagguaccg aaaaggagaa aaucaaauuc uccagcgaag     2340

ggucauuuga cccagacgga aaaaucgucu ccuacgaaug ggacuucgga gacggaaaua     2400

agucaaacga agaaaacccc gaacacagcu acgacaaagu gggaaccuac accguaaagc     2460

ucaaagugac agaugacaaa ggcgaaucaa guguaaguac gaccacugcu gagauaaaag     2520

acuugucgga gaauaaacuu cccguaaucu acaugcacgu ccccaaauca ggagcacuaa     2580

accagaaagu cguauucuac ggcaaaggaa ccuacgaccc cgacggcuca auagccggau     2640

aucaauggga uuucggggac ggaagcgacu uuucgucgga acagaacccc agccacgugu     2700

acacgaagaa aggggaauac accgucaccc ugcggguaau ggacagcuca ggccaaaugu     2760

ccgagaaaac aaugaaaaua aaaaucaccg accccgucua ccccaucggc acggaaaaag     2820

aacccaacaa cuccaaagaa accgcauccg gcccaaucgu gcccggcaua cccgucuccg     2880

gcacaauaga aaauaccucc gaccaagacu acuucuauuu cgaugucauc acccccggag     2940

aggucaaaau cgacaucaac aaacugggcu acggcggagc aaccugggua gucuacgacg     3000

agaacaacaa cgccgucagu uacgcaaccg acgacgggca aaaccucagc ggaaaguuca     3060

aagccgacaa accaggaaga uacuacaucc accuauacau guucaauggc agcuacaugc     3120

ccuacagaau uaauaucgag ggauccgugg gccgcuaagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  3436
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt9)

<400>  3436
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaac       60

gaaaaugccu uagcaaacgc cugaugcucg ccauuaccau ggcgacaaua uucaccguga      120

acaguacgcu cccuaucuac gcagccguag acaaaaacaa cgcaaccgca gccguacaga      180

acgaguccaa acgcuacacc gucuccuauc ucaagacccu aaacuacuac gaccuuguag      240

accuccucgu gaagaccgaa aucgaaaacc uacccgaccu cuuccaauac uccagcgacg      300

ccaaggaguu cuacggaaac aaaacccgaa ugagcuucau aauggacgaa aucggucgcc      360

gcgcgcccca auacacggaa aucgaccaua aaggaauccc uaccuuaguc gaggucguaa      420

gagcggguuu cuaccuagga uuccacaaca aagagcuaaa cgagaucaac aaacgcuccu      480

ucaaagaacg cgugaucccc ucuauccuag ccauccagaa aaacccaaau uucaaacucg      540

gcaccgaagu acaagauaaa auaguaagcg ccaccggacu ccucgcuggc aacgaaaccg      600

cacccccaga aguagugaau aacuucacac ccauccucca agauugcauc aaaaauauag      660

accgauacgc ccuggacgau uuaaaaagca aagcacucuu caacguacuc gcugcaccca      720

cauacgacau cacagaguac uugagggcaa cgaaagagaa acccgaaaac acccccuggu      780

acggaaaaau agacggcuuc aucaacgaac uaaagaaauu ggcgcuauau gggaaaauca      840

acgacaacaa caguuggaua aucgacaacg gcaucuauca cauagcaccc cucggcaaac      900

uccauagcaa caacaaaaua ggcauagaaa cacuaacuga agucaugaaa guauaccccu      960

aucucagcau gcaacaccua caauccgccg accaaaucaa acgccacuac gacagcaaag     1020

acgcagaagg caacaaaaua ccccucgaca aguucaagaa agaaggaaaa gagaaauacu     1080

gccccaaaac cuacaccuuc gacgacggca aaguaaucau caaggccgga gcacgaguag     1140

aagaagagaa aguaaaacga cucuacuggg cgagcaaaga agucaauagc caauucuucc     1200

gcguuuacgg uaucgauaaa ccgcuugaag aaggcaaccc agaugacauc cuaacgaugg     1260

uuaucuauaa cagucccgaa gaauacaaac ucaacagcgu ccuuuauggg uacgacacca     1320

auaacggcgg gauguacauc gaacccgagg ggaccuucuu cacauacgaa cgagaagccc     1380

aagaauccac cuacacacua gaagaacucu uccgccacga auacacccac uaucuucagg     1440

gcagauacgc cguaccagga caauggggga ggaccaaauu auacgacaac gaccgacuca     1500

caugguacga agaaggcggc gccgaguuau ucgcuggaag uacucgaacc uccggcaucc     1560

uuccccgaaa aagcauaguc ucgaacaucc acaacacaac ccguaacaau cgcuacaaac     1620

uauccgauac aguccacagc aaauauggag cuagcuuuga guucuacaac uaugccugca     1680

uguucaugga cuacauguac aacaaggaca ugggcauccu caacaaacua aacgaccugg     1740

cgaaaaacaa cgacguagac ggcuacgaca acuacauacg cgaucuuagc ucuaacuacg     1800

cccuaaacga caaauaucaa gaccauaugc aggaacggau cgauaauuac gaaaaucuca     1860

caguacccuu cgucgccgac gacuaccuag uccggcaugc auacaaaaac ccgaaugaga     1920

uauacuccga gaucucagaa gucgcaaaac ugaaagacgc aaagucggaa guuaaaaaga     1980

gccaauacuu cagcacauuc acccuccgcg gaucuuacac cggcggggcc uccaagggga     2040

aacuugagga ccaaaaagca augaacaaau uuaucgacga cagccucaaa aagcucgaca     2100

ccuacagcug gagcggguac aaaacacuua cggcauacuu caccaauuac aaagucgacu     2160

cgagcaaucg ggucaccuac gacguggucu uccacggcua ccuaccgaac gaaggcgaca     2220

gcaaaaacuc acuaccguac ggcaaaauaa acggcacgua uaaagggacc gaaaaagaaa     2280

agaucaaguu cucaucagaa ggcuccuucg acccagacgg aaaaauagug agcuaugagu     2340

gggauuucgg cgacgggaac aaaucaaacg aagagaaccc ggagcacagc uacgacaaag     2400

ucgggaccua caccgucaaa cuaaaaguca ccgaugacaa aggcgagucc ucaguaucca     2460

cgaccacggc ugaaaucaaa gaccugagcg aaaacaagcu cccagucaua uacaugcacg     2520

ucccgaaauc cggcgcccua aaccagaaag ucgucuucua cggcaaaggc acuuacgacc     2580

cagacggcag cauagcagga uaccaauggg acuucgggga cggcuccgac uucucaucag     2640

aacagaaccc aucacacguc uacaccaaaa agggcgagua cacaguuaca cuccgcguga     2700

uggacuccuc cggacaaaug agcgagaaaa caaugaaaau aaaaauaacc gacccgguau     2760

acccaauagg cacggaaaag gaaccuaaca acagcaaaga aacagcauca ggucccauug     2820

uacccggcau cccagucuca ggaaccaucg aaaacaccuc cgaccaagac uacuucuacu     2880

ucgauguaau aacacccggc gaaguaaaaa ucgacaucaa caaacucggg uacgggggag     2940

caaccugggu cguauacgau gaaaacaaca acgcugucuc auacgcaacc gacgacggac     3000

agaaccugag cggcaaguuc aaagccgaca aaccagggag guacuacaua caccucuaca     3060

uguucaaugg uagcuacaug ccuuaccgua uaaauaucga aggaucugua ggacgauaag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  3437
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt9)

<400>  3437
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

gggugaccuu cauaagccuu cucuuccucu ucucauccgc cuacagcgua caaaacgagu      120

cgaaaagaua caccguauca uaccucaaga cccucaacua cuacgaucuc gucgaucuau      180

uagucaagac agaaaucgaa aaucuacccg accuauucca guacucaucg gacgccaaag      240

aguucuacgg caacaaaaca cgaaugagcu ucauuaugga cgaaauaggu agacgagcgc      300

cgcaguacac ggaaaucgac cacaaaggga uccccaccuu agucgaaguu guacgcgcgg      360

gcuucuaccu aggauuucac aacaaagaac uuaacgaaau caacaaacgc aguuucaaag      420

aacgcgucau ccccagcauc cuagcgaucc agaaaaaccc caauuuuaaa cucggcaccg      480

aaguacagga caagauagug ucagcaacag gccugcucgc cggaaacgaa acggccccac      540

ccgaaguagu caauaacuuc acacccauac ugcaggacug caucaaaaau aucgaccgau      600

acgcacucga cgaccucaag agcaaagccc ucuucaacgu gcucgccgcc ccaaccuacg      660

acauaaccga auacuugagg gccacaaaag aaaaacccga aaacacccca ugguacggca      720

aaauugacgg auucaucaac gagcugaaga aacucgcccu cuacgggaaa aucaaugaca      780

acaacagcug gaucaucgac aacggcaucu accacauugc cccgcuaggc aaacuacacu      840

ccaacaacaa aaucggcauc gaaacgcuca cggaagucau gaaaguauau ccauaucuau      900

ccaugcaaca ccuccaaucu gccgaccaaa ucaaacgcca cuacgacagc aaggacgcgg      960

aaggaaacaa aaucccacuc gacaaguuua agaaggaagg caaagaaaaa uacugcccua     1020

aaaccuacac guucgaugac gggaaaguaa uuaucaaagc cggcgcccga gucgaagagg     1080

aaaaggugaa acgccuauac ugggccucca aagagguuaa uucacaauuu uuccgagucu     1140

auggcaucga caaaccacuc gaggaaggua accccgacga uauccucacc augguaauau     1200

auaauucgcc cgaggaauau aaacucaaca gcgucuuaua cggcuacgac accaacaacg     1260

guggcaugua caucgagccg gaaggcaccu ucuucaccua cgagcgugaa gcccaagaau     1320

ccacguacac acuugaggaa cuauuccgac augaauacac ccacuaccug caaggccggu     1380

acgcaguacc uggccagugg ggccgcacua aacucuacga caacgaccgu cucaccuggu     1440

acgaagaagg uggagccgaa cucuucgccg gcuccacccg caccagcggc auccuacccc     1500

gaaaauccau agucucgaac auucacaaca caacccgaaa uaaccgcuac aaacucagcg     1560

acaccguaca cucaaaauac ggagccagcu ucgaguucua caacuacgcg ugcauguuca     1620

uggacuacau guacaacaaa gauaugggga uucuaaacaa acuuaacgac cucgccaaaa     1680

auaacgacgu cgacgguuac gacaacuaua uacgagaucu uucaucgaac uacgcacuaa     1740

acgacaaaua ccaggaccac augcaagaac gcaucgacaa cuacgaaaac cucaccgucc     1800

ccuucgucgc agacgauuac cucguccgac acgcauacaa gaaccccaac gaaauauacu     1860

cggagaucag cgaagucgcc aagcucaaag augcaaaauc cgaagucaaa aagucacagu     1920

acuuuagcac auucacacuc cgcgggagcu acaccggcgg cgcguccaag ggaaagcucg     1980

aagaccaaaa agccaugaac aaauuuauag acgacucccu caagaaacuc gacaccuacu     2040

cguggagcgg cuacaaaaca cuuaccgcau acuucaccaa cuacaaagua gacagcucaa     2100

aucggguaac uuacgacgua gucuuccacg gcuaccuucc caaugaagga gacagcaaga     2160

acucacuccc uuacggcaaa auaaauggaa cguacaaggg cacggaaaag gagaaaauca     2220

aauucagcuc cgaaggcucc uucgaccccg acggaaaaau aguaucauac gaaugggacu     2280

ucggcgacgg caacaagagu aacgaagaaa aucccgaaca cucauacgac aaagucggca     2340

cguacaccgu caaacuaaaa guaacagacg acaaaggcga auccucagug aguacgacca     2400

ccgcagaaau caaagacuua ucagaaaaca aacuccccgu aauauacaug cacgucccaa     2460

agagcggggc acucaaccaa aaagucgucu ucuacggcaa aggaaccuac gacccugacg     2520

gauccaucgc cggcuaccag ugggauuucg gcgacggaag cgacuucuca ucggagcaaa     2580

acccaagcca cgucuacacg aaaaagggag aauacacagu gacacuccga guaauggacu     2640

ccucagggca gauguccgag aaaaccauga aaauaaagau caccgacccu gucuacccca     2700

ucggaaccga aaaggagccu aacaauucca aagaaaccgc cagcggacca auaguacccg     2760

guauccccgu cuccggaacc aucgaaaaca cgucagacca ggacuacuuc uacuucgacg     2820

ucauaacccc gggcgaagua aaaaucgaca ucaacaaacu aggcuacggc ggagccacau     2880

gggucguaua cgacgaaaac aacaacgcgg uaucuuacgc aacagacgac ggccaaaacc     2940

uaagcggcaa guucaaagca gacaaacccg ggcgcuacua cauccaccug uacauguuca     3000

acggaagcua caugccauac agaauaaaua ucgaaggcuc cguaggacgu uaaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3438
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt9)

<400>  3438
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

gggucaccuu caucucucua cuguuccucu ucucuagcgc auauagcaug aaacggaaau      120

gucuauccaa acgccugaug cuggccauua cgauggccac caucuucacc gucaacucua      180

cccugccgau cuacgccgcc guagacaaga acaacgccac cgccgcucgc cgccgaagaa      240

agagggucca aaacgaaagc aaaagauaca caguaagcua ccuuaagaca cucaacuacu      300

acgaccucgu agaccuacuc gucaagacag aaauugagaa ccuccccgac cuauuccaau      360

acagcagcga cgccaaagag uucuacggca acaaaacccg aaugucuuuc auaauggaug      420

aaauaggacg cagagcgccc caauacacgg aaaucgauca caaaggcaua cccacccuag      480

uggaagucgu acgagcuggc uucuaucugg guuuccacaa caaagaacug aacgaaauaa      540

acaagcgcag cuucaaagaa cgcgugaucc ccucaauacu ggcuauccag aaaaauccca      600

auuucaaacu agggaccgaa guccaagaca agaucguguc cgcgacagga cuccucgccg      660

gcaacgaaac cgccccgccg gaagucguua acaacuucac gccaauacua caagacugca      720

uuaaaaacau cgaccgauac gcccuagacg aucugaaauc caaggcacua uucaacguuc      780

uggccgcacc aacauacgac aucacagagu accugcgugc cacaaaagaa aaaccagaaa      840

auacccccug guacggcaaa aucgacggau ucauuaauga guugaaaaag cuagcacucu      900

acggaaaaau caacgacaau aacagcugga ucaucgacaa cggcauuuac cacauagcgc      960

cccucggcaa acugcacucc aacaacaaaa ucgguauaga gacacucaca gaggugauga     1020

aaguuuaccc auaccuaagc augcaacacc uucaauccgc cgaccaaauc aaacgccacu     1080

acgacuccaa agacgcggaa ggcaacaaaa uaccccucga caaauuuaaa aaggagggca     1140

aagaaaaaua cugcccaaag accuacaccu ucgaugacgg caaaguaaua aucaaagcag     1200

gagccagagu cgaggaggag aaggucaaaa ggcuauacug ggcaucuaag gaagugaaca     1260

gccaauucuu ucggguauac ggaaucgaca agccccuaga agaagguaac cccgacgaca     1320

uccuuacaau gguaauauac aacagcccgg aagaguacaa acucaacagu guucuauacg     1380

gauacgauac gaacaacgga ggcauguaca ucgaaccgga gggcaccuuc uucaccuacg     1440

agcgagaggc ccaagaaagc acauacaccu uagaagaacu guuccgacac gaauacaccc     1500

auuaccucca aggcagauac gcuguccccg gccaaugggg acgcacuaaa cuauacgaua     1560

acgaccgccu aacaugguac gaagagggug gcgccgaacu cuucgccggc ucaacgagaa     1620

cgagcggaau ccugccgcgc aaaagcaucg ucagcaacau acacaacaca acgcgaaaca     1680

aucguuacaa acucucggac acgguccacu caaaauacgg cgcgucauuc gaguucuaca     1740

acuacgccug cauguucaug gauuacaugu acaauaagga caugggcauc cuaaacaaac     1800

ucaacgaccu cgcuaaaaac aacgacgucg acggcuacga caacuauauc cgagaccuaa     1860

gcucgaacua cgcacucaau gacaaauacc aagaccacau gcaagagcgc aucgacaacu     1920

acgaaaaccu aacaguaccc uucguugcgg acgacuaucu cgucaggcac gcauacaaga     1980

acccaaacga gauauacagc gaaaucagcg agguagccaa acuuaaggac gccaaauccg     2040

aagucaagaa aucgcaguac uucucaaccu ucacgcuacg uggcagcuac accgggggag     2100

caagcaaagg aaaacucgag gaccaaaaag caaugaacaa guuuauugac gacagccuaa     2160

agaaacuaga uacauauucc ugguccggcu acaaaacgcu aacggcauac uucacgaacu     2220

acaagguuga cucaaguaac cgcguaacau acgacguagu uuuccacgga uaccuaccaa     2280

augaaggcga cuccaaaaac ucgcugccau acggaaaaau caauggcaca uacaaaggga     2340

cagagaagga gaaaaucaaa uucaguucag aaggauccuu cgacccagac ggcaaaaucg     2400

uuucauauga augggauuuc ggagacggga acaaaucaaa cgaagaaaac ccugagcaca     2460

gcuacgacaa agucggcaca uauacaguaa agcucaaagu cacggacgac aagggcgaga     2520

gcagcguaag cacgaccacc gcagaaauca aggaccucuc cgaaaauaaa cucccaguca     2580

uauacaugca cguaccaaaa ucgggcgccc ucaaccagaa aguaguguuc uacggaaaag     2640

gcacauacga uccggacgga uccauagcag gcuaccaaug ggauuucgga gaugggagcg     2700

acuucucgag cgaacaaaac ccgucacacg ucuacacuaa aaagggcgag uacaccguaa     2760

cccuucgggu aauggacucc uccggacaaa ugucugagaa aaccaugaaa aucaagauaa     2820

ccgacccagu auaccccauc ggcaccgaaa aagaaccaaa caacuccaaa gaaacugccu     2880

ccggccccau cguaccggga aucccagucu ccggcaccau cgaaaacacc agcgaccaag     2940

auuacuucua cuucgacgua aucacccccg gagaagucaa aaucgacauc aacaaacugg     3000

gcuacggagg agcuaccugg guagucuacg acgaaaacaa caacgccguc aguuacgcca     3060

ccgacgacgg gcaaaaccug uccgguaaau uuaaggccga caagccaggg cgauacuaca     3120

uccaccugua uauguuuaac ggauccuaua ugcccuaccg aauaaauauc gaaggaagug     3180

uaggccgcua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  3439
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt9)

<400>  3439
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu cuucgcaugc cuccucggcg cagccuucgc caugccccuc ccuccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgaaguccu cacaccccuc aaaugguauc      180

aauccaucag accacccuac cccuccuacg gcuacgaacc caugggcggc uggcuccacc      240

accaaaucau ccccguccuc ucacaacaac acccucccac ccacacccuc caaccccacc      300

accacauccc cguagucccc gcccaacaac ccgucauccc ccaacaaccc augaugcccg      360

uccccggcca acacucaaug acccccaucc aacaccacca acccaaccuc ccaccacccg      420

cccaacaacc cuaccaaccc caacccgucc aaccccaacc ccaccaaccc augcaacccc      480

aaccacccgu acaccccaug caaccccucc caccccaacc accccuaccu cccauguucc      540

ccaugcaacc ccucccaccc augcuccccg accucacccu cgaagccugg cccuccaccg      600

acaaaaccaa acgcgaagaa guagacuaag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  3440
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt9)

<400>  3440
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

uaccccccca cccaggccac cccggcuaca uaaacuucuc cuacgaagua cucacacccc      120

uaaaauggua ccaauccauc cgaccccccu accccucaua cggcuacgaa cccaugggcg      180

gcugguaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  3441
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt9)

<400>  3441
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca uaaacuucuc auacgaaguc cucacccccc      120

uaaaauggua ccaauccauc cgcccccccc ccaugcuccc cgaccucaca cucgaagccu      180

ggcccucaac cgacaaaaca aaacgcgaag aagucgacua aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  3442
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt9)

<400>  3442
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

uaauggcccc ccgaacccuc guccuccuac ucucaggagc ccucgcccuc acccaaaccu      120

gggccaugcc ccucccaccc cacccaggcc accccggaua caucaacuuc uccuacgaag      180

uacucacccc ccuaaaaugg uaccaaucca uccgcccccc cuaccccuca uacggcuacg      240

aacccauggg cggaugguaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  3443
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt9)

<400>  3443
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

uaauggcacc ccgcacccuc guccuacucc uauccggcgc ccucgcccuc acacaaaccu      120

gggccaugcc ccucccaccc caccccggcc accccggcua cauaaacuuc uccuacgaag      180

uccucacccc acucaaaugg uaccaaucca uccgcccacc acccaugcua cccgaccuca      240

cacucgaagc cuggcccucc accgacaaaa caaaacgcga agaagucgac uaaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  3444
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt9)

<400>  3444
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cuagucggcg ccgccuucgc caugccccuc ccaccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgaaguccu aacaccccua aaaugguacc      180

aauccaugau ccgcccaccc uacuccuccu acggcuacga acccaugggc ggauggcucc      240

accaccaaau cauccccguc gucucccaac aacacccccu cacccacacc cuccaaucac      300

accaccacau ccccguaguc cccgcccaac aaccccgcgu acgacaacaa gcccucaugc      360

ccguccccgg ccaacaaucc augaccccca cccaacacca ccaacccaac cucccacucc      420

ccgcacaaca acccuuccaa ccccaacccg uccaacccca accccaccaa ccaaugcaac      480

cccaaccacc cguccaaccc augcaacccc ucuuacccca accaccccua ccacccaugu      540

ucccccuccg cccccuacca cccauccucc ccgaccucca ccucgaagcc uggcccgcca      600

ccgacaaaac aaaacaagaa gaagucgacu aaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  3445
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt9)

<400>  3445
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

uaccacccca cccaggccac cccggcuaca ucaacuucuc auacgaaguc cucacccccc      120

uaaaauggua ccaaucaaug auccgccccc cauacucauc cuacggcuac gaacccaugg      180

gcggcuggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3446
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt9)

<400>  3446
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca cccaggccac cccggcuaca ucaacuucuc cuacgaagua cucacccccc      120

uaaaauggua ccaauccaug auccgccccc cccccauacu ccccgaccuc caccucgaag      180

ccuggcccgc cacagacaaa accaaacaag aagaaguaga cuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3447
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt9)

<400>  3447
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

ucauggcacc ccgcacccuc guccuccucc ucuccggcgc ccucgcccua acccaaaccu      120

gggcaaugcc acuaccccca caccccggcc accccggcua caucaacuuc ucauacgaag      180

uccuaacacc ccucaaaugg uaccaaucaa ugauccgccc acccuacucc uccuacggcu      240

acgaacccau gggcggcugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3448
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt9)

<400>  3448
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcacc ccgaacacuc guccuccucc ucuccggcgc ccucgcccuc acacaaacau      120

gggccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacacc ccuaaaaugg uaccaaucca ugauccgccc acccccaaua cuccccgacc      240

uacaccucga agccuggccc gccaccgaca aaaccaaaca agaagaaguc gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3449
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt9)

<400>  3449
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauacu cuucgccugc cuccucggcg ccgccuucuc caugccccua ccaccccacc      120

ccggacaccc cggcuacauc aacuucuccu acgaaguccu aacaccccuc aaaugguacc      180

aaaauaugau acgccacccc uacacauccu acggcuacga acccaugggc ggauggcucc      240

accaccaaau cauccccguc gucucacaac aaaccccaca aucccacgcc cuccaacccc      300

accaccacau ccccaugguc cccgcccaac aacccggcau cccccaacaa cccaugaugc      360

cccuccccgg ccaacacucc augaccccca cccaacacca ccaacccaac cuaccccuac      420

ccgcccaaca acccuuccaa ccccaacccg uacaacccca accccaccaa ccccuucaac      480

cccaaucucc caugcacccc auccaacccc uccuccccca accaccccuu ccacccaugu      540

ucucaaugca aucacuccuc cccgaccucc cccucgaagc cuggcccgcc accgacaaaa      600

ccaaacgaga agaagucgac uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3450
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt9)

<400>  3450
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

uaccacccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc cuaacacccc      120

uaaaauggua ccaaaacaug auccgccacc cauacaccuc auacggcuac gaaccaaugg      180

gcggcuggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3451
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt9)

<400>  3451
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccacccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc cuaacacccc      120

ucaaauggua ccaaaacaug auccgacacc ccucccuacu ccccgaccuc ccccuagaag      180

cauggcccgc caccgacaaa accaaacgcg aagaagucga cuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3452
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt9)

<400>  3452
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcacc ccgcacccua guccuccucc ucucaggcgc ccucgcacuc acccaaacau      120

gggccaugcc ccuaccccca caccccggcc acccaggcua caucaacuuc ucauacgaag      180

uccucacccc acuaaaaugg uaccaaaaca ugauacgcca ccccuacacc ucauacggau      240

acgaacccau gggcggcugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3453
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt9)

<400>  3453
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcacc ccgcacucuc guccuccuac ucuccggcgc ccuagcccuc acccaaaccu      120

gggccaugcc ccuaccccca caccccggcc accccggcua caucaacuuc ucauacgaag      180

uccucacccc acuaaaaugg uaccaaaaca ugauccgcca ucccucacuc cuccccgacc      240

ucccccuaga agccuggccc gccacagaca aaaccaaacg cgaagaaguc gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3454
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt9)

<400>  3454
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauacu cuucgccugc cuccucggcg cagccuucuc caugccccuc ccaccccacc      120

ccggccaccc cggcuacauc aacuucucuu acauccgcca ccccuacacc uccuacggcu      180

acgaacccau gggcggcugg cuacaccacc aaaucauccc cgucguaucc caacaaaccc      240

cacaaucaca cgcucuccaa ccccaccacc acauccccau gguccccgcc caacaacccg      300

gcauccccca acaacccaug augccccucc ccggccaaca cuccaugacc cccacccaac      360

accaccaacc caaccucccc cucccagccc aacaacccuu ccaaccccaa cccguccaac      420

cccaaccaca ccaaccacua caaccacaau cccccaugca ccccauccaa ccacuccucc      480

cccaaccacc ccucccaccc auguucucaa ugcaaucccu ccuacccgac cuuccccuug      540

aagccuggcc cgccaccgac aaaaccaaac gagaagaagu cgacuaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  3455
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt9)

<400>  3455
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggaucuu cuucgcaugc cuccuaggcg ccucccucgc caugccccuc ccaccccacc      120

ccggacaccc cggcuacauc aacuucuccu acgaaguccu caccccacua aaaugguacc      180

aaaacaugau ccgccacccc uacaccuccu acggauacga acccauggga ggcuggcucc      240

accaccaaau cauccccguc gucucacaac aaacacccca aucccacgca cuccaacccc      300

accaccacau ccccaugguc cccgcccaac aacccggaau cccccaacaa cccaugaugc      360

cccuccccgg acaacacucc augaccccca cccaacacca ccaaccaaac cucccccucc      420

ccgcccaaca acccuuccaa ccacaacccg uccaacccca accccaccaa ccacuccaac      480

cccaaucccc caugcacccc auccaaccac uccuccccca accaccccuc ccacccaugu      540

ucucaaugca aucccuccuu cccgaccucc cccucgaagc cuggcccgcc accgacaaaa      600

ccaaacgcga agaaguagau uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3456
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt9)

<400>  3456
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauacu cuucgccugc cuacucggcg ccgcauucuc aaugccccuc cccccccacc      120

ccggccaccc cggcuacaua aacuucuccu acgaaguccu caccccccuc aaaugguacc      180

aaaacaugau uagacaccca ucccuccucc ccgaccuccc ccucgaagca uggcccgcaa      240

ccgacaaaac caaacgcgaa gaagucgacu aaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  3457
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt9)

<400>  3457
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

cauggauccu cuucgccugc cuacucggag ccgcuuuuuc caugccccuc ccuccccacc      120

ccggccaccc cggcuacaua aacuucuccu acgaagaccu cuaccucgaa gccauccgca      180

ucgaccgcac cgccuucguc cucacacccc uuaaauggua ccaaaacaug auccgccacc      240

ccuacaccuc cuacggcuac gaacccaugg gcgguuggcu ccaccaccaa aucauccccg      300

uagucucaca acaaacccca caaucccacg cccuccaacc ccaccaccac auaccaaugg      360

uccccgccca acaaccaggc aucccccaac aacccaugau gccccucccc ggccaacacu      420

ccaugacccc aacccaacac caccaaccca accucccccu ccccgcccaa caacccuucc      480

aaccccaacc cguccaaccc caaccccacc aaccccucca accccaaucc cccaugcacc      540

ccauccaacc ucuccucccc caacccccac ucccaccaau guucucaaug caaucacucc      600

uccccgacuu accccuagaa gccuggcccg ccaccgacaa aaccaaacga gaagaaguag      660

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  3458
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt9)

<400>  3458
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cuccucggcg ccgccuucuc caugccccuc ccaccccacc      120

ccggccaccc cggcuacauc aacuucucau augaaguccu cacaccccuc aaaugguacc      180

aaaacaugau ccgccacccc acaccccaau cccacgcccu ccaaccacac caccacaucc      240

ccaugguccc cgcccaacaa ccaggcaucc cacaacaacc caugaugccc cuaccaggcc      300

aacacuccau gacccccacc caacaccacc aacccaaccu accccucccc gcacaacaac      360

ccuuccaacc acaacccguc caaccccaac cccaccaacc ccuacaaccc caauccccca      420

ugcacccaau ccaaccccuc cucccccaac caccccuccc acccauguuc uccaugcaau      480

cacuccuccc cgaccucccc cuagaagccu ggcccgcaac cgacaaaacc aaacgcgaag      540

aagucgacua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  3459
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt9)

<400>  3459
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccacccca ccccggccac cccggcuaca ucaacuucuc cuacgaagua cucaccccuc      120

ucaaauggua ccaaaacaug auccgacacc ccuacaccuc cuacggcuac gaacccaugg      180

gcggcuggcu ccaccaccaa aucauccccg ucgucuccca acaaacaccc caaucccacg      240

cacuacaacc ccaccaccac auccccaugg uccccgccca acaacccggc aucccccaac      300

aacccaugau gccacucccc ggccaacacu ccaugacccc cacccaacac caccaaccca      360

accucccccu acccgcccaa caacccuucc aaccccaacc cguccaacca caaccucacc      420

aaccacucca accccaauca cccaugcacc ccauccaacc acuccuaccc caacccccac      480

ucccacccau guucuccaug caaucacucc uccccgaccu cccccuagaa gccuggcccg      540

ccaccgacaa aaccaaacgc gaagaagucg acuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  3460
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt9)

<400>  3460
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

gagucgcccg gcuaccccua cuccuaggac uccuccuacu accacgcccu ggacgacccc      120

uagaccuggc cgacuacacg uacgaccuag ccgaagaaga cgacuccgaa ccccucaacu      180

acaaagaccc cugcaaggcc gccgccuucc uaggcgacau agcccuagac gaagaagacc      240

uccgagccuu ccaaguccaa caagcggucg accugcgccg acacacggcc aggaaaucau      300

ccauaaaagc cgcuguaccg ggaaacacau caacccccuc augccaaucg acaaacggac      360

aaccacaaag gggcgcaugc ggaagauggc gcgggcgauc acgcucacgc cgcgcagcca      420

caagccgccc ggagcgagug uggcccgacg ggguaauacc cuucgucaua gggggaaacu      480

ucacuggauc acaacgggca gucuuuagac aagcaaugag acacugggaa aagcauaccu      540

gcgucacauu ccuagaacgg accgacgaag auucauacau cguauucacc uaccgcccau      600

gcggauguug cucauacgua ggccgaagag gcggcggccc ccaagcgaua ucgauaggca      660

agaacugcga caaauucggg auaguuguac acgaacuagg acacgucgua ggcuucuggc      720

acgaacacac cagacccgac cgggaccggc acguauccau aguccgcgaa aacauccaac      780

ccggacaaga auacaacuuc cuaaaaaugg aaccacaaga agucgaaucg cuaggcgaaa      840

ccuaugacuu cgauuccauc augcacuaug cucgcaacac cuucucacga ggcaucuucc      900

ucgacaccau cguccccaaa uacgaaguua acggagucaa accacccaua ggacaacgca      960

cgcgacucuc aaaaggcgau aucgcucaag cacgcaaacu cuacaagugu cccgccugcg     1020

gcgaaacgcu ccaggacucg acaggcaacu ucucaucccc cgaauacccg aacggauaca     1080

gcgcacacau gcacuguguc uggcgaaucu caguaacacc aggcgagaaa aucauccuua     1140

acuucacauc ccucgaccug uacagauccc gccucugcug guacgauuac gucgaaguca     1200

gagacggguu cuggcgaaaa gcaccgcucc gaggccgauu cuguggaucc aaacugccag     1260

aacccauagu cuccacagac ucucgacucu ggguugaguu cagaagcucu aguaacuggg     1320

ucggcaaagg cuucuucgcc gucuacgaag caaucugcgg aggagacgua aagaaagauu     1380

acggccacau acaguccccc aacuaccccg acgacuaccg gcccaguaaa guauguaucu     1440

ggagaaucca gguaagcgaa ggcuuccaug uugggcucac cuuucagagc uucgaaauag     1500

aacgccacga cucaugcgcu uaugacuauc ucgaaguacg cgacggccac uccgaaucaa     1560

gcacacucau aggcagauac ugcggauacg aaaaacccga ugacaucaaa uccacgucca     1620

gccgccuaug gcucaaauuc gucucagaug gaagcauaaa caaagccgga uuugcuguua     1680

acuucuucaa ggaaguagac gagugcuccc gacccaaccg cggcgggugc gaacaacgcu     1740

gccucaacac acucgguucc uacaaaugca gcugcgaccc aggcuacgaa cuagccccug     1800

auaagcgucg cugcgaagca gccugcggug gguuccucac aaaacuaaac ggauccauaa     1860

caagcccugg cuggccaaaa gaauaucccc cuaacaagaa cugcaucugg caacuggugg     1920

cgcccacaca auaccgaaua agccuacaau uugacuucuu cgagacagaa ggaaaugacg     1980

ugugcaagua cgacuucgua gaaguccgcu ccggguuaac cgccgacucc aagcugcaug     2040

ggaaauucug cggauccgaa aaaccagaag ugauuacgag ccaauacaac aacaugcgag     2100

ucgaguucaa gucagacaac acagucucca agaaaggcuu uaaagcucac uucuucucag     2160

acaaagacga gugcucaaaa gacaauggag ggugucaaca agacugcguu aacacauucg     2220

gguccuacga augccaaugc cgcucugggu ucguacuuca cgauaacaag cacgacugca     2280

aagaagccgg augcgaccac aaggugacaa gcaccuccgg caccauaacg ucccccaacu     2340

ggccagauaa auaccccuca aagaaagaau gcacgugggc caucaguagc acucccggcc     2400

acagagucaa acucacauuc auggaaaugg acaucgaaag ccagccggag ugcgcguacg     2460

accaccucga aguguucgac ggacgcgacg cgaaggcucc agugcucggc cgauucugcg     2520

gauccaagaa gccagaacca gucuuagcaa cuggaagccg aauguuccua cgauucuacu     2580

ccgacaauuc cguucaacga aaaggcuucc aagccuccca cgccaccgaa ugcggcggac     2640

aaguccgagc ggacguaaaa accaaagacc ucuacagcca cgcgcaauuc ggggacaaca     2700

acuacccagg uggcguagac ugcgaauggg uaauagucgc agaagaaggc uacggagucg     2760

agcuaguauu ccagaccuuc gaaguugaag aagaaacaga cugcggcuac gacuacaugg     2820

aacuauucga cgguuacgac uccaccgcac cccggcucgg acgguacugc ggcuccggcc     2880

caccagaaga aguauacuca gcaggagaca gcguccucgu caaauuccac uccgaugaua     2940

ccauaacaaa gaaaggguuu caccuacgcu acacgagcac caaauuccaa gacacucuac     3000

acagccgcaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  3461
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt9)

<400>  3461
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguag       60

ccggcacccg augccuacuc gcccuccuuc ucccccaagu ccuccuaggc ggcgccgccg      120

gccugguccc agaacuaggc cgccgcaaau ucgcagccgc auccuccgga cgcccaucau      180

cacagcccuc cgacgaaguc cucuccgagu ucgaacucag acuacuaucg auguucggcc      240

uuaaacaacg ccccacccca ucccgugacg ccguaguccc accauacaug cucgaccuau      300

accgccgcca cuccgggcaa cccggaucac cagcacccga ccaccgccuc gaacgcgccg      360

caucccgcgc caacacaguc cgcuccuucc accacgaaga aucccucgaa gaacuccccg      420

aaacaucagg caaaacaacc cgccgauucu ucuucaaccu cuccuccaua cccacagaag      480

aguucaucac cuccgcagaa uuacaagucu uccgcgaaca aaugcaagac gcacucggca      540

acaacuccuc cuuccaccac agaaucaaca ucuacgaaau caucaaaccc gcaaccgcca      600

acagcaaauu cccaguaacc cgacuccuug acacacgacu cgucaaccaa aacgccucca      660

gaugggaauc auucgacguc acaccagcag ucaugcgcug gaccgcccaa ggccacgcaa      720

accauggauu cgugguagaa gucgcccacc uagaagaaaa acaaggaguc uccaaacgcc      780

acguccgcau cucacgcucc cuccaccaag acgaacacuc auggucacaa auccgacccc      840

uccuaguaac auucggacac gacggcaaag gccacccccu acauaaacgc gaaaaacgac      900

aagccaaaca uaagcaacga aaacgccuca aaucaagcug uaaacgucau ccacucuacg      960

ucgacuucuc ugacgucggc uggaacgacu ggaucguagc accacccggc uaccacgccu     1020

uuuacugcca cggagaaugc cccuuccccc ucgccgacca ccuaaauucc accaaccacg     1080

caauagucca aacccuaguu aacuccguca acuccaaaau cccaaaagca ugcugcguuc     1140

ccacagaacu cucagcaauc uccaugcucu accuugacga aaacgaaaaa gucguccuga     1200

aaaacuacca agacaugguc gucgaaggcu gcggcugccg auaaggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  3462
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt9)

<400>  3462
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauac       60

ccggcaaccg uaugcucaug gucguccucc ucugccaagu acuccucggc ggagccucac      120

acgcaucucu cauacccgaa acuggcaaaa aaaaagucgc cgaaauccaa ggccacgcag      180

gaggacgccg cucaggucaa ucccacgaac uccuacgcga cuucgaagcc acccuacuac      240

aaauguucgg ccuccgacgc cgaccccagc ccuccaaauc cgccgucaua cccgacuaca      300

ugcgcgaccu cuaccgacuu caauccggcg aagaagaaga agaacaaaua cacagcaccg      360

gccucgaaua ccccgaacgu ccagccuccc gcgccaacac cguccgcucu uuccaccacg      420

aagaacaccu cgaaaacauc cccggcacau ccgaaaacuc cgccuuccga uuccucuuca      480

accuauccuc aauccccgaa aacgaaguca uauccuccgc cgaacuccgu cucuuccgcg      540

aacaaguaga ccaaggcccc gauugggaac gcggcuucca ccgcaucaau aucuacgaag      600

ucaugaaacc accagccgaa gucguacccg gacaccucau cacacgcuua cuagacaccc      660

gccucgucca ccacaacgua acacgcuggg aaaccuucga cgucucccca gcuguucucc      720

gauggacacg cgaaaaacaa cccaacuacg gccucgccau cgaagucacc caccuccacc      780

aaacccgaac ccaccaaggc caacacguca gaaucucccg cucucucccc caaggcucag      840

gcaacugggc ccaacuacgc ccccuacuug ucaccuucgg ccacgacgga cgaggccacg      900

cacuaacgcg acgccgccgc gccaaacgcu cacccaaaca ccacucucag cgcgccagaa      960

aaaaaaacaa aaauugccgc cgacacucac uguacgucga cuucagcgac gucggcugga     1020

augacuggau cgucgccccc cccggcuacc aagcauucua cugccacggc gacugcccau     1080

ucccacuagc ugaccaccuc aacucgacca accacgcaau uguacaaacc cucgucaauu     1140

ccgucaacag cuccauccca aaagcaugcu gcgugcccac cgaacucucc gcuaucucca     1200

ugcucuaccu cgacgaauac gacaaagucg uacucaaaaa cuaccaagaa auggucgucg     1260

aaggaugcgg cugccgcuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  3463
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt9)

<400>  3463
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gucuaggccg ccgcgcacag uggcucugcu gguggugggg acuacucugc uccugcugcg      120

gcccuccccc cuuacgucca cccuuaccag cagccgccgc cgcggcagca ggaggccaac      180

uacucggcga cgguggcucc cccggacgaa cggaacaacc cccccccuca ccccaauccu      240

caagcggcuu ccucuaccgc cgccucaaaa cccaagaaaa acgagaaaug caaaaagaaa      300

uacuauccgu ccuaggccuu ccacaccggc cccgcccacu ccacggccug caacaacccc      360

agccacccgc ccuccgccaa caagaagaac aacaacaaca acaacaacuc ccccggggug      420

aacccccucc aggccgccua aaaucugccc cucucuucau gcucgaccuc uacaaugccc      480

uauccgccga uaacgacgaa gauggagcgu cagaaggaga acgccaacaa ucauggcccc      540

acgaagccgc cuccucaucc caacgccgac aacccccgcc cggcgccgcc cacccccuaa      600

accguaaauc ccugcucgcc cccggcucag gcagcggugg ugcaucccca cucaccucgg      660

cccaagacuc cgcauuccua aacgacgcag acauggucau gagcuucguc aaccuagucg      720

aauacgacaa agaauucucc ccacgccaac gacaccauaa agaauucaaa uucaaccucu      780

cacagauacc cgaaggagaa gucgucaccg ccgcagaauu ccgaaucuac aaagacugcg      840

uaauggguag cuucaaaaac caaacauucc uaaucucuau auaccaagua cuccaagaac      900

accaacaccg ugacagugac cuauuccucc ucgacacccg agucguuugg gccucagaag      960

aaggcuggcu cgaauucgac aucacagcaa ccagcaaccu auggguagua acaccgcaac     1020

acaacauggg ccuacaacua uccguaguca cccgagacgg aguacacguu cacccgcgcg     1080

cagccggccu cguaggacgc gacggccccu acgacaaaca gcccuucaug gucgccuucu     1140

ucaaagucuc cgaaguacac guccgcacca cccgcuccgc cuccucucga cgccgccaac     1200

aaucccgaaa ccgauccacc caaucccaag acgucgcccg cguuuccucu gccucagacu     1260

acaauuccuc agaacucaaa accgccugcc gaaaacacga acuauaugua ucauuccaag     1320

accuuggcug gcaagacugg aucaucgccc ccaaaggcua cgcagccaac uacugcgacg     1380

gcgaaugcuc cuucccacua aacgcccaca ugaacgccac caaccacgcc aucguccaaa     1440

cacucgugca ccuuaugaac cccgaauacg uacccaaacc augcugcgcc cccaccaaac     1500

uaaacgccau cuccguacuc uacuucgaug acaacuccaa cgucauacua aaaaaauacc     1560

guaacauggu aguacgcgcc ugcgguugcc acugaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  3464
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt9)

<400>  3464
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

ugcguucacu acgagcagcc gccccacacu cauucgucgc ccucugggcu ccccuuuuuc      120

uccuacgcuc ugcccucgcc gacuucuccc uagacaacga aguacacagc ucauucaucc      180

accgccgucu ccgcucucaa gaaagacgcg aaaugcaacg ugaaauccuc uccauccucg      240

gccuccccca ccgaccccgc ccccaccuac aaggcaaaca caacuccgcc cccauguuca      300

ugcucgaccu cuacaacgcc auggccguag aagaaggagg aggacccggu ggccaaggcu      360

ucuccuaccc cuacaaagcc gucuuuucca cccaaggucc cccgcucgca ucacuccaag      420

acucccacuu ccucaccgac gccgacaugg ucaugucauu cgucaaccuu gucgaacacg      480

acaaagaguu cuuccacccc cgcuaccacc aucgcgaguu ccgcuucgac cucagcaaaa      540

uucccgaagg cgaagccguc accgccgccg aguuccgaau cuacaaagac uacauccgug      600

aacgcuucga caacgaaacu uuccgcaucu cagucuacca aguccuccaa gaacaccuag      660

gccgcgaauc agaccucuuu cuccucgacu cacgaacccu cugggccuca gaagaaggau      720

ggcucgucuu cgacaucaca gccacaucca accacugggu cgucaacccu cgccacaacc      780

uuggacucca acuguccguc gaaacccucg acggccaauc cauaaacccc aaacucgccg      840

gccucauagg ccgacacgga ccccaaaaca aacaaccauu cauggucgca uuuuucaaag      900

caaccgaagu ccacuuuaga uccauccguu ccaccggauc aaaacaacgc ucccaaaacc      960

gcuccaaaac ccccaaaaac caagaagccc uccgcauggc caacguagca gaaaacuccu     1020

ccagcgacca acgccaagcc ugcaaaaagc acgaacucua cguaucauuu cgagaccucg     1080

gcuggcaaga cuggauaauc gccccagaag gcuacgccgc auacuacugc gaaggagaau     1140

gcgccuuccc ccuaaauucc uacaugaacg ccaccaacca cgccaucguc caaacccucg     1200

uccacuucau caaccccgaa acugucccaa aacccugcug cgcccccaca caacuaaacg     1260

ccaucucagu ccucuacuuu gacgacucau cuaacguaau ccuaaagaaa uaucgcaaca     1320

ugguaguccg cgccugcggu ugccacuagg gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  3465
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt9)

<400>  3465
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaag       60

ccuccgccgc ccuccuaugc cuccuccuca ccgccgccgc auucuccccc caaggccucg      120

cccaaccagu cggcauaaac accuccacca ccugcugcua ccgauucauc aacaaaaaaa      180

ucccaaaaca acgacucgaa uccuaccgcc gcaccaccuc cucccacugc ccccgagaag      240

ccgucaucuu caaaaccaaa cucgacaaag aaaucugcgc cgacccaacc caaaaauggg      300

uccaagacuu caugaaacac cuagacaaaa aaacccaaac cccaaaacuc uaaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  3466
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt9)

<400>  3466
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcucu       60

uaacccuuau cauacuucuu cccgucguca gcaaguucag cuuugucuca cucagugcac      120

cccaacacug gagcugcccc gaaggaacac uugccggcaa cggcaauagc acaugcguug      180

ggccggcucc cuuccuaaua uucagccacg gaaacagcau auuccgaauc gacacagagg      240

gaaccaacua cgaacagcug guagucgacg cuggcguaag cgucaucaug gacuuccacu      300

acaacgagaa gcgaaucuac uggguagauc ucgaacgcca acuacugcaa cggguauucu      360

ugaacggcuc gcgacaggag cgcgucugca auaucgaaaa gaacgucuca ggaauggcua      420

ucaacuggau uaaugaagag gugauaugga gcaaccaaca ggagggaauc auaaccguca      480

cagacaugaa ggguaacaac ucccacaucc uucucagcgc gcucaaauac ccugcaaaug      540

ucgccgugga uccugucgaa cguuuuauau ucuggucaag ugaaguagcc ggcucccucu      600

acagagccga ccucgacggu guagggguca aggcacuacu cgaaacgucc gagaaaauaa      660

cagcaguauc gcuggacgua cucgacaaac gccuauucug gauucaguac aaccgagaag      720

gcagcaacuc cuuaaucugc aguugcgacu acgacggagg uagcgugcau auaaguaaac      780

acccaacgca gcacaaccua uuugccaugu cacuguucgg ggaccgcauc uucuacagca      840

ccuggaaaau gaaaacaaua uggaucgcaa acaaacacac cggcaaggau augguccgca      900

ucaaccuaca cucuucauuc guaccccuag gggagcucaa aguagugcac ccucucgccc      960

aaccaaaagc agaggaugau accugggaac ccgaacaaaa gcugugcaaa cuccgaaagg     1020

gcaacugcuc gagcaccguc ugcggacaag accugcaaag ccaccucugc augugugcgg     1080

aaggauacgc acucucacga gaccggaagu acugcgagga cgucaacgaa ugcgccuucu     1140

ggaaccacgg augcacucuu ggauguaaga acaccccagg auccuauuac uguaccugcc     1200

cagucggauu cguacuacua ccagacggaa aacgaugcca ccaacuggua uccugccccc     1260

gaaacguauc cgaaugcucc cacgauugcg uccuaaccuc agaggggccc cucugcuucu     1320

gcccagaggg auccguguua gaacgcgacg gcaagacuug cagcggcugc agcagcccag     1380

acaacggcgg gugcagccaa cuaugcguac cacuaucacc aguuucaugg gaaugcgacu     1440

gcuucccggg uuacgaccuc cagcucgacg aaaaaucaug ugcggccagc ggaccacagc     1500

ccuuccuccu auucgccaau ucacaagaca uccggcacau gcacuucgac ggcaccgacu     1560

acgguacccu acugagccaa caaaugggua ugguguacgc gcucgaccac gacccaguag     1620

aaaacaaaau auacuucgcc cacacagccc ucaaguggau cgaacgagcc aacauggaug     1680

gaucacaacg cgagcggcua auagaggaag guguggacgu gccagaaggc cuggccguag     1740

acuggauagg ccgcagauuc uauuggacag acagagguaa aucacucauc ggacgaucag     1800

accucaacgg caaaaggucc aaaaucauca cuaaagagaa cauaucacaa ccacgcggca     1860

uagccgucca ccccauggcc aaacgccucu ucuggaccga cacgggcauc aacccaagaa     1920

uagaguccag cagccuccag ggccuaggaa gacuuguaau cgcaucgucc gaucucauuu     1980

ggcccagcgg gaucacaauc gauuuccuaa cugacaaacu cuacuggugc gacgccaaac     2040

aaaguguaau cgaaauggca aaccucgacg gaucgaaacg acggcgccuc acccaaaacg     2100

auguuggcca ucccuucgca guagcagucu uugaggacua cgucugguuc agcgacuggg     2160

ccaugcccuc cguaaugcgg guuaacaaac gcaccggcaa agaccgaguc cgacuacagg     2220

guuccaugcu uaaaccgagc ucccuaguug uaguacaccc acuagcaaaa cccggggccg     2280

accccugcuu auaucaaaac ggaggaugcg aacacaucug caagaaacgc cucggcaccg     2340

caugguguag cugccgagaa ggauuuauga aagccuccga cggcaaaacc ugucuggccc     2400

uagauggcca ccaacuccuu gcgggcggcg aaguagaccu uaaaaaccaa gugaccccgc     2460

uagacauacu cucaaaaacg cgcgucucag aagacaacau cacagaaagc caacacaugc     2520

ucguagcaga aaucauggua agcgaccaag acgacugcgc acccguagga ugcagcaugu     2580

augcacggug cauaagcgaa ggagaagacg cgaccugcca augccuaaaa ggauucgccg     2640

gagacgguaa gcucugcuca gauauugacg aaugcgaaau gggaguaccc guguguccac     2700

ccgccagcuc aaagugcauc aacacugaag gaggcuacgu cugcagaugc agcgagggcu     2760

aucaaggcga cggcauccau ugccuagaua uagacgagug ccagcuaggc gagcacucgu     2820

gcggcgagaa cgcgucgugc acaaacacgg aagguggcua uacaugcaug ugcgccggaa     2880

gacucagcga accgggucua auuugccccg acagcacccc accuccacac cuucgcgaag     2940

acgaccacca cuacuccguc cgcaacucgg acucagaaug cccccucagu caugauggcu     3000

acugcuugca ugacggcguu uguauguaua ucgaagcccu agacaaguac gcaugcaacu     3060

gcgucguagg uuacaucgga gagcgcugcc aauaucgcga ccuaaaaugg ugggaacuca     3120

gacacgcagg ucacggucag caacaaaagg uuaucgucgu agccguuugu gucguggucc     3180

uagucaugcu ccuucuccua ucgcucuggg gcgcccacua cuacagaacc caaaaacucc     3240

uauccaaaaa cccgaaaaau cccuacgaag aaucgaguag ggacguacgu ucgcgacgac     3300

ccgcagacac ggaagacggc augaguucgu gcccccaacc augguucgua guuauuaagg     3360

aacaucaaga uuugaaaaac ggcggacagc cagucgccgg agaggacggc caagcagcag     3420

auggauccau gcaacccaca ucauggagac aagaacccca acuaugcgga augggaacgg     3480

aacaaggcug cuggauucca gucaguuccg acaaaggcuc augcccacaa guaauggaac     3540

gaucguucca caugccaucc uacggaaccc aaacacucga aggcggugua gaaaagccac     3600

acagccuccu cucggcaaac ccccuauggc agcagcgcgc acuagacccu ccccaucaaa     3660

uggagcugac ccaauaggga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  3467
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt9)

<400>  3467
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

ccggcagacg cauggaaaug cuaugcgccg gccgaguccc cgcacuccua cucugccucg      120

gcuuccaccu ccuacaagcc guccuaucca ccacagucau cccaucaugc aucccaggcg      180

aaagcucuga caacugcacc gcccuagucc aaaccgaaga caacccccgc gucgcccaag      240

ucuccaucac aaaaugcuca uccgacauga acggcuacug ccuacacggc caaugcaucu      300

accucgucga caugucccaa aacuacugca gaugcgaagu cggcuacacc ggaguccgcu      360

gcgaacacuu cuuccucaca guacaccaac cucucuccaa agaauacguc gcccucaccg      420

ucauacucau uauccucuuc cucaucaccg uagucggcuc cacauacuac uucugccgcu      480

gguaccgcaa ccgcaaaucc aaagaaccca aaaaagaaua cgaacgcguc accuccggcg      540

accccgaacu cccccaagua uaaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  3468
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt9)

<400>  3468
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

aaggcgaaau cacaaccuuc accgcccuca ccgaaaaauu caaccucccc cccggcaacu      120

acaaaaaacc caaacuccua uacugcucca acggcggaca cuuccuccgu auacuccccg      180

acggcacagu cgacggcacc cgagaccgcu cugaccaaca cauccaacuc caacucucag      240

ccgaaucagu cggcgaaguc uacauaaaau ccaccgaaac aggccaauau cucgcaaugg      300

acaccgacgg ccuucucuac ggcucccaaa cccccaacga agaaugccuc uuccucgaac      360

gccuagaaga aaaccacuac aacacauaca ucuccaaaaa acacgcagaa aaaaacuggu      420

ucguaggccu caaaaaaaac ggcuccugca aacgcggccc ccgcacccac uacggccaaa      480

aagccauccu cuuccucccc cuacccgucu cauccgacua aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  3469
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt9)

<400>  3469
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguag       60

ggguaggagg aggggaugua gaagauguga cgccaaggcc aggagggugu caaauaagcg      120

gaagaggggc aagaggcugu aacgggauac cgggggcagc ggcgugggag gcagcgcugc      180

cgagaagacg accacgaagg cauccgagug ugaacccgcg gucaagagcg gcagggagcc      240

cgagaacgag agggagaaga acagaggaaa ggccaagugg aaguagauua ggggauaggg      300

gaagagggag ggcgcuaccg ggagggagau ugggagggcg agggagaggg agagcgccag      360

agaggguagg agggcggggg cgggggaggg ggacagcggc gccgagagcg gcaccagcag      420

cgagagggag caggccaggg ccggcgggga cgauggcggc gggaagcaua acaacacugc      480

cggcguuacc ggaggacgga gggagugggg cguucccgcc agggcacuuu aaagauccaa      540

agagguugua uugcaaaaac ggaggguucu uucugaggau acauccagau gggagaguag      600

auggaguaag ggagaaaucg gacccacaca uaaaacugca auugcaagca gaagagagag      660

ggguagugag cauaaaaggg gugugugcaa acagauaccu agcgaugaag gaagauggaa      720

gacuguuagc gucgaaaugu guaacggacg agugcuuuuu cuuugaaagg cucgagagca      780

auaacuauaa cacauacagg agcaggaagu auacaucaug guauguagca cucaagagaa      840

cgggacaaua caagcuaggg agcaagacgg ggccggggca aaaggcaaua cuauuucuac      900

cgaugucggc aaagagcuag ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  3470
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt9)

<400>  3470
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aauggauccu caccuggauc cuacccaccc uccuguaccg cagcugcuuc cacaucaucu      120

gccucgucgg aaccauaucc cucgccugca acgacaugac ccccgaacaa auggccacaa      180

acguaaacug cagcuccccc gaacgccaca cccgcuccua cgacuacaug gaaggcggag      240

acauccgcgu acgccgccua uucugcagaa cccaauggua ccuacgcaua gacaaaagag      300

gcaaagucaa aggcacacaa gaaaugaaaa acaacuacaa caucauggaa auccgcaccg      360

ucgcagucgg aaucguagcc aucaaaggag ucgaaagcga auucuaccua gccaugaaca      420

aagaaggcaa acuauacgcc aaaaaagaau gcaacgaaga cugcaacuuc aaagaacuaa      480

uccucgaaaa ccacuacaac accuacgccu ccgccaaaug gacccacaac ggcggcgaaa      540

uguucguagc ccucaaccaa aaaggaauac ccguccgcgg aaaaaaaacc aaaaaagaac      600

aaaaaaccgc ccacuuccuc cccauggcca ucaccuaagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  3471
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt9)

<400>  3471
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaac       60

uccuccccuc cgucguccuc aaacucuucc uagccgcagu ccucuccgca cucgucaccg      120

gcgaaucccu cgaacgacuc cgacgcggcc uggccgcagg caccuccaac cccgacccac      180

caaccgucuc aacagaccaa cuacuacccc ucggcggagg ccgcgacaga aaaguccgcg      240

accuucaaga agcagaccuc gaccuccucc gagucacccu cuccagcaaa ccccaagccc      300

ucgccacacc caacaaagaa gaacacggaa aacgcaagaa aaaaggcaaa ggccucggca      360

aaaaacgcga ccccugccua cgcaaauaca aagacuucug cauccacggg gaaugcaaau      420

acgucaaaga acuacgcgcc cccucaugca uaugccaccc cggcuaccac ggcgaacgcu      480

gccacggccu cucccucccc guagaaaacc gacucuacac cuacgaccac accaccaucc      540

ucgccgucgu cgccgucguc cucuccuccg uaugccuacu cgucaucgua ggccuccuaa      600

uguuccgcua ccaccgccga ggcggcuacg acgucgaaaa cgaagaaaaa gucaaacucg      660

gaaugaccaa cucccacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  3472
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt9)

<400>  3472
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ucacgaaacu ccucccagca cuacuacuac aacacguccu auuacaccuc cuccuccuac      120

ccauagcaau acccuacgcg gaagggcagc gaaaaagacg caacacgauc cacgaguuca      180

agaaguccgc aaaaacaacc cuaaucaaaa uagaccccgc ccucaaaauc aaaaccaaga      240

aagucaauac cgcagaccaa ugcgcaaacc gcugcacacg caacaaaggc cucccauuua      300

ccugcaaagc cuucguuuuu gacaaagcca gaaagcaaug ccuuugguuc ccauucaaca      360

gcaugagcuc cggcgucaag aaagaguucg gacacgaguu cgaccuguac gaaaacaaag      420

acuacauccg aaacugcaua aucggcaaag gccgcagcua caaaggaaca gucuccauaa      480

ccaaaucagg caucaaaugc cagccuugga gcuccaugau accccacgaa cacucauucc      540

ucccgucaag cuaccgaggg aaagaccuac aagaaaauua cugccgaaac ccacgcgggg      600

aagaaggcgg acccuggugc uucaccucaa acccagaagu ccgcuacgaa guaugcgaca      660

ucccccaaug cucagaaguu gaaugcauga ccugcaaugg agaaagcuac agagggcuca      720

uggaccacac cgaaagcggc aaaauaugcc aacgauggga ccaccaaaca ccacaccgac      780

acaaauuccu ccccgaacga uacccggaca aaggguucga ugacaacuac ugccguaacc      840

ccgacggcca gccacgccca uggugcuaca cacuagaccc acacacucgc ugggaauacu      900

gugcaaucaa aacaugcgcc gacaauacca ugaacgacac agacgucccc cuggaaacaa      960

ccgaaugcau ccaaggccaa ggugaaggcu accgcggcac ggucaauacc auauggaacg     1020

gcauacccug ccaacgaugg gacagccaau acccgcacga acacgacaug acaccagaaa     1080

acuucaaaug caaagaccuu cgggaaaacu acugccgaaa ccccgacgga uccgaaagcc     1140

ccuggugcuu cacaaccgac cccaacaucc gcguaggaua cuguucacaa aucccaaacu     1200

gugacaugag ccacggacag gacugcuaca gagguaacgg caaaaacuac augggcaacc     1260

ucucccaaac acgauccgga cugaccugca gcauguggga caagaacaug gaagaucucc     1320

auagacacau cuucugggaa ccagacgcaa gcaaauuaaa cgaaaacuac ugccgaaacc     1380

ccgacgacga cgcccacggc cccuggugcu acacaggaaa cccucugauu cccugggauu     1440

auugucccau cucccgcugc gagggcgaca ccacccccac aaucgugaac cuagaccacc     1500

ccguaauauc augcgcaaaa acgaaacagc uccgaguugu gaacggcaua ccaacuagaa     1560

cuaacaucgg cuggaugguc ucacuacgau accguaacaa acacaucugc ggagguucgc     1620

uaauaaaaga aagcuggguc cucaccgcac gccaaugcuu ccccagccgg gaucugaaag     1680

acuacgaagc cuggcuggga auacacgacg uccacgguag aggagacgaa aaaugcaaac     1740

agguccucaa cguaucccaa cucguauacg gcccggaggg cagugaccuc guacucauga     1800

aacuagcccg acccgccguc cuugacgacu ucguauccac cauagaccuc cccaacuacg     1860

gcugcaccau cccagaaaag accagcugca gcgucuacgg auggggauac accggccuaa     1920

uaaauuacga cgggcuacuc cgcgucgccc accuguacau caugggcaac gaaaaaugcu     1980

cccagcacca cagaggcaaa guaacccuaa augaaagcga aauaugcgca ggggccgaga     2040

aaaucggcag uggcccaugc gaaggcgacu acgggggccc ccuaguaugc gaacaacaua     2100

aaaugcgcau gguccucgga gugaucgucc ccggacgagg cugcgcgauc ccaaaucgcc     2160

caggcaucuu cguccgcgug gcuuacuacg ccaaauggau acacaaaaua auacuaaccu     2220

acaaaguacc ccaaagcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  3473
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt9)

<400>  3473
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcua       60

aagcggcggc aaucggaaua gaccucggaa ccaccuacuc augcgugggc guuuuucagc      120

acggcaaagu agaaauaaua gcaaacgauc aaggaaacag gacaacuccc ucguacgugg      180

cauuuacaga cacagagaga cugauugggg acgccgccaa aaaccaaguc gcacugaacc      240

cccagaacac aguuuucgac gcgaaaaggc ucauaggacg aaaauucgga gacccagugg      300

uccaaaguga caugaagcac uggccauucc aagugauaaa ugacggcgac aaacccaagg      360

uacaagucuc guacaaaggc gaaaccaagg cauucuaccc agaagagaua ucguccaugg      420

uccucacaaa gaugaaagaa auagccgaag ccuaccucgg guacccaguc acaaacgcgg      480

ucauaaccgu acccgcguac uucaacgaca gccaacgaca agcgacaaaa gacgccggag      540

ucauagcagg ccucaacgua cugcgcauaa ucaacgaacc gaccgcggca gccauagccu      600

acgggcuaga ccgcacagga aaaggggagc gcaacgucuu aaucuucgac cuaggcggag      660

gcacauucga cgucucaaua cuaaccauag acgacggcau cuucgaagua aaagccacag      720

ccggggacac gcaccuaggc ggcgaagacu ucgauaaccg ccuaguaaac cacuucguag      780

aagaguucaa gagaaagcac aagaaagaca uaagccaaaa caaacgggcc gugcgcaggc      840

uaaggaccgc augcgaacgc gcaaaacgaa cccucagcuc aaguacccaa gcaagccugg      900

aaaucgacag ucucuucgaa ggaauagacu ucuacaccuc caucacccga gcgcgauucg      960

aagaacuaug cagcgaccua uuccgcucga cacuggaacc gguggaaaaa gcacucagag     1020

acgcgaagcu agacaaagcc caaauccacg accuaguauu ggugggaggc aguacaagaa     1080

ucccaaaagu acaaaagcuc cuacaagauu ucuucaacgg aagggaccuc aacaaaucca     1140

ucaaccccga cgaagcagug gccuacgggg cagcagucca ggcagccaua cugaugggag     1200

acaaaagcga aaacgugcaa gaccuacucc uccuggacgu agccccacua agccuaggac     1260

ucgaaacagc cggaggagua augacagcac ugauaaaaag gaacagcacc auccccacga     1320

aacaaaccca aaucuucaca acguacucag acaaccaacc cggagugcua auacaaguau     1380

acgaaggcga gcgcgcaaug acuaaagaca acaaccuccu gggcagguuc gagcuaucag     1440

gaauaccacc ggcaccacgg ggagucccgc aaauagaagu gaccuucgac auagacgcca     1500

auggcauacu aaacguaacc gcaaccgaca aaucuaccgg gaaagcaaac aagauaacga     1560

ucacgaacga uaaagggcgc uuaagcaagg aagaaaucga acgcaugguc caagaagcag     1620

aaaaauacaa agccgaggac gaaguacaac gcgaaagagu gagcgcgaaa aacgcacuag     1680

aaucauacgc guucaacaug aaaagcgcag ucgaagacga aggccucaaa gggaaaauau     1740

ccgaggccga uaaaaagaaa guacuagaca aaugccaaga agucauaagc uggcuagacg     1800

ccaacaccuu agccgaaaaa gacgaguucg aacacaaaag gaaagaacug gaacaaguau     1860

gcaaccccau uauauccggc cuauaccaag gagcuggagg accgggaccc ggcggauucg     1920

gagcccaagg ccccaaagga ggaaguggga gcgggcccac gauagaagaa gucgacuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3474
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt9)

<400>  3474
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcga       60

aagccgcagc caucggaaua gaccucggca ccaccuacuc augcgucggc guauuccaac      120

acgggaaagu agagaucauc gcaaacgacc aaggaaacag gaccacacca ucauacguag      180

ccuucacaga caccgagcgc cuaaucggag acgccgccaa gaaccaaguu gcgcucaacc      240

cacaaaacac agucuucgac gcaaaacgac ugauaggccg aaaauucggc gacccagugg      300

uccaauccga caugaagcac uggccauucc aaguaaucaa ugacggagac aaacccaaag      360

uacaggucag cuacaaagga gaaacaaagg ccuucuaccc agaagaaaua agcucaaugg      420

uccugaccaa aaugaaagaa auagcagagg cuuaccucgg cuaccccgua acaaacgcgg      480

ucaucaccgu acccgcauac uucaacgaca gccaacggca agccacgaaa gacgccggag      540

ucauagcagg ccuaaacgua cuccgcauua uaaacgaacc aaccgccgcc gccaucgcau      600

acggacucga ccgaacaggc aagggcgaga gaaacguacu gaucuucgac cucggaggag      660

gaacauucga cgucaguaua cucacgaucg acgacggaau auucgaggua aaggcaacgg      720

cuggagacac acaccuaggc ggagaagacu ucgacaacag gcuugucaac cacuucgucg      780

aagaguucaa acgaaaacac aagaaagaca uaagccaaaa caaaagggcc guccguagac      840

uaagaaccgc cugcgaaaga gcgaaaagga cacucagcuc cucaacccaa gcaagccuag      900

aaauagacuc acuauucgaa ggcaucgacu ucuacaccuc gaucacccgu gcacguuucg      960

aagaacuaug cagcgaccuc uuccgcucaa cccuagaacc cguagaaaaa gcacuacgag     1020

acgcgaaacu agacaaagcg caaauacacg accugguccu aguaggaggc ucaacaagaa     1080

uaccuaaagu acaaaaacuc uugcaagauu ucuucaaugg ccgcgaccuc aacaaaagca     1140

uaaacccaga cgaagccguc gcauauggag ccgcggugca ggcagcaauc cuaaugggag     1200

acaaaagcga aaacgugcaa gaccugcugc uccuagacgu agcaccacuc ucacuuggcc     1260

ucgaaaccgc aggaggcgua augacugcac uuaucaaaag gaacucgacc auacccacca     1320

aacagacaca aaucuucacu acauacucgg acaaccagcc cggaguccuu auccaaguau     1380

acgagggcga acgcgcgaug acaaaagaca acaaccuacu cggaagauuc gaacucucag     1440

gaauaccacc agccccacgc ggcgucccac aaaucgaagu aacauucgac aucgacgcga     1500

acggaauauu aaacgucaca gccacagaca aaucgaccgg aaaagcaaac aaaauaacaa     1560

ucacaaacga caaaggccga cuuaguaaag aagaaaucga gcgaauggug caagaagcgg     1620

agaaauacaa agcagaagac gaaguacaaa gagagcgagu auccgccaag aacgcccucg     1680

aaucauacgc cuucaacaug aaaagcgcgg ucgaagacga aggccuaaag gggaagauaa     1740

gcgaagcaga caagaagaaa guacuagaca aaugccaaga gguaaucagc uggcuagacg     1800

caaacacccu cgcugaaaaa gacgaguucg aacacaaacg aaaagaacuc gagcaagucu     1860

gcaaccccau aaucucgggc cucuaucagg gagcgggagg acccggccca gggggcuucg     1920

gagcgcaagg acccaaaggc ggcagcggaa gcggccccac aaucgaagaa guagacuagg     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3475
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt9)

<400>  3475
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

cagccaaggg gaucgcaauc ggcaucgacc uaggaaccac auauuccugc guaggagucu      120

uccagcacgg caaaguggaa auaaucgcaa acgaucaagg caacagaaca accccaagcu      180

acguagcauu caccgacaca gagagacuga ucggcgacgc cgcgaaaaac caaguggcaa      240

ugaacccaca gaacaccguc uucgacgcca aacggcucau aggcagaaaa uucaacgacc      300

ccguaguaca agccgacaug aaacucuggc ccuuucaagu cauaaacgaa ggcggaaagc      360

ccaaaguccu aguaagcuac aaaggcgaaa acaaggccuu cuaccccgaa gaaaucucga      420

gcaugguccu caccaagcug aaggaaacag cagaagccuu ccuaggccac ccaguaacaa      480

acgccguaau aacagugcca gcauacuuca acgacagcca acgacaagcg accaaggaug      540

cggguguaau agcgggccuc aacguccuac gaaucauaaa cgaaccuaca gcggccgcca      600

ucgccuacgg acuggacaaa ggaggccagg gagaaagaca cguacugaua uucgaccuag      660

gaggcggcac cuucgacguc ucaauacuga ccaucgacga uggcaucuuc gaaguaaaag      720

ccacugcagg cgacacccac cucggcggcg aagacuucga caaccggcuc gucagccauu      780

ucgucgaaga auuuaaaagg aaacacaaga aagacaucuc ccagaacaaa agagcaguca      840

gacgacuucg gaccgcgugc gaacgcgcaa aacgcacgcu aagcagcagu acacaagcaa      900

accuagaaau cgacucccuu uacgaaggaa ucgacuucua cacaucaauc acccgcgcaa      960

gguucgagga gcucugcgcc gaccucuucc guggcacccu agaacccguc gaaaaagcac     1020

uccgcgacgc caaaauggac aaggcaaaaa uacacgacau cguacucguc gggggcucaa     1080

ccagaauccc caagguccag cgccuacuac aagauuacuu caacggacga gaccucaaca     1140

aaagcauaaa uccagacgaa gcggucgcgu acggcgcagc aguacaggcc gcgauccuaa     1200

ugggggacaa aagcgaaaaa guccaagacc uccuccugcu agacguagca ccgcuuuccc     1260

uaggccuaga aacagccgga gguguaauga ccgcccuaau caaacgcaac agcacaauac     1320

ccaccaaaca aacccaaauc uucaccacau acagcgacaa ccagccgggc guccucauac     1380

agguuuacga aggcgaacgc gcaaugacaa aagacaacaa cuuacuagga cgauucgacc     1440

ugaccggcau cccaccagca cccagaggcg ucccccaaau agaaguaacc uuugacauag     1500

acgccaacgg cauacuaaac guaacagcca cagacaaaag uacgggcaaa gucaacaaaa     1560

ucaccauaac caacgacaaa ggcaggcucu caaaagaaga aaucgaacgg augguccuag     1620

acgcagaaaa auacaaagca gaagacgaag uacagcgaga gaaaauagcg gccaaaaacg     1680

cacucgaaag cuacgccuuc aacaugaaaa gcguuguauc cgacgaagga uuaaaaggaa     1740

aaauaagcga aagcgacaaa aacaaaauac ucgacaaaug caacgaacuc cuguccuggc     1800

uggaaguaaa ccaacucgcc gaaaaagacg aguucgacca caaacgaaaa gaacucgaac     1860

aaaugugcaa ccccauaauc accaaacugu accaaggcgg uugcaccgga ccagccugcg     1920

gaaccggcua uguacccgga cgcccagcga caggcccaac caucgaagag gucgacuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3476
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt9)

<400>  3476
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

cacgcggccc cgcaaucggg aucgaucuag gcaccacaua cucgugcgua ggcguauucc      120

aacacgggaa agucgaaauc aucgcaaacg accaaggaaa ccgcaccacc cccagcuacg      180

uagccuucac cgacaccgaa cgacucaucg gagacgcagc caaaaaccag guagcaauga      240

acccaaccaa cacaaucuuc gacgcaaaaa ggcugauagg ccgaaaauuu gaggacgcca      300

cgguccaaag ugacaugaaa cauuggcccu uccgcguagu auccgaagga ggcaaaccca      360

aaguccaagu agaauacaag ggcgagacca agaccuucuu cccggaagaa auauccagca      420

ugguccugac caaaaugaaa gaaauagccg aagccuaccu ugggggaaaa guccacagcg      480

ccgucauaac cguuccagcc uacuucaacg acagccaacg gcaagccacg aaagacgcag      540

gcacaauaac aggacucaac guccuucgaa uaauaaacga accaaccgca gccgcgaucg      600

cauacgggcu cgacaaaaag gggugugcag ggggcgagaa aaacguguua auauuugacc      660

uaggcggggg caccuucgac guaagcaucc ucaccauaga agacggcaua uuugaaguca      720

aaagcaccgc cggagacaca caccugggag gagaagacuu cgacaaucgg augguaagcc      780

accucgcaga agaguucaag cgcaagcaca agaaagacau ugggccaaac aaaagggccg      840

ugcgacgccu cagaaccgca ugcgaacgcg caaaacgcac ccugagcuca aguacgcaag      900

caagcaucga aauugacagu cuguacgaag gaguagacuu cuacacauca auaacacgag      960

cacgcuucga agaacucaac gccgaccucu uccgcggaac acuagaaccc gucgaaaaag     1020

cacuccggga cgcaaaacug gacaaaggcc aaauccaaga aauaguacuc gucgggggau     1080

ccacccgaau accaaagaua cagaaacuac ugcaagacuu cuucaacggg aaagaacuaa     1140

acaagucgau aaaccccgac gaagcaguag cguacggcgc cgccguacaa gccgcgaucc     1200

ugauaggaga uaaaagugaa aacgugcaag accuacugcu ccuggacguc acgccccuau     1260

cacucgggau cgaaaccgcu ggcggaguaa ugacaccccu cauaaaaagg aacaccacca     1320

uaccaaccaa acaaacccaa acauucacca ccuacucgga caaccaauca ucugugcuag     1380

uacaaguaua cgaaggcgaa cgggcuauga cgaaagacaa caaucuacua gguaaguucg     1440

accuaacagg cauacccccg gcaccccgag gaguaccaca aauagaagua accuucgaca     1500

ucgaugcaaa cgggauacua aacguaaccg cagccgacaa aucgaccgga aaagaaaaca     1560

aaaucacaau cacaaacgac aaaggacgcc ucagcaaaga cgacauagac cgaaugguuc     1620

aggaagcaga gagguacaag agcgaagacg aagcgaaccg agaccgagug gcggccaaaa     1680

acgcacugga aagcuacacc uacaauauaa aacaaacagu ugaagacgaa aaacuccgug     1740

gaaagaucag cgaacaagac aaaaacaaaa uacuagacaa augccaagaa gucauaaacu     1800

ggcuggaccg aaaccagaug gccgaaaaag augaauacga acacaaacaa aaagagcuag     1860

agcgcguaug caaccccaua aucucgaaac uguaccaagg cggaccagga ggaggaagcg     1920

gaggaggagg aucgggcgca agcggcggcc cgacaaucga agaggucgac ugaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  3477
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt9)

<400>  3477
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uaguaggcau cgaccuaggg uuucagagcu gcuacgucgc agucgcaaga gcggguggca      120

uagaaacaau agcaaacgaa uacagcgaca gaugcacccc cgcaugcauc ucguuuggcc      180

ccaaaaauag aagcauugga gcugcagcca aaagccaagu caucagcaac gcgaaaaaca      240

cgguacaagg cuucaagcgg uuucacggaa gggcauucag cgaccccuuc guugaagcgg      300

agaaguccaa ccuagcguac gacaucgucc aacuacccac cggacugacc gguauaaaag      360

uaacauacau ggaagaagaa aggaacuuua caacagaaca aguaaccgcc augcuccuca      420

gcaaacuaaa agaaacagca gaauccgucc ucaagaaacc cgucgucgac ugcgucgugu      480

cgguccccug cuucuacacc gaugcagaaa ggcgcucagu cauggacgcg acgcagauag      540

cggggcucaa cugccuacgc cuaaugaacg agacgacagc agucgcccuc gccuacggca      600

ucuacaaaca agaccuuccc gcacuagaag aaaaaccccg aaaugucguc uucgucgaca      660

ugggacacuc agcauaccaa guaucuguau gcgcguucaa ccgaggcaaa cuuaaagugc      720

uggccaccgc cuucgacaca acacucggcg gccggaaauu cgacgaaguc cuaguaaauc      780

acuucugcga agaguucggc aagaaauaua aacuagauau aaaauccaaa auacgcgccc      840

uccugcgcuu gagccaggaa ugcgaaaaac ucaaaaagcu aaugagcgca aacgcgucag      900

accugccacu gagcauagaa ugcuucauga acgacguaga cguauccgga accaugaacc      960

ggggaaaauu cuuagaaaug ugcaacgacc uccuagcacg cguugaaccc ccucuaagau     1020

cugugcugga acaaacaaaa cugaagaaag aagacaucua cgcaguagaa aucgucggag     1080

gggcaacucg aauaccggcc gucaaagaga aaaucagcaa auucuucggg aaggaacuca     1140

gcaccacccu gaacgcagac gaagcgguaa ccaggggcug cgcgcuccaa ugcgccauac     1200

ugucaccagc cuucaaagua cgagaguuca gcauaacaga cgugguccca uacccaauaa     1260

gccuccgaug gaacucacca gcagaagaag gcucgagcga cugcgaagua uucagcaaaa     1320

accacgcagc accauucucc aaaguccuca cguuuuaccg gaaagaaccg uucacccucg     1380

aggcauacua cuccucaccc caagaccucc ccuaccccga cccagccauc gcacaauuca     1440

gcguccaaaa ggucacuccc cagagcgacg gcaguagcag caaagucaaa gucaaagucc     1500

gcgucaacgu acacgggauc uucagcguau caucagccag ccucguggaa guccacaaga     1560

gcgaggaaaa cgaggaacca auggagaccg accaaaacgc caaagaagaa gagaaaaugc     1620

aagucgacca ggaagaaccc cacguagaag aacagcagca gcaaaccccc gcggaaaaca     1680

aagcagaauc cgaagaaaug gaaaccucgc aagccggcag uaaagacaag aaaauggacc     1740

aaccacccca agcaaagaaa gcaaaaguaa aaacguccac aguagaccug ccaauagaga     1800

accaacuacu uuggcaaaua gaccgagaaa ugcuaaacuu auacaucgag aacgaaggga     1860

aaaugaucau gcaagauaaa cuagaaaaag aaagaaacga ugccaaaaac gcagucgaag     1920

aguacguuua cgagaugcgg gacaaacuaa gcggcgagua cgagaaguuc gucuccgagg     1980

acgaccgcaa cagcuucaca cugaaacucg aagacaccga aaacuggcua uacgaagacg     2040

gcgaagacca accaaagcaa guauacgucg acaagcucgc ggaacucaaa aaccucggcc     2100

aaccaauaaa aauccgguuc caagaaagcg aggagagacc aaagcuauuc gaagaacucg     2160

gaaaacaaau ccagcaauac augaaaauua uaucaaguuu caaaaacaaa gaagaucaau     2220

acgaucaucu ggacgccgca gacaugacaa aaguagaaaa aucgaccaac gaagcaaugg     2280

aauggaugaa caacaaauua aaucugcaaa acaaacaaag ccuaaccaug gaccccguag     2340

uaaaaucaaa agagaucgaa gccaaaauca aagaacucac cuccacaugc agccccauca     2400

uaagcaaacc caagcccaaa gucgaaccac ccaaagagga acagaaaaac gcagaacaaa     2460

acggccccgu cgauggacag ggcgauaacc ccggaccgca agccgccgaa caaggcacgg     2520

acacagccgu gcccucagac agcgacaaga aacuaccaga aauggacauc gacuaaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  3478
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt9)

<400>  3478
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucag       60

ucgucggaau agaccucgga uuccucaacu gcuacauagc cguagcacgc uccggaggua      120

uagagacaau cgccaaugag uacuccgaca gguguacccc cgcgugcauc agccugggcu      180

cccgcacucg cgccaucggc aacgcggcga agucccaaau cgucaccaac gucagaaaca      240

caauccacgg auucaagaaa cuccacggac gauccuucga cgaccccaua guccaaaccg      300

agcgcauacg ccugcccuac gaacuacaga aaaugccaaa uggcagcgcc ggcguaaaag      360

uccgcuaccu cgaggaggaa cgccccuucg ccaucgaaca agucacaggc augcuauuag      420

caaagcucaa agagaccucc gaaaaugcac ucaagaaacc cguggcagac ugcguaauca      480

gcauuccguc cuucuucaca gacgcagagc gacggucagu cauggcagcc gcacaagucg      540

ccggccugaa cugucuccga cugaugaaug agacaacggc cgucgcccuc gcauacggca      600

ucuacaaaca agacuuaccu ccgcucgacg aaaaaccgag aaacgucguc uucaucgaca      660

ugggacacag cgcauaccaa guccucguau gugcauucaa caaaggaaaa cuaaaaguuc      720

uugccaccac auucgaucca uaccucggag gccgcaacuu cgacgaagca cucguugacu      780

acuucuguga cgaguucaaa acaaaauaca aaauaaacgu caaagaaaac agccgcgccc      840

uucuccgucu auaccaggag ugcgaaaaac ucaagaaacu caugagcgcc aacgccagcg      900

aucucccacu aaacaucgaa uguuucauga acgaccugga cgugaguucc aaaaugaacc      960

gugcccaauu cgagcaacuc ugcgccagcu uacuagcaag aguagaacca ccacucaaag     1020

cggucaugga gcaagccaau cuccaacggg aagacaucag cuccauagag aucgucgggg     1080

gagcaacccg aauacccgcu guaaaagaac aaauaacuaa auucuuccua aaagacauaa     1140

gcacaacccu gaacgccgac gaagcagucg cccgaggcug cgcacuccag ugcgccauac     1200

ucucccccgc guucaaagua cgcgaguuca guaucacaga ccucguacca uacucaauca     1260

cccuacgcug gaagacaucu uucgaagacg gcuccggaga augcgaaguc uucugcaaaa     1320

aucaccccgc ccccuuuucc aaagucauca cauuccacaa aaaggaaccg uucgaacucg     1380

aagcguuuua cacgaaccuc cacgagguac cauaccccga cgcgagaaua ggaucauuca     1440

ccauacaaaa cguauuccca caauccgacg gcgauucauc caaggucaaa gucaaaguaa     1500

gagucaacau acacggcauc uuuucagucg ccagcgccag cgugauugag aaacaaaacc     1560

uugaaggcga ucacagcgac gcccccaugg aaaccgaaac gagcuucaag aacgaaaaca     1620

aggacaacau ggacaagaug cagguagacc aagaggaagg acaccaaaaa ugccaugcag     1680

aacacacacc cgaggaagaa aucgaccaca ccggagccaa aacgaagucu gccgucagcg     1740

auaagcagga ccgucucaac caaacccuca agaaaggcaa aguaaaaagc auagaccuac     1800

caauccaaag cucacucugc cgccaacucg ggcaagaccu ccuaaacucc uacauagaaa     1860

acgaaggcaa aaugaucaug caagauaaac uagaaaaaga acgcaacgac gccaaaaacg     1920

cagucgaaga auacgucuau gacuuccgag accggcucgg aaccgucuac gaaaaauuca     1980

uaacccccga ggaccuauca aaacuaagcg cuguccuaga agacaccgag aacuggcuau     2040

acgaagacgg agaggaccaa ccaaaacaag uauacguaga caagcuccag gagcucaaga     2100

aauacggcca acccauccag augaaauaca uggagcauga agaaagaccc aaagcacuca     2160

acgaccucgg caagaaaauc cagcucguua ugaaaguaau agaagccuac cgaaacaaag     2220

acgagcgcua cgaccaccua gacccaaccg aaauggaaaa agucgaaaaa ugcaucagcg     2280

augccaugag cuggcucaac uccaagauga acgcgcagaa caaacuaucc cucacccaag     2340

accccguagu aaaaguauca gaaauagucg caaaaucgaa agaacuggac aacuucugca     2400

acccaaucau cuacaagccg aaaccuaaag cagaggugcc agaagacaaa ccaaaagcaa     2460

auagcgaaca caacggacca auggacgggc aauccggaac agaaaccaaa agcgauagca     2520

caaaagacuc aucccagcac acaaaaagcu caggggaaau ggaggucgac uagggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  3479
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt9)

<400>  3479
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaac       60

uaagccuagu agcggcaaug cuccugcucu uaagcgccgc aagagcagaa gaagaggaca      120

agaaagagga cgucggcacc gucgucggca uagaccuagg caccacguac agcugcgucg      180

ggguauucaa aaacggaaga gucgaaauca ucgccaacga ccaaggcaac agaaucacac      240

ccagcuacgu agccuucacc cccgaaggag aacgccucau aggagacgcg gccaaaaacc      300

aacucaccag caacccagag aacacaguau ucgacgcaaa acggcuaauc ggccggaccu      360

ggaacgaccc cagcguccaa caagacauaa aauuccuccc cuucaagguc gucgagaaga      420

aaacaaaacc auacauucaa gucgacauag gaggagguca aacgaaaaca uucgcacccg      480

aggagauaag cgcaauggua cucaccaaaa ugaaagaaac cgcagaagca uaccuuggaa      540

agaaagucac gcaugccguc gucacagucc cagccuacuu caacgacgca caaagacagg      600

cgaccaaaga cgccggcaca aucgcaggac ugaacguaau gcgcauaauc aacgagccca      660

ccgccgcagc caucgcuuac gggcuagaca aacgagaagg agagaaaaac auccucgugu      720

ucgaccuagg aggaggcaca uucgacguca gccuccuaac aaucgacaac ggaguguucg      780

aagucguagc caccaacggc gacacgcacc ucggaggaga ggauuucgac caaagaguaa      840

uggaacacuu uaucaaacua uacaaaaaga aaacaggcaa agacguacga aaagacaaca      900

gagccgugca aaaacuucga cgugagguag aaaaagccaa acgagcacug ucgagccaac      960

accaagcaag aauagaaauc gagagcuucu acgaaggcga agacuucagc gaaacccuca     1020

cucgagcaaa auuugaagaa cuaaacaugg accucuucag aagcacaaug aagccaguac     1080

agaaggugcu cgaagacuca gaccucaaga aaagcgauau agacgaaauc guccucgucg     1140

ggggcagcac ccggauaccg aaaauccaac aacucgucaa agaguucuuc aacggaaaag     1200

aaccuagccg uggaaucaac ccagacgaag ccgucgcgua cggagccgcg guccaggcag     1260

gcguccuauc aggcgaucaa gacacaggcg accucguccu acuagacgug ugcccacuaa     1320

cacucggaau cgaaaccgug ggcggaguca ugaccaaacu aauaccccgc aacacagucg     1380

uucccacgaa gaaaagccaa auauucagca cggccucaga caaccagccc accguaacaa     1440

ucaaagucua cgaaggggaa cgcccacuca ccaaagacaa ccaccuccug ggcacguucg     1500

aucugacagg cauaccaccc gcgccccgcg gagucccgca aaucgaagua acauucgaaa     1560

uagacgugaa cgggauacug cgcgucacag ccgaagacaa aggaaccgga aacaaaaaca     1620

aaaucacaau aacaaacgac caaaaccgcc uaacaccaga agaaauagaa agaaugguaa     1680

acgacgccga aaaauucgca gaagaggaca agaaacuaaa agaacgcaua gacacccgaa     1740

acgaacucga aucauaugca uacucccuca aaaaccagau cggcgacaaa gaaaaacuag     1800

ggggcaaacu gagcuccgag gacaaggaaa caauggaaaa agcaguagag gagaaaaucg     1860

aauggcugga aagccaucaa gacgcagaca uagaggacuu caaagccaag aagaaagaac     1920

uugaagagau cguacaacca auaaucucaa aacucuacgg cucggcagga ccaccaccga     1980

caggagaaga agacacggcc gaaaaagacg aacuguaggg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  3480
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt9)

<400>  3480
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

ccccaagaga acuagccgug gggaucgacc ucgggacaac auacuccugc guaggcgugu      120

uccaacaagg aagagucgaa auauuagcaa acgaccaagg caacaggacc acaccaucgu      180

acguagcguu cacagacaca gaacgccuag ugggagacgc agcaaagucg caagcagcac      240

uaaauccaca caacacgguc uucgacgcaa agaggcuaau aggaaggaag uucgccgaca      300

caaccguuca aagcgauaug aagcacuggc cauucagagu cgucucggaa ggagggaaac      360

caaaagugcg ggucugcuac agaggcgaag acaaaacauu cuacccagaa gagaucucca      420

gcaugguacu gagcaaaaug aaggaaacag ccgaagccua ccucggccaa ccagucaagc      480

acgcggucau aaccguaccc gccuacuuca augacagcca gcgccaagcc acaaaagacg      540

ccggggcaau agccggacua aacguacuac gaaucaucaa cgaacccacg gcagcagcga      600

uugcauacgg ccuagaccga aggggcgccg gagaacgcaa uguccugaua uucgaccugg      660

gagggggcac auuugacguc uccguacuau caauagacgc aggaguauuc gaagugaaag      720

cgacggcagg agacacgcac cuaggcggcg aagacuucga caaccgucua gugaaccacu      780

ucauggaaga guucaggcga aaacacggaa aagaucucag cggaaacaaa cgcgcacucc      840

gcaggcuaag aaccgcaugc gaacgcgcaa aaaggacccu aagcuccucg acacaggcca      900

cccucgaaau agacucccua uucgaaggag ucgacuucua cacaagcauc acccgcgcgc      960

gauucgaaga acuaugcagc gaccuuuucc gcucaacccu agaaccaguc gaaaaagcuc     1020

uccgcgacgc aaaauuagac aaagcacaaa uccacgaugu cguccuagua ggcggcucaa     1080

cgcgcauacc aaaaguacaa aagcuccugc aagacuucuu caacgggaaa gaacuaaaca     1140

aauccauaaa ccccgacgaa gcggucgccu acggcgcggc gguacaagca gcgguccuga     1200

ugggcgacaa gugcgaaaaa gugcaagacc uacuacuccu cgacgucgcc ccauuaagcc     1260

ucggacugga gacggcagga ggaguaauga caacacuaau ccagcgaaac gcgaccauac     1320

ccacaaagca aacccaaacc uuuaccacgu acucagacaa ccaaccggga gucuucaucc     1380

aaguauauga gggcgaacgc gcaaugacaa aagacaacaa ccucuugggc cgcuucgaac     1440

ucuccggcau cccacccgcg ccccgaggcg uaccgcaaau agaagugacc uucgacauag     1500

acgccaacgg gauacuaagc guaaccgcga cagaccgguc aaccggcaaa gcgaacaaaa     1560

ucacaaucac caacgacaaa ggacggcuaa gcaaagaaga aguagaacgc augguccacg     1620

aagccgaaca auacaaagcc gaagacgaag cccaacguga ccgcgucgca gcgaaaaacu     1680

cacucgaagc ccacguguuc cacguuaaag gaucccucca agaagaaagc cugcgcgaca     1740

agauacccga agaagaccgg agaaaaaugc aggacaaaug ccgugaagua cucgccuggc     1800

ucgaacacaa ccaacuagcc gaaaaagaag aauacgagca ucaaaaacga gaacuggaac     1860

aaauuugcag acccauauuu ucgagacugu acgggggccc aggcguccca ggaggcucaa     1920

gcugcggaac ccaagccaga caaggagacc ccagcacagg accaaucaua gaggaaguag     1980

acuagggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  3481
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt9)

<400>  3481
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

caccccgcga acucgcagua ggcaucgacc uaggcaccac cuacuccugc guaggcgucu      120

uccaacaagg ccgcguagaa auacucgcca acgaccaagg caaccgcacc acccccuccu      180

acgucgcauu caccgacacc gaacgccucg uaggcgacgc cgcuaaaucc caagccgccc      240

uaaaccccca uaacaccguc uucgacgcca aacgacucau cggccgaaaa uucgcagaca      300

ccaccguaca auccgacaug aaacacuggc cuuuccaagu cguaucagaa ggaggaaaac      360

caaaaguccg cgucugcuac cgcggagaag acaaaacuuu cuaccccgaa gaaauaucca      420

gcaugguccu aucaaaaaug aaagaaaccg ccgaagcaua ccucggccaa cccgucaaac      480

acgccgucau caccguccca accuacuucu ccaacuccca aagacaagcc accaaagaug      540

caggcgccau agccggccua aaaguacucc ccaucaucaa cgaggccacc gccgcagcca      600

ucgccuaugg acuagaucgc cgcggcgccg gcaaacgaaa cguccugaua uucgaccucg      660

gcggcggcac cuucgacguc ucaguacuca gcauagacgc aggcgucuuc gaaguaaaag      720

caaccgcagg agauacacau cucggcggcg aagacuucga caaucgacuu gucaaccacu      780

ucauggaaga guucagacgc aaacacggca aagaccuauc aggcaacaaa cgcgcccuac      840

gccgccuacg aaccgccugc gaaagagcca aacgaacacc cagcuccucu acgcaagcaa      900

cacucgaaau agacucccuc uucgaaggcg ucgacuucua caaauccauc acccgagcac      960

gauucgaaga auuaugcucc gaccuguucc gcagcacccu cgaacccgua gaaaaagccc     1020

ucagagacgc aaagcuggac aaagcccaaa uccacgacuu cguccucgga ggcggccucc     1080

acucccaccc ccaaggcgca gaaguagcug caggccuccu acaacgacag ggagccgaac     1140

aagaacacca acccuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  3482
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt9)

<400>  3482
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucaa       60

aaggaccggc cgucggaauc gaccucggca ccaccuacag cugcgucggc guguuccaac      120

acggaaaagu ggaaaucauc gcaaacgauc aaggcaacag gaccacaccc ucguacgugg      180

cauuuaccga caccgaacgc cucauuggag acgcggccaa aaaccaggua gcaaugaacc      240

ccaccaacac cgucuucgac gcaaaaaggc uaaucggcag acgauucgac gacgcagucg      300

uccagagcga caugaaacac uggccauuca ugguggucaa ugacgcaggc cgaccaaaag      360

uccaagucga auacaaaggc gaaaccaaga gcuucuaccc cgaagaagua uccagcaugg      420

ugcugaccaa aaugaaagaa auagcagagg cauaccuagg aaagaccguc acgaacgcag      480

ucgugacagu acccgcauac uucaacgacu cacaacgcca agccacaaaa gacgccggaa      540

caauagccgg ccuaaacgua cuacgcauaa uaaacgaacc aacagcagca gcaaucgccu      600

acggacucga caaaaagguc ggggccgaac gcaacguccu aaucuucgau cuaggaggag      660

ggacauucga ugucagcauc cugacaauag aagacgggau auucgaaguc aaaagcacag      720

ccggcgacac ccaccucgga ggagaagauu ucgacaaccg cauggucaac cacuuuauag      780

ccgaguucaa gcgcaagcac aagaaggaca ucagcgaaaa caaacgagcc guacgccgac      840

uacgcaccgc cugcgaacga gcaaaacgca cccugucaag cagcacgcaa gcgagcauag      900

agaucgacag ccucuacgaa ggcauagacu ucuacacauc cauaacgcga gcacgguucg      960

aagaacucaa cgccgaccug uuccgcggca cccuagaccc aguagaaaaa gcccuacgag     1020

acgccaaacu cgacaaauca caaauccacg acauaguucu ggucggcggc uccacaagaa     1080

ucccuaaaau ccaaaaacua cuccaagacu ucuucaacgg aaaagaacuc aacaaaagca     1140

uaaaccccga cgaagcagug gcguacggag cagccgucca agccgcgauc cuauccggcg     1200

acaagagcga aaacguucaa gaccuucucc ucuuggacgu aaccccgcua ucauuaggaa     1260

uagaaaccgc gggaggagua augacaguac uaaucaaaag gaacacuaca auaccgacca     1320

aacaaacaca aaccuucacg acauacucag acaaccaacc aggcgugcuc auacaagucu     1380

augaaggaga acgcgcaaug acaaaagaca acaaccuacu cggcaaguuc gaacucacag     1440

ggaucccacc cgcaccccgc ggaguaccac aaauagaagu aaccuucgac aucgacgcca     1500

acggaauccu caacgucagc gccgucgaca aaucaacagg aaaagagaac aaaaucacga     1560

uaacaaacga caaagggcgc cugagcaaag aagauaucga acgaaugguu caggaagccg     1620

agaaauacaa agcagaggac gaaaagcaac gcgacaaagu cagcuccaaa aacucccuag     1680

aaucauacgc guucaacaug aaagcgacgg ucgaagacga aaaacuacaa ggcaaaauua     1740

acgaugagga uaaacagaaa auacuagaca agugcaacga aaucauaaac uggcucgaca     1800

agaaccaaac agcagaaaaa gaagaguucg aacaucaaca aaaagaacuc gaaaaagucu     1860

gcaaucccau aauaaccaaa cuguaccaaa gcgcgggcgg gaugcccggc gguaugccgg     1920

gaggcuuccc cggaggcggc gccccaccaa gcggcggcgc auccucaggc ccaaccaucg     1980

aagaagucga cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  3483
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt9)

<400>  3483
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauaa       60

gcgccagccg cgcagccgcg gcgaggcuag uaggcgcagc ggcaaguaga ggaccgacgg      120

cggcaagaca ccaagacuca uggaacggcc ugagccacga ggcguucaga cuggugagcc      180

gacgcgacua cgcaagcgag gccaucaaag gagcagucgu cggaaucgac cuagggacga      240

cgaacucgug cguagcagug auggagggaa agcaggcgaa gguccuggag aacgcggaag      300

gagcgagaac cacgccauca gucguagcau ucaccgcgga cggagagagg cucgugggaa      360

ugccagcgaa aaggcaggca guaacaaacc caaacaacac cuucuacgcg acaaaaaggc      420

uaauagguag aagauacgac gauccagaag ugcaaaagga caucaaaaac guacccuuca      480

agauaguacg agccagcaac ggagacgcau ggguagaggc acauggcaag cuauauagcc      540

cgagccagau aggggcguuc guccucauga agaugaagga aacggcagag aacuaccugg      600

gacacacggc aaagaacgcg gucauaacag ugccagcgua cuucaacgac agccaacggc      660

aagcgacaaa ggacgcaggg cagauaagug gacucaacgu ccuacgcguc auaaacgaac      720

caacagcggc ugcccucgca uacgggcucg acaagagcga agacaaagua auagcaguau      780

acgaccuggg cggaggcaca uucgacauau cuauacuaga aauccagaaa gggguauucg      840

aaguaaaguc cacaaacggc gacacguucc uuggagggga agacuucgac caagcgcuau      900

ugcgucacau cguaaaggag uucaagagag agacaggagu agaccucaca aaagacaaca      960

uggcgcugca acgaguaaga gaagcagcag aaaaagcgaa gugugaacua agcucuagcg     1020

uacaaacaga cauuaaccuc ccauaucuca caauggacag uucagggccg aaacaccuaa     1080

acaugaagcu cacaagagcc caguucgagg gaauagugac cgaccuaauc cgcaggacaa     1140

uagcgccgug ccaaaaggcg augcaggacg cagaagugag caagagcgac aucggagaag     1200

ucauauuagu agggggaaug accaggaugc cgaaagugca acagacggug caggaccugu     1260

ucggcagagc accgagcaag gcaguaaacc cagacgaggc aguagcgauc ggagcggcca     1320

uacaaggggg aguacuugcg ggagacguaa cggacguacu acuauuggac gugacgccau     1380

uaagccuagg aauagaaaca cuagguggcg uguucacuaa acucaucaau cgaaacacca     1440

cgauacccac aaagaaauca caaguguuca gcacagcggc cgacggacag acccaggucg     1500

agauaaaagu augccaagga gagcgagaaa uggccgggga caacaaacua cucgggcaau     1560

ucacacugau aggaauaccg ccagcaccca ggggaguacc ccagauagag guaacauucg     1620

acaucgacgc gaacggaaua guccacguca gcgcaaaaga caaaggaacu ggcagggagc     1680

aacaaauagu gauccaaagc agcggcggac ugagcaagga cgacauagag aacaugguga     1740

aaaacgcgga aaaauacgcg gaggaggaca ggagaaagaa agaaagggua gaagcaguaa     1800

auauggcgga agggauaaua cacgauaccg agaccaagau ggaagaguuc aaggaucaac     1860

ucccagcgga cgaaugcaac aaauuaaaag aagaaauaag caagaugagg gaacuacuag     1920

cgcgcaaaga uagcgaaacg ggagaaaaca uaagacaagc cgcgagcagu cuccagcagg     1980

ccagccuaaa acuauucgaa auggcguaca agaaaauggc aagcgaaaga gaagggagcg     2040

ggagcagcgg aacaggagag caaaaagaag aucagaaaga agagaagcag uaaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  3484
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt9)

<400>  3484
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

acaaagaggc aggcggaagc gacggacccc gagaaacagc cccaacaucc gccuacucca      120

gcccagcaag aucacucggc gacaccggca ucacaccacu cucaccgucu cacaucguca      180

acgacaccga uucaaacgua uccgagcaac aauccuuccu aguagucguc gccgucgacu      240

ucgggacaac cuccuccggc uacgcauauu ccuucacaaa agaacccgaa ugcauccacg      300

ucaugcgccg cugggaagga ggagaccccg gcguauccaa ccagaaaacg cccacuacca      360

uccuacuaac ccccgaacga aaauuccacu ccuucggcua cgcugcccga gacuucuacc      420

acgaccucga cccaaacgaa gccaaacaau ggcucuaccu agaaaaguuc aaaaugaaac      480

uucauaccac aggcgaccuc accauggaca ccgaucuaac cgccgcaaac ggcaagaaag      540

ugaaagcucu ugaaaucuuc gccuacgccc uucaauacuu caaagaacaa gcacuaaaag      600

aacucuccga ccaagcaggc ucagaguucg aaaacuccga cguucgcugg gucaucacag      660

uccccgcaau auggaaacaa cccgccaagc aauucaugcg acaagcagca uaccaagccg      720

gucucgcaag cccagaaaau ucagaacaau uaaucauagc acucgaaccc gaagccgcgu      780

ccauauacug ccgcaaacuu cgccuccacc aaaugauaga acucuccuca aaagccgcug      840

ucaacgggua cuccgguagc gacacagucg gcgccggcuu cacacaagcc aaggagcaca      900

uacgccgcaa ccgccaaucg cgaacauucc ucgucgagaa cgucaucgga gaaaucuggu      960

cagaacucga agaaggcgac aaauacgugg uagucgacag cggcggcgga accguggacc     1020

uaaccgucca ccagauacgc cugccagaag ggcaccuuaa agaauuguac aaagccacag     1080

gaggacccua cggaucauua ggagucgacu acgaguucga aaagcugcuc uacaaaaucu     1140

ucggcgaaga uuucauugaa caauucaaaa uaaaacgccc cgccgcaugg gucgaucuga     1200

ugauagccuu cgaaucacgu aaacgcgcag ccgcucccga ccgaaccaau ccacucaaca     1260

ucacccuacc cuucucauuc aucgacuacu auaagaaauu ccgcgggcac uccgucgaac     1320

augcucuccg aaaaucaaac gucgauuucg ucaaaugguc aucccaaggc augcuccgca     1380

ugucaccgga cgccaugaac gcacuauuca aacccacuau agacucaaua aucgaacacc     1440

uacgcgaccu cuuccaaaag cccgaaguaa gcacagucaa auuccucuuc cucgugggcg     1500

gguucgccga agccccacuc cuccaacagg ccguccaggc cgcauucgga gaccagugcc     1560

guaucauaau cccacaagac guaggccuaa ccauacucaa aggcgcaguc cuauucggcc     1620

uagaccccgc cgucauuaag guccgccguu cccccuuaac auacggaguc ggcguccuua     1680

accgcuaugu cgaaggaaaa cacccacccg aaaagcuccu agucaaggac ggcacccgau     1740

ggugcaccga cgucuucgac aaauucauau ccgcagacca aagcguugca cucggcgaac     1800

uugucaaacg aucauacacc cccgcgaaac ccucacaauu agucauaguc auaaacaucu     1860

acuccucaga acacgacaac guuuccuuca ucaccgaccc cggcguaaag aaaugcggaa     1920

cccucagacu ggaccucacc ggcacauccg gcacugccgu acccgcacga cgcgaaauac     1980

aaacccucau gcaguucggc gacaccgaaa ucaaagcaac ugccaucgac auagccacau     2040

caaaauccgu aaaaguagga aucgacuucc uaaacuacua aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  3485
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt9)

<400>  3485
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcuag       60

caguccccga aaugggccua caaggccucu acaucggcuc cagccccgaa cguucacccg      120

uacccucacc accaggcuca ccaagaaccc aagaaaguug cggcaucgcc ccacucacgc      180

ccucccaauc ccccaagccc gaaguccgag caccccaaca ggcuucauuc ucugucgucg      240

uagcaauaga cuucggaacc accucuagcg gcuacgcuuu cucauucgcc agcgaccccg      300

aagccaucca caugaugcgc aaaugggaag gaggagaccc cgguguagca caccagaaaa      360

ccccaaccug ccuacuccuc acacccgaag gagccuucca cagcuucggc uacaccgccc      420

gagacuacua ccacgaccuc gaccccgagg aggcucguga cuggcucuac uucgaaaaau      480

ucaaaaugaa aauccacucc gccaccgacc ucacccucaa aacucaacua gaagcgguua      540

acggaaaaac aaugcccgcc cuagaaguuu ucgcacacgc ccugcgcuuc uuccgagaac      600

acgcacucca agaacuucgc gaacaaagcc cgagccuucc ugaaaaagac accguucgau      660

gggucuugac aguccccgca auauggaaac aaccggcgaa acaauucaug cgagaagcag      720

ccuaccuagc cggacuggua ucccgagaaa acgccgagca acuacucauc gcacucgaac      780

ccgaagcugc auccgucuac ugccgcaaac uacgccucca ccaacuccuc gaccuguccg      840

gccgcgcacc aggaggcggu agauugggug agcgacgcag uauagacagu uccuuucgac      900

aagcacgcga acagcuacgc cgaagccggc acucccgaac uuuccuugua gaaucaggcg      960

ucggcgaacu cugggccgaa augcaagcag gagacagaua cguaguugcg gacugcggcg     1020

gcggcaccgu ugaccugaca guccaccaau uagaacaacc acacggcacu cucaaagaac     1080

uuuacaaagc auccggcgga cccuauggcg ccguaggagu cgacuuagca uuugaacaac     1140

uccugugcag aaucuucggg gaagacuuua uagcaaccuu caaaagacaa agacccgcag     1200

ccugggucga ccuuaccauc gcauucgaag cacggaaacg aacagccggc ccacaccgag     1260

caggagcccu gaacaucagc cuaccauucu cauucaucga uuucuaccgg aaacaacgcg     1320

gccacaacgu cgaaacagcc cuccggcgaa gcagcgucaa cuucgucaaa uggucauccc     1380

aaggaaugcu acgaaugucc ugcgaagcaa ugaacgaacu cuuccaacca accgucucgg     1440

gcaucaucca acacaucgaa gccuuacuag cccgcccaga aguacaagga gucaaacucc     1500

ucuuccuagu cggaggcuuc gcagaguccg caguccuaca acacgcgguu caggccgccu     1560

uaggagcacg cggccuccga gucgugguac cccacgacgu aggccucaca auccuaaaag     1620

gcgccguucu cuucgggcaa gcucccggcg ucguacgcgu acgccgcagc ccacuaaccu     1680

acggcguugg cguacucaac cgcuucgucc cgggaagaca cccacccgaa aaacuccuag     1740

uccgagacgg uagacgcugg ugcaccgacg ucuuugaaag auucguggcc gccgaacaau     1800

cagucgcccu cggcgaagaa guccgacgca gcuacugccc cgcacgcccc ggccaacgac     1860

gcguccucau caaccuauac ugcugcgcag cagaagacgc acgcuuuaua accgaccccg     1920

gcguccgaaa augcggcgca cucucacucg aauuagaacc cgcagacugc ggucaagaca     1980

ccgccggagc cccgcccgga agacgagaaa uccgcgccgc aaugcaauuc ggcgacaccg     2040

aaaucaaagu cacagccguc gaugucucca caaaccgaag cguaagggcc ucgauagacu     2100

uccuaaguaa cuagggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  3486
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt9)

<400>  3486
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcaa       60

gagaaaugac aauccuuggc uccgccgugc uaacccuccu acuagccggu uaccucgccc      120

aacaguaccu accccucccc accccaaaag ucaucggaau cgaucucggc accaccuacu      180

gcucagucgg cgucuucuuc cccggcaccg gaaaaguaaa aguuauaccg gacgaaaacg      240

gccacaucuc cauccccuca auggucuccu ucaccgacaa cgacgucuac gucggcuacg      300

aaagcgugga acucgccgac uccaaccccc aaaauacaau auacgacgcc aaacgcuuca      360

ucggcaaaau cuucaccgcc gaagaacucg aagccgaaau aggccgcuac ccuuucaaag      420

ugcucaacaa aaacggcaug gucgaguucu ccgucaccag caacgaaaca auaacaguau      480

cgccagaaua cgucggcucc cgccuccucc uuaaacuaaa agaaauggca gaagccuacc      540

uaggcaugcc cgucgccaac gcaguaaucu cagucccagc cgaguucgac cuuaaacaaa      600

ggaacuccac caucgaagca gcuaaccucg ccggccugaa aauccuccga gucaucaacg      660

aacccaccgc cgcggccaug gcauacggac uucacaaagc cgacgucuuc cacguccucg      720

uaaucgaccu gggcggcggc acccuagacg ucagccuucu caacaaacag ggaggcaugu      780

uccucacacg cgcgauguca ggaaacaaca aacuaggagg ccaggacuuc aaccaacgcc      840

uacuccaaua ccuauacaaa caaauauacc aaaccuacgg auucguucca ucccgaaaag      900

aagaaaucca cagacuccga caagcaguag aaaugguaaa acucaaccua acccuacacc      960

aauccgcaca acuaagcguc cuccuuacag uagaagaaca agaccgaaaa gaaccacacu     1020

ccuccgacac cgaacucccc aaggauaagc uauccagcgc ugacgaccac agaguaaacu     1080

ccgguuucgg ccguggccuc agcgacaaga aaucugguga aucacagguc cuauucgaaa     1140

ccgagauauc ccgaaaacuc uucgacaccc ucaacgaaga ccucuuccag aaaauccucg     1200

uccccaucca acaaguccuc aaagaaggcc accucgagaa aacagaaauc gacgaagucg     1260

uacucguagg aggcuccaca cgcauccccc gcauccgaca aguaauccaa gaguucuucg     1320

gcaaagaccc caacaccuca guagacccug accuggccgu cguaaccgga gucgccaucc     1380

aggccggaau ugauggcgga uccuggcccc uacaagugag cgcccucgaa aucccaaaca     1440

aacaccucca gaaaacaaac uuuaacugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3487
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt9)

<400>  3487
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

caauaggcgu ccaccuaggc ugcaccagcg ccugcgucgc cgucuacaaa gacggcagag      120

caggcguagu cgccaacgac gccggagacc gcgucacccc agcagucguc gccuacagcg      180

agaacgaaga aaucgugggg cucgcagcca aacaaucccg cauccgaaau aucuccaaca      240

cagucaugaa aguaaaacaa auccuaggac gcaguucguc agauccccag gcccaaaaau      300

acauagccga aucaaaaugc cuaguaauag agaaaaacgg caaacuccga uacgaaaucg      360

acaccgguga agaaacaaaa uucguaaacc cagaagacgu cgcacgccua auauucagca      420

agaugaaaga aaccgcccac ucugugcucg gaagugacgc caacgacgua gucaucaccg      480

uaccauucga cuucggcgaa aaacagaaaa acgcccuagg cgaagccgca agagccgccg      540

guuucaacgu ccugcgacuc auacacgaac caagcgccgc gcuccucgcc uacggcaucg      600

gccaagacuc cccaaccggg aaguccaaca uccuaguauu caagcuagga ggcaccaguc      660

uaucccuauc cgucauggaa gucaacagcg gcauauaccg cguacucuca accaacacag      720

acgacaacau cggcggagcc cauuucaccg aaacacuagc ccaauaccuc gccuccgagu      780

uccaacgcuc uuucaaacac gacguccgcg gcaacgcgcg cgccaugaug aaacuaacca      840

acagcgccga aguagcuaaa cacucacucu caacacucgg cuccgcaaac ugcuuucuug      900

acagccuaua cgaaggccaa gacuucgacu gcaacgucuc aagagccagg uucgaacuac      960

uaugcucacc acucuucaac aaaugcaucg aagccauacg uggacuacuc gaccaaaacg     1020

gauucacugc cgacgacauc aauaaaguag uacucugcgg aggaucuuca cgaauaccua     1080

aacuacaaca acucaucaaa gaccucuucc cagccgucga acuucuuaac uccaucccac     1140

ccgacgaagu cauccccauc ggcgccgcca ucgaagccgg cauccucauc ggaaaagaaa     1200

accuacuugu agaggacucc cucaugaucg aaugcuccgc cagagacauc cuagucaaag     1260

gcguagacga gagcggcgcc agccgauuca ccguccuauu ccccuccgga acaccacuac     1320

cagcccgacg ccaacacaca cuacaagccc caggaucaau auccuccguc ugccucgaac     1380

ucuacgaaag cgacggcaaa aacuccgcaa aagaagaaac caaauucgca caagucgucc     1440

uccaagaccu cgacaagaaa gaaaacggcc uccgcgacau cuuagcagug cucaccauga     1500

aacgcgacgg cagccugcac guaacaugca cagaccagga aaccggcaaa ugcgaagcca     1560

ucuccauaga aaucgccuca uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  3488
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt9)

<400>  3488
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uaguaggacu cgacguaggg agccaauccu gcuacauagc cgucgcccgc gccgguggca      120

ucgaaaccau cgcaaacgag uucagugacc gaugcacccc cuccguaaua uccuucggaa      180

gcaaaaacag aaccauaggc guagcugcua aaaaucagca aaucacacac gcgaauaaca      240

cggucucaaa cuucaaacga uuccacggca gagccuucaa ugaccccuuc auccaaaaag      300

aaaaagaaaa ccuaucauac gaccuaguac cccucaaaaa cggaggcgua ggaaucaaag      360

ucauguacau gggagaagaa caccuauuca gcguagaaca aauaacugcc augcuacuca      420

ccaaacucaa ggaaaccgca gaaaacucac ugaaaaagcc agucaccgac ugcgugauaa      480

gcguccccuc uuucuucacc gacgccgaac gccgaucggu ccuagacgca gcccaaauag      540

ucggccuaaa cugucuacga cuaaugaacg acaugacagc aguggcccug aacuacggca      600

ucuauaagca agaccugccc ucgcucgacg aaaaaccacg caucguagua uucgucgaua      660

ugggccacuc agcauuccaa gugucagccu gcgcauucaa caagggcaaa cucaaagugc      720

uaggcaccgc cuucgacccc uuucucggag gcaaaaacuu cgacgaaaag cuaguggaac      780

acuucugcgc agaauuuaaa accaaauaua aacucgacgc caaauccaaa aucagagccc      840

ugcuacgacu cuaccaagaa ugcgaaaaac uaaagaaacu gauguccucc aacucaaccg      900

accugccccu gaacaucgaa ugcuucauga acgacaaaga cgucuccggg aaaaugaaca      960

gaucacaauu cgaagaacuu ugcgccgaac uacuccagaa aaucgaagua ccacucuacu     1020

cccuccugga acaaacccac cuaaaagucg aagacguguc cgccguagaa auugucggcg     1080

gcgcaacacg cauaccggcc guaaaagaac gaauagcgaa auucuucggc aaagacaucu     1140

ccaccacccu uaacgcagac gaagccgucg cacgcggcug cgcccuccag ugcgcaauac     1200

ucucgccggc cuucaaaguc cgcgaguucu ccgucacgga ugccguccca uucccgaucu     1260

cccugauuug gaaccacgac agcgaagaca cugaaggagu ccaugaggua uucagccgaa     1320

accacgcagc ucccuucagc aaaguacuca cauuccuacg ccgcggacca uucgaacugg     1380

aagcguucua cagugacccc cagggaguac cguacccgga agcaaaaauc ggacgcuucg     1440

uggugcaaaa cguaucagca caaaaggacg gcgagaaaag ccgcgucaaa guaaaaguaa     1500

gaguaaauac gcacggaauc uucacaaucu caacagccuc aauggucgaa aaaguaccca     1560

ccgaggaaaa cgaaaugagc uccgaagccg auauggaaug ccucaaccaa cgcccacccg     1620

aaaaccccga uacagacaag aacguccaac aagacaauuc cgaagcgggc acacaacccc     1680

agguccaaac agacgcacag caaacaagcc aguccccacc cucacccgag cucaccucgg     1740

aagagaacaa aauacccgau gccgacaaag cuaacgagaa aaagguggac caaccacccg     1800

aagccaagaa acccaaaauc aaagucguua acguagaacu accaauagaa gccaaucuug     1860

uauggcagcu cgggaaagac cuccugaaua uguacaucga aacagaaggc aaaaugauca     1920

ugcaggacaa acucgaaaaa gaacgaaacg augccaaaaa cgccgucgaa gaauacguau     1980

acgaguuccg agacaaacua ugcggccccu acgaaaaguu caucugcgaa caagaccauc     2040

aaaacuuccu ccgacuccuc accgaaacag aagacuggcu auacgaagaa ggcgaagacc     2100

aagccaagca ggcguacgua gacaaacuag aggaacuaau gaaaaucggg accccuguaa     2160

aaguacgauu ccaagaagcc gaagaacgac caaaaauguu ugaagaacug ggacagcgcc     2220

uccagcacua cgccaagauc gccgcagacu uccgcaauaa agacgaaaaa uacaaccaua     2280

uagacgaaag cgaaaugaaa aaggucgaaa agagcgucaa cgaggucaug gaauggauga     2340

acaacgucau gaacgcucaa gccaagaaaa gucuagacca agaccccgua gugagggcgc     2400

aagaaaucaa aaccaaaaua aaagagcuga acaacacaug ugaaccaguc gucacgcaac     2460

cgaaaccaaa aaucgaaagc ccgaaacucg agcgcacacc caacggaccc aacaucgaca     2520

agaaagaaga agaccuagaa gacaaaaaca acuucggugc cgagcccccg caccaaaacg     2580

gugaaugcua ucccaacgag aaaaacagcg ugaacaugga ccuugacuaa ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  3489
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt9)

<400>  3489
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

acaaagugag acgacaacgu ccgcgucggc ggguuugcug ggcacucgug gcaguccucc      120

uagcagacuu gcucgcccua agcgauaccc uagcagugau gucuguagac uuaggaucgg      180

aaucgaugaa aguagccauc gucaaaccgg gagugccaau ggaaaucgua cuaaacaaag      240

aaucacgcag gaaaaccccc gugaucguca cgcugaaaga gaaugagcga uucuucggcg      300

auuccgcagc auccauggcg aucaaaaacc cgaaggcaac acugagauac uuucagcacc      360

uccucggaaa acaggcagac aacccacacg uagcccucua ccaagcacgc uuccccgagc      420

acgaacuaac auucgacccc caacgccaaa ccgugcacuu ccaaaucagc agucagcucc      480

aauuuagccc agaagaggua cucggaaugg uacucaacua cuccaggagc cucgcugaag      540

auuuugccga acagcccaua aaagacgcag ucauaacagu acccgucuuc uucaaccaag      600

ccgaaagacg agcgguacuc caagcagcaa gaauggccgg ccucaagguc cuucaacuga      660

ucaacgacaa cacagcgaca gcacucuccu acggaguauu cagaagaaaa gacauaaaca      720

ccacagcaca gaacaucaug uucuacgaca ugggaagcgg aaguacuguu ugcacaauag      780

uaaccuacca aaugguaaag accaaagagg caggaaugca accacaacuu caaauacgag      840

gggucggcuu ugacaggacu cuaggaggac uggagaugga acuccggcuu cgagaacgcc      900

uagcaggacu cuucaacgaa caacgaaagg gccagagagc caaagacgua cgagaaaauc      960

cacgagcaau ggccaaacuc cuaagagaag cgaaccgacu caaaacgguc cuaagcgcaa     1020

acgcggacca cauggcccaa aucgaaggac uaauggacga cguugacuuc aaagccaaag     1080

uaacacgagu agaguuugaa gaacucugcg ccgaccucuu cgaacgagug ccaggaccgg     1140

uacaacaagc acuccagagc gcagaaaugu cccuagacga aaucgagcaa gugauccuag     1200

uaggaggcgc aacccgggua ccacgcguac aagaaguauu acugaaagcg gugggaaaag     1260

aagaguuagg gaaaaacaua aacgccgacg aagccgcagc aaugggagca guauaccaag     1320

ccgcggcccu cagcaaagcc uucaaaguaa aacccuucgu agugcgggac gcagucguau     1380

acccaauacu gguggaguuu accagagaag ucgaagagga acccggcauc cacagccuaa     1440

aacacaacaa aagaguccug uucuccagga ugggacccua cccacaacgc aaggugauaa     1500

cauucaaccg auacagucac gacuuuaacu uccacauaaa cuauggggac cugggcuucc     1560

uaggacccga ggaccuccgc gucuucggau cccaaaaccu aacaaccgua aaacucaaag     1620

gaguaggaga cucuuucaaa aaguaccccg acuacgaauc aaaggggaua aaagcccacu     1680

uuaaccucga cgaaaguggg guccucagcc uggaccgcgu agagucgguc uucgaaacac     1740

ucgucgaaga cagugccgaa gaagaaucaa cccuaacgaa acuaggcaac acaauaucaa     1800

gccucuucgg aggaggcaca acaccugacg ccaaagaaaa cggaacagac accguacaag     1860

aagaagagga aagccccgcg gagggaucaa aagacgaacc aggcgaacag guggaacuca     1920

aagaagaagc ggaagcccca gucgaggaug gaagccaacc cccaccaccc gaaccgaaag     1980

gcgacgcaac accggaaggc gaaaaggcca ccgagaaaga aaacggggac aagucagaag     2040

cccaaaagcc aagugaaaaa gccgaagcag gcccagaagg aguagccccg gccccagaag     2100

gagagaaaaa gcagaaaccc gccaggaaac gccgaauggu ggaggagaua ggcgucgaac     2160

ucguaguacu ggaucuacca gaccuccccg aagauaagcu agcacaaagc gugcaaaaac     2220

uccaggaccu cacccugcgc gacuuagaaa aacaagagag agagaaagca gcaaacagcc     2280

uggaggccuu caucuucgaa acacaagaca agcuguacca gcccgaauac caagaaguga     2340

gcacggaaga acaaagagaa gagaucuccg gcaagcuauc cgcagccagc acguggcucg     2400

aagacgaagg aguaggggcc acaacaguua ugcucaaaga aaaauuagca gaacuaagaa     2460

agcuaugcca aggacuauuu uucagagugg aagagagaaa gaaauggccg gaaaggcuca     2520

gugcccucga caaccuacuc aaccauucca gcauguuccu gaagggcgca aggcuaauac     2580

cagaaaugga ccaaauauuc acagaaguag aaaugaccac ucucgagaaa guaauaaacg     2640

agacaugggc guggaaaaac gcaacccucg cagaacaagc gaagcugcca gccacggaga     2700

agccgguucu acucagcaag gauauagaag caaagaugau ggcacuagac agagaagucc     2760

aguaccuguu aaacaaagca aaauucacaa aaccacgccc aaggccgaaa gacaaaaacg     2820

gaacacgagc agaaccacca cugaacgcgu cagcuucaga ccaaggagaa aaaguaauac     2880

ccccagcagg gcaaaccgag gacgcagaac caaucaguga accagagaaa guugagacgg     2940

gaagcgaacc aggagacacg gaacccuuag aauuaggagg cccaggcgca gaaccagaac     3000

aaaaagagca aagcacuggc caaaagcguc cccucaaaaa cgacgagcua ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3490
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt9)

<400>  3490
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aagagacgca aacgcaagau caaccgaugg aggaggaaga aguggaaacc uucgcguucc      120

aggcagaaau cgcgcaacug augagccuca uaaucaacac guuuuacagc aacaaagaaa      180

uauuccugcg cgagcuaaua agcaacagca gcgacgcacu cgacaagaua cguuacgaau      240

cccuaacgga cccgagcaaa cuagacagcg ggaaggaacu acacaucaac cucaucccca      300

acaagcagga ccgaacccug accauagucg acaccggaau agggaugacg aaagcagacc      360

ucaucaacaa ccucggaacg aucgccaaaa gcggcacgaa ggcuuucaug gaagcacuac      420

aagcgggcgc cgacauaagu augauaggcc aauucggagu aggauucuac agugccuacc      480

uaguggcaga gaaagucacc guaauaacaa aacacaacga cgacgaacaa uacgccuggg      540

aaagcagcgc cgggggcucc uuuacaguaa gaacagacac cggagaacca augggccgcg      600

gaacaaaagu aauacuccac cuaaaagagg accaaacaga auaccucgag gaaagacgaa      660

uaaaggagau cgucaaaaag cacagccaau ucauaggaua cccaauaacg cuauucgugg      720

aaaaagaacg agacaaagaa gugucagacg acgaagcgga ggaaaaagag gauaaggaag      780

aagagaaaga gaaagaagaa aaagaaagcg aagacaagcc agaaaucgag gacguagggu      840

cggacgaaga ggaggaaaag aaagacggcg auaagaaaaa gaaaaagaaa aucaaagaaa      900

aguacaucga ccaagaggag cuaaacaaaa caaaaccgau cuggacacga aacccagacg      960

acaucacgaa cgaggaauac ggcgaguucu acaaaucacu cacaaacgac ugggaagacc     1020

aucuagcagu aaagcacuuc agcgucgaag gccaacugga guucagagcu cuccuguucg     1080

uacccaggcg cgcccccuuc gaccucuucg aaaacagaaa gaagaaaaac aacauaaaau     1140

uauacguaag acgaguauuc auaauggaca acugcgaaga acugaucccg gaauaccuca     1200

auuucauccg cggagucgua gacagcgagg accuaccacu aaacauaagc agagagaugc     1260

uacagcagag uaaaauccua aaaguaauac ggaaaaaccu ugucaaaaag ugccuggagc     1320

uauucaccga acuugcagag gacaaagaaa acuacaagaa guucuacgag caguucagca     1380

agaauauaaa acuaggcaua cacgaagacu cacagaaccg caagaaacua agcgaacucc     1440

ugagauacua caccagcgcc agcggggacg agauggucag ccuaaaagac uacugcacaa     1500

gaaugaaaga aaaccaaaaa cacaucuacu auaucacggg agaaacaaaa gaccaggucg     1560

cgaacucagc cuucgucgag cgacuccgca aacacgggcu cgaaguaauc uauaugauag     1620

agcccauuga cgaguacugc guacagcaac uaaaagaguu cgaaggaaaa acccucguaa     1680

gcgucacgaa agaaggccua gaacugcccg aagacgaaga ggagaaaaag aaacaagaag     1740

aaaagaaaac aaaauucgaa aaccugugca aaaucaugaa agacauccug gagaagaaag     1800

uggagaaagu agucguaagc aaccgccuag uaacgagccc augcugcaua gucacaagca     1860

cauacggaug gacggcgaac auggagcgaa uaaugaaagc ccaagcccug cgagacaaca     1920

gcacaauggg auacauggcg gccaaaaagc accuagaaau caaccccgac cacuccauca     1980

ucgaaacacu cagacaaaaa gccgaagccg acaaaaacga caaaagcgua aaggaccugg     2040

ugauacuccu uuacgaaacc gcccugcucu caagcggcuu cucccuggag gacccacaga     2100

cccacgcgaa cagaaucuac agaaugauaa agcugggccu aggaauagac gaagacgacc     2160

caacagccga cgacacaucc gcagccguca ccgaagaaau gccaccccua gaaggggacg     2220

acgacacaag cagaauggaa gaaguagacu aaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  3491
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt9)

<400>  3491
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

caucaaaacu agacuccggc aaaggccuac acauaaaccu cguccccaac aaacaaaacc      120

aaacccucac caucguagac acacgcaucg gcaugaccaa aaccgaccuc aucaacaacc      180

ucggaaccgu caccaaaucc ggcacaaaag ccuucaugga agcccuccaa gcagacgcag      240

acauauccau gaucggccac uucggaguag gcuucuacuc cgccuaccuc gucgccaaaa      300

aagucaccgu caucucaaaa cacaacaacg acgaacaaua caccugggaa uccuccgcag      360

gaggcagcuu caccguccgc accgacgaau aaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  3492
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt9)

<400>  3492
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aggaaguaca ccacggagaa gaggaagucg aaaccuucgc cuuccaagcg gaaaucgccc      120

aacuaaugag cuugauaaua aacacguucu acuccaacaa agagauauuc cugcgggagc      180

uaauaucgaa cgccagcgac gcccuagaca agaucaggua cgagucccuc accgacccca      240

gcaaacuaga cucgggcaag gaacugaaaa ucgacauaau cccgaacccg caagagcgca      300

cccucacccu aguggacacg ggaauaggca ugaccaaagc agaccucaua aacaaccucg      360

gcaccauagc caagagcgga accaaggccu ucauggaagc acugcaagca ggagcagaca      420

uaaguaugau cgggcaauuu ggcguagggu ucuacucagc guaccucguc gccgaaaaag      480

uaguagucau aacgaaacac aacgacgacg agcaauacgc gugggaguca agcgcaggag      540

ggagcuucac cguacgggca gaccauggcg aacccauagg cagaggcacc aaaguaaucc      600

uccaccuaaa ggaagaccaa acagaguacc uagaagaacg gagaguaaaa gaagucguca      660

agaaacacuc ccaauucaua ggcuauccca ucacacuaua ccucgagaaa gaacgagaaa      720

aagaaauauc cgacgacgaa gccgaagaag aaaaagggga aaaagaagag gaagacaaag      780

acgacgaaga aaagcccaaa auagaagacg uuggcucgga cgaggaggac gacagcggca      840

aagacaagaa aaagaaaacg aagaaaauaa aagagaaaua caucgaucaa gaagaacuca      900

acaaaaccaa accgaucugg acacggaacc ccgacgauau cacgcaagag gaguacggcg      960

aguucuacaa aucacuaacg aacgacuggg aagaccaccu cgcggucaag cacuucagug     1020

uggaaggcca acuagaguuc cgagcgcuau uguucauccc aagacgcgca cccuucgacc     1080

ucuucgaaaa caaaaagaag aaaaauaaca uaaaacugua cguacgacgg guguucauca     1140

uggacagcug cgacgaauug auaccggaau accugaacuu cauccgagga gucguggacu     1200

cagaagaccu cccacuaaac aucucccgag aaaugcuuca acagagcaaa auccuaaaag     1260

ugaucaggaa aaacaucgua aagaaaugcu uagaacuauu cagcgaacua gcagaggaca     1320

aagaaaacua caagaaauuc uacgaagccu ucagcaaaaa cuugaaacua ggcauacacg     1380

aagacagcac gaaccgaagg cgcuuguccg aacuacuacg cuaccacacg ucccagagcg     1440

gcgacgagau gaccagccug agugaauacg ugagccgcau gaaagaaacg cagaaaagca     1500

uauacuacau aacaggcgaa agcaaagaac aaguagcgaa cagugccuuu gucgaaagag     1560

uacgaaaacg cggauucgag gucguauaca ugacggaacc aauagaugag uacugcgucc     1620

aacaacuaaa agaguucgac gggaaaagcc uagucagugu uacgaaagag ggccucgaac     1680

uacccgaaga cgaggaggag aaaaagaaaa uggaagaaag caaagcaaaa uucgaaaacc     1740

ugugcaagcu caugaaagaa auauuggaca agaaagucga aaaaguaacg aucucgaauc     1800

gacucguauc aucccccugc ugcauaguca cgagcacaua cggauggaca gcgaauaugg     1860

agcggaucau gaaggcacaa gcccuacgcg acaacagcac caugggcuac augauggcga     1920

agaaacaccu cgagauaaac ccagaccacc cgaucgugga gacgcuaaga cagaaagcag     1980

aagccgacaa aaacgacaaa gccguaaaag accuaguagu acugcuauuc gaaacagccc     2040

ugcucagcag cggauucuca cucgaagacc cgcaaaccca cagcaaccga aucuaccgca     2100

ugaucaagcu cggacucggc aucgacgaag acgaaguagc cgccgaagaa ccgaacgcag     2160

ccgucccuga cgagauaccg ccccucgaag gcgacgagga cgcaagccga auggaggaag     2220

uagacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  3493
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt9)

<400>  3493
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcgag       60

ccuuaugggu ccucggacuc ugcugcgugc uacugaccuu cggcagcgua agagcagacg      120

acgaggucga cguagacggc acgguagagg aagaccucgg caaaucgcga gaaggcucac      180

gcacagacga cgaaguaguc cagcgagaag aagaagcgau acaacuugac gggcugaacg      240

cgagccagau ccgcgaacuc agggagaaaa gugaaaaauu cgcauuucag gcagaaguua      300

acaggaugau gaagcuaauc auaaauuccc uguacaaaaa caaagagauc uuccuacggg      360

aacuaauauc aaacgccagc gacgcucuag acaaaaucag acuaauaagc cuaacagacg      420

aaaacgcacu aagcggaaac gaagaauuga cagucaaaau caagugcgac aaagagaaaa      480

accugcugca cgucaccgac acaggcgugg gcaugacccg agaggaacuc gucaaaaacc      540

ugggaacgau agcaaaguca gggaccagcg aguuccucaa caaaaugaca gaagcccagg      600

aggacgggca gagcacgagc gaacugauag ggcaauucgg aguaggauuc uacagcgcgu      660

uccugguagc ggacaaaguc auagucacca gcaaacacaa caacgauacc cagcacaucu      720

gggagagcga caguaacgaa uuuagcguaa ucgcagaccc ucgaggcaac acacuagggc      780

gagggaccac aauaacacug guacuaaagg aagaagccag ugacuaccuc gagcuagaua      840

ccaucaagaa ucucguaaag aaauacucac aauucaucaa cuucccaauc uacgucugga      900

gcagcaaaac agaaacgguu gaagaaccua uggaggaaga ggaagcggca aaagaggaaa      960

aggaagaauc agacgacgag gccgccgugg aagaggaaga agaggaaaag aaaccaaaaa     1020

cgaagaaagu ggagaaaaca guaugggacu gggaacugau gaacgacauc aagcccauau     1080

ggcaaagacc aagcaaggaa guagaagaag acgaguacaa ggcguucuac aaaaguuucu     1140

ccaaggaguc agacgacccc auggcauaua uacacuucac ggcagagggc gaagucacau     1200

ucaagagcau acucuucgug cccaccucgg caccacgcgg acuauucgau gaguacggga     1260

gcaagaaaag cgacuacaua aaacuauacg ucaggagggu auucauaacg gacgacuucc     1320

acgacaugau gcccaaguac cugaacuucg ucaagggagu agucgauagc gaugaccuac     1380

cccugaacgu aagcagggaa acccuacaac aacacaaacu ucucaaagua auccggaaaa     1440

agcucgugag gaagacccua gacaugauaa agaaaauagc ggacgacaaa uacaacgaca     1500

cauucuggaa agaguucggg acaaacauaa aacuaggugu gauagaggac cacagcaaca     1560

ggacgagacu ggccaaacuc cuacgauucc aaucaagcca ucaccccaca gacaucacga     1620

gccuagacca guacguagaa agaaugaagg aaaaacagga caaaauuuac uucauggcag     1680

gguccagcag aaaagaggcc gaaagcuccc ccuucgucga aaggcugcuc aagaaagggu     1740

augaagucau auaccuaaca gagccagucg augaauacug cauacaggca cugccagagu     1800

uugacggcaa gagauuccaa aacgucgcaa aagaaggagu gaaauucgac gaaagugaga     1860

agaccaaaga gagcagagaa gccgucgaga aagaguucga accucuccuc aacuggauga     1920

aagacaaagc gcuaaaagac aagauagaaa aagcagucgu aagccaacga cucacagaaa     1980

gcccaugcgc gcuagucgcc ucgcaauacg gauggucagg gaacauggaa agaaucauga     2040

aagcgcaagc guaccaaacu gggaaagaca uauccacgaa cuacuacgcc agccaaaaga     2100

aaacguucga aaucaacccc aggcauccac ugauaaggga uaugcuacgc agaauaaaag     2160

aagacgagga cgacaaaaca guccucgacc ucgcagucgu ccucuucgaa acggcaaccc     2220

uuagaagcgg cuaccugcug ccagacacca aagccuacgg agacaggauc gagcgaaugc     2280

uacgacucuc acuaaacaua gacccggacg caaaaguaga ggaagaaccg gaggaggagc     2340

cagaagaaac agccgaagau acaacagagg acacggaaca agacgaagac gaagaaaugg     2400

acguagguac agacgaggaa gaagaaacag ccaaagagag cacagcggag aaggacgagc     2460

uauagggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  3494
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt9)

<400>  3494
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

gagaauuaag agcccuauua cucuggggac gucgucuccg uccccuccuc cgcgcaccag      120

cccuagcagc cguacccggc ggcaaaccca uucucugccc aagaagaacc acugcccagc      180

uagggccccg acgaaacccc gcguggucgc uccaagcugg acgacucuuc ucaacccaaa      240

ccgcagaaga caaagaagaa ccccuccaca gcaucauauc uucaacagaa uccguccaag      300

guagcacauc caaacacgag uuccaagccg aaaccaagaa acuguuagau aucgucgccc      360

gcucccucua cagcgaaaaa gaagucuuca uccgcgaacu gaucucaaac gccagcgacg      420

cccuagagaa acuacgccau aagcuagucu cagacggcca agcacuaccc gaaauggaaa      480

uucaccucca aaccaacgcc gaaaaaggca ccauaacaau ccaagacacc ggaaucggca      540

ugacccaaga ggaacucgua agcaaccucg gcacuaucgc gcgcucaggg ucaaaagcau      600

uccuagacgc uuuacaaaac caggccgagg cuucauccaa aauaaucggc caauucggcg      660

uaggcuucua cucagccuuc auggucgcgg aucgcgucga agucuacucc cgcagcgcag      720

ccccagggag ccuaggguac caguggcuca gcgacggcuc cggcguauuc gaaaucgccg      780

aagccuccgg agucagaaca ggaaccaaaa ucauaauuca ccugaaaucu gacugcaaag      840

aguucagcuc cgaagcacgc guucgagacg uagucacaaa auacuccaac uucgucuccu      900

ucccacucua ccucaacgga agacgcauga acacccucca ggccaucugg augauggacc      960

ccaaggacgu ccgugaaugg caacacgaag aguucuaccg auacguggca caagcccacg     1020

auaaaccacg uuacacccua cacuacaaaa ccgacgcccc acucaacauc agaagcaucu     1080

uuuacguccc cgacaugaaa ccgucaaugu ucgacgucuc ccgugaacua ggauccuccg     1140

ucgcacucua cucacgcaaa guccuaaucc aaacuaaagc cacagacauc cuucccaaau     1200

ggcuccgguu cauacgcggc gucguggacu cagaagacau cccccuaaac cucucccgcg     1260

aacuacucca agaauccgcg cuaauccgaa aacuuagaga cguacuacaa caacggcuaa     1320

ucaaauucuu caucgaccag aguaagaaag acgccgaaaa auacgcuaaa uucuucgaag     1380

acuacggacu auucaugcga gaaggcaucg ucaccgccac cgaacaagaa gucaaagaag     1440

auaucgcaaa acuccuacgc uacgagucuu ccgcccuacc cucaggacaa cuuaccucac     1500

uaagcgaaua cgccagccgc augcgcgcgg gcacacggaa uauauacuac cuaugcgcac     1560

ccaaccgaca ucucgccgaa cacagcccau acuaugaagc caugaagaag aaagacacug     1620

aaguccuauu cugcuucgaa caauuugaug agcucacccu acuacaccuc cgggaauuug     1680

acaaaaagaa acuaauaucc gucgagaccg acaucgucgu agaccacuac aaagaggaaa     1740

aauucgagga ccgcucccca gcagccgagu gccuaagcga aaaagaaacc gaagaacuaa     1800

uggccuggau gcgcaacguu cuaggcucaa gaguaaccaa cguaaaagua acccuacgac     1860

ucgacaccca ccccgccaug guaaccguac ucgaaauggg agcagcccgc cacuuccuac     1920

gaaugcaaca acucgccaaa acacaggagg aacgagccca gcuccuacag ccaacacucg     1980

aaaucaaccc ccgacacgca cucaucaaga aacucaacca acuccgggca uccgaaccag     2040

gacucgccca gcuccuagua gaccagaucu augaaaacgc caugaucgcu gcaggccuag     2100

ucgacgaccc aagagcaaug guuggacgac uaaacgaacu gcucgucaaa gcccucgagc     2160

gccacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  3495
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt9)

<400>  3495
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

aaaucuccuc ccuacccacc caacuauuca aaugcugcuu cugcgacuuc cuaaaaguca      120

aaaugcacac aauguccuca ucccacuuau ucuaccucgc acucugccuc cucacauuca      180

ccucauccgc caccgcaggc cccgaaaccc uaugcggcgc cgaacucguc gacgcacucc      240

aauucgucug cggcgaccgc ggcuucuacu ucaacaaacc cacaggcuac ggcuccuccu      300

caagacgagc accccaaacc ggcaucguag acgaaugcug uuuccgauca ugcgaccuuc      360

gccgccucga aauguacugc gcaccccuca aacccgccaa aucagcccgc uccguccgug      420

cccaacgaca caccgacaug cccaaaaccc aaaaagaagu ccaccucaaa aacgccuccc      480

gcggcuccgc aggcaacaaa aacuaccgca uguaaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  3496
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt9)

<400>  3496
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

uccccauggg caaaucaaug cucguccucc ucaccuuccu cgccuucgcc uccugcugca      120

uagccgccua ccgacccucc gaaacacucu gcggcggaga acucgucgac acccuacaau      180

ucgucugcgg cgaccgaggc uucuacuucu cccgacccgc cucacgagua ucccgccgcu      240

cccgcggcau cgucgaagaa ugcugcuucc gcucaugcga ccucgcccuc cucgaaaccu      300

acugcgccac cccagccaaa uccgaacgag acgucuccac cccacccaca guacuucccg      360

acaacuuucc ccgauacccc guaggcaaau ucuuccaaua cgacaccugg aaacaaucaa      420

cccaacgacu ccgccguggc cuccccgccc uacuccgcgc acgccgcgga cacguccuag      480

caaaagaacu cgaagccuuc cgcgaagcca aacgacaccg cccccucauc gcccucccca      540

cccaagaccc cgcccacgga ggcgccccac ccgaaauggc cuccaaccgu aaauaaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  3497
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt9)

<400>  3497
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

ccuucuccac cuccgccuuc ggccccgucg ccuucucccu cggccuccuc cucguccucc      120

ccgccgccuu ccccgccccc gucccccccg gcgaagacuc caaagacguc gcugcccccc      180

accgccaacc ccuaaccucc uccgaacgca ucgacaaaca aauccgcuac auccuagacg      240

gcaucucugc acuccgaaaa gaaaccugca acaaaucuaa caugugcgaa uccuccaaag      300

aagcccuagc cgaaaacaac cucaacuuac ccaaaauggc cgaaaaagac ggcugcuucc      360

aauccggcuu caacgaagaa accugccucg ucaaaaucau caccggccuc cucgaauucg      420

aagucuaccu cgaauaccua caaaaccgau ucgaauccuc agaagaacaa gcccgagccg      480

uccaaauguc caccaaaguc cucauccaau uccuccaaaa aaaagccaaa aaccucgacg      540

ccaucaccac accugaccca accaccaacg ccucacuccu cacaaaacuc caagcccaaa      600

accaauggcu ccaagacaug acaacacacc ucauccuccg cuccuucaaa gaauuccuuc      660

aauccucccu cagagcccuc cgccaaaugu aaggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  3498
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt9)

<400>  3498
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

uacucuggcu acgcggcuuc cuacuagcaa gcugcuggau cauaguaaga agcucaccca      120

ccccaggaag cgaaggacac agcgccgcgc cagacugccc aucaugcgca cucgccgccc      180

uccccaaaga cguacccaac agccagcccg aaaugguaga agcagugaaa aaacacauac      240

uaaacaugcu ccaccuaaaa aagcgacccg acguaaccca acccguccca aaagcagcac      300

uacuaaacgc aaucagaaaa cuccacguag ggaaagucgg cgaaaacgga uacguagaaa      360

ucgaagacga cauaggaagg cgcgccgaaa ugaacgaacu cauggaacaa acgucggaaa      420

uaaucacauu cgcagaauca gguacggcca gaaaaacccu acacuuugag aucagcaaag      480

aagggagcga ccuaagcguc gucgaaagag cagaggucug gcuguuccuc aaaguuccaa      540

aagccaacag aacacgcaca aaaguaacaa uacgccuauu ccagcaacaa aaacacccac      600

aaggcagccu agacaccgga gaagaggccg aggaaguagg acuaaaagga gaacggagcg      660

aacuacuacu aagcgaaaaa gucguagacg cccgcaaaag cacauggcau guauuccccg      720

uaagcagcuc cauacaacga cuccuagacc aaggcaaauc aucacucgac guaagaaucg      780

cgugcgaaca augccaagaa agcggagcca gccuuguacu acugggcaag aaaaaaaaaa      840

aagaagagga aggcgaaggg aaaaaaaaag gcggcggaga aggaggcgcc ggagcagacg      900

aagaaaaaga acaaagccac agacccuucc uaaugcugca agcacgacag agcgaagacc      960

acccccaccg cagacgccga cgcggacucg aaugcgacgg aaaaguaaac aucugcugca     1020

agaaacaauu cuucgucagc uucaaggaca uaggauggaa cgacuggaua auagcaccga     1080

gcggcuacca ugcaaacuac ugcgaaggcg aaugcccaag ccacaucgca ggcacaagcg     1140

gaagcagccu aagcuuccac agcaccguca ucaaccacua cagaaugcga ggacacagcc     1200

cauucgccaa ccugaaaagc ugcugcgucc cgacgaaacu aagaccaaug agcaugcuau     1260

acuacgacga cggccaaaac auaauaaaga aagacauaca aaacaugaua guagaagagu     1320

gcggcugcag cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  3499
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt9)

<400>  3499
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacg       60

gccuccccgg ccgagcacua ggcgccgcau gccuccuccu acucgcagcc ggauggcuug      120

gccccgaagc auggggcucc ccaacaccac cucccacccc cgcagcacca cccccacccc      180

caccacccgg cucccccggc ggcagccagg acacaugcac cucaugcggc ggcuuccgac      240

gccccgaaga acucggccgc gucgacggag acuuccucga agccguaaaa cgccacaucc      300

uuucccgccu ccaaaugcga ggccgaccca acaucacuca ugccgucccc aaagccgcca      360

uggucaccgc ccuacgcaaa cuccacgccg gcaaaguccg agaagacggc cgcgucgaaa      420

ucccccaccu cgacggccac gccagccccg gcgccgacgg ccaagaacga guuuccgaaa      480

ucaucuccuu cgccgaaacc gacggccuug cauccagccg aguacgccuc uacuucuuca      540

ucucaaacga aggcaaccaa aaccucuucg uaguacaagc cucccuuugg cucuaucuca      600

aacuccuacc cuacguacua gaaaaaggcu cucgccgcaa aguaagaguc aaagucuacu      660

uccaagaaca aggccacggc gaccgaugga acauggucga gaaacgcguc gaccuaaaac      720

gcuccgguug gcacacauuc ccccucaccg aagcaaucca agcccucuuc gaacgagggg      780

aacgccgccu caaccuagau guccaaugcg acagcugcca agaacuagcc gucguccccg      840

ucuucgucga ccccggcgag gaaucccacc gacccuucgu cgucguccaa gcacgacucg      900

gcgacucucg ccacagaaua cguaaacgag gacucgaaug cgacggccgc accaaccucu      960

gcugcagaca acaauucuuc aucgacuucc gccucauugg auggaacgac uggaucauag     1020

cacccacugg auacuacggc aacuacugcg aaggcuccug ccccgcauac cucgcaggag     1080

uccccggaag cgcauccucu uuccacaccg caguagugaa ccaauaccgc augcgcggcc     1140

ucaaccccgg aaccgucaac agcugcugca uccccaccaa acuuuccacc augagcaugc     1200

ucuacuucga cgacgaauac aacaucguaa aacgagacgu ccccaacaug auaguagaag     1260

aaugcggaug cgcauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  3500
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt9)

<400>  3500
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

uaaggguacu ccuccucacc gcccucacac ucugccacgg auucaaccuc gacacugaaa      120

acgcaaugac auuccaagaa aacgcgcggg gcuucggaca aucagugguc cagcugcaag      180

guagccgcgu cgucgugggc gccccgcaag agaucguagc agccaaccag cgcggcucuc      240

uauaucaaug cgacuacuca acuggcaguu gcgaacccau cagacuacaa gucccagucg      300

aagcugucaa caugagccuu ggacuaucgc uagccgcaac aaccucgccu ccucaacucc      360

ucgccugcgg cccaaccguc caccagaccu gcuccgagaa uaccuacguc aaaggccucu      420

gcuuuuuguu cggcucuaac cugcgccaac aaccgcaaaa auucccggaa gcccugcgag      480

gcugccccca ggaagacuca gacauagcuu uccuaauuga cggguccggc uccaucauac      540

cccacgacuu ccgucgaaug aaagaguucg uaucaacugu aauggaacaa cucaagaaau      600

cuaaaacgcu guucucacuc augcaauaca gcgaagaguu caggauccac uucaccuuca      660

aagaguucca aaacaaccca aacccacgcu cgcucgucaa gccaauaacc caacuccucg      720

gcagaaccca uacagcuaca ggcauccgaa aagucgucag agaacucuuc aacaucacca      780

acggcgcccg gaaaaaugcc uucaaaaucc uuguagucau caccgacggu gaaaaauucg      840

gcgauccucu uggauacgaa gacguaauuc cugaagccga cagagaagga gugauucgau      900

acgucaucgg agugggcgac gcauuccgca gugaaaaguc ccgacaagaa cugaacacca      960

ucgccuccaa accuccccga gaccacguuu uccaaguaaa caacuucgaa gcacucaaga     1020

ccauccaaaa ccaacugcgc gagaaaauau ucgcaaucga aggcacgcaa accgggucca     1080

guucauccuu cgaacacgaa augucccagg aaggauuuuc cgcagcgauc acuuccaacg     1140

gacccuuacu auccacaguc ggcucguacg acugggccgg cggcguauuc cuauacacca     1200

gcaaagaaaa auccaccuuc aucaacauga cccgggucga cagcgacaug aacgaugccu     1260

accucgggua ugcagccgca auuauacuaa ggaaccgcgu ucaaucccuc guacugggag     1320

caccccgcua ccagcacaua ggccuagugg cuauguuccg ucaaaacaca ggcauguggg     1380

aauccaaugc caacguuaag ggcacgcaaa uaggagccua cuucggcgcc ucucuaugcu     1440

ccguagacgu agacuccaac ggauccacag accuaguacu gaucggcgca ccccacuacu     1500

acgaacaaac cagaggcgga caagucucag uguguccacu cccccgcggu cgagcacgau     1560

ggcaauguga ugccguccua uacggcgaac agggacaacc guggggccgc uuuggagcug     1620

cccucaccgu ccucggcgau guaaacggug acaaacucac ugauguagcc auaggcgccc     1680

ccggagaaga ggauaacaga ggagccgucu accuauucca cggcaccuca ggaagcggga     1740

ucagcccauc ccacucccaa cgcauagcgg gcucaaagcu aucgccucgc cugcaguacu     1800

uuggccaaag ccucuccggc ggccaagacc ucaccaugga cggucuagua gaccucacag     1860

uaggagccca aggacaugua cuccuccuuc gcucgcagcc cguacucaga guaaaggcca     1920

ucauggaauu uaauccaaga gaagucgccc gaaacguauu cgaaugcaac gaucaggugg     1980

uuaaagguaa agaagccggu gagguacgcg uaugucucca cguacaaaaa ucgacccggg     2040

acagacuucg cgaaggacaa auccaaucag uagucaccua cgaccucgcu cuagacuccg     2100

gucgucccca uucacgagcc guguucaacg aaaccaaaaa cucuacaaga cgccaaacuc     2160

agguacucgg cuugacacaa acuugugaga ccuuaaaacu ucagcugcca aacuguaucg     2220

aggaccccgu cuccccaauc guacugcggc uuaacuucuc ucucgucggc acaccccuuu     2280

ccgcguucgg uaaccugaga cccguccucg cagaagacgc ccaacgacuc uucaccgcac     2340

ucuuccccuu ugagaaaaac ugcggcaacg acaacaucug ccaagaugac uuaagcauua     2400

cauucucauu uaugagccua gacugucucg uaguaggcgg accccgggaa uuuaacguca     2460

cuguaaccgu gcgcaacgac ggugaagacu ccuacaggac gcaagucaca uucuucuucc     2520

cccucgacuu aagcuaccgu aaagucagca cccuucagaa ccagcguucu caacgauccu     2580

ggaggcuugc gugcgaauca gcuagcucaa ccgaggucuc cggcgcgcuc aaauccaccu     2640

caugcuccau caaccacccc aucuuccccg aaaacagcga aguuaccuuc aacauaaccu     2700

ucgacguaga cuccaaggca ucacuaggaa acaaacuccu ccucaaggcc aacguaaccu     2760

ccgagaauaa caugccacgc acgaauaaaa cagaguucca auuggaacuc cccguaaaau     2820

acgcgguaua cauggucguc acuucucacg gaguaucuac caaauaccua aacuuuacag     2880

ccuccgaaaa cacaagccga guaaugcagc aucaauacca agugucaaac cugggacaaa     2940

gaucgcuacc uaucucacuc gucuuccugg uaccggucag gcuuaaccaa acggucauau     3000

gggaccgccc ccaaguaacc uuuucagaaa accucuccag cacaugccac accaaagaaa     3060

ggcucccauc acauagcgac uuccuagcag agcuccgcaa ggcgcccguc guuaacugcu     3120

ccauagcagu gugccaacgc auccagugcg acauaccauu cuuuggcauc caggaggagu     3180

ucaacgcaac ccucaaggga aaccucucuu ucgacuggua cauaaaaacu ucccacaauc     3240

accuccuaau cgucuccacc gcagaaaucc ucuucaacga cagcguauuc acccuacuac     3300

caggccaggg agcguucguc cggagccaaa ccgaaaccaa aguggaacca uuugaaguac     3360

ccaaccccuu accccuaauc gucggguccu cagucggcgg ccuacuacuu cucgcuuuaa     3420

ucaccgccgc ccucuacaaa cuaggcuuuu ucaaaagaca auacaaagac augauguccg     3480

aaggaggccc acccggggcc gaaccgcaau aaggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  3501
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt9)

<400>  3501
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguuca       60

gccucaaaac gcuccccuuc cuccuacucc uccacgucca aauaucuaaa gccuuucccg      120

ucuccucuaa agaaaagaac acaaaaacag uacaagacua ccuggaaaaa uucuaccaac      180

ucccauccaa ccaauaccag ucaacccgca aaaacggcac caacguaauc gucgaaaaac      240

ucaaagaaau gcaacgcuuc uucggacuca acgucacugg uaaaccaaac gaagaaaccc      300

ucgacaugau gaaaaagccg agaugcggcg uaccagacuc cggcggcuuu augcucaccc      360

ccggaaaccc gaaaugggaa cgcaccaacc ucaccuaccg cauacgaaac uacacacccc      420

aacucucuga agccgaaguc gaacgugcca ucaaagacgc cuucgaacuc uggucaguag      480

ccuccccacu cauuuucaca cgaaucuccc aaggugaagc cgacaucaac aucgccuucu      540

accaacgaga ccacggcgac aauucccccu uugacggccc aaacggaaua cuagcccacg      600

ccuuccaacc cggucaaggc aucggcggcg acgcccacuu cgacgcagaa gaaaccugga      660

ccaauaccuc cgcaaacuac aaccucuucc ucgucgcagc ccacgaauuu ggacacucac      720

ucggccucgc acacucuagc gaccccggcg cccucaugua ccccaacuac gccuuccgag      780

aaaccuccaa cuacucacuc ccgcaagacg acaucgaugg aauccaagcc aucuacggcc      840

ucuccuccaa cccaauccaa cccacuggcc ccucaacccc caaacccugu gacccauccc      900

ucacauucga cgccauuacc acccuccgcg gggaaauccu cuucuucaaa gaucgcuacu      960

ucuggcgccg acacccccaa cuacaacgcg ucgaaaugaa uuucaucucc cucuucuggc     1020

ccucccuccc uaccggcauu caagccgccu acgaagacuu cgaucgcgac cuuauuuuuc     1080

ucuuuaaagg caaccaauac ugggcccucu cgggcuacga cauccuacaa ggauacccca     1140

aagacaucuc caacuacgga uuccccucuu ccguccaagc uauagacgcc gccgucuucu     1200

accgauccaa gacauacuuc uucgucaaug accaauucug gcgauacgac aaccaacgac     1260

aguucaugga acccggguac cccaaaucca uuuccggagc cuucccaggc aucgaaucca     1320

aagucgacgc cgucuuccag caagaacacu ucuuccacgu cuucucaggc ccccgcuacu     1380

acgccuucga ccuaaucgcc caacgcguca cccgcgucgc ccgaggcaac aaauggcuca     1440

acugcagaua cggauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  3502
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt9)

<400>  3502
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

uguggcaacc ccucguccuc guccuucuug uccucgguug cuguuucgcc gcaccccgcc      120

aacgacaguc cacccucguc cucuuccccg gagaccuccg cacaaaccua acugaccgcc      180

agcucgccga agaauaucuu uaccgcuacg gcuacacccg cgucgcagaa augagaggcg      240

aauccaaauc ucuggggccc gcccuccucc uccuccaaaa acagcucucc cuccccgaga      300

ccggagaacu ugacuccgcc acccucaaag caaugcgaac accacgcugc ggcgucccag      360

accucggccg cuuccaaacg uucgaaggcg accuaaaaug gcaucaucac aacauuaccu      420

acuggaucca aaacuacucc gaagaccucc cccgcgccgu aauagacgac gccuucgcca      480

gagccuucgc gcucuggucc gccgucaccc cacuaacauu cacccgcguc uacucacgcg      540

acgccgacau agugauucaa uucggugucg cugaacacgg ggacggcuac cccuucgacg      600

gaaaagacgg ccuacuggcc cacgcauucc cacccggacc cggaauccaa ggugacgccc      660

acuuugacga cgacgagcuu uggucccuag gaaagggcgu cguaguccca acacgcuucg      720

gaaacgcaga cggcgccgcu ugccacuucc ccuucauauu cgaaggaagg uccuacucag      780

caugcaccac cgacggccga ucagacggcc ucccguggug cucgaccaca gcgaacuacg      840

acacagauga ccgcuucggc uucugccccu cagaacgacu auacacccag gacggcaacg      900

ccgacggaaa acccugccaa uucccauuca uauuccaggg ucagagcuac uccgccugua      960

cgacggacgg cagaagcgau ggcuaccgcu ggugcgcaac cacagcgaac uacgaccgag     1020

acaaacuuuu cgguuucugu ccaacccgcg cagacuccac cguaaugggc ggcaacagcg     1080

ccggagaacu augcgucuuc ccauucaccu uccucggaaa agaauacucc acuuguaccu     1140

cggaaggcag aggcgacgga agacucuggu gugcuacaac cucaaacuuc gacuccgaca     1200

agaaaugggg cuucugcccc gaucaaggcu acagucuauu ccucgucgca gcccacgagu     1260

ucggacacgc ccucgggcuc gaccacuccu ccguacccga agcgcuaaug uacccaaugu     1320

acagguuuac cgaaggacca ccccuacaca aagacgacgu caacggaauc cgccaccuuu     1380

acggcccccg ccccgaaccc gaaccucguc cacccaccac aacaacaccc caacccaccg     1440

caccgccaac cguauguccc acggggcccc cuaccgucca cccgagcgaa agacccacag     1500

caggcccuac cgguccaccc ucagcaggac ccacaggacc cccuacugcc ggccccucua     1560

cagccacuac ugucccccua agcccaguug acgacgcaug caacguaaac auauuugacg     1620

caaucgccga aaucggcaac caacuuuacc uauucaaaga cgguaaauac uggcgauucu     1680

ccgaaggacg cggaagucgc ccccagggcc cauuccuaau cgcagacaaa uggccagccc     1740

uaccgagaaa acuagauuca gucuucgaag aaagacuaag caagaaacuc uucuucuuuu     1800

cuggccgaca aguaugggua uacacaggag ccagcguacu aggccccaga agacucgaca     1860

aacuaggccu aggagcagac guugcacaag uaaccggagc ucuccguucc ggcagaggca     1920

aaaugcuauu guucucuggc cgcagacuuu ggcgcuucga cgucaaagcu caaaugguag     1980

acccccgauc cgcauccgag gucgaccgca uguuccccgg cguccccuua gacacacacg     2040

acguuuucca guaccgagag aaagccuacu ucugccaaga ccgcuucuac uggagaguaa     2100

gcagcagguc cgaacucaac caaguagacc aagucggaua cguaacauac gacauccucc     2160

aaugcccaga agacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  3503
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt9)

<400>  3503
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ccggaguccu cgccgcauuc cuauuccucu ccuggaccca cugccgagcc cuaccccucc      120

cauccggcgg agacgaagau gaccucuccg aagaagaccu ccaauucgca gaacgcuacc      180

uucgcuccua cuaccaccca accaaucucg caggcauccu aaaagaaaac gccgcauccu      240

caaugaccga acgccuccga gaaaugcaau ccuucuucgg ccucgaaguc accggcaaac      300

ucgacgacaa cacccucgac guaaugaaaa aaccuagaug cggaguccca gacgucggag      360

aauacaacgu auucccccgu acccugaaau ggucaaaaau gaaccucacg uacaggaucg      420

uaaacuacac ccccgacaug acccauagcg aagucgaaaa agccuucaaa aaagccuuca      480

aagucugguc cgacgucacu ccacuaaacu ucacccgucu ccacgacggc auagccgaca      540

ucaugauauc cuucggaauc aaagagcacg gcgacuucua ccccuucgac ggacccagcg      600

gucuccucgc acacgccuuc cccccgggcc ccaacuacgg cggagacgcc cacuucgaug      660

acgacgagac cuggacaucc uccucaaagg gcuacaaccu cuuccucguc gccgcccacg      720

aauucgggca cucacuugga cucgaccauu ccaaagaccc cggagcccuc auguucccaa      780

ucuacacaua caccggcaaa agucacuuca ugcuccccga cgacgacguc caaggaauuc      840

aaagccucua cggccccggc gaugaagacc ccaaccccaa acaucccaaa acacccgaca      900

agugcgaccc uucccucagc cucgacgcaa ucaccucacu cagaggcgaa accaugauau      960

ucaaagaccg auucuucugg cgacuccacc cgcaacaagu agacgccgaa cuauuccuaa     1020

ccaaauccuu cuggccagaa cuaccuaacc gaaucgacgc cgccuacgaa caccccagcc     1080

acgaccucau cuucaucuuc cgcggcagaa aauucugggc ccucaacggc uacgacaucc     1140

ucgaaggcua ccccaaaaaa auaucugaac ucggccuccc aaaagaaguc aaaaaaauau     1200

ccgccgccgu ccacuucgaa gacaccggca aaacccuacu cuuuagcggc aaccaagucu     1260

ggcgauacga cgacacgaac cacaucaugg acaaagacua cccucgccuc aucgaagaag     1320

acuucccagg aaucggcgau aaaguagacg cgguuuacga aaaaaacggc uacaucuacu     1380

ucuucaacgg cccaauacaa uucgaauacu ccauaugguc caaccgaaua gucagaguga     1440

ugccagcaaa uucaauccuc uggugcuaag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3504
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt9)

<400>  3504
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

cccccaacac aaccgaagac uacgacacca ccacggaguu cgacuacggc gacgccaccc      120

ccugccaaaa gguaaacgaa cgagccuucg gcgcacaacu ucucccaccc cuguacuccc      180

uaguguucgu aauaggccuc gucggcaaua uccuagucgu auuaguccuc guccaauaca      240

aacgccucaa gaacaugacc ucuauauacc uacucaaccu agcaaucucc gaccuccuuu      300

uccuguucac ccuccccuuc uggaucgacu auaaacucaa agacgauugg gucuucggag      360

acgccaugug caaaauccuc uccggcuucu auuauaccgg ucucuacucc gaaaucuucu      420

ucauaauccu ccucaccauc gacagauauc ucgccauagu ccacgccguc uuugcacucc      480

gcgcccgcac cgucaccuuc ggugucauca ccuccaucau aaucugggcc uuagccaucc      540

ucgccuccau gcccggacuc uacuuuucca aaacccaaug ggaguucacc caccauaccu      600

gcucccucca cuucccccac gaaucccuac gcgaauggaa acucuuccaa gcacuaaaac      660

uaaaccucuu uggccucguc cuuccccucc uagucaugau caucugcuac acaggcauca      720

ucaaaauccu acuucgucgc ccuaaugaaa agaaauccaa agccguccga cucaucuucg      780

ucaucaugau aaucuuuuuc cucuucugga cacccuauaa ucucaccauc cucaucucug      840

ucuuccaaga cuuccucuuc acacacgaau gcgaacaauc ccgccaccua gaccucgccg      900

uccaagucac cgaagucauc gcauacaccc acugcugcgu caaccccguc auauacgcau      960

ucgucggcga acgcuuccgc aaguaccucc gccaacucuu ccaccgacgc gucgcagucc     1020

aucucgucaa augguuaccc uuucucucug ucgaccgccu cgaacgcgua uccucaacau     1080

cacccuccac cggcgaacau gaacuuucag ccggcuucua aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  3505
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt9)

<400>  3505
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcgaa       60

cccucgccug ccuccuccuc cucggcugcg gcuaccucgc ccacguacuc gccgaagaag      120

cagaaauccc ccgcgaaguc aucgaacgcc ucgcacgcuc ccaaauccac uccauccgug      180

accuccaacg acuccuggaa aucgacuccg ucggauccga agacucccua gacaccuccc      240

uaagagccca cggcguacac gccacaaaac acguccccga aaaacgaccc cuccccaucc      300

gcagaaaacg auccauagaa gaagccgucc ccgccguaug caaaacacgc acagucaucu      360

acgaaauacc ccgcucccaa gucgacccaa ccuccgccaa cuuccuaauc uggccccccu      420

gcgucgaagu caaacgcugc accggcugcu gcaacaccuc cucagucaaa ugccaaccca      480

gccgcgucca ccaccgcagc gucaaagucg caaaagucga auacguacgc aaaaaaccca      540

aacucaaaga aguccaaguc agacucgaag aacaccuaga augcgcaugc gccaccacca      600

gccuaaaccc agacuaccgc gaagaagaca ccggccgacc ccgcgaaucc ggcaaaaaac      660

gcaaacgcaa aagacuaaaa cccaccuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  3506
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt9)

<400>  3506
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacc       60

gcugcugggc ccuauuccua agccuaugcu gcuaccuccg ccuagucucg gccgagggcg      120

accccauccc cgaagaacuc uacgaaaugc ucagcgauca cucaauccgc uccuucgacg      180

accuccaacg ccuccuccac ggcgaccccg gcgaagaaga cggagccgaa cuagaccuca      240

acaugacacg cucacacucc ggaggggaac ucgaaucccu cgcacgcggc cgccgcagcc      300

uaggcucacu aacaaucgcc gaaccagcaa ugaucgccga augcaaaaca agaacagaag      360

ucuucgaaau cucacgccgc cuaaucgacc gcaccaacgc caacuuccua gucuggccac      420

ccugcgucga aguccaaaga ugcuccggau gcugcaacaa cagaaacguc caaugccgcc      480

ccacccaagu ccaacuccga ccaguacaag uaagaaaaau agaaaucguc cgcaaaaaac      540

ccaucuucaa aaaagcaacc guaacccucg aagaccaccu cgcaugcaaa ugcgaaaccg      600

ucgccgcagc ccgccccguc acccgcagcc ccggcggaag ccaagaacaa cgagcaaaaa      660

caccccaaac cagagucacc auccgaacag uccgcguacg cagacccccc aaaggaaaac      720

accgcaaauu caaacacaca cacgacaaaa ccgcccuaaa agaaacccua ggcgccuaag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  3507
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt9)

<400>  3507
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccc       60

ucuucggccu acuccuccua acaucugcac ucgccggcca acgccaaggc acccaagccg      120

aauccaaccu cagcucuaaa uuccaauucu ccucaaacaa agaacaaaac ggcguccaag      180

acccccaaca cgaacgcaua aucacagucu caaccaacgg cuccauccau ucaccccguu      240

ucccccacac cuacccccgc aacaccgucc uaguauggcg ccuaguagca guagaggaaa      300

acgucuggau ccaacucacc uucgacgaac gcuuuggacu cgaagaucca gaagacgaua      360

ucugcaaaua cgacuucguc gaaguagaag aaccuuccga cggcacaauc cuaggccgau      420

ggugcggcuc cggcaccguc ccaggcaaac aaauauccaa aggcaaccaa auccgcaucc      480

gcuucgucuc cgacgaauac uuccccuccg aacccggcuu cugcauccac uacaacaucg      540

ucaugcccca auucaccgaa gccgucuccc ccuccguccu cccacccucc gcacuccccc      600

uagaccugcu caacaacgcc aucaccgccu ucucaacccu cgaggaccuc auacgcuacc      660

uagagcccga acgcuggcaa cucgaccucg aagaccucua ccgcccaaca uggcaacucc      720

ucggcaaagc cuucgucuuc ggccgcaaau cccgcguagu cgaccuaaac cuacuaaccg      780

aagaaguacg ccucuacagc ugcacaccac gcaacuucuc agucuccauc cgcgaagaac      840

ucaaacgcac cgacaccauc uucuggccag gcugccuccu aguaaaacgc ugcggcggga      900

acugcgccug cugccuccac aacugcaacg aaugccaaug cgucccaucc aaagucacca      960

agaaauacca cgaagugcua caacuaagac caaaaaccgg cguccgcgga cuccacaaau     1020

cucucaccga cguagcccua gaacaccacg aagaaugcga cugcgucugc cgcggcucca     1080

ccggcggcua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  3508
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt9)

<400>  3508
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

gccucauauu ugucuacaca cugauaugcg ccaacuucug uucaugccgc gacaccuccg      120

ccacccccca aucugccucc auaaaagccc ucagaaacgc caaccuacga cgcgacgacc      180

ucuaccgacg cgacgaaaca auacaaguca aaggcaacgg cuacguacaa uccccacgcu      240

uccccaacuc cuacccccgc aaccuccucc ucaccuggcg gcuacacucc caagaaaaca      300

cccgcauaca gcuuguauuc gacaaccaau ucggccuaga agaagccgag aacgacaucu      360

gccgauacga cuucgucgaa gucgaagaca ucagcgaaac cuccaccauc aucagaggaa      420

gauggugcgg ccacaaagaa guccccccuc gaaucaaauc ccgcacaaac cagauaaaaa      480

uaacauucaa auccgacgac uacuucgucg ccaaacccgg cuucaaaauc uacuacuccc      540

uccucgaaga uuuccaaccc gccgccgccu ccgaaacaaa cugggaaucc gucaccuccu      600

ccauauccgg ugucucauac aacuccccaa gcgucacaga cccaacccuc auugcagacg      660

cacuagacaa aaaaaucgcc gaauucgaca ccgucgagga ccuccuaaaa uacuucaacc      720

ccgaauccug gcaagaagac cucgaaaaca uguaccucga cacaccccgc uacagaggcc      780

gcuccuacca cgaccgcaaa uccaaggucg accucgaccg ccucaacgac gacgccaaac      840

gcuacagcug cacaccccgc aauuacagug ucaacaucag agaggaacua aaacuagcca      900

acguagucuu cuucccacgc ugccuacuag uacagcgaug cggcggcaac ugcggcugcg      960

gcaccgugaa cuggcggucc ugcaccugua acuccggcaa aacaguaaaa aaauaucacg     1020

aaguccuaca guuugaaccc ggacacauca aacgccgugg ccgcgccaaa acuauggccc     1080

ucguugacau ccaacucgac caccacgaac gcugcgacug cauaugcucu ucccgcccac     1140

cccgauaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  3509
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt9)

<400>  3509
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguca       60

cccauucaaa auuccccgcc gccggcaugu cccgcccccu cgacaccucc cuccgccuca      120

aaacauucuc cuccaaaucc gaauaccaac ucgucgucaa cgccguccgc aaacuccaag      180

aauccggcuu cuacuggucu gccgucaccg gaggcgaagc caaccuccua cuaucagccg      240

aaccagcugg caccuuccua auccgugacu ccuccgacca acgccacuuc uucacccucu      300

cagucaaaac ccaauccggc accaaaaacc uccgcaucca augcgaaggc ggauccuucu      360

cccuacaauc cgacccccgc ucaacucaac cagucccccg auucgacugc guccucaaac      420

ucguccacca cuacaugccc ccacccggag cccccuccuu ccccucccca cccaccgaac      480

ccuccuccga aguccccgaa caacccuccg cccaaccccu ccccggauca ccaccccgcc      540

gcgccuacua caucuacucc ggcggcgaga aaaucccccu aguccucucc cgcccacucu      600

cauccaaugu ugccacccua caacaccucu gccguaaaac cguaaacgga caccuagacu      660

ccuacgaaaa aguuacccaa cuacccggcc ccauccgcga auuucucgac caauacgaug      720

caccccucua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  3510
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt9)

<400>  3510
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucc       60

ccuccgccgg ccaacuagcc cucuucgccc uaggcaucgu ccucgcagcc ugucaagcac      120

ucgaaaacuc caccuccccc cucucagccg acccacccgu agccgcagcc guagucuccc      180

acuucaacga cugccccgac ucccacaccc aauucugcuu ccacggaacc ugccgauucc      240

ucguccaaga agacaaaccc gccugcguau gccacuccgg cuacgucggc gcccgcugcg      300

aacacgccga ccuccuagcc guaguagccg ccucacaaaa aaaacaagcc auaaccgcac      360

ucguagucgu cuccaucguc gcccucgccg uccuuauaau aaccugcguc cucauccacu      420

gcugccaagu acgcaaacac ugcgaauggu gccgcgcccu caucugcaga cacgaaaaac      480

ccuccgcacu acucaaaggc cgcaccgccu gcugccauuc cgaaaccgua guauaaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  3511
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt9)

<400>  3511
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

cauccggccu acgucuccuc ccucuccucc ugccacuccu cuggcuauua guccuaacac      120

caggccgccc agccgccggc cucucaaccu gcaaaacuau cgacauggaa cuugucaaac      180

gcaaacgaau agaagccauc cgcggccaaa uccuauccaa acuccgccuc gccuccccac      240

ccucacaagg cgaaguacca cccggacccc uacccgaagc cguccuugca cucuauaacu      300

ccacccgcga ccgaguugcu ggagaaucag ccgaacccga accagagcca gaagccgacu      360

acuacgccaa agaagucacc cgcguacuca uggucgaaac acacaacgag auauacgaua      420

aauucaagca auccacccac uccauauaca uguucuucaa caccucagaa cuacgagaag      480

ccguccccga acccguccua cuaucacgag ccgaacuucg ucuccuccga cucaaacuca      540

aggucgaaca acacgucgaa cucuaccaaa aauauucaaa caacucaugg cgcuaccuau      600

caaaccgccu acuagcacca ucagacucac ccgaauggcu aucauucgac gucaccggag      660

ucguccgcca auggcuauca cgaggaggcg aaaucgaagg cuucagacuc ucagcccacu      720

gcuccugcga cucccgagac aacacccucc aagucgacau caacggcuuc accaccggcc      780

gacgcggaga ccucgccaca auacacggaa ugaaccgacc cuuccuacuc cucauggcaa      840

caccacucga acgcgcccaa caccuccaau cuucccgcca ccgccgagcc cuggacacca      900

acuacugcuu cuccuccacu gagaaaaauu gcugcgugag acaacucuac aucgacuucc      960

gcaaagaccu cggcuggaaa uggauccacg aaccaaaagg cuaccacgca aacuucugcc     1020

ucggccccug cccauacaua uggucccuag acacccaaua cuccaaaguu cuagcccuau     1080

acaaccaaca caaccccggc gccuccgcgg cucccugcug cguuccccaa gcccucgaac     1140

cccucccaau agucuacuac gucggccgca aaccaaaagu cgaacaacuc uccaacauga     1200

ucguccgauc cugcaaaugc uccuaaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  3512
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt9)

<400>  3512
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugcguacu cucagccuuc cucauccucc accucgucac cgucgcacua ucacuaucua      120

ccugcagcac acucgauaug gaccaauuca ugcgcaaacg cauagaagcu auccguggcc      180

aaauccuauc caaacucaag cucaccagcc cacccgaaga cuauccugaa cccgaagaag      240

ucccacccga aguaaucucc aucuacaacu ccacacgcga ccuccuacaa gaaaaagccu      300

cccgacgcgc agccgccugc gaacgagagc gcuccgacga agaauacuac gccaaagaag      360

uauacaagau agacaugcca cccuucuucc cuuccgaaaa cgccauaccc ccaaccuucu      420

accgcccaua cuuccgcauc guccgcuucg acgucucugc uauggagaaa aaugcaucca      480

accucgucaa agccgaguuc cgcguauucc gccuacaaaa ccccaaagcg cgcgucccug      540

aacaacgcau cgaacucuac cagauccuca aauccaaaga ucuuaccucg cccacacaac      600

gcuacaucga cuccaaaguc guaaagaccc gcgccgaagg agaauggcuc uccuucgacg      660

uaaccgacgc cguccacgaa uggcuacacc acaaagaccg caaccucggc uucaaaaucu      720

cccuacacug ccccugcugc accuucgucc ccuccaacaa uuacaucauc cccaauaaau      780

ccgaagaacu cgaagccaga uucgccggca ucgacggcac cucaaccuac acauccggcg      840

accagaaaac caucaaauca acccgcaaga aaaacuccgg caaaacccca caucuccucc      900

ucaugcuucu cccuucauac cgucucgaau cucaacaaac caaccgacgc aagaaacgcg      960

cccucgacgc cgccuacugu uuccgcaacg uccaagacaa cugcugccua cgaccccucu     1020

acauagacuu caaacgcgac cucggcugga aauggaucca cgaacccaaa ggcuacaacg     1080

cuaacuucug cgcgggcgcc ugccccuacc uaugguccuc cgacacccaa cacucacgcg     1140

uccucucccu cuacaacacc aucaauccug aagccuccgc cucacccugc ugcgucuccc     1200

aagaccucga accacucacc auacuauacu acaucggcaa aacgccuaaa auagaacaac     1260

uaucuaacau gaucgucaaa uccuguaaau gcagcuaagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  3513
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt9)

<400>  3513
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

ugcaccucca acgcgcccua gucguacucg cacuacucaa cuuugccacc guaucacuuu      120

cacucuccac augcaccaca cucgacuuug gccacaucaa aaagaaacga gucgaagcua      180

uacgaggcca aauccuauca aaacuacgcc ucacaucccc acccgaaccc acaguaauga      240

cccacguccc cuaccaagua cucgcccuau acaacuccac ccgcgaacuc cuagaagaaa      300

ugcacggaga aagagaagaa ggaugcaccc aggaaaacac cgaaucagaa uacuacgcca      360

aagaaauaca caaauucgac augauccaag gccucgccga acacaacgaa uuagccgucu      420

gccccaaagg uaucacuagc aaaguauucc gauucaacgu uuccucgguc gagaaaaacc      480

gcaccaaccu auuccgagcc gaguuccgug uccuccgcgu ccccaaccca agcucaaaac      540

gcaacgaaca acgcaucgaa cuuuuccaaa uacuaagacc cgacgaacac aucgccaaac      600

aacgcuacau aggcggcaaa aaccucccaa cccgcggcac cgcagaaugg cucucuuucg      660

acgucaccga caccguacgu gaauggcuac ucagacgcga auccaaccua ggucuagaaa      720

ucucaauaca cugccccugc cacaccuucc aaccaaacgg agacauccuc gaaaacaucc      780

acgaagucau ggaaaucaaa uucaaaggag ucgacaauga agacgaccac ggacgaggcg      840

accucggacg acucaaaaag caaaaagacc accacaaccc ccaccucauc cuaaugauga      900

ucccacccca ccgccucgac aaccccggac aaggcggcca acgcaagaaa cgcgcccucg      960

acaccaacua cugcuuccgc aaccuagaag aaaacugcug cguacgcccc cucuacaucg     1020

acuuccgaca agaccuaggc uggaaauggg uccacgaacc caaaggauac uacgcaaauu     1080

ucugcagcgg accaugccca uaccuacggu ccgccgacac aacccacucc acaguccuag     1140

gacuuuauaa cacccuaaac ccagaagccu ccgccucccc cugcuguguc ccccaagacc     1200

uugaaccucu caccauccuu uacuacgucg gcagaacccc caaagucgaa caacuaucca     1260

acauggucgu caaauccugc aaaugcuccu aaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3514
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt9)

<400>  3514
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

ccguugcagu cugggcagcc cuugccgucg gccucgaacu cugggccgcu gcccacgccc      120

uccccgccca aguugccuuc acuccuuacg ccccagaacc aggcuccaca ugccgacucc      180

gagaauacua ugaccaaaca gcccaaaugu gcugcuccaa gugcuccccc ggccaacacg      240

ccaaagucuu cuguaccaaa accucugaca ccgucugcga cuccugcgaa gacuccacuu      300

acacccaacu auggaacugg guacccgaau gccucuccug cggcuccaga ugcucauccg      360

accaagucga aacccaagca ugcacacgcg aacaaaaccg aaucugcaca ugcaggcccg      420

gaugguacug cgcacucucc aaacaagaag gcugccgccu cugcgcaccc cuccgaaaau      480

gccgaccagg cuucggcguc gcccgcccag gaacagaaac cuccgacgua gucugcaaac      540

ccugcgcccc uggcacuuuc uccaacacaa ccagcucaac cgacauaugc cgcccacacc      600

aaaucugcaa cgucguugca auacccggca acgcauccau ggacgccguc ugcaccucca      660

caucgcccac ccgauccaug gcacccggcg ccguccaccu cccccaaccu gucucaaccc      720

gaucacaaca cacacaaccc acccccgaac ccucaaccgc cccauccacc ucauuccuuc      780

uacccauggg ccccucccca cccgccgaag gcuccaccgg agacuucgcc cucccagucg      840

gccuaaucgu cggcgucacc gcccuaggcc ugcucaucau cggagucguc aacugcguaa      900

ucaugaccca agucaaaaag aagccccuau gucuccaaag agaagcaaaa guaccucacc      960

uccccgccga caaagcccgc ggcacacaag gccccgaaca acaacaccuc cuaaucaccg     1020

ccccaucauc cuccucauca agccucgaau caucagcauc agcucucgac cgccgcgccc     1080

caaccagaaa ccaaccccag gccccaggcg uagaagccuc cggagccgga gaagcccgag     1140

ccucaacagg cuccuccgac agcucucccg gcggccacgg cacacaagua aacguaaccu     1200

gcaucgucaa uguaugcucg ucauccgacc auuccuccca augcucaagc caagccucau     1260

caaccauggg cgacaccgac ucaagcccau cugaaucccc caaagacgaa caaguacccu     1320

ucaguaaaga agaaugugcc uuccgauccc aauuagaaac ccccgaaaca cuccuaggau     1380

ccaccgaaga aaaacccuua ccccucggug ucccagacgc cggcaugaaa cccuccuaag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  3515
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt9)

<400>  3515
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgg       60

ucaugcgcuu guucccgugc uuucuacagc ucuuggcagg gcucgcacuc ccagccgugc      120

ccccgcaaca gugggcguua ucggccggga acgggagcuc ggaaguggaa gugguaccgu      180

uccaggaagu gugggggcgc ucguacuguc gcgcgcuaga gcgccugguc gaugucguga      240

gugaguaccc gagcgagguc gagcacaugu ucucgcccuc augcgugagc uugcucaggu      300

gcacgggcug uugcggggac gagaaccugc acuguguccc ggucgagacc gcgaacguga      360

ccaugcaauu gcucaagauc aggagcgggg acaggcccuc guacguggaa uugaccuuca      420

gccagcacgu acgcugugaa ugucgcccac ucagggaaaa gaugaagcca gaacgcaggc      480

gaccgaaagg gcgcgggaaa aggcgcagag aaaagcaaag gcccacagac ugucacuuau      540

gcggggacgc ggucccgagg cgcugaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  3516
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt9)

<400>  3516
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugacag       60

accgccagac agacaccgcg ccaucgcccu cguaccaccu ccugcccggg agaaggcgca      120

cggucgacgc cgcagccucg cgaggacaag ggcccgagcc agcgccagga ggcgggguag      180

agggcguggg agcgcgaggg gucgcgcuca aacucuucgu ccagcuucug ggcugcagca      240

gguucggggg cgcaguagug cgcgcaggcg aagccgagcc cucaggcgcg gccaggagcg      300

caagcucagg cagagaggaa ccccagcccg aggaggggga agaagaagag gaaaaagaag      360

aagaaagggg uccacaaugg cgccugggcg cgcgcaagcc aggaaguugg accggagaag      420

cagcagugug cgcggacucu gcaccagccg cgcgagcgcc ccaggcauug gccagagcau      480

caggcagagg aggacgagug gcaagaagag gagccgagga aucaggaccg ccccauagcc      540

caagcaggcg agggagugcg agcagagccg gaccagggcg cgcaagcgag acaaugaacu      600

uccuccugag cuggguacac uggucgcuag cacuguugcu cuaccuccau cacgcaaaau      660

ggagccaggc cgcgccaaug gccgagggag gaggacaaaa ccaccacgag guagugaaau      720

ucauggacgu cuaccaaagg agcuauugcc accccauaga aacgcuagug gacauauucc      780

aggaauaucc agacgaaaua gaguacauau ucaaaccaag cugcgugccg cucaugaggu      840

gcggcggaug cuguaacgau gaagggcuag agugcguacc cacggaagag agcaacauca      900

ccaugcagau caugaggaua aaaccgcacc agggccagca cauaggagag augucauucc      960

ugcaacacaa caagugcgag ugccggccca agaaagaccg agcaagacag gaaaagaaau     1020

caguaagggg aaagggcaag ggacagaaaa gaaaaagaaa gaagaguagg uacaagagcu     1080

ggaguguaua cguaggggcg agaugcugcc ugaugccaug gagccuaccg ggaccgcacc     1140

caugcggacc cugcagcgaa cgcaggaaac accuguucgu ccaggaccca caaacaugca     1200

aguguucaug caagaacaca gacucgcgcu guaaagcacg ccaacucgag cuuaacgaaa     1260

ggacaugccg cugcgacaaa cccaggagau aaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3517
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt9)

<400>  3517
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuacucag cuggguccac uggucacucg cccuccuccu cuaccuccac cacgccaaau      120

ggucccaagc cgcccccaug gccgaaggcg gcggccaaaa ccaccacgaa guaguaaaau      180

ucauggacgu auaccaacgc agcuacugcc accccaucga aacccuagua gacaucuucc      240

aagaauaccc cgacgaaauc gaauacauau ucaaacccuc cugcguccca cucaugcgcu      300

gcggcggcug cugcaacgac gaaggccucg aaugcguccc cacagaagaa agcaacauca      360

caaugcagau aaugcgaauc aaaccccacc aaggccagca caucggcgaa augucauucc      420

uccaacacaa caaaugcgaa ugccgaccaa aaaaagaccg cgcaagacaa gaaaaaaaau      480

ccgucagagg caaaggcaaa ggccaaaaac gaaaacgcaa aaaaucccgc uacaaaagcu      540

ggucagucua cguaggcgcc cgcugcugcc ucaugccaug gucccucccc ggcccccacc      600

ccugcgggcc cugcagcgaa cgccgcaaac accucuucgu ccaagaccca caaaccugca      660

aaugcuccug caaaaacacc gacucccgcu gcaaagcccg ccaacucgaa cuaaacgaac      720

gcaccugccg cugcgacaaa ccccgaagau aaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  3518
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt9)

<400>  3518
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccc       60

cccuccuccg ccgacuccua cuagccgccc uccuacaacu cgcccccgca caagcccccg      120

ucucccaacc cgacgccccc ggccaccaac gcaaagucgu auccuggaua gacguauaca      180

cccgcgccac cugccaacca cgagaagucg uagucccacu cacagucgaa cucaugggca      240

ccgucgcaaa acaacucgua ccaucaugcg uaaccgucca acgaugcggc ggcugcugcc      300

ccgacgacgg ccuagaaugc guccccaccg gccaacacca agucagaaug caaauccuca      360

ugauccgcua ccccuccucc caacucggcg aaaugucacu cgaagaacac ucccaaugcg      420

aaugccgccc caaaaaaaaa gacucagccg uaaaacccga ccgcgccgcc acaccacacc      480

accgacccca accccgcuca gucccaggcu gggacuccgc ccccggcgca cccucccccg      540

ccgacaucac ccaccccacc cccgcacccg gccccuccgc acacgccgcc ccauccacca      600

ccuccgcccu cacccccggc cccgccgccg ccgccgccga cgccgccgcc agcuccgucg      660

caaaaggcgg cgccuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  3519
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt9)

<400>  3519
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

uccucggauu cuucuccguc gccugcuccc uacucgccgc cgcacuccuc cccggcccac      120

gcgaagcacc agcagccgcc gccgcauucg aaucaggccu cgaccuaucc gacgccgaac      180

cagacgccgg cgaagccacc gccuaugcaa gcaaagaccu cgaagaacaa cuacgauccg      240

uaucauccgu ggacgaacua augaccgucc ucuacccaga auacuggaaa auguacaaau      300

gccaacuccg aaaaggcgga uggcaacaua accgcgaaca agccaaccuc aacagccgaa      360

ccgaagaaac aaucaaauuc gccgccgccc acuacaacac ggaaauacua aaauccaucg      420

acaacgaaug gagaaaaaca caaugcaugc cccgugaagu cugcaucgac gucggcaaag      480

aauuuggcgu cgccaccaac acauucuuca aaccacccug cgucucagua uaccgaugcg      540

gcgggugcug caacuccgaa ggccuacaau gcaugaacac cuccaccuca uaccucucaa      600

aaacccucuu cgaaauaaca guuccacuca gccaaggccc caaacccguc acgauauccu      660

ucgcaaacca uacuucaugc cgcugcaugu caaaacuuga cguauaccgc caaguccacu      720

ccaucauccg aagaucacua cccgccaccc uaccccaaug ucaagccgcc aacaaaaccu      780

gccccaccaa cuacaugugg aacaaccaca uuugccgcug ccuagcccaa gaagacuuca      840

uguucucauc ggacgccggc gacgacucaa ccgacggcuu ccacgacaua ugcggcccca      900

acaaagaacu agacgaagaa acaugccaau gcgucugccg cgccggccuc cgacccgcau      960

ccugcggacc ccacaaagaa cuggaccgca acucaugcca augcgucugc aaaaacaaac     1020

ucuuccccuc ccaaugcggc gcaaaccgcg aguucgacga aaauaccugc caaugcgucu     1080

gcaagcgaac cugcccacgc aaccaacccc ucaaccccgg aaagugcgcc ugcgaaugca     1140

ccgaaagccc acaaaaaugc cuucucaaag gaaagaaauu ccaccaccaa accugcucau     1200

gcuaccgccg ccccugcacc aaccgccaaa aagccugcga acccggcuuc ucauacuccg     1260

aagaaguaug ccgcugcguu ccaagcuacu ggaaacgccc ccaaaugucc uaaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  3520
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt9)

<400>  3520
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguacc       60

gagaaugggu agucgucaac gucuucauga ugcucuacgu ccaacugguc caagguucau      120

ccaacgaaca uggccccguc aaacgcuccu cccagagcac ccucgagcgc uccgaacaac      180

aaauccgcgc ugccuccucu cuagaagaac uucuccgaau cacccacucu gaagacugga      240

aauuauggcg augccgccua cgucucaaga gcuucaccuc aauggacucc cgauccgcau      300

cccaccgcuc uacacgauuc gccgccaccu ucuacgacau cgaaacccuc aaagucauag      360

acgaagaaug gcaacgcacc caaugcuccc caagggaaac cugcgucgaa guagccuccg      420

aacucggcaa auccaccaac acauucuuca aaccucccug cgucaacguc uuccgcugcg      480

gcggcugcug caacgaagaa ucccucaucu gcaugaacac auccaccucc uacauaucca      540

aacaacuauu cgaaauuucu gucccccuca ccucgguccc cgaacucguc cccgucaaag      600

uagccaacca caccggcugc aaaugccugc ccaccgcccc acgacacccc uauuccauca      660

uccgacgcuc cauacagauu cccgaagaag accgaugcuc ccacucaaag aaacucugcc      720

ccauagacau gcuaugggac ucaaacaaau gcaaaugcgu ccuccaagaa gaaaacccac      780

ucgccggcac ugaagaccac ucgcaccucc aagaacccgc ccucugcgga ccccacauga      840

uguucgacga agaccgcugc gaaugcgucu gcaaaacccc augccccaaa gaccucaucc      900

aacaccccaa aaacugcuca ugcuucgaau gcaaagaauc ccucgagacc ugcugccaaa      960

aacacaaacu cuuccacccc gauaccugcu ccugcgaaga ccgcugcccc uuccacacac     1020

gcccaugcgc cuccggcaaa accgcaugcg caaaacacug ccguuuccca aaagaaaaac     1080

gcgccgccca aggcccccac ucccgcaaaa accccuaagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  3521
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt11)

<400>  3521
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

ccgacgaaac cggcuucgaa cacucaggcc ucugggucuc cguacuagcc ggccuccucc      120

ucggcgccug ccaagcccac cccauccccg acuccucacc ccuccuacaa uucggcggcc      180

aaguccgcca acgcuaccua uacaccgacg acgcccaaca aaccgaagcc caccucgaaa      240

uccgcgaaga cggcaccguc ggcggcgccg ccgaccaauc ccccgaaucc cuacuacaac      300

ucaaagcccu caaaccugga gucauccaaa uacucggcgu caaaaccucc cgcuuccucu      360

gccaacgccc cgacggagcc cucuacggcu cccuccacuu cgacccagaa gccugcucuu      420

uccgagaacu ccucuuagaa gacggcuaca acgucuacca aucugaagcc cacggccucc      480

cccuucaccu ccccggaaac aaaucacccc accgcgaccc cgcaccccgc ggcccagcca      540

gauuccuccc ccuccccggc cucccaccag cccuccccga accacccggc auccucgcac      600

cccaaccacc cgacgucggc uccuccgacc cccucucaau ggucggcccc ucccaaggcc      660

gcucccccuc auacgccuca uaaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  3522
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt11)

<400>  3522
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gcuucccacc ccuccuccuc cuccuguucu ggggcgucgu cucacacucc uuucccgcua      120

cccucgaaac ccaagaacaa gacgucgacc ucguacaaaa guaccucgaa aaauacuaca      180

accuuaaaaa cgacggccgu caagucgaaa agcgccgcaa cucaggcccc gucguugaaa      240

aacucaaaca aaugcaagaa uuuuucggcc ugaaagucac aggaaaaccc gacgccgaaa      300

cccucaaagu caugaaacaa ccccgcugcg gaguccccga cguagcccaa uucguccuaa      360

ccgaaggcaa cccccgcugg gaacaaaccc accucacaua ccgcaucgaa aacuacaccc      420

ccgaccuucc ccgcgccgac gucgaccacg ccauagaaaa agcauuccaa uuauggucca      480

acgucacccc acucaccuuc acuaaggucu ccgaaggcca agcagacaua augaucucuu      540

ucguccgcgg cgaccaccga gacaacuccc ccuucgacgg ccccggaggc aaccuggccc      600

acgcauucca accaggcccc ggcaucggag gagacgccca cuucgacgaa gacgaacgcu      660

ggacaaacaa uuucagagaa uacaacuuac aucgcgucgc cgcccacgaa cucggccaca      720

gccucggccu cucacacucc acagauaucg gcgcccuaau guaccccucc uacaccuucu      780

ccggcgacgu ccaacuagcc caagacgaca uagacggcau ccaagccaua uacggccgau      840

cccaaaaccc cguacagccc aucggaccac aaacucccaa agccugcgac uccaaacuca      900

ccuucgacgc caucaccaca auacgaggcg aagugauguu cuucaaagac agauucuaua      960

ugagaaccaa cccguucuac cccgaagucg aacuuaacuu caucucaguc uucuggccac     1020

aacuaccaaa cggccucgaa gcagccuacg aauuugccga ccgcgacgaa guccgauucu     1080

ucaagggcaa caaauacugg gccguccaag gccaaaacgu ccugcacggc uacccaaaag     1140

acaucuauuc cagcuucggc uucccacgca cugucaaaca uaucgaugcc gcccucagcg     1200

aagaaaacac aggcaaaaca uacuucuucg ucgcuaacaa auacuggcgc uacgaugaau     1260

acaaacgcuc cauggaccca ggcuauccua aaaugaucgc ccacgacuuc cccggcaucg     1320

gccacaaggu cgaugccguc uucaugaagg acggauucuu cuacuucuuc cacggaaccc     1380

gccaauacaa guucgacccc aaaacuaagc gaauccucac ccuccaaaaa gccaacuccu     1440

gguucaacug ccgcaaaaac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  3523
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt11)

<400>  3523
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcauu       60

cauucccacc acuacuacuc cuccuauucu ggggagucgu cucccauucc uucguccuca      120

cagaaggcaa cccccgcugg gaacaaaccc accucaccua ccgcauagaa aacuacaccc      180

cagaccuccc ccgcgccgac gucgaccacg ccaucgaaaa agcguuccaa cuauggucua      240

acguaacacc ccucaccuuc accaaagucu ccgaaggcca agccgacaua augaucucau      300

ucgucagagg cgaccaccgc gacaacucuc ccuucgacgg ccccggaggc aaccucgcac      360

acgccuucca acccggcccc ggaaucggcg gcgacgccca cuucgacgaa gacgaacgcu      420

ggaccaacaa cuuccgagaa uacaaccucc accgcgucgc cgcacacgaa cucggccaca      480

gccucgggcu cucacacucc accgacaucg gugcccucau guaccccuca uacacauucu      540

cuggcgacgu ccaacucgca caagacgaca ucgacggcau ccaagccauc uacggccgau      600

cccaaaaccc aguccaaccc auaggcccac agacacccaa agcaugcgac uccaaacuca      660

ccuucgacgc cauaaccacc auccgcggcg aaguaauguu cuucaaagac agauucuaca      720

ugcgcaccaa ccccuucuac ccagaaguug aauuaaacuu caucuccguc uucuggccac      780

agcucccaaa cggucucgaa gccgcauacg aauuugcaga ccgagacgaa guacgauucu      840

ucaaaggcaa caaauauugg gccguacagg ggcaaaaugu ccuccacggc uacccuaaag      900

acaucuacuc cuccuucggc uucccccgca cagucaaaca caucgacgcc gcccucuccg      960

aagaaaacac cggcaaaacc uacuucuucg ucgccaacaa auacuggcga uacgacgaau     1020

acaaacgcuc cauggacccc ggauacccca aaaugaucgc ccacgacuuc cccggcaucg     1080

gccacaaagu agacgccguu uucaugaaag acggauucuu cuacuucuuc cacggaacaa     1140

gacaguacaa auucgaccca aagaccaaac ggauccucac ccuccaaaaa gcaaacuccu     1200

gguucaauug ccgcaaaaau uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  3524
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt11)

<400>  3524
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

agaacauccu gaagauccuc auggacagcu acuccaagga gagcaagauc cagaccgugc      120

gccgggucac cuccgugagc cugcuggccg uguaccucac gaugaacacc uccagccugg      180

uccuggccaa gcccaucgag aacaccaacg acaccuccau caagaacgug gagaagcucc      240

gcaacgcgcc gaacgaggag aacagcaaga agguggagga cuccaagaac gacaaggucg      300

agcacgugaa gaacaucgag gaggccaagg uggagcaggu cgcccccgag gucaagagca      360

aguccacgcu gcggagcgcc uccaucgcca acaccaacag cgagaaguac gacuucgagu      420

accugaacgg ccucuccuac accgagcuga ccaaccugau caagaacauc aaguggaacc      480

agaucaacgg ccucuucaac uacagcacgg ggucccagaa guucuucggg gacaagaacc      540

gcgugcaggc gaucaucaac gcccugcagg agagcggccg gaccuacacc gccaacgaca      600

ugaaggggau cgagaccuuc acggaggugc ugcgcgccgg cuucuaccuc ggcuacuaca      660

acgacgggcu guccuaccug aacgaccgga acuuccagga caagugcauc cccgcgauga      720

ucgccaucca gaagaacccc aacuucaagc ucggcaccgc cgugcaggac gaggugauca      780

ccagccuggg gaagcugauc ggcaacgcca gcgccaacgc ggaggucgug aacaacugcg      840

ugccgguccu caagcaguuc cgcgagaacc ugaaccagua cgcccccgac uacgugaagg      900

ggaccgccgu gaacgagcug aucaagggca ucgaguucga cuucuccggc gccgccuacg      960

agaaggacgu caagacgaug cccugguacg ggaagaucga ccccuucauc aacgagcuca     1020

aggcgcuggg ccuguacggg aacaucacca gcgccaccga gugggccucc gacgugggca     1080

ucuacuaccu cagcaaguuc ggccuguacu ccaccaaccg gaacgacauc gugcagagcc     1140

uggagaaggc cgucgacaug uacaaguacg ggaagaucgc cuucguggcg auggagcgca     1200

ucacguggga cuacgacggc aucgggucca acggcaagaa ggucgaccac gacaaguucc     1260

ucgacgacgc cgagaagcac uaccugccga agaccuacac cuucgacaac gggaccuuca     1320

ucauccgggc cggcgacaag gugagcgagg agaagaucaa gcgccuguac ugggccuccc     1380

gggaggucaa gagccaguuc caccgcgugg ugggcaacga caaggcccuc gaggugggga     1440

acgcggacga cguccugacg augaagaucu ucaacucccc cgaggaguac aaguucaaca     1500

ccaacaucaa cggcgugagc accgacaacg ggggccugua caucgagccc cgggggaccu     1560

ucuacacgua cgagcgcacg ccccagcagu ccaucuucag ccucgaggag cuguuccggc     1620

acgaguacac ccacuaccug caggcccgcu accucgugga cggccugugg ggccaggggc     1680

cguucuacga gaagaaccgg cugaccuggu ucgacgaggg caccgccgag uucuucgccg     1740

gguccacccg caccagcggc guccuccccc ggaaguccau ccugggguac cuggcgaagg     1800

acaaggugga ccaccgcuac agccucaaga agacccugaa cuccggcuac gacgacagcg     1860

acuggauguu cuacaacuac ggcuucgccg uggcccacua ccuguacgag aaggacaugc     1920

ccacguucau caagaugaac aaggccaucc ucaacaccga cgucaagagc uacgacgaga     1980

ucaucaagaa gcuguccgac gacgccaaca agaacaccga guaccagaac cacauccagg     2040

agcuggcgga caaguaccag ggggccggca ucccccuggu gagcgacgac uaccucaagg     2100

accacgggua caagaaggcc uccgaggugu acagcgagau cuccaaggcc gccagccuga     2160

ccaacaccuc cgucacggcg gagaaguccc aguacuucaa caccuucacc cugcgcggca     2220

ccuacacggg cgagaccagc aagggggagu ucaaggacug ggacgagaug agcaagaagc     2280

ucgacggcac ccuggagucc cuggccaaga acagcugguc cggguacaag acccucacgg     2340

ccuacuucac caacuaccgg gugaccagcg acaacaaggu gcaguacgac gucguguucc     2400

acggcgugcu gaccgacaac gccgacaucu ccaacaacaa ggccccgauc gcgaagguca     2460

cggggcccag caccggcgcc gugggccgca acaucgaguu cuccgggaag gacagcaagg     2520

acgaggacgg caagaucgug agcuacgacu gggacuucgg ggacggcgcc accucccggg     2580

ggaagaacag cguccacgcc uacaagaagg cgggcaccua caacgugacg cugaagguga     2640

ccgacgacaa gggcgccacc gccaccgagu ccuucacgau cgagaucaag aacgaggaca     2700

ccaccacccc caucacgaag gagauggagc ccaacgacga caucaaggag gccaacgggc     2760

cgaucgucga gggcgugacc gugaaggggg accucaacgg cagcgacgac gccgacaccu     2820

ucuacuucga cgucaaggag gacggggacg ugaccaucga gcugcccuac uccggcagcu     2880

ccaacuucac guggcuggug uacaaggagg gcgacgacca gaaccacauc gcgagcggga     2940

ucgacaagaa caacuccaag gucggcaccu ucaagagcac caaggggcgc cacuacgugu     3000

ucaucuacaa gcacgacucc gccagcaaca ucuccuacag ccucaacauc aagggccugg     3060

ggaacgagaa gcugaaggag aaggagaaca acgacuccag cgacaaggcc accgugaucc     3120

ccaacuucaa cacgaccaug cagggcuccc uccugggcga cgacagccgg gacuacuacu     3180

ccuucgaggu caaggaggag ggggagguga acaucgagcu ggacaagaag gacgaguucg     3240

gcgugaccug gacccuccac cccgagagca acaucaacga ccgcaucacg uacgggcagg     3300

ucgacggcaa caaggugagc aacaagguga agcugcggcc gggcaaguac uaccugcucg     3360

ucuacaagua cuccgggagc ggcaacuacg agcugcgcgu gaacaaguga ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  3525
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt11)

<400>  3525
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugacauu caucagccuc cucuucuuau ucuccagcgc cuacuccauc gccaacacca      120

acagcgagaa guacgacuuc gaguaccuga acggccucuc uuacacggag cugaccaauc      180

ugaucaagaa caucaagugg aaccagauua acggguuauu caacuacagc accggcuccc      240

agaaguucuu cggggacaaa aaccgcgucc aggcgauuau caacgcccug caggagagcg      300

gucggaccua caccgcuaac gacaugaagg ggaucgagac cuucaccgag guucugcgcg      360

ccggcuucua ccucggcuac uacaacgacg ggcuguccua ccugaacgac cggaacuucc      420

aggacaagug cauccccgcc augaucgcga uccagaagaa cccgaacuuc aagcucggca      480

ccgccgugca ggacgagguc aucacgagcc uggggaagcu gaucggcaac gccuccgcca      540

acgcggaggu ggugaacaac ugcguccccg ugcucaagca auuccgcgaa aaccugaacc      600

aguacgcccc cgacuacgua aaggggaccg ccgucaacga gcugaucaag ggcaucgagu      660

ucgacuuuag cggcgccgcc uacgagaaag acgugaagac caugcccugg uacgggaaga      720

ucgacccguu caucaacgag cucaaggcgc ugggccugua cgggaacauc accuccgcca      780

cggagugggc cagcgacgug ggcaucuacu accucuccaa guucggccug uacucgacca      840

accggaauga caucguacag ucccuggaga aggccgugga cauguacaag uacgggaaga      900

ucgccuucgu ggcgauggag cgcaucaccu gggacuacga cgguaucggg agcaacggca      960

agaaggucga ccacgacaaa uuccucgacg acgccgagaa gcacuaccug cccaagaccu     1020

acacguucga caacggcacc uucaucaucc gggccgguga caaggugucc gaggagaaga     1080

ucaagcgccu guacugggcc agccgagagg ucaagagcca guuccaccgc guggugggca     1140

acgacaaggc ccucgaggug gggaacgcgg acgacguccu gaccaugaag aucuucaacu     1200

ccccugagga guacaaguuc aacaccaaca ucaacggcgu guccacggau aacgggggcc     1260

uguacaucga gccccggggg accuucuaca ccuaugagcg caccccgcag caguccaucu     1320

ucagccucga ggagcuguuu cggcacgagu acacgcacua ccugcaggcc cgcuacuuag     1380

uggacggccu guggggccag gggcccuucu acgagaagaa ccggcugacc ugguucgacg     1440

agggcaccgc cgaguucuuc gccgguucca cccgcacgag cggcguccuc ccccgaaagu     1500

ccauccuggg guaccuggcc aaggacaagg uggaccaccg cuacagccuc aagaagaccc     1560

ugaacuccgg cuacgacgac ucggacugga uguucuacaa cuacggcuuc gcggucgccc     1620

acuaccugua cgagaaggac augcccaccu ucaucaagau gaacaaggcc auccucaaca     1680

ccgacgugaa guccuacgac gagaucauca agaagcugag cgacgacgcc aacaagaaca     1740

cggaguacca gaaccacauc caggagcugg cggacaaaua ccagggugcc ggcaucccuc     1800

ucguguccga cgacuaccug aaggaccacg gguacaagaa ggccagcgag gucuacuccg     1860

agauuagcaa ggccgccucc cugaccaaca ccagcgugac cgcggagaag ucccaguacu     1920

ucaacacguu cacccuccgg ggcaccuaca ccggcgaaac cagcaagggg gaguucaagg     1980

acugggacga gaugagcaag aagcuggacg gcacgcugga aucccuggcc aagaacagcu     2040

gguccgggua caagacccuc accgccuauu uuaccaacua ccgcgugacg agcgacaaca     2100

agguccagua cgacguggug uuccacggcg uccugaccga caacgccgac aucuccaaca     2160

acaaggcccc caucgcgaag gugaccgggc ccagcaccgg cgccgugggc cggaacaucg     2220

aguucuccgg gaaggacucu aaggacgagg acggcaagau agucuccuac gacugggacu     2280

ucggggacgg cgccacgucc cgcgggaaga acuccgucca cgccuacaag aaggccggca     2340

ccuacaacgu gacccugaag gucaccgacg acaaaggcgc gacggccacc gagagcuuca     2400

ccaucgagau caagaacgag gacaccacga cccccaucac caaggagaug gagccgaacg     2460

acgacaucaa ggaggccaac gggcccaucg uggagggcgu gaccgucaag ggggaccuca     2520

acggcuccga cgacgcagac acguucuacu ucgaugugaa ggaggacggg gacgugacca     2580

ucgagcugcc cuacagcggc uccagcaacu ucaccuggcu ggucuacaag gagggcgacg     2640

accagaacca caucgcgucc gggaucgaca agaacaacag caaggugggc accuucaaga     2700

gcacgaaggg gcgccacuac guguucaucu acaagcacga cuccgccagc aacaucuccu     2760

acagccucaa caucaagggc cuggggaacg agaagcugaa ggagaaggag aacaacgacu     2820

ccagcgacaa ggccaccguc auccccaacu ucaacaccac caugcagggc ucccuccugg     2880

gcgacgacag ccgggacuac uacuccuucg aggugaagga ggagggggag gugaacaucg     2940

agcuggacaa gaaggacgag uucggcguca cguggacccu ccacccggaa uccaacauaa     3000

acgaccgcau caccuacggc cagguggacg ggaacaaggu guccaacaag gucaagcugc     3060

ggcccggcaa guacuaccug cucguguaca aguacagcgg guccggaaac uacgagcugc     3120

gcgugaacaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  3526
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt11)

<400>  3526
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccuc cucuuccugu ucuccagcgc cuacuccaug aagaagaaca      120

uccugaagau ccucauggac agcuacucca aggagagcaa gauccagacc guccgccggg      180

ugacguccgu gagccugcug gccgucuacc ucaccaugaa caccuccagc cuggugcugg      240

cgaagcccau cgagaacacc aacgacacgu ccaucaagaa cguggagaag cuccgcaacg      300

ccccgaacga ggagaacagc aagaaggucg aggacuccaa gaacgacaag guggagcacg      360

ugaagaacau cgaggaggcc aaggucgagc aggucgcccc cgaggucaag agcaagucca      420

cccugcggag cgccucccgc cggcgccgga agcgcaucgc gaacaccaac agcgagaagu      480

acgacuucga guaccugaac ggccucuccu acaccgagcu gacgaaccug aucaagaaca      540

ucaaguggaa ccagaucaac gggcuguuca acuacagcac cggcagccag aaguucuucg      600

gggacaagaa ccgggugcag gccaucauca acgcccugca ggaguccggc cgcaccuaca      660

ccgccaacga caugaagggg aucgagacgu ucaccgaggu gcugcgggcg ggcuucuacc      720

ucggcuacua caacgacggg cugagcuacc ugaacgaccg caacuuccag gacaagugca      780

uccccgccau gaucgccauc cagaagaacc ccaacuucaa gcucggcacc gccgugcagg      840

acgaggugau caccucccug gggaagcuga ucggcaacgc cagcgcgaac gccgaggugg      900

ugaacaacug cgucccggug cucaagcagu uccgggagaa ccugaaccag uacgcccccg      960

acuacgugaa ggggacggcc gucaacgagc ugaucaaggg caucgaguuc gacuucuccg     1020

gcgccgcgua cgagaaggac gugaagacca ugcccuggua cgggaagauc gaccccuuca     1080

ucaacgagcu caaggcccug ggccuguacg ggaacaucac cagcgccacc gagugggccu     1140

ccgacguggg caucuacuac cucagcaagu ucggccugua cuccacgaac cgcaacgaca     1200

ucguccagag ccuggagaag gccguggaca uguacaagua cgggaagauc gcguucgucg     1260

ccauggagcg gaucaccugg gacuacgacg gcaucggguc caacggcaag aagguggacc     1320

acgacaaguu ccucgacgac gccgagaagc acuaccugcc gaagaccuac accuucgaca     1380

acgggacguu caucauccgc gccggcgaca aggugagcga ggagaagauc aagcggcugu     1440

acugggccuc ccgcgagguc aagagccagu uccaccgggu ggugggcaac gacaaggcgc     1500

ucgaggucgg gaacgccgac gacgugcuga ccaugaagau cuucaacucc cccgaggagu     1560

acaaguucaa caccaacauc aacggcguga gcaccgacaa cgggggccug uacaucgagc     1620

cccgcgggac guucuacacc uacgagcgga cgccccagca guccaucuuc agccucgagg     1680

agcuguuccg ccacgaguac acccacuacc ugcaggcccg cuaccucguc gacggccugu     1740

ggggccaggg gccguucuac gagaagaacc ggcugaccug guucgacgag ggcaccgccg     1800

aguucuucgc gggguccacc cgcaccagcg gcgugcuccc ccgcaagagc auccuggggu     1860

accuggccaa ggacaaggug gaccaccggu acucccucaa gaagacgcug aacagcggcu     1920

acgacgacuc cgacuggaug uucuacaacu acggcuucgc cgucgcccac uaccuguacg     1980

agaaggacau gcccaccuuc aucaagauga acaaggccau ccugaacacc gacgucaaga     2040

gcuacgacga gaucaucaag aagcucuccg acgacgcgaa caagaacacc gaguaccaga     2100

accacaucca ggagcuggcc gacaaguacc agggggccgg caucccccug gugagcgacg     2160

acuaccucaa ggaccacggg uacaagaagg ccuccgaggu guacagcgag aucuccaagg     2220

ccgcgagccu gaccaacacg uccgugaccg ccgagaaguc ccaguacuuc aacaccuuca     2280

cccugcgggg cacguacacc ggcgagacca gcaaggggga guucaaggac ugggacgaga     2340

ugagcaagaa gcucgacggc acccuggagu cccuggccaa gaacagcugg uccggguaca     2400

agacgcucac cgccuacuuc accaacuacc gcgugaccag cgacaacaag guccaguacg     2460

acgugguguu ccacggcguc cugacggaca acgccgacau cagcaacaac aaggcgccga     2520

ucgccaaggu gaccgggccc uccaccggcg ccgugggccg gaacaucgag uucagcggga     2580

aggacuccaa ggacgaggac ggcaagaucg ucagcuacga cugggacuuc ggggacggcg     2640

ccaccucccg cgggaagaac agcgugcacg cguacaagaa ggccggcacg uacaacguga     2700

cccugaaggu caccgacgac aagggcgcca ccgccacgga guccuucacc aucgagauca     2760

agaacgagga caccaccacg cccaucacca aggagaugga gcccaacgac gacaucaagg     2820

aggccaacgg gccgaucgug gagggcguga ccgucaaggg ggaccucaac ggcagcgacg     2880

acgcggacac cuucuacuuc gacgugaagg aggacgggga cgugacgauc gagcugcccu     2940

acuccggcag cuccaacuuc accuggcugg ucuacaagga gggcgacgac cagaaccaca     3000

ucgccagcgg gaucgacaag aacaacucca aggugggcac cuucaagagc accaaggggc     3060

ggcacuacgu guucaucuac aagcacgacu ccgccagcaa caucuccuac agccucaaca     3120

ucaagggccu ggggaacgag aagcugaagg agaaggagaa caacgacucc agcgacaagg     3180

ccacggucau ccccaacuuc aacaccacca ugcagggcag ccuccugggc gacgacuccc     3240

gcgacuacua cagcuucgag gugaaggagg agggggaggu gaacaucgag cuggacaaga     3300

aggacgaguu cggcgucacc uggacgcucc accccgaguc caacaucaac gaccggauca     3360

ccuacggcca gguggacggg aacaagguga gcaacaaggu caagcugcgc ccgggcaagu     3420

acuaccugcu cguguacaag uacuccggga gcggcaacua cgagcugcgg gugaacaagu     3480

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  3527
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt11)

<400>  3527
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugaagau cauccucaac cgcggcaaga ccaugaagcg gaagugccug agcaagcgcc      120

ugaugcucgc caucaccaug gccacgaucu ucaccgugaa cuccacccug cccaucuacg      180

cggccgucga caagaacaac gccaccgccg ccgugcagaa cgagagcaag cgguacacgg      240

uguccuaccu gaagacccuc aacuacuacg accuggucga ccugcucgug aagaccgaga      300

ucgagaaccu gccggaccug uuccaguaca gcuccgacgc gaaggaguuc uacgggaaca      360

agacccgcau gagcuucauc auggacgaga ucggccggcg cgcgccccag uacacggaga      420

ucgaccacaa ggggaucccc acccucgugg aggucgugcg ggccggcuuc uaccuggggu      480

uccacaacaa ggagcugaac gagaucaaca agcgcuccuu caaggagcgg gugaucccca      540

gcauccucgc cauccagaag aacccgaacu ucaagcuggg caccgagguc caggacaaga      600

ucguguccgc caccggccug cucgccggga acgagacggc cccgcccgag guggucaaca      660

acuucacccc cauccugcag gacugcauca agaacaucga ccgcuacgcc cuggacgacc      720

ucaagagcaa ggcccuguuc aacgugcugg cggccccgac cuacgacauc accgaguacc      780

uccgggccac gaaggagaag cccgagaaca cccccuggua cggcaagauc gacggguuca      840

ucaacgagcu gaagaagcug gcccucuacg gcaagaucaa cgacaacaac uccuggauca      900

ucgacaacgg gaucuaccac aucgcgcccc ugggcaagcu gcacagcaac aacaagaucg      960

gcaucgagac ccucaccgag gugaugaagg ucuacccgua ccuguccaug cagcaccucc     1020

agagcgccga ccagaucaag cgccacuacg acuccaagga cgccgagggg aacaagaucc     1080

cccuggacaa guucaagaag gagggcaagg agaaguacug ccccaagacg uacaccuucg     1140

acgacgggaa ggugaucauc aaggccggcg cccgggugga ggaggagaag gucaagcgcc     1200

uguacugggc cagcaaggag gugaacuccc aguucuuccg gguguacggc aucgacaagc     1260

cccuggagga ggggaacccg gacgacaucc ucaccauggu caucuacaac agccccgagg     1320

aguacaagcu gaacuccgug cuguacggcu acgacaccaa caacgggggc auguacaucg     1380

agcccgaggg gacguucuuc accuacgagc gcgaggcgca ggagagcacc uacacccucg     1440

aggagcuguu ccggcacgag uacacgcacu accugcaggg ccgcuacgcc gugcccggcc     1500

agugggggcg gaccaagcuc uacgacaacg accgccugac cugguacgag gagggcgggg     1560

ccgagcuguu cgccggcagc acccggacgu ccgggauccu cccgcgcaag agcaucgucu     1620

ccaacaucca caacaccacc cgcaacaacc gguacaagcu gagcgacacc gugcacucca     1680

aguacggcgc cagcuucgag uucuacaacu acgcgugcau guucauggac uacauguaca     1740

acaaggacau gggcauccug aacaagcuca acgaccuggc caagaacaac gacgucgacg     1800

gguacgacaa cuacauccgc gaccugucca gcaacuacgc ccugaacgac aaguaccagg     1860

accacaugca ggagcggauc gacaacuacg agaaccucac ggugcccuuc guggccgacg     1920

acuaccuggu ccgccacgcg uacaagaacc ccaacgagau cuacuccgag aucagcgagg     1980

uggccaagcu gaaggacgcc aaguccgagg ugaagaaguc ccaguacuuc agcaccuuca     2040

cccuccgggg cagcuacacc gggggcgccu ccaaggggaa gcuggaggac cagaaggcca     2100

ugaacaaguu caucgacgac agccugaaga agcucgacac cuacuccugg agcggcuaca     2160

agacgcugac cgcguacuuc accaacuaca aggucgacuc cagcaaccgc gugaccuacg     2220

acguggucuu ccacggcuac cugcccaacg agggggacag caagaacucc cucccguacg     2280

gcaagaucaa cgggacguac aagggcaccg agaaggagaa gaucaaguuc agcuccgagg     2340

gcagcuucga ccccgacggg aagaucgugu ccuacgagug ggacuucggc gacgggaaca     2400

agagcaacga ggagaacccc gagcacuccu acgacaaggu gggcaccuac accgucaagc     2460

ugaaggugac ggacgacaag ggggagagcu ccgugagcac caccaccgcc gagaucaagg     2520

accuguccga gaacaagcuc cccgucaucu acaugcacgu gcccaagagc ggcgcccuga     2580

accagaaggu ggucuucuac ggcaagggga cguacgaccc cgacggcucc aucgccgggu     2640

accaguggga cuucggcgac gggagcgacu ucuccagcga gcagaacccc ucccacgugu     2700

acaccaagaa gggcgaguac accgugaccc ugcgggucau ggacagcagc ggccagaugu     2760

ccgagaagac gaugaagauc aagaucaccg acccggugua ccccaucggg accgagaagg     2820

agcccaacaa cagcaaggag accgccuccg gccccaucgu gccggggauc cccgucagcg     2880

gcacgaucga gaacaccucc gaccaggacu acuucuacuu cgacgugauc acccccgggg     2940

aggugaagau cgacaucaac aagcucggcu acggcggggc gaccuggguc guguacgacg     3000

agaacaacaa cgccgugagc uacgccacgg acgacggcca gaaccugucc gggaaguuca     3060

aggccgacaa gcccggccgc uacuacaucc accuguacau guucaacggg agcuacaugc     3120

cguaccggau caacaucgag ggcuccgucg gccgcugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  3528
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt11)

<400>  3528
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

gcaagugccu gagcaagcgg cucaugcugg ccaucaccau ggccaccauc uucacgguga      120

acuccacccu gcccaucuac gcggccgucg acaagaacaa cgccaccgcc gccgugcaga      180

acgagagcaa gcgcuacacc guguccuacc ucaagacgcu gaacuacuac gaccuggucg      240

accuccuggu gaagaccgag aucgagaacc ugccggaccu cuuccaguac agcuccgacg      300

cgaaggaguu cuacggcaac aagacccgga ugagcuucau cauggacgag aucgggcgcc      360

gggcgcccca guacaccgag aucgaccaca agggcauccc cacgcuggug gaggucgugc      420

gcgccggguu cuaccugggc uuccacaaca aggagcucaa cgagaucaac aagcgguccu      480

ucaaggagcg cgugaucccc agcauccugg ccauccagaa gaacccgaac uucaagcugg      540

ggaccgaggu ccaggacaag aucguguccg ccaccggccu ccuggccggc aacgagaccg      600

ccccgcccga gguggucaac aacuucacgc ccauccugca ggacugcauc aagaacaucg      660

accgguacgc ccucgacgac cucaagagca aggcccuguu caacgugcuc gcggccccga      720

ccuacgacau caccgaguac cugcgcgcca ccaaggagaa gcccgagaac acgcccuggu      780

acgggaagau cgacggcuuc aucaacgagc ugaagaagcu cgcccuguac gggaagauca      840

acgacaacaa cuccuggauc aucgacaacg gcaucuacca caucgcgccc cuggggaagc      900

uccacagcaa caacaagauc ggcaucgaga cccugaccga ggugaugaag gucuacccgu      960

accuguccau gcagcaccuc cagagcgccg accagaucaa gcggcacuac gacuccaagg     1020

acgccgaggg caacaagauc ccccuggaca aguucaagaa ggaggggaag gagaaguacu     1080

gccccaagac cuacacguuc gacgacggca aggugaucau caaggccggg gcccgcgugg     1140

aggaggagaa ggucaagcgg cuguacuggg ccagcaagga ggugaacucc caguucuucc     1200

gcguguacgg caucgacaag ccccucgagg agggcaaccc ggacgacauc cugaccaugg     1260

ucaucuacaa cagccccgag gaguacaagc ugaacuccgu gcucuacggg uacgacacca     1320

acaacggcgg gauguacauc gagcccgagg gcaccuucuu cacguacgag cgggaggcgc     1380

aggagagcac cuacacccug gaggagcugu uccgccacga guacacccac uaccuccagg     1440

ggcgguacgc cgugcccggc caguggggcc gcacgaagcu guacgacaac gaccggcuga     1500

ccugguacga ggagggcggg gccgagcugu ucgccgggag cacccgcacc uccggcaucc     1560

ugccgcgcaa gagcaucguc uccaacaucc acaacacgac ccggaacaac cgcuacaagc     1620

ugagcgacac cgugcacucc aaguacgggg ccagcuucga guucuacaac uacgcgugca     1680

uguucaugga cuacauguac aacaaggaca ugggcauccu caacaagcug aacgaccugg     1740

ccaagaacaa cgacgucgac ggcuacgaca acuacauccg ggaccucucc agcaacuacg     1800

cccugaacga caaguaccag gaccacaugc aggagcgcau cgacaacuac gagaaccuga     1860

ccgugcccuu cguggccgac gacuaccugg uccggcacgc guacaagaac cccaacgaga     1920

ucuacuccga gaucagcgag guggccaagc ucaaggacgc caaguccgag gugaagaagu     1980

cccaguacuu cagcacguuc acccugcgcg ggagcuacac cggcggggcc uccaagggca     2040

agcuggagga ccagaaggcc augaacaagu ucaucgacga cagccucaag aagcuggaca     2100

ccuacuccug gagcggguac aagacccuga cggcguacuu caccaacuac aaggucgacu     2160

ccagcaaccg ggugaccuac gacguggucu uccacggcua ccuccccaac gagggcgaca     2220

gcaagaacuc ccugccguac gggaagauca acggcaccua caaggggacg gagaaggaga     2280

agaucaaguu cagcuccgag ggcagcuucg accccgacgg caagaucgug uccuacgagu     2340

gggacuucgg ggacggcaac aagagcaacg aggagaaccc cgagcacucc uacgacaagg     2400

uggggaccua caccgucaag cugaagguga ccgacgacaa gggcgagagc uccgugagca     2460

cgaccaccgc cgagaucaag gaccucuccg agaacaagcu gcccgucauc uacaugcacg     2520

ugcccaagag cggggcccug aaccagaagg uggucuucua cggcaagggc accuacgacc     2580

ccgacggguc caucgccggc uaccaguggg acuucgggga cggcagcgac uucuccagcg     2640

agcagaaccc cucccacgug uacacgaaga agggggagua caccgugacc cuccgcguca     2700

uggacagcag cggccagaug uccgagaaga ccaugaagau caagaucacg gacccggugu     2760

accccaucgg caccgagaag gagcccaaca acagcaagga gaccgccucc gggcccaucg     2820

ugccgggcau ccccgucagc gggaccaucg agaacacguc cgaccaggac uacuucuacu     2880

ucgacgugau cacccccggc gaggugaaga ucgacaucaa caagcugggg uacggcggcg     2940

cgaccugggu cguguacgac gagaacaaca acgccgugag cuacgccacc gacgacgggc     3000

agaaccuguc cggcaaguuc aaggccgaca agcccgggcg guacuacauc caccucuaca     3060

uguucaacgg cagcuacaug ccguaccgca ucaacaucga gggguccguc ggccggugag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  3529
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt11)

<400>  3529
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccug cuguuccugu ucuccagcgc cuacuccguc cagaacgaga      120

gcaagcgcua caccgugucc uaccugaaga cgcucaacua cuacgaccug guggaccugc      180

ucgucaagac cgagaucgag aaccugcccg accuguucca guacagcucc gacgccaagg      240

aguucuacgg caacaagacc cggaugagcu ucaucaugga cgagaucggg cgccgggcgc      300

cgcaguacac cgagaucgac cacaagggca uccccacgcu cguggaggug guccgcgccg      360

gguucuaccu gggcuuccac aacaaggagc ugaacgagau caacaagcgg uccuucaagg      420

agcgcgugau ccccagcauc cucgccaucc agaagaaccc caacuucaag cuggggaccg      480

aggugcagga caagaucguc uccgccaccg gccugcucgc cggcaacgag accgcgccgc      540

ccgagguggu gaacaacuuc acgcccaucc ugcaggacug caucaagaac aucgaccggu      600

acgcccugga cgaccucaag agcaaggccc uguucaacgu ccuggccgcg cccaccuacg      660

acaucaccga guaccuccgc gccaccaagg agaagccgga gaacacgccc ugguacggga      720

agaucgacgg cuucaucaac gagcugaaga agcuggcccu cuacgggaag aucaacgaca      780

acaacuccug gaucaucgac aacggcaucu accacaucgc gccccugggg aagcugcaca      840

gcaacaacaa gaucggcauc gagacccuca ccgaggugau gaagguguac cccuaccugu      900

ccaugcagca ccuccagagc gccgaccaga ucaagcggca cuacgacucc aaggacgccg      960

agggcaacaa gaucccgcuc gacaaguuca agaaggaggg gaaggagaag uacugcccca     1020

agaccuacac guucgacgac ggcaagguca ucaucaaggc cggggcccgc guggaggagg     1080

agaaggugaa gcggcuguac ugggccagca aggaggucaa cucccaguuc uuccgcgugu     1140

acggcaucga caagccccug gaggagggca accccgacga cauccucacc auggugaucu     1200

acaacagccc ggaggaguac aagcugaaca gcguccugua cggguacgac accaacaacg     1260

gcgggaugua caucgagccc gagggcaccu ucuucacgua cgagcgggag gcccaggagu     1320

ccaccuacac ccucgaggag cuguuccgcc acgaguacac ccacuaccug caggggcggu     1380

acgcggugcc cggccagugg ggccgcacga agcucuacga caacgaccgg cugaccuggu     1440

acgaggaggg cggggccgag cuguucgccg ggagcacccg caccuccggc auccuccccc     1500

gcaagagcau cguguccaac auccacaaca cgacccggaa caaccgguac aagcugagcg     1560

acaccgucca cuccaaguac ggggccagcu ucgaguucua caacuacgcc ugcauguuca     1620

uggacuacau guacaacaag gacaugggca uccugaacaa gcucaacgac cuggcgaaga     1680

acaacgacgu ggacggcuac gacaacuaca uccgcgaccu guccagcaac uacgcccuca     1740

acgacaagua ccaggaccac augcaggagc gcaucgacaa cuacgagaac cugaccgucc     1800

cguucguggc cgacgacuac cuggugcggc acgccuacaa gaaccccaac gagaucuacu     1860

ccgagaucag cgaggucgcc aagcugaagg acgcgaaguc cgaggugaag aagucccagu     1920

acuucagcac guucacccuc cgcgggagcu acaccggcgg ggccuccaag ggcaagcugg     1980

aggaccagaa ggccaugaac aaguucaucg acgacagccu gaagaagcuc gacaccuacu     2040

ccuggagcgg guacaagacg cugaccgccu acuucaccaa cuacaaggug gacagcucca     2100

accgggucac cuacgacgug guguuccacg gcuaccugcc caacgagggc gacagcaaga     2160

acucccuccc cuacgggaag aucaacggca ccuacaaggg gacggagaag gagaagauca     2220

aguucagcuc cgagggcagc uucgacccgg acggcaagau cgucuccuac gagugggacu     2280

ucggggacgg caacaagagc aacgaggaga accccgagca cuccuacgac aaggugggga     2340

ccuacaccgu gaagcugaag gucaccgacg acaagggcga gagcuccgug agcacgacca     2400

ccgcggagau caaggaccug uccgagaaca agcuccccgu gaucuacaug cacgucccca     2460

agagcggggc ccugaaccag aagguggugu ucuacggcaa gggcaccuac gacccggacg     2520

gguccaucgc cggcuaccag ugggacuucg gggacggcag cgacuucucc agcgagcaga     2580

accccagcca cgucuacacg aagaaggggg aguacaccgu gacccugcgc gugauggacu     2640

ccagcggcca gauguccgag aagaccauga agaucaagau cacggacccc gucuacccga     2700

ucggcaccga gaaggagccc aacaacagca aggagaccgc cuccgggccc aucgugcccg     2760

gcaucccggu gagcgggacc aucgagaaca cguccgacca ggacuacuuc uacuucgacg     2820

ucaucacccc cggcgaggug aagaucgaca ucaacaagcu cggguacggc ggcgccaccu     2880

ggguggucua cgacgagaac aacaacgcgg ugagcuacgc caccgacgac gggcagaacc     2940

uguccggcaa guucaaggcc gacaagcccg ggcgguacua cauccaccug uacauguuca     3000

acggcagcua caugcccuac cgcaucaaca ucgagggguc cgugggccgg ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3530
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt11)

<400>  3530
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

gggugaccuu caucagccuc uuauuccugu uuuccagugc cuacuccaug aagcgcaagu      120

gccugagcaa gcggcucaug cuggccauca ccauggcgac gaucuucacc gucaacucca      180

cccugcccau cuacgccgcc guggacaaga acaacgccac cgccgcgcgc cggcgccgga      240

agcgcgugca gaacgagagc aagcgguaca cggucuccua ccucaagacc cugaacuacu      300

acgaccuggu ggaccuccug gugaagaccg agaucgagaa ccugccggac cucuuccagu      360

acagcucaga cgccaaggag uucuacggca acaagacccg caugagcuuc aucauggacg      420

agaucgggcg gcgcgcgccc caguacacgg agaucgacca caagggcauu cccacccugg      480

ucgagguggu gcgggccggg uucuaccugg gcuuccacaa caaggagcuc aaugagauca      540

acaagcgcuc cuucaaggag cgagucaucc caagcauccu ggccauccag aagaacccga      600

acuucaagcu ggggaccgag gugcaggaca agaucguguc cgccaccggc cuccucgccg      660

gcaacgagac ggccccgccc gaggucguga auaacuucac ccccauccug caggacugca      720

ucaagaacau cgaccgcuac gcccucgacg accucaagag caaggcgcug uucaacgucc      780

uggcagcccc gacauacgac aucaccgagu accuccgggc cacuaaggag aagcccgaga      840

acacccccug guacgggaag aucgacggcu ucaucaacga gcugaagaaa cucgcccugu      900

acgggaagau caacgacaac aacuccugga ucaucgacaa cggcaucuac cacaucgcgc      960

cccuggggaa gcuccacagc aacaacaaga ucggcaucga gaccuugacc gaggucauga     1020

agguguaccc guaccugucc augcagcacc uccaaagcgc cgaccagauc aagcgccacu     1080

acgacuccaa ggacgccgag ggcaacaaga ucccccuuga caaguucaag aaggagggga     1140

aggagaaaua cugccccaag acguacaccu ucgacgacgg caaggugauc aucaaggccg     1200

gggcccgggu cgaggaggag aaggugaagc gguuauacug ggcgucaaaa gaggugaaca     1260

gccaguucuu ccgggucuac ggcaucgaca agccccucga ggagggcaac ccggacgaca     1320

uccugaccau ggugaucuac aacucccccg aggaguacaa gcugaacagc gugcucuacg     1380

gguacgacac aaacaacggc ggaauguaca ucgagcccga gggcacguuc uucacguacg     1440

agcgcgaggc ccaggagucc accuacaccc uggaggagcu guuccggcac gaguacacgc     1500

acuaccucca ggggagauac gccguccccg gccagugggg ccgcaccaag cuguacgaca     1560

acgaccggcu gaccugguac gaggagggag gggccgagcu guucgccggg agcacccgca     1620

cguccggcau ccugccgcgc aagagcaucg uuuccaacau ccauaacacc acccggaaca     1680

acagauacaa gcugagcgac accguccacu ccaaguacgg ggcgagcuuc gaguuuuaca     1740

acuacgccug uauguucaug gacuacaugu acaacaagga uaugggcaua cucaacaagc     1800

ugaacgaccu ggccaagaau aacgacgugg acggcuacga caacuacauc cgcgaccugu     1860

caagcaacua cgcccucaac gacaaguacc aggaccacau gcaggagcgg aucgacaacu     1920

acgagaaccu gacggugccc uucgucgcgg acgacuaccu ggugcgucac gccuacaaga     1980

accccaacga gaucuacucu gagaucagug agguggccaa gcucaaggac gccaagucag     2040

aggucaagaa gucccaguac uucagcaccu ucacccugcg ggggagcuau accggcgggg     2100

ccuccaaggg caagcuggag gaccagaagg ccaugaacaa guucaucgac gacagccuca     2160

agaagcugga caccuacagc ugguccgggu acaagacgcu gaccgcguac uucaccaacu     2220

acaaggugga uagcuccaac cgcguaaccu acgacgucgu guuccacggc uaccucccca     2280

acgagggcga cagcaagaac ucccugccgu acgggaagau caacggcacg uacaagggga     2340

ccgagaagga gaaaaucaag uucagcuccg agggcuccuu cgaccccgac ggcaagaucg     2400

uguccuacga gugggacuuc ggggacggca acaagagcaa cgaggagaac cccgaacacu     2460

ccuacgacaa ggucgggacc uacaccguga agcugaaggu gacggacgac aagggcgaga     2520

gcuccgucuc uaccaccacc gccgagauca aggaccucuc cgagaacaag cugcccguga     2580

ucuacaugca cgugcccaag ucaggggccc ugaaccaaaa ggucguguuu uacggcaagg     2640

gcacguacga ccccgacggg uccauagccg gcuaccagug ggacuucggg gacggcagcg     2700

acuucagcuc cgagcagaac cccagccacg uguacaccaa gaagggggag uacaccguca     2760

cccucagggu gauggacucc agcggccaga uguccgagaa gacgaugaag aucaagauca     2820

ccgauccggu guaccccauc ggcaccgaga aggagccgaa caacagcaag gagaccgcgu     2880

ccgggcccau cgucccgggc auccccguga gcgggacgau cgagaacacc uccgaccagg     2940

acuacuucua cuucgacgug aucacccccg gcgaggucaa gaucgauauc aacaagcugg     3000

gguacggcgg cgccaccugg gugguguacg acgagaacaa caacgccguc agcuacgcua     3060

cggacgacgg gcagaaccug uccggcaagu ucaaggccga caagcccggg cgguacuaca     3120

uccaccucua cauguucaac ggcagcuaca ugccguaccg gaucaacauc gagggguccg     3180

uaggccgaug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  3531
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt11)

<400>  3531
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauacu auucgccugc cuccucggcg ccgccuucgc caugccccua cccccccacc      120

ccggccaccc cggcuacauc aacuucucau acgaaguccu caccccccuc aaaugguacc      180

aaucaauccg cccccccuac cccuccuacg gcuacgaacc caugggaggc uggcuccacc      240

accaaaucau ccccguccuc ucccaacaac acccccccac ccacacccuc caaccccacc      300

accacauccc cgucgucccc gcccaacaac ccgucauccc ccaacaaccc augaugcccg      360

uccccggcca acacucaaug acccccaucc aacaccacca acccaaccuc cccccccccg      420

cccaacaacc cuaccaaccc caacccgucc aaccccaacc acaccaacca augcaacccc      480

aaccccccgu ccaccccaug caaccccucc ccccccaacc cccccuaccc cccauguucc      540

ccaugcaacc ccuccccccc augcuccccg accucacccu cgaagccugg cccuccaccg      600

acaaaaccaa acgcgaagaa gucgacuaag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  3532
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt11)

<400>  3532
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc cucacccccc      120

ucaaauggua ccaauccauc cgcccccccu accccuccua cggcuacgaa cccaugggcg      180

gcugguaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  3533
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt11)

<400>  3533
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc cucacccccc      120

ucaaauggua ccaauccauc cgcccccccc ccaugcuccc cgaccucacc cucgaagccu      180

ggcccuccac cgacaaaacc aaacgcgaag aagucgacua aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  3534
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt11)

<400>  3534
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc ccgcacccuc guccuccucc ucuccggcgc ccucgcccuc acccaaaccu      120

gggccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaucca uccgcccccc cuaccccucc uacggcuacg      240

aacccauggg cggcugguaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  3535
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt11)

<400>  3535
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc ccgcacccuc guccuacucc ucuccggcgc ccucgcccuc acccaaaccu      120

gggccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaucca uccgcccccc ccccaugcuc cccgaccuca      240

cccucgaagc cuggcccucc accgacaaaa ccaaacgcga agaagucgac uaaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  3536
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt11)

<400>  3536
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cucgucggcg ccgccuucgc aaugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgaaguccu caccccacuc aaaugguacc      180

aauccaugau ccgcccaccc uacucauccu acggcuacga accaaugggc ggcuggcucc      240

accaccaaau cauccccguc guaucccaac aacacccccu cacccacacc cuccaauccc      300

accaccacau ccccgucguc cccgcacaac aaccccgcgu ccgccaacaa gcccucaugc      360

ccguccccgg ccaacaaucc augaccccca cccaacacca ccaacccaac cucccccucc      420

ccgcccaaca acccuuccaa ccccaacccg uccaacccca accccaccaa cccaugcaac      480

cccaaccccc aguccaaccc augcaacccc uccuccccca acccccccuc ccccccaugu      540

ucccacuccg accccucccc cccauccuac ccgaccucca ccuugaagcc uggcccgcca      600

ccgacaaaac caaacaagaa gaagucgacu aaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  3537
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt11)

<400>  3537
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc cucacccccc      120

ucaaauggua ccaauccaug auccgccccc ccuacuccuc cuacggcuac gaacccaugg      180

gcggcuggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3538
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt11)

<400>  3538
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc cucacccccc      120

ucaaauggua ccaauccaug auccgccccc cccccauccu ccccgaccuc caccucgaag      180

ccuggcccgc caccgacaaa accaaacaag aagaagucga cuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3539
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt11)

<400>  3539
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc ccgcacccuc guccuccucc ucuccggcgc ccucgcccuc acccaaaccu      120

gggccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaucca ugauccgccc ccccuacucc uccuacggcu      240

acgaacccau gggcggcugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3540
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt11)

<400>  3540
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc ccgcacccuc guccuccucc ucuccggcgc ccucgcccuc acccaaaccu      120

gggccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaucca ugauccgccc cccccccauc cuccccgacc      240

uccaccucga agccuggccc gccaccgaca aaaccaaaca agaagaaguc gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3541
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt11)

<400>  3541
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugu cuccucggcg ccgccuucuc caugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgaaguccu caccccccuc aaaugguacc      180

aaaacaugau ccgacacccc uacaccuccu acggcuacga acccaugggc ggcuggcucc      240

accaccaaau cauccccguc gucucccaac aaacccccca aucccacgcc cuucaacccc      300

accaccacau ccccaugguc cccgcccaac aacccggcau accccaacaa cccaugaugc      360

cccucccugg ccaacacucc augaccccca cccaacacca ccaacccaac cucccccucc      420

ccgcccaaca acccuuccaa ccccaacccg uccaacccca accccaccaa ccccuccaac      480

cccaaucccc caugcacccc auccaacccc uccuccccca accaccccua ccccccaugu      540

ucuccaugca aucccuccuc cccgaccucc cccucgaagc cuggcccgcc accgacaaaa      600

caaaacguga agaagucgac uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3542
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt11)

<400>  3542
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc cucacccccc      120

ucaaauggua ccaaaacaug auccgccacc ccuacaccuc cuacggcuac gaacccaugg      180

gcggcuggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3543
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt11)

<400>  3543
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

ucccccccca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc cucacccccc      120

ucaaauggua ccaaaacaug auccgccacc ccucccuccu ccccgaccuc ccccucgaag      180

ccuggcccgc caccgacaaa accaaacgcg aagaagucga cuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3544
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt11)

<400>  3544
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc ccgcacccuc guccuccucc ucuccggcgc ccucgcccuc acccaaaccu      120

gggccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaaaca ugauccgcca ccccuacacc uccuacggcu      240

acgaacccau gggcggcugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3545
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt11)

<400>  3545
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ucauggcccc ccgcacccuc guccuccucc ucuccggcgc ccucgcccuc acccaaaccu      120

gggccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaaaca ugauccgcca ccccucccuc cuccccgacc      240

ucccccucga agccuggccc gccaccgaca aaaccaaacg cgaagaaguc gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3546
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt11)

<400>  3546
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cuccucggcg ccgccuucuc caugccccuc cccccccacc      120

ccggccaccc cggauacauc aacuucuccu acauccgaca ccccuacacc uccuacggcu      180

acgaacccau gggcggcugg cuccaccacc aaaucauccc cgucgucucc caacaaaccc      240

cccaauccca cgcccuccaa ccacaccacc acauccccau gguccccgcc caacaacccg      300

gcauccccca acaacccaug augccccucc ccggccaaca cuccaugacc cccacccaac      360

accaccaacc caaccucccc cuucccgccc aacaacccuu ccaaccccaa cccguccaac      420

cccaacccca ccaaccccua caaccccaau cccccaugca ccccauccaa ccccuccucc      480

cccaaccccc ccuacccccc auguucucca ugcaaucccu ccuccccgac cucccccucg      540

aagccuggcc cgccaccgac aaaaccaaac gcgaagaagu cgacuaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  3547
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt11)

<400>  3547
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggaucuu cuucgccugc cuccucggcg ccucccucgc caugccccuc ccaccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgaaguccu cacaccccuc aaaugguacc      180

aaaacaugau ccgccacccc uacaccuccu acggcuacga acccaugggc ggcuggcucc      240

accaccaaau cauccccguc gucucucaac aaacacccca aucccacgcc cuccaacccc      300

accaccacau ccccaugguc cccgcccaac aacccggcau accccaacaa cccaugaugc      360

cccuccccgg ccaacacucc augaccccca cccaacacca ccaacccaac cucccccucc      420

ccgcccaaca acccuuccaa ccccaacccg uccaacccca accccaccaa ccccuccaac      480

cccaaucccc caugcacccc auccaacccc uacuccccca accaccccua ccacccaugu      540

ucuccaugca aucccuccuc cccgaccucc cccucgaagc cuggcccgcc accgacaaaa      600

ccaaacgcga agaagucgac uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3548
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt11)

<400>  3548
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cuccucggcg ccgccuucuc caugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgaaguccu caccccccuc aaaugguacc      180

aaaacaugau ccgccacccc ucccuccucc ccgaccuccc ccucgaagcc uggcccgcca      240

ccgacaaaac caaacgcgaa gaagucgacu aaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  3549
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt11)

<400>  3549
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

ccuggauccu cuucgccugc cuccucggag ccgccuucuc caugccccua cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgaagaccu uuaccucgaa gccauccgca      180

ucgaccgcac cgccuucguc cucacccccc uaaaauggua ccaaaacaug auccgccacc      240

ccuacaccuc cuacggcuac gaacccaugg gcggcuggcu ccaccaccaa aucauccccg      300

ucgucuccca acaaaccccc caaucccacg cccuccaacc ccaccaccac auccccaugg      360

uccccgccca acaacccggc aucccccaac aacccaugau gccccucccc ggccaacacu      420

ccaugacccc cacccaacac caccaaccca accucccccu ccccgcccaa caacccuucc      480

aaccccaacc cguacaaccc cagccccacc aaccccuuca accccaaucc cccaugcacc      540

ccauccaacc ccuccucccc caaccccccc uaccccccau guucuccaug caaucccucc      600

uccccgaccu cccccucgaa gccuggcccg ccaccgacaa aaccaaacgc gaagaagucg      660

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  3550
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt11)

<400>  3550
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

ccuggauccu cuucgccugc cuccucggcg cagccuucuc caugccccuc cccccccacc      120

ccggccaccc cggcuacauc aacuucuccu acgaaguccu caccccccua aaaugguacc      180

aaaacaugau ccgccacccc acaccccaau cacacgcccu ccaaccccac caccacaucc      240

ccaugguccc cgcacaacaa cccggcaucc cccaacaacc caugaugccc cuccccggcc      300

aacacuccau gacacccacc caacaccacc aacccaaccu accccucccc gcccaacaac      360

ccuuccaacc ccaacccguc caaccccaac cccaccaacc ccuccaaccc caauccccca      420

ugcaccccau ccaaccccuc cucccccaac ccccccuccc acccauguuc uccaugcaau      480

cccuccuccc cgaccuccca cucgaagccu ggcccgccac cgacaaaacc aaacgcgaag      540

aagucgacua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  3551
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt11)

<400>  3551
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

uacccccaca ccccggccac cccggcuaca ucaacuucuc cuacgaaguc cucaccccac      120

ucaaauggua ccaaaacaug auccgccacc ccuacaccuc cuacggcuac gaacccaugg      180

gcggcuggcu ccaccaccaa aucauccccg ucgucuccca acaaacccca caaucccacg      240

cccuccaacc ccaccaccac auccccaugg uccccgccca acaacccggc aucccccaac      300

aacccaugau gccccucccc ggccaacacu ccaugacccc cacccaacac caccaaccca      360

accuaccccu ccccgcccaa caacccuucc aaccccaacc aguccaaccc caaccccacc      420

aaccccucca accccaaucc cccaugcacc caauccaacc ccuacucccc caaccucccc      480

uaccacccau guucuccaug caaucccucc uccccgaccu cccccucgaa gccuggcccg      540

ccaccgacaa aaccaaacgc gaagaagucg acuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  3552
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt11)

<400>  3552
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

gaguugcccg ccuaccacua cuacuagguc uccucuuacu cccgcgaccc ggccgcccac      120

ucgaccuagc agacuacaca uacgaccucg cagaagaaga cgacucagaa ccacuaaacu      180

acaaagaucc cugcaaagcc gcggcauucc ucggagacau agcccuggac gaagaagauc      240

uacgagcauu ccagguccaa caagcaguag accuccggcg acacacagcu cgcaaaucgu      300

ccaucaaagc ggccguccca ggcaacacaa guaccccuuc cugccagucc accaacgguc      360

aaccccaacg gggagccugc ggacgcuggc guggcagguc acgaucccgg cgagcagcca      420

ccagcagacc ggaacgagua uggcccgacg gggucauccc auucguaauc ggugggaacu      480

ucacgggauc gcaacgagca guauuccgac aggccaugcg ccacugggaa aaacacacau      540

gcgucaccuu ccucgaacgc acagacgaag acagcuacau agucuucaca uacagaccau      600

gcggaugcug caguuacguc ggacggagag gcggcggccc gcaagcaaua ucgauaggga      660

aaaacugcga caaauucggc auagucgucc acgaacuagg gcaugucgua ggguucuggc      720

acgagcacac caggcccgac cgagaccgcc acguaagcau aguccgcgaa aacauccaac      780

ccggacagga auacaacuuc cucaagaugg aaccccaaga agucgagucg cugggggaaa      840

cauacgacuu cgacuccaua augcacuacg cccgaaacac cuucagccga gguaucuucc      900

ucgacacaau cguccccaag uacgaaguca acggcgucaa acccccaaua ggccaacgga      960

cccgacucuc aaaaggugac aucgcucagg cccgcaaacu guauaagugc cccgccugug     1020

gggagacccu acaggacagc acgggcaacu ucagcucccc ugaauacccc aacggcuaca     1080

gcgcacacau gcacugcguc uggcgcauca gugucacccc aggagagaaa aucauccuca     1140

acuucaccuc acucgaucuc uaccgaagca gacucuguug guacgacuac guggaggucc     1200

gagacggguu cuggcgcaaa gcaccgcucc gcggccgcuu cugcggcucu aaacuucccg     1260

aacccauugu cagcaccgac ucgagacucu gggucgaguu caggaguucc agcaacuggg     1320

uaggcaaagg auucuuugca gucuacgaag ccauaugcgg cggcgacguc aagaaagacu     1380

acggccacau ccagucccca aacuacccag acgacuaccg ccccuccaaa gucugcauau     1440

ggaggauaca aguaucagaa ggguuucacg ucggacugac auuccaaagu uucgaaauag     1500

aacgucacga cucaugcgcg uacgacuacc uggaaguacg cgacggccau uccgaaagca     1560

gcacacuaau aggccgguac uguggcuacg aaaagcccga cgacauaaaa ucaacaucaa     1620

gcagacugug gcuaaaguuc gucucggacg gaagcauaaa caaagcagga uucgcaguga     1680

acuucuuuaa ggaagucgac gaauguucgc gcccaaacag gggaggcugc gaacaaagau     1740

gccuuaacac acugggguca uauaagugca gcugcgaccc cggauacgag cuugcaccag     1800

acaagcgaag augugaggcc gccugcggag gcuuccucac aaaacugaac ggauccauca     1860

caucacccgg auggccaaaa gaguaucccc cgaauaaaaa cugcauaugg cagcuaguag     1920

cgccaaccca auaccggauc agccuccagu ucgacuucuu cgaaaccgaa ggcaacgacg     1980

ugugcaaaua cgacuucguc gagguacgca gcggucuuac cgcggacuca aaacugcacg     2040

gcaaauucug cggcagcgaa aaaccagaag uaaucaccag ccaauacaac aacaugagag     2100

ucgaauuuaa aucagacaac accguaucca agaaaggcuu caaagcccac uucuuuuccg     2160

auaaagacga augcaguaaa gauaacgggg gcugucagca agacugcguu aacacauucg     2220

gaagcuacga augucaaugc cgcagugggu ucgugcugca cgacaacaaa cacgacugca     2280

aagaagcagg augcgaccau aaagucacca gcacaagcgg aacgaucacu agccccaacu     2340

ggccggacaa auacccaucc aagaaagaau gcacaugggc caucuccagc acccccggcc     2400

accgcgucaa auuaacauuc auggagaugg acaucgaauc acaacccgaa ugcgccuacg     2460

accaccugga gguauucgac ggccgagacg ccaaagcacc agugcucggc cgcuucugcg     2520

gcuccaagaa accagaacca gugcuagcca ccggcagucg aauguuccuc cgcuucuaca     2580

gugacaacag uguacaacga aaaggauucc aagcaagcca cgcaacagaa ugcgguggcc     2640

aaguccgggc cgacgucaaa acaaaagacc uauacucaca ugcucaauuc ggugacaaca     2700

acuacccggg cgguguagac ugcgaauggg ucaucgucgc agaagaggga uacggggucg     2760

aacucguguu ccaaacauuc gaagucgagg aagagacaga uuguggcuac gacuacaugg     2820

aacucuucga cggguacgac agcaccgccc ccagacuagg ccgcuacugu ggaucagguc     2880

cacccgaaga agucuacagc gccggugacu caguacucgu gaaauuccac agcgacgaca     2940

caauuacaaa gaaaggcuuc caccuaagau acacguccac caaauuccag gacacccucc     3000

acagccgcaa augaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  3553
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt11)

<400>  3553
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucg       60

ccggcacccg uugccuccuu gcccuccucc uaccccaagu ccuacuaggc ggagcagccg      120

gccucguccc cgaacucggc cgccgcaaau ucgccgccgc cucauccgga cgccccuccu      180

cacaacccag cgacgaagua cucucagaau ucgaacuucg ucuacucucc auguucggcc      240

ucaaacaacg acccacuccc ucccgcgacg cagucguccc cccuuacaug cuagaccuuu      300

accgccgcca cuccggccaa cccggaucac ccgcccccga ccaucgccuc gaaagagccg      360

ccucccgagc caauaccguc cgcucauucc accacgaaga aucacucgaa gaacuacccg      420

aaaccagcgg aaaaacaaca cgcagauucu ucuucaaccu cuccagcauc cccaccgaag      480

aauucaucac cuccgccgaa cuacaaguau ucagagaaca aaugcaggac gcccucggca      540

acaacuccag cuuccaccac cgcaucaaca uauacgaaau aaucaaaccc gccacagcua      600

acuccaaguu ccccgucaca cgccuacucg acacccgccu agucaaccaa aaugccuccc      660

gcugggaauc cuucgacguc acccccgccg ucaugcgaug gaccgcacaa ggccacgcca      720

aucacggcuu cgucguagaa guugcacacc uagaagaaaa acaaggcguc uccaaacgcc      780

acguccgcau cuccagaucc cuacaccaag acgaacacuc auggucccaa auccgccccc      840

uccuagucac cuucggacau gacggcaaag gacacccgcu ccacaaacgc gaaaaacgcc      900

aagccaaaca caaacaacgc aaacgccuca aaucauccug caaacgccac ccacucuacg      960

uagacuucuc cgacguagga uggaacgacu ggauagucgc acccccaggc uaccacgcau     1020

ucuacugcca cggagaaugc ccauucccac uugccgacca ccucaacucc accaaccacg     1080

cuaucguaca aacacucguc aacuccguca acucaaaaau cccaaaagca ugcugcgucc     1140

ccacagaacu cucagccauc uccaugcucu accucgacga aaacgaaaag gucguccuaa     1200

aaaacuacca agacaugguc gucgaaggcu gcggcugccg cuagggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  3554
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt11)

<400>  3554
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauac       60

cgggcaaccg caugcucaug gucguucucc ugugccaagu ccuacucggc ggcgcaagcc      120

acgccucacu cauccccgaa acugggaaaa aaaaagucgc cgaaauccaa ggccacgccg      180

gcggaagacg cuccggccaa ucacacgaac uccuccgcga cuucgaagcc acccuacuac      240

aaauguucgg ccuccgccgc cgcccacaac ccucaaagag cgccgucauc cccgacuaca      300

ugcgcgaccu auaccgacuc caauccggcg aagaagaaga agaacaaauc cacuccaccg      360

gacucgaaua ccccgaacgc cccgccuccc gagcaaacac cguacguucu uuccaccacg      420

aagaacaccu cgaaaauauc cccggcaccu ccgaaaacuc cgcauuccgc uuccuauuca      480

accucuccuc cauccccgaa aacgaaguaa ucucauccgc agaacuccgc cuauuccgcg      540

aacaagucga ccaaggcccc gacugggaaa gaggcuucca ccgaauaaac auuuacgaag      600

ucaugaaacc cccagccgaa gucguacccg gccaccucau cacacgacuu cucgacacac      660

gccuagucca ccauaacgua acucgcuggg aaaccuucga cguaagcccc gccguccucc      720

gauggacccg ugaaaaacag cccaacuacg gccucgcaau ugaagucacc caccuccacc      780

aaacacgcac acaccaaggc caacaugucc gcauaucccg aucacuccca caaggcuccg      840

gcaacugggc ccaacuccgu ccacuccucg uuaccuucgg ccaugacgga cgcggucacg      900

cccucaccag acgccgcagg gccaaacgau cccccaaaca ucacucccag cgcgcucgua      960

aaaaaaacaa aaacugccgc cgccauuccc uauacguaga cuucuccgac gucggcugga     1020

acgacuggau agucgcaccc cccggauacc aagccuucua cugccacggc gacugccccu     1080

ucccacucgc agaccaccua aacucaacca aucacgccau cguacaaacc cucguaaacu     1140

cagucaacuc cuccauuccc aaagccugcu gcguacccac cgaacuaucc gccaucucca     1200

ugcucuaccu agacgaauac gacaaagucg uccucaaaaa cuaccaagaa auggucgucg     1260

aaggcugcgg cugccgauag ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  3555
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt11)

<400>  3555
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

ggcuaggccg acgagcacaa uggcuaugcu gguggugggg ccuacuaugc ucaugcugcg      120

gaccaccucc ccuacgccca ccccugcccg cagccgcugc cgcagcugcc ggcggccaac      180

uacuaggcga cggcggcuca cccggccgaa cagaacaacc cccucccucu ccccaauccu      240

cauccggauu ccuauaccgc agacucaaaa cccaagaaaa acgcgaaaug caaaaagaaa      300

uccuaucagu acucggccug ccacauagac ccagaccccu ccacggacuc caacaacccc      360

aaccucccgc ccugcgucaa caagaagaac aacaacaaca acagcaacua ccccgcggcg      420

aacccccacc cggccgccua aaaucagcac cccuauuuau gcucgaccuu uacaacgccc      480

ucucugccga caaugaugaa gacggcgccu ccgaagguga acgccaacaa uccuggcccc      540

acgaagccgc cucaucauca caacgacgac aacccccacc cggcgccgcc cacccacuca      600

accgaaaauc ccuucucgcc cccggaucug guuccggggg cgcuucccca cucaccuccg      660

cacaagacag cgccuuccua aacgacgccg acaugguuau gucauucgua aaccuagucg      720

aauacgacaa agaauuuuca cccagacaaa gacaccauaa agaguucaaa uucaaccucu      780

cccaaauccc agaaggcgaa gucguaacag ccgccgaguu ccgaaucuac aaagacugcg      840

ucaugggauc cuucaaaaac caaaccuucc uaauaagcau cuaccaagua cuacaagaac      900

accaacaccg ugacuccgac cucuuucuuc uagacacccg aguagucugg gccucagaag      960

aagguuggcu ugaguucgac aucaccgcca ccagcaaccu auggguaguc acaccccaac     1020

acaacauggg acugcaacua ucagucguaa cccgcgacgg cguacacguu cacccccgag     1080

cagccggacu cguaggucgc gacggacccu acgacaaaca acccuucaug gucgccuucu     1140

uuaaagucuc cgaaguacac guccgaacaa cacgauccgc aucaucccgc cgccgccagc     1200

aaucccggaa ccgaucaaca caaucccaag acgucgcccg cgucagcucg gcuucggacu     1260

acaacuccag cgaacuaaaa acagcaugcc gcaaacacga acuauacguc uccuuucaag     1320

accucggaug gcaagacugg aucaucgcac ccaaaggaua cgcagcaaac uacugcgacg     1380

gagaaugcuc cuucccccua aaugcacaca ugaacgcaac caaccacgcc aucguccaaa     1440

cccucgucca ccuaaugaac cccgaauaug uacccaaacc cugcugcgcc ccaaccaaac     1500

uaaacgcaau cucaguacuc uacuucgacg acaacuccaa cguaauccuc aagaaauacc     1560

gcaacauggu uguccgugcc ugcggaugcc acuaaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  3556
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt11)

<400>  3556
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

uccgaucacu acgcgccgca gccccacacu ccuucguagc acucugggca ccccuauucu      120

uacuccgcuc cgcacuagcc gacuucuccc ucgacaacga aguccacucg agcuucaucc      180

accgccgccu acggucccaa gaaagacgcg aaaugcaacg cgaaauccuc ucaauucuag      240

gacuccccca ccgcccccgc ccccaccucc aaggcaaaca caacucugcc cccauguuca      300

ugcucgaccu cuacaacgcc auggcaguag aagaaggagg cggacccggc ggccaaggcu      360

ucucauaccc cuacaaagcc guuuucucaa cccaaggccc gccccucgca ucccuccaag      420

acucacacuu ccuaaccgac gccgacaugg uaaugucauu cgucaaccuc guagaacaug      480

acaaagaauu cuuccacccc cgcuaucacc accgcgaauu ccgauucgac cucucgaaaa      540

uacccgaagg cgaagccgug accgcagccg aauuccgcau auacaaagac uacauccgcg      600

aacgcuucga caacgaaaca uuccgcaucu ccgucuacca agugcuccaa gaacaccucg      660

gccgcgaaag cgaccucuuc cuacuugacu cccgcacacu uugggccucu gaagaagguu      720

ggcucguauu cgacauaaca gccaccucaa accacugggu agucaacccc cgucacaacc      780

uaggacucca gcuaucagua gaaacacucg acggccagag caucaacccc aaacuugcgg      840

gacucaucgg ccgccacgga ccacaaaaca agcagcccuu cauggucgcc uucuuuaaag      900

ccaccgaagu acauuucaga uccauacgcu ccaccggguc caaacaacga ucacaaaacc      960

gauccaaaac cccaaaaaac caagaagcuc uacgaauggc aaacguagcu gaaaacagcu     1020

ccucagacca acgccaagcc ugcaaaaaac acgaacucua cgucuccuuc cgagaccucg     1080

gcuggcaaga cuggaucauc gccccagaag gcuacgcagc auacuacugc gaaggcgaau     1140

gcgccuuccc ccuuaacucu uacaugaacg ccaccaacca cgcaaucguc cagacccucg     1200

uacacuucau caaccccgaa acugucccca aacccugcug cgcccccacc caauuaaacg     1260

caaucuccgu ccucuacuuc gacgacuccu cgaacgucau acucaaaaaa uaccgaaaca     1320

uggucguccg cgccugcggc ugccauuaag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  3557
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt11)

<400>  3557
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaag       60

ccuccgccgc ccuccucugc cuccuccuca ccgccgccgc cuucuccccc caaggccuag      120

cccaacccgu cggcaucaac accuccacca ccugcugcua ccgauucauc aacaaaaaaa      180

uccccaaaca acgccucgaa uccuaccgcc gcaccaccuc cucacacugc ccccgcgaag      240

ccgucaucuu caaaaccaaa cucgacaaag aaaucugcgc cgaccccacc caaaaauggg      300

uccaagacuu caugaaacac cucgacaaaa aaacccaaac ccccaaacuc uaaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  3558
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt11)

<400>  3558
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugc       60

ucacgcugau caucuuauua ccggucguca guaaauuuag cuuuguauca cugagcgcac      120

cccaacacug gucaugccca gagggcacuu uggcagggaa cggcaauucg acgugcguag      180

gaccagcccc auuccugauc uucagccacg gaaauagcau cuuccgaauc gacacagaag      240

gaacgaacua ugagcaacuc guagucgacg cagggguauc gguuaucaug gacuuccauu      300

acaacgagaa aagaauauac ugggucgacc uagaacgaca gcuccugcaa aggguauucc      360

ugaacggcuc gcggcaggaa cggguaugca acauagagaa aaacgucagc ggcauggcca      420

uaaacuggau caacgaagaa gugaucuggu ccaaccaaca ggaaggcauc auaaccguca      480

cugacaugaa aggaaacaac agccacaucc uccuaucagc gcuaaaguac cccgccaaug      540

ucgcggucga cccaguagaa cgguucauuu ucugguccuc cgaaguagcu gggagccuuu      600

accgcgcaga ccuagacggc gucggaguaa aagcacuacu ugaaacaucc gagaaaauaa      660

cagcaguauc ccuugacguc cuagacaagc gccucuucug gauacaauac aaucgcgaag      720

ggucuaacag ccucaucugc aguugugacu augacggcgg gagcguacac aucucaaaac      780

acccaacaca acauaaucua uucgcgauga gccucuucgg ugacagaaua uucuacucaa      840

ccuggaagau gaaaacaaua uggauagcca acaaacacac aggcaaagac augguccgca      900

ucaaccucca cagcuccuuc guaccccucg gcgaacuaaa aguagugcac ccccuagccc      960

agcccaaagc cgaagaugau acgugggaac ccgaacaaaa gcugugcaaa cugcgcaaag     1020

ggaacugcag caguaccguu ugcggucaag acuuacaguc ucaccucugc augugcgcug     1080

agggguacgc ccuuucgaga gacagaaaau acugcgagga cgucaacgaa ugcgccuuuu     1140

ggaaccacgg cugcacacuu ggcugcaaaa auacaccggg aagcuacuac ugcacauguc     1200

ccguaggauu cguccuucua cccgauggaa agcgcugcca ccaacugguc ucguguccuc     1260

gcaacgucuc ggaaugcagc caugacugcg uacuaaccuc cgaaggucca cuaugcuucu     1320

gcccagaggg uucaguucua gagcgggacg gcaagacaug caguggaugc ucauccccag     1380

acaacggcgg augcucccaa cuaugcgucc cacugagccc ggucucaugg gaaugcgacu     1440

gcuucccugg guacgaccuc cagcuugaug aaaaaucaug cgcugccucc gggccccagc     1500

ccuuccuacu cuucgccaac ucgcaagaca uaagacauau gcacuucgac ggcacagauu     1560

acgggacccu gcugucccaa cagaugggca ugguauacgc acucgaccac gacccagugg     1620

aaaauaaaau cuauuucgcc cacacagccc uuaaguggau cgaacgcgcc aacauggacg     1680

gcagccaaag agaacggcuc auagaagagg ggguggacgu gccagagggc cucgcugucg     1740

acuggauagg gcgccgguuc uacuggacag accggggcaa aagccucaua ggcagaucag     1800

accucaacgg gaaaaggagc aagaucauaa cgaaagagaa uaucucgcaa ccccgcggaa     1860

ucgccgucca cccaauggca aaaagacuau ucuggacaga uacgggaaua aacccccgga     1920

ucgagagcuc cucccuacaa gggcucgggc gguuaguaau cgccuccagc gaccuaauau     1980

ggcccagcgg gauuaccauc gacuuccuaa cagacaaacu cuacuggugc gacgcaaaac     2040

aauccgucau cgaaauggcc aaucuagacg guagcaaacg acgccgacuc acacaaaacg     2100

acguaggcca ucccuuugcg gucgccgucu ucgaggacua cgucugguuc ucugauuggg     2160

ccaugcccuc agucaugcga gucaacaagc gcacgggaaa ggaucgagug aggcuccagg     2220

gcucgauguu gaaaccaagc agccuaguag ucguccaccc acuggcaaaa ccaggcgcag     2280

acccaugccu auaccagaac gggggcugug agcacaucug uaaaaagaga cuaggaaccg     2340

cauggugcuc augcagggaa ggguucauga aagcguccga cggcaaaacc ugccuugccu     2400

uagacggaca ccaacuccua gcaggaggcg aaguugaccu uaaaaaccaa guaacgccgu     2460

uagauauccu cagcaaaaca aggguaagcg aggauaacau caccgaguca cagcacaugc     2520

ucguggcaga aauuauggug ucagaccaag acgacugcgc acccguaggc ugcucuaugu     2580

acgcaagaug cauauccgaa ggcgaagacg ccacaugcca gugccugaag ggcuuugccg     2640

gggacgguaa acugugcucc gacauagaug agugcgaaau gggaguaccc gucuguccgc     2700

ccgcaagcuc caaaugcaua aacacagaag gcggauacgu gugccggugc ucagaaggau     2760

accaaggcga cggaauccac ugccuggaca ucgacgaaug ccaguuaggu gaacauucgu     2820

gcggggaaaa cgccuccugc acuaacaccg aaggaggcua cacaugcaug ugcgccggac     2880

gucugagcga acccgggcua auaugccccg acuccacacc acccccacac uugcgcgagg     2940

acgaccacca uuacagcgua cggaacagcg acagcgaaug cccccuauca cacgacggcu     3000

acugcuuaca cgacggcguc ugcauguaca ucgaagcccu agacaaauac gcgugcaacu     3060

gcgugguagg uuacauaggu gagcguugcc aauaccgaga ccuuaaaugg ugggaacuac     3120

gccacgccgg acacggccaa cagcagaagg ucaucgucgu cgcaguaugc gucguagucc     3180

ucgucaugcu ucuacuccua ucacuauggg gcgcacacua cuacagaacu caaaaauuau     3240

uaagcaagaa ccccaaaaau ccguacgagg aauccagcag agauguccgc agccggagac     3300

cggcggacac ggaggacggc auguccucgu gcccgcaacc cugguucguc gucaucaaag     3360

aacaccaaga ccugaagaac ggcggccaac ccguagcagg agaagacgga caagccgccg     3420

acggaagcau gcaaccgacc ucguggcgac aagaacccca gcuaugcggc augggcacug     3480

agcagggcug cuggauucca guaaguagug acaaagguag cugcccacag gucauggagc     3540

gauccuucca uaugccuucu uacggaacac aaacacuaga aggcggugua gaaaagccgc     3600

auucucuccu guccgcaaac ccgcucuggc aacaacgagc acuagaucca ccccaccaaa     3660

uggaacucac ccaauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  3559
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt11)

<400>  3559
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

ccggccgccg cauggaaaug cucugcgccg gccgcguccc cgcacuccuc cucugccucg      120

gcuuccaccu ccuucaagcc guccucucca ccaccgucau ccccuccugc auccccggcg      180

aauccuccga caacugcacc gcccuagucc aaaccgaaga caacccacgc gucgcccaag      240

ucuccaucac aaaaugcucc uccgacauga acggcuacug ccuccacggc caaugcaucu      300

accucgucga caugucccaa aacuacugcc gcugcgaagu cggcuacacc ggcguccgcu      360

gcgaacacuu cuuccucacc guccaccaac cccucuccaa agaauacguc gcccucaccg      420

ucauccucau cauccucuuc cucaucaccg ucgucggcuc caccuacuac uucugccgcu      480

gguacagaaa ccgcaaaucc aaagaaccca aaaaagaaua cgaacgcguc accuccggcg      540

accccgaacu cccccaaguc uaaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  3560
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt11)

<400>  3560
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

aaggcgaaau caccaccuuc accgcccuca ccgaaaaauu caaccucccc cccggcaacu      120

acaaaaaacc caaacuccuc uacugcucca acggcggcca cuuccuccgc auccuccccg      180

acggcaccgu cgacggcacc cgcgaccgcu cagaccaaca cauccaacuc caacucuccg      240

ccgaauccgu cggcgaagua uacauaaaau ccaccgaaac cggccaauac cucgccaugg      300

acaccgacgg ccuccucuac ggcucccaaa cccccaacga agaaugccuc uuccucgaac      360

gccucgaaga aaaccacuac aacaccuaca ucuccaaaaa acacgccgaa aaaaacuggu      420

ucguaggccu caaaaaaaac ggcuccugca aaagaggccc ccgcacccac uacggccaaa      480

aagccauccu cuuccuccca cuccccgucu caucagacua aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  3561
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt11)

<400>  3561
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

ggguaggggg aggggacgug gaggacguaa cgccgaggcc gggagggugu cagauaagcg      120

ggagaggggc gagagggugc aacggaauac cgggagcggc ggcgugggag gcggcgcugc      180

cgaggaggag gccgaggagg cacccgagcg uaaacccaag aagcagagca gcagggagcc      240

cgaggacgag ggggagaagg acggaggaga ggccgagugg gagcaggcug ggggaucggg      300

ggagggggag agcacugccg ggagggcgac uagggggaag agggaggggg agggcgccgg      360

agaggguggg agggaggggg agggggaggg ggacggcggc gccgagagcg gcgccggcgg      420

cgagggggag caggccggga ccggcgggga cgauggcagc ggggagcaua accacguugc      480

cggcgcugcc ggaagaugga gggagugggg cguucccacc ggggcacuuc aaggauccga      540

agagacugua uuguaagaau ggaggguucu uucuaaggau acauccggau gggagagugg      600

auggggugag ggaaaagagu gacccgcaca uaaagcugca guugcaggcg gaggagagag      660

ggguaguaag cauaaagggg gugugcgcaa auagguaucu ggcgaugaag gaggauggga      720

ggcuauuggc gagcaagugu gugacggacg agugcuuuuu cuuugaaagg cuagagagca      780

auaacuacaa cacguacagg agcagaaagu auacgagcug guauguggcg cugaagagaa      840

cgggacagua caaguuaggg agcaagacag ggccagggca gaaggcaaua uuguuccugc      900

caaugagugc aaagagcuag ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  3562
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt11)

<400>  3562
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aauggauccu caccuggauc cuccccaccc uccucuaccg cuccugcuuc cacaucaucu      120

gccucgucgg caccaucucc cucgccugca acgacaugac ccccgaacaa auggccacaa      180

acgucaacug cuccuccccc gaacgccaca cccgcuccua cgacuacaug gaaggcggcg      240

acauccgcgu ccgccgacuc uucugccgca cccaauggua ccuacgcauc gacaaacgcg      300

gcaaaguaaa aggcacccaa gaaaugaaaa acaacuacaa caucauggaa auccgcacag      360

ucgccgucgg cauagucgca aucaaaggcg ucgaauccga auucuaccuc gccaugaaca      420

aagaaggcaa acucuacgcc aaaaaagaau gcaacgaaga cugcaacuuc aaagaacuca      480

uccucgaaaa ccacuacaac accuacgccu ccgccaaaug gacccacaac ggcggcgaaa      540

uguucgucgc ccucaaccaa aaaggcaucc ccguccgcgg caaaaaaacc aaaaaagaac      600

aaaaaaccgc ccacuuccuc cccauggcca ucaccuaagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  3563
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt11)

<400>  3563
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaac       60

uccuccccuc cguaguccuc aaacuauucc ucgcagccgu ccuauccgcc cucgucaccg      120

gcgaaucacu cgaacgccuc cgccgcggcc ucgccgcagg cacaagcaac cccgaccccc      180

ccaccgucuc caccgaccaa cuccuccccc uaggcggcgg ccgagaccgc aaaguccgcg      240

accuccaaga agcagaccuc gaccuccucc gcgucacccu cuccuccaaa ccccaagccc      300

uagcaacccc caacaaagaa gaacacggca aacgaaaaaa aaaaggcaaa ggacuaggca      360

aaaaacgcga ccccugccuc cgcaaauaca aagacuucug cauccacggc gaaugcaaau      420

acgucaaaga acuacgcgcc cccuccugca uaugccaccc cggcuaccac ggcgaacgau      480

gccacggccu aucccucccc guagaaaacc gacuauacac cuacgaccac accaccaucc      540

ucgccgucgu cgccgucguc cucucauccg ucugccuacu cguaaucgua ggacuccuca      600

uguuccgcua ccaccgccga ggcggcuacg acgucgaaaa cgaagaaaaa gucaaacucg      660

gcaugaccaa cucccacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  3564
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt11)

<400>  3564
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ucacuaaacu acuccccgcc cuccuacugc aacacguucu ccuccaccua uuacugcucc      120

ccauugcaau cccauacgcc gaaggccagc gaaaacgccg caacacgauc cacgaauuua      180

agaaaagcgc aaaaacaacc cuaaucaaaa uagacccugc acuaaaaaua aaaaccaaga      240

aagucaacac agcagaccaa ugcgcuaaca gaugcacccg gaacaaaggc cugccguuca      300

caugcaaggc auucgucuuc gacaaggccc gcaaacaaug ccugugguuc ccauucaacu      360

caaugagcuc aggcgucaag aaagaguucg gacacgaguu cgaccucuac gaaaacaaag      420

acuacauccg caacuguauc aucggaaaag gaagauccua caaaggcaca guaucaauca      480

ccaaguccgg caucaaaugc caacccugga gcagcaugau cccccacgaa cacuccuucc      540

uccccagcuc guaccgcggc aaagaccucc aagaaaacua cugccggaac ccccgaggag      600

aagaaggcgg ucccuggugc uucaccucca accccgaagu ccgcuacgaa gucugcgaca      660

ucccccaaug cagcgaagua gaaugcauga ccugcaacgg cgaauccuac agaggccuaa      720

uggaucacac cgaauccggc aagauaugcc aacgcuggga ccaucaaacc ccacaccgcc      780

acaaguuccu acccgaacgc uaccccgaca aaggauucga cgacaacuac ugccgcaacc      840

cugacgggca accacgcccc uggugcuaca cccuagaccc acacacacga ugggaauacu      900

gcgccaucaa aaccugcgcc gauaacacaa ugaacgacac ugacguccca cuagaaacca      960

ccgaaugcau acaaggacaa ggcgaagguu acagaggaac cguaaacacu auauggaacg     1020

gcauaccuug ccaacgcugg gacucccaau acccacacga acacgacaug acucccgaaa     1080

acuucaaaug caaagaccuc cgcgaaaacu acugccgcaa ucccgauggg uccgaaaguc     1140

ccuggugcuu caccacagac ccaaacaucc gcgugggaua cugcucccaa auucccaacu     1200

gcgacauguc ucacggucaa gacugcuacc gaggcaacgg caagaacuac augggaaacc     1260

ugucacagac cagauccggu cuaaccugcu ccauguggga caaaaacaug gaagaccucc     1320

acaggcacau auucugggaa cccgacgccu ccaagcucaa ugaaaacuac ugcaggaacc     1380

ccgacgacga cgcccacggc cccugguguu acacaggaaa cccccucauu ccuugggacu     1440

acugcccaau aucacgcugc gaaggugaca cuacacccac aauagucaac cucgaccacc     1500

ccgucaucuc uugcgccaaa acaaaacaac ucaggguagu caacggaauc cccaccagga     1560

caaacauagg cuggaugguc ucccuacggu accgcaacaa acacaucugc ggaggcucac     1620

ugaucaaaga auccuggguc cucaccgcac gccaaugcuu ccccagcaga gaccucaaag     1680

acuacgaagc cugguuaggu auucacgacg uccacggcag aggggacgaa aaaugcaagc     1740

aaguccucaa cguaagccag cucgucuacg gacccgaagg aucggaccuc guacucauga     1800

aacuggcccg ccccgcagua cucgacgacu ucgucucaac gauugaccug ccaaacuacg     1860

gaugcacgau cccagaaaag acgucaugua gcgucuacgg uuggggcuac acgggccuca     1920

ucaacuacga cggccuccuc cgagucgcac accuuuauau caugggcaac gaaaaaugca     1980

gccagcacca ccgaggcaaa gucacacuua acgaauccga aaucugugca ggagccgaga     2040

aaauaggcuc aggacccugc gaaggcgacu acggcggacc ccuggucugc gaacaacaca     2100

aaaugcgcau gguccuuggc gucaucguac ccggacgagg cugcgccauc cccaaccgcc     2160

ccggcauauu cgucagaguu gcauacuaug caaaauggau ccauaaaauc auacuaacau     2220

acaaaguccc ccagucauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  3565
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt11)

<400>  3565
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcaa       60

aagcagcagc aauaggcauc gaccuaggaa ccaccuacuc augcgucgga gucuuccagc      120

acggcaaagu agaaauaauc gcuaacgacc aaggaaacag aaccacgccc ucguacgucg      180

ccuucaccga caccgaacga cugauagggg acgcagcaaa gaaccagguc gcacucaacc      240

cacaaaauac agucuucgac gcaaaaagac ucauaggcag aaaauucggc gaccccguag      300

ugcaaagcga caugaaacac uggccauucc aagugauaaa cgacggggac aaaccaaaag      360

uccaagucuc auacaaaggc gaaacaaagg cauucuaccc agaagaaauc uccagcaugg      420

ucuuaaccaa aaugaaagaa auagccgaag cauaccucgg uuacccagua acgaacgcag      480

ucauuacagu acccgcauac uucaacgaca gccaacggca agccacgaaa gacgcgggag      540

ucauagcagg gcucaacgua uuaagaauaa ucaacgaacc aacagcagca gccaucgcau      600

acggccugga ucgcacaggc aagggcgaaa gaaacguacu gaucuuugac cuaggcgggg      660

gcacguucga cguaagcauc cugaccauag acgacgggau uuucgagguc aaagcaacag      720

caggggacac acaccugggc ggggaagacu ucgacaacag acucgugaac cacuucguag      780

aagaguucaa acgcaaacac aagaaagaca ucucgcagaa caaaagagca gugagaagac      840

uacggaccgc gugcgagcgc gcaaaacgca cccuaagcuc aagcacgcag gcgagccugg      900

aaauagacag ccucuucgaa ggaaucgacu ucuacacauc uauaacaaga gcgagauucg      960

aagaacugug cuccgaccuc uuccgcucca cgcuggagcc agucgaaaaa gcgcuccggg     1020

augcgaaacu ggacaaagca caaauccaug accucguacu ggucggaggc ucgacccgca     1080

uuccaaaagu gcaaaaacuc cuccaggacu ucuucaacgg acgagaccuc aacaaaucaa     1140

ucaaccccga cgaagcaguc gcguacgggg ccgcugucca agccgcaauc cugauggggg     1200

acaaaagcga gaaugugcaa gaccuccucc uccucgacgu ggccccacuc ucgcuuggac     1260

ucgagaccgc gggaggcgua augacagcac ucauaaaaag aaauucaaca aucccaacaa     1320

agcagacaca gaucuucaca acguauagcg acaaucaacc gggcguacuc auacaaguau     1380

acgagggcga acgcgcaaug acgaaggaca acaaccuucu aggcagauuc gagcucucag     1440

gcauaccacc agccccacgc gggguaccgc aaauagaagu gacauucgac aucgacgcaa     1500

acggaaucuu aaacguaaca gcgaccgaua aaucaaccgg aaaggcgaac aaaaucacaa     1560

ucacaaacga caaaggacgc cuuucaaaag aagagaucga gagaauggua caggaggcag     1620

aaaaguacaa agcagaggac gagguccaac gcgaaagagu auccgccaaa aacgcccugg     1680

aaucauacgc auucaacaug aaguccgccg ucgaagacga aggucuaaag ggaaagauau     1740

ccgaagccga caaaaagaaa guacuagaua aaugccaaga agucaucagc uggcucgacg     1800

caaacaccuu ggccgaaaaa gacgaauuug aacacaaaag aaaagaacuu gaacaaguau     1860

gcaaucccau aaucucaggc cuguaccaag gcgcaggcgg gccagggccc gggggcuuug     1920

gggcacaagg ccccaaagga ggaagcggaa gcgggccgac aauagaggaa guagacuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3566
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt11)

<400>  3566
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcga       60

aagcagcagc aaucggaauc gaccucggua ccacauacag cugcguaggc guauuccaac      120

acgggaaagu agaaaucaua gcaaacgacc aagggaaccg gacaaccccc uccuacgucg      180

ccuucaccga cacagaacga cuuaucggcg acgcagccaa aaaccagguc gccuuaaacc      240

cccaaaacac cgucuucgac gcaaaaagac ucaucggaag aaaauucggg gaccccgugg      300

uacaaagcga caugaaacac uggcccuucc aaguaaucaa cgacggagau aagcccaagg      360

uccaaguauc guacaaaggc gagaccaaag ccuucuaccc agaagaaaua ucaagcaugg      420

uguuaaccaa gaugaaggaa aucgccgaag ccuaccucgg cuacccagug acaaacgccg      480

uaauaaccgu gcccgcguac uucaaugacu cccaacgcca agccacgaaa gacgccggcg      540

ucauagccgg acuaaacgua cuacgcauaa uaaaugaacc gacagcagcc gccaucgcau      600

acggacucga ccgcacaggc aaaggcgaaa gaaacguauu gauauucgac uuaggcggag      660

gcaccuucga cgucucgaua cuaaccauag acgacggaau auucgagguc aaggccaccg      720

ccggagacac acaccuaggc ggcgaagacu ucgauaaucg ucuagugaac cacuucguag      780

aagaguucaa gcgcaaacac aagaaagaca ucucccaaaa caaacgugca gugcgaaggc      840

uaagaaccgc augcgaacgc gcaaaaagaa cccucagcuc cagcacacaa gcgagccuag      900

aaauagacag ucucuucgaa ggcaucgauu ucuacaccuc gauaacuaga gcgcgcuucg      960

aagaauuaug cagcgacuua uuccgaucga cauuagaacc uguagaaaaa gcgcuccggg     1020

acgcgaaacu agacaaagcc caaauccacg acuugguccu gguagggggc ucuacaagga     1080

uaccgaaagu gcaaaagcua uuacaagacu ucuucaacgg acgcgaucuc aauaaaucca     1140

ucaaccccga cgaggcagua gcauacggcg ccgcggucca ggcagcgaua cucaugggag     1200

acaaaucaga aaacgugcaa gaccuccugc uccuugacgu agcaccacuc ucgcucggac     1260

uagaaacggc gggagggguc augaccgcac ucaucaagag aaacaguacc aucccaacca     1320

aacaaaccca aaucuucacc acauacucag acaaccaacc gggagugcua auccaaguau     1380

acgaaggcga acgcgcgaug accaaagaca auaaccugcu aggaagauuc gaacuaucag     1440

gcauaccccc ggcuccacga ggcguccccc aaaucgaagu aaccuucgac auagacgcca     1500

acggaauccu caacgugaca gcgaccgaca aaagcaccgg gaaagcaaac aaaaucacaa     1560

ucacaaacga caaaggacga uuaagcaaag aagagaucga gcgaaugguc caagaagccg     1620

aaaaguacaa agccgaagac gagguccaac gcgaacgagu aagcgccaaa aacgcauuag     1680

aauccuacgc guucaauaug aaaagcgcag uagaagacga aggacugaaa gggaaaauaa     1740

gcgaagcaga caaaaagaaa guacucgaca aaugccaaga aguaaucucc uggcuagacg     1800

caaauacccu cgccgaaaaa gacgaguucg aacacaaaag aaaagaacug gaacaagugu     1860

gcaacccaau uaucucagga cuauaccagg gggcaggcgg gccaggaccc ggaggauucg     1920

gcgcgcaagg accaaaagga ggcagcggaa gcggaccaac aaucgaggaa guagacuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3567
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt11)

<400>  3567
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcga       60

cagcaaaggg cauagcaaua ggcaucgacc ucggcaccac auacuccugc guaggcgucu      120

uccaacacgg caaaguagaa aucaucgcaa acgaccaagg aaacaggaca acacccucau      180

acgucgcauu uaccgacacc gaaagacuua ucggagacgc ggccaaaaac caggucgcaa      240

ugaaccccca aaauaccguc uucgacgcaa agcgacucau aggacgcaaa uucaaugacc      300

ccgugguaca ggcagacaug aaacuauggc cguuccaagu uauaaacgaa ggcggaaagc      360

cgaaaguccu cguauccuac aaaggcgaaa acaaagccuu cuaccccgag gaaaucucga      420

gcaugguccu aaccaaacuc aaagaaacag ccgaagcauu ccucgggcac ccagucacca      480

acgcggucau aaccguacca gcauacuuca acgacucgca aagacaggca accaaagacg      540

ccggagucau cgcaggacug aacguccucc gaaucaucaa cgaaccaacc gccgcagcca      600

ucgccuacgg acuagacaaa ggcgggcaag gcgaacggca cguacuuauc uucgaccucg      660

ggggcggaac cuucgacguc uccauccuga ccaucgacga ugggauauuc gaagucaaag      720

ccacggccgg agacacacac cucggaggcg aagacuucga caaccgccua guaagucacu      780

ucgucgaaga guucaaacga aaacacaaaa aggacaucag ccagaacaaa cgagcaguac      840

gccgccucag gacagcaugc gaacgcgcca aaaggacacu aagcuccucc acgcaagcaa      900

accucgaaau agacagccua uacgaaggaa uagacuucua cacaagcauc acaagggcca      960

gauucgaaga acucugcgca gaccuauucc ggggcacacu cgaaccaguc gaaaaagcgc     1020

ugcgagacgc caagauggac aaagccaaaa uccaugacau aguccucguc ggaggcucca     1080

cccgaauccc caaaguacaa cgacuucuac aggauuacuu caacggaaga gaucucaaua     1140

aaucaaucaa ccccgacgag gcggucgcau acggcgccgc cgugcaggcc gcaauacuca     1200

ugggggacaa aagcgagaaa guacaagacc uguuacuacu ggauguggca ccccuaagcc     1260

ucgggcugga aaccgccgga ggggucauga ccgcccucau caaacgaaac uccacgaucc     1320

ccacaaaaca aacccaaaua uucaccaccu acuccgacaa ccagccagga guacuaaucc     1380

aaguauacga aggagaacgc gccaugacaa aagacaacaa ccuacuaggc cgguucgauc     1440

uaacaggcau accaccggcg ccccgagggg uaccccaaau cgaaguaaca uucgacaucg     1500

acgccaacgg cauacugaac gugaccgcaa cggacaaauc gaccgggaaa gugaacaaaa     1560

uaacaaucac aaacgacaag ggccgcuuaa gcaaggaaga aaucgagcgc augguccuag     1620

acgcagaaaa auacaaagcc gaagacgaag uacaacgaga gaaaaucgcc gcgaagaacg     1680

cgcuggaaag cuacgcauuc aacaugaaaa gcguaguauc agacgaggga cuaaaaggca     1740

aaauaagcga aagcgacaaa aacaaaauac ucgacaaaug caacgaacua cuaagcuggc     1800

uagaagucaa ucaacucgcc gaaaaagaug aguucgacca caaacgcaag gaacucgaac     1860

aaaugugcaa cccaauaauc accaaacuuu accaaggagg cugcacaggc ccagcaugcg     1920

gaacaggcua cguaccaggc cgaccugcca ccggccccac cauagaagaa guagacuagg     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3568
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt11)

<400>  3568
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagug       60

cgcgcggacc cgcaaucgga auagaccucg gcaccaccua cucaugcgug ggcguauucc      120

agcacggaaa agucgaaaua aucgcaaacg accaagggaa cagaaccaca ccauccuaug      180

uggccuuuac ugacaccgaa cgccuaaucg gagacgcugc caagaaccag guagcaauga      240

accccacaaa cacaaucuuc gacgcaaaga ggcuaaucgg acgcaaguuc gaagacgcaa      300

caguccaaag cgacaugaag cacuggcccu uccgcguagu auccgaagga ggcaaaccca      360

agguccaagu cgaauacaaa ggcgagacaa agaccuuuuu cccagaagag aucucaagca      420

ugguacucac caaaaugaaa gaaauagcgg aggcauaucu uggaggaaag guccacagcg      480

cagugauaac aguccccgca uacuuuaacg acagccaaag acaagcaaca aaagacgcag      540

gaaccauaac aggacuuaac guccuccgaa uaaucaauga accaacagca gcagcaaucg      600

cauacggccu agacaagaaa ggcugcgccg gaggcgagaa aaacguccua auauucgacc      660

uaggcggggg aacguucgac gucucaauac ucaccauaga agacggcauc uucgagguca      720

aaagcacggc cggagacaca caccucggcg gggaagacuu cgacaaccgc auggugagcc      780

aucucgccga agaguucaaa agaaagcaca agaaagauau aggccccaac aaacgggcag      840

ugagaaggcu caggaccgca ugcgaacggg cgaaaagaac ccucagcuca agcacacaag      900

caaguauuga aaucgacucc cuauacgaag ggguagacuu cuacaccuca aucacacggg      960

cccgcuuuga ggaacuaaac gccgaucugu uccgcggaac acuagaacca gucgaaaaag     1020

cacuccgaga cgcaaaauua gacaaaggcc aaauucaaga aauaguccug gucggagguu     1080

ccacccgcau cccaaaaauc caaaaacuac uacaagacuu cuucaacggg aaagaacuca     1140

acaaaucaau uaaccccgau gaagcagucg ccuacggagc agcaguacaa gcagcgauac     1200

ucaucgggga caaaagcgag aacguccaag accuacuacu gcuagacgug accccacucu     1260

cacucgggau agagacagca ggcggaguaa ugaccccacu gauaaaacga aacacaacca     1320

uacccacaaa acagacccag accuucacaa ccuacagcga caaccaguca uccguacucg     1380

uccaggugua cgagggagaa cgagcaauga cgaaagacaa caaccuauug ggcaaguucg     1440

accuaacggg cauaccgccc gcgccccgcg guguaccaca aaucgaaguc acuuuugaca     1500

uagacgccaa cggaauccua aacgugaccg cggccgacaa aagcacaggg aaggaaaaca     1560

agaucacaau aacaaacgac aaagggagac ugagcaaaga cgacauugac cgaauggucc     1620

aagaagcaga acgcuacaaa ucugaagaug aggcaaacag agaccgaguc gcugcaaaga     1680

acgcacugga aucuuacacc uacaacauca agcagaccgu cgaagacgaa aaacugcgag     1740

gaaaaauaag cgaacaagac aaaaacaaaa uacuggacaa augucaagaa gucauaaacu     1800

ggcucgaccg aaaccaaaug gccgaaaaag acgaauacga acacaaacaa aaagaacucg     1860

aacgaguaug caaccccaua aucucaaaau uauaccaagg aggcccagga ggcgggagcg     1920

gcggaggagg cuccggagcg agcggaggcc ccaccaucga agaaguagau uaaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  3569
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt11)

<400>  3569
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucgg       60

ucguaggaau cgaucugggc uuucaaucau gcuacguugc aguggcgaga gcaggaggaa      120

ucgaaaccau agccaacgaa uacagcgaua gguguacgcc ggcaugcauc agcuucggcc      180

ccaaaaacag aucaauagga gcagccgcca aaucacaagu caucuccaac gcaaagaaca      240

ccguacaagg cuucaagcga uuccauggca gagccuuuuc ggacccguuc gucgaagcug      300

aaaaauccaa cuuagcguac gacauaguuc aacucccaac aggauuaacc ggcaucaaag      360

ucaccuacau ggaagaggag cgaaacuuua ccaccgaaca gguaaccgcg augcuccuaa      420

gcaagcuaaa ggaaaccgca gaaagcgucc ucaaaaagcc cgucguagau ugcguggucu      480

ccgucccaug cuucuacacg gacgcagaac gucgcagcgu aauggacgcc acacaaauag      540

ccggacucaa cugccuacgg cugaugaacg aaacgaccgc agucgcacug gccuacggga      600

uauauaagca agaccuacca gcgcuggaag aaaaaccacg uaacgugguc uucgucgaca      660

ugggacacuc cgccuaccaa gucuccgugu gcgcguucaa ccgcggcaaa cucaaagucc      720

ucgcaacagc guucgauacc acauugggcg gacgcaaguu cgaugaagua cucguaaacc      780

acuucugcga ggaguucggc aaaaaguaca aacucgacau caaaucgaaa auacgagcac      840

uacuccgccu uagccaagaa ugugaaaaac uaaagaaacu gaugucagca aacgccagcg      900

accuaccacu aucaauagaa ugcuucauga acgacguaga cguaagcgga acgaugaauc      960

gcggaaaauu ccuggaaaug ugcaacgacc uccucgcccg aguugagccg ccacuacgga     1020

gcgugcucga acaaaccaag cucaagaaag aagacauaua cgccguagaa auagucgggg     1080

gcgcaacccg cauccccgcc gugaaagaga aaaucucaaa auucuucggg aaagaacuca     1140

gcaccacacu caacgccgac gaagcgguga cccgaggcug cgcgcuccaa ugcgcaaucc     1200

uaagccccgc cuucaaagua cgagaguucu ccauaaccga cguagucccc uaucccauau     1260

cccuuaggug gaauagcccc gcagaagaag gcagcagcga cugcgaagua uucagcaaaa     1320

accacgccgc acccuucuca aaaguacuga ccuucuaccg aaaagaacca uucacacucg     1380

aggcauacua cagcucccca caggaccucc cauacccaga cccggccauc gcccaauuca     1440

gcguacaaaa agucacacca caaagcgacg guagcucgag caaagucaag guaaaagucc     1500

gggucaacgu ucacggcaua uucucaguaa gcagcgcaag ccucguagaa guacacaaau     1560

ccgaggaaaa cgaagaaccc auggaaaccg accaaaacgc caaagaagaa gagaaaaugc     1620

aaguagauca agaggaacca cacgucgagg aacaacagca acagaccccc gccgaaaaca     1680

aagcagaaag cgaagaaaug gaaaccagcc aagccggcuc caaagauaag aaaauggacc     1740

aaccaccaca agccaaaaag gccaaaguca aaacauccac agucgaucuc cccauagaaa     1800

accaacuacu auggcaaauc gaccgcgaga ugcucaacuu auacauagag aaugaaggca     1860

aaaugauaau gcaagacaaa cucgaaaaag agagaaacga cgccaaaaac gcagucgaag     1920

aauacgucua cgaaaugcga gacaaacuaa gcggcgaaua cgagaaauuc guaucggaag     1980

acgacagaaa cagcuucacc cuaaagcugg aggacaccga aaacuggcua uacgaagacg     2040

gagaagacca acccaaacaa guauacguag acaaacucgc agaacucaaa aaccuaggcc     2100

aacccaucaa aauacgauuc caagaauccg aggaacgccc caaauuauuc gaagaacucg     2160

gcaagcaaau ccaacaguac augaaaauaa uaucgagcuu caaaaacaaa gaagaccaau     2220

acgaucaccu ggacgcagca gacaugacua aaguagaaaa aucaacaaac gaagcaaugg     2280

aauggaugaa caacaaacuc aaccuucaaa acaagcaaag ccuuaccaug gacccaguag     2340

ucaaaagcaa ggaaaucgaa gccaagauca aagagcucac aucaaccugu uccccuauca     2400

uaucaaaacc caaaccaaaa guagaaccac ccaaggaaga acagaaaaac gccgaacaaa     2460

acggccccgu cgacggacaa ggcgacaacc ccggccccca agccgccgaa caagggaccg     2520

acaccgcagu accaagcgac agcgauaaga aacuucccga aauggacauc gacuagggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  3570
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt11)

<400>  3570
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucag       60

ucgucggcau cgaucucggg uuccugaacu gcuacauagc agucgcccgg aguggaggga      120

ucgagacaau agcaaacgaa uacucggacc gcugcacacc cgcaugcaua agccucggcu      180

ccagaacgag agccaucggu aacgccgcua agagccaaau cguaaccaac guacgcaaca      240

caauccacgg cuuuaagaaa cuccacggca gaucguuuga cgacccuaua guccagacag      300

agcgcauacg acugcccuac gaacuacaga aaaugccaaa cgggagcgcg ggcgucaaag      360

uccgauaccu agaagaggag cgcccauucg caauugaaca aguaacugga augcugcuag      420

caaaauuaaa agaaacgagc gaaaacgccc uaaagaaacc cguagccgau ugcguuaucu      480

caauaccgag cuuuuucaca gacgcagagc ggcgcucagu cauggccgca gcccaagucg      540

ccggccucaa cugccuccgc cucaugaacg aaacaacugc cguugcccug gccuacggca      600

ucuacaaaca agaccuaccg ccccuggacg agaaaccgcg aaacgucguc uuuaucgaca      660

ugggacacuc cgcauaccaa guucuaguau gcgccuucaa caaaggcaag cucaaaguac      720

uggcaaccac auucgacccc uaccucggug gacgaaacuu cgaugaagcg cucgucgacu      780

acuucugcga cgaguucaaa acgaaauaca aaaucaacgu caaggagaac ucccgggccc      840

ugcuaagacu cuaccaagag ugcgaaaaac uaaagaaacu uaugucggca aacgccucag      900

accugccccu caacauagaa uguuucauga augaccucga cguaagcucc aaaaugaacc      960

gcgcacaauu cgagcaacua ugcgccagcc ugcuagccag gguagaaccu ccacuaaaag     1020

cagucaugga gcaggcuaac cuacaacgcg aggacauaag cagcaucgag aucgugggag     1080

gcgccacacg cauacccgca gucaaagaac aaaucaccaa auuuuuccua aaagacaucu     1140

caaccacccu caacgccgac gaagcaguag cgcgcggcug cgcccuccaa ugcgcgauac     1200

ucagcccagc cuucaaggua cgcgaguuca guaucaccga ccucgucccc uacucaauaa     1260

cacuaagaug gaaaaccucg uucgaagacg gcuccggaga augcgaagua uucugcaaga     1320

aucacccggc accguucucg aagguaauca ccuuccacaa gaaagaaccc uucgaacuug     1380

aagcauucua cacaaaucuu cacgagguac cauacccgga cgcacgcaua ggcucauuca     1440

ccauccaaaa cgucuucccc caauccgacg gcgacucaag caaagugaaa gugaaagucc     1500

gcguaaauau ccacggaaua uucuccguag caagcgcauc aguaaucgag aaacaaaacc     1560

ucgaaggcga ccacagcgac gcaccaaugg agaccgaaac cagcuucaag aacgagaaca     1620

aggacaauau ggacaaaaug caaguagacc aggaagaagg acaccagaaa ugccacgcag     1680

aacacacccc cgaggaagaa aucgaccaca caggcgccaa aacaaaaucc gccguaagcg     1740

acaaacagga ucgccuaaac cagacgcuca aaaaggggaa agugaaaucc auagaccuac     1800

ccauccaguc cucacuuugc cgccagcuag gccaggaccu ucugaacuca uacaucgaaa     1860

acgaggggaa aaugaucaug caagacaaac ucgaaaagga aaggaaugac gccaaaaacg     1920

cagucgaaga auacguauac gacuuccgcg accgacuggg cacaguauac gaaaaauuca     1980

uuacacccga agaccucagu aagcuaagcg cggucuugga ggacaccgag aacuggcucu     2040

acgaagacgg cgaggaccag cccaaacaag uauacgugga caaacuacaa gaacucaaaa     2100

aguacggaca accuauccaa augaaguaca uggaacacga agaacgccca aaagcucuaa     2160

acgaccuagg caagaagaua cagcucguaa ugaaggucau cgaagccuac cgcaacaaag     2220

acgaaagaua cgaccaccua gacccaaccg aaauggaaaa aguagaaaaa ugcauaagcg     2280

augcaaugag cuggcucaac ucuaagauga augcacaaaa caaacucucc cuuacccaag     2340

acccagucgu aaaagucuca gaaauugucg cgaaaagcaa agagcuagac aacuucugca     2400

aucccaucau cuacaagccc aaacccaaag cagaaguacc cgaagacaaa cccaaagcca     2460

acuccgaaca caacggcccg auggacggcc aaagcggaac cgaaacaaag uccgacagua     2520

ccaaagacag cucgcagcac accaaguccu ccggcgaaau ggaagucgac uaaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  3571
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt11)

<400>  3571
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaac       60

uaagccuggu cgcagcaaug cugcuacuac uaagcgcagc aagggcagag gaagaagaca      120

agaaagagga cgucggcaca guagucggaa uagaccuggg gacgaccuac agcuguguag      180

gggucuucaa gaacggcaga guugaaauca ucgcaaacga ccaaggcaac cgaauaacac      240

cgagcuacgu agcguucaca cccgaaggcg aaagacucau cggggacgca gccaaaaacc      300

aacuaacaag caacccggaa aacacagugu ucgacgccaa aagacuaauc ggcagaaccu      360

ggaacgaccc cuccguccaa caagacauaa aauuccuccc auucaaagug guagaaaaga      420

aaacgaaacc cuacauacaa gucgacauag ggggcgggca gacaaaaaca uucgcgccag      480

aagaaaucag cgcaaugguc cuaaccaaaa ugaaagaaac ggcagaagcg uaccugggaa      540

agaaagucac ccacgccguc gucacggucc ccgccuacuu caacgacgcg caacgacaag      600

caaccaaaga cgcaggcacg aucgcgggac ugaacguaau gaggauaauc aacgaaccaa      660

cagcagccgc caucgcauac ggacuggaca agcgcgaagg agagaaaaac auacuggucu      720

ucgaccuggg cggaggaaca uucgacgucu cgcuacugac aauagacaac ggcguauucg      780

aggucguggc uacgaacgga gacacacacc uaggagggga agacuucgac caacgaguca      840

uggaacacuu cauaaaacua uacaagaaga aaaccggaaa agacguaaga aaagacaaca      900

gagccguaca aaaacugagg cgcgaaguag aaaaagcgaa acgggcccug agcucgcaac      960

accaagcgag aauagaaaua gaguccuucu acgaaggaga agacuucagc gaaacacuaa     1020

cgcgcgccaa auucgaagaa cucaacaugg accucuuccg cucaacuaug aagcccgucc     1080

aaaaagugcu cgaagacagc gaccugaaaa agagcgauau cgacgaaaua guacugguag     1140

gcggaagcac acggauccca aaaauacagc aacucgugaa agaguucuuc aacggaaaag     1200

aaccaucgcg agggaucaac ccagaugaag cggucgcaua cggugcagcg guccaggccg     1260

ggguacuaag cggagaccaa gacacaggag aucugguacu ccuugacgug ugcccacuaa     1320

cccucgggau agagaccgua ggcggcguua ugacaaaacu gaucccccgc aacaccguag     1380

uacccacgaa gaaaagccaa aucuucagca cggcaagcga caaccaaccg accguaacca     1440

uaaaagugua ugagggggaa cgaccccuca cgaaagacaa ccaccuacuc ggcacauucg     1500

accucacagg aauaccacca gccccgcgcg gaguaccaca aaucgaagua acguucgaaa     1560

ucgacgugaa cggaauccua cgcgucaccg ccgaggacaa agggaccggc aacaagaaca     1620

aaaucaccau cacgaacgac caaaaccgcc ucacaccgga ggaaaucgaa cguaugguca     1680

acgacgcgga aaaguucgcg gaagaggaca agaaacucaa agaacgcaua gacacgcgaa     1740

acgaacugga aucauacgca uacucacuga aaaaccaaau aggagacaag gaaaagcuag     1800

gaggcaagcu aucgagcgag gacaaagaaa caauggaaaa ggcagucgag gagaaaauag     1860

aauggcuaga aucccaccaa gacgcagaca uagaagacuu caaagcgaaa aagaaagagu     1920

uagaagaaau cguucaacca aucaucagca aacuauacgg uagcgcaggc ccaccgccua     1980

caggcgagga agauaccgca gaaaaagacg agcuguaggg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  3572
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt11)

<400>  3572
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

ccccacgaga gcuagcagua ggaauagacc ucggaacuac auacucaugc guaggcguau      120

uccaacaagg acgcguagaa auacucgcaa acgaccaagg caaccgcacc acgccaagcu      180

acgucgccuu uaccgacacc gagagacucg uaggcgacgc agccaaaucg caggccgccc      240

ucaaucccca caacaccguc uucgacgcga aaagacuaau cggccgaaaa uucgccgaua      300

ccacagucca aagcgacaug aaacacuggc ccuuucgcgu agugucagaa ggaggaaaac      360

caaaagucag ggucugcuac cgaggagaag acaaaaccuu cuacccagaa gagauaucga      420

guaugguacu auccaaaaug aaggaaaccg cagaagccua ccuaggacaa ccaguaaagc      480

acgccgucau aacaguacca gcguacuuca acgacagcca aagacaagcc accaaggacg      540

ccggggccau agccggacua aacguccucc gcauaaucaa cgaaccgacc gcugccgcga      600

ucgcauacgg ccucgaccgc aggggagcug gcgaaagaaa cguccucauc uucgaccucg      660

gagggggaac auucgacguc ucaguacuaa guauagacgc cggcguauuu gaaguaaaag      720

ccacagcagg cgacacccac cuaggaggag aagacuucga caaccgacuc gugaaccacu      780

ucauggaaga guuccgacgc aaacacggca aagaccucuc cggcaacaaa cgggccuuga      840

gacgacucag aacagccugc gaaagagcaa aaagaacacu cagcucaagc acacaagcga      900

cauuagaaau agacucccua uucgagggcg uagacuucua uaccucgauc acacgcgcaa      960

gauucgagga acugugcuca gaccucuuca gaucaacccu cgaaccgguc gagaaagcuc     1020

uaagagacgc caaacuagac aaagcacaaa uccacgacgu cgucuuagua ggcggaagca     1080

cccgaauacc aaaagugcaa aaacuccuac aagacuucuu caacggaaag gagcucaaca     1140

agucaauaaa ccccgacgaa gccgucgcau acggggccgc aguacaggcc gcagugcuca     1200

ugggcgauaa augcgagaaa guccaagacc uucuacuacu cgacguagcc ccacuuuccc     1260

uagggcucga aaccgcgggc gggguaauga ccacccucau ccaacgaaac gcaacaauac     1320

caacuaaaca aacccagacc uucacaacau acucagacaa ucaaccggga guauucauac     1380

aagucuacga aggcgaacga gccaugacaa aagacaacaa ccuucucggc agguuugaac     1440

ucagcggcau acccccagcc ccacgcggcg ucccacaaau agaagucacc uucgauauag     1500

acgccaacgg cauacucagc guaacggcaa ccgaccgcag caccggaaaa gcgaacaaga     1560

uaaccaucac aaacgacaaa gggcgccuaa gcaaagaaga ggucgagcgc augguccaug     1620

aagcagaaca guauaaagca gaggacgaag cccaacgaga cagaguagca gcgaaaaaca     1680

gucucgaggc acacguguuc cacgucaaag gcucacuaca agaagagagc cuacgagaca     1740

aaauccccga agaagacagg cggaaaaugc aagauaaaug ccgcgaagua cucgcuuggc     1800

ucgagcacaa ccaacuggcc gaaaaggagg aauacgaaca ccaaaaacga gaacucgagc     1860

agauaugccg acccauauuc ucccgccucu acggcggccc cggcgucccc ggaggaagca     1920

gcugcggcac gcaagccaga caaggagacc ccucaaccgg acccauaauc gaagaagugg     1980

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  3573
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt11)

<400>  3573
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

ccccccgcga acuagccgua ggcaucgacc ucggcacaac cuacagcugu gucggcguau      120

uccaacaagg cagaguagaa auccuagcca acgaccaagg caacagaacg accccaucau      180

acgucgcguu caccgacaca gaaaggcuag uaggagacgc agcaaaaucc caagcagccc      240

uaaacccgca caacacugua uucgacgcca aacgccuaau cggacgaaaa uucgcagaca      300

caaccgucca aucagacaug aaacacuggc cauuccaagu cgucuccgaa gguggaaaac      360

ccaaaguacg aguaugcuac cgaggggaag acaaaacauu cuacccagaa gaaauaagcu      420

caaugguacu aagcaaaaug aaagaaaccg cggaagccua ccuaggccaa ccaguaaaac      480

acgccguaau cacggucccg accuacuuca gcaacuccca gagacaggcc accaaagacg      540

caggagcaau cgcaggccua aaaguacucc caaucauaaa cgaagccaca gccgcagcaa      600

uagccuacgg ccuggaccga agaggagccg gcaaacgaaa cguacucaua uucgaccuag      660

gaggaggaac auucgacgua uccguacucu cgaucgacgc cggggucuuc gaaguaaaag      720

cuaccgccgg cgacacccac cuaggaggcg aagacuucga caaccgccua gucaaccacu      780

ucauggaaga auuccgcaga aaacacggca aagaccuaag cggaaacaaa cgagcccuca      840

gacgacuccg aacagccugc gaacgagcca aacgcacccc aucaagcagc acccaggcca      900

cacuagaaau cgacucccua uucgaaggcg uagacuucua caaaagcauc accagagcca      960

gauucgaaga acucugcagc gaccuauucc gaagcacccu agaacccgug gaaaaagccc     1020

uccgcgacgc caaacuagac aaagcacaaa uccacgacuu cguacuaggc ggcgggcucc     1080

acagccaccc acaaggcgca gaagucgccg caggccuacu ccaacgacaa ggcgcagaac     1140

aagaacacca gccauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  3574
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt11)

<400>  3574
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucaa       60

aaggacccgc agugggaauc gaccuaggca ccaccuacuc augcguaggc gucuuccaac      120

acggaaaagu cgagauaauc gccaacgacc aaggaaacag gacgacacca ucauauguag      180

ccuucaccga caccgagcgc cuaauaggag acgccgccaa aaaccagguc gcaaugaacc      240

caacgaacac cguauucgac gccaaacgac uaaucggccg ccgauucgac gaugcagucg      300

uccagagcga caugaaacac uggcccuuca ugguaguaaa cgacgccggc cgaccaaagg      360

uacaagucga auacaaaggc gaaaccaaau ccuucuaccc cgaagaggug uccagcaugg      420

uccucaccaa aaugaaagaa auagcagaag cguaccuggg gaaaacaguc accaacgcag      480

uagucaccgu ccccgcauac uucaacgaca gccagagaca agcaacaaaa gacgcaggca      540

ccaucgccgg gcuaaacguc cuacgcauaa ucaacgaacc cacagcagcu gcaaucgcau      600

acggucucga caagaaaguu ggugccgaac gcaacguccu aaucuucgac cucgggggcg      660

gcaccuucga cguaucaauc cucacaauag aagacggaau auucgaaguc aaaagcaccg      720

caggcgacac ccaccuaggc ggcgaggacu ucgacaacag aaugguaaac cacuucaucg      780

cagaguucaa acggaaacac aagaaagaca ucuccgaaaa caaacgcgca guacgacgcc      840

uacggacagc augcgaacgc gccaaacgca cccucuccuc cuccacccaa gcaagcauag      900

aaaucgacag ccuauacgaa ggaauagauu ucuacacauc caucacaagg gcgcgcuucg      960

aagaacuaaa cgcagaccuc uuccgaggua cccucgaccc agucgaaaaa gcauuaagag     1020

acgcaaaacu agacaaaagc caaauccacg acauaguccu ggugggcgga ucaacccgua     1080

ucccuaaaau ccaaaaacua cuacaggacu ucuucaacgg aaaagaacua aacaagucca     1140

ucaacccaga cgaagcugug gcauacggcg cggccguaca agccgccauc cuaagcggcg     1200

acaaaucgga aaacgugcag gaccugcuac uccuagacgu cacaccccuc ucacuaggca     1260

uagaaaccgc gggcggcgua augaccgucc uaauaaaacg aaacacaacc auaccaacca     1320

aacaaacgca aaccuucaca acauacagcg acaaccaacc agggguacuc auccaaguau     1380

acgaaggcga acgcgcaaug accaaagaca acaaccuccu aggcaaauuc gaacuuacag     1440

gaaucccacc cgcaccccga gggguacccc aaauagaagu aacauuugac auagacgcca     1500

acggcauccu aaaugucagc gccgucgaca aaagcaccgg aaaagaaaac aaaauaacga     1560

uaaccaacga caaaggccga cugagcaaag aagacaucga gcgaauggua caagaagccg     1620

aaaaauacaa agcagaggau gaaaaacagc gcgacaaagu aucaagcaaa aacagucugg     1680

aaagcuacgc cuucaacaug aaagcaacag uggaagacga aaaacuccaa ggcaagauca     1740

augacgaaga caagcagaaa auccucgaca aaugcaacga aaucaucaac uggcucgaca     1800

agaaccaaac agcagaaaag gaagaguucg aacaccaaca gaaagaacuc gaaaaagucu     1860

gcaaccccau aaucacaaaa cuguaccaau ccgcaggcgg aaugcccggc ggcaugcccg     1920

gaggauuccc aggcggcggg gcaccaccca guggcggagc cagcucagga ccgacaaucg     1980

aagaaguaga cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  3575
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt11)

<400>  3575
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauaa       60

gcgccucaag agcagcagcc gccagacugg uaggagccgc agcaucaagg ggcccgacag      120

cagccagaca ccaagacuca uggaacggcc uaagccauga agcauuccgc cucguaagcc      180

gacgcgacua cgcgagcgaa gcaauaaaag gagccguggu cggcauagac cuaggaacca      240

cgaacucgug cguggccgua auggagggaa aacaagcaaa aguacucgaa aacgccgaag      300

gggcaagaac aacgcccuca guaguagcgu ucacugcgga cggcgaaagg cuaguaggca      360

ugccagcaaa acgacaagcg gugacaaacc caaacaacac guucuacgca acaaaacgac      420

ucauaggacg acgauacgac gacccggaag uacaaaaaga caucaaaaac gucccguuca      480

aaauagugcg cgccaguaac ggagacgccu gggucgaagc ccacggcaaa cucuacagcc      540

caucccagau cggcgccuuc guccuaauga agaugaaaga gaccgccgaa aacuaccucg      600

gacacacagc uaaaaacgca gucaucacug ugccagcgua uuucaacgac agccaaaggc      660

aagccacgaa agacgccggg caaauaagug gacuaaacgu ccuaaggguc aucaacgaac      720

cgacugcagc ggcccuggca uacggccuag acaagagcga agacaaagua auagccguau      780

acgaccuagg aggcgggaca uucgacauaa gcauccuaga aauacagaaa ggaguauucg      840

agguaaaaag cacgaauggg gacacguucc uggguggcga agacuucgac caagcacugc      900

uacgccacau cgugaaggag uucaaacgag aaacaggggu cgaccucaca aaagacaaca      960

uggcgcucca acgaguccgc gaagcagcgg aaaaagcaaa augcgaacua agcagcagcg     1020

uacaaaccga cauaaaccua cccuaccuaa caauggacag uagcgggcca aaacaucuca     1080

acaugaaauu aacaagagcu caauucgaag gcaucguaac ggaccuaaua cgacgaacca     1140

ucgccccgug ccaaaaagcc augcaagacg cagaaguaag caagagcgac auaggagaag     1200

uaauacuggu aggcggcaug acaagaaugc cgaaaguaca acaaaccgua caagaccuau     1260

ucggacgagc accaagcaaa gccgucaacc cggaugaagc aguggccauu ggcgcagcaa     1320

uccagggagg cgugcuagcg ggcgauguaa cagacguacu ccuacuagac guaaccccgc     1380

uaagccuagg aauagaaacc cuaggcggag uauucacaaa gcugauaaac agaaacacaa     1440

caaucccaac caagaaaagc caaguauuca gcaccgcggc agacgggcaa acccaagugg     1500

agaucaaagu cugucaagga gaacgagaga uggccggcga uaacaaacug cucggccaau     1560

ucacccugau cggcauacca cccgcgccga gaggaguacc ccaaaucgag gucacguucg     1620

auaucgacgc caacggcaua guccauguaa gcgccaaaga caaaggaacc ggacgcgaac     1680

aacaaauagu cauccaauca agcggaggcc uaagcaaaga cgacaucgag aacaugguca     1740

aaaacgcgga aaaauacgca gaggaagacc gaagaaagaa agaaagaguc gaagcaguaa     1800

acauggccga aggaauaaua cacgacaccg aaaccaaaau ggaagaguuc aaagaccaac     1860

uaccagcuga cgaaugcaac aaacucaaag aagaaauaag uaaaaugcga gagcuacuag     1920

cgcgcaaaga cagcgaaacg ggagaaaaua uacgccaggc agcgagcagc cugcaacaag     1980

cuagccuaaa acuguucgaa auggccuaca agaaaauggc auccgaaagg gaaggaagcg     2040

gaagcagcgg caccggcgaa cagaaagaag accaaaaaga agagaaacag uaaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  3576
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt11)

<400>  3576
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

auaaagaagc aggcggaucc gacgggccac gagaaaccgc cccaacaucc gcauacagcu      120

cgccagcccg aucacuagga gacaccggua uaacgccccu uucccccucc cacaucguca      180

acgacaccga cucaaacgua uccgaacaac aauccuucuu aguugucgug gccgucgacu      240

ucggaacaac aucauccggc uaugccuauu cauucaccaa agaaccggag ugcauccacg      300

ucaugcgucg cugggaagga ggagaccccg ggguuucaaa ccagaaaacc cccaccacca      360

uccuucucac ccccgaacgg aaauuccacu ccuucggcua cgccgcccgg gacuucuacc      420

acgaucuaga cccgaacgaa gcaaagcaau ggcucuaccu agaaaaauuc aaaaugaaac      480

uucacaccac cggcgaccuc acaauggaua cagaccuuac agccgcaaac ggcaagaaag      540

ucaaagcgcu cgaaaucuuc gccuacgcac uccaauacuu caaagaacaa gcccucaaag      600

agcuauccga ccaagccggc ucagaguucg aaaacucaga cguccgcugg gucauaacag      660

uaccugcgau auggaaacaa cccgccaaac aguuuaugag acaagcagcc uaccaggcug      720

gacuggcauc cccugaaaac ucagaacaac ucauaaucgc gcuagaaccc gaagcugcaa      780

gcauauacug ccgaaaacuc cgccuccacc agaugaucga acugagcucc aaagcagccg      840

uaaacggaua cagcggcucc gacacugucg gcgcaggauu cacccaagcu aaagaacaca      900

uccgacgaaa ccgccaguca cgcacuuucc uagucgaaaa cgucauagga gaaaucugga      960

gcgaacuaga agaaggagac aaauacgucg uggucgauuc aggcggcggc accgucgacc     1020

uaacagucca ccaaaucagg cuaccagagg gccaccucaa agagcuauac aaagcaaccg     1080

gcggccccua cggaucccuc gguguagacu augaguucga gaaacugcuc uacaaaauau     1140

uuggcgagga cuuuaucgag caauucaaaa ucaaacgccc cgccgccugg gucgacuuga     1200

ugaucgccuu cgaaagccga aaacgcgccg ccgcccccga cagaacaaac ccacuaaaca     1260

ucaccuuacc cuucucguuc aucgacuacu acaagaaauu ucgcggccac uccgucgagc     1320

acgcccuacg aaaaagcaac gucgacuucg ucaaaugguc aucgcaagga augcuccgua     1380

ugucccccga cgccaugaau gcccuauuca aacccacaau agacuccauc aucgaacacc     1440

uccgcgaccu cuuucaaaag ccagaaguau caaccgucaa auuucucuuc cuagucggcg     1500

gcuucgcaga agcaccccua cuccaacaag ccguucaagc cgcuuucggc gaccaaugca     1560

gaaucauaau cccacaagac guaggacuca ccauucucaa aggcgccgua cuuuucggcc     1620

ucgacccagc cgucauuaaa gugcgaagau ccccucugac auacggcguc ggaguccuaa     1680

accgcuacgu cgaaggaaaa cacccacccg aaaaacuucu agucaaagac ggcacccgau     1740

ggugcaccga cguauucgau aaauucauau cagcagacca aagcgucgcc cucggcgagc     1800

uagucaaaag auccuacaca cccgccaaac caagccaacu cgucaucguu aucaacauau     1860

acuccagcga acacgacaac guaucguuca uaaccgaccc cgggguaaag aaaugcggca     1920

cccuccgccu cgaccuaaca ggcaccucag gcaccgccgu cccagcacgc agagaaauac     1980

aaacccucau gcaguucggu gacaccgaaa ucaaagccac cgccaucgac auagcaacca     2040

guaaaucggu caaaguaggc auagacuuuc uaaacuacua aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  3577
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt11)

<400>  3577
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcuag       60

ccgucccaga aaugggcuua caaggacuuu acaucggaag cuccccagaa cgaucacccg      120

uacccagccc acccggauca ccccgcaccc aggaaucaug cggaaucgcg ccccugacac      180

ccagccaaag cccaaaaccc gaaguacggg ccccgcaaca agccuccuuc agcguagucg      240

uggccauaga cuucggaacg accagcagug gcuacgcauu cucauucgca agcgauccag      300

aggccauaca caugaugcga aaaugggaag gcggcgaccc aggaguagca caccagaaaa      360

ccccaacaug ccuacuccua acccccgaag gcgccuucca cucauucggc uacacugcaa      420

gagauuacua ccacgaccuc gacccggaag aagcccgcga cuggcucuac uucgagaaau      480

ucaagaugaa aauccacagc gccacagacc uaacacugaa aacccaacuc gaggcgguga      540

acggcaagac aaugccagca cucgaaguau ucgcacacgc ccuccgauuc uuccgcgaac      600

acgcacuaca agaacuacgc gaacaaagcc ccagucugcc cgagaaggac accguccggu      660

ggguguuaac cguacccgca aucuggaaac aaccagcaaa acaauucaug cgcgaagccg      720

ccuacuuagc cggacuugua agcagagaga acgcagaaca acuccucaua gcccuggaac      780

ccgaagccgc cuccguauac ugccgaaaac uacgacuaca ccaacuacua gaccugucgg      840

gccgcgcccc cggcggcggc cgccuaggcg aaagacgaag cauagacucc uccuuccgcc      900

aagcccgaga acaacuaaga agauccagac acucacgaac cuuccuagua gaauccggag      960

ucggagaacu augggccgaa augcaagccg gcgaccgcua cguagucgcc gacugcggag     1020

ggggcacugu cgaccuuacc guacaccaac uagaacaacc acauggcacc cuaaaagaac     1080

uauacaaagc cucgggaggu cccuacgggg cugucggcgu agaccucgca uucgagcaac     1140

uccuaugccg caucuucgga gaagacuuca ucgcaacauu caaacgccaa aggcccgccg     1200

caugggucga ccucacuauc gccuucgaag cacgaaaacg aacagcagga ccccaucgcg     1260

caggcgcccu caacaucuca cuacccuuuu ccuucauaga cuuuuacaga aaacaaagag     1320

ggcacaacgu agagacagca cucagacgau ccagcgugaa cuucguaaaa uggucauccc     1380

aagggaugcu gcgaauguca ugcgaagcaa ugaacgagcu auuccaacca acaguaucag     1440

gcauaaucca acacaucgaa gcacugcucg cccgaccaga aguacaaggc guaaagcucc     1500

ucuuccuagu cggcggauuc gccgaaagcg caguccucca acaugccguc caagccgccc     1560

ugggcgcacg cggacuacga gucgucguac cacacgacgu cggacucacg auacucaaag     1620

gagccguacu auucggacaa gccccaggag uaguccgcgu ccgccguucg ccgcucaccu     1680

acggcgucgg cguccucaac agauucguac caggacgcca ucccccagaa aaacugcugg     1740

uccgcgacgg ccgcagaugg uguacagacg ucuucgaacg cuucguagca gccgagcaau     1800

ccgucgcgcu aggagaggaa guccgccguu cauacugucc cgccagaccc ggccaacgaa     1860

gaguacucau caaccuauac ugcugcgcag cagaagacgc acgcuucaua acugacccag     1920

gcguccggaa augcggcgcc cucucacuag aacucgaacc cgccgacugc ggacaggaca     1980

ccgcaggagc cccacccgga cgacgcgaaa uucgggccgc caugcaauuc ggcgacaccg     2040

aaaucaaggu gacagccgug gacgucagca cgaaccgcag cguuagagca agcauagacu     2100

uccucucaaa cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  3578
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt11)

<400>  3578
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

gcgaaaugac cauccucggc ucagccgucc uuacccuacu acuagcggga uaccuagccc      120

aacaauaccu uccacuaccc acccccaaag ucauagguau agaccucgga accaccuacu      180

gcuccgucgg cgucuucuuu cccggaaccg gaaaagucaa agucauccca gacgaaaacg      240

gacacaucuc uauccccucg auggucagcu ucacagacaa cgacguauac gucggcuacg      300

aauccgucga gcuagccgac agcaacccac aaaacacaau cuacgacgcc aaacgcuuca      360

ucggcaaaau cuucaccgcc gaagaacucg aagccgaaau cggacgcuac cccuucaaag      420

uacucaacaa aaacggcaug gucgaguucu caguaaccag caacgaaacc auaaccguau      480

cccccgaaua cgucggcuca cgcuuacuac uaaaacucaa agagauggca gaggcuuacc      540

ucggcaugcc ggucgccaac gcugucauaa gcguccccgc ggaguucgac cucaaacaac      600

gcaacuccac cauugaagca gcgaaccugg caggacuaaa aauccuccgg guaauaaacg      660

aacccacagc agcagccaug gccuacggac uccauaaagc cgacgucuuu cacguucuag      720

ucaucgacuu aggcggaggc acccucgacg ucucccuccu caacaaacag ggcggaaugu      780

uccuaacacg cgccauguca ggcaacaaca aacucggcgg ccaggacuuc aaccaacgcc      840

uacuucaaua ccucuacaaa cagaucuacc agaccuaugg auucguaccc ucucggaaag      900

aagaaaucca ccgccuccgc caagccguag aaaugguuaa acucaaccuc acccuacacc      960

agucagcgca acuauccguc cuccucacgg ucgaagaaca agaccgcaaa gaaccccacu     1020

caucagacac cgaacucccc aaagacaaac ucuccucagc cgacgaccac cgcgugaacu     1080

caggcuucgg ccgcggccua uccgacaaga aauccggcga aucucaagua cucuucgaga     1140

cagaaauaag ccgcaaacuc uucgacaccc uaaacgaaga ccucuuccag aaaauacucg     1200

uacccaucca acaaguccua aaagaaggcc accuugagaa aaccgaaauc gacgaagucg     1260

uucucgucgg cggcuccacc cgcauccccc guauucgaca agucauacaa gaauuuuucg     1320

gaaaagaucc caacacuagc gucgaccccg accuugcagu agucacaggg guagccaucc     1380

aagccggaau agacggcgga uccuggcccc uucaagucuc cgcacucgaa auccccaaca     1440

aacaccuuca gaaaaccaac uucaacuagg gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3579
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt11)

<400>  3579
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

ccaucggagu ccaccucggc ugcacauccg ccugcguggc cgucuacaaa gacggacgcg      120

caggcguagu cgccaacgac gccggagacc gcgucacccc cgccguaguc gccuacagcg      180

aaaacgagga aauagucgga cucgccgcca aacaaucccg aauacgcaac auauccaaca      240

caguaaugaa agucaaacaa auccucggac gaagcagcag cgacccacaa gcccaaaaau      300

acaucgccga auccaaaugc cuugucaucg agaaaaacgg aaaacuacga uacgaaaucg      360

acacagggga agaaaccaag uucgucaacc cagaggacgu cgcacgccuc aucuucagca      420

aaaugaagga gaccgcacau agcguacuag gguccgacgc caacgacguc guaauaaccg      480

ucccauuuga cuucggcgaa aaacaaaaga acgcacuagg cgaagccgcc cgcgccgcug      540

gcuucaacgu ccugcgacua auacacgaac caucagcagc acuacuagcc uacggcaucg      600

gacaagacuc accaacaggc aaaucaaaca uacucguauu caaacucgga ggcacuagcc      660

uaucacuauc cguaauggag gugaacagcg gcaucuaccg cguacucagu accaacacag      720

augacaacau aggcggcgcc cacuucacag aaacccuagc gcaauaccua gcgucggaau      780

uucaacgcag cuucaaacac gacgucagag gaaacgcccg cgcgaugaug aaacuaacca      840

acagcgcgga agucgcaaaa cacucccucu caacccucgg cuccgccaac ugcuuccucg      900

acucacucua cgaaggccag gacuucgacu gcaacgucuc aagagcccgc uucgaacucc      960

ugugcucccc acuauuuaac aaauguaucg aagcaauacg cggacuccua gaccaaaacg     1020

gcuucacagc cgacgacauc aacaaagucg uccucugcgg cggcagcucg cgcaucccca     1080

aacuccaaca acuaaucaaa gaccucuucc cagccgucga acuacucaac ucgaucccac     1140

ccgaugaagu uauucccauu ggagccgcca ucgaagccgg cauccuaauc ggcaaagaaa     1200

accuacuggu agaagacuca cuaaugaucg aaugcucagc ccgcgacauc cucgucaaag     1260

gagucgacga aagcggagcc ucccgauuca ccguacuauu cccuuccgga acgccgcucc     1320

cagcccgccg acaacacacc cuccaagccc ccggcuccau cuccuccguc ugccucgaac     1380

ucuacgaaag ugauggcaaa aacucagcca aagaagaaac caaauucgcg caaguaguac     1440

uacaagaccu cgacaagaaa gaaaacggac uacgcgacau ccuagccgua cucaccauga     1500

aacgcgacgg aucacuccac guaaccugca cagaccaaga aacaggcaaa ugcgaagcua     1560

ucuccauaga aaucgccuca ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  3580
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt11)

<400>  3580
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccg       60

ugguaggacu cgacgucggg agccaaagcu gcuacauagc gguagccagg gcaggcggga      120

uagagacgau cgccaacgag uucuccgauc gcugcacacc cagcgucauc agcuuugguu      180

cuaaaaacag gacuauagga guggccgcca aaaaccaaca aauaacccau gcaaacaaca      240

ccgucagcaa cuucaaacga uuccacggac gugccuucaa cgaccccuuu auacaaaaag      300

aaaaagaaaa ccuauccuac gaccuagucc cccucaagaa uggaggcgug ggcaucaaag      360

uuauguauau gggagaagaa caccuguucu caguagaaca gauaaccgcc augcuacuaa      420

caaaacugaa ggaaaccgca gagaacaguc ugaagaaacc ugucaccgac ugcguaaucu      480

ccguacccuc cuucuucacc gacgcagaac ggagauccgu acuagacgca gcccaaauag      540

uaggccuaaa cugccuccgc cugaugaacg auaugacggc cguagcacuc aacuauggga      600

uuuacaaaca agaccuccca agccucgacg aaaaaccccg cauaguaguc uucgucgaca      660

ugggacacuc agcauuccag guaagcgcau gcgccuucaa caaaggaaaa cucaaagucc      720

uaggcacggc uuucgacccc uuccuaggcg ggaaaaauuu cgacgagaaa cucgucgaac      780

acuucugcgc cgaguucaaa accaaauaca aacucgacgc aaagagcaaa auccgagccc      840

uccuacgccu auaccaggaa ugcgaaaagc uaaagaaacu gauguccucc aacuccaccg      900

accuaccccu aaacaucgaa uguuucauga acgacaagga cgucagcgga aagaugaaca      960

gaucccaguu cgaggagcuc ugcgccgagc uacuccaaaa gauagaaguc ccccucuaca     1020

gccuucucga acagacccac cucaaaguag aagacguuuc agccgucgaa aucgucggcg     1080

gagcaacacg cauccccgcg gucaaagaac gcaucgccaa auucuucggg aaggacauau     1140

ccaccacccu aaacgcagac gaagcagugg cacgcgggug ugcccuccag ugcgccaucc     1200

uaagccccgc auucaaagua cgagaguucu caguaaccga ugccgucccg uucccaauaa     1260

gccugauaug gaaccacgac agcgaggaca ccgaaggugu ccacgaaguc uucagucgaa     1320

accacgcggc cccauucuca aaaguauuaa cguuccuccg acgcggaccc uucgaacucg     1380

aagcauucua cagcgacccg caaggcguac cguacccuga ggcaaagauu ggcagguucg     1440

uaguccagaa cgucuccgca cagaaagaug gcgagaaaag ccgcguaaag gucaaagucc     1500

gagucaacac acacggaauc uucaccauuu ccaccgccuc aaugguagaa aaagucccca     1560

cagaagaaaa cgagaugagc ucugaagccg acauggagug ccucaaccaa cgcccacccg     1620

aaaaccccga caccgacaag aacguccaac aagacaacag cgaagcagga acccagcccc     1680

aaguccaaac cgacgcacaa cagaccagcc agagcccacc cucccccgag cucacaucag     1740

aagaaaauaa gaucccagac gcagacaagg ccaacgaaaa gaaagucgac cagcccccgg     1800

aggccaagaa acccaaaauc aaagugguca acguagaacu ccccaucgaa gcaaaccugg     1860

ucuggcagcu agguaaagac uuacuaaaca uguacaucga aaccgaaggc aaaaugauaa     1920

ugcaagauaa acucgaaaaa gaacgcaacg acgccaaaaa cgcagucgaa gaauacguau     1980

acgaguuccg ggacaaacua ugcggcccau acgaaaaauu caucugugaa caagaccacc     2040

aaaacuuucu acgucuauua accgaaaccg aagacuggcu cuacgaagaa ggcgaagacc     2100

aagcaaaaca ggcuuacguc gauaaacugg aagaacuaau gaaaaucgga acgccgguca     2160

aagugcgguu ccaagaagca gaagaacguc ccaaaauguu cgaggaacuc ggacaaagac     2220

uccaacacua cgcgaaaauc gccgccgacu uccgcaacaa agacgagaag uacaaccaca     2280

ucgacgaauc agaaaugaag aaaguagaaa agucggucaa cgaaguaaug gaauggauga     2340

acaacguaau gaacgcccaa gccaaaaagu cccucgacca agacccaguc guccgagcac     2400

aagaaaucaa aaccaaaauu aaggaacuga acaauaccug cgagcccguc guaacgcaac     2460

cgaaaccaaa aauagaaucc cccaaacucg aacgaacccc caacgggccg aacaucgaca     2520

agaaagaaga agaccucgag gacaaaaaca acuucggagc agaaccacca caccaaaacg     2580

gcgaaugcua cccaaacgag aaaaacagcg ucaacaugga ccucgauuaa ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  3581
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt11)

<400>  3581
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

acaaggucag gcggcaacga ccacggaggc gcguauguug ggcgcuaguc gcaguccuac      120

uugcggaccu acuggcacua agcgacacgc uggcaguuau guccguagac cucggaagcg      180

aaucgaugaa agucgcgauc gucaaacccg gcgucccaau ggaaauaguc cuaaacaagg      240

aaagccgcag gaagaccccg gugauaguga cacucaaaga gaacgaacgc uucuucggag      300

acucggccgc gagcauggcc auaaagaacc ccaaagcaac gcuaagauac uuccaacacc      360

uccucgggaa acaagcagac aacccacacg uggcacucua ccaggcaagg uucccagaac      420

acgagcugac auucgacccg caacgccaaa cgguacacuu ccaaauauca ucacaacugc      480

aauuuucacc cgaagaaguc cuaggaaugg ugcucaacua cuccagauca uuagccgaag      540

auuucgccga acaaccaaua aaagacgcag ucauaacagu acccgucuuc uucaaccagg      600

cagaacgccg agcaguccua caagccgcga ggauggcagg ccuuaaaguc cuccaacuga      660

ucaacgacaa caccgcaaca gcacugagcu auggcgucuu cagacggaag gacauaaaca      720

ccaccgcaca gaauauaaug uuuuacgaca ugggaagcgg auccacagug ugcaccauag      780

uaaccuacca aauggugaaa acgaaggagg ccggcaugca accucagcuc caaauccgag      840

ggguaggauu cgaccggaca cucggcgggc uagaaaugga acuacggcua agagaaagau      900

uagcgggacu guucaacgaa cagcgaaaag gacaacgagc gaaagacguc agggaaaacc      960

cccgcgcgau ggcaaagcuc cuucgagagg caaaccgccu gaaaacagug cugucagcga     1020

acgcggacca cauggcucaa auagaaggac ucauggacga cgucgacuuc aaagcaaagg     1080

uaacacgagu cgaauuugaa gaacuaugcg cggaucuauu cgaaagagug cccggacccg     1140

uacagcaagc acugcagucc gccgaaaugu cccuagauga aauagaacaa guuauccuag     1200

ucggcggcgc caccagagua ccacgagugc aggaaguacu acucaaagcc guaggcaagg     1260

aggaacuagg gaaaaacaua aacgccgacg aagcagcagc gaugggggca guuuaccaag     1320

ccgccgcacu cagcaaggca uucaaaguca aacccuucgu cguacgagac gccgucguau     1380

acccgauacu gguagaguuc acacgcgaag uggaggagga accaggaaua cauagccuga     1440

aacacaacaa gcgaguucuc uucagccgaa ugggccccua cccccaaaga aaagugauca     1500

ccuucaaccg guacagccac gacuucaacu uccacauaaa cuacggcgac cucggauucu     1560

uggggcccga agaccucagg guauucggga gccaaaaccu gacaacaguc aaacucaaag     1620

gcguaggcga cagcuucaaa aaguacccag auuacgaaag uaaaggcaua aaagcacacu     1680

ucaaucuuga cgaaagcgga gugcucucgc ucgaccgcgu ggagagcguc uuugaaaccc     1740

uaguagagga cagcgccgaa gaagaaagca cgcuaacaaa gcugggaaac accauauccu     1800

cacuauucgg agggggaacg acaccagacg caaaagagaa cggaaccgac accguccaag     1860

aagaggaaga gagcccagcu gaagggucca aagacgagcc aggagaacaa guugaacuua     1920

aagaagaagc ggaggccccu guugaggacg gaagccaacc gcccccaccc gaacccaaag     1980

gcgacgccac accagaaggc gaaaaggcaa ccgagaagga aaacggagac aaauccgaag     2040

cccaaaaacc aagcgaaaaa gcagaggccg gcccagaagg ggucgcgccc gcaccggaag     2100

gggagaagaa gcaaaaaccc gcacgaaaac gcagaauggu ggaagaaauc ggaguagagc     2160

uagucguacu agaccuacca gaucugccgg aagacaaacu agcacaauca guucagaaac     2220

uucaagacuu gacccuacgg gaccuggaaa aacaagaaag agaaaaagca gccaacaguc     2280

ucgaagccuu caucuucgag acacaagaca aacuguacca acccgaguac caggaaguaa     2340

gcacagaaga acagagagaa gaaaucagug gaaaacugag cgcugcguca acauggcuag     2400

aagacgaagg gguaggugca acaaccguca ugcuuaaaga aaagcucgcc gaacugcgca     2460

aacucugcca agggcuauuc uuccgaguag aagagaggaa gaaauggcca gaaaggcuau     2520

ccgcacuaga caaccuacug aaccacucga gcauguuccu aaagggagca agacucauac     2580

cagagaugga ccaaauauuc accgaggugg aaaugacaac acucgaaaag guaauaaacg     2640

aaacgugggc cuggaaaaac gccacacuag cagagcaagc caaacugcca gcaacagaga     2700

aaccaguacu gcuaucaaag gacaucgaag caaaaaugau ggcacuggac agagaggugc     2760

aauaccuccu caacaaagca aaauucacaa aacccagacc acgaccaaaa gauaagaacg     2820

gaacacgcgc agagccaccc cuaaaugcuu cggcgagcga ucaaggggag aaaguaauac     2880

ccccagccgg gcaaaccgag gacgccgagc cgaucuccga acccgaaaag gucgaaacag     2940

gcucagaacc cggggauaca gaaccacuug aacucggcgg acccggagcc gagccagaac     3000

agaaggaaca aaguacaggg caaaaacgcc cccugaaaaa cgacgaacua uagggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3582
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt11)

<400>  3582
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

aagaaaccca aacacaagau caaccaaugg aagaagaaga aguggaaacc uucgcguucc      120

aggcggaaau agcccaacua augucccuca ucaucaacac cuucuacagc aacaaggaaa      180

ucuuccugcg agaacuuauc agcaacagca gcgacgcccu cgauaagauc agauacgaaa      240

gccuaacuga cccaagcaaa cuagauagcg ggaaagaacu ccacaucaac cuaauaccca      300

acaaacaaga ccggacccuc acaauaguag acaccggaau cggaaugaca aaggcggacc      360

uuauaaacaa ucugggaacc aucgcgaaaa gcgggacaaa ggcauucaug gaagcgcucc      420

aggcaggggc agacauauca augaucggcc aauucggagu cggcuucuac ucagcguacc      480

uaguagccga gaaaguaacc gucauaacca aacacaacga cgaugagcag uacgcguggg      540

agagcagcgc gggaggaucg uucacaguga gaaccgacac aggggaaccg augggacgcg      600

gaacgaaagu aauacuacac cucaaagaag accagaccga auaccucgaa gaaaggcgaa      660

uaaaagaaau agugaagaaa cacucccagu ucaucggaua cccgauaaca cuauucgugg      720

agaaagagcg cgacaaagag gucagcgacg acgaagcaga agaaaaagaa gacaaagaag      780

aggaaaagga aaaagaagaa aaagaaagcg aagacaaacc agagaucgaa gacgugggaa      840

gcgacgaaga agaagaaaag aaagauggag acaagaagaa aaagaagaaa aucaaagaga      900

aauacauaga ccaagaagaa cuaaacaaaa cgaaaccaau cuggacccgg aacccagacg      960

acauaaccaa ugaagaauac ggcgaguucu acaaaucacu cacaaacgac ugggaagacc     1020

accucgccgu aaaacacuuc ucgguagagg gacaacuaga guuccgagcg cuccuguucg     1080

ugccaaggcg agccccauuu gaccuguucg agaauagaaa gaagaaaaac aacauaaaac     1140

ucuacguccg ccgggucuuc aucauggaca acugugaaga acuaauuccg gaauaccuga     1200

acuucauccg cggcguagug gacagcgaag accugccgcu caacaucucg agagaaaugu     1260

uacaacaaag caaaauccuc aaaguaauaa ggaagaaccu cgugaagaaa ugccuggaau     1320

uauucacaga acuagccgaa gacaaagaaa acuacaagaa auucuacgag caauucagca     1380

aaaacauaaa acugggcauc cacgaagaca gccaaaaccg caagaaacua uccgagcucc     1440

uacgcuacua caccuccgca uccggggaug agaugguguc acuaaaagac uacugcacca     1500

gaaugaaaga aaaccaaaaa cacaucuacu acaucacggg cgaaacaaaa gaccaaguag     1560

cgaacucagc cuucgucgag cgccuacgaa aacacgggcu agaagucaua uacaugaucg     1620

aaccaauaga cgaauacugc guccaacaac ucaaagaguu cgaaggaaaa acccucguca     1680

gcguuaccaa agaaggcuug gagcuccccg aagacgaaga agagaaaaag aaacaagaag     1740

aaaagaaaac caaauucgaa aaccugugca aaaucaugaa ggacauacug gaaaagaaag     1800

uagagaaggu cguaguauca aacaggcucg ugaccagccc cugcugcaua gucacaucua     1860

ccuacggaug gacggccaac auggaaagaa uaaugaaggc ccaagcacuc cgcgacaacu     1920

cgacaauggg cuacauggcg gccaagaaac accucgagau caaccccgac cacuccauca     1980

ucgaaacgcu caggcagaaa gccgaagcag acaaaaacga uaaauccgug aaggaccucg     2040

uaauacuccu auaugaaacg gcccuucuaa gcagcggguu cagccucgaa gacccgcaaa     2100

cgcacgcgaa caggaucuac cgaaugauca aacucggccu ugggaucgac gaagacgacc     2160

caacagcaga cgacacgagc gcggccguaa cggaagaaau gccaccacua gaaggcgacg     2220

acgacacgag caggauggag gaaguggacu agggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  3583
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt11)

<400>  3583
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcucaaaacu ggacucgggc aagggccugc acauaaaccu ggucccgaac aagcaaaacc      120

aaacacucac gaucguggac acgcgcauag gcaugaccaa gaccgaccuc auaaacaacc      180

ucgggaccgu gaccaagagc gggaccaagg ccuucaugga ggcccugcaa gcggacgcgg      240

acauaagcau gaucggacac uucggcgugg gcuucuacuc ggccuaccuc guggccaaga      300

aagugaccgu gaucucaaaa cacaacaacg acgagcaaua caccugggaa ucgagcgcgg      360

gcgggagcuu caccgugcgc acggacgagu aaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  3584
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt11)

<400>  3584
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aagaagugca ccacggggaa gaggaagucg aaaccuucgc cuuccaggcc gagauagccc      120

aacucaugag cuuaaucaua aacaccuucu acuccaacaa agaaaucuuc cucagagagu      180

ugauaucaaa cgcaagcgac gcccuggaca agauaagaua cgaaagccua acagacccau      240

caaaacugga cucaggaaag gaguuaaaaa uagacaucau cccaaaccca caagaacgca      300

cgcucacccu cguggacacc ggaauaggaa ugacaaaagc cgaccucaua aacaaucucg      360

gcacgauagc caagagcggg acaaaagccu ucauggaggc ccuacaagca ggagccgaca      420

uaagcaugau cggacaauuc ggcguaggcu ucuacagcgc auaccucguc gccgaaaagg      480

ugguaguaau cacaaaacac aacgacgacg aacaauacgc cugggaaagc agcgccggcg      540

ggagcuucac agucagagca gaccacggcg aaccuauagg acgcgggacu aaaguaaucc      600

uccaccuaaa ggaagaccaa accgaauacu uagaagagcg cagggucaag gaagucguca      660

aaaaacacag ccaguucauc ggcuacccca uaacccucua ccuggaaaaa gagagggaaa      720

aggaaauaag ugacgacgag gccgaggaag aaaaaggaga aaaagaagaa gaagacaaag      780

acgacgaaga aaagcccaag aucgaagacg uaggaagcga cgaagaagac gacucaggaa      840

aggacaagaa aaaaaaaacg aaaaaaauca aagagaaaua caucgaccaa gaagagcuga      900

acaaaacaaa accaaucugg accaggaacc ccgaugacau cacacaagaa gaauacgggg      960

aauucuacaa aucgcuaaca aacgacuggg aggaccaccu cgcgguaaag cacuucagcg     1020

uggaaggaca acucgaauuc agagcacuac uauucauccc aaggagagcg ccauucgacc     1080

uguucgaaaa caagaaaaaa aaaaacaaca uaaagcuaua cguccgacga gucuucauaa     1140

uggacucaug cgacgaacug aucccagaau accuaaacuu cauccggggc guaguagacu     1200

ccgaagaccu cccacucaac aucagccgag aaaugcuaca acagagcaag auacugaaag     1260

ugaucagaaa aaacaucgua aaaaagugcc uagaacuauu cagcgaauua gcagaggaua     1320

aagaaaacua caagaaauuc uacgaagccu ucagcaagaa ccuaaaacug ggcauacacg     1380

aagacagcac caaucgaagg cgccuaagcg aacuacuaag auaccacaca agucagagcg     1440

gcgacgagau gacgagccua uccgaauacg uuagccggau gaaagaaacg caaaagucaa     1500

uauacuacau caccggagag agcaaggaac aaguagcgaa cucggcauuc gucgaacgcg     1560

ugcgaaagcg cggauucgaa gucguauaca ugacggagcc caucgacgag uacuguguac     1620

aacagcucaa agaauucgac ggcaaaagcc uagucucagu aaccaaagaa ggacuagaau     1680

ugcccgaaga cgaagaagag aagaaaaaaa uggaagaauc aaaagccaaa uucgagaacu     1740

ugugcaagcu gaugaaagag auccuagaca aaaagguaga aaaggucacg aucucaaacc     1800

ggcuggugag cucgcccugc ugcaucguca cgagcacaua cggcuggaca gcaaacaugg     1860

aacgaauaau gaaagcacaa gcccucagag acaacucaac caugggguac augauggcca     1920

agaaacaccu cgaaauaaac cccgaccacc cuauaguaga aacgcucagg caaaaggccg     1980

aagcagacaa aaacgacaaa gccguaaaag accucguggu ccugcucuuc gaaacagccc     2040

uacucucaag cggauuuuca cuggaggacc cacaaaccca cagcaacaga aucuaccgaa     2100

ugauuaagcu cggacugggu auugacgagg acgaaguagc cgcggaagag cccaacgcgg     2160

caguccccga cgaaaucccg ccccuggaag gggacgagga cgcaucaaga auggaagagg     2220

ucgacuaggg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  3585
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt11)

<400>  3585
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagag       60

cccuaugggu gcucgggcuc ugcugcguac uacucacguu cggaucaguc cgagcagacg      120

acgaggucga cgucgacgga acggucgaag aagaccuagg aaaaagccgc gaaggcagcc      180

ggacagacga cgaggucguc cagcgagagg aagaggcaau acaacucgac ggucuaaacg      240

ccagccagau acgcgagcuc cgggagaaaa gugaaaaauu cgccuuccaa gcagagguca      300

acagaaugau gaaacucaua auuaacuccc uauacaaaaa caaagaaaua uuccugcggg      360

aacuaaucuc caacgccagc gacgccuuag acaaaauacg acucaucagc cugacagacg      420

aaaacgccuu gagcgggaac gaggaacuaa ccgugaaaau aaaaugcgac aaagagaaga      480

accugcuaca cguaacggau acgggaguag gcaugacacg agaagaacuc gucaaaaacc      540

ucggaaccau agccaagagc ggcacaagcg aguuccucaa caaaaugaca gaagcccagg      600

aggacggcca aucaacgagu gagcuuauag gccaauucgg gguaggguuc uacagcgcgu      660

uccuaguagc ggacaaagua auagucacaa gcaaacacaa uaacgauaca cagcacauau      720

gggaaucaga cagcaacgaa uuuagcguga ucgcggaccc gcggggaaac acgcuuggca      780

gaggaaccac caucacucua guacucaagg aagaggcuuc agacuaucua gaacuggaca      840

caaucaaaaa ccucguaaag aaauacagcc aauucauaaa cuucccgaua uacgucugga      900

gcucgaaaac agaaacagua gaggagccga uggaggagga agaggcagcc aaagaagaaa      960

aagaagaauc ggacgacgaa gcggcagucg aagaagaaga ggaagagaaa aagcccaaaa     1020

ccaagaaagu agagaaaacc guaugggacu gggaacucau gaacgacaua aaacccauau     1080

ggcagcgccc gagcaaagaa gucgaggaag acgaauacaa agccuucuac aagagcuuca     1140

gcaaagaaag cgacgacccg auggccuaua uacacuucac agccgaagga gaggugacgu     1200

ucaaaagcau ccucuucguc ccgacgagcg cccccagggg acucuucgac gaauacggga     1260

guaagaaaag cgacuacauc aaacuauacg uccgacgggu guucauaacc gacgacuucc     1320

acgacaugau gcccaaguac cugaacuucg ucaaaggagu gguagauuca gaugaccugc     1380

cacucaacgu aagcagagag acgcuccaac agcacaaacu gcucaaggua auacgcaaga     1440

agcuagucag gaaaacgcuc gacaugauca aaaagauugc ggacgauaag uacaacgaca     1500

cguucuggaa ggaguucgga acgaacauaa aacuaggcgu aaucgaagac cacagcaacc     1560

gaacaagacu cgcaaaacuc cucagauucc agagcagcca ucaccccaca gacauaacaa     1620

gccuggacca auauguggaa cgaaugaaag aaaaacagga caaaaucuac uucauggcgg     1680

gauccagccg caaagaggca gaaagcagcc ccuucguaga acgacuccua aagaaaggcu     1740

acgaagucau cuacuugacc gaaccaguag acgaauacug cauccaggcc cuucccgagu     1800

ucgacggcaa gagauuccaa aacgucgcga aggaaggcgu aaaauucgac gaaagcgaga     1860

agacgaaaga aucgagggaa gcagucgaga aagaguucga accacugcuc aacuggauga     1920

aagacaaagc gcuaaaagac aagauagaaa aagcgguagu aucgcaacgg cugaccgaaa     1980

gcccaugcgc ccuagucgcg agccaauacg gcuggagcgg gaacauggaa agaauuauga     2040

aagcgcaagc cuaccagaca ggaaaggaca ucagcaccaa cuacuacgcc agccaaaaga     2100

agacguucga aaucaaccca agacacccgc uaauaagaga caugcuacga aggaucaagg     2160

aagacgagga cgacaagacc gugcucgacc ucgcggucgu gcuauucgaa acggccacgc     2220

uuagaagcgg auaccugcua cccgacacga aagccuacgg cgaccgaauc gaacgcaugc     2280

uaaggcucag ucuaaacaua gaccccgacg cgaaagugga agaggaacca gaggaggaac     2340

cagaagaaac ggcagaggac accaccgagg acacagaaca ggacgaggac gaggagaugg     2400

acgucggaac ggacgaagag gaagaaaccg caaaggaauc gaccgcagaa aaggacgagc     2460

uauaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  3586
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt11)

<400>  3586
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

gcgaauuacg agcccuacua cuaugggguc gccgacuccg cccacuacuc cgagcccccg      120

cacucgccgc agucccugga ggaaaaccca uacucugccc ccgaagaaca acagcucaac      180

ucggcccccg ucgcaaccca gccuggucgc uccaggccgg ccgacucuuc uccacacaaa      240

ccgccgaaga caaagaagaa ccccuccaca gcauaaucag cagcaccgag uccguacaag      300

gaagcaccuc caaacacgag uuccaggccg aaaccaagaa acuucucgac aucguagccc      360

gaagucuaua cuccgaaaaa gaagucuuca uccgagaacu uaucucuaac gcauccgacg      420

cacucgaaaa acuacgacac aaacucguau cagacgguca agcacuaccc gaaauggaaa      480

uacaucuaca aaccaacgca gaaaaaggua ccauaacaau ucaagacacg ggaauaggaa      540

ugacgcagga ggaacucguc ucaaaccuag gcacuauagc ccgaagcggc agcaaagccu      600

uccucgacgc ccuccaaaac caagccgaag ccuccuccaa aaucaucggu caguucggcg      660

uaggcuucua uuccgccuuc augguagcag accgagucga aguauauucu cgcucagcag      720

cccccggcuc ccuaggcuac caauggcuau ccgacggcag cggcguguuc gaaauagcag      780

aagccucggg cguccguaca ggcaccaaaa ucaucauaca ccuaaaaagc gacugcaaag      840

aauuuagcuc agaagcccgc guccgagacg ucgucaccaa auauucaaau uucgucucau      900

uuccacucua ucuaaacggc agacgcauga acacgcucca agccaucugg augauggacc      960

caaaagacgu ccgcgaaugg cagcaugaag aguucuaccg cuacguagca caagcgcacg     1020

acaaaccacg cuacacccuc cacuacaaaa cggacgcccc acuaaacauc cgcuccaucu     1080

ucuacguacc ggacaugaaa cccagcaugu ucgacguauc ccgcgaacuc ggcucaucgg     1140

uagcacucua cucuaggaaa guccucauac aaacaaaagc caccgacauc cuaccaaaau     1200

ggcuucgauu caucagaggc gucgucgaca gugaagacau cccccucaac cucucacgag     1260

aacuccuaca agaauccgcc uuaauccgaa aacuccgcga cguacuucaa cagcgucuca     1320

uaaaauucuu caucgaucaa uccaagaaag augcagaaaa auacgccaaa uucuucgaag     1380

acuacggccu cuucaugcgg gaaggcaucg uaacagcaac cgagcaagag gucaaagagg     1440

acauagcaaa acuccucaga uacgagucca gcgcccuucc cucgggccaa cuaacuagcc     1500

uaagcgaaua cgccucacgu augagagcag gcacccgcaa caucuacuac cucugcgccc     1560

caaaccgaca ccucgcagaa cacucacccu acuacgaggc caugaaaaag aaagacaccg     1620

aaguccuguu cugcuuugaa caauucgacg aacugacccu acuacaccuc agagaguucg     1680

acaaaaagaa acucaucagc gucgagacgg acaucgucgu agaccacuac aaagaagaaa     1740

aauucgagga ccgcagccca gccgcagaau gccuaucgga aaaagaaacc gaagaacuca     1800

uggccuggau gcggaacguc cuaggcucca gaguaaccaa cguaaaaguc acacucagac     1860

uagacaccca ccccgccaug gucaccguac uagaaauggg agcugcccga cacuuccuac     1920

gaaugcaaca acuagcaaaa acacaggagg aacgcgccca acuccuucaa ccaacccucg     1980

aaauaaaccc ccgacacgcc cuaauaaaga aacuaaauca acugagggcc uccgagcccg     2040

gacucgccca acuucuaguc gaccagaucu acgaaaacgc caugaucgcg gcaggccuag     2100

uagacgaccc ccgcgccaug gugggacgac uaaaugaacu acuugucaaa gcacuagagc     2160

gacauuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  3587
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt11)

<400>  3587
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

aaaucuccuc ccuccccacc caacucuuca aaugcugcuu cugcgacuuc cuaaaaguca      120

aaaugcacac cauguccucc ucccaccucu ucuaccuagc ccucugccuc cuuaccuuca      180

ccuccuccgc caccgccggc cccgaaaccc ucugcggcgc cgaacucguc gacgcccucc      240

aauuugucug cggcgaccgc ggauucuacu ucaacaaacc caccggcuac ggcuccuccu      300

cccgccgcgc accccaaacc ggcaucgucg acgaaugcug cuuccgcucc ugcgaccucc      360

gccgccucga aauguacugc gcaccccuca aacccgccaa auccgcccgc uccguccgcg      420

cccaacgcca caccgacaug cccaaaaccc aaaaagaagu ccaccucaaa aacgccuccc      480

gcggcuccgc cggcaacaaa aacuaccgca uguaaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  3588
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt11)

<400>  3588
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

uccccauggg caaauccaug cucguccucc uaaccuuccu cgccuucgcc uccugcugca      120

ucgccgccua ccgacccucc gaaacacucu gcggcggcga acucgucgac acccuccaau      180

ucgucugcgg cgaccgcggc uucuacuucu cccgccccgc cucccgcguc ucacgccgcu      240

cccgcggcau cgucgaagaa ugcugcuucc gcucuugcga ccucgcccuc cucgaaaccu      300

acugcgccac ccccgcaaaa uccgaacgcg acgucuccac cccccccaca guacuccccg      360

acaacuuccc ccguuacccc gucggcaaau ucuuccaaua cgacaccugg aaacaaucca      420

cccaacgccu ccgccgcgga cuacccgccc uacuccgcgc ccgccgcggc cacguccuag      480

caaaagaacu cgaagccuuc cgagaagcca aacgccaccg cccccucauc gcccucccca      540

cccaagaccc cgcccacgga ggcgcccccc ccgaaauggc cuccaaccgc aaauaaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  3589
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt11)

<400>  3589
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

ccuucuccac cuccgccuuc ggccccgucg ccuucucccu cggccuccua cucguacucc      120

ccgccgccuu cccagccccc guccccccag gcgaagacuc caaagacguc gccgcccccc      180

accgccaacc ucucaccuca uccgaacgca ucgacaaaca aauacgcuac auccucgacg      240

gcaucuccgc ccuccgcaaa gaaaccugca acaaaucaaa caugugcgaa uccucaaaag      300

aagcccucgc cgaaaacaac cuaaaccucc ccaaaauggc cgaaaaagac ggcugcuucc      360

aauccggcuu caacgaagaa acaugccucg ucaaaauaau caccggacuc cucgaauucg      420

aagucuaccu cgaauaccua caaaaccgcu ucgaaucauc cgaagaacaa gcccgcgccg      480

uccaaauguc aaccaaaguc cucauccaau uccuccaaaa aaaagccaaa aaccucgacg      540

ccaucacaac ccccgacccc accaccaacg ccucccuacu caccaaacuc caagcccaaa      600

accaauggcu ccaagacaug accacccacc ucauccuccg cuccuucaaa gaauuccucc      660

aauccucccu ccgcgcccuc cgacaaaugu agggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  3590
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt11)

<400>  3590
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uccuguggcu ccgcggauuc cuccuagcaa gcugcuggau aauaguacga agcuccccaa      120

caccaggcag cgagggccac agcgccgcac ccgacugccc auccugcgca cucgccgccc      180

ucccaaaaga cgucccgaac agccaacccg aaauggucga agcggucaag aaacacauac      240

ucaacaugcu acaccuaaag aaacgcccag acguaacaca gccagucccc aaagccgcac      300

uacuaaacgc gauccgaaaa cuacacguag gcaaaguggg agaaaauggc uacgucgaaa      360

ucgaagacga cauaggcaga cgagcagaaa ugaacgaacu aauggaacaa acaagugaaa      420

uaaucacauu cgccgagagc ggcacagccc ggaaaacccu acacuucgaa aucucaaaag      480

aaggauccga ccucagcguc guagaacgag ccgaagugug gcuauuccuc aaagucccca      540

aagccaacag aaccagaacc aaagucacaa ucagacucuu ccaacagcaa aaacacccgc      600

aaggaagccu cgacacaggc gaagaagcag aggaagucgg acucaaaggu gaacgcagcg      660

aacuccuccu guccgaaaaa gucgucgacg cccgaaaaag cacauggcac guauucccag      720

uaagcagcuc cauccaacgc cugcuagacc aagggaaauc aagccuggac guccgcauag      780

caugcgaaca augccaagaa agcggcgcaa gccuaguacu acuagggaaa aagaaaaaga      840

aagaggaaga aggagaagga aagaagaaag gaggcggaga agguggagca ggcgccgacg      900

aagaaaaaga acaaagccac cggccauucc ucaugcuaca agccagacaa agcgaagacc      960

acccacaccg acgacgccga cgaggccucg aaugcgacgg aaaagucaau auaugcugca     1020

agaaacaauu cuucgucagc uucaaagaca uaggguggaa cgacuggauc auagccccaa     1080

gcggcuacca cgccaacuac ugcgaaggag aaugcccaag ccacaucgcc ggaacauccg     1140

ggagcagccu gagcuuccac agcacgguaa uaaaccacua ccgcaugcgc ggccacagcc     1200

cauucgccaa ccucaaaagc ugcugcguac ccaccaaacu acgcccaaug uccaugcucu     1260

acuacgacga cgggcagaac aucauaaaga aagacauaca gaacaugauc gucgaagagu     1320

gcggcugcuc cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  3591
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt11)

<400>  3591
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacg       60

gccuaccagg acgagcccuc ggcgccgcau gccuccuucu ccucgccgcc ggaugguuag      120

gccccgaagc auggggcuca cccaccccac cacccacccc agccgcaccc ccacccccac      180

ccccaccagg auccccagga ggcagccaag acacaugcac cucgugcgga ggcuucagac      240

gcccugaaga acuaggccga gucgacggcg acuuccucga agccgugaaa cgccauauac      300

ucucccgacu ccaaaugcgc ggccgaccca acauaaccca cgccguaccc aaagcagcua      360

ugguaaccgc ccuccgcaaa cuccaugccg gcaaaguccg agaagacggc cgagucgaaa      420

ucccccaccu cgacggacac gccucccccg gcgccgacgg ccaagaacga guaucagaaa      480

ucaucuccuu cgcugaaacc gacggccugg cauccucccg aguccgccuc uacuucuuua      540

uauccaacga agguaaccaa aaccucuucg ucguccaagc cucacuaugg cucuaccuaa      600

aacuacuccc cuacguacuc gaaaaaggca gccgccgcaa aguccgcgua aaagucuauu      660

uccaagaaca aggccacggc gaccgcugga acaugguaga aaaacguguc gaccucaaaa      720

gaucaggcug gcacaccuuc ccccuaaccg aagcuaucca agcacucuuc gaacgaggag      780

aacgaagacu caaccucgac guacaaugcg acucuugcca agaacucgcg guagucccag      840

uauucgucga ccccggcgaa gaaucccaca gacccuuugu aguaguacaa gcgcgacucg      900

gcgacucucg acaccgaauc cgcaaacgcg gccuagaaug cgacggacgc acaaaccucu      960

gcugccgcca acaauucuuc auagacuucc gccuaaucgg cuggaacgac uggaucauag     1020

cccccaccgg cuacuacggc aauuacugcg aaggcucaug ccccgcauac cucgccggcg     1080

uccccggcuc agcauccucu uuccacaccg ccgucguaaa ccaauacagg augcgcggac     1140

uuaacccagg aacagucaau uccugcugca uacccaccaa acucagcacc auguccaugc     1200

ucuacuucga cgacgaauac aacaucguca aacgcgacgu ccccaacaug aucgucgaag     1260

aaugcggaug cgcauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  3592
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt11)

<400>  3592
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

uccguguuuu acugcucaca gcacucacac ugugucacgg auucaaccua gacaccgaaa      120

augcaaugac cuuccaagaa aacgcacgcg gcuucggaca aucgguaguc caacuacaag      180

guucgcgcgu agucgucggc gccccucaag agauagucgc ugcaaaccaa cgaggcucac      240

ucuaccaaug cgacuacuca accgggucau gcgaaccaau cagacuccaa gucccagucg      300

aagcagucaa caugagccug ggucucagcc ucgccgccac aaccucaccc ccacaacucu      360

uagcaugcgg accaaccguc caucagaccu gcucggaaaa caccuacgua aaaggccuau      420

gcuuucucuu uggguccaac cuacgacagc agccccaaaa auuccccgaa gcccuccgag      480

gauguccgca agaagacagc gacauagccu uucucauuga cggcuccgga uccauaauac      540

cacacgacuu ccgccggaug aaggaauuug ucucaacagu uauggaacaa cucaagaaau      600

ccaaaacacu cuucucccug augcaauaca gcgaggaguu cagaauccac uucaccuuca      660

aagaguucca gaacaacccc aacccccgcu cacugguaaa accaauaacu caacuccucg      720

gcaggacaca cacggccacg ggcaucagga aggucgugcg cgaacucuuc aacauaacaa      780

auggugcacg caaaaacgcc uucaaaaucc uuguggucau aaccgacggc gaaaaauucg      840

gggacccauu aggauacgaa gacguaaucc ccgaagcgga cagagaggga guaauccgau      900

acgucaucgg cguuggggac gccuuccgua gcgaaaaauc ccgccaggaa cucaacacaa      960

uugccuccaa accgccccga gaccacgucu uccaagucaa caacuucgaa gcccucaaaa     1020

ccauccaaaa ccaacuccga gagaaaauau ucgccauaga aggaacccaa accggcagcu     1080

ccagcuccuu cgaacaugaa augucccaag aaggcuucag cgccgcgauc accuccaacg     1140

gcccucuacu cucuaccguc ggaucauacg acugggcugg cggcgucuuc cuuuacaccu     1200

ccaaggaaaa aucgacauuc aucaacauga ccagagucga uucugacaug aacgacgcau     1260

aucucggcua cgccgcugcu aucauucuac gcaacagagu gcaaucucua guauuaggag     1320

ccccucguua ccaacacauc ggccuagugg caauguuccg ucaaaacacc gggauguggg     1380

aaagcaacgc gaacgucaag ggcacccaaa ucggcgcaua cuucggagcu ucucucugcu     1440

cuguggacgu cgacucaaac ggaagcacug aucucguucu uaucggagca ccccacuacu     1500

augagcagac ucgaggaggc caaguaucag ucuguccacu cccccguggc cgagcccgcu     1560

ggcaaugcga cgcgguucua uauggcgaac aaggucaacc cuggggcagg uucggugccg     1620

cgcucaccgu ccuuggagac gucaacggcg acaaacucac cgacguagca aucggcgcac     1680

cuggcgagga agacaaccgc ggcgcagugu accucuucca cggcaccucc ggcagcggca     1740

ucucacccuc ccacucacaa cgcauagccg gcucuaaacu gucccccaga cugcaauacu     1800

ucgggcaaag ccuauccggu ggacaagacc ucacgaugga cggccuagua gaucugacgg     1860

uuggcgcgca agggcaugua cuucuacuac gaucccaacc aguacuacgu gucaaggcaa     1920

ucauggaguu caauccacgg gaagucgcac gaaacgucuu cgaaugcaac gaccaaguug     1980

ucaagggcaa agaagccggc gaagucagag ugugucugca cguacaaaag agcacacgug     2040

aucgacugcg agaaggacaa auccaguccg uggucaccua cgaccuagcc cuagacuccg     2100

gaagacccca cagccgugcc gucuucaacg aaaccaaaaa uucaacccgc cggcaaaccc     2160

aggugcuagg ccuuacccaa acuugcgaga cgcucaaacu acaacugccc aacuguaucg     2220

aagacccagu cucaccaauc guacuacgcc uuaauuuuuc ccuagucggc acaccccucu     2280

cagcauucgg aaaccuccga cccguccucg ccgaagacgc ccaacgacuu uucaccgccc     2340

uauuccccuu cgaaaagaac ugcggcaacg acaacauaug ucaagacgac cucagcauca     2400

ccuucucuuu caugucgcuc gacugccuag ugguaggcgg accccgagaa uuuaacguca     2460

cagucaccgu aagaaacgac ggagaggauu ccuacagaac gcaaguuaca uucuucuucc     2520

cgcucgaccu cucguaccgc aaagucucga cccuucaaaa ccaacgaucu caacgaucuu     2580

ggaggcucgc augugaauca gccucgucaa cagaaguaag uggcgcccuc aaaucgaccu     2640

ccuguuccau aaaccaccca aucuuccccg agaacagcga agucacauuc aacauaacau     2700

ucgacguuga cucuaaagca ucacucggca acaaacucuu acugaaagcc aacgucacca     2760

gcgaaaacaa caugccaaga acaaacaaaa cagaguucca acucgaacuc ccagucaagu     2820

augccguaua cauggucguc accagccacg gaguauccac aaaauaccuc aacuuuaccg     2880

ccagcgaaaa cacguccaga guaaugcaac accaauacca gguauccaac cuuggucaac     2940

gcagucuacc caucucccua guguuccucg uucccgucag acuaaaccag acaguaauau     3000

gggaccgucc acaaguaaca uucucugaaa accucuccuc cacaugucac acuaaagaac     3060

gacucccuag ccauuccgac uuucuugcag agcuucgcaa agccccuguu gugaacugcu     3120

caaucgcggu augccagcgc auacagugcg acauaccauu cuuugggaua caggaagagu     3180

ucaacgcgac ucucaaaggu aaccucagcu ucgacuggua uaucaagacc ucacauaacc     3240

accuccuaau aguauccaca gccgaaaucc ucuucaacga cagcgucuuc acauugcugc     3300

ccggccaagg agcuuucgua cgaucgcaga cagaaacuaa aguagaaccu uucgaagucc     3360

cgaacccgcu cccgcuaauc gucggauccu ccguuggcgg gcuacuccuu cuugcccuca     3420

ucacagcagc acuguauaag cucggcuucu ucaagcgcca auacaaagau augauguccg     3480

aaggcggccc gcccggggcc gaaccccagu aaggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  3593
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt11)

<400>  3593
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguucu       60

cccucaaaac cuuaccguuc cuccuacuac uacacgucca aaucuccaaa gccuucccug      120

ucuccagcaa agagaaaaac acuaaaaccg uacaggacua ccucgaaaaa uucuaccaac      180

uacccucaaa ccaguaccag uccacccgca aaaacggcac aaacgugauc gucgaaaagc      240

uaaaagaaau gcaacgcuuc uucggccuaa acgucacagg caaacccaac gaagaaaccc      300

ucgacaugau gaagaaaccc cgaugcggcg uccccgacuc cggcggcuuc augcucacac      360

ccgguaaccc caaaugggaa cgaaccaacc uaaccuaccg cauacgaaac uacacacccc      420

aacucucaga agccgaaguc gaacgagcua ucaaagacgc auuugaacuc ugguccgucg      480

caucaccccu caucuucacc cgcaucucuc aaggcgaagc cgacauaaau aucgccuucu      540

aucaaagaga ccacggcgac aacucccccu ucgacggccc gaacgguauc cucgcacacg      600

ccuuccaacc aggccaagga aucggcggcg augcccacuu cgacgcagaa gaaaccugga      660

caaacaccuc agccaacuac aaccucuucc ucgucgccgc gcacgaguuc ggacauuccc      720

ucggccuagc ccacuccucc gaccccggug cacucaugua cccaaacuac gccuuccgcg      780

aaaccagcaa cuacucacuc ccccaagacg acauagacgg cauccaagcc auauacggac      840

uaucauccaa ccccauccag ccaaccggac ccucaacccc caaacccugc gauccauccc      900

ucaccuucga cgccaucacc acccuacgug gagagauccu cuucuucaaa gaucgauauu      960

ucuggcgccg acacccccaa cugcaacggg uugaaaugaa cuucaucagc cucuucuggc     1020

cuucacuacc caccggaauc caagccgccu augaagacuu ugaccgcgac cucaucuucc     1080

ucuucaaagg aaaccaauac ugggcccucu cggguuacga cauccuucaa ggcuacccua     1140

aagacauauc aaacuacgga uucccaucgu ccguccaagc caucgaugcc gcaguuuucu     1200

accgcuccaa aaccuacuuc uucgucaacg accaauucug gcgcuaugac aaccaacgcc     1260

aauucaugga accaggauac cccaaaucca ucuccggcgc cuuccccggc aucgaaagca     1320

aagucgacgc agucuuccaa caagaacacu ucuuccacgu uuucucaggc ccucgcuacu     1380

acgccuucga ccuaaucgcc caacgaguca cccgagucgc ccgaggaaac aaauggcuua     1440

acugccgcua cggauaggga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  3594
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt11)

<400>  3594
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccc       60

ucuggcaacc ucucguauua guacuccuag uccuuggaug cugcuuugcc gcuccucgac      120

aacgccaauc cacacucguc cuuuucccag gggaucuaag aaccaaccuu accgaccggc      180

aacuagcaga ggaauaccua uaccgcuaug gauacacaag agucgccgaa augagaggag      240

aaucgaaaag ccucggacca gcccuccuac uacuacaaaa acaacucucc cugcccgaaa      300

cuggcgaacu cgacucugcc acucuaaaag caaugaggac cccacgaugc ggcguccccg      360

accuaggcag auuccaaacc uucgaaggcg aucuaaaaug gcaccaccac aacauaaccu      420

acuggaucca aaacuacuca gaagaccucc cccgagccgu aauagacgau gccuucgcaa      480

gagcuuucgc ccucuggucg gcagucacuc cccucaccuu uaccagagua uacucccgag      540

acgccgacau agucauccaa uucggcgucg ccgaacacgg cgacggcuac cccuucgacg      600

gaaaagaugg acuccucgcu cacgcguucc caccaggccc agguauccaa ggcgaugcuc      660

acuucgacga cgacgaacua uggucucucg gaaaaggggu cgucgucccc acccgauucg      720

gaaacgcaga cggcgccgcu ugccacuucc ccuucaucuu cgaaggacgu uccuacagcg      780

ccugcacgac cgacggaaga uccgauggac uaccauggug cucaacgacc gccaacuacg      840

acacagacga cagauucgga uucugucccu cagaacgucu cuacacacaa gacggcaacg      900

ccgauggcaa acccugccaa uuccccuuca uauuccaagg ccaauccuac uccgccugca      960

caaccgacgg acgcucugac ggcuaccgau ggugcgcuac aacagcaaac uaugaucgag     1020

acaaguuauu uggauucugc cccacccgcg ccgauuccac cguaaugggu gggaacuccg     1080

caggagaacu cugcgucuuc cccuucaccu uccucggaaa agaguacagc acaugcaccu     1140

ccgaaggccg aggcgacggc cgccuauggu gcgccaccac cuccaacuuu gacucagaca     1200

agaaaugggg uuucugcccc gaccaagguu acagccucuu ccucgucgcc gcacaugaau     1260

uuggacacgc auuaggccua gaccacucgu caguccccga agcccucaug uaccccaugu     1320

acagauucac ugaaggccca ccccuccaca aagacgacgu caacggaauc cgccaucucu     1380

acggcccccg accagaaccu gaaccacgcc cacccacaac caccacaccc caacccaccg     1440

ccccacccac ugucugcccc accggcccac ccaccgucca ucccagcgag agacccaccg     1500

cgggcccaac cggcccaccc uccgcaggcc ccacuggacc cccaaccgca ggacccucca     1560

ccgcuacuac cguuccacua uccccagucg acgacgcuug caacgucaac aucuucgacg     1620

ccauagcuga gauaggaaac cagcucuacc uauucaaaga cggaaaauac uggcgauucu     1680

ccgagggacg cggcucccgc ccccaaggac cauuucuaau agcagacaag uggcccgcac     1740

ucccacgcaa acuugacucc guuuucgagg aaagacucuc caagaaacua uucuucuuuu     1800

ccggccgaca agucuggguu uacacaggcg ccuccguacu cgguccucgc cgccuugaca     1860

aacuagggcu cggcgcagac gucgcccagg uaacaggagc ucuccgaagc ggaaggggca     1920

aaauguuacu cuucuccggc cgucgacucu ggcgauucga cguaaaagcc caaaugguag     1980

aucccagaag cgccagcgaa gucgaccgca uguucccagg agucccccuu gauacccacg     2040

acgucuucca auaccgcgaa aaagccuacu uuugccaaga ccgcuucuac uggcgcgucu     2100

cuagcagauc agaacuuaac caaguagacc aaguaggcua cgucaccuac gacauccuac     2160

agugcccaga agacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  3595
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt11)

<400>  3595
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ccggcguacu cgcagccuuc cuauuccuau ccuggaccca cugccgcgca uuaccccucc      120

ccucaggagg cgaugaagac gaccuuuccg aagaagaccu gcaauucgcc gaacgcuacc      180

uccgauccua cuaccacccc accaaccucg ccggcauacu caaagaaaac gcagccucau      240

ccaugacaga acgccuccgc gaaaugcaau ccuucuuugg ccucgaaguc accggaaaac      300

uugacgacaa cacgcuagac gucaugaaaa aacccagaug cggagucccc gacgucggcg      360

aauacaacgu cuuccccaga acccuaaaau ggucaaaaau gaaccucacc uacagaauag      420

ucaacuacac cccugacaug acccacuccg aaguagaaaa agccuucaaa aaagccuuca      480

aagucugguc ugacguuacc ccccucaacu ucacccgacu ccacgacggc aucgccgaca      540

uaaugaucuc cuucggaauc aaagaacacg gcgacuucua ccccuucgac ggaccaucag      600

gccuacucgc ccacgccuuc ccaccaggac ccaacuacgg aggcgacgcc cacuucgaug      660

acgacgaaac cuggaccucc uccuccaaag gcuacaaccu cuuccuagua gccgcacacg      720

aauucggcca cucacuagga cuagaccacu ccaaagaccc cggcgcucuu auguucccca      780

ucuacaccua cacugggaaa ucccacuuca ugcuccccga cgacgacgua caaggcaucc      840

aaagccucua cggcccgggc gacgaagauc ccaaccccaa acaccccaaa acaccagaca      900

aaugcgaccc cucacuauca cuagacgcaa ucaccucccu ccguggcgaa acuaugaucu      960

ucaaagaccg auucuucugg cgcuuacacc cccaacaagu cgacgccgaa cucuuccuua     1020

ccaaaucauu cuggcccgaa cuccccaacc gcaucgacgc cgccuacgaa caccccagcc     1080

augaccucau cuuuaucuuc cgcgggagaa aauucugggc acuaaacgga uacgacauac     1140

ucgaaggcua cccaaaaaaa aucuccgaac uaggccuccc aaaggaaguc aaaaagaucu     1200

ccgcagcagu acacuucgaa gacaccggca aaacccuccu auucucaggu aaccaaguau     1260

ggcgcuacga cgacaccaac cacaucaugg acaaagacua cccccgccuc aucgaagaag     1320

acuuccccgg cauaggcgac aaagucgacg ccgucuauga aaaaaacggc uacauauacu     1380

ucuuuaacgg ccccauccaa uuugaauacu ccauaugguc caaccgcauc guacgcguua     1440

ugccagccaa cuccauccuc uggugcuaag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3596
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt11)

<400>  3596
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

ccccgaacac caccgaagau uacgacacca caaccgaguu cgacuacggc gacgccaccc      120

ccugccaaaa agucaacgaa cgcgccuucg gcgcccaacu ccucccaccc cuuuacuccc      180

ucgucuucgu caucggccuc gucggcaaua uccucguagu ccucguccuc guccaauaca      240

aacgacucaa aaacaugacc uccaucuacc uacucaaccu ugccaucucc gaccuccucu      300

uccucuucac ccuccccuuc uggauagacu acaaacucaa agacgacugg gucuucggcg      360

acgccaugug caaaauccuc ucgggcuucu acuacacagg acucuacucc gaaaucuucu      420

ucaucauccu ccuaacuauc gaccgcuacc uagccaucgu ccacgccguc uucgcacuac      480

gcgcccgcac cguaaccuuc ggcgucauca ccucaaucau caucugggcc cucgccaucc      540

ucgccuccau gcccggccuc uacuucucaa aaacccaaug ggaguucaca caccacacau      600

gcucacucca cuucccccac gaaucccuac gcgaauggaa acucuuccaa gcccucaaac      660

ucaaccuauu cggccuaguc cucccacuac ucgucaugau caucugcuac acaggcauca      720

ucaaaauacu ccuccgccgc cccaacgaaa agaaauccaa agcaguccgc cucaucuuug      780

ucauaaugau aaucuucuuc cuauucugga cccccuacaa ccucaccauc cucaucucag      840

uauuccaaga cuuccucuuc acccaugaau gcgaacaauc acgccacuua gaccucgccg      900

uccaagucac cgaggucauu gccuacaccc acugcugcgu caacccagua aucuacgccu      960

ucgucggcga acgcuuccgc aaauaccucc gucaacuauu ccaccgacgc gucgccguac     1020

accucgucaa auggcucccc uuccuaucug ucgaccgacu agaacgcguc uccuccacaa     1080

gcccaagcac cggcgaacac gaacucuccg ccggcuucua gggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  3597
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt11)

<400>  3597
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcgca       60

cacucgccug ccuccuacuc cucggcugcg gcuaccucgc acacguccuc gccgaagaag      120

ccgaaauccc ccgagaaguc aucgaacgac ucgcccgcuc ccaaauccac uccauccgcg      180

accuccaacg ccuccucgaa aucgacuccg ucggcuccga agacucccuc gacaccucac      240

uccgcgccca cggaguccac gccaccaaac acguacccga aaaacgaccc cuccccaucc      300

gccgaaaacg cuccauagaa gaagccgucc ccgccgucug caaaacccgc accgucaucu      360

acgaaauccc ccgcucccaa gucgacccca cauccgccaa cuuccucauc uggccccccu      420

gcguagaagu caaacgcugc accggcugcu gcaacacauc cuccguaaaa ugccaacccu      480

cccgcguaca ccaccgcucc gucaaagucg ccaaagucga auacguccgc aaaaaaccca      540

aacuaaaaga aguccagguc cgccucgaag aacaccucga augcgccugc gccaccaccu      600

cccucaaccc agacuaccgc gaagaagaca ccggccgccc ccgcgaaucc ggcaaaaaac      660

gcaaacgcaa acgccugaaa cccaccuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  3598
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt11)

<400>  3598
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacc       60

gaugcugggc ccucuuccuc agccucugcu gcuaccuacg acuuguauca gccgaaggcg      120

acccaauccc agaagaacua uacgaaaugc uguccgacca cuccauccgc uccuucgacg      180

accuccaacg ccuccuccac ggugaccccg gcgaagaaga cggcgccgaa cuagaccuua      240

auaugacccg cucccacucc ggcggagaac ucgaaucacu cgcccgcgga cgccgcuccc      300

uaggcucccu caccaucgcc gaaccagcca ugaucgccga augcaaaaca cgcaccgaag      360

uauucgaaau cucacgccga cucaucgacc gcaccaacgc caacuuccuu gucuggcccc      420

caugcgucga aguccaacgc ugcuccggcu gcugcaacaa ccgcaacgua caaugccgac      480

ccacacaagu acaacuccgc ccaguccaag uacgcaaaau cgaaaucguc cgcaaaaaac      540

caaucuucaa aaaagccaca gucacccucg aagaccaccu cgccugcaaa ugcgaaaccg      600

uagccgccgc acgccccguc acccgcucac ccggcggauc acaagaacaa cgugcaaaaa      660

ccccccaaac ccgcgucaca auccgcaccg uccgcguccg ccgccccccc aaaggaaaac      720

accgcaaauu caaacacaca cacgacaaaa ccgcccucaa agaaacccua ggcgccuaag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  3599
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt11)

<400>  3599
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

ucuucggccu ccuccuccuc accuccgccc uggccggcca gcgccaaggc acccaggccg      120

aauccaaccu cuccuccaaa uuccaauucu ccuccaacaa agaacaaaac ggcguccaag      180

acccccaaca cgaacgaauc aucaccgucu caacaaacgg cucaauacac ucaccacgcu      240

ucccccacac cuacccaaga aacaccgucc ucgucuggcg ccuagucgcc gucgaagaaa      300

acguauggau ccaacucacc uucgacgaac gcuucggccu cgaagaccca gaagacgaca      360

ucugcaaaua cgacuucgua gaagucgaag aaccuagcga cggcaccaua cucggacguu      420

ggugcggcuc cggcaccguc cccggcaaac aaaucuccaa aggcaaccaa auccgaauac      480

gcuucguauc cgacgaauac uucccauccg aacccggcuu cugcauccac uacaacaucg      540

ucaugcccca auucaccgaa gccgucuccc ccuccguacu accccccucc gcccuccccc      600

ucgaucuucu caacaacgcc aucacggccu ucuccacccu cgaagaccua auacgcuacc      660

uggaacccga aagauggcaa cucgaucucg aagaucuaua ccgccccaca uggcaacucc      720

ucggcaaagc cuucgucuuc ggcagaaaau cccgggucgu agaccucaac cuccucaccg      780

aagaaguacg ccuauacucc ugcacaccac gcaacuucuc cguauccauc cgagaagaac      840

ucaaacgcac cgacacuauc uucuggcccg gcugccuccu cgucaaaaga ugcggcggaa      900

acugcgccug cugucuccac aacugcaacg aaugccaaug cguccccucc aaaguaacca      960

aaaaauacca cgaaguccua caacuucgcc caaaaaccgg cguaagaggc cuccacaaau     1020

cccucaccga cgucgcacua gaacaccacg aagaaugcga cugcgucugc cgcggcucca     1080

ccggaggaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  3600
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt11)

<400>  3600
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

gccuaaucuu cgucuacacc cuaaucugcg ccaacuucug cuccugccga gacaccuccg      120

ccaccccaca auccgccucc auaaaagcac uccggaaugc caacuuacgc cgggacgacc      180

uauaccgucg agacgaaaca auccaaguaa aaggaaacgg cuacgugcaa ucgccccgau      240

ucccaaacuc cuacccacgc aaccuccucc ucaccuggcg acuacacucc caagaaaaca      300

cucgcaucca acucgucuuc gacaaccagu ucggccugga agaagccgaa aacgacaucu      360

gccgcuacga cuucgucgaa gucgaagaca uaucagaaac cuccaccauc auacgcggcc      420

gcuggugcgg ccacaaagag guaccccccc gcaucaaauc ccgcacaaac caaaucaaaa      480

uaaccuucaa aucagacgac uacuucguag cuaaacccgg auucaaaauc uacuacuccc      540

uccuagaaga cuuccaaccc gccgcagcau ccgagaccaa cugggaaucc guaaccuccu      600

ccauauccgg cguauccuac aacagccccu ccgucacaga ccccacccuu auagccgacg      660

cccucgacaa aaaaaucgcc gaauucgaca ccgucgaaga ucuccuaaaa uacuucaacc      720

ccgaaucaug gcaagaagac cucgaaaaca uguaccuaga caccccacga uaccgcggac      780

gcucauacca cgaccgaaaa uccaaagucg accucgaccg acucaacgac gacgccaaac      840

gcuacagcug cacaccacgc aacuacuccg ucaacauccg cgaagagcua aaacucgcca      900

acguagucuu cuucccccgc ugccuucucg uccaaagaug cggcggcaac ugcggcugug      960

gaaccguaaa cuggcgcagc ugcaccugca acucaggcaa aaccgucaaa aaauaccacg     1020

aaguccucca auucgaacca ggccacauca aacgccgcgg ccgagccaaa acaauggccc     1080

ucgucgacau ccagcucgac caccacgaac gcugcgacug cauaugcucc agccgccccc     1140

cucgcuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  3601
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt11)

<400>  3601
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguca       60

cccacuccaa auucccugcc gcaggcaugu cccgaccccu cgacaccucc cuccgacuca      120

aaaccuucuc cucaaagucc gaauaccaac ucgucgucaa cgccguccgu aaacuccaag      180

aauccggcuu cuacuggucc gccgucaccg guggugaagc aaaccuccuc cucuccgcag      240

aacccgccgg caccuuccuc auccgcgacu ccucagacca acgccacuuc uucacccucu      300

cagucaaaac ccaauccggc accaaaaacc uccgcaucca augcgaaggc ggcuccuucu      360

cccuccaauc cgacccacgc uccacacaac cugucccacg cuucgacugc guccucaaac      420

ucguccacca cuacaugcca ccccccggcg cccccuccuu cccauccccc cccaccgaac      480

ccuccucaga aguccccgaa caacccucag cccaaccccu ccccggcucc cccccccgcc      540

gcgcauacua caucuacucc ggcggcgaaa aaaucccacu cguacucucc cgcccccucu      600

ccuccaacgu cgccacccua caacaccucu gccgcaaaac cgucaacggc caccucgacu      660

ccuacgaaaa agucacccaa cuacccggcc ccauccgcga auuccucgac caauacgaug      720

caccccuaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  3602
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt11)

<400>  3602
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucc       60

ccuccgccgg ccaacucgcc cuauucgccc ucggaaucgu ccucgcagcc ugccaagccc      120

ucgaaaacuc caccuccccc cucuccgccg acccccccgu cgccgccgcc gucgucuccc      180

acuucaacga cugccccgac ucccacaccc aauucugcuu ccacggcacc ugccgcuucc      240

ucguccaaga agacaaaccc gccugcgucu gccacuccgg cuacgucggc gcccgcugcg      300

aacacgccga ccuccucgcc gucgucgccg ccucccaaaa aaaacaagcc aucaccgccc      360

ucgucgucgu cuccaucguc gcccucgccg uccucaucau caccugcguc cuaauccacu      420

gcugccaagu ccgcaaacac ugcgaauggu gccgcgcccu caucugccgc cacgaaaaac      480

ccuccgcccu ccucaaaggc cgcaccgccu gcugccacuc cgaaacaguc guuuaaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  3603
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt11)

<400>  3603
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

ccucuggccu ucgacugcuc ccccuccucc ucccccuccu auggcuccua guccuaacac      120

ccggccgccc agccgcaggc cucuccacau gcaaaacaau agacauggaa cucgucaaac      180

gaaaacgcau cgaagcaauc cgcggccaaa uacucucuaa acuucgccuc gccucaccac      240

ccucccaagg cgaaguccca ccaggacccc uccccgaagc cguauuagcu cucuacaacu      300

ccacacgcga ccgcgucgca ggcgagagcg ccgaacccga acccgaaccu gaagcugacu      360

acuacgccaa agaaguaaca cgcguccuca ugguugaaac ccacaacgaa aucuaugaca      420

aauucaaaca auccacccac ucaaucuaca uguucuuuaa cacaucagaa cuccgcgaag      480

ccguccccga accaguccuc cuuucccgug ccgaacuccg ccuacugcgc cucaaacuaa      540

aaguagaaca acacguugaa cucuaccaaa aauacucaaa caauuccugg cgauaccucu      600

ccaaccgccu ccucgccccc uccgacagcc ccgaauggcu cucuuuugac gucacaggcg      660

ucguacgcca auggcucuca agaggcggcg aaaucgaagg cuuccgccuc ucagcccauu      720

gcucuugcga cucucgcgac aacacccucc aagucgacau caacggcuuc accaccggcc      780

gacgcggcga ccucgccacc auccacggca ugaaccgucc uuuccuacuu cuaauggcca      840

caccccucga acgcgcccaa caccuccaau caucacgcca cagacgcgcc cucgacacca      900

acuacugcuu cuccuccacc gaaaagaacu gcugcguacg ccaacucuac aucgacuucc      960

guaaagaccu cggcuggaaa uggauccacg aacccaaagg cuaccacgcc aacuucuguc     1020

uuggcccaug ccccuacauc uggucccuag acacucaaua cuccaaaguc cuagcccuuu     1080

acaaccaaca caaccccggc gcaucagccg cccccugcug cguaccccaa gcccucgaac     1140

cacuccccau agucuacuac guaggccgaa aacccaaagu cgagcaacua uccaacauga     1200

ucguccgguc gugcaaaugc uccuaaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  3604
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt11)

<400>  3604
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugcguccu cuccgccuuc cucauauuac accucgucac cguugcccua ucccucucga      120

cuugcuccac ccucgacaug gaccaauuca ugcgcaaaag aaucgaagca auccgaggcc      180

aaauccucuc aaaacucaaa cuuacauccc ccccugaaga cuauccagaa cccgaggaag      240

uccccccuga agucauaucc auauacaaca gcacccgcga ccuacuccaa gaaaaagccu      300

cgcgacgagc cgcagccugc gaacgcgaac gcagcgacga agaauacuac gccaaggaag      360

ucuacaaaau cgacaugccg cccuucuucc caucagagaa ugcuaucccc cccaccuucu      420

accgaccaua cuuccgcauc guccgcuucg acgucuccgc aauggaaaaa aacgccucca      480

accucgucaa agccgaauuc cgcgucuucc gccugcaaaa ccccaaagcc cgcguucccg      540

aacaacgcau cgaacucuac caaauacuca aauccaaaga ccucaccucu cccacccaac      600

guuacaucga cucuaaagua gucaaaacac gcgccgaagg cgaauggcuc uccuucgacg      660

uaaccgacgc cguacacgaa uggcuccacc acaaagacag aaaccucgga uucaaaaucu      720

cccuacacug ccccugcugc acuuucgucc ccuccaacaa cuacauaauu cccaacaaau      780

ccgaagagcu ugaagcccgc uucgccggca ucgacggaac cucgaccuac acuucaggcg      840

accagaaaac cauuaaaucc acccgcaaaa aaaacucggg caaaacaccc caccuccuac      900

ucaugcuccu cccauccuac cggcuagaau cccaacaaac caaccgacgc aaaaaacgag      960

cccucgacgc agccuacugc uuccguaacg uccaagacaa uugcugccua cgcccacucu     1020

acaucgauuu caaacgugac cucggaugga aauggaucca ugaacccaaa ggcuacaacg     1080

ccaacuucug cgcaggcgca ugccccuacc ucuggagcuc cgacacccaa cacucccgcg     1140

uccuaagccu uuacaacacc aucaaccccg aagccucagc cucccccugc ugcgucuccc     1200

aagaccucga accacuaaca auccucuacu acaucggcaa aacccccaaa auagaacaac     1260

ucuccaacau gaucgucaaa uccugcaaau gcuccuaagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  3605
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt11)

<400>  3605
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

ugcaccucca acgagcccua gucguccucg cacuacucaa cuucgcaacc gucucccuaa      120

gccuuuccac augcaccacc cuggacuucg gccacaucaa aaagaaacgu gucgaagcca      180

uucgaggcca aauacucagc aaacuccgcc ucacaucacc cccagaaccc acaguuauga      240

cccacguccc cuaccagguc cuagcccuau acaacagcac ccgcgaacuc cucgaagaaa      300

ugcacggcga acgcgaagaa ggcugcaccc aagaaaauac agaguccgaa uauuaugcaa      360

aagaaaucca caaauucgac augauccagg gccucgccga acacaacgag cucgccgucu      420

gucccaaagg caucaccucc aaaguauuca gauucaacgu gucauccguc gagaaaaacc      480

gcaccaaccu cuuccgcgcc gaguuccgug uccuccgcgu cccaaacccc uccagcaaac      540

gaaacgaaca acgaauagaa cuauuccaga uccuccgccc cgacgaacac aucgccaaac      600

aacgcuacau ugggggcaaa aaccucccca cccgcggaac agccgaaugg cuauccuucg      660

acgucaccga caccguccgc gaauggcuac uaagaagaga auccaaccuc ggccucgaaa      720

ucuccauaca cugccccugc cacaccuucc aacccaacgg agacauacuc gaaaacaucc      780

acgaaguaau ggaaaucaag uucaaaggag ucgacaacga agacgaccac ggccgcggcg      840

accuaggccg ccucaaaaag cagaaagacc accacaaccc ccaccuaaua cuaaugauga      900

uacccccuca ccgccucgac aaccccggcc aaggcggaca acgcaaaaag cgcgcccucg      960

acacuaacua cugcuuccgc aaccucgaag aaaacugcug cguccgcccc cucuacaucg     1020

acuuccgcca agaccucggg uggaaauggg uacacgaacc caaaggcuac uacgccaacu     1080

ucugcagcgg accaugccca uaccucagaa gcgcagacac aacacacucc accguccucg     1140

gccucuacaa cacccuaaac cccgaagccu cagccucccc cugcugcgua ccacaagacc     1200

uugaaccacu caccauccuc uauuacguag gccgcacccc caaagucgaa caacucucaa     1260

acauggucgu aaaaucaugc aaaugcuccu aaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3606
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt11)

<400>  3606
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

cagucgcagu cugggccgcc cucgccguag gccuugaacu cugggcagcc gcccacgccc      120

ucccagcaca agucgcauuc acucccuacg cacccgaacc cggcuccacc ugccgccuac      180

gcgaauacua ugaccaaaca gcacaaaugu gcugcuccaa augcucuccc ggccaacacg      240

cuaaaguauu cugcacaaaa accucugaca ccguaugcga cucaugcgaa gacuccacau      300

auacccaacu cuggaacugg guccccgaau gccucuccug cggcucccgc ugcagcucag      360

accaaguaga aacccaagcu ugcacccgcg agcaaaaccg caucugcaca ugccgccccg      420

gcugguacug cgcucucucc aaacaagaag gcugcagacu uugugcaccu cugaggaaau      480

gccgaccagg cuuuggugua gcaagacccg guaccgaaac cucagacguc gucugcaaac      540

cgugugcacc cggcaccuuc ucaaacacca ccuccucuac cgacaucugc cgaccacauc      600

aaaucugcaa cguagucgcc aucccaggca acgccuccau ggacgccgua ugcaccucga      660

ccucccccac ccgcuccaug gcccccggcg ccguacaccu accccaaccc gucuccaccc      720

gaucccagca cacccaaccc accccagaac ccagcaccgc cccgucaacc ucauuccuac      780

ucccaauggg ccccucccca cccgcagaag gcuccacagg cgauuucgcc cuccccguag      840

gacuaauagu uggcgucacc gcccuaggcc uccuuaucau cggcguaguc aacugcguca      900

ucaugaccca agucaaaaaa aaaccccucu gccuccaacg cgaagccaaa gucccacacc      960

ucccagccga caaagcccgc ggaacccaag gccccgaaca acaacaccug cucaucaccg     1020

cccccucauc aagcuccucc ucacucgaau cauccgccuc cgcccucgau cgacgcgccc     1080

ccacacgcaa ccaaccacaa gccccaggcg uagaagcguc cggcgccggc gaagcccgcg     1140

ccuccaccgg cucguccgac uccucaccag gaggucacgg cacccaagua aaugucaccu     1200

gcaucgugaa cguuuguucc uccucagauc acagcuccca augcucuucc caagccuccu     1260

ccacaauggg cgacaccgau uccagccccu cagaaucccc caaagacgaa caagucccau     1320

ucucaaaaga agagugugcc uuccgauccc agcucgaaac accagaaacc cuacucgguu     1380

caaccgaaga aaaaccccuc ccccucggcg ucccagacgc aggcaugaaa cccuccuaag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  3607
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt11)

<400>  3607
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgg       60

ucaugcgccu guucccgugc uuucuccagc uacuggccgg gcucgcgcuc ccggccgugc      120

ccccgcaaca augggcgcuc ucggccggaa acgggagcuc ggaaguggaa guggucccgu      180

uccaggaagu gugggggcgc ucguacuguc gagcgcucga gcgcuugguc gaugucguga      240

gcgaguaccc gagcgagguc gagcacaugu ucucgcccuc gugcgugagc uugcuaaggu      300

gcacgggaug uugcggggac gagaacuugc acuguguacc ggucgagacc gcgaacguga      360

ccaugcaauu gcucaagauc aggagcgggg acaggcccuc guacguggaa uugaccuuua      420

gccagcacgu gcgcugugaa ugucgcccgc ucagggaaaa gaugaagcca gagcgcaggc      480

gcccgaaagg gcgagggaaa aggcgcaggg aaaagcaaag acccacggac ugucacuugu      540

gcggggacgc ggucccgagg cgcugaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  3608
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt11)

<400>  3608
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

auagacagac cgacacagcg cccucacccu cguaccaucu cuugccgggg aggaggagaa      120

cgguagacgc ggcggcaucg cgcgggcaag ggccggaacc agcgccaggg ggaggagucg      180

aaggaguggg agcgagaggg gucgcgcuaa aacucuucgu ccaacugcug ggaugcagca      240

gguucggggg agcaguggua agagcaggag aggcagagcc aucgggcgcg gcaaggagcg      300

caagcucggg aagggaggaa ccacagccag aagaagggga agaggaagag gaaaaggaag      360

aagaaagggg accacaaugg agacuaggcg cgagaaagcc agggagcugg acaggggagg      420

cggccgugug cgcggacucg gcaccagccg caagagcgcc gcaggcacua gcaagggccu      480

cgggaagggg aggaagggug gcaagacgag gagccgagga aucaggacca ccacacagcc      540

caagcaggcg agggagcgcg agcagggcag ggcccgggag agcaagcgag acaaugaacu      600

uucucuugag cuggguacau uggucgcuag cgcuccuacu guaucugcac cacgcgaaau      660

ggagccaggc agcgccaaug gcagagggag gagggcagaa ccaccacgaa gucgugaaau      720

ucauggaugu auaccaaagg agcuacugcc acccaauaga aacgcuagua gacauauucc      780

aggaauaucc agaugaaauu gaauacauau ucaaaccgag cugcguacca cucaugaggu      840

guggcggaug cuguaacgau gaagggcuag agugcgugcc aacagaagag agcaacauaa      900

caaugcaaau aaugcgaaua aaaccacacc aaggacagca cauaggagag augagcuucc      960

uacaacacaa caagugcgag ugcaggccaa agaaagacag agcgcgccaa gaaaagaaaa     1020

gcguaagggg aaaggggaag ggacagaaaa ggaaaaggaa aaagaguaga uacaaaaguu     1080

ggagcguaua cguaggagcg agaugcugcu ugaugccgug gucacuaccg ggaccacacc     1140

cgugugggcc cugcagcgag agacgaaaac accuauucgu gcaggacccg cagacgugca     1200

agugcucgug uaagaacacg gacucgaggu gcaaagcgag acagcuagag cugaaugaaa     1260

ggaccugccg augugacaag cccagaaggu agggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3609
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt11)

<400>  3609
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuccuaag cuggguccac uggucccucg cccuacuccu cuaccuacac cacgccaaau      120

ggucccaagc cgcacccaug gccgaaggcg gcggccaaaa ccaccacgaa gucgucaaau      180

ucauggacgu cuaccaacgc ucauacugcc accccaucga aacccucguc gacaucuucc      240

aagaauaccc cgacgaaaua gaauacaucu ucaaacccuc augcgucccc cucaugcgcu      300

gcggcggcug cugcaacgac gaaggacucg aaugcguacc caccgaagaa ucaaacauca      360

caaugcaaau caugcgcauc aaaccccacc aaggccaaca caucggcgaa auguccuucc      420

uccaacacaa caaaugcgaa ugccgcccca aaaaagaccg agcacgacaa gaaaaaaaau      480

ccguccgagg caaaggcaaa ggccaaaaac gaaaaagaaa aaaaucccgc uacaaauccu      540

gguccguaua cgucggcgcc cgaugcugcc ucaugccaug gucccucccc ggcccccacc      600

caugcggccc cugcuccgaa cgccgcaaac accucuucgu ccaagacccc caaaccugca      660

aaugcuccug caaaaacacc gacuccagau gcaaagcccg ccaacucgaa cucaacgaac      720

gcaccugccg cugcgacaaa ccccgacgcu aaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  3610
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt11)

<400>  3610
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccc       60

cccuccuccg ccgccuccuc cucgcagccc uacuccaacu agcccccgca caagcccccg      120

ucucccaacc cgacgccccc ggccaccaac gcaaaguagu cuccuggaua gacgucuaca      180

cccgcgccac cugccaaccc cgcgaagucg uagucccccu cacagucgaa cucaugggca      240

cagucgccaa acaacucgua cccucaugcg ucaccgucca aagaugcggc ggcugcugcc      300

ccgacgacgg ccucgaaugc guccccaccg gccaacacca aguccgcaug caaauacuca      360

ugauccgaua cccaucaucc caacuaggag aaaugucacu cgaagaacac ucucaaugcg      420

aaugcagacc caaaaaaaaa gacucagccg uaaaaccaga ccgcgccgca acaccccacc      480

accgccccca accacgauca guccccggcu gggacuccgc ccccggcgcc cccucccccg      540

ccgacaucac ccaccccacc cccgcccccg gcccauccgc ccacgccgcc cccuccacca      600

ccucugcccu aacccccggc cccgccgccg ccgccgcaga cgccgccgcc ucauccgucg      660

ccaaaggcgg cgccuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  3611
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt11)

<400>  3611
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

uccuaggcuu cuucagcguu gccugcuccc uacuggccgc cgcccuccuc ccuggccccc      120

gcgaagcucc cgcagccgca gcagccuuug aaucaggucu cgaccuuagc gacgcagaac      180

ccgacgccgg agaagcuacc gccuacgcga gcaaagaccu cgaagaacaa cugcgauccg      240

ucuccuccgu cgacgaacuc augacuguac ucuaccccga auacuggaaa auguacaaau      300

gccaacuccg gaaaggaggc uggcaacaca acagagaaca agccaaccuc aacucccgaa      360

ccgaagaaac uaucaaauuc gccgcagccc acuacaacac cgaaauacuc aaaucaaucg      420

acaacgaaug gagaaaaacc caaugcaugc cccgagaagu cugcaucgac gucggcaaag      480

aguucggagu cgccaccaac acauucuuca aaccaccuug uguauccguc uaccgaugcg      540

gagguugcug caacuccgaa ggccuacaau gcaugaacac cuccaccuca uaccucucaa      600

aaacacucuu cgaaaucacc gucccccuaa gccaaggccc gaaaccaguc accauuuccu      660

ucgcaaacca uacaucaugc cgauguaugu caaaacucga cgucuaccgc caaguccacu      720

ccauaauccg acgcucacuc ccagccaccc ucccccaaug ccaagcagca aacaaaaccu      780

gcccaaccaa cuacaugugg aacaaccaca ucugccgcug ccucgcacaa gaagacuuca      840

uguucagcuc cgacgccggc gacgacucca ccgacggcuu ccacgacauc ugcggcccca      900

acaaagaacu cgacgaagaa acaugccaau gcguuugucg cgccggccuc cgcccagccu      960

ccugcggacc acacaaagaa cucgacagaa acuccugcca augcguuugc aaaaacaaac     1020

uauucccauc ccaaugcgga gccaaccgcg aguucgacga aaauaccugc caaugcguau     1080

gcaaacgaac cugcccccga aaccaacccc uaaaccccgg caaaugcgcu ugcgaaugca     1140

ccgaaucccc gcaaaaaugc cuccucaaag gaaagaaauu ccaccaccaa accugcuccu     1200

gcuaccgccg acccugcacc aaccgucaaa aagcgugcga acccggauuc uccuacuccg     1260

aagaagucug ccgcugcguc cccagcuacu ggaaacgccc ccaaaugucc uaaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  3612
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt11)

<400>  3612
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguacc       60

gagaaugggu cgucgucaac guauucauga ugcucuacgu acaacucguc caaggcagca      120

gcaacgaaca cggccccguc aagagaucca gccaaagcac ccuagaacga uccgaacaac      180

aaauacgcgc agccucaagc cucgaagagu uacuacgaau cacccacuca gaagacugga      240

agcucuggcg augccgccuc cgccucaagu ccuucaccuc cauggacagc agaucagccu      300

cccaccgcuc aacccguuuc gccgccaccu ucuacgacau cgaaacccuc aaagucaucg      360

acgaggaaug gcaacgaaca caaugcucuc ccagagaaac cugcguagaa gucgccuccg      420

aacuugguaa aucaaccaac acuuucuuca aaccacccug cgucaacguc uuccgcugcg      480

gaggcugcug caacgaagag ucccucauau gcaugaacac auccaccucc uacaucucca      540

aacaacucuu cgaaauaucc guaccccuaa ccuccguccc agaacuugua cccgucaaag      600

ucgccaacca caccggcugc aaaugccucc ccacagcacc ccgccacccc uacuccauaa      660

uccgccgauc gauacaaaua ccggaagaag accgcugcuc acacucaaag aaacucugcc      720

ccauagacau gcucugggac uccaacaaau gcaaaugcgu ccuccaggaa gaaaaccccc      780

uagccggcac agaagaccac ucccaccucc aagaaccagc ccucugcggc ccccauauga      840

uguucgacga agaccgcugc gaaugcguau gcaaaacccc cugccccaaa gaccucaucc      900

aacaccccaa aaacugcuca ugcuucgaau gcaaagaauc acucgaaacc ugcugccaaa      960

aacacaaacu cuuccacccc gacacaugcu caugcgaaga ccgaugcccc uuccacaccc     1020

gccccugcgc cuccggcaaa accgccugcg ccaaacacug ccgauuccca aaagaaaaac     1080

gcgccgccca aggcccccac ucacgcaaaa auccauaagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  3613
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt12)

<400>  3613
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggauu       60

ccgacgaaac cggcuuugaa cacucaggau uauggguauc aguauuagca ggacuacuac      120

uaggagcaug ccaagcacac ccaauaccag acucaucacc auuauuacaa uucggaggac      180

aaguaagaca aagauaccua uacacagacg acgcucaaca aacagaagca cauuuagaaa      240

uaagagaaga cggaacagua ggaggcgcag ccgaccaauc accagaaucu uuacuacaau      300

uaaaagcacu aaaaccaggc guaauacaaa uauuaggagu aaaaacauca agauucuuau      360

gccaaagacc agauggagca cuauacggau cacuacacuu ugacccagaa gcaugcucau      420

ucagagaauu acuauuagaa gacggauaua acguauacca aucagaagca cauggacuac      480

cccuacaccu accaggaaac aaaucaccac aucgagaccc agccccaaga ggccccgcaa      540

gauuccuacc acuaccagga cuaccaccag cacuaccaga accaccagga auauuagcac      600

cacaaccacc agauguagga uccuccgacc cauuaucaau gguaggacca ucacaaggaa      660

gaucuccauc auacgcauca uaaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  3614
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt12)

<400>  3614
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcauu       60

cauucccacc ucuauuacua cuauuauuuu gggguguugu aucccacuca uuuccagcua      120

cauuagaaac acaagaacaa gacguagauc uaguccaaaa auaucuagaa aaauacuaca      180

accuaaaaaa cgacggacgc caaguagaaa aaagaagaaa caguggacca guaguagaaa      240

aacuaaaaca aaugcaagaa uuuuuuggac uaaaagucac aggaaaaccu gaugccgaaa      300

cuuuaaaagu aaugaaacaa ccaagaugcg gcguaccuga cguagcacaa uucgucuuaa      360

cagaaggaaa cccaagaugg gaacaaacgc acuuaacaua ucgaaucgaa aauuacacac      420

cagaccuacc aagagcagac guagaucacg caauagaaaa agccuuccaa cuauggucaa      480

auguaacacc ccuaacauuc acaaaaguau cagaaggaca agcagauaua augaucucau      540

ucguaagagg ggaucacaga gauaacucac ccuucgaugg cccaggagga aaccuagcac      600

acgcauucca accuggacca ggaauaggug gugaugcaca uuucgacgaa gacgaaagau      660

ggacaaacaa cuucagagaa uauaaccuac acagaguagc agcucacgaa cuaggucauu      720

cauuaggacu aagucauuca acagauauag gagcacuaau guacccauca uacacuuuua      780

gcggagacgu acaacuagca caagacgaca uagauggaau acaagcaaua uacggaagau      840

cacaaaaccc cguacaacca auaggaccac aaacaccaaa agcaugugac ucaaaacuca      900

ccuucgacgc aauaacaacc auaagaggag aaguuauguu cuuuaaagac agauucuaca      960

ugagaacaaa ucccuuuuac ccagaaguag aauuaaacuu caucucagua uuuuggcccc     1020

aacuaccaaa uggucuagaa gcagccuacg aauuugcuga uagagaugaa guaagauucu     1080

ucaaaggaaa caaauauugg gccguccaag gacaaaacgu auuacacgga uauccaaaag     1140

auaucuacuc cucauucggc uuuccaagaa caguaaaaca uauugaugca gcacuauccg     1200

aagaaaacac aggaaaaaca uacuucuuug uagccaacaa auacuggaga uaugaugaau     1260

acaaaagauc gauggaccca ggauacccca aaaugauagc acacgacuuu ccaggaauag     1320

gacacaaagu agaugcagua uucaugaaag acggauucuu cuacuucuuc cacggcacca     1380

gacaauacaa auuugacccc aaaacaaaac gcauccuaac auuacaaaaa gcaaauucau     1440

gguuuaacug uagaaaaaac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  3615
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt12)

<400>  3615
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

cauucccacc acuauuauua cuacuauucu ggggaguagu aucacacucc uucguauuaa      120

cugaaggaaa uccucgaugg gaacaaaccc accucacaua uagaauagaa aacuacacac      180

cagaccuacc uagagcagac guagaccacg caauagaaaa agccuuccaa uuauggucca      240

acgucacacc auuaacuuuc acuaaagucu cagaaggaca agcagauaua augauauccu      300

uugucagagg agaucacaga gacaacucac cauuugacgg accaggagga aaucuagcac      360

acgcauucca acccggaccc ggaauaggug gagacgcaca cuucgaugaa gaugaaagau      420

ggacaaacaa uuucagagaa uacaauuuac acagaguagc agcacacgaa cucggacacu      480

ccuuaggacu cucccauuca accgacauag gagcauuaau guacccauca uacacauucu      540

caggagacgu ccaacuagca caagacgaua ucgacggcau acaagcuaua uacggaagau      600

cacaaaaccc aguacaacca aucggaccac aaacaccaaa agccugugac ucaaaauuaa      660

cuuuugaugc aaucacaacu auacgaggcg aaguaauguu uuucaaagac agauucuaca      720

ugagaacaaa ccccuuuuac ccugaaguag aacuaaacuu cauaucuguu uucuggccac      780

aacuaccaaa cggauuagaa gcagcauacg aauuugccga cagagacgaa guuagauucu      840

ucaaaggaaa caaauacugg gcaguucaag gacaaaacgu cuuacacgga uauccaaaag      900

auauauacuc cucauucgga uucccaagaa ccguaaaaca caucgaugcc gcauuaucag      960

aagaaaauac aggcaaaaca uacuucuuug uugcaaacaa auauuggaga uacgacgaau     1020

acaaacgcuc uauggaccca ggcuauccaa aaaugauugc acacgauuuc ccaggaauag     1080

gacacaaagu agaugcagua uucaugaaag acggauucuu uuauuucuuc cacggaacaa     1140

gacaauacaa auucgaucca aaaacaaaaa gaauccuaac cuuacaaaaa gccaacucau     1200

gguucaauug cagaaaaaau uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  3616
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt12)

<400>  3616
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

aaaacauacu gaaaaucuua auggacuccu acuccaaaga aucaaaaauc caaacaguaa      120

gacguguaac aucaguauca cuccuggcag uauaccuuac aaugaacacu ucuuccuuag      180

uauuagccaa accaauagag aauacuaaug acacaucaau caaaaaugua gaaaaauuac      240

gaaaugcacc caacgaagaa aacagcaaga aaguagaaga uuccaaaaac gacaaaguag      300

aacauguuaa aaacauagaa gaagcuaaag uagaacaagu ugcuccggaa gugaaaucaa      360

aaucaacguu gagaagugca aguauagcaa acaccaacuc cgaaaaauau gacuucgaau      420

acuuaaaugg acuaucguac acagaauuaa caaauuuaau uaaaaacaua aaauggaauc      480

aaauaaaugg ucuguucaac uauaguaccg gcucccaaaa auucuucgga gauaaaaauc      540

guguucaagc uauaauaaau gcacuacaag aaucugguag aacauauacc gcuaacgaua      600

ugaaaggaau agagacuuuu acggaagucc uaagagccgg auucuacuua ggauacuaua      660

acgaugguuu aaguuauuua aaugacagaa auuuucaaga caaaugcaua ccggcaauga      720

uagcaauaca gaaaaacccu aacuuuaagc uaggaacagc uguccaagac gaaguaauua      780

caucacuagg uaaacuuauc ggaaaugcaa gcgcaaacgc agaagucgua aauaauugug      840

ucccaguacu aaaacaauuu agagaaaauu uaaaccaaua ugcuccagac uauguaaaag      900

gaacagcagu aaaugaacuu auaaaaggua uagaguucga cuucucagga gcagcauaug      960

aaaaagacgu aaaaacaaug ccaugguaug gaaaaaucga uccauuuaua aaugaauuga     1020

aggcauuagg ccuauaugga aauauaacca gcgcgacaga augggcauca gacgucggaa     1080

uuuacuaccu uaguaaauuc ggacuauaua gcacaaauag aaaugacaua guacaaagcc     1140

ucgaaaaagc gguagauaug uacaaauaug gaaaaauagc uuucguagcc auggaacgaa     1200

uaacauggga cuaugauggu auagguucaa acggaaagaa agucgaccac gauaaauucc     1260

uagacgaugc ugaaaaacac uacuuaccaa aaaccuacac guucgauaau ggaacuuuua     1320

uaauacgugc uggagacaaa guuucagaag agaaaaucaa aagauuauau ugggcuucgc     1380

gagaaguaaa aucucaauuc caccgaguag uaggaaacga uaaagcauua gaaguuggaa     1440

augcggacga uguauuaaca augaaaauuu ucaacucacc cgaagaauau aaauuuaaua     1500

cuaacauuaa cgguguaagc acagauaacg gagguuuaua cauagaaccu cgaggaacau     1560

uuuauacgua ugaacgaaca ccacaacaaa gcauauuuuc guuagaagaa cuauuuagac     1620

augaauauac acauuaccua caagcacgau acuuaguaga uggauuaugg ggucaaggac     1680

ccuuuuacga aaagaaucgc cucacauggu ucgaugaagg caccgcugag uucuuugcug     1740

gcucgacgag aacaagugga gugcucccaa gaaaaaguau cuuaggauac cuugcaaaag     1800

auaagguuga ccaucguuau ucacuaaaga aaacuuuaaa uucagguuac gacgacagug     1860

auuggauguu uuacaauuac ggauuugcag uagcacauua ucucuacgaa aaagacaugc     1920

ccaccuuuau aaaaaugaau aaagcaauuu uaaacaccga uguaaaaucc uacgaugaaa     1980

uaauuaagaa acugagugau gacgccaaca aaaauaccga auaucaaaau cacauccaag     2040

aauuagccga caaauaccaa ggagcaggua uaccgcuagu gagugaugac uaucucaaag     2100

accacggcua uaagaaagca ucugaaguuu acuccgaaau uagcaaagcg gcaucacuca     2160

ccaauacuag cgucaccgca gaaaaauccc aauacuuuaa uacauuuacu cuucgaggca     2220

cauacacagg agaaacgagc aaaggagaau uuaaagacug ggacgaaaug aguaagaaac     2280

ucgauggaac auuagaauca uuagccaaaa acuccuggag uggcuacaaa acacuuacug     2340

cauacuucac aaauuauaga guaacaagug auaauaaagu acaauaugau guagucuuuc     2400

acgguguauu aacagauaau gcagauauau caaacaacaa agcaccaaua gcaaaaguaa     2460

cuggaccauc aacaggggcu gucgggagaa auauugaguu cucaggcaaa gauucaaaag     2520

acgaagaugg uaaaauuguu ucguacgauu gggauuuugg cgacggagca acaagucgug     2580

guaaaaacag uguacaugcc uacaagaaag ccggaaccua caauguaaca uuaaaaguaa     2640

ccgacgacaa aggagcaacc gccacagaaa guuuuacuau agaaauuaaa aaugaagaca     2700

caacaacccc cauaacuaaa gaaauggaac caaacgacga cauaaaagaa gcaaauggac     2760

cgaucguaga aggaguuacc guuaaaggag acuuaaacgg cucagaugac gcagauacuu     2820

uuuacuucga ugucaaagaa gacggagaug ucacaauaga auuacccuac aguggaucuu     2880

caaacuuuac cuggcuaguc uauaaagaag gagaugacca aaaucauaua gcaagcggaa     2940

uagauaaaaa caacagcaaa guaggcacau ucaaaaguac aaaaggcagg cauuacguau     3000

uuauauacaa acacgauucu gccucaaaca uuucuuacag uuuaaauauu aaaggucuag     3060

gaaaugaaaa acuaaaagaa aaagaaaaca acgacucauc ugacaaagca acaguaauac     3120

cuaacuucaa cacaacaaug caaggaucau uacuaggaga ugacaguaga gauuacuauu     3180

cauuugaagu aaaagaagaa ggugaaguaa auaucgagcu agauaagaaa gacgaauuug     3240

gagugacaug gacccuucac ccagaaucaa auauaaacga ucgaauaaca uauggacaag     3300

ucgauggcaa caaaguauca aauaaaguua aauuaagacc aggaaaauau uaucuccuug     3360

uauacaagua uucaggcagu ggaaacuaug aauugagagu aaacaaauga ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  3617
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt12)

<400>  3617
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

gggucacauu uauuucacua cuguuuuuau ucucaucagc auauaguaua gcaaauacaa      120

acagugaaaa auacgauuuc gaauaucuca acggauuguc auauacagaa cuuaccaacc      180

uuauuaaaaa uauaaaaugg aaccaaauaa auggucuauu uaauuacagu acggguucgc      240

agaaauucuu uggagauaaa aaccguguac aggccauaau aaacgcacua caggaauccg      300

gacgcaccua uacggcuaau gauaugaaag gaauagaaac uuuuacugaa guacuaagag      360

ccggauuuua ucucggauau uacaaugaug gauugaguua ccuaaacgau aggaacuuuc      420

aagacaaaug uauuccagca augauagcaa uacagaaaaa ccccaacuuc aaauuaggca      480

cagccguaca agacgaaguu auaacuucau uaggaaaauu aaucgguaac gcaagcgcaa      540

acgccgaagu aguaaauaau uguguaccag uacuaaaaca auucagagaa aaccucaacc      600

aauacgcacc cgauuacgua aaagggacag caguaaauga auuaauaaaa gguaucgaau      660

uugacuucuc cggagcagcu uaugaaaaag acguuaaaac uaugcccugg uacggaaaaa      720

uagauccuuu uauaaaugaa cucaaagcau uaggacucua ugggaauaua acaucggcua      780

cugaaugggc cagcgacgua ggaauauauu auuuaucaaa auuugggcua uacucaacga      840

acaggaauga uauaguacaa ucgcuagaaa aagccguaga cauguauaaa uaugguaaaa      900

uugcauucgu cgcaauggaa agaauuacau gggauuauga cggaauaggg uccaacggca      960

agaaaguaga ucacgauaaa uuuuuagacg acgcugaaaa acauuauuua ccaaaaacau     1020

auacuuuuga caacgguaca uucaucauua gggcaggaga uaaaguuucc gaagagaaaa     1080

uaaaaagauu auacugggca agucgagaag uaaaaucaca auuccacaga guaguaggca     1140

acgauaaagc cuuagaaguc gguaaugcug acgauguauu aaccaugaaa auauucaaca     1200

guccugaaga auacaaauuu aauaccaaua uaaauggagu aaguaccgau aauggcggac     1260

uauacauaga accucgagga accuucuaca cguacgaacg aacuccgcaa caaucaauau     1320

uuagucuaga agaacuauuu cggcaugaau auacgcacua cuuacaagcu agauaucuug     1380

uagacggauu augggggcaa ggacccuucu augaaaagaa ucgauuaaca ugguuugacg     1440

aaggaacugc ugaauuuuuc gcagguucaa caagaacguc aggaguacua ccaaggaaaa     1500

guauacuagg cuaccuugca aaagauaaag uugaucaucg auauucacua aagaaaacac     1560

uaaauagugg uuaugacgac ucagauugga uguucuauaa cuaugguuuu gcaguggcac     1620

auuaucuaua ugaaaaagau augccaaccu ucauaaaaau gaacaaagcc auauuaaaua     1680

cugacgucaa aucauacgac gaaauaauua agaaauuauc agacgaugca aacaaaaaua     1740

cagaauauca aaaccauaua caagaauuag cagauaaaua ucaaggugca gguauuccau     1800

uaguaucgga ugauuauuua aaagaucaug gauacaagaa agccagcgaa guauacucug     1860

aaauuagcaa agcagcguca cucacgaaua caucuguuac ugcagaaaaa ucacaauauu     1920

uuaauacauu uacacugcgu ggaaccuaua ccggagaaac aucaaaaggu gaauuuaaag     1980

acugggacga aaugucaaag aaacuagaug gaacccucga aaguuuagcc aaaaauucau     2040

ggaguggaua uaaaacucuu acugcauacu ucacuaauua cagaguaaca ucagacaaca     2100

aaguacaaua cgacguagua uuucauggcg ucuugacaga uaaugccgac auuucaaaua     2160

acaaagcccc aauagcuaaa gugacaggac caucaacagg cgcagucgga agaaauauug     2220

aguucucagg gaaagauagu aaagacgaag auggaaaaau aguuagcuau gacugggacu     2280

ucggagaugg agcaacaucu cgagguaaaa acuccguaca cgcauauaag aaagcuggaa     2340

ccuauaacgu uacauuaaaa guaacugaug auaaaggagc aacugcaaca gaaaguuuua     2400

cuauagaaau caaaaacgaa gauaccacaa caccaauaac aaaagaaaug gaaccaaacg     2460

acgacauaaa agaagcgaau ggacccauag uagaaggagu cacuguuaaa ggagacuuaa     2520

augggagcga cgaugccgac acuuuuuauu ucgacguuaa agaagaugga gacguaacua     2580

uagaauuacc cuacucugga aguaguaauu uuaccuggcu aguauacaaa gaaggcgaug     2640

aucaaaacca uauagcguca ggaauagaua aaaauaauuc aaaagugggc acuuucaaaa     2700

gcacaaaagg aagacauuac guauucauuu auaaacacga uucagcauca aacauaucau     2760

acucgcuuaa uauaaaagga cuaggaaacg aaaaacuuaa agaaaaagaa aacaaugacu     2820

caucagacaa agccacagua auuccaaauu uuaacacuac uaugcaagga agccuuuuag     2880

gagaugauag uagagauuau uauucauucg aaguaaaaga agaaggagaa guuaauaucg     2940

aacuagauaa gaaagaugag uucgguguaa cguggacauu acacccugaa uccaauauua     3000

acgacagaau caccuaugga caaguugacg gaaauaaagu cagcaacaaa guuaaauuaa     3060

gacccggaaa auauuaccuc cuaguuuaua aauauagcgg aucaggaaac uacgaauuac     3120

gaguaaauaa augaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  3618
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt12)

<400>  3618
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

ggguaacauu cauaucauua cuuuuccuau uuucaucagc auacaguaug aagaaaaaua      120

uauuaaaaau auuaauggac agcuauagca aagaaucaaa aauacaaaca guuagaagag      180

uaacuagcgu uagcuuauua gccguauacu uaacaaugaa uacaaguagc cuaguauuag      240

caaaaccgau agaaaauaca aacgacacga gcaucaaaaa cguugaaaaa cuaagaaaug      300

cccccaacga agaaaacagu aagaaagucg aagacaguaa aaaugauaaa guagaacaug      360

ugaaaaacau agaagaagcc aaaguagaac aaguagcccc ugaaguuaaa agcaaaucaa      420

cgcuacgcag cgccaguagg agaagaagaa aaagaauagc aaauacuaac ucagaaaaau      480

augacuucga auacuuaaau ggacuaaguu acacagaacu uaccaaucuu aucaaaaaca      540

uaaaauggaa ucaaauaaau ggacuauuca auuauuccac ugggucacaa aaauuuuucg      600

gagauaaaaa uagagugcag gcuauaauua acgcacuaca agaaucagga agaaccuaca      660

cagcaaacga uaugaaaggg auagaaacuu ucacugaagu acugcgagcg ggauucuauu      720

ugggguacua uaacgacggu uuaucauacu uaaacgacag aaauuuucaa gacaaaugua      780

uaccagcaau gauagcaaua cagaaaaauc cuaauuuuaa acuagggacc gcaguacaag      840

acgaagugau aacaucacuc gguaaacuca uaggaaaugc uucagcuaau gcggaaguag      900

uaaauaauug cguaccaguu uuaaaacaau ucagagaaaa ccucaaccaa uaugcacccg      960

acuauguaaa aggaacugca guuaacgaac uuaucaaagg aaucgaauuu gauuuuagcg     1020

gagccgcgua cgaaaaagac gugaaaacaa ugccuuggua uggaaaaaua gacccauuca     1080

uuaacgaauu aaaagccuua ggccuguacg guaauauaac uucagccaca gaaugggcaa     1140

gugacguugg cauauacuau uugucgaaau uuggauugua uucaacaaac cguaacgaca     1200

uaguucaaag ccuggaaaaa gcaguagaua uguacaaaua uggaaaaaua gccuuuguag     1260

caauggaaag gauuacaugg gauuaugacg gaauaggcuc aaaugguaag aaaguagauc     1320

augauaaguu ucuagacgau gcagaaaaac acuaucuucc aaagacauac accuucgaca     1380

auggaacuuu uauuauaagg gcaggcgaca aaguauccga agagaaaaua aaacguuuau     1440

acugggcauc acgggaagua aaaagccaau uucauagagu aguaggaaac gacaaagcau     1500

uagaaguagg aaacgcagau gacguacuca caaugaaaau auucaauucu ccugaagaau     1560

auaaauucaa uacaaauaua aauggaguca guacagacaa uggaggacua uacauagaac     1620

cuagagggac auuuuauacu uacgaaagaa caccccaaca auccauauuu ucccuagaag     1680

aauuguuccg acaugaauac acacauuauu uacaagcccg auacuuagua gacggauuau     1740

ggggacaagg uccauucuac gagaaaaaca gauugacaug guucgacgaa ggaacagcag     1800

aauuuuucgc cggaucaacu agaaccuccg guguauuacc aagaaaaucc auccuugggu     1860

acuuagcaaa agauaaagua gaucaucguu auucguuaaa gaaaacauua aauagcggcu     1920

acgaugauuc agauuggaug uuuuauaauu auggcuuugc uguagcacau uaucuauacg     1980

aaaaagauau gccaacuuuc aucaaaauga acaaagcgau cuuaaauaca gacguuaaau     2040

cauaugacga aaucauaaag aaauuaucag augaugcaaa uaaaaacaca gaauaucaaa     2100

accacauaca agaacuagcu gauaaauauc agggugcagg aaucccacuc guaucggacg     2160

auuaccuaaa agaccaugga uauaagaaag caagcgaagu auacucagaa auuaguaaag     2220

cugcaucucu uacaaauaca agcguaacgg cagagaaaag ccaauauuuc aacacguuca     2280

cacuacgcgg aacauauacu ggagaaacaa guaaaggaga guucaaagau ugggacgaaa     2340

ugucaaagaa auuagauggu acuuuagaau cauuagccaa aaauagcugg uccggguaca     2400

aaacacuuac cgcauacuuu acaaauuaua gagucacaag cgauaauaaa guucaauacg     2460

augucgucuu ucacggagua cuaacagaca acgcggauau aagcaauaau aaagcaccaa     2520

uagcaaaagu aacaggacca ucaaccggag cuguuggaag aaacauugag uucucaggaa     2580

aagacucaaa agacgaagau ggcaaaauag uaagcuauga uugggauuuu ggagacggcg     2640

caacauccag aggcaaaaau agcguccaug ccuauaagaa agcaggaaca uacaacguaa     2700

cauuaaaagu aacagacgac aaaggagcca ccgccacuga aaguuuuacu aucgaaauca     2760

aaaaugaaga uacaaccacc ccaauaacca aagaaaugga accuaaugau gacauaaaag     2820

aagcuaaugg gccaauugua gaaggaguca cagucaaagg cgacuuaaac gggagcgacg     2880

acgcugauac cuucuacuuu gacguaaaag aagauggaga uguaacaaua gaacuaccau     2940

auucagguuc auccaauuuu acauggcuag uguacaaaga aggugacgac caaaaccaua     3000

uagccagugg aauugacaaa aacaauucua aaguggggac uuuuaaaagc acaaaaggua     3060

gacauuaugu auuuauauac aaacaugaua gugcaagcaa cauaucauac ucucuaaaua     3120

ucaaaggcuu aggaaacgaa aagcuaaagg aaaaggaaaa uaacgauucc ucagauaaag     3180

caacugugau cccaaauuuc aacacuacua ugcaaggcag ccuucucggu gaugauagcc     3240

gagauuacua cuccuuugaa gucaaagaag aaggugaagu caacauagaa uuggauaaga     3300

aagaugaguu cggcgucaca uggacacugc auccagaauc aaacauaaac gauagaauca     3360

ccuacggaca agucgacgga aauaaaguaa gcaauaaagu caaauuaaga ccaggaaaau     3420

acuaccuucu aguauauaaa uacucuggaa guggaaauua cgaauuacga guuaauaaau     3480

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  3619
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt12)

<400>  3619
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uuuugaagau aauacuaaau agaggaaaaa caaugaaaag aaaaugccua uccaaacgau      120

uaaugcuggc cauaacuaug gcaacaauau uuacaguaaa caguacauua ccuauauaug      180

cagcuguaga uaaaaacaac gcuacagcug ccguccagaa cgaaucuaaa agguacaccg      240

uaucuuaucu aaaaacucua aacuacuaug acuuaguaga uuugcuagua aaaacagaaa      300

uagagaaucu accagacuua uuucaauauu caagcgaugc caaagaguuc uauggaaaua      360

aaaccagaau gaguuuuaua auggaugaaa uagguagacg agcaccacaa uacacagaaa      420

ucgaccauaa gggaauaccg acacuuguag aagugguaag agcaggauuc uauuuaggau      480

uccauaauaa agaauuaaac gagauaaaca aacgauccuu uaaagaaaga gucauaccaa      540

gcauauuagc aauccagaaa aauccaaauu ucaagcuagg aacagaagua caagauaaaa      600

uuguaagcgc aacaggauua cucgcaggga acgaaacagc acccccagaa gucgugaaca      660

acuucacccc aauacuccaa gacuguauca aaaauauaga uagauacgca cuagaugacc      720

uaaaaaguaa agcccuuuuc aacguacuug cagcaccaac cuaugauaua acugaauacc      780

uacgagcaac aaaagagaaa ccagaaaaca cacccuggua cgggaaaaua gacggcuuua      840

uaaaugaguu aaagaaauua gccuuauaug guaaaauaaa ugauaauaau ucauggauaa      900

uagacaacgg cauuuaucau aucgcaccuc ugggaaaauu acacaguaau aacaaaauag      960

guauugaaac acuaacagaa guaaugaaag uuuauccaua ucuaagcaug caacaccucc     1020

aaucagcaga ucaaauaaaa cgacacuacg acucuaagga cgcagaaggg aacaaaauac     1080

cacuagacaa auucaagaaa gaaggaaaag aaaaauacug cccaaaaaca uauacauucg     1140

acgauggcaa aguaauuauc aaagcuggcg caaggguaga ggaagaaaaa guaaaacguc     1200

uauauugggc uucaaaagaa guaaauucac aauucuuucg aguuuacgga auugauaaac     1260

cauuagaaga aggaaaccca gaugacauuc uaacuauggu uauauauaau ucaccagaag     1320

aauauaaacu aaacucagua uuauacggau augauaccaa caacgguggg auguacauag     1380

aacccgaagg aacauucuuu acuuaugaac gcgaagcaca agaaagcacu uacacguuag     1440

aagaacuauu ccgacacgaa uauacacauu acuuacaagg acgcuaugca guuccaggac     1500

aauggggacg aacaaaauua uaugauaacg acagacuaac augguacgaa gaaggaggag     1560

cagaauuauu ugcugguagu acucgaacaa guggaauacu acccagaaaa agcauuguaa     1620

gcaacauaca uaauacaaca cgcaacaaca gauauaaacu aucagauacu guacauucca     1680

aauauggcgc cagcuuugag uucuacaacu acgcaugcau guucauggac uacauguaca     1740

auaaagacau ggguauacuc aacaaacuaa acgaucucgc caaaaauaac gacguugacg     1800

gauaugauaa uuacauuaga gaccucaguu caaauuaugc auuaaaugac aaauaccaag     1860

aucacaugca agaaagaaua gauaacuaug aaaacuuaac aguaccauuc guugcagacg     1920

auuacuuagu aagacacgca uauaaaaacc cuaacgaaau auauucggaa auuucagaag     1980

uugcaaaauu aaaagaugca aaaucugaag uaaagaaaag ucaauauuuu ucgaccuuca     2040

cauuacgugg aagcuauaca ggaggugcau ccaaaggaaa acucgaagau caaaaagcaa     2100

ugaacaaauu uauagacgac ucuuuaaaga aacuagacac auauucgugg agcggguaca     2160

aaacauuaac ggcauacuuc acgaauuaua aaguugacag uucaaauaga gucacauaug     2220

auguagucuu ucacggauac cuaccuaacg aaggagacag uaaaaauagu cuccccuaug     2280

ggaaaauaaa uggcacauac aaagguaccg agaaagagaa aauaaaauuu uccucggaag     2340

gcucauucga cccugaugga aaaauaguau cauacgaaug ggacuucgga gauggaaaua     2400

aaaguaacga agaaaaucca gaacacucau acgauaaagu agggaccuau accguaaaac     2460

ucaaaguaac agaugacaaa ggcgaaagcu caguuucaac aacaacugca gaaauuaaag     2520

auuuaucaga aaauaaauua ccaguaauau auaugcaugu accaaaaagu ggggcacuaa     2580

aucaaaaagu aguguucuau gggaaaggaa cauaugaucc agacggauca auugcagguu     2640

accaauggga uuuuggagau gguucagauu ucucaaguga acaaaaucca ucccacguuu     2700

auacaaagaa aggagaauac acaguaacuu uacgaguaau ggacaguuca gggcaaaugu     2760

cggagaaaac aaugaaaauu aaaauaacag auccaguaua cccaauagga acagaaaaag     2820

aaccuaauaa uucaaaagaa acugcaucag ggccaauagu acccggaaua cccguauccg     2880

guacuauaga aaacacauca gaucaagacu acuucuauuu ugauguuaua acgccaggag     2940

aaguaaaaau agauaucaac aagcuaggau auggaggagc aacgugggua guguaugaug     3000

aaaauaauaa cgcaguuuca uaugcaacug acgauggaca aaaccucucc ggaaaauuca     3060

aagcagauaa accaggaagg uauuacauac accuguacau guucaauggc ucuuauaugc     3120

cguaucguau aaauaucgaa gggucaguag gaagauaagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  3620
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt12)

<400>  3620
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaac       60

gaaaaugcuu aucaaaaaga uuaauguuag caauaacaau ggccacuaua uucacuguca      120

auucaacccu uccaauauac gccgcaguag acaagaacaa ugcuacagca gcaguacaaa      180

augaaaguaa gagauacaca guaucguauc uaaaaacucu aaacuauuau gaccucgugg      240

accugcuagu aaaaacagaa auagaaaauu uaccugauuu auuccaguau ucaucagaug      300

caaaagaguu cuauggcaau aagacaagaa uguccuucau aauggaugaa auaggcagac      360

gagcaccaca auacacugaa auugaccaca agggaauacc aacccuaguc gaaguaguca      420

gagcaggauu cuaccuaggc uuccauaaua aggaacuaaa cgaaauaaac aaaagaaguu      480

ucaaagaaag agugauacca ucaauauuag caauacagaa aaaucccaac uuuaaacuug      540

gaacagaagu acaagacaaa auugugagcg caaccggauu acuagcaggg aacgaaacag      600

caccucccga aguagugaau aauuuuacgc caauauuaca agauugcauu aaaaacauag      660

acagauaugc acuagaugau uuaaaaucua aagcauuauu uaacguacua gcagcuccca      720

cauaugauau aacagaauac cucagagcca ccaaagaaaa accugaaaau acaccauggu      780

auggaaaaau cgacggcuuu aucaaugaac uuaaaaagcu agcacuauau ggaaaaauca      840

acgauaacaa cucauggauc auagauaaug gaauauacca uauagcaccc uuaggcaaac      900

uucacucaaa caauaaaauc ggcauagaaa cauuaacgga aguaaugaaa guauacccuu      960

aucuaucuau gcaacauuua caaucagcag aucaaauaaa acgccacuac gauaguaaag     1020

augcagaagg aaacaaaaua ccccucgaca aguucaagaa agaaggaaaa gaaaaauauu     1080

guccaaaaac auauacguuc gacgauggaa aaguaauaau aaaagcagga gcaagaguag     1140

aagaggaaaa aguaaaaaga uuauacuggg cgucaaaaga aguaaacuca caauucuuca     1200

gaguuuaugg aauagacaaa ccauuagagg aaggaaaucc cgaugacauu cuuaccaugg     1260

ugaucuacaa caguccugaa gaauauaaac uaaauucugu ccucuacgga uaugauacaa     1320

acaacggagg cauguauauc gaaccagaag gaaccuuuuu cacauaugag agagaagcuc     1380

aagaaucaac cuacacccuc gaggaacuau ucagacacga auauacgcac uaucuacaag     1440

gcagguacgc aguacccgga caauggggcc guacaaaacu auaugacaac gacagacuaa     1500

cuugguacga agaaggaggg gcugaauuau uugccggauc aacaagaacc ucagggauuc     1560

uuccacgaaa aucgauaguu ucgaauauac acaauacaac cagaaacaau agauauaaau     1620

uaucagauac agugcauucc aaauaugggg cuucauucga guuuuacaau uaugcuugca     1680

uguucaugga uuauauguau aacaaagaca ugggaauacu caacaaacua aaugaccucg     1740

cuaaaaacaa ugacguagau ggauacgaca auuacauacg cgauuuaagc uccaacuaug     1800

cauuaaacga caaauaucaa gaucauaugc aagaaagaau agauaauuau gagaaucuaa     1860

caguaccguu cgucgcagau gauuacuuag ugcggcacgc auauaaaaac ccuaaugaaa     1920

uuuauagcga aauaagugaa guugcaaaau uaaaagacgc aaaaagugaa guaaagaaau     1980

cacaauacuu uagcacauuc acauuaagag gaaguuauac uggaggagcc uccaaaggua     2040

aacuagaaga ccaaaaagcu augaacaaau uuauagauga uagucuuaag aaacuugaca     2100

ccuauucaug gaguggauau aaaacauuaa cagcuuauuu cacuaacuau aaaguagauu     2160

caucaaaucg cguaacuuau gaugucguuu uccacgguua uuuacccaac gaaggagaca     2220

guaaaaacuc acuaccauac gguaaaauaa auggcacuua caaaggaaca gaaaaagaga     2280

aaauaaaauu caguucugaa ggaucauucg acccagaugg aaaaauagug agcuaugaau     2340

gggacuucgg agaugguaau aaaagcaaug aagaaaaucc agaacacagu uaugacaaag     2400

uagguacaua cacuguuaaa uuaaaaguca cagacgauaa aggcgaaagu ucaguaucaa     2460

caacaacagc cgaaauaaaa gaucuaagcg aaaacaaacu acccgucaua uauaugcacg     2520

uaccuaaaag uggagcccuu aaccaaaaag ugguauucua cggaaaagga acauacgacc     2580

cugacggaag cauagcagga uaucaauggg acuucgguga cgguucggac uucucuucug     2640

aacaaaaucc aagccacgua uacacaaaga aaggagaaua caccguaaca cuuagaguua     2700

uggacagcuc aggacaaaug ucagagaaaa caaugaaaau caaaauuacc gacccuguau     2760

auccaauagg aacugaaaaa gaaccaaaua acaguaaaga aacagcuagu ggaccgaucg     2820

uuccagguau uccuguaagu ggaacaaucg aaaacacauc agaccaggac uauuuuuauu     2880

ucgauguaau aacaccagga gaagucaaaa ucgauauaaa uaaacuagga uauggagggg     2940

cuacaugggu aguauacgau gaaaacaaca augcaguauc cuacgcgaca gaugacggac     3000

agaaccuuuc aggaaaauuc aaagcggaca aaccaggcag guacuacaua caccuauaca     3060

uguucaacgg auccuauaug ccuuaucgaa uuaauauaga aggauccgua ggccguuaag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  3621
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt12)

<400>  3621
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

gggugacauu cauaucucua cuuuuccuau ucuccucagc auacucagua caaaacgaau      120

caaaaagaua cacagugagu uacuuaaaaa cguuaaacua cuaugaccua guagaccuuc      180

uaguaaaaac cgaaauagaa aaucuaccag accuauucca auacucuuca gaugccaaag      240

aauuuuaugg aaauaaaacc agaaugaguu ucaucaugga ugaaaucgga aggagagcac      300

cacaauacac ggaaauagau cacaaaggua uacccacuuu aguagaaguc guaagagcag      360

gauucuacuu aggauuccau aacaaagaac ucaaugaaau uaauaaaaga ucuuucaaag      420

aaaggguaau acccagcaua cucgccauac agaaaaaccc caacuucaaa cuaggaacag      480

aaguacaaga uaaaauagua ucagcaacug guuuacucgc uggaaaugaa accgcaccac      540

cagaaguagu aaacaacuuc accccuauuc uacaagacug cauuaaaaau auagacagau      600

acgcccuaga cgacuuaaaa ucgaaggccc ucuuuaacgu acuagccgcc ccaacauaug      660

auauaacaga auacuuaaga gcaaccaaag aaaaaccaga aaauacaccc ugguacggaa      720

aaauagacgg auuuauaaau gaauuaaaga aauuagcguu auaugggaaa auaaacgaca      780

auaauaguug gauaauagac aacggaauau accacauagc accauuaggc aaacuacacu      840

ccaauaacaa aauagggaua gaaaccuuaa cagaaguaau gaaaguauau ccauaucuau      900

caaugcaaca uuugcaauca gcagaccaaa uaaaacgaca uuaugauagu aaagacgcag      960

aaggaaauaa aauaccacua gauaaauuca agaaagaagg aaaagaaaaa uauuguccaa     1020

aaacauacac auucgaugac ggaaaaguaa uaauuaaagc cggugcccgg guagaagaag     1080

aaaaaguaaa acgacuguau ugggcuucua aagaagucaa uucacaauuc uuuaggguau     1140

acggaauuga uaaaccucua gaagaaggua acccagacga cauccuaaca auggucauau     1200

acaauagccc ggaagaauac aaauuaaacu cgguauuaua cggguaugac acaaauaacg     1260

gcggcaugua cauugaaccc gaaggaacgu ucuucacaua ugaaagagaa gcacaagaau     1320

caacauacac acucgaagaa cuauuuagac acgaauauac acauuauuua caagggagau     1380

acgccguacc cggacaaugg ggucgaacca aacuuuacga caacgacagg cuaacauggu     1440

acgaagaagg gggagcagaa uuauucgcag gaucaacaag aaccucagga auacuaccua     1500

gaaaaaguau aguaucaaau auacauaaua caaccaggaa uaacagauau aaauuaagug     1560

acacagucca uucaaaauau ggagccuccu uugaguucua uaacuacgca uguauguuca     1620

uggauuacau guacaacaaa gauaugggaa uccuaaacaa acuaaacgac cuagcuaaaa     1680

auaacgaugu ugacggauac gauaacuaca uaagagaccu cagcucaaac uaugcacuua     1740

acgacaaaua ucaagaucau augcaagaaa gaauagacaa cuacgaaaau cucacaguac     1800

cauucguagc agacgauuau uuaguaagac acgcauacaa gaacccuaac gaaaucuauu     1860

ccgaaauuag cgaaguagcg aaacuuaaag acgcaaaaag ugaaguaaag aaaagucaau     1920

acuucagcac auucacacua cgaggauccu acacaggcgg cgcaagcaaa ggcaaacuag     1980

aagaucaaaa agcaaugaac aaauucauag acgauucacu caagaaauua gauacauaua     2040

gcuggagugg auacaaaaca cuaacugcau auuucacaaa cuacaaaguu gacagcucaa     2100

auagagucac auaugaugua guauuccacg gauaucuacc caaugaaggu gacagcaaaa     2160

acuccuuacc auacggaaaa auuaacggga cauacaaagg aacagaaaaa gagaaaauaa     2220

aauucucauc cgaagguagc uuugaccccg auggaaaaau uguaucauau gaaugggacu     2280

ucggagacgg aaauaaauca aacgaagaaa auccugaaca cagcuaugau aaaguuggca     2340

ccuauaccgu gaaacuaaaa gugacagaug acaaagguga aucauccgua uccacaacga     2400

cagcagaaau uaaagacuua agcgaaaaca aacuaccagu aauauacaug cauguaccaa     2460

aauccggcgc auuaaaucaa aaagucguau uuuauggaaa agggacuuau gaccccgaug     2520

ggucaaucgc aggcuaucaa ugggacuucg gcgauggcuc agacuucuca ucagaacaga     2580

acccaucuca uguuuacaca aagaaaggag aauacacagu aacauuacga gucauggauu     2640

caucagguca aaugucagag aaaacaauga aaauaaaaau aacagauccg guuuacccaa     2700

uaggaacaga aaaagaaccc aacaauucaa aagaaacagc aaguggcccu auaguuccag     2760

guauuccugu aucagguaca aucgaaaaca caucagacca ggauuacuuu uacuucgacg     2820

ugauuacgcc aggagaaguu aaaaucgaua uuaauaaauu aggauauggu ggagccacgu     2880

ggguaguaua cgaugaaaau aauaaugcag uaucauaugc cacagaugac ggacaaaauc     2940

uuucagggaa auuuaaagcu gauaaaccag gaagauauua uauacaccuu uacauguuca     3000

acgguucaua caugccuuac agaauaaaua uagaaggauc cguagguaga uaaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3622
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt12)

<400>  3622
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

gggugacauu caucucacua uuauuucuau ucaguagcgc auauucuaug aaacgaaaau      120

gcuuauccaa aagacuaaug cuagcaauaa caauggcaac aaucuucacc guaaauucaa      180

cauuaccaau cuacgcagcc guagauaaaa acaaugcaac agcagcucga aggagaagga      240

aaaggguaca aaacgaaagc aaaagauaua ccgucagcua ccuuaaaacc uuaaauuacu      300

acgacuuagu agaucucuua guaaaaacag aaauagaaaa cuuacccgau uuguuucaau      360

auucauccga cgcaaaagag uucuacggaa auaaaacaag aaugagcuuc auaauggacg      420

aaauaggucg gagagcuccc caauauaccg aaauagauca uaaaggaaua ccaaccuuag      480

uagaaguagu aagagccgga uuuuaccuug gcuuccauaa caaagaacua aacgaaauaa      540

acaaacgauc cuucaaagag cgcguaauac caaguauacu ggccauccag aaaaacccaa      600

acuuuaaauu aggaacggaa guucaagaca aaauaguaag ugcaacaggg cuccuagcag      660

gaaacgaaac agcucccccu gaaguuguaa auaacuucac accaauacuu caagacugua      720

uuaaaaacau agacagauac gcauuagacg accuuaaaag caaagcguua uuuaacguac      780

uagcugcacc cacuuaugac auaacugaau acuuaagagc aacaaaagaa aaaccagaaa      840

acacaccuug guauggcaaa auagauggau uuauaaauga acuaaagaaa cuggcacuau      900

auggcaaaau caacgauaau aacaguugga uaauagacaa cgguauauau cauauagcac      960

cacuagguaa auugcauuca aacaauaaaa uugguauaga aacguuaaca gaggugauga     1020

aaguauaccc auaccuaucu augcaacauu uacaaucagc ggaucaaauu aaaaggcacu     1080

augauucaaa agaugcggaa gguaacaaaa uaccacuaga caaauucaag aaagaaggaa     1140

aagaaaaaua uugucccaaa acauacacau uugaugaugg uaaaguaaua auaaaagcag     1200

gggcucgagu agaagaagaa aaaguuaaac gacuauacug ggccucaaaa gaagucaacu     1260

cucaauuuuu ccgcguauac ggaaucgaua aaccauuaga agaagguaau ccggaugaua     1320

uauuaaccau ggugaucuac aacucaccag aagaauacaa acuaaauuca guccuauaug     1380

gauacgacac uaauaauggu ggaauguaca uagaaccaga aggcacauuc uucacauacg     1440

aaagagaggc ucaagaauca acauacacac uagaagaauu auuccgacac gaauacacac     1500

auuacuuaca aggaagauac gcgguacccg gacaaugggg aagaacaaaa cuauacgaua     1560

augaucgacu uacaugguau gaagaaggag gagccgaacu auucgcagga uccacgcgca     1620

ccucagggau ucuuccaaga aaaucaauag uaucaaauau acacaauaca acacgaaaua     1680

acagauauaa auuaucagac acaguacacu ccaaauaugg cgcaaguuuc gaguucuaca     1740

auuacgcaug uauguucaug gauuacaugu auaacaaaga uauggggauc uuaaacaaac     1800

uaaacgauuu agcgaaaaac aaugacguag acggcuauga caacuacaua cgagacuuau     1860

ccagcaauua cgcacuuaac gauaaauacc aagaucacau gcaagaaaga auagauaacu     1920

acgaaaaucu aacaguccca uuugucgcag acgacuaccu ggugagacac gcuuacaaaa     1980

auccaaauga aauauacuca gaaauaagcg aaguagcuaa acucaaagac gccaaaagug     2040

aaguuaagaa aagucaauac uuuucaacau ucacccuccg gggaucauau accgggggag     2100

caucuaaagg aaaauuagaa gaccaaaaag ccaugaauaa auuuauagau gacucccuaa     2160

agaaacugga cacuuacucc uggagugggu acaaaacuuu aacagcuuau uucaccaacu     2220

auaaaguaga cagcagcaau cgagucacau augacgucgu guuucauggu uacuuaccaa     2280

acgaaggaga cagcaaaaac ucacuucccu augguaaaau aaacgguaca uacaaaggaa     2340

cagaaaaaga gaaaauuaaa uucucuucug aaggaucauu ugauccagau ggaaaaaucg     2400

ugaguuauga augggacuuu ggagacggaa acaaaucuaa cgaagaaaac ccagaacaca     2460

guuaugauaa aguuggaacc uacacaguaa aacuaaaagu gacugacgau aaaggagaau     2520

caucagucag uacaacuaca gccgaaauaa aagaucuaag cgaaaauaaa cuccccguaa     2580

uauauaugca cgucccaaaa ucaggagccu uaaaucaaaa aguugucuuu uacgguaaag     2640

gaacauacga ucccgaugga ucaaucgcag gauaucaaug ggacuuugga gaugguagcg     2700

auuucuccag cgaacaaaac cccucacacg uauauacaaa gaaaggagag uauacaguaa     2760

cauuaagagu gauggauagc ucgggacaaa ugucagagaa aacaaugaaa auaaaaauua     2820

cggauccagu auaccccaua ggaacagaaa aagaaccaaa caauuccaaa gaaaccgcua     2880

gugguccaau cguacccggc auuccgguga gcgguacuau agagaacaca ucagaccaag     2940

auuacuuuua cuucgacguc auuacaccag gcgaaguaaa aauagauaua aauaaauuag     3000

guuacggagg ugcaacuugg guaguauaug acgagaacaa caacgccguc ucauacgcaa     3060

ccgacgacgg ucaaaaucua ucaggaaaau ucaaagcaga caaaccaggu agauacuaca     3120

uucaccuaua cauguucaau ggaaguuaca ugccauacag aauaaacaua gaaggauccg     3180

uuggaagaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  3623
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt12)

<400>  3623
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu uuucgcaugc cuacucggag cagcauucgc aaugccacua ccaccacacc      120

caggacaccc aggauacaua aacuucucau acgaaguacu aacaccacua aaaugguacc      180

aaucaauaag accaccauac ccaucauacg gauacgaacc aaugggagga ugguuacacc      240

accaaauaau accaguacua ucacaacaac acccacccac acacacauua caaccacacc      300

accacauacc aguaguacca gcacaacaac caguaauacc acaacaacca augaugccag      360

uaccaggaca acacuccaug acaccaauac aacaccacca accaaaccua ccaccaccag      420

cacaacaacc auaccaaccc caaccaguac aaccacaacc acaccaacca augcaaccac      480

aaccaccagu acacccaaug caaccacuac caccacaacc accacuacca ccaauguucc      540

caaugcaacc acuaccacca augcucccag accuaacacu agaagccugg ccaucaacag      600

acaaaacaaa aagagaagaa guagacuaag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  3624
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt12)

<400>  3624
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

uaccuccaca uccaggucac ccuggauaua uaaauuucuc uuacgaagua cuuacaccuc      120

uaaaauggua ucaaucuaua cguccaccuu acccuucaua uggauaugaa ccuaugggug      180

gaugguaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  3625
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt12)

<400>  3625
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaucaaua agaccaccac caaugcuacc agaccuaaca cuagaagcau      180

ggccaucaac agacaaaaca aaaagagaag aaguagacua aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  3626
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt12)

<400>  3626
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacacua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc auacccauca uacggauacg      240

aaccaauggg aggaugguaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  3627
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt12)

<400>  3627
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacacua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc accaaugcua ccagaccuaa      240

cacuagaagc auggccauca acagacaaaa caaaaagaga agaaguagac uaaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  3628
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt12)

<400>  3628
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauccu auucgcuugc cuaguaggag cagcauucgc caugccauua ccaccacacc      120

caggacaccc aggauacaua aacuucucau acgaaguacu aacaccacuc aaaugguacc      180

aaucaaugau aagaccacca uacucaucau acggauacga accaauggga ggauggcuac      240

accaccaaau aauaccagua guaucacaac aacacccauu aacacacaca cuacaaucac      300

accaccacau accaguagua ccagcacaac aaccaagagu aagacaacaa gcacucaugc      360

caguacccgg acaacaauca augacaccaa cacaacacca ccaacccaac cuaccacuac      420

cagcacaaca accauuccaa ccacaaccag uccaaccaca accacaccaa ccaaugcaac      480

cacaaccacc uguacaacca augcaaccac uauuaccaca accaccacuc ccacccaugu      540

ucccacuaag accacuacca ccaauacuac cagaccuaca ccuagaagca uggccagcaa      600

cagacaaaac aaaacaagaa gaagucgacu aaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  3629
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt12)

<400>  3629
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaucaaug auaagaccac cauacucauc auacggauac gaaccaaugg      180

gaggauggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3630
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt12)

<400>  3630
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaucaaug auaagaccac caccaauacu accagaccua caccuagaag      180

cauggccagc aacagacaaa acaaaacaag aagaaguaga cuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3631
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt12)

<400>  3631
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacauua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cauccaggac acccaggaua uauaaauuuc ucauacgaag      180

uauuaacacc acuaaaaugg uaucaaucaa ugauaagacc accauacagc ucauacggau      240

acgaaccaau gggaggaugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3632
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt12)

<400>  3632
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacacua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaucaaucaa ugauaagacc accaccaaua cuaccagacc      240

uacaccuaga agcauggcca gcaacagaca aaacaaaaca agaagaagua gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3633
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt12)

<400>  3633
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

ccuggauauu auucgcaugc cuacuaggag cagcauucuc aaugccacua ccaccacacc      120

caggacaccc aggauacaua aacuucuccu acgaaguauu aacaccacua aaaugguacc      180

aaaacaugau aagacacccc uacacaucau acggauacga accaauggga ggauggcuac      240

accaccaaau aauacccgua guaucacaac aaacaccaca aucacacgca cuacaacccc      300

accaccacau accaauggua ccagcacaac aaccaggaau accacaacaa ccaaugaugc      360

cacuaccagg acaacacuca augacaccaa cacaacacca ucaaccaaac cuaccacuac      420

cagcacaaca accauuccaa ccacaaccag uacaaccaca accacaccaa ccacuacaac      480

cccaaucacc aaugcacccc auacaaccac uacuaccaca accaccacua ccaccaaugu      540

ucucaaugca aucacuacua cccgaccuac cacuagaagc auggccagca acagacaaaa      600

caaaacgcga agaaguagac uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3634
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt12)

<400>  3634
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaaauaug auaagacacc cauacacauc auacggauac gaaccaaugg      180

gaggauggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3635
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt12)

<400>  3635
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaaacaug auaagacacc caucacuacu accagaccua ccacuagaag      180

cauggccagc aacagacaaa acaaaaagag aagaaguaga cuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3636
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt12)

<400>  3636
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacauua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cauccaggac acccaggaua uauaaauuuc ucauacgaag      180

uauuaacacc acuaaaaugg uaucaaaaua ugauaagaca uccauauaca ucauacggau      240

acgaaccaau gggaggaugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3637
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt12)

<400>  3637
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacacua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaaaca ugauaagaca cccaucacua cuaccagacc      240

uaccacuaga agcauggcca gcaacagaca aaacaaaaag agaagaagua gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3638
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt12)

<400>  3638
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauauu auucgcaugc cuacuaggag cagccuucuc aaugccacua ccaccacacc      120

caggacaccc aggauacaua aacuucucau acauaagaca uccauacaca ucauacggau      180

augaaccaau gggaggaugg cuacaccacc aaauaauacc aguaguauca caacaaaccc      240

cacaaucaca cgcacuacaa ccacaccacc acauaccaau gguaccagca caacaaccag      300

gaauaccaca acaaccaaug augccauuac caggacaaca cuccaugaca ccaacacaac      360

accaccaacc aaaccuacca cuaccagcac aacaaccauu ccaaccacaa ccaguacaac      420

cacaaccaca ccaaccacua caaccacaau caccaaugca cccaauacaa ccacuacuac      480

cccaaccacc acuaccacca auguucucaa ugcaaucacu acuaccagac cuaccacuag      540

aagcauggcc agccacagac aaaacaaaac gagaagaagu agacuaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  3639
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt12)

<400>  3639
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauauu cuucgcaugc uuacuaggag cauccuuagc aaugccacua ccaccacacc      120

caggccaccc aggauacaua aacuucucau acgaaguacu aacaccacua aaaugguacc      180

aaaacaugau aagacaccca uacacaucau acggcuacga accaaugggc ggcuggcuac      240

accaccaaau uauaccagua guaucacaac aaacaccaca aucacacgca cuacaacccc      300

accaccacau accaauggua ccagcacaac aacccggaau accacaacaa ccaaugaugc      360

cacucccagg acaacacuca augacaccaa cacaacacca ccaaccaaac cucccacuac      420

cagcacaaca accauuccaa ccccaaccag uacaaccaca accacaccaa ccacuacaac      480

cacaaucacc uaugcaccca auacaaccau uacuacccca accaccacua ccaccaaugu      540

ucucaaugca aucacuacua ccagaccuac cacuagaagc auggccagca acagacaaaa      600

caaaaagaga agaagucgac uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3640
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt12)

<400>  3640
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu auucgcaugc cuacuaggag cagcauucuc aaugccacua ccaccacacc      120

caggacaccc aggauacaua aacuucucau acgaaguacu aacaccacua aaaugguauc      180

aaaacaugau aagacaccca ucacuauuac cagaccuacc acuagaagca uggccagcaa      240

cagacaaaac aaaaagagaa gaaguagauu aaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  3641
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt12)

<400>  3641
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu auucgcaugc cuacuaggcg cagcauucuc aaugccacua ccaccacacc      120

ccggacaccc aggcuacaua aacuucucau acgaagauuu auacuuagaa gcaauaagaa      180

uagacagaac agcauuugua uuaacaccac uaaaauggua ccaaaacaug auaagacacc      240

cauacacauc auauggauac gaacccaugg gaggauggcu acaccaccaa auaaucccag      300

uaguaucaca acaaacacca caaucacacg cccuacaacc acaccaccac auaccaaugg      360

uaccagcaca acaaccagga auaccacaac aacccaugau gccacuacca ggacaacacu      420

caaugacacc aacacaacac caccaaccca accuaccacu accagcacaa caaccauucc      480

aaccacaacc aguacaacca caaccacacc aaccauuaca accacaauca ccaaugcacc      540

caauacaacc ccuacuacca caaccaccac uaccaccaau guucucaaug caaucacuac      600

uaccagaccu accacuagaa gccuggccag caacagacaa aacaaaaaga gaagaaguag      660

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  3642
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt12)

<400>  3642
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu auucgcaugc cuacuaggag cagcauucuc aaugccacuc ccaccacacc      120

caggacaccc aggauacaua aacuucucau acgaaguacu aacaccacua aaaugguacc      180

aaaacaugau aagacaccca acaccacaau cacacgcacu ccaaccacac caccacauac      240

caaugguacc agcacaacaa cccggaauac cacaacaacc aaugaugcca cuaccaggac      300

aacacuccau gacaccaaca caacaccacc aaccaaaccu cccacuacca gcacaacaac      360

cauuccaacc acaaccagua caaccacaac cacaccaacc acuacaacca caaucaccca      420

ugcacccaau acaaccacua cucccacaac caccacuacc accaauguuc ucaaugcaau      480

cacuacuacc agaccuccca cucgaagcau ggccagcaac agacaaaaca aaaagagaag      540

aaguagacua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  3643
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt12)

<400>  3643
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

ucccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cucacacccc      120

uaaaauggua ccaaaacaug auaagacacc ccuacacauc auacggauac gaacccaugg      180

gaggauggcu acaccaccaa auaauaccag uagucucaca acaaacacca caaucacacg      240

cacuccaacc acaccaccac aucccaaugg uaccagcaca acaaccagga auaccacaac      300

aaccaaugau gccacuacca ggacaacacu caaugacacc aacacaacac caccaaccaa      360

accuaccacu acccgcccaa caaccauucc aaccccaacc aguacaacca caaccacacc      420

aaccacucca accacaauca ccaaugcacc caauacaacc acuacuacca caaccaccac      480

ucccaccaau guucucaaug caaucacuac ucccagaccu accacuagaa gcauggccag      540

caacagacaa aacaaaaaga gaagaaguag acuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  3644
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt12)

<400>  3644
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccug       60

ggguugcaag acuaccguua cuauugggau uacuacuauu accaaggcca ggaagaccau      120

uagauuuagc agauuauacg uaugauuuag cagaagaaga cgauagugaa ccauuaaauu      180

auaaagaucc auguaaagca gccgcguuuu uaggggacau agcacuagau gaagaagauc      240

uaagagcauu ucaaguacaa caagcaguug accuaagaag acacacagcu agaaaaucau      300

caauuaaagc cgcugucccg ggaaauacga guacaccgag uugucaaucu acuaacggac      360

agccacaacg uggugcaugc ggaagaugga gaggacgcuc aaggagucgg agagcggcaa      420

caagcagacc agaaaggguc uggccagaug gaguaauacc uuucguaaua ggaggaaauu      480

uuacaggaag ucaaagagca guauuccguc aagcuaugag acauugggaa aaacauaccu      540

guguaacguu uuuagaaaga acagaugaag auaguuacau aguguuuacg uaucgaccau      600

gcggauguug uucuuacgua ggaagacgag gggguggucc ccaagcaaua ucaauaggua      660

aaaacugcga uaaauucggg auaguaguac augaacuagg gcauguaguu ggauuuuggc      720

augaacacac acgacccgau agagauagac augucucaau aguaagggaa aacauacaac      780

ccggacaaga auauaauuuc uuaaaaaugg aaccacaaga aguugaaagu uuaggugaaa      840

cguaugacuu cgauaguauu augcauuaug cacgaaauac cuuuaguaga ggaauuuuuc      900

uugacacuau aguaccgaaa uaugaaguaa augguguaaa accaccaaua ggucaaagaa      960

caagauuauc aaaaggagau auagcacaag cucgaaaacu guacaaaugc ccagcuugug     1020

gugaaacauu gcaagauuca acaggaaauu ucaguagccc agaauaccca aacggauaua     1080

gugcgcauau gcauugcguc uggaggauua guguaacacc aggugagaaa auaauacuaa     1140

auuuuacgag uuuagacuua uaucgaagca gauuauguug guaugacuau guugaaguua     1200

gagauggauu uuggagaaaa gcaccauuaa gaggaagauu uuguggauca aaacuaccag     1260

aaccaauagu aaguacagau aguaggcuuu ggguagaguu cagaagcucg aguaauuggg     1320

uaggcaaagg auucuuugca gucuaugaag ccauaugugg aggggauguu aagaaagacu     1380

auggacacau acaaucaccu aauuauccgg acgauuaccg accaagcaaa guuuguauuu     1440

ggcggauuca aguaagcgaa gguuuccacg uaggacuuac auuccaaucu uuugaaauug     1500

aacgccauga uaguugcgca uacgacuauc uagaaguaag agauggucau agcgaaaguu     1560

caacacuaau uggaagauac ugcggauaug aaaaaccuga cgauauaaaa ucaacaagca     1620

gucgauuaug gcuaaaauuu gugagugacg gaagcauaaa uaaagcuggc uucgcuguaa     1680

acuuuuucaa agaaguagau gaauguagua gaccaaauag gggcggaugu gaacaacguu     1740

guuuaaauac uuuaggcucg uauaaaugca gcugugaucc cggauaugaa cucgcaccag     1800

auaaaagaag augugaagca gcauguggag gauuuuugac aaaacuuaau gguuccauaa     1860

ccaguccagg guggccaaaa gaauauccgc caaauaaaaa uugcauuugg cagcuaguag     1920

cuccaacuca auaccguauc aguuuacaau ucgacuucuu ugaaacagaa ggcaaugacg     1980

uaugcaaaua cgauuuugua gaaguuagau cugggcuaac cgcugacagu aaauuacaug     2040

gaaaauuuug uggcucagaa aaaccagaag uaaucacauc acaauacaau aacaugagag     2100

ucgaguuuaa aagcgauaac acaguuagua agaaagguuu uaaagcccau uucuuuagug     2160

auaaagauga augcucaaaa gauaauggag ggugucaaca agauugcgua aauacauuug     2220

gaagcuacga augccaaugu agauccggau uuguacucca ugauaauaaa cacgauugua     2280

aagaagcagg augugaccac aaaguaaccu cuacaucggg gacuaucacg aguccaaacu     2340

ggccagauaa auacccuuca aagaaagaau gcacuugggc gaucaguucu acuccaggac     2400

auaggguuaa auuaacauuu auggaaaugg acauagaauc acaaccugaa ugugcuuaug     2460

accauuuaga aguuuuugau ggaagagaug cuaaagcgcc uguuuuaggu cgguuuugcg     2520

gaaguaaaaa gccugaaccu gucuuagcca cuggcucaag gauguuuuua agguuuuauu     2580

cagacaacuc aguccaaaga aaaggauuuc aagcaaguca ugcgacagaa ugcggaggcc     2640

aaguacgagc agauguaaaa acaaaagauc uuuauucuca ugcacaauuu ggugauaaua     2700

auuauccugg aggaguugau ugugaguggg uaauaguagc agaagaaggu uauggaguug     2760

aauuaguauu ucaaacguuu gaaguagaag aagaaaccga uugcgguuau gacuacaugg     2820

aacuauucga ugguuaugau ucaacagcuc cuagauuagg aagauauugu gggucaggcc     2880

cgccagagga aguauauagu gcaggagaua gcguucuagu aaaauuucac agcgacgaca     2940

caauaaccaa gaaaggauuc caucuacgcu auacaucaac uaaauuccaa gauacacuac     3000

auagcagaaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  3645
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt12)

<400>  3645
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucg       60

caggaacaag augucuacua gcacuauuac uuccacaagu ucuacuagga ggagcagcug      120

gauuaguacc agaauuagga agaagaaaau uugcggcagc aucaucugga agacccaguu      180

cacaaccauc agacgaagua uuaucagaau uugaacuuag acuacuuagc auguucggau      240

uaaaacaacg ucccacacca ucuagagaug caguaguacc acccuauaug cuugaccuau      300

acagacguca cagcggccaa ccaggaucac cagcaccaga ccauagacua gaaagagccg      360

caucaagagc aaacacagua agaucauucc accaugaaga aagcuuagaa gaauuaccag      420

aaacaucagg uaaaacuaca agaagguuuu ucuuuaacuu aagcucuaua ccaacagaag      480

aauuuauaac aucagcagaa uuacaaguau ucagagaaca aaugcaagac gcacuaggca      540

auaauagcag cuuucaccac agaauaaaua uauaugaaau uauaaaacca gcaacagcaa      600

acucaaaauu uccaguaaca agacuauuag acacacgacu aguaaaucaa aaugcaucaa      660

gaugggaauc cuucgacgua acaccagcag uaaugagaug gacagcacaa ggacacgcaa      720

accauggauu uguaguagaa guagcucacu uagaagaaaa acaaggagua aguaaacguc      780

auguaagaau uagcagaagu uuacaucaag acgaacauuc cuggucucaa auuagaccac      840

uacuaguaac auucggacau gacggaaaag gacacccacu acacaaaaga gaaaaacgac      900

aagcaaaaca uaaacaacgu aaaagauuaa aauccucaug uaaaagacau ccauuauacg      960

uagauuucuc agacguagga uggaacgacu ggauaguagc accacccgga uaccacgcuu     1020

ucuauugcca uggagaaugc ccauucccac uugcagacca ucuaaacagc acaaaucacg     1080

ccauuguaca aacauuagua aacagcguaa acuccaaaau accaaaagca ugcugcguuc     1140

caacagaauu aagcgcaaua ucaauguuau acuuagacga aaaugaaaaa guaguacuaa     1200

aaaauuacca agacauggua guagaaggcu guggaugccg cuaaggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  3646
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt12)

<400>  3646
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauac       60

caggaaauag aaugcuuaug guaguauuac uaugccaagu auuacuagga ggugcauccc      120

augccucauu aauaccagaa accggcaaaa aaaaaguagc ugaaauacaa ggacaugcag      180

gaggaagaag auccggacaa ucacacgagc uacuaagaga cuuugaagcu acauuauuac      240

aaauguuugg auuacgaaga agaccacaac cuucaaaauc agcugucauu ccagauuaua      300

ugagagacuu auauagauua caaucuggug aagaagaaga agaacaaauc cacucaacug      360

gacuggaaua uccagaaaga ccagcuucaa gagcuaauac uguucguuca uuucaucacg      420

aagaacauuu agaaaacaua ccaggaacaa gcgaaaauag ugcauuuaga uucuuauuca      480

accuauccag cauuccagaa aacgaaguaa uaucaagugc agaauuaaga uuauuucgug      540

aacaaguaga ucaaggacca gacugggaaa gaggauuuca cagaauuaac auauaugaag      600

uuaugaaacc accugcagaa gucguaccag gucaccuaau aacaagauua uuagauacaa      660

gacuaguaca ucauaacguc acaagauggg aaacuuuuga cguaucacca gcaguauuac      720

gauggacacg agaaaaacaa ccaaauuacg gucuagcaau agaaguaaca caccuacauc      780

aaacaagaac ccaccaagga caacauguac gaauaucaag aucauuacca caaggaagcg      840

gaaacugggc acaauuaaga ccacuacuag uuacuuuugg acacgaugga agaggacacg      900

cacuaacacg gagaagaaga gcaaaacguu caccaaaaca ccauucucaa agagcaagaa      960

aaaaaaauaa aaacugcaga cgacauagcu uauauguaga uuucucagau guagggugga     1020

augacuggau aguagcaccu ccaggauacc aagcauuuua cugucacggu gacuguccau     1080

uucccuuagc cgaucacuua aacucaacaa aucaugcaau aguacaaaca cuaguaaaca     1140

guguaaacuc aaguauaccu aaagcaugcu gcguaccaac agaacuauca gcaauuucaa     1200

uguuauaccu agacgaauau gacaaaguug uauuaaaaaa uuaucaagaa augguuguag     1260

aaggaugugg auguagauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  3647
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt12)

<400>  3647
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

gacuagguag aagggcccaa uggcuauguu gguggugggg ucuauuaugu ucauguugug      120

gacccccucc ucuaagacca ccauuaccag cugcugcagc agcagcagcc ggcgggcaau      180

uacuaggaga uggaggcucg ccaggaagaa cagaacaacc accaccauca ccacaaucau      240

caucagguuu ccuauacaga cgacuuaaaa cacaagaaaa acgagaaaug caaaaagaaa      300

uauuaucugu uuuaggucua ccacauagac cuagaccacu acauggccua caacaaccuc      360

aaccuccagc ccuucgccaa caagaagaac aacaacaaca acaacaauua ccaagaggug      420

agccaccacc cgguagauua aaaucagcuc cuuuauucau guuagauuua uacaacgccc      480

uauccgccga uaaugaugaa gauggagcau cagaaggcga gaggcaacaa ucauggccgc      540

augaagcagc uucaucauca caacgccgac aaccaccucc uggugcugca cauccauuaa      600

aucguaaaag ccuacuugca ccaggaucag gaucuggagg agccucacca cuaacaagcg      660

cacaagauuc agcauuucua aaugacgcug auauggucau gaguuuugua aaucuaguag      720

aauacgauaa agaguucucu ccaagacaaa gacaucauaa agaauuuaaa uuuaaucuau      780

cucaaauccc agaaggagaa guaguaacag cggcagaauu uagaauauau aaagauugug      840

uaaugggauc auucaaaaau caaacuuuuc uaauuucaau auaccaagua uuacaagaac      900

aucaacaucg cgacucagac cucuuuuuac ucgacacccg aguuguuugg gcauccgaag      960

aaggcuggcu agaauuugau auuacagcaa caucaaauuu auggguagua accccucaac     1020

auaacauggg uuuacaauua aguguaguaa caagagacgg aguucacguc cacccaagag     1080

cugcaggauu aguaggaaga gauggaccau augacaaaca accauucaug guugcauucu     1140

uuaaaguuag ugaaguucau guacgaacaa caagaucagc aaguucaaga agaagacaac     1200

aaucuagaaa ccgaaguaca caaucacaag auguugcacg aguaucaucu gccagugacu     1260

auaauucauc agaauuaaaa acagcaugua gaaaacacga auuauacgua ucauuucaag     1320

auuuagguug gcaagacugg auaauagcac caaaaggaua cgcagcaaau uauugugacg     1380

gcgaauguuc auuuccuuua aaugcacaua ugaaugcaac aaaccaugca auaguccaaa     1440

cauuagucca cuuaaugaau ccagaauacg uaccaaaacc uuguugugcc ccaacaaaau     1500

uaaaugcaau cucaguacua uacuucgaug auaauucaaa uguaauauua aagaaauacc     1560

gaaauauggu aguaagagcu ugcggcuguc acuaaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  3648
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt12)

<400>  3648
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaug       60

ucagaucacu uagagcagca gccccacauu cuuucguagc auuaugggca ccauuauucu      120

uauuaagaag cgcacuagca gacuuuucau uagacaauga aguacauagu agcuuuauac      180

auagacgccu aagaucacaa gaaagacgag aaaugcaaag agaaauccua ucaauauuag      240

gauuaccaca uagaccaaga ccucaucuac aaggaaaaca caacuccgcu ccaauguuca      300

uguuagaccu auauaacgca auggcugucg aagaaggagg agguccagga ggacaagguu      360

uuaguuaucc cuacaaagca guauuuagca cacaaggccc accacucgca agcuuacaag      420

auucccauuu ccuaacagau gccgauaugg uuaugaguuu cguuaaucuu guagaacacg      480

auaaagaauu cuuccacccu agauaucacc aucgagaguu cagauucgau cuuucaaaaa      540

uaccagaagg agaagccguu accgcagcag aauuuagaau auauaaagau uacauccgcg      600

aacgauuuga caaugaaaca uucagaauau caguauauca aguacuacaa gaacaucuag      660

ggagagaauc agaucuauuu uuauuagacu cuagaacacu augggcauca gaagaaggau      720

gguuaguuuu cgauauaaca gccacaagca aucacugggu aguaaacccu agacacaacu      780

uaggauuaca auuaagcgua gaaacacucg acggccaaag uauaaacccc aaacuagcag      840

gacuaauagg acgacacggc ccacaaaaca aacaaccauu uauggucgcc uuuuucaaag      900

cuacagaagu acauuuccga ucaauacgau cuacaggauc caaacaaaga ucacaaaaca      960

gaucuaaaac accaaaaaau caagaagcau uaagaauggc caauguagca gaaaauagcu     1020

caucagauca acgacaagca ugcaaaaaac augaacuaua cgugaguuuc agagaucucg     1080

gauggcaaga uuggauaaua gcaccagaag gauaugcagc cuauuauugu gaaggugaau     1140

gugcauuucc acuaaauucu uacaugaaug caaccaauca cgcaauaguu caaacacuag     1200

uacacuuuau aaacccagaa acaguaccaa aaccuuguug cgcaccaaca caauuaaacg     1260

caaucucagu auuauacuuc gaugauaguu cuaacguaau auuaaaaaaa uacagaaaca     1320

ugguagucag agcaugcggu ugucacuaag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  3649
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt12)

<400>  3649
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaag       60

caucagcagc acuacuaugc cuacuacuaa cagcagcagc auucucacca caaggacuag      120

cacaaccagu aggaauaaac acaucaacaa caugcugcua cagauucaua aacaaaaaaa      180

uaccaaaaca aagacuagaa ucauacagaa gaacaacauc aucacacugc ccaagagaag      240

caguaauauu caaaacaaaa cuagacaaag aaauaugcgc agacccaaca caaaaauggg      300

uacaagacuu caugaaacac cuagacaaaa aaacacaaac accaaaacua uaaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  3650
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt12)

<400>  3650
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcuac       60

ucacguugau aauauuauua ccaguaguau caaaauucuc uuuuguuagc cuaagugccc      120

cacaacauug gucuugucca gaagggacgu uagccgggaa uggaaacagu acaugugugg      180

gaccugcccc auuuuuaaua uuuucacacg gaaauuccau cuuuagaauc gauacugaag      240

ggacaaauua ugaacaauua guuguagaug ccgguguauc aguaaucaug gacuuccauu      300

auaaugaaaa acggauuuac uggguugauc ucgaaagaca acuacuucaa agaguguuuu      360

uaaaugggag uaggcaagaa agagucugua auauugagaa aaauguauca ggaauggcua      420

uaaauuggau aaacgaagag guaauauggu cuaaucaaca agaagguauu auaacuguga      480

cugauaugaa aggaaauaac ucacauaucc uccuaucugc ucuaaaauau ccugcuaacg      540

uggcaguuga uccagucgaa cgauuuaucu uuuggucauc agaggucgca ggaucgcuau      600

auagagcaga cuuagauggu guaggaguaa aagcauuacu agaaaccagc gagaaaauaa      660

cugcaguaag uuuagaugua cucgacaaaa gauuauucug gauacaauac aauagagaag      720

gaucaaauuc acuaauaugu ucuugugacu augauggcgg aagcguccac auaucuaaac      780

accccacaca acauaauuua uuugcgauga guuuauuugg ugauagaaua uuuuauagua      840

cguggaaaau gaaaaccaua uggauagcua auaaacauac aggaaaagac augguccgaa      900

uaaaccuaca cucauccuuu guaccucuag gggaauugaa aguaguacau ccacuagcac      960

aaccaaaagc ggaagacgac acaugggaac cggaacaaaa acucuguaaa cucagaaagg     1020

guaauuguuc gaguacugua uguggacaag aucuacaaag ccauuuaugu augugcgcag     1080

aaggauaugc uuuaucaaga gaucgaaaau auugcgaaga ugucaaugag ugugcauuuu     1140

ggaaucaugg auguacccuu ggcugcaaaa auaccccagg cucauauuau ugcacuuguc     1200

caguaggauu uguauuguua ccugauggaa agcgauguca ucaacuugua aguuguccac     1260

gaaauguuag ugaauguuca caugauugcg uguuaacauc agaaggccca uuaugcuucu     1320

gcccagaagg aucaguguua gaaagagaug gcaaaacuug caguggaugc aguagcccag     1380

acaauggugg auguagucaa uuauguguuc cguuaucccc agugucgugg gaaugugacu     1440

guuuuccagg auaugauuua cagcuagacg aaaaaucuug cgcagcaagc gguccacaac     1500

ccuuuuuacu auuugcaaau ucccaagaca uucgucacau gcauuuugau gguacugauu     1560

augguacauu auuaucacaa caaaugggua ugguauaugc auuagaccau gauccugucg     1620

aaaacaaaau auauuucgcu cauacagccu uaaaguggau cgaacgcgcu aacauggaug     1680

gaagucaaag agaaaggcuc auugaagaag gagucgaugu acccgaaggc uuagcaguag     1740

acuggauagg ccgccgauuu uauuggacag auagagguaa aagucuuaua ggacguucag     1800

acuuaaaugg aaaaagaagu aaaauuauaa caaaagaaaa cauaucacaa ccuaggggaa     1860

uagcaguaca uccaauggca aaacgccucu uuuggacaga uacaggcaua aauccuagaa     1920

uugaaaguuc uagcuuacag ggacuaggcc ggcuaguaau ugccucauca gaccuaauau     1980

ggccaagugg gauaaccaua gauuuucuca cggacaaauu guauuggugc gaugcaaaac     2040

agucaguaau agaaauggcu aaucucgaug guucaaagag aaggagauua acacagaacg     2100

auguugguca cccauucgca guagcaguau ucgaggauua cgucugguuu ucggauuggg     2160

caaugccaag uguaaugaga guaaacaaaa gaacagguaa agauagagua cgauuacaag     2220

gauccauguu aaagcccucc ucauuaguag ucguucaucc auuggcuaaa ccaggagccg     2280

acccaugcuu auaccaaaau ggugguugug aacacauuug uaagaaaaga uuaggaacag     2340

ccugguguuc augcagagaa ggcuucauga aagcaucaga uggaaaaaca ugccuagcau     2400

uagauggaca ccaacuacua gcaggaggag aaguugaccu caaaaaccaa guaacgcccu     2460

uagauauauu aaguaaaacu cgaguuagug aggacaacau aacagaaagu caacacaugu     2520

uaguggcuga aauaauggua agugaucaag acgauugugc accaguagga uguucaaugu     2580

augcacgcug uaucucagaa ggcgaagaug caacuugcca augccuaaaa ggcuucgcgg     2640

gcgauggaaa acuauguuca gacauagaug aaugugaaau ggguguuccu guaugucccc     2700

cagcguccuc aaaaugcaua aauaccgaag gcggcuaugu augucguugu ucagaagggu     2760

accaagguga uggaauccau uguuuagaua uagacgaaug ucaauuaggc gaacauaguu     2820

guggugagaa cgcuucuugc accaacacag aaggagguua cacauguaug ugcgcaggga     2880

ggcuaaguga gccaggauua auuuguccag auaguacacc accuccccac cuaagagagg     2940

augaucauca uuacucagua agaaauucag auagugaaug uccauuaucu cacgaugguu     3000

acugccuaca ugacggugua ugcauguaua uagaagccuu agauaaauau gcuuguaacu     3060

guguagucgg cuacauagga gaaagguguc aauauaggga ccuaaaaugg ugggaauuac     3120

gacaugcugg ccaugggcaa caacaaaaag uaauaguugu agcagucugu gucguaguuc     3180

uaguaaugcu ccucuuacua ucccuauggg gugcucauua uuaccgaacg caaaaacuuc     3240

ugaguaaaaa uccuaaaaau ccauacgaag aaucaucaag agauguacga ucaaggagac     3300

cagccgauac agaagauggg augucgucuu gcccacagcc augguucguu guaauaaaag     3360

aacaccaaga uuugaaaaac ggaggucaac cugucgcagg agaggaugga caagcugcag     3420

augguaguau gcaacccaca aguuggagac aagaacccca auuaugcgga augggaacgg     3480

aacaagggug cuggauucca guaucgagcg acaaaggguc uugcccccaa guaauggaaa     3540

gaucguucca uaugcccuca uacggaacgc aaacuuuaga aggaggagua gagaaaccac     3600

auuccuuacu aagcgcaaau ccauuauggc aacaacgagc uuuagaucca ccacaucaaa     3660

uggaauugac acaauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  3651
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt12)

<400>  3651
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugacag       60

caggaagaag aauggaaaug cuaugugcag gaagaguacc agcacuauua cuaugucuag      120

gauuccaucu auuacaagca guauuaagua caacaguaau accaagcugu auaccaggag      180

aaagcucaga caauugcaca gcauuaguac aaacagaaga caauccaaga guagcacaag      240

uaagcauaac aaaaugcuca agugauauga auggauauug cuuacacgga caauguauau      300

aucuaguaga caugagccaa aacuauugca gaugcgaagu aggauacacg ggaguaagau      360

gugaacacuu cuuucuaaca guacaucaac cacuaucaaa agaauacgua gcauuaacag      420

uaauauuaau aauacuauuu cuaauaacag uaguaggaag cacauacuau uucuguagau      480

gguacagaaa cagaaaauca aaagaaccaa aaaaagaaua ugaaagagua acaucaggag      540

auccagaacu accacaagua uaaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  3652
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt12)

<400>  3652
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

aaggagaaau aacaacauuc acagcacuaa cagaaaaauu caaccuacca ccaggaaacu      120

acaaaaaacc aaaacuacua uacugcucaa acggaggaca cuucuuaaga auacuaccag      180

acggaaccgu agacggaaca agagacagau cagaccaaca cauacaacua caauuaucag      240

cagaaucagu aggagaagua uacauaaaau ccacagaaac aggacaauac uuagcaaugg      300

acacagacgg acuacuauac ggaucacaaa caccaaacga agaaugccua uuccuagaaa      360

gacuagaaga aaaccacuac aacacauaca uaucaaaaaa acacgcagaa aaaaacuggu      420

ucguaggacu aaaaaaaaac ggaucaugca aaagaggacc aagaacacac uacggacaaa      480

aagcaauacu auuccuaccc cuaccaguau ccucagacua aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  3653
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt12)

<400>  3653
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguag       60

gggugggagg aggagacgua gaagacguaa caccaagacc aggaggaugu caaauaagug      120

gaagaggagc aagagguugu aauggaauac caggagcggc agcaugggaa gcagcauuac      180

cgagaagaag accgagaaga cacccaagug uaaauccuag aucaagagca gcuggaagcc      240

caagaacacg aggaagaaga acagaagaaa ggccuagugg aaguagauua ggggacagag      300

gaagaggaag agcauugcca ggaggaagac uaggcggaag aggaagagga agagcaccag      360

aaagaguagg agguagagga agaggaagag gaacagcagc accaagagca gcaccagcag      420

caaggggaag uagaccagga ccagcgggaa caauggcagc aggaaguaua acaacacuuc      480

cagcauugcc agaagaugga ggaaguggcg cauuuccgcc aggacauuuu aaagauccaa      540

agagauuaua cuguaaaaau ggagguuuuu uuuuaagaau acauccagau ggaagaguag      600

auggaguaag agaaaaaagu gauccacaua uaaaauuaca auuacaagca gaagaaagag      660

gaguaguaag uauaaaagga guaugugcaa acagauauuu agcaaugaaa gaagauggaa      720

gauuacuagc aaguaaaugu guaacagaug aauguuuuuu cuuugaaaga uuagaaagua      780

auaauuauaa uacguaccga aguagaaaau auacaaguug guauguagcg uuaaaaagaa      840

caggacaaua uaaauuagga agcaaaacag gaccgggaca aaaagcaaua uuauuuuuac      900

cuaugagugc gaaaaguuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  3654
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt12)

<400>  3654
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aauggauacu aacauggaua cuaccaacac uacuauacag aagcugcuuc cacauaauau      120

gcuuaguagg aacaauaagc cuagcaugua acgauaugac accagaacaa auggcaacaa      180

auguaaacug cagcucaccc gaaagacaca caagaucaua cgacuacaug gaaggcggag      240

acauaagagu aagaagacua uucugcagaa cacaauggua cuuacgaaua gacaaaagag      300

gaaaaguaaa aggaacacaa gaaaugaaaa acaacuacaa cauaauggaa auaagaacag      360

uagcaguagg aauaguagca auaaaaggag uagaaucaga auucuaccua gcaaugaaca      420

aagaaggaaa acuauacgca aaaaaagaau gcaacgaaga cugcaacuuc aaagaauuaa      480

uacuagaaaa ccacuauaac acauacgcaa gcgcaaaaug gacacacaac ggaggagaaa      540

uguucgucgc acuaaaccaa aaaggaauac caguaagagg aaaaaaaaca aaaaaagaac      600

aaaaaacagc acacuuccua ccaauggcaa uaacauaagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  3655
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt12)

<400>  3655
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaac       60

uacuaccaag cguaguacua aaacuauucu uagcagcagu acuaagcgca cuaguaacag      120

gagaaagccu cgaaagacua cgaagaggcc uagccgcagg uacaucaaac ccagacccac      180

caacaguauc aacagaccaa uuacuaccac uaggaggagg aagagacaga aaaguaagag      240

accuucaaga agcagaccua gaucuacuaa gaguuacauu aucaucaaaa ccacaagcac      300

uagcaacacc aaacaaagaa gaacacggaa aaagaaaaaa aaaaggaaaa ggacuaggca      360

aaaaaagaga cccaugcuua agaaaauaca aagacuucug cauacacgga gaaugcaaau      420

acguaaaaga acuaagagca ccaucaugca uaugccaccc aggauaucac ggagaaagau      480

gccacggauu aagccuacca guagaaaaua gacuauacac auacgaccac acaacaauac      540

uagcaguagu agcaguagua cuaucaucag uaugucuacu aguaauagua ggacuauuaa      600

uguucagaua ccacagaaga ggcggauacg acguagaaaa cgaagaaaaa guaaaacuag      660

gaaugacaaa uucacacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  3656
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt12)

<400>  3656
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

uuacaaaacu auuacccgcc uuacuauuac agcaugucuu acuacaucua uuacuauuac      120

ccauagcuau accauaugcu gaaggccaac guaaaagaag aaauacaauu caugaauuua      180

aaaaaucagc uaaaacaaca uuaauaaaaa uagacccagc uuugaaaaua aaaacaaaaa      240

aaguaaacac cgcagaucaa ugugcaaauc gauguacacg aaacaaagga uuacccuuua      300

cauguaaagc auuuguauuu gauaaagcca gaaaacaaug cuugugguuu ccuuucaacu      360

caaugucauc aggaguaaaa aaagaauuug gccacgaauu cgaucuauau gaaaauaaag      420

auuauauaag aaauuguaua auaggaaaag gacgaucaua uaaaggaaca guaaguauaa      480

caaaaagcgg aauaaaaugu caaccguggu ccaguaugau accacaugaa cauucauuuu      540

uaccaucauc auaccgaggu aaagacuuac aagaaaauua cugcagaaau ccacgaggag      600

aagaaggagg accauggugc uucacaucaa auccagaagu ucgauaugaa guaugugaca      660

uuccucaaug uucagaagua gaaugcauga cuuguaaugg agaaucuuau agagguuuaa      720

uggaccauac agaaagugga aaaauaugcc aacgauggga ucaccaaaca ccacauagac      780

acaaauuccu accagaaaga uacccagaca aaggauuuga ugauaacuac uguaggaacc      840

cggauggaca accaaggcca uggugcuaua cauuagaucc acauaccaga ugggaauauu      900

gugcaauaaa aacuugugca gauaauacaa ugaaugacac cgauguacca cuugaaacca      960

cagaauguau acaaggucaa ggagaaggau aucgaggaac aguaaauaca auauggaaug     1020

gaauaccgug ucaacgaugg gauagucaau acccccauga acaugacaug acaccagaaa     1080

auuuuaaaug caaagaucua agggaaaauu auuguaggaa uccagaugga ucagaaucac     1140

cuugguguuu caccacagau ccaaauauac gcguuggaua uuguucacaa auaccaaauu     1200

gcgacaugag ucacggacag gauugcuaua gagguaaugg aaaaaauuau augggaaacc     1260

uaucacaaac aagaucaggu cuaacaugcu caauguggga caaaaacaug gaagauuuac     1320

auaggcacau cuucugggaa ccagaugcaa gcaaauuaaa ugaaaauuau ugucgaaauc     1380

cagaugacga cgcacaugga ccaugguguu acacaggaaa cccacuaaua ccaugggacu     1440

auugccccau aucaagaugc gaaggagaua cuacacccac uauaguaaau cuagaucacc     1500

cuguaauauc augugcaaag accaaacaac ucaggguagu aaacggcaua ccaacucgaa     1560

ccaauauugg auggaugguu ucacuaagau accgcaacaa gcauauaugc ggaggaagcc     1620

uaauuaaaga aucaugggua uugacagcaa gacaauguuu cccaagccga gaccuuaaag     1680

auuaugaagc augguuagga auacacgacg uacauggcag aggagaugaa aaaugcaaac     1740

aaguacuuaa cguuucucaa uuagucuacg gaccagaagg auccgacuua guacuaauga     1800

aauuagcaag accagcaguu cuagaugauu uuguaucuac aauagaucua ccaaacuacg     1860

gauguacaau accugaaaaa acaagcugca guguauacgg augggguuau acuggccuua     1920

uaaauuauga cggacuccua aggguagcuc auuuauauau aaugggaaau gaaaaaugcu     1980

cccaacauca ucguggaaaa guuacacuaa augaaucaga aauaugcgca ggugcagaaa     2040

aaauagguuc aggaccaugu gagggagauu augguggacc auuaguuugu gaacaacaua     2100

aaaugcgaau gguccuagga guaauuguac caggaagagg augcgcaaua ccuaauagac     2160

ccggaauuuu cgucagagua gcauacuaug cuaaauggau acauaaaaua auacuaacgu     2220

auaaagugcc ucaaucauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  3657
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt12)

<400>  3657
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcaa       60

aagcagcagc cauaggaaua gaucuuggua caacauauuc augcguaggc guauuucaac      120

auggaaaagu agaaauaaua gcaaacgacc aaggcaaccg aacaacacca uccuacgugg      180

cuuucacaga cacagaaaga cuaauuggcg augcagcuaa aaaucaaguu gcauuaaauc      240

cacaaaacac aguauuugac gcaaaaagac ucauaggaag aaaauuuggg gauccuguag      300

uccaaagcga uaugaaacac uggcccuuuc aaguaauaaa cgacggcgac aaaccaaagg      360

uacagguaag uuauaaggga gaaacaaaag cauuuuaccc cgaagaaauc agcagcaugg      420

uauuaacuaa aaugaaagaa auagccgagg cauauuuagg auauccaguu acaaacgcag      480

ucauaacugu accagcauac uuuaaugauu cacaaaggca agcaacaaaa gaugcaggag      540

uaauagcugg auuaaacgua uuaagaauaa uaaacgaacc aacagcagca gcaauagcgu      600

augguuuaga ccgaacaggc aaaggagaga gaaacguacu aaucuuugau cuaggaggag      660

gaacauucga uguaucaaua uuaacaaucg augacggaau auucgaaguu aaagcaacug      720

caggagacac acacuuagga ggagaagauu uugauaacag auuaguaaac cacuuuguag      780

aagaauuuaa acgaaaacau aagaaagaca uuucacaaaa uaaaagggcu guaagaagac      840

uaagaacagc uugcgaaaga gcuaaaagaa cacuaagcag cucaacacaa gcaagucuag      900

aaauagacag uuuauuugaa ggaaucgauu ucuacacauc aauaacaaga gcacgauuug      960

aagaacuaug uagugaccua uuuagaagca cucuagagcc ugucgaaaaa gcauuaagag     1020

augcuaaauu agacaaagca caaauacacg aucuaguucu aguaggagga ucaacucgaa     1080

uccccaaagu acaaaaacua uuacaagauu ucuucaaugg uagagaccuc aauaaaagua     1140

uuaauccaga ugaagcaguc gcauauggug cugcaguaca ggccgcaauu uuaauggggg     1200

auaaauccga aaacguccaa gaucuauuau uauuagacgu agcaccauua ucacuagguu     1260

uagaaacagc uggaggggua augacugcau uaauaaaaag gaacaguaca auaccgacaa     1320

aacaaacaca aauauuuaca acauacucag auaaucaacc aggaguuuua auucaaguau     1380

acgagggaga acgcgcaaug acaaaagaca acaaucucuu aggccgguuu gaacuaucag     1440

guauaccucc agccccuaga gguguuccac aaauagaagu aacauuugau auugacgcua     1500

augguauccu aaacgucaca gcaacugaca aaucaaccgg aaaagcaaau aaaaucacaa     1560

uaacaaauga uaagggaaga cuuaguaaag aagaaaucga aagaauggua caagaggcag     1620

aaaaauauaa agcggaagac gaaguacaaa gagaaagagu aagugcuaaa aacgcgcuug     1680

aauccuaugc auucaauaug aaaucagcag ucgaggacga aggauuaaaa ggaaaaauaa     1740

gugaagcaga caaaaagaaa guuuuagaua aaugccaaga aguuauuuca ugguuagaug     1800

caaauacauu agcagaaaaa gacgaguucg aacauaaaag gaaagaacua gaacaaguau     1860

guaauccuau aauaagcgga uuauaccaag gugcgggagg uccaggaccc ggugguuucg     1920

gugcucaagg accuaaaggc ggcaguggaa guggaccaac uauagaagaa guagauuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3658
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt12)

<400>  3658
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcua       60

aagcagcagc aaucggaauc gauuuaggga caacauacag cuguguagga guauuccaac      120

acggaaaagu ugaaauaaua gcaaaugauc agggaaacag gacaacuccu agcuauguug      180

cauuuaccga uaccgaacgu cucauuggag augcggcaaa aaaucaggua gcauuaaacc      240

cccaaaacac aguauuugac gcuaaaagau uaauaggacg aaaauucgga gauccgguug      300

uacaaagcga caugaaacac uggccauuuc aaguaauaaa ugauggagac aaaccaaaag      360

uccaagucuc uuacaaagga gaaacaaaag cauucuaccc agaagaaaua ucaaguaugg      420

ucuuaaccaa aaugaaagaa auagcagaag cauacuuagg guacccagua acaaaugcag      480

uaauaacagu ucccgcauau uuuaacgaua gccaaagaca agcuacuaaa gacgcaggag      540

uaaucgcagg auuaaaugua cuuagaauua uaaaugagcc aacugcagca gcaauugcau      600

auggauugga caggacugga aaaggagaaa gaaacguauu aauauuugac cuaggaggag      660

gcacauuuga cguaucaaua uuaaccauag acgacggaau auucgaggua aaagcaacag      720

caggagacac ccauuuagga ggagaagauu ucgauaaucg auuaguaaau cauuuuguag      780

aagaauuuaa aagaaaacau aaaaaagaua uaucacaaaa uaaaagagca guuagacgau      840

uacgaacagc uugcgaaaga gcaaaaagaa cccuaaguuc uagcacacaa gcuagccuug      900

aaauugauuc ccuauuugaa ggcauagauu ucuauacaag caucacucga gcaagauuug      960

aagaauuaug cagugacuua uuuagaucaa cucuagaacc uguagaaaaa gcgcuuagag     1020

acgccaaauu agauaaagca caaauccaug auuuagucuu aguaggagga ucaaccagaa     1080

uacccaaagu acaaaaacua uuacaagacu ucuucaacgg aagagaucua aauaaaucaa     1140

uaaauccuga cgaggcaguu gccuacggag ccgcgguaca agcagcaaua cuaaugggag     1200

acaaaagcga aaacguacaa gaucuauuac uucuagaugu agcaccucua aguuuaggau     1260

uagaaacagc aggaggagua augaccgcac uaauaaaaag gaauucaacg auaccaacaa     1320

aacaaacuca aauuuucaca acauacucag acaaucaacc uggaguacua auacaaguau     1380

acgaaggaga gagagcaaug acaaaagaua acaaucuauu gggaagauuc gaacuaucag     1440

gaauaccccc ggcgccacga ggaguaccgc aaauugaagu aacuuuugau auagaugcca     1500

auggaauauu aaauguaacc gcaaccgaua aaagcacugg aaaagcaaau aaaauaacaa     1560

uaacaaauga caaaggaaga cuaucaaaag aagaaauaga acgaaugguc caagaagcag     1620

aaaaauacaa agcagaagac gaaguacaac gagaacgagu uucagccaaa aaugcauuag     1680

aaucauacgc auuuaacaug aaaagugcag uagaagacga aggacuaaaa ggaaaaaucu     1740

cagaagcaga uaaaaaaaaa guacuggaua aaugucaaga agucauaagu ugguuagacg     1800

caaauacauu agcagaaaaa gacgaauucg aacacaaaag aaaagagcua gaacaagucu     1860

guaacccuau aauaagugga cuauaccaag gagcgggagg accaggacca ggagguuuug     1920

gugcacaagg uccaaaaggc ggaagcggca gcggaccuac aauagaagaa guagauuagg     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3659
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt12)

<400>  3659
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcua       60

cagcaaaagg aauagcuauu ggaauagauc uaggcacaac auacaguugc guuggcguuu      120

uucagcaugg aaaaguagaa auuauagcaa augaucaagg aaaucgcacc acuccuucuu      180

auguagcuuu cacagauaca gaacgacuua uaggagacgc ugcuaaaaac caaguugcaa      240

ugaacccaca aaauacuguc uuugacgcaa aaagacuaau aggccgaaaa uucaaugacc      300

caguaguaca agcggacaug aaacuuuggc cauuccaagu gaucaacgaa ggugguaaac      360

caaaaguauu aguaucauac aaaggagaaa auaaagcauu uuacccagaa gaaauaagcu      420

cuaugguacu gacuaaauua aaagaaacag cagaagcauu ucuaggacac ccaguaacaa      480

augcaguaau aacaguaccc gcuuacuuua augacuccca aagacaagca acaaaggacg      540

caggaguuau agcaggacuu aauguacuua gaauaaucaa cgaaccaaca gcggcagcaa      600

uagccuaugg auuagauaaa ggaggacaag gagaacgaca uguauuaaua uuugaccuag      660

guggagguac auucgauguc ucuauauuaa ccauagacga cggaauauuc gaaguaaaag      720

caacagcagg ggacacucau uuaggcggag aagauuuuga caauagauua guaagccacu      780

ucguagaaga guucaaaaga aaacacaaaa aggauauaag ucagaauaaa cgagcaguaa      840

gaagacuacg aacagccugu gaaagagcua aaagaacguu aucaaguuca acacaagcaa      900

aucuagaaau agacagucua uaugaaggaa uagauuucua uaccucaaua acgagagcua      960

gauuugaaga acuaugcgca gaucuauuca gaggcacacu agaaccagua gaaaaagcuc     1020

uacgagaugc aaaaauggac aaagcuaaaa uucaugauau aguccuugua gggggaucaa     1080

caagaauacc aaaaguacaa agauuguuac aagauuacuu uaacggaaga gauuuaaaca     1140

aaucaauaaa cccagaugaa gcuguagcau auggcgcagc aguacaagca gcaauacuua     1200

ugggagauaa aagugaaaaa guacaagauu uauuauuauu agacguagca ccacuauccc     1260

uaggacuaga aacagcagga ggaguaauga cagcacucau aaaaagaaau aguaccauac     1320

caacaaaaca aacccaaaua uuuacaacgu auagcgacaa ucaaccagga guacuaauac     1380

aaguguauga aggagaaaga gcaaugacca aagauaauaa ucuucuuggc cgauucgauc     1440

ucacaggaau accuccagca ccaagaggag ucccacaaau ugaaguuaca uuugacauag     1500

acgccaaugg uauacuaaac guaacagcua ccgauaaaag uacaggaaaa guaaacaaaa     1560

ucacaaucac aaaugacaaa gguagauuau caaaagagga aaucgaaaga augguauugg     1620

acgcagaaaa auauaaagca gaagacgaag uacaaagaga gaaaauagca gcuaaaaacg     1680

cucuugaauc auaugcauuu aacaugaaau caguaguauc cgacgaagga cucaaaggaa     1740

aaauaagcga aucagauaaa aauaaaauac ucgauaaaug caacgaacua uuaagcuggu     1800

uagaaguaaa ucaacuagca gaaaaagaug aauuugacca uaaaagaaaa gaacuagaac     1860

aaauguguaa uccaauaaua acuaaauuau accaaggagg augcacagga ccagccugug     1920

gcacaggaua uguuccugga cgacccgcaa cuggaccaac aauagaagaa guugauuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3660
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt12)

<400>  3660
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

caagaggacc agcgauugga aucgaucuag gaacaacgua caguugcgug ggaguauucc      120

aacauggaaa aguugaaaua aucgcaaaug aucagggaaa uagaacuaca ccaucauacg      180

uugcuuuuac agacaccgaa agauugauug gagacgcagc gaaaaaucaa guagcaauga      240

auccaaccaa cacaaucuuu gacgcaaaaa gacucauagg cagaaaauuc gaagacgcaa      300

cgguacagag cgauaugaaa cacuggccau uuagaguagu aucagaagga ggaaaaccaa      360

aaguacaagu cgaauauaaa ggagaaacua aaacauuuuu cccagaagaa auaagcagua      420

ugguauuaac aaaaaugaaa gaaauagcag aagcauaucu aggaggaaaa guucauagug      480

caguaauaac uguaccagca uauuuuaaug auucacaaag acaagccacg aaagaugccg      540

gaacaauaac cggauuaaau guacugagaa uaauaaacga accaacagcu gccgcaauag      600

cauacgggcu agauaagaaa ggaugugccg gaggugagaa aaauguauua auauuugacu      660

uaggcggagg aacauuugau guaucaauac uaacaauuga agacggaaua uucgaaguua      720

aaaguacggc gggagauaca cauuuaggag gagaagauuu ugauaacaga augguaaguc      780

auuuagcaga agaguucaaa cgaaaacaca agaaagacau aggaccuaau aaaagagcag      840

uaagaagacu aaggacugca ugcgaaagag caaaaagaac acuaaguagc aguacacagg      900

cgaguauaga aauagacuca uuauaugaag gagucgauuu uuauacuuca auaacgagag      960

caagauucga agaacucaau gcggauuuau uuagaggaac auuggaacca guagaaaaag     1020

cacuuagaga ugcaaaacua gacaaaggac aaauccaaga aauaguccua guagguggcu     1080

caacaagaau accaaaaauc caaaaacuau ugcaagauuu cuucaauggc aaagaauuaa     1140

auaagucaau caauccagac gaagcagucg cauacggagc agcaguucaa gcagcaauau     1200

ugauagggga uaaaucagaa aauguacaag accuauuauu guuagaugua acaccauuaa     1260

gucucgguau agaaacugca ggaggaguaa ugacaccucu aauaaaaaga aacacaacua     1320

uaccaacaaa acaaacacaa acauuuacaa cauacaguga caaucaauca aguguauuag     1380

uacaaguaua cgaaggagaa agagcaauga cgaaagacaa caaucuauua ggaaaauuug     1440

aucuaacagg gauuccucca gcaccgagag guguaccaca aaucgaagua acauuugaca     1500

uagacgcaaa uggaauauua aacguaacag cagcagauaa aucaaccggg aaagaaaaca     1560

aaaucacaau aacuaacgau aaagggaggu uaagcaaaga ugauaucgau cguauggucc     1620

aagaagcaga aagauauaaa agcgaggaug aggcaaacag agacagagua gcagcgaaaa     1680

augcauuaga aucuuacacg uauaauauaa aacaaacugu agaggacgaa aaauuacggg     1740

gaaaaauauc cgaacaagau aaaaacaaaa uauuagauaa augccaagaa gucauaaacu     1800

gguuagacag aaaucaaaug gcagaaaaag augaauacga acauaaacag aaagaacuag     1860

aaagagugug uaaucccaua auaucaaaau uauaccaagg agguccagga gguggaagcg     1920

ggggaggagg aaguggcgca agcggagggc caacaauaga agaaguagau uagggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  3661
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt12)

<400>  3661
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucug       60

uaguaggaau agaccucgga uuucaaaguu guuauguagc agucgcucgg gcaggaggca      120

uugaaacaau ugcaaaugaa uacucagaca gguguacacc agcaugcaua aguuucggac      180

caaaaaaccg aucaauaggc gcagcagcaa aaagccaggu aauaucaaau gcuaaaaaua      240

caguacaagg guuuaaaaga uuccacggaa gagcauuuuc agauccuuuu guagaagcug      300

aaaaaaguaa uuuagccuac gacauaguuc aguuaccaac aggauuaaca ggcauaaaag      360

uaacuuauau ggaagaagaa cgaaacuuua caacugaaca aguaacagca augcuacuau      420

cuaaauuaaa agaaacugca gaaaguguuu uaaaaaaacc aguaguagac uguguaguaa      480

gcgugccaug uuuuuauaca gacgcggaaa gaagaucggu cauggaugca acacaaauag      540

cagggcucaa uugccuuagg cucaugaaug aaacaacugc aguagcucua gcuuacggaa      600

uuuauaaaca agacuugcca gcacuagaag agaaaccaag aaacgucguu uucgucgaua      660

ugggacacuc agcauaccaa guaaguguuu gcgcauuuaa uagaggaaaa cuaaaaguau      720

uggcaacagc auuugacaca acacuaggag guagaaaauu cgaugaagua cuagucaauc      780

acuuuuguga agaauucgga aaaaaguaca aacuagauau uaaaucaaaa auuagagcau      840

uauugcgacu aagccaagaa ugugaaaaac uaaaaaaauu aaugucagca aaugcaucug      900

acuuaccauu aagcauugaa ugcuuuauga augauguaga ugucucagga acaaugaauc      960

gaggaaaauu cuuagaaaug uguaacgauc uacuagcuag agucgaaccc ccucucaggu     1020

cagugcuaga acaaacaaaa cuaaaaaaag aagauauaua cgccguggaa aucguaggug     1080

gagcuaccag aauaccagcu gugaaagaga aaauaaguaa auucuucggc aaagaauuau     1140

caacaacacu aaaugcagac gaagcaguua cccgaggaug ugcuuuacaa ugugcaauuu     1200

uaucgccagc auucaaagua cgagaauucu caauaacaga uguaguaccu uaucccauau     1260

cucuuagaug gaauucacca gcagaagagg gaagcucaga uugcgaagua uuuucaaaaa     1320

accacgcugc accguuuucc aaaguacuga cuuucuacag aaaagaacca uuuacguuag     1380

aagcauacua uucaucuccc caagacuuac cauacccaga ucccgccauu gcacaauucu     1440

caguacaaaa ggugacccca caauccgacg gauccagcuc aaaagugaaa guaaagguaa     1500

gaguaaaugu acacggcaua uuuucaguaa guucagcguc ccucguagaa guucacaaaa     1560

gcgaagaaaa cgaagaacca auggaaacag accaaaacgc aaaagaagaa gaaaaaaugc     1620

aaguagacca agaagaaccc cauguagaag aacaacaaca acaaacaccc gcagaaaaca     1680

aagccgaaag ugaagaaaug gaaacaucac aagcaggcag uaaagauaag aaaauggauc     1740

aaccaccaca ggcaaaaaaa gcuaaaguaa aaacaaguac aguagaucuc ccaauugaaa     1800

aucaacuacu auggcaaauc gauagagaga uguuaaaccu auacaucgaa aaugaaggaa     1860

aaaugaucau gcaagacaaa cuagaaaaag aacggaacga ugcaaaaaac gcaguggaag     1920

aguauguaua ugaaaugcga gacaaacuau caggagaaua ugaaaaauuu guuagcgagg     1980

augacagaaa uucauucacc uuaaaacuag aagauacuga aaauugguua uaugaagacg     2040

gagaagacca accuaagcaa guguacguug auaagcuagc agagcucaaa aauuugggcc     2100

agccaauaaa aauaagauuc caagaauccg aagaaagacc gaaacuauuc gaagaacuug     2160

ggaaacaaau acagcaauac augaagauaa ucucaucauu uaaaaacaaa gaagaucaau     2220

acgaccacuu agacgcagca gacaugacua aaguagaaaa aucuacgaac gaagcaaugg     2280

aauggaugaa uaacaaacua aaucuucaaa acaaacaauc acuuacaaug gacccaguag     2340

uaaaaagcaa agaaaucgaa gcgaaaauaa aagaauuaac gagcacaugu ucaccuauaa     2400

uaucaaaacc aaaaccaaaa guggaaccac cuaaagaaga acaaaaaaau gcagaacaaa     2460

auggaccggu agacgggcaa ggagacaauc caggaccuca agcagccgaa cagggcacag     2520

acacagcagu accaucagac agcgacaaaa aacuaccgga aauggacaua gacugaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  3662
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt12)

<400>  3662
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagug       60

ugguaggaau agaccuugga uuccuaaauu gcuacauagc uguagcaaga ucaggaggca      120

uugaaacaau agcaaacgaa uauagcgacc gaugcacacc agcaugcaua ucauuaggaa      180

guaggacuag agccauaggu aaugcggcaa aaucacaaau aguaaccaau guaagaaaca      240

ccauacaugg auucaagaaa cuacacggac gcagcuucga cgauccaaua guacaaacag      300

aaagaauuag acuacccuac gaacuacaga aaaugccaaa cggaucugca ggagucaaag      360

uaagauaccu ugaagaagaa cggccauuug caauugaaca agugacagga auguuacuug      420

caaaacuaaa agaaacaagu gaaaaugcau uaaagaaacc aguagcagau ugcguaauuu      480

caauacccag cuucuucaca gacgcagaaa gaagaagugu aauggcagca gcacaaguag      540

ccggacuaaa cugucuaaga cuaaugaacg aaacaacagc uguagcuuua gcauacggca      600

uauauaaaca agaucuacca ccacuagaug aaaaaccaag aaacguaguu uuuauagaua      660

ugggacacuc agccuaccaa guccuaguau gugcuuucaa caaaggaaaa uuaaaaguac      720

uugcaacaac auuugaucca uaucuagggg guagaaauuu cgacgaagcu cuaguagacu      780

acuuuuguga ugaguucaaa acaaaauaca aaauuaaugu caaagaaaau ucaagagcau      840

uacucagacu uuaccaagaa ugcgaaaaau uaaagaaacu aaugucugca aaugcauccg      900

auuuaccgcu aaauaucgaa ugcuuuauga augaucuuga cguaucaagc aaaaugaaca      960

gagcacaauu ugaacaacua ugugcauccu uauuagcaag aguagaaccu ccccuaaaag     1020

cgguaaugga acaagcuaau cuccaacgcg aagacauaag cucaauagaa auaguaggcg     1080

gagcaaccag aauaccggca gugaaagaac aaauaacaaa auuuuucuua aaagacauuu     1140

cuacaacuuu aaacgcagac gaagcugugg cuagagguug cgcacuucaa ugcgccaucu     1200

uaucaccagc guucaaaguc cgcgaguuca guauaacaga ccugguacca uacaguauca     1260

cgcuccgaug gaaaacuagc uuugaagacg gcucugggga augcgaagua uucuguaaaa     1320

aucacccagc accauuuagc aaaguaauaa cauuucacaa gaaagaacca uucgaacuag     1380

aagcauucua cacaaacuua caugaaguuc ccuacccaga ugcacgaaua gguaguuuca     1440

caauacaaaa uguauuccca caauccgacg gagacucauc uaaagucaaa gucaaagugc     1500

ggguaaacau acauggaaua uucuccguug caagugcaag ugugauagaa aaacaaaacc     1560

ucgaagggga ucauucagac gcaccuaugg aaacggaaac aaguuucaaa aacgaaaaca     1620

aagauaauau ggacaaaaug caaguagauc aagaagaagg acaccaaaaa ugccaugcgg     1680

aacauacucc cgaagaagaa auagaucaua caggugcuaa aacaaaauca gcaguauccg     1740

acaaacaaga caggcuaaau caaacacuca agaaaggaaa aguaaaaagu auagaccugc     1800

cgauacaaag cagucucugu cgacaauuag gacaagauuu acuaaauagu uacauagaaa     1860

augaagggaa aaugauuaug caagauaaau uagaaaaaga aaggaacgau gccaaaaaug     1920

cuguugaaga auacguauau gacuuucgcg acagauuagg aacaguauac gaaaaauuua     1980

uaacccccga agaccuaagu aaacuaucug caguacuaga agacacagaa aauugguuau     2040

augaagaugg agaagaucag ccaaaacaag uuuacguaga uaaacuacaa gagcuuaaga     2100

aauacggaca accaauucaa augaaauaua uggaacauga agaacgcccg aaagcauuaa     2160

acgacuuagg aaagaaaaua caauuaguaa ugaaaguaau agaggccuac agaaacaaag     2220

augaaaggua ugaccaccuc gaucccacag aaauggaaaa aguugaaaaa ugcauaucag     2280

acgcuauguc auggcuaaac agcaaaauga acgcccaaaa caaauuauca cuuacucagg     2340

auccuguagu aaaaguaagc gaaauaguag cgaaaagcaa agaacuagac aacuuuugua     2400

acccuauaau cuauaaaccu aaacccaaag cagaaguacc agaggauaaa cccaaagcca     2460

auucugaaca uaaugggcca auggauggac aauccggcac agaaacaaaa ucggacagua     2520

ccaaagacuc aucacagcac acaaaaagca guggagaaau ggaaguugac uaaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  3663
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt12)

<400>  3663
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaac       60

ucucacuagu agcagcgaug uuauuacuuu uaagugcugc acgagcagag gaagaagaua      120

aaaaagaaga cguagguaca guaguaggua uagaccuagg aacaacauac ucauguguag      180

gaguauucaa gaauggacga guagaaauua uagcaaauga ucaaggcaau agaauaacac      240

caaguuaugu agcuuucaca cccgaaggag aaagauuaau aggggacgca gcuaaaaacc      300

aauuaacaag caauccagag aacacaguau uugacgcaaa aagauuaauc ggcagaacau      360

ggaaugaccc cucuguacaa caagauauua aauuucuacc guuuaaagug guagaaaaaa      420

aaacaaaacc uuauauacaa guagacauag gaggaggaca aacgaaaaca uucgcuccag      480

aagaaauaag cgcaaugguu uuaacuaaaa ugaaagaaac agcggaagca uauuuaggaa      540

aaaaaguaac ucacgcugua guaacagucc cagcauacuu uaacgaugcu caaagacaag      600

ccacaaaaga ugcaggaaca auugcaggcu uaaauguaau gagaauaaua aaugaaccua      660

cagcagccgc aauagcguac ggacuagaca aaagagaagg cgaaaaaaac auacuaguau      720

uugauuuagg aggaggaaca uucgauguaa gucuacuuac aauugacaac ggagucuuug      780

aaguaguagc cacaaaugga gauacgcauc uaggaggaga ggacuucgac caaaggguua      840

uggaacacuu cauaaaauua uacaaaaaaa aaacaggaaa agacguuaga aaagacaaua      900

gagccguaca aaaauuaaga cgagagguag aaaaagcaaa aagagcauug ucaagccaac      960

accaagcaag aauagaaaua gaaucauuuu augaaggaga ggacuucagc gaaacacuua     1020

caagagcaaa auuugaagaa cugaauaugg auuuauuuag aaguacaaug aaaccaguuc     1080

aaaaagucuu agaagauagu gauuuaaaaa aaagcgacau agaugaaaua guacucguag     1140

gaggaucaac aaggauacca aaaauacaac aauuaguuaa agaguuuuuu aauggaaaag     1200

aaccaucacg aggaauaaau ccagacgaag caguagcaua cggagcagca guacaggcag     1260

gaguacuaag cggagaucaa gauacaggag aucuagucuu acuagauguc ugcccacuua     1320

cauuaggaau cgaaaccgua ggagggguaa ugacaaaacu aauaccacgu aacacgguug     1380

ugccaacaaa aaaaucacag auauucagua cagcgucaga caaucagcca accgucacua     1440

uaaaaguaua cgaaggagaa cgaccacuua caaaagauaa ccaucuacua ggaaccuucg     1500

auuuaacagg aauaccaccc gccccaagag gaguaccaca aauagaaguu acauucgaaa     1560

uagacguaaa cgguauucuu agagugacag cugaagacaa aggaaccgga aauaaaaaua     1620

aaauaacaau aacuaacgau caaaaccgac uaacuccaga agaaauagaa cgcaugguaa     1680

acgaugcaga aaaauuugca gaagaagaca aaaaacuaaa agaacgaauc gauacuagaa     1740

augaacuaga aucauacgca uauucauuaa aaaaucaaau aggcgacaaa gaaaaacuag     1800

gaggaaaauu aucaagugag gauaaagaaa cuauggaaaa agcggucgaa gaaaaaauag     1860

agugguuaga aagucaucaa gacgcugaua uagaagauuu uaaagcaaaa aaaaaagaau     1920

uagaagagau aguacaacca auaauaucaa aacuauaugg aagcgccggu ccuccaccaa     1980

caggcgaaga agacacagcu gaaaaagacg aauuaugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  3664
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt12)

<400>  3664
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

ccccaagaga auuagcaguu ggaauagacc uagguacaac auacucaugu guaggaguuu      120

uucaacaagg aagaguugag auacuagcaa augaucaagg aaacagaaca acacccagcu      180

auguagcauu cacugacaca gaaagauuag ucggagacgc cgcaaaauca caagcagcuc      240

uaaacccuca uaauacaguu uuugaugcua aaaggcuuau agggagaaaa uucgcagaca      300

caacaguaca aucagauaug aaacacuggc ccuuucgagu aguaucagaa ggaggaaaac      360

cgaaaguaag aguuugcuau agaggagaag auaaaacauu uuacccagaa gaaaucucau      420

caaugguucu uaguaagaug aaagagacag cggaagcaua cuuaggacaa ccggucaaac      480

acgccguuau aacaguaccu gcauauuuca augacaguca aagacaagcu acaaaagaug      540

caggagcaau agcaggauua aauguauuaa gaauuauuaa ugaaccaaca gccgcagcaa      600

uagcauacgg acuagaucgu agaggagccg gagaaagaaa cgucuuaaua uuugauuuag      660

gagggggaac auuugaugua ucaguucuau cgauagaugc aggaguauuu gaaguaaaag      720

cuacagcagg agauacacau uuaggcgggg aagauuuuga uaacagauua guaaaucacu      780

ucauggaaga auuuagaaga aaacacggua aggacuuauc aggaaauaaa cgagcacuca      840

gaagacuuag aacagccugu gaacgagcaa aacguacuuu gagcucaagu acacaagcua      900

cuuuagaaau agacaguuua uucgaaggug uugauuuuua cacaaguauu acuagagcaa      960

gauuugaaga acuauguuca gauuuauuuc guucaacauu agaaccagua gaaaaagcac     1020

uaagagaugc aaaacuagau aaagcucaaa uacaugaugu ggugcuagua ggagguucca     1080

caaggauccc aaaaguccaa aaacuacuac aagauuucuu uaauggcaaa gaacucaaca     1140

aaaguauaaa ucccgaugaa gcaguagcau auggugcagc aguacaagca gcaguuuuaa     1200

ugggagauaa gugugaaaaa guacaagauu uacuauuacu agacguagca ccccuaucac     1260

ucggacuaga aacagcugga ggaguaauga cuacacuaau ucaaagaaac gccacaaucc     1320

caacaaaaca aacacaaaca uuuacaacau acucagauaa ucaaccaggc guauuuauac     1380

agguuuacga aggugaacga gcaaugacca aagacaauaa ucuacucggu agauucgaac     1440

uaaguggaau accaccagcc ccaagaggag uaccacaaau agaaguaaca uuugauauag     1500

augcaaaugg uauucucagc guaacugcaa ccgaccguag cacaggaaaa gcuaacaaaa     1560

uaacuauaac gaaugauaaa ggaagacuaa guaaagaaga aguagaacgc augguacaug     1620

aagcagaaca auauaaagca gaagacgaag cacaaagaga uagaguugca gcuaaaaaca     1680

guuuagaagc acauguguuc cauguaaaag gaucauuaca agaagaauca uuaagagaua     1740

aaauuccaga agaagauaga cgaaaaaugc aagauaaaug cagagaagua cucgcauggc     1800

uagagcacaa ucaauuagca gagaaagagg aauaugaaca ccagaaacga gaauuagaac     1860

aaauuugucg accaauauuu aguagguuau acggaggacc aggaguccca ggagguucau     1920

cauguggaac ccaagcaaga caaggagauc ccaguacagg uccaauaaua gaagaaguug     1980

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  3665
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt12)

<400>  3665
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

cuccaagaga acuagcugua ggaauagauu uaggaacaac auauaguugu guaggaguau      120

uucaacaagg aagaguugaa auacuagcaa augaucaagg gaauaggaca acaccaucau      180

auguagcauu uacagauaca gaacgauuag uaggagaugc agcaaaauca caggcagcuc      240

uaaacccaca uaauacagua uuugaugcaa aaagacuaau agguagaaaa uuugcagaca      300

cuacaguaca aagcgauaug aaacauuggc cauuucaagu aguaucagaa gguggcaaac      360

caaaagucag aguauguuau agaggagaag auaaaacuuu uuaucccgaa gaaauaucau      420

caaugguauu aaguaaaaug aaagaaacag cagaagcaua ucuaggacaa ccaguaaaac      480

augcgguaau aacaguucca acauauuuuu caaacucaca aagacaagca acaaaagaug      540

ccggugcaau cgcaggacuu aaaguauuac caauaauuaa ugaagcaaca gcagcagcaa      600

uagcauaugg acuagauaga agaggagcug gaaaaagaaa uguauuaaua uucgauuuag      660

gagguggaac cuuugaugua ucaguauuaa gcauagaugc aggaguauuu gaagucaaag      720

caacagcagg agauacacau cuaggagggg aagauuucga uaauagauua guaaaucacu      780

uuauggaaga guuuagaaga aaacauggaa aagauuuaag cgguaauaaa agagcauuaa      840

gaagacuaag aacagcaugc gaaagagcaa aaagaacacc aucaagcagu acgcaagcaa      900

cauuagaaau agacucauua uucgaaggag uagacuuuua uaaaucaaua acaagagcga      960

gauucgaaga auuaugcuca gacuuauuca gaaguacacu agaaccagua gaaaaagcau     1020

uaagagaugc aaaacuugac aaagcacaaa uacaugauuu cguacuagga ggaggauuac     1080

acagucaucc acaaggagcu gaaguagcag caggacuauu acaacgacaa ggugcagaac     1140

aagaacauca accauaggga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  3666
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt12)

<400>  3666
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucaa       60

aagguccggc aguaggaauc gauuuaggaa caacauauag uugugucgga guauuucaac      120

auggaaaagu ugaaauaaua gcaaacgauc aaggcaauag aacuacacca ucuuacguug      180

cauuuacaga uacagaaaga uuaauagggg acgcagcuaa aaaccaagua gcaaugaacc      240

caacaaauac aguauuugac gcaaaacgac uaauaggaag aagauuugau gaugccguug      300

uacaaucuga caugaaacau uggcccuuua ugguaguaaa ugacgcagga agaccaaaag      360

uccaagucga auacaaagga gaaacaaaga gcuuuuaccc ugaagaaguu ucuagcaugg      420

uccuaacaaa aaugaaagaa auugcagaag cguaccuagg caaaaccgua acaaacgcag      480

ucgugacagu accagcauau uuuaacgauu cacaaagaca ggcaacaaaa gacgcaggaa      540

caauugcagg acucaacgua cuccgaauaa uaaaugaacc aacugcugca gcaaucgcau      600

auggguuaga caagaaagua ggagcagagc gcaauguacu aauauuugac cuaggaggag      660

guacguucga uguaagcaua uuaacaauag aagauggcau auuugaagua aaauccacag      720

caggagacac acacuuagga ggagaagauu uugacaauag aauggucaac cauuucauug      780

cagaguucaa aagaaaacac aagaaagaua uuucagaaaa uaaaagagca guaagaagau      840

uaagaacagc uugugaaaga gcuaaaagaa cuuuaucauc aucaacacaa gcuagcauag      900

aaauugacag uuuauaugaa ggaauagauu ucuauacauc caucacgcga gcaagguuug      960

aagaauuaaa ugcagacuua uuucgaggaa cacuugaccc uguugaaaaa gcccuacgag     1020

acgcuaaacu agacaaaagc caaauacaug acauaguucu aguaggagga agcacuagaa     1080

uacccaaaau acaaaagcua cugcaagacu ucuucaacgg aaaggaacuc aacaaaagca     1140

uuaaucccga ugaagcagua gcuuacggag cugcaguaca agcugcaaua uuaaguggag     1200

acaaaagcga aaacguacaa gaucuacuau uacuagaugu aacaccucua agccucggaa     1260

uagaaacggc aggaggagug augacaguac ucauaaaaag aaauacuaca auaccaacca     1320

aacaaacaca aacauuuaca acauacucag acaaucaacc aggaguauua auacaaguau     1380

acgaaggaga aagagccaug acaaaagaca auaaucuccu aggaaaauuc gaauuaacag     1440

gaauaccacc agcaccucgc ggaguaccac aaaucgaagu aaccuuugac auugaugcga     1500

acggcauauu aaauguuuca gccgucgaca agucuacagg aaaagagaac aagauaacaa     1560

uaacuaauga uaaagggcga uuaagcaaag aagauauaga acgaauggua caagaagcag     1620

aaaaauauaa agcagaagau gaaaaacaaa gagauaaagu aucuagcaaa aauagccuag     1680

aaaguuaugc auucaauaug aaagccacag uugaagacga aaaauuacaa ggcaaaauaa     1740

augacgaaga uaaacagaaa auauuagaca aauguaacga aauaauaaac uggcuggaua     1800

aaaaucaaac ggccgaaaaa gaagaauuug aacaucaaca aaaagaauua gaaaaaguau     1860

gcaauccgau aauaacaaaa uuauaccaau cagcuggggg uaugccaggg gguaugccag     1920

guggauuccc aggaggggga gcaccaccaa gcggaggagc aagcucagga ccaacaaucg     1980

aagaagucga cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  3667
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt12)

<400>  3667
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauau       60

ccgcaucaag agcagcagcg gcaagauuag uaggagcagc agcaaguaga ggaccaacag      120

cagcaagaca ccaagacagu uggaaugguu uaagccauga agcauuuaga cucgugagua      180

ggagagauua ugcaagugaa gccauaaaag gagcuguggu aggaauagau uuaggaacaa      240

cuaauucaug uguugcagua auggaaggaa aacaggcuaa aguacuagag aaugcggaag      300

gagcuagaac cacucccagu guaguagcau ucacagcuga uggagaaaga uugguaggga      360

ugccggcaaa aagacaagca guuacgaacc caaauaacac auuuuaugca acaaaacgac      420

uaauagggag gcgauacgau gacccggaag uucaaaaaga uauuaaaaac guuccuuuua      480

agauaguaag agccagcaau ggagaugccu ggguagaagc ccacggaaag uuauauucac      540

caagucaaau aggggcuuuu guacuaauga aaaugaaaga aacagccgaa aauuacuuag      600

gacauacugc uaaaaaugca guuauaacag uaccagcaua uuuuaaugau agccaaagac      660

aagcuacaaa agaugcaggu cagauaagug gucucaacgu ucugcgcgua auuaaugaac      720

caacagcugc ugcacuagca uacggguuag auaaaaguga agauaaaguc auagcgguau      780

augauuuagg aggaggcaca uuugauauau caauauuaga aauacaaaaa gggguauucg      840

aaguuaaaag caccaaugga gauacguuuc uuggagggga agauuuugac caagcguuau      900

uaagacauau agugaaagaa uuuaagagag agacaggagu agaucuaaca aaagacaaca      960

uggcauuaca aagaguuaga gaagcugcug agaaggcaaa augugaauua agcucaagug     1020

uacaaacaga uauaaauuua cccuauuuaa caauggauag caguggaccg aaacaucuaa     1080

auaugaaauu gaccagagcu caauuugaag gaauagugac agauuuaaua aggagaacaa     1140

uagcaccaug ccagaaagca augcaagaug cagaggugag uaaaagcgau aucggagaag     1200

ugauauuggu aggaggaaug acaagaaugc caaaaguaca acaaacagua caagacuuau     1260

uuggcagagc accaagcaaa gcuguuaacc cagaugaagc aguggcuauu ggagcagcua     1320

uacaaggagg aguguuagca ggagauguaa cagauguauu auuacuagau guaacaccau     1380

uaucauuggg uauagaaaca cuaggagggg uauuuacaaa gcuaauaaau agaaauacaa     1440

caauaccaac aaagaagucu caaguauucu caacugcagc agaugggcaa acacaaguag     1500

aaauaaaagu augucaagga gaaagagaaa uggcaggcga caauaaacua cuuggacaau     1560

uuacacuaau aggcauaccg cccgccccca ggggaguucc acaaauagaa guaaccuucg     1620

auauagaugc caacggaaua guacacguaa gcgcaaagga caaagggaca gggagagaac     1680

aacaaauagu aauacaaucc agcggagguu uaucaaaaga cgacauagaa aacaugguua     1740

aaaaugcaga gaaguaugca gaagaagaua gaagaaagaa agaaagagua gaagcaguaa     1800

auauggcaga ggguauuaua caugauacgg aaacaaaaau ggaagaauuu aaagaucaau     1860

uaccugcaga cgaaugcaau aaacuaaaag aagaaauaag caaaaugaga gaauuacuag     1920

caagaaaaga uucggaaacu ggagaaaaua uaagacaagc agcuaguagc cugcagcaag     1980

ccagcuuaaa acuauucgag auggcauaua agaaaauggc aagcgaaaga gaaggcagug     2040

ggagcucagg aacaggugaa caaaaagaag accaaaaaga agaaaaacaa uaaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  3668
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt12)

<400>  3668
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcug       60

auaaagaagc uggagguucu gauggaccac gagaaacagc uccaacuucu gcuuacucaa      120

guccagcaag gucuuuagga gacacgggaa uuaccccguu aagucccagu cauauaguca      180

acgauacuga uucuaacgug uccgaacaac aaagcuuucu uguaguagua gcaguugacu      240

ucggaacuac uucaucagga uaugcguauu cauuuacaaa agaaccagaa uguauccacg      300

ugaugagacg augggaagga ggagaucccg gaguaagcaa ucaaaaaaca ccgacaacaa      360

uacucuuaac accagaacga aaauuccauu cauuuggcua cgcagcuaga gauuucuauc      420

augaucuaga uccaaaugaa gcaaaacaau gguuauaucu ugaaaaauuu aaaaugaaac      480

uacauacaac aggugaccuc acaauggaua cugaucuaac agcagcaaau gggaagaaag      540

uuaaagcacu agaaauauuu gcauacgccc uucaauacuu uaaagaacaa gcacuuaaag      600

aacuaucaga ucaagcagga ucugaauuug aaaauagcga uguuagaugg guaauaacag      660

uuccagcaau auggaaacaa ccagcaaaac aauuuaugcg ccaagcugca uaccaagcag      720

gacucgccuc uccagagaau ucagaacaau uaauaauugc auuagaaccu gaagcagcca      780

guauauauug cagaaaacua agauuacauc aaaugauuga auuaaguagu aaagcagcag      840

uaaacgguua uagugguuca gauacaguag gagcuggcuu uacucaagca aaagaacaua      900

uaagaagaaa uagacaauca aggacauuuu uaguagaaaa uguaauuggu gaaauauggu      960

ccgaauuaga agaaggagac aaauauguag ucguagacuc ugguggcgga acuguagacc     1020

uaacaguaca ucaaauaaga cuuccagaag gacaucuaaa agaauuauau aaagcaacgg     1080

gaggccccua uggaucauua gguguagauu augaauucga aaaauuauua uauaaaauau     1140

uuggcgaaga uuuuauagaa caauucaaaa uaaaaagacc ugcggcuugg guagacuuaa     1200

ugauagcuuu ugaaucaaga aaaagagcug ccgccccaga cagaacaaau ccauuaaaua     1260

uaacauuacc auuuucauuu auugauuauu auaaaaaauu uagaggacac ucuguagaac     1320

augcacuuag aaaaagcaac guagauuuug uaaaauggag uucucaagga auguuaagaa     1380

ugucaccaga cgcaaugaac gccuuguuca aaccaacgau ugauaguaua auagaacacu     1440

uacgcgacuu auuucaaaaa ccagaaguau caacagucaa auuucuauuu uuagucggag     1500

gauuugcaga agcaccacuu cuacaacaag caguacaagc agcauuugga gaucaaugca     1560

gaaucauaau accucaagac guaggccuca cgauucuaaa aggcgcagug cuauucgguc     1620

uagauccagc aguuauaaaa guucggcgau cacccuuaac auauggaguu ggaguauuaa     1680

aucgauacgu agaaggaaaa cauccaccag aaaaauuauu aguaaaagac gguacgagau     1740

gguguaccga uguauucgau aaauuuauau cagcagacca aucaguagcu cucggcgaac     1800

ucguuaaaag auccuauaca ccagcaaaac caucucaauu aguuauagua auuaauauau     1860

auucaagcga gcacgauaac guuucauuua uaacagaucc agguguaaaa aagugcggua     1920

cauuaagacu cgacuuaacc ggaacaagug gaacagcagu uccagcacgc agagaaauac     1980

aaacauuaau gcaauuuggu gauacugaaa uaaaagcaac agccauagac auagccacau     2040

caaaaucagu uaaaguugga auagacuuuc uaaauuacug aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  3669
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt12)

<400>  3669
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguuag       60

caguaccaga aaugggauua cagggacuau auauuggauc uucuccagaa agaucaccag      120

uaccaucacc acccggguca ccaagaaccc aagaaagcug uggaauagcu ccacuaacac      180

caucacaauc cccuaaacca gaaguaaggg caccccaaca agccaguuuc aguguuguag      240

uagcaauaga uuuuggaacu acaucaucag guuacgcauu uuccuuugca ucagauccug      300

aagcaauuca uaugaugaga aaaugggaag gaggagaccc uggcguagca caucagaaaa      360

cuccuacaug uuuacuuuug acaccagaag gagcauuuca uucauuugga uauacagcac      420

gagauuauua ucacgacuua gauccagaag aagcuagaga uuggcucuac uuugaaaaau      480

uuaaaaugaa aauacauagu gcaacagauc uaacauuaaa aacccaauua gaagcuguua      540

augguaaaac uaugccagcg cuagaaguau uugcgcacgc auuaagauuu uuccgagaac      600

augcauuaca agaacuuaga gaacaaucac cuucacuacc ugaaaaagau acaguuagau      660

ggguauugac uguaccggca auauggaaac aaccagcgaa acaauuuaug agagaagcug      720

cauauuuagc uggguuagua ucacgagaaa augcagagca acucuuaauu gcgcuugagc      780

cagaagcagc aucugucuac ugcagaaaau uaagacuaca ucaacuacua gauuuaagug      840

gcagagcacc cggaggugga agacuaggug agcgaagaag cauagauuca aguuuccgac      900

aagcaagaga gcaacuaaga cgaucaagac acucaagaac auuucuagua gaaagcggug      960

uaggagaauu augggcagaa augcaagcag gagaucgaua uguaguugcc gauugcgggg     1020

guggcacagu agauuuaaca guccaucaac uagaacaacc acacggaacu cuaaaagaac     1080

uauauaaagc aucaggaggu ccauacggcg caguaggagu ggacuuagcg uucgaacaac     1140

uacuaugcag aauauuugga gaagauuuua uagcgacauu uaaaagacaa agaccugcgg     1200

ccuggguaga ucuaacaaua gcauucgaag caagaaaacg gacggccggg ccgcauagag     1260

caggagcucu aaauauaagc cuaccauuuu cauuuauaga cuuuuauaga aaacagagag     1320

gacauaacgu ugaaacugca cugagacgau ccucaguaaa uuucguaaaa uggucuucac     1380

aaggaauguu gcgaaugagc ugcgaagcaa ugaaugaacu auuucaacca acuguaagug     1440

gcauuauuca acauauagaa gcacuauuag caagaccuga aguccaagga guuaaacugc     1500

uauuccuggu agguggauuu gcagaaucgg caguauuaca gcaugcagua caagcagcuu     1560

uaggugcaag aggauuacga guaguaguac cacaugaugu aggacuaaca auuuuaaaag     1620

gagcuguacu auucggccaa gcuccaggag uuguaagagu uagaagaagu ccauuaaccu     1680

acgggguagg gguacuuaau agauucguac cuggacgaca uccaccagaa aaauuauuag     1740

uaagggaugg aagacgcugg uguacagaug uguucgaaag auucguagcu gcugaacaga     1800

gcguugcucu aggggaagaa guacgaagau cauacugucc agcuagacca ggccaaaggc     1860

gaguauuaau aaauuuauau uguugugcag cagaagaugc aagauucauc acugauccag     1920

gaguuagaaa augcggagca cucucucuag aguuagaacc ugcggacugu ggacaagaca     1980

ccgcaggagc cccaccagga aggagagaaa uacgagcagc aaugcaauuu ggugauacag     2040

aaauuaaagu cacugcagua gauguaucga caaauagauc aguaagagcu ucgauugauu     2100

uccuuucgaa uuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  3670
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt12)

<400>  3670
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcuc       60

gagaaaugac aauuuuagga ucagcgguau ugacacuuuu auuagcagga uaccuagccc      120

aacaauaccu accacuaccu acaccaaaag ugauaggaau agaccuugga acaacauacu      180

guucaguagg aguauucuuu ccaggaacag guaaaguaaa aguaauacca gaugaaaacg      240

gacacauaag uauacccuca augguaaguu uuaccgauaa cgauguauac guaggauacg      300

aaucaguuga auuagcagac ucaaauccac aaaacacaau auaugacgca aaaagauuua      360

ucggaaaaau cuucacagca gaggaauuag aagcagaaau aggaagauau cccuucaaag      420

uauuaaauaa aaacggaaug guagaauucu cugucacauc aaacgaaaca auaacaguaa      480

gcccagaaua cguaggcagu cgauuacuac uaaaacucaa agaaauggca gaagcguacu      540

uaggaaugcc aguagcaaau gccguaauau cagucccagc agaauucgau cuaaaacaac      600

gaaacagcac cauagaagca gccaaucuag caggauuaaa aauacuaaga guaauaaacg      660

aaccaaccgc agcagccaug gcauauggac uacacaaagc agauguauuu cacguauuag      720

uaauugaucu aggaggcgga accuuagacg uaucauuauu aaauaaacaa ggaggaaugu      780

ucuuaacuag agccauguca ggaaauaaca aacuaggagg acaagauuuu aaccaacgac      840

ucuuacaaua cuuauacaaa caaauauauc aaacauaugg auuuguuccu agcagaaaag      900

aagaaauaca uagacuaaga caagccguag aaaugguuaa auuaaaucuu acacuccacc      960

aaagugcaca acuaagcgug uuacuaacag uagaagaaca agacagaaaa gaaccacacu     1020

cuucagacac agaauuacca aaggauaaau uaucaucagc agaugaccac cgaguaaauu     1080

caggauucgg aagaggacua ucagauaaaa aaucaggaga aucacaaguu cuauucgaaa     1140

cagaaauauc aagaaaacua uuugacacau uaaacgaaga uuuauuccaa aaaauacuag     1200

uaccaauaca acaaguacuu aaagaaggac aucuugaaaa aacggaaaua gacgaaguag     1260

uacucguagg agguucaaca agaauaccaa gaauaagaca aguaauucaa gaauuuuuug     1320

gaaaagaccc aaauacaucc guagauccag aucuagccgu aguaaccggc guagcuauac     1380

aagcaggaau agauggugga ucauggccau uacaaguauc agcacucgaa aucccaaaca     1440

agcacuuaca aaaaacaaau uucaacuaag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3671
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt12)

<400>  3671
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

caaucggagu ucaucuagga uguacaagcg caugcguagc aguauacaaa gacggucgag      120

cagguguugu cgcaaacgau gcaggagaua gaguaacacc agcuguagua gcauauagug      180

aaaacgaaga aauaguagga uuagcagcaa aacaaagcag gauucgaaau auaucaaaua      240

caguaaugaa aguaaaacaa auauuaggcc gaagcagcuc cgacccucaa gcacaaaaau      300

auauagcaga aaguaaaugu uuaguaauag aaaaaaaugg aaaacuaaga uacgaaauug      360

auacgggaga agaaacaaaa uucguaaauc cggaagaugu agcaaggcua auauuuagca      420

aaaugaaaga aacagcucau aguguauuag gaagcgacgc aaacgacgua guuauaacag      480

ucccuuucga uuuuggagaa aaacaaaaaa augcucuugg agaagccgca agagcagccg      540

gcuuuaaugu acuaagacua auacaugaac caucagcagc ucuauuagca uauggaaucg      600

gacaagauuc accaacaggu aaaaguaaca uacuaguauu uaaauuagga ggaacaucau      660

uaucacuauc cguaauggaa guaaauucag gaaucuauag aguauuaagu acaaacacag      720

acgacaacau uggaggagca cacuuuacag aaacuuuagc acaauaucuu gcauccgaau      780

uucaaagaag uuuuaaacau gacguaagag guaacgcaag agcgaugaug aaacugacaa      840

auucagcaga aguagcaaaa cauagucuau caacauuagg auccgcaaac ugcuuucuag      900

auaguuuaua ugaaggacaa gacuuugacu gcaauguauc aagagcacgu uucgaacucu      960

uauguucacc guuauuuaau aaaugcauag aagcaauaag aggacuauua gaucaaaaug     1020

gauuuacagc ugaugauaua aauaaaguug uguuaugugg aggaucauca agaauaccaa     1080

aauuacaaca auuaauaaaa gauuuauuuc ccgcaguaga auuauuaaau ucaauaccac     1140

cagacgaagu aauuccaaua ggcgcagcca ucgaagcagg cauacuaaua ggaaaagaaa     1200

accuauuagu agaagacuca uuaaugauag aauguucagc aagagauaua uuaguaaaag     1260

gaguagauga aaguggugcg ucaagguuua caguauuauu uccaagcgga acaccacuac     1320

cugcaagaag acaacauacg cuacaagcac cagguaguau aaguucagua ugucuagaac     1380

uauaugaauc cgacggaaaa aacagcgcaa aagaagaaac aaaauuugca caaguuguuu     1440

uacaagauuu agauaaaaaa gaaaacggcu uaagagacau uuuagcagua uuaacaauga     1500

aacgcgaugg aucacuacau guaacaugua cagaccaaga aacaggaaaa ugcgaagcaa     1560

uaaguauaga aauagcuuca uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  3672
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt12)

<400>  3672
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucag       60

uaguaggacu ugauguagga ucacaaucau guuacauagc aguagcuaga gccgguggga      120

uagaaacaau agcaaacgaa uuuagugaua gaugcacacc aagugucaua ucauuuggua      180

gcaaaaacag aacaauagga guagcagcga aaaaccaaca aauaacccac gcaaacaaca      240

caguaucaaa cuucaaaaga uuccacggca gagcauuuaa cgaccccuuc auacaaaaag      300

aaaaggaaaa cuugaguuau gacuuaguac cacucaaaaa uggaggaguu ggaauaaaag      360

uaauguacau gggggaagaa cacuuauuua gcguagaaca aauuacugca augcuauuaa      420

caaaacuuaa agaaacagca gaaaacucau uaaagaaacc aguaacagau uguguaaucu      480

ccguaccauc uuucuuuaca gaugcagaaa gacgauccgu cuuagacgca gcacaaauag      540

uuggccuaaa uuguuuaagg uugaugaacg acaugacugc cguagcccua aauuauggua      600

uuuacaaaca agacuuacca agccucgaug agaaaccccg gauaguagua uuuguagaca      660

ugggacacag cgcauuucaa gugagugccu gugccuuuaa caaaggaaaa cucaaaguuc      720

ucgguaccgc cuuugauccg uuuuuaggag gcaaaaauuu cgacgaaaaa uuagucgaac      780

auuuuugcgc agaauuuaaa acaaaauaua aauuagacgc gaaaagcaaa auaagagcgc      840

uacugagauu auaccaagaa ugugaaaaac uaaagaaacu aaugaguuca aauaguacag      900

accuaccacu aaauauagag uguuucauga acgacaaaga cguaagcgga aaaaugaaua      960

gaucacaguu cgaagaacuu ugugcagaac uauuacagaa aauagaaguu cccuuauauu     1020

cauuauuaga acaaacacac uuaaaaguag aggaugucuc agcuguagaa aucgucggag     1080

gagccacccg uauuccagcg gucaaagaaa gaauagcaaa auucuuuggc aaagacauaa     1140

guacaacccu aaacgccgau gaagcagucg caagaggaug ugcacuccaa ugugcaaucc     1200

uuaguccagc cuuuaaagua agagaguuuu ccguaacuga cgcaguacca uuuccuauuu     1260

cucuaauuug gaaucaugau ucagaagaua cagaaggagu acaugaagua uuuucaagaa     1320

accaugcagc accguucagu aaaguauuga cauuuuugcg aagaggccca uucgaacuag     1380

aagcauuuua cucagaucca caagggguac cauaccccga agcaaaaauc ggaagauuug     1440

uuguacaaaa cgucucagca caaaaagaug gagagaaaag cagaguaaaa guaaaaguac     1500

gaguaaacac ucauggaaua uucacaauau cuaccgcaag caugguagaa aaagucccaa     1560

cagaagaaaa cgaaauguca agcgaagccg auauggaaug cuugaaucaa cgaccgcccg     1620

aaaacccaga uacugacaaa aacguacaac aagauaauuc agaagcugga acucaaccac     1680

agguacaaac cgaugcacaa caaaccucac aaagcccacc aagucccgaa cuuacguccg     1740

aagaaaacaa aauaccagac gcagauaaag caaacgagaa gaaagucgac caaccaccag     1800

aagcaaagaa accgaaaaua aaaguaguga auguagaauu accaauagaa gccaaccuag     1860

uguggcaacu aggaaaagac cuccuaaaca uguacauuga aacagaagga aaaaugauaa     1920

ugcaagauaa auuggagaaa gaaagaaacg acgccaaaaa ugcaguagaa gaauacgucu     1980

acgaguucag agauaaacua ugugguccau augaaaaauu cauaugugaa caagaucacc     2040

aaaauuuccu uagauuacuu acagaaacug aagauugguu auaugaagaa ggcgaagauc     2100

aagcaaaaca agccuacguc gacaaauuag aagaauuaau gaaaauagga acaccaguga     2160

aaguaagauu ccaagaagca gaagaaagac caaaaauguu ugaagaauua ggucagcgcu     2220

uacaacauua cgccaaaauu gcagcagauu uuagaaauaa agaugaaaaa uauaaccaua     2280

uugacgaauc agagaugaag aaaguagaaa aaucagucaa ugaaguaaug gaauggauga     2340

auaauguaau gaacgcucaa gcaaagaaau cauuagacca agacccagua gugagagccc     2400

aagaaauaaa aacaaaaaua aaagaauuaa auaauacaug ugaaccuguu guuacacaac     2460

caaaaccaaa aauagaaagu ccaaaacuag aacgaacgcc aaacggacca aauauagaca     2520

agaaagaaga agaucuagaa gacaaaaaua acuucggugc agaaccucca caucaaaacg     2580

gagaauguua cccaaacgag aaaaacagug uaaacaugga cuuagacuaa ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  3673
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt12)

<400>  3673
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

auaaaguaag gcgccaacgu ccaagaagaa gaguauguug ggcacuuguu gcaguucuac      120

uugcagacuu auuagcacua agugauacac uugcagugau gaguguagau cuuggauccg      180

aaagcaugaa aguagcaauc guaaaacccg gaguaccaau ggaaauugua cucaacaaag      240

aaagucgaag aaaaacacca guaaucguaa cucuaaaaga aaaugaaaga uuuuucgggg      300

auucugcagc aucuauggca auuaaaaacc caaaagcuac auuacguuac uuccaacauu      360

uacuugguaa gcaagcagau aacccucacg uugcucuaua ucaggcucgu uucccagaac      420

augaacucac auucgaccca caacgacaga caguacacuu ucaaauauca agccaauuac      480

aauucucacc agaagaagua cuagguaugg uacuaaacua uucgcgaagu uuagcagaag      540

acuucgcuga acaaccaaua aaagaugccg uaauaacagu cccagucuuc uuuaaccaag      600

cagaaaggag agccguucua caagcggcua gaauggcagg auuaaaagua uugcaacuaa      660

uaaaugacaa uacugcgacc gcccuaaguu acggcguuuu ucgaagaaaa gauauaaaua      720

caacagccca aaacauaaug uucuacgaca ugggaagugg aucaacagua ugcacuauag      780

uuacauacca aaugguaaaa acgaaggaag caggaaugca accacagcua caaauaagag      840

gaguaggauu ugaucguaca cuaggaggau uagaaaugga acuaagacuu agagaacgcu      900

uagcaggauu guucaaugaa caaagaaagg gccaacgcgc caaggaugug agagagaauc      960

caagagcaau ggcaaaauua cucagagagg ccaaccgguu aaaaacagug uuaucagcaa     1020

acgcagauca uauggcucag auagaaggac ugauggauga cguugauuuc aaagcaaaag     1080

ucacacgagu ugaauuugaa gaguuaugug cagauuuauu cgaaagaguu ccuggaccug     1140

uucaacaagc gcuacaaagu gcagaaauga guuuagauga gauugaacaa gugauucuag     1200

uuggcggagc aacucgaguu ccaagagucc aagaaguacu guuaaaagcc guaggcaaag     1260

aagaauuagg uaaaaauaua aaugccgaug aagcagccgc aaugggagcc guuuaucaag     1320

cugcugccuu aucgaaagca uuuaaaguaa aaccauuugu uguaagggac gccgugguau     1380

acccaauauu agucgaguuu acacgagaag ucgaagaaga acccggaaua cauucauuaa     1440

aacauaacaa acgaguucua uuuucaagaa uggggccgua uccacaaaga aaaguaauaa     1500

ccuuuaauag auacucccac gauuuuaauu uccacauuaa uuauggagau cuaggauuuu     1560

uagguccgga agaucuucgu guauuugggu cacaaaauuu gacaacaguc aaacuaaaag     1620

gagucggaga cucauuuaag aaauauccag auuaugaauc aaaaggaauu aaagcucauu     1680

ucaauuugga ugaaagugga guacucaguc uagauagggu agaaagcgua uuugaaacau     1740

uagucgaaga cucagcagaa gaagaaagca cucugacuaa acuaggaaau acaauaucau     1800

cacuauucgg aggugggacg accccagaug caaaagaaaa uggaacagau acuguacagg     1860

aagaagaaga aucaccagca gaaggaagca aggaugaacc aggugagcaa guagaacuaa     1920

aagaagaagc agaagcacca guagaagacg gaagucaacc accuccacca gaaccuaaag     1980

gagacgcgac cccagaagga gaaaaagcua cagaaaagga aaauggagau aaaucagaag     2040

cucaaaaacc gucagaaaaa gcugaagcag gaccagaagg cguugcccca gcaccggagg     2100

gagaaaagaa acaaaaacca gcaagaaaaa gaagaauggu ggaagaaauc gguguagagc     2160

uaguaguauu agacuuaccu gacuuaccag aagauaaauu ggcucaaucc guucaaaaac     2220

uucaagaucu aacacuuaga gacuuagaaa aacaagaacg agaaaaagca gcaaacucac     2280

uagaagcauu uauauucgaa acacaggaua aacuauacca accagaauac caagagguuu     2340

caacugagga acaaagggaa gagaucucag gaaaacucag ugcagccagu acaugguugg     2400

aagacgaagg aguaggcgca acaacgguca uguuaaaaga aaaacuagcg gaacuuagaa     2460

aauuaugcca aggauuauuu uucagaguug aagaaagaaa gaaauggcca gaaagauuau     2520

ccgcuuugga uaauuuauua aaucauucau caauguuucu aaaaggcgca agauuaauac     2580

cugaaaugga ucaaauauuc acagaaguag aaaugacuac auuagaaaaa guaauaaaug     2640

aaacuugggc uuggaaaaau gcuacacuag cagaacaagc aaaauuacca gcuaccgaaa     2700

aaccaguacu acuaucaaaa gacauagagg caaaaaugau ggcccuagac agagaaguuc     2760

aauaucuacu aaauaaagca aaauuuacua aaccuagacc aagaccuaaa gauaaaaaug     2820

guacacgagc ugagccucca cucaaugcgu ccgcauccga ucaaggagaa aaaguuauac     2880

ccccugccgg acaaacagaa gacgcagagc caaucucaga accagaaaaa guggaaacag     2940

gaagugaacc uggagacaca gaaccacuag aacucggagg uccgggggca gaaccagaac     3000

aaaaagaaca gaguacagga caaaaacgac cgcuaaagaa ugaugaguua uaaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3674
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt12)

<400>  3674
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

aggaaaccca aacucaagau caaccaaugg aagaagaaga aguagaaaca uuugcuuucc      120

aagccgaaau agcacaacug augucacuaa uaauaaauac auuuuauuca aacaaggaaa      180

uuuucuugag agaacucaua aguaacucaa gcgacgcacu cgacaaaaua agauacgaaa      240

gccuaacaga cccgucuaaa cuggacucag gaaaagagcu acauauaaac cuaauaccua      300

acaaacaaga uagaacacua accauaguag auacaggaau agguaugaca aaagcagauu      360

uaauaaacaa ccuaggcaca auagccaagu ccggaaccaa agcguucaug gaagcgcucc      420

aagccggcgc agauaucagc augauaggac aauucggggu aggauucuac ucagcauauc      480

uaguagcaga aaaaguaacg guuaucacca aacauaauga cgacgaacag uacgcauggg      540

aaaguucggc aggcggcuca uucacaguca gaaccgacac cggggaacca augggaagag      600

guacaaaggu aauacuacac cuuaaagaag accaaacaga auaccuagaa gaaaggagaa      660

uaaaagaaau aguaaaaaaa cacucacaau ucauuggaua cccaauaaca uuauuuguag      720

aaaaagaaag agacaaagaa guaagcgacg augaagcaga agaaaaagaa gauaaagaag      780

aagagaaaga aaaagaagag aaagaaagug aagacaaacc agaaauagaa gacguuggcu      840

cggaugaaga agaagaaaaa aaagacggag auaaaaaaaa aaaaaaaaaa auaaaagaaa      900

aguacauaga ucaagaagaa cucaauaaaa caaagccaau auggacacga aauccagaug      960

acauaacuaa cgaagaauac ggcgaauuuu auaaaaguuu aacaaacgac ugggaagacc     1020

aucucgcagu aaaacauuuu ucaguagaag gacaacuaga auucagagca cuauuauucg     1080

uccccagaag agcaccauuu gauuuauuug aaaauagaaa aaaaaaaaac aacauuaaac     1140

uauauguaag aagaguuuuc auaauggaca auugugaaga auuaauacca gaauaucuaa     1200

acuuuauaag aggggugguu gacagcgaag auuuaccgcu uaacauaagc cgagaaaugu     1260

ugcaacagag uaaaauacua aaaguaauaa gaaaaaaucu aguaaaaaaa uguuuagaau     1320

uauuuacgga auuagcagag gacaaagaaa acuacaagaa auuuuacgaa caauucagua     1380

aaaacauaaa auuaggcaua cacgaagaca gucaaaauag aaagaaacua ucagaacuac     1440

uaagauauua cacaagugca aguggagaug aaaugguaag cuuaaaagac uacuguacaa     1500

gaaugaagga aaaccaaaaa cauauauauu auauaacagg agaaacaaaa gaucaaguag     1560

caaacagugc cuucguagaa agacuaagaa aacaugggcu agaaguaaua uacaugauag     1620

aaccuauaga ugaauauugc guacaacaac uaaaagaauu ugaaggaaaa acccuaguau     1680

cgguaacaaa ggaaggauua gaauuacccg aagaugaaga agaaaaaaag aaacaagaag     1740

aaaaaaaaac aaaauucgaa aaccuaugca aaauaaugaa agauauacua gaaaaaaaag     1800

uugaaaaagu ugugguaucu aacagauuag uaacuucacc augcugcauc guaacuagua     1860

cguauggcug gacagcaaac auggaaagaa uaaugaaagc acaggcuuug agagauaaca     1920

guaccauggg auauauggca gcaaaaaaac aucuagaaau uaauccagac cacaguauaa     1980

uagaaacguu aagacagaaa gcagaagcgg acaagaacga caaaucagua aaagaccucg     2040

uuauacuacu cuaugaaaca gcacuacuaa gcaguggauu uucauuagaa gauccacaga     2100

cacacgcaaa caggauuuau agaaugauua aacuuggacu cggaauagac gaagaugacc     2160

caacagcaga ugacacaagu gcagcaguga ccgaagaaau gccaccguua gaaggggaug     2220

acgacacuag uagaauggaa gaaguagauu aaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  3675
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt12)

<400>  3675
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcucaaaacu agacucagga aaaggacuac acauaaaccu aguaccaaac aaacaaaacc      120

aaacacuaac aauaguagac acaagaauag gaaugacaaa aacagaccua auaaacaacc      180

uaggaacagu aacaaaaagc ggaacaaaag cauuuaugga agcacuacaa gcagacgcag      240

acauaagcau gauaggacac uucggaguag gauucuacuc agcauaccua guagcaaaaa      300

aaguaacagu aauaucaaaa cacaacaacg acgaacaaua cacaugggaa ucaagcgcag      360

gaggaagcuu cacaguaaga acagacgaau aaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  3676
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt12)

<400>  3676
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

aagaaguaca ccauggagaa gaagagguag aaacauucgc auuucaagca gagauugcac      120

aacuaaugag uuugauaaua aauacauuuu auagcaacaa agaaauauuu uuaagagaac      180

uaauuucuaa cgcaagcgac gcauuagaca aaauacgaua ugagagucua acugauccaa      240

guaaacuaga uaguggaaag gaacuuaaaa uagacauaau accgaaucca caagaacgaa      300

cauugacacu aguggacaca ggcauaggaa ugacaaaggc cgaucuaaua aauaaucuug      360

gcacaauagc aaaaaguggg acuaaagcgu uuauggaggc acuacaagcg ggagcagaua      420

uaaguaugau aggacaauuu ggaguuggau uuuauucagc auacuuagug gcagaaaaag      480

uugucguaau aacaaaacau aacgaugacg aacaauacgc cugggaauca agcgcaggag      540

gaaguuuuac aguaagagca gaccacggug aaccaaucgg aaggggaaca aaaguaauac      600

uacacuuaaa agaagaucaa acagaguauu uggaagaacg aaggguaaaa gaaguaguaa      660

aaaaacacuc acaauuuaua ggauauccga uaacauugua ccuagaaaag gaaagggaaa      720

aagaaauaag cgaugacgaa gcagaagaag aaaaagggga aaaggaagaa gaagauaaag      780

acgaugaaga aaaaccaaaa auagaggacg uaggaaguga ugaagaagau gacucaggaa      840

aagauaaaaa aaaaaaaacu aaaaaaauca aagaaaaaua cauagaucaa gaagaauuaa      900

auaaaacaaa gccaauaugg accagaaacc cagacgacau aacacaagaa gaauauggcg      960

aauucuauaa aagucuaaca aaugacuggg aagaccaccu agcaguaaaa cacuucagcg     1020

ucgaagguca auuagaauuc agagcucuac uauuuauacc aagaagagca ccauucgauc     1080

uauucgaaaa caaaaaaaaa aaaaauaaua uaaaacucua cguccgcaga gucuuuauaa     1140

uggacucgug cgacgaacua aucccagaau auuuaaacuu uaucagaggg guaguagacu     1200

cagaggaccu cccacuaaac auaagcaggg aaaugcuuca acaaagcaaa auccuaaagg     1260

uaaucagaaa aaauaucguc aaaaaaugcc ucgaacuauu uucagaauua gccgaagaua     1320

aagaaaacua caaaaaauuu uacgaagcau ucagcaaaaa uuuaaaacua ggcauacacg     1380

aagacuccac aaacagaaga agauuaagcg aauuacuaag auaucacaca ucacagucgg     1440

gagaugaaau gacaucuuua ucagaguacg uaagccgaau gaaagaaaca caaaaaagua     1500

uauacuauau cacuggagaa aguaaagaac aaguagcgaa cucagcauuu guagaacgug     1560

uaagaaaacg aggauuugaa guaguauaca ugacagaacc aauugacgaa uacugugucc     1620

aacaauuaaa agaauucgau gguaaaaguu uaguuucagu aacaaaagaa ggauuagaau     1680

uaccugaaga cgaagaagaa aagaaaaaaa uggaagaaag caaagcaaaa uuugaaaauc     1740

uaugcaaacu caugaaagaa auauuagaca aaaaagugga aaaagucacg auuuccaaca     1800

gacucguaag cucacccugu ugcauaguaa caucuacaua ugguuggacu gcaaacaugg     1860

aaagaauaau gaaagcacaa gcuuugagag acaauucaac aaugggauau augauggcaa     1920

agaaacauuu agaaauaaac ccagaccauc caaucguaga aacacugaga caaaaggcag     1980

aagcagacaa aaaugauaag gccgugaaag aucuuguggu acuucuauuc gaaacagccc     2040

uacugaguag uggauucagu uuagaagacc cacaaacaca cuccaauaga aucuaucgaa     2100

ugaucaaacu aggauuagga auagacgagg augaaguagc ugcagaagaa ccaaaugcag     2160

caguaccaga ugaaauacca ccgcuagaag gagaugaaga ugcgagccgc auggaagaag     2220

uagacuaggg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  3677
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt12)

<400>  3677
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagag       60

cacugugggu auuaggauua ugcugcguau uacuaacguu uggaucagug agagcagaug      120

augaagucga uguugaugga acaguagagg aagaccucgg uaaaaguaga gaaggcucaa      180

gaacugacga cgaaguuguu caaagagaag aagaagcgau acaauuagau ggauuaaaug      240

caucacaaau aagagaacuu cgugaaaaau cagaaaaauu ugcguuucaa gcagaaguaa      300

acagaaugau gaaacuaaua auaaauucau uauacaaaaa uaaagaaaua uuuuuaagag      360

aacuuauuuc aaacgcaagc gaugcauugg auaaaauaag auugauaagu cuaacagaug      420

aaaacgccuu aucaggaaau gaagaauuaa caguaaaaau aaaaugcgau aaagagaaaa      480

auuuacuaca uguaacugac acgggaguag gaaugacaag agaagaauua gucaaaaauu      540

ugggaacaau agccaaauca ggaaccucag aauuucuaaa caaaaugacu gaagcacaag      600

aagacgggca aucaacaagu gaauuaauag gacaauuugg gguaggauuc uacagugcgu      660

uuuuaguagc ggacaaggua auaguaacca guaaacauaa uaacgacaca caacauauau      720

gggagucaga caguaacgag uucaguguaa ucgcagaccc gagagguaac acauugggac      780

gaggaacaac uauaacguua guacucaaag aagaggcuuc agauuaccua gaacuggaua      840

caauaaagaa ucucgugaag aaauauuccc aauucaucaa cuucccaaua uacguaugga      900

guucaaaaac agaaacagug gaggaaccaa uggaagaaga agaagcagcu aaagaagaga      960

aagaagaauc agaugaugaa gcugcagucg aagaagaaga agaagaaaag aaaccgaaaa     1020

cuaagaaagu agagaaaaca guuugggauu gggaacuaau gaacgacaua aaaccaauuu     1080

ggcaacgacc gucaaaagaa guggaagagg augaauauaa agcauuuuac aaaucauucu     1140

cuaaagaauc agaugaucca auggcauaua uacauuuuac agcagaaggg gaaguaacau     1200

uuaagucaau ccuauuugua ccaaccucag caccgagggg auuauucgac gaauauggaa     1260

gcaagaaauc ggauuauaua aaacuauaug uaagaagggu auuuauaacc gaugauuucc     1320

acgauaugau gcccaaauau cuaaauuuug uaaaaggagu aguagacagc gacgaucuac     1380

cauuaaaugu aucucgagaa acacuccaac agcauaaacu ccuaaaaguu auaaggaaga     1440

aauuagucag gaaaacacuc gauaugauaa agaaaauagc agaugauaaa uauaacgaca     1500

cauuuuggaa agaauuuggu acaaauauua aauuaggagu aaucgaagau cacaguaaca     1560

gaacgagauu agcaaaacua uugagauuuc aaaguucaca ccacccaaca gauauaacua     1620

gcuuagacca auauguggaa aggaugaaag aaaaacaaga uaaaauuuau uuuauggcag     1680

ggaguaguag gaaagaagcu gaaaguagcc ccuucgugga aagauuauua aagaaaggau     1740

augaaguaau auaucuaaca gaaccaguag acgaauauug uauacaagca cuaccagagu     1800

ucgacggaaa aagauuucaa aauguagcca aagaaggagu aaaauuugac gagucagaga     1860

aaacaaaaga aagcagagaa gcaguagaaa aagaauuuga accucuacuu aacuggauga     1920

aagauaaggc uuuaaaagau aaaauagaaa aagcaguagu aagccaaaga cuuacagaau     1980

caccaugugc auugguagca agucaauaug gauggagugg aaacauggaa aggauaauga     2040

aagcacaagc guaccaaaca ggaaaagaua uaucaacgaa uuacuaugcc agccagaaaa     2100

agacauucga aauaaaucca agacacccau uaauaagaga cauguuaaga agaauuaaag     2160

aagaugaaga ugauaaaacu guauuagacc uugcaguagu uuuguucgaa acggcaacau     2220

uacgaagugg cuaucugcua ccggauacaa aagcauaugg agacagaaua gaacgaaugu     2280

uaagacuauc auuaaauaua gauccugaug ccaaaguaga agaagaacca gaagaagaac     2340

cagaagaaac ggcagaagau acaacagaag acaccgaaca agacgaggau gaggaaaugg     2400

acguaggaac ugaugaagaa gaagaaacag caaaagaaag cacugcagaa aaagaugaac     2460

uauaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  3678
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt12)

<400>  3678
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcaa       60

gagaacuaag agcauuacua uuauggggcc gccgacuaag accucucuua agagcuccag      120

cacuagcagc cguaccaggc ggaaagccca uacuaugucc aaggagaaca acugcacaac      180

uaggaccaag aagaaauccu gcuuggaguc ugcaagcagg uaggcuuuuc uccacacaaa      240

cagcugaaga caaagaagaa cccuuacauu caauaauauc uaguacagaa ucuguucaag      300

gaaguaccuc aaaacaugaa uuucaagcag aaacaaaaaa acuacuagac auaguagcac      360

gaucacuaua uagugaaaaa gaaguuuuua uaagagaauu aauaaguaac gccucagaug      420

cacuagaaaa auuacgacac aaauuaguaa gcgaugguca agcuuuacca gaaauggaaa      480

uacauuuaca aacuaacgcu gaaaaaggaa ccauuacaau acaagauaca gguauaggaa      540

ugacacaaga agaacuuguu aguaaucuag gaacaauagc ucgaucagga ucaaaagcau      600

ucuuagacgc auuacaaaac caagcagaag cuagcucgaa aauaauuggu caauuuggag      660

uaggauuuua uucagcauuc augguugcag acaggguaga aguauauuca cguagcgcug      720

caccaggauc auuagguuac caauggcuau cagacgguuc aggcguuuuc gaaaucgcag      780

aagcaucagg aguaagaaca ggaacaaaaa uaauaauaca ccuaaaaagu gauuguaaag      840

aguucucuag ugaagcaaga guuagagaug uaguaacaaa auauucuaau uuuguaucgu      900

uuccacuaua cuuaaaugga cgaagaauga auacacuaca agcaauaugg augauggauc      960

caaaagaugu acgagaaugg caacaugaag aauucuacag auacguugca caagcacaug     1020

acaaaccaag auauaccuua cauuauaaaa ccgacgcacc uuuaaauaua agaucaaucu     1080

uuuauguucc agacaugaaa cccucuaugu ucgacguauc aagagaacua ggaaguagug     1140

uggcccuuua uucaagaaaa guccuaauuc aaacaaaagc aacagauaua uuaccuaaau     1200

gguugagauu uaucagagga guaguagauu cagaagacau cccauuaaau cuaaguaggg     1260

agcuauuaca agaaucagca uuaauaagga aacuaagaga cguuuuacaa caaagacuua     1320

uaaaauuuuu uauagaucaa agcaaaaaag augcagaaaa auacgcuaaa uuuuucgaag     1380

acuaugggcu auuuaugaga gagggaauag uaacagcaac ugaacaagaa guaaaagaag     1440

acauugcaaa acuacucaga uaugaaagua gugcucugcc uagcggucaa uuaacaaguc     1500

ugucugaaua ugcuucacga augagggccg gaacaagaaa uauauacuac uuaugcgcac     1560

caaaccgaca cuuagcagaa cauucacccu auuaugaggc aaugaaaaag aaagacacag     1620

aaguucuauu uugcuuugaa caauucgacg aacucacuuu acuacaccua agagaauuug     1680

acaaaaaaaa auuaauuagc gucgaaacag auauaguggu ugaccauuau aaagaagaaa     1740

aauuugagga uagaucucca gcggccgaau gccuuucaga aaaagaaaca gaagaacuua     1800

uggccuggau gagaaacguu cuagggucua gaguaacaaa ugugaaagua acauuaagau     1860

uagacacaca uccggcaaug guaacaguuc uagaaauggg agcggcaaga cacuuuuuaa     1920

gaaugcaaca auuggcaaaa acacaggaag aaagagcaca auuauuacag ccaacacucg     1980

aaaucaaccc uagacacgca uuaauaaaaa aacuaaauca acuaagagca ucagaaccag     2040

gacuugcaca auugcuaguc gaucaaauau acgaaaaugc aaugauagca gcaggauuag     2100

uagaugaucc acgagcgaug guaggacgac uaaaugaguu auuaguaaaa gcauuagaaa     2160

gacacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  3679
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt12)

<400>  3679
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

aaauaucauc acuaccaaca caacuauuca aaugcugcuu cugcgacuuc cuaaaaguaa      120

aaaugcacac aaugucauca ucacaccuau ucuaccuagc acuaugcuua uuaacauuca      180

caucaucagc aacagcagga ccagaaacac uaugcggagc agaacuagua gacgcacuac      240

aauucguaug cggagacaga ggauucuacu ucaacaaacc aacaggauac ggaucaucau      300

caagaagagc accacaaaca ggaauaguag acgaaugcug cuucagauca ugcgaccuaa      360

gaagauuaga aauguacugc gcaccacuaa aaccagcaaa aucagcaaga ucaguaagag      420

cacaaagaca cacagacaug ccaaaaacac aaaaagaagu acaccuaaaa aacgcaucac      480

gaggaucagc aggaaacaaa aacuacagaa uguaaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  3680
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt12)

<400>  3680
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

uaccaauggg aaaaucaaug cuaguacuac uaacauuucu agcauucgca ucaugcugua      120

uagcagcaua cagaccauca gaaacacuau gcggaggaga auuaguagau accuuacaau      180

uuguaugugg agacagagga uucuauuucu caagaccagc aucaagagua ucaagaagau      240

caagaggaau aguagaagaa ugcuguuuca gaucauguga cuuagcauua cuagaaacau      300

auugcgcaac accagcaaaa ucagaacgag auguaucaac accaccaaca guacuaccag      360

auaacuuucc aagauaccca guaggaaaau uuuuccaaua cgauacaugg aaacaaucaa      420

cacaaagacu aagaagagga cuaccagcac uacuaagagc aagaagagga cacguacuag      480

caaaagaacu agaagcauuu agagaagcaa aaagacauag accacuaauu gcauuaccaa      540

cacaagaucc agcacacgga ggagcaccac cagaaauggc aucaaacaga aaauaaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  3681
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt12)

<400>  3681
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

cauucucaac aucagcauuc ggaccaguag cauucucacu aggacuacua cuaguacuac      120

cagccgcauu cccagcacca guaccaccag gagaagacuc aaaagacguu gcagcaccac      180

acagacaacc ccuaacaucc ucagaaagaa uagacaaaca aauaagauac auacuagacg      240

gaauaucagc acuaagaaaa gaaacaugca acaaaucaaa caugugcgaa ucaucaaaag      300

aagcacuagc cgaaaacaac cuaaaccuac caaaaauggc agaaaaagac ggaugcuucc      360

aaucagguuu caacgaagaa acaugccuag uaaaaauaau aacaggacuc cuagaauucg      420

aaguauaccu agaauaccua caaaacagau ucgaaucauc agaagaacaa gcaagagcag      480

uacaaauguc aacuaaagua cuaauacaau uccuacaaaa aaaagcaaaa aaccuagacg      540

caauaacaac accagaccca acaaccaacg caucacuacu cacaaaacua caagcacaaa      600

accaauggcu acaagacaug acaacacacc uuauacuacg aucauucaaa gaauuccucc      660

aaucaucccu ccgagcccuc agacaaaugu aaggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  3682
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt12)

<400>  3682
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccau       60

uacuaugguu aagaggauuu uuauuagcua guugcuggau aauagucaga ucaagcccaa      120

cgccaggaag cgaaggacac ucagcagcuc cagacugucc aaguugugca uuagcagcau      180

uaccuaaaga uguuccuaau ucacaaccag aaaugguaga agcaguaaaa aaacauauau      240

uaaauauguu acacuuaaaa aaaaggccag acguaacaca accaguucca aaagcagcau      300

uauugaacgc aauaagaaaa uuacacguag gaaagguagg ggaaaacgga uauguagaaa      360

uagaagacga uauaggaaga agagcagaaa ugaaugaacu aauggaacaa acaagugaaa      420

uaauaacuuu cgcagaaagc ggaacagcaa gaaaaacacu acacuuugaa auaaguaaag      480

aagggagcga uuuaucagua guagaaagag cagaaguaug guuauuucua aaaguaccaa      540

aagcaaauag aacuagaaca aaaguaacaa uaagacuauu ccaacaacaa aaacauccac      600

aaggaucuuu agauacugga gaagaagcgg aagaaguagg acuuaaagga gaaagaucag      660

aacuacuauu aagugaaaaa guaguagaug cacgaaaaag uacauggcau guauuuccag      720

uauccaguuc aauacaaaga cuauuagauc aaggaaaaag cagcuuagac guuagaauag      780

cuugugaaca gugucaagaa ucaggagcaa guuuaguuuu acuaggaaaa aaaaaaaaaa      840

aagaagaaga gggagaaggu aaaaaaaaag gugggggaga aggaggagca ggagcugaug      900

aagaaaaaga acaaucacau agacccuucu uaaugcuaca agcaagacaa ucagaagauc      960

auccacauag aagaagacga agaggcuuag aaugugaugg aaaaguaaau auauguugca     1020

aaaaacaauu cuuuguauca uuuaaagaua uaggauggaa ugauuggaua auugcaccca     1080

gcgguuauca ugcaaacuau ugugaaggag aaugcccauc acacauagcg ggaacuagug     1140

gaaguucauu aagcuuucac ucaacuguga uaaaucauua ucguaugaga ggccauucgc     1200

cguuugcaaa uuuaaaauca uguuguguac caacaaaacu aagaccaaug aguauguuau     1260

auuaugacga uggacaaaau auaauaaaga aagacauaca aaauaugaua guagaagaau     1320

guggauguag uuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  3683
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt12)

<400>  3683
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacg       60

gauuaccugg cagagcuuug ggagcagcau gucuauuacu auuagcugca ggaugguuag      120

gaccagaagc auggggaucg ccaacaccac caccaacacc agcugcacca ccaccaccac      180

caccuccugg uucaccaggc gggucucaag acaccuguac aagcugugga ggcuuuagga      240

ggccagaaga acuaggaaga guagauggag acuuuuuaga agcuguaaaa agacauauac      300

uuaguagacu ccaaaugaga ggaagaccaa auauaacaca ugccguacca aaagcugcaa      360

ugguaacugc acuucgaaaa cuacaugcag gaaaaguaag agaagaugga aggguagaaa      420

uaccucaucu agauggacau gcaucaccag gagcagaugg acaagaaaga guaucagaaa      480

uaauaucuuu ugcagaaaca gauggauuag cgucaucaag aguaagauua uacuuuuuca      540

uaucaaacga aggaaaucaa aauuuauuug uaguacaagc gagcuuaugg uuauaucuaa      600

aauuauuacc cuauguuuua gaaaaaggau caagacgaaa aguaagagua aaaguuuauu      660

uucaggaaca aggacacgga gacagaugga auaugguaga aaagagagua gacuuaaaaa      720

gaaguggaug gcauacauuc ccacuaacug aagcaauuca agcacuauuu gaaagaggag      780

aaagaagauu aaaccuagau gugcaaugug auucuuguca agaauuagca gucguaccag      840

uauuuguuga uccaggagaa gaaagucaua gaccauuugu gguaguucaa gcaagauuag      900

gagauaguag acauaggaua agaaaaagag gauuagaaug ugauggaagg acaaauuuau      960

guuguagaca acaauucuuu auugacuuua gauuaauagg auggaaugau uggauaauag     1020

cacccacagg auauuauggg aauuauugug aaggaaguug uccagcauac uuagcaggag     1080

uacccggauc agcaaguucc uuucauacag caguugucaa ccaauaucga augagagggu     1140

uaaauccagg uacaguaaac ucauguugua uaccaaccaa acuaaguacu augagcaugu     1200

uauauuuuga ugaugaauau aacauuguaa aacgagaugu accaaacaug auaguagaag     1260

aauguggaug ugcauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  3684
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt12)

<400>  3684
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcau       60

uaagaguauu acugcugaca gcuuugacuc uaugucacgg cuucaaccua gacacagaaa      120

augcuaugac cuuucaagaa aaugcacgag guuucggaca gucugucguc caacuacaag      180

gaucaagggu uguagucggc gcaccccaag aaauuguagc agcaaaucaa agaggcuccu      240

uauaucaaug cgacuacuca acagguagcu gcgaaccaau acgucuucaa guucccguug      300

aagcagugaa caugucacuu gguuuaaguu uagcagcuac aacaagccca ccucaacuau      360

uagcuugcgg ccccacagua caccaaaccu guagcgaaaa uacuuauguu aaaggauugu      420

guuuccuauu cgguuccaau uuacgacagc aaccucaaaa auucccugaa gcacuucgug      480

gaugccccca agaagauagc gauauagcau uuuuaaucga cgguuccgga uccauaauac      540

cccaugacuu ccggagaaug aaagaauuug uaaguacagu gauggaacaa uugaagaaau      600

cuaaaacucu auuuucucug augcaauaua gugaagaauu uaggauacac uuuacuuuua      660

aagaauuuca aaacaaccca aauccgagau cguuaguaaa accgauuacu cagcuuuuag      720

gacgaacuca uacagcuacu ggaauacgua aaguaguaag agaacucuuc aacauaacaa      780

auggcgcacg uaaaaaugcu uuuaagauau uaguaguaau uacagacgga gaaaaauucg      840

gagauccucu aggauacgaa gacguaauac cagaagcuga uagagagggc guaauaagau      900

auguaauagg cguuggagau gcauucagaa gcgagaaaag cagacaagaa uugaacacaa      960

ucgcaucuaa acccccacga gaucauguau uccaggucaa uaauuucgaa gcucuaaaaa     1020

caauacaaaa ccaacugaga gagaaaauau uugcaauaga agggacacaa acaggcucau     1080

cgagcucauu ugaacaugaa augagccaag aaggauuuuc agcagcaaua accucaaacg     1140

gaccacuauu auccacuguu ggaaguuaug auugggcagg gggagucuuc uuauacacgu     1200

ccaaagaaaa aucuacauuu auaaacauga ccagaguuga cagugacaug aaugacgcuu     1260

accucggcua ugcagcagcu auuauacuac gaaauagagu acaaucacuu guuuuagggg     1320

caccacggua ccaacauauu ggucuaguug ccauguuccg acaaaauaca ggaauguggg     1380

aaucaaaugc caauguaaaa ggaacacaaa uaggagcuua uuucggcgca ucauuauguu     1440

ccguagaugu agacucaaac ggaucaacag auuuaguccu gauuggugcc ccacauuauu     1500

augaacaaac aagagguggu cagguaagug uuuguccgcu cccacgaggu agagcccgau     1560

ggcaaugcga ugcuguacuu uauggagaac aaggacagcc auggggaaga uucggggcag     1620

cacuaacagu acuaggugac gugaaugggg auaaacuaac cgauguagca auaggugcac     1680

caggcgaaga agacaauaga ggagcaguau acuuauuuca cggaacauca ggcucaggaa     1740

uaagcccuuc gcacucacaa agaaucgcug gcaguaaauu aagcccucgc cuucaauacu     1800

uuggacaguc gcuuagugga ggccaagauc uaacaaugga cggauuaguu gaccuaacgg     1860

uaggagcaca gggucauguc cuacuauuac gaucccaacc uguuuugcgu gucaaagcaa     1920

uuauggaguu caauccaaga gaaguagcac gaaauguuuu ugaaugcaau gaucaaguag     1980

uuaaaggcaa agaagcugga gaaguacggg uuugucuaca uguacaaaaa uccacacgag     2040

accgucuacg cgaaggucaa auacaaucag uaguuaccua ugaucuugca cuugacucug     2100

gaagaccuca cucuagggcu guauuuaaug aaacuaaaaa uuccacgaga cgacaaacac     2160

aaguacuagg ucuuacccaa acuugugaaa ccuuaaagcu acaacuccca aauugcauag     2220

aagauccagu aaguccaaua guacugagac ucaauuucuc ccuugucgga accccucuaa     2280

gcgcguucgg aaacuuacga ccaguacuag cagaagacgc acagagacuu uuuacugcac     2340

uuuuuccauu cgagaaaaau ugcggaaacg acaauauaug ucaagacgac uuaucuauaa     2400

cauuuucauu caugucauua gauuguuugg uaguuggagg uccccgggag uucaauguca     2460

caguaacagu cagaaaugau ggagaagauu cuuaccgaac acaaguuacc uuuuucuuuc     2520

cacuugauuu aagcuaccga aaagucucua cacuacagaa ccaacgaagu caacgcucgu     2580

ggagacuugc augugaaagc gcuucuucaa cugaaguuuc aggugcuuug aaaucaacau     2640

cauguaguau aaaccauccc auuuuuccgg aaaauucuga aguuacauuu aacauuacgu     2700

ucgaugucga uucaaaggcu ucucuuggua auaaauuacu auugaaagca aaugucacau     2760

ccgaaaauaa uaugccaagg accaacaaaa cagaguucca acuugaauua ccuguaaaau     2820

augcugucua caugguugua acaucacaug gaguaucuac caaauaucuc aauuuuacag     2880

caucugaaaa uacuucacga guaaugcaac accaauacca aguaucaaau uuaggacaac     2940

gaucacuccc aauuagucuu guuuuucuag ucccagucag auugaaucaa acaguaaucu     3000

gggauagacc acaaguaaca uuuucugaaa acuuaagcag uacaugucau acaaaagaac     3060

gcuuaccauc ccauuccgac uuucuugcug aauuaagaaa agcaccuguc gucaauugcu     3120

caaucgcagu gugccaacga auacaaugug acauucccuu cuuuggcaua caagaagagu     3180

uuaacgcuac acuaaagggc aauuuauccu uugacuggua cauaaaaaca ucacauaauc     3240

aucuauuaau uguaucaaca gcagaaauau uauuuaacga cagcguauuc acacuucucc     3300

ccgggcaagg agcuuuuguc agaagucaaa cagaaacaaa aguagaacca uucgaaguuc     3360

caaaccccuu accucucaua guagguuccu cgguaggugg auuacuacug cuugcauuaa     3420

uuacagccgc uuuauauaaa cuuggauucu uuaagagaca auauaaggau augaugucug     3480

aaggaggacc uccuggcgca gaaccacaau aaggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  3685
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt12)

<400>  3685
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguucu       60

cacuuaaaac ucucccauuc uuacuacuac uacacgucca aauaucaaaa gccuuccccg      120

uauccucaaa agaaaaaaau acuaaaacag uucaagacua ccucgaaaaa uucuaccaac      180

uaccuucaaa ccaauaccaa ucaacaagaa aaaaugguac uaaugucaua gucgaaaaau      240

uaaaagaaau gcaaagauuu uuuggacuua acguuacagg aaaaccuaac gaagaaaccc      300

uagacaugau gaaaaaacca cgaugcggag ucccagacuc aggaggcuuc augcuaacac      360

caggaaaucc aaaaugggaa cguacaaacu uaacauaccg cauacgaaac uacaccccac      420

aacuaaguga agcagaagua gaacgcgcca uaaaagacgc cuucgaacua uggucaguag      480

caagcccacu cauauuuacu agaauaucac aaggugaagc ugauaucaau aucgcauuuu      540

accaacgaga ccacggcgau aacucaccau ucgacggccc aaauggaaua cuagcccacg      600

cauuccaacc aggacaagga auaggaggug acgcacacuu cgacgcagaa gaaaccugga      660

caaacacauc agcaaacuau aacuuauuuc uagucgccgc acacgaauuc ggacacucac      720

uagguuuagc acacucauca gacccaggcg cacuaaugua ucccaacuau gcauucagag      780

aaaccucaaa uuauucauua ccucaagacg auauagacgg aauucaagca auauauggac      840

uuucuucaaa uccaauacaa ccaacaggcc cuucaacccc aaaacccugu gaucccucac      900

uaacauucga cgcaaucaca acucuacgag gagaaauuuu auucuuuaaa gacagauauu      960

uuuggagaag acacccacaa cuacaaagag uagaaaugaa cuucauaagc uuauucuggc     1020

caucacuacc aacaggcauu caagcagcau acgaagacuu cgauagagac cuaauauucu     1080

uauuuaaagg aaaccaauau ugggcacuau cagguuacga cauacuacaa ggauacccaa     1140

aagacauauc caauuaugga uucccaucau caguacaagc aauagacgca gcaguauucu     1200

auagaucaaa aaccuacuuc uucguaaaug aucaauucug gagauacgac aaccaacgcc     1260

aauucaugga acccggauau cccaaaucaa uaucaggagc auucccagga auagaaucaa     1320

aaguagacgc uguauuccaa caagaacauu ucuuucaugu cuucuccgga cccagguacu     1380

acgcauuuga uuuaauagcc caaagaguaa cacgaguagc aagaggaaau aaaugguuga     1440

auuguagaua cggauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  3686
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt12)

<400>  3686
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

uuuggcaacc cuuaguuuua guuuuacuag uauuaggaug cugcuucgca gcuccuagac      120

aaaggcaauc aacacuuguu cucuuuccag gagacuuacg aacaaaucua acagauagac      180

aacuagcaga agaauacuua uauagauaug gauauaccag aguugcagaa augagaggag      240

aaaguaaauc guuaggaccu gcccuacuac uucuucaaaa acaauuauca uuaccagaaa      300

caggagaacu agauucugcu acacuaaaag caaugagaac cccuagaugc ggaguuccag      360

auuuaggccg auuucaaaca uuugaaggag accuaaaaug gcaccaucau aauauaacuu      420

auuggauaca aaauuacucu gaagacuuac cgagagccgu aauagacgau gcauucgcua      480

gagcauuugc uuuaugguca gcaguuacac cccuaacauu uacuagagua uauucaagag      540

augcugauau aguaauucaa uuuggagucg cagaacaugg ugauggauau ccauuugaug      600

gaaaagacgg auuauuagcc cacgcauucc caccuggucc aggcauucaa ggagaugcac      660

auuucgacga ugacgaauua uggagcuuag gaaaaggagu aguaguaccu acacgcuuug      720

ggaaugcuga uggagcagca ugccauuucc cauuuauuuu cgaagguaga ucauacucug      780

caugcacuac agauggaaga uccgauggau uaccuuggug cagcacaaca gcuaauuaug      840

acacugauga cagauuuggu uuuuguccau ccgaaagacu uuacacacaa gacggaaaug      900

cagaugguaa accaugccaa uuuccuuuua uauuucaggg acaaucauau ucagcuugua      960

caacagaugg gagaagugau ggauaccgcu ggugugcaac cacugccaau uaugauagag     1020

acaagcuauu uggauucugu ccuacaagag cagacucgac uguaaugggu ggaaauucag     1080

ccggagaacu augugucuuc ccauuuacau uuuuagguaa agaauacucu acauguacuu     1140

cagaaggccg uggugaugga agacuuuggu gugcaacaac aucaaauuuc gacucugaca     1200

aaaaaugggg auuuugucca gaucaaggau acagcuuauu ucuaguugca gcacacgaau     1260

uuggacaugc acuagguuua gaucacaguu caguaccaga agcauuaaug uauccaaugu     1320

auagauuuac cgaagggccu ccccuucaca aagaugacgu uaauggaaua agacacuuau     1380

acggacccag accugaaccu gaaccaagac cuccuacuac aacuacucca caaccaacag     1440

ccccaccaac aguaugccca acgggaccgc caacaguaca cccaagcgaa agaccaacug     1500

cuggaccaac aggaccaccc agugcagguc caacuggucc accuacagca ggcccaucua     1560

cugcaacaac agucccauua aguccagugg acgaugcaug caacguuaac auauucgacg     1620

caauugcaga aauuggaaau caauuauauc uuuuuaaaga uggaaaauac uggagguucu     1680

cagaaggaag agguucaaga ccacaagguc cauuucuuau agcugauaaa uggccagcuc     1740

uccccagaaa auuagacuca guauucgaag aacgauuaag uaaaaaauua uucuucuuuu     1800

caggcagaca aguuugggua uauacuggug caaguguacu cggaccaaga agacuugaua     1860

aauuaggcuu aggggcagac guugcacaag uaacuggagc ccuaagaucc ggucgaggaa     1920

aaauguuauu auucucagga agaagauuau ggagauuuga uguuaaagca caaaugguug     1980

auccaagauc agcaucagaa guagacagaa uguuuccagg cguaccacua gauacucaug     2040

acguauuuca auaucgggaa aaagcguacu uuugucaaga uagauuuuau uggagaguuu     2100

cuucaagauc agaauuaaac caaguagauc aaguuggaua uguaacauau gauauccuac     2160

aaugcccaga agacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  3687
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt12)

<400>  3687
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

caggaguacu agcagcauuc uuauucuuau cuuggaccca cuguagagca cuaccucuac      120

cuagcggagg agaugaagau gaccucucag aagaagaccu acaauucgca gaaagauauc      180

uacgaucuua uuaccaccca acaaacuuag caggaauacu aaaagaaaac gcugcaucau      240

caaugacaga aagacuaaga gaaaugcaau cauuuuucgg acuagaagua acaggaaaau      300

uagacgacaa cacauuagac guaaugaaaa aaccaagaug cggaguacca gaugucggag      360

aauacaacgu cuucccaaga acauuaaaau ggagcaaaau gaaccuaaca uauagaauag      420

uaaauuacac acccgacaug acacacucag aaguagaaaa agcauuuaaa aaagcauuca      480

aaguaugguc cgaugucaca ccccuaaacu ucacaagauu acaugacgga auagcagaca      540

uaaugauauc uuucggaaua aaagaacacg gugacuucua cccuuucgac ggaccaucag      600

gacuauuagc acacgcauuc ccacccggac caaauuacgg aggagaugca cacuuugacg      660

augaugaaac uuggacauca ucaucaaaag guuauaacuu auuucucgua gcugcccacg      720

aauucggaca cucacuaggg cuagaccaca gcaaagaccc cggagcauua auguuuccaa      780

uuuauacaua uacaggaaaa agucacuuua ugcuaccgga cgacgacgua caaggcauac      840

aaucacucua cgguccagga gacgaagacc caaacccaaa acaccccaaa acaccagaua      900

aaugcgaccc aucacuauca uuagaugcaa uaacaucauu aagaggagaa acuaugauuu      960

ucaaagacag auucuucugg agguuacacc cccaacaagu agaugcagaa cucuuucuaa     1020

caaaaucauu uuggccagaa uuaccaaaua gaauugacgc ugcauacgaa cacccaucac     1080

acgaccuaau auuuauauuc agaggaagaa aauucugggc cuuaaacgga uaugacauac     1140

uagaaggaua cccaaaaaaa auaucagaau uaggucuacc caaagaagua aaaaaaauau     1200

cagcagccgu ccacuucgaa gacacuggaa aaacauuacu cuuuaguggc aaccaaguau     1260

ggagauauga cgauacaaac cacauaaugg auaaagacua cccaagauua auagaagaag     1320

acuuuccagg aauuggagac aaaguagacg ccguauacga aaaaaaugga uacauauacu     1380

uuuucaacgg accaauucaa uucgaauauu ccauaugguc aaaccgaaua guuaggguaa     1440

ugccagcaaa cuccauauua ugguguuaag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3688
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt12)

<400>  3688
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

caccaaauac aacagaagac uaugacacaa cuacagaauu cgacuauggc gacgccacac      120

caugccaaaa aguaaacgaa agagcauucg gcgcacaauu auuaccaccu uuauacucau      180

uaguauucgu aauaggauua guaggaaaca uacuaguagu auuaguacua guacaauaca      240

aaagacuaaa aaacaugaca uccauauacc uacuaaacuu agcaauaucu gaccuacuau      300

uccuauucac ucuaccauuc uggaucgacu auaaacuaaa agaugacugg guuuucggug      360

acgcaaugug caaaauccuc ucaggauuuu acuacacagg auuauacagc gaaaucuuuu      420

ucaucauacu auuaaccauc gaccgauacc uagccauagu acacgcagua uucgcacuca      480

gagccagaac aguaacuuuc ggcguaauaa caucaauaau aaucugggca uuagccauac      540

ucgcaucaau gccaggacua uacuucucaa aaacacaaug ggaauucacc caucacacau      600

gcucauuaca cuucccucac gaauccuuaa gagaauggaa acuauuucaa gcccuaaaau      660

uaaacuuauu cggacuagua cuaccuuuac uaguaaugau aaucuguuac acaggaauua      720

uaaaaauacu acucagaaga cccaacgaaa aaaaaucaaa agccguaaga uuaauauucg      780

uaauaaugau aauuuucuuc uuauucugga caccauacaa cuuaacaaua cucauuuccg      840

ucuuccaaga cuucuuauuc acucacgaau gcgaacaauc aagacaucua gaccuagcag      900

uccaagucac cgaaguaaua gcauacacac acugcugcgu aaacccagua auuuacgcau      960

ucguaggaga acgauucaga aaauaccuua gacaacuuuu ucacagaaga guagcagucc     1020

accuugucaa auggcuacca uuuuuaucug uagacagacu agaaagagua ucuucaacau     1080

caccaucuac aggagaacac gaacucucug ccggcuuuua aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  3689
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt12)

<400>  3689
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcgaa       60

cacuagccug ccuauuacua cuaggaugcg gauaccuagc acacguacua gcagaagaag      120

cagaaauacc aagagaagua auagaaagac uagcaagauc acaaauacac aguauaagag      180

accuacaaag acuacuagaa auagacucag uaggaucaga agacucacua gacacaucac      240

uaagagcaca cggcguacau gcaacaaaac acguacccga aaaaagacca uuaccaauaa      300

gaagaaaaag aagcauagaa gaagccguac cagcaguaug uaaaacaaga acaguaauau      360

acgaaauacc aagaagccaa guagacccaa caucagccaa cuucuuaaua uggccaccau      420

gcguagaagu aaaaagaugc acaggaugcu gcaacacaag cagcgucaaa ugccaaccaa      480

guagaguaca ccaucgauca guaaaaguag caaaaguaga auacgucaga aaaaaaccaa      540

aacuaaaaga aguacaagua agacucgaag aacaccuaga augcgcaugc gccacaacaa      600

gccuaaaccc agacuacaga gaagaagaca caggaagacc aagagaauca ggaaaaaaac      660

gaaaaagaaa aagacuaaaa ccaacuuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  3690
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt12)

<400>  3690
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaca       60

gaugcugggc acuauuccua ucauuaugcu guuacuuaag acuaguauca gcagaaggag      120

auccaauacc agaagaauua uacgaaaugu uaagugauca cucaauaaga agcuuugacg      180

auuuacaaag acuacuacau ggagauccag gagaagaaga cggagcagaa cuugaucuaa      240

auaugacaag aucacacagu ggaggagaau uagaaucacu agccagagga agaagaaguc      300

uaggaucacu cacaaucgca gaaccagcaa ugauagcaga auguaaaaca agaacagaag      360

ucuucgaaau cucaagacga cuaauagaca gaacaaaugc aaacuucuua guauggccac      420

caugcguaga aguacaaaga ugcucaggau gcugcaauaa caggaacgua caauguagac      480

caacacaagu acaacuaaga cccgugcaag uaagaaaaau agaaauagua agaaaaaaac      540

caaucuuuaa aaaagcaaca guaacacuag aagaucaucu agcaugcaaa ugcgaaacag      600

uagcagcugc aagaccagua acaagaucac caggaggaag ccaagaacaa agagcaaaaa      660

cgccacaaac aagaguaaca auaagaacag uuagaguaag aagaccacca aaaggaaaac      720

auagaaaauu caaacacaca cacgauaaaa cagcauuaaa agaaacauua ggagcauaag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  3691
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt12)

<400>  3691
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucau       60

uauucggauu auuacuuuua acaucugcau uagcaggaca aagacaagga acacaagcag      120

aaucaaaccu aucaagcaaa uuucaauuuu caucaaauaa agaacaaaau ggcguacaag      180

auccacaaca cgaaagaaua auaacaguaa gcacuaacgg aucaauacac agcccccgau      240

ucccacauac auacccaaga aacacaguau uaguauggag auuagucgcc guagaagaaa      300

auguauggau acaacuuaca uucgaugaaa gauucggauu agaagacccc gaagacgaca      360

uaugcaaaua cgacuucgua gaaguagaag aacccucaga cggaacaaua uuaggucguu      420

ggugcggauc aggaacagua ccaggaaaac aaauaaguaa aggaaaccaa auaagaauuc      480

gauucguauc agaugaauac uuuccaucag aaccaggauu cugcauccau uacaauauag      540

uaaugccaca auuuacagaa gcaguaucac caagcguauu accaccauca gcccuaccuc      600

uagacuuauu aaauaacgca auaacagcau uuagcaccuu agaagacuua auacgauacu      660

uagaaccaga acgauggcaa cuagaccuug aagaccuaua cagaccaaca uggcaauuac      720

uaggaaaagc auucgucuuu ggcagaaaau caagaguagu agaucuaaac cuacuaacag      780

aagaaguaag auuauacagu ugcacaccua gaaacuucuc aguaagcaua agagaagaac      840

uaaaaagaac agacaccaua uucuggccag gaugccuacu aguuaaaaga ugcggaggaa      900

auugcgcaug uugcuuacac aacuguaacg aaugccaaug cguacccuca aaaguaacaa      960

aaaaauacca cgaaguacua caauuaagac caaaaacagg aguaagagga cuccacaaau     1020

cacuuacaga cguagcacua gaacaccacg aagaauguga cugcguaugc agaggcucaa     1080

ccggaggaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  3692
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt12)

<400>  3692
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaua       60

gauuaauauu cguauacaca cuaauaugug caaacuucug cucaugcaga gacaccagug      120

caacacccca aagcgcauca auaaaagcac uacgaaacgc aaacuuaaga agagacgauc      180

uauauagaag agaugaaaca auacaaguaa aaggaaacgg auacguacaa ucaccacgau      240

uuccaaauuc auacccacga aaccuauuau uaacauggcg acuacacuca caagaaaaua      300

caagaauaca acuugucuuc gacaaccaau ucggacuaga agaagcagaa aaugacauau      360

gcagauauga cuucguagaa guagaagaca uaucagaaac uucaacaaua auaagaggaa      420

gauggugugg acacaaagaa gucccaccaa gaauaaaauc aagaacaaac caaauaaaaa      480

uaaccuucaa aucagaugac uacuucguag caaaaccggg cuuuaaaaua uacuauagcc      540

uauuagaaga cuuccaacca gcagcagcau cagaaaccaa cugggaauca guaacaagcu      600

caauaucugg aguaucauac aacucaccau caguaacaga uccaacacua auagcagacg      660

cauuagacaa aaaaauagcc gaauucgaca caguagaaga ucuacuaaaa uacuucaacc      720

cagaaucaug gcaagaagac cuagaaaaca uguaccuaga cacaccaaga uacagaggaa      780

gaucauacca ugacagaaaa aguaaaguag accuagacag acuaaacgac gaugcaaaaa      840

gauacagcug cacaccaaga aauuacucag uaaacauaag agaagaacua aaacuagcaa      900

acguaguauu cuucccaaga ugcuuauuag uacaaaggug cggaggaaau uguggaugcg      960

gaacaguaaa cuggagaucc uguacaugca acucaggcaa aacagucaaa aaauaccacg     1020

aaguacuaca auucgaacca ggacacauaa aaagaagagg cagagcaaaa acaauggcac     1080

uaguagacau acaacucgau caccacgaaa gaugcgacug uauaugcuca agcagaccac     1140

cacgauaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  3693
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt12)

<400>  3693
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguaa       60

cacacucaaa auucccagca gcaggaaugu cacgaccucu agacacauca uuacgacuaa      120

aaacauucuc aucaaaaucu gaauaccaac uaguaguaaa cgcaguaaga aaauuacaag      180

aaucaggauu cuacugguca gcaguaacag gaggagaagc aaaccuacua uuaucagcag      240

aaccagcagg aacauuccua auaagagacu caucagacca aagacacuuc uuuacacuau      300

caguaaaaac ccaaucugga acaaaaaacc uacgaauaca augugaagga ggauccuucu      360

cucuacaauc agacccaaga ucaacacaac caguacccag auuugacugc guacuaaaau      420

uaguacacca cuacaugccc ccacccggag caccaucauu cccaucaccc ccaacagaac      480

ccucaucaga aguaccagaa caaccaucag cacaaccacu accaggcuca ccaccaagaa      540

gagcuuauua cauauacucc ggaggagaaa aaauaccacu aguucuauca agacccuuau      600

caucaaacgu agccacacua caacaccuau gcagaaaaac aguaaacgga cacuuagacu      660

cauacgaaaa aguaacacaa cuuccaggac caauaagaga auucuuagau caauacgacg      720

caccauuaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  3694
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt12)

<400>  3694
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguac       60

caucagcagg acaauuagca uuauucgcau uaggaauagu auuagcagca ugucaagcau      120

uagaaaauuc aacaucacca uuaucagcag acccaccagu agcagcagca guaguaucac      180

auuuuaauga uugcccagau ucacauacac aauucugcuu ucauggaaca uguagauuuu      240

uaguacaaga agauaaacca gcauguguau gucauucagg auauguagga gcaagaugug      300

aacaugcaga uuuauuagcc guaguagcag caucacaaaa aaaacaagca auaacagcau      360

uaguaguagu aaguauagua gcauuagcag ucuuaauaau aacaugugua uuaauacauu      420

guugucaagu aagaaaacau ugugaauggu gcagagcauu aauauguaga caugaaaaac      480

caucagcacu auuaaaagga agaacagcau guugucacuc agaaacagua guauaaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  3695
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt12)

<400>  3695
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

caaguggauu aagacuacua ccauuacuau uaccacuauu auggcuacua guauuaacac      120

cuggaagacc agcugcaggc cuaucaaccu gcaaaacaau agacauggaa cuaguaaaac      180

gaaaaagaau agaagcaaua agaggccaaa uacuaucaaa acuaagauua gcaucaccac      240

cuucccaagg agaaguacca ccaggcccac uaccagaagc aguacuagca cuauacaacu      300

ccacaagaga cagaguagca ggcgaaucag ccgaaccaga accagaacca gaagcugacu      360

acuacgcaaa agaaguaacu agaguauuaa ugguagaaac acacaacgaa aucuaugaca      420

aauuuaaaca aucuacacau ucuauauaua uguucuucaa uacaagcgaa uuacgagaag      480

caguacccga accaguacua uuaucaagag cugaacuccg auuacuaaga uuaaaacuaa      540

aaguagaaca acacguagaa cuauaccaaa aauauucuaa uaauucaugg agauaucuua      600

gcaauagauu acuagcacca uccgacucac cugaauggcu aucauuugau guaacaggag      660

uaguacguca auggcuauca cgaggcggag aaauagaagg auuuagauua agcgcucacu      720

gcagcuguga cucaagagac aacacauuac aaguagacau caacggauuc acaacaggaa      780

gaagaggaga ucuagccaca auacacggaa ugaacagacc auuucuacua uuaauggcaa      840

caccacuaga aagagcacaa caucuacaau cuucaagaca cagaagagca uuagacacaa      900

acuacugcuu uucaagcaca gaaaaaaauu gcugcgucag acaauuauau auagauuuca      960

gaaaagauuu aggcuggaaa uggauacaug aaccaaaagg auaccacgca aacuucugcc     1020

uaggaccaug cccauacauu uggucauuag auacccaaua cucaaaaguu cuugcauuau     1080

acaaccaaca caacccugga gcaagugcag caccauguug cguaccccaa gcauuagaac     1140

cacuaccaau aguauauuac guuggccgaa aacccaaagu agaacaacua ucaaacauga     1200

uagucagauc auguaaaugu ucauaaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  3696
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt12)

<400>  3696
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugcguacu cucagccuuc cuaauacuac accuaguaac aguagcauua agcuuaucaa      120

caugcucaac acuagacaug gaucaauuca ugagaaaaag aauagaagca auaagaggcc      180

aaauacuauc aaaacuuaaa uuaacaucac caccagaaga cuaucccgaa ccagaagaag      240

uaccaccaga aguaauauca auauauaacu caacaagaga ccuauuacaa gaaaaagcaa      300

gccgaagagc agcagcaugc gaacgagaaa ggucagacga agaauacuac gccaaagaag      360

uauacaaaau agacaugcca cccuucuucc caucagaaaa ugccauaccc cccacauuuu      420

acagaccaua cuucagaauc guaagauucg acguaucagc aauggaaaaa aacgcaucaa      480

aucuaguuaa agcagaauuc agaguauuca gacuacaaaa cccaaaagca agaguaccag      540

aacaaagaau agaacuauac caaauacuua aauccaaaga ucuaacauca ccuacacaaa      600

gauauauaga cucaaaagua guaaaaacua gagcagaagg cgaauggcua uccuucgacg      660

uaacagacgc cguucacgaa uggcuucacc acaaagaccg aaacuuagga uucaaaauau      720

cacuucacug uccauguugc acauuugucc ccucaaauaa cuacauaauc cccaauaaau      780

cagaagaacu cgaagcaaga uucgccggaa uagacggaac uagcacauau accuccggag      840

accaaaaaac cauaaaaucu acaagaaaaa aaaacucugg aaaaacacca cacuuacuau      900

uaaugcuacu acccucauac cgacucgaau cucaacaaac aaacagacga aaaaaaagag      960

cauuagacgc cgcuuauugu uucagaaaug uacaagauaa cugcugccua cgaccacuau     1020

acauagauuu caaaagagau cuaggcugga aauggaucca ugaaccaaaa ggcuauaacg     1080

caaacuucug cgcuggagca ugcccauacc uauggucauc agacacacaa cauucaagag     1140

uauuaucacu uuacaacacc auaaaucccg aagcaucagc aagccccugu ugcguaucac     1200

aagaccuaga accacuaacc auccuauacu auauaggaaa aacuccaaaa auagaacaac     1260

uaucuaauau gauaguaaaa ucaugcaaau gcucuuaagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  3697
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt12)

<400>  3697
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

ugcacuuaca aagagcccua guaguccuag cuuuacuuaa cuucgcaacc guaucccuaa      120

gccuaucaac uuguacaacc cuagacuuug gacacauaaa aaaaaaacgc guagaagcaa      180

uuagaggaca aauauuaucu aaacuaagau uaaccucacc accagaacca acaguaauga      240

cacauguacc auaccaggua uuagcacuau acaauucaac acgcgaacua cuagaggaaa      300

ugcauggaga aagagaagaa ggaugcacac aagaaaacac agaaucagaa uacuacgcaa      360

aagaaaucca uaaauucgac augauacaag gauuagcaga acacaacgaa cuagcaguau      420

gcccaaaagg aauaacauca aaaguauuua gauucaaugu aucuucaguu gaaaaaaaua      480

gaacuaaccu cuuuagagcc gaauuccgcg uauuaagagu ccccaaccca agcagcaaac      540

gaaacgaaca aagaauagaa cuauuccaaa uacuaaggcc agacgaacac auagcaaaac      600

aaagauauau aggaggcaaa aauuuaccca caagagguac agcagaaugg cuaucauucg      660

auguaacaga uaccguaaga gaauggcuac uaagaagaga aaguaaucua ggccuagaaa      720

uaucaauaca uuguccaugu cacacauucc aaccaaacgg agacauauua gaaaacauac      780

acgaaguaau ggaaauaaaa uucaaaggag uagacaacga agaugaucac ggacgaggcg      840

aucuaggcag auuaaaaaaa caaaaagacc accacaaucc acaccuaaua uuaaugauga      900

uaccaccaca cagacuagac aauccaggcc agggaggcca aagaaaaaaa agggcacuag      960

acaccaacua cugcuucaga aaccuagaag aaaacugcug cguaagacca cuauacauug     1020

acuucagaca agaccuaggc uggaaauggg uccaugaacc aaaaggauac uacgccaacu     1080

uuugcucagg accaugccca uaccucagau cagcagacac aacccacuca acaguauuag     1140

guuuauacaa cacauuaaac ccagaagcaa gugccucccc uuguugcgua ccacaagacc     1200

uagaaccauu aaccauauua uauuauguag gacgaacacc aaaaguagaa caacuaucaa     1260

auaugguagu aaaaucaugc aaauguagcu aaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3698
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt12)

<400>  3698
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcuc       60

cuguagccgu augggcagcu cuagccguag gauuagaauu augggcugcu gcccaugcac      120

uaccugccca aguugcuuuu acaccauacg caccagaacc ugguucaaca uguagauuaa      180

gagaauauua ugaucaaacu gcucaaaugu guuguucaaa auguagcccu ggucaacaug      240

ccaaaguauu cuguacuaaa acuucugaua ccguauguga uucaugugag gauucaacau      300

auacacaauu auggaauugg guaccagaau guuuaucaug uggaucucga uguucaucag      360

aucaaguaga aacacaagcu uguacaagag aacaaaauag aauauguacu uguagaccag      420

guugguacug cgccuuauca aaacaagaag gauguagacu augcgcccca cuacgaaaau      480

guagaccagg auuugguguu gcacguccag gaacagaaac aucagacgua guauguaaac      540

caugcgcucc cgguacauuc ucaaauacaa caucauccac cgauauaugu cgaccacauc      600

aaauauguaa uguaguagca auaccaggaa augcaucuau ggacgcagua uguacaucaa      660

caucacccac aagaucaaug gcaccaggug cuguccaucu accacaaccu guuucaacaa      720

gaucacaaca uacacaaccu acacccgaac cauccacagc accaaguacc ucauuucuuu      780

uaccuauggg accaucacca ccugcagaag gaucaacagg agauuuugca cuuccaguag      840

gacuaauagu uggaguaacu gcacuaggau uauuaauaau uggagucgua aauuguguaa      900

uaaugacaca aguaaaaaaa aaaccauuau gcuuacaacg agaagccaaa gucccucauu      960

uaccagcaga caaagcuaga ggaacccaag gaccagaaca acaacaccua cucauaaccg     1020

caccuucauc aucuucauca ucuuuagaau caucugcauc ugcauuagau agaagagcac     1080

ccacaagaaa ucaaccacaa gcaccuggag uugaagcuuc cggggcaggu gaagcucgag     1140

cuucaacagg aucuucagau ucaucuccag guggucaugg aacccaaguu aauguaacuu     1200

gcaucguaaa uguauguuca ucaucagauc acucaucaca auguucauca caagcaaguu     1260

caacuauggg agauacugac ucaagcccau cggaaucacc uaaagaugaa caaguaccau     1320

uuaguaaaga agaaugugca uuuagaucuc aacuugaaac accagaaacu uuauuaggaa     1380

guacagaaga aaaaccacua ccauuaggag uacccgaugc agggaugaaa ccuuccuaag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  3699
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt12)

<400>  3699
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

uaaugaggcu auuuccaugu uuuuuacaau uacuagcagg auuagcauua ccagcaguac      120

caccacaaca augggcauua agugcaggaa auggaaguuc agaaguagaa guaguaccau      180

uucaagaagu auggggaaga ucauauugua gagcacuuga aagauuagua gauguaguaa      240

gugaauaucc aagcgaagua gaacauaugu uuucaccauc auguguaagu uuauuaagau      300

guacaggaug uuguggagau gaaaaucuac auuguguacc aguagaaaca gcaaauguaa      360

caaugcaauu acuaaaaaua agaaguggag auagaccauc auauguagaa uuaacauuca      420

gucaacaugu aagaugugaa uguagaccau uaagagaaaa aaugaaacca gaaagaagaa      480

gaccaaaagg aagaggaaaa agaagaagag aaaaacaaag accaacagau ugccauuuau      540

guggagaugc aguaccaaga agauaaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  3700
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt12)

<400>  3700
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugacag       60

acagacaaac agauacagca ccuucaccaa gcuaucacuu auuaccuggu agaagaagaa      120

caguagaugc agcagcuagu aggggacaag gaccagaacc agcuccagga ggagguguag      180

aaggaguagg ggcaagagga guagcuuuaa aauuauuugu acaacuuuua ggauguagca      240

gguuuggagg agcgguugua agagccggug aagcagaacc gucaggagca gcaagaucag      300

caagcucagg aagggaagaa ccacaaccag aagaagguga agaagaagaa gaaaaggaag      360

aagaaagggg accacaaugg cgacugggag caagaaagcc agguaguugg acaggagaag      420

cagcaguaug cgcagacucu gcaccagcag caagagcacc gcaagcauua gcucgagcaa      480

guggaagggg aggaagagua gcucgaagag gagcagaaga aucaggaccu ccacacaguc      540

caaguaggag aggaagugca agcagggcag gaccagggag agcaagcgaa acaaugaauu      600

uucuauugag uuggguacau uggagccuag cccuauuauu auauuuacau caugcuaaau      660

ggucacaagc agcaccaaug gcagaaggag gaggacaaaa ucaucaugag guagugaaau      720

uuauggaugu auaucaaaga ucauauuguc auccaauaga aacauuaguu gacauauuuc      780

aagaauaucc agaugaaaua gaauauaucu uuaaaccuag cuguguccca uugaugagau      840

guggaggaug uuguaaugau gagggauuag aaugcguacc aacagaagaa aguaacauaa      900

caaugcaaau aaugcgaaua aaaccacauc aaggacaaca uauaggagaa augucauuuu      960

ugcaacauaa caaaugcgaa ugcaggccaa aaaaagacag agcaagacaa gaaaaaaaaa     1020

guguuagagg aaaaggaaaa ggucaaaaaa ggaaaagaaa aaaaaguaga uauaaaaguu     1080

ggaguguaua uguaggagca agauguuguu uaaugccaug gagucuaccg ggaccacauc     1140

cauguggacc uugcagugag aggagaaaac acuuauuugu ucaagaccca caaacaugua     1200

aauguucuug uaaaaacacu gauagcagau guaaagcucg acaauuggaa uuaaaugaaa     1260

ggacauguag augugauaaa ccaagaagau aaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3701
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt12)

<400>  3701
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuauuaag cuggguacac uggucacuag cauuauuauu auauuuacau cacgccaaau      120

ggucacaagc agcaccaaug gcagaaggag gaggacaaaa ccaccacgaa guaguaaaau      180

uuauggaugu auaccaaaga agcuauugcc auccaauaga aacacuagua gacauauucc      240

aagaauaucc agaugaaaua gaauauauau uuaaaccauc cugcguacca uuaaugagau      300

gcggaggaug cugcaacgac gaaggacuag aaugcguacc aacagaagaa aguaauauaa      360

caaugcaaau aaugagaaua aaaccacacc aaggacaaca cauaggcgaa augaguuucu      420

uacaacauaa caaaugcgaa ugcagaccaa aaaaagacag agcaagacaa gaaaaaaaaa      480

gcguaagagg aaaaggaaaa ggacaaaaaa gaaaaagaaa aaaaagcaga uacaaaagcu      540

ggagcguaua cguaggagca agaugcugcu uaaugccaug gucacuacca ggaccacacc      600

caugcggacc auguucagaa agaagaaaac aucuauuugu acaagaccca caaacaugua      660

aaugcucaug caaaaacacc gacaguagau guaaagcaag acaacuagaa cuaaaugaaa      720

gaaccuguag augugacaaa ccaagaagau aaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  3702
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt12)

<400>  3702
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucac       60

cacuauuaag aagacuacua uuagcagcau uacuacaacu agcaccagca caagcuccag      120

uaagccaacc agacgcaccc ggacaucaaa gaaaaguagu aucauggaua gauguauaca      180

caagagcaac augucaacca agagaaguug uagucccacu aacaguagaa uuaaugggaa      240

caguagcaaa acaauuagua ccaucaugcg uaaccguaca aagaugcgga ggauguugcc      300

cagacgaugg cuuagaaugc guaccaacug gacaacauca aguaagaaug caaauacuaa      360

ugauaagaua cccaucauca caauuaggag aaaugucauu agaagaacau ucacaaugcg      420

aaugcagacc aaaaaaaaaa gacucagcag uaaaaccaga cagagcagca acaccacauc      480

auagaccaca accaagauca guaccaggau gggacucagc accaggagca ccaucuccag      540

cagacauaac acauccaaca ccagcaccag gaccaucagc acaugcagca cccucaacaa      600

caagugcacu aacaccagga ccagcagcag cagcagcuga cgcagcagca ucaucagucg      660

caaaaggagg agccuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  3703
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt12)

<400>  3703
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

uauuaggauu cuuuagcgua gcgugcaguu uauuggcagc agcacuauua ccagguccac      120

gugaagcacc agccgcagcc gcagcuuucg aaucaggauu agacuuaagc gacgcugaac      180

ccgacgcagg cgaagcaaca gcauacgcuu caaaagaucu agaagaacaa cuaagaucug      240

uaucuucagu agacgaauua augacaguac uauacccaga auauuggaaa auguauaaau      300

gccaacuaag aaaaggaggu uggcaacaca auagagaaca agcaaacuua aacuccagaa      360

cagaagagac uauaaaauuu gcagcagcac auuacaacac agaaauucua aaaucaauag      420

acaaugaaug gagaaaaacu caauguaugc caagagaagu augcauagac guagguaaag      480

aauucggugu agccaccaac acauuuuuua aaccaccaug cguaucagua uauagaugcg      540

gaggcuguug caauucagaa ggauuacaau guaugaauac cucuacaagc uaccuaucaa      600

aaacacuauu cgaaauaacu guaccauuau cacaaggacc aaaaccagua acaauaucau      660

uugcaaacca cacaucaugu cgaugcaugu caaaauuaga cguauaccga caaguacaca      720

guauaauaag aagaucacua cccgcaacac uaccacaaug ccaagcagca aauaaaacau      780

gcccaacuaa cuacaugugg aauaaucaua uuuguagaug ccuagcacaa gaagauuuca      840

uguucucaag ugaugcaggu gacgacucua cugacggauu ucaugacaua uguggaccaa      900

auaaagaacu agacgaagaa acaugucaau gcguaugcag agcaggacuu cgaccagcau      960

ccuguggucc acauaaagaa cuagauagaa auucaugcca auguguuugu aaaaauaaau     1020

uauuccccag ccaaugcgga gcaaauagag aauuugauga aaauacaugc caauguguau     1080

guaaaagaac cugcccaaga aaucaaccac uaaacccagg aaaaugcgcc ugcgaaugca     1140

cagaaagucc acaaaaaugu cuauuaaaag guaaaaaauu ccaucaccaa acauguucau     1200

gcuacagaag accaugcaca aacagacaaa aagcauguga accuggauuu ucauauucag     1260

aagaaguuug uagauguguu ccaucauacu ggaaacgacc acaaaugagc uaaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  3704
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt12)

<400>  3704
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguaca       60

gagaaugggu aguaguaaac guauucauga ugcuauaugu acaacuugua caaggaagcu      120

caaaugaaca cggaccagua aaaagaucau cacaguccac acuagaaaga ucagaacaac      180

aaauaagagc agcauccucu cuagaagaau uacuaagaau cacacauucc gaagacugga      240

aauuauggcg augucgacua cgcuuaaaaa gcuuuacuag uauggacuca cgcucagcau      300

cacauagaag uacaagauuu gcagcaacau ucuacgacau agaaacacua aaaguaauag      360

augaagaaug gcaaagaaca caaugcucac caagagaaac augcgucgaa guagcaucug      420

aacucggaaa auccaccaau acauucuuca aaccaccaug cguuaacgua uuuagaugcg      480

gaggauguug caacgaagaa ucacuaauau gcaugaauac auccacauca uacauaucaa      540

aacaacuauu cgaaauaucc guaccauuaa caucaguacc agaacuagua ccaguaaaag      600

uagcaaauca cacaggaugc aaaugccuac caacagcacc aagacacccu uacagcauaa      660

uaagaagauc aauacaaaua cccgaagaag acagaugcuc ccacagcaaa aaauuaugcc      720

caaucgacau gcuaugggac ucaaacaaau gcaaaugcgu acuacaagaa gaaaacccac      780

uagcagguac agaagaccac ucacaccuac aagaaccagc auuaugcggu ccucacauga      840

uguucgacga agauagaugc gaaugcguau gcaaaacacc auguccaaaa gacuuaauac      900

aacacccaaa aaauugcucc uguuuugaau guaaagaauc acuagaaaca ugcugccaaa      960

aacacaaauu auuucauccc gauacaugcu caugcgaaga cagaugccca uuccacacaa     1020

gaccaugcgc aaguggaaaa acagccugcg ccaagcacug ccgauuccca aaagaaaaaa     1080

gagcagcuca aggaccacac ucacgaaaaa auccauaagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  3705
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt13)

<400>  3705
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

cagacgaaac agguuucgaa cacuccggau uauggguauc aguauuagca ggauuacuau      120

uaggagcaug ccaagcacau ccaauaccag acucaucacc acuucuacaa uucggaggac      180

aaguaagaca aagauacuua uacacagaug acgcccaaca aacagaagca cacuuagaaa      240

uaagagaaga cggcacaguc ggaggagcag cagaccaauc accagaaucu uuauuacaau      300

uaaaagcauu aaaaccagga guaauacaaa uauuaggagu aaaaacauca agauuucuau      360

gccaaagacc agacggagca uuauacggau cauuacauuu cgacccagaa gcauguucau      420

ucagagaauu auuacuagaa gaugguuaua auguauauca aucugaagca cacggauuac      480

cacuacaucu accaggaaau aaaucaccac auagagaccc agcaccaaga ggaccagcaa      540

gauucuuacc auuacccgga uuaccuccag cacuaccuga accaccagga auacuagcac      600

cacaaccacc agauguagga ucauccgacc cauuaucaau gguaggacca ucacaaggaa      660

gaaguccauc auacgcauca uaaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  3706
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt13) R4749

<400>  3706
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

cauucccucc acuauuauua uuacuauuuu ggggaguagu aucacacagu uucccugcaa      120

ccuuagaaac acaagaacaa gacguagacc uaguucaaaa auacuuggaa aaauacuaca      180

accuuaaaaa ugacggaaga caaguagaaa aacgaagaaa uucaggacca gucguagaaa      240

aacuaaaaca aaugcaagaa uuuuucggac uaaaaguuac aggaaaacca gaugcagaaa      300

cacuaaaagu aaugaaacaa ccuagaugug gaguacccga cguagcccaa uuuguauuaa      360

cagaaggcaa cccaagaugg gaacaaaccc acuuaaccua cagaauagaa aauuacacac      420

cagaucuacc uagagccgac guagaucaug cgauagaaaa agcauuucaa uuauggagua      480

auguaacucc acuaacauuu acaaaagucu cagaaggaca agcggacaua augauauccu      540

ucguaagagg agaucacaga gacaauaguc cauucgacgg accaggcgga aaccuagcac      600

acgcuuucca accaggaccc ggcauaggag gagaugcaca cuucgacgaa gacgaaagau      660

ggacaaacaa cuucagagaa uauaaccucc acagaguagc ugcacaugaa cuaggacauu      720

cauuaggacu uagccacagc acagacauag gagcacuaau guacccuuca uauacauuuu      780

caggagacgu acaauuagca caagacgaua uagacggaau acaagcaaua uauggaagau      840

cacaaaaucc uguacaaccg aucggaccuc agacaccaaa agcaugcgau agcaaacuua      900

ccuucgacgc uauaacaaca auuagaggcg aaguaauguu cuucaaagac cgauuuuaca      960

ugagaacaaa uccauucuau cccgaaguag aauuaaacuu uauauccgua uuuuggccac     1020

aacucccuaa cggauuagaa gccgcauacg aauuugcaga uagagacgaa guaagauuuu     1080

ucaaaggaaa caaauacugg gcuguacaag gacaaaacgu acuacacgga uauccaaaag     1140

acauauacuc aucauucggc uuuccccgaa caguaaaaca uauagaugca gcauuaucag     1200

aagaaaacac aggaaaaaca uauuucuuug uagccaacaa auacuggaga uaugaugaau     1260

acaaaagauc aauggaccca gguuacccaa aaaugauagc acaugauuuu ccaggaauug     1320

gacauaaagu cgacgccguc uucaugaaag acggauucuu cuauuucuuu cauggaacua     1380

gacaauauaa auucgaccca aaaacaaaaa gaauauuaac acuacaaaaa gcaaacucuu     1440

gguucaacug uaggaaaaau uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  3707
<211>  1552
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt13) 
       R4751

<400>  3707
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

cauuuccacc auuacuacuc uuauuauuuu ggggaguagu aucacacuca uucguacuaa      120

cagaaggaaa uccaagaugg gaacaaacac accuuaccua cagaauagaa aauuacacac      180

cagaucuacc aagagcagac guagaccacg caauagaaaa agcauuucaa uuauggucaa      240

acguaacacc auuaacauuc acaaaaguau cagaaggaca agcagacaua augauaucau      300

ucguaagagg agaccacaga gacaauucac cauuugaugg accaggaggu aaucuggcac      360

acgcauucca accaggacca ggaauaggag gagacgcaca cuucgacgaa gacgaaagau      420

ggacaaacaa cuucagagaa uacaaccuac acagaguagc agcccaugaa cuaggacacu      480

cacuaggacu aucacacuca acagacauag gagcccuaau guauccaucc uacacauucu      540

caggagacgu acaacucgcg caagacgaca uugacggaau ccaagcuaua uacggaagau      600

cacaaaaccc aguacaacca auaggccccc aaacaccaaa agcaugugac ucaaaacuaa      660

cauuugaugc aauaacaaca auaagaggcg aaguaauguu cuucaaagac agauucuaca      720

ugcgcacaaa uccauucuac ccagaagucg aauuaaacuu cauaucagua uucuggcccc      780

aauuaccaaa cggauuagaa gccgccuacg aauuugcaga ccgagacgaa guaagauucu      840

ucaaaggaaa caaauauugg gcaguacaag gacaaaacgu auuacacgga uauccaaaag      900

acauauacuc cucauuuggc uuuccaagaa caguaaaaca uaucgacgca gcacucuccg      960

aagaaaacac aggaaaaaca uacuucuuug uagcaaacaa auacuggaga uaugacgaau     1020

auaaaagauc aauggacccg ggauacccaa aaaugauagc acaugacuuc ccaggaauag     1080

gacacaaagu agacgccgua uucaugaaag acggauuuuu cuacuucuuu cacggaacua     1140

gacaauacaa auucgaccca aaaacaaaaa ggauacuaac auuacaaaaa gcaaacucau     1200

gguuuaacug ccgcaaaaac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1260

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1320

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1380

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1500

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1552


<210>  3708
<211>  3739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt13)

<400>  3708
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

aaaauauacu uaaaauacuc auggacucau acaguaaaga aagcaaaauu caaacgguuc      120

gaagaguaac cagugucagc cuauuagcag uauaucuaac uaugaauacu agcagcuuag      180

uacucgcgaa accaauugaa aauacaaaug acacaaguau uaaaaaugua gaaaaauuga      240

gaaaugcacc aaaugaagaa aacucgaaga aaguagaaga uagcaaaaau gauaaaguug      300

agcauguuaa aaacauagaa gaagcaaaag ucgaacaggu ggcuccagaa guaaaaucaa      360

aaagcacacu cagaucagca aguaucgcaa acacgaacag ugagaaauau gauuuugaau      420

accugaaugg ccucucauau acagaauuaa caaacuuaau uaaaaauaua aaauggaauc      480

aaaucaacgg cuuauucaau uacaguaccg gaagucagaa auucuuuggg gacaaaaacc      540

gaguacaagc aauaauuaau gcauuacaag aaucagggcg aacauauaca gccaacgaua      600

ugaaaggaau ugaaacauuc accgagguuu uacgagcugg cuucuauuug ggcuacuaca      660

acgauggacu auccuauuug aacgauagaa acuuucagga uaaauguaua ccagcaauga      720

ucgcaauaca gaagaaccca aacuucaaau uaggaacagc aguacaagau gaaguaauua      780

ccagucuugg uaaauuaauu ggaaacgcaa gcgcgaaugc ugaaguugua aauaacugug      840

ucccagucuu aaaacaauuu agagagaauu uaaaucaaua ugcaccagau uacguuaaag      900

gaacagcggu uaaugaauua auaaaaggaa uagaguucga cuuuagcgga gcagcuuacg      960

aaaaagacgu aaaaacuaug ccuugguacg gaaagauuga uccauucaua aacgaauuaa     1020

aagcauuggg ccucuacgga aauauaacau cagcuacaga augggccagc gaugugggua     1080

uauacuaucu uaguaaauuc ggucuuuaua guacaaacag gaaugauauc guucaaucac     1140

uagaaaaagc aguagauaug uauaaauacg gaaaaauagc auuuguggca auggaaagaa     1200

uaacauggga cuaugaugga auaggaucua acggcaagaa aguagaccau gacaaauuuc     1260

ucgacgaugc cgaaaaacac uacuuaccaa aaacguauac auuugacaau ggaacauuua     1320

ucauaagagc gggugacaaa guaagugaag agaaaauaaa aagacuauac ugggcaucua     1380

gagaaguaaa aucucaauuu cacagggucg ucgggaauga caaagcacua gaaguaggaa     1440

acgccgacga uguccucaca augaaaauau ucaacagccc cgaagaauau aaauucaaua     1500

cuaauauaaa uggaguuagc acagacaaug gcggauuaua uauagaacca cgagggacuu     1560

ucuacacgua ugaaagaaca ccacaacaau caauauucag cuuagaagaa cuguuuagac     1620

augaauauac ucauuacuua caagcucgau auuuagugga uggauuaugg ggacaaggcc     1680

ccuucuacga gaaaaacaga cuaacuuggu ucgacgaagg aacagcagag uucuucgccg     1740

gcucaaccag gacaucagga gugcuuccga gaaaaucaau acuaggcuau cuugcaaaag     1800

auaaaguaga ccacagauac agccucaaga aaacauuaaa uucaggauau gaugauagcg     1860

auuggauguu uuauaauuau ggguuugcug uagcccacua uuuauaugaa aaagauaugc     1920

caacauuuau aaaaaugaau aaagcaauuc uaaauaccga cguuaaaagc uaugaugaaa     1980

uaauaaagaa auuaucagac gacgcgaaca aaaacacaga auaucaaaau cacauacaag     2040

aauuagccga caaauaucaa ggagcaggca uacccuuagu gucagacgac uauuuaaaag     2100

aucauggaua uaagaaagcg uccgaaguau auucugaaau aucuaaagcg gcaagccuaa     2160

caaauacauc cguaacagcg gaaaaaucac aauacuuuaa uacauuuaca cuaagaggaa     2220

cauauacagg agaaacaagu aaaggcgaau uuaaagacug ggacgaaaug agcaagaaac     2280

uggacggaac acuagaaagc cuagcuaaaa acucauggag cggauauaaa acauuaacgg     2340

cauauuuuac caauuaccga guaacguccg acaacaaagu acaauaugac guuguauuuc     2400

acggcguuuu aacagauaac gcagauauaa guaauaacaa agcaccaaua gcaaaaguua     2460

caggcccauc gacaggugcc guagguagaa acauugaauu uucuggaaaa gauucaaaag     2520

augaagaugg aaaaaucgua ucauacgacu gggacuuugg agacggagca acaucaagag     2580

ggaaaaauuc aguccaugca uacaagaaag cuggaacaua uaacguaaca uuaaaaguua     2640

ccgaugauaa aggugcgaca gcaacugaau cuuuuacaau cgaaaucaaa aacgaagaua     2700

caacaacacc aauaacgaaa gaaauggaac ccaaugacga uauaaaagaa gcuaauggac     2760

caauagucga aggaguaacc gucaaaggug accuaaacgg cuccgacgac gcugauacau     2820

ucuauuuuga uguuaaagaa gauggagaug ugacaauaga acuaccauau ucaggaucua     2880

guaacuuuac cuggcuggua uauaaagaag gcgaugauca aaaucauauc gcuaguggua     2940

uagacaaaaa uaacagcaaa guuggaacau uuaaaagcac aaaagguaga cauuacguau     3000

ucauuuacaa acacgauuca gcaucaaaua ucucauacuc uuuaaauaua aaaggcuuag     3060

guaaugaaaa acugaaagag aaagaaaaua augauucguc agacaaagcu acagugauac     3120

caaauuucaa uacaacuaug caaggaucac ugcuaggaga ugacagccgu gauuauuaca     3180

gcuucgaagu aaaagaagaa ggagagguaa acaucgaauu agauaagaaa gaugaauuug     3240

gaguaacaug gacauuacau ccagaaucca acauaaacga cagaauaaca uacggacaag     3300

uugaugguaa caaaguaagu aauaaaguaa aauugaggcc uggaaaauac uaccuguuag     3360

uauauaaaua caguggguca ggaaacuacg aacuacgagu uaacaaauaa ggacuagugc     3420

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     3480

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     3540

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     3600

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     3720

uuucagagcc accagaauu                                                  3739


<210>  3709
<211>  3463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt13)

<400>  3709
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

ggguaacuuu uauaagucuu cuauuucuau uuucaucggc auauaguaua gcaaacacaa      120

acucagaaaa auaugacuuu gaauaucuaa auggauuauc auauacagaa uuaacaaacc      180

ugaucaaaaa cauaaaaugg aaucaaauaa acggauuauu uaacuauagc acgggaucac      240

agaaauuuuu cggcgauaaa aauagaguac aagcaauuau aaaugcucuc caagaaucug      300

gcagaacgua uacagcaaac gauaugaaag gaaucgaaac uuuuacagaa guccugagag      360

cagguuuuua cuuagguuau uacaacgacg ggcuaagcua ucuaaaugau agaaacuucc      420

aagacaaaug uauaccagca augauugcaa uacagaaaaa ccccaauuuu aaauuaggaa      480

cagcaguuca agacgaaguu auaacaucuc uuggcaaacu uauagggaac gcaagcgcaa      540

acgcagaagu aguaaacaac uguguaccgg uauuaaaaca auucagagaa aauuuaaauc      600

aauacgcacc agacuaugua aaaggaacag caguaaacga acuaauaaaa ggaauagaau      660

uugauuucag cggagccgca uaugaaaagg augucaaaac uaugccgugg uacggaaaaa      720

uagacccauu uauaaaugaa cuuaaagcac uagguuuaua cggaaacauc acaagcgcaa      780

cugaaugggc aucagauguu ggaauuuauu accuaucuaa auuuggacua uacucaacca      840

acaggaacga uauagugcaa ucucuggaaa aagcuguaga cauguauaaa uauggaaaaa      900

uagcuuucgu cgcaauggaa agaauaacuu gggauuauga ugguauugga ucaaacggca      960

aaaagguaga ucacgauaaa uucuuagaug acgcagaaaa gcacuacuua ccaaaaacgu     1020

auacauucga caacgggacu uuuauaauca gagcaggcga uaaaguaucc gaagagaaaa     1080

uaaaaagauu auacugggcu ucaagggaag uaaaaucuca auuccaccga guaguaggaa     1140

augauaaagc auuagaagug gguaacgcug augauguauu aacaaugaaa auauucaaca     1200

gcccugaaga auacaaguuc aauacaaaua uaaacggagu cucuaccgau aacggaggcu     1260

uauacauuga accaagagga acauuuuaca cauaugaaag aacuccacaa caaagcauau     1320

ucagccuuga ggaacuauuc cgacacgaau auacacauua cuuacaagcc agguaucuug     1380

uagauggacu uuggggacag ggaccuuucu augaaaagaa uagacuaacc ugguucgacg     1440

aaggaacagc agaguucuuu gcagguucaa caagaacauc uggaguauua ccacgaaaau     1500

caauucucgg uuauuuagca aaagauaaag uagaucauag auauucacua aagaaaaccu     1560

ugaacucagg auacgacgac agugacugga uguucuacaa uuacggauuu gcaguagcac     1620

acuauuuaua ugaaaaagau augccuacau ucauuaaaau gaacaaagca auacuaaaua     1680

ccgaugugaa aagcuaugac gaaauaauaa agaaacuuuc agacgaugcg aacaaaaaua     1740

cagaauacca aaaccauauu caagaacucg ccgacaaaua ccaaggugca ggcauuccuc     1800

uaguaaguga cgacuauuua aaagaccaug gauacaagaa agcaucagaa gucuauucag     1860

aaaucagcaa agccgcaucc uuaacuaaua caagcgucac agcagagaaa ucacaauacu     1920

uuaauacauu cacgcuucga ggaacuuaua caggugaaac gucaaaagga gaguuuaaag     1980

auugggauga aaugucaaag aaauuagaug gaacacuaga aucguuagcu aaaaacucau     2040

ggucuggaua uaaaacacua accgcauacu uuacuaacua cagaguuacc agugauaaca     2100

aaguacaaua cgauguagua uuucauggag uacuaacaga caaugcagac auuagcaaua     2160

acaaagcacc aauagcaaaa guuaccggcc ccucaacagg ggcaguaggu agaaauauug     2220

aguucucugg aaaagauagc aaagaugaag auggaaaaau aguuucauau gauugggacu     2280

uuggugaugg agcaacuagc aggggcaaaa acucaguuca cgcauacaag aaagcaggaa     2340

cauauaacgu aaccuuaaaa guaaccgaug auaaaggagc aaccgccacc gaaaguuuua     2400

cuauagaaau caaaaacgaa gacacaacga caccaauaac aaaagaaaug gaaccaaaug     2460

acgacauaaa agaagcaaac ggaccaauag uagaaggagu aacaguaaaa ggagaccuaa     2520

auggcucgga cgaugcagau acauuuuacu uugaugucaa agaggauggu gacguaacca     2580

uagaacuacc cuauagcgga ucaaguaauu ucacuuggcu aguuuacaaa gaaggagaug     2640

accaaaacca uauugcauca ggaauugaua aaaacaacuc aaaaguaggc acauucaaau     2700

caacaaaagg acgacauuac guuuucauau auaaacacga cagcgcuuca aacauaucau     2760

auucucucaa cauaaaaggu uuaggcaaug aaaaauuaaa agaaaaagaa aauaacgacu     2820

caucagauaa agcaaccgua aucccaaauu ucaauacaac gaugcaagga ucgcuccucg     2880

gagaugacag ucgugauuac uacucauuug aaguaaaaga agaaggagaa guuaauauag     2940

aacuagauaa gaaagacgag uucggaguaa cauggacauu acacccagag aguaauauca     3000

acgauagaau uacauauggc caaguugacg gaaauaaagu uaguaauaaa guaaaacuua     3060

ggccaggaaa auauuaccug cucgucuaca aauacucagg uagcgguaac uaugaacuaa     3120

gaguaaacaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3180

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3240

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3300

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3420

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3463


<210>  3710
<211>  3811
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt13)

<400>  3710
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

ggguaacauu cauuagccuc uuauuucuau uuucaucagc auacaguaug aagaaaaaua      120

uacuaaaaau auugauggac uccuauagua aagagagcaa aauacaaaca guaaggcgag      180

uaaccagcgu gaguuuacuu gcuguauauc uaacaaugaa cacaaguagc cuaguuuuag      240

caaaaccaau agaaaauacg aaugauaccu ccaucaaaaa cguagaaaaa cuaagaaaug      300

caccaaacga agaaaauuca aagaaaguag aagauaguaa aaacgacaaa guagaacaug      360

ugaaaaacau agaagaagcc aaaguagaac aaguagcacc agaagucaaa ucuaaaucca      420

cuuuaagaag ugcgucaagg agaagaagaa aaagaauagc aaacacaaau agugaaaaau      480

acgauuucga auaccuaaac ggacuauccu auacugaacu aacaaaucua auuaaaaaca      540

uaaaauggaa ucaaauaaac gguuuauuua acuauuccac aggcucacaa aaauuuuucg      600

gagauaaaaa ucgcguucaa gcaauaauaa augcccuaca agaaagcggg agaaccuaca      660

ccgcaaauga uaugaaagga auagaaacau ucacagaagu acuuagagcc gguuucuauc      720

uagguuacua uaacgacgga uuaaguuauc uaaaugauag gaacuuccaa gauaaaugca      780

uaccagcaau gaucgcaaua cagaaaaauc caaauuucaa auugggaaca gcaguccaag      840

acgaagugau aacaucacua ggaaaacuaa uaggcaacgc aagugcaaac gccgaaguag      900

uaaacaacug uguuccagua cuaaaacaau ucagagaaaa ccuaaaccaa uacgcaccug      960

auuauguuaa agguacagcc gucaacgaac ucauaaaagg uauagaguuc gacuucucag     1020

gagcagcgua cgaaaaagau guaaaaacaa ugccauggua uggaaaaauu gauccauuua     1080

uuaaugaauu aaaggcauua ggauuguacg gaaacauaac cucggcuaca gaaugggcau     1140

cagauguagg aauauacuac cuuucaaaau uuggucuaua uagcacaaac cggaacgaua     1200

uaguacaauc auuagaaaaa gccguagaca uguauaaaua uggaaaaaua gcauuugucg     1260

caauggaaag aauaaccugg gacuacgacg gaauaggguc uaacgggaag aaaguagacc     1320

augauaaauu ucucgaugau gccgaaaaac auuaucuacc uaaaacuuac acuuucgaca     1380

auggcacauu cauaaucaga gcuggcgaca aaguauccga agagaaaaua aaaagauuau     1440

auugggcauc uagagaggua aaaagucagu uucacagagu cguaggaaau gauaaagcuc     1500

uugagguagg aaacgcagau gacguguuaa caaugaaaau auuuaauuca ccggaagaau     1560

acaaguucaa uacaaacauu aauggcguau ccacagacaa uggaggacua uauaucgaac     1620

cacgaggaac auucuauaca uaugaaagaa ccccacaaca gaguauuuuc agucuagaag     1680

aauuauuuag gcacgaauac acccauuauu uacaagcacg uuaucuagua gacggacuau     1740

ggggucaggg acccuucuac gaaaagaacc gcuuaacaug guucgaugaa gguacugcgg     1800

aauuuuucgc uggaucaaca cgaaccagug gaguacuccc aagaaaauca auuuuagguu     1860

accuugcaaa agauaaaguc gaucacagau acucacucaa aaagacacua aauucaggau     1920

augaugacuc agacuggaug uuuuauaauu auggauucgc agucgcacac uaccucuacg     1980

aaaaagauau gccaacguuc auuaagauga auaaggcaau acuaaauaca gauguaaaau     2040

cauacgacga aaucauaaag aaacuauccg acgacgcaaa uaaaaauaca gaauaccaaa     2100

accauauaca agaacuagca gacaaauauc agggagcagg caucccacuu guaagcgacg     2160

acuacuugaa agaccacgga uacaagaaag cauccgaagu cuacucagaa auauccaaag     2220

cagccucauu aacaaauacg uccguaacug cugagaaaag ucaauauuuc aacacauuca     2280

cacuacgugg aacauacacc ggcgaaacga guaaaggaga guucaaagau ugggacgaaa     2340

ugucaaagaa auuagacggu acacuagaau cauuagccaa aaauucaugg agcggauaca     2400

aaacucuuac ggcauacuuu acaaacuaua ggguuacaag ugauaacaaa guacaauaug     2460

acguaguauu ucauggaguc cucacagaca augcugauau cagcaacaac aaagcuccua     2520

ucgcuaaagu aacugggccc aguacgggag caguaggcag aaacauugag uucucaggaa     2580

aagacucaaa agacgaagau ggcaaaauag uauccuauga uugggacuuu ggagauggag     2640

caacaucaag aggcaaaaac ucaguccacg cauacaagaa agcaggaaca uauaauguaa     2700

cacuuaaagu aacagacgau aaaggcgcaa cagcaacaga aucauucaca auagaaauua     2760

aaaacgaaga uacaacaaca ccaauaacaa aagaaaugga accaaacgau gauauaaaag     2820

aggcaaacgg uccaauagug gaaggaguaa caguaaaagg cgacuugaau gggagcgacg     2880

acgccgacac auuuuauuuc gacguuaaag aggacggcga cguaacaaua gaauuaccau     2940

acaguggauc aagcaacuuu acguggcuag uuuauaaaga aggagacgac caaaaccaua     3000

uagcaagugg uauagacaaa aacaauagua aaguagguac auuuaaaagu accaaaggca     3060

gacauuacgu auuuauauac aaacacgauu cagcaucaaa cauaucauau ucucuaaaua     3120

uaaaaggauu agggaaugaa aaacuuaaag aaaaagagaa uaaugacagc agcgacaaag     3180

caacugucau acccaacuuu aacacaacaa ugcaagguuc acuauuagga gacgacaguc     3240

gagauuauua uagcuucgaa guaaaagagg aaggagaagu caauauagaa uuagauaaga     3300

aagacgaauu uggaguaaca uggacacuuc auccugaaag uaauauaaac gauagaauaa     3360

cauacggaca aguagacgga aacaaagucu caaauaaagu aaaacuuaga ccagggaaau     3420

auuaucuacu uguauauaaa uacaguggau cagguaacua ugaacuaaga gucaauaaau     3480

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3540

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3600

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3660

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc     3780

cccaaaggcu cuuuucagag ccaccagaau u                                    3811


<210>  3711
<211>  3487
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt13)

<400>  3711
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

ucuugaaaau aauccucaac agaggaaaaa ccaugaaacg aaaaugucug ucaaaaagau      120

uaaugcuagc uauaacaaug gccaccauau ucacagucaa cucaacacua ccaaucuaug      180

cagcaguaga uaaaaauaau gcuacagcug caguacaaaa cgaaucaaaa cguuauacag      240

uuucguacuu aaaaacauua aauuauuaug accucgucga ucuauuggua aaaacagaaa      300

ucgaaaauuu accagauuua uuccaauaca gcucagaugc uaaagaguuc uaugguaaca      360

aaacaagaau gagcuucauu auggacgaaa uagguagaag ggcuccacaa uauacagaaa      420

uagaccauaa aggaauacca acccuaguag aaguagucag agccggauuu uaucuuggau      480

uccacaacaa agaauuaaau gaaaucaaca aaagaucauu caaagaacga guaaucccaa      540

gcauauuagc aauacaaaag aauccaaauu ucaaauuagg aacagaaguu caggacaaaa      600

uaguuagcgc aacaggacuu cuagccggaa augaaacagc accuccugaa guaguaaaua      660

acuuuacacc aauauugcag gauugcauaa agaacauaga uagauacgcg uuagaugacc      720

uaaaaucuaa agccuuauuc aaugugcuug cagccccaac auacgacauc acugaauauc      780

uccgagccac aaaagaaaaa ccagaaaaca caccauggua cgggaaaaua gacggauuca      840

uaaacgaacu caagaaacua gcauuauaug guaaaauaaa cgacaacaac ucauggauca      900

uagacaaugg uauauaccau auagccccau uaggaaaacu ucacagcaau aauaaaauag      960

gaauagagac auuaacagaa guaaugaaag uauacccuua uuuaaguaug caacauuuac     1020

aaucagcaga ccaaaucaaa agacauuacg acaguaaaga cgcggaagga aacaaaauuc     1080

cauuagacaa auuuaaaaag gaaggaaaag aaaaauauug uccaaaaacc uacacauuug     1140

acgauggaaa agucauuaua aaagccggag cacguguaga ggaagaaaaa gugaaaagac     1200

uuuacugggc auccaaagaa guaaauucac aauucuuucg aguuuacgga auugacaaac     1260

cccuggaaga aggaaaccca gacgacauuu uaacgauggu aauauacaac aguccugaag     1320

aauacaaacu aaacagugua cuauauggcu acgauacgaa caacggagga auguacaucg     1380

aaccagaagg aacauucuuu acguacgaaa gagaagcaca ggaaucaacu uauacacuag     1440

aggaacuauu ucgacacgaa uacacacacu aucuccaagg uagauaugca guuccgggac     1500

aauggggaag aacuaaguua uacgauaaug acagacuaac augguaugaa gaaggagggg     1560

ccgaguuauu cgcgggcagu accagaacaa gugggauauu acccagaaaa agcauuguau     1620

ccaacauaca caacaccacg aggaauaacc gauauaaacu uucagauaca guccauucaa     1680

aauauggagc aucguuugag uucuacaauu augcaugcau guuuauggau uauauguaua     1740

auaaagacau gggaauacuc aacaaauuaa augaccuagc aaagaacaau gacguggacg     1800

gauacgacaa cuacauaaga gaccuaucaa gcaacuacgc acuaaaugac aaauaucaag     1860

accacaugca agaaagaaua gauaacuaug aaaaucucac aguaccuuuc guugcagaug     1920

acuaccuagu ccgucaugca uacaaaaauc cgaacgaaau auauucagaa auuucagaag     1980

uugcuaaacu uaaagaugcc aaaucagaag uaaagaaaag ucaauacuuc aguacuuuua     2040

cacuacgcgg aagcuacacu ggaggagcuu caaaaggaaa auuagaagac caaaaagcca     2100

ugaacaaauu cauagacgau agccucaaga aauuagauac guauaguugg ucuggauaua     2160

aaacacuaac agcguauuuu acaaauuaua aagucgauag uagcaacaga guaacauacg     2220

auguaguauu ucauggauau uuaccaaaug aaggagauuc caaaaauuca cucccguaug     2280

gaaaaauaaa cgguacauau aaagggacag aaaaagagaa aauaaaauuc agcucagaag     2340

gaaguuuuga cccggacggu aaaauaguaa guuacgaaug ggacuucggu gacggcaaua     2400

aaucaaacga agaaaaucca gaacacucuu augauaaagu aggaaccuac acagugaaau     2460

uaaaaguaac agaugauaaa ggugaaucau ccgucaguac gacaacagca gaaauaaaag     2520

aucugucaga aaacaagcuc ccgguuauau auaugcaugu accaaaaagc ggcgcccuaa     2580

aucaaaaagu agucuuuuac ggaaaaggaa cguaugaccc agacggaagu auagcaggau     2640

accaauggga uuuuggggau gguagugacu uuagcagcga acaaaaccca ucacaugucu     2700

acacuaagaa aggcgaguac acaguuacac ucagaguaau ggacucaagu ggacaaaugu     2760

cagagaaaac aaugaaaaua aaaauaacag auccaguaua uccaauugga acugaaaaag     2820

aaccaaacaa uucuaaagaa acagccucag gucccauugu cccuggcaua ccuguaagug     2880

gaacaauaga aaacaccagu gaccaagacu auuucuauuu ugacguuaua acacccggcg     2940

aaguaaaaau agacaucaac aaacuuggau acggaggagc uacauggguu guauaugaug     3000

aaaacaauaa ugcaguaagu uaugcaacug augauggaca aaaccuaagc ggaaaauuua     3060

aagcagauaa acccggacga uauuauauac acuuauauau guucaacgga aguuauaugc     3120

cauaucgaau aaauauagaa ggaagcguag gaagauaagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     3480

cagaauu                                                               3487


<210>  3712
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt13)

<400>  3712
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

gaaaauguuu aagcaaaaga uuaaugcuag ccauuacaau ggcaacaauu uucacaguaa      120

auaguacauu accaauuuac gcagcugucg acaaaaacaa cgcaacugca gcaguacaga      180

acgaaucaaa acgguauaca gugagcuacc ucaaaacacu aaauuauuau gaccuaguag      240

aucuacuugu aaaaacagaa auugaaaauc uaccagaccu auuccaauac uccucagaug      300

caaaggaauu uuauggaaac aaaacgcgca ugaguuucau uauggacgaa auaggaagga      360

gggccccaca guacacagaa auagaucaua aaggcauacc aacgcuagua gaagucguaa      420

gagcaggauu uuaccuaggu uuucacaaca aagaacucaa cgaaauaaac aagcgcaguu      480

uuaaagaaag agucauucca ucaauauuag cgauccagaa aaacccuaac uucaaacuag      540

gaacagaagu acaagacaaa auuguaucag cgacaggacu acuagcagga aaugagacag      600

caccaccaga aguaguaaau aauuucacac caauauuaca agacugcauc aaaaauauag      660

accgauacgc auuggaugac uugaaaagca aagcauuauu uaauguacuu gcggcaccaa      720

cauaugacau aacagaauac cuaagagcua caaaggaaaa accagaaaac acaccauggu      780

auggaaaaau agacggauuu auaaaugaac ugaaaaaguu agcacuauac gguaaaauca      840

augacaacaa cagcuggaua auagacaaug ggaucuacca uauagcccca uuagguaaac      900

uacauucaaa caacaaaaua ggaaucgaaa cccuaacaga aguaaugaaa guauauccau      960

accuaagcau gcaacacuug caaagcgcag accaaauaaa aaggcacuau gacagcaaag     1020

augcagaagg aaacaaaaua ccacucgaca aguucaagaa agaagguaaa gaaaaauauu     1080

gucccaaaac guauacguuc gaugacggaa aaguaaucau aaaagcagga gccagaguag     1140

aagaagaaaa aguaaaaaga cuuuauuggg cuucgaaaga agucaacagc caauucuuca     1200

gaguauaugg uaucgacaaa ccucuagaag aaggaaaucc agaugacauu cuaacaaugg     1260

uaauauacaa cucaccggag gaauacaaau uaaacagugu ccuguacgga uacgauacaa     1320

acaacggugg cauguauaua gaaccagaag guacauucuu cacuuaugaa agagaagcuc     1380

aagaaagcac cuacacauua gaggaauuau uuagacauga auauacucac uauuuacaag     1440

gccgauaugc aguaccaggc caaugggggc guacaaaauu auacgauaac gauagauuaa     1500

caugguauga agaaggugga gccgaacuau ucgcagguuc caccaggacu ucaggaauac     1560

uaccaaggaa aucaauugua aguaauauac acaauaccac acguaacaac agauacaaau     1620

uauccgacac aguacacuca aaauacggag caucauucga guucuacaau uacgcaugua     1680

uguuuaugga uuauauguau aauaaagaua ugggaauccu aaacaaacua aaugacuuag     1740

cuaaaaauaa ugacguugac ggauacgaca auuacauaag ggacuuaagu agcaacuacg     1800

cauuaaacga caaauaccaa gaccauaugc aagaaagaau agauaacuau gaaaaucuaa     1860

cgguaccauu uguugcagac gauuauuuag ucagacaugc auacaaaaac ccuaaugaaa     1920

uauacaguga aauaucagaa guggcaaaac uaaaagacgc uaaaucugaa guaaagaaaa     1980

gccaauacuu uaguacauuc acacuucgag gcucauacac aggaggagca agcaagggua     2040

aacucgaaga ccaaaaagca augaacaaau uuauagauga uucacuaaag aaauuagaca     2100

cauauaguug gagcggcuau aaaacacuaa ccgcauacuu uacuaacuau aaaguagacu     2160

caucaaaccg cguaacauac gacguaguau uucacggaua ccuccccaau gaaggugaca     2220

gcaaaaacuc acuacccuau gggaaaauaa augggacaua caaagguacc gaaaaggaga     2280

aaauaaaauu uucuucugaa ggcagcuucg acccagacgg aaaaauaguc uccuacgaau     2340

gggacuucgg ugauggaaac aaaagcaaug aagaaaaucc agaacacagu uacgacaaag     2400

uagggacuua cacuguaaaa cugaaaguua cagaugacaa gggcgaaagc ucuguaagua     2460

caaccacugc cgaaauaaaa gaccuaucag aaaacaaacu uccaguaaua uauaugcacg     2520

uuccuaaauc uggagcuuug aaccaaaaag uaguuuucua cggaaaaggc acguaugacc     2580

cggauggauc aaucgcaggc uaucaauggg acuuuggcga uggaagugac uuuuccagcg     2640

aacaaaaccc uagccacguc uauacuaaga aaggagaaua uaccgugaca uuacgaguaa     2700

uggauucauc aggacaaaug ucagagaaaa ccaugaaaau aaaaaucacu gacccaguau     2760

auccaauagg aacagaaaaa gaaccaaaca acaguaaaga aacagccuca gguccaauag     2820

uaccuggaau accagucuca ggcacaauag aaaacacauc agaccaagac uacuucuauu     2880

uugauguuau aacaccaggu gaagucaaaa uagauauaaa uaaauuagga uaugguggug     2940

caacaugggu cguauacgau gaaaacaaua acgccguuag uuacgcaaca gacgaugguc     3000

aaaaccuauc ugggaaauuc aaagcagaua aaccuggaag auacuauaua caucuauaua     3060

uguuuaacgg cagcuacaug ccauauagaa uaaauauaga agggucagua ggaagauaag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  3713
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt13)

<400>  3713
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

ggguaacuuu uauaucauua uuauuccuau ucaguucagc auauagugua caaaaugaau      120

caaaaaggua cacaguaucc uaucuaaaaa cguuaaauua uuacgauuua guagaucucc      180

uagucaaaac ugaaauagaa aacuuaccag accuauucca auauucgucc gaugcaaaag      240

aauuuuaugg aaauaaaacc cgaaugucau ucaucaugga cgaaauugga cgaagggcac      300

cgcaauacac agaaauagau cacaaaggua uuccaacccu cguagaaguc guaagagcug      360

gcuucuaccu aggauuucau aauaaagaau uaaaugaaau aaacaaaagg ucauucaaag      420

aaagaguaau acccuccaua uuagcaauac aaaaaaaucc uaacuuuaaa cuuggaacag      480

aaguucaaga caaaaucguu ucagcgaccg guuuacuggc aggcaacgaa acagcaccuc      540

ccgaagucgu aaacaacuuc acaccaauuu uacaagauug uauaaaaaau auugaucgau      600

acgcuuuaga cgaccuuaaa agcaaagcgc uauucaacgu acucgcagca ccuacauacg      660

auaucaccga auaccuucga gcuacaaaag aaaaaccaga aaauacuccu ugguauggca      720

aaauagacgg auucauaaac gaauuaaaaa aauuagcuuu auauggaaaa auuaaugaua      780

auaacucaug gauaauagac aauggaauau aucacauugc accauuagga aaauuacauu      840

cuaauaauaa aauaggaaua gaaacauuga cagaaguaau gaaaguguac cccuaccuaa      900

gcaugcaaca uuuacaguca gcugaucaaa uuaaacgaca cuacgauuca aaagacgcag      960

aaggcaauaa aaucccacuu gacaaauuca aaaaagaagg aaaagaaaaa uacuguccaa     1020

aaacauauac auuugacgac ggaaaaguaa uaauaaaagc uggugcaaga guagaagaag     1080

aaaaagucaa aagacuauau ugggcaagca aagaaguaaa uucacaauuc uuucgaguau     1140

auggaauuga caaaccccua gaagagggaa acccagacga uauacuaaca auggugauau     1200

acaacucacc agaagaauau aaacuaaaca guguacuaua cggauacgau acaaacaaug     1260

gcgggaugua cauagaacca gaagguacau ucuucacgua ugaaagggaa gcacaagaau     1320

ccaccuacac acucgaagaa cuauucagac augaauacac ucauuaucua caaggcagau     1380

augccguacc gggacaaugg ggaagaacaa aauuauauga caacgacaga uuaacauggu     1440

augaagaagg aggagcagaa cuauuugcug gcaguaccag aacaaguggg auccuuccca     1500

gaaaaucaau ugugaguaac auacacaaca caacgagaaa uaauagauau aaacuaagcg     1560

auaccguaca uaguaaauau ggagccucgu ucgaauuuua uaauuaugcc uguauguuca     1620

uggauuacau guauaacaaa gauaugggua uauuaaauaa auuaaacgac cucgcuaaaa     1680

auaaugaugu agacggauac gacaacuaca uaagagauuu auccagcaac uaugcauuaa     1740

augacaaaua ucaagaccac augcaagaaa gaaucgacaa cuaugaaaau cuuacuguac     1800

cauucguagc agacgauuac cuaguuagac acgccuauaa aaaucccaac gaaauauaua     1860

gcgaaauauc ugaaguagca aagcuaaaag acgcaaaaag cgaagugaaa aaaucacaau     1920

acuuuucaac uuucacauug agaggcucau acacaggagg ugcaagcaaa ggaaaauuag     1980

aagaucaaaa agcaaugaau aaauuuauag acgacagucu aaaaaaauua gauacauacu     2040

cauggucagg uuacaaaaca cuaacggcau acuucacaaa cuauaaagua gauuccucaa     2100

auagaguaac auacgauguc guuuuucaug gauaucuacc uaacgaagga gacagcaaga     2160

auagucuacc auauggaaaa auaaauggaa cguacaaagg aacugaaaaa gaaaaaauca     2220

aauucucauc agaaggcagu uucgaucccg acgggaaaau aguaucauac gaaugggauu     2280

uuggagaugg caacaaauca aacgaagaaa acccagaaca uucauaugau aaagucggaa     2340

ccuacacagu aaaacuaaaa guaaccgaug acaagggaga aucaucgguu uccaccacga     2400

cagcugaaau aaaagacuua ucagaaaaca aauuacccgu aauauacaug cacguaccaa     2460

aaucaggcgc gcuuaaccaa aaagugguuu ucuauggaaa aggcacauac gauccagaug     2520

gaagcaucgc aggauaccag ugggauuucg gagaugguuc agauuuuagu ucugaacaaa     2580

auccuagcca uguauacacc aaaaaaggug aauacacagu uacacuuagg guuauggacu     2640

ccucaggaca aaugagcgaa aaaacaauga aaauaaaaau aaccgaccca guauacccaa     2700

uaggaaccga aaaggaacca aacaauucua aagaaacagc aucaggucca auaguaccag     2760

gaaucccagu gucagggaca auagaaaaca caucagacca agacuauuuc uauuucgacg     2820

uaauaacacc cggagaagua aaaauagaca uaaacaaauu aggauacggu ggcgccacuu     2880

ggguuguaua ugacgaaaac aacaacgcag uaucuuaugc aacugacgac ggccaaaacu     2940

uaaguggaaa guuuaaagcc gauaaaccug gacgauacua cauacaccua uacauguuca     3000

acggcaguua caugccauac agaauaaaca uagaagguag cguuggucga uaaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3714
<211>  3520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt13)

<400>  3714
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

ggguaacauu caucagcuua cuauuuuuau uuucaucugc cuauuccaug aaaagaaaau      120

gucuaucaaa aagauuaaug uuagcaauaa caauggcuac aauauucacg gucaacagua      180

cacucccaau auacgcugca gucgacaaaa acaacgcgac ugcagcacgc aggcgcagaa      240

aaagaguaca gaaugaauca aaacgauaca ccgugucgua ccuaaaaacc cuaaauuacu      300

acgaccucgu ugaccuauua guaaaaacag aaauagaaaa uuuaccagac cuuuuucaau      360

acucaagcga ugccaaggaa uuuuacggaa auaaaacaag gaugaguuuc auaauggaug      420

agaucggccg ccgagcacca caauauaccg aaauagauca uaaaggaauc ccgacguugg      480

uugaaguugu uagagcagga uucuauuugg guuuucacaa caaagaacua aaugaaauaa      540

auaaacgcag cuucaaagaa agaguaauac caagcaucuu agcgauucag aaaaauccua      600

auuucaaacu aggaacggaa guacaagaca aaaucgucuc agcaacggga uuguuagcgg      660

gaaacgaaac cgcuccacca gaagucguaa acaacuuuac ccccauacua caagacugca      720

ucaaaaauau agauagauac gcauuagaug auuuaaaauc uaaagcauua uucaacguau      780

uggcggcacc aacauaugau auaacagaau auuuaagagc gacaaaagaa aaaccagaaa      840

acacuccaug guauggcaaa auugacggau uuauaaauga auuaaagaaa uuggcccuau      900

acggaaaaau aaaugacaau aacagcugga ucauugacaa cggaauauac cacauagcuc      960

ccuuaggaaa acuacauagu aacaauaaaa ucgguauaga aacauuaacu gaaguaauga     1020

aaguuuaccc auaucuaagu augcaacauu uacaaucagc agaucaaaua aaaaggcacu     1080

augauagcaa agacgcagag ggaaacaaaa uaccacuaga caaauuuaag aaagagggaa     1140

aagaaaaaua cuguccaaaa accuacacau ucgaugacgg aaaaguaauc auaaaagcag     1200

gagcaagagu agaagaggaa aaaguaaaac gauuauauug ggcaucuaaa gaaguuaauu     1260

cucaauucuu cagaguauac ggaauagaca aaccacuaga agaaggcaau ccagacgaca     1320

uauuaacaau gguaauuuac aacaguccug aagaauauaa auuaaauuca guauuauaug     1380

gauacgacac aaacaaugga ggaauguaca ucgaacccga aggcacauuc uuuaccuacg     1440

aaagagaggc ucaagaaucu acuuauacuc ucgaagaacu uuuuaggcau gaauauacac     1500

acuaucucca agguagauau gccguaccag gacaaugggg uagaacaaaa cuauacgaua     1560

augacagacu uacuugguau gaagaaggag gcgcagaacu auuugcgggc agcacacgua     1620

cuucaggcau ccuaccacga aaauccauag uuuccaacau ccacaauaca acaagaaaca     1680

accgauauaa auuaucagau acuguccacu caaaauacgg ugcguccuuc gaauuuuaca     1740

acuacgcaug uauguuuaug gacuacaugu auaauaaaga uauggguaua cuuaacaaau     1800

ugaaugacuu agccaaaaau aaugauguag acggauacga uaacuacaua agagaccuau     1860

caucaaacua ugcauuaaau gacaaauauc aagaccauau gcaagaaaga auugauaacu     1920

acgaaaacuu aacuguacca uucguagcag augauuacuu aguaagacau gcauauaaaa     1980

auccaaacga aaucuacagc gaaaucagcg aaguagccaa acucaaagau gccaaauccg     2040

aagugaagaa aucacaauac uucucaacau ucacuuuaag agguaguuac acaggaggug     2100

cauccaaagg aaaauuagaa gaccaaaaag ccaugaauaa auuuauagac gacagucuaa     2160

agaaauuaga uaccuacuca uggaguggau acaaaacauu aacagccuac uucacaaacu     2220

acaaaguaga uucaucuaac cgagucaccu acgacguagu auuucauggc uacuuaccaa     2280

acgaaggcga uagcaaaaac ucacuaccgu acggcaaaau uaacggcaca uacaaaggaa     2340

cagaaaaaga gaaaaucaaa uucuccuccg aagguagcuu cgacccagac gguaaaaucg     2400

uaaguuauga augggauuuc ggugacggca acaaaucgaa cgaagaaaac ccagaacaca     2460

gcuaugauaa aguagguaca uauacaguca aacuaaaagu aaccgaugau aaaggugaau     2520

cgucugucuc aacgaccaca gccgaaauaa aagauuuguc cgaaaauaaa uuaccaguca     2580

ucuauaugca ugucccaaaa ucaggagccc uaaaccaaaa agugguuuuc uauggaaaag     2640

gaacauacga cccugaugga ucaauagcag gcuaucaaug ggauuucggu gacggcucag     2700

acuuuagcag ugaacaaaau ccaucgcaug uguacacaaa gaaaggagaa uacacaguaa     2760

cacuacgagu cauggauucu uccggacaaa ugagugagaa aacgaugaaa auuaaaauaa     2820

cagacccagu auacccaaua ggaacagaaa aagaaccaaa uaacuccaaa gaaaccgcau     2880

cuggaccaau aguccccgga auaccaguaa gcggcacuau cgaaaauaca ucagaccaag     2940

acuauuuuua cuuugacgua auaaccccag gagaaguaaa aauagacaua aauaaauuag     3000

gauacggcgg cgcuacaugg guaguuuacg acgaaaacaa caaugcagua ucauacgcaa     3060

cagaugacgg acaaaacuua aguggaaaau uuaaagcuga caaaccagga agauauuaca     3120

uacauuuaua uauguucaau ggauccuaua ugccauacag aaucaacaua gaaggaagcg     3180

uaggaaggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     3240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     3300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     3360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     3480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           3520


<210>  3715
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt13)

<400>  3715
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauauu auucgcaugc cuacuaggag cagcauucgc aaugccacua ccaccacacc      120

caggacaccc aggauacaua aacuucucau acgaaguacu aacaccacua aaaugguacc      180

aaucaauacg acccccauac ccaucauacg gauaugaacc caugggagga uggcuacacc      240

accaaauaau accaguacua ucacaacaac aucccccaac acacacauua caaccucacc      300

accacauacc aguaguacca gcacaacaac caguaauacc acaacaacca augaugccag      360

uaccaggaca acacucaaug acaccaauac aacaccacca accaaaccua ccaccaccag      420

cccaacaacc auaccaacca caaccaguac aaccacaacc acaccaacca augcaaccac      480

aaccaccagu acacccaaug caaccacuac caccacaacc accacuacca ccaauguucc      540

caaugcaacc acuaccacca augcuaccag accuaacacu cgaagcaugg ccaucaaccg      600

auaaaacaaa aagagaagaa guagacuaag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  3716
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt13)

<400>  3716
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaucaaua agaccaccau acccaucaua cggauacgaa ccaaugggag      180

gaugguaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  3717
<211>  550
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt13)

<400>  3717
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaucaaua agaccaccac caaugcuacc agaccuaaca cuagaagcau      180

ggccaucaac agacaaaaca aaaagagaag aaguagacua aggacuagug caucacauuu      240

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      300

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      360

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      420

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      540

caccagaauu                                                             550


<210>  3718
<211>  589
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt13)

<400>  3718
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacacua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc auacccauca uacggauacg      240

aaccaauggg aggaugguaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      300

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      360

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      420

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      540

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  589


<210>  3719
<211>  622
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt13)

<400>  3719
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacacua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc accaaugcua ccagaccuaa      240

cacuagaagc auggccauca acagacaaaa caaaaagaga agaaguagac uaaggacuag      300

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      360

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      420

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      480

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      600

ucuuuucaga gccaccagaa uu                                               622


<210>  3720
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt13)

<400>  3720
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu auucgcaugc cuaguaggag ccgcauucgc aaugccacua ccaccacauc      120

caggacaccc aggauauaua aacuucucau acgaaguauu aacaccacuc aaaugguacc      180

aauccaugau aagaccccca uacucaucau acggauacga accaaugggc ggauggcuac      240

accaccaaau aaucccagua guaucccaac aacacccacu aacacacaca uuacaaucac      300

accaccacau accaguagua ccagcacaac aaccaagagu aagacaacaa gcauuaaugc      360

caguaccagg acaacaauca augacaccaa cacaacacca ccaaccaaac cuaccacuac      420

cagcacaaca acccuuccaa ccucaaccag uacaaccaca accacaccaa ccaaugcaac      480

cacaaccacc aguacaacca augcaaccac uauuaccaca accaccacua ccacccaugu      540

ucccacuaag accauuacca ccaauacuac cagaccuaca ccuagaagcc uggccagcaa      600

cagacaaaac aaaacaagaa gaagucgacu aaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  3721
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt13)

<400>  3721
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaucaaug auaagaccac cauacucauc auacggauac gaaccaaugg      180

gaggauggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3722
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt13)

<400>  3722
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaucaaug auaagaccac caccaauacu accagaccua caccuagaag      180

cauggccagc aacagacaaa acaaaacaag aagaaguaga cuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3723
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt13)

<400>  3723
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacacua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua uauaaauuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaucaaucaa ugauaagacc accauacuca ucauacggau      240

acgaaccaau gggaggaugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3724
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt13)

<400>  3724
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacauua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaucaaucaa ugauaagacc accaccaaua cuaccagacc      240

uacaccuaga agcauggcca gcaacagaca aaacaaaaca agaagaagua gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3725
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt13)

<400>  3725
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu auucgcaugc cuacuaggag cagcauucuc aaugccacua ccaccacacc      120

caggacaucc aggauacaua aacuucucau acgaaguacu cacaccauua aaaugguacc      180

aaaacaugau aagacaccca uacacaucau acggauacga accaaugggc ggauggcuac      240

accaccaaau aauaccagua guaucacaac aaaccccaca aucacacgca uuacaaccac      300

accaccauau accaauggua ccagcacaac aaccaggaau accacaacaa ccaaugaugc      360

cacuaccagg acaacacuca augacaccaa cccaacacca ccaaccaaac cuaccccuac      420

ccgcacaaca accauuccaa ccacaaccag uacaacccca accacaccaa cccuuacaac      480

cacaaucacc aaugcaccca auacaaccac uacucccaca accaccacua ccaccaaugu      540

ucucaaugca aucacuacua ccagaccuac cauuagaagc auggccagca acagacaaaa      600

caaaaagaga agaaguagac uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3726
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt13)

<400>  3726
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaaauaug auaagacacc cauacacauc auacggauac gaaccaaugg      180

gaggauggua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  3727
<211>  553
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt13)

<400>  3727
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaaacaug auaagacacc caucacuacu accagaccua ccauuagaag      180

cauggccagc aacagacaaa acaaaaagag aagaaguaga cuaaggacua gugcaucaca      240

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      300

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      360

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      420

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      540

agccaccaga auu                                                         553


<210>  3728
<211>  592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt13)

<400>  3728
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacauua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cauccaggac acccaggaua uauaaauuuc ucauacgaag      180

uauuaacacc acuaaaaugg uaucaaaaua ugauaagaca uccauauaca ucauacggau      240

acgaaccaau gggaggaugg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      300

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      360

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      420

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      540

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              592


<210>  3729
<211>  625
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt13)

<400>  3729
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

uaauggcacc aagaacauua guacuacuac uaucaggagc acuagcacua acacaaacau      120

gggcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaaaca ugauaagaca cccaucacua cuaccagacc      240

uaccacuaga agcauggcca gcaacagaca aaacaaaaag agaagaagua gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      600

ggcucuuuuc agagccacca gaauu                                            625


<210>  3730
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt13)

<400>  3730
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu auucgcaugc cuauuaggag cagcauucuc aaugccacua ccaccacacc      120

caggacaccc aggauauaua aacuucucau acauaagaca cccauacaca ucauacggau      180

acgaaccaau gggaggaugg cuacaccacc aaauaauucc aguaguauca caacaaacac      240

cacaaucaca cgcacuacaa ccacaccacc acauaccaau gguaccagca caacaaccag      300

gaauaccaca acaaccaaug augccacuac ccggacaaca cucaaugaca cccacacaac      360

accaccaacc aaaccuacca cuaccagcac aacaaccauu ccaaccacaa ccaguacaac      420

cacaaccaca ccaaccauua caaccacaau caccaaugca cccaauacaa ccacuacuac      480

cacaaccacc acuaccaccc auguucucaa ugcaaucacu acuaccagac cuaccacuag      540

aagcauggcc agcaacagac aaaacaaaaa gagaagaagu agacuaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  3731
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt13)

<400>  3731
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauauu cuucgcaugc cuauuaggag caucccuagc aaugccacua ccaccacacc      120

caggacaccc aggauacaua aacuucucau acgaaguacu cacaccauua aaaugguacc      180

aaaacaugau aagacaccca uacacaucau acggauacga accaauggga ggcuggcuac      240

accaccaaau aauaccagua guaucacaac aaacaccaca aucacacgca cuacaaccac      300

aucaccacau accaauggua ccagcccaac aaccaggaau accacaacaa ccaaugaugc      360

cacuaccagg acaacacuca augacaccaa cacaacacca ccaaccaaac cuaccacuac      420

cagcacaaca accauuccaa ccacaaccag uacaaccaca accccaccaa ccacuacaac      480

cacaaucacc aaugcaccca auccaaccac uacuaccaca accaccacua ccaccaaugu      540

ucucaaugca aucccuacua cccgaccuac cacuagaagc cuggccagca acagacaaaa      600

caaaaagaga agaaguagac uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  3732
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt13)

<400>  3732
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu auucgcaugc cuacuaggag cagcauucuc aaugccacua ccaccacacc      120

caggacaccc aggauacaua aacuucucau acgaaguacu aacaccacua aaaugguauc      180

aaaacaugau aagacaccca ucacuauuac cagaccuacc acuagaagca uggccagcaa      240

cagacaaaac aaaaagagaa gaaguagauu aaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  3733
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt13)

<400>  3733
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu auucgcaugc cuauuaggag cagcauucuc aaugccacua ccaccacacc      120

caggacaccc aggauacaua aacuucucau acgaagaccu auacuuagaa gcaauaagaa      180

uagacagaac agcauucgua cuaacaccac uaaaauggua ccaaaacaug auaagacacc      240

cauacacauc auacggcuac gaaccaaugg gaggauggcu acaccaccaa auaauaccag      300

ucguauccca acaaacaccc caaucacacg cauuacaacc acaccaccac auaccaaugg      360

ucccagcaca acaaccaggu auaccccaac aaccaaugau gccacuacca ggacaacacu      420

caaugacacc aacacaacac caccaaccaa accuaccacu accagcacaa caaccauucc      480

aaccacaacc aguacaacca caaccacacc aaccacuaca accacaauca ccaaugcacc      540

caauacaacc acuacuacca caaccaccau uaccacccau guucucaaug caaucacuau      600

uacccgaccu uccacuagaa gcauggccag caacagacaa aacaaaaaga gaagaaguag      660

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  3734
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt13)

<400>  3734
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

cauggauacu cuucgcaugc cuacuaggcg cagcauucuc caugccacua ccaccacacc      120

caggacaccc cggauacaua aacuucucau acgaaguacu cacaccacua aaaugguacc      180

aaaacaugau aagacaccca acaccacaau cacacgcacu acaaccacac caccacauac      240

caaugguacc ugcacaacaa ccaggaauac cacaacaacc aaugaugcca cuaccaggcc      300

aacacuccau gacacccaca caacaccacc aaccaaaccu accacuacca gcccaacaac      360

cauuccaacc acaacccgua caaccacaac cacaccaacc auuacaaccc caaucaccaa      420

ugcacccaau acaaccacua cucccacaac caccacuacc accaauguuc ucaaugcaau      480

cacuacuacc agaccuacca cuagaagcau ggccagcaac agacaaaaca aaaagagaag      540

aaguagacua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  3735
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt13)

<400>  3735
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

uaccaccaca cccaggacac ccaggauaca uaaacuucuc auacgaagua cuaacaccac      120

uaaaauggua ccaaaacaug auaagacacc ccuacacauc auacggauac gaaccaaugg      180

gaggauggcu acaccaccaa auaauaccag uaguaucaca acaaacacca caaucacacg      240

cacuacaacc acaccaccac auaccaaugg uaccagccca acaaccaggc auaccacaac      300

aaccaaugau gccacuacca ggacaacacu caaugacacc aacacaacac caccaaccaa      360

accuaccacu accagcacaa caaccauucc aaccacaacc aguacaacca caaccacacc      420

aaccacucca accacaauca cccaugcacc ccauacaacc auuacuacca caaccaccac      480

ucccaccaau guucuccaug caaucacuac uaccagaccu accacuagaa gcauggccag      540

caacagacaa aacaaaaaga gaagaaguag acuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  3736
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt13)

<400>  3736
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

guguagcacg ucuaccauua uugcuagguu uauugcuacu accccgaccg ggacgaccac      120

uagacuuagc cgauuacaca uaugaccuag cagaagagga cgauagugaa ccauuaaacu      180

acaaagaucc auguaaagcu gccgcauucu uaggugauau agcuuuagac gaagaagauu      240

uacgugcauu ucaaguccag caagcaguag auuuacguag acauacugca cgcaaaaguu      300

caauaaaagc agcuguacca ggaaacacau caacaccuuc cugucaauca acaaaugguc      360

aaccucaaag aggggcuugc ggacguugga gggggagaag uagaaguaga cgugcagcaa      420

caagucgacc agaacgagua uggccagaug gaguaauucc auuuguaauu gguggaaacu      480

uuacuggauc acaaagagcu guauucaggc aagcuaugag acauugggaa aaacauacuu      540

gcguuacauu cuuagaacga acagaugaag auuccuauau aguauuuacu uauagaccuu      600

gugggugcug uaguuaugug gguagaagag gggguggacc acaagcaaua ucaauuggua      660

aaaauuguga caaauuugga auaguuguac augaacuagg acauguagua ggauuuuggc      720

acgaacauac aagaccagau agagacagac auguauccau aguuagagaa aauauacaac      780

caggacaaga auauaauuuc cuaaaaaugg agccacagga aguagagagu uugggagaaa      840

cuuacgacuu cgacaguaua augcauuaug caagaaauac uuuuucacga ggaauauucc      900

uagauacuau ugugccuaaa uacgaaguga augguguaaa accuccaauu ggucaaagga      960

cuagguuaag caaaggagau auagcacaag cgcgcaaacu uuauaaaugu ccagcaugug     1020

gugaaacauu acaggacuca acaggaaauu uuucaucacc ugaauacccu aacggguaua     1080

gugcacauau gcacugugua uggagaauau caguaacacc aggagagaaa auaauauuaa     1140

acuucacuag ccuggaucuu uauagaucga gacucuguug guaugauuau guagaaguua     1200

gagauggcuu cuggagaaaa gcaccauuga gagggcguuu uuguggcagu aaacuaccag     1260

aaccaauagu aucuacagau uccagauuau gggucgaguu cagaaguuca uccaauuggg     1320

uaggaaaagg uuucuucgcc guauaugaag cgauaugcgg aggggaugua aagaaagacu     1380

auggucauau acaaagcccu aauuauccug augacuauag gccaaguaaa guuuguauuu     1440

ggagaauaca agugucagaa gguuuucacg uuggacucac auuucaaucu uuugaaauag     1500

agcgccauga cucaugugcg uaugacuauu uagagguaag agacggacau ucagaaucuu     1560

cuacucuuau aggaagauau uguggauaug agaaaccaga ugauauaaaa aguacaaguu     1620

cucgacuaug guuaaaauuu guaagcgaug gaagcauaaa uaaagcagga uuugcaguaa     1680

auuucuuuaa agaaguugau gaaugcucga gaccuaauag agggggaugc gaacaacgau     1740

gucuaaauac acucggaagc uacaaaugua gcugugaucc aggauaugaa cuugcaccgg     1800

acaaaagaag augugaagcu gcaugcggcg gauuucuaac caaacucaau ggaucaauua     1860

cuuccccagg auggccuaaa gaauauccac cgaauaaaaa cugcauaugg caauuaguag     1920

cuccaacaca auaucgcauc agcuuacaau uugacuucuu ugaaacugag ggaaaugaug     1980

uuuguaaaua ugacuuuguc gaagucagau caggccucac agcagauucu aaauuacacg     2040

gcaaauuuug uggaagcgaa aaaccggaag uaauaacauc acaauacaau aacaugagag     2100

uagaguuuaa aagcgauaau acaguaagua agaaaggauu uaaagcacac uucuucucag     2160

auaaagacga auguucaaaa gacaaugggg gaugucaaca agacugugua aauacguuug     2220

gaucauauga augucaaugc cgaaguggau ucguacuuca ugauaauaaa caugauugua     2280

aagaagcagg uugcgaucac aaaguuacau caacuucagg cacaauaacu ucaccuaacu     2340

ggccagauaa auauccauca aagaaagaau guacaugggc aauaucuuca accccagguc     2400

aucgcguaaa auuaacauuu auggaaaugg auauugaauc acaaccagaa ugugcauaug     2460

aucacuuaga aguauucgac ggaagggaug caaaagcacc aguauuaggu agauuuugug     2520

gcaguaagaa accagaacca guucuugcga caggaagccg uauguuuuua agauuuuacu     2580

cagauaauuc cguacaaaga aaaggauuuc aagccuccca ugcgacggaa uguggaggac     2640

aaguacgagc agauguuaaa accaaagacc uauacucaca cgcacaauuu ggugauaaua     2700

auuacccagg ugggguagac ugcgaauggg uaauaguagc agaagaaggg uacggaguug     2760

aauuaguauu ccaaacauuu gaaguagaag aagaaaccga uuguggcuau gauuauaugg     2820

aacuauucga cggauacgac uccacagcac cgagauuagg acgauacugu ggaaguggac     2880

caccagaaga aguuuauuca gcaggagacu cagucuuagu gaaauuucau ucggacgaca     2940

caauaaccaa gaaaggauuc cacuuaagau acacuucaac uaaauuccaa gauacacuac     3000

acaguagaaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  3737
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt13)

<400>  3737
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucg       60

ccggaaccag augccuauua gcccuacuau uaccacaagu ucuacuaggu ggagcugcag      120

gauuaguacc agaacuagga agacgaaaau ucgcggcagc auccucagga agaccaucau      180

cacagccauc agacgaagua cuauccgaau ucgaacuaag guuauuaucu auguuuggau      240

uaaaacaaag accaacgcca ucuagagacg cagucguucc accauacaug cuagaucuau      300

auagaagaca cuccggacaa ccaggauccc cagcacccga ucauagauua gaacgagccg      360

caucacgugc aaacaccgua agauccuucc accacgaaga aucucuagaa gaacuaccag      420

aaacaucagg aaaaacuaca agaagauucu ucuuuaaccu aucaucuauc ccaacagaag      480

aauucaucac aucagcagaa uuacaagucu uuagagaaca aaugcaagac gcauuaggaa      540

auaacucauc auuucaccac agaauuaaca uauacgaaau aaucaaacca gcaaccgcaa      600

acagcaaauu cccagucacu cgauuacuag auacaagacu aguuaaccaa aacgcaucaa      660

gaugggaauc auuugacgua acucccgcag uuaugagaug gacagcacaa ggacacgcaa      720

aucacggauu ugucguugaa guagcccauu uagaagaaaa acaaggaguu ucaaaaagac      780

acguccgcau aagcagauca cuacaucaag acgaacauuc uuggagucaa auaagaccac      840

uacuuguaac auucggccac gacggaaaag gacacccauu acacaaaaga gaaaaaagac      900

aagcaaaaca caaacaaaga aaaagacuaa aaucaucaug caaaagacau ccauuauacg      960

uagauuucuc agauguagga uggaacgacu ggauaguagc accaccagga uaccacgcau     1020

uuuacugcca uggagaaugc ccauuuccac uagcagacca ccucaacuca accaaccacg     1080

caauaguuca aacccuagua aauucaguaa auucaaaaau accaaaagca ugcugugucc     1140

caacagaacu uucugcaaua ucaaugcuau auuuagauga aaacgaaaaa guaguucuaa     1200

aaaauuacca agacaugguc guagaaggau gcggauguag auaaggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  3738
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt13)

<400>  3738
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauac       60

caggaaauag aaugcucaug guaguauuau uaugccaagu acuucuaggu ggagcuucac      120

augcaucacu uauaccagaa accggaaaaa aaaaaguagc agaaauacaa ggacaugccg      180

gaggaagaag auccggacaa ucacaugaau uacuacgaga uuuugaggcc acuuuauuac      240

agauguucgg auuaagaaga cgaccucaac caucaaaauc agcaguaauu ccagacuaca      300

ugcgagaucu auacagauua caaucaggag aagaagaaga agaacaaaua cacaguaccg      360

gacuagaaua cccagaaaga ccagcaucaa gagccaauac cguuagauca uuccaccaug      420

aagaacauuu agaaaauaua ccaggaacau cagaaaauuc agcuuucaga uuuuuauuca      480

auuuaagcag cauaccagaa aacgaaguca uaucaucagc agaacuaaga cuauuuagag      540

aacaaguuga ccaaggaccu gacugggaac gcggauucca cagaauaaau auauacgaag      600

uaaugaaacc accugcugaa guaguaccag gacaccuaau aacuagauua cuagauacaa      660

gacuaguaca ccauaaugua acaagguggg aaacauuuga cguaucaccg gcaguauuac      720

gguggacaag agaaaaacaa ccaaauuacg gacuagcaau agaagucaca cacuuacauc      780

aaacaagaac acaucagggu caacacguaa gaauaucacg aucacuucca caagguucag      840

guaacugggc ccaauuaaga ccauuacuag uaacauuugg acaugacgga agaggacacg      900

ccuuaacacg aaggcgaaga gccaaaagaa guccaaaaca ccauucacaa agagcacgaa      960

aaaaaaacaa aaauugccga agacauucac uauacguaga cuuuucagau gucggaugga     1020

augacuggau cguagcacca ccaggcuacc aagcauuuua cugucacgga gauugcccau     1080

uuccacuagc agaucacuua aacucaacca aucacgcaau aguacaaaca cuaguaaauu     1140

cuguaaacag cucuauacca aaagcuuguu guguaccaac agaacuauca gccauaucua     1200

uguuauaucu agaugaauau gauaaaguag uauuaaaaaa cuaucaagaa auggucguag     1260

aaggaugcgg auguagauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  3739
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt13)

<400>  3739
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gauuaggaag acgagcacaa uggcuaugcu gguggugggg uuuauuaugu agcuguugcg      120

guccaccacc uuuaagacca ccauuaccag ccgcagcugc ugcugcagca ggcggucaac      180

uauuaggaga ugggggauca cccgggagaa cagaacaacc cccaccauca ccccaaagcu      240

caucaggguu cuuauacaga agauuaaaaa cacaagaaaa acgcgaaaug caaaaagaaa      300

uacuaagugu auuaggauug ccacauagac cuagaccauu acauggauua caacaaccac      360

aaccuccagc uuuaagacaa caagaagaac aacaacaaca acaacaauua cccagaggag      420

aaccaccccc aggaagacua aaaucugcuc cauuauucau gcuagaccua uacaaugcac      480

uaagcgcaga caaugacgaa gauggagcuu cugaaggaga aagacaacaa ucauggccuc      540

augaagcagc uucaagcagu caaaggagac aaccaccacc aggagcagca cacccacuua      600

aucgaaaaag ccuacuagca cccggcucug gaucaggagg cgcaagucca uuaacaucag      660

cacaagauag cgcguuuuua aaugacgcag acaugguaau gucauucgug aauuuaguag      720

aauacgauaa agaauuuucu ccaagacaaa gacaccacaa agaguucaaa uucaaucuau      780

cccaaauacc ugaaggagaa guaguaacug cagcagaauu uagaaucuac aaagacugug      840

uaaugggauc auucaaaaau caaacuuucu uaauaucuau cuaccaagua uuacaagaac      900

aucaacauag agacucugau uuauuccucu uagacacaag aguuguaugg gcaucagaag      960

aagguuggcu agaauuugac auuacugcaa caucaaacuu auggguagua acaccacaac     1020

auaacauggg acuacaauua ucagucguaa ccagagaugg uguucaugua cacccuagag     1080

cugcaggacu uguaggcaga gacggaccau acgauaaaca accauucaug guagcauucu     1140

ucaaaguauc agaaguacau guaagaacaa cacgaucugc uagcucaaga agaagacaac     1200

aaagucgcaa cagaucuaca caaucacaag auguagcacg aguaucaucu gcuucagacu     1260

auaacuccuc cgaacuaaaa acagcaugca ggaaacacga auuauacguu uccuuccaag     1320

auuuaggaug gcaagacugg auaauagcac ccaaaggaua cgcugcaaac uacugcgacg     1380

gugaauguuc auuuccauua aaugcacaua ugaacgcaac aaaccaugca aucguacaaa     1440

cucuaguaca ccuaaugaau ccagaauaug uccccaaacc auguugcgca cccacaaaac     1500

uuaacgcaau aucagucuua uacuuugacg acaauucaaa uguaauccua aagaaauaua     1560

gaaacauggu agucagagcc ugcgguugcc auuaaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  3740
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt13)

<400>  3740
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaug       60

uaagaucacu aagagcagcu gccccacacu cauuuguagc acugugggca ccacuuuuuu      120

uacuaagaag cgcauuagca gacuuuucac uagacaauga aguacauuca agcuuuauuc      180

auaggagacu ucggucacaa gaaagacgug aaaugcaaag agaaauauua ucuauucuag      240

gacuaccaca ccgcccaaga ccacaucuac aaggaaaaca caauucagcu ccaauguuca      300

ugcuagaucu uuauaacgca auggcagucg aagaaggagg aggccccgga ggacaaggau      360

uuuccuaucc auauaaagca guauuuucaa cacaaggacc uccucuagca agucuacaag      420

auucacauuu cuuaacagau gcagauaugg uaaugucauu uguaaauuua guagaacaug      480

auaaagaauu uuuucaccca cguuaccacc auagagaauu cagauucgau cuaucuaaaa      540

uaccagaagg ugaagcagua acagcagcug aauucagaau auacaaagau uacauacgag      600

aaagauuuga caacgaaaca uucagaauau caguauauca aguacuacaa gaacacuuag      660

guagagaaag cgaucuauuu cuauuagacu ccagaacacu cugggcauca gaagaaggcu      720

ggcuaguauu cgauauaaca gcaaccagua aucacugggu cguaaaccca agacacaacc      780

ucggacuaca auuaucagua gaaacauuag acggccaaag uauuaaccca aaacucgcag      840

gacuaauagg aagacacgga ccacaaaaca aacaaccauu caugguagca uucuuuaaag      900

caaccgaagu acacuucaga ucaauacgau caacaggauc caaacaaaga agccaaaaua      960

gaucaaaaac uccaaaaaau caagaagcau uaagaauggc aaauguagcu gaaaauucau     1020

caagugauca aagacaagcc ugcaaaaaac acgaauuaua cguauccuuc cgagauuuag     1080

gauggcaaga cuggauaaua gcaccugaag gcuacgccgc auacuacugu gaaggagaau     1140

gugcauuucc cuuaaacuca uauaugaacg caacuaauca cgcuauagua caaacacuag     1200

uacacuuuau aaaucccgaa acaguaccca aaccaugcug cgcaccaaca caacucaacg     1260

cuauaucagu auuauauuuu gacgacucuu cuaacguuau ccuaaaaaaa uaucgaaaua     1320

ugguagucag agcauguggc ugccacugag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  3741
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt13)

<400>  3741
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaag       60

caucagcagc acuacuaugc cuacuacuaa cagcagcagc auucucacca caaggacuag      120

cacaaccagu aggaauaaac acaucaacaa caugcugcua cagauucaua aacaaaaaaa      180

uaccaaaaca aagacuagaa ucauacagaa gaacaacauc aucacacugc ccaagagaag      240

caguaauauu caaaacaaaa cuagacaaag aaauaugcgc agacccaaca caaaaauggg      300

uacaagacuu caugaaacac cuagacaaaa aaacacaaac accaaaacua uaaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  3742
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt13)

<400>  3742
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguugc       60

uuacuuuaau aauauuacuu ccaguuguca guaaauuuuc guuuguguca uuaucugcac      120

cacaacauug gaguugucca gaagguacgc uagcaggcaa cgguaauucu acgugugucg      180

guccagcgcc auuucuaauc uuuucucaug guaacuccau uuuuagaaua gauacagaag      240

guacaaauua cgaacaauua guaguugacg caggagucag cguaauaaug gacuuucauu      300

auaaugagaa aagaaucuau uggguagacu uggaaagaca auuacuucag cguguauucu      360

ugaauggauc cagacaagaa agaguaugua auauagagaa aaauguauca gguauggcua      420

uaaacuggau aaaugaagaa gugauuuggu caaaucaaca agaagggauc auuaccguua      480

cagacaugaa aggaaauaau ucccacauac uacuaucagc acuaaaauau cccgccaaug      540

uugcaguaga uccaguggaa agauuuauau uuugguccuc agaaguagca ggaucauuau      600

auagagcaga cuuagacggu guggguguua aggcuuuacu agaaacuucu gagaaaauua      660

ccgcaguaag uuuagacguu uuagacaaaa gauuauuuug gauucaauau aauagggaag      720

guucaaauuc acuuauaugu ucuugcgacu augauggugg aucagugcau auaaguaaac      780

auccaacgca acacaaucuc uuugcaaugu cuuuauuugg ugauagaaua uuuuacagca      840

cuuggaaaau gaaaacaaua uggauagcca acaaacauac cggaaaagau augguaagga      900

uaaaucuaca caguuccuuc guuccuuuag gugaacuaaa aguaguacau ccacuagcgc      960

aaccuaaagc ggaagaugac acuugggaac cagaacaaaa acuauguaag uuacgaaaag     1020

gcaacuguuc aucuacagug ugcgggcaag acuuacaaag ucacuuaugu augugcgcgg     1080

aaggcuaugc gcucaguaga gauagaaaau auugugaaga uguaaaugaa ugugcauuuu     1140

ggaaccaugg auguacacua ggaugcaaaa auacaccagg uucauauuau uguacuuguc     1200

ccguuggauu uguccuguua ccagacggca aaaggugcca ucagcuagua aguuguccac     1260

guaauguuuc agaauguagc cacgauugug uuuugacaag ugaaggacca cuaugcuuuu     1320

gcccagaagg aucaguauua gaaagggaug gaaaaacaug uagugguugu aguucaccag     1380

auaauggagg uuguagucaa cuuuguguuc cauuaucucc uguaucuugg gaaugcgauu     1440

guuucccagg uuaugauuua caauuagaug agaaaaguug ugcagcgucu ggcccacaac     1500

cauucuuacu cuuugcaaau ucacaagaua uaagacacau gcauuucgau ggcaccgacu     1560

acggcacccu auuaagucaa caaaugggga ugguauaugc acuugaccau gauccaguag     1620

aaaacaaaau auacuucgca cauaccgcac ucaaauggau cgaaagagca aauauggacg     1680

gaagucaaag ggaacgguug auugaagaag gaguagaugu accugagggu uuagcaguug     1740

auuggauagg gaggagauuu uauuggacgg acagggggaa aaguuuaaua ggacgaagcg     1800

accucaacgg gaaaagaagc aaaauaauca cuaaagaaaa uauuucacaa ccaagaggaa     1860

uugcuguaca uccaauggca aaacgucuau uuuggacaga cacaggaaua aauccuagaa     1920

uagaguccag uucacugcaa ggauugggga gauuagugau cgccaguucc gaccuaauau     1980

ggccaucggg aauuacaaua gacuuuuuaa ccgauaaacu auauuggugc gaugcaaaac     2040

agucaguaau ugaaauggcc aaucuagaug gaucuaaaag aagaagacua acacaaaaug     2100

augugggaca cccauuugcu guugccguuu ucgaggacua cgucugguuu ucagauuggg     2160

caaugccaag ugucaugaga gucaauaaga gaacugguaa ggauagaguc agauuacaag     2220

gcucaauguu aaaaccaucg agucuagucg uaguccaccc auuagcaaaa ccaggugcag     2280

aucccugcuu auaucaaaau ggagggugcg aacacauaug uaagaaaaga cuuggcacag     2340

caugguguuc auguagagaa ggauuuauga aggcuucaga uggaaaaacc uguuuagcau     2400

uagauggcca ucaacuucuc gccggaggag aaguugacuu gaaaaaccaa guaacacccc     2460

uagauauauu aagcaaaaca agaguuagcg aagauaacau aacagaaucu caacauaugu     2520

uaguagcaga aauuaugguc ucagaucaag augacugcgc accuguagga uguucuaugu     2580

augcuagaug cauaucagag ggggaagaug cgacauguca augcuuaaaa ggauuugcag     2640

gcgacggaaa auuaugcuca gacauagacg aaugugaaau gggaguuccu guuuguccuc     2700

cagcaucuuc caaauguaua aauaccgaag gugguuaugu auguagaugu agugaaggau     2760

accaagggga cgguauccau uguuuagaua uagaugaaug ccaauuggga gaacacuccu     2820

guggagagaa cgcauccugu acaaauacug aaggagguua uacguguaug ugcgcaggaa     2880

ggcuuuccga accugguuua auuugcccag auucaacacc ucccccacac cuucgugaag     2940

augaccacca uuauagugua cgaaauucag auucugagug cccacuaagc caugauggau     3000

auuguuuaca cgauggagua ugcauguaca uagaagcguu ggauaaauac gcuuguaauu     3060

gugugguugg auacauaggu gaaagauguc aauaccgaga ccuaaaaugg ugggaacuaa     3120

gacaugccgg gcacggacaa caacaaaaag uaauagucgu ugcagugugu guaguagucu     3180

uagucaugcu auuacuauug agccucuggg gugcacacua uuauaggaca caaaaacuac     3240

uaucuaaaaa ccccaaaaau ccauaugaag aaucaagucg ugaugucaga ucaagaagac     3300

cagcagacac agaagacgga augucaucgu guccacaacc augguuugug guaauuaaag     3360

aacaucaaga ucucaaaaac ggaggccaac ccguugcugg ugaagaugga caagcagcag     3420

augguaguau gcagcccaca ucauggcgac aagagccaca auuaugcggc augggaacag     3480

aacaagguug uuggauucca guuaguucug acaaaggaag cuguccgcaa gugauggaga     3540

ggucauuuca uaugccaagc uacggaacac agacacucga aggcggagua gagaaaccac     3600

auucgcuucu uucugcaaac ccauuauggc aacaaagagc ucuagaucca ccucaccaaa     3660

uggaauugac ucaauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  3743
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt13)

<400>  3743
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugacag       60

caggcagaag aauggaaaug cuaugugcag gacgaguacc agcauuauua cuaugucuag      120

gauuccauuu auuacaagca guacuaagca caacaguaau accaagcugu auaccaggag      180

aaagcucaga caauugcaca gccuuaguac aaacagaaga caauccaaga guagcacaag      240

uaaguauaac aaaaugcuca agcgauauga auggauauug cuuacacgga caauguauau      300

aucuaguaga caugagccaa aacuauugca gaugcgaagu cggauacaca ggaguaagau      360

gugaacauuu cuucuuaaca guacaucaac cacuaucaaa agaauacgua gcauuaacag      420

uaauauuaau aauacuauuu cuaauaacag uaguaggaag cacauacuau uucuguagau      480

gguacagaaa cagaaaaucg aaagaaccaa aaaaagaaua cgaacgagua acaucaggag      540

auccagaacu accacaagua uaaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  3744
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt13)

<400>  3744
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

aaggagaaau aacaacauuc acagcacuaa cagaaaaauu caaccuacca ccaggaaacu      120

acaaaaaacc aaaacuacua uacugcucaa acggaggaca cuuccuaaga auacuaccag      180

acggcacagu agacggaaca agagacagau ccgaccaaca cauacaacua caacuaucag      240

cagaaucagu aggagaagua uacauaaaau caacagaaac aggacaauac cuagcaaugg      300

acacagacgg acuacuauac ggaucacaaa caccaaacga agaaugccua uuccuagaaa      360

gacuagaaga aaaccacuac aacacauaca uaucaaaaaa acacgcagaa aaaaacuggu      420

ucguaggacu aaaaaaaaac ggaagcugca aaagaggacc aagaacacac uacggacaaa      480

aagccauacu auuccuacca cuaccaguau caucagacua aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  3745
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt13)

<400>  3745
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguag       60

gaguaggagg gggagaugua gaagauguaa caccaagacc agguggaugu caaauuagcg      120

gaagaggugc aagaggaugu aauggaauac caggagcagc agcuugggaa gcagcauuac      180

cgagaagacg accgagaaga cauccgagug ugaauccaag aucaagagca gcuggaagcc      240

caagaacaag aggaagaaga acagaagaaa gaccaagugg aagcagauua ggagauagag      300

gaagaggacg agcauuacca ggaggaagau uaggaggaag aggaagagga agagcaccag      360

agagaguagg agggagagga agaggaagag gaacagcagc gccaagagca gcaccagcag      420

caagaggauc aagaccagga ccagcaggaa caauggcagc gggaaguaua acaacauuac      480

cagcucuacc agaagaugga ggaagugggg cguuuccacc aggacauuuu aaagauccaa      540

aaagauuaua uuguaaaaau ggaggauuuu uuuuaagaau acauccagau ggaagaguag      600

augggguaag agaaaaauca gauccacaua uaaaauuaca auuacaagcg gaagaaagag      660

gagugguaag uauuaaagga guuugugcaa auagauauuu ggcgaugaaa gaagauggga      720

gguuauuagc aaguaaaugu guaacggaug aauguuuuuu uuuugaaaga cuagaaagca      780

auaacuauaa cacauauaga ucgagaaaau acacaucaug guauguagca uuaaaaagaa      840

caggacaaua uaaacuagga aguaaaacag gaccaggaca aaaagcaaua uuauuuuuac      900

caaugagugc aaagaguuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  3746
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt13)

<400>  3746
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aauggauacu aacauggaua cuaccaacac uacuauacag aagcugcuuc cacauaauau      120

gccuaguagg aacaauauca cuagcaugca acgacaugac accagaacaa auggcaacaa      180

acguaaacug cucaucucca gaaagacaca caagaucaua cgacuacaug gaaggaggag      240

acauaagagu aagaagacua uucugcagaa cacaauggua ccuaagaaua gacaaaagag      300

gaaaaguaaa aggaacacaa gaaaugaaaa acaacuacaa cauaauggaa auaagaacag      360

uagcaguagg aauaguagca aucaaaggag uagaaucaga auucuaccua gcaaugaaca      420

aagaaggcaa acuauacgca aaaaaagaau gcaacgaaga cugcaacuuc aaagaacuaa      480

uacuagaaaa ccacuacaac acauaugcaa gcgcaaaaug gacacacaac ggaggagaaa      540

uguucguagc auuaaaccaa aaaggaauac caguaagagg aaaaaaaaca aaaaaagaac      600

aaaaaacagc acacuuccua ccaauggcaa uaacauaagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  3747
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt13)

<400>  3747
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

uauuaccauc aguaguacua aaacuauuuc uagcagcagu acuaucagca uuaguaacag      120

gagaaagccu agaaagacua agaagaggac uagcagcagg aaccucaaac ccagacccac      180

caacaguauc aacagaucaa uuacuaccac uaggcggagg aagagauaga aaaguaagag      240

acuuacaaga agcagaccua gauuuacuaa gaguaacauu aucaucaaaa ccacaagcac      300

uagcaacacc aaacaaagaa gaacacggaa aaagaaaaaa aaaaggaaaa ggauuaggaa      360

aaaaacgaga uccaugccua agaaaauaua aagacuucug cauacaugga gaaugcaaau      420

acgucaaaga acucagagca ccaagcugca uaugucaccc uggauaccac ggagaaagau      480

gccacggacu aagucuucca guagaaaaca gauuauacac auacgaccac acaacaauac      540

uagcaguagu agcaguagua uuaagcucag uaugucuauu aguaauagua ggucuacuaa      600

uguucagaua ucaccgaaga ggaggauacg auguagaaaa ugaagaaaaa guaaaacuag      660

gaaugacaaa uagccacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  3748
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt13)

<400>  3748
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

uaacuaaacu auuaccagca uuacuauuac aacauguccu acuacaccua cuauuacuac      120

cuauugcaau accauacgcc gaaggucaaa gaaaacgaag aaauacaaua caugaguuca      180

aaaagucagc aaaaacaaca uuaaucaaaa uagacccagc acuaaaaaua aaaacaaaga      240

aaguaaauac agcagaucaa ugugcaaaca gaugcacuag aaacaaagga cuaccauuua      300

cauguaaagc auucguauuu gauaaagcaa gaaaacaaug ucuaugguuu ccauuuaaua      360

gcaugaguuc aggaguaaag aaagaguucg gacaugaauu ugaccuauau gaaaauaaag      420

acuauauaag aaauugcaua auagguaaag gaagaucaua uaaaggaaca guuuccauca      480

caaaaucagg aauaaaaugu caacccuggu caucaaugau accacacgaa cauagcuuuc      540

uaccaagcuc auacagaggu aaagaucuac aagaaaauua uuguagaaau ccgagaggug      600

aagaaggcgg accauggugu uuuacuucua auccagaagu acgauaugaa guaugugaua      660

uaccgcaaug cucagaagua gaauguauga cauguaacgg agaaucauau agagguuuga      720

uggaucauac agaaucaggc aaaauauguc aaagguggga ccaccaaacu ccacaucgac      780

auaaauuucu accagaacgu uauccagaua aaggcuuuga ugauaauuac ugucgaaacc      840

cagacggaca accaagaccu uggugcuaca cauuagaucc ccauacucga ugggaauacu      900

gugcaauaaa aacaugcgca gauaacacaa ugaaugacac agauguuccu cuagaaacua      960

cugaaugcau acaaggacaa ggagaaggau accgaggaac uguaaauaca auauggaaug     1020

gaauaccuug ucaaagaugg gauucacaau auccucauga acaugacaug accccagaaa     1080

auuuuaaaug caaagaucua agagaaaauu auugcagaaa cccagacgga ucugaaucgc     1140

caugguguuu uacaacugau ccuaacauaa gaguaggcua uugcucucag auaccgaauu     1200

gcgacaugag ccauggacaa gacuguuaua gaggaaaugg caaaaauuac augggaaauc     1260

ucagucaaac aagaucagga uuaacuuguu caauguggga caaaaauaug gaagauuuac     1320

auagacacau auucugggaa ccagacgcau caaaauuaaa ugaaaacuau ugcagaaauc     1380

cagaugacga cgcacacggg ccaugguguu auacaggaaa uccauuaaua ccaugggacu     1440

acuguccuau aagccgaugu gaaggagaua caacucccac aauuguaaac uuagaucauc     1500

caguaaucuc augugccaaa acaaaacaau uaagagucgu aaacgguaua ccuacuagga     1560

caaacauagg cuggauggug ucacuuagau auagaaauaa acacauaugc ggaggcaguc     1620

uuauaaaaga aucauggguc cucacagcaa gacaauguuu ucccagcaga gauuuaaagg     1680

acuaugaagc augguuagga auacacgaug uacacggacg aggagacgaa aaauguaaac     1740

aaguacuaaa uguuucucag cuagucuaug gaccagaagg gagcgauuua gucuuaauga     1800

aacuagcaag accggcaguc uuagacgacu ucguaucuac aauugauuua ccuaacuacg     1860

gaugcacgau accagaaaag acuagcuguu cuguuuaugg augggguuau acuggacuaa     1920

ucaacuacga cggacuauua aggguggcac auuuauauau uaugggaaac gaaaaauguu     1980

cucaacacca cagaggaaaa guaacauuaa acgaaucaga aauaugcgca ggagcagaga     2040

aaaucggauc aggcccgugu gaaggagacu auggugggcc gcuagugugc gaacaacaca     2100

aaaugcgaau gguauuaggg guaauaguac cuggacgggg augcgccaua ccaaauagac     2160

caggaauauu cguaagagua gcauauuaug ccaaauggau acauaaaaua auacuaacau     2220

auaaaguacc acaaucuuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  3749
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt13)

<400>  3749
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aagcagcugc aauaggaaua gaucuaggaa caacauacuc cuguguagga guauuccaac      120

acggaaaagu agaaauaauc gcaaaugauc aagguaacag aacaacacca ucauacguug      180

cauuuacaga cacagaaaga uuaauaggag augcagccaa aaaccaaguc gcacuaaauc      240

cacaaaacac aguauuugau gcaaaacgcu uaauaggaag aaaauuuggc gauccaguag      300

uacaaucaga caugaaacau uggccauuuc agguaauaaa cgauggagau aaaccaaaag      360

uucaaguuag uuacaaaggc gaaacuaaag cauuuuaccc ggaagagaua ucaagcaugg      420

uauuaacaaa aaugaaagaa aucgcagagg cuuauuuagg auacccagua acaaacgcag      480

uaauaacagu accagcuuac uuuaaugaua gucagagaca agcaacuaaa gaugccggag      540

uaauugccgg acuaaacgua cuaagaauaa uaaacgaacc aacugcagca gcaauagcau      600

auggauuaga uagaacaggc aaaggagaaa gaaauguauu aauauucgac cuaggaggag      660

guacauucga cgugucaaua uuaacaauug augauggaau auucgaagua aaagcaacag      720

ccggggacac acauuuaggg ggagaagauu uugacaacag acugguaaac cauuuuguag      780

aagaauuuaa aagaaaacac aagaaagaca uuucacaaaa uaaaagggca guuagaagac      840

uaagaacugc augugagagg gcaaaaagga cguuaagcag uaguacccaa gcaucacuag      900

agauagacuc auuauuugaa ggaauugauu uuuauacuuc aaucacgaga gcgagauuug      960

aagaauuaug uagugaucuc uuuagaucga cauuagaacc ugucgaaaaa gcacuaagag     1020

augcgaaacu agacaaagca caaauacaug acuuaguucu aguaggagga ucaaccagaa     1080

uaccaaaagu acaaaaacua cuacaagauu ucuucaacgg aagggacuua aauaaaucaa     1140

uaaacccaga ugaagcuguc gcuuacggug cagcugucca agcagcaaua cuaaugggag     1200

auaaaagcga gaaugugcaa gacuuauuau uauuagacgu ugcaccucua ucgcuaggac     1260

uagaaacagc aggaggagua augacagcac uuauaaaaag aaacagcaca auaccgacua     1320

aacaaacgca aauauuuaca accuauucag auaaccaacc uggcguccuu auacagguuu     1380

augaagguga aagagcaaug acaaaagaua acaaucuacu aggaagauuu gagcuaagug     1440

gaauaccacc agcaccucga ggaguaccac aaauagaagu uacauucgac auagacgcua     1500

auggcauucu aaaugugaca gcuacugaca aaaguaccgg aaaagcaaau aaaauaacua     1560

uuacaaacga uaaaggaaga cuaagcaagg aagagauaga acgcauggua caggaagcag     1620

aaaaauacaa agcggaagac gagguccagc gagaaagagu aagcgcuaaa aacgcauuag     1680

aaucauaugc auucaacaug aaaagcgcag uagaagauga aggacuaaaa gguaaaauaa     1740

gcgaagcaga uaaaaagaaa guacuagaua aaugucaaga aguuauaagu ugguuagaug     1800

caaauacuuu agcggaaaaa gaugaauuug aacauaaaag aaaagaacua gaacagguau     1860

gcaauccuau uauaucagga uuauaccaag gagcuggagg accaggacca ggaggcuucg     1920

gagcacaagg accgaaagga ggauccggau cagggccaac aauagaagaa guagauuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3750
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt13)

<400>  3750
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcaa       60

aagcugcagc aauaggaaua gaccuaggaa caacauacuc cugcguagga guauuucagc      120

augguaaagu ugaaauaaua gcuaacgacc aaggcaacag aacaaccccc ucauacgucg      180

cauucacaga uaccgaaaga uuaaucggag augcggcuaa aaaccaagug gcacucaauc      240

cacaaaacac aguauuugac gcaaaaagac ugauaggaag aaaauucggc gauccagugg      300

uucaaucaga uaugaaacau uggccauucc agguaauaaa ugauggagau aaaccaaaag      360

uacaaguauc auauaaagga gaaacaaaag cauuuuaucc agaggaaaua aguaguaugg      420

uauuaacaaa aaugaaagaa auagcugaag cauaucucgg auacccagua acaaacgccg      480

uaauaacagu uccagcauau uucaacgaca gucaaagaca agcaacaaaa gaugcaggag      540

uaauagcugg ccuaaaugua cuuagaauaa uaaaugaacc uacugcugcu gccauagcau      600

acggacuaga ucgaacaggc aaaggagaaa gaaauguuuu aauauucgac cuuggaggag      660

gaacauucga cguaagcauu uuaacaauag augauggaau auuugaaguu aaagccacug      720

caggggauac ucaccuagga ggagaagauu ucgauaacag gcuaguuaau cauuuuguag      780

aagaauuuaa aagaaaacau aagaaagaca uaagucaaaa caaaagagca guaagaagau      840

ugagaacagc augugaaaga gcuaaaagaa cgcuaagcuc aagcacacaa gcaaguuuag      900

aaauagauag uuuauuugaa ggaauagauu uuuauacuuc gauaacgaga gcaagauuug      960

aagaauuaug uucagauuua uuuagaucaa cguuagaacc aguugaaaaa gcacuaagag     1020

acgcaaaauu agauaaagcu caaauacaug accuagucuu ggucggaggc ucaacacgaa     1080

ucccuaaagu acaaaaauua cuucaagauu ucuuuaacgg uagagaucua aauaaaucaa     1140

uaaaucccga cgaagcugua gcauauggag cagcuguaca agccgcaauu cuuaugggag     1200

auaaaucaga aaauguacaa gauuugcuac uuuuagacgu ggcaccacuu agccuaggac     1260

uagaaacagc uggaggagua augaccgcau uaauaaaacg caacucgacu auaccaacaa     1320

aacaaacaca aaucuuuaca acauacagug auaaucaacc aggaguacua auacaaguau     1380

augaaggaga aagagcaaug acuaaagaca auaaucuacu aggacgguuc gaacuaagcg     1440

gcauuccacc agcaccucga ggaguaccac aaauugaagu aacauuugau auagacgcaa     1500

acgggauauu aaacguuaca gcaaccgaua aaagcacagg caaagcaaac aaaauaacaa     1560

uuacaaauga uaaaggaaga cuuucaaaag aagaaauaga gagaauggua caagaagcug     1620

agaaauacaa agccgaagac gaaguccaaa gagaaagagu uagcgcuaaa aacgcacugg     1680

aaucauaugc uuucaauaug aaaucagcag uagaggacga aggacuaaaa ggcaaaauuu     1740

cagaagcaga caaaaagaaa guacuagaua aaugucaaga aguaauuagc ugguuagaug     1800

caaauacccu ggcagagaaa gaugaauuug aacauaaaag aaaagaauua gaacaaguau     1860

gcaaucccau aauaucaggu cuguaucaag gagcaggcgg gccaggacca ggaggauuug     1920

gagcacaggg accaaaaggu ggauccggua gcggcccaac aaucgaagaa guagauuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3751
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt13)

<400>  3751
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcaa       60

cagcaaaagg aauagcaaua ggaauagacu uagggacaac uuacaguugu guuggaguau      120

uucagcacgg gaaagucgaa auaauagcaa acgaucaagg uaauaggacc accccuucgu      180

acguagcauu uacagauacu gaaagacuaa uaggugaugc agcgaaaaac caagucgcaa      240

ugaacccgca aaauacagua uuugacgcaa aacgguuaau uggaagaaag uuuaacgacc      300

caguuguaca agcagauaug aaauuauggc cauuccaagu aauaaacgaa ggaggaaaac      360

cuaaaguguu gguauccuau aaaggcgaaa acaaagcauu uuauccggaa gaaauaucau      420

caaugguacu aacaaaacuu aaagaaacgg cagaagcauu ucuaggacau ccagucacaa      480

acgcaguaau aacaguucca gcauacuuua acgauaguca aagacaagca acgaaagaug      540

caggaguuau agcaggucua aauguacuua ggauaaucaa cgaaccaacg gcagcagcaa      600

uagcauacgg acuagauaaa ggaggacaag gagaaagaca uguacuaaua uuugauuuag      660

gcggaggaac auucgacgua aguauauuaa ccauagauga uggaauauuc gaaguaaaag      720

caacagcagg ggacacacac uuaggaggcg aagacuucga uaacaggcua guaagccauu      780

uuguagaaga guucaaaaga aaacacaaga aagauauauc acaaaauaaa cgcgcaguac      840

gaagacucag aacagcuugc gaaagggcaa aaagaaccuu aagcucuagu acacaagcaa      900

accuggaaau cgauaguuua uacgaaggaa uagauuucua uacaucaauc acuagagcua      960

gauuugaaga acucugugca gaucuauuua gaggaacauu agaacccgua gaaaaagcgc     1020

uuagagacgc caaaauggac aaagcaaaaa uacaugacau aguccuagua gguggaagua     1080

cgcguauacc aaaaguacaa agauuauuac aggauuauuu caacggaaga gaucuuaaca     1140

aaaguauaaa ucccgaugaa gcaguagcau acggugcagc aguacaggca gcaauacuaa     1200

ugggagauaa aucugaaaaa guacaagacu uacuacuguu agacguagca ccacuuucac     1260

uaggacuaga aacagcugga gguguaauga cagcauuaau aaaaagaaau ucaacuauac     1320

caacuaaaca aacacaaaua uuuacaaccu auagugacaa ucaaccagga guacuaauac     1380

aaguauauga aggagaaaga gcaaugacaa aagauaacaa ucugcuagga agauuugauc     1440

uaacgggaau accaccagca ccaagaggag uaccacaaau agaaguaacg uuugacauug     1500

augcaaaugg aauacuaaac gugaccgcca cagauaaaag uacuggaaaa gucaauaaaa     1560

uaacuaucac aaacgauaaa gggagacuaa gcaaagaaga gauagaaaga augguuuuag     1620

augcagaaaa auacaaagca gaagacgagg uacaaagaga gaaaauagca gcuaaaaaug     1680

cauuagaauc auaugcauuu aauaugaaaa gcguaguauc agacgaagga uuaaaaggaa     1740

aaauaagcga aagugauaaa aacaaaauac uagacaaaug caaugaacua uuaucauggu     1800

uagaaguaaa ucagcuagca gaaaaagaug aauuugacca uaaaagaaag gaacuagaac     1860

aaauguguaa uccaauaaua acaaaauuau accaaggggg uugcacagga ccugcaugug     1920

gaacaggaua ugucccaggc agaccagcaa caggaccaac gaucgaagaa guggauuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  3752
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt13)

<400>  3752
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucag       60

cacgugggcc cgcgauaggu auagaucuag ggacaacaua cagcugcguu gggguguuuc      120

aacacggaaa aguagaaaua auagcaaaug aucaagguaa cagaaccaca ccaaguuacg      180

uugcauuuac agauacugaa agguuaauag gagacgcagc gaaaaaccaa guagccauga      240

acccaacaaa uacgaucuuu gacgcaaaac gucuuauagg acguaaauuu gaggacgcga      300

ccguccaaag cgauaugaaa cacuggccau uuagaguagu aagcgaagga ggaaaaccca      360

agguacaagu agaauacaaa ggagaaacaa aaaccuuuuu cccugaagaa auaucaucaa      420

ugguauuaac aaaaaugaaa gaaauagcag aagccuaccu ugggggaaaa guccacucag      480

caguaauaac gguaccagca uacuuuaacg auagccagag acaagccaca aaagaugcag      540

ggacaauaac aggacucaau guauuaagaa uaauuaauga gccuacagca gcagcaauag      600

cauauggauu agauaagaaa ggaugugcgg guggggaaaa gaacguauua auauuugacc      660

uagguggagg aacauucgac guaaguauac uaacaauaga agauggaauc uucgaaguga      720

aaaguacagc aggagauacu caccugggcg gagaagauuu ugauaaucga augguuucac      780

auuuagcaga agaguucaaa cgaaagcaca agaaagauau aggaccaaac aaaagagcag      840

uacgaagauu gcgaacagcg ugcgaaagag cgaaaagaac acugaguuca ucaacacaag      900

cgagcauaga aauagacuca cuuuaugaag gaguagauuu uuauacaagu auaacacgcg      960

caagauuuga agaguuaaau gcagauuuau ucagaggaac guuagaaccg guugagaaag     1020

cacuaagaga cgcaaaacuu gacaaaggcc aaauacaaga aauaguauua gucggcggau     1080

caacuagaau accaaaaaua caaaaacuac ugcaagacuu cuuuaaugga aaagaacuca     1140

acaaaagcau aaauccagac gaagcagucg cauauggugc agcaguacaa gcagcaauau     1200

uaauagggga uaaaucagaa aacgugcaag aucuacuguu acuagauguc acaccacuau     1260

cacuagguau agaaacagca ggggguguaa ugacaccucu aauaaaaaga aauacaacca     1320

uuccaacaaa acaaacacaa acauuuacaa ccuacucaga uaaucaauca agcguucuag     1380

uacaaguaua ugaaggugaa agagcaauga cgaaggauaa uaauuuauua ggaaaauucg     1440

aucucacagg uauaccacca gcgccccgag gaguaccaca aauugaagua acuuuugaca     1500

uagaugcaaa cggaaucuua aauguuacag cagcagauaa aagcaccgga aaagaaaaua     1560

aaaucacuau aacgaaugau aaaggaagau uaagcaaaga ugauauagau agaaugguac     1620

aagaagcgga aagauacaaa agugaagacg aagcaaauag agauagagug gcagccaaaa     1680

augcacuaga aagcuauaca uauaauauca aacaaacagu cgaagaugaa aaacuaagag     1740

gaaagauauc agaacaagau aaaaacaaaa uauuggacaa augucaagag guaauaaacu     1800

gguuagauag aaaucaaaug gcugaaaagg augaauauga acauaaacaa aaagaauuag     1860

aaagaguaug caauccuaua auaucaaaac uauaucaagg aggaccagga ggaggaagcg     1920

gaggaggagg aagcggcgca ucagguggac caaccauaga ggaaguagau uaaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  3753
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt13)

<400>  3753
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagug       60

uuguugguau ugauuuaggc uuccaaagcu gcuauguggc aguugcacga gcgggaggca      120

uagaaacaau agcaaaugaa uacagcgauc gaugcacccc cgcauguauc ucauucggac      180

cuaaaaacag aucaaucgga gcagcggcaa aaucacaagu aauuucaaau gcgaaaaaca      240

cuguacaggg auucaaaaga uuucauggaa gggcauucag ugacccauuu guagaagcug      300

aaaagaguaa cuuggcuuau gauauagugc aacuaccaac cggcuuaaca ggaauaaaag      360

uaacauacau ggaagaagaa agaaacuuua caacagaaca aguuaccgca auguuacuua      420

guaaauuaaa agaaacugca gaaagcgugu uaaagaaacc aguaguagau uguguuguga      480

guguacccug cuuuuacaca gaugcggaaa ggagaucugu aauggacgcu acacaaauag      540

cgggacuaaa cugcuuaaga cuaaugaaug aaacaacagc agucgcauua gccuacggca      600

uuuauaaaca agacuuaccc gcauuagaag aaaaaccaag aaacguaguu uuuguggaca      660

ugggacacuc agcauaucaa guaucagugu gugcauuuaa uagaggcaaa cuaaaaguau      720

uagcaacagc auuugacacc acacuaggag gaaggaaauu cgaugaagua cuuguaaacc      780

auuucuguga agaguucggc aagaaauaua aacuagauau aaaaucaaaa auaagagccu      840

uauuacgacu uucacaagaa ugugaaaaau uaaagaaacu gaugucagca aaugccuccg      900

aucugccacu aaguauagaa ugcuucauga augauguaga ugucucagga acgaugaacc      960

gcgguaaauu uuuagaaaug ugcaaugauc uauuggcaag gguagaacca ccgcuuagaa     1020

gcguccuaga acaaaccaaa cuaaagaaag aagauauaua ugcuguagaa auugucggag     1080

gagcaacaag aaucccagca guaaaagaga aaauaaguaa auucuuugga aaagaauuau     1140

caacaacgcu aaaugcagac gaagccguaa cacgaggaug cgcauuacag ugugccauac     1200

uaaguccagc auucaaagua agagaguuca guauaaccga cguuguacca uacccuauaa     1260

guuuaaggug gaauaguccc gcagaagaag guagcucaga uugugaagua uuuucuaaaa     1320

aucacgcagc accauuuuca aaaguauuaa cauucuacag aaaagagccu uuuacacuag     1380

aggcuuauua uucaucaccc caagaccuac cauacccuga uccagcuaua gcacaauuca     1440

gcguacaaaa agugacacca caaagcgaug ggaguagcuc aaaaguaaaa guaaaaguaa     1500

gagucaacgu acauggaaua uuuucaguaa guagugcaag ccuaguagaa guacauaaau     1560

cagaagaaaa ugaagaaccu auggaaacag aucaaaacgc gaaagaagaa gagaaaaugc     1620

aaguugauca agaagaaccc caugucgaag aacaacaaca acaaacacca gcugaaaaua     1680

aagcagaaag cgaggaaaug gaaaccagcc aagcuggauc caaagacaag aaaauggauc     1740

aaccacccca agcaaagaaa gcaaaaguaa aaacuagcac agucgacuua ccaauagaaa     1800

accaacuccu auggcagauc gacagggaaa ugcuaaaucu cuauauagaa aaugagggaa     1860

aaaugauaau gcaggacaaa cuagaaaaag agaggaacga cgcuaaaaac gcaguagaag     1920

aauacguaua cgaaaugaga gauaaacuau caggggaaua ugaaaaauuu guaucugaag     1980

augauagaaa caguuuuaca uuaaaauugg aagauacuga aaacugguua uacgaagaug     2040

gcgaagacca accaaaacaa guauacgucg acaaacuagc ugaacuaaag aaucuagguc     2100

aaccaauaaa aauaagauuc caagaaucag aagaaagacc aaaauuauuc gaagaacuag     2160

gaaaacaaau acaacaauau augaaaauaa ucucaucauu uaaaaauaaa gaagaccaau     2220

acgaccaucu agaugcagca gauaugacaa aaguagaaaa aucuacuaac gaagcaaugg     2280

aauggaugaa uaauaaauua aaccuccaaa auaaacaauc acugacgaug gaucccguug     2340

uuaaaagcaa agaaauagag gcaaaaauaa aagaacuaac aagcacgugu agucccauaa     2400

uaucaaaacc aaaaccaaaa guagaacccc caaaagaaga acagaaaaau gccgaacaaa     2460

augguccagu agauggacaa ggagacaauc caggcccaca agcagcagaa caaggaacag     2520

auacagccgu gccaucagau agugacaaga aauuaccaga aauggauauu gauuaaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  3754
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt13)

<400>  3754
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

uuguuggcau agaucucgga uuccuaaacu gcuauauagc cguagcuaga agcgguggaa      120

uagaaacaau agcgaacgaa uacucggacc gcugcacacc agcuuguauc agcuuaggau      180

cccgcaccag agcaauaggc aaugcagcga aaagccaaau agugacaaac guacgaaaua      240

cuauacaugg auuuaaaaaa cuacacggaa ggaguuucga ugacccuaua guacaaacgg      300

aaagaauacg acucccauau gaacuacaaa agaugccgaa uggaagugca ggaguaaaag      360

uaagauaccu cgaagaagaa agacccuuug caauugaaca aguaacugga auguuacuag      420

caaaauuaaa agaaacaucg gaaaacgcau uaaaaaaacc gguugccgac ugcguaauau      480

ccaucccaag uuuuuuuacg gaugcagaaa gaagaagugu aauggcggca gcacaaguag      540

caggauuaaa uugccuaagg cucaugaacg aaacgacagc aguagcuuua gcauacggaa      600

uuuauaaaca agauuugcca ccauuagaug agaaacccag aaauguagua uucauagaca      660

ugggacacuc ugccuaucaa guacucguuu gugcauucaa uaaaggcaaa uuaaaaguuu      720

uagccacaac auucgauccc uaccucggcg gaaggaauuu cgacgaagca uuaguagauu      780

auuuuugcga ugaauucaaa acaaaauaca aaauaaaugu gaaagaaaac uccagagcau      840

uacucagacu auaccaagaa ugugaaaaac uaaaaaaacu aaugagcgca aaugcaagcg      900

accucccccu aaacauagaa ugcuuuauga augacuugga cguaucuuca aaaaugaaca      960

gagcccaauu cgagcaauua ugcgcgucau uacuagcccg aguagaaccu ccacuuaaag     1020

caguaaugga acaagcaaac uuacaacgag aagauauauc aucuauagag auuguaggag     1080

gagcaacaag aauccccgca guaaaagaac agaucacuaa guuuuuuuua aaagacauuu     1140

cuacaacacu caaugccgau gaagccguug cacgaggaug ugcauuacaa ugcgccauau     1200

uauccccagc auuuaaggua agagaauuca gcauuacaga ccugguucca uauucaauaa     1260

cauuaagaug gaaaacaagu uuugaagacg gaucagguga augcgaagua uucugcaaaa     1320

accauccagc accauucucu aaaguaauua cauuccauaa aaaagaacca uuugaacuag     1380

aagcuuuuua uacuaaccua cacgaaguac cauacccaga ugcaaggauc gguucauuua     1440

caauacaaaa cguguucccg caaagcgacg gagacucuag uaaagugaaa guuaaaguaa     1500

gagucaauau acauggaaua uuuucagucg ccucagccuc agugauagaa aaacagaacu     1560

uagaaggaga ccauagugac gcuccuaugg aaacugaaac auccuucaaa aaugaaaaua     1620

aagacaauau ggauaaaaug caaguagacc aggaagaagg acaucagaaa ugccaugccg     1680

aacauacucc ugaggaagaa auagaucaua caggagcaaa aacaaaaucg gcaguaucag     1740

auaaacaaga cagauuaaau caaacucuaa aaaaagggaa aguuaaauca auagacuuac     1800

caauacaauc gagcuuaugc agacaguuag gacaagaccu acuuaacuca uauauugaaa     1860

augaaggcaa aaugauuaug caagacaaau uagaaaagga gaggaacgau gccaaaaacg     1920

cagucgaaga auacguauau gacuucagag auagacuagg aacuguauau gaaaaauuua     1980

uuaccccaga agacuuaucg aaacuaagcg ccguucuaga agauacagaa aacuggcugu     2040

augaggaugg agaagaucaa cccaaacaag uauacguuga caaacuacaa gaauugaaaa     2100

aauacggaca accaauccaa augaaauaca uggaacacga agaaagacca aaagcauuaa     2160

augaucucgg aaaaaaaauc caauuaguaa ugaaaguaau agaagccuau cguaauaaag     2220

augaaagaua cgaucaucua gacccuacag aaauggaaaa aguagaaaaa uguauaucag     2280

augcaaugag uugguuaaau ucaaaaauga acgcacaaaa uaaacuaagu uuaacgcaag     2340

acccuguagu aaaagucucu gaaaucguag caaaaagcaa agaacuggac aacuucugca     2400

accccauaau auacaaaccc aaaccuaaag cagaggugcc agaagacaaa cccaaagcaa     2460

auucugaaca uaacggucca auggacggac aaagcggaac agaaacaaaa ucagacucaa     2520

caaaagauag uucacaacau acaaagucau cuggcgaaau ggaaguugac uaaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  3755
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt13)

<400>  3755
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

uaucuuuagu agcggcaaug cuauuacuac uaagcgcagc aagggcagag gaagaagaua      120

aaaaagaaga cgucggaaca guagucggua uagaccuagg aaccacauau ucaugcgucg      180

gaguuuuuaa aaacggaaga guugaaauca uagcaaacga ucaaggaaac agaaucacac      240

caucauacgu agcguucaca ccugaaggag aacgacucau aggagaugca gcaaaaaauc      300

aauuaacauc uaacccugaa aacacagucu uugacgcaaa aagauugaua ggaagaaccu      360

ggaacgaccc uucaguucaa caagacauaa aauuucuacc auuuaaagua guagaaaaaa      420

aaacaaaacc auauauacaa guugauauug gaggcgguca aacaaaaaca uucgcaccag      480

aagaaauauc cgcaauggua cuuacaaaaa ugaaagaaac agcugaagca uaccuaggaa      540

aaaaaguaac acaugccgua guaacaguac cagcauauuu uaaugacgcc caaagacaag      600

caacaaagga ugcaggaaca auagcugguc uaaacgucau gagaauaaua aacgaaccaa      660

cagcagcagc uaucgcauac ggacuagaua aaagagaagg agaaaaaaau auacuaguau      720

uugaucuagg aggaggaaca uucgauguaa gcuuauuaac aauagacaac ggagucuuug      780

aaguaguagc uacaaacggu gacacacauu uaggaggaga agacuuugau caaagaguua      840

uggaacacuu uauaaaacua uauaaaaaaa aaaccgggaa agacguaagg aaagauaaca      900

gggccguaca gaaacucaga agagaagucg aaaaagcaaa acgagcauua ucaucacaac      960

accaagcaag aauagaaaua gaaaguuucu augaaggaga agauuuuagc gaaacucuaa     1020

cgcgagcaaa auuugaagag cugaacaugg auuuauuuag aaguaccaug aaaccaguac     1080

aaaaaguacu cgaagacagu gauuuaaaaa aaagugacau agacgaaaua guccuaguag     1140

gagguucaac ccgaaucccc aaaauacaac aacucgucaa agaauuuuuc aacggaaaag     1200

aaccgagccg aggaauaaac ccugacgaag caguagcaua uggcgcagca guucaagcag     1260

gcguauuaag cggagaucaa gauacaggag auuuaguacu acuagacgua uguccacuaa     1320

cucuaggaau agaaacaguc ggaggaguaa ugaccaaauu aauaccuaga aacacaguag     1380

uaccgacaaa aaaaucacaa auuuucucca cagcaagcga caaucaacca acaguaacca     1440

uaaaaguaua cgaaggcgaa agaccauuaa caaaagauaa ccauuuauua ggaacauuug     1500

auuuaacagg uaucccaccu gccccacgag gagucccaca aauagaaguu acauuugaaa     1560

uagauguaaa ugguauccuc agagucacag cggaagauaa aggcacugga aauaagaaua     1620

aaauuacuau aacaaacgac caaaauagau uaacucccga agaaauagaa agaaugguaa     1680

augaugcgga aaaauucgcc gaagaggaca aaaaacuaaa agagagaaua gauaccagaa     1740

acgaguuaga aucauacgca uacucccuua agaaucaaau uggagauaaa gaaaaauuag     1800

gcggcaaauu gagcucagaa gacaaagaaa ccauggaaaa agcaguagaa gaaaaaauag     1860

aauggcuuga aagccaccag gaugcagaua uagaagauuu caaagcaaaa aaaaaagagc     1920

uagaggaaau cguacaacca auaauuucaa aacuauacgg aagugcaggg ccaccaccaa     1980

caggagaaga agacaccgca gaaaaagaug aacuuuaagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  3756
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt13)

<400>  3756
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

caccacguga acuugcaguc gguauagauc uaggaacaac auauuccugu guaggaguau      120

uucaacaagg gagaguagaa auauuagcaa acgaucaagg caauagaaca acaccaucau      180

auguagcauu uacugacaca gaaagauugg uaggagaugc agccaaaagu caagcagcau      240

uaaauccaca uaacacagug uucgacgcga aaagacuaau ugguagaaaa uuugcggaua      300

caacagucca aagugacaug aagcauuggc cauuuagggu agugucugaa gguggaaaac      360

caaaaguaag aguaugcuau agaggugaag auaaaacauu uuauccagaa gaaauuucau      420

caaugguauu aagcaaaaug aaagagacag cagaagcaua ccuuggacaa ccaguaaaac      480

augcuguaau aacaguuccc gcauacuuca augauagcca aagacaagca acaaaagaug      540

cuggagcaau agcuggauua aacgugcuaa gaauuauaaa ugaaccaacc gccgcggcaa      600

uugcauaugg auuagauaga agaggagcag gagaaagaaa cguauuaaua uucgaucuag      660

gaggaggaac auuugacgua ucagucuuau caauagacgc aggcguauuc gaaguaaaag      720

caacagcugg ugauacucac uuaggaggag aagauuucga uaacagauua guuaaucacu      780

ucauggaaga auuucgacga aaacauggca aagaucuauc cggcaauaaa agagcauuaa      840

gaagacuacg aacagcgugu gaaagagcaa aaagaacauu auccucaucu acccaagcua      900

cauuagaaau agauagccua uucgaagggg uagauuuuua cacuuccaua acaagagcuc      960

gcuucgagga acuaugcuca gauuuauuua gaucuacuuu agaaccugua gaaaaagccu     1020

uacgugacgc aaaauuagau aaagcacaaa uacaugacgu cguauuagua gguggaagua     1080

cccgaauacc aaaaguacaa aaacuauuac aagauuucuu uaacggaaaa gaacuaaaca     1140

aaucaauuaa uccagaugaa gcaguugcuu acggcgcagc aguacaggca gcaguauuaa     1200

ugggagauaa augugaaaaa guacaagauu uguuacuucu agacguggca ccccuaagcc     1260

uaggauuaga aacagcagga ggaguaauga ccacauuaau acaaagaaau gcaacaauac     1320

cuacuaaaca aacacaaaca uuuacaacau auagugacaa ucaaccuggg guauucauac     1380

aaguauauga aggugaaaga gcaaugacaa aagauaauaa uuuacuaggu agauuugaau     1440

uaucagggau uccaccagca ccacgaggag uaccgcaaau agaggugacu uuugacauag     1500

acgcaaaugg caucuuaagc guaacagcaa cagauagaag cacaggaaaa gcaaacaaaa     1560

uaacaauaac aaaugacaaa ggaagguuaa gcaaagagga ggucgaaagg augguacaug     1620

aagcagagca auauaaggcc gaagaugaag cccaaagaga cagaguagca gcuaaaaauu     1680

cacuagaagc acauguguuu cacguaaaag ggagcuuaca agaagagagu uuaagagaua     1740

aaauaccaga agaagauaga cgaaaaaugc aagauaaaug cagagaagua uuagcauggc     1800

uagaacauaa ucaacuggca gaaaaagaag aauaugaaca ucaaaaacga gaauuagaac     1860

aaauaugcag accaauauuc ucaaggcuau auggcggacc aggaguacca ggaggaaguu     1920

cuuguggaac ucaagcuaga caaggagacc cuucuacagg accaauaauu gaagaaguag     1980

auuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  3757
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt13)

<400>  3757
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

cacccagaga auuagccgua ggaauagacc uaggaacuac auauagcugu gucggaguau      120

uucaacaagg aagaguugaa auauuagcaa augaccaagg aaauagaaca acaccuucau      180

auguagcauu cacagacaca gaaagguuag uaggagaugc cgcgaaaagc caagcagcau      240

uaaacccaca caauacagua uucgaugcaa aaagacucau cggaagaaaa uuugcagaua      300

caacaguaca aucagauaug aaacauuggc cauuucaagu agucucagaa ggcggaaaac      360

caaaaguaag aguauguuac agaggagaag auaaaacauu uuauccagaa gaaauaucaa      420

guaugguauu aucaaagaug aaagaaacag cagaagcaua ucuaggccaa ccaguaaaac      480

augcaguaau aacaguacca acuuauuucu caaauucaca aagacaagca acaaaagaug      540

cuggagcaau ugcaggucua aaaguauuac caaucauaaa ugaagcuaca gcugcagcaa      600

uagcauaugg ccuagauaga agaggagcag gaaaaagaaa uguauuaaua uuugauuuag      660

gaggaggaac cuuugacgua ucaguauuau caauagaugc aggaguauuu gaaguaaaag      720

caacagccgg agauacacau cuaggaggag aagauuucga caacagauua guuaaucacu      780

ucauggaaga auuuagaaga aaacacggaa aagacuuauc agguaauaaa agagcacuua      840

gaagauuaag aacagcaugu gaaagagcca aaagaacacc aucaagcuca acacaagcga      900

cauuagaaau cgauucacua uucgaaggag uagauuuuua uaaaucaaua acuagagccc      960

gauuugaaga auuauguuca gacuuauuuc gaagcacacu agaaccagua gaaaaagcac     1020

uaagagaugc aaaacuagac aaagcacaaa uacacgacuu cguauuagga ggaggacuac     1080

acagucaucc acaaggagcu gaaguagcug caggauuauu acaaagacaa ggagcagaac     1140

aagaacacca accuuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  3758
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt13)

<400>  3758
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucaa       60

aagguccugc uguaggaauu gacuuaggaa cgacauauuc guguguuggu gucuuccaac      120

augggaaagu agaaauuaua gcaaacgauc aaggaaaccg aacaacacca ucauacguag      180

cuuuuacaga uacagaaaga uuaaucggag acgcggcuaa aaaucaagua gcaaugaauc      240

caacaaacac agucuuugac gcaaaacgac uaauaggaag aagauuugau gaugcaguag      300

uucaaagcga uaugaaacac uggccauuua ugguaguaaa ugacgcagga aggccaaaag      360

uacaaguaga auacaaagga gaaacaaaga gcuucuaucc ggaagaagua ucaagcaugg      420

uauuaacaaa aaugaaagag auagcagagg cauacuuagg aaaaacagua acaaacgcag      480

uagucacagu uccagcauau uucaacgaua gccaaagaca agcaacaaaa gacgcaggua      540

caauagcagg auuaaaugua cuccggauaa uaaacgaacc aacagcugcu gcaaucgcgu      600

auggacuaga uaagaaagua ggcgcagaaa gaaauguauu aaucuucgac uuaggaggag      660

gaacauucga uguaucuauu cuaacaauag aagacggcau auucgaagua aaaagcacag      720

ccggcgacac acacuuagga ggagaagauu ucgauaaccg aaugguaaac cauuucauag      780

ccgaguucaa aaggaaacac aagaaagaca uaagugaaaa uaaaagagca guacgccgau      840

uaagaaccgc augugaaaga gcaaaaagaa cucuaaguuc aagcacacaa gcgaguauag      900

aaauagacag uuuauaugaa gguauagauu uuuauacauc aauaacaaga gcaagauucg      960

aagaacuuaa cgcagaccua uuuagaggaa cacuagaccc aguagaaaaa gcacuaagag     1020

augcaaaauu agacaaaagc caaauacaug auauaguauu ggucggagga ucgacuagaa     1080

ucccaaaaau acaaaaacua uuacaagacu ucuuuaacgg aaaagaacuc aauaaaucga     1140

uuaauccaga ugaagcaguc gcauauggag cugcgguaca agccgcgaua uuaagcggag     1200

acaaauccga aaacguccaa gaucuauuac ucuuagacgu aacaccucug ucgcuaggaa     1260

uugaaacagc cgguggggua augacaguac uaauaaaaag aaacaccaca auaccaacua     1320

aacaaacaca aacauuuacu acauacucag auaaucaacc aggaguccua auucaaguuu     1380

acgaagggga acgugcaaug acaaaagaca auaauuuacu cggaaaauuu gaacuaacag     1440

gaauaccacc agcaccaaga ggaguaccac aaauagaagu aacauuugau auagaugcaa     1500

auggaauacu aaacguaagu gcgguagaua aaagcacagg uaaagaaaac aaaauaacaa     1560

uaacuaacga caaaggcaga uuaucaaaag aagauauaga aagaauggug caagaagcag     1620

aaaaauauaa agcagaagac gaaaaacaaa gagauaaagu aaguaguaaa aauucauuag     1680

aaucauacgc auuuaauaug aaagcaacgg uagaagauga aaaauugcaa ggaaaaauaa     1740

acgaugaaga uaagcagaaa auuuuagaca aauguaacga aauuauaaau ugguuagaua     1800

aaaaucaaac agcagagaaa gaggaauuug aacaucaaca aaaagaauug gaaaaggucu     1860

gcaauccuau aauaaccaaa uuauaccaau cugcgggagg aaugccaggc ggaaugccag     1920

gaggauuccc agguggagga gcuccaccaa gcggaggagc aagcagugga ccaacaauag     1980

aagaagucga uuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  3759
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt13)

<400>  3759
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauca       60

gugcaagcag agcugccgca gcaagauuag uaggagcggc agcaagcaga ggaccaaccg      120

cugcuagaca ucaagauagu uggaauggau uaucacacga agcauuuaga cucguaagua      180

gacgagacua ugcaagcgag gcaauaaaag gcgcaguagu agggaucgau uuagggacga      240

caaacucaug cguagcaguc auggaaggaa aacaagcaaa aguacuagaa aaugcagaag      300

gagcgagaac aacaccauca guaguagcgu uuacugcaga uggagaaagg cuaguaggca      360

ugcccgcuaa aagacaagca guaacaaauc caaauaauac auuuuaugca acaaaaagau      420

uaauaggaag aagauaugau gacccagagg uacagaaaga caucaaaaau guaccuuuua      480

aaauaguaag agcaaguaac ggagacgcau ggguagaagc acaugguaaa cuauauaguc      540

cgucgcaaau aggagcauuu guucuuauga aaaugaaaga aacggcagaa aauuaucuag      600

ggcauacagc caagaacgca guaauaacag uacccgcaua uuucaacgau ucacagcguc      660

aagcaacgaa agaugcggga caaauuagug ggcugaaugu auuaagagua auaaacgaac      720

ccacagcugc agcccuagcg uauggacucg auaaaucaga agacaaagua aucgcaguau      780

augauuuagg ugggggaacc uuugacauuu caauauuaga aauacaaaaa ggcguauuug      840

aaguaaaaag uacaaaugga gauacauucu uaggaggaga agacuucgau caagcucuau      900

uacgacauau agugaaagag uucaaaagag aaacaggagu ugacuuaaca aaagauaaca      960

uggcacuaca aagaguaaga gaagcagcug aaaaagcgaa augcgaacua aguaguagug     1020

uacaaacaga cauaaacuua ccauacuuaa caauggacuc aucagggcca aaacaucuua     1080

acaugaaacu gacuagagca caauucgaag gaauagucac cgaucuaaua cguaggacca     1140

uugcaccaug ccagaaagca augcaggacg cagaaguauc gaaaagcgau auaggagaag     1200

uaauauuagu ugggggaaug acaagaaugc cuaaaguaca acaaacagua caagauuuau     1260

uuggaagggc accaucaaaa gcaguaaacc cagacgaagc aguggcgaua ggagccgcaa     1320

uacaaggagg aguacuagca ggagacguaa cugauguuuu auuacuagau guaaccccac     1380

uaaguuuggg aauagaaaca uuaggaggag uauuuacaaa acuaauaaau agaaauacca     1440

caauaccuac aaagaaaucu caaguauuuu caacagcagc agacggccaa acacaagugg     1500

aaauaaaagu augucaaggc gaaagagaaa uggcaggaga caauaaacug uuaggacaau     1560

uuacuuuaau agguauacca ccagcaccaa ggggaguacc ucaaauugaa guaacauucg     1620

acauagacgc aaauggaaua guccauguau cagcgaaaga uaagggcaca gggagggaac     1680

aacaaauagu aauacaaagu agcggaggac ugaguaaaga cgauauagaa aauaugguca     1740

aaaaugcuga aaaauaugcu gaagaggaua ggaggaagaa agaaagggua gaagcgguaa     1800

auauggcaga aggaauaaua caugacacag aaacaaaaau ggaagaauuu aaagaucaau     1860

uaccagcgga ugaauguaau aaacucaaag aagaaauaag uaaaaugaga gaguuacuug     1920

caagaaaaga uucagaaacg ggagaaaaua uacgacaagc agcaaguuca cuacaacaag     1980

cuagucuaaa auuauucgaa auggccuaua agaaaauggc aucggaacga gaaggaucag     2040

gaucaucugg uacaggggaa caaaaagaag aucaaaaaga agaaaaacaa uaaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  3760
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt13)

<400>  3760
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcug       60

auaaagaagc cggaggaucu gauggcccua gagaaaccgc accaacuuca gcauauagca      120

gccccgccag aucauuagga gauacaggca uaacucccuu aucaccaucc cauauaguaa      180

acgauacaga uaguaauguc uccgaacaac aaucauuuuu gguuguugua gcagucgauu      240

ucgguacaac aagcuccgga uacgcauauu ccuucacaaa agaaccggaa uguauacaug      300

uuaugagaag augggaaggc ggcgacccag gaguuaguaa ccaaaagacu ccaacuacaa      360

uccucuuaac accggaaagg aaauuccauu cauucggaua ugccgcacgc gauuuuuacc      420

acgauuuaga cccaaacgaa gcgaaacaau gguuauaucu agaaaaauuu aaaaugaaac      480

uacauaccac aggagaccuu acuauggaua cagaccuaac agcugcaaau ggaaagaaag      540

uaaaagcauu agaaaucuuu gcauacgcgu uacaauacuu uaaagaacaa gccuuaaaag      600

aauuaagcga ccaagcugga ucagaauuug aaaauuccga cguacgaugg gucauaacgg      660

uaccugcaau auggaaacaa ccagcaaaac aauucaugag acaagccgcc uaucaagcug      720

gacuagcguc accagaaaac agcgaacaac uaauaauagc acuagaacca gaagcagcau      780

caaucuauug uagaaaacua agauuacauc aaaugauaga acuaucauca aaagcugcag      840

uaaauggaua uucaggaagu gacaccguag gugcaggauu uacucaagcc aaagaacaca      900

uaagaagaaa uagacaaucu agaaccuuuc uagucgaaaa uguaauuggc gaaauauggu      960

cugaauuaga agaaggagac aaauaugucg uaguugacuc cgguggagga acaguggauc     1020

ucaccgucca ucaaauacga cuaccagaag gacaucuuaa agaacucuac aaagcuacag     1080

gaggaccaua uggcucauua ggcguagauu augaauuuga aaaacugcua uacaaaaucu     1140

ucggagaaga cuuuauagaa caauuuaaaa ucaaaagacc agcagcaugg guagauuuaa     1200

ugauagcauu cgaaucaaga aaaagagcug cagcaccaga ucgaacuaau ccguuaaaua     1260

uaacguuacc auucucauuc auugacuacu auaaaaaguu uagaggucau aguguugaac     1320

augcacuaag aaaaucgaau guagauuuug uaaaaugguc aagucaaggc auguuaagaa     1380

ugucaccaga ugccaugaau gcauuauuua aaccaacuau agauucaaua auagaacauu     1440

uaagagacuu auuccaaaaa ccagaaguau cuacaguuaa auucuuauuc cuaguagggg     1500

gauuugcaga agcuccacuu cuacaacaag cagugcaagc agcauucggc gaccaauguc     1560

gaauaauaau accucaagac guaggccuca caauacuaaa aggagcggua uuauuuggau     1620

uagauccugc agucauaaaa guaagaagau caccucuaac auacggugua ggaguacuaa     1680

acagguacgu agaaggaaaa cacccaccug aaaaacuuuu agucaaagac ggaacuagau     1740

ggugcacaga uguauuugau aaauucauau cagcagauca aucaguagca uuaggagaac     1800

ugguaaaacg aucauacacu ccugcuaaac ccagccaauu aguaaucgua auaaauauau     1860

auucaaguga acaugauaau gucucauuua uaacagaucc aggaguaaag aaaugcggaa     1920

cauugagauu ggaccucaca ggaacaucag gaacagcugu accagcaaga cgagaaauuc     1980

aaacacuaau gcaauuugga gauaccgaaa uaaaagcaac ugcaauagau auagccacca     2040

gcaaaagugu aaaaguggga aucgauuucu uaaauuauua aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  3761
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt13)

<400>  3761
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcuag       60

caguaccuga aaugggauua caaggucuau auauagguag cucgccagaa cgaucaccag      120

uaccaagucc gccgggauca ccucgcacac aagaaagcug uggaauugca ccacuaaccc      180

cuucucaauc accaaagcca gaaguuagag caccccaaca ggcuucauuu ucuguaguag      240

uagcaauaga cuuuggcacc acauccucag gcuaugccuu cagcuuugca ucagacccag      300

aagcgauaca uaugaugagg aaaugggaag gaggagaucc agggguagca caucagaaaa      360

caccuacuug cuuauuacua acaccagaag gcgcauuuca uaguuuugga uauacagcaa      420

gagacuauua ucaugaucug gauccugaag aagcgcguga uugguuauau uuugaaaaau      480

uuaaaaugaa aauccauuca gcaacagauc uaacuuuaaa aacacaauua gaagcuguca      540

auggcaaaac aaugccagca uuagaaguau uugcccaugc acuaagauuu uuccgagaac      600

augcacuaca agaacuuaga gaacaauccc caaguuuacc ugagaaagau acaguaagau      660

ggguauuaac agugccggca auauggaaac aaccugcuaa acaauucaug agggaagccg      720

ccuauuuagc aggauugguu ucacgagaaa acgcagaaca acuauugaua gcuuuagagc      780

cagaggcggc aaguguauau uguagaaaac uaagauuaca ucaacuacua gauuuaucag      840

gcagagcucc aggaggaggu agauuaggag aaagacgauc cauugauucu aguuuuagac      900

aagcuagaga acaacuaaga agaagcagac auucaagaac auuccuugua gaaaguggag      960

uaggagaauu augggcagaa augcaagcag gagauagaua uguaguugca gacuguggag     1020

gaggaacugu agaccucaca guucaucaac uagaacaacc acaugguacc cuaaaagaau     1080

uauauaaagc gaguggcggc ccauacggag caguaggcgu agauuuagca uuugaacaau     1140

uacucugucg aauauuugga gaagauuuca uagcuacuuu uaaaagacaa agaccagcug     1200

cauggguaga ucuaacuaua gcuuucgaag caagaaaaag aacagccgga ccucauagag     1260

caggagcauu aaauauaucu cuaccauuua guuuuauaga uuuuuacaga aaacaacggg     1320

gacauaacgu agaaacggca uuacgaagau caagugucaa cuucguaaaa uggucaucac     1380

aagguauguu aagaaugucc ugugaagcaa ugaaugaacu auuucaaccc acuguaagcg     1440

gaauaauaca acacauagaa gcauuauuag caagacccga aguucaagga guaaaauuac     1500

uauuucuagu aggaggguuu gccgaaucgg caguucuaca acaugcagua caagcugcgu     1560

uaggcgcacg aggauuacga guaguaguac cccacgaugu ugggcuuaca auucugaaag     1620

gagcuguauu auuuggacag gcaccaggag uagucagagu uagaagaagc ccacuaacau     1680

augggguagg aguacuuaac agauuuguac caggcaggca uccuccagaa aaauuauuag     1740

uacgagacgg aagacguugg uguacagaug uauucgaaag auucguugca gcugaacaaa     1800

gcguugcauu aggagaagaa guaagacgau cauauugccc agcuagacca ggucaaagaa     1860

gaguucuaau aaacuuauau uguugcgccg cagaagaugc aagguuuauu acugauccug     1920

gaguucgaaa auguggugca cuuagccuag aacuagaacc ggccgauugu ggacaagaua     1980

cagccggagc accaccaggu agaagagaaa uaagagcugc uaugcaauuc ggagacaccg     2040

aaauaaaagu cacagcagua gaugucagca caaauagauc agugcgagcu aguauagacu     2100

uucuaucaaa uugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  3762
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt13)

<400>  3762
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

gagaaaugac cauauuagga agcgccguau uaacauuauu acuagcggga uauuuagcac      120

aacaauaucu accccuaccc acaccaaaag uaaucggaau agacuuagga acaacauauu      180

guaguguagg aguuuucuuc ccaggaaccg gaaaagucaa aguaauacca gacgaaaacg      240

gacacauauc aauuccauca augguaucau uuacugauaa cgacguauau guaggauacg      300

aaucaguaga auuagccgau agcaauccac aaaacacuau auaugacgca aaaagauuca      360

uaggcaaaau auuuacagca gaagaacuug aagcugaaau aggaagauau cccuuuaaag      420

uacuaaauaa aaacggaaug guagaauucu caguuacauc aaaugaaaca auaacaguca      480

guccagaaua cguagguagc agauuacuac uaaaacuaaa agaaauggca gaagcauacu      540

uaggaaugcc aguagcaaau gccguaauau cuguaccagc agaauucgau uuaaaacaac      600

gaaauucaac aauagaagca gcuaaucuag caggacuaaa aauauuaaga guuauaaacg      660

aacccacagc agcagcaaug gccuauggau uacacaaagc ugacguauuu cauguacuag      720

uaauagaucu agguggaggu acauuagacg uaagcuuacu aaauaaacaa ggaggcaugu      780

uucuuacacg agcaauguca ggcaacaaca aauuaggagg ucaagacuuu aaccaaagac      840

uacuacaaua ucucuacaaa caaauuuacc aaacuuaugg auuuguuccu ucaagaaaag      900

aagaaauaca ucgauuacga caagcaguag agaugguaaa acuaaauuua acacuacauc      960

agagugcaca acuuuccguc uuauuaacag uugaagaaca agaucgaaaa gaaccacaca     1020

guucagacac cgaacuucca aaagauaaau uaagcucagc agaugaccau agaguuaaca     1080

gcggcuuugg aagaggauua ucagacaaaa aaagcggaga aagccaagug cuguuugaaa     1140

ccgaaauaag cagaaaauua uucgauacac uuaacgaaga ccuauuccaa aaaauauuag     1200

uaccaaucca acaaguacua aaagaagguc aucuagaaaa aacagaaaua gaugagguag     1260

uauuaguagg aggaucaaca cguauaccca gaauaagaca aguaauacag gaauuuuucg     1320

gaaaagaucc aaauacauca guagacccag auuuagcggu uguuacagga gucgcaauac     1380

aagcaggaau agauggcgga agcuggccau uacaaguauc cgcacuagag aucccaaaca     1440

aacaucuaca aaaaaccaau uucaauuaag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3763
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt13)

<400>  3763
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

caauaggagu acauuuagga uguacaagug cauguguagc aguauauaaa gauggaagag      120

caggaguagu agccaaugau gcaggggaua gaguaacacc agcgguagua gcuuauucag      180

aaaaugaaga aauaguagga uuagcugcaa aacaaucaag aauaagaaau auuaguaaca      240

ccguaaugaa agugaaacaa auacuaggaa gaucuucauc agauccccaa gcacaaaaau      300

auauagcaga aucaaaaugu cuaguaauag aaaaaaaugg caaacuaaga uaugaaauag      360

auacaggcga agaaacaaaa uuuguaaacc cugaagaugu cgcuagacua auauucucaa      420

aaaugaaaga aacagcacau ucaguacuag gaucagaugc aaaugacgua guaauaaccg      480

uaccauuuga uuuuggagaa aaacaaaaaa augcauuagg agaagcagca agagcagcag      540

gauuuaacgu guuacgacuu auacaugaac ccucagcagc auuauuagcc uauggaauag      600

gucaagacuc accaacaggc aaaucaaaua uauuaguauu uaaauuagga ggaacuaguc      660

uaucacucuc aguaauggaa guaaauucag gaauauacag aguuuuauca acuaauacag      720

augauaauau uggaggagca cauuuuacag aaacauuagc ucaauaccuu gcaagugaau      780

uucaaagaag uuuuaaacac gaugucagag gaaaugcaag agcaaugaug aaacuaacga      840

auucagcaga aguagcaaaa cauucauuau caacauuagg gucugccaau uguuuccuag      900

auagucuuua ugaagggcaa gacuuugacu guaauguaag ucgagcaaga uuugaacuac      960

uguguucacc ccuguuuaac aagugcauag aagcaauaag gggauuacua gaucaaaaug     1020

gcuucaccgc agaugacauc aauaaaguag uacuaugugg aggaagcuca agaauaccaa     1080

aacuccaaca auuaauaaaa gauuuauuuc ccgcuguaga acuacuaaau aguauacccc     1140

cagaugaagu aauaccaaua ggugccgcaa uagaagcagg cauauuaaua ggcaaagaga     1200

aucuacuagu ggaagacagu cuaaugauag aauguagugc aagagacaua uuaguaaaag     1260

ggguagauga aaguggagca agcagauuua caguauuauu ccccagcgga acaccucuac     1320

cagcaagaag acaacauacu cuacaagcgc cagguucaau aucaucaguu ugccuagaac     1380

uauacgaauc agacgguaaa aacucagcaa aagaagaaac aaaauucgcu caaguaguac     1440

uacaagauuu ggacaaaaaa gagaauggac uaagagauau ucuagccgua uugacuauga     1500

aaagagaugg aucacuacac guaacaugua cagaccaaga aacaggaaaa ugugaagcaa     1560

ucucuauaga aauagccuca uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  3764
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt13)

<400>  3764
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagug       60

uuguggggcu agacguaggg agccaaaguu gcuauauagc aguagccaga gccggaggaa      120

uagaaacgau agcaaaugaa uucucagaua gaugcacccc aaguguaaua ucauucggau      180

caaaaaacag gacgauagga guggcagcca aaaaucaaca gauaacgcac gcaaauaaca      240

cagucagcaa cuuuaaaaga uuucacggaa gagcauuuaa cgacccauuu auacaaaaag      300

aaaaagagaa ucuaaguuac gacuuagucc cccuaaaaaa uggaggagug ggaauaaaag      360

uaauguauau gggcgaagaa caccuuuuuu caguugaaca aauaacugcg augcuauuaa      420

caaaacuaaa agaaacagca gaaaacucau uaaaaaaacc aguaacagac ugcguaauau      480

caguaccauc auucuuuaca gacgcugaac gacgaagugu ucuagacgca gcacagauag      540

uagguuugaa uugucuaaga cugaugaacg acaugacagc aguagcguua aacuacggaa      600

uauacaaaca ggaccuacca agcuuggacg agaaaccuag aauaguagua uucguagaca      660

uggggcacuc ugcauuccaa guuagugcau gcgcauucaa uaaagguaaa cucaaaguau      720

uaggaacagc auuugaccca uucuuaggag gcaaaaacuu ugacgaaaaa cuuguugaac      780

auuucugcgc ggaauucaaa acaaaauaua aauuggacgc caaaagcaaa auaagagccc      840

uuuuacgacu auaccaagag ugcgaaaaac uaaaaaaacu aaugaguagu aauucaacug      900

accuaccacu caauauugag uguuucauga augauaaaga uguaaguggc aaaaugaaca      960

gaucucaauu cgaagaauua ugcgccgaau ugcuacagaa aauagaggua ccacuauaua     1020

gccuccuaga acaaacacau cuaaaaguag aagauguuag ugcaguggaa auaguaggag     1080

gcgcuacaag aauaccugca guuaaagaaa gaaucgcuaa auucuucgga aaagauauau     1140

ccacaacacu uaaugcagac gaagcaguag cucgcggcug cgcucuccaa ugugccauuc     1200

uaaguccagc cuucaaaguc agagaauucu cuguaacuga cgcaguuccg uucccuauau     1260

cacuuauaug gaaccacgac agugaagaua cugaaggagu gcaugaagua uucagcagga     1320

accaugccgc uccuuucagc aaaguauuaa cuuucuuacg aaggggacca uucgaauuag     1380

aagcauuuua cucagaucca caaggaguac cauacccuga agcaaaaaua ggccgauucg     1440

uaguacaaaa cgucagcgca caaaaagaug gagaaaaauc aagagucaaa guaaagguac     1500

guguaaauac ccacgguauu uucacaauau caacagcauc caugguagaa aaaguaccua     1560

cagaagaaaa ugaaauguca agcgaagcag auauggaaug cuuaaaucaa agaccaccag     1620

aaaacccaga uacagacaaa aacguacaac aagauaacuc agaagcagga acacaaccac     1680

aaguacaaac cgaugcucaa caaaccucac aaucaccucc aagcccagaa cuuacuucug     1740

aagaaaacaa aaucccagac gcagauaaag ccaacgaaaa aaaagucgac caaccaccag     1800

aagcuaaaaa accaaaaaua aaaguaguaa acguagaacu gcccauagaa gcaaaccuag     1860

uauggcaacu aggaaaagau uuauuaaaca uguacauaga aacugaaggc aaaaugauca     1920

ugcaagauaa acuagaaaaa gaacgcaaug acgcaaaaaa cgcaguagaa gaauauguau     1980

augaauuuag agacaaauua uguggaccau augaaaaauu cauaugcgaa caagaucacc     2040

aaaauuuccu acgacuacuc acugaaacag aagacugguu auaugaagaa ggagaagacc     2100

aagcaaaaca agcuuacgua gacaaacugg aagaacuaau gaaaauaggu acgccuguaa     2160

aaguacguuu ccaagaagca gaagaaagac cgaaaauguu ugaagaauua ggacagagac     2220

uccaacacua ugcaaaaaua gcugcagacu uccgaaacaa agaugaaaaa uauaaccaca     2280

uagaugaaag cgaaaugaaa aaaguugaaa aaucagucaa cgaaguaaug gaauggauga     2340

acaacguaau gaaugcacaa gcaaaaaaaa gucuagacca agacccagua gucagggcgc     2400

aagagauaaa aacgaaaauc aaagaauuaa auaacacuug cgaacccguc guaacgcaac     2460

caaaaccuaa aauagaauca ccaaaacuag agcgcacgcc uaauggucca aacauagaca     2520

aaaaagaaga ggaccuagaa gauaaaaaua acuuuggugc agaacccccc caucaaaacg     2580

gagaaugcua uccaaacgaa aaaaauagug uaaauaugga ucuagacuaa ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  3765
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt13)

<400>  3765
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcug       60

auaaaguaag aagacaaaga cccagaagga gaguuuguug ggcucuagua gcaguauuac      120

uggcagauuu auuagccuua ucagauaccc uugcaguaau guccguagac cuaggaagug      180

aaaguaugaa aguagcaaua guuaaacccg gaguaccaau ggaaauaguc cuuaacaaag      240

aaucuagaag gaaaacucca guuauaguaa cacuaaaaga aaaugaacga uucuucggcg      300

acagugcagc aucaauggcc aucaaaaauc caaaagcaac auuaagauac uuucaacauc      360

uucuuggcaa acaagcugau aauccucaug ucgcauuaua ucaagcaaga uuccccgaac      420

acgaacuaac uuuugaccca caacgucaaa cuguacacuu ucaaauaagu ucacaacuac      480

aauuuagucc agaagaagua cucggaaugg uccugaauua uucaagauca uuagcagaag      540

auuucgcaga acaaccuaua aaagacgcag uaauaaccgu uccuguguuc uuuaaccaag      600

ccgaaaggcg agcaguauua caagcagcuc gaauggcagg auuaaaaguc uuacaauuga      660

uaaaugauaa uacagcaaca gcacuuaguu acgggguauu uagacgaaaa gauaucaaua      720

cgacagcuca aaauauaaug uuuuaugaca ugggaagugg cucaacaguc ugcacaauag      780

uaacauauca aauggucaaa acaaaagaag ccgggaugca accacaacug caaauacgag      840

guguaggauu cgauagaacc uuagggggac uagaaaugga auuaagauua cgagaaagau      900

uagcaggauu auuuaacgaa caaaggaaag gccaacgugc aaaggaugua agagaaaauc      960

caagagcgau ggcaaaacuc cugagagagg cuaauaggcu aaaaacggug cuaagcgcaa     1020

augcggacca uauggcacaa auagaagggu uaauggauga cguagacuuu aaagccaaag     1080

uaacacgcgu agaguucgaa gaauuaugug cugaucuauu ugaaagagua ccggguccag     1140

uucaacaagc guuacaaucg gcagaaaugu cacuugauga aauagaacaa guaauuuuag     1200

uagggggcgc uaccaggguu ccuaggguac aagaaguccu auugaaagcc guggggaaag     1260

aagaauuagg uaagaauaua aacgcagaug aagcugcugc aaugggugca guguaucaag     1320

cagcagcacu aagcaaggca uuuaagguga aaccguucgu uguaagggau gcuguagucu     1380

auccaauauu aguagaauuu acucgcgaag uagaagaaga accaggaaua cauuccuuaa     1440

aacauaauaa aagagucuua uucagcagga ugggacccua uccucagaga aaaguaauaa     1500

ccuucaaccg auacagucau gacuucaauu uccacauaaa cuauggagau uuaggauuuc     1560

uugguccgga agacuuaaga guauuuggaa gucaaaaucu aacaaccgua aaauuaaaag     1620

gcgugggaga cucauuuaag aaguaucccg auuacgaauc aaaaggaauu aaggcacauu     1680

uuaacuuaga cgagagcgga gucuuaagcc uggacagagu ggaaucagua uucgaaacgu     1740

ugguugaaga uucagcugaa gaagaaagua cacuaacgaa auugggaaac accauaaguu     1800

cucuauucgg aggaggcaca acuccagaug caaaagaaaa ugguacagau acuguccaag     1860

aagaagaaga aucaccagca gaaggaucca aggacgaacc aggagagcaa guugaacuua     1920

aagaagaagc agaagcaccc guugaagaug gaucacaacc uccaccaccc gaaccgaaag     1980

gagacgccac gccggaagga gaaaaagcaa cugaaaaaga aaauggagau aaaucagaag     2040

cacaaaaacc aucugaaaaa gccgaggcag gaccagaagg uguagcuccc gcuccggaag     2100

gugaaaagaa acaaaaacca gcacgaaaaa gacgcauggu cgaagaaaua ggaguagaau     2160

uaguaguuuu agacuuaccu gaucucccag aagacaaacu cgcacaauca guacaaaaac     2220

uacaagaucu aacauugaga gaucuggaga aacaagaaag agaaaaagca gcuaauaguc     2280

uagaggcuuu cauuuucgaa acccaagaca aauuauacca accugaauac caggaaguuu     2340

ccacagaaga acaaagggaa gaaaucagug guaaauugag cgcagcuagu acaugguuag     2400

aagaugaagg aguuggagca acgacaguaa uguuaaaaga aaaauuagca gaauuaagga     2460

aauuauguca aggacucuuc uuuagagucg aagaaagaaa gaaauggccc gagagauugu     2520

cagcauuaga caauuuauua aaccauucca gcauguucuu aaaaggugcc agacuuauac     2580

cagaaaugga ucagauauuu acagaagugg aaaugacuac acuagaaaaa guaauuaacg     2640

aaaccugggc auggaaaaau gcaacacuag cagaacaagc caaauuaccg gcgacggaga     2700

aaccaguacu auuaucgaaa gauauagaag caaaaaugau ggcucuagac cgagaagucc     2760

aauaccuuuu aaacaaagcc aaauuuacaa aaccaaggcc aagaccuaaa gacaaaaaug     2820

gaacaagagc ggaaccacca cuaaacgcga gcgcaaguga ccaaggugaa aaaguaauuc     2880

caccagcugg acaaacagaa gacgcugaac ccauaaguga accagaaaaa guagaaacag     2940

gaucagaacc cggagauacu gaaccacuag aguugggagg accaggggcu gagcccgaac     3000

aaaaagaaca aucaacaggc cagaaaagac cgcucaaaaa cgaugaacua uaaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  3766
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt13)

<400>  3766
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

aagaaacgca aacacaggac caaccaaugg aagaagaaga aguugaaaca uuugccuucc      120

aagcugaaau cgcucaacua augucccuca uaauaaacac auuuuacagu aauaaggaaa      180

uauuccuacg agaauuaaua ucaaauagua gugacgcauu agauaaaaua cguuacgaaa      240

gccuaacaga uccgaguaaa cuagacucag gaaaagaacu acacauaaac uuaauaccaa      300

acaaacaaga ccgaacacuc acaauaguag acacagguau aggcaugacg aaagccgauu      360

uaauaaacaa ccucggaacc auugcaaaaa gcggaaccaa ggcauucaug gaagcucuac      420

aagcaggagc ggacaucagc augauaggcc aguucggagu ggguuucuau ucagcauacc      480

ucguagcaga aaaaguaacc gucauaacga agcacaacga cgaugaacaa uaugcauggg      540

aaucauccgc cggaggaagu uucacagucc gaacugacac aggugaaccc augggaagag      600

guacuaaagu aauccuucau cugaaagaag aucaaaccga auaccucgaa gaacgacgaa      660

uaaaagaaau uguaaaaaag cauucacaau ucaucggaua cccuauaaca cucuucguag      720

aaaaagaaag ggauaaagaa guaagcgaug augaagcaga agaaaaggaa gacaaagaag      780

aagaaaaaga aaaagaagaa aaagaaucag aagauaaacc agaaauagaa gacguaggau      840

ccgacgaaga agaagaaaaa aaagacggug acaaaaaaaa aaaaaaaaag auaaaagaaa      900

aauacauaga ccaagaagaa uuaaauaaaa ccaaaccgau auggacgaga aaucccgacg      960

acauaaccaa cgaagaauac ggagaauucu auaaaagccu gaccaacgac ugggaagacc     1020

aucuggcagu caaacacuuc aguguagaag gacaauuaga auucagagca cuacuauuug     1080

uaccgagacg agcaccauuc gacuuauucg aaaauagaaa aaaaaaaaac aacauaaaau     1140

uguacguaag aagggucuuc auaauggaca auugugaaga acuaauaccc gaauaucuaa     1200

acuucauuag aggcguugua gacucagaag accuuccacu caauauauca agagaaaugu     1260

uacaacaaag uaaaauacug aagguaauaa ggaaaaauuu aguaaaaaaa ugcuuggaac     1320

uauucacaga acuagcagaa gacaaagaaa acuacaaaaa auuuuaugaa caauucucaa     1380

aaaacauaaa guuaggaauu cacgaagaua gccaaaauag aaagaaacua ucugaauugu     1440

uacgauauua uacauccgca ucaggugacg aaaugguguc guuaaaagau uacugcacac     1500

gaaugaaaga aaaccaaaaa cauauauauu acauaacagg agaaacaaaa gaucaaguag     1560

caaacagcgc auucgucgaa cgacugagaa agcacggauu agaaguaaua uacaugauag     1620

aaccaauaga ugaauauugu guacaacaau uaaaagaauu cgaaggaaaa acucucguau     1680

caguaacaaa ggaaggacuu gaacuaccag aagaugaaga agaaaaaaaa aaacaagaag     1740

aaaaaaagac aaaauuugaa aaccucugca aaauaaugaa agacauacug gaaaaaaaag     1800

uagaaaaagu aguagucuca aacagacuag ugaccucacc uuguuguaua gucacaagca     1860

cauauggaug gaccgcaaac auggaaagaa uaaugaaagc acaagcauua agagauaacu     1920

caacaauggg uuacauggca gcuaaaaaac aucucgaaau aaauccagau cauucuauaa     1980

uagaaacucu uagacaaaaa gcagaagcag auaaaaacga caagagugua aaagacuuag     2040

ucauacuauu auacgaaacg gcacuacuca gcaguggauu uaguuuagaa gauccacaaa     2100

cacacgcgaa caggaucuac agaaugauua aacuaggauu aggaaucgau gaagaugacc     2160

caacagcaga cgacacauca gcagcaguaa cagaagaaau gccaccacua gaaggggacg     2220

augacacuag ccgaauggaa gaaguagacu aaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  3767
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt13)

<400>  3767
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcucaaaacu agacucagga aaaggacuac acauaaaccu aguaccaaac aaacaaaacc      120

aaacacuaac aauaguagac acaagaauag gaaugacaaa aacagaccua auaaacaacc      180

uaggaacagu aacaaaaagc ggaacaaaag cauucaugga agcacuacaa gcagacgcag      240

acauaagcau gauaggacac uucggaguag gauucuacuc agcauaccua guagcaaaaa      300

aaguaacagu aauaucaaaa cacaacaacg acgaacaaua cacaugggaa ucaagcgcag      360

gaggaagcuu cacaguaaga acagacgaau aaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  3768
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt13)

<400>  3768
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

aagaaguaca ucauggagaa gaagaagucg aaacguuugc uuuccaagcg gaaauagcgc      120

aacuaaugag ccuaauaaua aacacauucu auaguaacaa agaaaucuuc uugagggaau      180

uaauuucaaa cgccuccgau gcauuagaca aaauaagaua cgaaagcuua acagacccau      240

caaaauuaga uagcggaaaa gagcuaaaaa ucgacauaau accuaaccca caagaacgua      300

cacugacacu uguagauaca ggaauaggaa ugacaaaagc agaccuaaua aacaaccuag      360

gaacuauagc uaaaucaggc acgaaagccu ucauggaagc cuuacaagca ggagcagaua      420

uaucaaugau aggacaauuu ggagugggau ucuacagcgc auaccuagua gcagaaaaag      480

uagucguaau aaccaaacau aaugacgacg aacaauacgc augggaaagc ucggcaggag      540

gcagcuuuac aguaagagca gaucauggcg aaccuauagg aaggggcacc aaagucaucc      600

uacaucucaa agaagaucaa acagaauauu uagaagaaag acgagugaaa gagguaguca      660

aaaagcauuc ccaauuuaua ggcuauccaa uaaccuuaua ccuagaaaaa gaaagagaaa      720

aagaaauauc agacgacgaa gccgaagaag aaaaaggaga aaaagaagaa gaagauaaag      780

acgaugaaga aaaaccaaaa auagaagaug uaggaagcga ugaagaagac gacucaggaa      840

aagacaaaaa aaaaaagaca aaaaaaauaa aagaaaaaua uaucgaucaa gaagaacuca      900

acaaaacaaa acccauaugg acaagaaauc cagacgacau aacacaggaa gaauacggag      960

aauucuauaa aagccuuacg aaugacuggg aagaucaucu agcaguaaaa cacuucucug     1020

uagaaggaca acuagaauuc cgagcccuac uauucauacc aagacgcgca ccauucgacc     1080

uauucgaaaa uaaaaaaaaa aaaaacaaua uaaaauuaua uguacggaga guguucauaa     1140

uggacaguug cgaugaacua auaccagaau acuuaaacuu uauaagagga gugguagacu     1200

cagaagaccu accccuaaau auaagccggg agauguuaca acaaagcaaa auauuaaaag     1260

uaaucaggaa gaacauugua aaaaaauguc uggaacuauu uucagaguua gcagaagaua     1320

aagaaaacua caaaaaauuc uacgaagcau ucucaaaaaa uuuaaaauua gggauacaug     1380

aagacagcac aaacagaaga agacugagcg aacuacuaag auaucauaca agucaaagug     1440

gagacgaaau gacuucacua agugaauacg uaucaagaau gaaagaaaca caaaaaucua     1500

uuuacuacau aacuggagaa ucaaaagaac agguagcaaa cagcgcauuu gucgaacgag     1560

uaagaaaacg aggauucgaa guaguuuaua ugacagaacc uaucgaugaa uauugcgucc     1620

aacaacuaaa agaauuugac ggaaaaucac uugucagugu aacaaaagaa ggacuagaac     1680

ugcccgaaga cgaagaagaa aaaaaaaaaa uggaagaauc aaaggcuaaa uucgaaaauc     1740

uaugcaaauu aaugaaagaa auacucgaca aaaaaguaga aaaaguaacc auaagcaauc     1800

gacuaguauc aaguccuugc uguauaguca caucaacaua uggauggaca gcgaauaugg     1860

aaaggauaau gaaagcccaa gcacuuagag acaauaguac aaugggauac augauggcca     1920

aaaagcaucu agaaauaaau ccugaccacc caaucguaga aacacuaaga caaaaagcag     1980

aagcagauaa aaacgacaaa gcaguuaaag acuuaguugu cuuauuauuc gaaacagcac     2040

uacucucaag uggauucuca cuagaagacc cccaaacaca uaguaacaga auauaccgaa     2100

ugauuaaauu gggauuagga aucgacgaag acgaaguggc agccgaagaa ccaaaugccg     2160

caguacccga ugaaauacca ccccuagaag gagacgaaga cgcaaguaga auggaagaag     2220

uagauuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  3769
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt13)

<400>  3769
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaggg       60

cauuaugggu ucuaggacua uguugcguac uacuaacguu cggaucagua agagcagacg      120

augaaguaga ugucgauggc acaguagagg aagaccuagg aaaaucaaga gaaggaagcc      180

guacagacga cgaaguagug caaagagaag aggaagcaau ccaguuggau ggacuaaaug      240

caagucaaau aagagaacua agagaaaaau cagaaaaauu cgcauuucaa gcagaaguga      300

acagaaugau gaaacuaaua aucaauucau uauauaaaaa caaagaaaua uuccugagag      360

aacuaauaag caacgcaagu gaugcuuuag auaaaauacg acuaauuagc uuaacagacg      420

aaaaugcauu aagcggaaau gaagaguuaa caguaaaaau aaaaugugac aaagaaaaaa      480

acuuacucca ugugacagac acaggaguag gaaugacccg cgaggaauug guaaaaaauc      540

uaggaacgau agcuaaaagc ggaacaagug aauuucuuaa uaaaaugaca gaagcacaag      600

aagacggcca aucaacaagu gaacuaauag gacaauucgg aguugguuuu uauagugcuu      660

uuuuaguugc ugacaaagua auagucacgu cgaaacauaa uaacgacaca caacacaucu      720

gggaaaguga cucgaaugaa uuuucaguua uagcagaucc aagaggaaau acgcuaggca      780

gagggacaac aauaacauua guacuuaaag aagaagcauc agauuauuua gaauuagaua      840

caauaaaaaa ccuaguaaaa aaauauaguc aauucauaaa uuuccccaua uauguaugga      900

guaguaaaac agaaacggua gaagaaccaa uggaagaaga agaagcagcu aaagaagaaa      960

aagaggaaag ugacgaugaa gcagcaguug aagaagaaga agaagaaaaa aagccgaaaa     1020

cuaaaaaagu cgaaaaaacg guaugggacu gggaacuuau gaacgauaua aagcccauau     1080

ggcagagacc gagcaaagaa guagaagaag augaauauaa agcauuuuac aaaucauuua     1140

guaaagaauc agacgaucca auggcuuaca uacauuuuac agccgaggga gaaguaacau     1200

ucaaaucaau uuuguuugua ccaacaagug cucccagagg gcuauucgau gaauacggau     1260

caaaaaaaag cgacuauaua aaacucuaug uaagaagagu auucaucacc gacgacuucc     1320

acgauaugau gccuaaauac cuaaauuucg uaaaaggagu cguagauagu gaugacuuac     1380

cauuaaaugu aagcagagaa acucuccaac aacauaaauu acuaaaagug auacguaaaa     1440

aauuaguaag aaaaacacuc gacaugauaa aaaaaauagc ggaugauaaa uauaaugaua     1500

cauucuggaa agaauucgga acaaauauaa aacuuggcgu aauagaagau cacucuaaua     1560

gaacaagacu agcaaaacuc uuaagguucc aaagcucaca ucacccaacc gauauaacuu     1620

cauuagauca auauguagaa aggaugaaag aaaaacaaga uaaaauauau uuuauggcag     1680

gaucaucaag aaaagaagcu gaaaguagcc cauucgucga aagacuucuu aaaaaagggu     1740

augaaguuau auauuugaca gaaccaguag augaauauug uauacaggca cuaccagaau     1800

ucgaugguaa aagauuccaa aacguagcaa aagaaggcgu aaaauucgac gaaagugaga     1860

aaacuaagga aucacgagaa gcgguagaaa aagaauucga gcccuuacuc aauuggauga     1920

aagacaaagc acuaaaagau aaaaucgaaa aagcuguggu cagucaaaga uuaacagaau     1980

caccaugcgc auuaguugca agucaauaug gguggucagg aaauauggaa agaauaauga     2040

aagcgcaagc auaucaaacu ggaaaggaua uaucgacuaa cuacuacgca ucgcaaaaga     2100

aaacauucga aauaaauccu agacacccau uaauaagaga caugcuacga agaaucaaag     2160

aagaugaaga cgacaagaca guacuagauc uagcaguagu auuauuugaa acagcaacau     2220

uaagaucggg uuaccuucuu ccggauacaa aagcauacgg cgacagaaua gaaagaaugc     2280

ucagacuauc acucaacauc gacccagaug caaaagugga agaggaacca gaagaagaac     2340

cagaagaaac agcagaagau acgacagaag acacugaaca agaugaggac gaagaaaugg     2400

acgugggaac ugacgaagaa gaagaaacug caaaagaaag cacugcugag aaagaugaac     2460

uauaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  3770
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt13)

<400>  3770
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcaa       60

gagaacuaag agcucuauua cucuggggaa gaagacuacg accauuauua agagccccug      120

cauuagcagc ugucccaggc gguaaaccua uccuaugucc aagaaggacg acagcgcaau      180

uaggaccuag aagaaaucca gcuuggagcu uacaagcagg uagauuauuu aguacacaaa      240

cagcagaaga uaaagaagaa ccucuacaua gcauaaucag uaguacagaa ucuguacaag      300

gaaguacaag uaaacacgaa uuucaagccg aaacaaagaa acuccuugac aucguagcua      360

gaagucuaua uucagaaaaa gaaguauuca ucagggaauu aauuucaaau gcaucagaug      420

ccuuagaaaa acuaagacac aaacugguau ccgauggaca agcccuacca gaaauggaga      480

uacauuuaca aacaaacgca gaaaaaggua ccaucacaau ccaggauaca gguauaggca      540

ugacucaaga agaacuuguu ucuaaccuag gaacuauagc aagaucuggc aguaaagcau      600

uccuagaugc uuuacaaaac caagcagaag caucuucaaa aauaauagga caauuuggug      660

uaggauucua uagugcauuu augguggcug aucguguaga aguuuauuca cggucagcag      720

cuccaggauc auuaggauac caauggcuau cugaugguuc aggagucuuc gagauugcag      780

aagcauccgg aguaagaaca ggcacaaaaa ucauaauaca ccuaaaaucu gauugcaaag      840

aauuuucuag cgaagcaaga guaagagaug uagucacaaa auacuccaac uucgucucau      900

ucccacuaua cuuaaauggc agacgaauga auacucuaca agcuauaugg augauggauc      960

caaaagaugu ccgggaaugg caacaugaag aguucuauag auacguugcu caagcucacg     1020

acaaaccacg auauacacuu cauuacaaaa ccgaugcacc acuuaauaua agaucaauau     1080

uuuauguacc agacaugaaa ccaucuaugu ucgauguauc cagagaauua ggaucaucug     1140

uagcauuaua cucaagaaaa guguuaauac aaacuaaagc aacagauauc uuaccaaaau     1200

ggcuucgauu cauaagagga guuguagauu cagaagacau cccacuaaac uuaucgagag     1260

aauuacuaca agaaucagca cuuauuagaa aacuaagaga uguccuacaa caaagauuaa     1320

uaaaauucuu uauagaucaa ucaaagaaag augcagaaaa auacgcaaaa uucuucgaag     1380

acuauggacu auuuaugagg gaaggcauag uaacugcaac agaacaagaa guuaaagaag     1440

acauugcaaa acuacuaaga uaugaaaguu ccgcguuacc uucaggccaa cucacgaguc     1500

uaagcgaaua ugcaagccgc augcgugcag gaacuagaaa cauauacuac cuaugugcgc     1560

cuaacaggca ucucgcagaa cauuccccuu acuacgaagc aaugaaaaag aaagauacag     1620

aaguacucuu cugcuucgaa caauuugaug aacucacauu auuacaucua cgcgaguucg     1680

acaaaaagaa auuaauaucc guagaaacag acaucgucgu agaccacuau aaagaagaaa     1740

aauuugaaga cagauccccc gcagcagaau guuuaaguga aaaagaaaca gaagaauuaa     1800

uggcauggau gagaaacgua cuuggcucaa gaguuacuaa cguuaaagua acucuacgac     1860

uagacacaca uccugccaug guaacggucu uagaaauggg agcagcaaga cacuuccuua     1920

gaaugcaaca auuagcaaaa acccaagaag aaagagcaca auuacuacaa ccaacauuag     1980

aaaucaaucc uaggcaugca uuaauaaaga aacuaaacca gcuuagagca agcgaacccg     2040

gucuugcaca acuauuagua gaucaaaucu augaaaacgc caugauagca gcaggucuag     2100

uugacgaccc cagagcaaug guagguagac uuaacgaacu acucgucaaa gcauuagaaa     2160

ggcauuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  3771
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt13)

<400>  3771
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

aaauaucauc acuaccuaca caacuauuca aaugcugcuu cugcgacuuc cuaaaaguaa      120

aaaugcacac aaugucaucc ucacaccuau ucuaccuagc acuaugccua cuaacauuca      180

caucaucagc aacagccgga ccagaaacac uaugcggagc agaacuagua gacgcauuac      240

aauucguaug cggagacaga ggauucuacu ucaacaaacc aacaggauac ggaucaucau      300

caagaagagc accacaaaca ggaauaguag acgaaugcug uuucagauca ugcgacuuaa      360

gaagacuaga aauguacugc gcaccauuaa aaccagcaaa aagcgcaaga ucaguaagag      420

cacaaagaca uacagacaug ccaaaaacac aaaaagaagu acaccuaaaa aacgcaucaa      480

gaggaucagc aggaaacaaa aacuacagaa uguaaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  3772
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt13)

<400>  3772
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

uaccaauggg aaaaucaaug cuaguacuau uaacauuucu agccuucgca ucauguugca      120

uagcagcaua cagaccaagu gaaacucuau guggaggaga auuaguagau acacuacaau      180

uuguaugugg agauagaggu uucuauuuca guagaccagc aagcagagua ucaagaagaa      240

guagaggaau aguagaagaa ugcuguuuca gaucauguga ccuagcacua cuagaaacau      300

auugcgcaac accagcaaaa ucagaaagag auguaucaac accaccaaca guauuaccag      360

auaacuuucc aagauacccu guaggaaaau uuuuccaaua cgauacaugg aaacaaucaa      420

cacaaagacu aagaagagga cuaccagcac uacuaagagc aagaagagga cacguacuag      480

caaaagaacu agaagcauuu agagaagcaa aaagacauag accauuaaua gcauuaccaa      540

cacaagaucc agcacacgga ggagcaccac cagaaauggc aucaaacaga aaauaaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  3773
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt13)

<400>  3773
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

cauuuucaac aucagcauuc ggaccaguag cauucucacu aggauuacua cuaguacuac      120

cagcagcauu cccagcccca guaccacccg gagaagacuc caaagacgua gccgccccac      180

acagacaacc acuaacauca uccgaaagaa uagauaaaca aauaagauac auacuagacg      240

gaaucucagc acuaagaaaa gaaacaugca acaaaucaaa caugugcgaa ucaucaaaag      300

aagcacuagc agaaaacaau uuaaaccuac caaaaauggc agaaaaagac ggcugcuucc      360

aaucaggauu caaugaagaa accugccuag uaaaaauaau aacaggauua cucgaauucg      420

aaguauacuu agaauaccua caaaacagau ucgaaucauc agaagaacaa gcaagagcag      480

uacaaaugag cacaaaagua cucauacaau uccuacaaaa aaaagcaaaa aaucuagacg      540

caauaacaac accagaccca acaacaaacg caucacuacu aacaaaacua caagcacaaa      600

accaauggcu acaagacaug acaacucacc uaauacucag auccuucaaa gaauuucuac      660

aauccucacu aagagcacua agacaaaugu aaggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  3774
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt13)

<400>  3774
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccau       60

uacuaugguu aagagguuuu cuauuagcau caugcuggau aauaguaaga ucaaguccaa      120

caccaggaag ugaaggucau agugcagcac cugacugucc uaguugcgca uuagcagcau      180

uaccaaaaga cguaccaaac agccagccag aaaugguaga agcaguaaaa aaacauauau      240

uaaauaugcu acaucuaaaa aaaaggccag acguaacaca accaguacca aaagcggcuu      300

uauuaaaugc aauaagaaaa uuacauguag guaaaguagg agaaaacggu uacguagaaa      360

uagaggauga cauaggccga agagcagaaa ugaaugaacu aauggaacaa acaagugaaa      420

uaauaacauu ugcagaauca ggaacagcaa gaaaaacgcu acacuucgaa auaagcaaag      480

aaggaagcga ucuuagugug guagaaagag cagaaguaug guuauuccug aagguaccca      540

aagccaaucg aacgagaaca aaaguaacaa uaagauuauu ucaacaacaa aaacauccac      600

aagguucacu agauacagga gaggaagccg aagaaguagg uuuaaaagga gaaagaucug      660

aauuauuauu guccgaaaaa guaguagaug ccagaaaaag uaccuggcau guauuuccag      720

ugaguucauc aauacaaaga uuacuagauc aagguaaauc aucacuagau guaagaauag      780

caugugaaca augucaagaa aguggagcua guuuaguacu auuaggaaag aaaaaaaaaa      840

aggaggaaga aggagaagga aaaaaaaaag gaggaggaga aggaggagcg ggagcagaug      900

aagaaaaaga acaaagucau agaccauucu uaauguuaca agcaagacaa agcgaagauc      960

auccacacag aagaagacga cgaggacuag aaugcgaugg aaaagucaau auauguugua     1020

aaaaacaauu uuuuguauca uuuaaagaca uaggauggaa cgauuggaua auagcgccau     1080

caggauauca cgcuaacuau ugugaaggag aauguccaag ccauauagca ggaacgagug     1140

gaagcucauu aucauuucac agcacgguaa uaaaccauua uagaaugaga ggacauagcc     1200

cauuugcaaa uuuaaaauca uguuguguac cuacaaaacu acguccaaug agcaugcuau     1260

auuacgacga cggacaaaau auuauaaaga aagauaucca aaauaugaua guagaagagu     1320

gcggauguag cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  3775
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt13)

<400>  3775
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaug       60

gauuaccagg gagagcauua ggagcagcau gucuauuauu auuagcagca gguugguuag      120

gcccagaagc auggggaucu ccaacaccac caccaacacc agcagcaccc ccaccaccac      180

caccaccagg aaguccagga ggaagccaag auacauguac aagcuguggu ggauuuagaa      240

gaccagaaga auuaggaaga guagauggag acuuuuuaga agccguaaaa agacacauac      300

uuucaagauu acaaaugaga ggaaggccaa auauaacaca ugcaguacca aaggcagcaa      360

ugguuacagc auuaagaaaa uuacacgcag gaaaaguaag agaagauggu agaguagaaa      420

uaccacauuu agacgggcac gcaucaccag gugcagaugg gcaagaaaga guaagugaga      480

uaauuagcuu ugcagaaaca gauggauuag caucaucaag aguacgauua uauuucuuua      540

uaaguaacga aggaaaucaa aaucuauucg uagugcaagc aucacuaugg uuauauuuaa      600

aauuauugcc auauguacua gaaaaaggaa gcagaagaaa gguaagaguu aaaguuuauu      660

uucaagaaca aggucaugga gaucgaugga auaugguaga aaaacgagua gauuuaaaaa      720

gaucaggaug gcauacauuu ccacuaacag aagcaauaca agcauuauuc gaaagaggcg      780

aaagaagacu gaauuuagac gugcaaugug acucaugcca agaauuagca gugguuccag      840

ucuuuguaga cccaggagaa gaaagccaua gaccauuugu aguaguacaa gcaagacuag      900

gagauaguag acauagaaua agaaaaagag guuuagaaug ugacggaaga acaaauuuau      960

guugcagaca acaauucuuu auugauuuua gguuaauagg uuggaaugau uggauaauag     1020

caccaacagg auauuaugga aauuauugug aaggaagcug uccagcauau uuagcuggug     1080

uaccagguuc agcuaguagu uuucacacag caguagucaa ucaauaucgu augcgaggau     1140

uaaauccugg uacuguaaau agcuguugua uaccaacaaa acuaaguaca augucaaugu     1200

uauauuuuga ugaugaauau aauauaguua aaagagaugu uccaaauaug auaguagaag     1260

aauguggaug cgcuuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  3776
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt13)

<400>  3776
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcau       60

uacgagucuu acuuuuaaca gcauuaacuc ugugccacgg auuuaaucuu gauacagaaa      120

augcaaugac auuucaagaa aacgcacgag gauuuggcca gucgguagua caguuacagg      180

guagcagggu uguugucggu gccccacaag aaauaguagc agccaaucaa agagguucac      240

uauaccaaug ugauuacucu acaggaaguu gugagcccau aagauuacaa guacccgucg      300

aagcagucaa uaugucccua ggacuaaguu uagcagcaac aacuagccca ccacaauuac      360

uagcuugcgg cccaaccgua caccagacau guucugaaaa uaccuauguc aaagguuuau      420

gcuucuuauu cgguaguaau uuaagacagc aaccacaaaa auuuccugaa gcacuacgcg      480

gauguccuca agaagacucc gacauagcau uucuaauaga cggaaguggc aguauaauac      540

cccaugacuu uaggagaaug aaagaauuug uguccacagu aauggaacaa cuaaagaaau      600

cuaagacacu uuucucauua augcaauaua gugaagaauu uagaauacau uucaccuuca      660

aagaauuuca aaacaacccg aauccaagau cccuaguuaa accaauaacc caguuacuag      720

gaagaacaca uacugccaca ggcauucgaa aaguaguacg agaacuauuu aacauuacua      780

auggagcuag aaagaacgcu uucaaaauuc uaguaguuau aacugaugga gagaaauucg      840

gagacccucu uggauacgaa gauguuauac cagaagccga uagagaagga gucauaagau      900

auguaauagg aguaggcgau gccuuccgaa gcgaaaaauc cagacaggaa cuaaauacaa      960

uagcuagcaa accaccgagg gaccacguuu uucaagucaa uaauuuugaa gcauuaaaaa     1020

ccauucaaaa ccaacuaagg gagaaaauau ucgcuauaga aggaacacaa accggaucua     1080

guaguagcuu ugaacaugaa augucccaag aagguuuuuc ugcugcgaua acuucaaaug     1140

gcccacuacu aucaacaguc gguaguuaug auugggccgg aggaguauuc cuuuauacaa     1200

guaaagaaaa aucaacauuc auaaauauga caagaguaga cucugauaug aaugaugccu     1260

auuuaggaua cgcagcagca aucauacuac gcaacagagu ccaaucacuc guacuaggug     1320

cccccagaua ccaacauauc ggucuggucg cuauguuucg ucaaaauaca gguauguggg     1380

aaaguaaugc aaauguaaaa gguacucaaa uaggcgcaua uuuuggugcu ucauuaugca     1440

gcguugacgu ggauucgaac gguaguacag acuuaguguu aauaggcgca ccccacuacu     1500

acgaacaaac aagagguggg cagguaucag uaugcccucu acccagaggc cgugccagau     1560

ggcaauguga cgcaguacua uauggagaac aagggcaacc augggguaga uuuggggcug     1620

cauugacagu uuuaggagac guaaauggag auaaacuaac ggauguugcu auaggagccc     1680

cuggugagga agauaauaga ggagcgguau accuauuuca uggaacaucu ggaaguggaa     1740

uuucaccuag ucacucacaa aggauagcag gauccaagcu cuccccacga uuacaauauu     1800

uuggacagag ccuaucggga ggucaagauc uaacuaugga ugguuuggug gaucucaccg     1860

uaggcgcuca aggucaugug cuacuauuac gaucacaacc uguacuuaga guaaaagcca     1920

uaauggaguu caacccaaga gaaguagcuc guaauguauu cgaaugcaac gaucaaguug     1980

uaaaaggcaa agaagcagga gaagugcgug ucugucuuca uguucagaaa agcacacgug     2040

aucgauuaag agagggccaa auucaaucug uaguuacaua cgacuuagcc uuagacuccg     2100

gacgaccaca cucucgcgca gucuuuaaug aaacgaaaaa cucaacacga aggcaaacac     2160

aaguacuagg auuaacucaa acaugcgaaa cccuuaaacu acaauuaccu aacuguaucg     2220

aagacccagu aucuccaauc guauugagac uaaauuuuuc cuuaguaggc acaccacuua     2280

gugcuuuugg aaaucuaaga ccggucuuag cagaagaugc ucaaagauua uuuaccgcac     2340

uguucccauu cgagaaaaac uguggaaacg auaauauaug ccaagacgac uuaucuauua     2400

cauucucauu caugucguua gauugucuag uaguaggagg acccagagaa uuuaauguaa     2460

ccgucacagu ucgaaaugac ggagaagacu cauauagaac ccaaguaaca uucuucuuuc     2520

cguuagaucu cagcuaucgg aaaguaucaa cauuacaaaa ccaacgaagc caacgaucau     2580

ggaggcucgc augugaaagc gcuuccagua cggaaguaag uggagcacuc aaaucuacau     2640

cuugcucuau uaaccaccca auauuuccgg aaaacaguga ggucacuuuu aauaucaccu     2700

ucgacguaga uagcaaagcc aguuuaggaa auaaacuucu ucucaaggca aacguaacuu     2760

cugaaaauaa uaugccaaga accaacaaaa cagaguucca acuagaauua ccagucaaau     2820

acgcaguaua uaugguagua acaagucaug gaguuuccac gaaauaccua aacuuuacug     2880

caucagaaaa cacaagcaga guaaugcaac aucaauacca aguaucaaau uuaggacaac     2940

gaaguuuacc aauaucguua guuuuccugg ucccagucag auugaaucaa acaguaaucu     3000

gggauagacc acaaguaaca uuuucagaaa aucucucauc aaccugucau accaaggaaa     3060

gauuaccuuc acauucagau uuucuagcag aacuacgcaa agcuccagua guuaauugcu     3120

caaucgcagu augucaaaga auacaaugug acaucccauu cuuuggcauu caagaagaau     3180

uuaacgcuac auuaaaagga aaucuuaguu uugauuggua caucaaaacc agucauaacc     3240

auuuacuaau agucucuacu gcugaaauac uauuuaauga uucuguauuu acucuauuac     3300

caggacaagg agcuuuuguu cgaucacaaa cagaaacuaa aguagaacca uucgaagucc     3360

caaauccauu accauuaauc guggguucuu cuguaggcgg cuuauuacuu uuagcauuaa     3420

uaacugcugc cuuguauaaa uuaggauuuu ucaaaaggca auauaaagau augaugucug     3480

aaggaggucc acccggagcc gaaccacaau aaggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  3777
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt13)

<400>  3777
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguucu       60

cccucaaaac acuaccauuc uuacuacuac uccauguaca aauauccaaa gcauucccug      120

uaucaucaaa agaaaaaaac acaaaaacag uacaagacua ccuagaaaaa uucuaccaau      180

uaccuucaaa ccaauaccaa ucaacaagaa aaaacggaac aaacguuaua guagaaaaac      240

uaaaagaaau gcaacguuuc uuugguuuaa auguaacagg uaaaccaaac gaagaaacau      300

uagacaugau gaaaaaacca agauguggag uaccagacuc cggcggauuu auguuaacac      360

caggaaaucc aaaaugggaa agaacaaauu uaacuuaccg aauaagaaac uacacaccuc      420

aauuaagcga agcagaagua gaaagagcaa uaaaagaugc cuucgaacua ugguccguag      480

caucaccucu aauuuucaca agaauaucac aaggagaagc agacaucaac auagcuuuuu      540

aucaaagaga ucacggagac aauucaccau uugauggacc aaacggaauc cuagcacaug      600

cauuucaacc cggucaagga auaggaggag acgcacacuu cgaugccgaa gaaacaugga      660

ccaacacuuc agcaaacuac aaccuauuuc uaguagcagc acaugaauuc ggccacucau      720

uaggacucgc ucauuccuca gacccuggag cccuaaugua ucccaacuau gcauucagag      780

aaacaucaaa cuauucacua ccucaagacg acauagaugg aauucaagcu aucuacggau      840

uaucaucaaa cccaauucaa ccaacaggac caucaacacc caaaccuugu gacccauccc      900

uaacauuuga cgcuauaaca acacuaagag gagaaauauu auucuucaaa gacagauacu      960

uuuggagaag acacccucaa cuacaaagag uugaaaugaa cuuuauauca uuauucuggc     1020

caucacuacc aacaggaaua caagcagcau acgaagacuu cgauagagac uuaauauucc     1080

uuuucaaagg aaaccaauac ugggcccuaa guggauacga cauauuacaa gguuauccua     1140

aagacauauc aaacuacgga uuuccaucuu caguacaagc aauagacgca gcagucuucu     1200

auagaucaaa aacauacuuu uucguaaacg accaauucug gagauaugac aaccaacgac     1260

aauuuaugga accaggauau ccaaaaucaa uaucaggagc auucccugga auagaaucca     1320

aaguagacgc aguauuucaa caagaacacu ucuuccaugu uuuuucagga ccaagauacu     1380

acgcuuuuga cuuaauagca caaagaguaa caagaguagc aagaggaaac aaauggcuaa     1440

acugccgaua uggauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  3778
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt13)

<400>  3778
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucau       60

uauggcaacc auuaguuuug guacuuuuag uauuaggaug uuguuuugcu gcaccacguc      120

aaagacaaag uacauuaguc cuauuuccag gcgauuuaag aacaaauuua acagacagac      180

aacuugcaga agaauaucua uauagauaug guuauacaag aguagcugaa augagaggug      240

aaucaaaauc ucuaggacca gcauuauuac uacuacaaaa acaguuauca cuaccagaaa      300

ccggggaacu agacucagcu acacuuaaag caaugagaac uccacggugu ggagucccag      360

aucucggucg guuucaaaca uuugaaggag accuuaaaug gcaucaucac aauauaacau      420

auuggauaca gaauuauuca gaagaccuac caagagcggu uauagacgac gcauucgccc      480

gagcauuugc acuauggagu gcuguaacac cauugacuuu uacaagggua uauagucgag      540

augcagauau cguaauacaa uuugguguag cagagcaugg ggauggauac ccuuuugacg      600

guaaagacgg acuucuagca caugcauuuc caccaggacc uggaauacaa ggagaugccc      660

auuuugauga cgacgaacua uggagucuug gaaaaggagu cguaguaccu acaagauuug      720

guaaugcuga uggugcagca ugucauuuuc cuuuuauauu ugaaggacga ucuuacucug      780

caugcacuac agauggacgu ucagauggau uaccauggug uucuacuaca gccaauuaug      840

auacagauga uagauuuggu uuuuguccuu cagaacgauu auauacgcaa gauggaaaug      900

cagauggaaa accuugucaa uucccauuua uauuucaagg acaaucauau ucagcaugua      960

caacagaugg acgaagcgau ggauaucgau ggugugcaac aacagcuaac uacgacagag     1020

auaaauuauu ugguuuuugu ccaacucgcg cugacucaac agucaugggu gguaauagcg     1080

cuggugaauu auguguauuu ccauuuacuu uccuuggcaa agaauacuca acaugcacau     1140

cggaaggaag aggagaugga cgauuauggu gugcaacuac uaguaauuuc gacagugaca     1200

aaaaaugggg auuuuguccg gaccaagggu auucacuuuu cuuaguugca gcacacgaau     1260

ucggucaugc acuuggccua gaccauucau caguaccuga agcucuuaug uacccaaugu     1320

auagauuuac agaaggaccu ccacuccaua aagacgaugu caacggcaua cgccaucuau     1380

augguccacg uccagagccu gaaccaaggc cucccacaac aacaacacca caaccuacug     1440

cuccaccuac aguaugcccg acuggcccac caacaguaca uccaucugaa agaccaacgg     1500

ccggaccaac gggaccuccu ucagcggguc caacaggacc accaacagca ggccccagca     1560

cugccacuac aguaccauua ucaccugugg acgaugcuug uaauguuaau auauuugaug     1620

caauagcuga aauugguaau caacuguauu uauuuaaaga uggaaaauau uggcgauuua     1680

gugaaggacg cggaucuaga ccccaaggac cauuucuaau ugccgauaaa uggccagccc     1740

uaccuagaaa auuagauucu guauuugaag aaagauuauc aaaaaaauua uuuuuuuucu     1800

caggaagaca aguauggguu uauacaggag caucaguacu aggaccuaga agacuagaua     1860

aacuagguuu aggagccgac gucgcacaag uuacaggcgc ccuaagauca ggaagaggaa     1920

aaauguuauu auucagcggu agaagauuau ggagauuuga ugugaaagca caaaugguug     1980

auccaagauc agcuagcgaa gucgaucgaa uguucccagg uguaccauug gauacucaug     2040

auguuuuuca auauagagaa aaagcauauu uuugucaaga uagauuuuau uggcguguuu     2100

caucuaggag ugaauuaaac caaguggauc aaguaggaua uguaacauac gauauacuac     2160

aauguccaga agauuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  3779
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt13)

<400>  3779
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

caggaguauu agcagcauuc cucuucuuau cauggacaca cugccgagca uuaccauuac      120

caucaggagg agacgaagac gaucuaucag aagaagaccu ucaauucgca gaaagauacu      180

uaagaucaua cuaccaccca acaaacuuag cagguauacu aaaagaaaac gcagccucuu      240

caaugacaga aagacuuaga gaaaugcaau cauucuucgg auuagaagua acaggaaaau      300

uagaugacaa uacacuagau guaaugaaaa aaccuagaug cggaguuccu gacguaggag      360

aauauaacgu cuuuccaaga acauuaaaau gguccaaaau gaaccuaaca uauagaauag      420

uaaacuauac accagauaug acccauucag aagucgaaaa agcauucaaa aaagcauuca      480

aaguaugguc agauguaaca ccucuaaacu ucacaagacu acaugacgga auagcagaca      540

ucaugauaag cuuuggaaua aaagaacacg gagauuucua cccauucgac ggaccaucug      600

gauuauuagc ccacgcauuu cccccaggac caaauuaugg aggagacgca cauuucgaug      660

acgaugaaac auggacauca ucaucaaaag gauacaaccu auucuuagua gcagcacacg      720

aauucggaca cucuuuaggc uuagaccauu caaaagaccc cggagcacua auguucccaa      780

uauauacaua uacaggaaaa agccacuuca uguuaccaga cgaugacguc caagguauac      840

aaagucuaua cggaccagga gaugaagauc cuaacccaaa acauccaaaa accccagaca      900

aaugugaucc aucauuauca uuagaugcca uaacaucauu acgaggagaa acaaugauuu      960

ucaaagaccg uuucuucugg cgucuucacc cacaacaagu cgacgcagaa cucuuuuuaa     1020

caaaaucguu uuggccugaa cuaccaaaca gaauagaugc agcauacgaa cacccuaguc     1080

acgacuuaau auuuauuuuu cgaggacgaa aauucugggc ccuaaaugga uacgauauau     1140

uagaaggaua cccuaaaaaa auaucugaac uaggauuacc aaaagaagua aaaaaaauau     1200

cagccgcagu ccacuuugaa gauacaggaa aaacacuucu auuuucaggc aaucaagucu     1260

ggagauacga cgacacaaac cacauaaugg acaaagacua ccccagauua auagaagaag     1320

acuucccagg cauaggugac aaaguagacg caguauacga aaaaaacgga uauauauauu     1380

ucuucaacgg accaauacaa uuugaauacu cuauaugguc aaacagaaua guaagaguaa     1440

ugccagcaaa cuccauuuua uggugcuaag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  3780
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt13)

<400>  3780
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

caccaaacac aacagaagac uacgauacaa ccacagaauu ugauuaugga gacgcaacac      120

caugucaaaa aguaaacgaa agagccuuug gcgcgcaacu acuaccccca uuauacucac      180

uagucuucgu cauaggacua guagguaaua uacuaguagu acuaguauua guccaauaca      240

aaagauuaaa aaauaugaca ucaauauauu uacuaaacuu agcaauauca gauuuacuau      300

uccuauucac auuaccauuc uggaucgacu acaaacuaaa agacgacugg guauuuggag      360

acgcaaugug caaaauacuc ucaggauucu acuacacagg ccuauacucu gaaaucuucu      420

ucauaauacu acuaacaaua gauagauacc uagcaauagu ucaugcagua uucgcauuaa      480

gagccagaac cgucacauuc ggagucauaa caucaauaau aauaugggcc uuagcaauau      540

uagcaucaau gccaggacua uacuuuucua aaacacaaug ggaauucaca caucauacau      600

gcucacuuca cuucccucac gaaucccuaa gagaauggaa acucuuccaa gcauuaaaac      660

ucaaucuuuu cggacuagua cuaccccuac ucguaaugau cauaugcuac acaggaauaa      720

uaaaaauacu acuacgacga ccaaacgaaa aaaaaucaaa agcaguaaga uuaauauucg      780

uaauaaugau caucuucuuc cuuuuuugga ccccuuacaa ccucacaaua cuaauaucag      840

uauuccaaga cuuuuuauuc acacacgaau gugaacaauc cagacaucuc gacuuagcag      900

uacaagucac cgaaguaaua gcauacacac acuguugcgu uaaccccgua auauacgcuu      960

uuguaggaga aagauuccga aaauaucuaa gacaacuauu ucacagacga guugcaguac     1020

acuuagucaa augguuacca uuucuaucag uagauagauu agaaagaguc ucauccacau     1080

caccaucaac cggagaacac gaauuaucag caggauucua aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  3781
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt13)

<400>  3781
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagaa       60

cacuagcaug ccuacuauua cuaggaugcg gauaccuagc acauguacua gcugaagaag      120

cagaaauacc aagagaagua auagaaagac uagcaagauc acaaauacac ucaauaagag      180

accuacaacg acuacuagaa auagacucag ucggaaguga agacucacuc gacacaaguc      240

uaagagcaca cggaguacac gcaacaaaac acguaccaga aaaaagacca cuacccauaa      300

gaagaaaaag aagcauagaa gaagcaguac cagcaguaug caaaacacga acaguaauau      360

acgaaauacc aagaucacaa guagacccaa caucagcaaa cuuccuaaua uggcccccau      420

gcguagaagu aaaaagaugc acaggaugcu gcaacacauc aagcguaaaa ugccaaccaa      480

gcaggguaca ccacagaagc gucaaaguag caaaaguaga auacguaaga aaaaaaccaa      540

aacuaaaaga aguacaagua agacuagaag aacaccuaga augcgcaugu gcaacaacaa      600

gccuaaaucc agauuacaga gaagaagaca caggaagacc aagagaaagc ggaaaaaaaa      660

gaaaaagaaa aagacuaaaa ccaacauaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  3782
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt13)

<400>  3782
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaca       60

gaugcugggc auuauucuua ucauuaugcu guuaccuaag auuaguauca gcagaaggag      120

auccaauacc agaagaacua uacgaaaugc uaagcgauca caguauaaga agcuuugacg      180

aucuacaaag auuacuucac ggcgauccag gagaagaaga cggagcagaa uuagaccuaa      240

auaugacaag aucacacuca ggaggagaau uagaaucacu agcacgugga agaagaagcc      300

uaggaagucu aacaauagca gaaccugcaa ugauagcaga auguaaaaca cgaacagaag      360

uauucgaaau aucaagaaga uuaauagaua gaacaaaugc aaauuucuua guauggccac      420

cauguguaga aguacaaaga ugcaguggau gcugcaauaa cagaaacgua caauguagac      480

caacacaagu acaauuaaga ccaguacaag uaagaaaaau agaaauagua agaaaaaaac      540

caauauuuaa aaaagcaaca gucacauuag aggaccaccu cgcaugcaaa ugugaaaccg      600

uagcagcagc aagaccagua acaagaagcc caggcggaag ccaagaacaa agagcaaaaa      660

caccacaaac uagaguuaca auaagaacag uaagaguacg aaggccccca aaaggaaaac      720

auagaaaauu caaacacaca cacgacaaaa cagcacuaaa agaaacacua ggagcguaag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  3783
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt13)

<400>  3783
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucau       60

uauuuggauu auuacuacuu acaucagcau uagcaggaca aagacaaggu acacaagcag      120

aaagcaaucu aucaagcaaa uuccaauuuu cauccaauaa agaacaaaau ggaguacaag      180

acccacaaca cgaaagaaua auaaccguca gcacaaacgg cucaauacau aguccacgau      240

ucccacauac auauccaaga aacaccguac ucgucuggag auuaguagca guugaagaaa      300

auguauggau ccaauuaaca uucgacgaaa gauuuggauu agaagacccu gaagacgaca      360

uaugcaaaua cgacuuugua gaaguagaag aaccaucaga cggaacaaua uuaggacgau      420

ggugcggauc agguacagua ccugguaaac aaaucucaaa aggcaaccaa auaagaauaa      480

gauucguaag cgaugaauac uucccaagug aaccaggauu cuguauacau uacaauaucg      540

ucaugccaca auucacagaa gcaguaucac caucaguacu accaccauca gcucuaccau      600

uagacuuacu aaauaacgcu auaacagcau uuucaacauu agaagacuua auacgauacu      660

uagaaccaga aagauggcaa cuagaccuag aagaccuaua caggccaaca uggcaacuuc      720

uaggaaaagc auuuguauuu ggaagaaaau cacgaguugu cgaucuaaac cuauuaacag      780

aagaaguaag acuuuacuca ugcacaccaa gaaacuuuuc aguauccaua agagaagaac      840

uaaaaagaac agauacaaua uucuggccag gaugccuacu aguaaaaaga ugcggcggaa      900

auugcgcaug cugcuuacac aacuguaacg aaugccaaug cguaccauca aaaguuacaa      960

aaaaauacca cgaaguacua caauuaagac ccaaaacugg aguuagagga cuacauaaau     1020

cucuaacaga cguagcacua gaacaucacg aagaauguga cugcguuugc cgaggaagca     1080

caggaggcua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  3784
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt13)

<400>  3784
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

gauuaauauu uguauacaca cuaauaugug caaacuucug cucaugcaga gacacauccg      120

caacuccaca aucagcauca auaaaagcuu uaagaaacgc aaaucuaaga agagacgauc      180

uauacagaag agacgaaacc auacaaguaa aaggaaacgg cuacguacaa agcccacgau      240

ucccuaacuc auacccaaga aaucuauuau uaacauggcg acuacacucc caagaaaaca      300

caagaauaca acuaguauuc gauaaccaau ucggauuaga agaagcagaa aacgacauau      360

guagauauga uuucguagaa guagaagaca uaucagaaac aucaacuaua auacgaggaa      420

gauggugcgg acacaaagaa guaccaccac gaauaaaauc aagaacaaac caaauaaaaa      480

uaacuuucaa aucagaugac uacuucguug caaaacccgg auucaaaaua uauuauagcc      540

uacuagaaga cuuccaacca gcagcagcuu cagaaacaaa uugggaauca gucacaagcu      600

caauaucagg aguaucauau aauagcccau caguuacaga cccaacacua aucgccgacg      660

cauuagacaa aaaaauagca gaauucgaua caguagaaga ucuacuaaaa uacuuuaacc      720

cugaaucaug gcaagaagau cuagaaaaca uguaucuaga cacacccaga uacagaggaa      780

gaagcuacca cgacagaaaa ucaaaaguag acuuagacag acuaaaugau gacgcaaaaa      840

gauacucaug cacaccaaga aacuacagcg uaaauauaag agaagaacua aaauuagcaa      900

acguaguauu cuucccaaga ugucuauuag uacaacgcug cggaggaaac uguggaugcg      960

gaacaguaaa cuggcgaagc uguacaugca auuccggaaa aacagucaaa aaauaccacg     1020

aaguacuaca auucgaaccc ggacauauaa aaagaagagg uagagcaaaa acaauggcac     1080

uaguagauau acaauuagac caccaugaaa gaugcgauug uauaugcagc ucuagaccuc     1140

caagauaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  3785
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt13)

<400>  3785
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguca       60

cccauucaaa auucccagca gcaggaaugu caagaccauu agacacauca uuacgauuaa      120

aaacauucuc aucaaaauca gaauaccaac uaguaguaaa ugcaguaaga aaacuacaag      180

aaucaggauu cuauugguca gcaguaacag gaggagaagc aaauuuauua cuaucagcag      240

aaccagcagg aacuuuccua auacgagacu caucagacca acgacacuuc uuuacucuau      300

caguaaaaac acaaucagga acaaaaaacc ucagaauaca augugaagga ggaucauucu      360

cccuacaauc agaccccaga ucaacacaac ccguaccaag auucgacugc guacuaaaac      420

uaguacacca cuacaugcca ccacccggag caccauccuu cccaucucca ccaacagaac      480

caucaucuga aguaccugaa caaccaucag cacaaccacu accuggauca ccaccaagaa      540

gagcauacua cauauacuca ggaggagaaa aaauaccacu aguacuuuca agaccacuau      600

caucuaaugu agcaacacua caacacuuau gccgaaaaac aguaaacggc caccuagacu      660

cauacgaaaa agucacacaa cuaccaggac caauaagaga auucuuagau caauacgacg      720

caccacuaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  3786
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt13)

<400>  3786
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguac       60

caucagcagg acaauuagca uuauuugcac uaggaauagu acuagcagca ugucaagcau      120

uagaaaacuc aacaucacca cuaucagcag acccaccagu agcagcagca guaguaucac      180

auuuuaauga uugcccagac ucacacacac aauucugcuu ucacggaaca uguagauuuc      240

uaguacaaga agacaaacca gcauguguau gucauucagg auauguagga gcaagaugug      300

aacaugcaga uuuauuagca guaguagcag caucacaaaa aaaacaagca auaacugcau      360

uaguaguagu aaguauagua gcauuagcag uauuaauaau aacaugugua uuaauacauu      420

gcugucaagu aagaaaacau ugugaauggu gcagagcauu aauauguaga caugaaaaac      480

cuucagcauu acuaaaagga agaacagcau gcugucacuc agaaacagua guauaaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  3787
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt13)

<400>  3787
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccac       60

caucaggucu acgacuacua ccucucuuac uaccuuuacu auggcuccuc guacuaaccc      120

caggccgacc agcagcuggc cuaucaacau gcaaaacaau agacauggaa uuagucaaaa      180

gaaaaagaau agaagcaauu agaggacaaa uacuaucaaa auuaagauua gccuccccac      240

cuucucaagg agaaguacca ccagguccac uaccugaagc aguccuagca cuauacaacu      300

caacaagaga cagaguagca ggagaauccg cagaaccaga acccgaacca gaagcagacu      360

auuaugcaaa agaagucacc agaguacuaa ugguagaaac acauaaugaa aucuacgaua      420

aauuuaaaca aucaacacau ucaauauaca uguuuuucaa cacaagugaa cuaagagaag      480

caguaccaga accaguauua cuaucacgag ccgaauuaag acuccuaaga cuuaaacuaa      540

aaguagaaca acacguugaa uuauaccaaa aauacucuaa caacucaugg agauacuuau      600

cuaaucgacu acuagcaccc ucagacucac cagaauggcu cucauucgac guaaccggag      660

uaguacgaca auggcuaucc cguggcggug aaauagaagg auucagacua uccgcacacu      720

gcucuugcga cucaagagac aauacauuac aaguagauau aaacggauuc acaacaggaa      780

gaagaggaga cuuagcuaca auccacggaa ugaaccgccc cuuccuacua uuaauggcaa      840

cuccucuaga aagagcacaa cacuuacaau ccucaagaca cagaagagca cuagacacaa      900

acuauuguuu cucaagcacu gaaaaaaacu gcugcguccg acaauuauac auagacuucc      960

gaaaagaucu cggauggaaa uggauacacg aaccaaaagg auaccacgcc aacuucugcc     1020

ucgguccaug uccauauauc uggucacuag auacacaaua cuccaaagua cuagcauuau     1080

auaaccaaca uaauccagga gcaucagcag cgccaugcug cguaccacaa gcauuagaac     1140

cacucccaau aguauacuau gucggaagaa aaccaaaagu agaacaacua ucaaacauga     1200

uagucagauc augcaaaugu ucuuaaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  3788
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt13)

<400>  3788
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

auugcguacu uucagcauuu cuaauauuac accuaguaac agucgcuuua aguuuaagca      120

caugcucaac cuuagacaug gaccaauuua ugagaaaacg aauagaagca auaagaggac      180

aaauauuauc caaacuaaaa cuaacaucac cacccgaaga uuauccagaa ccagaagaag      240

ucccaccaga aguaauauca auauauaaca gcacaagaga ccuccuacaa gaaaaagcau      300

caagaagagc agcagcaugc gaacgagaaa gaucagauga agaauauuac gcuaaagaag      360

uauacaaaau agacaugccc cccuucuuuc caucagaaaa ugcaauacca ccaaccuuuu      420

acagacccua uuuucgaaua guaagauucg auguaucagc cauggaaaaa aacgcaucaa      480

accuagucaa agcggaauuc agaguauucc gacuucaaaa cccaaaagcu agaguucccg      540

aacaacgaau cgaacuauau caaauacuaa aaucaaaaga ccuaaccuca cccacacaaa      600

gauacauaga cucaaaagua guaaaaacca gagcagaggg cgaaugguua ucauucgacg      660

uaacagacgc aguacacgaa uggcuacauc acaaagaccg aaaucucgga uucaaaauau      720

cacuacacug cccaugcugc acauucgucc caucaaacaa cuauauaaua ccaaauaaau      780

cagaagaacu ugaagcaaga uuugcuggaa uagacggaac aaguacauac accucuggag      840

accaaaaaac uauaaaauca acaagaaaaa aaaacucugg caaaacaccu caccuacuau      900

uaaugcuacu acccucauac agacuagaau cacaacaaac aaaccgaaga aaaaaaagag      960

cacuagacgc agcauacugu uucagaaacg uacaagauaa cugcugccuc agaccacuau     1020

auauagacuu caaaagagac cuaggaugga aauggauaca ugaaccaaaa ggcuacaacg     1080

ccaacuucug cgcaggagca ugcccauacu uauggucauc ugacacacag cacucaagag     1140

uacuaucacu auacaacaca auaaauccag aagcuucagc aagucccugc ugcguaucac     1200

aagacuuaga acccuuaacu auauuauauu auaucggaaa aacaccaaaa auagaacaac     1260

uaucaaacau gauaguaaaa ucauguaaau guaguuaagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  3789
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt13)

<400>  3789
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaaa       60

ugcaccucca aagagcccuc gucguucucg cacuacuaaa cuucgcaacc guaucacuau      120

cccuaucaac augcacaacc cuagacuucg gacacauaaa aaaaaaaaga guagaagcaa      180

uccgaggcca aauuuuauca aaacuaagac uaacaucacc accagaaccc acagucauga      240

cacacguacc auaccaaguc cuagcacuau acaacucaac acgagaacua uuagaagaaa      300

ugcacggaga aagagaagaa ggauguacac aagaaaacac ugaaagugaa uacuaugcaa      360

aagaaauaca caaauucgau augauacaag gacuagcaga acacaacgaa cuagcaguau      420

gcccaaaagg aauaacauca aaaguauuuc gauucaacgu aucaucagua gagaaaaauc      480

gaacaaaccu auuuagagcc gaauuuagag uccuaagagu ccccaaucca ucaucaaaaa      540

gaaacgaaca acgcauagaa cuauuucaaa uacuacgccc agacgaacac auagcaaaac      600

aaagauacau agguggaaaa aaccucccaa ccagaggaac agccgaaugg cuaucauucg      660

acguaacaga caccgucaga gaauggcuac uccgcagaga aucaaacuua ggucuagaaa      720

uaucaauaca cugcccaugc cauacauuuc aaccaaaugg agacauauua gaaaacauac      780

augaaguaau ggaaaucaaa uucaaaggag uagacaacga agacgaccac ggacgaggcg      840

accucggcag acuaaaaaaa caaaaagauc accacaaucc acaccuaauc cuaaugauga      900

uaccccccca cagacuagac aacccaggac aaggaggaca acgaaaaaaa agagcacucg      960

acacaaauua uuguuuccga aaucuagaag aaaacugcug cguccgucca cuuuacauag     1020

acuucagaca agaccuagga uggaaauggg uucacgaacc aaaaggauau uaugccaacu     1080

ucugcucagg acccugccca uacuuaagau cagcagacac aacacacucu acaguacuag     1140

gacuauacaa cacacuaaac ccagaagccu cagcaucacc cugcuguguc ccacaagacc     1200

uagaaccuuu aaccauacua uacuacguag gaagaacucc uaaaguagaa caacuuucaa     1260

auaugguagu aaaaucaugc aaaugcucau aaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3790
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt13)

<400>  3790
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

caguagcagu augggcagca cuugcaguag gacucgaauu augggcagca gcacaugcau      120

uaccugcaca aguugcauuc acacccuacg cacccgaacc aggcucaacc uguagauuaa      180

gagaauauua cgaucaaaca gcucaaaugu gcuguucuaa augcucaccu ggccaacaug      240

caaaaguauu uugcacuaaa acaucugaua ccguauguga uucuugugaa gacucaacau      300

auacacaacu auggaacugg guuccagaau gucuaucaug cggaucaaga uguucaucag      360

accaaguuga aacacaagca uguacucgug aacaaaaucg aauuugcaca uguagaccag      420

gaugguauug cgcuuuaucg aaacaagaag gauguagacu augcgcaccu cuuagaaaau      480

gcagaccagg cuuuggaguc gcucgacccg gaacugaaac aucagacgua guaugcaaac      540

cuugugcacc agguacauuc ucuaacacaa caaguucaac agauauuugu agaccacacc      600

aaauauguaa cguaguugcu auaccaggaa acgcaucuau ggaugcagua uguacaucua      660

cgucaccuac cagaucaaug gcaccaggag caguucacuu accacaacca guaucaacaa      720

gaagucaaca cacacaacca acaccugaac ccucaacugc accaagcacu ucauuucuac      780

uaccaauggg ucccucacca ccugcugaag gaucaacagg agacuucgca uuaccugucg      840

gacuuaucgu aggaguuaca gcauuaggac uauuaauaau cgguguagua aauuguguua      900

uuaugacaca aguaaaaaaa aaacccuuau guuuacaaag agaagccaaa guaccucauu      960

uaccagcaga uaaagccaga ggaacccaag guccagaaca acaacauuua uuaaucacag     1020

cucccucauc aucaucauca ucuuuagaau caucagcaag ugcucuagau agaagagcuc     1080

ccacaagaaa ccaaccucaa gcaccaggug ucgaagcauc aggagcuggu gaagcucgug     1140

cuucuacggg aucuucagau ucaucacccg gaggacacgg aacacaagua aauguaacau     1200

gcauaguaaa ugucuguucc aguucggauc auucaucaca auguucauca caagcaucau     1260

cuacuauggg agauacagau aguucaccau cagaaucccc aaaagacgaa caaguaccau     1320

uuucaaaaga agaaugcgca uuuagaucac aauuagaaac accagaaaca uuauuaggau     1380

caacugaaga aaaaccacua ccacuaggcg uaccagaugc aggaaugaaa cccucauaag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  3791
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt13)

<400>  3791
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccag       60

uaaugagauu auuuccaugu uucuuacaau uauuagcagg auuagcauua ccagcaguac      120

caccacaaca augggcguua ucagcaggaa auggaaguag ugaaguagaa guaguaccau      180

uucaagaagu auggggaaga ucauauugua gagcacuaga aagacuagua gauguaguaa      240

gugaauaucc aagcgaagua gaacauaugu uuucaccauc auguguaagu uuauuaagau      300

guacgggaug cuguggagau gaaaauuuac auuguguacc aguagaaaca gcaaauguaa      360

caaugcaauu auuaaaaaua agaaguggag auagaccauc auauguagaa uuaacauuua      420

gccaacaugu aagaugugaa uguagaccau uaagagaaaa aaugaaacca gaaagaagaa      480

gaccaaaagg aagaggaaaa agaagaagag aaaaacaaag accaacagau ugucauuuau      540

guggagaugc aguaccaaga agauaaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  3792
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt13)

<400>  3792
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugacag       60

auagacaaac agauacagcg ccaaguccau cauaccauuu auuaccagga agaagaagaa      120

caguagaugc agcagcgagu agaggacaag gaccagagcc agcaccagga ggaggaguag      180

aaggaguugg agcaagagga guagcgcuaa aauuauuugu acaacuauua ggaugcagua      240

gauucggugg agcaguagua agagcuggag aagcagaacc auccggugca gccagaagcg      300

caaguagugg aagagaagaa ccacaaccag aagaaggaga agaagaagaa gaaaaagaag      360

aggaaagagg accacaaugg agacuuggcg cuagaaaacc ugggagcugg acaggagaag      420

cagcuguaug cgcagauagu gcaccagcag caagagcacc acaagcauua gcaagagcau      480

caggacgagg aggaagagua gcaagaaggg gagccgaaga aaguggaccu ccacauaguc      540

caaguagaag aggaucagca aguagagcug ggccaggaag ggcaucugaa acaaugaauu      600

uuuuauuaag uuggguacau uggaguuuag cuuuauugcu auauuuacau cacgcaaaau      660

ggagucaagc agcaccaaug gcagaaggag ggggacaaaa ucaucacgaa guaguaaaau      720

uuauggaugu uuaucaaagg aguuauuguc auccuauaga aacguuagua gauauauuuc      780

aagaauaccc agaugaaaua gaguauauau uuaaaccgag uuguguacca uuaaugagau      840

guggaggaug uuguaaugac gaaggacuag aauguguacc aacagaagaa agcaauauaa      900

cuaugcagau aaugagaaua aaaccucauc aaggacaaca uauaggagaa augaguuuuu      960

ugcaacacaa uaagugcgaa uguagaccaa aaaaagaucg agcaagacaa gaaaaaaaaa     1020

gcguaagagg uaaagguaaa ggacaaaaaa gaaaaagaaa aaaaaguaga uauaaaagcu     1080

ggaguguaua cguaggggca agauguuguu ugaugccaug gagccuccca ggaccucauc     1140

cguguggacc auguucagag agaagaaaac aucuguuugu acaagaucca caaacaugua     1200

aaugcaguug caaaaauacg gauucaagau guaaagcgag acaauuagaa uuaaaugaaa     1260

ggacauguag augcgauaag ccgagaagau aaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  3793
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt13)

<400>  3793
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

ucuuacuauc auggguacau uggagcuuag cacuauuacu auaccuacac cacgcaaaau      120

ggucacaagc agcaccaaug gcagaaggag gaggacaaaa ccaccaugaa guaguaaaau      180

ucauggaugu auaccaaaga ucauacugcc acccaauaga aacacuagua gacauauucc      240

aagaauaccc agacgaaaua gaauacauau ucaaaccauc auguguacca uuaaugagau      300

gcggaggaug cugcaacgac gaaggacuag aauguguacc aacagaagaa aguaacauaa      360

caaugcaaau aaugagaaua aaaccacauc aaggacaaca cauaggagaa augagcuucc      420

uacaacacaa uaaaugcgaa ugcagaccaa aaaaagacag agcaagacaa gaaaaaaaaa      480

guguaagagg aaaaggaaaa ggacaaaaaa gaaaaagaaa aaaaucaaga uacaaaucau      540

ggucaguaua cguaggagca agaugcugcc uaaugccaug gucacuacca ggaccacacc      600

caugcggacc augcucagaa agaagaaaac accuauucgu acaagaccca caaaccugca      660

aaugcaguug caaaaacaca gacagcagau gcaaagcaag acaauuagaa cuaaacgaaa      720

gaacaugcag augcgauaaa ccacgaagau aaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  3794
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt13)

<400>  3794
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucac       60

cacuauuaag aagauuauua cuagcagcau uacuacaauu agcacccgca caagcaccug      120

uaucacaacc agaugcacca ggacaucaaa gaaaaguagu aucauggaua gacguauaca      180

caagagcaac augucaacca agagaaguag uaguaccauu aacaguagaa cuaaugggaa      240

cagucgcaaa acaacuagua ccaucaugcg uaacaguaca aagaugcgga ggcuguuguc      300

cagacgaugg auuagaaugu guuccaacag gacaacauca aguaagaaug caaauacuaa      360

ugauaagaua cccaucaucu caacuaggag aaauguccuu agaagaacau agucaaugcg      420

aaugcagacc aaaaaaaaaa gauucagcag uaaaaccaga ccgagcagca acaccacauc      480

auagaccaca accacgauca guaccaggcu gggacucagc cccaggagca ccaucaccag      540

cagauauaac ccaucccaca ccugcaccag gaccaucugc acaugcagca ccuucaacaa      600

caucagcauu aacaccagga ccagcagcag cagccgcaga cgcagcugca ucaucaguag      660

caaaaggagg agcauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  3795
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt13)

<400>  3795
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ucuuaggauu cuucucagua gcuugcucau uauuagccgc cgccuuauua ccaggaccaa      120

gagaagcacc agcagcagcc gcagcauuug aaucaggauu agacuuaagu gaugcugaac      180

cagacgcagg agaagcuaca gcauaugcca guaaagacuu agaagaacaa uuaagaucag      240

uaaguuccgu agacgaauua augacaguac ucuauccaga auacuggaaa auguauaaau      300

gucaacuaag aaaaggcgga uggcaacaua auagggaaca agcaaaucua aauucaagaa      360

cagaagaaac uauaaaauuc gcagccgcac acuauaacac ggaaauacua aaaaguauag      420

auaacgaaug gagaaaaaca caaugcaugc caagagaagu augcauagau guaggaaaag      480

aauuuggagu agcaacaaac acauuuuuca aaccaccaug uguaagcgua uacagaugug      540

gcgguugcug caauagcgaa ggauuacaau guaugaacac uagcacuuca uacuuaucaa      600

aaacacuauu ugaaauuaca guaccauuaa gucaaggacc uaaaccagua acgauaaguu      660

uugcaaacca cacaucaugu agauguaugu caaaacuaga uguauauaga caaguacacu      720

caauaauaag aagaucacua ccagcaacac uuccacaaug ccaagcagca aauaaaacau      780

guccaacaaa cuauaugugg aacaaccaca uaugcagaug ucuagcacaa gaagauuuca      840

uguuuaguuc agacgcagga gacgacagca cagauggauu ucaugacaua ugcggaccca      900

acaaagaauu agacgaagaa acuugucaau gcguauguag agcaggacua cgaccagcau      960

cauguggacc acauaaagaa uuagacagaa acaguugcca augcguaugc aaaaauaaac     1020

uauucccauc acaaugugga gcaaaucgag aauuugauga aaacacaugu caauguguau     1080

gcaaaagaac augcccaaga aaucaaccau uaaauccagg uaaaugcgca ugugaaugua     1140

cagaaucacc acaaaaaugc cuauuaaaag gaaagaaauu ucaccaucaa acaugcaguu     1200

guuauagaag accauguaca aauagacaaa aagccuguga accaggauuc uccuacucag     1260

aagaaguaug uagaugugua ccaaguuacu ggaaaagacc acaaauguca uaaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  3796
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt13)

<400>  3796
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguacc       60

gagaaugggu aguaguaaac guauucauga ugcuuuacgu acaacuagua caaggaucau      120

caaaugaaca cggaccagua aaaagaucaa gccaaucaac auuagaaaga ucagaacaac      180

aaauacgagc agcaucauca cucgaagaac uccuaagaau aacacacucc gaagacugga      240

aacuauggcg augcagacua agauuaaaau cauucacauc aauggauuca cgcuccgcau      300

cccacagauc aacaagauuu gccgccacau uuuacgacau agaaacauua aaagucaucg      360

acgaagaaug gcaacgaaca caaugcucac cuagagaaac augcguagaa guagcaucag      420

aacuagguaa auccacaaau accuuuuuua aaccaccuug cguaaacgua uucagaugcg      480

gaggcuguug caacgaagaa ucacuaauuu guaugaacac aucuacaucc uacauaucaa      540

aacaacuauu cgaaauauca guaccacuaa caagcguacc cgaacuaguc cccguaaaag      600

uagcaaacca cacaggaugc aaaugccuac caacagcacc aagacaucca uacuccauaa      660

uacgaagauc aauacaaaua ccagaagaag acagaugcuc acacucaaaa aaacuaugcc      720

cuauagauau gcuaugggac agcaacaaau gcaaaugcgu acuacaagaa gaaaacccuc      780

uagcaggaac cgaagaccac agccaucuac aagaaccagc auuaugcggu ccacauauga      840

uguucgacga agacagaugc gaaugcguau gcaaaacacc augccccaaa gaccuuauac      900

aacacccuaa aaacuguagc ugcuuugaau gcaaagaauc acuagaaaca ugcugccaaa      960

aacacaaauu auuucaccca gacacaugcu caugcgaaga cagaugccca uuccacacca     1020

gaccaugcgc auccgguaaa acagcaugug caaaacacug cagauucccc aaagaaaaaa     1080

gagcagccca aggaccacac ucaagaaaaa auccauaagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  3797
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (wt)

<400>  3797
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucggacg agaccggguu cgagcacuca ggacuguggg      120

uuucugugcu ggcuggucuu cugcugggag ccugccaggc acaccccauc ccugacucca      180

guccucuccu gcaauucggg ggccaagucc ggcagcggua ccucuacaca gaugaugccc      240

agcagacaga agcccaccug gagaucaggg aggaugggac gguggggggc gcugcugacc      300

agagccccga aagucuccug cagcugaaag ccuugaagcc gggaguuauu caaaucuugg      360

gagucaagac auccagguuc cugugccagc ggccagaugg ggcccuguau ggaucgcucc      420

acuuugaccc ugaggccugc agcuuccggg agcugcuucu ugaggacgga uacaauguuu      480

accaguccga agcccacggc cucccgcugc accugccagg gaacaagucc ccacaccggg      540

acccugcacc ccgaggacca gcucgcuucc ugccacuacc aggccugccc cccgcacucc      600

cggagccacc cggaauccug gccccccagc cccccgaugu gggcuccucg gacccucuga      660

gcaugguggg accuucccag ggccgaagcc ccagcuacgc uuccugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  3798
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (wt)

<400>  3798
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucggacg agaccggguu cgagcacuca ggacuguggg      120

uuucugugcu ggcuggucuu cugcugggag ccugccaggc acaccccauc ccugacucca      180

guccucuccu gcaauucggg ggccaagucc ggcagcggua ccucuacaca gaugaugccc      240

agcagacaga agcccaccug gagaucaggg aggaugggac gguggggggc gcugcugacc      300

agagccccga aagucuccug cagcugaaag ccuugaagcc gggaguuauu caaaucuugg      360

gagucaagac auccagguuc cugugccagc ggccagaugg ggcccuguau ggaucgcucc      420

acuuugaccc ugaggccugc agcuuccggg agcugcuucu ugaggacgga uacaauguuu      480

accaguccga agcccacggc cucccgcugc accucccagg gaacaagucc ccacaccggg      540

acccugcacc ccgaggacca gcucgcuucc ugccacuacc aggccugccc cccgcacucc      600

cggagccacc cggaauccug gccccccagc cccccgaugu gggcuccucg gacccucuga      660

gcaugguggg accuucccag ggccgaagcc ccagcuacgc uuccugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  3799
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (wt)

<400>  3799
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc cuccacugcu gcugcugcug uucuggggug      120

uggugucuca cagcuuccca gcgacucuag aaacacaaga gcaagaugug gacuuagucc      180

agaaauaccu ggaaaaauac uacaaccuga agaaugaugg gaggcaaguu gaaaagcgga      240

gaaauagugg cccagugguu gaaaaauuga agcaaaugca ggaauucuuu gggcugaaag      300

ugacugggaa accagaugcu gaaacccuga aggugaugaa gcagcccaga uguggagugc      360

cugauguggc ucaguuuguc cucacugagg ggaacccucg cugggagcaa acacaucuga      420

ccuacaggau ugaaaauuac acgccagauu ugccaagagc agauguggac caugccauug      480

agaaagccuu ccaacucugg aguaauguca caccucugac auucaccaag gucucugagg      540

gucaagcaga caucaugaua ucuuuuguca ggggagauca ucgggacaac ucuccuuuug      600

auggaccugg aggaaaucuu gcucaugcuu uucaaccagg cccagguauu ggaggggaug      660

cucauuuuga ugaagaugaa agguggacca acaauuucag agaguacaac uuacaucgug      720

uugcagcuca ugaacucggc cauucucuug gacucuccca uucuacugau aucggggcuu      780

ugauguaccc uagcuacacc uucaguggug auguucagcu agcucaggau gacauugaug      840

gcauccaagc cauauaugga cguucccaaa auccugucca gcccaucggc ccacaaaccc      900

caaaagcgug ugacaguaag cuaaccuuug augcuauaac uacgauucgg ggagaaguga      960

uguucuuuaa agacagauuc uacaugcgca caaaucccuu cuacccggaa guugagcuca     1020

auuucauuuc uguuuucugg ccacaacugc caaaugggcu ugaagcugcu uacgaauuug     1080

ccgacagaga ugaaguccgg uuuuucaaag ggaauaagua cugggcuguu cagggacaga     1140

augugcuaca cggauacccc aaggacaucu acagcuccuu uggcuucccu agaacuguga     1200

agcauaucga ugcugcucuu ucugaggaaa acacuggaaa aaccuacuuc uuuguugcua     1260

acaaauacug gagguaugau gaauauaaac gaucuaugga uccagguuau cccaaaauga     1320

uagcacauga cuuuccugga auuggccaca aaguugaugc aguuuucaug aaagauggau     1380

uuuucuauuu cuuucaugga acaagacaau acaaauuuga uccuaaaacg aagagaauuu     1440

ugacucucca gaaagcuaau agcugguuca acugcaggaa aaauugagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  3800
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (wt)

<400>  3800
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc cuccacugcu gcugcugcug uucuggggug      120

uggugucuca cagcuuccca gcgacucuag aaacacaaga gcaagaugug gacuuagucc      180

agaaauaccu ggaaaaauac uacaaccuga agaaugaugg gaggcaaguu gaaaagcgga      240

gaaauagugg cccagugguu gaaaaauuga agcaaaugca ggaguucuuu gggcugaaag      300

ugacugggaa accagaugcu gaaacccuga aggugaugaa gcagcccaga uguggagugc      360

cugauguggc ucaguuuguc cucacugagg ggaacccucg cugggagcaa acacaucuga      420

ccuacaggau ugaaaauuac acgccagauu ugccaagagc agauguggac caugccauug      480

agaaagccuu ccaacucugg aguaauguca caccucugac auucaccaag gucucugagg      540

gucaagcaga caucaugaua ucuuuuguca ggggagauca ucgggacaac ucuccuuuug      600

auggaccugg aggaaaucuu gcucaugcuu uucaaccagg cccagguauu ggaggggaug      660

cucauuuuga ugaagaugaa agguggacca acaauuucag agaguacaac uuacaucgug      720

uugcagcuca ugaacucggc cauucucuug gacucuccca uucuacugau aucggggcuu      780

ugauguaccc uagcuacacc uucaguggug auguucagcu agcucaggau gacauugaug      840

gcauccaagc cauauaugga cguucccaaa auccugucca gcccaucggc ccacaaaccc      900

caaaagcgug ugacaguaag cuaaccuuug augcuauaac uacgauucgg ggagaaguga      960

uguucuuuaa agacagauuc uacaugcgca caaaucccuu cuacccggaa guugagcuca     1020

auuucauuuc uguuuucugg ccacaacugc caaaugggcu ugaagcugcu uacgaauuug     1080

ccgacagaga ugaaguccgg uuuuucaaag ggaauaagua cugggcuguu cagggacaga     1140

augugcuaca cggauacccc aaggacaucu acagcuccuu uggcuucccu agaacuguga     1200

agcauaucga ugcugcucuu ucugaggaaa acacuggaaa aaccuacuuc uuuguugcua     1260

acaaauacug gagguaugau gaauauaaac gaucuaugga uccagguuau cccaaaauga     1320

uagcacauga cuuuccugga auuggccaca aaguugaugc aguuuucaug aaagauggau     1380

uuuucuauuu cuuucaugga acaagacaau acaaauuuga uccuaaaacg aagagaauuu     1440

ugacucucca gaaagcuaau agcugguuca acugcaggaa aaauugagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  3801
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (wt)

<400>  3801
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc cuccacugcu gcugcugcug uucuggggug      120

uggugucuca cagcuuuguc cucacugagg ggaacccucg cugggagcaa acacaucuga      180

ccuacaggau ugaaaauuac acgccagauu ugccaagagc agauguggac caugccauug      240

agaaagccuu ccaacucugg aguaauguca caccucugac auucaccaag gucucugagg      300

gucaagcaga caucaugaua ucuuuuguca ggggagauca ucgggacaac ucuccuuuug      360

auggaccugg aggaaaucuu gcucaugcuu uucaaccagg cccagguauu ggaggggaug      420

cucauuuuga ugaagaugaa agguggacca acaauuucag agaguacaac uuacaucgug      480

uugcagcuca ugaacucggc cauucucuug gacucuccca uucuacugau aucggggcuu      540

ugauguaccc uagcuacacc uucaguggug auguucagcu agcucaggau gacauugaug      600

gcauccaagc cauauaugga cguucccaaa auccugucca gcccaucggc ccacaaaccc      660

caaaagcgug ugacaguaag cuaaccuuug augcuauaac uacgauucgg ggagaaguga      720

uguucuuuaa agacagauuc uacaugcgca caaaucccuu cuacccggaa guugagcuca      780

auuucauuuc uguuuucugg ccacaacugc caaaugggcu ugaagcugcu uacgaauuug      840

ccgacagaga ugaaguccgg uuuuucaaag ggaauaagua cugggcuguu cagggacaga      900

augugcuaca cggauacccc aaggacaucu acagcuccuu uggcuucccu agaacuguga      960

agcauaucga ugcugcucuu ucugaggaaa acacuggaaa aaccuacuuc uuuguugcua     1020

acaaauacug gagguaugau gaauauaaac gaucuaugga uccagguuau cccaaaauga     1080

uagcacauga cuuuccugga auuggccaca aaguugaugc aguuuucaug aaagauggau     1140

uuuucuauuu cuuucaugga acaagacaau acaaauuuga uccuaaaacg aagagaauuu     1200

ugacucucca gaaagcuaau agcugguuca acugcaggaa aaauugagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  3802
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (wt)

<400>  3802
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaaaaaua uuuuaaagau ucuuauggau aguuauucua      120

aagaaucuaa aauucaaacu guacguaggg uuacgagugu aucacuuuua gcgguauauc      180

uuacuaugaa uacuucaagu uuaguuuuag caaaaccaau agaaaauacu aaugauacua      240

guauaaaaaa uguggagaaa uuaagaaaug cuccaaauga agagaauagu aaaaagguag      300

aagauaguaa aaaugauaag guagaacaug ugaaaaauau agaagaggca aagguugagc      360

aaguugcacc cgaaguaaaa ucuaaaucaa cuuuaagaag ugcuucuaua gcgaauacua      420

auucugagaa auaugauuuu gaguauuuaa augguuugag cuauacugaa cuuacaaauu      480

uaauuaaaaa uauaaagugg aaucaaauua augguuuauu uaauuauagu acagguucuc      540

aaaaguucuu uggagauaaa aaucguguac aagcuauaau uaaugcuuua caagaaagug      600

gaagaacuua cacugcaaau gauaugaagg guauagaaac uuucacugag guuuuaagag      660

cugguuuuua uuuaggguac uauaaugaug guuuaucuua uuuaaaugau agaaacuucc      720

aagauaaaug uauaccugca augauugcaa uucaaaaaaa uccuaacuuu aagcuaggaa      780

cugcaguuca agaugaaguu auaacuucuu uaggaaaacu aauaggaaau gcuucugcua      840

augcugaagu aguuaauaau uguguaccag uucuaaaaca auuuagagaa aacuuaaauc      900

aauaugcucc ugauuacguu aaaggaacag cuguaaauga auuaauuaaa gguauugaau      960

ucgauuuuuc uggugcugca uaugaaaaag auguuaagac aaugccuugg uauggaaaaa     1020

uugauccauu uauaaaugaa cuuaaggccu uaggucuaua uggaaauaua acaagugcaa     1080

cugagugggc aucugauguu ggaauauacu auuuaaguaa auucggucuu uacucaacua     1140

accgaaauga cauaguacag ucacuugaaa aggcuguaga uauguauaag uaugguaaaa     1200

uagccuuugu agcaauggag agaauaacuu gggauuauga ugggauuggu ucuaauggua     1260

aaaaggugga ucacgauaag uucuuagaug augcugaaaa acauuaucug ccaaagacau     1320

auacuuuuga uaauggaacc uuuauuauaa gagcagggga uaagguaucc gaagaaaaaa     1380

uaaaaaggcu auauugggca ucaagagaag ugaagucuca auuccauaga guaguuggca     1440

augauaaagc uuuagaggug ggaaaugccg augauguuuu aacuaugaaa auauuuaaua     1500

gcccagaaga auauaaauuu aauaccaaua uaaauggugu aagcacugau aauggugguc     1560

uauauauaga accaagaggg acuuucuaca cuuaugagag aacaccucaa caaaguauau     1620

uuagucuuga agaauuguuu agacaugaau auacucacua uuuacaagcg agauaucuug     1680

uagaugguuu augggggcaa gguccauuuu augaaaaaaa uagauuaacu ugguuugaug     1740

aagguacagc ugaauucuuu gcaggaucua cccguacauc ugguguuuua ccaagaaaau     1800

caauauuagg auauuuggcu aaggauaaag uagaucauag auacucauua aagaagacuc     1860

uuaauucagg guaugaugac agugauugga uguucuauaa uuauggauuu gcaguugcac     1920

auuaccuaua ugaaaaagau augccuacau uuauuaagau gaauaaagcu auauugaaua     1980

cagaugugaa aucuuaugau gaaauaauaa aaaaauuaag ugaugaugca aauaaaaaua     2040

cagaauauca aaaccauauu caagaguuag cagauaaaua ucaaggagca ggcauaccuc     2100

uaguaucaga ugauuacuua aaagaucaug gauauaagaa agcaucugaa guauauucug     2160

aaauuucaaa agcugcuucu cuuacaaaca cuaguguaac agcagaaaaa ucucaauauu     2220

uuaacacauu cacuuuaaga ggaacuuaua caggugaaac uucuaaaggu gaauuuaaag     2280

auugggauga aaugaguaaa aaauuagaug gaacuuugga gucccuugcu aaaaauucuu     2340

ggaguggaua caaaacuuua acagcauacu uuacgaauua uagaguuaca agcgauaaua     2400

aaguucaaua ugauguaguu uuccaugggg uuuuaacaga uaaugcggau auuaguaaca     2460

auaaggcucc aauagcaaag guaacuggac caagcacugg ugcuguagga agaaauauug     2520

aauuuagugg aaaagauagu aaagaugaag augguaaaau aguaucauau gauugggauu     2580

uuggcgaugg ugcaacuagu agaggcaaaa auucaguaca ugcuuacaaa aaagcaggaa     2640

cauauaaugu uacauuaaaa guaacugacg auaagggugc aacagcuaca gaaagcuuua     2700

cuauagaaau aaagaacgaa gauacaacaa caccuauaac uaaagaaaug gaaccuaaug     2760

augauauaaa agaggcuaau gguccaauag uugaaggugu uacuguaaaa ggugauuuaa     2820

augguucuga ugaugcugau accuucuauu uugauguaaa agaagauggu gauguuacaa     2880

uugaacuucc uuauucaggg ucaucuaauu ucacaugguu aguuuauaaa gagggagacg     2940

aucaaaacca uauugcaagu gguauagaua agaauaacuc aaaaguugga acauuuaaau     3000

cuacaaaagg aagacauuau guguuuauau auaaacacga uucugcuuca aauauauccu     3060

auucuuuaaa cauaaaagga uuagguaacg agaaauugaa ggaaaaagaa aauaaugauu     3120

cuucugauaa agcuacaguu auaccaaauu ucaauaccac uaugcaaggu ucacuuuuag     3180

gugaugauuc aagagauuau uauucuuuug agguuaagga agaaggcgaa guuaauauag     3240

aacuagauaa aaaggaugaa uuugguguaa cauggacacu acauccagag ucaaauauua     3300

augacagaau aacuuacgga caaguugaug guaauaaggu aucuaauaaa guuaaauuaa     3360

gaccaggaaa auauuaucua cuuguuuaua aauacucagg aucaggaaac uaugaguuaa     3420

ggguaaauaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  3803
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (wt)

<400>  3803
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaaaaaua uuuuaaagau ucuuauggau aguuauucua      120

aagaaucuaa aauucaaacu guacguaggg uuacgagugu aucacuuuua gcgguauauc      180

uuacuaugaa uacuucaagu uuaguuuuag caaaaccaau agaaaauacu aaugauacaa      240

guauaaaaaa uguggagaaa uuaagaaaug cuccaaauga agagaauagu aaaaagguag      300

aagauaguaa aaaugauaag guagaacaug ugaaaaauau agaagaggca aagguugagc      360

aaguugcacc cgaaguaaaa ucuaaaucaa cuuuaagaag ugcuucuaua gcgaauacua      420

auucugagaa auaugauuuu gaguauuuaa augguuugag cuauacugaa cuuacaaauu      480

uaauuaaaaa uauaaagugg aaucaaauua augguuuauu uaauuauagu acagguucuc      540

aaaaguucuu uggagauaaa aaucguguac aagcuauaau uaaugcuuua caagaaagug      600

gaagaacuua cacugcaaau gauaugaagg guauagaaac uuucacugag guuuuaagag      660

cugguuuuua uuuaggguac uauaaugaug guuuaucuua uuuaaaugau agaaacuucc      720

aagauaaaug uauaccugca augauugcaa uucaaaaaaa uccuaacuuu aagcuaggaa      780

cugcaguuca agaugaaguu auaacuucuu uaggaaaacu aauaggaaau gcuucugcua      840

augcugaagu aguuaauaau uguguaccag uucuaaaaca auuuagagaa aacuuaaauc      900

aauaugcucc ugauuacguu aaaggaacag cuguaaauga auuaauuaaa gguauugagu      960

ucgauuuuuc uggugcugca uaugaaaaag auguuaagac aaugccuugg uauggaaaaa     1020

uugauccauu uauaaaugaa cuuaaggccu uaggucuaua uggaaauaua acaagugcaa     1080

cugagugggc aucugauguu ggaauauacu auuuaaguaa auucggucuu uacucaacua     1140

accgaaauga cauaguacag ucacuugaaa aggcuguaga uauguauaag uaugguaaaa     1200

uagccuuugu agcaauggag agaauaacuu gggauuauga ugggauuggu ucuaauggua     1260

aaaaggugga ucacgauaag uucuuagaug augcugaaaa acauuaucug ccaaagacau     1320

auacuuuuga uaauggaacc uuuauuauaa gagcagggga uaagguaucc gaagaaaaaa     1380

uaaaaaggcu auauugggca ucaagagaag ugaagucuca auuccauaga guaguuggca     1440

augauaaagc auuagaggug ggaaaugccg augauguuuu aacuaugaaa auauuuaaua     1500

gcccagaaga auauaaauuu aauaccaaua uaaauggugu aagcacugau aauggugguc     1560

uauauauaga accaagaggg acuuucuaca cuuaugagag aacaccucaa caaaguauau     1620

uuagucuuga agaauuguuu agacaugaau auacucacua uuuacaagcg agauaucuug     1680

uagaugguuu augggggcaa gguccauuuu augaaaaaaa uagauuaacu ugguuugaug     1740

aagguacagc ugaguucuuu gcaggaucua cccguacauc ugguguuuua ccaagaaaau     1800

caauauuagg auauuuggcu aaggauaaag uagaucauag auacucauua aagaagacuc     1860

uuaauucagg guaugaugac agugauugga uguucuauaa uuauggauuu gcaguugcac     1920

auuaccuaua ugaaaaagau augccuacau uuauuaagau gaauaaagcu auauugaaua     1980

cagaugugaa aucuuaugau gaaauaauaa aaaaauuaag ugaugaugca aauaaaaaua     2040

cagaauauca aaaccauauu caagaguuag cagauaaaua ucaaggagca ggcauaccuc     2100

uaguaucaga ugauuacuua aaagaucaug gauauaagaa agcaucugaa guauauucug     2160

aaauuucaaa agcugcuucu cuuacaaaca caaguguaac agcagaaaaa ucucaauauu     2220

uuaacacauu cacuuuaaga ggaacuuaua caggugaaac uucuaaaggu gaauuuaaag     2280

auugggauga aaugaguaaa aaauuagaug gaacuuugga gucccuugcu aaaaauucuu     2340

ggaguggaua caaaacuuua acagcauacu uuacgaauua uagaguuaca agcgauaaua     2400

aaguucaaua ugauguaguu uuccaugggg uuuuaacaga uaaugcggau auuaguaaca     2460

auaaggcucc aauagcaaag guaacuggac caagcacugg ugcuguagga agaaauauug     2520

aauuuagugg aaaagauagu aaagaugaag augguaaaau aguaucauau gauugggauu     2580

uuggcgaugg ugcaacaagu agaggcaaaa auucaguaca ugcuuacaaa aaagcaggaa     2640

cauauaaugu uacauuaaaa guaacugacg auaagggugc aacagcuaca gagagcuuua     2700

cuauagaaau aaagaacgaa gauacaacaa caccuauaac uaaagaaaug gaaccuaaug     2760

augauauaaa agaggcuaau gguccaauag uugaaggugu uacuguaaaa ggugauuuaa     2820

augguucuga ugaugcugau accuucuauu uugauguaaa agaagauggu gauguuacaa     2880

uugaacuucc uuauucaggg ucaucuaauu ucacaugguu aguuuauaaa gagggagacg     2940

aucaaaacca uauugcaagu gguauagaua agaauaacuc aaaaguugga acauuuaaau     3000

cuacaaaagg aagacauuau guguuuauau auaaacacga uucugcuuca aauauauccu     3060

auucuuuaaa cauaaaagga uuagguaacg agaaauugaa ggaaaaagaa aauaaugauu     3120

cuucugauaa agcuacaguu auaccaaauu ucaauaccac uaugcaaggu ucacuuuuag     3180

gugaugauuc aagagauuau uauucuuuug agguuaagga agaaggcgaa guuaauauag     3240

aacuagauaa aaaggaugaa uuugguguaa cauggacacu acauccagag ucaaauauua     3300

augacagaau aacuuacgga caaguugaug guaauaaggu aucuaauaaa guuaaauuaa     3360

gaccaggaaa auauuaucua cuuguuuaua aauacucagg aucaggaaac uaugaguuaa     3420

ggguaaauaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  3804
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (wt)

<400>  3804
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc cauagcgaau acuaauucug agaaauauga uuuugaguau uuaaaugguu      180

ugagcuauac ugaacuuaca aauuuaauua aaaauauaaa guggaaucaa auuaaugguu      240

uauuuaauua uaguacaggu ucucaaaagu ucuuuggaga uaaaaaucgu guacaagcua      300

uaauuaaugc uuuacaagaa aguggaagaa cuuacacugc aaaugauaug aaggguauag      360

aaacuuucac ugagguuuua agagcugguu uuuauuuagg guacuauaau gaugguuuau      420

cuuauuuaaa ugauagaaac uuccaagaua aauguauacc ugcaaugauu gcaauucaaa      480

aaaauccuaa cuuuaagcua ggaacugcag uucaagauga aguuauaacu ucuuuaggaa      540

aacuaauagg aaaugcuucu gcuaaugcug aaguaguuaa uaauugugua ccaguucuaa      600

aacaauuuag agaaaacuua aaucaauaug cuccugauua cguuaaagga acagcuguaa      660

augaauuaau uaaagguauu gaauucgauu uuucuggugc ugcauaugaa aaagauguua      720

agacaaugcc uugguaugga aaaauugauc cauuuauaaa ugaacuuaag gccuuagguc      780

uauauggaaa uauaacaagu gcaacugagu gggcaucuga uguuggaaua uacuauuuaa      840

guaaauucgg ucuuuacuca acuaaccgaa augacauagu acagucacuu gaaaaggcug      900

uagauaugua uaaguauggu aaaauagccu uuguagcaau ggagagaaua acuugggauu      960

augaugggau ugguucuaau gguaaaaagg uggaucacga uaaguucuua gaugaugcug     1020

aaaaacauua ucugccaaag acauauacuu uugauaaugg aaccuuuauu auaagagcag     1080

gggauaaggu auccgaagaa aaaauaaaaa ggcuauauug ggcaucaaga gaagugaagu     1140

cucaauucca uagaguaguu ggcaaugaua aagcuuuaga ggugggaaau gccgaugaug     1200

uuuuaacuau gaaaauauuu aauagcccag aagaauauaa auuuaauacc aauauaaaug     1260

guguaagcac ugauaauggu ggucuauaua uagaaccaag agggacuuuc uacacuuaug     1320

agagaacacc ucaacaaagu auauuuaguc uugaagaauu guuuagacau gaauauacuc     1380

acuauuuaca agcgagauau cuuguagaug guuuaugggg gcaaggucca uuuuaugaaa     1440

aaaauagauu aacuugguuu gaugaaggua cagcugaauu cuuugcagga ucuacccgua     1500

caucuggugu uuuaccaaga aaaucaauau uaggauauuu ggcuaaggau aaaguagauc     1560

auagauacuc auuaaagaag acucuuaauu caggguauga ugacagugau uggauguucu     1620

auaauuaugg auuugcaguu gcacauuacc uauaugaaaa agauaugccu acauuuauua     1680

agaugaauaa agcuauauug aauacagaug ugaaaucuua ugaugaaaua auaaaaaaau     1740

uaagugauga ugcaaauaaa aauacagaau aucaaaacca uauucaagag uuagcagaua     1800

aauaucaagg agcaggcaua ccucuaguau cagaugauua cuuaaaagau cauggauaua     1860

agaaagcauc ugaaguauau ucugaaauuu caaaagcugc uucucuuaca aacacuagug     1920

uaacagcaga aaaaucucaa uauuuuaaca cauucacuuu aagaggaacu uauacaggug     1980

aaacuucuaa aggugaauuu aaagauuggg augaaaugag uaaaaaauua gauggaacuu     2040

uggagucccu ugcuaaaaau ucuuggagug gauacaaaac uuuaacagca uacuuuacga     2100

auuauagagu uacaagcgau aauaaaguuc aauaugaugu aguuuuccau gggguuuuaa     2160

cagauaaugc ggauauuagu aacaauaagg cuccaauagc aaagguaacu ggaccaagca     2220

cuggugcugu aggaagaaau auugaauuua guggaaaaga uaguaaagau gaagauggua     2280

aaauaguauc auaugauugg gauuuuggcg auggugcaac uaguagaggc aaaaauucag     2340

uacaugcuua caaaaaagca ggaacauaua auguuacauu aaaaguaacu gacgauaagg     2400

gugcaacagc uacagaaagc uuuacuauag aaauaaagaa cgaagauaca acaacaccua     2460

uaacuaaaga aauggaaccu aaugaugaua uaaaagaggc uaauggucca auaguugaag     2520

guguuacugu aaaaggugau uuaaaugguu cugaugaugc ugauaccuuc uauuuugaug     2580

uaaaagaaga uggugauguu acaauugaac uuccuuauuc agggucaucu aauuucacau     2640

gguuaguuua uaaagaggga gacgaucaaa accauauugc aagugguaua gauaagaaua     2700

acucaaaagu uggaacauuu aaaucuacaa aaggaagaca uuauguguuu auauauaaac     2760

acgauucugc uucaaauaua uccuauucuu uaaacauaaa aggauuaggu aacgagaaau     2820

ugaaggaaaa agaaaauaau gauucuucug auaaagcuac aguuauacca aauuucaaua     2880

ccacuaugca agguucacuu uuaggugaug auucaagaga uuauuauucu uuugagguua     2940

aggaagaagg cgaaguuaau auagaacuag auaaaaagga ugaauuuggu guaacaugga     3000

cacuacaucc agagucaaau auuaaugaca gaauaacuua cggacaaguu gaugguaaua     3060

agguaucuaa uaaaguuaaa uuaagaccag gaaaauauua ucuacuuguu uauaaauacu     3120

caggaucagg aaacuaugag uuaaggguaa auaaauaagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  3805
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (wt)

<400>  3805
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc cauagcgaau acuaauucug agaaauauga uuuugaguau uuaaaugguu      180

ugagcuauac ugaacuuaca aauuuaauua aaaauauaaa guggaaucaa auuaaugguu      240

uauuuaauua uaguacaggu ucucaaaagu ucuuuggaga uaaaaaucgu guacaagcua      300

uaauuaaugc uuuacaagaa aguggaagaa cuuacacugc aaaugauaug aaggguauag      360

aaacuuucac ugagguuuua agagcugguu uuuauuuagg guacuauaau gaugguuuau      420

cuuauuuaaa ugauagaaac uuccaagaua aauguauacc ugcaaugauu gcaauucaaa      480

aaaauccuaa cuuuaagcua ggaacugcag uucaagauga aguuauaacu ucuuuaggaa      540

aacuaauagg aaaugcuucu gcuaaugcug aaguaguuaa uaauugugua ccaguucuaa      600

aacaauuuag agaaaacuua aaucaauaug cuccugauua cguuaaagga acagcuguaa      660

augaauuaau uaaagguauu gaguucgauu uuucuggugc ugcauaugaa aaagauguua      720

agacaaugcc uugguaugga aaaauugauc cauuuauaaa ugaacuuaag gccuuagguc      780

uauauggaaa uauaacaagu gcaacugagu gggcaucuga uguuggaaua uacuauuuaa      840

guaaauucgg ucuuuacuca acuaaccgaa augacauagu acagucacuu gaaaaggcug      900

uagauaugua uaaguauggu aaaauagccu uuguagcaau ggagagaaua acuugggauu      960

augaugggau ugguucuaau gguaaaaagg uggaucacga uaaguucuua gaugaugcug     1020

aaaaacauua ucugccaaag acauauacuu uugauaaugg aaccuuuauu auaagagcag     1080

gggauaaggu auccgaagaa aaaauaaaaa ggcuauauug ggcaucaaga gaagugaagu     1140

cucaauucca uagaguaguu ggcaaugaua aagcauuaga ggugggaaau gccgaugaug     1200

uuuuaacuau gaaaauauuu aauagcccag aagaauauaa auuuaauacc aauauaaaug     1260

guguaagcac ugauaauggu ggucuauaua uagaaccaag agggacuuuc uacacuuaug     1320

agagaacacc ucaacaaagu auauuuaguc uugaagaauu guuuagacau gaauauacuc     1380

acuauuuaca agcgagauau cuuguagaug guuuaugggg gcaaggucca uuuuaugaaa     1440

aaaauagauu aacuugguuu gaugaaggua cagcugaguu cuuugcagga ucuacccgua     1500

caucuggugu uuuaccaaga aaaucaauau uaggauauuu ggcuaaggau aaaguagauc     1560

auagauacuc auuaaagaag acucuuaauu caggguauga ugacagugau uggauguucu     1620

auaauuaugg auuugcaguu gcacauuacc uauaugaaaa agauaugccu acauuuauua     1680

agaugaauaa agcuauauug aauacagaug ugaaaucuua ugaugaaaua auaaaaaaau     1740

uaagugauga ugcaaauaaa aauacagaau aucaaaacca uauucaagag uuagcagaua     1800

aauaucaagg agcaggcaua ccucuaguau cagaugauua cuuaaaagau cauggauaua     1860

agaaagcauc ugaaguauau ucugaaauuu caaaagcugc uucucuuaca aacacaagug     1920

uaacagcaga aaaaucucaa uauuuuaaca cauucacuuu aagaggaacu uauacaggug     1980

aaacuucuaa aggugaauuu aaagauuggg augaaaugag uaaaaaauua gauggaacuu     2040

uggagucccu ugcuaaaaau ucuuggagug gauacaaaac uuuaacagca uacuuuacga     2100

auuauagagu uacaagcgau aauaaaguuc aauaugaugu aguuuuccau gggguuuuaa     2160

cagauaaugc ggauauuagu aacaauaagg cuccaauagc aaagguaacu ggaccaagca     2220

cuggugcugu aggaagaaau auugaauuua guggaaaaga uaguaaagau gaagauggua     2280

aaauaguauc auaugauugg gauuuuggcg auggugcaac aaguagaggc aaaaauucag     2340

uacaugcuua caaaaaagca ggaacauaua auguuacauu aaaaguaacu gacgauaagg     2400

gugcaacagc uacagagagc uuuacuauag aaauaaagaa cgaagauaca acaacaccua     2460

uaacuaaaga aauggaaccu aaugaugaua uaaaagaggc uaauggucca auaguugaag     2520

guguuacugu aaaaggugau uuaaaugguu cugaugaugc ugauaccuuc uauuuugaug     2580

uaaaagaaga uggugauguu acaauugaac uuccuuauuc agggucaucu aauuucacau     2640

gguuaguuua uaaagaggga gacgaucaaa accauauugc aagugguaua gauaagaaua     2700

acucaaaagu uggaacauuu aaaucuacaa aaggaagaca uuauguguuu auauauaaac     2760

acgauucugc uucaaauaua uccuauucuu uaaacauaaa aggauuaggu aacgagaaau     2820

ugaaggaaaa agaaaauaau gauucuucug auaaagcuac aguuauacca aauuucaaua     2880

ccacuaugca agguucacuu uuaggugaug auucaagaga uuauuauucu uuugagguua     2940

aggaagaagg cgaaguuaau auagaacuag auaaaaagga ugaauuuggu guaacaugga     3000

cacuacaucc agagucaaau auuaaugaca gaauaacuua cggacaaguu gaugguaaua     3060

agguaucuaa uaaaguuaaa uuaagaccag gaaaauauua ucuacuuguu uauaaauacu     3120

caggaucagg aaacuaugag uuaaggguaa auaaauaagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  3806
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (wt)

<400>  3806
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc caugaaaaaa aauauuuuaa agauucuuau ggauaguuau ucuaaagaau      180

cuaaaauuca aacuguacgu aggguuacga guguaucacu uuuagcggua uaucuuacua      240

ugaauacuuc aaguuuaguu uuagcaaaac caauagaaaa uacuaaugau acuaguauaa      300

aaaaugugga gaaauuaaga aaugcuccaa augaagagaa uaguaaaaag guagaagaua      360

guaaaaauga uaagguagaa caugugaaaa auauagaaga ggcaaagguu gagcaaguug      420

cacccgaagu aaaaucuaaa ucaacuuuaa gaagugcuuc uagaaggcgg cgcaagagaa      480

uagcgaauac uaauucugag aaauaugauu uugaguauuu aaaugguuug agcuauacug      540

aacuuacaaa uuuaauuaaa aauauaaagu ggaaucaaau uaaugguuua uuuaauuaua      600

guacagguuc ucaaaaguuc uuuggagaua aaaaucgugu acaagcuaua auuaaugcuu      660

uacaagaaag uggaagaacu uacacugcaa augauaugaa ggguauagaa acuuucacug      720

agguuuuaag agcugguuuu uauuuagggu acuauaauga ugguuuaucu uauuuaaaug      780

auagaaacuu ccaagauaaa uguauaccug caaugauugc aauucaaaaa aauccuaacu      840

uuaagcuagg aacugcaguu caagaugaag uuauaacuuc uuuaggaaaa cuaauaggaa      900

augcuucugc uaaugcugaa guaguuaaua auuguguacc aguucuaaaa caauuuagag      960

aaaacuuaaa ucaauaugcu ccugauuacg uuaaaggaac agcuguaaau gaauuaauua     1020

aagguauuga auucgauuuu ucuggugcug cauaugaaaa agauguuaag acaaugccuu     1080

gguauggaaa aauugaucca uuuauaaaug aacuuaaggc cuuaggucua uauggaaaua     1140

uaacaagugc aacugagugg gcaucugaug uuggaauaua cuauuuaagu aaauucgguc     1200

uuuacucaac uaaccgaaau gacauaguac agucacuuga aaaggcugua gauauguaua     1260

aguaugguaa aauagccuuu guagcaaugg agagaauaac uugggauuau gaugggauug     1320

guucuaaugg uaaaaaggug gaucacgaua aguucuuaga ugaugcugaa aaacauuauc     1380

ugccaaagac auauacuuuu gauaauggaa ccuuuauuau aagagcaggg gauaagguau     1440

ccgaagaaaa aauaaaaagg cuauauuggg caucaagaga agugaagucu caauuccaua     1500

gaguaguugg caaugauaaa gcuuuagagg ugggaaaugc cgaugauguu uuaacuauga     1560

aaauauuuaa uagcccagaa gaauauaaau uuaauaccaa uauaaauggu guaagcacug     1620

auaauggugg ucuauauaua gaaccaagag ggacuuucua cacuuaugag agaacaccuc     1680

aacaaaguau auuuagucuu gaagaauugu uuagacauga auauacucac uauuuacaag     1740

cgagauaucu uguagauggu uuaugggggc aagguccauu uuaugaaaaa aauagauuaa     1800

cuugguuuga ugaagguaca gcugaauucu uugcaggauc uacccguaca ucugguguuu     1860

uaccaagaaa aucaauauua ggauauuugg cuaaggauaa aguagaucau agauacucau     1920

uaaagaagac ucuuaauuca ggguaugaug acagugauug gauguucuau aauuauggau     1980

uugcaguugc acauuaccua uaugaaaaag auaugccuac auuuauuaag augaauaaag     2040

cuauauugaa uacagaugug aaaucuuaug augaaauaau aaaaaaauua agugaugaug     2100

caaauaaaaa uacagaauau caaaaccaua uucaagaguu agcagauaaa uaucaaggag     2160

caggcauacc ucuaguauca gaugauuacu uaaaagauca uggauauaag aaagcaucug     2220

aaguauauuc ugaaauuuca aaagcugcuu cucuuacaaa cacuagugua acagcagaaa     2280

aaucucaaua uuuuaacaca uucacuuuaa gaggaacuua uacaggugaa acuucuaaag     2340

gugaauuuaa agauugggau gaaaugagua aaaaauuaga uggaacuuug gagucccuug     2400

cuaaaaauuc uuggagugga uacaaaacuu uaacagcaua cuuuacgaau uauagaguua     2460

caagcgauaa uaaaguucaa uaugauguag uuuuccaugg gguuuuaaca gauaaugcgg     2520

auauuaguaa caauaaggcu ccaauagcaa agguaacugg accaagcacu ggugcuguag     2580

gaagaaauau ugaauuuagu ggaaaagaua guaaagauga agaugguaaa auaguaucau     2640

augauuggga uuuuggcgau ggugcaacua guagaggcaa aaauucagua caugcuuaca     2700

aaaaagcagg aacauauaau guuacauuaa aaguaacuga cgauaagggu gcaacagcua     2760

cagaaagcuu uacuauagaa auaaagaacg aagauacaac aacaccuaua acuaaagaaa     2820

uggaaccuaa ugaugauaua aaagaggcua augguccaau aguugaaggu guuacuguaa     2880

aaggugauuu aaaugguucu gaugaugcug auaccuucua uuuugaugua aaagaagaug     2940

gugauguuac aauugaacuu ccuuauucag ggucaucuaa uuucacaugg uuaguuuaua     3000

aagagggaga cgaucaaaac cauauugcaa gugguauaga uaagaauaac ucaaaaguug     3060

gaacauuuaa aucuacaaaa ggaagacauu auguguuuau auauaaacac gauucugcuu     3120

caaauauauc cuauucuuua aacauaaaag gauuagguaa cgagaaauug aaggaaaaag     3180

aaaauaauga uucuucugau aaagcuacag uuauaccaaa uuucaauacc acuaugcaag     3240

guucacuuuu aggugaugau ucaagagauu auuauucuuu ugagguuaag gaagaaggcg     3300

aaguuaauau agaacuagau aaaaaggaug aauuuggugu aacauggaca cuacauccag     3360

agucaaauau uaaugacaga auaacuuacg gacaaguuga ugguaauaag guaucuaaua     3420

aaguuaaauu aagaccagga aaauauuauc uacuuguuua uaaauacuca ggaucaggaa     3480

acuaugaguu aaggguaaau aaauaaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  3807
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (wt)

<400>  3807
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc caugaaaaaa aauauuuuaa agauucuuau ggauaguuau ucuaaagaau      180

cuaaaauuca aacuguacgu aggguuacga guguaucacu uuuagcggua uaucuuacua      240

ugaauacuuc aaguuuaguu uuagcaaaac caauagaaaa uacuaaugau acaaguauaa      300

aaaaugugga gaaauuaaga aaugcuccaa augaagagaa uaguaaaaag guagaagaua      360

guaaaaauga uaagguagaa caugugaaaa auauagaaga ggcaaagguu gagcaaguug      420

cacccgaagu aaaaucuaaa ucaacuuuaa gaagugcuuc uagaaggcgg cgcaagagaa      480

uagcgaauac uaauucugag aaauaugauu uugaguauuu aaaugguuug agcuauacug      540

aacuuacaaa uuuaauuaaa aauauaaagu ggaaucaaau uaaugguuua uuuaauuaua      600

guacagguuc ucaaaaguuc uuuggagaua aaaaucgugu acaagcuaua auuaaugcuu      660

uacaagaaag uggaagaacu uacacugcaa augauaugaa ggguauagaa acuuucacug      720

agguuuuaag agcugguuuu uauuuagggu acuauaauga ugguuuaucu uauuuaaaug      780

auagaaacuu ccaagauaaa uguauaccug caaugauugc aauucaaaaa aauccuaacu      840

uuaagcuagg aacugcaguu caagaugaag uuauaacuuc uuuaggaaaa cuaauaggaa      900

augcuucugc uaaugcugaa guaguuaaua auuguguacc aguucuaaaa caauuuagag      960

aaaacuuaaa ucaauaugcu ccugauuacg uuaaaggaac agcuguaaau gaauuaauua     1020

aagguauuga guucgauuuu ucuggugcug cauaugaaaa agauguuaag acaaugccuu     1080

gguauggaaa aauugaucca uuuauaaaug aacuuaaggc cuuaggucua uauggaaaua     1140

uaacaagugc aacugagugg gcaucugaug uuggaauaua cuauuuaagu aaauucgguc     1200

uuuacucaac uaaccgaaau gacauaguac agucacuuga aaaggcugua gauauguaua     1260

aguaugguaa aauagccuuu guagcaaugg agagaauaac uugggauuau gaugggauug     1320

guucuaaugg uaaaaaggug gaucacgaua aguucuuaga ugaugcugaa aaacauuauc     1380

ugccaaagac auauacuuuu gauaauggaa ccuuuauuau aagagcaggg gauaagguau     1440

ccgaagaaaa aauaaaaagg cuauauuggg caucaagaga agugaagucu caauuccaua     1500

gaguaguugg caaugauaaa gcauuagagg ugggaaaugc cgaugauguu uuaacuauga     1560

aaauauuuaa uagcccagaa gaauauaaau uuaauaccaa uauaaauggu guaagcacug     1620

auaauggugg ucuauauaua gaaccaagag ggacuuucua cacuuaugag agaacaccuc     1680

aacaaaguau auuuagucuu gaagaauugu uuagacauga auauacucac uauuuacaag     1740

cgagauaucu uguagauggu uuaugggggc aagguccauu uuaugaaaaa aauagauuaa     1800

cuugguuuga ugaagguaca gcugaguucu uugcaggauc uacccguaca ucugguguuu     1860

uaccaagaaa aucaauauua ggauauuugg cuaaggauaa aguagaucau agauacucau     1920

uaaagaagac ucuuaauuca ggguaugaug acagugauug gauguucuau aauuauggau     1980

uugcaguugc acauuaccua uaugaaaaag auaugccuac auuuauuaag augaauaaag     2040

cuauauugaa uacagaugug aaaucuuaug augaaauaau aaaaaaauua agugaugaug     2100

caaauaaaaa uacagaauau caaaaccaua uucaagaguu agcagauaaa uaucaaggag     2160

caggcauacc ucuaguauca gaugauuacu uaaaagauca uggauauaag aaagcaucug     2220

aaguauauuc ugaaauuuca aaagcugcuu cucuuacaaa cacaagugua acagcagaaa     2280

aaucucaaua uuuuaacaca uucacuuuaa gaggaacuua uacaggugaa acuucuaaag     2340

gugaauuuaa agauugggau gaaaugagua aaaaauuaga uggaacuuug gagucccuug     2400

cuaaaaauuc uuggagugga uacaaaacuu uaacagcaua cuuuacgaau uauagaguua     2460

caagcgauaa uaaaguucaa uaugauguag uuuuccaugg gguuuuaaca gauaaugcgg     2520

auauuaguaa caauaaggcu ccaauagcaa agguaacugg accaagcacu ggugcuguag     2580

gaagaaauau ugaauuuagu ggaaaagaua guaaagauga agaugguaaa auaguaucau     2640

augauuggga uuuuggcgau ggugcaacaa guagaggcaa aaauucagua caugcuuaca     2700

aaaaagcagg aacauauaau guuacauuaa aaguaacuga cgauaagggu gcaacagcua     2760

cagagagcuu uacuauagaa auaaagaacg aagauacaac aacaccuaua acuaaagaaa     2820

uggaaccuaa ugaugauaua aaagaggcua augguccaau aguugaaggu guuacuguaa     2880

aaggugauuu aaaugguucu gaugaugcug auaccuucua uuuugaugua aaagaagaug     2940

gugauguuac aauugaacuu ccuuauucag ggucaucuaa uuucacaugg uuaguuuaua     3000

aagagggaga cgaucaaaac cauauugcaa gugguauaga uaagaauaac ucaaaaguug     3060

gaacauuuaa aucuacaaaa ggaagacauu auguguuuau auauaaacac gauucugcuu     3120

caaauauauc cuauucuuua aacauaaaag gauuagguaa cgagaaauug aaggaaaaag     3180

aaaauaauga uucuucugau aaagcuacag uuauaccaaa uuucaauacc acuaugcaag     3240

guucacuuuu aggugaugau ucaagagauu auuauucuuu ugagguuaag gaagaaggcg     3300

aaguuaauau agaacuagau aaaaaggaug aauuuggugu aacauggaca cuacauccag     3360

agucaaauau uaaugacaga auaacuuacg gacaaguuga ugguaauaag guaucuaaua     3420

aaguuaaauu aagaccagga aaauauuauc uacuuguuua uaaauacuca ggaucaggaa     3480

acuaugaguu aaggguaaau aaauaaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  3808
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  3808
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aauuuuuuaa aaauuauuuu aaauaggggg aagacuauga      120

aaaggaaaug uuuaucuaaa aggcuuaugu uagcuauaac aauggcuaca auauuuacag      180

ugaacaguac auuaccaauu uaugcagcug uagauaaaaa uaaugcaaca gcagcuguac      240

aaaaugaaag uaagagguau acaguaucau auuuaaagac uuuaaauuau uaugacuuag      300

uagauuugcu uguuaagacu gaaauugaga auuuaccaga ccuuuuucag uauaguucag      360

augcaaaaga guucuaugga aauaaaacuc guaugagcuu uaucauggau gaaauuggua      420

gaagggcacc ucaguauaca gagauagauc auaaagguau uccuacuuua guagaaguug      480

uaagagcugg auuuuacuua ggauuccaua acaaggaauu gaaugaaaua aacaagaggu      540

cuuuuaaaga aaggguaaua ccuucuauau uagcaauuca aaaaaauccu aauuuuaaac      600

uagguacuga aguucaagau aaaauaguau cugcaacagg acuuuuagcu gguaaugaaa      660

cagcgccucc agaaguugua aauaauuuua caccaauacu ucaagacugu auaaagaaua      720

uagacagaua cgcucuugau gauuuaaagu caaaagcauu auuuaauguu uuagcugcac      780

cuaccuauga uauaacugag uauuuaagag cuacuaaaga aaaaccagaa aacacuccuu      840

gguaugguaa aauagauggg uuuauaaaug aacuuaaaaa guuagcucuu uauggaaaaa      900

uaaaugauaa uaacucuugg auaauagaua acgguauaua ucauauagca ccuuuaggga      960

aguuacauag caauaauaaa auaggaauag aaacuuuaac agagguuaug aaaguuuauc     1020

cuuauuuaag uaugcaacau uuacaaucag cagaucaaau uaagcgucau uaugauucaa     1080

aagaugcuga aggaaacaaa auaccuuuag auaaguuuaa aaaggaagga aaagaaaaau     1140

acuguccaaa aacuuauaca uuugaugaug gaaaaguaau aauaaaagcu ggugcuagag     1200

uagaagaaga aaaaguuaaa agacuauacu gggcaucaaa ggaaguuaac ucucaauucu     1260

uuagaguaua cggaauagac aaaccauuag aagaagguaa uccagaugau auauuaacaa     1320

ugguuaucua caacaguccc gaagaauaua aacucaauag uguucuauac ggauaugaua     1380

cuaauaaugg ugguauguau auagagccag aaggaacuuu cuucaccuau gaaagagaag     1440

cucaagaaag cacauacaca uuagaagaau uauuuagaca ugaauauaca cauuauuugc     1500

aaggaagaua ugcaguucca ggacaauggg gaagaacaaa acuuuaugac aaugauagau     1560

uaacuuggua ugaagaaggu ggagcagaau uauuugcagg uucuacuaga acuucuggaa     1620

uauuaccaag aaagaguaua guaucaaaua uucauaauac aacaagaaau aauagauaua     1680

agcuuucaga cacuguacau ucuaaauaug gugcuaguuu ugaauucuau aauuaugcau     1740

guauguuuau ggauuauaug uauaauaaag auauggguau auuaaauaaa cuaaaugauc     1800

uugcaaaaaa uaaugauguu gauggauaug auaauuauau uagagauuua aguucuaauu     1860

augcuuuaaa ugauaaauau caagaucaua ugcaggagcg cauagauaau uaugaaaauu     1920

uaacagugcc uuuuguagcu gaugauuauu uaguaaggca ugcuuauaag aacccuaaug     1980

aaauuuauuc ugaaauaucu gaaguagcaa aauuaaagga ugcuaagagu gaaguuaaga     2040

aaucacaaua uuuuaguacc uuuacuuuga gagguaguua cacaggugga gcaucuaagg     2100

ggaaauuaga agaucaaaaa gcaaugaaua aguuuauaga ugauucacuu aagaaauuag     2160

auacguauuc uuggaguggg uauaaaacuu uaacugcuua uuucacuaau uauaaaguug     2220

acucuucaaa uagaguuacu uaugauguag uauuccacgg auauuuacca aacgaaggug     2280

auuccaaaaa uucauuaccu uauggcaaga ucaauggaac uuacaaggga acagagaaag     2340

aaaaaaucaa auucucuagu gaaggcucuu ucgauccaga ugguaaaaua guuucuuaug     2400

aaugggauuu cggagauggu aauaagagua augaggaaaa uccagagcau ucauaugaca     2460

agguaggaac uuauacagug aaauuaaaag uuacugauga caagggagaa ucuucaguau     2520

cuacuacuac ugcagaaaua aaggaucuuu cagaaaauaa acuuccaguu auauauaugc     2580

auguaccuaa auccggagcc uuaaaucaaa aaguuguuuu cuauggaaaa ggaacauaug     2640

acccagaugg aucuaucgca ggauaucaau gggacuuugg ugauggaagu gauuuuagca     2700

gugaacaaaa cccaagccau guauauacua aaaaagguga auauacugua acauuaagag     2760

uaauggauag uaguggacaa augagugaaa aaacuaugaa gauuaagauu acagauccgg     2820

uauauccaau aggcacugaa aaagaaccaa auaacaguaa agaaacugca agugguccaa     2880

uaguaccagg uauaccuguu aguggaacca uagaaaauac aagugaucaa gauuauuucu     2940

auuuugaugu uauaacacca ggagaaguaa aaauagauau aaauaaauua ggguacggag     3000

gagcuacuug gguaguauau gaugaaaaua auaaugcagu aucuuaugcc acugaugaug     3060

ggcaaaauuu aaguggaaag uuuaaggcag auaaaccagg uagauauuac auccaucuuu     3120

acauguuuaa ugguaguuau augccauaua gaauuaauau agaagguuca guaggaagau     3180

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  3809
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  3809
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aauuuuuuaa aaauuauuuu aaauaggggg aagacuauga      120

aaaggaaaug uuuaucuaaa aggcuuaugu uagcuauaac aauggcuaca auauuuacag      180

ugaacaguac auuaccaauu uaugcagcug uagauaaaaa uaaugcaaca gcagcuguac      240

aaaaugaaag uaagagguau acaguaucau auuuaaagac uuuaaauuau uaugacuuag      300

uagauuugcu uguuaagacu gaaauugaga auuuaccaga ccuuuuucag uauaguucag      360

augcaaaaga guucuaugga aauaaaacuc guaugagcuu uaucauggau gaaauuggua      420

gaagggcacc ucaguauaca gagauagauc auaaagguau uccuacuuua guagaaguug      480

uaagagcugg auuuuacuua ggauuccaua acaaggaauu gaaugaaaua aacaagaggu      540

cuuuuaaaga aaggguaaua ccuucuauau uagcaauuca aaaaaauccu aauuuuaaac      600

uagguacuga aguucaagau aaaauaguau cugcaacagg acuuuuagcu gguaaugaaa      660

cagcgccucc agaaguugua aauaauuuua caccaauacu ucaagacugu auaaagaaua      720

uagacagaua cgcucuugau gauuuaaagu caaaagcauu auuuaauguu uuagcugcac      780

cuaccuauga uauaacugag uauuuaagag cuacuaaaga aaaaccagaa aacacuccuu      840

gguaugguaa aauagauggg uuuauaaaug aacuuaaaaa guuagcucuu uauggaaaaa      900

uaaaugauaa uaacucuugg auaauagaua acgguauaua ucauauagca ccuuuaggga      960

aguuacauag caauaauaaa auaggaauag aaacuuuaac agagguuaug aaaguuuauc     1020

cuuauuuaag uaugcaacau uuacaaucag cagaucaaau uaagcgucau uaugauucaa     1080

aagaugcuga aggaaacaaa auaccuuuag auaaguuuaa aaaggaagga aaagaaaaau     1140

acuguccaaa aacuuauaca uuugaugaug gaaaaguaau aauaaaagcu ggugcuagag     1200

uagaagaaga aaaaguuaaa agacuauacu gggcaucaaa ggaaguuaac ucucaauucu     1260

uuagaguaua cggaauagac aaaccauuag aagaagguaa uccagaugau auauuaacaa     1320

ugguuaucua caacaguccc gaagaauaua aacucaauag uguucuauac ggauaugaua     1380

cuaauaaugg ugguauguau auagagccag aaggaacuuu cuucaccuau gaaagagaag     1440

cucaagaaag cacauacaca uuagaagaau uauuuagaca ugaauauaca cauuauuugc     1500

aaggaagaua ugcaguucca ggacaauggg gaagaacaaa acuuuaugac aaugauagau     1560

uaacuuggua ugaagaaggu ggagcagaau uauuugcagg uucuacuaga acuucuggaa     1620

uauuaccaag aaagaguaua guaucaaaua uucauaauac aacaagaaau aauagauaua     1680

agcugucaga cacuguacau ucuaaauaug gugcuaguuu ugaguucuau aauuaugcau     1740

guauguuuau ggauuauaug uauaauaaag auauggguau auuaaauaaa cuaaaugauc     1800

uugcaaaaaa uaaugauguu gauggauaug auaauuauau uagagauuua aguucuaauu     1860

augcuuuaaa ugauaaauau caagaucaua ugcaggagcg cauagauaau uaugaaaauu     1920

uaacagugcc uuuuguagcu gaugauuauu uaguaaggca ugcuuauaag aacccuaaug     1980

aaauuuauuc ugaaauaucu gaaguagcaa aauuaaagga ugcuaagagu gaaguuaaga     2040

aaucacaaua uuuuaguacc uuuacuuuga gagguaguua cacaggugga gcaucuaagg     2100

ggaaauuaga agaucaaaaa gcaaugaaua aguuuauaga ugauucacuu aagaaauuag     2160

auacguauuc uuggaguggg uauaaaacuu uaacugcuua uuucacuaau uauaaaguug     2220

acucuucaaa uagaguuacu uaugauguag uauuccacgg auauuuacca aacgaaggug     2280

auuccaaaaa uucauuaccu uauggcaaga ucaauggaac uuacaaggga acagagaaag     2340

aaaaaaucaa auucucuagu gaaggcucuu ucgauccaga ugguaaaaua guuucuuaug     2400

aaugggauuu cggagauggu aauaagagua augaggaaaa uccagagcau ucauaugaca     2460

agguaggaac uuauacagug aaauuaaaag uuacugauga caagggagaa ucuucaguau     2520

cuacuacuac ugcagaaaua aaggaucuuu cagaaaauaa acuuccaguu auauauaugc     2580

auguaccuaa auccggagcc uuaaaucaaa aaguuguuuu cuauggaaaa ggaacauaug     2640

acccagaugg aucuaucgca ggauaucaau gggacuuugg ugauggaagu gauuuuagca     2700

gugaacaaaa cccaagccau guauauacua aaaaagguga auauacugua acauuaagag     2760

uaauggauag uaguggacaa augagugaaa aaacuaugaa gauuaagauu acagauccgg     2820

uauauccaau aggcacugaa aaagaaccaa auaacaguaa agaaacugca agugguccaa     2880

uaguaccagg uauaccuguu aguggaacca uagaaaauac aagugaucaa gauuauuucu     2940

auuuugaugu uauaacacca ggagaaguaa aaauagauau aaauaaauua ggguacggag     3000

gagcuacuug gguaguauau gaugaaaaua auaaugcagu aucuuaugcc acugaugaug     3060

ggcaaaauuu aaguggaaag uuuaaggcag auaaaccagg uagauauuac auccaucuuu     3120

acauguuuaa ugguaguuau augccauaua gaauuaauau agaagguuca guaggaagau     3180

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  3810
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  3810
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaggaaau guuuaucuaa aaggcuuaug uuagcuauaa      120

caauggcuac aauauuuaca gugaacagua cauuaccaau uuaugcagcu guagauaaaa      180

auaaugcaac agcagcugua caaaaugaaa guaagaggua uacaguauca uauuuaaaga      240

cuuuaaauua uuaugacuua guagauuugc uuguuaagac ugaaauugag aauuuaccag      300

accuuuuuca guauaguuca gaugcaaaag aguucuaugg aaauaaaacu cguaugagcu      360

uuaucaugga ugaaauuggu agaagggcac cucaguauac agagauagau cauaaaggua      420

uuccuacuuu aguagaaguu guaagagcug gauuuuacuu aggauuccau aacaaggaau      480

ugaaugaaau aaacaagagg ucuuuuaaag aaaggguaau accuucuaua uuagcaauuc      540

aaaaaaaucc uaauuuuaaa cuagguacug aaguucaaga uaaaauagua ucugcaacag      600

gacuuuuagc ugguaaugaa acagcgccuc cagaaguugu aaauaauuuu acaccaauac      660

uucaagacug uauaaagaau auagacagau acgcucuuga ugauuuaaag ucaaaagcau      720

uauuuaaugu uuuagcugca ccuaccuaug auauaacuga guauuuaaga gcuacuaaag      780

aaaaaccaga aaacacuccu ugguauggua aaauagaugg guuuauaaau gaacuuaaaa      840

aguuagcucu uuauggaaaa auaaaugaua auaacucuug gauaauagau aacgguauau      900

aucauauagc accuuuaggg aaguuacaua gcaauaauaa aauaggaaua gaaacuuuaa      960

cagagguuau gaaaguuuau ccuuauuuaa guaugcaaca uuuacaauca gcagaucaaa     1020

uuaagcguca uuaugauuca aaagaugcug aaggaaacaa aauaccuuua gauaaguuua     1080

aaaaggaagg aaaagaaaaa uacuguccaa aaacuuauac auuugaugau ggaaaaguaa     1140

uaauaaaagc uggugcuaga guagaagaag aaaaaguuaa aagacuauac ugggcaucaa     1200

aggaaguuaa cucucaauuc uuuagaguau acggaauaga caaaccauua gaagaaggua     1260

auccagauga uauauuaaca augguuaucu acaacagucc cgaagaauau aaacucaaua     1320

guguucuaua cggauaugau acuaauaaug gugguaugua uauagagcca gaaggaacuu     1380

ucuucaccua ugaaagagaa gcucaagaaa gcacauacac auuagaagaa uuauuuagac     1440

augaauauac acauuauuug caaggaagau augcaguucc aggacaaugg ggaagaacaa     1500

aacuuuauga caaugauaga uuaacuuggu augaagaagg uggagcagaa uuauuugcag     1560

guucuacuag aacuucugga auauuaccaa gaaagaguau aguaucaaau auucauaaua     1620

caacaagaaa uaauagauau aagcuuucag acacuguaca uucuaaauau ggugcuaguu     1680

uugaauucua uaauuaugca uguauguuua uggauuauau guauaauaaa gauaugggua     1740

uauuaaauaa acuaaaugau cuugcaaaaa auaaugaugu ugauggauau gauaauuaua     1800

uuagagauuu aaguucuaau uaugcuuuaa augauaaaua ucaagaucau augcaggagc     1860

gcauagauaa uuaugaaaau uuaacagugc cuuuuguagc ugaugauuau uuaguaaggc     1920

augcuuauaa gaacccuaau gaaauuuauu cugaaauauc ugaaguagca aaauuaaagg     1980

augcuaagag ugaaguuaag aaaucacaau auuuuaguac cuuuacuuug agagguaguu     2040

acacaggugg agcaucuaag gggaaauuag aagaucaaaa agcaaugaau aaguuuauag     2100

augauucacu uaagaaauua gauacguauu cuuggagugg guauaaaacu uuaacugcuu     2160

auuucacuaa uuauaaaguu gacucuucaa auagaguuac uuaugaugua guauuccacg     2220

gauauuuacc aaacgaaggu gauuccaaaa auucauuacc uuauggcaag aucaauggaa     2280

cuuacaaggg aacagagaaa gaaaaaauca aauucucuag ugaaggcucu uucgauccag     2340

augguaaaau aguuucuuau gaaugggauu ucggagaugg uaauaagagu aaugaggaaa     2400

auccagagca uucauaugac aagguaggaa cuuauacagu gaaauuaaaa guuacugaug     2460

acaagggaga aucuucagua ucuacuacua cugcagaaau aaaggaucuu ucagaaaaua     2520

aacuuccagu uauauauaug cauguaccua aauccggagc cuuaaaucaa aaaguuguuu     2580

ucuauggaaa aggaacauau gacccagaug gaucuaucgc aggauaucaa ugggacuuug     2640

gugauggaag ugauuuuagc agugaacaaa acccaagcca uguauauacu aaaaaaggug     2700

aauauacugu aacauuaaga guaauggaua guaguggaca aaugagugaa aaaacuauga     2760

agauuaagau uacagauccg guauauccaa uaggcacuga aaaagaacca aauaacagua     2820

aagaaacugc aaguggucca auaguaccag guauaccugu uaguggaacc auagaaaaua     2880

caagugauca agauuauuuc uauuuugaug uuauaacacc aggagaagua aaaauagaua     2940

uaaauaaauu aggguacgga ggagcuacuu ggguaguaua ugaugaaaau aauaaugcag     3000

uaucuuaugc cacugaugau gggcaaaauu uaaguggaaa guuuaaggca gauaaaccag     3060

guagauauua cauccaucuu uacauguuua augguaguua uaugccauau agaauuaaua     3120

uagaagguuc aguaggaaga uaaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  3811
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  3811
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaggaaau guuuaucuaa aaggcuuaug uuagcuauaa      120

caauggcuac aauauuuaca gugaacagua cauuaccaau uuaugcagcu guagauaaaa      180

auaaugcaac agcagcugua caaaaugaaa guaagaggua uacaguauca uauuuaaaga      240

cuuuaaauua uuaugacuua guagauuugc uuguuaagac ugaaauugag aauuuaccag      300

accuuuuuca guauaguuca gaugcaaaag aguucuaugg aaauaaaacu cguaugagcu      360

uuaucaugga ugaaauuggu agaagggcac cucaguauac agagauagau cauaaaggua      420

uuccuacuuu aguagaaguu guaagagcug gauuuuacuu aggauuccau aacaaggaau      480

ugaaugaaau aaacaagagg ucuuuuaaag aaaggguaau accuucuaua uuagcaauuc      540

aaaaaaaucc uaauuuuaaa cuagguacug aaguucaaga uaaaauagua ucugcaacag      600

gacuuuuagc ugguaaugaa acagcgccuc cagaaguugu aaauaauuuu acaccaauac      660

uucaagacug uauaaagaau auagacagau acgcucuuga ugauuuaaag ucaaaagcau      720

uauuuaaugu uuuagcugca ccuaccuaug auauaacuga guauuuaaga gcuacuaaag      780

aaaaaccaga aaacacuccu ugguauggua aaauagaugg guuuauaaau gaacuuaaaa      840

aguuagcucu uuauggaaaa auaaaugaua auaacucuug gauaauagau aacgguauau      900

aucauauagc accuuuaggg aaguuacaua gcaauaauaa aauaggaaua gaaacuuuaa      960

cagagguuau gaaaguuuau ccuuauuuaa guaugcaaca uuuacaauca gcagaucaaa     1020

uuaagcguca uuaugauuca aaagaugcug aaggaaacaa aauaccuuua gauaaguuua     1080

aaaaggaagg aaaagaaaaa uacuguccaa aaacuuauac auuugaugau ggaaaaguaa     1140

uaauaaaagc uggugcuaga guagaagaag aaaaaguuaa aagacuauac ugggcaucaa     1200

aggaaguuaa cucucaauuc uuuagaguau acggaauaga caaaccauua gaagaaggua     1260

auccagauga uauauuaaca augguuaucu acaacagucc cgaagaauau aaacucaaua     1320

guguucuaua cggauaugau acuaauaaug gugguaugua uauagagcca gaaggaacuu     1380

ucuucaccua ugaaagagaa gcucaagaaa gcacauacac auuagaagaa uuauuuagac     1440

augaauauac acauuauuug caaggaagau augcaguucc aggacaaugg ggaagaacaa     1500

aacuuuauga caaugauaga uuaacuuggu augaagaagg uggagcagaa uuauuugcag     1560

guucuacuag aacuucugga auauuaccaa gaaagaguau aguaucaaau auucauaaua     1620

caacaagaaa uaauagauau aagcugucag acacuguaca uucuaaauau ggugcuaguu     1680

uugaguucua uaauuaugca uguauguuua uggauuauau guauaauaaa gauaugggua     1740

uauuaaauaa acuaaaugau cuugcaaaaa auaaugaugu ugauggauau gauaauuaua     1800

uuagagauuu aaguucuaau uaugcuuuaa augauaaaua ucaagaucau augcaggagc     1860

gcauagauaa uuaugaaaau uuaacagugc cuuuuguagc ugaugauuau uuaguaaggc     1920

augcuuauaa gaacccuaau gaaauuuauu cugaaauauc ugaaguagca aaauuaaagg     1980

augcuaagag ugaaguuaag aaaucacaau auuuuaguac cuuuacuuug agagguaguu     2040

acacaggugg agcaucuaag gggaaauuag aagaucaaaa agcaaugaau aaguuuauag     2100

augauucacu uaagaaauua gauacguauu cuuggagugg guauaaaacu uuaacugcuu     2160

auuucacuaa uuauaaaguu gacucuucaa auagaguuac uuaugaugua guauuccacg     2220

gauauuuacc aaacgaaggu gauuccaaaa auucauuacc uuauggcaag aucaauggaa     2280

cuuacaaggg aacagagaaa gaaaaaauca aauucucuag ugaaggcucu uucgauccag     2340

augguaaaau aguuucuuau gaaugggauu ucggagaugg uaauaagagu aaugaggaaa     2400

auccagagca uucauaugac aagguaggaa cuuauacagu gaaauuaaaa guuacugaug     2460

acaagggaga aucuucagua ucuacuacua cugcagaaau aaaggaucuu ucagaaaaua     2520

aacuuccagu uauauauaug cauguaccua aauccggagc cuuaaaucaa aaaguuguuu     2580

ucuauggaaa aggaacauau gacccagaug gaucuaucgc aggauaucaa ugggacuuug     2640

gugauggaag ugauuuuagc agugaacaaa acccaagcca uguauauacu aaaaaaggug     2700

aauauacugu aacauuaaga guaauggaua guaguggaca aaugagugaa aaaacuauga     2760

agauuaagau uacagauccg guauauccaa uaggcacuga aaaagaacca aauaacagua     2820

aagaaacugc aaguggucca auaguaccag guauaccugu uaguggaacc auagaaaaua     2880

caagugauca agauuauuuc uauuuugaug uuauaacacc aggagaagua aaaauagaua     2940

uaaauaaauu aggguacgga ggagcuacuu ggguaguaua ugaugaaaau aauaaugcag     3000

uaucuuaugc cacugaugau gggcaaaauu uaaguggaaa guuuaaggca gauaaaccag     3060

guagauauua cauccaucuu uacauguuua augguaguua uaugccauau agaauuaaua     3120

uagaagguuc aguaggaaga uaaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  3812
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (wt)

<400>  3812
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc cguacaaaau gaaaguaaga gguauacagu aucauauuua aagacuuuaa      180

auuauuauga cuuaguagau uugcuuguua agacugaaau ugagaauuua ccagaccuuu      240

uucaguauag uucagaugca aaagaguucu auggaaauaa aacucguaug agcuuuauca      300

uggaugaaau ugguagaagg gcaccucagu auacagagau agaucauaaa gguauuccua      360

cuuuaguaga aguuguaaga gcuggauuuu acuuaggauu ccauaacaag gaauugaaug      420

aaauaaacaa gaggucuuuu aaagaaaggg uaauaccuuc uauauuagca auucaaaaaa      480

auccuaauuu uaaacuaggu acugaaguuc aagauaaaau aguaucugca acaggacuuu      540

uagcugguaa ugaaacagcg ccuccagaag uuguaaauaa uuuuacacca auacuucaag      600

acuguauaaa gaauauagac agauacgcuc uugaugauuu aaagucaaaa gcauuauuua      660

auguuuuagc ugcaccuacc uaugauauaa cugaguauuu aagagcuacu aaagaaaaac      720

cagaaaacac uccuugguau gguaaaauag auggguuuau aaaugaacuu aaaaaguuag      780

cucuuuaugg aaaaauaaau gauaauaacu cuuggauaau agauaacggu auauaucaua      840

uagcaccuuu agggaaguua cauagcaaua auaaaauagg aauagaaacu uuaacagagg      900

uuaugaaagu uuauccuuau uuaaguaugc aacauuuaca aucagcagau caaauuaagc      960

gucauuauga uucaaaagau gcugaaggaa acaaaauacc uuuagauaag uuuaaaaagg     1020

aaggaaaaga aaaauacugu ccaaaaacuu auacauuuga ugauggaaaa guaauaauaa     1080

aagcuggugc uagaguagaa gaagaaaaag uuaaaagacu auacugggca ucaaaggaag     1140

uuaacucuca auucuuuaga guauacggaa uagacaaacc auuagaagaa gguaauccag     1200

augauauauu aacaaugguu aucuacaaca gucccgaaga auauaaacuc aauaguguuc     1260

uauacggaua ugauacuaau aaugguggua uguauauaga gccagaagga acuuucuuca     1320

ccuaugaaag agaagcucaa gaaagcacau acacauuaga agaauuauuu agacaugaau     1380

auacacauua uuugcaagga agauaugcag uuccaggaca auggggaaga acaaaacuuu     1440

augacaauga uagauuaacu ugguaugaag aagguggagc agaauuauuu gcagguucua     1500

cuagaacuuc uggaauauua ccaagaaaga guauaguauc aaauauucau aauacaacaa     1560

gaaauaauag auauaagcuu ucagacacug uacauucuaa auauggugcu aguuuugaau     1620

ucuauaauua ugcauguaug uuuauggauu auauguauaa uaaagauaug gguauauuaa     1680

auaaacuaaa ugaucuugca aaaaauaaug auguugaugg auaugauaau uauauuagag     1740

auuuaaguuc uaauuaugcu uuaaaugaua aauaucaaga ucauaugcag gagcgcauag     1800

auaauuauga aaauuuaaca gugccuuuug uagcugauga uuauuuagua aggcaugcuu     1860

auaagaaccc uaaugaaauu uauucugaaa uaucugaagu agcaaaauua aaggaugcua     1920

agagugaagu uaagaaauca caauauuuua guaccuuuac uuugagaggu aguuacacag     1980

guggagcauc uaaggggaaa uuagaagauc aaaaagcaau gaauaaguuu auagaugauu     2040

cacuuaagaa auuagauacg uauucuugga guggguauaa aacuuuaacu gcuuauuuca     2100

cuaauuauaa aguugacucu ucaaauagag uuacuuauga uguaguauuc cacggauauu     2160

uaccaaacga aggugauucc aaaaauucau uaccuuaugg caagaucaau ggaacuuaca     2220

agggaacaga gaaagaaaaa aucaaauucu cuagugaagg cucuuucgau ccagauggua     2280

aaauaguuuc uuaugaaugg gauuucggag augguaauaa gaguaaugag gaaaauccag     2340

agcauucaua ugacaaggua ggaacuuaua cagugaaauu aaaaguuacu gaugacaagg     2400

gagaaucuuc aguaucuacu acuacugcag aaauaaagga ucuuucagaa aauaaacuuc     2460

caguuauaua uaugcaugua ccuaaauccg gagccuuaaa ucaaaaaguu guuuucuaug     2520

gaaaaggaac auaugaccca gauggaucua ucgcaggaua ucaaugggac uuuggugaug     2580

gaagugauuu uagcagugaa caaaacccaa gccauguaua uacuaaaaaa ggugaauaua     2640

cuguaacauu aagaguaaug gauaguagug gacaaaugag ugaaaaaacu augaagauua     2700

agauuacaga uccgguauau ccaauaggca cugaaaaaga accaaauaac aguaaagaaa     2760

cugcaagugg uccaauagua ccagguauac cuguuagugg aaccauagaa aauacaagug     2820

aucaagauua uuucuauuuu gauguuauaa caccaggaga aguaaaaaua gauauaaaua     2880

aauuagggua cggaggagcu acuuggguag uauaugauga aaauaauaau gcaguaucuu     2940

augccacuga ugaugggcaa aauuuaagug gaaaguuuaa ggcagauaaa ccagguagau     3000

auuacaucca ucuuuacaug uuuaauggua guuauaugcc auauagaauu aauauagaag     3060

guucaguagg aagauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  3813
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (wt)

<400>  3813
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc cguacaaaau gaaaguaaga gguauacagu aucauauuua aagacuuuaa      180

auuauuauga cuuaguagau uugcuuguua agacugaaau ugagaauuua ccagaccuuu      240

uucaguauag uucagaugca aaagaguucu auggaaauaa aacucguaug agcuuuauca      300

uggaugaaau ugguagaagg gcaccucagu auacagagau agaucauaaa gguauuccua      360

cuuuaguaga aguuguaaga gcuggauuuu acuuaggauu ccauaacaag gaauugaaug      420

aaauaaacaa gaggucuuuu aaagaaaggg uaauaccuuc uauauuagca auucaaaaaa      480

auccuaauuu uaaacuaggu acugaaguuc aagauaaaau aguaucugca acaggacuuu      540

uagcugguaa ugaaacagcg ccuccagaag uuguaaauaa uuuuacacca auacuucaag      600

acuguauaaa gaauauagac agauacgcuc uugaugauuu aaagucaaaa gcauuauuua      660

auguuuuagc ugcaccuacc uaugauauaa cugaguauuu aagagcuacu aaagaaaaac      720

cagaaaacac uccuugguau gguaaaauag auggguuuau aaaugaacuu aaaaaguuag      780

cucuuuaugg aaaaauaaau gauaauaacu cuuggauaau agauaacggu auauaucaua      840

uagcaccuuu agggaaguua cauagcaaua auaaaauagg aauagaaacu uuaacagagg      900

uuaugaaagu uuauccuuau uuaaguaugc aacauuuaca aucagcagau caaauuaagc      960

gucauuauga uucaaaagau gcugaaggaa acaaaauacc uuuagauaag uuuaaaaagg     1020

aaggaaaaga aaaauacugu ccaaaaacuu auacauuuga ugauggaaaa guaauaauaa     1080

aagcuggugc uagaguagaa gaagaaaaag uuaaaagacu auacugggca ucaaaggaag     1140

uuaacucuca auucuuuaga guauacggaa uagacaaacc auuagaagaa gguaauccag     1200

augauauauu aacaaugguu aucuacaaca gucccgaaga auauaaacuc aauaguguuc     1260

uauacggaua ugauacuaau aaugguggua uguauauaga gccagaagga acuuucuuca     1320

ccuaugaaag agaagcucaa gaaagcacau acacauuaga agaauuauuu agacaugaau     1380

auacacauua uuugcaagga agauaugcag uuccaggaca auggggaaga acaaaacuuu     1440

augacaauga uagauuaacu ugguaugaag aagguggagc agaauuauuu gcagguucua     1500

cuagaacuuc uggaauauua ccaagaaaga guauaguauc aaauauucau aauacaacaa     1560

gaaauaauag auauaagcug ucagacacug uacauucuaa auauggugcu aguuuugagu     1620

ucuauaauua ugcauguaug uuuauggauu auauguauaa uaaagauaug gguauauuaa     1680

auaaacuaaa ugaucuugca aaaaauaaug auguugaugg auaugauaau uauauuagag     1740

auuuaaguuc uaauuaugcu uuaaaugaua aauaucaaga ucauaugcag gagcgcauag     1800

auaauuauga aaauuuaaca gugccuuuug uagcugauga uuauuuagua aggcaugcuu     1860

auaagaaccc uaaugaaauu uauucugaaa uaucugaagu agcaaaauua aaggaugcua     1920

agagugaagu uaagaaauca caauauuuua guaccuuuac uuugagaggu aguuacacag     1980

guggagcauc uaaggggaaa uuagaagauc aaaaagcaau gaauaaguuu auagaugauu     2040

cacuuaagaa auuagauacg uauucuugga guggguauaa aacuuuaacu gcuuauuuca     2100

cuaauuauaa aguugacucu ucaaauagag uuacuuauga uguaguauuc cacggauauu     2160

uaccaaacga aggugauucc aaaaauucau uaccuuaugg caagaucaau ggaacuuaca     2220

agggaacaga gaaagaaaaa aucaaauucu cuagugaagg cucuuucgau ccagauggua     2280

aaauaguuuc uuaugaaugg gauuucggag augguaauaa gaguaaugag gaaaauccag     2340

agcauucaua ugacaaggua ggaacuuaua cagugaaauu aaaaguuacu gaugacaagg     2400

gagaaucuuc aguaucuacu acuacugcag aaauaaagga ucuuucagaa aauaaacuuc     2460

caguuauaua uaugcaugua ccuaaauccg gagccuuaaa ucaaaaaguu guuuucuaug     2520

gaaaaggaac auaugaccca gauggaucua ucgcaggaua ucaaugggac uuuggugaug     2580

gaagugauuu uagcagugaa caaaacccaa gccauguaua uacuaaaaaa ggugaauaua     2640

cuguaacauu aagaguaaug gauaguagug gacaaaugag ugaaaaaacu augaagauua     2700

agauuacaga uccgguauau ccaauaggca cugaaaaaga accaaauaac aguaaagaaa     2760

cugcaagugg uccaauagua ccagguauac cuguuagugg aaccauagaa aauacaagug     2820

aucaagauua uuucuauuuu gauguuauaa caccaggaga aguaaaaaua gauauaaaua     2880

aauuagggua cggaggagcu acuuggguag uauaugauga aaauaauaau gcaguaucuu     2940

augccacuga ugaugggcaa aauuuaagug gaaaguuuaa ggcagauaaa ccagguagau     3000

auuacaucca ucuuuacaug uuuaauggua guuauaugcc auauagaauu aauauagaag     3060

guucaguagg aagauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  3814
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (wt)

<400>  3814
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc caugaaaagg aaauguuuau cuaaaaggcu uauguuagcu auaacaaugg      180

cuacaauauu uacagugaac aguacauuac caauuuaugc agcuguagau aaaaauaaug      240

caacagcagc uagaaggcgg cgcaagagag uacaaaauga aaguaagagg uauacaguau      300

cauauuuaaa gacuuuaaau uauuaugacu uaguagauuu gcuuguuaag acugaaauug      360

agaauuuacc agaccuuuuu caguauaguu cagaugcaaa agaguucuau ggaaauaaaa      420

cucguaugag cuuuaucaug gaugaaauug guagaagggc accucaguau acagagauag      480

aucauaaagg uauuccuacu uuaguagaag uuguaagagc uggauuuuac uuaggauucc      540

auaacaagga auugaaugaa auaaacaaga ggucuuuuaa agaaagggua auaccuucua      600

uauuagcaau ucaaaaaaau ccuaauuuua aacuagguac ugaaguucaa gauaaaauag      660

uaucugcaac aggacuuuua gcugguaaug aaacagcgcc uccagaaguu guaaauaauu      720

uuacaccaau acuucaagac uguauaaaga auauagacag auacgcucuu gaugauuuaa      780

agucaaaagc auuauuuaau guuuuagcug caccuaccua ugauauaacu gaguauuuaa      840

gagcuacuaa agaaaaacca gaaaacacuc cuugguaugg uaaaauagau ggguuuauaa      900

augaacuuaa aaaguuagcu cuuuauggaa aaauaaauga uaauaacucu uggauaauag      960

auaacgguau auaucauaua gcaccuuuag ggaaguuaca uagcaauaau aaaauaggaa     1020

uagaaacuuu aacagagguu augaaaguuu auccuuauuu aaguaugcaa cauuuacaau     1080

cagcagauca aauuaagcgu cauuaugauu caaaagaugc ugaaggaaac aaaauaccuu     1140

uagauaaguu uaaaaaggaa ggaaaagaaa aauacugucc aaaaacuuau acauuugaug     1200

auggaaaagu aauaauaaaa gcuggugcua gaguagaaga agaaaaaguu aaaagacuau     1260

acugggcauc aaaggaaguu aacucucaau ucuuuagagu auacggaaua gacaaaccau     1320

uagaagaagg uaauccagau gauauauuaa caaugguuau cuacaacagu cccgaagaau     1380

auaaacucaa uaguguucua uacggauaug auacuaauaa uggugguaug uauauagagc     1440

cagaaggaac uuucuucacc uaugaaagag aagcucaaga aagcacauac acauuagaag     1500

aauuauuuag acaugaauau acacauuauu ugcaaggaag auaugcaguu ccaggacaau     1560

ggggaagaac aaaacuuuau gacaaugaua gauuaacuug guaugaagaa gguggagcag     1620

aauuauuugc agguucuacu agaacuucug gaauauuacc aagaaagagu auaguaucaa     1680

auauucauaa uacaacaaga aauaauagau auaagcuuuc agacacugua cauucuaaau     1740

auggugcuag uuuugaauuc uauaauuaug cauguauguu uauggauuau auguauaaua     1800

aagauauggg uauauuaaau aaacuaaaug aucuugcaaa aaauaaugau guugauggau     1860

augauaauua uauuagagau uuaaguucua auuaugcuuu aaaugauaaa uaucaagauc     1920

auaugcagga gcgcauagau aauuaugaaa auuuaacagu gccuuuugua gcugaugauu     1980

auuuaguaag gcaugcuuau aagaacccua augaaauuua uucugaaaua ucugaaguag     2040

caaaauuaaa ggaugcuaag agugaaguua agaaaucaca auauuuuagu accuuuacuu     2100

ugagagguag uuacacaggu ggagcaucua aggggaaauu agaagaucaa aaagcaauga     2160

auaaguuuau agaugauuca cuuaagaaau uagauacgua uucuuggagu ggguauaaaa     2220

cuuuaacugc uuauuucacu aauuauaaag uugacucuuc aaauagaguu acuuaugaug     2280

uaguauucca cggauauuua ccaaacgaag gugauuccaa aaauucauua ccuuauggca     2340

agaucaaugg aacuuacaag ggaacagaga aagaaaaaau caaauucucu agugaaggcu     2400

cuuucgaucc agaugguaaa auaguuucuu augaauggga uuucggagau gguaauaaga     2460

guaaugagga aaauccagag cauucauaug acaagguagg aacuuauaca gugaaauuaa     2520

aaguuacuga ugacaaggga gaaucuucag uaucuacuac uacugcagaa auaaaggauc     2580

uuucagaaaa uaaacuucca guuauauaua ugcauguacc uaaauccgga gccuuaaauc     2640

aaaaaguugu uuucuaugga aaaggaacau augacccaga uggaucuauc gcaggauauc     2700

aaugggacuu uggugaugga agugauuuua gcagugaaca aaacccaagc cauguauaua     2760

cuaaaaaagg ugaauauacu guaacauuaa gaguaaugga uaguagugga caaaugagug     2820

aaaaaacuau gaagauuaag auuacagauc cgguauaucc aauaggcacu gaaaaagaac     2880

caaauaacag uaaagaaacu gcaagugguc caauaguacc agguauaccu guuaguggaa     2940

ccauagaaaa uacaagugau caagauuauu ucuauuuuga uguuauaaca ccaggagaag     3000

uaaaaauaga uauaaauaaa uuaggguacg gaggagcuac uuggguagua uaugaugaaa     3060

auaauaaugc aguaucuuau gccacugaug augggcaaaa uuuaagugga aaguuuaagg     3120

cagauaaacc agguagauau uacauccauc uuuacauguu uaaugguagu uauaugccau     3180

auagaauuaa uauagaaggu ucaguaggaa gauaaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  3815
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (wt)

<400>  3815
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc caugaaaagg aaauguuuau cuaaaaggcu uauguuagcu auaacaaugg      180

cuacaauauu uacagugaac aguacauuac caauuuaugc agcuguagau aaaaauaaug      240

caacagcagc uagaaggcgg cgcaagagag uacaaaauga aaguaagagg uauacaguau      300

cauauuuaaa gacuuuaaau uauuaugacu uaguagauuu gcuuguuaag acugaaauug      360

agaauuuacc agaccuuuuu caguauaguu cagaugcaaa agaguucuau ggaaauaaaa      420

cucguaugag cuuuaucaug gaugaaauug guagaagggc accucaguau acagagauag      480

aucauaaagg uauuccuacu uuaguagaag uuguaagagc uggauuuuac uuaggauucc      540

auaacaagga auugaaugaa auaaacaaga ggucuuuuaa agaaagggua auaccuucua      600

uauuagcaau ucaaaaaaau ccuaauuuua aacuagguac ugaaguucaa gauaaaauag      660

uaucugcaac aggacuuuua gcugguaaug aaacagcgcc uccagaaguu guaaauaauu      720

uuacaccaau acuucaagac uguauaaaga auauagacag auacgcucuu gaugauuuaa      780

agucaaaagc auuauuuaau guuuuagcug caccuaccua ugauauaacu gaguauuuaa      840

gagcuacuaa agaaaaacca gaaaacacuc cuugguaugg uaaaauagau ggguuuauaa      900

augaacuuaa aaaguuagcu cuuuauggaa aaauaaauga uaauaacucu uggauaauag      960

auaacgguau auaucauaua gcaccuuuag ggaaguuaca uagcaauaau aaaauaggaa     1020

uagaaacuuu aacagagguu augaaaguuu auccuuauuu aaguaugcaa cauuuacaau     1080

cagcagauca aauuaagcgu cauuaugauu caaaagaugc ugaaggaaac aaaauaccuu     1140

uagauaaguu uaaaaaggaa ggaaaagaaa aauacugucc aaaaacuuau acauuugaug     1200

auggaaaagu aauaauaaaa gcuggugcua gaguagaaga agaaaaaguu aaaagacuau     1260

acugggcauc aaaggaaguu aacucucaau ucuuuagagu auacggaaua gacaaaccau     1320

uagaagaagg uaauccagau gauauauuaa caaugguuau cuacaacagu cccgaagaau     1380

auaaacucaa uaguguucua uacggauaug auacuaauaa uggugguaug uauauagagc     1440

cagaaggaac uuucuucacc uaugaaagag aagcucaaga aagcacauac acauuagaag     1500

aauuauuuag acaugaauau acacauuauu ugcaaggaag auaugcaguu ccaggacaau     1560

ggggaagaac aaaacuuuau gacaaugaua gauuaacuug guaugaagaa gguggagcag     1620

aauuauuugc agguucuacu agaacuucug gaauauuacc aagaaagagu auaguaucaa     1680

auauucauaa uacaacaaga aauaauagau auaagcuguc agacacugua cauucuaaau     1740

auggugcuag uuuugaguuc uauaauuaug cauguauguu uauggauuau auguauaaua     1800

aagauauggg uauauuaaau aaacuaaaug aucuugcaaa aaauaaugau guugauggau     1860

augauaauua uauuagagau uuaaguucua auuaugcuuu aaaugauaaa uaucaagauc     1920

auaugcagga gcgcauagau aauuaugaaa auuuaacagu gccuuuugua gcugaugauu     1980

auuuaguaag gcaugcuuau aagaacccua augaaauuua uucugaaaua ucugaaguag     2040

caaaauuaaa ggaugcuaag agugaaguua agaaaucaca auauuuuagu accuuuacuu     2100

ugagagguag uuacacaggu ggagcaucua aggggaaauu agaagaucaa aaagcaauga     2160

auaaguuuau agaugauuca cuuaagaaau uagauacgua uucuuggagu ggguauaaaa     2220

cuuuaacugc uuauuucacu aauuauaaag uugacucuuc aaauagaguu acuuaugaug     2280

uaguauucca cggauauuua ccaaacgaag gugauuccaa aaauucauua ccuuauggca     2340

agaucaaugg aacuuacaag ggaacagaga aagaaaaaau caaauucucu agugaaggcu     2400

cuuucgaucc agaugguaaa auaguuucuu augaauggga uuucggagau gguaauaaga     2460

guaaugagga aaauccagag cauucauaug acaagguagg aacuuauaca gugaaauuaa     2520

aaguuacuga ugacaaggga gaaucuucag uaucuacuac uacugcagaa auaaaggauc     2580

uuucagaaaa uaaacuucca guuauauaua ugcauguacc uaaauccgga gccuuaaauc     2640

aaaaaguugu uuucuaugga aaaggaacau augacccaga uggaucuauc gcaggauauc     2700

aaugggacuu uggugaugga agugauuuua gcagugaaca aaacccaagc cauguauaua     2760

cuaaaaaagg ugaauauacu guaacauuaa gaguaaugga uaguagugga caaaugagug     2820

aaaaaacuau gaagauuaag auuacagauc cgguauaucc aauaggcacu gaaaaagaac     2880

caaauaacag uaaagaaacu gcaagugguc caauaguacc agguauaccu guuaguggaa     2940

ccauagaaaa uacaagugau caagauuauu ucuauuuuga uguuauaaca ccaggagaag     3000

uaaaaauaga uauaaauaaa uuaggguacg gaggagcuac uuggguagua uaugaugaaa     3060

auaauaaugc aguaucuuau gccacugaug augggcaaaa uuuaagugga aaguuuaagg     3120

cagauaaacc agguagauau uacauccauc uuuacauguu uaaugguagu uauaugccau     3180

auagaauuaa uauagaaggu ucaguaggaa gauaaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  3816
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (wt)

<400>  3816
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuauuugc cugccuccug ggagcagcuu      120

uugccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc uuugaagugg uaccagagca uaaggccacc guacccuucc uaugguuacg      240

agcccauggg uggauggcug caccaccaaa ucauccccgu gcugucccaa cagcaccccc      300

cgacucacac ccugcagccu caucaccaca ucccaguggu gccagcucag cagcccguga      360

ucccccagca accaaugaug cccguuccug gccaacacuc caugacucca auccaacacc      420

accagccaaa ccucccuccg cccgcccagc agcccuacca gccccagccu guucagccac      480

agccucacca gcccaugcag ccccagccac cugugcaccc caugcagccc cugccgccac      540

agccaccucu gccuccgaug uuccccaugc agccccugcc ucccaugcuu ccugaucuga      600

cucuggaagc uuggccauca acagacaaga ccaagcggga ggaaguggau uaaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  3817
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (wt)

<400>  3817
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuauuugc cugccuccug ggagcagcuu      120

uugccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc uuugaagugg uaccagagca uaaggccacc guacccuucc uaugguuacg      240

agcccauggg uggauggcug caccaccaaa ucauccccgu gcugucccaa cagcaccccc      300

cgacucacac ccugcagccu caucaccaca ucccaguggu gccagcucag cagcccguga      360

ucccccagca accaaugaug cccguuccug gccaacacuc caugacucca auccaacacc      420

accagccaaa ccucccuccg cccgcccagc agcccuacca gccccagccu guucagccac      480

agccucacca gcccaugcag ccccagccac cugugcaccc caugcagccc cugccgccac      540

agccaccucu gccuccgaug uuccccaugc agccccugcc ucccaugcuu ccugaucuga      600

cucuggaagc auggccauca acagacaaga ccaagcggga ggaaguggau uaaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  3818
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (wt)

<400>  3818
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccuuugaagu gguaccagag cauaaggcca ccguacccuu      180

ccuaugguua cgagcccaug gguggauggu aaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  3819
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (wt)

<400>  3819
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccuuugaagu gguaccagag cauaaggcca ccucccaugc      180

uuccugaucu gacucuggaa gcuuggccau caacagacaa gaccaagcgg gaggaagugg      240

auuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  3820
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (wt)

<400>  3820
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccuuugaagu gguaccagag cauaaggcca ccucccaugc      180

uuccugaucu gacucuggaa gcauggccau caacagacaa gaccaagcgg gaggaagugg      240

auuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  3821
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (wt)

<400>  3821
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg cgccccgaac ccucguccug cuacucucgg      120

gggcucuggc ccugacccag accugggcga ugccucuacc accucauccu gggcacccug      180

guuauaucaa cuucagcuau gaggugcuua ccccuuugaa gugguaccag agcauaaggc      240

caccguaccc uuccuauggu uacgagccca uggguggaug guaaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  3822
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (wt)

<400>  3822
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg cgccccgaac ccucguccug cuacucucgg      120

gggcucuggc ccugacccag accugggcga ugccucuacc accucauccu gggcacccug      180

guuauaucaa cuucagcuau gaggugcuua ccccuuugaa gugguaccag agcauaaggc      240

caccucccau gcuuccugau cugacucugg aagcauggcc aucaacagac aagaccaagc      300

gggaggaagu ggauuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  3823
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (wt)

<400>  3823
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc cugccuugug ggagcagcuu      120

uugccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcucacccc uuugaagugg uaccagagca ugauaagacc accauacucu uccuaugguu      240

acgagcccau ggguggaugg cugcaccacc aaaucauccc cguggugucc caacagcacc      300

cccugacuca cacccugcag ucucaucacc acaucccagu ggugccagcu cagcagccca      360

ggguccgcca gcaagcacug augccuguuc cuggccagca auccaugacu ccaacccaac      420

accaucagcc aaaccucccu cugccugccc agcagcccuu ccagccccag ccuguucagc      480

cacagccuca ccagcccaug cagccccagc caccugugca acccaugcag ccccugcugc      540

cacagccacc ucugccucca auguuccccc ugcggccccu gccccccaua cuuccugauc      600

ugcaucugga agcuuggcca gcaacagaca agaccaagca ggaggaagug gauuaaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  3824
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (wt)

<400>  3824
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc cugccuugug ggagcagcuu      120

uugccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcucacccc uuugaagugg uaccagagca ugauaagacc accauacucu uccuaugguu      240

acgagcccau ggguggaugg cugcaccacc aaaucauccc cguggugucc caacagcacc      300

cccugacuca cacccugcag ucucaucacc acaucccagu ggugccagcu cagcagccca      360

ggguccgcca gcaagcacug augccuguuc cuggccagca auccaugacu ccaacccaac      420

accaucagcc aaaccucccu cugccugccc agcagcccuu ccagccccag ccuguucagc      480

cacagccuca ccagcccaug cagccccagc caccugugca acccaugcag ccccugcugc      540

cacagccacc ucugccucca auguuccccc ugcggccccu gccccccaua cuuccugauc      600

ugcaucugga agcauggcca gcaacagaca agaccaagca ggaggaagug gauuaaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  3825
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (wt)

<400>  3825
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcucacc ccuuugaagu gguaccagag caugauaaga ccaccauacu      180

cuuccuaugg uuacgagccc auggguggau gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  3826
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (wt)

<400>  3826
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcucacc ccuuugaagu gguaccagag caugauaaga ccacccccca      180

uacuuccuga ucugcaucug gaagcuuggc cagcaacaga caagaccaag caggaggaag      240

uggauuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  3827
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (wt)

<400>  3827
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcucacc ccuuugaagu gguaccagag caugauaaga ccacccccca      180

uacuuccuga ucugcaucug gaagcauggc cagcaacaga caagaccaag caggaggaag      240

uggauuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  3828
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (wt)

<400>  3828
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg cgccccgaac ccucguccug cuacucucgg      120

gggcucuggc ccugacccag accugggcga ugccucuacc accucauccu gggcacccug      180

guuauaucaa cuucagcuau gaggugcuca ccccuuugaa gugguaccag agcaugauaa      240

gaccaccaua cucuuccuau gguuacgagc ccaugggugg augguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  3829
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (wt)

<400>  3829
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg cgccccgaac ccucguccug cuacucucgg      120

gggcucuggc ccugacccag accugggcga ugccucuacc accucauccu gggcacccug      180

guuauaucaa cuucagcuau gaggugcuca ccccuuugaa gugguaccag agcaugauaa      240

gaccaccccc cauacuuccu gaucugcauc uggaagcaug gccagcaaca gacaagacca      300

agcaggagga aguggauuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  3830
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (wt)

<400>  3830
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccguacacu uccuaugggu      240

acgaacccau ggguggaugg cugcaccacc aaaucauacc cguggugucg cagcagacuc      300

cccagaguca ugcccuucag ccucaucacc acauccccau ggugccagcu caacagcccg      360

ggauccccca gcagccaaug augccacuuc cuggccaaca cuccaugacu ccaacccaac      420

accaccagcc aaaccucccu cugcccgccc agcagcccuu ccagccccag cccguccagc      480

cccagccuca ccagccccug cagccccagu cacccaugca ccccauccag cccuugcugc      540

cacagccacc ucugccuccg auguucucca ugcagucucu gcuuccugac cugccucugg      600

aagcuuggcc agcaacagac aagaccaagc gggaggaagu ggauuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  3831
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (wt)

<400>  3831
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccguacacu uccuaugggu      240

acgaacccau ggguggaugg cugcaccacc aaaucauacc cguggugucg cagcagacuc      300

cccagaguca ugcccuucag ccucaucacc acauccccau ggugccagcu caacagcccg      360

ggauccccca gcagccaaug augccacuuc cuggccaaca cuccaugacu ccaacccaac      420

accaccagcc aaaccucccu cugcccgccc agcagcccuu ccagccccag cccguccagc      480

cccagccuca ccagccccug cagccccagu cacccaugca ccccauccag cccuugcugc      540

cacagccacc ucugccuccg auguucucca ugcagucucu gcuuccugac cugccucugg      600

aagcauggcc agcaacagac aagaccaagc gggaggaagu ggauuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  3832
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (wt)

<400>  3832
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccucugaagu gguaccagaa caugauaaga cauccguaca      180

cuuccuaugg guacgaaccc auggguggau gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  3833
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (wt)

<400>  3833
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccucugaagu gguaccagaa caugauaaga cauccgucuc      180

ugcuuccuga ccugccucug gaagcuuggc cagcaacaga caagaccaag cgggaggaag      240

uggauuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  3834
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (wt)

<400>  3834
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccucugaagu gguaccagaa caugauaaga cauccgucuc      180

ugcuuccuga ccugccucug gaagcauggc cagcaacaga caagaccaag cgggaggaag      240

uggauuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  3835
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (wt)

<400>  3835
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg cgccccgaac ccucguccug cuacucucgg      120

gggcucuggc ccugacccag accugggcga ugccucuacc accucauccu gggcacccug      180

guuauaucaa cuucagcuau gaggugcuua ccccucugaa gugguaccag aacaugauaa      240

gacauccgua cacuuccuau ggguacgaac ccaugggugg augguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  3836
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (wt)

<400>  3836
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg cgccccgaac ccucguccug cuacucucgg      120

gggcucuggc ccugacccag accugggcga ugccucuacc accucauccu gggcacccug      180

guuauaucaa cuucagcuau gaggugcuua ccccucugaa gugguaccag aacaugauaa      240

gacauccguc ucugcuuccu gaccugccuc uggaagcaug gccagcaaca gacaagacca      300

agcgggagga aguggauuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  3837
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (wt)

<400>  3837
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuauauaa      180

gacauccgua cacuuccuau ggguacgaac ccaugggugg auggcugcac caccaaauca      240

uacccguggu gucgcagcag acuccccaga gucaugcccu ucagccucau caccacaucc      300

ccauggugcc agcucaacag cccgggaucc cccagcagcc aaugaugcca cuuccuggcc      360

aacacuccau gacuccaacc caacaccacc agccaaaccu cccucugccc gcccagcagc      420

ccuuccagcc ccagcccguc cagccccagc cucaccagcc ccugcagccc cagucaccca      480

ugcaccccau ccagcccuug cugccacagc caccucugcc uccgauguuc uccaugcagu      540

cucugcuucc ugaccugccu cuggaagcuu ggccagcaac agacaagacc aagcgggagg      600

aaguggauua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  3838
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (wt)

<400>  3838
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuucuuugc cugccuuuug ggagcauccc      120

uugcuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccguacacu uccuaugggu      240

acgaacccau ggguggaugg cugcaccacc aaaucauacc cguggugucg cagcagacuc      300

cccagaguca ugcccuucag ccucaucacc acauccccau ggugccagcu caacagcccg      360

ggauccccca gcagccaaug augccacuuc cuggccaaca cuccaugacu ccaacccaac      420

accaccagcc aaaccucccu cugcccgccc agcagcccuu ccagccccag cccguccagc      480

cccagccuca ccagccccug cagccccagu cacccaugca ccccauccag cccuugcugc      540

cacagccacc ucugccuccg auguucucca ugcagucucu gcuuccugac cugccucugg      600

aagcuuggcc agcaacagac aagaccaagc gggaggaagu ggauuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  3839
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (wt)

<400>  3839
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccgucucug cuuccugacc      240

ugccucugga agcuuggcca gcaacagaca agaccaagcg ggaggaagug gauuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  3840
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (wt)

<400>  3840
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

acuuauacuu ggaggcuauc cguauugaca ggacugcauu cgugcuuacc ccucugaagu      240

gguaccagaa caugauaaga cauccguaca cuuccuaugg uuacgaaccc auggguggau      300

ggcugcacca ccaaaucauu cccguggugu cgcagcagac uccccagagu caugcccuuc      360

agccucauca ccacaucccc auggugccag cucaacagcc cgggaucccc cagcagccaa      420

ugaugccacu uccuggccaa cacuccauga cuccaaccca acaccaccag ccaaaccucc      480

cucugcccgc ccagcagccc uuccagcccc agcccgucca gccccagccu caccagcccc      540

ugcagcccca gucacccaug caccccaucc agcccuugcu gccacagcca ccucugccuc      600

cgauguucuc caugcagucu cugcuuccug accugccucu ggaagcuugg ccagcaacag      660

acaagaccaa gcgggaggaa guggauuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  3841
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (wt)

<400>  3841
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccgacuccc cagagucaug      240

cccuucagcc ucaucaccac auccccaugg ugccagcuca acagcccggg aucccccagc      300

agccaaugau gccacuuccu ggccaacacu ccaugacucc aacccaacac caccagccaa      360

accucccucu gcccgcccag cagcccuucc agccccagcc cguccagccc cagccucacc      420

agccccugca gccccaguca cccaugcacc ccauccagcc cuugcugcca cagccaccuc      480

ugccuccgau guucuccaug cagucucugc uuccugaccu gccucuggaa gcuuggccag      540

caacagacaa gaccaagcgg gaggaagugg auuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  3842
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (wt)

<400>  3842
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccucugaagu gguaccagaa caugauaaga cauccguaca      180

cuuccuaugg guacgaaccc auggguggau ggcugcacca ccaaaucaua cccguggugu      240

cgcagcagac uccccagagu caugcccuuc agccucauca ccacaucccc auggugccag      300

cucaacagcc cgggaucccc cagcagccaa ugaugccacu uccuggccaa cacuccauga      360

cuccaaccca acaccaccag ccaaaccucc cucugcccgc ccagcagccc uuccagcccc      420

agcccgucca gccccagccu caccagcccc ugcagcccca gucacccaug caccccaucc      480

agcccuugcu gccacagcca ccucugccuc cgauguucuc caugcagucu cugcuuccug      540

accugccucu ggaagcuugg ccagcaacag acaagaccaa gcgggaggaa guggauuaag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  3843
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (wt)

<400>  3843
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg cccgccugcc gcugcugcuc gggcugcugc      120

ugcucccgcg ucccggccgg ccgcuggacu uggccgacua caccuaugac cuggcggagg      180

aggacgacuc ggagccccuc aacuacaaag accccugcaa ggcggcugcc uuucuugggg      240

acauugcccu ggacgaagag gaccugaggg ccuuccaggu acagcaggcu guggaucuca      300

gacggcacac agcucguaag uccuccauca aagcugcagu uccaggaaac acuucuaccc      360

ccagcugcca gagcaccaac gggcagccuc agaggggagc cugugggaga uggagaggua      420

gaucccguag ccggcgggcg gcgacguccc gaccagagcg uguguggccc gaugggguca      480

uccccuuugu cauuggggga aacuucacug guagccagag ggcagucuuc cggcaggcca      540

ugaggcacug ggagaagcac accuguguca ccuuccugga gcgcacugac gaggacagcu      600

auauuguguu caccuaucga ccuugcgggu gcugcuccua cgugggucgc cgcggcgggg      660

gcccccaggc caucuccauc ggcaagaacu gugacaaguu cggcauugug guccacgagc      720

ugggccacgu cgucggcuuc uggcacgaac acacucggcc agaccgggac cgccacguuu      780

ccaucguucg ugagaacauc cagccagggc aggaguauaa cuuccugaag auggagccuc      840

aggaggugga gucccugggg gagaccuaug acuucgacag caucaugcau uacgcucgga      900

acacauucuc caggggcauc uuccuggaua ccauuguccc caaguaugag gugaacgggg      960

ugaaaccucc cauuggccaa aggacacggc ucagcaaggg ggacauugcc caagcccgca     1020

agcuuuacaa gugcccagcc uguggagaga cccugcaaga cagcacaggc aacuucuccu     1080

ccccugaaua ccccaauggc uacucugcuc acaugcacug cguguggcgc aucucuguca     1140

cacccgggga gaagaucauc cugaacuuca cgucccugga ccuguaccgc agccgccugu     1200

gcugguacga cuauguggag guccgagaug gcuucuggag gaaggcgccc cuccgaggcc     1260

gcuucugcgg guccaaacuc ccugagccua ucgucuccac ugacagccgc cucuggguug     1320

aauuccgcag cagcagcaau uggguuggaa agggcuucuu ugcagucuac gaagccaucu     1380

gcggggguga ugugaaaaag gacuauggcc acauucaauc gcccaacuac ccagacgauu     1440

accggcccag caaagucugc aucuggcgga uccagguguc ugagggcuuc cacgugggcc     1500

ucacauucca guccuuugag auugagcgcc acgacagcug ugccuacgac uaucuggagg     1560

ugcgcgacgg gcacagugag agcagcaccc ucaucgggcg cuacuguggc uaugagaagc     1620

cugaugacau caagagcacg uccagccgcc ucuggcucaa guucgucucu gacgggucca     1680

uuaacaaagc gggcuuugcc gucaacuuuu ucaaagaggu ggacgagugc ucucggccca     1740

accgcggggg cugugagcag cggugccuca acacccuggg cagcuacaag ugcagcugug     1800

accccgggua cgagcuggcc ccagacaagc gccgcuguga ggcugcuugu ggcggauucc     1860

ucaccaagcu caacggcucc aucaccagcc cgggcuggcc caaggaguac ccccccaaca     1920

agaacugcau cuggcagcug guggccccca cccaguaccg caucucccug caguuugacu     1980

ucuuugagac agagggcaau gaugugugca aguacgacuu cguggaggug cgcaguggac     2040

ucacagcuga cuccaagcug cauggcaagu ucugugguuc ugagaagccc gaggucauca     2100

ccucccagua caacaacaug cgcguggagu ucaaguccga caacaccgug uccaaaaagg     2160

gcuucaaggc ccacuucuuc ucagacaagg acgagugcuc caaggauaac ggcggcugcc     2220

agcaggacug cgucaacacg uucggcaguu augagugcca augccgcagu ggcuucgucc     2280

uccaugacaa caagcacgac ugcaaagaag ccggcuguga ccacaaggug acauccacca     2340

gugguaccau caccagcccc aacuggccug acaaguaucc cagcaagaag gagugcacgu     2400

gggccaucuc cagcaccccc gggcaccggg ucaagcugac cuucauggag auggacaucg     2460

agucccagcc ugagugugcc uacgaccacc uagagguguu cgacgggcga gacgccaagg     2520

cccccguccu cggccgcuuc ugugggagca agaagcccga gcccguccug gccacaggca     2580

gccgcauguu ccugcgcuuc uacucagaua acucggucca gcgaaagggc uuccaggccu     2640

cccacgccac agagugcggg ggccagguac gggcagacgu gaagaccaag gaccuuuacu     2700

cccacgccca guuuggcgac aacaacuacc cugggggugu ggacugugag ugggucauug     2760

uggccgagga aggcuacggc guggagcucg uguuccagac cuuugaggug gaggaggaga     2820

ccgacugcgg cuaugacuac auggagcucu ucgacggcua cgacagcaca gcccccaggc     2880

uggggcgcua cuguggcuca gggccuccug aggaggugua cucggcggga gauucugucc     2940

uggugaaguu ccacucggau gacaccauca ccaaaaaagg uuuccaccug cgauacacca     3000

gcaccaaguu ccaggacaca cuccacagca ggaagugagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  3844
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (wt)

<400>  3844
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggga cccgcugucu ucuagcguug cugcuucccc      120

agguccuccu gggcggcgcg gcuggccucg uuccggagcu gggccgcagg aaguucgcgg      180

cggcgucguc gggccgcccc ucaucccagc ccucugacga gguccugagc gaguucgagu      240

ugcggcugcu cagcauguuc ggccugaaac agagacccac ccccagcagg gacgccgugg      300

ugccccccua caugcuagac cuguaucgca ggcacucagg ucagccgggc ucacccgccc      360

cagaccaccg guuggagagg gcagccagcc gagccaacac ugugcgcagc uuccaccaug      420

aagaaucuuu ggaagaacua ccagaaacga gugggaaaac aacccggaga uucuucuuua      480

auuuaaguuc uauccccacg gaggaguuua ucaccucagc agagcuucag guuuuccgag      540

aacagaugca agaugcuuua ggaaacaaua gcaguuucca ucaccgaauu aauauuuaug      600

aaaucauaaa accugcaaca gccaacucga aauuccccgu gaccagacuu uuggacacca      660

gguuggugaa ucagaaugca agcagguggg aaaguuuuga ugucaccccc gcugugaugc      720

gguggacugc acagggacac gccaaccaug gauucguggu ggaaguggcc cacuuggagg      780

agaaacaagg ugucuccaag agacauguua ggauaagcag gucuuugcac caagaugaac      840

acagcugguc acagauaagg ccauugcuag uaacuuuugg ccaugaugga aaagggcauc      900

cucuccacaa aagagaaaaa cgucaagcca aacacaaaca gcggaaacgc cuuaagucca      960

gcuguaagag acacccuuug uacguggacu ucagugacgu gggguggaau gacuggauug     1020

uggcuccccc gggguaucac gccuuuuacu gccacggaga augcccuuuu ccucuggcug     1080

aucaucugaa cuccacuaau caugccauug uucagacguu ggucaacucu guuaacucua     1140

agauuccuaa ggcaugcugu gucccgacag aacucagugc uaucucgaug cuguaccuug     1200

acgagaauga aaagguugua uuaaagaacu aucaggacau gguuguggag gguugugggu     1260

gucgcuaggg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  3845
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (wt)

<400>  3845
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auuccuggua accgaaugcu gauggucguu uuauuaugcc      120

aaguccugcu aggaggcgcg agccaugcua guuugauacc ugagacgggg aagaaaaaag      180

ucgccgagau ucagggccac gcgggaggac gccgcucagg gcagagccau gagcuccugc      240

gggacuucga ggcgacacuu cugcagaugu uugggcugcg ccgccgcccg cagccuagca      300

agagugccgu cauuccggac uacaugcggg aucuuuaccg gcuucagucu ggggaggagg      360

aggaagagca gauccacagc acuggucuug aguauccuga gcgcccggcc agccgggcca      420

acaccgugag gagcuuccac cacgaagaac aucuggagaa caucccaggg accagugaaa      480

acucugcuuu ucguuuccuc uuuaaccuca gcagcauccc ugagaacgag gugaucuccu      540

cugcagagcu ucggcucuuc cgggagcagg uggaccaggg cccugauugg gaaaggggcu      600

uccaccguau aaacauuuau gagguuauga agcccccagc agaaguggug ccugggcacc      660

ucaucacacg acuacuggac acgagacugg uccaccacaa ugugacacgg ugggaaacuu      720

uugaugugag cccugcgguc cuucgcugga cccgggagaa gcagccaaac uaugggcuag      780

ccauugaggu gacucaccuc caucagacuc ggacccacca gggccagcau gucaggauua      840

gccgaucguu accucaaggg agugggaauu gggcccagcu ccggccccuc cuggucaccu      900

uuggccauga uggccggggc caugccuuga cccgacgccg gagggccaag cguagcccua      960

agcaucacuc acagcgggcc aggaagaaga auaagaacug ccggcgccac ucgcucuaug     1020

uggacuucag cgaugugggc uggaaugacu ggauuguggc cccaccaggc uaccaggccu     1080

ucuacugcca uggggacugc cccuuuccac uggcugacca ccucaacuca accaaccaug     1140

ccauugugca gacccugguc aauucuguca auuccaguau ccccaaagcc uguugugugc     1200

ccacugaacu gagugccauc uccaugcugu accuggauga guaugauaag gugguacuga     1260

aaaauuauca ggagauggua guagagggau gugggugccg cugaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  3846
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (wt)

<400>  3846
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggggcugg ggcggagggc gcaguggcug ugcugguggu      120

gggggcugcu gugcagcugc ugcgggcccc cgccgcugcg gccgcccuug cccgcugccg      180

cggccgccgc cgccgggggg cagcugcugg gggacggcgg gagccccggc cgcacggagc      240

agccgccgcc gucgccgcag uccuccucgg gcuuccugua ccggcggcuc aagacgcagg      300

agaagcggga gaugcagaag gagaucuugu cggugcuggg gcucccgcac cggccccggc      360

cccugcacgg ccuccaacag ccgcagcccc cggcgcuccg gcagcaggag gagcagcagc      420

agcagcagca gcugccucgc ggagagcccc cucccgggcg acugaagucc gcgccccucu      480

ucaugcugga ucuguacaac gcccuguccg ccgacaacga cgaggacggg gcgucggagg      540

gggagaggca gcaguccugg ccccacgaag cagccagcuc gucccagcgu cggcagccgc      600

ccccgggcgc cgcgcacccg cucaaccgca agagccuucu ggcccccgga ucuggcagcg      660

gcggcgcguc cccacugacc agcgcgcagg acagcgccuu ccucaacgac gcggacaugg      720

ucaugagcuu ugugaaccug guggaguacg acaaggaguu cuccccucgu cagcgacacc      780

acaaagaguu caaguucaac uuaucccaga uuccugaggg ugagguggug acggcugcag      840

aauuccgcau cuacaaggac uguguuaugg ggaguuuuaa aaaccaaacu uuucuuauca      900

gcauuuauca agucuuacag gagcaucagc acagagacuc ugaccuguuu uuguuggaca      960

cccguguagu augggccuca gaagaaggcu ggcuggaauu ugacaucacg gccacuagca     1020

aucugugggu ugugacucca cagcauaaca uggggcuuca gcugagcgug gugacaaggg     1080

auggagucca cguccacccc cgagccgcag gccugguggg cagagacggc ccuuacgaca     1140

agcagcccuu caugguggcu uucuucaaag ugagugaggu gcacgugcgc accaccaggu     1200

cagccuccag ccggcgccga caacagaguc guaaucgcuc uacccagucc caggacgugg     1260

cgcgggucuc cagugcuuca gauuacaaca gcagugaauu gaaaacagcc ugcaggaagc     1320

augagcugua ugugaguuuc caagaccugg gauggcagga cuggaucauu gcacccaagg     1380

gcuaugcugc caauuacugu gauggagaau gcuccuuccc acucaacgca cacaugaaug     1440

caaccaacca cgcgauugug cagaccuugg uucaccuuau gaaccccgag uaugucccca     1500

aaccgugcug ugcgccaacu aagcuaaaug ccaucucggu ucuuuacuuu gaugacaacu     1560

ccaaugucau ucugaaaaaa uacaggaaua ugguuguaag agcuugugga ugccacuaag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  3847
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (wt)

<400>  3847
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugcgcu cacugcgagc ugcggcgccg cacagcuucg      120

uggcgcucug ggcaccccug uuccugcugc gcuccgcccu ggccgacuuc agccuggaca      180

acgaggugca cucgagcuuc auccaccggc gccuccgcag ccaggagcgg cgggagaugc      240

agcgcgagau ccucuccauu uugggcuugc cccaccgccc gcgcccgcac cuccagggca      300

agcacaacuc ggcacccaug uucaugcugg accuguacaa cgccauggcg guggaggagg      360

gcggcgggcc cggcggccag ggcuucuccu accccuacaa ggccgucuuc aguacccagg      420

gccccccucu ggccagccug caagauagcc auuuccucac cgacgccgac auggucauga      480

gcuucgucaa ccucguggaa caugacaagg aauucuucca cccacgcuac caccaucgag      540

aguuccgguu ugaucuuucc aagaucccag aaggggaagc ugucacggca gccgaauucc      600

ggaucuacaa ggacuacauc cgggaacgcu ucgacaauga gacguuccgg aucagcguuu      660

aucaggugcu ccaggagcac uugggcaggg aaucggaucu cuuccugcuc gacagccgua      720

cccucugggc cucggaggag ggcuggcugg uguuugacau cacagccacc agcaaccacu      780

ggguggucaa uccgcggcac aaccugggcc ugcagcucuc gguggagacg cuggaugggc      840

agagcaucaa ccccaaguug gcgggccuga uugggcggca cgggccccag aacaagcagc      900

ccuucauggu ggcuuucuuc aaggccacgg agguccacuu ccgcagcauc cgguccacgg      960

ggagcaaaca gcgcagccag aaccgcucca agacgcccaa gaaccaggaa gcccugcgga     1020

uggccaacgu ggcagagaac agcagcagcg accagaggca ggccuguaag aagcacgagc     1080

uguaugucag cuuccgagac cugggcuggc aggacuggau caucgcgccu gaaggcuacg     1140

ccgccuacua cugugagggg gagugugccu ucccucugaa cuccuacaug aacgccacca     1200

accacgccau cgugcagacg cugguccacu ucaucaaccc ggaaacggug cccaagcccu     1260

gcugugcgcc cacgcagcuc aaugccaucu ccguccucua cuucgaugac agcuccaacg     1320

ucauccugaa gaaauacaga aacauggugg uccgggccug uggcugccac uagggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  3848
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (wt)

<400>  3848
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagccucug cagcacuucu gugucugcug cucacagcag      120

cugcuuucag cccccagggg cuugcucagc caguugggau uaauacuuca acuaccugcu      180

gcuacagauu uaucaauaag aaaaucccua agcagaggcu ggagagcuac agaaggacca      240

ccaguagcca cuguccccgg gaagcuguaa ucuucaagac caaacuggac aaggagaucu      300

gugcugaccc cacacagaag uggguccagg acuuuaugaa gcaccuggac aagaaaaccc      360

aaacuccaaa gcuuugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  3849
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (wt)

<400>  3849
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucacuc uuaucauucu guugccagua guuucaaaau      120

uuaguuuugu uagucucuca gcaccgcagc acuggagcug uccugaaggu acucucgcag      180

gaaaugggaa uucuacuugu guggguccug cacccuucuu aauuuucucc cauggaaaua      240

guaucuuuag gauugacaca gaaggaacca auuaugagca auugguggug gaugcuggug      300

ucucagugau cauggauuuu cauuauaaug agaaaagaau cuauugggug gauuuagaaa      360

gacaacuuuu gcaaagaguu uuucugaaug ggucaaggca agagagagua uguaauauag      420

agaaaaaugu uucuggaaug gcaauaaauu ggauaaauga agaaguuauu uggucaaauc      480

aacaggaagg aaucauuaca guaacagaua ugaaaggaaa uaauucccac auucuuuuaa      540

gugcuuuaaa auauccugca aauguagcag uugauccagu agaaagguuu auauuuuggu      600

cuucagaggu ggcuggaagc cuuuauagag cagaucucga ugguguggga gugaaggcuc      660

uguuggagac aucagagaaa auaacagcug ugucauugga ugugcuugau aagcggcugu      720

uuuggauuca guacaacaga gaaggaagca auucucuuau uugcuccugu gauuaugaug      780

gagguucugu ccacauuagu aaacauccaa cacagcauaa uuuguuugca augucccuuu      840

uuggugaccg uaucuucuau ucaacaugga aaaugaagac aauuuggaua gccaacaaac      900

acacuggaaa ggacaugguu agaauuaacc uccauucauc auuuguacca cuuggugaac      960

ugaaaguagu gcauccacuu gcacaaccca aggcagaaga ugacacuugg gagccugagc     1020

agaaacuuug caaauugagg aaaggaaacu gcagcagcac uguguguggg caagaccucc     1080

agucacacuu gugcaugugu gcagagggau acgcccuaag ucgagaccgg aaguacugug     1140

aagauguuaa ugaaugugcu uuuuggaauc auggcuguac ucuugggugu aaaaacaccc     1200

cuggauccua uuacugcacg ugcccuguag gauuuguucu gcuuccugau gggaaacgau     1260

gucaucaacu uguuuccugu ccacgcaaug ugucugaaug cagccaugac uguguucuga     1320

caucagaagg ucccuuaugu uucuguccug aaggcucagu gcuugagaga gaugggaaaa     1380

cauguagcgg uuguuccuca cccgauaaug guggauguag ccagcucugc guuccucuua     1440

gcccaguauc cugggaaugu gauugcuuuc cuggguauga ccuacaacug gaugaaaaaa     1500

gcugugcagc uucaggacca caaccauuuu ugcuguuugc caauucucaa gauauucgac     1560

acaugcauuu ugauggaaca gacuauggaa cucugcucag ccagcagaug ggaaugguuu     1620

augcccuaga ucaugacccu guggaaaaua agauauacuu ugcccauaca gcccugaagu     1680

ggauagagag agcuaauaug gaugguuccc agcgagaaag gcuuauugag gaaggaguag     1740

augugccaga aggucuugcu guggacugga uuggccguag auucuauugg acagacagag     1800

ggaaaucucu gauuggaagg agugauuuaa augggaaacg uuccaaaaua aucacuaagg     1860

agaacaucuc ucaaccacga ggaauugcug uucauccaau ggccaagaga uuauucugga     1920

cugauacagg gauuaaucca cgaauugaaa guucuucccu ccaaggccuu ggccgucugg     1980

uuauagccag cucugaucua aucuggccca guggaauaac gauugacuuc uuaacugaca     2040

aguuguacug gugcgaugcc aagcagucug ugauugaaau ggccaaucug gaugguucaa     2100

aacgccgaag acuuacccag aaugauguag gucacccauu ugcuguagca guguuugagg     2160

auuaugugug guucucagau ugggcuaugc caucaguaau gagaguaaac aagaggacug     2220

gcaaagauag aguacgucuc caaggcagca ugcugaagcc cucaucacug guugugguuc     2280

auccauuggc aaaaccagga gcagaucccu gcuuauauca aaacggaggc ugugaacaua     2340

uuugcaaaaa gaggcuugga acugcuuggu guucgugucg ugaagguuuu augaaagccu     2400

cagaugggaa aacgugucug gcucuggaug gucaucagcu guuggcaggu ggugaaguug     2460

aucuaaagaa ccaaguaaca ccauuggaca ucuuguccaa gacuagagug ucagaagaua     2520

acauuacaga aucucaacac augcuagugg cugaaaucau ggugucagau caagaugacu     2580

gugcuccugu gggaugcagc auguaugcuc gguguauuuc agagggagag gaugccacau     2640

gucaguguuu gaaaggauuu gcuggggaug gaaaacuaug uucugauaua gaugaaugug     2700

agaugggugu cccagugugc cccccugccu ccuccaagug caucaacacc gaaggugguu     2760

augucugccg gugcucagaa ggcuaccaag gagaugggau ucacugucuu gauauugaug     2820

agugccaacu gggggagcac agcuguggag agaaugccag cugcacaaau acagagggag     2880

gcuauaccug caugugugcu ggacgccugu cugaaccagg acugauuugc ccugacucua     2940

cuccaccccc ucaccucagg gaagaugacc accacuauuc cguaagaaau agugacucug     3000

aauguccccu gucccacgau ggguacugcc uccaugaugg ugugugcaug uauauugaag     3060

cauuggacaa guaugcaugc aacuguguug uuggcuacau cggggagcga ugucaguacc     3120

gagaccugaa guggugggaa cugcgccacg cuggccacgg gcagcagcag aaggucaucg     3180

ugguggcugu cugcguggug gugcuuguca ugcugcuccu ccugagccug uggggggccc     3240

acuacuacag gacucagaag cugcuaucga aaaacccaaa gaauccuuau gaggagucga     3300

gcagagaugu gaggagucgc aggccugcug acacugagga ugggaugucc ucuugcccuc     3360

aaccuugguu ugugguuaua aaagaacacc aagaccucaa gaaugggggu caaccagugg     3420

cuggugagga uggccaggca gcagaugggu caaugcaacc aacuucaugg aggcaggagc     3480

cccaguuaug uggaaugggc acagagcaag gcugcuggau uccaguaucc agugauaagg     3540

gcuccugucc ccagguaaug gagcgaagcu uucauaugcc cuccuauggg acacagaccc     3600

uugaaggggg ugucgagaag ccccauucuc uccuaucagc uaacccauua uggcaacaaa     3660

gggcccugga cccaccacac caaauggagc ugacucagug aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  3850
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (wt)

<400>  3850
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgcgggga ggaggaugga gaugcucugu gccggcaggg      120

ucccugcgcu gcugcucugc cuggguuucc aucuucuaca ggcaguccuc aguacaacug      180

ugauuccauc auguauccca ggagagucca gugauaacug cacagcuuua guucagacag      240

aagacaaucc acguguggcu caagugucaa uaacaaagug uagcucugac augaauggcu      300

auuguuugca uggacagugc aucuaucugg uggacaugag ucaaaacuac ugcaggugug      360

aaguggguua uacugguguc cgaugugaac acuucuuuuu aaccguccac caaccuuuaa      420

gcaaagaaua uguggcuuug accgugauuc uuauuauuuu guuucuuauc acagucgucg      480

guuccacaua uuauuucugc agaugguaca gaaaucgaaa aaguaaagaa ccaaagaagg      540

aauaugagag aguuaccuca ggggauccag aguugccgca agucugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  3851
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (wt)

<400>  3851
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcugaagggg aaaucaccac cuucacagcc cugaccgaga      120

aguuuaaucu gccuccaggg aauuacaaga agcccaaacu ccucuacugu agcaacgggg      180

gccacuuccu gaggauccuu ccggauggca caguggaugg gacaagggac aggagcgacc      240

agcacauuca gcugcagcuc agugcggaaa gcguggggga gguguauaua aagaguaccg      300

agacuggcca guacuuggcc auggacaccg acgggcuuuu auacggcuca cagacaccaa      360

augaggaaug uuuguuccug gaaaggcugg aggagaacca uuacaacacc uauauaucca      420

agaagcaugc agagaagaau ugguuuguug gccucaagaa gaaugggagc ugcaaacgcg      480

guccucggac ucacuauggc cagaaagcaa ucuuguuucu cccccugcca gucucuucug      540

auuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  3852
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (wt)

<400>  3852
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggugugg gggguggaga uguagaagau gugacgccgc      120

ggcccggcgg gugccagauu agcggacgcg gugcccgcgg uugcaacggg aucccgggcg      180

cugcagcuug ggaggcggcu cuccccaggc ggcguccgcg gagacaccca uccgugaacc      240

ccaggucccg ggccgccggc ucgccgcgca ccaggggccg gcggacagaa gagcggccga      300

gcggcucgag gcugggggac cgcgggcgcg gccgcgcgcu gccgggcggg aggcuggggg      360

gccggggccg gggccgugcc ccggagcggg ucggaggccg gggccggggc cgggggacgg      420

cggcuccccg cgcggcucca gcggcucggg gaucccggcc gggccccgca gggaccaugg      480

cagccgggag caucaccacg cugcccgccu ugcccgagga uggcggcagc ggcgccuucc      540

cgcccggcca cuucaaggac cccaagcggc uguacugcaa aaacgggggc uucuuccugc      600

gcauccaccc cgacggccga guugacgggg uccgggagaa gagcgacccu cacaucaagc      660

uacaacuuca agcagaagag agaggaguug ugucuaucaa aggagugugu gcuaaccguu      720

accuggcuau gaaggaagau ggaagauuac uggcuucuaa auguguuacg gaugaguguu      780

ucuuuuuuga acgauuggaa ucuaauaacu acaauacuua ccggucaagg aaauacacca      840

guugguaugu ggcacugaaa cgaacugggc aguauaaacu uggauccaaa acaggaccug      900

ggcagaaagc uauacuuuuu cuuccaaugu cugcuaagag cugaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  3853
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (wt)

<400>  3853
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uacugacaug gauccugcca acuuugcucu      120

acagaucaug cuuucacauu aucugucuag uggguacuau aucuuuagcu ugcaaugaca      180

ugacuccaga gcaaauggcu acaaauguga acuguuccag cccugagcga cacacaagaa      240

guuaugauua cauggaagga ggggauauaa gagugagaag acucuucugu cgaacacagu      300

gguaccugag gaucgauaaa agaggcaaag uaaaagggac ccaagagaug aagaauaauu      360

acaauaucau ggaaaucagg acaguggcag uuggaauugu ggcaaucaaa gggguggaaa      420

gugaauucua ucuugcaaug aacaaggaag gaaaacucua ugcaaagaaa gaaugcaaug      480

aagauuguaa cuucaaagaa cuaauucugg aaaaccauua caacacauau gcaucagcua      540

aauggacaca caacggaggg gaaauguuug uugccuuaaa ucaaaagggg auuccuguaa      600

gaggaaaaaa aacgaagaaa gaacaaaaaa cagcccacuu ucuuccuaug gcaauaacuu      660

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  3854
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (wt)

<400>  3854
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugcugc cgucgguggu gcugaagcuc uuucuggcug      120

caguucucuc ggcacuggug acuggcgaga gccuggagcg gcuucggaga gggcuagcug      180

cuggaaccag caacccggac ccucccacug uauccacgga ccagcugcua ccccuaggag      240

gcggccggga ccggaaaguc cgugacuugc aagaggcaga ucuggaccuu uugagaguca      300

cuuuauccuc caagccacaa gcacuggcca caccaaacaa ggaggagcac gggaaaagaa      360

agaagaaagg caaggggcua gggaagaaga gggacccaug ucuucggaaa uacaaggacu      420

ucugcaucca uggagaaugc aaauauguga aggagcuccg ggcucccucc ugcaucugcc      480

acccggguua ccauggagag aggugucaug ggcugagccu cccaguggaa aaucgcuuau      540

auaccuauga ccacacaacc auccuggccg ugguggcugu ggugcuguca ucugucuguc      600

ugcuggucau cguggggcuu cucauguuua gguaccauag gagaggaggu uaugaugugg      660

aaaaugaaga gaaagugaag uugggcauga cuaauuccca cugaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  3855
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (wt)

<400>  3855
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca aacuccugcc agcccugcug cugcagcaug      120

uccuccugca ucuccuccug cuccccaucg ccauccccua ugcagaggga caaaggaaaa      180

gaagaaauac aauucaugaa uucaaaaaau cagcaaagac uacccuaauc aaaauagauc      240

cagcacugaa gauaaaaacc aaaaaaguga auacugcaga ccaaugugcu aauagaugua      300

cuaggaauaa aggacuucca uucacuugca aggcuuuugu uuuugauaaa gcaagaaaac      360

aaugccucug guuccccuuc aauagcaugu caaguggagu gaaaaaagaa uuuggccaug      420

aauuugaccu cuaugaaaac aaagacuaca uuagaaacug caucauuggu aaaggacgca      480

gcuacaaggg aacaguaucu aucacuaaga guggcaucaa augucagccc uggaguucca      540

ugauaccaca cgaacacagc uuuuugccuu cgagcuaucg ggguaaagac cuacaggaaa      600

acuacugucg aaauccucga ggggaagaag ggggacccug guguuucaca agcaauccag      660

agguacgcua cgaagucugu gacauuccuc aguguucaga aguugaaugc augaccugca      720

auggggagag uuaucgaggu cucauggauc auacagaauc aggcaagauu ugucagcgcu      780

gggaucauca gacaccacac cggcacaaau ucuugccuga aagauauccc gacaagggcu      840

uugaugauaa uuauugccgc aaucccgaug gccagccgag gccauggugc uauacucuug      900

acccucacac ccgcugggag uacugugcaa uuaaaacaug cgcugacaau acuaugaaug      960

acacugaugu uccuuuggaa acaacugaau gcauccaagg ucaaggagaa ggcuacaggg     1020

gcacugucaa uaccauuugg aauggaauuc caugucagcg uugggauucu caguauccuc     1080

acgagcauga caugacuccu gaaaauuuca agugcaagga ccuacgagaa aauuacugcc     1140

gaaauccaga ugggucugaa ucacccuggu guuuuaccac ugauccaaac auccgaguug     1200

gcuacugcuc ccaaauucca aacugugaua ugucacaugg acaagauugu uaucguggga     1260

auggcaaaaa uuauaugggc aacuuauccc aaacaagauc uggacuaaca uguucaaugu     1320

gggacaagaa cauggaagac uuacaucguc auaucuucug ggaaccagau gcaaguaagc     1380

ugaaugagaa uuacugccga aauccagaug augaugcuca uggacccugg ugcuacacgg     1440

gaaauccacu cauuccuugg gauuauugcc cuauuucucg uugugaaggu gauaccacac     1500

cuacaauagu caauuuagac caucccguaa uaucuugugc caaaacgaaa caauugcgag     1560

uuguaaaugg gauuccaaca cgaacaaaca uaggauggau gguuaguuug agauacagaa     1620

auaaacauau cugcggagga ucauugauaa aggagaguug gguucuuacu gcacgacagu     1680

guuucccuuc ucgagacuug aaagauuaug aagcuuggcu uggaauucau gauguccacg     1740

gaagaggaga ugagaaaugc aaacagguuc ucaauguuuc ccagcuggua uauggcccug     1800

aaggaucaga ucugguuuua augaagcuug ccaggccugc uguccuggau gauuuuguua     1860

guacgauuga uuuaccuaau uauggaugca caauuccuga aaagaccagu ugcaguguuu     1920

auggcugggg cuacacugga uugaucaacu augauggccu auuacgagug gcacaucucu     1980

auauaauggg aaaugagaaa ugcagccagc aucaucgagg gaaggugacu cugaaugagu     2040

cugaaauaug ugcuggggcu gaaaagauug gaucaggacc augugagggg gauuauggug     2100

gcccacuugu uugugagcaa cauaaaauga gaaugguucu uggugucauu guuccugguc     2160

guggaugugc cauuccaaau cguccuggua uuuuuguccg aguagcauau uaugcaaaau     2220

ggauacacaa aauuauuuua acauauaagg uaccacaguc auagggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  3856
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (wt)

<400>  3856
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaagccg cggcgaucgg caucgaccug ggcaccaccu      120

acuccugcgu ggggguguuc caacacggca agguggagau caucgccaac gaccagggca      180

accgcaccac ccccagcuac guggccuuca cggacaccga gcggcucauc ggggaugcgg      240

ccaagaacca gguggcgcug aacccgcaga acaccguguu ugacgcgaag cggcugauug      300

gccgcaaguu cggcgacccg guggugcagu cggacaugaa gcacuggccu uuccagguga      360

ucaacgacgg agacaagccc aaggugcagg ugagcuacaa gggggagacc aaggcauucu      420

accccgagga gaucucgucc auggugcuga ccaagaugaa ggagaucgcc gaggcguacc      480

ugggcuaccc ggugaccaac gcggugauca ccgugccggc cuacuucaac gacucgcagc      540

gccaggccac caaggaugcg ggugugaucg cggggcucaa cgugcugcgg aucaucaacg      600

agcccacggc cgccgccauc gccuacggcc uggacagaac gggcaagggg gagcgcaacg      660

ugcucaucuu ugaccugggc gggggcaccu ucgacguguc cauccugacg aucgacgacg      720

gcaucuucga ggugaaggcc acggccgggg acacccaccu ggguggggag gacuuugaca      780

acaggcuggu gaaccacuuc guggaggagu ucaagagaaa acacaagaag gacaucagcc      840

agaacaagcg agccgugagg cggcugcgca ccgccugcga gagggccaag aggacccugu      900

cguccagcac ccaggccagc cuggagaucg acucccuguu ugagggcauc gacuucuaca      960

cguccaucac cagggcgagg uucgaggagc ugugcuccga ccuguuccga agcacccugg     1020

agcccgugga gaaggcucug cgcgacgcca agcuggacaa ggcccagauu cacgaccugg     1080

uccuggucgg gggcuccacc cgcaucccca aggugcagaa gcugcugcag gacuucuuca     1140

acgggcgcga ccugaacaag agcaucaacc ccgacgaggc uguggccuac ggggcggcgg     1200

ugcaggcggc cauccugaug ggggacaagu ccgagaacgu gcaggaccug cugcugcugg     1260

acguggcucc ccugucgcug gggcuggaga cggccggagg cgugaugacu gcccugauca     1320

agcgcaacuc caccaucccc accaagcaga cgcagaucuu caccaccuac uccgacaacc     1380

aacccggggu gcugauccag guguacgagg gcgagagggc caugacgaaa gacaacaauc     1440

uguuggggcg cuucgagcug agcggcaucc cuccggcccc caggggcgug ccccagaucg     1500

aggugaccuu cgacaucgau gccaacggca uccugaacgu cacggccacg gacaagagca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg ccgccugagc aaggaggaga     1620

ucgagcgcau ggugcaggag gcggagaagu acaaagcgga ggacgaggug cagcgcgaga     1680

gggugucagc caagaacgcc cuggaguccu acgccuucaa caugaagagc gccguggagg     1740

augaggggcu caagggcaag aucagcgagg cggacaagaa gaaggugcug gacaaguguc     1800

aagaggucau cucguggcug gacgccaaca ccuuggccga gaaggacgag uuugagcaca     1860

agaggaagga gcuggagcag guguguaacc ccaucaucag cggacuguac cagggugccg     1920

guggucccgg gccugggggc uucggggcuc agggucccaa gggagggucu gggucaggcc     1980

ccaccauuga ggagguagau uagggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  3857
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (wt)

<400>  3857
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaagccg cggcgaucgg caucgaccug ggcaccaccu      120

acuccugcgu ggggguguuc caacacggca agguggagau caucgccaac gaccagggca      180

accgcaccac ccccagcuac guggccuuca cggacaccga gcggcucauc ggggaugcgg      240

ccaagaacca gguggcgcug aacccgcaga acaccguguu ugacgcgaag cggcugauug      300

gccgcaaguu cggcgacccg guggugcagu cggacaugaa gcacuggccu uuccagguga      360

ucaacgacgg agacaagccc aaggugcagg ugagcuacaa gggggagacc aaggcauucu      420

accccgagga gaucucgucc auggugcuga ccaagaugaa ggagaucgcc gaggcguacc      480

ugggcuaccc ggugaccaac gcggugauca ccgugccggc cuacuucaac gacucgcagc      540

gccaggccac caaggaugcg ggugugaucg cggggcucaa cgugcugcgg aucaucaacg      600

agcccacggc cgccgccauc gccuacggcc uggacagaac gggcaagggg gagcgcaacg      660

ugcucaucuu ugaccugggc gggggcaccu ucgacguguc cauccugacg aucgacgacg      720

gcaucuucga ggugaaggcc acggccgggg acacccaccu ggguggggag gacuuugaca      780

acaggcuggu gaaccacuuc guggaggagu ucaagagaaa acacaagaag gacaucagcc      840

agaacaagcg agccgugagg cggcugcgca ccgccugcga gagggccaag aggacccugu      900

cguccagcac ccaggccagc cuggagaucg acucccuguu ugagggcauc gacuucuaca      960

cguccaucac cagggcgagg uucgaggagc ugugcuccga ccuguuccga agcacccugg     1020

agcccgugga gaaggcucug cgcgacgcca agcuggacaa ggcccagauu cacgaccugg     1080

uccuggucgg gggcuccacc cgcaucccca aggugcagaa gcugcugcag gacuucuuca     1140

acgggcgcga ccugaacaag agcaucaacc ccgacgaggc uguggccuac ggggcggcgg     1200

ugcaggcggc cauccugaug ggggacaagu ccgagaacgu gcaggaccug cugcugcugg     1260

acguggcucc ccugucgcug gggcuggaga cggccggagg cgugaugacu gcccugauca     1320

agcgcaacuc caccaucccc accaagcaga cgcagaucuu caccaccuac uccgacaacc     1380

aacccggggu gcugauccag guguacgagg gcgagagggc caugacgaaa gacaacaauc     1440

uguuggggcg cuucgagcug agcggcaucc cuccggcccc caggggcgug ccccagaucg     1500

aggugaccuu cgacaucgau gccaacggca uccugaacgu cacggccacg gacaagagca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg ccgccugagc aaggaggaga     1620

ucgagcgcau ggugcaggag gcggagaagu acaaagcgga ggacgaggug cagcgcgaga     1680

gggugucagc caagaacgcc cuggaguccu acgccuucaa caugaagagc gccguggagg     1740

augaggggcu caagggcaag aucagcgagg cggacaagaa gaagguucug gacaaguguc     1800

aagaggucau cucguggcug gacgccaaca ccuuggccga gaaggacgag uuugagcaca     1860

agaggaagga gcuggagcag guguguaacc ccaucaucag cggacuguac cagggugccg     1920

guggucccgg gccuggcggc uucggggcuc agggucccaa gggagggucu gggucaggcc     1980

cuaccauuga ggagguggau uagggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  3858
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (wt)

<400>  3858
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuacugcca agggaaucgc cauaggcauc gaccugggca      120

ccaccuacuc cugugugggg guguuccagc acggcaaggu ggagaucauc gccaacgacc      180

agggcaaccg caccaccccc agcuacgugg ccuucacaga caccgagcgg cucauugggg      240

augcggccaa gaaccaggua gcaaugaauc cccagaacac uguuuuugau gcuaaacguc      300

ugaucggcag gaaauuuaau gauccuguug uacaagcaga uaugaaacuu uggccuuuuc      360

aagugauuaa ugaaggaggc aagcccaaag uccuuguguc cuacaaaggg gagaauaaag      420

cuuucuaccc ugaggaaauc ucuucgaugg uauugacuaa guugaaggag acugcugagg      480

ccuuuuuggg ccacccuguc accaaugcag ugauuaccgu gccagccuau uucaaugacu      540

cucaacguca ggcuacuaag gaugcaggug ugauugcugg acuuaaugug cuaagaauca      600

ucaaugagcc cacggcugcu gccauugccu augguuuaga uaaaggaggu caaggagaac      660

gacauguccu gauuuuugau cuggguggag gcacauuuga ugugucaauu cugaccauag      720

augaugggau uuuugaggua aaggccacug cuggggacac ucaccugggu ggggaggacu      780

uugacaacag gcuugugagc cacuucgugg aggaguucaa gaggaaacac aaaaaggaca      840

ucagccagaa caagcgagcc gugaggcggc ugcgcaccgc cugcgagagg gccaagagga      900

cccugucguc cagcacccag gccaaccuag aaauugauuc acuuuaugaa ggcauugacu      960

ucuauacauc caucaccaga gcucgauuug aagaguugug ugcagaccug uuuaggggua     1020

cccuggagcc uguagaaaaa gcgcuucggg augccaagau ggauaaggcu aaaauccaug     1080

acauuguuuu aguagggggc uccacccgca uccccaaggu gcagcggcug cuucaggacu     1140

acuucaaugg acgugaucuc aacaagagca ucaacccuga ugaggccgua gcauaugggg     1200

cugcgguaca agcagccauc cugauggggg acaagucuga gaagguacag gaccugcugc     1260

ugcuggacgu ggcuccccug ucccuggggc uggagacggc ugggggcgug augacugccc     1320

ugauaaagcg caacuccacc auccccacca agcagacaca gauuuucacc accuacucug     1380

acaaccaacc cggggugcug auccaggugu augagggcga gagggccaug acaaaggaca     1440

acaaccugcu ggggcgguuu gaccugacug gaaucccucc agcacccagg ggaguuccuc     1500

agaucgaggu gacguuugac auugaugcca augguauucu caaugucaca gccacggaca     1560

agagcaccgg caaggugaac aagaucacca ucaccaauga caagggccgc cugagcaagg     1620

aggagauuga gcgcaugguu cuggaugcug agaaauauaa agcugaagau gagguccaga     1680

gggagaaaau ugcugcaaag aaugccuuag aauccuaugc uuuuaacaug aagaguguug     1740

ugagugauga agguuugaag ggcaagauua gugagucuga uaaaaauaaa auauuggaua     1800

aaugcaacga gcuccuuucg uggcuggagg ucaaucaacu ggcagagaaa gaugaguuug     1860

aucauaagag aaaggaauug gagcagaugu guaacccuau caucacaaaa cucuaccaag     1920

gaggaugcac ugggccugcc ugcggaacag gguaugugcc uggaaggccu gccacaggcc     1980

ccacaauuga agaaguagau uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  3859
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (wt)

<400>  3859
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucugcccgug gcccggcuau cggcaucgac cugggcacca      120

ccuauucgug cgucgggguc uuccaacaug gcaaggugga gaucaucgcc aacgaccagg      180

gcaaucgcac cacccccagc uacguggccu ucacggacac cgagcgccuc aucggcgacg      240

ccgccaagaa ccagguggcc augaacccca ccaacaccau cuucgacgcc aagaggcuga      300

uuggacggaa auucgaggau gccacagugc agucggauau gaaacacugg ccguuccggg      360

uggugagcga gggaggcaag cccaaagugc aaguagagua caagggggag accaagaccu      420

ucuucccaga ggagauaucc uccauggucc ucacgaagau gaaggagauc gcggaagccu      480

accugggggg caaggugcac agcgcgguca uaacgguccc ggccuauuuc aacgacucgc      540

agcgccaggc caccaaggac gcaggcacca ucacggggcu caaugugcug cgcaucauca      600

acgagcccac ggcggcggcc aucgccuacg gccuggacaa gaagggcugc gcgggcggcg      660

agaagaacgu gcucaucuuu gaccugggcg guggcacuuu cgacgugucc auccugacca      720

ucgaggaugg caucuucgag gugaagucca cggccggcga cacccaccug ggcggugagg      780

acuucgacaa ccgcauggug agccaccugg cggaggaguu caagcgcaag cacaagaagg      840

acauugggcc caacaagcgc gccgugaggc ggcugcgcac cgcuugcgag cgcgccaagc      900

gcacccugag cucguccacg caggcgagca ucgagaucga cucgcucuac gagggcgugg      960

acuucuauac guccaucacg cgcgcccgcu ucgaggagcu caaugccgac cucuuucgcg     1020

ggacccugga gccgguggag aaggcgcugc gcgacgccaa gcuggacaag ggccagaucc     1080

aggagaucgu gcuggugggc ggcuccacuc guauccccaa gauccagaag cugcugcagg     1140

auuucuucaa cggcaaggag cugaacaaga gcaucaaccc cgacgaggcg guggccuaug     1200

gcgccgcggu gcaggcggcc auccucaucg gcgacaaauc agagaaugug caggaccugc     1260

ugcuacucga cgugaccccg uugucgcugg gcaucgagac agcuggcggu gucaugaccc     1320

cacucaucaa gaggaacacc acgaucccca ccaagcagac gcagaccuuc accaccuacu     1380

cggacaacca gagcagcgua cuggugcagg uauacgaggg cgaacgggcc augaccaagg     1440

acaauaaccu gcugggcaag uucgaccuga ccgggauucc cccugcgccu cgcggggucc     1500

cccaaaucga gguuaccuuc gacauugacg ccaauggcau ccuuaacguu accgccgccg     1560

acaagagcac cgguaaggaa aacaaaauca ccaucaccaa ugacaaaggu cgucugagca     1620

aggacgacau ugaccggaug gugcaggagg cggagcggua caaaucggaa gaugaggcga     1680

aucgcgaccg agucgcggcc aaaaacgccc uggaguccua uaccuacaac aucaagcaga     1740

cgguggaaga cgagaaacug aggggcaaga uuagcgagca ggacaaaaac aagauccucg     1800

acaaguguca ggaggugauc aacuggcucg accgaaacca gauggcagag aaagaugagu     1860

augaacacaa gcagaaagag cucgaaagag uuugcaaccc caucaucagc aaacuuuacc     1920

aagguggucc uggcggcggc agcggcggcg gcgguucagg agccuccggg ggacccacca     1980

ucgaagaagu ggacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  3860
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (wt)

<400>  3860
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucgguggugg gcauagaccu gggcuuccag agcugcuacg      120

ucgcuguggc ccgcgccggc ggcaucgaga cuaucgcuaa ugaguauagc gaccgcugca      180

cgccggcuug cauuucuuuu gguccuaaga aucguucaau uggagcagca gcuaaaagcc      240

agguaauuuc uaaugcaaag aacacagucc aaggauuuaa aagauuccau ggccgagcau      300

ucucugaucc auuuguggag gcagaaaaau cuaaccuugc auaugauauu gugcaguugc      360

cuacaggauu aacagguaua aaggugacau auauggagga agagcgaaau uuuaccacug      420

agcaagugac ugccaugcuu uuguccaaac ugaaggagac agccgaaagu guucuuaaga      480

agccuguagu ugacuguguu guuucgguuc cuuguuucua uacugaugca gaaagacgau      540

cagugaugga ugcaacacag auugcugguc uuaauugcuu gcgauuaaug aaugaaacca      600

cugcaguugc ucuugcauau ggaaucuaua agcaggaucu uccugccuua gaagagaaac      660

caagaaaugu aguuuuugua gacaugggcc acucugcuua ucaaguuucu guaugugcau      720

uuaauagagg aaaacugaaa guucuggcca cugcauuuga cacgacauug ggagguagaa      780

aauuugauga aguguuagua aaucacuucu gugaagaauu ugggaagaaa uacaagcuag      840

acauuaaguc caaaauccgu gcauuauuac gacucucuca ggagugugag aaacucaaga      900

aauugaugag ugcaaaugcu ucagaucucc cuuugagcau ugaauguuuu augaaugaug      960

uugauguauc uggaacuaug aauagaggca aauuucugga gaugugcaau gaucucuuag     1020

cuagagugga gccaccacuu cguaguguuu uggaacaaac caaguuaaag aaagaagaua     1080

uuuaugcagu ggagauaguu gguggugcua cacgaauccc ugcgguaaaa gagaagauca     1140

gcaaauuuuu cgguaaagaa cuuaguacaa cauuaaaugc ugaugaagcu gucacucgag     1200

gcugugcauu gcagugugcc aucuuaucgc cugcuuucaa agucagagaa uuuucuauca     1260

cugauguagu accauaucca auaucucuga gauggaauuc uccagcugaa gaagggucaa     1320

gugacuguga agucuuuucc aaaaaucaug cugcuccuuu cucuaaaguu cuuacauuuu     1380

auagaaagga accuuucacu cuugaggccu acuacagcuc uccucaggau uugcccuauc     1440

cagauccugc uauagcucag uuuucaguuc agaaagucac uccucagucu gauggcucca     1500

guucaaaagu gaaagucaaa guucgaguaa auguccaugg cauuuucagu guguccagug     1560

caucuuuagu ggagguucac aagucugagg aaaaugagga gccaauggaa acagaucaga     1620

augcaaagga ggaagagaag augcaagugg accaggagga accacauguu gaagagcaac     1680

agcagcagac accagcagaa aauaaggcag agucugaaga aauggagacc ucucaagcug     1740

gauccaagga uaaaaagaug gaccaaccac cccaagccaa gaaggcaaaa gugaagacca     1800

guacugugga ccugccaauc gagaaucagc uauuauggca gauagacaga gagaugcuca     1860

acuuguacau ugaaaaugag gguaagauga ucaugcagga uaaacuggag aaggagcgga     1920

augaugcuaa gaacgcagug gaggaauaug uguaugaaau gagagacaag cuuaguggug     1980

aauaugagaa guuugugagu gaagaugauc guaacaguuu uacuuugaaa cuggaagaua     2040

cugaaaauug guuguaugag gauggagaag accagccaaa gcaaguuuau guugauaagu     2100

uggcugaauu aaaaaaucua ggucaaccua uuaagauacg uuuccaggaa ucugaagaac     2160

gaccaaaauu auuugaagaa cuagggaaac agauccaaca guauaugaaa auaaucagcu     2220

cuuucaaaaa caaggaggac caguaugauc auuuggaugc ugcugacaug acaaagguag     2280

aaaaaagcac aaaugaagca auggagugga ugaauaacaa gcuaaaucug cagaacaagc     2340

agaguuugac cauggaucca guugucaagu caaaagagau ugaagcuaaa auuaaggagc     2400

ugacaaguac uuguagcccu auaauuucaa agcccaaacc caaaguggaa ccuccaaaag     2460

aggaacaaaa aaaugcagag cagaauggac caguggaugg acaaggagac aacccaggcc     2520

cccaggcugc ugagcagggu acagacacag cugugccuuc ggauucagac aagaagcuuc     2580

cugaaaugga cauugauuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  3861
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (wt)

<400>  3861
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucugugguug gcauugaccu cggcuuucuc aacugcuaca      120

uugcugucgc gagaaguggc ggcaucgaga ccaucgccaa ugaguacagc gacaggugua      180

ccccggccug uauaucauug ggaucaagaa cucgagccau uggaaaugca gcaaagagcc      240

agauagucac gaacguaaga aauacaauuc auggcuucaa aaagcuucau gggcgaucau      300

uugaugaucc cauugugcaa acugaaagga ucaggcuucc cuaugaacug cagaaaaugc      360

cuaauggaag ugcaggaguu aaggugcggu acuuagagga agagagaccu uuugcaauug      420

agcaaguuac uggaaugcug uuagccaagc uuaaagagac uucagaaaau gcuuugaaga      480

aaccaguggc ugacugugug auuucaauuc cuagcuuuuu uacugaugcc gagagaagau      540

cugugauggc ugcagcccag guugcaggcu uaaauuguuu aagguugaug aaugaaacua      600

cugcaguugc acuggcguau ggaauuuaua aacaggaucu ucccccauua gaugagaaac      660

caagaaaugu aguauuuauu gauaugggac auucugccua ucaggucuug guuugugcuu      720

uuaacaaagg aaaacuuaaa gucuuggcua cuaccuuuga uccauauuug gguggcagga      780

acuuugauga ggcuuuagua gacuacuucu gugaugaguu caagaccaaa uauaagauaa      840

augugaaaga aaacucucgg gccuuguugc guuuauauca ggaaugugaa aaacuaaaga      900

agcuaaugag ugcaaaugca ucagaucuuc cauugaacau ugaguguuuc augaaugacc      960

uugauguuuc uaguaaaaug aacagggcuc aauuugaaca acugugugcu ucccuuuugg     1020

ccaggguuga accaccuuua aaagcaguaa uggaacaagc uaacuuacaa cgugaagaca     1080

uuaguaguau agaaauugua ggaggagcaa cacgaauucc ugcagugaaa gaacaaauca     1140

cuaaauucuu ucuuaaagac auaaguacca cauuaaaugc ugaugaagcu guugcaagag     1200

gaugugcguu acagugugcg auucucucac cagcauuuaa agugcgugaa uuuuccauaa     1260

cagaccuugu ucccuauuca aucacauuaa gguggaagac cucuuuugaa gauggaagug     1320

gggaauguga aguuuucugu aagaaccauc cugccccauu cucaaaaguc auuacuuucc     1380

acaagaagga accauuugaa cuagaagcau uuuauacuaa uuuacaugaa gugccuuauc     1440

cugaugcaag aauugggagc uucacuauuc agaauguuuu uccacagucu gauggugaua     1500

guuccaaagu gaagguuaaa guucguguua acauccaugg aaucuucagu guggcuagcg     1560

caucaguaau ugagaagcaa aauuuggaag gcgaucacag ugaugcucca auggagacag     1620

aaacuucauu uaaaaaugaa aacaaagaua auauggauaa aaugcagguu gaucaagaag     1680

aagggcauca aaaaugucau gcugaacaca cuccagaaga ggaaauugau cauacaggag     1740

ccaaaacaaa gucagcuguc ucagacaaac aagaccgauu aaaucagaca cuuaaaaaag     1800

gaaaagucaa aaguauugau cuaccgaucc agaguagccu auguagacaa cuaggccaag     1860

aucuucucaa cagcuacauu gaaaaugagg ggaagaugau caugcaagau aaguuagaga     1920

aagaaagaaa ugaugcuaag aaugccguug aagaauaugu auaugauuuu agagacaggc     1980

ugggcacugu cuaugaaaaa uucaucacuc cagaagacuu gaguaaacug ucugcaguau     2040

uggaagacac agaaaauugg cuuuaugaag acggagagga ccaaccuaaa caaguuuaug     2100

uggauaagcu ucaagaacua aagaaauacg gccagccuau ucaaaugaag uacauggagc     2160

augaagagag accaaaagcc uuaaaugacu ugggaaaaaa gauccaacuu gucaugaaag     2220

ugauagaagc uuauagaaac aaggaugaaa gauaugauca ucuggauccu acugaaaugg     2280

aaaagguuga aaaauguauc agugaugcca ugaguuggcu gaauaguaag augaaugcac     2340

agaacaaacu aagucucacu caagauccug ugguaaaagu uucagaaaua guagcaaagu     2400

caaaggaacu ggauaauuuc uguaacccca ucauuuacaa gcccaaacca aaagcagaag     2460

uuccugaaga caaaccaaaa gcuaauagug aacacaaugg cccaauggau ggacagagug     2520

gaacugaaac uaaaucagau ucaacaaaag acagcucaca gcauacuaaa uccucuggag     2580

agauggaagu ggacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  3862
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (wt)

<400>  3862
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcucuccc ugguggccgc gaugcugcug cugcucagcg      120

cggcgcgggc cgaggaggag gacaagaagg aggacguggg cacggugguc ggcaucgacc      180

uggggaccac cuacuccugc gucggcgugu ucaagaacgg ccgcguggag aucaucgcca      240

acgaucaggg caaccgcauc acgccguccu augucgccuu cacuccugaa ggggaacguc      300

ugauuggcga ugccgccaag aaccagcuca ccuccaaccc cgagaacacg gucuuugacg      360

ccaagcggcu caucggccgc acguggaaug acccgucugu gcagcaggac aucaaguucu      420

ugccguucaa ggugguugaa aagaaaacua aaccauacau ucaaguugau auuggaggug      480

ggcaaacaaa gacauuugcu ccugaagaaa uuucugccau gguucucacu aaaaugaaag      540

aaaccgcuga ggcuuauuug ggaaagaagg uuacccaugc aguuguuacu guaccagccu      600

auuuuaauga ugcccaacgc caagcaacca aagacgcugg aacuauugcu ggccuaaaug      660

uuaugaggau caucaacgag ccuacggcag cugcuauugc uuauggccug gauaagaggg      720

agggggagaa gaacauccug guguuugacc uggguggcgg aaccuucgau gugucucuuc      780

ucaccauuga caaugguguc uucgaaguug uggccacuaa uggagauacu caucugggug      840

gagaagacuu ugaccagcgu gucauggaac acuucaucaa acuguacaaa aagaagacgg      900

gcaaagaugu caggaaagac aauagagcug ugcagaaacu ccggcgcgag guagaaaagg      960

ccaaacgggc ccugucuucu cagcaucaag caagaauuga aauugagucc uucuaugaag     1020

gagaagacuu uucugagacc cugacucggg ccaaauuuga agagcucaac auggaucugu     1080

uccggucuac uaugaagccc guccagaaag uguuggaaga uucugauuug aagaagucug     1140

auauugauga aauuguucuu guugguggcu cgacucgaau uccaaagauu cagcaacugg     1200

uuaaagaguu cuucaauggc aaggaaccau cccguggcau aaacccagau gaagcuguag     1260

cguauggugc ugcuguccag gcuggugugc ucucugguga ucaagauaca ggugaccugg     1320

uacugcuuga uguauguccc cuuacacuug guauugaaac ugugggaggu gucaugacca     1380

aacugauucc aaggaacaca guggugccua ccaagaaguc ucagaucuuu ucuacagcuu     1440

cugauaauca accaacuguu acaaucaagg ucuaugaagg ugaaagaccc cugacaaaag     1500

acaaucaucu ucuggguaca uuugaucuga cuggaauucc uccugcuccu cguggggucc     1560

cacagauuga agucaccuuu gagauagaug ugaaugguau ucuucgagug acagcugaag     1620

acaaggguac agggaacaaa aauaagauca caaucaccaa ugaccagaau cgccugacac     1680

cugaagaaau cgaaaggaug guuaaugaug cugagaaguu ugcugaggaa gacaaaaagc     1740

ucaaggagcg cauugauacu agaaaugagu uggaaagcua ugccuauucu cuaaagaauc     1800

agauuggaga uaaagaaaag cugggaggua aacuuuccuc ugaagauaag gagaccaugg     1860

aaaaagcugu agaagaaaag auugaauggc uggaaagcca ccaagaugcu gacauugaag     1920

acuucaaagc uaagaagaag gaacuggaag aaauuguuca accaauuauc agcaaacucu     1980

auggaagugc aggcccuccc ccaacuggug aagaggauac agcagaaaaa gaugaguugu     2040

agggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  3863
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (wt)

<400>  3863
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccac gggagcucgc ggugggcauc gaccugggca      120

ccaccuacuc gugcgugggc guguuucagc agggccgcgu ggagauccug gccaacgacc      180

agggcaaccg caccacgccc agcuacgugg ccuucaccga caccgagcgg cuggucgggg      240

acgcggccaa gagccaggcg gcccugaacc cccacaacac cguguucgau gccaagcggc      300

ugaucgggcg caaguucgcg gacaccacgg ugcagucgga caugaagcac uggcccuucc      360

ggguggugag cgagggcggc aagcccaagg ugcgcguaug cuaccgcggg gaggacaaga      420

cguucuaccc cgaggagauc ucguccaugg ugcugagcaa gaugaaggag acggccgagg      480

cguaccuggg ccagcccgug aagcacgcag ugaucaccgu gcccgccuau uucaaugacu      540

cgcagcgcca ggccaccaag gacgcggggg ccaucgcggg gcucaacgug uugcggauca      600

ucaaugagcc cacggcagcu gccaucgccu augggcugga ccggcggggc gcgggagagc      660

gcaacgugcu cauuuuugac cugggugggg gcaccuucga ugugucgguu cucuccauug      720

acgcuggugu cuuugaggug aaagccacug cuggagauac ccaccuggga ggagaggacu      780

ucgacaaccg gcucgugaac cacuucaugg aagaauuccg gcggaagcau gggaaggacc      840

ugagcgggaa caagcgugcc cugcgcaggc ugcgcacagc cugugagcgc gccaagcgca      900

cccuguccuc cagcacccag gccacccugg agauagacuc ccuguucgag ggcguggacu      960

ucuacacguc caucacucgu gcccgcuuug aggaacugug cucagaccuc uuccgcagca     1020

cccuggagcc gguggagaag gcccugcggg augccaagcu ggacaaggcc cagauucaug     1080

acgucguccu gguggggggc uccacacgca uccccaaggu gcagaaguug cugcaggacu     1140

ucuucaacgg caaggagcug aacaagagca ucaacccuga ugaggcugug gccuaugggg     1200

cugcugugca ggcggccgug uugauggggg acaaauguga gaaagugcag gaucuccugc     1260

ugcuggaugu ggcuccccug ucucuggggc uggagacagc agguggggug augaccacgc     1320

ugauccagag gaacgccacu auccccacca agcagaccca gacuuucacc accuacucgg     1380

acaaccagcc uggggucuuc auccaggugu augaggguga gagggccaug accaaggaca     1440

acaaccugcu ggggcguuuu gaacucagug gcaucccucc ugccccacgu ggaguccccc     1500

agauagaggu gacuuuugac auugaugcua auggcauccu gagcgugaca gccacugaca     1560

ggagcacagg uaaggcuaac aagaucacca ucaccaauga caagggccgg cugagcaagg     1620

aggaggugga gaggaugguu caugaagccg agcaguacaa ggcugaggau gaggcccaga     1680

gggacagagu ggcugccaaa aacucgcugg aggcccaugu cuuccaugug aaagguucuu     1740

ugcaagagga aagccuuagg gacaagauuc ccgaagagga caggcgcaaa augcaagaca     1800

agugucggga aguccuugcc uggcuggagc acaaccagcu ggcagagaag gaggaguaug     1860

agcaucagaa gagggagcug gagcaaaucu gucgccccau cuucuccagg cucuaugggg     1920

ggccuggugu cccugggggc agcaguugug gcacucaagc ccgccagggg gaccccagca     1980

ccggccccau cauugaggag guugauugag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  3864
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (wt)

<400>  3864
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccac gggagcucgc ggugggcauc gaccugggca      120

ccaccuacuc gugcgugggc guguuucagc agggccgcgu ggagauccug gccaacgacc      180

agggcaaccg caccacgccc agcuacgugg ccuucaccga caccgagcgg cuggucgggg      240

acgcggccaa gagccaggcg gcccugaacc cccacaacac cguguucgau gccaagcggc      300

ugaucgggcg caaguucgcg gacaccacgg ugcagucgga caugaagcac uggcccuucc      360

agguggugag cgagggcggc aagcccaagg ugcgcguaug cuaccgcggg gaggacaaga      420

cguucuaccc cgaggagauc ucguccaugg ugcugagcaa gaugaaggag acggccgagg      480

cguaccuggg ccagcccgug aagcacgcag ugaucaccgu gcccaccuau uucaguaacu      540

cgcagcgcca ggccaccaag gacgcggggg ccaucgcggg gcucaaggug cugccgauca      600

ucaaugaggc cacggcagca gccaucgccu augggcugga ccggcggggc gcgggaaagc      660

gcaacgugcu cauuuuugac cugggugggg gcaccuucga ugugucgguu cucuccauug      720

acgccggugu cuuugaggug aaagccacug cuggagauac ccaccuggga ggagaggacu      780

ucgacaaccg gcucgugaac cacuucaugg aagaauuccg gcggaagcau gggaaggacc      840

ugagcgggaa caagcgugcc cugcgcaggc ugcgcacagc cugugagcgc gccaagcgca      900

ccccguccuc cagcacccag gccacccugg agauagacuc ccuguucgag ggcguggacu      960

ucuacaaguc caucacucgu gcccgcuuug aggaacugug cucagaccuc uuccgcagca     1020

cccuggagcc gguggagaag gcccugcggg augccaagcu ggacaaggcc cagauucaug     1080

acuucguccu ggggggaggg cuccacucgc auccccaagg ugcagaaguu gcugcaggac     1140

uucuucaacg gcaaggagcu gaacaagagc aucaacccug aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  3865
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (wt)

<400>  3865
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccaagggac cugcaguugg uauugaucuu ggcaccaccu      120

acucuugugu ggguguuuuc cagcacggaa aagucgagau aauugccaau gaucagggaa      180

accgaaccac uccaagcuau gucgccuuua cggacacuga acgguugauc ggugaugccg      240

caaagaauca aguugcaaug aaccccacca acacaguuuu ugaugccaaa cgucugauug      300

gacgcagauu ugaugaugcu guuguccagu cugauaugaa acauuggccc uuuauggugg      360

ugaaugaugc uggcaggccc aagguccaag uagaauacaa gggagagacc aaaagcuucu      420

auccagagga ggugucuucu augguucuga caaagaugaa ggaaauugca gaagccuacc      480

uugggaagac uguuaccaau gcugugguca cagugccagc uuacuuuaau gacucucagc      540

gucaggcuac caaagaugcu ggaacuauug cuggucucaa uguacuuaga auuauuaaug      600

agccaacugc ugcugcuauu gcuuacggcu uagacaaaaa gguuggagca gaaagaaacg      660

ugcucaucuu ugaccuggga gguggcacuu uugauguguc aauccucacu auugaggaug      720

gaaucuuuga ggucaagucu acagcuggag acacccacuu ggguggagaa gauuuugaca      780

accgaauggu caaccauuuu auugcugagu uuaagcgcaa gcauaagaag gacaucagug      840

agaacaagag agcuguaaga cgccuccgua cugcuuguga acgugcuaag cguacccucu      900

cuuccagcac ccaggccagu auugagaucg auucucucua ugaaggaauc gacuucuaua      960

ccuccauuac ccgugcccga uuugaagaac ugaaugcuga ccuguuccgu ggcacccugg     1020

acccaguaga gaaagcccuu cgagaugcca aacuagacaa gucacagauu caugauauug     1080

uccugguugg ugguucuacu cguaucccca agauucagaa gcuucuccaa gacuucuuca     1140

auggaaaaga acugaauaag agcaucaacc cugaugaagc uguugcuuau ggugcagcug     1200

uccaggcagc caucuugucu ggagacaagu cugagaaugu ucaagauuug cugcucuugg     1260

augucacucc ucuuucccuu gguauugaaa cugcuggugg agucaugacu guccucauca     1320

agcguaauac caccauuccu accaagcaga cacagaccuu cacuaccuau ucugacaacc     1380

agccuggugu gcuuauucag guuuaugaag gcgagcgugc caugacaaag gauaacaacc     1440

ugcuuggcaa guuugaacuc acaggcauac cuccugcacc ccgagguguu ccucagauug     1500

aagucacuuu ugacauugau gccaauggua uacucaaugu cucugcugug gacaagagua     1560

cgggaaaaga gaacaagauu acuaucacua augacaaggg ccguuugagc aaggaagaca     1620

uugaacguau gguccaggaa gcugagaagu acaaagcuga agaugagaag cagagggaca     1680

aggugucauc caagaauuca cuugaguccu augccuucaa caugaaagca acuguugaag     1740

augagaaacu ucaaggcaag auuaacgaug aggacaaaca gaagauucug gacaagugua     1800

augaaauuau caacuggcuu gauaagaauc agacugcuga gaaggaagaa uuugaacauc     1860

aacagaaaga gcuggagaaa guuugcaacc ccaucaucac caagcuguac cagagugcag     1920

gaggcaugcc aggaggaaug ccugggggau uuccuggugg uggagcuccu cccucuggug     1980

gugcuuccuc agggcccacc auugaagagg uugauuaagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  3866
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (wt)

<400>  3866
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaagugcca gccgagcugc agcagcccgu cucgugggcg      120

ccgcagccuc ccggggcccu acggccgccc gccaccagga uagcuggaau ggccuuaguc      180

augaggcuuu uagacuuguu ucaaggcggg auuaugcauc agaagcaauc aagggagcag      240

uuguugguau ugauuugggu acuaccaacu ccugcguggc aguuauggaa gguaaacaag      300

caaaggugcu ggagaaugcc gaaggugcca gaaccacccc uucaguugug gccuuuacag      360

cagaugguga gcgacuuguu ggaaugccgg ccaagcgaca ggcugucacc aacccaaaca      420

auacauuuua ugcuaccaag cgucucauug gccggcgaua ugaugauccu gaaguacaga      480

aagacauuaa aaauguuccc uuuaaaauug uccgugccuc caauggugau gccuggguug      540

aggcucaugg gaaauuguau ucuccgaguc agauuggagc auuuguguug augaagauga      600

aagagacugc agaaaauuac uuggggcaca cagcaaaaaa ugcugugauc acagucccag      660

cuuauuucaa ugacucgcag agacaggcca cuaaagaugc uggccagaua ucuggacuga      720

augugcuucg ggugauuaau gagcccacag cugcugcucu ugccuauggu cuagacaaau      780

cagaagacaa agucauugcu guauaugauu uagguggugg aacuuuugau auuucuaucc      840

uggaaauuca gaaaggagua uuugagguga aauccacaaa uggggauacc uucuuaggug      900

gggaagacuu ugaccaggcc uugcuacggc acauugugaa ggaguucaag agagagacag      960

ggguugauuu gacuaaagac aacauggcac uucagagggu acgggaagcu gcugaaaagg     1020

cuaaauguga acucuccuca ucugugcaga cugacaucaa uuugcccuau cuuacaaugg     1080

auucuucugg acccaagcau uugaauauga aguugacccg ugcucaauuu gaagggauug     1140

ucacugaucu aaucagaagg acuaucgcuc caugccaaaa agcuaugcaa gaugcagaag     1200

ucagcaagag ugacauagga gaagugauuc uugugggugg caugacuagg augcccaagg     1260

uucagcagac uguacaggau cuuuuuggca gagccccaag uaaagcuguc aauccugaug     1320

aggcuguggc cauuggagcu gccauucagg gagguguguu ggccggcgau gucacggaug     1380

ugcugcuccu ugaugucacu ccccugucuc uggguauuga aacucuagga ggugucuuua     1440

ccaaacuuau uaauaggaau accacuauuc caaccaagaa gagccaggua uucucuacug     1500

ccgcugaugg ucaaacgcaa guggaaauua aaguguguca gggugaaaga gagauggcug     1560

gagacaacaa acuccuugga caguuuacuu ugauuggaau uccaccagcc ccucguggag     1620

uuccucagau ugaaguuaca uuugacauug augccaaugg gauaguacau guuucugcua     1680

aagauaaagg cacaggacgu gagcagcaga uuguaaucca gucuucuggu ggauuaagca     1740

aagaugauau ugaaaauaug guuaaaaaug cagagaaaua ugcugaagaa gaccggcgaa     1800

agaaggaacg aguugaagca guuaauaugg cugaaggaau cauucacgac acagaaacca     1860

agauggaaga auucaaggac caauuaccug cugaugagug caacaagcug aaagaagaga     1920

uuuccaaaau gagggagcuc cuggcuagaa aagacagcga aacaggagaa aauauuagac     1980

aggcagcauc cucucuucag caggcaucac ugaagcuguu cgaaauggca uacaaaaaga     2040

uggcaucuga gcgagaaggc ucuggaaguu cuggcacugg ggaacaaaag gaagaucaaa     2100

aggaggaaaa acaguaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  3867
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (wt)

<400>  3867
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcggacaagg aggccggcgg cagcgacggg ccccgagaaa      120

cggcucccac aucugcauau ucaucuccag cccggagucu uggggacaca ggaauaacgc      180

cucugucccc cucccauauu gugaacgaca cugacuccaa cgucucagaa cagcagucau      240

uucucguggu gguggccguc gacuuuggga ccacauccag uggcuaugcc uacagcuuca      300

ccaaggagcc ggaaugcauc caugugauga ggcgauggga gggaggugac ccuggugugu      360

ccaaucagaa gacuccaacc accaucuugc ugacucccga gaggaaguuc cacagcuucg      420

gguaugccgc cagggacuuu uaccaugacc uggaucccaa ugaggccaag caguggcugu      480

accuggagaa guucaagaug aagcugcaca ccacugggga ccucaccaug gauacagacc      540

ugacggcagc aaauggcaag aaagucaaag cccuugaaau cuuugcuuau gcccugcagu      600

acuuuaagga gcaggcgcug aaggagcuga gugaccaggc ggguucggag uucgagaacu      660

cugaugucag augggucauc acggugccug ccaucuggaa gcagccggcc aagcaguuca      720

ugagacaagc ugccuaccag gcaggccugg ccucccccga gaacucggag cagcucauca      780

uugccuugga gccugaggca gccucuaucu acugccgaaa gcugcggcua caccagauga      840

uugagcugag cagcaaggca gccgucaaug gguacagcgg cagugacaca guaggagcug      900

gguuuacaca ggcuaaggaa cacauacggc guaaucggca gagucggacc uuuuuggugg      960

agaaugucau aggagaaauc ugguccgagc uggaggaagg ugauaaguau gugguugugg     1020

acaguggcgg uggcaccgua gaccugacag uccaucagau ccgguuaccg gagggacacc     1080

uuaaggaacu guauaaagca acaggcggac ccuauggauc uuuaggagua gauuaugagu     1140

ucgaaaaacu ucuguauaaa auauuuggag aggauuuuau ugaacaauuc aaaaucaaac     1200

gcccugcagc cuggguugac uuaaugauug cguuugaguc ucgcaaaagg gcggcugccc     1260

cagacagaac uaacccgcug aacaucaccc ugcccuucuc cuucauugac uacuacaaga     1320

aguuccgcgg gcacagugug gagcacgccu ugcggaaaag caauguggau uuugugaagu     1380

gguccucgca ggggaugcug cggaugaguc cagaugccau gaacgcccuu uuuaagccga     1440

ccaucgauag caucauugag caucuccggg accuguuuca gaagcccgag guguccaccg     1500

ucaaguuccu cuuucuggug ggcggcuuug ccgaggcgcc ccugcugcag caggcggugc     1560

aggcugcuuu uggggaccag ugccggauca ucauccccca ggacgugggc cucaccaucc     1620

ucaagggugc cguccucuuu ggccuggacc ccgcggucau caaggugcgc cggucgccgc     1680

ucaccuacgg gguaggcgug cugaaccgcu acguggaggg caagcacccg ccugagaagc     1740

ugcuggugaa ggauggcacu cgguggugca ccgacgucuu ugacaaguuc aucucugccg     1800

accagucugu ggcucugggu gagcugguca agcguagcua caccccggcc aagcccuccc     1860

agcuggucau ugucaucaac aucuacagcu cugagcacga caacgucagc uucaucacug     1920

aucccggggu gaagaagugu ggcacgcucc gccuggaucu cacagggacc aguggcacug     1980

cggugcccgc ccggagggag auccagaccc uuaugcaguu cggggacacc gagaucaaag     2040

ccacagccau ugauauagcc acuucgaaga gugucaaagu ugggaucgac uucuuaaauu     2100

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  3868
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (wt)

<400>  3868
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuggcugucc cggagauggg ccugcagggg cuguacaucg      120

gcuccagccc ggagcggucc ccagugccua gcccacccgg cuccccgagg acccaggaaa      180

gcugcggcau ugccccccuc acacccucgc agucuccaaa acccgagguc cgagcccccc      240

agcaggccuc cuucucugug gugguggcca uugacuucgg caccacgucu aguggcuaug      300

cuuucagcuu ugccagugac ccugaggcca uccacaugau gaggaaaugg gagggcggag      360

acccgggcgu ggcccaccag aagaccccga ccugccugcu gcugacuccg gagggcgccu      420

uccacagcuu uggcuacacc gcccgcgauu acuaccauga ccuggacccc gaagaggcgc      480

gggacuggcu cuacuucgag aaguucaaga ugaagaucca cagcgccacg gaucucaccu      540

ugaagaccca gcuagaggca guaaauggaa agacgaugcc cgcccuggag guguucgccc      600

augcccugcg cuucuucagg gagcacgccc uucaggagcu gagggagcag agcccaucgc      660

ugccagagaa ggacacugug cgcugggugu ugacggugcc ugccaucugg aaacagccag      720

ccaagcaguu caugcgggag gcugccuacc uggcuggacu agugucccga gagaaugcag      780

agcagcuacu caucgcccug gagcccgagg ccgccucggu auacugccgc aagcugcgcc      840

ugcaccagcu ccuggaccug aguggccggg ccccaggugg ugggcgccug ggugagcgcc      900

gcuccaucga cuccagcuuc cgucaggcuc gggagcagcu gcgaaggucc cgccacagcc      960

gcacguuccu gguggaguca ggcguaggag agcugugggc agagaugcaa gcaggagacc     1020

gcuacguggu ggccgacugc ggcggaggca ccguggaccu gacggugcac cagcuggagc     1080

agccccaugg cacccucaag gagcucuaca aggcaucugg gggcccuuau ggcgcggugg     1140

gcguggaccu ggccuucgag cagcugcugu gccgcaucuu cggcgaggac uucaucgcca     1200

ccuucaaaag gcaacggccg gcagccuggg uagaucugac caucgccuuc gaggcucgca     1260

agcgcacugc uggcccacac cgugcagggg cgcucaacau cucgcugccc uucuccuuca     1320

uugacuucua ccgcaagcag cggggccaca acguggagac cgcucugcgc aggagcagcg     1380

ugaacuucgu gaaguggucc ucacagggga ugcuccgaau gucuugugaa gccaugaacg     1440

agcucuuuca gcccaccguc agcgggauca uccagcacau agaggcccug cuggcacggc     1500

cggaggugca gggugugaag cugcuguucc uagugggcgg cuucgccgag ucagcggugc     1560

ugcagcacgc ggugcaggcg gcgcugggcg cccgcggucu gcgugucgug gucccgcacg     1620

acgugggccu caccauccuc aaaggcgcgg ugcuguucgg ccaggcgccg ggcguggugc     1680

ggguccgccg cucgccgcuc accuauggcg ugggcgugcu caaccgcuuu gugccugggc     1740

gccacccgcc cgaaaagcug cugguucgcg acggccgccg cuggugcacc gacgucuucg     1800

agcgcuucgu ggccgccgag cagucggugg cccugggcga ggaggugcgg cgcagcuacu     1860

gcccggcgcg ucccggccag cggcgcguac ucaucaaccu guacugcugc gcggcagagg     1920

augcgcgcuu caucaccgac cccggcgugc gcaaaugcgg cgcgcucagc cucgagcuug     1980

agcccgccga cugcggccag gacaccgccg gcgcgccucc cggccgccgc gagauccgcg     2040

ccgccaugca guuuggcgac accgaaauua aggucaccgc cgucgacguc agcaccaauc     2100

gcuccgugcg cgcguccauc gacuuucuuu ccaacugagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  3869
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (wt)

<400>  3869
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagagaga ugacgaucuu aggaucggcu guuuugacuc      120

uccuguuggc cggcuauuug gcacaacagu auuuaccauu gccuacuccu aaagugauug      180

guauugaucu uggcaccacc uauuguucug uugggguguu uuuuccuggc acaggaaaag      240

uaaaggugau uccagaugaa aaugggcaua ucagcauacc cagcauggug ucuuuuacug      300

acaaugaugu auauguggga uaugaaagcg uagagcuggc agauucaaau ccucaaaaca      360

caauauauga ugccaaaaga uucauaggca agauuuuuac cgcagaagag uuggaggcug      420

aaauuggcag auacccauuu aagguuuuaa acaaaaaugg aaugguugag uuuucuguga      480

caaguaauga gaccaucaca guguccccag aauauguugg cucucgacua uuguugaagu      540

uaaaggaaau ggcagaggca uaucuuggaa ugccaguugc caaugcuguc auuucuguac      600

cagcagaauu ugaucuaaaa cagagaaauu caacaauuga agcugcuaac cuugcaggac      660

ugaagauuuu gaggguaaua aaugaaccca cagcagcagc uauggccuau ggucuccaca      720

aggcugacgu cuuccacguc uuggugauag acuugggcgg aggaacucua gaugugucuu      780

uacugaauaa acaaggaggg auguuucuaa cccgagcaau gucuggaaac aauaaacuug      840

gaggacagga cuucaaucag agauugcuuc aguacuuaua uaaacagauc uaucaaacau      900

auggcuucgu gcccucuagg aaagaggaaa uccacagauu gagacaagcu guggaaaugg      960

ucaaauuaaa ucugacucuu caucaaucug cucaguuguc aguauuacua acgguggagg     1020

agcaggacag gaaggaaccu cacaguagug acacugaacu gccaaaagac aaacuuuccu     1080

cagcagauga ccaucgcgug aacagugggu uuggacgugg ccuuucugau aagaaaagug     1140

gagaaaguca gguuuuauuu gaaacagaaa uaucacggaa acucuuugau acccuuaaug     1200

aagaccucuu ucagaaaaua cugguaccca uucagcaagu auugaaagaa ggccaccugg     1260

aaaagacuga gauugaugag gugguuuuag uugggggcuc cacucguauu ccucggaucc     1320

gucaagucau ucaagaguuc uuuggaaaag aucccaacac aucuguagac ccugaccuag     1380

caguaguaac gggaguggcu auccaagcag ggauugaugg aggcucuugg ccucuccaag     1440

ucagugcuuu agaaauuccc aauaagcauu uacaaaaaac caacuucaac ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  3870
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (wt)

<400>  3870
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcggccaucg gaguucaccu gggcugcacc ucagccugug      120

uggccgucua uaaggauggc cgggcuggug ugguugcaaa ugaugccggu gaccgaguua      180

cuccagcugu uguugcuuac ucagaaaaug aagagauugu uggauuggca gcaaaacaaa      240

guagaauaag aaauauuuca aauacaguaa ugaaaguaaa gcagauccug ggcagaagcu      300

ccagugaucc acaagcucag aaauacaucg cggaaaguaa auguuuaguc auugaaaaaa      360

augggaaauu acgauaugaa auagauacug gagaagaaac aaaauuuguu aacccagaag      420

auguugccag acugauauuu aguaaaauga aagaaacggc acauucugua uugggcucag      480

augcaaauga uguaguuauu acugucccgu uugauuuugg agaaaagcaa aaaaaugcuc      540

uuggagaagc agcuagagcu gcuggauuua auguuuugcg auuaauucac gaaccgucug      600

cagcucuucu ugcuuaugga auuggacaag acuccccuac uggaaaaagc aauauuuugg      660

uguuuaagcu uggaggaaca uccuuaucuc ucagcgucau ggaaguuaac aguggaauau      720

aucggguucu uucaacaaac acugaugaua acaucggugg ugcacauuuc acagaaaccu      780

uagcacagua ucuagcuucu gaguuccaaa gauccuucaa acaugaugug agaggaaaug      840

cgcgagccau gaugaaauua acgaacagug cugaaguagc gaaacauucu uugucaaccu      900

ugggaagugc caacuguuuu cuugacucau uauaugaagg ucaagauuuu gauugcaaug      960

uguccagagc aagauuugaa cuucuuuguu cuccacuuuu uaauaagugu auagaagcaa     1020

ucagaggacu cuuagaucaa aauggauuua cagcagauga uaucaacaag guuguccuuu     1080

guggaggguc uucucgaauc ccaaagcuac agcaacugau uaaagaucuu uucccagcug     1140

uugagcuucu caauucuauc ccuccugaug aagugauccc uauuggugca gcuauagaag     1200

caggaauucu uauugggaaa gaaaaccugu ugguggaaga cucucuuaug auagaguguu     1260

cagccagaga uauuuuaguu aagggugugg acgaaucagg agccaguaga uucacagugc     1320

uguuuccauc agggacuccu uugccagcuc gaagacaaca cacauugcaa gccccuggaa     1380

gcauaucuuc agugugccuu gaacucuaug agucugaugg gaagaacucu gccaaagagg     1440

aaaccaaguu ugcacagguu guacuccagg auuuagauaa aaaagaaaau ggauuacgug     1500

auauauuagc uguucuuacu augaaaaggg auggaucuuu acaugugaca ugcacagauc     1560

aagaaacugg aaaaugugaa gcaaucucua uugagauagc aucuuaggga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  3871
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (wt)

<400>  3871
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucgguggugg gguuggacgu gggcucgcag agcugcuaca      120

ucgcgguagc ccgggccggg ggcaucgaga ccaucgccaa ugaguucagc gaccggugca      180

ccccgucagu cauaucauuu ggaucaaaaa auagaacaau cggaguugca gccaaaaauc      240

agcaaaucac ucaugcaaac aauacggugu cuaacuucaa aagauuucau ggccgagcau      300

ucaaugaccc cuucauucaa aaggagaagg aaaacuugag uuacgauuug guuccauuga      360

aaaauggugg aguuggaaua aagguaaugu acauggguga agaacaucua uuuagugugg      420

agcagauaac agccauguug uugacuaagc ugaaggaaac ugcugaaaac agccucaaga      480

aaccaguaac agauuguguu auuucagucc ccuccuucuu uacagaugcu gagaggcgau      540

cuguguuaga ugcugcacag auuguuggcc uaaacuguuu aagacuuaug aaugacauga      600

cagcuguugc uuugaauuac ggaauuuaua agcaggaucu cccaagccug gaugagaaac      660

cucggauagu gguuuuuguu gauaugggac auucagcuuu ucaagugucu gcuugugcuu      720

uuaacaaggg aaaauugaag guacugggaa cagcuuuuga uccuuucuua ggaggaaaaa      780

acuucgauga aaaguuagug gaacauuuuu gugcagaauu uaaaacuaag uacaaguugg      840

augcaaaauc caaaauacga gcacuccuac gucuguauca ggaaugugaa aaacugaaaa      900

agcuaaugag cucuaacagc acagaccuuc cacugaauau cgaaugcuuu augaaugaua      960

aagauguuuc cggaaagaug aacaggucac aauuugaaga acucugugcu gaacuucugc     1020

aaaagauaga aguaccccuu uauucacugu uggaacaaac ucaucucaaa guagaagaug     1080

ugagugcagu ugagauuguu ggaggcgcua cacgaauucc agcugugaag gaaagaauug     1140

ccaaauucuu uggaaaagau auuagcacaa cacucaaugc agaugaagca guagccagag     1200

gaugugcauu acagugugca auacuuuccc cggcauuuaa aguuagagaa uuuuccguca     1260

cagaugcagu uccuuuucca auaucucuga ucuggaacca ugauucagaa gauacugaag     1320

guguucauga agucuuuagu cgaaaccaug cugcuccuuu cuccaaaguu cucaccuuuc     1380

ugagaagggg gccuuuugag cuagaagcuu ucuauucuga uccccaagga guuccauauc     1440

cagaagcaaa aauaggccgc uuuguaguuc agaauguuuc ugcacagaaa gauggagaaa     1500

aaucuagagu aaaagucaaa gugcgaguca acacccaugg cauuuucacc aucucuacgg     1560

caucuauggu ggagaaaguc ccaacugagg agaaugaaau gucuucugaa gcugacaugg     1620

agugucugaa ucagagacca ccagaaaacc cagacacuga uaaaaauguc cagcaagaca     1680

acagugaagc uggaacacag ccccagguac aaacugaugc ucaacaaacc ucacagucuc     1740

ccccuucacc ugaacuuacc ucagaagaaa acaaaauccc agaugcugac aaagcaaaug     1800

aaaaaaaagu ugaccagccu ccagaagcua aaaagcccaa aauaaaggug gugaauguug     1860

agcugccuau ugaagccaac uuggucuggc aguuagggaa agaccuucuu aacauguaua     1920

uugagacaga ggguaagaug auaaugcaag auaaauugga aaaagaaagg aaugaugcua     1980

aaaaugcagu ugaggaauau guguaugagu ucagagacaa gcugugugga ccauaugaaa     2040

aauuuauaug ugagcaggau caucaaaauu uuuugagacu ccucacagaa acugaagacu     2100

ggcuguauga agaaggagag gaccaagcua aacaagcaua uguugacaag uuggaagaau     2160

uaaugaaaau uggcacucca guuaaaguuc gguuucagga agcugaagaa cggccaaaaa     2220

uguuugaaga acuaggacag aggcugcagc auuaugccaa gauagcagcu gacuucagaa     2280

auaaggauga gaaauacaac cauauugaug agucugaaau gaaaaaagug gagaagucug     2340

uuaaugaagu gauggaaugg augaauaaug ucaugaaugc ucaggcuaaa aagagucuug     2400

aucaggaucc aguuguacgu gcucaggaaa uuaaaacaaa aaucaaggaa uugaacaaca     2460

caugugaacc cguuguaaca caaccgaaac caaaaauuga aucacccaaa cuggaaagaa     2520

cuccaaaugg cccaaauauu gauaaaaagg aagaagauuu agaagacaaa aacaauuuug     2580

gugcugaacc uccacaucag aauggugaau guuacccuaa ugagaaaaau ucuguuaaua     2640

uggacuugga cuagggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  3872
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (wt)

<400>  3872
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagacaaag uuaggaggca gaggccgagg aggcgagucu      120

guugggccuu gguggcugug cucuuggcag accuguuggc acugagugau acacuggcag      180

ugaugucugu ggaccugggc agugagucca ugaagguggc cauugucaaa ccuggagugc      240

ccauggaaau ugucuugaau aaggaaucuc ggaggaaaac accggugauc gugacccuga      300

aagaaaauga aagauucuuu ggagacagug cagcaagcau ggcgauuaag aauccaaagg      360

cuacgcuacg uuacuuccag caccuccugg ggaagcaggc agauaacccc cauguagcuc      420

uuuaccaggc ccgcuucccg gagcacgagc ugacuuucga cccacagagg cagacugugc      480

acuuucagau cagcucgcag cugcaguucu caccugagga aguguugggc augguucuca      540

auuauucucg uucucuagcu gaagauuuug cagagcagcc caucaaggau gcagugauca      600

ccgugccagu cuucuucaac caggccgagc gccgagcugu gcugcaggcu gcucguaugg      660

cuggccucaa agugcugcag cucaucaaug acaacaccgc cacugcccuc agcuauggug      720

ucuuccgccg gaaagauauu aacaccacug cccagaauau cauguucuau gacaugggcu      780

caggcagcac cguaugcacc auugugaccu accagauggu gaagacuaag gaagcuggga      840

ugcagccaca gcugcagauc cggggaguag gauuugaccg uacccugggg ggccuggaga      900

uggagcuccg gcuucgagaa cgccuggcug ggcuuuucaa ugagcagcgc aagggucaga      960

gagcaaagga ugugcgggag aacccgcgug ccauggccaa gcugcugcgu gaggcuaauc     1020

ggcucaaaac cguccucagu gccaacgcug accacauggc acagauugaa ggccugaugg     1080

augaugugga cuucaaggca aaagugacuc guguggaauu ugaggaguug ugugcagacu     1140

uguuugagcg ggugccuggg ccuguacagc aggcccucca gagugccgaa augagucugg     1200

augagauuga gcaggugauc cuggugggug gggccacucg gguccccaga guucaggagg     1260

ugcugcugaa ggccgugggc aaggaggagc uggggaagaa caucaaugca gaugaagcag     1320

ccgccauggg ggcaguguac caggcagcug cgcucagcaa agccuuuaaa gugaagccau     1380

uugucguccg agaugcagug gucuacccca uccuggugga guucacgagg gagguggagg     1440

aggagccugg gauucacagc cugaagcaca auaaacgggu acucuucucu cggauggggc     1500

ccuacccuca acgcaaaguc aucaccuuua accgcuacag ccaugauuuc aacuuccaca     1560

ucaacuacgg cgaccugggc uuccuggggc cugaagaucu ucggguauuu ggcucccaga     1620

aucugaccac agugaagcua aaaggggugg gugacagcuu caagaaguau ccugacuacg     1680

aguccaaggg caucaaggcu cacuucaacc uggaugagag uggcgugcuc agucuagaca     1740

ggguggaguc uguauuugag acacugguag aggacagcgc agaagaggaa ucuacucuca     1800

ccaaacuugg caacaccauu uccagccugu uuggaggcgg uaccacacca gaugccaagg     1860

agaaugguac ugauacuguc caggaggaag aggagagccc ugcagagggg agcaaggacg     1920

agccugggga gcagguggag cucaaggagg aagcugaggc cccaguggag gauggcucuc     1980

agcccccacc cccugaaccu aagggagaug caaccccuga gggagaaaag gccacagaaa     2040

aagaaaaugg ggacaagucu gaggcccaga aaccaaguga gaaggcagag gcagggccug     2100

agggcgucgc uccagcccca gagggagaga agaagcagaa gcccgccagg aagcggcgaa     2160

ugguagagga gaucggggug gagcugguug uucuggaccu gccugacuug ccagaggaua     2220

agcuggcuca gucggugcag aaacuucagg acuugacacu ccgagaccug gagaagcagg     2280

aacgggaaaa agcugccaac agcuuggaag cauucauauu ugagacccag gacaagcugu     2340

accagcccga guaccaggaa guguccacag aggagcagcg ugaggagauc ucugggaagc     2400

ucagcgccgc auccaccugg cuggaggaug aggguguugg agccaccaca gugauguuga     2460

aggagaagcu ggcugagcug aggaagcugu gccaagggcu guuuuuucgg guagaggagc     2520

gcaagaagug gcccgaacgg cugucugccc ucgauaaucu ccucaaccau uccagcaugu     2580

uccucaaggg ggcccggcuc aucccagaga uggaccagau cuucacugag guggagauga     2640

caacguuaga gaaagucauc aaugagaccu gggccuggaa gaaugcaacu cuggccgagc     2700

aggcuaagcu gcccgccaca gagaagccug uguugcucuc aaaagacauu gaagcuaaga     2760

ugauggcccu ggaccgagag gugcaguauc ugcucaauaa ggccaaguuu accaagcccc     2820

ggccccggcc uaaggacaag aaugggaccc gggcagagcc accccucaau gccagugcca     2880

gugaccaggg ggagaagguc aucccuccag caggccagac ugaagaugca gagcccauuu     2940

cagaaccuga gaaaguagag acuggauccg agccaggaga cacugagccu uuggaguuag     3000

gagguccugg agcagaaccu gaacagaaag aacaaucgac aggacagaag cggccuuuga     3060

agaacgacga acuauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  3873
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (wt)

<400>  3873
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccugaggaaa cccagaccca agaccaaccg auggaggagg      120

aggagguuga gacguucgcc uuucaggcag aaauugccca guugauguca uugaucauca      180

auacuuucua cucgaacaaa gagaucuuuc ugagagagcu cauuucaaau ucaucagaug      240

cauuggacaa aauccgguau gaaagcuuga cagaucccag uaaauuagac ucugggaaag      300

agcugcauau uaaccuuaua ccgaacaaac aagaucgaac ucucacuauu guggauacug      360

gaauuggaau gaccaaggcu gacuugauca auaaccuugg uacuaucgcc aagucuggga      420

ccaaagcguu cauggaagcu uugcaggcug gugcagauau cucuaugauu ggccaguucg      480

guguugguuu uuauucugcu uauuugguug cugagaaagu aacugugauc accaaacaua      540

acgaugauga gcaguacgcu ugggaguccu cagcaggggg aucauucaca gugaggacag      600

acacagguga accuaugggu cguggaacaa aaguuauccu acaccugaaa gaagaccaaa      660

cugaguacuu ggaggaacga agaauaaagg agauugugaa gaaacauucu caguuuauug      720

gauaucccau uacucuuuuu guggagaagg aacgugauaa agaaguaagc gaugaugagg      780

cugaagaaaa ggaagacaaa gaagaagaaa aagaaaaaga agagaaagag ucggaagaca      840

aaccugaaau ugaagauguu gguucugaug aggaagaaga aaagaaggau ggugacaaga      900

agaagaagaa gaagauuaag gaaaaguaca ucgaucaaga agagcucaac aaaacaaagc      960

ccaucuggac cagaaauccc gacgauauua cuaaugagga guacggagaa uucuauaaga     1020

gcuugaccaa ugacugggaa gaucacuugg cagugaagca uuuuucaguu gaaggacagu     1080

uggaauucag agcccuucua uuugucccac gacgugcucc uuuugaucug uuugaaaaca     1140

gaaagaaaaa gaacaacauc aaauuguaug uacgcagagu uuucaucaug gauaacugug     1200

aggagcuaau cccugaauau cugaacuuca uuagaggggu gguagacucg gaggaucucc     1260

cucuaaacau aucccgugag auguugcaac aaagcaaaau uuugaaaguu aucaggaaga     1320

auuuggucaa aaaaugcuua gaacucuuua cugaacuggc ggaagauaaa gagaacuaca     1380

agaaauucua ugagcaguuc ucuaaaaaca uaaagcuugg aauacacgaa gacucucaaa     1440

aucggaagaa gcuuucagag cuguuaaggu acuacacauc ugccucuggu gaugagaugg     1500

uuucucucaa ggacuacugc accagaauga aggagaacca gaaacauauc uauuauauca     1560

caggugagac caaggaccag guagcuaacu cagccuuugu ggaacgucuu cggaaacaug     1620

gcuuagaagu gaucuauaug auugagccca uugaugagua cuguguccaa cagcugaagg     1680

aauuugaggg gaagacuuua gugucaguca ccaaagaagg ccuggaacuu ccagaggaug     1740

aagaagagaa aaagaagcag gaagagaaaa aaacaaaguu ugagaaccuc ugcaaaauca     1800

ugaaagacau auuggagaaa aaaguugaaa aggugguugu gucaaaccga uuggugacau     1860

cuccaugcug uauugucaca agcacauaug gcuggacagc aaacauggag agaaucauga     1920

aagcucaagc ccuaagagac aacucaacaa uggguuacau ggcagcaaag aaacaccugg     1980

agauaaaccc ugaccauucc auuauugaga ccuuaaggca aaaggcagag gcugauaaga     2040

acgacaaguc ugugaaggau cuggucaucu ugcuuuauga aacugcgcuc cugucuucug     2100

gcuucagucu ggaagauccc cagacacaug cuaacaggau cuacaggaug aucaaacuug     2160

gucuggguau ugaugaagau gacccuacug cugaugauac cagugcugcu guaacugaag     2220

aaaugccacc ccuugaagga gaugacgaca caucacgcau ggaagaagua gacuaaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  3874
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (wt)

<400>  3874
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gauuccagua aauuagacuc ugggaaaggg cugcauauua      120

accuuguacc aaacaaacaa aaucaaaccc ucacuauugu ggacacuaga auuggaauga      180

ccaagacuga cuugaucaau aaccucggua cugucaccaa gucugggacc aaagcauuca      240

uggaagcuuu gcaggcugau gcagauaucu cuaugauugg ccauuucggg guugguuuuu      300

auucugcuua uuugguugcc aagaaaguaa cugugaucag caaacauaac aaugaugagc      360

aguacaccug ggaguccuca gcagggggau cauucacagu gaggacagac gagugaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  3875
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (wt)

<400>  3875
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccugaggaag ugcaccaugg agaggaggag guggagacuu      120

uugccuuuca ggcagaaauu gcccaacuca ugucccucau caucaauacc uucuauucca      180

acaaggagau uuuccuucgg gaguugaucu cuaaugcuuc ugaugccuug gacaagauuc      240

gcuaugagag ccugacagac ccuucgaagu uggacagugg uaaagagcug aaaauugaca      300

ucauccccaa cccucaggaa cguacccuga cuuugguaga cacaggcauu ggcaugacca      360

aagcugaucu cauaaauaau uugggaacca uugccaaguc ugguacuaaa gcauucaugg      420

aggcucuuca ggcuggugca gacaucucca ugauugggca guuugguguu ggcuuuuauu      480

cugccuacuu gguggcagag aaagugguug ugaucacaaa gcacaacgau gaugaacagu      540

augcuuggga gucuucugcu ggagguuccu ucacugugcg ugcugaccau ggugagccca      600

uuggcagggg uaccaaagug auccuccauc uuaaagaaga ucagacagag uaccuagaag      660

agaggcgggu caaagaagua gugaagaagc auucucaguu cauaggcuau cccaucaccc      720

uuuauuugga gaaggaacga gagaaggaaa uuagugauga ugaggcagag gaagagaaag      780

gugagaaaga agaggaagau aaagaugaug aagaaaaacc caagaucgaa gauguggguu      840

cagaugagga ggaugacagc gguaaggaua agaagaagaa aacuaagaag aucaaagaga      900

aauacauuga ucaggaagaa cuaaacaaga ccaagccuau uuggaccaga aacccugaug      960

acaucaccca agaggaguau ggagaauucu acaagagccu cacuaaugac ugggaagacc     1020

acuuggcagu caagcacuuu ucuguagaag gucaguugga auucagggca uugcuauuua     1080

uuccucgucg ggcucccuuu gaccuuuuug agaacaagaa gaaaaagaac aacaucaaac     1140

ucuauguccg ccguguguuc aucauggaca gcugugauga guugauacca gaguaucuca     1200

auuuuauccg uggugugguu gacucugagg aucugccccu gaacaucucc cgagaaaugc     1260

uccagcagag caaaaucuug aaagucauuc gcaaaaacau uguuaagaag ugccuugagc     1320

ucuucucuga gcuggcagaa gacaaggaga auuacaagaa auucuaugag gcauucucua     1380

aaaaucucaa gcuuggaauc cacgaagacu ccacuaaccg ccgccgccug ucugagcugc     1440

ugcgcuauca uaccucccag ucuggagaug agaugacauc ucugucagag uauguuucuc     1500

gcaugaagga gacacagaag uccaucuauu acaucacugg ugagagcaaa gagcaggugg     1560

ccaacucagc uuuuguggag cgagugcgga aacggggcuu cgagguggua uauaugaccg     1620

agcccauuga cgaguacugu gugcagcagc ucaaggaauu ugaugggaag agccuggucu     1680

caguuaccaa ggagggucug gagcugccug aggaugagga ggagaagaag aagauggaag     1740

agagcaaggc aaaguuugag aaccucugca agcucaugaa agaaaucuua gauaagaagg     1800

uugagaaggu gacaaucucc aauagacuug ugucuucacc uugcugcauu gugaccagca     1860

ccuacggcug gacagccaau auggagcgga ucaugaaagc ccaggcacuu cgggacaacu     1920

ccaccauggg cuauaugaug gccaaaaagc accuggagau caacccugac caccccauug     1980

uggagacgcu gcggcagaag gcugaggccg acaagaauga uaaggcaguu aaggaccugg     2040

uggugcugcu guuugaaacc gcccugcuau cuucuggcuu uucccuugag gauccccaga     2100

cccacuccaa ccgcaucuau cgcaugauca agcuaggucu agguauugau gaagaugaag     2160

uggcagcaga ggaacccaau gcugcaguuc cugaugagau ccccccucuc gagggcgaug     2220

aggaugcguc ucgcauggaa gaagucgauu agggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  3876
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (wt)

<400>  3876
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agggcccugu gggugcuggg ccucugcugc guccugcuga      120

ccuucggguc ggucagagcu gacgaugaag uugaugugga ugguacagua gaagaggauc      180

uggguaaaag uagagaagga ucaaggacgg augaugaagu aguacagaga gaggaagaag      240

cuauucaguu ggauggauua aaugcaucac aaauaagaga acuuagagag aagucggaaa      300

aguuugccuu ccaagccgaa guuaacagaa ugaugaaacu uaucaucaau ucauuguaua      360

aaaauaaaga gauuuuccug agagaacuga uuucaaaugc uucugaugcu uuagauaaga      420

uaaggcuaau aucacugacu gaugaaaaug cucuuucugg aaaugaggaa cuaacaguca      480

aaauuaagug ugauaaggag aagaaccugc ugcaugucac agacaccggu guaggaauga      540

ccagagaaga guugguuaaa aaccuuggua ccauagccaa aucugggaca agcgaguuuu      600

uaaacaaaau gacugaagca caggaagaug gccagucaac uucugaauug auuggccagu      660

uuggugucgg uuucuauucc gccuuccuug uagcagauaa gguuauuguc acuucaaaac      720

acaacaacga uacccagcac aucugggagu cugacuccaa ugaauuuucu guaauugcug      780

acccaagagg aaacacucua ggacggggaa cgacaauuac ccuugucuua aaagaagaag      840

caucugauua ccuugaauug gauacaauua aaaaucucgu caaaaaauau ucacaguuca      900

uaaacuuucc uauuuaugua uggagcagca agacugaaac uguugaggag cccauggagg      960

aagaagaagc agccaaagaa gagaaagaag aaucugauga ugaagcugca guagaggaag     1020

aagaagaaga aaagaaacca aagacuaaaa aaguugaaaa aacugucugg gacugggaac     1080

uuaugaauga uaucaaacca auauggcaga gaccaucaaa agaaguagaa gaagaugaau     1140

acaaagcuuu cuacaaauca uuuucaaagg aaagugauga ccccauggcu uauauucacu     1200

uuacugcuga aggggaaguu accuucaaau caauuuuauu uguacccaca ucugcuccac     1260

guggucuguu ugacgaauau ggaucuaaaa agagcgauua cauuaagcuc uaugugcgcc     1320

guguauucau cacagacgac uuccaugaua ugaugccuaa auaccucaau uuugucaagg     1380

guguggugga cucagaugau cuccccuuga auguuucccg cgagacucuu cagcaacaua     1440

aacugcuuaa ggugauuagg aagaagcuug uucguaaaac gcuggacaug aucaagaaga     1500

uugcugauga uaaauacaau gauacuuuuu ggaaagaauu ugguaccaac aucaagcuug     1560

gugugauuga agaccacucg aaucgaacac gucuugcuaa acuucuuagg uuccagucuu     1620

cucaucaucc aacugacauu acuagccuag accaguaugu ggaaagaaug aaggaaaaac     1680

aagacaaaau cuacuucaug gcugggucca gcagaaaaga ggcugaaucu ucuccauuug     1740

uugagcgacu ucugaaaaag ggcuaugaag uuauuuaccu cacagaaccu guggaugaau     1800

acuguauuca ggcccuuccc gaauuugaug ggaagagguu ccagaauguu gccaaggaag     1860

gagugaaguu cgaugaaagu gagaaaacua aggagagucg ugaagcaguu gagaaagaau     1920

uugagccucu gcugaauugg augaaagaua aagcccuuaa ggacaagauu gaaaaggcug     1980

uggugucuca gcgccugaca gaaucuccgu gugcuuuggu ggccagccag uacggauggu     2040

cuggcaacau ggagagaauc augaaagcac aagcguacca aacgggcaag gacaucucua     2100

caaauuacua ugcgagucag aagaaaacau uugaaauuaa ucccagacac ccgcugauca     2160

gagacaugcu ucgacgaauu aaggaagaug aagaugauaa aacaguuuug gaucuugcug     2220

ugguuuuguu ugaaacagca acgcuucggu caggguaucu uuuaccagac acuaaagcau     2280

auggagauag aauagaaaga augcuucgcc ucaguuugaa cauugacccu gaugcaaagg     2340

uggaagaaga gcccgaagaa gaaccugaag agacagcaga agacacaaca gaagacacag     2400

agcaagacga agaugaagaa auggaugugg gaacagauga agaagaagaa acagcaaagg     2460

aaucuacagc ugaaaaagau gaauuguaag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  3877
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (wt)

<400>  3877
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgcgcgagc ugcgggcgcu gcugcugugg ggccgccgcc      120

ugcggccuuu gcugcgggcg ccggcgcugg cggccgugcc gggaggaaaa ccaauucugu      180

guccucggag gaccacagcc caguugggcc ccaggcgaaa cccagccugg agcuugcagg      240

caggacgacu guucagcacg cagaccgccg aggacaagga ggaaccccug cacucgauua      300

ucagcagcac agagagcgug caggguucca cuuccaaaca ugaguuccag gccgagacaa      360

agaagcuuuu ggacauuguu gcccgguccc uguacucaga aaaagaggug uuuauacggg      420

agcugaucuc caaugccagc gaugccuugg aaaaacugcg ucacaaacug gugucugacg      480

gccaagcacu gccagaaaug gagauucacu ugcagaccaa ugccgagaaa ggcaccauca      540

ccauccagga uacugguauc gggaugacac aggaagagcu gguguccaac cuggggacga      600

uugccagauc ggggucaaag gccuuccugg augcucugca gaaccaggcu gaggccagca      660

gcaagaucau cggccaguuu ggaguggguu ucuacucagc uuucauggug gcugacagag      720

uggaggucua uucccgcucg gcagccccgg ggagccuggg uuaccagugg cuuucagaug      780

guucuggagu guuugaaauc gccgaagcuu cgggaguuag aaccgggaca aaaaucauca      840

uccaccugaa auccgacugc aaggaguuuu ccagcgaggc ccgggugcga gaugugguaa      900

cgaaguacag caacuucguc agcuuccccu uguacuugaa uggaaggcgg augaacaccu      960

ugcaggccau cuggaugaug gaccccaagg auguccguga guggcaacau gaggaguucu     1020

accgcuacgu cgcgcaggcu cacgacaagc cccgcuacac ccugcacuau aagacggacg     1080

caccgcucaa cauccgcagc aucuucuacg ugcccgacau gaaaccgucc auguuugaug     1140

ugagccggga gcugggcucc agcguugcac uguacagccg caaaguccuc auccagacca     1200

aggccacgga cauccugccc aaguggcugc gcuucauccg agguguggug gacagugagg     1260

acauuccccu gaaccucagc cgggagcugc ugcaggagag cgcacucauc aggaaacucc     1320

gggacguuuu acagcagagg cugaucaaau ucuucauuga ccagaguaaa aaagaugcug     1380

agaaguaugc aaaguuuuuu gaagauuacg gccuguucau gcgggagggc auugugaccg     1440

ccaccgagca ggaggucaag gaggacauag caaagcugcu gcgcuacgag uccucggcgc     1500

ugcccuccgg gcagcuaacc agccucucag aauacgccag ccgcaugcgg gccggcaccc     1560

gcaacaucua cuaccugugc gcccccaacc gucaccuggc agagcacuca cccuacuaug     1620

aggccaugaa gaagaaagac acagagguuc ucuucugcuu ugagcaguuu gaugagcuca     1680

cccugcugca ccuucgugag uuugacaaga agaagcugau cucuguggag acggacauag     1740

ucguggauca cuacaaggag gagaaguuug aggacagguc cccagccgcc gagugccuau     1800

cagagaagga gacggaggag cucauggccu ggaugagaaa ugugcugggg ucgcguguca     1860

ccaacgugaa ggugacccuc cgacuggaca cccacccugc cauggucacc gugcuggaga     1920

ugggggcugc ccgccacuuc cugcgcaugc agcagcuggc caagacccag gaggagcgcg     1980

cacagcuccu gcagcccacg cuggagauca accccaggca cgcgcucauc aagaagcuga     2040

aucagcugcg cgcaagcgag ccuggccugg cucagcugcu gguggaucag auauacgaga     2100

acgccaugau ugcugcugga cuuguugacg acccuagggc cauggugggc cgcuugaaug     2160

agcugcuugu caaggcccug gagcgacacu gaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  3878
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (wt)

<400>  3878
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaauca gcagucuucc aacccaauua uuuaagugcu      120

gcuuuuguga uuucuugaag gugaagaugc acaccauguc cuccucgcau cucuucuacc      180

uggcgcugug ccugcucacc uucaccagcu cugccacggc uggaccggag acgcucugcg      240

gggcugagcu gguggaugcu cuucaguucg uguguggaga caggggcuuu uauuucaaca      300

agcccacagg guauggcucc agcagucgga gggcgccuca gacaggcauc guggaugagu      360

gcugcuuccg gagcugugau cuaaggaggc uggagaugua uugcgcaccc cucaagccug      420

ccaagucagc ucgcucuguc cgugcccagc gccacaccga caugcccaag acccagaagg      480

aaguacauuu gaagaacgca aguagaggga gugcaggaaa caagaacuac aggauguagg      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  3879
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (wt)

<400>  3879
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaucccaa uggggaaguc gaugcuggug cuucucaccu      120

ucuuggccuu cgccucgugc ugcauugcug cuuaccgccc cagugagacc cugugcggcg      180

gggagcuggu ggacacccuc caguucgucu guggggaccg cggcuucuac uucagcaggc      240

ccgcaagccg ugugagccgu cgcagccgug gcaucguuga ggagugcugu uuccgcagcu      300

gugaccuggc ccuccuggag acguacugug cuacccccgc caaguccgag agggacgugu      360

cgaccccucc gaccgugcuu ccggacaacu uccccagaua ccccgugggc aaguucuucc      420

aauaugacac cuggaagcag uccacccagc gccugcgcag gggccugccu gcccuccugc      480

gugcccgccg gggucacgug cucgccaagg agcucgaggc guucagggag gccaaacguc      540

accguccccu gauugcucua cccacccaag accccgccca cgggggcgcc cccccagaga      600

uggccagcaa ucggaaguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  3880
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (wt)

<400>  3880
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccacaagcgc cuucggucca guugccuucu      120

cccuggggcu gcuccuggug uugccugcug ccuucccugc cccaguaccc ccaggagaag      180

auuccaaaga uguagccgcc ccacacagac agccacucac cucuucagaa cgaauugaca      240

aacaaauucg guacauccuc gacggcaucu cagcccugag aaaggagaca uguaacaaga      300

guaacaugug ugaaagcagc aaagaggcac uggcagaaaa caaccugaac cuuccaaaga      360

uggcugaaaa agauggaugc uuccaaucug gauucaauga ggagacuugc cuggugaaaa      420

ucaucacugg ucuuuuggag uuugagguau accuagagua ccuccagaac agauuugaga      480

guagugagga acaagccaga gcugugcaga ugaguacaaa aguccugauc caguuccugc      540

agaaaaaggc aaagaaucua gaugcaauaa ccaccccuga cccaaccaca aaugccagcc      600

ugcugacgaa gcugcaggca cagaaccagu ggcugcagga caugacaacu caucucauuc      660

ugcgcagcuu uaaggaguuc cugcagucca gccugagggc ucuucggcaa auguagggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  3881
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (wt)

<400>  3881
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccuugcuuu ggcugagagg auuucuguug gcaaguugcu      120

ggauuauagu gaggaguucc cccaccccag gauccgaggg gcacagcgcg gcccccgacu      180

guccguccug ugcgcuggcc gcccucccaa aggauguacc caacucucag ccagagaugg      240

uggaggccgu caagaagcac auuuuaaaca ugcugcacuu gaagaagaga cccgauguca      300

cccagccggu acccaaggcg gcgcuucuga acgcgaucag aaagcuucau gugggcaaag      360

ucggggagaa cggguaugug gagauagagg augacauugg aaggagggca gaaaugaaug      420

aacuuaugga gcagaccucg gagaucauca cguuugccga gucaggaaca gccaggaaga      480

cgcugcacuu cgagauuucc aaggaaggca gugaccuguc agugguggag cgugcagaag      540

ucuggcucuu ccuaaaaguc cccaaggcca acaggaccag gaccaaaguc accauccgcc      600

ucuuccagca gcagaagcac ccgcagggca gcuuggacac aggggaagag gccgaggaag      660

ugggcuuaaa gggggagagg agugaacugu ugcucucuga aaaaguagua gacgcucgga      720

agagcaccug gcaugucuuc ccugucucca gcagcaucca gcgguugcug gaccagggca      780

agagcucccu ggacguucgg auugccugug agcagugcca ggagaguggc gccagcuugg      840

uucuccuggg caagaagaag aagaaagaag aggaggggga agggaaaaag aagggcggag      900

gugaaggugg ggcaggagca gaugaggaaa aggagcaguc gcacagaccu uuccucaugc      960

ugcaggcccg gcagucugaa gaccacccuc aucgccggcg ucggcggggc uuggagugug     1020

auggcaaggu caacaucugc uguaagaaac aguucuuugu caguuucaag gacaucggcu     1080

ggaaugacug gaucauugcu cccucuggcu aucaugccaa cuacugcgag ggugagugcc     1140

cgagccauau agcaggcacg uccggguccu cacuguccuu ccacucaaca gucaucaacc     1200

acuaccgcau gcggggccau agccccuuug ccaaccucaa aucgugcugu gugcccacca     1260

agcugagacc cauguccaug uuguacuaug augaugguca aaacaucauc aaaaaggaca     1320

uucagaacau gaucguggag gagugugggu gcucauaggg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  3882
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (wt)

<400>  3882
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacgggcugc ccggucgggc gcugggggcc gccugccuuc      120

ugcugcuggc ggccggcugg cuggggccug aggccugggg cucacccacg cccccgccga      180

cgccugccgc gccgccgcca cccccgccac ccggaucccc ggguggcucg caggacaccu      240

guacgucgug cggcggcuuc cggcggccag aggagcucgg ccgaguggac ggcgacuucc      300

uggaggcggu gaagcggcac aucuugagcc gccugcagau gcggggccgg cccaacauca      360

cgcacgccgu gccuaaggcc gccaugguca cggcccugcg caagcugcac gcgggcaagg      420

ugcgcgagga cggccgcgug gagaucccgc accucgacgg ccacgccagc ccgggcgccg      480

acggccagga gcgcguuucc gaaaucauca gcuucgccga gacagauggc cucgccuccu      540

cccggguccg ccuauacuuc uucaucucca acgaaggcaa ccagaaccug uuuguggucc      600

aggccagccu guggcuuuac cugaaacucc ugcccuacgu ccuggagaag ggcagccggc      660

ggaaggugcg ggucaaagug uacuuccagg agcagggcca cggugacagg uggaacaugg      720

uggagaagag gguggaccuc aagcgcagcg gcuggcauac cuucccacuc acggaggcca      780

uccaggccuu guuugagcgg ggcgagcggc gacucaaccu agacgugcag ugugacagcu      840

gccaggagcu ggccguggug ccgguguucg uggacccagg cgaagagucg caccggcccu      900

uugugguggu gcaggcucgg cugggcgaca gcaggcaccg cauucgcaag cgaggccugg      960

agugcgaugg ccggaccaac cucuguugca ggcaacaguu cuucauugac uuccgccuca     1020

ucggcuggaa cgacuggauc auagcaccca ccggcuacua cgggaacuac ugugagggca     1080

gcugcccagc cuaccuggca gggguccccg gcucugccuc cuccuuccac acggcugugg     1140

ugaaccagua ccgcaugcgg ggucugaacc ccggcacggu gaacuccugc ugcauuccca     1200

ccaagcugag caccaugucc augcuguacu ucgaugauga guacaacauc gucaagcggg     1260

acgugcccaa caugauugug gaggagugcg gcugcgccug aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  3883
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (wt)

<400>  3883
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucucagag uccuucuguu aacagccuug accuuauguc      120

auggguucaa cuuggacacu gaaaacgcaa ugaccuucca agagaacgca aggggcuucg      180

ggcagagcgu gguccagcuu cagggaucca gggugguggu uggagccccc caggagauag      240

uggcugccaa ccaaaggggc agccucuacc agugcgacua cagcacaggc ucaugcgagc      300

ccauccgccu gcaggucccc guggaggccg ugaacauguc ccugggccug ucccuggcag      360

ccaccaccag ccccccucag cugcuggccu guggucccac cgugcaccag acuugcagug      420

agaacacgua ugugaaaggg cucugcuucc uguuuggauc caaccuacgg cagcagcccc      480

agaaguuccc agaggcccuc cgaggguguc cucaagagga uagugacauu gccuucuuga      540

uugauggcuc ugguagcauc aucccacaug acuuucggcg gaugaaggag uuugucucaa      600

cugugaugga gcaauuaaaa aaguccaaaa ccuuguucuc uuugaugcag uacucugaag      660

aauuccggau ucacuuuacc uucaaagagu uccagaacaa cccuaaccca agaucacugg      720

ugaagccaau aacgcagcug cuugggcgga cacacacggc cacgggcauc cgcaaagugg      780

uacgagagcu guuuaacauc accaacggag cccgaaagaa ugccuuuaag auccuaguug      840

ucaucacgga uggagaaaag uuuggcgauc ccuugggaua ugaggauguc aucccugagg      900

cagacagaga gggagucauu cgcuacguca uugggguggg agaugccuuc cgcagugaga      960

aaucccgcca agagcuuaau accaucgcau ccaagccgcc ucgugaucac guguuccagg     1020

ugaauaacuu ugaggcucug aagaccauuc agaaccagcu ucgggagaag aucuuugcga     1080

ucgaggguac ucagacagga aguagcagcu ccuuugagca ugagaugucu caggaaggcu     1140

ucagcgcugc caucaccucu aauggccccu ugcugagcac uguggggagc uaugacuggg     1200

cugguggagu cuuucuauau acaucaaagg agaaaagcac cuucaucaac augaccagag     1260

uggauucaga caugaaugau gcuuacuugg guuaugcugc cgccaucauc uuacggaacc     1320

gggugcaaag ccugguucug ggggcaccuc gauaucagca caucggccug guagcgaugu     1380

ucaggcagaa cacuggcaug ugggagucca acgcuaaugu caagggcacc cagaucggcg     1440

ccuacuucgg ggccucccuc ugcuccgugg acguggacag caacggcagc accgaccugg     1500

uccucaucgg ggccccccau uacuacgagc agacccgagg gggccaggug uccgugugcc     1560

ccuugcccag ggggagggcu cgguggcagu gugaugcugu ucucuacggg gagcagggcc     1620

aacccugggg ccgcuuuggg gcagcccuaa cagugcuggg ggacguaaau ggggacaagc     1680

ugacggacgu ggccauuggg gccccaggag aggaggacaa ccggggugcu guuuaccugu     1740

uucacggaac cucaggaucu ggcaucagcc ccucccauag ccagcggaua gcaggcucca     1800

agcucucucc caggcuccag uauuuugguc agucacugag ugggggccag gaccucacaa     1860

uggauggacu gguagaccug acuguaggag cccaggggca cgugcugcug cucagguccc     1920

agccaguacu gagagucaag gcaaucaugg aguucaaucc cagggaagug gcaaggaaug     1980

uauuugagug uaaugaucag guggugaaag gcaaggaagc cggagagguc agagucugcc     2040

uccaugucca gaagagcaca cgggaucggc uaagagaagg acagauccag aguguuguga     2100

cuuaugaccu ggcucuggac uccggccgcc cacauucccg cgccgucuuc aaugagacaa     2160

agaacagcac acgcagacag acacaggucu uggggcugac ccagacuugu gagacccuga     2220

aacuacaguu gccgaauugc aucgaggacc cagugagccc cauugugcug cgccugaacu     2280

ucucucuggu gggaacgcca uugucugcuu ucgggaaccu ccggccagug cuggcggagg     2340

augcucagag acucuucaca gccuuguuuc ccuuugagaa gaauuguggc aaugacaaca     2400

ucugccagga ugaccucagc aucaccuuca guuucaugag ccuggacugc cucguggugg     2460

gugggccccg ggaguucaac gugacaguga cugugagaaa ugauggugag gacuccuaca     2520

ggacacaggu caccuucuuc uucccgcuug accuguccua ccggaaggug uccacgcucc     2580

agaaccagcg cucacagcga uccuggcgcc uggccuguga gucugccucc uccaccgaag     2640

ugucuggggc cuugaagagc accagcugca gcauaaacca ccccaucuuc ccggaaaacu     2700

cagaggucac cuuuaauauc acguuugaug uagacucuaa ggcuucccuu ggaaacaaac     2760

ugcuccucaa ggccaaugug accagugaga acaacaugcc cagaaccaac aaaaccgaau     2820

uccaacugga gcugccggug aaauaugcug ucuacauggu ggucaccagc cauggggucu     2880

ccacuaaaua ucucaacuuc acggccucag agaauaccag ucgggucaug cagcaucaau     2940

aucaggucag caaccugggg cagaggagcc uccccaucag ccugguguuc uuggugcccg     3000

uccggcugaa ccagacuguc auaugggacc gcccccaggu caccuucucc gagaaccucu     3060

cgaguacgug ccacaccaag gagcgcuugc ccucucacuc cgacuuucug gcugagcuuc     3120

ggaaggcccc cguggugaac ugcuccaucg cugucugcca gagaauccag ugugacaucc     3180

cguucuuugg cauccaggaa gaauucaaug cuacccucaa aggcaaccuc ucguuugacu     3240

gguacaucaa gaccucgcau aaccaccucc ugaucgugag cacagcugag aucuuguuua     3300

acgauuccgu guucacccug cugccgggac agggggcguu ugugaggucc cagacggaga     3360

ccaaagugga gccguucgag guccccaacc cccugccgcu caucgugggc agcucugucg     3420

ggggacugcu gcuccuggcc cucaucaccg ccgcgcugua caagcucggc uucuucaagc     3480

ggcaauacaa ggacaugaug agugaagggg gucccccggg ggccgaaccc caguagggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  3884
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (wt)

<400>  3884
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucccuga agacgcuucc auuucugcuc uuacuccaug      120

ugcagauuuc caaggccuuu ccuguaucuu cuaaagagaa aaauacaaaa acuguucagg      180

acuaccugga aaaguucuac caauuaccaa gcaaccagua ucagucuaca aggaagaaug      240

gcacuaaugu gaucguugaa aagcuuaaag aaaugcagcg auuuuuuggg uugaauguga      300

cggggaagcc aaaugaggaa acucuggaca ugaugaaaaa gccucgcugu ggagugccug      360

acaguggugg uuuuauguua accccaggaa accccaagug ggaacgcacu aacuugaccu      420

acaggauucg aaacuauacc ccacagcugu cagaggcuga gguagaaaga gcuaucaagg      480

augccuuuga acucuggagu guugcaucac cucucaucuu caccaggauc ucacagggag      540

aggcagauau caacauugcu uuuuaccaaa gagaucacgg ugacaauucu ccauuugaug      600

gacccaaugg aauccuugcu caugccuuuc agccaggcca agguauugga ggagaugcuc      660

auuuugaugc cgaagaaaca uggaccaaca ccuccgcaaa uuacaacuug uuucuuguug      720

cugcucauga auuuggccau ucuuuggggc ucgcucacuc cucugacccu ggugccuuga      780

uguaucccaa cuaugcuuuc agggaaacca gcaacuacuc acucccucaa gaugacaucg      840

auggcauuca ggccaucuau ggacuuucaa gcaacccuau ccaaccuacu ggaccaagca      900

cacccaaacc cugugacccc aguuugacau uugaugcuau caccacacuc cguggagaaa      960

uacuuuucuu uaaagacagg uacuucugga gaaggcaucc ucagcuacaa agagucgaaa     1020

ugaauuuuau uucucuauuc uggccauccc uuccaacugg uauacaggcu gcuuaugaag     1080

auuuugacag agaccucauu uuccuauuua aaggcaacca auacugggcu cugaguggcu     1140

augauauucu gcaagguuau cccaaggaua uaucaaacua uggcuucccc agcagcgucc     1200

aagcaauuga cgcagcuguu uucuacagaa guaaaacaua cuucuuugua aaugaccaau     1260

ucuggagaua ugauaaccaa agacaauuca uggagccagg uuaucccaaa agcauaucag     1320

gugccuuucc aggaauagag aguaaaguug augcaguuuu ccagcaagaa cauuucuucc     1380

augucuucag uggaccaaga uauuacgcau uugaucuuau ugcucagaga guuaccagag     1440

uugcaagagg caauaaaugg cuuaacugua gauauggcug aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  3885
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (wt)

<400>  3885
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccucuggc agccccuggu ccuggugcuc cuggugcugg      120

gcugcugcuu ugcugccccc agacagcgcc aguccacccu ugugcucuuc ccuggagacc      180

ugagaaccaa ucucaccgac aggcagcugg cagaggaaua ccuguaccgc uaugguuaca      240

cucggguggc agagaugcgu ggagagucga aaucucuggg gccugcgcug cugcuucucc      300

agaagcaacu gucccugccc gagaccggug agcuggauag cgccacgcug aaggccaugc      360

gaaccccacg gugcgggguc ccagaccugg gcagauucca aaccuuugag ggcgaccuca      420

aguggcacca ccacaacauc accuauugga uccaaaacua cucggaagac uugccgcggg      480

cggugauuga cgacgccuuu gcccgcgccu ucgcacugug gagcgcggug acgccgcuca      540

ccuucacucg cguguacagc cgggacgcag acaucgucau ccaguuuggu gucgcggagc      600

acggagacgg guaucccuuc gacgggaagg acgggcuccu ggcacacgcc uuuccuccug      660

gccccggcau ucagggagac gcccauuucg acgaugacga guuguggucc cugggcaagg      720

gcgucguggu uccaacucgg uuuggaaacg cagauggcgc ggccugccac uuccccuuca      780

ucuucgaggg ccgcuccuac ucugccugca ccaccgacgg ucgcuccgac ggcuugcccu      840

ggugcaguac cacggccaac uacgacaccg acgaccgguu uggcuucugc cccagcgaga      900

gacucuacac ccaggacggc aaugcugaug ggaaacccug ccaguuucca uucaucuucc      960

aaggccaauc cuacuccgcc ugcaccacgg acggucgcuc cgacggcuac cgcuggugcg     1020

ccaccaccgc caacuacgac cgggacaagc ucuucggcuu cugcccgacc cgagcugacu     1080

cgacggugau ggggggcaac ucggcggggg agcugugcgu cuuccccuuc acuuuccugg     1140

guaaggagua cucgaccugu accagcgagg gccgcggaga ugggcgccuc uggugcgcua     1200

ccaccucgaa cuuugacagc gacaagaagu ggggcuucug cccggaccaa ggauacaguu     1260

uguuccucgu ggcggcgcau gaguucggcc acgcgcuggg cuuagaucau uccucagugc     1320

cggaggcgcu cauguacccu auguaccgcu ucacugaggg gccccccuug cauaaggacg     1380

acgugaaugg cauccggcac cucuaugguc cucgcccuga accugagcca cggccuccaa     1440

ccaccaccac accgcagccc acggcucccc cgacggucug ccccaccgga ccccccacug     1500

uccaccccuc agagcgcccc acagcuggcc ccacaggucc ccccucagcu ggccccacag     1560

guccccccac ugcuggcccu ucuacggcca cuacugugcc uuugaguccg guggacgaug     1620

ccugcaacgu gaacaucuuc gacgccaucg cggagauugg gaaccagcug uauuuguuca     1680

aggaugggaa guacuggcga uucucugagg gcagggggag ccggccgcag ggccccuucc     1740

uuaucgccga caaguggccc gcgcugcccc gcaagcugga cucggucuuu gaggagcggc     1800

ucuccaagaa gcuuuucuuc uucucugggc gccaggugug gguguacaca ggcgcgucgg     1860

ugcugggccc gaggcgucug gacaagcugg gccugggagc cgacguggcc caggugaccg     1920

gggcccuccg gaguggcagg gggaagaugc ugcuguucag cgggcggcgc cucuggaggu     1980

ucgacgugaa ggcgcagaug guggaucccc ggagcgccag cgagguggac cggauguucc     2040

ccggggugcc uuuggacacg cacgacgucu uccaguaccg agagaaagcc uauuucugcc     2100

aggaccgcuu cuacuggcgc gugaguuccc ggagugaguu gaaccaggug gaccaagugg     2160

gcuacgugac cuaugacauc cugcagugcc cugaggacua gggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  3886
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (wt)

<400>  3886
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauccagggg uccuggcugc cuuccucuuc uugagcugga      120

cucauugucg ggcccugccc cuucccagug guggugauga agaugauuug ucugaggaag      180

accuccaguu ugcagagcgc uaccugagau cauacuacca uccuacaaau cucgcgggaa      240

uccugaagga gaaugcagca agcuccauga cugagaggcu ccgagaaaug cagucuuucu      300

ucggcuuaga ggugacuggc aaacuugacg auaacaccuu agaugucaug aaaaagccaa      360

gaugcggggu uccugaugug ggugaauaca auguuuuccc ucgaacucuu aaauggucca      420

aaaugaauuu aaccuacaga auugugaauu acaccccuga uaugacucau ucugaagucg      480

aaaaggcauu caaaaaagcc uucaaaguuu gguccgaugu aacuccucug aauuuuacca      540

gacuucacga uggcauugcu gacaucauga ucucuuuugg aauuaaggag cauggcgacu      600

ucuacccauu ugaugggccc ucuggccugc uggcucaugc uuuuccuccu gggccaaauu      660

auggaggaga ugcccauuuu gaugaugaug aaaccuggac aaguaguucc aaaggcuaca      720

acuuguuucu uguugcugcg caugaguucg gccacuccuu aggucuugac cacuccaagg      780

acccuggagc acucauguuu ccuaucuaca ccuacaccgg caaaagccac uuuaugcuuc      840

cugaugacga uguacaaggg auccagucuc ucuauggucc aggagaugaa gaccccaacc      900

cuaaacaucc aaaaacgcca gacaaaugug acccuuccuu aucccuugau gccauuacca      960

gucuccgagg agaaacaaug aucuuuaaag acagauucuu cuggcgccug cauccucagc     1020

agguugaugc ggagcuguuu uuaacgaaau cauuuuggcc agaacuuccc aaccguauug     1080

augcugcaua ugagcacccu ucucaugacc ucaucuucau cuucagaggu agaaaauuuu     1140

gggcucuuaa ugguuaugac auucuggaag guuaucccaa aaaaauaucu gaacuggguc     1200

uuccaaaaga aguuaagaag auaagugcag cuguucacuu ugaggauaca ggcaagacuc     1260

uccuguucuc aggaaaccag gucuggagau augaugauac uaaccauauu auggauaaag     1320

acuauccgag acuaauagaa gaagacuucc caggaauugg ugauaaagua gaugcugucu     1380

augagaaaaa ugguuauauc uauuuuuuca acggacccau acaguuugaa uacagcaucu     1440

ggaguaaccg uauuguucgc gucaugccag caaauuccau uuuguggugu uaaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  3887
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (wt)

<400>  3887
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacuccaa acaccacaga ggacuaugac acgaccacag      120

aguuugacua uggggaugca acuccgugcc agaaggugaa cgagagggcc uuuggggccc      180

aacugcugcc cccucuguac uccuugguau uugucauugg ccugguugga aacauccugg      240

ugguccuggu ccuugugcaa uacaagaggc uaaaaaacau gaccagcauc uaccuccuga      300

accuggccau uucugaccug cucuuccugu ucacgcuucc cuucuggauc gacuacaagu      360

ugaaggauga cuggguuuuu ggugaugcca uguguaagau ccucucuggg uuuuauuaca      420

caggcuugua cagcgagauc uuuuucauca uccugcugac gauugacagg uaccuggcca      480

ucguccacgc cguguuugcc uugcgggcac ggaccgucac uuuugguguc aucaccagca      540

ucaucauuug ggcccuggcc aucuuggcuu ccaugccagg cuuauacuuu uccaagaccc      600

aaugggaauu cacucaccac accugcagcc uucacuuucc ucacgaaagc cuacgagagu      660

ggaagcuguu ucaggcucug aaacugaacc ucuuugggcu gguauugccu uuguugguca      720

ugaucaucug cuacacaggg auuauaaaga uucugcuaag acgaccaaau gagaagaaau      780

ccaaagcugu ccguuugauu uuugucauca ugaucaucuu uuuucucuuu uggacccccu      840

acaauuugac uauacuuauu ucuguuuucc aagacuuccu guucacccau gagugugagc      900

agagcagaca uuuggaccug gcugugcaag ugacggaggu gaucgccuac acgcacugcu      960

gugucaaccc agugaucuac gccuucguug gugagagguu ccggaaguac cugcggcagu     1020

uguuccacag gcguguggcu gugcaccugg uuaaauggcu ccccuuccuc uccguggaca     1080

ggcuggagag ggucagcucc acaucucccu ccacagggga gcaugaacuc ucugcugggu     1140

ucugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  3888
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (wt)

<400>  3888
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aggaccuugg cuugccugcu gcuccucggc ugcggauacc      120

ucgcccaugu ucuggccgag gaagccgaga ucccccgcga ggugaucgag aggcuggccc      180

gcagucagau ccacagcauc cgggaccucc agcgacuccu ggagauagac uccguaggga      240

gugaggauuc uuuggacacc agccugagag cucacggggu ccaugccacu aagcaugugc      300

ccgagaagcg gccccugccc auucggagga agagaagcau cgaggaagcu guccccgcug      360

ucugcaagac caggacgguc auuuacgaga uuccucggag ucaggucgac cccacguccg      420

ccaacuuccu gaucuggccc ccgugcgugg aggugaaacg cugcaccggc ugcugcaaca      480

cgagcagugu caagugccag cccucccgcg uccaccaccg cagcgucaag guggccaagg      540

uggaauacgu caggaagaag ccaaaauuaa aagaagucca ggugagguua gaggagcauu      600

uggagugcgc cugcgcgacc acaagccuga auccggauua ucgggaagag gacacgggaa      660

ggccuaggga gucagguaaa aaacggaaaa gaaaaagguu aaaacccacc uaaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  3889
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (wt)

<400>  3889
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaucgcugcu gggcgcucuu ccugucucuc ugcugcuacc      120

ugcgucuggu cagcgccgag ggggacccca uucccgagga gcuuuaugag augcugagug      180

accacucgau ccgcuccuuu gaugaucucc aacgccugcu gcacggagac cccggagagg      240

aagauggggc cgaguuggac cugaacauga cccgcuccca cucuggaggc gagcuggaga      300

gcuuggcucg uggaagaagg agccuggguu cccugaccau ugcugagccg gccaugaucg      360

ccgagugcaa gacgcgcacc gagguguucg agaucucccg gcgccucaua gaccgcacca      420

acgccaacuu ccuggugugg ccgcccugug uggaggugca gcgcugcucc ggcugcugca      480

acaaccgcaa cgugcagugc cgccccaccc aggugcagcu gcgaccuguc caggugagaa      540

agaucgagau ugugcggaag aagccaaucu uuaagaaggc cacggugacg cuggaagacc      600

accuggcaug caagugugag acaguggcag cugcacggcc ugugacccga agcccggggg      660

guucccagga gcagcgagcc aaaacgcccc aaacucgggu gaccauucgg acggugcgag      720

uccgccggcc ccccaagggc aagcaccgga aauucaagca cacgcaugac aagacggcac      780

ugaaggagac ccuuggagcc uagggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  3890
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (wt)

<400>  3890
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccucuucg ggcuucuccu gcugacaucu gcccuggccg      120

gccagagaca ggggacucag gcggaaucca accugaguag uaaauuccag uuuuccagca      180

acaaggaaca gaacggagua caagauccuc agcaugagag aauuauuacu gugucuacua      240

auggaaguau ucacagccca agguuuccuc auacuuaucc aagaaauacg gucuugguau      300

ggagauuagu agcaguagag gaaaauguau ggauacaacu uacguuugau gaaagauuug      360

ggcuugaaga cccagaagau gacauaugca aguaugauuu uguagaaguu gaggaaccca      420

gugauggaac uauauuaggg cgcuggugug guucugguac uguaccagga aaacagauuu      480

cuaaaggaaa ucaaauuagg auaagauuug uaucugauga auauuuuccu ucugaaccag      540

gguucugcau ccacuacaac auugucaugc cacaauucac agaagcugug aguccuucag      600

ugcuaccccc uucagcuuug ccacuggacc ugcuuaauaa ugcuauaacu gccuuuagua      660

ccuuggaaga ccuuauucga uaucuugaac cagagagaug gcaguuggac uuagaagauc      720

uauauaggcc aacuuggcaa cuucuuggca aggcuuuugu uuuuggaaga aaauccagag      780

ugguggaucu gaaccuucua acagaggagg uaagauuaua cagcugcaca ccucguaacu      840

ucucaguguc cauaagggaa gaacuaaaga gaaccgauac cauuuucugg ccagguuguc      900

uccugguuaa acgcuguggu gggaacugug ccuguugucu ccacaauugc aaugaauguc      960

aauguguccc aagcaaaguu acuaaaaaau accacgaggu ccuucaguug agaccaaaga     1020

ccggugucag gggauugcac aaaucacuca ccgacguggc ccuggagcac caugaggagu     1080

gugacugugu gugcagaggg agcacaggag gauagggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  3891
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (wt)

<400>  3891
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccggcuca ucuuugucua cacucuaauc ugcgcaaacu      120

uuugcagcug ucgggacacu ucugcaaccc cgcagagcgc auccaucaaa gcuuugcgca      180

acgccaaccu caggcgagau gacuuguacc gaagagauga gaccauccag gugaaaggaa      240

acggcuacgu gcagaguccu agauucccga acagcuaccc caggaaccug cuccugacau      300

ggcggcuuca cucucaggag aauacacgga uacagcuagu guuugacaau caguuuggau      360

uagaggaagc agaaaaugau aucuguaggu augauuuugu ggaaguugaa gauauauccg      420

aaaccaguac cauuauuaga ggacgauggu guggacacaa ggaaguuccu ccaaggauaa      480

aaucaagaac gaaccaaauu aaaaucacau ucaaguccga ugacuacuuu guggcuaaac      540

cuggauucaa gauuuauuau ucuuugcugg aagauuucca acccgcagca gcuucagaga      600

ccaacuggga aucugucaca agcucuauuu cagggguauc cuauaacucu ccaucaguaa      660

cggaucccac ucugauugcg gaugcucugg acaaaaaaau ugcagaauuu gauacagugg      720

aagaucugcu caaguacuuc aauccagagu cauggcaaga agaucuugag aauauguauc      780

uggacacccc ucgguaucga ggcaggucau accaugaccg gaagucaaaa guugaccugg      840

auaggcucaa ugaugaugcc aagcguuaca guugcacucc caggaauuac ucggucaaua      900

uaagagaaga gcugaaguug gccaaugugg ucuucuuucc acguugccuc cucgugcagc      960

gcuguggagg aaauuguggc uguggaacug ucaacuggag guccugcaca ugcaauucag     1020

ggaaaaccgu gaaaaaguau caugagguau uacaguuuga gccuggccac aucaagagga     1080

gggguagagc uaagaccaug gcucuaguug acauccaguu ggaucaccau gaacgaugug     1140

auuguaucug cagcucaaga ccaccucgau aaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  3892
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (wt)

<400>  3892
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccaca gcaaguuucc cgccgccggg augagccgcc      120

cccuggacac cagccugcgc cucaagaccu ucagcuccaa gagcgaguac cagcuggugg      180

ugaacgcagu gcgcaagcug caggagagcg gcuucuacug gagcgcagug accggcggcg      240

aggcgaaccu gcugcucagu gccgagcccg ccggcaccuu ucugauccgc gacagcucgg      300

accagcgcca cuucuucacg cucagcguca agacccaguc ugggaccaag aaccugcgca      360

uccaguguga ggggggcagc uucucucugc agagcgaucc ccggagcacg cagcccgugc      420

cccgcuucga cugcgugcuc aagcuggugc accacuacau gccgcccccu ggagcccccu      480

ccuuccccuc gccaccuacu gaacccuccu ccgaggugcc cgagcagccg ucugcccagc      540

cacucccugg gagucccccc agaagagccu auuacaucua cuccgggggc gagaagaucc      600

cccugguguu gagccggccc cucuccucca acguggccac ucuucagcau cucugucgga      660

agaccgucaa cggccaccug gacuccuaug agaaagucac ccagcugccg gggcccauuc      720

gggaguuccu ggaccaguac gaugccccgc uuuaaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  3893
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (wt)

<400>  3893
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guccccucgg cuggacagcu cgcccuguuc gcucugggua      120

uuguguuggc ugcgugccag gccuuggaga acagcacguc cccgcugagu gcagacccgc      180

ccguggcugc agcaguggug ucccauuuua augacugccc agauucccac acucaguucu      240

gcuuccaugg aaccugcagg uuuuuggugc aggaggacaa gccagcaugu gucugccauu      300

cuggguacgu uggugcacgc ugugagcaug cggaccuccu ggccguggug gcugccagcc      360

agaagaagca ggccaucacc gccuuggugg uggucuccau cguggcccug gcuguccuua      420

ucaucacaug ugugcugaua cacugcugcc agguccgaaa acacugugag uggugccggg      480

cccucaucug ccggcacgag aagcccagcg cccuccugaa gggaagaacc gcuugcugcc      540

acucagaaac aguggucuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  3894
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (wt)

<400>  3894
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccgcccuccg ggcugcggcu gcugccgcug cugcuaccgc      120

ugcuguggcu acuggugcug acgccuggcc ggccggccgc gggacuaucc accugcaaga      180

cuaucgacau ggagcuggug aagcggaagc gcaucgaggc cauccgcggc cagauccugu      240

ccaagcugcg gcucgccagc cccccgagcc agggggaggu gccgcccggc ccgcugcccg      300

aggccgugcu cgcccuguac aacagcaccc gcgaccgggu ggccggggag agugcagaac      360

cggagcccga gccugaggcc gacuacuacg ccaaggaggu cacccgcgug cuaauggugg      420

aaacccacaa cgaaaucuau gacaaguuca agcagaguac acacagcaua uauauguucu      480

ucaacacauc agagcuccga gaagcgguac cugaacccgu guugcucucc cgggcagagc      540

ugcgucugcu gaggcucaag uuaaaagugg agcagcacgu ggagcuguac cagaaauaca      600

gcaacaauuc cuggcgauac cucagcaacc ggcugcuggc acccagcgac ucgccagagu      660

gguuaucuuu ugaugucacc ggaguugugc ggcagugguu gagccgugga ggggaaauug      720

agggcuuucg ccuuagcgcc cacugcuccu gugacagcag ggauaacaca cugcaagugg      780

acaucaacgg guucacuacc ggccgccgag gugaccuggc caccauucau ggcaugaacc      840

ggccuuuccu gcuucucaug gccaccccgc uggagagggc ccagcaucug caaagcuccc      900

ggcaccgccg agcccuggac accaacuauu gcuucagcuc cacggagaag aacugcugcg      960

ugcggcagcu guacauugac uuccgcaagg accucggcug gaaguggauc cacgagccca     1020

agggcuacca ugccaacuuc ugccucgggc ccugccccua cauuuggagc cuggacacgc     1080

aguacagcaa gguccuggcc cuguacaacc agcauaaccc gggcgccucg gcggcgccgu     1140

gcugcgugcc gcaggcgcug gagccgcugc ccaucgugua cuacgugggc cgcaagccca     1200

agguggagca gcuguccaac augaucgugc gcuccugcaa gugcagcuga ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  3895
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (wt)

<400>  3895
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugug ugcugagcgc uuuucugauc cugcaucugg      120

ucacggucgc gcucagccug ucuaccugca gcacacucga uauggaccag uucaugcgca      180

agaggaucga ggcgauccgc gggcagaucc ugagcaagcu gaagcucacc agucccccag      240

aagacuaucc ugagcccgag gaaguccccc cggaggugau uuccaucuac aacagcacca      300

gggacuugcu ccaggagaag gcgagccgga gggcggccgc cugcgagcgc gagaggagcg      360

acgaagagua cuacgccaag gagguuuaca aaauagacau gccgcccuuc uuccccuccg      420

aaaaugccau cccgcccacu uucuacagac ccuacuucag aauuguucga uuugacgucu      480

cagcaaugga gaagaaugcu uccaauuugg ugaaagcaga guucagaguc uuucguuugc      540

agaacccaaa agccagagug ccugaacaac ggauugagcu auaucagauu cucaagucca      600

aagauuuaac aucuccaacc cagcgcuaca ucgacagcaa aguugugaaa acaagagcag      660

aaggcgaaug gcucuccuuc gauguaacug augcuguuca ugaauggcuu caccauaaag      720

acaggaaccu gggauuuaaa auaagcuuac acugucccug cugcacuuuu guaccaucua      780

auaauuacau caucccaaau aaaagugaag aacuagaagc aagauuugca gguauugaug      840

gcaccuccac auauaccagu ggugaucaga aaacuauaaa guccacuagg aaaaaaaaca      900

gugggaagac cccacaucuc cugcuaaugu uauugcccuc cuacagacuu gagucacaac      960

agaccaaccg gcggaagaag cgugcuuugg augcggccua uugcuuuaga aaugugcagg     1020

auaauugcug ccuacgucca cuuuacauug auuucaagag ggaucuaggg uggaaaugga     1080

uacacgaacc caaaggguac aaugccaacu ucugugcugg agcaugcccg uauuuaugga     1140

guucagacac ucagcacagc aggguccuga gcuuauauaa uaccauaaau ccagaagcau     1200

cugcuucucc uugcugcgug ucccaagauu uagaaccucu aaccauucuc uacuacauug     1260

gcaaaacacc caagauugaa cagcuuucua auaugauugu aaagucuugc aaaugcagcu     1320

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  3896
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (wt)

<400>  3896
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacu ugcaaagggc ucuggugguc cuggcccugc      120

ugaacuuugc cacggucagc cucucucugu ccacuugcac caccuuggac uucggccaca      180

ucaagaagaa gaggguggaa gccauuaggg gacagaucuu gagcaagcuc aggcucacca      240

gccccccuga gccaacggug augacccacg uccccuauca gguccuggcc cuuuacaaca      300

gcacccggga gcugcuggag gagaugcaug gggagaggga ggaaggcugc acccaggaaa      360

acaccgaguc ggaauacuau gccaaagaaa uccauaaauu cgacaugauc caggggcugg      420

cggagcacaa cgaacuggcu gucugcccua aaggaauuac cuccaagguu uuccgcuuca      480

auguguccuc aguggagaaa aauagaacca accuauuccg agcagaauuc cgggucuugc      540

gggugcccaa ccccagcucu aagcggaaug agcagaggau cgagcucuuc cagauccuuc      600

ggccagauga gcacauugcc aaacagcgcu auaucggugg caagaaucug cccacacggg      660

gcacugccga guggcugucc uuugauguca cugacacugu gcgugagugg cuguugagaa      720

gagaguccaa cuuaggucua gaaaucagca uucacugucc augucacacc uuucagccca      780

auggagauau ccuggaaaac auucacgagg ugauggaaau caaauucaaa ggcguggaca      840

augaggauga ccauggccgu ggagaucugg ggcgccucaa gaagcagaag gaucaccaca      900

acccucaucu aauccucaug augauucccc cacaccggcu cgacaacccg ggccaggggg      960

gucagaggaa gaagcgggcu uuggacacca auuacugcuu ccgcaacuug gaggagaacu     1020

gcugugugcg cccccucuac auugacuucc gacaggaucu gggcuggaag uggguccaug     1080

aaccuaaggg cuacuaugcc aacuucugcu caggcccuug cccauaccuc cgcagugcag     1140

acacaaccca cagcacggug cugggacugu acaacacucu gaacccugaa gcaucugccu     1200

cgccuugcug cgugccccag gaccuggagc cccugaccau ccuguacuau guugggagga     1260

cccccaaagu ggagcagcuc uccaacaugg uggugaaguc uuguaaaugu agcugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  3897
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (wt)

<400>  3897
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgcccgucg ccgucugggc cgcgcuggcc gucggacugg      120

agcucugggc ugcggcgcac gccuugcccg cccagguggc auuuacaccc uacgccccgg      180

agcccgggag cacaugccgg cucagagaau acuaugacca gacagcucag augugcugca      240

gcaaaugcuc gccgggccaa caugcaaaag ucuucuguac caagaccucg gacaccgugu      300

gugacuccug ugaggacagc acauacaccc agcucuggaa cuggguuccc gagugcuuga      360

gcuguggcuc ccgcuguagc ucugaccagg uggaaacuca agccugcacu cgggaacaga      420

accgcaucug caccugcagg cccggcuggu acugcgcgcu gagcaagcag gaggggugcc      480

ggcugugcgc gccgcugcgc aagugccgcc cgggcuucgg cguggccaga ccaggaacug      540

aaacaucaga cguggugugc aagcccugug ccccggggac guucuccaac acgacuucau      600

ccacggauau uugcaggccc caccagaucu guaacguggu ggccaucccu gggaaugcaa      660

gcauggaugc agucugcacg uccacguccc ccacccggag uauggcccca ggggcaguac      720

acuuacccca gccagugucc acacgauccc aacacacgca gccaacucca gaacccagca      780

cugcuccaag caccuccuuc cugcucccaa ugggccccag ccccccagcu gaagggagca      840

cuggcgacuu cgcucuucca guuggacuga uugugggugu gacagccuug ggucuacuaa      900

uaauaggagu ggugaacugu gucaucauga cccaggugaa aaagaagccc uugugccugc      960

agagagaagc caaggugccu cacuugccug ccgauaaggc ccgggguaca cagggccccg     1020

agcagcagca ccugcugauc acagcgccga gcuccagcag cagcucccug gagagcucgg     1080

ccagugcguu ggacagaagg gcgcccacuc ggaaccagcc acaggcacca ggcguggagg     1140

ccaguggggc cggggaggcc cgggccagca ccgggagcuc agauucuucc ccugguggcc     1200

augggaccca ggucaauguc accugcaucg ugaacgucug uagcagcucu gaccacagcu     1260

cacagugcuc cucccaagcc agcuccacaa ugggagacac agauuccagc cccucggagu     1320

ccccgaagga cgagcagguc cccuucucca aggaggaaug ugccuuucgg ucacagcugg     1380

agacgccaga gacccugcug gggagcaccg aagagaagcc ccugccccuu ggagugccug     1440

augcugggau gaagcccagu uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  3898
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (wt)

<400>  3898
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggucauga ggcuguuccc uugcuuccug cagcuccugg      120

ccgggcuggc gcugccugcu gugccccccc agcagugggc cuugucugcu gggaacggcu      180

cgucagaggu ggaaguggua cccuuccagg aagugugggg ccgcagcuac ugccgggcgc      240

uggagaggcu gguggacguc guguccgagu accccagcga gguggagcac auguucagcc      300

cauccugugu cucccugcug cgcugcaccg gcugcugcgg cgaugagaau cugcacugug      360

ugccggugga gacggccaau gucaccaugc agcuccuaaa gauccguucu ggggaccggc      420

ccuccuacgu ggagcugacg uucucucagc acguucgcug cgaaugccgg ccucugcggg      480

agaagaugaa gccggaaagg aggagaccca agggcagggg gaagaggagg agagagaagc      540

agagacccac agacugccac cugugcggcg augcuguucc ccggagguaa ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  3899
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (wt)

<400>  3899
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acggacagac agacagacac cgcccccagc cccagcuacc      120

accuccuccc cggccggcgg cggacagugg acgcggcggc gagccgcggg caggggccgg      180

agcccgcgcc cggaggcggg guggaggggg ucggggcucg cggcgucgca cugaaacuuu      240

ucguccaacu ucugggcugu ucucgcuucg gaggagccgu gguccgcgcg ggggaagccg      300

agccgagcgg agccgcgaga agugcuagcu cgggccggga ggagccgcag ccggaggagg      360

gggaggagga agaagagaag gaagaggaga gggggccgca guggcgacuc ggcgcucgga      420

agccgggcuc auggacgggu gaggcggcgg ugugcgcaga cagugcucca gccgcgcgcg      480

cuccccaggc ccuggcccgg gccucgggcc ggggaggaag aguagcucgc cgaggcgccg      540

aggagagcgg gccgccccac agcccgagcc ggagagggag cgcgagccgc gccggccccg      600

gucgggccuc cgaaaccaug aacuuucugc ugucuugggu gcauuggagc cuugccuugc      660

ugcucuaccu ccaccaugcc aagugguccc aggcugcacc cauggcagaa ggaggagggc      720

agaaucauca cgaaguggug aaguucaugg augucuauca gcgcagcuac ugccauccaa      780

ucgagacccu gguggacauc uuccaggagu acccugauga gaucgaguac aucuucaagc      840

cauccugugu gccccugaug cgaugcgggg gcugcugcaa ugacgagggc cuggagugug      900

ugcccacuga ggaguccaac aucaccaugc agauuaugcg gaucaaaccu caccaaggcc      960

agcacauagg agagaugagc uuccuacagc acaacaaaug ugaaugcaga ccaaagaaag     1020

auagagcaag acaagaaaaa aaaucaguuc gaggaaaggg aaaggggcaa aaacgaaagc     1080

gcaagaaauc ccgguauaag uccuggagcg uguacguugg ugcccgcugc ugucuaaugc     1140

ccuggagccu cccuggcccc caucccugug ggccuugcuc agagcggaga aagcauuugu     1200

uuguacaaga uccgcagacg uguaaauguu ccugcaaaaa cacagacucg cguugcaagg     1260

cgaggcagcu ugaguuaaac gaacguacuu gcagauguga caagccgagg cggugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  3900
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (wt)

<400>  3900
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuucugc ugucuugggu gcauuggagc cuugccuugc      120

ugcucuaccu ccaccaugcc aagugguccc aggcugcacc cauggcagaa ggaggagggc      180

agaaucauca cgaaguggug aaguucaugg augucuauca gcgcagcuac ugccauccaa      240

ucgagacccu gguggacauc uuccaggagu acccugauga gaucgaguac aucuucaagc      300

cauccugugu gccccugaug cgaugcgggg gcugcugcaa ugacgagggc cuggagugug      360

ugcccacuga ggaguccaac aucaccaugc agauuaugcg gaucaaaccu caccaaggcc      420

agcacauagg agagaugagc uuccuacagc acaacaaaug ugaaugcaga ccaaagaaag      480

auagagcaag acaagaaaaa aaaucaguuc gaggaaaggg aaaggggcaa aaacgaaagc      540

gcaagaaauc ccgguauaag uccuggagcg uguacguugg ugcccgcugc ugucuaaugc      600

ccuggagccu cccuggcccc caucccugug ggccuugcuc agagcggaga aagcauuugu      660

uuguacaaga uccgcagacg uguaaauguu ccugcaaaaa cacagacucg cguugcaagg      720

cgaggcagcu ugaguuaaac gaacguacuu gcagauguga caagccgagg cggugaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  3901
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (wt)

<400>  3901
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcccucugc uccgccgccu gcugcucgcc gcacuccugc      120

agcuggcccc cgcccaggcc ccugucuccc agccugaugc cccuggccac cagaggaaag      180

uggugucaug gauagaugug uauacucgcg cuaccugcca gccccgggag gugguggugc      240

ccuugacugu ggagcucaug ggcaccgugg ccaaacagcu ggugcccagc ugcgugacug      300

ugcagcgcug ugguggcugc ugcccugacg auggccugga gugugugccc acugggcagc      360

accaaguccg gaugcagauc cucaugaucc gguacccgag cagucagcug ggggagaugu      420

cccuggaaga acacagccag ugugaaugca gaccuaaaaa aaaggacagu gcugugaagc      480

cagacagggc ugccacuccc caccaccguc cccagccccg uucuguuccg ggcugggacu      540

cugcccccgg agcacccucc ccagcugaca ucacccaucc cacuccagcc ccaggccccu      600

cugcccacgc ugcacccagc accaccagcg cccugacccc cggaccugcc gcugccgcug      660

ccgacgccgc agcuuccucc guugccaagg gcggggcuua gggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  3902
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (wt)

<400>  3902
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuugcugg gcuucuucuc uguggcgugu ucucugcucg      120

ccgcugcgcu gcucccgggu ccucgcgagg cgcccgccgc cgccgccgcc uucgaguccg      180

gacucgaccu cucggacgcg gagcccgacg cgggcgaggc cacggcuuau gcaagcaaag      240

aucuggagga gcaguuacgg ucugugucca guguagauga acucaugacu guacucuacc      300

cagaauauug gaaaauguac aagugucagc uaaggaaagg aggcuggcaa cauaacagag      360

aacaggccaa ccucaacuca aggacagaag agacuauaaa auuugcugca gcacauuaua      420

auacagagau cuugaaaagu auugauaaug aguggagaaa gacucaaugc augccacggg      480

agguguguau agaugugggg aaggaguuug gagucgcgac aaacaccuuc uuuaaaccuc      540

cauguguguc cgucuacaga uguggggguu gcugcaauag ugaggggcug cagugcauga      600

acaccagcac gagcuaccuc agcaagacgu uauuugaaau uacagugccu cucucucaag      660

gccccaaacc aguaacaauc aguuuugcca aucacacuuc cugccgaugc augucuaaac      720

uggauguuua cagacaaguu cauuccauua uuagacguuc ccugccagca acacuaccac      780

agugucaggc agcgaacaag accugcccca ccaauuacau guggaauaau cacaucugca      840

gaugccuggc ucaggaagau uuuauguuuu ccucggaugc uggagaugac ucaacagaug      900

gauuccauga caucugugga ccaaacaagg agcuggauga agagaccugu cagugugucu      960

gcagagcggg gcuucggccu gccagcugug gaccccacaa agaacuagac agaaacucau     1020

gccagugugu cuguaaaaac aaacucuucc ccagccaaug uggggccaac cgagaauuug     1080

augaaaacac augccagugu guauguaaaa gaaccugccc cagaaaucaa ccccuaaauc     1140

cuggaaaaug ugccugugaa uguacagaaa guccacagaa augcuuguua aaaggaaaga     1200

aguuccacca ccaaacaugc agcuguuaca gacggccaug uacgaaccgc cagaaggcuu     1260

gugagccagg auuuucauau agugaagaag ugugucguug ugucccuuca uauuggaaaa     1320

gaccacaaau gagcuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  3903
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (wt)

<400>  3903
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagagu ggguaguggu gaauguuuuc augauguugu      120

acguccagcu ggugcagggc uccaguaaug aacauggacc agugaagcga ucaucucagu      180

ccacauugga acgaucugaa cagcagauca gggcugcuuc uaguuuggag gaacuacuuc      240

gaauuacuca cucugaggac uggaagcugu ggagaugcag gcugaggcuc aaaaguuuua      300

ccaguaugga cucucgcuca gcaucccauc gguccacuag guuugcggca acuuucuaug      360

acauugaaac acuaaaaguu auagaugaag aauggcaaag aacucagugc agcccuagag      420

aaacgugcgu ggagguggcc agugagcugg ggaagaguac caacacauuc uucaagcccc      480

cuugugugaa cguguuccga ugugguggcu guugcaauga agagagccuu aucuguauga      540

acaccagcac cucguacauu uccaaacagc ucuuugagau aucagugccu uugacaucag      600

uaccugaauu agugccuguu aaaguugcca aucauacagg uuguaagugc uugccaacag      660

ccccccgcca uccauacuca auuaucagaa gauccaucca gaucccugaa gaagaucgcu      720

guucccauuc caagaaacuc uguccuauug acaugcuaug ggauagcaac aaauguaaau      780

guguuuugca ggaggaaaau ccacuugcug gaacagaaga ccacucucau cuccaggaac      840

cagcucucug ugggccacac augauguuug acgaagaucg uugcgagugu gucuguaaaa      900

caccaugucc caaagaucua auccagcacc ccaaaaacug caguugcuuu gagugcaaag      960

aaagucugga gaccugcugc cagaagcaca agcuauuuca cccagacacc ugcagcugug     1020

aggacagaug ccccuuucau accagaccau gugcaagugg caaaacagca ugugcaaagc     1080

auugccgcuu uccaaaggag aaaagggcug cccaggggcc ccacagccga aagaauccuu     1140

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  3904
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt1)

<400>  3904
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgacg agaccggcuu cgagcacucc gggcuguggg      120

ugagcguccu cgccggccug cugcucgggg ccugccaggc ccaccccauc ccggacucca      180

gcccccugcu gcaguucggc ggccaggugc gccagcggua ccucuacacc gacgacgccc      240

agcagacgga ggcccaccug gagauccgcg aggacgggac cgugggcggg gccgccgacc      300

agucccccga gagccugcuc cagcugaagg cgcugaagcc cggcgucauc cagauccucg      360

gggugaagac cucccgguuc cugugccagc gcccggacgg cgcccuguac gggagccucc      420

acuucgaccc cgaggccugc uccuuccggg agcugcugcu cgaggacggc uacaacgugu      480

accagagcga ggcccacggc cugccccugc accuccccgg gaacaagucc ccgcaccgcg      540

accccgcgcc ccggggcccc gcccgcuucc ugccgcugcc cgggcucccg cccgcccugc      600

ccgagccgcc cggcauccug gcgccccagc cgcccgacgu cggcagcucc gacccccuca      660

gcaugguggg gcccucccag ggccggagcc ccuccuacgc cagcugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  3905
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt1)

<400>  3905
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuucc cgccccugcu ccugcugcuc uucuggggcg      120

uggucuccca cagcuucccc gccacccugg agacccagga gcaggacgug gaccuggugc      180

agaaguaccu cgagaaguac uacaaccuga agaacgacgg gcgccagguc gagaagcggc      240

gcaacuccgg ccccguggug gagaagcuga agcagaugca ggaguucuuc gggcucaagg      300

ucacgggcaa gcccgacgcc gagacccuga aggugaugaa gcagccgcgg ugcggggugc      360

ccgacgucgc gcaguucgug cugaccgagg gcaacccccg cugggagcag acccaccuca      420

cguaccggau cgagaacuac acccccgacc ugccgcgcgc cgacguggac cacgccaucg      480

agaaggccuu ccagcugugg agcaacguca ccccgcucac cuucacgaag guguccgagg      540

gccaggccga caucaugauc agcuucgugc ggggcgacca ccgcgacaac ucccccuucg      600

acgggcccgg gggcaaccug gcgcacgccu uccagccggg gcccggcauc ggcggggacg      660

cccacuucga cgaggacgag cgguggacca acaacuuccg cgaguacaac cugcaccggg      720

ucgccgcgca cgagcucggc cacagccugg ggcuguccca cagcaccgac aucggcgccc      780

ucauguaccc cuccuacacc uucagcggcg acgugcagcu ggcccaggac gacaucgacg      840

ggauccaggc caucuacggc cgcucccaga accccgugca gccgaucggg ccccagacgc      900

ccaaggccug cgacagcaag cugaccuucg acgcgaucac caccauccgg ggcgagguca      960

uguucuucaa ggaccgcuuc uacaugcgga cgaaccccuu cuacccggag guggagcuca     1020

acuucaucuc cguguucugg ccccagcugc ccaacgggcu ggaggccgcc uacgaguucg     1080

ccgaccgcga cgagguccgg uucuucaagg gcaacaagua cugggccgug cagggccaga     1140

acgugcucca cggguacccc aaggacaucu acagcuccuu cggcuucccg cgcaccguca     1200

agcacaucga cgcggcccug agcgaggaga acaccgggaa gaccuacuuc uucguggcca     1260

acaaguacug gcgguacgac gaguacaagc gcuccaugga ccccggcuac cccaagauga     1320

ucgcccacga cuuccccggg aucggccaca aggucgacgc cguguucaug aaggacggcu     1380

ucuucuacuu cuuccacggg acgcggcagu acaaguucga cccgaagacc aagcgcaucc     1440

ugacccucca gaaggcgaac agcugguuca acugccgcaa gaacugagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  3906
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt1)

<400>  3906
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuucc cgccccugcu ccugcugcuc uucuggggcg      120

uggucuccca cagcuucgug cugaccgagg gcaacccccg cugggagcag acccaccuca      180

cguaccggau cgagaacuac acccccgacc ugccgcgcgc cgacguggac cacgccaucg      240

agaaggccuu ccagcugugg agcaacguca ccccgcucac cuucacgaag guguccgagg      300

gccaggccga caucaugauc agcuucgugc ggggcgacca ccgcgacaac ucccccuucg      360

acgggcccgg gggcaaccug gcgcacgccu uccagccggg gcccggcauc ggcggggacg      420

cccacuucga cgaggacgag cgguggacca acaacuuccg cgaguacaac cugcaccggg      480

ucgccgcgca cgagcucggc cacagccugg ggcuguccca cagcaccgac aucggcgccc      540

ucauguaccc cuccuacacc uucagcggcg acgugcagcu ggcccaggac gacaucgacg      600

ggauccaggc caucuacggc cgcucccaga accccgugca gccgaucggg ccccagacgc      660

ccaaggccug cgacagcaag cugaccuucg acgcgaucac caccauccgg ggcgagguca      720

uguucuucaa ggaccgcuuc uacaugcgga cgaaccccuu cuacccggag guggagcuca      780

acuucaucuc cguguucugg ccccagcugc ccaacgggcu ggaggccgcc uacgaguucg      840

ccgaccgcga cgagguccgg uucuucaagg gcaacaagua cugggccgug cagggccaga      900

acgugcucca cggguacccc aaggacaucu acagcuccuu cggcuucccg cgcaccguca      960

agcacaucga cgcggcccug agcgaggaga acaccgggaa gaccuacuuc uucguggcca     1020

acaaguacug gcgguacgac gaguacaagc gcuccaugga ccccggcuac cccaagauga     1080

ucgcccacga cuuccccggg aucggccaca aggucgacgc cguguucaug aaggacggcu     1140

ucuucuacuu cuuccacggg acgcggcagu acaaguucga cccgaagacc aagcgcaucc     1200

ugacccucca gaaggcgaac agcugguuca acugccgcaa gaacugagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  3907
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt1)

<400>  3907
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaagaaca uccugaagau ccucauggac agcuacucca      120

aggagagcaa gauccagacc gugcgccggg ucaccuccgu gagccugcug gccguguacc      180

ucacgaugaa caccuccagc cugguccugg ccaagcccau cgagaacacc aacgacaccu      240

ccaucaagaa cguggagaag cuccgcaacg cgcccaacga ggagaacagc aagaaggugg      300

aggacuccaa gaacgacaag gucgagcacg ugaagaacau cgaggaggcc aagguggagc      360

aggucgcccc cgaggugaag agcaagucca cgcugcggag cgccuccauc gccaacacca      420

acagcgagaa guacgacuuc gaguaccuga acggccucuc cuacaccgag cugaccaacc      480

ugaucaagaa caucaagugg aaccagauca acgggcucuu caacuacagc acgggcuccc      540

agaaguucuu cggggacaag aaccgcgugc aggcgaucau caacgcccug caggagagcg      600

gccggaccua caccgccaac gacaugaagg ggaucgagac cuucacggag guccugcgcg      660

ccggcuucua ccucggcuac uacaacgacg ggcuguccua ccugaacgac cggaacuucc      720

aggacaagug cauccccgcg augaucgcca uccagaagaa ccccaacuuc aagcucggca      780

ccgccgugca ggacgaggug aucaccagcc uggggaagcu gaucggcaac gccagcgcca      840

acgcggaggu cgugaacaac ugcgugccgg uccucaagca guuccgcgag aaccugaacc      900

aguacgcccc cgacuacgug aaggggaccg ccgugaacga gcugaucaag ggcaucgagu      960

ucgacuucuc cggcgccgcc uacgagaagg acgucaagac gaugcccugg uacgggaaga     1020

ucgaccccuu caucaacgag cucaaggcgc ugggccugua cgggaacauc accagcgcca     1080

ccgagugggc cuccgacgug ggcaucuacu accucagcaa guucggccug uacuccacca     1140

accggaacga caucgugcag agccuggaga aggccgucga cauguacaag uacgggaaga     1200

ucgccuucgu ggcgauggag cgcaucacgu gggacuacga cggcaucggg uccaacggca     1260

agaaggucga ccacgacaag uuccucgacg acgccgagaa gcacuaccug ccgaagaccu     1320

acaccuucga caacgggacc uucaucaucc gggccggcga caaggugagc gaggagaaga     1380

ucaagcgccu guacugggcc ucccgggagg ugaagagcca guuccaccgc gucgugggca     1440

acgacaaggc ccucgaggug gggaacgcgg acgacguccu gacgaugaag aucuucaacu     1500

cccccgagga guacaaguuc aacaccaaca ucaacggcgu gagcaccgac aacgggggcc     1560

uguacaucga gccgcggggg accuucuaca cguacgagcg caccccgcag caguccaucu     1620

ucagccucga ggagcuguuc cggcacgagu acacccacua ccugcaggcc cgcuaccucg     1680

uggacggccu guggggccag gggccguucu acgagaagaa ccggcugacc ugguucgacg     1740

agggcacggc cgaguucuuc gccgggucca cccgcaccag cggcguccuc ccccggaagu     1800

ccauccuggg guaccuggcg aaggacaagg uggaccaccg cuacagccuc aagaagaccc     1860

ugaacuccgg cuacgacgac agcgacugga uguucuacaa cuacggcuuc gccguggccc     1920

acuaccugua cgagaaggac augcccacgu ucaucaagau gaacaaggcc auccugaaca     1980

ccgacgucaa gagcuacgac gagaucauca agaagcucuc cgacgacgcc aacaagaaca     2040

ccgaguacca gaaccacauc caggagcugg cggacaagua ccagggggcc ggcauccccc     2100

uggugagcga cgacuaccuc aaggaccacg gguacaagaa ggccuccgag guguacagcg     2160

agaucuccaa ggccgccagc cugaccaaca ccuccgucac ggcggagaag agccaguacu     2220

ucaacaccuu cacccugcgc ggcaccuaca cgggcgagac cuccaagggg gaguucaagg     2280

acugggacga gaugagcaag aagcucgacg gcacccugga gucccuggcc aagaacagcu     2340

gguccgggua caagacccuc acggccuacu ucaccaacua ccgggugacc agcgacaaca     2400

aggugcagua cgacgucgug uuccacggcg ugcugaccga caacgccgac aucuccaaca     2460

acaaggcccc gaucgcgaag gucacggggc ccagcaccgg cgccgugggc cgcaacaucg     2520

aguucuccgg gaaggacagc aaggacgagg acggcaagau cgugagcuac gacugggacu     2580

ucggggacgg cgccaccucc cgggggaaga acagcgucca cgccuacaag aaggcgggca     2640

ccuacaacgu gacgcugaag gugaccgacg acaagggcgc caccgccacc gaguccuuca     2700

cgaucgagau caagaacgag gacaccacca cccccaucac gaaggagaug gagcccaacg     2760

acgacaucaa ggaggccaac gggccgaucg ucgagggcgu gaccgugaag ggggaccuca     2820

acggcagcga cgacgccgac accuucuacu ucgacgucaa ggaggacggg gacgugacca     2880

ucgagcugcc cuacuccggc agcuccaacu ucacguggcu gguguacaag gagggcgacg     2940

accagaacca caucgcgagc gggaucgaca agaacaacuc caaggucggc accuucaaga     3000

gcaccaaggg gcgccacuac guguucaucu acaagcacga cuccgccagc aacaucuccu     3060

acagccucaa caucaagggc cuggggaacg agaagcugaa ggagaaggag aacaacgacu     3120

ccagcgacaa ggccaccgug auccccaacu ucaacacgac caugcagggc ucccuccugg     3180

gcgacgacag ccgggacuac uacuccuucg aggucaagga ggagggggag gugaacaucg     3240

agcuggacaa gaaggacgag uucggcguga ccuggacccu ccaccccgag agcaacauca     3300

acgaccgcau cacguacggg caggucgacg gcaacaaggu gagcaacaag gugaagcugc     3360

ggccgggcaa guacuaccug cucgucuaca aguacuccgg gagcggcaac uacgagcugc     3420

gcgugaacaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  3908
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt1)

<400>  3908
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuc cuguucucca      120

gcgccuacuc caucgccaac accaacagcg agaaguacga cuucgaguac cugaacggcc      180

ucuccuacac cgagcugacc aaccugauca agaacaucaa guggaaccag aucaacgggc      240

ucuucaacua cagcacgggc ucccagaagu ucuucgggga caagaaccgc gugcaggcga      300

ucaucaacgc ccugcaggag agcggccgga ccuacaccgc caacgacaug aaggggaucg      360

agaccuucac ggagguccug cgcgccggcu ucuaccucgg cuacuacaac gacgggcugu      420

ccuaccugaa cgaccggaac uuccaggaca agugcauccc cgcgaugauc gccauccaga      480

agaaccccaa cuucaagcuc ggcaccgccg ugcaggacga ggugaucacc agccugggga      540

agcugaucgg caacgccagc gccaacgcgg aggucgugaa caacugcgug ccgguccuca      600

agcaguuccg cgagaaccug aaccaguacg cccccgacua cgugaagggg accgccguga      660

acgagcugau caagggcauc gaguucgacu ucuccggcgc cgccuacgag aaggacguca      720

agacgaugcc cugguacggg aagaucgacc ccuucaucaa cgagcucaag gcgcugggcc      780

uguacgggaa caucaccagc gccaccgagu gggccuccga cgugggcauc uacuaccuca      840

gcaaguucgg ccuguacucc accaaccgga acgacaucgu gcagagccug gagaaggccg      900

ucgacaugua caaguacggg aagaucgccu ucguggcgau ggagcgcauc acgugggacu      960

acgacggcau cggguccaac ggcaagaagg ucgaccacga caaguuccuc gacgacgccg     1020

agaagcacua ccugccgaag accuacaccu ucgacaacgg gaccuucauc auccgggccg     1080

gcgacaaggu gagcgaggag aagaucaagc gccuguacug ggccucccgg gaggugaaga     1140

gccaguucca ccgcgucgug ggcaacgaca aggcccucga gguggggaac gcggacgacg     1200

uccugacgau gaagaucuuc aacucccccg aggaguacaa guucaacacc aacaucaacg     1260

gcgugagcac cgacaacggg ggccuguaca ucgagccgcg ggggaccuuc uacacguacg     1320

agcgcacccc gcagcagucc aucuucagcc ucgaggagcu guuccggcac gaguacaccc     1380

acuaccugca ggcccgcuac cucguggacg gccugugggg ccaggggccg uucuacgaga     1440

agaaccggcu gaccugguuc gacgagggca cggccgaguu cuucgccggg uccacccgca     1500

ccagcggcgu ccucccccgg aaguccaucc ugggguaccu ggcgaaggac aagguggacc     1560

accgcuacag ccucaagaag acccugaacu ccggcuacga cgacagcgac uggauguucu     1620

acaacuacgg cuucgccgug gcccacuacc uguacgagaa ggacaugccc acguucauca     1680

agaugaacaa ggccauccug aacaccgacg ucaagagcua cgacgagauc aucaagaagc     1740

ucuccgacga cgccaacaag aacaccgagu accagaacca cauccaggag cuggcggaca     1800

aguaccaggg ggccggcauc ccccugguga gcgacgacua ccucaaggac cacggguaca     1860

agaaggccuc cgagguguac agcgagaucu ccaaggccgc cagccugacc aacaccuccg     1920

ucacggcgga gaagagccag uacuucaaca ccuucacccu gcgcggcacc uacacgggcg     1980

agaccuccaa gggggaguuc aaggacuggg acgagaugag caagaagcuc gacggcaccc     2040

uggagucccu ggccaagaac agcugguccg gguacaagac ccucacggcc uacuucacca     2100

acuaccgggu gaccagcgac aacaaggugc aguacgacgu cguguuccac ggcgugcuga     2160

ccgacaacgc cgacaucucc aacaacaagg ccccgaucgc gaaggucacg gggcccagca     2220

ccggcgccgu gggccgcaac aucgaguucu ccgggaagga cagcaaggac gaggacggca     2280

agaucgugag cuacgacugg gacuucgggg acggcgccac cucccggggg aagaacagcg     2340

uccacgccua caagaaggcg ggcaccuaca acgugacgcu gaaggugacc gacgacaagg     2400

gcgccaccgc caccgagucc uucacgaucg agaucaagaa cgaggacacc accaccccca     2460

ucacgaagga gauggagccc aacgacgaca ucaaggaggc caacgggccg aucgucgagg     2520

gcgugaccgu gaagggggac cucaacggca gcgacgacgc cgacaccuuc uacuucgacg     2580

ucaaggagga cggggacgug accaucgagc ugcccuacuc cggcagcucc aacuucacgu     2640

ggcuggugua caaggagggc gacgaccaga accacaucgc gagcgggauc gacaagaaca     2700

acuccaaggu cggcaccuuc aagagcacca aggggcgcca cuacguguuc aucuacaagc     2760

acgacuccgc cagcaacauc uccuacagcc ucaacaucaa gggccugggg aacgagaagc     2820

ugaaggagaa ggagaacaac gacuccagcg acaaggccac cgugaucccc aacuucaaca     2880

cgaccaugca gggcucccuc cugggcgacg acagccggga cuacuacucc uucgagguca     2940

aggaggaggg ggaggugaac aucgagcugg acaagaagga cgaguucggc gugaccugga     3000

cccuccaccc cgagagcaac aucaacgacc gcaucacgua cgggcagguc gacggcaaca     3060

aggugagcaa caaggugaag cugcggccgg gcaaguacua ccugcucguc uacaaguacu     3120

ccgggagcgg caacuacgag cugcgcguga acaagugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  3909
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt1)

<400>  3909
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuc cuguucucca      120

gcgccuacuc caugaagaag aacauccuga agauccucau ggacagcuac uccaaggaga      180

gcaagaucca gaccgugcgc cgggucaccu ccgugagccu gcuggccgug uaccucacga      240

ugaacaccuc cagccugguc cuggccaagc ccaucgagaa caccaacgac accuccauca      300

agaacgugga gaagcuccgc aacgcgccca acgaggagaa cagcaagaag guggaggacu      360

ccaagaacga caaggucgag cacgugaaga acaucgagga ggccaaggug gagcaggucg      420

cccccgaggu gaagagcaag uccacgcugc ggagcgccuc ccgccggcgc cggaagcgca      480

ucgccaacac caacagcgag aaguacgacu ucgaguaccu gaacggccuc uccuacaccg      540

agcugaccaa ccugaucaag aacaucaagu ggaaccagau caacgggcuc uucaacuaca      600

gcacgggcuc ccagaaguuc uucggggaca agaaccgcgu gcaggcgauc aucaacgccc      660

ugcaggagag cggccggacc uacaccgcca acgacaugaa ggggaucgag accuucacgg      720

agguccugcg cgccggcuuc uaccucggcu acuacaacga cgggcugucc uaccugaacg      780

accggaacuu ccaggacaag ugcauccccg cgaugaucgc cauccagaag aaccccaacu      840

ucaagcucgg caccgccgug caggacgagg ugaucaccag ccuggggaag cugaucggca      900

acgccagcgc caacgcggag gucgugaaca acugcgugcc gguccucaag caguuccgcg      960

agaaccugaa ccaguacgcc cccgacuacg ugaaggggac cgccgugaac gagcugauca     1020

agggcaucga guucgacuuc uccggcgccg ccuacgagaa ggacgucaag acgaugcccu     1080

gguacgggaa gaucgacccc uucaucaacg agcucaaggc gcugggccug uacgggaaca     1140

ucaccagcgc caccgagugg gccuccgacg ugggcaucua cuaccucagc aaguucggcc     1200

uguacuccac caaccggaac gacaucgugc agagccugga gaaggccguc gacauguaca     1260

aguacgggaa gaucgccuuc guggcgaugg agcgcaucac gugggacuac gacggcaucg     1320

gguccaacgg caagaagguc gaccacgaca aguuccucga cgacgccgag aagcacuacc     1380

ugccgaagac cuacaccuuc gacaacggga ccuucaucau ccgggccggc gacaagguga     1440

gcgaggagaa gaucaagcgc cuguacuggg ccucccggga ggugaagagc caguuccacc     1500

gcgucguggg caacgacaag gcccucgagg uggggaacgc ggacgacguc cugacgauga     1560

agaucuucaa cucccccgag gaguacaagu ucaacaccaa caucaacggc gugagcaccg     1620

acaacggggg ccuguacauc gagccgcggg ggaccuucua cacguacgag cgcaccccgc     1680

agcaguccau cuucagccuc gaggagcugu uccggcacga guacacccac uaccugcagg     1740

cccgcuaccu cguggacggc cuguggggcc aggggccguu cuacgagaag aaccggcuga     1800

ccugguucga cgagggcacg gccgaguucu ucgccggguc cacccgcacc agcggcgucc     1860

ucccccggaa guccauccug ggguaccugg cgaaggacaa gguggaccac cgcuacagcc     1920

ucaagaagac ccugaacucc ggcuacgacg acagcgacug gauguucuac aacuacggcu     1980

ucgccguggc ccacuaccug uacgagaagg acaugcccac guucaucaag augaacaagg     2040

ccauccugaa caccgacguc aagagcuacg acgagaucau caagaagcuc uccgacgacg     2100

ccaacaagaa caccgaguac cagaaccaca uccaggagcu ggcggacaag uaccaggggg     2160

ccggcauccc ccuggugagc gacgacuacc ucaaggacca cggguacaag aaggccuccg     2220

agguguacag cgagaucucc aaggccgcca gccugaccaa caccuccguc acggcggaga     2280

agagccagua cuucaacacc uucacccugc gcggcaccua cacgggcgag accuccaagg     2340

gggaguucaa ggacugggac gagaugagca agaagcucga cggcacccug gagucccugg     2400

ccaagaacag cugguccggg uacaagaccc ucacggccua cuucaccaac uaccggguga     2460

ccagcgacaa caaggugcag uacgacgucg uguuccacgg cgugcugacc gacaacgccg     2520

acaucuccaa caacaaggcc ccgaucgcga aggucacggg gcccagcacc ggcgccgugg     2580

gccgcaacau cgaguucucc gggaaggaca gcaaggacga ggacggcaag aucgugagcu     2640

acgacuggga cuucggggac ggcgccaccu cccgggggaa gaacagcguc cacgccuaca     2700

agaaggcggg caccuacaac gugacgcuga aggugaccga cgacaagggc gccaccgcca     2760

ccgaguccuu cacgaucgag aucaagaacg aggacaccac cacccccauc acgaaggaga     2820

uggagcccaa cgacgacauc aaggaggcca acgggccgau cgucgagggc gugaccguga     2880

agggggaccu caacggcagc gacgacgccg acaccuucua cuucgacguc aaggaggacg     2940

gggacgugac caucgagcug cccuacuccg gcagcuccaa cuucacgugg cugguguaca     3000

aggagggcga cgaccagaac cacaucgcga gcgggaucga caagaacaac uccaaggucg     3060

gcaccuucaa gagcaccaag gggcgccacu acguguucau cuacaagcac gacuccgcca     3120

gcaacaucuc cuacagccuc aacaucaagg gccuggggaa cgagaagcug aaggagaagg     3180

agaacaacga cuccagcgac aaggccaccg ugauccccaa cuucaacacg accaugcagg     3240

gcucccuccu gggcgacgac agccgggacu acuacuccuu cgaggucaag gaggaggggg     3300

aggugaacau cgagcuggac aagaaggacg aguucggcgu gaccuggacc cuccaccccg     3360

agagcaacau caacgaccgc aucacguacg ggcaggucga cggcaacaag gugagcaaca     3420

aggugaagcu gcggccgggc aaguacuacc ugcucgucua caaguacucc gggagcggca     3480

acuacgagcu gcgcgugaac aagugaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  3910
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt1)

<400>  3910
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuga agaucauccu caaccgcggc aagaccauga      120

agcggaagug ccugagcaag cgccugaugc ucgccaucac cauggccacg aucuucaccg      180

ugaacuccac ccugcccauc uacgcggccg ucgacaagaa caacgccacc gccgccgugc      240

agaacgagag caagcgguac acgguguccu accugaagac ccucaacuac uacgaccugg      300

ucgaccugcu cgugaagacc gagaucgaga accugccgga ccuguuccag uacagcuccg      360

acgcgaagga guucuacggg aacaagaccc gcaugagcuu caucauggac gagaucggcc      420

ggcgcgcgcc ccaguacacg gagaucgacc acaaggggau ccccacccuc guggaggucg      480

ugcgggccgg cuucuaccug ggguuccaca acaaggagcu gaacgagauc aacaagcgcu      540

ccuucaagga gcgggugauc cccagcaucc ucgccaucca gaagaacccg aacuucaagc      600

ugggcaccga gguccaggac aagaucgugu ccgccaccgg ccugcucgcc gggaacgaga      660

cggccccgcc cgaggugguc aacaacuuca cccccauccu gcaggacugc aucaagaaca      720

ucgaccgcua cgcccuggac gaccucaaga gcaaggcccu guucaacgug cuggcggccc      780

cgaccuacga caucaccgag uaccuccggg ccacgaagga gaagcccgag aacacccccu      840

gguacggcaa gaucgacggg uucaucaacg agcugaagaa gcuggcccuc uacggcaaga      900

ucaacgacaa caacuccugg aucaucgaca acgggaucua ccacaucgcg ccccugggca      960

agcugcacag caacaacaag aucggcaucg agacccucac cgaggugaug aaggucuacc     1020

cguaccuguc caugcagcac cuccagagcg ccgaccagau caagcgccac uacgacucca     1080

aggacgccga ggggaacaag aucccccugg acaaguucaa gaaggagggc aaggagaagu     1140

acugccccaa gacguacacc uucgacgacg ggaaggugau caucaaggcc ggcgcccggg     1200

uggaggagga gaaggucaag cgccuguacu gggccagcaa ggaggugaac ucccaguucu     1260

uccgggugua cggcaucgac aagccccugg aggaggggaa cccggacgac auccucacca     1320

uggucaucua caacagcccc gaggaguaca agcugaacuc cgugcuguac ggcuacgaca     1380

ccaacaacgg gggcauguac aucgagcccg aggggacguu cuucaccuac gagcgcgagg     1440

cgcaggagag caccuacacc cucgaggagc uguuccggca cgaguacacg cacuaccugc     1500

agggccgcua cgccgugccc ggccaguggg ggcggaccaa gcucuacgac aacgaccgcc     1560

ugaccuggua cgaggagggc ggggccgagc uguucgccgg cagcacccgg acguccggga     1620

uccucccgcg caagagcauc gucuccaaca uccacaacac cacccgcaac aaccgguaca     1680

agcugagcga caccgugcac uccaaguacg gcgccagcuu cgaguucuac aacuacgcgu     1740

gcauguucau ggacuacaug uacaacaagg acaugggcau ccugaacaag cucaacgacc     1800

uggccaagaa caacgacguc gacggguacg acaacuacau ccgcgaccug uccagcaacu     1860

acgcccugaa cgacaaguac caggaccaca ugcaggagcg gaucgacaac uacgagaacc     1920

ucacggugcc cuucguggcc gacgacuacc ugguccgcca cgcguacaag aaccccaacg     1980

agaucuacuc cgagaucagc gagguggcca agcugaagga cgccaagucc gaggugaaga     2040

agucccagua cuucagcacc uucacccucc ggggcagcua caccgggggc gccuccaagg     2100

ggaagcugga ggaccagaag gccaugaaca aguucaucga cgacagccug aagaagcucg     2160

acaccuacuc cuggagcggc uacaagacgc ugaccgcgua cuucaccaac uacaaggucg     2220

acuccagcaa ccgcgugacc uacgacgugg ucuuccacgg cuaccugccc aacgaggggg     2280

acagcaagaa cucccucccg uacggcaaga ucaacgggac guacaagggc accgagaagg     2340

agaagaucaa guucagcucc gagggcagcu ucgaccccga cgggaagauc guguccuacg     2400

agugggacuu cggcgacggg aacaagagca acgaggagaa ccccgagcac uccuacgaca     2460

aggugggcac cuacaccguc aagcugaagg ugacggacga caagggggag agcuccguga     2520

gcaccaccac cgccgagauc aaggaccugu ccgagaacaa gcuccccguc aucuacaugc     2580

acgugcccaa gagcggcgcc cugaaccaga agguggucuu cuacggcaag gggacguacg     2640

accccgacgg cuccaucgcc ggguaccagu gggacuucgg cgacgggagc gacuucucca     2700

gcgagcagaa ccccucccac guguacacca agaagggcga guacaccgug acccugcggg     2760

ucauggacag cagcggccag auguccgaga agacgaugaa gaucaagauc accgacccgg     2820

uguaccccau cgggaccgag aaggagccca acaacagcaa ggagaccgcc uccggcccca     2880

ucgugccggg gauccccguc agcggcacga ucgagaacac cuccgaccag gacuacuucu     2940

acuucgacgu gaucaccccc ggggagguga agaucgacau caacaagcuc ggcuacggcg     3000

gggcgaccug ggucguguac gacgagaaca acaacgccgu gagcuacgcc acggacgacg     3060

gccagaaccu guccgggaag uucaaggccg acaagcccgg ccgcuacuac auccaccugu     3120

acauguucaa cgggagcuac augccguacc ggaucaacau cgagggcucc gucggccgcu     3180

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  3911
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt1)

<400>  3911
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcgcaagu gccugagcaa gcggcucaug cuggccauca      120

ccauggccac caucuucacg gugaacucca cccugcccau cuacgcggcc gucgacaaga      180

acaacgccac cgccgccgug cagaacgaga gcaagcgcua caccgugucc uaccucaaga      240

cgcugaacua cuacgaccug gucgaccucc uggugaagac cgagaucgag aaccugcccg      300

accucuucca guacagcucc gacgcgaagg aguucuacgg caacaagacc cggaugagcu      360

ucaucaugga cgagaucggg cgccgggccc cgcaguacac cgagaucgac cacaagggca      420

uccccacgcu gguggagguc gugcgcgccg gguucuaccu gggcuuccac aacaaggagc      480

ucaacgagau caacaagcgg uccuucaagg agcgcgugau ccccagcauc cuggccaucc      540

agaagaaccc gaacuucaag cuggggaccg agguccagga caagaucgug uccgcgaccg      600

gccuccuggc cggcaacgag accgccccgc ccgagguggu caacaacuuc acgcccaucc      660

ugcaggacug caucaagaac aucgaccggu acgcccucga cgaccugaag agcaaggccc      720

uguucaacgu gcucgcggcc ccgaccuacg acaucaccga guaccugcgc gccaccaagg      780

agaagcccga gaacacgccg ugguacggga agaucgacgg cuucaucaac gagcugaaga      840

agcucgcccu guacgggaag aucaacgaca acaacuccug gaucaucgac aacggcaucu      900

accacaucgc cccccugggg aagcuccaca gcaacaacaa gaucggcauc gagacccuga      960

ccgaggugau gaaggucuac ccguaccugu ccaugcagca ccuccagagc gcggaccaga     1020

ucaagcggca cuacgacucc aaggacgccg agggcaacaa gaucccccug gacaaguuca     1080

agaaggaggg gaaggagaag uacugcccca agaccuacac guucgacgac ggcaagguga     1140

ucaucaaggc cggggcccgc guggaggagg agaaggucaa gcggcuguac ugggccagca     1200

aggaggugaa cucccaguuc uuccgcgugu acggcaucga caagccccuc gaggagggca     1260

acccggacga cauccugacc auggucaucu acaacagccc cgaggaguac aagcugaacu     1320

ccgugcucua cggguacgac accaacaacg gcgggaugua caucgagccc gagggcaccu     1380

ucuucacgua cgagcgggag gcgcaggaga gcaccuacac ccuggaggag cuguuccgcc     1440

acgaguacac ccacuaccuc caggggcggu acgccgugcc cggccagugg ggccgcacga     1500

agcuguacga caacgaccgg cugaccuggu acgaggaggg cggcgccgag cucuucgccg     1560

ggagcacccg caccuccggg auccugccgc ggaagagcau cgucuccaac auccacaaca     1620

cgacccgcaa caaccgcuac aagcugagcg acaccgugca cuccaaguac ggggccagcu     1680

ucgaguucua caacuacgcg ugcauguuca uggacuacau guacaacaag gacaugggca     1740

uccucaacaa gcugaacgac cuggccaaga acaacgacgu cgacggcuac gacaacuaca     1800

uccgggaccu guccagcaac uacgcccuca acgacaagua ccaggaccac augcaggagc     1860

gcaucgacaa cuacgagaac cugaccgugc ccuucguggc cgacgacuac cugguccggc     1920

acgcguacaa gaaccccaac gagaucuacu ccgagaucag cgagguggcc aagcucaagg     1980

acgccaaguc cgaggugaag aagagccagu acuucuccac guucacccug cgcgggagcu     2040

acaccggcgg ggccuccaag ggcaagcugg aggaccagaa ggccaugaac aaguucaucg     2100

acgacagccu caagaagcug gacaccuacu ccuggagcgg guacaagacc cugacggcgu     2160

acuucaccaa cuacaagguc gacuccagca accgggugac cuacgacgug gucuuccacg     2220

gcuaccuccc caacgagggc gacagcaaga acucccugcc guacgggaag aucaacggca     2280

ccuacaaggg gacggagaag gagaagauca aguucagcuc cgagggcagc uucgaccccg     2340

acggcaagau cguguccuac gagugggacu ucggggacgg caacaagagc aacgaggaga     2400

accccgagca cuccuacgac aaggugggga ccuacaccgu caagcugaag gugaccgacg     2460

acaagggcga gagcuccgug agcacgacca ccgccgagau caaggaccuc uccgagaaca     2520

agcugcccgu caucuacaug cacgugccga agagcggggc ccugaaccag aagguggucu     2580

ucuacggcaa gggcaccuac gaccccgacg gguccaucgc cggcuaccag ugggacuucg     2640

gggacggcag cgacuucucc agcgagcaga accccuccca cguguacacg aagaaggggg     2700

aguacaccgu gacccuccgc gucauggaca gcagcggcca gauguccgag aagaccauga     2760

agaucaagau cacggacccg guguacccca ucggcaccga gaaggagccc aacaacagca     2820

aggagaccgc cuccgggccc aucgugccgg gcauccccgu cagcgggacc aucgagaaca     2880

cguccgacca ggacuacuuc uacuucgacg ugaucacccc cggcgaggug aagaucgaca     2940

ucaacaagcu gggguacggc ggcgcgaccu gggucgugua cgacgagaac aacaacgccg     3000

ugagcuacgc caccgacgac gggcagaacc uguccggcaa guucaaggcc gacaagcccg     3060

ggcgguacua cauccaccuc uacauguuca acggcagcua caugccguac cgcaucaaca     3120

ucgagggguc cgucggccgg ugaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  3912
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt1)

<400>  3912
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuc cuguucucca      120

gcgccuacuc cgugcagaac gagagcaagc gcuacaccgu guccuaccuc aagacgcuga      180

acuacuacga ccuggucgac cuccugguga agaccgagau cgagaaccug cccgaccucu      240

uccaguacag cuccgacgcg aaggaguucu acggcaacaa gacccggaug agcuucauca      300

uggacgagau cgggcgccgg gccccgcagu acaccgagau cgaccacaag ggcaucccca      360

cgcuggugga ggucgugcgc gccggguucu accugggcuu ccacaacaag gagcucaacg      420

agaucaacaa gcgguccuuc aaggagcgcg ugauccccag cauccuggcc auccagaaga      480

acccgaacuu caagcugggg accgaggucc aggacaagau cguguccgcg accggccucc      540

uggccggcaa cgagaccgcc ccgcccgagg uggucaacaa cuucacgccc auccugcagg      600

acugcaucaa gaacaucgac cgguacgccc ucgacgaccu gaagagcaag gcccuguuca      660

acgugcucgc ggccccgacc uacgacauca ccgaguaccu gcgcgccacc aaggagaagc      720

ccgagaacac gccgugguac gggaagaucg acggcuucau caacgagcug aagaagcucg      780

cccuguacgg gaagaucaac gacaacaacu ccuggaucau cgacaacggc aucuaccaca      840

ucgccccccu ggggaagcuc cacagcaaca acaagaucgg caucgagacc cugaccgagg      900

ugaugaaggu cuacccguac cuguccaugc agcaccucca gagcgcggac cagaucaagc      960

ggcacuacga cuccaaggac gccgagggca acaagauccc ccuggacaag uucaagaagg     1020

aggggaagga gaaguacugc cccaagaccu acacguucga cgacggcaag gugaucauca     1080

aggccggggc ccgcguggag gaggagaagg ucaagcggcu guacugggcc agcaaggagg     1140

ugaacuccca guucuuccgc guguacggca ucgacaagcc ccucgaggag ggcaacccgg     1200

acgacauccu gaccaugguc aucuacaaca gccccgagga guacaagcug aacuccgugc     1260

ucuacgggua cgacaccaac aacggcggga uguacaucga gcccgagggc accuucuuca     1320

cguacgagcg ggaggcgcag gagagcaccu acacccugga ggagcuguuc cgccacgagu     1380

acacccacua ccuccagggg cgguacgccg ugcccggcca guggggccgc acgaagcugu     1440

acgacaacga ccggcugacc ugguacgagg agggcggcgc cgagcucuuc gccgggagca     1500

cccgcaccuc cgggauccug ccgcggaaga gcaucgucuc caacauccac aacacgaccc     1560

gcaacaaccg cuacaagcug agcgacaccg ugcacuccaa guacggggcc agcuucgagu     1620

ucuacaacua cgcgugcaug uucauggacu acauguacaa caaggacaug ggcauccuca     1680

acaagcugaa cgaccuggcc aagaacaacg acgucgacgg cuacgacaac uacauccggg     1740

accuguccag caacuacgcc cucaacgaca aguaccagga ccacaugcag gagcgcaucg     1800

acaacuacga gaaccugacc gugcccuucg uggccgacga cuaccugguc cggcacgcgu     1860

acaagaaccc caacgagauc uacuccgaga ucagcgaggu ggccaagcuc aaggacgcca     1920

aguccgaggu gaagaagagc caguacuucu ccacguucac ccugcgcggg agcuacaccg     1980

gcggggccuc caagggcaag cuggaggacc agaaggccau gaacaaguuc aucgacgaca     2040

gccucaagaa gcuggacacc uacuccugga gcggguacaa gacccugacg gcguacuuca     2100

ccaacuacaa ggucgacucc agcaaccggg ugaccuacga cguggucuuc cacggcuacc     2160

uccccaacga gggcgacagc aagaacuccc ugccguacgg gaagaucaac ggcaccuaca     2220

aggggacgga gaaggagaag aucaaguuca gcuccgaggg cagcuucgac cccgacggca     2280

agaucguguc cuacgagugg gacuucgggg acggcaacaa gagcaacgag gagaaccccg     2340

agcacuccua cgacaaggug gggaccuaca ccgucaagcu gaaggugacc gacgacaagg     2400

gcgagagcuc cgugagcacg accaccgccg agaucaagga ccucuccgag aacaagcugc     2460

ccgucaucua caugcacgug ccgaagagcg gggcccugaa ccagaaggug gucuucuacg     2520

gcaagggcac cuacgacccc gacgggucca ucgccggcua ccagugggac uucggggacg     2580

gcagcgacuu cuccagcgag cagaaccccu cccacgugua cacgaagaag ggggaguaca     2640

ccgugacccu ccgcgucaug gacagcagcg gccagauguc cgagaagacc augaagauca     2700

agaucacgga cccgguguac cccaucggca ccgagaagga gcccaacaac agcaaggaga     2760

ccgccuccgg gcccaucgug ccgggcaucc ccgucagcgg gaccaucgag aacacguccg     2820

accaggacua cuucuacuuc gacgugauca cccccggcga ggugaagauc gacaucaaca     2880

agcuggggua cggcggcgcg accugggucg uguacgacga gaacaacaac gccgugagcu     2940

acgccaccga cgacgggcag aaccuguccg gcaaguucaa ggccgacaag cccgggcggu     3000

acuacaucca ccucuacaug uucaacggca gcuacaugcc guaccgcauc aacaucgagg     3060

gguccgucgg ccggugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  3913
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt1)

<400>  3913
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuc cuguucucca      120

gcgccuacuc caugaagcgc aagugccuga gcaagcggcu caugcuggcc aucaccaugg      180

ccaccaucuu cacggugaac uccacccugc ccaucuacgc ggccgucgac aagaacaacg      240

ccaccgccgc ccgccggcgc cggaagcgcg ugcagaacga gagcaagcgc uacaccgugu      300

ccuaccucaa gacgcugaac uacuacgacc uggucgaccu ccuggugaag accgagaucg      360

agaaccugcc cgaccucuuc caguacagcu ccgacgcgaa ggaguucuac ggcaacaaga      420

cccggaugag cuucaucaug gacgagaucg ggcgccgggc cccgcaguac accgagaucg      480

accacaaggg cauccccacg cugguggagg ucgugcgcgc cggguucuac cugggcuucc      540

acaacaagga gcucaacgag aucaacaagc gguccuucaa ggagcgcgug auccccagca      600

uccuggccau ccagaagaac ccgaacuuca agcuggggac cgagguccag gacaagaucg      660

uguccgcgac cggccuccug gccggcaacg agaccgcccc gcccgaggug gucaacaacu      720

ucacgcccau ccugcaggac ugcaucaaga acaucgaccg guacgcccuc gacgaccuga      780

agagcaaggc ccuguucaac gugcucgcgg ccccgaccua cgacaucacc gaguaccugc      840

gcgccaccaa ggagaagccc gagaacacgc cgugguacgg gaagaucgac ggcuucauca      900

acgagcugaa gaagcucgcc cuguacggga agaucaacga caacaacucc uggaucaucg      960

acaacggcau cuaccacauc gccccccugg ggaagcucca cagcaacaac aagaucggca     1020

ucgagacccu gaccgaggug augaaggucu acccguaccu guccaugcag caccuccaga     1080

gcgcggacca gaucaagcgg cacuacgacu ccaaggacgc cgagggcaac aagauccccc     1140

uggacaaguu caagaaggag gggaaggaga aguacugccc caagaccuac acguucgacg     1200

acggcaaggu gaucaucaag gccggggccc gcguggagga ggagaagguc aagcggcugu     1260

acugggccag caaggaggug aacucccagu ucuuccgcgu guacggcauc gacaagcccc     1320

ucgaggaggg caacccggac gacauccuga ccauggucau cuacaacagc cccgaggagu     1380

acaagcugaa cuccgugcuc uacggguacg acaccaacaa cggcgggaug uacaucgagc     1440

ccgagggcac cuucuucacg uacgagcggg aggcgcagga gagcaccuac acccuggagg     1500

agcuguuccg ccacgaguac acccacuacc uccaggggcg guacgccgug cccggccagu     1560

ggggccgcac gaagcuguac gacaacgacc ggcugaccug guacgaggag ggcggcgccg     1620

agcucuucgc cgggagcacc cgcaccuccg ggauccugcc gcggaagagc aucgucucca     1680

acauccacaa cacgacccgc aacaaccgcu acaagcugag cgacaccgug cacuccaagu     1740

acggggccag cuucgaguuc uacaacuacg cgugcauguu cauggacuac auguacaaca     1800

aggacauggg cauccucaac aagcugaacg accuggccaa gaacaacgac gucgacggcu     1860

acgacaacua cauccgggac cuguccagca acuacgcccu caacgacaag uaccaggacc     1920

acaugcagga gcgcaucgac aacuacgaga accugaccgu gcccuucgug gccgacgacu     1980

accugguccg gcacgcguac aagaacccca acgagaucua cuccgagauc agcgaggugg     2040

ccaagcucaa ggacgccaag uccgagguga agaagagcca guacuucucc acguucaccc     2100

ugcgcgggag cuacaccggc ggggccucca agggcaagcu ggaggaccag aaggccauga     2160

acaaguucau cgacgacagc cucaagaagc uggacaccua cuccuggagc ggguacaaga     2220

cccugacggc guacuucacc aacuacaagg ucgacuccag caaccgggug accuacgacg     2280

uggucuucca cggcuaccuc cccaacgagg gcgacagcaa gaacucccug ccguacggga     2340

agaucaacgg caccuacaag gggacggaga aggagaagau caaguucagc uccgagggca     2400

gcuucgaccc cgacggcaag aucguguccu acgaguggga cuucggggac ggcaacaaga     2460

gcaacgagga gaaccccgag cacuccuacg acaagguggg gaccuacacc gucaagcuga     2520

aggugaccga cgacaagggc gagagcuccg ugagcacgac caccgccgag aucaaggacc     2580

ucuccgagaa caagcugccc gucaucuaca ugcacgugcc gaagagcggg gcccugaacc     2640

agaagguggu cuucuacggc aagggcaccu acgaccccga cggguccauc gccggcuacc     2700

agugggacuu cggggacggc agcgacuucu ccagcgagca gaaccccucc cacguguaca     2760

cgaagaaggg ggaguacacc gugacccucc gcgucaugga cagcagcggc cagauguccg     2820

agaagaccau gaagaucaag aucacggacc cgguguaccc caucggcacc gagaaggagc     2880

ccaacaacag caaggagacc gccuccgggc ccaucgugcc gggcaucccc gucagcggga     2940

ccaucgagaa cacguccgac caggacuacu ucuacuucga cgugaucacc cccggcgagg     3000

ugaagaucga caucaacaag cugggguacg gcggcgcgac cugggucgug uacgacgaga     3060

acaacaacgc cgugagcuac gccaccgacg acgggcagaa ccuguccggc aaguucaagg     3120

ccgacaagcc cgggcgguac uacauccacc ucuacauguu caacggcagc uacaugccgu     3180

accgcaucaa caucgagggg uccgucggcc ggugaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  3914
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt1)

<400>  3914
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggccgcgu      120

ucgccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc agcuacgagg      180

ugcucacccc gcugaagugg uaccagucca uccgcccgcc cuaccccagc uacggcuacg      240

agcccauggg cggguggcug caccaccaga ucauccccgu ccucucccag cagcacccgc      300

ccacgcacac ccugcagccg caccaccaca uccccguggu gcccgcccag cagcccguca      360

ucccccagca gcccaugaug cccgugcccg gccagcacag caugaccccg auccagcacc      420

accagcccaa ccugcccccg ccggcccagc agcccuacca gccccagccc gugcagcccc      480

agccccacca gcccaugcag ccgcagccgc ccguccaccc caugcagccg cucccgcccc      540

agcccccgcu gccgcccaug uuccccaugc agccccugcc gcccaugcuc cccgaccuga      600

cccuggaggc cuggcccucc acggacaaga ccaagcggga ggagguggac ugaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  3915
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt1)

<400>  3915
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucagcuacga ggugcucacc ccgcugaagu gguaccaguc cauccgcccg cccuacccca      180

gcuacggcua cgagcccaug ggcggguggu gaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  3916
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt1)

<400>  3916
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucagcuacga ggugcucacc ccgcugaagu gguaccaguc cauccgcccg ccgcccaugc      180

uccccgaccu gacccuggag gccuggcccu ccacggacaa gaccaagcgg gaggaggugg      240

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  3917
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt1)

<400>  3917
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg ccccgcggac ccugguccuc cugcugagcg      120

gcgcgcucgc ccugacccag acgugggcca ugccccugcc gccccacccc ggccaccccg      180

gguacaucaa cuucagcuac gaggugcuca ccccgcugaa gugguaccag uccauccgcc      240

cgcccuaccc cagcuacggc uacgagccca ugggcgggug gugaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  3918
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt1)

<400>  3918
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg ccccgcggac ccugguccuc cugcugagcg      120

gcgcgcucgc ccugacccag acgugggcca ugccccugcc gccccacccc ggccaccccg      180

gguacaucaa cuucagcuac gaggugcuca ccccgcugaa gugguaccag uccauccgcc      240

cgccgcccau gcuccccgac cugacccugg aggccuggcc cuccacggac aagaccaagc      300

gggaggaggu ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  3919
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt1)

<400>  3919
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccucgug ggggccgcgu      120

ucgccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc agcuacgagg      180

uccugacccc gcucaagugg uaccagucca ugauccgccc gcccuacagc uccuacggcu      240

acgagcccau gggcgggugg cugcaccacc agaucauccc cguggugagc cagcagcacc      300

cccugacgca cacccuccag ucccaccacc acauccccgu cgugcccgcc cagcagccgc      360

gggugcgcca gcaggcccug augcccgucc ccggccagca gagcaugacc cccacccagc      420

accaccagcc gaaccugccc cuccccgccc agcagcccuu ccagccgcag cccgugcagc      480

cccagcccca ccagccgaug cagccccagc cgcccgugca gcccaugcag ccccugcugc      540

cccagccgcc ccucccgccc auguuccccc ugcggccccu gccgcccauc cuccccgacc      600

ugcaccugga ggcguggccc gccacggaca agaccaagca ggaggagguc gacugaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  3920
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt1)

<400>  3920
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucagcuacga gguccugacc ccgcucaagu gguaccaguc caugauccgc ccgcccuaca      180

gcuccuacgg cuacgagccc augggcgggu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  3921
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt1)

<400>  3921
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucagcuacga gguccugacc ccgcucaagu gguaccaguc caugauccgc ccgccgccca      180

uccuccccga ccugcaccug gaggcguggc ccgccacgga caagaccaag caggaggagg      240

ucgacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  3922
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt1)

<400>  3922
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg ccccgcggac ccugguccuc cugcugagcg      120

gcgcgcucgc ccugacccag acgugggcca ugccccugcc gccccacccc ggccaccccg      180

gguacaucaa cuucagcuac gagguccuga ccccgcucaa gugguaccag uccaugaucc      240

gcccgcccua cagcuccuac ggcuacgagc ccaugggcgg guggugagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  3923
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt1)

<400>  3923
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg ccccgcggac ccugguccuc cugcugagcg      120

gcgcgcucgc ccugacccag acgugggcca ugccccugcc gccccacccc ggccaccccg      180

gguacaucaa cuucagcuac gagguccuga ccccgcucaa gugguaccag uccaugaucc      240

gcccgccgcc cauccucccc gaccugcacc uggaggcgug gcccgccacg gacaagacca      300

agcaggagga ggucgacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  3924
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt1)

<400>  3924
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggccgcgu      120

ucagcaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacgagg      180

ugcucacccc gcugaagugg uaccagaaca ugauccgcca ccccuacacg agcuacggcu      240

acgagcccau gggcgggugg cugcaccacc agaucauccc cgucgugucc cagcagaccc      300

cgcagagcca cgcccuccag ccccaccacc acauccccau ggugcccgcc cagcagccgg      360

gcauccccca gcagcccaug augccccugc cggggcagca cuccaugacc cccacccagc      420

accaccagcc caaccugccc cucccggccc agcagcccuu ccagccccag cccguccagc      480

cgcagcccca ccagccccug cagccccaga gcccgaugca ccccauccag ccccugcucc      540

cgcagccgcc ccugcccccg auguucucca ugcagagccu gcuccccgac cugccccugg      600

aggccuggcc cgcgacggac aagaccaagc gggaggaggu ggacugagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  3925
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt1)

<400>  3925
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucuccuacga ggugcucacc ccgcugaagu gguaccagaa caugauccgc caccccuaca      180

cgagcuacgg cuacgagccc augggcgggu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  3926
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt1)

<400>  3926
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucuccuacga ggugcucacc ccgcugaagu gguaccagaa caugauccgc caccccagcc      180

ugcuccccga ccugccccug gaggccuggc ccgcgacgga caagaccaag cgggaggagg      240

uggacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  3927
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt1)

<400>  3927
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg ccccgcggac ccugguccuc cugcugagcg      120

gcgcgcucgc ccugacccag acgugggcca ugccccugcc gccccacccc ggccaccccg      180

gguacaucaa cuucuccuac gaggugcuca ccccgcugaa gugguaccag aacaugaucc      240

gccaccccua cacgagcuac ggcuacgagc ccaugggcgg guggugagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  3928
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt1)

<400>  3928
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg ccccgcggac ccugguccuc cugcugagcg      120

gcgcgcucgc ccugacccag acgugggcca ugccccugcc gccccacccc ggccaccccg      180

gguacaucaa cuucuccuac gaggugcuca ccccgcugaa gugguaccag aacaugaucc      240

gccaccccag ccugcucccc gaccugcccc uggaggccug gcccgcgacg gacaagacca      300

agcgggagga gguggacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  3929
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt1)

<400>  3929
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggccgcgu      120

ucagcaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacaucc      180

gccacccgua caccagcuac ggcuacgagc ccaugggcgg guggcuccac caccagauca      240

uccccguggu cucccagcag acgccccaga gccacgcccu gcagccgcac caccacaucc      300

ccauggugcc cgcccagcag cccggcaucc cgcagcagcc caugaugccc cugcccgggc      360

agcacuccau gaccccgacc cagcaccacc agcccaaccu cccccugccc gcccagcagc      420

cguuccagcc ccagcccgug cagccccagc cgcaccagcc ccugcagccc cagagcccca      480

ugcacccgau ccagccccuc cugccccagc cgccccugcc gcccauguuc uccaugcaga      540

gccuccugcc cgaccugccc cucgaggccu ggcccgcgac cgacaagacg aagcgggagg      600

aggucgacug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  3930
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt1)

<400>  3930
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuucgc cugccugcuc ggggccagcc      120

uggcgaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacgagg      180

ugcucacgcc ccugaagugg uaccagaaca ugauccgcca ccccuacacc agcuacggcu      240

acgagcccau gggcgggugg cugcaccacc agaucauccc cgucgugucc cagcagaccc      300

cgcagagcca cgcccuccag ccccaccacc acauccccau ggugcccgcc cagcagccgg      360

gcauccccca gcagcccaug augccccugc cggggcagca cuccaugacc cccacccagc      420

accaccagcc caaccugccc cucccggccc agcagcccuu ccagccccag cccguccagc      480

cgcagcccca ccagccccug cagccccaga gcccgaugca ccccauccag ccccugcucc      540

cgcagccgcc ccugccgccc auguucucca ugcagagccu gcuccccgac cugccccugg      600

aggccuggcc cgcgacggac aagaccaagc gggaggaggu ggacugagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  3931
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt1)

<400>  3931
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggccgcgu      120

ucagcaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacgagg      180

ugcucacccc gcugaagugg uaccagaaca ugauccgcca ccccagccug cuccccgacc      240

ugccccugga ggccuggccg gccacggaca agaccaagcg ggaggagguc gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  3932
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt1)

<400>  3932
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggccgcgu      120

ucagcaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacgagg      180

accucuaccu ggaggccauc cgcaucgacc ggaccgccuu cgugcugacg ccccucaagu      240

gguaccagaa caugauccgc caccccuaca ccagcuacgg cuacgagccc augggcgggu      300

ggcugcacca ccagaucauc cccgucgugu cccagcagac cccgcagagc cacgcccugc      360

agccccacca ccacaucccc auggugcccg cccagcagcc gggcaucccc cagcagccca      420

ugaugccccu cccggggcag cacuccauga cccccacgca gcaccaccag cccaaccugc      480

cccugccggc gcagcagccc uuccagcccc agcccgucca gccgcagccc caccagcccc      540

uccagcccca gagcccgaug caccccaucc agccccugcu gccgcagccg ccccugccgc      600

ccauguucuc caugcagagc cuccugcccg accucccccu ggaggccugg cccgccaccg      660

acaagaccaa gcgggaggag guggacugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  3933
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt1)

<400>  3933
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggccgcgu      120

ucagcaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacgagg      180

ugcucacccc gcugaagugg uaccagaaca ugauccgcca ccccacgccc cagagccacg      240

cccugcagcc ccaccaccac aucccgaugg uccccgccca gcagcccggc aucccccagc      300

agccgaugau gccccucccc gggcagcacu ccaugacccc cacccagcac caccagccga      360

accugccccu gcccgcccag cagcccuucc agccgcagcc cgugcagccc cagccccacc      420

agccgcucca gccccagagc cccaugcacc ccauccagcc gcugcugccc cagcccccgc      480

ucccgcccau guucuccaug cagagccugc ugcccgaccu cccccuggag gccuggcccg      540

cgaccgacaa gacgaagcgg gaggaggugg acugaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  3934
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt1)

<400>  3934
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucagcuacga ggugcucacc ccgcugaagu gguaccagaa caugauccgc caccccuaca      180

ccuccuacgg cuacgagccc augggcgggu ggcugcacca ccagaucauc cccgucguga      240

gccagcagac gccgcagucc cacgcccucc agccccacca ccacaucccc auggugcccg      300

cccagcagcc cgggaucccc cagcagccca ugaugccccu gccgggccag cacagcauga      360

cccccaccca gcaccaccag cccaaccugc cccucccggc gcagcagccc uuccagcccc      420

agcccgucca gccgcagccc caccagcccc ugcagcccca guccccgaug caccccaucc      480

agccccugcu cccgcagccg ccccugccgc ccauguucag caugcagucc cugcuccccg      540

accugccccu ggaggccugg cccgccaccg acaagacgaa gcgggaggag guggacugag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  3935
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt1)

<400>  3935
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg cccgccugcc gcuccugcug gggcuccugc      120

ugcucccccg gcccggccgc ccccuggacc uggccgacua caccuacgac cucgccgagg      180

aggacgacag cgagccgcug aacuacaagg accccugcaa ggccgccgcc uuccuggggg      240

acaucgcccu cgacgaggag gaccugcggg cguuccaggu ccagcaggcc guggaccugc      300

gccggcacac cgcccgcaag uccagcauca aggccgcggu gcccggcaac acguccaccc      360

ccagcugcca guccaccaac gggcagccgc agcggggcgc cugcggccgc uggcgggggc      420

gcagccgguc ccgccgggcc gccaccagcc gccccgagcg ggucuggccc gacggcguga      480

uccccuucgu gaucgggggc aacuucacgg ggucccagcg cgccgucuuc cggcaggcga      540

ugcgccacug ggagaagcac acgugcguga ccuuccucga gcggaccgac gaggacagcu      600

acaucguguu caccuaccgc ccgugcggcu gcugcuccua cgucggccgg cgcgggggcg      660

ggccccaggc caucagcauc ggcaagaacu gcgacaaguu cggcaucgug gugcacgagc      720

uggggcacgu cgugggcuuc uggcacgagc acacccgccc cgaccgggac cgccacgugu      780

ccaucguccg ggagaacauc cagcccgggc aggaguacaa cuuccugaag auggagccgc      840

aggaggugga gagccucggc gagaccuacg acuucgacuc caucaugcac uacgcccgca      900

acaccuucag ccgggggauc uuccuggaca cgaucgugcc caaguacgag gucaacggcg      960

ugaagccgcc caucggccag cgcacccggc uguccaaggg ggacaucgcc caggcccgca     1020

agcucuacaa gugccccgcg ugcggcgaga cccugcagga cagcaccggg aacuucucca     1080

gccccgagua ccccaacggc uacagcgccc acaugcacug cguguggcgg aucuccguca     1140

cgcccgggga gaagaucauc cugaacuuca ccagccucga ccuguaccgc ucccggcugu     1200

gcugguacga cuacguggag gugcgcgacg gcuucuggcg gaaggccccg cuccgcggcc     1260

gguucugcgg gagcaagcug cccgagccca ucgucuccac cgacagccgc cugugggugg     1320

aguuccgguc cagcuccaac ugggucggca agggguucuu cgccguguac gaggccaucu     1380

gcggcgggga cgugaagaag gacuacggcc acauccagag ccccaacuac ccggacgacu     1440

accgccccuc caaggucugc aucuggcgga uccaggugag cgagggcuuc cacguggggc     1500

ucaccuucca guccuucgag aucgagcgcc acgacagcug cgcguacgac uaccuggagg     1560

uccgcgacgg ccacuccgag agcuccacgc ugaucgggcg guacugcggc uacgagaagc     1620

ccgacgacau caagagcacc uccagccgcc ucuggcugaa guucgugagc gacggcucca     1680

ucaacaaggc cggguucgcc gugaacuucu ucaaggaggu cgacgagugc agccggccga     1740

accgcggcgg gugcgagcag cggugccuga acacccucgg cuccuacaag ugcagcugcg     1800

accccgggua cgagcuggcc cccgacaagc gccggugcga ggccgcgugc ggcggcuucc     1860

ugaccaagcu caacgggucc aucacgagcc ccggcuggcc gaaggaguac ccgcccaaca     1920

agaacugcau cuggcagcug guggccccca cccaguaccg caucucccug caguucgacu     1980

ucuucgagac cgaggggaac gacgugugca aguacgacuu cgucgaggug cggagcggcc     2040

ucaccgccga cuccaagcug cacgggaagu ucugcggcag cgagaagccc gaggugauca     2100

cgucccagua caacaacaug cgcgucgagu ucaagagcga caacaccgug uccaagaagg     2160

gcuucaaggc ccacuucuuc agcgacaagg acgagugcuc caaggacaac gggggcugcc     2220

agcaggacug cgugaacacc uucgggagcu acgagugcca gugccggucc ggcuucgucc     2280

ugcacgacaa caagcacgac ugcaaggagg cggggugcga ccacaaggug accagcacga     2340

gcggcaccau caccuccccc aacuggcccg acaaguaccc cagcaagaag gagugcaccu     2400

gggccaucuc cagcacgccg ggccaccgcg ugaagcucac cuucauggag auggacaucg     2460

agucccagcc cgagugcgcc uacgaccacc uggaggucuu cgacgggcgg gacgccaagg     2520

cccccgugcu gggccgcuuc ugcgggagca agaagcccga gccggugcuc gcgaccggcu     2580

cccggauguu ccugcgcuuc uacagcgaca acuccgucca gcggaagggg uuccaggcca     2640

gccacgccac cgagugcggc ggccaggugc gcgccgacgu gaagaccaag gaccuguacu     2700

cccacgccca guucggggac aacaacuacc ccggcggggu cgacugcgag ugggugaucg     2760

uggcggagga gggcuacggc gucgagcugg uguuccagac guucgaggug gaggaggaga     2820

ccgacugcgg guacgacuac auggagcugu ucgacggcua cgacagcacc gcgccccggc     2880

ucgggcgcua cugcggcucc gggcccccgg aggaggucua cagcgccggc gacuccgugc     2940

uggugaaguu ccacagcgac gacaccauca cgaagaaggg cuuccaccuc cgguacaccu     3000

ccaccaaguu ccaggacacc cugcacagcc gcaagugagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  3936
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt1)

<400>  3936
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggca cccgcugccu gcucgcccug cugcuccccc      120

agguccugcu cgggggcgcg gccgggcugg ugccggagcu gggccggcgc aaguucgccg      180

ccgccagcuc cgggcggccc agcucccagc ccagcgacga ggugcugucc gaguucgagc      240

uccgccugcu gagcauguuc ggccucaagc agcggcccac cccgucccgc gacgcggucg      300

ugccgcccua caugcuggac cuguaccggc gccacagcgg ccagcccggg ucccccgccc      360

ccgaccaccg gcucgagcgc gccgccagcc gggcgaacac ggugcgcucc uuccaccacg      420

aggagagccu ggaggagcug cccgagaccu ccggcaagac cacccggcgc uucuucuuca      480

accucagcuc cauccccacg gaggaguuca ucaccagcgc cgagcugcag gucuuccggg      540

agcagaugca ggacgcccug gggaacaacu ccagcuucca ccaccgcauc aacaucuacg      600

agaucaucaa gccggccacc gccaacucca aguuccccgu gacccggcuc cuggacacgc      660

gccuggugaa ccagaacgcg agccgguggg agagcuucga cgucaccccc gccgugaugc      720

gcuggaccgc ccagggccac gccaaccacg gguucguggu cgagguggcc caccucgagg      780

agaagcaggg cguguccaag cggcacgucc gcaucagccg cucccugcac caggacgagc      840

acagcugguc ccagauccgg ccccugcucg ugaccuucgg ccacgacggg aagggccacc      900

cgcugcacaa gcgcgagaag cggcaggcga agcacaagca gcgcaagcgg cucaagagcu      960

ccugcaagcg ccacccccug uacguggacu ucagcgacgu cggguggaac gacuggaucg     1020

uggccccgcc cggcuaccac gccuucuacu gccacggcga gugccccuuc ccccuggccg     1080

accaccugaa cuccacgaac cacgccaucg ugcagacccu cgucaacagc gugaacucca     1140

agauccccaa ggcgugcugc gugcccaccg agcugagcgc caucuccaug cuguaccucg     1200

acgagaacga gaaggucgug cugaagaacu accaggacau ggucguggag gggugcggcu     1260

gccggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  3937
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt1)

<400>  3937
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auccccggca accgcaugcu gauggugguc cuccugugcc      120

aggugcugcu cgggggcgcc agccacgccu cccugauccc ggagaccggg aagaagaagg      180

uggcggagau ccagggccac gccgggggcc ggcgcagcgg ccagucccac gagcugcucc      240

gggacuucga ggccacccug cugcagaugu ucgggcuccg ccggcgcccc cagcccagca      300

aguccgccgu cauccccgac uacaugcggg accuguaccg ccugcagagc ggcgaggagg      360

aggaggagca gauccacucc acggggcucg aguacccgga gcggcccgcc agccgcgcga      420

acaccgugcg guccuuccac cacgaggagc accuggagaa cauccccggc accagcgaga      480

acuccgccuu ccgcuuccug uucaaccuca gcuccauccc cgagaacgag gugaucagcu      540

ccgccgagcu gcggcuguuc cgcgagcagg ucgaccaggg gccggacugg gagcggggcu      600

uccaccgcau caacaucuac gaggugauga agccgcccgc cgaggugguc cccggccacc      660

ucaucacccg gcugcuggac acgcgccucg ugcaccacaa cgugacccgg ugggagaccu      720

ucgacgucag ccccgcggug cugcgcugga cccgggagaa gcagcccaac uacgggcugg      780

ccaucgaggu gacgcaccuc caccagaccc gcacccacca gggccagcac guccgcaucu      840

cccggagccu gccccagggg uccggcaacu gggcccagcu gcgcccccuc cuggugaccu      900

ucggccacga cgggcggggc cacgcccuga cgcgccggcg ccgggccaag cgcagcccga      960

agcaccacag ccagcgggcg cgcaagaaga acaagaacug ccggcgccac ucccucuacg     1020

uggacuucag cgacgucggg uggaacgacu ggaucguggc cccgcccggc uaccaggccu     1080

ucuacugcca cggggacugc cccuuccccc uggccgacca ccugaacucc accaaccacg     1140

ccaucgugca gacccucguc aacagcguga acuccagcau ccccaaggcg ugcugcgugc     1200

ccaccgagcu guccgccauc agcaugcugu accucgacga guacgacaag gucgugcuga     1260

agaacuacca ggagaugguc guggagggcu gcggcugccg gugaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  3938
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt1)

<400>  3938
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggccugg ggcgccgggc ccaguggcuc ugcugguggu      120

ggggccugcu gugcagcugc ugcgggccgc cgccccuccg gccgccccug cccgccgcgg      180

ccgccgccgc cgcgggcggg cagcugcucg gcgacggcgg gucccccggc cggaccgagc      240

agcccccgcc cagcccccag uccagcuccg gguuccugua ccgccggcug aagacccagg      300

agaagcgcga gaugcagaag gagauccuca gcgugcuggg ccugccccac cggccccgcc      360

cccuccacgg gcugcagcag ccccagcccc cggcccugcg gcagcaggag gagcagcagc      420

agcagcagca gcucccccgc ggcgagcccc cgcccggccg gcugaagucc gcgccccugu      480

ucaugcucga ccuguacaac gcccugagcg ccgacaacga cgaggacggg gccuccgagg      540

gcgagcgcca gcagagcugg ccccacgagg ccgccuccag cucccagcgg cgccagcccc      600

cgcccggggc cgcgcacccc cucaaccgca agagccugcu ggcccccggc uccggcagcg      660

ggggcgccuc cccgcucacg agcgcccagg acuccgccuu ccugaacgac gcggacaugg      720

ucaugagcuu cgugaaccug guggaguacg acaaggaguu cagcccccgc cagcggcacc      780

acaaggaguu caaguucaac cucucccaga uccccgaggg ggaggucgug accgccgccg      840

aguuccgcau cuacaaggac ugcgugaugg gcagcuucaa gaaccagacc uuccugaucu      900

ccaucuacca gguccugcag gagcaccagc accgggacag cgaccucuuc cugcuggaca      960

cccgcguggu gugggccucc gaggaggggu ggcucgaguu cgacaucacg gccaccagca     1020

accugugggu cgugaccccg cagcacaaca ugggccugca gcucuccgug gucacccggg     1080

acggcgugca cgugcacccc cgcgcggccg ggcuggucgg ccgcgacggg cccuacgaca     1140

agcagcccuu caugguggcc uucuucaagg ugagcgaggu ccacgugcgg acgacccgcu     1200

ccgccagcuc ccggcgccgg cagcagagcc gcaaccgguc cacccagagc caggacgugg     1260

cccgcgucuc cagcgcgucc gacuacaaca gcuccgagcu gaagaccgcc ugccggaagc     1320

acgagcucua cgugagcuuc caggaccugg gcuggcagga cuggaucauc gccccgaagg     1380

gguacgccgc gaacuacugc gacggcgagu gcagcuuccc ccugaacgcc cacaugaacg     1440

ccacgaacca cgccaucgug cagacccucg uccaccugau gaaccccgag uacgugccca     1500

agccgugcug cgcccccacc aagcugaacg cgaucuccgu ccucuacuuc gacgacaaca     1560

gcaacgugau ccugaagaag uaccgcaaca uggugguccg ggccugcggc ugccacugag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  3939
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt1)

<400>  3939
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugcgca gccugcgggc cgccgcgccc cacuccuucg      120

ucgcccucug ggccccgcug uuccugcucc gcagcgcccu ggccgacuuc ucccuggaca      180

acgaggugca cagcuccuuc auccaccggc gccuccggag ccaggagcgc cgggagaugc      240

agcgcgagau ccuguccauc cugggccucc cccaccggcc ccgcccccac cuccagggga      300

agcacaacag cgcgccgaug uucaugcugg accuguacaa cgccauggcc guggaggagg      360

gcgggggccc cgggggccag ggcuucuccu accccuacaa ggccgucuuc agcacccagg      420

ggcccccgcu ggcgucccug caggacagcc acuuccucac cgacgccgac auggugaugu      480

ccuucgugaa ccuggucgag cacgacaagg aguucuucca cccccgguac caccaccgcg      540

aguuccgguu cgaccugagc aagauccccg agggcgaggc cgugacggcc gccgaguucc      600

gcaucuacaa ggacuacauc cgggagcgcu ucgacaacga gaccuuccgg aucuccgugu      660

accagguccu ccaggagcac cuggggcgcg agagcgaccu guuccuccug gacucccgga      720

cccugugggc gagcgaggag ggcuggcucg uguucgacau caccgccacg uccaaccacu      780

ggguggucaa cccccgccac aaccuggggc ugcagcucag cguggagacc cuggacggcc      840

agagcaucaa cccgaagcug gccggccuca ucgggcggca cggcccccag aacaagcagc      900

ccuucauggu ggccuucuuc aaggccaccg agguccacuu ccgcuccauc cgcagcaccg      960

gguccaagca gcggagccag aaccgcucca agacgcccaa gaaccaggag gcgcugcgga     1020

uggccaacgu ggccgagaac agcuccagcg accagcgcca ggccugcaag aagcacgagc     1080

uguacguguc cuuccgggac cucggcuggc aggacuggau caucgccccg gagggcuacg     1140

cggccuacua cugcgagggg gagugcgccu ucccccugaa cagcuacaug aacgccacca     1200

accacgccau cguccagacc cuggugcacu ucaucaaccc cgagaccgug cccaagccgu     1260

gcugcgcgcc cacgcagcuc aacgccaucu ccguccugua cuucgacgac agcuccaacg     1320

ugauccugaa gaaguaccgc aacauggugg uccgggccug cggcugccac ugaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  3940
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt1)

<400>  3940
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggccagcg ccgcgcugcu cugccugcug cucaccgccg      120

ccgccuucag cccccagggc cuggcccagc cgguggggau caacaccucc acgaccugcu      180

gcuaccgcuu caucaacaag aagaucccca agcagcggcu ggaguccuac cgccggacca      240

ccagcuccca cugcccccgc gaggcgguca ucuucaagac gaagcucgac aaggagaucu      300

gcgccgaccc cacccagaag ugggugcagg acuucaugaa gcaccuggac aagaagaccc      360

agaccccgaa gcugugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  3941
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt1)

<400>  3941
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucaccc ugaucauccu gcuccccgug gucagcaagu      120

ucuccuucgu gagccugucc gcgccccagc acuggagcug ccccgagggc acccuggccg      180

ggaacggcaa cuccacgugc guggggcccg cccccuuccu caucuucagc cacggcaacu      240

ccaucuuccg caucgacacc gaggggacca acuacgagca gcuggucgug gacgccggcg      300

ugagcgucau cauggacuuc cacuacaacg agaagcggau cuacugggug gaccuggagc      360

gccagcuccu gcagcgggug uuccugaacg gcucccgcca ggagcggguc ugcaacaucg      420

agaagaacgu gagcgggaug gccaucaacu ggaucaacga ggaggugauc ugguccaacc      480

agcaggaggg caucaucacc gucacggaca ugaaggggaa caacagccac auccuccugu      540

ccgcccugaa guacccggcc aacguggcgg uggaccccgu cgagcgcuuc aucuucugga      600

gcuccgaggu ggccggcagc cucuaccggg ccgaccugga cggggugggc gucaaggccc      660

ugcucgagac cuccgagaag aucaccgcgg ugagccugga cgugcuggac aagcgccucu      720

ucuggaucca guacaaccgg gagggcucca acagccugau cugcagcugc gacuacgacg      780

ggggcuccgu ccacaucagc aagcacccca cccagcacaa ccuguucgcc augucccucu      840

ucggggaccg caucuucuac agcacgugga agaugaagac caucuggauc gccaacaagc      900

acaccggcaa ggacauggug cggaucaacc ugcacuccag cuucgugccc cugggcgagc      960

ucaaggucgu gcacccgcug gcccagccca aggccgagga cgacaccugg gagcccgagc     1020

agaagcugug caagcuccgc aaggggaacu gcuccagcac ggucugcggc caggaccugc     1080

agucccaccu gugcaugugc gcggaggggu acgcccucag ccgggaccgc aaguacugcg     1140

aggacgugaa cgagugcgcc uucuggaacc acggcugcac ccuggggugc aagaacaccc     1200

ccggcuccua cuacugcacg ugcccggugg gcuucguccu gcuccccgac gggaagcggu     1260

gccaccagcu ggugagcugc ccccgcaacg uguccgagug cagccacgac ugcguccuga     1320

ccuccgaggg cccccucugc uucugcccgg aggggagcgu gcuggagcgg gacggcaaga     1380

ccugcuccgg gugcagcucc cccgacaacg gcggcugcag ccagcugugc gugccccuca     1440

gccccgucuc cugggagugc gacugcuucc cgggguacga ccugcagcug gacgagaagu     1500

ccugcgccgc cagcggcccc cagcccuucc uccuguucgc gaacagccag gacauccgcc     1560

acaugcacuu cgacgggacc gacuacggca cccugcucuc ccagcagaug gggauggugu     1620

acgcccugga ccacgacccc guggagaaca agaucuacuu cgcccacacg gcccugaagu     1680

ggaucgagcg ggccaacaug gacggcagcc agcgcgagcg gcugaucgag gagggcgucg     1740

acgugccgga ggggcucgcg guggacugga ucggccgccg cuucuacugg accgaccggg     1800

ggaagucccu gaucggccgc agcgaccuga acggcaagcg guccaagauc aucaccaagg     1860

agaacaucag ccagccccgc gggaucgccg uccaccccau ggccaagcgc cucuucugga     1920

ccgacacggg caucaacccc cggaucgagu ccagcucccu gcaggggcug ggccggcucg     1980

ugaucgccag cuccgaccug aucuggccga gcgggaucac caucgacuuc cugaccgaca     2040

agcucuacug gugcgacgcc aagcaguccg ugaucgagau ggcgaaccug gacggcagca     2100

agcgccggcg ccugacccag aacgacgucg gccaccccuu cgccguggcc guguucgagg     2160

acuacgucug guucagcgac ugggccaugc ccuccgugau gcgggugaac aagcgcacgg     2220

ggaaggaccg gguccgccuc cagggcagca ugcugaagcc guccagccug gugguggucc     2280

acccccucgc gaagcccggg gccgaccccu gccuguacca gaacggcggg ugcgagcaca     2340

ucugcaagaa gcggcugggc accgccuggu gcuccugccg cgagggcuuc augaaggcca     2400

gcgacgggaa gaccugccuc gcccuggacg gccaccagcu gcucgccggg ggcgaggugg     2460

accugaagaa ccaggugacc ccgcuggaca uccucuccaa gacgcggguc agcgaggaca     2520

acaucaccga gucccagcac augcuggugg ccgagaucau ggugagcgac caggacgacu     2580

gcgcccccgu cgggugcucc auguacgccc gcugcaucag cgagggcgag gacgcgaccu     2640

gccagugccu gaagggcuuc gcgggggacg gcaagcucug cuccgacauc gacgagugcg     2700

agaugggggu gcccgugugc ccgccggcca gcuccaagug caucaacacc gagggcgggu     2760

acgucugccg gugcagcgag ggcuaccagg gcgacgggau ccacugccug gacaucgacg     2820

agugccagcu gggcgagcac uccugcgggg agaacgccag cugcacgaac accgagggcg     2880

gcuacacgug caugugcgcc gggcgccucu ccgagcccgg ccugaucugc cccgacagca     2940

cgcccccgcc ccaccuccgc gaggacgacc accacuacag cgugcggaac uccgacagcg     3000

agugcccccu gucccacgac ggguacugcc ugcacgacgg cgugugcaug uacaucgagg     3060

cccuggacaa guacgcgugc aacugcgucg ugggguacau cggcgagcgc ugccaguacc     3120

gggaccucaa guggugggag cugcgccacg ccggccacgg gcagcagcag aaggugaucg     3180

ucguggccgu gugcgucgug gugcugguca ugcuccugcu gcucagccug uggggcgccc     3240

acuacuaccg gacccagaag cugcucucca agaaccccaa gaacccguac gaggagagcu     3300

cccgcgacgu gcggagccgc cggcccgcgg acaccgagga cgggaugucc agcugccccc     3360

agcccugguu cguggucauc aaggagcacc aggaccugaa gaacggcggg cagccggugg     3420

ccggcgagga cggccaggcc gccgacgggu ccaugcagcc caccagcugg cgccaggagc     3480

cccagcugug cggcaugggg accgagcagg gcugcuggau ccccgucucc agcgacaagg     3540

gguccugccc ccaggugaug gagcggagcu uccacaugcc cuccuacggc acccagaccc     3600

ucgagggcgg gguggagaag ccccacagcc ugcuguccgc caacccgcuc uggcagcagc     3660

gcgcgcugga cccgccccac cagauggagc ugacccagug aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  3942
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt1)

<400>  3942
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggcc gccggaugga gaugcugugc gccgggcgcg      120

ugcccgcgcu ccugcugugc cucggcuucc accuccugca ggccguccug agcaccacgg      180

ugaucccguc cugcaucccc ggggagagcu ccgacaacug caccgcccug gugcagaccg      240

aggacaaccc ccgggucgcc caggugagca ucaccaagug cuccagcgac augaacggcu      300

acugccugca cgggcagugc aucuaccucg uggacauguc ccagaacuac ugccgcugcg      360

aggucggcua cacgggcgug cggugcgagc acuucuuccu gaccgugcac cagccccuga      420

gcaaggagua cgucgcccuc accgugaucc ugaucauccu guuccucauc accguggucg      480

gguccacgua cuacuucugc cgcugguacc ggaaccgcaa gagcaaggag ccgaagaagg      540

aguacgagcg ggugaccucc ggcgaccccg agcugcccca ggugugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  3943
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt1)

<400>  3943
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgagggcg agaucaccac cuucacggcc cugaccgaga      120

aguucaaccu gcccccgggg aacuacaaga agcccaagcu ccuguacugc agcaacggcg      180

ggcacuuccu ccgcauccug cccgacggca ccguggacgg gacccgggac cgcuccgacc      240

agcacaucca gcugcagcuc agcgcggagu ccgucggcga gguguacauc aagagcacgg      300

agaccggcca guaccuggcc auggacaccg acgggcugcu cuacggcucc cagaccccca      360

acgaggagug ccuguuccug gagcggcucg aggagaacca cuacaacacg uacaucagca      420

agaagcacgc cgagaagaac ugguucgugg ggcugaagaa gaacggcucc ugcaagcgcg      480

ggccgcggac ccacuacggc cagaaggcca uccuguuccu cccccugccc gucagcuccg      540

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  3944
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt1)

<400>  3944
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggcgucg ggggcgggga cguggaggac gugaccccgc      120

gcccgggcgg gugccagauc agcggccggg gcgcccgcgg gugcaacggc auccccgggg      180

ccgcggccug ggaggccgcc cugccccggc gccggccccg ccggcacccg uccgucaacc      240

cccgcagccg ggccgcgggc agcccccgca cccgggggcg ccggacggag gagcgccccu      300

ccggcucccg gcucggcgac cgcgggcggg gccgcgcccu gcccgggggc cggcugggcg      360

ggcgcggccg ggggcgcgcc cccgagcgcg ugggcgggcg gggccgcggc cgggggaccg      420

ccgcgccccg cgccgccccc gccgcccggg gcagccgccc ggggcccgcg ggcaccaugg      480

ccgccggguc caucaccacg cuccccgccc ugcccgagga cggcggcagc ggggccuucc      540

cgcccggcca cuucaaggac cccaagcggc uguacugcaa gaacgggggc uucuuccucc      600

gcauccaccc cgacgggcgg guggacggcg uccgcgagaa guccgacccg cacaucaagc      660

ugcagcugca ggcggaggag cggggcgugg ugagcaucaa gggggucugc gccaaccgcu      720

accucgccau gaaggaggac ggccggcugc uggccuccaa gugcgugacc gacgagugcu      780

ucuucuucga gcgccucgag agcaacaacu acaacaccua ccggucccgc aaguacacca      840

gcugguacgu ggcccugaag cggacggggc aguacaagcu gggcuccaag accggccccg      900

ggcagaaggc gauccucuuc cugcccauga gcgccaaguc cugaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  3945
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt1)

<400>  3945
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uccugaccug gauccucccc acccugcugu      120

accgcagcug cuuccacauc aucugccucg ugggcacgau cucccuggcc ugcaacgaca      180

ugaccccgga gcagauggcc accaacguca acugcagcuc ccccgagcgg cacacccgca      240

gcuacgacua cauggagggc ggggacaucc gggugcgccg gcuguucugc cgcacgcagu      300

gguaccuccg gaucgacaag cgcgggaagg ugaagggcac ccaggagaug aagaacaacu      360

acaacaucau ggagauccgg accgucgcgg uggggaucgu ggccaucaag ggcgucgagu      420

ccgaguucua ccuggccaug aacaaggagg gcaagcugua cgccaagaag gagugcaacg      480

aggacugcaa cuucaaggag cucauccugg agaaccacua caacaccuac gccagcgcga      540

aguggacgca caacgggggc gagauguucg uggcccugaa ccagaagggg auccccgugc      600

gcggcaagaa gaccaagaag gagcagaaga ccgcccacuu ccuccccaug gccaucaccu      660

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  3946
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt1)

<400>  3946
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugcucc ccagcguggu ccugaagcug uuccucgccg      120

ccgugcuguc cgcgcuggug accggcgaga gccucgagcg gcugcggcgc gggcuggccg      180

ccggcaccuc caacccggac ccgcccacgg ucagcaccga ccagcuccug ccccucgggg      240

gcgggcggga ccgcaaggug cgggaccugc aggaggccga ccuggaccug cuccgcguga      300

cccuguccag caagccccag gcccuggcga cccccaacaa ggaggagcac ggcaagcgga      360

agaagaaggg caaggggcuc ggcaagaagc gcgaccccug ccugcggaag uacaaggacu      420

ucugcaucca cggggagugc aaguacguca aggagcugcg cgcccccucc ugcaucugcc      480

acccgggcua ccacggggag cggugccacg gccucagccu gcccguggag aaccgccugu      540

acacguacga ccacaccacc auccucgccg uggucgccgu ggugcugucc agcgucugcc      600

ugcucgugau cgugggccug cugauguucc gguaccaccg ccgcgggggc uacgacgucg      660

agaacgagga gaaggugaag cucgggauga ccaacuccca cugaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  3947
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt1)

<400>  3947
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccugcug cuccagcacg      120

uccugcugca ccuccugcug cucccgaucg ccauccccua cgcggagggc cagcgcaagc      180

ggcgcaacac cauccacgag uucaagaagu ccgccaagac gacccugauc aagaucgacc      240

ccgcccugaa gaucaagacc aagaagguga acaccgccga ccagugcgcc aaccggugca      300

cgcgcaacaa ggggcucccc uucacgugca aggcguucgu guucgacaag gcccggaagc      360

agugccugug guucccguuc aacagcauga gcuccggcgu caagaaggag uucgggcacg      420

aguucgaccu guacgagaac aaggacuaca uccgcaacug caucaucggc aaggggcgga      480

gcuacaaggg caccgugucc aucaccaaga gcggcaucaa gugccagccc ugguccagca      540

ugauccccca cgagcacucc uuccucccca gcuccuaccg cgggaaggac cugcaggaga      600

acuacugccg gaacccgcgc ggcgaggagg gcgggcccug gugcuucacc agcaaccccg      660

aggugcggua cgaggucugc gacauccccc agugcuccga gguggagugc augaccugca      720

acggggagag cuaccgcggc cugauggacc acaccgaguc cggcaagauc ugccagcggu      780

gggaccacca gaccccgcac cgccacaagu uccuccccga gcgguacccc gacaaggggu      840

ucgacgacaa cuacugccgc aaccccgacg gccagccgcg gcccuggugc uacacgcugg      900

acccccacac ccgcugggag uacugcgcca ucaagaccug cgccgacaac accaugaacg      960

acacggacgu gccccuggag accaccgagu gcauccaggg gcagggcgag ggcuaccggg     1020

ggaccgucaa cacgaucugg aacggcaucc cgugccagcg cugggacagc caguaccccc     1080

acgagcacga caugaccccc gagaacuuca agugcaagga ccuccgggag aacuacugcc     1140

gcaaccccga cggguccgag agcccguggu gcuucaccac cgaccccaac auccgcgugg     1200

gcuacugcuc ccagaucccc aacugcgaca ugagccacgg gcaggacugc uaccggggca     1260

acggcaagaa cuacaugggg aaccugagcc agacgcgcuc cggccugacc ugcagcaugu     1320

gggacaagaa cauggaggac cuccaccggc acaucuucug ggagcccgac gcguccaagc     1380

ugaacgagaa cuacugccgc aacccggacg acgacgccca cgggcccugg ugcuacaccg     1440

gcaacccccu gaucccgugg gacuacugcc ccaucagccg gugcgagggg gacaccacgc     1500

ccaccaucgu gaaccucgac caccccguca ucuccugcgc caagaccaag cagcugcgcg     1560

uggugaacgg caucccgacc cggacgaaca ucggcuggau ggucagccug cgcuaccgga     1620

acaagcacau cugcgggggc ucccucauca aggagagcug ggugcugacc gcccgccagu     1680

gcuuccccuc ccgggaccug aaggacuacg aggccuggcu cgggauccac gacgugcacg     1740

gccgcgggga cgagaagugc aagcaggucc ugaacgugag ccagcuggug uacggccccg     1800

agggcuccga ccucguccug augaagcugg cgcggcccgc cgugcucgac gacuucguga     1860

gcaccaucga ccugccgaac uacgggugca ccauccccga gaagacgucc ugcagcgucu     1920

acggcugggg guacaccggc cugaucaacu acgacggccu ccugcgcgug gcccaccugu     1980

acaucauggg gaacgagaag ugcucccagc accaccgggg caaggucacc cucaacgaga     2040

gcgagaucug cgccggggcc gagaagaucg gcuccgggcc cugcgagggc gacuacggcg     2100

ggccccuggu gugcgagcag cacaagaugc gcauggugcu gggcgucauc gugccggggc     2160

ggggcugcgc gauccccaac cgccccggga ucuucgugcg ggucgccuac uacgccaagu     2220

ggauccacaa gaucauccuc accuacaagg ugccccagag cugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  3948
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt1)

<400>  3948
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggccg cggccaucgg caucgaccug gggaccaccu      120

acagcugcgu gggcguguuc cagcacggga agguggagau caucgccaac gaccagggca      180

accgcacgac ccccuccuac guggccuuca ccgacaccga gcggcucauc ggggacgccg      240

cgaagaacca ggucgcccug aacccgcaga acacgguguu cgacgccaag cgccugaucg      300

gccggaaguu cggcgacccc gugguccaga gcgacaugaa gcacuggccc uuccagguga      360

ucaacgacgg ggacaagccc aaggugcagg ucuccuacaa gggcgagacc aaggccuucu      420

acccggagga gaucagcucc auggugcuca ccaagaugaa ggagaucgcg gaggccuacc      480

ugggguaccc cgugaccaac gccgucauca cggugcccgc cuacuucaac gacagccagc      540

gccaggccac caaggacgcg ggcgugaucg ccgggcugaa cguccuccgg aucaucaacg      600

agcccaccgc cgccgccauc gcguacggcc uggaccgcac cggcaagggg gagcggaacg      660

ugcugaucuu cgaccucggc gggggcacgu ucgacguguc cauccugacc aucgacgacg      720

gcaucuucga ggucaaggcc accgccgggg acacccaccu gggcggggag gacuucgaca      780

accgccucgu gaaccacuuc guggaggagu ucaagcggaa gcacaagaag gacaucagcc      840

agaacaagcg cgccguccgg cgccugcgga cggccugcga gcgcgcgaag cggacccugu      900

ccagcuccac ccaggccagc cucgagaucg acucccuguu cgagggcauc gacuucuaca      960

ccagcaucac gcgcgcccgg uucgaggagc ugugcuccga ccucuuccgc agcacccugg     1020

agccggugga gaaggcccug cgggacgcca agcucgacaa ggcgcagauc cacgaccugg     1080

ugcuggucgg gggcuccacc cgcaucccca aggugcagaa gcuccugcag gacuucuuca     1140

acggccggga ccugaacaag agcaucaacc ccgacgaggc cgucgccuac ggggccgcgg     1200

ugcaggccgc cauccucaug ggcgacaagu ccgagaacgu gcaggaccug cugcuccugg     1260

acgucgcgcc ccugagccuc gggcuggaga ccgccggcgg ggugaugacg gcccugauca     1320

agcgcaacag caccaucccg accaagcaga cccagaucuu cacgaccuac uccgacaacc     1380

agcccggcgu gcucauccag gucuacgagg gcgagcgcgc caugaccaag gacaacaacc     1440

ugcuggggcg guucgagcuc agcggcaucc cgcccgcgcc ccgcggggug ccccagaucg     1500

aggugaccuu cgacaucgac gccaacggca uccugaacgu cacggccacc gacaagucca     1560

ccgggaaggc caacaagauc accaucacga acgacaaggg ccggcugagc aaggaggaga     1620

ucgagcgcau ggugcaggag gccgagaagu acaaggccga ggacgaggug cagcgggagc     1680

gcgucuccgc caagaacgcc cucgagagcu acgcguucaa caugaagucc gccguggagg     1740

acgagggccu gaaggggaag aucagcgagg ccgacaagaa gaaggugcug gacaagugcc     1800

aggaggucau cuccuggcuc gacgccaaca cccuggcgga gaaggacgag uucgagcaca     1860

agcggaagga gcuggagcag gucugcaacc ccaucaucag cggccucuac cagggggccg     1920

gcggccccgg gccgggcggg uucggcgccc aggggcccaa gggcggcucc gggagcggcc     1980

ccaccaucga ggagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  3949
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt1)

<400>  3949
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggccg cggccaucgg caucgaccug gggaccaccu      120

acagcugcgu gggcguguuc cagcacggga agguggagau caucgccaac gaccagggca      180

accgcacgac ccccuccuac guggccuuca ccgacaccga gcggcucauc ggggacgccg      240

cgaagaacca ggucgcccug aacccgcaga acacgguguu cgacgccaag cgccugaucg      300

gccggaaguu cggcgacccc gugguccaga gcgacaugaa gcacuggccc uuccagguga      360

ucaacgacgg ggacaagccc aaggugcagg ucuccuacaa gggcgagacc aaggccuucu      420

acccggagga gaucagcucc auggugcuca ccaagaugaa ggagaucgcg gaggccuacc      480

ugggguaccc cgugaccaac gccgucauca cggugcccgc cuacuucaac gacagccagc      540

gccaggccac caaggacgcg ggcgugaucg ccgggcugaa cguccuccgg aucaucaacg      600

agcccaccgc cgccgccauc gcguacggcc uggaccgcac cggcaagggg gagcggaacg      660

ugcugaucuu cgaccucggc gggggcacgu ucgacguguc cauccugacc aucgacgacg      720

gcaucuucga ggucaaggcc accgccgggg acacccaccu gggcggggag gacuucgaca      780

accgccucgu gaaccacuuc guggaggagu ucaagcggaa gcacaagaag gacaucagcc      840

agaacaagcg cgccguccgg cgccugcgga cggccugcga gcgcgcgaag cggacccugu      900

ccagcuccac ccaggccagc cucgagaucg acucccuguu cgagggcauc gacuucuaca      960

ccagcaucac gcgcgcccgg uucgaggagc ugugcuccga ccucuuccgc agcacccugg     1020

agccggugga gaaggcccug cgggacgcca agcucgacaa ggcgcagauc cacgaccugg     1080

ugcuggucgg gggcuccacc cgcaucccca aggugcagaa gcuccugcag gacuucuuca     1140

acggccggga ccugaacaag agcaucaacc ccgacgaggc cgucgccuac ggggccgcgg     1200

ugcaggccgc cauccucaug ggcgacaagu ccgagaacgu gcaggaccug cugcuccugg     1260

acgucgcgcc ccugagccuc gggcuggaga ccgccggcgg ggugaugacg gcccugauca     1320

agcgcaacag caccaucccg accaagcaga cccagaucuu cacgaccuac uccgacaacc     1380

agcccggcgu gcucauccag gucuacgagg gcgagcgcgc caugaccaag gacaacaacc     1440

ugcuggggcg guucgagcuc agcggcaucc cgcccgcgcc ccgcggggug ccccagaucg     1500

aggugaccuu cgacaucgac gccaacggca uccugaacgu cacggccacc gacaagucca     1560

ccgggaaggc caacaagauc accaucacga acgacaaggg ccggcugagc aaggaggaga     1620

ucgagcgcau ggugcaggag gccgagaagu acaaggccga ggacgaggug cagcgggagc     1680

gcgucuccgc caagaacgcc cucgagagcu acgcguucaa caugaagucc gccguggagg     1740

acgagggccu gaaggggaag aucagcgagg ccgacaagaa gaaggugcug gacaagugcc     1800

aggaggucau cuccuggcuc gacgccaaca cccuggcgga gaaggacgag uucgagcaca     1860

agcggaagga gcuggagcag gucugcaacc ccaucaucag cggccucuac cagggggccg     1920

gcggccccgg gccgggcggg uucggcgccc aggggcccaa gggcggcucc gggagcggcc     1980

ccaccaucga ggagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  3950
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt1)

<400>  3950
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaccgcca agggcaucgc gaucgggauc gaccugggca      120

ccacguacag cugcgugggg gucuuccagc acggcaaggu ggagaucauc gccaacgacc      180

aggggaaccg caccaccccc uccuacgugg ccuucaccga cacggagcgg cucaucggcg      240

acgccgccaa gaaccagguc gcgaugaacc cgcagaacac cguguucgac gccaagcgcc      300

ugaucggccg gaaguucaac gaccccgugg uccaggccga caugaagcug uggcccuucc      360

aggugaucaa cgagggcggg aagcccaagg ugcucgucag cuacaagggg gagaacaagg      420

ccuucuaccc ggaggagauc uccagcaugg ugcugaccaa gcugaaggag accgcggagg      480

ccuuccucgg ccaccccgug acgaacgccg ucaucaccgu gcccgccuac uucaacgacu      540

cccagcgcca ggccaccaag gacgcggggg ugaucgccgg ccugaacguc cugcggauca      600

ucaacgagcc caccgccgcc gccaucgcgu acggccucga caagggcggg cagggggagc      660

gccacgugcu gaucuucgac cugggcggcg ggacguucga cgugagcauc cucaccaucg      720

acgacggcau cuucgagguc aaggccaccg ccggggacac ccaccugggc ggggaggacu      780

ucgacaaccg gcuggugucc cacuucgugg aggaguucaa gcgcaagcac aagaaggaca      840

ucagccagaa caagcgggcc guccgccggc uccgcacggc cugcgagcgg gcgaagcgca      900

cccuguccag cuccacccag gccaaccugg agaucgacag ccucuacgag ggcaucgacu      960

ucuacaccuc caucacgcgg gcccgcuucg aggagcugug cgccgaccug uuccggggca     1020

cccucgagcc gguggagaag gcccugcgcg acgcgaagau ggacaaggcc aagauccacg     1080

acaucgugcu ggucgggggc agcacccgga uccccaaggu gcagcgccuc cugcaggacu     1140

acuucaacgg gcgggaccug aacaagucca ucaaccccga cgaggccguc gccuacggcg     1200

cggccgugca ggccgccauc cucauggggg acaagagcga gaaggugcag gaccugcugc     1260

uccuggacgu cgcgccccug ucccucggcc uggagaccgc cggcggggug augacggccc     1320

ugaucaagcg caacagcacc aucccgacca agcagaccca gaucuucacg accuacuccg     1380

acaaccagcc cggcgugcuc auccaggucu acgaggggga gcgcgccaug accaaggaca     1440

acaaccugcu gggccgguuc gaccucaccg ggaucccgcc cgcgccccgc ggcgugcccc     1500

agaucgaggu gacguucgac aucgacgcca acggcauccu gaacgucacc gccaccgaca     1560

agagcaccgg gaaggugaac aagaucacga ucaccaacga caagggccgg cugagcaagg     1620

aggagaucga gcgcauggug cucgacgccg agaaguacaa ggccgaggac gagguccagc     1680

gggagaagau cgccgccaag aacgcgcugg aguccuacgc cuucaacaug aaguccgugg     1740

ugagcgacga ggggcugaag ggcaagauca gcgaguccga caagaacaag auccucgaca     1800

agugcaacga gcugcugagc uggcucgagg ucaaccagcu ggccgagaag gacgaguucg     1860

accacaagcg caaggagcug gagcagaugu gcaaccccau caucaccaag cuguaccagg     1920

gcgggugcac cggccccgcc ugcgggaccg gcuacgugcc ggggcggccc gcgacgggcc     1980

ccaccaucga ggagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  3951
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt1)

<400>  3951
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgcccgcg gccccgccau cgggaucgac cugggcacca      120

ccuacuccug cguggggguc uuccagcacg gcaaggugga gaucaucgcg aacgaccagg      180

ggaaccggac gaccccgagc uacguggccu ucaccgacac cgagcgccuc aucggcgacg      240

ccgccaagaa ccaggucgcc augaacccca cgaacaccau cuucgacgcg aagcggcuga      300

ucggccgcaa guucgaggac gccaccgugc aguccgacau gaagcacugg cccuuccggg      360

uggucagcga gggcgggaag cccaaggucc agguggagua caagggggag accaagacgu      420

ucuucccgga ggagaucucc agcauggugc ugaccaagau gaaggagauc gccgaggccu      480

accucggcgg gaaggugcac uccgcgguga ucaccguccc cgccuacuuc aacgacagcc      540

agcgccaggc caccaaggac gccggcacga ucaccggccu gaacgugcug cggaucauca      600

acgagcccac cgccgcggcc aucgccuacg ggcucgacaa gaagggcugc gccgggggcg      660

agaagaacgu gcugaucuuc gaccugggcg ggggcaccuu cgacgucucc auccucacga      720

ucgaggacgg gaucuucgag gucaagagca ccgccggcga cacccaccuc gggggcgagg      780

acuucgacaa ccgcauggug ucccaccugg cggaggaguu caagcggaag cacaagaagg      840

acaucggccc caacaagcgc gccgugcggc gccugcggac cgccugcgag cgcgccaagc      900

ggacgcugag cuccagcacc caggccucca ucgagaucga cagccuguac gagggggugg      960

acuucuacac cuccaucacc cgcgcgcggu ucgaggagcu caacgccgac cuguuccgcg     1020

gcacgcugga gccgguggag aaggcccucc gggacgccaa gcuggacaag gggcagaucc     1080

aggagaucgu ccuggugggc gggagcaccc gcauccccaa gauccagaag cuccugcagg     1140

acuucuucaa cggcaaggag cugaacaagu ccaucaaccc cgacgaggcc guggcguacg     1200

gcgccgccgu ccaggccgcg auccucaucg gggacaagag cgagaacgug caggaccugc     1260

ugcuccugga cgucacgccc cugagccucg gcaucgagac cgccgggggc gugaugaccc     1320

cgcugaucaa gcggaacacc accaucccca ccaagcagac gcagaccuuc accaccuacu     1380

ccgacaacca gagcuccgug cugguccagg uguacgaggg ggagcgcgcc augacgaagg     1440

acaacaaccu ccugggcaag uucgaccuga ccggcauccc gcccgcgccc cgcggggugc     1500

cccagaucga ggucaccuuc gacaucgacg ccaacggcau ccucaacgug accgccgccg     1560

acaagagcac cgggaaggag aacaagauca cgaucaccaa cgacaagggc cggcugucca     1620

aggacgacau cgaccgcaug gugcaggagg ccgagcggua caagagcgag gacgaggcca     1680

accgcgaccg ggucgccgcg aagaacgccc uggaguccua caccuacaac aucaagcaga     1740

ccguggagga cgagaagcuc cgcggcaaga ucagcgagca ggacaagaac aagauccugg     1800

acaagugcca ggaggugauc aacuggcugg accggaacca gauggccgag aaggacgagu     1860

acgagcacaa gcagaaggag cucgagcgcg ucugcaaccc caucaucucc aagcuguacc     1920

agggcgggcc cgggggcggg agcggcggcg ggggcuccgg ggccagcggc gggccgacga     1980

ucgaggaggu ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  3952
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt1)

<400>  3952
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccag uccugcuacg      120

uggccguggc ccgcgcgggc gggaucgaga ccaucgccaa cgaguacagc gaccggugca      180

cccccgccug caucuccuuc ggcccgaaga accgcagcau cggggccgcc gcgaaguccc      240

aggucaucag caacgccaag aacacggugc agggcuucaa gcgguuccac ggccgcgccu      300

ucuccgaccc cuucguggag gccgagaagu ccaaccucgc guacgacauc guccagcugc      360

ccaccgggcu gaccggcauc aaggugaccu acauggagga ggagcggaac uucacgaccg      420

agcaggucac cgccaugcuc cugagcaagc ugaaggagac cgccgagagc gugcucaaga      480

agcccguggu ggacugcguc guguccgugc cgugcuucua cacggacgcc gagcgccgga      540

gcgucaugga cgccacccag aucgcggggc ugaacugccu gcgccucaug aacgagacca      600

ccgccguggc ccuggccuac ggcaucuaca agcaggaccu gcccgcccuc gaggagaagc      660

cccggaacgu ggucuucgug gacauggggc acuccgcgua ccaggugagc gucugcgccu      720

ucaaccgcgg caagcugaag gugcuggcca cggccuucga caccacccuc ggcgggcgga      780

aguucgacga ggugcugguc aaccacuucu gcgaggaguu cggcaagaag uacaagcugg      840

acaucaaguc caagauccgc gcccuccugc ggcugagcca ggagugcgag aagcucaaga      900

agcugauguc cgcgaacgcc agcgaccugc cccucuccau cgagugcuuc augaacgacg      960

uggacgucag cgggaccaug aaccgcggca aguuccugga gaugugcaac gaccugcucg     1020

cccgggugga gccgccccug cgcagcgugc uggagcagac gaagcucaag aaggaggaca     1080

ucuacgccgu cgagaucgug ggcggggcca cccggauccc cgcggugaag gagaagaucu     1140

ccaaguucuu cggcaaggag cugagcacca cccugaacgc cgacgaggcc gucacgcgcg     1200

ggugcgcccu ccagugcgcg auccuguccc ccgccuucaa ggugcgggag uucagcauca     1260

ccgacguggu cccguacccc aucucccugc gcuggaacag ccccgccgag gagggcucca     1320

gcgacugcga gguguucucc aagaaccacg ccgcccccuu cagcaaggug cucaccuucu     1380

accggaagga gccguucacc cuggaggcgu acuacuccag cccccaggac cugcccuacc     1440

ccgacccggc caucgcccag uucuccgucc agaaggugac gccccagagc gacgggucca     1500

gcuccaaggu gaaggucaag gugcgcguga acguccacgg caucuucagc guguccagcg     1560

ccagccucgu ggagguccac aaguccgagg agaacgagga gcccauggag accgaccaga     1620

acgccaagga ggaggagaag augcaggucg accaggagga gccccacgug gaggagcagc     1680

agcagcagac cccggcggag aacaaggccg agagcgagga gauggagacc ucccaggccg     1740

gcagcaagga caagaagaug gaccagccgc cccaggccaa gaaggccaag gugaagacgu     1800

ccaccgugga ccugcccauc gagaaccagc ugcucuggca gaucgaccgc gagaugcuga     1860

accuguacau cgagaacgag gggaagauga ucaugcagga caagcucgag aaggagcgga     1920

acgacgcgaa gaacgccgug gaggaguacg ucuacgagau gcgcgacaag cugagcggcg     1980

aguacgagaa guucgugucc gaggacgacc ggaacagcuu cacccugaag cucgaggaca     2040

ccgagaacug gcuguacgag gacggggagg accagcccaa gcaggucuac guggacaagc     2100

uggccgagcu gaagaaccuc ggccagccca ucaagauccg cuuccaggag uccgaggagc     2160

ggcccaagcu guucgaggag cuggggaagc agauccagca guacaugaag aucaucagcu     2220

ccuucaagaa caaggaggac caguacgacc accucgacgc cgcggacaug acgaaggugg     2280

agaaguccac caacgaggcc auggagugga ugaacaacaa gcugaaccug cagaacaagc     2340

agagccucac cauggacccg guggucaaga gcaaggagau cgaggccaag aucaaggagc     2400

ugaccuccac gugcagcccc aucaucucca agcccaagcc caagguggag ccgcccaagg     2460

aggagcagaa gaacgccgag cagaacggcc ccguggacgg ccagggggac aaccccggcc     2520

cgcaggccgc ggagcagggg accgacaccg ccguccccag cgacagcgac aagaagcugc     2580

ccgagaugga caucgacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  3953
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt1)

<400>  3953
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccuc aacugcuaca      120

ucgccguggc ccgcuccggc gggaucgaga ccaucgcgaa cgaguacagc gaccggugca      180

cccccgccug caucucccug ggcagccgca cgcgggccau cgggaacgcc gccaaguccc      240

agaucgugac caacguccgc aacaccaucc acggcuucaa gaagcugcac ggccggagcu      300

ucgacgaccc gaucgugcag accgagcgca uccggcuccc cuacgagcug cagaagaugc      360

ccaacggguc cgcgggcgug aagguccgcu accuggagga ggagcggccc uucgccaucg      420

agcaggucac ggggaugcuc cuggccaagc ugaaggagac cagcgagaac gcccucaaga      480

agccgguggc ggacugcgug aucuccaucc ccagcuucuu caccgacgcc gagcgccggu      540

ccgugauggc cgccgcccag guggcgggcc ugaacugccu gcgccucaug aacgagacca      600

cggccgucgc ccuggccuac gggaucuaca agcaggaccu gccgccccuc gacgagaagc      660

cccggaacgu gguguucauc gacaugggcc acagcgccua ccagguccug gugugcgcgu      720

ucaacaaggg caagcugaag gugcucgcca ccaccuucga ccccuaccuc gggggccgca      780

acuucgacga ggcccugguc gacuacuucu gcgacgaguu caagaccaag uacaagauca      840

acgugaagga gaacucccgg gcccugcugc gccuguacca ggagugcgag aagcucaaga      900

agcugaugag cgccaacgcg uccgaccugc cccucaacau cgagugcuuc augaacgacc      960

uggacgugag cuccaagaug aaccgggccc aguucgagca gcugugcgcc agccuccugg     1020

cccgcgucga gcccccgcug aaggccguga uggagcaggc gaaccuccag cgggaggaca     1080

ucuccagcau cgagaucguc gggggcgcca cgcgcauccc cgccgugaag gagcagauca     1140

ccaaguucuu ccugaaggac aucagcacca cccugaacgc cgacgaggcg guggcccggg     1200

gcugcgcccu ccagugcgcc auccuguccc ccgccuucaa gguccgcgag uucagcauca     1260

cggaccuggu gcccuacucc aucacccucc gcuggaagac cagcuucgag gacggguccg     1320

gcgagugcga gguguucugc aagaaccacc cggcgcccuu cagcaagguc aucaccuucc     1380

acaagaagga gcccuucgag cuggaggccu ucuacacgaa ccugcacgag gugcccuacc     1440

cggacgcccg gaucgggucc uucaccaucc agaacguguu cccccagagc gacggcgacu     1500

ccagcaaggu caaggugaag gugcgcguca acauccacgg gaucuucucc guggccagcg     1560

ccuccgugau cgagaagcag aaccucgagg gcgaccacag cgacgcgccc auggagaccg     1620

agaccuccuu caagaacgag aacaaggaca acauggacaa gaugcagguc gaccaggagg     1680

agggccacca gaagugccac gccgagcaca cgcccgagga ggagaucgac cacaccgggg     1740

ccaagaccaa gagcgccgug uccgacaagc aggaccggcu gaaccagacc cugaagaagg     1800

gcaaggucaa gagcaucgac cucccgaucc aguccagccu gugccgccag cuggggcagg     1860

accuccugaa cagcuacauc gagaacgagg gcaagaugau caugcaggac aagcuggaga     1920

aggagcggaa cgacgccaag aacgcggugg aggaguacgu guacgacuuc cgcgaccggc     1980

uggggacggu guacgagaag uucaucaccc ccgaggaccu cuccaagcug agcgccgucc     2040

uggaggacac cgagaacugg cucuacgagg acggcgagga ccagcccaag caggucuacg     2100

uggacaagcu gcaggagcug aagaaguacg gccagcccau ccagaugaag uacauggagc     2160

acgaggagcg cccgaaggcc cucaacgacc uggggaagaa gauccagcug gugaugaagg     2220

ugaucgaggc cuaccggaac aaggacgagc gcuacgacca ccucgacccc accgagaugg     2280

agaaggugga gaagugcauc uccgacgcga ugagcuggcu gaacuccaag augaacgccc     2340

agaacaagcu gagccucacg caggaccccg ucgugaaggu guccgagauc gucgccaaga     2400

gcaaggagcu ggacaacuuc ugcaacccga ucaucuacaa gcccaagccc aaggccgagg     2460

ugcccgagga caagccgaag gccaacuccg agcacaacgg ccccauggac gggcagagcg     2520

gcaccgagac caaguccgac agcaccaagg acuccagcca gcacacgaag uccagcgggg     2580

agauggaggu ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  3954
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt1)

<400>  3954
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugagcc ucguggccgc caugcugcug cuccuguccg      120

cggcccgcgc cgaggaggag gacaagaagg aggacgucgg caccguggug gggaucgacc      180

ugggcaccac guacagcugc gucggggugu ucaagaacgg ccggguggag aucaucgcca      240

acgaccaggg gaaccgcauc acccccuccu acgucgccuu caccccggag ggcgagcggc      300

ucaucggcga cgcggccaag aaccagcuga ccagcaaccc cgagaacacg guguucgacg      360

ccaagcgccu gaucgggcgg accuggaacg accccuccgu gcagcaggac aucaaguucc      420

uccccuucaa ggucguggag aagaagacca agccguacau ccagguggac aucggcgggg      480

gccagaccaa gacguucgcc cccgaggaga ucagcgcgau gguccugacc aagaugaagg      540

agaccgccga ggccuaccug gggaagaagg ugacccacgc cguggucacg gugcccgccu      600

acuucaacga cgcgcagcgc caggccacca aggacgccgg caccaucgcc ggccucaacg      660

ugaugcggau caucaacgag cccaccgccg cggccaucgc cuacgggcug gacaagcgcg      720

agggcgagaa gaacauccug gucuucgacc ucgggggcgg cacguucgac gugucccugc      780

ugaccaucga caacggggug uucgaggucg uggccaccaa cggcgacacc caccucgggg      840

gcgaggacuu cgaccagcgg gugauggagc acuucaucaa gcuguacaag aagaagacgg      900

ggaaggacgu ccgcaaggac aaccgggccg ugcagaagcu gcgccgggag gucgagaagg      960

cgaagcgcgc ccucagcucc cagcaccagg cccggaucga gaucgagagc uucuacgagg     1020

gcgaggacuu cuccgagacc cugacccgcg ccaaguucga ggagcugaac auggaccucu     1080

uccggagcac caugaagccg gugcagaagg ugcuggagga cuccgaccug aagaaguccg     1140

acaucgacga gaucguccuc gugggcggga gcacgcgcau ccccaagauc cagcagcugg     1200

ugaaggaguu cuucaacggc aaggagccca gccgggggau caaccccgac gaggccgucg     1260

cguacggcgc cgccgugcag gccggggugc uguccggcga ccaggacacc ggcgaccucg     1320

uccugcugga cgugugcccg cucacccugg ggaucgagac cgugggcggg gucaugacga     1380

agcugauccc ccgcaacacc guggugccca ccaagaaguc ccagaucuuc agcaccgcga     1440

gcgacaacca gcccacgguc accaucaagg uguacgaggg cgagcggccg cucaccaagg     1500

acaaccaccu ccuggggacc uucgaccuga cgggcauccc gcccgcgccc cgcggcgugc     1560

cccagaucga ggucaccuuc gagaucgacg ugaacgggau ccugcgcgug accgccgagg     1620

acaagggcac cgggaacaag aacaagauca ccaucacgaa cgaccagaac cggcugaccc     1680

ccgaggagau cgagcgcaug gucaacgacg ccgagaaguu cgccgaggag gacaagaagc     1740

ucaaggagcg gaucgacacc cgcaacgagc uggagagcua cgccuacucc cugaagaacc     1800

agaucggcga caaggagaag cucggcggga agcugagcuc cgaggacaag gagaccaugg     1860

agaaggccgu ggaggagaag aucgaguggc uggagagcca ccaggacgcc gacaucgagg     1920

acuucaaggc caagaagaag gagcucgagg agaucgugca gcccaucauc uccaagcugu     1980

acggcagcgc cgggcccccg cccacgggcg aggaggacac cgcggagaag gacgagcugu     2040

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  3955
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt1)

<400>  3955
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggcgcccc gcgagcuggc cgugggcauc gaccucggga      120

ccaccuacag cugcgucggc guguuccagc aggggcgggu ggagauccug gccaacgacc      180

agggcaaccg cacgaccccg uccuacgucg ccuucaccga caccgagcgg cugguggggg      240

acgccgccaa gagccaggcc gcgcucaacc cccacaacac gguguucgac gccaagcgcc      300

ugaucggccg gaaguucgcc gacaccaccg uccaguccga caugaagcac uggcccuucc      360

gcguggugag cgagggcggg aagcccaagg uccgggugug cuaccgcggc gaggacaaga      420

ccuucuaccc ggaggagauc uccagcaugg ugcuguccaa gaugaaggag acggccgagg      480

cguaccucgg gcagcccguc aagcacgccg ugaucaccgu gcccgccuac uucaacgaca      540

gccagcggca ggccaccaag gacgccggcg cgaucgccgg gcugaacguc cugcgcauca      600

ucaacgagcc caccgccgcc gccaucgcgu acggccucga ccggcgcggc gccggggagc      660

ggaacgugcu gaucuucgac cugggcgggg gcacguucga cguguccguc cucagcaucg      720

acgccggcgu guucgaggug aaggccaccg ccggggacac ccaccugggc ggggaggacu      780

ucgacaaccg ccuggucaac cacuucaugg aggaguuccg gcgcaagcac ggcaaggacc      840

ucuccgggaa caagcgggcg cugcgccggc ugcgcaccgc cugcgagcgg gccaagcgca      900

cgcucagcuc cagcacccag gccacccugg agaucgacuc ccuguucgag ggcguggacu      960

ucuacaccag caucacgcgc gcccgguucg aggagcucug cuccgaccug uuccgcagca     1020

cccuggagcc gguggagaag gcgcuccggg acgccaagcu ggacaaggcc cagauccacg     1080

acgucgugcu ggucggcggg uccacccgca uccccaaggu gcagaagcuc cugcaggacu     1140

ucuucaacgg caaggagcug aacaagagca ucaaccccga cgaggccgug gcguacgggg     1200

ccgccgucca ggccgccgug cucaugggcg acaagugcga gaaggugcag gaccugcugc     1260

uccuggacgu cgcgccccug agccucgggc uggagaccgc cggcggcgug augacgaccc     1320

ugauccagcg gaacgccacc aucccgacca agcagacgca gaccuucacc accuacuccg     1380

acaaccagcc cgggguguuc auccaggucu acgagggcga gcgcgccaug acgaaggaca     1440

acaaccuccu ggggcgguuc gagcugagcg gcaucccgcc cgcgccccgc ggggugcccc     1500

agaucgaggu gaccuucgac aucgacgcca acggcauccu cuccgucacc gccaccgacc     1560

ggagcacggg caaggccaac aagaucacca ucaccaacga caaggggcgc cuguccaagg     1620

aggaggugga gcggauggug cacgaggccg agcaguacaa ggccgaggac gaggcgcagc     1680

gcgaccgggu cgccgccaag aacagccugg aggcccacgu guuccacgug aagggcuccc     1740

uccaggagga gagccugcgc gacaagaucc ccgaggagga ccggcgcaag augcaggaca     1800

agugccggga gguccuggcg uggcucgagc acaaccagcu ggccgagaag gaggaguacg     1860

agcaccagaa gcgcgagcug gagcagaucu gccggcccau cuucucccgc cuguacgggg     1920

gcccgggcgu gcccgggggc agcuccugcg ggacccaggc ccgccagggc gaccccagca     1980

ccgggcccau caucgaggag guggacugag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  3956
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt1)

<400>  3956
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggcgcccc gcgagcuggc cgugggcauc gaccucggga      120

ccaccuacag cugcgucggc guguuccagc aggggcgggu ggagauccug gccaacgacc      180

agggcaaccg cacgaccccg uccuacgucg ccuucaccga caccgagcgg cugguggggg      240

acgccgccaa gagccaggcc gcgcucaacc cccacaacac gguguucgac gccaagcgcc      300

ugaucggccg gaaguucgcc gacaccaccg uccaguccga caugaagcac uggcccuucc      360

agguggugag cgagggcggg aagcccaagg uccgcgugug cuaccggggc gaggacaaga      420

ccuucuaccc ggaggagauc uccagcaugg ugcuguccaa gaugaaggag acggccgagg      480

cguaccucgg gcagcccguc aagcacgccg ugaucaccgu gcccaccuac uucagcaacu      540

cccagcgcca ggccaccaag gacgccggcg ccaucgcggg gcugaagguc cugcccauca      600

ucaacgaggc cacggccgcc gccaucgcgu acggccucga ccggcgcggc gccgggaagc      660

ggaacgugcu gaucuucgac cugggcgggg gcaccuucga cgugagcguc cucuccaucg      720

acgccggcgu guucgaggug aaggccaccg ccggggacac ccaccugggc ggggaggacu      780

ucgacaaccg ccuggucaac cacuucaugg aggaguuccg gcgcaagcac ggcaaggacc      840

ucagcgggaa caagcgggcg cugcgccggc ugcgcacggc cugcgagcgg gccaagcgca      900

ccccguccag cuccacccag gccacccucg agaucgacag ccuguucgag ggcguggacu      960

ucuacaaguc caucacgcgg gcccgcuucg aggagcugug cagcgaccuc uuccgcucca     1020

cccuggagcc cguggagaag gcgcugcggg acgccaagcu cgacaaggcc cagauccacg     1080

acuucguccu gggcgggggc cugcacagcc acccccaggg ggccgaggug gcggccggcc     1140

uccugcagcg ccagggggcc gagcaggagc accagcccug aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  3957
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt1)

<400>  3957
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaagggcc ccgccguggg gaucgaccug ggcaccaccu      120

acuccugcgu cgggguguuc cagcacggca agguggagau caucgccaac gaccagggga      180

accgcacgac ccccagcuac gucgcguuca ccgacaccga gcggcucauc ggcgacgccg      240

ccaagaacca gguggccaug aaccccacga acaccguguu cgacgccaag cgccugaucg      300

gccggcgcuu cgacgacgcg gucgugcagu ccgacaugaa gcacuggccc uucauggugg      360

ucaacgacgc cgggcggccc aagguccagg uggaguacaa gggcgagacc aagagcuucu      420

acccggagga gguguccagc auggugcuga ccaagaugaa ggagaucgcc gaggccuacc      480

ucgggaagac ggugaccaac gcggucguga ccgugcccgc cuacuucaac gacucccagc      540

gccaggccac caaggacgcc ggcacgaucg ccgggcugaa cguccugcgg aucaucaacg      600

agcccaccgc ggccgccauc gccuacggcc ucgacaagaa ggugggcgcc gagcgcaacg      660

ugcugaucuu cgaccucggg ggcgggaccu ucgacgucag cauccugacc aucgaggacg      720

gcaucuucga ggugaagucc acggcgggcg acacccaccu cgggggcgag gacuucgaca      780

accggauggu gaaccacuuc aucgccgagu ucaagcgcaa gcacaagaag gacaucagcg      840

agaacaagcg ggccguccgc cggcugcgca ccgccugcga gcgggccaag cgcacccugu      900

ccagcuccac gcaggcgagc aucgagaucg acucccugua cgaggggauc gacuucuaca      960

ccagcaucac ccgggcccgc uucgaggagc ugaacgccga ccucuuccgg ggcacccugg     1020

accccgugga gaaggcccug cgcgacgcca agcucgacaa gucccagauc cacgacaucg     1080

uccuggucgg gggcagcacg cggaucccga agauccagaa gcugcuccag gacuucuuca     1140

acggcaagga gcugaacaag uccaucaacc ccgacgaggc gguggccuac ggggccgccg     1200

ugcaggcggc cauccugagc ggcgacaaga gcgagaacgu gcaggaccuc cugcugcucg     1260

acgugacgcc ccugucccug gggaucgaga ccgccggcgg ggucaugacc gugcucauca     1320

agcgcaacac caccaucccc accaagcaga cccagacguu caccaccuac agcgacaacc     1380

agccgggcgu gcugauccag gucuacgagg gcgagcgcgc caugaccaag gacaacaacc     1440

ugcucgggaa guucgagcug acgggcaucc cgcccgcgcc ccgcggggug ccccagaucg     1500

aggugaccuu cgacaucgac gccaacggca uccugaacgu cuccgccgug gacaagagca     1560

ccgggaagga gaacaagauc accaucacca acgacaaggg ccggcucucc aaggaggaca     1620

ucgagcggau ggugcaggag gccgagaagu acaaggccga ggacgagaag cagcgcgaca     1680

aggucagcuc caagaacagc cuggaguccu acgccuucaa caugaaggcg acgguggagg     1740

acgagaagcu gcagggcaag aucaacgacg aggacaagca gaagauccuc gacaagugca     1800

acgagaucau caacuggcug gacaagaacc agaccgccga gaaggaggag uucgagcacc     1860

agcagaagga gcuggagaag gugugcaacc ccaucaucac caagcucuac cagagcgccg     1920

ggggcaugcc cgggggcaug cccggcgggu ucccgggcgg gggcgccccg cccuccgggg     1980

gcgccagcuc cggccccacc aucgaggagg ucgacugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  3958
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt1)

<400>  3958
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucagcgccu cccgcgccgc ggccgcccgg cuggugggcg      120

ccgccgcgag ccgcgggccc accgccgccc ggcaccagga cuccuggaac ggccucagcc      180

acgaggccuu ccgccugguc ucccggcgcg acuacgcgag cgaggccauc aagggggccg      240

uggugggcau cgaccugggg accacgaacu ccugcgucgc cgugauggag ggcaagcagg      300

ccaaggugcu cgagaacgcg gagggcgccc ggaccacccc gagcgucgug gccuucaccg      360

ccgacgggga gcgccuggug ggcaugcccg ccaagcggca ggcggucacg aaccccaaca      420

acaccuucua cgccaccaag cgccugaucg ggcggcgcua cgacgacccc gaggugcaga      480

aggacaucaa gaacgugccg uucaagaucg uccgggccuc caacggcgac gccugggugg      540

aggcccacgg gaagcucuac agccccuccc agaucggcgc guucgugcug augaagauga      600

aggagaccgc cgagaacuac cugggccaca cggccaagaa cgccgucauc accgugcccg      660

ccuacuucaa cgacagccag cgccaggcga ccaaggacgc cgggcagauc uccggccuca      720

acgugcugcg ggucaucaac gagcccaccg ccgccgcgcu ggccuacggg cucgacaaga      780

gcgaggacaa ggugaucgcc guguacgacc ugggcggcgg gacguucgac aucuccaucc      840

uggagaucca gaagggcguc uucgagguca agagcaccaa cggggacacc uuccucggcg      900

gggaggacuu cgaccaggcc cugcugcgcc acaucgugaa ggaguucaag cgggagaccg      960

gcguggaccu cacgaaggac aacauggccc ugcagcgcgu gcgggaggcg gccgagaagg     1020

ccaagugcga gcuguccagc uccguccaga ccgacaucaa ccucccguac cugaccaugg     1080

acagcagcgg ccccaagcac cugaacauga agcucacccg cgcccaguuc gaggggaucg     1140

ugacggaccu gauccggcgc accaucgccc ccugccagaa ggcgaugcag gacgccgagg     1200

uguccaagag cgacaucggc gaggucaucc uggucggggg caugacccgc augcccaagg     1260

ugcagcagac cgugcaggac cucuucgggc gggccccguc caaggccgug aaccccgacg     1320

aggccguggc gaucggcgcc gccauccagg gcgggguccu ggccggcgac gugacggacg     1380

ugcugcuccu ggacgucacg ccccugagcc ucgggaucga gacccugggc gggguguuca     1440

ccaagcugau caaccgcaac accaccaucc ccaccaagaa gucccaggug uucagcaccg     1500

cggccgacgg ccagacgcag gucgagauca aggugugcca gggcgagcgg gagauggccg     1560

gggacaacaa gcuccugggc caguucaccc ugaucgggau cccgcccgcg ccccgcggcg     1620

ugccccagau cgaggucacc uucgacaucg acgccaacgg caucgugcac guguccgcca     1680

aggacaaggg gaccggccgg gagcagcaga ucgucaucca gagcuccggg ggccucagca     1740

aggacgacau cgagaacaug gugaagaacg ccgagaagua cgccgaggag gaccgccgga     1800

agaaggagcg cguggaggcc gucaacaugg ccgaggggau cauccacgac acggagacca     1860

agauggagga guucaaggac cagcugccgg cggacgagug caacaagcug aaggaggaga     1920

ucuccaagau gcgggagcuc cuggcccgca aggacagcga gaccggcgag aacauccggc     1980

aggccgccuc cagccugcag caggccuccc ucaagcuguu cgagauggcg uacaagaaga     2040

uggccagcga gcgcgagggc uccgggagcu ccggcaccgg ggagcagaag gaggaccaga     2100

aggaggagaa gcagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  3959
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt1)

<400>  3959
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg aggccggcgg gagcgacggc ccccgcgaga      120

ccgcgccgac cuccgccuac agcucccccg cccggagccu gggggacacg ggcaucacgc      180

cccucucccc cagccacauc gugaacgaca ccgacuccaa cgucagcgag cagcaguccu      240

uccugguggu ggucgccgug gacuucggga ccaccagcuc cggcuacgcc uacagcuuca      300

ccaaggagcc ggagugcauc cacgugaugc gccgguggga gggcggggac cccggcgucu      360

ccaaccagaa gacccccacc acgauccugc ucacccccga gcgcaaguuc cacagcuucg      420

gguacgcggc ccgggacuuc uaccacgacc uggacccgaa cgaggccaag caguggcugu      480

accucgagaa guucaagaug aagcugcaca ccaccggcga ccugacgaug gacaccgacc      540

ucaccgccgc gaacgggaag aaggugaagg cccuggagau cuucgccuac gcccugcagu      600

acuucaagga gcaggcccuc aaggagcugu ccgaccaggc gggcagcgag uucgagaacu      660

ccgacgugcg cugggucauc accgugcccg ccaucuggaa gcagcccgcc aagcaguuca      720

ugcggcaggc cgccuaccag gcgggccugg ccagccccga gaacuccgag cagcucauca      780

ucgcccugga gccggaggcc gccagcaucu acugccgcaa gcugcggcuc caccagauga      840

ucgagcugag cuccaaggcg gccgugaacg gguacagcgg cuccgacacg gucggggccg      900

gcuucaccca ggccaaggag cacauccgcc ggaaccgcca gagccggacc uuccuggugg      960

agaacgugau cggcgagauc ugguccgagc ucgaggaggg ggacaaguac gucguggugg     1020

acagcggcgg gggcaccguc gaccugacgg ugcaccagau ccgccugccc gaggggcacc     1080

ucaaggagcu guacaaggcc accggcggcc ccuacggguc ccugggcgug gacuacgagu     1140

ucgagaagcu ccuguacaag aucuucgggg aggacuucau cgagcaguuc aagaucaagc     1200

ggcccgcggc cugggucgac cugaugaucg ccuucgagag ccgcaagcgg gccgcggccc     1260

cggaccgcac caacccccuc aacaucaccc ugcccuucuc cuucaucgac uacuacaaga     1320

aguuccgggg ccacagcgug gagcacgccc ugcgcaaguc caacguggac uucgucaagu     1380

ggagcuccca ggggaugcuc cggaugagcc ccgacgccau gaacgcccug uucaagccga     1440

cgaucgacuc caucaucgag caccuccgcg accuguucca gaagcccgag gugagcaccg     1500

ucaaguuccu guuccuggug ggcggcuucg cggaggcgcc ccuccugcag caggccgugc     1560

aggccgccuu cggggaccag ugccgcauca ucauccccca ggacgucggc cugaccaucc     1620

ucaagggggc cgugcuguuc ggccuggacc cggccgugau caagguccgg cgcagccccc     1680

ucaccuacgg ggugggcgug cugaaccggu acgucgaggg caagcacccg cccgagaagc     1740

ugcucgugaa ggacgggacg cgcuggugca ccgacguguu cgacaaguuc aucuccgccg     1800

accaguccgu cgcccugggc gagcugguga agcggagcua cacccccgcc aagcccagcc     1860

agcuggugau cgucaucaac aucuacucca gcgagcacga caacgugucc uucaucaccg     1920

accccggggu gaagaagugc ggcacgcucc gccuggaccu gaccggcacc agcgggaccg     1980

cggucccggc ccggcgcgag auccagacgc ucaugcaguu cggcgacacc gagaucaagg     2040

ccaccgccau cgacaucgcg accuccaaga gcgugaaggu ggggaucgac uuccugaacu     2100

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  3960
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt1)

<400>  3960
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuggccgugc ccgagauggg ccuccagggg cuguacaucg      120

gcagcucccc cgagcgcagc cccguccccu ccccgcccgg gagcccccgg acccaggagu      180

ccugcggcau cgccccgcug acccccagcc agucccccaa gcccgaggug cgcgcgcccc      240

agcaggccag cuucuccgug gucguggcca ucgacuucgg gacgaccagc uccggcuacg      300

ccuucagcuu cgccuccgac cccgaggcga uccacaugau gcggaagugg gagggcgggg      360

acccgggcgu ggcccaccag aagaccccga ccugccuccu gcugacgccc gagggggccu      420

uccacagcuu cggcuacacc gcccgcgacu acuaccacga ccucgacccc gaggaggcgc      480

gggacuggcu guacuucgag aaguucaaga ugaagaucca cuccgccacc gaccugaccc      540

ucaagacgca gcuggaggcc gucaacggga agaccaugcc cgcccuggag guguucgccc      600

acgcgcuccg cuucuuccgg gagcacgccc ugcaggagcu gcgcgagcag agccccuccc      660

uccccgagaa ggacaccgug cggugggucc ugaccgugcc cgccaucugg aagcagccgg      720

ccaagcaguu caugcgcgag gccgcguacc uggccggccu cgugagccgg gagaacgccg      780

agcagcugcu gaucgcccuc gagcccgagg ccgcguccgu cuacugccgc aagcugcggc      840

ugcaccagcu ccuggaccug agcggccgcg cccccggggg cgggcggcuc ggcgagcgcc      900

ggagcaucga cuccagcuuc cgccaggccc gggagcagcu gcgccggucc cgccacagcc      960

gcacguuccu gguggagucc ggcguggggg agcucugggc cgagaugcag gccggcgacc     1020

gguacgucgu ggcggacugc gggggcggga ccguggaccu gaccguccac cagcuggagc     1080

agccccacgg cacccucaag gagcuguaca aggccagcgg cgggccguac ggcgccgugg     1140

ggguggaccu ggccuucgag cagcuccugu gccgcaucuu cggcgaggac uucaucgcga     1200

cguucaagcg gcagcgcccc gccgccuggg ucgaccugac caucgccuuc gaggcccgga     1260

agcgcaccgc ggggccccac cgggccggcg cccucaacau cucccugccc uucagcuuca     1320

ucgacuucua ccgcaagcag cggggccaca acguggagac cgcccugcgc cgguccagcg     1380

ugaacuucgu caaguggucc agccagggga ugcuccgcau guccugcgag gccaugaacg     1440

agcuguucca gccgacggug agcggcauca uccagcacau cgaggcgcug cucgcccggc     1500

ccgaggucca gggggugaag cugcuguucc ucgugggcgg guucgccgag uccgccgucc     1560

ugcagcacgc cgugcaggcg gcccugggcg cccgcggccu gcgggugguc gugccccacg     1620

acguggggcu caccauccug aagggcgccg uccuguucgg gcaggcgccg ggcguggugc     1680

gcguccggcg cagcccccuc accuacggcg ugggggugcu gaaccgguuc guccccggcc     1740

gccacccgcc cgagaagcug cucgugcgcg acgggcggcg cuggugcacc gacguguucg     1800

agcgguucgu cgccgccgag caguccgugg cccugggcga ggaggugcgc cggagcuacu     1860

gccccgcccg ccccgggcag cggcgcgucc ugaucaaccu cuacugcugc gcggccgagg     1920

acgcccgguu caucacggac cccggcgugc gcaagugcgg cgcccugucc cuggagcucg     1980

agccggccga cugcgggcag gacaccgcgg gcgccccgcc cgggcggcgc gagauccggg     2040

ccgccaugca guucggcgac accgagauca aggugaccgc cgucgacgug agcacgaacc     2100

gcagcgugcg ggcguccauc gacuuccuga gcaacugagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  3961
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt1)

<400>  3961
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgggaga ugaccauccu gggcagcgcc gugcucaccc      120

ugcugcucgc gggguaccug gcccagcagu accugccccu cccgacgccc aaggucaucg      180

gcaucgaccu ggggaccacc uacugcuccg ugggcguguu cuuccccggg accggcaagg      240

ucaaggugau ccccgacgag aacggccaca ucagcauccc guccauggug agcuucacgg      300

acaacgacgu cuacgugggg uacgaguccg uggagcuggc cgacagcaac ccccagaaca      360

ccaucuacga cgccaagcgg uucaucggca agaucuucac cgccgaggag cucgaggcgg      420

agaucgggcg cuaccccuuc aagguccuga acaagaacgg caugguggag uucuccguga      480

ccagcaacga gacgaucacc gucucccccg aguacguggg gagccggcug cuccugaagc      540

ugaaggagau ggccgaggcc uaccucggca ugccgguggc caacgcgguc aucuccgugc      600

ccgccgaguu cgaccugaag cagcgcaaca gcaccaucga ggccgccaac cuggccggcc      660

ucaagauccu gcgggugauc aacgagccca ccgcggccgc cauggccuac gggcugcaca      720

aggccgacgu cuuccacgug cucgugaucg accugggcgg gggcacgcug gacgucuccc      780

uccugaacaa gcagggcggg auguuccuga cccgcgcgau gagcggcaac aacaagcucg      840

ggggccagga cuucaaccag cggcugcugc aguaccucua caagcagauc uaccagaccu      900

acggguucgu gcccucccgc aaggaggaga uccaccggcu gcgccaggcc guggagaugg      960

ucaagcugaa ccucacccug caccagagcg cccagcuguc cgugcuccug acggucgagg     1020

agcaggaccg gaaggagccg cacagcuccg acaccgagcu gcccaaggac aagcucagca     1080

gcgccgacga ccaccgcgug aacuccggcu ucggccgggg gcugagcgac aagaaguccg     1140

gcgagagcca ggugcuguuc gagaccgaga ucucccgcaa gcuguucgac acccugaacg     1200

aggaccuguu ccagaagauc cucgucccca uccagcaggu ccugaaggag gggcaccugg     1260

agaagacgga gaucgacgag guggugcucg ugggcgggag cacccggauc ccccgcaucc     1320

gccaggugau ccaggaguuc uucggcaagg acccgaacac cuccgucgac cccgaccugg     1380

ccguggugac cggcgucgcg auccaggccg ggaucgacgg cgggagcugg ccccuccagg     1440

uguccgcccu ggagaucccc aacaagcacc uccagaagac gaacuucaac ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  3962
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt1)

<400>  3962
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgccaucg gcgugcaccu ggggugcacc agcgcgugcg      120

ucgccgugua caaggacggc cgcgccgggg uggucgccaa cgacgccggc gaccggguga      180

cccccgcggu ggucgccuac uccgagaacg aggagaucgu ggggcucgcc gccaagcaga      240

gccgcauccg gaacaucucc aacacgguga ugaaggucaa gcagauccug ggccgcagcu      300

ccagcgaccc gcaggcgcag aaguacaucg ccgaguccaa gugccuggug aucgagaaga      360

acggcaagcu ccgguacgag aucgacaccg gggaggagac caaguucgug aaccccgagg      420

acgucgcccg ccugaucuuc agcaagauga aggagaccgc ccacuccgug cugggcagcg      480

acgccaacga cguggucauc acggugcccu ucgacuucgg ggagaagcag aagaacgcgc      540

ucggcgaggc cgcccgggcc gccggguuca acgugcugcg ccugauccac gagcccuccg      600

cggcccuccu ggccuacggc aucggccagg acagcccgac cgggaagucc aacauccugg      660

ucuucaagcu cggcgggacc agccuguccc ugagcgugau ggaggugaac uccggcaucu      720

accggguccu cagcaccaac acggacgaca acaucggcgg ggcccacuuc accgagaccc      780

uggcccagua ccuggcgucc gaguuccagc gcagcuucaa gcacgacgug cggggcaacg      840

cccgcgccau gaugaagcuc accaacagcg ccgagguggc caagcacucc cugagcacgc      900

ugggguccgc gaacugcuuc cucgacagcc uguacgaggg ccaggacuuc gacugcaacg      960

ucucccgggc ccgcuucgag cugcucugca gcccccuguu caacaagugc aucgaggcca     1020

uccgggggcu gcucgaccag aacggcuuca ccgccgacga caucaacaag gugguccugu     1080

gcggcggguc cagccgcauc cccaagcugc agcagcucau caaggaccug uuccccgcgg     1140

uggagcugcu caacuccauc ccgcccgacg aggugauccc caucggcgcc gccaucgagg     1200

ccgggauccu gaucggcaag gagaaccugc ucgucgagga cagccugaug aucgagugcu     1260

ccgcccggga cauccuggug aagggggugg acgagagcgg cgcgucccgc uucaccgucc     1320

ucuuccccag cggcaccccg cugcccgccc ggcgccagca cacgcugcag gcccccgggu     1380

ccaucagcuc cgugugccuc gagcuguacg agagcgacgg caagaacucc gccaaggagg     1440

agaccaaguu cgcccaggug guccugcagg accucgacaa gaaggagaac gggcugcggg     1500

acauccuggc ggugcucacc augaagcgcg acggcagccu gcacgugacc ugcacggacc     1560

aggagaccgg gaagugcgag gccaucagca ucgagaucgc cuccugagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  3963
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt1)

<400>  3963
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gccuggacgu ggggucccag agcugcuaca      120

ucgccguggc ccgcgcgggc gggaucgaga ccaucgccaa cgaguucucc gaccggugca      180

cccccagcgu caucuccuuc ggcagcaaga accgcaccau cgggguggcc gccaagaacc      240

agcagaucac ccacgccaac aacaccgugu ccaacuucaa gcgguuccac ggccgcgcgu      300

ucaacgaccc guucauccag aaggagaagg agaaccucag cuacgaccug gucccccuga      360

agaacggcgg ggugggcauc aaggugaugu acauggggga ggagcaccuc uucuccgucg      420

agcagaucac cgccaugcug cugacgaagc ucaaggagac cgccgagaac agccugaaga      480

agcccgugac cgacugcgug aucuccgucc ccagcuucuu caccgacgcc gagcggcgcu      540

ccgugcugga cgcggcccag aucgugggcc ucaacugccu gcggcugaug aacgacauga      600

cggccgucgc ccucaacuac gggaucuaca agcaggaccu gccgagccug gacgagaagc      660

cccgcaucgu gguguucguc gacaugggcc acuccgccuu ccaggugagc gcgugcgccu      720

ucaacaaggg caagcucaag gugcugggga ccgccuucga ccccuuccug ggcgggaaga      780

acuucgacga gaagcucguc gagcacuucu gcgccgaguu caagaccaag uacaagcugg      840

acgccaaguc caagauccgg gcgcugcucc gccuguacca ggagugcgag aagcugaaga      900

agcucaugag cuccaacagc accgaccugc cccugaacau cgagugcuuc augaacgaca      960

aggacgugag cggcaagaug aaccgguccc aguucgagga gcucugcgcc gagcugcugc     1020

agaagaucga ggugccgcuc uacagccugc uggagcagac gcaccucaag gucgaggacg     1080

uguccgccgu cgagaucgug ggcggggcca cccgcauccc cgccgugaag gagcggaucg     1140

cgaaguucuu cggcaaggac aucagcacca cccugaacgc cgacgaggcc gucgcccgcg     1200

ggugcgcccu gcagugcgcg auccucuccc ccgccuucaa ggugcgggag uucagcguga     1260

cggacgccgu ccccuucccg aucucccuga ucuggaacca cgacagcgag gacaccgagg     1320

gcgugcacga gguguucucc cgcaaccacg ccgcgcccuu cagcaagguc cugaccuucc     1380

uccggcgcgg gcccuucgag cuggaggccu ucuacuccga cccccagggc gugccguacc     1440

ccgaggccaa gaucggccgg uucguggucc agaacgugag cgcccagaag gacggggaga     1500

agucccgcgu gaaggucaag gugcggguga acacccacgg caucuucacg aucagcaccg     1560

ccuccauggu cgagaaggug cccaccgagg agaacgagau gagcuccgag gcggacaugg     1620

agugccugaa ccagcggccc ccggagaacc ccgacaccga caagaacgug cagcaggaca     1680

acagcgaggc cgggacgcag ccccaggucc agaccgacgc ccagcagacc ucccagagcc     1740

cgcccagccc cgagcucacc uccgaggaga acaagauccc cgacgccgac aaggccaacg     1800

agaagaaggu ggaccagccc ccggaggcga agaagcccaa gaucaaggug gucaacgugg     1860

agcugcccau cgaggccaac cugguguggc agcucggcaa ggaccugcug aacauguaca     1920

ucgagacgga ggggaagaug aucaugcagg acaagcucga gaaggagcgc aacgacgcca     1980

agaacgccgu cgaggaguac guguacgagu uccgcgacaa gcugugcggc ccguacgaga     2040

aguucaucug cgagcaggac caccagaacu uccugcgccu gcucaccgag accgaggacu     2100

ggcuguacga ggagggcgag gaccaggcca agcaggcgua cguggacaag cuggaggagc     2160

ucaugaagau cgggaccccc gucaaggugc gguuccagga ggccgaggag cgccccaaga     2220

uguucgagga gcugggccag cggcugcagc acuacgccaa gaucgccgcg gacuuccgca     2280

acaaggacga gaaguacaac cacaucgacg agagcgagau gaagaaggug gagaaguccg     2340

ucaacgaggu gauggagugg augaacaacg ugaugaacgc ccaggccaag aagucccucg     2400

accaggaccc cgucgugcgg gcccaggaga ucaagacgaa gaucaaggag cugaacaaca     2460

cgugcgagcc gguggucacc cagcccaagc ccaagaucga gagccccaag cuggagcgca     2520

ccccgaacgg gcccaacauc gacaagaagg aggaggaccu cgaggacaag aacaacuucg     2580

gcgccgagcc gccccaccag aacggggagu gcuaccccaa cgagaagaac agcgugaaca     2640

uggaccugga cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  3964
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt1)

<400>  3964
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg ugcgccggca gcgcccccgg cgccgggucu      120

gcugggcccu gguggcggug cuccuggccg accugcucgc ccugagcgac acccuggccg      180

ucauguccgu ggaccucggc agcgagucca ugaagguggc caucgucaag ccgggggugc      240

ccauggagau cgugcugaac aaggagagcc gccggaagac ccccgucauc gugacgcuga      300

aggagaacga gcgcuucuuc ggcgacuccg cggccagcau ggccaucaag aaccccaagg      360

ccacccuccg guacuuccag caccuccugg ggaagcaggc ggacaacccg cacguggccc      420

uguaccaggc ccgcuucccc gagcacgagc ugaccuucga cccccagcgg cagaccgucc      480

acuuccagau cuccagccag cugcaguucu cccccgagga ggugcucggc auggugcuga      540

acuacagccg cucccuggcc gaggacuucg ccgagcagcc gaucaaggac gcggucauca      600

cggugcccgu guucuucaac caggccgagc ggcgcgccgu ccuccaggcc gcccggaugg      660

cggggcugaa ggugcugcag cucaucaacg acaacaccgc caccgcccug agcuacggcg      720

uguuccgccg gaaggacauc aacaccacgg cccagaacau cauguucuac gacaugggcu      780

ccgggagcac cgucugcacc aucgugaccu accagauggu gaagacgaag gaggccggca      840

ugcagcccca gcugcagauc cgcggggucg gcuucgaccg gacccucggg ggccuggaga      900

uggagcugcg ccuccgggag cgccuggcgg gccuguucaa cgagcagcgc aaggggcagc      960

gggccaagga cgugcgcgag aacccccggg ccauggccaa gcuccugcgc gaggccaacc     1020

ggcugaagac cguccucucc gcgaacgccg accacauggc ccagaucgag ggccugaugg     1080

acgacgugga cuucaaggcc aaggugaccc gcgucgaguu cgaggagcug ugcgcggacc     1140

ucuucgagcg ggugccgggg cccgugcagc aggcccugca gagcgccgag augucccugg     1200

acgagaucga gcaggucauc cucgugggcg gcgccacgcg cgugccccgg guccaggagg     1260

ugcugcugaa ggccgugggg aaggaggagc ucggcaagaa caucaacgcg gacgaggccg     1320

ccgccauggg ggccgucuac caggcggccg cccugagcaa ggccuucaag gugaagcccu     1380

ucgugguccg cgacgccgug guguacccga uccuggucga guucacccgg gagguggagg     1440

aggagcccgg cauccacucc cucaagcaca acaagcgcgu gcuguucagc cggauggggc     1500

ccuaccccca gcgcaagguc aucaccuuca accgguacag ccacgacuuc aacuuccaca     1560

ucaacuacgg cgaccugggc uuccucgggc cggaggaccu gcgcguguuc ggcucccaga     1620

accugaccac ggugaagcug aagggggucg gcgacagcuu caagaaguac cccgacuacg     1680

aguccaaggg gaucaaggcg cacuucaacc ucgacgagag cggcgugcug ucccuggacc     1740

ggguggagag cgucuucgag acccucgugg aggacuccgc cgaggaggag agcacccuga     1800

ccaagcuggg caacacgauc uccagccucu ucgggggcgg gaccaccccc gacgccaagg     1860

agaacggcac cgacacggug caggaggagg aggagucccc cgccgagggg agcaaggacg     1920

agccgggcga gcaggucgag cugaaggagg aggcggaggc ccccguggag gacggcuccc     1980

agccgccgcc gcccgagccc aagggggacg ccacccccga gggcgagaag gccaccgaga     2040

aggagaacgg ggacaagagc gaggcccaga agcccuccga gaaggcggag gccggccccg     2100

agggcguggc ccccgccccc gagggggaga agaagcagaa gcccgcccgc aagcggcgca     2160

uggucgagga gaucggcgug gagcuggugg uccucgaccu gcccgaccug cccgaggaca     2220

agcucgcgca gagcgugcag aagcugcagg accugacccu ccgcgaccug gagaagcagg     2280

agcgggagaa ggccgccaac ucccuggagg ccuucaucuu cgagacgcag gacaagcucu     2340

accagccgga guaccaggag gugagcaccg aggagcagcg cgaggagauc uccgggaagc     2400

ugagcgccgc gagcaccugg cuggaggacg agggcgucgg ggccaccacg gugaugcuca     2460

aggagaagcu ggccgagcug cggaagcucu gccagggccu guucuuccgc guggaggagc     2520

ggaagaagug gcccgagcgc cuguccgccc ucgacaaccu gcugaaccac agcuccaugu     2580

uccucaaggg cgcgcggcug auccccgaga uggaccagau cuucaccgag gucgagauga     2640

ccacccugga gaaggugauc aacgagaccu gggccuggaa gaacgccacg cucgccgagc     2700

aggccaagcu gcccgcgacc gagaagccgg ugcugcucag caaggacauc gaggccaaga     2760

ugauggcccu ggaccgcgag guccaguacc ugcucaacaa ggccaaguuc accaagcccc     2820

ggccccgccc caaggacaag aacgggaccc gggccgagcc gccccugaac gcguccgcca     2880

gcgaccaggg cgagaaggug aucccgcccg ccgggcagac ggaggacgcc gagcccaucu     2940

ccgagcccga gaagguggag accggcagcg agcccgggga caccgagccc cuggagcucg     3000

gcggcccggg ggccgagccc gagcagaagg agcaguccac cggccagaag cgcccccuga     3060

agaacgacga gcugugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  3965
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt1)

<400>  3965
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaga cccagaccca ggaccagccc auggaggagg      120

aggaggugga gacguucgcc uuccaggccg agaucgcgca gcugaugagc cucaucauca      180

acaccuucua cuccaacaag gagaucuucc ugcgcgagcu gaucagcaac uccagcgacg      240

cccucgacaa gauccgguac gagucccuga ccgaccccag caagcuggac uccggcaagg      300

agcuccacau caaccugauc cccaacaagc aggaccgcac ccugacgauc gucgacaccg      360

ggaucggcau gaccaaggcc gaccucauca acaaccuggg gaccaucgcc aagagcggca      420

cgaaggccuu cauggaggcg cugcaggccg gggccgacau cuccaugauc ggccaguucg      480

gcgugggguu cuacagcgcc uaccucgugg cggagaaggu caccgugauc accaagcaca      540

acgacgacga gcaguacgcc ugggagucca gcgccggcgg guccuucacc gugcggacgg      600

acaccggcga gcccaugggg cgcggcacca aggucauccu gcaccugaag gaggaccaga      660

ccgaguaccu cgaggagcgg cgcaucaagg agaucgugaa gaagcacagc caguucaucg      720

gcuacccgau cacgcuguuc guggagaagg agcgggacaa ggaggucucc gacgacgagg      780

ccgaggagaa ggaggacaag gaggaggaga aggagaagga ggagaaggag agcgaggaca      840

agcccgagau cgaggacgug ggguccgacg aggaggagga gaagaaggac ggcgacaaga      900

agaagaagaa gaagaucaag gagaaguaca ucgaccagga ggagcugaac aagaccaagc      960

ccaucuggac ccgcaacccc gacgacauca ccaacgagga guacggggag uucuacaaga     1020

gccucacgaa cgacugggag gaccaccugg ccgugaagca cuucuccguc gagggccagc     1080

uggaguuccg ggcgcuccug uucgugccgc gccgggcccc cuucgaccug uucgagaacc     1140

gcaagaagaa gaacaacauc aagcucuacg ugcggcgcgu cuucaucaug gacaacugcg     1200

aggagcugau ccccgaguac cugaacuuca uccggggcgu gguggacagc gaggaccucc     1260

cccugaacau cagccgcgag augcugcagc aguccaagau ccucaagguc auccggaaga     1320

accuggugaa gaagugccug gagcuguuca ccgagcucgc cgaggacaag gagaacuaca     1380

agaaguucua cgagcaguuc agcaagaaca ucaagcuggg gauccacgag gacucccaga     1440

accgcaagaa gcucagcgag cugcugcggu acuacaccuc cgccagcggc gacgagaugg     1500

ugucccucaa ggacuacugc acccgcauga aggagaacca gaagcacauc uacuacauca     1560

cgggggagac caaggaccag gucgccaaca gcgcguucgu ggagcggcug cgcaagcacg     1620

gccuggaggu gaucuacaug aucgagccga ucgacgagua cugcguccag cagcucaagg     1680

aguucgaggg gaagacccug guguccguca ccaaggaggg ccuggagcuc cccgaggacg     1740

aggaggagaa gaagaagcag gaggagaaga agacgaaguu cgagaaccug ugcaagauca     1800

ugaaggacau ccuggagaag aagguggaga agguggucgu gagcaaccgc cucgugaccu     1860

cccccugcug caucgucacc agcaccuacg gcuggacggc caacauggag cggaucauga     1920

aggcccaggc ccugcgcgac aacuccacca ugggguacau ggccgcgaag aagcaccugg     1980

agaucaaccc cgaccacagc aucaucgaga cccugcggca gaaggccgag gccgacaaga     2040

acgacaaguc cgugaaggac cucgugaucc ugcuguacga gaccgcccuc cugagcuccg     2100

gcuucagccu ggaggacccg cagacgcacg ccaaccgcau cuaccggaug aucaagcucg     2160

ggcugggcau cgacgaggac gaccccaccg cggacgacac cuccgccgcc gucaccgagg     2220

agaugccgcc ccuggagggg gacgacgaca ccagccgcau ggaggaggug gacugaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  3966
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt1)

<400>  3966
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucca agcuggacag cggcaagggg cuccacauca      120

accuggugcc caacaagcag aaccagaccc ugaccaucgu cgacacgcgc aucggcauga      180

ccaagaccga ccucaucaac aaccugggga ccgugacgaa guccggcacc aaggccuuca      240

uggaggcccu gcaggcggac gccgacauca gcaugaucgg gcacuucggc gugggcuucu      300

acuccgccua ccucgucgcc aagaagguga ccgugaucag caagcacaac aacgacgagc      360

aguacaccug ggaguccagc gccgggggcu ccuucacggu ccggaccgac gagugaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  3967
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt1)

<400>  3967
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggagg ugcaccacgg cgaggaggag gucgagaccu      120

ucgccuucca ggccgagauc gcgcagcuga ugagccucau caucaacacc uucuacucca      180

acaaggagau cuuccugcgc gagcugauca gcaacgccuc cgacgcccuc gacaagaucc      240

gguacgagag ccugacggac ccguccaagc uggacagcgg gaaggagcuc aagaucgaca      300

ucauccccaa cccccaggag cgcacccuga cccuggugga caccggcauc gggaugacga      360

aggccgaccu caucaacaac cugggcacca ucgccaaguc cgggaccaag gcguucaugg      420

aggcccugca ggccggcgcc gacaucagca ugaucggcca guucggggug ggcuucuacu      480

ccgcguaccu cgucgccgag aagguggugg ucaucaccaa gcacaacgac gacgagcagu      540

acgccuggga gagcuccgcc gggggcagcu ucacggugcg ggccgaccac ggggagccca      600

ucggccgcgg caccaaggug auccugcacc ugaaggagga ccagaccgag uaccucgagg      660

agcggcgcgu caaggaggug gugaagaagc acucccaguu caucggguac ccgaucaccc      720

uguaccugga gaaggagcgg gagaaggaga ucagcgacga cgaggcggag gaggagaagg      780

gcgagaagga ggaggaggac aaggacgacg aggagaagcc caagaucgag gacgucgggu      840

ccgacgagga ggacgacagc ggcaaggaca agaagaagaa gacgaagaag aucaaggaga      900

aguacaucga ccaggaggag cucaacaaga ccaagcccau cuggacccgc aaccccgacg      960

acaucaccca ggaggaguac ggcgaguucu acaagucccu gacgaacgac ugggaggacc     1020

accuggccgu gaagcacuuc agcguggagg ggcagcucga guuccgggcc cugcuguuca     1080

ucccgcgccg ggcccccuuc gaccucuucg agaacaagaa gaagaagaac aacaucaagc     1140

uguacguccg ccggguguuc aucauggacu ccugcgacga gcugaucccc gaguaccuca     1200

acuucauccg cggcgugguc gacagcgagg accugccccu gaacaucagc cgggagaugc     1260

uccagcaguc caagauccug aaggugaucc gcaagaacau cgugaagaag ugccuggagc     1320

uguucagcga gcucgccgag gacaaggaga acuacaagaa guucuacgag gcguucucca     1380

agaaccugaa gcucgggauc cacgaggaca gcaccaaccg gcgccggcug uccgagcugc     1440

uccgcuacca caccagccag uccggcgacg agaugaccag ccuguccgag uacgucagcc     1500

ggaugaagga gacgcagaag uccaucuacu acaucaccgg ggagagcaag gagcaggucg     1560

ccaacuccgc cuucguggag cgcgugcgca agcggggcuu cgaggugguc uacaugaccg     1620

agccgaucga cgaguacugc gugcagcagc ugaaggaguu cgacggcaag agccucgugu     1680

ccgucaccaa ggaggggcug gagcugcccg aggacgagga ggagaagaag aagauggagg     1740

agagcaaggc caaguucgag aaccucugca agcugaugaa ggagauccug gacaagaagg     1800

uggagaaggu gacgaucucc aaccgccucg ucagcucccc cugcugcauc gugaccagca     1860

ccuacggcug gaccgccaac auggagcgga ucaugaaggc gcaggcccug cgcgacaaca     1920

gcacgauggg guacaugaug gccaagaagc accuggagau caaccccgac cacccgaucg     1980

uggagacccu gcggcagaag gccgaggccg acaagaacga caaggcgguc aaggaccucg     2040

uggugcugcu guucgagacc gcccuccugu ccagcggcuu cucccuggag gacccccaga     2100

cccacagcaa ccgcaucuac cggaugauca agcucgggcu gggcaucgac gaggacgagg     2160

ucgccgccga ggagcccaac gcggccgugc ccgacgagau cccgccccug gagggcgacg     2220

aggacgccuc ccgcauggag gagguggacu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  3968
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt1)

<400>  3968
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcgcccugu gggugcucgg ccugugcugc guccugcuca      120

ccuucgggag cgugcgggcc gacgacgagg uggacgucga cggcaccgug gaggaggacc      180

uggggaaguc ccgcgagggc agccggacgg acgacgaggu gguccagcgc gaggaggagg      240

cgauccagcu ggacgggcuc aacgccuccc agauccggga gcugcgcgag aaguccgaga      300

aguucgccuu ccaggccgag gugaaccgga ugaugaagcu gaucaucaac agccucuaca      360

agaacaagga gaucuuccug cgcgagcuga ucagcaacgc cuccgacgcg cucgacaaga      420

uccggcugau cagccugacc gacgagaacg cccucuccgg caacgaggag cugaccguga      480

agaucaagug cgacaaggag aagaaccugc uccacgucac cgacacgggc guggggauga      540

cccgcgagga gcuggugaag aaccugggca ccaucgccaa gagcgggacc uccgaguucc      600

ucaacaagau gacggaggcc caggaggacg gccagagcac cuccgagcug aucgggcagu      660

ucggcgucgg cuucuacagc gcguuccugg uggccgacaa ggugaucguc accuccaagc      720

acaacaacga cacccagcac aucugggaga gcgacuccaa cgaguucagc gugaucgccg      780

acccccgggg gaacacgcuc ggccgcggga ccaccaucac ccuggugcug aaggaggagg      840

ccuccgacua ccucgagcug gacacgauca agaaccuggu caagaaguac agccaguuca      900

ucaacuuccc gaucuacgug uggagcucca agaccgagac cguggaggag cccauggagg      960

aggaggaggc cgcgaaggag gagaaggagg agagcgacga cgaggccgcc gucgaggagg     1020

aggaggagga gaagaagccc aagaccaaga agguggagaa gacggugugg gacugggagc     1080

ucaugaacga caucaagccc aucuggcagc ggccguccaa ggaggucgag gaggacgagu     1140

acaaggccuu cuacaagagc uucuccaagg agagcgacga ccccauggcc uacauccacu     1200

ucaccgcgga gggcgaggug accuucaagu ccauccuguu cguccccacc agcgcgcccc     1260

gcggccuguu cgacgaguac ggguccaaga aguccgacua caucaagcuc uacgugcggc     1320

gcguguucau cacggacgac uuccacgaca ugaugccgaa guaccugaac uucgucaagg     1380

gcguggugga cagcgacgac cugccccuca acgucagccg ggagacccug cagcagcaca     1440

agcugcucaa ggugauccgc aagaagcugg ugcggaagac ccuggacaug aucaagaaga     1500

ucgccgacga caaguacaac gacaccuucu ggaaggaguu cgggacgaac aucaagcucg     1560

gcgucaucga ggaccacucc aaccgcaccc ggcuggccaa gcugcuccgc uuccagagcu     1620

cccaccaccc caccgacauc accagccugg accaguacgu ggagcgcaug aaggagaagc     1680

aggacaagau cuacuucaug gccgggucca gccggaagga ggccgagucc agccccuucg     1740

uggagcgccu gcucaagaag ggcuacgagg ucaucuaccu gacggagccg guggacgagu     1800

acugcaucca ggcccugccc gaguucgacg gcaagcgguu ccagaacgug gccaaggagg     1860

gggucaaguu cgacgagagc gagaagacca aggagucccg cgaggccgug gagaaggagu     1920

ucgagccccu gcucaacugg augaaggaca aggcccugaa ggacaagauc gagaaggcgg     1980

uggucagcca gcggcugacc gagucccccu gcgcccucgu ggccagccag uacggcuggu     2040

ccgggaacau ggagcgcauc augaaggccc aggcguacca gaccggcaag gacaucagca     2100

cgaacuacua cgccucccag aagaagaccu ucgagaucaa cccgcggcac ccccugaucc     2160

gcgacaugcu gcggcgcauc aaggaggacg aggacgacaa gaccgugcuc gaccuggccg     2220

ucgugcuguu cgagaccgcc acccuccgga gcggguaccu gcugcccgac acgaaggccu     2280

acggcgaccg caucgagcgg augcuccgcc ugucccugaa caucgacccc gacgcgaagg     2340

uggaggagga gccggaggag gagcccgagg agaccgccga ggacaccacc gaggacacgg     2400

agcaggacga ggacgaggag auggacgucg gcaccgacga ggaggaggag accgccaagg     2460

agagcaccgc cgagaaggac gagcucugag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  3969
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt1)

<400>  3969
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgcgagc ugcgggcccu ccugcugugg ggccgccggc      120

uccgcccccu gcugcgggcg ccggcccucg ccgccgugcc cgggggcaag cccauccugu      180

gcccccgccg gaccaccgcc cagcuggggc cgcgccggaa ccccgcgugg agccuccagg      240

ccggccgccu guucuccacg cagaccgccg aggacaagga ggagccccug cacagcauca      300

ucuccagcac cgaguccguc caggggagca ccuccaagca cgaguuccag gccgagacga      360

agaagcuccu ggacaucgug gcgcggagcc uguacuccga gaaggaggug uucauccgcg      420

agcucaucag caacgccucc gacgcccugg agaagcugcg gcacaagcuc gucagcgacg      480

gccaggcccu gcccgagaug gagauccacc uccagaccaa cgccgagaag ggcaccauca      540

ccauccagga cacggggauc ggcaugaccc aggaggagcu gguguccaac cuggggacca      600

ucgcgcgcag cggcuccaag gccuuccugg acgcccucca gaaccaggcc gaggccagcu      660

ccaagaucau cgggcaguuc ggcgugggcu ucuacagcgc guucaugguc gccgaccggg      720

uggaggugua cucccgcagc gccgccccgg ggagccuggg cuaccagugg cuguccgacg      780

ggagcggcgu cuucgagauc gccgaggcgu ccggcgugcg gaccgggacg aagaucauca      840

uccaccucaa gagcgacugc aaggaguucu ccagcgaggc ccgcgugcgg gacgucguga      900

ccaaguacuc caacuucgug agcuuccccc uguaccugaa cggccgccgg augaacaccc      960

uccaggccau cuggaugaug gaccccaagg acguccgcga guggcagcac gaggaguucu     1020

accgcuacgu ggcccaggcc cacgacaagc cccgguacac ccugcacuac aagacggacg     1080

cgccgcugaa cauccgcucc aucuucuacg ugcccgacau gaagcccagc auguucgacg     1140

ucucccggga gcucgggagc uccguggccc uguacagccg caaggugcug auccagacca     1200

aggccaccga cauccucccc aaguggcugc gguucauccg cggcgucgug gacuccgagg     1260

acaucccgcu gaaccucagc cgggagcugc ugcaggaguc cgcccucauc cgcaagcugc     1320

gggacgugcu gcagcagcgc cucaucaagu ucuucaucga ccagagcaag aaggacgcgg     1380

agaaguacgc caaguucuuc gaggacuacg ggcuguucau gcgggagggc aucgucaccg     1440

ccacggagca ggaggugaag gaggacaucg ccaagcugcu ccgcuacgag uccagcgccc     1500

ugcccagcgg ccagcugacc ucccugagcg aguacgcguc ccggaugcgc gccgggaccc     1560

ggaacaucua cuaccucugc gcccccaacc gccaccuggc cgagcacagc cccuacuacg     1620

aggccaugaa gaagaaggac accgaggucc uguucugcuu cgagcaguuc gacgagcuca     1680

cgcugcugca ccuccgggag uucgacaaga agaagcugau cuccguggag accgacaucg     1740

uggucgacca cuacaaggag gagaaguucg aggaccgcag cccggcggcc gagugccugu     1800

ccgagaagga gaccgaggag cucauggccu ggaugcggaa cgugcugggc agccgcguga     1860

ccaacgucaa ggugacgcug cgccucgaca cccaccccgc cauggugacc guccuggaga     1920

ugggggccgc gcggcacuuc cugcgcaugc agcagcucgc caagacccag gaggagcggg     1980

cccagcugcu gcagcccacg cucgagauca acccccgcca cgcccugauc aagaagcuga     2040

accagcuccg ggcguccgag ccgggccugg cccagcugcu cguggaccag aucuacgaga     2100

acgccaugau cgccgccggg cugguggacg acccccgcgc gauggucggc cggcugaacg     2160

agcuccuggu gaaggcccug gagcgccacu gaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  3970
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt1)

<400>  3970
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagauca gcucccugcc cacccagcug uucaagugcu      120

gcuucugcga cuuccucaag gugaagaugc acaccaugag cuccagccac cuguucuacc      180

ucgcccugug ccugcucacg uucaccucca gcgccaccgc ggggccggag acccugugcg      240

gcgccgagcu ggucgacgcc cuccaguucg ugugcgggga ccgcggcuuc uacuucaaca      300

agcccacggg guacggcucc agcucccggc gcgcgcccca gaccggcauc guggacgagu      360

gcugcuuccg gagcugcgac cugcgccggc uggagaugua cugcgcgccc cucaagccgg      420

ccaaguccgc ccgcagcguc cgggcccagc gccacaccga caugcccaag acccagaagg      480

aggugcaccu gaagaacgcc ucccggggga gcgccggcaa caagaacuac cgcaugugag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  3971
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt1)

<400>  3971
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca uggggaaguc caugcuggug cuccugaccu      120

uccuggccuu cgccagcugc ugcaucgcgg ccuaccgccc gagcgagacc cucugcggcg      180

gggagcuggu cgacacgcug caguucgugu gcggcgaccg gggguucuac uucucccgcc      240

ccgccagccg ggugucccgc cggagccgcg gcaucgucga ggagugcugc uuccgguccu      300

gcgaccucgc ccugcuggag accuacugcg ccacccccgc caagagcgag cgcgacgugu      360

ccacgccccc gaccgugcuc cccgacaacu ucccccggua ccccgucggc aaguucuucc      420

aguacgacac cuggaagcag agcacccagc gccugcggcg cgggcugccg gcgcuccugc      480

gggcccgccg gggccacgug cuggccaagg agcucgaggc guuccgcgag gccaagcggc      540

accgcccccu gaucgcccug cccacccagg accccgccca cgggggcgcc ccgcccgaga      600

uggcguccaa ccggaaguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  3972
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt1)

<400>  3972
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagcuucu ccaccagcgc cuucggcccc guggccuucu      120

cccuggggcu ccugcugguc cucccggcgg ccuuccccgc ccccgugccc ccgggcgagg      180

acagcaagga cguggccgcg ccccaccgcc agccccugac cuccagcgag cggaucgaca      240

agcagauccg cuacauccug gacgggaucu ccgcccuccg gaaggagacg ugcaacaaga      300

gcaacaugug cgaguccagc aaggaggccc uggccgagaa caaccugaac cuccccaaga      360

uggccgagaa ggacggcugc uuccaguccg gguucaacga ggagaccugc cuggucaaga      420

ucaucaccgg ccugcucgag uucgaggugu accuggagua ccugcagaac cgcuucgaga      480

gcuccgagga gcaggcgcgg gccgugcaga ugagcaccaa gguccucauc caguuccugc      540

agaagaaggc caagaaccug gacgccauca cgaccccgga ccccaccacc aacgccuccc      600

uccugacgaa gcugcaggcg cagaaccagu ggcuccagga caugaccacc caccugaucc      660

ugcgcagcuu caaggaguuc cuccagucca gccugcgggc ccugcgccag augugaggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  3973
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt1)

<400>  3973
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcucu ggcugcgcgg cuuccugcuc gccagcugcu      120

ggaucaucgu gcgguccagc ccgacccccg gguccgaggg ccacagcgcc gcgcccgacu      180

gccccuccug cgcccuggcc gcccugccga aggacguccc caacagccag cccgagaugg      240

uggaggccgu gaagaagcac auccucaaca ugcugcaccu gaagaagcgc cccgacguca      300

cccagccggu gcccaaggcg gcccuccuga acgccauccg gaagcugcac guggggaagg      360

ucggcgagaa cggguacgug gagaucgagg acgacaucgg ccgccgggcc gagaugaacg      420

agcucaugga gcagacgucc gagaucauca ccuucgcgga gagcggcacc gcccgcaaga      480

cccugcacuu cgagaucucc aaggagggga gcgaccuguc cguggucgag cgggccgagg      540

uguggcuguu ccucaaggug cccaaggcca accgcacgcg gaccaagguc accauccgcc      600

uguuccagca gcagaagcac ccccagggca gccucgacac cggggaggag gccgaggagg      660

ugggccugaa gggggagcgg uccgagcugc uccugagcga gaaggugguc gacgcgcgca      720

aguccacgug gcacguguuc ccggugagcu ccagcaucca gcggcugcuc gaccagggca      780

aguccagccu ggacguccgc aucgccugcg agcagugcca ggagagcggc gccucccugg      840

ugcuccuggg gaagaagaag aagaaggagg aggagggcga ggggaagaag aagggcggcg      900

gggagggcgg ggccggcgcc gacgaggaga aggagcagag ccaccggccc uuccugaugc      960

uccaggcgcg ccaguccgag gaccaccccc accggcgccg gcgccggggg cuggagugcg     1020

acggcaaggu gaacaucugc ugcaagaagc aguucuucgu cagcuucaag gacaucggcu     1080

ggaacgacug gaucaucgcc cccuccgggu accacgccaa cuacugcgag ggcgagugcc     1140

cgagccacau cgccgggacc uccggcagcu cccugagcuu ccacuccacc gugaucaacc     1200

acuaccgcau gcgcgggcac agccccuucg ccaaccucaa guccugcugc gugcccacca     1260

agcugcggcc caugagcaug cuguacuacg acgacggcca gaacaucauc aagaaggaca     1320

uccagaacau gaucgucgag gagugcggcu gcuccugagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  3974
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt1)

<400>  3974
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccugc ccgggcgcgc ccucggcgcc gcgugccugc      120

ugcuccuggc cgccgggugg cugggcccgg aggccugggg gagccccacc ccgcccccga      180

cccccgccgc gcccccgccc ccgcccccgc ccggcucccc cggcgggagc caggacacgu      240

gcaccuccug cggcggguuc cggcgccccg aggagcucgg ccggguggac ggggacuucc      300

uggaggccgu caagcgccac auccugagcc ggcuccagau gcgcggccgg cccaacauca      360

cccacgccgu gcccaaggcc gcgaugguga ccgcccugcg caagcugcac gccggcaagg      420

uccgggagga cgggcgcgug gagauccccc accucgacgg ccacgccucc cccggggccg      480

acggccagga gcgggugagc gagaucaucu ccuucgcgga gacggacggc cuggccagcu      540

cccgcguccg gcuguacuuc uucaucagca acgaggggaa ccagaaccuc uucguggugc      600

aggccucccu guggcuguac cucaagcugc ugcccuacgu ccucgagaag ggcagccgcc      660

ggaaggugcg cgugaagguc uacuuccagg agcaggggca cggcgaccgg uggaacaugg      720

uggagaagcg cguggaccug aagcgguccg gguggcacac cuucccccug accgaggcca      780

uccaggcccu cuucgagcgc ggcgagcggc gccugaaccu ggacguccag ugcgacagcu      840

gccaggagcu cgcgguggug cccgucuucg uggaccccgg cgaggagucc caccgccccu      900

ucguggucgu gcaggcccgg cugggggaca gccgccaccg gauccgcaag cggggccugg      960

agugcgacgg gcgcaccaac cucugcugcc ggcagcaguu cuucaucgac uuccgccuga     1020

ucggcuggaa cgacuggauc aucgccccga cgggguacua cggcaacuac ugcgagggcu     1080

ccugccccgc cuaccuggcc ggggugcccg gcagcgcguc cagcuuccac accgccgucg     1140

ugaaccagua ccggaugcgc gggcucaacc ccggcaccgu caacagcugc ugcaucccga     1200

ccaagcuguc cacgaugagc augcuguacu ucgacgacga guacaacauc gugaagcggg     1260

acgugcccaa caugaucguc gaggagugcg ggugcgccug aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  3975
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt1)

<400>  3975
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugcgcg ugcuccugcu gaccgcccuc acccugugcc      120

acggcuucaa ccuggacacg gagaacgcga ugaccuucca ggagaacgcc cggggguucg      180

gccagagcgu cgugcagcuc cagggguccc gcguggucgu gggcgccccc caggagaucg      240

uggccgccaa ccagcggggg agccuguacc agugcgacua cuccaccggc agcugcgagc      300

cgauccgccu gcaggucccc guggaggcgg ugaacauguc ccucggccug agccuggccg      360

ccaccacguc ccccccccag cuccuggccu gcgggccgac cguccaccag accugcagcg      420

agaacaccua cgugaagggc cugugcuucc ucuucggguc caaccugcgg cagcagcccc      480

agaaguuccc cgaggcgcug cgcggcugcc cccaggagga cagcgacauc gccuuccuca      540

ucgacggguc cggcagcauc aucccgcacg acuuccggcg caugaaggag uucgugucca      600

cggucaugga gcagcugaag aaguccaaga cccuguucuc ccucaugcag uacagcgagg      660

aguuccggau ccacuucacc uucaaggagu uccagaacaa ccccaacccc cgcucccugg      720

ugaagcccau cacccagcug cucggccgga cgcacaccgc caccgggauc cgcaaggugg      780

uccgggagcu guucaacauc accaacggcg cccgcaagaa cgccuucaag auccuggugg      840

ugaucacgga cggggagaag uucggcgacc cgcucggcua cgaggacguc auccccgagg      900

cggaccggga gggggugauc cgcuacguga ucggcgucgg ggacgccuuc cggagcgaga      960

agucccgcca ggagcugaac accaucgcca gcaagccccc ccgggaccac guguuccagg     1020

ugaacaacuu cgaggcccug aagaccaucc agaaccagcu ccgcgagaag aucuucgcca     1080

ucgagggcac ccagacgggg agcuccagcu ccuucgagca cgagaugagc caggagggcu     1140

ucuccgcggc caucaccagc aacggcccgc ugcuguccac cgucgggagc uacgacuggg     1200

ccggcggggu guuccucuac accuccaagg agaaguccac guucaucaac augacccggg     1260

ucgacuccga caugaacgac gccuaccugg gcuacgccgc ggccaucauc cugcgcaacc     1320

gcgugcagag ccucgugcug ggggcccccc gguaccagca caucggccug gucgccaugu     1380

uccgccagaa caccggcaug ugggagucca acgccaacgu gaaggggacc cagaucggcg     1440

cguacuucgg ggccagccuc ugcuccgugg acgucgacag caacggcucc acggaccugg     1500

ugcugaucgg ggccccccac uacuacgagc agacccgggg cggccaggug agcgucugcc     1560

cccucccgcg cgggcgggcc cgcuggcagu gcgacgcggu gcuguacggc gagcaggggc     1620

agcccugggg ccgguucggc gccgcccuga ccgugcucgg ggacgucaac ggcgacaagc     1680

ugaccgacgu ggccaucggg gcccccggcg aggaggacaa ccgcggggcg guguaccugu     1740

uccacggcac guccggcagc gggaucagcc ccucccacag ccagcggauc gccggcucca     1800

agcucagccc gcgccugcag uacuucgggc agucccugag cggcgggcag gaccugacca     1860

uggacggccu cgucgaccug accgugggcg cccaggggca cgugcugcuc cugcgguccc     1920

agcccguccu gcgcgugaag gccaucaugg aguucaaccc ccgggaggug gcccgcaacg     1980

ucuucgagug caacgaccag guggugaagg gcaaggaggc gggggagguc cgggugugcc     2040

uccacgugca gaaguccacc cgcgaccggc ugcgcgaggg ccagauccag uccgucguga     2100

cguacgaccu ggcccucgac agcgggcggc cccacucccg cgccguguuc aacgagacca     2160

agaacagcac ccgccggcag acccaggucc ugggccugac ccagacgugc gagacccuca     2220

agcugcagcu gccgaacugc aucgaggacc ccgugucccc caucgugcuc cgccugaacu     2280

ucagccuggu cggcaccccg cucuccgccu ucgggaaccu gcggcccgug cuggccgagg     2340

acgcgcagcg ccucuucacc gcccuguucc ccuucgagaa gaacugcggc aacgacaaca     2400

ucugccagga cgaccugagc aucacguucu ccuucaugag ccucgacugc cugguggucg     2460

ggggcccccg ggaguucaac gugaccguga ccguccgcaa cgacggggag gacagcuacc     2520

ggacccaggu gacguucuuc uucccgcugg accucuccua ccgcaaggug agcacccugc     2580

agaaccagcg gucccagcgc agcuggcggc uggccugcga guccgccagc uccaccgagg     2640

ucagcggcgc gcucaagucc accagcugcu ccaucaacca ccccaucuuc cccgagaaca     2700

gcgaggugac guucaacauc accuucgacg uggacuccaa ggccagccug ggcaacaagc     2760

ugcuccugaa ggccaacguc accuccgaga acaacaugcc ccgcaccaac aagacggagu     2820

uccagcugga gcucccggug aaguacgccg uguacauggu cgugaccagc cacggggugu     2880

ccaccaagua ccugaacuuc accgccagcg agaacacguc ccgggucaug cagcaccagu     2940

accaggugag caaccugggc cagcgcagcc uccccaucuc ccuggucuuc cuggugcccg     3000

ugcggcucaa ccagaccguc aucugggacc gcccccaggu gaccuucagc gagaaccugu     3060

ccagcacaug ccacacgaag gagcggcugc cgucccacag cgacuuccuc gcggagcugc     3120

gcaaggcccc cguggucaac ugcuccaucg ccgugugcca gcggauccag ugcgacaucc     3180

ccuucuucgg gauccaggag gaguucaacg ccacccugaa gggcaaccuc agcuucgacu     3240

gguacaucaa gaccucccac aaccaccucc ugaucgugag caccgccgag auccucuuca     3300

acgacuccgu cuucacgcug cugcccggcc agggggcguu cgugcgcagc cagaccgaga     3360

ccaaggugga gccguucgag guccccaacc cccucccccu gaucgugggc uccagcgugg     3420

ggggccugcu ccugcuggcc cucaucaccg ccgcccugua caagcugggg uucuucaagc     3480

ggcaguacaa ggacaugaug uccgagggcg gcccgcccgg ggccgagccc cagugaggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  3976
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt1)

<400>  3976
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucagccuga agacccuccc cuuccugcug cuccugcacg      120

ugcagaucuc caaggccuuc ccggucagcu ccaaggagaa gaacaccaag acggugcagg      180

acuaccugga gaaguucuac cagcucccca gcaaccagua ccaguccacc cgcaagaacg      240

gcaccaacgu gaucgucgag aagcugaagg agaugcagcg guucuucggg cugaacguga      300

ccggcaagcc caacgaggag acgcucgaca ugaugaagaa gccccgcugc ggggugccgg      360

acagcggcgg guucaugcug acccccggca accccaagug ggagcggacc aaccugaccu      420

accgcauccg gaacuacacg ccccagcucu ccgaggccga ggucgagcgc gcgaucaagg      480

acgccuucga gcuguggagc guggccuccc cgcugaucuu cacccggauc agccagggcg      540

aggccgacau caacaucgcc uucuaccagc gcgaccacgg ggacaacucc cccuucgacg      600

gccccaacgg gauccucgcg cacgccuucc agcccggcca ggggaucggc ggcgacgccc      660

acuucgacgc cgaggagacc uggaccaaca cgagcgcgaa cuacaaccug uuccuggugg      720

ccgcccacga guucgggcac ucccucggcc uggcccacag cuccgacccg ggggcccuga      780

uguaccccaa cuacgcguuc cgggagacca gcaacuacuc ccucccccag gacgacaucg      840

acggcaucca ggccaucuac ggccugagcu ccaaccccau ccagccgacc gggcccagca      900

cccccaagcc cugcgacccg agccugacgu ucgacgccau caccacccuc cgcggcgaga      960

uccuguucuu caaggaccgg uacuucuggc gccggcaccc ccagcugcag cgcgucgaga     1020

ugaacuucau cucccucuuc uggcccagcc ugcccaccgg gauccaggcc gccuacgagg     1080

acuucgaccg ggaccugauc uuccucuuca agggcaacca guacugggcg cuguccgggu     1140

acgacauccu gcagggcuac ccgaaggaca ucagcaacua cggcuucccc uccagcgugc     1200

aggccaucga cgccgccgug uucuaccgcu ccaagacgua cuucuucguc aacgaccagu     1260

ucuggcggua cgacaaccag cgccaguuca uggagcccgg guaccccaag agcaucuccg     1320

gcgccuuccc ggggaucgag agcaaggugg acgcgguguu ccagcaggag cacuucuucc     1380

acgucuucuc cggcccccgg uacuacgccu ucgaccucau cgcccagcgc gugacccggg     1440

uggcccgcgg gaacaagugg cugaacugcc gcuacggcug aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  3977
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt1)

<400>  3977
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguggc agccccucgu gcugguccug cucgugcugg      120

gcugcugcuu cgccgccccg cgccagcggc aguccacccu gguccucuuc cccggggacc      180

ugcgcaccaa ccugacggac cggcagcucg cggaggagua ccuguaccgc uacggcuaca      240

cccggguggc cgagaugcgc ggggagagca agucccuggg ccccgcccuc cugcugcucc      300

agaagcagcu gagccugccc gagaccgggg agcucgacuc cgccacccug aaggccaugc      360

ggacgccgcg cugcggcgug cccgaccugg gccgguucca gaccuucgag ggggaccuca      420

aguggcacca ccacaacauc accuacugga uccagaacua cagcgaggac cugccccgcg      480

cggugaucga cgacgccuuc gcccgggccu ucgcgcugug guccgccguc acgccccuca      540

ccuucacccg cguguacagc cgggacgccg acaucgugau ccaguucggc gucgccgagc      600

acggggacgg cuacccguuc gacgggaagg acggccugcu ggcccacgcg uucccgcccg      660

gccccgggau ccagggcgac gcccacuucg acgacgacga gcucuggucc cuggggaagg      720

gcgugguggu ccccacccgc uucggcaacg ccgacggggc cgccugccac uuccccuuca      780

ucuucgaggg ccggagcuac uccgcgugca ccacggacgg gcgcagcgac ggccugcccu      840

ggugcuccac caccgccaac uacgacaccg acgaccgguu cggguucugc cccagcgagc      900

gccucuacac gcaggacggc aacgccgacg gcaagccgug ccaguucccc uucaucuucc      960

aggggcaguc cuacagcgcc ugcaccaccg acggccgguc cgacggguac cgcuggugcg     1020

ccaccacggc gaacuacgac cgggacaagc uguucggcuu cugccccacc cgcgccgaca     1080

gcaccgugau gggcggcaac uccgccggcg agcugugcgu guuccccuuc accuuccucg     1140

ggaaggagua cagcacgugc accagcgagg gccgcgggga cggccggcug uggugcgcca     1200

ccaccuccaa cuucgacagc gacaagaagu ggggguucug cccggaccag ggcuacuccc     1260

uguuccucgu cgccgcgcac gaguucggcc acgcccuggg gcuggaccac agcuccgugc     1320

ccgaggcccu cauguacccc auguaccgcu ucacggaggg gcccccgcug cacaaggacg     1380

acgugaacgg gauccggcac cuguacggcc cccgccccga gcccgagccg cggccgccca     1440

ccaccaccac gccccagccc accgccccgc ccaccgucug ccccaccggc ccgcccacgg     1500

ugcaccccag cgagcgcccc accgcggggc ccaccggccc gcccuccgcc gggcccaccg     1560

gcccgcccac cgccgggccc agcacggcca ccaccgugcc ccucuccccc gucgacgacg     1620

ccugcaacgu gaacaucuuc gacgcgaucg ccgagaucgg caaccagcug uaccuguuca     1680

aggacggcaa guacuggcgg uucagcgagg ggcgcggcuc ccggccccag gggcccuucc     1740

ucaucgccga caaguggccg gcccugcccc gcaagcugga cagcguguuc gaggagcggc     1800

ucuccaagaa gcuguucuuc uucagcggcc gccaggucug gguguacacc ggggccuccg     1860

uccugggccc ccggcgccug gacaagcucg gccugggggc ggacguggcc caggugacgg     1920

gcgcccugcg gagcgggcgc ggcaagaugc uccuguucuc cgggcggcgc cuguggcggu     1980

ucgacgucaa ggcccagaug guggaccccc gcagcgccuc cgagguggac cgcauguucc     2040

cgggcguccc ccucgacacc cacgacgugu uccaguaccg ggagaaggcg uacuucugcc     2100

aggaccgcuu cuacuggcgg gugagcagcc gcuccgagcu gaaccagguc gaccaggugg     2160

gcuacgugac cuacgacauc cugcagugcc ccgaggacug aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  3978
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt1)

<400>  3978
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg ugcuggccgc cuuccucuuc cugagcugga      120

cccacugccg cgcgcugccg cuccccuccg ggggcgacga ggacgaccug agcgaggagg      180

accugcaguu cgccgagcgg uaccuccgcu ccuacuacca ccccaccaac cuggccggga      240

uccugaagga gaacgccgcc agcuccauga cggagcggcu ccgcgagaug cagagcuucu      300

ucggccugga ggucaccggg aagcuggacg acaacacccu cgacgugaug aagaagcccc      360

ggugcggcgu gccggacguc ggcgaguaca acguguuccc ccgcacccug aaguggucca      420

agaugaaccu gacguaccgg aucgugaacu acacccccga caugacccac agcgaggucg      480

agaaggcguu caagaaggcc uucaaggugu gguccgacgu gacgccccuc aacuucaccc      540

gccugcacga cgggaucgcc gacaucauga ucagcuucgg caucaaggag cacggggacu      600

ucuacccguu cgacggcccc uccgggcugc ucgcccacgc guucccgccc ggccccaacu      660

acggcgggga cgcccacuuc gacgacgacg agaccuggac cagcuccagc aagggcuaca      720

accuguuccu ggucgccgcc cacgaguucg ggcacucccu cggccuggac cacagcaagg      780

accccggcgc ccugauguuc cccaucuaca ccuacacggg gaagucccac uucaugcucc      840

ccgacgacga cgugcagggc auccagagcc uguacgggcc gggcgacgag gaccccaacc      900

ccaagcaccc caagaccccg gacaagugcg accccucccu gagccucgac gcgaucacca      960

gccugcgcgg ggagaccaug aucuucaagg accgguucuu cuggcggcug cacccccagc     1020

aggucgacgc cgagcuguuc cugacgaagu ccuucuggcc cgagcugccg aaccgcaucg     1080

acgccgccua cgagcacccc agccacgacc ucaucuucau cuuccggggc cgcaaguucu     1140

gggcccugaa cggcuacgac auccuggagg gguaccccaa gaagaucucc gagcucggcc     1200

ugcccaagga ggugaagaag aucagcgcgg ccgugcacuu cgaggacacc gggaagaccc     1260

uccucuucuc cggcaaccag guguggcggu acgacgacac caaccacauc auggacaagg     1320

acuacccgcg ccugaucgag gaggacuucc ccgggaucgg cgacaagguc gacgccgugu     1380

acgagaagaa cggcuacauc uacuucuuca acgggcccau ccaguucgag uacagcaucu     1440

gguccaaccg gaucgugcgc gucaugccgg ccaacagcau ccuguggugc ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  3979
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt1)

<400>  3979
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acaccacgga ggacuacgac accaccaccg      120

aguucgacua cggcgacgcc acgccgugcc agaaggugaa cgagcgcgcc uucggggcgc      180

agcugcuccc gccccuguac agccuggucu ucgugaucgg ccucgugggg aacauccugg      240

ucgugcuggu gcucguccag uacaagcggc ugaagaacau gaccuccauc uaccugcuca      300

accuggccau cagcgaccuc cucuuccugu ucacccugcc cuucuggauc gacuacaagc      360

ucaaggacga cuggguguuc ggcgacgcca ugugcaagau ccuguccggg uucuacuaca      420

ccggccugua cagcgagauc uucuucauca uccuccugac gaucgaccgc uaccuggcca      480

ucgugcacgc cgucuucgcg cuccgggccc gcaccgugac cuucggcgug aucaccucca      540

ucaucaucug ggcccuggcc auccuggcga gcaugcccgg gcucuacuuc uccaagacgc      600

agugggaguu cacccaccac acgugcagcc ugcacuuccc ccacgagucc cugcgggagu      660

ggaagcuguu ccaggcccug aagcugaacc ucuucggccu gguccugccc cuccugguga      720

ugaucaucug cuacaccggg aucaucaaga uccugcuccg ccggcccaac gagaagaagu      780

ccaaggccgu gcgccugauc uucgucauca ugaucaucuu cuuccuguuc uggaccccgu      840

acaaccucac cauccugauc agcguguucc aggacuuccu guucacccac gagugcgagc      900

agagccggca ccucgaccug gccgugcagg ucaccgaggu gaucgccuac acgcacugcu      960

gcgugaaccc cgucaucuac gcguucgugg gcgagcgcuu ccggaaguac cugcgccagc     1020

uguuccaccg gcgcguggcc guccaccucg ugaaguggcu gcccuuccuc uccgucgacc     1080

ggcuggagcg cgugagcucc accagccccu ccaccgggga gcacgagcug agcgccggcu     1140

ucugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  3980
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt1)

<400>  3980
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcacccugg ccugccuccu gcugcucggc ugcggguacc      120

uggcccacgu gcuggcggag gaggccgaga ucccccggga ggugaucgag cgccucgccc      180

ggagccagau ccacuccauc cgcgaccugc agcggcugcu cgagaucgac agcgugggcu      240

ccgaggacag ccuggacacc ucccugcgcg cccacggggu gcacgccacg aagcacgucc      300

cggagaagcg gccccucccc auccgccgga agcgcagcau cgaggaggcg gugcccgccg      360

ugugcaagac ccggaccguc aucuacgaga ucccgcgcuc ccagguggac cccaccagcg      420

ccaacuuccu gaucuggccg cccugcgugg aggucaagcg gugcacgggc ugcugcaaca      480

ccuccagcgu gaagugccag cccucccgcg ugcaccaccg gagcgucaag guggccaagg      540

uggaguacgu ccgcaagaag cccaagcuga aggaggucca ggugcggcuc gaggagcacc      600

uggagugcgc gugcgccacc accucccuga accccgacua ccgcgaggag gacacggggc      660

ggccccgcga gagcggcaag aagcggaagc gcaagcgccu caagccgacc ugaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  3981
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt1)

<400>  3981
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaccgcugcu gggcccuguu ccucagccug ugcugcuacc      120

ugcggcucgu guccgccgag ggcgacccca ucccggagga gcuguacgag augcugagcg      180

accacuccau ccgcagcuuc gacgaccucc agcggcugcu gcacggggac cccggcgagg      240

aggacggggc ggagcucgac cugaacauga cccgcuccca cagcggcggg gagcuggagu      300

cccucgcccg gggccgccgg agccugggcu cccugaccau cgccgagccc gccaugaucg      360

ccgagugcaa gacgcgcacc gaggucuucg agaucagccg gcgccucauc gaccggacca      420

acgcgaacuu ccuggugugg cccccgugcg uggaggucca gcgcugcucc gggugcugca      480

acaaccggaa cgugcagugc cgccccaccc aggugcagcu gcggcccguc caggugcgca      540

agaucgagau cgugcggaag aagcccaucu ucaagaaggc cacggucacc cucgaggacc      600

accuggccug caagugcgag accguggccg cggcccgccc ggugacccgg agccccggcg      660

ggucccagga gcagcgcgcc aagacgcccc agacccgggu caccauccgc accgugcgcg      720

ugcggcggcc cccgaagggc aagcaccgca aguucaagca cacgcacgac aagaccgccc      780

ugaaggagac ccucggggcc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  3982
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt1)

<400>  3982
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguucg gccuccugcu gcucaccucc gcccuggccg      120

ggcagcgcca gggcacccag gcggagagca accuguccag caaguuccag uucuccagca      180

acaaggagca gaacggggug caggaccccc agcacgagcg gaucaucacg gucuccacca      240

acggcagcau ccacuccccg cgcuuccccc acaccuaccc ccggaacacc gugcucgugu      300

ggcgccuggu cgccguggag gagaacgugu ggauccagcu gacguucgac gagcgguucg      360

ggcucgagga ccccgaggac gacaucugca aguacgacuu cgucgaggug gaggagccga      420

gcgacggcac cauccugggc cgcuggugcg gguccggcac cgugcccggg aagcagauca      480

gcaagggcaa ccagauccgg auccgcuucg ucuccgacga guacuucccc agcgagcccg      540

gguucugcau ccacuacaac aucgugaugc cgcaguucac cgaggccgug ucccccagcg      600

uccugccgcc cuccgcccuc ccccuggacc ugcucaacaa cgccaucacg gcguucagca      660

cccuggagga ccugauccgg uaccucgagc ccgagcgcug gcagcuggac cuggaggacc      720

ucuaccggcc caccuggcag cugcugggca aggccuucgu guucggccgc aagucccggg      780

uggucgaccu caaccugcug accgaggagg ugcgccucua cagcugcacg ccccggaacu      840

ucagcguguc cauccgcgag gagcugaagc ggaccgacac caucuucugg ccggggugcc      900

ugcucgucaa gcgcugcggc gggaacugcg ccugcugccu gcacaacugc aacgagugcc      960

agugcgugcc cagcaaggug accaagaagu accacgaggu ccugcagcuc cggcccaaga     1020

cgggcgugcg cggccugcac aagucccuga ccgacguggc ccucgagcac cacgaggagu     1080

gcgacugcgu cugccggggg agcaccggcg ggugaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  3983
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt1)

<400>  3983
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgccuga ucuucgugua cacccucauc ugcgccaacu      120

ucugcagcug ccgggacacc uccgccacgc cccagagcgc guccaucaag gcccugcgca      180

acgccaaccu gcggcgcgac gaccucuacc ggcgcgacga gaccauccag gucaagggca      240

acggguacgu gcagagcccc cgguucccca acuccuaccc ccgcaaccug cugcucaccu      300

ggcggcugca cagccaggag aacacccgca uccagcuggu guucgacaac caguucggcc      360

ucgaggaggc cgagaacgac aucugccggu acgacuucgu cgagguggag gacaucuccg      420

agaccagcac caucauccgc gggcgguggu gcggccacaa ggaggugccc ccgcgcauca      480

agucccggac caaccagauc aagaucaccu ucaagagcga cgacuacuuc gucgccaagc      540

ccggguucaa gaucuacuac ucccugcugg aggacuucca gcccgcggcc gccagcgaga      600

cgaacuggga guccgugacc agcuccauca gcggcguguc cuacaacagc cccuccguca      660

ccgacccgac ccucaucgcc gacgcgcugg acaagaagau cgccgaguuc gacacggugg      720

aggaccugcu caaguacuuc aaccccgaga gcuggcagga ggaccuggag aacauguacc      780

uggacacccc gcgcuaccgg ggccgcagcu accacgaccg gaaguccaag guggaccucg      840

accgccugaa cgacgacgcc aagcgguaca gcugcacgcc ccgcaacuac uccgucaaca      900

uccgcgagga gcugaagcuc gccaacgugg uguucuuccc ccggugccug cugguccagc      960

gcugcggggg caacugcggg ugcggcaccg ugaacuggcg gagcugcacg ugcaacuccg     1020

ggaagaccgu gaagaaguac cacgaggucc uccaguucga gcccggccac aucaagcgcc     1080

ggggccgcgc caagaccaug gcgcuggugg acauccagcu ggaccaccac gagcggugcg     1140

acugcaucug cagcucccgc ccgccccggu gaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  3984
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt1)

<400>  3984
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugacccaca gcaaguuccc cgccgccggc augucccgcc      120

cgcuggacac cagccuccgg cugaagacgu ucuccagcaa guccgaguac cagcuggucg      180

ugaacgcggu gcgcaagcuc caggagagcg gguucuacug guccgccguc accggcgggg      240

aggccaaccu gcugcucagc gccgagcccg ccggcaccuu ccugauccgg gacuccagcg      300

accagcgcca cuucuucacc cuguccguga agacgcagag cgggaccaag aaccuccgga      360

uccagugcga gggcggcucc uucagccugc aguccgaccc ccgcagcacc cagcccgugc      420

cgcgguucga cugcguccug aagcucgugc accacuacau gcccccgccc ggggcgcccu      480

ccuuccccag cccgcccacc gagcccucca gcgaggugcc cgagcagccc agcgcccagc      540

cccugccggg cuccccgccc cgccgggccu acuacaucua cagcgggggc gagaagaucc      600

cccugguccu cucccgcccc cugagcucca acguggccac gcugcagcac cucugccgga      660

agaccgugaa cgggcaccug gacagcuacg agaaggucac ccagcugccc ggccccaucc      720

gcgaguuccu cgaccaguac gacgcgcccc ugugaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  3985
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt1)

<400>  3985
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugcccagcg ccggccagcu ggcccucuuc gcgcugggga      120

ucguccuggc cgccugccag gcccucgaga acuccaccag cccgcugucc gccgacccgc      180

ccguggcggc cgccgugguc agccacuuca acgacugccc cgacucccac acccaguucu      240

gcuuccacgg cacgugccgc uuccuggugc aggaggacaa gcccgccugc gugugccaca      300

gcggguacgu cggcgcgcgg ugcgagcacg ccgaccuccu ggccguggug gccgccuccc      360

agaagaagca ggcgaucacc gcccuggucg uggugagcau cgucgcccuc gccgugcuga      420

ucaucacgug cgugcugauc cacugcugcc agguccgcaa gcacugcgag uggugccggg      480

cccucaucug ccgccacgag aagcccuccg cgcugcugaa ggggcggacc gccugcugcc      540

acagcgagac cgugguguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  3986
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt1)

<400>  3986
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccccgagcg gccugcgccu ccugccccug cuccugcccc      120

ugcucuggcu gcuggugcuc acccccgggc ggccggccgc cggccugucc acgugcaaga      180

ccaucgacau ggagcugguc aagcgcaagc ggaucgaggc gauccgcggg cagauccuca      240

gcaagcugcg gcuggccucc ccgcccagcc agggcgaggu gccgcccggg ccccuccccg      300

aggccgugcu ggcccuguac aacuccaccc gcgaccgggu cgccggcgag agcgcggagc      360

ccgagcccga gcccgaggcc gacuacuacg ccaaggaggu gacccgcgug cucauggucg      420

agacccacaa cgagaucuac gacaaguuca agcaguccac gcacagcauc uacauguucu      480

ucaacaccuc cgagcugcgg gaggccgugc ccgagcccgu gcugcucagc cgcgcggagc      540

ugcggcugcu ccgccugaag cugaaggucg agcagcacgu ggagcucuac cagaaguacu      600

ccaacaacag cuggcgguac cuguccaacc gccugcucgc cccgagcgac ucccccgagu      660

ggcugagcuu cgacgugacc ggcgucgugc ggcaguggcu gucccgcggg ggcgagaucg      720

agggguuccg gcucagcgcc cacugcuccu gcgacagccg cgacaacacc cuccaggugg      780

acaucaacgg cuucacgacc gggcggcgcg gcgaccuggc caccauccac ggcaugaacc      840

ggcccuuccu gcugcugaug gccacgcccc ucgagcgcgc gcagcaccuc cagagcuccc      900

gccaccggcg cgcccuggac accaacuacu gcuucagcuc caccgagaag aacugcugcg      960

uccggcagcu guacaucgac uuccgcaagg accuggggug gaaguggauc cacgagccga     1020

agggcuacca cgccaacuuc ugccuggggc ccugccccua caucuggagc cucgacaccc     1080

aguacuccaa ggugcuggcc cuguacaacc agcacaaccc cggcgccagc gcggccccgu     1140

gcugcgugcc ccaggcccuc gagccccugc ccaucgucua cuacgugggc cggaagccga     1200

agguggagca gcuguccaac augaucgucc gcagcugcaa gugcuccuga ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  3987
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt1)

<400>  3987
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg ugcugagcgc cuuccucauc cugcaccugg      120

ucaccguggc ccucucccug agcacgugcu ccacccugga cauggaccag uucaugcgca      180

agcggaucga ggcgauccgc ggccagaucc ucagcaagcu gaagcugacc agcccgcccg      240

aggacuaccc cgagcccgag gaggugcccc cggaggucau cuccaucuac aacuccaccc      300

gggaccuccu gcaggagaag gccagccgcc gggccgccgc cugcgagcgc gagcgguccg      360

acgaggagua cuacgcgaag gagguguaca agaucgacau gccgcccuuc uuccccagcg      420

agaacgccau cccgcccacc uucuaccgcc ccuacuuccg gaucgugcgc uucgacgucu      480

ccgccaugga gaagaacgcc agcaaccugg ugaaggcgga guuccgggug uuccgccucc      540

agaaccccaa ggcccggguc cccgagcagc gcaucgagcu guaccagauc cugaagucca      600

aggaccucac gagccccacc cagcgguaca ucgacuccaa gguggugaag acccgcgccg      660

agggggagug gcugagcuuc gacgucaccg acgccgugca cgaguggcug caccacaagg      720

accggaaccu cggcuucaag aucucccugc acugccccug cugcacguuc gugcccagca      780

acaacuacau caucccgaac aaguccgagg agcuggaggc ccgcuucgcg gggaucgacg      840

gcaccagcac cuacaccagc ggggaccaga agacgaucaa guccacccgg aagaagaaca      900

gcggcaagac gccccaccuc cugcugaugc uccugcccuc cuaccgccug gagagccagc      960

agaccaaccg gcgcaagaag cgcgcccucg acgccgccua cugcuuccgg aacguccagg     1020

acaacugcug ccugcgcccc cuguacaucg acuucaagcg ggaccucggc uggaagugga     1080

uccacgagcc gaagggguac aacgccaacu ucugcgcggg cgccugcccc uaccuguggu     1140

ccagcgacac ccagcacucc cgcgugcuga gccucuacaa caccaucaac cccgaggccu     1200

ccgccagccc cugcugcgug ucccaggacc uggagccgcu gaccauccuc uacuacaucg     1260

ggaagacccc caagaucgag cagcugagca acaugaucgu caaguccugc aagugcagcu     1320

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  3988
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt1)

<400>  3988
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacc uccagcgcgc ccucguggug cuggcccugc      120

ucaacuucgc gaccgugagc cugucccuga gcacgugcac cacccucgac uucggccaca      180

ucaagaagaa gcggguggag gccauccgcg ggcagauccu guccaagcug cggcucacca      240

gcccgcccga gcccaccguc augacgcacg ugcccuacca ggugcuggcc cuguacaacu      300

ccacccgcga gcuccuggag gagaugcacg gcgagcggga ggaggggugc acccaggaga      360

acaccgagag cgaguacuac gccaaggaga uccacaaguu cgacaugauc cagggccugg      420

ccgagcacaa cgagcucgcg gucugcccca aggggaucac guccaaggug uuccgcuuca      480

acgugagcuc cgucgagaag aaccggacca accuguuccg cgccgaguuc cgggugcugc      540

gcgugccgaa ccccagcucc aagcggaacg agcagcgcau cgagcuguuc cagauccugc      600

ggcccgacga gcacaucgcc aagcagcgcu acaucggcgg caagaaccug cccacccggg      660

ggaccgccga guggcucagc uucgacguca cggacaccgu gcgcgagugg cugcugcggc      720

gcgaguccaa ccucggccug gagaucagca uccacugccc gugccacacc uuccagccca      780

acggggacau ccuggagaac auccacgagg ugauggagau caaguucaag ggcgucgaca      840

acgaggacga ccacgggcgg ggcgaccucg gccgccugaa gaagcagaag gaccaccaca      900

acccccaccu gauccucaug augaucccgc cccaccggcu ggacaacccc gggcagggcg      960

ggcagcgcaa gaagcgcgcg cuggacacca acuacugcuu ccggaaccuc gaggagaacu     1020

gcugcgugcg cccccuguac aucgacuucc ggcaggaccu gggcuggaag ugggugcacg     1080

agcccaaggg cuacuacgcc aacuucugcu ccgggccgug ccccuaccuc cgcagcgccg     1140

acacgaccca cuccaccguc cugggccugu acaacacccu caaccccgag gccagcgccu     1200

cccccugcug cgugccgcag gaccuggagc cccugacgau ccucuacuac guggggcgga     1260

cccccaaggu cgagcagcug agcaacaugg uggucaagag cugcaagugc uccugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  3989
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt1)

<400>  3989
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccccgugg ccgucugggc ggcccuggcc gugggccucg      120

agcugugggc cgccgcgcac gcccugccgg cccagguggc cuucaccccc uacgcgcccg      180

agcccgggag cacgugccgc cuccgggagu acuacgacca gaccgcccag augugcugcu      240

ccaagugcag cccgggccag cacgccaagg ucuucugcac caagaccucc gacaccgugu      300

gcgacagcug cgaggacucc acguacaccc agcuguggaa cugggugccc gagugccuga      360

gcugcggguc ccgcugcagc uccgaccagg ucgagaccca ggccugcacc cgggagcaga      420

accgcaucug cacgugccgg cccggcuggu acugcgcccu cagcaagcag gaggggugcc      480

gccugugcgc gccccugcgg aagugccgcc cgggcuucgg cguggcccgg cccgggaccg      540

agaccuccga cguggucugc aagcccugcg cccccggcac cuucagcaac acgaccucca      600

gcaccgacau cugccgcccg caccagaucu gcaacguggu ggccaucccc gggaacgccu      660

ccauggacgc ggucugcacc agcacguccc ccacccggag cauggccccc ggcgccgugc      720

accucccgca gcccgugucc acccgcagcc agcacaccca gcccacgccc gagccgagca      780

ccgcccccuc caccagcuuc cugcugccca uggggcccuc cccgcccgcc gagggcagca      840

ccggcgacuu cgcgcucccc gucgggcuga ucgugggcgu gacggcccug gggcuccuga      900

ucaucggcgu cgugaacugc gugaucauga cccaggucaa gaagaagccc cugugccucc      960

agcgggaggc caaggugccg caccuccccg ccgacaaggc ccgcggcacc caggggcccg     1020

agcagcagca ccuccugauc accgcgccgu ccagcuccag cuccagccug gaguccagcg     1080

ccuccgcccu ggaccggcgc gcccccacgc ggaaccagcc ccaggcgccc ggcguggagg     1140

ccagcggggc cggcgaggcc cgcgccucca ccgggagcuc cgacagcucc ccgggcggcc     1200

acgggaccca ggucaacgug accugcaucg ucaacgugug cagcagcucc gaccacagcu     1260

cccagugcag cucccaggcg agcuccacga ugggcgacac cgacagcucc cccagcgagu     1320

cccccaagga cgagcagguc cccuucagca aggaggagug cgccuuccgg ucccagcugg     1380

agaccccgga gacccugcug gggagcacgg aggagaagcc ccucccccug ggcgugcccg     1440

acgccgggau gaagccgucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  3990
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt1)

<400>  3990
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgugaugc gccuguuccc gugcuuccuc cagcugcugg      120

ccggccucgc ccugcccgcg gucccgcccc agcagugggc ccugagcgcc gggaacggcu      180

ccagcgaggu ggaggugguc cccuuccagg aggugugggg gcgguccuac ugccgcgccc      240

ucgagcggcu gguggacguc gugagcgagu accccuccga gguggagcac auguucagcc      300

ccuccugcgu cagccugcuc cgcugcaccg gcugcugcgg ggacgagaac cugcacugcg      360

ugcccgugga gaccgccaac gucacgaugc agcugcucaa gauccggucc ggcgaccgcc      420

cgagcuacgu ggagcugacc uucucccagc acgugcggug cgagugccgc ccccugcggg      480

agaagaugaa gcccgagcgc cggcgcccca agggccgggg gaagcgccgg cgcgagaagc      540

agcggccgac cgacugccac cucugcggcg acgcgguccc ccgccgguga ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  3991
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt1)

<400>  3991
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgaccgcc agaccgacac ggcccccagc ccguccuacc      120

accuccugcc cggccggcgc cggaccgugg acgccgcggc cagccgcggg cagggccccg      180

agcccgcccc cgggggcggg gucgagggcg ugggcgcccg cgggguggcc cugaagcugu      240

ucguccagcu ccugggcugc ucccgguucg ggggcgcggu ggugcgggcc ggggaggccg      300

agcccagcgg cgccgcgcgc uccgccagcu ccggccggga ggagccccag cccgaggagg      360

gggaggagga ggaggagaag gaggaggagc gcggcccgca guggcggcug ggggcccgca      420

agcccggcag cuggaccggc gaggccgccg ucugcgcgga cuccgccccc gccgcccggg      480

ccccgcaggc gcucgcccgc gccagcgggc ggggcgggcg cguggcccgg cgcggcgccg      540

aggaguccgg gccgccccac agccccuccc ggcgcggcag cgcgucccgg gccggccccg      600

ggcgcgccag cgagaccaug aacuuccugc uguccugggu gcacuggagc cucgcccugc      660

ugcucuaccu gcaccacgcc aagugguccc aggcggcccc gauggccgag ggcgggggcc      720

agaaccacca cgaggucgug aaguucaugg acguguacca gcgcagcuac ugccacccca      780

ucgagacgcu ggucgacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      840

ccagcugcgu gccgcucaug cggugcgggg gcugcugcaa cgacgagggc cuggagugcg      900

ugcccaccga ggaguccaac aucaccaugc agaucaugcg caucaagccc caccaggggc      960

agcacaucgg cgagaugagc uuccugcagc acaacaagug cgagugccgg cccaagaagg     1020

accgcgcccg gcaggagaag aaguccgucc gcgggaaggg caaggggcag aagcggaagc     1080

gcaagaaguc ccgguacaag agcuggagcg uguacguggg cgcgcgcugc ugccucaugc     1140

cguggucccu gcccggcccc caccccugcg ggccgugcag cgagcggcgc aagcaccugu     1200

ucguccagga cccccagacc ugcaagugcu ccugcaagaa cacggacagc cggugcaagg     1260

cccgccagcu cgagcugaac gagcggaccu gccgcugcga caagccccgg cgcugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  3992
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt1)

<400>  3992
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggucc cuggcccugc      120

uccuguaccu gcaccacgcc aaguggagcc aggcggcccc cauggccgag ggcgggggcc      180

agaaccacca cgaggucgug aaguucaugg acguguacca gcgcuccuac ugccacccga      240

ucgagacccu cgucgacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      300

ccagcugcgu gccccugaug cggugcgggg gcugcugcaa cgacgagggg cuggagugcg      360

ugccgaccga ggaguccaac aucacgaugc agaucaugcg caucaagccc caccagggcc      420

agcacaucgg cgagaugagc uuccuccagc acaacaagug cgagugccgg cccaagaagg      480

accgcgcccg gcaggagaag aaguccgucc gcgggaaggg caaggggcag aagcggaagc      540

gcaagaaguc ccgguacaag agcuggagcg uguacguggg cgcccgcugc ugccugaugc      600

ccuggucccu gccggggccc caccccugcg gccccugcag cgagcggcgc aagcaccucu      660

ucguccagga cccgcagacc ugcaagugcu ccugcaagaa caccgacagc cggugcaagg      720

cgcgccagcu ggagcugaac gagcggaccu gccgcugcga caagccccgg cgcugaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  3993
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt1)

<400>  3993
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcccccugc uccgccggcu gcugcucgcc gcccugcugc      120

agcucgcgcc ggcccaggcc cccguguccc agcccgacgc ccccggccac cagcgcaagg      180

ucgugagcug gaucgacgug uacacccggg cgaccugcca gccgcgcgag gucguggugc      240

cccugacggu cgagcugaug gggaccgugg ccaagcagcu cgugcccucc ugcgucaccg      300

ugcagcggug cggcgggugc ugccccgacg acggccugga gugcgugccg accgggcagc      360

accagguccg caugcagauc cugaugaucc gguaccccag cucccagcuc ggcgagauga      420

gccuggagga gcacucccag ugcgagugcc gccccaagaa gaaggacagc gccgugaagc      480

ccgaccgggc cgccacgccg caccaccgcc cccagccccg guccgugccc ggcugggaca      540

gcgcgccggg ggcccccucc cccgccgaca ucacccaccc caccccggcc cccggcccca      600

gcgcccacgc ggcccccucc accacgagcg cccugacccc ggggcccgcc gccgcggccg      660

ccgacgccgc cgcguccagc gucgccaagg gcggggccug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  3994
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt1)

<400>  3994
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuccugg gcuucuucag cguggccugc ucccugcugg      120

ccgcggcccu ccugcccggg ccgcgcgagg cccccgccgc cgcggccgcc uucgagagcg      180

gccuggaccu cuccgacgcc gagcccgacg cgggggaggc caccgccuac gccagcaagg      240

accuggagga gcagcugcgg uccgucagcu ccguggacga gcucaugacc gugcuguacc      300

ccgaguacug gaagauguac aagugccagc ugcgcaaggg cggguggcag cacaaccggg      360

agcaggccaa ccucaacagc cgcacggagg agaccaucaa guucgcggcc gcccacuaca      420

acaccgagau ccugaagucc aucgacaacg aguggcggaa gacccagugc augccgcgcg      480

aggucugcau cgacgugggc aaggaguucg gcguggccac gaacaccuuc uucaagccgc      540

ccugcgucag cguguaccgg ugcgggggcu gcugcaacuc cgaggggcug cagugcauga      600

acaccagcac cuccuaccuc agcaagacgc uguucgagau caccgugccc cugucccagg      660

gccccaagcc cgucaccauc agcuucgcca accacaccuc cugccgcugc augagcaagc      720

ucgacgugua ccgccaggug cacuccauca uccggcggag ccugcccgcg acgcugcccc      780

agugccaggc cgccaacaag accugcccga ccaacuacau guggaacaac cacaucugcc      840

gcugccucgc ccaggaggac uucauguuca gcuccgacgc cggggacgac agcaccgacg      900

gcuuccacga caucugcggc cccaacaagg agcuggacga ggagacgugc cagugcgucu      960

gccgggcggg gcugcgcccc gccuccugcg gcccccacaa ggagcucgac cggaacagcu     1020

gccagugcgu gugcaagaac aagcuguucc cgucccagug cggggccaac cgcgaguucg     1080

acgagaacac gugccagugc gugugcaagc ggaccugccc ccgcaaccag ccccugaacc     1140

ccggcaagug cgccugcgag ugcaccgaga gcccgcagaa gugccuccug aagggcaaga     1200

aguuccacca ccagaccugc uccugcuacc ggcgccccug caccaaccgg cagaaggccu     1260

gcgagcccgg guucagcuac uccgaggagg ucugccgcug cgugcccagc uacuggaagc     1320

gcccgcagau guccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  3995
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt1)

<400>  3995
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uaccgcgagu ggguggucgu gaacguguuc augaugcugu      120

acguccagcu cgugcagggc agcuccaacg agcacgggcc cgugaagcgg agcucccaga      180

gcacccugga gcgcuccgag cagcagaucc gggccgccag cucccuggag gagcuccugc      240

gcaucaccca cagcgaggac uggaagcugu ggcggugccg ccuccggcug aaguccuuca      300

cgagcaugga cucccgcagc gcgucccacc ggagcacccg cuucgccgcc accuucuacg      360

acaucgagac ccugaagguc aucgacgagg aguggcagcg gacgcagugc uccccgcgcg      420

agaccugcgu ggagguggcc agcgagcucg gcaaguccac caacaccuuc uucaagccgc      480

ccugcgucaa cguguuccgg ugcgggggcu gcugcaacga ggagagccug aucugcauga      540

acacguccac cagcuacauc agcaagcagc uguucgagau cuccgugccc cucaccagcg      600

uccccgagcu ggugcccgug aaggucgcca accacaccgg gugcaagugc cugcccacgg      660

cgccccgcca cccguacucc aucauccggc gcagcaucca gauccccgag gaggaccggu      720

gcucccacag caagaagcuc ugccccaucg acaugcugug ggacuccaac aagugcaagu      780

gcgugcugca ggaggagaac ccccucgccg gcaccgagga ccacagccac cuccaggagc      840

cggcccugug cggcccccac augauguucg acgaggaccg cugcgagugc gugugcaaga      900

cccccugccc caaggaccug auccagcacc cgaagaacug cuccugcuuc gagugcaagg      960

agagccugga gaccugcugc cagaagcaca agcuguucca ccccgacacg ugcuccugcg     1020

aggaccggug ccccuuccac acccgccccu gcgccagcgg gaagaccgcg ugcgccaagc     1080

acugccgguu cccgaaggag aagcgcgccg cccagggccc ccacucccgc aagaaccccu     1140

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  3996
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt2)

<400>  3996
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg agaccggcuu cgagcacucc ggccucuggg      120

ucuccguccu cgccggccuc cuccucggcg ccugccaggc ccaccccauc cccgacuccu      180

ccccccuccu ccaguucggc ggccaggucc gccagcgcua ccucuacacc gacgacgccc      240

agcagaccga ggcccaccuc gagauccgcg aggacggcac cgucggcggc gccgccgacc      300

agucccccga gucccuccuc cagcucaagg cccucaagcc cggcgucauc cagauccucg      360

gcgucaagac cucccgcuuc cucugccagc gccccgacgg cgcccucuac ggcucccucc      420

acuucgaccc cgaggccugc uccuuccgcg agcuccuccu cgaggacggc uacaacgucu      480

accaguccga ggcccacggc cucccccucc accuccccgg caacaagucc ccccaccgcg      540

accccgcccc ccgcggcccc gcccgcuucc ucccccuccc cggccucccc cccgcccucc      600

ccgagccccc cggcauccuc gccccccagc cccccgacgu cggcuccucc gacccccucu      660

ccauggucgg ccccucccag ggccgcuccc ccuccuacgc cuccugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  3997
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt2)

<400>  3997
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuccuucc ccccccuccu ccuccuccuc uucuggggcg      120

ucgucuccca cuccuucccc gccacccucg agacccagga gcaggacguc gaccucgucc      180

agaaguaccu cgagaaguac uacaaccuca agaacgacgg ccgccagguc gagaagcgcc      240

gcaacuccgg ccccgucguc gagaagcuca agcagaugca ggaguucuuc ggccucaagg      300

ucaccggcaa gcccgacgcc gagacccuca aggucaugaa gcagccccgc ugcggcgucc      360

ccgacgucgc ccaguucguc cucaccgagg gcaacccccg cugggagcag acccaccuca      420

ccuaccgcau cgagaacuac acccccgacc ucccccgcgc cgacgucgac cacgccaucg      480

agaaggccuu ccagcucugg uccaacguca ccccccucac cuucaccaag gucuccgagg      540

gccaggccga caucaugauc uccuucgucc gcggcgacca ccgcgacaac ucccccuucg      600

acggccccgg cggcaaccuc gcccacgccu uccagcccgg ccccggcauc ggcggcgacg      660

cccacuucga cgaggacgag cgcuggacca acaacuuccg cgaguacaac cuccaccgcg      720

ucgccgccca cgagcucggc cacucccucg gccucuccca cuccaccgac aucggcgccc      780

ucauguaccc cuccuacacc uucuccggcg acguccagcu cgcccaggac gacaucgacg      840

gcauccaggc caucuacggc cgcucccaga accccgucca gcccaucggc ccccagaccc      900

ccaaggccug cgacuccaag cucaccuucg acgccaucac caccauccgc ggcgagguca      960

uguucuucaa ggaccgcuuc uacaugcgca ccaaccccuu cuaccccgag gucgagcuca     1020

acuucaucuc cgucuucugg ccccagcucc ccaacggccu cgaggccgcc uacgaguucg     1080

ccgaccgcga cgagguccgc uucuucaagg gcaacaagua cugggccguc cagggccaga     1140

acguccucca cggcuacccc aaggacaucu acuccuccuu cggcuucccc cgcaccguca     1200

agcacaucga cgccgcccuc uccgaggaga acaccggcaa gaccuacuuc uucgucgcca     1260

acaaguacug gcgcuacgac gaguacaagc gcuccaugga ccccggcuac cccaagauga     1320

ucgcccacga cuuccccggc aucggccaca aggucgacgc cgucuucaug aaggacggcu     1380

ucuucuacuu cuuccacggc acccgccagu acaaguucga ccccaagacc aagcgcaucc     1440

ucacccucca gaaggccaac uccugguuca acugccgcaa gaacugagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  3998
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt2)

<400>  3998
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuccuucc ccccccuccu ccuccuccuc uucuggggcg      120

ucgucuccca cuccuucguc cucaccgagg gcaacccccg cugggagcag acccaccuca      180

ccuaccgcau cgagaacuac acccccgacc ucccccgcgc cgacgucgac cacgccaucg      240

agaaggccuu ccagcucugg uccaacguca ccccccucac cuucaccaag gucuccgagg      300

gccaggccga caucaugauc uccuucgucc gcggcgacca ccgcgacaac ucccccuucg      360

acggccccgg cggcaaccuc gcccacgccu uccagcccgg ccccggcauc ggcggcgacg      420

cccacuucga cgaggacgag cgcuggacca acaacuuccg cgaguacaac cuccaccgcg      480

ucgccgccca cgagcucggc cacucccucg gccucuccca cuccaccgac aucggcgccc      540

ucauguaccc cuccuacacc uucuccggcg acguccagcu cgcccaggac gacaucgacg      600

gcauccaggc caucuacggc cgcucccaga accccgucca gcccaucggc ccccagaccc      660

ccaaggccug cgacuccaag cucaccuucg acgccaucac caccauccgc ggcgagguca      720

uguucuucaa ggaccgcuuc uacaugcgca ccaaccccuu cuaccccgag gucgagcuca      780

acuucaucuc cgucuucugg ccccagcucc ccaacggccu cgaggccgcc uacgaguucg      840

ccgaccgcga cgagguccgc uucuucaagg gcaacaagua cugggccguc cagggccaga      900

acguccucca cggcuacccc aaggacaucu acuccuccuu cggcuucccc cgcaccguca      960

agcacaucga cgccgcccuc uccgaggaga acaccggcaa gaccuacuuc uucgucgcca     1020

acaaguacug gcgcuacgac gaguacaagc gcuccaugga ccccggcuac cccaagauga     1080

ucgcccacga cuuccccggc aucggccaca aggucgacgc cgucuucaug aaggacggcu     1140

ucuucuacuu cuuccacggc acccgccagu acaaguucga ccccaagacc aagcgcaucc     1200

ucacccucca gaaggccaac uccugguuca acugccgcaa gaacugagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  3999
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt2)

<400>  3999
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaagaaca uccucaagau ccucauggac uccuacucca      120

aggaguccaa gauccagacc guccgccgcg ucaccuccgu cucccuccuc gccgucuacc      180

ucaccaugaa caccuccucc cucguccucg ccaagcccau cgagaacacc aacgacaccu      240

ccaucaagaa cgucgagaag cuccgcaacg cccccaacga ggagaacucc aagaaggucg      300

aggacuccaa gaacgacaag gucgagcacg ucaagaacau cgaggaggcc aaggucgagc      360

aggucgcccc cgaggucaag uccaagucca cccuccgcuc cgccuccauc gccaacacca      420

acuccgagaa guacgacuuc gaguaccuca acggccucuc cuacaccgag cucaccaacc      480

ucaucaagaa caucaagugg aaccagauca acggccucuu caacuacucc accggcuccc      540

agaaguucuu cggcgacaag aaccgcgucc aggccaucau caacgcccuc caggaguccg      600

gccgcaccua caccgccaac gacaugaagg gcaucgagac cuucaccgag guccuccgcg      660

ccggcuucua ccucggcuac uacaacgacg gccucuccua ccucaacgac cgcaacuucc      720

aggacaagug cauccccgcc augaucgcca uccagaagaa ccccaacuuc aagcucggca      780

ccgccgucca ggacgagguc aucaccuccc ucggcaagcu caucggcaac gccuccgcca      840

acgccgaggu cgucaacaac ugcguccccg uccucaagca guuccgcgag aaccucaacc      900

aguacgcccc cgacuacguc aagggcaccg ccgucaacga gcucaucaag ggcaucgagu      960

ucgacuucuc cggcgccgcc uacgagaagg acgucaagac caugcccugg uacggcaaga     1020

ucgaccccuu caucaacgag cucaaggccc ucggccucua cggcaacauc accuccgcca     1080

ccgagugggc cuccgacguc ggcaucuacu accucuccaa guucggccuc uacuccacca     1140

accgcaacga caucguccag ucccucgaga aggccgucga cauguacaag uacggcaaga     1200

ucgccuucgu cgccauggag cgcaucaccu gggacuacga cggcaucggc uccaacggca     1260

agaaggucga ccacgacaag uuccucgacg acgccgagaa gcacuaccuc cccaagaccu     1320

acaccuucga caacggcacc uucaucaucc gcgccggcga caaggucucc gaggagaaga     1380

ucaagcgccu cuacugggcc ucccgcgagg ucaaguccca guuccaccgc gucgucggca     1440

acgacaaggc ccucgagguc ggcaacgccg acgacguccu caccaugaag aucuucaacu     1500

cccccgagga guacaaguuc aacaccaaca ucaacggcgu cuccaccgac aacggcggcc     1560

ucuacaucga gccccgcggc accuucuaca ccuacgagcg caccccccag caguccaucu     1620

ucucccucga ggagcucuuc cgccacgagu acacccacua ccuccaggcc cgcuaccucg     1680

ucgacggccu cuggggccag ggccccuucu acgagaagaa ccgccucacc ugguucgacg     1740

agggcaccgc cgaguucuuc gccggcucca cccgcaccuc cggcguccuc ccccgcaagu     1800

ccauccucgg cuaccucgcc aaggacaagg ucgaccaccg cuacucccuc aagaagaccc     1860

ucaacuccgg cuacgacgac uccgacugga uguucuacaa cuacggcuuc gccgucgccc     1920

acuaccucua cgagaaggac augcccaccu ucaucaagau gaacaaggcc auccucaaca     1980

ccgacgucaa guccuacgac gagaucauca agaagcucuc cgacgacgcc aacaagaaca     2040

ccgaguacca gaaccacauc caggagcucg ccgacaagua ccagggcgcc ggcauccccc     2100

ucgucuccga cgacuaccuc aaggaccacg gcuacaagaa ggccuccgag gucuacuccg     2160

agaucuccaa ggccgccucc cucaccaaca ccuccgucac cgccgagaag ucccaguacu     2220

ucaacaccuu cacccuccgc ggcaccuaca ccggcgagac cuccaagggc gaguucaagg     2280

acugggacga gauguccaag aagcucgacg gcacccucga gucccucgcc aagaacuccu     2340

gguccggcua caagacccuc accgccuacu ucaccaacua ccgcgucacc uccgacaaca     2400

agguccagua cgacgucguc uuccacggcg uccucaccga caacgccgac aucuccaaca     2460

acaaggcccc caucgccaag gucaccggcc ccuccaccgg cgccgucggc cgcaacaucg     2520

aguucuccgg caaggacucc aaggacgagg acggcaagau cgucuccuac gacugggacu     2580

ucggcgacgg cgccaccucc cgcggcaaga acuccgucca cgccuacaag aaggccggca     2640

ccuacaacgu cacccucaag gucaccgacg acaagggcgc caccgccacc gaguccuuca     2700

ccaucgagau caagaacgag gacaccacca cccccaucac caaggagaug gagcccaacg     2760

acgacaucaa ggaggccaac ggccccaucg ucgagggcgu caccgucaag ggcgaccuca     2820

acggcuccga cgacgccgac accuucuacu ucgacgucaa ggaggacggc gacgucacca     2880

ucgagcuccc cuacuccggc uccuccaacu ucaccuggcu cgucuacaag gagggcgacg     2940

accagaacca caucgccucc ggcaucgaca agaacaacuc caaggucggc accuucaagu     3000

ccaccaaggg ccgccacuac gucuucaucu acaagcacga cuccgccucc aacaucuccu     3060

acucccucaa caucaagggc cucggcaacg agaagcucaa ggagaaggag aacaacgacu     3120

ccuccgacaa ggccaccguc auccccaacu ucaacaccac caugcagggc ucccuccucg     3180

gcgacgacuc ccgcgacuac uacuccuucg aggucaagga ggagggcgag gucaacaucg     3240

agcucgacaa gaaggacgag uucggcguca ccuggacccu ccaccccgag uccaacauca     3300

acgaccgcau caccuacggc caggucgacg gcaacaaggu cuccaacaag gucaagcucc     3360

gccccggcaa guacuaccuc cucgucuaca aguacuccgg cuccggcaac uacgagcucc     3420

gcgucaacaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  4000
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt2)

<400>  4000
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguca ccuucaucuc ccuccucuuc cucuucuccu      120

ccgccuacuc caucgccaac accaacuccg agaaguacga cuucgaguac cucaacggcc      180

ucuccuacac cgagcucacc aaccucauca agaacaucaa guggaaccag aucaacggcc      240

ucuucaacua cuccaccggc ucccagaagu ucuucggcga caagaaccgc guccaggcca      300

ucaucaacgc ccuccaggag uccggccgca ccuacaccgc caacgacaug aagggcaucg      360

agaccuucac cgagguccuc cgcgccggcu ucuaccucgg cuacuacaac gacggccucu      420

ccuaccucaa cgaccgcaac uuccaggaca agugcauccc cgccaugauc gccauccaga      480

agaaccccaa cuucaagcuc ggcaccgccg uccaggacga ggucaucacc ucccucggca      540

agcucaucgg caacgccucc gccaacgccg aggucgucaa caacugcguc cccguccuca      600

agcaguuccg cgagaaccuc aaccaguacg cccccgacua cgucaagggc accgccguca      660

acgagcucau caagggcauc gaguucgacu ucuccggcgc cgccuacgag aaggacguca      720

agaccaugcc cugguacggc aagaucgacc ccuucaucaa cgagcucaag gcccucggcc      780

ucuacggcaa caucaccucc gccaccgagu gggccuccga cgucggcauc uacuaccucu      840

ccaaguucgg ccucuacucc accaaccgca acgacaucgu ccagucccuc gagaaggccg      900

ucgacaugua caaguacggc aagaucgccu ucgucgccau ggagcgcauc accugggacu      960

acgacggcau cggcuccaac ggcaagaagg ucgaccacga caaguuccuc gacgacgccg     1020

agaagcacua ccuccccaag accuacaccu ucgacaacgg caccuucauc auccgcgccg     1080

gcgacaaggu cuccgaggag aagaucaagc gccucuacug ggccucccgc gaggucaagu     1140

cccaguucca ccgcgucguc ggcaacgaca aggcccucga ggucggcaac gccgacgacg     1200

uccucaccau gaagaucuuc aacucccccg aggaguacaa guucaacacc aacaucaacg     1260

gcgucuccac cgacaacggc ggccucuaca ucgagccccg cggcaccuuc uacaccuacg     1320

agcgcacccc ccagcagucc aucuucuccc ucgaggagcu cuuccgccac gaguacaccc     1380

acuaccucca ggcccgcuac cucgucgacg gccucugggg ccagggcccc uucuacgaga     1440

agaaccgccu caccugguuc gacgagggca ccgccgaguu cuucgccggc uccacccgca     1500

ccuccggcgu ccucccccgc aaguccaucc ucggcuaccu cgccaaggac aaggucgacc     1560

accgcuacuc ccucaagaag acccucaacu ccggcuacga cgacuccgac uggauguucu     1620

acaacuacgg cuucgccguc gcccacuacc ucuacgagaa ggacaugccc accuucauca     1680

agaugaacaa ggccauccuc aacaccgacg ucaaguccua cgacgagauc aucaagaagc     1740

ucuccgacga cgccaacaag aacaccgagu accagaacca cauccaggag cucgccgaca     1800

aguaccaggg cgccggcauc ccccucgucu ccgacgacua ccucaaggac cacggcuaca     1860

agaaggccuc cgaggucuac uccgagaucu ccaaggccgc cucccucacc aacaccuccg     1920

ucaccgccga gaagucccag uacuucaaca ccuucacccu ccgcggcacc uacaccggcg     1980

agaccuccaa gggcgaguuc aaggacuggg acgagauguc caagaagcuc gacggcaccc     2040

ucgagucccu cgccaagaac uccugguccg gcuacaagac ccucaccgcc uacuucacca     2100

acuaccgcgu caccuccgac aacaaggucc aguacgacgu cgucuuccac ggcguccuca     2160

ccgacaacgc cgacaucucc aacaacaagg cccccaucgc caaggucacc ggccccucca     2220

ccggcgccgu cggccgcaac aucgaguucu ccggcaagga cuccaaggac gaggacggca     2280

agaucgucuc cuacgacugg gacuucggcg acggcgccac cucccgcggc aagaacuccg     2340

uccacgccua caagaaggcc ggcaccuaca acgucacccu caaggucacc gacgacaagg     2400

gcgccaccgc caccgagucc uucaccaucg agaucaagaa cgaggacacc accaccccca     2460

ucaccaagga gauggagccc aacgacgaca ucaaggaggc caacggcccc aucgucgagg     2520

gcgucaccgu caagggcgac cucaacggcu ccgacgacgc cgacaccuuc uacuucgacg     2580

ucaaggagga cggcgacguc accaucgagc uccccuacuc cggcuccucc aacuucaccu     2640

ggcucgucua caaggagggc gacgaccaga accacaucgc cuccggcauc gacaagaaca     2700

acuccaaggu cggcaccuuc aaguccacca agggccgcca cuacgucuuc aucuacaagc     2760

acgacuccgc cuccaacauc uccuacuccc ucaacaucaa gggccucggc aacgagaagc     2820

ucaaggagaa ggagaacaac gacuccuccg acaaggccac cgucaucccc aacuucaaca     2880

ccaccaugca gggcucccuc cucggcgacg acucccgcga cuacuacucc uucgagguca     2940

aggaggaggg cgaggucaac aucgagcucg acaagaagga cgaguucggc gucaccugga     3000

cccuccaccc cgaguccaac aucaacgacc gcaucaccua cggccagguc gacggcaaca     3060

aggucuccaa caaggucaag cuccgccccg gcaaguacua ccuccucguc uacaaguacu     3120

ccggcuccgg caacuacgag cuccgcguca acaagugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  4001
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt2)

<400>  4001
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguca ccuucaucuc ccuccucuuc cucuucuccu      120

ccgccuacuc caugaagaag aacauccuca agauccucau ggacuccuac uccaaggagu      180

ccaagaucca gaccguccgc cgcgucaccu ccgucucccu ccucgccguc uaccucacca      240

ugaacaccuc cucccucguc cucgccaagc ccaucgagaa caccaacgac accuccauca      300

agaacgucga gaagcuccgc aacgccccca acgaggagaa cuccaagaag gucgaggacu      360

ccaagaacga caaggucgag cacgucaaga acaucgagga ggccaagguc gagcaggucg      420

cccccgaggu caaguccaag uccacccucc gcuccgccuc ccgccgccgc cgcaagcgca      480

ucgccaacac caacuccgag aaguacgacu ucgaguaccu caacggccuc uccuacaccg      540

agcucaccaa ccucaucaag aacaucaagu ggaaccagau caacggccuc uucaacuacu      600

ccaccggcuc ccagaaguuc uucggcgaca agaaccgcgu ccaggccauc aucaacgccc      660

uccaggaguc cggccgcacc uacaccgcca acgacaugaa gggcaucgag accuucaccg      720

agguccuccg cgccggcuuc uaccucggcu acuacaacga cggccucucc uaccucaacg      780

accgcaacuu ccaggacaag ugcauccccg ccaugaucgc cauccagaag aaccccaacu      840

ucaagcucgg caccgccguc caggacgagg ucaucaccuc ccucggcaag cucaucggca      900

acgccuccgc caacgccgag gucgucaaca acugcguccc cguccucaag caguuccgcg      960

agaaccucaa ccaguacgcc cccgacuacg ucaagggcac cgccgucaac gagcucauca     1020

agggcaucga guucgacuuc uccggcgccg ccuacgagaa ggacgucaag accaugcccu     1080

gguacggcaa gaucgacccc uucaucaacg agcucaaggc ccucggccuc uacggcaaca     1140

ucaccuccgc caccgagugg gccuccgacg ucggcaucua cuaccucucc aaguucggcc     1200

ucuacuccac caaccgcaac gacaucgucc agucccucga gaaggccguc gacauguaca     1260

aguacggcaa gaucgccuuc gucgccaugg agcgcaucac cugggacuac gacggcaucg     1320

gcuccaacgg caagaagguc gaccacgaca aguuccucga cgacgccgag aagcacuacc     1380

uccccaagac cuacaccuuc gacaacggca ccuucaucau ccgcgccggc gacaaggucu     1440

ccgaggagaa gaucaagcgc cucuacuggg ccucccgcga ggucaagucc caguuccacc     1500

gcgucgucgg caacgacaag gcccucgagg ucggcaacgc cgacgacguc cucaccauga     1560

agaucuucaa cucccccgag gaguacaagu ucaacaccaa caucaacggc gucuccaccg     1620

acaacggcgg ccucuacauc gagccccgcg gcaccuucua caccuacgag cgcacccccc     1680

agcaguccau cuucucccuc gaggagcucu uccgccacga guacacccac uaccuccagg     1740

cccgcuaccu cgucgacggc cucuggggcc agggccccuu cuacgagaag aaccgccuca     1800

ccugguucga cgagggcacc gccgaguucu ucgccggcuc cacccgcacc uccggcgucc     1860

ucccccgcaa guccauccuc ggcuaccucg ccaaggacaa ggucgaccac cgcuacuccc     1920

ucaagaagac ccucaacucc ggcuacgacg acuccgacug gauguucuac aacuacggcu     1980

ucgccgucgc ccacuaccuc uacgagaagg acaugcccac cuucaucaag augaacaagg     2040

ccauccucaa caccgacguc aaguccuacg acgagaucau caagaagcuc uccgacgacg     2100

ccaacaagaa caccgaguac cagaaccaca uccaggagcu cgccgacaag uaccagggcg     2160

ccggcauccc ccucgucucc gacgacuacc ucaaggacca cggcuacaag aaggccuccg     2220

aggucuacuc cgagaucucc aaggccgccu cccucaccaa caccuccguc accgccgaga     2280

agucccagua cuucaacacc uucacccucc gcggcaccua caccggcgag accuccaagg     2340

gcgaguucaa ggacugggac gagaugucca agaagcucga cggcacccuc gagucccucg     2400

ccaagaacuc cugguccggc uacaagaccc ucaccgccua cuucaccaac uaccgcguca     2460

ccuccgacaa caagguccag uacgacgucg ucuuccacgg cguccucacc gacaacgccg     2520

acaucuccaa caacaaggcc cccaucgcca aggucaccgg ccccuccacc ggcgccgucg     2580

gccgcaacau cgaguucucc ggcaaggacu ccaaggacga ggacggcaag aucgucuccu     2640

acgacuggga cuucggcgac ggcgccaccu cccgcggcaa gaacuccguc cacgccuaca     2700

agaaggccgg caccuacaac gucacccuca aggucaccga cgacaagggc gccaccgcca     2760

ccgaguccuu caccaucgag aucaagaacg aggacaccac cacccccauc accaaggaga     2820

uggagcccaa cgacgacauc aaggaggcca acggccccau cgucgagggc gucaccguca     2880

agggcgaccu caacggcucc gacgacgccg acaccuucua cuucgacguc aaggaggacg     2940

gcgacgucac caucgagcuc cccuacuccg gcuccuccaa cuucaccugg cucgucuaca     3000

aggagggcga cgaccagaac cacaucgccu ccggcaucga caagaacaac uccaaggucg     3060

gcaccuucaa guccaccaag ggccgccacu acgucuucau cuacaagcac gacuccgccu     3120

ccaacaucuc cuacucccuc aacaucaagg gccucggcaa cgagaagcuc aaggagaagg     3180

agaacaacga cuccuccgac aaggccaccg ucauccccaa cuucaacacc accaugcagg     3240

gcucccuccu cggcgacgac ucccgcgacu acuacuccuu cgaggucaag gaggagggcg     3300

aggucaacau cgagcucgac aagaaggacg aguucggcgu caccuggacc cuccaccccg     3360

aguccaacau caacgaccgc aucaccuacg gccaggucga cggcaacaag gucuccaaca     3420

aggucaagcu ccgccccggc aaguacuacc uccucgucua caaguacucc ggcuccggca     3480

acuacgagcu ccgcgucaac aagugaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  4002
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt2)

<400>  4002
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuca agaucauccu caaccgcggc aagaccauga      120

agcgcaagug ccucuccaag cgccucaugc ucgccaucac cauggccacc aucuucaccg      180

ucaacuccac ccuccccauc uacgccgccg ucgacaagaa caacgccacc gccgccgucc      240

agaacgaguc caagcgcuac accgucuccu accucaagac ccucaacuac uacgaccucg      300

ucgaccuccu cgucaagacc gagaucgaga accuccccga ccucuuccag uacuccuccg      360

acgccaagga guucuacggc aacaagaccc gcauguccuu caucauggac gagaucggcc      420

gccgcgcccc ccaguacacc gagaucgacc acaagggcau ccccacccuc gucgaggucg      480

uccgcgccgg cuucuaccuc ggcuuccaca acaaggagcu caacgagauc aacaagcgcu      540

ccuucaagga gcgcgucauc cccuccaucc ucgccaucca gaagaacccc aacuucaagc      600

ucggcaccga gguccaggac aagaucgucu ccgccaccgg ccuccucgcc ggcaacgaga      660

ccgccccccc cgaggucguc aacaacuuca cccccauccu ccaggacugc aucaagaaca      720

ucgaccgcua cgcccucgac gaccucaagu ccaaggcccu cuucaacguc cucgccgccc      780

ccaccuacga caucaccgag uaccuccgcg ccaccaagga gaagcccgag aacacccccu      840

gguacggcaa gaucgacggc uucaucaacg agcucaagaa gcucgcccuc uacggcaaga      900

ucaacgacaa caacuccugg aucaucgaca acggcaucua ccacaucgcc ccccucggca      960

agcuccacuc caacaacaag aucggcaucg agacccucac cgaggucaug aaggucuacc     1020

ccuaccucuc caugcagcac cuccaguccg ccgaccagau caagcgccac uacgacucca     1080

aggacgccga gggcaacaag aucccccucg acaaguucaa gaaggagggc aaggagaagu     1140

acugccccaa gaccuacacc uucgacgacg gcaaggucau caucaaggcc ggcgcccgcg     1200

ucgaggagga gaaggucaag cgccucuacu gggccuccaa ggaggucaac ucccaguucu     1260

uccgcgucua cggcaucgac aagccccucg aggagggcaa ccccgacgac auccucacca     1320

uggucaucua caacuccccc gaggaguaca agcucaacuc cguccucuac ggcuacgaca     1380

ccaacaacgg cggcauguac aucgagcccg agggcaccuu cuucaccuac gagcgcgagg     1440

cccaggaguc caccuacacc cucgaggagc ucuuccgcca cgaguacacc cacuaccucc     1500

agggccgcua cgccgucccc ggccaguggg gccgcaccaa gcucuacgac aacgaccgcc     1560

ucaccuggua cgaggagggc ggcgccgagc ucuucgccgg cuccacccgc accuccggca     1620

uccucccccg caaguccauc gucuccaaca uccacaacac cacccgcaac aaccgcuaca     1680

agcucuccga caccguccac uccaaguacg gcgccuccuu cgaguucuac aacuacgccu     1740

gcauguucau ggacuacaug uacaacaagg acaugggcau ccucaacaag cucaacgacc     1800

ucgccaagaa caacgacguc gacggcuacg acaacuacau ccgcgaccuc uccuccaacu     1860

acgcccucaa cgacaaguac caggaccaca ugcaggagcg caucgacaac uacgagaacc     1920

ucaccguccc cuucgucgcc gacgacuacc ucguccgcca cgccuacaag aaccccaacg     1980

agaucuacuc cgagaucucc gaggucgcca agcucaagga cgccaagucc gaggucaaga     2040

agucccagua cuucuccacc uucacccucc gcggcuccua caccggcggc gccuccaagg     2100

gcaagcucga ggaccagaag gccaugaaca aguucaucga cgacucccuc aagaagcucg     2160

acaccuacuc cugguccggc uacaagaccc ucaccgccua cuucaccaac uacaaggucg     2220

acuccuccaa ccgcgucacc uacgacgucg ucuuccacgg cuaccucccc aacgagggcg     2280

acuccaagaa cucccucccc uacggcaaga ucaacggcac cuacaagggc accgagaagg     2340

agaagaucaa guucuccucc gagggcuccu ucgaccccga cggcaagauc gucuccuacg     2400

agugggacuu cggcgacggc aacaagucca acgaggagaa ccccgagcac uccuacgaca     2460

aggucggcac cuacaccguc aagcucaagg ucaccgacga caagggcgag uccuccgucu     2520

ccaccaccac cgccgagauc aaggaccucu ccgagaacaa gcuccccguc aucuacaugc     2580

acguccccaa guccggcgcc cucaaccaga aggucgucuu cuacggcaag ggcaccuacg     2640

accccgacgg cuccaucgcc ggcuaccagu gggacuucgg cgacggcucc gacuucuccu     2700

ccgagcagaa ccccucccac gucuacacca agaagggcga guacaccguc acccuccgcg     2760

ucauggacuc cuccggccag auguccgaga agaccaugaa gaucaagauc accgaccccg     2820

ucuaccccau cggcaccgag aaggagccca acaacuccaa ggagaccgcc uccggcccca     2880

ucguccccgg cauccccguc uccggcacca ucgagaacac cuccgaccag gacuacuucu     2940

acuucgacgu caucaccccc ggcgagguca agaucgacau caacaagcuc ggcuacggcg     3000

gcgccaccug ggucgucuac gacgagaaca acaacgccgu cuccuacgcc accgacgacg     3060

gccagaaccu cuccggcaag uucaaggccg acaagcccgg ccgcuacuac auccaccucu     3120

acauguucaa cggcuccuac augcccuacc gcaucaacau cgagggcucc gucggccgcu     3180

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  4003
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt2)

<400>  4003
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcgcaagu gccucuccaa gcgccucaug cucgccauca      120

ccauggccac caucuucacc gucaacucca cccuccccau cuacgccgcc gucgacaaga      180

acaacgccac cgccgccguc cagaacgagu ccaagcgcua caccgucucc uaccucaaga      240

cccucaacua cuacgaccuc gucgaccucc ucgucaagac cgagaucgag aaccuccccg      300

accucuucca guacuccucc gacgccaagg aguucuacgg caacaagacc cgcauguccu      360

ucaucaugga cgagaucggc cgccgcgccc cccaguacac cgagaucgac cacaagggca      420

uccccacccu cgucgagguc guccgcgccg gcuucuaccu cggcuuccac aacaaggagc      480

ucaacgagau caacaagcgc uccuucaagg agcgcgucau ccccuccauc cucgccaucc      540

agaagaaccc caacuucaag cucggcaccg agguccagga caagaucguc uccgccaccg      600

gccuccucgc cggcaacgag accgcccccc ccgaggucgu caacaacuuc acccccaucc      660

uccaggacug caucaagaac aucgaccgcu acgcccucga cgaccucaag uccaaggccc      720

ucuucaacgu ccucgccgcc cccaccuacg acaucaccga guaccuccgc gccaccaagg      780

agaagcccga gaacaccccc ugguacggca agaucgacgg cuucaucaac gagcucaaga      840

agcucgcccu cuacggcaag aucaacgaca acaacuccug gaucaucgac aacggcaucu      900

accacaucgc cccccucggc aagcuccacu ccaacaacaa gaucggcauc gagacccuca      960

ccgaggucau gaaggucuac cccuaccucu ccaugcagca ccuccagucc gccgaccaga     1020

ucaagcgcca cuacgacucc aaggacgccg agggcaacaa gaucccccuc gacaaguuca     1080

agaaggaggg caaggagaag uacugcccca agaccuacac cuucgacgac ggcaagguca     1140

ucaucaaggc cggcgcccgc gucgaggagg agaaggucaa gcgccucuac ugggccucca     1200

aggaggucaa cucccaguuc uuccgcgucu acggcaucga caagccccuc gaggagggca     1260

accccgacga cauccucacc auggucaucu acaacucccc cgaggaguac aagcucaacu     1320

ccguccucua cggcuacgac accaacaacg gcggcaugua caucgagccc gagggcaccu     1380

ucuucaccua cgagcgcgag gcccaggagu ccaccuacac ccucgaggag cucuuccgcc     1440

acgaguacac ccacuaccuc cagggccgcu acgccguccc cggccagugg ggccgcacca     1500

agcucuacga caacgaccgc cucaccuggu acgaggaggg cggcgccgag cucuucgccg     1560

gcuccacccg caccuccggc auccuccccc gcaaguccau cgucuccaac auccacaaca     1620

ccacccgcaa caaccgcuac aagcucuccg acaccgucca cuccaaguac ggcgccuccu     1680

ucgaguucua caacuacgcc ugcauguuca uggacuacau guacaacaag gacaugggca     1740

uccucaacaa gcucaacgac cucgccaaga acaacgacgu cgacggcuac gacaacuaca     1800

uccgcgaccu cuccuccaac uacgcccuca acgacaagua ccaggaccac augcaggagc     1860

gcaucgacaa cuacgagaac cucaccgucc ccuucgucgc cgacgacuac cucguccgcc     1920

acgccuacaa gaaccccaac gagaucuacu ccgagaucuc cgaggucgcc aagcucaagg     1980

acgccaaguc cgaggucaag aagucccagu acuucuccac cuucacccuc cgcggcuccu     2040

acaccggcgg cgccuccaag ggcaagcucg aggaccagaa ggccaugaac aaguucaucg     2100

acgacucccu caagaagcuc gacaccuacu ccugguccgg cuacaagacc cucaccgccu     2160

acuucaccaa cuacaagguc gacuccucca accgcgucac cuacgacguc gucuuccacg     2220

gcuaccuccc caacgagggc gacuccaaga acucccuccc cuacggcaag aucaacggca     2280

ccuacaaggg caccgagaag gagaagauca aguucuccuc cgagggcucc uucgaccccg     2340

acggcaagau cgucuccuac gagugggacu ucggcgacgg caacaagucc aacgaggaga     2400

accccgagca cuccuacgac aaggucggca ccuacaccgu caagcucaag gucaccgacg     2460

acaagggcga guccuccguc uccaccacca ccgccgagau caaggaccuc uccgagaaca     2520

agcuccccgu caucuacaug cacgucccca aguccggcgc ccucaaccag aaggucgucu     2580

ucuacggcaa gggcaccuac gaccccgacg gcuccaucgc cggcuaccag ugggacuucg     2640

gcgacggcuc cgacuucucc uccgagcaga accccuccca cgucuacacc aagaagggcg     2700

aguacaccgu cacccuccgc gucauggacu ccuccggcca gauguccgag aagaccauga     2760

agaucaagau caccgacccc gucuacccca ucggcaccga gaaggagccc aacaacucca     2820

aggagaccgc cuccggcccc aucguccccg gcauccccgu cuccggcacc aucgagaaca     2880

ccuccgacca ggacuacuuc uacuucgacg ucaucacccc cggcgagguc aagaucgaca     2940

ucaacaagcu cggcuacggc ggcgccaccu gggucgucua cgacgagaac aacaacgccg     3000

ucuccuacgc caccgacgac ggccagaacc ucuccggcaa guucaaggcc gacaagcccg     3060

gccgcuacua cauccaccuc uacauguuca acggcuccua caugcccuac cgcaucaaca     3120

ucgagggcuc cgucggccgc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  4004
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt2)

<400>  4004
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguca ccuucaucuc ccuccucuuc cucuucuccu      120

ccgccuacuc cguccagaac gaguccaagc gcuacaccgu cuccuaccuc aagacccuca      180

acuacuacga ccucgucgac cuccucguca agaccgagau cgagaaccuc cccgaccucu      240

uccaguacuc cuccgacgcc aaggaguucu acggcaacaa gacccgcaug uccuucauca      300

uggacgagau cggccgccgc gccccccagu acaccgagau cgaccacaag ggcaucccca      360

cccucgucga ggucguccgc gccggcuucu accucggcuu ccacaacaag gagcucaacg      420

agaucaacaa gcgcuccuuc aaggagcgcg ucauccccuc cauccucgcc auccagaaga      480

accccaacuu caagcucggc accgaggucc aggacaagau cgucuccgcc accggccucc      540

ucgccggcaa cgagaccgcc ccccccgagg ucgucaacaa cuucaccccc auccuccagg      600

acugcaucaa gaacaucgac cgcuacgccc ucgacgaccu caaguccaag gcccucuuca      660

acguccucgc cgcccccacc uacgacauca ccgaguaccu ccgcgccacc aaggagaagc      720

ccgagaacac ccccugguac ggcaagaucg acggcuucau caacgagcuc aagaagcucg      780

cccucuacgg caagaucaac gacaacaacu ccuggaucau cgacaacggc aucuaccaca      840

ucgccccccu cggcaagcuc cacuccaaca acaagaucgg caucgagacc cucaccgagg      900

ucaugaaggu cuaccccuac cucuccaugc agcaccucca guccgccgac cagaucaagc      960

gccacuacga cuccaaggac gccgagggca acaagauccc ccucgacaag uucaagaagg     1020

agggcaagga gaaguacugc cccaagaccu acaccuucga cgacggcaag gucaucauca     1080

aggccggcgc ccgcgucgag gaggagaagg ucaagcgccu cuacugggcc uccaaggagg     1140

ucaacuccca guucuuccgc gucuacggca ucgacaagcc ccucgaggag ggcaaccccg     1200

acgacauccu caccaugguc aucuacaacu cccccgagga guacaagcuc aacuccgucc     1260

ucuacggcua cgacaccaac aacggcggca uguacaucga gcccgagggc accuucuuca     1320

ccuacgagcg cgaggcccag gaguccaccu acacccucga ggagcucuuc cgccacgagu     1380

acacccacua ccuccagggc cgcuacgccg uccccggcca guggggccgc accaagcucu     1440

acgacaacga ccgccucacc ugguacgagg agggcggcgc cgagcucuuc gccggcucca     1500

cccgcaccuc cggcauccuc ccccgcaagu ccaucgucuc caacauccac aacaccaccc     1560

gcaacaaccg cuacaagcuc uccgacaccg uccacuccaa guacggcgcc uccuucgagu     1620

ucuacaacua cgccugcaug uucauggacu acauguacaa caaggacaug ggcauccuca     1680

acaagcucaa cgaccucgcc aagaacaacg acgucgacgg cuacgacaac uacauccgcg     1740

accucuccuc caacuacgcc cucaacgaca aguaccagga ccacaugcag gagcgcaucg     1800

acaacuacga gaaccucacc guccccuucg ucgccgacga cuaccucguc cgccacgccu     1860

acaagaaccc caacgagauc uacuccgaga ucuccgaggu cgccaagcuc aaggacgcca     1920

aguccgaggu caagaagucc caguacuucu ccaccuucac ccuccgcggc uccuacaccg     1980

gcggcgccuc caagggcaag cucgaggacc agaaggccau gaacaaguuc aucgacgacu     2040

cccucaagaa gcucgacacc uacuccuggu ccggcuacaa gacccucacc gccuacuuca     2100

ccaacuacaa ggucgacucc uccaaccgcg ucaccuacga cgucgucuuc cacggcuacc     2160

uccccaacga gggcgacucc aagaacuccc uccccuacgg caagaucaac ggcaccuaca     2220

agggcaccga gaaggagaag aucaaguucu ccuccgaggg cuccuucgac cccgacggca     2280

agaucgucuc cuacgagugg gacuucggcg acggcaacaa guccaacgag gagaaccccg     2340

agcacuccua cgacaagguc ggcaccuaca ccgucaagcu caaggucacc gacgacaagg     2400

gcgaguccuc cgucuccacc accaccgccg agaucaagga ccucuccgag aacaagcucc     2460

ccgucaucua caugcacguc cccaaguccg gcgcccucaa ccagaagguc gucuucuacg     2520

gcaagggcac cuacgacccc gacggcucca ucgccggcua ccagugggac uucggcgacg     2580

gcuccgacuu cuccuccgag cagaaccccu cccacgucua caccaagaag ggcgaguaca     2640

ccgucacccu ccgcgucaug gacuccuccg gccagauguc cgagaagacc augaagauca     2700

agaucaccga ccccgucuac cccaucggca ccgagaagga gcccaacaac uccaaggaga     2760

ccgccuccgg ccccaucguc cccggcaucc ccgucuccgg caccaucgag aacaccuccg     2820

accaggacua cuucuacuuc gacgucauca cccccggcga ggucaagauc gacaucaaca     2880

agcucggcua cggcggcgcc accugggucg ucuacgacga gaacaacaac gccgucuccu     2940

acgccaccga cgacggccag aaccucuccg gcaaguucaa ggccgacaag cccggccgcu     3000

acuacaucca ccucuacaug uucaacggcu ccuacaugcc cuaccgcauc aacaucgagg     3060

gcuccgucgg ccgcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4005
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt2)

<400>  4005
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguca ccuucaucuc ccuccucuuc cucuucuccu      120

ccgccuacuc caugaagcgc aagugccucu ccaagcgccu caugcucgcc aucaccaugg      180

ccaccaucuu caccgucaac uccacccucc ccaucuacgc cgccgucgac aagaacaacg      240

ccaccgccgc ccgccgccgc cgcaagcgcg uccagaacga guccaagcgc uacaccgucu      300

ccuaccucaa gacccucaac uacuacgacc ucgucgaccu ccucgucaag accgagaucg      360

agaaccuccc cgaccucuuc caguacuccu ccgacgccaa ggaguucuac ggcaacaaga      420

cccgcauguc cuucaucaug gacgagaucg gccgccgcgc cccccaguac accgagaucg      480

accacaaggg cauccccacc cucgucgagg ucguccgcgc cggcuucuac cucggcuucc      540

acaacaagga gcucaacgag aucaacaagc gcuccuucaa ggagcgcguc auccccucca      600

uccucgccau ccagaagaac cccaacuuca agcucggcac cgagguccag gacaagaucg      660

ucuccgccac cggccuccuc gccggcaacg agaccgcccc ccccgagguc gucaacaacu      720

ucacccccau ccuccaggac ugcaucaaga acaucgaccg cuacgcccuc gacgaccuca      780

aguccaaggc ccucuucaac guccucgccg cccccaccua cgacaucacc gaguaccucc      840

gcgccaccaa ggagaagccc gagaacaccc ccugguacgg caagaucgac ggcuucauca      900

acgagcucaa gaagcucgcc cucuacggca agaucaacga caacaacucc uggaucaucg      960

acaacggcau cuaccacauc gccccccucg gcaagcucca cuccaacaac aagaucggca     1020

ucgagacccu caccgagguc augaaggucu accccuaccu cuccaugcag caccuccagu     1080

ccgccgacca gaucaagcgc cacuacgacu ccaaggacgc cgagggcaac aagauccccc     1140

ucgacaaguu caagaaggag ggcaaggaga aguacugccc caagaccuac accuucgacg     1200

acggcaaggu caucaucaag gccggcgccc gcgucgagga ggagaagguc aagcgccucu     1260

acugggccuc caaggagguc aacucccagu ucuuccgcgu cuacggcauc gacaagcccc     1320

ucgaggaggg caaccccgac gacauccuca ccauggucau cuacaacucc cccgaggagu     1380

acaagcucaa cuccguccuc uacggcuacg acaccaacaa cggcggcaug uacaucgagc     1440

ccgagggcac cuucuucacc uacgagcgcg aggcccagga guccaccuac acccucgagg     1500

agcucuuccg ccacgaguac acccacuacc uccagggccg cuacgccguc cccggccagu     1560

ggggccgcac caagcucuac gacaacgacc gccucaccug guacgaggag ggcggcgccg     1620

agcucuucgc cggcuccacc cgcaccuccg gcauccuccc ccgcaagucc aucgucucca     1680

acauccacaa caccacccgc aacaaccgcu acaagcucuc cgacaccguc cacuccaagu     1740

acggcgccuc cuucgaguuc uacaacuacg ccugcauguu cauggacuac auguacaaca     1800

aggacauggg cauccucaac aagcucaacg accucgccaa gaacaacgac gucgacggcu     1860

acgacaacua cauccgcgac cucuccucca acuacgcccu caacgacaag uaccaggacc     1920

acaugcagga gcgcaucgac aacuacgaga accucaccgu ccccuucguc gccgacgacu     1980

accucguccg ccacgccuac aagaacccca acgagaucua cuccgagauc uccgaggucg     2040

ccaagcucaa ggacgccaag uccgagguca agaaguccca guacuucucc accuucaccc     2100

uccgcggcuc cuacaccggc ggcgccucca agggcaagcu cgaggaccag aaggccauga     2160

acaaguucau cgacgacucc cucaagaagc ucgacaccua cuccuggucc ggcuacaaga     2220

cccucaccgc cuacuucacc aacuacaagg ucgacuccuc caaccgcguc accuacgacg     2280

ucgucuucca cggcuaccuc cccaacgagg gcgacuccaa gaacucccuc cccuacggca     2340

agaucaacgg caccuacaag ggcaccgaga aggagaagau caaguucucc uccgagggcu     2400

ccuucgaccc cgacggcaag aucgucuccu acgaguggga cuucggcgac ggcaacaagu     2460

ccaacgagga gaaccccgag cacuccuacg acaaggucgg caccuacacc gucaagcuca     2520

aggucaccga cgacaagggc gaguccuccg ucuccaccac caccgccgag aucaaggacc     2580

ucuccgagaa caagcucccc gucaucuaca ugcacguccc caaguccggc gcccucaacc     2640

agaaggucgu cuucuacggc aagggcaccu acgaccccga cggcuccauc gccggcuacc     2700

agugggacuu cggcgacggc uccgacuucu ccuccgagca gaaccccucc cacgucuaca     2760

ccaagaaggg cgaguacacc gucacccucc gcgucaugga cuccuccggc cagauguccg     2820

agaagaccau gaagaucaag aucaccgacc ccgucuaccc caucggcacc gagaaggagc     2880

ccaacaacuc caaggagacc gccuccggcc ccaucguccc cggcaucccc gucuccggca     2940

ccaucgagaa caccuccgac caggacuacu ucuacuucga cgucaucacc cccggcgagg     3000

ucaagaucga caucaacaag cucggcuacg gcggcgccac cugggucguc uacgacgaga     3060

acaacaacgc cgucuccuac gccaccgacg acggccagaa ccucuccggc aaguucaagg     3120

ccgacaagcc cggccgcuac uacauccacc ucuacauguu caacggcucc uacaugcccu     3180

accgcaucaa caucgagggc uccgucggcc gcugaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  4006
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt2)

<400>  4006
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucgccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagucca uccgcccccc cuaccccucc uacggcuacg      240

agcccauggg cggcuggcuc caccaccaga ucauccccgu ccucucccag cagcaccccc      300

ccacccacac ccuccagccc caccaccaca uccccgucgu ccccgcccag cagcccguca      360

ucccccagca gcccaugaug cccguccccg gccagcacuc caugaccccc auccagcacc      420

accagcccaa ccuccccccc cccgcccagc agcccuacca gccccagccc guccagcccc      480

agccccacca gcccaugcag ccccagcccc ccguccaccc caugcagccc cucccccccc      540

agcccccccu cccccccaug uuccccaugc agccccuccc ccccaugcuc cccgaccuca      600

cccucgaggc cuggcccucc accgacaaga ccaagcgcga ggaggucgac ugaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  4007
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt2)

<400>  4007
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccaguc cauccgcccc cccuaccccu      180

ccuacggcua cgagcccaug ggcggcuggu gaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  4008
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt2)

<400>  4008
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccaguc cauccgcccc ccccccaugc      180

uccccgaccu cacccucgag gccuggcccu ccaccgacaa gaccaagcgc gaggaggucg      240

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  4009
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt2)

<400>  4009
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccag accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gagguccuca ccccccucaa gugguaccag uccauccgcc      240

cccccuaccc cuccuacggc uacgagccca ugggcggcug gugaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  4010
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt2)

<400>  4010
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccag accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gagguccuca ccccccucaa gugguaccag uccauccgcc      240

ccccccccau gcuccccgac cucacccucg aggccuggcc cuccaccgac aagaccaagc      300

gcgaggaggu cgacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  4011
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt2)

<400>  4011
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccucguc ggcgccgccu      120

ucgccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagucca ugauccgccc ccccuacucc uccuacggcu      240

acgagcccau gggcggcugg cuccaccacc agaucauccc cgucgucucc cagcagcacc      300

cccucaccca cacccuccag ucccaccacc acauccccgu cguccccgcc cagcagcccc      360

gcguccgcca gcaggcccuc augcccgucc ccggccagca guccaugacc cccacccagc      420

accaccagcc caaccucccc cuccccgccc agcagcccuu ccagccccag cccguccagc      480

cccagcccca ccagcccaug cagccccagc cccccgucca gcccaugcag ccccuccucc      540

cccagccccc ccuccccccc auguuccccc uccgcccccu cccccccauc cuccccgacc      600

uccaccucga ggccuggccc gccaccgaca agaccaagca ggaggagguc gacugaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  4012
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt2)

<400>  4012
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccaguc caugauccgc ccccccuacu      180

ccuccuacgg cuacgagccc augggcggcu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4013
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt2)

<400>  4013
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccaguc caugauccgc ccccccccca      180

uccuccccga ccuccaccuc gaggccuggc ccgccaccga caagaccaag caggaggagg      240

ucgacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4014
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt2)

<400>  4014
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccag accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gagguccuca ccccccucaa gugguaccag uccaugaucc      240

gcccccccua cuccuccuac ggcuacgagc ccaugggcgg cuggugagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4015
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt2)

<400>  4015
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccag accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gagguccuca ccccccucaa gugguaccag uccaugaucc      240

gccccccccc cauccucccc gaccuccacc ucgaggccug gcccgccacc gacaagacca      300

agcaggagga ggucgacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4016
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt2)

<400>  4016
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccuacacc uccuacggcu      240

acgagcccau gggcggcugg cuccaccacc agaucauccc cgucgucucc cagcagaccc      300

cccaguccca cgcccuccag ccccaccacc acauccccau gguccccgcc cagcagcccg      360

gcauccccca gcagcccaug augccccucc ccggccagca cuccaugacc cccacccagc      420

accaccagcc caaccucccc cuccccgccc agcagcccuu ccagccccag cccguccagc      480

cccagcccca ccagccccuc cagccccagu cccccaugca ccccauccag ccccuccucc      540

cccagccccc ccuccccccc auguucucca ugcagucccu ccuccccgac cucccccucg      600

aggccuggcc cgccaccgac aagaccaagc gcgaggaggu cgacugagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4017
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt2)

<400>  4017
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccagaa caugauccgc caccccuaca      180

ccuccuacgg cuacgagccc augggcggcu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4018
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt2)

<400>  4018
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccagaa caugauccgc caccccuccc      180

uccuccccga ccucccccuc gaggccuggc ccgccaccga caagaccaag cgcgaggagg      240

ucgacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4019
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt2)

<400>  4019
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccag accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gagguccuca ccccccucaa gugguaccag aacaugaucc      240

gccaccccua caccuccuac ggcuacgagc ccaugggcgg cuggugagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4020
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt2)

<400>  4020
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccag accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gagguccuca ccccccucaa gugguaccag aacaugaucc      240

gccaccccuc ccuccucccc gaccuccccc ucgaggccug gcccgccacc gacaagacca      300

agcgcgagga ggucgacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4021
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt2)

<400>  4021
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacaucc      180

gccaccccua caccuccuac ggcuacgagc ccaugggcgg cuggcuccac caccagauca      240

uccccgucgu cucccagcag accccccagu cccacgcccu ccagccccac caccacaucc      300

ccaugguccc cgcccagcag cccggcaucc cccagcagcc caugaugccc cuccccggcc      360

agcacuccau gacccccacc cagcaccacc agcccaaccu cccccucccc gcccagcagc      420

ccuuccagcc ccagcccguc cagccccagc cccaccagcc ccuccagccc caguccccca      480

ugcaccccau ccagccccuc cucccccagc ccccccuccc ccccauguuc uccaugcagu      540

cccuccuccc cgaccucccc cucgaggccu ggcccgccac cgacaagacc aagcgcgagg      600

aggucgacug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  4022
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt2)

<400>  4022
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuucgc cugccuccuc ggcgccuccc      120

ucgccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccuacacc uccuacggcu      240

acgagcccau gggcggcugg cuccaccacc agaucauccc cgucgucucc cagcagaccc      300

cccaguccca cgcccuccag ccccaccacc acauccccau gguccccgcc cagcagcccg      360

gcauccccca gcagcccaug augccccucc ccggccagca cuccaugacc cccacccagc      420

accaccagcc caaccucccc cuccccgccc agcagcccuu ccagccccag cccguccagc      480

cccagcccca ccagccccuc cagccccagu cccccaugca ccccauccag ccccuccucc      540

cccagccccc ccuccccccc auguucucca ugcagucccu ccuccccgac cucccccucg      600

aggccuggcc cgccaccgac aagaccaagc gcgaggaggu cgacugagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4023
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt2)

<400>  4023
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccucccuc cuccccgacc      240

ucccccucga ggccuggccc gccaccgaca agaccaagcg cgaggagguc gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  4024
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt2)

<400>  4024
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

accucuaccu cgaggccauc cgcaucgacc gcaccgccuu cguccucacc ccccucaagu      240

gguaccagaa caugauccgc caccccuaca ccuccuacgg cuacgagccc augggcggcu      300

ggcuccacca ccagaucauc cccgucgucu cccagcagac cccccagucc cacgcccucc      360

agccccacca ccacaucccc augguccccg cccagcagcc cggcaucccc cagcagccca      420

ugaugccccu ccccggccag cacuccauga cccccaccca gcaccaccag cccaaccucc      480

cccuccccgc ccagcagccc uuccagcccc agcccgucca gccccagccc caccagcccc      540

uccagcccca gucccccaug caccccaucc agccccuccu cccccagccc ccccuccccc      600

ccauguucuc caugcagucc cuccuccccg accucccccu cgaggccugg cccgccaccg      660

acaagaccaa gcgcgaggag gucgacugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  4025
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt2)

<400>  4025
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccaccccc cagucccacg      240

cccuccagcc ccaccaccac auccccaugg uccccgccca gcagcccggc aucccccagc      300

agcccaugau gccccucccc ggccagcacu ccaugacccc cacccagcac caccagccca      360

accucccccu ccccgcccag cagcccuucc agccccagcc cguccagccc cagccccacc      420

agccccucca gccccagucc cccaugcacc ccauccagcc ccuccucccc cagccccccc      480

ucccccccau guucuccaug cagucccucc uccccgaccu cccccucgag gccuggcccg      540

ccaccgacaa gaccaagcgc gaggaggucg acugaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  4026
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt2)

<400>  4026
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccagaa caugauccgc caccccuaca      180

ccuccuacgg cuacgagccc augggcggcu ggcuccacca ccagaucauc cccgucgucu      240

cccagcagac cccccagucc cacgcccucc agccccacca ccacaucccc augguccccg      300

cccagcagcc cggcaucccc cagcagccca ugaugccccu ccccggccag cacuccauga      360

cccccaccca gcaccaccag cccaaccucc cccuccccgc ccagcagccc uuccagcccc      420

agcccgucca gccccagccc caccagcccc uccagcccca gucccccaug caccccaucc      480

agccccuccu cccccagccc ccccuccccc ccauguucuc caugcagucc cuccuccccg      540

accucccccu cgaggccugg cccgccaccg acaagaccaa gcgcgaggag gucgacugag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  4027
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt2)

<400>  4027
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgucg cccgccuccc ccuccuccuc ggccuccucc      120

uccucccccg ccccggccgc ccccucgacc ucgccgacua caccuacgac cucgccgagg      180

aggacgacuc cgagccccuc aacuacaagg accccugcaa ggccgccgcc uuccucggcg      240

acaucgcccu cgacgaggag gaccuccgcg ccuuccaggu ccagcaggcc gucgaccucc      300

gccgccacac cgcccgcaag uccuccauca aggccgccgu ccccggcaac accuccaccc      360

ccuccugcca guccaccaac ggccagcccc agcgcggcgc cugcggccgc uggcgcggcc      420

gcucccgcuc ccgccgcgcc gccaccuccc gccccgagcg cgucuggccc gacggcguca      480

uccccuucgu caucggcggc aacuucaccg gcucccagcg cgccgucuuc cgccaggcca      540

ugcgccacug ggagaagcac accugcguca ccuuccucga gcgcaccgac gaggacuccu      600

acaucgucuu caccuaccgc cccugcggcu gcugcuccua cgucggccgc cgcggcggcg      660

gcccccaggc caucuccauc ggcaagaacu gcgacaaguu cggcaucguc guccacgagc      720

ucggccacgu cgucggcuuc uggcacgagc acacccgccc cgaccgcgac cgccacgucu      780

ccaucguccg cgagaacauc cagcccggcc aggaguacaa cuuccucaag auggagcccc      840

aggaggucga gucccucggc gagaccuacg acuucgacuc caucaugcac uacgcccgca      900

acaccuucuc ccgcggcauc uuccucgaca ccaucguccc caaguacgag gucaacggcg      960

ucaagccccc caucggccag cgcacccgcc ucuccaaggg cgacaucgcc caggcccgca     1020

agcucuacaa gugccccgcc ugcggcgaga cccuccagga cuccaccggc aacuucuccu     1080

cccccgagua ccccaacggc uacuccgccc acaugcacug cgucuggcgc aucuccguca     1140

cccccggcga gaagaucauc cucaacuuca ccucccucga ccucuaccgc ucccgccucu     1200

gcugguacga cuacgucgag guccgcgacg gcuucuggcg caaggccccc cuccgcggcc     1260

gcuucugcgg cuccaagcuc cccgagccca ucgucuccac cgacucccgc cucugggucg     1320

aguuccgcuc cuccuccaac ugggucggca agggcuucuu cgccgucuac gaggccaucu     1380

gcggcggcga cgucaagaag gacuacggcc acauccaguc ccccaacuac cccgacgacu     1440

accgccccuc caaggucugc aucuggcgca uccaggucuc cgagggcuuc cacgucggcc     1500

ucaccuucca guccuucgag aucgagcgcc acgacuccug cgccuacgac uaccucgagg     1560

uccgcgacgg ccacuccgag uccuccaccc ucaucggccg cuacugcggc uacgagaagc     1620

ccgacgacau caaguccacc uccucccgcc ucuggcucaa guucgucucc gacggcucca     1680

ucaacaaggc cggcuucgcc gucaacuucu ucaaggaggu cgacgagugc ucccgcccca     1740

accgcggcgg cugcgagcag cgcugccuca acacccucgg cuccuacaag ugcuccugcg     1800

accccggcua cgagcucgcc cccgacaagc gccgcugcga ggccgccugc ggcggcuucc     1860

ucaccaagcu caacggcucc aucaccuccc ccggcuggcc caaggaguac ccccccaaca     1920

agaacugcau cuggcagcuc gucgccccca cccaguaccg caucucccuc caguucgacu     1980

ucuucgagac cgagggcaac gacgucugca aguacgacuu cgucgagguc cgcuccggcc     2040

ucaccgccga cuccaagcuc cacggcaagu ucugcggcuc cgagaagccc gaggucauca     2100

ccucccagua caacaacaug cgcgucgagu ucaaguccga caacaccguc uccaagaagg     2160

gcuucaaggc ccacuucuuc uccgacaagg acgagugcuc caaggacaac ggcggcugcc     2220

agcaggacug cgucaacacc uucggcuccu acgagugcca gugccgcucc ggcuucgucc     2280

uccacgacaa caagcacgac ugcaaggagg ccggcugcga ccacaagguc accuccaccu     2340

ccggcaccau caccuccccc aacuggcccg acaaguaccc cuccaagaag gagugcaccu     2400

gggccaucuc cuccaccccc ggccaccgcg ucaagcucac cuucauggag auggacaucg     2460

agucccagcc cgagugcgcc uacgaccacc ucgaggucuu cgacggccgc gacgccaagg     2520

cccccguccu cggccgcuuc ugcggcucca agaagcccga gcccguccuc gccaccggcu     2580

cccgcauguu ccuccgcuuc uacuccgaca acuccgucca gcgcaagggc uuccaggccu     2640

cccacgccac cgagugcggc ggccaggucc gcgccgacgu caagaccaag gaccucuacu     2700

cccacgccca guucggcgac aacaacuacc ccggcggcgu cgacugcgag ugggucaucg     2760

ucgccgagga gggcuacggc gucgagcucg ucuuccagac cuucgagguc gaggaggaga     2820

ccgacugcgg cuacgacuac auggagcucu ucgacggcua cgacuccacc gccccccgcc     2880

ucggccgcua cugcggcucc ggcccccccg aggaggucua cuccgccggc gacuccgucc     2940

ucgucaaguu ccacuccgac gacaccauca ccaagaaggg cuuccaccuc cgcuacaccu     3000

ccaccaaguu ccaggacacc cuccacuccc gcaagugagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  4028
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt2)

<400>  4028
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgccggca cccgcugccu ccucgcccuc cuccuccccc      120

agguccuccu cggcggcgcc gccggccucg uccccgagcu cggccgccgc aaguucgccg      180

ccgccuccuc cggccgcccc uccucccagc ccuccgacga gguccucucc gaguucgagc      240

uccgccuccu cuccauguuc ggccucaagc agcgccccac ccccucccgc gacgccgucg      300

ucccccccua caugcucgac cucuaccgcc gccacuccgg ccagcccggc ucccccgccc      360

ccgaccaccg ccucgagcgc gccgccuccc gcgccaacac cguccgcucc uuccaccacg      420

aggagucccu cgaggagcuc cccgagaccu ccggcaagac cacccgccgc uucuucuuca      480

accucuccuc cauccccacc gaggaguuca ucaccuccgc cgagcuccag gucuuccgcg      540

agcagaugca ggacgcccuc ggcaacaacu ccuccuucca ccaccgcauc aacaucuacg      600

agaucaucaa gcccgccacc gccaacucca aguuccccgu cacccgccuc cucgacaccc      660

gccucgucaa ccagaacgcc ucccgcuggg aguccuucga cgucaccccc gccgucaugc      720

gcuggaccgc ccagggccac gccaaccacg gcuucgucgu cgaggucgcc caccucgagg      780

agaagcaggg cgucuccaag cgccacgucc gcaucucccg cucccuccac caggacgagc      840

acuccugguc ccagauccgc ccccuccucg ucaccuucgg ccacgacggc aagggccacc      900

cccuccacaa gcgcgagaag cgccaggcca agcacaagca gcgcaagcgc cucaaguccu      960

ccugcaagcg ccacccccuc uacgucgacu ucuccgacgu cggcuggaac gacuggaucg     1020

ucgccccccc cggcuaccac gccuucuacu gccacggcga gugccccuuc ccccucgccg     1080

accaccucaa cuccaccaac cacgccaucg uccagacccu cgucaacucc gucaacucca     1140

agauccccaa ggccugcugc guccccaccg agcucuccgc caucuccaug cucuaccucg     1200

acgagaacga gaaggucguc cucaagaacu accaggacau ggucgucgag ggcugcggcu     1260

gccgcugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  4029
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt2)

<400>  4029
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auccccggca accgcaugcu cauggucguc cuccucugcc      120

agguccuccu cggcggcgcc ucccacgccu cccucauccc cgagaccggc aagaagaagg      180

ucgccgagau ccagggccac gccggcggcc gccgcuccgg ccagucccac gagcuccucc      240

gcgacuucga ggccacccuc cuccagaugu ucggccuccg ccgccgcccc cagcccucca      300

aguccgccgu cauccccgac uacaugcgcg accucuaccg ccuccagucc ggcgaggagg      360

aggaggagca gauccacucc accggccucg aguaccccga gcgccccgcc ucccgcgcca      420

acaccguccg cuccuuccac cacgaggagc accucgagaa cauccccggc accuccgaga      480

acuccgccuu ccgcuuccuc uucaaccucu ccuccauccc cgagaacgag gucaucuccu      540

ccgccgagcu ccgccucuuc cgcgagcagg ucgaccaggg ccccgacugg gagcgcggcu      600

uccaccgcau caacaucuac gaggucauga agccccccgc cgaggucguc cccggccacc      660

ucaucacccg ccuccucgac acccgccucg uccaccacaa cgucacccgc ugggagaccu      720

ucgacgucuc ccccgccguc cuccgcugga cccgcgagaa gcagcccaac uacggccucg      780

ccaucgaggu cacccaccuc caccagaccc gcacccacca gggccagcac guccgcaucu      840

cccgcucccu cccccagggc uccggcaacu gggcccagcu ccgcccccuc cucgucaccu      900

ucggccacga cggccgcggc cacgcccuca cccgccgccg ccgcgccaag cgcuccccca      960

agcaccacuc ccagcgcgcc cgcaagaaga acaagaacug ccgccgccac ucccucuacg     1020

ucgacuucuc cgacgucggc uggaacgacu ggaucgucgc cccccccggc uaccaggccu     1080

ucuacugcca cggcgacugc cccuuccccc ucgccgacca ccucaacucc accaaccacg     1140

ccaucgucca gacccucguc aacuccguca acuccuccau ccccaaggcc ugcugcgucc     1200

ccaccgagcu cuccgccauc uccaugcucu accucgacga guacgacaag gucguccuca     1260

agaacuacca ggagaugguc gucgagggcu gcggcugccg cugaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  4030
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt2)

<400>  4030
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggccucg gccgccgcgc ccaguggcuc ugcugguggu      120

ggggccuccu cugcuccugc ugcggccccc ccccccuccg ccccccccuc cccgccgccg      180

ccgccgccgc cgccggcggc cagcuccucg gcgacggcgg cucccccggc cgcaccgagc      240

agcccccccc cuccccccag uccuccuccg gcuuccucua ccgccgccuc aagacccagg      300

agaagcgcga gaugcagaag gagauccucu ccguccucgg ccucccccac cgcccccgcc      360

cccuccacgg ccuccagcag ccccagcccc ccgcccuccg ccagcaggag gagcagcagc      420

agcagcagca gcucccccgc ggcgagcccc cccccggccg ccucaagucc gccccccucu      480

ucaugcucga ccucuacaac gcccucuccg ccgacaacga cgaggacggc gccuccgagg      540

gcgagcgcca gcaguccugg ccccacgagg ccgccuccuc cucccagcgc cgccagcccc      600

cccccggcgc cgcccacccc cucaaccgca agucccuccu cgcccccggc uccggcuccg      660

gcggcgccuc cccccucacc uccgcccagg acuccgccuu ccucaacgac gccgacaugg      720

ucauguccuu cgucaaccuc gucgaguacg acaaggaguu cuccccccgc cagcgccacc      780

acaaggaguu caaguucaac cucucccaga uccccgaggg cgaggucguc accgccgccg      840

aguuccgcau cuacaaggac ugcgucaugg gcuccuucaa gaaccagacc uuccucaucu      900

ccaucuacca gguccuccag gagcaccagc accgcgacuc cgaccucuuc cuccucgaca      960

cccgcgucgu cugggccucc gaggagggcu ggcucgaguu cgacaucacc gccaccucca     1020

accucugggu cgucaccccc cagcacaaca ugggccucca gcucuccguc gucacccgcg     1080

acggcgucca cguccacccc cgcgccgccg gccucgucgg ccgcgacggc cccuacgaca     1140

agcagcccuu cauggucgcc uucuucaagg ucuccgaggu ccacguccgc accacccgcu     1200

ccgccuccuc ccgccgccgc cagcaguccc gcaaccgcuc cacccagucc caggacgucg     1260

cccgcgucuc cuccgccucc gacuacaacu ccuccgagcu caagaccgcc ugccgcaagc     1320

acgagcucua cgucuccuuc caggaccucg gcuggcagga cuggaucauc gcccccaagg     1380

gcuacgccgc caacuacugc gacggcgagu gcuccuuccc ccucaacgcc cacaugaacg     1440

ccaccaacca cgccaucguc cagacccucg uccaccucau gaaccccgag uacgucccca     1500

agcccugcug cgcccccacc aagcucaacg ccaucuccgu ccucuacuuc gacgacaacu     1560

ccaacgucau ccucaagaag uaccgcaaca uggucguccg cgccugcggc ugccacugag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  4031
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt2)

<400>  4031
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacguccgcu cccuccgcgc cgccgccccc cacuccuucg      120

ucgcccucug ggccccccuc uuccuccucc gcuccgcccu cgccgacuuc ucccucgaca      180

acgaggucca cuccuccuuc auccaccgcc gccuccgcuc ccaggagcgc cgcgagaugc      240

agcgcgagau ccucuccauc cucggccucc cccaccgccc ccgcccccac cuccagggca      300

agcacaacuc cgcccccaug uucaugcucg accucuacaa cgccauggcc gucgaggagg      360

gcggcggccc cggcggccag ggcuucuccu accccuacaa ggccgucuuc uccacccagg      420

gccccccccu cgccucccuc caggacuccc acuuccucac cgacgccgac auggucaugu      480

ccuucgucaa ccucgucgag cacgacaagg aguucuucca cccccgcuac caccaccgcg      540

aguuccgcuu cgaccucucc aagauccccg agggcgaggc cgucaccgcc gccgaguucc      600

gcaucuacaa ggacuacauc cgcgagcgcu ucgacaacga gaccuuccgc aucuccgucu      660

accagguccu ccaggagcac cucggccgcg aguccgaccu cuuccuccuc gacucccgca      720

cccucugggc cuccgaggag ggcuggcucg ucuucgacau caccgccacc uccaaccacu      780

gggucgucaa cccccgccac aaccucggcc uccagcucuc cgucgagacc cucgacggcc      840

aguccaucaa ccccaagcuc gccggccuca ucggccgcca cggcccccag aacaagcagc      900

ccuucauggu cgccuucuuc aaggccaccg agguccacuu ccgcuccauc cgcuccaccg      960

gcuccaagca gcgcucccag aaccgcucca agacccccaa gaaccaggag gcccuccgca     1020

uggccaacgu cgccgagaac uccuccuccg accagcgcca ggccugcaag aagcacgagc     1080

ucuacgucuc cuuccgcgac cucggcuggc aggacuggau caucgccccc gagggcuacg     1140

ccgccuacua cugcgagggc gagugcgccu ucccccucaa cuccuacaug aacgccacca     1200

accacgccau cguccagacc cucguccacu ucaucaaccc cgagaccguc cccaagcccu     1260

gcugcgcccc cacccagcuc aacgccaucu ccguccucua cuucgacgac uccuccaacg     1320

ucauccucaa gaaguaccgc aacauggucg uccgcgccug cggcugccac ugaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  4032
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt2)

<400>  4032
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggccuccg ccgcccuccu cugccuccuc cucaccgccg      120

ccgccuucuc cccccagggc cucgcccagc ccgucggcau caacaccucc accaccugcu      180

gcuaccgcuu caucaacaag aagaucccca agcagcgccu cgaguccuac cgccgcacca      240

ccuccuccca cugcccccgc gaggccguca ucuucaagac caagcucgac aaggagaucu      300

gcgccgaccc cacccagaag uggguccagg acuucaugaa gcaccucgac aagaagaccc      360

agacccccaa gcucugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  4033
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt2)

<400>  4033
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuccucaccc ucaucauccu ccuccccguc gucuccaagu      120

ucuccuucgu cucccucucc gccccccagc acugguccug ccccgagggc acccucgccg      180

gcaacggcaa cuccaccugc gucggccccg cccccuuccu caucuucucc cacggcaacu      240

ccaucuuccg caucgacacc gagggcacca acuacgagca gcucgucguc gacgccggcg      300

ucuccgucau cauggacuuc cacuacaacg agaagcgcau cuacuggguc gaccucgagc      360

gccagcuccu ccagcgcguc uuccucaacg gcucccgcca ggagcgcguc ugcaacaucg      420

agaagaacgu cuccggcaug gccaucaacu ggaucaacga ggaggucauc ugguccaacc      480

agcaggaggg caucaucacc gucaccgaca ugaagggcaa caacucccac auccuccucu      540

ccgcccucaa guaccccgcc aacgucgccg ucgaccccgu cgagcgcuuc aucuucuggu      600

ccuccgaggu cgccggcucc cucuaccgcg ccgaccucga cggcgucggc gucaaggccc      660

uccucgagac cuccgagaag aucaccgccg ucucccucga cguccucgac aagcgccucu      720

ucuggaucca guacaaccgc gagggcucca acucccucau cugcuccugc gacuacgacg      780

gcggcuccgu ccacaucucc aagcacccca cccagcacaa ccucuucgcc augucccucu      840

ucggcgaccg caucuucuac uccaccugga agaugaagac caucuggauc gccaacaagc      900

acaccggcaa ggacaugguc cgcaucaacc uccacuccuc cuucgucccc cucggcgagc      960

ucaaggucgu ccacccccuc gcccagccca aggccgagga cgacaccugg gagcccgagc     1020

agaagcucug caagcuccgc aagggcaacu gcuccuccac cgucugcggc caggaccucc     1080

agucccaccu cugcaugugc gccgagggcu acgcccucuc ccgcgaccgc aaguacugcg     1140

aggacgucaa cgagugcgcc uucuggaacc acggcugcac ccucggcugc aagaacaccc     1200

ccggcuccua cuacugcacc ugccccgucg gcuucguccu ccuccccgac ggcaagcgcu     1260

gccaccagcu cgucuccugc ccccgcaacg ucuccgagug cucccacgac ugcguccuca     1320

ccuccgaggg cccccucugc uucugccccg agggcuccgu ccucgagcgc gacggcaaga     1380

ccugcuccgg cugcuccucc cccgacaacg gcggcugcuc ccagcucugc gucccccucu     1440

cccccgucuc cugggagugc gacugcuucc ccggcuacga ccuccagcuc gacgagaagu     1500

ccugcgccgc cuccggcccc cagcccuucc uccucuucgc caacucccag gacauccgcc     1560

acaugcacuu cgacggcacc gacuacggca cccuccucuc ccagcagaug ggcauggucu     1620

acgcccucga ccacgacccc gucgagaaca agaucuacuu cgcccacacc gcccucaagu     1680

ggaucgagcg cgccaacaug gacggcuccc agcgcgagcg ccucaucgag gagggcgucg     1740

acguccccga gggccucgcc gucgacugga ucggccgccg cuucuacugg accgaccgcg     1800

gcaagucccu caucggccgc uccgaccuca acggcaagcg cuccaagauc aucaccaagg     1860

agaacaucuc ccagccccgc ggcaucgccg uccaccccau ggccaagcgc cucuucugga     1920

ccgacaccgg caucaacccc cgcaucgagu ccuccucccu ccagggccuc ggccgccucg     1980

ucaucgccuc cuccgaccuc aucuggcccu ccggcaucac caucgacuuc cucaccgaca     2040

agcucuacug gugcgacgcc aagcaguccg ucaucgagau ggccaaccuc gacggcucca     2100

agcgccgccg ccucacccag aacgacgucg gccaccccuu cgccgucgcc gucuucgagg     2160

acuacgucug guucuccgac ugggccaugc ccuccgucau gcgcgucaac aagcgcaccg     2220

gcaaggaccg cguccgccuc cagggcucca ugcucaagcc cuccucccuc gucgucgucc     2280

acccccucgc caagcccggc gccgaccccu gccucuacca gaacggcggc ugcgagcaca     2340

ucugcaagaa gcgccucggc accgccuggu gcuccugccg cgagggcuuc augaaggccu     2400

ccgacggcaa gaccugccuc gcccucgacg gccaccagcu ccucgccggc ggcgaggucg     2460

accucaagaa ccaggucacc ccccucgaca uccucuccaa gacccgcguc uccgaggaca     2520

acaucaccga gucccagcac augcucgucg ccgagaucau ggucuccgac caggacgacu     2580

gcgcccccgu cggcugcucc auguacgccc gcugcaucuc cgagggcgag gacgccaccu     2640

gccagugccu caagggcuuc gccggcgacg gcaagcucug cuccgacauc gacgagugcg     2700

agaugggcgu ccccgucugc ccccccgccu ccuccaagug caucaacacc gagggcggcu     2760

acgucugccg cugcuccgag ggcuaccagg gcgacggcau ccacugccuc gacaucgacg     2820

agugccagcu cggcgagcac uccugcggcg agaacgccuc cugcaccaac accgagggcg     2880

gcuacaccug caugugcgcc ggccgccucu ccgagcccgg ccucaucugc cccgacucca     2940

cccccccccc ccaccuccgc gaggacgacc accacuacuc cguccgcaac uccgacuccg     3000

agugcccccu cucccacgac ggcuacugcc uccacgacgg cgucugcaug uacaucgagg     3060

cccucgacaa guacgccugc aacugcgucg ucggcuacau cggcgagcgc ugccaguacc     3120

gcgaccucaa guggugggag cuccgccacg ccggccacgg ccagcagcag aaggucaucg     3180

ucgucgccgu cugcgucguc guccucguca ugcuccuccu ccucucccuc uggggcgccc     3240

acuacuaccg cacccagaag cuccucucca agaaccccaa gaaccccuac gaggaguccu     3300

cccgcgacgu ccgcucccgc cgccccgccg acaccgagga cggcaugucc uccugccccc     3360

agcccugguu cgucgucauc aaggagcacc aggaccucaa gaacggcggc cagcccgucg     3420

ccggcgagga cggccaggcc gccgacggcu ccaugcagcc caccuccugg cgccaggagc     3480

cccagcucug cggcaugggc accgagcagg gcugcuggau ccccgucucc uccgacaagg     3540

gcuccugccc ccaggucaug gagcgcuccu uccacaugcc cuccuacggc acccagaccc     3600

ucgagggcgg cgucgagaag ccccacuccc uccucuccgc caacccccuc uggcagcagc     3660

gcgcccucga ccccccccac cagauggagc ucacccagug aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  4034
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt2)

<400>  4034
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggcc gccgcaugga gaugcucugc gccggccgcg      120

uccccgcccu ccuccucugc cucggcuucc accuccucca ggccguccuc uccaccaccg      180

ucauccccuc cugcaucccc ggcgaguccu ccgacaacug caccgcccuc guccagaccg      240

aggacaaccc ccgcgucgcc caggucucca ucaccaagug cuccuccgac augaacggcu      300

acugccucca cggccagugc aucuaccucg ucgacauguc ccagaacuac ugccgcugcg      360

aggucggcua caccggcguc cgcugcgagc acuucuuccu caccguccac cagccccucu      420

ccaaggagua cgucgcccuc accgucaucc ucaucauccu cuuccucauc accgucgucg      480

gcuccaccua cuacuucugc cgcugguacc gcaaccgcaa guccaaggag cccaagaagg      540

aguacgagcg cgucaccucc ggcgaccccg agcuccccca ggucugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  4035
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt2)

<400>  4035
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgagggcg agaucaccac cuucaccgcc cucaccgaga      120

aguucaaccu cccccccggc aacuacaaga agcccaagcu ccucuacugc uccaacggcg      180

gccacuuccu ccgcauccuc cccgacggca ccgucgacgg cacccgcgac cgcuccgacc      240

agcacaucca gcuccagcuc uccgccgagu ccgucggcga ggucuacauc aaguccaccg      300

agaccggcca guaccucgcc auggacaccg acggccuccu cuacggcucc cagaccccca      360

acgaggagug ccucuuccuc gagcgccucg aggagaacca cuacaacacc uacaucucca      420

agaagcacgc cgagaagaac ugguucgucg gccucaagaa gaacggcucc ugcaagcgcg      480

gcccccgcac ccacuacggc cagaaggcca uccucuuccu cccccucccc gucuccuccg      540

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  4036
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt2)

<400>  4036
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucggcgucg gcggcggcga cgucgaggac gucacccccc      120

gccccggcgg cugccagauc uccggccgcg gcgcccgcgg cugcaacggc auccccggcg      180

ccgccgccug ggaggccgcc cucccccgcc gccgcccccg ccgccacccc uccgucaacc      240

cccgcucccg cgccgccggc uccccccgca cccgcggccg ccgcaccgag gagcgccccu      300

ccggcucccg ccucggcgac cgcggccgcg gccgcgcccu ccccggcggc cgccucggcg      360

gccgcggccg cggccgcgcc cccgagcgcg ucggcggccg cggccgcggc cgcggcaccg      420

ccgccccccg cgccgccccc gccgcccgcg gcucccgccc cggccccgcc ggcaccaugg      480

ccgccggcuc caucaccacc cuccccgccc uccccgagga cggcggcucc ggcgccuucc      540

cccccggcca cuucaaggac cccaagcgcc ucuacugcaa gaacggcggc uucuuccucc      600

gcauccaccc cgacggccgc gucgacggcg uccgcgagaa guccgacccc cacaucaagc      660

uccagcucca ggccgaggag cgcggcgucg ucuccaucaa gggcgucugc gccaaccgcu      720

accucgccau gaaggaggac ggccgccucc ucgccuccaa gugcgucacc gacgagugcu      780

ucuucuucga gcgccucgag uccaacaacu acaacaccua ccgcucccgc aaguacaccu      840

ccugguacgu cgcccucaag cgcaccggcc aguacaagcu cggcuccaag accggccccg      900

gccagaaggc cauccucuuc cuccccaugu ccgccaaguc cugaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  4037
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt2)

<400>  4037
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uccucaccug gauccucccc acccuccucu      120

accgcuccug cuuccacauc aucugccucg ucggcaccau cucccucgcc ugcaacgaca      180

ugacccccga gcagauggcc accaacguca acugcuccuc ccccgagcgc cacacccgcu      240

ccuacgacua cauggagggc ggcgacaucc gcguccgccg ccucuucugc cgcacccagu      300

gguaccuccg caucgacaag cgcggcaagg ucaagggcac ccaggagaug aagaacaacu      360

acaacaucau ggagauccgc accgucgccg ucggcaucgu cgccaucaag ggcgucgagu      420

ccgaguucua ccucgccaug aacaaggagg gcaagcucua cgccaagaag gagugcaacg      480

aggacugcaa cuucaaggag cucauccucg agaaccacua caacaccuac gccuccgcca      540

aguggaccca caacggcggc gagauguucg ucgcccucaa ccagaagggc auccccgucc      600

gcggcaagaa gaccaagaag gagcagaaga ccgcccacuu ccuccccaug gccaucaccu      660

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  4038
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt2)

<400>  4038
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcuccucc ccuccgucgu ccucaagcuc uuccucgccg      120

ccguccucuc cgcccucguc accggcgagu cccucgagcg ccuccgccgc ggccucgccg      180

ccggcaccuc caaccccgac ccccccaccg ucuccaccga ccagcuccuc ccccucggcg      240

gcggccgcga ccgcaagguc cgcgaccucc aggaggccga ccucgaccuc cuccgcguca      300

cccucuccuc caagccccag gcccucgcca cccccaacaa ggaggagcac ggcaagcgca      360

agaagaaggg caagggccuc ggcaagaagc gcgaccccug ccuccgcaag uacaaggacu      420

ucugcaucca cggcgagugc aaguacguca aggagcuccg cgcccccucc ugcaucugcc      480

accccggcua ccacggcgag cgcugccacg gccucucccu ccccgucgag aaccgccucu      540

acaccuacga ccacaccacc auccucgccg ucgucgccgu cguccucucc uccgucugcc      600

uccucgucau cgucggccuc cucauguucc gcuaccaccg ccgcggcggc uacgacgucg      660

agaacgagga gaaggucaag cucggcauga ccaacuccca cugaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  4039
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt2)

<400>  4039
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggucacca agcuccuccc cgcccuccuc cuccagcacg      120

uccuccucca ccuccuccuc cuccccaucg ccauccccua cgccgagggc cagcgcaagc      180

gccgcaacac cauccacgag uucaagaagu ccgccaagac cacccucauc aagaucgacc      240

ccgcccucaa gaucaagacc aagaagguca acaccgccga ccagugcgcc aaccgcugca      300

cccgcaacaa gggccucccc uucaccugca aggccuucgu cuucgacaag gcccgcaagc      360

agugccucug guuccccuuc aacuccaugu ccuccggcgu caagaaggag uucggccacg      420

aguucgaccu cuacgagaac aaggacuaca uccgcaacug caucaucggc aagggccgcu      480

ccuacaaggg caccgucucc aucaccaagu ccggcaucaa gugccagccc ugguccucca      540

ugauccccca cgagcacucc uuccuccccu ccuccuaccg cggcaaggac cuccaggaga      600

acuacugccg caacccccgc ggcgaggagg gcggccccug gugcuucacc uccaaccccg      660

agguccgcua cgaggucugc gacauccccc agugcuccga ggucgagugc augaccugca      720

acggcgaguc cuaccgcggc cucauggacc acaccgaguc cggcaagauc ugccagcgcu      780

gggaccacca gaccccccac cgccacaagu uccuccccga gcgcuacccc gacaagggcu      840

ucgacgacaa cuacugccgc aaccccgacg gccagccccg ccccuggugc uacacccucg      900

acccccacac ccgcugggag uacugcgcca ucaagaccug cgccgacaac accaugaacg      960

acaccgacgu cccccucgag accaccgagu gcauccaggg ccagggcgag ggcuaccgcg     1020

gcaccgucaa caccaucugg aacggcaucc ccugccagcg cugggacucc caguaccccc     1080

acgagcacga caugaccccc gagaacuuca agugcaagga ccuccgcgag aacuacugcc     1140

gcaaccccga cggcuccgag ucccccuggu gcuucaccac cgaccccaac auccgcgucg     1200

gcuacugcuc ccagaucccc aacugcgaca ugucccacgg ccaggacugc uaccgcggca     1260

acggcaagaa cuacaugggc aaccucuccc agacccgcuc cggccucacc ugcuccaugu     1320

gggacaagaa cauggaggac cuccaccgcc acaucuucug ggagcccgac gccuccaagc     1380

ucaacgagaa cuacugccgc aaccccgacg acgacgccca cggccccugg ugcuacaccg     1440

gcaacccccu cauccccugg gacuacugcc ccaucucccg cugcgagggc gacaccaccc     1500

ccaccaucgu caaccucgac caccccguca ucuccugcgc caagaccaag cagcuccgcg     1560

ucgucaacgg cauccccacc cgcaccaaca ucggcuggau ggucucccuc cgcuaccgca     1620

acaagcacau cugcggcggc ucccucauca aggaguccug gguccucacc gcccgccagu     1680

gcuuccccuc ccgcgaccuc aaggacuacg aggccuggcu cggcauccac gacguccacg     1740

gccgcggcga cgagaagugc aagcaggucc ucaacgucuc ccagcucguc uacggccccg     1800

agggcuccga ccucguccuc augaagcucg cccgccccgc cguccucgac gacuucgucu     1860

ccaccaucga ccuccccaac uacggcugca ccauccccga gaagaccucc ugcuccgucu     1920

acggcugggg cuacaccggc cucaucaacu acgacggccu ccuccgcguc gcccaccucu     1980

acaucauggg caacgagaag ugcucccagc accaccgcgg caaggucacc cucaacgagu     2040

ccgagaucug cgccggcgcc gagaagaucg gcuccggccc cugcgagggc gacuacggcg     2100

gcccccucgu cugcgagcag cacaagaugc gcaugguccu cggcgucauc guccccggcc     2160

gcggcugcgc cauccccaac cgccccggca ucuucguccg cgucgccuac uacgccaagu     2220

ggauccacaa gaucauccuc accuacaagg ucccccaguc cugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  4040
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt2)

<400>  4040
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggccg ccgccaucgg caucgaccuc ggcaccaccu      120

acuccugcgu cggcgucuuc cagcacggca aggucgagau caucgccaac gaccagggca      180

accgcaccac ccccuccuac gucgccuuca ccgacaccga gcgccucauc ggcgacgccg      240

ccaagaacca ggucgcccuc aacccccaga acaccgucuu cgacgccaag cgccucaucg      300

gccgcaaguu cggcgacccc gucguccagu ccgacaugaa gcacuggccc uuccagguca      360

ucaacgacgg cgacaagccc aagguccagg ucuccuacaa gggcgagacc aaggccuucu      420

accccgagga gaucuccucc augguccuca ccaagaugaa ggagaucgcc gaggccuacc      480

ucggcuaccc cgucaccaac gccgucauca ccguccccgc cuacuucaac gacucccagc      540

gccaggccac caaggacgcc ggcgucaucg ccggccucaa cguccuccgc aucaucaacg      600

agcccaccgc cgccgccauc gccuacggcc ucgaccgcac cggcaagggc gagcgcaacg      660

uccucaucuu cgaccucggc ggcggcaccu ucgacgucuc cauccucacc aucgacgacg      720

gcaucuucga ggucaaggcc accgccggcg acacccaccu cggcggcgag gacuucgaca      780

accgccucgu caaccacuuc gucgaggagu ucaagcgcaa gcacaagaag gacaucuccc      840

agaacaagcg cgccguccgc cgccuccgca ccgccugcga gcgcgccaag cgcacccucu      900

ccuccuccac ccaggccucc cucgagaucg acucccucuu cgagggcauc gacuucuaca      960

ccuccaucac ccgcgcccgc uucgaggagc ucugcuccga ccucuuccgc uccacccucg     1020

agcccgucga gaaggcccuc cgcgacgcca agcucgacaa ggcccagauc cacgaccucg     1080

uccucgucgg cggcuccacc cgcaucccca agguccagaa gcuccuccag gacuucuuca     1140

acggccgcga ccucaacaag uccaucaacc ccgacgaggc cgucgccuac ggcgccgccg     1200

uccaggccgc cauccucaug ggcgacaagu ccgagaacgu ccaggaccuc cuccuccucg     1260

acgucgcccc ccucucccuc ggccucgaga ccgccggcgg cgucaugacc gcccucauca     1320

agcgcaacuc caccaucccc accaagcaga cccagaucuu caccaccuac uccgacaacc     1380

agcccggcgu ccucauccag gucuacgagg gcgagcgcgc caugaccaag gacaacaacc     1440

uccucggccg cuucgagcuc uccggcaucc cccccgcccc ccgcggcguc ccccagaucg     1500

aggucaccuu cgacaucgac gccaacggca uccucaacgu caccgccacc gacaagucca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg ccgccucucc aaggaggaga     1620

ucgagcgcau gguccaggag gccgagaagu acaaggccga ggacgagguc cagcgcgagc     1680

gcgucuccgc caagaacgcc cucgaguccu acgccuucaa caugaagucc gccgucgagg     1740

acgagggccu caagggcaag aucuccgagg ccgacaagaa gaagguccuc gacaagugcc     1800

aggaggucau cuccuggcuc gacgccaaca cccucgccga gaaggacgag uucgagcaca     1860

agcgcaagga gcucgagcag gucugcaacc ccaucaucuc cggccucuac cagggcgccg     1920

gcggccccgg ccccggcggc uucggcgccc agggccccaa gggcggcucc ggcuccggcc     1980

ccaccaucga ggaggucgac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4041
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt2)

<400>  4041
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggccg ccgccaucgg caucgaccuc ggcaccaccu      120

acuccugcgu cggcgucuuc cagcacggca aggucgagau caucgccaac gaccagggca      180

accgcaccac ccccuccuac gucgccuuca ccgacaccga gcgccucauc ggcgacgccg      240

ccaagaacca ggucgcccuc aacccccaga acaccgucuu cgacgccaag cgccucaucg      300

gccgcaaguu cggcgacccc gucguccagu ccgacaugaa gcacuggccc uuccagguca      360

ucaacgacgg cgacaagccc aagguccagg ucuccuacaa gggcgagacc aaggccuucu      420

accccgagga gaucuccucc augguccuca ccaagaugaa ggagaucgcc gaggccuacc      480

ucggcuaccc cgucaccaac gccgucauca ccguccccgc cuacuucaac gacucccagc      540

gccaggccac caaggacgcc ggcgucaucg ccggccucaa cguccuccgc aucaucaacg      600

agcccaccgc cgccgccauc gccuacggcc ucgaccgcac cggcaagggc gagcgcaacg      660

uccucaucuu cgaccucggc ggcggcaccu ucgacgucuc cauccucacc aucgacgacg      720

gcaucuucga ggucaaggcc accgccggcg acacccaccu cggcggcgag gacuucgaca      780

accgccucgu caaccacuuc gucgaggagu ucaagcgcaa gcacaagaag gacaucuccc      840

agaacaagcg cgccguccgc cgccuccgca ccgccugcga gcgcgccaag cgcacccucu      900

ccuccuccac ccaggccucc cucgagaucg acucccucuu cgagggcauc gacuucuaca      960

ccuccaucac ccgcgcccgc uucgaggagc ucugcuccga ccucuuccgc uccacccucg     1020

agcccgucga gaaggcccuc cgcgacgcca agcucgacaa ggcccagauc cacgaccucg     1080

uccucgucgg cggcuccacc cgcaucccca agguccagaa gcuccuccag gacuucuuca     1140

acggccgcga ccucaacaag uccaucaacc ccgacgaggc cgucgccuac ggcgccgccg     1200

uccaggccgc cauccucaug ggcgacaagu ccgagaacgu ccaggaccuc cuccuccucg     1260

acgucgcccc ccucucccuc ggccucgaga ccgccggcgg cgucaugacc gcccucauca     1320

agcgcaacuc caccaucccc accaagcaga cccagaucuu caccaccuac uccgacaacc     1380

agcccggcgu ccucauccag gucuacgagg gcgagcgcgc caugaccaag gacaacaacc     1440

uccucggccg cuucgagcuc uccggcaucc cccccgcccc ccgcggcguc ccccagaucg     1500

aggucaccuu cgacaucgac gccaacggca uccucaacgu caccgccacc gacaagucca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg ccgccucucc aaggaggaga     1620

ucgagcgcau gguccaggag gccgagaagu acaaggccga ggacgagguc cagcgcgagc     1680

gcgucuccgc caagaacgcc cucgaguccu acgccuucaa caugaagucc gccgucgagg     1740

acgagggccu caagggcaag aucuccgagg ccgacaagaa gaagguccuc gacaagugcc     1800

aggaggucau cuccuggcuc gacgccaaca cccucgccga gaaggacgag uucgagcaca     1860

agcgcaagga gcucgagcag gucugcaacc ccaucaucuc cggccucuac cagggcgccg     1920

gcggccccgg ccccggcggc uucggcgccc agggccccaa gggcggcucc ggcuccggcc     1980

ccaccaucga ggaggucgac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4042
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt2)

<400>  4042
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaccgcca agggcaucgc caucggcauc gaccucggca      120

ccaccuacuc cugcgucggc gucuuccagc acggcaaggu cgagaucauc gccaacgacc      180

agggcaaccg caccaccccc uccuacgucg ccuucaccga caccgagcgc cucaucggcg      240

acgccgccaa gaaccagguc gccaugaacc cccagaacac cgucuucgac gccaagcgcc      300

ucaucggccg caaguucaac gaccccgucg uccaggccga caugaagcuc uggcccuucc      360

aggucaucaa cgagggcggc aagcccaagg uccucgucuc cuacaagggc gagaacaagg      420

ccuucuaccc cgaggagauc uccuccaugg uccucaccaa gcucaaggag accgccgagg      480

ccuuccucgg ccaccccguc accaacgccg ucaucaccgu ccccgccuac uucaacgacu      540

cccagcgcca ggccaccaag gacgccggcg ucaucgccgg ccucaacguc cuccgcauca      600

ucaacgagcc caccgccgcc gccaucgccu acggccucga caagggcggc cagggcgagc      660

gccacguccu caucuucgac cucggcggcg gcaccuucga cgucuccauc cucaccaucg      720

acgacggcau cuucgagguc aaggccaccg ccggcgacac ccaccucggc ggcgaggacu      780

ucgacaaccg ccucgucucc cacuucgucg aggaguucaa gcgcaagcac aagaaggaca      840

ucucccagaa caagcgcgcc guccgccgcc uccgcaccgc cugcgagcgc gccaagcgca      900

cccucuccuc cuccacccag gccaaccucg agaucgacuc ccucuacgag ggcaucgacu      960

ucuacaccuc caucacccgc gcccgcuucg aggagcucug cgccgaccuc uuccgcggca     1020

cccucgagcc cgucgagaag gcccuccgcg acgccaagau ggacaaggcc aagauccacg     1080

acaucguccu cgucggcggc uccacccgca uccccaaggu ccagcgccuc cuccaggacu     1140

acuucaacgg ccgcgaccuc aacaagucca ucaaccccga cgaggccguc gccuacggcg     1200

ccgccgucca ggccgccauc cucaugggcg acaaguccga gaagguccag gaccuccucc     1260

uccucgacgu cgccccccuc ucccucggcc ucgagaccgc cggcggcguc augaccgccc     1320

ucaucaagcg caacuccacc auccccacca agcagaccca gaucuucacc accuacuccg     1380

acaaccagcc cggcguccuc auccaggucu acgagggcga gcgcgccaug accaaggaca     1440

acaaccuccu cggccgcuuc gaccucaccg gcaucccccc cgccccccgc ggcguccccc     1500

agaucgaggu caccuucgac aucgacgcca acggcauccu caacgucacc gccaccgaca     1560

aguccaccgg caaggucaac aagaucacca ucaccaacga caagggccgc cucuccaagg     1620

aggagaucga gcgcaugguc cucgacgccg agaaguacaa ggccgaggac gagguccagc     1680

gcgagaagau cgccgccaag aacgcccucg aguccuacgc cuucaacaug aaguccgucg     1740

ucuccgacga gggccucaag ggcaagaucu ccgaguccga caagaacaag auccucgaca     1800

agugcaacga gcuccucucc uggcucgagg ucaaccagcu cgccgagaag gacgaguucg     1860

accacaagcg caaggagcuc gagcagaugu gcaaccccau caucaccaag cucuaccagg     1920

gcggcugcac cggccccgcc ugcggcaccg gcuacguccc cggccgcccc gccaccggcc     1980

ccaccaucga ggaggucgac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4043
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt2)

<400>  4043
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgcccgcg gccccgccau cggcaucgac cucggcacca      120

ccuacuccug cgucggcguc uuccagcacg gcaaggucga gaucaucgcc aacgaccagg      180

gcaaccgcac cacccccucc uacgucgccu ucaccgacac cgagcgccuc aucggcgacg      240

ccgccaagaa ccaggucgcc augaacccca ccaacaccau cuucgacgcc aagcgccuca      300

ucggccgcaa guucgaggac gccaccgucc aguccgacau gaagcacugg cccuuccgcg      360

ucgucuccga gggcggcaag cccaaggucc aggucgagua caagggcgag accaagaccu      420

ucuuccccga ggagaucucc uccauggucc ucaccaagau gaaggagauc gccgaggccu      480

accucggcgg caagguccac uccgccguca ucaccguccc cgccuacuuc aacgacuccc      540

agcgccaggc caccaaggac gccggcacca ucaccggccu caacguccuc cgcaucauca      600

acgagcccac cgccgccgcc aucgccuacg gccucgacaa gaagggcugc gccggcggcg      660

agaagaacgu ccucaucuuc gaccucggcg gcggcaccuu cgacgucucc auccucacca      720

ucgaggacgg caucuucgag gucaagucca ccgccggcga cacccaccuc ggcggcgagg      780

acuucgacaa ccgcaugguc ucccaccucg ccgaggaguu caagcgcaag cacaagaagg      840

acaucggccc caacaagcgc gccguccgcc gccuccgcac cgccugcgag cgcgccaagc      900

gcacccucuc cuccuccacc caggccucca ucgagaucga cucccucuac gagggcgucg      960

acuucuacac cuccaucacc cgcgcccgcu ucgaggagcu caacgccgac cucuuccgcg     1020

gcacccucga gcccgucgag aaggcccucc gcgacgccaa gcucgacaag ggccagaucc     1080

aggagaucgu ccucgucggc ggcuccaccc gcauccccaa gauccagaag cuccuccagg     1140

acuucuucaa cggcaaggag cucaacaagu ccaucaaccc cgacgaggcc gucgccuacg     1200

gcgccgccgu ccaggccgcc auccucaucg gcgacaaguc cgagaacguc caggaccucc     1260

uccuccucga cgucaccccc cucucccucg gcaucgagac cgccggcggc gucaugaccc     1320

cccucaucaa gcgcaacacc accaucccca ccaagcagac ccagaccuuc accaccuacu     1380

ccgacaacca guccuccguc cucguccagg ucuacgaggg cgagcgcgcc augaccaagg     1440

acaacaaccu ccucggcaag uucgaccuca ccggcauccc ccccgccccc cgcggcgucc     1500

cccagaucga ggucaccuuc gacaucgacg ccaacggcau ccucaacguc accgccgccg     1560

acaaguccac cggcaaggag aacaagauca ccaucaccaa cgacaagggc cgccucucca     1620

aggacgacau cgaccgcaug guccaggagg ccgagcgcua caaguccgag gacgaggcca     1680

accgcgaccg cgucgccgcc aagaacgccc ucgaguccua caccuacaac aucaagcaga     1740

ccgucgagga cgagaagcuc cgcggcaaga ucuccgagca ggacaagaac aagauccucg     1800

acaagugcca ggaggucauc aacuggcucg accgcaacca gauggccgag aaggacgagu     1860

acgagcacaa gcagaaggag cucgagcgcg ucugcaaccc caucaucucc aagcucuacc     1920

agggcggccc cggcggcggc uccggcggcg gcggcuccgg cgccuccggc ggccccacca     1980

ucgaggaggu cgacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  4044
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt2)

<400>  4044
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgucgucg gcaucgaccu cggcuuccag uccugcuacg      120

ucgccgucgc ccgcgccggc ggcaucgaga ccaucgccaa cgaguacucc gaccgcugca      180

cccccgccug caucuccuuc ggccccaaga accgcuccau cggcgccgcc gccaaguccc      240

aggucaucuc caacgccaag aacaccgucc agggcuucaa gcgcuuccac ggccgcgccu      300

ucuccgaccc cuucgucgag gccgagaagu ccaaccucgc cuacgacauc guccagcucc      360

ccaccggccu caccggcauc aaggucaccu acauggagga ggagcgcaac uucaccaccg      420

agcaggucac cgccaugcuc cucuccaagc ucaaggagac cgccgagucc guccucaaga      480

agcccgucgu cgacugcguc gucuccgucc ccugcuucua caccgacgcc gagcgccgcu      540

ccgucaugga cgccacccag aucgccggcc ucaacugccu ccgccucaug aacgagacca      600

ccgccgucgc ccucgccuac ggcaucuaca agcaggaccu ccccgcccuc gaggagaagc      660

cccgcaacgu cgucuucguc gacaugggcc acuccgccua ccaggucucc gucugcgccu      720

ucaaccgcgg caagcucaag guccucgcca ccgccuucga caccacccuc ggcggccgca      780

aguucgacga gguccucguc aaccacuucu gcgaggaguu cggcaagaag uacaagcucg      840

acaucaaguc caagauccgc gcccuccucc gccucuccca ggagugcgag aagcucaaga      900

agcucauguc cgccaacgcc uccgaccucc cccucuccau cgagugcuuc augaacgacg      960

ucgacgucuc cggcaccaug aaccgcggca aguuccucga gaugugcaac gaccuccucg     1020

cccgcgucga gcccccccuc cgcuccgucc ucgagcagac caagcucaag aaggaggaca     1080

ucuacgccgu cgagaucguc ggcggcgcca cccgcauccc cgccgucaag gagaagaucu     1140

ccaaguucuu cggcaaggag cucuccacca cccucaacgc cgacgaggcc gucacccgcg     1200

gcugcgcccu ccagugcgcc auccucuccc ccgccuucaa gguccgcgag uucuccauca     1260

ccgacgucgu ccccuacccc aucucccucc gcuggaacuc ccccgccgag gagggcuccu     1320

ccgacugcga ggucuucucc aagaaccacg ccgcccccuu cuccaagguc cucaccuucu     1380

accgcaagga gcccuucacc cucgaggccu acuacuccuc cccccaggac cuccccuacc     1440

ccgaccccgc caucgcccag uucuccgucc agaaggucac cccccagucc gacggcuccu     1500

ccuccaaggu caaggucaag guccgcguca acguccacgg caucuucucc gucuccuccg     1560

ccucccucgu cgagguccac aaguccgagg agaacgagga gcccauggag accgaccaga     1620

acgccaagga ggaggagaag augcaggucg accaggagga gccccacguc gaggagcagc     1680

agcagcagac ccccgccgag aacaaggccg aguccgagga gauggagacc ucccaggccg     1740

gcuccaagga caagaagaug gaccagcccc cccaggccaa gaaggccaag gucaagaccu     1800

ccaccgucga ccuccccauc gagaaccagc uccucuggca gaucgaccgc gagaugcuca     1860

accucuacau cgagaacgag ggcaagauga ucaugcagga caagcucgag aaggagcgca     1920

acgacgccaa gaacgccguc gaggaguacg ucuacgagau gcgcgacaag cucuccggcg     1980

aguacgagaa guucgucucc gaggacgacc gcaacuccuu cacccucaag cucgaggaca     2040

ccgagaacug gcucuacgag gacggcgagg accagcccaa gcaggucuac gucgacaagc     2100

ucgccgagcu caagaaccuc ggccagccca ucaagauccg cuuccaggag uccgaggagc     2160

gccccaagcu cuucgaggag cucggcaagc agauccagca guacaugaag aucaucuccu     2220

ccuucaagaa caaggaggac caguacgacc accucgacgc cgccgacaug accaaggucg     2280

agaaguccac caacgaggcc auggagugga ugaacaacaa gcucaaccuc cagaacaagc     2340

agucccucac cauggacccc gucgucaagu ccaaggagau cgaggccaag aucaaggagc     2400

ucaccuccac cugcuccccc aucaucucca agcccaagcc caaggucgag ccccccaagg     2460

aggagcagaa gaacgccgag cagaacggcc ccgucgacgg ccagggcgac aaccccggcc     2520

cccaggccgc cgagcagggc accgacaccg ccguccccuc cgacuccgac aagaagcucc     2580

ccgagaugga caucgacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  4045
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt2)

<400>  4045
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgucgucg gcaucgaccu cggcuuccuc aacugcuaca      120

ucgccgucgc ccgcuccggc ggcaucgaga ccaucgccaa cgaguacucc gaccgcugca      180

cccccgccug caucucccuc ggcucccgca cccgcgccau cggcaacgcc gccaaguccc      240

agaucgucac caacguccgc aacaccaucc acggcuucaa gaagcuccac ggccgcuccu      300

ucgacgaccc caucguccag accgagcgca uccgccuccc cuacgagcuc cagaagaugc      360

ccaacggcuc cgccggcguc aagguccgcu accucgagga ggagcgcccc uucgccaucg      420

agcaggucac cggcaugcuc cucgccaagc ucaaggagac cuccgagaac gcccucaaga      480

agcccgucgc cgacugcguc aucuccaucc ccuccuucuu caccgacgcc gagcgccgcu      540

ccgucauggc cgccgcccag gucgccggcc ucaacugccu ccgccucaug aacgagacca      600

ccgccgucgc ccucgccuac ggcaucuaca agcaggaccu ccccccccuc gacgagaagc      660

cccgcaacgu cgucuucauc gacaugggcc acuccgccua ccagguccuc gucugcgccu      720

ucaacaaggg caagcucaag guccucgcca ccaccuucga ccccuaccuc ggcggccgca      780

acuucgacga ggcccucguc gacuacuucu gcgacgaguu caagaccaag uacaagauca      840

acgucaagga gaacucccgc gcccuccucc gccucuacca ggagugcgag aagcucaaga      900

agcucauguc cgccaacgcc uccgaccucc cccucaacau cgagugcuuc augaacgacc      960

ucgacgucuc cuccaagaug aaccgcgccc aguucgagca gcucugcgcc ucccuccucg     1020

cccgcgucga gcccccccuc aaggccguca uggagcaggc caaccuccag cgcgaggaca     1080

ucuccuccau cgagaucguc ggcggcgcca cccgcauccc cgccgucaag gagcagauca     1140

ccaaguucuu ccucaaggac aucuccacca cccucaacgc cgacgaggcc gucgcccgcg     1200

gcugcgcccu ccagugcgcc auccucuccc ccgccuucaa gguccgcgag uucuccauca     1260

ccgaccucgu ccccuacucc aucacccucc gcuggaagac cuccuucgag gacggcuccg     1320

gcgagugcga ggucuucugc aagaaccacc ccgcccccuu cuccaagguc aucaccuucc     1380

acaagaagga gcccuucgag cucgaggccu ucuacaccaa ccuccacgag guccccuacc     1440

ccgacgcccg caucggcucc uucaccaucc agaacgucuu cccccagucc gacggcgacu     1500

ccuccaaggu caaggucaag guccgcguca acauccacgg caucuucucc gucgccuccg     1560

ccuccgucau cgagaagcag aaccucgagg gcgaccacuc cgacgccccc auggagaccg     1620

agaccuccuu caagaacgag aacaaggaca acauggacaa gaugcagguc gaccaggagg     1680

agggccacca gaagugccac gccgagcaca cccccgagga ggagaucgac cacaccggcg     1740

ccaagaccaa guccgccguc uccgacaagc aggaccgccu caaccagacc cucaagaagg     1800

gcaaggucaa guccaucgac cuccccaucc aguccucccu cugccgccag cucggccagg     1860

accuccucaa cuccuacauc gagaacgagg gcaagaugau caugcaggac aagcucgaga     1920

aggagcgcaa cgacgccaag aacgccgucg aggaguacgu cuacgacuuc cgcgaccgcc     1980

ucggcaccgu cuacgagaag uucaucaccc ccgaggaccu cuccaagcuc uccgccgucc     2040

ucgaggacac cgagaacugg cucuacgagg acggcgagga ccagcccaag caggucuacg     2100

ucgacaagcu ccaggagcuc aagaaguacg gccagcccau ccagaugaag uacauggagc     2160

acgaggagcg ccccaaggcc cucaacgacc ucggcaagaa gauccagcuc gucaugaagg     2220

ucaucgaggc cuaccgcaac aaggacgagc gcuacgacca ccucgacccc accgagaugg     2280

agaaggucga gaagugcauc uccgacgcca uguccuggcu caacuccaag augaacgccc     2340

agaacaagcu cucccucacc caggaccccg ucgucaaggu cuccgagauc gucgccaagu     2400

ccaaggagcu cgacaacuuc ugcaacccca ucaucuacaa gcccaagccc aaggccgagg     2460

uccccgagga caagcccaag gccaacuccg agcacaacgg ccccauggac ggccaguccg     2520

gcaccgagac caaguccgac uccaccaagg acuccuccca gcacaccaag uccuccggcg     2580

agauggaggu cgacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  4046
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt2)

<400>  4046
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcucuccc ucgucgccgc caugcuccuc cuccucuccg      120

ccgcccgcgc cgaggaggag gacaagaagg aggacgucgg caccgucguc ggcaucgacc      180

ucggcaccac cuacuccugc gucggcgucu ucaagaacgg ccgcgucgag aucaucgcca      240

acgaccaggg caaccgcauc acccccuccu acgucgccuu cacccccgag ggcgagcgcc      300

ucaucggcga cgccgccaag aaccagcuca ccuccaaccc cgagaacacc gucuucgacg      360

ccaagcgccu caucggccgc accuggaacg accccuccgu ccagcaggac aucaaguucc      420

uccccuucaa ggucgucgag aagaagacca agcccuacau ccaggucgac aucggcggcg      480

gccagaccaa gaccuucgcc cccgaggaga ucuccgccau gguccucacc aagaugaagg      540

agaccgccga ggccuaccuc ggcaagaagg ucacccacgc cgucgucacc guccccgccu      600

acuucaacga cgcccagcgc caggccacca aggacgccgg caccaucgcc ggccucaacg      660

ucaugcgcau caucaacgag cccaccgccg ccgccaucgc cuacggccuc gacaagcgcg      720

agggcgagaa gaacauccuc gucuucgacc ucggcggcgg caccuucgac gucucccucc      780

ucaccaucga caacggcguc uucgaggucg ucgccaccaa cggcgacacc caccucggcg      840

gcgaggacuu cgaccagcgc gucauggagc acuucaucaa gcucuacaag aagaagaccg      900

gcaaggacgu ccgcaaggac aaccgcgccg uccagaagcu ccgccgcgag gucgagaagg      960

ccaagcgcgc ccucuccucc cagcaccagg cccgcaucga gaucgagucc uucuacgagg     1020

gcgaggacuu cuccgagacc cucacccgcg ccaaguucga ggagcucaac auggaccucu     1080

uccgcuccac caugaagccc guccagaagg uccucgagga cuccgaccuc aagaaguccg     1140

acaucgacga gaucguccuc gucggcggcu ccacccgcau ccccaagauc cagcagcucg     1200

ucaaggaguu cuucaacggc aaggagcccu cccgcggcau caaccccgac gaggccgucg     1260

ccuacggcgc cgccguccag gccggcgucc ucuccggcga ccaggacacc ggcgaccucg     1320

uccuccucga cgucugcccc cucacccucg gcaucgagac cgucggcggc gucaugacca     1380

agcucauccc ccgcaacacc gucgucccca ccaagaaguc ccagaucuuc uccaccgccu     1440

ccgacaacca gcccaccguc accaucaagg ucuacgaggg cgagcgcccc cucaccaagg     1500

acaaccaccu ccucggcacc uucgaccuca ccggcauccc ccccgccccc cgcggcgucc     1560

cccagaucga ggucaccuuc gagaucgacg ucaacggcau ccuccgcguc accgccgagg     1620

acaagggcac cggcaacaag aacaagauca ccaucaccaa cgaccagaac cgccucaccc     1680

ccgaggagau cgagcgcaug gucaacgacg ccgagaaguu cgccgaggag gacaagaagc     1740

ucaaggagcg caucgacacc cgcaacgagc ucgaguccua cgccuacucc cucaagaacc     1800

agaucggcga caaggagaag cucggcggca agcucuccuc cgaggacaag gagaccaugg     1860

agaaggccgu cgaggagaag aucgaguggc ucgaguccca ccaggacgcc gacaucgagg     1920

acuucaaggc caagaagaag gagcucgagg agaucgucca gcccaucauc uccaagcucu     1980

acggcuccgc cggccccccc cccaccggcg aggaggacac cgccgagaag gacgagcucu     2040

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  4047
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt2)

<400>  4047
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggcccccc gcgagcucgc cgucggcauc gaccucggca      120

ccaccuacuc cugcgucggc gucuuccagc agggccgcgu cgagauccuc gccaacgacc      180

agggcaaccg caccaccccc uccuacgucg ccuucaccga caccgagcgc cucgucggcg      240

acgccgccaa gucccaggcc gcccucaacc cccacaacac cgucuucgac gccaagcgcc      300

ucaucggccg caaguucgcc gacaccaccg uccaguccga caugaagcac uggcccuucc      360

gcgucgucuc cgagggcggc aagcccaagg uccgcgucug cuaccgcggc gaggacaaga      420

ccuucuaccc cgaggagauc uccuccaugg uccucuccaa gaugaaggag accgccgagg      480

ccuaccucgg ccagcccguc aagcacgccg ucaucaccgu ccccgccuac uucaacgacu      540

cccagcgcca ggccaccaag gacgccggcg ccaucgccgg ccucaacguc cuccgcauca      600

ucaacgagcc caccgccgcc gccaucgccu acggccucga ccgccgcggc gccggcgagc      660

gcaacguccu caucuucgac cucggcggcg gcaccuucga cgucuccguc cucuccaucg      720

acgccggcgu cuucgagguc aaggccaccg ccggcgacac ccaccucggc ggcgaggacu      780

ucgacaaccg ccucgucaac cacuucaugg aggaguuccg ccgcaagcac ggcaaggacc      840

ucuccggcaa caagcgcgcc cuccgccgcc uccgcaccgc cugcgagcgc gccaagcgca      900

cccucuccuc cuccacccag gccacccucg agaucgacuc ccucuucgag ggcgucgacu      960

ucuacaccuc caucacccgc gcccgcuucg aggagcucug cuccgaccuc uuccgcucca     1020

cccucgagcc cgucgagaag gcccuccgcg acgccaagcu cgacaaggcc cagauccacg     1080

acgucguccu cgucggcggc uccacccgca uccccaaggu ccagaagcuc cuccaggacu     1140

ucuucaacgg caaggagcuc aacaagucca ucaaccccga cgaggccguc gccuacggcg     1200

ccgccgucca ggccgccguc cucaugggcg acaagugcga gaagguccag gaccuccucc     1260

uccucgacgu cgccccccuc ucccucggcc ucgagaccgc cggcggcguc augaccaccc     1320

ucauccagcg caacgccacc auccccacca agcagaccca gaccuucacc accuacuccg     1380

acaaccagcc cggcgucuuc auccaggucu acgagggcga gcgcgccaug accaaggaca     1440

acaaccuccu cggccgcuuc gagcucuccg gcaucccccc cgccccccgc ggcguccccc     1500

agaucgaggu caccuucgac aucgacgcca acggcauccu cuccgucacc gccaccgacc     1560

gcuccaccgg caaggccaac aagaucacca ucaccaacga caagggccgc cucuccaagg     1620

aggaggucga gcgcaugguc cacgaggccg agcaguacaa ggccgaggac gaggcccagc     1680

gcgaccgcgu cgccgccaag aacucccucg aggcccacgu cuuccacguc aagggcuccc     1740

uccaggagga gucccuccgc gacaagaucc ccgaggagga ccgccgcaag augcaggaca     1800

agugccgcga gguccucgcc uggcucgagc acaaccagcu cgccgagaag gaggaguacg     1860

agcaccagaa gcgcgagcuc gagcagaucu gccgccccau cuucucccgc cucuacggcg     1920

gccccggcgu ccccggcggc uccuccugcg gcacccaggc ccgccagggc gaccccucca     1980

ccggccccau caucgaggag gucgacugag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  4048
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt2)

<400>  4048
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggcccccc gcgagcucgc cgucggcauc gaccucggca      120

ccaccuacuc cugcgucggc gucuuccagc agggccgcgu cgagauccuc gccaacgacc      180

agggcaaccg caccaccccc uccuacgucg ccuucaccga caccgagcgc cucgucggcg      240

acgccgccaa gucccaggcc gcccucaacc cccacaacac cgucuucgac gccaagcgcc      300

ucaucggccg caaguucgcc gacaccaccg uccaguccga caugaagcac uggcccuucc      360

aggucgucuc cgagggcggc aagcccaagg uccgcgucug cuaccgcggc gaggacaaga      420

ccuucuaccc cgaggagauc uccuccaugg uccucuccaa gaugaaggag accgccgagg      480

ccuaccucgg ccagcccguc aagcacgccg ucaucaccgu ccccaccuac uucuccaacu      540

cccagcgcca ggccaccaag gacgccggcg ccaucgccgg ccucaagguc cuccccauca      600

ucaacgaggc caccgccgcc gccaucgccu acggccucga ccgccgcggc gccggcaagc      660

gcaacguccu caucuucgac cucggcggcg gcaccuucga cgucuccguc cucuccaucg      720

acgccggcgu cuucgagguc aaggccaccg ccggcgacac ccaccucggc ggcgaggacu      780

ucgacaaccg ccucgucaac cacuucaugg aggaguuccg ccgcaagcac ggcaaggacc      840

ucuccggcaa caagcgcgcc cuccgccgcc uccgcaccgc cugcgagcgc gccaagcgca      900

cccccuccuc cuccacccag gccacccucg agaucgacuc ccucuucgag ggcgucgacu      960

ucuacaaguc caucacccgc gcccgcuucg aggagcucug cuccgaccuc uuccgcucca     1020

cccucgagcc cgucgagaag gcccuccgcg acgccaagcu cgacaaggcc cagauccacg     1080

acuucguccu cggcggcggc cuccacuccc acccccaggg cgccgagguc gccgccggcc     1140

uccuccagcg ccagggcgcc gagcaggagc accagcccug aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  4049
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt2)

<400>  4049
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccaagggcc ccgccgucgg caucgaccuc ggcaccaccu      120

acuccugcgu cggcgucuuc cagcacggca aggucgagau caucgccaac gaccagggca      180

accgcaccac ccccuccuac gucgccuuca ccgacaccga gcgccucauc ggcgacgccg      240

ccaagaacca ggucgccaug aaccccacca acaccgucuu cgacgccaag cgccucaucg      300

gccgccgcuu cgacgacgcc gucguccagu ccgacaugaa gcacuggccc uucauggucg      360

ucaacgacgc cggccgcccc aagguccagg ucgaguacaa gggcgagacc aaguccuucu      420

accccgagga ggucuccucc augguccuca ccaagaugaa ggagaucgcc gaggccuacc      480

ucggcaagac cgucaccaac gccgucguca ccguccccgc cuacuucaac gacucccagc      540

gccaggccac caaggacgcc ggcaccaucg ccggccucaa cguccuccgc aucaucaacg      600

agcccaccgc cgccgccauc gccuacggcc ucgacaagaa ggucggcgcc gagcgcaacg      660

uccucaucuu cgaccucggc ggcggcaccu ucgacgucuc cauccucacc aucgaggacg      720

gcaucuucga ggucaagucc accgccggcg acacccaccu cggcggcgag gacuucgaca      780

accgcauggu caaccacuuc aucgccgagu ucaagcgcaa gcacaagaag gacaucuccg      840

agaacaagcg cgccguccgc cgccuccgca ccgccugcga gcgcgccaag cgcacccucu      900

ccuccuccac ccaggccucc aucgagaucg acucccucua cgagggcauc gacuucuaca      960

ccuccaucac ccgcgcccgc uucgaggagc ucaacgccga ccucuuccgc ggcacccucg     1020

accccgucga gaaggcccuc cgcgacgcca agcucgacaa gucccagauc cacgacaucg     1080

uccucgucgg cggcuccacc cgcaucccca agauccagaa gcuccuccag gacuucuuca     1140

acggcaagga gcucaacaag uccaucaacc ccgacgaggc cgucgccuac ggcgccgccg     1200

uccaggccgc cauccucucc ggcgacaagu ccgagaacgu ccaggaccuc cuccuccucg     1260

acgucacccc ccucucccuc ggcaucgaga ccgccggcgg cgucaugacc guccucauca     1320

agcgcaacac caccaucccc accaagcaga cccagaccuu caccaccuac uccgacaacc     1380

agcccggcgu ccucauccag gucuacgagg gcgagcgcgc caugaccaag gacaacaacc     1440

uccucggcaa guucgagcuc accggcaucc cccccgcccc ccgcggcguc ccccagaucg     1500

aggucaccuu cgacaucgac gccaacggca uccucaacgu cuccgccguc gacaagucca     1560

ccggcaagga gaacaagauc accaucacca acgacaaggg ccgccucucc aaggaggaca     1620

ucgagcgcau gguccaggag gccgagaagu acaaggccga ggacgagaag cagcgcgaca     1680

aggucuccuc caagaacucc cucgaguccu acgccuucaa caugaaggcc accgucgagg     1740

acgagaagcu ccagggcaag aucaacgacg aggacaagca gaagauccuc gacaagugca     1800

acgagaucau caacuggcuc gacaagaacc agaccgccga gaaggaggag uucgagcacc     1860

agcagaagga gcucgagaag gucugcaacc ccaucaucac caagcucuac caguccgccg     1920

gcggcaugcc cggcggcaug cccggcggcu uccccggcgg cggcgccccc cccuccggcg     1980

gcgccuccuc cggccccacc aucgaggagg ucgacugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  4050
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt2)

<400>  4050
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucuccgccu cccgcgccgc cgccgcccgc cucgucggcg      120

ccgccgccuc ccgcggcccc accgccgccc gccaccagga cuccuggaac ggccucuccc      180

acgaggccuu ccgccucguc ucccgccgcg acuacgccuc cgaggccauc aagggcgccg      240

ucgucggcau cgaccucggc accaccaacu ccugcgucgc cgucauggag ggcaagcagg      300

ccaagguccu cgagaacgcc gagggcgccc gcaccacccc cuccgucguc gccuucaccg      360

ccgacggcga gcgccucguc ggcaugcccg ccaagcgcca ggccgucacc aaccccaaca      420

acaccuucua cgccaccaag cgccucaucg gccgccgcua cgacgacccc gagguccaga      480

aggacaucaa gaacgucccc uucaagaucg uccgcgccuc caacggcgac gccugggucg      540

aggcccacgg caagcucuac ucccccuccc agaucggcgc cuucguccuc augaagauga      600

aggagaccgc cgagaacuac cucggccaca ccgccaagaa cgccgucauc accguccccg      660

ccuacuucaa cgacucccag cgccaggcca ccaaggacgc cggccagauc uccggccuca      720

acguccuccg cgucaucaac gagcccaccg ccgccgcccu cgccuacggc cucgacaagu      780

ccgaggacaa ggucaucgcc gucuacgacc ucggcggcgg caccuucgac aucuccaucc      840

ucgagaucca gaagggcguc uucgagguca aguccaccaa cggcgacacc uuccucggcg      900

gcgaggacuu cgaccaggcc cuccuccgcc acaucgucaa ggaguucaag cgcgagaccg      960

gcgucgaccu caccaaggac aacauggccc uccagcgcgu ccgcgaggcc gccgagaagg     1020

ccaagugcga gcucuccucc uccguccaga ccgacaucaa ccuccccuac cucaccaugg     1080

acuccuccgg ccccaagcac cucaacauga agcucacccg cgcccaguuc gagggcaucg     1140

ucaccgaccu cauccgccgc accaucgccc ccugccagaa ggccaugcag gacgccgagg     1200

ucuccaaguc cgacaucggc gaggucaucc ucgucggcgg caugacccgc augcccaagg     1260

uccagcagac cguccaggac cucuucggcc gcgcccccuc caaggccguc aaccccgacg     1320

aggccgucgc caucggcgcc gccauccagg gcggcguccu cgccggcgac gucaccgacg     1380

uccuccuccu cgacgucacc ccccucuccc ucggcaucga gacccucggc ggcgucuuca     1440

ccaagcucau caaccgcaac accaccaucc ccaccaagaa gucccagguc uucuccaccg     1500

ccgccgacgg ccagacccag gucgagauca aggucugcca gggcgagcgc gagauggccg     1560

gcgacaacaa gcuccucggc caguucaccc ucaucggcau cccccccgcc ccccgcggcg     1620

ucccccagau cgaggucacc uucgacaucg acgccaacgg caucguccac gucuccgcca     1680

aggacaaggg caccggccgc gagcagcaga ucgucaucca guccuccggc ggccucucca     1740

aggacgacau cgagaacaug gucaagaacg ccgagaagua cgccgaggag gaccgccgca     1800

agaaggagcg cgucgaggcc gucaacaugg ccgagggcau cauccacgac accgagacca     1860

agauggagga guucaaggac cagcuccccg ccgacgagug caacaagcuc aaggaggaga     1920

ucuccaagau gcgcgagcuc cucgcccgca aggacuccga gaccggcgag aacauccgcc     1980

aggccgccuc cucccuccag caggccuccc ucaagcucuu cgagauggcc uacaagaaga     2040

uggccuccga gcgcgagggc uccggcuccu ccggcaccgg cgagcagaag gaggaccaga     2100

aggaggagaa gcagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  4051
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt2)

<400>  4051
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg aggccggcgg cuccgacggc ccccgcgaga      120

ccgcccccac cuccgccuac uccucccccg cccgcucccu cggcgacacc ggcaucaccc      180

cccucucccc cucccacauc gucaacgaca ccgacuccaa cgucuccgag cagcaguccu      240

uccucgucgu cgucgccguc gacuucggca ccaccuccuc cggcuacgcc uacuccuuca      300

ccaaggagcc cgagugcauc cacgucaugc gccgcuggga gggcggcgac cccggcgucu      360

ccaaccagaa gacccccacc accauccucc ucacccccga gcgcaaguuc cacuccuucg      420

gcuacgccgc ccgcgacuuc uaccacgacc ucgaccccaa cgaggccaag caguggcucu      480

accucgagaa guucaagaug aagcuccaca ccaccggcga ccucaccaug gacaccgacc      540

ucaccgccgc caacggcaag aaggucaagg cccucgagau cuucgccuac gcccuccagu      600

acuucaagga gcaggcccuc aaggagcucu ccgaccaggc cggcuccgag uucgagaacu      660

ccgacguccg cugggucauc accguccccg ccaucuggaa gcagcccgcc aagcaguuca      720

ugcgccaggc cgccuaccag gccggccucg ccucccccga gaacuccgag cagcucauca      780

ucgcccucga gcccgaggcc gccuccaucu acugccgcaa gcuccgccuc caccagauga      840

ucgagcucuc cuccaaggcc gccgucaacg gcuacuccgg cuccgacacc gucggcgccg      900

gcuucaccca ggccaaggag cacauccgcc gcaaccgcca gucccgcacc uuccucgucg      960

agaacgucau cggcgagauc ugguccgagc ucgaggaggg cgacaaguac gucgucgucg     1020

acuccggcgg cggcaccguc gaccucaccg uccaccagau ccgccucccc gagggccacc     1080

ucaaggagcu cuacaaggcc accggcggcc ccuacggcuc ccucggcguc gacuacgagu     1140

ucgagaagcu ccucuacaag aucuucggcg aggacuucau cgagcaguuc aagaucaagc     1200

gccccgccgc cugggucgac cucaugaucg ccuucgaguc ccgcaagcgc gccgccgccc     1260

ccgaccgcac caacccccuc aacaucaccc uccccuucuc cuucaucgac uacuacaaga     1320

aguuccgcgg ccacuccguc gagcacgccc uccgcaaguc caacgucgac uucgucaagu     1380

gguccuccca gggcaugcuc cgcauguccc ccgacgccau gaacgcccuc uucaagccca     1440

ccaucgacuc caucaucgag caccuccgcg accucuucca gaagcccgag gucuccaccg     1500

ucaaguuccu cuuccucguc ggcggcuucg ccgaggcccc ccuccuccag caggccgucc     1560

aggccgccuu cggcgaccag ugccgcauca ucauccccca ggacgucggc cucaccaucc     1620

ucaagggcgc cguccucuuc ggccucgacc ccgccgucau caagguccgc cgcucccccc     1680

ucaccuacgg cgucggcguc cucaaccgcu acgucgaggg caagcacccc cccgagaagc     1740

uccucgucaa ggacggcacc cgcuggugca ccgacgucuu cgacaaguuc aucuccgccg     1800

accaguccgu cgcccucggc gagcucguca agcgcuccua cacccccgcc aagcccuccc     1860

agcucgucau cgucaucaac aucuacuccu ccgagcacga caacgucucc uucaucaccg     1920

accccggcgu caagaagugc ggcacccucc gccucgaccu caccggcacc uccggcaccg     1980

ccguccccgc ccgccgcgag auccagaccc ucaugcaguu cggcgacacc gagaucaagg     2040

ccaccgccau cgacaucgcc accuccaagu ccgucaaggu cggcaucgac uuccucaacu     2100

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  4052
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt2)

<400>  4052
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cucgccgucc ccgagauggg ccuccagggc cucuacaucg      120

gcuccucccc cgagcgcucc cccguccccu ccccccccgg cuccccccgc acccaggagu      180

ccugcggcau cgccccccuc acccccuccc agucccccaa gcccgagguc cgcgcccccc      240

agcaggccuc cuucuccguc gucgucgcca ucgacuucgg caccaccucc uccggcuacg      300

ccuucuccuu cgccuccgac cccgaggcca uccacaugau gcgcaagugg gagggcggcg      360

accccggcgu cgcccaccag aagaccccca ccugccuccu ccucaccccc gagggcgccu      420

uccacuccuu cggcuacacc gcccgcgacu acuaccacga ccucgacccc gaggaggccc      480

gcgacuggcu cuacuucgag aaguucaaga ugaagaucca cuccgccacc gaccucaccc      540

ucaagaccca gcucgaggcc gucaacggca agaccaugcc cgcccucgag gucuucgccc      600

acgcccuccg cuucuuccgc gagcacgccc uccaggagcu ccgcgagcag ucccccuccc      660

uccccgagaa ggacaccguc cgcugggucc ucaccguccc cgccaucugg aagcagcccg      720

ccaagcaguu caugcgcgag gccgccuacc ucgccggccu cgucucccgc gagaacgccg      780

agcagcuccu caucgcccuc gagcccgagg ccgccuccgu cuacugccgc aagcuccgcc      840

uccaccagcu ccucgaccuc uccggccgcg cccccggcgg cggccgccuc ggcgagcgcc      900

gcuccaucga cuccuccuuc cgccaggccc gcgagcagcu ccgccgcucc cgccacuccc      960

gcaccuuccu cgucgagucc ggcgucggcg agcucugggc cgagaugcag gccggcgacc     1020

gcuacgucgu cgccgacugc ggcggcggca ccgucgaccu caccguccac cagcucgagc     1080

agccccacgg cacccucaag gagcucuaca aggccuccgg cggccccuac ggcgccgucg     1140

gcgucgaccu cgccuucgag cagcuccucu gccgcaucuu cggcgaggac uucaucgcca     1200

ccuucaagcg ccagcgcccc gccgccuggg ucgaccucac caucgccuuc gaggcccgca     1260

agcgcaccgc cggcccccac cgcgccggcg cccucaacau cucccucccc uucuccuuca     1320

ucgacuucua ccgcaagcag cgcggccaca acgucgagac cgcccuccgc cgcuccuccg     1380

ucaacuucgu caaguggucc ucccagggca ugcuccgcau guccugcgag gccaugaacg     1440

agcucuucca gcccaccguc uccggcauca uccagcacau cgaggcccuc cucgcccgcc     1500

ccgaggucca gggcgucaag cuccucuucc ucgucggcgg cuucgccgag uccgccgucc     1560

uccagcacgc cguccaggcc gcccucggcg cccgcggccu ccgcgucguc gucccccacg     1620

acgucggccu caccauccuc aagggcgccg uccucuucgg ccaggccccc ggcgucgucc     1680

gcguccgccg cuccccccuc accuacggcg ucggcguccu caaccgcuuc guccccggcc     1740

gccacccccc cgagaagcuc cucguccgcg acggccgccg cuggugcacc gacgucuucg     1800

agcgcuucgu cgccgccgag caguccgucg cccucggcga ggagguccgc cgcuccuacu     1860

gccccgcccg ccccggccag cgccgcgucc ucaucaaccu cuacugcugc gccgccgagg     1920

acgcccgcuu caucaccgac cccggcgucc gcaagugcgg cgcccucucc cucgagcucg     1980

agcccgccga cugcggccag gacaccgccg gcgccccccc cggccgccgc gagauccgcg     2040

ccgccaugca guucggcgac accgagauca aggucaccgc cgucgacguc uccaccaacc     2100

gcuccguccg cgccuccauc gacuuccucu ccaacugagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  4053
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt2)

<400>  4053
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgcgaga ugaccauccu cggcuccgcc guccucaccc      120

uccuccucgc cggcuaccuc gcccagcagu accucccccu ccccaccccc aaggucaucg      180

gcaucgaccu cggcaccacc uacugcuccg ucggcgucuu cuuccccggc accggcaagg      240

ucaaggucau ccccgacgag aacggccaca ucuccauccc cuccaugguc uccuucaccg      300

acaacgacgu cuacgucggc uacgaguccg ucgagcucgc cgacuccaac ccccagaaca      360

ccaucuacga cgccaagcgc uucaucggca agaucuucac cgccgaggag cucgaggccg      420

agaucggccg cuaccccuuc aagguccuca acaagaacgg cauggucgag uucuccguca      480

ccuccaacga gaccaucacc gucucccccg aguacgucgg cucccgccuc cuccucaagc      540

ucaaggagau ggccgaggcc uaccucggca ugcccgucgc caacgccguc aucuccgucc      600

ccgccgaguu cgaccucaag cagcgcaacu ccaccaucga ggccgccaac cucgccggcc      660

ucaagauccu ccgcgucauc aacgagccca ccgccgccgc cauggccuac ggccuccaca      720

aggccgacgu cuuccacguc cucgucaucg accucggcgg cggcacccuc gacgucuccc      780

uccucaacaa gcagggcggc auguuccuca cccgcgccau guccggcaac aacaagcucg      840

gcggccagga cuucaaccag cgccuccucc aguaccucua caagcagauc uaccagaccu      900

acggcuucgu ccccucccgc aaggaggaga uccaccgccu ccgccaggcc gucgagaugg      960

ucaagcucaa ccucacccuc caccaguccg cccagcucuc cguccuccuc accgucgagg     1020

agcaggaccg caaggagccc cacuccuccg acaccgagcu ccccaaggac aagcucuccu     1080

ccgccgacga ccaccgcguc aacuccggcu ucggccgcgg ccucuccgac aagaaguccg     1140

gcgaguccca gguccucuuc gagaccgaga ucucccgcaa gcucuucgac acccucaacg     1200

aggaccucuu ccagaagauc cucgucccca uccagcaggu ccucaaggag ggccaccucg     1260

agaagaccga gaucgacgag gucguccucg ucggcggcuc cacccgcauc ccccgcaucc     1320

gccaggucau ccaggaguuc uucggcaagg accccaacac cuccgucgac cccgaccucg     1380

ccgucgucac cggcgucgcc auccaggccg gcaucgacgg cggcuccugg ccccuccagg     1440

ucuccgcccu cgagaucccc aacaagcacc uccagaagac caacuucaac ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4054
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt2)

<400>  4054
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgccaucg gcguccaccu cggcugcacc uccgccugcg      120

ucgccgucua caaggacggc cgcgccggcg ucgucgccaa cgacgccggc gaccgcguca      180

cccccgccgu cgucgccuac uccgagaacg aggagaucgu cggccucgcc gccaagcagu      240

cccgcauccg caacaucucc aacaccguca ugaaggucaa gcagauccuc ggccgcuccu      300

ccuccgaccc ccaggcccag aaguacaucg ccgaguccaa gugccucguc aucgagaaga      360

acggcaagcu ccgcuacgag aucgacaccg gcgaggagac caaguucguc aaccccgagg      420

acgucgcccg ccucaucuuc uccaagauga aggagaccgc ccacuccguc cucggcuccg      480

acgccaacga cgucgucauc accguccccu ucgacuucgg cgagaagcag aagaacgccc      540

ucggcgaggc cgcccgcgcc gccggcuuca acguccuccg ccucauccac gagcccuccg      600

ccgcccuccu cgccuacggc aucggccagg acucccccac cggcaagucc aacauccucg      660

ucuucaagcu cggcggcacc ucccucuccc ucuccgucau ggaggucaac uccggcaucu      720

accgcguccu cuccaccaac accgacgaca acaucggcgg cgcccacuuc accgagaccc      780

ucgcccagua ccucgccucc gaguuccagc gcuccuucaa gcacgacguc cgcggcaacg      840

cccgcgccau gaugaagcuc accaacuccg ccgaggucgc caagcacucc cucuccaccc      900

ucggcuccgc caacugcuuc cucgacuccc ucuacgaggg ccaggacuuc gacugcaacg      960

ucucccgcgc ccgcuucgag cuccucugcu ccccccucuu caacaagugc aucgaggcca     1020

uccgcggccu ccucgaccag aacggcuuca ccgccgacga caucaacaag gucguccucu     1080

gcggcggcuc cucccgcauc cccaagcucc agcagcucau caaggaccuc uuccccgccg     1140

ucgagcuccu caacuccauc ccccccgacg aggucauccc caucggcgcc gccaucgagg     1200

ccggcauccu caucggcaag gagaaccucc ucgucgagga cucccucaug aucgagugcu     1260

ccgcccgcga cauccucguc aagggcgucg acgaguccgg cgccucccgc uucaccgucc     1320

ucuuccccuc cggcaccccc cuccccgccc gccgccagca cacccuccag gcccccggcu     1380

ccaucuccuc cgucugccuc gagcucuacg aguccgacgg caagaacucc gccaaggagg     1440

agaccaaguu cgcccagguc guccuccagg accucgacaa gaaggagaac ggccuccgcg     1500

acauccucgc cguccucacc augaagcgcg acggcucccu ccacgucacc ugcaccgacc     1560

aggagaccgg caagugcgag gccaucucca ucgagaucgc cuccugagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  4055
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt2)

<400>  4055
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgucgucg gccucgacgu cggcucccag uccugcuaca      120

ucgccgucgc ccgcgccggc ggcaucgaga ccaucgccaa cgaguucucc gaccgcugca      180

cccccuccgu caucuccuuc ggcuccaaga accgcaccau cggcgucgcc gccaagaacc      240

agcagaucac ccacgccaac aacaccgucu ccaacuucaa gcgcuuccac ggccgcgccu      300

ucaacgaccc cuucauccag aaggagaagg agaaccucuc cuacgaccuc gucccccuca      360

agaacggcgg cgucggcauc aaggucaugu acaugggcga ggagcaccuc uucuccgucg      420

agcagaucac cgccaugcuc cucaccaagc ucaaggagac cgccgagaac ucccucaaga      480

agcccgucac cgacugcguc aucuccgucc ccuccuucuu caccgacgcc gagcgccgcu      540

ccguccucga cgccgcccag aucgucggcc ucaacugccu ccgccucaug aacgacauga      600

ccgccgucgc ccucaacuac ggcaucuaca agcaggaccu ccccucccuc gacgagaagc      660

cccgcaucgu cgucuucguc gacaugggcc acuccgccuu ccaggucucc gccugcgccu      720

ucaacaaggg caagcucaag guccucggca ccgccuucga ccccuuccuc ggcggcaaga      780

acuucgacga gaagcucguc gagcacuucu gcgccgaguu caagaccaag uacaagcucg      840

acgccaaguc caagauccgc gcccuccucc gccucuacca ggagugcgag aagcucaaga      900

agcucauguc cuccaacucc accgaccucc cccucaacau cgagugcuuc augaacgaca      960

aggacgucuc cggcaagaug aaccgcuccc aguucgagga gcucugcgcc gagcuccucc     1020

agaagaucga ggucccccuc uacucccucc ucgagcagac ccaccucaag gucgaggacg     1080

ucuccgccgu cgagaucguc ggcggcgcca cccgcauccc cgccgucaag gagcgcaucg     1140

ccaaguucuu cggcaaggac aucuccacca cccucaacgc cgacgaggcc gucgcccgcg     1200

gcugcgcccu ccagugcgcc auccucuccc ccgccuucaa gguccgcgag uucuccguca     1260

ccgacgccgu ccccuucccc aucucccuca ucuggaacca cgacuccgag gacaccgagg     1320

gcguccacga ggucuucucc cgcaaccacg ccgcccccuu cuccaagguc cucaccuucc     1380

uccgccgcgg ccccuucgag cucgaggccu ucuacuccga cccccagggc guccccuacc     1440

ccgaggccaa gaucggccgc uucgucgucc agaacgucuc cgcccagaag gacggcgaga     1500

agucccgcgu caaggucaag guccgcguca acacccacgg caucuucacc aucuccaccg     1560

ccuccauggu cgagaagguc cccaccgagg agaacgagau guccuccgag gccgacaugg     1620

agugccucaa ccagcgcccc cccgagaacc ccgacaccga caagaacguc cagcaggaca     1680

acuccgaggc cggcacccag ccccaggucc agaccgacgc ccagcagacc ucccaguccc     1740

cccccucccc cgagcucacc uccgaggaga acaagauccc cgacgccgac aaggccaacg     1800

agaagaaggu cgaccagccc cccgaggcca agaagcccaa gaucaagguc gucaacgucg     1860

agcuccccau cgaggccaac cucgucuggc agcucggcaa ggaccuccuc aacauguaca     1920

ucgagaccga gggcaagaug aucaugcagg acaagcucga gaaggagcgc aacgacgcca     1980

agaacgccgu cgaggaguac gucuacgagu uccgcgacaa gcucugcggc cccuacgaga     2040

aguucaucug cgagcaggac caccagaacu uccuccgccu ccucaccgag accgaggacu     2100

ggcucuacga ggagggcgag gaccaggcca agcaggccua cgucgacaag cucgaggagc     2160

ucaugaagau cggcaccccc gucaaggucc gcuuccagga ggccgaggag cgccccaaga     2220

uguucgagga gcucggccag cgccuccagc acuacgccaa gaucgccgcc gacuuccgca     2280

acaaggacga gaaguacaac cacaucgacg aguccgagau gaagaagguc gagaaguccg     2340

ucaacgaggu cauggagugg augaacaacg ucaugaacgc ccaggccaag aagucccucg     2400

accaggaccc cgucguccgc gcccaggaga ucaagaccaa gaucaaggag cucaacaaca     2460

ccugcgagcc cgucgucacc cagcccaagc ccaagaucga gucccccaag cucgagcgca     2520

cccccaacgg ccccaacauc gacaagaagg aggaggaccu cgaggacaag aacaacuucg     2580

gcgccgagcc cccccaccag aacggcgagu gcuaccccaa cgagaagaac uccgucaaca     2640

uggaccucga cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  4056
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt2)

<400>  4056
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg uccgccgcca gcgcccccgc cgccgcgucu      120

gcugggcccu cgucgccguc cuccucgccg accuccucgc ccucuccgac acccucgccg      180

ucauguccgu cgaccucggc uccgagucca ugaaggucgc caucgucaag cccggcgucc      240

ccauggagau cguccucaac aaggaguccc gccgcaagac ccccgucauc gucacccuca      300

aggagaacga gcgcuucuuc ggcgacuccg ccgccuccau ggccaucaag aaccccaagg      360

ccacccuccg cuacuuccag caccuccucg gcaagcaggc cgacaacccc cacgucgccc      420

ucuaccaggc ccgcuucccc gagcacgagc ucaccuucga cccccagcgc cagaccgucc      480

acuuccagau cuccucccag cuccaguucu cccccgagga gguccucggc augguccuca      540

acuacucccg cucccucgcc gaggacuucg ccgagcagcc caucaaggac gccgucauca      600

ccguccccgu cuucuucaac caggccgagc gccgcgccgu ccuccaggcc gcccgcaugg      660

ccggccucaa gguccuccag cucaucaacg acaacaccgc caccgcccuc uccuacggcg      720

ucuuccgccg caaggacauc aacaccaccg cccagaacau cauguucuac gacaugggcu      780

ccggcuccac cgucugcacc aucgucaccu accagauggu caagaccaag gaggccggca      840

ugcagcccca gcuccagauc cgcggcgucg gcuucgaccg cacccucggc ggccucgaga      900

uggagcuccg ccuccgcgag cgccucgccg gccucuucaa cgagcagcgc aagggccagc      960

gcgccaagga cguccgcgag aacccccgcg ccauggccaa gcuccuccgc gaggccaacc     1020

gccucaagac cguccucucc gccaacgccg accacauggc ccagaucgag ggccucaugg     1080

acgacgucga cuucaaggcc aaggucaccc gcgucgaguu cgaggagcuc ugcgccgacc     1140

ucuucgagcg cguccccggc cccguccagc aggcccucca guccgccgag augucccucg     1200

acgagaucga gcaggucauc cucgucggcg gcgccacccg cgucccccgc guccaggagg     1260

uccuccucaa ggccgucggc aaggaggagc ucggcaagaa caucaacgcc gacgaggccg     1320

ccgccauggg cgccgucuac caggccgccg cccucuccaa ggccuucaag gucaagcccu     1380

ucgucguccg cgacgccguc gucuacccca uccucgucga guucacccgc gaggucgagg     1440

aggagcccgg cauccacucc cucaagcaca acaagcgcgu ccucuucucc cgcaugggcc     1500

ccuaccccca gcgcaagguc aucaccuuca accgcuacuc ccacgacuuc aacuuccaca     1560

ucaacuacgg cgaccucggc uuccucggcc ccgaggaccu ccgcgucuuc ggcucccaga     1620

accucaccac cgucaagcuc aagggcgucg gcgacuccuu caagaaguac cccgacuacg     1680

aguccaaggg caucaaggcc cacuucaacc ucgacgaguc cggcguccuc ucccucgacc     1740

gcgucgaguc cgucuucgag acccucgucg aggacuccgc cgaggaggag uccacccuca     1800

ccaagcucgg caacaccauc uccucccucu ucggcggcgg caccaccccc gacgccaagg     1860

agaacggcac cgacaccguc caggaggagg aggagucccc cgccgagggc uccaaggacg     1920

agcccggcga gcaggucgag cucaaggagg aggccgaggc ccccgucgag gacggcuccc     1980

agcccccccc ccccgagccc aagggcgacg ccacccccga gggcgagaag gccaccgaga     2040

aggagaacgg cgacaagucc gaggcccaga agcccuccga gaaggccgag gccggccccg     2100

agggcgucgc ccccgccccc gagggcgaga agaagcagaa gcccgcccgc aagcgccgca     2160

uggucgagga gaucggcguc gagcucgucg uccucgaccu ccccgaccuc cccgaggaca     2220

agcucgccca guccguccag aagcuccagg accucacccu ccgcgaccuc gagaagcagg     2280

agcgcgagaa ggccgccaac ucccucgagg ccuucaucuu cgagacccag gacaagcucu     2340

accagcccga guaccaggag gucuccaccg aggagcagcg cgaggagauc uccggcaagc     2400

ucuccgccgc cuccaccugg cucgaggacg agggcgucgg cgccaccacc gucaugcuca     2460

aggagaagcu cgccgagcuc cgcaagcucu gccagggccu cuucuuccgc gucgaggagc     2520

gcaagaagug gcccgagcgc cucuccgccc ucgacaaccu ccucaaccac uccuccaugu     2580

uccucaaggg cgcccgccuc auccccgaga uggaccagau cuucaccgag gucgagauga     2640

ccacccucga gaaggucauc aacgagaccu gggccuggaa gaacgccacc cucgccgagc     2700

aggccaagcu ccccgccacc gagaagcccg uccuccucuc caaggacauc gaggccaaga     2760

ugauggcccu cgaccgcgag guccaguacc uccucaacaa ggccaaguuc accaagcccc     2820

gcccccgccc caaggacaag aacggcaccc gcgccgagcc cccccucaac gccuccgccu     2880

ccgaccaggg cgagaagguc aucccccccg ccggccagac cgaggacgcc gagcccaucu     2940

ccgagcccga gaaggucgag accggcuccg agcccggcga caccgagccc cucgagcucg     3000

gcggccccgg cgccgagccc gagcagaagg agcaguccac cggccagaag cgcccccuca     3060

agaacgacga gcucugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4057
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt2)

<400>  4057
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaga cccagaccca ggaccagccc auggaggagg      120

aggaggucga gaccuucgcc uuccaggccg agaucgccca gcucaugucc cucaucauca      180

acaccuucua cuccaacaag gagaucuucc uccgcgagcu caucuccaac uccuccgacg      240

cccucgacaa gauccgcuac gagucccuca ccgaccccuc caagcucgac uccggcaagg      300

agcuccacau caaccucauc cccaacaagc aggaccgcac ccucaccauc gucgacaccg      360

gcaucggcau gaccaaggcc gaccucauca acaaccucgg caccaucgcc aaguccggca      420

ccaaggccuu cauggaggcc cuccaggccg gcgccgacau cuccaugauc ggccaguucg      480

gcgucggcuu cuacuccgcc uaccucgucg ccgagaaggu caccgucauc accaagcaca      540

acgacgacga gcaguacgcc ugggaguccu ccgccggcgg cuccuucacc guccgcaccg      600

acaccggcga gcccaugggc cgcggcacca aggucauccu ccaccucaag gaggaccaga      660

ccgaguaccu cgaggagcgc cgcaucaagg agaucgucaa gaagcacucc caguucaucg      720

gcuaccccau cacccucuuc gucgagaagg agcgcgacaa ggaggucucc gacgacgagg      780

ccgaggagaa ggaggacaag gaggaggaga aggagaagga ggagaaggag uccgaggaca      840

agcccgagau cgaggacguc ggcuccgacg aggaggagga gaagaaggac ggcgacaaga      900

agaagaagaa gaagaucaag gagaaguaca ucgaccagga ggagcucaac aagaccaagc      960

ccaucuggac ccgcaacccc gacgacauca ccaacgagga guacggcgag uucuacaagu     1020

cccucaccaa cgacugggag gaccaccucg ccgucaagca cuucuccguc gagggccagc     1080

ucgaguuccg cgcccuccuc uucguccccc gccgcgcccc cuucgaccuc uucgagaacc     1140

gcaagaagaa gaacaacauc aagcucuacg uccgccgcgu cuucaucaug gacaacugcg     1200

aggagcucau ccccgaguac cucaacuuca uccgcggcgu cgucgacucc gaggaccucc     1260

cccucaacau cucccgcgag augcuccagc aguccaagau ccucaagguc auccgcaaga     1320

accucgucaa gaagugccuc gagcucuuca ccgagcucgc cgaggacaag gagaacuaca     1380

agaaguucua cgagcaguuc uccaagaaca ucaagcucgg cauccacgag gacucccaga     1440

accgcaagaa gcucuccgag cuccuccgcu acuacaccuc cgccuccggc gacgagaugg     1500

ucucccucaa ggacuacugc acccgcauga aggagaacca gaagcacauc uacuacauca     1560

ccggcgagac caaggaccag gucgccaacu ccgccuucgu cgagcgccuc cgcaagcacg     1620

gccucgaggu caucuacaug aucgagccca ucgacgagua cugcguccag cagcucaagg     1680

aguucgaggg caagacccuc gucuccguca ccaaggaggg ccucgagcuc cccgaggacg     1740

aggaggagaa gaagaagcag gaggagaaga agaccaaguu cgagaaccuc ugcaagauca     1800

ugaaggacau ccucgagaag aaggucgaga aggucgucgu cuccaaccgc cucgucaccu     1860

cccccugcug caucgucacc uccaccuacg gcuggaccgc caacauggag cgcaucauga     1920

aggcccaggc ccuccgcgac aacuccacca ugggcuacau ggccgccaag aagcaccucg     1980

agaucaaccc cgaccacucc aucaucgaga cccuccgcca gaaggccgag gccgacaaga     2040

acgacaaguc cgucaaggac cucgucaucc uccucuacga gaccgcccuc cucuccuccg     2100

gcuucucccu cgaggacccc cagacccacg ccaaccgcau cuaccgcaug aucaagcucg     2160

gccucggcau cgacgaggac gaccccaccg ccgacgacac cuccgccgcc gucaccgagg     2220

agaugccccc ccucgagggc gacgacgaca ccucccgcau ggaggagguc gacugaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  4058
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt2)

<400>  4058
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccucca agcucgacuc cggcaagggc cuccacauca      120

accucguccc caacaagcag aaccagaccc ucaccaucgu cgacacccgc aucggcauga      180

ccaagaccga ccucaucaac aaccucggca ccgucaccaa guccggcacc aaggccuuca      240

uggaggcccu ccaggccgac gccgacaucu ccaugaucgg ccacuucggc gucggcuucu      300

acuccgccua ccucgucgcc aagaagguca ccgucaucuc caagcacaac aacgacgagc      360

aguacaccug ggaguccucc gccggcggcu ccuucaccgu ccgcaccgac gagugaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  4059
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt2)

<400>  4059
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggagg uccaccacgg cgaggaggag gucgagaccu      120

ucgccuucca ggccgagauc gcccagcuca ugucccucau caucaacacc uucuacucca      180

acaaggagau cuuccuccgc gagcucaucu ccaacgccuc cgacgcccuc gacaagaucc      240

gcuacgaguc ccucaccgac cccuccaagc ucgacuccgg caaggagcuc aagaucgaca      300

ucauccccaa cccccaggag cgcacccuca cccucgucga caccggcauc ggcaugacca      360

aggccgaccu caucaacaac cucggcacca ucgccaaguc cggcaccaag gccuucaugg      420

aggcccucca ggccggcgcc gacaucucca ugaucggcca guucggcguc ggcuucuacu      480

ccgccuaccu cgucgccgag aaggucgucg ucaucaccaa gcacaacgac gacgagcagu      540

acgccuggga guccuccgcc ggcggcuccu ucaccguccg cgccgaccac ggcgagccca      600

ucggccgcgg caccaagguc auccuccacc ucaaggagga ccagaccgag uaccucgagg      660

agcgccgcgu caaggagguc gucaagaagc acucccaguu caucggcuac cccaucaccc      720

ucuaccucga gaaggagcgc gagaaggaga ucuccgacga cgaggccgag gaggagaagg      780

gcgagaagga ggaggaggac aaggacgacg aggagaagcc caagaucgag gacgucggcu      840

ccgacgagga ggacgacucc ggcaaggaca agaagaagaa gaccaagaag aucaaggaga      900

aguacaucga ccaggaggag cucaacaaga ccaagcccau cuggacccgc aaccccgacg      960

acaucaccca ggaggaguac ggcgaguucu acaagucccu caccaacgac ugggaggacc     1020

accucgccgu caagcacuuc uccgucgagg gccagcucga guuccgcgcc cuccucuuca     1080

ucccccgccg cgcccccuuc gaccucuucg agaacaagaa gaagaagaac aacaucaagc     1140

ucuacguccg ccgcgucuuc aucauggacu ccugcgacga gcucaucccc gaguaccuca     1200

acuucauccg cggcgucguc gacuccgagg accucccccu caacaucucc cgcgagaugc     1260

uccagcaguc caagauccuc aaggucaucc gcaagaacau cgucaagaag ugccucgagc     1320

ucuucuccga gcucgccgag gacaaggaga acuacaagaa guucuacgag gccuucucca     1380

agaaccucaa gcucggcauc cacgaggacu ccaccaaccg ccgccgccuc uccgagcucc     1440

uccgcuacca caccucccag uccggcgacg agaugaccuc ccucuccgag uacgucuccc     1500

gcaugaagga gacccagaag uccaucuacu acaucaccgg cgaguccaag gagcaggucg     1560

ccaacuccgc cuucgucgag cgcguccgca agcgcggcuu cgaggucguc uacaugaccg     1620

agcccaucga cgaguacugc guccagcagc ucaaggaguu cgacggcaag ucccucgucu     1680

ccgucaccaa ggagggccuc gagcuccccg aggacgagga ggagaagaag aagauggagg     1740

aguccaaggc caaguucgag aaccucugca agcucaugaa ggagauccuc gacaagaagg     1800

ucgagaaggu caccaucucc aaccgccucg ucuccucccc cugcugcauc gucaccucca     1860

ccuacggcug gaccgccaac auggagcgca ucaugaaggc ccaggcccuc cgcgacaacu     1920

ccaccauggg cuacaugaug gccaagaagc accucgagau caaccccgac caccccaucg     1980

ucgagacccu ccgccagaag gccgaggccg acaagaacga caaggccguc aaggaccucg     2040

ucguccuccu cuucgagacc gcccuccucu ccuccggcuu cucccucgag gacccccaga     2100

cccacuccaa ccgcaucuac cgcaugauca agcucggccu cggcaucgac gaggacgagg     2160

ucgccgccga ggagcccaac gccgccgucc ccgacgagau ccccccccuc gagggcgacg     2220

aggacgccuc ccgcauggag gaggucgacu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  4060
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt2)

<400>  4060
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcgcccucu ggguccucgg ccucugcugc guccuccuca      120

ccuucggcuc cguccgcgcc gacgacgagg ucgacgucga cggcaccguc gaggaggacc      180

ucggcaaguc ccgcgagggc ucccgcaccg acgacgaggu cguccagcgc gaggaggagg      240

ccauccagcu cgacggccuc aacgccuccc agauccgcga gcuccgcgag aaguccgaga      300

aguucgccuu ccaggccgag gucaaccgca ugaugaagcu caucaucaac ucccucuaca      360

agaacaagga gaucuuccuc cgcgagcuca ucuccaacgc cuccgacgcc cucgacaaga      420

uccgccucau cucccucacc gacgagaacg cccucuccgg caacgaggag cucaccguca      480

agaucaagug cgacaaggag aagaaccucc uccacgucac cgacaccggc gucggcauga      540

cccgcgagga gcucgucaag aaccucggca ccaucgccaa guccggcacc uccgaguucc      600

ucaacaagau gaccgaggcc caggaggacg gccaguccac cuccgagcuc aucggccagu      660

ucggcgucgg cuucuacucc gccuuccucg ucgccgacaa ggucaucguc accuccaagc      720

acaacaacga cacccagcac aucugggagu ccgacuccaa cgaguucucc gucaucgccg      780

acccccgcgg caacacccuc ggccgcggca ccaccaucac ccucguccuc aaggaggagg      840

ccuccgacua ccucgagcuc gacaccauca agaaccucgu caagaaguac ucccaguuca      900

ucaacuuccc caucuacguc ugguccucca agaccgagac cgucgaggag cccauggagg      960

aggaggaggc cgccaaggag gagaaggagg aguccgacga cgaggccgcc gucgaggagg     1020

aggaggagga gaagaagccc aagaccaaga aggucgagaa gaccgucugg gacugggagc     1080

ucaugaacga caucaagccc aucuggcagc gccccuccaa ggaggucgag gaggacgagu     1140

acaaggccuu cuacaagucc uucuccaagg aguccgacga ccccauggcc uacauccacu     1200

ucaccgccga gggcgagguc accuucaagu ccauccucuu cguccccacc uccgcccccc     1260

gcggccucuu cgacgaguac ggcuccaaga aguccgacua caucaagcuc uacguccgcc     1320

gcgucuucau caccgacgac uuccacgaca ugaugcccaa guaccucaac uucgucaagg     1380

gcgucgucga cuccgacgac cucccccuca acgucucccg cgagacccuc cagcagcaca     1440

agcuccucaa ggucauccgc aagaagcucg uccgcaagac ccucgacaug aucaagaaga     1500

ucgccgacga caaguacaac gacaccuucu ggaaggaguu cggcaccaac aucaagcucg     1560

gcgucaucga ggaccacucc aaccgcaccc gccucgccaa gcuccuccgc uuccaguccu     1620

cccaccaccc caccgacauc accucccucg accaguacgu cgagcgcaug aaggagaagc     1680

aggacaagau cuacuucaug gccggcuccu cccgcaagga ggccgagucc ucccccuucg     1740

ucgagcgccu ccucaagaag ggcuacgagg ucaucuaccu caccgagccc gucgacgagu     1800

acugcaucca ggcccucccc gaguucgacg gcaagcgcuu ccagaacguc gccaaggagg     1860

gcgucaaguu cgacgagucc gagaagacca aggagucccg cgaggccguc gagaaggagu     1920

ucgagccccu ccucaacugg augaaggaca aggcccucaa ggacaagauc gagaaggccg     1980

ucgucuccca gcgccucacc gagucccccu gcgcccucgu cgccucccag uacggcuggu     2040

ccggcaacau ggagcgcauc augaaggccc aggccuacca gaccggcaag gacaucucca     2100

ccaacuacua cgccucccag aagaagaccu ucgagaucaa cccccgccac ccccucaucc     2160

gcgacaugcu ccgccgcauc aaggaggacg aggacgacaa gaccguccuc gaccucgccg     2220

ucguccucuu cgagaccgcc acccuccgcu ccggcuaccu ccuccccgac accaaggccu     2280

acggcgaccg caucgagcgc augcuccgcc ucucccucaa caucgacccc gacgccaagg     2340

ucgaggagga gcccgaggag gagcccgagg agaccgccga ggacaccacc gaggacaccg     2400

agcaggacga ggacgaggag auggacgucg gcaccgacga ggaggaggag accgccaagg     2460

aguccaccgc cgagaaggac gagcucugag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  4061
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt2)

<400>  4061
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgcgagc uccgcgcccu ccuccucugg ggccgccgcc      120

uccgcccccu ccuccgcgcc cccgcccucg ccgccguccc cggcggcaag cccauccucu      180

gcccccgccg caccaccgcc cagcucggcc cccgccgcaa ccccgccugg ucccuccagg      240

ccggccgccu cuucuccacc cagaccgccg aggacaagga ggagccccuc cacuccauca      300

ucuccuccac cgaguccguc cagggcucca ccuccaagca cgaguuccag gccgagacca      360

agaagcuccu cgacaucguc gcccgcuccc ucuacuccga gaaggagguc uucauccgcg      420

agcucaucuc caacgccucc gacgcccucg agaagcuccg ccacaagcuc gucuccgacg      480

gccaggcccu ccccgagaug gagauccacc uccagaccaa cgccgagaag ggcaccauca      540

ccauccagga caccggcauc ggcaugaccc aggaggagcu cgucuccaac cucggcacca      600

ucgcccgcuc cggcuccaag gccuuccucg acgcccucca gaaccaggcc gaggccuccu      660

ccaagaucau cggccaguuc ggcgucggcu ucuacuccgc cuucaugguc gccgaccgcg      720

ucgaggucua cucccgcucc gccgcccccg gcucccucgg cuaccagugg cucuccgacg      780

gcuccggcgu cuucgagauc gccgaggccu ccggcguccg caccggcacc aagaucauca      840

uccaccucaa guccgacugc aaggaguucu ccuccgaggc ccgcguccgc gacgucguca      900

ccaaguacuc caacuucguc uccuuccccc ucuaccucaa cggccgccgc augaacaccc      960

uccaggccau cuggaugaug gaccccaagg acguccgcga guggcagcac gaggaguucu     1020

accgcuacgu cgcccaggcc cacgacaagc cccgcuacac ccuccacuac aagaccgacg     1080

ccccccucaa cauccgcucc aucuucuacg uccccgacau gaagcccucc auguucgacg     1140

ucucccgcga gcucggcucc uccgucgccc ucuacucccg caagguccuc auccagacca     1200

aggccaccga cauccucccc aaguggcucc gcuucauccg cggcgucguc gacuccgagg     1260

acaucccccu caaccucucc cgcgagcucc uccaggaguc cgcccucauc cgcaagcucc     1320

gcgacguccu ccagcagcgc cucaucaagu ucuucaucga ccaguccaag aaggacgccg     1380

agaaguacgc caaguucuuc gaggacuacg gccucuucau gcgcgagggc aucgucaccg     1440

ccaccgagca ggaggucaag gaggacaucg ccaagcuccu ccgcuacgag uccuccgccc     1500

uccccuccgg ccagcucacc ucccucuccg aguacgccuc ccgcaugcgc gccggcaccc     1560

gcaacaucua cuaccucugc gcccccaacc gccaccucgc cgagcacucc cccuacuacg     1620

aggccaugaa gaagaaggac accgaggucc ucuucugcuu cgagcaguuc gacgagcuca     1680

cccuccucca ccuccgcgag uucgacaaga agaagcucau cuccgucgag accgacaucg     1740

ucgucgacca cuacaaggag gagaaguucg aggaccgcuc ccccgccgcc gagugccucu     1800

ccgagaagga gaccgaggag cucauggccu ggaugcgcaa cguccucggc ucccgcguca     1860

ccaacgucaa ggucacccuc cgccucgaca cccaccccgc cauggucacc guccucgaga     1920

ugggcgccgc ccgccacuuc cuccgcaugc agcagcucgc caagacccag gaggagcgcg     1980

cccagcuccu ccagcccacc cucgagauca acccccgcca cgcccucauc aagaagcuca     2040

accagcuccg cgccuccgag cccggccucg cccagcuccu cgucgaccag aucuacgaga     2100

acgccaugau cgccgccggc cucgucgacg acccccgcgc cauggucggc cgccucaacg     2160

agcuccucgu caaggcccuc gagcgccacu gaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  4062
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt2)

<400>  4062
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagaucu ccucccuccc cacccagcuc uucaagugcu      120

gcuucugcga cuuccucaag gucaagaugc acaccauguc cuccucccac cucuucuacc      180

ucgcccucug ccuccucacc uucaccuccu ccgccaccgc cggccccgag acccucugcg      240

gcgccgagcu cgucgacgcc cuccaguucg ucugcggcga ccgcggcuuc uacuucaaca      300

agcccaccgg cuacggcucc uccucccgcc gcgcccccca gaccggcauc gucgacgagu      360

gcugcuuccg cuccugcgac cuccgccgcc ucgagaugua cugcgccccc cucaagcccg      420

ccaaguccgc ccgcuccguc cgcgcccagc gccacaccga caugcccaag acccagaagg      480

agguccaccu caagaacgcc ucccgcggcu ccgccggcaa caagaacuac cgcaugugag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  4063
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt2)

<400>  4063
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca ugggcaaguc caugcucguc cuccucaccu      120

uccucgccuu cgccuccugc ugcaucgccg ccuaccgccc cuccgagacc cucugcggcg      180

gcgagcucgu cgacacccuc caguucgucu gcggcgaccg cggcuucuac uucucccgcc      240

ccgccucccg cgucucccgc cgcucccgcg gcaucgucga ggagugcugc uuccgcuccu      300

gcgaccucgc ccuccucgag accuacugcg ccacccccgc caaguccgag cgcgacgucu      360

ccaccccccc caccguccuc cccgacaacu ucccccgcua ccccgucggc aaguucuucc      420

aguacgacac cuggaagcag uccacccagc gccuccgccg cggccucccc gcccuccucc      480

gcgcccgccg cggccacguc cucgccaagg agcucgaggc cuuccgcgag gccaagcgcc      540

accgcccccu caucgcccuc cccacccagg accccgccca cggcggcgcc ccccccgaga      600

uggccuccaa ccgcaaguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  4064
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt2)

<400>  4064
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccaccuccgc cuucggcccc gucgccuucu      120

cccucggccu ccuccucguc cuccccgccg ccuuccccgc ccccgucccc cccggcgagg      180

acuccaagga cgucgccgcc ccccaccgcc agccccucac cuccuccgag cgcaucgaca      240

agcagauccg cuacauccuc gacggcaucu ccgcccuccg caaggagacc ugcaacaagu      300

ccaacaugug cgaguccucc aaggaggccc ucgccgagaa caaccucaac cuccccaaga      360

uggccgagaa ggacggcugc uuccaguccg gcuucaacga ggagaccugc cucgucaaga      420

ucaucaccgg ccuccucgag uucgaggucu accucgagua ccuccagaac cgcuucgagu      480

ccuccgagga gcaggcccgc gccguccaga uguccaccaa gguccucauc caguuccucc      540

agaagaaggc caagaaccuc gacgccauca ccacccccga ccccaccacc aacgccuccc      600

uccucaccaa gcuccaggcc cagaaccagu ggcuccagga caugaccacc caccucaucc      660

uccgcuccuu caaggaguuc cuccaguccu cccuccgcgc ccuccgccag augugaggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  4065
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt2)

<400>  4065
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccucu ggcuccgcgg cuuccuccuc gccuccugcu      120

ggaucaucgu ccgcuccucc cccacccccg gcuccgaggg ccacuccgcc gcccccgacu      180

gccccuccug cgcccucgcc gcccucccca aggacguccc caacucccag cccgagaugg      240

ucgaggccgu caagaagcac auccucaaca ugcuccaccu caagaagcgc cccgacguca      300

cccagcccgu ccccaaggcc gcccuccuca acgccauccg caagcuccac gucggcaagg      360

ucggcgagaa cggcuacguc gagaucgagg acgacaucgg ccgccgcgcc gagaugaacg      420

agcucaugga gcagaccucc gagaucauca ccuucgccga guccggcacc gcccgcaaga      480

cccuccacuu cgagaucucc aaggagggcu ccgaccucuc cgucgucgag cgcgccgagg      540

ucuggcucuu ccucaagguc cccaaggcca accgcacccg caccaagguc accauccgcc      600

ucuuccagca gcagaagcac ccccagggcu cccucgacac cggcgaggag gccgaggagg      660

ucggccucaa gggcgagcgc uccgagcucc uccucuccga gaaggucguc gacgcccgca      720

aguccaccug gcacgucuuc cccgucuccu ccuccaucca gcgccuccuc gaccagggca      780

aguccucccu cgacguccgc aucgccugcg agcagugcca ggaguccggc gccucccucg      840

uccuccucgg caagaagaag aagaaggagg aggagggcga gggcaagaag aagggcggcg      900

gcgagggcgg cgccggcgcc gacgaggaga aggagcaguc ccaccgcccc uuccucaugc      960

uccaggcccg ccaguccgag gaccaccccc accgccgccg ccgccgcggc cucgagugcg     1020

acggcaaggu caacaucugc ugcaagaagc aguucuucgu cuccuucaag gacaucggcu     1080

ggaacgacug gaucaucgcc cccuccggcu accacgccaa cuacugcgag ggcgagugcc     1140

ccucccacau cgccggcacc uccggcuccu cccucuccuu ccacuccacc gucaucaacc     1200

acuaccgcau gcgcggccac ucccccuucg ccaaccucaa guccugcugc guccccacca     1260

agcuccgccc cauguccaug cucuacuacg acgacggcca gaacaucauc aagaaggaca     1320

uccagaacau gaucgucgag gagugcggcu gcuccugagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  4066
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt2)

<400>  4066
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccucc ccggccgcgc ccucggcgcc gccugccucc      120

uccuccucgc cgccggcugg cucggccccg aggccugggg cucccccacc ccccccccca      180

cccccgccgc cccccccccc cccccccccc ccggcucccc cggcggcucc caggacaccu      240

gcaccuccug cggcggcuuc cgccgccccg aggagcucgg ccgcgucgac ggcgacuucc      300

ucgaggccgu caagcgccac auccucuccc gccuccagau gcgcggccgc cccaacauca      360

cccacgccgu ccccaaggcc gccaugguca ccgcccuccg caagcuccac gccggcaagg      420

uccgcgagga cggccgcguc gagauccccc accucgacgg ccacgccucc cccggcgccg      480

acggccagga gcgcgucucc gagaucaucu ccuucgccga gaccgacggc cucgccuccu      540

cccgcguccg ccucuacuuc uucaucucca acgagggcaa ccagaaccuc uucgucgucc      600

aggccucccu cuggcucuac cucaagcucc uccccuacgu ccucgagaag ggcucccgcc      660

gcaagguccg cgucaagguc uacuuccagg agcagggcca cggcgaccgc uggaacaugg      720

ucgagaagcg cgucgaccuc aagcgcuccg gcuggcacac cuucccccuc accgaggcca      780

uccaggcccu cuucgagcgc ggcgagcgcc gccucaaccu cgacguccag ugcgacuccu      840

gccaggagcu cgccgucguc cccgucuucg ucgaccccgg cgaggagucc caccgccccu      900

ucgucgucgu ccaggcccgc cucggcgacu cccgccaccg cauccgcaag cgcggccucg      960

agugcgacgg ccgcaccaac cucugcugcc gccagcaguu cuucaucgac uuccgccuca     1020

ucggcuggaa cgacuggauc aucgccccca ccggcuacua cggcaacuac ugcgagggcu     1080

ccugccccgc cuaccucgcc ggcguccccg gcuccgccuc cuccuuccac accgccgucg     1140

ucaaccagua ccgcaugcgc ggccucaacc ccggcaccgu caacuccugc ugcaucccca     1200

ccaagcucuc caccaugucc augcucuacu ucgacgacga guacaacauc gucaagcgcg     1260

acguccccaa caugaucguc gaggagugcg gcugcgccug aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  4067
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt2)

<400>  4067
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccuccgcg uccuccuccu caccgcccuc acccucugcc      120

acggcuucaa ccucgacacc gagaacgcca ugaccuucca ggagaacgcc cgcggcuucg      180

gccaguccgu cguccagcuc cagggcuccc gcgucgucgu cggcgccccc caggagaucg      240

ucgccgccaa ccagcgcggc ucccucuacc agugcgacua cuccaccggc uccugcgagc      300

ccauccgccu ccaggucccc gucgaggccg ucaacauguc ccucggccuc ucccucgccg      360

ccaccaccuc ccccccccag cuccucgccu gcggccccac cguccaccag accugcuccg      420

agaacaccua cgucaagggc cucugcuucc ucuucggcuc caaccuccgc cagcagcccc      480

agaaguuccc cgaggcccuc cgcggcugcc cccaggagga cuccgacauc gccuuccuca      540

ucgacggcuc cggcuccauc aucccccacg acuuccgccg caugaaggag uucgucucca      600

ccgucaugga gcagcucaag aaguccaaga cccucuucuc ccucaugcag uacuccgagg      660

aguuccgcau ccacuucacc uucaaggagu uccagaacaa ccccaacccc cgcucccucg      720

ucaagcccau cacccagcuc cucggccgca cccacaccgc caccggcauc cgcaaggucg      780

uccgcgagcu cuucaacauc accaacggcg cccgcaagaa cgccuucaag auccucgucg      840

ucaucaccga cggcgagaag uucggcgacc cccucggcua cgaggacguc auccccgagg      900

ccgaccgcga gggcgucauc cgcuacguca ucggcgucgg cgacgccuuc cgcuccgaga      960

agucccgcca ggagcucaac accaucgccu ccaagccccc ccgcgaccac gucuuccagg     1020

ucaacaacuu cgaggcccuc aagaccaucc agaaccagcu ccgcgagaag aucuucgcca     1080

ucgagggcac ccagaccggc uccuccuccu ccuucgagca cgagaugucc caggagggcu     1140

ucuccgccgc caucaccucc aacggccccc uccucuccac cgucggcucc uacgacuggg     1200

ccggcggcgu cuuccucuac accuccaagg agaaguccac cuucaucaac augacccgcg     1260

ucgacuccga caugaacgac gccuaccucg gcuacgccgc cgccaucauc cuccgcaacc     1320

gcguccaguc ccucguccuc ggcgcccccc gcuaccagca caucggccuc gucgccaugu     1380

uccgccagaa caccggcaug ugggagucca acgccaacgu caagggcacc cagaucggcg     1440

ccuacuucgg cgccucccuc ugcuccgucg acgucgacuc caacggcucc accgaccucg     1500

uccucaucgg cgccccccac uacuacgagc agacccgcgg cggccagguc uccgucugcc     1560

cccucccccg cggccgcgcc cgcuggcagu gcgacgccgu ccucuacggc gagcagggcc     1620

agcccugggg ccgcuucggc gccgcccuca ccguccucgg cgacgucaac ggcgacaagc     1680

ucaccgacgu cgccaucggc gcccccggcg aggaggacaa ccgcggcgcc gucuaccucu     1740

uccacggcac cuccggcucc ggcaucuccc ccucccacuc ccagcgcauc gccggcucca     1800

agcucucccc ccgccuccag uacuucggcc agucccucuc cggcggccag gaccucacca     1860

uggacggccu cgucgaccuc accgucggcg cccagggcca cguccuccuc cuccgcuccc     1920

agcccguccu ccgcgucaag gccaucaugg aguucaaccc ccgcgagguc gcccgcaacg     1980

ucuucgagug caacgaccag gucgucaagg gcaaggaggc cggcgagguc cgcgucugcc     2040

uccacgucca gaaguccacc cgcgaccgcc uccgcgaggg ccagauccag uccgucguca     2100

ccuacgaccu cgcccucgac uccggccgcc cccacucccg cgccgucuuc aacgagacca     2160

agaacuccac ccgccgccag acccaggucc ucggccucac ccagaccugc gagacccuca     2220

agcuccagcu ccccaacugc aucgaggacc ccgucucccc caucguccuc cgccucaacu     2280

ucucccucgu cggcaccccc cucuccgccu ucggcaaccu ccgccccguc cucgccgagg     2340

acgcccagcg ccucuucacc gcccucuucc ccuucgagaa gaacugcggc aacgacaaca     2400

ucugccagga cgaccucucc aucaccuucu ccuucauguc ccucgacugc cucgucgucg     2460

gcggcccccg cgaguucaac gucaccguca ccguccgcaa cgacggcgag gacuccuacc     2520

gcacccaggu caccuucuuc uucccccucg accucuccua ccgcaagguc uccacccucc     2580

agaaccagcg cucccagcgc uccuggcgcc ucgccugcga guccgccucc uccaccgagg     2640

ucuccggcgc ccucaagucc accuccugcu ccaucaacca ccccaucuuc cccgagaacu     2700

ccgaggucac cuucaacauc accuucgacg ucgacuccaa ggccucccuc ggcaacaagc     2760

uccuccucaa ggccaacguc accuccgaga acaacaugcc ccgcaccaac aagaccgagu     2820

uccagcucga gcuccccguc aaguacgccg ucuacauggu cgucaccucc cacggcgucu     2880

ccaccaagua ccucaacuuc accgccuccg agaacaccuc ccgcgucaug cagcaccagu     2940

accaggucuc caaccucggc cagcgcuccc uccccaucuc ccucgucuuc cucguccccg     3000

uccgccucaa ccagaccguc aucugggacc gcccccaggu caccuucucc gagaaccucu     3060

ccuccaccug ccacaccaag gagcgccucc ccucccacuc cgacuuccuc gccgagcucc     3120

gcaaggcccc cgucgucaac ugcuccaucg ccgucugcca gcgcauccag ugcgacaucc     3180

ccuucuucgg cauccaggag gaguucaacg ccacccucaa gggcaaccuc uccuucgacu     3240

gguacaucaa gaccucccac aaccaccucc ucaucgucuc caccgccgag auccucuuca     3300

acgacuccgu cuucacccuc cuccccggcc agggcgccuu cguccgcucc cagaccgaga     3360

ccaaggucga gcccuucgag guccccaacc cccucccccu caucgucggc uccuccgucg     3420

gcggccuccu ccuccucgcc cucaucaccg ccgcccucua caagcucggc uucuucaagc     3480

gccaguacaa ggacaugaug uccgagggcg gcccccccgg cgccgagccc cagugaggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  4068
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt2)

<400>  4068
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucccuca agacccuccc cuuccuccuc cuccuccacg      120

uccagaucuc caaggccuuc cccgucuccu ccaaggagaa gaacaccaag accguccagg      180

acuaccucga gaaguucuac cagcuccccu ccaaccagua ccaguccacc cgcaagaacg      240

gcaccaacgu caucgucgag aagcucaagg agaugcagcg cuucuucggc cucaacguca      300

ccggcaagcc caacgaggag acccucgaca ugaugaagaa gccccgcugc ggcguccccg      360

acuccggcgg cuucaugcuc acccccggca accccaagug ggagcgcacc aaccucaccu      420

accgcauccg caacuacacc ccccagcucu ccgaggccga ggucgagcgc gccaucaagg      480

acgccuucga gcucuggucc gucgccuccc cccucaucuu cacccgcauc ucccagggcg      540

aggccgacau caacaucgcc uucuaccagc gcgaccacgg cgacaacucc cccuucgacg      600

gccccaacgg cauccucgcc cacgccuucc agcccggcca gggcaucggc ggcgacgccc      660

acuucgacgc cgaggagacc uggaccaaca ccuccgccaa cuacaaccuc uuccucgucg      720

ccgcccacga guucggccac ucccucggcc ucgcccacuc cuccgacccc ggcgcccuca      780

uguaccccaa cuacgccuuc cgcgagaccu ccaacuacuc ccucccccag gacgacaucg      840

acggcaucca ggccaucuac ggccucuccu ccaaccccau ccagcccacc ggccccucca      900

cccccaagcc cugcgacccc ucccucaccu ucgacgccau caccacccuc cgcggcgaga      960

uccucuucuu caaggaccgc uacuucuggc gccgccaccc ccagcuccag cgcgucgaga     1020

ugaacuucau cucccucuuc uggcccuccc uccccaccgg cauccaggcc gccuacgagg     1080

acuucgaccg cgaccucauc uuccucuuca agggcaacca guacugggcc cucuccggcu     1140

acgacauccu ccagggcuac cccaaggaca ucuccaacua cggcuucccc uccuccgucc     1200

aggccaucga cgccgccguc uucuaccgcu ccaagaccua cuucuucguc aacgaccagu     1260

ucuggcgcua cgacaaccag cgccaguuca uggagcccgg cuaccccaag uccaucuccg     1320

gcgccuuccc cggcaucgag uccaaggucg acgccgucuu ccagcaggag cacuucuucc     1380

acgucuucuc cggcccccgc uacuacgccu ucgaccucau cgcccagcgc gucacccgcg     1440

ucgcccgcgg caacaagugg cucaacugcc gcuacggcug aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  4069
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt2)

<400>  4069
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucccucuggc agccccucgu ccucguccuc cucguccucg      120

gcugcugcuu cgccgccccc cgccagcgcc aguccacccu cguccucuuc cccggcgacc      180

uccgcaccaa ccucaccgac cgccagcucg ccgaggagua ccucuaccgc uacggcuaca      240

cccgcgucgc cgagaugcgc ggcgagucca agucccucgg ccccgcccuc cuccuccucc      300

agaagcagcu cucccucccc gagaccggcg agcucgacuc cgccacccuc aaggccaugc      360

gcaccccccg cugcggcguc cccgaccucg gccgcuucca gaccuucgag ggcgaccuca      420

aguggcacca ccacaacauc accuacugga uccagaacua cuccgaggac cucccccgcg      480

ccgucaucga cgacgccuuc gcccgcgccu ucgcccucug guccgccguc accccccuca      540

ccuucacccg cgucuacucc cgcgacgccg acaucgucau ccaguucggc gucgccgagc      600

acggcgacgg cuaccccuuc gacggcaagg acggccuccu cgcccacgcc uucccccccg      660

gccccggcau ccagggcgac gcccacuucg acgacgacga gcucuggucc cucggcaagg      720

gcgucgucgu ccccacccgc uucggcaacg ccgacggcgc cgccugccac uuccccuuca      780

ucuucgaggg ccgcuccuac uccgccugca ccaccgacgg ccgcuccgac ggccuccccu      840

ggugcuccac caccgccaac uacgacaccg acgaccgcuu cggcuucugc cccuccgagc      900

gccucuacac ccaggacggc aacgccgacg gcaagcccug ccaguucccc uucaucuucc      960

agggccaguc cuacuccgcc ugcaccaccg acggccgcuc cgacggcuac cgcuggugcg     1020

ccaccaccgc caacuacgac cgcgacaagc ucuucggcuu cugccccacc cgcgccgacu     1080

ccaccgucau gggcggcaac uccgccggcg agcucugcgu cuuccccuuc accuuccucg     1140

gcaaggagua cuccaccugc accuccgagg gccgcggcga cggccgccuc uggugcgcca     1200

ccaccuccaa cuucgacucc gacaagaagu ggggcuucug ccccgaccag ggcuacuccc     1260

ucuuccucgu cgccgcccac gaguucggcc acgcccucgg ccucgaccac uccuccgucc     1320

ccgaggcccu cauguacccc auguaccgcu ucaccgaggg ccccccccuc cacaaggacg     1380

acgucaacgg cauccgccac cucuacggcc cccgccccga gcccgagccc cgccccccca     1440

ccaccaccac cccccagccc accgcccccc ccaccgucug ccccaccggc ccccccaccg     1500

uccaccccuc cgagcgcccc accgccggcc ccaccggccc ccccuccgcc ggccccaccg     1560

gcccccccac cgccggcccc uccaccgcca ccaccguccc ccucuccccc gucgacgacg     1620

ccugcaacgu caacaucuuc gacgccaucg ccgagaucgg caaccagcuc uaccucuuca     1680

aggacggcaa guacuggcgc uucuccgagg gccgcggcuc ccgcccccag ggccccuucc     1740

ucaucgccga caaguggccc gcccuccccc gcaagcucga cuccgucuuc gaggagcgcc     1800

ucuccaagaa gcucuucuuc uucuccggcc gccaggucug ggucuacacc ggcgccuccg     1860

uccucggccc ccgccgccuc gacaagcucg gccucggcgc cgacgucgcc caggucaccg     1920

gcgcccuccg cuccggccgc ggcaagaugc uccucuucuc cggccgccgc cucuggcgcu     1980

ucgacgucaa ggcccagaug gucgaccccc gcuccgccuc cgaggucgac cgcauguucc     2040

ccggcguccc ccucgacacc cacgacgucu uccaguaccg cgagaaggcc uacuucugcc     2100

aggaccgcuu cuacuggcgc gucuccuccc gcuccgagcu caaccagguc gaccaggucg     2160

gcuacgucac cuacgacauc cuccagugcc ccgaggacug aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  4070
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt2)

<400>  4070
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg uccucgccgc cuuccucuuc cucuccugga      120

cccacugccg cgcccucccc cuccccuccg gcggcgacga ggacgaccuc uccgaggagg      180

accuccaguu cgccgagcgc uaccuccgcu ccuacuacca ccccaccaac cucgccggca      240

uccucaagga gaacgccgcc uccuccauga ccgagcgccu ccgcgagaug caguccuucu      300

ucggccucga ggucaccggc aagcucgacg acaacacccu cgacgucaug aagaagcccc      360

gcugcggcgu ccccgacguc ggcgaguaca acgucuuccc ccgcacccuc aaguggucca      420

agaugaaccu caccuaccgc aucgucaacu acacccccga caugacccac uccgaggucg      480

agaaggccuu caagaaggcc uucaaggucu gguccgacgu caccccccuc aacuucaccc      540

gccuccacga cggcaucgcc gacaucauga ucuccuucgg caucaaggag cacggcgacu      600

ucuaccccuu cgacggcccc uccggccucc ucgcccacgc cuuccccccc ggccccaacu      660

acggcggcga cgcccacuuc gacgacgacg agaccuggac cuccuccucc aagggcuaca      720

accucuuccu cgucgccgcc cacgaguucg gccacucccu cggccucgac cacuccaagg      780

accccggcgc ccucauguuc cccaucuaca ccuacaccgg caagucccac uucaugcucc      840

ccgacgacga cguccagggc auccaguccc ucuacggccc cggcgacgag gaccccaacc      900

ccaagcaccc caagaccccc gacaagugcg accccucccu cucccucgac gccaucaccu      960

cccuccgcgg cgagaccaug aucuucaagg accgcuucuu cuggcgccuc cacccccagc     1020

aggucgacgc cgagcucuuc cucaccaagu ccuucuggcc cgagcucccc aaccgcaucg     1080

acgccgccua cgagcacccc ucccacgacc ucaucuucau cuuccgcggc cgcaaguucu     1140

gggcccucaa cggcuacgac auccucgagg gcuaccccaa gaagaucucc gagcucggcc     1200

uccccaagga ggucaagaag aucuccgccg ccguccacuu cgaggacacc ggcaagaccc     1260

uccucuucuc cggcaaccag gucuggcgcu acgacgacac caaccacauc auggacaagg     1320

acuacccccg ccucaucgag gaggacuucc ccggcaucgg cgacaagguc gacgccgucu     1380

acgagaagaa cggcuacauc uacuucuuca acggccccau ccaguucgag uacuccaucu     1440

gguccaaccg caucguccgc gucaugcccg ccaacuccau ccucuggugc ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4071
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt2)

<400>  4071
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acaccaccga ggacuacgac accaccaccg      120

aguucgacua cggcgacgcc acccccugcc agaaggucaa cgagcgcgcc uucggcgccc      180

agcuccuccc cccccucuac ucccucgucu ucgucaucgg ccucgucggc aacauccucg      240

ucguccucgu ccucguccag uacaagcgcc ucaagaacau gaccuccauc uaccuccuca      300

accucgccau cuccgaccuc cucuuccucu ucacccuccc cuucuggauc gacuacaagc      360

ucaaggacga cugggucuuc ggcgacgcca ugugcaagau ccucuccggc uucuacuaca      420

ccggccucua cuccgagauc uucuucauca uccuccucac caucgaccgc uaccucgcca      480

ucguccacgc cgucuucgcc cuccgcgccc gcaccgucac cuucggcguc aucaccucca      540

ucaucaucug ggcccucgcc auccucgccu ccaugcccgg ccucuacuuc uccaagaccc      600

agugggaguu cacccaccac accugcuccc uccacuuccc ccacgagucc cuccgcgagu      660

ggaagcucuu ccaggcccuc aagcucaacc ucuucggccu cguccucccc cuccucguca      720

ugaucaucug cuacaccggc aucaucaaga uccuccuccg ccgccccaac gagaagaagu      780

ccaaggccgu ccgccucauc uucgucauca ugaucaucuu cuuccucuuc uggacccccu      840

acaaccucac cauccucauc uccgucuucc aggacuuccu cuucacccac gagugcgagc      900

agucccgcca ccucgaccuc gccguccagg ucaccgaggu caucgccuac acccacugcu      960

gcgucaaccc cgucaucuac gccuucgucg gcgagcgcuu ccgcaaguac cuccgccagc     1020

ucuuccaccg ccgcgucgcc guccaccucg ucaaguggcu ccccuuccuc uccgucgacc     1080

gccucgagcg cgucuccucc accucccccu ccaccggcga gcacgagcuc uccgccggcu     1140

ucugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  4072
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt2)

<400>  4072
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcacccucg ccugccuccu ccuccucggc ugcggcuacc      120

ucgcccacgu ccucgccgag gaggccgaga ucccccgcga ggucaucgag cgccucgccc      180

gcucccagau ccacuccauc cgcgaccucc agcgccuccu cgagaucgac uccgucggcu      240

ccgaggacuc ccucgacacc ucccuccgcg cccacggcgu ccacgccacc aagcacgucc      300

ccgagaagcg cccccucccc auccgccgca agcgcuccau cgaggaggcc guccccgccg      360

ucugcaagac ccgcaccguc aucuacgaga ucccccgcuc ccaggucgac cccaccuccg      420

ccaacuuccu caucuggccc cccugcgucg aggucaagcg cugcaccggc ugcugcaaca      480

ccuccuccgu caagugccag cccucccgcg uccaccaccg cuccgucaag gucgccaagg      540

ucgaguacgu ccgcaagaag cccaagcuca aggaggucca gguccgccuc gaggagcacc      600

ucgagugcgc cugcgccacc accucccuca accccgacua ccgcgaggag gacaccggcc      660

gcccccgcga guccggcaag aagcgcaagc gcaagcgccu caagcccacc ugaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  4073
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt2)

<400>  4073
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaccgcugcu gggcccucuu ccucucccuc ugcugcuacc      120

uccgccucgu cuccgccgag ggcgacccca uccccgagga gcucuacgag augcucuccg      180

accacuccau ccgcuccuuc gacgaccucc agcgccuccu ccacggcgac cccggcgagg      240

aggacggcgc cgagcucgac cucaacauga cccgcuccca cuccggcggc gagcucgagu      300

cccucgcccg cggccgccgc ucccucggcu cccucaccau cgccgagccc gccaugaucg      360

ccgagugcaa gacccgcacc gaggucuucg agaucucccg ccgccucauc gaccgcacca      420

acgccaacuu ccucgucugg ccccccugcg ucgaggucca gcgcugcucc ggcugcugca      480

acaaccgcaa cguccagugc cgccccaccc agguccagcu ccgccccguc cagguccgca      540

agaucgagau cguccgcaag aagcccaucu ucaagaaggc caccgucacc cucgaggacc      600

accucgccug caagugcgag accgucgccg ccgcccgccc cgucacccgc ucccccggcg      660

gcucccagga gcagcgcgcc aagacccccc agacccgcgu caccauccgc accguccgcg      720

uccgccgccc ccccaagggc aagcaccgca aguucaagca cacccacgac aagaccgccc      780

ucaaggagac ccucggcgcc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  4074
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt2)

<400>  4074
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucccucuucg gccuccuccu ccucaccucc gcccucgccg      120

gccagcgcca gggcacccag gccgagucca accucuccuc caaguuccag uucuccucca      180

acaaggagca gaacggcguc caggaccccc agcacgagcg caucaucacc gucuccacca      240

acggcuccau ccacuccccc cgcuuccccc acaccuaccc ccgcaacacc guccucgucu      300

ggcgccucgu cgccgucgag gagaacgucu ggauccagcu caccuucgac gagcgcuucg      360

gccucgagga ccccgaggac gacaucugca aguacgacuu cgucgagguc gaggagcccu      420

ccgacggcac cauccucggc cgcuggugcg gcuccggcac cguccccggc aagcagaucu      480

ccaagggcaa ccagauccgc auccgcuucg ucuccgacga guacuucccc uccgagcccg      540

gcuucugcau ccacuacaac aucgucaugc cccaguucac cgaggccguc ucccccuccg      600

uccucccccc cuccgcccuc ccccucgacc uccucaacaa cgccaucacc gccuucucca      660

cccucgagga ccucauccgc uaccucgagc ccgagcgcug gcagcucgac cucgaggacc      720

ucuaccgccc caccuggcag cuccucggca aggccuucgu cuucggccgc aagucccgcg      780

ucgucgaccu caaccuccuc accgaggagg uccgccucua cuccugcacc ccccgcaacu      840

ucuccgucuc cauccgcgag gagcucaagc gcaccgacac caucuucugg cccggcugcc      900

uccucgucaa gcgcugcggc ggcaacugcg ccugcugccu ccacaacugc aacgagugcc      960

agugcguccc cuccaagguc accaagaagu accacgaggu ccuccagcuc cgccccaaga     1020

ccggcguccg cggccuccac aagucccuca ccgacgucgc ccucgagcac cacgaggagu     1080

gcgacugcgu cugccgcggc uccaccggcg gcugaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  4075
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt2)

<400>  4075
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgccuca ucuucgucua cacccucauc ugcgccaacu      120

ucugcuccug ccgcgacacc uccgccaccc cccaguccgc cuccaucaag gcccuccgca      180

acgccaaccu ccgccgcgac gaccucuacc gccgcgacga gaccauccag gucaagggca      240

acggcuacgu ccaguccccc cgcuucccca acuccuaccc ccgcaaccuc cuccucaccu      300

ggcgccucca cucccaggag aacacccgca uccagcucgu cuucgacaac caguucggcc      360

ucgaggaggc cgagaacgac aucugccgcu acgacuucgu cgaggucgag gacaucuccg      420

agaccuccac caucauccgc ggccgcuggu gcggccacaa ggaggucccc ccccgcauca      480

agucccgcac caaccagauc aagaucaccu ucaaguccga cgacuacuuc gucgccaagc      540

ccggcuucaa gaucuacuac ucccuccucg aggacuucca gcccgccgcc gccuccgaga      600

ccaacuggga guccgucacc uccuccaucu ccggcgucuc cuacaacucc cccuccguca      660

ccgaccccac ccucaucgcc gacgcccucg acaagaagau cgccgaguuc gacaccgucg      720

aggaccuccu caaguacuuc aaccccgagu ccuggcagga ggaccucgag aacauguacc      780

ucgacacccc ccgcuaccgc ggccgcuccu accacgaccg caaguccaag gucgaccucg      840

accgccucaa cgacgacgcc aagcgcuacu ccugcacccc ccgcaacuac uccgucaaca      900

uccgcgagga gcucaagcuc gccaacgucg ucuucuuccc ccgcugccuc cucguccagc      960

gcugcggcgg caacugcggc ugcggcaccg ucaacuggcg cuccugcacc ugcaacuccg     1020

gcaagaccgu caagaaguac cacgaggucc uccaguucga gcccggccac aucaagcgcc     1080

gcggccgcgc caagaccaug gcccucgucg acauccagcu cgaccaccac gagcgcugcg     1140

acugcaucug cuccucccgc cccccccgcu gaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  4076
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt2)

<400>  4076
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccacu ccaaguuccc cgccgccggc augucccgcc      120

cccucgacac cucccuccgc cucaagaccu ucuccuccaa guccgaguac cagcucgucg      180

ucaacgccgu ccgcaagcuc caggaguccg gcuucuacug guccgccguc accggcggcg      240

aggccaaccu ccuccucucc gccgagcccg ccggcaccuu ccucauccgc gacuccuccg      300

accagcgcca cuucuucacc cucuccguca agacccaguc cggcaccaag aaccuccgca      360

uccagugcga gggcggcucc uucucccucc aguccgaccc ccgcuccacc cagcccgucc      420

cccgcuucga cugcguccuc aagcucgucc accacuacau gccccccccc ggcgcccccu      480

ccuuccccuc cccccccacc gagcccuccu ccgagguccc cgagcagccc uccgcccagc      540

cccuccccgg cucccccccc cgccgcgccu acuacaucua cuccggcggc gagaagaucc      600

cccucguccu cucccgcccc cucuccucca acgucgccac ccuccagcac cucugccgca      660

agaccgucaa cggccaccuc gacuccuacg agaaggucac ccagcucccc ggccccaucc      720

gcgaguuccu cgaccaguac gacgcccccc ucugaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  4077
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt2)

<400>  4077
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guccccuccg ccggccagcu cgcccucuuc gcccucggca      120

ucguccucgc cgccugccag gcccucgaga acuccaccuc cccccucucc gccgaccccc      180

ccgucgccgc cgccgucguc ucccacuuca acgacugccc cgacucccac acccaguucu      240

gcuuccacgg caccugccgc uuccucgucc aggaggacaa gcccgccugc gucugccacu      300

ccggcuacgu cggcgcccgc ugcgagcacg ccgaccuccu cgccgucguc gccgccuccc      360

agaagaagca ggccaucacc gcccucgucg ucgucuccau cgucgcccuc gccguccuca      420

ucaucaccug cguccucauc cacugcugcc agguccgcaa gcacugcgag uggugccgcg      480

cccucaucug ccgccacgag aagcccuccg cccuccucaa gggccgcacc gccugcugcc      540

acuccgagac cgucgucuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  4078
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt2)

<400>  4078
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccccuccg gccuccgccu ccucccccuc cuccuccccc      120

uccucuggcu ccucguccuc acccccggcc gccccgccgc cggccucucc accugcaaga      180

ccaucgacau ggagcucguc aagcgcaagc gcaucgaggc cauccgcggc cagauccucu      240

ccaagcuccg ccucgccucc ccccccuccc agggcgaggu cccccccggc ccccuccccg      300

aggccguccu cgcccucuac aacuccaccc gcgaccgcgu cgccggcgag uccgccgagc      360

ccgagcccga gcccgaggcc gacuacuacg ccaaggaggu cacccgcguc cucauggucg      420

agacccacaa cgagaucuac gacaaguuca agcaguccac ccacuccauc uacauguucu      480

ucaacaccuc cgagcuccgc gaggccgucc ccgagcccgu ccuccucucc cgcgccgagc      540

uccgccuccu ccgccucaag cucaaggucg agcagcacgu cgagcucuac cagaaguacu      600

ccaacaacuc cuggcgcuac cucuccaacc gccuccucgc ccccuccgac ucccccgagu      660

ggcucuccuu cgacgucacc ggcgucgucc gccaguggcu cucccgcggc ggcgagaucg      720

agggcuuccg ccucuccgcc cacugcuccu gcgacucccg cgacaacacc cuccaggucg      780

acaucaacgg cuucaccacc ggccgccgcg gcgaccucgc caccauccac ggcaugaacc      840

gccccuuccu ccuccucaug gccacccccc ucgagcgcgc ccagcaccuc caguccuccc      900

gccaccgccg cgcccucgac accaacuacu gcuucuccuc caccgagaag aacugcugcg      960

uccgccagcu cuacaucgac uuccgcaagg accucggcug gaaguggauc cacgagccca     1020

agggcuacca cgccaacuuc ugccucggcc ccugccccua caucuggucc cucgacaccc     1080

aguacuccaa gguccucgcc cucuacaacc agcacaaccc cggcgccucc gccgcccccu     1140

gcugcguccc ccaggcccuc gagccccucc ccaucgucua cuacgucggc cgcaagccca     1200

aggucgagca gcucuccaac augaucgucc gcuccugcaa gugcuccuga ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  4079
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt2)

<400>  4079
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uccucuccgc cuuccucauc cuccaccucg      120

ucaccgucgc ccucucccuc uccaccugcu ccacccucga cauggaccag uucaugcgca      180

agcgcaucga ggccauccgc ggccagaucc ucuccaagcu caagcucacc uccccccccg      240

aggacuaccc cgagcccgag gagguccccc ccgaggucau cuccaucuac aacuccaccc      300

gcgaccuccu ccaggagaag gccucccgcc gcgccgccgc cugcgagcgc gagcgcuccg      360

acgaggagua cuacgccaag gaggucuaca agaucgacau gccccccuuc uuccccuccg      420

agaacgccau cccccccacc uucuaccgcc ccuacuuccg caucguccgc uucgacgucu      480

ccgccaugga gaagaacgcc uccaaccucg ucaaggccga guuccgcguc uuccgccucc      540

agaaccccaa ggcccgcguc cccgagcagc gcaucgagcu cuaccagauc cucaagucca      600

aggaccucac cucccccacc cagcgcuaca ucgacuccaa ggucgucaag acccgcgccg      660

agggcgagug gcucuccuuc gacgucaccg acgccgucca cgaguggcuc caccacaagg      720

accgcaaccu cggcuucaag aucucccucc acugccccug cugcaccuuc guccccucca      780

acaacuacau cauccccaac aaguccgagg agcucgaggc ccgcuucgcc ggcaucgacg      840

gcaccuccac cuacaccucc ggcgaccaga agaccaucaa guccacccgc aagaagaacu      900

ccggcaagac cccccaccuc cuccucaugc uccuccccuc cuaccgccuc gagucccagc      960

agaccaaccg ccgcaagaag cgcgcccucg acgccgccua cugcuuccgc aacguccagg     1020

acaacugcug ccuccgcccc cucuacaucg acuucaagcg cgaccucggc uggaagugga     1080

uccacgagcc caagggcuac aacgccaacu ucugcgccgg cgccugcccc uaccucuggu     1140

ccuccgacac ccagcacucc cgcguccucu cccucuacaa caccaucaac cccgaggccu     1200

ccgccucccc cugcugcguc ucccaggacc ucgagccccu caccauccuc uacuacaucg     1260

gcaagacccc caagaucgag cagcucucca acaugaucgu caaguccugc aagugcuccu     1320

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  4080
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt2)

<400>  4080
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacc uccagcgcgc ccucgucguc cucgcccucc      120

ucaacuucgc caccgucucc cucucccucu ccaccugcac cacccucgac uucggccaca      180

ucaagaagaa gcgcgucgag gccauccgcg gccagauccu cuccaagcuc cgccucaccu      240

ccccccccga gcccaccguc augacccacg uccccuacca gguccucgcc cucuacaacu      300

ccacccgcga gcuccucgag gagaugcacg gcgagcgcga ggagggcugc acccaggaga      360

acaccgaguc cgaguacuac gccaaggaga uccacaaguu cgacaugauc cagggccucg      420

ccgagcacaa cgagcucgcc gucugcccca agggcaucac cuccaagguc uuccgcuuca      480

acgucuccuc cgucgagaag aaccgcacca accucuuccg cgccgaguuc cgcguccucc      540

gcguccccaa ccccuccucc aagcgcaacg agcagcgcau cgagcucuuc cagauccucc      600

gccccgacga gcacaucgcc aagcagcgcu acaucggcgg caagaaccuc cccacccgcg      660

gcaccgccga guggcucucc uucgacguca ccgacaccgu ccgcgagugg cuccuccgcc      720

gcgaguccaa ccucggccuc gagaucucca uccacugccc cugccacacc uuccagccca      780

acggcgacau ccucgagaac auccacgagg ucauggagau caaguucaag ggcgucgaca      840

acgaggacga ccacggccgc ggcgaccucg gccgccucaa gaagcagaag gaccaccaca      900

acccccaccu cauccucaug augauccccc cccaccgccu cgacaacccc ggccagggcg      960

gccagcgcaa gaagcgcgcc cucgacacca acuacugcuu ccgcaaccuc gaggagaacu     1020

gcugcguccg cccccucuac aucgacuucc gccaggaccu cggcuggaag uggguccacg     1080

agcccaaggg cuacuacgcc aacuucugcu ccggccccug ccccuaccuc cgcuccgccg     1140

acaccaccca cuccaccguc cucggccucu acaacacccu caaccccgag gccuccgccu     1200

cccccugcug cgucccccag gaccucgagc cccucaccau ccucuacuac gucggccgca     1260

cccccaaggu cgagcagcuc uccaacaugg ucgucaaguc cugcaagugc uccugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4081
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt2)

<400>  4081
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccccgucg ccgucugggc cgcccucgcc gucggccucg      120

agcucugggc cgccgcccac gcccuccccg cccaggucgc cuucaccccc uacgcccccg      180

agcccggcuc caccugccgc cuccgcgagu acuacgacca gaccgcccag augugcugcu      240

ccaagugcuc ccccggccag cacgccaagg ucuucugcac caagaccucc gacaccgucu      300

gcgacuccug cgaggacucc accuacaccc agcucuggaa cugggucccc gagugccucu      360

ccugcggcuc ccgcugcucc uccgaccagg ucgagaccca ggccugcacc cgcgagcaga      420

accgcaucug caccugccgc cccggcuggu acugcgcccu cuccaagcag gagggcugcc      480

gccucugcgc cccccuccgc aagugccgcc ccggcuucgg cgucgcccgc cccggcaccg      540

agaccuccga cgucgucugc aagcccugcg cccccggcac cuucuccaac accaccuccu      600

ccaccgacau cugccgcccc caccagaucu gcaacgucgu cgccaucccc ggcaacgccu      660

ccauggacgc cgucugcacc uccaccuccc ccacccgcuc cauggccccc ggcgccgucc      720

accuccccca gcccgucucc acccgcuccc agcacaccca gcccaccccc gagcccucca      780

ccgcccccuc caccuccuuc cuccucccca ugggccccuc cccccccgcc gagggcucca      840

ccggcgacuu cgcccucccc gucggccuca ucgucggcgu caccgcccuc ggccuccuca      900

ucaucggcgu cgucaacugc gucaucauga cccaggucaa gaagaagccc cucugccucc      960

agcgcgaggc caaggucccc caccuccccg ccgacaaggc ccgcggcacc cagggccccg     1020

agcagcagca ccuccucauc accgcccccu ccuccuccuc cuccucccuc gaguccuccg     1080

ccuccgcccu cgaccgccgc gcccccaccc gcaaccagcc ccaggccccc ggcgucgagg     1140

ccuccggcgc cggcgaggcc cgcgccucca ccggcuccuc cgacuccucc cccggcggcc     1200

acggcaccca ggucaacguc accugcaucg ucaacgucug cuccuccucc gaccacuccu     1260

cccagugcuc cucccaggcc uccuccacca ugggcgacac cgacuccucc cccuccgagu     1320

cccccaagga cgagcagguc cccuucucca aggaggagug cgccuuccgc ucccagcucg     1380

agacccccga gacccuccuc ggcuccaccg aggagaagcc ccucccccuc ggcguccccg     1440

acgccggcau gaagcccucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  4082
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt2)

<400>  4082
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgucaugc gccucuuccc cugcuuccuc cagcuccucg      120

ccggccucgc ccuccccgcc gucccccccc agcagugggc ccucuccgcc ggcaacggcu      180

ccuccgaggu cgaggucguc cccuuccagg aggucugggg ccgcuccuac ugccgcgccc      240

ucgagcgccu cgucgacguc gucuccgagu accccuccga ggucgagcac auguucuccc      300

ccuccugcgu cucccuccuc cgcugcaccg gcugcugcgg cgacgagaac cuccacugcg      360

uccccgucga gaccgccaac gucaccaugc agcuccucaa gauccgcucc ggcgaccgcc      420

ccuccuacgu cgagcucacc uucucccagc acguccgcug cgagugccgc ccccuccgcg      480

agaagaugaa gcccgagcgc cgccgcccca agggccgcgg caagcgccgc cgcgagaagc      540

agcgccccac cgacugccac cucugcggcg acgccguccc ccgccgcuga ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  4083
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt2)

<400>  4083
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgaccgcc agaccgacac cgcccccucc cccuccuacc      120

accuccuccc cggccgccgc cgcaccgucg acgccgccgc cucccgcggc cagggccccg      180

agcccgcccc cggcggcggc gucgagggcg ucggcgcccg cggcgucgcc cucaagcucu      240

ucguccagcu ccucggcugc ucccgcuucg gcggcgccgu cguccgcgcc ggcgaggccg      300

agcccuccgg cgccgcccgc uccgccuccu ccggccgcga ggagccccag cccgaggagg      360

gcgaggagga ggaggagaag gaggaggagc gcggccccca guggcgccuc ggcgcccgca      420

agcccggcuc cuggaccggc gaggccgccg ucugcgccga cuccgccccc gccgcccgcg      480

ccccccaggc ccucgcccgc gccuccggcc gcggcggccg cgucgcccgc cgcggcgccg      540

aggaguccgg ccccccccac ucccccuccc gccgcggcuc cgccucccgc gccggccccg      600

gccgcgccuc cgagaccaug aacuuccucc ucuccugggu ccacuggucc cucgcccucc      660

uccucuaccu ccaccacgcc aagugguccc aggccgcccc cauggccgag ggcggcggcc      720

agaaccacca cgaggucguc aaguucaugg acgucuacca gcgcuccuac ugccacccca      780

ucgagacccu cgucgacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      840

ccuccugcgu cccccucaug cgcugcggcg gcugcugcaa cgacgagggc cucgagugcg      900

uccccaccga ggaguccaac aucaccaugc agaucaugcg caucaagccc caccagggcc      960

agcacaucgg cgagaugucc uuccuccagc acaacaagug cgagugccgc cccaagaagg     1020

accgcgcccg ccaggagaag aaguccgucc gcggcaaggg caagggccag aagcgcaagc     1080

gcaagaaguc ccgcuacaag uccugguccg ucuacgucgg cgcccgcugc ugccucaugc     1140

ccuggucccu ccccggcccc caccccugcg gccccugcuc cgagcgccgc aagcaccucu     1200

ucguccagga cccccagacc ugcaagugcu ccugcaagaa caccgacucc cgcugcaagg     1260

cccgccagcu cgagcucaac gagcgcaccu gccgcugcga caagccccgc cgcugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4084
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt2)

<400>  4084
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc ucuccugggu ccacuggucc cucgcccucc      120

uccucuaccu ccaccacgcc aagugguccc aggccgcccc cauggccgag ggcggcggcc      180

agaaccacca cgaggucguc aaguucaugg acgucuacca gcgcuccuac ugccacccca      240

ucgagacccu cgucgacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      300

ccuccugcgu cccccucaug cgcugcggcg gcugcugcaa cgacgagggc cucgagugcg      360

uccccaccga ggaguccaac aucaccaugc agaucaugcg caucaagccc caccagggcc      420

agcacaucgg cgagaugucc uuccuccagc acaacaagug cgagugccgc cccaagaagg      480

accgcgcccg ccaggagaag aaguccgucc gcggcaaggg caagggccag aagcgcaagc      540

gcaagaaguc ccgcuacaag uccugguccg ucuacgucgg cgcccgcugc ugccucaugc      600

ccuggucccu ccccggcccc caccccugcg gccccugcuc cgagcgccgc aagcaccucu      660

ucguccagga cccccagacc ugcaagugcu ccugcaagaa caccgacucc cgcugcaagg      720

cccgccagcu cgagcucaac gagcgcaccu gccgcugcga caagccccgc cgcugaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  4085
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt2)

<400>  4085
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccccccucc uccgccgccu ccuccucgcc gcccuccucc      120

agcucgcccc cgcccaggcc cccgucuccc agcccgacgc ccccggccac cagcgcaagg      180

ucgucuccug gaucgacguc uacacccgcg ccaccugcca gccccgcgag gucgucgucc      240

cccucaccgu cgagcucaug ggcaccgucg ccaagcagcu cguccccucc ugcgucaccg      300

uccagcgcug cggcggcugc ugccccgacg acggccucga gugcgucccc accggccagc      360

accagguccg caugcagauc cucaugaucc gcuaccccuc cucccagcuc ggcgagaugu      420

cccucgagga gcacucccag ugcgagugcc gccccaagaa gaaggacucc gccgucaagc      480

ccgaccgcgc cgccaccccc caccaccgcc cccagccccg cuccgucccc ggcugggacu      540

ccgcccccgg cgcccccucc cccgccgaca ucacccaccc cacccccgcc cccggccccu      600

ccgcccacgc cgcccccucc accaccuccg cccucacccc cggccccgcc gccgccgccg      660

ccgacgccgc cgccuccucc gucgccaagg gcggcgccug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  4086
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt2)

<400>  4086
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuccucg gcuucuucuc cgucgccugc ucccuccucg      120

ccgccgcccu ccuccccggc ccccgcgagg cccccgccgc cgccgccgcc uucgaguccg      180

gccucgaccu cuccgacgcc gagcccgacg ccggcgaggc caccgccuac gccuccaagg      240

accucgagga gcagcuccgc uccgucuccu ccgucgacga gcucaugacc guccucuacc      300

ccgaguacug gaagauguac aagugccagc uccgcaaggg cggcuggcag cacaaccgcg      360

agcaggccaa ccucaacucc cgcaccgagg agaccaucaa guucgccgcc gcccacuaca      420

acaccgagau ccucaagucc aucgacaacg aguggcgcaa gacccagugc augccccgcg      480

aggucugcau cgacgucggc aaggaguucg gcgucgccac caacaccuuc uucaagcccc      540

ccugcgucuc cgucuaccgc ugcggcggcu gcugcaacuc cgagggccuc cagugcauga      600

acaccuccac cuccuaccuc uccaagaccc ucuucgagau caccgucccc cucucccagg      660

gccccaagcc cgucaccauc uccuucgcca accacaccuc cugccgcugc auguccaagc      720

ucgacgucua ccgccagguc cacuccauca uccgccgcuc ccuccccgcc acccuccccc      780

agugccaggc cgccaacaag accugcccca ccaacuacau guggaacaac cacaucugcc      840

gcugccucgc ccaggaggac uucauguucu ccuccgacgc cggcgacgac uccaccgacg      900

gcuuccacga caucugcggc cccaacaagg agcucgacga ggagaccugc cagugcgucu      960

gccgcgccgg ccuccgcccc gccuccugcg gcccccacaa ggagcucgac cgcaacuccu     1020

gccagugcgu cugcaagaac aagcucuucc ccucccagug cggcgccaac cgcgaguucg     1080

acgagaacac cugccagugc gucugcaagc gcaccugccc ccgcaaccag ccccucaacc     1140

ccggcaagug cgccugcgag ugcaccgagu ccccccagaa gugccuccuc aagggcaaga     1200

aguuccacca ccagaccugc uccugcuacc gccgccccug caccaaccgc cagaaggccu     1260

gcgagcccgg cuucuccuac uccgaggagg ucugccgcug cguccccucc uacuggaagc     1320

gcccccagau guccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  4087
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt2)

<400>  4087
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uaccgcgagu gggucgucgu caacgucuuc augaugcucu      120

acguccagcu cguccagggc uccuccaacg agcacggccc cgucaagcgc uccucccagu      180

ccacccucga gcgcuccgag cagcagaucc gcgccgccuc cucccucgag gagcuccucc      240

gcaucaccca cuccgaggac uggaagcucu ggcgcugccg ccuccgccuc aaguccuuca      300

ccuccaugga cucccgcucc gccucccacc gcuccacccg cuucgccgcc accuucuacg      360

acaucgagac ccucaagguc aucgacgagg aguggcagcg cacccagugc uccccccgcg      420

agaccugcgu cgaggucgcc uccgagcucg gcaaguccac caacaccuuc uucaagcccc      480

ccugcgucaa cgucuuccgc ugcggcggcu gcugcaacga ggagucccuc aucugcauga      540

acaccuccac cuccuacauc uccaagcagc ucuucgagau cuccgucccc cucaccuccg      600

uccccgagcu cguccccguc aaggucgcca accacaccgg cugcaagugc cuccccaccg      660

ccccccgcca ccccuacucc aucauccgcc gcuccaucca gauccccgag gaggaccgcu      720

gcucccacuc caagaagcuc ugccccaucg acaugcucug ggacuccaac aagugcaagu      780

gcguccucca ggaggagaac ccccucgccg gcaccgagga ccacucccac cuccaggagc      840

ccgcccucug cggcccccac augauguucg acgaggaccg cugcgagugc gucugcaaga      900

cccccugccc caaggaccuc auccagcacc ccaagaacug cuccugcuuc gagugcaagg      960

agucccucga gaccugcugc cagaagcaca agcucuucca ccccgacacc ugcuccugcg     1020

aggaccgcug ccccuuccac acccgccccu gcgccuccgg caagaccgcc ugcgccaagc     1080

acugccgcuu ccccaaggag aagcgcgccg cccagggccc ccacucccgc aagaaccccu     1140

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  4088
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt3)

<400>  4088
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgaug agaccggcuu cgaacacucc gggcuguggg      120

ugucuguccu cgccggacuu cuguugggug cuugccaggc acaucccauc ccugacucaa      180

guccauuacu gcaauuuggc gggcagguua gacagaggua ccuauauaca gaugacgccc      240

agcaaacuga ggcgcaccuc gaaauucggg aggauggaac ggugggcggu gcugccgacc      300

agagcccgga aucccugcuu cagcugaagg cauugaaacc cgggguaaua cagauccucg      360

gagugaagac cucucgcuuc cugugucaac gaccugaugg cgcccuguac ggcucgcucc      420

auuuugaccc agaggcuugc ucauuccgug aguuacugcu ugaagauggg uauaacgucu      480

accagagcga ggcacacgga uugccccugc aucuaccugg uaauaaaagu ccacacagag      540

accccgcccc uaggggccca gcucgguuuc ucccgcugcc cgggcuuccu ccagcccugc      600

ccgaaccucc aggaauuuug gcgccccagc cgccugaugu gggcuccucu gacccccuca      660

gcaugguugg uccaucccag gggcgcucac cuaguuaugc aagcugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  4089
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt3)

<400>  4089
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc ccccucugcu ccuucuguug uucuggggcg      120

uggucuccca uucuuuccca gccaccuuag agacacagga acaagacguu gaucuggugc      180

agaaguaccu agagaaauau uacaaccuca agaaugacgg gagacaggua gagaaaaggc      240

ggaacucagg accggugguc gaaaagcuga aacagaugca agaauuuuuc ggucuuaagg      300

ugacuggcaa gcccgaugcu gagacgcuga aaguuaugaa gcagccucgc ugcggggugc      360

cagacgucgc acaguuugug uugaccgagg gaaauccccg augggaacag acacaccuca      420

cuuaucguau cgagaacuac accccugauc ugccaagagc cgacguagau caugcgauug      480

aaaaggcuuu ccaacugugg aguaauguua caccccucac cuuuacuaaa gugagcgagg      540

gccaggccga cauaaugauc uccuucguca ggggugauca ccgggacaac ucuccuuuug      600

augggccagg aggcaauuua gcacaugccu uccagccggg ccccgggauu ggaggugacg      660

cucacuuuga ugaggacgaa cgcuggacaa acaauuucag agaguauaac cugcacaggg      720

uggcagccca ugaacuuggc cacucguugg ggcugucaca uagcaccgac aucggagcuc      780

uaauguaccc uaguuauacg uuuuccggcg augugcagcu cgcccaagac gauauugacg      840

guauccaggc gauauacggg cggucucaga auccagucca acccaucgga ccucagacuc      900

caaaagcaug ugauagcaag cugaccuucg acgccauuac aacuauccgc ggcgagguua      960

uguucuuuaa ggaucgauuc uacaugagaa ccaaccccuu uuauccggaa guggagcuua     1020

auuucauuuc cguauuuugg ccucagcugc ccaacggcuu ggaggcugcc uacgaguucg     1080

cagacaggga ugaagugcgg uuuuucaaag ggaauaagua uugggcuguc cagggacaaa     1140

acgugcucca cgguuaccca aaagacaucu auucaaguuu uggcuucccu cguacaguua     1200

agcacauaga ugccgcgcug agcgaagaga acaccgggaa aacguacuuu uucguggcca     1260

auaaguauug gcgcuacgac gaauacaaaa gaucuaugga ccccggauau ccaaagauga     1320

uugcacauga uuuucccggc aucggucaca aggucgacgc uguguucaug aaagaugggu     1380

ucuuuuacuu cuuucauggc acuaggcagu auaaguucga cccuaaaaca aagcggauuu     1440

uaacccugca gaaagccaac uccugguuua auugccgaaa gaacugagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  4090
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt3)

<400>  4090
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc ccccucugcu ccuucuguug uucuggggcg      120

uggucuccca uucuuucguu uuaaccgagg ggaacccaag augggaacag acacaccuga      180

cuuacaggau cgagaauuau acgccggacc uaccccgggc cgauguggac caugcuauug      240

aaaaggcauu ucaacucugg ucaaacguaa ccccucugac auucacuaaa gugagugagg      300

gacaggccga uauaaugauc agcuuugucc gcggugacca ccgagauaau uccccauucg      360

acggccccgg gggaaaccuu gcgcaugcuu uucagccugg cccagguauu gggggagaug      420

cccacuucga cgaagaugag cguuggacca auaacuuuag agaguacaau cugcacaggg      480

uggcagccca ugaauugggc cacucucucg gccugucgca uucaacagac aucggggcuc      540

ugauguaucc cagcuacacc uucaguggag auguucagcu cgcacaagac gauauugacg      600

guauccaggc cauauauggc cggucccaga acccugugca gccaaucggg ccgcaaacuc      660

ccaaggcuug cgacucuaaa uuaacauuug augccauuac cacgauccgc ggagagguca      720

uguucuuuaa ggacagauuc uacaugagga cuaauccuuu cuauccagaa guggagcuga      780

acuuuauuag cguauucugg ccccagcuuc cuaauggcuu ggaggcggca uacgaauuug      840

ccgaucggga cgagguucgc uucuuuaaag guaacaagua cugggcugug caggggcaga      900

auguccugca cggauaucca aaggauaucu acuccucauu cggcuuuccc cgaaccguga      960

aacacauaga cgccgcacua agugaagaga acacaggcaa gacuuauuuc uuuguggcua     1020

auaaauacug gagauaugau gaauacaaga ggagcaugga cccgggguau ccuaaaauga     1080

uugcccauga uuuccccgga aucggucaca aggucgacgc gguuuuuaug aaggauggcu     1140

ucuuuuacuu cuuccauggg acccggcaau acaaauuuga cccaaagaca aaacguauuc     1200

ucacccugca gaaggccaac ucuugguuca acugucgcaa aaauugagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  4091
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt3)

<400>  4091
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaaaaaca uccugaagau ucucauggac agcuacucca      120

aagagucuaa gauacagacc gugagaaggg ucacaucagu uagucuucug gccguguauu      180

ugacuaugaa uacgagcucc uuaguacugg cuaaacccau cgaaaacacc aaugauacau      240

cuauuaagaa cguggagaag cuacggaaug caccuaacga agaaaauucg aaaaaggucg      300

aagacucaaa gaacgauaag guggagcacg uuaaaaauau cgaggaagcc aagguggagc      360

aagucgcgcc agaaguaaag agcaaaagua cucuccgcuc cgcuucuauu gccaacacca      420

auagcgagaa guacgacuuc gaguaucuga acggccuuuc cuacacagaa cugaccaauu      480

ugaucaaaaa cauaaagugg aaucagauca acgggcucuu uaacuauuca acuggaaguc      540

agaaauucuu uggugauaag aaucgagugc aggcaauuau caacgcccug caagagagcg      600

gccguacaua caccgcuaau gacaugaaag ggauugaaac guucacugag guucugagag      660

caggauuuua ucucggcuac uacaacgaug guuuaucuua ucugaaugac aggaacuucc      720

aggauaagug caucccggcc augauagcua uucagaagaa ucccaacuuu aaacuuggga      780

ccgccgugca ggacgaaguc aucacauccu ugggaaagcu gauuggcaau gcgucagcaa      840

acgccgaggu ggugaauaac ugugucccug uucuaaaaca auuccgggag aaucucaacc      900

aguacgcucc agauuaugug aagggcacug ccguaaauga acugaucaaa gggaucgagu      960

uugacuucag cggagcagcu uacgaaaagg augugaagac caugcccugg uaugguaaaa     1020

uugacccuuu uauaaacgag cuuaaggccc ugggcuugua cgggaacauc acaagugcga     1080

ccgaaugggc cucugacguc ggaauuuauu accucuccaa auucggccug uacagcacga     1140

aucgcaacga uaucgugcag ucguuagaga aggcaguuga cauguauaaa uacgguaaga     1200

uagcuuuugu ggccauggag agaauuacuu gggauuauga cgggaucgga ucuaauggca     1260

agaaagucga ucaugacaag uuccuggaug acgcugaaaa acacuaccuc ccaaagacau     1320

auaccuucga uaacggcacu uuuaucauua gggccgggga caaagugucc gaggaaaaga     1380

ucaagcggcu uuacugggca ucacgcgagg uaaaaaguca guuccaucga guugugggaa     1440

augauaaggc ccuggaaguc gguaacgcug acgacguguu gacaaugaaa auuuuuaaua     1500

gccccgagga guauaaguuc aacaccaaua uaaacggcgu cuccacggau aaugggggac     1560

uauacaucga accuagaggc accuuuuaca cauaugagag gacuccacaa cagucuauuu     1620

ucagccugga ggagcucuuu cggcacgagu acacccauua ucugcaggcg cguuaccuug     1680

uggacggucu gugggggcaa ggcccguucu augaaaagaa ccgcuugaca ugguuugaug     1740

agggaacugc agaguucuuu gccggcucaa ccagaacaag ugggguucuc cccaggaagu     1800

ccauccuggg auacuuagcu aaagacaagg uggaucaccg guauagccug aagaaaaccc     1860

uaaauucugg uuacgacgau ucagacugga uguucuacaa cuauggcuuu gccguagcac     1920

acuaccucua ugaaaaggau augccuacuu ucaucaaaau gaauaaggcc auucugaaca     1980

cggacgucaa aaguuacgau gaaauaauca agaaacuuag cgacgaugcu aacaaaaaua     2040

cagaguauca gaaccauauu caggaguugg ccgacaagua ccagggggca ggaaucccac     2100

ugguguccga cgauuaucuc aaagaccacg gcuacaagaa agcgucugaa guuuacucgg     2160

agauuagcaa ggcugccucc cugaccaaua cuucagugac cgcagaaaag agucaauauu     2220

ucaacacauu uacccuucga gguacuuaca caggggagac gucuaaaggc gaguucaagg     2280

auugggacga aaugagcaaa aagcuggaug gaaccuugga gucccucgcc aaaaauucau     2340

ggagcggcua uaagacucug acagcuuacu uuaccaacua ucgcgucaca ucugacaaua     2400

aggugcagua cgauguagug uuccaugggg uuuuaacuga caacgccgau aucuccaaua     2460

acaaagcacc cauagcuaag gucaccggac cuaguacggg ugccgugggc agaaauaucg     2520

aauuuagcgg gaaagacucu aaggaugagg acggaaaaau uguguccuau gauugggacu     2580

ucggcgacgg ugcgaccuca agggggaaga acagugucca cgccuacaaa aaggcuggca     2640

cauacaaugu uacucugaag gugaccgaug acaaaggagc aacagccacu gagagcuuua     2700

ccaucgaaau uaagaacgaa gauacgacaa ccccaaucac uaaagagaug gagcccaaug     2760

acgauauaaa ggaagcuaac ggcccgauug uggagggggu aacagucaaa ggagaccuaa     2820

acggcucgga ugacgccgau accuucuauu uugacgugaa ggaagauggu gacguuacua     2880

ucgagcuccc uuacuccggg ucuagcaauu ucaccuggcu gguguauaag gagggagacg     2940

aucagaacca cauugcauca ggcaucgaca aaaauaacag uaaggucggu acauuuaaau     3000

ccacgaaggg ccggcauuac guguucauau auaaacacga uucugcgagc aauaucuccu     3060

acucacuuaa cauuaagggg uugggaaaug aaaagcugaa agagaaggaa aacaaugaca     3120

gcagugauaa agccaccguu auccccaacu uuaauacuac aaugcagggc ucucuccugg     3180

gggacgauuc ccgcgacuau uacagcuucg aggugaagga agagggagag guaaacauug     3240

aauuagauaa aaaggacgag uucggcguca ccuggacacu gcauccagaa ucgaauauca     3300

acgauagaau aacuuacggu caaguggacg ggaauaaggu gucaaacaaa gucaaacuua     3360

ggccuggaaa auauuacuug cucguuuaua aguacucugg cagugguaau uaugagcugc     3420

gugugaacaa augaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  4092
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt3)

<400>  4092
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuuuucuccu      120

cugccuacuc aauugcuaac acaaauagug agaaauauga cuuugaauac cugaacggcu      180

ugagcuauac ugaguuaacg aaucugauaa agaacaucaa auggaaucag auuaacgggc      240

uauucaauua cuccaccgga ucucaaaagu uuuucgguga uaaaaacaga guccaggcaa      300

ucauuaaugc ccuccaggaa ucgggcagga cauauacugc gaacgacaug aaggggaucg      360

agaccuuuac agaaguucug cgggcuggau ucuaccuugg cuauuacaau gauggucugu      420

cauacuugaa cgaccgcaau uuucaggaua agugcauacc cgccaugauc gcaauucaga      480

aaaacccuaa uuucaagcuc gggaccgccg ugcaagacga gguaaucacu agccugggaa      540

aacugauugg caacgcuagu gcaaacgccg agguggucaa uaacugugug ccaguucuca      600

agcaguuucg agaaaauuua aaccaguaug cuccggauua cgugaaaggc acagccguca      660

augagcugau caaggggaua gaauuugacu uuuccggagc ggcauaugag aaggauguga      720

aaaccaugcc cugguacggu aagauugacc cuuucaucaa cgagcuuaaa gccuugggcc      780

uguaugggaa uauuacgucu gcuacugaau gggccagcga uguaggaauc uacuaucuau      840

ccaaguucgg ccucuacuca accaaccgua augacaucgu ucaaagucug gagaaagcag      900

uggauaugua caaguauggu aaaauugcuu uugucgccau ggaaagaaua acaugggacu      960

acgacgggau cggaagcaac ggcaagaagg uggaucacga caaauuccuu gaugacgcgg     1020

agaagcauua ucugccaaaa acuuacaccu uugauaaugg cacauucauu aucagggccg     1080

gggacaaggu gucugaagag aaaauaaagc gguuguauug ggcaucccgc gaggucaagu     1140

cacaguuuca cagaguugug ggaaacgaua aagcucucga aguagguaau gccgacgaug     1200

ugcugaccau gaagauuuuc aacagccccg aggaauacaa auuuaauacg aacaucaacg     1260

gcgucaguac ugacaauggg ggauuauaua ucgagccuag gggcacauuc uacaccuacg     1320

aacggacucc acagcagucu auuuucuccc uggaggagcu guuccgccau gaauauacac     1380

acuaccuuca agcucgauau cugguggaug guuugugggg gcagggcccc uuuuacgaga     1440

agaacagacu aaccugguuc gacgaaggaa cggccgaguu uuucgcaggc agcaccagga     1500

caucgggggu ucugccucgg aaaucuaucc ucggauaucu ggccaaggac aagguggauc     1560

aucguuacuc ccuuaaaaag acucucaauu cagguuauga cgauagugac uggauguucu     1620

acaacuacgg cuuugcuguc gcgcacuauu uguacgaaaa agauaugcca accuucauua     1680

agaugaauaa agcaauacuc aacacagacg uaaagagcua ugaugagauc auuaagaaac     1740

uguccgacga ugccaauaag aacacugagu accagaauca cauccaagaa uuagcugaca     1800

aauaucaggg ggccggaauc ccgcuggugu cugaugacua ccuaaaggau cauggcuaua     1860

aaaaggcaag cgagguuuac ucagaaauua guaaagccgc uucccucacc aacacaagcg     1920

ugaccgccga gaagucucag uacuuuaaua cuuucacgcu gcgcgguaca uauaccgggg     1980

agacuucaaa gggcgaauuu aaagacuggg acgagaugag uaagaaacuu gauggaaccu     2040

uggaaagccu ggcaaagaac uccuggucug gcuacaaaac acucaccgcg uauuucacua     2100

auuacagagu cacaucggac aacaaggugc aguaugaugu cguguuucac gggguucuga     2160

cggacaaugc ugauauaagc aacaacaagg cccccaucgc aaaagugacc ggaccuucca     2220

cuggugccgu aggcaggaau auugaguucu cagggaagga caguaaagau gaagacggaa     2280

agaucgucuc uuacgauugg gacuuuggcg auggugcuac aagccggggg aaaaacuccg     2340

ugcaugccua uaagaaggca ggcaccuaca auguuacacu uaaagugacu gacgauaagg     2400

gagcuaccgc cacggaguca uucaccauug agaucaaaaa cgaagacaca acuaccccaa     2460

uaacaaagga gauggaaccc aaugacgaua ucaaagaggc gaacggcccu auugucgaag     2520

gggugacugu aaagggagac cugaauggca gcgaugacgc cgauaccuuu uacuucgacg     2580

ugaaggagga uggugacguu acgaucgagu ugccauauuc uggguccagu aacuuuacau     2640

ggcucgucua caaagaagga gaugaccaaa aucacauugc uagcggcauc gauaagaaca     2700

auucuaaagu ggguaccuuc aaguccacua aaggccgaca cuauguguuc auauacaagc     2760

augacucagc aaguaacauu agcuauucgc ugaauaucaa aggguuagga aacgagaagc     2820

ugaaggaaaa agagaauaac gacuccucug auaaggccac agucauuccc aacuuuaaua     2880

ccacuaugca gggcagccua cucggggacg auucacgcga cuacuauagu uucgaaguua     2940

aagaggaggg agaagugaac aucgagcugg auaagaaaga cgaauuuggc gugaccugga     3000

cacuucaccc ggaguccaau auaaacgaua gaaucacgua cggucaggua gacgggaaua     3060

aggucucuaa caaggugaaa uugaggccug gaaaguacua ucugcucguu uacaaauaua     3120

gcggcuccgg uaauuacgag cugcggguga acaagugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  4093
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt3)

<400>  4093
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuuuucuccu      120

cugccuacuc aaugaaaaag aacauucuga aaauauugau ggacaguuau agcaaggagu      180

ccaaaaucca gacagucaga aggguuacuu cugugucguu acuggcugua uaccuaacga      240

ugaauaccuc aagccucgug cuggcaaagc ccauugaaaa cacaaaugau acuagcauca      300

agaacgucga gaaacuucgg aaugccccua acgaagaaaa uuccaagaaa guggaagacu      360

cuaagaacga uaaaguugag cacgugaaga auauugagga agcgaagguc gagcaagugg      420

cuccagaagu aaaaagcaag uccacccugc gcucagccag ucgacguaga aggaaacgga      480

ucgcaaacac aaauagcgag aaguaugacu uugaguacuu gaacggccuc ucuuauaccg      540

aacugacuaa ucugaucaaa aacauaaagu ggaaucagau uaacggacuc uucaacuacu      600

ccacaggauc acagaaauuu uucggugaua agaaucgcgu ucaggccauc auuaacgcuu      660

uacaagagag cggcagaacc uauacggcaa augacaugaa ggggaucgaa acuuuuaccg      720

aggugcugag ggccggauuc uaccuuggcu acuauaacga ugguuugagu uaccugaaug      780

accggaacuu ucaggauaaa ugcauaccgg cuaugauugc cauccagaag aaucccaacu      840

ucaaacuagg gacagcgguc caggacgaag ugauuacuuc ucucggaaag cugaucggca      900

augcauccgc caacgcugag guggucaaua acuguguucc ugugcuuaaa caauuucgcg      960

agaaucugaa ccaguaugcc ccagauuacg uaaagggcac cgcagugaau gaauugauca     1020

aggggauuga guucgacuuu agcggagcug ccuaugaaaa agaugucaag acaaugcccu     1080

gguacgguaa aauagacccu uucaucaacg agcucaaggc gcugggcuua uaugggaaca     1140

uuaccucggc cacggaaugg gcaucugacg ugggaaucua cuaccugucc aaauucggcc     1200

ucuauucaac uaaucgaaac gauauaguuc agagucuuga gaaggcugug gacauguaca     1260

aguaugguaa aauugccuuu gucgcuaugg agagaaucac augggauuac gacgggaucg     1320

gaagcaaugg caagaaagug gaucaugaca aguuccugga ugacgccgaa aaacacuauu     1380

ugccaaagac cuacacuuuu gauaacggca cauucauuau cagggcaggg gacaagguau     1440

ccgaggagaa aauuaagcgg cuauauuggg ccucucguga gguuaaaagc caguuucauc     1500

gcguggucgg aaaugauaag gcucuggaag uggguaacgc ggacgacguc cucaccauga     1560

aaauauucaa uucacccgag gaguacaagu uuaacacgaa uaucaacggc gugaguaccg     1620

auaauggggg acuguacauu gaaccuagag gcacauucua uacuuacgag aggaccccac     1680

aacaguccau cuuuagccuu gaggaacugu uccggcacga guauacacau uacuugcagg     1740

cacgauaucu cguugacggu cugugggggc aaggcccguu uuacgagaaa aaccgcuuaa     1800

cuugguucga ugaaggaacc gccgaauuuu ucgcuggcuc uacaagaacc ucaggggugc     1860

ugcccaggaa gaguauccua ggauaucucg ccaaggacaa aguagaucac cgguacagcc     1920

ugaagaaaac ucuuaauucc gguuacgacg auucugacug gauguucuau aacuacggcu     1980

uugcagucgc ccacuauuug uacgagaagg auaugccuac guucauuaaa augaauaagg     2040

cuauacugaa cacagacgug aagucguaug augaaaucau uaaaaagcuc agcgacgaug     2100

ccaacaaaaa uaccgaguac cagaaccaua uccaggagcu ggcagacaag uaucaggggg     2160

cggggauucc acuuguuucc gacgauuacc ugaaagacca cggcuacaag aaggcuucag     2220

aaguguauag ugagaucucu aaagccgcaa guuugacuaa uaccuccguc acagccgaaa     2280

agucacaaua cuuuaacacc uucacucucc gcgguacaua uacgggggag accagcaaag     2340

gcgaauuuaa ggauugggac gagaugucua aaaagcugga uggaacuuua gagucccugg     2400

cuaagaauag uuggagcggc uacaaaacac uaaccgccua uuucacaaac uacagaguga     2460

cuucugacaa uaagguacag uaugaugugg uuuuucaugg gguccucacc gacaacgcag     2520

auauauccaa uaacaaagcu cccaucgcca aggugacggg accuucaacc ggugcggugg     2580

gcaggaauau ugaguucagu gggaaagaca gcaaggauga agacggaaaa aucgucucgu     2640

acgauuggga cuuuggcgac ggugccacau cccgugggaa gaacucuguu cacgcuuaca     2700

agaaagcagg cacuuauaau gugacccuga aggugacaga ugacaaagga gccacugcua     2760

ccgagagcuu cacgauugaa aucaagaacg aagauacaac cacuccaaua acaaaagaga     2820

uggagcccaa ugacgauauu aaggaagcca acggcccgau cguagagggg gucaccguga     2880

agggagaccu uaacggcuca gaugacgcag auacuuuuua cuucgacguu aaagaagaug     2940

gugacgugac cauugaguug ccuuauagug gguccucuaa uuuuacaugg cuggucuaca     3000

aggagggaga cgaucagaac cacaucgcga gcggcauaga caaaaauaac uccaaggugg     3060

guacguucaa aucaaccaag ggccggcauu auguuuucau cuacaagcac gauagcgcca     3120

guaauauuuc uuauucccuc aacaucaaag ggcugggaaa ugaaaaguua aaagagaagg     3180

aaaacaauga cagcucggau aaagcuacug ugauucccaa cuuuaauaca accaugcagg     3240

gcucacugcu uggggacgau ucucgagacu acuacaguuu cgagguaaag gaagagggag     3300

aggucaacau cgaauuggau aagaaagacg aguuuggcgu gacauggacu cuccauccag     3360

aauccaauau aaacgauaga auuaccuaug gucaagugga cgggaauaag gucagcaaca     3420

aaguuaagcu gaggccugga aaauacuauc uacuggugua caaguauucu ggcagcggua     3480

auuacgagcu ccgcguaaac aagugaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  4094
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt3)

<400>  4094
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuga agaucauucu caauagaggc aaaaccauga      120

agaggaaaug ccuuagcaag cggcugaugu uggccauaac aauggcuacu aucuuuacgg      180

ugaacuccac cuuacccauu uacgcagccg ucgacaaaaa uaacgcgaca gcugccguuc      240

agaaugaguc uaagcgcuau acugugucau accugaagac ccuaaacuau uacgaucucg      300

uagaccugcu ugugaaaaca gaaaucgaga aucugccuga uuuguuccaa uauaguagcg      360

acgcaaagga auuuuacggg aacaaaaccc gaauguccuu cauuauggau gagaucggac      420

guagagcccc acaguauacu gaaauagacc acaaggguau cccgacacuc gucgaggugg      480

uuagggcugg cuuuuaccug ggguuccaua auaaagagcu gaacgaaauu aauaagcggu      540

cuuuuaagga gcgcgugauc cccucgauuc ucgcaaucca gaaaaacccu aauuucaagu      600

uaggaaccga aguccaggau aaaauagugu cagccacggg ccugcuugcu gguaacgaga      660

cugccccacc cgagguaguu aauaacuuua ccccuauuuu gcaagacugu aucaagaaca      720

uugauagaua cgcgcuggac gaucuaaaaa gcaaggcacu cuucaaugug cuggccgcuc      780

caacauauga caucacugaa uaccuuaggg ccaccaaaga gaagcccgaa aacacaccuu      840

gguaugggaa gaucgaugga uuuauuaaug agcugaaaaa guuggcacuc uacggcaaaa      900

uaaacgacaa uaacaguugg aucauugaca auggcaucua ucacauagcu ccacugggga      960

aguuacauuc caacaauaaa auuggaaucg aaacccugac ggaggucaug aagguguacc     1020

cguaucucuc uaugcagcac cuucagagcg ccgaucagau caagcggcau uacgacucca     1080

aagaugcgga ggguaacaag auuccccugg acaaauucaa gaaagaaggc aaggagaagu     1140

acugcccuaa aacuuauaca uuugaugacg ggaaggugau cauuaaagcc ggagcacgcg     1200

ucgaagagga aaagguuaaa cgauuguacu gggcuucaaa ggaggugaau agucaauucu     1260

ucagaguaua uggcauagau aagccacuag aggaagguaa ccccgacgau auccugacca     1320

uggugauuua caauagcccu gaggaauaua aacucaacuc uguccuguac ggguaugaca     1380

cuaauaacgg aggcauguac aucgagccag aaggcacauu uuucaccuac gagagggagg     1440

cccaggaauc cacguauacc cuugaggaac uguuucggca cgaguacaca cacuauuugc     1500

aggggcguua cgcugugccc ggacaguggg gucgcacuaa gcucuaugau aacgacagac     1560

ugaccuggua cgaggaaggc ggggccgagu uauucgcagg aucaacaagg acuagcggca     1620

uccugccgcg gaaaaguauu guuucuaaua uacauaacac cacacgaaau aaccgcuaua     1680

agcuauccga caccgugcac agcaaauacg gugccucguu ugaguucuac aauuaugcuu     1740

guauguuuau ggauuacaug uauaacaagg acauggggau ccucaauaaa cugaacgauc     1800

uugcgaagaa uaacgacguc gauggcuacg acaauuauau uagagauuug ucuuccaacu     1860

acgcacugaa ugacaaguau caagaucaua ugcaggaaag gaucgacaac uacgaaaauc     1920

ucacugugcc uuucguagcc gaugacuacc ugguucggca cgcuuauaaa aaccccaacg     1980

agauuuacuc agagaucagu gaaguggcca aacuuaagga ugcaaagagc gaggucaaaa     2040

agucccagua uuuuucuacg uucacacugc gcggaagcua caccggcggg gccucaaagg     2100

gaaaauugga agaccaaaag gcuaugaaua aauuuauaga cgauagucuc aagaaacugg     2160

acacuuauuc cuggagcggu uacaagaccu uaacagccua uuucaccaac uacaaggugg     2220

auucuucaaa uagagucacu uacgacgugg uuuuucacgg cuaucugcca aacgaggggg     2280

auaguaaaaa uagccuaccu uacggaaaga ucaacggcac auauaaaggu acggaaaagg     2340

agaaaauuaa guucuccucu gaggggucgu ucgaccccga uggcaagauc gugagcuacg     2400

aaugggacuu uggagauggc aauaaaucca acgaggaaaa uccagagcau ucauaugaca     2460

agguagggac cuacacuguc aaacucaagg ugacagauga caaaggagaa aguucuguua     2520

gcaccacaac ugcagagauu aaggaucugu ccgagaacaa acuucccgug aucuauaugc     2580

acgucccuaa gucaggugcg uugaaucaga aggugguauu cuacggcaaa gggaccuacg     2640

acccagacgg aagcauagcu ggcuaucagu gggauuuugg ugacgggucu gauuucucca     2700

gugaacagaa cccgagccau guguacacga agaaaggcga guauaccguu acacugaggg     2760

ucauggacuc uuccggacaa augucagaaa agacuaugaa aauuaagauc accgaucccg     2820

uguacccuau uggcacagag aaggagccaa auaacaguaa agaaacugcc agcgggccca     2880

ucgugccugg aauaccaguc ucgggcacca ucgagaauac guccgaccag gauuauuuuu     2940

acuucgacgu uauuacaccc ggugaaguga agaucgauau uaacaaacuc ggguauggag     3000

gcgcaaccug ggugguauac gacgagaaca auaacgccgu cucuuacgcu acugaugacg     3060

gucagaaucu gagcggcaag uuuaaagccg acaagccggg gcguuauuac auccacuuau     3120

auauguucaa cggaucauac augccuuauc ggauaaauau ugaaggcagu guggggcgau     3180

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  4095
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt3)

<400>  4095
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagagaaaau gccugagcaa gaggcucaug cuugccauca      120

ccauggcuac aauuuucacu gugaacucca cgcugcccau auacgcagcc gucgacaaaa      180

auaacgcgac cgcugccguu cagaaugagu cuaagcggua uacaguguca uacuugaaaa      240

cuuuaaacua uuacgaucug guagaccuac ucgugaagac cgaaaucgag aaucugccug      300

aucuuuuuca auauaguagc gacgcaaagg aguucuacgg caacaaaaca cgcauguccu      360

uuauuaugga ugaaaucggg cgacgugccc cacaguauac cgaaauugac cacaagggaa      420

ucccgacucu ggucgaggug guuagagcug guuucuacuu gggcuuucau aauaaagagc      480

ucaacgaaau aaauaagagg ucuuucaaag agcgggugau ccccucgauu cuggcaaucc      540

agaagaaccc uaauuuuaag cuggggacag aaguccagga uaaaauugug ucagccaccg      600

gacucuuagc uggcaacgag acggccccac ccgagguagu uaauaacuuc acuccuaucc      660

ugcaagacug uauaaagaau auugaucgcu acgcgcuuga cgauuugaaa agcaaggcac      720

uguuuaacgu gcuagccgcu ccaaccuaug acaucacaga auaccucaga gccacuaaag      780

agaagcccga aaacaccccu ugguauggua aaauugaugg guucaucaau gagcugaaga      840

agcuggcacu guacggaaaa aucaacgaca auaacaguug gauuauagac aauggcaucu      900

aucacauugc uccauugggc aagcuccauu ccaacaauaa aaucgggaua gaaacacuga      960

ccgaggucau gaagguguac ccguauuuau cuaugcagca ccuucagagc gccgaucaga     1020

uuaaaaggca uuacgacucc aaggaugcgg agggaaacaa gaucccccuc gacaaauuua     1080

agaaagaagg uaaggagaaa uacugcccua agacguauac uuucgaugac ggcaagguga     1140

ucauuaaagc cggggcacgg gucgaagagg aaaagguuaa acgccuuuac ugggcuucaa     1200

aggaggugaa uagucaauuu uuccgaguau auggaaucga uaaaccacug gaggaaggca     1260

accccgacga uauuuugaca auggugauau acaauagccc ugaggaauau aagcuaaacu     1320

cuguccugua cgguuaugac accaauaacg ggggaaugua caucgagcca gaaggcacuu     1380

ucuuuacaua cgagagagag gcccaggaau ccaccuauac gcucgaggaa cuguucaggc     1440

acgaguacac ccacuaucuu cagggccggu acgcugugcc cgggcagugg ggacguacaa     1500

agcuguauga uaaugaccgc uugacuuggu acgaggaagg uggcgccgag cucuuugcag     1560

ggucaaccag aacaagcggc auucugccga ggaaaaguau cguuucuaac auccauaaca     1620

cuacccggaa uaaccgauau aaguuauccg acacagugca cagcaaauac ggagccucgu     1680

ucgaauuuua caauuaugcu uguauguuca uggauuacau guauaacaag gacaugggua     1740

uucugaauaa acuaaacgau cucgcgaaga auaacgacgu cgauggguac gacaauuaua     1800

uacgcgaucu gucuuccaac uacgcacuua augacaaaua ucaagaucau augcaggaga     1860

gaaucgacaa cuacgaaaau uugaccgugc cuuuuguagc cgaugacuac cugguuaggc     1920

acgcuuauaa gaaccccaau gagauuuacu cagagaucag ugaaguggcc aagcucaaag     1980

augcaaagag cgaggucaaa aagucccagu auuucucuac uuuuacgcug cggggcagcu     2040

acacaggagg cgccucaaaa gggaaacuug aagaccaaaa ggcuaugaac aaguucauug     2100

acgauagucu gaagaaauug gacaccuauu ccuggagcgg auacaagacu cucaccgccu     2160

auuuuacaaa cuacaaagug gauucuucaa aucgcgucac cuacgacgug guuuuccacg     2220

guuaucugcc aaacgagggc gauaguaaga auagcuuacc uuacgggaag aucaacggaa     2280

cuuauaaagg cacagaaaag gagaaaauaa aguuuuccuc ugaggguucg uucgaccccg     2340

augggaaaau cgugagcuac gaaugggacu ucggcgaugg aaauaagucc aacgaggaaa     2400

auccagagca uucauaugac aagguaggca cguacaccgu caaacugaag gugacugaug     2460

acaaagggga aaguucuguu agcacaacca cagcagagau uaaggaucua uccgagaaca     2520

aacuccccgu gaucuauaug cacgucccua agucaggagc gcugaaucag aaagugguau     2580

uuuacgguaa gggcacuuac gacccagacg ggagcauugc uggauaucag ugggauuucg     2640

gcgacgguuc ugauuuuucc agugaacaga acccgagcca uguguacacc aagaaagggg     2700

aguauacggu uacccuuaga gucauggacu cuuccggcca aaugucagaa aagacaauga     2760

aaaucaagau aacugauccc guguacccua uuggaaccga gaaagagcca aauaacagua     2820

aggaaacagc cagcggcccc aucgugccug ggauuccagu cucgggaacu aucgagaaua     2880

ccuccgacca ggauuauuuc uacuuugacg uuauaacgcc cggcgaagug aagaucgaua     2940

uuaacaaauu ggguuauggg ggagcaacau gggugguaua cgacgagaau aacaacgccg     3000

ucucuuacgc uaccgaugac ggccagaauc ugagcgguaa guucaaagcc gacaagccgg     3060

gcagguauua cauccaccuc uauauguuua acgggucaua caugccuuau cguauuaaua     3120

ucgaaggaag ugugggccgg ugaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  4096
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt3)

<400>  4096
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuuuucuccu      120

cugccuacuc aguccagaac gagaguaaaa gauauacagu uagcuaccug aagacuuuga      180

auuauuacga cuuaguggau cugcuaguaa aaacggaaau ugagaaccuc cccgaccugu      240

uucaauauuc cucugaugcu aaggaguucu acggcaauaa aaccaggaug ucguuuauaa      300

uggacgaaau cggccggcgc gcaccucagu auacagaaau ugaucacaag ggaaucccaa      360

cucuugugga ggucgugcga gccgguuucu accugggcuu ucauaacaag gaguugaaug      420

aaauuaacaa acguucauuc aaggagagag uuaucccgag cauacucgcg auccagaaaa      480

aucccaacuu uaagcugggg accgaagugc aggacaaaau ugucagugcu acaggacugc      540

ucgccggcaa ugagaccgca ccuccagagg ugguaaacaa uuucacuccc aucuuacaag      600

auugcauuaa gaacaucgac agguacgccc uggaugaccu uaaguccaag gcuuuguuua      660

auguucuggc agccccuaca uaugauauaa ccgaauaccu acgggcuacg aaggagaaac      720

cagaaaacac ucccugguau gguaagauug acggguucau caaugagcuc aaaaagcugg      780

cccuuuacgg aaaaauuaac gauaacaauu cuuggaucau cgacaacggc auuuaucaca      840

uagcgccucu gggcaaguug cauagcaaua acaagaucgg gauugaaacc cucacagagg      900

ugaugaaagu cuacccauau cuguccaugc agcacuuaca gucagcagac cagaucaagc      960

gccauuacga uaguaaagac gccgagggaa auaagauacc gcuggauaaa uuuaagaagg     1020

aagguaaaga gaaguacugu cccaaaacuu auaccuucga cgauggcaag gugauuauca     1080

aagcuggggc cagaguggaa gaggaaaagg ucaagaggcu cuacugggca agcaaagagg     1140

uuaacucuca auucuuucgg guguauggaa ucgacaagcc ucuugaggaa ggcaauccag     1200

augacauucu gacaauggua aucuacaacu cccccgagga auauaaacua aauucagugu     1260

uguacgguua ugauaccaac aaugggggaa uguacauuga gccugaaggc acguucuuua     1320

cuuacgagcg cgaggcucag gaaagcacau auacccugga ggaacucuuc cgacacgagu     1380

acacucacua ucugcagggc agauacgccg ucccagggca guggggaagg acaaaacuuu     1440

augacaacga ucggcugacc ugguacgagg aagguggcgc ggaguuguuu gccgggagua     1500

cgcguaccuc uggaauacuc ccccgcaaau ccaucgugag caauauucau aacacaacua     1560

gaaauaacag guauaagcug ucggacaccg uucacucuaa guacggcgca uccuucgaau     1620

uuuacaacua ugcuugcaug uucauggacu acauguauaa uaaagauaug gguaucuuaa     1680

acaagcugaa ugaccuagcc aaaaacaaug auguggacgg guacgauaac uauauccggg     1740

accucucaag uaauuacgcu cugaacgaua aguaucaaga ccauaugcag gagcgaauug     1800

auaauuacga aaaccuuaca gucccguuug uggccgacga uuacuuggua cgccacgcau     1860

auaaaaaucc uaacgagaua uacagcgaga ucuccgaagu ugccaagcug aaagacgcua     1920

agucugaggu gaagaaaagc caguauuucu caacuuuuac ccucagaggc aguuacacag     1980

gaggcgcguc caaggggaaa cuggaagauc aaaaggcaau gaauaaauuc auugacgaca     2040

gccuuaagaa gcuggauacc uauucuuggu caggauacaa aacuuugacg gccuauuuua     2100

caaacuacaa ggucgacagu agcaauaggg ugaccuacga ugucguguuc cacgguuauc     2160

uccccaacga gggcgacucc aaaaacucuc ugccauacgg gaagaucaau ggaacuuaua     2220

aaggcaccga aaaggagaag auuaaauucu cgagcgaggg uuccuuugau ccugacggga     2280

agaucguuuc auacgaaugg gauuucggcg acggaaacaa aaguaaugag gaaaaccccg     2340

agcauucuua ugauaaggug ggcacauaca ccguaaaauu aaaggucacu gacgauaagg     2400

gggaaagcuc cgugucaaca acgaccgcug agauaaaaga ccugagcgag aauaagcuac     2460

caguuaucua uaugcacgug cccaaaucug gagcccucaa ccagaagguc guguuuuacg     2520

guaaaggcac uuacgauccu gacgggucca uugcaggaua ucagugggac uucggcgaug     2580

guagugacuu uagcucugaa cagaauccau cccauguaua cacaaagaaa ggggaguaua     2640

ccgugacacu gcggguuaug gauucaagug gccaaaugag cgaaaagacu augaagauca     2700

aaauuaccga cccggucuac cccaucggaa cggagaagga gccuaacaau ucgaaagaaa     2760

ccgccuccgg cccaauagug cccgggauuc cugugucugg aacaaucgag aacacuagcg     2820

aucaggacua uuucuacuuu gaugucauua ccccaggcga aguuaagauc gacauaaaua     2880

aacuugguua ugggggagcu acaugggugg uguacgauga gaacaauaac gccguaucau     2940

acgcaacuga cgauggccag aauuugagug guaaguucaa ggcggacaaa cccggccgcu     3000

auuacaucca ccuguauaug uuuaacgggu ccuacaugcc guauagaauu aacaucgaag     3060

gaucugucgg gaggugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4097
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt3)

<400>  4097
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuuuucuccu      120

cugccuacuc aaugaaaaga aagugccuga guaaaagguu gauguuagcu auuacaaugg      180

caacuauauu uacggucaac agcacccugc ccaucuaugc cgcgguugac aagaauaacg      240

cuacagccgc acggcgccga cguaaaagag ugcagaauga guccaagagg uacacuguau      300

cuuaucuaaa gacccucaac uacuaugauc ugguggaccu ucuggucaaa acagaaauug      360

agaauuugcc ugaucucuuc caauacucgu cagacgccaa ggaauuuuau ggcaacaaaa      420

cccggaugag cuucaucaug gaugagauug ggcgcagagc uccacaguac acugaaaucg      480

accacaaggg aauaccgaca cugguggagg uugugagggc agguuuuuac cugggcuucc      540

auaauaaaga gcucaacgaa aucaauaagc ggaguuuuaa ggagcgcguc auucccucca      600

ucuuagccau ucagaaaaac ccuaauuuca agcuggggac cgaagugcag gauaaaaucg      660

uaucugcuac gggacuuuug gccggcaacg agacugcgcc acccgagguu gugaauaacu      720

uuaccccuau acugcaagac uguauuaaga auaucgaucg auaugcacua gacgaucuca      780

aaagcaaggc ccuguucaac guccuugcug ccccaacaua cgacauuacu gaauaucuga      840

gagcaaccaa agagaagccc gaaaacacac cuugguacgg uaagaucgau ggguuuauca      900

augaguugaa aaagcucgcu cuguauggaa aaauuaacga caauaacucc uggauaaucg      960

acaauggcau uuaccacauc gccccauuag gcaagcugca uucaaacaau aaaauaggga     1020

uugaaacccu cacggaggug augaaggugu auccguaccu uaguaugcag caucugcaga     1080

gcgcggauca gaucaagagg cacuacgacu cuaaagaugc cgagggaaac aagauccccu     1140

uggacaaauu caagaaagaa gguaaggaga aguauugccc uaaaacuuac acauucgaug     1200

acggcaaggu cauuaucaaa gcaggggcuc ggguugaaga ggaaaaggug aaacgucuau     1260

auugggccuc caaggaggua aauucacaau uuuuccgcgu guacggaauu gauaagccac     1320

uggaggaagg caaccccgac gauauacuca ccauggucau cuauaauagc ccugaggaau     1380

acaaacugaa cagugugcuu uaugguuacg acacuaauaa cgggggaaug uacauugagc     1440

cagaaggcac auuuuucacc uaugagagag aggcucagga aucuacguac acccuggagg     1500

aauuguuuag gcacgaguau acacacuacc uccagggccg guaugccguu cccgggcagu     1560

ggggacgaac uaagcuguac gauaaugacc gcuuaaccug guaugaggaa gguggcgcag     1620

agcuguucgc cggguccaca agaacuagcg gaauccuacc gaggaaaucg aucgugucua     1680

acauucauaa caccacacgg aauaaccgcu acaagcucuc cgacaccguc cacucaaaau     1740

acggcgcuag uuuugaguuc uauaauuacg cguguauguu uauggauuau auguacaaca     1800

aggacauggg uauacugaau aaacuuaacg auuuggcaaa gaauaacgac guggaugggu     1860

augacaauua caucagagau cugagcucca acuaugcccu caaugacaag uaccaagauc     1920

auaugcagga aaggauugac aacuacgaaa aucugacugu accuuucguu gcugaugacu     1980

aucuugugcg ucacgccuac aaaaacccca augagaucua uucugagauu agcgaagucg     2040

caaagcugaa agaugccaag ucagagguga aaaagaguca guacuuuucc acguucacau     2100

ugcggggcag cuauaccgga ggcgcuucua aggggaaacu cgaagaccaa aaggccauga     2160

acaaauuuau cgacgauuca cugaagaaau uagacacuua caguuggagc ggauauaaga     2220

cccugacagc auacuucacc aacuacaagg ucgauuccuc uaaucgagug acuuaugacg     2280

uuguguucca cgguuaccua ccaaacgagg gcgauucgaa aaauagccuc ccuuauggga     2340

agauaaacgg aacauacaaa ggcacggaaa aggagaaaau caaguuuucc ucagagggua     2400

guuucgaccc cgaugggaag auuguaucuu augaauggga cuuuggcgau ggaaauaaaa     2460

gcaacgagga aaauccagag cauuccuacg acaaggucgg caccuauacu gugaaacuga     2520

agguuacaga ugacaaaggg gaaucaagcg ugucuaccac aacugcggag aucaaggauc     2580

uuuccgagaa caaauugccc gucauuuaca ugcacgugcc uaagagugga gcucugaauc     2640

agaagguagu guucuacggu aaaggcaccu augacccaga cgggagcauc gccggauacc     2700

agugggauuu uggcgacggu ucugauuucu ccucagaaca gaacccgagu cauguuuaua     2760

cgaagaaagg ggaguacacc gucacacuca gagugaugga cagcucgggc caaauguccg     2820

aaaagacuau gaaaauaaag auuaccgauc ccguguaucc uaucggaaca gagaaggagc     2880

caaauaacuc uaaagaaacu gcaagcggcc ccauuguccc ugggauccca guuucaggaa     2940

ccauagagaa uacgagugac caggauuacu uuuauuucga cgugaucaca cccggcgaag     3000

ugaagauuga uaucaacaaa cuggguuacg ggggagccac cuggguaguc uacgacgaga     3060

auaacaacgc uguguccuau gccacugaug acggccagaa uuuaucuggu aaguuuaaag     3120

cagacaagcc gggcagguac uauauucacc uguacauguu caacgggagc uauaugccuu     3180

accgcaucaa uauagaagga uccguuggcc ggugaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  4098
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt3)

<400>  4098
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccuu ggggcugcau      120

uugccaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc agcuaugagg      180

uguugacacc uuuaaagugg uaccagucca uaagaccacc cuauccuucu uacggcuaug      240

aaccaauggg aggguggcug caccaucaaa ucauucccgu ccuaucacag cagcacccuc      300

caacucauac gcuccagccg caccaccaua uccccguugu gccugcgcaa cagccaguaa      360

uuccccagca gccuaugaug ccagugcccg gccaacacag uaugaccccg auccagcauc      420

accagccuaa ucugcccccu ccagcucagc aacccuacca gccacagccc guccaaccuc      480

agccacacca gccgaugcag ccccaaccuc cagugcaucc caugcagccu cuuccacccc      540

agccgccucu gccacccaug uuuccuaugc agcccuugcc accuaugcuc cccgaccuga      600

cacuggaggc cuggccaagc acugauaaaa ccaagaggga agagguugac ugaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  4099
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt3)

<400>  4099
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccaguc cauuagacca cccuauccuu      180

cuuacggaua ugaaccaaug gguggcuggu gaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  4100
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt3)

<400>  4100
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccaguc cauuagacca cccccuaugc      180

ugccagacuu gacauuagaa gccuggcccu cuacugauaa aacgaagagg gaggaagucg      240

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  4101
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt3)

<400>  4101
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cuucugagcg      120

gcgcauuggc cuuaacacag acuugggcga ugccucugcc accgcacccc gggcauccug      180

gauacaucaa cuucuccuau gagguucuaa cgccacucaa gugguaccaa ucuauuaggc      240

ccccuuaucc aucauacggu uaugaaccca ugggcgggug gugaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  4102
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt3)

<400>  4102
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cuucugagcg      120

gcgcauuggc cuuaacacag acuugggcga ugccucugcc accgcacccc gggcauccug      180

gauacaucaa cuucuccuau gagguucuaa cgccacucaa gugguaccaa ucuauuaggc      240

ccccuccaau gcugcccgac cuuacccugg aggcuuggcc uucaacagau aaaacuaagc      300

gggaagaagu ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  4103
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt3)

<400>  4103
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccucgug ggggcugcau      120

uugccaugcc ccuuccucca cacccgggac aucccgguua cauuaacuuc agcuaugagg      180

uccugacacc uuugaagugg uaccagucca ugauaagacc acccuauucu ucauacggcu      240

augaaccuau gggagggugg uuacaccauc aaaucauucc aguugugagu cagcagcacc      300

cccugacuca uacgcuacag agccaccacc auaucccugu agugccagcg caacagccga      360

ggguccggca gcaggcucuc augcccgugc cuggccaaca guccaugacc ccaacacagc      420

accaucagcc caaucugccu cuuccagccc aacagcccuu ucagccgcaa ccuguucagc      480

cccagccaca ccagccuaug caaccccagc cacccgugca gccuaugcag ccacuguugc      540

cgcaaccccc ucucccaccc auguucccuc ugcgcccacu gcccccgauu cucccugacu      600

uacaccugga ggcauggcca gccacugaua aaaccaagca ggaagagguc gacugaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  4104
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt3)

<400>  4104
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccaguc caugauuaga ccacccuauu      180

cuucauacgg auaugaaccu auggguggcu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4105
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt3)

<400>  4105
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccaguc caugauuaga ccacccccua      180

uacugccaga cuugcacuua gaagccuggc ccgcuacaga uaaaacuaag caagaggaag      240

ucgacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4106
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt3)

<400>  4106
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cuucugagcg      120

gcgcauuggc cuuaacacag acuugggcga ugccucugcc accgcacccc gggcauccug      180

gauacaucaa cuucuccuau gagguucuaa cgccacucaa gugguaccaa ucuaugauua      240

ggcccccuua uucaaguuac gguuaugaac caaugggcgg guggugagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4107
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt3)

<400>  4107
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cuucugagcg      120

gcgcauuggc cuuaacacag acuugggcga ugccucugcc accgcacccc gggcauccug      180

gauacaucaa cuucuccuau gagguucuaa cgccacucaa gugguaccaa ucuaugauua      240

ggcccccucc aauacugccc gaccuucacc uggaggcuug gccugccacc gauaaaacaa      300

agcaggaaga aguggacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4108
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt3)

<400>  4108
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccuu ggggcugcau      120

uuagcaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc uccuaugagg      180

uguugacacc uuuaaagugg uaccagaaua ugauaagaca cccauauacu ucuuacggcu      240

augaacccau gggagggugg cugcaucacc aaaucauucc ugucguuuca cagcagacgc      300

cacagaguca ugcccuacaa ccccaccacc auaucccuau ggugccagcg cagcagccgg      360

gcauucccca gcaaccuaug augccacucc ccggucagca cagcaugacc ccuacacagc      420

aucaccagcc aaaccugccc cuuccggcuc aacagccuuu ucagccccaa ccaguacagc      480

cucagcccca ccagccacug caaccccagu ccccuaugca uccaauccag ccguugcucc      540

cccagccucc acugcccccu auguucucua ugcaaucgcu gcucccagac uuaccccugg      600

aggccuggcc ggcaacugau aaaaccaaga gggaagaggu ggacugagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4109
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt3)

<400>  4109
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccagaa uaugauuaga cacccauaua      180

cauccuacgg auaugaaccc auggguggcu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4110
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt3)

<400>  4110
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccagaa uaugauuaga cacccauccc      180

uguugcccga cuuaccucug gaagccuggc cagcuacaga uaaaacuaag agggaggaag      240

ucgacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4111
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt3)

<400>  4111
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cuucugagcg      120

gcgcauuggc cuuaacacag acuugggcga ugccucugcc accgcacccc gggcauccug      180

gauacaucaa cuucuccuau gagguucuaa cgccacucaa gugguaccaa aauaugauua      240

ggcaccccua uaccucuuac gguuaugaac cuaugggcgg guggugagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4112
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt3)

<400>  4112
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cuucugagcg      120

gcgcauuggc cuuaacacag acuugggcga ugccucugcc accgcacccc gggcauccug      180

gauacaucaa cuucuccuau gagguucuaa cgccacucaa gugguaccaa aauaugauua      240

ggcaccccuc ucugcuuccu gaccugccau uggaggcuug gcccgccacc gauaaaacaa      300

agcgggaaga aguggacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4113
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt3)

<400>  4113
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccuu ggggcugcau      120

uuagcaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc uccuauauaa      180

gacacccuua cacaucuuau ggcuacgagc caaugggagg gugguugcau caccagauca      240

uucccguggu cucacaacag acuccucaga gucaugccuu acagccacac caccauaucc      300

ccaugguucc ugcgcaacag ccaggcauuc cgcagcagcc caugaugccu cugccagguc      360

aacacagcau gacgcccacc cagcaucacc agccuaaucu accacucccc gcucagcaac      420

cguuucagcc ucagcccgug caaccacagc cucaccagcc ccugcagcca caauccccca      480

ugcauccuau ccagccacuu cugccgcagc ccccuuugcc acccauguuc ucuaugcagu      540

cgcuccugcc ugaccugcca cucgaagccu ggcccgcaac agauaagacu aaaagggagg      600

aaguagacug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  4114
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt3)

<400>  4114
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuuugc cugccugcuc ggggcuagcc      120

uugcaaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc uccuaugagg      180

uguugacacc uuuaaagugg uaccagaaua ugauaagaca cccauauacu ucuuacggcu      240

augaacccau gggagggugg cugcaucacc aaaucauucc ugucguuuca cagcagacgc      300

cacagaguca ugcccuacaa ccccaccacc auaucccuau ggugccagcg cagcagccgg      360

gcauucccca gcaaccuaug augccacucc ccggucagca cagcaugacc ccuacacagc      420

aucaccagcc aaaccugccc cuuccggcuc aacagccuuu ucagccccaa ccaguacagc      480

cucagcccca ccagccacug caaccccagu ccccuaugca uccaauccag ccguugcucc      540

cccagccucc acugcccccu auguucucua ugcaaucgcu gcucccagac uuaccccugg      600

aggccuggcc ggcaacugau aaaaccaaga gggaagaggu ggacugagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4115
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt3)

<400>  4115
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccuu ggggcugcau      120

uuagcaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc uccuaugagg      180

uguugacacc uuuaaagugg uaccagaaua ugauaagaca cccaucucug cuacccgacc      240

ucccucugga agccuggcca gcgacugaua aaacgaagag ggaggaaguc gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  4116
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt3)

<400>  4116
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccuu ggggcugcau      120

uuagcaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc uccuaugagg      180

acuuguacuu agaagccaua agaaucgaua ggacagcguu ugugcugacu ccucuaaagu      240

gguaucagaa uaugauucgg cacccauaca cgucuuaugg cuacgagccc augggagggu      300

ggcuccauca ccaaaucauu ccugucguuu cacagcagac cccacagagu caugcucugc      360

aaccccacca ccauaucccu auggugccag cccagcagcc gggcauaccc cagcaaccua      420

ugaugccacu ucccggucag cacagcauga caccuacuca gcaucaccag ccaaaccugc      480

ccuugccggc acaacagccu uuccagcccc aaccaguaca gccucagccc caccagccac      540

uccaacccca guccccuaug cauccaaucc agccgcugcu gccccagccu ccauuacccc      600

cuauguuuuc uaugcaaucg cuccugccag accuucccuu ggaagccugg ccggcuaccg      660

auaaaacaaa gcgcgaggaa guggacugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  4117
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt3)

<400>  4117
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccuu ggggcugcau      120

uuagcaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc uccuaugagg      180

uguugacacc uuuaaagugg uaccagaaua ugauaagaca cccaacuccc caaucucaug      240

cccugcagcc ucaccaucac aucccaaugg uccccgcgca gcagccuggc auuccacaac      300

agccgaugau gccccuaccu gggcagcacu caaugacgcc aacccagcau caccaaccca      360

accucccucu gccagcucag cagcccuuuc agccgcaacc uguucagccc cagccacauc      420

aaccucuuca gccccagagu ccaaugcacc ccauccagcc ucuguugcca caaccgcccc      480

ucccuccaau guucagcaug cagucccugc ugcccgaccu cccuuuagaa gccuggccag      540

caacagauaa aacuaagagg gaggaagugg acugaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  4118
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt3)

<400>  4118
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccagaa uaugauuaga cacccauaua      180

cauccuacgg auaugaaccc auggguggcu ggcugcauca ccaaauaauc ccugucguuu      240

cucagcagac uccacaguca caugccuugc aaccccacca ccauauuccu auggugccag      300

cucagcagcc ggggaucccc cagcaaccua ugaugccauu acccggacag cacaguauga      360

cgccuaccca gcaucaccag ccaaaccugc cccuaccggc acaacagccu uuucagcccc      420

aaccaguaca gccucagccc caccagccac uccaacccca gagcccuaug cauccaauuc      480

agccgcugcu uccccagccu ccacugcccc cuauguucuc caugcaaucu uugcucccag      540

accugccccu ggaggccugg ccggcgacag auaaaacuaa gagggaagag guggacugag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  4119
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt3)

<400>  4119
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg ccagacugcc ucuccuucug ggguuguuac      120

ugcuaccaag gccgggacgg ccccucgacc uggcugauua caccuaugac cuugcagagg      180

aagaugacag cgagccucug aacuacaagg auccaugcaa agccgcggcu uucuugggug      240

acaucgcccu cgaugaagag gaccugcgcg cauuucaggu ccaacaggcc guugaucugc      300

gacgucacac agcuagaaag uccucuauua aagcagccgu gcccggcaau acuucaacgc      360

cuaguuguca gagcaccaac gggcagccac aaaggggagc uugcggccgg uggcgcggua      420

gauccagguc ucggcgcgcc gcgacaucgc gacccgaaag aguauggccu gacgggguga      480

uaccauucgu caucggaggc aauuuuacug gcucacagag ggcaguguuc cggcaggcca      540

ugcgucauug ggagaagcac accuguguua cauuucucga gcgcaccgau gaagacagcu      600

auauuguguu cacuuacaga ccgugcgggu guugcaguua ugucggaagg cgggguggcg      660

ggccccaggc uaucuccauu ggaaagaacu gugauaaguu uggcaucgug guacaugagu      720

uaggucacgu ugugggguuc uggcaugaac acacacgacc ugaccgcgac agacacgucu      780

cuauagugag ggagaauauc caaccaggac aggaguacaa cuuucugaag auggaacccc      840

aggaggugga aagccuuggc gagaccuaug auuucgacuc cauuaugcau uacgcccgga      900

auacguuuuc acgcggcauc uucuuggaua cuauuguccc uaaauacgaa guuaacgggg      960

ugaagccacc caucggacag agaaccaggc ugaguaaagg ugacauagca caagcucgua     1020

agcuauauaa augcccggcc uguggcgaga cacuccagga uagcacuggg aauuuuucuu     1080

ccccugagua ccccaacgga uauucagcgc acaugcauug cguauggcgg auuagcguga     1140

ccccaggcga aaagaucauu cugaauuuca caagucuuga ccuguaccga ucuagauugu     1200

guugguauga uuacgucgag gugagggacg guuucuggcg caaggccccu cuccggggga     1260

gauuuugcgg cuccaaacug cccgaaccaa ucguuagcac cgauucgagg uuaugggugg     1320

aguuccgauc uuccucaaac ugggucggaa agggcuuuuu cgcaguguau gaagcuaucu     1380

gcgggggaga cguuaaaaag gauuacgguc acauucagag ucccaauuac ccugacgacu     1440

aucgcccaag caaaguaugu auauggcgga uccaaguguc cgagggcuuu cacgucgggc     1500

ugacguucca gucuuuugag auugaacguc augauagcug cgccuacgac uaucucgagg     1560

ugagagaugg acacucagaa aguuccacuc uuaucggcag guacuguggu uaugagaagc     1620

cggacgauau aaaaagcaca ucuucacgcc ugugguugaa guucgucagu gacgggagca     1680

uuaacaaggc uggcuuugcc gugaauuucu uuaaagaagu ugaugagugc ucccggccca     1740

acagaggagg cugugagcag aggugccuaa acacccuggg gucuuacaag uguucgugcg     1800

acccuggaua ugaacucgca ccagauaaac gacgcuguga ggccgcuugc gguggcuucc     1860

ugacuaaacu uaaugggagc aucacauccc ccggauggcc uaaagaauac ccacccaaca     1920

agaauuguau cuggcagcug guggcgccga cccaauaccg gauuucauug caguuugacu     1980

ucuucgagac ggagggcaac gauguaugca aguaugacuu ugucgaagug agaagugguc     2040

ucaccgcaga uucuaaacug caugggaagu ucugcggcag cgagaaaccu gaaguuauca     2100

caucccagua caauaacaug aggguggagu uuaagucaga caauacuguc agcaaaaagg     2160

gauucaaggc ccacuuuuuc ucugacaaag augaauguuc caaggacaac ggcgggugcc     2220

agcaagauug ugugaauacc uuuggaaguu augagugcca gugucguagc ggcuucguau     2280

uacaugacaa caaacacgau ugcaaggagg cugguuguga ccacaaagug acaucuacuu     2340

ccgggaccau uacaucacca aauuggcccg auaaguaccc uaguaagaaa gaaugcaccu     2400

gggccauaag cucgacuccc ggacaucgcg uuaagcugac guuuauggag auggacaucg     2460

aaucccagcc agagugugca uaugaucacc uagaagucuu cgacggccgg gaugccaaag     2520

cuccugugcu cgguagauuu ugcggcucua agaaacccga gccagugcug gccacaggga     2580

gcaggauguu ccuucgauuu uacucagaca acagugucca gcggaaggga uuccaagcau     2640

cccaugcgac cgaguguggc gggcagguuc gcgcugaugu gaaaacuaag gacuuguauu     2700

cucacgccca guucggagac aauaacuacc cgggcggugu ggauugcgaa uggguaauug     2760

ucgcagagga aggguacgga guggagcugg uuuuucagac cuucgaagug gaggaggaaa     2820

cagacugcgg cuaugauuac auggagcucu uugacgguua ugauagcacc gccccuagac     2880

ugggcaggua cugugggucc ggacccccag aagaggucua uucagcuggc gacagcgugc     2940

uuguuaaguu ccacagugau gacacuauca cgaaaaaggg guuucaucug cgguacacau     3000

cuaccaaauu ccaagauacu uugcacuccc gaaagugagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  4120
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt3)

<400>  4120
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggca ccagaugccu gcucgcuuug cuguugcccc      120

aggucuuacu gggaggggca gccggucuag uuccugagcu cggcaggcgg aaguucgcgg      180

cugccagcuc cgggcgccca ucuucacaac cgagugacga agugcugagc gaguuugaac      240

uucgacuguu guccauguuc ggacucaaac agcgucccac accuucuaga gaugcaguag      300

ugccacccua caugcuggac cuguauaggc ggcacucggg ccagccuggu ucaccagccc      360

ccgaucaucg ccucgagaga gcugcaagca gggccaacac uguccggagu uuucaccaug      420

aagaguccuu agaggaacug ccugagacgu cugggaagac cacacgccga uucuuuuuca      480

aucuuagcuc caucccaacu gaagaguuua uuaccucagc ugagcuucag guguucagag      540

aacaaaugca ggacgcccug ggaaacaaua guagcuuuca ccauaggaua aacaucuacg      600

agauuaucaa accggcgaca gcaaauucua aguuccccgu uacccggcua cucgauacuc      660

gucuggugaa ccagaaugcc ucccgcuggg aaucauuuga cgucaccccu gcugugauga      720

gauggacagc ccagggccac gcaaaccacg gcuucguagu ugagguggcu caucuugaag      780

agaaacaagg ggucagcaag aggcacgugc ggauuagucg aucucugcau caggaugagc      840

acuccuggag ccagauccgc ccauugcucg ugacguuugg acacgacggu aagggccauc      900

cccugcacaa aagagaaaag aggcaggcca aacauaagca acggaaacgc uuaaagucgu      960

cuuguaagag acacccucug uaugucgauu ucuccgacgu uggguggaau gauuggauag     1020

uggcgccacc cggauaccau gccuucuauu gccacggcga guguccguuu ccucucgcag     1080

accaccuuaa cucaacuaau caugcuaucg uacagacccu ggugaacagu gucaauagca     1140

aaauucccaa ggccugcugu gugccaacag aauuguccgc uaucucuaug cuauaccugg     1200

augagaacga aaaaguugug cucaagaauu aucaggacau ggucguggag gguugcgggu     1260

guaggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  4121
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt3)

<400>  4121
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auccccggca acagaaugcu gauggugguc cuccuuugcc      120

agguucuguu agggggagcc agccacgcuu ccuugauucc ugagaccggu aagaaaaagg      180

uggcagaaau acaaggccau gccgggggaa ggcggucugg ccagucacac gagcugcuac      240

gcgacuucga agcgacacuc cugcagaugu uuggucuucg acguagacca cagccgagua      300

aaagcgcugu aauccccgau uacaugaggg accuguaucg guugcaaucc ggggaggaag      360

aggaggaaca gauucauucu acuggacucg aguacccuga acgcccagcc ucgagagcaa      420

auacggugag gucauuccac caugaggagc accuggaaaa cauccccggc accagcgaga      480

auagugccuu ucgguuccug uuuaaccucu ccucuauucc ugaaaaugag gucaucagcu      540

ccgcugaauu acgccuguuc cgagaacagg uggaucaggg cccagacugg gagagagggu      600

uucacaggau aaacaucuau gagguuauga agcccccugc agaggugguc ccaggacauc      660

uuauuacacg guugcuggau acucgucuag ugcaccauaa uguaacccgc ugggaaacau      720

ucgacguuuc accggccgug cucagaugga ccagggagaa acaacccaac uacggucugg      780

cuaucgaagu cacucaccuu caccagacac ggacccauca gggccagcac gugcgaauua      840

gucgcagccu gccucaaggg ucuggaaauu gggcccaguu gagaccacuc cuggugacgu      900

uuggccauga ugguaggggg cacgcguuaa cucggcgcag aagggcaaag cguuccccca      960

agcaucacuc acagcgggcc cgaaagaaaa acaaaaauug uagaaggcac agccuguaug     1020

ucgacuucag ugauguugga uggaacgacu ggaucguggc uccuccaggc uaccaagccu     1080

uuuauugcca uggcgauugu cccuucccgc ucgcagacca ccuuaauucu accaaccaug     1140

cuauaguaca gacacugguc aauuccguga acagcucgau uccuaaggcc ugcugugugc     1200

ccacugaguu gucugcgauc uccaugcuau accuggauga guacgacaaa guugugcuca     1260

agaacuauca ggaaaugguc guggaggggu gcggaugucg cugaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  4122
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt3)

<400>  4122
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggccuag ggagaagggc ccaguggcuc ugcugguggu      120

ggggacuucu guguagcugc ugugguccuc caccguugcg gcccccuuua ccagcugcag      180

ccgcggcugc cgcaggcggg caacugcuag gagacggcgg uucccccggg cgcaccgagc      240

agccuccacc cucuccucag ucaaguagcg gauuccucua ccgacgucug aagacacagg      300

agaaaagaga aaugcaaaag gaaauccuuu ccgugcuggg cuugccacac aggccgcggc      360

cccuccaugg ccugcagcag ccucagccac ccgcccugcg ccaacaggag gaacagcagc      420

aacagcagca acucccuaga ggggagccac ccccgggaag guuaaaaucu gcuccucugu      480

uuaugcuuga uuuguauaac gcacugucgg ccgacaauga ugaggacggu gcuucagaag      540

gcgagcggca gcagagcugg ccccacgaag ccgcgaguuc cucucagcgc cgacaaccac      600

cucccggggc agcccaucca cuaaacagaa agagccuccu ggcucccgga uccggcucag      660

guggggccag uccucuuacu agcgcacagg auucugcuuu ccugaaugac gccgauaugg      720

ucauguccuu uguuaacuug guggaguacg acaaagaguu cucaccaagg cagcggcacc      780

auaaggaauu uaaguucaau cucagccaga uuccggaggg agaaguagug acggcggccg      840

aguuucguau auauaaagau ugcgucaugg gcaguuucaa gaaccaaacc uuucugaucu      900

cuauuuacca gguguuacag gaacaccagc accgcgacuc cgaucuguuc cuccuugaca      960

caagaguugu gugggcaagc gaggagggcu ggcuggaauu ugauaucacu gcuaccucga     1020

auuugugggu cgugacaccc caacauaaca uggggcuaca gcugucugua guuaccaggg     1080

acggagugca cguccauccu cgggccgcug gucucguggg ccgagacggg ccauaugaua     1140

aacagcccuu caugguggcc uuuuucaagg ucuccgaggu ucacgugcgc acuacaagau     1200

cagcaaguag caggcggcgc cagcaaucca gaaauagguc uacccagagc caggacguag     1260

cccguguguc aagugcuucc gauuacaaca gcucugaacu gaaaacggcg ugucggaagc     1320

acgagcuuua ugucucauuc caagaccugg gauggcagga uuggauuauc gcaccuaagg     1380

gcuacgccgc uaauuacugc gacggugaau guaguuuucc auugaacgcc cauaugaaug     1440

caacuaacca cgccauagug cagacccucg uucaucugau gaaucccgag uaugugccga     1500

aaccuugcug ugcuccaaca aaguuaaacg ccaucagcgu ccuguacuuc gaugacaacu     1560

ccaaugugau ucugaaaaag uaucgaaaca ugguaguuag agcaugcggg ugucacugag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  4123
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt3)

<400>  4123
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugagaa gccugagggc cgcugcaccc cauuccuucg      120

ucgcccucug ggcgccucuu uuucuguugc ggucugcuuu agccgacuuc ucacuggaua      180

acgagguuca caguagcuuu auccaucgcc gacuacguuc ccaggaaaga agggagaugc      240

aacgggaaau ucucucuaua cugggccuuc cacaccgccc gagaccccau cugcagggga      300

agcacaauuc ggcaccuaug uucauguugg accucuacaa cgccauggcu guggaggaag      360

gagguggccc agggggacag ggcuuuucau aucccuacaa agcaguauuc agcacccagg      420

guccuccacu ggccagucug caagauuccc acuuucucac agacgcugau auggugaugu      480

cuuucgucaa uuuaguggag caugacaagg aguuuuucca ccccagguau caucaccggg      540

aauuucgcuu cgaucugagc aaaaucccug agggggaagc cguuacugcg gcagaguuuc      600

gaauuuacaa ggacuauauc agagagaggu ucgauaacga aacguuccgg auuuccgugu      660

accagguccu ucaggagcac uugggacgug aaucagaccu guuucuacuc gauagucgca      720

cccugugggc cagcgaggaa ggcuggcuug uguucgacau cacagcuacu ucuaaucauu      780

ggguaguuaa cccaagacac aaucugggcu ugcagcucuc cguggagacc cuggaugggc      840

aaucaauaaa cccgaaauua gccggacuga ucgguaggca uggcccccag aauaagcagc      900

cuuuuauggu cgcauucuuu aaggcuacag aggugcacuu ccggagcauu cgaaguaccg      960

ggucuaaaca gcgcucccaa aacagaagca agacucccaa aaaucaggaa gcccucagga     1020

uggcgaacgu ggccgaaaau ucgucuuccg accagcggca agcaugcaag aaacaugagc     1080

uuuaugucuc auuucgcgac cugggauggc aggauuggau cauugcucca gagggcuacg     1140

ccgcuuacua uugugaaggu gagugcgccu ucccuuugaa caguuacaug aaugcaacaa     1200

accacgccau cguucagacc cuagugcacu uuauaaaccc agagacggua cccaagccgu     1260

guugcgcucc uacucagcug aaugcgauua gcgugcucua uuucgacgau uccucuaacg     1320

ucauccugaa gaaauacaga aauauggugg uuagggcaug ugggugccau ugaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  4124
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt3)

<400>  4124
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggccagcg cugcacugcu cugccuucug uugaccgccg      120

cggcuuucuc uccccagggc uuagcccaac cuguggggau caacacaucc acuacguguu      180

gcuacagauu uauuaauaaa aagauaccaa aacagaggcu ggagucauau cggcgcacca      240

caaguagcca cuguccgcga gaagcaguca ucuucaagac uaaacuagac aaggagauuu      300

gcgccgaucc cacccagaag uggguucagg acuuuaugaa acaucucgau aagaaaacac      360

aaaccccuaa gcugugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  4125
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt3)

<400>  4125
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucaccc uuaucauucu guugcccgug gucagcaagu      120

ucuccuuugu uucuuuauca gccccucagc acuggaguug cccagagggc acacuggcug      180

ggaacggaaa uagcacuugu guggguccgg cacccuuccu aauauuuucc cauggcaacu      240

cuaucuucag aauugacacg gaagggacca auuacgagca acucguagug gacgccggag      300

ucucggugau cauggacuuu cacuauaacg aaaagaggau uuacuggguu gaucuggagc      360

ggcagcuucu gcagcgcgug uucuugaaug gcucacgaca ggaacguguc ugcaacaucg      420

agaagaaugu gagcgguaug gcgauaaacu ggaucaauga ggaaguaauu uggaguaacc      480

aacaggaggg gaucauuaca guuacugaca ugaaaggaaa uaacucccau auccuccugu      540

cugcucugaa guauccugcc aauguggcag ucgauccagu ggaaagauuu auauucugga      600

gcuccgaggu ggccggcuca cucuacaggg cugacuuaga uggcgucggg guuaaagcac      660

ugcuugagac cagugaaaag auuacagccg ugagcuugga cguacuggau aagcggcuau      720

uuuggaucca guauaaccgc gagggaucua auucccucau uuguucaugc gacuacgaug      780

guggcagcgu gcacaucagu aaacauccca cccagcacaa ccuguucgcu augucucuuu      840

uuggggacag aaucuucuau uccacuugga agaugaaaac aauuuggaua gccaacaagc      900

acaccggaaa agauaugguc aggaucaauc ugcauagcuc guuugugccu uugggcgaac      960

ucaagguugu gcacccacug gcgcaaccca aggcagagga cgacacgugg gaaccugagc     1020

agaaauuaug uaagcugcgg aaagguaacu gcucauccac ugucuguggg caggaucucc     1080

agucacaucu uugcaugugu gccgagggau acgcucugag ucgcgaccga aaguacugcg     1140

aagaugugaa ugagugugcc uucuggaacc acggcugcac cuugggcugc aaaaauacac     1200

cagggagcua uuacuguacu ugcccgguag gauucguucu acugcccgac gguaagagau     1260

gucaccaacu cguguccugc ccuaggaacg ucucugaaug uagccaugau ugcgugcuga     1320

ccucagaggg cccacuuugu uuuugccccg aagggagugu ccuggagcgg gacggaaaaa     1380

cauguuccgg cugcagcucu ccugauaaug guggguguuc acaguugugc gugccacuca     1440

gucccguuag cugggagugc gacuguuucc cgggcuauga ucugcaguua gacgaaaagu     1500

ccugcgcagc uucuggaccu caacccuuuc ugcuauucgc caacucgcag gauauucguc     1560

acaugcauuu ugacggcacc gacuacggga cgcuccugag ccagcagaug ggaauggugu     1620

augcgcuuga ucacgaccca guagagaaua agaucuacuu cgcccauacu gcauugaaau     1680

ggauagaacg cgcuaacaug gaugguuccc aaagagagag gcugauugaa gagggcgucg     1740

acgugccuga ggggcucgcc guugauugga ucggacggcg auuuuauugg acagaccgcg     1800

gcaagucacu gaucgguaga agugaucuua augggaaaag gucuaagauu aucaccaaag     1860

aaaacauuag ccagccccgg ggcauagcug ugcacccaau ggccaagcgc cuguucugga     1920

cugacacagg aaucaauccc agaauugagu ccucuagcuu gcagggccuc gggaggcugg     1980

ucaucgcauc uuccgauuua aucuggccua guggaauuac cauagacuuu cugacggaua     2040

agcuauacug gugugacgcc aaacagagcg ugaucgaaau ggcuaaccuc gaugguucua     2100

agcgucggcg acugacccaa aaugacguag gccacccauu cgcgguggca guuuuugagg     2160

acuacgucug guucuccgau ugggccaugc cgucagugau gagagugaac aaaaggacag     2220

ggaaggaccg cguccggcuu cagggaagua uguugaaacc cagcucgcug guuguggugc     2280

auccucucgc uaagccaggc gccgaucccu gccuguauca gaacgguggg ugugagcaca     2340

uuugcaagaa aagauuaggc acugcauggu guuccugcag ggaaggauuu augaaggccu     2400

cugacggcaa aaccugucug gcucuugaug ggcaucaguu gcucgccgga ggcgagguag     2460

accugaagaa ucaagucaca ccucuagaua uccugagcaa aacucgcgug ucagaagaca     2520

acauuaccga gagucagcac augcucguug cagaaaucau gguguccgau caggacgauu     2580

gcgcgccagu cgguuguucu auguacgcuc gaugcauaag cgagggggag gacgccacau     2640

gccagugucu gaagggauuc gcaggcgaug guaaacuuug cuccgacauc gacgaaugug     2700

agaugggcgu gcccguuugc ccgccugccu caagcaaaug uauuaauacc gaagggggau     2760

augugugccg guguagugag ggcuaccaag gggauggaau ccacugcuug gacauugaug     2820

aaugucagcu gggcgagcau ucuugcggug agaacgcuuc cuguacuaau acggaagggg     2880

gauauacaug caugugcgcc ggccguuuaa gcgagccagg ucucaucugu cccgacucga     2940

ccccuccccc acaccugaga gaagaugacc aucacuacuc aguaaggaac ucugauagug     3000

agugcccucu uucccaugac ggcuauuguc ugcacgaugg ggucugcaug uacauagaag     3060

cauuggacaa guacgcuugu aauugcgugg ugggauauau uggcgagcgc ugucaguacc     3120

gggaucucaa auggugggag cugagacacg ccgggcaugg acaacagcag aaggucaucg     3180

uuguggcggu augcgugguc gugcuaguua ugcugcuccu gcuuagcuug uggggcgccc     3240

acuauuacag gacucagaaa cuguuaucua agaaccccaa aaauccauau gaagagagcu     3300

cccgagacgu gcgcucacgg agaccggcug acaccgaaga ugguaugagu agcuguccuc     3360

aacccugguu cgucgugauu aaggagcauc aggaccucaa gaacggggga cagccaguug     3420

caggcgagga uggucaggcc gcugacggcu cuaugcaacc cacauccugg aggcaggaac     3480

cucagcugug cgggauggga accgagcagg gcuguuggau cccaguguca agugauaaag     3540

ggagcugccc ccaagucaug gaacguuccu uucacaugcc uucuuacgga acucagacac     3600

uugagggcgg uguagaaaag ccgcauucgc ugcuaagcgc caauccacuc uggcagcaac     3660

gcgcacugga ucccccucac cagauggagu ugacgcagug aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  4126
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt3)

<400>  4126
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggca gaaggaugga gaugcugugc gcugggcggg      120

ugcccgcacu ccuucugugu uugggauucc acuuacugca ggccguccua agcacaacug      180

uuaucccuuc cugcauucca ggugaaucuu cagacaacug uacggcgcuc gugcaaaccg      240

aggauaaucc gcgcguagcu caggugagua uaacaaagug cagcuccgac augaacggcu      300

acugucugca ugggcagugc aucuaucuug ucgauauguc ucagaauuac ugucgaugcg      360

aagugggaua uacuggcguu cguugugagc acuuuuuccu gaccgugcau caacccuugu      420

cgaaagaaua cgucgcccuc acagugauuc ugaucauucu guuucucauc accguaguug      480

guucaacuua uuacuucugc agaugguaua ggaaccgcaa gagcaaagag ccuaagaaag      540

aguacgaacg ggugacaagu ggggacccag aguuacccca ggucugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  4127
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt3)

<400>  4127
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgagggcg aaaucaccac auucacugcu cugacggaga      120

aguuuaaccu ucccccuggg aauuacaaaa agccaaaacu ccuguauugc agcaacggag      180

gucacuucuu gagaauuuua ccggacggca ccguggaugg gacaagggac cgguccgauc      240

agcauauaca acugcagcua ucugcagaau cagucggaga gguuuacauc aagaguacug      300

aaaccggcca guaucucgcc auggacacag auggucugcu uuacgggagc cagaccccca      360

augaggagug ucuguuuuug gaacgccucg aggaaaacca cuauaauacu uacauuucca      420

aaaagcaugc ggagaagaac ugguucgugg gacugaaaaa gaauggcucu ugcaaacgag      480

gcccucguac acacuauggg caaaaggcua uccuguuucu cccauuaccc guaucgucag      540

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  4128
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt3)

<400>  4128
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggcgucg ggggagguga cguugaggau gugaccccca      120

gaccuggcgg gugccagauc agcggaaggg gcgcccgggg uuguaacggg auuccaggag      180

cugcagccug ggaagcggcu cugccgcgcc gacgucccag aaggcacccu uccguaaauc      240

cacggucucg cgccgcaggc ucacccagaa caaggggccg gcgcacugag gaacgaccua      300

gugggagcag acucggagac aggggucggg gccgugcccu uccaggggga cgccugggcg      360

guagagggag gggacgggcu cccgagcgag ugggcggccg cgggagagga agggguacgg      420

cagccccucg ggcugcccca gcggcacgcg gcuccagacc ggggcccgcc ggaaccaugg      480

cugccggcuc uauaacaacu uugccugcau uaccagaaga uggugggucg ggcgcuuuuc      540

ccccuggaca uuucaaggac ccaaaaaggc uguacugcaa gaacggcggg uucuuucuac      600

guauccaccc cgauggacgg gucgacggug ugcgagagaa aucagauccg cauauuaagc      660

uccaacugca ggccgaggaa agaggcguug ugagcaucaa aggggucugu gcgaauaggu      720

aucuugccau gaaggaggac ggacgccugu uggcaaguaa gugcgugacc gaugaauguu      780

ucuuuuucga gcggcucgag uccaacaauu acaacacaua uagaucuagg aaauacacca      840

gcugguaugu agcucugaag cgcacuggcc aguacaaacu ggguuccaag acagggccug      900

gccagaaagc cauucucuuu uuacccaugu cagcuaagag uugaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  4129
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt3)

<400>  4129
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uccugaccug gauucucccc acacuucugu      120

acagaagcug cuuccauaua aucuguuugg ugggcacuau uuccuuagcc ugcaacgaca      180

ugacgccuga gcagauggcu accaauguca acuguucuuc accagaaagg cacacacgga      240

guuaugauua cauggaggga ggagacaucc gcguucgacg ucuguuuugc agaacucaau      300

gguaucuaag gauugauaaa cgggguaagg ugaaaggcac ccaggaaaug aagaauaacu      360

acaauaucau ggagauacgc acaguagcag uggggaucgu cgccauuaaa ggaguggaaa      420

gcgaguucua ucucgcgaug aacaaggagg gcaagcugua cgcuaaaaag gaauguaaug      480

aggacugcaa cuuuaaagaa cuuauccugg agaaucauua uaacaccuac gccuccgcaa      540

aguggacuca caaugguggg gagauguucg uugccuugaa ccagaaaggg auuccgguga      600

gaggcaagaa gaccaaaaag gaacagaaaa cagcucauuu ucuccccaug gcaaucacgu      660

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  4130
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt3)

<400>  4130
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugcucc ccagcguggu ccuuaaacug uucuuggccg      120

cuguuuuauc cgcacuggug accggcgagu cucuagaaag acucaggcgg gggcuggccg      180

cgggaacauc aaacccugac ccaccgacug uaaguacgga ucagcuucug cccuugggug      240

gcgggcgcga ccgaaaggug cgugaucucc aagaggcuga ccuggaucug cucagaguca      300

ccuuaagcuc caaaccucag gcccuggcaa caccaaauaa ggaggaacac ggaaaaagga      360

agaagaaagg caagggucuu gggaaaaagc gggaccccug cuugcgcaaa uacaaggauu      420

uuuguaucca uggagaaugc aaguauguga aagagcugag agccccuucu uguauuugcc      480

acccaggcua ccauggcgag aggugucacg ggcuaucgcu ccccguugaa aaccggcugu      540

auacuuacga ccauaccaca auacuugcug uggucgcagu gguacuguca agcguuugcu      600

ugcucgugau cgucggacug uuaauguucc gcuaucaccg aagagguggc uacgaugugg      660

agaaugaaga gaaggugaaa cuggggauga ccaacaguca cugaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  4131
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt3)

<400>  4131
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccuucug uugcagcacg      120

ucuuacugca ucuacuccug cuuccuaucg cuauuccaua cgcagagggc caaagaaaaa      180

ggcggaacac aauacacgag uucaagaaaa gcgccaagac uacgcugauc aaaauugacc      240

cggcguugaa gaucaagacc aaaaagguua auacagcuga ucagugcgcc aaccgcugua      300

cucgaaauaa agggcucccc uuuaccugca aggcauucgu guuugacaaa gcccguaagc      360

agugucugug guucccuuuu aacuccaugu cuucaggagu aaagaaagag uucggucaug      420

aauuugaucu guaugagaau aaggacuaca uuagaaacug caucauaggc aaagggagga      480

guuauaaggg aacagugagc aucaccaaau ccggcauuaa gugucagcca uggucuucga      540

ugauccccca cgaacauuca uuccucccua gcaguuaccg ggguaaagau uuacaagaga      600

auuauugccg caacccaaga ggggaggaag gaggccccug guguuuuacu uccaauccug      660

aggucaggua cgaagugugc gacauuccac aguguucuga gguugagugc augacaugua      720

acggcgaaag cuaucggggg cugauggauc acaccgaguc cggaaagauc ugccagcgcu      780

gggaccacca gacgccgcau cgacacaagu uccuucccga aagauacccu gauaaagguu      840

uugacgauaa uuacugcagg aacccagacg gccaaccccg gccuuggugu uauacuuugg      900

auccacauac ccguugggaa uacugcgcua uaaagacaug ugcagacaau acuaugaacg      960

acaccgaugu gccccuggaa acaaccgagu gcauucaggg gcagggagag ggcuaucgcg     1020

guacggucaa uacuaucugg aacgggauuc cgugucagag augggacuca caauacccuc     1080

acgaacacga uaugacaccc gagaacuuca aaugcaagga ccuaagggaa aauuauuguc     1140

ggaacccaga uggaagugag agcccuuggu gcuuuaccac ugaccccaau auccgagugg     1200

gcuacuguuc ucagauccca aacugcgaua ugucccaugg ccaggacugu uaucgcggga     1260

augguaaaaa cuacauggga aaucucucac aaacaagaag cggccugacc ugcaguaugu     1320

gggauaagaa cauggaagac cuucacaggc auauuuucug ggagcccgau gccucuaagc     1380

ugaaugagaa cuacugccgg aauccugacg acgaugcuca cgggccaugg uguuauacgg     1440

gaaacccguu gauacccugg gacuacugcc cuaucucccg cugugaaggc gauaccacac     1500

caacuauugu aaaucucgac caucccguua ucagcugcgc caaaaccaag cagcugagag     1560

uggucaacgg uauaccuaca aggacuaaua uuggguggau ggugucguua cguuaucgga     1620

acaaacacau cuguggcgga ucucugauca aggaguccug ggugcucacc gcgcgacagu     1680

gcuucccauc aagagaucuu aaagacuacg aagcauggcu gggcauucac gauguccaug     1740

ggaggggaga cgagaagugu aagcagguuu ugaacgugag ucagcuagua uauggucccg     1800

aaggcagcga ucuggugcuc augaaacugg cccgcccggc uguccuugac gauuuugugu     1860

ccacaaucga ccugccuaau uacgggugca ccauuccaga gaagacuucu uguagcguuu     1920

auggaugggg cuacacgggu uugauaaacu acgaugggcu ccugcgggug gcccacuuau     1980

auaucauggg caaugagaaa ugcucacaac aucacagagg aaaggucaca cugaacgaaa     2040

gugagauuug ugcaggcgcu gagaaaaucg gguccggacc cugcgaaggu gacuacggcg     2100

ggccucuagu gugcgagcag cacaagauga ggaugguacu cggaguuauc gugcccggcc     2160

gcgguugugc cauuccaaau cgaccuggga uauucguccg gguggcguau uacgccaagu     2220

ggauccauaa aauuauccug accuauaagg ucccccagag cugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  4132
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt3)

<400>  4132
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggcug cagccaucgg cauugaccug gggaccacau      120

acagcugcgu gggagucuuc cagcacggua aaguugagau aaucgcgaac gaucaaggca      180

auagaacuac gcccuccuau guggcuuuua ccgacacaga aaggcucauu ggggaugccg      240

caaagaacca gguagcccuu aauccucaga acacuguguu cgacgcuaaa cggcugaucg      300

gacgcaaguu uggcgaucca gucgugcagu cugacaugaa acauuggccg uuccaaguua      360

uuaaugaugg ugacaagccc aaggugcagg ucucauacaa aggggagacc aaggcauuuu      420

auccugaaga gaucaguagc augguguuga caaaaaugaa ggaaauagcc gaggcuuacu      480

uaggauaucc aguaaccaac gccguuauca cugugcccgc guacuucaau gauucccagc      540

gacaggcaac aaaagacgcc ggcgucauug cuggccugaa cgugcuacgu aucauuaaug      600

agccuaccgc cgcagcuauc gccuaugggc ucgauagaac gggaaagggu gaaaggaacg      660

ugcugauauu ugaccuuggc gggggaacuu ucgaugucuc uauucugacc aucgacgacg      720

gcauuuuuga gguuaaggcg acagccggug auacucaccu ugggggagaa gacuucgaua      780

aucggcucgu gaaccauuuu guagaggagu ucaaacgcaa gcacaaaaag gacaucucgc      840

aaaauaaaag agcagugagg cggcugcgca ccgcuuguga acgagccaag agaacacugu      900

caagcaguac ccaggcuucc cucgagaucg auucuuuauu ugaaggcauu gacuucuaca      960

cgagcauaac uagggcccgg uucgaggaac ugugcuccga ucuuuuucgu ucaacauugg     1020

agccagucga gaaagcacug cgcgacgcca agcuagauaa ggcucagauc caugaccucg     1080

ugcugguugg cgggaguacc cggauuccca aagugcagaa guugcugcaa gauuucuuua     1140

acggaaggga cuugaauaaa agcaucaacc cugacgaagc ggucgcauac ggugccgcug     1200

ugcaggccgc aauacucaug ggcgauaagu cugagaacgu acaggaccug uuacugcucg     1260

auguugcccc acuuucccug ggguuggaaa cugcuggagg cgugaugaca gcccuaauua     1320

aaagaaauuc aaccaucccg acgaagcaaa cccagaucuu cacaacuuau agcgacaacc     1380

agcccggugu ccugauucag guguacgagg gggaacgagc aaugaccaag gauaauaacc     1440

uccugggccg cuuugagcuu aguggaaucc cuccagcgcc cagaggcguc ccucaaauug     1500

aggugacauu cgacauagau gcuaauggga uccugaacgu uacugccacc gacaaaucua     1560

caggaaaggc aaauaaaauu accaucacua acgauaaggg uagguugucc aaagaagaga     1620

ucgaacggau ggugcaggag gccgaaaagu auaaggcuga ggacgaggua cagcgcgaaa     1680

gagucagcgc caaaaaugca cucgagucgu acgcuuuuaa caugaagucu gccguggaag     1740

augagggccu gaaagggaag auuuccgagg cggacaaaaa gaagguuuua gauaaauguc     1800

aggaagugau aucauggcug gacgccaaua cgcuagcuga gaaggacgag uucgaacaca     1860

aaaggaagga acucgagcaa gucugcaacc caaucauuag uggacuguau cagggcgccg     1920

gugggcccgg cccgggaggc uuuggggcac agggaccuaa agguggcagc ggguccggac     1980

ccacaaucga ggaaguggau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4133
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt3)

<400>  4133
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggcug cagccaucgg cauugaccug gggaccacau      120

acagcugcgu gggagucuuc cagcacggua aaguugagau aaucgcgaac gaucaaggca      180

auagaacuac gcccuccuau guggcuuuua ccgacacaga aaggcucauu ggggaugccg      240

caaagaacca gguagcccuu aauccucaga acacuguguu cgacgcuaaa cggcugaucg      300

gacgcaaguu uggcgaucca gucgugcagu cugacaugaa acauuggccg uuccaaguua      360

uuaaugaugg ugacaagccc aaggugcagg ucucauacaa aggggagacc aaggcauuuu      420

auccugaaga gaucaguagc augguguuga caaaaaugaa ggaaauagcc gaggcuuacu      480

uaggauaucc aguaaccaac gccguuauca cugugcccgc guacuucaau gauucccagc      540

gacaggcaac aaaagacgcc ggcgucauug cuggccugaa cgugcuacgu aucauuaaug      600

agccuaccgc cgcagcuauc gccuaugggc ucgauagaac gggaaagggu gaaaggaacg      660

ugcugauauu ugaccuuggc gggggaacuu ucgaugucuc uauucugacc aucgacgacg      720

gcauuuuuga gguuaaggcg acagccggug auacucaccu ugggggagaa gacuucgaua      780

aucggcucgu gaaccauuuu guagaggagu ucaaacgcaa gcacaaaaag gacaucucgc      840

aaaauaaaag agcagugagg cggcugcgca ccgcuuguga acgagccaag agaacacugu      900

caagcaguac ccaggcuucc cucgagaucg auucuuuauu ugaaggcauu gacuucuaca      960

cgagcauaac uagggcccgg uucgaggaac ugugcuccga ucuuuuucgu ucaacauugg     1020

agccagucga gaaagcacug cgcgacgcca agcuagauaa ggcucagauc caugaccucg     1080

ugcugguugg cgggaguacc cggauuccca aagugcagaa guugcugcaa gauuucuuua     1140

acggaaggga cuugaauaaa agcaucaacc cugacgaagc ggucgcauac ggugccgcug     1200

ugcaggccgc aauacucaug ggcgauaagu cugagaacgu acaggaccug uuacugcucg     1260

auguugcccc acuuucccug ggguuggaaa cugcuggagg cgugaugaca gcccuaauua     1320

aaagaaauuc aaccaucccg acgaagcaaa cccagaucuu cacaacuuau agcgacaacc     1380

agcccggugu ccugauucag guguacgagg gggaacgagc aaugaccaag gauaauaacc     1440

uccugggccg cuuugagcuu aguggaaucc cuccagcgcc cagaggcguc ccucaaauug     1500

aggugacauu cgacauagau gcuaauggga uccugaacgu uacugccacc gacaaaucua     1560

caggaaaggc aaauaaaauu accaucacua acgauaaggg uagguugucc aaagaagaga     1620

ucgaacggau ggugcaggag gccgaaaagu auaaggcuga ggacgaggua cagcgcgaaa     1680

gagucagcgc caaaaaugca cucgagucgu acgcuuuuaa caugaagucu gccguggaag     1740

augagggccu gaaagggaag auuuccgagg cggacaaaaa gaagguuuua gauaaauguc     1800

aggaagugau aucauggcug gacgccaaua cgcuagcuga gaaggacgag uucgaacaca     1860

aaaggaagga acucgagcaa gucugcaacc caaucauuag uggacuguau cagggcgccg     1920

gugggcccgg cccgggaggc uuuggggcac agggaccuaa agguggcagc ggguccggac     1980

ccacaaucga ggaaguggau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4134
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt3)

<400>  4134
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaccgcua agggcaucgc aauugggaua gaccugggaa      120

caacuuacag cugcgugggu gucuuccagc acggcaaagu ugagaucauu gccaacgauc      180

aagggaauag aacgaccccc uccuaugugg cguuuacaga cacugaaagg cucaucggag      240

augcugccaa gaaccaggua gcaaugaauc cucagaacac cguguucgac gccaaacggc      300

uuauuggccg caaguuuaau gauccagucg ugcaggcuga caugaaacug uggccguucc      360

aaguuaucaa cgaggguggg aagcccaagg uguuggucuc uuacaaagga gaaaauaagg      420

cauuuuaucc ugaggaaaua ucaaguaugg uguuaacaaa acugaaggag accgccgagg      480

cuuuccuagg ccauccagua acuaacgccg uuaucacagu gcccgcguac uuuaaugaua      540

gccagcgaca ggcaaccaaa gacgccggcg ucauugcugg gcucaacgug cugcguauca      600

uuaaugaacc uacggccgca gcuaucgccu auggacuuga uaaggguggc cagggggaga      660

gacacgugcu gauauucgac uugggaggcg guacuuuuga ugucuccauu cucaccaucg      720

acgaugggau uuucgaaguu aaggcgacag ccggagacac ucaucugggc ggcgaggacu      780

uugauaacag gcuggugucu cacuucguag aggaauuuaa acggaagcau aaaaaggaca      840

ucucgcaaaa uaaacgcgca gugagaaggc uccggaccgc uugugagcgc gccaagcgaa      900

cauuaucaag caguacccag gcuaaccugg aaaucgauuc ccuuuacgag gggauugacu      960

ucuauacguc uauaacuaga gccagguucg aagaguugug cgcagaucug uuucggggaa     1020

cacuagagcc agucgaaaaa gcccuccgug acgcuaagau ggauaaggcg aaaauccacg     1080

acauugugcu gguugguggc agcacccgca uccccaaggu gcagagacuu cugcaggauu     1140

acuucaaugg gagggacuug aacaaaucca uaaacccuga ugaggcaguc gccuacggag     1200

cugccgugca agcagccauu cucaugggcg acaagucaga aaaaguacag gaccuguuac     1260

ugcucgaugu ugcuccacuu agucuggguu uggagacugc cgggggcgug augacagcac     1320

uaaucaagcg gaauagcacc aucccgacga agcagaccca aauuuuuaca acuuauucug     1380

acaaccagcc cggaguccug auccaggugu acgaaggcga gcgagcgaug accaaagaua     1440

auaaccuccu ggggcgcuuc gaccuuacag ggauuccucc agcucccaga ggugucccuc     1500

agauagaggu gacuuuugau aucgacgcca auggcauucu gaacguuacc gcaacagaua     1560

aguccaccgg gaaagugaau aagaucacua ucacgaacga caaaggaagg uugucaaagg     1620

aagagauuga acggauggua cucgaugccg agaaguauaa agcugaagac gagguccaac     1680

gcgagaagau agccgcuaaa aaugcacugg aaagcuacgc cuucaacaug aagagugugg     1740

uuucugauga gggcuuaaaa gguaagaucu ccgaaagcga caagaauaaa auucuggaua     1800

aguguaacga gcuacucucg uggcuggagg ugaaucagcu ugcggaaaaa gacgaguuug     1860

accacaagag aaaagaauug gagcagaugu gcaacccaau cauuacaaag cuguaucagg     1920

gaggcuguac cggacccgcc ugcggcacug gguacguccc gggaaggccu gcuaccgguc     1980

ccacaaucga agagguggau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4135
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt3)

<400>  4135
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgccagag gccccgcuau cgggauugac cugggaacca      120

cauacuccug cguggguguc uuccagcacg gcaagguuga gauaaucgca aacgaucaag      180

ggaauaggac uacgccuucu uauguggccu uuaccgacac agaacggcuc auuggagaug      240

cggcuaaaaa ccagguagcc augaauccaa cuaacaccau cuucgacgca aagcgccuua      300

uuggccgaaa auuugaggau gccacagugc agucagacau gaagcauugg ccguuccgug      360

ucgugaguga aggugggaaa cccaagguuc agguggagua caagggagaa accaaaacau      420

uuuucccuga ggagaucagc uccauggucc ugacuaagau gaaagaaaua gcugaggcau      480

auuugggcgg caaggugcac ucugccguaa ucaccguucc agcuuacuuu aaugauucgc      540

aaagacaggc cacgaaagac gcggggacua uuaccggauu aaacgugcug aggaucauua      600

augaacccac agcagccgcu aucgccuaug gucuagauaa gaagggcugu gcagggggag      660

agaaaaacgu ccucauauuc gaccugggcg gugggacuuu ugauguguca auucuuacca      720

ucgaggacgg aauuuucgaa gucaagagca cagcuggcga uacccaucug ggcggggagg      780

acuuugacaa ucggauggug agucacuugg ccgaagaguu caaacgcaag cauaaaaagg      840

auaucggacc uaacaaaaga gcgguuaggc ggcuccgcac ggccugcgaa cgagcaaaga      900

gaacucuguc cucuagcaca caggcuucca ucgagauuga cucacuguac gagggugugg      960

auuuuuauac caguauaacu agggcccggu ucgaggaacu caaugcugac uuauuccgug     1020

gcacacugga accaguagag aaggcccuuc gcgaugcaaa auuggacaag gggcagaucc     1080

aagaaauugu gcuggucgga ggcagcacca gaauccccaa aauacagaag cuacuccagg     1140

acuuuuucaa cgguaaagag cugaauaagu cuauuaaccc ugaugaggcc guggcuuacg     1200

gggcggcagu ucaggccgcu auccuuaucg gcgauaaguc cgaaaaugug caagaccugu     1260

ugcuccugga ugucacgcca uuaucacugg gaauugagac cgccggcggg gugaugacac     1320

cgcucaucaa aaggaacacu accauuccca caaagcagac ucagaccuuu acaaccuaca     1380

gcgacaacca aaguucugua cuuguucagg uguaugaagg agagcgggca augacuaaag     1440

acaauaaccu guuggguaag uucgaucuaa cgggcauacc uccagcuccc cgaggggucc     1500

cucagaucga agugacauuu gacauugaug ccaauggaau ccugaacguc accgccgcag     1560

acaaauccac uggcaaggag aauaagauca ccauuacaaa cgauaaaggu cgccucagca     1620

aggacgauau agacagaaug gugcaggagg cggaaaggua caaaucggag gaugaagcua     1680

aucgggaccg cguugccgca aagaacgccc uggagucuua uaccuacaau aucaaacaaa     1740

cuguggagga ugaaaaacuu agagggaaga uuuccgagca ggacaagaac aagauccugg     1800

auaaauguca ggaaguaauu aauugguugg acaggaacca gauggcugag aaggacgaau     1860

augagcacaa acaaaaggag cucgaacgug ucugcaaucc aaucauauca aaacuguacc     1920

agggcggacc cggcggggga agugguggcg ggggaagcgg cgccuccggu gggccgacaa     1980

ucgaggaagu ggauugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  4136
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt3)

<400>  4136
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccag uccugcuacg      120

uugccguggc uagagcagga gguauugaga ccauagccaa cgaauauucu gauaggugua      180

cacccgcgug caucucauuu ggcccuaaga aucggaguau uggggcugcc gcaaaaagcc      240

aaguaaucuc caacgccaag aauacugugc agggauucaa acgcuuucac ggccgagcuu      300

ucucugaccc auuugucgag gcagaaaagu cgaaccucgc cuacgauauu gugcagcuuc      360

cgacgggucu gaccgggauc aaaguuacau auauggagga agaacguaau uucacuaccg      420

aacaggugac agcuauguug uuaucaaagc ugaaggaaac cgccgagagc guccucaaaa      480

agcccguggu agacuguguu gugagugucc cuugcuuuua cacugaugcg gaaagaaggu      540

ccgugaugga cgcaacacaa auagccggac uaaacugucu gcggcuuaug aaugagacca      600

cggcuguggc ccuggcauau ggcaucuaca aacaggauuu gccagcucuc gaggaaaagc      660

cccgcaacgu cguuuucgug gacaugggcc auucugccua ucagguaagc gugugcgcgu      720

uuaauagagg gaaacugaag guccuggcca cugcauucga uaccacacuc ggagguagga      780

aguuugacga gguguuaguu aaccacuucu gugaagaguu uggcaaaaag uacaaacugg      840

auauuaaguc caaaauccgg gcucuuuugc gccugucaca ggaaugcgag aagcucaaaa      900

agcuaaugag ugccaaugcu agcgaccugc cucuuucuau ugaguguuuc augaacgaug      960

uggacgucuc cgggacuaug aaucgaggaa aguuccugga aaugugcaac gacuugcucg     1020

ccagagugga gccaccccug aggucaguau uagaacaaac caaacugaag aaagaggaua     1080

ucuacgcagu ugaaauagug ggcggugcca cacggauucc ugcugucaag gagaaaauca     1140

gcaaguuuuu cgggaaggag cucaguacca cgcuuaaugc ggacgaagca gugacucgug     1200

gaugugcccu gcagugcgcu auuuugucuc cagccuuuaa aguccgcgag uucuccauca     1260

cagauguggu uccguauccc aucagccuaa gauggaacuc gccugcagaa gaggggucuu     1320

ccgacugcga aguguuuuca aagaaccaug ccgcuccauu caguaaagua cugaccuuuu     1380

acaggaagga gcccuucacu cucgaggccu auuacagcuc cccucaggau cugccauauc     1440

ccgacccggc aauugcgcag uuuucugucc aaaaagugac accucagagc gauggcucaa     1500

guuccaaggu uaaggugaaa guccggguga auguacacgg cauauucagc gugucuucag     1560

cuagucuugu ugaaguccau aagagcgagg aaaacgagga gcccauggaa accgaccaga     1620

augccaaaga ggaagagaag augcaagugg aucaggagga gccacacgug gaggaacagc     1680

agcaacagac gccugcagag aacaaagccg aauccgagga aauggagacc ucucaggcug     1740

gaucgaagga caagaaaaug gaucagcccc cacaagccaa gaaagcaaag gucaaaacaa     1800

gcacuguuga ccugcccauc gagaaucagu ugcucuggca gauugaccga gaaaugcuga     1860

acuuauacau cgagaaugaa gguaagauga uaaugcagga uaaacuggag aaggaacgca     1920

acgacgcuaa gaaugccgug gaggaguaug uguacgaaau gagagauaaa cuauccggcg     1980

aguacgaaaa guuuguauca gaggacgaua ggaacaguuu cacccucaaa cuggaggaca     2040

cagaaaauug gcuuuaugag gauggggaag accaaccuaa gcaggucuac guggauaaau     2100

uggcggagcu gaagaaccuc ggacagccaa uuaagauccg guuucaggaa ucugaggagc     2160

gcccgaaacu guucgaggag cuuggcaagc aaauccagca guauaugaaa auuaucagcu     2220

ccuucaagaa uaaagaagac caauacgauc accuggacgc cgcugauaug acuaagguug     2280

agaagucaac caacgaagca auggagugga ugaauaacaa auugaaccuc cagaauaagc     2340

agagccugac aauggacccc guggucaaau cuaaggagau ugaagccaaa auaaaggagu     2400

uaaccuccac uuguaguccu aucauuagca agccaaaacc caagguggaa ccuccaaaag     2460

aggaacagaa gaacgcugag caaaaugguc ccguugacgg gcagggcgau aacccgggac     2520

cucaggccgc agagcagggc acggacacag cggugccauc ugauuccgac aaaaagcugc     2580

ccgaaaugga uaucgacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  4137
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt3)

<400>  4137
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccuc aacugcuaca      120

uugccguugc uagauccgga gguauagaga ccaucgcaaa ugaauauucu gauaggugua      180

cacccgccug cauuucacuu ggcagucgga cucgcgcgau cgggaacgcu gccaagagcc      240

agauugugac gaauguacga aacaccaucc acggauuuaa aaagcugcau ggccguuccu      300

ucgacgaucc uauagugcaa acagagagaa ucagguugcc auacgaauua cagaaaaugc      360

cgaaugguuc ugcagggguc aaggugcggu aucuggagga agagagaccc uuugccauug      420

agcagguuac uggaaugcua cucgcuaaac ugaaggaaac cucggagaac gcacuuaaga      480

aaccuguggc cgacuguguc aucucaauuc ccagcuucuu uacagaugcu gaaagaagga      540

gugugauggc cgcggcacag guagccggcc ugaauugcuu gcggcucaug aacgagacca      600

cugcuguugc ccuggcauac ggcaucuaua agcaagaccu gccaccucuc gaugagaaac      660

cacgcaaugu ggucuucaua gacauggggc acuccgcuua ccagguguua gugugugccu      720

uuaacaaggg aaaacugaag guccuugcga caaccuucga ucccuauuug gguggccgaa      780

auuuugacga agcccugguu gauuacuucu gcgacgaguu uaagacgaaa uacaagauua      840

acgugaaaga aaauucuaga gcacuacuca ggcuguauca ggagugugaa aaacuuaaga      900

agcugaugag cgcuaacgcc uccgauuugc cucucaauau cgagugcuuc augaacgacc      960

uggacguauc aaguaaaaug aaccgggcuc aguuugagca auuaugugcc agccugcucg     1020

cacgugugga accaccgcuu aaggccguca uggagcaggc uaaucugcag cgcgaagaua     1080

uuucuuccau cgagaucguu gggggagcga cucgcauucc cgcagugaag gaacagauaa     1140

ccaaauucuu cuugaaggac aucucaacaa cucuaaacgc cgaugaggcu guggccaggg     1200

gcugcgcacu gcaaugugcc auucucagcc cugcuuuuaa aguccgggag uucaguauca     1260

ccgaccuggu gccauacucu auaacacuuc gauggaagac cuccuuugaa gaugguagcg     1320

gggagugcga aguauucugc aaaaaucauc ccgccccuuu uucgaagguu auuacguucc     1380

acaagaaaga gccauuugaa cuggaggcau ucuauacuaa cuugcaugag gugcccuacc     1440

cggacgcgcg caucggaucu uuuacaaucc agaaugucuu cccucagucc gauggcgacu     1500

caaguaaggu gaaagucaag gugagaguua acauucacgg caucuuuagc guggcuuccg     1560

ccucuguaau ugaaaaacaa aaucucgagg gggaucacag cgacgcaccc auggaaaccg     1620

agacuucauu caagaacgag aauaaggaua acauggacaa aaugcagguc gaccaggaag     1680

agggacauca gaagugucac gccgaacaua caccagagga agagauagau cacaccggug     1740

cuaaaacgaa gagugccgug uccgacaaac aagauaggcu gaaucagacc uuaaagaagg     1800

gcaaaguuaa gagcaucgac cugccuauuc agucuucacu augccggcag cucgggcaag     1860

aucugcuuaa caguuauauc gagaaugaag gaaaaaugau caugcaggac aaguuggaga     1920

aagaacgcaa cgaugcaaag aaugcugugg aggaauacgu cuaugacuuu agagauaggc     1980

ugggcacagu guacgagaaa uucauuacuc ccgaggaccu cagcaagcug uccgccguac     2040

uugaagauac cgagaacugg cuguacgaag acggugagga ucagccaaaa cagguguaug     2100

uugacaaguu gcaagaacuc aagaaauacg ggcagcccau acagaugaag uauauggagc     2160

acgaggaacg uccuaaagcg cugaacgacu uaggcaagaa gauccagcug gucaugaaag     2220

ugauugaggc cuaccggaau aaggaugaac gauaugacca ucuagaucca acagagaugg     2280

agaaagugga aaaguguauc ucugacgcua ugucguggcu caacagcaaa augaaugcac     2340

aaaacaagcu gucccuuacu caggauccgg ucguuaaggu gucagagauu guggccaaaa     2400

guaaggaauu ggacaauuuc ugcaacccca ucauauacaa accuaagcca aaagcugagg     2460

uacccgaaga uaagccuaag gccaauucug agcacaacgg accaauggac ggccagagcg     2520

ggaccgagac aaaauccgau ucaaccaagg acagcucuca acauacuaaa uccaguggag     2580

aaauggaggu cgauugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  4138
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt3)

<400>  4138
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugagcc ucguggccgc uaugcuucug uuguuauccg      120

cagccagagc ggaggaagag gacaaaaagg aagaugucgg caccguugug gggaucgacc      180

ugggaacaac uuacucuugc guaggugugu ucaaaaacgg cagggucgag auuauagcua      240

augaucaggg gaaccggauc acgcccucau auguggccuu uaccccugaa ggagagcgcc      300

uaauuggcga cgcagccaag aaucaacuca caaguaaccc agagaauacu guuuucgaug      360

cuaaacgacu gaucggucgu accuggaacg acccgagcgu gcagcaggau auuaaguuuc      420

uucccuucaa ggucguggaa aagaagacaa aaccuuacau ccagguagac auagggggag      480

gccaaaccaa gacuuuugca ccagaggaaa ucuccgccau gguucugaca aaaaugaagg      540

agaccgcuga ggccuauuug ggcaagaaag ugacgcacgc ggucgugacu gugcccgcau      600

acuucaauga ugcccagaga caggcuacca aggacgccgg gacaauugca ggacucaacg      660

ucaugaggau cauuaaugaa ccuacugcug ccgcgaucgc cuauggucug gauaaacggg      720

agggcgaaaa gaacauacug guuuuugacc ucgggggagg caccuucgau gugucuuuac      780

ugacaauuga caauggugua uuugaggugg ucgcaaccaa cggggacacg caucuuggag      840

gcgaagauuu cgaccagcgc gugauggagc acuuuaucaa auuguacaag aaaaagacug      900

gcaaggaugu uagaaaagac aauagggcug ugcaaaagcu gcggcgcgag gucgaaaaag      960

ccaagcgagc ucuaucguca cagcaucagg ccagaauuga gaucgaaucu uucuaugagg     1020

gggaagauuu uagugagaca cucaccaggg caaaauucga ggaacugaac auggaccuuu     1080

uccgguccac uaugaagcca gugcagaagg uacuggagga uucugacuug aaaaagagcg     1140

auaucgacga aauuguucuc gugggagguu ccacacguau acccaaaauc caacagcugg     1200

ucaaggaguu uuucaauggc aaagaaccuu cacgcgggau uaacccagau gaggccgugg     1260

cuuacggagc ggcaguccag gccggcgugu uaagugguga ccaagacacc ggggaucugg     1320

uucuccuuga cguguguccg cugacguugg gcaucgagac cguaggaggc gucaugacaa     1380

agcuaauacc cagaaacacu gugguuccua ccaagaaaag ccagauuuuu agcacagcuu     1440

ccgauaauca gccaacugug accaucaagg ucuacgaagg ggagaggccc cugacaaaag     1500

acaaccaccu ccugggaacc uucgaucuua cugguauccc uccagcaccc cggggcgugc     1560

cgcagauuga aguaacguuu gagaucgacg ugaaugggau ucugcgaguu acagccgagg     1620

auaagggaac cggcaacaaa aauaagauaa cuaucaccaa cgaccaaaau cgcuugacac     1680

cugaagagau ugaaagaaug gucaacgaug ccgagaaguu cgcugaagag gacaaaaagc     1740

ucaaagagag gaucgauacc cggaaugaac uggagucaua ugccuacagc uuaaagaacc     1800

agaucgguga caaagaaaag cuagggggca aacugaguuc ugaggauaag gaaacuaugg     1860

agaaggcagu ggaggagaaa auugaauggc ucgaauccca ucaggacgcg gacauagagg     1920

auuuuaaggc uaaaaagaaa gaacuggagg agaucgugca gcccauuauc agcaaacuuu     1980

auggaucggc cggcccaccu cccacagggg aagaggacac ggcagaaaag gaugaguugu     2040

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  4139
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt3)

<400>  4139
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gagagcuggc ugugggcauc gaccucggga      120

ccacauacag cugcgucgga guuuuccaac aggguagggu ggaaauucuu gcaaacgauc      180

agggcaaucg gacuacgccu uccuauguag ccuuuaccga cacagagcgc cugguggggg      240

augcggcuaa gucucaggcc gcauugaacc cacacaauac ugucuucgac gccaaacgau      300

uaauaggacg uaaguuugcu gauaccacag ugcaaucaga caugaaacau uggccguuca      360

gaguugugag ugaaggcggu aagcccaaag ucagggugug uuaccgcggg gaggauaaga      420

ccuuuuaucc ugaagagauc agcuccaugg uacugucuaa gaugaaagag acugcagaag      480

ccuaccuagg acagccaguu aagcacgcug ugauuacagu ccccgccuau uucaacgacu      540

cgcagcggca ggcgaccaaa gaugcaggcg ccaucgcugg ccucaaugug cugagaauua      600

ucaacgagcc uacggccgca gcuauagccu acgggcuuga caggcgggga gcgggugaac      660

gcaaugugcu gaucuuugau uugggcgggg gaacuuucga cgucucaguu cucagcauug      720

augccggcgu guuugaggua aaggcaaccg cuggugacac acaucucggg ggagaggacu      780

ucgauaaccg acuggugaau cacuuuaugg aagaguucag aaggaaacau ggcaaggacc      840

ugaguggcaa caagcgggcc uuacgucgcc ugagaacugc uugcgaaagg gccaaacgga      900

cccuuuccuc uagcacacaa gcaaccuugg agaucgauuc ccuguuugaa ggggucgacu      960

ucuauacguc aauuacucga gcccgcuucg aggagcuaug uagugaucuc uuuagaagca     1020

cacuggaacc aguggagaag gcucuuaggg acgcgaaacu ggauaaggca cagauccacg     1080

acguuguguu ggucggaggu ucuacccgga uacccaaagu gcagaagcuc cugcaggauu     1140

ucuuuaaugg caaagaauua aacaagucca uuaauccuga cgaggccgua gcuuacgggg     1200

ccgcaguuca agccgcugug cugaugggag auaagugcga aaaaguccag gaccuccuuc     1260

uguuggacgu ggccccacua ucacugggcc ucgagacugc cggugggguc augacaaccc     1320

ugauccagcg caacgcgacg auuccgacca agcaaacaca gacuuucacc acauacagcg     1380

auaaucagcc cggcguguuu auccagguuu augagggaga aagagcuaug acuaaagaca     1440

acaaccuucu gggcagguuc gaguugagug ggaucccucc agcaccccgu ggagugccuc     1500

aaauugaagu aaccuuugau auagacgcaa augguauccu cucugucaca gccaccgauc     1560

gguccacugg caaggcuaac aaaauuacga ucacaaauga caaggggcga cugagcaagg     1620

aggaagugga gagaaugguu cacgaggccg aacaguacaa agcagaggau gaagcucaga     1680

gggaccgcgu ggccgcgaag aacucguuag aggcccaugu cuuccacgug aaaggaucuc     1740

ugcaggagga aucccuacgg gauaagauac cagaggaaga cagaaggaaa augcaagaua     1800

agugucgcga gguacucgcu uggcuggaac auaaucagcu ugcagagaag gaggaauaug     1860

agcaccagaa acgagaauug gagcagauuu gccggcccau cuuuucacgu cuguacggcg     1920

guccgggggu gccuggcgga aguagcugug gcacccaagc cagacagggg gaccccucca     1980

cuggaccaau cauugaagag guugauugag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  4140
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt3)

<400>  4140
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gagagcuggc ugugggcauc gaccucggga      120

ccacauacag cugcgucgga guuuuccaac aggguagggu ggaaauucuu gcaaacgauc      180

agggcaaucg gacuacgccu uccuauguag ccuuuaccga cacagagcgc cugguggggg      240

augcggcuaa gucucaggcc gcauugaacc cacacaauac ugucuucgac gccaaacgau      300

uaauaggacg uaaguuugcu gauaccacag ugcaaucaga caugaaacau uggccguucc      360

agguugugag ugaaggcggu aagcccaaag ucagagugug uuacagggga gaggauaaga      420

ccuuuuaucc ugaagagauc agcuccaugg uacugucuaa gaugaaagag acugcagaag      480

ccuaccuagg gcagccaguu aagcacgcug ugauuacagu ccccaccuau uucucgaacu      540

cacagcggca agccacgaaa gacgcgggcg caaucgccgg ccucaaggug cugccuauua      600

ucaaugaggc uacugccgca gcuauagccu acgggcuuga ucgcagagga gcggguaaaa      660

ggaacgugcu gaucuuugac uugggcgggg gaaccuucga ugucagcguu cucaguauug      720

acgccggcgu guuugaagua aaggcaacag cuggugauac ucaucuuggg ggagaggacu      780

ucgacaaucg gcuggugaac cacuuuaugg aggaguuccg ccgaaagcau ggcaaagauc      840

ucuccggcaa uaagagagcc uuaaggcggc ugcguaccgc uugcgagcgc gccaaaagaa      900

caccaucuag cuccacccag gcaacgcuug aaaucgacuc auuguuugag ggggucgauu      960

ucuauaagag uauuacuagg gcccgguucg aagaacugug uagcgaccua uuucgaucua     1020

cacucgagcc cguggaaaaa gcucugcgcg augcgaagcu ggacaaagca cagauccacg     1080

auuucguucu gggagguggc uugcacuccc auccucaggg ggccgaggug gcugccggac     1140

uccugcaaag acagggcgca gaacaggagc accaaccaug aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  4141
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt3)

<400>  4141
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaagggcc ccgccguggg gaucgaccug ggaaccacau      120

acuccugcgu cgguguuuuc cagcacggca aaguggagau uauagcuaac gaucaaggga      180

auagaacuac gccuucuuau guagcauuua ccgacacaga aaggcucauc ggagaugccg      240

cgaagaacca gguggcuaug aauccaacua acaccgucuu cgacgccaaa cggcuuauug      300

gccgccgauu ugaugacgca gugguucagu cagauaugaa gcauuggccg uucauggugg      360

ucaaugacgc cggucguccc aaagugcagg uagaguacaa gggggaaaca aagaguuuuu      420

auccugagga aguuagcucc auggugcuga ccaaaaugaa ggagaucgcu gaggcauacu      480

ugggaaaaac ugucacaaac gccgugguga ccgucccagc uuauuucaau gauucucaaa      540

gacaggccac gaaggacgcg ggcacuauug caggcuuaaa cguucugagg aucauaaaug      600

aacccaccgc cgcugccauc gcauacgggc uagauaaaaa ggugggagcu gagcggaacg      660

uacucauuuu ugaccugggu ggcgggacau ucgauguguc gauccuuacu auugaagacg      720

gaaucuuuga ggucaaguca accgccggcg acacacaccu ggguggggag gauuucgaca      780

aucgcauggu gaaccauuuu auagcggaau uuaaaagaaa gcacaaaaag gauauuagcg      840

agaauaaaag ggccguucgg cgcuugcgaa ccgcauguga aagagcuaag aggacgcuca      900

guuccucuac ucaggccagc aucgagauug acucccugua ugaaggaauc gauuuuuaca      960

caucaaucac ccgggcucgu uucgaggagc ugaacgccga ccucuuccgc ggcacuuuag     1020

auccugugga aaaagcacug agagacgcca aacuugauaa gagucagauu caugacauag     1080

ucuugguggg cgggagcaca aggaucccaa agauucaaaa gcugcuacag gauuucuuca     1140

auggaaaaga gcucaacaag ucuaucaacc ccgacgaagc uguagcguac ggugcagccg     1200

uucaggcugc cauacugucc ggcgacaaau cagagaaugu gcaggaucuu cuguugcucg     1260

acgucacccc ucugagcuua gggauugaaa cggcaggagg cgugaugacc guccugauca     1320

agcggaacac aacuauccca accaagcaaa cacagacuuu uaccacauau agugauaauc     1380

agccgggugu gcucauucaa guuuacgagg gggagcgagc caugaccaaa gacaacaauc     1440

uucugggcaa guucgaauug acuggaaucc cucccgcucc acgcggcgug ccccagauug     1500

agguaacguu ugauauagac gccaacggga uccuaaaugu cucugcagug gauaaaucca     1560

caggaaagga aaacaaaauu accaucacua augacaaggg uagacugagc aaggaggaua     1620

ucgaaaggau gguucaggag gcggagaaau auaaggcuga agacgagaaa cagcgggaua     1680

aggugucguc uaaaaacucc cucgaaucau acgccuucaa uaugaaggca accgucgagg     1740

acgagaagcu gcaaggcaaa auuaacgaug aagacaagca gaaaauacuu gacaagugca     1800

augagaucau uaacuggcug gauaaaaauc agacagccga aaaggaggaa uuugagcacc     1860

agcaaaaaga guuggaaaag guguguaacc cuaucauuac caagcucuau cagagugcug     1920

ggggaaugcc aggcgguaug cccgggggcu ucccgggagg cggggccccu cccagcggag     1980

gugcauccuc uggcccaacu aucgaggaag uagacugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  4142
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt3)

<400>  4142
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucagcgccu ccagagcugc agccgcgagg cuggugggcg      120

cugccgcauc ucgggggccc accgccgcuc gccaccagga cucauggaac ggacucaguc      180

augaggcauu ccgacuuguc agccguagag auuacgccuc cgaagcuauu aagggugccg      240

uugugggcau agaccugggg acaacuaauu cuugcguagc ggugauggag ggaaaacaag      300

caaaggucuu ggaaaacgcc gagggcgcua ggacgacccc uucggugguu gccuuuacag      360

cagaugguga acgguuagug gggaugccag cuaaacgcca ggccgucacu aauccgaaca      420

auaccuucua ugcgacaaag agacugaucg gaaggcggua cgacgauccc gaggugcaga      480

aagacauuaa gaacguaccu uuuaagaucg uucgcgccuc aaauggcgau gcaugggugg      540

aggcucacgg caaacuauau agcccaaguc agauuggggc cuucguccuc augaagauga      600

aagaaaccgc ugagaacuac cugggacaua cugccaagaa ugcagugauc acagugcccg      660

ccuauuuuaa cgacucccaa cgacaggcua ccaaagaugc gggucagaua ucuggccuua      720

auguccugag aguuaucaac gaaccuacgg cagccgcuuu ggccuacggg cucgacaaga      780

gcgaggauaa ggugauugca guauaugacc ugggaggcgg uacuuucgau aucuccauuc      840

uggagaucca gaaaggggug uuugaaguca agucaaccaa uggagacaca uuccucggcg      900

gcgaggacuu ugaucaagcc uuacugaggc acauagugaa agaguucaag cgggaaacug      960

ggguugaccu uaccaaagau aacauggcuu ugcagcgugu gcgcgaagcc gcagagaagg     1020

cgaaauguga gcugaguagc ucuguccaga cagacauuaa ucuaccauac cucaccaugg     1080

auuccucagg acccaagcau cugaacauga aguugacgag agcucaguuu gaagguaucg     1140

ugacugaccu gauuaggcgg acaaucgccc cuugccaaaa agcaaugcag gaugccgagg     1200

uaagcaagag ugacaucggc gaaguuauuu uggucggggg aaugacccga augccaaaag     1260

ugcagcaaac ugugcaggau cucuucggcc gcgcuccguc uaaggccguc aaccccgacg     1320

aggcaguggc uauaggugcc gcgauccaag ggggcguucu ggccggagau gugacagacg     1380

uauuacugcu cgacgucacc ccucuuuccc ugggcauuga aacgcuuggg ggaguguuua     1440

ccaaacuaau caauagaaac acaacuauac caaccaaaaa gagccagguu uucucgacag     1500

cugcagaugg ucagacucag guggagauua aggucuguca gggcgagagg gaaauggccg     1560

gggacaauaa gcugcucgga caguucaccc ugaucggcau ucccccugcu ccacggggug     1620

ugccccaaau cgagguaaca uuugauaucg acgccaacgg gauugugcac guuucugcaa     1680

aagauaaggg caccggacgc gaacagcaga uagucaucca guccucaggc gggcuuagua     1740

aagacgauau ugagaauaug gugaagaacg cggaaaagua cgccgaggag gacagaagga     1800

aaaaggaacg uguggaggcu gucaauaugg ccgaaggaau cauccacgau acugagacga     1860

aaauggagga guucaaggac caacugccgg cagaugaaug caacaaauug aaggaagaga     1920

uuagcaagau gcgggaacuc cuggcucgaa aagacuccga gacaggugag aauauaagac     1980

aggccgcauc uagcuuacag caggccucac ugaagcuauu ugaaauggcu uauaaaaaga     2040

uggcgaguga gagggaaggc uccgggagcu cuggaaccgg cgagcaaaaa gaagaucaga     2100

aggaggagaa acagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  4143
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt3)

<400>  4143
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg aggcuggcgg gagcgaugga cccagagaaa      120

ccgcaccuac auccgccuac ucuucaccag cgaggagucu gggugacacu ggcaucacgc      180

cgcucagccc cucccacauu gugaacgaua ccgacucuaa ugucucggag cagcaaucau      240

uccuuguugu gguagcugug gauuuuggga caacuagcag uggauaugcc uacuccuuca      300

ccaaagaacc ugagugcaua caugucaugc ggcgcuggga aggcggugac ccaggggugu      360

cuaaccagaa gacacccacc acuauccugu ugacaccuga gcgaaaauuu cacagcuucg      420

gauaugcagc ccgugauuuu uaccaugacu uagauccaaa ugaggcuaag caguggcugu      480

aucuagaaaa auucaagaug aagcuccaca ccacgggcga ccugacuaug gauaccgacc      540

uuacagcagc caacggcaaa aagguuaaag cucuggagau uuuugccuac gcguugcagu      600

auuucaagga acaagcacuc aaagagcugu ccgaucaggc cgggucagag uuugaaaaua      660

gugacgugag augggucauc acugugcccg cuauuuggaa gcagccugcc aagcaguuca      720

ugaggcaagc agcuuaccag gccggacugg cgagcccaga gaacucugaa cagcucauca      780

uagccuuaga gccggaagca gcuuccaucu acugucggaa acugcgccuu caucagauga      840

uugaguuguc aagcaaggcc gcuguaaaug guuauagugg cucugacacc guuggggccg      900

gauuuacaca agcaaaagag cacaucagaa ggaaccggca gucccgcacc uuccuggugg      960

aaaaugucau uggcgagauc uggagcgaac uagaggaagg ugauaaguac gugguggucg     1020

acuccggggg aggcacgguu gaucucacug ugcaccagau acgacugccc gagggccauc     1080

uuaaagagcu guauaaggcc acagggggac cuuacgguuc uuugggcgua gacuaugaau     1140

uugagaaacu ccuguacaag auuuucgggg aagauuucau cgagcaauuu aagauuaaaa     1200

gaccagcugc guggguggac uuaaugaucg cauucgaauc caggaagcgg gccgcugccc     1260

ccgaucguac caacccucug aauaucacuc ucccauuuuc auucauugac uauuacaaaa     1320

aguuucgcgg acacaguguc gagcaugcac uuagaaaaag caacguggau uucguuaagu     1380

gguccucuca gggcaugcug aggaugagcc ccgacgccau gaaugcuuug uuuaagccga     1440

caauagauuc aaucauugag caccuacggg accuguucca gaaaccugaa gugaguaccg     1500

ucaaguuucu cuuccuggug gguggguuug ccgaggcacc ccuucugcag caagcgguac     1560

aggcugccuu cggcgaccag ugccgaauca uaauuccaca ggauguugga uugacgaucc     1620

ucaaaggcgc agugcuguuu ggguuagacc cugccgucau caaggugcgc agaucgcccc     1680

ugaccuacgg agucggugug cuaaacaggu auguugaagg caaacaccca cccgagaagc     1740

uccuggugaa ggaugggaca cgguggugua cugacguauu cgauaaauuc auuagcgcug     1800

accaaucugu cgcccuugga gaguugguga agcgcucaua caccccugca aaaccaaguc     1860

agcugguuau cgugauuaau auauauagcu ccgaacauga uaacgucucu uuuaucacag     1920

acccgggcgu gaagaaaugc gguacucuca gacuggaucu uaccgggaca ucgggcaccg     1980

cuguacccgc caggcgugag auucagacuc ugaugcaguu cggagacacg gaaaucaagg     2040

cgacagccau cgauauugcu accagcaagu ccgugaaagu uggcauagac uuuuugaacu     2100

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  4144
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt3)

<400>  4144
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuggccgugc ccgagauggg ccuccagggg cuuuacaucg      120

gaagcucccc ugaaagaucu ccagucccgu cacccccugg uaguccaagg acccaagaga      180

gcugcggcau ugcuccccug acaccuuccc agucuccaaa gcccgaaguu cgggcaccuc      240

agcaggccuc guucucagug guaguggcga uagacuuugg gacuacgagc aguggauaug      300

cuuucuccuu ugccucugau ccagaggcaa uccacaugau gcgcaaaugg gaaggcggug      360

acccgggggu cgcccaccaa aagaccccca cauguuuguu acugacuccu gagggagcuu      420

uccacagcuu uggcuacacc gcacgagauu auuaccauga ccuagaucca gaggaagccc      480

gugacuggcu cuauuucgag aaauuuaaga ugaaaauuca cuccgcuaca gaucugaccc      540

uuaagacuca gcuggaagcc gugaacggca agacaaugcc cgcguuggag guuuucgcac      600

augcccucag auuuuucagg gagcacgcuc ugcaggaacu gcgggagcag ucaccuaguc      660

ucccagaaaa agacaccgug cgcugggucu uaacggugcc cgccaucugg aagcaaccgg      720

caaaacaguu uaugagagag gcugccuacc uggcggggcu uguaagcagg gaaaaugccg      780

agcaguugcu gauugcacua gagccugaag cugccucugu uuauugccgg aagcuccgcc      840

ugcaccagcu ucuggauuug uccggacgag cucccggugg cgggagacuc ggagagaggc      900

ggucaaucga cagcaguuuc cgucaagccc gcgaacagcu gagaaggucu cggcauuccc      960

gaaccuuuuu aguggagagc ggcgucggug aacugugggc agagaugcag gccggggauc     1020

gcuacguggu ggcugacugu ggaggcggca cugucgaucu cacaguucac caacuugagc     1080

agccacaugg gacucugaaa gaauuguaca aggcgucggg agguccuuau ggcgcagugg     1140

ggguagaccu agccuucgag cagcugcucu gcagaauauu cggagaagac uuuaucgcua     1200

ccuucaagag gcagcggccc gccgcauggg uggaucugac aauugccuuu gaggcucgca     1260

aaagaaccgc cggcccacac agggcgggug cacuuaacau cucucugccc uucuccuuua     1320

uugacuucua ccguaagcaa cgggggcaca augucgaaac ggcuuugcga agaucaagug     1380

ugaacuuugu uaaauggagc ucccagggca ugcucaggau gucuugugag gccaugaaug     1440

agcuguucca gccuacugug agcggaauca uacagcauau ugaagcauua cuggcccgcc     1500

cagaggucca aggcgugaag cuacucuuuc ugguaggggg auucgcugaa ucagccguuc     1560

uucagcacgc agugcaggcu gccuugggug cgcggggccu gagagucgug gucccgcaug     1620

auguggggcu cacaauccug aaaggagccg uucuuuuugg ccaggcuccc ggugugguaa     1680

ggguccgccg aaguccucug accuaugggg ugggcguuuu gaaccgguuc gugccaggac     1740

gucauccccc ugagaagcuc cuggucagag acggcaggcg cuggugcacu gauguguuug     1800

agcgguucgu agcagccgaa caauccgugg cuuuagggga ggaaguuaga aggagcuacu     1860

guccagcccg acccggacag cgccgggucc ugauuaaucu auauugcugu gcagcggagg     1920

acgccagauu caucacagau ccggguguga ggaaaugcgg cgcucucucu cuggaacuug     1980

agccugccga cugugggcag gauaccgcag gagcuccacc cggccgucgc gagauccggg     2040

ccgcaaugca guuuggugac acggaaauua aggugaccgc cgucgauguu ucaacaaaca     2100

gaagugugag ggcuagcaua gacuucuugu ccaauugagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  4145
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt3)

<400>  4145
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgggaga ugaccauccu gggcagcgcu gugcucacac      120

uucuguuggc aggguacuua gcccagcaau aucugccccu accuacucca aaggucauug      180

gaauagaccu cgguacgacc uacugcuccg uuggcguguu cuuuccgggg acaggaaaag      240

uaaaggugau ccccgaugaa aacggccaca uuucuauccc uucaaugguc aguuucacug      300

acaaugaugu guauguuggu uacgagagcg uggaacuggc ggacuccaac ccacagaaua      360

ccauuuauga ugcuaaaagg uuuaucggga agauauucac agccgaggaa cuugaggcag      420

agaucggacg guaccccuuu aaaguccuga acaagaaugg caugguggag uucucuguaa      480

ccucgaacga aacuauuaca guuucaccug aauauguggg cagccgcuug cuccugaagc      540

ugaaagagau ggccgaggcu uaccucggga ugccagucgc aaaugccgug aucagugugc      600

ccgcugaauu ugacuuaaag cagcgaaacu ccaccauuga ggccgcgaau cuggcaggac      660

uuaaaaucuu gcgugucaua aacgaaccua cggccgcugc cauggcauac ggucugcaua      720

aggcugaugu uuuccacgug cuaguaauug accucggcgg gggaacucug gaugugucuc      780

uucugaauaa acagggcggu auguuuuuga ccagagccau gagcgggaac aauaagcucg      840

gaggccaaga cuucaaccag aggcuguuac aguaucugua caagcagauc uaucaaacau      900

acggcuuugu cccaucccgg aaagaggaaa uucaucgccu cagacaggcg guggagaugg      960

uuaaguugaa ucugacuuug caccagucag cccagcuaag ugugcugcuc accgucgagg     1020

aacaagauag gaaagagccg cauagcucug acacagaacu gcccaaggau aaacuuuccu     1080

cagcagacga ccaccgggug aacagcgggu ucggacgcgg ucugagugau aagaaaucug     1140

gcgaguccca gguauuguuu gaaaccgaga ucagccgaaa acucuucgac acgcugaacg     1200

aggauuuauu ccagaagauc cugguuccua uucaacaggu gcuaaaggaa gggcaccucg     1260

agaagacuga aauagacgag gucgugcugg ucggaggcuc gacaagaauc ccaaggauua     1320

gacaggugau ccaggaauuu uucgguaaag aucccaauac cucuguugac ccugaucuug     1380

cugugguaac uggggucgcc auacaagcug gcauugacgg aggcuccugg ccacuucagg     1440

ugucagcccu ggagaucccc aacaagcauc uccagaaaac aaauuuuaac ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4146
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt3)

<400>  4146
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgcuaucg gcgugcaccu ggggugcacc agcgcaugug      120

ucgccguuua caaggacggu agagcgggag ugguagcuaa cgaugccggc gacaggguga      180

cacccgcagu cguggccuau uccgagaaug aagagauugu ugggcucgcu gcaaaacagu      240

cucggauacg caacaucuca aauacuguga ugaaggucaa acaaauucuu ggacgaagua      300

gcuccgaucc ucaggcccag aaguacaucg cugaaucuaa augccuggug auugagaaga      360

acggcaaguu gcguuaugaa aucgacacgg gugaggagac caaauucgua aauccagaag      420

auguugccag auuaauauuu ucgaagauga aagagacagc gcauucagug cuggggagcg      480

acgcaaacga ugucgugauc acugugccgu ucgacuuugg agaaaagcag aaaaaugccc      540

uaggcgaggc ugccagggca gcuggcuuca acguccuccg gcugauucac gagcccagug      600

ccgcgcuucu ggccuacggg aucggacaag auuccccuac cgguaagucu aauauuuugg      660

uuuuuaagcu cggcgggaca agccuguccc ugucagugau ggaaguaaac aguggaaucu      720

aucgcgugcu cagcaccaau acugacgaua acauaggcgg ugcacauuuc acagagaccu      780

uagcucagua ccuggccucu gaauuucaga gauccuucaa acacgacguc agggggaaug      840

cucgggccau gaugaagcug acgaacucag cagagguggc caaacauagc uugaguacuc      900

ugggaucugc uaauuguuuu cuagauuccc ucuaugaagg ccaggacuuc gacugcaacg      960

uuagccgcgc gcgauuugag cugcuuuguu cgccacuguu caacaagugc auugaggcaa     1020

ucagaggcuu gcucgaucaa aauggguuua ccgccgacga uauuaacaaa gugguccugu     1080

guggagguuc uuccaggauc cccaaguuac agcagcugau caaagaccuc uucccugcug     1140

uggaacuucu uaauucaauu ccacccgaug agguaauacc uaucggcgcc gcaauugaag     1200

ccgggaucuu gauaggaaag gagaaccuac ugguugaaga cagucucaug auugagugca     1260

gcgcucggga uauccuggug aagggcgucg acgaguccgg ugccucucgu uucacagugc     1320

uuuuuccaag cgggacuccg cugcccgcac gcagacagca caccuugcaa gcgccuggcu     1380

caaucaguuc cgucugucuc gaacuguacg agagcgaugg caaaaauucu gcuaaggaag     1440

agacaaaauu cgcccaggug guuuuacagg accuggauaa gaaagaaaac ggacuaaggg     1500

acauucucgc agugcugacc augaagcggg acgggucacu ucacguaacg ugcacugauc     1560

aagagacagg aaagugugag gccaucagua uugaaauagc uagcugagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  4147
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt3)

<400>  4147
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gccuggacgu ugggucccag ucuugcuaca      120

ucgccguggc uagagcagga gguauugaga ccauagccaa cgaguucuca gauaggugua      180

cacccagugu aaucagcuuu ggcuccaaga aucggacuau ugggguggcg gcuaaaaacc      240

aacagaucac gcacgccaau aacaccgucu cuaauuucaa gcgcuuucau ggacgagcau      300

ucaacgaccc uuuuauucag aaagagaagg aaaaucucuc guaugaucuu gugccacuga      360

aaaacggcgg uguugggauc aaggugaugu acaugggaga ggaacacuug uucucagucg      420

agcagauaac agccauguua cugacuaagc uaaaagagac cgcugaaaau agccucaaga      480

aaccggugac agacugcgua aucaguguuc ccuccuuuuu caccgaugca gagcguagau      540

cugugcugga cgccgcucaa auugucggcc uuaacugucu gagguugaug aaugauauga      600

cugccguggc gcucaacuau ggcaucuaca agcaggaccu gccuagccug gaugaaaaac      660

cacggauugu ggucuuuguu gacauggggc auuccgcauu ccagguguca gccugcgcuu      720

uuaauaaggg aaagcucaaa guauuaggua cagccuucga ucccuuucug ggcgggaaga      780

acuucgacga gaaacuugug gagcacuucu gugcagaauu uaagaccaaa uauaaguugg      840

augcuaaaag uaagauccgc gcccugcuaa gacucuacca ggagugcgaa aagcugaaaa      900

agcugaugag cucuaauucc acggaccuuc cuuugaacau agaguguuuc augaacgaca      960

aagaugucuc aggaaagaug aauaggagcc aauuugaaga acucugcgcg gagcuguuac     1020

agaaaauuga agugccacug uauagucucc uugagcagac ucaucugaag guugaagacg     1080

ugucugccgu cgagaucgug ggcggugcaa cccggauucc cgcuguaaag gaacgcaucg     1140

ccaaauucuu ugggaaggau aucuccacaa cuuugaacgc ugacgaggcc guugcacgag     1200

gaugugcccu acagugcgcu auucugagcc cugcguucaa agugagagag uuuucgguca     1260

ccgaugcagu gccauucccg auaucucuca ucuggaauca cgacuccgaa gauacagagg     1320

gcguccacga aguguuuuca aggaaccaug ccgcucccuu caguaagguu cugaccuuuc     1380

uucggcgugg cccuuucgag cuggaagccu uuuacagcga cccacaaggg gugcccuacc     1440

cugaggcaaa aauuggacgc uucguagucc agaauguguc cgcccagaag gauggugaga     1500

agucuagagu uaaagugaag gucaggguga acacgcacgg caucuucacu auaagcacag     1560

cuucaauggu agaaaaagug ccaaccgagg aaaaugagau gaguuccgag gccgacaugg     1620

aauguuugaa ccaacggccc ccggagaauc cugauacuga caagaacguu cagcaggaca     1680

auagcgaagc agggacacag ccccaagucc agaccgaugc gcagcagacg ucucaaucac     1740

caccuagucc cgagcucacc agcgaagaga acaaaauucc agacgcugau aaggccaaug     1800

agaagaaagu ggaccagccc ccugaagcaa agaaaccaaa gaucaaagug gucaacguug     1860

agcugccgau cgaagccaau uuaguguggc agcugggaaa ggaucuacuc aacauguaua     1920

uugagacaga aggcaaaaug aucaugcagg acaagcugga gaaggagcga aacgaugcua     1980

aaaaugccgu ggaagaguac guauaugaau uucgcgacaa acuuugcggu cccuacgaga     2040

aauucauuug cgaacaagau caucagaacu uuuugagacu gcucacugag accgaggacu     2100

ggcuguauga agagggggaa gaucaggcaa agcaggcuua cgucgacaaa cuugaggagc     2160

ugaugaagau aggcacaccu gugaagguua gguuccaaga agccgaggaa cggccaaaaa     2220

uguuugagga auugggacag cgccuccagc acuaugcgaa gaucgccgcu gauuucagaa     2280

auaaagacga gaaguacaac cacauugacg aguccgaaau gaaaaaggug gagaagucug     2340

ucaaugaagu gauggagugg augaacaaug uuaugaacgc acaagccaaa aagucgcugg     2400

aucaggaccc cgugguaagg gcucaggaaa ucaaaacuaa gaucaaagag uuaaauaaca     2460

ccugugagcc ugucgugaca cagccaaagc ccaagauuga aagcccgaaa cuggagcgua     2520

ccccuaaugg cccaaacaua gauaagaaag aagaggaccu agaagauaag aauaacuuug     2580

gggccgagcc cccucaucaa aauggagagu gcuaccccaa cgaaaagaac uccgugaaua     2640

uggaccucga uugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  4148
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt3)

<400>  4148
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg ugagaaggca gcggccccgc cgacgugucu      120

gcugggcucu gguugcagug cuccuugccg aucuguuggc guuaagcgac acccuggcug      180

uaauguccgu ggaucuaggc ucugagucaa ugaaagucgc caucgugaag ccugggguuc      240

caauggaaau ugugcucaac aaagagagua gaaggaagac accggucaua gugacucuga      300

aagaaaauga gcgguucuuu ggagacagcg cagccuccau ggcuaucaag aaccccaagg      360

caacgcuucg cuacuuccaa caccuguugg guaaacaggc cgauaauccu cauguagcuc      420

ucuaucaggc cagauuucca gaacacgagc ugaccuucga cccccagagg caaacaguuc      480

auuuucagau uucuucgcag cugcaguucu caccugagga agugcucggc auggucuuaa      540

acuacagccg gagucuggcg gaggauuuug cagaacaacc aaucaaggac gccgugauua      600

cugugcccgu cuucuuuaau caggcugagc gccgagccgu ucuucaggca gcuagaaugg      660

ccggguugaa agugcugcag cuaaucaacg auaauaccgc gacagcccuc uccuauggag      720

uauucaggcg gaaggacaua aacaccacug cacaaaauau cauguuuuac gauaugggcu      780

cugguagcac aguguguacc auugucacgu aucagauggu gaaaacuaag gaggcuggga      840

ugcagccuca acugcagauc cguggaguug gcuucgaccg cacccuuggc gggcuggaaa      900

uggaguugag acucagggaa cggcuggccg gauuauuuaa cgagcagcga aagggucagc      960

gcgcuaaaga ugugagagaa aauccaaggg ccauggcaaa gcugcuccgg gaggccaacc     1020

gccuuaaaac aguccugucc gcuaaugcgg accacauggc acaaauugag ggcuugaugg     1080

acgaugugga cuucaaggcc aaaguaacua gaguugaguu cgaggaacua ugcgcugauc     1140

uguuugagag ggugccgggg cccguccagc aggcccucca gucagcagaa augagucugg     1200

acgagaucga gcaagugaua cuugucggag gcgccacccg ugugccucgg guucaggaag     1260

ugcuguugaa ggcuguaggu aaagaggaac ucgggaagaa cauuaaugcc gaugaggcag     1320

cggcuauggg agccgucuac caggcagccg cucugagcaa ggccuucaaa gugaagccau     1380

uuguugugcg agacgcaguc guguauccca ucuuaguaga guucacaaga gagguggagg     1440

aagaaccugg cauucauucu cugaaacaca acaagagggu ucuauuuucc cgcaugggcc     1500

cauaccccca gcggaaaguc aucaccuuca acagauacuc acacgauuuu aauuuccaua     1560

ucaacuaugg ggaccucgga uuucuggguc cggaagaucu uaggguguuc ggcagccaaa     1620

auuugacgac ugugaagcug aagggggucg gagacaguuu uaaaaaguac ccugauuaug     1680

agucuaaagg cauuaaggcu cacuucaacc ucgacgaguc cgguguucug agccuugacc     1740

gcguggaauc gguguuugag acacugguag aagauucugc cgaggaagag uccaccuuga     1800

cuaaacucgg gaauacaaua ucaagucugu ucggcggagg caccacgccc gacgcgaagg     1860

agaacgggac cgauacaguc caggaagagg aagagagccc agccgaagga uccaaggacg     1920

agccugguga acagguggaa uuaaaagagg aagcugaggc acccguugaa gauggcucuc     1980

agccaccccc uccagagccg aagggggacg ccacucccga gggagaaaaa gcuaccgaga     2040

aggaaaaugg cgauaaaagc gaggcccaaa agccuucaga gaaggcagaa gcggguccag     2100

aggggguggc ccccgcuccu gaaggcgaga aaaagcagaa accagcccga aagcggcgua     2160

uggucgaaga gaucggagug gagcugguug ugcuagaccu ccccgaucug ccggaagaca     2220

aacuugcaca gaguguacaa aaguugcagg aucugacacu cagagaccug gagaaacagg     2280

aaagggagaa ggcugccaac uccuuagaag cauucauuuu ugagacucag gauaagcugu     2340

accaaccuga guaucaggaa gucagcaccg aggaacagcg cgaggaaauc ucuggcaaac     2400

uuucagccgc uaguacaugg uuggaggacg aggggguggg agcgaccacu gugaugcuca     2460

aggaaaaacu ggccgagcua cggaagcugu gucagggucu cuucuuuaga gucgaagaga     2520

ggaaaaagug gccagagcga cugagcgcac uugacaauuu gcugaaccau uccucuaugu     2580

ucuuaaaggg cgcucgccuc auacccgaaa uggaucaaau uuuuacggag guugaaauga     2640

caacccugga gaaagugauc aaugaaacuu gggccuggaa gaacgccacc cuugcugagc     2700

aggcaaaacu gccugccaca gagaagcccg uauugcucuc gaaagacauc gaagcgaaga     2760

ugauggcucu ggaucgggag gugcaguacc uacugaauaa ggccaaauuc accaagccaa     2820

gaccuaggcc caaagacaag aacgggacuc gugcagaacc accgcucaau gccagcgcuu     2880

ccgaucaggg agagaaaguc auuccucccg caggccaaac agaagacgcc gagccaaucu     2940

cagagcccga aaagguggag acggguagug aaccugggga uaccgagcca cuggaacuug     3000

gcggacccgg cgcggagccu gagcagaagg aacagucuac ugggcaaaaa cgcccguuga     3060

agaacgacga gcugugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4149
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt3)

<400>  4149
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaaa cccagacaca agaccagccu auggaggaag      120

aggaagugga gacuuucgcc uuucaggcug agaucgcaca gcugaugagc cucauuauaa      180

acacguucua cuccaauaag gaaaucuuuc uuagagagcu gauuucuaac ucaagugaug      240

ccuuggacaa aaucagguau gagagcuuaa ccgauccauc caagcuggac ucuggcaaag      300

agcuacacau uaaucucauc ccgaacaagc aagaucggac acugacuaua gucgacaccg      360

ggaucggaau gacaaaagcg gaucuuauua auaaccuggg uaccaucgcu aagucgggca      420

cuaaggccuu cauggaggca uugcaggccg gggcugacau uucaaugauc ggacaguuug      480

gcguugguuu cuacagcgca uaucucgugg ccgaaaaagu aacagugaua accaagcaua      540

augaugacga gcaguacgcu ugggaaaguu ccgccggggg aucuuuuacg guccgcacug      600

auaccggcga gcccaugggc cgagggacaa aagugauucu gcaccugaag gaagaccaaa      660

cugaguaucu cgaggaacgu agaaucaaag agauuguuaa gaagcauagc caguucaucg      720

gauacccuau caccuuauuu guggaaaaag agagggauaa ggaagucucc gacgacgagg      780

cggaggaaaa agaggauaag gaagaggaaa aagagaagga ggaaaaagag ucagaagaca      840

agccagagau ugaggaugug gguagugacg aagaggaaga gaagaaagau ggcgacaaga      900

aaaagaaaaa gaagauaaaa gaaaaguaua ucgaucagga ggagcugaac aaaacaaagc      960

ccauuuggac ccggaauccu gacgauauca cgaacgaaga guacggggag uucuacaaaa     1020

gccuuacuaa ugacugggaa gaucacuugg caguaaagca uuuuucuguu gaaggacagc     1080

uggaguuccg cgcccuacuc uuugugccaa gaagggcucc cuucgaccug uucgagaacc     1140

ggaagaaaaa gaauaacaua aaacuuuaug uccgccgagu guuuauuaug gacaauugcg     1200

aagaacugau cccugaauac uugaacuuca ucagaggcgu ggucgauucc gaggaccucc     1260

cacugaacau uucaagggaa auguuacaac agagcaagau ccugaaaguu auucggaaga     1320

aucucgugaa gaaaugucuu gagcuguuua cagaguuggc cgaagauaag gagaacuaua     1380

aaaaguucua cgaacaguuu aguaaaaaua uaaagcuagg uauccacgag gacucucaaa     1440

accguaaaaa gcuguccgag cuccugcgcu auuacaccag cgcaucgggg gaugaaaugg     1500

uaucucuuaa ggacuauugc acuagaauga aagagaauca gaagcacauu uacuacauca     1560

caggagaaac caaagaucag guggcuaacu ccgccuucgu cgagaggcug cggaagcaug     1620

gcuuggaagu gaucuauaug auugagccga uagacgagua cuguguucag caacucaaag     1680

aauuugaggg caagacgcug gugucaguca ccaaggaagg guuagagcug cccgaagaug     1740

aggaggagaa aaagaaacag gaagaaaaga aaacaaaguu cgagaaucua ugcaagauca     1800

ugaaagacau ucucgaaaag aaaguggaga agguaguugu gaguaaccga cuggucacua     1860

gcccuuguug caucgugacc uccacauaug gauggacugc gaauauggag cgcauuauga     1920

aagcccaggc acuuagagau aacucuacca uggguuacau ggcugccaag aagcacuugg     1980

aaaucaaucc agaccauagc auaaucgaga cacugaggca gaaagcugaa gccgauaaga     2040

acgacaaauc agucaaggac cucgugauuc ugcuuuauga gaccgcacug uugaguuccg     2100

gcuuuagccu cgaggauccc caaacucacg ccaaucggau cuaccgcaug auuaaacugg     2160

gguuaggaau cgacgaagau gacccuacgg cugaugacac aucugcggca guuaccgagg     2220

aaaugccacc ccuggagggc gaugacgaua cuucaagaau ggaagaggug gacugaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  4150
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt3)

<400>  4150
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucca agcuggauuc uggcaaaggg cuccacauca      120

accuugugcc caauaagcag aaccaaaccc ugacaauugu cgacacuaga auaggaauga      180

cgaaaaccga uuugaucaau aacuuaggua caguuacuaa gucaggcacc aaagccuuca      240

uggaggcucu gcaggcagac gccgauauua guaugaucgg gcauuuugga gugggcuucu      300

acagcgcgua ucuaguagcu aagaagguga cagucauuuc caaacacaau aacgacgaac      360

aguacaccug ggagucuucg gccggugggu cauuuacugu gaggacagau gaaugaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  4151
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt3)

<400>  4151
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaag ugcaccaugg cgaggaagag gucgaaaccu      120

ucgccuuuca ggcugagauc gcacaacuga ugagccucau uauaaacaca uucuacucca      180

auaaggagau cuuucuuaga gaacugauuu cuaacgccuc agacgcguug gauaaaauca      240

gguaugagag uuuaacugac ccuagcaagc uggauuccgg gaaagaacua aagauugaca      300

ucauaccaaa uccgcaggag cggacgcuca cccugguuga uacaggaauc gguaugacua      360

aagcugaccu uauuaacaau cugggcacca ucgccaaguc ugggacaaag gcauucaugg      420

aggccuugca ggcuggagca gauauuucga ugaucggcca guuuggugug ggguucuacu      480

cagccuaucu cguagcugaa aaaguggucg ugauaaccaa gcacaacgac gaugagcaau      540

acgccuggga aagcagugcg ggaggcuccu uuacuguucg cgcagaccau ggcgagccca      600

uugggcgagg aacaaaagug auccugcacc ugaaggaaga ucagaccgag uaucucgagg      660

aacguagagu caaagaggug guaaagaagc auucucaguu cauugguuac ccuaucacgu      720

uauaucugga aaaagagagg gaaaaggaga ucagcgacga ugaggccgaa gaggaaaaag      780

gcgagaagga agaggaggac aaagacgaug aagagaagcc aaaaauugaa gacguugggu      840

ccgaugagga ggacgauuca ggaaaggaca agaaaaagaa aacuaagaaa auaaaggaaa      900

aguacaucga ucaggaggaa cuuaauaaaa ccaagcccau uuggacacgg aacccugacg      960

auaucacuca agaggaauac ggcgaguuuu auaaaaguuu gaccaaugac ugggaggauc     1020

accuggcugu gaagcacuuc agcgucgaag gucagcuaga guuucgcgcc cuccuguuca     1080

uaccaagaag ggcacccuuu gaccuuuucg aaaacaaaaa gaagaaaaau aacauuaagc     1140

uguacgugcg gcgcguguuc aucauggacu cuugcgauga guugaucccu gaauaucuca     1200

auuuuauucg aggggucguu gacuccgagg aucugccauu aaacaucuca agagagaugc     1260

ugcagcagag caaaauucuc aaggugauaa ggaaaaauau cguaaagaag ugucuugaac     1320

uguucaguga guuggcugaa gacaaagaga acuacaagaa auuuuaugaa gccuucucua     1380

agaaccuaaa acugggcauu caugaggauu ccacaaaucg gcgucgccuc agcgagcugc     1440

uuagauacca caccucgcaa ucuggagacg aaaugacguc ccugucagag uaugugagua     1500

ggaugaagga aacucagaaa agcaucuacu acaucacagg cgaguccaag gagcaggucg     1560

cgaacucugc cuuuguggaa cggguucgaa agcgcggguu cgaggugguc uauaugaccg     1620

aaccgauuga ugaguacugc gugcaacagu ugaaagaauu ugacggaaag agccucguau     1680

caguuacuaa agagggucug gaguuacccg aagaugagga agagaagaaa aagauggaag     1740

agaguaaggc aaaauucgag aaucugugua agcuaaugaa agaaauacuc gacaagaaag     1800

uggagaaggu cacaaucucc aacagacugg ugagcucucc uugcuguauu gucaccucaa     1860

cguauggcug gaccgcuaau auggaaagga ucaugaaggc ccaggcccuu cgggauaaca     1920

guacaauggg guacaugaug gcuaaaaagc auuuggagau uaauccagac caccccaucg     1980

uggaaacucu gcgccagaaa gcagaggccg auaagaacga caaagcuguu aaggaccucg     2040

ugguacugcu uuuugagacc gcgcuguuga gcuccggauu cucucucgaa gauccucaaa     2100

cacacucgaa uagaauauau aggaugauca agcugggcuu agguauugac gaggaugaag     2160

ucgcagccga ggagccaaac gcugccgugc ccgacgaaau cccgccucug gagggggaug     2220

aagacgcaag ccguauggag gaaguugauu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  4152
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt3)

<400>  4152
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agagcccugu gggugcucgg ccuuugcugu guccuguuga      120

ccuucgggag cguuagggcu gacgaugagg uggacguaga uggaacagug gaagaggacu      180

uagguaaguc ccgggaaggc ucucgcacug augacgaggu cgugcagcga gaagaggagg      240

caauccaacu ggaugggcua aacgccucac agauucguga acucagagag aaaagugaaa      300

aguuugcguu ccaggcugag guuaauagga ugaugaaacu gauaaucaac agccuuuaca      360

agaauaaaga gauuuuucug cgggaauuga ucuccaacgc cucugacgca cucgauaaga      420

uucgccugau cucgcugacg gacgagaaug cccucucagg aaacgaagag uuaaccguga      480

agauaaaaug cgauaaggag aaaaaucugc uucacgucac agacacuggc guggguauga      540

ccagagagga guugguaaag aaccugggga caaucgcuaa aagcggaacc agugaguucc      600

uaaauaagau gacugaagca caggaagaug gccaauccac aucugagcuc auuggccagu      660

uugggguugg auucuauagc gccuuucugg uggcugacaa ggucaucgug accuccaaac      720

auaacaauga cacgcagcac auuugggaau cagauaguaa cgaguucagc gugaucgccg      780

accccagggg uaauacucuu ggccggggga ccacaauaac ucuggucuug aaggaggaag      840

cgucugauua ccucgagcug gacaccauua aaaacuuagu uaagaaauau ucccaguuua      900

ucaauuuccc uauuuacgug uggucaagca agacagaaac cguagaggaa ccaauggagg      960

aggaagaggc agccaaagaa gagaaggagg aaagugauga cgaggcugcc guggaagagg     1020

aagaggagga aaagaaaccg aagacgaaaa aggucgagaa aacugugugg gauugggaac     1080

ugaugaacga caucaagccc aucuggcaac gcccuucuaa ggagguugaa gaggaugagu     1140

auaaagcauu uuacaagucc uucagcaaag aaucggacga uccaauggcu uauauucauu     1200

uuacagccga gggagaagug accuucaagu cuauacucuu cguccccacu uccgcgccuc     1260

gaggccuuuu ugacgaguac gguaguaaaa agucagacua caucaagcug uaugugagaa     1320

ggguauucau uacagaugac uuucacgaua ugaugccaaa auacuugaac uucguuaagg     1380

ggguggucga cagcgaugac cuaccccuga augugucccg ggaaacccuc cagcagcaua     1440

aacugcuuaa ggucauccgu aaaaagcugg ugcgcaagac guuggauaug auuaaaaaga     1500

uagccgacga uaaauauaac gacaccuuuu ggaaggaguu cggaacaaau aucaaacucg     1560

gcguuaucga ggaucacucu aacagaacua ggcuggcaaa guuacugcgg uuucagagcu     1620

cacaccaucc uaccgacauu acaagucuag aucaauacgu ggaacgaaug aaagagaagc     1680

aggacaagau cuauuucaug gcuggcucca gccgcaaaga agccgagucu ucaccauuug     1740

uagagagacu ccugaagaaa ggguacgaag ucauuuaucu uacugagccg guggacgaau     1800

acuguauaca ggcuuugccc gaguucgaug gaaagagguu ucaaaauguu gccaaagaag     1860

gugugaaguu cgacgagagu gagaagacca aagaaagccg ggaggcaguc gaaaaggagu     1920

uugaaccucu gcucaacugg augaaagaua aggcccugaa agacaagauc gagaaggcug     1980

ugguauccca gcgccuuaca gagucuccau gcgcgcuggu ggcaucgcag uacggcugga     2040

gcgggaauau ggaaagaauu augaaagccc aggcuuauca aaccggaaag gauaucucca     2100

cuaacuacua ugccucacag aaaaagacgu ucgagaucaa ucccaggcac ccuuugauuc     2160

gugacaugcu ccggcgaaua aaagaagaug aggacgauaa gacaguucug gacuuagcag     2220

ucgugcuguu cgaaaccgcc acucuaagaa guggcuaccu ccugccagau accaaggcuu     2280

auggugacag gaucgagcgc augcuucggu ugucucugaa cauugauccc gacgccaaag     2340

uggaggaaga accggaagag gagccugaag agacagcaga agacaccacu gaggauacag     2400

aacaggacga ggaugaggaa auggacgucg ggacggauga ggaagaggaa accgcgaagg     2460

agagcacugc ugagaaagac gaacucugag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  4153
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt3)

<400>  4153
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagagagc ugagggcucu ccuucugugg ggccggcgcu      120

ugcgacccuu acugcgugcu ccugcccuag cggcugugcc agggggaaag ccgauccucu      180

gccccagaag gaccacagcc cagcuggguc cucggcgcaa cccagcaugg agccuucaag      240

ccggcagacu guucuccacu cagacggcug aagacaaaga ggaacccuug cacucuauua      300

uaucaaguac cgagagcguc caggggucca caucuaagca ugaauuucag gcagagacua      360

aaaagcuccu ggauaucguu gccaggucgc uguacucaga gaaagaagug uucauucggg      420

agcucaucag caaugcuagu gacgccuuag aaaagcugcg ccacaagcua guauccgaug      480

gacaagcguu gccugagaug gagauucauc ugcagaccaa cgcagaaaaa ggcacaauca      540

ccauacagga cacugguauc gggaugacac aggaggaacu ugugucuaau cucggaacca      600

uugcccgaag cggcuccaag gcuuuucugg augcccuuca aaaccaggca gaggcuucaa      660

guaaaaucau uggccaguuc ggggucggau uuuauagcgc cuucauggug gcggacagag      720

uugaagugua cucuaggucc gccgcaccag guucacuggg cuaucagugg uugagcgaug      780

ggaguggagu cuuugagauc gcugaggccu cuggcgugcg gacggguacu aagauaauua      840

uccaccucaa auccgacugu aaggaauuua gcucggaggc ucguguacgc gauguuguga      900

ccaaguacuc uaauuuuguc uccuuccccc uguauuuaaa cgggagaagg augaauacac      960

ugcaagccau uuggaugaug gacccuaaag augugcggga auggcagcau gaggaauuuu     1020

accgauaugu ggcacaggcc cacgacaagc cacgcuacac ucuccacuac aaaaccgaug     1080

cuccgcuuaa caucagauca aucuucuaug uccccgacau gaagccuagu auguuugacg     1140

uuagcaggga gcugggaucc ucuguggcgu uguacagccg gaaaguacua auucaaacaa     1200

aggcaaccga uauacugcca aaauggcucc gcuucaucag aggcgugguc gacucagagg     1260

auauuccccu gaaucuuagu agggaacugu ugcaggaguc cgcccucauc cguaagcugc     1320

gggacguguu acagcagcga cugauaaagu ucuuuauuga ucaaagcaaa aaggacgcug     1380

aaaaauaugc caaguucuuu gaggauuacg gccuauucau gagagaaggg aucguuacgg     1440

caacugagca ggaggugaaa gaagacaucg ccaagcuccu gagguaugag ucuucagcac     1500

uuccuagugg acaguugaca agccuguccg aauacgccuc ucgcaugcgg gcagguacca     1560

gaaacauuua uuaccucugc gcgccaaaua ggcaucuggc ugagcacucg cccuacuaug     1620

aggccaugaa gaaaaaggau acugaagucc uuuucuguuu cgagcaguuu gacgaacuga     1680

cauugcucca ucugcgcgag uucgauaaaa agaaauuaau cagcguggaa accgacauug     1740

uaguugacca cuacaaggag gagaaguuug aagaucgauc cccggcagcc gagugccugu     1800

cagaaaaaga gacggaagaa cuaauggcuu ggaugcggaa cgugcucggc agucguguca     1860

ccaaugugaa ggucacacug agacuugaca cucacccugc cauggugacc guuuuggaga     1920

ugggggcagc uaggcauuuc cugcgcaugc aacagcucgc caaaacacag gaggagcggg     1980

cgcagcuguu acaacccacu cuggaaauaa acccaagaca cgcccuuauc aagaaauuga     2040

aucagcucag ggcuucugag ccuggacugg cacagcuacu gguggaucag auuuaugaaa     2100

acgccaugau cgcugccggc cucguagacg auccccgagc aauggucggu cgccugaacg     2160

agcuuuuggu gaaggcgcug gagcggcauu gaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  4154
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt3)

<400>  4154
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagauca gcucccugcc cacccaacuc uucaaaugcu      120

guuuuugcga cuuccuuaag gugaaaaugc acacaauguc uucaagucau cuguuuuacu      180

uggccuuaug ucugcuaacu uucacgagcu ccgcuaccgc agggccugag acacucugcg      240

gagccgaacu ggucgaugcg cuucaguuug uuugugguga cagaggcuuc uauuuuaaca      300

agccaacugg guacggaucu ucgucaaggc gggcuccgca gaccggcauu guggaugagu      360

gcuguuuccg cagcugcgac cugcgacguu uggaaaugua uugugcaccc cucaaaccug      420

ccaagagugc cagauccgua agggcucagc ggcacacaga uaugccaaag acccagaaag      480

aggugcaucu gaagaaugca ucucgcggua gcgccgggaa caaaaauuac agaaugugag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  4155
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt3)

<400>  4155
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca ugggaaagag caugcuggug cuccuuaccu      120

uccuggccuu ugcuuccugc uguauugcag ccuacagacc uucugagaca uugugcgggg      180

gugaauuagu cgacacucug caguucguuu guggcgauag gggguuuuau uucucacggc      240

cagcgagucg cgugagccga cguuccagag gaauaguaga ggaaugcugu uuuaggucuu      300

gcgaccuagc ucuccuggag acguacugug ccaccccggc aaaaucggaa cgggaugugu      360

caacaccccc uacuguccuu ccagacaacu ucccccgcua uccugugggc aaguuuuucc      420

aauacgauac cuggaaacag agcacacaga gacugaggcg ggguuugcca gcccuccugc      480

gcgcucgaag agggcacguu cuggcaaagg agcucgaggc cuuuagggaa gcuaaacggc      540

aucgucccuu aaucgcccug ccuacccagg acccagcgca cggaggcgca ccgcccgaga      600

uggccaguaa ucgcaaguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  4156
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt3)

<400>  4156
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagcuucu ccaccucugc cuuuggcccc guggcuuucu      120

cacuggggcu ccuucugguc uugccugcag ccuuuccagc gccgguuccc ccuggagagg      180

acaguaagga uguggcugcc ccacacagac agcccuuaac aagcuccgaa aggaucgaca      240

aacaaauucg guacauacug gaugguaucu cugcacuacg caaggagacu ugcaauaaau      300

cgaacaugug ugaaucaagc aaggaggccc ucgcugaaaa uaaccugaau cuuccuaaaa      360

uggcagagaa ggacggcugc uuccagagug gguuuaacga ggaaacgugu cugguaaaga      420

uuaucaccgg auugcucgag uucgaagugu aucuggagua ccugcagaau cgauuugagu      480

ccucugaaga acaggcccgu gcuguccaaa ugagcacaaa agugcucauu caguucuuac      540

agaagaaagc caagaaccug gaugcgauca cuaccccaga ccccacaacc aaugcauccc      600

uuuugacuaa acugcaggcc caaaaccagu ggcuacagga uaugacaacc caucucauac      660

ugagaucauu uaaggaguuc cuucagagua gccugagggc uuugcggcaa augugaggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  4157
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt3)

<400>  4157
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcucu ggcuuagagg cuuccuguug gccagcugcu      120

ggaucauugu gagguccucu ccuaccccag ggucagaggg acacagugcu gcaccggacu      180

gucccagcug cgccuuagcg gcucugccua aggauguccc aaacucccag cccgaaaugg      240

uugaggccgu gaaaaagcau auacuaaaua ugcuccaccu gaaaaagcgg ccugacguaa      300

cacaaccagu gcccaaagca gcccuucuga acgcuauccg caaguugcau gucgguaagg      360

ugggcgaaaa uggguacguu gagauugaag augacaucgg acgacgugca gagaugaacg      420

agcucaugga acagacuucu gagauuauca cguuugccga aucgggcacc gcuagaaaaa      480

cacugcacuu cgagauauca aaggagggua gcgaucugag uguggucgaa agggccgagg      540

uguggcucuu uuuaaaagua ccuaaggcga aucggacucg caccaaaguu acaaucagac      600

uguuccagca gcaaaagcau ccacaggggu cccuugacac cggagaagag gcagaagagg      660

ugggcuugaa gggcgagagg ucugaacugc uacucagcga gaaagucgug gaugcccgga      720

aguccacuug gcacguguuu ccggucucaa guagcauuca gcgccugcuu gaccagggga      780

aaucuucccu ggauguucga aucgcuugug aacaaugcca ggagucagga gccagcuugg      840

ugcuccuggg uaagaaaaag aaaaaggaag aggagggcga agggaagaaa aagggaggcg      900

gugaaggggg agcaggcgcu gacgaggaga aagaacagag ucacagaccc uucuuaaugc      960

ugcaggccag gcaaucugag gaucauccuc accggcgucg cagaaggggc cucgagugug     1020

acgggaaggu aaacauuugc uguaaaaagc aguuuuucgu guccuuuaag gauaucggau     1080

ggaaugacug gauaauugcg ccaagcgguu aucaugccaa cuacugcgaa ggcgaguguc     1140

ccucgcacau cgcagggaca ucuggauccu cacuuaguuu ccacagcacc gucauuaauc     1200

auuaucggau gcgaggccac uccccuuuug cuaaccugaa aucuugcugu gugccaacga     1260

aguugcgccc caugagcaug cuauacuaug acgaugguca gaauaucauc aaaaaggaca     1320

uucaaaacau gauaguugaa gagugcgggu gcucaugagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  4158
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt3)

<400>  4158
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccugc ccgggagagc ccucggagcu gcaugccuuc      120

uguuguuagc cgcggguugg cugggcccug aggcuugggg gagcccaacc ccgcccccua      180

caccagccgc acccccucca cccccuccac cgggaucccc cggcgguucu caggauacuu      240

guacgucaug cgggggauuc aggcggccug aggaacuagg ccgcguggac ggcgauuuuc      300

ucgaagccgu caagcgacac auccugaguc gucuucaaau gagagggagg ccaaacauua      360

cccaugcugu ucccaaagca gccaugguga cagcucugcg gaaguugcac gccggaaaag      420

uacgcgagga cgguagagug gaaauaccuc aucucgaugg ccacgcgagc ccaggggcag      480

acggacagga gagggucucc gagaucauuu cuuucgccga aacugauggc cuggcuucgu      540

cacgggugcg ccuguacuuu uucaucagca augaggguaa ccagaaucuc uuuguugugc      600

aggccaguuu auggcuguau cuuaaguugc ugcccuacgu ccuagaaaaa gggucccgaa      660

gaaaggugag gguaaagguu uauuuccaag agcagggaca uggcgaccgg uggaacaugg      720

uggagaaacg ugucgaucuc aagcgcucug gcuggcacac cuuuccgcug acagaagcaa      780

uucaggcucu uuucgagaga ggggaaaggc ggcugaauuu ggacgugcag ugugauagcu      840

gccaagagcu cgccgugguc ccuguuuuug uggaccccgg agaagagucc caccgaccau      900

ucguaguggu ccaggcgcgc cugggugauu caagacauag gauccggaaa cgcggcuuag      960

agugugacgg gagaaccaac cugugcugua ggcagcaguu uuucauagac uuucgucuca     1020

ucggauggaa ugauuggauu aucgccccua cuggcuacua ugguaacuac ugcgaaggga     1080

guugucccgc auaucuugcu ggcgugccag gaagcgccuc uuccuuccac acagcuguug     1140

ugaaucaaua ccggaugcga ggccugaacc ccgggaccgu caauucaugc uguauuccua     1200

cgaaguugag cacuaugagu augcuauacu ucgacgauga guauaacauc gugaaaagag     1260

acguaccaaa uaugauaguu gaagagugcg gaugcgccug aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  4159
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt3)

<400>  4159
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagag ugcuccuucu gaccgcuuug acauuaugcc      120

acggcuucaa ccuggacacu gagaaugcaa ugacguuuca ggaaaacgcc aggggguucg      180

gacaaagcgu cguucagcua caggguuccc gggugguagu gggcgcgccc caggagaucg      240

ucgcugccaa ucaacgcggg ucucucuacc agugugauua uucaaccgga aguugcgaac      300

cuauucgacu gcaagugcca guugaggcag ugaacaugag ccuuggccug uccuuggccg      360

cuacaacuuc uccgccccag cuccuggcau gugguccuac cguccaucaa acaugcucgg      420

aaaauaccua cgugaagggg cuguguuuuc ucuucggauc aaacuuacgu cagcagccac      480

agaaauuucc cgaggcccug agaggcugcc cucaagagga cagcgauaua gcuuuccuua      540

ucgacggcag uggguccauu aucccacacg auuuuaggcg gaugaaggag uucguaucua      600

cuguuaugga acaguugaaa aagagcaaaa cacuguuuuc ccuaaugcag uauucagaag      660

aguuccgcau ucauuuuacc uucaaggagu uucaaaauaa ccccaauccu agaagucucg      720

ugaagccaau cacgcagcug cuuggaagga cucacaccgc cacagguaua cggaaagucg      780

ugcgcgaacu guucaacauc acuaauggcg cgcgaaagaa cgcauucaaa auuuuggugg      840

ucaucaccga cggggagaag uuuggagauc cgcucggcua cgaagacguu auucccgagg      900

ccgauagaga aggugugauc agguauguaa uagggguggg agacgcuuuc cggagcgaga      960

aaucucguca ggagcugaau acaauugccu ccaagccucc acgcgaucau gucuuucagg     1020

ugaacaauuu cgaagcauua aagaccaucc aaaaccagcu gagagagaaa auuuuugcua     1080

ucgaaggcac gcagacuggc ucaagcaguu cuuucgagca cgaaaugucc caggaggggu     1140

uuagcgccgc gaucacaucg aacggacccc uccuuucuac cguugguucc uacgacuggg     1200

ccggcggggu guuccuguau acuucaaagg agaaaaguac auuuauuaau augaccaggg     1260

ucgauagcga caugaacgac gcauacuugg gauacgcugc cgcuauaauc cuacggaauc     1320

gagugcaauc ccugguacuc ggcgccccuc gcuaucagca cauuggucug guugcaaugu     1380

ucagacagaa cacggggaug ugggaaucua augccaacgu gaagggcacc cagaucggag     1440

cuuacuuugg cgcgagccuu uguucagucg auguggacag uaaugggucc acagaucugg     1500

ucuugauagg agcaccacau uauuacgagc aaacuagggg uggccaggug agcguuugcc     1560

cccucccgcg ggggcgcgcc agauggcagu gugacgcugu gcuguaugga gaacagggcc     1620

aaccuugggg uagguucggg gccgcauuaa ccguacuggg cgaugucaac ggagacaaac     1680

uaacagaugu ggccauuggc gcucccgggg aggaagacaa ucguggagcc guuuaccucu     1740

uucacgguac uucuggcuca gggaucaguc caagccauuc ccagcggauc gcaggaucua     1800

agcugucgcc ucgacuucag uauuucggcc agagcuuguc cggugggcag gaucugacca     1860

uggacggccu cguggaucug acagucggag cgcagggcca cgugcuucug uugagaucac     1920

agcccguacu cagggugaaa gcuauuaugg aguucaaccc acgcgagguu gcccggaaug     1980

ucuuugaaug caacgaccaa guggugaagg ggaaggaggc aggagaaguc agaguuuguc     2040

ugcacgugca gaaaaguacc agggaccgcu uacgagaggg ccagauccag ucugugguaa     2100

cuuacgaucu ggcccuagac agcggucggc cccauucccg ugcugucuuc aaugagacga     2160

agaacucaac aagaaggcaa acccaggugc ucgggcugac ucagaccugc gaaacacuua     2220

aauugcagcu gccuaauugc auugaggauc caguuagccc gauagugcuc cgccugaacu     2280

uuucuuuagu cggaaccccu cuguccgccu ucggcaaccu ucggccugug uuggcagaag     2340

acgcucaaag acucuuuacu gcccuguucc cauuugagaa gaauuguggu aacgauaaua     2400

ucugccagga cgaucuaagu auuacauuca gcuuuauguc ucuggacugu cucguugugg     2460

gcgggcccag ggaguucaac guaacgguca ccgugcgaaa ugauggagaa gacuccuacc     2520

gcacucaggu gacauuuuuc uuuccucugg aucuuucaua ucggaaaguc aguaccuugc     2580

aaaaccagag aagccagagg ucguggcguc uggcgugcga guccgccucu agcacagaag     2640

uuucaggcgc uuuaaagagu acuuccuguu cuaucaauca cccaaucuuc cccgagaaca     2700

gcgaagugac cuucaauauu acguuugacg uagauuccaa ggcaucacuc gggaacaaac     2760

ugcuucugaa ggccaaugug accagcgaga acaauaugcc gcgcacaaac aaaacugagu     2820

uccaguugga acucccuguc aaguacgcug uguauauggu ugugaccagu cauggagucu     2880

cuacaaaaua ccugaauuuu acugccuccg agaacaccag ccgggugaug caacaccagu     2940

aucagguuuc gaaccuaggc cagagaucac ugccaauauc ucucguguuc cugguccccg     3000

uaaggcuuaa ucaaacggug aucugggacc gaccucaggu uacauuuagu gaaaacuugu     3060

ccucuaccug ccauacuaag gagcggcugc ccagccacag cgacuucuua gcagaacucc     3120

gcaaggcgcc aguggucaau uguuccauug ccgugugcca gagaauccag ugugauauuc     3180

ccuuuuucgg uauccaagag gaauuuaacg cuacacugaa agggaaucuu ucauucgacu     3240

gguacauaaa gaccagucac aaccaucugc uaaucguaag cacugccgag auucucuuua     3300

augauucugu guucacccug uugcccggac agggcgcauu cgucaggucc cagacagaga     3360

cgaaaguuga accauuugag gugccgaacc cucugcccuu aaucgugggu ucaagugucg     3420

gcgggcuccu gcuucuggcu uugauuaccg ccgcacucua uaagcuggga uucuuuaaac     3480

ggcaguacaa ggacaugaug agcgaaggcg ggccacccgg agccgagccu caaugaggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  4160
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt3)

<400>  4160
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucagccuga agacccuccc cuuucuucug uuguuacacg      120

ugcagaucuc caaagccuuc ccugucucuu caaaggagaa aaacacaaag acuguucaag      180

acuaccugga aaaauuuuau cagcuaccaa guaaucagua ccagagcacg agaaagaacg      240

gcaccaaugu gauuguagag aagcucaaag aaaugcaaag guucuuuggg cugaacguga      300

caggaaagcc gaaugaggaa acucuugaua ugaugaaaaa gccccggugc ggugucccug      360

acuccggcgg guucaugcug accccaggaa accccaaaug ggagcgcaca aauuugaccu      420

aucgaauacg uaacuacacu ccucagcucu cugaggcuga aguggagaga gcaaucaagg      480

augccuuuga acuguggucg guugcgucac cacugauuuu cacaaggauc agccagggcg      540

aggcugacau uaauaucgcc uuuuaucagc gggaucaugg ugacaacagu cccuucgaug      600

ggccuaaugg aauacucgca cacgccuuuc aaccaggcca gggcaucggg ggagacgcuc      660

auuucgaugc agaggaaacc uggacgaaca cuuccgccaa uuacaacuua uuucuggugg      720

cugcccacga guucggucau ucucuuggcu uggcgcacag cuccgacccg ggggcacuga      780

uguaucccaa uuacgccuuc cgcgaaaccu caaacuacag ucuaccucag gaugacauug      840

auggaaucca ggcuauuuau ggccucagcu cuaacccaau ccaacccaca gguccuucca      900

cuccaaagcc cugugacccg ucacugaccu uugacgccau aacaacccuu agaggggaga      960

uucuguucuu uaaagauagg uacuucuggc ggcgccaccc ucaguugcag cgagucgaaa     1020

ugaauuuuau cagccucuuc uggcccaguc ugccaacggg cauucaagca gcuuaugagg     1080

acuuugauag agacuuaauc uuccuguuua agggaaacca guacugggcc cucucuggcu     1140

augauauccu ucagggguac ccuaaagaca uuuccaauua uggauucccc agcucggugc     1200

aggcgauaga ugccgcagua uuuuacaggu cuaagacuua cuucuuuguu aacgaccaau     1260

ucuggcggua ugauaaucag cgucaguuca uggagccagg uuaccccaaa uccaucucag     1320

gcgcuuuucc ugggauugaa aguaaggugg acgccgucuu ccagcaagag cacuuuuucc     1380

auguguuuag cggaccacgc uauuacgcuu ucgaucugau cgcccagaga gugacaaggg     1440

ucgcacgggg caacaaaugg uugaauugcc gauaugguug aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  4161
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt3)

<400>  4161
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguggc agccccucgu gcuuguccug uugguuuuag      120

gcugcuguuu cgccgcuccu agacaaaggc aguccacccu ggugcuauuu ccaggggacc      180

uccggacaaa ccugacugau cgccagcuug cagaggaaua ccuguaucga uacggauaua      240

cgcguguagc cgagaugaga ggugaaucua aaucauuggg cccggcgcuc cugcugcucc      300

agaaacaauu aagucugccc gagaccgggg aacuugacag cgcuacauug aaggccauga      360

ggacuccucg gugcggagug ccagaucugg gccgcuucca gaccuuugag ggugaccuaa      420

aauggcacca ucacaauauc acauacugga uucagaacua uuccgaggau cuccccagag      480

cagucauaga cgaugccuuc gcuagggcau uugcccugug gucugcugug accccucuua      540

cuuucacacg gguuuacucg cgcgacgccg auaucgugau ucaguuuggg gucgcggaac      600

auggagacgg cuauccauuc gauggcaagg acgggcuguu ggcacacgcc uuucccccug      660

gaccagguau ccaaggcgau gcucauuucg acgacgauga gcucugguca cuggggaaag      720

gagugguagu uccgacccga uuuggcaaug ccgacggugc agcuugucac uuccccuuua      780

uuuucgaagg gagaagcuac agugccugca cgacugaugg aagguccgac ggcuuaccuu      840

gguguucuac cacagcgaac uacgauacug acgaucgguu cggcuuuugc ccaagcgagc      900

gucuguauac ccaggacggg aaugccgaug gaaagcccug ucaguucccu uuuaucuucc      960

agggucaauc cuacucagca ugcacaaccg acggccgcag ugauggguau agauggugug     1020

cuacgacugc caacuacgac agggacaagc ucuuuggauu cugcccaaca cgggcugaua     1080

gcaccgugau gggcgguaau ucugccgggg agcuuugugu cuuucccuuc acuuuucugg     1140

gcaaagaaua uuccacaugc accucagagg gacgaggcga cgggcgcuug uggugcgcaa     1200

cgaccagcaa cuucgauagu gacaagaaau ggggauuuug uccggaucag gguuacucuc     1260

uauuccuggu ggccgcucac gaauuuggcc augcgcucgg gcuggaccac uccagcgugc     1320

cugaggcacu uauguauccc auguacagau ucacagaagg accaccucug cauaaggaug     1380

acgucaaugg cauaaggcac uuguacgguc cccggccaga gcccgagccu cgcccaccga     1440

cuaccacaac uccccagccu accgccccac ccacaguuug cccuaccggg ccacccacug     1500

ugcacccguc ggaaagaccu acggcuggcc caacaggacc cccuucugcc ggccccaccg     1560

ggccaccuac ugcaggaccc uccaccgcca caaccguacc acucucaccg guggaugacg     1620

cuuguaacgu caauaucuuc gaugccauug cagagaucgg uaaccaacug uauuuauuua     1680

aagacggcaa guacuggagg uucagugaag ggcguggaag ccggccucag ggccccuuuc     1740

ugauugcgga uaaguggcca gcucuacccc gaaaacucga cuccguguuc gaggaaagac     1800

ugucuaagaa auuguuuuuc uuuagcggua ggcagguuug gguguauacu ggggccucag     1860

uccuuggccc ucgccggcug gacaagcucg gacugggcgc agauguggcc cagguaacag     1920

gggcucuuag aaguggaagg ggcaaaaugc uguuguucuc cggucgccga cucuggcggu     1980

uugacguuaa ggcccaaaug guggauccac guagcgcauc ugaggucgac agaauguucc     2040

ccggggugcc ucuggauacg caugacgucu uucaguacag ggagaaggcu uauuucugcc     2100

aggaucgcuu uuacuggcgg gugucaagua gaagcgaauu aaaucagguu gaccaagugg     2160

gauauguaac cuacgauauc cugcaguguc cggaggacug aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  4162
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt3)

<400>  4162
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg ugcuggccgc uuuccucuuu cuuagcugga      120

cccauugcag agcacugccu uugccauccg ggggagacga ggaugacuua ucugaagagg      180

aucugcaguu cgccgaaagg uaccuacggu cauauuacca cccgacaaac cucgcgggua      240

uccugaagga gaaugcugcc aguagcauga cugaacgccu ucgagagaug caauccuuuu      300

ucggccugga ggucacgggg aaauuggacg auaacacccu cgacguuaug aagaaacccc      360

guuguggagu gccugaugua ggcgaauaua auguguuucc aagaacacug aaguggucua      420

aaaugaaccu gacuuacagg auugucaauu auacccccga caugacacau ucggaggugg      480

aaaaggcauu caagaaagcc uuuaagguuu ggucagaugu gaccccucuc aacuucacuc      540

gguuacacga cgguauagcu gauaucauga uuagcuuugg gaucaaagag cauggagacu      600

ucuacccauu ugauggcccc aguggccugc uugcacacgc cuucccucca gggccgaauu      660

auggagguga cgcucacuuu gacgaugacg agacauggac cuccucuagc aagggcuaca      720

acuuguuccu ggucgccgcg caugaguucg ggcacucccu aggacucgau cauucaaaag      780

accccggcgc acugauguuu ccuauuuaca cguauacugg uaagagucac uucaugcuuc      840

cagaugacga ugugcagggg auccagagcc uguacggacc cggcgacgaa gauccuaauc      900

caaagcaccc caaaaccccg gacaagugcg auccuucuuu gucccucgac gccauaacau      960

cacugcgcgg cgaaacuaug aucuuuaaag acagauucuu uuggagguua cauccccagc     1020

aaguagaugc ugagcuguuc cucaccaaga gcuuuuggcc agaacuuccu aaccggauug     1080

acgccgcaua ugagcacccc agucaugauc ugaucuucau uuuucgcggg cgaaaauucu     1140

gggcuuugaa uggauacgac auccuagagg guuauccaaa gaaaauaucu gaacugggcc     1200

uccccaagga gguuaagaaa auuuccgccg cggugcacuu ugaagauaca gggaagaccc     1260

ugcuuuucag cggaaaccag gucuggagau acgacgauac gaaucauauc auggacaaag     1320

auuauccuag gcugauugag gaagacuuuc caggcaucgg ugauaaggug gacgccgugu     1380

acgagaaaaa cggguacauc uauuucuuca auggcccgau ucaguuugag uacucgauau     1440

ggucuaaccg gaucguccgu guuaugcccg caaacuccau uuuguggugu ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4163
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt3)

<400>  4163
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acacaacuga agacuacgau acgaccacag      120

aguucgacua uggcgaugcc acuccuugcc agaaggugaa ugaaagagcu uuuggggcac      180

aacugcuccc accgcuuuac agccuggucu ucguuaucgg auuggugggu aacauuuuag      240

uagugcuggu ccuagugcag uauaaaaggc ucaagaauau gaccuccaua uaccugcuua      300

accuggccau cucugacuug cucuuucugu ucacacugcc cuuuuggauu gauuauaaac      360

ucaaggacga uuggguuuuc ggcgacgcga uguguaaaau cuuaucaggg uuuuacuaua      420

ccggacugua cagugagauu uucuuuauca uacuuuugac uaucgaucgg uaccuggcua      480

uugugcacgc cgucuucgca cuacgcgccc gaacagugac cuuuggcgua aucacgagca      540

uuaucauaug ggcucucgca auucuggccu ccaugccugg ucuuuauuuc ucuaagacuc      600

agugggaauu uacccaucac acaugcucgc ugcauuuccc acacgaguca uugcgugagu      660

ggaaacucuu ccaggcucug aaguuaaauc uguuugggcu cguucuuccc cuguugguga      720

ugaucauuug uuacacugga aucaucaaga uucuacugag aaggccuaac gagaaaaaga      780

gcaaagccgu ccggcucaua uucgugauca ugauuaucuu uuuccuguuu uggaccccau      840

auaaucuuac aauacugauu aguguguucc aagacuuuuu guucacccau gaaugcgaac      900

agucccgcca ccucgaucug gcgguccagg uuacggaggu gaucgcauac acucacuguu      960

gcguaaaccc cgugaucuau gccuuugucg gcgagagauu caggaaguac uuacggcagc     1020

uguuucaucg ccgaguggcu guucaccuag ugaaguggcu cccuuuccug ucugucgaca     1080

gacuugaaag ggugagcucc acaucaccaa guaccggcga gcaugaauug agcgccgggu     1140

uuugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  4164
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt3)

<400>  4164
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agaacccugg ccugccuccu ucuguuggga uguggguacu      120

uagcucacgu gcuggcagag gaagccgaga uccccaggga agucauugag cggcuagcgc      180

gcagccagau acauuccauc cgagaccucc aacgucugcu ugaaauugau ucuguuggau      240

cagaggacag ucuggauacu agcuugagag cucacggugu gcaugccaca aagcacguac      300

cugagaaaag gccacucccg auccggcgca agagauccau ugaagaggca gugcccgccg      360

ucugcaaaac gaggaccgug aucuaugaaa uaccucgguc ucagguugac ccaacaucgg      420

cuaacuuccu gaucuggccc ccuugugugg aggucaagcg cugcacuggc uguugcaaua      480

ccucaagcgu gaaaugucag ccaagucgag uacaucacag auccguuaag guggcaaagg      540

ucgaguacgu gaggaaaaag cccaaacuga aggaagugca gguccggcuc gaggaacacu      600

uagagugcgc cugugcuaca accucucuga acccugauua ucgugaagag gacacugggc      660

gcccaagaga gagcggcaaa aagaggaagc ggaaacgacu uaagccgaca ugaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  4165
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt3)

<400>  4165
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagaugcu gggcccuguu ccucagccuu uguugcuacc      120

ugagguuggu guccgcugag ggcgacccca ucccugaaga guuauaugaa augcugucug      180

aucacucaau ucggaguuuu gacgaucuac agcgccuccu gcauggggac ccaggagagg      240

aagauggugc agagcuugac cugaauauga cccgaagcca cuccggcggg gaguuggaau      300

cucucgcccg uggaagaagg ucgcugggcu cacugacaau agcggagccg gcuaugaucg      360

ccgaauguaa gacucggacg gaggucuucg agauuagccg cagacucauc gauaggacca      420

acgcaaacuu uuuaguuugg cccccuugcg uggaaguaca acgguguagu gguugcugua      480

auaaucgcaa cgugcagugc cgaccaacac agguccagcu gagacccgug caaguuagga      540

aaauugagau cgugcggaag aaaccuauau ucaagaaagc cacugucacc cuugaagacc      600

auuuggcuug uaagugcgag acaguggcag ccgcucgucc aguaacccgc ucccccgggg      660

gaucucagga acagagagcc aagacuccuc agacaagggu uaccauccgg acggugcgag      720

uccgcagacc accgaaaggc aagcacagga aauuuaagca uacucacgau aaaaccgcgc      780

ugaaggagac acuaggcgca ugaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  4166
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt3)

<400>  4166
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguucg gccuccuucu guugaccucc gccuuagcug      120

ggcagagaca aggaacacag gcagagucua accugucaag uaaguuucag uucagcucca      180

auaaagaaca gaacggugug caagaccccc agcacgagag gaucauuacu gucucuacga      240

auggcucgau acauucaccu cgguuuccac acaccuaccc gcgcaacaca guucuagugu      300

ggcgacucgu agccguggaa gagaaugucu ggauccagcu gacuuucgau gaacguuuug      360

ggcuugagga ccccgaggau gacauuugca aguaugauuu cguggaaguu gaggaaccua      420

gcgacggaac cauccugggc agauggugug guagugggac agugccagga aaacagauuu      480

ccaagggcaa ccaaaucagg auacgguuug ucucugauga guacuucccc agcgagccug      540

gcuuuugcau ccauuauaau auugugaugc cacaguucac cgaagcggua ucccccucag      600

uuuugccucc aagugcucuc ccgcuggacc ugcucaacaa ugccaucacu gcauuuagca      660

cauuagagga ucugauucgc uaccuugaac ccgagagaug gcaguuggac cuggaagauc      720

uauauaggcc uaccuggcag cuccugggga aagccuucgu guuuggacgg aagucucgcg      780

ucguggaccu uaaccuguug acggaggagg ugcgacucua cuccuguacu ccaagaaauu      840

ucucagucag caucagggag gaacugaagc ggaccgauac aauauucugg cccgguugcu      900

uacugguuaa acguuguggc gggaacugcg cuuguugccu ccacaauugu aacgaaugcc      960

aaugugugcc uaguaaggua acuaaaaagu aucaugaggu gcuucagcug cgcccaaaaa     1020

ccggagucag aggcuugcac aagucucuaa cagacguggc acuggaacac caugaggagu     1080

gcgacugcgu uuguaggggu uccaccgggg gaugaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  4167
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt3)

<400>  4167
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagacuga ucuucgugua cacccucauu ugcgccaacu      120

uuuguagcug cagggacaca uccgcuacuc cccagucugc aucaauaaag gcccuucgga      180

augcgaaccu gcgccgagau gacuuguauc guagagauga gacgauccaa gucaaaggaa      240

auggguacgu ucagaguccu agguucccaa acagcuaucc gcggaauuua cugcuaaccu      300

ggcgccucca uucccaggaa aacacaagga uucagcuggu guuugacaau caauucggac      360

uugaggaagc ugagaacgau aucuguagau acgacuuugu agaaguggag gauauuucug      420

agacuucgac caucauacgg ggucgcuggu gcggccacaa ggaagugccc ccucgaauca      480

aaucaagaac aaaucagauu aagaucaccu ucaaaagcga cgauuauuuu gucgccaagc      540

caggguucaa gauuuacuau agucuguugg aggacuuuca gcccgcagcc gcuuccgaaa      600

cuaacuggga gucuguuaca agcuccaucu caggagugag uuacaauagc ccuucuguca      660

ccgauccaac gcucauagca gacgcccugg auaaaaagau ugcugaguuc gacacugugg      720

aagaccugcu caaauacuuu aaccccgagu ccuggcagga agauuuagag aauauguauc      780

uggacacccc uagguaccgg ggccguucau aucaugaucg caagagcaaa guagaccuug      840

auagauugaa cgacgaugcc aagagguaca guuguacacc acggaauuau ucuguuaaca      900

uccgagagga acugaagcua gcgaacgugg ucuucuuucc gcgcugccuc cuggugcaaa      960

gauguggugg gaauugcgga uguggcacug ugaacuggag guccugcacc uguaauagcg     1020

gcaaaacagu caagaaauac cacgagguuc uucaguucga acccgggcau auuaagcggc     1080

gcggcagagc aaaaaccaug gcccuggugg acauccaguu ggaucaccac gagaggugcg     1140

acugcaucug uucgucucgu ccuccacggu gaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  4168
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt3)

<400>  4168
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugacccaca gcaaguuccc cgccgcuggc auguccagac      120

cucuggacac aucucucagg cuuaaaacuu uuucaaguaa gagcgaguac cagcuggucg      180

uuaacgcagu gcggaaauug caagaauccg gguucuauug gucugccgua acgggaggug      240

aggcgaauuu acugcuaucg gcugaaccag ccggcaccuu ucucauccgc gauucaagcg      300

accagcgaca uuucuuuaca cugaguguga agacucaguc cgggaccaaa aaccuucgua      360

uucagugcga gggaggcucu uucagccugc aauccgaucc gagaucaaca cagcccgucc      420

cuagguuuga cuguguguug aagcucguuc accauuacau gccacccccu ggugcaccaa      480

guuuccccag cccuccaacc gaaccgucuu ccgaggugcc cgagcagccu ucagcccagc      540

cacugcccgg gagcccucca cggcgcgcuu auuacauaua uaguggaggc gaaaagaucc      600

cccugguccu cucuagaccg uuauccagca auguggcaac ucugcaacac cuuugcagga      660

aaacaguaaa cggccauuug gauucguacg agaagguuac ccagcugccu gggcccauuc      720

gggaauuucu agaccaguau gaugccccac ucugaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  4169
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt3)

<400>  4169
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugcccagcg ccggccagcu ggcucucuuc gcacuuggga      120

ucguccuggc cgcgugccag gcuuuggaga acuccaccuc uccuuuauca gccgacccac      180

cgguugcagc cgcuguggua agucacuuua augauugucc cgacagccau acacaauucu      240

gcuuucacgg aacuuguaga uuccuggugc aggaagauaa gccugcaugc gucugucauu      300

ccgguuacgu gggcgccagg ugcgagcacg cugaccuacu cgccguugug gcggcaucuc      360

agaaaaagca agccauuacg gcucuggucg ugguaucgau aguugcccuu gcagugcuga      420

ucauuaccug ugucuugauc cauugcuguc aggugcggaa acacugcgaa uggugucgcg      480

cucucauuug ccgacacgag aagccaucag cccugcugaa agggcguaca gcgugcuguc      540

auagcgaaac uguggucuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  4170
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt3)

<400>  4170
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccccuagcg gccugagacu ccuuccacug uuguuaccgc      120

ugcuauggcu ccuggugcuu acccccggga ggccugccgc uggacugucc acaugcaaga      180

cuaucgacau ggaguugguc aaacggaagc gcauugaagc aauacgaggu cagauccucu      240

cuaaacugcg ucuggccuca ccacccaguc aaggcgaggu uccuccaggg ccccucccug      300

aagcgguguu agcucuguac aacagcacga gagauagggu agccggagag uccgcagaac      360

cagagccgga gcccgaagcc gacuauuacg cuaaggaggu gacccggguc cuuauggugg      420

aaacacacaa ugagauuuau gauaaauuca agcagucuac ucauucgauc uacauguuuu      480

ucaacaccuc agaguugcgc gaagcaguuc cugagccagu gcugcuaagc agagccgaac      540

ucaggcugcu ucggcugaag uugaaagucg agcagcacgu ggaacucuau cagaaguaca      600

guaauaacuc cuggcgcuau cugucuaauc gauuacuggc ucccagcgac uccccugagu      660

ggcucucauu ugauguaaca ggcguuguga gacaauggcu uaguaggggu ggggagauug      720

aaggauuccg gcugagcgcc cauuguucuu gcgacucccg ugauaacacc uugcaggucg      780

acaucaaugg cuuuacuaca ggccgcagag gggaucuagc gaccauacac ggaaugaaca      840

ggccauuccu gcuccugaug gcaacgcccc uugagcgggc ccagcaucug cagucaagcc      900

gacaccgcag agcuuuggac acuaauuacu guuuuaguuc uaccgagaaa aacugcugug      960

ugaggcaacu cuacaucgau uuccggaagg accuggguug gaaauggauu cacgaaccga     1020

agggcuauca ugccaauuuu ugcuuagggc cuugucccua caucuggucc cuggauacac     1080

aguauagcaa ggugcuagca cucuacaacc agcacaaucc aggagcuucg gccgcgccuu     1140

gcuguguccc ccaggcccug gaaccacuuc ccauuguuua uuacgugggc cgcaaaccua     1200

agguagagca auugucuaac augaucguga gauccugcaa auguucauga ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  4171
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt3)

<400>  4171
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg ugcugagcgc cuuccucauc cuucaucugg      120

ucaccguugc uuuguccuua ucuacauguu caacucugga cauggaucag uuuaugagaa      180

agaggauuga ggcaauacgg ggccaaaucc uaaguaaacu caagcugacg agcccucccg      240

aagacuaucc agagccggaa gaggugcccc cugaaguaau uuccaucuac aacucuaccc      300

gcgaucuucu gcaggagaaa gccucgcgac gugcggcugc cugcgagaga gaaaggucag      360

acgaggaaua uuacgcaaag gagguguaua aaauugauau gccacccuuc uuuccuagcg      420

agaaugccau cccacccaca uucuaccggc cuuauuuucg cauagucaga uucgacguga      480

gugcuaugga aaagaacgca uccaauuugg uuaaggccga guuuagggug uuccggcucc      540

agaacccaaa agcucgcguc ccggaacagc gaaucgagcu guaccaaauu cugaagucua      600

aagaucucac uagccccacc cagagauaca ucgacuccaa ggugguaaaa acaagggccg      660

aaggggagug guuaucauuu gauguuaccg acgcggugca cgaguggcug caucacaagg      720

aucggaaucu uggauucaag auuaguuugc auuguccuug cuguacuuuu gucccaagca      780

acaauuauau cauacccaac aaaucugagg aacuggaagc acguuucgcc gguauugacg      840

gcacauccac cuacacguca ggggaucaga agacuaucaa aagcacccgc aagaaaaaua      900

guggaaagac accucaccua cuccugaugc uucugccauc uuauagauug gagucccagc      960

aaacuaacag gcggaaaaag cgagcucucg acgccgcaua cugcuuucgc aaugugcagg     1020

acaacuguug ccugagaccc uuauauauug auuucaagag ggaccugggc uggaaaugga     1080

uccacgaacc gaaggguuac aaugcuaacu ucugugccgg ggcgugcccu uaucucugga     1140

gcucggauac ccagcauucu cgggugcuuu cccuguacaa uacaaucaac cccgaggccu     1200

cagcaagucc auguugcguc agccaggacu uggagccucu aaccauucug uacuauauag     1260

gaaaaacgcc caagaucgaa caacucucca acaugauugu uaaaucuugc aaguguagcu     1320

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  4172
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt3)

<400>  4172
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcauc ugcagagagc ccucgugguc cuugcucugu      120

ugaacuucgc aaccguuagc uuaucccugu cuacaugcac uacgcuagac uuuggccaca      180

ucaaaaagaa aaggguggag gccauucggg ggcaaauacu cucaaagcug cgccuuacca      240

gucccccuga accaacagua augacucacg ugccguacca gguccuggcg uuguauaaua      300

gcacccgaga gcuccuggaa gagaugcaug gagaacguga ggaggguugu acacaggaaa      360

acaccgaguc cgaauacuau gcuaaagaga uccacaaguu cgauaugauu cagggccugg      420

ccgagcauaa ugaacucgca gugugcccca aggggaucac uucuaaaguu uuuagauuca      480

acgugucguc agucgagaag aauaggacaa acuuauuucg ggccgaguuc cgcgugcuga      540

gaguaccuaa uccaagcagu aaaaggaacg aacaacggau ugaacuuuuu cagaucuugc      600

gccccgacga gcacauagcu aagcagcgau acaucggagg caaaaaucug ccuaccagag      660

guacggcaga guggcuaucc uucgauguua cugacaccgu gagggaaugg cuccugcggc      720

gugagucuaa ccuugggcug gaaauuagca uccacugucc augccauaca uuucagccca      780

auggagauau uuuggagaac auccacgaag ucauggagau aaaguucaag ggcguggaca      840

augaggauga ccauggccgc ggggaucucg gaagacugaa aaagcaaaaa gaccaccaca      900

acccucauuu aauucugaug augaucccac cgcacaggcu cgauaauccc ggucagggcg      960

ggcagcggaa gaaacgagcc cuugacacua acuauuguuu ucgcaaccug gaagagaauu     1020

gcugugugag accuuuguac auugauuuca ggcaggaccu aggauggaag uggguccaug     1080

aaccaaaagg cuauuacgcu aacuuuugcu ccggucccug uccuuaccug cggucagccg     1140

acaccacaca caguaccguu cucgggcugu auaauacgcu uaacccagag gcgagcgcau     1200

cucccugcug ugugccgcaa gaucuggaac cuuugacuau ccucuacuau guaggacgca     1260

cacccaaggu ggagcagcug uccaauaugg ucgugaaguc augcaaaugc agcugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4173
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt3)

<400>  4173
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccccgugg cugucugggc agcccuggcg guuggccucg      120

agcuuugggc ugccgcacac gcccugccug cucagguggc auucacccca uacgccccgg      180

aacccgggag cacaugcaga uugagggagu auuacgacca aacugcucag auguguugcu      240

ccaaguguuc uccuggacag caugccaaag uauuuugcac gaagaccuca gauacagugu      300

gugacaguug cgaagauagc acuuauaccc aguuauggaa cuggguccca gagugucugu      360

ccugcgguuc ucgguguucg ucagaccaag uggaaacaca ggcgugcacc cgcgagcaga      420

aucgaaucug uacuugccgu cccggcuggu acugcgcacu aagcaaacag gaggggugua      480

gacucugcgc cccucugagg aagugucggc caggauucgg cguugcucgc cccgguacag      540

aaaccaguga uguggucugc aaaccuugug ccccagggac guuuuccaac acuaccucua      600

gcacagacau uugcagaccg caccaaauau guaauguggu agcaaucccc ggaaacgcuu      660

ccauggaugc cguuugcacu ucaaccaguc cuacaaggag cauggcgcca ggcgccgugc      720

aucuucccca gccugucucu acccgguccc agcacacgca gccaacuccc gagccgucaa      780

cagcaccuag caccaguuuc cuguugccca ugggcccauc uccucccgcu gaagggucca      840

cuggagacuu ugcccuccca gugggucuga uugugggcgu cacagcucug gggcucuuaa      900

ucauuggagu ugugaauugu guaaucauga cccaagugaa gaagaaaccc cugugccuuc      960

agcgcgaggc caaggucccu cauuugccag cagauaaagc ccgaggcacg caggguccgg     1020

agcaacagca ucugcuaaua accgcuccca gcucgucuuc cucaagucuc gaaagcuccg     1080

cgucugcacu ggacagaagg gccccuacac ggaaccagcc acaggcuccc gggguggagg     1140

ccagcggagc aggcgaagcc cgugcuucaa cuggcaguuc cgauagcucu ccugggggac     1200

acgguaccca aguuaaugug acauguaucg ucaacgugug cucaaguagc gaccacuccu     1260

cucagugcuc gagccaggcc uccucaacua ugggcgauac cgacaguucu ccaagcgagu     1320

cccccaagga cgaacaggua ccguucucaa aagaggagug ugcauuucgc agccaacuug     1380

aaacaccuga gacccuguug gggucuacug aagagaagcc acucccccug ggaguuccug     1440

augcgggcau gaagcccucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  4174
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt3)

<400>  4174
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgugauga gacuguuccc uugcuuucuc cagcuucugg      120

ccggcuuggc uuuaccagca gucccgcccc aacagugggc ccugagcgcg gggaacggau      180

ccucugaggu ugaaguggua ccuuuccagg aggugugggg uaggucauac ugucgggcuc      240

uagaacgccu cgucgacgug guuagugagu auccaagcga aguggagcac auguuuuccc      300

ccucuugcgu cucgcugcuu cgauguaccg gcugcugugg ggaugagaau cugcauugcg      360

ugccuguaga aacagccaac guuacuaugc aguugcucaa gauccguuca ggagacagac      420

caagcuacgu ggagcugacg uucagucaac acgucaggug ugaaugccgg ccccugcgcg      480

agaaaaugaa gccugagaga aggcggccaa aaggccgcgg uaagcgaaga agggaaaaac      540

agcggccgac cgauugucau cucugcgggg acgcagugcc ccgucgcuga ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  4175
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt3)

<400>  4175
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgacagac agacagauac ugcccccagc ccuuccuacc      120

aucugcuccc aggcaggcgg cgcacggugg acgcugcagc cucucgaggg caaggaccgg      180

agcccgcgcc ugguggcggg gucgaaggag uuggcgcucg ugguguggcc cuuaagcugu      240

ucguacaguu guuagggugc ucaagauuug gaggcgcagu ggucagggcc ggcgaggcug      300

aaccaagugg ggcagcccgg agcgcuuccu cuggacgcga ggaaccccag ccugaggagg      360

gugaagagga agaggagaaa gaagaggaaa gaggcccaca guggaggcug ggggcccgga      420

agcccggauc guggaccggc gaggcggcag ugugugccga uucagcuccu gccgcacgcg      480

cuccacaagc ccuagcgcga gccagcggua gagggggaag gguugcacgg cguggcgcug      540

aagagagugg cccgccccac uccccuucuc gcagagggag cgccuccagg gcuggaccag      600

gucgggccuc agagacaaug aacuuccucc ugaguugggu gcacuggagc cuugcacugu      660

ugcucuaucu gcaucacgcc aaauggucuc aggcugcgcc cauggcagaa ggcgggggac      720

agaaucauca cgaggucgug aaguuuaugg acguauacca gcgauccuau ugccacccua      780

ucgaaacucu gguugauauu uuccaagagu acccagacga aauagaguau aucuuuaaac      840

ccucaugugu gccgcucaug cgcugcggcg guuguugcaa cgaugagggg uuagaaugug      900

ucccuaccga ggaaagcaau auuacaaugc agaucaugag aauuaagccc caucagggcc      960

agcacaucgg agagaugagu uuccugcaac auaacaagug cgaauguagg ccuaaaaagg     1020

accgggcccg ccaggagaaa aagucuguga gaggcaaagg gaagggacag aagaggaaac     1080

guaagaaauc ccgguacaag agcuggucgg uguaugucgg ugcucgaugc ugucuuaugc     1140

cauggucuuu gcccggccca caccccugcg ggccuugcuc cgagagaagg aaacaccugu     1200

uuguucaaga uccacagacc uguaagugcu cauguaaaaa uacugacagu cgcugcaagg     1260

cccggcagcu agaacucaac gagagaacau guaggugcga uaagccgcgc cgaugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4176
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt3)

<400>  4176
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggucc cuugcccugu      120

uguuauaccu gcaucacgcu aaguggucuc aggcagcccc cauggcggag ggcgggggac      180

aaaaucauca cgaagucguu aaauuuaugg acguguauca gagaucauac ugccauccua      240

ucgagacccu aguagauauu uuccaggaau auccagacga gauagaauac aucuuuaagc      300

cgaguugugu gccccucaug aggugcggug gcuguugcaa cgaugagggg cuggagugug      360

ucccuacaga agagagcaau auuacuaugc agaucaugcg gauuaaacca caccaaggac      420

agcacaucgg cgaaaugucc uuccuucagc auaacaagug cgagugucgc cccaaaaagg      480

accgagcucg ucaggagaag aaaucuguga gagguaaggg gaaaggacaa aagaggaaac      540

ggaagaaguc gcgcuauaaa ucauggagcg uuuacguggg cgccagaugc ugucugaugc      600

cuuggaguuu gccaggcccc cacccuugcg ggccauguuc cgaaaggcgg aagcaucucu      660

uuguccagga uccgcagacg ugcaaaugcu cuuguaagaa uaccgacagc cgcugcaaag      720

cacgacagcu ggagcugaac gaaagaacau guaggugcga uaagccccgg cguugaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  4177
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt3)

<400>  4177
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcccccugc ucagaaggcu ucuguuggcc gcuuuacugc      120

agcuagcccc ugcacaagcg ccaguguccc agccggacgc ucccggccac cagcggaagg      180

ucguuucuug gaucgaugug uacacccgcg ccacaugcca gccucgagag guaguggucc      240

cacucacugu ggaacugaug gggacgguug caaaacaacu ugugcccuca ugugucaccg      300

ugcagcguug cggagguugu ugcccugacg auggccugga guguguacca acagggcagc      360

aucagguuag aaugcaaauu uugaugauaa gguaucccag uagccagcuc ggagaaaugu      420

cccuggagga acacucucag ugcgaguguc ggccuaagaa aaaggacucg gccgugaaac      480

cagaucgcgc ugcaacuccg caucacagac cccagccuag gucaguccca ggcugggaca      540

gcgcccccgg ugcuccuagu ccagccgaua ucacccaucc cacaccggcg ccugggcccu      600

ccgcacacgc cgcuccaucu accacuagcg cccugacacc uggacccgca gcugccgcgg      660

ccgacgcagc ugccuccuca guggcuaagg gcggcgccug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  4178
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt3)

<400>  4178
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuucucg gcuucuuuag cguggccugc ucccuucugg      120

cugcagccuu guuacccggg ccuagagagg cgccagcugc cgcagccgcu uucgaaucug      180

gacuggaccu aucagaugca gagccggacg ccggugaagc uaccgccuac gcgaguaagg      240

aucucgagga acagcugagg agcgucuccu cuguugacga gcuuaugaca gugcuguauc      300

ccgaguacug gaaaauguau aagugucaau ugcggaaagg cggguggcag cauaaccgcg      360

aacaggcaaa ucucaacucg cgaacugagg aaacgaucaa guuugccgcu gcccacuaca      420

auaccgagau ucugaaauca auagauaacg aguggcguaa gacacagugc augccuagag      480

aaguauguau cgacguggga aaggaguucg gcgucgcaac uaauaccuuu uucaaaccac      540

ccugcgugag cguuuauagg uguggugggu gcuguaacag ugaaggacug caaugcauga      600

auacauccac cucuuaccuc agcaagacuu uauuugagau uacagugccu cugucccagg      660

gcccaaaacc cgucaccauc ucauucgcua accauacgag uugucggugc augagcaagc      720

uggaugugua ucgccaggua cacucuauua ucagaagguc cuugccugcc acucugccac      780

agugucaagc ggccaauaaa accugcccga caaacuacau guggaauaac cauauaugcc      840

ggugucuagc acaggaagac uuuauguucu caagcgaugc uggcgacgau aguacugacg      900

gguuucacga uaucugcgga cccaauaagg agcucgacga ggaaaccugu cagugcguuu      960

gucgcgccgg ucugcgaccu gcuucuugcg gcccacacaa ggagcuugac agaaacuccu     1020

gucagugcgu guguaaaaau aagcuguucc ccagccaaug cggggccaac agggaauuug     1080

augagaacac augucagugc gucugcaaac ggaccugucc ucguaaucag ccauugaacc     1140

ccggaaagug cgcaugugaa ugcacggagu cgccgcaaaa augucuccug aagggcaaaa     1200

aguuccauca ccagacuugc ucuuguuacc gcagaccuug cacaaauagg cagaaggccu     1260

gugagcccgg uuucuccuau ucagaagagg ugugccggug ugugccaagu uacuggaaac     1320

gaccucagau gagcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  4179
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt3)

<400>  4179
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagagu ggguggucgu uaacguguuc augaugcugu      120

auguacagcu cgugcaaggc agcuccaaug aacacgggcc cgucaagagg ucuucacaga      180

guacccuuga gcggagcgaa cagcagaucc gcgccgcuuc cucucuggag gaauuguuac      240

gaauuacaca uucggaggac uggaaacugu ggcguugcag acuaaggcuc aagucauuua      300

cuagcaugga uagucggucc gcaucucacc gcagcacgag auucgccgcg accuuuuacg      360

acauagagac acugaaagug aucgaugaag aguggcaaag gacucagugu uccccucggg      420

aaaccugcgu ugagguggcu ucagagcuug gaaagaguac aaacaccuuc uuuaaaccac      480

cgugugucaa uguguuccgc ugcgguggcu guugcaacga agagagccug auuuguauga      540

auacuucuac auccuauauc ucaaagcagu uguuugaaau uagcguaccc cucaccagug      600

uuccugagcu ggugccaguc aagguggcca accauacggg gugcaaaugu cugcccacug      660

caccucgaca cccauacucu aucauaagaa gguccaucca gauucccgaa gaggaccggu      720

gcagccauuc gaagaaacuc uguccuaucg auauguuaug ggacucuaau aagugcaaau      780

gcgugcugca agaggaaaac ccacuugccg gaaccgagga ucacucccac uugcaggaac      840

cggcucugug uggcccccau augauguucg acgaggaucg uugcgaaugu gucugcaaga      900

caccuugucc aaaggaccua auucagcacc ccaaaaauug cucauguuuu gagugcaagg      960

agagucucga aacuuguugc cagaaacaua agcuguucca cccugauacc uguagcugcg     1020

aggaccgcug cccauuucac acaagacccu gugcauccgg uaaaaccgcc ugcgcuaagc     1080

auuguagguu cccgaaagaa aagcgggccg cgcaagggcc ucacucucga aagaaccccu     1140

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  4180
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt4)

<400>  4180
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgacg agaccggcuu cgagcacagc ggccuguggg      120

ugagcgugcu ggccggccug cugcugggcg ccugccaggc ccaccccauc cccgacagca      180

gcccccugcu gcaguucggc ggccagguga gacagagaua ccuguacacc gacgacgccc      240

agcagaccga ggcccaccug gagaucagag aggacggcac cgugggcggc gccgccgacc      300

agagccccga gagccugcug cagcugaagg cccugaagcc cggcgugauc cagauccugg      360

gcgugaagac cagcagauuc cugugccaga gacccgacgg cgcccuguac ggcagccugc      420

acuucgaccc cgaggccugc agcuucagag agcugcugcu ggaggacggc uacaacgugu      480

accagagcga ggcccacggc cugccccugc accugcccgg caacaagagc ccccacagag      540

accccgcccc cagaggcccc gccagauucc ugccccugcc cggccugccc cccgcccugc      600

ccgagccccc cggcauccug gccccccagc cccccgacgu gggcagcagc gacccccuga      660

gcaugguggg ccccagccag ggcagaagcc ccagcuacgc cagcugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  4181
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt4)

<400>  4181
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuucc ccccccugcu gcugcugcug uucuggggcg      120

uggugagcca cagcuucccc gccacccugg agacccagga gcaggacgug gaccuggugc      180

agaaguaccu ggagaaguac uacaaccuga agaacgacgg cagacaggug gagaagagaa      240

gaaacagcgg ccccguggug gagaagcuga agcagaugca ggaguucuuc ggccugaagg      300

ugaccggcaa gcccgacgcc gagacccuga aggugaugaa gcagcccaga ugcggcgugc      360

ccgacguggc ccaguucgug cugaccgagg gcaaccccag augggagcag acccaccuga      420

ccuacagaau cgagaacuac acccccgacc ugcccagagc cgacguggac cacgccaucg      480

agaaggccuu ccagcugugg agcaacguga ccccccugac cuucaccaag gugagcgagg      540

gccaggccga caucaugauc agcuucguga gaggcgacca cagagacaac agccccuucg      600

acggccccgg cggcaaccug gcccacgccu uccagcccgg ccccggcauc ggcggcgacg      660

cccacuucga cgaggacgag agauggacca acaacuucag agaguacaac cugcacagag      720

uggccgccca cgagcugggc cacagccugg gccugagcca cagcaccgac aucggcgccc      780

ugauguaccc cagcuacacc uucagcggcg acgugcagcu ggcccaggac gacaucgacg      840

gcauccaggc caucuacggc agaagccaga accccgugca gcccaucggc ccccagaccc      900

ccaaggccug cgacagcaag cugaccuucg acgccaucac caccaucaga ggcgagguga      960

uguucuucaa ggacagauuc uacaugagaa ccaaccccuu cuaccccgag guggagcuga     1020

acuucaucag cguguucugg ccccagcugc ccaacggccu ggaggccgcc uacgaguucg     1080

ccgacagaga cgaggugaga uucuucaagg gcaacaagua cugggccgug cagggccaga     1140

acgugcugca cggcuacccc aaggacaucu acagcagcuu cggcuucccc agaaccguga     1200

agcacaucga cgccgcccug agcgaggaga acaccggcaa gaccuacuuc uucguggcca     1260

acaaguacug gagauacgac gaguacaaga gaagcaugga ccccggcuac cccaagauga     1320

ucgcccacga cuuccccggc aucggccaca agguggacgc cguguucaug aaggacggcu     1380

ucuucuacuu cuuccacggc accagacagu acaaguucga ccccaagacc aagagaaucc     1440

ugacccugca gaaggccaac agcugguuca acugcagaaa gaacugagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  4182
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt4)

<400>  4182
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuucc ccccccugcu gcugcugcug uucuggggcg      120

uggugagcca cagcuucgug cugaccgagg gcaaccccag augggagcag acccaccuga      180

ccuacagaau cgagaacuac acccccgacc ugcccagagc cgacguggac cacgccaucg      240

agaaggccuu ccagcugugg agcaacguga ccccccugac cuucaccaag gugagcgagg      300

gccaggccga caucaugauc agcuucguga gaggcgacca cagagacaac agccccuucg      360

acggccccgg cggcaaccug gcccacgccu uccagcccgg ccccggcauc ggcggcgacg      420

cccacuucga cgaggacgag agauggacca acaacuucag agaguacaac cugcacagag      480

uggccgccca cgagcugggc cacagccugg gccugagcca cagcaccgac aucggcgccc      540

ugauguaccc cagcuacacc uucagcggcg acgugcagcu ggcccaggac gacaucgacg      600

gcauccaggc caucuacggc agaagccaga accccgugca gcccaucggc ccccagaccc      660

ccaaggccug cgacagcaag cugaccuucg acgccaucac caccaucaga ggcgagguga      720

uguucuucaa ggacagauuc uacaugagaa ccaaccccuu cuaccccgag guggagcuga      780

acuucaucag cguguucugg ccccagcugc ccaacggccu ggaggccgcc uacgaguucg      840

ccgacagaga cgaggugaga uucuucaagg gcaacaagua cugggccgug cagggccaga      900

acgugcugca cggcuacccc aaggacaucu acagcagcuu cggcuucccc agaaccguga      960

agcacaucga cgccgcccug agcgaggaga acaccggcaa gaccuacuuc uucguggcca     1020

acaaguacug gagauacgac gaguacaaga gaagcaugga ccccggcuac cccaagauga     1080

ucgcccacga cuuccccggc aucggccaca agguggacgc cguguucaug aaggacggcu     1140

ucuucuacuu cuuccacggc accagacagu acaaguucga ccccaagacc aagagaaucc     1200

ugacccugca gaaggccaac agcugguuca acugcagaaa gaacugagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  4183
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt4)

<400>  4183
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaagaaca uccugaagau ccugauggac agcuacagca      120

aggagagcaa gauccagacc gugagaagag ugaccagcgu gagccugcug gccguguacc      180

ugaccaugaa caccagcagc cuggugcugg ccaagcccau cgagaacacc aacgacacca      240

gcaucaagaa cguggagaag cugagaaacg cccccaacga ggagaacagc aagaaggugg      300

aggacagcaa gaacgacaag guggagcacg ugaagaacau cgaggaggcc aagguggagc      360

agguggcccc cgaggugaag agcaagagca cccugagaag cgccagcauc gccaacacca      420

acagcgagaa guacgacuuc gaguaccuga acggccugag cuacaccgag cugaccaacc      480

ugaucaagaa caucaagugg aaccagauca acggccuguu caacuacagc accggcagcc      540

agaaguucuu cggcgacaag aacagagugc aggccaucau caacgcccug caggagagcg      600

gcagaaccua caccgccaac gacaugaagg gcaucgagac cuucaccgag gugcugagag      660

ccggcuucua ccugggcuac uacaacgacg gccugagcua ccugaacgac agaaacuucc      720

aggacaagug cauccccgcc augaucgcca uccagaagaa ccccaacuuc aagcugggca      780

ccgccgugca ggacgaggug aucaccagcc ugggcaagcu gaucggcaac gccagcgcca      840

acgccgaggu ggugaacaac ugcgugcccg ugcugaagca guucagagag aaccugaacc      900

aguacgcccc cgacuacgug aagggcaccg ccgugaacga gcugaucaag ggcaucgagu      960

ucgacuucag cggcgccgcc uacgagaagg acgugaagac caugcccugg uacggcaaga     1020

ucgaccccuu caucaacgag cugaaggccc ugggccugua cggcaacauc accagcgcca     1080

ccgagugggc cagcgacgug ggcaucuacu accugagcaa guucggccug uacagcacca     1140

acagaaacga caucgugcag agccuggaga aggccgugga cauguacaag uacggcaaga     1200

ucgccuucgu ggccauggag agaaucaccu gggacuacga cggcaucggc agcaacggca     1260

agaaggugga ccacgacaag uuccuggacg acgccgagaa gcacuaccug cccaagaccu     1320

acaccuucga caacggcacc uucaucauca gagccggcga caaggugagc gaggagaaga     1380

ucaagagacu guacugggcc agcagagagg ugaagagcca guuccacaga guggugggca     1440

acgacaaggc ccuggaggug ggcaacgccg acgacgugcu gaccaugaag aucuucaaca     1500

gccccgagga guacaaguuc aacaccaaca ucaacggcgu gagcaccgac aacggcggcc     1560

uguacaucga gcccagaggc accuucuaca ccuacgagag aaccccccag cagagcaucu     1620

ucagccugga ggagcuguuc agacacgagu acacccacua ccugcaggcc agauaccugg     1680

uggacggccu guggggccag ggccccuucu acgagaagaa cagacugacc ugguucgacg     1740

agggcaccgc cgaguucuuc gccggcagca ccagaaccag cggcgugcug cccagaaaga     1800

gcauccuggg cuaccuggcc aaggacaagg uggaccacag auacagccug aagaagaccc     1860

ugaacagcgg cuacgacgac agcgacugga uguucuacaa cuacggcuuc gccguggccc     1920

acuaccugua cgagaaggac augcccaccu ucaucaagau gaacaaggcc auccugaaca     1980

ccgacgugaa gagcuacgac gagaucauca agaagcugag cgacgacgcc aacaagaaca     2040

ccgaguacca gaaccacauc caggagcugg ccgacaagua ccagggcgcc ggcauccccc     2100

uggugagcga cgacuaccug aaggaccacg gcuacaagaa ggccagcgag guguacagcg     2160

agaucagcaa ggccgccagc cugaccaaca ccagcgugac cgccgagaag agccaguacu     2220

ucaacaccuu cacccugaga ggcaccuaca ccggcgagac cagcaagggc gaguucaagg     2280

acugggacga gaugagcaag aagcuggacg gcacccugga gagccuggcc aagaacagcu     2340

ggagcggcua caagacccug accgccuacu ucaccaacua cagagugacc agcgacaaca     2400

aggugcagua cgacguggug uuccacggcg ugcugaccga caacgccgac aucagcaaca     2460

acaaggcccc caucgccaag gugaccggcc ccagcaccgg cgccgugggc agaaacaucg     2520

aguucagcgg caaggacagc aaggacgagg acggcaagau cgugagcuac gacugggacu     2580

ucggcgacgg cgccaccagc agaggcaaga acagcgugca cgccuacaag aaggccggca     2640

ccuacaacgu gacccugaag gugaccgacg acaagggcgc caccgccacc gagagcuuca     2700

ccaucgagau caagaacgag gacaccacca cccccaucac caaggagaug gagcccaacg     2760

acgacaucaa ggaggccaac ggccccaucg uggagggcgu gaccgugaag ggcgaccuga     2820

acggcagcga cgacgccgac accuucuacu ucgacgugaa ggaggacggc gacgugacca     2880

ucgagcugcc cuacagcggc agcagcaacu ucaccuggcu gguguacaag gagggcgacg     2940

accagaacca caucgccagc ggcaucgaca agaacaacag caaggugggc accuucaaga     3000

gcaccaaggg cagacacuac guguucaucu acaagcacga cagcgccagc aacaucagcu     3060

acagccugaa caucaagggc cugggcaacg agaagcugaa ggagaaggag aacaacgaca     3120

gcagcgacaa ggccaccgug auccccaacu ucaacaccac caugcagggc agccugcugg     3180

gcgacgacag cagagacuac uacagcuucg aggugaagga ggagggcgag gugaacaucg     3240

agcuggacaa gaaggacgag uucggcguga ccuggacccu gcaccccgag agcaacauca     3300

acgacagaau caccuacggc cagguggacg gcaacaaggu gagcaacaag gugaagcuga     3360

gacccggcaa guacuaccug cugguguaca aguacagcgg cagcggcaac uacgagcuga     3420

gagugaacaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  4184
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt4)

<400>  4184
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcuguuc cuguucagca      120

gcgccuacag caucgccaac accaacagcg agaaguacga cuucgaguac cugaacggcc      180

ugagcuacac cgagcugacc aaccugauca agaacaucaa guggaaccag aucaacggcc      240

uguucaacua cagcaccggc agccagaagu ucuucggcga caagaacaga gugcaggcca      300

ucaucaacgc ccugcaggag agcggcagaa ccuacaccgc caacgacaug aagggcaucg      360

agaccuucac cgaggugcug agagccggcu ucuaccuggg cuacuacaac gacggccuga      420

gcuaccugaa cgacagaaac uuccaggaca agugcauccc cgccaugauc gccauccaga      480

agaaccccaa cuucaagcug ggcaccgccg ugcaggacga ggugaucacc agccugggca      540

agcugaucgg caacgccagc gccaacgccg agguggugaa caacugcgug cccgugcuga      600

agcaguucag agagaaccug aaccaguacg cccccgacua cgugaagggc accgccguga      660

acgagcugau caagggcauc gaguucgacu ucagcggcgc cgccuacgag aaggacguga      720

agaccaugcc cugguacggc aagaucgacc ccuucaucaa cgagcugaag gcccugggcc      780

uguacggcaa caucaccagc gccaccgagu gggccagcga cgugggcauc uacuaccuga      840

gcaaguucgg ccuguacagc accaacagaa acgacaucgu gcagagccug gagaaggccg      900

uggacaugua caaguacggc aagaucgccu ucguggccau ggagagaauc accugggacu      960

acgacggcau cggcagcaac ggcaagaagg uggaccacga caaguuccug gacgacgccg     1020

agaagcacua ccugcccaag accuacaccu ucgacaacgg caccuucauc aucagagccg     1080

gcgacaaggu gagcgaggag aagaucaaga gacuguacug ggccagcaga gaggugaaga     1140

gccaguucca cagaguggug ggcaacgaca aggcccugga ggugggcaac gccgacgacg     1200

ugcugaccau gaagaucuuc aacagccccg aggaguacaa guucaacacc aacaucaacg     1260

gcgugagcac cgacaacggc ggccuguaca ucgagcccag aggcaccuuc uacaccuacg     1320

agagaacccc ccagcagagc aucuucagcc uggaggagcu guucagacac gaguacaccc     1380

acuaccugca ggccagauac cugguggacg gccugugggg ccagggcccc uucuacgaga     1440

agaacagacu gaccugguuc gacgagggca ccgccgaguu cuucgccggc agcaccagaa     1500

ccagcggcgu gcugcccaga aagagcaucc ugggcuaccu ggccaaggac aagguggacc     1560

acagauacag ccugaagaag acccugaaca gcggcuacga cgacagcgac uggauguucu     1620

acaacuacgg cuucgccgug gcccacuacc uguacgagaa ggacaugccc accuucauca     1680

agaugaacaa ggccauccug aacaccgacg ugaagagcua cgacgagauc aucaagaagc     1740

ugagcgacga cgccaacaag aacaccgagu accagaacca cauccaggag cuggccgaca     1800

aguaccaggg cgccggcauc ccccugguga gcgacgacua ccugaaggac cacggcuaca     1860

agaaggccag cgagguguac agcgagauca gcaaggccgc cagccugacc aacaccagcg     1920

ugaccgccga gaagagccag uacuucaaca ccuucacccu gagaggcacc uacaccggcg     1980

agaccagcaa gggcgaguuc aaggacuggg acgagaugag caagaagcug gacggcaccc     2040

uggagagccu ggccaagaac agcuggagcg gcuacaagac ccugaccgcc uacuucacca     2100

acuacagagu gaccagcgac aacaaggugc aguacgacgu gguguuccac ggcgugcuga     2160

ccgacaacgc cgacaucagc aacaacaagg cccccaucgc caaggugacc ggccccagca     2220

ccggcgccgu gggcagaaac aucgaguuca gcggcaagga cagcaaggac gaggacggca     2280

agaucgugag cuacgacugg gacuucggcg acggcgccac cagcagaggc aagaacagcg     2340

ugcacgccua caagaaggcc ggcaccuaca acgugacccu gaaggugacc gacgacaagg     2400

gcgccaccgc caccgagagc uucaccaucg agaucaagaa cgaggacacc accaccccca     2460

ucaccaagga gauggagccc aacgacgaca ucaaggaggc caacggcccc aucguggagg     2520

gcgugaccgu gaagggcgac cugaacggca gcgacgacgc cgacaccuuc uacuucgacg     2580

ugaaggagga cggcgacgug accaucgagc ugcccuacag cggcagcagc aacuucaccu     2640

ggcuggugua caaggagggc gacgaccaga accacaucgc cagcggcauc gacaagaaca     2700

acagcaaggu gggcaccuuc aagagcacca agggcagaca cuacguguuc aucuacaagc     2760

acgacagcgc cagcaacauc agcuacagcc ugaacaucaa gggccugggc aacgagaagc     2820

ugaaggagaa ggagaacaac gacagcagcg acaaggccac cgugaucccc aacuucaaca     2880

ccaccaugca gggcagccug cugggcgacg acagcagaga cuacuacagc uucgagguga     2940

aggaggaggg cgaggugaac aucgagcugg acaagaagga cgaguucggc gugaccugga     3000

cccugcaccc cgagagcaac aucaacgaca gaaucaccua cggccaggug gacggcaaca     3060

aggugagcaa caaggugaag cugagacccg gcaaguacua ccugcuggug uacaaguaca     3120

gcggcagcgg caacuacgag cugagaguga acaagugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  4185
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt4)

<400>  4185
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcuguuc cuguucagca      120

gcgccuacag caugaagaag aacauccuga agauccugau ggacagcuac agcaaggaga      180

gcaagaucca gaccgugaga agagugacca gcgugagccu gcuggccgug uaccugacca      240

ugaacaccag cagccuggug cuggccaagc ccaucgagaa caccaacgac accagcauca      300

agaacgugga gaagcugaga aacgccccca acgaggagaa cagcaagaag guggaggaca      360

gcaagaacga caagguggag cacgugaaga acaucgagga ggccaaggug gagcaggugg      420

cccccgaggu gaagagcaag agcacccuga gaagcgccag cagaagaaga agaaagagaa      480

ucgccaacac caacagcgag aaguacgacu ucgaguaccu gaacggccug agcuacaccg      540

agcugaccaa ccugaucaag aacaucaagu ggaaccagau caacggccug uucaacuaca      600

gcaccggcag ccagaaguuc uucggcgaca agaacagagu gcaggccauc aucaacgccc      660

ugcaggagag cggcagaacc uacaccgcca acgacaugaa gggcaucgag accuucaccg      720

aggugcugag agccggcuuc uaccugggcu acuacaacga cggccugagc uaccugaacg      780

acagaaacuu ccaggacaag ugcauccccg ccaugaucgc cauccagaag aaccccaacu      840

ucaagcuggg caccgccgug caggacgagg ugaucaccag ccugggcaag cugaucggca      900

acgccagcgc caacgccgag guggugaaca acugcgugcc cgugcugaag caguucagag      960

agaaccugaa ccaguacgcc cccgacuacg ugaagggcac cgccgugaac gagcugauca     1020

agggcaucga guucgacuuc agcggcgccg ccuacgagaa ggacgugaag accaugcccu     1080

gguacggcaa gaucgacccc uucaucaacg agcugaaggc ccugggccug uacggcaaca     1140

ucaccagcgc caccgagugg gccagcgacg ugggcaucua cuaccugagc aaguucggcc     1200

uguacagcac caacagaaac gacaucgugc agagccugga gaaggccgug gacauguaca     1260

aguacggcaa gaucgccuuc guggccaugg agagaaucac cugggacuac gacggcaucg     1320

gcagcaacgg caagaaggug gaccacgaca aguuccugga cgacgccgag aagcacuacc     1380

ugcccaagac cuacaccuuc gacaacggca ccuucaucau cagagccggc gacaagguga     1440

gcgaggagaa gaucaagaga cuguacuggg ccagcagaga ggugaagagc caguuccaca     1500

gagugguggg caacgacaag gcccuggagg ugggcaacgc cgacgacgug cugaccauga     1560

agaucuucaa cagccccgag gaguacaagu ucaacaccaa caucaacggc gugagcaccg     1620

acaacggcgg ccuguacauc gagcccagag gcaccuucua caccuacgag agaacccccc     1680

agcagagcau cuucagccug gaggagcugu ucagacacga guacacccac uaccugcagg     1740

ccagauaccu gguggacggc cuguggggcc agggccccuu cuacgagaag aacagacuga     1800

ccugguucga cgagggcacc gccgaguucu ucgccggcag caccagaacc agcggcgugc     1860

ugcccagaaa gagcauccug ggcuaccugg ccaaggacaa gguggaccac agauacagcc     1920

ugaagaagac ccugaacagc ggcuacgacg acagcgacug gauguucuac aacuacggcu     1980

ucgccguggc ccacuaccug uacgagaagg acaugcccac cuucaucaag augaacaagg     2040

ccauccugaa caccgacgug aagagcuacg acgagaucau caagaagcug agcgacgacg     2100

ccaacaagaa caccgaguac cagaaccaca uccaggagcu ggccgacaag uaccagggcg     2160

ccggcauccc ccuggugagc gacgacuacc ugaaggacca cggcuacaag aaggccagcg     2220

agguguacag cgagaucagc aaggccgcca gccugaccaa caccagcgug accgccgaga     2280

agagccagua cuucaacacc uucacccuga gaggcaccua caccggcgag accagcaagg     2340

gcgaguucaa ggacugggac gagaugagca agaagcugga cggcacccug gagagccugg     2400

ccaagaacag cuggagcggc uacaagaccc ugaccgccua cuucaccaac uacagaguga     2460

ccagcgacaa caaggugcag uacgacgugg uguuccacgg cgugcugacc gacaacgccg     2520

acaucagcaa caacaaggcc cccaucgcca aggugaccgg ccccagcacc ggcgccgugg     2580

gcagaaacau cgaguucagc ggcaaggaca gcaaggacga ggacggcaag aucgugagcu     2640

acgacuggga cuucggcgac ggcgccacca gcagaggcaa gaacagcgug cacgccuaca     2700

agaaggccgg caccuacaac gugacccuga aggugaccga cgacaagggc gccaccgcca     2760

ccgagagcuu caccaucgag aucaagaacg aggacaccac cacccccauc accaaggaga     2820

uggagcccaa cgacgacauc aaggaggcca acggccccau cguggagggc gugaccguga     2880

agggcgaccu gaacggcagc gacgacgccg acaccuucua cuucgacgug aaggaggacg     2940

gcgacgugac caucgagcug cccuacagcg gcagcagcaa cuucaccugg cugguguaca     3000

aggagggcga cgaccagaac cacaucgcca gcggcaucga caagaacaac agcaaggugg     3060

gcaccuucaa gagcaccaag ggcagacacu acguguucau cuacaagcac gacagcgcca     3120

gcaacaucag cuacagccug aacaucaagg gccugggcaa cgagaagcug aaggagaagg     3180

agaacaacga cagcagcgac aaggccaccg ugauccccaa cuucaacacc accaugcagg     3240

gcagccugcu gggcgacgac agcagagacu acuacagcuu cgaggugaag gaggagggcg     3300

aggugaacau cgagcuggac aagaaggacg aguucggcgu gaccuggacc cugcaccccg     3360

agagcaacau caacgacaga aucaccuacg gccaggugga cggcaacaag gugagcaaca     3420

aggugaagcu gagacccggc aaguacuacc ugcuggugua caaguacagc ggcagcggca     3480

acuacgagcu gagagugaac aagugaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  4186
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt4)

<400>  4186
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuga agaucauccu gaacagaggc aagaccauga      120

agagaaagug ccugagcaag agacugaugc uggccaucac cauggccacc aucuucaccg      180

ugaacagcac ccugcccauc uacgccgccg uggacaagaa caacgccacc gccgccgugc      240

agaacgagag caagagauac accgugagcu accugaagac ccugaacuac uacgaccugg      300

uggaccugcu ggugaagacc gagaucgaga accugcccga ccuguuccag uacagcagcg      360

acgccaagga guucuacggc aacaagacca gaaugagcuu caucauggac gagaucggca      420

gaagagcccc ccaguacacc gagaucgacc acaagggcau ccccacccug guggaggugg      480

ugagagccgg cuucuaccug ggcuuccaca acaaggagcu gaacgagauc aacaagagaa      540

gcuucaagga gagagugauc cccagcaucc uggccaucca gaagaacccc aacuucaagc      600

ugggcaccga ggugcaggac aagaucguga gcgccaccgg ccugcuggcc ggcaacgaga      660

ccgccccccc cgagguggug aacaacuuca cccccauccu gcaggacugc aucaagaaca      720

ucgacagaua cgcccuggac gaccugaaga gcaaggcccu guucaacgug cuggccgccc      780

ccaccuacga caucaccgag uaccugagag ccaccaagga gaagcccgag aacacccccu      840

gguacggcaa gaucgacggc uucaucaacg agcugaagaa gcuggcccug uacggcaaga      900

ucaacgacaa caacagcugg aucaucgaca acggcaucua ccacaucgcc ccccugggca      960

agcugcacag caacaacaag aucggcaucg agacccugac cgaggugaug aagguguacc     1020

ccuaccugag caugcagcac cugcagagcg ccgaccagau caagagacac uacgacagca     1080

aggacgccga gggcaacaag aucccccugg acaaguucaa gaaggagggc aaggagaagu     1140

acugccccaa gaccuacacc uucgacgacg gcaaggugau caucaaggcc ggcgccagag     1200

uggaggagga gaaggugaag agacuguacu gggccagcaa ggaggugaac agccaguucu     1260

ucagagugua cggcaucgac aagccccugg aggagggcaa ccccgacgac auccugacca     1320

uggugaucua caacagcccc gaggaguaca agcugaacag cgugcuguac ggcuacgaca     1380

ccaacaacgg cggcauguac aucgagcccg agggcaccuu cuucaccuac gagagagagg     1440

cccaggagag caccuacacc cuggaggagc uguucagaca cgaguacacc cacuaccugc     1500

agggcagaua cgccgugccc ggccaguggg gcagaaccaa gcuguacgac aacgacagac     1560

ugaccuggua cgaggagggc ggcgccgagc uguucgccgg cagcaccaga accagcggca     1620

uccugcccag aaagagcauc gugagcaaca uccacaacac caccagaaac aacagauaca     1680

agcugagcga caccgugcac agcaaguacg gcgccagcuu cgaguucuac aacuacgccu     1740

gcauguucau ggacuacaug uacaacaagg acaugggcau ccugaacaag cugaacgacc     1800

uggccaagaa caacgacgug gacggcuacg acaacuacau cagagaccug agcagcaacu     1860

acgcccugaa cgacaaguac caggaccaca ugcaggagag aaucgacaac uacgagaacc     1920

ugaccgugcc cuucguggcc gacgacuacc uggugagaca cgccuacaag aaccccaacg     1980

agaucuacag cgagaucagc gagguggcca agcugaagga cgccaagagc gaggugaaga     2040

agagccagua cuucagcacc uucacccuga gaggcagcua caccggcggc gccagcaagg     2100

gcaagcugga ggaccagaag gccaugaaca aguucaucga cgacagccug aagaagcugg     2160

acaccuacag cuggagcggc uacaagaccc ugaccgccua cuucaccaac uacaaggugg     2220

acagcagcaa cagagugacc uacgacgugg uguuccacgg cuaccugccc aacgagggcg     2280

acagcaagaa cagccugccc uacggcaaga ucaacggcac cuacaagggc accgagaagg     2340

agaagaucaa guucagcagc gagggcagcu ucgaccccga cggcaagauc gugagcuacg     2400

agugggacuu cggcgacggc aacaagagca acgaggagaa ccccgagcac agcuacgaca     2460

aggugggcac cuacaccgug aagcugaagg ugaccgacga caagggcgag agcagcguga     2520

gcaccaccac cgccgagauc aaggaccuga gcgagaacaa gcugcccgug aucuacaugc     2580

acgugcccaa gagcggcgcc cugaaccaga aggugguguu cuacggcaag ggcaccuacg     2640

accccgacgg cagcaucgcc ggcuaccagu gggacuucgg cgacggcagc gacuucagca     2700

gcgagcagaa ccccagccac guguacacca agaagggcga guacaccgug acccugagag     2760

ugauggacag cagcggccag augagcgaga agaccaugaa gaucaagauc accgaccccg     2820

uguaccccau cggcaccgag aaggagccca acaacagcaa ggagaccgcc agcggcccca     2880

ucgugcccgg cauccccgug agcggcacca ucgagaacac cagcgaccag gacuacuucu     2940

acuucgacgu gaucaccccc ggcgagguga agaucgacau caacaagcug ggcuacggcg     3000

gcgccaccug ggugguguac gacgagaaca acaacgccgu gagcuacgcc accgacgacg     3060

gccagaaccu gagcggcaag uucaaggccg acaagcccgg cagauacuac auccaccugu     3120

acauguucaa cggcagcuac augcccuaca gaaucaacau cgagggcagc gugggcagau     3180

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  4187
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt4)

<400>  4187
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagagaaagu gccugagcaa gagacugaug cuggccauca      120

ccauggccac caucuucacc gugaacagca cccugcccau cuacgccgcc guggacaaga      180

acaacgccac cgccgccgug cagaacgaga gcaagagaua caccgugagc uaccugaaga      240

cccugaacua cuacgaccug guggaccugc uggugaagac cgagaucgag aaccugcccg      300

accuguucca guacagcagc gacgccaagg aguucuacgg caacaagacc agaaugagcu      360

ucaucaugga cgagaucggc agaagagccc cccaguacac cgagaucgac cacaagggca      420

uccccacccu gguggaggug gugagagccg gcuucuaccu gggcuuccac aacaaggagc      480

ugaacgagau caacaagaga agcuucaagg agagagugau ccccagcauc cuggccaucc      540

agaagaaccc caacuucaag cugggcaccg aggugcagga caagaucgug agcgccaccg      600

gccugcuggc cggcaacgag accgcccccc ccgagguggu gaacaacuuc acccccaucc      660

ugcaggacug caucaagaac aucgacagau acgcccugga cgaccugaag agcaaggccc      720

uguucaacgu gcuggccgcc cccaccuacg acaucaccga guaccugaga gccaccaagg      780

agaagcccga gaacaccccc ugguacggca agaucgacgg cuucaucaac gagcugaaga      840

agcuggcccu guacggcaag aucaacgaca acaacagcug gaucaucgac aacggcaucu      900

accacaucgc cccccugggc aagcugcaca gcaacaacaa gaucggcauc gagacccuga      960

ccgaggugau gaagguguac cccuaccuga gcaugcagca ccugcagagc gccgaccaga     1020

ucaagagaca cuacgacagc aaggacgccg agggcaacaa gaucccccug gacaaguuca     1080

agaaggaggg caaggagaag uacugcccca agaccuacac cuucgacgac ggcaagguga     1140

ucaucaaggc cggcgccaga guggaggagg agaaggugaa gagacuguac ugggccagca     1200

aggaggugaa cagccaguuc uucagagugu acggcaucga caagccccug gaggagggca     1260

accccgacga cauccugacc auggugaucu acaacagccc cgaggaguac aagcugaaca     1320

gcgugcugua cggcuacgac accaacaacg gcggcaugua caucgagccc gagggcaccu     1380

ucuucaccua cgagagagag gcccaggaga gcaccuacac ccuggaggag cuguucagac     1440

acgaguacac ccacuaccug cagggcagau acgccgugcc cggccagugg ggcagaacca     1500

agcuguacga caacgacaga cugaccuggu acgaggaggg cggcgccgag cuguucgccg     1560

gcagcaccag aaccagcggc auccugccca gaaagagcau cgugagcaac auccacaaca     1620

ccaccagaaa caacagauac aagcugagcg acaccgugca cagcaaguac ggcgccagcu     1680

ucgaguucua caacuacgcc ugcauguuca uggacuacau guacaacaag gacaugggca     1740

uccugaacaa gcugaacgac cuggccaaga acaacgacgu ggacggcuac gacaacuaca     1800

ucagagaccu gagcagcaac uacgcccuga acgacaagua ccaggaccac augcaggaga     1860

gaaucgacaa cuacgagaac cugaccgugc ccuucguggc cgacgacuac cuggugagac     1920

acgccuacaa gaaccccaac gagaucuaca gcgagaucag cgagguggcc aagcugaagg     1980

acgccaagag cgaggugaag aagagccagu acuucagcac cuucacccug agaggcagcu     2040

acaccggcgg cgccagcaag ggcaagcugg aggaccagaa ggccaugaac aaguucaucg     2100

acgacagccu gaagaagcug gacaccuaca gcuggagcgg cuacaagacc cugaccgccu     2160

acuucaccaa cuacaaggug gacagcagca acagagugac cuacgacgug guguuccacg     2220

gcuaccugcc caacgagggc gacagcaaga acagccugcc cuacggcaag aucaacggca     2280

ccuacaaggg caccgagaag gagaagauca aguucagcag cgagggcagc uucgaccccg     2340

acggcaagau cgugagcuac gagugggacu ucggcgacgg caacaagagc aacgaggaga     2400

accccgagca cagcuacgac aaggugggca ccuacaccgu gaagcugaag gugaccgacg     2460

acaagggcga gagcagcgug agcaccacca ccgccgagau caaggaccug agcgagaaca     2520

agcugcccgu gaucuacaug cacgugccca agagcggcgc ccugaaccag aagguggugu     2580

ucuacggcaa gggcaccuac gaccccgacg gcagcaucgc cggcuaccag ugggacuucg     2640

gcgacggcag cgacuucagc agcgagcaga accccagcca cguguacacc aagaagggcg     2700

aguacaccgu gacccugaga gugauggaca gcagcggcca gaugagcgag aagaccauga     2760

agaucaagau caccgacccc guguacccca ucggcaccga gaaggagccc aacaacagca     2820

aggagaccgc cagcggcccc aucgugcccg gcauccccgu gagcggcacc aucgagaaca     2880

ccagcgacca ggacuacuuc uacuucgacg ugaucacccc cggcgaggug aagaucgaca     2940

ucaacaagcu gggcuacggc ggcgccaccu ggguggugua cgacgagaac aacaacgccg     3000

ugagcuacgc caccgacgac ggccagaacc ugagcggcaa guucaaggcc gacaagcccg     3060

gcagauacua cauccaccug uacauguuca acggcagcua caugcccuac agaaucaaca     3120

ucgagggcag cgugggcaga ugaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  4188
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt4)

<400>  4188
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcuguuc cuguucagca      120

gcgccuacag cgugcagaac gagagcaaga gauacaccgu gagcuaccug aagacccuga      180

acuacuacga ccugguggac cugcugguga agaccgagau cgagaaccug cccgaccugu      240

uccaguacag cagcgacgcc aaggaguucu acggcaacaa gaccagaaug agcuucauca      300

uggacgagau cggcagaaga gccccccagu acaccgagau cgaccacaag ggcaucccca      360

cccuggugga gguggugaga gccggcuucu accugggcuu ccacaacaag gagcugaacg      420

agaucaacaa gagaagcuuc aaggagagag ugauccccag cauccuggcc auccagaaga      480

accccaacuu caagcugggc accgaggugc aggacaagau cgugagcgcc accggccugc      540

uggccggcaa cgagaccgcc ccccccgagg uggugaacaa cuucaccccc auccugcagg      600

acugcaucaa gaacaucgac agauacgccc uggacgaccu gaagagcaag gcccuguuca      660

acgugcuggc cgcccccacc uacgacauca ccgaguaccu gagagccacc aaggagaagc      720

ccgagaacac ccccugguac ggcaagaucg acggcuucau caacgagcug aagaagcugg      780

cccuguacgg caagaucaac gacaacaaca gcuggaucau cgacaacggc aucuaccaca      840

ucgccccccu gggcaagcug cacagcaaca acaagaucgg caucgagacc cugaccgagg      900

ugaugaaggu guaccccuac cugagcaugc agcaccugca gagcgccgac cagaucaaga      960

gacacuacga cagcaaggac gccgagggca acaagauccc ccuggacaag uucaagaagg     1020

agggcaagga gaaguacugc cccaagaccu acaccuucga cgacggcaag gugaucauca     1080

aggccggcgc cagaguggag gaggagaagg ugaagagacu guacugggcc agcaaggagg     1140

ugaacagcca guucuucaga guguacggca ucgacaagcc ccuggaggag ggcaaccccg     1200

acgacauccu gaccauggug aucuacaaca gccccgagga guacaagcug aacagcgugc     1260

uguacggcua cgacaccaac aacggcggca uguacaucga gcccgagggc accuucuuca     1320

ccuacgagag agaggcccag gagagcaccu acacccugga ggagcuguuc agacacgagu     1380

acacccacua ccugcagggc agauacgccg ugcccggcca guggggcaga accaagcugu     1440

acgacaacga cagacugacc ugguacgagg agggcggcgc cgagcuguuc gccggcagca     1500

ccagaaccag cggcauccug cccagaaaga gcaucgugag caacauccac aacaccacca     1560

gaaacaacag auacaagcug agcgacaccg ugcacagcaa guacggcgcc agcuucgagu     1620

ucuacaacua cgccugcaug uucauggacu acauguacaa caaggacaug ggcauccuga     1680

acaagcugaa cgaccuggcc aagaacaacg acguggacgg cuacgacaac uacaucagag     1740

accugagcag caacuacgcc cugaacgaca aguaccagga ccacaugcag gagagaaucg     1800

acaacuacga gaaccugacc gugcccuucg uggccgacga cuaccuggug agacacgccu     1860

acaagaaccc caacgagauc uacagcgaga ucagcgaggu ggccaagcug aaggacgcca     1920

agagcgaggu gaagaagagc caguacuuca gcaccuucac ccugagaggc agcuacaccg     1980

gcggcgccag caagggcaag cuggaggacc agaaggccau gaacaaguuc aucgacgaca     2040

gccugaagaa gcuggacacc uacagcugga gcggcuacaa gacccugacc gccuacuuca     2100

ccaacuacaa gguggacagc agcaacagag ugaccuacga cgugguguuc cacggcuacc     2160

ugcccaacga gggcgacagc aagaacagcc ugcccuacgg caagaucaac ggcaccuaca     2220

agggcaccga gaaggagaag aucaaguuca gcagcgaggg cagcuucgac cccgacggca     2280

agaucgugag cuacgagugg gacuucggcg acggcaacaa gagcaacgag gagaaccccg     2340

agcacagcua cgacaaggug ggcaccuaca ccgugaagcu gaaggugacc gacgacaagg     2400

gcgagagcag cgugagcacc accaccgccg agaucaagga ccugagcgag aacaagcugc     2460

ccgugaucua caugcacgug cccaagagcg gcgcccugaa ccagaaggug guguucuacg     2520

gcaagggcac cuacgacccc gacggcagca ucgccggcua ccagugggac uucggcgacg     2580

gcagcgacuu cagcagcgag cagaacccca gccacgugua caccaagaag ggcgaguaca     2640

ccgugacccu gagagugaug gacagcagcg gccagaugag cgagaagacc augaagauca     2700

agaucaccga ccccguguac cccaucggca ccgagaagga gcccaacaac agcaaggaga     2760

ccgccagcgg ccccaucgug cccggcaucc ccgugagcgg caccaucgag aacaccagcg     2820

accaggacua cuucuacuuc gacgugauca cccccggcga ggugaagauc gacaucaaca     2880

agcugggcua cggcggcgcc accugggugg uguacgacga gaacaacaac gccgugagcu     2940

acgccaccga cgacggccag aaccugagcg gcaaguucaa ggccgacaag cccggcagau     3000

acuacaucca ccuguacaug uucaacggca gcuacaugcc cuacagaauc aacaucgagg     3060

gcagcguggg cagaugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4189
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt4)

<400>  4189
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcuguuc cuguucagca      120

gcgccuacag caugaagaga aagugccuga gcaagagacu gaugcuggcc aucaccaugg      180

ccaccaucuu caccgugaac agcacccugc ccaucuacgc cgccguggac aagaacaacg      240

ccaccgccgc cagaagaaga agaaagagag ugcagaacga gagcaagaga uacaccguga      300

gcuaccugaa gacccugaac uacuacgacc ugguggaccu gcuggugaag accgagaucg      360

agaaccugcc cgaccuguuc caguacagca gcgacgccaa ggaguucuac ggcaacaaga      420

ccagaaugag cuucaucaug gacgagaucg gcagaagagc cccccaguac accgagaucg      480

accacaaggg cauccccacc cugguggagg uggugagagc cggcuucuac cugggcuucc      540

acaacaagga gcugaacgag aucaacaaga gaagcuucaa ggagagagug auccccagca      600

uccuggccau ccagaagaac cccaacuuca agcugggcac cgaggugcag gacaagaucg      660

ugagcgccac cggccugcug gccggcaacg agaccgcccc ccccgaggug gugaacaacu      720

ucacccccau ccugcaggac ugcaucaaga acaucgacag auacgcccug gacgaccuga      780

agagcaaggc ccuguucaac gugcuggccg cccccaccua cgacaucacc gaguaccuga      840

gagccaccaa ggagaagccc gagaacaccc ccugguacgg caagaucgac ggcuucauca      900

acgagcugaa gaagcuggcc cuguacggca agaucaacga caacaacagc uggaucaucg      960

acaacggcau cuaccacauc gccccccugg gcaagcugca cagcaacaac aagaucggca     1020

ucgagacccu gaccgaggug augaaggugu accccuaccu gagcaugcag caccugcaga     1080

gcgccgacca gaucaagaga cacuacgaca gcaaggacgc cgagggcaac aagauccccc     1140

uggacaaguu caagaaggag ggcaaggaga aguacugccc caagaccuac accuucgacg     1200

acggcaaggu gaucaucaag gccggcgcca gaguggagga ggagaaggug aagagacugu     1260

acugggccag caaggaggug aacagccagu ucuucagagu guacggcauc gacaagcccc     1320

uggaggaggg caaccccgac gacauccuga ccauggugau cuacaacagc cccgaggagu     1380

acaagcugaa cagcgugcug uacggcuacg acaccaacaa cggcggcaug uacaucgagc     1440

ccgagggcac cuucuucacc uacgagagag aggcccagga gagcaccuac acccuggagg     1500

agcuguucag acacgaguac acccacuacc ugcagggcag auacgccgug cccggccagu     1560

ggggcagaac caagcuguac gacaacgaca gacugaccug guacgaggag ggcggcgccg     1620

agcuguucgc cggcagcacc agaaccagcg gcauccugcc cagaaagagc aucgugagca     1680

acauccacaa caccaccaga aacaacagau acaagcugag cgacaccgug cacagcaagu     1740

acggcgccag cuucgaguuc uacaacuacg ccugcauguu cauggacuac auguacaaca     1800

aggacauggg cauccugaac aagcugaacg accuggccaa gaacaacgac guggacggcu     1860

acgacaacua caucagagac cugagcagca acuacgcccu gaacgacaag uaccaggacc     1920

acaugcagga gagaaucgac aacuacgaga accugaccgu gcccuucgug gccgacgacu     1980

accuggugag acacgccuac aagaacccca acgagaucua cagcgagauc agcgaggugg     2040

ccaagcugaa ggacgccaag agcgagguga agaagagcca guacuucagc accuucaccc     2100

ugagaggcag cuacaccggc ggcgccagca agggcaagcu ggaggaccag aaggccauga     2160

acaaguucau cgacgacagc cugaagaagc uggacaccua cagcuggagc ggcuacaaga     2220

cccugaccgc cuacuucacc aacuacaagg uggacagcag caacagagug accuacgacg     2280

ugguguucca cggcuaccug cccaacgagg gcgacagcaa gaacagccug cccuacggca     2340

agaucaacgg caccuacaag ggcaccgaga aggagaagau caaguucagc agcgagggca     2400

gcuucgaccc cgacggcaag aucgugagcu acgaguggga cuucggcgac ggcaacaaga     2460

gcaacgagga gaaccccgag cacagcuacg acaagguggg caccuacacc gugaagcuga     2520

aggugaccga cgacaagggc gagagcagcg ugagcaccac caccgccgag aucaaggacc     2580

ugagcgagaa caagcugccc gugaucuaca ugcacgugcc caagagcggc gcccugaacc     2640

agaagguggu guucuacggc aagggcaccu acgaccccga cggcagcauc gccggcuacc     2700

agugggacuu cggcgacggc agcgacuuca gcagcgagca gaaccccagc cacguguaca     2760

ccaagaaggg cgaguacacc gugacccuga gagugaugga cagcagcggc cagaugagcg     2820

agaagaccau gaagaucaag aucaccgacc ccguguaccc caucggcacc gagaaggagc     2880

ccaacaacag caaggagacc gccagcggcc ccaucgugcc cggcaucccc gugagcggca     2940

ccaucgagaa caccagcgac caggacuacu ucuacuucga cgugaucacc cccggcgagg     3000

ugaagaucga caucaacaag cugggcuacg gcggcgccac cuggguggug uacgacgaga     3060

acaacaacgc cgugagcuac gccaccgacg acggccagaa ccugagcggc aaguucaagg     3120

ccgacaagcc cggcagauac uacauccacc uguacauguu caacggcagc uacaugcccu     3180

acagaaucaa caucgagggc agcgugggca gaugaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  4190
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt4)

<400>  4190
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccugcug ggcgccgccu      120

ucgccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagagca ucagaccccc cuaccccagc uacggcuacg      240

agcccauggg cggcuggcug caccaccaga ucauccccgu gcugagccag cagcaccccc      300

ccacccacac ccugcagccc caccaccaca uccccguggu gcccgcccag cagcccguga      360

ucccccagca gcccaugaug cccgugcccg gccagcacag caugaccccc auccagcacc      420

accagcccaa ccugcccccc cccgcccagc agcccuacca gccccagccc gugcagcccc      480

agccccacca gcccaugcag ccccagcccc ccgugcaccc caugcagccc cugccccccc      540

agcccccccu gccccccaug uuccccaugc agccccugcc ccccaugcug cccgaccuga      600

cccuggaggc cuggcccagc accgacaaga ccaagagaga ggagguggac ugaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  4191
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt4)

<400>  4191
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagag caucagaccc cccuacccca      180

gcuacggcua cgagcccaug ggcggcuggu gaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  4192
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt4)

<400>  4192
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagag caucagaccc ccccccaugc      180

ugcccgaccu gacccuggag gccuggccca gcaccgacaa gaccaagaga gaggaggugg      240

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  4193
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt4)

<400>  4193
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cccccagaac ccuggugcug cugcugagcg      120

gcgcccuggc ccugacccag accugggcca ugccccugcc cccccacccc ggccaccccg      180

gcuacaucaa cuucagcuac gaggugcuga ccccccugaa gugguaccag agcaucagac      240

cccccuaccc cagcuacggc uacgagccca ugggcggcug gugaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  4194
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt4)

<400>  4194
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cccccagaac ccuggugcug cugcugagcg      120

gcgcccuggc ccugacccag accugggcca ugccccugcc cccccacccc ggccaccccg      180

gcuacaucaa cuucagcuac gaggugcuga ccccccugaa gugguaccag agcaucagac      240

ccccccccau gcugcccgac cugacccugg aggccuggcc cagcaccgac aagaccaaga      300

gagaggaggu ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  4195
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt4)

<400>  4195
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuggug ggcgccgccu      120

ucgccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagagca ugaucagacc ccccuacagc agcuacggcu      240

acgagcccau gggcggcugg cugcaccacc agaucauccc cguggugagc cagcagcacc      300

cccugaccca cacccugcag agccaccacc acauccccgu ggugcccgcc cagcagccca      360

gagugagaca gcaggcccug augcccgugc ccggccagca gagcaugacc cccacccagc      420

accaccagcc caaccugccc cugcccgccc agcagcccuu ccagccccag cccgugcagc      480

cccagcccca ccagcccaug cagccccagc cccccgugca gcccaugcag ccccugcugc      540

cccagccccc ccugcccccc auguuccccc ugagaccccu gccccccauc cugcccgacc      600

ugcaccugga ggccuggccc gccaccgaca agaccaagca ggaggaggug gacugaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  4196
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt4)

<400>  4196
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagag caugaucaga ccccccuaca      180

gcagcuacgg cuacgagccc augggcggcu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4197
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt4)

<400>  4197
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagag caugaucaga ccccccccca      180

uccugcccga ccugcaccug gaggccuggc ccgccaccga caagaccaag caggaggagg      240

uggacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4198
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt4)

<400>  4198
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cccccagaac ccuggugcug cugcugagcg      120

gcgcccuggc ccugacccag accugggcca ugccccugcc cccccacccc ggccaccccg      180

gcuacaucaa cuucagcuac gaggugcuga ccccccugaa gugguaccag agcaugauca      240

gaccccccua cagcagcuac ggcuacgagc ccaugggcgg cuggugagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4199
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt4)

<400>  4199
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cccccagaac ccuggugcug cugcugagcg      120

gcgcccuggc ccugacccag accugggcca ugccccugcc cccccacccc ggccaccccg      180

gcuacaucaa cuucagcuac gaggugcuga ccccccugaa gugguaccag agcaugauca      240

gacccccccc cauccugccc gaccugcacc uggaggccug gcccgccacc gacaagacca      300

agcaggagga gguggacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4200
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt4)

<400>  4200
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccugcug ggcgccgccu      120

ucagcaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccuacacc agcuacggcu      240

acgagcccau gggcggcugg cugcaccacc agaucauccc cguggugagc cagcagaccc      300

cccagagcca cgcccugcag ccccaccacc acauccccau ggugcccgcc cagcagcccg      360

gcauccccca gcagcccaug augccccugc ccggccagca cagcaugacc cccacccagc      420

accaccagcc caaccugccc cugcccgccc agcagcccuu ccagccccag cccgugcagc      480

cccagcccca ccagccccug cagccccaga gccccaugca ccccauccag ccccugcugc      540

cccagccccc ccugcccccc auguucagca ugcagagccu gcugcccgac cugccccugg      600

aggccuggcc cgccaccgac aagaccaaga gagaggaggu ggacugagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4201
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt4)

<400>  4201
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagaa caugaucaga caccccuaca      180

ccagcuacgg cuacgagccc augggcggcu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4202
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt4)

<400>  4202
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagaa caugaucaga caccccagcc      180

ugcugcccga ccugccccug gaggccuggc ccgccaccga caagaccaag agagaggagg      240

uggacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4203
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt4)

<400>  4203
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cccccagaac ccuggugcug cugcugagcg      120

gcgcccuggc ccugacccag accugggcca ugccccugcc cccccacccc ggccaccccg      180

gcuacaucaa cuucagcuac gaggugcuga ccccccugaa gugguaccag aacaugauca      240

gacaccccua caccagcuac ggcuacgagc ccaugggcgg cuggugagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4204
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt4)

<400>  4204
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cccccagaac ccuggugcug cugcugagcg      120

gcgcccuggc ccugacccag accugggcca ugccccugcc cccccacccc ggccaccccg      180

gcuacaucaa cuucagcuac gaggugcuga ccccccugaa gugguaccag aacaugauca      240

gacaccccag ccugcugccc gaccugcccc uggaggccug gcccgccacc gacaagacca      300

agagagagga gguggacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4205
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt4)

<400>  4205
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccugcug ggcgccgccu      120

ucagcaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacauca      180

gacaccccua caccagcuac ggcuacgagc ccaugggcgg cuggcugcac caccagauca      240

uccccguggu gagccagcag accccccaga gccacgcccu gcagccccac caccacaucc      300

ccauggugcc cgcccagcag cccggcaucc cccagcagcc caugaugccc cugcccggcc      360

agcacagcau gacccccacc cagcaccacc agcccaaccu gccccugccc gcccagcagc      420

ccuuccagcc ccagcccgug cagccccagc cccaccagcc ccugcagccc cagagcccca      480

ugcaccccau ccagccccug cugccccagc ccccccugcc ccccauguuc agcaugcaga      540

gccugcugcc cgaccugccc cuggaggccu ggcccgccac cgacaagacc aagagagagg      600

agguggacug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  4206
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt4)

<400>  4206
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuucgc cugccugcug ggcgccagcc      120

uggccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccuacacc agcuacggcu      240

acgagcccau gggcggcugg cugcaccacc agaucauccc cguggugagc cagcagaccc      300

cccagagcca cgcccugcag ccccaccacc acauccccau ggugcccgcc cagcagcccg      360

gcauccccca gcagcccaug augccccugc ccggccagca cagcaugacc cccacccagc      420

accaccagcc caaccugccc cugcccgccc agcagcccuu ccagccccag cccgugcagc      480

cccagcccca ccagccccug cagccccaga gccccaugca ccccauccag ccccugcugc      540

cccagccccc ccugcccccc auguucagca ugcagagccu gcugcccgac cugccccugg      600

aggccuggcc cgccaccgac aagaccaaga gagaggaggu ggacugagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4207
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt4)

<400>  4207
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccugcug ggcgccgccu      120

ucagcaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccagccug cugcccgacc      240

ugccccugga ggccuggccc gccaccgaca agaccaagag agaggaggug gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  4208
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt4)

<400>  4208
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccugcug ggcgccgccu      120

ucagcaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

accuguaccu ggaggccauc agaaucgaca gaaccgccuu cgugcugacc ccccugaagu      240

gguaccagaa caugaucaga caccccuaca ccagcuacgg cuacgagccc augggcggcu      300

ggcugcacca ccagaucauc cccgugguga gccagcagac cccccagagc cacgcccugc      360

agccccacca ccacaucccc auggugcccg cccagcagcc cggcaucccc cagcagccca      420

ugaugccccu gcccggccag cacagcauga cccccaccca gcaccaccag cccaaccugc      480

cccugcccgc ccagcagccc uuccagcccc agcccgugca gccccagccc caccagcccc      540

ugcagcccca gagccccaug caccccaucc agccccugcu gccccagccc ccccugcccc      600

ccauguucag caugcagagc cugcugcccg accugccccu ggaggccugg cccgccaccg      660

acaagaccaa gagagaggag guggacugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  4209
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt4)

<400>  4209
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccugcug ggcgccgccu      120

ucagcaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccaccccc cagagccacg      240

cccugcagcc ccaccaccac auccccaugg ugcccgccca gcagcccggc aucccccagc      300

agcccaugau gccccugccc ggccagcaca gcaugacccc cacccagcac caccagccca      360

accugccccu gcccgcccag cagcccuucc agccccagcc cgugcagccc cagccccacc      420

agccccugca gccccagagc cccaugcacc ccauccagcc ccugcugccc cagccccccc      480

ugccccccau guucagcaug cagagccugc ugcccgaccu gccccuggag gccuggcccg      540

ccaccgacaa gaccaagaga gaggaggugg acugaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  4210
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt4)

<400>  4210
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagaa caugaucaga caccccuaca      180

ccagcuacgg cuacgagccc augggcggcu ggcugcacca ccagaucauc cccgugguga      240

gccagcagac cccccagagc cacgcccugc agccccacca ccacaucccc auggugcccg      300

cccagcagcc cggcaucccc cagcagccca ugaugccccu gcccggccag cacagcauga      360

cccccaccca gcaccaccag cccaaccugc cccugcccgc ccagcagccc uuccagcccc      420

agcccgugca gccccagccc caccagcccc ugcagcccca gagccccaug caccccaucc      480

agccccugcu gccccagccc ccccugcccc ccauguucag caugcagagc cugcugcccg      540

accugccccu ggaggccugg cccgccaccg acaagaccaa gagagaggag guggacugag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  4211
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt4)

<400>  4211
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg ccagacugcc ccugcugcug ggccugcugc      120

ugcugcccag acccggcaga ccccuggacc uggccgacua caccuacgac cuggccgagg      180

aggacgacag cgagccccug aacuacaagg accccugcaa ggccgccgcc uuccugggcg      240

acaucgcccu ggacgaggag gaccugagag ccuuccaggu gcagcaggcc guggaccuga      300

gaagacacac cgccagaaag agcagcauca aggccgccgu gcccggcaac accagcaccc      360

ccagcugcca gagcaccaac ggccagcccc agagaggcgc cugcggcaga uggagaggca      420

gaagcagaag cagaagagcc gccaccagca gacccgagag aguguggccc gacggcguga      480

uccccuucgu gaucggcggc aacuucaccg gcagccagag agccguguuc agacaggcca      540

ugagacacug ggagaagcac accugcguga ccuuccugga gagaaccgac gaggacagcu      600

acaucguguu caccuacaga cccugcggcu gcugcagcua cgugggcaga agaggcggcg      660

gcccccaggc caucagcauc ggcaagaacu gcgacaaguu cggcaucgug gugcacgagc      720

ugggccacgu ggugggcuuc uggcacgagc acaccagacc cgacagagac agacacguga      780

gcaucgugag agagaacauc cagcccggcc aggaguacaa cuuccugaag auggagcccc      840

aggaggugga gagccugggc gagaccuacg acuucgacag caucaugcac uacgccagaa      900

acaccuucag cagaggcauc uuccuggaca ccaucgugcc caaguacgag gugaacggcg      960

ugaagccccc caucggccag agaaccagac ugagcaaggg cgacaucgcc caggccagaa     1020

agcuguacaa gugccccgcc ugcggcgaga cccugcagga cagcaccggc aacuucagca     1080

gccccgagua ccccaacggc uacagcgccc acaugcacug cguguggaga aucagcguga     1140

cccccggcga gaagaucauc cugaacuuca ccagccugga ccuguacaga agcagacugu     1200

gcugguacga cuacguggag gugagagacg gcuucuggag aaaggccccc cugagaggca     1260

gauucugcgg cagcaagcug cccgagccca ucgugagcac cgacagcaga cugugggugg     1320

aguucagaag cagcagcaac ugggugggca agggcuucuu cgccguguac gaggccaucu     1380

gcggcggcga cgugaagaag gacuacggcc acauccagag ccccaacuac cccgacgacu     1440

acagacccag caaggugugc aucuggagaa uccaggugag cgagggcuuc cacgugggcc     1500

ugaccuucca gagcuucgag aucgagagac acgacagcug cgccuacgac uaccuggagg     1560

ugagagacgg ccacagcgag agcagcaccc ugaucggcag auacugcggc uacgagaagc     1620

ccgacgacau caagagcacc agcagcagac uguggcugaa guucgugagc gacggcagca     1680

ucaacaaggc cggcuucgcc gugaacuucu ucaaggaggu ggacgagugc agcagaccca     1740

acagaggcgg cugcgagcag agaugccuga acacccuggg cagcuacaag ugcagcugcg     1800

accccggcua cgagcuggcc cccgacaaga gaagaugcga ggccgccugc ggcggcuucc     1860

ugaccaagcu gaacggcagc aucaccagcc ccggcuggcc caaggaguac ccccccaaca     1920

agaacugcau cuggcagcug guggccccca cccaguacag aaucagccug caguucgacu     1980

ucuucgagac cgagggcaac gacgugugca aguacgacuu cguggaggug agaagcggcc     2040

ugaccgccga cagcaagcug cacggcaagu ucugcggcag cgagaagccc gaggugauca     2100

ccagccagua caacaacaug agaguggagu ucaagagcga caacaccgug agcaagaagg     2160

gcuucaaggc ccacuucuuc agcgacaagg acgagugcag caaggacaac ggcggcugcc     2220

agcaggacug cgugaacacc uucggcagcu acgagugcca gugcagaagc ggcuucgugc     2280

ugcacgacaa caagcacgac ugcaaggagg ccggcugcga ccacaaggug accagcacca     2340

gcggcaccau caccagcccc aacuggcccg acaaguaccc cagcaagaag gagugcaccu     2400

gggccaucag cagcaccccc ggccacagag ugaagcugac cuucauggag auggacaucg     2460

agagccagcc cgagugcgcc uacgaccacc uggagguguu cgacggcaga gacgccaagg     2520

cccccgugcu gggcagauuc ugcggcagca agaagcccga gcccgugcug gccaccggca     2580

gcagaauguu ccugagauuc uacagcgaca acagcgugca gagaaagggc uuccaggcca     2640

gccacgccac cgagugcggc ggccagguga gagccgacgu gaagaccaag gaccuguaca     2700

gccacgccca guucggcgac aacaacuacc ccggcggcgu ggacugcgag ugggugaucg     2760

uggccgagga gggcuacggc guggagcugg uguuccagac cuucgaggug gaggaggaga     2820

ccgacugcgg cuacgacuac auggagcugu ucgacggcua cgacagcacc gcccccagac     2880

ugggcagaua cugcggcagc ggcccccccg aggaggugua cagcgccggc gacagcgugc     2940

uggugaaguu ccacagcgac gacaccauca ccaagaaggg cuuccaccug agauacacca     3000

gcaccaaguu ccaggacacc cugcacagca gaaagugagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  4212
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt4)

<400>  4212
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggca ccagaugccu gcuggcccug cugcugcccc      120

aggugcugcu gggcggcgcc gccggccugg ugcccgagcu gggcagaaga aaguucgccg      180

ccgccagcag cggcagaccc agcagccagc ccagcgacga ggugcugagc gaguucgagc      240

ugagacugcu gagcauguuc ggccugaagc agagacccac ccccagcaga gacgccgugg      300

ugccccccua caugcuggac cuguacagaa gacacagcgg ccagcccggc agccccgccc      360

ccgaccacag acuggagaga gccgccagca gagccaacac cgugagaagc uuccaccacg      420

aggagagccu ggaggagcug cccgagacca gcggcaagac caccagaaga uucuucuuca      480

accugagcag cauccccacc gaggaguuca ucaccagcgc cgagcugcag guguucagag      540

agcagaugca ggacgcccug ggcaacaaca gcagcuucca ccacagaauc aacaucuacg      600

agaucaucaa gcccgccacc gccaacagca aguuccccgu gaccagacug cuggacacca      660

gacuggugaa ccagaacgcc agcagauggg agagcuucga cgugaccccc gccgugauga      720

gauggaccgc ccagggccac gccaaccacg gcuucguggu ggagguggcc caccuggagg      780

agaagcaggg cgugagcaag agacacguga gaaucagcag aagccugcac caggacgagc      840

acagcuggag ccagaucaga ccccugcugg ugaccuucgg ccacgacggc aagggccacc      900

cccugcacaa gagagagaag agacaggcca agcacaagca gagaaagaga cugaagagca      960

gcugcaagag acacccccug uacguggacu ucagcgacgu gggcuggaac gacuggaucg     1020

uggccccccc cggcuaccac gccuucuacu gccacggcga gugccccuuc ccccuggccg     1080

accaccugaa cagcaccaac cacgccaucg ugcagacccu ggugaacagc gugaacagca     1140

agauccccaa ggccugcugc gugcccaccg agcugagcgc caucagcaug cuguaccugg     1200

acgagaacga gaagguggug cugaagaacu accaggacau ggugguggag ggcugcggcu     1260

gcagaugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  4213
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt4)

<400>  4213
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auccccggca acagaaugcu gaugguggug cugcugugcc      120

aggugcugcu gggcggcgcc agccacgcca gccugauccc cgagaccggc aagaagaagg      180

uggccgagau ccagggccac gccggcggca gaagaagcgg ccagagccac gagcugcuga      240

gagacuucga ggccacccug cugcagaugu ucggccugag aagaagaccc cagcccagca      300

agagcgccgu gauccccgac uacaugagag accuguacag acugcagagc ggcgaggagg      360

aggaggagca gauccacagc accggccugg aguaccccga gagacccgcc agcagagcca      420

acaccgugag aagcuuccac cacgaggagc accuggagaa cauccccggc accagcgaga      480

acagcgccuu cagauuccug uucaaccuga gcagcauccc cgagaacgag gugaucagca      540

gcgccgagcu gagacuguuc agagagcagg uggaccaggg ccccgacugg gagagaggcu      600

uccacagaau caacaucuac gaggugauga agccccccgc cgagguggug cccggccacc      660

ugaucaccag acugcuggac accagacugg ugcaccacaa cgugaccaga ugggagaccu      720

ucgacgugag ccccgccgug cugagaugga ccagagagaa gcagcccaac uacggccugg      780

ccaucgaggu gacccaccug caccagacca gaacccacca gggccagcac gugagaauca      840

gcagaagccu gccccagggc agcggcaacu gggcccagcu gagaccccug cuggugaccu      900

ucggccacga cggcagaggc cacgcccuga ccagaagaag aagagccaag agaagcccca      960

agcaccacag ccagagagcc agaaagaaga acaagaacug cagaagacac agccuguacg     1020

uggacuucag cgacgugggc uggaacgacu ggaucguggc cccccccggc uaccaggccu     1080

ucuacugcca cggcgacugc cccuuccccc uggccgacca ccugaacagc accaaccacg     1140

ccaucgugca gacccuggug aacagcguga acagcagcau ccccaaggcc ugcugcgugc     1200

ccaccgagcu gagcgccauc agcaugcugu accuggacga guacgacaag guggugcuga     1260

agaacuacca ggagauggug guggagggcu gcggcugcag augaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  4214
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt4)

<400>  4214
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggccugg gcagaagagc ccaguggcug ugcugguggu      120

ggggccugcu gugcagcugc ugcggccccc ccccccugag acccccccug cccgccgccg      180

ccgccgccgc cgccggcggc cagcugcugg gcgacggcgg cagccccggc agaaccgagc      240

agcccccccc cagcccccag agcagcagcg gcuuccugua cagaagacug aagacccagg      300

agaagagaga gaugcagaag gagauccuga gcgugcuggg ccugccccac agacccagac      360

cccugcacgg ccugcagcag ccccagcccc ccgcccugag acagcaggag gagcagcagc      420

agcagcagca gcugcccaga ggcgagcccc cccccggcag acugaagagc gccccccugu      480

ucaugcugga ccuguacaac gcccugagcg ccgacaacga cgaggacggc gccagcgagg      540

gcgagagaca gcagagcugg ccccacgagg ccgccagcag cagccagaga agacagcccc      600

cccccggcgc cgcccacccc cugaacagaa agagccugcu ggcccccggc agcggcagcg      660

gcggcgccag cccccugacc agcgcccagg acagcgccuu ccugaacgac gccgacaugg      720

ugaugagcuu cgugaaccug guggaguacg acaaggaguu cagccccaga cagagacacc      780

acaaggaguu caaguucaac cugagccaga uccccgaggg cgagguggug accgccgccg      840

aguucagaau cuacaaggac ugcgugaugg gcagcuucaa gaaccagacc uuccugauca      900

gcaucuacca ggugcugcag gagcaccagc acagagacag cgaccuguuc cugcuggaca      960

ccagaguggu gugggccagc gaggagggcu ggcuggaguu cgacaucacc gccaccagca     1020

accugugggu ggugaccccc cagcacaaca ugggccugca gcugagcgug gugaccagag     1080

acggcgugca cgugcacccc agagccgccg gccugguggg cagagacggc cccuacgaca     1140

agcagcccuu caugguggcc uucuucaagg ugagcgaggu gcacgugaga accaccagaa     1200

gcgccagcag cagaagaaga cagcagagca gaaacagaag cacccagagc caggacgugg     1260

ccagagugag cagcgccagc gacuacaaca gcagcgagcu gaagaccgcc ugcagaaagc     1320

acgagcugua cgugagcuuc caggaccugg gcuggcagga cuggaucauc gcccccaagg     1380

gcuacgccgc caacuacugc gacggcgagu gcagcuuccc ccugaacgcc cacaugaacg     1440

ccaccaacca cgccaucgug cagacccugg ugcaccugau gaaccccgag uacgugccca     1500

agcccugcug cgcccccacc aagcugaacg ccaucagcgu gcuguacuuc gacgacaaca     1560

gcaacgugau ccugaagaag uacagaaaca ugguggugag agccugcggc ugccacugag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  4215
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt4)

<400>  4215
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugagaa gccugagagc cgccgccccc cacagcuucg      120

uggcccugug ggccccccug uuccugcuga gaagcgcccu ggccgacuuc agccuggaca      180

acgaggugca cagcagcuuc auccacagaa gacugagaag ccaggagaga agagagaugc      240

agagagagau ccugagcauc cugggccugc cccacagacc cagaccccac cugcagggca      300

agcacaacag cgcccccaug uucaugcugg accuguacaa cgccauggcc guggaggagg      360

gcggcggccc cggcggccag ggcuucagcu accccuacaa ggccguguuc agcacccagg      420

gccccccccu ggccagccug caggacagcc acuuccugac cgacgccgac auggugauga      480

gcuucgugaa ccugguggag cacgacaagg aguucuucca ccccagauac caccacagag      540

aguucagauu cgaccugagc aagauccccg agggcgaggc cgugaccgcc gccgaguuca      600

gaaucuacaa ggacuacauc agagagagau ucgacaacga gaccuucaga aucagcgugu      660

accaggugcu gcaggagcac cugggcagag agagcgaccu guuccugcug gacagcagaa      720

cccugugggc cagcgaggag ggcuggcugg uguucgacau caccgccacc agcaaccacu      780

ggguggugaa ccccagacac aaccugggcc ugcagcugag cguggagacc cuggacggcc      840

agagcaucaa ccccaagcug gccggccuga ucggcagaca cggcccccag aacaagcagc      900

ccuucauggu ggccuucuuc aaggccaccg aggugcacuu cagaagcauc agaagcaccg      960

gcagcaagca gagaagccag aacagaagca agacccccaa gaaccaggag gcccugagaa     1020

uggccaacgu ggccgagaac agcagcagcg accagagaca ggccugcaag aagcacgagc     1080

uguacgugag cuucagagac cugggcuggc aggacuggau caucgccccc gagggcuacg     1140

ccgccuacua cugcgagggc gagugcgccu ucccccugaa cagcuacaug aacgccacca     1200

accacgccau cgugcagacc cuggugcacu ucaucaaccc cgagaccgug cccaagcccu     1260

gcugcgcccc cacccagcug aacgccauca gcgugcugua cuucgacgac agcagcaacg     1320

ugauccugaa gaaguacaga aacauggugg ugagagccug cggcugccac ugaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  4216
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt4)

<400>  4216
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggccagcg ccgcccugcu gugccugcug cugaccgccg      120

ccgccuucag cccccagggc cuggcccagc ccgugggcau caacaccagc accaccugcu      180

gcuacagauu caucaacaag aagaucccca agcagagacu ggagagcuac agaagaacca      240

ccagcagcca cugccccaga gaggccguga ucuucaagac caagcuggac aaggagaucu      300

gcgccgaccc cacccagaag ugggugcagg acuucaugaa gcaccuggac aagaagaccc      360

agacccccaa gcugugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  4217
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt4)

<400>  4217
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcugaccc ugaucauccu gcugcccgug gugagcaagu      120

ucagcuucgu gagccugagc gccccccagc acuggagcug ccccgagggc acccuggccg      180

gcaacggcaa cagcaccugc gugggccccg cccccuuccu gaucuucagc cacggcaaca      240

gcaucuucag aaucgacacc gagggcacca acuacgagca gcugguggug gacgccggcg      300

ugagcgugau cauggacuuc cacuacaacg agaagagaau cuacugggug gaccuggaga      360

gacagcugcu gcagagagug uuccugaacg gcagcagaca ggagagagug ugcaacaucg      420

agaagaacgu gagcggcaug gccaucaacu ggaucaacga ggaggugauc uggagcaacc      480

agcaggaggg caucaucacc gugaccgaca ugaagggcaa caacagccac auccugcuga      540

gcgcccugaa guaccccgcc aacguggccg uggaccccgu ggagagauuc aucuucugga      600

gcagcgaggu ggccggcagc cuguacagag ccgaccugga cggcgugggc gugaaggccc      660

ugcuggagac cagcgagaag aucaccgccg ugagccugga cgugcuggac aagagacugu      720

ucuggaucca guacaacaga gagggcagca acagccugau cugcagcugc gacuacgacg      780

gcggcagcgu gcacaucagc aagcacccca cccagcacaa ccuguucgcc augagccugu      840

ucggcgacag aaucuucuac agcaccugga agaugaagac caucuggauc gccaacaagc      900

acaccggcaa ggacauggug agaaucaacc ugcacagcag cuucgugccc cugggcgagc      960

ugaagguggu gcacccccug gcccagccca aggccgagga cgacaccugg gagcccgagc     1020

agaagcugug caagcugaga aagggcaacu gcagcagcac cgugugcggc caggaccugc     1080

agagccaccu gugcaugugc gccgagggcu acgcccugag cagagacaga aaguacugcg     1140

aggacgugaa cgagugcgcc uucuggaacc acggcugcac ccugggcugc aagaacaccc     1200

ccggcagcua cuacugcacc ugccccgugg gcuucgugcu gcugcccgac ggcaagagau     1260

gccaccagcu ggugagcugc cccagaaacg ugagcgagug cagccacgac ugcgugcuga     1320

ccagcgaggg cccccugugc uucugccccg agggcagcgu gcuggagaga gacggcaaga     1380

ccugcagcgg cugcagcagc cccgacaacg gcggcugcag ccagcugugc gugccccuga     1440

gccccgugag cugggagugc gacugcuucc ccggcuacga ccugcagcug gacgagaaga     1500

gcugcgccgc cagcggcccc cagcccuucc ugcuguucgc caacagccag gacaucagac     1560

acaugcacuu cgacggcacc gacuacggca cccugcugag ccagcagaug ggcauggugu     1620

acgcccugga ccacgacccc guggagaaca agaucuacuu cgcccacacc gcccugaagu     1680

ggaucgagag agccaacaug gacggcagcc agagagagag acugaucgag gagggcgugg     1740

acgugcccga gggccuggcc guggacugga ucggcagaag auucuacugg accgacagag     1800

gcaagagccu gaucggcaga agcgaccuga acggcaagag aagcaagauc aucaccaagg     1860

agaacaucag ccagcccaga ggcaucgccg ugcaccccau ggccaagaga cuguucugga     1920

ccgacaccgg caucaacccc agaaucgaga gcagcagccu gcagggccug ggcagacugg     1980

ugaucgccag cagcgaccug aucuggccca gcggcaucac caucgacuuc cugaccgaca     2040

agcuguacug gugcgacgcc aagcagagcg ugaucgagau ggccaaccug gacggcagca     2100

agagaagaag acugacccag aacgacgugg gccaccccuu cgccguggcc guguucgagg     2160

acuacgugug guucagcgac ugggccaugc ccagcgugau gagagugaac aagagaaccg     2220

gcaaggacag agugagacug cagggcagca ugcugaagcc cagcagccug gugguggugc     2280

acccccuggc caagcccggc gccgaccccu gccuguacca gaacggcggc ugcgagcaca     2340

ucugcaagaa gagacugggc accgccuggu gcagcugcag agagggcuuc augaaggcca     2400

gcgacggcaa gaccugccug gcccuggacg gccaccagcu gcuggccggc ggcgaggugg     2460

accugaagaa ccaggugacc ccccuggaca uccugagcaa gaccagagug agcgaggaca     2520

acaucaccga gagccagcac augcuggugg ccgagaucau ggugagcgac caggacgacu     2580

gcgcccccgu gggcugcagc auguacgcca gaugcaucag cgagggcgag gacgccaccu     2640

gccagugccu gaagggcuuc gccggcgacg gcaagcugug cagcgacauc gacgagugcg     2700

agaugggcgu gcccgugugc ccccccgcca gcagcaagug caucaacacc gagggcggcu     2760

acgugugcag augcagcgag ggcuaccagg gcgacggcau ccacugccug gacaucgacg     2820

agugccagcu gggcgagcac agcugcggcg agaacgccag cugcaccaac accgagggcg     2880

gcuacaccug caugugcgcc ggcagacuga gcgagcccgg ccugaucugc cccgacagca     2940

cccccccccc ccaccugaga gaggacgacc accacuacag cgugagaaac agcgacagcg     3000

agugcccccu gagccacgac ggcuacugcc ugcacgacgg cgugugcaug uacaucgagg     3060

cccuggacaa guacgccugc aacugcgugg ugggcuacau cggcgagaga ugccaguaca     3120

gagaccugaa guggugggag cugagacacg ccggccacgg ccagcagcag aaggugaucg     3180

ugguggccgu gugcguggug gugcugguga ugcugcugcu gcugagccug uggggcgccc     3240

acuacuacag aacccagaag cugcugagca agaaccccaa gaaccccuac gaggagagca     3300

gcagagacgu gagaagcaga agacccgccg acaccgagga cggcaugagc agcugccccc     3360

agcccugguu cguggugauc aaggagcacc aggaccugaa gaacggcggc cagcccgugg     3420

ccggcgagga cggccaggcc gccgacggca gcaugcagcc caccagcugg agacaggagc     3480

cccagcugug cggcaugggc accgagcagg gcugcuggau ccccgugagc agcgacaagg     3540

gcagcugccc ccaggugaug gagagaagcu uccacaugcc cagcuacggc acccagaccc     3600

uggagggcgg cguggagaag ccccacagcc ugcugagcgc caacccccug uggcagcaga     3660

gagcccugga ccccccccac cagauggagc ugacccagug aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  4218
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt4)

<400>  4218
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggca gaagaaugga gaugcugugc gccggcagag      120

ugcccgcccu gcugcugugc cugggcuucc accugcugca ggccgugcug agcaccaccg      180

ugauccccag cugcaucccc ggcgagagca gcgacaacug caccgcccug gugcagaccg      240

aggacaaccc cagaguggcc caggugagca ucaccaagug cagcagcgac augaacggcu      300

acugccugca cggccagugc aucuaccugg uggacaugag ccagaacuac ugcagaugcg      360

aggugggcua caccggcgug agaugcgagc acuucuuccu gaccgugcac cagccccuga      420

gcaaggagua cguggcccug accgugaucc ugaucauccu guuccugauc accguggugg      480

gcagcaccua cuacuucugc agaugguaca gaaacagaaa gagcaaggag cccaagaagg      540

aguacgagag agugaccagc ggcgaccccg agcugcccca ggugugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  4219
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt4)

<400>  4219
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgagggcg agaucaccac cuucaccgcc cugaccgaga      120

aguucaaccu gccccccggc aacuacaaga agcccaagcu gcuguacugc agcaacggcg      180

gccacuuccu gagaauccug cccgacggca ccguggacgg caccagagac agaagcgacc      240

agcacaucca gcugcagcug agcgccgaga gcgugggcga gguguacauc aagagcaccg      300

agaccggcca guaccuggcc auggacaccg acggccugcu guacggcagc cagaccccca      360

acgaggagug ccuguuccug gagagacugg aggagaacca cuacaacacc uacaucagca      420

agaagcacgc cgagaagaac ugguucgugg gccugaagaa gaacggcagc ugcaagagag      480

gccccagaac ccacuacggc cagaaggcca uccuguuccu gccccugccc gugagcagcg      540

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  4220
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt4)

<400>  4220
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggcgugg gcggcggcga cguggaggac gugaccccca      120

gacccggcgg cugccagauc agcggcagag gcgccagagg cugcaacggc auccccggcg      180

ccgccgccug ggaggccgcc cugcccagaa gaagacccag aagacacccc agcgugaacc      240

ccagaagcag agccgccggc agccccagaa ccagaggcag aagaaccgag gagagaccca      300

gcggcagcag acugggcgac agaggcagag gcagagcccu gcccggcggc agacugggcg      360

gcagaggcag aggcagagcc cccgagagag ugggcggcag aggcagaggc agaggcaccg      420

ccgcccccag agccgccccc gccgccagag gcagcagacc cggccccgcc ggcaccaugg      480

ccgccggcag caucaccacc cugcccgccc ugcccgagga cggcggcagc ggcgccuucc      540

cccccggcca cuucaaggac cccaagagac uguacugcaa gaacggcggc uucuuccuga      600

gaauccaccc cgacggcaga guggacggcg ugagagagaa gagcgacccc cacaucaagc      660

ugcagcugca ggccgaggag agaggcgugg ugagcaucaa gggcgugugc gccaacagau      720

accuggccau gaaggaggac ggcagacugc uggccagcaa gugcgugacc gacgagugcu      780

ucuucuucga gagacuggag agcaacaacu acaacaccua cagaagcaga aaguacacca      840

gcugguacgu ggcccugaag agaaccggcc aguacaagcu gggcagcaag accggccccg      900

gccagaaggc cauccuguuc cugcccauga gcgccaagag cugaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  4221
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt4)

<400>  4221
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uccugaccug gauccugccc acccugcugu      120

acagaagcug cuuccacauc aucugccugg ugggcaccau cagccuggcc ugcaacgaca      180

ugacccccga gcagauggcc accaacguga acugcagcag ccccgagaga cacaccagaa      240

gcuacgacua cauggagggc ggcgacauca gagugagaag acuguucugc agaacccagu      300

gguaccugag aaucgacaag agaggcaagg ugaagggcac ccaggagaug aagaacaacu      360

acaacaucau ggagaucaga accguggccg ugggcaucgu ggccaucaag ggcguggaga      420

gcgaguucua ccuggccaug aacaaggagg gcaagcugua cgccaagaag gagugcaacg      480

aggacugcaa cuucaaggag cugauccugg agaaccacua caacaccuac gccagcgcca      540

aguggaccca caacggcggc gagauguucg uggcccugaa ccagaagggc auccccguga      600

gaggcaagaa gaccaagaag gagcagaaga ccgcccacuu ccugcccaug gccaucaccu      660

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  4222
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt4)

<400>  4222
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugcugc ccagcguggu gcugaagcug uuccuggccg      120

ccgugcugag cgcccuggug accggcgaga gccuggagag acugagaaga ggccuggccg      180

ccggcaccag caaccccgac ccccccaccg ugagcaccga ccagcugcug ccccugggcg      240

gcggcagaga cagaaaggug agagaccugc aggaggccga ccuggaccug cugagaguga      300

cccugagcag caagccccag gcccuggcca cccccaacaa ggaggagcac ggcaagagaa      360

agaagaaggg caagggccug ggcaagaaga gagaccccug ccugagaaag uacaaggacu      420

ucugcaucca cggcgagugc aaguacguga aggagcugag agcccccagc ugcaucugcc      480

accccggcua ccacggcgag agaugccacg gccugagccu gcccguggag aacagacugu      540

acaccuacga ccacaccacc auccuggccg ugguggccgu ggugcugagc agcgugugcc      600

ugcuggugau cgugggccug cugauguuca gauaccacag aagaggcggc uacgacgugg      660

agaacgagga gaaggugaag cugggcauga ccaacagcca cugaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  4223
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt4)

<400>  4223
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcugcc cgcccugcug cugcagcacg      120

ugcugcugca ccugcugcug cugcccaucg ccauccccua cgccgagggc cagagaaaga      180

gaagaaacac cauccacgag uucaagaaga gcgccaagac cacccugauc aagaucgacc      240

ccgcccugaa gaucaagacc aagaagguga acaccgccga ccagugcgcc aacagaugca      300

ccagaaacaa gggccugccc uucaccugca aggccuucgu guucgacaag gccagaaagc      360

agugccugug guuccccuuc aacagcauga gcagcggcgu gaagaaggag uucggccacg      420

aguucgaccu guacgagaac aaggacuaca ucagaaacug caucaucggc aagggcagaa      480

gcuacaaggg caccgugagc aucaccaaga gcggcaucaa gugccagccc uggagcagca      540

ugauccccca cgagcacagc uuccugccca gcagcuacag aggcaaggac cugcaggaga      600

acuacugcag aaaccccaga ggcgaggagg gcggccccug gugcuucacc agcaaccccg      660

aggugagaua cgaggugugc gacauccccc agugcagcga gguggagugc augaccugca      720

acggcgagag cuacagaggc cugauggacc acaccgagag cggcaagauc ugccagagau      780

gggaccacca gaccccccac agacacaagu uccugcccga gagauacccc gacaagggcu      840

ucgacgacaa cuacugcaga aaccccgacg gccagcccag acccuggugc uacacccugg      900

acccccacac cagaugggag uacugcgcca ucaagaccug cgccgacaac accaugaacg      960

acaccgacgu gccccuggag accaccgagu gcauccaggg ccagggcgag ggcuacagag     1020

gcaccgugaa caccaucugg aacggcaucc ccugccagag augggacagc caguaccccc     1080

acgagcacga caugaccccc gagaacuuca agugcaagga ccugagagag aacuacugca     1140

gaaaccccga cggcagcgag agccccuggu gcuucaccac cgaccccaac aucagagugg     1200

gcuacugcag ccagaucccc aacugcgaca ugagccacgg ccaggacugc uacagaggca     1260

acggcaagaa cuacaugggc aaccugagcc agaccagaag cggccugacc ugcagcaugu     1320

gggacaagaa cauggaggac cugcacagac acaucuucug ggagcccgac gccagcaagc     1380

ugaacgagaa cuacugcaga aaccccgacg acgacgccca cggccccugg ugcuacaccg     1440

gcaacccccu gauccccugg gacuacugcc ccaucagcag augcgagggc gacaccaccc     1500

ccaccaucgu gaaccuggac caccccguga ucagcugcgc caagaccaag cagcugagag     1560

uggugaacgg cauccccacc agaaccaaca ucggcuggau ggugagccug agauacagaa     1620

acaagcacau cugcggcggc agccugauca aggagagcug ggugcugacc gccagacagu     1680

gcuuccccag cagagaccug aaggacuacg aggccuggcu gggcauccac gacgugcacg     1740

gcagaggcga cgagaagugc aagcaggugc ugaacgugag ccagcuggug uacggccccg     1800

agggcagcga ccuggugcug augaagcugg ccagacccgc cgugcuggac gacuucguga     1860

gcaccaucga ccugcccaac uacggcugca ccauccccga gaagaccagc ugcagcgugu     1920

acggcugggg cuacaccggc cugaucaacu acgacggccu gcugagagug gcccaccugu     1980

acaucauggg caacgagaag ugcagccagc accacagagg caaggugacc cugaacgaga     2040

gcgagaucug cgccggcgcc gagaagaucg gcagcggccc cugcgagggc gacuacggcg     2100

gcccccuggu gugcgagcag cacaagauga gaauggugcu gggcgugauc gugcccggca     2160

gaggcugcgc cauccccaac agacccggca ucuucgugag aguggccuac uacgccaagu     2220

ggauccacaa gaucauccug accuacaagg ugccccagag cugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  4224
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt4)

<400>  4224
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggccg ccgccaucgg caucgaccug ggcaccaccu      120

acagcugcgu gggcguguuc cagcacggca agguggagau caucgccaac gaccagggca      180

acagaaccac ccccagcuac guggccuuca ccgacaccga gagacugauc ggcgacgccg      240

ccaagaacca gguggcccug aacccccaga acaccguguu cgacgccaag agacugaucg      300

gcagaaaguu cggcgacccc guggugcaga gcgacaugaa gcacuggccc uuccagguga      360

ucaacgacgg cgacaagccc aaggugcagg ugagcuacaa gggcgagacc aaggccuucu      420

accccgagga gaucagcagc auggugcuga ccaagaugaa ggagaucgcc gaggccuacc      480

ugggcuaccc cgugaccaac gccgugauca ccgugcccgc cuacuucaac gacagccaga      540

gacaggccac caaggacgcc ggcgugaucg ccggccugaa cgugcugaga aucaucaacg      600

agcccaccgc cgccgccauc gccuacggcc uggacagaac cggcaagggc gagagaaacg      660

ugcugaucuu cgaccugggc ggcggcaccu ucgacgugag cauccugacc aucgacgacg      720

gcaucuucga ggugaaggcc accgccggcg acacccaccu gggcggcgag gacuucgaca      780

acagacuggu gaaccacuuc guggaggagu ucaagagaaa gcacaagaag gacaucagcc      840

agaacaagag agccgugaga agacugagaa ccgccugcga gagagccaag agaacccuga      900

gcagcagcac ccaggccagc cuggagaucg acagccuguu cgagggcauc gacuucuaca      960

ccagcaucac cagagccaga uucgaggagc ugugcagcga ccuguucaga agcacccugg     1020

agcccgugga gaaggcccug agagacgcca agcuggacaa ggcccagauc cacgaccugg     1080

ugcugguggg cggcagcacc agaaucccca aggugcagaa gcugcugcag gacuucuuca     1140

acggcagaga ccugaacaag agcaucaacc ccgacgaggc cguggccuac ggcgccgccg     1200

ugcaggccgc cauccugaug ggcgacaaga gcgagaacgu gcaggaccug cugcugcugg     1260

acguggcccc ccugagccug ggccuggaga ccgccggcgg cgugaugacc gcccugauca     1320

agagaaacag caccaucccc accaagcaga cccagaucuu caccaccuac agcgacaacc     1380

agcccggcgu gcugauccag guguacgagg gcgagagagc caugaccaag gacaacaacc     1440

ugcugggcag auucgagcug agcggcaucc cccccgcccc cagaggcgug ccccagaucg     1500

aggugaccuu cgacaucgac gccaacggca uccugaacgu gaccgccacc gacaagagca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg cagacugagc aaggaggaga     1620

ucgagagaau ggugcaggag gccgagaagu acaaggccga ggacgaggug cagagagaga     1680

gagugagcgc caagaacgcc cuggagagcu acgccuucaa caugaagagc gccguggagg     1740

acgagggccu gaagggcaag aucagcgagg ccgacaagaa gaaggugcug gacaagugcc     1800

aggaggugau cagcuggcug gacgccaaca cccuggccga gaaggacgag uucgagcaca     1860

agagaaagga gcuggagcag gugugcaacc ccaucaucag cggccuguac cagggcgccg     1920

gcggccccgg ccccggcggc uucggcgccc agggccccaa gggcggcagc ggcagcggcc     1980

ccaccaucga ggagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4225
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt4)

<400>  4225
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggccg ccgccaucgg caucgaccug ggcaccaccu      120

acagcugcgu gggcguguuc cagcacggca agguggagau caucgccaac gaccagggca      180

acagaaccac ccccagcuac guggccuuca ccgacaccga gagacugauc ggcgacgccg      240

ccaagaacca gguggcccug aacccccaga acaccguguu cgacgccaag agacugaucg      300

gcagaaaguu cggcgacccc guggugcaga gcgacaugaa gcacuggccc uuccagguga      360

ucaacgacgg cgacaagccc aaggugcagg ugagcuacaa gggcgagacc aaggccuucu      420

accccgagga gaucagcagc auggugcuga ccaagaugaa ggagaucgcc gaggccuacc      480

ugggcuaccc cgugaccaac gccgugauca ccgugcccgc cuacuucaac gacagccaga      540

gacaggccac caaggacgcc ggcgugaucg ccggccugaa cgugcugaga aucaucaacg      600

agcccaccgc cgccgccauc gccuacggcc uggacagaac cggcaagggc gagagaaacg      660

ugcugaucuu cgaccugggc ggcggcaccu ucgacgugag cauccugacc aucgacgacg      720

gcaucuucga ggugaaggcc accgccggcg acacccaccu gggcggcgag gacuucgaca      780

acagacuggu gaaccacuuc guggaggagu ucaagagaaa gcacaagaag gacaucagcc      840

agaacaagag agccgugaga agacugagaa ccgccugcga gagagccaag agaacccuga      900

gcagcagcac ccaggccagc cuggagaucg acagccuguu cgagggcauc gacuucuaca      960

ccagcaucac cagagccaga uucgaggagc ugugcagcga ccuguucaga agcacccugg     1020

agcccgugga gaaggcccug agagacgcca agcuggacaa ggcccagauc cacgaccugg     1080

ugcugguggg cggcagcacc agaaucccca aggugcagaa gcugcugcag gacuucuuca     1140

acggcagaga ccugaacaag agcaucaacc ccgacgaggc cguggccuac ggcgccgccg     1200

ugcaggccgc cauccugaug ggcgacaaga gcgagaacgu gcaggaccug cugcugcugg     1260

acguggcccc ccugagccug ggccuggaga ccgccggcgg cgugaugacc gcccugauca     1320

agagaaacag caccaucccc accaagcaga cccagaucuu caccaccuac agcgacaacc     1380

agcccggcgu gcugauccag guguacgagg gcgagagagc caugaccaag gacaacaacc     1440

ugcugggcag auucgagcug agcggcaucc cccccgcccc cagaggcgug ccccagaucg     1500

aggugaccuu cgacaucgac gccaacggca uccugaacgu gaccgccacc gacaagagca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg cagacugagc aaggaggaga     1620

ucgagagaau ggugcaggag gccgagaagu acaaggccga ggacgaggug cagagagaga     1680

gagugagcgc caagaacgcc cuggagagcu acgccuucaa caugaagagc gccguggagg     1740

acgagggccu gaagggcaag aucagcgagg ccgacaagaa gaaggugcug gacaagugcc     1800

aggaggugau cagcuggcug gacgccaaca cccuggccga gaaggacgag uucgagcaca     1860

agagaaagga gcuggagcag gugugcaacc ccaucaucag cggccuguac cagggcgccg     1920

gcggccccgg ccccggcggc uucggcgccc agggccccaa gggcggcagc ggcagcggcc     1980

ccaccaucga ggagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4226
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt4)

<400>  4226
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaccgcca agggcaucgc caucggcauc gaccugggca      120

ccaccuacag cugcgugggc guguuccagc acggcaaggu ggagaucauc gccaacgacc      180

agggcaacag aaccaccccc agcuacgugg ccuucaccga caccgagaga cugaucggcg      240

acgccgccaa gaaccaggug gccaugaacc cccagaacac cguguucgac gccaagagac      300

ugaucggcag aaaguucaac gaccccgugg ugcaggccga caugaagcug uggcccuucc      360

aggugaucaa cgagggcggc aagcccaagg ugcuggugag cuacaagggc gagaacaagg      420

ccuucuaccc cgaggagauc agcagcaugg ugcugaccaa gcugaaggag accgccgagg      480

ccuuccuggg ccaccccgug accaacgccg ugaucaccgu gcccgccuac uucaacgaca      540

gccagagaca ggccaccaag gacgccggcg ugaucgccgg ccugaacgug cugagaauca      600

ucaacgagcc caccgccgcc gccaucgccu acggccugga caagggcggc cagggcgaga      660

gacacgugcu gaucuucgac cugggcggcg gcaccuucga cgugagcauc cugaccaucg      720

acgacggcau cuucgaggug aaggccaccg ccggcgacac ccaccugggc ggcgaggacu      780

ucgacaacag acuggugagc cacuucgugg aggaguucaa gagaaagcac aagaaggaca      840

ucagccagaa caagagagcc gugagaagac ugagaaccgc cugcgagaga gccaagagaa      900

cccugagcag cagcacccag gccaaccugg agaucgacag ccuguacgag ggcaucgacu      960

ucuacaccag caucaccaga gccagauucg aggagcugug cgccgaccug uucagaggca     1020

cccuggagcc cguggagaag gcccugagag acgccaagau ggacaaggcc aagauccacg     1080

acaucgugcu ggugggcggc agcaccagaa uccccaaggu gcagagacug cugcaggacu     1140

acuucaacgg cagagaccug aacaagagca ucaaccccga cgaggccgug gccuacggcg     1200

ccgccgugca ggccgccauc cugaugggcg acaagagcga gaaggugcag gaccugcugc     1260

ugcuggacgu ggccccccug agccugggcc uggagaccgc cggcggcgug augaccgccc     1320

ugaucaagag aaacagcacc auccccacca agcagaccca gaucuucacc accuacagcg     1380

acaaccagcc cggcgugcug auccaggugu acgagggcga gagagccaug accaaggaca     1440

acaaccugcu gggcagauuc gaccugaccg gcaucccccc cgcccccaga ggcgugcccc     1500

agaucgaggu gaccuucgac aucgacgcca acggcauccu gaacgugacc gccaccgaca     1560

agagcaccgg caaggugaac aagaucacca ucaccaacga caagggcaga cugagcaagg     1620

aggagaucga gagaauggug cuggacgccg agaaguacaa ggccgaggac gaggugcaga     1680

gagagaagau cgccgccaag aacgcccugg agagcuacgc cuucaacaug aagagcgugg     1740

ugagcgacga gggccugaag ggcaagauca gcgagagcga caagaacaag auccuggaca     1800

agugcaacga gcugcugagc uggcuggagg ugaaccagcu ggccgagaag gacgaguucg     1860

accacaagag aaaggagcug gagcagaugu gcaaccccau caucaccaag cuguaccagg     1920

gcggcugcac cggccccgcc ugcggcaccg gcuacgugcc cggcagaccc gccaccggcc     1980

ccaccaucga ggagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4227
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt4)

<400>  4227
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgccagag gccccgccau cggcaucgac cugggcacca      120

ccuacagcug cgugggcgug uuccagcacg gcaaggugga gaucaucgcc aacgaccagg      180

gcaacagaac cacccccagc uacguggccu ucaccgacac cgagagacug aucggcgacg      240

ccgccaagaa ccagguggcc augaacccca ccaacaccau cuucgacgcc aagagacuga      300

ucggcagaaa guucgaggac gccaccgugc agagcgacau gaagcacugg cccuucagag      360

uggugagcga gggcggcaag cccaaggugc agguggagua caagggcgag accaagaccu      420

ucuuccccga ggagaucagc agcauggugc ugaccaagau gaaggagauc gccgaggccu      480

accugggcgg caaggugcac agcgccguga ucaccgugcc cgccuacuuc aacgacagcc      540

agagacaggc caccaaggac gccggcacca ucaccggccu gaacgugcug agaaucauca      600

acgagcccac cgccgccgcc aucgccuacg gccuggacaa gaagggcugc gccggcggcg      660

agaagaacgu gcugaucuuc gaccugggcg gcggcaccuu cgacgugagc auccugacca      720

ucgaggacgg caucuucgag gugaagagca ccgccggcga cacccaccug ggcggcgagg      780

acuucgacaa cagaauggug agccaccugg ccgaggaguu caagagaaag cacaagaagg      840

acaucggccc caacaagaga gccgugagaa gacugagaac cgccugcgag agagccaaga      900

gaacccugag cagcagcacc caggccagca ucgagaucga cagccuguac gagggcgugg      960

acuucuacac cagcaucacc agagccagau ucgaggagcu gaacgccgac cuguucagag     1020

gcacccugga gcccguggag aaggcccuga gagacgccaa gcuggacaag ggccagaucc     1080

aggagaucgu gcuggugggc ggcagcacca gaauccccaa gauccagaag cugcugcagg     1140

acuucuucaa cggcaaggag cugaacaaga gcaucaaccc cgacgaggcc guggccuacg     1200

gcgccgccgu gcaggccgcc auccugaucg gcgacaagag cgagaacgug caggaccugc     1260

ugcugcugga cgugaccccc cugagccugg gcaucgagac cgccggcggc gugaugaccc     1320

cccugaucaa gagaaacacc accaucccca ccaagcagac ccagaccuuc accaccuaca     1380

gcgacaacca gagcagcgug cuggugcagg uguacgaggg cgagagagcc augaccaagg     1440

acaacaaccu gcugggcaag uucgaccuga ccggcauccc ccccgccccc agaggcgugc     1500

cccagaucga ggugaccuuc gacaucgacg ccaacggcau ccugaacgug accgccgccg     1560

acaagagcac cggcaaggag aacaagauca ccaucaccaa cgacaagggc agacugagca     1620

aggacgacau cgacagaaug gugcaggagg ccgagagaua caagagcgag gacgaggcca     1680

acagagacag aguggccgcc aagaacgccc uggagagcua caccuacaac aucaagcaga     1740

ccguggagga cgagaagcug agaggcaaga ucagcgagca ggacaagaac aagauccugg     1800

acaagugcca ggaggugauc aacuggcugg acagaaacca gauggccgag aaggacgagu     1860

acgagcacaa gcagaaggag cuggagagag ugugcaaccc caucaucagc aagcuguacc     1920

agggcggccc cggcggcggc agcggcggcg gcggcagcgg cgccagcggc ggccccacca     1980

ucgaggaggu ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  4228
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt4)

<400>  4228
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggugg gcaucgaccu gggcuuccag agcugcuacg      120

uggccguggc cagagccggc ggcaucgaga ccaucgccaa cgaguacagc gacagaugca      180

cccccgccug caucagcuuc ggccccaaga acagaagcau cggcgccgcc gccaagagcc      240

aggugaucag caacgccaag aacaccgugc agggcuucaa gagauuccac ggcagagccu      300

ucagcgaccc cuucguggag gccgagaaga gcaaccuggc cuacgacauc gugcagcugc      360

ccaccggccu gaccggcauc aaggugaccu acauggagga ggagagaaac uucaccaccg      420

agcaggugac cgccaugcug cugagcaagc ugaaggagac cgccgagagc gugcugaaga      480

agcccguggu ggacugcgug gugagcgugc ccugcuucua caccgacgcc gagagaagaa      540

gcgugaugga cgccacccag aucgccggcc ugaacugccu gagacugaug aacgagacca      600

ccgccguggc ccuggccuac ggcaucuaca agcaggaccu gcccgcccug gaggagaagc      660

ccagaaacgu gguguucgug gacaugggcc acagcgccua ccaggugagc gugugcgccu      720

ucaacagagg caagcugaag gugcuggcca ccgccuucga caccacccug ggcggcagaa      780

aguucgacga ggugcuggug aaccacuucu gcgaggaguu cggcaagaag uacaagcugg      840

acaucaagag caagaucaga gcccugcuga gacugagcca ggagugcgag aagcugaaga      900

agcugaugag cgccaacgcc agcgaccugc cccugagcau cgagugcuuc augaacgacg      960

uggacgugag cggcaccaug aacagaggca aguuccugga gaugugcaac gaccugcugg     1020

ccagagugga gcccccccug agaagcgugc uggagcagac caagcugaag aaggaggaca     1080

ucuacgccgu ggagaucgug ggcggcgcca ccagaauccc cgccgugaag gagaagauca     1140

gcaaguucuu cggcaaggag cugagcacca cccugaacgc cgacgaggcc gugaccagag     1200

gcugcgcccu gcagugcgcc auccugagcc ccgccuucaa ggugagagag uucagcauca     1260

ccgacguggu gcccuacccc aucagccuga gauggaacag ccccgccgag gagggcagca     1320

gcgacugcga gguguucagc aagaaccacg ccgcccccuu cagcaaggug cugaccuucu     1380

acagaaagga gcccuucacc cuggaggccu acuacagcag cccccaggac cugcccuacc     1440

ccgaccccgc caucgcccag uucagcgugc agaaggugac cccccagagc gacggcagca     1500

gcagcaaggu gaaggugaag gugagaguga acgugcacgg caucuucagc gugagcagcg     1560

ccagccuggu ggaggugcac aagagcgagg agaacgagga gcccauggag accgaccaga     1620

acgccaagga ggaggagaag augcaggugg accaggagga gccccacgug gaggagcagc     1680

agcagcagac ccccgccgag aacaaggccg agagcgagga gauggagacc agccaggccg     1740

gcagcaagga caagaagaug gaccagcccc cccaggccaa gaaggccaag gugaagacca     1800

gcaccgugga ccugcccauc gagaaccagc ugcuguggca gaucgacaga gagaugcuga     1860

accuguacau cgagaacgag ggcaagauga ucaugcagga caagcuggag aaggagagaa     1920

acgacgccaa gaacgccgug gaggaguacg uguacgagau gagagacaag cugagcggcg     1980

aguacgagaa guucgugagc gaggacgaca gaaacagcuu cacccugaag cuggaggaca     2040

ccgagaacug gcuguacgag gacggcgagg accagcccaa gcagguguac guggacaagc     2100

uggccgagcu gaagaaccug ggccagccca ucaagaucag auuccaggag agcgaggaga     2160

gacccaagcu guucgaggag cugggcaagc agauccagca guacaugaag aucaucagca     2220

gcuucaagaa caaggaggac caguacgacc accuggacgc cgccgacaug accaaggugg     2280

agaagagcac caacgaggcc auggagugga ugaacaacaa gcugaaccug cagaacaagc     2340

agagccugac cauggacccc guggugaaga gcaaggagau cgaggccaag aucaaggagc     2400

ugaccagcac cugcagcccc aucaucagca agcccaagcc caagguggag ccccccaagg     2460

aggagcagaa gaacgccgag cagaacggcc ccguggacgg ccagggcgac aaccccggcc     2520

cccaggccgc cgagcagggc accgacaccg ccgugcccag cgacagcgac aagaagcugc     2580

ccgagaugga caucgacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  4229
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt4)

<400>  4229
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggugg gcaucgaccu gggcuuccug aacugcuaca      120

ucgccguggc cagaagcggc ggcaucgaga ccaucgccaa cgaguacagc gacagaugca      180

cccccgccug caucagccug ggcagcagaa ccagagccau cggcaacgcc gccaagagcc      240

agaucgugac caacgugaga aacaccaucc acggcuucaa gaagcugcac ggcagaagcu      300

ucgacgaccc caucgugcag accgagagaa ucagacugcc cuacgagcug cagaagaugc      360

ccaacggcag cgccggcgug aaggugagau accuggagga ggagagaccc uucgccaucg      420

agcaggugac cggcaugcug cuggccaagc ugaaggagac cagcgagaac gcccugaaga      480

agcccguggc cgacugcgug aucagcaucc ccagcuucuu caccgacgcc gagagaagaa      540

gcgugauggc cgccgcccag guggccggcc ugaacugccu gagacugaug aacgagacca      600

ccgccguggc ccuggccuac ggcaucuaca agcaggaccu gcccccccug gacgagaagc      660

ccagaaacgu gguguucauc gacaugggcc acagcgccua ccaggugcug gugugcgccu      720

ucaacaaggg caagcugaag gugcuggcca ccaccuucga ccccuaccug ggcggcagaa      780

acuucgacga ggcccuggug gacuacuucu gcgacgaguu caagaccaag uacaagauca      840

acgugaagga gaacagcaga gcccugcuga gacuguacca ggagugcgag aagcugaaga      900

agcugaugag cgccaacgcc agcgaccugc cccugaacau cgagugcuuc augaacgacc      960

uggacgugag cagcaagaug aacagagccc aguucgagca gcugugcgcc agccugcugg     1020

ccagagugga gcccccccug aaggccguga uggagcaggc caaccugcag agagaggaca     1080

ucagcagcau cgagaucgug ggcggcgcca ccagaauccc cgccgugaag gagcagauca     1140

ccaaguucuu ccugaaggac aucagcacca cccugaacgc cgacgaggcc guggccagag     1200

gcugcgcccu gcagugcgcc auccugagcc ccgccuucaa ggugagagag uucagcauca     1260

ccgaccuggu gcccuacagc aucacccuga gauggaagac cagcuucgag gacggcagcg     1320

gcgagugcga gguguucugc aagaaccacc ccgcccccuu cagcaaggug aucaccuucc     1380

acaagaagga gcccuucgag cuggaggccu ucuacaccaa ccugcacgag gugcccuacc     1440

ccgacgccag aaucggcagc uucaccaucc agaacguguu cccccagagc gacggcgaca     1500

gcagcaaggu gaaggugaag gugagaguga acauccacgg caucuucagc guggccagcg     1560

ccagcgugau cgagaagcag aaccuggagg gcgaccacag cgacgccccc auggagaccg     1620

agaccagcuu caagaacgag aacaaggaca acauggacaa gaugcaggug gaccaggagg     1680

agggccacca gaagugccac gccgagcaca cccccgagga ggagaucgac cacaccggcg     1740

ccaagaccaa gagcgccgug agcgacaagc aggacagacu gaaccagacc cugaagaagg     1800

gcaaggugaa gagcaucgac cugcccaucc agagcagccu gugcagacag cugggccagg     1860

accugcugaa cagcuacauc gagaacgagg gcaagaugau caugcaggac aagcuggaga     1920

aggagagaaa cgacgccaag aacgccgugg aggaguacgu guacgacuuc agagacagac     1980

ugggcaccgu guacgagaag uucaucaccc ccgaggaccu gagcaagcug agcgccgugc     2040

uggaggacac cgagaacugg cuguacgagg acggcgagga ccagcccaag cagguguacg     2100

uggacaagcu gcaggagcug aagaaguacg gccagcccau ccagaugaag uacauggagc     2160

acgaggagag acccaaggcc cugaacgacc ugggcaagaa gauccagcug gugaugaagg     2220

ugaucgaggc cuacagaaac aaggacgaga gauacgacca ccuggacccc accgagaugg     2280

agaaggugga gaagugcauc agcgacgcca ugagcuggcu gaacagcaag augaacgccc     2340

agaacaagcu gagccugacc caggaccccg uggugaaggu gagcgagauc guggccaaga     2400

gcaaggagcu ggacaacuuc ugcaacccca ucaucuacaa gcccaagccc aaggccgagg     2460

ugcccgagga caagcccaag gccaacagcg agcacaacgg ccccauggac ggccagagcg     2520

gcaccgagac caagagcgac agcaccaagg acagcagcca gcacaccaag agcagcggcg     2580

agauggaggu ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  4230
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt4)

<400>  4230
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugagcc ugguggccgc caugcugcug cugcugagcg      120

ccgccagagc cgaggaggag gacaagaagg aggacguggg caccguggug ggcaucgacc      180

ugggcaccac cuacagcugc gugggcgugu ucaagaacgg cagaguggag aucaucgcca      240

acgaccaggg caacagaauc acccccagcu acguggccuu cacccccgag ggcgagagac      300

ugaucggcga cgccgccaag aaccagcuga ccagcaaccc cgagaacacc guguucgacg      360

ccaagagacu gaucggcaga accuggaacg accccagcgu gcagcaggac aucaaguucc      420

ugcccuucaa ggugguggag aagaagacca agcccuacau ccagguggac aucggcggcg      480

gccagaccaa gaccuucgcc cccgaggaga ucagcgccau ggugcugacc aagaugaagg      540

agaccgccga ggccuaccug ggcaagaagg ugacccacgc cguggugacc gugcccgccu      600

acuucaacga cgcccagaga caggccacca aggacgccgg caccaucgcc ggccugaacg      660

ugaugagaau caucaacgag cccaccgccg ccgccaucgc cuacggccug gacaagagag      720

agggcgagaa gaacauccug guguucgacc ugggcggcgg caccuucgac gugagccugc      780

ugaccaucga caacggcgug uucgaggugg uggccaccaa cggcgacacc caccugggcg      840

gcgaggacuu cgaccagaga gugauggagc acuucaucaa gcuguacaag aagaagaccg      900

gcaaggacgu gagaaaggac aacagagccg ugcagaagcu gagaagagag guggagaagg      960

ccaagagagc ccugagcagc cagcaccagg ccagaaucga gaucgagagc uucuacgagg     1020

gcgaggacuu cagcgagacc cugaccagag ccaaguucga ggagcugaac auggaccugu     1080

ucagaagcac caugaagccc gugcagaagg ugcuggagga cagcgaccug aagaagagcg     1140

acaucgacga gaucgugcug gugggcggca gcaccagaau ccccaagauc cagcagcugg     1200

ugaaggaguu cuucaacggc aaggagccca gcagaggcau caaccccgac gaggccgugg     1260

ccuacggcgc cgccgugcag gccggcgugc ugagcggcga ccaggacacc ggcgaccugg     1320

ugcugcugga cgugugcccc cugacccugg gcaucgagac cgugggcggc gugaugacca     1380

agcugauccc cagaaacacc guggugccca ccaagaagag ccagaucuuc agcaccgcca     1440

gcgacaacca gcccaccgug accaucaagg uguacgaggg cgagagaccc cugaccaagg     1500

acaaccaccu gcugggcacc uucgaccuga ccggcauccc ccccgccccc agaggcgugc     1560

cccagaucga ggugaccuuc gagaucgacg ugaacggcau ccugagagug accgccgagg     1620

acaagggcac cggcaacaag aacaagauca ccaucaccaa cgaccagaac agacugaccc     1680

ccgaggagau cgagagaaug gugaacgacg ccgagaaguu cgccgaggag gacaagaagc     1740

ugaaggagag aaucgacacc agaaacgagc uggagagcua cgccuacagc cugaagaacc     1800

agaucggcga caaggagaag cugggcggca agcugagcag cgaggacaag gagaccaugg     1860

agaaggccgu ggaggagaag aucgaguggc uggagagcca ccaggacgcc gacaucgagg     1920

acuucaaggc caagaagaag gagcuggagg agaucgugca gcccaucauc agcaagcugu     1980

acggcagcgc cggccccccc cccaccggcg aggaggacac cgccgagaag gacgagcugu     2040

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  4231
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt4)

<400>  4231
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gagagcuggc cgugggcauc gaccugggca      120

ccaccuacag cugcgugggc guguuccagc agggcagagu ggagauccug gccaacgacc      180

agggcaacag aaccaccccc agcuacgugg ccuucaccga caccgagaga cuggugggcg      240

acgccgccaa gagccaggcc gcccugaacc cccacaacac cguguucgac gccaagagac      300

ugaucggcag aaaguucgcc gacaccaccg ugcagagcga caugaagcac uggcccuuca      360

gaguggugag cgagggcggc aagcccaagg ugagagugug cuacagaggc gaggacaaga      420

ccuucuaccc cgaggagauc agcagcaugg ugcugagcaa gaugaaggag accgccgagg      480

ccuaccuggg ccagcccgug aagcacgccg ugaucaccgu gcccgccuac uucaacgaca      540

gccagagaca ggccaccaag gacgccggcg ccaucgccgg ccugaacgug cugagaauca      600

ucaacgagcc caccgccgcc gccaucgccu acggccugga cagaagaggc gccggcgaga      660

gaaacgugcu gaucuucgac cugggcggcg gcaccuucga cgugagcgug cugagcaucg      720

acgccggcgu guucgaggug aaggccaccg ccggcgacac ccaccugggc ggcgaggacu      780

ucgacaacag acuggugaac cacuucaugg aggaguucag aagaaagcac ggcaaggacc      840

ugagcggcaa caagagagcc cugagaagac ugagaaccgc cugcgagaga gccaagagaa      900

cccugagcag cagcacccag gccacccugg agaucgacag ccuguucgag ggcguggacu      960

ucuacaccag caucaccaga gccagauucg aggagcugug cagcgaccug uucagaagca     1020

cccuggagcc cguggagaag gcccugagag acgccaagcu ggacaaggcc cagauccacg     1080

acguggugcu ggugggcggc agcaccagaa uccccaaggu gcagaagcug cugcaggacu     1140

ucuucaacgg caaggagcug aacaagagca ucaaccccga cgaggccgug gccuacggcg     1200

ccgccgugca ggccgccgug cugaugggcg acaagugcga gaaggugcag gaccugcugc     1260

ugcuggacgu ggccccccug agccugggcc uggagaccgc cggcggcgug augaccaccc     1320

ugauccagag aaacgccacc auccccacca agcagaccca gaccuucacc accuacagcg     1380

acaaccagcc cggcguguuc auccaggugu acgagggcga gagagccaug accaaggaca     1440

acaaccugcu gggcagauuc gagcugagcg gcaucccccc cgcccccaga ggcgugcccc     1500

agaucgaggu gaccuucgac aucgacgcca acggcauccu gagcgugacc gccaccgaca     1560

gaagcaccgg caaggccaac aagaucacca ucaccaacga caagggcaga cugagcaagg     1620

aggaggugga gagaauggug cacgaggccg agcaguacaa ggccgaggac gaggcccaga     1680

gagacagagu ggccgccaag aacagccugg aggcccacgu guuccacgug aagggcagcc     1740

ugcaggagga gagccugaga gacaagaucc ccgaggagga cagaagaaag augcaggaca     1800

agugcagaga ggugcuggcc uggcuggagc acaaccagcu ggccgagaag gaggaguacg     1860

agcaccagaa gagagagcug gagcagaucu gcagacccau cuucagcaga cuguacggcg     1920

gccccggcgu gcccggcggc agcagcugcg gcacccaggc cagacagggc gaccccagca     1980

ccggccccau caucgaggag guggacugag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  4232
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt4)

<400>  4232
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gagagcuggc cgugggcauc gaccugggca      120

ccaccuacag cugcgugggc guguuccagc agggcagagu ggagauccug gccaacgacc      180

agggcaacag aaccaccccc agcuacgugg ccuucaccga caccgagaga cuggugggcg      240

acgccgccaa gagccaggcc gcccugaacc cccacaacac cguguucgac gccaagagac      300

ugaucggcag aaaguucgcc gacaccaccg ugcagagcga caugaagcac uggcccuucc      360

agguggugag cgagggcggc aagcccaagg ugagagugug cuacagaggc gaggacaaga      420

ccuucuaccc cgaggagauc agcagcaugg ugcugagcaa gaugaaggag accgccgagg      480

ccuaccuggg ccagcccgug aagcacgccg ugaucaccgu gcccaccuac uucagcaaca      540

gccagagaca ggccaccaag gacgccggcg ccaucgccgg ccugaaggug cugcccauca      600

ucaacgaggc caccgccgcc gccaucgccu acggccugga cagaagaggc gccggcaaga      660

gaaacgugcu gaucuucgac cugggcggcg gcaccuucga cgugagcgug cugagcaucg      720

acgccggcgu guucgaggug aaggccaccg ccggcgacac ccaccugggc ggcgaggacu      780

ucgacaacag acuggugaac cacuucaugg aggaguucag aagaaagcac ggcaaggacc      840

ugagcggcaa caagagagcc cugagaagac ugagaaccgc cugcgagaga gccaagagaa      900

cccccagcag cagcacccag gccacccugg agaucgacag ccuguucgag ggcguggacu      960

ucuacaagag caucaccaga gccagauucg aggagcugug cagcgaccug uucagaagca     1020

cccuggagcc cguggagaag gcccugagag acgccaagcu ggacaaggcc cagauccacg     1080

acuucgugcu gggcggcggc cugcacagcc acccccaggg cgccgaggug gccgccggcc     1140

ugcugcagag acagggcgcc gagcaggagc accagcccug aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  4233
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt4)

<400>  4233
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaagggcc ccgccguggg caucgaccug ggcaccaccu      120

acagcugcgu gggcguguuc cagcacggca agguggagau caucgccaac gaccagggca      180

acagaaccac ccccagcuac guggccuuca ccgacaccga gagacugauc ggcgacgccg      240

ccaagaacca gguggccaug aaccccacca acaccguguu cgacgccaag agacugaucg      300

gcagaagauu cgacgacgcc guggugcaga gcgacaugaa gcacuggccc uucauggugg      360

ugaacgacgc cggcagaccc aaggugcagg uggaguacaa gggcgagacc aagagcuucu      420

accccgagga ggugagcagc auggugcuga ccaagaugaa ggagaucgcc gaggccuacc      480

ugggcaagac cgugaccaac gccgugguga ccgugcccgc cuacuucaac gacagccaga      540

gacaggccac caaggacgcc ggcaccaucg ccggccugaa cgugcugaga aucaucaacg      600

agcccaccgc cgccgccauc gccuacggcc uggacaagaa ggugggcgcc gagagaaacg      660

ugcugaucuu cgaccugggc ggcggcaccu ucgacgugag cauccugacc aucgaggacg      720

gcaucuucga ggugaagagc accgccggcg acacccaccu gggcggcgag gacuucgaca      780

acagaauggu gaaccacuuc aucgccgagu ucaagagaaa gcacaagaag gacaucagcg      840

agaacaagag agccgugaga agacugagaa ccgccugcga gagagccaag agaacccuga      900

gcagcagcac ccaggccagc aucgagaucg acagccugua cgagggcauc gacuucuaca      960

ccagcaucac cagagccaga uucgaggagc ugaacgccga ccuguucaga ggcacccugg     1020

accccgugga gaaggcccug agagacgcca agcuggacaa gagccagauc cacgacaucg     1080

ugcugguggg cggcagcacc agaaucccca agauccagaa gcugcugcag gacuucuuca     1140

acggcaagga gcugaacaag agcaucaacc ccgacgaggc cguggccuac ggcgccgccg     1200

ugcaggccgc cauccugagc ggcgacaaga gcgagaacgu gcaggaccug cugcugcugg     1260

acgugacccc ccugagccug ggcaucgaga ccgccggcgg cgugaugacc gugcugauca     1320

agagaaacac caccaucccc accaagcaga cccagaccuu caccaccuac agcgacaacc     1380

agcccggcgu gcugauccag guguacgagg gcgagagagc caugaccaag gacaacaacc     1440

ugcugggcaa guucgagcug accggcaucc cccccgcccc cagaggcgug ccccagaucg     1500

aggugaccuu cgacaucgac gccaacggca uccugaacgu gagcgccgug gacaagagca     1560

ccggcaagga gaacaagauc accaucacca acgacaaggg cagacugagc aaggaggaca     1620

ucgagagaau ggugcaggag gccgagaagu acaaggccga ggacgagaag cagagagaca     1680

aggugagcag caagaacagc cuggagagcu acgccuucaa caugaaggcc accguggagg     1740

acgagaagcu gcagggcaag aucaacgacg aggacaagca gaagauccug gacaagugca     1800

acgagaucau caacuggcug gacaagaacc agaccgccga gaaggaggag uucgagcacc     1860

agcagaagga gcuggagaag gugugcaacc ccaucaucac caagcuguac cagagcgccg     1920

gcggcaugcc cggcggcaug cccggcggcu uccccggcgg cggcgccccc cccagcggcg     1980

gcgccagcag cggccccacc aucgaggagg uggacugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  4234
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt4)

<400>  4234
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucagcgcca gcagagccgc cgccgccaga cuggugggcg      120

ccgccgccag cagaggcccc accgccgcca gacaccagga cagcuggaac ggccugagcc      180

acgaggccuu cagacuggug agcagaagag acuacgccag cgaggccauc aagggcgccg      240

uggugggcau cgaccugggc accaccaaca gcugcguggc cgugauggag ggcaagcagg      300

ccaaggugcu ggagaacgcc gagggcgcca gaaccacccc cagcguggug gccuucaccg      360

ccgacggcga gagacuggug ggcaugcccg ccaagagaca ggccgugacc aaccccaaca      420

acaccuucua cgccaccaag agacugaucg gcagaagaua cgacgacccc gaggugcaga      480

aggacaucaa gaacgugccc uucaagaucg ugagagccag caacggcgac gccugggugg      540

aggcccacgg caagcuguac agccccagcc agaucggcgc cuucgugcug augaagauga      600

aggagaccgc cgagaacuac cugggccaca ccgccaagaa cgccgugauc accgugcccg      660

ccuacuucaa cgacagccag agacaggcca ccaaggacgc cggccagauc agcggccuga      720

acgugcugag agugaucaac gagcccaccg ccgccgcccu ggccuacggc cuggacaaga      780

gcgaggacaa ggugaucgcc guguacgacc ugggcggcgg caccuucgac aucagcaucc      840

uggagaucca gaagggcgug uucgagguga agagcaccaa cggcgacacc uuccugggcg      900

gcgaggacuu cgaccaggcc cugcugagac acaucgugaa ggaguucaag agagagaccg      960

gcguggaccu gaccaaggac aacauggccc ugcagagagu gagagaggcc gccgagaagg     1020

ccaagugcga gcugagcagc agcgugcaga ccgacaucaa ccugcccuac cugaccaugg     1080

acagcagcgg ccccaagcac cugaacauga agcugaccag agcccaguuc gagggcaucg     1140

ugaccgaccu gaucagaaga accaucgccc ccugccagaa ggccaugcag gacgccgagg     1200

ugagcaagag cgacaucggc gaggugaucc uggugggcgg caugaccaga augcccaagg     1260

ugcagcagac cgugcaggac cuguucggca gagcccccag caaggccgug aaccccgacg     1320

aggccguggc caucggcgcc gccauccagg gcggcgugcu ggccggcgac gugaccgacg     1380

ugcugcugcu ggacgugacc ccccugagcc ugggcaucga gacccugggc ggcguguuca     1440

ccaagcugau caacagaaac accaccaucc ccaccaagaa gagccaggug uucagcaccg     1500

ccgccgacgg ccagacccag guggagauca aggugugcca gggcgagaga gagauggccg     1560

gcgacaacaa gcugcugggc caguucaccc ugaucggcau cccccccgcc cccagaggcg     1620

ugccccagau cgaggugacc uucgacaucg acgccaacgg caucgugcac gugagcgcca     1680

aggacaaggg caccggcaga gagcagcaga ucgugaucca gagcagcggc ggccugagca     1740

aggacgacau cgagaacaug gugaagaacg ccgagaagua cgccgaggag gacagaagaa     1800

agaaggagag aguggaggcc gugaacaugg ccgagggcau cauccacgac accgagacca     1860

agauggagga guucaaggac cagcugcccg ccgacgagug caacaagcug aaggaggaga     1920

ucagcaagau gagagagcug cuggccagaa aggacagcga gaccggcgag aacaucagac     1980

aggccgccag cagccugcag caggccagcc ugaagcuguu cgagauggcc uacaagaaga     2040

uggccagcga gagagagggc agcggcagca gcggcaccgg cgagcagaag gaggaccaga     2100

aggaggagaa gcagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  4235
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt4)

<400>  4235
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg aggccggcgg cagcgacggc cccagagaga      120

ccgcccccac cagcgccuac agcagccccg ccagaagccu gggcgacacc ggcaucaccc      180

cccugagccc cagccacauc gugaacgaca ccgacagcaa cgugagcgag cagcagagcu      240

uccugguggu gguggccgug gacuucggca ccaccagcag cggcuacgcc uacagcuuca      300

ccaaggagcc cgagugcauc cacgugauga gaagauggga gggcggcgac cccggcguga      360

gcaaccagaa gacccccacc accauccugc ugacccccga gagaaaguuc cacagcuucg      420

gcuacgccgc cagagacuuc uaccacgacc uggaccccaa cgaggccaag caguggcugu      480

accuggagaa guucaagaug aagcugcaca ccaccggcga ccugaccaug gacaccgacc      540

ugaccgccgc caacggcaag aaggugaagg cccuggagau cuucgccuac gcccugcagu      600

acuucaagga gcaggcccug aaggagcuga gcgaccaggc cggcagcgag uucgagaaca      660

gcgacgugag augggugauc accgugcccg ccaucuggaa gcagcccgcc aagcaguuca      720

ugagacaggc cgccuaccag gccggccugg ccagccccga gaacagcgag cagcugauca      780

ucgcccugga gcccgaggcc gccagcaucu acugcagaaa gcugagacug caccagauga      840

ucgagcugag cagcaaggcc gccgugaacg gcuacagcgg cagcgacacc gugggcgccg      900

gcuucaccca ggccaaggag cacaucagaa gaaacagaca gagcagaacc uuccuggugg      960

agaacgugau cggcgagauc uggagcgagc uggaggaggg cgacaaguac gugguggugg     1020

acagcggcgg cggcaccgug gaccugaccg ugcaccagau cagacugccc gagggccacc     1080

ugaaggagcu guacaaggcc accggcggcc ccuacggcag ccugggcgug gacuacgagu     1140

ucgagaagcu gcuguacaag aucuucggcg aggacuucau cgagcaguuc aagaucaaga     1200

gacccgccgc cuggguggac cugaugaucg ccuucgagag cagaaagaga gccgccgccc     1260

ccgacagaac caacccccug aacaucaccc ugcccuucag cuucaucgac uacuacaaga     1320

aguucagagg ccacagcgug gagcacgccc ugagaaagag caacguggac uucgugaagu     1380

ggagcagcca gggcaugcug agaaugagcc ccgacgccau gaacgcccug uucaagccca     1440

ccaucgacag caucaucgag caccugagag accuguucca gaagcccgag gugagcaccg     1500

ugaaguuccu guuccuggug ggcggcuucg ccgaggcccc ccugcugcag caggccgugc     1560

aggccgccuu cggcgaccag ugcagaauca ucauccccca ggacgugggc cugaccaucc     1620

ugaagggcgc cgugcuguuc ggccuggacc ccgccgugau caaggugaga agaagccccc     1680

ugaccuacgg cgugggcgug cugaacagau acguggaggg caagcacccc cccgagaagc     1740

ugcuggugaa ggacggcacc agauggugca ccgacguguu cgacaaguuc aucagcgccg     1800

accagagcgu ggcccugggc gagcugguga agagaagcua cacccccgcc aagcccagcc     1860

agcuggugau cgugaucaac aucuacagca gcgagcacga caacgugagc uucaucaccg     1920

accccggcgu gaagaagugc ggcacccuga gacuggaccu gaccggcacc agcggcaccg     1980

ccgugcccgc cagaagagag auccagaccc ugaugcaguu cggcgacacc gagaucaagg     2040

ccaccgccau cgacaucgcc accagcaaga gcgugaaggu gggcaucgac uuccugaacu     2100

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  4236
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt4)

<400>  4236
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuggccgugc ccgagauggg ccugcagggc cuguacaucg      120

gcagcagccc cgagagaagc cccgugccca gcccccccgg cagccccaga acccaggaga      180

gcugcggcau cgccccccug acccccagcc agagccccaa gcccgaggug agagcccccc      240

agcaggccag cuucagcgug gugguggcca ucgacuucgg caccaccagc agcggcuacg      300

ccuucagcuu cgccagcgac cccgaggcca uccacaugau gagaaagugg gagggcggcg      360

accccggcgu ggcccaccag aagaccccca ccugccugcu gcugaccccc gagggcgccu      420

uccacagcuu cggcuacacc gccagagacu acuaccacga ccuggacccc gaggaggcca      480

gagacuggcu guacuucgag aaguucaaga ugaagaucca cagcgccacc gaccugaccc      540

ugaagaccca gcuggaggcc gugaacggca agaccaugcc cgcccuggag guguucgccc      600

acgcccugag auucuucaga gagcacgccc ugcaggagcu gagagagcag agccccagcc      660

ugcccgagaa ggacaccgug agaugggugc ugaccgugcc cgccaucugg aagcagcccg      720

ccaagcaguu caugagagag gccgccuacc uggccggccu ggugagcaga gagaacgccg      780

agcagcugcu gaucgcccug gagcccgagg ccgccagcgu guacugcaga aagcugagac      840

ugcaccagcu gcuggaccug agcggcagag cccccggcgg cggcagacug ggcgagagaa      900

gaagcaucga cagcagcuuc agacaggcca gagagcagcu gagaagaagc agacacagca      960

gaaccuuccu gguggagagc ggcgugggcg agcugugggc cgagaugcag gccggcgaca     1020

gauacguggu ggccgacugc ggcggcggca ccguggaccu gaccgugcac cagcuggagc     1080

agccccacgg cacccugaag gagcuguaca aggccagcgg cggccccuac ggcgccgugg     1140

gcguggaccu ggccuucgag cagcugcugu gcagaaucuu cggcgaggac uucaucgcca     1200

ccuucaagag acagagaccc gccgccuggg uggaccugac caucgccuuc gaggccagaa     1260

agagaaccgc cggcccccac agagccggcg cccugaacau cagccugccc uucagcuuca     1320

ucgacuucua cagaaagcag agaggccaca acguggagac cgcccugaga agaagcagcg     1380

ugaacuucgu gaaguggagc agccagggca ugcugagaau gagcugcgag gccaugaacg     1440

agcuguucca gcccaccgug agcggcauca uccagcacau cgaggcccug cuggccagac     1500

ccgaggugca gggcgugaag cugcuguucc uggugggcgg cuucgccgag agcgccgugc     1560

ugcagcacgc cgugcaggcc gcccugggcg ccagaggccu gagaguggug gugccccacg     1620

acgugggccu gaccauccug aagggcgccg ugcuguucgg ccaggccccc ggcgugguga     1680

gagugagaag aagcccccug accuacggcg ugggcgugcu gaacagauuc gugcccggca     1740

gacacccccc cgagaagcug cuggugagag acggcagaag auggugcacc gacguguucg     1800

agagauucgu ggccgccgag cagagcgugg cccugggcga ggaggugaga agaagcuacu     1860

gccccgccag acccggccag agaagagugc ugaucaaccu guacugcugc gccgccgagg     1920

acgccagauu caucaccgac cccggcguga gaaagugcgg cgcccugagc cuggagcugg     1980

agcccgccga cugcggccag gacaccgccg gcgccccccc cggcagaaga gagaucagag     2040

ccgccaugca guucggcgac accgagauca aggugaccgc cguggacgug agcaccaaca     2100

gaagcgugag agccagcauc gacuuccuga gcaacugagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  4237
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt4)

<400>  4237
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagagaga ugaccauccu gggcagcgcc gugcugaccc      120

ugcugcuggc cggcuaccug gcccagcagu accugccccu gcccaccccc aaggugaucg      180

gcaucgaccu gggcaccacc uacugcagcg ugggcguguu cuuccccggc accggcaagg      240

ugaaggugau ccccgacgag aacggccaca ucagcauccc cagcauggug agcuucaccg      300

acaacgacgu guacgugggc uacgagagcg uggagcuggc cgacagcaac ccccagaaca      360

ccaucuacga cgccaagaga uucaucggca agaucuucac cgccgaggag cuggaggccg      420

agaucggcag auaccccuuc aaggugcuga acaagaacgg caugguggag uucagcguga      480

ccagcaacga gaccaucacc gugagccccg aguacguggg cagcagacug cugcugaagc      540

ugaaggagau ggccgaggcc uaccugggca ugcccguggc caacgccgug aucagcgugc      600

ccgccgaguu cgaccugaag cagagaaaca gcaccaucga ggccgccaac cuggccggcc      660

ugaagauccu gagagugauc aacgagccca ccgccgccgc cauggccuac ggccugcaca      720

aggccgacgu guuccacgug cuggugaucg accugggcgg cggcacccug gacgugagcc      780

ugcugaacaa gcagggcggc auguuccuga ccagagccau gagcggcaac aacaagcugg      840

gcggccagga cuucaaccag agacugcugc aguaccugua caagcagauc uaccagaccu      900

acggcuucgu gcccagcaga aaggaggaga uccacagacu gagacaggcc guggagaugg      960

ugaagcugaa ccugacccug caccagagcg cccagcugag cgugcugcug accguggagg     1020

agcaggacag aaaggagccc cacagcagcg acaccgagcu gcccaaggac aagcugagca     1080

gcgccgacga ccacagagug aacagcggcu ucggcagagg ccugagcgac aagaagagcg     1140

gcgagagcca ggugcuguuc gagaccgaga ucagcagaaa gcuguucgac acccugaacg     1200

aggaccuguu ccagaagauc cuggugccca uccagcaggu gcugaaggag ggccaccugg     1260

agaagaccga gaucgacgag guggugcugg ugggcggcag caccagaauc cccagaauca     1320

gacaggugau ccaggaguuc uucggcaagg accccaacac cagcguggac cccgaccugg     1380

ccguggugac cggcguggcc auccaggccg gcaucgacgg cggcagcugg ccccugcagg     1440

ugagcgcccu ggagaucccc aacaagcacc ugcagaagac caacuucaac ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4238
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt4)

<400>  4238
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgccaucg gcgugcaccu gggcugcacc agcgccugcg      120

uggccgugua caaggacggc agagccggcg ugguggccaa cgacgccggc gacagaguga      180

cccccgccgu gguggccuac agcgagaacg aggagaucgu gggccuggcc gccaagcaga      240

gcagaaucag aaacaucagc aacaccguga ugaaggugaa gcagauccug ggcagaagca      300

gcagcgaccc ccaggcccag aaguacaucg ccgagagcaa gugccuggug aucgagaaga      360

acggcaagcu gagauacgag aucgacaccg gcgaggagac caaguucgug aaccccgagg      420

acguggccag acugaucuuc agcaagauga aggagaccgc ccacagcgug cugggcagcg      480

acgccaacga cguggugauc accgugcccu ucgacuucgg cgagaagcag aagaacgccc      540

ugggcgaggc cgccagagcc gccggcuuca acgugcugag acugauccac gagcccagcg      600

ccgcccugcu ggccuacggc aucggccagg acagccccac cggcaagagc aacauccugg      660

uguucaagcu gggcggcacc agccugagcc ugagcgugau ggaggugaac agcggcaucu      720

acagagugcu gagcaccaac accgacgaca acaucggcgg cgcccacuuc accgagaccc      780

uggcccagua ccuggccagc gaguuccaga gaagcuucaa gcacgacgug agaggcaacg      840

ccagagccau gaugaagcug accaacagcg ccgagguggc caagcacagc cugagcaccc      900

ugggcagcgc caacugcuuc cuggacagcc uguacgaggg ccaggacuuc gacugcaacg      960

ugagcagagc cagauucgag cugcugugca gcccccuguu caacaagugc aucgaggcca     1020

ucagaggccu gcuggaccag aacggcuuca ccgccgacga caucaacaag guggugcugu     1080

gcggcggcag cagcagaauc cccaagcugc agcagcugau caaggaccug uuccccgccg     1140

uggagcugcu gaacagcauc ccccccgacg aggugauccc caucggcgcc gccaucgagg     1200

ccggcauccu gaucggcaag gagaaccugc ugguggagga cagccugaug aucgagugca     1260

gcgccagaga cauccuggug aagggcgugg acgagagcgg cgccagcaga uucaccgugc     1320

uguuccccag cggcaccccc cugcccgcca gaagacagca cacccugcag gcccccggca     1380

gcaucagcag cgugugccug gagcuguacg agagcgacgg caagaacagc gccaaggagg     1440

agaccaaguu cgcccaggug gugcugcagg accuggacaa gaaggagaac ggccugagag     1500

acauccuggc cgugcugacc augaagagag acggcagccu gcacgugacc ugcaccgacc     1560

aggagaccgg caagugcgag gccaucagca ucgagaucgc cagcugagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  4239
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt4)

<400>  4239
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggugg gccuggacgu gggcagccag agcugcuaca      120

ucgccguggc cagagccggc ggcaucgaga ccaucgccaa cgaguucagc gacagaugca      180

cccccagcgu gaucagcuuc ggcagcaaga acagaaccau cggcguggcc gccaagaacc      240

agcagaucac ccacgccaac aacaccguga gcaacuucaa gagauuccac ggcagagccu      300

ucaacgaccc cuucauccag aaggagaagg agaaccugag cuacgaccug gugccccuga      360

agaacggcgg cgugggcauc aaggugaugu acaugggcga ggagcaccug uucagcgugg      420

agcagaucac cgccaugcug cugaccaagc ugaaggagac cgccgagaac agccugaaga      480

agcccgugac cgacugcgug aucagcgugc ccagcuucuu caccgacgcc gagagaagaa      540

gcgugcugga cgccgcccag aucgugggcc ugaacugccu gagacugaug aacgacauga      600

ccgccguggc ccugaacuac ggcaucuaca agcaggaccu gcccagccug gacgagaagc      660

ccagaaucgu gguguucgug gacaugggcc acagcgccuu ccaggugagc gccugcgccu      720

ucaacaaggg caagcugaag gugcugggca ccgccuucga ccccuuccug ggcggcaaga      780

acuucgacga gaagcuggug gagcacuucu gcgccgaguu caagaccaag uacaagcugg      840

acgccaagag caagaucaga gcccugcuga gacuguacca ggagugcgag aagcugaaga      900

agcugaugag cagcaacagc accgaccugc cccugaacau cgagugcuuc augaacgaca      960

aggacgugag cggcaagaug aacagaagcc aguucgagga gcugugcgcc gagcugcugc     1020

agaagaucga ggugccccug uacagccugc uggagcagac ccaccugaag guggaggacg     1080

ugagcgccgu ggagaucgug ggcggcgcca ccagaauccc cgccgugaag gagagaaucg     1140

ccaaguucuu cggcaaggac aucagcacca cccugaacgc cgacgaggcc guggccagag     1200

gcugcgcccu gcagugcgcc auccugagcc ccgccuucaa ggugagagag uucagcguga     1260

ccgacgccgu gcccuucccc aucagccuga ucuggaacca cgacagcgag gacaccgagg     1320

gcgugcacga gguguucagc agaaaccacg ccgcccccuu cagcaaggug cugaccuucc     1380

ugagaagagg ccccuucgag cuggaggccu ucuacagcga cccccagggc gugcccuacc     1440

ccgaggccaa gaucggcaga uucguggugc agaacgugag cgcccagaag gacggcgaga     1500

agagcagagu gaaggugaag gugagaguga acacccacgg caucuucacc aucagcaccg     1560

ccagcauggu ggagaaggug cccaccgagg agaacgagau gagcagcgag gccgacaugg     1620

agugccugaa ccagagaccc cccgagaacc ccgacaccga caagaacgug cagcaggaca     1680

acagcgaggc cggcacccag ccccaggugc agaccgacgc ccagcagacc agccagagcc     1740

cccccagccc cgagcugacc agcgaggaga acaagauccc cgacgccgac aaggccaacg     1800

agaagaaggu ggaccagccc cccgaggcca agaagcccaa gaucaaggug gugaacgugg     1860

agcugcccau cgaggccaac cugguguggc agcugggcaa ggaccugcug aacauguaca     1920

ucgagaccga gggcaagaug aucaugcagg acaagcugga gaaggagaga aacgacgcca     1980

agaacgccgu ggaggaguac guguacgagu ucagagacaa gcugugcggc cccuacgaga     2040

aguucaucug cgagcaggac caccagaacu uccugagacu gcugaccgag accgaggacu     2100

ggcuguacga ggagggcgag gaccaggcca agcaggccua cguggacaag cuggaggagc     2160

ugaugaagau cggcaccccc gugaagguga gauuccagga ggccgaggag agacccaaga     2220

uguucgagga gcugggccag agacugcagc acuacgccaa gaucgccgcc gacuucagaa     2280

acaaggacga gaaguacaac cacaucgacg agagcgagau gaagaaggug gagaagagcg     2340

ugaacgaggu gauggagugg augaacaacg ugaugaacgc ccaggccaag aagagccugg     2400

accaggaccc cguggugaga gcccaggaga ucaagaccaa gaucaaggag cugaacaaca     2460

ccugcgagcc cguggugacc cagcccaagc ccaagaucga gagccccaag cuggagagaa     2520

cccccaacgg ccccaacauc gacaagaagg aggaggaccu ggaggacaag aacaacuucg     2580

gcgccgagcc cccccaccag aacggcgagu gcuaccccaa cgagaagaac agcgugaaca     2640

uggaccugga cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  4240
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt4)

<400>  4240
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg ugagaagaca gagacccaga agaagagugu      120

gcugggcccu gguggccgug cugcuggccg accugcuggc ccugagcgac acccuggccg      180

ugaugagcgu ggaccugggc agcgagagca ugaagguggc caucgugaag cccggcgugc      240

ccauggagau cgugcugaac aaggagagca gaagaaagac ccccgugauc gugacccuga      300

aggagaacga gagauucuuc ggcgacagcg ccgccagcau ggccaucaag aaccccaagg      360

ccacccugag auacuuccag caccugcugg gcaagcaggc cgacaacccc cacguggccc      420

uguaccaggc cagauucccc gagcacgagc ugaccuucga cccccagaga cagaccgugc      480

acuuccagau cagcagccag cugcaguuca gccccgagga ggugcugggc auggugcuga      540

acuacagcag aagccuggcc gaggacuucg ccgagcagcc caucaaggac gccgugauca      600

ccgugcccgu guucuucaac caggccgaga gaagagccgu gcugcaggcc gccagaaugg      660

ccggccugaa ggugcugcag cugaucaacg acaacaccgc caccgcccug agcuacggcg      720

uguucagaag aaaggacauc aacaccaccg cccagaacau cauguucuac gacaugggca      780

gcggcagcac cgugugcacc aucgugaccu accagauggu gaagaccaag gaggccggca      840

ugcagcccca gcugcagauc agaggcgugg gcuucgacag aacccugggc ggccuggaga      900

uggagcugag acugagagag agacuggccg gccuguucaa cgagcagaga aagggccaga      960

gagccaagga cgugagagag aaccccagag ccauggccaa gcugcugaga gaggccaaca     1020

gacugaagac cgugcugagc gccaacgccg accacauggc ccagaucgag ggccugaugg     1080

acgacgugga cuucaaggcc aaggugacca gaguggaguu cgaggagcug ugcgccgacc     1140

uguucgagag agugcccggc cccgugcagc aggcccugca gagcgccgag augagccugg     1200

acgagaucga gcaggugauc cuggugggcg gcgccaccag agugcccaga gugcaggagg     1260

ugcugcugaa ggccgugggc aaggaggagc ugggcaagaa caucaacgcc gacgaggccg     1320

ccgccauggg cgccguguac caggccgccg cccugagcaa ggccuucaag gugaagcccu     1380

ucguggugag agacgccgug guguacccca uccuggugga guucaccaga gagguggagg     1440

aggagcccgg cauccacagc cugaagcaca acaagagagu gcuguucagc agaaugggcc     1500

ccuaccccca gagaaaggug aucaccuuca acagauacag ccacgacuuc aacuuccaca     1560

ucaacuacgg cgaccugggc uuccugggcc ccgaggaccu gagaguguuc ggcagccaga     1620

accugaccac cgugaagcug aagggcgugg gcgacagcuu caagaaguac cccgacuacg     1680

agagcaaggg caucaaggcc cacuucaacc uggacgagag cggcgugcug agccuggaca     1740

gaguggagag cguguucgag acccuggugg aggacagcgc cgaggaggag agcacccuga     1800

ccaagcuggg caacaccauc agcagccugu ucggcggcgg caccaccccc gacgccaagg     1860

agaacggcac cgacaccgug caggaggagg aggagagccc cgccgagggc agcaaggacg     1920

agcccggcga gcagguggag cugaaggagg aggccgaggc ccccguggag gacggcagcc     1980

agcccccccc ccccgagccc aagggcgacg ccacccccga gggcgagaag gccaccgaga     2040

aggagaacgg cgacaagagc gaggcccaga agcccagcga gaaggccgag gccggccccg     2100

agggcguggc ccccgccccc gagggcgaga agaagcagaa gcccgccaga aagagaagaa     2160

ugguggagga gaucggcgug gagcuggugg ugcuggaccu gcccgaccug cccgaggaca     2220

agcuggccca gagcgugcag aagcugcagg accugacccu gagagaccug gagaagcagg     2280

agagagagaa ggccgccaac agccuggagg ccuucaucuu cgagacccag gacaagcugu     2340

accagcccga guaccaggag gugagcaccg aggagcagag agaggagauc agcggcaagc     2400

ugagcgccgc cagcaccugg cuggaggacg agggcguggg cgccaccacc gugaugcuga     2460

aggagaagcu ggccgagcug agaaagcugu gccagggccu guucuucaga guggaggaga     2520

gaaagaagug gcccgagaga cugagcgccc uggacaaccu gcugaaccac agcagcaugu     2580

uccugaaggg cgccagacug auccccgaga uggaccagau cuucaccgag guggagauga     2640

ccacccugga gaaggugauc aacgagaccu gggccuggaa gaacgccacc cuggccgagc     2700

aggccaagcu gcccgccacc gagaagcccg ugcugcugag caaggacauc gaggccaaga     2760

ugauggcccu ggacagagag gugcaguacc ugcugaacaa ggccaaguuc accaagccca     2820

gacccagacc caaggacaag aacggcacca gagccgagcc cccccugaac gccagcgcca     2880

gcgaccaggg cgagaaggug aucccccccg ccggccagac cgaggacgcc gagcccauca     2940

gcgagcccga gaagguggag accggcagcg agcccggcga caccgagccc cuggagcugg     3000

gcggccccgg cgccgagccc gagcagaagg agcagagcac cggccagaag agaccccuga     3060

agaacgacga gcugugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4241
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt4)

<400>  4241
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaga cccagaccca ggaccagccc auggaggagg      120

aggaggugga gaccuucgcc uuccaggccg agaucgccca gcugaugagc cugaucauca      180

acaccuucua cagcaacaag gagaucuucc ugagagagcu gaucagcaac agcagcgacg      240

cccuggacaa gaucagauac gagagccuga ccgaccccag caagcuggac agcggcaagg      300

agcugcacau caaccugauc cccaacaagc aggacagaac ccugaccauc guggacaccg      360

gcaucggcau gaccaaggcc gaccugauca acaaccuggg caccaucgcc aagagcggca      420

ccaaggccuu cauggaggcc cugcaggccg gcgccgacau cagcaugauc ggccaguucg      480

gcgugggcuu cuacagcgcc uaccuggugg ccgagaaggu gaccgugauc accaagcaca      540

acgacgacga gcaguacgcc ugggagagca gcgccggcgg cagcuucacc gugagaaccg      600

acaccggcga gcccaugggc agaggcacca aggugauccu gcaccugaag gaggaccaga      660

ccgaguaccu ggaggagaga agaaucaagg agaucgugaa gaagcacagc caguucaucg      720

gcuaccccau cacccuguuc guggagaagg agagagacaa ggaggugagc gacgacgagg      780

ccgaggagaa ggaggacaag gaggaggaga aggagaagga ggagaaggag agcgaggaca      840

agcccgagau cgaggacgug ggcagcgacg aggaggagga gaagaaggac ggcgacaaga      900

agaagaagaa gaagaucaag gagaaguaca ucgaccagga ggagcugaac aagaccaagc      960

ccaucuggac cagaaacccc gacgacauca ccaacgagga guacggcgag uucuacaaga     1020

gccugaccaa cgacugggag gaccaccugg ccgugaagca cuucagcgug gagggccagc     1080

uggaguucag agcccugcug uucgugccca gaagagcccc cuucgaccug uucgagaaca     1140

gaaagaagaa gaacaacauc aagcuguacg ugagaagagu guucaucaug gacaacugcg     1200

aggagcugau ccccgaguac cugaacuuca ucagaggcgu gguggacagc gaggaccugc     1260

cccugaacau cagcagagag augcugcagc agagcaagau ccugaaggug aucagaaaga     1320

accuggugaa gaagugccug gagcuguuca ccgagcuggc cgaggacaag gagaacuaca     1380

agaaguucua cgagcaguuc agcaagaaca ucaagcuggg cauccacgag gacagccaga     1440

acagaaagaa gcugagcgag cugcugagau acuacaccag cgccagcggc gacgagaugg     1500

ugagccugaa ggacuacugc accagaauga aggagaacca gaagcacauc uacuacauca     1560

ccggcgagac caaggaccag guggccaaca gcgccuucgu ggagagacug agaaagcacg     1620

gccuggaggu gaucuacaug aucgagccca ucgacgagua cugcgugcag cagcugaagg     1680

aguucgaggg caagacccug gugagcguga ccaaggaggg ccuggagcug cccgaggacg     1740

aggaggagaa gaagaagcag gaggagaaga agaccaaguu cgagaaccug ugcaagauca     1800

ugaaggacau ccuggagaag aagguggaga aggugguggu gagcaacaga cuggugacca     1860

gccccugcug caucgugacc agcaccuacg gcuggaccgc caacauggag agaaucauga     1920

aggcccaggc ccugagagac aacagcacca ugggcuacau ggccgccaag aagcaccugg     1980

agaucaaccc cgaccacagc aucaucgaga cccugagaca gaaggccgag gccgacaaga     2040

acgacaagag cgugaaggac cuggugaucc ugcuguacga gaccgcccug cugagcagcg     2100

gcuucagccu ggaggacccc cagacccacg ccaacagaau cuacagaaug aucaagcugg     2160

gccugggcau cgacgaggac gaccccaccg ccgacgacac cagcgccgcc gugaccgagg     2220

agaugccccc ccuggagggc gacgacgaca ccagcagaau ggaggaggug gacugaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  4242
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt4)

<400>  4242
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcagca agcuggacag cggcaagggc cugcacauca      120

accuggugcc caacaagcag aaccagaccc ugaccaucgu ggacaccaga aucggcauga      180

ccaagaccga ccugaucaac aaccugggca ccgugaccaa gagcggcacc aaggccuuca      240

uggaggcccu gcaggccgac gccgacauca gcaugaucgg ccacuucggc gugggcuucu      300

acagcgccua ccugguggcc aagaagguga ccgugaucag caagcacaac aacgacgagc      360

aguacaccug ggagagcagc gccggcggca gcuucaccgu gagaaccgac gagugaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  4243
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt4)

<400>  4243
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggagg ugcaccacgg cgaggaggag guggagaccu      120

ucgccuucca ggccgagauc gcccagcuga ugagccugau caucaacacc uucuacagca      180

acaaggagau cuuccugaga gagcugauca gcaacgccag cgacgcccug gacaagauca      240

gauacgagag ccugaccgac cccagcaagc uggacagcgg caaggagcug aagaucgaca      300

ucauccccaa cccccaggag agaacccuga cccuggugga caccggcauc ggcaugacca      360

aggccgaccu gaucaacaac cugggcacca ucgccaagag cggcaccaag gccuucaugg      420

aggcccugca ggccggcgcc gacaucagca ugaucggcca guucggcgug ggcuucuaca      480

gcgccuaccu gguggccgag aagguggugg ugaucaccaa gcacaacgac gacgagcagu      540

acgccuggga gagcagcgcc ggcggcagcu ucaccgugag agccgaccac ggcgagccca      600

ucggcagagg caccaaggug auccugcacc ugaaggagga ccagaccgag uaccuggagg      660

agagaagagu gaaggaggug gugaagaagc acagccaguu caucggcuac cccaucaccc      720

uguaccugga gaaggagaga gagaaggaga ucagcgacga cgaggccgag gaggagaagg      780

gcgagaagga ggaggaggac aaggacgacg aggagaagcc caagaucgag gacgugggca      840

gcgacgagga ggacgacagc ggcaaggaca agaagaagaa gaccaagaag aucaaggaga      900

aguacaucga ccaggaggag cugaacaaga ccaagcccau cuggaccaga aaccccgacg      960

acaucaccca ggaggaguac ggcgaguucu acaagagccu gaccaacgac ugggaggacc     1020

accuggccgu gaagcacuuc agcguggagg gccagcugga guucagagcc cugcuguuca     1080

uccccagaag agcccccuuc gaccuguucg agaacaagaa gaagaagaac aacaucaagc     1140

uguacgugag aagaguguuc aucauggaca gcugcgacga gcugaucccc gaguaccuga     1200

acuucaucag aggcguggug gacagcgagg accugccccu gaacaucagc agagagaugc     1260

ugcagcagag caagauccug aaggugauca gaaagaacau cgugaagaag ugccuggagc     1320

uguucagcga gcuggccgag gacaaggaga acuacaagaa guucuacgag gccuucagca     1380

agaaccugaa gcugggcauc cacgaggaca gcaccaacag aagaagacug agcgagcugc     1440

ugagauacca caccagccag agcggcgacg agaugaccag ccugagcgag uacgugagca     1500

gaaugaagga gacccagaag agcaucuacu acaucaccgg cgagagcaag gagcaggugg     1560

ccaacagcgc cuucguggag agagugagaa agagaggcuu cgagguggug uacaugaccg     1620

agcccaucga cgaguacugc gugcagcagc ugaaggaguu cgacggcaag agccugguga     1680

gcgugaccaa ggagggccug gagcugcccg aggacgagga ggagaagaag aagauggagg     1740

agagcaaggc caaguucgag aaccugugca agcugaugaa ggagauccug gacaagaagg     1800

uggagaaggu gaccaucagc aacagacugg ugagcagccc cugcugcauc gugaccagca     1860

ccuacggcug gaccgccaac auggagagaa ucaugaaggc ccaggcccug agagacaaca     1920

gcaccauggg cuacaugaug gccaagaagc accuggagau caaccccgac caccccaucg     1980

uggagacccu gagacagaag gccgaggccg acaagaacga caaggccgug aaggaccugg     2040

uggugcugcu guucgagacc gcccugcuga gcagcggcuu cagccuggag gacccccaga     2100

cccacagcaa cagaaucuac agaaugauca agcugggccu gggcaucgac gaggacgagg     2160

uggccgccga ggagcccaac gccgccgugc ccgacgagau ccccccccug gagggcgacg     2220

aggacgccag cagaauggag gagguggacu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  4244
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt4)

<400>  4244
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agagcccugu gggugcuggg ccugugcugc gugcugcuga      120

ccuucggcag cgugagagcc gacgacgagg uggacgugga cggcaccgug gaggaggacc      180

ugggcaagag cagagagggc agcagaaccg acgacgaggu ggugcagaga gaggaggagg      240

ccauccagcu ggacggccug aacgccagcc agaucagaga gcugagagag aagagcgaga      300

aguucgccuu ccaggccgag gugaacagaa ugaugaagcu gaucaucaac agccuguaca      360

agaacaagga gaucuuccug agagagcuga ucagcaacgc cagcgacgcc cuggacaaga      420

ucagacugau cagccugacc gacgagaacg cccugagcgg caacgaggag cugaccguga      480

agaucaagug cgacaaggag aagaaccugc ugcacgugac cgacaccggc gugggcauga      540

ccagagagga gcuggugaag aaccugggca ccaucgccaa gagcggcacc agcgaguucc      600

ugaacaagau gaccgaggcc caggaggacg gccagagcac cagcgagcug aucggccagu      660

ucggcguggg cuucuacagc gccuuccugg uggccgacaa ggugaucgug accagcaagc      720

acaacaacga cacccagcac aucugggaga gcgacagcaa cgaguucagc gugaucgccg      780

accccagagg caacacccug ggcagaggca ccaccaucac ccuggugcug aaggaggagg      840

ccagcgacua ccuggagcug gacaccauca agaaccuggu gaagaaguac agccaguuca      900

ucaacuuccc caucuacgug uggagcagca agaccgagac cguggaggag cccauggagg      960

aggaggaggc cgccaaggag gagaaggagg agagcgacga cgaggccgcc guggaggagg     1020

aggaggagga gaagaagccc aagaccaaga agguggagaa gaccgugugg gacugggagc     1080

ugaugaacga caucaagccc aucuggcaga gacccagcaa ggagguggag gaggacgagu     1140

acaaggccuu cuacaagagc uucagcaagg agagcgacga ccccauggcc uacauccacu     1200

ucaccgccga gggcgaggug accuucaaga gcauccuguu cgugcccacc agcgccccca     1260

gaggccuguu cgacgaguac ggcagcaaga agagcgacua caucaagcug uacgugagaa     1320

gaguguucau caccgacgac uuccacgaca ugaugcccaa guaccugaac uucgugaagg     1380

gcguggugga cagcgacgac cugccccuga acgugagcag agagacccug cagcagcaca     1440

agcugcugaa ggugaucaga aagaagcugg ugagaaagac ccuggacaug aucaagaaga     1500

ucgccgacga caaguacaac gacaccuucu ggaaggaguu cggcaccaac aucaagcugg     1560

gcgugaucga ggaccacagc aacagaacca gacuggccaa gcugcugaga uuccagagca     1620

gccaccaccc caccgacauc accagccugg accaguacgu ggagagaaug aaggagaagc     1680

aggacaagau cuacuucaug gccggcagca gcagaaagga ggccgagagc agccccuucg     1740

uggagagacu gcugaagaag ggcuacgagg ugaucuaccu gaccgagccc guggacgagu     1800

acugcaucca ggcccugccc gaguucgacg gcaagagauu ccagaacgug gccaaggagg     1860

gcgugaaguu cgacgagagc gagaagacca aggagagcag agaggccgug gagaaggagu     1920

ucgagccccu gcugaacugg augaaggaca aggcccugaa ggacaagauc gagaaggccg     1980

uggugagcca gagacugacc gagagccccu gcgcccuggu ggccagccag uacggcugga     2040

gcggcaacau ggagagaauc augaaggccc aggccuacca gaccggcaag gacaucagca     2100

ccaacuacua cgccagccag aagaagaccu ucgagaucaa ccccagacac ccccugauca     2160

gagacaugcu gagaagaauc aaggaggacg aggacgacaa gaccgugcug gaccuggccg     2220

uggugcuguu cgagaccgcc acccugagaa gcggcuaccu gcugcccgac accaaggccu     2280

acggcgacag aaucgagaga augcugagac ugagccugaa caucgacccc gacgccaagg     2340

uggaggagga gcccgaggag gagcccgagg agaccgccga ggacaccacc gaggacaccg     2400

agcaggacga ggacgaggag auggacgugg gcaccgacga ggaggaggag accgccaagg     2460

agagcaccgc cgagaaggac gagcugugag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  4245
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt4)

<400>  4245
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagagagc ugagagcccu gcugcugugg ggcagaagac      120

ugagaccccu gcugagagcc cccgcccugg ccgccgugcc cggcggcaag cccauccugu      180

gccccagaag aaccaccgcc cagcugggcc ccagaagaaa ccccgccugg agccugcagg      240

ccggcagacu guucagcacc cagaccgccg aggacaagga ggagccccug cacagcauca      300

ucagcagcac cgagagcgug cagggcagca ccagcaagca cgaguuccag gccgagacca      360

agaagcugcu ggacaucgug gccagaagcc uguacagcga gaaggaggug uucaucagag      420

agcugaucag caacgccagc gacgcccugg agaagcugag acacaagcug gugagcgacg      480

gccaggcccu gcccgagaug gagauccacc ugcagaccaa cgccgagaag ggcaccauca      540

ccauccagga caccggcauc ggcaugaccc aggaggagcu ggugagcaac cugggcacca      600

ucgccagaag cggcagcaag gccuuccugg acgcccugca gaaccaggcc gaggccagca      660

gcaagaucau cggccaguuc ggcgugggcu ucuacagcgc cuucauggug gccgacagag      720

uggaggugua cagcagaagc gccgcccccg gcagccuggg cuaccagugg cugagcgacg      780

gcagcggcgu guucgagauc gccgaggcca gcggcgugag aaccggcacc aagaucauca      840

uccaccugaa gagcgacugc aaggaguuca gcagcgaggc cagagugaga gacgugguga      900

ccaaguacag caacuucgug agcuuccccc uguaccugaa cggcagaaga augaacaccc      960

ugcaggccau cuggaugaug gaccccaagg acgugagaga guggcagcac gaggaguucu     1020

acagauacgu ggcccaggcc cacgacaagc ccagauacac ccugcacuac aagaccgacg     1080

ccccccugaa caucagaagc aucuucuacg ugcccgacau gaagcccagc auguucgacg     1140

ugagcagaga gcugggcagc agcguggccc uguacagcag aaaggugcug auccagacca     1200

aggccaccga cauccugccc aaguggcuga gauucaucag aggcguggug gacagcgagg     1260

acaucccccu gaaccugagc agagagcugc ugcaggagag cgcccugauc agaaagcuga     1320

gagacgugcu gcagcagaga cugaucaagu ucuucaucga ccagagcaag aaggacgccg     1380

agaaguacgc caaguucuuc gaggacuacg gccuguucau gagagagggc aucgugaccg     1440

ccaccgagca ggaggugaag gaggacaucg ccaagcugcu gagauacgag agcagcgccc     1500

ugcccagcgg ccagcugacc agccugagcg aguacgccag cagaaugaga gccggcacca     1560

gaaacaucua cuaccugugc gcccccaaca gacaccuggc cgagcacagc cccuacuacg     1620

aggccaugaa gaagaaggac accgaggugc uguucugcuu cgagcaguuc gacgagcuga     1680

cccugcugca ccugagagag uucgacaaga agaagcugau cagcguggag accgacaucg     1740

ugguggacca cuacaaggag gagaaguucg aggacagaag ccccgccgcc gagugccuga     1800

gcgagaagga gaccgaggag cugauggccu ggaugagaaa cgugcugggc agcagaguga     1860

ccaacgugaa ggugacccug agacuggaca cccaccccgc cauggugacc gugcuggaga     1920

ugggcgccgc cagacacuuc cugagaaugc agcagcuggc caagacccag gaggagagag     1980

cccagcugcu gcagcccacc cuggagauca accccagaca cgcccugauc aagaagcuga     2040

accagcugag agccagcgag cccggccugg cccagcugcu gguggaccag aucuacgaga     2100

acgccaugau cgccgccggc cugguggacg accccagagc cauggugggc agacugaacg     2160

agcugcuggu gaaggcccug gagagacacu gaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  4246
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt4)

<400>  4246
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagauca gcagccugcc cacccagcug uucaagugcu      120

gcuucugcga cuuccugaag gugaagaugc acaccaugag cagcagccac cuguucuacc      180

uggcccugug ccugcugacc uucaccagca gcgccaccgc cggccccgag acccugugcg      240

gcgccgagcu gguggacgcc cugcaguucg ugugcggcga cagaggcuuc uacuucaaca      300

agcccaccgg cuacggcagc agcagcagaa gagcccccca gaccggcauc guggacgagu      360

gcugcuucag aagcugcgac cugagaagac uggagaugua cugcgccccc cugaagcccg      420

ccaagagcgc cagaagcgug agagcccaga gacacaccga caugcccaag acccagaagg      480

aggugcaccu gaagaacgcc agcagaggca gcgccggcaa caagaacuac agaaugugag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  4247
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt4)

<400>  4247
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca ugggcaagag caugcuggug cugcugaccu      120

uccuggccuu cgccagcugc ugcaucgccg ccuacagacc cagcgagacc cugugcggcg      180

gcgagcuggu ggacacccug caguucgugu gcggcgacag aggcuucuac uucagcagac      240

ccgccagcag agugagcaga agaagcagag gcaucgugga ggagugcugc uucagaagcu      300

gcgaccuggc ccugcuggag accuacugcg ccacccccgc caagagcgag agagacguga      360

gcaccccccc caccgugcug cccgacaacu uccccagaua ccccgugggc aaguucuucc      420

aguacgacac cuggaagcag agcacccaga gacugagaag aggccugccc gcccugcuga      480

gagccagaag aggccacgug cuggccaagg agcuggaggc cuucagagag gccaagagac      540

acagaccccu gaucgcccug cccacccagg accccgccca cggcggcgcc ccccccgaga      600

uggccagcaa cagaaaguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  4248
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt4)

<400>  4248
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagcuuca gcaccagcgc cuucggcccc guggccuuca      120

gccugggccu gcugcuggug cugcccgccg ccuuccccgc ccccgugccc cccggcgagg      180

acagcaagga cguggccgcc ccccacagac agccccugac cagcagcgag agaaucgaca      240

agcagaucag auacauccug gacggcauca gcgcccugag aaaggagacc ugcaacaaga      300

gcaacaugug cgagagcagc aaggaggccc uggccgagaa caaccugaac cugcccaaga      360

uggccgagaa ggacggcugc uuccagagcg gcuucaacga ggagaccugc cuggugaaga      420

ucaucaccgg ccugcuggag uucgaggugu accuggagua ccugcagaac agauucgaga      480

gcagcgagga gcaggccaga gccgugcaga ugagcaccaa ggugcugauc caguuccugc      540

agaagaaggc caagaaccug gacgccauca ccacccccga ccccaccacc aacgccagcc      600

ugcugaccaa gcugcaggcc cagaaccagu ggcugcagga caugaccacc caccugaucc      660

ugagaagcuu caaggaguuc cugcagagca gccugagagc ccugagacag augugaggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  4249
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt4)

<400>  4249
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcugu ggcugagagg cuuccugcug gccagcugcu      120

ggaucaucgu gagaagcagc cccacccccg gcagcgaggg ccacagcgcc gcccccgacu      180

gccccagcug cgcccuggcc gcccugccca aggacgugcc caacagccag cccgagaugg      240

uggaggccgu gaagaagcac auccugaaca ugcugcaccu gaagaagaga cccgacguga      300

cccagcccgu gcccaaggcc gcccugcuga acgccaucag aaagcugcac gugggcaagg      360

ugggcgagaa cggcuacgug gagaucgagg acgacaucgg cagaagagcc gagaugaacg      420

agcugaugga gcagaccagc gagaucauca ccuucgccga gagcggcacc gccagaaaga      480

cccugcacuu cgagaucagc aaggagggca gcgaccugag cgugguggag agagccgagg      540

uguggcuguu ccugaaggug cccaaggcca acagaaccag aaccaaggug accaucagac      600

uguuccagca gcagaagcac ccccagggca gccuggacac cggcgaggag gccgaggagg      660

ugggccugaa gggcgagaga agcgagcugc ugcugagcga gaagguggug gacgccagaa      720

agagcaccug gcacguguuc cccgugagca gcagcaucca gagacugcug gaccagggca      780

agagcagccu ggacgugaga aucgccugcg agcagugcca ggagagcggc gccagccugg      840

ugcugcuggg caagaagaag aagaaggagg aggagggcga gggcaagaag aagggcggcg      900

gcgagggcgg cgccggcgcc gacgaggaga aggagcagag ccacagaccc uuccugaugc      960

ugcaggccag acagagcgag gaccaccccc acagaagaag aagaagaggc cuggagugcg     1020

acggcaaggu gaacaucugc ugcaagaagc aguucuucgu gagcuucaag gacaucggcu     1080

ggaacgacug gaucaucgcc cccagcggcu accacgccaa cuacugcgag ggcgagugcc     1140

ccagccacau cgccggcacc agcggcagca gccugagcuu ccacagcacc gugaucaacc     1200

acuacagaau gagaggccac agccccuucg ccaaccugaa gagcugcugc gugcccacca     1260

agcugagacc caugagcaug cuguacuacg acgacggcca gaacaucauc aagaaggaca     1320

uccagaacau gaucguggag gagugcggcu gcagcugagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  4250
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt4)

<400>  4250
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccugc ccggcagagc ccugggcgcc gccugccugc      120

ugcugcuggc cgccggcugg cugggccccg aggccugggg cagccccacc ccccccccca      180

cccccgccgc cccccccccc cccccccccc ccggcagccc cggcggcagc caggacaccu      240

gcaccagcug cggcggcuuc agaagacccg aggagcuggg cagaguggac ggcgacuucc      300

uggaggccgu gaagagacac auccugagca gacugcagau gagaggcaga cccaacauca      360

cccacgccgu gcccaaggcc gccaugguga ccgcccugag aaagcugcac gccggcaagg      420

ugagagagga cggcagagug gagauccccc accuggacgg ccacgccagc cccggcgccg      480

acggccagga gagagugagc gagaucauca gcuucgccga gaccgacggc cuggccagca      540

gcagagugag acuguacuuc uucaucagca acgagggcaa ccagaaccug uucguggugc      600

aggccagccu guggcuguac cugaagcugc ugcccuacgu gcuggagaag ggcagcagaa      660

gaaaggugag agugaaggug uacuuccagg agcagggcca cggcgacaga uggaacaugg      720

uggagaagag aguggaccug aagagaagcg gcuggcacac cuucccccug accgaggcca      780

uccaggcccu guucgagaga ggcgagagaa gacugaaccu ggacgugcag ugcgacagcu      840

gccaggagcu ggccguggug cccguguucg uggaccccgg cgaggagagc cacagacccu      900

ucgugguggu gcaggccaga cugggcgaca gcagacacag aaucagaaag agaggccugg      960

agugcgacgg cagaaccaac cugugcugca gacagcaguu cuucaucgac uucagacuga     1020

ucggcuggaa cgacuggauc aucgccccca ccggcuacua cggcaacuac ugcgagggca     1080

gcugccccgc cuaccuggcc ggcgugcccg gcagcgccag cagcuuccac accgccgugg     1140

ugaaccagua cagaaugaga ggccugaacc ccggcaccgu gaacagcugc ugcaucccca     1200

ccaagcugag caccaugagc augcuguacu ucgacgacga guacaacauc gugaagagag     1260

acgugcccaa caugaucgug gaggagugcg gcugcgccug aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  4251
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt4)

<400>  4251
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagag ugcugcugcu gaccgcccug acccugugcc      120

acggcuucaa ccuggacacc gagaacgcca ugaccuucca ggagaacgcc agaggcuucg      180

gccagagcgu ggugcagcug cagggcagca gagugguggu gggcgccccc caggagaucg      240

uggccgccaa ccagagaggc agccuguacc agugcgacua cagcaccggc agcugcgagc      300

ccaucagacu gcaggugccc guggaggccg ugaacaugag ccugggccug agccuggccg      360

ccaccaccag ccccccccag cugcuggccu gcggccccac cgugcaccag accugcagcg      420

agaacaccua cgugaagggc cugugcuucc uguucggcag caaccugaga cagcagcccc      480

agaaguuccc cgaggcccug agaggcugcc cccaggagga cagcgacauc gccuuccuga      540

ucgacggcag cggcagcauc aucccccacg acuucagaag aaugaaggag uucgugagca      600

ccgugaugga gcagcugaag aagagcaaga cccuguucag ccugaugcag uacagcgagg      660

aguucagaau ccacuucacc uucaaggagu uccagaacaa ccccaacccc agaagccugg      720

ugaagcccau cacccagcug cugggcagaa cccacaccgc caccggcauc agaaaggugg      780

ugagagagcu guucaacauc accaacggcg ccagaaagaa cgccuucaag auccuggugg      840

ugaucaccga cggcgagaag uucggcgacc cccugggcua cgaggacgug auccccgagg      900

ccgacagaga gggcgugauc agauacguga ucggcguggg cgacgccuuc agaagcgaga      960

agagcagaca ggagcugaac accaucgcca gcaagccccc cagagaccac guguuccagg     1020

ugaacaacuu cgaggcccug aagaccaucc agaaccagcu gagagagaag aucuucgcca     1080

ucgagggcac ccagaccggc agcagcagca gcuucgagca cgagaugagc caggagggcu     1140

ucagcgccgc caucaccagc aacggccccc ugcugagcac cgugggcagc uacgacuggg     1200

ccggcggcgu guuccuguac accagcaagg agaagagcac cuucaucaac augaccagag     1260

uggacagcga caugaacgac gccuaccugg gcuacgccgc cgccaucauc cugagaaaca     1320

gagugcagag ccuggugcug ggcgccccca gauaccagca caucggccug guggccaugu     1380

ucagacagaa caccggcaug ugggagagca acgccaacgu gaagggcacc cagaucggcg     1440

ccuacuucgg cgccagccug ugcagcgugg acguggacag caacggcagc accgaccugg     1500

ugcugaucgg cgccccccac uacuacgagc agaccagagg cggccaggug agcgugugcc     1560

cccugcccag aggcagagcc agauggcagu gcgacgccgu gcuguacggc gagcagggcc     1620

agcccugggg cagauucggc gccgcccuga ccgugcuggg cgacgugaac ggcgacaagc     1680

ugaccgacgu ggccaucggc gcccccggcg aggaggacaa cagaggcgcc guguaccugu     1740

uccacggcac cagcggcagc ggcaucagcc ccagccacag ccagagaauc gccggcagca     1800

agcugagccc cagacugcag uacuucggcc agagccugag cggcggccag gaccugacca     1860

uggacggccu gguggaccug accgugggcg cccagggcca cgugcugcug cugagaagcc     1920

agcccgugcu gagagugaag gccaucaugg aguucaaccc cagagaggug gccagaaacg     1980

uguucgagug caacgaccag guggugaagg gcaaggaggc cggcgaggug agagugugcc     2040

ugcacgugca gaagagcacc agagacagac ugagagaggg ccagauccag agcgugguga     2100

ccuacgaccu ggcccuggac agcggcagac cccacagcag agccguguuc aacgagacca     2160

agaacagcac cagaagacag acccaggugc ugggccugac ccagaccugc gagacccuga     2220

agcugcagcu gcccaacugc aucgaggacc ccgugagccc caucgugcug agacugaacu     2280

ucagccuggu gggcaccccc cugagcgccu ucggcaaccu gagacccgug cuggccgagg     2340

acgcccagag acuguucacc gcccuguucc ccuucgagaa gaacugcggc aacgacaaca     2400

ucugccagga cgaccugagc aucaccuuca gcuucaugag ccuggacugc cugguggugg     2460

gcggccccag agaguucaac gugaccguga ccgugagaaa cgacggcgag gacagcuaca     2520

gaacccaggu gaccuucuuc uucccccugg accugagcua cagaaaggug agcacccugc     2580

agaaccagag aagccagaga agcuggagac uggccugcga gagcgccagc agcaccgagg     2640

ugagcggcgc ccugaagagc accagcugca gcaucaacca ccccaucuuc cccgagaaca     2700

gcgaggugac cuucaacauc accuucgacg uggacagcaa ggccagccug ggcaacaagc     2760

ugcugcugaa ggccaacgug accagcgaga acaacaugcc cagaaccaac aagaccgagu     2820

uccagcugga gcugcccgug aaguacgccg uguacauggu ggugaccagc cacggcguga     2880

gcaccaagua ccugaacuuc accgccagcg agaacaccag cagagugaug cagcaccagu     2940

accaggugag caaccugggc cagagaagcc ugcccaucag ccugguguuc cuggugcccg     3000

ugagacugaa ccagaccgug aucugggaca gaccccaggu gaccuucagc gagaaccuga     3060

gcagcaccug ccacaccaag gagagacugc ccagccacag cgacuuccug gccgagcuga     3120

gaaaggcccc cguggugaac ugcagcaucg ccgugugcca gagaauccag ugcgacaucc     3180

ccuucuucgg cauccaggag gaguucaacg ccacccugaa gggcaaccug agcuucgacu     3240

gguacaucaa gaccagccac aaccaccugc ugaucgugag caccgccgag auccuguuca     3300

acgacagcgu guucacccug cugcccggcc agggcgccuu cgugagaagc cagaccgaga     3360

ccaaggugga gcccuucgag gugcccaacc cccugccccu gaucgugggc agcagcgugg     3420

gcggccugcu gcugcuggcc cugaucaccg ccgcccugua caagcugggc uucuucaaga     3480

gacaguacaa ggacaugaug agcgagggcg gcccccccgg cgccgagccc cagugaggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  4252
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt4)

<400>  4252
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucagccuga agacccugcc cuuccugcug cugcugcacg      120

ugcagaucag caaggccuuc cccgugagca gcaaggagaa gaacaccaag accgugcagg      180

acuaccugga gaaguucuac cagcugccca gcaaccagua ccagagcacc agaaagaacg      240

gcaccaacgu gaucguggag aagcugaagg agaugcagag auucuucggc cugaacguga      300

ccggcaagcc caacgaggag acccuggaca ugaugaagaa gcccagaugc ggcgugcccg      360

acagcggcgg cuucaugcug acccccggca accccaagug ggagagaacc aaccugaccu      420

acagaaucag aaacuacacc ccccagcuga gcgaggccga gguggagaga gccaucaagg      480

acgccuucga gcuguggagc guggccagcc cccugaucuu caccagaauc agccagggcg      540

aggccgacau caacaucgcc uucuaccaga gagaccacgg cgacaacagc cccuucgacg      600

gccccaacgg cauccuggcc cacgccuucc agcccggcca gggcaucggc ggcgacgccc      660

acuucgacgc cgaggagacc uggaccaaca ccagcgccaa cuacaaccug uuccuggugg      720

ccgcccacga guucggccac agccugggcc uggcccacag cagcgacccc ggcgcccuga      780

uguaccccaa cuacgccuuc agagagacca gcaacuacag ccugccccag gacgacaucg      840

acggcaucca ggccaucuac ggccugagca gcaaccccau ccagcccacc ggccccagca      900

cccccaagcc cugcgacccc agccugaccu ucgacgccau caccacccug agaggcgaga      960

uccuguucuu caaggacaga uacuucugga gaagacaccc ccagcugcag agaguggaga     1020

ugaacuucau cagccuguuc uggcccagcc ugcccaccgg cauccaggcc gccuacgagg     1080

acuucgacag agaccugauc uuccuguuca agggcaacca guacugggcc cugagcggcu     1140

acgacauccu gcagggcuac cccaaggaca ucagcaacua cggcuucccc agcagcgugc     1200

aggccaucga cgccgccgug uucuacagaa gcaagaccua cuucuucgug aacgaccagu     1260

ucuggagaua cgacaaccag agacaguuca uggagcccgg cuaccccaag agcaucagcg     1320

gcgccuuccc cggcaucgag agcaaggugg acgccguguu ccagcaggag cacuucuucc     1380

acguguucag cggccccaga uacuacgccu ucgaccugau cgcccagaga gugaccagag     1440

uggccagagg caacaagugg cugaacugca gauacggcug aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  4253
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt4)

<400>  4253
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguggc agccccuggu gcuggugcug cuggugcugg      120

gcugcugcuu cgccgccccc agacagagac agagcacccu ggugcuguuc cccggcgacc      180

ugagaaccaa ccugaccgac agacagcugg ccgaggagua ccuguacaga uacggcuaca      240

ccagaguggc cgagaugaga ggcgagagca agagccuggg ccccgcccug cugcugcugc      300

agaagcagcu gagccugccc gagaccggcg agcuggacag cgccacccug aaggccauga      360

gaacccccag augcggcgug cccgaccugg gcagauucca gaccuucgag ggcgaccuga      420

aguggcacca ccacaacauc accuacugga uccagaacua cagcgaggac cugcccagag      480

ccgugaucga cgacgccuuc gccagagccu ucgcccugug gagcgccgug accccccuga      540

ccuucaccag aguguacagc agagacgccg acaucgugau ccaguucggc guggccgagc      600

acggcgacgg cuaccccuuc gacggcaagg acggccugcu ggcccacgcc uucccccccg      660

gccccggcau ccagggcgac gcccacuucg acgacgacga gcuguggagc cugggcaagg      720

gcgugguggu gcccaccaga uucggcaacg ccgacggcgc cgccugccac uuccccuuca      780

ucuucgaggg cagaagcuac agcgccugca ccaccgacgg cagaagcgac ggccugcccu      840

ggugcagcac caccgccaac uacgacaccg acgacagauu cggcuucugc cccagcgaga      900

gacuguacac ccaggacggc aacgccgacg gcaagcccug ccaguucccc uucaucuucc      960

agggccagag cuacagcgcc ugcaccaccg acggcagaag cgacggcuac agauggugcg     1020

ccaccaccgc caacuacgac agagacaagc uguucggcuu cugccccacc agagccgaca     1080

gcaccgugau gggcggcaac agcgccggcg agcugugcgu guuccccuuc accuuccugg     1140

gcaaggagua cagcaccugc accagcgagg gcagaggcga cggcagacug uggugcgcca     1200

ccaccagcaa cuucgacagc gacaagaagu ggggcuucug ccccgaccag ggcuacagcc     1260

uguuccuggu ggccgcccac gaguucggcc acgcccuggg ccuggaccac agcagcgugc     1320

ccgaggcccu gauguacccc auguacagau ucaccgaggg ccccccccug cacaaggacg     1380

acgugaacgg caucagacac cuguacggcc ccagacccga gcccgagccc agacccccca     1440

ccaccaccac cccccagccc accgcccccc ccaccgugug ccccaccggc ccccccaccg     1500

ugcaccccag cgagagaccc accgccggcc ccaccggccc ccccagcgcc ggccccaccg     1560

gcccccccac cgccggcccc agcaccgcca ccaccgugcc ccugagcccc guggacgacg     1620

ccugcaacgu gaacaucuuc gacgccaucg ccgagaucgg caaccagcug uaccuguuca     1680

aggacggcaa guacuggaga uucagcgagg gcagaggcag cagaccccag ggccccuucc     1740

ugaucgccga caaguggccc gcccugccca gaaagcugga cagcguguuc gaggagagac     1800

ugagcaagaa gcuguucuuc uucagcggca gacaggugug gguguacacc ggcgccagcg     1860

ugcugggccc cagaagacug gacaagcugg gccugggcgc cgacguggcc caggugaccg     1920

gcgcccugag aagcggcaga ggcaagaugc ugcuguucag cggcagaaga cuguggagau     1980

ucgacgugaa ggcccagaug guggacccca gaagcgccag cgagguggac agaauguucc     2040

ccggcgugcc ccuggacacc cacgacgugu uccaguacag agagaaggcc uacuucugcc     2100

aggacagauu cuacuggaga gugagcagca gaagcgagcu gaaccaggug gaccaggugg     2160

gcuacgugac cuacgacauc cugcagugcc ccgaggacug aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  4254
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt4)

<400>  4254
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg ugcuggccgc cuuccuguuc cugagcugga      120

cccacugcag agcccugccc cugcccagcg gcggcgacga ggacgaccug agcgaggagg      180

accugcaguu cgccgagaga uaccugagaa gcuacuacca ccccaccaac cuggccggca      240

uccugaagga gaacgccgcc agcagcauga ccgagagacu gagagagaug cagagcuucu      300

ucggccugga ggugaccggc aagcuggacg acaacacccu ggacgugaug aagaagccca      360

gaugcggcgu gcccgacgug ggcgaguaca acguguuccc cagaacccug aaguggagca      420

agaugaaccu gaccuacaga aucgugaacu acacccccga caugacccac agcgaggugg      480

agaaggccuu caagaaggcc uucaaggugu ggagcgacgu gaccccccug aacuucacca      540

gacugcacga cggcaucgcc gacaucauga ucagcuucgg caucaaggag cacggcgacu      600

ucuaccccuu cgacggcccc agcggccugc uggcccacgc cuuccccccc ggccccaacu      660

acggcggcga cgcccacuuc gacgacgacg agaccuggac cagcagcagc aagggcuaca      720

accuguuccu gguggccgcc cacgaguucg gccacagccu gggccuggac cacagcaagg      780

accccggcgc ccugauguuc cccaucuaca ccuacaccgg caagagccac uucaugcugc      840

ccgacgacga cgugcagggc auccagagcc uguacggccc cggcgacgag gaccccaacc      900

ccaagcaccc caagaccccc gacaagugcg accccagccu gagccuggac gccaucacca      960

gccugagagg cgagaccaug aucuucaagg acagauucuu cuggagacug cacccccagc     1020

agguggacgc cgagcuguuc cugaccaaga gcuucuggcc cgagcugccc aacagaaucg     1080

acgccgccua cgagcacccc agccacgacc ugaucuucau cuucagaggc agaaaguucu     1140

gggcccugaa cggcuacgac auccuggagg gcuaccccaa gaagaucagc gagcugggcc     1200

ugcccaagga ggugaagaag aucagcgccg ccgugcacuu cgaggacacc ggcaagaccc     1260

ugcuguucag cggcaaccag guguggagau acgacgacac caaccacauc auggacaagg     1320

acuaccccag acugaucgag gaggacuucc ccggcaucgg cgacaaggug gacgccgugu     1380

acgagaagaa cggcuacauc uacuucuuca acggccccau ccaguucgag uacagcaucu     1440

ggagcaacag aaucgugaga gugaugcccg ccaacagcau ccuguggugc ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4255
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt4)

<400>  4255
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acaccaccga ggacuacgac accaccaccg      120

aguucgacua cggcgacgcc acccccugcc agaaggugaa cgagagagcc uucggcgccc      180

agcugcugcc cccccuguac agccuggugu ucgugaucgg ccuggugggc aacauccugg      240

uggugcuggu gcuggugcag uacaagagac ugaagaacau gaccagcauc uaccugcuga      300

accuggccau cagcgaccug cuguuccugu ucacccugcc cuucuggauc gacuacaagc      360

ugaaggacga cuggguguuc ggcgacgcca ugugcaagau ccugagcggc uucuacuaca      420

ccggccugua cagcgagauc uucuucauca uccugcugac caucgacaga uaccuggcca      480

ucgugcacgc cguguucgcc cugagagcca gaaccgugac cuucggcgug aucaccagca      540

ucaucaucug ggcccuggcc auccuggcca gcaugcccgg ccuguacuuc agcaagaccc      600

agugggaguu cacccaccac accugcagcc ugcacuuccc ccacgagagc cugagagagu      660

ggaagcuguu ccaggcccug aagcugaacc uguucggccu ggugcugccc cugcugguga      720

ugaucaucug cuacaccggc aucaucaaga uccugcugag aagacccaac gagaagaaga      780

gcaaggccgu gagacugauc uucgugauca ugaucaucuu cuuccuguuc uggacccccu      840

acaaccugac cauccugauc agcguguucc aggacuuccu guucacccac gagugcgagc      900

agagcagaca ccuggaccug gccgugcagg ugaccgaggu gaucgccuac acccacugcu      960

gcgugaaccc cgugaucuac gccuucgugg gcgagagauu cagaaaguac cugagacagc     1020

uguuccacag aagaguggcc gugcaccugg ugaaguggcu gcccuuccug agcguggaca     1080

gacuggagag agugagcagc accagcccca gcaccggcga gcacgagcug agcgccggcu     1140

ucugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  4256
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt4)

<400>  4256
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agaacccugg ccugccugcu gcugcugggc ugcggcuacc      120

uggcccacgu gcuggccgag gaggccgaga uccccagaga ggugaucgag agacuggcca      180

gaagccagau ccacagcauc agagaccugc agagacugcu ggagaucgac agcgugggca      240

gcgaggacag ccuggacacc agccugagag cccacggcgu gcacgccacc aagcacgugc      300

ccgagaagag accccugccc aucagaagaa agagaagcau cgaggaggcc gugcccgccg      360

ugugcaagac cagaaccgug aucuacgaga uccccagaag ccagguggac cccaccagcg      420

ccaacuuccu gaucuggccc cccugcgugg aggugaagag augcaccggc ugcugcaaca      480

ccagcagcgu gaagugccag cccagcagag ugcaccacag aagcgugaag guggccaagg      540

uggaguacgu gagaaagaag cccaagcuga aggaggugca ggugagacug gaggagcacc      600

uggagugcgc cugcgccacc accagccuga accccgacua cagagaggag gacaccggca      660

gacccagaga gagcggcaag aagagaaaga gaaagagacu gaagcccacc ugaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  4257
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt4)

<400>  4257
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagaugcu gggcccuguu ccugagccug ugcugcuacc      120

ugagacuggu gagcgccgag ggcgacccca uccccgagga gcuguacgag augcugagcg      180

accacagcau cagaagcuuc gacgaccugc agagacugcu gcacggcgac cccggcgagg      240

aggacggcgc cgagcuggac cugaacauga ccagaagcca cagcggcggc gagcuggaga      300

gccuggccag aggcagaaga agccugggca gccugaccau cgccgagccc gccaugaucg      360

ccgagugcaa gaccagaacc gagguguucg agaucagcag aagacugauc gacagaacca      420

acgccaacuu ccuggugugg ccccccugcg uggaggugca gagaugcagc ggcugcugca      480

acaacagaaa cgugcagugc agacccaccc aggugcagcu gagacccgug caggugagaa      540

agaucgagau cgugagaaag aagcccaucu ucaagaaggc caccgugacc cuggaggacc      600

accuggccug caagugcgag accguggccg ccgccagacc cgugaccaga agccccggcg      660

gcagccagga gcagagagcc aagacccccc agaccagagu gaccaucaga accgugagag      720

ugagaagacc ccccaagggc aagcacagaa aguucaagca cacccacgac aagaccgccc      780

ugaaggagac ccugggcgcc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  4258
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt4)

<400>  4258
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguucg gccugcugcu gcugaccagc gcccuggccg      120

gccagagaca gggcacccag gccgagagca accugagcag caaguuccag uucagcagca      180

acaaggagca gaacggcgug caggaccccc agcacgagag aaucaucacc gugagcacca      240

acggcagcau ccacagcccc agauuccccc acaccuaccc cagaaacacc gugcuggugu      300

ggagacuggu ggccguggag gagaacgugu ggauccagcu gaccuucgac gagagauucg      360

gccuggagga ccccgaggac gacaucugca aguacgacuu cguggaggug gaggagccca      420

gcgacggcac cauccugggc agauggugcg gcagcggcac cgugcccggc aagcagauca      480

gcaagggcaa ccagaucaga aucagauucg ugagcgacga guacuucccc agcgagcccg      540

gcuucugcau ccacuacaac aucgugaugc cccaguucac cgaggccgug agccccagcg      600

ugcugccccc cagcgcccug ccccuggacc ugcugaacaa cgccaucacc gccuucagca      660

cccuggagga ccugaucaga uaccuggagc ccgagagaug gcagcuggac cuggaggacc      720

uguacagacc caccuggcag cugcugggca aggccuucgu guucggcaga aagagcagag      780

ugguggaccu gaaccugcug accgaggagg ugagacugua cagcugcacc cccagaaacu      840

ucagcgugag caucagagag gagcugaaga gaaccgacac caucuucugg cccggcugcc      900

ugcuggugaa gagaugcggc ggcaacugcg ccugcugccu gcacaacugc aacgagugcc      960

agugcgugcc cagcaaggug accaagaagu accacgaggu gcugcagcug agacccaaga     1020

ccggcgugag aggccugcac aagagccuga ccgacguggc ccuggagcac cacgaggagu     1080

gcgacugcgu gugcagaggc agcaccggcg gcugaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  4259
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt4)

<400>  4259
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagacuga ucuucgugua cacccugauc ugcgccaacu      120

ucugcagcug cagagacacc agcgccaccc cccagagcgc cagcaucaag gcccugagaa      180

acgccaaccu gagaagagac gaccuguaca gaagagacga gaccauccag gugaagggca      240

acggcuacgu gcagagcccc agauucccca acagcuaccc cagaaaccug cugcugaccu      300

ggagacugca cagccaggag aacaccagaa uccagcuggu guucgacaac caguucggcc      360

uggaggaggc cgagaacgac aucugcagau acgacuucgu ggagguggag gacaucagcg      420

agaccagcac caucaucaga ggcagauggu gcggccacaa ggaggugccc cccagaauca      480

agagcagaac caaccagauc aagaucaccu ucaagagcga cgacuacuuc guggccaagc      540

ccggcuucaa gaucuacuac agccugcugg aggacuucca gcccgccgcc gccagcgaga      600

ccaacuggga gagcgugacc agcagcauca gcggcgugag cuacaacagc cccagcguga      660

ccgaccccac ccugaucgcc gacgcccugg acaagaagau cgccgaguuc gacaccgugg      720

aggaccugcu gaaguacuuc aaccccgaga gcuggcagga ggaccuggag aacauguacc      780

uggacacccc cagauacaga ggcagaagcu accacgacag aaagagcaag guggaccugg      840

acagacugaa cgacgacgcc aagagauaca gcugcacccc cagaaacuac agcgugaaca      900

ucagagagga gcugaagcug gccaacgugg uguucuuccc cagaugccug cuggugcaga      960

gaugcggcgg caacugcggc ugcggcaccg ugaacuggag aagcugcacc ugcaacagcg     1020

gcaagaccgu gaagaaguac cacgaggugc ugcaguucga gcccggccac aucaagagaa     1080

gaggcagagc caagaccaug gcccuggugg acauccagcu ggaccaccac gagagaugcg     1140

acugcaucug cagcagcaga ccccccagau gaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  4260
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt4)

<400>  4260
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugacccaca gcaaguuccc cgccgccggc augagcagac      120

cccuggacac cagccugaga cugaagaccu ucagcagcaa gagcgaguac cagcuggugg      180

ugaacgccgu gagaaagcug caggagagcg gcuucuacug gagcgccgug accggcggcg      240

aggccaaccu gcugcugagc gccgagcccg ccggcaccuu ccugaucaga gacagcagcg      300

accagagaca cuucuucacc cugagcguga agacccagag cggcaccaag aaccugagaa      360

uccagugcga gggcggcagc uucagccugc agagcgaccc cagaagcacc cagcccgugc      420

ccagauucga cugcgugcug aagcuggugc accacuacau gccccccccc ggcgccccca      480

gcuuccccag cccccccacc gagcccagca gcgaggugcc cgagcagccc agcgcccagc      540

cccugcccgg cagccccccc agaagagccu acuacaucua cagcggcggc gagaagaucc      600

cccuggugcu gagcagaccc cugagcagca acguggccac ccugcagcac cugugcagaa      660

agaccgugaa cggccaccug gacagcuacg agaaggugac ccagcugccc ggccccauca      720

gagaguuccu ggaccaguac gacgcccccc ugugaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  4261
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt4)

<400>  4261
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugcccagcg ccggccagcu ggcccuguuc gcccugggca      120

ucgugcuggc cgccugccag gcccuggaga acagcaccag cccccugagc gccgaccccc      180

ccguggccgc cgccguggug agccacuuca acgacugccc cgacagccac acccaguucu      240

gcuuccacgg caccugcaga uuccuggugc aggaggacaa gcccgccugc gugugccaca      300

gcggcuacgu gggcgccaga ugcgagcacg ccgaccugcu ggccguggug gccgccagcc      360

agaagaagca ggccaucacc gcccuggugg uggugagcau cguggcccug gccgugcuga      420

ucaucaccug cgugcugauc cacugcugcc aggugagaaa gcacugcgag uggugcagag      480

cccugaucug cagacacgag aagcccagcg cccugcugaa gggcagaacc gccugcugcc      540

acagcgagac cgugguguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  4262
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt4)

<400>  4262
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccccagcg gccugagacu gcugccccug cugcugcccc      120

ugcuguggcu gcuggugcug acccccggca gacccgccgc cggccugagc accugcaaga      180

ccaucgacau ggagcuggug aagagaaaga gaaucgaggc caucagaggc cagauccuga      240

gcaagcugag acuggccagc ccccccagcc agggcgaggu gccccccggc ccccugcccg      300

aggccgugcu ggcccuguac aacagcacca gagacagagu ggccggcgag agcgccgagc      360

ccgagcccga gcccgaggcc gacuacuacg ccaaggaggu gaccagagug cugauggugg      420

agacccacaa cgagaucuac gacaaguuca agcagagcac ccacagcauc uacauguucu      480

ucaacaccag cgagcugaga gaggccgugc ccgagcccgu gcugcugagc agagccgagc      540

ugagacugcu gagacugaag cugaaggugg agcagcacgu ggagcuguac cagaaguaca      600

gcaacaacag cuggagauac cugagcaaca gacugcuggc ccccagcgac agccccgagu      660

ggcugagcuu cgacgugacc ggcgugguga gacaguggcu gagcagaggc ggcgagaucg      720

agggcuucag acugagcgcc cacugcagcu gcgacagcag agacaacacc cugcaggugg      780

acaucaacgg cuucaccacc ggcagaagag gcgaccuggc caccauccac ggcaugaaca      840

gacccuuccu gcugcugaug gccacccccc uggagagagc ccagcaccug cagagcagca      900

gacacagaag agcccuggac accaacuacu gcuucagcag caccgagaag aacugcugcg      960

ugagacagcu guacaucgac uucagaaagg accugggcug gaaguggauc cacgagccca     1020

agggcuacca cgccaacuuc ugccugggcc ccugccccua caucuggagc cuggacaccc     1080

aguacagcaa ggugcuggcc cuguacaacc agcacaaccc cggcgccagc gccgcccccu     1140

gcugcgugcc ccaggcccug gagccccugc ccaucgugua cuacgugggc agaaagccca     1200

agguggagca gcugagcaac augaucguga gaagcugcaa gugcagcuga ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  4263
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt4)

<400>  4263
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg ugcugagcgc cuuccugauc cugcaccugg      120

ugaccguggc ccugagccug agcaccugca gcacccugga cauggaccag uucaugagaa      180

agagaaucga ggccaucaga ggccagaucc ugagcaagcu gaagcugacc agcccccccg      240

aggacuaccc cgagcccgag gaggugcccc ccgaggugau cagcaucuac aacagcacca      300

gagaccugcu gcaggagaag gccagcagaa gagccgccgc cugcgagaga gagagaagcg      360

acgaggagua cuacgccaag gagguguaca agaucgacau gccccccuuc uuccccagcg      420

agaacgccau cccccccacc uucuacagac ccuacuucag aaucgugaga uucgacguga      480

gcgccaugga gaagaacgcc agcaaccugg ugaaggccga guucagagug uucagacugc      540

agaaccccaa ggccagagug cccgagcaga gaaucgagcu guaccagauc cugaagagca      600

aggaccugac cagccccacc cagagauaca ucgacagcaa gguggugaag accagagccg      660

agggcgagug gcugagcuuc gacgugaccg acgccgugca cgaguggcug caccacaagg      720

acagaaaccu gggcuucaag aucagccugc acugccccug cugcaccuuc gugcccagca      780

acaacuacau cauccccaac aagagcgagg agcuggaggc cagauucgcc ggcaucgacg      840

gcaccagcac cuacaccagc ggcgaccaga agaccaucaa gagcaccaga aagaagaaca      900

gcggcaagac cccccaccug cugcugaugc ugcugcccag cuacagacug gagagccagc      960

agaccaacag aagaaagaag agagcccugg acgccgccua cugcuucaga aacgugcagg     1020

acaacugcug ccugagaccc cuguacaucg acuucaagag agaccugggc uggaagugga     1080

uccacgagcc caagggcuac aacgccaacu ucugcgccgg cgccugcccc uaccugugga     1140

gcagcgacac ccagcacagc agagugcuga gccuguacaa caccaucaac cccgaggcca     1200

gcgccagccc cugcugcgug agccaggacc uggagccccu gaccauccug uacuacaucg     1260

gcaagacccc caagaucgag cagcugagca acaugaucgu gaagagcugc aagugcagcu     1320

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  4264
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt4)

<400>  4264
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacc ugcagagagc ccugguggug cuggcccugc      120

ugaacuucgc caccgugagc cugagccuga gcaccugcac cacccuggac uucggccaca      180

ucaagaagaa gagaguggag gccaucagag gccagauccu gagcaagcug agacugacca      240

gcccccccga gcccaccgug augacccacg ugcccuacca ggugcuggcc cuguacaaca      300

gcaccagaga gcugcuggag gagaugcacg gcgagagaga ggagggcugc acccaggaga      360

acaccgagag cgaguacuac gccaaggaga uccacaaguu cgacaugauc cagggccugg      420

ccgagcacaa cgagcuggcc gugugcccca agggcaucac cagcaaggug uucagauuca      480

acgugagcag cguggagaag aacagaacca accuguucag agccgaguuc agagugcuga      540

gagugcccaa ccccagcagc aagagaaacg agcagagaau cgagcuguuc cagauccuga      600

gacccgacga gcacaucgcc aagcagagau acaucggcgg caagaaccug cccaccagag      660

gcaccgccga guggcugagc uucgacguga ccgacaccgu gagagagugg cugcugagaa      720

gagagagcaa ccugggccug gagaucagca uccacugccc cugccacacc uuccagccca      780

acggcgacau ccuggagaac auccacgagg ugauggagau caaguucaag ggcguggaca      840

acgaggacga ccacggcaga ggcgaccugg gcagacugaa gaagcagaag gaccaccaca      900

acccccaccu gauccugaug augauccccc cccacagacu ggacaacccc ggccagggcg      960

gccagagaaa gaagagagcc cuggacacca acuacugcuu cagaaaccug gaggagaacu     1020

gcugcgugag accccuguac aucgacuuca gacaggaccu gggcuggaag ugggugcacg     1080

agcccaaggg cuacuacgcc aacuucugca gcggccccug ccccuaccug agaagcgccg     1140

acaccaccca cagcaccgug cugggccugu acaacacccu gaaccccgag gccagcgcca     1200

gccccugcug cgugccccag gaccuggagc cccugaccau ccuguacuac gugggcagaa     1260

cccccaaggu ggagcagcug agcaacaugg uggugaagag cugcaagugc agcugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4265
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt4)

<400>  4265
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccccgugg ccgugugggc cgcccuggcc gugggccugg      120

agcugugggc cgccgcccac gcccugcccg cccagguggc cuucaccccc uacgcccccg      180

agcccggcag caccugcaga cugagagagu acuacgacca gaccgcccag augugcugca      240

gcaagugcag ccccggccag cacgccaagg uguucugcac caagaccagc gacaccgugu      300

gcgacagcug cgaggacagc accuacaccc agcuguggaa cugggugccc gagugccuga      360

gcugcggcag cagaugcagc agcgaccagg uggagaccca ggccugcacc agagagcaga      420

acagaaucug caccugcaga cccggcuggu acugcgcccu gagcaagcag gagggcugca      480

gacugugcgc cccccugaga aagugcagac ccggcuucgg cguggccaga cccggcaccg      540

agaccagcga cguggugugc aagcccugcg cccccggcac cuucagcaac accaccagca      600

gcaccgacau cugcagaccc caccagaucu gcaacguggu ggccaucccc ggcaacgcca      660

gcauggacgc cgugugcacc agcaccagcc ccaccagaag cauggccccc ggcgccgugc      720

accugcccca gcccgugagc accagaagcc agcacaccca gcccaccccc gagcccagca      780

ccgcccccag caccagcuuc cugcugccca ugggccccag cccccccgcc gagggcagca      840

ccggcgacuu cgcccugccc gugggccuga ucgugggcgu gaccgcccug ggccugcuga      900

ucaucggcgu ggugaacugc gugaucauga cccaggugaa gaagaagccc cugugccugc      960

agagagaggc caaggugccc caccugcccg ccgacaaggc cagaggcacc cagggccccg     1020

agcagcagca ccugcugauc accgccccca gcagcagcag cagcagccug gagagcagcg     1080

ccagcgcccu ggacagaaga gcccccacca gaaaccagcc ccaggccccc ggcguggagg     1140

ccagcggcgc cggcgaggcc agagccagca ccggcagcag cgacagcagc cccggcggcc     1200

acggcaccca ggugaacgug accugcaucg ugaacgugug cagcagcagc gaccacagca     1260

gccagugcag cagccaggcc agcagcacca ugggcgacac cgacagcagc cccagcgaga     1320

gccccaagga cgagcaggug cccuucagca aggaggagug cgccuucaga agccagcugg     1380

agacccccga gacccugcug ggcagcaccg aggagaagcc ccugccccug ggcgugcccg     1440

acgccggcau gaagcccagc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  4266
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt4)

<400>  4266
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgugauga gacuguuccc cugcuuccug cagcugcugg      120

ccggccuggc ccugcccgcc gugccccccc agcagugggc ccugagcgcc ggcaacggca      180

gcagcgaggu ggagguggug cccuuccagg aggugugggg cagaagcuac ugcagagccc      240

uggagagacu gguggacgug gugagcgagu accccagcga gguggagcac auguucagcc      300

ccagcugcgu gagccugcug agaugcaccg gcugcugcgg cgacgagaac cugcacugcg      360

ugcccgugga gaccgccaac gugaccaugc agcugcugaa gaucagaagc ggcgacagac      420

ccagcuacgu ggagcugacc uucagccagc acgugagaug cgagugcaga ccccugagag      480

agaagaugaa gcccgagaga agaagaccca agggcagagg caagagaaga agagagaagc      540

agagacccac cgacugccac cugugcggcg acgccgugcc cagaagauga ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  4267
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt4)

<400>  4267
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgacagac agaccgacac cgcccccagc cccagcuacc      120

accugcugcc cggcagaaga agaaccgugg acgccgccgc cagcagaggc cagggccccg      180

agcccgcccc cggcggcggc guggagggcg ugggcgccag aggcguggcc cugaagcugu      240

ucgugcagcu gcugggcugc agcagauucg gcggcgccgu ggugagagcc ggcgaggccg      300

agcccagcgg cgccgccaga agcgccagca gcggcagaga ggagccccag cccgaggagg      360

gcgaggagga ggaggagaag gaggaggaga gaggccccca guggagacug ggcgccagaa      420

agcccggcag cuggaccggc gaggccgccg ugugcgccga cagcgccccc gccgccagag      480

ccccccaggc ccuggccaga gccagcggca gaggcggcag aguggccaga agaggcgccg      540

aggagagcgg ccccccccac agccccagca gaagaggcag cgccagcaga gccggccccg      600

gcagagccag cgagaccaug aacuuccugc ugagcugggu gcacuggagc cuggcccugc      660

ugcuguaccu gcaccacgcc aaguggagcc aggccgcccc cauggccgag ggcggcggcc      720

agaaccacca cgagguggug aaguucaugg acguguacca gagaagcuac ugccacccca      780

ucgagacccu gguggacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      840

ccagcugcgu gccccugaug agaugcggcg gcugcugcaa cgacgagggc cuggagugcg      900

ugcccaccga ggagagcaac aucaccaugc agaucaugag aaucaagccc caccagggcc      960

agcacaucgg cgagaugagc uuccugcagc acaacaagug cgagugcaga cccaagaagg     1020

acagagccag acaggagaag aagagcguga gaggcaaggg caagggccag aagagaaaga     1080

gaaagaagag cagauacaag agcuggagcg uguacguggg cgccagaugc ugccugaugc     1140

ccuggagccu gcccggcccc caccccugcg gccccugcag cgagagaaga aagcaccugu     1200

ucgugcagga cccccagacc ugcaagugca gcugcaagaa caccgacagc agaugcaagg     1260

ccagacagcu ggagcugaac gagagaaccu gcagaugcga caagcccaga agaugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4268
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt4)

<400>  4268
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ugagcugggu gcacuggagc cuggcccugc      120

ugcuguaccu gcaccacgcc aaguggagcc aggccgcccc cauggccgag ggcggcggcc      180

agaaccacca cgagguggug aaguucaugg acguguacca gagaagcuac ugccacccca      240

ucgagacccu gguggacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      300

ccagcugcgu gccccugaug agaugcggcg gcugcugcaa cgacgagggc cuggagugcg      360

ugcccaccga ggagagcaac aucaccaugc agaucaugag aaucaagccc caccagggcc      420

agcacaucgg cgagaugagc uuccugcagc acaacaagug cgagugcaga cccaagaagg      480

acagagccag acaggagaag aagagcguga gaggcaaggg caagggccag aagagaaaga      540

gaaagaagag cagauacaag agcuggagcg uguacguggg cgccagaugc ugccugaugc      600

ccuggagccu gcccggcccc caccccugcg gccccugcag cgagagaaga aagcaccugu      660

ucgugcagga cccccagacc ugcaagugca gcugcaagaa caccgacagc agaugcaagg      720

ccagacagcu ggagcugaac gagagaaccu gcagaugcga caagcccaga agaugaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  4269
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt4)

<400>  4269
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcccccugc ugagaagacu gcugcuggcc gcccugcugc      120

agcuggcccc cgcccaggcc cccgugagcc agcccgacgc ccccggccac cagagaaagg      180

uggugagcug gaucgacgug uacaccagag ccaccugcca gcccagagag gugguggugc      240

cccugaccgu ggagcugaug ggcaccgugg ccaagcagcu ggugcccagc ugcgugaccg      300

ugcagagaug cggcggcugc ugccccgacg acggccugga gugcgugccc accggccagc      360

accaggugag aaugcagauc cugaugauca gauaccccag cagccagcug ggcgagauga      420

gccuggagga gcacagccag ugcgagugca gacccaagaa gaaggacagc gccgugaagc      480

ccgacagagc cgccaccccc caccacagac cccagcccag aagcgugccc ggcugggaca      540

gcgcccccgg cgcccccagc cccgccgaca ucacccaccc cacccccgcc cccggcccca      600

gcgcccacgc cgcccccagc accaccagcg cccugacccc cggccccgcc gccgccgccg      660

ccgacgccgc cgccagcagc guggccaagg gcggcgccug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  4270
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt4)

<400>  4270
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccugcugg gcuucuucag cguggccugc agccugcugg      120

ccgccgcccu gcugcccggc cccagagagg cccccgccgc cgccgccgcc uucgagagcg      180

gccuggaccu gagcgacgcc gagcccgacg ccggcgaggc caccgccuac gccagcaagg      240

accuggagga gcagcugaga agcgugagca gcguggacga gcugaugacc gugcuguacc      300

ccgaguacug gaagauguac aagugccagc ugagaaaggg cggcuggcag cacaacagag      360

agcaggccaa ccugaacagc agaaccgagg agaccaucaa guucgccgcc gcccacuaca      420

acaccgagau ccugaagagc aucgacaacg aguggagaaa gacccagugc augcccagag      480

aggugugcau cgacgugggc aaggaguucg gcguggccac caacaccuuc uucaagcccc      540

ccugcgugag cguguacaga ugcggcggcu gcugcaacag cgagggccug cagugcauga      600

acaccagcac cagcuaccug agcaagaccc uguucgagau caccgugccc cugagccagg      660

gccccaagcc cgugaccauc agcuucgcca accacaccag cugcagaugc augagcaagc      720

uggacgugua cagacaggug cacagcauca ucagaagaag ccugcccgcc acccugcccc      780

agugccaggc cgccaacaag accugcccca ccaacuacau guggaacaac cacaucugca      840

gaugccuggc ccaggaggac uucauguuca gcagcgacgc cggcgacgac agcaccgacg      900

gcuuccacga caucugcggc cccaacaagg agcuggacga ggagaccugc cagugcgugu      960

gcagagccgg ccugagaccc gccagcugcg gcccccacaa ggagcuggac agaaacagcu     1020

gccagugcgu gugcaagaac aagcuguucc ccagccagug cggcgccaac agagaguucg     1080

acgagaacac cugccagugc gugugcaaga gaaccugccc cagaaaccag ccccugaacc     1140

ccggcaagug cgccugcgag ugcaccgaga gcccccagaa gugccugcug aagggcaaga     1200

aguuccacca ccagaccugc agcugcuaca gaagacccug caccaacaga cagaaggccu     1260

gcgagcccgg cuucagcuac agcgaggagg ugugcagaug cgugcccagc uacuggaaga     1320

gaccccagau gagcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  4271
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt4)

<400>  4271
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagagu gggugguggu gaacguguuc augaugcugu      120

acgugcagcu ggugcagggc agcagcaacg agcacggccc cgugaagaga agcagccaga      180

gcacccugga gagaagcgag cagcagauca gagccgccag cagccuggag gagcugcuga      240

gaaucaccca cagcgaggac uggaagcugu ggagaugcag acugagacug aagagcuuca      300

ccagcaugga cagcagaagc gccagccaca gaagcaccag auucgccgcc accuucuacg      360

acaucgagac ccugaaggug aucgacgagg aguggcagag aacccagugc agccccagag      420

agaccugcgu ggagguggcc agcgagcugg gcaagagcac caacaccuuc uucaagcccc      480

ccugcgugaa cguguucaga ugcggcggcu gcugcaacga ggagagccug aucugcauga      540

acaccagcac cagcuacauc agcaagcagc uguucgagau cagcgugccc cugaccagcg      600

ugcccgagcu ggugcccgug aagguggcca accacaccgg cugcaagugc cugcccaccg      660

cccccagaca ccccuacagc aucaucagaa gaagcaucca gauccccgag gaggacagau      720

gcagccacag caagaagcug ugccccaucg acaugcugug ggacagcaac aagugcaagu      780

gcgugcugca ggaggagaac ccccuggccg gcaccgagga ccacagccac cugcaggagc      840

ccgcccugug cggcccccac augauguucg acgaggacag augcgagugc gugugcaaga      900

cccccugccc caaggaccug auccagcacc ccaagaacug cagcugcuuc gagugcaagg      960

agagccugga gaccugcugc cagaagcaca agcuguucca ccccgacacc ugcagcugcg     1020

aggacagaug ccccuuccac accagacccu gcgccagcgg caagaccgcc ugcgccaagc     1080

acugcagauu ccccaaggag aagagagccg cccagggccc ccacagcaga aagaaccccu     1140

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  4272
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt5)

<400>  4272
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgaug agaccggcuu cgaacacucc gggcuguggg      120

ugucuguccu cgccggacug cuucugggcg cuugccaggc ccaucccauc ccugacagcu      180

ccccgcuccu gcaauuuggg ggacagguua gacagcggua ccuuuauaca gaugacgcgc      240

agcaaacgga ggcucaccug gaaauucgcg aggauggcac cgugggcgga gccgccgacc      300

agucucccga aagccuccug cagcugaagg cucucaaacc uggcgugauc cagauucugg      360

gcgucaagac auccagauuc cuuugucaac ggcccgaugg ggcccuguac ggaucucucc      420

auuuugaccc ugaggcuugc agcuuccgcg agcugcuucu ggaagauggc uauaacgugu      480

accaguccga ggcccacggg cucccccugc aucugccugg aaauaaaagc ccgcacagag      540

accccgcgcc ucggggcccc gcccgcuuuc ucccucugcc cgggcuuccg ccugcucugc      600

ccgaaccucc cggaauccuc gcuccccagc cuccggaugu ugggucuucc gacccccuga      660

gcaugguggg cccuucucag gggagauccc ccagcuaugc cucuugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  4273
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt5)

<400>  4273
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc ccccucugcu ccugcuucug uucuggggcg      120

uggucuccca uucuuucccg gccacccucg agacacagga acaagacguu gaucuggugc      180

agaaguaccu ugagaaauau uacaaccuga agaaugacgg gagacaggug gaaaaacggc      240

gcaacagcgg acccgucgug gagaagcuca aacagaugca agaauuuuuc ggccugaagg      300

uuacggggaa gccugaugcu gagacccuga aagugaugaa gcagcccaga ugcggagucc      360

cugacguggc ccaguuuguu cucacagagg gcaauccccg gugggaacag acccaccuga      420

cauaucgcau cgagaacuac accccugauc uuccgagagc ggacguggau caugcuauug      480

aaaaagccuu ccaacugugg uccaauguca caccccucac cuuuacgaag gugucugagg      540

ggcaggccga caucaugauu agcuucgugc ggggagauca ccgcgacaac uccccuuuug      600

auggccccgg cgggaaucug gcucaugccu uccagccugg acccggcauc gggggagacg      660

cucacuuuga ugaggacgaa agauggacca acaauuuccg ggaguauaac cuucaccgcg      720

ucgccgcgca ugaacugggc cacucucucg ggcugagcca uuccacagac auuggagccc      780

ugauguaccc gagcuauacc uuuucuggcg auguucagcu cgcucaagac gauaucgacg      840

gcauccaggc cauuuacggg agaucccaga auccugugca acccaucgga ccucagacac      900

ccaaggcuug ugauagcaaa cugaccuucg acgccauuac gacaauccgg ggcgagguga      960

uguucuuuaa ggaucgcuuc uacaugagaa ccaaccccuu uuauccugaa gucgagcuua     1020

auuucauuuc uguguuuugg ccgcagcugc ccaacgggcu cgaggcggcc uacgaguucg     1080

cugaccggga ugaaguucgc uuuuucaaag gaaauaagua uugggccgug cagggccaaa     1140

acguccugca cggguacccu aaagacaucu auuccagcuu uggauucccc agaacaguga     1200

agcacauuga ugcugcccuu ucugaagaga acaccggcaa aaccuacuuu uucguugcca     1260

auaaguauug gcgguacgac gaauacaaaa gauccaugga cccuggcuau cccaagauga     1320

ucgcucauga uuuuccgggg aucggacaca agguggacgc ggucuucaug aaagauggcu     1380

ucuuuuacuu cuuucauggg acacgccagu auaaguucga cccuaaaacg aagcggauuc     1440

ugacccucca gaaagccaac agcugguuua auugcagaaa gaacugagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  4274
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt5)

<400>  4274
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc ccccucugcu ccugcuucug uucuggggcg      120

uggucuccca uucuuucguu cucaccgagg ggaacccgag augggaacag acacaccuga      180

cguaccggau ugagaauuau acccccgacc uuccucgcgc cgauguggac caugcuauug      240

aaaaggccuu ucaacugugg agcaacguga caccccucac cuucacaaaa gucuccgagg      300

gacaggcgga uaucaugauu ucuuuuguga gaggcgacca ccgggauaau agcccuuucg      360

acgggcccgg aggcaaccug gcucaugccu uucagccugg gccgggaauc ggcggcgaug      420

cccacuucga cgaagaugag cgcuggacca auaacuuuag agaguacaau cugcaccggg      480

uugcugccca ugaacucggg cacucccugg gacuuucuca uagcacagac auuggcgcuc      540

ugauguaucc cuccuacacc uucagcgggg augugcagcu cgcccaagac gauaucgacg      600

gaauccaggc gauuuauggc cgcucucaga acccugucca gcccaucggg ccucaaacgc      660

ccaaggccug cgacuccaaa cugaccuuug augcuauuac aaccaucaga ggagagguga      720

uguucuuuaa ggaccgguuc uacaugcgca caaauccguu cuauccugaa guugagcuua      780

acuuuauuag cguguucugg ccccagcugc cuaauggccu cgaggccgcu uacgaauuug      840

ccgauagaga cgagguccgg uucuuuaaag gcaacaagua cugggcggug caggggcaga      900

augugcugca cggauauccc aaggauaucu acucuuccuu cggcuuuccc cgcaccguca      960

aacacauuga cgccgcucug agcgaagaga acacggggaa gacauauuuc uuuguugcca     1020

auaaauacug gagauaugau gaauacaagc ggucuaugga cccuggauau ccgaaaauga     1080

ucgcucauga uuuccccggc aucgggcaca agguggacgc cguguuuaug aaggauggau     1140

ucuuuuacuu cuuccauggc acccgccaau acaaauuuga cccuaagaca aaaagaaucc     1200

ucacccugca gaaggccaac uccugguuca acugucggaa aaauugagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  4275
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt5)

<400>  4275
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaaaaaca uccugaagau ucucauggac agcuacucca      120

aagagucuaa gauccagacc gugagacggg ucacaagcgu uucccugcuu gccguguauc      180

ugacgaugaa uaccucuagc cucgugcugg cuaaacccau ugaaaacaca aaugauaccu      240

ccaucaagaa cgucgagaaa cuucgcaaug ccccuaacga agaaaauucu aaaaaggugg      300

aagacagcaa aaacgauaag guugagcacg ugaaaaauau ugaggaagcg aaggucgagc      360

aaguggcucc ggaaguuaag uccaaaagca cacugagauc ugccuccauc gccaacacca      420

auagcgagaa guacgacuuc gaguaucuca acggccuguc uuacacagaa cugaccaauc      480

ucaucaaaaa cauuaagugg aaucagauca acgggcuguu uaacuauucc acgggaagcc      540

agaaauucuu uggcgauaag aaucgggugc aggcuauuau caacgcccuu caagagucug      600

ggcgcaccua cacagcuaau gacaugaaag gaauugaaac cuucacagag guccugagag      660

ccggcuuuua ucucggguac uacaacgaug gacuguccua ucuuaaugac cggaacuucc      720

aggauaagug cauccccgcg augauugcca uccagaagaa uccuaacuuu aaacugggca      780

ccgcugugca ggacgaagug aucacgagcc ucggcaagcu gauugggaau gccuccgcua      840

acgccgaggu cguuaauaac ugugugcccg ugcugaaaca auuccgcgag aaucucaacc      900

aguacgcgcc ugauuauguc aagggaacag ccgugaauga acugaucaaa ggcauugagu      960

uugacuucuc uggggcugcc uacgaaaagg auguuaagac caugcccugg uauggaaaaa     1020

ucgacccuuu uauuaacgag cuuaaggcuc ugggccucua cgggaacauc acaagcgcca     1080

ccgaaugggc cuccgacgug ggaaucuauu accugagcaa auucggccuu uacucuacca     1140

auagaaacga uauuguccag ucccuggaga aggcugugga cauguauaaa uacggcaaga     1200

ucgcguuugu ugccauggag cggauuacau gggauuauga cgggaucgga agcaauggca     1260

agaaagugga ucaugacaag uuccucgaug acgcugaaaa acacuaccug ccgaagacgu     1320

auaccuucga uaacgggaca uuuauuaucc gcgccggaga caaagucucu gaggaaaaga     1380

ucaagagacu guacugggcc agccgggagg ugaaauccca guuccaucgc gucgugggca     1440

augauaaggc ucucgaaguu gggaacgccg acgacgugcu gaccaugaaa auuuuuaauu     1500

cucccgagga guauaaguuc aacacaaaua ucaacggagu cagcaccgau aauggcggcc     1560

uuuacauuga accuagaggg acguuuuaca cauaugagcg gacaccccaa caguccaucu     1620

ucagccugga ggagcucuuu cgccacgagu acacccauua ucugcaggcg agauaccuug     1680

uggacggacu guggggccaa gggccuuucu augagaaaaa ccggcucacc ugguuugaug     1740

aaggaaccgc ugaguucuuu gccggcucua caagaacguc cgggguucug ccccgcaaga     1800

gcauucuggg cuaccucgcc aaagacaagg uggaucaccg guauucucug aagaaaaccc     1860

uuaauuccgg auacgacgau agcgacugga uguucuacaa cuauggcuuu gcugucgccc     1920

acuaccugua ugaaaaggau augccgacau ucaucaaaau gaauaaggcu auucucaaca     1980

ccgacgugaa auccuacgau gaaaucauca agaagcuguc ugacgaugcc aacaaaaaua     2040

cagaguauca gaaccauauu caggagcugg cggacaagua ccagggggcc ggaaucccuc     2100

uugugagcga cgauuaucuc aaagaccacg gcuacaagaa ggcuuccgaa guuuacucug     2160

agauuagcaa ggccgcuucc cugaccaaua cgagcgucac cgccgaaaag ucucaauauu     2220

ucaacacauu uacccugaga gggacauaca ccggagagac guccaaaggc gaguucaagg     2280

auugggacga aaugagcaaa aagcucgaug ggacacugga gucucuugcg aaaaauuccu     2340

ggagcggcua uaagacccug acagccuacu uuaccaacua ucgcgugacc ucugacaaua     2400

aggugcagua cgaugucgug uuccauggag uucucacaga caacgcugau aucagcaaua     2460

acaaagcccc cauugcuaag gugacgggcc cuuccaccgg ggccgucgga cggaauaucg     2520

aauuuagcgg caaagacucu aaggaugagg acgggaaaau cguguccuau gauugggacu     2580

ucggagacgg cgccacaagc agagggaaga acuccguuca cgcuuacaaa aaggcgggca     2640

ccuacaaugu gacacugaag gucaccgaug acaaaggagc cacggcuaca gaaucuuuua     2700

ccauugagau caagaacgaa gauaccacaa cccccauuac aaaagagaug gagcccaaug     2760

acgauaucaa ggaagccaac ggcccuauug uggagggggu uacggugaaa ggagaccuga     2820

acggcagcga ugacgccgau accuucuauu uugacgucaa ggaagauggg gacgugacaa     2880

ucgagcuucc guacuccgga ucuagcaauu ucaccuggcu cguguauaag gagggcgacg     2940

aucagaacca caucgcuucc gggauugaca aaaauaacuc uaaggucggc acauuuaaaa     3000

gcaccaaggg acgccauuac guuuucaucu auaaacacga uuccgccagc aauauuucuu     3060

acucccugaa caucaagggc cuggggaaug aaaagcucaa agagaaggaa aacaaugaca     3120

gcucugauaa agcgacggug auucccaacu uuaauaccac aaugcaggga ucccugcuug     3180

gcgacgauag ccgggacuau uacucuuucg aggugaagga agagggggag gucaacaucg     3240

aacuggauaa aaaggacgag uucggaguga ccuggacacu ccauccugaa uccaauauca     3300

acgauagaau uaccuacggc caaguugacg gcaauaaggu gagcaacaaa gucaagcugc     3360

gccccgggaa auauuaccug cuuguguaua aguacuccgg aagcggcaau uaugagcucc     3420

ggguuaacaa augaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  4276
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt5)

<400>  4276
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucuccu      120

cugccuacag cauugcuaac acaaauuccg agaaauauga cuuugaauac cuuaacggcc      180

ugucuuauac ggagcucacc aaucugauca agaacauuaa auggaaucag aucaacgggc      240

uuuucaauua cagcacagga ucccaaaagu uuuucggcga uaaaaacaga guccaggcca      300

uuaucaaugc gcugcaggaa ucugggcgga ccuauacagc uaacgacaug aagggaaucg      360

agaccuuuac agaaguucuc cgcgccggcu ucuaccuggg guauuacaau gauggacuga      420

gcuaccucaa cgacagaaau uuucaggaua agugcauucc cgccaugauc gcuauucaga      480

aaaacccuaa uuucaagcug ggcaccgccg ugcaagacga ggugaucacg ucccuuggca      540

aacugauugg gaacgcuagc gccaacgcgg aggucgugaa uaacuguguu ccggugcuca      600

agcaguuucg ggaaaaucug aaccaguaug cccccgauua cgucaaagga accgcuguga      660

augagcuuau caagggcauu gaguucgacu uuucuggggc cgcuuaugaa aaggauguua      720

aaacaaugcc uugguacgga aagaucgacc ccuucaucaa cgagcugaaa gcccucggcc      780

uguaugggaa uauuaccucc gcgacagaau gggccagcga ugugggaauc uacuaucugu      840

cuaaguucgg ccucuacucc accaaccgca augacauugu ccaaagccug gagaaagcug      900

uggauaugua caaguauggc aaaaucgccu uuguggcuau ggaaagaauu acgugggacu      960

acgacgggau cggaucuaac ggcaagaagg ucgaucacga caaauuccuu gaugacgccg     1020

agaagcauua ucugccuaaa acauacaccu uugauaaugg gacauucauc auucgggccg     1080

gagacaaggu uuccgaagag aaaaucaagc gccucuauug ggcuagcaga gaggugaagu     1140

cccaguuuca ccgggugguc ggcaacgaua aagcgcugga aguggggaau gccgacgaug     1200

uucuuaccau gaagauuuuc aacucucccg aggaauacaa auuuaauacc aacaucaacg     1260

gagugagcac agacaauggc ggccuguaua uugagccucg cgggacguuc uacaccuacg     1320

aaagaacacc gcagcagucc aucuuuagcc ucgaggagcu guuccggcau gaauauaccc     1380

acuaccugca agcucgcuau cucgucgaug gacugugggg ccaggggccc uuuuacgaga     1440

agaacagacu uacaugguuc gacgaaggaa ccgccgaguu uuucgccggc ucuacgcgga     1500

cauccggggu gcugccucgc aaaagcaucc ucggcuaucu ggcuaaggac aagguugauc     1560

auagauacuc ucuuaaaaag acccugaaua gcggauauga cgauuccgac uggauguucu     1620

acaacuacgg cuuugccgug gcgcacuauc ucuacgaaaa agauaugccc accuucauua     1680

agaugaauaa agcuauccug aacacagacg ucaagucuua ugaugagauu aucaagaaac     1740

ugagcgacga ugccaauaag aacaccgagu accagaauca cauucaagaa cucgccgaca     1800

aauaucaggg ggcuggaauc ccucuggugu ccgaugacua ccuuaaggau cauggcuaua     1860

aaaaggccag cgaggucuac ucugaaauuu ccaaagcugc cagccugaca aacacgucug     1920

ugaccgcgga gaagucccag uacuuuaaua cauucacccu ccgggggaca uauaccggag     1980

agacgagcaa gggcgaauuu aaagacuggg acgagauguc caagaaacug gaugggaccc     2040

uggaaucucu ugccaagaac agcugguccg gcuacaaaac acucaccgcu uauuucacaa     2100

auuacagagu uaccucugac aacaaggugc aguaugaugu cguguuucac ggaguucuga     2160

cggacaaugc cgauaucagc aacaacaagg cucccaucgc caaagugaca ggcccgucca     2220

ccggggcggu cggacgcaau auugaguuca gcggcaagga cucuaaagau gaagacggga     2280

agaucguguc cuacgauugg gacuuuggag auggcgccac aagccggggg aaaaacucug     2340

ugcaugcuua uaagaaggcc ggcaccuaca auguuacccu gaaagucaca gacgauaagg     2400

gagcuacggc caccgagucc uucacaauug agaucaaaaa cgaagacacc acaaccccua     2460

uuacgaagga gauggaaccc aaugacgaua ucaaagaggc caacggcccu aucguggaag     2520

gggugacagu caagggagac cucaauggca gcgaugacgc ugauaccuuu uacuucgacg     2580

ugaaggagga uggggacguu accauugagc ugcccuauuc uggaagcucc aacuuuacau     2640

ggcuugugua caaagaaggc gaugaccaaa aucacaucgc gagcgggauu gauaagaaca     2700

auucuaaagu cggcaccuuc aaguccacaa aaggaagaca cuauguguuc aucuacaagc     2760

augacagcgc cuccaacauu ucuuauagcc ugaauaucaa aggccucggg aacgagaagc     2820

ugaaggaaaa agagaauaac gacuccucug auaaggcuac gguuaucccc aacuuuaaua     2880

ccacaaugca gggaagccug cuuggcgacg auucccgcga cuacuauucu uucgaaguga     2940

aagaggaggg ggaagucaac auugagcucg auaagaaaga cgaauuugga gugaccugga     3000

cacugcaccc ugagagcaau aucaacgauc ggauuaccua cggccagguu gacggcaaua     3060

agguguccaa caaggucaaa cugagaccgg ggaaguacua ucuccuggug uacaaauaua     3120

gcggaucugg caauuacgag cuucgcguga acaagugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  4277
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt5)

<400>  4277
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucuccu      120

cugccuacag caugaaaaag aacauucuua aaauccugau ggacuccuau ucuaaggaga      180

gcaaaauuca gacagucaga cggguuacgu ccgugucucu ccuggcugug uaccuuacca      240

ugaauacaag cucccugguc cucgccaagc ccaucgaaaa caccaaugau acaagcauua      300

agaacgugga gaaacugcgc aaugcgccua acgaagaaaa uucuaagaaa guugaagacu      360

ccaagaacga uaaaguggag cacgucaaga auaucgagga agcuaaggug gagcaaguug      420

ccccggaagu gaaaagcaag ucuacccuga gauccgccag ccggcgcaga cggaaacgca      480

ucgcuaacac aaauucugag aaguaugacu uugaguaccu caacggccug uccuauaccg      540

aacuuacgaa ucugauuaaa aacaucaagu ggaaucagau uaacggacuc uucaacuaca      600

gcaccggauc ccagaaauuu uucggcgaua agaauagagu ccaggccauc auuaacgcuc      660

ugcaagaguc ugggcggaca uauaccgcca augacaugaa gggaaucgaa acauuuaccg      720

aggugcuucg cgcgggcuuc uaccuggggu acuauaacga uggacucagc uaccugaaug      780

acagaaacuu ucaggauaaa ugcauucccg ccaugaucgc uauccagaag aauccuaacu      840

ucaaacuggg cacggccgug caggacgaag ucauuacauc ccucggcaag cugaucggga      900

augcuagcgc caacgcggag guugugaaua acugugugcc cguccuuaaa caauuucggg      960

agaaucugaa ccaguaugcc ccugauuacg ugaagggaac cgcuguuaau gaacucauua     1020

agggcaucga guucgacuuu ucuggggccg cuuaugaaaa agaugugaag acaaugcccu     1080

gguacggaaa aauugacccu uucaucaacg agcugaaggc ccuuggccug uaugggaaca     1140

ucaccuccgc caccgaaugg gcuagcgacg ucggaauuua cuaccucucu aaauucggcc     1200

uguauagcac aaaucgcaac gauaucgugc agucccugga gaaggcgguu gacauguaca     1260

aguauggcaa aauugccuuu guggcuaugg agagaaucac gugggauuac gacgggauug     1320

gaucuaaugg caagaaaguc gaucaugaca aguuccucga ugacgccgaa aaacacuauc     1380

ugccgaagac cuacacauuu gauaacggga ccuucaucau ccgggccgga gacaagguga     1440

gcgaggaaaa gauuaagcgc cuuuauuggg cuuccagaga ggucaaaagc caguuucauc     1500

gggugguugg caaugauaag gcccuggaag uggggaacgc ggacgacguc cucacaauga     1560

aaaucuucaa uucucccgag gaguacaagu uuaacaccaa uauuaacgga guguccacgg     1620

auaauggcgg ccuguacauc gaaccuagag ggacauucua uaccuacgag cgcacacccc     1680

aacagagcau uuuuagccuu gaggagcugu uccggcacga guauacccau uaccuccagg     1740

cuagauaucu gguugacgga cuguggggcc aagggccuuu uuacgagaaa aaccgccuca     1800

ccugguucga ugaaggaaca gccgaauuuu ucgccggcuc cacgcggacc agcggggugc     1860

ugcccagaaa guccauccuu ggcuaucugg cuaaggacaa agucgaucac cgcuacucuc     1920

ucaagaaaac acugaauagc ggauacgacg auuccgacug gauguucuau aacuacggcu     1980

uugccguggc ucacuaucug uacgagaagg auaugccgac cuucauuaaa augaauaagg     2040

ccauccuuaa cacagacgug aagucuuaug augaaaucau uaaaaagcuc agcgacgaug     2100

cgaacaaaaa uaccgaguac cagaaccaua uccaggagcu ggccgacaag uaucaggggg     2160

cugggauucc ucugguuucc gacgauuacc ucaaagacca cggcuacaag aaggccagcg     2220

aagucuauuc ugagaucucc aaagcugcca gccugacgaa uaccucugug acagcggaaa     2280

agucccaaua cuuuaacacc uucacacuuc gggggaccua uacgggagag acaagcaaag     2340

gcgaauuuaa ggauugggac gagaugucua aaaagcugga ugggacccuc gagagccugg     2400

ccaaaaauuc cuggagcggc uacaaaacac ugaccgcuua uuucaccaac uacagaguga     2460

caucugacaa uaagguccag uaugaugugg uuuuucaugg agugcuuacg gacaacgccg     2520

auauuuccaa uaacaaagcu cccaucgcca aggucaccgg cccuagcaca ggggccgugg     2580

gacgcaauau cgaguucucc ggcaaagacu cuaaggauga agacgggaaa auuguuagcu     2640

acgauuggga cuuuggagac ggcgcuaccu cccgggggaa gaacucugug cacgcguaca     2700

agaaagccgg cacauauaau gucacccuca aggugacgga ugacaaagga gcuacagcca     2760

ccgaaucuuu caccaucgag auuaagaacg aagauacaac cacacccauc acgaaagaga     2820

uggagcccaa ugacgauauu aaggaagcca acggcccuau cguugagggg gugaccguca     2880

agggagaccu gaacggcucc gaugacgcug auacauuuua cuucgacgug aaagaagaug     2940

gggacgugac caucgagcug ccguauucug gaagcuccaa uuuuacaugg cucgucuaca     3000

aggagggcga cgaucagaac cacauugcca gcgggaucga caaaaauaac ucuaagguug     3060

gcaccuucaa auccacgaag ggaagacauu auguguucau uuacaagcac gauagcgcgu     3120

cuaauaucuc cuauagccug aacauuaaag gccuugggaa ugaaaagcug aaagagaagg     3180

aaaacaauga cucuuccgau aaagcuaccg ugauccccaa cuuuaauaca accaugcagg     3240

gaagccuccu gggcgacgau ucccgcgacu acuacagcuu cgaggucaag gaagaggggg     3300

aggugaacau cgaacuggau aagaaagacg aguuuggagu uacauggacc cuucauccug     3360

aaucuaauau uaacgaucgg aucacauaug gccaagugga cggcaauaag gucagcaaca     3420

aagugaagcu cagacccggg aaauacuauc ugcugguuua caaguauucc ggaucuggca     3480

auuacgagcu ccgggugaac aagugaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  4278
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt5)

<400>  4278
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuga agaucauucu caauagaggc aaaaccauga      120

agcggaaaug ccugagcaag cgccuuaugc uggccaucac aauggcuacg auuuuuaccg      180

ugaacuccac acuccccauc uacgccgcgg ucgacaaaaa uaacgcuacc gccgccguuc      240

agaaugaguc uaagagauau acagugagcu accugaagac ccuuaacuau uacgaucugg      300

uggaccuccu ggucaaaaca gaaauugaga aucugccuga ucucuuccaa uauuccucug      360

acgcuaagga auuuuacggg aacaaaaccc ggaugagcuu caucauggau gagaucggac      420

gcagagcccc gcaguauacg gaaauugacc acaagggcau ccccacccug guggagguug      480

ugcgggcugg guuuuaccuu ggauuccaua auaaagagcu gaacgaaauu aauaagcgcu      540

ccuuuaagga gagagucauc ccuucuauuc ucgccaucca gaaaaacccc aauuucaagc      600

ugggcacaga agugcaggau aaaauuguua gcgcgaccgg gcuucuggcc ggaaacgaga      660

cagcuccucc cgaggugguc aauaacuuua ccccuauccu ccaagacugu aucaagaaca      720

uugaucggua cgcccuggac gaucugaaau ccaaggcucu cuucaaugug cuggccgcgc      780

cgacguauga caucacagaa uaccuucgcg ccaccaaaga gaagcccgaa aacacaccuu      840

gguauggcaa gauugauggc uuuaucaaug agcugaaaaa gcucgcucug uacgggaaaa      900

uuaacgacaa uaacagcugg aucaucgaca auggaauuua ucacaucgcu ccccuuggca      960

agcugcauuc uaacaauaaa auugggaucg aaacccucac cgaggugaug aaggucuacc     1020

cuuaucuguc caugcagcac cuucagagcg ccgaucagau uaagagacau uacgacucua     1080

aagaugccga gggaaacaag aucccccucg acaaauucaa gaaagaaggc aaggagaagu     1140

acugcccgaa aacauauacg uuugaugacg ggaagguuau cauuaaagcc ggagcucggg     1200

uggaagagga aaaggugaaa cgccuguacu gggcguccaa ggaggucaau agccaauucu     1260

ucagagugua uggcaucgau aagccucuug aggaaggcaa ccccgacgau auucugacca     1320

ugguuaucua caauucuccu gaggaauaua aacucaacuc cgugcuguac ggguaugaca     1380

caaauaacgg aggcauguac auugagcccg aagggaccuu uuucacauac gagcgggagg     1440

cccaggaaag caccuauacg cuugaggaac uguuucgcca cgaguacaca cacuaucucc     1500

agggaagaua cgcugucccc ggccaguggg ggcggaccaa gcuguaugau aacgacagac     1560

ugaccuggua cgaggaagga ggcgccgaac ucuucgccgg cuccacacgc accucuggga     1620

uccugccucg gaaaagcauu guguccaaua uccauaacac aacgagaaau aaccgcuaua     1680

agcugagcga caccguucac ucuaaauacg gagcuuccuu ugaguucuac aauuaugccu     1740

guauguuuau ggauuacaug uauaacaagg acaugggcau ccugaauaaa cucaacgauc     1800

uggcgaagaa uaacgacgug gauggguacg acaauuauau ucgggaucug agcucuaacu     1860

acgcucuuaa ugacaaguau caagaucaua ugcaggagag aaucgacaac uacgaaaauc     1920

ucacaguccc guucguggcc gaugacuacc ugguccgcca cgccuauaaa aaccccaacg     1980

agauuuacag cgagaucucc gaaguggcua agcugaaaga ugccaagucu gagguuaaaa     2040

agagccagua uuuuuccacc uucacacucc ggggaagcua caccggcggg gcuucuaagg     2100

gcaaacugga agaccaaaag gccaugaaua aauuuauuga cgauucccuu aagaaacugg     2160

acacguauag cuggucugga uacaagaccc ucacagcgua uuucaccaac uacaaggugg     2220

auuccagcaa uagagucaca uacgacgugg uuuuucacgg cuaucugccu aacgaggggg     2280

auuccaaaaa uucucugccc uacggaaaga ucaacggcac cuauaaaggg acggaaaagg     2340

agaaaaucaa guucagcucc gagggaucuu ucgacccuga uggcaagauu gugagcuacg     2400

aaugggacuu uggggauggc aauaaaucca acgaggaaaa ucccgagcau agcuaugaca     2460

aggucggaac auacaccgug aaacuuaagg ugacagauga caaaggcgaa ucuuccguua     2520

gcaccaccac agccgagauc aaggaucucu cugagaacaa acugccgguc auuuauaugc     2580

acgugccuaa guccggggcu cugaaucaga agguggucuu cuacggaaaa ggcacguacg     2640

accccgacgg gagcaucgcc ggauaucagu gggauuuugg cgacgggucu gauuucagcu     2700

ccgaacagaa cccuagccau guguacacca agaaaggcga guauacaguu acccuccgcg     2760

ugauggacuc uuccggacaa augagcgaaa agacaaugaa aauuaagauc accgaucccg     2820

ucuacccuau cggcacggag aaggagccca auaacuccaa agaaacagcu ucugggccga     2880

uugugccugg aauccccguu agcggcacca uugagaauac cuccgaccag gauuauuuuu     2940

acuucgacgu gaucacaccc ggggaaguca agauugauau caacaaacug ggauauggcg     3000

gggccaccug ggugguuuac gacgagaaca auaacgcggu gucuuacgcc acagaugacg     3060

gccagaaucu uagcggaaag uuuaaagcug acaagccugg ccgguauuac auccaccugu     3120

auauguucaa cggguccuac augccguaua gaauuaauau cgaaggaucu gucggccgcu     3180

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  4279
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt5)

<400>  4279
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagagaaaau gccugagcaa gcggcucaug cuggccauca      120

ccauggcuac aauuuucacg gugaacucca cccuucccau cuacgccgcg gucgacaaaa      180

auaacgcuac agccgccguu cagaaugagu cuaagcgcua uaccgugagc uaccugaaaa      240

cacucaacua uuacgaucug guggaccuuc uggucaagac cgaaauugag aaucucccug      300

aucuguuuca auauuccucu gacgcuaagg aguucuacgg caacaaaaca agaaugagcu      360

uuaucaugga ugaaauuggg cggcgcgccc cgcaguauac cgaaaucgac cacaagggaa      420

uccccacgcu gguggagguu gugagagcug gcuucuaccu cggguuucau aauaaagagc      480

ugaacgaaau uaauaagcgg uccuucaaag agcgcgucau cccuucuauu cuugccaucc      540

agaagaaccc caauuuuaag cugggaaccg aagugcagga uaaaauuguu agcgcgacag      600

gccuccuggc cgggaacgag accgcuccuc ccgagguggu caauaacuuc acaccuaucc      660

uucaagacug uauuaagaau aucgauagau acgcccugga cgaucucaaa uccaaggcuc      720

uguuuaacgu gcuggccgcg ccgaccuaug acaucacgga auaccuccgg gccacaaaag      780

agaagcccga aaacaccccu ugguauggaa aaauugaugg cuucaucaau gagcugaaga      840

aacuugcucu guacggcaag auuaacgaca auaacagcug gaucauugac aaugggaucu      900

aucacaucgc uccccucgga aagcugcauu cuaacaauaa aauuggcauc gaaacacuua      960

ccgaggugau gaaggucuac ccuuaucugu ccaugcagca ccuccagagc gccgaucaga     1020

uuaaacgcca uuacgacucu aaggaugccg aggggaacaa gaucccccug gacaaauuua     1080

agaaagaagg aaaggagaaa uacugcccga agaccuauac auucgaugac ggcaagguua     1140

uuaucaaagc cggggcuaga guggaagagg aaaaggugaa acggcuguac ugggcgucca     1200

aggaggucaa uagccaauuu uuccgcgugu auggaaucga uaaaccucuc gaggaaggca     1260

accccgacga uauucugacg augguuaucu acaauucucc ugaggaauau aaacuuaacu     1320

ccgugcugua cggcuaugac accaauaacg ggggaaugua cauugagccc gaaggcacau     1380

ucuuuaccua cgagagagag gcccaggaaa gcacauauac ccucgaggaa cuguuccggc     1440

acgaguacac gcacuaucuu caggggcgcu acgcuguccc cggacagugg ggcagaacaa     1500

agcuguauga uaaugaccgg cucaccuggu acgaggaagg gggagccgag cuguuugccg     1560

gcuccaccag aacaucuggc auccugccuc gcaagagcau uguguccaac auccauaaca     1620

ccacacggaa uaacagauau aagcucagcg acacgguuca cucuaaauac ggggcuuccu     1680

ucgaauuuua caauuaugcc uguauguuca uggauuacau guauaacaag gacaugggca     1740

uucugaauaa acuuaacgau cuggcgaaga auaacgacgu ggauggauac gacaauuaua     1800

uccgcgaucu cagcucuaac uacgcucuga augacaaaua ucaagaucau augcaggagc     1860

ggaucgacaa cuacgaaaau cugaccgucc cguuuguggc cgaugacuac cuugucagac     1920

acgccuauaa gaaccccaau gagauuuaca gcgagaucuc cgaaguggcu aagcucaaag     1980

augccaaguc ugagguuaaa aagagccagu auuucuccac auuuacccug cgcgggagcu     2040

acacaggagg cgcuucuaaa gggaagcugg aagaccaaaa ggccaugaac aaauucauug     2100

acgauucccu caagaaacug gacaccuaua gcuggucugg cuacaagacg cuuaccgcgu     2160

auuuuacaaa cuacaaagug gauuccagca aucgggucac cuacgacgug guuuuccacg     2220

gauaucugcc uaacgagggc gauuccaaaa auucucuccc cuacgggaag aucaacggaa     2280

cauauaaggg caccgaaaag gagaaaauua aguuuagcuc cgaggggucu uucgacccug     2340

auggaaaaau cgugagcuac gaaugggacu ucggcgaugg gaauaagucc aacgaggaaa     2400

aucccgagca uagcuaugac aaggucggca cguacacagu gaaacugaag gugaccgaug     2460

acaaaggaga aucuuccguu agcacaacca ccgccgagau caaggaucug ucugagaaca     2520

aacuuccggu cauuuauaug cacgugccua aguccggcgc ucucaaucag aaaguggucu     2580

uuuacgggaa gggaacauac gaccccgacg gcagcaucgc cggguaucag ugggauuucg     2640

gagacggcuc ugauuuuagc uccgaacaga acccuagcca uguguacacg aagaaagggg     2700

aguauaccgu uacacugaga gugauggacu cuuccggcca aaugagcgaa aagaccauga     2760

aaauuaagau cacagauccc gucuacccua uuggaaccga gaaagagccc aauaacucca     2820

aggaaacggc uucuggcccg aucgugccug ggauccccgu uagcggaaca auugagaaua     2880

ccuccgacca ggauuauuuc uacuuugacg ugaucacccc cggcgaaguc aagauugaua     2940

ucaacaaacu gggguaugga ggcgccacau gggugguuua cgacgagaau aacaacgcgg     3000

ugucuuacgc caccgaugac gggcagaauc ucagcggcaa guucaaagcu gacaagccug     3060

gacgcuauua cauucaccug uauauguuua acggcuccua caugccguau cggaucaaua     3120

ucgaaggguc ugucggaaga ugaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  4280
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt5)

<400>  4280
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucuccu      120

cugccuacag cguccagaac gaguccaaaa gauauacagu uucuuaccuu aagacgcuga      180

auuauuacga ccucguggau cugcuuguga aaaccgaaau ugagaaccug cccgaccucu      240

uucaauauag cuccgaugcu aaggaguucu acggcaauaa aacacggaug ucuuuuauca      300

uggacgaaau ugggcgcaga gccccucagu auaccgaaau cgaucacaag ggcauuccga      360

cacuggucga ggugguucgg gcgggauucu accugggguu ucauaacaag gagcucaaug      420

aaaucaacaa acgcagcuuc aaggagagag ugauccccuc cauucuggcu auccagaaaa      480

auccuaacuu uaagcuggga accgaagucc aggacaaaau ugugagcgcc acaggccugc      540

ucgccgggaa ugagaccgcu cccccugagg uugugaacaa uuucacgccc auccugcaag      600

auugcauuaa gaacaucgac cgguacgccc uugaugaccu gaagucuaaa gcucucuuua      660

auguccuggc cgcgccuacc uaugauauua cagaauaccu gcgcgccacc aaggagaaac      720

cggaaaacac acccugguau ggaaagaucg acggcuucau caaugagcuc aaaaagcugg      780

cucuuuacgg caaaauuaac gauaacaauu ccuggaucau ugacaacggg aucuaucaca      840

uugccccucu gggaaagcuc cauagcaaua acaagaucgg caucgaaacc cugacggagg      900

ugaugaaagu guaccccuau cuuucuaugc agcaccuuca guccgcugac cagauuaaga      960

gacauuacga uagcaaagac gccgagggga auaagauccc ucucgauaaa uuuaagaagg     1020

aaggaaaaga gaaguacugu cccaaaacau auaccuucga cgauggcaag gucauuauca     1080

aagcgggggc ccggguugaa gaggaaaagg ugaagcgccu guacugggcu ucuaaagagg     1140

ugaacuccca auucuuuaga gucuauggaa uugacaagcc gcuggaggaa ggcaauccug     1200

augacauccu cacaauggug aucuacaaca gccccgagga auauaaacuu aauuccguuc     1260

uuuacggcua ugauaccaac aaugggggaa uguacauuga gccugaaggc accuucuuua     1320

cauacgagcg ggaggcccag gaaucuacgu auacccugga ggaacucuuc cgccacgagu     1380

acacacacua ucugcagggg agauacgcug ugcccggaca guggggccgg accaagcugu     1440

augacaacga ucgccugaca ugguacgagg aagggggagc cgagcucuuu gccggcagca     1500

ccagaacguc cggcauccug ccccggaaaa gcauugucuc uaauauccau aacacaacca     1560

gaaauaaccg cuauaagcug uccgacaccg ugcacagcaa guacggggcu ucuuucgaau     1620

uuuacaacua ugcgugcaug uucauggacu acauguauaa uaaagauaug ggcauucuca     1680

acaagcugaa ugaccuugcc aaaaacaaug auguugacgg auacgauaac uauauccggg     1740

accugagcuc caauuacgcu cucaacgaua aguaucaaga ccauaugcag gagagaauug     1800

auaauuacga aaaccugaca gugccuuuug ucgccgacga uuaccuggug cgccacgccu     1860

auaaaaaucc gaacgagauc uacucugaga ucagcgaagu cgcuaaacuu aaggacgcca     1920

aguccgaggu gaagaaaagc caguauuucu cuaccuuuac acuccggggg uccuacacgg     1980

gaggcgcgag caaggggaaa cuggaagauc aaaaggcuau gaauaaauuc auugacgacu     2040

cucugaagaa gcucgauacc uauuccugga gcggcuacaa aacacugacc gccuauuuua     2100

caaacuacaa gguugacucc ucuaauagag ugaccuacga ugucguguuc cacggauauc     2160

uucccaacga gggcgacagc aaaaacuccc ugccuuacgg gaagaucaau ggaacguaua     2220

aaggcaccga aaaggagaag auuaaauucu cuagcgaggg guccuuugau cccgacggaa     2280

agaucguuag cuacgaaugg gauuucggcg acgggaacaa aucuaaugag gaaaacccug     2340

agcauuccua ugauaaggug ggcacauaca ccgucaaacu caaggugaca gacgauaagg     2400

gagaaagcuc uguguccacc acgacagccg agauuaaaga ccugagcgag aauaagcugc     2460

ccguuaucua uaugcacguc ccgaaaucug gcgcucuuaa ccagaaggug guguuuuacg     2520

ggaaaggaac cuacgauccu gacggcagca ucgccgggua ucagugggac uucggagaug     2580

gcuccgacuu uagcucugaa cagaaucccu cccaugucua cacaaagaaa ggggaguaua     2640

ccgugacccu ccgcguuaug gauagcuccg gccaaauguc ugaaaagaca augaagauua     2700

aaaucacgga cccuguguac cccauuggaa ccgagaagga gccuaacaau agcaaagaaa     2760

cagcuuccgg ccccaucguc ccggggauuc cugugucugg aaccaucgag aacacaagcg     2820

aucaggacua uuucuacuuu gauguuauca cccccggcga agugaagauu gacaucaaua     2880

aacuggggua uggaggcgcc acgugggucg uguacgauga gaacaauaac gcgguuuccu     2940

acgccacaga cgaugggcag aaucugucug gcaaguucaa ggcugacaaa cccggacggu     3000

auuacauuca ccucuauaug uuuaacggca gcuacaugcc uuauagaauc aacauugaag     3060

gguccguggg acgcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4281
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt5)

<400>  4281
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucuccu      120

cugccuacag caugaaaaga aagugccuuu ccaaacggcu gaugcucgcu auuacaaugg      180

ccacgaucuu uaccgucaac ucuacacugc ccauuuaugc ggcuguugac aagaauaacg      240

ccaccgccgc ucgcagacgg cgcaaaagag ugcagaauga gagcaagcgg uacacagugu      300

ccuaucuuaa gacccugaac uacuaugauc ucgucgaccu gcuggugaaa acagaaaucg      360

agaaucuccc ugaucuguuc caauacucua gcgacgccaa ggaauuuuau ggcaacaaaa      420

cccgcauguc cuucauuaug gaugagaucg ggagacgggc uccgcaguac acggaaaucg      480

accacaaggg cauucccacc cuuguugagg ugguccgcgc cggauuuuac cugggguucc      540

auaauaaaga gcucaacgaa aucaauaaga gauccuuuaa ggagcgggug auuccuucua      600

uccuggcgau ucagaaaaac cccaauuuca aacuuggaac agaaguucag gauaagaucg      660

uguccgccac cggccugcuc gcugggaacg agacagcccc ucccgagguc gugaauaacu      720

uuaccccuau ucugcaagac uguaucaaga auaucgaucg cuaugcucug gacgaucuca      780

aaagcaaggc ccuguucaac gugcuugcgg ccccgacgua cgacauuaca gaauaucuga      840

gagcuaccaa agagaagccc gaaaacacac cuugguacgg aaagaucgau ggcuuuauua      900

augagcucaa aaagcuggcc cuuuauggca aaaucaacga caauaacucu uggauuaucg      960

acaaugggau cuaccacauu gcuccccugg gaaagcucca uuccaacaau aaaaucggca     1020

uugaaacccu gaccgagguc augaagguuu auccuuaccu gagcaugcag caccuccagu     1080

cugccgauca gaucaagcgg cauuacgacu ccaaagaugc cgaggggaac aagauucccc     1140

uggacaaauu caagaaagaa ggaaaggaga aguauugccc gaaaacauac acguucgaug     1200

acggcaaggu gaucaucaaa gcuggggcgc gcguggaaga ggaaaagguc aaaagacuuu     1260

auugggccag caaggaggug aauagccaau uuuuccgggu uuacggaauu gauaagccuc     1320

uggaggaagg caaccccgac gauauccuca ccauggugau uuauaauucu ccugaggaau     1380

acaaacugaa cagcguccuu uauggcuacg acacaaauaa cgggggaaug uacaucgagc     1440

ccgaaggcac cuuuuucaca uaugagagag aggcucagga auccaccuac acgcuggagg     1500

aacucuuucg ccacgaguau acacacuacc ugcaggggcg guaugccgug cccggacagu     1560

ggggcagaac caagcuguac gauaaugacc gccucaccug guaugaggaa gggggagccg     1620

agcuguucgc uggcagcaca cggaccucug gcauucuucc uagaaaaucc aucguuagca     1680

acauucauaa cacaacgcgc aauaaccggu acaagcuguc ugacaccgug cacagcaaau     1740

acggggccuc cuuugaguuc uauaauuacg cguguauguu uauggauuau auguacaaca     1800

aggacauggg aauccucaau aaacugaacg aucuggcuaa gaauaacgac gucgauggcu     1860

augacaauua caucagagau cuuucuagca acuaugcccu caaugacaag uaccaagauc     1920

auaugcagga acgcauugac aacuacgaaa aucugacagu gccguucguc gccgaugacu     1980

aucuggugcg gcacgcuuac aaaaacccca augagaucua uuccgagauu agcgaaguug     2040

ccaagcucaa agaugcuaag ucugagguga aaaaguccca guacuuuagc accuucacac     2100

ugagaggguc uuauaccgga ggcgccucca aggggaaacu ugaagaccaa aaggcgauga     2160

acaaauuuau cgacgauagc cugaagaaac ucgacacgua cuccuggucu ggcuauaaga     2220

cccugacagc cuacuucacc aacuacaagg ucgauagcuc caaucgcgug acauaugacg     2280

uuguguucca cggauaccug ccuaacgagg gcgauucuaa aaauagccuu cccuauggga     2340

agauuaacgg aaccuacaaa ggcacggaaa aggagaaaau caaguuuucc agcgaggggu     2400

cuuucgaccc ugauggaaag aucgucuccu augaauggga cuuuggcgau gggaauaaaa     2460

gcaacgagga aaaucccgag cauucuuacg acaagguggg cacauauacc gugaaacuca     2520

agguuacaga ugacaaagga gaauccagcg ucucuaccac cacagcugag auuaaggauc     2580

ugagcgagaa caaacugccg gugaucuaca ugcacgugcc uaaguccggc gcccucaauc     2640

agaaggucgu guucuacggg aaaggaacgu augaccccga cggcagcauu gcuggguacc     2700

agugggauuu uggagacggc ucugauuucu ccagcgaaca gaacccuucc cauguuuaua     2760

ccaagaaagg ggaguacaca gugacccugc gggucaugga cucuagcggc caaauguccg     2820

aaaagacaau gaaaaucaag auuaccgauc ccguguaucc uaucggaacg gagaaggagc     2880

ccaauaacuc uaaagaaaca gccagcggcc cgaucguucc ugggauuccc guguccggaa     2940

ccaucgagaa uaccucugac caggauuacu uuuauuucga cgucauuaca cccggcgaag     3000

ugaagaucga uauuaacaaa cuuggguacg gaggcgcgac cuggguugug uacgacgaga     3060

auaacaacgc cgucagcuau gcuacagaug acgggcagaa ucuguccggc aaguuuaaag     3120

ccgacaagcc uggaagauac uauauccacc ucuacauguu caacggcagc uauaugccgu     3180

accggaucaa uauugaaggg ucugugggac gcugaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  4282
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt5)

<400>  4282
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcugccu      120

uugcgaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc agcuaugagg      180

ugcugacacc ccucaagugg uaccagucca ucagaccucc cuauccuucu uacggguaug      240

aaccgauggg aggcuggcug caccaucaaa uuauccccgu ccuuagccag cagcacccuc      300

ccacgcauac ccugcagccu caccaccaua uucccguugu gccggcucaa cagccuguga      360

ucccccagca gccuaugaug cccguccccg ggcaacacuc caugacaccu auccagcauc      420

accagccgaa ucugcccccu cccgcccagc aaccuuacca gccccagccg gugcaaccuc      480

agccccacca gccuaugcag ccccaaccuc ccguucaucc gaugcagccu cucccucccc      540

agcccccgcu gcccccuaug uuucccaugc agccucugcc cccuaugcuc cccgaccuua      600

cccuggaggc cuggccgucu acagauaaaa ccaagcggga agagguggac ugaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  4283
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt5)

<400>  4283
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucacc ccucugaagu gguaccaguc cauuagaccu cccuaucccu      180

cuuacggaua ugaaccgaug ggcggguggu gaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  4284
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt5)

<400>  4284
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucaca ccccugaagu gguaccaguc cauuagaccu cccccuaugc      180

uuccggaccu gacccucgaa gccuggcccu cuacggauaa aaccaagcgg gaggaagucg      240

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  4285
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt5)

<400>  4285
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cugcuuagcg      120

gcgcccuggc gcucacacag acgugggcua ugccucugcc gccccacccu gggcaucccg      180

gauacaucaa cuucuccuau gagguucuua ccccucugaa gugguaccaa ucuauucggc      240

ccccuuaucc gagcuacggc uaugaaccca ugggagggug gugaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  4286
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt5)

<400>  4286
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cugcuuagcg      120

gcgcccuggc gcucacacag acgugggcua ugccucugcc gccccacccu gggcaucccg      180

gauacaucaa cuucuccuau gagguucuua ccccucugaa gugguaccaa ucuauucggc      240

ccccuccgau gcuccccgac cugacacugg aagccuggcc uagcaccgau aaaacaaagc      300

gcgaggaagu ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  4287
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt5)

<400>  4287
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccucgug ggggcugccu      120

uugcgaugcc ccugccuccg caccccggac auccuggcua cauuaacuuc agcuaugagg      180

uccuuacacc ccugaagugg uaccagucca ugaucagacc ucccuauucu agcuacgggu      240

augaaccuau gggaggcugg cuccaccauc aaauuauccc gguugugucc cagcagcacc      300

cccugacgca uacccuucag ucucaccacc auauuccugu gguccccgcu caacagccuc      360

gggugcgcca gcaggcccug augcccguuc cggggcaaca gagcaugaca ccuacccagc      420

accaucagcc caaucucccu cugcccgccc aacagcccuu ucagccucaa ccggugcagc      480

cccagccuca ccagcccaug caaccucagc ccccggucca gccuaugcag ccccugcucc      540

cucaaccccc ucugcccccg auguucccuc uuagaccccu gcccccuauc cucccggacc      600

ugcaccuuga ggcuuggccc gccacagaua aaaccaagca ggaagaggug gacugaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  4288
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt5)

<400>  4288
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucacc ccucugaagu gguaccaguc caugauuaga ccucccuauu      180

cuagcuacgg auaugaaccc augggcgggu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4289
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt5)

<400>  4289
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucaca ccccugaagu gguaccaguc caugauuaga ccucccccua      180

uccuuccgga ccugcaccuc gaagccuggc ccgcuaccga uaaaacgaag caagaggaag      240

ucgacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4290
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt5)

<400>  4290
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cugcuuagcg      120

gcgcccuggc gcucacacag acgugggcua ugccucugcc gccccacccu gggcaucccg      180

gauacaucaa cuucuccuau gagguucuua ccccucugaa gugguaccaa ucuaugauuc      240

ggcccccuua uagcuccuac ggcuaugaac cgaugggagg guggugagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4291
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt5)

<400>  4291
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cugcuuagcg      120

gcgcccuggc gcucacacag acgugggcua ugccucugcc gccccacccu gggcaucccg      180

gauacaucaa cuucuccuau gagguucuua ccccucugaa gugguaccaa ucuaugauuc      240

ggcccccucc gauccucccc gaccugcacc uggaagccug gccugccaca gauaaaacca      300

agcaggagga aguggacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4292
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt5)

<400>  4292
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcugccu      120

uuagcaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc uccuaugagg      180

ugcugacacc ccucaagugg uaccagaaua ugaucagaca cccuuauacg ucuuacgggu      240

augaacccau gggaggcugg cugcaucacc aaauuauccc ugucguuagc cagcagaccc      300

cgcaguccca ugcgcuucaa ccccaccacc auauuccuau ggugcccgcu cagcagccug      360

ggauccccca gcaaccgaug augccucugc ccggacagca cucuaugaca ccuacccagc      420

aucaccagcc caaccucccc cugccugccc aacagccguu ucagccccaa ccugugcagc      480

cccagccuca ccagccccug caaccgcaga gcccuaugca ucccauccag ccucuccugc      540

cccagccucc ccuuccgccu auguucucca ugcaaucucu gcuccccgac cugccccuug      600

aggccuggcc ugcuacagau aaaaccaagc gggaagaggu cgacugagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4293
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt5)

<400>  4293
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucaca ccccugaagu gguaccagaa uaugauuaga cacccuuaua      180

ccuccuacgg auaugaaccc augggcgggu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4294
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt5)

<400>  4294
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucaca ccccugaagu gguaccagaa uaugauuaga cacccuuccc      180

uucugcccga ccucccucug gaagccuggc cggcuaccga uaaaacgaag cgggaggaag      240

ucgacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4295
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt5)

<400>  4295
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cugcuuagcg      120

gcgcccuggc gcucacacag acgugggcua ugccucugcc gccccacccu gggcaucccg      180

gauacaucaa cuucuccuau gagguucuua ccccucugaa gugguaccaa aauaugauuc      240

ggcaccccua uacaucuuac ggcuaugaac cuaugggagg guggugagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4296
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt5)

<400>  4296
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cugcuuagcg      120

gcgcccuggc gcucacacag acgugggcua ugccucugcc gccccacccu gggcaucccg      180

gauacaucaa cuucuccuau gagguucuua ccccucugaa gugguaccaa aauaugauuc      240

ggcaccccuc ucuccugccu gaccugccgc ucgaagccug gcccgccaca gauaaaacca      300

agcgcgagga aguggacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4297
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt5)

<400>  4297
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcugccu      120

uuagcaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc uccuauauca      180

gacaccccua cacaucuuau ggguacgagc cuaugggagg cuggcugcau caccagauua      240

uccccguggu cagccaacag acgccucagu cccaugcgcu ccagccgcac caccauauuc      300

ccaugguucc ugcucaacag cccgggaucc cucagcagcc caugaugccg cugccuggac      360

aacacucuau gacccccaca cagcaucacc agccuaaucu uccccugccc gcccagcaac      420

cuuuucagcc gcagcccgug caaccucagc cccaccagcc ucuccagccc caaagcccga      480

ugcauccuau ccagccccug cugccucagc ccccucugcc cccgauguuc uccaugcagu      540

cucuccuucc ugaccugccc cucgaagccu ggcccgcuac cgauaagaca aaacgggagg      600

aaguggacug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  4298
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt5)

<400>  4298
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuuugc cugccugcuc ggggcuagcc      120

uggccaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc uccuaugagg      180

ugcugacacc ccucaagugg uaccagaaua ugaucagaca cccuuauacg ucuuacgggu      240

augaacccau gggaggcugg cugcaucacc aaauuauccc ugucguuagc cagcagaccc      300

cgcaguccca ugcgcuucaa ccccaccacc auauuccuau ggugcccgcu cagcagccug      360

ggauccccca gcaaccgaug augccucugc ccggacagca cucuaugaca ccuacccagc      420

aucaccagcc caaccucccc cugccugccc aacagccguu ucagccccaa ccugugcagc      480

cccagccuca ccagccccug caaccgcaga gcccuaugca ucccauccag ccucuccugc      540

cccagccucc ccuuccgccu auguucucca ugcaaucucu gcuccccgac cugccccuug      600

aggccuggcc ugcuacagau aaaaccaagc gggaagaggu cgacugagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4299
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt5)

<400>  4299
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcugccu      120

uuagcaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc uccuaugagg      180

ugcugacacc ccucaagugg uaccagaaua ugaucagaca cccuucucug cuucccgacc      240

ugccucucga agcguggccg gcuacggaua aaaccaagcg ggaggaaguc gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  4300
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt5)

<400>  4300
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcugccu      120

uuagcaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc uccuaugagg      180

accuguaccu cgaagcgauc agaauugauc ggacagcuuu ugugcugacg ccccuuaagu      240

gguaucagaa uaugauccgc cacccuuaca ccucuuaugg guacgagccc augggaggcu      300

ggcugcauca ccaaauuauc ccugucguua gccagcagac accgcagucc caugcccucc      360

aaccccacca ccauaucccu auggugcccg cccagcagcc ugggauuccc cagcaaccga      420

ugaugccucu gcccggacag cacucuauga ccccuacaca gcaucaccag cccaaccugc      480

cccucccugc ucaacagccg uuccagcccc aaccugugca gccccagccu caccagcccc      540

ugcaaccgca gagcccuaug caucccaucc agccucuucu gccccagccu ccccucccgc      600

cuauguuuuc caugcaaucu cugcuucccg accugccccu cgaagccugg ccugcuaccg      660

auaaaacaaa gagagaggaa gucgacugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  4301
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt5)

<400>  4301
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcugccu      120

uuagcaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc uccuaugagg      180

ugcugacacc ccucaagugg uaccagaaua ugaucagaca cccuacgccc caaucucaug      240

cgcugcagcc ucaccaucac auuccgaugg uccccgcuca gcagccuggg aucccccaac      300

agccuaugau gccccuuccg ggacagcaca gcaugacccc uacacagcau caccaaccca      360

accugccucu ccccgcccag cagcccuuuc agccucaacc gguucagccc cagccucauc      420

aaccccugca gccucagucc cccaugcacc cgauucagcc ucugcucccc caaccucccc      480

ugccucccau guucucuaug cagagccuuc ugccggaccu cccucuggaa gccuggcccg      540

cuaccgauaa aacaaagcgg gaggaagugg acugaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  4302
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt5)

<400>  4302
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucaca ccccugaagu gguaccagaa uaugauuaga cacccuuaua      180

ccuccuacgg auaugaaccc augggcgggu ggcuucauca ccaaaucauu ccugucguuu      240

cucagcagac gccgcagagc caugcccugc aaccccacca ccauaucccu auggugcccg      300

cucagcagcc uggcauuccc cagcaaccga ugaugccucu ccccggacag cacuccauga      360

ccccuacaca gcaucaccag cccaaccugc cccuuccugc ccaacagccg uuucagcccc      420

aaccugugca gccccagccu caccagcccc ugcaaccgca gucuccuaug caucccaucc      480

agccucuccu gccccagccu ccccugccgc cuauguucag caugcaaucc cuccugcccg      540

accuuccccu ggaggcgugg ccugcuaccg auaaaacaaa gcgggaagag gucgacugag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  4303
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt5)

<400>  4303
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg ccagacugcc ucuccugcuu gggcugcucc      120

ugcuuccgcg gcccggacgc ccucuggacc ucgcugauua caccuaugac cuggccgagg      180

aagaugacag cgagccccug aacuacaagg auccuugcaa agcggcugcc uuccucggcg      240

acaucgcccu ggaugaagag gaccuuagag cuuuucaggu ccaacaggcc guugaucugc      300

ggcgccacac agcuagaaag uccucuauua aagccgcggu gcccgggaau acgagcaccc      360

cuuccuguca gucuacaaac ggacagccgc aacggggcgc cugcgggcgc uggagaggac      420

ggagccgcuc cagacgggcu gccaccucuc gccccgaaag aguguggccu gacggcguca      480

uccccuucgu gauuggcggg aauuuuacag gaagccagcg ggcuguuuuc cgccaggcca      540

ugagacauug ggagaagcac accuguguga cauuucucga gcggaccgau gaagacuccu      600

auaucgucuu cacguacaga ccuugcggcu guugcagcua uguggggcgc cggggaggcg      660

ggccccaggc gauuucuauc ggaaagaacu gugauaaguu uggcaucguu gugcaugagc      720

ugggccacgu cgugggguuc uggcaugaac acaccagacc ggaccgcgac cggcacgugu      780

ccauugucag agagaauauc caaccuggac aggaguacaa cuuucuuaag auggaacccc      840

aggagguuga aagccugggc gagacauaug auuucgacuc uauuaugcau uacgcccgca      900

auaccuuuuc ccgggggauc uuccucgaua caauugugcc uaaauacgaa gugaacggag      960

ucaagccucc caucggccag agaacccgcc ugagcaaagg ggacauugcu caagcccgga     1020

agcuguauaa augccccgcu uguggagaga cgcuccagga uucuacaggc aauuuuucca     1080

gcccggagua ccccaacggc uauuccgccc acaugcauug cguguggaga aucucuguua     1140

ccccugggga aaagaucauu cugaauuuca caagccuuga ccuguaccgc ucccggcucu     1200

guugguauga uuacguggag gucagagacg gauucuggcg gaaggcuccc cugcgcggca     1260

gauuuugcgg gagcaaacuu ccugaaccca ucgugucuac cgauucccgg cuguggguug     1320

aguucagaag cucuagcaac ugggugggaa agggcuuuuu cgccgucuau gaagcgauuu     1380

gcgggggcga cgugaaaaag gauuacggac acauccaguc cccgaauuac ccugacgacu     1440

aucgccccuc uaaagucugu auuuggcgga uccaagugag cgagggcuuu cacguugggc     1500

ucaccuucca guccuuugag aucgaaagac augauagcug cgccuacgac uaucuggagg     1560

ugcgcgaugg acacucugaa uccagcacac ugauuggcag auacuguggg uaugagaagc     1620

cugacgauau caaaucuacg uccagccggc ucuggcugaa guucgucucc gacggaucua     1680

uuaacaaggc uggcuuugcc gugaauuucu uuaaagaagu ugaugagugc agccgcccca     1740

acagaggggg cugugagcag cggugccuua acacccuggg auccuacaag uguucuugcg     1800

acccuggcua ugaacucgcc cccgauaaac gcagauguga ggcugccugc gggggauucc     1860

ugacaaaacu uaauggcagc aucaccuccc cgggguggcc uaaagaauac ccucccaaca     1920

agaauuguau uuggcagcug guggcgccca cacaauaccg gaucagccuc caguuugacu     1980

ucuucgagac cgagggaaac gaugucugca aguaugacuu uguggaagug cgcucuggcc     2040

ugacggcuga uuccaaacug caugggaagu ucugcggcag cgagaaaccg gaaguuauca     2100

caucucagua caauaacaug agagucgagu uuaaguccga caauaccgug agcaaaaagg     2160

gauucaaggc ccacuuuuuc ucugacaaag augaauguag caaggacaac ggcgggugcc     2220

agcaagauug ugugaauacc uuuggauccu augagugcca gugucggagc ggcuucgucc     2280

uccaugacaa caaacacgau ugcaaggagg ccggguguga ccacaaagug acaucuaccu     2340

ccggaacaau uacgagcccc aauuggccug auaaguaccc cuccaagaaa gaaugcaccu     2400

gggcuaucuc uagcacaccu ggccaucgcg uuaagcugac cuuuauggag auggacauug     2460

aaucccagcc cgagugugcc uaugaucacc uugaaguguu cgacgggaga gaugcuaaag     2520

ccccuguccu gggccgguuu ugcggaucua agaaacccga gccggugcuc gcgacaggca     2580

gcagaauguu ccugcgcuuu uacuccgaca acucuguuca gcggaagggg uuccaagcca     2640

gccaugcuac cgagugugga ggccagguga gagccgaugu caaaacgaag gaccuguauu     2700

cccacgcuca guucggggac aauaacuacc cuggaggcgu ggauugcgaa uggguuaucg     2760

uggccgagga aggcuacggg gucgagcuug uguuucagac cuucgaagug gaggaggaaa     2820

cagacugcgg auaugauuac auggagcucu uugacggcua ugauagcacc gcgccccgcc     2880

uggggcggua cuguggaucu ggcccucccg aagaggucua uuccgccggg gacagcguuc     2940

uggugaaguu ccacucugau gacacaauua ccaaaaaggg auuucaucuc agauacacgu     3000

ccacaaaauu ccaagauacc cugcacagcc gcaagugagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  4304
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt5)

<400>  4304
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggca ccagaugccu gcucgcucug cuucugcccc      120

agguccuccu ugggggagcc gcgggccugg uuccugagcu ggggcggcgc aaguucgcug      180

ccgccagcuc cggaagaccg ucuagccaac ccuccgacga agugcucucu gaguuugaac      240

ugcggcugcu cagcauguuc ggccugaaac agcgcccuac acccuccaga gaugcugugg      300

ucccucccua caugcuugac cuguaucggc gccacucugg gcagccugga agcccggccc      360

ccgaucauag acucgagcgg gcugccuccc gcgcgaacac ggugagaucu uuucaccaug      420

aagagucucu ggaggaacuu ccugagaccu ccggcaagac aacccggcgc uucuuuuuca      480

aucugagcuc uauccccaca gaagaguuua uuaccuccgc cgagcuccag guuuucagag      540

aacaaaugca ggacgcucug ggcaacaaua gcucuuuuca ccaucggauc aacauuuacg      600

agaucauuaa accugccaca gcuaauucca aguuccccgu gacccgccug cucgauacga      660

gacuggucaa ccagaaugcc agccgguggg aauccuuuga cgugaccccg gcgguuauga      720

gauggacagc ccaggggcac gcuaaccacg gauucguggu cgagguggcc caucuugaag      780

agaaacaagg cgugucuaag cgccacgucc ggaucagcag aucccugcau caggaugagc      840

acagcugguc ucagauccgc ccucuccugg uuaccuuugg gcacgacgga aagggccauc      900

cccuucacaa acgggaaaag agacaggcua aacauaagca acgcaaacgg cugaagucca      960

gcuguaagag acacccucuc uauguggauu ucucugacgu gggguggaau gauuggauug     1020

ucgccccucc cggauaccau gccuucuauu gccacggcga gugucccuuu ccgcuggcug     1080

accaccugaa cagcacaaau caugcgaucg ugcagacccu cguuaacucc gugaauagca     1140

aaauucccaa ggccugcugu gucccuacgg aacugagcgc uaucuccaug cuuuaccugg     1200

augagaacga aaaagugguu cucaagaauu aucaggacau gguggucgag ggcugcgggu     1260

gucgcugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  4305
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt5)

<400>  4305
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auccccggca acagaaugcu gauggugguc cuccugugcc      120

agguucuucu cgggggagcc agccacgcuu cccugauucc ugagaccggc aagaaaaagg      180

uggccgaaau ccaagggcau gcgggaggcc ggcgcucugg gcagagccac gagcugcuua      240

gagacuucga agcuacacug cuccagaugu uuggacugcg gcgcagaccg cagcccucca      300

aaucugccgu gauuccugau uacaugcggg accuguaucg ccuccaaagc ggcgaggaag      360

aggaggaaca gauccauucc acgggccugg aguaccccga aagaccugcc ucucgggcua      420

auaccguccg cagcuuccac caugaggagc accuugaaaa cauucccggg acauccgaga      480

auagcgccuu uagauuccug uuuaaccucu cuuccauccc ugaaaaugag gugaucagcu      540

cugcugaacu gcggcuuuuc cgcgagcagg uugaucaggg accggacugg gagagaggcu      600

uucaccggau uaacaucuau gaagugauga agcccccugc cgaggucgug cccgggcauc      660

ugauuacccg ccuccuggau acaagacugg uucaccauaa ugugacccgg ugggaaacau      720

ucgacgucuc cccugcggug cucagaugga cccgcgagaa acaacccaac uacggacugg      780

ccaucgaagu gacgcaccuu caccagaccc ggacacauca gggccagcac gucagaauua      840

gccgcucucu gccgcaaggg uccggaaauu gggcucagcu ccggccucug cuuguuaccu      900

uuggccauga uggcagaggg cacgcccuga cacgccggag acgcgcuaag cggagcccca      960

agcaucacuc ccagagagcc cgcaaaaaga acaaaaauug ucggagacac ucucucuaug     1020

uggacuucag cgauguggga uggaacgacu ggaucgucgc gccucccggc uaccaagccu     1080

uuuauugcca uggggauugu cccuucccuc uggcugacca ccucaauucc accaaccaug     1140

ccauugugca gacgcugguu aauagcguga acucuuccau cccgaaggcu ugcugugucc     1200

ccacagagcu gagcgccauc ucuaugcuuu accuggauga guacgacaaa gugguucuca     1260

agaacuauca ggaaauggug gucgagggau gcggcugucg gugaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  4306
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt5)

<400>  4306
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggccugg ggagacgggc ccaguggcuc ugcugguggu      120

ggggacugcu uuguagcugc uguggcccuc cgccccugcg cccuccccuc ccugcugccg      180

cggcugccgc cgcuggggga caacugcuug gcgacggggg aucccccggc agaaccgagc      240

agccuccgcc cucuccucag agcuccucug gcuuccugua ccggcgccuc aagacacagg      300

agaaaagaga aaugcaaaag gaaauccuga gcgugcuggg gcucccccac cggccucgcc      360

cccugcaugg acuucagcag ccgcagccuc ccgcccugag acaacaggag gaacagcagc      420

aacagcagca acucccucgg ggcgagcccc cucccgggcg ccugaaaucc gcuccgcuuu      480

uuaugcugga ucucuauaac gcccugucug cggacaauga ugaggacgga gccagcgaag      540

gcgagagaca gcaguccugg ccccacgaag cugccuccuc uucccagcgg cgccaaccuc      600

ccccuggggc ugcccauccc cugaacagaa agagccuccu ggcgccggga ucuggcuccg      660

gcggggccag cccucuuacg ucugcucagg auuccgccuu ccugaaugac gcugauaugg      720

ucaugagcuu uguuaaccuc guggaguacg acaaagaguu cagcccccgg cagcgccacc      780

auaaggaauu uaaguucaau cugucucaga uuccugaggg agaagugguc accgccgccg      840

aguuuagaau cuauaaagau ugcgugaugg gcagcuucaa gaaccaaaca uuucuuauuu      900

ccaucuacca gguucugcag gaacaccagc accgggacag cgaucucuuc cugcuggaca      960

ccagaguggu cugggcuucu gaggaggggu ggcucgaauu ugauauuaca gcgaccucca     1020

aucugugggu gguuacaccc caacauaaca ugggacuuca gcugagcgug gucacccgcg     1080

acggcgugca cgugcauccu cgggccgcug ggcucgucgg aagagacggc cccuaugaua     1140

aacagccguu caugguugcc uuuuucaagg ugucugaggu gcacguccgc acgacccgga     1200

gcgccuccuc uagacgccgg cagcaaagca gaaaucgcuc cacacagagc caggacgugg     1260

cucggguuuc uuccgccagc gauuacaacu cuuccgaacu gaaaaccgcg uguagaaagc     1320

acgagcuuua ugugagcuuc caagaccugg gcuggcagga uuggaucauc gcuccuaagg     1380

gguacgccgc caauuacugc gacggagaau guuccuuucc ccucaacgcu cauaugaaug     1440

ccacaaacca cgcuauuguc cagacccugg ugcaucugau gaaucccgag uauguuccua     1500

aaccgugcug ugcccccacg aagcucaacg cgaucucugu gcuguacuuc gaugacaaca     1560

gcaaugucau ucuuaaaaag uaucgcaaca uggugguccg ggccugcggc ugucacugag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  4307
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt5)

<400>  4307
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugagaa gccugcgggc cgcugcuccc cauuccuucg      120

ucgcgcucug ggcuccucug uuucuucugc gcucugcccu cgccgacuuc agccuggaua      180

acgagguuca cuccucuuuu auccauagac ggcuucgcag ccaggaaaga cgggagaugc      240

aacgcgaaau ucuguccauc cucggccugc cgcacagacc ccggccucau cugcagggga      300

agcacaauuc ugcucccaug uucaugcucg accuguacaa cgccauggcu guggaggaag      360

gaggcgggcc uggaggccag ggguuuagcu aucccuacaa agccguguuc uccacccagg      420

gaccuccgcu ugcgagccug caagauucuc acuuucucac agacgccgau auggucaugu      480

ccuucgugaa ucugguugag caugacaagg aguuuuucca cccccgcuau caucacagag      540

aauuucgguu cgaucuuagc aaaauuccug agggcgaagc ugugacggcc gcugaguuuc      600

gcaucuacaa ggacuauauu agagagcggu ucgauaacga aaccuuccgc aucucugucu      660

accaggugcu gcaggagcac cucggcagag aauccgaccu guuucugcuc gauagccgga      720

cacugugggc cucugaggaa ggguggcuug uuuucgacau caccgcgaca uccaaucauu      780

ggguggucaa ccccagacac aaucugggac uccagcugag cguggagacc cuugauggcc      840

aauccauuaa cccuaaacug gccgggcuca ucggacgcca uggcccccag aauaagcagc      900

cguuuauggu ggcuuucuuu aaggccacag agguccacuu ccggucuauu agaagcaccg      960

gguccaaaca gcgcagccaa aaccggucua agacgccuaa aaaucaggaa gcucugagaa     1020

uggccaacgu ugccgaaaau uccagcucug accagcgcca agccugcaag aaacaugagc     1080

uguaugugag cuuucgggac cucggauggc aggauuggau cauugcgccc gagggcuacg     1140

ccgcuuacua uugugaaggc gagugcgccu ucccucugaa cuccuacaug aaugccacca     1200

accacgcuau cgugcagaca cuuguccacu uuauuaaccc cgagaccgug cccaagccuu     1260

guugcgcccc gacacagcug aaugcgaucu cuguucucua uuucgacgau agcuccaacg     1320

ugauccugaa gaaauacaga aauauggucg ugcgcgcuug ugggugccau ugaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  4308
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt5)

<400>  4308
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggccagcg cugcccugcu cugccugcuu cugaccgcgg      120

cugccuucuc uccccagggc cucgcccaac cuguggggau caacacaucc acgaccuguu      180

gcuacagauu uauuaauaaa aagaucccga aacagcggcu ggagagcuau cgcagaacaa      240

ccuccucuca cuguccccgg gaagcuguca uuuucaagac aaaacuugac aaggagaucu      300

gcgccgaucc uacccagaag uggguucagg acuuuaugaa acaucuggau aagaaaacac      360

aaacccccaa gcucugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  4309
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt5)

<400>  4309
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucaccc ugaucauucu ucugcccgug gucagcaagu      120

ucuccuuugu uucucucagc gccccucagc acugguccug cccggagggc acacuggcug      180

ggaacggaaa uucuacgugu gugggccccg ccccuuuccu uaucuuuagc caugggaacu      240

ccauuuucag aaucgacacc gaaggaacaa auuacgagca acuggugguc gaugcgggcg      300

ugucuguuau uauggacuuu cacuauaacg aaaaacggau cuacugggug gaucucgagc      360

gccagcugcu gcagagaguc uuccucaaug ggagccggca ggaacgcgug ugcaacaucg      420

agaagaaugu uuccggaaug gcuauuaacu ggaucaauga ggaagugauu uggagcaacc      480

aacaggaggg caucauuacc gucacagaca ugaaaggcaa uaacucucau auccugcuuu      540

ccgcccugaa guaucccgcc aauguggcug uggauccugu cgaaagauuu auuuucugga      600

gcucugaggu ugccgggucc cucuaccggg cugaccugga uggagugggc gugaaagccc      660

uucuggagac cagcgaaaag aucacagcgg ucucucucga cgugcuggau aagcgccugu      720

uuuggaucca guauaacaga gaggggucca auagccucau uuguuccugc gacuacgaug      780

gaggcucugu ucacaucagc aaacauccca cccagcacaa ccuguucgcc augucccuuu      840

uuggggaccg gauuuucuau agcacgugga agaugaaaac caucuggauu gcuaacaagc      900

acacaggaaa agauauggug cgcaucaauc ugcauucuuc cuuugucccu cucggcgaac      960

ugaagguggu ucacccgcuu gcccaaccca aggcugagga cgacaccugg gaaccugagc     1020

agaaacugug uaagcucaga aaaggcaacu gcagcucuac aguguguggg caggaucugc     1080

agagccaucu gugcaugugu gccgagggau acgcgcucuc ccgggaccgc aaguacugcg     1140

aagaugucaa ugagugugcc uucuggaacc acggcugcac ccuggggugc aaaaauacgc     1200

ccggaucuua uuacuguaca ugcccugugg gcuucguccu ucugcccgac gggaagagau     1260

gucaccaacu cgugagcugc ccgcggaacg uuuccgaaug uagccaugau ugcgugcuga     1320

ccucugaggg accucuuugu uuuugccccg aaggcuccgu ccuggagcgc gacggcaaaa     1380

cauguagcgg guguucuucc ccugauaaug gaggcugcag ccagcucugc gugccccugu     1440

cccccguuuc uugggagugc gacuguuucc cuggguauga ucugcagcuc gacgaaaaga     1500

gcugcgcugc cuccggaccg caacccuuuc ugcuuuucgc uaacucucag gauaucagac     1560

acaugcauuu ugacggcacc gacuacggga cccugcucag ccagcagaug ggcauggugu     1620

augcccugga ucacgacccu gucgagaaua agauuuacuu cgcccauaca gcucugaaau     1680

ggaucgaacg ggcgaacaug gauggauccc aaagagagcg ccuuauugaa gagggcgugg     1740

acgugcccga ggggcucgcc guugauugga ucggacggag auuuuauugg acggaccgcg     1800

gcaagagccu gauugggcgg ucugaucuga auggaaaaag auccaagauc aucaccaaag     1860

aaaacauuag ccagccucgc ggcaucgcug uccaccccau ggccaagcgg cuuuucugga     1920

cagacaccgg gauuaauccg agaaucgagu cuuccagccu gcagggccuu ggacgccugg     1980

ugauugccuc uagcgaucuc aucuggccuu ccggcauuac aaucgacuuu cugaccgaua     2040

agcuguacug gugugacgcu aaacagagcg ugaucgaaau ggccaaccuu gaugggucua     2100

agcggagacg ccucacgcaa aaugacgucg gacaccccuu cgcgguggcu guuuuugagg     2160

acuacgugug guucuccgau ugggccaugc cuagcgucau gcgggugaac aaaagaacag     2220

gcaaggaccg gguucgccug caggggucca ugcugaaacc cucuagccuc guggucgugc     2280

auccucuggc caagcccgga gcugauccgu gccuuuauca gaacggcggg ugugagcaca     2340

uuugcaagaa aagacugggc accgccuggu guuccugccg ggaaggauuu augaaggcuu     2400

cugacggcaa aaccugucuc gcccuggaug ggcaucagcu gcuugcggga ggcgagguug     2460

accucaagaa ucaagugaca ccucuggaua uccugagcaa aaccagaguc uccgaagaca     2520

acauuacaga gucucagcac augcucgugg ccgaaaucau ggugagcgau caggacgauu     2580

gcgcucccgu cggguguucc auguacgccc gcugcauuag cgagggagag gacgcuacgu     2640

gccagugucu gaagggcuuc gccggggaug gcaagcucug cucugacauc gacgaaugug     2700

agaugggagu ucccgugugc ccuccggcgu ccagcaaaug uaucaauacc gaaggcgggu     2760

augugugccg guguucugag ggauaccaag gcgaugggau ucacugccug gacaucgaug     2820

aaugucagcu cggagagcau uccugcggcg agaacgccag cuguacaaau accgaaggcg     2880

gguauacaug caugugcgcu ggaagacugu cugagcccgg ccugauuugu ccugacucca     2940

cgcccccucc ccaccuucgc gaagaugacc aucacuacag cgucagaaac uccgauagcg     3000

agugcccucu cucucaugac ggguauuguc ugcacgaugg agugugcaug uacaucgaag     3060

cccuggacaa guacgcuugu aauugcguug ugggcuauau uggggagcgg ugucaguacc     3120

gcgaucucaa auggugggag cugagacacg ccggacaugg ccaacagcag aaggucaucg     3180

ugguugccgu gugcgucgug guucuuguga ugcugcuccu gcugagccuu uggggcgcuc     3240

acuauuaccg gacccagaaa cugcucucca agaaccccaa aaauccguau gaagagucua     3300

gccgcgacgu cagaucccgg cgcccugcgg acaccgaaga ugggaugucu agcugucccc     3360

aaccuugguu cguggugauc aaggagcauc aggaccugaa gaacggaggc cagcccgucg     3420

ccggggagga uggacaggcu gccgacggcu ccaugcaacc gacaucuugg agacaggaac     3480

cucagcucug cgggauggga accgagcagg gcuguuggau ucccguuagc uccgauaaag     3540

gcagcugccc ucaagugaug gaacggucuu uucacaugcc cuccuacggg acacagaccc     3600

uggagggagg cguggaaaag ccccauagcc uucugucugc caauccucuc uggcagcaac     3660

gcgcucugga cccgccccac cagauggagc ugacgcagug aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  4310
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt5)

<400>  4310
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggca gacggaugga gaugcugugc gcugggcgcg      120

ugcccgcccu ccugcuuugu cugggauucc accuccugca ggcgguccuu agcacaacgg      180

uuaucccuuc cugcauuccg ggcgaaucua gcgacaacug uaccgcucug gugcaaacag      240

aggauaaucc cagaguggcc caggucucca ucaccaagug cucuagcgac augaacgggu      300

acugucucca uggacagugc auuuaucugg uggauauguc ccagaauuac ugucggugcg      360

aaguuggcua uacaggggug cgcugugagc acuuuuuccu gaccguccau caaccucucu      420

cuaaagaaua cguggcccug acaguuaucc uuauuauccu guuucucauc accguggucg      480

gaagcacgua uuacuucugc agaugguauc ggaaccgcaa guccaaagag cccaagaaag      540

aguacgaaag agugaccagc ggcgacccug agcugcccca ggugugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  4311
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt5)

<400>  4311
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgagggcg aaaucaccac auucacggcu cugaccgaga      120

aguuuaaccu gcccccuggg aauuacaaaa agccgaaacu ccuuuauugc agcaacggag      180

gccacuuccu gcggauucuc cccgacggga caguggaugg aaccagagac cgcuccgauc      240

agcauaucca acugcagcuu ucugccgaaa gcgucggcga gguuuacauu aaguccacag      300

aaaccgggca guaucuggcg auggacacag auggacuccu guacggcucu cagaccccua      360

augaggagug ucuguuucuc gaaagacugg aggaaaacca cuauaauacg uacaucagca      420

aaaagcaugc ugagaagaac ugguucgugg gccuuaaaaa gaaugggucc ugcaaacggg      480

gaccccgcac ccacuauggc caaaaggcca uucuguuucu cccucugccc gugucuagcg      540

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  4312
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt5)

<400>  4312
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggcgucg ggggaggcga cguugaggau gugaccccca      120

gaccuggggg augccagauc agcggccgcg gggcccgggg auguaacggc auuccgggcg      180

cugccgcgug ggaagcugcc cugcccagac ggcgcccuag acggcacccc uccgugaauc      240

cucgcucuag agccgcuggg agcccccgga cacgcggaag acggacggag gaacgcccuu      300

ccggcucuag acucggggac cggggacgcg gcagagcccu gcccggggga cggcuuggcg      360

gcagagggcg cggacgggcu cccgagagag ucggcgggcg cggacggggc agagggaccg      420

ccgcgccucg cgccgcuccc gccgcucggg gaagcagacc uggccccgcc ggcacaaugg      480

cggccggguc caucaccaca cugccggcuc ucccugaaga uggaggcucu ggggccuucc      540

cgccuggaca uuuuaaggac cccaaacgcc uguacugcaa gaacggcggg uucuuucuuc      600

ggauucaccc cgauggcaga guggacggag uucgcgagaa aagcgauccu cauaucaagc      660

ugcaacucca ggcugaggaa cggggcgugg ucuccauuaa aggggugugu gccaauagau      720

aucuggccau gaaggaggac ggacggcugc ucgcuagcaa gugcguuacc gaugaauguu      780

ucuuuuucga gcgccuggag ucuaacaauu acaacacaua uagaucccgg aaauacacca      840

gcugguaugu ggcgcuuaag agaacgggcc aguacaaacu ggggucuaag accggaccgg      900

gccagaaagc cauccucuuu cugcccaugu ccgcuaagag cugaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  4313
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt5)

<400>  4313
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uccugaccug gauucucccc acacugcuuu      120

acagaagcug cuuccauauc auuugucugg ugggcacgau cucccucgcc ugcaacgaca      180

ugaccccuga gcagauggcu acaaauguca acuguucuag cccggaacgg cacacccgcu      240

ccuaugauua cauggaaggg ggagacauua gaguucggcg ccuguuuugc agaacacaau      300

gguaucuucg gaucgauaaa cgcggcaagg ugaaagggac ccaggagaug aagaauaacu      360

acaauaucau ggagauuaga acaguggccg ucggaaucgu ggcgauuaaa ggcguugaau      420

cugaguucua ucuggcuaug aacaaggagg ggaagcucua cgccaaaaag gaauguaaug      480

aggacugcaa cuuuaaagaa cugauccugg agaaucauua uaacaccuac gccagcgcua      540

aguggacgca caauggaggc gagauguucg uggcccucaa ccagaaaggc auucccgucc      600

gggggaagaa gaccaaaaag gaacagaaaa cagcucauuu ucugccuaug gccaucaccu      660

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  4314
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt5)

<400>  4314
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugcucc ccagcguggu ccugaaacuu uuccuggccg      120

cuguucucuc cgcccuggug accggcgagu cucuugaaag acugcggcgc gggcucgcgg      180

cuggaacaag caacccugac ccgcccacgg uguccaccga ucagcugcug ccucucggcg      240

ggggaagaga ccggaagguc cgcgaucugc aagaggccga ccuugaucug cucagaguga      300

cacugucuag caaaccccag gcccuugcua ccccuaauaa ggaggaacac ggcaaacgga      360

agaagaaagg gaagggacug ggcaaaaagc gcgaccccug ccucagaaaa uacaaggauu      420

uuuguaucca uggcgaaugc aaguauguua aagagcugcg ggccccuucc uguauuugcc      480

acccggggua ccauggagag cgcugucacg gccugucucu ccccguggaa aacagacugu      540

auacauacga ccauaccaca auccuugcug ucguggccgu ugugcugagc uccgucugcc      600

uccuggugau uguggggcuu cugauguucc gguaucaccg cagaggaggc uacgaugucg      660

agaaugaaga gaagguuaaa cucgggauga ccaacagcca cugaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  4315
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt5)

<400>  4315
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccugcuu cugcagcacg      120

uccuccugca ucuucugcuc cugccuaucg cuauuccgua cgccgagggc caaagaaaac      180

ggcgcaacac aauccacgag uucaagaaaa gcgcgaagac gacccugauu aaaaucgacc      240

ccgcucucaa gauuaagacc aaaaagguua auaccgccga ucagugcgcc aacagaugua      300

cacggaauaa agggcugccu uuuaccugca aggcuuucgu guuugacaaa gcccgcaagc      360

agugucuuug guuccccuuu aacuccaugu cuagcggagu gaagaaagag uucggccaug      420

aauuugaucu guaugagaau aaggacuaca ucagaaacug caucauuggg aaaggacggu      480

ccuauaaggg cacagucucu aucaccaaaa gcgggauuaa gugucagccu ugguccucua      540

ugauccccca cgaacauagc uuccucccuu ccagcuaccg cggaaaagau cugcaagaga      600

auuauugcag aaacccgcgg ggcgaggaag gcgggcccug guguuuuacg ucuaauccug      660

aggugcgcua cgaaguuugc gacauucccc aguguuccga gguggagugc augaccugua      720

acggagaaag cuauagaggc cuuauggauc acacagaguc ugggaagauc ugccagcggu      780

gggaccacca gaccccucau cgccacaagu uccugcccga aagauacccg gauaaaggau      840

uugacgauaa uuacugccgg aacccugacg gccaaccccg cccuuggugu uauacacucg      900

auccccauac aagaugggaa uacugcgcua uuaagacgug ugccgacaau acaaugaacg      960

acaccgaugu cccccuggaa acaaccgagu gcauccaggg gcagggagag ggcuaucggg     1020

gcaccgugaa uacaaucugg aacgggauuc cuugucagag augggacucc caauacccgc     1080

acgaacacga uaugacgccc gagaacuuca aaugcaagga ccugcgcgaa aauuauuguc     1140

ggaacccuga uggaagcgag ucucccuggu gcuuuaccac agacccuaau aucagaguug     1200

gcuacuguuc ccagauuccc aacugcgaua ugagccaugg gcaggacugu uaucgcggaa     1260

auggcaaaaa cuacaugggg aaucucuccc aaacccgguc uggacugaca ugcagcaugu     1320

gggauaagaa cauggaagac cuucacagac auaucuucug ggagccggau gcguccaagc     1380

ugaaugagaa cuacugccgc aauccugacg acgaugccca cggccccugg uguuauaccg     1440

gcaacccucu cauucccugg gacuacugcc cuaucagccg gugugaaggg gauacgacac     1500

ccaccaucgu gaaucuggac cauccgguca uuucuugcgc uaaaaccaag cagcuuagag     1560

uggugaacgg aaucccuaca cgcaccaaua uuggcuggau ggucucccug cgguauagaa     1620

acaaacacau cuguggggga agccucauua aggagucuug gguucugaca gcccgccagu     1680

gcuuccccag ccgggaucug aaagacuacg aggcuuggcu cggcauccac gaugugcaug     1740

ggagaggcga cgaaaagugu aaacaggugc ugaacgucuc ccaacuugug uauggacccg     1800

aaggcucuga ucugguucuc augaagcugg cccggccugc ggugcuugac gauuuuguca     1860

gcacgaucga ccugccgaau uacgggugca ccauucccga gaagacaucc uguagcgugu     1920

auggaugggg cuacaccggg cucaucaacu acgauggacu gcugcgcguu gcccaccucu     1980

auauuauggg caaugagaaa ugcucucagc aucacagagg gaaggugaca cugaacgaau     2040

ccgagaucug ugcuggcgcc gagaaaauug gaagcggccc uugcgaaggg gacuacggag     2100

gcccccuugu cugcgagcag cacaagaugc ggauggugcu gggggucauc gugccuggaa     2160

gaggcugugc uauucccaau cgcccuggga ucuucguucg gguggccuau uacgccaagu     2220

ggauccauaa aauuauccuc accuauaagg ucccccaguc uugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  4316
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt5)

<400>  4316
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggcug ccgcgaucgg cauugaccug gggaccacau      120

acagcugcgu gggagucuuc cagcacggca aaguugagau cauugcuaac gaucaaggga      180

auagaacgac ccccuccuau guggccuuua cagacaccga acggcucauc ggagaugccg      240

cuaagaacca gguggcccug aauccucaga acacagucuu cgacgcuaaa cgccuuauug      300

gcagaaaguu uggggauccg gugguucagu cugacaugaa acauuggccc uuccaaguga      360

ucaaugaugg agacaagccu aagguccagg ugagcuacaa aggcgagacc aaggccuuuu      420

aucccgaaga gaucuccucu augguucuga caaaaaugaa ggaaauugcg gaggccuacc      480

ucggcuaucc ugugaccaac gcugucauca cggugcccgc cuacuucaau gauagccagc      540

ggcaggcuac caaagacgcc ggggugauug cgggacugaa cguccuucgc aucauuaaug      600

agccuacagc cgcugccauc gcuuauggcc uggauagaac cgggaaggga gaacggaacg      660

uucucauuuu ugaccugggc gggggaacau ucgauguguc cauccugacc aucgacgacg      720

gcauuuuuga ggugaaggcc acggccggcg auacacaccu cgggggagaa gacuucgaua      780

aucgccuggu caaccauuuu guggaggagu ucaaaagaaa gcacaaaaag gacaucucuc      840

aaaauaaacg ggcuguucgc agacuucgga ccgcguguga acgcgccaag agaacacuga      900

gcuccagcac ccaggcuucu cucgagauug auucccuguu ugaaggcauc gacuucuaca      960

ccagcauuac acgggcccgc uucgaggaac uuugcucuga ucuguuuaga uccacgcucg     1020

agccggugga gaaagcccug cgggacgcua agcuggauaa ggcccagauc caugaccucg     1080

uccugguugg gggaagcacc agaaucccca aagugcagaa acuucugcaa gauuucuuua     1140

acggccgcga ccucaauaag ucuauuaacc cugacgaagc gguggcuuac ggggccgccg     1200

uccaggcugc cauccugaug ggagauaagu ccgagaacgu gcaggaccuu cugcuccugg     1260

augucgcucc ccugagccuc ggccuggaaa cagccggcgg ggugaugacc gcgcuuauua     1320

aacggaauag cacaaucccu accaagcaaa cgcagauuuu cacaaccuau ucugacaacc     1380

agcccggagu ucugauccag guguacgagg gcgaaagagc caugaccaag gauaauaacc     1440

uccuggggcg cuuugagcuu agcggaaucc cgccugcucc ccggggcguc ccucaaauug     1500

aggugacauu cgacaucgau gccaauggga uucugaacgu uaccgcuaca gacaaaucca     1560

cgggcaaggc caauaaaauc accauuacaa acgauaaggg aagacucagc aaagaagaga     1620

ucgaacgcau ggugcaggag gcggaaaagu auaaggccga ggacgagguc cagcgggaaa     1680

gagugucugc uaaaaaugcc cuggaguccu acgcuuuuaa caugaagucc gccguggaag     1740

augagggccu gaaagggaag auuucugagg ccgacaaaaa gaagguucuc gauaaauguc     1800

aggaagucau cagcuggcug gacgcuaaua cccuugcgga gaaggacgag uucgaacaca     1860

aacgcaagga acuggagcaa gugugcaacc ccaucauuuc cggacucuau cagggcgccg     1920

ggggacccgg cccugggggc uuuggagcuc agggcccgaa agggggaucu ggcagcgggc     1980

ccacaaucga ggaaguggau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4317
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt5)

<400>  4317
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggcug ccgcgaucgg cauugaccug gggaccacau      120

acagcugcgu gggagucuuc cagcacggca aaguugagau cauugcuaac gaucaaggga      180

auagaacgac ccccuccuau guggccuuua cagacaccga acggcucauc ggagaugccg      240

cuaagaacca gguggcccug aauccucaga acacagucuu cgacgcuaaa cgccuuauug      300

gcagaaaguu uggggauccg gugguucagu cugacaugaa acauuggccc uuccaaguga      360

ucaaugaugg agacaagccu aagguccagg ugagcuacaa aggcgagacc aaggccuuuu      420

aucccgaaga gaucuccucu augguucuga caaaaaugaa ggaaauugcg gaggccuacc      480

ucggcuaucc ugugaccaac gcugucauca cggugcccgc cuacuucaau gauagccagc      540

ggcaggcuac caaagacgcc ggggugauug cgggacugaa cguccuucgc aucauuaaug      600

agccuacagc cgcugccauc gcuuauggcc uggauagaac cgggaaggga gaacggaacg      660

uucucauuuu ugaccugggc gggggaacau ucgauguguc cauccugacc aucgacgacg      720

gcauuuuuga ggugaaggcc acggccggcg auacacaccu cgggggagaa gacuucgaua      780

aucgccuggu caaccauuuu guggaggagu ucaaaagaaa gcacaaaaag gacaucucuc      840

aaaauaaacg ggcuguucgc agacuucgga ccgcguguga acgcgccaag agaacacuga      900

gcuccagcac ccaggcuucu cucgagauug auucccuguu ugaaggcauc gacuucuaca      960

ccagcauuac acgggcccgc uucgaggaac uuugcucuga ucuguuuaga uccacgcucg     1020

agccggugga gaaagcccug cgggacgcua agcuggauaa ggcccagauc caugaccucg     1080

uccugguugg gggaagcacc agaaucccca aagugcagaa acuucugcaa gauuucuuua     1140

acggccgcga ccucaauaag ucuauuaacc cugacgaagc gguggcuuac ggggccgccg     1200

uccaggcugc cauccugaug ggagauaagu ccgagaacgu gcaggaccuu cugcuccugg     1260

augucgcucc ccugagccuc ggccuggaaa cagccggcgg ggugaugacc gcgcuuauua     1320

aacggaauag cacaaucccu accaagcaaa cgcagauuuu cacaaccuau ucugacaacc     1380

agcccggagu ucugauccag guguacgagg gcgaaagagc caugaccaag gauaauaacc     1440

uccuggggcg cuuugagcuu agcggaaucc cgccugcucc ccggggcguc ccucaaauug     1500

aggugacauu cgacaucgau gccaauggga uucugaacgu uaccgcuaca gacaaaucca     1560

cgggcaaggc caauaaaauc accauuacaa acgauaaggg aagacucagc aaagaagaga     1620

ucgaacgcau ggugcaggag gcggaaaagu auaaggccga ggacgagguc cagcgggaaa     1680

gagugucugc uaaaaaugcc cuggaguccu acgcuuuuaa caugaagucc gccguggaag     1740

augagggccu gaaagggaag auuucugagg ccgacaaaaa gaagguucuc gauaaauguc     1800

aggaagucau cagcuggcug gacgcuaaua cccuugcgga gaaggacgag uucgaacaca     1860

aacgcaagga acuggagcaa gugugcaacc ccaucauuuc cggacucuau cagggcgccg     1920

ggggacccgg cccugggggc uuuggagcuc agggcccgaa agggggaucu ggcagcgggc     1980

ccacaaucga ggaaguggau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4318
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt5)

<400>  4318
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaccgcua agggcaucgc cauugggauc gaccugggaa      120

caacguacag cugcgugggc gucuuccagc acgggaaggu ugagauuauc gcgaacgauc      180

aaggaaauag aaccacaccc uccuaugugg cuuuuaccga cacagaacgg cucauuggcg      240

augccgccaa gaaccaggug gcuaugaauc cucagaacac cgucuucgac gccaaacgcc      300

ugaucgggag aaaguuuaau gauccggugg uucaggcuga caugaaacuu uggcccuucc      360

aagugaucaa cgagggaggc aagccuaagg uccugguguc uuacaaaggc gaaaauaagg      420

ccuuuuaucc cgaggaaauu agcuccaugg uucucacaaa acugaaggag accgcggagg      480

ccuuccuugg gcauccugug acgaacgcug ucaucaccgu gcccgccuac uuuaaugauu      540

cucagcggca ggcuacaaaa gacgccggag ugauugcggg ccugaacguc cuccgcauca      600

uuaaugaacc uaccgccgcu gccaucgcuu augggcugga uaagggaggc cagggggaga      660

gacacguucu gauuuucgac cucggaggcg gcacauuuga ugugagcauc cugaccaucg      720

acgaugggau uuucgaagug aaggccacgg ccggagacac acaucuuggc ggggaggacu      780

uugauaaccg gcuggucucc cacuucgugg aggaauuuaa acgcaagcau aaaaaggaca      840

ucucucaaaa uaaaagagcu guucggcgcc ucagaaccgc gugugagcgg gccaagcgca      900

cacugagcuc cagcacccag gcuaaccuug aaauugauuc ucuguacgag ggaaucgacu      960

ucuauaccuc cauuacaaga gcccgguucg aggaacucug cgccgaucug uuucgcggca     1020

cgcuggagcc gguggaaaaa gcucucagag acgccaagau ggauaaggcg aaaauccacg     1080

acaucguccu gguuggggga agcacccgga uucccaaggu gcagagacuu cugcaggauu     1140

acuucaaugg ccgcgaccuc aacaaaucua ucaacccuga ugaggcugug gccuacggcg     1200

ccgcugucca agccgcuauu cugauggggg acaaguccga aaaagugcag gaccuucugc     1260

uccuggaugu cgcgccccug agccucggac uggagacagc cggcggggug augaccgccc     1320

uuaucaagcg gaauagcaca auuccuacca agcagacgca aaucuuuaca accuauuccg     1380

acaaccagcc cggaguucug auccaggugu acgaaggcga gagagcuaug accaaagaua     1440

auaaccuccu ggggcgcuuc gaccuuacag gcauuccgcc ugcuccccgg ggagucccuc     1500

agaucgaggu gaccuuugau auugacgcca auggcauccu gaacguuaca gccacggaua     1560

agagcaccgg gaaagugaau aagauuacaa ucaccaacga caaaggaaga cucuccaagg     1620

aagagauuga acgcaugguc cuggaugcgg agaaguauaa agccgaagac gaggugcaac     1680

gggagaagau cgcugccaaa aaugcucugg aaucuuacgc cuucaacaug aagucugugg     1740

uuuccgauga gggccucaaa gggaagauca gcgaaucuga caagaauaaa auucuggaua     1800

aguguaacga gcuucugucc uggcucgagg ucaaucagcu ggccgaaaaa gacgaguuug     1860

accacaagag aaaagaacug gagcagaugu gcaaccccau cauuacaaaa cuuuaucagg     1920

gaggcuguac cgggcccgcu ugcggcacgg gauacgugcc uggccgcccg gcgaccgggc     1980

ccacaaucga agagguggau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4319
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt5)

<400>  4319
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgccagag gccccgcuau cgggauugac cugggaacca      120

cauacuccug cgugggcguc uuccagcacg ggaagguuga gaucauugcc aacgaucaag      180

gaaaucggac gaccccuucu uauguggcgu uuacagacac cgaacgccuc aucggcgaug      240

cugccaaaaa ccagguggcc augaauccga caaacaccau uuucgacgcu aagagacuga      300

ucgggcggaa auuugaggau gccacagucc agagcgacau gaagcauugg cccuuccgcg      360

ugguuuccga aggaggcaaa ccuaaggugc aggucgagua caagggcgaa accaaaacgu      420

uuuuccccga ggagaucucu agcauggugc uuaccaagau gaaagaaauu gcugaggccu      480

aucugggagg aaagguucac uccgcgguga ucacaguccc ugccuacuuu aaugauucuc      540

aaagacaggc uaccaaagac gccggcacaa uuaccgggcu caacgugcug cggaucauua      600

augaacccac ggcugccgcg aucgccuaug gacuugauaa gaagggcugu gcugggggag      660

agaaaaacgu gcugauuuuc gaccucggcg gcgggacauu ugaugucagc auccugacca      720

ucgaggacgg aauuuucgaa guuaagucca cagccggcga uacccaucuu gggggagagg      780

acuuugacaa ucgcauggug agccaccucg cugaagaguu caaaagaaag cauaaaaagg      840

auaucggccc uaacaaacgg gccgugcgca gacugcggac cgccugcgaa cgcgcuaaga      900

gaacacuuuc uuccagcacg caggcgucua uugagaucga cucccuguac gagggggucg      960

auuuuuauac cagcauuaca cgggcccgcu ucgaggaacu caaugcugac cuguucagag     1020

gaacccuuga accgguggag aaggcccugc gggaugccaa acucgacaag ggccagaucc     1080

aagaaaucgu ucuggugggc gggucuacac gcauucccaa aauccagaag cugcuccagg     1140

acuuuuucaa cggaaaagag cugaauaagu ccauuaaccc ugaugaggcu gucgccuacg     1200

gcgcggcugu gcaggccgcc auccuuauug gggauaagag cgaaaauguu caagaccugc     1260

uccugcuuga ugugacgccc cugucccucg gaaucgagac cgcuggcggg gucaugacac     1320

cucugaucaa aagaaacacc accauuccca caaagcagac ccagacauuu acgaccuacu     1380

cugacaacca aagcuccgug cugguccagg uguaugaagg cgagcgggcc augacaaaag     1440

acaauaaccu ccugggaaag uucgaucuua ccggcauccc gccugcuccc agagggguuc     1500

cucagauuga agugacauuu gacaucgaug ccaaugggau ucugaacguc accgcggccg     1560

acaaaagcac gggcaaggag aauaagauca ccauuacaaa cgauaaaggg cgccucucua     1620

aggacgauau cgaccggaug gugcaggagg cugaaagaua caaauccgag gaugaagcca     1680

aucgcgaccg gguugcugcc aagaacgcgc uggagagcua uaccuacaau aucaaacaaa     1740

caguggagga ugaaaagcug agaggaaaga uuucugagca ggacaaaaac aagauccugg     1800

auaaauguca ggaagucauu aauuggcucg accgcaacca gauggccgag aaggacgaau     1860

augagcacaa acaaaaggag cuggaacggg ugugcaaucc caucauuagc aaacuguacc     1920

agggcgggcc cggcggaggc uccgggggag gcgggucugg agcuagcggc gggccuacca     1980

ucgaggaagu ggauugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  4320
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt5)

<400>  4320
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccag uccugcuacg      120

uugccguggc uagagccgga ggcauugaga ccaucgcgaa cgaauauucu gaucggugua      180

cacccgcuug cauuagcuuu gggccuaaga aucgcuccau cggagccgcc gcuaaaucuc      240

aagugauuag caacgccaag aauacggucc agggcuucaa aagauuucac gggcgggcuu      300

ucuccgaccc guuuguggag gccgaaaagu cuaaccucgc guacgauauc guucagcugc      360

ccaccggacu uacaggcauc aaagugaccu auauggagga agaacgcaau uucacaaccg      420

agcaggucac agccaugcug cucagcaagc ugaaggaaac cgcugagucc gugcuuaaaa      480

agccuguugu ggacuguguc gugagcgugc ccugcuuuua cacggaugcc gaaagacggu      540

cugucaugga cgcuacccaa auugccggcc ugaacugucu ccgccugaug aaugagacaa      600

ccgcgguugc ccuggcuuau gggaucuaca aacaggaucu cccugcccug gaggaaaagc      660

ccagaaacgu gguguucguc gacaugggac auuccgcuua ucaggugagc guuugcgccu      720

uuaaucgggg caaacuuaag gugcuggcca cagcuuucga uaccacgcuc gggggacgca      780

aguuugacga gguccuggug aaccacuucu gugaagaguu uggcaaaaag uacaaacuug      840

auauuaaguc uaaaaucaga gcgcugcucc ggcuguccca ggaaugcgag aagcugaaaa      900

agcucaugag cgccaaugcu ucugaccugc cucuuuccau ugaguguuuc augaacgaug      960

uugacgugag cgggacaaug aaucgcggaa aguuccugga aaugugcaac gaccuccugg     1020

ccagagucga gccgccccuu cgguccgugc uggaacaaac caaacucaag aaagaggaua     1080

ucuacgccgu cgaaauugug ggcggcgcua cacgcauccc ugccguuaag gagaaaaucu     1140

cuaaguuuuu cgggaaggag cugagcacca cccugaaugc ggacgaagcu gugacaagag     1200

gaugugcccu ccagugcgcc auucuguccc ccgcuuuuaa aguccgggag uucagcauca     1260

cggauguggu uccuuauccc auuucucuua gauggaacuc cccggccgaa gagggcagcu     1320

cugacugcga aguguuuagc aagaaccaug cugccccuuu cuccaaaguc cugaccuuuu     1380

accgcaagga gcccuucaca cucgaggcgu auuacucuag cccucaggau cugcccuauc     1440

ccgacccugc caucgcucag uuuuccgugc aaaaagugac cccgcagagc gaugggucuu     1500

ccagcaaggu uaaggucaaa gugcggguga auguccacgg aauuuucucu guguccagcg     1560

ccucccuugu ugaagugcau aagucugagg aaaacgagga gcccauggaa acagaccaga     1620

augcuaaaga ggaagagaag augcaagucg aucaggagga gccucacgug gaggaacagc     1680

agcaacagac ccccgccgag aacaaagcgg aaagcgagga aauggagacg ucccaggccg     1740

gcucuaagga caagaaaaug gaucagccuc cccaagcuaa gaaagccaag guuaaaacaa     1800

gcaccgugga ccugccgauc gagaaucagc uccuguggca gaucgacaga gaaaugcuga     1860

accucuacau ugagaaugaa gggaagauga ucaugcagga uaaacuggag aaggaacgca     1920

acgacgcuaa gaaugccguc gaggaguaug uguacgaaau gcgggauaaa cuuuccggag     1980

aguacgaaaa guuuguuagc gaggacgaua gaaacucuuu cacccugaaa cucgaggaca     2040

cagaaaauug gcuguaugag gauggcgaag accaaccuaa acagguguac gucgauaagc     2100

uggccgagcu uaagaaccuc ggccagccca uuaagauccg cuuucaggaa uccgaggagc     2160

ggccuaaacu guucgaggaa cuggggaagc aaauucagca guauaugaaa aucaucagcu     2220

cuuucaagaa uaaagaagac caauacgauc accucgacgc ugcggauaug accaaggugg     2280

agaaguccac aaacgaagcc auggagugga ugaauaacaa acugaaccuu cagaauaagc     2340

agagccugac gauggacccc guggucaaau cuaaggagau ugaagcuaaa aucaaggagc     2400

ucaccagcac auguuccccu auuaucagca agcccaaacc gaagguugaa ccucccaaag     2460

aggaacagaa gaacgccgag caaaauggac ccguggacgg ccagggggau aacccuggac     2520

cgcaggccgc ugagcagggc accgacacag ccgugcccuc ugauuccgac aaaaagcugc     2580

cugaaaugga uauugacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  4321
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt5)

<400>  4321
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccuc aacugcuaca      120

uugccguugc uagauccgga ggcaucgaga ccauugccaa ugaauauucu gaucggugua      180

cacccgcgug caucagccug gggucccgca cgagagcuau uggaaacgcc gccaagucuc      240

agaucgugac caaugugcgg aacacaaucc acggcuuuaa aaagcugcau gggcgcagcu      300

ucgacgaucc uauuguccaa accgagagaa uccggcuucc guacgaacuc cagaaaaugc      360

ccaauggauc cgcuggcgug aagguucgcu aucuggagga agagagaccu uuugccauug      420

aacaggugac aggcaugcuu cuggcuaaac ucaaggagac cucugagaac gcccugaaga      480

aacccgucgc ggacugugug aucagcauuc cuuccuucuu uacagaugcc gaacggcgca      540

gcguuauggc ugccgcucag guggccgggc ugaauugccu cagacugaug aacgagacca      600

cggcggucgc ccuugcuuac ggaaucuaua agcaagaccu gcccccucuc gaugagaaac      660

cgcggaaugu gguguucauu gacaugggcc acucugccua ccagguccug guuugugcuu      720

uuaacaaggg gaaacuuaag gugcuggcca ccacauucga ucccuaucuc ggaggccgca      780

auuuugacga agcccuggug gauuacuucu gcgacgaguu uaagaccaaa uacaagauca      840

acgucaaaga aaauuccaga gcucugcucc ggcuguauca ggagugugaa aaacuuaaga      900

agcugaugag cgcgaacgcc ucugaucucc cucugaauau cgagugcuuc augaacgacc      960

uugacguguc cagcaaaaug aaccgcgcuc aguuugagca acugugugcc ucucuccugg     1020

ccagaguuga acccccucug aaggcuguga uggagcaggc caaucuccag cgggaagaua     1080

uuuccagcau cgagauuguc gggggagcga caagaauccc cgcugugaag gaacagauua     1140

ccaaauucuu ccugaaggac aucuccacga cacuuaacgc cgaugaggcc guugcucgcg     1200

gcugcgcccu gcaaugugcu auccucucuc cggccuuuaa agugcgggag uucagcauua     1260

ccgaccuggu cccuuacucc aucacacuua gauggaagac cagcuuugaa gauggcucug     1320

gggagugcga aguguucugc aaaaaucauc ccgcgccuuu uuccaagguc auuaccuucc     1380

acaagaaaga gcccuuugaa cuggaggccu ucuauacaaa ccuccaugag gugcccuacc     1440

cugacgcucg caucggcagc uuuacgauuc agaauguuuu cccgcagucu gauggagaca     1500

gcuccaaggu gaaagucaag gugcggguua acauccacgg gaucuuuucu guggccagcg     1560

cuuccgucau ugaaaaacaa aaucuggagg gagaucacag cgacgccccc auggaaaccg     1620

agacaucuuu caagaacgag aauaaggaua acauggacaa aaugcaagug gaccaggaag     1680

agggccauca gaagugucac gcggaacaua ccccugagga agagaucgau cacacagggg     1740

ccaaaaccaa guccgcugug agcgacaaac aggauagacu gaaucagacg cucaagaagg     1800

gaaaaguuaa gucuauugac cugcccaucc aguccagccu uugccgccag cugggccaag     1860

aucuccugaa cuccuauauu gagaaugaag gcaaaaugau caugcaggac aagcuggaga     1920

aagaacggaa cgaugccaag aaugcugucg aggaauacgu guaugacuuu agagaucgcc     1980

uugggacagu guacgagaaa uucauuaccc cugaggaccu cucuaagcug agcgccgucc     2040

uggaagauac cgagaacugg cucuacgaag acggagagga ucagcccaaa cagguguaug     2100

uugacaagcu gcaagaacuu aagaaauacg gccagccgau ccagaugaag uauauggagc     2160

acgaggaacg gccuaaagcc cugaacgacc ucgggaagaa gauccagcug gugaugaaag     2220

ucauugaggc uuacagaaau aaggaugaac gcuaugacca ucuggauccc acagagaugg     2280

agaaagugga aaaguguauc uccgacgcga ugucuuggcu uaacagcaaa augaaugccc     2340

aaaacaagcu cucccugacc caggauccug uugugaaggu cagcgagauu guggcuaaau     2400

cuaaggaacu ggacaauuuc ugcaacccca ucauuuacaa accuaagccc aaagccgagg     2460

uuccggaaga uaagccuaag gccaauuccg agcacaacgg acccauggac ggccagagcg     2520

ggacagagac gaaaucugau uccaccaagg acagcucuca acauacaaaa agcuccggcg     2580

aaauggaggu ggauugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  4322
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt5)

<400>  4322
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugagcc ucguggccgc uaugcugcuu cugcucuccg      120

ccgcgagagc ugaggaagag gacaaaaagg aagaugucgg caccguugug gggaucgacc      180

ugggaacaac guacucuugc gugggcgucu ucaaaaacgg gcggguggag auuaucgcca      240

augaucaggg aaaccgcauu acccccagcu auguugccuu uacaccugaa ggcgagagac      300

uuaucgggga cgcugccaag aaucaacuga ccuccaaccc ggagaauaca guguucgaug      360

cuaaacggcu cauuggacgc accuggaacg accccucugu ccagcaggau aucaaguuuc      420

ugccuuucaa ggugguugaa aagaagacaa aacccuacau ccagguggac auuggcggcg      480

ggcaaaccaa gacguuugcc ccugaggaaa ucagcgcgau gguccugacc aaaaugaagg      540

agacagccga ggcuuaucuc ggaaagaaag ugacccacgc cguggucaca guucccgcuu      600

acuucaauga ugcccagaga caggcgacca aggacgccgg cacgauugcu gggcugaacg      660

ugaugcggau cauuaaugaa ccuacagccg cugccaucgc cuauggacuu gauaaacgcg      720

agggcgaaaa gaacauucug guguuugacc ucgggggagg caccuucgau gucucccugc      780

uuacaaucga caauggcgug uuugagguug uggcuaccaa cggggacacc caucugggag      840

gcgaagauuu cgaccagaga gucauggagc acuuuaucaa acucuacaag aaaaagacag      900

ggaaggaugu gcggaaagac aaucgcgcgg uucaaaagcu gagacgggag guggaaaaag      960

ccaagcgcgc ucugucuagc cagcaucagg ccagaauuga gaucgaaucc uucuaugagg     1020

gagaagauuu uagcgagacg cucacccggg ccaaauucga ggaacugaac auggaccuuu     1080

uccgcucuac aaugaagccg guccagaagg ugcuggagga uuccgaccuc aaaaagagcg     1140

auauugacga aaucguccug gugggcgggu cuacccggau ucccaaaauc caacagcuug     1200

uuaaggaguu uuucaaugga aaagaaccuu ccagaggcau caaccccgau gaggcugugg     1260

ccuacggcgc ggcuguccag gccggggugc ugagcggaga ccaagacaca ggcgaucucg     1320

uucugcugga cguguguccu cucacccugg ggauugagac ggucggaggc gugaugacaa     1380

aacuuauccc cagaaacacc gugguuccga ccaagaaauc ucagaucuuu uccacagcca     1440

gcgauaauca gccuaccguc acaauuaagg uguacgaagg ggagcgcccc cugacgaaag     1500

acaaccaccu ccugggcacc uucgaucuua caggcauucc ucccgcuccc cggggagugc     1560

cucagaucga agucaccuuu gagaucgacg ugaaugggau ucugagaguu acagccgagg     1620

auaagggaac cggcaacaaa aauaagauca cgauuaccaa cgaccaaaau cgccucacac     1680

cggaagagau cgaacggaug gugaacgaug cugagaaguu cgccgaagag gacaaaaagc     1740

ugaaagagag aauugauacc cgcaaugaac uggaguccua ugcguacucu cucaagaacc     1800

agaucgggga caaagaaaag cugggaggca aacuuagcuc cgaggauaag gaaacaaugg     1860

agaaggccgu cgaggagaaa auugaauggc uggaaagcca ucaggacgcu gacaucgagg     1920

auuuuaaggc caaaaagaaa gaacucgagg agaucgugca gcccauuauc ucuaagcugu     1980

auggguccgc uggcccuccc ccuaccggag aagaggacac ggccgaaaag gaugagcugu     2040

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  4323
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt5)

<400>  4323
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gagagcuggc ugugggcauc gaccucggga      120

ccacauacag cugcgucgga guuuuccaac agggccgggu ggaaauucug gccaacgauc      180

aggggaaucg cacgaccccu uccuaugugg cguuuacaga caccgagaga cuugucggag      240

augcugccaa gucucaggcc gcucugaacc cgcacaauac aguguucgac gccaaacggc      300

ucaucggccg caaguuugcu gauaccacag uucaaagcga caugaaacau uggcccuuca      360

gaguggucuc cgaaggggga aagccuaaag ugcggguuug uuaccgcggc gaggauaaga      420

ccuuuuaucc cgaagagauu ucuagcaugg ugcuguccaa gaugaaagag acggccgaag      480

cguaccuugg ccagccuguc aagcacgccg ugaucaccgu gcccgcuuau uucaacgacu      540

cucagagaca ggccacaaaa gaugcugggg ccauugcggg acugaauguc cuccggauca      600

ucaacgagcc uaccgccgcu gccauugcuu acggccugga ccgcagaggg gccggagaac      660

ggaauguucu gaucuuugau cucggcgggg gaacauucga cgugagcgug cuguccauug      720

augccggcgu cuuugaggug aaggcuaccg cgggcgacac gcaucuuggg ggagaggacu      780

ucgauaaccg ccugguuaau cacuuuaugg aagaguucag acggaaacau ggcaaggacc      840

ucagcgggaa caagcgcgcc cugagacggc uuagaacagc uugcgaacgc gccaaacgga      900

cccugucuuc cagcacacaa gccacccucg agaucgauuc ucuguuugaa ggaguggacu      960

ucuauaccuc cauuacaaga gcucgcuucg aggagcugug uagcgaucuc uuucggucua     1020

cgcuggaacc ggucgagaag gcccuuagag acgcgaaacu ggauaaggcu cagauccacg     1080

acgugguucu cgugggcggg uccacccgca uucccaaagu ccagaagcug cuucaggauu     1140

ucuuuaaugg aaaagaacug aacaagagca ucaauccuga cgaggccgug gccuacggcg     1200

cugccgucca agcugccgug cucaugggcg auaagugcga aaaaguucag gaccugcugc     1260

uccuggacgu ggcgccccuu ucccuggggc ucgagacagc cggaggcguc augaccacac     1320

ugauccagcg gaacgcuacc auuccuacga agcaaacaca gaccuucacc acauacucug     1380

auaaucagcc cgggguguuu auccagguuu augagggaga aagagccaug accaaagaca     1440

acaaccuucu gggccgcuuc gagcucagcg ggauuccgcc ugcuccccgg ggcgugccuc     1500

aaaucgaagu cacauuugau auugacgcca auggaauccu guccgugacg gcgaccgaua     1560

gaagcacagg caaggccaac aaaaucacca uuacaaauga caaggggcgc cugucuaagg     1620

aggaagugga gcggaugguu cacgaggcug aacaguacaa agccgaggau gaagcucaga     1680

gagaccgggu cgccgccaag aacucccucg aggcucaugu guuccacgug aaaggaagcc     1740

ugcaggagga aucucuucgc gauaagaucc ccgaggaaga cagacggaaa augcaagaua     1800

aguguagaga gguccuggcg uggcucgaac auaaucagcu ggccgagaag gaggaauaug     1860

agcaccagaa acgcgaacug gagcagauuu gccggcccau cuuuagcaga cuuuacggcg     1920

ggccuggagu gccgggcggg uccucuugug gcacccaagc ucgccaggga gaccccagca     1980

cgggcccuau uaucgaagag guugauugag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  4324
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt5)

<400>  4324
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gagagcuggc ugugggcauc gaccucggga      120

ccacauacag cugcgucgga guuuuccaac agggccgggu ggaaauucug gccaacgauc      180

aggggaaucg cacgaccccu uccuaugugg cguuuacaga caccgagaga cuugucggag      240

augcugccaa gucucaggcc gcucugaacc cgcacaauac aguguucgac gccaaacggc      300

ucaucggccg caaguuugcu gauaccacag uucaaagcga caugaaacau uggcccuucc      360

agguggucuc cgaaggggga aagccuaaag ugagaguuug uuaccggggc gaggauaaga      420

ccuuuuaucc cgaagagauu ucuagcaugg ugcuguccaa gaugaaagag acggccgaag      480

cguaccuugg ccagccuguc aagcacgccg ugaucaccgu gcccacauau uucucuaaca      540

gccagcgcca agcuaccaaa gacgccgggg cuauugccgg acugaagguc cucccuauca      600

ucaaugaggc gacagccgcu gccauugcuu acggccugga uagacgcggg gccggaaaac      660

ggaacguucu gaucuuugac cucggcgggg gaaccuucga uguguccgug cugagcauug      720

acgccggcgu cuuugaagug aaggcuacgg cgggcgauac acaucuuggg ggagaggacu      780

ucgacaauag acugguuaac cacuuuaugg aggaguuccg gcgcaagcau ggcaaagauc      840

ucucugggaa uaagagagcc cugcggcgcc uuagaaccgc uugcgagcgg gccaaaagaa      900

caccguccag cucuacccag gccacccugg aaaucgacuc ccucuuugag ggaguggauu      960

ucuauaagag cauuacacgc gcucgguucg aagaacugug uucugaccug uuuagaucca     1020

cgcucgagcc cgucgaaaaa gcccugcgcg augcgaaacu ugacaaggcu cagauccacg     1080

auuucgugcu gggcggggga cuccacagcc auccucaggg cgccgagguu gccgcuggcc     1140

ugcuucaacg gcagggggcc gaacaggagc accaacccug aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  4325
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt5)

<400>  4325
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaagggcc ccgccguggg gaucgaccug ggaaccacau      120

acuccugcgu cggcguuuuc cagcacggga aaguggagau uaucgcuaac gaucaaggaa      180

auagaacgac cccuucuuau guggccuuua cagacaccga acggcucauu ggcgaugcgg      240

cuaagaacca ggucgccaug aauccgacaa acaccguguu cgacgccaaa cgccugaucg      300

ggagacgguu ugaugacgcu guugugcaga gcgauaugaa gcauuggccc uucauggucg      360

ugaaugacgc cggacgcccu aaaguucagg uggaguacaa gggcgaaaca aaguccuuuu      420

aucccgagga agucucuagc auggugcuua ccaaaaugaa ggagauugcu gaggccuacc      480

ugggcaaaac ggugaccaac gcggucguua cagugccugc cuauuucaau gauucccaaa      540

gacaggcuac caaggacgcc gggacaaucg cuggacucaa cgugcugcgg aucauuaaug      600

aacccaccgc cgcggccauc gcuuacggcc uugauaaaaa ggucggggcc gagcgcaacg      660

ugcugauuuu ugaccucgga ggcgggacgu ucgauguuuc uauccugaca auugaagacg      720

gaaucuuuga ggugaagucu accgcuggcg acacacaccu gggcggggag gauuucgaca      780

auagaauggu caaccauuuu auugccgaau uuaaacggaa gcacaaaaag gauaucuccg      840

agaauaaacg cgccgugaga cggcuccgca ccgcuuguga aagagcgaag cggacccuga      900

gcagcuccac acaggccagc aucgagauug acucucuuua ugaaggaauc gauuuuuaca      960

cguccauuac ccgcgcuaga uucgaggagc ugaacgccga ccucuuccgg ggcacacugg     1020

auccuguuga aaaagcccuu agagacgcua agcuggauaa gagccagauc caugacauug     1080

ugcucgucgg gggaucuacc cgcaucccga aaauccaaaa gcugcugcag gauuucuuca     1140

auggcaaaga gcucaacaag uccauuaacc ccgacgaagc cguggcguac ggggcugccg     1200

uccaggccgc uauccugagc ggagacaaau ccgagaaugu gcaggaucuu cugcuccugg     1260

acguuacacc ucuuucucug ggcauugaaa ccgccggcgg ggugaugacg guccucauca     1320

agcggaacac aaccauuccc accaagcaaa cacagaccuu uacaacguau agcgauaauc     1380

agccuggagu gcugauccaa guuuacgagg gcgagagagc uaugaccaaa gacaacaauc     1440

ugcucgggaa guucgaacug acaggaaucc cgcccgcccc ucgcggcgug ccccagauug     1500

aggucaccuu ugauaucgac gcgaacggga uucuuaaugu guccgccgug gauaaaagca     1560

caggcaagga aaacaaaauc accauuacga augacaaggg acggcugucu aaggaggaua     1620

ucgaaagaau gguucaggag gcugagaaau auaaggccga agacgagaaa cagcgcgaua     1680

aggucuccag caaaaacucu cucgaaagcu acgcuuucaa uaugaaggcc accguggagg     1740

acgagaagcu gcaaggcaaa auuaacgaug aagacaagca gaaaauccuu gacaagugca     1800

augagaucau uaacuggcug gauaaaaauc agacagcgga aaaggaggaa uuugagcacc     1860

agcaaaaaga gcucgaaaag guguguaacc cuaucauuac caagcuguau caguccgccg     1920

ggggaaugcc cggcgggaug cccggaggcu ucccuggggg cggagcuccg cccucuggcg     1980

gggccagcuc cggaccuaca aucgaggaag ucgacugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  4326
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt5)

<400>  4326
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucagcgccu ccagagcugc cgcggcucgg cuggugggcg      120

ccgccgcuuc ucgcgggccc accgccgcua gacaccagga cagcuggaac ggacucuccc      180

augaggccuu ccggcugguc ucucgcagag auuacgcgag cgaagccauu aagggcgcug      240

uuguggggau cgaccuugga acaacgaaua gcugcguggc cgucauggag ggcaaacaag      300

cuaaggugcu ggaaaacgcc gagggggcgc ggaccacacc uucuguugug gccuuuaccg      360

cugauggaga acgccucguc ggcaugccgg ccaaaagaca ggcugugaca aaucccaaca      420

auaccuucua ugccacaaag cggcugauug gccgcagaua cgacgauccu gagguucaga      480

aagacaucaa gaacgugccc uuuaagauug uccgggccag caauggggau gcuugggugg      540

aggcgcacgg aaaacuuuau uccccuagcc agaucggcgc cuucgugcug augaagauga      600

aagaaaccgc ugagaacuac cucgggcaua cggccaagaa ugccgucauc accguucccg      660

cuuauuuuaa cgacucucaa cgccaggcca caaaagaugc gggacagauu uccggccuga      720

augugcugag agugaucaac gaaccuaccg cugccgcccu cgcuuacggg cuggacaaga      780

gcgaggauaa ggucauugcc guguaugacc uuggaggcgg cacauucgau aucucuauuc      840

uggagaucca gaaagggguu uuugaaguga aguccaccaa uggagacacg uuccucggcg      900

gggaggacuu ugaucaagcu cugcuucggc acauugucaa agaguucaag cgcgaaacag      960

gaguggaccu gaccaaagau aacauggccc uccagagagu ucgggaagcg gccgagaagg     1020

cuaaauguga gcuguccucu uccgugcaga cagacaucaa ucugccguac cucaccaugg     1080

auagcuccgg ccccaagcau cugaacauga aacuuaccag agcccaguuu gaagggaucg     1140

ucacagaccu gauucgccgg acgaucgcuc cuugccaaaa ggccaugcag gaugcggagg     1200

ugucuaagag cgacauugga gaagucaucc ucgugggcgg caugaccaga augcccaaag     1260

uucagcaaac agugcaggau cuguucgggc gcgccccuuc caaggcuguc aaccccgacg     1320

aggccguggc uauuggagcc gccauccagg gcgggguucu ugcuggagau gugaccgacg     1380

uccugcuccu ggacgugaca ccgcugagcc ucggcaucga aacccugggc ggcguguuua     1440

cgaaacuuau uaaucggaac acaaccaucc cuaccaagaa gucucagguu uucuccacag     1500

cggccgaugg acaaacccag gucgagauua aaguguguca gggcgagaga gaaauggcug     1560

gggacaauaa gcugcucgga caguucacac ugaucggcau ucccccugcu ccccgcgggg     1620

ugccccaaau cgaggucacg uuugauaucg acgccaacgg aauugugcac guuagcgcca     1680

aagauaaggg caccgggcgg gaacagcaga ucgugauuca gucuagcggc ggacuuucca     1740

aagacgauau cgagaauaug gucaagaacg ccgaaaagua cgcggaggag gacagacgca     1800

aaaaggaacg gguggaggcu guuaauaugg ccgaaggcau uauccacgau acagagacca     1860

aaauggagga guucaaggac caacugccug ccgaugaaug caacaaacuc aaggaagaga     1920

uuucuaagau gagagaacug cuggcucgca aagacagcga gacaggggag aauauccggc     1980

aggccgcguc cagccuccag caggcuucuc ugaaacuuuu ugaaauggcc uauaagaaga     2040

uggccuccga gagagaagga agcgggucuu ccgggaccgg agagcaaaaa gaagaucaga     2100

aggaggagaa acagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  4327
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt5)

<400>  4327
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg aggcuggcgg gagcgaugga cccagagaaa      120

ccgccccuac auccgcguac ucuagcccgg cucggucccu gggcgacacg gggaucacac      180

cccucucucc uagccacauu gugaacgaua ccgacuccaa ugucucugag cagcagagcu      240

uccugguugu gguggccguc gauuuuggaa ccacauccag cggcuaugcc uacucuuuca      300

ccaaagaacc cgagugcauc caugugaugc gcagauggga agggggagac ccuggcguuu      360

ccaaccaaaa gacacccacc acgauucuuc ugaccccuga gcggaaauuu cacagcuucg      420

gcuaugcugc ccgcgauuuu uaccaugacc ucgauccgaa ugaggcuaag caguggcugu      480

aucuugaaaa auucaagaug aagcugcaca caaccgggga ccucacaaug gauaccgacc      540

ugacggccgc gaacggcaaa aaggugaaag cccuggagau cuuugcuuac gcccuccagu      600

auuucaagga acaagcucug aaagagcuuu cugaucaggc cggauccgag uuugaaaaua      660

gcgacgucag augggugauu acaguucccg cgaucuggaa gcagccugcc aagcaguuca      720

ugcggcaagc ugccuaccag gcugggcugg ccucucccga gaacuccgaa cagcucauca      780

uugcccugga gccugaagcu gcgagcaucu acugucgcaa acuuagacug caucagauga      840

uugagcucuc cucuaaggcc gcugugaaug gauauagcgg cuccgacacc gucggggccg      900

gauuuacaca agccaaagag cacauccggc gcaacagaca gagccggacc uuccuggugg      960

aaaaugugau uggcgagauc uggucugaac uggaggaagg cgauaaguac gucguugugg     1020

acuccggggg aggcaccgug gaucucacag uccaccagau ucgccugccc gaggggcauc     1080

uuaaagagcu guauaaggcu acgggaggcc cguacgggag ccucggagug gacuaugaau     1140

uugagaaacu gcuuuacaag aucuucggcg aagauuucau cgagcaauuu aagauuaaaa     1200

gaccugccgc guggguugac cugaugaucg cuuucgaauc ucggaagcgc gccgccgcuc     1260

ccgauagaac caacccucuc aauauuacac ugcccuuuag cuucaucgac uauuacaaaa     1320

aguuucgggg ccacuccgug gagcaugccc ugagaaaauc uaacgucgau uucgugaagu     1380

ggagcuccca ggggaugcuc cgcaugagcc ccgacgcuau gaaugcccug uuuaagccua     1440

ccauugauuc uaucaucgag caccuucggg accuguucca gaaaccggaa guuuccacag     1500

ugaaguuucu cuuccugguc ggaggcuuug cggaggcucc ccuucugcag caagccgugc     1560

aggccgcuuu cggggaccag ugcagaauua ucauuccuca ggaugucgga cucaccaucc     1620

ugaaaggcgc cgugcuguuu gggcucgacc ccgcgguuau uaaggugcgc cggagcccuc     1680

ugacguacgg cgucggagug cuuaacagau auguugaagg caaacauccc ccggagaagc     1740

ugcucgugaa ggaugggaca cgcuggugua ccgacgucuu cgauaaauuc aucucugccg     1800

accaauccgu ggcucuggga gagcugguga agcggagcua caccccugcc aaacccuccc     1860

agcuuguuau cgucauuaau aucuauucua gcgaacacga uaacgugucc uuuauuacag     1920

acccuggcgu gaagaaaugc gggacccuca gacuggaucu gacaggaacg ucuggcaccg     1980

cuguccccgc ccgccgggag auccagacac ucaugcaguu cggggacacc gaaauuaagg     2040

ccacagcuau cgauauugcg accagcaagu ccgugaaagu uggcaucgac uuucugaacu     2100

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  4328
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt5)

<400>  4328
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuggccgugc ccgagauggg ccuccagggg cuguacaucg      120

gaagcucccc ugaaagaucu ccggucccca gcccucccgg cuccccucgg acccaagagu      180

cuugcgggau ugcuccccuu acaccuagcc aguccccgaa gcccgaaguu cgcgccccuc      240

agcaggcguc uuucagcgug guggucgcua ucgacuuugg aacgaccucc agcggcuaug      300

ccuucucuuu ugccuccgau cccgaggcua uucacaugau gagaaaaugg gaagggggag      360

acccuggcgu ggcccaucaa aagacaccca ccugucugcu ccugacaccg gagggcgcuu      420

uccacagcuu uggguacacc gcccgggauu auuaccauga ccuugauccu gaggaagcgc      480

gcgacuggcu guauuucgag aaauuuaaga ugaaaaucca cucugccaca gaucucaccc      540

ugaagacgca gcuggaagcu guuaacggaa agaccaugcc cgcccucgag guguucgcuc      600

augcccugag auuuuuccgg gagcacgcgc uucaggaacu gcgcgagcag uccccuagcc      660

uccccgaaaa agacacaguc agaugggugc ugaccguucc cgccauuugg aagcaaccug      720

cuaaacaguu uaugcgggag gccgcuuacc uugccggccu ggugucucgc gaaaaugccg      780

agcagcuccu gaucgcucug gagccggaag cggccuccgu cuauugcaga aagcuccggc      840

ugcaccagcu ucuggaucuc agcgggcgcg cucccggagg cgggagacug ggagagcggc      900

gcuccaucga cucuagcuuc agacaagccc gggaacagcu uagacgcucc cggcauagca      960

gaacauuucu gguggagucu ggcgugggcg aacucugggc cgagaugcag gcuggggauc     1020

gcuacgucgu ugccgacugu ggaggcggga ccguggaucu gacggugcac caacuggagc     1080

agccucaugg aacacucaaa gaacuguaca aggcguccgg cgggcccuau ggagcugucg     1140

gcguggaccu ugccuucgag cagcugcucu gccggauuuu cggcgaagac uuuaucgcca     1200

ccuucaagag acagcgcccu gcugccuggg uugaucugac aauugcuuuu gaggcccgga     1260

aaagaaccgc ggggccccac cgcgccggag cucuuaacau cagccugccg uucucuuuua     1320

uugacuucua ccggaagcaa agaggccaca auguggaaac cgcccuccgc cggagcuccg     1380

ucaacuuugu gaaauggucu agccagggga ugcugagaau guccugugag gcuaugaaug     1440

agcuguucca gccuacaguu agcggaauca uucagcauau cgaagcccuc cuggcgcggc     1500

ccgaggugca aggcgucaaa cuucuguuuc ucgucggggg cuucgccgaa ucugcugugc     1560

ugcagcacgc cgugcaggcu gcccugggag cccgcggccu uagaguugug gucccucaug     1620

auguggggcu cacgauccug aagggagcug uucuguuugg ccaggcgccc gggguggucc     1680

gggugagacg cuccccucuc accuauggag ugggcguucu gaaccgguuc guccccggga     1740

gacacccgcc ugagaaacuu cuggugcgcg acggcagacg guggugcaca gauguguuug     1800

agcgcuucgu cgccgcugaa caaagcgugg cccucggaga ggaaguuaga cggucuuacu     1860

gucccgcccg ccccggccag agacgggugc ugauuaaucu guauugcugu gcugccgagg     1920

acgcgcgcuu caucaccgau ccugggguca gaaagugcgg agcucuuucc cucgaacugg     1980

agccggccga cuguggccag gauacagccg gggcuccccc uggacggcgc gagauuagag     2040

ccgcgaugca guuuggcgac accgaaauca aggugacggc uguugaugug agcacaaacc     2100

gguccgucag agccucuauu gacuuccuga gcaauugagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  4329
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt5)

<400>  4329
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagagaga ugaccauccu gggcagcgcu gugcucacac      120

ugcuucuggc cggguaccuc gcgcagcaau aucugccccu uccuacgccg aaggucauug      180

gaaucgaccu gggcaccaca uacugcuccg uugggguguu cuuucccgga accggcaaag      240

ugaaggucau uccugaugaa aacgggcaca ucucuauucc cagcauggug uccuucacag      300

acaaugaugu uuauguggga uacgagucug ucgaacucgc ugacagcaac ccucagaaua      360

ccaucuauga ugccaaacgg uuuaucggca agauuuucac agccgaggaa cuggaggcug      420

agaucggccg cuaccccuuu aaagugcuga acaagaaugg gaugguugag uucuccguga      480

ccucuaacga aacgauuacc gucagcccug aauauguggg auccagacuc cugcuuaagc      540

ugaaagagau ggccgaggcu uaccucggca ugccgguggc caaugcgguc aucagcguuc      600

ccgccgaauu ugaccugaag cagcggaacu cuacaauuga ggcugccaau cuugcugggc      660

ugaaaauccu ccgcgugauu aacgaaccua ccgccgcggc cauggcuuac ggacugcaua      720

aggccgaugu guuccacguc cuggugaucg accucggcgg gggaacacug gauguuuccc      780

uucugaauaa acagggcggc auguuucuca ccagagcuau gagcgggaac aauaagcugg      840

gaggccaaga cuucaaccag cggcuucugc aguaucucua caagcagauc uaucaaacgu      900

acggguuugu gcccucucgc aaagaggaaa uucauagacu gcggcaggcc gucgagaugg      960

ugaagcugaa ucucacacug caccaguccg cccagcuuag cguucugcuc accguggagg     1020

aacaagaucg caaagagccu cauucuuccg acacagaacu gcccaaggau aaacuuagcu     1080

ccgcugacga ccacagaguc aacucuggau ucggccgggg gcugagcgau aagaaauccg     1140

gagagagcca ggugcucuuu gaaaccgaga ucucucgcaa gcuguucgac acccugaacg     1200

aggaucucuu ccagaagauu cuggucccga uccaacaggu gcuuaaagaa ggccaccugg     1260

agaagacaga aauugacgag guugugcucg ucggcggguc cacgagaauc ccucggaucc     1320

gccaggugau ucaggaauuu uucggaaaag aucccaauac cagcguugac ccugaucugg     1380

cgguggucac aggcguggcc auccaagcug ggauugacgg aggcucuugg ccccuucagg     1440

ugagcgcccu ggagaucccc aacaagcauc uccagaaaac caauuuuaac ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4330
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt5)

<400>  4330
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgcuaucg gcguccaccu ggggugcacc agcgccugug      120

ucgcgguuua caaggacggc agagcuggag ugguggccaa cgaugccggg gaccggguca      180

cacccgcugu gguugccuau uccgagaaug aagagauugu gggacucgcu gccaaacagu      240

cucgcaucag aaacauuagc aauacgguca ugaaggugaa acaaauccug ggccgguccu      300

cuagcgaucc ucaggcgcag aaguacauug ccgaauccaa augccuuguu aucgagaaga      360

acgggaagcu gcgcuaugaa aucgacaccg gagaggagac aaaauucgug aauccggaag      420

augucgcuag acucaucuuu ucuaagauga aagagaccgc ccauagcgug cugggcuccg      480

acgcuaacga uguggucauu acaguucccu ucgacuuugg cgaaaagcag aaaaaugccc      540

uuggggaggc ggcccgggcu gccggauuca acgugcugcg ccucauucac gagccuagcg      600

cugcccugcu ggccuacggc aucgggcaag auucucccac cggaaagucc aauauucucg      660

uguuuaagcu gggcgggaca agccuuucuc uguccgucau ggaagugaac agcggaaucu      720

auagaguucu cucuaccaau acggacgaua acauuggcgg cgcucauuuc accgagacac      780

uggcgcagua ccuugccucc gaauuucagc ggagcuucaa acacgacgug cgcgggaaug      840

cuagagccau gaugaagcug accaacuccg ccgaggucgc uaaacauucu cucagcacac      900

ugggauccgc caauuguuuu cuggauagcc ucuaugaagg ccaggacuuc gacugcaacg      960

ugucucgggc gcgcuuugag cugcuuuguu ccccucuguu caacaagugc aucgaggcua     1020

ucagagggcu ccuggaucaa aauggauuua ccgccgacga uauuaacaaa guugugcuuu     1080

guggcgggag cucucggauc cccaagcugc agcagcucau uaaagaccug uucccugccg     1140

ucgaacugcu caauagcauc ccgcccgaug aggugauucc uaucggagcu gccaucgaag     1200

cuggcauucu gaucggcaag gagaaccuuc uggucgaaga cucccucaug auugagugcu     1260

cugcccgcga uauccuggug aaggggguug acgagagcgg agcguccaga uucacggugc     1320

uuuuucccag cggcacaccu cugcccgccc ggagacagca cacccuccaa gcuccggggu     1380

cuauuuccag cgucugucug gaacuguacg agucugaugg caaaaauucc gccaaggaag     1440

agacaaaauu cgcucaggug guucuccagg accuggauaa gaaagaaaac ggacuucgcg     1500

acauccuggc cgugcucacc augaagcggg acgggagccu gcacgugacc ugcacagauc     1560

aagagacggg caagugugag gcgaucucca uugaaaucgc cucuugagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  4331
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt5)

<400>  4331
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gccuggacgu ugggucccag ucuugcuaca      120

ucgccguggc uagagccgga ggcauugaga ccaucgcgaa cgaauuuagc gaucggugua      180

cacccuccgu gauuucuuuu gggagcaaga aucgcacgau cggagucgcu gccaaaaacc      240

aacagauuac ccacgccaau aacacagugu ccaauuucaa gagauuucau ggccgggcuu      300

ucaacgaccc uuuuauccag aaagagaagg aaaaucucuc uuaugaucug guuccgcuua      360

aaaacggggg agugggcauc aaggucaugu acaugggcga ggaacaccug uucagcgugg      420

agcagauuac cgccaugcuc cugacaaaac uuaaagagac cgcugaaaau ucccugaaga      480

aacccguuac agacugcgug aucagcgucc cuucuuucuu caccgaugcc gagcgcagau      540

ccgugcucga cgcggcccaa auuguggggc ugaacugucu gcggcucaug aaugauauga      600

cggcugucgc ccugaacuau ggaaucuaca agcaggaccu ucccagccug gaugaaaaac      660

cucgcauugu uguguuugug gacaugggcc auucugcuuu ccaggucucc gccugcgcgu      720

uuaauaaggg gaagcucaaa gugcugggaa ccgccuucga ucccuuucuu ggcgggaaga      780

acuucgacga gaaacugguu gagcacuucu gugcugaauu uaagacaaaa uauaagcucg      840

augccaaaag caagaucaga gcucugcugc ggcucuacca ggagugcgaa aagcugaaaa      900

agcugauguc uuccaauagc accgaccuuc cucucaacau ugaguguuuc augaacgaca      960

aagauguguc cggaaagaug aaucgcucuc aauuugagga acugugcgcc gagcuucugc     1020

agaaaaucga agucccgcuc uauagccugc uggagcagac acaucucaag guggaagacg     1080

uuuccgccgu ggagaucguc ggcggcgcua cccggauucc cgcggugaag gaaagaaucg     1140

ccaaauucuu ugggaaggau auuagcacga cacugaacgc ugacgaggcc gucgcccgcg     1200

gaugugcccu ucagugcgcu auccugucuc cugcguucaa agugagagag uuuuccguua     1260

ccgaugcugu gcccuucccu auuagccuca ucuggaauca cgacucugaa gauacagagg     1320

gcguccacga aguguuuagc cggaaccaug ccgcccccuu cuccaagguu cugaccuuuc     1380

uucgcagagg gccguucgag cuggaggcuu uuuacucuga cccucaagga gugcccuacc     1440

cugaagccaa aaucggccgg uucgucgugc agaaugugag cgcucagaag gauggggaga     1500

aguccagagu uaaagucaag gugcgcguga acacccacgg aauuuucaca aucagcacgg     1560

ccucuauggu cgaaaaagug cccaccgagg aaaaugagau guccagcgag gcggacaugg     1620

aaugucucaa ccaacggccc ccugagaauc cggauacaga caagaacguu cagcaggaca     1680

auucugaagc cggcacccag ccccaagugc agacagaugc ucagcagacc ucccaaagcc     1740

cucccucccc ugagcugacg ucugaagaga acaaaauucc cgacgccgau aaggcuaaug     1800

agaagaaagu cgaccagccg ccugaagcca agaaacccaa gaucaaagug guuaacgugg     1860

agcugccuau ugaagcgaau cucgucuggc agcugggcaa ggaucuucug aacauguaua     1920

ucgagacaga agggaaaaug aucaugcagg acaagcucga gaaggagaga aacgaugcca     1980

aaaaugcugu ggaagaguac guuuaugaau uucgcgacaa gcugugcgga cccuacgaga     2040

aauucauuug cgaacaagau caucagaacu uucugcggcu ucucaccgag accgaggacu     2100

ggcuguauga agagggcgaa gaucaggcca agcaggcuua cguggacaaa cuggaggagc     2160

ucaugaagau cgggacaccu gucaagguga gauuccaaga agccgaggaa cgccccaaaa     2220

uguuugagga acugggacag cggcuucagc acuaugccaa gauugcugcg gauuucagaa     2280

auaaagacga gaaguacaac cacaucgacg agagcgaaau gaaaaaggug gagaaguccg     2340

ucaaugaagu uauggagugg augaacaaug ugaugaacgc ccaagcuaaa aagucucugg     2400

aucaggaccc ggugguccgc gcccaggaaa uuaaaaccaa gaucaaagag cucaauaaca     2460

caugugagcc ugugguuacg cagcccaagc ccaagauuga aagcccuaaa cuggagcgga     2520

ccccgaaugg ccccaacauc gauaagaaag aagaggaccu ggaagauaag aauaacuuug     2580

gggccgagcc uccccaucaa aauggcgagu gcuacccuaa cgaaaagaac uccgugaaua     2640

uggaccuuga uugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  4332
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt5)

<400>  4332
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg ugagacggca gcgccccaga cggcgcgucu      120

gcugggcucu gguugccgug cuccuggcgg aucuucuggc ucucagcgac acccuggccg      180

ugauguccgu cgaucuuggc ucugagagca ugaaaguggc caucguuaag ccuggggugc      240

cgauggaaau cguccugaac aaagagucca gacggaagac acccgugauc guuacgcuca      300

aagaaaauga gcgcuucuuu ggagacucug cugccagcau ggcuauuaag aacccuaagg      360

ccacccugag auacuuccaa caucugcucg gcaaacaggc ggauaauccc cacguggccc      420

uguaucaggc ucgguuuccu gaacacgagc uuacauucga cccccagcgc caaaccgucc      480

auuuucagau cuccucucag cugcaguuca gcccugagga agugcucggg auggugcuga      540

acuacuccag aagccuugcc gaggauuuug cugaacaacc gauuaaggac gccgucauca      600

caguucccgu guucuuuaau caggcggagc ggcgcgccgu gcugcaggcu gccagaaugg      660

cuggacucaa aguccugcag cugaucaacg auaauaccgc cacagcccuc ucuuauggcg      720

uguuccggcg caaggacauu aacaccacgg cucaaaauau cauguuuuac gauauggggu      780

ccggaagcac cguuuguaca auugugaccu aucagauggu caaaacaaag gaggcgggca      840

ugcagccuca acugcagauc agaggcgugg gguucgaccg gacccuugga ggccuggaaa      900

uggagcucag acugcgcgaa cggcuugccg ggcuguuuaa cgagcagaga aagggacagc      960

gcgcuaaaga uguucgggaa aaucccagag ccauggccaa gcuccugcgc gaggcuaacc     1020

ggcugaaaac ggugcucucu gccaaugcgg accacauggc ucaaauugag ggccugaugg     1080

acgaugucga cuucaaggcc aaagugacaa gagucgaguu cgaggaacuu ugcgccgauc     1140

uguuugagcg cgugccuggg cccguucagc aggcucucca guccgccgaa augagccugg     1200

acgagaucga gcaagugauu cuugucggag gcgcuacccg ggugccgaga guucaggaag     1260

ugcugcucaa ggccgucggc aaagaggaac uggggaagaa caucaaugcg gaugaggccg     1320

cugccauggg agcuguguac caggccgcgg cccugucuaa ggcuuucaaa gugaagccuu     1380

uuguuguccg cgacgccgug guguauccca uccucgucga guucacacgg gagguggagg     1440

aagaaccugg cauucauucc cugaaacaca acaagagagu ucuuuuuagc cggauggggc     1500

ccuaccccca gcgcaaagug aucaccuuca acagauacuc ccacgauuuu aauuuccaua     1560

uuaacuaugg agaccugggc uuucucgggc cugaagaucu gcgggucuuc ggaucucaaa     1620

aucugaccac agugaagcuc aagggcguug gcgacagcuu uaaaaaguac ccggauuaug     1680

aguccaaagg gaucaaggcu cacuucaacc ucgacgagag cggagugcug ucucuggaca     1740

gagucgaauc cguguuugag acgcucguug aagauagcgc cgaggaagag ucuacccuga     1800

caaaacuugg caauaccauu agcucccugu ucgggggagg cacaaccccc gacgccaagg     1860

agaacgggac ggauacagug caggaagagg aagagucucc ugcugaaggc agcaaggacg     1920

agcccggaga gcaggucgaa cucaaagagg aagcggaggc cccuguggaa gauggcuccc     1980

agcccccgcc ucccgagccu aagggggacg cuacccccga gggagaaaaa gccaccgaga     2040

aggaaaaugg cgauaaaagc gaggcccaaa agccuucuga gaaggcugaa gccgggcccg     2100

agggaguggc gccggcuccu gaaggcgaga aaaagcagaa acccgcccgc aagcggagaa     2160

uggucgaaga gaucgggguu gagcuggugg ugcuggaccu ucccgaucuc ccugaagaca     2220

aacuggccca guccguccaa aagcugcagg aucucacacu gcgcgaccuu gagaaacagg     2280

aaagagagaa ggcugccaac agccuggaag cguucaucuu ugagacccag gauaagcucu     2340

accaaccgga guaucaggaa gugucuacag aggaacagcg ggaggaaauu uccggcaaac     2400

ugagcgcugc cuccacgugg cuggaggacg agggaguugg cgccaccaca gugaugcuua     2460

aggaaaaacu cgcugagcug cgcaagcugu gucaggggcu uuucuuuaga gucgaagaac     2520

ggaaaaagug gcccgagcgc cugucugccc uugacaaucu gcucaaccau agcuccaugu     2580

uccugaaggg agcuagacug aucccugaaa uggaucaaau uuuuaccgag guggaaauga     2640

caacccuuga gaaaguuauc aaugaaacgu gggccuggaa gaacgcgacc cucgccgagc     2700

aggcuaaacu gcccgccaca gagaagccug ugcugcucuc uaaagacauu gaagcuaaga     2760

ugauggcccu ggaucgggag guccaguacc uucugaauaa ggccaaauuc accaagcccc     2820

gcccuagacc caaagacaag aacggcacac gggcugaacc gccucucaau gcgagcgccu     2880

ccgaucaggg ggagaaagug auucccccug cuggacaaac cgaagacgcc gagcccauca     2940

gcgagccgga aaagguugag acgggcucug aaccugggga uacagagccc cuggaacugg     3000

gcggaccugg cgccgagccc gagcagaagg aacaguccac cgggcaaaaa cgcccccuua     3060

agaacgacga gcugugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4333
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt5)

<400>  4333
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaaa cccagacaca agaccagccc auggaggaag      120

aggaagugga gacguucgcc uuucaggcug agaucgccca gcugaugagc cucauuauca      180

acaccuucua cuccaauaag gaaauuuuuc ugagagagcu uaucucuaac agcuccgaug      240

cgcuggacaa aauucgguau gaaucucuca cagauccgag caagcuggac uccggcaaag      300

agcuucacau caaucugauc cccaacaagc aagaucgcac ccucacaauu gucgacaccg      360

ggaucggaau gacaaaagcu gaucugauua auaaccuggg caccaucgcc aagucuggga      420

cgaaggccuu cauggaggcu cuccaggccg gagcugacau uagcaugauc ggccaguuug      480

ggguuggauu cuacuccgcc uaucuggugg cggaaaaagu gaccgucauu acaaagcaua      540

augaugacga gcaguacgcc ugggaaagcu cugcuggcgg cuccuuuacc gugagaacag      600

auaccgggga gccuauggga cggggcacga aaguuauccu ucaccugaag gaagaccaaa      660

cagaguaucu cgaggaacgc agaaucaaag agauugugaa gaagcauagc caguucaucg      720

gguaccccau uacccuguuu gucgaaaaag agcgggauaa ggaagugucu gacgacgagg      780

ccgaggaaaa agaggauaag gaagaggaaa aagagaagga ggaaaaagag uccgaagaca      840

agccugagau cgaggauguu ggaagcgacg aagaggaaga gaagaaagau ggcgacaaga      900

aaaagaaaaa gaagauuaaa gaaaaguaua ucgaucagga ggagcuuaac aaaacaaagc      960

ccaucuggac ccgcaauccu gacgauauua ccaacgaaga guacggggag uucuacaaau     1020

cucugacaaa ugacugggag gaucaccucg cugugaagca uuuuuccguc gaaggacagc     1080

uggaguucag agcccugcuc uuugugccgc ggcgcgcgcc cuucgaccug uucgagaaca     1140

gaaagaaaaa gaauaacauc aaacuuuaug ugcggcgcgu cuuuauuaug gacaauugcg     1200

aagaacugau cccugaauac cucaacuuca uuagaggcgu uguggauagc gaggaccugc     1260

cccuuaacau cucccgggaa augcugcaac agucuaagau ccucaaagug auucgcaaga     1320

aucuggucaa gaaaugucug gagcucuuua cggagcuggc cgaagauaag gagaacuaua     1380

aaaaguucua cgaacaguuu agcaaaaaua ucaaacuugg cauucacgag gacucccaaa     1440

acagaaagaa gcugagcgag cuccugcggu auuacaccuc ugcuuccggg gaugaaaugg     1500

ugagccuuaa ggacuauugc acaagaauga aagagaauca gaagcacauc uacuacauua     1560

ccggagaaac aaaagaucag guugccaacu cugcuuucgu ggagcgccug cggaagcaug     1620

gccucgaagu caucuauaug auugagccua ucgacgagua cugugugcag caacugaaag     1680

aauuugaggg gaagacccug guuagcguga cgaaggaagg acucgagcug cccgaagaug     1740

aggaggagaa aaagaaacag gaagaaaaga aaacaaaguu cgagaaucuu ugcaagauca     1800

ugaaagacau ucuggaaaag aaagucgaga agguggucgu guccaacaga cucguuaccu     1860

cuccguguug caucgugacc agcacauaug gcuggaccgc caauauggag cgcauuauga     1920

aagcccaggc ucugcgggau aacuccacaa ugggguacau ggcggccaag aagcaccugg     1980

aaaucaaucc ugaccauagc auuaucgaga cgcuuagaca gaaagcugaa gccgauaaga     2040

acgacaaauc ugucaaggac cucgugaucc ugcuguauga gaccgcccuc cuguccagcg     2100

gauuuucucu ugaggauccc caaacacacg cuaaucgcau uuaccggaug aucaaacugg     2160

gccucggcau ugacgaagau gacccuaccg ccgaugacac auccgcggcu guuaccgagg     2220

aaaugccucc ccuggagggg gaugacgaua cgagcagaau ggaagaggug gacugaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  4334
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt5)

<400>  4334
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucca agcuggauuc uggcaaaggg cuccacauca      120

accuggugcc caauaagcag aaccaaaccc uuacaauugu cgacacgaga aucggaauga      180

ccaaaacaga ucugauuaau aaccucggca ccguuacaaa gagcgggacc aaagccuuca      240

uggaggcucu gcaggccgac gcggauaucu ccaugauugg acauuuuggc gugggguucu      300

acucugcuua ucuuguggcc aagaagguca cagugaucag caaacacaau aacgacgaac      360

aguacaccug ggaguccucu gccggaggca gcuuuacggu ucggaccgau gaaugaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  4335
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt5)

<400>  4335
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaag ugcaccaugg cgaggaagag gucgaaaccu      120

ucgccuuuca ggcugagauc gcccaacuga ugagccucau uaucaacaca uucuacucca      180

auaaggagau uuuucugaga gaacuuaucu cuaacgcgag cgacgcucug gauaaaauuc      240

gguaugaguc ccucacggac ccuucuaagc uggauagcgg gaaagaacuu aagaucgaca      300

ucauuccgaa uccccaggag cgcacccuga cacucguuga uaccggaauc ggcaugacaa      360

aagccgaccu gauuaacaau cuggggacca ucgccaaguc cggaacaaag gcuuucaugg      420

aggcccucca ggcuggcgcc gauauuucua ugaucgggca guuuggagug ggcuucuaca      480

gcgcguaucu gguggccgaa aaagucgugg uuauuaccaa gcacaacgac gaugagcaau      540

acgcuuggga auccagcgcc ggcgggucuu uuacggugag agcugaccau ggagagccua      600

ucggccgggg gaccaaaguc auccuucacc ugaaggaaga ucagacagag uaucucgagg      660

aacgcagagu gaaagagguu gugaagaagc auucccaguu cauuggauac cccaucaccc      720

uguaucuuga aaaagagcgg gaaaaggaga uuagcgacga ugaggccgaa gaggaaaaag      780

gcgagaagga agaggaggac aaagacgaug aagagaagcc uaaaaucgaa gacgucgggu      840

cugaugagga ggacgauucc ggaaaggaca agaaaaagaa aacaaagaaa auuaaggaaa      900

aguacaucga ucaggaggaa cugaauaaaa ccaagcccau cuggacgcgc aacccugacg      960

auauuacaca agaggaauac ggcgaguuuu auaaaagccu caccaaugac ugggaggauc     1020

accuggcggu gaagcacuuc ucuguggaag gccagcugga guuuagagcc cuccuguuca     1080

ucccgcggcg cgcucccuuu gaccuuuucg aaaacaaaaa gaagaaaaau aacauuaagc     1140

uguacgucag acggguuuuc aucauggacu ccugcgauga gcucauuccu gaauaucuga     1200

auuuuauccg cgggguggug gacagcgagg aucuuccccu gaacaucucc agagagaugc     1260

uccagcaguc uaaaauucug aaggucaucc ggaaaaauau ugugaagaag ugucuggaac     1320

ucuucagcga gcuggccgaa gacaaagaga acuacaagaa auuuuaugag gcuuucucca     1380

agaaccuuaa acugggaauc caugaggaua gcacaaaucg cagacggcuc ucugagcugc     1440

uuagauacca caccucccaa agcggcgacg aaaugaccuc ucugagcgag uauguuuccc     1500

gcaugaagga aacacagaaa ucuauuuacu acaucacggg ggagagcaag gaacaggugg     1560

ccaacuccgc cuuugucgaa cgggugagaa agcgcggauu cgagguugug uauaugaccg     1620

aaccuauuga ugaguacugc guccaacagc ucaaagaauu ugacggcaag agccuggugu     1680

cugucacaaa agaggggcug gagcuccccg aagaugagga agagaagaaa aagauggaag     1740

aguccaaggc uaaauucgag aaucugugua aacuuaugaa ggaaauccug gacaagaaag     1800

uggagaaggu uaccaucagc aaccggcucg ugucuucccc gugcuguauu gucacaagca     1860

ccuauggaug gacggcgaau auggaaagaa ucaugaaggc ccaggcucug cgcgauaacu     1920

ccacaauggg cuacaugaug gccaaaaagc aucuggagau uaauccugac caccccaucg     1980

uggaaacccu ucggcagaaa gccgaggcug auaagaacga caaagccguu aaggaccucg     2040

ugguccugcu guuugagacc gcgcuccugu cuagcggcuu cucccuugaa gauccucaaa     2100

cacacucuaa uagaauuuau cgcaugauca agcuggggcu cggaaucgac gaggaugaag     2160

uggcugccga ggagcccaac gccgcugugc ccgacgaaau uccuccgcug gagggcgaug     2220

aagacgccag ccggauggag gaaguugauu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  4336
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt5)

<400>  4336
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agagcccugu gggugcucgg ccugugcugu guccuucuga      120

ccuucgggag cguucgggcu gacgaugagg uggacgugga uggaacaguc gaagaggacc      180

ucggcaaguc ccgcgaaggg ucuagaacgg augacgaggu gguucagcgg gaagaggagg      240

ccauccaacu ggauggacuu aacgcgagcc agauucgcga acugagagag aaauccgaaa      300

aguuugcuuu ccaggccgag gugaaucgga ugaugaaacu caucauuaac ucucuguaca      360

agaauaaaga gaucuuucug cgcgaacuca uuagcaacgc cuccgacgcu cuggauaaga      420

ucagacuuau cucucugacc gacgagaaug cccucagcgg caacgaagaa cugacaguca      480

agauuaaaug cgauaaggag aaaaaucuuc ugcacgugac cgacacaggg guuggaauga      540

cccgggagga gcucgugaag aaccugggca caaucgcuaa auccggcacc agcgaguucc      600

ugaauaagau gacggaggcc caggaagaug ggcaaucuac cuccgagcuc auuggacagu      660

uuggcgucgg guucuauagc gcguuucugg uggccgacaa ggugaucguc acaucuaaac      720

auaacaauga cacccagcac auuugggaau ccgauagcaa cgaguucucu guuaucgcug      780

acccccgcgg aaauacacuu ggcagaggga ccacgauuac acuggugcuc aaggaggaag      840

ccuccgauua ccuggagcuu gacaccauca aaaaccuggu gaagaaauau agccaguuua      900

ucaauuuccc uauuuacguc ugguccucua agacagaaac cguggaggaa ccgauggagg      960

aggaagaggc ugccaaagaa gagaaggagg aaagcgauga cgaggcggcc guugaagagg     1020

aagaggagga aaagaaaccc aagaccaaaa agguggagaa aacagucugg gauugggaac     1080

ucaugaacga caucaagccu auuuggcaac ggcccuccaa ggagguggaa gaggaugagu     1140

auaaagccuu uuacaagagc uucucuaaag aauccgacga uccuauggcu uauauccauu     1200

uuacggcuga gggagaaguu accuucaaga gcauucuguu cgugcccaca ucugccccuc     1260

gcggccuguu ugacgaguac ggcagcaaaa aguccgacua caucaagcuc uaugucagac     1320

ggguguucau caccgaugac uuucacgaua ugaugccgaa auaccugaac uucgucaagg     1380

gggugguuga cucugaugac cuuccccuga augugagccg cgaaacacuc cagcagcaua     1440

aacugcuuaa ggucauucgg aaaaagcugg ugagaaagac ccucgauaug aucaaaaaga     1500

uugccgacga uaaauauaac gacacguuuu ggaaggaguu cggaacaaau aucaaacugg     1560

gcguuauuga ggaucacucc aacagaaccc gccuggcuaa gcuccugcgg uuucagagcu     1620

cucaccaucc uaccgacauc acaucccuug aucaauacgu ggaaagaaug aaagagaagc     1680

aggacaagau cuauuucaug gcggggagcu cucgcaaaga agccgagucc agccccuuug     1740

ucgagcggcu gcucaagaaa ggauacgaag ugauuuaucu gaccgagccu guggacgaau     1800

acuguaucca ggcucugccc gaguucgaug gcaagagauu ucaaaauguu gccaaagaag     1860

gggucaaguu cgacgagucc gagaagacaa aagaaucucg cgaggccgug gaaaaggagu     1920

uugaaccgcu ucucaacugg augaaagaua aggcucugaa agacaagauu gagaaggccg     1980

uggucagcca gcggcugacg gaguccccuu gcgcgcucgu ggcuucucag uacggaugga     2040

gcggcaauau ggaaagaauc augaaagccc aggccuauca aaccggcaag gauauuucca     2100

caaacuacua ugcuagccag aaaaagaccu ucgagaucaa uccccgccac ccucugauuc     2160

gggacaugcu uagacgcauc aaagaagaug aggacgauaa gacaguucug gaccucgccg     2220

ugguccuguu cgaaaccgcu acgcugcggu cuggguaccu ucuccccgau accaaggccu     2280

auggagacag aaucgagcgg augcugcgcc ugucccucaa cauugauccc gacgcgaaag     2340

uggaggaaga accugaagag gagccggaag agacagccga agacaccaca gaggauaccg     2400

aacaggacga ggaugaggaa auggacguug gcacggauga ggaagaggaa acagcuaagg     2460

agagcaccgc cgagaaagac gaacugugag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  4337
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt5)

<400>  4337
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagagagc ugcgggcucu ccugcuuugg ggccgcagac      120

ugcggccccu ccugcgcgcc ccugcgcuug cugccgugcc cgggggaaag ccgauccugu      180

gcccuagacg gaccacagcc cagcucggcc cccgcagaaa cccugcuugg agccugcaag      240

ccgggcggcu guucuccacg cagaccgcug aagacaaaga ggaaccccuc cacucuauua      300

ucagcuccac agagucuguc cagggaagca ccuccaagca ugaauuucag gccgagacaa      360

agaagcugcu ugauauuguu gcgcgcucuc uguacagcga gaaagaagug uucaucagag      420

agcucauuuc caaugccagc gacgcucugg aaaaacuucg gcacaagcug gugucugaug      480

gccaagcccu cccugagaug gagauccauc ugcagaccaa cgcugaaaaa gggacaauca      540

ccauucagga cacgggaauc ggcaugaccc aggaggaacu ggucuccaau cucggcacaa      600

uugcccgcag cgggucuaag gcguuucugg augcccuuca aaaccaggcu gaggccucca      660

gcaaaaucau uggacaguuc ggcguggggu uuuauucugc uuucaugguu gccgacagag      720

uggaagucua cucccggagc gccgcuccgg gaucccuggg cuaucagugg cucucugaug      780

ggagcggagu guuugagauc gcggaggccu ccggcguucg caccggcaca aagauuauca      840

uccaccugaa aagcgacugu aaggaguucu cuuccgaggc uagagugcgg gaugucguga      900

ccaaguacag caauuuugug ucuuuccccc uuuaucugaa cgggagacgc augaauacgc      960

uccaagccau uuggaugaug gacccuaaag auguccggga auggcagcau gaggaauuuu     1020

acagauaugu ugcccaggcu cacgacaagc cccgcuacac acugcacuac aaaaccgaug     1080

ccccucugaa cauccggagc auuuucuaug ugcccgacau gaagccgucc auguuugacg     1140

ugucuagaga gcucggaagc uccgucgcgc uguacagccg caaagugcuu auccaaacaa     1200

aggcuaccga uauucugccu aaauggcucc gguucaucag aggcguugug gacucugagg     1260

auaucccccu gaaucuuucc cgcgaacugc uccaggagag cgcccugauu cggaagcuga     1320

gagacguccu ccagcagcgc cugaucaagu ucuuuauuga ucaaucuaaa aaggacgccg     1380

aaaaauaugc uaaguucuuu gaggauuacg ggcuuuucau gcgggaagga aucgugaccg     1440

ccacagagca ggagguuaaa gaagacauug cuaagcugcu cagauaugag uccagcgccc     1500

ugccuuccgg ccagcugacg ucucuuagcg aauacgcguc ccggaugcgc gccgggacca     1560

gaaacaucua uuaccucugc gcucccaauc ggcaucuggc cgagcacucu cccuacuaug     1620

aggcuaugaa gaaaaaggau acagaagugc uguuuuguuu cgagcaguuu gacgaacuca     1680

cccugcuuca ucugagagag uucgauaaaa agaaacucau cagcgucgaa acagacauug     1740

uggucgacca cuacaaggag gagaaguuug aagaucgcuc cccugccgcg gagugccuga     1800

gcgaaaaaga gaccgaagaa cugauggccu ggaugcggaa cgugcuugga ucuagaguua     1860

cgaaugugaa ggucacacuc cgccuggaca cccacccggc uauggugacc guucuggaga     1920

ugggcgccgc uagacauuuc cuccggaugc aacagcuggc caaaacacag gaggaacgcg     1980

cccagcuucu gcaacccacc cucgaaauca acccuagaca cgcucugauu aagaaacuga     2040

aucagcuucg ggcguccgag cccggccucg cccagcugcu gguggaucag aucuaugaaa     2100

acgcuaugau ugccgccggg cucgucgacg auccucgcgc uaugguggga agacugaacg     2160

agcuucuggu gaaggcccuc gagcggcauu gaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  4338
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt5)

<400>  4338
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagauca gcucccugcc cacccagcuu uucaaaugcu      120

guuuuugcga cuuccugaag gugaaaaugc acacaauguc uagcucccau cucuuuuacc      180

uggcccucug ucugcuuacg uucaccucua gcgcuacagc cgggccugag acccugugcg      240

gagcggaacu cgucgaugcu cugcaauuug uuuguggcga cagaggguuc uauuuuaaca      300

agccgacagg auacggcucc ucuagccggc gcgcucccca gaccgggauu guggaugagu      360

gcuguuucag auccugcgac cugcggcgcc ucgaaaugua uugugccccu cugaaacccg      420

ccaagagcgc cagaucugug cgggcucagc gccacacaga uaugccuaag acccagaaag      480

agguccaucu uaagaaugcc uccagaggaa gcgcgggcaa caaaaauuac cggaugugag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  4339
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt5)

<400>  4339
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca ugggaaagag caugcuggug cuccugaccu      120

uccuugccuu ugcuuccugc uguauugccg cguacagacc uucugagaca cugugcgggg      180

gcgaacucgu cgacacgcug caguucguuu guggggaucg gggauuuuau uucagccgcc      240

cggcuuccag agugucucgg cgcagcagag gcaucgugga ggaaugcugu uuucgguccu      300

gcgaccuugc ccugcucgag accuacugug ccacacccgc uaaaucugaa cgcgauguca      360

gcaccccucc cacagugcug ccugacaacu uccccagaua uccuguuggg aaguuuuucc      420

aauacgauac cuggaaacag uccacacagc ggcugcgcag aggacucccg gcccugcuuc      480

gggcucgcag aggccacgug cuggccaagg agcucgaggc guuucgggaa gccaaacgcc      540

auagaccccu gauugcccuu ccuacccagg accccgcuca cggcggggcu ccucccgaga      600

uggccagcaa ucggaaguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  4340
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt5)

<400>  4340
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagcuucu ccaccucugc cuuuggcccc guggcuuuca      120

gccuggggcu ccugcuuguc cugccugccg cguuuccggc ucccguuccu cccggagagg      180

acuccaagga uguggccgcc ccucacagac agccccucac aucuagcgaa cggaucgaca      240

aacaaauucg cuacauccug gauggcauuu ccgcucuuag aaaggagacg ugcaauaaau      300

cuaacaugug ugaaagcucc aaggaggccc uggcugaaaa uaaccucaau cugccuaaaa      360

uggccgagaa ggacgggugc uuccagagcg gauuuaacga ggaaaccugu cuggugaaga      420

ucauuacagg ccuccuggag uucgaagucu aucuugagua ccugcagaau cgguuugagu      480

cuuccgaaga acaggcgcgc gccgugcaaa ugagcaccaa aguucucauc caguuccugc      540

agaagaaagc uaagaaccuu gaugccauca caaccccgga ccccacaacc aaugcuucuc      600

ugcucacgaa acugcaggcc caaaaccagu ggcugcagga uaugaccaca caucucauuc      660

ugagauccuu uaaggaguuc cuucagagcu cucugcgggc gcuccgccaa augugaggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  4341
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt5)

<400>  4341
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcucu ggcugagagg cuuccuucug gccagcugcu      120

ggaucauugu gcgguccucu ccuaccccgg ggagcgaggg acacuccgcu gcccccgacu      180

guccuucuug cgcgcucgcu gcccugccca aggauguccc uaacagccag cccgaaaugg      240

uugaggccgu gaaaaagcau auccuuaaua ugcugcaccu caaaaagcgc ccugacguga      300

cacaaccggu ccccaaagcu gcccugcuga acgcuauuag aaagcuccau gugggcaagg      360

uuggggaaaa uggauacgug gagaucgaag augacauugg ccggcgcgcc gagaugaacg      420

agcugaugga acagacgucc gagaucauca ccuuugcgga aucugggaca gccagaaaaa      480

cccuucacuu cgagauuagc aaggagggau ccgaucugag cgucguggaa cgggcugagg      540

uuuggcucuu ucugaaagug ccuaaggcca aucgcacaag aaccaaaguc acaauccggc      600

uuuuccagca gcaaaagcau ccccagggcu cucuggacac cggcgaagag gcugaagagg      660

uggggcucaa gggagagcgc uccgaacugc ugcucagcga gaaagugguc gaugccagaa      720

agucuacgug gcacguuuuu ccugugucca gcucuauuca gcggcugcuu gaccagggca      780

aauccagccu ggaugugcgc aucgcgugug aacaaugcca ggaguccggg gccucucucg      840

uccugcuugg aaagaaaaag aaaaaggaag aggagggcga agggaagaaa aagggaggcg      900

gcgaaggggg agcuggcgcc gacgaggaga aagaacagag ccacagaccc uuccugaugc      960

uccaggcucg gcaauccgag gaucauccgc accgcagacg gagacgcggg cuggagugug     1020

acggaaaggu gaacauuugc uguaaaaagc aguuuuucgu uagcuuuaag gauaucggcu     1080

ggaaugacug gauuaucgcc ccuucugggu aucaugccaa cuacugcgaa ggagaguguc     1140

ccucccacau cgcuggcacc agcggcucua gccuguccuu ccacucuaca gugauuaauc     1200

auuaucggau gagagggcac agcccuuuug cgaaccucaa auccugcugu guccccacca     1260

agcugcgccc caugagcaug cuuuacuaug acgauggaca gaauaucauu aaaaaggaca     1320

uccaaaacau gauuguggaa gagugcggcu gcucuugagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  4342
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt5)

<400>  4342
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccugc ccgggagagc ccucggagcu gccugccugc      120

uucugcucgc ggcuggcugg cuggggccug aggccugggg aagcccgaca cccccuccca      180

ccccugccgc ucccccuccg cccccucccc cuggcucccc cgggggaucu caggauacgu      240

guaccagcug cggcggcuuc cggcgcccgg aggaacuugg gagaguggac ggagauuuuc      300

uggaagccgu caagcggcac auccucuccc gccugcaaau gagaggccgg ccuaacauua      360

cacaugcugu ucccaaagcc gcgaugguga ccgcccugcg caagcuccac gcugggaaag      420

ugagagagga cggacggguc gaaaucccuc aucuggaugg ccacgccucu cccggggcug      480

acggacagga gcgcgugagc gagauuaucu ccuucgccga aacagauggc cuugcgucua      540

gcagaguucg gcuguacuuu uucauuucca augagggcaa ccagaaucuc uuuguggucc      600

aggccagccu guggcuuuau cugaagcucc ugcccuacgu gcuggaaaaa gggucucgca      660

gaaagguucg ggugaagguc uauuuccaag agcagggaca uggcgaccgc uggaacaugg      720

uggagaaaag aguggaucuc aagcgguccg gguggcacac cuuuccucug acagaagcua      780

uccaggcccu uuucgagaga ggagaacgcc ggcugaaucu cgacguccag ugugauagcu      840

gccaagagcu ggcuguugug ccgguguuug ucgaccccgg cgaagagucu cacagaccuu      900

ucgugguugu gcaggcccgc cuuggggauu cccggcauag aauccgcaaa cggggacugg      960

agugugacgg cagaaccaac cucugcuguc gccagcaguu uuucauugac uuucggcuga     1020

ucggcuggaa ugauuggauu aucgccccca cgggguacua uggaaacuac ugcgaaggca     1080

gcuguccugc uuaucuggcg gggguccccg gaucugccuc cagcuuccac accgcugugg     1140

uuaaucaaua cagaaugcgc ggccucaacc cggggacagu caauuccugc uguauuccua     1200

ccaagcuguc uacaaugagc augcuuuacu ucgacgauga guauaacauc gugaaacggg     1260

acgugcccaa uaugauuguc gaagagugcg gcugcgccug aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  4343
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt5)

<400>  4343
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagag ugcuccugcu uaccgcucug acacucugcc      120

acggcuucaa ccuggacacg gagaaugcca ugaccuuuca ggaaaacgcg cggggguucg      180

gacaaagcgu gguucagcuu cagggcuccc gcgugguggu cggggcuccc caggagaucg      240

uggccgccaa ucaaagagga ucucuguacc agugugauua uagcacaggc uccugcgaac      300

cuauucggcu ccagguuccg guggaggcug ucaacauguc ucuggggcug agccucgccg      360

cuaccacauc cccuccucag cugcuugccu guggacccac cgugcaucaa acaugcucug      420

aaaauaccua cguuaagggc cuguguuuuc ucuucggcag caaccugcgc cagcagccuc      480

agaaauuucc cgaggcgcuu agagggugcc cucaagagga cuccgauauc gccuuccuga      540

uugacggaag cggcucuauc auuccgcacg auuuucggcg caugaaggag uucgugucca      600

cggucaugga acagcucaaa aagagcaaaa cccuguuuuc ucugaugcag uauuccgaag      660

aguucagaau ccauuuuaca uucaaggagu uucaaaauaa ccccaauccu cggagccucg      720

ugaagcccau cacccagcug cuugggcgca cacacaccgc uacgggaauu agaaaagugg      780

uccgggaacu guucaacauc acaaauggcg cccgcaagaa cgcuuucaaa auucucguug      840

ugaucaccga cggggagaag uuuggagauc cucugggcua cgaagacgug auucccgagg      900

ccgauagaga aggcgucauc cgguauguga uugggguugg agacgcguuc cgcucugaga      960

aauccagaca ggagcuuaau acaaucgcca gcaagccgcc ucgggaucau guguuucagg     1020

ucaacaauuu cgaagcucug aagaccaucc aaaaccagcu cagagagaaa auuuuugcca     1080

ucgaaggcac ccagacaggg uccucuagcu ccuucgagca cgaaaugagc caggagggau     1140

uuucugcugc cauuacgucc aacggccccc ugcugagcac cguggggucu uacgacuggg     1200

ccggaggcgu uuuccucuau acaagcaagg agaaauccac cuuuaucaau augacacgcg     1260

uggauucuga caugaacgac gcuuaccugg gcuacgcggc cgcuauuauc cuucggaaua     1320

gaguccaaag ccuggugcuc ggggccccuc gcuaucagca caucggacug gucgccaugu     1380

uccggcagaa caccggcaug ugggaaucca augcuaacgu gaaggggacg cagauuggag     1440

ccuacuuugg cgcgagccuu uguucuguug auguggacuc caaugggagc acagaucugg     1500

uccucaucgg cgcuccccau uauuacgagc aaaccagagg aggccaggug ucuguuugcc     1560

cccugccucg cgggcgggcc agauggcagu gugacgccgu gcuguaugga gaacagggcc     1620

aaccgugggg gcgcuucgga gcugcccuca ccguccuggg cgaugugaac ggggacaaac     1680

uuacagaugu ggcuauuggc gcccccggag aggaagacaa ucggggcgcg guuuaccugu     1740

uucacgggac cuccggaagc ggcaucuccc cuucucauag ccagagaauu gccgggucca     1800

agcucucucc ccgccugcag uauuucggac aaagccuguc cggcgggcag gaucuuacaa     1860

uggacggccu cgucgaucug acggugggag cucagggcca cgugcugcuc cugcggagcc     1920

agccuguccu uagagugaaa gccaucaugg aguucaaccc ccgggagguu gcucgcaaug     1980

uguuugaaug caacgaccaa gucgugaagg ggaaggaggc cggagaaguu agaguguguc     2040

ugcacgucca gaaaucuacc cgggacagac uccgcgaggg ccagauccag uccgugguua     2100

cauacgaucu ggcgcuggac agcgggcggc cgcauucuag agccguguuc aaugagacca     2160

agaacuccac acgcagacaa acccaggucc uuggacucac gcagaccugc gaaacacuga     2220

aacugcagcu cccuaauugc auugaggauc ccgugagccc uaucgugcug cggcuuaacu     2280

uuucucuggu cggcacaccc cucagcgcuu ucgggaaccu gcgcccuguu cuggccgaag     2340

acgcucaaag acuuuuuacc gcccucuucc ccuuugagaa gaauuguggc aacgauaaua     2400

uuugccagga cgaucugucc aucaccuuca gcuuuauguc ucuggacugu cucguggugg     2460

gaggcccgcg ggaguucaac gucacgguga caguucgcaa ugauggggaa gacuccuaca     2520

gaacccaggu gacauuuuuc uuuccucugg aucuuagcua ucggaaaguc uccacccugc     2580

aaaaccagcg cucucagaga agcuggcggc ucgccugcga guccgcuucu agcaccgaag     2640

uguccggagc gcugaagucu acaagcuguu ccauuaauca ccccaucuuc cccgagaaca     2700

gcgaaguuac guucaauauu accuuugacg uggauucuaa ggccucccug ggcaacaaac     2760

uucuccugaa ggcuaauguc acaagcgaga acaauaugcc ucgcaccaac aaaacagagu     2820

uccagcugga acucccggug aaguacgccg uuuauauggu ggucaccucu cauggggugu     2880

ccacgaaaua ccugaauuuu acagccagcg agaacaccuc uagagugaug caacaccagu     2940

aucaggucuc caaccuugga cagcggagcc ugcccaucuc ccucguuuuc cuggugccug     3000

ugagacugaa ucaaaccguc aucugggacc gcccccaggu gacauuuagc gaaaaccuuu     3060

cuagcacaug ccauaccaag gagcggcugc cuucccacuc ugacuuccuc gcugaacuga     3120

gaaaggcccc cguugugaau uguagcauug cggucugcca gcgcauccag ugugauauuc     3180

ccuuuuucgg cauccaagag gaauuuaacg cuacgcucaa aggcaaucug uccuucgacu     3240

gguacauuaa gaccucucac aaccaucuuc ugaucgugag cacagccgag auccucuuua     3300

augauuccgu uuucacccug cugcccgggc agggagccuu cgugcggucu cagacagaga     3360

ccaaagucga accguuugag gugccuaacc cccuuccucu gauugucggc agcuccgucg     3420

ggggacuccu gcuccuggcu cuuaucacgg ccgcgcugua uaagcucggc uucuuuaaaa     3480

gacaguacaa ggacaugaug agcgaagggg gacccccggg cgcugagccu caaugaggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  4344
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt5)

<400>  4344
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucagccuga agacccuccc cuuucugcuu cugcuccacg      120

ugcagaucuc caaagccuuc ccugucucua gcaaggagaa aaacacaaag acgguucaag      180

acuaccugga aaaauuuuau cagcuuccgu ccaaucagua ccagucuacc agaaagaacg      240

gcacaaaugu gauuguggag aagcugaaag aaaugcaacg guucuuuggg cucaacguca      300

ccggaaagcc caaugaggaa acacuggaua ugaugaaaaa gccucgcugc ggcgugcccg      360

acagcggggg auucaugcug accccuggca accccaaaug ggagagaaca aaucucaccu      420

aucggauccg caacuacacg ccucagcugu ccgaggcuga aguugagaga gccauuaagg      480

augcguuuga acuuuggucu guggcuagcc cgcugaucuu cacccggauu ucccaggggg      540

aggccgacau caauaucgcc uuuuaucagc gcgaucaugg agacaacagc cccuucgaug      600

gcccuaaugg cauucucgcu cacgccuuuc aacccgggca gggaaucggc ggggacgcuc      660

auuucgaugc cgaggaaaca uggaccaaca caucugcgaa uuacaaccug uuucuugucg      720

ccgcucacga guucggacau ucccugggcc ucgcccacag cucugacccu ggggcucuga      780

uguaucccaa uuacgccuuc agagaaaccu ccaacuacag ccugccgcag gaugacauug      840

auggaaucca ggcgauuuau ggccucucuu ccaacccuau ccaacccacg ggcccuagca      900

cacccaagcc cugugacccu ucccugaccu uugacgccau uacaacccuu cggggagaga      960

uccuguucuu uaaagaucgc uacuucugga gacggcaccc gcagcuccag cgcguggaaa     1020

ugaauuuuau cucucuguuc uggcccagcc uuccuaccgg gauucaagcu gccuaugagg     1080

acuuugauag agaccugauc uuccucuuua agggcaacca guacugggcu cuguccgggu     1140

augauauucu gcagggauac cccaaagaca ucagcaauua uggcuucccu ucuuccguuc     1200

aggccauuga ugccgcugug uuuuaccgga gcaagacaua cuucuuuguc aacgaccaau     1260

ucuggcgcua ugauaaucag agacaguuca uggagcccgg guacccgaaa ucuaucagcg     1320

gagcguuucc uggcaucgaa uccaaggugg acgccguguu ccagcaagag cacuuuuucc     1380

augucuuuuc uggcccccgg uauuacgcuu ucgaucucau ugcccagaga guuacgcgcg     1440

uggcccgggg gaacaaaugg cugaauugca gauauggaug aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  4345
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt5)

<400>  4345
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguggc agccccucgu gcugguccuu cugguucucg      120

gcugcuguuu cgccgcuccu agacaacggc aguccacccu ggugcuuuuu ccgggggacc      180

ugcgcacaaa ccucacggau agacagcugg ccgaggaaua ccuguaucgg uacggauaua      240

cccgcguggc ggagaugaga ggcgaaucua aaagccucgg gcccgcucug cuucugcucc      300

agaaacaacu gucccuuccu gagacaggag aacuggacuc ugccacccuc aaggccaugc      360

ggacaccccg cugcggcguc ccugaucugg ggagauucca gaccuuugag ggagaccuga      420

aauggcacca ucacaauauc acauacugga uucagaacua uagcgaggau cucccccggg      480

cugugaucga cgaugccuuc gcucgcgccu uugcgcugug guccgccguu accccucuua      540

cguucaccag aguguacucu cgggacgcug auauugucau ccaguuuggc guggccgaac      600

auggcgacgg guauccguuc gauggaaagg acggccugcu cgcucacgcc uuucccccug      660

ggcccgggau ucaaggcgau gcgcauuucg acgacgauga gcuguggagc cuugggaaag      720

gaguuguggu cccuacacgc uuuggcaaug ccgacggcgc ugccugucac uuccccuuua      780

ucuucgaagg gagauccuac agcgcuugca ccacagaugg acggucugac ggccugccgu      840

gguguuccac cacggccaac uacgauacag acgaucgcuu cggguuuugc ccuagcgaga      900

gacucuauac ccaggacgga aaugccgaug gcaagcccug ucaguucccu uuuaucuucc      960

aggggcaauc uuacuccgcu ugcacaaccg acggacggag cgauggcuau agauggugug     1020

cgaccacagc caacuacgac cgcgacaagc uguuuggcuu cugccccacg cgggcugauu     1080

cuaccgugau gggaggaaau uccgccggcg agcugugugu guuucccuuc acauuucucg     1140

ggaaagaaua uagcacaugc accuccgagg gaagaggcga cgggcgccug uggugcgcca     1200

ccacgucuaa cuucgauagc gacaagaaau ggggcuuuug uccugaucag ggauacuccc     1260

uuuuccuggu cgcugcccac gaauuuggcc augcgcucgg gcuggaccac agcucuguuc     1320

cggaggcucu uauguauccc auguaccggu ucacagaagg accuccccug cauaaggaug     1380

acgugaaugg cauuagacac cucuacgggc cucgccccga gccggagccu cggcccccua     1440

ccaccacaac accccagccu accgcgcccc cgacggugug cccuaccgga ccucccacag     1500

uccaccccuc cgaaagaccg accgccggcc ccacagggcc ucccagcgcu ggcccuaccg     1560

gacccccuac ggccggcccc ucuaccgcua caaccgugcc gcugagcccu guugaugacg     1620

ccuguaacgu gaauaucuuc gaugcgauug ccgagaucgg gaaccaacug uaucucuuua     1680

aagacggaaa guacuggcgc uucuccgaag gccggggguc uagaccccag ggaccuuuuc     1740

ugauugcuga uaaguggccc gcccuuccgc gcaaacugga cagcgucuuc gaggaacggc     1800

ucuccaagaa acuguuuuuc uuuagcggca gacaggugug gguuuauaca ggggcuucug     1860

ugcugggccc ucggcgccuu gacaagcucg gacugggcgc cgaugucgcc caggugaccg     1920

gggcccugag auccggacgg ggcaaaaugc uccuguucag cgggagacgc cuuuggcggu     1980

uugacgucaa ggcucaaaug guggauccca gaucugccuc cgagguugac cgcauguucc     2040

cuggagugcc ccuggauacg caugacgucu uucaguacag agagaaggcu uauuucugcc     2100

aggaucgguu uuacuggcgc gugagcucca gaucugaacu caaucagguu gaccaagugg     2160

gcuaugucac auacgauauc cugcaguguc ccgaggacug aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  4346
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt5)

<400>  4346
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg ugcuggccgc uuuccucuuu cugagcugga      120

cccauugcag agcccuuccu cugccguccg ggggagacga ggaugaccuc ucugaagagg      180

aucugcaguu cgcggaacgg uaccuucgca gcuauuacca ccccacaaac cuggcuggca      240

uccucaagga gaaugccgcc uccucuauga cggaaagacu gcgggagaug cagagcuuuu      300

ucgggcugga ggucaccgga aaacucgacg auaacacacu ggacguuaug aagaaaccuc      360

gcuguggcgu gcccgaugug ggggaauaua augucuuucc uagaacccuu aaguggucca      420

aaaugaaccu gacauaccgg auugugaauu auacccccga caugacacau ucugagguug      480

aaaaggcuuu caagaaagcc uuuaaggugu ggagcgaugu caccccucuc aacuucacgc      540

gccugcacga cggaaucgcu gauauuauga ucuccuuugg cauuaaagag cauggcgacu      600

ucuacccguu ugaugggccc agcggacuuc uggcccacgc guucccuccc ggcccuaauu      660

augggggaga cgcccacuuu gacgaugacg agaccuggac aucuuccagc aagggcuaca      720

accucuuccu gguggcugcc caugaguucg ggcacucucu gggacucgau cauuccaaag      780

accccggcgc ucugauguuu ccgaucuaca ccuauacagg caagagccac uucaugcuuc      840

cugaugacga uguucaaggg auccagucuc uguacggacc cggcgacgag gauccuaauc      900

ccaagcaccc caaaaccccu gacaagugcg auccgucccu cagccuggac gccauuacgu      960

cccuuagagg ggaaacaaug aucuuuaaag accgguucuu uuggcgccug cauccccagc     1020

aaguggaugc ggaacucuuc cugaccaagu cuuuuuggcc ugaacugccc aacagaauug     1080

acgccgcuua ugagcacccu agccaugauc ucaucuucau uuuucgggga cgcaaauucu     1140

gggcccugaa uggcuacgac auccuugagg gguaucccaa gaaaauuucc gaacugggac     1200

ucccgaagga ggucaagaaa aucagcgcug ccgugcacuu ugaagauaca ggcaagaccc     1260

ugcuuuucuc uggcaaccag guguggagau acgacgauac caaucauauc auggacaaag     1320

auuauccucg gcugauugag gaagacuuuc ccgggaucgg agauaagguc gacgccguuu     1380

acgagaaaaa cggcuacauu uauuucuuca augggccuau ccaguuugag uacuccauuu     1440

ggagcaaccg caucgugaga gugaugcccg cuaacucuau ccucuggugu ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4347
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt5)

<400>  4347
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acacaacgga agacuacgau accacaaccg      120

aguucgacua uggcgaugcc acaccuugcc agaaggugaa ugaaagagcu uuuggggccc      180

aacugcuccc gccccuguac agccuugucu ucguuaucgg acuggugggc aacauucucg      240

ugguccuggu gcuuguucag uauaaacggc ugaagaauau gaccuccauc uaccuccuga      300

accuggcgau uucugaccuc cuguuucuuu ucacacugcc uuuuuggauc gauuauaaac      360

ucaaggacga uuggguguuc ggggacgcua uguguaaaau ucugagcgga uuuuacuaua      420

ccggccuuua cuccgagauc uucuuuauca uucugcucac gaucgaucgc uaccuggcca      480

uuguccacgc cguguucgcu cugagagccc ggaccguuac auuuggggug aucaccucua      540

uuaucauuug ggcucucgcc auccuggcga gcaugcccgg acuuuauuuc uccaagacac      600

agugggaauu uacccaucac acgugcucuc ugcauuuccc ucacgagagc cuccgcgagu      660

ggaagcuguu ccaggcccuu aaacugaauc ucuuuggccu gguccugccc cuccugguga      720

ugaucauuug uuacacaggc aucauuaaga uccuucugag acggccuaac gagaaaaagu      780

ccaaagcugu gcgccucauu uucgucauca ugaucaucuu uuuccuguuu uggaccccgu      840

auaaucuuac aauucugauu agcguuuucc aagacuuucu cuucacccau gaaugcgaac      900

agucuagaca ccuggaucug gccguccagg ugaccgaggu gaucgcuuac acacacuguu      960

gcgugaaccc cguuauuuau gccuuugugg gggagcgguu ccgcaaguac cucagacagc     1020

uguuucaucg gcgcgucgcg gugcaccuug uuaaguggcu gccuuuccuc uccguggaca     1080

gacuggaacg ggucagcucu acguccccca gcaccggaga gcaugaacug ucugccggcu     1140

uuugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  4348
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt5)

<400>  4348
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agaacccugg ccugccuccu gcuucugggc uguggguacc      120

ucgcucacgu gcuggccgag gaagcggaga ucccccggga agucauugag cgccuugcua      180

gaagccagau ccauuccauu cgggaccugc aacgccuccu ggaaaucgau ucuguuggaa      240

gcgaggacuc ccuggauaca ucucucagag cccacggcgu gcaugccacg aagcacgugc      300

cugagaaacg gccgcugccc auucgcagaa agcggagcau cgaagaggcu gucccugccg      360

ugugcaaaac ccgcacaguu aucuaugaaa uucccagauc ccagguggac ccuaccucug      420

cuaacuuccu uaucuggccc ccuugugucg aggugaagcg gugcacaggg uguugcaaua      480

ccagcuccgu uaaaugucag ccgagccgcg ugcaucacag aucugucaag guggccaagg      540

uggaguacgu ccggaaaaag cccaaacuga aggaaguuca ggugcgccuc gaggaacacc      600

uggagugcgc gugugccaca accucccuua acccugauua uagagaagag gacacgggac      660

ggcccagaga gagcggcaaa aagcgcaagc ggaaaagacu gaagccuacc ugaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  4349
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt5)

<400>  4349
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagaugcu gggcccuguu ccucagccug uguugcuacc      120

uucggcuggu guccgcugag ggcgacccca ucccugagga acucuaugaa augcugucug      180

aucacagcau ucgcuccuuu gacgaucuuc agagacugcu ccauggggac ccgggagagg      240

aagauggcgc cgagcuggac cugaauauga cccggucuca cagcggggga gagcucgaau      300

cccuggcgcg cggcagacgg ucucuuggga gccugacaau cgcugagccc gccaugauug      360

ccgaauguaa gacgcgcacc gaggucuucg agaucuccag acggcucauu gaucgcacaa      420

acgcuaauuu ucugguuugg ccucccugcg uggaagugca aagauguagc ggaugcugua      480

acaaucggaa cguccagugc cgcccuaccc aggugcagcu uagacccguu caagugcgga      540

aaaucgagau cguccgcaag aaaccuauuu ucaagaaagc cacagugacc cuggaagacc      600

aucucgcuug uaagugcgag acaguugccg cggccagacc ggugacccgg ucucccggcg      660

gcucccagga acagagagcu aagacgccuc agacccgcgu cacaauccgg accgugagag      720

ugcgccggcc cccuaaaggg aagcacagaa aauuuaagca uacacacgau aaaaccgccc      780

ugaaggagac gcugggagcu ugaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  4350
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt5)

<400>  4350
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguucg gccuccugcu ucugaccucc gcccucgcug      120

ggcagagaca aggaacacag gccgagucua accugagcuc caaguuucag uucucuagca      180

auaaagaaca gaacggcgug caagaccccc agcacgagcg gaucauuacg gucuccacca      240

augggucuau ccauagcccu cgcuuuccgc acacauaccc cagaaacacc guucuugugu      300

ggcggcuggu ggcggucgaa gagaaugugu ggauucagcu cacauucgau gaacgcuuug      360

gacuggagga cccugaggau gacaucugca aguaugauuu cguugaagug gaggaacccu      420

ccgacggcac cauucugggg agauggugug gaagcggcac agucccuggc aaacagaucu      480

cuaaggggaa ccaaauccgg auucgcuuug uguccgauga guacuucccc agcgagccug      540

gauuuugcau ccauuauaau auuguuaugc cgcaguucac cgaagcugug ucucccuccg      600

uccucccucc cagcgcccug ccucuugacc ugcucaacaa ugccaucacg gcuuuuucua      660

cccuggagga ucuuauuaga uaccuggaac ccgagcggug gcagcucgac cuggaagauc      720

uguaucgccc gacauggcag cuccugggca aagccuucgu guuugggaga aagucccggg      780

uggucgaccu uaaccugcuc accgaggagg uucgccugua cagcuguaca ccuagaaauu      840

ucuccguguc uauccgggag gaacuuaagc gcaccgauac gauuuucugg cccggaugcc      900

ugcucgugaa aagauguggc gggaacugcg cuuguugccu gcacaauugu aacgaaugcc      960

aauguguccc uagcaaggug accaaaaagu aucaugaggu ucugcagcuc cggcccaaaa     1020

caggagugag aggccugcac aagucccuua cagacgucgc ccuggaacac caugaggagu     1080

gcgacugcgu gugucgcggc agcaccgggg gaugaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  4351
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt5)

<400>  4351
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagacuga ucuucgugua cacccucauu ugcgccaacu      120

uuuguagcug ccgggacaca uccgcuacgc cccagucugc cagcaucaag gcgcugcgca      180

augcuaaccu uagacgggau gaccuguauc gcagagauga gaccauucaa gucaaaggca      240

auggguacgu ucaguccccu cgguucccga acucuuaucc ccgcaaucuc cugcuuacau      300

ggagacugca uagccaggaa aacacccgga uccagcucgu guuugacaau caauucggac      360

uggaggaagc cgagaacgau auuugucgcu acgacuuugu ggaagucgag gauaucuccg      420

agacaucuac caucauuaga ggccgguggu gcgggcacaa ggaagugccu ccccgcauca      480

aaagcagaac aaaucagauu aagaucaccu ucaaauccga cgauuauuuu guugccaagc      540

cuggauucaa gauuuacuau agccugcucg aggacuuuca gcccgcugcc gcuucugaaa      600

cgaacuggga guccgugacc agcucuaucu ccggcgucag cuacaauucu ccuuccguga      660

cagauccgac ccugauugcc gacgcgcuug auaaaaagau cgccgaguuc gacacaguug      720

aagaccugcu caaauacuuu aaccccgaga gcuggcagga agaucuggag aauauguauc      780

uugacacccc ucgguaccgc gggagauccu aucaugaucg gaagucuaaa guggaccugg      840

auagacucaa cgacgaugcu aagcgcuaca gcuguacgcc ccggaauuau uccgucaaca      900

ucagagagga acugaagcug gccaacgugg uguucuuucc ucgcugccuc cugguccaac      960

gguguggagg caauugcggc ugugggacag uuaacuggag aagcugcacc uguaauucug     1020

gaaaaacagu gaagaaauac cacgaggugc uucaguucga acccggccau auuaagcgcc     1080

gggggagagc uaaaaccaug gcccuggucg acauccagcu cgaucaccac gagcgcugcg     1140

acugcauuug uuccagccgg ccgccuagau gaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  4352
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt5)

<400>  4352
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugacccaca gcaaguuccc cgccgcuggc auguccagac      120

cucuggacac aucucuccgg cugaaaacgu uuagcuccaa gucugaguac cagcuugucg      180

uuaacgccgu gcgcaaacug caagaaagcg gguucuauug guccgcggug accggaggcg      240

aggcuaaucu ccugcuuucu gccgaaccgg ccgggacauu ucugaucaga gauagcuccg      300

accagcggca uuucuuuacc cucagcguca agacacaguc uggaaccaaa aaccugcgca      360

uucagugcga gggcgggucc uucagccugc aaucugaucc cagauccaca cagccugugc      420

cccgguuuga cuguguucuc aagcuggugc accauuacau gccucccccu ggagcuccga      480

gcuuccccuc uccucccacc gaaccuucca gcgagguccc cgagcagccg uccgcccagc      540

cucuucccgg cucuccuccc cgcagagcuu auuacaucua uagcggcggg gaaaagauuc      600

cccuggugcu cucccggccu cugagcucua auguugccac gcuucaacac cugugccgca      660

aaaccgugaa cggacaucuc gauuccuacg agaaggucac acagcugccg ggccccauca      720

gagaauuucu ggaccaguau gaugcgccuc ucugaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  4353
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt5)

<400>  4353
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugcccagcg ccggccagcu ggcucucuuc gcccugggga      120

ucguccuugc ggcuugccaa gcccuggaga acuccaccuc uccucucagc gccgacccgc      180

ccguugcugc cgcuguggug ucccacuuua augauugucc ugacucucau acacaguucu      240

gcuuucacgg aacguguaga uuccuggucc aggaagauaa gcccgccugc gugugucaua      300

gcggcuacgu uggggcgcgg ugcgagcacg ccgaccuucu ggcugugguc gccgcuuccc      360

agaaaaagca agccauuacc gcgcucgugg uugugucuau cgucgcccug gcugugcuga      420

uuaucacaug ugugcucauu cauugcuguc agguccgcaa acacugcgaa ugguguagag      480

cccugaucug ccggcacgag aagccuagcg cccuucugaa aggacgcacc gcuugcuguc      540

auuccgaaac aguuguguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  4354
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt5)

<400>  4354
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccccuagcg gccugagacu ccugccgcuu cugcuccccc      120

ugcuuuggcu gcucgugcug accccugggc ggcccgccgc uggacugucc acaugcaaga      180

cgaucgacau ggagcucguc aaacgcaaga gaauugaagc cauccggggc cagauucugu      240

cuaaacuucg ccuggcgagc ccucccuccc aaggggaggu uccuccggga ccccucccug      300

aagcugugcu ggcccuuuac aacucuacca gagaucgggu ggccggcgag agcgcugaac      360

ccgagccuga gcccgaagcc gacuauuacg cuaaggaggu cacacgcgug cugaugguug      420

aaacccacaa ugagaucuau gauaaauuca agcaguccac acauucuauu uacauguuuu      480

ucaacaccag cgagcucaga gaagccgugc cggagccugu ccugcugucc cgggcggaac      540

uccgccugcu uagacugaag cucaaagugg agcagcacgu ugaacuguau cagaaguaca      600

gcaauaacuc uuggcgguau cuuuccaauc gccugcucgc ccccagcgac ucuccugagu      660

ggcuguccuu ugaugugaca ggggucguga gacaauggcu gagccgggga ggcgagaucg      720

aaggcuuccg ccucucugcu cauuguuccu gcgacagcag agauaacacc cuucaggugg      780

acaucaaugg guuuacgacc ggacggagag gcgaucuggc cacaauucac gggaugaacc      840

gccccuuccu gcuccugaug gcuacacccc uugagcgggc ccagcaucug caguccucua      900

gacaccgccg ggcgcucgac accaauuacu guuuuagcuc caccgagaaa aacugcugug      960

ucagacaacu guacaucgau uuccgcaagg accugggaug gaaauggauu cacgaaccua     1020

agggcuauca ugccaauuuu ugccucgggc cgugucccua caucuggagc cuggauacgc     1080

aguauucuaa gguucuugcu cuguacaacc agcacaaucc uggagccucc gcugcccccu     1140

gcugugugcc ucaggcccuc gaaccccugc cgauugugua uuacgucggc cggaaaccua     1200

agguggagca acugagcaac augaucguua gaucuugcaa auguagcuga ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  4355
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt5)

<400>  4355
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg ugcugagcgc cuuccucauc cugcaucuug      120

ucaccguugc ucugucccuc ucuacaugua gcacgcugga cauggaucag uuuaugagaa      180

agcggauuga ggccauccgc ggccaaauuc uuuccaaacu gaagcucacc ucucccccug      240

aagacuaucc ggagcccgaa gaggugccuc ccgaagugau cagcauuuac aacuccacaa      300

gagaucugcu gcaggagaaa gcgucucggc gcgcugccgc cugcgagaga gaacggagcg      360

acgaggaaua uuacgcuaag gaggucuaua aaaucgauau gccucccuuc uuuccuuccg      420

agaaugccau cccgcccacc uucuaccgcc cuuauuuuag aauugugcgg uucgacguua      480

gcgcuaugga aaagaacgcc ucuaaucucg ugaaggcgga guuucgcguc uucagacugc      540

agaaccccaa agcccgggug ccugaacagc gcaucgagcu uuaccaaauu cugaagucca      600

aagaucucac aagccccacc cagagauaca ucgacucuaa gguugugaaa acacgggcug      660

aaggggagug gcuguccuuu gaugucaccg acgccgugca cgaguggcuu caucacaagg      720

aucgcaaucu gggauucaag auuagccucc auuguccgug cuguacguuu gugccuucua      780

acaauuauau cauucccaac aaauccgagg aacuggaagc uagauucgcc ggcaucgacg      840

ggaccagcac auacaccucc ggagaucaga agacaaucaa aucuacccgg aagaaaaaua      900

gcggcaagac gccucaucug cuccugaugc uucugcccuc cuauagacuc gagagccagc      960

aaacaaaccg ccggaaaaag agagcgcugg acgccgcuua cugcuuucgc aauguccagg     1020

acaacuguug ccuucggccc cuguauauug auuucaagag agaccucggg uggaaaugga     1080

uccacgaacc uaagggauac aaugccaacu ucugugcugg cgccugcccg uaucuguggu     1140

cuuccgauac ccagcacagc cgcguucugu cucucuacaa uacaauuaac cccgaggcca     1200

gcgcuucccc uuguugcgug ucucaggacc uggagccccu uaccauccug uacuauauug     1260

gcaaaacccc uaagaucgaa caacucagca acaugaucgu gaaauccugc aaguguagcu     1320

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  4356
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt5)

<400>  4356
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacc uucagagagc ccucgugguc cuggcucugc      120

ugaacuucgc caccguuagc cucucccugu cuacaugcac gacccuugac uuuggccaua      180

ucaaaaagaa acggguggag gcgauucgcg ggcaaauccu gagcaagcuc agacugacau      240

cucccccuga accgaccgug augacacacg uccccuacca ggugcuggcu cucuauaauu      300

ccacccggga gcugcuugaa gagaugcaug gagaacgcga ggagggcugu acacaggaaa      360

acaccgagag cgaauacuau gccaaagaga uucacaaguu cgauaugauc caggggcugg      420

ccgagcauaa ugaacucgcu guuugcccua agggaauuac guccaaagug uuuagauuca      480

acgucucuag cguggagaag aaucggacca accuguuucg cgccgaguuc agaguucuuc      540

gggugcccaa uccuuccagc aaacgcaacg aacaaagaau cgaacuguuu cagauccucc      600

ggcccgacga gcacauugcu aagcagcgcu acaucggcgg gaaaaaucug ccuacaagag      660

gaaccgccga guggcugucu uucgauguca cagacaccgu gcgggaaugg cuccugcgca      720

gagaguccaa ccuuggccug gaaauuagca uccacugucc gugccauacg uuucagccca      780

auggcgauau ucucgagaac auccacgaag ugauggagau uaaguucaag ggggucgaca      840

augaggauga ccauggacgg ggcgaucugg ggagacuuaa aaagcaaaaa gaccaccaca      900

acccucaucu gauccucaug augauucccc cucaccgccu ggauaauccc ggacagggcg      960

ggcagcggaa gaaaagagcg cuggacacaa acuauuguuu ucgcaaccuc gaagagaauu     1020

gcuguguucg gccgcuguac aucgauuuca gacaggaccu uggauggaag ugggugcaug     1080

aaccuaaagg cuauuacgcc aacuuuugcu cuggccccug uccuuaccug cgcuccgcug     1140

acaccacaca cagcaccgug cucgggcugu auaauacccu uaaccccgag gccucugcuu     1200

cccccugcug ugucccucaa gaucuggaac cgcucacaau ccuguacuau gugggacgga     1260

cgcccaaggu ugagcagcug agcaauaugg uggucaaguc cugcaaaugc ucuugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4357
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt5)

<400>  4357
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccccgugg cugucugggc cgcgcuggcu guuggccucg      120

agcugugggc cgccgcucac gcccuuccug cucagguggc cuucaccccg uacgcgcccg      180

aaccugggag cacaugcaga cugcgggagu auuacgacca aacggcccag auguguugcu      240

ccaaguguuc ucccggacag caugcuaaag uguuuugcac caagacaagc gauaccgucu      300

gugacuccug cgaagauucu acauauaccc agcucuggaa cugggugccu gagugucuga      360

gcugcggcuc ccgcuguucu agcgaccaag uugaaacaca ggccugcacc agagagcaga      420

aucggaucug uacgugccgc cccggguggu acugcgcucu uuccaaacag gagggaugua      480

gacugugcgc cccucuccgg aagugucgcc cgggcuucgg gguggcgaga cccggaaccg      540

aaacaagcga ugucgugugc aaaccuugug cccccggcac cuuuucuaac acaaccucca      600

gcacggacau uugccggccu caccaaaucu guaauguugu ggcuauuccc ggcaacgccu      660

cuauggaugc ugucugcaca uccaccagcc cgacacgcuc uauggccccu ggggccgugc      720

aucugcccca gccugugucc accagaagcc agcacaccca gcccacaccc gagccuucca      780

cggcuccguc uaccagcuuc cugcucccca ugggaccuuc cccucccgcg gaaggcagca      840

caggggacuu ugcccugccc gucggacuua ucguuggcgu gaccgcucug gggcuccuga      900

uuaucggagu ggucaauugu gugaucauga cacaaguuaa gaagaaaccg cuuugccugc      960

agcgggaggc caaggugccu caucuccccg ccgauaaagc ucgcggcacc cagggcccug     1020

agcaacagca ucugcugauu acggcccccu cuuccagcuc uagcucccuc gaaucuagcg     1080

cguccgcucu ggacagacgg gccccuacac gcaaccagcc ccaggccccg ggggucgagg     1140

cuagcggagc cggcgaagcu agagccucua ccggguccag cgauucuucc ccuggaggcc     1200

acgggaccca agugaauguu acauguaucg ugaacgucug cagcuccucu gaccacagcu     1260

cccagugcuc uagccaggcg uccagcacca ugggagauac agacucuucc cccagcgagu     1320

cucccaagga cgaacaggug ccuuucucca aagaggagug ugccuuucgg agccaacuug     1380

aaacgccgga gacccugcuc ggcucuacag aagagaagcc ccugccucuu ggcguccccg     1440

augcugggau gaagccuagc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  4358
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt5)

<400>  4358
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgugauga gacuguuccc uugcuuucuc cagcugcuug      120

ccggccuggc ucucccggcc guucccccuc aacagugggc gcugagcgcu gggaacggau      180

ccucugaggu cgaaguggug cccuuccagg aggucugggg ccggagcuac ugucgcgccc      240

uugaaagacu gguggacguu guguccgagu auccuucuga agucgagcac auguuuagcc      300

ccuccugcgu gucucuccug cgguguaccg ggugcugugg agaugagaau cugcauugcg      360

uuccugugga aacagccaac gucacgaugc agcuccugaa gauccgcagc ggcgacagac      420

cguccuacgu ggagcuuacc uucagccaac acgugcggug ugaaugccgc ccccugagag      480

agaaaaugaa gccugagcgg cgcagaccca aagggcgggg aaagcgcaga cgggaaaaac      540

agcgcccuac agauugucau cucugcggcg acgcuguccc cagacgguga ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  4359
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt5)

<400>  4359
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgacagac agacagauac ggcccccagc ccuuccuacc      120

accuucuccc gggccggcgc agaaccgugg acgcugccgc gucucggggg caaggacccg      180

agccugcucc cggcggggga gucgaaggcg uuggggcccg cggaguggcc cugaagcugu      240

ucgugcagcu gcucggcugc agcagauuug gcggggcugu cgugcgggcc ggagaggcug      300

aaccuuccgg cgccgcgcgc ucugccagcu ccgggagaga ggaaccccag ccugaggagg      360

gagaagagga agaggagaaa gaagaggaac ggggcccgca guggcgccug ggggcuagaa      420

agcccggauc uuggacaggc gaggccgcug uuugugccga uagcgcgccu gccgcucggg      480

cuccccaagc ccuugcccgc gccuccggca gagggggacg gguggcucgc agaggcgcgg      540

aagagagcgg gccuccccau ucuccguccc ggagaggaag cgccucucgc gcuggcccug      600

ggcgggccuc cgagaccaug aacuuccugc ucagcugggu ccacuggucu cuggcccugc      660

uccuguaucu ucaucacgcu aaaugguccc aggccgcgcc cauggcugaa ggaggcggcc      720

agaaucauca cgaggugguu aaguuuaugg acguguacca gagaagcuau ugccacccua      780

ucgaaacacu ggucgauauu uuccaagagu accccgacga aaucgaguau auuuuuaaac      840

ccuccugugu gccucucaug cgcugcgggg gauguugcaa cgaugagggc cuggaaugug      900

ugccgaccga ggaaucuaau aucacaaugc agauuaugcg gaucaagccc caucaggggc      960

agcacaucgg agagaugagc uuccuucaac auaacaagug cgaauguaga ccuaaaaagg     1020

accgcgcccg gcaggagaaa aaguccguca gaggcaaagg gaagggccag aagcgcaaac     1080

ggaagaaaag cagauacaag ucuugguccg uuuauguggg agcccgcugc ugucugaugc     1140

ccuggagccu cccuggcccc cacccgugcg ggccuugcuc ugagcggaga aaacaccugu     1200

uugugcaaga uccccagacc uguaagugca gcuguaaaaa uacggacucc cggugcaagg     1260

cucgccagcu ggaacucaac gagagaaccu gucggugcga uaagccuaga cgcugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4360
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt5)

<400>  4360
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggucc cuggcccuuc      120

ugcucuaccu gcaucacgcu aaguggucuc aggccgcgcc cauggcugag ggcgggggac      180

aaaaucauca cgaagucguu aaauuuaugg acguguauca gagaagcuac ugccauccua      240

ucgagacccu uguggauauu uuccaggaau auccggacga gaucgaauac auuuuuaagc      300

ccuccugugu cccucugaug cggugcggcg gguguugcaa cgaugaggga cucgagugug      360

ugcccacaga agagucuaau aucacgaugc agauuaugcg caucaaaccu caccaaggcc      420

agcacaucgg ggaaaugagc uuccugcagc auaacaagug cgaguguaga cccaaaaagg      480

accgggcccg ccaggagaag aaauccguua gaggaaaggg caaaggccaa aagcggaaac      540

gcaagaaguc uagauauaaa agcugguccg uguacgucgg ggcccggugc ugucugaugc      600

cuuggagccu cccgggaccc cacccuugcg gccccuguuc ugaacgcaga aagcaucugu      660

uugugcagga uccucagacc ugcaaaugcu ccuguaagaa uacagacagc cggugcaaag      720

cucgccagcu ugagcugaac gaaagaaccu gucggugcga uaagccccgc agaugaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  4361
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt5)

<400>  4361
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcccccugc ucagacggcu gcuucuggcc gcucuccugc      120

agcuugcccc ugcgcaagcu ccgguguccc agcccgacgc cccuggccac cagcgcaagg      180

ucguuucuug gaucgaugug uacaccagag ccacaugcca gccccgggag guggucgugc      240

cucugacggu ugaacucaug gggaccgugg cuaagcaacu gguccccagc ugugugacag      300

uucagcgcug cggaggcugu ugcccugacg augggcugga gugugugccg accggacagc      360

aucaggucag aaugcaaauu cucaugaucc gguaucccuc cucucagcug ggcgaaauga      420

gccuugagga acacucccag ugcgaguguc gcccuaagaa aaaggacucu gccgugaaac      480

ccgauagagc ugccacaccu caucaccggc cccagccgcg cagcgugccu gggugggacu      540

ccgcgcccgg agccccuagc cccgcugaua uuacccaucc caccccugcc ccgggccccu      600

cugcucacgc cgcgccuucc acaacgagcg cccugacccc cggcccugcu gccgcugccg      660

ccgacgcugc ggccucuucc gucgcuaaag ggggagccug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  4362
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt5)

<400>  4362
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caucugcucg gcuucuuuag cguggccugc ucccugcuug      120

cugccgcgcu gcuccccggg ccuagagagg cuccggccgc cgcugccgcu uucgaaucug      180

gacuggaccu uagcgaugcc gagcccgacg cgggcgaagc caccgcuuac gccuccaagg      240

aucuggagga acagcuccgg ucugucagcu ccguugacga gcugaugaca gugcuguauc      300

cugaguacug gaaaauguau aagugucaac uccgcaaagg gggauggcag cacaacagag      360

aacaggcuaa ucugaacucu cggacggagg aaaccaucaa guuugccgcg gcccacuaca      420

auacagagau ucuuaaaagc aucgauaacg aguggcgcaa gacccagugc augcccagag      480

aaguguguau ugacgucggc aaggaguucg ggguggcuac aaauaccuuu uucaaaccuc      540

ccugcguuuc cguguaucgg uguggaggcu gcuguaacag cgaaggccug caaugcauga      600

auacaucuac cuccuaccuc agcaagacgc uguuugagau caccgucccu cuuucucagg      660

ggccgaaacc cgugacaauu uccuucgcca accauaccag cugucgcugc augucuaagc      720

uggauguuua uagacaggug cacuccauca uccggcgcag ccucccugcu acacugcccc      780

agugucaagc cgccaauaaa accugcccua cgaacuacau guggaauaac cauauuugca      840

gaugucuggc ucaggaagac uuuauguucu ccucugaugc gggagacgau agcacagacg      900

gcuuucacga uaucugcggg cccaauaagg agcucgacga ggaaaccugu cagugcgucu      960

gucgggccgg acugcgcccg gcuuccugcg gcccucacaa ggagcuugac agaaacagcu     1020

gucagugcgu guguaaaaau aagcuguucc ccucucaaug cggggccaac cgggaauuug     1080

augagaacac augucagugc gugugcaaac gcaccugucc uagaaaucag ccccucaacc     1140

ccggaaagug cgccugugaa ugcaccgagu ccccucaaaa augucugcuu aagggcaaaa     1200

aguuccauca ccagacaugc agcuguuacc ggagaccgug cacgaaucgc cagaaggcuu     1260

gugagcccgg cuucucuuau agcgaagagg ucugccggug uguuccuucc uacuggaaaa     1320

gaccccagau gucuugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  4363
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt5)

<400>  4363
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagagu ggguggucgu uaacguguuc augaugcugu      120

augugcagcu cguccaaggc agcuccaaug aacacgggcc cgugaagcgg ucuagccagu      180

ccacccugga gcgcucugaa cagcagauca gagccgcuag cucccuugag gaacugcucc      240

ggauuacaca uucugaggac uggaaacugu ggcgcugcag acuucggcuc aagagcuuua      300

cguccaugga uagccgcucu gccucccaca gaagcacccg guucgcggcu acauuuuacg      360

acaucgagac ccugaaaguu auugaugaag aguggcaacg cacacagugu ucuccuagag      420

aaaccugcgu ggaggucgcc uccgagcugg gaaagagcac aaacaccuuc uuuaaaccgc      480

ccugugugaa uguuuuccgg ugcggcgggu guugcaacga agagucucug aucuguauga      540

auacguccac cagcuauauu uccaagcagc ucuuugaaau cucugugccu cugacaagcg      600

uccccgagcu ugugccugug aaggucgcca accauaccgg augcaaaugu cugcccacag      660

cuccucgcca cccguacucc aucauuagac ggagcaucca gauucccgaa gaggaccgcu      720

gcucucauuc caagaaacuc uguccuaucg auaugcugug ggacagcaau aagugcaaau      780

gcguucuuca agaggaaaac ccccuggccg gcaccgagga ucacucucac cuccaggaac      840

cugcucugug ugggccccau augauguucg acgaggauag augcgaaugu gugugcaaga      900

cgccgugucc uaaggaccug auucagcacc ccaaaaauug cagcuguuuu gagugcaagg      960

agucccucga aacauguugc cagaaacaua agcuguucca cccugauacc uguucuugcg     1020

aggaccggug ccccuuucac acaagacccu gugccagcgg aaaaaccgcg ugcgccaagc     1080

auugucgcuu cccuaaagaa aagcgggcug cccaaggccc gcacuccaga aagaaccccu     1140

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  4364
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt6)

<400>  4364
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucagacg aaacaggauu ugaacacuca ggauuauggg      120

uaucaguauu agcaggauua cuacucggag caugccaagc acacccaauc ccagacucau      180

caccauuauu acaauucgga ggacaaguca gacaacgaua cuuauacaca gacgacgcac      240

aacaaacaga agcacauuua gaaauaagag aagacggaac aguaggcgga gcagcagauc      300

aaucaccaga aucacuacua caacuaaaag cacuaaaacc aggaguaaua caaauauuag      360

gaguaaaaac aucaagauuc uuaugccaaa gaccagacgg agcacuauac ggaucauuac      420

acuuugaucc agaagcaugc ucuuucagag aacuacuacu agaagacgga uacaacguau      480

accaaucaga agcucaugga cuaccuuuac accuaccagg aaacaaauca ccacacagag      540

auccagcucc cagaggaccc gcaagauucc uaccauuacc aggauuacca ccagcauuac      600

cagaaccacc aggaauacua gcaccacaac caccagacgu aggaucauca gacccauuau      660

caaugguagg accaucacaa ggaagaucac caucauacgc aucauaagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  4365
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt6)

<400>  4365
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacucauuuc caccacuauu auuacuacua uuuuggggag      120

ucguaucaca uagcuuuccc gcaacacuag aaacccaaga acaagacgua gacuuaguac      180

aaaaauaucu agaaaaauac uauaaccuca aaaacgacgg aagacaaguc gaaaaaagaa      240

gaaacagcgg accaguugua gaaaaacuaa aacaaaugca agaauuuuuc ggauuaaaag      300

uuacuggaaa accagacgca gaaacacuaa aaguaaugaa acaaccaaga ugcggaguac      360

cagauguagc acaguucgua uuaacagaag gaaacccacg uugggaacaa acacaucuua      420

cauacagaau ugaaaauuac acaccugacc uaccaagagc agacguagac cacgcaauag      480

aaaaagccuu ucaauuaugg ucaaacguaa caccauuaac auucacaaaa guuucugaag      540

ggcaagcaga cauaaugauc ucauuuguua gaggagacca ccgagacaau agcccauucg      600

acgggccagg aggaaaccua gcacaugcuu uccaaccagg accuggaaua ggaggcgacg      660

cacauuucga cgaagacgaa cgauggacaa acaauuucag agaauacaac cuacauagag      720

uagcagccca cgaauuaggc cacagccuag gcuuaucaca cucaacagac auuggagcuc      780

uaauguaccc uuccuacaca uuuucaggag acguacaauu agcccaagac gauauagacg      840

gaauacaagc aauauacgga cgaucacaaa acccaguaca accaauagga ccacaaacac      900

caaaagcaug cgacucaaaa uuaacauuug acgccauaac aacaauaaga ggagaaguaa      960

uguuuuucaa agaccgauuu uauaugagaa caaauccauu cuacccagaa guagaauuaa     1020

acuuuauaag uguauucugg ccucaauuac caaacggauu agaagcagca uaugaauuug     1080

cagacagaga cgaaguacga uucuuuaaag gaaauaaaua cugggccgua caaggacaaa     1140

acguauuaca uggauaccca aaagacauau acagcucauu cggguuucca agaacaguaa     1200

aacacauaga cgccgcauua ucagaagaaa acacaggcaa aacauauuuu uucguagcaa     1260

acaaauacug gagauacgac gaauacaaaa gaucaaugga cccaggauau ccaaaaauga     1320

uagcacacga uuucccuggc auugggcaca aaguagaugc aguauucaug aaagauggcu     1380

uuuucuacuu cuuucacgga acucgacaau acaaauucga cccaaaaaca aaaagaauac     1440

ucacacuaca aaaagcaaac aguugguuca auuguagaaa aaacuaagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  4366
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt6)

<400>  4366
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauucauucc caccacuacu auuauuauua uucuggggag      120

uaguaucaca uucauuugua cuaacugaag gaaauccuag augggaacaa acucacuuaa      180

ccuauagaau agaaaacuau acaccagacc uaccaagagc cgacgucgac cacgcaauug      240

aaaaagcauu ccaauuaugg aguaacguaa caccacuaac auucacaaaa guaucagaag      300

gacaagcaga cauaaugaua ucauuuguca gaggagacca ccgagacaac ucaccauuug      360

acggaccugg aggaaaucuc gcacacgcau uccaaccagg accaggaaua ggaggagacg      420

cacauuuuga ugaagaugaa cgauggacca acaauuuuag agaauacaac cuacaccgag      480

uagccgcaca cgaacucgga cacagccuag gacuaucaca cucaaccgac aucggagcac      540

uaauguaccc aucauacaca uucuccggag acguccaacu agcucaagac gacauagacg      600

gaauacaagc aauauacgga agaucacaaa auccuguaca accaauagga ccacaaaccc      660

caaaagcaug cgacucaaaa uuaacauuug acgcaauaac cacaauuaga ggugaaguaa      720

uguuuuucaa agauagauuu uacaugagaa caaaucccuu cuauccagaa guagaauuaa      780

auuucauauc aguauucugg ccacaacuac caaauggauu agaagcagca uacgaauuug      840

cagauagaga cgaaguaaga uucuucaaag gcaacaaaua cugggcagua caaggccaaa      900

acguacuaca cggauauccu aaagacauau acucuuccuu uggauuuccu agaacaguaa      960

aacacauaga ugccgcacua ucagaagaaa acaccggaaa aacauacuuc uucgucgcca     1020

auaaauacug gagauacgac gaauauaaac gaucaaugga cccagguuac ccaaaaauga     1080

uagcacacga uuucccagga auaggacaca aaguugacgc agucuuuaug aaagacggau     1140

uuuucuacuu cuuucacgga acacgacaau acaaauucga ucccaaaacu aaaagaaucc     1200

uaacuuuaca aaaagccaau ucuugguuua auuguagaaa aaacuaagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  4367
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt6)

<400>  4367
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaaaaaca uacucaaaau ucuaauggac ucauacucga      120

aagaaucaaa aauacaaaca guccgcagag uuacaucagu cucguuacua gcaguauacc      180

ugacgaugaa cacauccucg uuaguacucg cuaaaccuau agaaaauacc aacgauacca      240

guauaaaaaa cguagaaaaa uuaagaaaug caccaaacga agaaaacagu aaaaaaguag      300

aagacaguaa aaaugacaaa guagaacaug uaaaaaacau agaagaagca aaaguugaac      360

aaguagcacc agagguaaaa uccaaaagca cauuaagaag cgcgucaauc gccaacacaa      420

auucagagaa guacgacuuc gaauacuuaa acggauuaag uuauacagaa cuaacaaauc      480

ucauuaaaaa uaucaaaugg aaccagauaa auggacuauu uaauuacuca acaggaucac      540

aaaaauuuuu cggagacaaa aauagaguac aagcaauuau aaacgcuuua caagaaagcg      600

gacgaacgua uacagcaaac gauaugaaag gaauugaaac auucacagaa guacuacgcg      660

cugguuuuua ucugggcuau uauaacgacg gacuaucaua ccucaacgac cgaaacuucc      720

aagauaaaug cauaccagcg augauugcaa uucaaaaaaa cccaaacuuu aaacuaggaa      780

ccgcagucca agaugaagua auaacgucgc ucggaaaacu aauaggaaau gcaagcgcua      840

augcagaagu uguaaauaac uguguucccg uacuaaaaca auuccgagaa aauuuaaauc      900

aauacgcacc agauuacguc aaaggaacgg ccguuaauga acuuaucaaa ggaauagaau      960

uugauuucuc aggagcagcu uaugaaaaag acguaaagac uaugccaugg uacggaaaaa     1020

uagaucccuu uauaaaugag cugaaggcac uaggccuuua cggaaacauc acaucagcua     1080

cagaaugggc gucagauguc gggauauacu aucuaucaaa auucggacuu uacucaacca     1140

accgaaauga uauaguacaa uccuuagaaa aagcaguaga uauguauaaa uacggaaaaa     1200

uagcuuucgu cgcaauggaa cgaaucacau gggauuauga cgguauagga agcaauggaa     1260

aaaaaguaga ucaugacaaa uuccuagaug acgcagaaaa acauuaccuc cccaaaacau     1320

acaccuucga uaacggcaca uucauaauaa gagcuggaga caaaguauca gaagaaaaaa     1380

ucaaacguuu auacugggca ucacgagagg uuaaaucaca auuccauaga guagucggua     1440

augacaaagc auuagaagua ggcaaugcag acgacguacu cacaaugaaa auauucaauu     1500

cuccugaaga auauaaauuu aauaccaaca uuaacggagu aucuacagac aauggaggcc     1560

uuuacauaga accaagagga acguucuaua ccuacgaaag aacaccacaa caaucaaucu     1620

uuucauuaga agaacuauuu agacacgaau acacacacua ucugcaagca cgauaccugg     1680

uggauggacu auggggacaa gggccauuuu augaaaaaaa ccgcuuaaca ugguuugaug     1740

aaggcacagc cgaauuuuuc gcaggaucaa ccagaacauc gggugucuua ccacggaaau     1800

caauacucgg guacuuagca aaagacaaag uagaucauag auauucauua aaaaaaacac     1860

uaaauagugg auaugaugac ucggauugga uguuuuacaa cuaugguuuu gcgguagcac     1920

auuauuuaua ugaaaaagau augcccacau ucauaaaaau gaacaaagcu auauuaaaua     1980

ccgauguaaa gagcuaugau gaaauaauaa aaaaacucag ugaugaugca aauaaaaaca     2040

cugaauauca aaaccacaua caagaacuag cagacaaaua ccaaggagca gguauuccgu     2100

uaguuucaga ugauuacuua aaagaccacg gauauaaaaa agcaucagaa guauacagug     2160

aaauaucgaa agcagccagc cuuacaaaca ccucaguaac agcagagaaa agucaauauu     2220

ucaacacauu uacacuaaga ggaacauaca cgggggaaac cucaaaagga gaauuuaaag     2280

auugggauga aauguccaaa aaacuagacg gaacacuaga gagcuuagcu aaaaacaguu     2340

ggagcggaua caaaacuuua acggcauacu uuacuaacua ccgaguuaca agugacaaua     2400

agguucaaua cgacguagua uuucacggag uacuaacaga caacgcugau auuaguaaca     2460

acaaagcgcc uaucgcuaaa guaacaggac caucgacugg ggcagucgga aggaacauag     2520

aauuuucugg gaaagacagu aaagaugaag acggaaaaau aguuaguuac gauugggauu     2580

uuggcgaugg agcuaccucu cguggaaaga acucugugca ugcauacaaa aaagcaggaa     2640

cauauaacgu aacccuaaaa guaacagacg acaaaggagc aacagcuaca gagagcuuua     2700

ccauagaaau aaaaaacgaa gauacaacga caccaauaac aaaagagaug gaaccuaaug     2760

augacauaaa agaagcuaac ggacccauag uggaaggagu aacagugaaa ggagaccuga     2820

auggcagcga ugacgcugau acuuuuuauu ucgaugucaa agaagacggu gacguaacca     2880

uugaacuacc guacagcggc aguucaaauu uuacaugguu gguauauaaa gaaggagacg     2940

accaaaacca cauagcaucu ggaauagaua aaaauaacuc aaaaguuggu acauuuaaaa     3000

guacaaaagg uagacacuau guauucaucu auaaacacga cagcgcauca aacauauccu     3060

auucccucaa uauaaaggga cuaggaaaug aaaaacugaa agaaaaagaa aauaacgauu     3120

ccagugacaa agcaacugua aucccaaauu uuaauacaac aaugcaagga ucuuuauuag     3180

gagacgauag ucgcgacuau uacucauuug aagugaaaga agaaggagaa guaaauauag     3240

aacuugacaa aaaagacgag uucggaguaa ccuggacucu ccacccagaa ucaaauauaa     3300

acgauagaau cacauacgga caaguagacg guaacaaagu cucaaauaag guaaaacuua     3360

gaccagggaa auacuauuua cucguauaua aauacucugg cagcggcaac uacgaguuac     3420

ggguuaacaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  4368
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt6)

<400>  4368
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguca ccuuuauaag ucuacuuuuc uuauuuuccu      120

cagcauauag cauagcaaau acaaauuccg aaaaauauga cuucgaauac cuaaacgguc      180

uuaguuacac agaauuaacu aaccuaauua aaaacauaaa auggaaucaa auaaauggcu      240

uauuuaauua uucaacaggu agucaaaaau ucuucggaga uaaaaacaga gugcaagcaa      300

uaauaaacgc ccuacaagag ucaggacgaa cauauacagc aaaugacaug aaaggaauag      360

agacauucac agagguauua cgugccggau ucuaccuagg auacuacaac gacgguuuau      420

cuuacuuaaa ugacagaaac uuccaggaua aauguauacc agcaaugaua gcaauacaga      480

aaaacccuaa uuucaaacuc ggaacggcgg uucaagacga aguaauuaca ucuuuaggua      540

aauugauagg aaacgcauca gcgaacgccg agguaguaaa caauugcgua ccgguccuua      600

aacaauuuag agaaaaucua aaccaauaug caccagacua cgugaaagga acagcaguga      660

augaauuaau aaaaggcauu gaguucgacu ucucaggagc agcauaugaa aaagauguaa      720

aaacaaugcc augguacgga aaaauagauc cauucauaaa ugaacuaaaa gcauuaggau      780

uauacggcaa caucaccagu gcaacugaau gggcaucaga ugucgggaua uacuauuuau      840

caaaauucgg acucuauagc acaaaccgaa acgacauagu acaaucacua gagaaagcag      900

uagacaugua caaauacggg aaaauagcau uuguagccau ggaacgaauu acaugggacu      960

acgauggcau agguagcaau ggaaagaaag uagaucacga uaaauuccuu gacgacgcag     1020

aaaaacacua ucuuccuaaa acauacacuu uugauaacgg uaccuucaua auacgagccg     1080

gugauaaagu aagcgaagag aaaauaaaaa ggcuauauug ggcaagcaga gaagucaaaa     1140

gccaauuuca uagaguagua ggaaaugaca aagcacuaga aguuggaaac gcugacgaug     1200

uucuaacaau gaaaaucuuc aacucaccug aagaauacaa auucaacaca aacauaaaug     1260

gaguaaguac cgacaacgga ggauuauaua uagaacccag ggggacguuu uauaccuacg     1320

agagaacccc ucaacaaucu auauuuuccu uagaagaauu auuucgacau gaauacacac     1380

acuauuuaca agcacgauau uugguagaug gacuaugggg acaaggacca uuuuaugaga     1440

aaaacagacu uacgugguuc gacgaaggaa cggcagaguu cuuugcagga aguacaagaa     1500

caaguggagu auuaccaaga aaaucaauac uagguuacuu agcaaaagac aaaguagauc     1560

acagauacag ccuaaagaaa acacugaaua gcgguuauga ugacagugau uggauguucu     1620

auaauuacgg auucgcagua gcucacuauc uauaugaaaa agauaugcca acauucauca     1680

aaaugaauaa agcaauacuu aacaccgacg uuaaaucaua ugacgaaaua auaaagaaau     1740

uaagugacga cgcaaacaaa aauaccgaau accaaaacca cauccaagaa cuagcagaca     1800

aauaucaagg ugcaggaaua ccauuaguau cagacgacua ccucaaagac cauggauaca     1860

agaaagcguc cgaaguauac ucagaaauaa guaaagcagc aucauugacu aauacuucag     1920

uaacagcaga aaaaucacaa uacuuuaaca cauucacacu ucgcggaaca uauacgggag     1980

aaaccucaaa aggugaauuu aaagauuggg acgaaaugag uaaaaagcuc gacggcacuc     2040

uagaaucauu ggcuaaaaac uccuggucag gauauaaaac acuaacagcc uacuucacca     2100

auuacagagu caccucagau aauaaaguac aauaugacgu aguauuucau ggagucuuaa     2160

cagacaacgc ugauauaagu aacaauaaag cgccuauagc gaaaguaaca ggaccaucaa     2220

cgggagcagu aggaagaaau auugaguucu caggaaagga uagcaaagac gaagacggaa     2280

aaauuguauc uuaugauugg gauuucggag auggagcaac cucaagaggg aaaaacagug     2340

ugcaugccua caagaaagca ggaacuuaua auguaacacu aaaagugaca gaugacaaag     2400

gagcgacagc aacagagagc uucacgauug aaauuaaaaa cgaagauacu acaacaccca     2460

uaacaaaaga aauggaacca aaugaugaca uaaaagaagc aaacggaccg auaguggaag     2520

gcguaacggu aaaaggagac uuaaauggaa gugaugacgc cgacacauuu uacuuugaug     2580

uuaaagaaga cggugauguc acaauagaau uacccuacuc ugguaguucc aacuucacuu     2640

gguuaguaua caaagaagga gaugaucaaa aucauauagc auccggaaua gacaaaaaca     2700

auagcaaagu aggcacauuu aaauccacaa aaggacguca uuauguuuuc auuuacaaac     2760

acgauagugc aaguaacaua aguuauucuc uaaauauaaa aggacuaggu aaugaaaaac     2820

uaaaagaaaa agaaaacaac gauagcagug acaaagcuac uguuauccca aacuucaaca     2880

ccacaaugca aggcagcuua cucggagacg auucacgaga uuauuacagc uucgaaguaa     2940

aagaagaggg ggaaguaaac auagaacuag auaagaaaga cgaauuugga guaacaugga     3000

cacuacaccc ggaaucgaac auaaaugaca gaaucacaua uggacaagua gacggaaaca     3060

aaguaucaaa uaaagucaaa cuaagaccug gcaaauauua ccuauuagug uauaaauauu     3120

caggaucagg uaauuacgaa cugagaguca auaaauaagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  4369
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt6)

<400>  4369
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa cuuucauaag ucuucuuuuc cuuuucucuu      120

cagcauacuc gaugaagaaa aacauacuaa aaauacucau ggauuccuau agcaaagaaa      180

guaaaauaca aacaguacgg agaguuacau caguaagucu auuagcagua uaccuaacaa      240

ugaauacaag cuccuuagua uuagcaaagc caaucgaaaa cacaaacgau acgucaauua      300

aaaacguaga aaaauuacga aacgcaccua augaagaaaa cucaaagaaa gucgaagaca      360

gcaaaaacga uaaagucgag cacgugaaaa auauagaaga agcaaaagua gaacaaguag      420

ccccagaagu aaaaaguaaa ucaacucuaa gaucugcuuc acgcagacga cguaaacgaa      480

uagccaacac aaauucagaa aaauaugauu ucgaauaccu aaacggguua ucauacacag      540

agcuaacgaa ucuaaucaaa aacauaaaau ggaaccaaau aaauggccua uuuaauuaua      600

gcacaggauc ccaaaaauuc uucggcgaca aaaaucgagu acaagcaaua auuaaugcac      660

uacaggaauc uggcagaaca uauacugcua augacaugaa aggaauagaa acauuuacag      720

aaguacucag agcaggauuu uauuuagguu auuauaauga cggcuuaagu uaccuaaaug      780

auagaaacuu ucaagauaaa ugcauaccug caaugaucgc aauacagaaa aacccaaacu      840

uuaaacuagg gacagcggua caagacgaag uaauaaccag cuuaggaaaa cucaucggaa      900

acgcuucugc aaacgcggaa guuguaaaca acugcguacc aguacuaaaa caauuccgag      960

aaaaccuaaa ucaauacgcu ccagauuaug uaaaaggaac ggcuguaaac gaauuaauaa     1020

aagguaucga auuugauuuc agcggcgcag ccuaugaaaa ggacgucaaa acgaugccau     1080

gguauggaaa aauagaccca uucauaaaug aacugaaagc acucggacuu uacgguaaua     1140

uaacaagugc uacagaaugg gcaucagacg uaggaauaua uuauuuauca aaauucggau     1200

uauacucaac aaauagaaau gacauaguac aaagucuaga aaaagcgguc gacauguaca     1260

aauauggcaa aauagcauuu guagcuaugg aacgcauaac augggacuau gauggaauag     1320

guucuaacgg uaagaaaguu gaucaugaua aauucuuaga ugacgcagaa aaacacuacu     1380

uaccaaaaac auauacauuc gacaacggca ccuuuauaau acgugccgga gacaaaguua     1440

gugaagagaa aauuaaacga cuauacuggg cuucgagaga aguaaaaucu caauuucaca     1500

gagucguggg aaacgauaaa gcacuagaag uuggaaacgc agaugauguc cucacaauga     1560

aaaucuuuaa uuccccggaa gaauacaaau uuaauacgaa uaucaacggc gugucaacug     1620

auaauggagg acuguauaua gaaccacgag gaacauucua cacuuaugaa agaaccccgc     1680

aacaaagcau uuucucccua gaagaacuau ucaggcauga auauacacau uaccuccaag     1740

ccagauaccu aguugaugga cuauggggac aaggaccguu uuacgagaaa aaucgauuaa     1800

ccugguuuga ugaaggaacg gcagaguucu uugcaggauc aacaagaaca agcggaguac     1860

uaccaagaaa auccauacua gguuacuuag caaaagauaa aguugaccac agauauaguu     1920

uaaagaaaac ccucaacagu gguuacgaug auucggauug gauguuuuac aacuacggau     1980

ucgcaguugc gcacuacuua uacgaaaaag auaugccaac guucauaaaa augaacaaag     2040

caauacuaaa uacugauguc aaaagcuacg augaaauaau aaagaaacua agugacgacg     2100

ccaauaaaaa uacagaauac caaaaccaua uacaagaacu agcugacaaa uaccaaggug     2160

cgggaauacc ucuaguaagu gacgacuauc uaaaagauca uggauauaag aaagcaucag     2220

aaguuuacuc ugaaaucagc aaagccgcau cauuaacaaa caccucagua acagcugaaa     2280

aaucacaaua uuucaacaca uucacacuaa gggguacaua uacaggcgaa accaguaaag     2340

gagaauuuaa agauugggac gaaaugagca agaaauuaga uggaacucua gaaucuuuag     2400

ccaaaaacuc uuggucagga uacaaaacau uaacggcaua uuucacgaac uauagaguua     2460

caagugauaa uaaagugcaa uaugacguag uauuucacgg aguccucaca gauaacgccg     2520

auauuucaaa uaauaaagcu ccgauagcua aaguaaccgg uccauccaca ggagcaguag     2580

gcagaaacau ugaguucucu gguaaagaua guaaagauga agauggaaaa auagucucau     2640

acgacuggga uuucggagau ggagcaacau caagagggaa aaacucagua caugccuaua     2700

agaaagcggg aaccuauaac guaacccuaa aagucacaga ugacaaggga gcaacggcua     2760

cagaaaguuu uacaaucgaa auuaaaaaug aagacacaac aacaccaaua acgaaggaaa     2820

uggaaccaaa cgacgacauc aaagaagcua acggaccaau aguugaagga guaacaguua     2880

aaggagauuu aaacggauca gaugaugcgg acacuuuuua cuucgauguc aaagaagaug     2940

gagacgucac cauugaauua ccuuauucag gaagcaguaa cuucaccugg uuaguauaua     3000

aagaaggaga cgaucaaaac cacaucgcua gcggcauaga uaaaaauaau ucaaagguug     3060

gaaccuuuaa gucaacaaaa ggaagacacu auguauuuau cuacaaacau gauuccgccu     3120

caaacauauc cuauagccug aauaucaaag gccuaggaaa cgaaaaauua aaagaaaaag     3180

aaaauaacga cagcucagau aaagcaacag uaauuccuaa cuuuaacacu acaaugcaag     3240

guagccuauu gggugacgau aguagagacu auuacagcuu ugaagucaaa gaagaaggag     3300

aaguuaauau agaacuagac aagaaagaug aguuuggagu aaccuggaca uugcacccug     3360

aauccaauau aaaugacaga auuacuuaug gccaagucga cggaaauaaa gucucaaaca     3420

aagugaaacu aagaccgggu aaauauuacc uuuuggugua caaauauagu ggcucaggaa     3480

acuaugaauu aagggucaac aaaugaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  4370
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt6)

<400>  4370
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuucuca aaauaauacu gaaccguggc aaaacaauga      120

aaagaaaaug ccuaaguaaa agacucaugc uggccaucac aauggcuaca auauucaccg      180

ucaacagcac cuuaccuauu uaugcagccg uagacaaaaa uaacgcuacu gccgccguac      240

aaaaugaaag caaaagauac acugucucgu aucuuaaaac acuaaauuac uacgaccuag      300

uagauuuauu aguaaaaaca gaaauagaaa accuaccuga ucucuuucaa uacucaucag      360

augccaaaga auuuuacgga aacaaaacac gaaugucuuu uauaauggau gaaauaggcc      420

gcagagcucc acaauacacc gaaaucgacc acaaaggaau accaacauua guggaagugg      480

uaagagcagg auuuuauuua ggcuuccaca acaaagaacu aaacgaaaua aauaaaagau      540

ccuucaagga aaggguaaua cccucaauau uagcaauaca gaaaaacccc aauuucaaac      600

uaggaacaga agugcaagac aaaaucguca gcgcaacggg acuucuagcc gguaacgaaa      660

cugcuccacc agaaguagua aacaacuuca ccccaauccu acaagacugu auuaaaaaca      720

uagacagaua ugcauuagac gaucuaaagu caaaggcuuu auuuaacguc uuagcugcac      780

cuacuuacga cauaacagaa uaccucaggg caacaaaaga aaaaccggaa aauacaccuu      840

gguacggaaa aauagauggc uucauaaacg aacuaaagaa auuagccuua uacggaaaaa      900

uuaacgauaa uaacucuugg auaauagaua augguauuua ccacauagcu ccguuaggga      960

aacugcauag uaacaauaaa aucggaauag aaacauuaac cgaagucaug aaaguauacc     1020

cauauuuauc aaugcaacac uuacaauccg ccgaccaaau caaaagacac uacgacagca     1080

aagaugcaga aggaaauaaa auaccauuag auaaauucaa gaaagaagga aaagaaaaau     1140

acugcccaaa aaccuauacu uucgacgaug gaaaaguaau aauaaaagcu ggagcaagag     1200

ucgaagaaga aaaaguaaaa cgacucuacu gggcaucaaa agaagucaac ucacaauucu     1260

ucagagucua uggcauagau aaaccgcuag aagagggaaa ccccgaugac auccuaacaa     1320

ugguaauaua caauucacca gaagaguaua aacuaaauag cguauuauac ggauacgaca     1380

caaauaacgg cggaauguac aucgaaccug aaggaaccuu cuucaccuau gagcgagaag     1440

cccaagaaag uacauacacc cuggaagaac uauucagaca ugaauacaca cauuaccuac     1500

aaggacgaua cgccgugcca ggacaauggg ggcgaacgaa auuauacgac aacgacagac     1560

ucacauggua ugaagaaggu ggagcagaau uauucgcagg caguacccgu acaucaggua     1620

uccuaccaag aaaaucuauc gucaguaaca uacacaacac aacuaggaau aaucgauaca     1680

aauuaucaga cacaguacau uccaaauacg gggccuccuu cgaauuuuac aacuacgcgu     1740

gcauguuuau ggauuauaug uauaacaaag auauggguau ucuaaacaaa uuaaacgacc     1800

uagccaagaa uaaugacgug gacggauacg acaacuauau uagggaccua ucaucaaauu     1860

augcauuaaa cgacaaauac caagaccaca ugcaagagag gauagauaau uacgaaaacc     1920

uaacaguacc auuugucgca gacgauuauu uagugcgaca ugcauacaaa aauccaaacg     1980

aaaucuacag ugagauuuca gagguagcaa aacucaagga ugcgaaaucc gaagucaaga     2040

aaagucaaua cuucaguaca uucacgcuaa gaggaucaua uacaggagga gccucaaaag     2100

gaaaauuaga agaccaaaaa gcaaugaaua aauucauaga cgauucauua aagaaacuag     2160

auaccuacag uuggaguggc uauaaaacac ucacugcaua uuucacaaau uacaaaguag     2220

acucaucuaa uaggguaacc uacgauguag uauuccacgg auaccuccca aaugaaggcg     2280

acagcaaaaa cucucuccca uacggaaaaa uaaacgggac auacaaaggu acugaaaaag     2340

agaaaaucaa auucagcagc gaaggauccu ucgacccaga cggaaaaauu guuaguuaug     2400

aaugggacuu cggagaugga aacaaaagua augaagaaaa cccagaacau uccuaugaca     2460

aagucgggac uuacaccgua aaauuaaaag uuacagauga uaaaggcgaa uccaguguau     2520

caacaacaac agccgaaauc aaagacuuaa gcgaaaauaa acuuccagua auauauaugc     2580

acguaccaaa aucuggagca cuuaaccaaa aaguaguauu cuacgguaaa gguacauacg     2640

auccagacgg aucaauagcu ggguaucaau gggacuuugg agacgguuca gauuucucau     2700

cagaacaaaa ucccucccac guauacacaa agaaagguga auacacagug acacuaagag     2760

ucauggauag cagcggccaa augucagaga aaacaaugaa aaucaaaaua acugaucccg     2820

uauauccaau aggcacagaa aaagaaccaa acaacagcaa agaaacagcc agcggaccaa     2880

uaguaccagg cauacccguc aguggaacua uagaaaauac auccgaccaa gacuacuuuu     2940

acuucgaugu aauaaccccu ggagaaguaa aaauagacau aaacaaauua gguuaugggg     3000

gcgcaacaug gguaguguac gaugaaaaua auaacgcagu aaguuaugcu acagacgacg     3060

gccaaaaucu auccggaaaa uucaaagcag acaaaccagg cagauacuau auucaucuau     3120

auauguuuaa cgguagcuac augccuuaca ggaucaacau agaaggaagc guagguagau     3180

agggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  4371
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt6)

<400>  4371
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacguaaau gccuuucaaa acgucuaaug uuggcaauua      120

cuauggcaac aauauuuaca guuaauucca cacuaccaau auaugcagcu guagacaaaa      180

acaaugccac agccgcagua caaaaugaau ccaaaaggua cacugucagu uaucuaaaaa      240

cucuuaacua uuacgaccua guugaccuau uaguaaaaac agaaauagaa aaccuaccag      300

acuuauucca auacucaucu gaugcuaaag aauuuuacgg aaauaaaacc cgcaugaguu      360

uuaucaugga ugaaauagga agacgagcgc cucaauauac ugaaaucgau cacaaaggaa      420

uaccgacgcu aguagaaguu guaagagccg guuuuuacuu aggcuuucac aacaaagaac      480

uaaacgaaau aaauaaacga ucauuuaaag agagaguaau acccagcauc cuugccauac      540

aaaagaaucc aaacuucaaa uuaggaacag agguacaaga caaaauagua uccgccacag      600

gccuauuagc aggaaaugag acagcacccc cugagguagu gaacaauuuc acaccaauau      660

uacaagauug cauuaaaaau auagauagau augcucuaga ugaucuaaaa ucaaaagcac      720

uauucaacgu acuagcagca cccacauacg auauaacaga auacuuacga gcgaccaaag      780

aaaaaccaga aaacacacca ugguacggaa aaauagacgg cuuuauaaau gaguuaaaga      840

aauuagcauu auaugguaaa auaaaugaua auaacagcug gauuauagac aacgggauau      900

aucauauagc accccuagga aaacuacacu caaacaauaa aauaggaaua gaaacauuaa      960

ccgaagucau gaaaguuuau ccuuacuuau ccaugcaaca cuuacaauca gcagaucaaa     1020

uaaaaagaca uuaugauuca aaagacgcag aagguaacaa aauaccccua gacaaauuua     1080

agaaagaagg aaaagaaaaa uauugcccaa aaacauacac auuugacgac gggaaaguaa     1140

ucauaaaagc aggagcgaga gucgaagaag aaaaaguaaa aagacucuac ugggcaucua     1200

aagaaguaaa cucccaauuc uucaggguau auggaauaga caaaccauua gaagaaggaa     1260

aucccgauga cauuuugaca augguaaucu auaauagucc ggaagaauau aaacugaaca     1320

gugucuuaua cggauaugau accaacaacg guggaaugua uauagaacca gagggaaccu     1380

ucuucaccua ugaaagggaa gcccaagaau caacauacac ucucgaggaa cuauuuaggc     1440

acgaauauac acacuauuua caaggacgau acgcaguacc aggacaaugg ggcaggacaa     1500

aacuuuacga uaacgacaga cuaacuuggu augaagaagg uggcgccgaa cuauucgccg     1560

guucaacucg cacaagcgga auauugccac gaaaaucaau cguaucuaac auacacaaca     1620

caacaagaaa uaaccguuac aaacuaucag auacaguuca cuccaaauac ggagcaaguu     1680

uugaauuuua caacuacgcc uguauguuua uggacuacau guauaauaaa gauaugggca     1740

uacuaaauaa acugaacgau uuagcuaaaa acaaugacgu agacggcuac gacaacuaca     1800

uaagagauuu aaguuccaac uaugcacuaa augauaaaua ucaagaucac augcaagaaa     1860

gaauagauaa cuaugaaaau uuaacaguac cuuuuguggc agacgauuac cuuguucgac     1920

acgcauauaa aaaccccaau gagauauauu cagaaauuuc agaaguagca aaauuaaaag     1980

augcaaaaag cgaaguaaag aaaagccaau acuucuccac auuuacccuc cgaggaucau     2040

acaccggcgg agccuccaaa ggaaaacuag aagaccaaaa agcuaugaac aaauucauag     2100

augacucccu aaagaaauua gacacauauu caugguccgg auacaaaacc cuaacggcuu     2160

acuucacaaa uuacaaaguc gacuccucaa auaggguuac auacgacguc guauuucacg     2220

gauaucuccc caaugaggga gacaguaaaa auucccuacc auacgggaaa auaaacggaa     2280

cauauaaagg gacagaaaaa gagaaaauaa aauucucguc ugaaggaucu uuugaccccg     2340

acgggaaaau ugugucauau gaaugggauu uuggagaugg aaauaaauca aaugaagaaa     2400

acccagaaca cagcuaugac aaaguaggca cauacaccgu aaaauuaaaa guaacagacg     2460

acaaaggaga aucaucagua uccaccacca cagcagaaau uaaagaucua ucugaaaaca     2520

aacucccagu aaucuauaug cacguaccua aaaguggcgc ucucaaucaa aaaguaguau     2580

uuuacggaaa aggaacauau gacccagacg gaagcauagc aggguaucaa ugggauuucg     2640

gagauggauc ugauuuuucu ucagaacaaa acccaucgca cguauacacc aagaaaggag     2700

aauauacagu aacacuaaga guuauggauu caucuggaca aaugucugag aaaacuauga     2760

aaauaaaaau aacagaccca guuuauccaa uaggcacaga aaaagaacca aacaacagua     2820

aagaaacagc aucaggacca aucgucccgg gcauaccagu aaguggaaca auagaaaaua     2880

caagcgacca agauuacuuc uacuucgaug uaauaacacc aggcgaaguu aaaauugaca     2940

uaaacaaacu cggauaugga ggagcaacau ggguaguaua ugaugaaaac aauaaugccg     3000

uaucuuacgc cacagacgau ggacaaaacc uaaguggaaa auuuaaagcu gauaaacccg     3060

gacgcuacua cauacaccug uauauguuua acgguucaua caugccauac aggauaaaca     3120

uagaagggag ugugggaaga uaaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  4372
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt6)

<400>  4372
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguua cuuuuauauc auuacuauuc cuauucucau      120

cagcauacag cguacagaac gaaucaaaaa gauacacagu aaguuacuua aaaacguuaa      180

acuacuacga ccuaguagau uuauuaguca aaaccgaaau ugaaaauuua cccgaccuuu      240

uccaauacuc uuccgaugca aaagaauuuu acggcaauaa aacacgaaug agcuucauaa      300

uggaugaaau cgguagacga gcuccccaau acacagaaau agaccacaaa ggaaucccua      360

cauuaguuga aguaguuaga gcaggauucu accuagguuu ucauaacaag gaauuaaaug      420

aaauaaauaa acgaucauuc aaagaacgag uaauaccauc aauacuugca auacagaaaa      480

acccaaacuu uaaacuugga acugaaguuc aagacaaaau agugucagca acaggacucc      540

uagcuggcaa ugaaacagcu ccaccagaag uaguaaacaa cuuuacacca auauuacaag      600

auugcauuaa aaauauagac cgcuacgcuu uagaugaucu aaaaaguaaa gcacuauuua      660

acguacuggc agcaccuacu uacgacauaa ccgaauaccu acgagcaaca aaagaaaaac      720

cugaaaacac ccccugguac ggaaaaauag acggauuuau caacgaacua aagaaauuag      780

cacuuuaugg aaaaauuaac gauaauaauu ccuggaucau cgacaauggc auauaccaua      840

uagcuccacu aggaaaauua cacucaaaca acaaaauagg aauagaaaca cuaacggagg      900

uaaugaaagu auacccauau cuaucaaugc aacaccuaca aucagccgau caaauaaaaa      960

gacauuauga cucaaaagau gcagaaggca acaaaauacc acuagacaaa uucaagaaag     1020

aaggaaaaga aaaauauugu ccgaaaacau acaccuuuga ugauggaaaa guaauuauaa     1080

aagcuggagc aagagucgaa gaagaaaaag uuaaacgauu auauugggca ucaaaagaag     1140

uaaauaguca auuuuuccgc gucuauggaa uagauaaacc ccuugaggaa ggaaauccag     1200

acgacauccu aacaauggua auauauaauu caccugaaga auacaaauua aauucaguac     1260

uauauggaua cgacacaaac aacggaggaa uguacauaga accagaaggu acauucuuua     1320

cauaugagag agaagcacaa gaaagcacau acacucuaga agaacuauuc agacacgagu     1380

acacccacua ccuacaaggu cgauaugcug uaccaggaca auggggaagg acaaaacuau     1440

acgauaauga cagacuaacc ugguacgaag aaggaggagc cgaacuauuc gcaggaagca     1500

cacguacauc agguauacua ccaagaaaau ccauagucag caacauacau aacacgacac     1560

guaacaacag auacaaauua agugacacag uucauagcaa auauggagcu ucauuugagu     1620

uuuauaacua cgcauguaug uucauggauu acauguacaa caaagacaug ggaaucuuaa     1680

auaaacuaaa cgauuuagcu aaaaauaaug auguagaugg auacgacaac uauauacgcg     1740

auuuaagcag uaacuacgca cuaaacgaua aauaccaaga ucacaugcaa gaaaggauag     1800

acaacuacga aaauuuaaca gucccauucg ucgcagacga uuaccuaguc agacacgccu     1860

auaaaaaucc uaacgaaaua uacucagaga uuagcgaggu cgcaaaauua aaagacgcaa     1920

aaagugaagu aaagaaaagu caauauuuca guacauuuac cuuaagaggc ucauauacag     1980

gcggagcaag uaaaggaaaa uuagaagauc aaaaagcaau gaauaaauuc auugaugaca     2040

gccuaaagaa auuagacaca uacucauggu cgggcuacaa aacccuuacc gcuuacuuua     2100

caaacuauaa agucgacagu ucaaacaggg ucacauacga cguuguauuc cacggcuacu     2160

uaccaaauga aggagacagu aaaaacuccc uaccauacgg aaaaauaaau ggaacguaua     2220

aaggaacaga aaaagagaaa auaaaauucu caucagaagg aucauucgac ccggacggaa     2280

aaauuguuuc cuacgaaugg gacuucgggg acgguaacaa aucgaacgaa gaaaauccug     2340

aacauucaua ugauaaagua ggaacauaca caguaaaacu aaaagucaca gaugacaaag     2400

gagaaucguc cguaucuacc acaacagcgg aaauaaaaga uuuaucagaa aauaaacuac     2460

ccguuauuua caugcauguc ccaaaaagcg gagcauuaaa ccaaaaagua guauuuuacg     2520

gaaaaggcac auaugaucca gacggaucaa uugccgguua ucaaugggac uucggagacg     2580

gaagcgacuu caguagugaa caaaaccccu cccauguaua cacaaagaaa ggugaauaca     2640

cagucaccuu aagaguaaug gacucaucag gacagaugag ugagaaaaca augaaaauaa     2700

aaauaaccga ccccgucuau ccaauaggaa ccgaaaaaga accaaauaau ucaaaagaaa     2760

cagcaucagg accaauagua cccggcaucc caguaucugg caccaucgaa aacaccucug     2820

aucaagacua cuucuacuuc gacguaauaa caccagguga aguaaaaauu gauaucaaua     2880

aacuaggaua cggcggagca acauggguag uuuacgacga aaacaacaac gcaguuagcu     2940

acgcuacaga ugacggacaa aaccuaagug ggaaauuuaa agcagacaaa ccuggaagau     3000

auuauaucca ucucuacaug uucaacgguu cuuauaugcc auauagaaua aacauagaag     3060

gcucaguagg aagauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4373
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt6)

<400>  4373
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguua cauucaucag cuuacuauuc cuauucagua      120

gcgccuacag caugaaaaga aaauguuuau ccaaaagacu aaugcuagcu aucacaaugg      180

cuacaauuuu cacagugaac ucuacauuac caauauacgc ugcaguugau aaaaacaacg      240

caacagccgc uagaagaaga agaaaacgag uacaaaacga aagcaaaaga uacaccgucu      300

cuuacuuaaa aacacuaaau uacuacgauc ugguagaccu ucuaguaaaa acugaaauag      360

aaaaucuacc agacuuauuc caauauucaa gcgacgcaaa agaauuuuac ggaaacaaga      420

caagaaugag uuuuauuaug gaugaaauug gacguagagc accccaauac accgaaauag      480

aucacaaagg cauacccacc uuaguggaag uuguaagagc cggguucuac uuaggauuuc      540

auaauaaaga auuaaaugaa auaaauaaac gauccuucaa agaaagaguc auaccaagca      600

uucucgcaau ucagaaaaac ccaaauuuca aacuaggaac cgaaguacaa gauaaaauug      660

uaucagcaac cggauuauua gcugguaacg aaacagcucc cccugaagua guaaauaacu      720

uuacccccau auuacaagau ugcauuaaaa auauagacag auacgccuua gacgaccuaa      780

aaucaaaagc acuauucaau guccucgcug cuccaacaua ugacauaaca gaauaccuua      840

gagcgacuaa ggaaaaaccc gaaaacaccc caugguaugg uaaaauagau gguuucauaa      900

acgaacuaaa gaaacucgca cuauacggaa aaauaaacga caacaauagc uggauaauag      960

acaauggaau auaucauaua gcaccauuag gaaaacuaca uucaaacaau aaaaucggaa     1020

uagaaacauu aacagaagua augaaaguau aucccuauuu aagcaugcaa caucuacagu     1080

cugcggacca aauaaaacgu cauuacgacu cuaaagacgc agaaggaaac aaaauuccac     1140

uagacaaauu uaagaaagaa gggaaagaaa aauacugccc aaaaaccuac acuuuugaug     1200

auggaaaagu aauuauaaaa gcuggagcac gcguagaaga agaaaaagua aaacgauuau     1260

acugggccag uaaagaagug aauagucaau ucuucagagu cuauggaauu gacaaaccuc     1320

uagaagaagg caacccagac gauauacuaa ccaugguuau auauaauucu ccagaagaau     1380

acaaacuaaa uucaguauua uacggauaug auaccaacaa cggagggaug uacauagaac     1440

cugaagguac uuucuuuaca uacgaaagag aagcacaaga aagcacauau accuuagagg     1500

aacuauuuag acacgaauau acacacuacc ugcaaggaag auaugcugug ccaggacaau     1560

ggggacguac uaaacuauac gacaacgaua gacuaacaug guaugaagaa ggaggagcag     1620

aacucuuugc uggcuccacc agaacaagug gaaucuuacc aagaaaaagu auaguaucaa     1680

acauacauaa cacaacaaga aauaacagau acaaacucag cgacacagua cacucaaaau     1740

acggagcuag cuucgaauuu uauaauuacg caugcauguu cauggacuac auguacaaca     1800

aagauauggg aaucuuaaac aaacuaaaug aucuagcgaa aaauaaugau guugaugguu     1860

acgacaacua uauccgugau cucucaucaa acuacgcacu gaacgacaaa uaccaagauc     1920

auaugcaaga acguauagau aauuaugaaa auuuaacugu acccuucgua gcagaugauu     1980

acuugguuag gcaugcauac aaaaauccua augaaauaua cucagaaaua ucugaaguag     2040

ccaaacuaaa agaugcaaaa agugaaguua agaaaagcca auauuuuucc acauuuacau     2100

uacgaggauc cuauacugga ggggccagua aagguaaacu agaagaccaa aaagcaauga     2160

acaaauucau cgaugauucc cuaaagaaau uagauacaua uaguugguca ggcuacaaaa     2220

cacuaacagc cuauuuuaca aauuacaaag uagauucaag caauagaguu acauacgacg     2280

uaguauucca ugguuauuua ccaaaugaag gcgacaguaa aaauucauua ccauacggaa     2340

aaauaaaugg aacauauaaa ggaacggaaa aagagaaaau aaaauucucc ucugaaggau     2400

ccuuugaccc agacggaaaa aucguuagcu acgaauggga cuucggugau gguaacaaau     2460

caaacgaaga aaacccugaa cacagcuacg acaaaguagg aaccuacaca gucaaacuca     2520

aaguaacaga ugauaaaggu gaaucuucug uuucuacgac aacagcagaa aucaaagauu     2580

uauccgaaaa caaacuccca gucauauaua ugcacguacc aaaaucaggu gcacuuaauc     2640

aaaagguugu auuuuaugga aaagguacau augaucccga cggaucaauc gcaggauacc     2700

aaugggacuu cggagacggg ucagauuucu ccucugaaca aaacccaagc cacguauaca     2760

ccaagaaagg agaauauacc guaaccuuac gagucaugga uaguucaggu caaaugucag     2820

agaaaacaau gaaaaucaaa auaacugauc caguauaccc aaucggaaca gaaaaagaac     2880

caaauaauag caaagaaaca gcaaguggac ccaucgugcc aggcauccca guaucgggca     2940

caauagaaaa uacgagcgac caagacuauu ucuacuuuga cgucauaaca ccaggagaag     3000

uaaaaaucga uauaaauaaa cuaggauacg gaggagccac augggucguc uacgaugaaa     3060

acaacaaugc cgugagcuau gcaacagacg auggacagaa ucuuucuggg aaauucaaag     3120

cagauaaacc aggacgauac uauauacacu uauacauguu uaaugguagu uacaugccau     3180

accgaauaaa cauugaagga agcguuggaa gaugaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  4374
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt6)

<400>  4374
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gguaccugga uauuauucgc augccuacua ggcgcagcau      120

ucgccaugcc auuaccacca cacccaggac acccaggaua caucaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc auacccauca uacggauacg      240

aaccaauggg uggauggcua caccaccaaa uaauaccagu acuaucacaa caacacccac      300

caacacacac acuacaacca caccaucaca uaccaguagu accagcacaa caaccaguaa      360

uaccacaaca accaaugaug ccaguaccag gacaacacuc caugacacca auacaacauc      420

accaaccaaa ccuaccaccc ccagcacaac aaccauacca accacaacca guacaaccac      480

aaccacacca accaaugcaa ccacaaccac caguacaccc caugcaacca cucccaccac      540

aaccaccacu accaccaaug uucccaaugc aacccuuacc accaaugcua ccagaccuaa      600

cacuagaagc auggcccuca acagacaaaa caaaaagaga agaagucgac uaaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  4375
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt6)

<400>  4375
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca ccauacccau      180

cauacggaua cgaaccaaug ggaggauggu aaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  4376
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt6)

<400>  4376
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca ccaccaaugc      180

uaccagaccu aacacuagaa gcauggccau caacagacaa aacaaaaaga gaagaaguag      240

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  4377
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt6)

<400>  4377
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa ucaauaagac      240

caccauaccc aucauacgga uacgaaccaa ugggaggaug guaaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  4378
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt6)

<400>  4378
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa ucaauaagac      240

caccaccaau gcuaccagac cuaacacuag aagcauggcc aucaacagac aaaacaaaaa      300

gagaagaagu agacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  4379
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt6)

<400>  4379
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augcuuagua ggagcagcau      120

ucgccaugcc acuaccacca caccccggcc acccaggaua cauaaacuuc ucauacgaag      180

uauuaacacc acuaaaaugg uaccaaucaa ugauacgccc accauacucc ucauacggau      240

acgaaccaau gggcggcugg uuacaccauc aaauaauacc aguaguaucc caacaacacc      300

cacuaacaca cacacuacaa ucacaccacc acauaccagu aguaccagca caacaaccac      360

gaguacgcca acaagcacua augccaguac caggacaaca aucaaugaca ccaacacaac      420

accaccaacc aaaccuacca uuaccagcac aacaaccauu ccaaccacaa ccaguacaac      480

cccaaccaca ccaaccaaug caaccacaac caccaguaca accaaugcaa ccacuccuac      540

cccaaccacc acuaccacca auguucccac uaagaccacu accaccaaua cuaccagacc      600

uacaccuaga agcauggcca gcaacagaca aaacaaaaca agaagaagua gacuaaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  4380
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt6)

<400>  4380
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aaugauaaga ccaccauacu      180

caucauacgg auacgaacca augggaggau gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4381
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt6)

<400>  4381
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguauuaaca ccacuaaaau gguaccaauc aaugauaaga ccaccaccaa      180

uacuaccaga ccuacaccua gaagcauggc cagcaacaga caaaacaaaa caagaagaag      240

uagacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4382
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt6)

<400>  4382
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaucca ggacacccag      180

gauauauaaa uuucucauac gaaguauuaa caccacuaaa augguaucaa ucaaugauaa      240

gaccaccaua cagcucauac ggauacgaac caaugggagg augguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4383
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt6)

<400>  4383
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaucaa ucaaugauaa      240

gaccaccacc aauacuacca gaccuacacc uagaagcaug gccagcaaca gacaaaacaa      300

aacaagaaga aguagacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4384
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt6)

<400>  4384
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaccugga uauuauucgc augccuacua ggagccgcau      120

ucuccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uauuaacccc auuaaaaugg uaucaaaaca ugauaagaca cccauacaca ucauacggau      240

acgaaccaau gggaggaugg cuacaccacc aaauaauacc aguaguaucc caacaaacac      300

cacaaucaca cgcacuacaa ccacaccacc auauaccaau gguaccagca caacaaccag      360

gaauaccaca acaaccaaug augccacuac caggacaaca cucaaugaca ccaacacaac      420

accaccaacc aaaccuacca cuaccagccc aacaaccauu ccaaccacaa ccaguacaac      480

cacaaccaca ccaaccacua caaccccaau ccccaaugca cccaauacaa ccacuacuac      540

cacaaccacc acuaccccca auguucucaa ugcaaucacu acuaccagac cuaccacuag      600

aagcauggcc agccacagac aaaacaaaaa gagaagaagu agacuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4385
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt6)

<400>  4385
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa uaugauaaga cacccauaca      180

caucauacgg auacgaacca augggaggau gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4386
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt6)

<400>  4386
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa caugauaaga cacccaucac      180

uacuaccaga ccuaccacua gaagcauggc cagcaacaga caaaacaaaa agagaagaag      240

uagacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4387
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt6)

<400>  4387
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaucca ggacacccag      180

gauauauaaa uuucucauac gaaguauuaa caccacuaaa augguaucaa aauaugauaa      240

gacauccaua uacaucauac ggauacgaac caaugggagg augguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4388
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt6)

<400>  4388
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa aacaugauaa      240

gacacccauc acuacuacca gaccuaccac uagaagcaug gccagcaaca gacaaaacaa      300

aaagagaaga aguagacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4389
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt6)

<400>  4389
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacuc ggugcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacauac      180

gacacccaua cacaucauac ggauacgaac caaugggagg auggcuacac caccaaauaa      240

uacccguagu aucucaacaa acaccacaau cacacgcacu acaaccacac caccacauac      300

caaugguacc agcacaacaa ccaggaauac cacaacaacc aaugaugcca uuaccaggac      360

aacacucaau gacaccaaca caacaccacc aaccaaaccu accacuacca gcacaacaac      420

cuuuccaacc acaaccagua caaccacaac cacaccaacc acuacaacca caaucaccaa      480

ugcacccaau acaaccauua cuaccacaac caccacuacc accaauguuc ucaaugcaau      540

cacuacuacc agaccuacca cuagaagcau ggccagcaac agacaaaacc aaaagagaag      600

aaguagacua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  4390
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt6)

<400>  4390
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uauucuucgc cugccuacua ggcgcaucac      120

uagcaaugcc acuaccacca cacccaggac acccaggaua uauaaacuuc ucauacgaag      180

uacuaacacc ucuaaaaugg uaccaaaaca ugauaagaca uccauacaca ucauacggau      240

acgaaccaau gggcggaugg uuacaccacc aaauaauacc aguagucucc caacaaacac      300

cacaaucaca cgcauuacaa ccccaccacc acauacccau gguaccagcc caacaaccag      360

gaauaccaca acaaccaaug augccacuac caggacaaca cucaaugaca ccaacacaac      420

accaccaacc aaaccuccca uuaccagcac aacaacccuu ccaaccacaa cccguacaac      480

cacaaccaca ccaaccacua caaccacaau caccaaugca cccaauacaa ccacuacuac      540

cccaaccacc acuaccacca auguucucaa ugcaaucacu acuacccgac cuaccauuag      600

aagcauggcc agcaacagac aaaacaaaaa gagaagaagu agacuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4391
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt6)

<400>  4391
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaucaaaaca ugauaagaca cccaucacua uuaccagacc      240

uaccacuaga agcauggcca gcaacagaca aaacaaaaag agaagaagua gauuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  4392
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt6)

<400>  4392
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggagccgcau      120

ucucaaugcc ccuaccacca cacccaggac acccaggcua cauaaacuuc ucauacgaag      180

accuauaccu agaagcaaua agaauagaca gaacagcauu cguccuaaca ccauuaaaau      240

gguaccaaaa caugauaaga cacccauaca caucauacgg auacgaacca augggaggcu      300

ggcuacacca ccaaauaaua cccguaguau cccaacaaac accacaauca cacgcacucc      360

aaccacacca ucacauaccu augguaccag cacaacaacc cggaauacca caacaaccaa      420

ugaugccacu accaggacaa cacucaauga caccuacaca acaccaccaa ccaaaccuac      480

cauuaccagc acaacaacca uuccaaccac aaccaguaca accacaacca caccaacccc      540

uacaaccaca aucaccaaug cacccaauac aaccacuacu cccacaacca ccccuaccac      600

ccauguucuc aaugcaaucu uuacuaccag auuuaccauu agaagcaugg ccagcaacag      660

acaaaacaaa aagagaagaa guagauuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  4393
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt6)

<400>  4393
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcacaugga uacuauucgc augccuacua ggagcagcau      120

ucuccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacucacccc acuaaaaugg uaccaaaaca ugauaagaca cccaacacca caaucccacg      240

cacuccaacc acaccaccac auaccaaugg uaccagcaca acaaccagga auaccacaac      300

aaccaaugau gccacuacca ggacaacacu caaugacacc aacacaacac caccaaccca      360

accuaccacu accagcacaa caaccauuuc aaccacaacc aguacaacca caaccacacc      420

aaccacuaca accacaauca ccaaugcacc caauacaacc acuacuccca caaccaccac      480

uacccccaau guucucaaug caaucacuau uaccagaccu accacuagaa gcauggccag      540

caacagacaa aacaaaacga gaagaaguag acuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  4394
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt6)

<400>  4394
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

uuucauacga aguacuaacc ccacuaaaau gguaccaaaa caugauaaga caccccuaca      180

caucauacgg cuacgaacca augggaggau ggcuacacca ccaaauaaua ccaguaguau      240

cacaacaaac accacaauca cacgcacucc aaccacacca ccacauacca augguaccag      300

cacaacaacc cggaauacca caacaaccaa ugaugccacu cccaggacaa cacucaauga      360

caccaacaca acaccaccaa ccaaaccuac cacuaccagc ccaacaacca uuccaaccac      420

aaccaguaca accacaacca caccaaccac uacaaccaca aucaccaaug cacccaauac      480

aaccacuacu accacaaccc ccacuacccc caauguucuc aaugcaauca cuacuaccag      540

accuaccacu agaagcaugg ccagcaaccg acaaaacaaa aagagaagaa gucgacuaag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  4395
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt6)

<400>  4395
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagggguag cuagacuacc ucuacucuua ggacuccuau      120

uguuaccacg gccaggaaga ccguuagauc uagcggacua cacauaugau cucgcagaag      180

aagacgacag ugaaccgcua aauuacaaag auccauguaa agcggccgca uuuuugggag      240

auauagcauu agaugaagaa gacuuaagag cauuucaagu acaacaagcu guugaucuaa      300

gaagacacac ggcccgaaaa agcaguauaa aagcagcggu accaggcaac acaagcacgc      360

caucaugcca aaguacaaac ggacaaccac aaagaggggc uugcgggaga uggagaggaa      420

gaagcagaag cagacgcgca gcuacuucaa gaccugaaag aguuuggccu gacggcguaa      480

uaccauucgu aauaggaggc aauuuuacag gaagucagcg cgcaguuuuu cggcaagcaa      540

ugcgccacug ggaaaaacau acuuguguaa cauucuuaga gcgaacagau gaagauuccu      600

auauaguuuu cacauacagg cccugcggau guuguucaua uguaggaaga cgcgggggag      660

gaccacaagc gauaaguaua ggaaaaaauu gugacaaauu cggaauaguu guccaugaau      720

uaggucacgu ugugggauuc uggcacgaac acacacgacc agauagagac agacauguaa      780

guauaguaag ggaaaauaua caaccagggc aggaauacaa cuuuuuaaaa auggaacccc      840

aagagguaga aucacuuggc gaaacuuacg auuucgauag uauaaugcau uaugcuagaa      900

auacauuuuc gagaggaaua uuccuagaca cuauaguacc gaaauacgaa guaaauggag      960

ugaaaccccc aauaggccaa agaacuagac uaucaaaagg agacauagca caggcaagaa     1020

aauuauauaa augucccgcg uguggugaaa cauuacaaga uucuacagga aauuuuucau     1080

cuccugaaua uccuaauggc uauagugcac acaugcauug uguauggcgc auuucaguaa     1140

caccaggaga aaaaauuauu uugaauuuca caagucuaga cuuauacaga aguagauuau     1200

guugguauga cuauguagaa gucagggaug gauucuggag aaaagcuccu cuaaggggaa     1260

gauuuugugg aagcaaauua ccugaaccaa uaguuagcac agauucaaga cuuuggguag     1320

aauuuagaag uaguucaaau uggguaggaa aaggauuuuu cgcaguguau gaagcaauuu     1380

gcgguggaga uguaaaaaaa gacuaugggc acauacaaag cccaaacuau ccugaugauu     1440

auagaccauc aaaaguaugu auauggcgaa uacaaguuag ugaaggguuu cacguaggau     1500

uaacuuuuca auccuucgaa auagaaagac augacucuug cgcauaugau uauuuagaag     1560

uuagagacgg acauagugag aguaguacuc uaaucggaag auacugcggc uaugaaaaac     1620

cugaugacau uaaaagcacu agcucuagau uauggcuaaa auuuguaagu gaugguagca     1680

uaaauaaggc agguuuugca guaaacuuuu uuaaagaggu ugaugaaugu ucgaggccua     1740

auagaggugg uugugaacaa cggugcuuga auacacuagg aagcuacaaa ugcucaugcg     1800

auccaggcua cgaauuagcg ccagauaaaa gaagauguga agcagcaugu ggaggauuuu     1860

ugacuaaacu aaauggauca auaacaaguc cagguuggcc gaaagaauac ccuccuaaua     1920

aaaacuguau uuggcaacuu guagcaccua cucaauauag aauaucauug caauucgauu     1980

uuuucgagac agaaggaaac gacguaugua aauaugacuu uguggaagua agaagugguc     2040

uaaccgcuga uaguaagcua cacggaaaau ucugcgguag ugagaaacca gaaguaauaa     2100

cgucacaaua caauaauaug agaguugaau uuaagaguga caauacaguu ucaaaaaaag     2160

gauuuaaagc acauuuuuuc ucagacaaag augaguguag uaaagauaau ggaggaugcc     2220

agcaagacug cguaaauaca uucggaagcu augaauguca augucgaucc ggcuuuguau     2280

uacacgauaa uaaacacgau uguaaagaag cuggaugcga ucacaaagua acgaguacua     2340

gcggaacaau uacaagccca aauuggccgg acaaauaucc cucaaaaaaa gaauguacuu     2400

gggcaauauc uucuacaccg ggucauagag ugaaauuaac auucauggaa auggacauag     2460

aaucacaacc agaaugugca uaugaucacc uugaaguauu cgaugguaga gaugcuaaag     2520

cuccaguacu gggucgcuuu uguggaagua aaaaacccga gccuguauua gcaacaggau     2580

caagaauguu ccuuagauuc uacuccgaca auucaguaca gagaaaaggu uuccaagcuu     2640

cucacgcaac agaaugugga ggccaagugc gagcggaugu aaaaacaaaa gacuuauauu     2700

cucacgcaca guuuggagac aauaauuauc caggaggugu ggauugugaa uggguuauag     2760

ucgcagaaga aggauacgga guagagcuag ucuuucaaac auuugaggua gaagaagaaa     2820

cugauugugg auacgacuau auggaacucu uugauggaua cgacucaaca gcaccccgau     2880

uagguagaua uuguggaucu ggaccacccg aagaaguaua uuccgcagga gacagcguau     2940

uagucaaguu ccacuccgau gauaccauca cuaaaaaagg auuucaucuu agauauacaa     3000

gcacaaaauu ucaagacacu cuucacagcc gaaaauaggg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  4396
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt6)

<400>  4396
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guagcuggua cuagaugccu acuagcauua cucuuaccac      120

aaguauuacu aggaggagca gcaggauuag ucccagaacu agguagaaga aaauucgcag      180

cugccucauc aggaagaccc agcucacaac cuucagacga aguccuauca gaauuugaau      240

ugagauuacu aucaauguuc ggacuuaaac aaagaccaac accaucaaga gaugcaguag      300

uaccaccaua uaugcuagau uuauauagaa gacacucagg acaaccagga aguccagcuc      360

cagaccauag auuagaaaga gcagcaagua gagcaaacac agucaggagc uuucaucacg      420

aagaaucacu agaagaauua ccagaaacau caggaaaaac cacaagaaga uuuuucuuua      480

accuuaguuc aauaccaaca gaagaauuca ucacaagugc agaacuacaa gucuucaggg      540

aacaaaugca ggacgcacua ggaaauaauu caucauucca ucauagaaua aauaucuaug      600

aaauaauaaa accagcaaca gccaacucaa aauucccagu aacaagacua cuagacacaa      660

gacuaguaaa ccaaaacgca agcagauggg aaagcuuuga uguaacacca gcaguaaugc      720

gauggacagc acaaggucac gcaaaucacg gauucguagu cgaagucgcg caucuagaag      780

aaaaacaagg uguaagcaaa cgacauguaa gaauaaguag aaguuuacac caagaugaac      840

auucaugguc acaaauaaga ccacuccuag uaacauucgg acaugacggu aaaggacacc      900

cacuacacaa acgagaaaaa agacaagcaa aacauaaaca aagaaaaaga cuaaaaucau      960

caugcaaaag acauccguua uauguugacu uuucagaugu aggauggaac gacuggaucg     1020

uagcaccccc aggauaucac gcauucuauu gucauggaga auguccauuu ccauuagcag     1080

aucacuuaaa uagcacaaac cacgccauug uacaaacucu agucaauuca gucaauucaa     1140

aaaucccaaa agcaugcugc guaccuacag aacuaucagc aauuucaaug cuauaccuag     1200

acgaaaauga aaaaguagua cuuaaaaacu aucaagacau gguuguagaa ggauguggau     1260

gcagauaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  4397
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt6)

<400>  4397
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auacccggaa acagaaugcu aaugguagua uuacuaugcc      120

aaguauuacu aggaggagcu agccaugcca gcuuaauucc ugaaacaggc aaaaagaaag      180

uagcagaaau acaaggacac gcaggaggaa gaagaucagg acaaagccau gaacuacuaa      240

gagacuucga agcaacauua cuacaaaugu uuggacuacg acgaagacca caaccuagua      300

aaagcgcagu cauaccagac uauaugagag aucuauaucg cuuacaaagc ggagaagaag      360

aagaagaaca aauacauuca acaggauuag aauacccaga aagacccgca ucaagagcaa      420

auacagugag gucauuccau caugaagaac aucuagaaaa uauaccagga acaucagaaa      480

auucagcauu cagauuuuua uucaauuuaa guucuauacc agaaaacgaa guaauaucau      540

cugcagaacu aagauuauuc agagaacaag uugaucaagg accagacugg gaaagagguu      600

uucacagaau aaauaucuau gaaguaauga aaccuccagc agaaguaguu ccagggcauc      660

uaaucacaag auuacucgau acaagauuag uacaccauaa cguaacacga ugggaaacau      720

uugauguauc accagcaguu cuaagaugga caagagaaaa acaaccgaau uacggauuag      780

caauagaagu uacucacuua caucaaacaa gaacccacca aggacaacau guaagaauau      840

cccgaucauu accacaaggc ucaggaaauu gggcacaacu aagaccacuc cucguaacau      900

uuggacauga cggaagagga caugcucuca ccagaagaag acgagcaaaa agaucaccaa      960

aacaccauag ccaaagagcu agaaagaaaa auaaaaauug cagaagacau aguuuauacg     1020

uugacuucuc agauguagga uggaaugauu ggauaguagc accaccuggu uaccaagcau     1080

uuuauuguca cggagacugu ccauuuccuu uagcagauca cuuaaacagu acaaaucacg     1140

caauaguaca aacucuaguu aacucaguaa acagcucuau accaaaagca ugcugugucc     1200

caacagaacu aucggcaauu ucaauguuau auuuagauga auaugauaaa guaguacuua     1260

aaaauuauca agaaauggua guagaaggau gcggauguag auaaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  4398
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt6)

<400>  4398
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaggauuag gucguagagc acaaugguua ugcugguggu      120

gggguuuacu auguucaugu uguggcccac caccccuaag accaccauua cccgcagcag      180

cggcugcagc cgcaggagga caacuauuag gagauggagg aaguccaggc agaacagaac      240

aaccaccgcc aagcccccaa agcucaucug gauuucuaua cagaagauua aaaacacaag      300

aaaagagaga aaugcaaaaa gaaauacuau cgguauuagg acugccacau cgacccagac      360

cacuacacgg auuacaacaa ccccaaccac ccgcacuucg acaacaagaa gaacaacaac      420

aacaacaaca acuaccaaga ggcgaaccuc caccaggaag auuaaaauca gcaccacuau      480

uuauguuaga uuuauauaac gcauuaucag cagacaauga cgaagacgga gcaucagaag      540

gagaaagaca acaaucaugg ccccaugaag cagcaucaag uucacaacga agacaaccac      600

cuccaggagc ugcucaucca uuaaacagaa aaucacuucu cgccccagga aguggcucug      660

gaggugcaag uccauuaaca ucagcacaag auagcgcuuu cuuaaaugau gcagauaugg      720

uaaugucauu uguaaaucua gucgaauacg auaaagaauu uucaccaaga caacgacauc      780

auaaagaauu uaaauucaau uuaagucaaa uaccugaagg ugaaguaguu acagcugcug      840

aauuucgaau auauaaagac uguguaaugg gaucauuuaa aaaccaaaca uucuuaauau      900

caauauauca aguuuuacaa gaacaucaac auagagauag ugaucucuuu uuacuagaua      960

caagaguagu augggcuagu gaagaagguu gguuagaauu ugacauaaca gcuacgagua     1020

auuuaugggu uguaacacca caacauaaua ugggucuaca acuuagcgua guuacacgag     1080

augguguaca uguacaccca agagcagcag gucuaguagg aagggaugga ccuuaugaca     1140

agcaaccauu caugguagca uucuuuaaag uaagcgaagu ucauguaaga acuacaagau     1200

cagcuucauc aagaagaaga caacaaaguc gaaacagaag uacacaaagu caagauguug     1260

caagaguauc cagugcaucu gauuauaaca guagcgaacu aaaaaccgca uguagaaaac     1320

acgaauuaua cgucagcuuu caagaucuag gauggcaaga uuggauaauc gcaccaaaag     1380

gauaugcagc caauuauugu gauggagaau gcaguuuucc uuuaaaugca cacaugaaug     1440

caacaaauca cgcuauaguu caaacacuug uucacuuaau gaauccugaa uacguaccaa     1500

aaccauguug cgcaccuaca aaauuaaacg caauaucagu acuauacuuu gaugauaauu     1560

caaacguaau acuuaaaaag uauagaaaua ugguaguaag agcauguggu ugucacuaag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  4399
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt6)

<400>  4399
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauguaagau cacuccgagc agcagcacca cacucauuug      120

uagcauuaug ggcaccacua uucuuauuaa gauccgcacu cgcagacuuc aguuuagaca      180

augaaguaca cucaucauuu auacaucgaa gauuacgauc ccaagaaagg agagaaaugc      240

aaagagaaau acucucaaua cuagguuuac cccacagacc aagaccacac cuacaaggaa      300

aacauaauuc cgcaccaaug uucaugcuag aucuauacaa cgcaauggca guagaagaag      360

gaggaggacc aggaggccaa gguuucucau acccauauaa agcaguauuc aguacacaag      420

gaccuccacu agcaucccua caagauucuc acuucuuaac ugaugcagau auggucaugu      480

cauucguuaa cuuaguagaa caugauaaag aauuuuuuca cccaagauau caccaucgug      540

aauuuagauu cgaccuauca aaaauuccag aaggagaagc cguaacagca gcagaauuca      600

ggauuuauaa agacuauauc cgagaacgau ucgacaacga aacauucaga auaucaguau      660

aucaagucuu acaagaacau cucggccgag aaucagacuu auucuuauua gauucgagaa      720

cucuaugggc aucugaagaa ggaugguuag uauuugauau aacagcaaca agcaaucauu      780

ggguaguaaa cccccgacau aaucuaggau uacaauuauc aguagaaaca cuugauggcc      840

aaagcauuaa cccaaaauua gcaggacuaa uaggcagaca ugguccacaa aacaaacaac      900

cauucauggu agcauuuuuc aaagcaacag aaguccauuu cagaaguaua agaucaacag      960

gaaguaaaca aagaucacaa aacagaucaa aaacaccaaa aaaucaagaa gcacuaagaa     1020

uggcuaacgu agcagaaaau agcucuagug accaaaggca agccuguaaa aaacacgaau     1080

uauauguauc auucagagau uuaggauggc aagauuggau cauagcacca gaaggauaug     1140

cagcauauua cugugaagga gaaugugcuu ucccauuaaa cucauacaug aacgcaacaa     1200

aucacgcaau cguacaaaca cucguacacu uuauuaaucc agaaacagua ccaaaacccu     1260

gcugcgcacc cacacaauua aacgcaauau caguacuaua cuuugacgau ucaucaaacg     1320

uaauauuaaa aaaauacaga aacauggucg uaagagcaug ugguugccau uaaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  4400
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt6)

<400>  4400
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagcaucag cagcacuacu augccuacua cuaacagcag      120

cagcauucuc accacaagga cuagcacaac caguaggaau aaacacauca acaacaugcu      180

gcuacagauu cauaaacaaa aaaauaccaa aacaaagacu agaaucauac agaagaacaa      240

caucaucaca cugcccaaga gaagcaguaa uauucaaaac aaaacuagac aaagaaauau      300

gcgcagaccc aacacaaaaa uggguacaag acuucaugaa acaccuagac aaaaaaacac      360

aaacaccaaa acuauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  4401
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt6)

<400>  4401
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuacuaacuu ugauaauauu auuaccaguu guuucaaaau      120

uuucuuuugu gucauuaucu gcaccgcaac acuggaguug uccagaagga acucuagcug      180

gaaauggaaa uucuacaugu guugggccug caccauuucu aauauucagc cauggaaacu      240

caauuuucag aauagauacu gagggaacca acuaugagca acucguuguc gacgcuggag      300

uaucuguaau aauggauuuu cauuacaaug agaaacgcau auacuggguu gacuuagaac      360

gacaauuauu acaaagagua uuucuaaaug gaagcagaca agaaagggua ugcaauauag      420

agaaaaaugu gaguggaaug gcaaucaauu ggauaaauga agaagugaua uggucaaacc      480

aacaagaagg aauuauaaca guaacagaua ugaaaggcaa uaauagccau auacuguuga      540

gcgcccuuaa auauccagcu aacguagcag uagauccagu agaaagauuu auauuuugga      600

guucugaagu cgcaggauca cuauaccgag cugaccuuga uggaguaggu guaaaggcuu      660

uacuagaaac aucagagaaa aucacagcag uaagucuuga cguacuagau aaaagauuau      720

ucuggaucca auauaaccgc gaagggucua auucccuuau auguucaugu gacuacgacg      780

gaggcucagu acauauauca aaacauccga cccaacauaa ucuauuugcu augagccuuu      840

ucggggacag aaucuuuuau ucgacaugga aaaugaaaac aauuuggaua gcaaauaaac      900

acacaggaaa agacauggua agaauuaauu uacauagcuc uuucguaccu uugggagaau      960

uaaaaguagu acauccguug gcacagccua aagcagaaga cgauacaugg gaaccugaac     1020

aaaaauugug caaauugcga aaaggaaacu guucaucgac cguuugugga caagacuuac     1080

aaagucacuu gugcaugugu gcggaaggau augcucuauc cagagauaga aaauauugug     1140

aagaugucaa cgaaugugcu uuuuggaauc auggaugcac acuaggaugc aaaaacacac     1200

cagguucuua uuacuguacc uguccaguag guuuuguuuu acuaccagac gguaaaagau     1260

gucaccagcu aguaucgugu ccacgcaacg uaucugaaug uucucacgau uguguacuua     1320

ccagcgaagg accauuaugu uuuuguccgg agggaagugu acuagaacgu gacgguaaaa     1380

cauguucagg augcucauca ccugauaacg gugguuguag ucaauuaugc gucccacuua     1440

guccuguaag uugggaaugu gacugcuucc caggauauga uuugcaauua gaugagaaaa     1500

gcugugcagc cagcggaccu caacccuuuc uccuuuucgc aaacagccaa gauauaagac     1560

auaugcauuu ugauggaacu gauuauggaa cgcuauuaag ucaacaaaug ggaaugguuu     1620

acgcacuaga ucaugauccu guagaaaaua aaauauauuu ugcucacaca gccuuaaaau     1680

ggauagaacg ggcaaauaug gacgguagcc aaagagaacg acuaaucgaa gaaggaguag     1740

auguuccuga aggauuagca guagauugga ucggaagacg auuuuauugg acggauaggg     1800

gaaaaagccu aauugguaga uccgaccuua auggaaaaag aucaaaaaua auaacaaaag     1860

aaaacauaag ccaaccacgc ggaauugcgg uacauccaau ggcaaaacgg cuauuuugga     1920

cagauacagg aauaaaccca agaauagaaa guucuucuuu acagggacua ggacgucuag     1980

uaauagcaag cuccgauuua auuuggccca gugguauaac gauagacuuu uuaacugaua     2040

aacuauacug gugugaugca aagcaaucag ucauugaaau ggcaaaucua gauggaucua     2100

aaagaagaag acuaacucaa aacgauguag gacacccauu ugccguagca guauuugaag     2160

auuauguuug guucucagau ugggcaaugc caagcguaau gagaguaaau aaaagaacag     2220

gaaaagauag agucagauug caaggaagca uguuaaaacc guccagucuu gucgucguuc     2280

auccccuugc aaaaccaggu gcggauccau gucuauauca aaacggagga ugugaacaua     2340

uuugcaagaa acgguuaggu acugcauggu gcagcugucg agaaggauuc augaaagcga     2400

gcgaugguaa aacauguuua gcacucgaug gacaucaacu acuagcuggc ggagaaguag     2460

accugaaaaa ccaagugaca ccccuugaua uacuuaguaa aaccagagua agugaagaua     2520

auauaacgga aucacaacau auguuaguag cagaaaucau ggugagcgau caagaugauu     2580

gugcacccgu aggauguagu auguaugcaa gaugcaucuc agaaggagaa gacgcaaccu     2640

gccagugcuu aaaaggcuuu gccggcgacg gcaaacugug cucagauauu gaugagugcg     2700

aaaugggugu gcccguuugu ccuccagcgu cauccaaaug uauaaauaca gaaggagguu     2760

auguauguag augcagcgag gguuaucaag gugauggcau acacuguuug gauaucgaug     2820

aaugucaauu aggagaacau ucuugugggg aaaaugcaag uuguacaaau acagaaggag     2880

guuauacuug uaugugugcu ggccguuuaa gugaaccugg cuuaauaugu ccagacagca     2940

cuccgccucc ucaccuaaga gaggaugauc accauuacag cguacgcaau agcgauucag     3000

aaugcccucu aagucacgac ggguacuguc uacaugacgg aguauguaug uacauagagg     3060

cuuuagauaa guaugcaugu aacugugucg uugguuacau aggagaaaga ugucaauauc     3120

gagauuuaaa auggugggaa uuaagacacg cgggacaugg ccaacaacaa aaaguaauag     3180

ucguagccgu cugcguaguu guucuaguaa uguuacuacu acugagucuu uggggugcac     3240

acuauuauag aacacaaaaa cuacuaucga aaaaucccaa aaauccauau gaagaaagca     3300

guagagaugu aaggucaaga cgaccggcug acacagaaga ugggauguca aguugcccac     3360

aaccaugguu uguaguaaua aaagagcauc aagaccuuaa aaacggaggu cagccaguag     3420

cuggagaaga cggucaggcu gcggauggga guaugcaacc aacaucuugg agacaagaac     3480

cucaacugug cggaaugggu acggagcaag gcugcuggau cccugucagc ucagacaaag     3540

gcagcugucc ucaagugaug gaacgaucau uccauaugcc gucauacggg acacaaacgu     3600

uggaaggagg aguggaaaaa ccacauaguc uauuauccgc aaacccauua uggcaacaac     3660

gagcauuaga uccaccucau caaauggaau uaacucaaua aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  4402
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt6)

<400>  4402
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagcaggua gaagaaugga aauguuaugc gcaggaagag      120

uacccgcacu acuacuaugc cuaggauucc accuauuaca agcaguacua ucaacaacag      180

uaauaccaag cugcauacca ggagaaucau cagacaacug cacagcacua guacaaacag      240

aagacaaucc aagaguagca caaguaucaa uaaccaaaug cucaucagac augaacggau      300

acugcuuaca cggacaaugc auauaccuag uagacauguc acaaaacuac ugcagaugcg      360

aagucggaua cacaggagua agaugugaac acuuuuuucu aacaguacau caaccacuau      420

caaaagaaua cguagcacua acaguaauau uaauaauacu auuucuaaua acaguagucg      480

gaucaacaua cuacuucugc agaugguaca gaaacagaaa aucaaaagaa ccaaaaaaag      540

aauacgaaag aguaacauca ggagacccag aacuaccaca aguauaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  4403
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt6)

<400>  4403
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagaaggag aaauaacaac auucacagca cuaacagaaa      120

aauucaaccu accaccagga aacuacaaaa aaccaaaacu acuauacugc ucaaacggag      180

gacacuuccu aagaauacua ccagacggaa caguagacgg aacaagagac agaagcgacc      240

aacacauaca acuacaacua ucagcagaau caguaggaga aguauacaua aaaucaacag      300

aaacaggaca auaccuagca auggacacag acggacuacu auacggauca caaacaccaa      360

acgaagaaug ccuauucuua gaaagacuag aagaaaacca cuacaacaca uacauaucaa      420

aaaaacaugc agaaaaaaac ugguucguag gacuaaaaaa aaacggauca uguaaaagag      480

gaccaagaac acacuacgga caaaaagcaa uacuauuccu accauuacca gucucaagcg      540

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  4404
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt6)

<400>  4404
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guugggguag gaggaggaga cguagaagau guaacaccaa      120

ggccaggagg augucaaaua agcggaagag gagcaagagg auguaauggg auaccaggag      180

cggcagcaug ggaagcugca uuaccaagaa gaagaccuag gagacaucca aguguuaauc      240

caagaucuag agcagcgggg aguccaagaa caagaggaag aagaacagaa gaaagaccaa      300

gugggucaag auuaggagau agagguaggg ggagagcauu accaggugga agauuaggag      360

guagaggaag aggaagagca ccagaaagag ugggaggaag aggaagggga agaggaacag      420

cagcaccaag agcagcacca gcugcaagag gaaguagacc agggccggca ggaacaaugg      480

cagcaggaag uauaacaaca uuaccagcau uaccagaaga cggaggauca ggagcauuuc      540

caccaggaca uuuuaaagac ccaaaaagau uauauuguaa aaacggagga uuuuuucuaa      600

gaauacaucc agauggaaga gucgauggug ugagggaaaa aagugauccg cauauaaaau      660

uacaauuaca agcagaagaa cgaggaguug uaaguauaaa aggaguaugu gcaaauagau      720

aucuagcaau gaaagaagau ggaagauuau uagcaaguaa auguguaaca gacgaauguu      780

uuuuuuuuga aagauuagaa agcaauaauu auaauacuua uagaaguaga aaauauacaa      840

gcugguaugu agcuuuaaaa agaacaggac aauauaaacu aggaaguaaa acaggaccag      900

gacaaaaagc aauacuauuu cuaccaauga gcgcaaaguc auaaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  4405
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt6)

<400>  4405
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uacuaacaug gauacuacca acacuacuau      120

acagaagcug cuuccacaua auaugccuag uaggaacaau aagccuagca ugcaacgaca      180

ugacaccaga acaaauggca acaaacguaa acugcucauc accagaacga cacacaagau      240

cauacgacua cauggaagga ggagacauac gaguaagaag acuauucugc agaacacaau      300

gguaccuaag aauagacaaa agaggaaaag uaaaaggcac ucaagaaaug aaaaacaacu      360

acaacauaau ggaaauaaga acaguagcag ucggaaucgu agcaauaaaa ggaguagaau      420

cagaauucua uuuagcaaug aacaaagaag gaaaacuaua cgcaaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa uuaauacuag aaaaccacua caacacauac gcaucagcca      540

aauggacaca caacggagga gaaauguucg uagcacuaaa ccaaaaagga auaccaguaa      600

gaggaaaaaa aacaaaaaaa gaacaaaaaa cagcacacuu ccuaccaaug gcaauaacau      660

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  4406
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt6)

<400>  4406
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuacuac caucaguagu acuaaaacua uuuuuagcag      120

caguacuauc agcacuagua acuggagaau cacuagaaag auuaagaaga ggacuagcag      180

caggaaccuc aaauccagac ccaccaacag uaagcacaga ccaauuauua ccacuaggag      240

gaggaagaga cagaaaagua agagaccuac aagaagcaga ccuagaccua uuaagaguaa      300

cacuaucauc aaaaccacaa gcacuagcaa caccaaacaa agaagaacac ggaaaaagaa      360

aaaaaaaagg aaaaggacua ggaaaaaaaa gagacccaug ccuaagaaaa uauaaagacu      420

ucugcauaca cggagaaugc aaauacguca aagaacuaag agcaccaagc ugcauaugcc      480

accccggaua ccauggagaa agaugccacg gacuaucacu accaguagaa aaccgacuau      540

acacauacga ucacacaaca auauuagcag uaguagcagu aguauuauca ucaguaugcu      600

uacuaguaau aguaggacua uuaauguuca gauaccacag acgaggagga uacgauguag      660

aaaaugaaga aaaaguaaaa cuaggaauga caaauucaca uuaaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  4407
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt6)

<400>  4407
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uggguaacua aacuuuuacc agcguuauua cuccaacacg      120

uauuacuaca ccuccuauua uuaccaauag cuauaccaua ugcagaagga caaagaaaac      180

gcagaaacac cauacaugaa uuuaaaaaau cggccaaaac aacucuaauc aaaauagauc      240

cagcauuaaa aauaaaaaca aaaaaaguua acacagccga ucaaugugca aaccgcugca      300

cacguaauaa aggccuacca uucacaugca aagcauuugu auuugauaaa gcacguaagc      360

aaugucuaug guuuccauuu aauagcauga gcucuggcgu aaaaaaagaa uuuggacaug      420

aauuugaccu auacgaaaau aaagacuaua uuagaaacug uauuauagga aaaggaagau      480

cauauaaggg cacaguaucc auaacaaaau caggaauuaa augucaacca uggucaucca      540

ugauacccca cgaacauuca uuuuuaccau caaguuauag aggaaaagau uuacaagaaa      600

acuauugccg aaacccaaga ggagaagaag gcggaccuug guguuuuaca ucaaacccag      660

aagucagaua ugaaguuugu gauauacccc aauguucaga aguagaaugu augacaugua      720

auggagaauc auauagaggu cuaauggauc acacagaaag ugguaagaua ugccaaagau      780

gggaucauca gacaccacac cgacauaaau uuuuacccga aagauacccu gauaaaggau      840

uugaugauaa uuacugucga aacccugaug ggcagccaag accauggugu uauacuuuag      900

acccccacac aagaugggaa uauugcgcua uaaaaacaug cgcggauaau acaaugaaug      960

auacagaugu acccuuagaa acuacugaau guauacaagg acaaggugag gguuaucgcg     1020

gcacugucaa uacuauaugg aauggcaucc ccugucaaag augggauuca caauaucccc     1080

augaacauga uaugacacca gaaaacuuua aauguaaaga uuuacgagaa aauuauugcc     1140

guaauccaga ugguucagaa ucucccuggu gcuuuacaac cgauccaaau aucagagucg     1200

gguacuguuc acagauacca aauugcgaca ugucucaugg ucaagauugu uauaggggaa     1260

acggaaaaaa uuauauggga aacuuaucuc aaacuagauc agguuuaacu uguaguaugu     1320

gggauaaaaa uauggaagau uuacacagac auauauucug ggaaccugau gcaagcaaac     1380

uaaacgaaaa cuacuguagg aauccagacg augaugcaca uggcccuugg ugcuauacag     1440

gaaauccauu aaucccgugg gauuauuguc ccauaucgcg augugaaggc gacacaacgc     1500

caacuauagu aaaccuagau cauccaguga uaucaugugc aaaaacuaaa caauuaagag     1560

ucguaaaugg aauaccaaca agaacaaaca uuggauggau gguaucacuc cgauacagaa     1620

auaaacauau auguggagga ucauuaauaa aagaaagcug gguuuuaacc gcaagacaau     1680

guuuuccauc ucgagaccuu aaagacuaug aagcaugguu aggaauacac gacguacaug     1740

guagaggaga cgaaaaaugu aaacaaguac uaaauguuuc ccaacuugua uaugguccag     1800

aagguucaga uuuaguauua augaaauuag cgagacccgc aguuuuagau gauuucguaa     1860

gcaccauaga ccuaccgaau uauggaugua cuauaccaga aaaaacaagu uguaguguau     1920

acggaugggg auauacaggc cuaauaaauu augacggauu acuaagaguc gcacacuuau     1980

auauaauggg aaacgaaaaa uguucacaac aucacagagg uaaaguaaca uuaaaugaaa     2040

gugaaauaug ugcaggagcu gaaaaaauag gcucaggacc gugugaagga gauuauggag     2100

gcccacuagu augugaacag cacaaaauga gaaugguacu aggaguaaua guaccaggcc     2160

gaggaugugc aaucccaaac agaccaggaa ucuuuguuag agucgcuuac uaugcuaaau     2220

ggauacauaa aauaauacua acauauaaag uaccacaauc auaaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  4408
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt6)

<400>  4408
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaaagcag cagcaauugg aauagauuug gguacaacau      120

acaguugcgu gggcguguuu caacacggaa aaguagaaau aauagcaaac gaucaaggaa      180

acaggacaac accaucauac guggcauuua cagacacaga acgauuaaua ggggacgcug      240

cuaaaaacca aguagcauua aacccccaaa acacaguguu cgaugcgaaa aggcuuauag      300

gucggaaauu uggggauccc guaguccaaa gcgauaugaa acauuggcca uuccaaguca      360

uuaaugaugg agauaaacca aaagugcaag uaaguuacaa gggugaaaca aaagcauuuu      420

acccggaaga aauaucaagu augguacuaa cuaaaaugaa ggaaauagcu gaagcauacc      480

uaggauaccc aguaacaaau gcgguaauaa cagugccagc cuacuuuaac gauucgcaac      540

gacaagcaac gaaagacgca ggggucauag ccggucuaaa ugucuuaaga auaauaaaug      600

aaccaacagc agcagcgaua gcuuacggac uagauagaac aggaaaaggu gaaagaaacg      660

uacuaauauu ugauuuggga ggaggaacau uugacguauc gauauuaacc auagaugacg      720

gcauauuuga aguaaaggca acggcaggag acacacaucu gggaggagaa gacuuugaua      780

aucggcuagu aaaucacuuu gucgaagaau uuaaaagaaa acacaagaaa gauauaaguc      840

aaaacaaaag agcaguaaga agacuuagaa ccgccugcga aagagcaaaa agaacacuaa      900

gcucaucaac acaagcaagu uuggaaauag auucauuauu ugaagguaua gacuucuaua      960

cuucaauuac aagagccaga uucgaagaac uauguaguga uuuauuuaga aguacguuag     1020

aaccgguaga aaaagcguua agagaugcua aacuagauaa agcucaaauc caugaucuag     1080

uauuaguagg aggaaguaca agaauaccaa aagugcaaaa auuacuucaa gauuucuuua     1140

acggaagaga ucuaaauaaa ucgauaaauc cagaugaagc gguagcguac ggagcagcag     1200

uacaagcagc aauauugaug ggagauaaaa gugaaaacgu ucaagauuua uuauuacuag     1260

auguagcccc auuaaguuua ggacucgaga cagcuggugg aguuaugaca gcgcuaauaa     1320

aaaggaacuc aacaauacca acaaaacaaa cacaaauauu uacaacauau agugauaauc     1380

aaccaggagu acuaauacaa guauaugaag gagaaagagc gaugacaaaa gacaauaauu     1440

uacuuggaag auucgaacuu aguggaauac caccagcacc acgaggagua ccacaaauag     1500

aaguaacguu ugauauugac gcaaacggaa uacuaaaugu aaccgcuaca gauaaaagca     1560

caggaaaagc aaacaaaaua acuauaacaa augauaaagg uagauuaagu aaagaagaaa     1620

uagaacguau gguacaagaa gcagaaaaau acaaagcaga agacgaagua caaagagaaa     1680

gggucagcgc gaaaaaugca cuagaaaguu acgcauucaa uaugaaaagu gcaguagaag     1740

augaaggacu caaaggaaaa auaagugaag cagauaaaaa gaaagucuua gauaaauguc     1800

aagaagugau aagcuggcua gaugcaaaua cauuagcuga aaaagacgaa uuugaacaua     1860

aaagaaaaga acuagagcaa guaugcaacc caauaauaag uggcuuguac caaggggcag     1920

gaggaccggg gccaggaggc uuuggagcuc aaggaccuaa aggaggaagc gguagcggac     1980

caacaauaga agaaguagac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4409
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt6)

<400>  4409
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaaagcag cagcgauagg aauagauuua gggacaacuu      120

auaguugugu aggaguauuc caacauggaa aaguagaaau aauagcuaau gaccaaggaa      180

auagaacaac uccuaguuau guagcauuua cagacacaga aagacuaaua ggagacgccg      240

cuaaaaauca aguagcccuc aauccacaga auacaguauu cgacgcaaaa agacuuauag      300

guaggaaauu cggagaucca gugguacaaa gcgauaugaa acauuggcca uuucaaguaa      360

uaaaugacgg agauaaacca aaaguacaag uaucauacaa aggagaaaca aaagcauuuu      420

auccugaaga aaucucaagu augguacuaa caaagaugaa ggaaauugca gaagcauauc      480

uuggauaccc aguaacgaac gcaguaauaa caguaccugc cuacuuuaac gacagccaac      540

gucaagcaac uaaagacgca ggaguaauag cuggucuaaa cguacuuaga auuaucaaug      600

aaccaacugc agccgcaauc gcauacggac uagaccgaac gggaaaagga gaaaggaaug      660

uauuaauuuu cgaccuagga ggaggaacau ucgaugucuc uauauuaacu auagacgaug      720

gaauuuuuga aguaaaagca acggcaggag acacgcauuu aggaggagaa gauuucgaua      780

accgucuagu aaaucauuuc guugaagaau uuaaaagaaa acauaaaaag gacauuucgc      840

aaaauaaaag agcagugaga agauuaagaa ccgccuguga aagagcaaaa agaacauuaa      900

gcagcaguac gcaagcaagc cuugaaauag auucacuauu ugaaggaaua gauuucuaca      960

caucaauaac aagagcucga uuugaagaau uauguagcga cuuguucaga ucaacauuag     1020

agccaguaga aaaagcacua agagacgcaa aauuagacaa agcacaaaua caugaccuag     1080

uauuaguugg aggcaguaca cgaauaccaa aaguacaaaa acuucuacaa gacuucuuua     1140

auggaagaga ucuaaauaaa ucaauaaauc cagaugaagc aguagccuac ggugcggcgg     1200

uucaagcagc aauacugaug ggggacaaau cagaaaaugu acaagauuua uuauuauuag     1260

auguggcacc acuaucauua ggauuagaaa cagcuggagg uguaaugaca gcacuaauua     1320

aacgaaacag caccauacca acgaaacaaa cacaaauauu uaccacguac ucggacaauc     1380

aaccgggagu auugauacaa guauacgaag gagaaagagc aaugacuaaa gacaacaauc     1440

uauuaggaag auucgaauua ucaggaauac cgccagcacc aagaggagua ccacaaauag     1500

aaguaacauu cgauauagac gcaaauggca uuuuaaacgu aacagcaaca gacaaaucaa     1560

cagguaaagc aaacaaaaua acaauaacaa augauaaagg aagacuaucu aaagaagaaa     1620

uagaaagaau gguacaagaa gccgaaaaau acaaagcaga agaugaaguu caaagagaac     1680

gugugagugc caagaaugca cuugaaucgu augcguucaa uaugaaaagc gcaguagaag     1740

augagggccu aaaaggaaaa auaucagaag cagacaaaaa gaaagucuug gauaaguguc     1800

aagaaguaau aaguugguua gaugcaaaca cacucgcaga aaaagaugaa uuugaacaua     1860

aaagaaaaga acuagaacaa guaugcaauc caauaauauc aggguuauac caaggagcag     1920

gcggaccagg acccggggga uucggugccc agggaccaaa aggcgguagu ggcagcggac     1980

caaccauuga agaaguagau uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4410
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt6)

<400>  4410
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuacagcaa aaggaauagc aauaggaaua gauuuaggaa      120

caacauauuc guguguugga guauuccaac acggaaaagu agaaaucaua gcaaaugacc      180

aaggaaacag aacaacacca agcuauguag cauuuacgga uacagaaaga uuaauaggag      240

acgcagccaa aaaccaagua gcuaugaauc cacaaaauac aguauucgau gcaaaaagac      300

uaauaggaag aaaauuuaau gacccaguag uacaagcaga uaugaagcua uggcccuucc      360

aaguuauaaa ugaaggaggg aaaccaaaag uucuaguaag uuauaaaggu gaaaauaaag      420

ccuucuaucc agaagaaaua ucaagcaugg uccuaacaaa acuaaaagaa accgcagaag      480

cauucuuagg acauccuguc acuaacgcag uaauaacagu accagcauac uucaacgaua      540

gucaacguca agcaacaaaa gaugcuggag uuauagcagg acuaaaugua cuacgaauaa      600

ucaacgaacc gacagcagca gcuauagcau auggacucga caaaggcgga caaggagaaa      660

gacacgugcu caucuucgac uuaggcggug gcacauuuga uguauccaua cuaaccauug      720

acgauggaau uuucgaagua aaagccacag ccggagacac ccaucuaggg ggagaagauu      780

ucgauaaccg guuaguaagu cacuucguag aagaauuuaa aagaaaacac aagaaagaua      840

uaagucaaaa uaaacgagca guaagaagau uaagaacagc augugaaaga gccaaaagaa      900

cacuuaguag uucaacacaa gcaaacuuag aaauagauuc auuauacgaa ggaauagauu      960

ucuauaccag uauaacaaga gcaagauuug aagaacuaug cgcugauuua uuucgcggaa     1020

cauuagaacc cgucgaaaaa gcauuaagag augcaaaaau ggauaaagca aaaauacacg     1080

acauaguauu agugggaggu agcacgcgaa uaccaaaggu ucaacgauua uuacaagacu     1140

auuuuaaugg cagagaccuc aauaaaagua uaaacccuga ugaagcaguu gcauacggag     1200

cugcaguaca agcagcuaua cugaugggag acaaaucaga aaaaguacaa gaucuccuac     1260

uacuagacgu agcuccacua ucacuggguc uugagacagc gggaggcgua augacagcau     1320

uaauuaaaag gaacucgacc auacccacaa aacaaacaca aauauuuacc acauauucag     1380

auaaccaacc uggagugcuu auucaaguau acgaaggaga aagagcaaug acgaaagaua     1440

auaacuugcu aggaagauuu gaucuaacag ggauuccacc agcaccaaga ggcgugccac     1500

aaauagaagu caccuucgac auagacgcaa acggaauauu aaacgucaca gcaaccgaua     1560

aaucaacagg uaaggucaau aaaauuacaa uaacaaacga uaaaggaaga cuaucaaaag     1620

aagaaauaga aagaauggua cuagaugcag aaaaauacaa agcagaagac gaaguacaaa     1680

gagagaaaau agcagcuaaa aacgcgcuag aaaguuacgc auuuaacaug aaaaguguag     1740

uaucugauga aggauuaaaa ggcaaaauuu cagaaagcga uaaaaauaaa auacuagaca     1800

aaugcaauga acuacuuagu ugguuagaag uaaaucaacu agccgaaaag gaugaauuug     1860

accauaaaag aaaagaacug gaacaaaugu guaaucccau cauaacaaaa cuauaucaag     1920

gaggcugcac aggaccagca uguggaaccg gauauguacc aggacgucca gcaacaggac     1980

caacaauaga agaaguagac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4411
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt6)

<400>  4411
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucagcaagag gaccagcaau ugggauagau cuaggcacaa      120

cuuacucaug cguaggugua uuccaacacg gaaaaguaga aauuauagca aacgaucaag      180

ggaacagaac aacaccaagu uauguagcau uuacagacac ugaaagauua auaggugacg      240

cagcuaaaaa ucaaguagca augaacccua caaacacaau uuuugacgca aaacgacuaa      300

ucggaagaaa auucgaagac gcaacaguac aaucagauau gaaacauugg ccguucagag      360

uaguaagcga aggagggaaa ccaaaaguac agguugaaua caaaggagaa acaaaaacuu      420

ucuucccaga agaaauuagu aguauggucc ucacaaaaau gaaagaaaua gcagaagcau      480

accuuggagg aaaaguucac ucagcaguaa uuacaguacc agcauacuuc aacgauuccc      540

aaagacaagc aacgaaagac gccgguacaa uaacaggauu aaacguguua agaauuauaa      600

acgaaccuac cgcagcagcc auagcguaug gauuagauaa gaaaggaugu gcaggaggag      660

agaaaaaugu auuaauauuu gacuuaggcg gugggacauu ugauguaagu auacugacaa      720

uagaagaugg gauauuugaa gucaaaucga cagcaggaga cacacauuua gggggagaag      780

acuuugacaa cagaauggua agccaucuag cagaagaguu caaaagaaaa cacaagaaag      840

acauaggacc caauaaaaga gcugucagga gacuuagaac agcaugcgaa agagcaaaaa      900

gaacauuauc aaguucaaca caagcaagua uagaaauaga uucgcuauau gaaggaguug      960

auuucuauac aaguauaaca agagcaagau uugaagaacu aaacgccgau cuauuuagag     1020

gaacauuaga accgguugaa aaagcacuua gagacgcaaa auuggauaaa ggccaaauac     1080

aagaaauugu ucuaguagga ggaaguacac gcauuccaaa aauacaaaaa cuauuacaag     1140

acuuuuucaa uggaaaagaa cucaauaaau caauaaaccc ugaugaagcg guagcguaug     1200

gugcagccgu acaagccgca auauuaaucg gagacaaaag ugaaaacgua caagaccuac     1260

uauuguuaga uguaacacca uuaucacucg gaauugaaac agcuggagga guaaugacac     1320

cacucauaaa aagaaauaca accauuccca caaaacaaac acaaacauuc acaacguaca     1380

gcgauaacca aaguagcguc cuaguacaag uauaugaagg cgaaagagca augaccaaag     1440

acaacaaucu auuaggaaaa uucgacuuaa caggaauacc uccagcacca aggggaguac     1500

cacaaauaga aguuacauuu gacauagaug cuaacggaau auuaaacgua acagcagcag     1560

auaaaagcac aggaaaagag aauaaaauaa caauuacaaa cgauaaagga agacuaagca     1620

aagacgauau agauagaaug guacaagaag cagaaagaua uaaaagcgaa gacgaagcua     1680

acagggaucg agucgcagcc aaaaaugcau uggaaagcua uacauacaau auaaaacaaa     1740

cuguagaaga ugaaaaauua agaggaaaga uaagugaaca agauaaaaau aaaauuuuag     1800

acaaauguca agaaguuaua aacugguuag auagaaacca aauggccgaa aaagacgagu     1860

acgaacauaa acaaaaagaa cuagaaagag ucuguaaucc cauaauuagc aaauuauacc     1920

aaggaggacc cggaggugga aguggaggag gaggaucagg agcaagcgga ggcccaacaa     1980

uagaagaggu ugauuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  4412
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt6)

<400>  4412
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgugguag guauagaucu uggauuccaa ucauguuacg      120

uugccguagc aagagcagga ggaauagaaa caauagccaa cgaauacagu gacagaugua      180

caccggccug cauauccuuu ggaccuaaaa acagaucaau cggcgcagcc gcaaaaucac      240

aagugauuuc aaaugcuaaa aacacagugc aagguuucaa aagauuccac ggacgagcau      300

uuagcgaccc auuuguugaa gcagaaaaau caaacuuagc uuaugauauc guacaauuac      360

ccacaggacu aacagguaua aaagucacau auauggaaga ggaaagaaac uucacaaccg      420

aacaaguaac cgcgaugcua uuaucaaaac ucaaagaaac agcagaaucc gucuuaaaga      480

aaccugucgu ugacugugua guaucaguac ccugcuucua cacagacgca gaaagaagau      540

ccguaaugga ugccacacaa auagcugguc ugaauugcuu acgacuaaug aaugaaacga      600

cggcaguugc auuagcuuac ggaauauaua aacaagacuu acccgcacua gaagaaaaac      660

caagaaacgu cguauuugua gauauggguc acagugcaua ucaagugucc guaugugcuu      720

uuaacagagg uaaacuaaaa guauuagcaa cagcuuuuga uacuacuuua ggcggacgaa      780

aauuugauga aguucuagua aaucauuuuu gcgaagaauu ugguaagaaa uacaaacucg      840

auaucaaauc aaaaauacgu gcauuauuac gacuuucaca agaaugugaa aaacuaaaga      900

aauuaaugag ugcaaacgca agcgaccugc cuuuaucuau agaauguuuc augaacgaug      960

uagauguauc gggcacaaug aacagaggua aauuccucga aaugugcaac gaucuguuag     1020

caagaguaga accaccacua cgaaguguau uagaacaaac aaaacuaaag aaagaagaca     1080

uuuaugcagu agaaauaguu ggaggggcaa cacgaauacc agcgguaaaa gagaaaauuu     1140

caaaauucuu uggcaaagaa uuaucaacua cacuuaaugc agaugaagcc guaacuagag     1200

gaugugcacu ccaaugugca auauuaucac cagcuuucaa aguaagagaa uuuagcauaa     1260

cagauguagu accauaccca auuucacuga gauggaacuc accagcagaa gaagggucau     1320

ccgacugcga aguauucagu aaaaaucaug cugccccuuu uucaaaagua cuaacauucu     1380

auagaaaaga accuuuuacc cuagaagcau acuauucauc accccaagau cuuccauacc     1440

ccgauccagc aauagcccaa uuuagcgugc aaaaaguuac accucaaagu gauggaucaa     1500

gcaguaaagu uaaaguaaaa guccguguga acguucaugg uauauuuagu guaucuucag     1560

ccagccuagu agaaguacac aaaagcgaag aaaaugaaga accaauggaa acggaucaaa     1620

augcuaaaga agaagagaaa augcaaguag accaagaaga accacaugua gaggaacaac     1680

aacaacaaac acccgcagaa aacaaagccg aaagugaaga aauggaaaca ucucaagcag     1740

gaucaaagga uaagaaaaug gaucaaccuc cucaagcgaa gaaagcaaaa guaaaaacau     1800

cuacagucga ucuuccaaua gaaaaccaac uuuuauggca aaucgauaga gaaauguuaa     1860

accuauauau agaaaacgaa ggaaaaauga uaaugcaaga caaauuagaa aaagaaagaa     1920

acgacgcuaa aaacgcagua gaagaauaug uuuaugaaau gagagauaaa cugagcggag     1980

aauacgaaaa auucguaagc gaagacgauc gaaauucauu cacccuaaaa cuugaagaca     2040

cugaaaacug gcucuacgaa gauggagaag accaaccaaa acaaguauac guagauaaac     2100

uagcagaacu gaaaaaccua ggacaaccaa uaaaaauaag auuccaagaa agugaagaac     2160

guccuaaauu auucgaagaa cuaggaaaac aaauacaaca auauaugaaa aucauaucaa     2220

guuuuaaaaa caaagaagau caauacgacc acuuagaugc cgcagacaug acaaaaguag     2280

aaaaaucuac uaacgaagcc auggaaugga ugaauaauaa auuaaaccuc cagaacaaac     2340

aaucgcuaac aauggaucca guggucaaau caaaagaaau agaagcaaaa auuaaagaac     2400

uaacaaguac uugcucacca aucauaagca aaccaaaacc caaagucgaa ccaccaaaag     2460

aagaacagaa aaacgcagaa caaaauggac caguagacgg ccaaggugac aacccaggac     2520

cacaagcagc ggaacaaggu acugacacag caguacccuc agacagugau aagaaacuac     2580

cagaaaugga uauagacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  4413
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt6)

<400>  4413
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaguagucg gaauugaccu uggauuuuua aacugcuaca      120

uagcaguagc uaggucagga ggaaucgaaa caauagcaaa cgaauauagc gauagaugca      180

ccccugccug cauaucauua ggaucacgca cuagagcaau cgggaacgca gccaaaucac      240

aaauaguuac aaacguaaga aauacaaucc acggauucaa aaaacuacac ggcagguccu      300

uugaugaucc aauaguacaa acggaaagaa uaagacuacc cuacgaacug caaaaaaugc      360

ccaauggaag ugcaggcguc aaagucagau aucuagaaga agaaagaccu uuugcaauag      420

aacaaguaac cggaauguua uuggcuaagc uaaaagaaac uucagaaaac gcauuaaaga      480

aaccuguagc agauuguguu auaucaauac caucguuuuu cacagaugca gaacgaagau      540

caguaauggc agcagcacaa guagccggcc uaaacugucu ucgacuaaug aaugaaacaa      600

cugcaguugc ccuagcuuau ggaauuuaua aacaagauuu accuccucua gacgaaaaac      660

ccaggaacgu aguauucaua gauauggguc auagugcaua ucaaguucua gugugugcau      720

uuaauaaagg aaaauuaaaa guccuagcaa caacauucga uccguaucua ggagggcgaa      780

acuucgauga ggcacuggua gacuacuuuu gugacgaauu caaaacgaaa uacaagauua      840

acguaaaaga aaacagcaga gcucuucuaa ggcuauacca agaaugugaa aaacucaaaa      900

aauuaauguc cgcuaaugcc ucagaccuac cacuaaauau agaauguuuc augaaugauu      960

uagauguguc aaguaaaaug aacagagcac aauuugaaca auuaugcgca ucauuacuag     1020

cucgaguaga accaccauua aaagccguaa uggaacaagc uaauuuacaa cgagaagaua     1080

ucucaucaau agaaaucguu ggaggagcca ccagaauucc agcgguaaaa gaacaaauua     1140

cuaaauuuuu ucuuaaagac aucucaacaa cacuaaaugc ugacgaagca guugcccggg     1200

gaugcgcccu ccaaugugca auacuuagcc cugcauuuaa aguacgagaa uuuucaauaa     1260

cagacuuagu uccauauucg aucacauuaa gauggaaaac aucauucgaa gacggcagcg     1320

gcgaauguga aguauucugc aaaaaccacc cagccccuuu uagcaaagua auaacauuuc     1380

auaaaaaaga accguuugaa uuagaagcau uuuacacaaa cuuacacgaa guaccauacc     1440

cugaugcacg aauagguagc uuuacuauac aaaacguauu cccacaaucc gauggcgaca     1500

gcucaaaagu uaaaguaaaa gucagaguaa acauacaugg aauuuucucu gucgcaucag     1560

caucuguuau cgaaaaacaa aaucuagaag gggaccauuc cgacgcccca auggaaaccg     1620

aaacaagcuu uaaaaaugaa aacaaagaca auauggauaa aaugcaagua gaucaagaag     1680

aaggacauca aaaaugccau gcugagcaua caccagaaga agagauagac cacacugggg     1740

caaaaacaaa aucagccguu ucagauaaac aagauagauu aaaucaaaca cuaaaaaaag     1800

gcaagguaaa aucuauugau uuaccaaucc aauccucacu cugcagacaa uuaggacaag     1860

aucuauuaaa uagcuauaua gaaaaugaag gaaaaaugau caugcaagac aaacuagaaa     1920

aagaaagaaa cgacgccaaa aaugcaguug aagaauacgu auaugauuuc agggaccgac     1980

uaggaaccgu uuaugaaaaa uuuauaacgc cagaagaccu uucaaaacua agugcaguau     2040

uagaagacac agagaacugg uuauaugaag auggagaaga ccaaccaaaa caaguauacg     2100

uugacaaauu acaagaacua aagaaauacg gacaaccaau acaaaugaaa uacauggagc     2160

acgaagaacg uccaaaagca cuaaacgacc uaggcaaaaa gauccaacuu guaaugaaag     2220

uaauagaagc uuauagaaau aaagaugaac gguaugacca ucuugacccc acagaaaugg     2280

aaaaaguuga aaaaugcaua agcgacgcaa ugagcuggcu caacagcaaa augaacgcac     2340

aaaacaaauu aucacuaaca caagauccag uaguaaaagu cagugaaaua guagcaaaau     2400

caaaagaacu agacaauuuc uguaauccaa uaauauacaa acccaaacca aaagccgaag     2460

uccccgaaga caaaccaaaa gcaaacucag aacauaaugg uccaauggau ggacaaucug     2520

gaacagagac aaaaucagac ucaacuaaag auucauccca acauaccaag aguagcgggg     2580

aaauggaagu cgacuaggga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  4414
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt6)

<400>  4414
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauuaaguu ugguggcagc aaugcuauua uuauuaagcg      120

cugcaagagc agaagaagag gauaaaaaag aagauguugg uacggugguu ggaauugacc      180

uuggaacaac auacagcugu gucggaguau uuaaaaaugg aagaguugaa auuauagcua      240

acgaucaggg gaauagaaua acaccaaguu acguagcauu cacaccagag ggagaaagau      300

uaaucggaga cgcagcaaaa aaccaacuua cuaguaaucc agaaaauaca guauucgaug      360

caaaaagauu aauaggaaga acauggaacg acccuuccgu acaacaagau aucaaauucc      420

uaccauuuaa aguuguagaa aaaaagacaa aaccauacau acaagucgau auaggaggag      480

gacaaacaaa aacauuugcg ccagaggaaa ucagugcaau gguauuaacu aaaaugaaag      540

agacagcaga agcauacuua gguaaaaaag uaacacacgc aguagucaca guaccagcau      600

auuuuaacga cgcacaaaga caagcaacaa aggaugcagg aacaaucgca ggauuaaacg      660

uaaugagaau aauaaaugag ccaacagcag cagcaauugc auauggauua gacaaacgag      720

aaggugagaa aaacauccug guauucgacu uaggaggggg cacauuugac guaaguuuau      780

uaacuauaga uaauggagua uuugaaguag uagcaacaaa cggugacaca cauuuaggag      840

gagaagauuu cgaucagaga guaauggaac auuuuauaaa auuauacaaa aaaaaaacag      900

gaaaagaugu aaggaaagac aauagagcag ugcaaaaacu uaggagagaa gucgaaaaag      960

caaaacgagc ccuaaguagc caacaucaag caagaauaga aauagaaagc uuuuaugaag     1020

gggaagacuu cagugaaaca cuuacgagag caaaauuuga agaauuaaac auggaccuau     1080

uuagaagcac aaugaaaccu guacaaaaag ugcucgaaga uucagaccua aaaaaaagcg     1140

acauagauga gauugucuua guaggaggaa guacaagaau uccaaaaauc caacaacuag     1200

uaaaagaauu uuucaaugga aaagaaccua guagaggaau aaacccagac gaagcaguag     1260

cauauggagc ugcaguacaa gcuggaguuc uaaguggcga ccaagacaca ggagacuuag     1320

uauuacuaga cguauguccg uuaacauuag gaauagaaac aguaggagga guaaugacca     1380

aauugauacc uaggaacacu guuguaccaa cgaaaaaauc acaaauauuu aguacagcau     1440

cagauaacca accaacugua acuauaaaag uauacgaagg agaaaggccu cuaacaaaag     1500

acaaucaccu ucugggaacc uuugaucuca caggaauacc accagcacca cggggaguac     1560

cgcaaauaga aguaacauuc gaaauagacg ucaacgguau ucuaagagua acggccgaag     1620

auaaaggaac aggaaacaag aauaagauaa cuauuacaaa ugaccaaaau cgauuaacuc     1680

cagaagaaau agaacgaaug gucaacgacg cagaaaaauu ugccgaagaa gauaaaaaau     1740

uaaaagagag aauagauacu cgaaacgaac uagaaaguua cgccuacuca cucaaaaacc     1800

aaaucgggga uaaagaaaag uuaggaggua aauuaucaag ugaagauaaa gaaacaaugg     1860

aaaaagcagu cgaagaaaaa auugaauggc uagaaucaca ccaagacgca gauauagaag     1920

auuucaaagc aaaaaaaaaa gaauuagaag aaauuguaca acccauaauu aguaaauuau     1980

auggaagugc agggccacca ccaacaggcg aagaagacac agcagaaaaa gaugaauuau     2040

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  4415
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt6)

<400>  4415
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcaccaa gagaacuagc gguaggaaua gauuuaggaa      120

caacuuacuc auguguagga guauuucaac aaggaagagu agaaauauua gcaaaugacc      180

aaggaaauag aacaacaccc ucauacguag ccuuuacaga caccgaacga uuaguaggag      240

augcagcaaa aagccaagca gcacucaacc cacauaauac ggucuuugac gcaaaaagau      300

uaauaggccg aaaauuugcg gauacuacag uacaaaguga uaugaaacac uggcccuuuc      360

gaguaguauc ugaaggagga aaaccgaagg uaagaguaug uuaucgagga gaagacaaaa      420

cauucuaucc agaagaaaua ucuucuaugg uauugucgaa aaugaaagaa acggcugaag      480

cguaucuagg acaaccagua aaacaugcag uaauaacugu accagcuuac uuuaaugaua      540

gccagagaca agcaacaaaa gaugcaggag ccauagcagg auuaaaugua uugaggauaa      600

uaaaugaacc aacugcagcc gcaauagcau acggguuaga ccgaagagga gccggugaaa      660

gaaaugucuu aauauuugau uugggcggag gaacauuuga uguaagugua uuaucaauag      720

acgcaggagu uuuugaaguc aaagcaacgg caggagacac acauuuagga ggggaagacu      780

uugauaauag gcuaguaaau cauuucaugg aagaauuucg aagaaaacac ggaaaagauu      840

uaucuggaaa uaaacgagcu uuaagaaggu uaagaacagc cugugaaaga gcaaaaagaa      900

cauuaucauc aaguacacaa gcaacauuag aaauugacuc acucuucgaa ggagucgacu      960

ucuauacauc aauaacacga gcaagauuug aagaacuaug cucagaucua uuucgaucaa     1020

cauuagaacc aguggaaaaa gcauugcggg augcgaaauu agacaaagca caaauacaug     1080

acguaguuuu aguaggcggc ucaacaagaa uaccaaaagu gcaaaaacua uuacaagauu     1140

ucuucaacgg gaaagaauua aacaaaucaa uuaauccgga ugaagcugua gcuuauggag     1200

cagcaguuca agccgccguc uuaaugggag acaaaugcga aaaaguucaa gauuuauuac     1260

uacuagaugu ggcaccacuc ucucuugguc ucgaaacagc gggaggaguu augacuacgu     1320

uaauccaaag aaaugcaaca auuccaacaa aacaaaccca gacauucaca acauacucug     1380

auaaucaacc aggagucuuu auacaaguuu acgaaggcga acgagcaaug acaaaagaua     1440

auaauuuauu gggaagauuu gaacuuucag gaauaccccc agcaccuaga ggaguaccuc     1500

aaauagaagu aaccuucgac auagacgcua auggaauacu uagcguaacu gcaacugaua     1560

gaaguacagg aaaagcaaac aaaauaacaa uaacaaacga uaaaggccga cuaagcaaag     1620

aagaaguaga aagaauggua caugaagcug aacaauacaa agccgaagau gaagcacaac     1680

gagauagagu ugcagcuaaa aauagucuag aggcacaugu auuucaugua aaaggcagcc     1740

uacaagaaga gagcuuaaga gacaaaauac cagaagaaga cagaagaaaa augcaagaua     1800

aguguagaga aguauuggca ugguuagaac auaaucaauu agcagaaaaa gaagaauaug     1860

aacaucaaaa acgagaauua gaacaaauau gucgaccaau auuuucaagg uuauauggag     1920

gcccaggagu accaggggga aguucaugug guacacaagc aagacaaggu gauccgucaa     1980

caggaccaau caucgaagaa guagacuaag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  4416
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt6)

<400>  4416
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcaccaa gagaauuagc uguaggaaua gacuuaggaa      120

caacauauuc cuguguagga guauuucaac aaggaagagu agaaauuuua gcaaaugauc      180

aaggaaauag aacaacacca ucauauguag cauuuacuga uaccgaaaga uuagucggag      240

augcagcaaa gucacaagca gcauuaaauc cucacaauac aguuuuugau gcaaaaagau      300

uaauaggaag aaaauucgcu gauacaacag uacaaagcga caugaaacau uggccauucc      360

aaguuguaag cgaaggugga aaaccaaaag uacgaguaug uuauagagga gaagacaaaa      420

cauucuaccc cgaagaaaua ucaaguaugg uucuaucaaa aaugaaagaa acagcagaag      480

cauauuuagg acaaccaguu aaacaugcag uaauaaccgu uccaacauau uuuagcaaua      540

gucaaagaca agcaacuaaa gaugcaggag caauagcagg acuuaaagua cugccaauaa      600

uaaaugaagc aacagcagca gcaauagccu auggccuaga cagaagagga gcuggaaaaa      660

gaaacguauu aauauuugau uuaggaggag gaacuuuuga uguaagugua uuaaguauug      720

acgcaggcgu uuuugaagua aaagcaacug cuggugauac ucacuugggu ggagaagauu      780

uugauaauag auuaguaaau cauuuuaugg aagaauuuag aagaaaacac ggaaaagauc      840

uaaguggaaa uaaaagggca uugagaagau uaagaacagc augugaaaga gcaaaaagaa      900

caccuagcuc aaguacacaa gcaacgcuag aaauagauuc auuauucgaa ggaguagauu      960

uuuauaaauc aaucacaagg gcaagauuug aagaauuaug cagugacuua uucaggagca     1020

cauuagaacc aguagaaaaa gcauuaagag augcaaaauu agauaaagca caaauacaug     1080

auuuugugcu aggaggggga uuacauucac auccacaagg agcagaaguu gcagcaggau     1140

uauuacaaag acaaggagca gaacaagaac accaaccaua aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  4417
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt6)

<400>  4417
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaaagggc cagcaguagg aauagauuua gguaccaccu      120

acagcugugu aggaguauuc caacacggaa aaguggaaau aauagcaaau gaccaaggca      180

auaggacaac accaucauac guugcauuca cagauaccga gcgacuaauu ggagaugcag      240

cuaaaaauca aguagcaaug aauccaacaa auacgguauu ugacgcaaaa agacuaauag      300

gcaggagguu ugaugacgca guuguacaaa gcgauaugaa acacuggcca uuuaugguag      360

uaaaugaugc uggaagacca aaaguacaag uagaauacaa aggcgaaacu aaaaguuucu      420

accccgaaga aguaucuuca augguauuaa caaaaaugaa agaaaucgca gaagcauacu      480

uaggaaaaac gguuacaaac gcaguaguaa caguaccagc auauuuuaac gacucccaaa      540

ggcaagcaac aaaagacgcu gggacaauug ccgggcuuaa uguauuaaga aucauaaaug      600

aaccaacagc agcagcaaua gccuacggau uagauaagaa aguaggugca gaaagaaacg      660

uauuaauauu ugacuuaggc gguggaacau uugauguauc aauauuaaca auagaagacg      720

gaauauuuga aguaaaaucu acagcuggag acacacaccu aggaggagaa gauuucgaua      780

acagaauggu aaaucauuuu auagccgaau uuaaaaggaa acauaagaaa gauauaagug      840

aaaauaaaag agcaguaaga agauuaagaa cagcaugcga gcgagcgaaa aggacuuuau      900

caucgagcac acaagcaagc auagaaauug auagccuaua ugaagguaua gacuuuuaca      960

caucaauaac aagagcccga uucgaagaau uaaacgcaga ucuauuuaga ggaacguuag     1020

acccaguaga aaaagcauua agagaugcaa aauuagauaa aagccaaaua caugacaucg     1080

uauugguugg aggaucuaca agaauaccua aaauacaaaa auuacuacaa gacuucuuua     1140

acggcaaaga auuaaacaaa ucaauaaauc cagacgaagc aguagcguau ggugcggcgg     1200

uacaagccgc uauauuaucc ggagacaaaa gugaaaacgu acaagaucua cuauuacuag     1260

acguaacacc ccuaucauua ggaauugaaa cagcaggagg aguaaugaca guuuuaauaa     1320

aaagaaauac aacaauacca acuaaacaaa cccaaacauu uacaacuuac agugacaauc     1380

aaccaggagu gcucauacaa guuuacgaag gagaacgagc aaugacaaaa gacaacaauc     1440

uauuaggaaa auuugaacua accggaauac caccagcacc uagaggcgug ccacaaauag     1500

aagucacauu ugacauagau gcaaauggaa uacuaaacgu cagcgcaguc gauaaaucaa     1560

caggaaaaga aaacaaaaua accauaacaa acgacaaagg acgccugagc aaagaagaua     1620

ucgaacgaau gguacaagaa gcagaaaaau auaaagcgga ggacgaaaaa caacgagaca     1680

aaguaagcag uaaaaacagc uuagaaucau augcauuuaa uaugaaagca acuguagaag     1740

acgaaaaauu acaaggaaaa auaaacgaug aagauaaaca gaaaauacua gacaaaugua     1800

acgagauaau aaauuggcug gacaaaaauc aaacggcaga aaaagaagaa uuugaacauc     1860

aacaaaaaga gcuugaaaaa guuuguaauc caauaauaac aaaacuauau caaagugcag     1920

gaggaaugcc aggaggaaug cccggaggau ucccuggagg aggcgcaccc ccaaguggag     1980

gagccaguuc aggcccaaca auagaagaag uagauuaggg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  4418
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt6)

<400>  4418
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaucagcaa gcagagcagc agcagcaaga cuugugggag      120

cagcagcauc aagaggaccu acagcagcaa ggcaucaaga uucguggaau ggguuaagcc      180

augaggcguu uagacuugug ucuaggagag auuacgccag cgaagcaauu aaaggugcgg      240

uuguaggaau agaucuagga acgacaaacu cauguguagc agucauggaa ggaaaacaag      300

caaaagugcu agaaaaugca gaaggcgcaa gaacaacacc aucaguaguu gcauuuacag      360

cagauggaga aagguuaguu gguaugccag caaaaagaca agcaguaaca aauccgaaca      420

auacauuuua cgcuacaaaa agguuaauag gaagaagaua cgaugaccca gaagugcaaa      480

aagauauuaa aaauguaccu uuuaaaauag ucagagcauc uaauggugau gcauggguag      540

aggcccacgg aaaacucuac ucuccaaguc aaauaggagc cuucguauua augaagauga      600

aagaaacagc ugaaaauuau uuaggacaca cagcgaaaaa ugcaguaaua acgguaccag      660

cauacuucaa cgacagucaa agacaggcaa caaaagacgc aggacaaaua aguggauuaa      720

acguauuaag aguaauaaau gaaccuacag cagcagcauu agcauauggc cuagauaaau      780

cagaagacaa aguaauagcg guauaugauu uaggcggagg aacauuugac auuucaauau      840

uagagauaca aaaaggugua uuugaaguua aaaguacaaa uggugacaca uuuuugggag      900

gagaagauuu cgaucaagca cuacuucgac auauaguuaa agaguuuaaa agagaaacag      960

ggguagaucu cacuaaagau aauauggcau ugcaaagggu aagggaagca gcugaaaaag     1020

caaagugcga gcuaagcuca ucuguacaaa cggauauuaa ucuaccauau uuaacaaugg     1080

acagcucagg uccaaaacau cucaauauga aauuaacaag agcucaauuc gaaggaauag     1140

uaacggacuu aauaagaaga acuauagcac caugucaaaa agcuaugcag gaugcggaag     1200

ugagcaagag ugacauagga gaaguuaucu ugguaggugg aaugacaaga augccaaaag     1260

uucaacagac aguacaagau cuauucggga gagcuccuag uaaagcuguu aauccagacg     1320

aagccguagc cauaggagca gcaauacaag gaggaguauu agcaggagau guaacugaug     1380

uacuacuauu agauguaaca ccguugagcc uuggaauaga aacuuuagga ggaguguuca     1440

cuaaauuaau caauagaaau acaacgauac cuacgaagaa aucacaagua uucaguacag     1500

cagccgaugg gcaaacacaa guagaaauaa aagucugcca aggagaaaga gagauggcag     1560

gagauaauaa auuguuaggg caauuuacau uaauagguau accuccagca ccgagaggag     1620

uaccucagau agaaguuaca uucgauauag augcaaaugg uauaguucau guaucagcaa     1680

aagacaaagg aacuggaaga gaacaacaaa uagugauaca aagcagugga ggacuaagua     1740

aagaugauau agaaaacaug guuaaaaacg cggaaaaaua ugcagaagaa gauagaagaa     1800

agaaagagag aguagaagca guuaacaugg cugaaggaau aauacaugac acugaaacaa     1860

aaauggaaga auuuaaagau cagcuaccag cagaugaaug uaauaaacua aaagaggaaa     1920

uaaguaaaau gagagaauug uuagcuagaa aagacaguga gacuggagaa aauauuagac     1980

aagcagcaag cucauuacaa caagcaagcc ucaaauuauu ugagauggca uauaagaaaa     2040

uggcaucaga aagggaagga uccggaucaa gcggaacggg agaacaaaaa gaagaucaaa     2100

aagaagaaaa acaauaggga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  4419
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt6)

<400>  4419
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagacaaag aagcaggcgg aagugauggg ccaagagaaa      120

cagcaccaac aucagcauac aguucaccag caagaagccu aggagacaca ggaauaaccc      180

cauuaagucc aucgcacauu guaaacgaca cagacuccaa cguaagcgaa caacaaaguu      240

uccuaguagu aguagcugua gauuuuggaa ccacaucauc aggauacgca uacucauuua      300

caaaagaacc ugaauguaua caugucauga gaagauggga aggcggagau ccuggaguaa      360

guaaucaaaa aacuccaaca acaauacuuc ucacaccaga acgaaaauuc cacucauuug      420

gauaugcagc cagagacuuu uaccacgauu uagauccaaa ugaagcaaaa caaugguuau      480

accuagaaaa auucaaaaug aaacuucaua ccacuggaga uuuaacaaug gacacagacc      540

uaacagcagc caauggaaaa aaaguaaaag cacuagagau auuugcauac gcacuacaau      600

acuuuaaaga acaagcacua aaagaauuaa gcgaccaagc agguuccgaa uuugaaaauu      660

cagacguaag auggguaaua acaguccccg caauauggaa acaacccgcc aagcaauuua      720

ugagacaggc agcauaccaa gcgggacuag ccuccccaga aaacucagaa caacuaauua      780

uagcacuuga accagaggca gcgucaauau auuguagaaa acuacgauua caucaaauga      840

uagaauuaag uucaaaagca gcaguaaaug gauacucagg aucagauaca gugggagcag      900

gauuuacaca agcuaaagaa cauauuagaa gaaacagaca aagcagaaca uuucuuguag      960

aaaacgucau aggagaaaua ugguccgaac uagaagaagg agauaaauau guaguaguug     1020

acagcggagg aggaacagua gaucuaacug uccaucaaau cagacuaccc gaagggcacu     1080

uaaaggaacu auacaaagca acgggaggcc cauacggcuc auuaggaguu gacuacgaau     1140

ucgaaaaauu auuauacaaa auauucggag aagauuuuau agaacaauuu aaaaucaaaa     1200

ggccugcagc auggguagau uuaaugauag cauuugaaag cagaaaaaga gccgcagcac     1260

ccgauagaac aaacccacua aauauaacac uaccguucuc auuuauagau uacuauaaaa     1320

aauuuagagg acauucggua gaacaugcac uaagaaaaag caacguugac uuugucaaau     1380

ggagcaguca aggaauguua cggaugagcc cagaugcaau gaaugcacua uucaaaccaa     1440

caauagauag uaucauagaa cauuuaagag auuuauuuca aaaaccagaa gucaguacag     1500

uaaaauuccu auucuuagua ggcggauucg cagaagcacc ccuauuacaa caagccguac     1560

aagcagcauu cggagaucaa uguagaauaa uaaucccaca agaugucgga cucacaauac     1620

ucaaaggagc aguucuauuc ggacucgacc cagcaguaau uaaaguaaga agaucaccac     1680

uuaccuaugg uguuggugua uuaaauagau auguagaagg aaaacacccu ccagaaaaau     1740

uauuaguaaa agauggaaca agauggugca cugacguauu ugauaaauuu auuucggcag     1800

accaaucagu agcucuaggu gaacuuguaa aacgauccua uacaccugca aaaccaucac     1860

aacuagucau aguaauaaau auauacuccu cagaacacga uaaugucuca uuuaucacug     1920

acccaggagu aaaaaaaugu ggcacauuaa gauuagauuu gacagguaca agugguacug     1980

caguacccgc acgaagagaa auccagacau uaaugcaauu uggcgacaca gaaaucaaag     2040

ccacagcaau agacauagcc acaucuaaau caguaaaagu aggaauagac uucuuaaauu     2100

auuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  4420
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt6)

<400>  4420
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuugcaguuc cagaaauggg acuacaagga cuauauauag      120

gcaguucacc agaacgaagu ccgguaccca guccaccggg aucaccaagg acacaagaaa      180

guugcggaau agcaccucua acaccuagcc aaucaccuaa accugaagug agagcaccac      240

aacaagcgag uuucucgguu guaguagcaa uagauuucgg aacaacauca agugguuaug      300

cauuuucauu ugcuucagau ccagaagcua uacauaugau gcgaaaaugg gaaggaggcg      360

auccuggcgu agcacaucag aaaaccccua cuugucuauu gcuaacacca gaaggagcau      420

uucauaguuu uggauauacc gcucgagauu acuaucauga cuuagaucca gaagaagcaa      480

gggauugguu auacuuugaa aaauuuaaaa ugaaaauaca uagugccacg gaucuaacau      540

uaaaaacaca auuagaagca guaaauggaa aaacaaugcc agcauuagaa guauuugcac      600

acgcauugag auucuuucgc gaacaugccu uacaagaacu acgcgaacaa uccccuuccu      660

uaccagaaaa ggauacugua cgauggguau uaacaguccc cgcuauaugg aaacaaccgg      720

cuaaacaauu uaugagagaa gcagcauauu uggcuggccu agucagccgg gaaaacgcug      780

aacaauuacu aauagcauua gaaccagaag cugcaagcgu auacuguaga aaacuaagac      840

uucaucaauu acuagaucua agcggaaggg caccuggagg agggcgauua ggagaaagaa      900

gaucuauaga uucaucauuu agacaagcua gagaacaauu aagaagauca cgucacucaa      960

gaacauuucu aguugaauca gguguaggcg aacuuugggc agaaaugcaa gcaggagaca     1020

gauauguagu ggcugacugc ggagggggua caguugaccu aacaguacau caauuagaac     1080

aaccacacgg aacacuaaaa gaauuauaua aggcuucagg aggaccauac ggggcaguag     1140

gaguugaucu agcuuuugaa caacuacuuu gucgaauauu cggugaagau uuuauagcaa     1200

cauuuaaaag gcaaagaccu gcugcauggg uagaucuaac uauagcauuc gaggcaagaa     1260

aacgaacagc aggaccacau agagcuggug cuuuaaacau uucauuacca uuuucauuca     1320

uagauuuuua cagaaaacaa agaggacaua auguagaaac agcauuaaga agaaguucag     1380

uaaauuuugu aaaauggucu agucaaggaa ugcuaagaau gucaugcgaa gcuaugaacg     1440

aacuauuuca acccacagua uccgguauaa uacaacauau agaagcacua uuagcuagac     1500

cugaaguaca aggaguaaaa uuauuauuuu uaguaggagg auucgcagaa ucagcugugu     1560

uacaacaugc ugugcaagca gcguugggcg cuagaggucu aagaguagua guuccucacg     1620

auguaggacu aacaauacua aaaggagcag uauuauucgg ccaagcgccu ggaguaguuc     1680

gaguaagaag aucuccauua acauauggug ugggaguauu aaauagauuc gugccaggua     1740

gacauccacc agagaagcua uuaguaagag auggcaggag gugguguacu gaugucuucg     1800

aaagguuugu ugcagccgaa caaagcguug cacuaggaga agaaguuaga agaucauacu     1860

guccagcacg gccaggacaa agaagagugc uaauuaacuu auauuguugc gcagcagaag     1920

augcaagauu uauuacagac ccagguguaa gaaagugugg agcccucagu uuagaacuug     1980

aaccagcuga uugcggccaa gauacagcag gcgcaccccc aggcagacga gaaauaagag     2040

cggcaaugca auuuggagau acagaaauaa aaguuacagc uguagaugua agcacaaaca     2100

gaaguguuag agcaucaaua gacuuucuaa guaacuaagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  4421
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt6)

<400>  4421
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuagagaaa ugacaauacu cggcucugca guauuaaccu      120

uacuauuagc aggauauuua gcacaacaau accuucccuu accaacacca aaaguaauag      180

guauagaucu cgguacaaca uauuguuccg ucggaguuuu cuuuccagga accggaaaag      240

uuaaaguuau accagacgaa aauggacaca uauccauacc aaguauggua aguuuuaccg      300

acaacgaugu auaugucggu uacgaaagcg uagaauuagc agauaguaau ccacaaaaca      360

caauauauga cgcaaaaaga uucauaggaa aaaucuucac cgcagaagaa cuggaagcag      420

aaauaggaag auauccauuc aaaguacuaa auaaaaaugg aaugguagaa uucucaguaa      480

cuuccaauga aacaauaaca guaucaccag aauaugucgg cucaagauua uuauuaaaau      540

uaaaagaaau ggcagaagca uacuuaggaa ugccaguagc aaacgcagua aucucaguac      600

cagccgaauu cgauuuaaaa caaagaaauu ccacuauaga agcagcaaau cuagcagguc      660

uuaaaauauu aagaguaaua aaugaaccca cagcagcagc aauggcauau ggacuacaca      720

aagcagaugu uuuucacgua cuagugauag auuuaggagg cggcacauua gacguaaguc      780

uacucaauaa acaaggcggu auguuucuaa caagagccau gaguggaaac aacaaauuag      840

gaggacaaga cuuuaaccaa agacuacuac aauauuuaua caaacaaauu uaccaaacau      900

auggauucgu cccaucaaga aaagaggaaa uccacagacu aaggcaagca guagagaugg      960

ucaaacuaaa cuuaacauua caucaaucag cacaacuauc agucuuauua acaguagaag     1020

agcaagauag aaaagaaccu cacuccagug acacagaacu cccuaaagau aaacuaucau     1080

cagcagauga ccaccgaguc aacaguggau ucggaagagg ccuaagugac aaaaaaagcg     1140

gagaaucaca aguauuauuu gaaacugaaa uuagcagaaa acuauuugau acauuaaaug     1200

aagaccuauu ucaaaaaaua cuaguaccaa uacaacaagu acucaaagaa ggacauuuag     1260

aaaaaacaga aauagacgaa guaguacuag uaggaggaag cacacgaauu ccuagaauaa     1320

gacaaguaau acaagaauuu uucggcaaag acccuaauac aucaguagac ccagaucuag     1380

ccgucguaac aggaguagca auacaggcag gaauagaugg aggaagcugg ccacuucaag     1440

ucagugccuu agaaauccca aacaaacauu uacaaaaaac caauuucaac uaaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4422
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt6)

<400>  4422
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagcaauag gaguacaccu aggauguaca ucagcaugug      120

uagccguaua uaaagauggu agagcaggag uuguggccaa ugaugccgga gauagaguaa      180

cuccugcagu aguugcauac agcgaaaaug aagagauagu uggacuagcu gcaaaacaaa      240

gcagaauaag aaauauaagu aauacaguaa ugaaagucaa acaaauauua ggaagaucaa      300

guucagaccc ucaagcucaa aaauacauug cugaaagcaa augucuagua auagagaaaa      360

auggaaaacu aagauaugaa auugauacgg gugaagaaac uaaauucgua aacccagaag      420

auguagcaag acuaauauuu aguaaaauga aagaaacagc ucauucagua uuaggaucag      480

acgcaaauga cguaguaaua acuguaccau ucgauuuugg agaaaaacaa aagaacgcuu      540

uaggagaagc ggcuagagca gcagguuuua auguauuaag acuaauacau gaaccauccg      600

cugcacuauu agcauacgga auaggacaag auaguccaac agguaaauca aauauccuag      660

uauucaaauu aggaggaaca ucauuaucgu uaucaguaau ggaaguaaau agugggauau      720

auagaguauu gagcacaaau acagaugaua auauaggcgg agcacauuuu acagaaacuc      780

uagcacaaua ucuagcaagu gaauuucaaa gaaguuuuaa acaugauguu cgaggaaaug      840

caagagcaau gaugaaauua acaaauucag cggaaguagc aaaacacuca uuaagcacgu      900

uagguagugc aaauuguuuc uuagauaguu uauaugaagg acaagauuuu gauuguaaug      960

uaucacgagc ccgauuugaa uuauuaugua gcccucuauu uaauaaaugu auagaagcaa     1020

uaaggggauu acucgaucaa aauggauuca cagcugauga uauaaauaaa guaguauuau     1080

guggagguuc aaguagaaua ccuaaauuac aacaacuaau aaaagacuua uuuccagcag     1140

uagaacugcu aaauaguaua ccgccagacg aaguaauacc aauaggagca gcaauugaag     1200

ccggaauacu aauuggaaaa gaaaaucuau uaguagaaga cagccuuaug auagaaugua     1260

gugcaagaga cauacucguc aaaggcguag augaauccgg agcaaguaga uucacuguau     1320

uauucccauc aggaacgcca cuaccagcaa gaagacaaca uacacuacaa gcaccaggaa     1380

gcauaucaag uguaugucua gaacuauaug aaucagacgg gaaaaauagc gcaaaagaag     1440

aaacaaaauu ugcacaagua guauuacaag auuuagacaa gaaagaaaau ggauuaagag     1500

auauauuagc aguauuaacu augaaacgag acggaagucu acauguaaca uguacagauc     1560

aagagacagg aaaaugugaa gcgauaucaa uagaaauugc uagcuaagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  4423
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt6)

<400>  4423
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaguaguag gacuugaugu aggaucacaa ucauguuaua      120

uagcaguagc acgagcagga gguauagaaa caauagcaaa ugaauucagc gauagaugua      180

caccuucagu cauaucuuuc ggaucaaaga aucgaaccau uggcguagcc gcaaaaaacc      240

aacaaaucac gcacgcuaac aauacaguau caaacuuuaa aagauuucac ggucgagcgu      300

uuaaugaccc cuucauucaa aaagaaaaag aaaacuuaag cuaugaccuu guaccacuua      360

aaaauggagg aguaggcauu aaaguaaugu acaugggaga agaacaccua uuuaguguag      420

aacaaaucac cgcgaugcua cuaacaaaac uaaaagaaac agcagagaau agccuaaaaa      480

aaccaguuac ugacugcgua auaaguguac caucuuucuu uaccgacgca gaaagacggu      540

ccguucuaga ugcagcccaa auaguaggau uaaacugucu cagacuaaug aaugauauga      600

cugcaguggc ucuaaauuau ggaauauaua aacaagacuu gccaucacua gaugaaaaac      660

caagaaucgu agucuucguc gauaugggcc auagcgcauu ucaaguuuca gcaugugcuu      720

ucaacaaagg aaaacugaaa guucuaggaa cggcauucga uccauuucua gggggaaaaa      780

auuuugacga aaaauuagua gaacacuuuu gcgccgaauu caaaacaaaa uacaaacuag      840

acgcaaaaag uaaaauaaga gcauuauuga gauuauacca agaaugcgaa aaacuaaaaa      900

aauuaaugag cuccaacuca acagacuugc cauuaaacau agaaugcuuc augaaugaua      960

aagacguauc cgguaaaaug aauagauccc aguucgagga acuaugugcc gaacuacuuc     1020

aaaaaauaga aguaccauua uacucacuau uagaacaaac ucaccuaaaa gucgaagacg     1080

uaagugcagu agaaauugua gguggagcaa caagaauacc ggcuguaaaa gaaagaauag     1140

caaaauucuu uggaaaagau auaucaacaa cauuaaacgc cgaugaagcc guagcuagag     1200

ggugcgcacu ucaaugcgcc auauuaucac cagcguuuaa agucagagaa uucaguguua     1260

ccgaugcagu accauuccca auaaguuuaa uauggaacca ugacucagaa gacaccgaag     1320

gaguucauga aguauuuagc cgaaaccacg ccgcaccauu uaguaaagua uuaacauuuc     1380

uaagacgugg uccauuugag cuugaagcau uuuauucuga uccacaagga guaccauacc     1440

cagaagcaaa aauaggcaga uuugucguac aaaacguauc ggcacaaaaa gauggagaaa     1500

aaucacgagu caaaguaaag gugagaguaa acacacaugg aauauucaca auaaguacag     1560

ccagcauggu ggaaaaaguu ccaacagaag aaaacgaaau gagcagcgaa gcagauaugg     1620

aaugucuaaa ccaaagaccg ccagaaaacc cagacacaga uaagaauguc caacaagaca     1680

acucugaagc aggcacucaa ccacaaguuc aaacagaugc acaacaaacu ucacaaucac     1740

caccgucucc agaauuaacc agugaagaaa acaaaauacc cgacgcagau aaagcaaacg     1800

aaaaaaaagu agaccaacca ccagaagcaa agaaaccaaa aauuaaaguc gugaacguag     1860

aauuaccaau agaagcaaau cuaguauggc aauuaggcaa agaccuauua aauauguaua     1920

ucgagaccga agguaaaaug auaaugcaag acaaauuaga gaaagaacga aaugaugcaa     1980

aaaaugcagu agaagaauau guauaugaau uuagagauaa acuaugugga ccguacgaaa     2040

aauuuauaug ugaacaagac caucaaaauu uucuacgacu ucuaacugag acagaagacu     2100

ggcuauacga agaaggagaa gaucaagcaa aacaagcgua uguagacaaa cuagaagaau     2160

uaaugaagau agguacacca guaaaaguac gauuccaaga agcagaagag agaccaaaaa     2220

uguuugaaga acugggucaa agauuacaac acuaugcaaa aaucgccgca gacuuucgaa     2280

acaaagacga aaaguauaau cauauagaug aaucagaaau gaaaaaaguc gaaaaaagug     2340

ucaacgaagu gauggagugg augaauaacg uuaugaaugc acaagccaaa aaaagccuag     2400

aucaagaucc uguaguaaga gcacaagaga ucaaaaccaa aauaaaagaa cuaaauaaca     2460

ccugcgagcc agugguuacc cagccaaaac caaaaauaga aagucccaaa uuagagagaa     2520

cccccaaugg accaaauaua gauaaaaaag aagaagaccu agaggauaaa aauaacuucg     2580

gagccgaacc accacaccaa aauggggaau guuaccccaa cgaaaaaaau aguguaaaca     2640

uggauuuaga cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  4424
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt6)

<400>  4424
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcugauaaag ucagacgaca acggccaaga agaaggguau      120

gcugggcacu gguagcaguu cugcuagccg auuuauuagc guuaucagau acccuagcug      180

uaaugagcgu agacuuaggc agugaaagua ugaaaguggc aauaguaaaa ccaggaguac      240

ccauggagau uguuuuaaau aaagaaucaa gaagaaagac gccaguaaua guaacgcuaa      300

aagagaacga aagauucuuu ggagacucag cagcaaguau ggcaauuaaa aacccaaaag      360

caacccugag auacuuucaa caucuguugg gcaaacaagc agacaaccca cauguagcgc      420

uauaccaagc gagguuuccu gaacacgaac uaacauucga cccacaaaga caaacaguac      480

acuuccaaau aucuucacaa cuccaauuuu caccugagga aguacuugga auggucuuaa      540

acuacagucg aaguuuggcg gaagauuuug ccgaacaacc uauaaaagau gcaguaauaa      600

caguaccugu auucuuuaau caagccgaga ggagagcugu auuacaagcu gcaagaaugg      660

cuggacuuaa aguacuacaa cucauaaaug acaauacagc uacugcacua ucauauggug      720

uuuuuagaag aaaagacaua aacacaacug cacaaaauau cauguuuuac gauaugggaa      780

gcggaagcac agucugcacu auagucaccu aucagauggu gaaaacaaaa gaagcaggaa      840

ugcagccuca auuacaaaua agaggaguag guuuugacag aacgcugggu ggauuagaaa      900

uggaacugag auuaagagaa cgauuggcag gacuauucaa ugagcaacga aagggucaga      960

gagcuaaaga cguuagagaa aauccucgcg caauggcuaa acuuuuacgc gaagcaaaua     1020

gauuaaagac aguacuuagu gcaaacgcag accauauggc ucaaauagaa ggacuaaugg     1080

augacguaga cuuuaaagca aaaguaacac gaguagaguu cgaagaacua ugugcagauc     1140

ucuuugaaag aguaccuggu ccaguacaac aagcucuaca aagugcugaa augucuuuag     1200

acgaaauuga acaaguaaua uuggucggcg gagcaacacg aguuccuaga guacaagaag     1260

uauugcuuaa ggcaguagga aaagaagaac uagggaaaaa uauaaacgcu gacgaagcag     1320

cagcaauggg agccguuuac caagcggcag cacuaagcaa ggcuuuuaaa guuaaaccau     1380

uuguaguaag agaugcaguu guauauccaa uuuuaguaga auuuacucga gaaguagaag     1440

aagaaccagg gauacacuca cuaaaacaca acaaaagagu acucuuuagc aggaugggac     1500

cguauccaca acguaaaguc auaacauuua acagauauuc ucaugauuuu aauuuccaua     1560

uaaacuacgg agacuuaggc uuuuuagguc cagaagaucu aaggguauuu gguucacaaa     1620

aucucacaac gguuaaacua aaagggguag gagauaguuu caagaaauac ccagacuaug     1680

aaucuaaagg aauaaaagca cauuuuaauc uagaugaaag ugggguauug agucuagacc     1740

gagucgagag cguauucgaa acucugguug aagauagugc cgaagaggaa ucaaccuuga     1800

cuaaacuagg uaauacgaua agcagcuuau ucggaggugg cacaacacca gaugcaaaag     1860

aaaauggaac agacacagua caggaagaag aagaaagccc ggcagagggc ucaaaagaug     1920

aaccugggga acaaguagag uuaaaagaag aagcagaagc accaguggaa gacgguucgc     1980

aaccaccucc cccagagcca aaaggugaug caacaccaga aggcgaaaaa gcaacagaaa     2040

aagaaaaugg ggauaaauca gaagcacaaa agccaaguga aaaagcagaa gcuggaccag     2100

aaggaguugc uccugcacca gaaggagaaa agaaacaaaa acccgcacgc aaaagaagaa     2160

ugguagagga aauagguguc gagcuaguag uauuagaucu accagaucuc ccagaagaca     2220

aauuggcaca aaguguacaa aaacugcagg acuuaaccuu aagagacuua gaaaaacaag     2280

aaagggaaaa agcugcaaau ucuuuggaag cauucauauu cgaaacacag gacaaauuau     2340

aucaacccga auaucaggaa guauccacag aagaacaaag agaagaaaua ucaggaaaac     2400

ucucagcagc aucaacgugg uuggaagaug aaggaguagg ugcaacaaca guaauguuaa     2460

aagaaaaauu agcagaacua aggaaacugu gccaaggauu auuuuucaga gucgaagaaa     2520

gaaagaaaug gccagaacgg uuaucugcau uagauaauuu acuaaaccac ucuaguaugu     2580

uucuaaaagg ggccagauua auaccagaaa uggaucaaau uuuuacugaa guagaaauga     2640

caacacuaga aaaaguaauc aacgaaacau gggcauggaa aaaugcaacu uuagcagaac     2700

aagcaaaauu accggcaaca gaaaaaccag ucuuacuauc aaaagacaua gaagcgaaaa     2760

ugauggcauu agacagagaa guccaauacc uacuaaacaa agcaaaguuc acaaaaccca     2820

gaccgcggcc aaaagauaaa aacggaaccc gagccgagcc accacuaaau gcaagcgcaa     2880

gugaucaagg ggagaaggua auaccgccug caggacaaac agaagacgca gaaccaaucu     2940

ccgaaccaga aaaaguagaa acaggaucgg aaccuggaga uacagaaccc cuagaauuag     3000

gaggaccugg agcugagcca gaacaaaaag aacaaaguac aggacaaaaa cgaccucuua     3060

aaaaugacga acuauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4425
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt6)

<400>  4425
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaagaaa cccaaacaca agaccaaccc auggaagaag      120

aggaaguaga aacauucgcu uuccaagcag aaauugcaca auuaaugagu cuaauuauaa      180

acacauucua cucaaacaaa gaaauauuuu uacgcgaacu aauaagcaac ucaagcgaug      240

cauuagauaa aauuagauau gaaucguuaa cagauccaag caaauuagac ucaggaaaag      300

aauuacacau aaaucuuauc ccaaacaaac aagauagaac acuuaccaua gucgacaccg      360

gaauaggaau gacaaaagcu gaccuaauaa acaauuuagg uacaauagca aaaucgggua      420

ccaaagcauu cauggaagca cuacaagcag gugccgacau cucgaugaua ggacaauuug      480

gaguaggauu cuacagcgca uaccuaguag cagagaaagu aacaguuaua acaaagcaca      540

acgacgacga acaauacgcc ugggaaucaa gugcaggagg aucauucaca guaagaacag      600

acacagguga accaaugggc agagguacga aaguaauacu ucaucuuaaa gaagaccaaa      660

cagaauaccu agaggaaaga agaaucaaag aaauaguaaa aaaacacuca caauucauag      720

gauauccaau aacacucuuu guagagaaag aaagagacaa agaagucagu gacgaugaag      780

cagaggaaaa agaagauaaa gaagaagaaa aagaaaaaga agaaaaagaa agugaagaca      840

aaccagaaau agaagacgua ggaucggaug aggaggaaga aaaaaaagau ggagacaaaa      900

aaaaaaagaa aaaaauaaaa gaaaaauaca uagaucaaga agaacugaac aaaaccaaac      960

caauauggac aaggaacccc gacgacauca caaacgaaga auacggagaa uuuuacaaau     1020

cacuuacaaa ugacugggaa gaccaccucg ccgucaaaca cuuuagcgua gaaggucaau     1080

uagaauucag agcccuacug uuuguaccua gaagagcacc auucgauuug uuugagaaua     1140

gaaaaaaaaa aaauaauauc aaacuauacg uaagaagagu auuuauaaug gacaauugcg     1200

aagaauuaau accagaauau cuaaauuuua ucaggggagu agucgacagc gaagauuuac     1260

cauuaaacau aucgcgagag auguuacaac aaucaaaaau ucugaaagua auaagaaaaa     1320

aucuagucaa aaaaugucua gaacuauuca cagaacuagc agaagacaaa gaaaacuaca     1380

aaaaauucua ugaacaauuc ucaaaaaaua uaaaauuggg cauacacgaa gacucucaga     1440

auagaaaaaa acuaucagaa uuacuaagau auuauacguc agcuagugga gacgagaugg     1500

uaucccuaaa agacuacugc acaaggauga aagaaaauca aaaacauaua uacuacauaa     1560

cuggagaaac caaggaccaa gucgcaaacu cagcauucgu agaaagauua cgaaagcaug     1620

gacuggaagu aauauacaug auagaaccca uagaugaaua uugcguacaa caauuaaaag     1680

aauucgaagg aaaaacuuua guaagcguaa cgaaagaagg acuagaauua cccgaagaug     1740

aagaagagaa aaaaaaacaa gaagagaaaa aaaccaaauu cgaaaacuua uguaaaauaa     1800

ugaaagacau auuagaaaaa aaaguagaaa aaguuguagu aucaaacaga cuaguaacaa     1860

gcccauguug cauaguaaca aguaccuacg gguggacggc aaacauggaa agaauaauga     1920

aagcccaagc uuuacgagac aauaguacga ugggauacau ggcagccaaa aagcauuuag     1980

aaauaaaccc agaccacagc auaaucgaaa cacuuagaca aaaagccgaa gcugauaaaa     2040

acgacaaauc cgugaaagac cucgucaucu uacuuuauga aacagcauua uuaaguagug     2100

gauucucccu agaagacccg caaacacacg cuaaucgaau auaccgaaug auuaagcucg     2160

gauuaggaau agacgaagau gacccaacag cggaugauac aagcgcagca guaacugaag     2220

agaugccacc auuagaagga gaugaugaua cgucaaggau ggaagaaguc gacuaaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  4426
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt6)

<400>  4426
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucaagca aacuagacag cggaaaagga cuacacauaa      120

acuuaguacc aaacaaacaa aaccaaacac uaacaauagu agacacaaga auaggaauga      180

caaaaacaga cuuaauaaac aaccuaggaa caguaacaaa aucaggaaca aaagcauuca      240

uggaagcacu acaagcagac gcagacauau caaugauagg acacuucgga guaggauucu      300

acucagcaua ccuaguagca aaaaaaguaa caguaauauc aaaacacaac aacgacgaac      360

aauacacaug ggaaucauca gcaggaggau cauucacagu aagaacagac gaauaaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  4427
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt6)

<400>  4427
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaagaag ugcaucaugg cgaagaggag guagaaacau      120

ucgcuuuuca agcugaaaua gcucagcuaa ugagccuaau aauaaacacu uuuuacagca      180

acaaagaaau auuucuccgc gaguuaauau caaacgcuuc agaugcacuu gauaaaauaa      240

gauacgagag ccuaacagac ccuaguaaac uagauagcgg uaaagaacua aaaauagaca      300

uaauacccaa cccgcaagaa agaacacuua cacuugucga uacuggaaua ggaaugacaa      360

aagcagaucu aauaaauaac uuaggaacaa uagcaaaauc agggacgaaa gcguuuaugg      420

aagcauuaca agcaggagca gauauuagua ugauaggaca auuuggagua ggauucuaca      480

gugcuuaucu uguagcagaa aaaguaguag uaauaacaaa acacaaugac gacgaacaau      540

augcuuggga aucuucagcc ggagggucau ucacgguuag agcagaccac ggagaaccaa      600

uaggaagagg cacuaaggua auacuacauu uaaaggaaga ucagacagaa uaccuugaag      660

aacgaagagu aaaagaagua guaaaaaaac auucacaauu uauaggauac cccauaacau      720

uauaccugga aaaagaaaga gaaaaagaaa uaucugacga cgaagccgaa gaagaaaaag      780

gagaaaaaga agaagaagac aaagaugaug aagaaaaacc gaaaaucgaa gacguaggau      840

cagacgaaga agacgacuca ggaaaagaca aaaaaaaaaa aacaaaaaaa auaaaagaaa      900

aauacauaga ucaagaagaa uugaacaaaa caaaaccaau auggacaaga aauccagaug      960

auauaacaca agaagaauau ggagaauucu acaaaagucu uacaaaugac ugggaagacc     1020

aucuagcagu caaacauuuu ucaguagaag gacaacuaga auucagagcg uuauuauuua     1080

uaccaagaag agcgccauuc gaccuauuug aaaacaaaaa aaaaaaaaac aauauaaaac     1140

uauacguaag aagagucuuc auaauggacu cgugcgauga auuaauacca gaauacuuaa     1200

auuucauaag aggaguaguc gauuccgaag acuuaccacu aaauauaucu cgagaaaugu     1260

uacaacaauc caaaauacua aaagugauaa gaaaaaauau cguaaaaaaa ugucuugaac     1320

uauuuucgga acuugcggaa gacaaggaaa auuauaaaaa auuuuaugaa gcguucagua     1380

aaaacuuaaa gcuaggcaua caugaagacu ccacaaauag aagaagacua agcgaacuau     1440

uaagauacca uacaucacaa ucaggagacg aaaugacauc ucuaagugaa uaugugagca     1500

ggaugaaaga aacccaaaaa ucaauauacu acauaacagg agaaucgaaa gaacagguag     1560

caaauucagc auucgucgaa cguguacgca aaagaggauu ugaaguagua uacaugacug     1620

agccaauaga cgaauauugu guacaacaac uaaaagaauu cgacggaaaa agucuaguca     1680

guguaacaaa agaaggacua gaacuaccag aagaugaaga agaaaaaaaa aaaauggaag     1740

aaagcaaagc aaaguucgaa aauuuaugca aauuaaugaa agaaauacua gauaaaaaag     1800

ucgaaaaagu uacaauuuca aauagacuag ucucaucacc augcugcaua gucacaagca     1860

cauacggaug gaccgccaau auggaaagaa uaaugaaggc acaagcauua agagauaaca     1920

gcacgauggg auacaugaug gcaaaaaaac aucuugaaau aaauccagac cacccaauag     1980

ucgaaacacu aagacagaaa gcagaagcag auaaaaacga caaagcugua aaagaccucg     2040

ugguccugcu cuucgaaaca gcauuacuga guucaggauu cucgcuggaa gacccacaga     2100

cucauucaaa uagaauuuac agaaugauaa aacuaggauu aggaaucgau gaagacgaag     2160

uggcagcaga agaaccaaac gccgcggucc cagacgaaau accuccauua gaaggagacg     2220

aggaugcaag ccgaauggaa gaaguagauu aaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  4428
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt6)

<400>  4428
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgagcuuuau ggguacuagg cuuauguugc guauuacuua      120

cauucggauc aguacgugca gacgaugaag uagauguaga ugguacagua gaagaagauu      180

uaggcaaauc aagagaagga aguaggacag acgaugaggu aguacaaaga gaagaagaag      240

caauucaacu agacggacuu aacgcaucuc aaauaagaga auuacgagaa aaaucagaaa      300

aauuugcauu ccaggcagaa guaaauagaa ugaugaaacu aaucauaaau agucucuaua      360

aaaacaaaga aauauucuua cgagaacuaa uaucaaaugc aagugaugcu uuagacaaaa      420

uacgacuuau cagucuaaca gaugaaaaug cacucagugg caaugaagaa cuaacaguua      480

aaauaaaaug cgauaaagag aaaaauuuac uacauguuac agacaccggu guaggaauga      540

caagagaaga auuaguuaaa aauuuaggaa caauagcaaa aaguggaaca agugaauuuc      600

uaaauaaaau gacugaagcu caggaagaug gacaaagcac uucagaacua auuggacaau      660

ucggaguagg auucuacuca gcauuccuug uagcugauaa aguaaucgua acuagcaaac      720

acaauaacga cacacaacau auaugggaau cagauucaaa cgaauuuagc guaauugcag      780

auccaagagg aaauacacua ggaagaggga ccacaauaac auuaguacua aaagaggaag      840

caagcgacua cuuagaacuc gauacgauua aaaauuuagu aaagaaauac ucacaguuua      900

uaaauuuccc aauauacguc uggaguagua aaacagaaac aguagaagaa ccaauggagg      960

aagaagaagc agccaaagaa gaaaaagaag aaucggacga cgaagcugcu gucgaagaag     1020

aagaagaaga aaagaaacca aaaacaaaga aaguagagaa aacuguuugg gauugggaau     1080

uaaugaacga uaucaaacca auauggcaaa gacccucaaa agaagucgaa gaagacgaau     1140

auaaagccuu uuacaaguca uuuuccaaag aaucggauga cccaauggca uauauucacu     1200

uuacagcaga gggagaaguc acauuuaaau cuauacuuuu ugucccaaca agugcaccga     1260

gaggauuauu ugaugaauac gguucaaaga aaucagacua uauaaaauua uauguaagaa     1320

gaguguucau aacagacgac uuucacgaua ugaugccgaa auacuuaaac uuuguuaaag     1380

gagucguuga cagcgaugac cuaccacuca acguaaguag agaaacacua caacaacaua     1440

aacuauugaa aguuauaaga aagaaacucg uaagaaaaac uuuagacaug auuaagaaaa     1500

uagcagacga caaauauaac gauacauuuu ggaaagaguu cgguacaaau auaaaacuag     1560

gaguaauaga agaccacagu aauagaaccc gauuagccaa auuacucagg uuccaaucau     1620

cgcaucaccc aacagacauc acgagcuuag aucaauaugu agaaagaaug aaagaaaaac     1680

aagauaaaau auacuuuaug gcgggaucau caagaaaaga agccgaaucu ucuccauucg     1740

uugaacgacu auuaaagaaa ggauaugaag uaauauaccu aacagaaccu guagaugaau     1800

auuguauaca agcacuacca gaauuugaug gcaaacgcuu ccaaaaugua gcaaaagaag     1860

gcguuaaauu ugaugaaagc gaaaagacaa aagaaaguag agaagcgguu gaaaaagagu     1920

ucgaaccauu auuaaauugg augaaagaca aagcacuaaa agauaaaaua gaaaaagcug     1980

uaguaucuca aagauuaacc gaauccccgu gcgcacucgu agccagucaa uauggcuggu     2040

cagguaacau ggaaagaaua augaaagcuc aagcauauca aacaggaaaa gauauaagua     2100

cgaacuauua cgcaucucaa aagaaaacau ucgaaauaaa uccaagacac ccacugauaa     2160

gagauauguu aaggcgaaua aaagaagaug aagacgacaa aacaguucua gacuuagcug     2220

ucguacuauu cgaaacagca acauuaagaa gcggauacuu acuaccagac acaaaagcau     2280

auggagauag gauagaacgg auguuacgac uaagucucaa cauagaucca gaugccaaag     2340

uugaagaaga accagaagag gaaccagaag agaccgcaga agacacaaca gaagacacag     2400

aacaggacga agacgaagaa auggacguag gaacugacga agaagaagaa acagcaaaag     2460

aaucuacagc agaaaaagac gagcuguaag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  4429
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt6)

<400>  4429
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacgagaau uaagagcucu uuuacuaugg gguagacgac      120

ugagaccauu auuaagggcg ccagcccucg cagcaguacc aggaggaaaa ccaauacucu      180

gcccaagaag aacaaccgca caauuaggcc caagaagaaa uccagcaugg ucauuacaag      240

cuggaagacu auuuuccacc caaacagcag aagauaaaga agaacccuua cauucaauaa      300

uaucaagcac agaaucaguc caaggaucaa caucaaaaca ugaauuucaa gcagaaacaa      360

agaaacuauu agauauuguu gcuagaagcc uuuauucuga aaaagaagua uuuauaagag      420

aacuaauuag uaacgcuagc gacgccuuag aaaagcuaag acacaaguua guaagugaug      480

gacaagcauu accagaaaug gaaauacacc ugcaaaccaa ugcagaaaaa ggaacaauaa      540

ccauacaaga uaccggcaua ggaaugacac aagaagaauu aguaaguaac cuuggaacaa      600

uagcuagaag cggaucaaaa gcauuccucg acgcacuaca aaaccaagca gaagcaucau      660

ccaaaauaau uggacaauuu ggcguaggau ucuauagugc cuuuauggua gcagaucgug      720

ucgaagucua uucacgauca gcagcaccag gaucacuagg guaucaaugg uuaucagacg      780

gauccggugu auucgaaauu gccgaagccu cgggcguaag aacggguacu aaaauaauaa      840

uacauuuaaa aucagauugc aaagaauucu cuucagaagc acgaguccga gauguaguaa      900

cgaaauauuc aaacuuuguu aguuuucccu uauauuuaaa uggucguaga augaauaccu      960

uacaagcaau auggaugaug gauccaaaag auguuagaga auggcaacau gaagaauuuu     1020

auagauaugu ugcucaagcu caugacaaac cccgauauac uuuacacuac aaaacagacg     1080

caccauuaaa uaucaggagu auauuuuaug ugccagauau gaaacccucg auguuugaug     1140

ucaguagaga auuaggaagc aguguggcuc uauauucuag aaaaguacuc auacaaacca     1200

aagcaacgga uauauuacca aaauggcuca gauuuauaag aggaguuguu gauucagaag     1260

acauacccuu aaaucuuagu agagaacuac uucaagaauc agcauuaaua agaaaauuaa     1320

gagacguccu ucaacaaaga uuaauuaaau ucuuuauaga ccaaucaaaa aaagaugcag     1380

aaaaauaugc aaaauucuuc gaagacuaug gauuauuuau gagagaagga auaguaacag     1440

caacagaaca agaaguaaaa gaggauauag caaaauuauu acgguacgaa ucaucagcau     1500

uaccaucagg acaacuuaca ucauuauccg aauacgccag ucgaaugaga gcaggcacaa     1560

gaaacauaua uuaccuaugu gcaccaaaca gacaucuagc agagcacuca ccuuauuacg     1620

aagcaaugaa aaaaaaagau acagaaguuc uauuuugcuu ugaacaauuu gacgagcuua     1680

ccuuacucca ucuaagagaa uuugacaaaa aaaaauuaau aaguguugaa acagacauag     1740

uaguugauca uuauaaagaa gaaaaauuug aagaucgaag cccagcagca gaaugccuau     1800

cagaaaaaga aaccgaagaa uuaauggccu ggaugcguaa uguucuagga agcagaguua     1860

caaacguaaa aguaacgcua agauuagaua cucauccagc caugguaacu gugcuagaaa     1920

ugggcgcagc caggcacuuc cuaagaaugc aacaauuagc aaaaacacaa gaagaaagag     1980

cacaauuacu ucaaccaaca cuugagauaa aucccagaca ugcauuaauc aaaaaacuaa     2040

accaacuucg ugcaagcgaa ccaggauuag cacaacuuuu aguugaucaa auauaugaaa     2100

acgcaaugau agcagcugga cucgucgaug auccaagagc aaugguggga cgccuuaaug     2160

aauuauuggu aaaagcauug gaacgacauu aaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  4430
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt6)

<400>  4430
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaauau caucacuacc aacacaacua uucaaaugcu      120

gcuucugcga cuuccuaaaa guaaaaaugc acacaauguc aucaucacac cuauucuacc      180

uagcacuaug ccuacuaaca uucacaucau cagcaacagc aggaccagaa acacuaugcg      240

gcgcagaacu aguagacgca uuacaauucg uaugcggaga cagaggauuc uacuucaaca      300

aaccaacagg auacggauca ucaucaagaa gagcaccaca aacaggcaua guagacgaau      360

gcugcuuccg aucaugcgac cuaagaagac uagaaaugua cugcgcacca cuaaaaccag      420

caaaaucagc aagaucagua agagcacaaa gacacacaga caugcccaaa acacaaaaag      480

aaguacaccu aaaaaacgca uccagaggau cagcaggaaa caaaaacuac agaauguaag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  4431
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt6)

<400>  4431
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaauaccaa ugggaaaauc aaugcuagua cuauuaacau      120

uucuagcauu ugcaagcugu ugcauugcag cauacagacc aucagaaaca cuauguggag      180

gagaauuagu agauacauua caauuuguau guggagauag aggauucuau uucucaagac      240

cagcaucaag aguuagcaga agaaguagag gaauaguaga agaaugcugu uucagaagcu      300

gugauuuagc auuacuagaa acauauugcg caacaccagc aaaaagugaa agagauguau      360

caacaccacc aacuguauua ccagauaacu uuccaagaua cccaguagga aaauucuuuc      420

aauacgauac auggaaacaa agcacacaaa gacuaagaag aggacuacca gcauuauuaa      480

gagcaagaag aggacacguu cuagcaaaag aacuagaagc auuuagagaa gcaaaaagac      540

auagaccacu aauagcauua ccaacacaag auccagcaca cggaggagca ccaccagaaa      600

uggcaucaaa cagaaaauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  4432
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt6)

<400>  4432
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aauuccuucu caacaucagc cuucggacca guagccuucu      120

cacuaggacu acuacuagua cuacccgcag cauucccagc accaguccca ccaggagaag      180

acucaaaaga cguagcagca ccacacagac aaccauuaac aucaucagaa cgaauagaca      240

aacaaauaag auacauauua gacggaauau cagcacuaag aaaagaaaca ugcaacaaau      300

caaacaugug cgaaucauca aaagaagccc uagcagaaaa caaccuuaau cuaccaaaaa      360

uggcagaaaa agacggaugc uuccaaucag gauucaacga agaaacaugc cuaguaaaaa      420

uaauaacagg acuacuagaa uucgaaguau accucgaaua ccuacaaaac agauucgaau      480

ccucagaaga acaagcccga gcaguccaaa ugucaacaaa aguacuaaua caauucuuac      540

aaaaaaaagc aaaaaaucua gacgcaauaa caacaccaga cccaacaaca aacgccuccu      600

uacuaacaaa acuacaagca caaaaccaau gguuacaaga caugacaaca caccucauac      660

uaagaucauu caaagaauuc cuacaauccu cacuaagagc acuuagacaa auguaaggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  4433
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt6)

<400>  4433
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuacugu gguuaagagg uuuccuauua gcaagcugcu      120

ggauaauagu aagaagcagu ccaacaccag ggagcgaagg acacagugcg gcaccagacu      180

gcccaucaug ugcgcuagca gcauuaccaa aagacguucc aaauagucaa ccagaaaugg      240

uugaagcagu aaaaaaacau auauuaaaua ugcuacaucu aaaaaaaaga ccagauguaa      300

cacaaccagu accgaaagca gcauuauuaa augcaauacg aaaauuacau gucggaaaag      360

uaggagaaaa cggauaugua gaaauagaag acgacauugg aagaagagca gaaaugaacg      420

aauuaaugga acaaacaagu gaaauuauaa cguuugcaga aucaggaaca gccagaaaaa      480

cacuacacuu ugaaauauca aaagaaggcu cagaccuauc aguuguagaa agagcggaag      540

uaugguuauu ucuaaaagua ccuaaagcaa acagaacaag aacaaaagua acaauuagac      600

uauuucaaca acaaaaacac ccacaaggaa gucuagauac aggagaagaa gcagaagaag      660

uaggauuaaa aggagaaagg agugaauuac uauuaaguga aaaaguagua gacgcaagaa      720

aaucaacaug gcacguauuu ccaguaucau caagcauaca acgacuacua gaccaaggaa      780

aauccucauu agauguaaga aucgcaugcg aacaauguca agaaaguggu gcaucauuag      840

uacuauuagg aaaaaaaaaa aaaaaagaag aagaaggaga aggaaaaaaa aaaggaggag      900

gagaaggagg ugcaggagca gacgaagaaa aagaacaaag ccauagacca uucuuaaugu      960

uacaagcaag acaaagugaa gaccauccuc auaggagaag aagaagagga cuugaaugcg     1020

acggaaaagu aaauauaugu uguaaaaaac aauucuuugu aagcuuuaaa gauauaggau     1080

ggaacgauug gauaauagcu ccaaguggau aucacgcaaa uuacugcgaa ggagaaugcc     1140

caucacacau agcgggaaca agcggaagcu cacuaucauu ccauagcaca guaauaaacc     1200

auuacagaau gagaggacau aguccauucg caaacuuaaa aucaugcugu gucccaacaa     1260

aacuaagacc aauguccaug uuauauuaug augacgguca aaauauaaua aaaaaagaua     1320

uacaaaacau gauaguagaa gaauguggcu guagcuaagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  4434
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt6)

<400>  4434
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gauggauuac ccgggagggc acuaggugca gcuugccuau      120

uacuacuagc agcaggaugg cuaggaccag aagcaugggg aagcccgaca ccaccuccua      180

caccagcagc accaccacca ccuccuccac caggaucacc aggaggaagu caagacacau      240

guacaucaug cggaggauuc cgaagaccag aagaacuagg aagaguagau ggagauuuuc      300

uagaagcagu uaaacgacau auacuaucua gacuacaaau gcgaggaaga ccaaauauaa      360

cacacgcagu uccaaaagca gcaaugguaa cagcacuuag aaaauuacau gcagguaaag      420

uacgugaaga uggaagagua gaaauaccac aucuagacgg ucacgcuuca ccaggagcug      480

acggucaaga aagaguauca gaaaucauca gcuuugccga aacugaugga cuagcaucau      540

cacgaguuag auuauauuuu uuuauuagua augaaggaaa ucaaaauuua uucguugucc      600

aagcuucauu auggcuuuau uuaaaauuac uaccuuaugu auuagaaaaa ggaucaagaa      660

gaaaaguaag aguuaaaguc uauuuccaag aacaagguca uggagauaga uggaauaugg      720

uagaaaaaag aguagaccua aaaagaucag gauggcacac uuucccauua acagaagcaa      780

uacaagcauu auucgaaaga ggagaaagaa gacuaaauuu agacguucaa ugugacucau      840

gucaagaauu agcaguagua ccaguuuuug ucgauccagg agaagaaagu cauagaccuu      900

uuguaguagu acaagcgaga uuaggagauu caagacacag aauaaggaaa agaggauuag      960

aaugugacgg gagaacaaac uuauguugua gacaacaauu uuuuauagau uuucgacuaa     1020

uaggauggaa ugauuggaua auagcaccua caggauauua uggaaauuau ugugaaggaa     1080

guuguccagc auauuuagca ggaguaccag gaucagcaag caguuuucau acagcaguag     1140

uuaaucaaua uagaaugaga ggacuaaauc cuggaacggu aaauucgugu ugcauuccua     1200

caaaacuauc aacaaugagc auguuauacu ucgaugacga auauaauaua guuaaaagag     1260

acguaccaaa caugauugua gaagaaugug gaugugcuug aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  4435
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt6)

<400>  4435
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucucagag uacuacuacu aacugcacua acuuuaugcc      120

acggcuucaa cuuagauacc gaaaacgcca ugacuuuuca agaaaaugca agagguuucg      180

gacaaucugu aguacaacua caaggcucaa ggguaguugu aggcgccccu caagaaaucg      240

uagccgcuaa ucagcgaggu ucucuuuauc aaugugauua uucaacugga uccugugaac      300

ccauccgauu acaaguaccu guagaagcug uaaauauguc acuuggacua agucucgcug      360

caacaacauc acccccgcaa cuacucgcau guggcccaac cguacaucag acauguucug      420

aaaacacaua cguaaaagga uuauguuucc uauuuggcag uaacuuacga caacaaccac      480

aaaaauuccc agaagccuua agaggauguc cucaagaaga uagcgauauu gcauuccuca      540

uagauggauc ugguuccauu auaccucaug auuuccggcg aaugaaagaa uuuguuucaa      600

cagucaugga acaacuaaag aaaucaaaaa cauuauuuuc cuuaaugcaa uauagugaag      660

aguuccgaau acauuuuacc uucaaagaau uucaaaauaa cccaaacccg cgaagucucg      720

uaaaacccau uacccaacuu cuagguagaa cucacacagc aacagguauu agaaaaguug      780

uucgagaguu auuuaauauu acaaacggag cacguaaaaa cgcuuucaaa auccuaguug      840

uaauaacaga cggagaaaaa uuuggugacc cacuagguua ugaagauguu aucccagagg      900

cugacagaga aggagucauu agauauguca uaggaguagg agaugcauuc cgcagugaga      960

aaaguagaca ggaacuuaac acgauagccu cuaaaccccc aagggaucac gucuuccaag     1020

uaaacaacuu ugaggcuuua aaaaccauac aaaaccaauu gcgugagaaa auuuuugcua     1080

uagaagggac acaaacugga uccucaucuu cauuugaaca ugaaaugucu caagaaggau     1140

uuucagcagc caucacauca aacggaccuu uacuaucaac cguuggcucc uaugauuggg     1200

cuggaggagu cuuccuuuau acuucuaaag aaaaauccac uuuuauaaau augacccggg     1260

uugauagcga caugaaugac gccuauuugg guuaugcagc ugcuauaaua cuacgaaauc     1320

guguccaaag uuuaguccua ggagcuccca gauaucagca uauugguuua guugcgaugu     1380

uuagacaaaa cacagguaug ugggaaucaa augcaaaugu uaaaggaaca caaauugggg     1440

cauauuucgg cgcuucccua uguucaguag acgucgauuc aaauggaucc acggauuuag     1500

uucucauagg ugcaccacac uauuaugaac aaacccgagg uggccaaguc uccguaugcc     1560

cccuaccacg cggccgugca cguuggcagu gcgacgcugu acuuuauggu gaacaaggac     1620

aaccuugggg acguuuugga gcagcccuaa cuguacuugg agacguuaau ggcgacaaau     1680

uaacggaugu ugcgaucggg gcaccaggcg aagaagauaa uagaggagcc guauacuuau     1740

uucauggcac aagcggcuca ggaauaucac cuucacauag ucaaagaaua gcaggaucaa     1800

aacuaucucc aagauuacaa uacuuugggc aaagucuaag cggcggacaa gaccuuacaa     1860

uggauggauu aguagaucua accguuggag cacaaggaca uguauuauua uuaagauccc     1920

aaccuguucu uagagucaaa gcuauuaugg aauuuaaccc uagagaagua gcucgcaaug     1980

uuuuugaaug uaaugaucag guuguuaaag guaaagaagc aggagaaguc cguguuuguc     2040

uucacguaca gaaaucaacu agggauagac uaagagaagg acaaauacaa aguguuguua     2100

cauaugauuu agcacuagac ucuggucgac cacauucaag agcaguuuuc aacgagacua     2160

aaaacucaac acgaagacaa acccagguau uagguuuaac acaaacuugc gaaacacuua     2220

aacuacaauu accuaauugc auagaagauc caguuucacc aauaguccua cgauuaaacu     2280

ucucauuagu uggcacccca cuguccgcuu ucggaaaccu acgucccguc cucgcagaag     2340

acgcacaaag acuauuuaca gcuuuauucc cuuuugaaaa gaauugcggc aaugauaaua     2400

uaugucaaga cgaucuuuca auuacuuuua guuuuauguc acuagauugc cuaguaguag     2460

gaggaccaag agaauuuaau guaacaguua caguacgcaa cgacggagaa gacucuuauc     2520

gaacacaagu uacauuuuuc uuuccauuag acuuaaguua ccgaaaagua ucaacccuuc     2580

aaaaucaacg aucacaaaga ucauggaggu uagccugcga aucggcauca uccacugaag     2640

uaucuggugc acucaaaagu acuucauguu ccauuaauca uccuauauuu ccugaaaauu     2700

ccgaaguaac cuuuaacaua acauuugaug uugauucaaa agccucucuc gguaauaaau     2760

uacuacuuaa agcaaacgug acauccgaaa auaacaugcc aagaacuaau aaaacggaau     2820

uucaauuaga auuaccuguu aaguacgcag ucuacauggu ugugacaagu cauggcguuu     2880

ccacaaaaua ucuuaacuuu acagcaagug aaaacacauc aaggguuaug caacaucaau     2940

aucaagucag uaaccuuggu caacgaagcc uaccaaucuc auuggucuuu cucgucccag     3000

uaagacuaaa ucaaaccgua auaugggauc gaccgcaagu uacuuucagu gaaaacuuaa     3060

guucuacaug ccacacaaaa gaaagacuuc caucucacuc ugacuuucua gcugaacuac     3120

gaaaagcucc cguuguaaac uguucuauag caguuuguca acguauacaa ugugauauuc     3180

cauucuuugg aauacaagaa gaguucaaug cuacauuaaa agguaauuua ucguuugauu     3240

gguacauuaa aacuagccau aaucauuuau uaauaguuuc uacugcagaa auccuguuua     3300

augauuccgu auucacucua uuacccggac aaggagcauu uguaagaucc caaaccgaaa     3360

caaaaguaga accuuuugaa guccccaacc cucuuccuuu aaucguugga ucaagcguug     3420

gcggacuauu acuuuuagcc uuaauaacgg cggcauuaua uaaauuagga uucuucaaac     3480

gccaauauaa agauaugaug ucugaaggug gaccuccugg agcagaacca caauaaggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  4436
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt6)

<400>  4436
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuuucacuaa aaacauuacc uuuccuacuu cuacuacacg      120

uacaaauauc aaaagcauuu ccagucucau caaaagaaaa aaacacaaaa acaguacaag      180

auuaucucga aaaauuuuac caauuaccau caaaucaaua ucaaucaaca cgaaaaaaug      240

gaacaaacgu aauaguugaa aaauuaaaag aaaugcaaag auucuuugga cucaauguca      300

caggcaaacc uaacgaagaa acacuagaca ugaugaaaaa accaagaugc ggaguaccag      360

acucaggagg auucauguua accccaggca acccuaaaug ggaaagaaca aaucuaacau      420

acagaauacg aaacuauaca ccacaacuau ccgaagcaga agucgaaaga gcaauaaaag      480

acgcuuuuga acuuugguca guagccuccc cacuaauauu cacacgaaua ucacaaggag      540

aagccgacau caacauagca uuuuaucaac gagaccacgg agacaauucc cccuucgacg      600

gaccaaaugg aauacuagca cacgcauucc aaccuggaca aggaauagga ggagaugcac      660

auuucgacgc agaagaaaca uggacaaaca caucagcaaa cuacaaccua uucuuagucg      720

cagcacacga auucggacau ucucuaggac uagcccauuc aucugacccc ggcgcacuaa      780

uguauccaaa cuacgcauuu agagaaacau ccaacuacuc ccuaccccaa gacgauauag      840

augguaucca agcaauauac ggacuauccu caaauccaau acaaccaaca ggccccucua      900

caccaaaacc augcgaccca ucccuuacau ucgacgcaau aacaacccuc cgaggagaaa      960

uauuauucuu uaaagacaga uacuucugga gaagacaccc ucaacuccaa cgaguugaaa     1020

ugaacuucau aucuuuauuu uggccaucuc uaccaacagg gauccaagca gcuuacgaag     1080

auuuugaucg cgacuuaaua uuuuuauuca aaggaaauca auacugggca uuaucaggau     1140

augauauacu acaaggauac cccaaagaca uaucaaauua uggauucccc uccucagucc     1200

aagccaucga cgcugcagua uucuaccgau caaaaaccua cuucuuugua aaugaccaau     1260

uuuggagaua cgauaaucaa cgucaauuca uggaaccugg uuauccaaaa ucaauaucug     1320

gcgcauuucc cggaauagaa agcaaaguag acgcagucuu ucaacaagaa cacuucuucc     1380

acguauuuag cggaccaaga uacuacgccu uugacuuaau agcacaaaga guaacacgag     1440

uugcaagagg aaacaaaugg cuaaacugua gauacggaua aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  4437
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt6)

<400>  4437
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agucuauggc aaccauuagu auuaguuuua cuuguacucg      120

guuguugcuu cgcugcaccu agacaacguc aaucaacccu cgugcucuuu ccaggagauc      180

uucgaacuaa uuuaacagau agacaauuag cagaagaaua uuuauauagg uauggcuaua      240

cacgaguagc ugaaaugcga ggagaaagua aaagccuagg accugccuua uuacuacuac      300

aaaaacaacu aucauuacca gaaacuggag aauuagacuc cgcuacucua aaagcaaugc      360

gcaccccacg uugcggagua ccagauuuag gacgauuuca aacauuugaa ggagauuuaa      420

aauggcauca ucacaauaua acauacugga uucaaaacua cagugaagau uuacccaggg      480

caguaauaga cgaugcauuu gcaagggcau uugcauuaug gucagcuguu acuccacuca      540

cuuucacuag aguuuacagu agagaugcag auaucguaau acaauuugga guagcagaac      600

acggcgacgg auacccauuc gacgguaaag auggacuacu agcucaugcc uucccaccag      660

guccagguau acaaggagac gcacauuuug augaugauga auuauggagu uuaggcaagg      720

gaguugucgu accaacucga uuuggaaaug cugauggugc agcuugccau uuucccuuua      780

uuuucgaagg gagaucguau ucagcuugca caacagacgg aagauccgau ggucuaccau      840

ggugcucuac aacagcuaac uaugacacag acgauagauu cggauucugc ccauccgaac      900

gauuauauac ucaagaugga aaugcagacg guaaaccaug ucaauuccca uuuauauucc      960

aaggacaauc auauagcgcu ugcacaacag auggaagaag cgauggauac agauggugcg     1020

caacaacagc uaacuaugau cgagacaaac uauuuggauu uuguccaaca cgugcugauu     1080

ccacaguaau gggaggaaau ucugcuggug aacuaugugu auucccauuu acauuccuug     1140

guaaagaaua cucuacaugu acaagcgaag gcagaggcga cggaagacuu uggugugcua     1200

caacaucuaa uuuugauagu gauaaaaaau ggggauucug uccagaccaa ggauacucau     1260

uauuucuagu agcugcacau gaauuuggac augccuuagg auuagaucau aguucuguac     1320

cagaagcucu gauguauccu auguaccgau ucacugaagg accaccacuc cauaaagacg     1380

auguuaaugg aauaagacau uuguacggac ccaggccaga accagaacca agaccaccaa     1440

caacaacaac uccucaaccg acagcaccac caacaguuug uccaacagga ccccccacag     1500

uacauccauc agaaagaccu acagcaggac caacaggucc gccaucagcc ggaccaacug     1560

gaccuccaac agcaggcccc uccacagcaa caacaguacc auuaucacca guagaugaug     1620

caugcaaugu aaauauauuu gaugcuauag cagagauagg caaucaacua uaucucuuua     1680

aagacggaaa auauuggaga uucucagagg gcagaggauc aagaccccaa ggaccauuuu     1740

uaauugcaga uaaauggcca gcuuuaccaa ggaaauuaga uucagucuuu gaagagcgcc     1800

ucucaaaaaa auuauuuuuu uucucaggaa gacaagucug gguuuauacc ggagcauccg     1860

uauuaggacc aagaagauua gacaaauuag guuuaggugc ugaugucgca caaguuacag     1920

gagcuuuacg aagcggucga ggaaaaaugc uacuguucuc ugguagaaga cuauggagau     1980

uugacguaaa agcgcaaaug guagacccuc gaagcgcuag ugaaguagau agaauguucc     2040

cugguguacc ucuugacacc caugacguuu uucaauacag agaaaaagca uauuuuugcc     2100

aagaucgcuu cuacuggcga guuaguucac guagcgaacu aaaucaagua gaccaaguug     2160

gauaugucac auacgauaua cuacaauguc cagaagacua aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  4438
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt6)

<400>  4438
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacccaggug uacuugcagc cuucuuauuu uuaucaugga      120

cucacuguag agcacuccca cuaccaucag gaggagacga agaugauuua ucagaagaag      180

accuccaauu cgcagaaaga uaucuaagau cuuacuauca cccaacaaac uuagcaggua      240

uacuaaaaga aaacgcagca ucaucaauga cagaaagacu aagagaaaug caaucauucu      300

uuggauuaga aguaacagga aaacuagaug auaauacacu agacguaaug aaaaaaccca      360

gaugcggagu accugaugua ggagaauaca acguauuccc aagaacacua aaauggucaa      420

aaaugaaucu aacauacaga aucguaaacu auaccccaga caugacacau agugaaguag      480

aaaaagcauu caaaaaagca uucaaaguau ggucagacgu aacaccauua aacuucacca      540

gacuucacga uggaauagca gacauuauga uuucauuugg cauaaaagaa cauggcgacu      600

ucuacccauu cgacggucca agcgguuuac uagcccaugc auucccaccu ggaccuaacu      660

auggcggaga cgcacacuuu gacgaugacg aaacauggac caguucaagu aaaggauaca      720

aucuauuuuu gguagcugcc cacgaauucg gccacucacu aggacuagac cauucaaaag      780

acccuggugc auuaauguuc ccaauauaua ccuauacagg aaaaucacau uucauguuac      840

cagaugauga uguacaaggc auccaaucau uauacggccc aggagacgaa gauccaaacc      900

caaaacaccc aaaaacacca gacaaaugcg acccuucacu aucucuagac gcaauaacuu      960

cuuuaagagg agaaacaaug auauucaaag aucgauucuu cuggagacuu cacccacaac     1020

aaguagaugc agaacuauuc uuaacaaaau cuuucuggcc agaacuacca aaccguaucg     1080

acgcagcaua ugaacaccca ucacaugacu uaauauuuau auuuagagga cgaaaauuuu     1140

gggcauuaaa cggauaugau auauuagaag gauacccuaa aaaaauauca gaacucggau     1200

uaccaaaaga aguuaaaaaa auaucggcag cuguacacuu cgaagacaca ggcaaaaccc     1260

uauuauuuuc aggaaaccaa guauggcgau augacgacac aaaucauaua auggauaaag     1320

auuacccaag auuaauagaa gaagauuucc caggaauagg ugacaaagua gacgcaguau     1380

acgaaaaaaa ugguuacaua uauuuuuuua acggacccau acaauucgaa uacucaauau     1440

ggucaaacag aauaguacga gucaugccag caaauucgau acuuuggugc uaaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4439
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt6)

<400>  4439
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacaccaa acacaacaga agacuacgau acaacaacug      120

aauucgacua cggagacgca acaccauguc aaaaagucaa cgaacgagca uucggagcac      180

aauuacuacc uccacuauac ucauuaguau uuguaauagg cuuagucgga aacauacuag      240

uaguacuagu uuuaguucaa uacaaaagac uaaaaaacau gacaucuaua uacuuacuaa      300

acuuagcaau aucagaucuu cuauucuuau ucacccuucc auucuggaua gacuacaaau      360

uaaaagacga cuggguauuc ggcgacgcaa ugugcaaaau auuauccgga uucuauuaca      420

caggacuaua cucagaaaua uuuuucauaa uacuccuaac aauagacaga uaccuagcaa      480

uaguucacgc aguauucgcu uuaagagcaa gaaccguaac auucggaguu auaacaucaa      540

uuauaaucug ggcacuagcc auacuagccu caaugccagg acuauacuuc ucuaaaacuc      600

aaugggaauu cacacaccau acauguucac uccacuuucc ccaugaaucc uuaagagaau      660

ggaaacucuu ccaagcacua aaauuaaacu uauucggacu aguauuacca cuacuaguaa      720

ugauaauaug cuacacagga auuauaaaaa uccuacuuag aagaccaaac gaaaaaaaau      780

caaaagcagu cagacuaaua uucgucauaa ugauaaucuu uuuuuuauuc uggacaccuu      840

acaaucucac uaucuuaaua ucaguuuucc aagacuuccu auucacacac gaaugugaac      900

aaucaagaca cuuagacuua gcaguacaag ucacugaagu aauagcauac acacacugcu      960

gcguaaaccc aguaaucuac gcauucguag gagaaagauu uagaaaauac cuaagacaac     1020

uauuccacag aagaguugcu guacaccuag uaaaaugguu acccuucuua ucagucgauc     1080

guuuagaaag agucucauca acaucacccu caacagguga acacgaacua ucagccggau     1140

uuuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  4440
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt6)

<400>  4440
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agaacauuag caugcuuauu acuauuagga uguggauacu      120

uagcacacgu auuagcggaa gaagcagaaa uaccaagaga aguaauagaa agacuagcac      180

gaucacaaau acacucaaua agggaccuac aaagauuacu agaaauagac ucaguaggaa      240

gcgaagacuc acuagacaca ucauuaagag cacacggagu acacgcaaca aaacacguac      300

cagaaaaaag accacuacca auaagaagaa aaagaagcau agaagaagca guaccagcag      360

uaugcaaaac aagaacagua auauaugaaa uaccacgauc acaaguagac ccaacaucag      420

caaacuucuu aauauggcca ccaugcguag aagugaaaag augcacaggc ugcugcaaca      480

caucgucagu aaaaugccaa ccaagcagag uacaccacag aucaguaaaa guagcuaaag      540

uagaauacgu aagaaaaaaa ccaaaacuaa aagaaguaca aguaagacua gaagaacacc      600

uagaaugcgc augcgcaaca acaagccuaa acccagacua ccgagaagaa gauacaggaa      660

gaccgcgaga aaguggaaaa aaacgaaaaa gaaaaagacu aaaaccaacc uaaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  4441
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt6)

<400>  4441
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aauagaugcu gggcacuauu cuuaagcuua uguugcuacu      120

uaagacuagu aucagcagaa ggagauccaa uaccagaaga auuauacgaa augcuaagcg      180

accacucaau cagaagcuuu gacgauuuac aaagacuacu acauggagau ccaggagaag      240

aagacggagc agaacuagac uuaaauauga caagaucaca cucaggagga gaauuagaau      300

cacuagcaag aggaagaaga agucuaggau cacuaacaau agcggaacca gcaaugauag      360

cagaauguaa aacacgaaca gaaguauucg aaauaucaag aagauuaaua gacagaacaa      420

augcaaacuu ccuaguaugg ccaccaugcg uagaaguaca aagaugcuca ggauguugca      480

auaacagaaa cguacaaugu aggccaacac aaguacaauu aagaccagug caaguaagaa      540

aaauagaaau aguacguaaa aaaccaauau uuaaaaaagc aacaguaaca cuagaagacc      600

aucuagcaug uaaaugcgaa acaguagcag cggccagacc aguaacaaga agcccaggag      660

gaagucaaga acaaagagca aaaacaccac aaacuagagu uacaauaaga acaguaagag      720

uaagaagacc accaaaagga aaacauagaa aauucaaaca cacacaugau aaaacagcac      780

uaaaagaaac cuuaggagca ugaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  4442
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt6)

<400>  4442
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcuuauucg gacuacuacu ccuuacuuca gcacuagcag      120

gacaaagaca aggaacacaa gcagaaucaa accuaagcuc aaaauuccaa uuuucaucaa      180

acaaagaaca aaauggagua caagauccac aacacgaaag gauuauuaca gucucaacaa      240

acggaaguau acacagucca agauucccac auacauaccc aagaaacaca guuuuagucu      300

ggcgacuagu agcaguagaa gaaaauguau ggauacaacu aacauucgau gaaagauucg      360

gauuagaaga cccagaagac gacauaugca aauaugacuu uguagaaguc gaagaaccaa      420

gugacgguac aauacuagga agauggugcg gaucaggaac aguaccaggc aaacaaauaa      480

guaaaggaaa ccaaauuaga auaagauucg uaucagauga auacuuucca ucagaaccag      540

gauucugcau acauuacaac auaguaaugc cacaauucac cgaagcaguu ucaccaucag      600

uuuuaccacc aagugcccuc ccauuagacc uacuaaacaa cgcaauaacu gcauucagua      660

cucuagaaga ccuaauaaga uaccuagaac cagaaagaug gcaauuagau cucgaagacc      720

uauauagacc aacauggcaa cuauuaggca aagcauuugu auucggaaga aaaucaagag      780

uaguagacuu aaaccuauua acagaagaag uaagacuaua cagcugcaca ccaagaaacu      840

uuucaguuuc aauaagagaa gaauuaaaaa gaacagauac aaucuucugg ccaggauguc      900

uauuagucaa aagaugcggc ggaaacugcg caugcugccu acauaacugc aacgaaugcc      960

aaugcguacc aaguaaagua acaaaaaaau accacgaagu auuacaacua agaccaaaaa     1020

cuggaguaag aggucuacac aaaucacuaa cugacguagc auuagaacau cacgaagaau     1080

gugacugcgu cugcagagga ucaacaggag gauaaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  4443
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt6)

<400>  4443
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagacuaa uauucguaua cacacucaua ugcgcaaauu      120

ucugcucaug uagagacaca ucagcaacac cacaaucagc aucaauaaaa gcacuaagaa      180

acgccaaccu aagacgagac gauuuauaca gaagagacga aacaauacaa guaaaaggua      240

acggauaugu acaaucacca agauucccaa acaguuaccc aagaaaucua cuacuaacau      300

ggagacuaca cucacaagaa aacacaagaa uacaacuagu auuugacaac caauuuggac      360

uagaagaagc ugaaaacgac auauguagau augacuucgu agaaguagaa gacauaagug      420

aaacaucaac aauaauuaga ggaagauggu gcggccacaa agaaguacca ccccgaauaa      480

aaucaaggac aaaccaaauc aaaauaacuu ucaaaucaga cgacuacuuu guagcaaaac      540

caggcuuuaa aauauacuau agcuuacuag aagacuucca accagcagcc gcaagugaaa      600

caaacuggga aagcguaaca ucaagcaucu caggaguaag cuauaacuca ccaucaguaa      660

cagacccaac acuaauagca gacgcauuag acaaaaaaau agcagaauuc gacacaguag      720

aagauuuauu aaaauacuuc aacccagaau cauggcaaga agaccuagaa aauauguacc      780

ucgacacacc aagauauaga ggaagaagcu aucacgauag aaaaucaaaa guagaccuag      840

acagacuaaa ugacgacgcu aaacgauaua guuguacacc aagaaacuac agugucaaca      900

uacgagaaga acuaaaacua gcaaacguag uauucuuucc acgaugucua cuaguacaaa      960

gauguggagg aaacugcgga ugcggaacag uaaauuggag aucaugcacc ugcaacagcg     1020

gaaaaacagu uaaaaaauac cacgaaguac uacaauucga accuggccac auaaaacgaa     1080

ggggaagagc aaaaaccaug gcacuaguag auauccaacu agaucaucac gagagaugug     1140

acuguauaug uaguucaaga ccaccaagau aaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  4444
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt6)

<400>  4444
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaacacacu caaaauuccc agcagcagga augucaagac      120

cauuagacac aucauuaaga cuaaaaacau ucucaucaaa aucagaauau caacuaguag      180

uaaacgcagu aagaaaacua caagaaucag gauucuacug gucagcagua acaggaggag      240

aagccaaccu acuccuauca gcagaaccag caggaaccuu ccuaauaaga gacucaucag      300

accaacgaca cuucuucaca cuaucaguaa aaacacaauc cggaacaaaa aaccucagaa      360

uacaaugcga aggaggauca uucucacuac aaucagaccc acgcuccaca caaccaguac      420

caagauucga cugcguacua aaacuaguac accacuacau gccaccacca ggagccccau      480

cauuuccauc accaccaaca gaaccaucau cagaaguacc cgaacaacca ucagcacaac      540

cacuccccgg aucaccacca agaagagcau acuacauaua cucaggagga gaaaaaauac      600

cauuaguacu auccagacca uuaucuucaa acgucgcaac acuacaacau cuaugcagaa      660

aaacaguaaa cggacacuua gacucauacg aaaaaguaac ccaacuacca ggccccauac      720

gagaauuccu agaccaauac gacgcaccac uauaaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  4445
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt6)

<400>  4445
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaccaucag caggacaauu agcauuauuc gcauuaggaa      120

uaguauuagc agcaugucaa gcauuagaaa auucaacauc accacuauca gcagauccac      180

caguagcagc agcuguagua ucacauuuua augacugucc agauucacau acucaauucu      240

guuuucaugg aacauguaga uucuuaguac aagaagacaa accagcaugu guaugucauu      300

caggauaugu aggagcaaga ugugaacaug cagauuuauu agcaguaguc gcagcaucac      360

aaaaaaaaca agcaauaaca gcauuaguag uaguaucaau aguagcauua gcaguacuaa      420

uuauaacaug uguacuaaua cauuguuguc aaguaagaaa acauugugaa uggugcagag      480

cauuaauaug uagacaugaa aaaccaucag cauuauuaaa aggaagaaca gcauguuguc      540

auucagaaac aguaguauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  4446
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt6)

<400>  4446
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaccuagcg gacucagauu auuacccuua cuacucccac      120

uccuauggcu acuaguacua acuccaggaa gaccagcagc aggacuaagu acauguaaaa      180

cuauagacau ggaauuagua aaaagaaaaa gaauagaagc cauacgugga caaauccuau      240

cuaaauugag acuagccuca ccuccaucac aaggagaagu accaccagga ccccuacccg      300

aagcaguacu agcacuauac aacucaacaa gagauagagu agcaggagaa ucagcagaac      360

cagaaccaga accagaagca gauuauuacg caaaagaagu aacacgcgua uuaaugguag      420

aaacacauaa cgaaauauau gauaaauuca aacaaucuac acacucuaua uacauguucu      480

uuaauacauc agaacucaga gaagccguac ccgaaccagu auuauuauca agagcagaac      540

uaagacuucu aagacuaaaa cucaaaguug aacaacacgu agaacuauac caaaaauacu      600

caaacaauuc uuggagauau uuaucuaaca gacuacuagc ccccucagac uccccugaau      660

ggcuaucauu cgacguaaca ggaguaguca gacaaugguu aucuagagga ggagaaauag      720

aaggauuccg acuuucagca cacuguucuu gugauagucg cgacaacaca uuacaaguag      780

acauaaacgg uuucacaacu ggacguagag gagaccuugc aacaauacau gguaugaaca      840

gaccauucuu acuacuaaug gcaacaccac ucgaacgagc acaacaucua caauccucac      900

gccacagacg agcccuagac acaaacuacu gcuucucauc aaccgaaaaa aauuguugcg      960

uaagacaauu auacauagau uucagaaaag accuaggaug gaaauggaua caugaaccua     1020

aaggauacca cgccaauuuu uguuuaggcc cauguccaua cauaugguca cuagacacac     1080

aauacucuaa aguauuagcu cuauacaacc aacacaaccc aggcgcauca gcagcaccau     1140

gcuguguucc acaagcuuua gaaccauuac caaucguaua uuacguagga agaaaaccca     1200

aaguagaaca auuaucaaac augauaguca gaucauguaa augcucuuaa ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  4447
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt6)

<400>  4447
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauuacugcg uacuaucagc auuccuaaua cuacaccuag      120

uaacaguagc auuaucccua ucaacuugcu ccacccuaga cauggaccaa uuuaugagaa      180

aacgcauaga agcaauaaga ggacaaauuu uaucaaaacu caaacuaaca agcccaccag      240

aagacuaccc agaaccagaa gaaguaccac cggaagucau uucaauauac aauucaacaa      300

gagaccuacu acaagaaaaa gcaucaagaa gagcugcagc augugaaaga gaacgcagcg      360

acgaagaaua cuacgcaaaa gaaguauaca aaaucgacau gccuccauuc uucccaagcg      420

aaaacgcaau accaccaaca uucuaucgac cauauuuuag aauaguaaga uucgacgucu      480

cagccaugga aaaaaaugcu agcaauuuag uaaaagcaga auuuagaguu uucagacuac      540

aaaacccaaa agcacgaguc cccgaacaac gaauagaauu auaccaaaua cuaaaaucaa      600

aagaccuaac auccccaaca caaagauaca uagacucaaa aguaguuaaa acccgagcag      660

aaggcgaaug gcuaucuuuc gauguaacag acgcaguaca cgaaugguua caccacaaag      720

auagaaaccu agguuucaaa auaucucucc acugcccaug cugcacauuc guaccaucca      780

acaacuacau aauaccaaac aaaucugaag aauuagaagc aagauucgca ggaauagacg      840

guacaucaac cuacacauca ggagaucaaa aaacaauaaa auccacaaga aaaaaaaauu      900

caggaaaaac accacaccua cuacuaaugc uacuaccaag cuacagauua gaaucacaac      960

aaacaaacag acgaaaaaaa agagcacuag augcagcaua cugcuucaga aacguacaag     1020

acaacugcug ucuccgccca cuauacauag auuucaaacg agauuuagga uggaaaugga     1080

uacacgaacc caaaggauau aacgccaacu ucugcgcagg agcaugccca uauuuauggu     1140

cauccgacac ccaacacucc agaguccuau cucucuacaa caccauaaac ccagaagcau     1200

cagcaucacc cugcugugua ucccaagacu uagaaccacu uacaauauua uacuacauag     1260

gaaaaacacc aaaaauagaa caacuaucaa acaugauagu caaauccugu aaaugcucau     1320

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  4448
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt6)

<400>  4448
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaugcacu uacaaagagc auuaguugua cuagcacuuc      120

ucaacuuugc aacaguauca cuaucauuau caaccugcac aacacuagac uuuggacaca      180

uaaaaaaaaa acgaguagaa gccauaagag gacaaauacu aucaaaacua agacuaacau      240

caccaccaga accaaccgua augacacacg ucccauacca aguauuagcc cuauacaaca      300

guacaagaga acuacucgaa gaaaugcacg gagaacgaga agaaggaugc acucaagaaa      360

auacagaauc agaauacuac gcaaaagaaa uacacaaauu ugauaugaua caaggauuag      420

cagaacacaa ugaacuagcc guaugcccaa aaggaauaac aucaaaagua uuuagauuua      480

acguaucauc agucgaaaaa aaccgcacaa aucuuuucag agcagaauuu cgagugcuac      540

gaguaccaaa uccaucauca aaaagaaacg aacaacgcau agaacuauuu caaauccuac      600

gaccagacga acacauagca aaacaaagau acauaggagg caaaaaccuc cccacaagag      660

guaccgcaga augguuauca uucgauguca ccgacacagu acgagaaugg uuacuaagaa      720

gagaaucaaa ccuaggcuua gaaauaucaa uccacugccc augccacacc uuucaaccaa      780

auggagacau auuagaaaac auacacgaag uuauggaaau aaaauucaaa ggaguagaua      840

augaagauga ccacggacga ggugaucuug gaagacuaaa aaaacaaaaa gaccaccaca      900

acccacaucu aauauuaaug augauaccuc cacacagauu agacaacccc ggacagggag      960

gacaaagaaa aaaaagagca cuagauacaa acuauugcuu cagaaaccua gaagaaaacu     1020

gcugcgucag accuuuauac auagauuuca gacaagaucu cggauggaaa uggguccacg     1080

aaccaaaagg auacuaugca aacuuuugcu ccggccccug cccauaucua cgaucagcag     1140

acacaacaca cucaacagua cucggacuuu auaacacucu aaaccccgaa gcauccgccu     1200

ccccaugcug uguuccacaa gacuuagaac cacuaacaau auuauacuau guaggacgaa     1260

caccaaaagu ugaacaauua agcaacaugg uaguaaaauc augcaaaugu agcuaaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4449
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt6)

<400>  4449
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacccguag cugucugggc agcauuagca guuggauuag      120

aauuaugggc agcugcccac gcacuaccag cccaaguagc auucacaccu uacgccccag      180

aaccuggauc uaccugcaga cuaagagaau auuacgauca aacagcucaa auguguuguu      240

caaaauguuc accaggccaa caugcaaaag uauucuguac aaaaacauca gauacaguau      300

gugauucaug cgaagauuca acuuauacac aauuauggaa uuggguuccc gaaugccuau      360

ccuguggauc aagauguuca ucagaucaag uagaaaccca agcauguaca agagaacaaa      420

auagaauaug uacaugcaga ccagguuggu auugugcacu aagcaaacaa gaaggaugca      480

gauuaugugc cccauuaaga aaaugucgac caggcuucgg aguagcacga ccuggaaccg      540

aaaccucuga uguaguaugc aaaccaugug caccaggaac auuuucaaac acaacaucuu      600

caacagacau augcagacca caccaaauau guaacguugu agcaauaccu ggcaaugccu      660

caauggaugc aguuuguaca ucaacauccc caacaagauc uauggcacca ggagccguac      720

auuuaccaca accaguuagu acucgaucac aacauaccca acccacaccc gaaccaucca      780

cugcuccguc caccucauuc cuacuaccaa ugggacccuc uccaccagcu gaagguucua      840

caggagacuu cgcacuacca guuggauuaa uaguaggagu aaccgcacua ggacuucuaa      900

ucauaggagu aguuaauugu guaaucauga cucaaguuaa aaaaaaaccu uuauguuuac      960

aacgagaagc aaaaguacca cauuuaccgg cagauaaagc aagaggaacu caaggaccag     1020

aacaacaaca ucuauuaauu acagcuccau caucaucauc aucaucacua gaaucaucag     1080

cuucagcacu ugaucgaaga gcaccuacac guaaccaacc acaagcacca gguguggaag     1140

cuucaggugc aggagaagca agagcaagua caggaucauc agacaguuca ccaggagguc     1200

auggaacaca aguaaaugua acuuguauag uaaaugucug uagcucauca gaucauucau     1260

cccaaugcuc aucucaagcc uccucaacaa ugggagacac agauuccucu ccaucagaau     1320

caccaaaaga cgaacaagua ccauuuucaa aagaagaaug ugccuucaga ucacaacuag     1380

aaacaccaga aacuuuauua ggaucaacug aagaaaaacc gcuacccuua ggaguaccag     1440

acgccggaau gaaacccucu uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  4450
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt6)

<400>  4450
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaguaauga gauuauuucc auguuuucua caauuauuag      120

caggauuagc acuaccagca guaccaccac aacaaugggc auuaucagca ggaaauggaa      180

guucagaagu agaaguagua ccauuucaag aagugugggg aagaucauau uguagagcau      240

uagaaagauu aguagaugua guaagugaau auccaaguga aguagaacau auguuuucac      300

caaguugugu aaguuuauua agauguacag guuguugugg agaugaaaac cuacauugug      360

uaccaguaga aacagcaaau guaacaaugc aauuauuaaa aauaagaagu ggagauagac      420

caucauaugu ugaauuaaca uuuagucaac auguaagaug ugaaugcaga ccacuaagag      480

aaaaaaugaa accagaaaga agacgaccaa aaggaagagg aaaaagaaga agagaaaaac      540

aaagaccaac agauugucau uuauguggag augcaguacc aagaagauaa ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  4451
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt6)

<400>  4451
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagauagac aaacugauac agcaccgagu ccgaguuauc      120

auuuauuacc aggaagaagg agaacaguag augcagcagc aucaagagga caaggaccug      180

aaccagcacc aggaggaggg guagaaggag uuggagcuag aggaguagca uuaaaauuau      240

uuguccaguu auuaggaugc aguagauuug gaggagccgu aguaagggca ggagaagcag      300

aaccaucagg ggcagcacga agugcaucaa guggaagaga agaaccacaa ccagaagaag      360

gagaagaaga agaggagaaa gaagaagaaa gaggaccaca auggcggcug ggugcgagaa      420

aaccaggaag uuggacagga gaagcagcag uaugcgcaga uucagcuccc gcagcgagag      480

caccucaagc auuagcaaga gcaagcggaa gaggaggaag aguagcaaga agaggagcag      540

aagaaucagg gccaccucau agcccaagua gaagggguag ugcaaguaga gcaggaccag      600

gaagagcaag cgaaacaaug aauuuuuuau uaagcugggu acauugguca uuagcgcuau      660

uacuauauuu acaucaugca aaauggagcc aagcagcacc aauggcagaa ggaggagguc      720

aaaaccauca cgaaguagua aaauuuaugg auguuuauca aaggucauac ugccacccaa      780

uagaaacacu aguagauaua uuucaagaau acccagacga aauagaauau auauuuaaac      840

caagcugugu accacuaaug agauguggug gauguugcaa cgaugaagga cuagaaugug      900

uaccaacaga agaaucuaau auaacaaugc agauaaugag aauaaaacca caccaaggac      960

aacauauagg agaaaugagu uuuuuacaac auaauaaaug ugaauguaga ccaaaaaagg     1020

auagagcaag gcaagaaaaa aaaucaguaa gaggcaaagg aaaaggacaa aaaaggaaaa     1080

gaaaaaagag cagauauaaa aguuggagcg uguauguagg agcaagaugc ugucuaaugc     1140

cauggucacu accaggaccu cauccaugug gaccauguag ugaacgaaga aaacaucuau     1200

uuguacagga uccacaaaca uguaaaugua gcuguaaaaa uacagauagu agauguaaag     1260

caaggcaauu agaauuaaau gaaaggacuu guagaugcga uaaaccuaga agguagggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4452
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt6)

<400>  4452
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuucuau uaagcugggu acauugguca cuugcauuau      120

uacuauauuu acaucacgca aaauggagcc aagcagcacc aauggcagaa ggaggaggac      180

aaaaccauca cgaaguagua aaauuuaugg auguauauca aaggaguuac ugccauccaa      240

uagaaacacu aguggacaua uuccaagaau auccagauga aauagaauau auauuuaaac      300

caagcugugu accacuaaug agauguggag gaugcuguaa cgaugaagga cuagaaugcg      360

uaccaacaga agaaagcaau auaacaaugc aaauaaugag aauaaaacca caccaaggac      420

aacacauagg agaaauguca uucuuacaac auaacaaaug cgaaugcaga ccaaaaaaag      480

aucgagcaag acaagaaaaa aaaucaguaa gaggaaaagg aaaaggacaa aaaagaaaaa      540

gaaaaaaaag cagauacaaa aguuggagcg uauacguagg agcaagaugu ugcuuaaugc      600

cauggucacu accaggacca cacccaugcg gacccuguag cgaaagaaga aaacaucuau      660

ucguacaaga cccacaaaca ugcaaaugcu caugcaaaaa cacagacuca agauguaaag      720

caagacaacu agaacuaaau gaaagaacau guagauguga caaaccaaga agauaaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  4453
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt6)

<400>  4453
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaccauuac uaagaagacu auuacuagca gcauuauuac      120

aacuagcacc agcacaagca ccaguaucac aaccugaugc accaggacau caaagaaaag      180

uaguaucaug gauagaugua uauacaagag caacaugcca accaagagaa guaguaguac      240

cacuaacagu agaauuaaug ggaacaguag caaaacaauu aguacccuca ugcguaacag      300

uacaaagaug cggagguugu uguccagacg auggacuaga auguguaccu acaggucaac      360

aucaaguaag aaugcaaaua uuaaugauaa gauacccaag uucacaauua ggagaaaugu      420

cauuagaaga acauucacaa ugcgaaugua gaccaaaaaa aaaagacuca gcaguaaaac      480

cagacagagc agcaacacca caccauagac cucaaccaag aucuguacca ggaugggacu      540

cagcaccagg agcuccauca ccagcagaca uaacucaucc aacaccagca ccaggacccu      600

cagcacaugc agcuccauca acuacaucag cauuaacacc aggaccagca gcagcugcug      660

cagacgcagc agccucauca guagcaaaag gaggagcaua aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  4454
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt6)

<400>  4454
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuauuag gauuuuucuc aguagcaugu ucauuacuug      120

cagcagcauu acuccccgga ccaagagaag caccagcugc agcagcagca uucgaaucag      180

gacuagaccu aagcgaugca gaaccagacg caggagaagc aacagcauau gcaaguaaag      240

accuagaaga acaauuaaga aguguaucau caguagacga acuaaugaca guacucuacc      300

ccgaauacug gaaaauguac aaaugccaau uaagaaaagg aggauggcaa cacaacagag      360

aacaagcuaa ccuaaacuca agaacugaag aaacaauaaa auuugcagca gcccacuaca      420

auacagaaau auuaaaauca aucgauaacg aauggcgaaa aacacaaugu augccaagag      480

aaguuuguau agacguagga aaagaauuug gaguugcaac aaauacauuu uuuaaaccac      540

caugcgucuc aguauacaga ugcggaggau gcugcaauag cgaaggauua caauguauga      600

auacaucaac aagcuacuua agcaaaacac uauuugaaau aacaguaccc uuaucacaag      660

gacccaaacc aguuacaaua aguuuugcaa aucauacuuc augcagaugu augaguaaau      720

uagauguuua ucgccaagua cauucaauaa uacgacgcag ucuaccagca acauuaccac      780

aaugccaagc ugcaaauaaa acaugcccaa cuaauuauau guggaauaau cacaucugca      840

gaugucuugc acaagaagac uucauguuuu ccucagaugc aggagacgau ucaacagacg      900

gcuuccacga cauaugugga ccaaauaaag aacuagauga agaaacaugu caaugcgucu      960

gcagagcagg auuaagacca gcaucaugug gaccacacaa agaauuagac aggaauuccu     1020

gccaaugugu auguaaaaau aaacuauuuc caucacaaug cggagccaau cgagaauucg     1080

acgaaaauac augccaaugu gucuguaaaa gaaccugucc cagaaaucaa ccauuaaacc     1140

cuggaaaaug ugccugugaa ugcacagagu caccacaaaa auguuuacua aaaggaaaaa     1200

aauuccauca ucaaacaugc uccuguuaca gaagacccug cacaaacaga caaaaagcau     1260

gcgaaccagg auucagcuac agugaagaag uaugcagaug uguaccauca uauuggaaac     1320

gaccacaaau gucauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  4455
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt6)

<400>  4455
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagaau ggguaguagu aaacguauuc augaugcuau      120

acguacaauu aguacaaggu uccucaaacg aacacggccc aguaaaaaga ucaucccaaa      180

gcacacuaga aagaucugaa caacaaauaa gagcagcauc uucacuagaa gaacuuuuaa      240

gaauaacaca cucagaagac uggaaacuau ggagaugcag acuaagacua aaaucauuca      300

caucuaugga cagcaggucc gcaagucaca gaucaaccag auucgccgca acauuuuaug      360

acauagaaac acucaaagua auagacgaag aauggcaaag aacacaaugc aguccaagag      420

aaacaugugu agaaguagcc ucagaacuag gaaaaagcac uaacacauuc uucaaaccac      480

caugcguaaa uguauucaga ugcggcggau guugcaacga agaaucucuc auauguauga      540

acacaaguac aucauacauc ucaaaacaac uauucgaaau aucaguccca uuaacaucag      600

uaccagaacu aguaccagua aaaguagcaa accacacagg auguaaaugc cuaccaacag      660

caccaagaca cccauacagu aucauaagaa gaucaaucca aauaccagaa gaagaccgau      720

gcucccacuc aaaaaaauua ugcccaauag acaugcuaug ggauucaaac aaaugcaaau      780

gcguacuaca agaagaaaac ccauuagcag gaacagaaga ccacucucac uuacaagaac      840

cagcauuaug cggaccacau augauguucg acgaagauag augugaaugu guaugcaaaa      900

cuccaugccc aaaagaccua auacaacacc caaaaaacug cucauguuuc gaaugcaaag      960

aaucucuaga aacaugcugc caaaaacaca aauuauuuca cccagacaca ugcucaugcg     1020

aagacagaug cccuuuccac accagaccau gugccagcgg aaaaacagca ugugcaaaac     1080

acuguagauu uccaaaagaa aaacgagcag cccaaggacc acacucaaga aaaaauccau     1140

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  4456
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt7)

<400>  4456
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgaug agaccggcuu cgaacacucc gggcuguggg      120

ugaguguccu cgccggucug uugcugggcg caugccaggc ccaucccauc ccagacagcu      180

ccccgcuccu gcaauuuggg ggccagguga ggcagcggua cuuguauacu gaugacgcgc      240

agcaaaccga ggcccaccug gaaauucgcg aggaugguac gguagggggc gcagccgacc      300

agagucccga aagccuccug cagcugaagg cacucaaacc aggcgugauc cagauucugg      360

gggucaagac uuccagguuc uugugucaac ggcccgaugg ugcccuguac ggcagccucc      420

auuuugaccc agaggcgugc uccuuccgcg agcugcuguu ggaagauggg uauaacgugu      480

accagaguga ggcccacggc cucccccugc aucugccagg uaauaaaagc ccgcacaggg      540

accccgcacc acgggggccc gcccgcuuuc ucccacugcc cggcuugccg cccgcccugc      600

cagaaccccc aggcauccuc gcaccccagc caccggaugu gggguccagc gacccccuga      660

guauggucgg uccaucccag ggcaggagcc ccuccuaugc caguugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  4457
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt7)

<400>  4457
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc ccccacugcu ccuguugcug uucuggggcg      120

uggucuccca uaguuucccg gccacccucg agacucagga acaagacgug gaucugguac      180

agaaguacuu ggagaaauau uacaaccuga agaaugacgg gaggcaagug gaaaaacggc      240

gcaacagcgg ucccgucgug gagaagcuca aacagaugca ggaauuuuuc ggccugaagg      300

ugaccgggaa gccagaugca gagacgcuga aagucaugaa gcagcccagg ugcggcgugc      360

cagacguagc ccaguuugug cucacugagg guaauccccg gugggaacag acccaccuga      420

ccuaucgcau cgagaacuac acuccagauu ugccgagggc ggacgucgau caugccauug      480

aaaaagcauu ccaacugugg uccaauguga cgccccucac cuuuacuaag gugagugagg      540

ggcaggccga caucaugauu agcuucgucc ggggcgauca ccgcgacaac uccccauuug      600

auggccccgg ggguaaucug gcacaugccu uccagccagg ccccgggauc ggcggugacg      660

cgcacuuuga ugaggacgaa agguggacca acaauuuccg ggaguauaac cugcaccgcg      720

uggccgcaca ugaauugggg cacagccucg gccuguccca uaguacugac auuggcgccc      780

ugauguaccc gagcuauacc uucuccgggg auguacagcu cgcccaagac gauaucgacg      840

guauccaggc aauuuacggc aggagccaga aucccgugca accaaucggg ccccagaccc      900

caaaagccug ugauaguaag cugacguuug acgcgauuac uaccauccgg ggcgagguca      960

uguucuuuaa agaucgcuuc uacaugagga cuaaccccuu uuauccagaa guggaguuga     1020

auuucauuuc cguguuuugg ccgcagcugc ccaacggucu cgaggccgca uacgaguucg     1080

ccgaccggga ugaaguccgc uuuuucaagg gcaauaagua uugggcagug caggggcaaa     1140

acguacugca cggcuaccca aaagacaucu auagcuccuu uggguucccc aggaccguga     1200

agcacauuga ugccgcccug agugaagaga acaccgguaa aacuuacuuu uucgucgcga     1260

auaaguauug gcgguacgac gaauacaaac gcagcaugga cccaggcuau cccaagauga     1320

ucgcacauga uuucccgggg aucggccaca agguggacgc cgucuuuaug aaagaugguu     1380

ucuuuuacuu cuuucauggc acgaggcagu auaaguucga cccaaaaacc aagcggauuu     1440

ugacucucca gaaagccaac uccugguuua auugcaggaa gaacugagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  4458
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt7)

<400>  4458
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc ccccacugcu ccuguugcug uucuggggcg      120

uggucuccca uaguuucgug cucaccgagg ggaacccgag gugggaacag acucaccuga      180

ccuaccggau cgagaauuau acgcccgacu ugccacgcgc cgauguagac caugcaauug      240

aaaaggccuu ucaacugugg agcaacguga cuccccucac cuucaccaaa gucuccgagg      300

gucaggcgga uaucaugauu aguuuuguga ggggcgacca ccgggauaau agcccauucg      360

acgggcccgg cgguaaccug gcccaugcau uucagccagg gccgggcauc ggcggggaug      420

cccacuucga cgaagaugag cgcuggacua auaacuuuag ggaguacaau cugcaccggg      480

uggcagccca ugaacucggu cacucccugg gcuugagcca uuccaccgac auuggggcgc      540

ugauguaucc caguuacacg uucagcggcg auguccagcu cgcccaagac gauaucgacg      600

guauccaggc aauuuauggg cgcucccaga acccagugca gcccaucggc ccacaaacuc      660

ccaaggccug cgacagcaaa cugaccuuug augccauuac uaccaucagg ggcgagguaa      720

uguucuucaa ggaccgguuu uacaugcgca ccaauccguu cuaucccgaa guggagcuga      780

acuuuauuag ugucuucugg ccacaguugc ccaaugggcu cgaggcagcc uacgaauuug      840

cggauaggga cgaggugcgg uucuuuaaag guaacaagua cugggccgug cagggccaga      900

auguccugca cggguaucca aaggauaucu acuccagcuu cggcuuuccc cgcacgguga      960

aacacauuga cgcagcccug uccgaagaga acacugguaa gaccuauuuc uuuguagcaa     1020

auaaauacug gagguaugau gaauacaagc ggaguaugga cccaggcuau ccgaaaauga     1080

ucgcccauga uuuccccggg aucggccaca agguggacgc cgucuuuaug aaagaugggu     1140

ucuucuacuu uuuccauggu acucgccaau acaaguuuga cccaaagacc aaaaggauuc     1200

ucacccugca gaaggcgaac agcugguuca acugucggaa aaauugagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  4459
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt7)

<400>  4459
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaaaaaca uccugaagau ucucauggac agcuacucca      120

aagagaguaa gauccagacc gugaggcggg ucacuagcgu gucccuguug gccguauauc      180

ugaccaugaa uacgaguagc cucgugcugg caaaacccau ugaaaacacu aaugauaccu      240

ccaucaagaa cgucgagaag uugcgcaaug ccccaaacga agagaauagc aaaaaggugg      300

aagacuccaa aaacgauaag guggagcacg ucaaaaauau ugaggaagcg aagguggagc      360

aaguagcccc ggaagugaaa aguaagagca cccugagguc cgcaagcauc gccaacacua      420

auagugagaa guacgacuuc gaguaucuca acggccuguc cuacaccgaa cugacgaauc      480

ucaucaaaaa cauuaagugg aaucagauca acgggcuguu uaacuauagc acugguuccc      540

agaaauucuu uggcgauaag aaucgggucc aggcaauuau caacgccuug caagagagug      600

ggcgcaccua cacugcgaau gacaugaaag gcauugaaac cuucaccgag gugcugaggg      660

ccgguuuuua ucucggguac uacaacgaug gccugagcua ucugaaugac cggaacuucc      720

aggauaagug cauccccgca augauugcca uccagaagaa uccaaacuuu aaauugggca      780

cggccgugca ggacgaaguc aucacuuccc ucgggaagcu gauugguaau gcaagcgcca      840

acgcggaggu gguaaauaac ugugugcccg uccugaaaca auuccgcgag aaucucaacc      900

aguacgcccc agauuaugug aagggcaccg cagugaauga acugaucaaa gggauugagu      960

uugacuucag uggcgccgca uacgaaaagg augucaagac uaugcccugg uaugguaaaa     1020

ucgacccauu uauuaacgag uugaaggccc uggggcucua cggcaacauc accuccgcca     1080

ccgaaugggc gagcgacgug ggcaucuauu accugaguaa auucgggcug uacuccacua     1140

auaggaacga uauuguacag agcuuggaga aggcagugga cauguauaaa uacgguaaga     1200

ucgccuucgu cgccauggag cggauuacgu gggauuauga cggcaucggg agcaauggca     1260

agaaagugga ucaugacaag uuucucgaug acgcagaaaa acacuaccug ccgaagaccu     1320

auacuuucga uaacgguacc uuuauuaucc gcgccggcga caaagucucc gaggaaaaga     1380

ucaaaaggcu guacugggcg agucgggagg uaaagagcca guuccaucgc guggugggga     1440

augauaaggc ccucgaagug ggcaacgcag acgacguccu gaccaugaaa auuuuuaauu     1500

cccccgagga guauaaguuc aacacuaaua ucaacggggu gagcacggau aaugguggcu     1560

uguacauuga accaaggggg accuuuuaca cuuaugagcg gacuccccaa cagaguaucu     1620

ucucccugga ggaacucuuu cgccacgagu acacccauua ucugcaggcc agguaccugg     1680

ucgacggcuu guggggucaa ggcccauucu augagaaaaa ccggcucacc ugguuugaug     1740

aagggacggc agaguucuuu gccggcagca cccgcacuuc cggggugcug cccaggaaga     1800

guauucuggg cuaccucgcc aaagacaagg uggaucaccg guauagccug aagaaaaccu     1860

ugaacuccgg uuacgacgau agcgacugga uguucuacaa uuauggguuc gcaguagccc     1920

acuaccugua ugaaaaggau augccgacuu uuaucaaaau gaauaaggcg auucucaaca     1980

ccgacgugaa aaguuacgau gaaaucauca agaagcuguc cgacgaugcc aacaaaaaua     2040

cggaguauca gaaccauauu caggagcugg cagacaagua ccagggcgcc gguauccccu     2100

uggucagcga cgauuaucug aaagaccacg gcuacaagaa agccuccgaa guguacagug     2160

agauuagcaa ggcagcgucc cucaccaaua cuagcgucac cgccgagaaa agucaauauu     2220

ucaacacuuu uacccugagg gggacguaca ccggcgaaac uuccaagggg gaguucaagg     2280

auugggacga aaugagcaaa aagcucgaug gcacccugga guccuuggcc aaaaauagcu     2340

ggagugguua uaagacucug accgcauacu uuacgaacua ucgcgugacc agcgacaaua     2400

aagugcagua cgauguaguc uuccaugggg ugcucacuga caacgccgau aucuccaaua     2460

acaaggcacc aauugccaag gugaccggcc ccaguacugg cgcggucggg cggaauaucg     2520

aauuuagcgg uaaagacucc aaggaugagg acggcaaaau cgugagcuac gacugggauu     2580

ucggggacgg cgccaccucc agggguaaga acagugugca cgcauauaaa aaggccggga     2640

cguacaaugu aacccugaag gucacugaug acaaaggcgc caccgcaacu gagagcuuua     2700

ccauugaaau caagaacgaa gauacuacca cgccaauuac caaagagaug gagcccaaug     2760

acgauaucaa ggaagccaac ggcccaauug uggagggggu gacugucaaa ggugaccuga     2820

acggcuccga ugacgcggau accuucuauu uugacgugaa ggaagauggg gacguaacua     2880

ucgaguugcc guacaguggc agcuccaauu ucaccuggcu gguguauaaa gagggugacg     2940

aucagaacca caucgccagc gggauugaca agaauaacag uaaggucggc acguucaaau     3000

ccaccaaggg ccgccauuac guguuuaucu auaaacacga uagcgcaucc aauauuagcu     3060

acagucucaa caucaagggg cuggguaaug aaaaacucaa ggagaaggaa aacaaugacu     3120

ccagcgauaa agccacugug auucccaacu ucaauaccac uaugcagggc agucuguugg     3180

gggacgauuc ccgggacuac uauagcuuug aggucaagga agagggcgag gugaacaucg     3240

aacuggauaa aaaggacgag uucgguguaa ccuggacgcu gcauccagaa uccaauauua     3300

acgauaggau caccuacggg caaguggacg gcaauaaagu cagcaacaag gugaagcucc     3360

gccccggcaa auauuaccug uugguguaua aguacagugg gagcgguaac uaugagcugc     3420

gggucaauaa augaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  4460
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt7)

<400>  4460
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucucca      120

gugccuacag cauugcaaac acuaauuccg agaaauauga cuuugaauac uugaacggcc      180

ugaguuauac cgagcucacg aaucugauca agaacauuaa auggaaucag aucaacgggu      240

uguucaauua cagcacuggu ucccaaaagu uuuucggcga uaaaaacagg guccaggcca      300

uuaucaaugc gcugcaggaa agcgggcgga ccuauaccgc caacgacaug aagggcaucg      360

agacuuuuac cgaagugcuc cgcgcagguu ucuaccuggg guauuacaau gauggccugu      420

ccuaccucaa cgacaggaau uuucaggaua agugcauucc cgccaugauc gcaauucaga      480

aaaacccaaa uuucaagcug ggcacggccg uacaggacga ggugaucacu agcuugggga      540

aacugauugg uaacgcgagc gccaacgcag aggucgugaa uaacugugug ccgguccuca      600

agcaguuucg ggaaaaucug aaccaguaug cccccgauua cgugaaaggc accgccguaa      660

augagcugau caaggggauu gaguucgacu ucuccggcgc agccuaugaa aaagauguga      720

agacuaugcc augguacggu aagaucgacc ccuuuaucaa cgaguugaaa gcgcucgggc      780

uguauggcaa uauuaccagc gccaccgaau gggcaaguga ugucggcauc uacuaucugu      840

ccaaguucgg gcucuacagc acgaaccgca augacauugu gcaaucccug gagaaagccg      900

uggauaugua caaguauggu aaaaucgcau uugucgccau ggaaaggauu acuugggacu      960

acgacggcau cgggaguaac ggcaagaagg uggaucacga caaauucuug gaugacgccg     1020

agaagcauua ucugccaaaa accuacacuu uugauaaugg uaccuucauc auucgggcgg     1080

gcgacaaggu aagcgaagag aaaaucaagc gccucuauug ggcauccagg gaggugaaga     1140

gucaguuuca ccgggucgug gggaacgaua aagcccugga agugggcaau gccgacgaug     1200

uccugaccau gaagauuuuc aacagucccg aggaauacaa auuuaauacu aacaucaacg     1260

ggguguccac ggacaauggu ggcuuguaua uugagccacg cgggaccuuc uacacuuacg     1320

aaaggacccc gcagcagagc aucuuuaguc ucgaggagcu guuccggcau gaauauaccc     1380

acuaccugca agcacgcuau cucguagaug gccugugggg ucagggcccc uuuuacgaga     1440

agaacagguu gacuugguuc gacgaaggga cggccgaguu cuuugcgggc uccacccgga     1500

cuagcggggu gcugccacgc aaaagcaucc ucggcuaucu ggccaaggac aaggucgauc     1560

auagguacuc ccugaaaaag accuugaaua gugguuauga cgauagcgac uggauguucu     1620

acaacuacgg guuugcagug gcccacuauc ucuacgaaaa agauaugccc accuucauua     1680

agaugaauaa agcaauccug aacacugacg ucaaguccua ugaugagauu aucaaaaagc     1740

ugagcgacga ugccaauaag aacacggagu accagaauca cauucaagaa cucgccgaca     1800

aauaucaggg cgcagguauc ccacugguga gugaugacua cuugaaggau cauggcuaua     1860

aaaaggccuc cgagguguac agcgaaauuu ccaaagcggc cagucugacc aacacuagcg     1920

uaaccgcaga gaagucccag uacuuuaaua cuuucacccu ccgggggacg uauaccggcg     1980

agacuagcaa gggggaauuu aaagacuggg acgagaugag uaagaaacug gauggcaccc     2040

uggaauccuu ggccaagaac agcugguccg guuacaaaac ucugaccgcc uauuucacga     2100

auuaccgcgu gaccagugac aacaaggucc aguaugaugu ggucuuucac ggggugcuca     2160

cugacaaugc agauaucagc aacaacaagg cgcccaucgc caaagugacc ggcccgucca     2220

cuggcgcagu agggaggaau auugaguuca gcgguaagga caguaaagau gaagacggca     2280

agaucguguc cuacgauugg gacuuugggg auggcgccac cagccggggu aaaaacuccg     2340

uccaugccua caagaaagca gggacguaua augugacccu gaaggucacu gacgacaagg     2400

gcgccaccgc gacugagagc uucaccauug agaucaaaaa cgaagauacg accacuccca     2460

uuaccaagga gauggaacca aaugacgaua ucaaagaggc caacggcccc aucguggaag     2520

gggugacugu aaagggugac cucaauggca gugaugacgc agauaccuuc uacuuugacg     2580

ucaaagagga uggggacgug acuauugagc ugccauauag cggcuccagu aacuucaccu     2640

gguuggugua caaggaaggu gaugaccaaa aucacaucgc cagcgggauu gauaagaaca     2700

auuccaaagu cggcacguuu aagagcacca aaggcaggca cuauguguuc aucuacaagc     2760

augacuccgc caguaacauu agcuauuccc ugaauaucaa agggcucggu aacgagaagc     2820

ugaaggaaaa agagaauaac gacaguagcg auaaggcaac ugugaucccc aacuuuaaua     2880

ccacuaugca gggcucccug uugggggacg auagccgcga cuacuacagu uucgaaguaa     2940

aagaggaggg cgaagucaac auugagcugg auaagaaaga cgaauuuggu gugaccugga     3000

cgcuccaccc agaguccaau aucaacgauc ggauuaccua ugggcaagug gacggcaaua     3060

aggucagcaa caaagugaag cugaggccgg gcaaguacua ucuccuggua uacaaauauu     3120

ccgggagcgg uaauuacgag uugcgcguga acaagugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  4461
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt7)

<400>  4461
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucucca      120

gugccuacag caugaaaaag aacauuuuga aaauccugau ggacuccuau aguaaggaga      180

gcaaaauuca gacugucagg cgggugaccu ccguaagccu ccuggcagug uacuugacga      240

ugaauacuuc cagucugguc cucgccaagc ccaucgaaaa caccaaugau accagcauua      300

agaacgugga gaaacugcgc aaugcgccaa acgaagaaaa uuccaagaaa guggaagaca      360

gcaagaacga uaaagucgag cacgugaaga auaucgagga agccaaagua gagcaagugg      420

caccggaagu caagaguaag uccacucuga ggagcgccuc ccggcgcagg cggaaacgca      480

ucgcaaacac caauagugag aaguaugacu uugaguaccu caacggccug agcuauacgg      540

aauugacuaa ucugauuaaa aacaucaagu ggaaucagau uaacggucuc uucaacuacu      600

ccaccgggag ccagaaauuu uucggcgaua agaauagggu gcaggccauc auuaacgcgc      660

ugcaagagag ugggcggacu uauaccgcca augacaugaa gggcaucgaa accuuuacgg      720

aggugcugcg cgcagguuuc uacuuggggu acuauaacga uggccucucc uaccugaaug      780

acaggaacuu ucaggauaaa ugcauucccg ccaugaucgc cauccagaag aauccaaacu      840

ucaaacuggg cacugcaguc caggacgaag ugauuaccag ccucgggaag cugaucggua      900

augccagugc gaacgccgag guagugaaua acuguguccc cguguugaaa caauuucggg      960

agaaucugaa ccaguaugca ccagauuacg ugaagggcac ugccgucaau gaacucauua     1020

aggggaucga guucgacuuc uccggcgcag ccuaugaaaa agaugugaag accaugcccu     1080

gguacgguaa aauugaccca uuuaucaacg agcugaaggc ccugggguug uauggcaaca     1140

ucaccagcgc gacugaaugg gcaagcgacg uaggcauuua cuaccucucc aaauucgggc     1200

uguauaguac gaaucgcaac gauaucgugc agagccugga gaaggccguc gacauguaca     1260

aguaugguaa aauugccuuu guggcaaugg agaggaucac cugggauuac gacggcauug     1320

gguccaaugg caagaaaguc gaucaugaca aguuccucga ugacgccgaa aaacacuauc     1380

ugccgaagac uuacaccuuu gauaacggua ccuucaucau ccgggcgggc gacaaaguga     1440

gcgaggaaaa gauuaagcgc uuguauuggg ccaguaggga ggugaaaucc caguuucauc     1500

ggguaguggg gaaugauaag gcacuggaag ucggcaacgc cgacgacgug cucacuauga     1560

aaaucuucaa uagccccgag gaguacaagu uuaacacgaa uauuaacggg gucuccaccg     1620

auaauggugg ccuguacauc gaaccacgcg ggacuuucua uaccuacgag aggacucccc     1680

aacagaguau uuuuagccug gaagaguugu uccggcacga guauacccau uaccuccagg     1740

caagguaucu gguggacggc cugugggguc aaggcccauu uuacgagaaa aaccgccuca     1800

cgugguucga ugaggggacc gccgaguucu uugccggcuc cacucggacc agcggggugc     1860

ugcccaggaa gaguaucuug ggcuaucugg caaaggacaa aguagaucac cgcuacuccc     1920

ucaagaaaac ucugaauagc gguuacgacg auuccgacug gauguucuau aacuacgggu     1980

uugccguggc gcacuaucug uacgaaaagg auaugccgac cuucauuaaa augaauaagg     2040

ccaucuugaa cacggacguc aagaguuaug augaaaucau uaaaaagcug agcgacgaug     2100

caaacaaaaa uaccgaguac cagaaccaua uccaggagcu cgccgacaag uaucagggcg     2160

ccgguauucc ccuggugucc gacgauuacc ucaaagacca cggcuacaag aaagcaagcg     2220

aagucuauag ugagaucucc aaggcggcca gccugacuaa uaccuccgug acugcagaaa     2280

agagccaaua cuuuaacacc uucacguugc gggggaccua uacuggcgag accaguaaag     2340

gggaauuuaa ggauugggac gagaugagca aaaagcugga uggcacucuc gagucccugg     2400

ccaaaaauag uuggagcggu uacaagaccc ugacggccua uuucaccaac uacaggguga     2460

cuuccgacaa uaagguacag uacgaugucg uguuucaugg gguguugacc gacaacgcag     2520

auauuagcaa uaacaaagcc ccaaucgcga aggucacugg ccccuccacc ggcgccgugg     2580

ggcgcaauau cgaguucagu gguaaagaca gcaaggauga agacggcaaa auuguguccu     2640

augacuggga uuuuggggac ggcgcaacga gucgggguaa gaacagcgua cacgccuaca     2700

agaaagccgg gaccuauaau gucacucuga aggugaccga ugacaaaggc gcaacugcca     2760

ccgaauccuu cacuaucgag auuaagaacg aagauaccac gaccccaauc acuaaagaga     2820

uggagcccaa ugacgauauu aaggaagcga acggcccaau cguggagggg gucaccguga     2880

aaggugaccu caacggcagc gaugacgccg auacuuucua cuuugacgua aaggaagaug     2940

gggacgugac caucgagcug ccguauagug gcuccagcaa uuucacgugg cucgucuaca     3000

aggaggguga cgaucagaac cacauugcau ccgggaucga caaaaauaac agcaaggugg     3060

gcaccuuuaa aaguacuaag ggcaggcauu auguguucau uuacaaacac gauuccgcca     3120

gcaauaucag uuacucccug aacauuaagg gguuggguaa ugaaaagcug aaagagaagg     3180

aaaacaauga cagcuccgau aaagcaaccg ucauccccaa cuuuaauacu accaugcagg     3240

gcagccugcu cggggacgau agucgggacu auuacagcuu cgaggugaag gaagagggcg     3300

agguaaacau ugaacuggau aaaaaggacg aguuuggugu gacguggacc uugcauccag     3360

aauccaauau caacgaucgc aucacuuaug ggcaagucga cggcaauaag gugaguaaca     3420

aagugaagcu gaggcccggc aaauacuauc uccuggucua caaguauagc ggguccggua     3480

acuacgagcu ccgggugaau aaaugaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  4462
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt7)

<400>  4462
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuga agaucauucu caauaggggc aaaaccauga      120

agcggaaaug ccugagcaag cgcuugaugc uggccaucac uauggcaacc auuuuuacgg      180

ugaacuccac ucuccccauc uacgccgcgg ucgacaaaaa uaacgccacc gcagccgugc      240

agaaugagag uaagagguau accguaagcu accugaagac uuugaacuau uacgaucugg      300

uggaccuccu ggucaaaacc gaaauugaga aucugccaga ucucuuccaa uauuccagug      360

acgcaaagga auuuuacggg aacaaaacgc ggaugagcuu caucauggau gagaucgguc      420

gcagggcccc gcaguauacu gaaauugacc acaagggcau ccccacccug guggaggugg      480

uccgggcggg guuuuacuug ggcuuccaua auaaagagcu gaacgaaauu aauaagcgcu      540

ccuuuaaaga gagggugauc ccaagcauuc ucgccaucca gaagaacccc aauuucaagc      600

uggguacuga aguacaggau aaaauugugu ccgcaaccgg gcuguuggcc ggcaacgaga      660

ccgccccacc cgaggucgug aauaacuuua cgccaauccu ccaagacugu aucaagaaca      720

uugaucggua cgcacuggac gaucugaaaa guaaggcccu cuucaaugug cuggcggccc      780

cgacuuauga caucaccgaa uacuugcgcg caacuaaaga gaagcccgaa aacaccccau      840

gguauggcaa gauugauggg uuuaucaaug agcugaaaaa gcucgcccug uacgguaaaa      900

uuaacgacaa uaacagcugg aucaucgaca auggcauuua ucacaucgca ccccugggga      960

aguugcauuc caacaauaaa auuggcaucg aaacccucac ugaggucaug aagguguacc     1020

cauaucugag caugcagcau cugcagagug ccgaucagau uaagaggcac uacgacucca     1080

aagaugccga ggguaacaag aucccccucg acaaauucaa gaaagaaggg aaggagaagu     1140

acugcccgaa aacguauacc uucgaugacg gcaagguaau cauuaaagcg ggcgcacggg     1200

uggaagagga aaaggucaaa cgccuguacu gggccagcaa ggaggugaau agucaauuuu     1260

ucagggugua ugggaucgau aaacccuugg aggaagguaa cccagacgau auucugacua     1320

uggucaucua caauaguccc gaggaauaua agcucaacag cgugcuguac ggcuaugaca     1380

ccaauaacgg gggcauguac auugagccag aagguaccuu uuucacuuac gagcgggagg     1440

cccaggaauc cacguauacc cuggaggaau uguuucgcca cgaguacacu cacuaucucc     1500

agggcaggua cgcaguaccc gggcaguggg gccggaccaa gcuguaugau aacgaccgcc     1560

ugaccuggua cgaggaaggg ggugccgaac ucuucgcggg cagcacuagg acgaguggga     1620

uccugccacg gaaauccauu gugagcaaua uccauaacac cacuaggaau aaccgcuaua     1680

aguugaguga caccguccac uccaaauacg gcgccagcuu ugaguucuac aauuaugcau     1740

guauguuuau ggauuacaug uauaacaagg acauggguau ccugaauaaa cucaacgauc     1800

uggccaagaa uaacgacgug gauggcuacg acaauuauau ucgggaucug agcuccaacu     1860

acgcauugaa ugacaaguau caagaucaua ugcaggagag gaucgacaac uacgaaaauc     1920

ugacuguccc guucguggcc gaugacuacc ucgugcgcca cgccuauaaa aaccccaacg     1980

agauuuacag ugagaucagc gaaguagcaa agcugaaaga ugccaagucc gaggugaaaa     2040

agagccagua uuuuaguacc uucacgcucc ggggguccua caccggcggg gcgagcaagg     2100

gcaaacugga agaccaaaag gccaugaaua aauuuauuga cgauuccuug aagaaacugg     2160

acacuuauag uuggagcggu uacaagaccc ucacugcaua cuucaccaac uauaaagucg     2220

auuccagcaa uagggugacg uacgacgucg uguuccacgg guaucugcca aacgagggcg     2280

auaguaaaaa uucccugccc uacgguaaga ucaacggcac cuauaagggg acugaaaagg     2340

agaaaaucaa guuuagcucc gagggcaguu ucgacccaga ugggaaaauu gugagcuacg     2400

aaugggacuu uggcgauggu aauaagucca acgaggaaaa ucccgagcau agcuaugaca     2460

agguagggac cuacacugug aaauugaagg ucaccgauga caaaggcgaa aguuccguga     2520

gcacgaccac ugccgagauc aaggaccugu ccgagaacaa acucccgguc auuuacaugc     2580

acgugccaaa gagcggcgcc cugaaucaga aggugguauu cuaugggaaa gguaccuacg     2640

aucccgacgg caguaucgca ggguaucagu gggauuuugg cgacgguagc gauuucucca     2700

gugaacagaa ccccagccau gucuacacua agaaagggga guauaccgug acgcuccgcg     2760

ugauggacuc cagcggccaa auguccgaaa agaccaugaa aauuaagauc acugauccag     2820

ucuaccccau cggcaccgag aaagagccaa auaacaguaa ggaaacugcg agcgggccga     2880

uugugcccgg uaucccagug uccggcacca uugagaauac uuccgaccag gauuauuuuu     2940

acuucgacgu aaucaccccc ggggaaguca agauugauau caacaaacug ggcuacggug     3000

gggccacgug ggugguguau gacgagaaca auaacgcagu cagcuacgcc accgaugacg     3060

gccagaauuu guccggcaag uuuaaagccg acaagccagg gcgguauuac auucaccugu     3120

auauguucaa cgguagcuac augcccuaua ggaucaauau cgaaggcagu guggggcggu     3180

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  4463
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt7)

<400>  4463
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaggaaau gccugagcaa gcggcucaug cuggccauca      120

ccauggcaac uauuuucacc gugaacucca cguugcccau cuacgccgcg gucgacaaaa      180

auaacgccac ugcagccgug cagaaugaga guaagcgcua uaccguaagc uaccugaaaa      240

cccucaacua uuacgaucug guggacuugc uggucaagac ugaaauugag aaucucccag      300

aucuguuuca auauuccagu gacgcaaagg aguucuacgg caacaaaacc aggaugagcu      360

uuaucaugga ugaaauuggg cggcgcgccc cgcaguauac ggaaaucgac cacaagggua      420

uccccacucu gguggaggug gucagggcgg gcuucuaccu cggguuucau aauaaagagc      480

ugaacgaaau uaauaagcgg uccuucaaag agcgcgugau cccaagcauu uuggccaucc      540

agaagaaccc caauuuuaaa cugggcaccg aaguacagga uaagauugug uccgcaacug      600

gucuccuggc cgggaacgag accgccccac ccgaggucgu gaauaacuuc accccaaucc      660

ugcaagacug uauuaagaau aucgauaggu acgcauugga cgaucucaaa aguaaggccc      720

uguuuaacgu gcuggcggcc ccgacguaug acaucacuga auaccuccgg gcaaccaaag      780

agaagcccga aaacacucca ugguauggca aaauugaugg cuucaucaau gagcugaaga      840

aguuggcccu guacgggaaa auuaacgaca auaacagcug gaucauugac aaugguaucu      900

aucacaucgc accccucggc aagcugcauu ccaacaauaa aauugggauc gaaacccuga      960

ccgaggucau gaagguguac ccauauuuga gcaugcagca ccuccagagu gccgaucaga     1020

uuaaacgcca uuacgacucc aaggaugccg agggcaacaa gaucccccug gacaaauuua     1080

agaaagaagg uaaggagaaa uacugcccga agacuuauac guucgaugac gggaagguaa     1140

uuaucaaagc gggcgcaagg guggaagagg aaaaggucaa acggcuguac ugggccagca     1200

aggaggugaa uagucaauuc uuucgcgugu auggcaucga uaaaccccuc gaggaaggga     1260

acccagacga uauucugacc auggucaucu acaauagucc cgaggaauau aaguugaaca     1320

gcgugcugua cgguuaugac acuaauaacg gcgggaugua cauugagcca gaaggcaccu     1380

ucuuuaccua cgagagggag gcccaggaau ccacuuauac gcucgaggaa cuguuccggc     1440

acgaguacac ccacuaucug cagggucgcu acgcaguacc cggccagugg gggaggacua     1500

aauuguauga uaaugaccgg cucaccuggu acgaggaagg cggggccgag cuguuugcgg     1560

guagcacccg cacuuccggc auccugccaa ggaaguccau ugugagcaac auccauaaca     1620

cgacccggaa uaacagguau aagcucagug acacugucca cuccaaauac ggggccagcu     1680

ucgaauuuua caauuaugca uguauguuca uggauuacau guauaacaag gacaugggca     1740

uucugaauaa auugaacgau cuggccaaga auaacgacgu ggaugguuac gacaauuaua     1800

uccgcgaucu cagcuccaac uacgcacuga augacaaaua ucaagaucau augcaggagc     1860

ggaucgacaa cuacgaaaau cugaccgucc cguuuguggc cgaugacuac uuggugaggc     1920

acgccuauaa gaaccccaau gagauuuaca gugagaucag cgaaguagca aagcugaaag     1980

augccaaguc cgaggugaaa aagagccagu auuucaguac uuuuacccuc cgcggcuccu     2040

acacgggcgg cgcgagcaaa gggaagcugg aagaccaaaa ggccaugaac aaauucauug     2100

acgauucccu caagaaacug gacaccuaua guuggagcgg cuacaagacu uugaccgcau     2160

acuuuacuaa cuauaaaguc gauuccagca aucgggugac cuacgacguc guguuccacg     2220

guuaucugcc aaacgagggg gauaguaaaa auucccuccc cuacggcaag aucaacggua     2280

cguauaaggg caccgaaaag gagaaaauua aguucagcuc cgaggggagu uuugacccag     2340

auggcaaaau cgugagcuac gaaugggacu ucggggaugg caauaagucc aacgaggaaa     2400

aucccgagca uagcuaugac aaaguaggua cuuacaccgu gaagcugaag gucacugaug     2460

acaaagggga aaguuccgug agcaccacga ccgccgagau caaggaccug uccgagaaca     2520

aauugccggu cauuuacaug cacgugccaa agagcggcgc ccugaaucag aaagugguau     2580

uuuauggcaa ggggacuuac gaucccgacg guaguaucgc aggcuaucag ugggauuucg     2640

gggacggcag cgauuuuucc agugaacaga accccagcca ugucuacacc aagaaaggug     2700

aguauacugu gacccucagg gugauggacu ccagcgggca aauguccgaa aagacgauga     2760

aaauuaagau caccgaucca gucuacccca uuggcacuga gaaagagcca aauaacagua     2820

aggaaaccgc gagcggcccg aucgugcccg ggaucccagu guccgguacu auugagaaua     2880

ccagugacca ggauuauuuc uacuuugacg uaaucacucc cggcgaaguc aaaauugaua     2940

ucaacaagcu gggguacggc ggugccaccu ggguggugua ugacgagaau aacaacgcag     3000

ucagcuacgc cacggaugac gggcagaauc ucuccggcaa guucaaagcc gacaagccag     3060

gccgcuauua cauucaccug uauauguuua acgggagcua caugcccuau cggaucaaua     3120

uugaagguag uguggggagg ugaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  4464
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt7)

<400>  4464
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucucca      120

gugccuacag cguccagaac gaguccaaaa gguauacugu gaguuacuug aagacccuga      180

auuauuacga ccucguagau cuguugguga aaacggaaau ugagaaccug cccgaccucu      240

uucaauauag cuccgaugca aaggaguucu acggcaauaa aacucggaug agcuuuauca      300

uggacgaaau ugggcgcagg gccccacagu auaccgaaau cgaucacaag gguauuccga      360

cccuggucga gguggugcgg gcgggcuucu accugggguu ucauaacaag gagcucaaug      420

aaaucaacaa acgcuccuuc aaggagaggg ucauccccag uauucuggcc auccagaaaa      480

auccaaacuu uaaguugggc acugaagugc aggacaaaau uguaagcgca accggucugc      540

ucgccgggaa ugagacggca cccccagagg uggucaacaa uuucacuccc auccugcaag      600

auugcauuaa gaacaucgac cgguacgccc uggaugacuu gaaauccaag gcgcucuuua      660

augugcuggc cgcaccaacc uaugauauua cugaauaccu gcgcgccacc aaggagaaac      720

cggaaaacac ccccugguau ggcaagaucg acggcuucau caaugagcuc aaaaagcugg      780

ccuuguacgg gaaaauuaac gauaacaaua gcuggaucau ugacaacggu aucuaucaca      840

uugcaccacu gggcaagcuc cauaguaaua acaagaucgg gaucgaaacg cugacugagg      900

ugaugaaagu cuaccccuau cuguccaugc agcacuugca gagcgccgac cagauuaaga      960

ggcauuacga uuccaaagac gcggagggca auaagauccc acucgauaaa uucaagaagg     1020

aagguaaaga gaaguacugu cccaaaaccu auacuuuuga cgaugggaag gugauuauca     1080

aagccggcgc acggguagaa gaggaaaagg ugaagcgccu guacugggcc aguaaagagg     1140

ucaacagcca auucuuuagg guguauggca uugacaagcc gcuggaggaa gggaaucccg     1200

augacauccu caccauggug aucuacaacu ccccagagga auauaaacug aauagcgucu     1260

uguacgguua ugauaccaac aauggcggga uguacauuga gcccgaaggc acuuucuuua     1320

cguacgagcg ggaggcacag gaaaguaccu auacucugga ggaacucuuc cgccacgagu     1380

acacccacua ucugcagggu agguacgccg ugccaggcca gugggggcgg accaagcugu     1440

augacaacga ucgcuugacu ugguacgagg aaggcggggc cgagcucuuu gcggguucca     1500

cgaggaccag cggcauccug ccccggaaaa guauuguauc caauauccau aacacuaccc     1560

gcaauaacag guauaagcug agcgacaccg ugcacagcaa auacggggca uccuucgaau     1620

uuuacaacua ugccugcaug uucauggacu acauguauaa uaaggauaug ggcauucuca     1680

acaagcugaa ugacuuggcc aaaaacaaug augucgacgg uuacgauaac uauauccggg     1740

accugaguag caauuacgca cucaacgaua aguaucaaga ccauaugcag gagaggauug     1800

auaauuacga aaaccugacu gugccauuug ucgccgacga uuaccuggug cgccacgcgu     1860

auaaaaaucc gaacgagauc uacuccgaga ucagcgaagu ggccaaguug aaagacgcaa     1920

agagugaggu aaagaaaucc caguauuuca gcacguuuac ccugcggggc uccuacacug     1980

ggggcgccag uaaggggaaa cucgaagauc aaaaggcaau gaauaaauuc auugacgaca     2040

gccugaagaa gcucgauacc uauuccugga gcggcuacaa aacucugacc gccuacuuca     2100

cgaacuauaa gguggacagu uccaauaggg ucaccuacga uguggucuuu cacgguuauu     2160

ugcccaacga gggggacagc aaaaacuccc ugccauacgg caagaucaau gguacuuaua     2220

aaggcaccga aaaggagaaa auuaaguuca guagcgaggg guccuuugau cccgacggca     2280

agaucgugag cuacgaaugg gauuucgggg acggcaacaa aaguaaugag gaaaacccag     2340

agcauuccua ugauaaggug gguacuuaca ccguaaaacu caaggugacg gacgauaaag     2400

gggaaagcuc cgucagcacc acuaccgccg agauuaagga ccugagugag aauaagcugc     2460

ccgugaucua caugcacguc ccgaaaagcg gcgcauugaa ccagaaggug guguuuuaug     2520

gcaaagggac uuacgaccca gaugguucca ucgccggcua ucagugggac uucggggaug     2580

gcagugacuu uagcuccgaa cagaauccca gccauguaua caccaagaaa ggugaguaua     2640

cggucacccu gcgcgugaug gauuccagug ggcaaaugag cgaaaagacu augaagauua     2700

aaaucaccga ccccguguac ccaauuggca cugagaagga gcccaacaau uccaaagaaa     2760

ccgcgagugg cccaaucguc ccggggauuc ccgugagcgg uacgaucgag aacaccuccg     2820

aucaggacua uuucuacuuu gaugugauca cuccaggcga aguaaagauu gacaucaaua     2880

aacucgggua cggcggugcc accugggucg uguaugauga gaacaauaac gcagugagcu     2940

acgccacuga cgaugggcag aaucugagug gcaaguucaa agccgacaag cccggccggu     3000

auuacauuca ccucuauaug uuuaacgggu ccuacaugcc auauaggauc aacauugaag     3060

guagcgucgg ccgcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4465
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt7)

<400>  4465
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucucca      120

gugccuacag caugaaaagg aagugcuugu ccaaacggcu gaugcucgca auuacuaugg      180

ccaccaucuu uacggucaac aguacucugc ccauuuaugc ggccguggac aagaauaacg      240

caaccgccgc acgcaggcgg cgcaaaaggg uacagaauga gagcaagcgg uacaccgugu      300

ccuauuugaa gacucugaac uacuaugauc ucgucgaccu gcuggugaaa accgaaaucg      360

agaaucuccc agaucuguuc caauacagcu ccgacgccaa ggaauuuuau ggcaacaaaa      420

cgcgcaugag uuucauuaug gaugagaucg ggaggcgggc gccgcaguac acugaaaucg      480

accacaaggg uauucccacc uugguggagg ucgugcgcgc cggcuuuuac cugggguucc      540

auaauaaaga gcucaacgaa aucaauaaga ggagcuuuaa agagcgggua auuccaucca      600

uccuggcaau ucagaagaac cccaauuuca agcugggcac ugaagugcag gauaaaaucg      660

ucagcgccac cgguuugcuc gccgggaacg agaccgcacc acccgaggug gugaauaacu      720

uuacgccaau ucugcaagac uguaucaaga auaucgaucg cuaugcccug gacgaucuca      780

aaaguaaggc gcuguucaac gucuuggccg caccgacuua cgacauuacc gaauaucuga      840

gggccacuaa agagaagccc gaaaacaccc caugguacgg caagaucgau ggcuucauua      900

augagcucaa aaagcuggca cuguauggga aaaucaacga caauaacucc uggauuaucg      960

acaaugguau cuaccacauu gcccccuugg gcaagcucca uagcaacaau aaaaucggga     1020

uugaaacccu gacugaggug augaagguau auccauaccu guccaugcag caccuccaga     1080

gugccgauca gaucaagcgg cauuacgaca gcaaagaugc ggagggcaac aagauucccc     1140

uggacaaauu uaagaaagaa gguaaggaga aguauugccc gaaaacguac accuucgaug     1200

acgggaaggu gaucaucaaa gcaggcgccc gcgucgaaga ggaaaaggug aaaagguugu     1260

auugggccuc caaggaggug aauagccaau uuuuccgggu cuacggcauu gauaaacccc     1320

uggaggaagg gaacccagac gauauccuca cuauggugau uuauaauagu cccgaggaau     1380

acaagcugaa cuccguacug uaugguuacg acaccaauaa cggcgggaug uacaucgagc     1440

cagaaggcac cuuuuucacu uaugagcgcg aggcacagga aagcacguac accuuggagg     1500

aacucuuuag gcacgaguau acucacuacc ugcagggucg guaugccgug cccggccagu     1560

gggggaggac caagcuguac gauaaugacc gccucaccug guaugaggaa ggcggggcgg     1620

agcuguucgc cgguaguacu cggacguccg gcauuuugcc aaggaaaagc aucgucagca     1680

acauucauaa caccacucgc aauaaccggu acaagcuguc cgacaccgug cacaguaaau     1740

acggggcgag cuuugaguuc uauaauuacg ccuguauguu uauggauuau auguacaaca     1800

aggacauggg cauccucaau aaacugaacg aucuggcaaa gaauaacgac gucgaugguu     1860

augacaauua caucagggau uuguccagca acuaugcccu gaaugacaag uaccaagauc     1920

auaugcagga acgcauugac aacuacgaaa aucucacugu gccguucgug gccgaugacu     1980

aucugguacg gcacgcauac aaaaacccca augagaucua uagugagauu uccgaagugg     2040

ccaagcucaa agaugcaaag agcgagguca aaaaguccca guacuuuagu accuucacgc     2100

ugaggggcag cuauaccggg ggcgccucca aggggaaauu ggaagaccaa aaggcaauga     2160

acaaauucau cgacgauagc cugaagaaac ucgacacuua caguuggucc ggcuacaaga     2220

cccugacugc cuauuuuacc aacuacaaag uggauagcuc caaucggguc acguaugacg     2280

ugguguucca cgguuaccug ccaaacgagg gggauaguaa gaauagcuug cccuauggca     2340

agauuaacgg uaccuacaaa ggcacugaaa aggagaaaau caaguuuucc agcgagggga     2400

guuucgaccc agauggcaaa aucguauccu augaauggga cuuuggggau ggcaauaaga     2460

gcaacgagga aaaucccgag cauuccuacg acaagguggg uaccuacacu gucaaacuga     2520

aggugaccga ugacaaaggg gaaagcagug ucagcacgac cacugccgag auuaaggacc     2580

ucuccgagaa caaacugccg gugaucuaua ugcacgugcc aaagaguggc gcacucaauc     2640

agaagguagu cuucuacggc aaagggaccu augaucccga cgguagcauu gcgggcuacc     2700

agugggauuu uggggacggc uccgauuuca gcuccgaaca gaaccccagu cauguguaua     2760

cuaagaaagg ugaguacacc gugacgcugc gcgucaugga cagcuccggg caaaugagug     2820

aaaagaccau gaaaaucaag auuacugauc caguguaucc caucggcacc gagaaagagc     2880

caaauaacag caaggaaacu gccuccggcc cgaucgugcc cgggauucca guaagcggua     2940

ccaucgagaa uaccagugac caggauuacu uuuacuucga cgucauuacu cccggcgaag     3000

ugaagaucga uauuaacaaa uugggguaug gcggugcaac gugggugguc uacgacgaga     3060

auaacaacgc cguguccuau gccaccgaug acgggcagaa ucugagcggc aaguuuaaag     3120

cagacaagcc aggcagguac uauauccacc uguacauguu caacgggucc uauaugcccu     3180

accggauuaa uaucgaaggu agcguaggcc gcugaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  4466
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt7)

<400>  4466
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcagccu      120

uugcgaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc agcuaugagg      180

ugcugacucc ccucaagugg uaccagucca ucaggccacc cuauccaagu uacggguaug      240

aaccgauggg cgguuggcug caccaucaaa uuauccccgu cuugagccag cagcacccac      300

ccacccauac gcugcagcca caccaccaua uucccguggu accggcccaa cagcccguga      360

ucccacagca gcccaugaug ccaguccccg ggcaacacuc caugacucca auccagcauc      420

accagccgaa ucugccccca cccgcacagc aaccauacca gccccagccg gugcaaccac      480

agccccacca gcccaugcag ccacaacccc cagugcaucc gaugcagccc cucccacccc      540

agccaccccu gccgccaaug uuucccaugc agccacugcc cccgaugcuc cccgacuuga      600

cccuggaggc cuggccaagu accgauaaaa cuaagcggga agaggucgac ugaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  4467
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt7)

<400>  4467
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacc ccacugaagu gguaccaguc cauuaggcca cccuauccca      180

guuacgguua ugaaccgaug ggcggguggu gaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  4468
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt7)

<400>  4468
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacu ccccugaagu gguaccaguc cauuaggcca cccccaaugu      180

ugccggaccu gacccucgaa gccuggccca guaccgauaa aacgaagcgg gaggaagucg      240

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  4469
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt7)

<400>  4469
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cacccaggac ccugguccuc cuguugagcg      120

gcgcccuggc gcucacucag accugggcca ugccacugcc gccccaccca gggcaucccg      180

guuacaucaa cuucuccuau gagguguuga cgccacugaa gugguaccaa aguauucggc      240

ccccauaucc gagcuacggc uaugaaccca ugggcgggug gugaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  4470
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt7)

<400>  4470
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cacccaggac ccugguccuc cuguugagcg      120

gcgcccuggc gcucacucag accugggcca ugccacugcc gccccaccca gggcaucccg      180

guuacaucaa cuucuccuau gagguguuga cgccacugaa gugguaccaa aguauucggc      240

ccccaccgau gcuccccgac cugacucugg aagcauggcc aagcaccgau aaaaccaagc      300

gcgaggaagu agacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  4471
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt7)

<400>  4471
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccucgug ggggcagccu      120

uugcgaugcc ccugccaccg caccccgguc auccaggcua cauuaacuuc agcuaugagg      180

ucuugacucc ccugaagugg uaccagucca ugaucaggcc acccuauagu agcuacgggu      240

augaaccaau gggcgguugg cuccaccauc aaauuauccc ggugguaucc cagcagcacc      300

cccugaccca uacguugcag agucaccacc auauuccagu gguccccgcc caacagccac      360

gggugcgcca gcaggcacug augcccgugc cggggcaaca gagcaugacu cccacccagc      420

accaucagcc aaaucucccc cugccagccc aacagcccuu ucagccacaa ccgguccagc      480

cccagccaca ccagcccaug caaccacagc ccccggugca gccaaugcag ccccugcucc      540

cccaaccacc ccugccaccg auguuccccu ugaggccacu gcccccaauc cuccccgacc      600

ugcaccugga ggcauggccg gccaccgaua aaacuaagca ggaagaggua gacugaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  4472
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt7)

<400>  4472
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacc ccacugaagu gguaccaguc caugauuagg ccacccuaua      180

guagcuacgg uuaugaaccc augggcgggu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4473
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt7)

<400>  4473
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacu ccccugaagu gguaccaguc caugauuagg ccacccccaa      180

ucuugccgga ccugcaccuc gaagccuggc ccgcaaccga uaaaaccaag caagaggaag      240

ucgacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4474
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt7)

<400>  4474
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cacccaggac ccugguccuc cuguugagcg      120

gcgcccuggc gcucacucag accugggcca ugccacugcc gccccaccca gggcaucccg      180

guuacaucaa cuucuccuau gagguguuga cgccacugaa gugguaccaa aguaugauuc      240

ggcccccaua uagcuccuac ggcuaugaac cgaugggcgg guggugagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4475
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt7)

<400>  4475
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cacccaggac ccugguccuc cuguugagcg      120

gcgcccuggc gcucacucag accugggcca ugccacugcc gccccaccca gggcaucccg      180

guuacaucaa cuucuccuau gagguguuga cgccacugaa gugguaccaa aguaugauuc      240

ggcccccacc gauccucccc gaccugcacc uggaagcaug gccagccacu gauaaaacca      300

agcaggagga aguagacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4476
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt7)

<400>  4476
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcagccu      120

uuagcaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc uccuaugagg      180

ugcugacucc ccucaagugg uaccagaaua ugaucaggca cccauauacc aguuacgggu      240

augaacccau gggcgguugg cugcaucacc aaauuauccc agucgugagc cagcagacgc      300

cgcaguccca ugcguugcaa ccccaccacc auauuccaau gguacccgcc cagcagccag      360

ggauccccca gcaaccgaug augccccugc caggccagca caguaugacu cccacccagc      420

aucaccagcc aaaccucccc cugccagcac aacagccguu ucagccccaa ccagugcagc      480

cccagccaca ccagccccug caaccgcaga gcccaaugca ucccauccag ccccuccugc      540

cacagccccc auugccgccc auguucucca ugcaaagccu gcucccagac cugccccugg      600

aggccuggcc agcaaccgau aaaacuaagc gggaagaggu cgacugagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4477
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt7)

<400>  4477
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacu ccccugaagu gguaccagaa uaugauuagg cacccauaua      180

ccuccuacgg uuaugaaccc augggcgggu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4478
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt7)

<400>  4478
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacu ccccugaagu gguaccagaa uaugauuagg cacccauccu      180

ugcugcccga ccucccacug gaagccuggc cggcaaccga uaaaaccaag cgggaggaag      240

ucgacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4479
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt7)

<400>  4479
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cacccaggac ucugguccuc cuguugagcg      120

gcgcccuggc gcucacucag accugggcca ugccacugcc gccccaccca gggcaucccg      180

guuacaucaa cuucuccuau gagguguuga cgccacugaa gugguaccaa aauaugauuc      240

ggcaccccua uaccaguuac ggcuaugaac caaugggcgg guggugagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4480
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt7)

<400>  4480
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cacccaggac ccugguccuc cuguugagcg      120

gcgcccuggc gcucacucag accugggcca ugccacugcc gccccaccca gggcaucccg      180

guuacaucaa cuucuccuau gagguguuga cgccacugaa gugguaccaa aauaugauuc      240

ggcaccccag ucuccugcca gaccugccgc ucgaagcaug gcccgccacu gauaaaacca      300

agcgcgagga aguagacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4481
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt7)

<400>  4481
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcagccu      120

uuagcaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc uccuauauca      180

ggcaccccua caccaguuau ggguacgagc caaugggcgg uuggcugcau caccagauua      240

uccccguggu cagccaacag acuccacagu cccaugcgcu ccagccgcac caccauauuc      300

ccauggugcc agcccaacag cccgggaucc cacagcagcc caugaugccg cugcccggcc      360

aacacaguau gacgccaacu cagcaucacc agcccaauuu gccacugccc gcacagcaac      420

cauuucagcc gcagcccgua caaccacagc cccaccagcc acuccagccc caaagcccga      480

ugcauccaau ccagccccug cugccccagc caccccuccc accgauguuc uccaugcaga      540

gccuguugcc cgaccugcca cucgaagccu ggcccgcaac cgauaagacc aaacgggagg      600

aaguggacug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  4482
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt7)

<400>  4482
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuuugc cugccugcuc ggggcaagcc      120

uggccaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc uccuaugagg      180

ugcugacucc ccucaagugg uaccagaaua ugaucaggca cccauauacc aguuacgggu      240

augaacccau gggcgguugg cugcaucacc aaauuauccc agucgugagc cagcagacgc      300

cgcaguccca ugcguugcaa ccccaccacc auauuccaau gguacccgcc cagcagccag      360

ggauccccca gcaaccgaug augccccugc caggccagca caguaugacu cccacccagc      420

aucaccagcc aaaccucccc cugccagcac aacagccguu ucagccccaa ccagugcagc      480

cccagccaca ccagccccug caaccgcaga gcccaaugca ucccauccag ccccuccugc      540

cacagccccc auugccgccc auguucucca ugcaaagccu gcucccagac cugccccugg      600

aggccuggcc agcaaccgau aaaacuaagc gggaagaggu cgacugagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4483
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt7)

<400>  4483
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcagccu      120

uuagcaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc uccuaugagg      180

ugcugacucc ccucaagugg uaccagaaua ugaucaggca cccaagucug uugcccgacc      240

ugccacucga agcguggccg gccaccgaua aaacgaagcg ggaggaaguc gacugaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  4484
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt7)

<400>  4484
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcagccu      120

uuagcaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc uccuaugagg      180

accuguaccu cgaagcgauc aggauugauc ggacugccuu ugugcugacc cccuugaagu      240

gguaucagaa uaugauccgc cacccauaca cgaguuaugg guacgagccc augggcgguu      300

ggcugcauca ccaaauuauc ccagucguga gccagcagac uccgcagucc caugcacucc      360

aaccccacca ccauauccca augguacccg cccagcagcc agggauuccc cagcaaccga      420

ugaugccccu gccaggccag cacaguauga cccccaccca gcaucaccag ccaaaccugc      480

cccucccagc acaacagccg uuccagcccc aaccagugca gccccagcca caccagcccc      540

ugcaaccgca gagcccaaug caucccaucc agcccuugcu gccacagccc ccacucccgc      600

ccauguuuuc caugcaaagc cugcugccag acuugccccu cgaagccugg ccagcgacug      660

auaaaaccaa gagggaggaa gucgacugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  4485
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt7)

<400>  4485
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcagccu      120

uuagcaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc uccuaugagg      180

ugcugacucc ccucaagugg uaccagaaua ugaucaggca cccaacgccc caaagucaug      240

cgcugcagcc acaccaucac auuccgaugg uccccgccca gcagccaggg aucccccaac      300

agccaaugau gcccuugccg ggccagcaca gcaugacccc cacucagcau caccaaccaa      360

accugccccu cccagcacag cagcccuuuc agccacaacc ggugcagccc cagccacauc      420

aaccccugca gccacagucc cccaugcacc cgauucagcc acugcucccc caacccccac      480

ugcccccaau guucaguaug cagagcuugc ugccggaccu cccccuggaa gccuggccag      540

caaccgauaa aaccaagcgg gaggaaguag acugaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  4486
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt7)

<400>  4486
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacu ccccugaagu gguaccagaa uaugauuagg cacccauaua      180

ccuccuacgg uuaugaaccc augggcgggu gguugcauca ccaaaucauu ccagucguga      240

gucagcagac cccgcagagc caugcccugc aaccccacca ccauauccca augguacccg      300

cacagcagcc aggcauuccc cagcaaccga ugaugccccu cccaggucag cacuccauga      360

cgcccacuca gcaucaccag ccaaaccugc ccuugccagc ccaacagccg uuucagcccc      420

aaccagugca gccccagcca caccagcccc ugcaaccgca gaguccaaug caucccaucc      480

agccccuccu gccacagccc ccacugccgc ccauguucag caugcaaucc cuccugccag      540

acuugccccu ggaggcgugg ccagccaccg auaaaaccaa gcgggaagag gucgacugag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  4487
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt7)

<400>  4487
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg ccaggcugcc acuccuguug gggcugcucc      120

uguugccgcg gcccggucgc ccacuggacc ucgcagauua caccuaugac cuggccgagg      180

aagaugacag cgagccccug aacuacaagg auccaugcaa agcggccgca uuccucggcg      240

acaucgcccu ggaugaagag gacuugaggg cauuucaggu ccaacaggcc guggaucugc      300

ggcgccacac ugcgaggaag uccaguauua aagccgcagu acccgggaau accagcacgc      360

cauccuguca gaguacuaac ggccagccgc aacggggugc cugcgggcgc uggaggggcc      420

ggagccgcuc caggcgggcc gcaaccagcc gccccgaaag gguguggcca gacggcguca      480

uccccuucgu gauugggggu aauuuuaccg gcucccagcg ggccguguuc cgccaggcga      540

ugaggcauug ggagaagcac acuuguguca ccuuucucga gcggacggau gaagacaguu      600

auaucguguu cacuuaccgc ccaugcgggu guugcagcua uguaggcagg cggggugggg      660

gcccccaggc cauuuccauc ggcaaaaacu gugauaaguu ugggaucgug guccaugagc      720

ugggucacgu ggugggcuuc uggcaugaac acaccaggcc ggaccgcgac cggcacguca      780

gcauugugag ggagaauauc caacccgggc aggaguacaa cuuucugaag auggaaccac      840

aggagguaga aaguuugggc gagacuuaug auuucgacuc cauuaugcau uacgcacgca      900

auaccuuuag ccgggguauc uuccucgaua ccauugugcc caaauacgaa gucaacggcg      960

ugaagccacc caucgggcag aggacgcgcc uguccaaagg cgacauugcc caagcacgga     1020

agcuguauaa augcccagcc uguggggaga cucuccagga uaguaccggu aauuucagcu     1080

ccccggagua ccccaacggc uauagcgccc acaugcauug cguguggagg aucaguguca     1140

cuccagggga aaagaucauu cugaauuuua ccuccuugga ccuguaccgg agccgccucu     1200

gcugguauga uuacguggag guaagggacg gcuucuggcg gaaagcgccc cugcgcggua     1260

gguuuugugg caguaagcug ccagaaccca ucguguccac cgauagccgg uugugggucg     1320

aguuccgcag cuccaguaac ugggugggga agggcuuuuu cgcagucuau gaagccauuu     1380

gcgggggcga cgugaaaaag gauuacgguc acauccagag cccgaauuac ccagacgacu     1440

auaggcccuc caaagugugu auuuggcgga uccaaguaag cgagggguuu cacgugggcc     1500

ucacuuucca gaguuuugag aucgaaaggc augauuccug cgccuacgac uaucuggagg     1560

uccgcgaugg ucacagcgaa uccaguacgc ugauuggccg guacuguggg uaugagaagc     1620

ccgacgauau caaaagcacc uccagcaggc ucuggcugaa guucgugagu gacggcucca     1680

uuaacaaggc aggguuugcc gucaauuucu uuaaagaagu ggaugagugc agccgcccaa     1740

accggggcgg uugugagcag aggugcuuga acacucuggg guccuacaag uguaguugcg     1800

accccggcua ugaacucgcg ccagauaaac gccggugcga ggccgcaugu ggcggguucc     1860

ugaccaagcu gaaugguagc aucaccuccc cgggcuggcc caaagaauac ccacccaaca     1920

agaauugcau uuggcaguug guggccccaa cucaauacag gaucagccuc caguucgacu     1980

uuuucgagac ggaggggaac gauguaugua aguaugacuu uguggaaguc cgcaguggcc     2040

ugaccgcaga uuccaaacug caugguaagu ucugcgggag cgagaaaccc gaagugauca     2100

cuucccagua caauaacaug cgggucgagu uuaagagcga caauaccgug aguaaaaagg     2160

gcuucaaggc ccacuuuuuc agcgacaaag augaauguuc caaggacaac ggcgggugcc     2220

agcaagauug ugugaauacc uuugguaguu augagugcca guguaggagc ggcuucguac     2280

uccaugacaa caaacacgau ugcaaggagg ccggguguga ccacaaaguc acuuccacga     2340

gcggcaccau uacuuccccg aauuggccag auaaguaccc caguaaaaag gaaugcaccu     2400

gggcaaucag cuccacucca ggucaucgcg ugaagcugac cuuuauggag auggacauug     2460

aaagucagcc cgagugcgcc uaugaucacu uggaaguguu cgacgggcgg gaugcgaaag     2520

ccccgguccu gggcagguuc uguggcagca agaaacccga gccagugcuc gcaacggggu     2580

cccgcauguu ucugcgguuc uacagcgaca acagugugca gaggaagggu uuucaagccu     2640

cccaugccac cgagugcggc gggcagguac gcgcagacgu caaaacuaag gaucuguaua     2700

gccacgcgca guucggcgac aauaacuacc ccgguggggu ggauugugaa ugggugaucg     2760

ucgccgagga aggcuacggc guggaguugg uauuucagac cuucgaagug gaggaggaaa     2820

cugacugcgg guaugauuac auggagcugu uugacgguua ugauuccacc gcaccaaggc     2880

ucggccggua cugugggagc ggucccccag aagaggucua uagugccggc gacuccgugc     2940

uggugaaguu ccacagcgau gacacgauua ccaaaaaggg cuuucaucuc agguacacca     3000

guacuaaauu ccaagauacu cugcacuccc gcaagugagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  4488
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt7)

<400>  4488
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggca ccaggugccu gcucgcacug uugcugcccc      120

agguccuccu ggguggggcc gcgggcuugg ugccagagcu ggggcggcgc aaguucgccg      180

cagccagcuc cggcaggccg aguagccaac ccuccgacga aguacucagu gaguuugaac      240

ugcggcugcu cagcauguuc ggucugaaac agcgcccaac ucccuccagg gaugcagugg      300

ucccacccua cauguuggac cuguaucggc gccacagcgg gcagccaggc uccccggccc      360

ccgaucauag gcucgagcgg gcggccaguc gcgcaaacac cgugaggagc uuucaccaug      420

aagagucccu ggaggaacug ccagagacga gcggcaagac uacccggcgc uucuuuuuca      480

auuugaguuc cauccccacc gaagaguuua uuacuagcgc cgagcuccag guguucaggg      540

aacaaaugca ggacgcccug gggaacaauu ccaguuuuca ccaucggauc aacauuuacg      600

agaucauuaa accagcaacc gccaauagca aguuccccgu cacgcgccug cucgauacua      660

ggcuggugaa ccagaaugcg ucccgguggg aauccuuuga cguaaccccg gccgugaugc      720

gcuggacugc acagggucac gccaaccacg gcuucgucgu ggagguggca cauuuggaag      780

agaaacaagg ggucaguaag aggcacgugc ggaucuccag gagccugcau caggaugagc      840

acaguugguc ccagauccgc ccccuccugg uaaccuucgg ccacgacggu aaggggcauc      900

cacugcacaa acgggaaaag aggcaggcca aacauaagca acgcaaacgg cucaagagca      960

gcuguaaaag gcaccccuug uauguggauu uuuccgacgu cggcuggaau gauuggauug     1020

uggccccacc cggcuaccau gcguucuauu gccacgggga guguccauuu ccgcuggcag     1080

accaccugaa caguaccaau caugccaucg ugcagacgcu cgucaacagc gugaauagca     1140

agauucccaa ggccugcugu guaccaacug aacugagcgc aaucaguaug uuguaccugg     1200

augagaacga aaaagugguc cucaagaauu aucaggacau gguggucgag gguugcggcu     1260

gucgcugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  4489
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt7)

<400>  4489
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auccccggca acaggaugcu gauggugguc cuccugugcc      120

agguguugcu cgggggugcc agccacgcau cccugauucc agagaccggc aagaaaaagg      180

uagccgaaau ccaagggcau gcgggcgguc ggcgcagugg gcagagccac gagcuguuga      240

gggacuucga agccacucug cuccagaugu uuggccugcg gcgcaggccg cagcccucca      300

aaagugcagu gauuccagau uacaugcggg accuguaucg ccuccaaagc ggcgaggaag      360

aggaggaaca gauccauucc accgggcugg aguaccccga aaggccagcc agccgggcaa      420

auacgguccg cuccuuccac caugaggagc acuuggaaaa cauucccggu accagugaga      480

auagcgccuu uagguuccug uuuaaccucu ccagcauccc agaaaaugag gugaucaguu      540

ccgcggaacu gcggcuguuc cgcgaacagg uggaucaggg cccggacugg gagagggggu      600

uucaccggau uaacaucuau gaggucauga agcccccagc cgagguggua cccggccauu      660

ugauuacucg ccuccuggau accaggcugg ugcaccauaa ugucacucgg ugggaaaccu      720

ucgacgugag cccagcagug cuccgcugga cgagggagaa acaacccaac uacggucugg      780

ccaucgaagu cacucacuug caccagaccc ggacucauca ggggcagcac gugaggauuu      840

cccgcagucu gccgcaaggc agcggcaauu gggcccagcu ccggccccug cugguaaccu      900

uugggcauga ugguaggggc cacgcauuga cccgccggag gcgcgccaag cgguccccaa      960

agcaucacag ccagagggcg cggaaaaaga acaaaaauug ucgcaggcac agucucuaug     1020

uggacuucuc cgaugucggg uggaacgacu ggaucguggc acccccaggc uaccaagccu     1080

uuuauugcca uggugauugu cccuucccac uggccgacca ccugaauagc acgaaccaug     1140

caauugugca gacucucguc aauaguguga acuccagcau cccgaaggcc ugcuguguac     1200

ccaccgagcu gagcgccauc uccauguugu accuggauga guacgacaaa gugguccuca     1260

agaacuauca ggaaauggug gucgagggcu gcgggugucg gugaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  4490
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt7)

<400>  4490
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggccugg ggaggcgggc ccaguggcuc ugcugguggu      120

ggggucuguu guguagcugc uguggcccac cgccccugcg cccaccccuc ccagcagccg      180

cggccgcagc cgcagggggc caacuguugg gugacggggg cucccccggc aggaccgagc      240

agccaccgcc caguccacag agcuccagug gguuccugua ccggcgccuc aagacucagg      300

agaaaaggga aaugcaaaag gaaauccuga gcgugcuggg ucucccccac cggccacgcc      360

cccugcaugg cuugcagcag ccgcagcccc cagcccugag gcaacaggag gaacagcagc      420

aacagcagca acucccccgc ggggagccac ccccaggccg gcugaaaucc gcgccgcugu      480

uuauguugga ucucuauaac gcccugagcg cagacaauga ugaggacggu gccuccgaag      540

gggagaggca gcagaguugg ccccacgaag ccgcaagcuc cagccagcgg cgccaaccac      600

ccccaggcgc cgcgcauccc cugaacagga agagucuccu ggccccgggc uccgggagcg      660

guggcgcauc cccauugacc agugcccagg auagcgcauu ccugaaugac gccgauaugg      720

ucauguccuu ugugaaccuc guagaguacg acaaagaguu cagcccccgg cagcgccacc      780

auaaggaauu uaaguucaau cugagucaga uucccgaggg ggaagugguc acggccgcgg      840

aguuuaggau cuauaaagau ugcgugaugg gcuccuucaa gaaccaaacu uuucugauua      900

gcaucuacca gguguugcag gaacaccagc accgggacag ugaucucuuc cugcuggaca      960

cccgcgucgu gugggcaucc gaggaggguu ggcucgaauu ugauauuacc gccacuagca     1020

aucugugggu agugacccca caacauaaca ugggcuugca gcugagcguc gugacgaggg     1080

acggggugca cguccauccc cgggccgcag gccucguggg gagggacggu ccauaugaua     1140

aacagccguu caugguagcc uucuuuaagg uguccgaggu ccacgugcgc acuacccgga     1200

gugcgagcuc caggcgccgg cagcaaagca ggaaucgcag uacucagucc caggacgugg     1260

cccgggucag cuccgcaagu gauuacaaca gcuccgaacu gaaaaccgcc uguaggaagc     1320

acgagcugua ugugagcuuc caagacuugg gcuggcagga uuggaucauc gcacccaaag     1380

gguacgccgc caauuacugc gacggcgaau guaguuuucc acucaacgca cauaugaaug     1440

ccaccaacca cgcgauugua cagacgcugg ugcaucugau gaaucccgag uaugucccaa     1500

agcccugcug ugccccgacu aagcucaacg caaucuccgu gcuguacuuc gaugacaaca     1560

gcaaugucau uuugaaaaag uaucggaaca ugguggugcg cgccugcggu ugccacugag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  4491
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt7)

<400>  4491
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugagga gccugcgggc cgcagcgccc cauuccuucg      120

ucgcccucug ggccccacug uuuuugcugc gcagugcacu cgccgacuuc agccuggaua      180

acgaggugca cuccaguuuu auccauaggc gguugcgcag ccaggaaagg cgggagaugc      240

aacgcgaaau ucuguccauc cucggccugc cgcacaggcc ccggccacau cugcagggga      300

agcacaauag cgcacccaug uucaugcucg accuguacaa cgccauggcg guagaggaag      360

guggcgggcc aggcggucag ggguuuuccu aucccuacaa agccguguuc aguacccagg      420

gcccaccguu ggcaagccug caagauuccc acuuucucac ugacgccgau auggucauga      480

gcuucgugaa ucugguggag caugacaagg aguuuuucca cccccgcuau caucacaggg      540

aauuucgguu cgaucugagu aaaauuccag agggcgaagc cgucaccgca gccgaguucc      600

gcaucuacaa ggacuauauu agggagcggu uugauaacga aacguuccgc aucuccgugu      660

accagguauu gcaggagcac cucgggaggg aaagcgaccu guuucugcuc gauucccgga      720

cucugugggc gagugaggaa gguugguugg uguucgacau caccgccacc agcaaucauu      780

gggucgugaa cccccgccac aaucugggcc uccagcuguc cguggagacu cuggaugggc      840

aaagcauuaa cccaaaauug gcaggccuca ucgguaggca ugggccccag aauaagcagc      900

cguuuauggu cgccuucuuu aaggcaaccg aggugcacuu ccggaguauu agguccacgg      960

gcagcaaaca gcgcagucaa aaccggucca agacucccaa aaaucaggaa gcccugagga     1020

uggccaacgu agcggagaau agcagcuccg accagcgcca agcaugcaag aaacaugaac     1080

uguaugugag uuuucgggac cucggcuggc aggauuggau cauugcccca gagggguacg     1140

ccgcauacua uugugaaggu gagugcgccu ucccccugaa cagcuacaug aaugcgacca     1200

accacgccau cguccagacu uuggugcacu uuauuaaccc agagaccgug cccaagccau     1260

guugcgcacc gacccagcug aaugccaucu ccguccucua uuucgacgau agcaguaacg     1320

ugauccugaa aaaguacagg aauaugguag ugcgcgcaug uggcugccau ugaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  4492
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt7)

<400>  4492
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggccagcg cagcccugcu cugccuguug cugaccgcgg      120

ccgcauucag uccccagggc cucgcccaac caguggggau caacacuucc accacguguu      180

gcuacagguu uauuaauaaa aagaucccga aacagcggcu ggagagcuau cgcaggacua      240

ccuccaguca cuguccccgg gaagcaguca uuuucaagac caaauuggac aaggagaucu      300

gcgccgaucc aacucagaag ugggugcagg acuuuaugaa acaucuggau aagaaaaccc      360

aaacgcccaa gcucugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  4493
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt7)

<400>  4493
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucaccc ugaucauuuu gcugcccgug gucagcaagu      120

ucuccuuugu gagucucagc gccccacagc acugguccug cccggagggc acucuggcag      180

ggaacgguaa uaguaccugu guaggccccg ccccauucuu gaucuuuagc caugggaacu      240

ccauuuucag gaucgacacg gaaggcacua auuacgagca acuggugguc gacgcgggug      300

ugagcgugau uauggacuuu cacuauaacg aaaaacggau cuacuggguc gaucucgagc      360

gccagcugcu gcagagggug uuccucaaug ggucccggca ggaacgcgua ugcaacaucg      420

agaagaaugu gaguggcaug gccauuaacu ggaucaauga ggaagucauu uggagcaacc      480

aacaggaggg caucauuacc gugaccgaca ugaaagggaa uaacucccau auccuguuga      540

gcgcacugaa guaucccgcc aauguggcag ucgauccagu ggaaagguuu auuuucugga      600

guuccgaggu agccgguagc cucuaccggg cggaccugga uggcgugggg gucaaagccc      660

uguuggagac uuccgaaaag aucaccgcag ugagucucga cgugcuggau aagcgccugu      720

uuuggaucca guauaacagg gagggcagca auucccucau uuguagcugc gacuacgaug      780

gugggagugu ccacaucucc aaacauccca cgcagcacaa ccuguucgcc augagcuugu      840

uuggcgaccg gauuuucuau aguacuugga agaugaaaac caucuggauu gccaacaagc      900

acacuggcaa agauauggug cgcaucaauc ugcauuccag cuucguacca cucggggaac      960

ugaagguggu ccacccgcug gcacaaccca aagccgagga cgacaccugg gaaccagagc     1020

agaaguugug uaagcucagg aaagguaacu gcagcuccac cguguguggc caggaucugc     1080

agagucaucu gugcaugugu gcggaggggu acgcccucag ccgggaccgc aaguacugcg     1140

aagaugucaa ugagugcgca uuuuggaacc acggcuguac gcuggguugc aaaaauacuc     1200

ccggcuccua uuacuguacc ugcccagugg gguucguguu gcugcccgac ggcaagaggu     1260

gucaccaacu cguaagcugc ccgcggaacg ugagugaaug uucccaugau ugcguccuga     1320

cuagcgaggg gccccugugu uuuugcccag aagguuccgu guuggagcgc gacggcaaaa     1380

ccugcagugg guguagcucc cccgauaaug gcgguugcag ccagcucugu gucccacuga     1440

gucccguguc cugggagugc gacuguuucc caggcuauga ucugcagcuc gacgaaaaga     1500

gcugcgccgc auccgggccg caacccuuuc uguuguucgc caacagucag gauaucaggc     1560

acaugcauuu ugacggcacc gacuacggga cucugcucag ccagcagaug ggcauggugu     1620

augcccugga ucacgaccca guagagaaua agauuuacuu cgcgcauacg gcacugaaau     1680

ggaucgaacg ggccaacaug gaugguuccc aacgcgagag guugauugaa gagggggugg     1740

acguccccga gggccuggcc guggauugga ucggucggag guuuuauugg accgaccgcg     1800

gcaagagccu cauugggcgg agugaucuga auggcaaaag guccaagauc aucacuaaag     1860

aaaacauuag ccagccacgc gggaucgcag uccaccccau ggccaagcgg cuguucugga     1920

ccgacaccgg cauuaauccg aggaucgagu ccagcagucu ccaggguuug gggcgccugg     1980

ugauugcgag cuccgaucuc aucuggccaa guggcauuac uaucgacuuu cugacggaua     2040

agcuguacug gugugacgcc aaacagagcg ugaucgaaau ggcaaacuug gauggcucca     2100

agcggaggcg gcugacccaa aaugacguag ggcaccccuu cgccgucgca guguuugagg     2160

acuacgugug guucagcgau ugggccaugc ccuccgucau gcgcgugaac aaaaggacug     2220

guaaggaccg ggugcgccuc cagggcagua ugcugaaacc aagcucccuc guagucgugc     2280

auccccuggc caagccaggg gcagauccgu gcuuguauca gaacggcggu ugugagcaca     2340

uuugcaagaa aaggcugggg accgccuggu guaguugccg ggaaggcuuc augaaggcga     2400

gcgacggcaa aaccugccug gcccucgaug ggcaucagcu guuggccggu ggcgaggugg     2460

accugaagaa ucaagucacu ccccucgaua uccuguccaa aacgcgcgug agcgaagaca     2520

acauuaccga gagucagcac augcucguag cagaaaucau gguguccgau caggacgauu     2580

gugccccagu cgggugcagc auguacgcaa gguguauuuc cgagggcgag gacgcgacuu     2640

gccagugucu gaaggguuuu gccggggacg gcaaauugug cagcgauauc gacgaaugug     2700

agaugggcgu gcccgugugc ccacccgcaa guuccaagug uaucaauacc gaaggggguu     2760

augucugccg gugcagcgag ggcuaccaag gggauggcau ucacugucug gacaucgaug     2820

aaugccagcu gggugagcau aguugugggg agaacgccuc cugcacuaau accgaaggcg     2880

gcuauacgug uaugugcgcc gggaggcuca gcgagccggg ucugauuugu ccagacucca     2940

cucccccacc ccacuugcgc gaagaugacc aucacuacag cgugcggaac agugauagcg     3000

agugcccgcu gucccaugac ggcuauuguc uccacgaugg gguaugcaug uacaucgaag     3060

cacuggacaa guacgccugc aauugugugg ucggcuauau uggugagagg ugccaguacc     3120

gcgaucugaa auggugggag cuccggcacg cgggccaugg gcaacagcag aaggugaucg     3180

uggucgccgu guguguagug guccugguga uguugcugcu ccugaguuug uggggcgcac     3240

acuauuacag gacccagaaa cugcucagca agaaccccaa aaauccauau gaagagucca     3300

gccgcgacgu gcgguccagg cgccccgccg acaccgaaga ugggaugagu agcugcccac     3360

aacccugguu cgucgugauc aaggagcauc aggaccugaa gaacgguggc cagccaguag     3420

ccggggagga uggccaggca gccgacgguu ccaugcaacc gacuagcugg cggcaggaac     3480

cccagcugug uggcaugggg accgagcagg gcugcuggau uccagugagu uccgauaaag     3540

ggagcugucc ccaagucaug gaaagguccu uucacaugcc aaguuacggu acgcagaccc     3600

ucgagggcgg gguggaaaag ccccacagcc uguuguccgc gaauccgcug uggcagcaac     3660

gcgcccucga ucccccacau cagauggagc ugacucagug aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  4494
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt7)

<400>  4494
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggca ggcggaugga gaugcugugc gcagggcgcg      120

ugcccgcccu ccuguugugc cuggguuucc accuccugca ggcggucuug agcacuaccg      180

ugaucccauc cugcauuccg ggcgaaagua gcgacaacug uacggcccug guacaaacug      240

aggauaaucc caggguggca caggucucca ucaccaagug caguagcgac augaacgggu      300

acugucucca uggccagugc auuuaucugg uggauauguc ccagaauuac ugucggugcg      360

aaguggguua uaccgggguc cgcugugagc acuuuuuccu gacugugcau caaccacuca      420

gcaaagaaua cguagcccug accgugaucu ugauuauccu guuucucauc acggucgugg      480

gcuccacuua uuacuucugu aggugguauc ggaaccgcaa gaguaaagag cccaagaaag      540

aguacgaaag ggugaccagc ggcgacccag agcugcccca ggucugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  4495
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt7)

<400>  4495
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgagggcg aaaucaccac uuucaccgca cugacggaga      120

aguuuaaccu gcccccaggg aauuacaaaa agccgaaacu cuuguauugc agcaacggug      180

gccacuuccu gaggauucuc cccgacggga cuguggaugg cacccgggac cgcuccgauc      240

agcauaucca acugcaguug agugccgaaa gcgucgguga gguguacauu aaguccaccg      300

aaacugggca guaucuggcg auggacaccg auggccuccu guacggcagu cagacgccaa      360

augaggagug ucuguuucuc gaaaggcugg aggaaaacca cuauaauacu uacaucagca      420

aaaagcaugc cgagaagaac ugguucguag gguugaaaaa gaaugguucc ugcaaacggg      480

gcccccgcac ccacuauggg caaaaggcaa uucuguuucu cccacugccc gugagcuccg      540

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  4496
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt7)

<400>  4496
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggcgucg gggguggcga cguggaggau guaaccccca      120

ggccaggggg cugccagauc agcggucgcg gggcccgggg cuguaacggc auuccggggg      180

cagccgcgug ggaagccgca cugcccaggc ggcgcccaag gcggcacccc uccgugaauc      240

cacgcaguag ggccgcaggu agcccccgga cucgcggcag gcggaccgag gaacgcccau      300

ccgggaguag gcucggcgac cggggucgcg ggagggcccu gccgggcggc cgguugggug      360

ggcgcggcag ggggcgggcg cccgagaggg ucggcggucg cggccggggg aggggcacgg      420

ccgcaccacg cgccgccccc gcagcccggg ggagcaggcc aggucccgcg ggcacuaugg      480

ccgcaggguc caucaccacc cugccggccc uccccgaaga uggcgguagc ggcgcauucc      540

cacccgggca uuuuaaggac ccaaaacgcc uguacugcaa gaacggcggg uucuuuuugc      600

ggauucaccc cgauggcagg guggacggug ugcgggagaa auccgaucca cauaucaagc      660

ugcaacucca ggccgaggaa cgcggggucg ugaguauuaa aggcguaugu gccaauaggu      720

aucuggcgau gaaggaggac ggucggcugc ucgcaagcaa gugcgugacu gaugaauguu      780

ucuuuuucga gcgccuggag uccaacaauu acaacaccua uaggagccgg aaauacacga      840

guugguaugu cgccuugaag cgcacuggcc aguacaaacu gggguccaag accggcccgg      900

ggcagaaagc cauccucuuu cugcccauga gcgcaaaguc cugaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  4497
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt7)

<400>  4497
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uccugaccug gauucucccc acucuguugu      120

acaggagcug cuuccauauc auuugucugg ugggcaccau cucccucgcc ugcaacgaca      180

ugacgccaga gcagauggca acuaauguca acuguaguag cccggaacgg cacacccgcu      240

ccuaugauua cauggaaggg ggugacauua gggugcggcg ccuguuuugc aggacccaau      300

gguauuugcg gaucgauaaa cgcggcaagg uaaaagggac ucaggagaug aagaauaacu      360

acaauaucau ggagauuagg accguggccg ucggcaucgu ggcgauuaaa gguguggaaa      420

gugaguucua ucuggccaug aacaaggagg ggaagcucua cgccaaaaag gaauguaaug      480

aggacugcaa cuuuaaagaa cugauccugg agaaucauua uaacacguac gcaagcgcaa      540

aguggacuca caauggcggc gagauguucg ucgcccucaa ccagaaaggg auucccgugc      600

gggguaagaa aaccaagaag gaacagaaaa cugcgcauuu ucugccaaug gccaucaccu      660

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  4498
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt7)

<400>  4498
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugcucc ccagcguggu ccugaaauug uuccuggccg      120

cagugcucuc cgcccuggua accggcgaga guuuggaaag gcugcggcgc gggcucgcgg      180

ccgguacuag caacccagac ccgcccaccg uguccacgga ucagcugcug ccacucggcg      240

ggggcaggga ccggaagguc cgcgaucugc aagaggcaga cuuggaucug cucaggguga      300

cucugaguag caaaccccag gcccuggcaa ccccaaauaa ggaggaacac gguaaacgga      360

agaagaaagg gaagggcuug ggcaaaaagc gcgaccccug ccucaggaaa uacaaggauu      420

uuuguaucca uggggaaugc aaauauguga aggagcugcg ggccccaucc uguauuugcc      480

acccggguua ccauggcgag cgcugucacg ggcugagccu ccccgucgaa aacaggcugu      540

auaccuacga ccauacuacc aucuuggcgg ugguagccgu gguccugucc agugugugcc      600

uccuggugau ugucggccug uugauguucc gguaucaccg cagggguggg uacgaugugg      660

agaaugaaga gaagguaaaa cucggcauga cgaacagcca cugaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  4499
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt7)

<400>  4499
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccuguug cugcagcacg      120

uccuccugca uuugcugcuc cugccaaucg caauuccgua cgccgagggc caaaggaaac      180

ggcgcaacac uauccacgaa uuuaagaaaa gcgcgaagac cacgcugauu aaaaucgacc      240

ccgcccucaa gauuaagacu aaaaagguga auaccgcaga ucagugcgcc aacaggugua      300

cccggaauaa agggcugcca uucacuugca aggcauucgu auuugacaaa gcccgcaagc      360

aguguuugug guuccccuuu aacuccauga guagcggugu gaaaaaggag uucggccaug      420

aauuugaucu guaugagaau aaggacuaca ucaggaacug caucauuggg aaaggccggu      480

ccuauaaggg uaccgucagu aucacgaaaa gcgggauuaa gugucagcca ugguccagca      540

ugauccccca cgaacauucc uuccucccaa guagcuaccg cggcaaagau cugcaagaga      600

auuauugcag gaacccgcgg ggcgaggaag ggggucccug guguuuuacu uccaauccag      660

aggugcgcua cgaagugugc gacauucccc aguguagcga ggucgagugc augaccugca      720

acggcgaaag uuauaggggg cugauggauc acacugaguc cggcaagauc ugucagcggu      780

gggaccacca gaccccacau cgccacaagu ucuugcccga aagguacccg gauaaagguu      840

uugacgauaa uuacugccgg aaccccgacg ggcaaccacg ccccuggugu uauacccucg      900

auccacauac gaggugggag uacugcgcga uuaagacuug ugccgacaau accaugaacg      960

acacugaugu gccccuggaa accaccgagu gcauccaggg ccagggcgag ggguaucggg     1020

guacuguaaa uacgaucugg aacggcauuc caugucagcg cugggacagc caauacccgc     1080

acgaacacga uaugaccccc gagaacuuca aaugcaagga ccugagggaa aauuauuguc     1140

ggaacccaga uggguccgag agucccuggu gcuucacuac cgacccaaau aucagggugg     1200

gcuacugcag ccagauuccc aacugugaua ugucccaugg ucaggacugc uaucgcggca     1260

augggaaaaa cuacaugggc aaucucagcc aaacccggag ugggcugacu uguuccaugu     1320

gggauaagaa cauggaagac uugcacaggc auaucuuuug ggagccggau gcaagcaagc     1380

ugaaugagaa cuacugccgc aauccagacg acgaugccca cggucccugg uguuauacgg     1440

gcaacccccu cauuccaugg gacuacugcc ccaucagucg gugugaaggg gauaccacuc     1500

caaccaucgu caaucuggac cauccgguga uuuccugcgc caaaaccaag cagcugaggg     1560

uggucaacgg cauccccacu cgcacgaaua uugguuggau ggugagcuug cgguauagga     1620

acaaacacau cuguggcggg agccucauua aggaguccug gguacugacc gcacggcagu     1680

gcuucccaag ucgcgaucug aaagacuacg aagccuggcu cggcauccac gaugugcaug     1740

ggaggggcga cgagaagugu aagcaggucc ugaacgugag ccaauuggug uauggucccg     1800

aaggguccga ucugguccuc augaaacugg cgcggccagc cgugcuggac gauuuuguaa     1860

gcacuaucga cuugcccaau uacggcugca ccauuccgga gaagaccagu ugcuccgugu     1920

augguugggg cuacacuggg cucaucaacu acgauggccu gcugcgcguc gcacaccucu     1980

auauuauggg gaaugagaaa uguagccagc aucacagggg caaggugacg cugaacgaau     2040

ccgagaucug cgccggugca gagaaaauug ggaguggccc augugaaggc gacuacgggg     2100

gucccuuggu cugcgagcag cacaagaugc ggauggugcu gggcgugauc guaccagggc     2160

gcggcugugc cauucccaau aggccgggua ucuucgugcg ggucgccuau uacgcgaaau     2220

ggauccauaa gauuauccuc accuauaagg ugccccagag cugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  4500
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt7)

<400>  4500
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggcag ccgcgaucgg cauugaccug gggaccacuu      120

acagcugcgu gggugucuuc cagcacggca aaguggagau cauugccaac gaucaaggga      180

auaggaccac gcccuccuau guagcauuua cugacaccga acggcucauc ggcgaugccg      240

caaagaacca gguggcccug aauccacaga acaccgucuu cgacgcgaaa cgcuugauug      300

guaggaaguu uggggauccg guggugcaga gugacaugaa acauuggccc uuccaaguca      360

ucaaugaugg cgacaagcca aaggugcagg uaagcuacaa aggcgagacu aaggccuuuu      420

aucccgaaga gaucuccagu auggugcuga ccaaaaugaa ggaaauugca gaggccuacc      480

ucggguaucc agucacgaac gccgugauca cugugcccgc auacuucaau gauagccagc      540

ggcaggccac caaagacgcg ggugucauug ccggccugaa cguguugcgc aucauuaaug      600

agccaacugc agccgcaauc gccuaugggc uggauaggac cggcaagggu gaacggaacg      660

uacucauuuu ugaccucggg ggcggcaccu ucgauguguc cauccugacg aucgacgacg      720

ggauuuuuga ggucaaagcc acugcgggug auacccaccu gggcggggaa gacuucgaua      780

aucgccuggu gaaccauuuu guggaggagu ucaagaggaa gcacaaaaag gacaucagcc      840

aaaauaaacg ggcaguccgc agguugcgga cugccuguga acgcgccaag aggacccugu      900

ccaguagcac ccaggcaucc cucgagauug auagccuguu cgaaggcauc gacuuuuaca      960

cuagcauuac gcgggcccgc uucgaggaac ugugcuccga uuuguuuagg agcacccucg     1020

agccggugga gaaagcgcug cgggacgcca agcuggauaa ggcacagauc caugaccucg     1080

uacugguggg uggcuccacu cgcaucccca aaguccagaa guugcugcaa gauuucuuua     1140

acgggaggga ccucaauaaa aguauuaacc cagacgaagc cguggcauac ggcgccgccg     1200

uccaggcagc cauccugaug ggggauaaga gcgagaacgu gcaggaccug uugcuccugg     1260

auguggcgcc ccugucccuc ggucuggaaa ccgccggcgg gguaaugacc gcauugauua     1320

aacggaauag cacuauccca acgaagcaaa cccagauuuu cacuaccuau agugacaacc     1380

agcccggcgu gcugauccag gucuacgagg gugaaagggc caugaccaag gauaauaacc     1440

uccugggccg cuuugagcug uccgggaucc cgcccgcccc acggggcgug ccccaaauug     1500

aggucacuuu cgacaucgau gcaaauggga uuuugaacgu gacggcgacc gacaaaagca     1560

cuggcaaggc caauaaaauc accauuacua acgauaaggg uaggcucagu aaagaagaga     1620

ucgaacgcau ggugcaggag gcagaaaagu auaaggccga ggacgaggua cagcgggaaa     1680

ggguguccgc caaaaaugca cuggagagcu acgccuuuaa caugaagagu gcggucgaag     1740

augaggggcu gaaaggcaag auuuccgagg ccgacaaaaa gaaagugcuc gauaaguguc     1800

aggaagucau caguuggcug gacgcaaaua ccuuggccga gaaggacgag uucgaacaca     1860

aacgcaagga acuggagcaa gugugcaacc caaucauuag cggucucuau cagggcgccg     1920

ggggccccgg gccaggcggu uuuggggcac agggcccgaa aggcgggucc gguagcggcc     1980

ccacgaucga ggaaguggau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4501
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt7)

<400>  4501
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggcag ccgcgaucgg cauugaccug gggaccacuu      120

acagcugcgu gggugucuuc cagcacggca aaguggagau cauugccaac gaucaaggga      180

auaggaccac gcccuccuau guagcauuua cugacaccga acggcucauc ggcgaugccg      240

caaagaacca gguggcccug aauccacaga acaccgucuu cgacgcgaaa cgcuugauug      300

guaggaaguu uggggauccg guggugcaga gugacaugaa acauuggccc uuccaaguca      360

ucaaugaugg cgacaagcca aaggugcagg uaagcuacaa aggcgagacu aaggccuuuu      420

aucccgaaga gaucuccagu auggugcuga ccaaaaugaa ggaaauugca gaggccuacc      480

ucggguaucc agucacgaac gccgugauca cugugcccgc auacuucaau gauagccagc      540

ggcaggccac caaagacgcg ggugucauug ccggccugaa cguguugcgc aucauuaaug      600

agccaacugc agccgcaauc gccuaugggc uggauaggac cggcaagggu gaacggaacg      660

uacucauuuu ugaccucggg ggcggcaccu ucgauguguc cauccugacg aucgacgacg      720

ggauuuuuga ggucaaagcc acugcgggug auacccaccu gggcggggaa gacuucgaua      780

aucgccuggu gaaccauuuu guggaggagu ucaagaggaa gcacaaaaag gacaucagcc      840

aaaauaaacg ggcaguccgc agguugcgga cugccuguga acgcgccaag aggacccugu      900

ccaguagcac ccaggcaucc cucgagauug auagccuguu cgaaggcauc gacuuuuaca      960

cuagcauuac gcgggcccgc uucgaggaac ugugcuccga uuuguuuagg agcacccucg     1020

agccggugga gaaagcgcug cgggacgcca agcuggauaa ggcacagauc caugaccucg     1080

uacugguggg uggcuccacu cgcaucccca aaguccagaa guugcugcaa gauuucuuua     1140

acgggaggga ccucaauaaa aguauuaacc cagacgaagc cguggcauac ggcgccgccg     1200

uccaggcagc cauccugaug ggggauaaga gcgagaacgu gcaggaccug uugcuccugg     1260

auguggcgcc ccugucccuc ggucuggaaa ccgccggcgg gguaaugacc gcauugauua     1320

aacggaauag cacuauccca acgaagcaaa cccagauuuu cacuaccuau agugacaacc     1380

agcccggcgu gcugauccag gucuacgagg gugaaagggc caugaccaag gauaauaacc     1440

uccugggccg cuuugagcug uccgggaucc cgcccgcccc acggggcgug ccccaaauug     1500

aggucacuuu cgacaucgau gcaaauggga uuuugaacgu gacggcgacc gacaaaagca     1560

cuggcaaggc caauaaaauc accauuacua acgauaaggg uaggcucagu aaagaagaga     1620

ucgaacgcau ggugcaggag gcagaaaagu auaaggccga ggacgaggua cagcgggaaa     1680

ggguguccgc caaaaaugca cuggagagcu acgccuuuaa caugaagagu gcggucgaag     1740

augaggggcu gaaaggcaag auuuccgagg ccgacaaaaa gaaagugcuc gauaaguguc     1800

aggaagucau caguuggcug gacgcaaaua ccuuggccga gaaggacgag uucgaacaca     1860

aacgcaagga acuggagcaa gugugcaacc caaucauuag cggucucuau cagggcgccg     1920

ggggccccgg gccaggcggu uuuggggcac agggcccgaa aggcgggucc gguagcggcc     1980

ccacgaucga ggaaguggau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4502
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt7)

<400>  4502
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaccgcaa agggcaucgc cauugggauc gaccugggua      120

cuaccuacag cugcgugggc gucuuccagc acgggaaagu ggagauuauc gcgaacgauc      180

aaggcaauag gacgacuccc uccuauguag ccuuuaccga caccgaacgg cucauuggug      240

augcagccaa gaaccaggug gcaaugaauc cacagaacac ugucuucgac gccaaacgcc      300

ugaucgggag gaaguuuaau gauccggugg ugcaggcgga caugaaauug uggcccuucc      360

aagucaucaa cgagggcggc aagccaaagg ugcugguaag uuacaaaggg gaaaauaagg      420

ccuuuuaucc cgaggaaauu agcuccaugg ugcucaccaa acugaaggag acggcagagg      480

ccuucuuggg ucauccaguc acuaacgccg ugaucaccgu gcccgcauac uuuaaugaua      540

gucagcggca ggccacuaaa gacgcgggcg ucauugccgg gcugaacgug cuccgcauca      600

uuaaugaacc aaccgcagcc gcaaucgccu auggccugga uaaggguggg cagggcgaga      660

ggcacguacu gauuuucgac cucggcgggg guaccuuuga ugugagcauc cugacgaucg      720

acgauggcau uuucgaaguc aaagccacug cgggggacac ccauuugggc ggugaggacu      780

uugauaaccg gcuggugucc cacuucgugg aggaguucaa gcgcaagcau aaaaaggaca      840

ucagccaaaa uaaaagggca guccggcgcc ucaggacugc cugugagcgg gccaagcgca      900

cccuguccag uagcacccag gcaaaccugg aaauugauuc cuuguacgag ggcaucgacu      960

uuuauacuag cauuacgagg gcccgguucg aagaacucug cgcggaucug uuucgcggga     1020

cccuggagcc gguggaaaaa gcccucaggg acgcaaagau ggauaaggcc aaaauccacg     1080

acaucguacu ggugggcggg aguacucgga uucccaaggu ccagcgcuug cugcaggauu     1140

acuucaaugg uagggaccuc aacaaaucca ucaacccaga ugaggcagug gccuacggcg     1200

ccgcagucca agccgcgauu cugauggggg acaagagcga aaaagugcag gaccuguugc     1260

uccuggaugu ggcaccccug ucccucggcc uggagaccgc cgguggcgua augaccgccu     1320

ugaucaagcg gaauaguacu auuccaacga agcagaccca aaucuuuacu accuauagcg     1380

acaaccagcc cggggugcug auccaggucu acgaaggcga gagggccaug accaaagaua     1440

auaaccuccu ggggcgcuuc gaccugacug gcauuccgcc cgcaccacgg ggugugcccc     1500

agaucgaggu cacguuugau auugacgcga augggaucuu gaacgugacc gccacugaua     1560

aguccaccgg caaagugaau aagauuacua ucaccaacga caaagguagg cucagcaagg     1620

aagagauuga acgcauggua cuggaugcag agaaguauaa agccgaagac gaggugcaac     1680

gggagaagau cgccgccaaa aaugcacugg aaaguuacgc guucaacaug aaguccgucg     1740

ugagcgauga gggccucaaa gggaagauca gugaauccga caaaaauaag auucuggaua     1800

aguguaacga guugcugagc uggcucgagg ucaaucagcu ggccgaaaaa gacgaguuug     1860

accacaagag gaaagaacug gagcagaugu gcaacccaau cauuacgaag uuguaucagg     1920

gcggguguac cggccccgca ugcgguacug gguacgugcc aggccgcccg gccaccggcc     1980

ccacuaucga agagguggau ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4503
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt7)

<400>  4503
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgccaggg gccccgcaau cgggauugac cuggguacca      120

cuuacuccug cgugggcguc uuccagcacg ggaaggugga gaucauugcc aacgaucagg      180

gcaaucggac cacgccaagu uauguagcgu uuacugacac cgaacgccuc aucggugaug      240

ccgccaaaaa ccagguggca augaauccga ccaacacuau uuucgacgca aagaggcuga      300

ucgggcggaa auuugaggau gccaccgucc agagcgacau gaagcauugg cccuuccgcg      360

ugguguccga aggcggcaaa ccaaaggucc agguggagua caagggggaa acgaaaaccu      420

uuuuccccga ggagaucagu agcaugguau ugacuaagau gaaagaaauu gcggaggccu      480

aucugggugg caaggugcac uccgcaguca ucacugugcc agccuacuuu aaugauagcc      540

aaaggcaggc caccaaagac gcagggacca uuacgggccu caacgugcug cggaucauua      600

augaacccac ugccgcggcc aucgcauaug guuuggauaa gaaagggugu gccggcggcg      660

agaagaacgu ccugauuuuc gaccucgggg guggcaccuu ugaugugucc auccugacua      720

ucgaggacgg gauuuucgaa guaaagagua ccgcaggcga uacccaucug gguggcgagg      780

acuuugacaa ucgcauggug agccaccucg ccgaagaguu caaaaggaag cauaaaaagg      840

auaucgggcc aaacaaacgg gccguccgca ggcugcggac ugcgugcgaa cgcgcaaaga      900

ggacguuguc cagcaguacc caggccucca uugagaucga cagccuguac gagggcgugg      960

auuucuauac uuccauuacc cgggcccgcu uugaggaacu caaugcagac cuguucaggg     1020

ggacccugga accgguggag aaggccuugc gggaugcgaa acucgacaag ggucagaucc     1080

aagaaaucgu ccuggugggc gggaguacuc gcauucccaa aauccagaag cugcuccagg     1140

acuuuuucaa cggcaaagag cugaauaaga gcauuaaccc agaugaggcc guagcauacg     1200

gugccgcagu gcaggccgcc aucuugauug gcgauaaguc cgaaaauguc caagaccugc     1260

uccugcugga ugugacgccc uugagccucg ggaucgagac cgcaggcggg gucaugacuc     1320

cacugaucaa aaggaacacc accauuccca cuaagcagac gcagaccuuu acuaccuaca     1380

gugacaacca auccagcgug cuggugcagg uauaugaagg cgagcgggcc augacuaaag     1440

acaauaaccu ccuggguaag uucgauuuga ccgggauccc gcccgcgcca aggggcgugc     1500

cccagauuga agucacguuu gacaucgaug ccaaugguau ucugaacgug accgcagccg     1560

acaaaaguac uggcaaggag aauaagauca ccauuacuaa cgauaaaggg cgccucucca     1620

aggacgauau cgaccggaug guccaggagg ccgaaaggua caaaagcgag gaugaagcaa     1680

aucgcgaccg gguggcggcc aagaacgcac uggagagcua uaccuacaau aucaaacaaa     1740

cgguggagga ugaaaagcug aggggcaaaa uuuccgagca ggacaagaac aagaucuugg     1800

auaaauguca ggaaguaauu aauuggcucg accgcaacca gauggccgag aaggacgaau     1860

augagcacaa acaaaaggag cuggaacggg ugugcaaucc aaucauuagu aaacuguacc     1920

aagggggccc cggugggggc agcggcgggg guggcuccgg ggccagcggc gguccaacca     1980

ucgaggaagu cgauugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  4504
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt7)

<400>  4504
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccag uccugcuacg      120

uggccguagc aagggccggu ggcauugaga ccaucgcgaa cgaauauagu gaucggugua      180

cucccgccug cauuagcuuu gggccaaaga aucgcuccau cggcgcagcc gcaaaaaguc      240

aagugauuag caacgccaag aauaccgucc aggguuucaa aagguuucac gggcgggcgu      300

ucuccgaccc guuuguggag gccgaaaaga gcaaccucgc auacgauauc gugcagcugc      360

ccacgggcuu gacuggcauc aaagucaccu auauggagga agaacgcaau uucaccacug      420

aacaggugac cgccaugcug cucuccaagc ugaaggaaac ggccgagagu guauugaaaa      480

agccaguggu cgacugugug gugagcgucc ccugcuuuua cacugaugca gaaaggcggu      540

ccgugaugga cgccacccaa auugcggggc ugaacugucu ccgccugaug aaugagacua      600

ccgccguagc acuggccuau gguaucuaca aacaggaucu cccagcacug gaggaaaagc      660

ccaggaacgu ggucuucgug gacaugggcc auagcgccua ucaggugagu gucugcgccu      720

uuaaucgggg gaaauugaag gugcuggcga ccgcauucga uacgacucuc ggcggucgca      780

aauuugacga gguacuggug aaccacuucu gugaagaguu cgggaagaag uacaaacugg      840

auauuaaguc caaaaucagg gccuugcucc ggcugagcca ggaaugcgag aagcugaaaa      900

agcucauguc cgccaaugca agugaccugc cauugagcau ugaguguuuu augaacgaug      960

ucgacguguc cggcaccaug aaucgcggca aguuccugga aaugugcaac gaccuccugg     1020

ccagggucga gccgccccug cggagcgugu uggaacaaac uaaacucaag aaagaggaua     1080

ucuacgcggu ggaaauugua gggggugcca cccgcauccc agcagugaag gagaaaauca     1140

guaaguuuuu cggcaaggag cuguccacca cucugaaugc cgacgaagca gucacgaggg     1200

ggugcgcccu ccagugugcc auucugagcc ccgcauuuaa agugcgggag uucaguauca     1260

ccgaugucgu gccauauccc auuuccuugc gcuggaacag cccggccgaa gagggcagcu     1320

ccgacugcga aguguuuagu aagaaccaug cggcccccuu cagcaaagua cugacuuuuu     1380

acaggaagga gccauucacc cucgaggcau auuacuccag cccccaggau cugccauauc     1440

ccgacccagc caucgcccag uuuagugugc aaaaagucac cccgcagucc gaugguagcu     1500

ccaguaaggu gaaggucaaa gugcggguga auguacacgg cauuuucagc gucuccagcg     1560

caagucuggu ggaagugcau aaguccgagg aaaacgagga gcccauggaa acugaccaga     1620

augcgaaaga ggaagagaag augcaagucg aucaggagga gccacacgug gaggaacagc     1680

agcaacagac gcccgccgag aacaaagcag aaagcgagga aauggagacc ucccaggccg     1740

ggaguaagga caaaaagaug gaucagccac cccaagccaa gaaagcaaag gugaaaacua     1800

gcaccguaga cuugccgauc gagaaucagc uccuguggca gaucgacagg gaaaugcuga     1860

accucuacau ugagaaugaa ggcaagauga ucaugcagga uaaacuggag aaggaacgca     1920

acgacgccaa gaaugcgguc gaggaguaug uguacgaaau gcgggauaaa uuguccgggg     1980

aguacgaaaa guuugugagc gaggacgaua ggaacaguuu cacccugaaa cucgaggaca     2040

cugaaaauug gcuguaugag gauggugaag accaaccaaa gcaggucuac guggauaaac     2100

uggccgaguu gaagaaccug ggccagccca uuaagauccg cuuccaggaa uccgaggagc     2160

ggcccaaacu cuuugaggag cuggggaagc aaauucagca guauaugaaa aucaucagcu     2220

ccuucaagaa uaaagaagac caauacgauc accucgacgc agccgauaug acgaagguag     2280

agaaaagcac caacgaagcc auggagugga ugaauaacaa gcugaacuug cagaauaagc     2340

agagucugac uauggaccca guggucaaaa gcaaggagau ugaagcaaaa aucaaggagc     2400

ucaccuccac uuguaguccc auuaucagca aaccaaagcc gaagguggaa cccccaaaag     2460

aggagcagaa gaacgccgaa caaaauggcc ccguggacgg ucagggcgau aacccagggc     2520

cccaggcggc cgagcagggc accgacacgg cagucccguc cgauagcgac aaaaagcugc     2580

cagaaaugga uauugacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  4505
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt7)

<400>  4505
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccuc aacugcuaca      120

uugccguggc aagguccggu ggcaucgaga ccauugccaa ugaauauagu gaucggugua      180

cucccgcgug caucagccug gggucccgca ccagggccau uggcaacgca gccaagaguc      240

agaucguaac gaaugugcgg aacacuaucc acgguuuuaa aaaguugcau gggcgcagcu      300

ucgacgaucc aauuguccaa accgagagga uccggcugcc guacgaacuc cagaaaaugc      360

ccaauggcuc cgcaggcgug aaggugcgcu aucuggagga agagaggcca uuugccauug      420

agcaggucac cgggauguug cuggcgaaac ucaaggaaac uagcgagaac gcccugaaga      480

aacccguggc agacugugua aucuccauuc caaguuucuu uaccgaugcc gaacggcgca      540

gcgugauggc cgcagcccag gucgcggguc ugaauugccu caggcugaug aacgagacga      600

cugccguggc auuggccuac ggcaucuaua agcaagaccu gcccccacuc gaugagaaac      660

cgcggaaugu ggucuucauu gacauggggc acuccgcaua ccaggugcug guaugugccu      720

uuaacaaggg caaacugaag guguuggcca ccacuuucga ucccuaucuc ggugggcgca      780

auuuugacga agcgcugguc gauuacuucu gcgacgaguu uaaaaccaag uacaagauca      840

acgugaaaga aaauagcagg gcacugcucc ggcuguauca ggagugugaa aaguugaaaa      900

agcugaugag ugccaacgcc uccgaucucc cacugaauau cgagugcuuc augaacgacc      960

uggacgugag cuccaaaaug aaccgcgcac aguucgagca auugugugcc agucuccugg     1020

cgagggucga acccccacug aaggccguga uggagcaggc aaaucuccag cgggaagaua     1080

uuagcuccau cgagauugua ggcggcgcca cccgcauccc cgcagugaag gaacagauua     1140

cgaaauuuuu ccugaaggac aucagcacua ccuugaacgc cgaugaggcc gucgcaaggg     1200

ggugcgcccu gcaaugcgcg auccucaguc cggccuuuaa agugcgggag uucuccauua     1260

cugaccuggu ccccuacagc aucacccuga gguggaagac caguuuugaa gaugguuccg     1320

gcgaguguga aguguucugc aaaaaucauc cagcacccuu uagcaaggug auuacuuucc     1380

acaagaaaga gccauuugaa uuggaggccu ucuauacgaa ccuccaugag guacccuacc     1440

cagacgcccg caucgggagc uuuaccauuc agaauguguu cccgcagucc gauggcgaca     1500

guagcaaggu caaagugaag guccggguga acauccacgg uaucuuuucc guggcaagcg     1560

cgaguguaau ugaaaaacaa aaucuggagg gcgaucacuc cgacgccccc auggaaacug     1620

agaccagcuu caagaacgag aauaaggaua acauggacaa aaugcaagug gaccaggaag     1680

aggggcauca gaagugucac gcagaacaua ccccagagga agagaucgau cacacuggcg     1740

ccaaaacgaa guccgccguc agugacaaac aggauaggcu gaaucagacc cucaagaaag     1800

ggaaggugaa guccauugac cugcccaucc aguccagcuu gugccgccag cugggucaag     1860

aucuccugaa caguuauauu gagaaugaag gcaaaaugau caugcaggac aagcuggaga     1920

aagaacggaa cgaugcaaag aaugccgucg aggaauacgu guaugacuuc agggaucgcu     1980

uggggacugu guacgagaaa uuuauuaccc cagaggaccu guccaagcuc agcgcgguac     2040

uggaagauac cgagaacugg cucuacgaag acggcgagga ucagcccaag caggucuaug     2100

uggacaaacu gcaagaauug aagaaauacg gucagccgau ccagaugaag uauauggagc     2160

acgaggaacg gccaaaagcc cugaacgacc ucggcaagaa gauccagcug gugaugaaag     2220

ucauugaggc auacaggaau aaggaugaac gguaugacca ucuggauccc acugagaugg     2280

agaaagugga aaaguguauc uccgacgcca ugaguugguu gaacagcaaa augaaugccc     2340

aaaacaagcu gucccucacg caggaucccg ugguaaaagu cagcgagauu guggcaaaga     2400

guaaggaacu ggacaauuuc ugcaacccaa ucauuuacaa acccaagcca aaagccgagg     2460

ugccggaaga uaagcccaaa gcgaauagcg agcacaacgg gccaauggac ggccagagcg     2520

ggaccgagac uaaguccgau agcaccaagg acaguagcca acauacuaaa uccaguggcg     2580

aaauggaggu cgauugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  4506
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt7)

<400>  4506
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugagcc ucguggccgc aaugcuguug cugcucuccg      120

ccgcgagggc cgaggaagag gacaaaaagg aagaugucgg caccguggua gggaucgacc      180

uggguacuac cuacaguugc gugggcgucu ucaaaaacgg gcggguggag auuaucgcaa      240

augaucaggg caaccgcauu acgcccagcu auguggccuu uacuccagaa ggugagaggu      300

ugaucgggga cgcagccaag aaucaacuga ccuccaaccc ggagaauacc gucuucgaug      360

cgaaacggcu cauuggccgc acuuggaacg accccagugu gcagcaggau aucaaguuuc      420

ugccauucaa gguaguggag aaaaagacca aacccuacau ccaggucgac auuggcgggg      480

gucaaacgaa gacuuuugcc ccagaagaaa ucagcgcaau ggugcugacc aaaaugaagg      540

agacugccga ggccuaucuc ggcaaaaagg ugacccacgc agucgugacc guacccgccu      600

acuucaauga ugcgcagagg caggccacga aggacgcagg gacuauugcc ggccugaacg      660

ugaugcggau cauuaaugaa ccaaccgcag ccgccaucgc guaugguuug gauaaacgcg      720

agggggaaaa gaacauucug gucuuugacc ucggcggcgg gacuuucgau gugucccugc      780

ugaccaucga caauggugug uuugaggucg uggcaaccaa cggcgacacu caucucgggg      840

gcgaagauuu cgaccagagg guaauggagc acuuuaucaa auuguacaag aaaaagacgg      900

guaaggaugu gcggaaagac aaucgcgccg uccaaaagcu gaggcgggag guggaaaaag      960

ccaagcgcgc acugagcucc cagcaucagg ccaggauuga gaucgaaagu uucuaugagg     1020

gcgaagauuu cagcgagacc cucacucggg cgaaauuuga ggaacugaac auggacuugu     1080

uccgcuccac caugaagccg guccagaagg ugcuggagga uagcgaccuc aaaaagagug     1140

auauugacga aaucgugcug guagggggcu ccaccaggau ucccaaaauc caacagcugg     1200

ugaaggaguu uuucaauggg aaagaaccaa gccgggguau caaccccgau gaggccgucg     1260

cauacggcgc cgcagugcag gccggggucu uguccggcga ccaagacacu ggugaucucg     1320

ugcugcugga cgugugucca cucacgcugg gcauugagac cguagggggc gugaugacua     1380

aguugauccc ccgcaacacc gucgugccga ccaagaaaag ucagauuuuu agcacugccu     1440

ccgauaauca gcccacgguc accaucaagg uguacgaagg ggagaggcca cugacuaaag     1500

acaaccaccu ccugggcacc uucgaucuga cugguauucc cccagcaccc cggggcgugc     1560

cacagaucga aguaaccuuu gagaucgacg ucaaugggau uuugagggug acggccgagg     1620

auaaggguac cggcaacaaa aauaagauca cuauuaccaa cgaccaaaau cgccucacuc     1680

cggaagagau cgaacggaug gugaacgaug cggagaaauu cgccgaagag gacaagaagc     1740

ugaaagagag gauugauacc cgcaaugaac uggagagcua ugcauacagu cucaagaacc     1800

agaucgggga caaagaaaag cugggcggga aauuguccag cgaggauaag gaaacgaugg     1860

agaaggccgu cgaggagaaa auugaauggc uggaaaguca ucaggacgcc gacaucgagg     1920

auuuuaaggc gaaaaagaaa gaacucgagg agaucgugca gcccauuauc uccaagcugu     1980

auggcagcgc agguccaccc ccaaccgggg aagaggacac ugccgaaaag gaugagcugu     2040

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  4507
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt7)

<400>  4507
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gggagcuggc agugggcauc gaccucggga      120

ccacuuacag cugcgucggu guguuccaac agggccgggu agaaauucug gccaacgauc      180

aggggaaucg caccacgcca uccuaugugg cguuuacuga caccgagagg uuggucggcg      240

augccgcaaa gagucaggcc gcacugaacc cgcacaauac cguguucgac gccaaacggc      300

ucaucggucg caaguuugcg gauacuaccg ugcaaagcga caugaaacau uggcccuuca      360

gggucguguc cgaagggggc aagccaaaag uacgggugug uuaccgcggc gaggauaaga      420

cguuuuaucc cgaagagauu aguagcaugg uccuguccaa gaugaaagag acugccgaag      480

cauacuuggg gcagccagug aagcacgccg ugaucaccgu ccccgccuau uucaacgaca      540

gccagaggca ggcaacuaaa gaugccggug cgauugccgg ccugaaugug cuccggauca      600

ucaacgagcc aaccgcagcc gcaauugccu acgggcugga ccgcaggggc gccggugaac      660

ggaauguacu gaucuuugau cucgggggcg gcaccuucga cguguccguc cugaguauug      720

augcgggggu guuugaggug aaggcaacgg ccggugacac ucauuugggc ggggaggacu      780

ucgauaaccg ccuggucaau cacuuuaugg aagaguucag gcggaaacau ggcaaggacc      840

ucagcgguaa caaacgcgcc cugaggcggc ugcgcaccgc augcgaaagg gccaagcgga      900

cuuuguccag caguacccaa gcgacccucg agaucgauuc ccuguucgaa ggcguggacu      960

uuuauacuag cauuacgagg gcccgcuucg aggagcugug uuccgaucuc uuucggagua     1020

cccuggaacc gguagagaag gcauugaggg acgccaaacu ggauaaggca cagauccacg     1080

acgugguccu cgucgggggc agcacucgca uucccaaagu gcagaagcug cugcaggauu     1140

ucuuuaaugg gaaagaauug aacaagucca ucaauccaga cgaggccgug gccuacggug     1200

cagccgugca agcggccgua cucaugggcg auaagugcga aaaagugcag gaccugcugc     1260

uccuggacgu cgcacccuug agccuggggc ucgagaccgc cggcggugug augaccacuc     1320

ugauccagcg gaacgccacg auuccaacca agcaaacuca gaccuucacc acuuacagug     1380

auaaucagcc cggcgucuuu auccaggugu augaggggga aagggcaaug acgaaagaca     1440

acaaccuguu gggccgcuuc gagcucuccg ggauuccgcc cgcgccacgg ggcgugcccc     1500

aaaucgaagu aaccuuugau auugacgcca augguauccu gagcgugacu gcaaccgaua     1560

ggaguacugg gaaggccaac aaaaucacca uuacgaauga caagggccgg cuguccaagg     1620

aggaagucga gcgcauggug cacgaggccg aacaguacaa agcagaggau gaagcccaga     1680

gggaccgggu cgcggccaag aacagccucg aggcacaugu guuccacgug aaagguagcc     1740

ugcaggagga auccuugcgc gauaagaucc cagaggaaga caggcggaaa augcaagaua     1800

agugucgcga gguacuggcc uggcucgaac auaaucagcu ggccgagaag gaggaauaug     1860

agcaccagaa aagggaacug gagcagauuu gccggcccau cuuuaguagg uuguacggcg     1920

ggccaggcgu ccccgggggc agcuccugug guacccaagc acgccagggg gacccgagca     1980

cuggcccaau uaucgaagag guggauugag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  4508
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt7)

<400>  4508
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gggagcuggc agugggcauc gaccucggga      120

ccacuuacag cugcgucggu guguuccaac agggccgggu agaaauucug gccaacgauc      180

aggggaaucg caccacgcca uccuaugugg cguuuacuga caccgagagg uuggucggcg      240

augccgcaaa gagucaggcc gcacugaacc cgcacaauac cguguucgac gccaaacggc      300

ucaucggucg caaguuugcg gauacuaccg ugcaaagcga caugaaacau uggcccuucc      360

aggucguguc cgaagggggc aagccaaaag uaagggugug uuaccggggc gaggauaaga      420

cguuuuaucc cgaagagauu aguagcaugg uccuguccaa gaugaaagag acugccgaag      480

cauacuuggg gcagccagug aagcacgccg ugaucaccgu ccccacuuau uucagcaacu      540

cccagcgcca agccaccaaa gacgcagggg ccauugcggg ccugaaggug cucccaauca      600

ucaaugaggc caccgcagcc gcaauugccu acgggcugga uaggcggggc gccgguaaac      660

gcaacguacu gaucuuugac cucgggggcg gcacguucga ugugaguguc cugagcauug      720

acgcgggggu guuugaagug aaggcaacug ccggugauac ccauuugggc ggggaggacu      780

ucgacaauag gcuggucaac cacuuuaugg aggaguuccg gcgcaaacau ggcaaggauc      840

ucuccgguaa uaagagggcc cugcggcgcc ugaggacugc augcgagcgg gccaaacgca      900

ccccgagcag uuccacccag gcgacuuugg aaaucgacag ccucuucgag ggcguggauu      960

uuuauaaguc cauuacgagg gcccgguucg aagaacugug uagugaccug uuuaggagca     1020

cccucgagcc cguagaaaaa gcacugcgcg augccaaguu ggacaaagca cagauccacg     1080

auuucgugcu ggguggcggg cuccacuccc auccacaggg ugccgagguc gccgcaggcc     1140

ugcugcaacg gcagggggcc gaacaggagc accaacccug aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  4509
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt7)

<400>  4509
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaagggcc ccgccguggg gaucgaccug gguaccacuu      120

acuccugcgu cggcguguuc cagcacggga aaguagagau uaucgcaaac gaucaaggca      180

auaggaccac gccaaguuau guggccuuua cugacaccga acggcucauu ggugaugcgg      240

ccaagaacca ggucgcaaug aauccgacca acacuguguu cgacgccaaa cgccugaucg      300

ggaggcgguu ugaugacgca gugguccaga gcgauaugaa gcauuggccc uucauggugg      360

uaaaugacgc cggccgccca aaagugcagg ucgaguacaa gggcgaaacc aaguccuuuu      420

aucccgagga agugaguagc augguguuga cgaaaaugaa ggagauugcg gaggccuacc      480

uggggaaaac ugucaccaac gcagugguaa cugugccagc cuauuucaau gauucccaaa      540

ggcaggccac caaggacgca gguaccaucg ccggccucaa cguccugcgg aucauuaaug      600

aacccacggc ggccgcaauc gccuacgggu uggauaaaaa ggugggcgca gagcgcaacg      660

ugcugauuuu ugaccucggu gggggcacuu ucgaugucag cauccugacc auugaagacg      720

gcaucuuuga ggugaaaucc acugccgggg acacccaccu ggguggcgag gauuucgaca      780

auaggauggu aaaccauuuu auugccgaau uuaagcggaa gcacaaaaag gauaucagug      840

agaauaaacg cgcggugagg cggcuccgca ccgcauguga aagggccaag cggacucuga      900

gcuccagcac gcaggccagu aucgagauug acuccuugua ugaagggauc gauuucuaca      960

ccagcauuac ucgcgcaagg uuugaggagc ugaacgccga ccucuuccgg ggcacccugg     1020

auccagucga aaaagcgcug cgcgacgcca aguuggauaa gucccagauc caugacauug     1080

ugcucgucgg uggcaguacc aggaucccga aaauccaaaa gcugcugcag gauuucuuca     1140

augggaaaga gcucaacaag agcauuaacc ccgacgaagc aguggccuac ggcgcagccg     1200

ugcaggccgc aauccugucc ggggacaaaa gcgagaaugu acaggauuug cugcuccugg     1260

acgugacucc acugaguuug gguauugaaa cggccggcgg ggucaugacc gugcucauca     1320

agcggaacac uaccauuccc accaagcaaa cucagacguu uaccacuuau uccgauaauc     1380

agccaggcgu ccugauccaa guguacgagg gugagagggc gaugaccaaa gacaacaauc     1440

ugcucggcaa guucgaacug acugggauuc ccccggcacc ccgcggcgug ccacagaucg     1500

agguaaccuu ugauaucgac gccaacggga uuuugaaugu gagcgccguc gauaaaagua     1560

cgggcaagga aaacaaaauc accauuacua augacaaggg ucggcugucc aaggaggaua     1620

ucgaaaggau ggugcaggag gccgagaaau auaaggcaga agacgagaaa cagcgcgaua     1680

aggucagcag caaaaacucc cucgaaaguu acgcguucaa uaugaaggcc accguggagg     1740

acgagaaacu gcaagggaag auuaacgaug aagacaagca gaaaauccug gacaagugca     1800

augagaucau uaacugguug gauaaaaauc agacugcaga aaaggaggaa uuugagcacc     1860

agcaaaaaga gcucgaaaag guguguaacc ccaucauuac caagcuguau cagagcgccg     1920

gcgguaugcc aggcgggaug cccggcgggu ucccaggcgg uggggccccg cccuccggcg     1980

gcgcaagcag ugggccaacg aucgaggaag uagacugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  4510
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt7)

<400>  4510
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucagcgccu ccagggcagc cgcggcccgg cuggugggcg      120

cagccgcaag ucgcgggccc accgccgcga ggcaccagga cagcuggaac ggucucuccc      180

augaggccuu ccggcugguc agucgcaggg auuacgcaag cgaagccauu aagggcgccg      240

ugguagggau cgacuugggc acuaccaauu ccugcguggc agucauggag gguaaacaag      300

ccaaggugcu ggaaaacgcg gagggggccc ggacgacucc aagcgugguc gcauuuaccg      360

ccgauggcga acgccucgug ggcaugccgg caaaaaggca ggccguaacc aaucccaaca      420

auacuuucua ugccaccaag cggcugauug ggcgcaggua cgacgaucca gaggugcaga      480

aagacaucaa gaacgucccc uuuaagauug ugcgggcguc caauggugau gcaugggugg      540

aggcccacgg caaauuguau aguccaagcc agaucggggc cuucguccug augaagauga      600

aagaaacggc agagaacuac cucggccaua cugccaagaa ugcggugauc accguacccg      660

ccuauuuuaa cgacucccaa cgccaggcaa cuaaagaugc cggucagauu agcgggcuga      720

augugcugag ggucaucaac gaaccaaccg cagccgcccu cgcauacggc cuggacaaga      780

gugaggauaa agugauugcc guguaugacu ugggcggggg uaccuucgau aucuccauuc      840

uggagaucca gaagggcguc uuugaaguaa agagcacgaa uggggacacu uuccucggcg      900

gugaggacuu ugaucaagcg cugcugcggc acauugugaa agaguucaag cgcgaaaccg      960

gcguggacuu gacuaaagau aacauggccc uccagagggu ccgggaagca gccgagaagg     1020

ccaaauguga gcuguccagu agcgugcaga ccgacaucaa ucugccguac cucaccaugg     1080

auuccagcgg gcccaagcau cugaacauga aguugacucg cgcacaguuu gaaggcaucg     1140

ucacggaccu gauuaggcgg accaucgcgc caugccaaaa agccaugcag gaugcagagg     1200

ugaguaaguc cgacauuggg gaagugaucc ucguaggugg caugacuagg augcccaaag     1260

ugcagcaaac cguccaggau cuguucgggc gcgccccaag caaggccgug aaccccgacg     1320

aggcagucgc cauuggcgcg gccauccagg guggcgugcu ggcaggggau gugaccgacg     1380

uauugcuccu ggacgugacu ccgcugaguc ucggcaucga aacgcugggc ggggucuuca     1440

ccaaauugau uaaucggaac acuaccaucc ccaccaagaa gucccaggug uuuagcacug     1500

ccgccgaugg ucaaacgcag gucgagauua aaguguguca gggggagagg gaaauggcag     1560

gcgacaauaa gcugcucggu caguucaccc ugaucggcau uccacccgcc ccacgcgggg     1620

ugccccaaau cgagguaacu uuugauaucg acgcgaacgg cauuguccac gugagcgcca     1680

aagauaaggg gaccggccgg gaacagcaga ucgugauuca guccaguggu gggcugagca     1740

aagacgauau cgagaauaug gucaagaacg cagaaaagua cgccgaggag gacaggcgca     1800

aaaaggaacg gguggaggca gugaauaugg ccgaaggcau uauccacgau acugagacca     1860

aaauggagga guucaaggac caauugccag cggaugaaug caacaaacuc aaggaagaga     1920

uuuccaaaau gagggaacug cuggcccgga aggacagcga gacgggcgag aauauccgcc     1980

aggcagccag uucccuccag caggccagcc ugaaguuguu ugaaauggca uauaaaaaga     2040

uggccuccga gagggaaggg agugguagcu ccggcaccgg ggagcaaaaa gaagaucaga     2100

aggaggagaa acagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  4511
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt7)

<400>  4511
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg aggcaggcgg gagcgauggu cccagggaaa      120

ccgccccaac uuccgcguac aguagcccgg cccggucccu gggcgacacc gggaucacgc      180

cccucagucc aagccacauu gugaacgaua cugacuccaa ugucagcgag cagcaauccu      240

uccugguggu aguggcaguc gauuuuggca ccaccaguag cgguuaugcc uacuccuuca      300

cuaaagaacc cgagugcauc caugugauga ggcgcuggga agggggcgac ccaggcguga      360

gcaaccagaa gacccccacg acuauuuugc ugaccccaga gcggaaauuu cacaguuucg      420

gguaugcagc ccgcgauuuu uaccaugacc ucgauccgaa ugaggcgaag caguggcugu      480

auuuggaaaa auucaagaug aagcugcaca cuaccgguga ccucaccaug gauacggacc      540

ugacugccgc aaacggcaaa aaggucaaag cccuggagau cuuugccuac gcacuccagu      600

auuucaagga acaagcccug aaagaguugu ccgaucaggc ggggagcgag uuugaaaauu      660

ccgacgugag guggguaauu accgugcccg ccaucuggaa gcagccagca aaacaguuca      720

ugcggcaagc cgcauaccag gccggccugg ccagucccga gaacagcgaa cagcucauca      780

uugcgcugga gccagaagca gccuccaucu acugucgcaa gcugagguug caucagauga      840

uugagcucag caguaaggcc gcagucaaug guuauuccgg gagcgacacu gugggcgccg      900

gcuuuaccca agcgaaagag cacauccggc gcaacaggca gagucggacc uuccuggugg      960

aaaaugucau uggggagauc ugguccgaac uggaggaagg ugauaaguac gugguagugg     1020

acagcggcgg gggcacuguc gaucucacgg ugcaccagau ucgccugccc gagggucauu     1080

ugaaagagcu guauaaggcc accggcgggc cguacggcag ccucggggug gacuaugagu     1140

ucgaaaaacu gcuguacaag aucuuuggug aagauuucau cgagcaauuu aagauuaaaa     1200

ggcccgcagc cugggucgac uugaugaucg cauucgaauc ccggaagcgc gccgccgcac     1260

cagauaggac uaacccccuc aauauuaccc ugccauuuag uuucaucgac uauuacaaaa     1320

aguuucgggg ccacagcgug gagcaugccc ugcgcaaauc caacguagau uucgugaagu     1380

ggagcaguca ggggaugcuc aggauguccc ccgacgcgau gaaugcccug uuuaagccaa     1440

ccauugauag caucaucgag cacuugcggg accuguucca gaaaccggaa gucuccacug     1500

ugaaguuucu cuuccugguc ggcgguuuug cagaggcacc ccuguugcag caagccgugc     1560

aggccgcguu cggcgaccag ugcaggauua ucauuccaca ggaugugggg cucacgaucc     1620

ugaaaggcgc cguacuguuc gggcucgacc ccgcagugau uaagguccgc cggaguccac     1680

ugaccuacgg cguggguguc uugaacaggu auguggaagg gaaacauccc ccggagaagc     1740

ugcucgugaa ggauggcacu cgcuggugua ccgacguauu ugauaaauuc aucagcgccg     1800

accaauccgu ggcccugggu gagcugguca agcggagcua caccccagca aaacccaguc     1860

aguuggugau cgucauuaau aucuauucca gcgaacacga uaacgugucc uuuauuacug     1920

accccggcgu gaagaaaugc gggacgcuga ggcucgaucu gaccggcacc agugggacug     1980

ccguaccagc gcgccgggag auccagacuc ucaugcaguu cggcgacacc gaaauuaagg     2040

ccacggcaau cgauauugcc accagcaaau ccgucaaggu ggguaucgac uuucugaacu     2100

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  4512
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt7)

<400>  4512
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuggccgugc ccgagauggg ccuccagggg cuguacaucg      120

guagcucccc agaaaggagu ccggucccca gcccacccgg cuccccacgg acccaagaga      180

guugcgggau ugcacccuug acuccaagcc aguccccgaa gcccgaagug cgcgccccac      240

agcaggcgag cuucuccgua guggucgcca ucgacuuugg caccacgagu agcgguuaug      300

cauucuccuu ugccagcgau cccgaggcaa uucacaugau gaggaaaugg gaagggggcg      360

acccaggcgu ggcccaucaa aagacuccca ccugucugcu ccugaccccg gagggggcgu      420

uccacaguuu ugguuacacu gcccgggauu auuaccauga cuuggauccc gaggaagcac      480

gcgacuggcu guauuucgag aaauuuaaga ugaaaaucca cuccgccacc gaucucacgc      540

ugaagacuca gcuggaagcc gugaacggca agaccaugcc agcacucgag gucuucgccc      600

augcgcugag guuuuuccgg gagcacgccu ugcaggaacu gcgcgagcag agccccuccc      660

ucccagaaaa agacacugug agguggguac ugaccgugcc cgcaauuugg aagcaaccag      720

ccaaacaguu uaugcgggag gcagccuacc uggccggguu ggucagucgc gaaaaugcgg      780

agcagcuccu gaucgcacug gagccggaag ccgccagcgu guauugcagg aagcuccggc      840

ugcaccaguu gcuggaucuc uccggccgcg cacccggugg gggcaggcug ggcgagcggc      900

gcagcaucga caguuccuuc aggcaagccc gggaacagcu gcgcaggagc cggcauagua      960

ggaccuucuu gguggagucc ggggucggug aacucugggc ggagaugcag gccggcgauc     1020

gcuacguggu agcagacugu gggggcggua cgguggaucu gacuguccac caacuggagc     1080

agccacaugg cacccucaaa gaacuguaca aggccagcgg gggccccuau ggggcagugg     1140

guguggacuu ggccuuugag cagcugcucu gccggauuuu cggcgaagac uuuaucgcca     1200

cuuucaaaag gcagcgccca gcagccuggg ucgaucugac cauugcguuu gaggcccgga     1260

agaggaccgc agggccccac cgcgccggcg cccugaacau cagcuugccg uucuccuuua     1320

uugacuucua ccggaagcaa aggggucaca auguggaaac ugcacuccgg cgcaguagcg     1380

uaaacuuugu gaaauggucc agccagggca ugcugaggau gaguugugag gcgaugaaug     1440

agcuguucca gccaacgguc uccgggauca uucagcauau cgaagcccuc cuggcacggc     1500

ccgaggugca aggcgucaag uugcuguuuc ucguaggggg cuucgccgaa agcgccgugc     1560

ugcagcacgc agugcaggcc gcgcugggug cccgcggguu gagggugguc gugccccaug     1620

augucggccu gaccauccuc aaaggugcag ugcuguuugg ccaggcccca ggggugguac     1680

gggugcgcag gaguccccuc acuuauggcg ucggggugcu gaaccgguuc gucccaggca     1740

ggcacccgcc cgagaaguug cuggugcgcg acggucggag guggugcacc gauguguucg     1800

agcgcuuugu agccgcagaa caauccgucg cccucgggga ggaagugcgg aggagcuacu     1860

guccagcgcg ccccggccag cggagggugc ugauuaaucu guauugcugu gccgcagagg     1920

acgcccgcuu caucaccgau ccaggcgucc ggaaaugcgg ggcauugucc cuggaacucg     1980

agcccgccga cugcggucag gauacugcgg gcgccccgcc agggaggcgc gagauucggg     2040

cagccaugca guuuggcgac acggaaauca aggugaccgc cguggaugua agcacuaaca     2100

ggaguguccg cgcauccauu gacuuccuga gcaauugagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  4513
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt7)

<400>  4513
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagggaga ugaccauccu gggcagcgca gugcucacuc      120

uguugcuggc cggguaccuc gcgcagcaau aucugcccuu gccaaccccg aaggucauug      180

guaucgaccu gggcacgacu uacugcuccg uggggguauu cuuucccggc accgguaaag      240

ugaaggucau uccagaugaa aacgggcaca ucaguauucc cagcauggug uccuucaccg      300

acaaugaugu guaugucggc uacgagagug uggaacucgc cgacagcaac ccacagaaua      360

cuaucuauga ugcaaaacgg uuuaucggca agauuuucac cgccgaggaa cuggaggcag      420

agaucgggcg cuaccccuuu aaaguacuga acaagaaugg uaugguggag uucuccguca      480

cgagcaacga aacuauuacc guguccccag aauauguggg caguaggcuc cuguugaagc      540

ugaaagagau ggccgaggcg uaccucggga ugccggucgc caaugcagug aucagcguac      600

ccgccgaauu ugaccugaag cagcggaacu ccacuauuga ggccgcaaau cuggccggcu      660

ugaaaauccu ccgcgugauu aacgaaccaa ccgcggccgc aauggccuac ggucugcaua      720

aggcagaugu cuuccacgug cuggugaucg accucggggg cggcacccug gaugucagcu      780

ugcugaauaa acaagggggu auguuucuca cgagggccau gaguggcaac aauaagcucg      840

ggggccagga cuucaaccag cggcuguugc aguaucucua caaacagauc uaucaaacuu      900

acgguuuugu gcccucccgc aaggaggaaa uucauaggcu gcggcaggcc guagagaugg      960

ugaagcugaa ucucacccug caccagagcg cgcaguuguc cguccugcuc acuguggagg     1020

aacaagaucg caaagagcca cauaguagcg acaccgaacu gcccaaggau aaacugucca     1080

gcgcagacga ccacaggguc aacaguggcu ucgggcgggg cuuguccgau aagaaaagcg     1140

gggagaguca ggugcuguuc gaaaccgaga ucucccgcaa gcuguuugac acucugaacg     1200

aggaucucuu ccagaagauu cuggugccga uccaacaggu auugaaagaa ggucaccugg     1260

agaagacgga aauugacgag gugguccucg ugggcgggag caccaggauc ccccggaucc     1320

gccaggucau ucaggaauuu uucggcaaag auccaaauac uagcguggac cccgaucugg     1380

ccgugguaac cgguguggcc auccaagcag gcauugacgg gggcuccugg ccacugcagg     1440

ucagugccuu ggagaucccc aacaagcauc ugcagaaaac caauuuuaac ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4514
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt7)

<400>  4514
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgcaaucg gcgugcaccu ggggugcacc agcgccugug      120

ucgcggugua caaggacggu agggccggcg uaguggcaaa cgaugccggg gaccggguca      180

cucccgcagu gguggccuau uccgagaaug aagagauugu cggccucgcg gccaaacaga      240

gucgcaucag gaacauuagc aauaccguga ugaagguaaa acaaauccug ggucggucca      300

guagcgaucc acaggcacag aaguacauug ccgaauccaa augcuuggug aucgagaaga      360

acgggaagcu gcgcuaugaa aucgacacgg gcgaggagac uaaauucguc aauccggaag      420

auguggccag gcucauuuuu agcaagauga aagagaccgc acauuccgug cugggcagug      480

acgccaacga ugucgugauc accguacccu ucgacuuugg ggaaaagcag aaaaaugcgu      540

ugggugaggc cgcacgggcc gcaggcuuca acgugcugcg ccucauucac gagccaagcg      600

ccgcccugcu ggcguacggg aucggccaag auucccccac ugguaagagc aauauucucg      660

ucuuuaaacu gggcgggacc aguuuguccc ugagcgugau ggaagugaac uccggcaucu      720

auaggguccu caguacgaau acugacgaua acauuggggg ugcacauuuc accgagacuc      780

uggcccagua ccuggccagc gaauuucagc gguccuucaa gcacgacgug cgcggcaaug      840

caagggccau gaugaaguug accaacagcg cggagguagc caaacauagu cucuccaccc      900

uggggagcgc aaauuguuuu cuggauaguc ucuaugaagg ccaggacuuc gacugcaacg      960

ugucccgggc ccgcuuugag cuguugugua gcccacuguu caacaagugc aucgaggcaa     1020

ucaggggucu ccuggaucaa aauggcuuca cggccgacga uauuaacaaa gucgugcugu     1080

gugggggcag cucccggauc cccaaguugc agcagcucau uaaagaccug uuuccagccg     1140

ucgaacugcu caauaguauc ccgcccgaug aggugauucc aaucggggca gccaucgaag     1200

cggguauucu gaucggcaag gagaacuugc ugguggaaga cagccucaug auugagugcu     1260

ccgcccgcga uauccuggua aagggggugg acgagagcgg cgcaaguagg uucacugucc     1320

uguuucccuc cgguacccca uugcccgccc ggcgccagca cacucuccaa gccccgggca     1380

gcauuuccag ugugugucug gaacuguacg agagcgaugg gaaaaauucc gcaaaggaag     1440

agaccaaauu cgcgcagguc gugcuccagg accuggauaa gaaagaaaac ggcuugaggg     1500

acauccuggc cgugcucacc augaagcggg acgggagccu gcacguaacu ugcacggauc     1560

aagagaccgg caagugcgag gcaaucagua uugaaaucgc cuccugagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  4515
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt7)

<400>  4515
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gccuggacgu ggggucccag aguugcuaca      120

ucgccguagc aagggccggu ggcauugaaa ccaucgcgaa cgaguucagc gaucggugua      180

cucccuccgu gauuaguuuu gggagcaaga aucgcaccau cggcgucgcc gccaaaaacc      240

aacagauuac gcacgcaaau aacacugugu ccaauuucaa gagguuucau ggucgggcau      300

ucaacgaccc auuuauccag aaagagaagg aaaaucucag cuaugaucug gugccguuga      360

aaaacggggg cgucggcauc aaggugaugu acauggggga ggaacaccug uucuccguag      420

agcagauuac cgccaugcuc cugaccaagu ugaaagagac ugcggaaaau agucugaaga      480

aacccgugac cgacugcguc aucagcgugc cauccuuuuu cacggaugcc gagcgcagga      540

gcgugcucga cgcagcccaa auugucgguc ugaacugucu gcggcucaug aaugauauga      600

cugccguggc acugaacuau ggcaucuaca agcaggacuu gcccagucug gaugaaaaac      660

cacgcauugu aguguuuguc gacauggggc auuccgccuu ccaggugagc gcgugcgccu      720

uuaauaaggg caaacucaag gugcugggua ccgcauucga ucccuuccug ggcgggaaga      780

acuuugacga gaaauugguc gagcacuucu gugccgaauu uaagacuaaa uauaagcucg      840

augcaaaauc caagaucagg gcccugcugc ggcucuacca ggagugcgaa aagcugaaaa      900

aguugaugag uagcaauucc accgaccugc cacucaacau ugaguguuuc augaacgaca      960

aagaugugag cggcaagaug aaucgcaguc aauuugaaga acugugcgcc gagcuguugc     1020

agaaaaucga aguaccgcuc uauucccugc uggagcagac ccaucucaag guggaagacg     1080

ucagcgcggu ggagaucguc gggggugcaa cgaggauucc cgccgugaag gaacggaucg     1140

ccaaauucuu uggcaaggau auuaguacua cccugaacgc agacgaggcc guggcgcgcg     1200

ggugugccuu gcagugcgca auccuguccc cagccuucaa aguaagggag uuuagcguga     1260

cugaugcagu ccccuuccca auuagccuca ucuggaauca cgacuccgaa gauaccgagg     1320

gcgugcacga agucuuuagu cggaaccaug ccgcccccuu cagcaaggug cugaccuuuc     1380

ugcgcagggg uccguucgag uuggaagcau ucuacuccga cccccaaggc gugccauacc     1440

ccgaggccaa aaucgggcgg uuuguagugc agaaugucag cgcgcagaag gauggcgaga     1500

agagucgcgu gaaagucaag gugaggguga acacucacgg gauuuucacg aucuccaccg     1560

ccagcauggu agaaaaaguc ccaacugagg aaaaugagau guccagugag gcagacaugg     1620

aaugccucaa ccaacggccc ccagagaauc cggauaccga caagaacgug cagcaggaca     1680

auagcgaagc cgguacccag ccccaagugc agacugaugc ccagcagacg ucccaaagcc     1740

cacccagucc agagcugacc uccgaagaga acaaaauucc cgacgcagau aaggcgaaug     1800

agaaaaaggu cgaccagccg ccagaagcca agaaacccaa gaucaaagug gugaacguag     1860

agcugcccau ugaagcaaau cucgucuggc agcugggcaa ggauuugcug aacauguaua     1920

ucgagacuga agggaaaaug aucaugcagg acaagcucga gaaggagagg aacgaugcca     1980

aaaaugccgu ggaagaguac guguaugaau uucgcgacaa gcuguguggc ccauacgaga     2040

aauucauuug cgaacaagau caucagaacu uucugcgguu gcugaccgag accgaggacu     2100

ggcucuauga agagggugaa gaucaggcaa agcaggccua cgucgacaaa cuggaggagc     2160

ucaugaagau cggcacuccc gugaagguaa gguuccaaga agcggaggaa cgcccaaaaa     2220

uguuugagga acuggggcag cgguugcagc acuaugccaa gauugcagcc gauuucagga     2280

auaaagacga gaaguacaac cacaucgacg agagcgaaau gaaaaaggug gagaaauccg     2340

ucaaugaagu gauggagugg augaacaaug ugaugaacgc ccaagcaaag aagagucugg     2400

aucaggaccc ggucgugcgc gcccaggaaa uuaaaacgaa gaucaaagag cucaauaaca     2460

ccugugagcc cguagugacu cagccaaagc ccaaaauuga aagcccaaag cuggagcgga     2520

cccccaaugg cccgaacauc gauaagaaag aagaggaccu ggaggauaag aauaacuuug     2580

gggcggaacc accccaucaa aauggcgagu gcuacccaaa cgagaaaaac uccgucaaua     2640

uggacuugga uugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  4516
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt7)

<400>  4516
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg ugaggcggca gcgccccagg cggcgcgucu      120

gcugggcacu gguggccgua cuccuggcgg auuugcuggc ccucagcgac acccuggcag      180

ugauguccgu cgauuugggc agugagagca ugaaaguggc caucgugaag ccaggggucc      240

cgauggaaau ugugcugaac aaagagucca ggcggaagac ucccguaauc gugacccuca      300

aagaaaauga gcgcuucuuu ggugacagug cagccagcau ggcgauuaag aacccaaagg      360

ccacgcugag guacuuccaa caucugcucg gcaaacaggc agauaauccc cacgucgccc      420

uguaucaggc ccgguuucca gaacacgagu ugacuuucga cccccagcgc caaaccgugc      480

auuuucagau cuccagccag cugcaguucu ccccagagga agugcucggg augguccuga      540

acuacaguag gagccuggca gaggauuuug ccgaacaacc gauuaaggac gcggugauca      600

ccguacccgu guucuuuaau caggccgagc ggcgcgcagu cuugcaggcc gcaaggaugg      660

ccggccucaa agugcugcag cugaucaacg auaauacugc caccgcgcuc uccuauggug      720

uguuccggcg caaggacauu aacacgacug cacaaaauau cauguuuuac gauaugggga      780

gcggcaguac cgucuguacu auugugaccu aucagauggu aaaaaccaag gaggccggca      840

ugcagccaca acugcagauc aggggugugg gguucgaccg gacguugggc gggcuggaaa      900

uggagcuccg ccugagggaa cggcuggccg gcuuguucaa cgagcagagg aaaggucagc      960

gcgcaaagga uguccgggaa aaucccaggg ccauggcgaa gcuccugcgc gaggccaacc     1020

ggcugaaaac ugugcucucc gcaaaugccg accacauggc acaaauugag gggcugaugg     1080

acgaugucga cuuuaaggcc aaagugacca ggguggaguu cgaggaauug ugcgccgauc     1140

uguuugagcg cguaccaggc cccgugcagc aggcacucca gagcgccgaa augucccugg     1200

acgagaucga gcaagucauu cuggugggcg gggcgacucg ggucccgagg gugcaggaag     1260

uguugcucaa ggccguaggu aaagaggaac ugggcaagaa caucaaugca gaugaggccg     1320

ccgcaauggg ggcgguguac caggccgcag cccugaguaa ggccuucaaa gucaagcccu     1380

uugugguccg ggacgcagug guguauccaa uccucguaga guucacccgc gaggucgagg     1440

aagaacccgg cauucauagc cugaaacaca acaagagggu guuguuuucc cggauggguc     1500

cauaccccca gcgcaaagug aucaccuuca acagguacag ccacgauuuu aauuuccaua     1560

uuaacuaugg cgaccugggg uuucucggcc cagaagaucu gcgggucuuc gggagucaaa     1620

aucugacuac ggugaaguug aagggugugg gcgacuccuu uaaaaaguac ccggauuaug     1680

agagcaaagg gaucaaggcc cacuucaacc uggacgagag uggcguacuc ucccuggacc     1740

gcgucgaaag cguguucgag acccucgugg aagauagcgc ggaggaagag uccacucuga     1800

ccaaauuggg uaauaccauu aguagccugu uuggcggggg cacuacgccc gacgccaagg     1860

agaacgggac cgauacuguc caggaagagg aagagucccc agcagaaggc agcaaggacg     1920

agcccgguga acagguggaa cucaaagagg aagccgaggc cccaguagaa gaugggaguc     1980

agcccccgcc acccgagccc aagggcgacg caaccccaga gggugaaaaa gccaccgaga     2040

aggaaaaugg cgauaaaucc gaggcgcaaa agcccagcga gaaagccgaa gcagggccag     2100

agggcguggc cccggcaccc gaaggggaga agaagcagaa accagccagg aagcggagga     2160

uggucgaaga gaucggcgug gagcuggugg uccuggacuu gcccgaucug ccagaagaca     2220

aacucgcgca guccgugcaa aagcugcagg aucucacucu gcgcgacuug gagaaacagg     2280

aacgggagaa ggccgcaaac agucuggaag ccuucaucuu ugagacgcag gauaagcugu     2340

accaacccga guaucaggaa guaagcaccg aggaacagag ggaggagauu uccgguaaac     2400

ucagcgccgc aaguacuugg cuggaagacg aggggguggg cgccaccacu gucauguuga     2460

aggaaaaacu ggcggagcuc cgcaagcugu gucagggccu cuucuuucgg guggaagaga     2520

ggaaaaagug gccggagcgc cuguccgccu uggacaaucu gcugaaccau agcuccaugu     2580

uccucaaggg ggcacggcug aucccagaaa uggaucaaau uuuuaccgag guggaaauga     2640

cgaccuugga gaaagucauc aaugaaacuu gggccuggaa gaacgcaacc cuggccgagc     2700

aggccaaacu ccccgcaacu gagaagccag ugcugcugag uaaagacauu gaagcgaaga     2760

ugauggcccu cgauagggag guacaguacc uguugaauaa agccaaguuc accaagcccc     2820

gcccgcggcc caaagacaag aacgguacga gggcagaacc accccugaau gccagcgcau     2880

ccgaucaggg cgagaaagug aucccacccg ccgggcaaac cgaagacgcg gagccaauca     2940

gcgagccgga aaaggucgag acuggcagug aacccgguga uaccgagcca cucgagcugg     3000

gcgggcccgg cgccgaacca gagcagaaag aacaguccac ugggcaaaag cgccccuuga     3060

agaacgacga gcugugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4517
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt7)

<400>  4517
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaaa cccagacuca agaccagcca auggaggaag      120

aggaagugga gaccuucgcc uuucaggcag agaucgccca gcugaugagc cucauuauca      180

acacguucua cuccaauaag gaaauuuuuc ugagggaguu gaucaguaac agcuccgaug      240

cgcuggacaa aauucgguau gaaagucuca cugauccgag caagcuggac uccggcaaag      300

aguugcacau caaucugauc cccaacaagc aagaucgcac ccucaccauu gucgacacug      360

ggaucgguau gaccaaagcc gaucugauua auaaccuggg cacgaucgca aagagcggga      420

cuaaggccuu cauggaggca cuccaggccg gcgcggacau uuccaugauc ggucaguuug      480

gggugggcuu cuacagugcc uaucugguag cagaaaaagu gaccgucauu acuaagcaua      540

augaugacga gcaguacgcc ugggaaagcu ccgccggcgg gagcuuuacc gugaggaccg      600

auacggguga gccaaugggc cgggggacua aagugaucuu gcaccugaag gaagaccaaa      660

ccgaguaucu cgaggaacgc aggaucaaag agauugucaa gaaacauagu caguucaucg      720

gcuaccccau uacucuguuu guggaaaagg agcgggauaa ggaaguaucc gacgacgagg      780

cagaggaaaa agaggauaag gaagaggaaa aagagaagga ggaaaaagag agcgaagaca      840

agccagagau cgaggaugug gguuccgacg aagaggaaga gaagaaagau ggggacaaga      900

aaaagaaaaa gaagauuaaa gaaaaguaua ucgaucagga ggagcugaac aaaaccaagc      960

ccaucuggac ccgcaaucca gacgauauua cuaacgaaga guacggcgag uucuacaaaa     1020

guuugacgaa ugacugggag gaucaccucg ccgucaagca uuuuagcgug gaaggccagc     1080

uggaguucag ggcgcuccug uucgugccgc ggcgcgcccc cuuugaccug uucgagaaca     1140

ggaagaaaaa gaauaacauc aaauuguaug uccggcgcgu guuuauuaug gacaauugcg     1200

aagaacugau cccagaauac cucaacuuca uuaggggugu aguggauucc gaggaccugc     1260

cccugaacau cagccgggaa auguugcaac agaguaagau ccucaaaguc auucgcaaga     1320

aucuggugaa aaagugucug gagcucuuua ccgagcuggc agaagauaag gagaacuaua     1380

aaaaguucua cgaacaguuu uccaaaaaua ucaaguuggg gauucacgag gacagccaaa     1440

acaggaaaaa gcugagugag cuccugcggu auuacacuuc cgccagcggc gaugaaaugg     1500

ugagccugaa ggacuauugc acccgcauga aagagaauca gaagcacauc uacuacauua     1560

ccggggaaac uaaagaucag gucgcaaacu ccgccuucgu ggagagguug cggaagcaug     1620

gccucgaagu aaucuauaug auugagccaa ucgacgagua cugugugcag caacugaaag     1680

aauuugaggg uaagacgcug gucaguguga ccaaggaagg ccucgagcug cccgaagaug     1740

aggaggagaa aaagaaacag gaagaaaaga aaacuaaguu cgagaauuug ugcaaaauca     1800

ugaaggacau ucuggagaag aaagucgaaa aggugguggu aagcaacagg cucgugaccu     1860

ccccguguug caucgucacc agcacuuaug gguggacggc caauauggag cgcauuauga     1920

aagcgcaggc acugcgggau aacaguacca ugggcuacau ggccgccaag aaacaccugg     1980

aaaucaaucc cgaccauucc auuaucgaga cuuugaggca gaaggcagaa gccgauaaga     2040

acgacaaaag cgugaaggac cuggucaucc uccuguauga gaccgcgcuc cuguccagug     2100

gguuuagcuu ggaggaucca caaacucacg ccaaucgcau uuaccggaug aucaaacugg     2160

gucucggcau ugacgaagau gaccccaccg cagaugacac guccgccgca gugaccgagg     2220

aaaugccacc ccuggagggg gaugacgaua cuagcaggau ggaagaggug gacugaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  4518
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt7)

<400>  4518
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucca agcuggauag uggcaaaggg cuccacauca      120

accuggugcc caauaagcag aaccaaaccu ugacuauugu cgacaccagg aucgguauga      180

cgaaaacuga ucugauuaau aaccucggca ccgugaccaa gagcgggacu aaagccuuca      240

uggaggcacu gcaggccgac gcggauaucu ccaugauugg ccauuuuggu guaggguucu      300

acagugccua uuugguggca aagaagguca ccgugaucag caaacacaau aacgacgaac      360

aguacacgug ggaguccagc gccggcggcu ccuuuacugu gcggaccgau gaaugaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  4519
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt7)

<400>  4519
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaag ugcaccaugg cgaggaagag gucgaaaccu      120

ucgccuuuca ggcagagauc gcccaacuga ugagccucau uaucaacacu uucuacucca      180

auaaggagau uuuucugagg gaauugauca guaacgcgag cgacgcccug gauaaaauuc      240

gguaugaguc ccucaccgac ccaaguaagc uggauagcgg gaaagaauug aagaucgaca      300

ucauuccgaa uccccaggag cgcacgcuga cucucgugga uaccgguauc ggcaugacca      360

aagcagaccu gauuaacaau cuggggacua ucgccaaguc cggcaccaag gcauucaugg      420

aggcccucca ggcgggugcc gauauuagca ugaucgggca guuuggcgua ggcuucuacu      480

ccgcauaucu gguggccgaa aaagucgugg ugauuacgaa gcacaacgac gaugagcaau      540

acgccuggga aaguagcgca ggggguuccu uuacugucag ggccgaccau ggcgagccaa      600

ucgggcgggg caccaaagug aucuugcacc ugaaggaaga ucagacugag uaucucgagg      660

aacgcagggu aaaagaggug gucaagaaac auagccaguu cauugguuac cccaucaccc      720

uguaucugga aaaggagcgg gaaaaggaga uuagugacga ugaggcggaa gaggaaaaag      780

gggagaagga agaggaggac aaagacgaug aagagaagcc aaaaaucgaa gacgugggcu      840

ccgaugagga ggacgauagc ggcaaggaca agaaaaagaa aaccaagaaa auuaaggaaa      900

aguacaucga ucaggaggaa uugaauaaaa cgaagcccau cuggacucgc aacccagacg      960

auauuaccca agaggaauac ggggaguuuu auaaaucccu cacuaaugac ugggaggauc     1020

accuggccgu gaagcacuuc agugucgaag gucagcugga guuuagggca cuccuguuca     1080

ucccgcggcg cgcccccuuc gacuuguuug aaaacaaaaa gaagaaaaau aacauuaagc     1140

uguacgugag gcggguauuc aucauggaca gcugcgauga gcucauucca gaauaucuga     1200

auuuuauccg cggcgugguc gacuccgagg aucugcccuu gaacaucagc agggagaugc     1260

uccagcagag uaaaauucug aaggugaucc ggaaaaauau ugugaagaaa ugucuggaac     1320

ucuucuccga gcuggcagaa gacaaggaga acuacaagaa auuuuaugaa gccuucagca     1380

agaacuugaa acuggggauc caugaggaua guaccaaucg caggcggcuc uccgagcugc     1440

ugcgcuacca caccagccaa agcggcgacg aaaugacuuc cuugagugag uaugucagca     1500

ggaugaagga aacgcagaaa uccauuuacu acaucaccgg ugagagcaag gaacaggugg     1560

ccaacagugc guuuguagag cgggugagga agcgcggcuu cgaggucgug uauaugacug     1620

aaccaauuga ugaguacugc guccaacagc ucaaagaauu ugacgggaag ucccugguga     1680

gcgugaccaa agagggccug gagcuccccg aagaugagga agagaagaaa aagauggaag     1740

aguccaaggc aaaauucgag aaucugugua aguugaugaa agaaauccug gacaagaaag     1800

uagagaaggu gaccaucagu aaccggcucg ucagcucccc gugcuguauu gugacuagca     1860

cguaugggug gaccgccaau auggaaagga ucaugaaagc ccaggcacug cgcgauaaca     1920

guacuauggg uuacaugaug gccaagaagc aucuggagau uaaucccgac cacccaaucg     1980

ucgagaccuu gcggcagaaa gcggaagccg auaagaacga caaagcagug aaggaccugg     2040

ugguacuccu guuugagacc gcccuccugu ccagcggcuu cuccuuggaa gauccccaaa     2100

cucacaguaa uaggauuuau cgcaugauca aacuggggcu cggcaucgac gaggaugaag     2160

uggcagccga ggagccaaac gccgcagucc ccgacgaaau uccaccgcug gagggugaug     2220

aagacgccag ccggauggag gaaguggauu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  4520
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt7)

<400>  4520
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agggcccugu gggugcucgg ccugugcugu gucuugcuga      120

ccuucgggag cgugcgggca gacgaugagg uagacgugga ugguacuguc gaagaggacc      180

ucggcaaguc ccgcgaaggg aguaggaccg augacgaggu ggugcagcgg gaagaggagg      240

ccauccaacu ggauggcuug aacgcgagcc agauucgcga acugagggag aaauccgaaa      300

aguuugccuu ccaggcagag gucaaucgga ugaugaaacu caucauuaac agucuguaca      360

agaauaaaga gaucuuucug cgcgaacuca uuagcaacgc cuccgacgca cuggauaaga      420

ucagguugau cagccugacg gacgagaaug cccucuccgg uaacgaagaa cugacuguga      480

agauuaaaug cgauaaggag aaaaaucugu ugcacguaac cgacaccggg gugggcauga      540

cucgggagga gcucgucaag aaccugggca ccaucgcgaa aagugggacg agcgaguucc      600

ugaauaagau gacugaggcc caggaagaug gucaauccac cagcgagcuc auuggccagu      660

uugggguggg cuucuauagu gcauuucugg uggccgacaa agucaucgug acuuccaagc      720

auaacaauga cacccagcac auuugggaaa gcgauuccaa cgaguucagu guaaucgccg      780

acccccgcgg uaauaccuug gggaggggca cgacuauuac ccuggugcuc aaggaggaag      840

caagcgauua ccuggagcug gacacuauca aaaacuuggu caagaaauau ucccaguuua      900

ucaauuuccc aauuuacgug uggagcagua agaccgaaac cguggaggaa ccgauggagg      960

aggaagaggc cgcgaaagaa gagaaggagg aauccgauga cgaggccgca gucgaagagg     1020

aagaggagga aaagaaaccc aagacuaaaa agguggagaa aacgguaugg gauugggaac     1080

ucaugaacga caucaagcca auuuggcaac ggcccagcaa ggagguggaa gaggaugagu     1140

auaaagccuu uuacaagagu uucuccaaag aaagcgacga uccaauggca uauauccauu     1200

ucaccgccga gggcgaaguc acuuuuaaga gcauucuguu cgugcccacc uccgccccac     1260

gcgggcuguu ugacgaguac gguaguaaaa agagcgacua caucaagcuc uaugucaggc     1320

ggguguucau caccgaugac uuucacgaua ugaugccgaa auaccugaac uucgugaagg     1380

gcguagugga cuccgaugac uugccccuga augucagccg cgaaacucuc cagcagcaua     1440

aacugcugaa ggugauuagg aaaaaguugg uccggaaaac gcucgauaug aucaagaaga     1500

uugcggacga uaaauauaac gacaccuuuu ggaaggaguu cgggacuaau aucaaacugg     1560

gcgugauuga ggaucacagu aaccgcacca ggcuggcaaa gcuccugcgg uuucagucca     1620

gccaccaucc aaccgacauc acuuccuugg aucaauacgu ggaaaggaug aaagagaagc     1680

aggacaagau cuauuucaug gccgguagua gccgcaaaga agccgagucc agccccuuug     1740

uagagcggcu gcucaagaaa ggcuacgaag ugauuuaucu gacggagcca gucgacgaau     1800

acuguaucca ggcacugccc gaguucgaug ggaagagguu ucaaaaugug gccaaagaag     1860

gcgucaaguu cgacgagagu gagaagacca aagaaucccg cgaggcggug gaaaaggagu     1920

ucgaaccguu gcugaacugg augaaagaua aggcccucaa agacaagauu gagaaagcag     1980

ugguaagcca gcggcugacu gagucccccu gcgcccucgu cgcaagucag uacgggugga     2040

gcgguaauau ggaaaggauc augaaggccc aggccuauca aaccggcaag gauauuucca     2100

cuaacuacua ugcaagccag aaaaagaccu uugagaucaa uccacgccac ccccugauuc     2160

gggacauguu gaggcggauc aaagaagaug aggacgauaa gacggugcug gaccucgccg     2220

ugguccuguu cgagaccgcg acucugcgca guggguacuu gcugccagau accaaagccu     2280

auggcgacag gaucgaacgg augcuccgcc ugucccucaa cauugacccc gaugcaaagg     2340

uggaggaaga accagaagag gagccggaag agacugccga agacaccacg gaggauaccg     2400

aacaggacga ggaugaggaa auggacgugg guacugauga ggaagaggaa accgccaagg     2460

agagcacugc agagaaagac gaacugugag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  4521
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt7)

<400>  4521
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagggagc ugcgggcacu ccuguugugg ggccgcaggc      120

ugcggccccu ccugcgcgcc ccagcguugg ccgcagugcc cggggguaag ccgauccugu      180

gcccaaggcg gaccacugcc cagcucggcc cccgcaggaa cccagcaugg agccugcaag      240

ccgggcggcu guucuccacc cagacggcgg aagacaaaga ggaaccccuc cacaguauua      300

ucagcuccac ugagaguguc cagggcagca ccuccaagca ugaauuucag gccgagacca      360

aaaagcuguu ggauauugug gcacgcagcc uguacuccga gaaagaagua uucaucaggg      420

agcucauuag uaaugccagc gacgcccugg aaaagcugcg gcacaaguug guguccgaug      480

gucaagcacu cccagagaug gagauccauc ugcagacuaa cgccgaaaaa gggaccauca      540

cgauucagga cacuggcauc ggcaugaccc aggaggaacu ggucagcaau cucgggacua      600

uugcgcgcag ugguuccaag gccuuucugg augcauugca aaaccaggcc gaggcaagcu      660

ccaaaaucau uggccaguuc ggggugggcu uuuauagugc cuucauggug gccgacaggg      720

ucgaagugua cagccggucc gcggcaccgg guagccuggg guaucagugg cucagugaug      780

gcuccggcgu auuugagauc gccgaggcca gcggggugcg caccgguacc aagauuauca      840

uccaccugaa aagugacugu aaggaguucu ccagcgaggc aaggguccgg gaugugguga      900

cgaaauacag caauuuuguc uccuuccccc uguauuugaa cggccgcagg augaauacuc      960

uccaagccau uuggaugaug gacccaaagg augugcggga auggcagcau gaggaauuuu     1020

acagguaugu agcgcaggcc cacgacaagc cccgcuacac ccugcacuac aaaacugaug     1080

caccacugaa cauccggagu auuuucuaug ugcccgacau gaagccgagc auguucgacg     1140

ucuccaggga gcucgggagc aguguggccc uguacucccg caaaguguug auccaaacca     1200

aggcaaccga uauucugccc aaauggcucc gguuuaucag gggcgucgug gacagcgagg     1260

auaucccacu gaaucugucc cgcgaauugc uccaggagag ugcccugauu cggaagcuga     1320

gggacguacu ccagcagcgg cugaucaagu ucuuuauuga ucaaagcaaa aaggacgccg     1380

aaaaauaugc aaaguucuuu gaggauuacg guuuguucau gcgcgaaggc aucgugacug     1440

ccacggagca ggaggucaaa gaagacauug cgaagcugcu cagguaugag uccagcgccc     1500

ugcccagugg gcagcugacc uccuugagcg aauacgcauc ccggaugcgc gccggcacua     1560

ggaacaucua uuaccugugc gccccaaauc ggcaucucgc agagcacagu cccuacuaug     1620

aggcgaugaa gaaaaaggau accgaagugc uguuuuguuu cgagcaguuu gacgaacuca     1680

cccuguugca ucugcgcgag uucgauaaaa agaaacucau cagcgucgaa acugacauug     1740

ugguggacca cuacaaggag gagaaguuug aagauagguc cccagccgca gagugccuga     1800

gcgaaaaaga gacggaagaa cugauggccu ggaugcggaa cguauugggg aguaggguga     1860

ccaaugucaa ggugacucug cgccucgaca cccacccggc cauggucacc gugcuggaga     1920

ugggugcagc ccggcauuuc cucaggaugc aacagcuggc gaaaacucag gaggaacgcg     1980

cccaguugcu gcaacccacg cuggaaauca acccacggca cgcacucauu aagaaacuga     2040

aucaguugag ggccuccgag cccggccugg cccagcuccu gguggaucag aucuaugaaa     2100

acgcaaugau ugccgcgggg cucguagacg auccacgcgc cauggugggc cggcugaacg     2160

aguugcuggu caaggcacug gagaggcauu gaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  4522
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt7)

<400>  4522
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagauca gcucccugcc cacccaacuc uucaaaugcu      120

guuuuugcga cuuccugaag gugaaaaugc acacuaugag uagcucccau uuguuuuacc      180

uggcccucug ucuguugacc uucacgagua gcgcaacugc cgggccagag acccugugcg      240

gugcggaacu cgucgaugcc cugcaguuug uguguggcga caggggguuc uauuuuaaca      300

agccgaccgg cuacgguucc agcucccggc gcgcacccca gacugggauu guagaugagu      360

gcuguuucag gaguugcgac cugcggcgcc ucgaaaugua uugugcccca cugaaacccg      420

caaagagcgc cagguccgug cgggcgcagc gccacaccga uaugccaaag acgcagaaag      480

agguccauuu gaagaaugcc agcaggggca gugcaggcaa caaaaauuac cggaugugag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  4523
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt7)

<400>  4523
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca uggguaagag caugcuggug cuccugaccu      120

ucuuggccuu ugcauccugc uguauugccg cguacaggcc aagugagacu cugugcgggg      180

gcgaacucgu cgacacccug caguucgugu guggggaucg gggcuuuuau uucagccgcc      240

cggccuccag gguaagucgg cgcagcaggg guaucgugga ggaaugcugu uuucgguccu      300

gcgacuuggc acugcucgag acguacugug ccacucccgc aaaaagcgaa cgcgaugucu      360

ccaccccacc caccgugcug ccagacaacu uccccaggua uccagugggg aaguuuuucc      420

aauacgauac uuggaaacag aguacccagc ggcugcgcag gggccucccg gcccuguugc      480

gggcgcgcag gggccacguc cuggccaagg agcucgaggc auuucgggaa gccaaacgcc      540

auaggccccu gauugcccug ccaacgcagg accccgcaca cgggggugcc ccacccgaga      600

uggcgagcaa ucggaaguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  4524
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt7)

<400>  4524
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagcuucu ccaccagugc cuuuggcccc guggcauuca      120

gccuggggcu ccuguugguc cugccagccg cguuuccggc ccccgugcca cccggugagg      180

acuccaagga uguagcagcc ccacacaggc agccccucac caguagcgaa cggaucgaca      240

aacaaauucg cuacauccug gauggcauuu ccgcauugag gaaggagacu ugcaauaaaa      300

gcaacaugug ugaauccagu aaggaggccc uggcggaaaa uaaccucaau cugccaaaaa      360

uggccgagaa ggacgggugc uuccagagcg gcuuuaacga ggaaacgugu cuggugaaga      420

ucauuacugg ucuccuggag uucgaagucu auuuggagua ccugcagaau cgguuugagu      480

ccagcgaaga acaggcacgc gccgugcaaa ugaguaccaa agugcucauc caguuccugc      540

agaagaaagc caagaaccug gaugcaauca ccacuccgga ccccaccacg aaugccuccu      600

ugcucacuaa acugcaggcg caaaaccagu ggcugcagga uaugaccacu caucucauuc      660

ugaggagcuu uaaggaguuc uugcagucca gucugcgggc ccuccgccaa augugaggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  4525
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt7)

<400>  4525
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcucu ggcugagggg cuucuugcug gccagcugcu      120

ggaucauugu gcgguccagu ccaaccccgg ggagcgaggg ucacuccgca gcccccgacu      180

guccaaguug cgcgcucgcc gcacugccca aggauguccc aaacagccag cccgaaaugg      240

uggaggccgu gaaaaagcau aucuugaaua ugcugcaccu caaaaagcgc ccagacguaa      300

cucaaccggu ccccaaagca gcccugcuga acgcgauuag gaagcuccau gugggcaagg      360

ugggggaaaa uggcuacguc gagaucgaag augacauugg ucggcgcgcc gagaugaacg      420

agcugaugga acagaccucc gagaucauca cguuugcaga aagcgggacu gccaggaaaa      480

ccuugcacuu cgagauuucc aaggagggca gugaucugag cgugguagaa cgggccgagg      540

uguggcucuu ucugaaaguc ccaaaggcaa aucgcaccag gacuaaagug accauccggc      600

uguuccagca gcaaaagcau ccccagggcu ccuuggacac gggggaagag gccgaagagg      660

ugggucucaa aggcgagcgc agcgaacugc ugcucaguga gaaggucgug gaugcgagga      720

aguccacuug gcacguauuu ccagugagcu ccaguauuca gcggcuguug gaccagggga      780

aaagcucccu ggauguccgc aucgccugug aacaaugcca ggagagcggc gcaagucucg      840

ugcugcuggg uaagaaaaag aaaaaggaag aggaggggga aggcaagaaa aagggcgggg      900

gugagggcgg ggccggcgca gacgaagaga aagaacaguc ccacaggccc uucuugaugc      960

uccaggcccg gcaaagcgag gaucauccgc accgcaggcg gcgcaggggu cuggagugug     1020

acggcaaggu gaacauuugc uguaaaaagc aguuuuucgu caguuuuaag gauaucgggu     1080

ggaaugacug gauuaucgcc cccuccggcu aucaugcgaa cuacugcgaa ggggaguguc     1140

caagccacau cgcagguacc agcggcucca gucugagcuu ccacuccacu gugauuaauc     1200

auuaucggau gagggggcac agccccuuug ccaaccucaa aaguugcugc guaccaacca     1260

agcugcgccc cauguccaug uuguacuaug acgauggcca gaauaucauu aaaaaggaca     1320

uccaaaacau gauuguggaa gagugugguu gcagcugagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  4526
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt7)

<400>  4526
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccugc ccgggagggc ccucggugca gccugccugu      120

ugcugcucgc ggccggcugg cuggggccag aggcaugggg cagcccgacu cccccaccca      180

ccccagccgc acccccaccg cccccacccc cagguucccc cgggggcagu caggauaccu      240

guacgagcug cggcggguuc cggcgcccgg aagaguuggg uaggguggac ggcgauuuuc      300

uggaagccgu caagcggcac auccucuccc gccugcaaau gagggggcgg cccaacauua      360

cucaugcggu gccaaaagcc gcaaugguaa ccgcccugcg caagcuccac gccggcaaag      420

ugagggagga cggucggguc gaaauccccc aucuggaugg gcacgcaagu ccaggcgccg      480

acggccagga gcgcgugagc gagauuaucu ccuucgcgga aaccgauggg uuggccagcu      540

ccagggugcg gcuguacuuu uucauuagua augaggguaa ccagaaucuc uuugucgugc      600

aggcaagccu guggcuguau uugaagcucc ugcccuacgu acuggaaaaa ggcucccgca      660

ggaaggugcg ggucaaggug uauuuccaag agcaggggca uggcgaccgc uggaacaugg      720

uggagaaaag ggucgaucuc aagcggagcg guuggcacac uuuuccacug accgaagcca      780

uccaggcauu guucgagcgc ggcgaaaggc ggcugaaucu cgacgugcag ugugauaguu      840

gccaagagcu ggccguagug ccggucuuug uggaccccgg ggaagagucc cacaggccau      900

ucguggucgu gcaggcccgc cugggcgaua gccggcauag gauccgcaaa cggggguugg      960

agugugacgg uaggacgaac cucugcuguc gccagcaguu uuucauugac uuccggcuga     1020

ucggcuggaa ugauuggauu aucgcgccca cuggguacua uggcaacuac ugcgaagguu     1080

ccuguccagc auaucuggcc ggcguacccg ggagugccag cuccuuucac accgcagugg     1140

ucaaucaaua caggaugcgg ggccucaacc cggggacugu gaauagcugc ugcauuccaa     1200

ccaagcugag uaccaugucc auguuguacu ucgacgauga guauaacauc gucaaacgcg     1260

acgugcccaa uaugauugug gaagagugug gcugcgccug aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  4527
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt7)

<400>  4527
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugaggg ugcuccuguu gaccgcacug acucucugcc      120

acggcuucaa ccuggacacc gagaaugcca ugacguuuca ggaaaacgcg cggggguucg      180

gucaaagcgu cgugcaguug cagggcuccc gcguaguggu cggggcgccc caggagaucg      240

uggcagccaa ucaaaggggc agucuguacc agugugauua uagcacuggu uccugcgaac      300

caauucggcu ccaggugccg gucgaggcag ugaacaugag ucuggggcug agccucgccg      360

cgaccaccuc cccaccccag cuguuggccu guggccccac uguacaucaa accugcagcg      420

aaaauacgua cgugaagggc cuguguuuuc ucuucggguc caaccugcgc cagcagccac      480

agaaauuucc cgaggcacug agggguugcc cacaagagga cagugauauc gccuucuuga      540

uugacggcag cggguccauc auuccgcacg auuuucggcg caugaaggag uucgucagca      600

cugugaugga acagcucaaa aagaguaaaa cccuguuuuc ccugaugcag uauagcgaag      660

aguucaggau ccauuuuacu uucaaggagu uccaaaauaa ccccaaucca cggucccucg      720

ugaagcccau cacccagcug uugggccgca cccacacggc cacugguauu aggaaagucg      780

ugcgggaacu guuuaacauc accaaugggg cacgcaagaa cgccuucaaa auucucguag      840

ugaucacuga cggcgagaag uuuggcgauc cacuggggua cgaagacguc auucccgagg      900

cggauaggga aggugugauc cgguauguga uuggcgucgg ggacgccuuc cgcagugaga      960

aaagcaggca ggagcugaau accaucgcau ccaagccgcc ccgggaucau guguuucagg     1020

uaaacaauuu cgaagccuug aaaaccaucc aaaaccagcu ccgcgagaag auuuuugcaa     1080

ucgaaggcac ucagacgggu agcaguucca gcuucgagca cgaaaugagu caggagggcu     1140

uuuccgccgc cauuaccagc aacgggccac ugcugagcac ugugggcucc uacgacuggg     1200

ccgggggugu cuuccucuau accaguaagg agaaaagcac cuuuaucaau augacuaggg     1260

uggauuccga caugaacgac gcauaccugg gcuacgccgc cgcaauuauc uugcggaaua     1320

ggguccaaag ccuggugcuc ggggcgcccc gcuaucagca caucggccug guggccaugu     1380

uccggcagaa cacggguaug ugggaaagua augccaacgu aaagggcacc cagauugggg     1440

cauacuuugg cgccucccug uguagcgugg augucgacuc caaugggagu acugauuugg     1500

ugcucaucgg cgcaccacau uauuacgagc aaaccagggg ugggcagguc agcgugugcc     1560

cccugccacg cggccgggcc agguggcagu gugacgccgu gcuguauggu gaacagggcc     1620

aaccgugggg gcgcuucggc gcagcccuca ccguacuggg ggaugugaac ggcgacaaau     1680

ugacugaugu cgcgauuggu gcccccgggg aggaagacaa ucggggcgca guguaccugu     1740

uccacggcac guccgggagc gguaucaguc caucccauag ccagaggauu gccggcucca     1800

agcucagucc ccggcugcag uauuuugggc aaagccuguc cggcggucag gauuugacca     1860

uggacgggcu ggucgaucuc acugugggcg cccagggcca cgugcugcuc cugcgcagcc     1920

agccaguauu gagggucaaa gcaaucaugg aguucaaccc ccgggaggug gcgcgcaaug     1980

uguuugaaug caacgaccaa gucgugaagg ggaaggaggc cggugaagug aggguaugcc     2040

ugcacgucca gaaaaguacc cgggaccgcc ucagggaggg ccagauccag uccgugguga     2100

cuuacgaucu ggcacuggac agcgggcggc cgcauuccag ggccgucuuc aaugagacca     2160

agaacagcac gcgccggcaa acccaggugu ugggccugac ucagaccugu gaaacucuca     2220

aacugcagcu cccaaauugc auugaggauc ccguaagucc caucgugcug agguugaacu     2280

uuagccuggu cgguacccca cuguccgccu ucgggaaccu ccgccccgug cuggcagaag     2340

acgcccaacg guuguuuacg gcgcuguucc cauuugagaa gaauuguggc aacgauaaua     2400

uuugccagga cgaucucagu aucaccuuca gcuuuauguc ccuggacugu cucguggucg     2460

gcgggccgag ggaguucaac gugacuguaa ccgugcgcaa ugauggugaa gacagcuacc     2520

ggacucaggu caccuucuuu uucccccugg auuuguccua uaggaaagug aguacgcugc     2580

aaaaccagcg cagccagcgg uccuggaggc uggccugcga gagugcaagc uccaccgaag     2640

ugagcggcgc ccucaagagu acuuccugua gcauuaauca cccaaucuuu cccgagaacu     2700

ccgaagucac cuucaauauu acuuuugacg uggauagcaa ggccagucug gggaacaaau     2760

ugcugcucaa ggcaaaugua accuccgaga acaauaugcc acgcacgaac aaaaccgagu     2820

uccagcugga acugcccgug aaguacgccg ucuauauggu ggugacuagc cauggcguca     2880

guaccaaaua ccucaauuuu acugcguccg agaacaccag ccgggugaug caacaccagu     2940

aucagguauc caaccugggu cagaggagcu ugccgaucag ucugguguuc cucgucccag     3000

ugcgccugaa ucaaacugug aucugggacc ggccccaggu caccuuuagc gaaaacuugu     3060

ccaguacgug ccauaccaag gagaggcugc caagccacuc cgacuuccuc gccgaacugc     3120

gcaaggcacc cgugguaaau uguagcauug ccgugugcca gaggauccag ugcgauauuc     3180

cguuuuucgg gauccaagag gaauuuaacg caacucugaa aggcaaucuc uccuucgacu     3240

gguacauuaa gaccagucac aaccaucugu ugaucgucag cacugccgag auccuguuca     3300

augauuccgu guuuacccuc cugcccggcc agggggcguu cgugcggagc cagacggaga     3360

ccaaagucga accauuugag gugcccaacc cauugccccu gauuguaggu aguuccgugg     3420

gcgggcuccu gcugcucgcc cugaucacug cagccuugua uaagcugggc uucuuuaaaa     3480

ggcaguacaa ggacaugaug agcgaaggug gcccaccggg ggccgagccc caaugaggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  4528
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt7)

<400>  4528
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucagccuga agacccuccc cuuucuguug cugcuccacg      120

ugcagaucuc caaagccuuc ccagucagua gcaaggagaa aaacacuaag accgugcaag      180

acuaccugga aaaauuuuau caguugccgu ccaaucagua ccagaguacg aggaagaacg      240

gcacuaaugu aauuguggag aagcugaaag aaaugcaacg guucuuuggg cucaacguca      300

ccgguaagcc caaugaggaa acccuggaua ugaugaaaaa gccacgcugc ggcgugcccg      360

acagcggggg cuucaugcug acuccaggua accccaaaug ggagaggacc aaucucacgu      420

aucggauccg caacuacacu ccacagcugu ccgaggcaga aguggagagg gccauuaagg      480

augcguuuga auuguggagc gucgccuccc cgcugaucuu cacccggauu agucaggggg      540

aggcagacau caauaucgcc uuuuaucagc gcgaucaugg cgacaacagc cccuucgaug      600

gcccaaaugg gauucucgca cacgccuuuc aacccgguca gggcaucggg ggcgacgcgc      660

auuucgaugc cgaggaaacu uggaccaaca ccuccgcaaa uuacaaccug uuccuggugg      720

ccgcccacga guuuggucau agcuuggggc ucgcacacag uuccgaccca ggcgcccuga      780

uguaucccaa uuacgcguuc agggaaacga gcaacuacuc ccugccgcag gaugacauug      840

auggcaucca ggccauuuau gggcucagua gcaaccccau ccaaccaacu ggucccucca      900

ccccaaaacc cugugaccca agccugacuu uugacgcaau uaccaccuug cggggcgaga      960

uccuguucuu uaaggaucgc uacuucugga ggcggcaccc gcagcuccag cgcguagaaa     1020

ugaauuuuau cagucuguuc uggcccuccc ugccaacugg gauucaagcc gcauaugagg     1080

acuuugauag ggacuugauc uuccucuuua agggcaacca guacugggcc cugagcgguu     1140

augauauucu gcagggcuac cccaaagaca ucaguaauua uggguuccca uccagcgugc     1200

aggccauuga ugcggcaguc uuuuaccgga gcaagacgua cuucuucgug aacgaccaau     1260

uuuggcgcua ugauaaucag aggcaguuca uggagcccgg cuacccgaaa uccaucagug     1320

gggccuuucc agguaucgaa agcaaggugg acgccgucuu ccagcaagag cacuuuuucc     1380

auguguuuuc cggcccccgg uauuacgcau ucgaucucau ugcccagcgc guaaccaggg     1440

uggcgcgggg gaacaaaugg cugaauugca gguauggcug aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  4529
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt7)

<400>  4529
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguggc agccccucgu gcuggucuug cuggugcucg      120

gcugcuguuu cgccgcacca aggcaacggc aguccacccu gguauuguuu ccgggggacc      180

ugcgcacuaa ccucaccgau aggcagcugg ccgaggaaua ccuguaucgg uacgguuaua      240

cgcgcguggc ggagaugagg ggcgaaagua agagccucgg gcccgcccug uugcugcucc      300

agaaacaacu gucccugcca gagacuggcg aauuggacag ugcaacccuc aaggccaugc      360

ggacccccag gugcgguguc ccagaucugg ggagguucca gacuuuugag ggcgaccuga      420

aauggcacca ucacaauauc accuacugga uucagaacua uagcgaggau cucccccggg      480

cagugaucga cgaugccuuc gcgcgcgccu uugcacugug guccgccgug acgccauuga      540

cuuucaccag ggucuacagc cgggacgccg auauugugau ccaguuuggc guagcagaac      600

auggggacgg uuauccguuc gauggcaagg acgggcugcu cgcccacgcg uuucccccag      660

gccccgguau ucaaggggau gcccauuucg acgacgauga gcuguggucc cugggcaaag      720

gcguggucgu gccaacucgc uuugggaaug cagacggugc cgcaugucac uuccccuuca      780

ucuuugaagg caggaguuac agcgccugca ccaccgaugg gcgguccgac ggcuugccgu      840

gguguagcac gacugccaac uacgauaccg acgaucgcuu cgguuuuugc cccagugaga      900

ggcucuauac ucaggacggc aaugcggaug ggaagccaug ucaguucccc uuuaucuucc      960

agggccaauc cuacagcgca ugcaccaccg acgggcgguc cgaugguuau cgcuggugug     1020

ccacuacggc caacuacgac agggacaagc uguuuggcuu cugcccaacc cgggcagaua     1080

guacugugau gggcgggaau agcgccggug agcugugcgu cuuucccuuc accuuucucg     1140

gcaaagaaua uuccaccugu acuagcgagg ggaggggcga cgggcgccug uggugcgcga     1200

cgaccaguaa cuucgauucc gacaagaaau ggggcuuuug uccagaucag gguuacagcu     1260

uguuccuggu ggccgcacac gaguucgggc augcccucgg ccuggaccac aguuccguac     1320

cggaagcacu gauguauccc auguaccggu uuacugaagg uccacccuug cauaaggaug     1380

acgugaaugg cauuaggcac cucuacgggc cacgccccga gccggagcca cggccaccca     1440

ccaccacuac gccccagccc accgccccac cgacugucug ccccaccggc ccacccacug     1500

ugcacccaag cgaaaggccc accgccgggc cgacgggccc acccagcgca gguccaaccg     1560

ggcccccgac ugccggcccc uccaccgcga cuaccgugcc acugaguccc gucgaugacg     1620

ccuguaacgu gaauaucuuc gaugcaauug ccgagaucgg caaccaacug uaucucuuua     1680

aagacgggaa guacuggcgc uucagcgaag gucggggcuc caggccacag gggcccuuuc     1740

ugauugccga uaaauggcca gcauugccgc ggaagcugga cagcguauuc gaggaacgcc     1800

ucaguaagaa acuguuuuuc uuuuccggcc gccaggugug ggucuauacg ggugcgagcg     1860

ugcuggggcc ccggcgcuug gacaagcugg gccucggcgc cgaugucgca caggugaccg     1920

gggcccugag guccggucgg ggcaaaaugc uccuguucag ugggcgcagg uuguggcggu     1980

uugacgugaa ggcccaaaug guagauccaa ggagcgcauc cgagguggac cgcauguucc     2040

ccggcguccc acuggauacu caugacgugu uccaguaccg ggagaaagcc uauuuuugcc     2100

aggauagguu cuacuggcgc gucagcaguc gguccgaacu caaucaggug gaccaagugg     2160

guuauguaac cuacgauauc cugcaguguc ccgaggacug aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  4530
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt7)

<400>  4530
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg ugcuggccgc auuccucuuu cugagcugga      120

cccauugcag ggccuugcca cugccguccg ggggugacga ggaugaccuc agugaagagg      180

aucugcaguu cgcggaacgg uacuugcgca gcuauuacca ccccacuaac cuggccggca      240

uccucaagga gaaugcagcc uccaguauga ccgaaaggcu gcgggagaug cagagcuuuu      300

ucgggcugga ggucacgggc aaacucgacg auaacacucu ggacgugaug aagaaaccac      360

gcuguggugu acccgaugug ggggaauaua augucuuucc aaggaccuug aaguggucca      420

aaaugaaccu gaccuaccgg auugugaauu auacucccga caugacccau agcgaggugg      480

aaaaggcauu caagaaagcc uuuaaggucu gguccgaugu gacgccacuc aacuucacuc      540

gccugcacga cggcaucgcg gauauuauga ucaguuuugg cauuaaagag cauggggacu      600

ucuacccguu ugaugguccc agcggccugu uggcccacgc auucccaccc gggccaaauu      660

auggcgguga cgcccacuuc gacgaugacg agaccuggac uuccagcagu aagggguaca      720

accucuuucu gguagccgca caugaguucg gccacucccu gggccucgau cauagcaaag      780

accccggggc ccugauguuu ccgaucuaca ccuauaccgg uaagucccac uucauguugc      840

ccgaugacga ugugcaaggc auccagaguc uguacgggcc aggcgacgag gaucccaauc      900

caaaacaccc caagacgcca gacaagugcg auccgagccu cucccuggac gcgauuacua      960

gccugagggg ugaaaccaug aucuuuaaag accgguucuu uuggcgcuug cauccccagc     1020

aagucgaugc cgaacucuuc cugacuaaga guuuuuggcc agaacugccc aacaggauug     1080

acgcagccua ugagcaccca ucccaugauc ucaucuucau uuuucggggc cgcaaauucu     1140

gggcacugaa uggguacgac aucuuggagg gcuaucccaa gaaaauuagc gaacuggggc     1200

ucccgaagga ggugaagaaa aucagugccg ccgugcacuu ugaagauacc gguaagaccc     1260

ugcuguucuc cggcaaccag gucuggaggu acgacgauac uaaucauauc auggacaaag     1320

auuauccacg guugauugag gaagacuucc ccgggaucgg cgauaaggug gacgcgguau     1380

acgagaaaaa cgguuacauu uacuuuuuca auggccccau ccaguuugag uauagcauuu     1440

ggagcaaccg caucgugagg gucaugccag caaacuccau ccucuggugu ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4531
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt7)

<400>  4531
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acacuaccga agacuacgau acgacuaccg      120

aguucgacua uggcgaugcc accccaugcc agaaggugaa ugaaagggca uuuggggccc      180

aacugcuccc gccccuguac agcuuggucu ucgugaucgg ucugguaggc aacauucucg      240

ugguccuggu guuggugcag uauaaacggc ugaagaauau gacuuccauc uaccuccuga      300

accuggcgau uagugaccuc cuguuuuugu ucacccugcc auuuuggauc gauuauaaac      360

ucaaggacga uugggucuuc ggggacgcca uguguaaaau ucugagcggc uuuuacuaua      420

cgggucugua cuccgagauc uucuuuauca uuuugcucac uaucgaucgc uaccuggcaa      480

uugugcacgc cguauucgca cugagggccc ggaccgugac uuuugggguc aucaccagua      540

uuaucauuug ggcgcucgcc auccuggcaa gcaugcccgg cuuguauuuc uccaagaccc      600

agugggaauu uacgcaucac acuugcagcc ugcauuuucc acacgagucc cuccgcgagu      660

ggaagcuguu ccaggcccug aaauugaauc ucuuuggccu ggugcugccc cuccugguga      720

ugaucauuug uuacaccggg aucauuaaga ucuugcugag gcggccaaac gagaaaaaga      780

guaaagccgu ccgccucauu uucgugauca ugaucauuuu cuuccuguuu uggacuccgu      840

auaaucugac caucuugauu agcguauucc aagacuuucu cuucacccau gaaugcgaac      900

aguccaggca ccuggaucug gcagugcagg ucacugaggu gaucgccuac acgcacuguu      960

gcgugaaccc cgucauuuau gcguuugugg gugagcgguu ccgcaaguac cucaggcagc     1020

uguuucaucg gcgcguagcc gugcacuugg ucaaauggcu gccauuccuc agcguggaca     1080

ggcuggaacg ggucaguucc accagccccu ccacuggcga gcaugaacug agugcagggu     1140

ucugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  4532
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt7)

<400>  4532
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aggacccugg ccugccuccu guugcugggc uguggguacc      120

ucgcacacgu gcuggccgag gaagcggaga ucccccggga agucauugag cgcuuggcca      180

ggagccagau ccauuccauu cgggaccugc aacgccuccu ggaaaucgau agugugggua      240

gcgaggacuc ccuggauacc agucucaggg cacacggcgu acaugccacu aagcacgugc      300

cagagaaacg gccgcugccc auucgcagga agcggagcau cgaagaggca gucccagccg      360

ugugcaaaac gcgcacugug aucuaugaaa uucccagguc ccaggucgac ccaaccagcg      420

cgaacuucuu gaucuggccc ccaugugugg agguaaagcg gugcaccggg uguugcaaua      480

cuuccagugu gaaaugucag ccgagccgcg uccaucacag guccgugaag guggccaagg      540

ucgaguacgu gcggaaaaag cccaaacuga aggaaguaca ggugcgccuc gaggaacacc      600

uggagugcgc augugccacc acgagccuga acccagauua uagggaagag gacacuggcc      660

ggccccgcga gagugguaaa aagaggaaac ggaagagguu gaagccaacc ugaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  4533
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt7)

<400>  4533
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacaggugcu gggcccuguu ccucagccug uguugcuacu      120

ugcggcuggu guccgcagag ggcgacccca ucccagagga acucuaugaa augcugagug      180

aucacagcau ucgcuccuuu gacgauuugc agaggcugcu ccauggggac ccgggugagg      240

aagauggcgc cgagcuggac cugaauauga cccggaguca cagcgggggc gagcucgaau      300

cccuggcgcg cgguaggcgg agcuuggggu cccugacuau cgccgagccc gcaaugauug      360

ccgaauguaa gacccgcacg gaggucuucg agaucaguag gcggcucauu gaucgcacua      420

acgcaaauuu ucuggugugg ccacccugcg uagaagugca aagguguagc ggcugcugua      480

acaaucggaa cguccagugc cgcccaaccc aggugcagcu gaggcccgug caaguccgga      540

aaaucgagau cgugcgcaag aaaccaauuu ucaagaaagc caccguaacu uuggaagacc      600

aucucgcgug uaagugcgag accguggccg cagccaggcc ggucacgcgg ucccccggcg      660

ggagccagga acagcgcgcc aagacuccac agaccagggu gacuauccgg accgugaggg      720

uccgccggcc cccaaaaggu aagcacagga aauuuaagca uacccacgau aaaacggcac      780

ugaaggagac ucugggcgcc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  4534
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt7)

<400>  4534
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguucg gccuccuguu gcugaccucc gcccucgcag      120

ggcagaggca agguacucag gccgagagua accugagcuc caaguuucag uucaguagca      180

auaaagaaca gaacggcgug caagaccccc agcacgagcg gaucauuacc gucuccacga      240

augggagcau ccauucccca cgcuuuccgc acacuuaccc caggaacacc guguugguau      300

ggcggcuggu ggcggucgaa gagaaugugu ggauucagcu caccuucgau gaacgcuuug      360

gccuggagga cccagaggau gacaucugca aguaugauuu cguggaaguc gaggaaccca      420

gugacgguac uauucugggg agguggugug gcagcggcac cgugccaggg aaacagaucu      480

ccaaggguaa ccaaauccgg auucgcuuug uaagcgauga guacuucccc agugagccag      540

gcuuuugcau ccauuauaau auugugaugc cgcaguucac ggaagccguc ucccccagcg      600

ugcucccacc cuccgcacug ccauuggacc ugcucaacaa ugccaucacu gcauuuagua      660

cccuggagga ucugauuagg uacuuggaac ccgagcggug gcagcucgac cuggaagauc      720

uguaucgccc gacuuggcag cuccugggga aagccuucgu guucggcagg aaaagccggg      780

ucguggacuu gaaccugcuc accgaggagg uacgccugua cuccuguacc cccaggaauu      840

uuagcgugag uauccgggag gaacugaagc gcacggauac uauuuucugg ccagguugcu      900

ugcucgucaa gagguguggg ggcaacugcg cguguugccu gcacaauugu aacgaaugcc      960

aaugcgugcc cuccaaggug accaaaaagu aucaugaggu ccugcagcuc cggccaaaaa     1020

cuggcgugcg cgggcugcac aagagcuuga ccgacguagc ccuggaacac caugaggagu     1080

gugacugcgu guguaggggu aguaccggcg ggugaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  4535
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt7)

<400>  4535
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaggcuga ucuucgugua cacccucauu ugcgccaacu      120

uuuguagcug ccgggacacu uccgcaacgc cccagagugc cagcaucaag gcgcugcgca      180

augccaacuu gaggcgggau gaccuguauc gcagggauga gaccauucaa gucaaaggca      240

auggguacgu gcagucccca cgguucccga acaguuaucc ccgcaaucuc cuguugacuu      300

ggaggcugca uagccaggaa aacacccgga uccagcucgu auuugacaau caauucgguc      360

uggaggaagc agagaacgau auuugucgcu acgacuuugu ggaagucgag gauaucuccg      420

agaccagcac uaucauuagg ggccgguggu gcgggcacaa ggaagugcca ccccgcauca      480

aauccaggac caaucagauu aagaucacgu ucaaaaguga cgauuauuuu guggccaagc      540

caggcuucaa gauuuacuau agccugcucg aggacuuuca gcccgcagcc gcguccgaaa      600

cuaacuggga gagcgucacc aguuccauca gcgguguguc cuacaauagu ccaagcguaa      660

cugauccgac ccugauugcc gacgcauugg auaaaaagau cgccgaguuc gacaccgugg      720

aagaccugcu caaauacuuu aaccccgagu ccuggcagga agaucuggag aauauguauc      780

uggacacgcc acgguaccgc gggaggagcu aucaugaucg gaagaguaaa gucgacuugg      840

aucgccucaa cgacgaugcc aagagguacu ccuguacucc ccggaauuau agcgugaaca      900

ucagggagga acugaaacug gcaaacgugg ucuucuuccc acgcugccuc cuggugcaac      960

gguguggcgg caauugcggg ugugguaccg uaaacuggag gaguugcacu ugcaauuccg     1020

gcaagaccgu gaagaaauac cacgaggucu ugcaguuuga acccgggcau auuaagcgcc     1080

ggggcagggc caaaaccaug gcgcuggugg acauccagcu cgaucaccac gagcgcugug     1140

acugcauuug uagcagccgg ccgcccaggu gaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  4536
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt7)

<400>  4536
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugacccaca gcaaguuccc cgccgcaggc auguccaggc      120

cacuggacac cagucuccgg cugaaaacuu uuagcuccaa gagugaguac caguuggucg      180

ugaacgccgu acgcaaacug caagaaagcg gguucuauug guccgcggug acggguggcg      240

aggccaaucu ccuguugagc gcagaaccgg ccgggacuuu ucugaucagg gauuccagug      300

accagcggca uuucuuuacc cucagcguca agacccaguc cggcacuaaa aaccugcgca      360

uucagugcga gggugggagc uucagucugc aauccgaucc caggagcacc cagccagugc      420

cccgguuuga cugugugcuc aagcuggucc accauuacau gccaccccca ggcgcaccgu      480

ccuuccccag uccacccacg gaaccaagcu ccgaggugcc cgagcagccg agcgcccagc      540

ccuugccagg caguccccca cgcagggcgu auuacaucua uuccgggggu gaaaagauuc      600

cccugguacu cagccggcca cugaguucca auguggccac ucugcaacac uugugccgca      660

aaaccgucaa cggccaucuc gauagcuacg agaaggugac ucagcugccg gggcccauca      720

gggaauuucu ggaccaguau gaugcaccac ucugaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  4537
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt7)

<400>  4537
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugcccagcg ccggccagcu ggcacucuuc gcccugggga      120

ucgucuuggc ggccugccaa gcacuggaga acuccaccag uccacucagc gccgacccgc      180

ccguggcagc cgcgguagug ucccacuuua augauugucc agacagucau acucaguucu      240

gcuuucacgg uaccuguagg uuccuggucc aggaagauaa gcccgccugc gugugucaua      300

gcggcuacgu gggggcacgg ugcgagcacg ccgacuugcu ggccgucgug gcagccuccc      360

agaaaaagca agcgauuacg gcccucguag uggucagcau cguggcacug gccgugcuga      420

uuaucacuug uguccucauu cauugcuguc aggugcgcaa acacugcgaa uggugcaggg      480

cacugaucug ucggcacgag aagccauccg ccuugcugaa aggccgcacc gccugcuguc      540

auagugaaac cguaguguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  4538
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt7)

<400>  4538
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccccaagcg gccugaggcu ccugccguug cugcuccccc      120

uguuguggcu gcucgugcug accccagggc ggcccgccgc aggucugucc acuugcaaga      180

ccaucgacau ggagcucguc aaacgcaaga ggauugaagc cauccggggc cagauucuga      240

guaaauugcg ccuggcgagc ccacccuccc aaggggaggu gccaccgggc ccccucccag      300

aagccguacu ggcacuguac aacaguacga gggaucgggu ggccggugag agcgcagaac      360

ccgagccaga gcccgaagcc gacuauuacg cgaaggaggu cacucgcgug uugauggugg      420

aaacccacaa ugagaucuau gauaaauuca agcaguccac ccauagcauu uacauguuuu      480

ucaacacuuc cgagcucagg gaagccgucc cggagcccgu gcugcugagu cgggcagaac      540

uccgccuguu gaggcugaag cucaaaguag agcagcacgu ggaacuguau cagaaguaca      600

gcaauaacuc cuggcgguau cugagcaauc gcuugcucgc cccaagugac ucccccgagu      660

ggcugagcuu ugaugucacc ggggugguga ggcaauggcu gucccggggc ggcgagaucg      720

aaggguuccg ccucagugcc cauuguagcu gcgacuccag ggauaacacg cugcaggucg      780

acaucaaugg uuuuacuacc ggccggcgcg gggauuuggc aacuauucac ggcaugaaca      840

ggccauuccu gcuccugaug gccacgcccc uggagcgggc gcagcauuug cagagcagua      900

ggcaccgccg ggcccucgac accaauuacu guuuuuccag caccgagaaa aacugcugug      960

ugaggcaacu guacaucgau uuccgcaagg accuggguug gaaauggauu cacgaaccaa     1020

agggguauca ugcaaauuuu ugccucggcc cgugucccua caucuggagu cuggauacuc     1080

aguauuccaa aguauuggcc cuguacaacc agcacaaucc aggcgcaagc gccgcccccu     1140

gcugugugcc acaggcgcuc gaaccccugc cgauugucua uuacgugggg cggaagccaa     1200

agguggagca acugagcaac augaucguca gguccugcaa augcaguuga ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  4539
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt7)

<400>  4539
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg ugcugagcgc cuuccucauc cugcauuugg      120

ucaccguggc acugucccuc aguacuugua gcacccugga cauggaucag uuuaugagga      180

agcggauuga ggccauccgc ggccaaauuu uguccaaacu gaagcucacg agucccccag      240

aagacuaucc ggagcccgaa gagguaccac ccgaagugau cagcauuuac aacuccacua      300

gggaucugcu gcaggagaaa gcgagccggc gcgccgcagc cugcgagagg gaacgguccg      360

acgaggaaua uuacgcaaag gaggucuaua aaaucgauau gccacccuuc uuuccaagug      420

agaaugccau cccgcccacc uucuaccgcc cauauuuuag gauugugcgg uucgacguga      480

gcgcgaugga aaagaacgcc uccaaucucg ucaaggcaga guuucgcgug uucaggcugc      540

agaaccccaa agcccgggua ccagaacagc gcaucgaguu guaccaaauu cucaagagca      600

aagaucugac cagucccacu cagagguaca ucgacuccaa gguggucaaa acccgggccg      660

aaggggagug gcugagcuuu gaugugacgg acgcagugca cgaguggcug caucacaagg      720

aucgcaauuu ggguuucaaa auuucccucc auuguccgug cuguacuuuu guccccagua      780

acaauuauau cauuccaaac aagagcgagg aacuggaagc cagguucgcg ggcaucgacg      840

ggaccuccac uuacaccagc ggcgaucaga agaccaucaa aaguacgcgg aagaaaaauu      900

ccgguaagac uccccaucug cuccugaugu ugcugccaag cuaucgccuc gagagucagc      960

aaaccaacag gcggaaaaag agggcccugg acgcagccua cugcuuccgc aaugugcagg     1020

acaacuguug ccugcggccc uuguauauug auuuuaagag ggaccucggg uggaaaugga     1080

uccacgaacc aaagggcuac aaugcaaacu ucugugccgg cgccugcccg uaucuguggu     1140

ccagcgauac ucagcacagc cgcguacugu cccucuacaa uaccauuaac cccgaggcga     1200

gugcaagccc augcugugug ucccaggacc uggagcccuu gaccauccug uacuauauug     1260

ggaaaacucc aaagaucgaa caacucagca acaugaucgu caaaaguugc aaguguuccu     1320

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  4540
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt7)

<400>  4540
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcauc ugcagagggc ccucgugguc cuggcauugc      120

ugaacuucgc caccgugagc cucucccuga guacuugcac cacguuggac uuuggccaca      180

ucaaaaagaa acggguagag gcgauucgcg ggcaaauccu gagcaagcuc aggcugacuu      240

ccccacccga accgaccgug augacccacg uccccuacca ggugcuggcc cucuauaaua      300

guacucggga gcuguuggaa gagaugcaug gugaacgcga ggagggcugu acccaggaaa      360

acacggagag cgaauacuau gcaaaagaga uucacaaguu cgauaugauc caggggcugg      420

ccgagcauaa ugaacucgca gugugcccaa agggcauuac uuccaaaguc uuuagguuca      480

acgugagcuc cguagagaag aaucggacca accuguuucg cgccgaguuc agggugcugc      540

ggguccccaa uccaaguagc aaacgcaacg aacaaaggau cgaauuguuu cagauccucc      600

ggcccgacga gcacauugcg aagcagcgcu acaucggugg gaaaaaucug ccaacuaggg      660

gcaccgccga guggcugucc uucgauguga ccgacacggu gcgggaaugg cuccugcgca      720

gggagagcaa cuugggccug gaaauuagua uccacugucc gugccauacu uuucagccca      780

auggggauau ucucgagaac auccacgaag ucauggagau uaaguucaaa gguguggaca      840

augaggauga ccauggccgc ggggaucugg gccggcugaa gaagcaaaaa gaccaccaca      900

acccacauuu gauccucaug augauucccc cacacaggcu ggauaauccc ggucaagggg      960

gccagcggaa gaaaagggca cuggacacca acuauuguuu ucgcaaccuc gaagagaauu     1020

gcuguguacg gccgcuguac aucgauuuca ggcaggacuu gggcuggaag ugggugcaug     1080

aacccaaagg guauuacgcc aacuucugcu ccgguccaug ucccuaccug cgcagcgccg     1140

acacuaccca cuccaccguc cucggccugu auaauacucu gaacccagag gcaagugcca     1200

gccccugcug cgugccacag gauuuggaac cgcucacgau ccuguacuau guggggcgga     1260

cccccaaggu cgagcagcug uccaauaugg ugguaaagag cuguaaaugc aguugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4541
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt7)

<400>  4541
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccccgugg cagucugggc cgcgcuggcc gugggccucg      120

agcugugggc agccgcacac gccuugccag cgcagguagc cuucaccccg uacgcacccg      180

aaccagggag cacuugcagg cugcgggagu auuacgacca aaccgcccag auguguugcu      240

ccaaguguag ucccggucag caugccaaag uguuuugcac gaagacuagc gauaccgucu      300

gugacuccug cgaagauagu accuauacuc agcucuggaa cugggugcca gagugucuga      360

gcugcggcuc ccgcuguagc uccgaccaag uggaaaccca ggcaugcacg agggagcaga      420

aucggaucug cacuugucgc cccggguggu acugcgccuu gaguaaacag gagggcugua      480

ggcugugcgc gccacuccgg aagugucgcc cggguuucgg ggucgccagg cccggcaccg      540

aaacuagcga ugugguaugc aaaccaugug cacccggcac cuuuuccaac accacgagca      600

guacugacau uugccggcca caccaaaucu guaauguggu cgccauuccc gggaacgcau      660

ccauggaugc cgugugcacc agcacuuccc cgacccgcag uauggccccc ggugcggugc      720

aucugccaca gcccgucagc accagguccc agcacacuca gccaacgccc gagccaagca      780

ccgcaccgag uacuuccuuc cugcucccca ugggcccaag ucccccagcc gaagggagca      840

ccggcgacuu ugcccugccc guggguuuga ucguaggggu gaccgcacug ggccuccuga      900

uuaucggcgu cgugaauugc gugaucauga cucaagucaa gaagaaaccg cuguguuugc      960

agcgggaggc caaggugcca caucuccccg cggauaaagc ccgcgggacg cagggucccg     1020

agcaacagca ucugcugauu accgcaccau ccagcagcuc caguagccuc gaauccagcg     1080

ccagugcacu ggacaggcgg gcccccacuc gcaaccagcc acaggccccg ggcguagagg     1140

cauccggggc cggcgaagcg agggccagca ccgguuccag ugauagcucc cccggcgggc     1200

acggcaccca agugaauguc acuugcaucg ugaacgucug uagcaguucc gaccacagcu     1260

cccagugcag uagccaggca uccagcacga ugggggauac cgacaguucc ccaagcgagu     1320

cccccaagga cgaacaggug ccauucagca aagaggagug ugccuuucgg agucaauugg     1380

aaacucccga gacccugcuc gguagcacug aagagaagcc gcugccacug ggcgugcccg     1440

augccgggau gaaaccaucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  4542
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt7)

<400>  4542
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgugauga ggcuguuccc augcuuucuc cagcuguugg      120

ccggccuggc acucccggcc gugcccccac aacagugggc gcugagcgcc gggaacgguu      180

ccagugaggu cgaaguagug cccuuccagg aggucugggg ccggagcuac ugucgcgcau      240

uggaaaggcu gguggacgug gucuccgagu auccaaguga aguggagcac auguuuagcc      300

ccuccugcgu aagccuccug cgguguaccg ggugcugugg cgaugagaau cugcauugcg      360

ugccagucga aacugccaac gugaccaugc agcuccugaa gauccgcucc ggugacaggc      420

cgaguuacgu ggaguugacg uucagccaac acguccggug ugaaugccgc ccccugaggg      480

agaaaaugaa gccagagcgg cgcaggccca aagggcgggg caagcgcagg cgggaaaaac      540

agcgcccaac ugauugucau cucugcggcg acgcagugcc caggcgguga ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  4543
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt7)

<400>  4543
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgacaggc agacugauac cgcccccagc ccauccuacc      120

aucugcuccc gggccggcgc aggacggugg acgcagccgc gagucggggg caaggucccg      180

agccagcccc cggcgggggc gucgaaggug ugggggcacg cggcguagcc cugaaguugu      240

ucgugcagcu gcucggcugc agcagguuug ggggugcagu cgugcgggcc ggcgaggcgg      300

aaccauccgg ggccgcacgc agugccagcu ccggcaggga ggaaccccag ccagaggagg      360

gugaagagga agaggagaaa gaagaggaac gggggccgca guggcgccug ggcgccagga      420

agcccggcag cuggacuggg gaggcagccg ugugugcgga uuccgcccca gcagcccggg      480

caccccaagc cuuggcccgc gcgaguggua ggggcgggcg ggucgcacgc aggggcgccg      540

aagagagcgg uccaccccac uccccgagcc ggcgcggcag ugccuccagg gcagggcccg      600

gccgggccag cgagaccaug aacuuccugc ucuccugggu gcacuggagu cuggcgcugc      660

uccuguauuu gcaucacgcc aaauggagcc aggcagcccc aauggcagaa ggggguggcc      720

agaaucauca cgagguagug aaguuuaugg acgucuacca gagguccuau ugccacccca      780

ucgaaacccu gguggauauu uuccaagagu acccagacga aaucgaguau auuuuuaaac      840

ccagcugugu gccacucaug cgcugcgggg gcuguugcaa cgaugagggu cuggaaugug      900

ucccgacuga ggaaaguaau aucaccaugc agauuaugcg gaucaagccc caucagggcc      960

agcacaucgg ggagaugucc uuccugcaac auaacaagug cgaauguagg cccaaaaagg     1020

accgcgcccg gcaggagaaa aagagcguga ggggcaaagg gaagggccag aaacgcaagc     1080

ggaagaaaag uagguacaag uccuggagcg uauauguggg ugcccggugc ugcuugaugc     1140

cauggagccu cccagggccc cacccgugug gcccaugcuc cgagcgcagg aaacaccugu     1200

uuguccaaga uccccagacg uguaagugca guuguaaaaa uacugacagc cggugcaagg     1260

cacgccagcu ggaacucaac gagaggaccu gucggugcga uaagcccagg cgcugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4544
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt7)

<400>  4544
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggucc cuggccuugc      120

ugcucuaccu gcaucacgca aaguggaguc aggccgcgcc cauggccgag ggcggggguc      180

aaaaucauca cgaagucgug aaauuuaugg acguauauca gaggagcuac ugccauccaa      240

ucgagaccuu gguggauauu uuccaggaau auccggacga gaucgaauac auuuuuaagc      300

ccuccugugu cccacugaug cggugcggcg gguguugcaa cgaugagggc cucgagugug      360

ugcccacuga agagaguaau aucaccaugc agauuaugcg caucaaacca caccaagguc      420

agcacaucgg ggaaaugagc uuccugcagc auaacaagug cgaguguagg cccaaaaagg      480

accgggcacg ccaggagaag aaauccguga ggggcaaggg caaagggcaa aagcggaaac      540

gcaagaaaag cagguauaag uccuggagug ucuacguggg ugcccggugc ugucugaugc      600

cauggagccu cccgggcccc cacccaugcg ggcccugcuc cgaacgcagg aagcaucugu      660

uuguacagga uccacagacg uguaaaugca gcuguaagaa uacugacagu cggugcaaag      720

cacgccaguu ggagcugaac gaaaggaccu gucggugcga uaagcccagg cgcugaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  4545
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt7)

<400>  4545
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcccccugc ucaggcggcu guugcuggcc gcacuccugc      120

aguuggcccc agcgcaagcc ccgguguccc agcccgacgc accaggccac cagcgcaagg      180

ucgugaguug gaucgaugua uacaccaggg ccacuugcca gccccgggag guggucgugc      240

cacugaccgu ggaacucaug gggacggucg caaaacaacu ggugcccagc uguguaacug      300

ugcagcgcug cgguggcugu ugcccagacg augggcugga gugugucccg accggccagc      360

aucaggugag gaugcaaauu cucaugaucc gguaucccuc cagucagcug ggugaaauga      420

gcuuggagga acacucccag ugcgaguguc gcccaaagaa aaaggacagc gccgugaaac      480

ccgauagggc ggccacccca caucaccggc cccagccgcg cuccgucccc gggugggaca      540

gugcaccagg cgcccccagc ccagccgaua uuacucaucc caccccagca ccgggccccu      600

ccgcccacgc ggccccaagc acgaccagug cacugacucc cgggccagcc gcagccgccg      660

cggacgcagc cgccuccagc guggcaaagg guggcgccug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  4546
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt7)

<400>  4546
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caucugcucg gcuucuuuag cguggccugc ucccuguugg      120

cagccgcgcu gcuccccggg ccaagggagg ccccggcagc cgcagccgcg uucgaaagug      180

gucuggacuu gagcgaugcc gagcccgacg caggcgaagc caccgccuac gcauccaagg      240

aucuggagga acagcuccgg agugucagcu ccguggacga gcugaugacu guacuguauc      300

cagaguacug gaaaauguau aagugucaac uccgcaaagg gggcuggcag cacaacaggg      360

aacaggccaa ucugaacagc cggaccgagg aaacgaucaa guuugcggcc gcacacuaca      420

auacugagau uuugaaaucc aucgauaacg aguggcgcaa gacccagugc augcccaggg      480

aaguguguau ugacgucggu aaggaguucg ggguggccac caauacuuuc uucaaaccac      540

ccugcgugag ugucuaucgg uguggcggcu gcuguaacag cgaagggcug caaugcauga      600

auaccuccac gagcuaccuc aguaagacuc uguuugagau caccgugcca cugucccagg      660

guccgaaacc cguaacuauu agcuucgcaa accauaccuc cugucgcugc augaguaagu      720

uggaugugua uaggcagguc cacagcauca uccggcgcuc ccucccagcc acccugcccc      780

agugccaagc cgcgaauaaa acguguccaa cuaacuacau guggaauaac cauauuugua      840

ggugccuggc acaggaagac uuuauguuca gcagugaugc cggcgacgau uccaccgacg      900

gguuucacga uaucugcggc cccaauaagg agcucgacga ggaaacuugu cagugcgugu      960

gucgggccgg ucugcgcccg gcaagcugcg ggccccacaa agaguuggac aggaacaguu     1020

gucagugcgu gugcaagaau aagcuguucc caucccaaug uggcgccaac cgggaauuug     1080

augagaauac cugccagugu gucugcaaac gcaccugucc caggaaccag ccacucaacc     1140

ccggcaagug cgcgugugaa ugcacugaga gcccacaaaa augucugcug aaggggaaaa     1200

aguuucauca ccagacgugc agcuguuacc ggcgcccgug caccaauagg cagaaggccu     1260

gcgagcccgg uuucuccuau agugaagagg ugugucggug cguaccaagc uacuggaaaa     1320

ggccccagau guccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  4547
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt7)

<400>  4547
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagggagu ggguggucgu gaacguauuc augaugcugu      120

augugcagcu cguccaaggc agcuccaaug aacacgggcc cgugaagcgg aguagccagu      180

ccacccugga gcgcagugaa cagcagauca gggccgcaag cuccuuggag gaacugcucc      240

ggauuacuca uagcgaggac uggaaacugu ggcgcugcag guugcggcug aaguccuuua      300

ccaguaugga uagccgcucc gccagccaca ggaguacgcg guucgcggcc acuuuuuacg      360

acaucgagac ccucaaagug auugaugaag aguggcaacg cacccagugu uccccaaggg      420

aaacuugcgu cgagguggca agcgagcugg guaaguccac caacacguuc uuuaaaccgc      480

ccuguguaaa uguguuccgg ugcggcgggu guugcaacga agagagucug aucuguauga      540

auacuagcac cuccuauauu agcaagcagc ucuuugaaau caguguccca cugacuuccg      600

ugcccgaguu ggugccaguc aagguggcca accauaccgg cugcaaaugu cugcccaccg      660

caccacgcca cccguacagc aucauuaggc ggaguaucca gauucccgaa gaggaccgcu      720

gcucccauag caagaaacuc ugcccaaucg auaugcugug ggacagcaau aaguguaaau      780

gcguacugca agaggaaaac cccuuggccg guacggagga ucacucccac cuccaggaac      840

cagcgcugug ugggccccau augauguucg acgaggauag gugcgaaugu gugugcaaga      900

cuccgugucc caaagaccug auucagcacc caaagaauug caguuguuuu gagugcaagg      960

agagccucga aaccugcugu cagaaacaua agcuguucca ccccgauacu ugcuccugug     1020

aggaccggug cccauuucac acccgccccu gugccagcgg caaaaccgca ugcgccaagc     1080

auuguagguu cccaaaagaa aagcgggccg cacaaggccc gcacaguagg aagaaccccu     1140

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  4548
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt8)

<400>  4548
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg aaaccggcuu cgaacacucc ggccucuggg      120

ucuccguccu cgccggccua cuacuaggcg ccugccaagc ccaccccauc cccgacucau      180

ccccacuucu acaauucggc ggacaaguca gacaacgaua ccucuacacc gacgacgccc      240

aacaaacaga agcccaucuc gaaauaagag aagacggcac cgucggcggc gccgccgacc      300

aaucccccga aucccuacuc caacucaaag cacucaaacc cggcgucauc caaauccucg      360

gcgucaaaac cucccgcuuc cuaugccaac gccccgacgg cgccuuauac ggcucccuac      420

acuucgaccc cgaagccugc ucuuuucgcg aacuccuacu cgaagacggc uacaacguau      480

accaauccga agcccacggc cuaccccuac accuccccgg caacaaauca ccccaccgcg      540

acccagcccc acguggcccc gcacgcuucc ucccacuacc aggccuccca cccgcccucc      600

ccgaaccacc cggcauccuc gcaccccaac cacccgacgu aggcuccuca gacccccucu      660

ccauggucgg ccccucccaa ggccgcucac ccucauacgc cucauaagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  4549
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt8)

<400>  4549
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuccuucc caccccuccu ccuacuucuc uucuggggcg      120

uaguauccca cuccuucccc gccacacuag aaacccaaga acaagacgua gaccuggucc      180

aaaaauaccu agaaaaauac uacaaccuca agaacgaugg acgacaaguc gaaaaacgcc      240

gcaacuccgg cccggucgua gaaaagcuaa aacaaaugca agaguucuuc ggccuaaaag      300

ucacuggcaa accagacgcc gaaacccuca aagucaugaa acaaccacga ugcggcgucc      360

cagacgucgc acaauucguc cucacagaag gcaacccccg augggaacaa acccaccuca      420

ccuaccgaau ugaaaacuac acaccugacc ugcccagagc cgacguagac cacgccauag      480

aaaaagccuu ucaacucugg ucaaacguca caccccucac cuuuaccaaa gucucggaag      540

gccaagccga cauaaugauu agcuucguuc gaggcgacca cagagacaac ucccccuucg      600

acggacccgg cggcaaccuc gcccacgccu uccaacccgg cccggguaua ggcggagaug      660

cacauuucga cgaagacgaa cgcuggacaa acaacuucag agaauacaac cuccaccgug      720

uagcagccca cgaacuaggc cacucacucg gacucucaca cagcaccgac aucggagccc      780

uaauguaccc auccuacacu uucuccggag acguucaacu cgcccaagac gacaucgacg      840

gcauccaagc aaucuacggc cgcucccaaa acccaguaca acccaucgga ccacagacuc      900

ccaaagccug cgacuccaaa cucaccuuug acgcaaucac caccauccga ggcgaaguca      960

uguucuucaa agaccgcuuc uacaugcgca cgaaccccuu cuacccagaa gucgaacuca     1020

acuucauauc agucuucugg ccccaacuac caaacggccu ugaagcagca uacgaauuug     1080

ccgacagaga cgaaguccgc uucuucaaag gaaacaaaua cugggccguc caaggccaaa     1140

acguccuuca cggcuacccc aaggacauau acuccuccuu cggcuucccc cgaacaguca     1200

aacacaucga cgcggcacug uccgaagaaa auaccggcaa gacauacuuc uucgucgcca     1260

acaaauacug gcgguacgac gaauacaaac gauccaugga ccccggcuac cccaaaauga     1320

uagcacacga cuucccggga aucggccaca aagucgaugc aguauucaug aaagacggau     1380

ucuucuacuu cuuccacggc acacgccaau acaaauucga ccccaaaaca aaacgcaucc     1440

ucacccucca gaaagccaac agcugguuca auugccgcaa aaacuaagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  4550
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt8)

<400>  4550
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuccuucc cuccccuacu acuccuacua uucuggggag      120

ucguaucaca cuccuucguc cucaccgaag gcaacccucg augggaacaa acccaccuca      180

cuuaccgaau cgagaacuac acccccgacc ucccacgagc cgacgucgac cacgccaucg      240

aaaaagccuu ucaacuaugg uccaacguca caccccucac cuucacuaaa guaagcgaag      300

gccaagccga caucaugauc agcuucgucc gcggagacca ccgagacaau ucccccuucg      360

acggcccagg aggcaaccua gcccacgccu uucaaccagg acccggcaua ggaggcgacg      420

cccacuucga cgaagacgaa cgauggacaa acaacuuccg cgaauacaac cuccacagag      480

uagccgccca cgaauuaggc cacucccuag gacucucaca cucaaccgac auaggugccc      540

ucauguaccc cuccuacacc uucagcggcg acguccaacu agcccaagac gacaucgacg      600

gcauacaggc caucuacggc cgaucucaaa auccagucca acccauagga ccacagacac      660

caaaagccug ugacuccaaa cucaccuucg acgccaucac caccauacgc ggagaaguca      720

uguucuuuaa agacagauuc uacaugcgua ccaaccccuu cuacccagaa guagaacuaa      780

acuucauauc ugucuucugg ccacaacucc ccaacggccu agaagcagca uacgaauuug      840

cugacagaga cgaaguacga uucuucaaag gcaacaaaua cugggccguc caaggccaaa      900

acguacuaca cggcuaccca aaagacaucu acuccuccuu cggcuucccc cgcacaguca      960

aacacaucga ugccgcacuc agcgaagaaa acaccggaaa aaccuacuuc uucgucgcca     1020

acaaauacug gcgauacgau gaauacaaac gauccaugga ccccggauac cccaaaauga     1080

ucgcccacga cuuccccgga auaggccaca aagucgacgc aguuuucaug aaagacggcu     1140

ucuucuacuu cuuccacgga accagacaau acaaauucga ccccaaaacc aaacgcaucc     1200

ucacccucca aaaagccaac uccugguuca acugccgcaa aaacuaagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  4551
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt8)

<400>  4551
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaaaaaca uccucaaaau acucauggac ucguauucua      120

aggaauccaa aauccaaacc gucagacgcg ucacuagcgu cucccuccuc gcgguguacc      180

uaacuaugaa uacguccagc cuaguccucg caaagccuau cgagaacacc aacgacacca      240

gcauuaaaaa cguugagaag cuacgcaacg cgccaaacga ggaaaacuca aagaaagucg      300

aagacagcaa aaaugacaaa guagagcacg uuaaaaacau agaagaagcc aagguggaac      360

aaguagcacc ggaagucaaa agcaaaagua cccuacgcag cgccagcauu gccaacacca      420

acagcgaaaa guacgacuuc gaguaucuua acgggcucag cuacacagaa cuaacaaacc      480

ugaucaaaaa cauaaaaugg aaccaaauaa acgguuuguu caacuacagc acagggucac      540

aaaaauucuu cggcgauaaa aaccgcgucc aggccaucau aaacgcccua caagaaagcg      600

gccgcacaua caccgcgaac gacaugaagg gaauagaaac cuucacggag guauuaaggg      660

cgggguucua ccuaggcuac uacaaugacg gacucucaua ccuaaacgac cgcaacuucc      720

aagacaagug cauccccgcc augauagcca uacagaaaaa cccaaauuuu aaacucggca      780

cggccgucca agacgaaguu auaacauccu uagggaaacu caucggaaac gccucggcca      840

acgccgaagu ggugaacaac ugcguccccg uacuuaagca auuccgcgaa aaccuaaacc      900

aauacgcacc cgacuacguu aaggggaccg cggucaacga auugauaaaa ggaaucgagu      960

ucgacuuuag cggagcagca uaugaaaagg acgugaagac aaugcccugg uacggcaaga     1020

uugauccguu cauuaacgaa cucaaggccc ucggacuaua cggaaacaua accucagcaa     1080

ccgagugggc uucagaugua ggcaucuacu accugagcaa guucggccua uacagcacca     1140

accgcaacga cauugugcaa aguuuagaaa aagcagucga cauguacaag uacggcaaga     1200

uugcauuugu agcgauggaa cgaauaacgu gggacuacga cggcaucggc uccaacggaa     1260

agaaagucga ccacgacaag uuccuggaug acgccgagaa gcacuaccuc cccaagacau     1320

acaccuucga caacggcacc uucaucaucc gagccggcga caaaguaucg gaagaaaaga     1380

ucaagagacu auacugggcc uccagagaag ucaaauccca auuccaccga gucgucggaa     1440

acgacaaggc ccuagaagua ggaaacgccg acgacguauu aacuaugaaa auuuuuaaca     1500

gcccagaaga auacaaauuc aacaccaaua uuaacggcgu aucaacagac aacggaggac     1560

uguacauaga accccgaggg acauucuaca cauacgaacg gaccccacaa caauccaucu     1620

uuagccugga agaacucuuc agacacgaau acacccacua ccuacaggcc agauaccuag     1680

ucgacgguuu auggggacaa ggccccuucu acgagaaaaa ccgacucaca ugguuugacg     1740

agggcacagc cgaguucuuc gcaggaucaa caagaaccag cggcgugcuc ccgcgaaagu     1800

cgauccuugg cuauuuagcg aaagacaaag uagaccacag auacagccua aagaaaacac     1860

ugaacucagg cuacgacgau agcgacugga uguucuacaa cuauggcuuc gcaguagcgc     1920

acuaccuuua cgaaaaagac augccgacgu ucaucaagau gaacaaagca auacuaaaca     1980

ccgacguuaa aucguacgac gaaauaauca aaaagcuguc cgacgaugcc aacaaaaaca     2040

cagaauacca aaaccauauc caggaacucg cggacaagua ccagggggca ggaauccccc     2100

uagucucgga cgacuaccua aaagaccacg gcuacaagaa agcaagcgaa guauacagug     2160

agaucagcaa agccgccucc cuaacgaaca caucagugac ugcugagaaa agccaguacu     2220

ucaacaccuu cacacuccga ggaacuuaca cgggagaaac aucaaaaggc gaguucaaag     2280

acugggacga aaugagcaag aaauuagacg gcacccuaga aucacuagcg aaaaacucuu     2340

ggagcggaua caagacccuu accgcauacu ucacgaacua cagggucacc agugacaaca     2400

aagugcagua cgacgucgug uuccacggag uucuaacaga caacgccgac aucuccaaua     2460

acaaagcacc aaucgccaag gugacggggc caagcacagg agccgucgga cgaaacauag     2520

aguucucagg caaagacagc aaggacgaag acgggaagau aguaaguuac gacugggacu     2580

ucggugacgg agcaacaucc cgcgguaaga acagugugca cgcauauaag aaggccggaa     2640

cauacaacgu aacccuaaag guaacggacg acaaaggagc gacagcgacc gaaucguuua     2700

cuaucgaaau aaagaacgaa gacacgacca cuccaauaac aaaagaaaug gaaccaaacg     2760

augacaucaa agaagccaac ggcccuauag ucgaaggugu aaccguaaaa ggcgaccuca     2820

acggcuccga cgacgcagac acguucuacu ucgacgugaa agaagacggg gacguaacaa     2880

ucgaacuccc cuacuccggc uccucaaacu ucaccuggcu aguauacaag gaaggggacg     2940

aucaaaacca caucgcaagc ggaaucgaua aaaacaauag uaaaguaggg accuucaaau     3000

cgacaaaggg aaggcacuac gucuucauuu acaagcacga cagcgccagc aacauaaguu     3060

acuccuuaaa caucaaagga cuaggcaacg aaaaacuuaa ggaaaaagag aacaacgacu     3120

caagcgacaa agcgacugua aucccaaacu ucaauacgac aaugcaaggu ucccuccucg     3180

gagacgacuc acgggacuac uacagcuucg aagucaagga agaaggcgaa gugaacaucg     3240

aacuggacaa aaaggacgag uucggcguaa ccuggacccu gcaccccgaa agcaacauca     3300

acgacaggau caccuacggc caaguagacg gcaacaaagu cagcaacaaa gucaaacucc     3360

gccccggcaa guacuaccua cuggucuaca aguacagcgg cucaggaaac uacgaacucc     3420

gcgucaacaa guaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  4552
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt8)

<400>  4552
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguca ccuucauaag ccuccucuuu cuguucagca      120

gcgcauacuc aauagccaac accaacucag aaaaauacga cuucgaauac cuaaacggcc      180

uaagcuacac cgaacuaacc aaccucauca aaaacauaaa auggaaccaa auaaacggcc      240

uauucaacua cagcaccggc agucaaaagu ucuucgguga caagaaccgc guccaggcga      300

uaaucaacgc ccuacaagaa uccggccgca ccuacacagc caacgacaug aaaggcauag      360

aaacauucac ggaaguacua cgugcuggau ucuaucuagg cuauuauaac gacggacuga      420

gcuaccuaaa cgacaggaac uuucaagaca aaugcauccc cgccaugaua gcaauccaga      480

aaaaucccaa cuuuaaacuc ggaacggcgg uccaagacga ggugaucacg ucacuuggaa      540

aacucauagg aaacgcgagc gccaacgccg agguaguaaa uaacugcgua ccaguccuga      600

agcaauuccg ugaaaaucuu aaccaauacg ccccagacua cguaaaagga acugcgguca      660

acgagcucau aaaaggaaua gaguucgacu ucagcggagc cgcauaugaa aaagacguaa      720

agaccaugcc cugguacggc aaaauagacc cguucaucaa cgaacucaag gcacuaggcc      780

uauacggcaa caucacaagc gccaccgaau gggccucaga cgucgggauc uacuaccuau      840

caaaauucgg acucuacagc acaaaccgaa acgacaucgu acaaucccua gaaaaagcag      900

ucgacaugua caaauacgga aagaucgcau ucgucgccau ggagcgcauc acgugggauu      960

acgacggaau aggcucaaac ggaaagaaag ucgaccacga caaauuccuc gacgacgcag     1020

aaaaacacua ccugccgaaa acuuauacgu uugacaacgg caccuucauu auccgcgcgg     1080

gcgacaaagu aucugaggaa aagaucaaac gacuauacug ggcuagccga gaaguaaaaa     1140

gccaguucca ccgaguaguc ggaaacgaua aggcgcucga aguaggaaac gccgacgacg     1200

uccuuacuau gaagaucuuc aacagccccg aagaauacaa auucaacacu aacaucaacg     1260

gcguauccac agacaacgga ggccuauaca ucgaaccuag gggcaccuuc uacaccuacg     1320

aacgcacccc acaacaauca aucuucucuc uugaagaacu cuuccggcac gaguacaccc     1380

acuaccuaca agcacgauac cucgucgacg gccuaugggg ccaaggacca uucuacgaga     1440

aaaacagacu caccugguuu gacgaaggga ccgcugaguu cuucgccggc agcacaagaa     1500

caucaggagu ccucccccga aagagcaucc uaggauaccu ggccaaggac aagguagauc     1560

accgcuacag ccuaaagaag acacuaaaca gcggcuacga cgacuccgac uggauguucu     1620

auaauuacgg cuucgcggua gcacacuacc uguaugaaaa agacaugcca accuucauca     1680

aaaugaacaa agcaauacua aacaccgaug ucaaaagcua cgaugaaauu aucaaaaagc     1740

ugagcgacga cgcaaauaaa aacaccgaau aucaaaacca cauccaggaa cucgccgaca     1800

aauaccaagg cgcagggauc ccccuggugu cagacgacua ccuaaaagac cacggcuaca     1860

agaaagccuc ggaagucuac uccgaaauca guaaagcagc cagccuaacc aauacaucag     1920

uuacagccga aaagagccag uacuucaaca cauucacacu gaggggcacc uacacaggcg     1980

aaacuuccaa aggggaguuc aaggacuggg acgaaaugag caagaagcuc gacggcaccc     2040

ucgaaucacu cgcuaaaaau ucauggucgg gauacaagac uuuaacggca uacuucacga     2100

acuaccgagu gacaagcgac aacaaagucc aauacgacgu cgucuuucac ggcguccuga     2160

ccgacaacgc agacauaucc aacaacaaag caccgaucgc aaaagucacc ggaccgagca     2220

ccggggcagu cgggagaaac aucgaguucu caggcaaaga cuccaaggac gaggacggca     2280

aaaucgucag cuacgacugg gacuucggag acggcgcaac aagccggggc aagaacucag     2340

uccacgccua caagaaagca ggaaccuaca acguaacacu aaaaguaacc gacgacaaag     2400

gggcaacagc caccgaaucg uucaccauag aaaucaaaaa cgaagacacc accaccccca     2460

uuacgaaaga gauggaaccg aaugacgaca ucaaagaggc uaacggcccu aucgucgagg     2520

gcguaaccgu aaaaggcgac cuuaacggau cggaugacgc agacaccuuc uacuucgacg     2580

uaaaagaaga uggcgacguc acuaucgagc ucccauacuc cggcuccagc aacuucaccu     2640

ggcucguaua caaggaaggu gacgaccaga accacaucgc uucggggaua gacaaaaaua     2700

acucuaaagu uggcacauuc aagagcacaa aaggccggca uuacguuuuc auauacaagc     2760

acgacuccgc uucaaacauc aguuacagcc ucaacaucaa gggacuggga aaugagaagc     2820

ucaaagagaa agagaacaac gacuccuccg acaaagccac gguaauaccc aacuucaaua     2880

cgaccaugca agguucucua cucggcgacg acagcaggga cuacuacucg uuugagguca     2940

aggaggaagg cgaaguaaac auagagcuug acaagaaaga cgaguucggu gugacgugga     3000

cacuacaccc agaguccaac auaaaugaca gaauaacaua cggccaggua gacggcaaca     3060

aggugagcaa caaagucaaa cuccgacccg guaaauacua ccuauuaguc uacaaauacu     3120

ccggaagcgg gaacuacgag cuacgcguca auaagugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  4553
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt8)

<400>  4553
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguaa ccuucauauc ccuccuguuc cuauucucau      120

cagcauacag caugaagaaa aacauccuca aaauccuaau ggauagcuac ucaaaggaaa      180

guaaaaucca gacgguucgc cgagugacgu ccgucucccu ucuagcagua uaccucacua      240

ugaacacaag cucccuaguc cuggccaaac ccauugaaaa caccaacgac accucuauaa      300

agaacguaga aaaacuccga aacgccccaa acgaggaaaa cucaaagaaa guagaggauu      360

cuaaaaacga caaaguagaa cacgucaaaa acauagaaga ggccaaagua gaacaagucg      420

ccccggaagu caaauccaaa agcacgcugc ggucggcguc ucgccggcga cggaaacgca      480

uagcaaacac aaacucggaa aaauacgacu ucgaauaccu caacggacuc agcuacaccg      540

aacugacgaa ccucaucaaa aacaucaaau ggaaccaaau caacggacug uucaacuacu      600

ccacaggauc ccaaaaguuc uucggcgaca aaaaccgagu acaggcgauc auaaaugccc      660

ugcaggaaag cggcagaacu uauaccgcaa augacaugaa gggcaucgaa acguucaccg      720

agguccugag agcgggcuuc uaccuaggau acuacaacga cggacucagc uaccucaacg      780

accgcaacuu ucaggauaaa ugcauaccgg caaugaucgc aauccagaaa aaccccaacu      840

ucaaacuugg aacagcggua caagaugagg ucaucacauc gcugggaaag cuaauaggaa      900

acgccuccgc aaacgccgaa guagucaaca acugcguccc uguauuaaaa caauuccgug      960

agaaccucaa ccaauacgcc cccgacuacg ucaaaggcac cgccgucaac gaacugauaa     1020

agggcauaga guucgacuuc aguggagcag cauacgaaaa agacgucaag accaugcccu     1080

gguacggcaa aaucgauccc uucaucaaug aacucaaagc gcuuggccuc uacggaaaca     1140

uaaccucugc cacagaaugg gcaagcgacg ucggaauaua uuaccuaucc aaauucggcc     1200

ucuacagcac aaacagaaac gacauaguac agucacucga aaaagcuguc gacauguaca     1260

aauacggaaa gauagcauuc gucgcaaugg aacgcauaac augggacuac gacggcauag     1320

gguccaacgg caagaaagua gaccaugaca aguuccuaga cgacgcagaa aaacacuacc     1380

ugcccaagac cuacaccuuc gacaacggaa ccuucauaau ccgagcaggc gacaaaguaa     1440

gcgaagagaa aauaaaacgc cuauacuggg ccagucgaga agucaaauca caauuccacc     1500

gagucguagg caacgacaag gcacuagaag ugggaaacgc cgacgauguc cuaacuauga     1560

aaaucuucaa cagcccggaa gaauacaaau ucaacaccaa caucaacggg gucucaaccg     1620

acaacggcgg gcuguacaua gagccgcgcg gcacguucua cacguacgag cgcacacccc     1680

aacaaagcau cuuuucgcua gaagaacuuu uccgacacga auauacccac uacuuacagg     1740

cucgauaccu cguagauggc cuauggggcc aaggcccauu cuacgaaaag aacagacuca     1800

ccugguucga cgaaggaacc gcagaguucu ucgcaggauc gaccaggacg agcggcgucc     1860

ucccaaggaa auccauacuu ggauaccucg caaaagauaa gguagaccac cgguacucac     1920

uuaaaaagac ucucaacuca ggauacgacg acuccgacug gauguucuac aacuacggcu     1980

uugccguggc ucacuaucug uacgaaaagg acaugcccac cuucaucaag augaacaaag     2040

ccauccucaa caccgacgua aaaagcuacg acgaaauaau caagaaacuc ucagacgacg     2100

cgaauaaaaa cacagaauac caaaaucaca uacaagagcu cgccgacaaa uaccagggcg     2160

cggggauacc gcucgucucu gacgacuacc ucaaagacca cggguacaag aaagccagcg     2220

aggucuacag ugaaaucagc aaagccgccu cgcuaaccaa caccagcgua acggcggaga     2280

aaagccagua cuucaacacc uucacacuaa gaggaaccua uaccggugag accagcaaag     2340

gcgaguucaa ggacugggac gaaaugucca agaaauuaga cgggacccua gaaucgcugg     2400

ccaaaaacuc cuggaguggg uauaagaccc uuaccgcgua cuucacaaac uacagaguga     2460

ccagcgacaa uaaaguccag uacgaugucg uguuccacgg cgugcuaaca gacaaugcag     2520

acaucucaaa caacaaagcc ccaaucgcca aagucacggg acccagcaca ggcgccguag     2580

gccgcaacau cgaauuuuca gguaaggauu caaaagacga agacggcaag aucgucagcu     2640

acgacuggga cuucggagac ggcgccacca gcagagggaa aaacucagua cacgcguaca     2700

agaaggccgg gaccuacaac gucacccuaa aaguuacgga ugacaaaggc gccacagcca     2760

cggaauccuu caccauagaa aucaagaacg aggacacaac uacccccaua accaaagaga     2820

uggagccaaa cgaugacaua aaagaagcua acggcccaau cguggaaggc guuacuguca     2880

aaggggaccu aaacggcuca gacgacgccg acaccuucua cuuugacgua aaagaagacg     2940

gggacgucac aauagaacuc ccauacuccg gaaguagcaa cuucaccugg cuaguguaca     3000

aggaagggga ugaucaaaac cacauagcau ccggcauaga caagaacaac ucaaaaguug     3060

ggaccuucaa aucgaccaaa ggccggcacu acguauucau cuacaaacac gacuccgcaa     3120

guaauauauc auacagccua aacauaaagg ggcugggaaa ugaaaaacuu aaggaaaaag     3180

aaaacaacga caguagcgac aaagcaacag ugauccccaa cuucaauaca accaugcaag     3240

gcucacuccu cggagaugac ucaagggacu acuacucauu cgaagugaag gaagaaggcg     3300

aagucaacau cgaacucgac aagaaggacg aguucggcgu caccuggacc cuccacccug     3360

aaucaaacau aaacgacagg aucaccuacg gccaaguaga cggaaacaaa gugucaaaca     3420

agguaaaacu cagaccgggg aaauauuacc uacuggugua caaauauucu ggaagcggaa     3480

acuacgaacu acgagucaac aaauagggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  4554
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt8)

<400>  4554
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuca aaauaauccu aaaccgaggc aaaaccauga      120

agcgcaaaug ccucagcaag agacucaugc ucgcaaucac cauggcuaca aucuucacag      180

uuaacucaac ucuccccauc uacgccgcgg uagacaaaaa caacgcaacc gccgccgucc      240

aaaaugaauc uaaacgauac acagucagcu accuaaaaac ccuuaacuac uacgaccucg      300

uagaccugcu cgugaaaacc gaaaucgaga accucccgga ccuguuccaa uauuccagcg      360

augccaaaga guucuacggg aacaaaacac gaaugucguu caucauggac gaaaucggac      420

gccgagcgcc ccaauacacc gagauugauc auaagggaau cccgacgcuc gucgaagucg      480

uccgagccgg guucuaucuc ggcuuccaca acaaggaacu caacgagaua aacaaacgcu      540

cuuucaagga acgcgucaua ccguccauac uugccauaca gaaaaacccc aauuucaagc      600

ucggaacaga aguacaagac aaaaucguau ccgccaccgg ccugcuagcc ggaaacgaaa      660

ccgcaccacc agaagucguc aacaacuuca cucccauccu ucaagacugc aucaagaaca      720

ucgacagaua ugcauuggac gaccuaaaau caaaagcacu guucaacguu cuagccgcgc      780

ccacauauga uauaaccgaa uaccucagag caacaaagga gaaacccgaa aacacucccu      840

gguacggcaa aaucgacggc uucaucaacg aacuaaagaa acucgcauua uacggcaaaa      900

ucaacgacaa caacaguugg aucauagaca acggcauaua ccacaucgcg ccacuaggaa      960

aacuacacuc uaacaacaaa aucggaaucg aaacacuaac cgaagucaug aagguauacc     1020

ccuaccugag caugcaacac cuucaaucug cagaucaaau caaacgacac uacgacagca     1080

aagacgccga gggaaacaag aucccauuag acaaauucaa gaaagaagga aaagagaaau     1140

acugcccaaa gaccuacacg uuugaugaug gcaaaguaau cauaaaggcc ggcgcacgcg     1200

ucgaggaaga aaaagucaaa cgccuguacu gggcgucaaa agaagucaac ucccaauucu     1260

uccgagucua uggcaucgac aaaccccucg aggaaggcaa ccccgacgac auacugacaa     1320

uggucauuua caacucgccu gaggaauaca aacugaacuc agugcuauac ggcuacgaca     1380

ccaacaacgg cggcauguac aucgaacccg aaggcacuuu cuucacuuac gagagagagg     1440

cccaagaauc cacguacaca cuagaagaac uuuuccgaca cgaguacacc cacuaccucc     1500

aaggccguua cgcagucccg ggacaauggg gacgaacgaa acucuacgac aacgacaggc     1560

ugaccuggua cgaagagggc ggggcggaac uauucgcagg gagcaccagg acaucgggga     1620

uacuucccag gaaauccauc gucuccaaca uccacaacac aacacgaaau aaucgguaua     1680

aacugagcga uaccguccac ucaaaauacg gcgcgucauu cgaguucuac aacuacgccu     1740

guauguucau ggacuacaug uacaacaaag auaugggaau ccucaacaaa uuaaacgacc     1800

ucgcuaagaa caacgacgua gacggcuacg acaacuacau aagagaccua uccucaaacu     1860

acgcucugaa cgacaaauac caagaccaca ugcaggaacg aaucgacaac uacgaaaacc     1920

ucaccguccc guucgucgcc gacgacuacc ucgugagaca cgccuacaaa aaccccaacg     1980

aaaucuacag cgagaucagc gaagucgcca aacucaagga cgcaaaaucc gaggucaaaa     2040

agucucaaua cuucagcacc uucacucuac gcggcucaua cacgggcggc gccuccaaag     2100

gcaaauuaga agaccaaaaa gccaugaaca aguuuaucga cgacagccuc aagaaacuug     2160

acaccuacuc guggaguggc uacaaaacuc uaaccgccua cuuuacaaac uacaaagucg     2220

acucguccaa ccgcgugaca uacgacguag ucuuccacgg guaccuaccg aacgagggag     2280

acagcaaaaa cagccucccc uacggaaaaa uaaacggcac auacaaggga accgaaaaag     2340

agaaaauaaa auucuccucc gaaggcucgu ucgaccccga ugguaagaua guauccuacg     2400

aaugggacuu cggagacggc aauaaaagca augaggaaaa cccagaacac ucauacgaca     2460

aaguagggac cuacaccguu aaauuaaaag ucacggacga caaaggagag ucgagcgucu     2520

caaccaccac cgccgagaua aaagaccuau ccgaaaacaa acuacccgua aucuauaugc     2580

acgucccaaa aucaggcgca cucaaucaaa agguugucuu cuauggaaaa ggcaccuacg     2640

acccggacgg cagcauagcg ggcuaccaau gggacuuugg cgacgguucg gacuucucgu     2700

cagagcaaaa cccuagccau guauacacca agaaaggaga auacaccgua acccugcgag     2760

ugauggauuc aucuggccaa augucugaga aaacaaugaa aauaaaaauc accgacccag     2820

uauaccccau cgguaccgaa aaagaaccua acaacaguaa agaaacugca agcggaccca     2880

ucguccccgg cauuccuguc ucaggaacca ucgaaaacac cagcgaucag gacuacuucu     2940

acuuugaugu aaucaccccc ggcgaaguca aaaucgacau caacaaacua ggauacggcg     3000

gagccacaug gguggucuac gacgagaaca auaacgccgu cucuuacgca accgacgaug     3060

gacaaaaccu cagcgguaaa uuuaaagcag acaagcccgg acgcuacuac auccaccuau     3120

acauguuuaa cggcuccuac augcccuauc gaauuaacau ugagggcuca guaggccgcu     3180

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  4555
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt8)

<400>  4555
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaagaaaau gccuauccaa acgccucaug cuugcaauaa      120

caauggccac aauauuuacc gucaacucca cccuaccaau cuacgccgcc guagauaaaa      180

acaacgcaac agcagccguc caaaacgaga gcaaacgaua caccguauca uaccucaaga      240

cccuaaacua uuacgaucua guggaccucc ucguaaagac ggagaucgaa aacuuaccgg      300

aucuauuuca auacuccucc gacgcaaaag aguucuacgg uaacaagaca cgaauguccu      360

ucaucaugga cgaaaucgga cggcgcgcac cccaauacac cgaaaucgac cacaaaggca      420

uacccacccu ugucgaaguu guacgagccg gcuucuacuu aggauuccac aacaaggaac      480

ucaacgaaau caacaaacgc uccuucaaag aacgagucau ccccuccauc cucgcuauuc      540

agaagaaccc aaacuucaag cucgggaccg agguacaaga uaagauaguc agcgccaccg      600

gccugcuggc cggcaaugag accgcgcccc cagagguagu aaacaauuuc accccaaucc      660

uacaagauug caucaagaau aucgaccgcu acgcccugga cgaccuaaaa uccaaggccc      720

ucuucaacgu gcuggccgcg cccaccuacg auaucaccga auaccucaga gcuaccaaag      780

agaaacccga gaacacuccc ugguauggca agauagacgg cuuuauaaac gaacucaaaa      840

agcuagcacu guacggcaag aucaaugaua acaauucaug gaucaucgac aacgggauau      900

accacauugc cccguuaggu aaacugcaca gcaacaauaa aauaggaauc gagacccuaa      960

cugaggucau gaaaguauau cccuaucuua gcaugcaaca ccuacaaucc gcggaccaaa     1020

ucaagcgcca cuacgacagc aaagacgcug aggggaacaa aaucccccug gacaaguuca     1080

agaaagaggg caaggagaaa uacugcccaa aaaccuacac cuucgacgac ggcaaaguca     1140

uaaucaaagc cggcgcgaga guagaggaag aaaaaguaaa gcggcucuac ugggccagca     1200

aagaagucaa cagucaauuc uuccgcgucu acggcaucga uaaaccacua gaagagggaa     1260

aucccgacga cauacuaaca augguaauau acaacagccc agaggaguac aaacugaacu     1320

ccguccuuua cggauacgau acaaacaacg ggggaaugua uauagaaccg gaaggcacau     1380

uuuucaccua cgaacgcgag gcccaggaau caacauauac acucgaggag uuauuccgcc     1440

acgaauacac ccacuaccua cagggacgcu acgcaguacc agggcagugg ggccgcacaa     1500

agcucuacga uaacgaccgc cuaacguggu acgaagaagg gggcgccgaa cucuucgccg     1560

gauccacccg caccagcggg auccuaccgc gaaagaguau agugagcaac auccauaaca     1620

ccacgcgcaa caaccgcuac aagcucucag acacagucca cagcaaguac ggagcaucgu     1680

ucgaguucua caacuacgca uguauguuca uggacuacau guacaacaaa gacaugggca     1740

uccucaacaa acucaacgau cucgcgaaaa auaacgacgu cgacggauac gacaacuaua     1800

uccgcgaccu cucauccaac uacgcacuca acgacaaaua ccaagaccac augcaggaac     1860

gaauagacaa cuacgaaaau uuaaccguac cauucguagc cgacgacuac cuaguacgac     1920

acgccuacaa aaacccuaac gaaaucuacu ccgagaucuc cgaaguugcc aaacucaaag     1980

augccaaauc agaagucaag aaaucccagu acuucagcac auucacucug agaggcagcu     2040

acacgggcgg cgcguccaaa ggaaaacuag aagaucagaa agccaugaac aaauucaucg     2100

acgacucucu aaagaaacuc gacacauacu cguggagcgg uuacaaaaca cugacugccu     2160

acuuuaccaa cuacaaaguc gacaguucaa aucgagucac cuacgacgug guauuucacg     2220

guuaccuacc caacgaaggg gacuccaaaa acucacuacc uuacggaaaa auaaauggga     2280

ccuacaaagg cacagaaaaa gagaaaauca aauucuccuc cgaaggcagc uucgacccug     2340

acggaaagau cgugagcuau gaaugggacu ucggcgacgg caacaaauca aacgaagaaa     2400

accccgagca uucauaugac aagguaggaa ccuacacagu caagcugaaa guaaccgacg     2460

acaaagggga aucaagcgua agcacuacca ccgccgagau caaggacuua agcgaaaaca     2520

aacugccagu aauuuauaug cacgucccaa aaucaggcgc ccuaaaccag aaggugguau     2580

uuuacgguaa agggacguac gaucccgacg gcagcaucgc cggcuaucag ugggacuucg     2640

gugacggcag cgacuucuca agcgaacaaa accccagcca cguuuacacg aaaaagggcg     2700

aauacacagu gacacuuaga gucauggaua gcucggguca aaugagugag aaaacgauga     2760

aaauaaagau caccgacccc guguacccca ucggcaccga aaaggaaccg aacaacucaa     2820

aagaaaccgc cuccgggccc aucguacccg ggaucccugu aucuggcaca auagaaaaca     2880

caagcgacca agacuacuuc uacuucgacg ucauaacccc cggcgaaguc aaaaucgaua     2940

ucaacaaacu cggauacggc ggagcgacau ggguagugua cgacgaaaac aacaacgcag     3000

uauccuacgc cacagacgac ggccaaaacc ucuccggcaa auucaaggcc gacaagcccg     3060

gacgauacua cauacaccuc uacauguuca acggaucaua caugcccuac cggauaaaca     3120

ucgaaggauc ggugggacgg uaaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  4556
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt8)

<400>  4556
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguca cauuuaucag ccuccuuuuc cuuuucagcu      120

cggccuacag cguccaaaac gaaaguaaaa gauauaccgu auccuaucuc aaaacuuuaa      180

acuauuacga ccuaguagac cuccugguaa agacugaaau agaaaaccug ccagaccuau      240

uccaauacag cuccgacgcu aaggaguucu acgggaacaa aacccgcaug uccuucauca      300

uggacgaaau cgggcgacgc gcaccacagu acaccgaaau agaccacaaa gggauuccca      360

cucuagucga ggugguacga gccggauuuu accuuggauu ccacaacaaa gaacucaacg      420

aaauaaauaa gcgaucauuc aaagagcggg uuaucccaag cauacuggca auccaaaaga      480

auccaaacuu caaacuuggc acagaagucc aggacaaaau agucuccgcc accgggcucc      540

ucgccgggaa ugaaaccgca cccccagaag ucgugaauaa cuucaccccc auucuccagg      600

acuguauaaa gaacaucgac cgcuacgcac ucgacgaccu uaagucaaaa gcgcucuuua      660

acguccucgc ggcgccuaca uacgacauca cagaauaccu ucgcgcgacc aaggaaaagc      720

cagaaaacac cccaugguac ggaaaaauag acggguucau caacgaacua aagaaacuag      780

cgcuauacgg caaaaucaac gacaacaaca gcuggaucau ugacaacggc auauaucaca      840

uagcaccccu gggaaaacuc cacagcaaua acaagaucgg caucgaaacc cuaaccgaag      900

uaaugaaagu cuacccguac cucuccaugc agcaucucca gagcgccgac cagauaaaac      960

gacacuacga cucaaaagac gcagaaggua auaagauccc acuggacaag uucaaaaagg     1020

agggcaaaga aaaauacugc ccuaaaacau acaccuucga cgacggaaag guaauaauua     1080

aagccggagc acgaguagaa gaagaaaaag uaaaacgccu cuacugggcc ucaaaggaag     1140

uuaauucaca guucuuccga guguacggua uagacaaacc acuggaggag ggaaacccag     1200

augacauacu gacgauggua auauacaacu ccccggaaga auacaaacua aauucaguac     1260

uguacggaua cgacaccaac aaugggggaa uguacaucga accagaaggc accuucuuca     1320

ccuacgagcg cgaagcccag gagucgacau auacccuaga agaacuguuu cgccacgagu     1380

acacgcacua cuuacaaggg cgcuacgccg uccccgggca guggggccga accaaacugu     1440

acgacaacga ccgccucacc ugguacgaag aagggggagc agaacucuuc gcaggaucga     1500

cccgcaccag cggaauacuc ccccgcaaga guauagucag caacauccac aacaccacca     1560

ggaacaacag auacaaacuu ucagacaccg uucacagcaa guacggggcc uccuucgagu     1620

uuuacaacua cgcaugcaug uucauggauu auauguacaa caaagacaug ggaauacuaa     1680

acaaacucaa ugaccucgcc aaaaacaacg acgucgacgg cuacgacaac uacauccgag     1740

accucagcag caacuacgcc cuaaacgaca aauaucaaga ccacaugcag gagaggauag     1800

auaacuacga aaaucucacc gugccauucg uagccgacga cuaccucgua cgucacgccu     1860

acaaaaaccc caacgaaauc uacagcgaga ucucggaagu agcaaaacua aaagaugcua     1920

aaucagaggu gaagaaaucc caauacuucu cgaccuucac ucuccgcggc uccuacacag     1980

gaggagccag caaagguaaa cuagaggacc aaaaagcaau gaacaaauuc aucgacgacu     2040

cccucaagaa acucgauacc uacagcugga gcggauacaa aacguuaacc gcauauuuca     2100

ccaauuacaa aguggacagu uccaaccgag uaaccuacga uguaguguuc cauggcuacc     2160

uacccaacga gggcgacagc aaaaacucac uccccuacgg aaagaucaac gggacauaca     2220

agggcacgga aaaagagaaa aucaaauuca gcucagaagg cuccuucgac cccgacggca     2280

agauugucuc cuacgagugg gacuucgggg acggcaacaa aucgaacgag gagaacccag     2340

aacacagcua cgacaagguc ggcacguaca ccgucaagcu caaaguaaca gacgacaagg     2400

gggaauccag cguaagcacg acaacagcag aaaucaagga ccuauccgaa aauaaacuac     2460

cggugauaua caugcauguc ccuaaauccg gcgcucugaa ucagaaggug guauucuacg     2520

ggaagggcac guacgacccc gacggaucca uagcaggcua ccaaugggac uucggcgaug     2580

guucggacuu uucguccgag cagaacccaa gccacguaua cacaaagaaa ggggaguaua     2640

ccgucacacu ucgagucaug gacagcagug gccagaugag ugagaaaaca augaaaauca     2700

aaaucacaga ucccguuuac ccgaucggca cagaaaaaga accaaacaau uccaaagaga     2760

cggcgucagg cccaaucgug cccggaaucc ccguuucggg aaccauagag aacacaagcg     2820

accaagacua cuucuacuuc gacgucauca ccccaggcga gguaaaaaua gacauaaaca     2880

aacuaggaua cggaggcgca acaugggugg uauacgacga aaacaacaac gcggucagcu     2940

augcaacgga cgacggccaa aaccuaucag gaaaguucaa ggccgacaag cccggaaggu     3000

acuauauaca uuuguacaug uucaacggca gcuacaugcc cuacagaauc aacaucgaag     3060

gcagcgucgg ccgcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4557
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt8)

<400>  4557
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguga ccuucauauc acuccuuuuc cuauucucau      120

cagcauacuc gaugaaacgc aaaugccuca gcaaacgacu caugcuagcu aucaccaugg      180

ccacaauauu caccguaaac uccacccuac ccaucuacgc ggcaguggac aaaaacaacg      240

ccaccgccgc acgucgccgc cggaaacgcg uccaaaacga aaguaagcgc uauacgguga      300

gcuaccucaa aacucucaac uacuaugauc uaguagaccu ccuagucaaa acggaaauug      360

aaaaccuccc cgaccuauuc caguacucau cagacgcgaa agaguucuac ggcaacaaaa      420

cccggauguc cuucauaaug gacgaaaucg gaaggcgagc accccaguau accgagaucg      480

accacaaggg cauccccacg cucguagaag uaguuagagc aggcuucuac cucggguucc      540

acaacaaaga acuaaaugag aucaacaaac gcuccuucaa agaacgcguc auccccucaa      600

uacuagcaau ccagaaaaac cccaauuuca aacuaggcac cgagguacaa gauaaaaucg      660

uguccgcaac aggccuccug gcagguaaug aaaccgcgcc gccagaagua gucaacaacu      720

ucacacccau ccuucaggac ugcaucaaaa acauagacag auacgcacuc gacgaccuca      780

aaagcaaagc acuauucaac guccucgcag cacccacaua ugacauaacg gaauaccuua      840

gagcaaccaa agaaaaaccc gaaaacacac ccugguaugg gaaaauagac ggcuucauca      900

acgagcuuaa aaagcuggca cuuuacggga aaauaaacga caacaacagc uggaucauag      960

acaacggcau uuaccacauc gcaccccugg ggaaauugca cagcaacaac aaaaucggca     1020

uagaaacccu cacggagguc augaaaguuu acccauaccu gucaaugcaa caccuccaau     1080

ccgccgacca gaucaaacga cacuacgaca gcaaagacgc cgaaggcaac aagauaccac     1140

uagacaaguu caagaaagaa ggcaaagaaa aauauugccc uaaaaccuac acauucgacg     1200

acggaaaagu aaucauuaaa gccggcgccc guguagaaga agaaaagguc aaacgccuau     1260

acugggccag caaagaagua aauagccaau ucuuccgcgu auacgggaua gacaaaccgc     1320

uagaagaagg aaaccccgac gacauacuga ccaugguaau auauaacuca ccggaagaau     1380

acaaacucaa cagcguacua uacggcuaug acaccaauaa cggaggaaug uacaucgagc     1440

cagaaggaac auucuucacg uacgaacgug aagcacaaga auccacauac acccucgagg     1500

aacucuuccg ucacgaguac acccacuacc uacaggggcg auacgccgua cccggccaau     1560

ggggccgcac caaacuguau gacaacgacc ggcucaccug guacgaagaa gggggcgccg     1620

aacucuucgc cgguucgacc aggacuucag gaauacugcc ccgcaagagc aucguaagca     1680

acauccacaa uacaacccgc aacaaccgcu acaaacuauc agacacaguc cacuccaaau     1740

acggagcguc auuugaguuc uacaacuacg cuugcauguu uauggauuau auguacaaca     1800

aagauauggg gauccugaau aaacuaaacg accuagcgaa aaacaacgac guugacggcu     1860

acgacaacua cauacgugac cucucaucaa acuacgcccu aaacgacaaa uaccaggacc     1920

acaugcaaga acgcaucgac aauuacgaaa accuaacagu gccuuuuguc gccgacgacu     1980

accucguacg gcacgcuuac aaaaacccca acgaaaucua uucagaaauc ucagaagucg     2040

ccaaauuaaa agacgcuaaa uccgaaguca agaaguccca auacuucucc acauuuaccc     2100

ucagaggcuc auacaccgga ggcgcaucca aaggcaaacu ggaggaccaa aaagccauga     2160

acaaauucau cgaugacagu cuaaagaaac ucgacaccua cuccuggucc ggauacaaaa     2220

cgcuaacagc cuacuucaca aacuacaaag uagacagcuc caaccgaguc accuacgacg     2280

ucgucuucca ugguuaccuc cccaacgaag gugacagcaa aaauucacuc cccuacggca     2340

aaauaaacgg caccuacaaa ggcaccgaaa aggagaaaau caaauucuca ucggaaggca     2400

gcuucgaccc agacgggaag auaguaucgu augaauggga cuucggggac ggcaacaaau     2460

ccaaugaaga gaaccccgaa cauuccuaug acaaaguggg gaccuacaca guuaagcuaa     2520

aaguaaccga cgacaaaggc gaaucauccg uaucaaccac aacggccgag auaaaagauc     2580

uaagcgaaaa caaacucccc guaauauaca ugcacguccc uaaaucggga gcucucaacc     2640

aaaaagucgu auucuacgga aaaggaacau acgacccuga cggcuccaua gccggcuacc     2700

aaugggacuu uggcgacggc agcgacuucu ccagugagca aaaccccuca cacgucuaca     2760

cgaaaaaggg cgaauacacc gugacacuuc gcguaaugga cagcagcggc cagauguccg     2820

agaaaaccau gaaaaucaag auuaccgacc cagucuaccc cauaggcacc gaaaaggaac     2880

cgaacaauag caaggaaaca gccagcggcc caauaguccc ggggaucccc gucuccggca     2940

cgaucgaaaa cacuuccgac caggacuacu ucuacuucga cguaauaacc cccggcgaag     3000

uaaaaaucga caucaacaaa cuaggauacg gaggcgccac cugggucguc uacgaugaaa     3060

acaacaacgc cguauccuau gccacagacg auggccagaa cuugucaggc aaguucaaag     3120

cugacaagcc cggacgcuac uacauccacc uguacauguu caauggcucc uacaugccau     3180

accgaauaaa caucgaagga ucggucggac gcugaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  4558
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt8)

<400>  4558
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuauucgc augccuccuc ggagccgccu      120

ucgccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc ucuuacgaag      180

uccucacccc ccuaaaaugg uaccaaucaa uucgcccccc cuauccaucc uacggcuacg      240

aacccauggg cggcuggcua caccaccaaa uaauacccgu ccucucccaa caacaccccc      300

ccacccacac ccuccaaccc caccaccaca uccccgucgu ccccgcacaa caacccguca      360

ucccccaaca accaaugaug ccagucccag gccaacacuc uaugaccccc auccaacacc      420

accaacccaa ccuccccccc cccgcacaac aaccauacca accccaaccc guccaaccac      480

aaccccacca acccaugcaa ccccaacccc ccguccaccc caugcaaccc cucccacccc      540

aaccaccccu cccccccaug uuccccaugc aaccccuccc ccccaugcua cccgaccuaa      600

cccucgaagc cuggcccucc acagacaaaa caaaacgaga agaagucgac uaaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  4559
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt8)

<400>  4559
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccucccac cccaccccgg ccaccccgga uacauaaacu      120

ucuccuacga aguccuaaca ccccuaaaau gguaccaauc cauacgccca cccuaccccu      180

ccuacggcua cgaacccaug ggcggauggu aaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  4560
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt8)

<400>  4560
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccucccac cccaccccgg ccaccccggc uacauaaacu      120

ucuccuacga aguccucaca ccacucaaau gguaccaauc cauccgccca ccacccaugc      180

uccccgaccu cacccucgaa gccuggcccu ccaccgacaa aacaaaacgc gaagaagucg      240

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  4561
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt8)

<400>  4561
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg caccccgaac ccuaguccua cuccuauccg      120

gcgcccuagc ccucacccaa accugggcca ugccacuacc accccaccca ggccaccccg      180

gcuacaucaa cuucuccuac gaaguacuca caccacuaaa augguaccaa uccauccgac      240

cacccuaccc cuccuacggc uacgaaccca ugggcggcug guaaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  4562
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt8)

<400>  4562
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccguaaugg caccccgaac acucguacuc cuccucuccg      120

gagcacuagc ccucacccaa accugggcca ugccccuccc cccacacccc ggccaccccg      180

gcuacauaaa uuucuccuac gaaguccuca ccccccucaa augguaccaa uccauccgcc      240

ccccccccau gcuccccgac cuaacacucg aagccuggcc cucaaccgac aaaacaaaac      300

gcgaagaagu cgacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  4563
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt8)

<400>  4563
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuauucgc augccuaguc ggcgccgccu      120

ucgccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uacucacccc acucaaaugg uaccaaucca ugauacgccc acccuacucc uccuacggau      240

acgaacccau gggcggcugg cuccaccacc aaauaauccc cgucguuucc caacaacacc      300

cccucaccca cacccuccaa ucacaccacc acauccccgu aguccccgcc caacaacccc      360

gaguccgcca gcaagcccuc augcccguac caggccaaca aucaaugacc cccacccaac      420

accaccaacc caaccucccc cuccccgccc aacaacccuu ccaaccccaa cccguccaac      480

cccaaccaca ccaaccaaug caaccccaac cacccgucca acccaugcaa ccccuucucc      540

cccaaccucc ccuaccaccc auguuccccc uccguccucu cccacccauc cuccccgacc      600

uccaccucga agccuggccc gccaccgaca aaaccaaaca agaagaagua gacugaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  4564
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt8)

<400>  4564
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuaccac cccaccccgg ccaccccggc uacauaaacu      120

ucuccuacga aguccucacc ccacucaaau gguaccaauc aaugauacga ccacccuacu      180

ccucauacgg cuacgaaccc augggcggcu gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4565
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt8)

<400>  4565
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cacaccccgg ccaccccggc uacauaaacu      120

ucuccuacga aguccuaaca ccacucaaau gguaccaauc caugauccgc ccccccccca      180

uacuccccga ccuccaccuc gaagccuggc ccgccacaga caaaaccaaa caagaagaag      240

ucgacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4566
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt8)

<400>  4566
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccacgcac acucguccuc cuacucucag      120

gagcccucgc acucacacaa accugggcca ugccacuccc accacacccc ggccaccccg      180

gcuacaucaa cuucucauac gaaguccuca ccccacucaa augguaccaa ucaaugauac      240

gcccacccua cuccuccuac ggcuacgaac ccaugggcgg augguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4567
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt8)

<400>  4567
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagucaugg caccccgcac ccucguccua cuacucuccg      120

gcgcccucgc ccucacccaa acaugggcca ugccacuccc accccacccc ggacaccccg      180

gcuacaucaa cuucucauac gaaguccuca ccccacucaa augguaccaa uccaugaucc      240

gacccccacc cauccuaccc gaccuccacc ucgaagccug gcccgccacc gacaaaacca      300

aacaagaaga agucgacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4568
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt8)

<400>  4568
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc augccuccuc ggcgccgccu      120

ucuccaugcc ucuaccaccc caccccggcc accccggcua cauuaacuuc uccuacgaag      180

uccuaacucc ccuaaaaugg uaccaaaaca ugauccgaca ccccuacacc uccuacggau      240

acgaacccau gggcggaugg cuccaccacc aaaucauccc cgucgucucc caacaaacac      300

cccaauccca cgcccuacaa ccccaccacc acauccccau gguacccgcc caacaacccg      360

guauacccca acaacccaug augccccucc ccggccaaca cucaaugacc cccacccaac      420

accaccaacc caaccuaccc cuacccgcac aacaacccuu ccaaccccaa ccaguccaac      480

cccaacccca ccaaccacuc caaccccaau cccccaugca ccccauccaa ccccuccucc      540

cacaaccacc ccucccaccc auguucucca ugcaaucacu ccuccccgac cucccccucg      600

aagccuggcc cgcaaccgac aaaaccaaac gcgaagaagu cgacuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4569
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt8)

<400>  4569
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuaccac cccacccagg ccaccccggc uacaucaacu      120

ucuccuacga aguccucaca ccacucaaau gguaccaaaa caugaucaga cacccauaca      180

ccucauacgg cuacgaaccc augggcggcu gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4570
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt8)

<400>  4570
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuacccc cacaccccgg ccaccccggc uacauaaacu      120

ucucauacga aguacucacc ccacucaaau gguaccaaaa caugauccga caccccuccc      180

uccuccccga ccucccccuc gaagccuggc ccgccaccga caaaaccaaa cgcgaagaag      240

ucgacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4571
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt8)

<400>  4571
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagucaugg caccccgcac acucguccuc cuacuaucag      120

gagcccucgc acucacacaa acaugggcca ugccccuacc accccacccc ggacaccccg      180

gcuacauaaa cuucuccuac gaaguccuaa caccccuaaa augguaccaa aacaugaucc      240

gacaccccua caccuccuac ggcuacgaac ccaugggcgg cugguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4572
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt8)

<400>  4572
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccacgcac ccuaguccuc cuccuauccg      120

gcgcacucgc acucacacaa accugggcca ugccccuccc accacacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca caccccucaa augguaccaa aacaugaucc      240

gccacccauc acuccuccca gaccucccac ucgaagccug gcccgccacc gacaaaacca      300

aacgcgaaga aguagacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4573
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt8)

<400>  4573
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uacucuucgc augccuccuc ggcgccgccu      120

ucuccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc uccuacaucc      180

gccacccaua caccuccuac ggcuacgaac ccaugggcgg cuggcuacac caccaaauca      240

uccccgucgu cucccaacaa acaccccaau cccacgcccu acaaccccac caccacaucc      300

caaugguccc cgcccaacaa ccaggcaucc cacaacaacc caugaugccc cuacccggcc      360

aacacucaau gaccccaacu caacaccacc aacccaaccu accccuaccc gcccaacaac      420

ccuuccaacc ccaacccguc caaccccaac cccaccaacc ccuccaaccc caauccccca      480

ugcaccccau ccaaccccuc cuaccccaac caccccuccc acccauguuc ucaaugcaau      540

cccuacuccc cgaccuaccc cucgaagcau ggcccgcuac agacaaaaca aaacgcgaag      600

aagucgacua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  4574
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt8)

<400>  4574
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaccugga ucuucuucgc cugccuccuc ggcgccuccc      120

ucgcaaugcc ccucccaccc caccccggcc accccggcua caucaacuuc uccuaugaag      180

uacucacacc ccucaaaugg uaucaaaaca ugauccgcca ccccuacaca uccuacggcu      240

acgaacccau gggcggcugg cuacaccacc aaaucauacc cgucgucuca caacaaacac      300

cccaaucaca cgcccuccaa ccccaccacc acauccccau gguccccgcc caacaacccg      360

gcauccccca acaacccaug augccccuac caggacaaca cuccaugacc ccaacccaac      420

aucaccaacc uaaucucccc cuccccgccc aacaacccuu ccaaccccaa cccguccaac      480

cccaacccca ccaaccccuc caaccccaau cccccaugca cccuauccaa ccccuccucc      540

cccaaccacc ccucccaccc auguucucca ugcaaucacu ccuacccgac cucccccucg      600

aagccuggcc ugccaccgac aaaacaaaac gcgaagaagu cgacuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4575
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt8)

<400>  4575
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uacucuucgc cugccuccuc ggcgccgcau      120

ucucaaugcc ccucccacca cacccaggcc accccggaua caucaacuuc uccuacgaag      180

uacucacccc acucaaaugg uaccaaaaca ugauccgaca ccccucacuc cuccccgacc      240

ucccccuaga agccuggcca gccaccgaca aaaccaaacg cgaagaaguc gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  4576
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt8)

<400>  4576
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccua ggcgcugccu      120

ucuccaugcc acucccaccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

accuauaccu cgaagccaua cgcaucgacc gcaccgcauu uguccuaacc ccacucaaau      240

gguaccaaaa caugauccga cacccauaca ccuccuacgg cuaugaaccc augggaggcu      300

ggcuacacca ccaaaucauc ccagucgucu cacaacaaac cccucaaucu cacgcccucc      360

aaccacacca ccacaucccc augguccccg cccaacaacc cggcaucccc caacaaccca      420

ugaugccccu ccccggccaa cacuccauga cccccaccca acaccaccaa cccaaccucc      480

cccuccccgc acaacaaccc uuccaacccc aaccagucca accccaacca caccaacccc      540

uucaacccca aucccccaug caccccaucc aaccccuccu accacaacca cccuuaccuc      600

ccauguuuuc uaugcaaucc cuccuccccg accucccccu cgaagccugg cccgccaccg      660

acaaaacaaa acgcgaagaa guagacuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  4577
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt8)

<400>  4577
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaccugga uccuauucgc cugccuccua ggagccgccu      120

ucucaaugcc ccuaccaccc caccccggcc accccggcua caucaacuuu uccuacgaag      180

uccucacccc acucaaaugg uaccaaaaca ugauacgcca ccccacaccc caaucccacg      240

cccuacaacc ccaccaccac auccccaugg uccccgccca acaacccggc aucccccaac      300

aacccaugau gccccucccc ggccaacacu ccaugacccc cacccaacac caccaaccca      360

accucccccu ccccgcccaa caacccuuuc aaccccaacc cguccaaccc caaccacacc      420

aaccacucca accccaaucc cccaugcacc caauccaacc ccuccucccc caaccacccc      480

ucccacccau guucucaaug caaucacuac uccccgaccu cccccucgaa gccuggcccg      540

ccaccgacaa aaccaaaaga gaagaagucg acuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  4578
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt8)

<400>  4578
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucucccac cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucaca ccccucaaau gguaccaaaa caugauccgc caccccuaca      180

ccucauacgg cuacgaaccc augggcggcu ggcuccacca ccaaaucauc cccgucgucu      240

cccaacaaac accccaauca cacgcacucc aaccccacca ccacaucccc augguccccg      300

cccaacaacc cggcaucccc caacaaccca ugaugccacu ccccggccaa cacucaauga      360

cccccaccca acaccaccaa cccaaccucc cacuccccgc acaacaaccc uuccaaccac      420

aacccguaca accccaaccc caccaaccac uccaacccca aucccccaug caccccaucc      480

aaccccuacu cccccaacca ccccuacccc caauguucuc aaugcaaucc cuccuccccg      540

accucccccu cgaagcaugg ccagccacag acaaaaccaa acgcgaagaa gucgacuaag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  4579
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt8)

<400>  4579
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaggcguug caagacuacc acuacucuua ggacuacuac      120

uacuaccgcg accaggacga ccccucgacc uagcagacua caccuaugac cucgccgaag      180

aagaugauag cgaaccgcua aauuacaaag acccguguaa agcagcagcu uuucuaggcg      240

acauagcccu ggacgaggaa gaccuucggg cguuccaagu acaacaggca guagauuuac      300

gccgacacac ggcucgaaaa ucaucaauca aagcagccgu uccaggaaac acgucaaccc      360

caagcuguca gucaacaaau gggcaacccc aacgcggagc gugcggacga uggcgaggcc      420

gcagcagguc ccgcagagca gccaccuccc gccccgaaag agucuggccc gauggaguaa      480

uaccguucgu aauaggcggc aauuucaccg gaucccagcg cgcggucuuc cgccaagcca      540

ugagacacug ggagaaacau accugcguga cauuccucga aagaacagac gaagacucau      600

acauaguauu caccuaccga ccgugcggcu gcugcagcua cguaggccgc agaggcggcg      660

ggccacaagc gaucagcauc ggcaaaaacu gcgacaaauu cggaauaguc guccacgaac      720

ucggccacgu aguaggcuuc uggcacgagc acacccgacc ugaccgagac cgacacguca      780

gcaucguaag agaaaacaua caaccagggc aagaauacaa cuuccugaaa auggagcccc      840

aagaagugga auccuuagga gaaaccuacg acuuugacuc aaucaugcac uacgcaagga      900

acacauucuc acgaggaaua uuccucgaca caauaguucc caaguacgaa gugaacgggg      960

uuaaaccucc gauuggccaa aggacaagac uaucaaaggg cgacaucgca caggcacgaa     1020

aacuguacaa augccccgca ugcggggaga cacuacaaga cagcaccggg aacuucucaa     1080

guccggaaua cccaaacgga uacagugcuc acaugcacug cguauggcgg auaagcguca     1140

ccccgggcga gaaaauaaua cuaaacuuca caagucugga ccuauaccgg agccgccuuu     1200

gcugguacga uuacguagaa guccgcgacg gauucuggcg caaagcgcca cugaggggac     1260

gcuucugcgg aucaaaacuc ccggaaccga uaguaucaac cgacucacgc cucugggucg     1320

aguucagaag cagcucaaac ugggucggaa aaggauucuu ugcaguguac gaagcuaucu     1380

gcggaggaga cguaaagaaa gacuaugggc acauacaaag ccccaacuac cccgacgacu     1440

accgcccuag caaaguuugc aucuggcgca uacaagucag cgaaggcuuc cacgucggcc     1500

ugacauucca gaguuucgaa auagaacgcc augacagcug cgccuacgau uaccucgaag     1560

uccgcgacgg ccacucggaa agcagcaccu uaaucggcag guacugcggu uacgaaaaac     1620

cagacgacau aaagagcacc ucgagccgac ucuggcuaaa auucguaagc gacggcagca     1680

uaaacaaagc gggcuuugca guuaacuucu ucaaagaagu ggacgaaugc uccaggccaa     1740

accgaggcgg gugcgaacaa agaugucuaa auacacucgg cagcuacaaa ugcagcugcg     1800

acccgggaua cgaacucgcc cccgacaaaa gaaggugcga agccgccugc ggaggguucc     1860

ucacaaaacu aaacgggagc aucacuucac cgggauggcc aaaagaauac ccaccaaaua     1920

agaacugcau cuggcaacuc gucgcaccca cccaauaccg caucagccua caauucgacu     1980

ucuucgaaac cgaaggcaac gacgucugca aauacgacuu cguugaaguc cgcuccggac     2040

uaacagcaga cagcaaacua cacgguaaau ucugcggcuc cgaaaagcca gaagucauaa     2100

caagccaaua caacaauaug agagucgagu ucaagagcga caacaccguc agcaaaaagg     2160

gauuuaaggc acacuucuuc ucagacaaag acgaaugcuc aaaagacaac ggcggcugcc     2220

aacaagacug cguuaacaca uucggcucau acgaaugcca augcagauca gguuucgugc     2280

ugcacgacaa caaacacgac ugcaaagaag ccggcugcga ccauaaaguu accagcacca     2340

guggaaccau aacaagcccc aacuggccag acaaauaccc aucgaagaaa gaaugcacgu     2400

gggcuaucuc cagcacaccc gggcaccggg ucaaacucac cuucauggaa auggauaucg     2460

aaagccaacc ggaaugcgca uacgaccauc uagaagucuu ugacggccga gacgccaaag     2520

ccccaguacu cggcagauuc ugcggaucca agaaaccaga accaguacuc gcgaccggga     2580

gccgaauguu ccuccgcuuc uacagcgaca acuccgugca acgcaaaggc uuccaagccu     2640

cccaugcgac ggaaugcggc ggacaaguuc gcgcggacgu caaaaccaaa gacuuauaca     2700

gccaugcaca guucggugac aacaauuacc ccggaggcgu agacugcgaa ugggucauag     2760

uagccgaaga aggauacggc gucgagcucg uauuccagac auucgaagua gaagaagaaa     2820

ccgacugcgg cuacgauuac auggaacuuu ucgacgggua cgacagcaca gcgccacgcc     2880

ucggacgcua cugcggauca ggcccgccag aagaaguaua cagcgcaggc gacuccgucc     2940

uagucaaauu ccauucugau gacaccauca caaagaaagg cuuccacuug agauacacaa     3000

guacaaaauu ccaagacacc uuacauucaa gaaaauaagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  4580
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt8)

<400>  4580
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgccggaa cucgcugccu ccuagcccuc cuacuccccc      120

aaguacuacu cggcggcgcc gccggccucg uucccgaacu cggacgacga aaauucgccg      180

ccgcauccuc uggaaggccc agcucccaac ccuccgacga aguucucucc gaguucgaac      240

uccgccuccu cucaauguuc ggccucaaac aacgccccac accaucacgc gacgcagucg      300

ucccgcccua caugcucgac cuauaccguc gucacucagg ccaacccgga ucccccgccc      360

ccgaccaccg ucucgaacgc gcagccucgc gcgccaacac aguccgcucc uuccaccacg      420

aagaaucccu cgaagaacua cccgaaaccu ccggcaaaac aacccgacgc uucuucuuca      480

accucagcuc cauccccaca gaagaguuca uaaccuccgc cgaacuacaa guauuccgcg      540

aacagaugca agacgcccuc ggaaacaaca gcucauucca ccacagaauc aacauuuacg      600

aaauaaucaa acccgccacc gcgaacagca aauuucccgu cacccgucuc cucgacaccc      660

gccucgucaa ccaaaacgcc ucccgcuggg aaucuuuuga cguaacaccc gcagucaugc      720

gcuggacagc acaaggccac gccaaccacg gauucgucgu agaaguagcc caccuagaag      780

aaaagcaagg aguauccaaa cgucacguac gaauaucacg cucccuacac caagacgaac      840

acuccugguc ccaaauccga ccccuacucg ucaccuucgg ccacgacgga aaaggacacc      900

cccuucacaa aagggaaaaa cgccaagcca aacacaaaca acgcaaacga cucaaauccu      960

caugcaaaag acacccccuc uacguugauu ucucagacgu cggcuggaac gacuggaucg     1020

uagccccacc cggcuaccac gccuucuacu gccacggcga augccccuuc ccccucgcag     1080

accaccuuaa uucaaccaac cacgcaaucg uccaaacccu cgucaacucc gucaacucaa     1140

aaauccccaa agccugcugc guccccaccg aacuaucagc caucuccaug uuauaccuag     1200

acgaaaacga aaaagugguc cucaaaaacu accaagacau ggucgucgaa gguugcggcu     1260

gccgauaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  4581
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt8)

<400>  4581
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auacccggca accgcaugcu cauggucguc cuccucugcc      120

aaguacuccu cggaggagcc ucacacgccu cacucauacc agaaacuggc aaaaaaaaag      180

ucgcugaaau ccaagggcac gccggcggcc gccgcuccgg ccaaucccac gaacuucuua      240

gagacuucga agccacccua cuccaaaugu ucggacuccg ccgccgcccc caacccucca      300

aaucugcagu uauacccgac uacaugcgcg accuauaccg ucuacaauca ggcgaagaag      360

aagaagaaca aauccauagu accggccucg aauaccccga acgccccgcc ucccgcgcaa      420

auacaguccg cucauuccau cacgaagaac accucgagaa cauccccgga acguccgaaa      480

acuccgccuu ccgauuccuc uucaaccuau cauccauccc cgaaaacgaa gucaucuccu      540

ccgccgaacu ccgccuuuuc cgcgaacaag ucgaccaagg ccccgacugg gaacgcggcu      600

uccaccgcau aaacaucuac gaaguaauga aaccacccgc cgaggucguc cccggacacc      660

uuaucacacg ccuccucgac acccgacuag uccaccacaa cgucacccga ugggaaaccu      720

ucgacguauc ccccgcaguc cuccgcugga cccgcgaaaa acaacccaac uacggacucg      780

ccauagaagu uacacaccuc caccaaaccc gaacacacca aggccaacac guccgaaucu      840

cccgcucccu cccacaaggc uccggcaacu gggcccaacu ccgcccccuc cucguaaccu      900

ucggacacga cggacgcgga cacgcccuca cccgacgccg ccgagccaaa cgcuccccca      960

aacaccacuc acaaagagcc aggaaaaaaa auaaaaauug ccgccgccac ucacucuacg     1020

uagacuucag cgacgucggc uggaacgacu ggauagucgc cccccccggc uaccaagcau     1080

ucuacugcca uggcgacugc cccuucccac ucgccgauca ccuaaacagc accaaccacg     1140

ccauagucca aacccuagua aacuccguca acuccagcau acccaaggca ugcugcguac     1200

ccacagaacu gagcgcaauc uccauguuau accucgacga auacgacaaa guaguacuca     1260

aaaacuacca agaaauggua guagaaggau gcggcugccg cuaaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  4582
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt8)

<400>  4582
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggauuag gucgccgagc acaguggcuc ugcugguggu      120

ggggacuccu cuguagcugc ugcggacccc ccccccuacg cccaccucuc cccgccgcug      180

ccgccgccgc cgccggcggc caacuacucg gagacggcgg aucacccggc cgaacugaac      240

aaccaccccc cucaccccaa uccucaagcg gguuccucua ccgucgccug aaaacccaag      300

aaaaacgcga aaugcaaaaa gaaauccuau ccguccucgg ccucccccac cgcccccgcc      360

cccuacacgg acugcaacaa ccccagccac cagcccuacg ucaacaagaa gaacagcagc      420

aacaacaaca auuaccaaga ggagaaccac ccccuggccg acugaaaucc gccccacuau      480

ucaugcucga ccuauacaac gcacucagcg cagacaauga cgaagacggc gcaucagaag      540

gagaaagaca acaaucaugg ccacacgaag cagccucaag cucccaacga agacaaccac      600

cacccggagc agcgcacccc cuaaaccgca aaucccuacu ggcccccgga uccggcagcg      660

gcggcgccuc cccacuaacc agcgcccaag acucugcauu ccuuaacgac gcagacaugg      720

ucaugucauu cguuaaccug gucgaauacg acaaagaauu cucgccccga caacgacauc      780

acaaggaauu caaauucaac cucagccaga uacccgaagg cgaaguaguc accgccgccg      840

aguuccgcau cuauaaagac ugcgucaugg gaucauucaa aaaccaaaca uuccuaaucu      900

ccaucuacca aguacuccaa gaacaccagc accgcgacag cgaccucuuc cuauuagaca      960

cccgcguagu cugggccuca gaagaaggcu ggcucgaauu cgacauaacu gccaccucaa     1020

aucuuugggu cgucacacca caacacaaca ugggccucca acucuccgua gucacccgug     1080

acggagucca cguacacccc cgagcugccg gccucgucgg acgagacggc cccuacgaca     1140

aacaacccuu cauggucgca uucuucaaag ucuccgaagu ccacguccga accacccgcu     1200

cagccuccuc ccgucgcagg caacaauccc gaaaccgauc cacacaaucc caagauguag     1260

ccagaguauc cuccgccucc gacuauaacu ccuccgaacu caaaacagca ugccgcaaac     1320

acgaacucua uguauccuuc caagaccuug gauggcaaga cuggaucauc gccccaaaag     1380

gauacgccgc caacuacugc gacggcgaau guucauuccc ucuaaacgcc cacaugaacg     1440

caaccaacca cgccaucgua caaacacuug uccaccucau gaaucccgag uacgucccca     1500

aacccugcug cgcacccacc aaacucaacg ccauaucagu cuuauacuuc gacgacaacu     1560

caaacguaau ccugaaaaaa uaccgcaaca uggucguucg cgcaugcggc ugccacuaag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  4583
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt8)

<400>  4583
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacguccguu cccugagagc cgccgccccc cacucguuug      120

ucgcccuaug ggcaccccua uuccuccuuc gaucagcacu ugcagacuuc ucccuugaca      180

acgaagucca cucguccuuc auccaccgcc gccucagauc acaagaacga cgagaaaugc      240

aacgcgaaau acuuagcauc cuaggccucc cccaccgucc ccgaccacau cuccaaggca      300

aacacaacuc agccccaaug uucaugcucg accucuacaa cgccauggcc gucgaagagg      360

gcggcggacc cggcggucaa ggcuucuccu acccauacaa agccgucuuc agcacucaag      420

gaccaccccu cgcuucccuu caagacuccc acuuccuaac cgacgcagau auggucaugu      480

ccuucgucaa ccuagucgag cacgacaaag aauucuucca cccccgcuac caccaccgag      540

aauuccgcuu cgaccucucc aaaauacccg aaggcgaggc cgucacagcu gccgaauucc      600

gcaucuacaa agacuacauc cgcgaacgcu ucgacaacga aaccuucagg aucucagucu      660

aucaaguccu acaagaacau cucggccgcg aauccgacuu auuccuccua gacucacgca      720

cccucugggc cucagaagaa ggauggcucg uauucgacau cacagccaca ucaaaccacu      780

gggucgucaa cccccgccac aaccucggcc ugcagcuauc aguagaaacc cucgacggac      840

aauccaucaa ccccaaacuc gccggucuca ucggccgaca cggcccacaa aacaaacagc      900

ccuucauggu cgccuucuuc aaagccaccg aaguccacuu ccgaagcauc cgcuccaccg      960

gauccaaaca acgcucccag aaucguucca aaaccccgaa aaaccaagag gcccuacgca     1020

uggccaacgu cgcagaaaac uccucaucag accaacgcca agccugcaaa aaacacgaac     1080

uauacgucuc cuuccgcgac cucggauggc aagacuggau caucgcacca gaaggcuacg     1140

ccgccuacua cugugaagga gaaugcgccu uuccucucaa cuccuacaug aacgccacca     1200

accacgcaau uguacaaacc cuaguucacu ucaucaaccc agaaacaguc ccaaaacccu     1260

gcugugcccc cacacaacua aacgcaauau ccguccucua cuucgacgau uccucgaacg     1320

uuauccucaa aaaauaccgc aacaugguag uccgagccug cggaugccac ugaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  4584
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt8)

<400>  4584
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagccucag ccgcccuccu cugccuccuc cucacagcag      120

ccgccuucuc cccccaaggc cucgcccaac cagucggcau caacaccucc acaaccugcu      180

gcuaccgcuu cauaaacaaa aaaauaccca aacaacgccu agaauccuac cgcagaacca      240

cauccucaca cugcccccgc gaagccguca ucuucaaaac caaacuagac aaagaaaucu      300

gcgccgaccc cacccaaaaa uggguccaag acuucaugaa acaccuagac aaaaaaacac      360

aaacccccaa acucuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  4585
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt8)

<400>  4585
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuguuaacgc uaaucauccu acuaccaguc guaagcaagu      120

ucucuuuugu cucccugagc gcgccccagc auugguccug cccagaaggc acccucgcag      180

gcaauggaaa cagcacaugc guaggcccgg cuccauuccu aaucuucagc cauggcaaca      240

gcaucuuuag aaucgacacc gagggcacca acuacgaaca acucguggua gaugccggag      300

ugagcguaau aauggacuuc cacuacaacg aaaaacgcau auauuggguc gaccuagaac      360

ggcagcuccu ccaaagggua uuucucaacg gaucccgaca ggagcgggug ugcaauaucg      420

agaaaaacgu cuccggaaug gcaaucaacu ggaucaacga agaagucauc uggagcaauc      480

agcaggaagg aaucauaaca gucacugaua ugaagggcaa uaacucccac auacuacucu      540

cagcacuaaa auaccccgcc aacguagcag uagauccugu ggaacgcuuc aucuucugga      600

gcucagaggu agccgguagc cucuacagag cggaucuuga cggagugggu gugaaagcac      660

uuuuagaaac aagcgagaaa auaaccgcag uaucccuuga cgugcucgac aaacgacuau      720

uuuggauuca guacaaucgg gaaggcucga acucccuaau augcucgugc gauuacgacg      780

gcggaagcgu acacauaagc aagcacccca cgcagcacaa ccucuuugca augucccugu      840

ucggugaccg aaucuucuac uccaccugga aaaugaagac cauauggauc gcgaacaaac      900

auacagggaa agauaugguc agaaucaacc uacacagcuc cuucgucccc cuaggagaac      960

uaaaggucgu acauccacuc gcccaaccca aagcggaaga cgacaccugg gaaccggaac     1020

aaaaauugug caaauuaaga aaggguaauu gcuccagcac ugucugcggg caagaccucc     1080

aaucacaccu cugcaugugc gcggaagggu augcccugag ccgggaccgc aaauauugcg     1140

aagacgucaa ugaaugcgcc uucuggaacc acggauguac gcuugguugc aaaaacacac     1200

ccgggagcua cuacuguacc ugccccguag gcuucguccu acugccggac ggcaagcggu     1260

gucaucagcu agucaguugc ccacgcaacg uuucagaaug cagccacgac ugcguccuaa     1320

cauccgaggg accacucugu uucugcccag aaggcucagu gcuagaaaga gacggaaaaa     1380

caugcagcgg gugcucaagc ccagauaaug gcgggugcuc gcaacuaugu gugccacuau     1440

ccccugucuc cugggaaugc gacugcuucc ccggauacga ucuccaacuc gacgaaaagu     1500

caugcgccgc caguggcccc caacccuuuc uucuauucgc caacagccaa gacauucgcc     1560

acaugcacuu cgacggaaca gacuacggaa cccucuuauc ucaacagaug ggcaugguuu     1620

acgccuuaga ucacgacccu guggaaaaca aaauauacuu cgcccacaca gcacuaaaau     1680

ggaucgaaag agcaaauaug gacggcucac aacgagaacg ccucauagaa gagggcguag     1740

acguacccga aggccuagcg guugacugga uaggcagaag guucuacugg acugaccgag     1800

gcaagucucu gauagggcgc ucggaccuga acggcaaacg cuccaaaauc auaacaaagg     1860

agaacaucuc ccaacccaga ggaaucgcag uucacccaau ggccaaacga cuguucugga     1920

ccgacacugg aaucaacccg cggaucgaau cuuccagucu acaggggcug gggcgucucg     1980

uuauugcauc gagcgaccug auauggccca gcggcauaac gauagacuuc cugacagaca     2040

aacuguacug gugcgacgca aaacaaagcg ugaucgaaau ggccaaucuc gacggaucaa     2100

aaagacgcag acucacacag aacgacgugg gccacccuuu cgcuguagcc guauucgaag     2160

acuacgucug guucucagac ugggccaugc ccagcguaau gcgaguuaac aaacgcaccg     2220

guaaagacag aguccgucuc caaggcucaa ugcuaaagcc uaguucccuu guaguaguac     2280

auccacuagc uaaacccggu gcagacccgu gccuauacca gaacggugga ugugaacaca     2340

uuugcaaaaa gcgauuggga accgccuggu gcagcuguag agaaggauuc augaaagcga     2400

gugacggaaa aacaugccuc gcacucgacg gccaccagcu ccuagccgga ggggaaguag     2460

aucucaaaaa ccaagugacg cccuuagaca uacuaagcaa aaccagagua ucggaggaca     2520

acaucacgga gagccaacac augcuuguag cugaaaucau gguaagcgac caagacgauu     2580

gcgcgccagu cggaugcagc auguacgcac ggugcaucuc cgaaggugaa gaugcuaccu     2640

gccagugccu aaaaggauuu gcgggagacg gcaaacuaug uagcgauauc gacgaaugcg     2700

aaaugggagu cccugucugu ccgccagcaa gcuccaaaug caucaacacc gagggagguu     2760

acguaugccg augcuccgag ggauaucaag gagacggcau acacugccuc gacauagacg     2820

aaugccaacu gggagagcac uccugcggcg aaaacgcaag cuguaccaac acagagggcg     2880

gcuacacaug caugugcgcc ggccgccuau cugaacccgg acucaucugc cccgacucga     2940

ccccuccucc gcaccuacgu gaggacgacc accauuacag cgugcgaaau uccgacucgg     3000

agugcccccu aucccacgac ggauacugcc uucaugacgg cgucugcaug uauaucgaag     3060

cccuagacaa auacgcgugu aauugcguug ucggcuacau cggggaacga ugccaguacc     3120

gcgaccuaaa auggugggaa cuaaggcacg ccgggcaugg ccagcagcag aaagucauag     3180

ucguggcagu cugcguagug gugcucguca ugcuacuccu acuaucacuc uggggagcgc     3240

acuacuaccg cacccaaaaa cuucuaagca aaaaucccaa aaacccauac gaggaaucaa     3300

gccgggaugu ucgaucgagg cgaccagcgg acacagaaga uggcaugagc ucgugcccgc     3360

agcccugguu cguggugauc aaggagcauc aagaccugaa aaacggggga caaccaguag     3420

ccggugaaga cggccaagca gccgacggua gcaugcagcc aaccucaugg agacaagaac     3480

cacaacucug cgguaugggc acagaacagg gcugcuggau ucccgucuca uccgacaagg     3540

gcagcugccc ccaaguaaug gagcgauccu uccacaugcc aagcuacgga acgcagaccc     3600

uagaaggcgg gguagaaaag ccgcauuccc ugcugucugc caacccccug uggcaacagc     3660

gcgcacucga cccaccucac cagauggaac ucacacaaug aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  4586
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt8)

<400>  4586
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggcc gacgaaugga aaugcucugc gccggccgug      120

uccccgcacu ucuccucugc cucggauucc accuacucca agccguccuc uccaccaccg      180

ucauccccuc augcaucccc ggagaauccu ccgacaacug caccgcccua guacaaacag      240

aagacaaccc ccgcgucgca caaguuucca ucaccaaaug cuccucagac augaauggcu      300

acugccucca cggacaaugc auauaccuag ucgacauguc ccaaaacuac ugccgcugug      360

aagucggaua cacaggcguc cgcugcgaac acuucuuccu caccguccac caaccccuau      420

ccaaagaaua cgucgcccuc accgucaucc ucauaauccu auuccucauc acaguugucg      480

gcuccaccua cuacuucugc cgcugguacc gcaauagaaa auccaaagaa ccaaaaaaag      540

aauacgaacg cguaaccuca ggcgaccccg aacucccaca agucuaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  4587
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt8)

<400>  4587
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagaaggcg aaauaaccac auucaccgcc cucaccgaaa      120

aauucaaccu ccccccaggc aacuacaaaa aaccaaaacu ccuauacugc uccaacggcg      180

gacacuuccu ccgcauccuc cccgacggca cagucgacgg aaccagagac cgcucagacc      240

aacacaucca acuccaacuc uccgccgaau cagucggaga aguauacauc aaaagcaccg      300

aaaccggaca auaccuagcc auggacaccg acggcuuacu cuacggcuca caaaccccca      360

acgaagaaug ccucuuccuc gaacgccucg aagaaaacca cuacaacaca uacaucucca      420

aaaaacacgc agaaaaaaac ugguucgucg gccucaaaaa aaacggcucc ugcaaacgcg      480

gcccccgcac ccacuacggc caaaaagcca uacucuuccu cccccucccc gucucaucag      540

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  4588
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt8)

<400>  4588
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggggguag ggggagggga uguggaggau guaacgccga      120

ggccaggggg augccaaaua aguggaagag gggccagggg auguaacggg aucccgggag      180

cggcagcgug ggaggcagcg cugccgagaa ggagaccgag aaggcacccg agugugaacc      240

cgaggagcag ggcggcaggg agcccgagaa caagagggag aaggacagag gaaagaccau      300

cggggagcag guugggggau cgagggcgag gaagggcgcu gccgggaggg agauugggag      360

ggagagggag ggggagagcg ccagagaggg ugggaggaag ggggagagga agagggacgg      420

cggcaccgag ggcggcgccg gcggcaaggg gaagcagacc agggccggcg ggaacgaugg      480

cggcggggag cauaacgacg cuaccagcau ugcccgaaga cggaggaucg ggcgcauucc      540

cgccagggca uuuuaaagau ccgaagaggc uguacuguaa aaauggaggg uucuuucuga      600

gaauacaucc ggauggacgg guagauggag ugagagagaa gagugacccg cacauaaagu      660

ugcaacugca agcggaagag agaggaguag ugagcauaaa agggguaugu gccaacagau      720

aucuagcaau gaaggaagau ggaaggcuac uggcaagcaa guguguaacg gacgagugcu      780

uuuucuucga aaggcuagag aguaacaacu auaacacgua cagaagcagg aaauauacaa      840

guugguaugu ggcgcuaaag aggacgggac aauacaagcu ggggagcaag acagggccgg      900

ggcaaaaggc aauacuguuu uuaccaauga gugcgaagag uuaaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  4589
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt8)

<400>  4589
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uccuaaccug gauccuaccc acccuucucu      120

accgauccug cuuccacauc aucugccuag uaggaaccau cucacucgca ugcaacgaca      180

ugacacccga acaaauggcc accaacguca acugcuccuc cccagaacgc cacacacgca      240

gcuacgacua cauggaaggc ggagacaucc gcguccgccg ccucuucugc cgaacacaau      300

gguaccuccg caucgacaaa cgcggcaaag uaaaaggcac acaagaaaug aaaaacaacu      360

acaacaucau ggaaauacgc acaguagccg ucggaaucgu agcaaucaaa ggcgucgaau      420

ccgaauucua ccucgccaug aacaaagaag gcaaacuaua cgccaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa cucauccuag aaaaccacua caacacauac gcaucagcca      540

aauggaccca caacggaggc gaaauguucg ucgcccucaa ccaaaaaggc auccccguca      600

gaggcaaaaa aaccaaaaaa gaacaaaaaa cagcacacuu ccuccccaug gccaucaccu      660

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  4590
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt8)

<400>  4590
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuacucc ccuccgucgu ccuuaaacuc uuccucgccg      120

ccguacucuc cgcacucguc acaggcgaau cacucgaacg acuccgccga ggccucgccg      180

caggcaccuc aaaccccgac cccccaaccg uguccacaga ccaacuacua ccacucggcg      240

gaggacgcga ccgcaaaguc cgcgaccucc aagaagcaga ccuagaccuc cuccgaguca      300

cccucuccuc caaaccccaa gcccuagcca cccccaacaa agaagaacac ggcaagcgaa      360

aaaaaaaagg caaaggccua ggcaaaaaac gcgacccaug ccuacgcaaa uacaaagacu      420

ucugcaucca cggcgaaugc aaauacguaa aagaacuccg agccccauca ugcaucugcc      480

accccggcua ccacggagaa cgcugccacg gccuaucccu acccgucgaa aaccgccucu      540

acaccuacga ccacacaaca auccucgccg ucgucgcagu cguccucuca uccguaugcc      600

uccucgucau cgucggccua cucauguucc gcuaccaccg acgaggcggc uacgacgucg      660

aaaacgaaga aaaagucaaa cucggaauga caaacuccca cuaaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  4591
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt8)

<400>  4591
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggucacca agcuacuccc cgcucuccug cuacaacacg      120

uccugcucca ccuccuacuc cuccccauag ccauaccaua cgccgaagga caacgcaagc      180

gccguaauac aauacaugag uucaagaaaa gcgccaaaac cacccuuauc aaaaucgacc      240

ccgcccuaaa aaucaagacc aaaaagguga acaccgccga ccaaugcgcc aacagaugca      300

ccagaaacaa gggccucccc uucacaugca aagccuucgu auucgacaag gcccgcaaac      360

aaugccuaug guucccauuc aacuccaugu ccuccggcgu caagaaagag uucggccacg      420

aauuugaccu cuacgaaaau aaagacuaca uccgaaacug caucaucggc aaaggacgcu      480

cauacaaagg caccguaucc aucaccaaau caggcauaaa augccaaccc uggagcucaa      540

ugauccccca cgaacacuca uuucuaccau ccuccuaccg aggcaaagac cuccaggaaa      600

auuacugcag gaacccgcgc ggggaagaag gcggacccug gugcuuuacc uccaaccccg      660

aaguacggua cgaagucugc gacauacccc aaugcuccga aguagaaugc augacaugca      720

acggagaauc cuaucggggc cucauggauc acacagaauc agguaaaauc ugccagcgcu      780

gggaccacca gaccccucac cgccauaaau uccucccaga acgcuaccca gacaaagggu      840

ucgacgacaa cuacugcaga aacccugacg gccagccacg cccauggugu uacacacuag      900

acccccacac ccgaugggaa uacugcgcca ucaaaacaug ugcagacaau acaaugaaug      960

acaccgacgu cccacucgaa accaccgaau gcauccaagg gcagggagaa ggauaccgag     1020

gcacggucaa caccaucugg aacggcauac ccugccaacg gugggacagc caauauccgc     1080

acgaacacga caugacucca gaaaacuuca aaugcaaaga ccucagagag aacuacugca     1140

gaaaucccga cggauccgaa ucacccuggu gcuucaccac ggaccccaac auccgcguag     1200

gcuacugcuc acaaauacca aacugcgaua ugagccacgg ucaagacugc uaucgcggca     1260

acggcaaaaa cuacauggga aaccucucac agacccgcuc aggccuaacg uguagcaugu     1320

gggacaaaaa cauggaggac cuucaucggc acaucuucug ggaacccgac gcauccaaac     1380

uuaacgagaa cuacugccga aacccagacg acgacgccca cgggccaugg ugcuacacag     1440

gcaacccacu caucccgugg gacuauugcc ccauaagccg cugcgagggc gacacaaccc     1500

caacaaucgu gaaccuggac cacccuguca ucucgugcgc aaaaacaaaa cagcuucggg     1560

ucgucaacgg caucccaaca cgaacaaaca uaggguggau ggucucucua cgcuacagaa     1620

acaaacacau cugcggcggc ucacucauca aagaaagcug gguccucaca gcucgccaau     1680

gcuucccauc aagagaccuc aaagauuacg aagccuggcu aggcauacac gacguacaug     1740

gaaggggaga cgaaaaaugc aaacaaguac uuaacguaag ccaacucguc uauggcccag     1800

aaggaagcga ccucguccuc augaaacuag cacgcccagc cguccucgac gacuuuguaa     1860

gcaccauaga ccuccccaac uauggcugca ccaucccaga gaaaacgagu ugcucagucu     1920

acggcugggg auacacggga cugaucaauu acgacggacu acuccggguc gcacaccucu     1980

acaucauggg caacgaaaaa ugcucccaac accaccgcgg caaaguaacu cucaacgaaa     2040

gcgaaaucug cgccggagcc gagaaaaucg gcucaggccc augcgaaggc gacuacggcg     2100

gaccccuugu uugcgaacaa cacaaaauga ggaugguacu cggcguaaua guucccggca     2160

gggggugcgc caucccaaac cgacccggaa uauuugucag aguagcauac uacgcgaaau     2220

ggauucacaa aaucauacua accuacaaag ucccccaguc guaaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  4592
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt8)

<400>  4592
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaagccg ccgcaaucgg cauagaccuc gguacgacgu      120

acagcugcgu aggcgucuuc caacacggca agguggaaau aaucgcuaac gaccaaggca      180

acagaaccac accgucguac gucgcauuca ccgacaccga acgacucauc ggggacgcgg      240

ccaaaaacca agucgcacua aacccccaaa acacaguguu cgacgccaaa cgacucaucg      300

ggagaaaauu cggcgacccc guaguccagu ccgacaugaa acacuggccc uuccaaguaa      360

ucaacgacgg agauaaaccc aaaguacaag ucagcuacaa aggagagacc aaggccuucu      420

acccagagga aaucucaagc auggugcuga caaaaaugaa agaaaucgca gaagccuacc      480

uaggauaccc agucacgaac gccgucauca ccguccccgc auacuucaac gacagccaaa      540

gacaggccac caaagacgcc ggagucaucg caggacucaa uguccuacga auaauaaacg      600

agccaaccgc agccgccaua gcauacggac ucgaccgaac aggcaaagga gaacgcaacg      660

uccuaaucuu cgaccucggg ggcgggaccu ucgacgucuc cauccuaaca auagaugacg      720

gcaucuucga agugaaagcc accgccggcg acacacaccu cgggggagaa gacuucgaca      780

accgccucgu aaaccacuuc gucgaagaau uuaagcgaaa acacaagaaa gacaucagcc      840

aaaauaagcg cgcggugcga cgccugagaa ccgcaugcga gcgagccaaa cgaacgcucu      900

cauccucaac ccaagcguca cucgaaaucg acucacucuu cgagggaauc gacuucuaca      960

ccucaaucac gcgagcccgc uucgaagaau uaugcucaga ccucuuccga ucaacacuag     1020

aacccgucga aaaagcccuc agagaugcaa aacuggacaa agcacaaauc caugaccuug     1080

uccuaguagg aggcucaacc aggaucccca aaguacaaaa acugcuccaa gacuucuuca     1140

augggcgaga ccucaacaag uccauaaacc ccgacgaagc agucgcauac ggggcagcag     1200

uccaagcagc aauauuaaug ggcgacaagu cggaaaacgu ccaagaccuc cuacuacuag     1260

acgucgcgcc acuaagucua gggcucgaaa ccgcgggagg cgucaugacu gcccuaauca     1320

aacgcaacuc caccaucccc acaaaacaaa cccaaauauu caccacauac uccgacaacc     1380

aaccaggagu acugauacaa guauacgaag gcgaacgagc caugaccaaa gacaacaacc     1440

uacuaggacg cuucgaacuc agcggaaucc cacccgcccc cagaggagua ccccaaauag     1500

aagucacauu cgacaucgac gcaaacggca uccuaaacgu uacagcgacc gacaaaucca     1560

ccggaaaagc aaacaagaua acgaucacaa acgacaaagg cagacucucc aaagaggaga     1620

ucgagagaau gguccaagaa gcagagaaau acaaagcaga agacgaaguc caacgugaac     1680

gcgucagcgc caagaacgca cucgagucgu acgccuucaa caugaaaagc gccgucgagg     1740

acgaaggacu caaggggaaa aucucagaag ccgacaaaaa gaaaguacuc gacaaaugcc     1800

aagaaguaau cagcuggcua gaugccaaca cacucgccga aaaagacgag uucgaacaca     1860

aacgcaaaga auuagaacaa gucuguaacc ccaucaucuc cggacucuac caaggcgcag     1920

gcggaccagg ccccggcggc uuuggcgcac aaggccccaa aggcggcagc gguuccggcc     1980

ccacaauaga agaaguagac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4593
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt8)

<400>  4593
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaaagcgg cagcaaucgg aaucgacuua ggcaccaccu      120

acucgugcgu gggagucuuc caacacggca agguggaaau caucgcaaac gaccagggca      180

accgcaccac ccccagcuac guagccuuca cagacaccga acgccugaua ggagacgcag      240

cgaaaaacca ggucgcacuc aacccacaaa acacagucuu ugacgcaaaa cggcucauag      300

gaagaaaauu cggcgacccg gugguccaga gcgacaugaa acacuggccc uuccagguga      360

uuaacgacgg agacaagccg aaaguccaag ucucguacaa aggcgaaacc aaggcauucu      420

acccggaaga aaucuccucc augguccuaa ccaaaaugaa agaaauagcc gaagcauacc      480

ucggcuaccc cgucaccaac gcgguaauaa ccguccccgc auacuuuaac gacagucaac      540

gucaggccac caaagacgca ggggucauag cagggcucaa cguccuccga aucaucaacg      600

aacccaccgc agcagccaua gcauacgguc ucgaccgcac aggcaaaggc gaacgaaacg      660

uccuaaucuu cgaccuaggu gggggcaccu ucgacgucuc aauccuaaca auagacgacg      720

gcauauucga aguaaaggca accgcaggcg acacccaccu aggcggcgaa gacuucgaua      780

accggcucgu gaaccacuuc gucgaagagu ucaaacgcaa gcacaagaaa gacauaucgc      840

aaaacaaacg agcaguaagg cgacuccgaa ccgcgugcga acgagcaaaa agaacccuaa      900

gcucgagcac gcaggccagc cucgaaauag acucccucuu cgaagggauc gacuucuaca      960

caucaauaac acgagcacga uucgaagaac ucugcagcga ucuauuucgc ucaacccucg     1020

agccggucga aaaagcccuc cgcgacgcga aacuagacaa agcccagaua cacgaccuag     1080

uccuaguagg gggaucaacc aggauaccaa aaguacaaaa acuacuccaa gacuucuuca     1140

acgggcgcga ccugaacaaa ucuaucaacc cagacgaagc cgucgcguac ggcgccgcug     1200

uccaagccgc aauucugaug ggagacaaaa gugaaaacgu acaagaucuc cugcuacuag     1260

acguagcccc acuaucacug ggauuagaaa ccgcgggcgg agucaugacc gcccuaauaa     1320

aaagaaacuc aacaauccca acgaaacaaa cacaaaucuu caccaccuac agcgacaacc     1380

aacccggagu gcucauccaa guguacgaag gcgaacgcgc aaugacaaaa gacaacaacc     1440

uccuaggaag auucgaacua uccggcaucc caccagcccc acgcggaguc ccacagauag     1500

aagucacauu ugacauagac gcgaacggaa uacuaaacgu aacagcgacc gacaaaucga     1560

cgggcaaggc aaauaaaaua accaucacga augacaaagg gcgccuaagc aaggaagaga     1620

ucgaaagaau ggugcaggaa gccgaaaagu acaaggccga ggacgaaguc caaagagaac     1680

gggucagcgc caaaaacgca cuagaaucgu acgccuucaa caugaaaucc gcggucgaag     1740

acgaaggacu caaaggaaaa auaagcgaag cugacaaaaa gaaaguacuc gacaaaugcc     1800

aagaaguaau cuccuggcuc gacgcaaaca cauuagccga gaaggacgag uucgaacaca     1860

aacgaaaaga acuugaacaa guaugcaacc ccauuauuuc aggccuauac caaggagcag     1920

gagggcccgg gcccggaggc uucggcgcgc aaggcccaaa aggaggaucc ggaagcggac     1980

cgacaaucga agaagucgac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4594
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt8)

<400>  4594
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaccgcca agggcaucgc caucgggaua gaccucggaa      120

caaccuacuc augcgucgga gucuuccaac acggcaaagu ggagauaauc gccaacgacc      180

aaggaaaccg aacgacaccc ucauacgugg cguucacaga uacagagcgg uuaaucggcg      240

acgcagccaa aaaccaaguc gccaugaacc cacaaaacac ggucuuugac gccaaaaggc      300

uaauuggcag aaaauucaac gaccccguag uccaggccga caugaaacuc uggcccuucc      360

aagucauaaa cgaaggcggc aaacccaaag uccuagucuc auacaaaggc gaaaacaaag      420

cauucuaccc ggaagaaauc ucgagcaugg ucuuaacaaa auuaaaagaa acggccgaag      480

cauuccuugg acaccccguc acgaacgcag uaaucacagu ccccgcauac uucaacgacu      540

cccaacgcca ggcgacaaaa gacgccgggg ucauagccgg ccuaaacguu cugaggauaa      600

ucaacgagcc gaccgccgca gccauagcgu acggacuuga caaaggagga caaggcgaac      660

gccacguacu caucuucgac cugggcggcg gcaccuuuga cgucuccauc uuaaccaucg      720

acgacggcau cuucgaagua aaagccacgg ccggagacac acaccuuggc ggagaagacu      780

ucgacaaccg gcucgucagu cacuuugucg aagaguucaa gcgcaaacac aagaaagaua      840

ucucgcaaaa caaaagagca guccgaagac uccgcaccgc cugcgaacgc gccaagagaa      900

cacucagcag cucaacacag gcaaaccugg aaaucgacuc acucuacgaa ggcauagacu      960

ucuacaccuc aauaacacga gcgcgcuucg aagaacuaug cgccgaccuc uucagaggga     1020

cccuggaacc ggucgaaaaa gcccuccgag acgccaaaau ggacaaagca aaaauccacg     1080

acauaguccu aguagguggg ucaacccgaa uccccaaagu gcaacgacuc cuccaagacu     1140

acuucaacgg gcgcgaccuc aauaaaucaa ucaaccccga cgaagcagua gcauacggcg     1200

cagcagucca agcagcgauc cuaauggggg acaagagcga aaaaguccag gaucuccucc     1260

uccuugacgu cgcaccucua ucucuaggac uagaaaccgc agggggugua augacagcac     1320

ucaucaaaag aaacucaaca auacccacca aacaaacaca aaucuucaca accuacuccg     1380

acaaccaacc aggaguacua auacaagucu acgaagggga acgcgccaug accaaagaca     1440

acaaccuccu gggccguuuc gaccuaaccg guaucccacc agcaccacgc ggaguaccgc     1500

aaauagaagu gacguucgac auagacgcaa acggaauccu caacgucacc gcgaccgaca     1560

aaucaaccgg caaagugaac aaaaucacca ucacaaacga caaagggcga uuaagcaaag     1620

aagaaaucga acgaaugguc cucgacgcag aaaaauauaa ggccgaagac gaaguccaac     1680

gagagaaaau agccgccaaa aacgcauuag aaucauacgc cuucaauaug aaaagcguag     1740

uaucagacga aggccuaaaa ggcaaaauca gcgagagcga caaaaacaag auacuagaca     1800

aaugcaacga acuccuaagc uggcucgagg uaaaccaacu cgcagaaaag gacgaguucg     1860

accacaaaag aaaagaacua gagcaaaugu guaacccaau cauaacaaaa uuauaccaag     1920

gaggcugcac ggggcccgcc ugcggaacag gcuauguccc aggaagaccc gccaccggcc     1980

ccacgauaga agaagucgac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4595
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt8)

<400>  4595
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgcccggg gacccgcaau cggcaucgac cuaggaacca      120

cauacagcug cguaggcgug uuccaacacg gaaaagucga gauaaucgcc aacgaccaag      180

gaaaccgaac caccccauca uacguagcgu ucaccgacac cgaaagacuc aucggggaug      240

cagcgaagaa ccagguggcu augaacccca caaacacaau cuucgacgcc aaacgccuaa      300

uagggagaaa auucgaagac gcaacagucc aaucagacau gaaacacugg cccuucaggg      360

ucgucucaga aggaggaaaa cccaaaguac aagucgaaua caaaggcgaa acaaaaacgu      420

ucuucccaga agagaucuca uccauggucc ucacaaagau gaaggaaaua gccgaagccu      480

accuaggcgg caaaguccac agcgcaguca uaaccguacc agcauacuuc aacgacagcc      540

aacggcaagc cacaaaagac gcaggaacca ucaccggguu aaacguacua cgaauaauaa      600

acgaacccac agcagcagcc aucgcguacg gccucgacaa gaaaggcugc gccggaggcg      660

agaaaaacgu acucaucuuc gaccucggcg gaggcacauu cgacguaucg auacucacaa      720

uagaagacgg cauauucgaa gucaaaucaa ccgccggaga uacacaccuu ggaggggagg      780

acuucgacaa cagaauggug agccaccuag cagaggaguu caaacgaaaa cacaagaaag      840

acauaggacc caacaaaagg gccguacgca gacucagaac agcaugcgaa agagccaaac      900

gaacacuauc auccuccaca caggccagca uagaaauaga cucacuauac gaaggagucg      960

acuucuacac cagcaucaca cgcgccagau ucgaagaacu caacgccgac cuauuccgag     1020

gcacccucga gccggucgag aaagcgcucc gagacgcaaa acucgacaaa ggacaaauac     1080

aagaaauagu ccucgucgga ggcuccaccc gaaucccuaa aauacaaaaa cuacuccaag     1140

acuucuucaa cggaaaagaa cuaaacaaau caaucaaccc cgaugaagcc guugcauacg     1200

gcgccgcugu ccaagcagca auccuaauag gagauaaaag cgaaaacgua caagaccucc     1260

ugcuacuaga cgucacccca cucucacucg gaaucgagac cgccggcggu guaaugaccc     1320

cacucauaaa acgaaacacc accaucccca ccaaacaaac acagacguuc accaccuacu     1380

ccgacaacca aucauccgug cuagugcaag ucuacgaagg cgaaagagcc augaccaaag     1440

acaacaaucu ccucggcaaa uucgaccuga cgggcauacc cccagcccca cgaggcgucc     1500

cccaaaucga ggucaccuuc gacauagacg cgaacggcau ccucaacguc acugcugcag     1560

acaaaucgac aggaaaggaa aacaaaauca ccaucacaaa cgacaagggg cgccucagca     1620

aagacgacau cgaccgaaug guacaagaag cagaacgcua caagagcgaa gacgaagcca     1680

acagagaccg cgucgccgcc aaaaacgccc ucgaauccua cacauacaac auaaaacaaa     1740

ccgucgaaga cgaaaaacua cgcggaaaaa uaagcgagca agacaaaaac aaaauauuag     1800

acaaaugcca agaaguaauc aacuggcucg accgcaacca aauggccgaa aaagacgaau     1860

acgaacacaa acaaaaagaa cucgaacgag uaugcaaccc gauaaucagu aagcuguauc     1920

aaggaggccc aggaggcgga agcggcggcg gagguucggg cgcguccgga ggcccaacaa     1980

uagaagaagu cgacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  4596
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt8)

<400>  4596
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgugguag gcauagaccu gggcuuccag agcuguuaug      120

ucgcaguagc ccgcgcaggc ggcauagaaa caaucgcaaa cgaguacagc gaccgcugca      180

caccggcaug caucucguuc ggacccaaaa accguagcau cggcgcggca gcgaaaagcc      240

aggucauaag caaugcgaaa aacacagucc agggauucaa acgcuuccac ggccgagcau      300

ucuccgaccc auucgucgaa gcagagaaaa gcaaccuggc auacgacauc guccaguuac      360

cgaccggccu aaccgggauc aaagucaccu acauggaaga ggaacgcaac uucaccacag      420

aacaagucac cgccaugcug cuaagcaaac ugaaagagac ugcagagucc guacucaaga      480

aaccaguggu ggacuguguc guaagcgugc cgugcuucua cacggacgcc gaacgacgua      540

gcgugaugga cgcaacacaa auagcgggac ugaacugucu ccgccuaaug aaugaaacga      600

cagcaguagc ccucgcuuac ggaauauaca aacaagaccu acccgcgcuc gaagagaaac      660

cccgcaacgu cgucuucgug gacaugggac acucggccua ccaagucucc gucugcgccu      720

ucaaccgggg caaacugaaa guccucgcca ccgcauucga caccacacuu ggaggccgaa      780

aauucgacga aguucucguc aaccacuucu gcgaagaguu cgggaagaaa uacaaacuug      840

acauaaaauc caaaauccga gcacugcucc gacucaguca agaaugcgaa aaacuaaaga      900

agcucauguc cgcgaacgcc agcgaccucc cccuauccau cgaaugcuuu augaacgacg      960

ucgacgucuc cggaaccaug aaccgaggga aauuccuaga aaugugcaac gacuuacuag     1020

cgagaguaga accaccccua cgaagcguac uagaacagac caaauuaaag aaagaagaua     1080

ucuacgcagu agaaauagug ggcggagcaa cccgcauacc cgccguaaaa gagaaaaucu     1140

caaaauucuu uggcaaagaa cucucgacaa cacuaaacgc cgacgaagca gugacccgcg     1200

ggugcgccuu gcaaugcgca auucucagcc ccgcuuucaa aguaagagaa uuuucaauaa     1260

cagacgucgu accauacccc auaucacucc gcuggaacuc cccagcagaa gaaggaagcu     1320

ccgacugcga agucuucucc aaaaaccacg cagcccccuu cucuaaaguc cucaccuucu     1380

accggaaaga acccuucacc cuagaagccu acuacucguc accacaggac cuaccauauc     1440

ccgaccccgc aaucgcgcaa uucuccgucc aaaaaguaac accccagagc gacgggagca     1500

gcagcaaagu uaaaguaaaa guacguguaa acguacacgg aaucuucuca gucuccucag     1560

ccucccucgu cgaaguccac aaaagcgaag aaaacgaaga accaauggaa accgaccaga     1620

augcaaaaga agaagagaaa augcaagucg accaagaaga accccacguc gaggagcaac     1680

aacaacaaac uccagccgaa aacaaggccg aaucagaaga aauggagacc ucacaagccg     1740

ggucaaaaga caagaaaaug gaucaaccgc cccaagcgaa gaaagcgaaa gucaaaacau     1800

ccacagucga ccuccccaua gagaaccaac ugcucuggca aaucgaccgc gagaugcuca     1860

accucuacau cgagaacgaa ggaaaaauga ucaugcagga caaacuagaa aaagaaagga     1920

acgacgccaa aaacgccgug gaagaguacg ucuaugaaau gcgcgacaaa uuaagcggag     1980

aguacgagaa auuugucucc gaagacgaca gaaacuccuu cacacuuaaa cucgaagaca     2040

ccgaaaacug gcuauacgaa gacggcgagg accagcccaa acaaguauac guggacaaac     2100

ucgcagagcu gaaaaaccua ggacaaccca ucaaaauccg auuucaagaa agcgaagaac     2160

gccccaagcu guucgaggaa cucggaaaac aaauccaaca auacaugaaa aucauaucau     2220

ccuucaaaaa caaagaggac caauacgacc accucgacgc cgcagauaug acgaaaguag     2280

aaaaguccac caacgaagcg auggaaugga ugaacaacaa acucaaccua caaaacaaac     2340

aaucgcucac aauggauccc gugguaaaga gcaaggagau cgaggcaaaa auuaaagaac     2400

ucacauccac augcagcccc auaaucucaa aacccaaacc aaaggucgaa ccgccaaaag     2460

aagaacagaa gaacgccgag caaaacggcc caguagacgg ccaaggcgac aacccaggcc     2520

cccaagcagc ggaacaggga accgacacgg ccguccccuc agauucggac aagaaacucc     2580

cagaaaugga caucgacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  4597
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt8)

<400>  4597
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaguggucg gcaucgaccu aggcuuccuc aacugcuaca      120

ucgccgucgc ccgcuccggc gggauugaaa caaucgcaaa cgaguacucg gacaggugca      180

cacccgcuug cauaucacug ggaucgcgga cgcgcgccau aggaaacgca gccaaaagcc      240

agaucguaac aaacgugcgc aacaccaucc auggcuuuaa aaagcuccac ggcaggagcu      300

ucgacgaccc caucguucaa accgagcgca ucagacuacc auacgaauua cagaaaaugc      360

ccaacggcag cgccggggua aaaguccgcu accucgaaga agaacgaccu uucgcgaucg      420

aacaaguuac cggaauguua cuagcaaaac ugaaggaaac cucagagaac gcccucaaga      480

aacccguggc agacugcgua auaucaaucc cuagcuucuu cacagacgca gaaagacguu      540

caguaauggc ggcagcccaa guagcagggc ucaacugccu ccgacuaaug aacgaaacaa      600

cagccguggc ccucgccuac ggcauauaca aacaagaccu gccgccacua gacgaaaagc      660

cccgcaacgu cguguucaua gacaugggac acagcgccua ccaaguccuc gucugcgccu      720

uuaacaaggg caaacucaaa guccucgcca cgacauucga ccccuaccug ggcggacgca      780

auuucgacga agcucucgua gacuacuucu gcgacgaguu caaaacaaaa uacaaaauca      840

acgucaagga aaacucaaga gcccugcucc gacuauauca agaaugcgag aaacuaaaga      900

aacucauguc cgcgaacgcc agcgaccucc cacuaaacau cgaauguuuu augaacgacc      960

uggacgucag cuccaaaaug aaccgcgccc aguucgaaca acucugcgcc agccuacuag     1020

cacgcgugga gccaccccuc aaagccguaa uggaacaagc gaaccuccag cgcgaggaca     1080

uaucaagcau cgagauagua ggcggcgcga cgcgcauccc cgccguaaaa gagcaaauca     1140

caaaauucuu ccucaaagac auuucaacaa cacuuaaugc agacgaagca guagccaggg     1200

gaugcgcucu acaaugcgcc auccucagcc cggcauucaa aguacgcgag uucuccauca     1260

cagaccuagu ccccuacuca aucacacuca gauggaaaac cucauucgaa gacgggagcg     1320

gagaaugcga aguauucugc aaaaaccacc cugccccauu cagcaaagug auaacguucc     1380

acaagaaaga acccuucgaa cuugaagcgu ucuacacaaa ccuucacgaa guccccuacc     1440

cugaugcgcg aaucgguuca uucacaauac agaacguauu cccccaaagc gacggcgacu     1500

cgagcaaagu aaaagucaaa guccgcguaa acauccacgg caucuucuca guagcaagug     1560

ccagcgugau cgaaaaacaa aaccucgaag gcgaccacag cgacgccccc auggagacag     1620

aaacaucguu caaaaacgaa aacaaagaca acauggacaa aaugcaggua gaccaagaag     1680

aaggccacca gaagugccac gccgaacaca cacccgaaga agaaaucgac cacaccggcg     1740

ccaaaacaaa aucggcaguc uccgacaaac aagaccggcu aaaccaaacc cucaagaaag     1800

gcaaaguaaa aucaaucgac cuacccauac aguccucacu cugccgccaa cugggccaag     1860

aucuccuaaa cucauacauc gaaaacgaag gaaaaaugau aaugcaagac aaacucgaaa     1920

aagaacggaa cgacgccaaa aacgcgguag aggaguacgu cuacgacuuu cgggaccgac     1980

ugggcacggu uuacgaaaaa uucaucacac ccgaagaccu aagcaagcua ucugcggucc     2040

uggaagauac cgagaacugg cucuacgaag acggcgaaga ccaaccaaaa caaguguacg     2100

uagacaagcu gcaggaacug aagaaauaug ggcaaccaau ccaaaugaaa uacauggaac     2160

acgaagaaag gcccaaagca cugaacgacc uaggcaagaa aauucaauua gucaugaaag     2220

ugaucgaagc guacagaaac aaagacgaaa gauacgacca ccucgacccu acagagaugg     2280

agaaaguaga gaagugcaua ucagacgcca uguccuggcu aaacagcaag augaacgccc     2340

aaaacaaacu cagccuuacg caagaccccg uggucaaagu cucagaaaua guugcgaaau     2400

caaaggagcu agauaacuuc ugcaacccca uaauauacaa accgaagccc aaagccgaag     2460

uccccgaaga caagcccaaa gccaacagug aacauaacgg gccgauggac ggacagucag     2520

gcacugagac caaaagcgac ucgacaaaag acagcaguca acacacaaag ucguccggag     2580

agauggaagu cgacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  4598
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt8)

<400>  4598
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacucagcc uagucgcagc caugcugcug cuccucagcg      120

cagcacgggc agaagaggaa gacaagaaag aagacguggg aacaguagua ggcauagacc      180

ucggaacgac auacagcugc guagggguau ucaaaaacgg acgagucgag aucauagcca      240

acgaccaggg caacagaaua accccaaguu acguagcguu cacacccgag ggugaacgac      300

ugaucggaga cgcagcgaaa aaccaacuca caagcaaccc cgaaaacaca guauucgacg      360

caaagcgacu aauaggccgc accuggaacg accccucggu ccagcaagac aucaaauucc      420

ugccauucaa agucgucgag aagaaaacaa aacccuacau acaaguagac auagggggcg      480

ggcagacgaa aacguucgcg ccagaagaaa uaagcgcaau gguacugacg aaaaugaaag      540

agaccgcaga agcguaccug ggcaagaaag ucacccacgc agucguaaca gugccagccu      600

acuucaauga cgcgcaacga caagcaacaa aggacgcagg aacaaucgcg ggacugaacg      660

ugaugcgaau cauaaaugaa cccaccgccg ccgcaauagc guacggacua gacaaacggg      720

aaggcgagaa aaacauccua gucuucgacc ugggcggagg uaccuucgac guaagucucc      780

ugacaaucga caacggcgua uucgaagucg uagcaacaaa cggggacaca caccugggag      840

gagaagacuu cgaccagcga guaauggagc acuucauaaa acuauacaag aagaaaaccg      900

gaaaagacgu aaggaaagac aacagagccg uacaaaaacu caggcgggag gucgaaaaag      960

ccaaacgcgc ccuauccagc caacaccaag cgcgcaucga aauagaauca uucuacgagg     1020

gggaagacuu cagcgaaacc cuaacacgcg caaaauucga agaacugaac auggaccuau     1080

uccgcagcac gaugaaacca guacaaaaag uccuagagga cagcgaccua aagaaaagcg     1140

acauagacga aauaguauua gugggcggcu cgaccaggau accaaaaaua caacaacugg     1200

uaaaagaguu cuucaacggc aaagaaccau cgcgagggau caacccagac gaagccgucg     1260

cauacggagc cgcaguucaa gcaggaguac ugagcggcga ccaagacaca ggagaccucg     1320

uacuacugga cgugugccca cucacccuag gcauagaaac aguaggcggg guaaugacaa     1380

aacucauacc aagaaacacg gucgugccca ccaagaaaag ccagauauuc agcacggcaa     1440

gcgacaacca acccaccgua acgaucaaag ucuaugaagg agaacgaccc cucacaaaag     1500

auaaccaccu acugggcacc uucgaucuaa caggcauacc accagcccca agagggguac     1560

cacaaauaga agugacauuu gaaaucgacg uaaacgggau ucuccgagug accgcggaag     1620

acaaaggaac cggaaacaaa aacaaaauaa cgauaaccaa cgaccaaaac agacucacac     1680

cggaagaaau cgaaagaaug gucaacgacg cagagaaauu ugccgaagag gacaagaaau     1740

ugaaagagcg aauagacacc agaaacgaac ucgaaagcua cgccuacuca cucaaaaacc     1800

agauagguga caaagaaaaa cuaggaggga aacuaagcag ugaagacaaa gaaaccaugg     1860

aaaaagccgu cgaagagaaa aucgaauggc uagaaucaca ccaagacgca gacauagaag     1920

acuucaaagc caaaaagaaa gaacuagaag aaauaguaca accaaucaua uccaaacuau     1980

acggaagcgc agggccccca cccacaggag aagaggacac agcggaaaaa gacgaacuau     2040

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  4599
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt8)

<400>  4599
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcacccc gggagcucgc agucggcauu gaucucggaa      120

caacauacuc cugcguagga guguuccagc aagggcgcgu ggaaauacuc gcaaacgacc      180

aaggcaaccg gaccacccca agcuacgugg ccuucaccga cacagagcgg cugguaggag      240

acgcagcaaa aagccaagcc gcgcugaauc cccacaacac agucuucgac gcaaaaaggc      300

uaauuggaag aaaauucgca gacacaacag uacaaagcga caugaaacau uggcccuucc      360

gagucgucuc agaagggggc aaacccaagg ucagagucug cuacagaggu gaagacaaaa      420

cauucuaccc cgaagagaua ucaagcaugg ugcucagcaa aaugaaagag acggccgagg      480

cauaccucgg gcaaccgguc aaacacgcgg uaauaacagu cccagcauac uucaacgaua      540

gccaacgcca agccacaaaa gacgccggag caaucgccgg gcucaacguc cuacgaauaa      600

ucaacgaacc aacagcggca gcaaucgcuu acgggcuaga cagaagaggc gcaggcgaac      660

ggaacguccu gauauucgac cuaggaggag gaacauucga cguaucagug cuaagcaucg      720

acgcaggagu auucgaaguc aaagccacgg caggagacac acaccugggc ggggaagacu      780

ucgacaacag gcuaguaaac cacuucaugg aagaguuccg gcgcaaacac gggaaagacc      840

uaucagggaa caaaagagcc cugcgaaggc ugagaacagc cugcgaacgc gcaaaaagga      900

cacuaagcag cuccacacaa gcaacacuag aaauagacuc ccucuucgaa ggagucgacu      960

ucuauaccuc gaucacgcgc gcacgauucg aagaacuaug cagcgaccuc uuccgaucga     1020

cccuggaacc gguagaaaaa gcccuaagag acgcgaagcu agacaaggcc caaauacacg     1080

acguaguccu cguaggagga ucgacacgca ucccaaaagu acaaaaacuc cuacaagacu     1140

ucuucaacgg gaaagaacuc aacaagucaa uaaaccccga cgaagcagug gccuacggug     1200

ccgcaguuca ggccgcaguc cugaugggcg acaagugcga aaagguucaa gaccuacuac     1260

uccuagacgu ggcaccccuc ucccucggac uagagacagc gggcggaguc augacuacac     1320

uaauccaaag aaacgcaacc aucccaacaa agcaaacaca aacauucaca accuacucag     1380

acaaccaacc aggcguauuc auccaagucu acgagggcga acgcgcaaug accaaagaua     1440

acaaccuacu gggccgauuc gagcucucag gcauaccccc agcaccccga ggagucccac     1500

aaauagaagu uacauucgac aucgacgcca acgggauauu gagcgugacc gcaacagacc     1560

gcucaaccgg aaaggcaaac aaaauaacaa uaacaaacga uaaaggacga cuaagcaaag     1620

aagaagugga gcgcauggua cacgaggcgg aacaauacaa ggccgaggac gaagcccaac     1680

gggacagagu agccgccaaa aacagccugg aagcgcacgu cuuccacguc aaaggaucac     1740

uacaggaaga aucccuccga gacaaaauac ccgaggaaga cagacgaaaa augcaagaca     1800

agugccgaga aguccuagcc uggcucgaac acaaccaacu ggccgaaaaa gaagaauacg     1860

aacaccaaaa gcgagaacua gagcaaauau gcagaccaau auucucgaga cuauacggcg     1920

ggccgggcgu accuggcgga ucgagcugcg gcacccaagc ccgacaaggc gacccaucaa     1980

ccgggccuau aaucgaggaa guggacuaag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  4600
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt8)

<400>  4600
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcaccac gcgaacucgc agucggaauc gaccuaggca      120

ccacauacuc augcgucggc guauuccaac aaggaagagu cgaaauccuc gccaacgacc      180

aaggaaaccg aaccacgcca agcuacgucg cauucacaga cacagaacgc cuggucggcg      240

acgcagccaa aagccaagcc gcacucaacc cacacaacac aguauucgac gcaaaacggc      300

ucauaggccg caaauucgcc gacaccaccg uccaaagcga caugaaacau uggccauucc      360

aagucguaag cgaaggcggc aaacccaaag uccgagucug cuacagaggc gaggacaaaa      420

cauucuaccc agaagaaauc uccagcaugg uacuaaguaa aaugaaagaa accgcagaag      480

cauaccuagg ccaacccgua aaacacgcag uaauaaccgu accaaccuac uucucaaaca      540

gccaacgcca agcaacaaaa gacgcaggag ccaucgccgg ccucaaaguc cucccaauaa      600

uaaacgaagc aaccgcagcc gcaaucgccu acggacucga ccgacgaggc gccggcaaac      660

gaaacguacu cauauucgac cucggcggcg gcaccuucga cguaagcgua cuaagcaucg      720

acgcaggagu cuucgaaguc aaagcaacgg ccggcgacac acaccuugga ggagaagacu      780

ucgacaacag guuagucaac cacuucaugg aagaguuccg ccgcaaacac ggaaaagacc      840

ucucaggaaa caaacgcgca cugcgacggc uacgaacagc gugcgaacgc gcaaaacgca      900

cccccuccag cagcacacaa gccacucucg aaaucgacuc acuguucgaa ggcgucgacu      960

ucuacaaauc cauaacacgc gcacgcuucg aagaacucug cagcgaccuc uuccgcagca     1020

cccucgaacc cguugaaaaa gcccuacgcg acgccaaacu agacaaagcc caaauccacg     1080

acuucguccu gggcggcggc cuccacucac acccccaagg agccgaagua gcagcaggac     1140

uccugcaacg ccaaggagca gaacaagaac accaacccua gggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  4601
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt8)

<400>  4601
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaaaggac cagcaguagg gauagaccuc ggaaccacau      120

acuccugcgu agggguauuc cagcacggca aaguagaaau aauagcgaac gaccaaggca      180

accggaccac cccuuccuac guagccuuca ccgacacaga gcgccucauc ggagacgcgg      240

ccaaaaacca agucgcaaug aaccccacca acacaguauu cgacgcaaaa agacucauag      300

gcaggcgguu cgacgacgca gucguacaaa gcgacaugaa gcacuggccc uucauggucg      360

uaaacgacgc aggacgccca aaaguccaag uagaauacaa gggcgagaca aaauccuucu      420

acccagaaga ggucuccagc augguacuga ccaaaaugaa agagauagca gaagccuacc      480

ucggaaaaac uguaaccaac gcaguaguca cagucccagc cuacuucaau gacagccaac      540

gccaggccac caaagacgcc ggaaccaucg ccggacuuaa cguacuacgc aucaucaaug      600

agccaacggc ggccgcaauc gcguacgggc ucgacaaaaa gguaggagcc gaaagaaacg      660

uccugaucuu cgaccuagga ggaggaacau ucgacgucuc aauccucaca auagaagacg      720

gcauauucga aguaaagagc acggccggcg acacacaccu gggaggagaa gacuuugaca      780

acagaauggu aaaccacuuc auagcagagu ucaagcgcaa gcacaagaag gacaucagcg      840

aaaacaaaag agcaguacgc cgccuccgca ccgccuguga aagagcaaaa cgcacccuca      900

gcuccagcac ccaagcaagu auagaaauug acucacuaua cgaaggcauc gacuucuaca      960

ccagcaucac ccgagcaaga uucgaagaau uaaacgcaga ccucuucaga ggaacccugg     1020

acccagucga gaaagcacua cgagacgcaa aacuagacaa aagucaaaua cacgacauag     1080

uccuagucgg aggcagcaca cgaaucccga agauacagaa acuccuccaa gacuucuuca     1140

acggaaaaga acuaaacaaa agcauaaauc cagacgaagc agucgcauac ggcgcagcgg     1200

uccaagcggc cauacuuuca ggcgacaaaa gcgagaacgu acaagaccug cugcuccugg     1260

acgucacgcc gcucucacua ggcaucgaaa cagccggcgg cguaaugacc gugcucauaa     1320

aacgcaacac aaccauacca acaaaacaga cccagaccuu cacgacauac uccgacaacc     1380

agccaggcgu acucauacag gucuacgaag gagaacgcgc aaugacaaaa gacaacaacc     1440

uccuaggcaa auucgaacuc acagggauac ccccagcacc gcgcggaguc ccacaaauag     1500

aagucaccuu cgacaucgac gcaaacggaa uccuaaacgu auccgccgua gacaaaucaa     1560

ccggaaaaga aaacaaaaua acgaucacaa acgacaaagg ccgccuaagc aaggaggaca     1620

ucgagagaau gguccaggag gccgaaaaau acaaagccga agacgaaaaa caacgcgaca     1680

aaguaaguag caagaacagc cuggaaagcu acgcauucaa caugaaggcg acggucgaag     1740

acgaaaaacu gcagggaaaa auaaacgacg aagacaaaca gaaaauccua gacaaaugca     1800

acgaaaucau aaacuggcug gacaaaaauc aaaccgccga aaaagaagaa uuugaacacc     1860

aacaaaagga gcucgaaaaa gugugcaauc ccauaaucac caaacuauac caaucagcgg     1920

gaggaaugcc cggagggaug ccgggcgggu ucccaggagg gggagcaccc ccaagcggag     1980

gcgcaagcuc gggccccacg auagaggagg ucgacuaagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  4602
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt8)

<400>  4602
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaucagcca gccgcgcggc cgccgcaaga cuggugggag      120

cagccgcgag ccgcggacca acagcagcgc ggcaccaaga cagcuggaac ggacugucac      180

acgaagcauu ccgacucgug aguagaagag acuacgcgag cgaagccaua aaaggggccg      240

uagucggaau cgaccucgga acaacaaaua guugcguagc cgugauggag ggaaaacaag      300

ccaaaguacu agagaacgcg gagggagcga gaaccacacc aagcgucgua gccuucaccg      360

cagauggaga aaggcucgua ggcaugcccg caaaaagaca agcagugacg aacccaaaca      420

acaccuucua cgcgacaaag cgccucaucg gccgacgcua cgacgacccc gaggugcaaa      480

aagacaucaa aaacguacca uucaaaauag ugagagcaag caacggcgac gccugggucg      540

aagcccacgg caaacuauau agccccagcc agauaggggc cuucgucuug augaaaauga      600

aagagaccgc agaaaacuac cuaggacaca cagccaagaa cgcaguaaua accguaccug      660

cauacuucaa cgacagccag agacaagcca caaaggacgc cggccagaua agcggacuua      720

auguacuacg cguaauaaac gaaccgacag ccgccgcgcu cgcauacggc cuagacaaaa      780

gcgaggacaa aguaauagca guauacgacc uaggaggggg aacuuucgac aucucgauac      840

uagaaauaca aaagggaguu uucgagguca agucaacaaa cggggacacc uucuuaggcg      900

gagaagacuu cgaccaagcg cugcuacgcc acaucgugaa agaguucaaa agagaaacag      960

gggucgaccu cacgaaagac aacauggcac uccaaagagu cagagaagcg gcagaaaaag     1020

cgaaaugcga acuaagcagc agcguccaaa cagacauaaa ccuacccuac cuaacaaugg     1080

auagcucagg cccaaaacac cugaacauga agcucacgcg cgcgcaauuc gaggggauag     1140

ugacugaccu caucagaaga accauagcac caugccaaaa agcaaugcaa gaugccgaag     1200

uaagcaaaag cgacauaggg gaagucaucc uagucggagg aaugacgagg augccaaaag     1260

uacaacaaac aguacaagac cucuucggga gagccccguc caaggccgua aacccggacg     1320

aggcaguagc cauaggagcg gccauacaag gaggaguccu agccggggac guaacagacg     1380

ugcugcugcu cgacguaaca ccccugucuc ugggcauuga aacccuagga ggcguuuuca     1440

caaaacucau caacagaaac acgacgauac cgacuaagaa aucccaaguc uucuccacag     1500

ccgccgacgg ucaaacccaa guagaaauca aagucugcca aggagagagg gaaauggccg     1560

gggacaacaa auuacucggg caauucaccc ucaucggaau cccacccgcg ccccgaggcg     1620

ugccccagau agaggucaca uucgacaucg acgccaacgg aauaguacac guaagcgcca     1680

aagacaaagg aacaggccgg gaacaacaga uagucauaca gucaagcgga ggccucagca     1740

aggacgacau cgaaaacaug gucaaaaacg cagagaagua cgcagaagag gaccggagaa     1800

agaaagaacg cguggaagca guaaacaugg ccgaagggau aauacacgac accgagacaa     1860

aaauggagga guucaaagac cagcugcccg cggaugaaug uaauaaacua aaagaagaaa     1920

uaagcaaaau gagggaacua cucgcacgaa aggacucuga aacgggcgag aacauuagac     1980

aagcggcaag cagccuccaa caagcauccc ugaagcucuu ugaaauggca uacaagaaaa     2040

uggcgucgga aagggaaggg uccgggagcu caggcacggg agagcaaaag gaagaccaaa     2100

aggaggaaaa acaauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  4603
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt8)

<400>  4603
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcggacaaag aagccggagg aagcgacggc ccccgcgaaa      120

ccgccccaac auccgccuac agcucgcccg cccgcagccu aggagacacc ggaaucacac      180

cccucucucc cucccacauu gucaacgaca ccgacuccaa cguaucugaa caacaaucau      240

uccucguagu agucgcagua gacuucggca ccaccucguc cggauacgca uacucguuca      300

ccaaagaacc cgaauguauc cacguaauga gacgcuggga aggcggcgac cccggggucu      360

ccaaccagaa aaccccaacc accauacuac ucaccccaga aagaaaauuc cacuccuucg      420

gauacgccgc ccgcgacuuc uaccacgacc ucgaccccaa cgaagccaag caauggcucu      480

acuuggaaaa auucaaaaug aaacuccaua caaccggaga ccucaccaug gacaccgacc      540

ucacagcugc aaacggcaag aaagucaaag cacucgagau cuuugccuac gcgcugcaau      600

acuucaaaga acaagcccuc aaagaacucu ccgaccaagc agggucagag uucgaaaaua      660

gcgacguccg augggucauc accgucccag caauuuggaa acaacccgca aaacaauuca      720

ugcgccaagc cgccuaccaa gcuggccuag cuucaccaga aaacucagaa caacuaauca      780

uagcacucga accggaagca gcaagcaucu acugcagaaa acuacgccuc caccaaauga      840

ucgaacucag cucaaaagcc gccgugaacg gcuacuccgg auccgacacc guaggcgcgg      900

gcuucacaca agccaaagaa cacauccguc ggaaccgcca aucacgaaca uuccuagucg      960

aaaacgucau aggcgaaauc uggagcgaac uagaagaagg cgacaaauac gucguagucg     1020

acucaggcgg aggcacagug gaccucaccg uacaucaaau ccgccuacca gaaggccacc     1080

ucaaagaacu cuacaaagcu acaggcggac cauacggauc acugggcguc gacuacgagu     1140

ucgaaaaacu acuauacaag aucuucggcg aagacuuuau cgaacaauuc aaaaucaaaa     1200

gacccgccgc cuggguagac cucaugaucg ccuucgaauc cagaaagagg gcagccgcgc     1260

ccgaccgcac uaacccccug aacauaacac ucccauucag cuucaucgac uauuacaaga     1320

aauuccgcgg ccacucaguu gaacacgccc uccgcaaauc caacguagac uuuguaaaau     1380

ggucauccca aggcaugcuc cggauguccc ccgacgccau gaacgcccua uucaaaccaa     1440

ccauagauuc cauaaucgaa caccucagag accucuucca aaaacccgaa gucucaaccg     1500

uaaaauuccu uuuccuaguc gggggauucg ccgaagcgcc cuuacuacaa caagcggugc     1560

aagcugcauu cggcgaucaa ugccgaauaa uaauccccca agacguaggc cuaaccauac     1620

ugaaaggggc aguacucuuc ggccucgacc ccgcaguaau caaaguccga cgcuccccac     1680

uaaccuacgg cguaggcgua cucaacagau acguagaagg aaaacaucca ccagagaaac     1740

uccugguuaa agacggaacc agauggugca ccgacguauu cgacaaauuc aucagcgccg     1800

accaaucagu ugcacucggc gaauuaguua agcgaagcua cacccccgcg aaaccauccc     1860

aacucgucau cgucauaaau aucuacagcu cagaacacga caacgucucg uucaucaccg     1920

accccggggu caaaaagugc ggcacgcuca gacucgaccu caccggcacc agcgggacgg     1980

caguaccagc gcgacgcgag auacaaaccc ucaugcaauu cggcgacaca gagaucaaag     2040

ccaccgcgau ugacauagca acaucaaaau cugucaaagu cggaaucgac uucuuaaacu     2100

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  4604
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt8)

<400>  4604
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cucgccgucc ccgagauggg cuugcagggc cuauacauag      120

gcagcucacc cgaaagaagc ccagucccau ccccaccugg aucccccaga acccaagaau      180

ccugcggaau cgcuccccuc accccaucac aauccccaaa accggaaguc cgcgcacccc      240

aacaggccuc auucucaguu guugucgcca uagacuucgg cacaaccuca agcggauacg      300

ccuucagcuu cgccucagac cccgaagcca uacauaugau gcgcaaaugg gaggguggcg      360

accccggcgu cgcccaccag aaaacgccca cuugccuacu ccucacccca gaaggcgccu      420

uccacuccuu cggcuacacg gccagagacu acuaccacga ccucgacccc gaagaagcaa      480

gggacugguu guacuucgaa aaauuuaaaa ugaaaauuca uagcgccaca gaccuaaccc      540

uaaaaacgca auuagaagcu guaaacggca aaaccaugcc cgcccucgaa gucuucgccc      600

acgcacuccg cuucuuccga gaacacgcac uccaagaacu aagagagcaa ucacccagcc      660

uccccgagaa agacacagua cgcuggguac ugaccguacc cgccauaugg aagcaaccag      720

cgaaacaauu caugagagag gccgcauacc ucgcagggcu aguaucccgg gaaaacgcag      780

aacaacuccu cauagcauua gaaccagaag cagccucagu cuauugcaga aaacuccgcc      840

ugcaccaauu gcucgaccuc agcggccgcg ccccaggagg cggucgacuc ggcgaacgac      900

gaagcauaga cucaucauuc cgccaagcca gagaacagcu ccgccgaucc agacacucac      960

gaaccuuccu uguagaaucc ggcgucggag agcuuugggc cgaaaugcaa gccggggacc     1020

gauacgucgu agccgacugc ggcggcggaa ccgucgaccu aacaguacac caacuagaac     1080

aaccacaugg uacccucaaa gaacucuaca aagccuccgg cggucccuac ggagccguug     1140

gcguagaccu cgcauucgaa caacuacucu gcagaauauu cggagaagac uuuauagcua     1200

ccuuuaaaag acaacgaccc gcagccuggg ucgaccuaac uauagccuuc gaagcacgca     1260

aacgaacagc cggcccacac agagccggcg cacucaacau aagccuacca uucucguuca     1320

uagacuucua ccgcaagcaa agaggccaca acgucgaaac cgcccucaga cgaucauccg     1380

uaaacuucgu aaaaugguca agucaaggaa ugcugcgaau gucaugcgaa gcaaugaacg     1440

agcuauucca accgacagua agcggaauca uccaacacau cgaagcgcuc cuagcgcgcc     1500

cugaagucca aggcguaaaa cuucuauucu uaguuggagg auucgcagaa agcgccguac     1560

uucaacaugc aguccaagca gcacucggcg cacgcgggcu ccgagucguc gucccccacg     1620

acguuggccu aaccauacuc aaaggagccg uccucuucgg acaagcccca ggggucgucc     1680

gagugcgcag aucaccgcua acauacggcg uaggcgugcu caaucgcuuc guaccaggca     1740

gacacccgcc cgaaaaacuc cuaguccgag acggacggcg cuggugcacc gacgucuucg     1800

aaagauucgu cgcggcugaa caauccguag cccucggcga agagguacgu cgcagcuacu     1860

gcccagcccg acccggacag agacgaguuc ucaucaaccu cuacugcugu gcagcagaag     1920

acgcccgguu cauaacagac cccggcguaa gaaaaugcgg agcacucucc cuugaacuag     1980

aaccggcaga cugcggacaa gacaccgccg gcgccccacc cggaagacgc gaaaucagag     2040

ccgcaaugca auucggagac acagaaauca aagucacagc aguagacgua agcaccaaca     2100

gaagcgucag agcaagcaua gacuuccucu caaacuaggg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  4605
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt8)

<400>  4605
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgcgaaa ugaccauacu aggcuccgcc guauuaaccc      120

uccuccuugc aggcuaccua gcacaacaau accucccacu accaacccca aaagucauug      180

gcauugaccu cggaaccacg uacugcagcg ucggcgucuu cuucccugga accggcaaag      240

ucaaaguaau acccgacgaa aacggccaca ucuccauacc auccaugguu uccuucaccg      300

acaacgacgu guacgucgga uacgaauccg ucgaacucgc cgacagcaac ccacagaaca      360

ccaucuauga cgcaaaacga uucaucggaa aaauauucac agccgaagaa cucgaagccg      420

aaaucggacg cuauccauuc aaaguacuaa acaaaaacgg caugguagag uucuccguca      480

caagcaacga aaccaucacc gucagccccg aguacguagg aucuagacug cuucuaaaac      540

uaaaagaaau ggccgaagcc uaucugggca ugcccgucgc caacgcagua aucucggucc      600

ccgcagaguu cgaccuaaaa caacgaaacu caaccauaga agcggccaac cuagccggcc      660

ucaaaauacu aagagucaua aacgaaccca cugccgcggc uauggccuac ggucuccaca      720

aagccgacgu cuuccacguc cucgucaucg accucggcgg cggaaccuua gacgucagcc      780

uacucaacaa acaaggcggc auguuccuca cccgcgcaau gagcggcaac aacaaacucg      840

gaggccaaga cuucaaccaa cgccuacucc aauaccucua caaacagauc uaccaaaccu      900

acggcuuugu accaucccgc aaagaagaaa uacaccgacu ccgacaagcc gucgaaaugg      960

ucaaacucaa ccugacccua caccaaagcg cccagcuauc uguacuacua accgucgaag     1020

aacaagaccg caaagaaccc cacucaagcg acaccgaacu ccccaaggac aaacucagcu     1080

cugcggacga ccaccgcguc aacuccggcu ucggccgagg cuuaucagac aagaaauccg     1140

gagaaagcca aguccucuuc gaaaccgaga uaucccgcaa acuauucgac acacucaacg     1200

aagaccuauu ccagaaaauc uuaguaccca uacaacaagu ccucaaagaa ggccaccugg     1260

agaaaacaga aauagacgaa gucguccuag uaggcggcag cacacgcauc ccccgcauua     1320

gacaagucau ccaagaguuc uucggcaaag accccaacac cuccgucgac cccgaccuag     1380

ccgucgugac cgggguagca auccaagccg gcaucgacgg aggcuccugg ccacuacagg     1440

ucucggcacu ugaaaucccg aacaaacacc uccagaaaac caacuucaau uaaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4606
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt8)

<400>  4606
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagcaaucg gcguccaccu cggaugcaca ucagccugcg      120

ucgccgucua caaagacggg cgcgccggcg ucgucgcaaa cgacgcgggc gaccgcguca      180

caccagccgu cgucgcauac uccgaaaacg aagaaauagu aggccuagcc gccaagcaau      240

cccgcauacg caacaucagc aacacaguca ugaaaguaaa acaaauauua ggccgcuccu      300

ccuccgaccc acaggcccaa aaauacaucg cagaaucaaa augccucgua aucgagaaaa      360

acggcaaacu acgcuacgag aucgacacug gcgaagaaac caaguucgua aacccagaag      420

acgucgcccg ccuaaucuuc ucaaaaauga aagaaacggc ccacucaguc cucggcuccg      480

acgccaacga ugucgucaua accguaccau ucgacuucgg cgaaaaacaa aagaacgcac      540

uaggcgaagc cgcccgcgca gcgggauuca acguccuacg ccucauacac gaaccauccg      600

cggcccucuu agcuuacgga aucggacaag acucccccac cggcaaguca aacauccuag      660

uauucaaacu aggaggaacc ucacuaucac ucucagucau ggagguaaac ucaggcaucu      720

accgcguccu cagcaccaac acagacgaca acaucggagg agcccacuuc accgaaacac      780

ucgcccagua ccucgccucc gaguuccagc gaucguucaa acaugacgua cgaggaaacg      840

cacgcgcaau gaugaagcuc acgaacagcg cagaagucgc aaagcacucc cuaagcacac      900

uaggcagcgc aaacugcuuc cuggacucau uauacgaagg acaggacuuc gacugcaacg      960

uaagccgcgc cagauucgaa cuccucugcu caccccucuu caacaaaugc aucgaagcca     1020

uacgcggacu acuagaccaa aacggguuca ccgccgacga caucaacaaa gucguucucu     1080

gcggcggauc cagccgcauc cccaaacugc aacaacucau caaggaccua uuccccgccg     1140

ucgagcugcu aaacuccaua ccacccgacg aaguuauacc cauuggagca gcaauagagg     1200

ccggcauccu caucggcaaa gagaaccucc ucgucgaaga cucccugaug aucgagugcu     1260

ccgccagaga cauacucguc aaaggcgucg acgaaucagg agcaucacgc uucacagucc     1320

uauuccccuc uggaacaccc cuuccagcac gacgacaaca cacccuacaa gcaccaggca     1380

gcauuuccuc cgucugccua gaacucuacg aauccgaugg caaaaacucg gccaaagaag     1440

aaaccaaguu cgcacaaguc guacuccaag accucgacaa gaaagaaaac ggacuccgcg     1500

acauccuggc cgugcucacc augaagcgag auggaucacu acacgugacc ugcaccgacc     1560

aggaaaccgg caaaugcgaa gccaucagca ucgaaaucgc auccuaagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  4607
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt8)

<400>  4607
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgucgucg gacuggacgu gggaagccaa agcugcuaca      120

uagcagucgc ccgggcaggg ggcaucgaaa caaucgccaa ugaguucagc gacagaugca      180

cuccaagcgu caucuccuuc ggauccaaaa acagaacaau aggagucgcc gccaaaaacc      240

aacagauaac ccacgcaaac aacaccgucu caaacuucaa acgguuccac ggcagagcau      300

ucaacgaccc cuucauacaa aaagaaaaag aaaaccuauc auacgaccuc gucccacuca      360

aaaacggagg agucgguauc aaagucaugu acaugggcga agaacaccuu uucucaguag      420

agcaaauaac agcaaugcua cuaaccaaac ucaaagagac agcagaaaac ucgcugaaga      480

aaccagucac agauugcguc auaagcgucc cgagcuucuu caccgacgcc gaacgacgcu      540

caguacuaga cgcagcccaa aucgucggcc ugaacugucu cagacuaaug aacgauauga      600

cggcagucgc ccuaaacuac ggcauauaca aacaggaccu cccaucacug gaugaaaaac      660

cacguaucgu ggucuucguc gacaugggcc acucagcauu ccaagucucc gcaugcgccu      720

ucaacaaagg caaacucaaa guacuaggca cagccuucga cccauuccuu gggggcaaaa      780

acuucgacga aaaacugguc gagcacuuuu gcgcagaguu caaaaccaaa uacaaacucg      840

acgccaaaag caaaauccga gcacuucuac gauuauacca agaaugcgaa aaacucaaga      900

aacucaugag cagcaacucg acagaccucc ccuugaacau cgaaugcuuc augaaugaca      960

aggacguguc agggaagaug aaccggucac aguucgaaga acugugcgcc gaacuccugc     1020

agaaaaucga agucccacug uacucccuac ucgaacaaac ccaccugaaa gucgaagacg     1080

ucucagcagu agaaaucgug ggaggggcaa cccgaauacc ugccgucaaa gaacguaucg     1140

cgaaauucuu cggaaaagac aucaguacaa cgcucaacgc cgacgaagca gucgccagag     1200

ggugcgcacu ccaaugcgcg auccuauccc ccgcguucaa aguacgcgag uucuccguga     1260

cugacgccgu cccauuccca aucucacuaa ucuggaacca cgacucagaa gacacggaag     1320

gaguccacga agucuucagc cgcaaccacg cugcccccuu cucuaaagua uuaaccuucc     1380

uccgccgagg uccauucgaa cucgaagcgu ucuacucaga cccacaaggg guacccuacc     1440

cggaggcgaa aaucggccgc uuuguaguac aaaacgucuc agcccagaaa gacggcgaaa     1500

aaucccgggu caaagucaaa guccgcguca acacccacgg cauauucacc aucucaacug     1560

ccagcauggu cgagaaagua ccaacagagg agaacgaaau gucaagcgaa gccgacaugg     1620

aaugccuaaa ucaaagaccg ccagaaaacc cugacaccga caaaaacgua caacaagaca     1680

auuccgaagc agggacccag ccacaagucc agacagacgc acaacagacc agccaaucac     1740

ccccaucccc agagcucacg agcgaagaaa acaaaauacc agacgcagac aaggcaaacg     1800

aaaagaaagu cgaccagccg ccagaagcga aaaagccgaa aaucaaagua gucaacgucg     1860

aacuccccau agaagcaaac cucguauggc agcucgggaa agaccuccua aacauguaca     1920

ucgagacaga aggcaaaaug auaaugcaag acaaacuaga aaaagaaaga aacgacgcua     1980

aaaacgcagu agaagaguac gucuacgagu uccgcgacaa acucuguggg cccuacgaaa     2040

aauucaucug cgaacaagac caccaaaacu uccuaagacu ccuaaccgaa acggaagacu     2100

ggcucuacga agaaggcgag gaccaagcaa aacaagccua cgucgauaaa cucgaggagc     2160

uaaugaaaau cggcacgccc gucaaagucc gcuuccaaga agcagaagaa cgaccgaaga     2220

uguucgaaga acugggccag cgcuugcaac acuacgcgaa aauagcggcc gacuuccgca     2280

acaaagacga aaaauauaac cacauagacg aaucagagau gaaaaaggua gagaaaagcg     2340

uaaacgaagu aauggaaugg augaacaacg ucaugaacgc ccaagccaag aaaucacuag     2400

accaagaccc cguugucaga gcccaagaaa uaaaaaccaa aauuaaagaa cucaacaaca     2460

caugcgagcc agucgucacc caaccgaaac caaaaauaga aucuccaaaa cucgaaagaa     2520

ccccaaacgg cccuaacauc gauaagaaag aagaggaucu cgaagacaaa aacaacuucg     2580

gggcagaacc cccgcaccaa aacggcgaau gcuaccccaa cgagaaaaac ucugugaaca     2640

uggaccuaga uuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  4608
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt8)

<400>  4608
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaaag uccgacgaca acgaccgcgc cgacgaguau      120

guugggcgcu cgucgccgua cugcucgccg accuacuggc ccuaagugac acccucgcag      180

ugaugagugu agaccuaggc uccgaaucca ugaaggucgc gauagucaaa ccaggagugc      240

cgauggaaau aguccucaac aaggaaucca ggcgaaaaac cccaguaaua guaacccuca      300

aagaaaacga gcgguucuuu ggagacucag cagcaagcau ggcaaucaag aauccaaaag      360

ccacccuacg auacuuccaa caccuacuag gaaagcaggc agacaaccca cacgucgcac      420

uauaccaggc cagguucccg gaacacgagc ugaccuucga cccccaaagg caaacgguac      480

acuuccaaau cagcagccaa cuacaauuca gcccagaaga aguccucgga augguccuaa      540

acuacagcag aagccucgca gaggauuucg ccgaacagcc aauaaaagac gccguaauaa      600

cagucccagu auucuucaac caagccgagc gacgagccgu ccuacaggca gcacgcaugg      660

ccgggcucaa gguacuccag cuaauaaacg acaacacggc aacggcccua uccuacggag      720

ucuuucggag aaaagacaua aacacaaccg cacaaaacau aauguucuac gacaugggcu      780

caggcucgac agucugcaca auagucacau accagauggu caaaacaaag gaagccggga      840

ugcaaccgca acugcaaaua cgaggagucg gauucgaccg aacacuggga ggacuagaaa      900

uggaacuacg acuccgagag aggcuggccg gccuauucaa cgaacaaaga aaaggccaac      960

gcgcaaaaga cguaagggaa aacccacgag caauggcuaa acuacuccga gaagccaacc     1020

gacugaaaac aguacuaagc gcaaacgcag accacauggc gcaaauugaa gggcuaaugg     1080

acgacguaga cuucaaagca aaagucaccc gcguggaguu cgaggaacuc ugcgcagacc     1140

uguuugaacg cguccccggc cccguacaac aagcacugca aagcgcagaa augagccuag     1200

acgagauaga acaaguaauc cuaguaggcg gcgccacacg aguacccaga guucaagagg     1260

uacuacugaa agcugucggg aaagaggaac uaggcaaaaa caucaacgcc gacgaggccg     1320

cagcaauggg agccguauau caagcagcag cauuaaguaa agcauucaag guaaagccgu     1380

uuguaguacg ggacgccguc guauacccaa uuuuagucga guucacgcgg gaagucgaag     1440

aggaacccgg aauacacuca cugaaacaca acaaacgcgu ccuauucuca cgaauggguc     1500

ccuacccaca aagaaaagua auaaccuuca accgauacag ccacgacuuc aauuuccaca     1560

ucaacuacgg cgaccuugga uuccuagggc ccgaagaccu gagagucuuc ggaagccaga     1620

accucaccac agucaaacug aaaggagugg gggacagcuu caagaaauac ccagacuaug     1680

aaucaaaagg aauaaaggca cacuucaacc ucgaugaaag cggaguacug agccuggaca     1740

ggguagaaag cguuuucgag acacuggugg aagacagugc cgaagaagag agcacacuaa     1800

caaaacuggg caacacaauc aguagccucu ucgggggcgg aacaacgcca gacgcaaaag     1860

aaaacgggac cgacaccgua caagaagaag aagaaagccc agccgaagga agcaaggacg     1920

agccaggaga gcagguagag cucaaagaag aagcagaggc gcccguagaa gacggcucuc     1980

agccaccucc gcccgaaccc aaaggagacg caacaccaga gggagagaag gcgaccgaaa     2040

aagaaaacgg cgacaaaagc gaggcgcaaa aaccgucgga gaaagccgag gcgggaccag     2100

aaggaguagc cccagcaccc gaaggcgaaa agaaacaaaa accagcgaga aaaagaagga     2160

ugguggagga aaucggcgug gaacugguag ugcuagauuu acccgaccuc ccagaagaca     2220

aacucgcgca gucgguacag aaauuacaag accugacacu aagagaucuu gaaaaacaag     2280

aacgagagaa ggcggcaaac agucuggaag cguucaucuu cgagacgcag gacaaacuau     2340

accagccgga guaccaagag guaucaaccg aagaacaaag agaggaaauc uccggcaagc     2400

uaucggcggc cucaacaugg cucgaggaug aagggguagg cgccaccaca gugaugcuaa     2460

aagaaaagcu agcugaacua agaaaacuau gccaaggucu auuuuuccga gucgaggaaa     2520

ggaagaaaug gccagaaaga cuaucggccc ucgacaaccu acuaaaccac uccagcaugu     2580

uucuaaaagg cgcgagacua auaccagaga uggaccaaau cuucacggaa gucgaaauga     2640

ccacacuaga aaaagugaua aacgagacgu gggcauggaa aaaugccaca cucgcagaac     2700

aagccaaacu acccgcaacg gaaaagcccg uccuacucag caaagacauc gaagcaaaaa     2760

ugauggcguu agaccgcgaa guacaguacc uacuaaacaa agcgaaauuc accaaaccac     2820

gaccccgccc caaagacaaa aacggcacac gggcagagcc accacugaac gcaagcgccu     2880

cagaccaagg ggaaaagguc auacccccgg ccggacaaac cgaagacgcg gaaccaauaa     2940

gcgagcccga aaagguggag acgggaagcg aacccggcga cacagagcca cuggaacuag     3000

gaggcccggg cgcagaacca gagcaaaagg aacaaagcac agggcaaaag aggccacuca     3060

aaaacgauga acuauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4609
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt8)

<400>  4609
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaagaaa cgcaaacgca agaccaacca auggaagagg      120

aggaaguaga aacguucgcc uuccaggcag agaucgccca acuaaugagc cugauaauaa      180

acacauucua cucgaacaaa gagauauucc ucagagagcu cauaagcaac agcucggacg      240

cacuggacaa aauacgauac gaaucccuaa ccgacccgag caaacucgac uccggcaaag      300

aacuccacau caaccuaaua ccaaauaaac aggaccggac acucaccauc gucgacacag      360

ggauaggaau gacaaaagcg gaccugauca acaaccuagg aacgauugca aaaagcggaa      420

caaaagcguu cauggaagcc cuccaagcag gcgccgauau auccaugaua ggacaauucg      480

gcgugggguu cuacucagca uacuuagucg cggaaaaagu cacgguaaua acgaaacaca      540

acgacgacga acaguacgcg ugggagagcu ccgcaggcgg cagcuucaca guuaggacag      600

acaccggaga gcccaugggg cgagggacca aggucauccu ucaccucaaa gaagaccaaa      660

cggaauaccu cgaagaaagg cgcauaaagg aaaucgugaa gaaacacucc caauucauag      720

gauacccuau cacacuauuc guagaaaaag aacgcgacaa agagguaagc gacgacgaag      780

cggaagagaa ggaagacaag gaagaggaaa aagagaagga agagaaagaa agcgaagaca      840

agcccgaaau agaagacgua ggcucggacg aggaagaaga aaagaaagac ggcgacaaaa      900

agaagaaaaa gaaaauaaaa gaaaaauaca uugaccagga ggaacucaac aaaacgaaac      960

cgauauggac caggaacccg gacgacauca caaacgaaga auacggggag uucuacaaau     1020

cgcucacaaa cgacugggaa gaccaccuag cggucaaaca cuucagugug gagggacaac     1080

uagaguucag agcacuccug uucgucccaa ggcgagcccc auucgaccua uucgaaaacc     1140

gcaaaaagaa aaacaacaua aaacucuacg ucagaagagu cuuuauaaug gacaacugcg     1200

aggaacuaau ccccgaauac cuaaauuuca uccgaggggu cguggacucu gaagaccucc     1260

cacuaaacau cucaagagaa augcugcagc aaaguaagau ccuaaaagug auccgcaaaa     1320

accuaguaaa gaaaugccug gaacuguuca cggaacuggc ggaggauaaa gaaaacuaca     1380

aaaaguucua cgaacaauuc uccaagaaca uuaaacuggg gauccacgaa gacucccaaa     1440

acagaaagaa acugagcgaa cuccugcgau acuacaccag cgcguccgga gacgagaugg     1500

ucagccuaaa ggacuacugc accagaauga aagaaaacca aaaacacauc uacuauauaa     1560

caggggaaac caaggaccaa gucgcaaaca gcgccuuugu agagcgccug agaaaacacg     1620

gacucgaagu cauauacaug auagaaccaa ucgacgaaua cugcguacag cagcugaagg     1680

aguucgaagg aaaaacgcua guaucgguaa cgaaagaggg acuagagcua cccgaagacg     1740

aggaagagaa aaagaaacaa gaagaaaaga aaaccaaauu cgagaaccuc ugcaaaauaa     1800

ugaaagacau ccuagaaaag aaaguagaaa aagucguagu gucaaaccgc cucgucacga     1860

gcccauguug cauagucacg ucaaccuacg gauggacagc caacauggag aggauaauga     1920

aagcccaagc ccuacgagac aacucaacaa ugggauacau ggccgccaag aaacaccuag     1980

aaauaaaccc cgaccauucg auaauagaga cucuccgaca aaaagccgag gccgacaaga     2040

acgacaagag cguaaaagac cugguaaucc uccucuacga aacggcccuc cuaucaagcg     2100

gguucagccu agaagaccca caaacccacg ccaaccgcau cuacagaaug auaaaacuag     2160

gacucggaau cgacgaagac gacccgaccg cggacgacac cucagcagcg guaacagagg     2220

aaaugccccc acuagaaggg gacgacgaca cgagcagaau ggaggaagua gacuaaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  4610
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt8)

<400>  4610
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccucaa aacuagacuc cggcaaagga cuccacauca      120

accucguccc caacaaacaa aaccaaacac ucaccauagu agacacacgc aucggcauga      180

ccaaaacaga ccucaucaac aaccucggca ccgucaccaa auccggaaca aaagccuuca      240

uggaagcacu ccaagccgac gcagacaucu ccaugaucgg acacuucggc gucggcuucu      300

acucagcaua ccucgucgcc aaaaaaguca ccguaaucuc aaaacacaac aacgacgaac      360

aauacaccug ggaauccucc gcaggcggcu ccuucaccgu acgaacagac gaauaaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  4611
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt8)

<400>  4611
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaagagg uacaccaugg ugaagaggaa gucgagaccu      120

ucgccuucca agccgaaaua gcacaauuaa ugagccugau aaucaacacc uucuacucga      180

acaaagaaau cuuccugcgc gaacucaucu cgaacgcaag cgacgcccua gacaagauaa      240

gauacgaauc acugacagac cccagcaagc uagacucagg gaaggagcuc aaaaucgaca      300

ucauuccaaa cccccaagaa cggacacuaa cccuggugga cacagggauc gggaugacca      360

aggccgaccu gauaaacaac cucgggacaa ucgccaaaag cggcaccaaa gcguuuaugg      420

aggcccuaca agccggagcc gacaucagca ugaucgggca auucggcguc ggauucuaca      480

gcgccuaucu aguagcggaa aaaguaguag ugaucacaaa acacaacgac gacgaacaau      540

acgccuggga aagcagugca ggaggcagcu ucacggugcg agccgaucac ggagaaccca      600

uaggacgggg caccaaggug auacugcacc ucaaagaaga ccaaaccgaa uaccuggaag      660

aacgacgagu aaaggagguc guaaagaagc acagccaauu cauaggcuac ccaauaaccu      720

uguaccuaga gaaagaacgg gaaaaagaga uaagugacga cgaagcugaa gaagaaaaag      780

gcgaaaaaga agaagaagac aaagacgacg aagaaaagcc caaaaucgag gacguaggca      840

gcgacgaaga agacgacagc ggaaaagaca agaaaaagaa aacaaagaaa auaaaagaga      900

aguacaucga ccaagaagaa cucaacaaaa cgaagcccau auggacaaga aauccagacg      960

auaucacgca agaagaauac ggagaguucu auaagagucu aaccaacgac ugggaagacc     1020

accuagcggu caaacacuuc agcgucgaag gacagcuaga guuccgagcc cugcuauuca     1080

ucccccgaag ggcacccuuc gaccuauuug aaaacaaaaa gaagaaaaac aacauuaaac     1140

ucuacguacg ccgcgucuuc auaauggaca gcugcgacga acuaauacca gaauaccuga     1200

acuucauccg cggagucguc gacagcgaag accuaccacu gaacauauca cgagaaaugc     1260

ugcaacaaag caaaauccuc aaagucauac gcaaaaacau cguaaagaaa ugccuugaac     1320

uauuuucgga acuggcagaa gacaaagaaa auuacaagaa auucuacgaa gccuucagca     1380

aaaaccucaa acugggaauc cacgaagacu ccacaaaccg aagaagacua agcgaacucc     1440

uaagauacca caccagucaa agcggcgacg aaaugacaag ccucucagaa uacguguccc     1500

gaaugaaaga aacccagaaa agcaucuacu acaucacggg cgaaagcaaa gaacaaguag     1560

caaacagugc uuucguagaa cgggugagaa agcgaggauu cgaagucgug uauaugaccg     1620

aaccaaucga cgaauacugc guacaacaac uaaaagaguu cgauggcaag ucccucguau     1680

cagucacgaa agaaggccua gaacugccgg aagacgaaga agagaaaaag aaaauggaag     1740

aaagcaaagc aaaauucgaa aaccugugca aacucaugaa agaaauacuc gacaagaaag     1800

ucgaaaaagu aacaauaagc aaccggcuag ugagcagccc augcugcauc gucacaagca     1860

cauacggcug gacggcgaac auggaaagaa uaaugaaagc acaagcccua cgagacaaca     1920

gcacgauggg auacaugaug gcaaagaagc accuagaaau caacccagac cacccaaucg     1980

uggaaacacu ccgacaaaaa gccgaagcag acaagaacga caaggccgua aaagaucuag     2040

ugguacuacu guucgaaacc gcgcuacuca gcucaggauu cagccucgag gacccacaaa     2100

cccacucgaa caggaucuac agaaugauca aacuaggccu gggaauagac gaagacgaag     2160

ucgccgccga agaacccaac gcggcagucc cagacgaaau cccaccauug gagggagacg     2220

aagacgcaag caggauggag gaaguagacu aaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  4612
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt8)

<400>  4612
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agggcguuau ggguccuagg gcugugcugc guccuccuga      120

cguucggcag cgucagagca gacgacgaag uggacguaga cggcaccgua gaagaagacc      180

ugggaaaauc cagagagggu agcagaaccg acgaugaagu cgugcagcga gaggaagaag      240

ccauccaacu cgacgggcug aacgcgucac agauacggga acuacgagag aaaagcgaaa      300

aauucgccuu ccaagcagaa gucaaccgaa ugaugaaguu aaucauaaac ucacuauaca      360

aaaauaaaga aauauuccuc agagaacuga uaagcaacgc gagugacgca cuagacaaaa      420

ucagacucau cagccucacc gacgaaaacg cccuuagugg gaacgaagaa cuaacaguca      480

aaaucaaaug cgacaaggaa aagaaccuac uacacguaac agacacgggu guaggaauga      540

cccgggagga acucgucaaa aaccucggca ccauagcgaa aagcggaaca ucagaguucc      600

ucaacaaaau gacagaggcc caggaagacg gacaaagcac cagcgaacug aucgggcaau      660

ucggaguagg auucuacagc gcguuccucg uggcagauaa ggucaucguc accucaaaac      720

acaacaacga cacccagcac auaugggaga gcgacagcaa cgaguucucc guaaucgcgg      780

acccccgcgg gaacacgcuc ggccgcggaa ccacaaucac acucguacuc aaagaagaag      840

caagcgacua ccuagagcuc gauacaauaa agaaccuggu gaaaaaguac agccaguuca      900

ucaacuuccc aaucuacgua uggagcagca aaacugagac gguagaagaa ccaauggaag      960

aagaggaagc agccaaagaa gaaaaagaag agucggacga cgaggcagcg guagaagaag     1020

aagaagaaga gaagaaaccg aaaaccaaga aaguagagaa aacgguaugg gauugggaac     1080

uaaugaacga caucaaaccc auauggcagc gccccagcaa agaagucgaa gaagacgaau     1140

acaaggcauu cuacaagagc uucagcaaag aaagugacga cccgauggcc uacauacacu     1200

ucaccgcaga aggggaagua acauucaaga gcauacuauu cgucccaacc ucagcgccgc     1260

gaggacucuu cgacgaguac gggagcaaga aaagcgacua caucaaacug uacguaagac     1320

gcguauucau aaccgacgac uuccacgaca ugaugcccaa auaccuaaac uuugugaaag     1380

ggguaguaga cagcgacgac cuaccccuaa acguguccag agaaacccuc cagcagcaca     1440

aacuccugaa gguaauaagg aagaaacugg ugcggaaaac acuagacaug auaaagaaaa     1500

uagccgacga caaguacaac gacaccuucu ggaaggaguu cggcaccaac auaaaacuag     1560

gggugaucga agaccauagc aaccggaccc gacucgcaaa acuccuaaga uuccaaucaa     1620

gccaccaccc caccgacaua acgagccucg accaguacgu ggaaaggaug aaggaaaagc     1680

aagauaaaau cuacuuuaug gcgggcuccu cccgaaaaga agcagaaagc ucacccuucg     1740

uagagcgacu acucaagaaa ggguacgaag uuauauaccu gacagaaccu guggacgaau     1800

acugcauaca agcacugccg gaguucgaug gcaaacgcuu ccaaaacgug gcaaaagaag     1860

gcguaaaauu cgacgaaagc gagaaaacga aagaaucacg cgaagcagua gaaaaagagu     1920

ucgaaccccu acucaauugg augaaagaca aagcauuaaa agacaaaaua gaaaaagcag     1980

uagugagcca acgcuugacc gaaagcccgu gugcccucgu agcaagccag uacggcugga     2040

gcgggaacau ggagagaauc augaaagcgc aggcguacca aacaggaaaa gacauaucca     2100

ccaacuacua cgcuucacaa aagaaaaccu ucgaaauaaa cccaagacau ccgcuaaucc     2160

gcgacaugcu gcgacgaaua aaggaggacg aagacgacaa gacaguacuc gaccucgcag     2220

ucguccucuu cgaaaccgca acgcuacggu caggcuaccu gcucccagac acgaaagcau     2280

acggagacag gauagagagg augcucagac uaagccuaaa cauagacccg gacgccaagg     2340

uagaagaaga accagaggaa gaaccggaag aaacggcaga agacaccaca gaggacacag     2400

agcaagacga ggacgaggaa auggacguag gaacugauga agaagaagaa acggccaaag     2460

aaucgacagc agaaaaggac gaacuauaag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  4613
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt8)

<400>  4613
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacgagaac uaagggcccu ccuccuuugg ggccgacgcc      120

uccgcccgcu acuucgcgcg ccagcacugg cagcuguccc aggaggcaaa cccauccuau      180

gcccccgccg aacaaccgca cagcucgguc ccagacgcaa cccagcuugg ucccuucaag      240

caggccgccu cuucuccacu caaacagcag aagacaaaga agaaccacuc cacagcauaa      300

ucucaucaac cgaaucagua caaggcucaa caucuaaaca cgaguuccaa gccgaaacua      360

agaaacugcu cgacauagug gccagauccc uauacuccga aaaagaaguc uucauccgcg      420

aauugaucuc aaacgcaucc gacgcacucg aaaaacuacg acacaaacuc gucuccgacg      480

gccaagcccu cccagaaaug gaaauccauc ugcaaacuaa cgccgaaaaa ggcaccauaa      540

caauccagga cacaggcauc ggcaugaccc aagaggaacu ugucuccaac cucggaacaa      600

ucgcccgcag cggauccaaa gcauuccucg acgcccuaca aaaccaagca gaagcaagcu      660

ccaaaaucau cggacaauuc ggagucggcu ucuacucagc cuucaugguc gccgaccgcg      720

ucgaagugua cucacgcuca gcugcacccg gaagucuagg cuaucaaugg cuaucagacg      780

gaagcggggu cuucgaaauc gcagaagccu cuggcgugcg cacaggcacc aaaaucauca      840

uccaccugaa auccgacugc aaagaguucu cgagcgaagc acgagucagg gacguuguaa      900

ccaaauacuc aaacuucgua uccuuuccac uauaccucaa uggccgucga augaacaccc      960

uccaagcaau cuggaugaug gacccuaaag acguaagaga auggcaacac gaagaguucu     1020

accgcuacgu ugcccaagcu cacgacaaac cacguuacac ccugcacuac aaaaccgacg     1080

caccccugaa uauccgaagc auuuucuacg uccccgacau gaaacccucu auguucgacg     1140

uaucccgcga acucggcucc ucagucgccc uauacucccg caaaguccuu auacaaacca     1200

aagccaccga cauacuccca aaauggcucc gcuuuauacg aggagucguc gacucagaag     1260

acaucccgcu caaccugagc cgagaacuac uccaagaauc cgcccucauu cgcaaacugc     1320

gugacguccu ccaacaacgc cucaucaaau ucuucaucga ccaaucaaag aaagacgccg     1380

aaaaauacgc uaaauucuuc gaagacuacg gccuauucau gcgcgaagga aucgugaccg     1440

ccacagaaca agaggucaaa gaagacauag ccaaacuccu aagauacgaa uccuccgcac     1500

ugcccucggg acaauuaacc ucacuauccg aauacgcaag ccguaugcgc gccgggaccc     1560

gcaacaucua cuaccucugc gcccccaacc gacaccuggc agagcacucc ccauacuacg     1620

aggcaaugaa aaagaaagac accgaagucc uuuucugcuu cgaacaauuc gacgaacuaa     1680

cccucuuaca ccuaagggag uucgacaaaa agaaacucau cucaguggaa acggacaucg     1740

uagucgacca cuacaaagaa gaaaaauucg aagaccgcuc accagccgca gaaugucuau     1800

ccgaaaaaga aacagaagaa cucauggccu ggaugcgcaa cguccuaggc agucgcguca     1860

caaacgucaa aguaacccuu agacuugaca cccaucccgc caugguaaca guccucgaaa     1920

ugggagccgc acgccacuuc cuaagaaugc agcaacuagc caaaacacaa gaagaaagag     1980

cccaacuccu acaaccuaca cuagaaauca acccccgcca cgcacucauc aagaaacuaa     2040

accaacuacg cgcaagcgaa ccaggccuag cgcaacuccu aguagaccaa aucuacgaaa     2100

acgccaugau agcagcaggc cuaguagacg acccccgcgc cauggucggc cgccucaacg     2160

aacuccuagu aaaagcccuc gaaagacacu aaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  4614
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt8)

<400>  4614
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaaaucu ccucacuccc cacacaacua uucaaaugcu      120

gcuucugcga cuuccucaaa gucaaaaugc acacaauguc cuccucacac cucuucuacc      180

uagcccucug ccuacucacc uucacaucau cagccacagc cggcccugaa accuuaugcg      240

gagccgaacu cguagacgcc cuccaauucg ucugcggaga ccgaggcuuc uacuucaaca      300

aacccaccgg uuacggauca ucaucccgcc gcgccccaca aacaggcauc gucgacgaau      360

gcugcuuccg cucaugcgac cuccgaagac uagaaaugua cugcgcaccc cucaaacccg      420

ccaaauccgc ccgcuccguc cgagcccaac gccacacaga caugcccaaa acacaaaaag      480

aaguccaccu caaaaacgcc ucccgaggau ccgccggcaa caaaaacuac cgcauguaag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  4615
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt8)

<400>  4615
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcauaccaa ugggcaaauc caugcuagua cuccuaaccu      120

uccuugccuu cgcauccugc ugcauagccg ccuaccgacc cuccgaaaca cucugcggcg      180

gcgaauuagu cgacacccua caauucgucu gcggcgaccg cggcuucuac uucucccgac      240

cagccucccg cgucuccaga cgcucacgcg gcaucguaga agaaugcugc uuccgaucau      300

gcgaccucgc ccuccucgaa accuacugcg ccacccccgc aaaaucagaa cgagacgucu      360

caaccccacc caccguccuc cccgacaacu uccccagaua ccccguaggc aaauucuucc      420

aauacgacac cuggaaacaa uccacccaaa gacuuagacg cggccucccc gcccuacucc      480

gagcccgccg cggacacgua cucgccaaag aacucgaagc cuuccgcgaa gccaaacgcc      540

accgcccacu caucgcccua cccacacaag accccgccca cggcggcgca cccccagaaa      600

uggccucaaa ccgaaaauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  4616
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt8)

<400>  4616
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccacaucagc cuucggcccc gucgccuucu      120

cccucggacu ccuccuuguc cucccagccg ccuuccccgc cccagucccc cccggcgaag      180

acucaaaaga cguagccgcc ccccaccgac aaccccuuac cuccuccgaa cgcaucgaca      240

aacaaauacg auacauccua gacggcaucu cagcccuccg caaagaaacc ugcaacaaau      300

ccaacaugug cgaaucuucc aaagaagccc uagccgaaaa caaccucaac cuccccaaaa      360

uggccgaaaa agacggcugc uuccaaucag gauucaacga agaaaccugc cuugucaaaa      420

ucaucaccgg ccuccucgaa uucgaagucu accucgaaua ccuccaaaac cgcuucgaau      480

cauccgaaga acaagcccgc gccguccaaa ugucaacaaa aguccucaua caauuccucc      540

aaaaaaaagc caaaaaccuc gacgccauaa ccacccccga ccccaccacc aacgccucac      600

uacuaaccaa acuccaagcc caaaaccaau ggcuacaaga caugaccacc caccucaucc      660

uccgcuccuu caaagaauuc cuacaaagcu cccuccgcgc ccuacgccaa auguaaggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  4617
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt8)

<400>  4617
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuacuau ggcuccgcgg cuuccuacug gccucaugcu      120

ggaucaucgu acgcagcagc cccacaccag gaagcgaggg acacagcgca gccccagacu      180

gcccaagcug cgcccuagcg gcccugccaa aagacguacc caacagccaa cccgaaaugg      240

uagaagccgu caaaaaacac auacuaaaca ugcuacaccu aaaaaaaagg ccagacguaa      300

cacaacccgu cccaaaagca gcacuacuca acgcaauccg caaacuccac gucgggaaag      360

ucggagaaaa cggauacgua gagauagaag acgacaucgg gcgccgcgcc gaaaugaacg      420

aacucaugga acaaaccuca gagauaauca cguucgccga aagcggaaca gcccgcaaaa      480

cacuacacuu cgaaauaagc aaagaaggca gcgaccuaag cgucgucgag cgcgcagaag      540

ucuggcucuu ccucaaagua cccaaagcaa accgcacacg aacaaaaguc acaauacgac      600

uguuccagca acaaaagcac ccacaaggcu cccucgacac aggcgaagaa gcagaagaag      660

uaggccuaaa aggagaacgg agcgaacuac uccuaucaga aaaagucgua gacgcacgca      720

aaagcacgug gcacgucuuc ccaguaagca gcagcauaca acgacuacuc gaccaaggca      780

aaagcagccu cgacgucaga auagcaugcg aacaaugcca agaaucaggc gccucccucg      840

uccuacuggg aaaaaaaaag aaaaaagaag aagaaggcga aggaaagaaa aaaggcggug      900

gagaaggagg cgcaggagcg gacgaggaaa aagaacaauc ccaccgccca uuucuaaugc      960

ugcaagcacg gcaaucagaa gaccaccccc accgccgccg acgacgagga cuagaaugcg     1020

acggaaaagu caacaucugc ugcaaaaaac aauucuucgu cagcuucaaa gacauaggau     1080

ggaacgacug gauaauagcg ccaagcggau accacgcaaa cuacugcgaa ggcgaaugcc     1140

ccagccacau agcaggcaca agcgggagca gccugucguu ccacagcacc gugaucaacc     1200

acuacagaau gagaggacac uccccauucg caaaccugaa aucgugcugc guccccacca     1260

aacuacgacc gaugagcaug cucuacuacg acgacggaca gaacaucaua aaaaaagaca     1320

uacaaaauau gaucguggaa gagugcggau gcagcuaagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  4618
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt8)

<400>  4618
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccugc caggccgagc guuaggcgcc gccugccucc      120

uacuccuagc agcaggcugg cucggccccg aagccugggg aucaccaacc ccaccaccaa      180

cccccgcagc cccuccccca cccccaccac ccggcagucc cggcggauca caagauaccu      240

gcaccucaug cggcggauuc cgcagaccag aagaacucgg acgcguagac ggagacuucc      300

ucgaagccgu aaaaagacac auacuauccc gccuccaaau gcgcggccga cccaacauca      360

cacacgccgu ccccaaagcc gccaugguca ccgcccuacg caaacuacac gccggcaaag      420

uucgcgagga cggccgaguc gaaaucccac accucgacgg ccacgccucc cccggcgcag      480

acggacaaga acgaguuagc gaaaucaucu ccuuugccga aacagacggc cuagccucau      540

cacgaguccg acucuacuuu uucaucucca acgaaggaaa ccaaaaccuc uucgucguac      600

aagcaucccu auggcuauac cuaaaacucc uacccuacgu cuuagaaaaa ggaucccgcc      660

gcaaaguccg cgucaaaguc uacuuccaag aacagggcca cggcgaccgc uggaacaugg      720

ucgaaaaacg cguagaccuc aaacgcuccg gcuggcacac cuucccccua accgaagcca      780

uccaagcccu cuucgaacgc ggcgaacgac gccuaaaccu cgacguacag ugcgacucau      840

gccaagaacu cgccguagua cccguauucg ucgacccagg ggaagaaagc cacagaccau      900

ucgucgucgu ccaagccaga cucggcgacu cccgacaccg cauacgcaaa cgaggccucg      960

aaugcgacgg ccgcacaaac cucuguugcc gccaacaauu cuucaucgac uuccgccuaa     1020

ucgguuggaa cgacuggauu auagccccaa caggauacua cggcaacuac ugcgaagggu     1080

caugccccgc cuaccuagcc ggaguccccg gcucugccag cucauuccac acagcagucg     1140

ugaaccaaua ccgcaugcga ggccuaaacc ccggcaccgu aaacucuugc ugcaucccca     1200

caaaauuauc aaccaugucc augcuuuacu ucgacgacga auacaacaua gucaaacgcg     1260

acguccccaa caugauagua gaagaaugcg gcugcgccua aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  4619
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt8)

<400>  4619
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacuucgcg uccuccuccu uaccgcccua acccuauguc      120

auggauucaa ccucgacacc gaaaaugcca ugaccuuuca agaaaacgcc cgcggauucg      180

gccagucugu aguacagcuc caaggaucua gaguagucgu cggugccccu caagaaaucg      240

uagcagcaaa ccaacgcggu agucuauacc aaugugacua cucuacuggc ucgugcgaac      300

cuaucaggcu ccaagucccc guggaagccg ucaacauguc cuuaggacua ucacuggccg      360

ccaccaccuc cccaccgcaa cuccuagccu gcggacccac cguacaccaa acauguagcg      420

aaaacacgua cgucaaagga cucuguuuuc ucuucggcag caaccuacgc caacaacccc      480

aaaaauuccc ugaagcccuc agaggcugcc cacaagaaga cuccgacaua gccuuccuca      540

ucgacggauc cggcuccauu auaccccacg acuuccggag gaugaaagaa uuugucucga      600

cgguaaugga gcaacucaag aaaucaaaaa cacuguucag ccuaaugcaa uacucggagg      660

aguuccgaau ccacuucacc uucaaagagu uccaaaacaa ccccaacccc cguagccuug      720

uuaaacccau aacccaacua cugggccgaa cacacaccgc caccggcauc cgcaaagucg      780

uccgcgaacu auucaacaua accaacggcg cacgcaaaaa ugcuuucaag auacuuguag      840

uaaucacaga cggagaaaaa uucggagacc cauugggaua cgaagacguc auuccugaag      900

ccgaccgaga aggcguaauc agauacguga uagguguagg cgacgcauuc agaucagaaa      960

aaucacgcca agaacuaaac acaauagccu ccaagccacc ccgagaccau gucuuccagg     1020

uaaacaauuu cgaggcacuu aaaacuauuc agaaccagcu ccgugagaaa aucuucgcca     1080

ucgaaggaac ucagacagga uccuccucgu cuuucgaaca ugagaugagc caagaaggcu     1140

ucagcgcugc caucaccucu aacggacccu ugcuaucuac agucggcucc uacgacuggg     1200

ccggcggcgu guuccucuac accuccaaag aaaaauccac guucauaaac augacacgag     1260

ucgacucgga caugaaugac gcguaccuug guuaugcugc cgcaauuaua cuuagaaacc     1320

gugugcaauc ccuuguacuc ggcgcuccca gauaucaaca caucggccuc gucgcuaugu     1380

uucgucaaaa uaccgggaug ugggaaucca acgccaaugu caaaggcacc caaaucggcg     1440

ccuacuucgg cgcgagccua ugcucagucg acgucgacuc aaacggaucc accgaucuag     1500

uccugaucgg agcaccacac uauuacgaac aaaccagagg cggccaggua ucagucugcc     1560

cacucccccg aggccgcgcc cgcuggcaau gcgacgccgu ccuuuacggc gagcagggcc     1620

agccuugggg acgauucgga gccgcccuca ccguacucgg ugacguuaac ggagauaaac     1680

uaacagacgu cgcaaucggc gcccccggag aagaagacaa cagaggagcg gucuaccucu     1740

uucacggaac cuccgggagc ggaaucagcc cgucccauuc ccagcgcauu gcagguagca     1800

aacucagucc ccgccuccag uacuucggcc aaucccuguc cggcggccaa gaccuuacaa     1860

uggacggccu aguagaccuc accgucggug cucagggcca uguccugcuu cuacgcucuc     1920

aaccagucuu acgaguaaaa gcaauaaugg aguucaaccc acgcgaaguc gcccgcaacg     1980

ucuucgaaug caacgaccag gucguaaaag gcaaagaagc cggagaaguc cguguaugcc     2040

ugcacguaca aaaguccacc cgcgaccgcc uacgggaagg ccaaauacag ucugucguca     2100

cuuaugaccu cgcucucgac uccggaagac cgcacucucg ggccgucuuu aacgaaacca     2160

aaaacucaac acgacgacaa acacaggugc ucggccugac gcagacaugc gagacgcuca     2220

aauugcagcu accaaacugc aucgaagacc caguaagccc uauuguccuu cgccuaaacu     2280

ucagccucgu ggggacacca cuaagcgccu ucggcaaccu acgcccggua cucgcggaag     2340

acgcccagcg ccucuucacc gcccuuuuuc ccuucgagaa aaacugcggc aacgauaaca     2400

ucugccaaga cgaucugucg aucaccuuca gcuucauguc ccucgacugu cucguagucg     2460

gaggcccccg ugaguucaac guaaccguaa ccguccgcaa cgacggagaa gacagcuacc     2520

gcacucaggu caccuuuuuc uucccccucg accugucuua cagaaaagua ucaacacucc     2580

aaaaccaacg aucccaacgu ucauggcgac uagccugcga auccgccagc uccacugaag     2640

ucagcggcgc ccucaaaagc acguccugcu cgaucaacca ccccauauuc cccgagaacu     2700

cagaagucac auucaacauc acauucgacg uagauucaaa ggcuucacuc ggaaauaaac     2760

ugcuucucaa agccaacguc accucagaaa auaauaugcc ccguacuaac aaaaccgagu     2820

uucaacuaga acucccgguc aaauacgccg ucuacauggu aguaaccucu cacggaguau     2880

ccaccaagua ccucaacuuc acugcauccg aaaacacuuc ucgcgucaug cagcaccaau     2940

aucaagucuc caaccucggu caacguucac ugcccaucuc ccuaguauuc cuggucccag     3000

uacgccuaaa ccagaccguc auaugggaca gaccccaagu caccuucuca gaaaaccuua     3060

gcucuaccug ccauacaaag gaaagauuac ccucacacuc cgacuuucuc gcagagcuca     3120

ggaaagcccc cguagucaac ugcucgauag caguaugcca acgaauacaa ugcgauaucc     3180

cauucuuugg cauccaggaa gaguucaacg ccacccugaa ggguaaccuc ucauucgacu     3240

gguacauaaa gacaucacau aaccaucuac uuauagucag cacagccgaa auccuguuca     3300

acgacucagu guucacccuc cugcccggcc aaggagccuu cguacgcuca caaaccgaaa     3360

caaaaguuga accuuucgaa guucccaacc cccuuccgcu cauagucggc uccucagucg     3420

gaggccuccu ccuacucgcc cuaauaaccg cagccuugua caaacucgga uucuucaaac     3480

gccaguacaa agacaugaug ucagaaggag guccucccgg cgcagaacca caauagggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  4620
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt8)

<400>  4620
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucacuaa aaacccuacc cuuucuccua cuccuucacg      120

uccagauauc aaaagccuuc cccgucuccu cuaaagagaa aaacaccaaa accgugcaag      180

acuaccucga aaaauucuac caacucccgu ccaaccaaua ccaaucaaca cgcaaaaacg      240

gcacuaacgu aaucgucgaa aaauugaaag aaaugcaacg auucuucggc cucaacguca      300

ccggcaaacc caacgaagaa acccucgaca ugaugaagaa accccgaugc ggaguacccg      360

acucuggcgg cuucaugcuc acucccggca aucccaaaug ggaacgcacu aaccucaccu      420

accgcaucag aaauuacaca ccccaacucu cagaagccga agucgaaaga gcgauuaaag      480

acgcauucga acuauggucc gucgccagcc cccuaaucuu cacccgcauc ucccaaggug      540

aagccgacau caacauagca uucuaccaac gcgaccacgg ugacaacucc ccauucgacg      600

gcccaaacgg cauacuugcc cacgcauucc aacccgguca aggaaucgga ggcgacgccc      660

acuucgacgc cgaagaaacc uggaccaaca cauccgcaaa cuacaaccua uuccucguug      720

ccgcccacga guucggccac ucccuaggcu uagcacacuc cuccgaucca ggugcccuaa      780

uguauccaaa cuacgccuuc cgcgaaaccu ccaauuacuc ccuaccccaa gaugacaucg      840

acggaaucca agcaaucuac ggacucucau ccaaccccau ccaacccacc gguccaucaa      900

ccccaaaacc cugcgacccc ucccucaccu ucgacgcaau caccacucuc agaggugaaa      960

uccucuucuu caaagaccgu uacuucuggc gaagacaccc acaacuccaa cgcgucgaaa     1020

ugaacuuuau uucacucuuc uggcccucgc uucccaccgg cauccaggcc gcauacgaag     1080

acuucgaccg cgaccuaauc uuccucuuca aagguaacca auacugggca cuaucaggcu     1140

acgacauccu ucaaggcuac cccaaagaca uauccaacua cggcuuccca uccuccgucc     1200

aggcaaucga cgcugcaguc uucuauagau ccaaaaccua cuucuucguc aacgaccaau     1260

ucuggcgaua cgacaaccaa cgacaauuca uggaacccgg cuaccccaaa ucaaucuccg     1320

gcgcuuuccc cggcaucgaa uccaaagucg acgccguuuu ccaacaagaa cacuucuucc     1380

acgucuucuc cgggccacga uacuacgccu ucgaccucau cgcccaacgc gucacccgag     1440

uagcacgcgg caacaaaugg cuuaacugcc guuacggcug aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  4621
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt8)

<400>  4621
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucccucuggc aaccccuagu ucuaguccuc cucguacuug      120

gaugcugcuu cgcagcaccc cgacaacgcc aauccacccu aguccucuuc ccuggcgauc      180

uucgaacaaa ccugaccgac cgccaacucg cggaagaaua ucucuaccgc uacggcuaca      240

cacguguagc cgaaaugcgc ggagaaucca aaagccuagg uccagcacuc cuccuccucc      300

aaaaacaacu uucacucccc gaaacgggcg aacucgacuc cgccacccuc aaagcaauga      360

gaacaccacg cugcggggua cccgacuuag ggagauucca aacguucgaa ggagaccuaa      420

aguggcacca ccacaacaua acuuacugga uacaaaacua cagcgaggac cugccccgag      480

cagucaucga cgacgccuuc gcaagagccu ucgcccuaug gagcgccgua acaccccuca      540

ccuucacccg uguauacucc cgagacgccg acauugucau ccaauucggc guagccgaac      600

acggagacgg cuacccauuc gacggcaaag acggccuauu ggcacacgca uuuccacccg      660

gcccaggaau acaaggcgac gcccacuuug acgaugacga acucuggagc cugggaaaag      720

gagucguagu ccccaccaga uucggcaacg cagacggagc agcaugccac uuccccuuua      780

uauucgaagg ccgcucuuac agcgccugca cuaccgaugg ccgcuccgau ggucuacccu      840

ggugcuccac caccgccaac uacgacaccg augaucgcuu cgguuucugu ccaucugaaa      900

gacucuacac ccaggacggc aacgccgacg gcaaacccug ccaauuucca uucaucuucc      960

aaggccaauc uuacuccgca ugcaccacag acggccgauc cgauggauau cgcuggugcg     1020

ccacaacugc caauuacgac cgagacaaac ucuucggauu cugcccaacc cgagcagacu     1080

caaccguaau gggaggaaac ucagccggcg aauuaugcgu auuucccuuc accuuccucg     1140

gaaaagagua cuccacgugc accagcgaag gccgaggaga cggacgacua uggugcgcca     1200

ccacaucaaa cuucgacucc gacaagaaau ggggcuucug ccccgaucaa ggcuacucuc     1260

uguucuuagu cgccgcacac gaguucggac acgcccuggg acuagaccac aguucagucc     1320

ccgaagcgcu cauguacccc auguaccgcu ucacagaagg accaccacua cacaaggacg     1380

acguaaacgg caucagacac cuauaugguc cccgaccaga acccgaacca cgcccuccca     1440

cuaccacuac cccacaacca acugccccac ccacaguaug uccaacagga ccacccaccg     1500

uacaccccuc cgaacgcccc accgccggcc cuaccggacc ucccuccgca ggucccacag     1560

gaccacccac agccggcccc uccaccgcca ccacaguucc cuuauccccu gucgacgacg     1620

caugcaacgu caacauauuc gacgcuaucg ccgaaaucgg caaucaacua uaccuguuca     1680

aggacggcaa auauuggcgc uucucagaag gccgaggcag ccgcccucaa gguccauucc     1740

ucauugccga caaauggccc gcccucccca gaaaacuuga cuccgucuuc gaagaacguc     1800

ucuccaagaa auuauucuuc uucucaggcc gucaagucug ggucuacacc ggcgccagcg     1860

uccucggccc cagacgucua gacaaacuug gacucggagc cgacgucgcu cagguaaccg     1920

gggcucugcg auccggacgc gggaagaugu ugcuauucag cggacgcaga cuauggcgcu     1980

ucgacgucaa agcccaaaug gucgacccga gauccgccuc cgaaguugac cguauguucc     2040

caggcgugcc ccucgacacc cacgacguau uccaauaccg cgaaaaagca uacuucugcc     2100

aggaccgcuu uuauuggcga gucucuuccc gaucugaacu uaaccaaguc gaccaaguag     2160

gauaugucac cuacgacauc cuccagugcc ccgaggacua aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  4622
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt8)

<400>  4622
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacccaggcg uccucgcagc uuuccucuuc cucuccugga      120

cacacugccg cgcauuaccc cuccccucag gaggcgacga agacgaccuc uccgaagagg      180

accuccaauu cgccgaacgu uaccuccgcu ccuacuacca cccgacaaac cucgcaggaa      240

uacucaagga aaacgccgcc uccuccauga ccgaacgccu uagagaaaug cagucauucu      300

ucggccuaga aguaaccgga aaacuagacg acaacacccu agacgucaug aaaaaacccc      360

gaugcggugu ccccgacguc ggcgaauaca acgucuuccc ccgcacccuu aaguggucca      420

aaaugaaccu gaccuaucgc auagucaacu acacgccaga caugacccau uccgaagucg      480

aaaaagcauu caaaaaagcg uucaaaguau gguccgacgu caccccacuu aacuucacac      540

gccuccacga cggaaucgca gacaucauga uaagcuucgg uaucaaagaa cacggcgacu      600

ucuaccccuu cgacggccca ucaggccuac uagcccacgc auuccccccc ggcccgaauu      660

acggcggcga cgcccacuuu gacgaugacg aaaccuggac auccuccucc aaagguuaca      720

accuauuccu aguagccgca cacgaauucg gccacucccu cgggcuagac cacuccaaag      780

accccggagc ccucauguuc cccauauaca cuuacaccgg caaaucccac uucaugcuac      840

ccgacgacga cguacaaggc auccaauccc uguacggccc aggcgacgaa gacccaaacc      900

ccaaacaccc caaaacuccc gacaaaugcg accccucccu cucccuagac gccaucaccu      960

cacuccgcgg cgaaacaaug auauucaaag accguuucuu cuggcgccuc cacccacaac     1020

aaguagaugc agaacucuuc cuaacaaaau ccuucuggcc cgaacuacca aaccgaaucg     1080

acgcugcaua ugaacaucca ucccacgacc ucauuuucau auuucgaggc cgaaaauucu     1140

gggcacuaaa cgguuacgac auccucgaag gcuaccccaa aaaaaucucc gaacuaggcc     1200

uucccaaaga aguaaaaaaa aucucagccg ccguccacuu ugaagacacc ggaaagacuc     1260

uacuauucuc aggcaaccaa gucuggcgau acgacgacac caaccacaua auggacaaag     1320

acuaccccag gcuaauagaa gaagacuuuc caggcaucgg agacaaagua gacgccguau     1380

acgagaaaaa cggcuacauc uacuucuuca acggccccau acaauucgag uacuccaucu     1440

gguccaaucg aaucguacgc gucaugcccg ccaacucaau ccucuggugc uaaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4623
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt8)

<400>  4623
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acaccacaga agacuacgac accaccaccg      120

aauucgacua cggugacgcc acccccuguc aaaaagucaa ugaacgcgcc uucggcgcac      180

aacuacuacc gccccucuac ucgcucguuu ucguaaucgg ccucgucgga aauauacucg      240

ucguccucgu ccuaguccaa uacaaacgcc ucaaaaacau gacuucaauc uaccuccuua      300

accuagccau cucugaccuc cucuuccuau ucacacuccc auuuuggauc gauuacaaac      360

ucaaagacga cugggucuuc ggcgacgcaa ugugcaaaau ccuaucaggc uucuacuaca      420

ccggccuaua uagcgaaauc uucuucauua uccuucucac caucgaccgc uaccucgcca      480

uaguccacgc agucuucgcc uugcgcgcac gcaccguaac uuuuggaguc auaaccucca      540

ucaucauuug ggcucucgcc auccucgccu caaugcccgg ccuauacuuc uccaaaacac      600

aaugggaauu cacccaccau acuugcuccc uccacuuccc acacgagucc cuaagagaau      660

ggaaacucuu ucaagcacuc aaauuaaacc ucuuuggucu cguucuuccc cuccucguca      720

ugauaauuug cuacaccggc aucaucaaaa uccuccuccg ccguccaaac gaaaaaaaau      780

ccaaagccgu ccgccuaauc uucguaauaa ugaucaucuu cuuccucuuc uggacccccu      840

acaaccucac aauccucauc uccgucuucc aagauuuccu cuucacccac gaaugcgaac      900

aaucucguca ccucgaccuc gcuguccaag ucacagaagu caucgcuuac acacacugcu      960

gcgucaaccc cguaaucuac gcauucgucg gugaacgauu ccgcaaauac cuccgccaac     1020

ucuuccaccg ccgcguagcc guccaccucg ucaaauggcu ucccuuccuc uccgucgacc     1080

gacucgaacg cguaucuagc accuccccuu ccacaggaga acacgaacuc uccgccggcu     1140

ucuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  4624
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt8)

<400>  4624
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcacccucg ccugccuccu ccuccucggc ugcggcuacc      120

ucgcccacgu ccucgccgaa gaagccgaga ucccacgcga aguaaucgaa cgccucgccc      180

gcucccaaau acacuccauc cgcgaccucc aacgccuccu cgaaaucgac ucaguaggcu      240

ccgaggacuc acucgacacc ucacuccgcg cccacggcgu ccacgccacc aaacacgucc      300

ccgaaaaaag accacuccca auccgacgaa aacgauccau cgaagaagcc guccccgcag      360

ucugcaaaac ccgcaccguc auauacgaaa ucccacgauc ccaagucgac cccaccuccg      420

ccaacuuccu aaucuggccc ccaugcgucg aagucaaacg augcaccggc ugcugcaaca      480

cauccuccgu aaaaugccaa cccagccgcg uccaccaccg cuccguaaaa guagcaaaag      540

ucgaauacgu acgcaaaaaa cccaaacuaa aagaagucca aguccgccuc gaagaacacc      600

uagaaugcgc augcgcaaca acaucccuaa accccgacua ccgcgaagaa gacaccggcc      660

gaccacgaga auccggcaaa aaacgcaaac gcaaacgccu caaaccaaca uaaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  4625
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt8)

<400>  4625
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaccgaugcu gggcacucuu ccuaucccuc ugcugcuacc      120

uacgccuagu cucagccgaa ggcgacccca uccccgaaga acucuacgaa augcucagcg      180

accacuccau ccgaagcuuc gacgaccuuc aacgccuacu ccacggcgac cccggcgaag      240

aagacggagc cgaacucgac cuaaacauga cccgcuccca cuccggcgga gaacucgaau      300

cacucgcacg cggacgcaga ucccucggcu cccucaccau cgccgaacca gccaugauag      360

cagaaugcaa aacccgaaca gaagucuucg aaaucucacg ccgccucaua gaccgaacca      420

acgccaacuu ccucgucugg cccccaugcg ucgaagucca aagaugcucc ggcugcugca      480

acaaccgcaa cguccaaugc cgcccaaccc aaguccaacu ccgcccaguc caaguacgca      540

aaaucgaaau cguacgcaaa aaaccaaucu ucaaaaaagc caccgucacc cuagaagacc      600

accucgccug caaaugcgaa accguagccg cagcccgacc cguaacacgc ucucccggcg      660

gcagccaaga acaacgagca aaaacacccc aaacacgcgu cacaaucagg accguccgcg      720

uccgcagacc cccaaaaggc aaacaccgca aauucaaaca cacccacgac aaaaccgcac      780

ucaaagaaac ccuaggcgca uaaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  4626
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt8)

<400>  4626
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucccucuucg gccuccuccu ccucaccuca gcccuagcag      120

gccaacgcca aggcacccaa gccgaaucca accucuccuc caaauuccaa uucucaucca      180

acaaagaaca aaacggcgua caagacccgc aacaugaacg cauaaucacc guauccacca      240

acggcagcau ccacucccca agguuccccc auaccuaccc ccgcaacacc guccuagucu      300

ggcgccuugu cgccgucgaa gaaaacgucu ggauccaacu gacauucgac gaacgcuucg      360

gccucgaaga ccccgaagac gacaucugca aauacgauuu cgucgaagua gaagaaccuu      420

ccgauggcac cauccucggc cgcuggugcg gaagcggcac cguccccggc aaacaaaucu      480

caaaaggcaa ccaaauacgc auccgauucg ucuccgacga auacuuccca ucagaacccg      540

gauucugcau acacuacaac aucgucaugc cacaauucac cgaagccguc ucacccuccg      600

uccuaccccc cucagcccuc ccccucgacc uacucaacaa cgccauaaca gccuuuucca      660

cccucgaaga ccucauccga uaccucgaac cagaacgaug gcagcucgac cuagaagacc      720

ucuaccgccc caccuggcaa cucuuaggca aagccuucgu cuucggccgc aaaucgcgcg      780

uaguugaccu uaaccuccua accgaagaag uacgccucua cagcugcacc ccacgcaacu      840

ucuccguauc aauccgcgaa gaacucaaac guaccgacac cauauucugg cccggaugcc      900

uccuagucaa aagaugcggc ggaaacugcg ccugcugccu ccauaacugc aacgaaugcc      960

aaugcguacc cuccaaagua accaaaaaau accacgaagu ccuucaacuc cgcccaaaaa     1020

caggcguacg uggccuccau aaaucacuua ccgacgucgc ccucgaacac cacgaagaau     1080

gugacugcgu cugucgcgga uccaccggag gauaaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  4627
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt8)

<400>  4627
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgccuca ucuucgucua cacccuaauc ugcgccaauu      120

ucugcucaug ccgcgacacc ucugccacac cgcaaagcgc uucaaucaaa gcacuccgga      180

acgccaaccu gcgacgagac gaccucuacc gccgcgacga aaccauccaa gucaaaggaa      240

acggcuacgu acaaagcccc cgauucccaa acuccuaccc ccgcaaccuc cuacucaccu      300

ggagacuaca cucccaagaa aacacccgaa uacaacucgu auucgacaac caauucggac      360

uagaagaagc ugaaaacgac aucugccgau acgacuucgu agaagucgaa gacauaagcg      420

aaacauccac aaucaucaga ggccgcuggu gcggccacaa agaaguacca ccccgcauca      480

aaucccgcac aaaccaaauc aagauaaccu ucaaaucaga cgacuacuuc gucgccaaac      540

ccggauucaa aaucuacuac ucccuccuag aagacuucca acccgccgcc gccuccgaaa      600

caaacuggga aucagucacc ucaagcaucu cagguguauc auacaacucc cccuccguca      660

ccgaccccac acucauagca gacgcccucg acaagaaaau agcugaauuu gacaccgucg      720

aagaccuccu caaauacuuc aaccccgaau ccuggcaaga agaccucgaa aacauguacc      780

uggauacacc acgcuacaga ggccgaucau accacgaccg aaaaaguaaa gucgaccuug      840

accgccucaa cgacgacgcc aaacgcuaua gcugcacccc ucgaaacuac uccgucaaca      900

uccgagaaga acuaaaacuc gcaaacgucg uauucuuccc acguugccuc cuuguccagc      960

gaugcggagg caacugcggc ugcggcaccg ucaacuggcg gagcugcaca ugcaacuccg     1020

gcaaaaccgu aaagaaauac cacgaaguac uccaauucga accaggucac aucaaacguc     1080

gcggcagagc uaaaaccaug gcauuagucg acauacaacu agaccaccac gaacgaugcg     1140

acugcaucug cagcucacga cccccacgcu aaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  4628
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt8)

<400>  4628
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacacacu ccaaauuccc cgccgccggc augucccgac      120

ccuuagacac cuccuuacgc cuaaaaaccu ucuccuccaa auccgaauac caacucguag      180

ucaacgcagu acgcaaacuc caagaauccg gauucuacug gucagccgua accggcggcg      240

aagccaaccu ccuccuaucc gccgaaccag ccggcaccuu ccuaauucgc gacucauccg      300

accaacgcca cuucuucacc cucuccguca aaacccaauc cggcacaaaa aaccuccgca      360

uccaaugcga aggcggauca uucuccuuac aauccgaccc ccgcuccacc caaccagucc      420

cccgauucga cugcguacuc aaacucgucc accacuacau gccacccccc ggcgcccccu      480

ccuucccuuc accccccacc gaacccuccu ccgaaguccc ugaacaaccc ucagcccaac      540

ccuuacccgg cuccccccca cgccgcgcau acuacaucua cucaggcggc gaaaaaaucc      600

cacucguccu cucccgcccc cucuccucca auguagccac acuccaacac cucugccgca      660

aaaccgucaa cggccaccua gacuccuacg aaaaaguaac ccaacucccc ggacccauac      720

gcgaauuccu agaccaauac gacgccccac uauaaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  4629
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt8)

<400>  4629
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guccccuccg ccggccaacu cgcccucuuc gcccucggca      120

uaguacucgc agccugccaa gcccuagaaa acucuaccuc cccccucucc gccgaccccc      180

caguagcagc cgccgucguc ucacacuuca augacugccc agacucccac acccaauucu      240

gcuuccacgg caccugccgc uuccucguac aagaagacaa acccgccugc guaugccauu      300

ccggauaugu cggcgcccgc ugcgaacacg ccgaccuccu agcaguaguc gcagcaucac      360

aaaaaaaaca agcaaucaca gcacuugucg ucgucucaau cgucgcccuc gccguacuaa      420

ucaucaccug cguccucauc cacugcugcc aaguccgaaa acacugcgaa uggugccgag      480

cacucaucug ccgccacgaa aaacccucag cccuacucaa aggccgaacc gcaugcugcc      540

acuccgaaac agucgucuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  4630
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt8)

<400>  4630
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccuccauccg gccuacgacu acuccccuua cuccuacccc      120

uccuauggcu ccuaguccua acacccggcc gccccgcagc cggccuaucg accugcaaaa      180

ccaucgacau ggaacucguc aaacgcaaac gcaucgaagc cauucgagga caaauccuau      240

ccaaacucag acucgccuca ccucccuccc agggcgaagu accacccggc ccccuucccg      300

aagcaguccu cgcccucuac aacucaacaa gagaccgcgu cgccggcgaa uccgccgaac      360

ccgaacccga acccgaagcc gacuacuacg ccaaagaagu uacccgagug cuaauggucg      420

aaacccacaa cgaaaucuac gacaaauuca agcagucaac acacucaaua uacauguucu      480

uuaauaccuc agaacuccgc gaagcaguac cugaacccgu ccuccuaucc cgcgccgaac      540

uccgacuucu cagacucaaa cuuaaggucg aacaacacgu cgaacucuac caaaaauacu      600

ccaauaauuc auggcgcuac cucuccaauc gacuccuugc ccccuccgac ucacccgaau      660

ggcucuccuu cgacgucacc ggagucguac gccaguggcu cucccgcggc ggcgaaaucg      720

aaggcuuccg ccucuccgca cacugcuccu gugacucccg cgacaauacc cuacaagucg      780

acaucaacgg cuucaccacc ggccgacgcg gcgaucucgc caccauccac ggcaugaacc      840

gcccauuccu ccuccuaaug gccacacccc ucgaacgugc ccaacaucug caaucauccc      900

gccaccgacg ugcccucgac accaacuacu gcuucuccuc aaccgagaaa aauugcugcg      960

uacgacaacu auacaucgac uuccgcaaag accucggaug gaaguggauc cacgaaccca     1020

aaggauacca cgccaacuuc ugccucggcc ccugccccua caucuggucc cucgacacac     1080

aauacuccaa aguucucgcc cucuacaacc aacacaaucc cggcgcauca gcagcccccu     1140

gcugcguccc ccaagcccua gaaccccucc caaucgucua cuacgucggc cgaaaaccaa     1200

aagucgaaca auuauccaac augaucgucc gcagcugcaa augcuccuga ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  4631
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt8)

<400>  4631
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uacucuccgc auuccucaua cuccaccucg      120

ucaccgucgc cuuaucuuua uccacaugcu caacccucga cauggaccaa uucaugcgca      180

aacgcaucga agccauccga ggacaaaucu uaucaaaacu caaacuaacc uccccacccg      240

aagacuaccc cgaaccagaa gaagucccac ccgaagucau uuccauuuac aacuccacac      300

gcgaccugcu acaagaaaaa gccucccgcc gcgccgccgc augcgaacgc gaacgcucag      360

acgaagaaua cuacgccaaa gaagucuaca aaaucgacau gccacccuuc uuccccuccg      420

aaaacgccau cccacccacc uucuacagac ccuacuuccg uaucguccgc uuugacguca      480

gcgcaaugga gaaaaacgcc aguaaccuug ucaaagccga guuccgagua uuccgccuac      540

aaaacccaaa agcccgcguc ccagaacaac gcaucgaacu cuaccaaauc cuaaaaucca      600

aagaccuaac uucucccacc caacgauaca uagacucaaa aguugucaag acccgcgcag      660

aaggugaaug gcucagcuuc gacguaacug acgccgucca cgaauggcua caccauaaag      720

accgaaaccu aggcuucaaa auaagccucc acugcccaug cugcacauuc guccccucga      780

acaacuauau caucccgaac aaaucagagg aacuggaagc ccgcuucgcc ggaaucgacg      840

gaaccuccac cuacaccucc ggcgaccaga aaaccauuaa aucaacccgc aaaaagaaca      900

gcggaaaaac cccacaccuc cuacucaugc uacuaccauc cuaccgacua gaaucacaac      960

aaaccaaccg cagaaagaaa cgcgcccucg augccgccua cugcuucagg aacguccaag     1020

acaacugcug ccuacgcccc cuauacaucg acuucaaacg cgaccucgga uggaaaugga     1080

uccacgaacc uaaaggcuac aacgcaaacu ucugcgccgg agcaugcccc uaccucugga     1140

gcuccgacac acaacacucu cgcguccucu cccuauacaa caccaucaac cccgaagccu     1200

ccgccucacc cugcugcguc ucccaagacc ucgaaccccu cacaauacua uacuacaucg     1260

gcaaaacccc caaaaucgaa caacugucca acaugaucgu caaauccugc aaaugcagcu     1320

agggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  4632
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt8)

<400>  4632
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacc uccaacgcgc ccucguaguc cucgcccucc      120

ucaacuucgc cacagucagc cucucccuau caaccugcac cacccuagac uucggccaca      180

ucaaaaagaa aagagucgaa gccauccgcg gccaaauccu cuccaaacuc cgucucacca      240

gcccacccga acccaccguc augacccacg ucccauacca aguccucgcc cuauacaacu      300

ccacgcgcga acuacuagaa gaaaugcacg gagaaagaga agaaggaugc acccaagaaa      360

acacagaauc agaauacuac gcaaaagaaa uccacaaauu cgacaugauc caaggacucg      420

ccgaacacaa cgaacucgcc gugugcccca aaggcaucac cucuaaaguc uuccgauuca      480

acgucuccuc aguagagaaa aaccgcacca accucuucag agccgaguuc cgaguccuca      540

gaguccccaa ccccucuuca aaacgcaacg aacaacgcau ugaacuguuc caaauccuac      600

gaccagacga acacaucgcu aaacaacgau acauaggagg caaaaaccug cccacccgag      660

gaacagcaga auggcucucc uucgacguca ccgacaccgu ccgcgaaugg cucuuacgcc      720

gagaauccaa ccuuggacua gaaaucucca uacacugccc cugccacacc uuccagccca      780

acggagacau acucgaaaac auccacgaag ucauggaaau caaauucaaa ggaguagaua      840

acgaagacga ccacggacgc ggcgaccucg gccgacucaa gaaacaaaaa gaccaccaca      900

acccgcaccu cauacugaug augaucccac cccaucgccu cgauaacccc ggccagggcg      960

gccaacggaa gaaacgagca cucgacacca acuauugcuu cagaaaccuc gaagaaaacu     1020

gcugcgucag accccucuac aucgacuucc gccaagaccu aggcuggaaa uggguacacg     1080

aaccaaaagg cuacuacgcc aacuucugca gcggacccug cccauaccuc cgaucggcag     1140

acaccaccca cucaaccguc cucggccucu acaacacccu uaaccccgaa gcauccgcau     1200

cccccugcug cguaccgcaa gaccuagaac cccucaccau acuauacuac gucggccgaa     1260

ccccaaaagu cgaacaauua uccaacaugg ucgucaaauc cugcaaaugc agcuaaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4633
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt8)

<400>  4633
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaccaguag ccgucugggc cgccuuggcc guuggccuag      120

aacucugggc cgcagcccac gcccugccag cccaagucgc auucaccccu uacgcccccg      180

aacccggcag cacaugccga cuccgcgaau acuacgacca aacggcacag augugcugcu      240

cuaaaugcag cccaggccaa cacgcaaaag ucuucuguac aaaaaccagc gacaccguau      300

gcgacuccug cgaagacucc acuuauaccc aacucuggaa cugggucccc gaaugccucu      360

cuugcggcag ccgcugcuca uccgaucaag ucgaaaccca agccuguacc cgcgaacaaa      420

acagaaucug uaccugcaga cccggcuggu acugcgcccu cuccaaacaa gaaggaugcc      480

gacuaugcgc cccucuccgc aaaugccgcc caggauucgg cguagcacgc cccggcaccg      540

aaaccucaga cgucgucugc aaaccuugug cgcccggaac auucagcaac accaccucau      600

ccaccgacau cugcagaccc caucaaauau gcaacgucgu cgcuaucccc ggaaacgcau      660

caauggacgc ugucugcacc ucaaccucuc ccaccagauc cauggcacca ggggccgucc      720

accuacccca acccgucucc acucgauccc aacacaccca acccacacca gaaccgucca      780

ccgccccauc caccuccuuc cuccucccca ugggcccauc cccgcccgcc gaagguucua      840

ccggagacuu cgcccuuccc gucggccuua ucgucggugu caccgcacuc ggacuccuca      900

ucauaggcgu cgucaacugc gucaucauga cacaaguaaa gaagaaacca cuuugccuac      960

aacgagaagc caaaguaccc caccuccccg cagacaaagc ccguggcacc caaggacccg     1020

agcaacaaca ccuccuaaua accgcccccu cauccuccuc cucaucacuc gaaucauccg     1080

ccucagcacu cgaccgcaga gcgcccaccc gcaaccaacc acaagccccc gguguagaag     1140

ccuccggcgc uggcgaagcc cgcgccucca caggaucuuc cgacucuuca cccggcggcc     1200

acggcaccca agucaacgua accugcauag ucaacguaug cuccuccucc gaccacuccu     1260

cacaaugcag uucccaagca ucaucaacaa ugggagacac agacuccucc cccuccgaau     1320

ccccaaaaga cgaacaaguc ccauuuucaa aagaagaaug ugccuucaga ucccaacucg     1380

aaacaccaga aacccuacuu ggcuccacag aagaaaaacc ccucccccua ggcguucccg     1440

acgcuggcau gaaaccaucc uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  4634
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt8)

<400>  4634
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggucauga gauuguuccc gugcuuucuc cagcuauugg      120

ccggguuagc acuaccggca gugcccccac aacagugggc gcucucggcc gggaacggga      180

gcucggaagu ggaaguggua ccauuccagg aagugugggg gcgcucguac ugucgagcgc      240

ucgagcgauu gguagauguc gugagcgagu acccaagcga gguagagcac auguucucac      300

ccucaugcgu gagcuugcuc aggugcacgg gcuguugcgg ggacgagaac uugcacugug      360

ucccgguaga gaccgcgaac gugaccaugc aacugcucaa gaucagaagc ggggacaggc      420

ccucguacgu ggaauugacc uuuagccagc acgugcgcug ugaaugucgc ccgcucagag      480

aaaagaugaa gcccgagcgc agacgaccga aagggcgcgg gaaaaggcgc agggaaaagc      540

aaaggcccac ggacugucac uugugcgggg acgcgguccc gcgcagguaa ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  4635
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt8)

<400>  4635
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgaccgcc agaccgacac cgcgcccucg ccaucauacc      120

aucucuugcc cggacgcagg agaacagucg augccgcggc aucgcgaggg caaggaccag      180

agcccgcacc aggaggaggg gucgaggggg uaggagcgcg cggaguagcg cucaaacugu      240

ucguacaacu gcuaggcugc aguagguucg ggggagcggu cguacgcgcg ggggaggccg      300

aaccaagcgg cgcggccaga agcgcaagca gcggcaggga agaaccacag cccgaggaag      360

gagaagagga agaggaaaaa gaagaggaaa ggggcccaca guggcgacug ggagcgcgca      420

agcccgggag cuggaccgga gaagcggcag ugugcgcgga cucggccccg gcagcacgcg      480

cgccacaggc ccuggccaga gccucaggca ggggcgggcg cguggccagg cgcggggcag      540

aagaaucagg accgccccac agcccaagca ggcgagggag cgcaaguagg gccgggcccg      600

gccgcgcgag cgaaaccaug aacuuccucc ugagcugggu ccacuggucg cucgcgcuau      660

ugcucuaccu ccaccacgcg aaauggagcc aggccgcgcc cauggcagaa ggaggcgggc      720

agaaccacca cgagguagug aaauucaugg acguauacca aaggagcuac ugccacccca      780

uagaaacgcu uguggacaua uuccaagaau accccgacga aaucgaauac auauucaaac      840

cgagcugcgu cccacucaug cgcugcggag ggugcugcaa cgacgaaggg cucgaaugcg      900

ugcccacgga agagagcaau aucacgaugc aaaucaugcg cauaaaaccg caccaggggc      960

aacacauagg ggagaugucg uuccuacaac acaacaaaug cgaaugccga cccaagaaag     1020

aucgagcacg ccaggaaaag aaaucaguca ggggcaaagg aaagggccag aaaagaaaaa     1080

gaaagaaaag ccgguacaaa agcuggagcg uauacguggg cgcgcgaugc ugccuaaugc     1140

cguggagccu accgggaccg cacccaugcg gacccugcag cgagagaaga aaacaccuau     1200

ucguacagga cccgcagaca ugcaaaugcu cgugcaagaa cacagauucg cgaugcaaag     1260

cacgacagcu cgagcucaau gaaaggacau gcagauguga caaaccccga cgcuagggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4636
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt8)

<400>  4636
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc ucuccugggu ccacuggucc cuagcccucc      120

uacuauaccu ccaccacgcc aaauggagcc aagccgcccc cauggccgag ggcggcggac      180

aaaaccacca cgaagucgua aaauucaugg acguauacca acgaagcuac ugccacccca      240

ucgaaacccu cguagacaua uuccaagaau accccgacga aaucgaauac aucuucaaac      300

caagcugcgu accccuaaug cgaugcggcg gcugcugcaa cgacgaaggc cucgaaugcg      360

uacccaccga agaaagcaac aucacaaugc aaaucaugag aaucaaaccc caccaaggcc      420

aacacauagg cgaaaugucc uuccuccaac acaacaagug cgaaugccgc cccaaaaaag      480

accgcgcccg ccaagaaaag aaauccgucc guggaaaagg caaaggccaa aaacgaaaac      540

gaaaaaaaag ccgcuacaaa uccuggagcg ucuacguagg cgcccgaugc ugccuaaugc      600

cauggucccu ccccggcccc caccccugcg gccccugcuc cgaacgccga aaacaccucu      660

ucguccaaga cccacaaacc ugcaaaugcu ccugcaaaaa cacagacuca cgcugcaaag      720

caagacaacu cgaacuaaac gaacgcaccu gccgcuguga caaaccacga cgauaaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  4637
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt8)

<400>  4637
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaccacuac uccgccgacu acuccucgcc gcccuccucc      120

aacucgcccc cgcccaagcc cccgucagcc aacccgacgc cccaggccac caacgcaaag      180

ucgucuccug gaucgacguu uacacucgcg caacaugcca accccgcgaa guagucgucc      240

cacucaccgu cgaacuaaug ggcaccgucg ccaaacaacu cguccccuca ugcgucaccg      300

uccaacgcug cggaggaugc ugccccgacg acggccuaga augcguccca accggccaac      360

accaaguacg caugcaaaua cucaugaucc gauaccccuc aucccaacua ggcgagaugu      420

cccucgaaga acacucccaa ugcgaaugcc gacccaaaaa aaaagacucc gccgucaaac      480

ccgaccgagc cgccacaccc caccaccgcc cacaaccccg cuccguccca ggcugggacu      540

cagcccccgg cgcaccauca cccgccgaca ucacccaccc cacacccgca cccggccccu      600

ccgcccacgc cgcccccuca accaccuccg cacuaacccc cggccccgcc gccgccgccg      660

ccgacgccgc cgcaucauca guagcaaaag gcggagcaua aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  4638
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt8)

<400>  4638
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuccucg gauucuucuc aguagccugc ucccuucugg      120

ccgcagcccu ccuccccggc ccgcgcgaag cccccgccgc cgccgcagcc uucgaauccg      180

gccuagaccu gagcgacgcc gagcccgacg caggagaagc caccgccuau gccuccaaag      240

accucgaaga acaauugcgc ucggucucgu cagucgacga acucaugacc guccucuacc      300

cagaauacug gaaaauguau aaaugccaac uccgcaaagg uggcuggcaa cacaaccggg      360

aacaagccaa ccucaacagc cgaacagaag aaacaaucaa auucgccgca gcccacuaca      420

acacagaaau ccucaaaucc auagacaacg aauggcgcaa aacccaaugc augccccgcg      480

aagugugcau cgacguaggc aaagaguucg gcgucgccac aaacacauuc uucaaaccac      540

cgugcgucuc cgucuaccgc uguggcggau gcugcaacuc ggaaggacua caaugcauga      600

acacguccac cuccuaccuc uccaaaaccc ucuucgaaau aaccguacca cuaucccagg      660

guccaaaacc cguaacaaua uccuucgcaa accauacuuc cugccgaugc auguccaaac      720

uugacgucua cagacaggua cacagcauaa uccggcguuc ccuacccgcu acccuaccac      780

aaugccaagc agccaauaaa accuguccaa caaacuacau guggaacaac cacaucuguc      840

gcugccucgc ccaagaagac uucauguucu ccucagacgc cggcgacgac ucaacagacg      900

gcuuccacga caucuguggc ccaaacaaag aacuugauga agaaacaugc caaugcgucu      960

gccgagccgg acuccgaccc gcaagcugcg gcccccauaa agaacuagac cggaacucau     1020

gccaaugcgu auguaaaaau aaacuauucc ccucccaaug cggcgccaac cgggaguucg     1080

acgaaaauac cugccaaugc guaugcaaac gcacuugccc acgcaaccaa ccccuaaacc     1140

ccggcaaaug cgccugcgaa ugcaccgaau cgccccaaaa augccuacuc aaaggcaaga     1200

aauuccacca ccaaaccugc uccuguuacc gccgacccug caccaaccgc caaaaagccu     1260

gcgaacccgg uuucucauac ucagaagagg ucugccgaug cguccccagc uauuggaaac     1320

gcccacaaau guccuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  4639
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt8)

<400>  4639
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uaccgugaau gggucgucgu caacguauuc augaugcuau      120

acguucaacu cguccaagga uccucaaaug aacacggccc agucaaacgc agcucccaau      180

ccacacucga acgcuccgaa caacaaaucc gcgccgccuc cucccucgaa gaacuacuuc      240

gcaucaccca uucagaagac uggaaacuau ggcgaugccg ccuccgccuc aaaucauuua      300

ccucaaugga cagccgcuca gccucccacc gcuccacacg cuucgcggcc acuuuuuacg      360

acauagaaac cuuaaaaguc auagaugaag aauggcaacg cacacaaugc ucccccagag      420

aaaccugcgu cgaagucgcc uccgaacucg gcaaaucaac caacaccuuc uucaaacccc      480

caugcgucaa cguauuccgu ugcggaggcu gcugcaacga ggaaucauua aucugcauga      540

acacaagcac auccuacauc uccaaacaac ucuucgaaau cucuguaccc cucaccuccg      600

uccccgaauu aguaccuguc aaagucgcaa accacacagg augcaagugc cucccuaccg      660

caccccgcca ccccuacucc auaauccggc gauccaucca aauccccgaa gaagaccgau      720

gcucacacuc aaagaaacuc ugccccaucg acaugcucug ggacuccaac aaaugcaaau      780

gcguccucca agaagaaaac ccccuagccg gcaccgagga ccacucccac cuacaagaac      840

cagcccucug cggcccccac augauguucg acgaagaccg augcgaaugc gucugcaaaa      900

cccccugccc caaagaccuc auccaacacc ccaaaaacug cuccugcuuc gaaugcaaag      960

aaucccuaga aaccugcugc caaaaacaca aacuauucca cccagauacc ugcucaugcg     1020

aagaccgcug ccccuuccac acacgccccu gcgccuccgg caaaaccgcc ugcgccaaac     1080

acugccgauu ccccaaagaa aaacgcgccg cccaaggacc ccacucccgc aaaaaccccu     1140

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  4640
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt9)

<400>  4640
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg aaaccggcuu cgaacacucc ggccucuggg      120

ucuccguccu cgccggccuc cuccuaggcg ccugccaagc acaccccaua cccgauucuu      180

ccccacuacu ccaauucggc ggccaagucc gccaacgcua ccucuacaca gacgacgccc      240

aacaaacaga agcccaccua gaaauccgag aagacggcac agucggaggc gccgccgacc      300

aaucacccga aucccuccua caacuaaaag cccucaaacc cggcgucauc caaauccucg      360

gcgucaaaac cagccgauuc cucugccaac gccccgacgg cgcccucuac ggaucccuac      420

acuucgaccc agaagccugc uccuuccgcg aacuccuccu agaagacggc uacaacgucu      480

accaaucaga agcccacggc cucccccucc accuccccgg caacaaauca ccacaccgcg      540

acccagcccc acgcggcccc gcccgcuucc uuccccuccc cggccuccca cccgcacucc      600

ccgaaccccc aggcauccuc gcaccccaac ccccagacgu cggcuccuca gacccccucu      660

ccauggucgg ccccucucaa ggcagauccc cauccuacgc cuccuaagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  4641
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt9)

<400>  4641
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuccuucc cuccccuccu acuacuccuc uucuggggcg      120

uugucuccca cuccuucccc gcgacccuag aaacacagga acaagacguu gaccucgucc      180

aaaaauaccu agaaaaauac uacaaccuca aaaacgacgg acgccaagua gaaaaacgac      240

gcaacuccgg ccccgucguc gaaaaacuca aacagaugca agaguucuuc ggccucaagg      300

ucaccggcaa acccgacgcc gaaacacuaa aaguaaugaa acaaccccgc ugcggcguac      360

ccgacgucgc ccaauucgua cucaccgaag guaacccacg cugggaacaa acccaccuca      420

cuuaccggau cgaaaacuac acccccgacc ucccccgcgc cgacgucgac caugccaucg      480

aaaaagccuu ccaacucugg ucaaacguca caccccucac cuucaccaaa gucucugaag      540

gccaagcaga caucaugaua ucauucguac gaggcgacca ccgagacaac ucccccuucg      600

acggcccggg aggcaaccug gcacacgccu uccaaccagg uccaggaauc ggcggcgacg      660

cacacuuuga cgaggacgag cgauggacca acaacuuccg agaauacaac cuccaccgcg      720

ucgcagccca cgagcucggc cacucacugg gacucucaca cuccaccgau aucggagcac      780

ucauguaucc cucuuacacu uucuccggcg acguacaacu agcccaagac gacauagacg      840

gaauccaagc aaucuacgga cgcucccaga accccgucca gcccaucgga ccucaaacac      900

caaaagccug cgacuccaaa cuaacauucg acgccaucac aaccauacga ggcgaaguca      960

uguucuucaa agacagauuc uacaugcgca caaacccuuu cuaucccgaa gucgagcuca     1020

acuucaucuc cgucuucugg ccccaacucc ccaacggccu ugaagcagcc uacgaguucg     1080

ccgaccgcga cgaaguccga uucuucaaag gaaacaaaua cugggccguc caaggccaaa     1140

acguccuaca uggcuacccc aaagacauau acuccuccuu cggcuuccca agaaccguca     1200

aacacaucga cgcagcacuc uccgaggaaa acaccggaaa aaccuacuuc uucgucgcaa     1260

acaaauacug gcgcuacgac gaauacaagc gcucaaugga ccccggcuau ccaaaaauga     1320

ucgcacacga cuuccccggc aucggucaca aagucgaugc uguuuucaug aaagacggcu     1380

ucuucuacuu cuuccacgga acccgccaau acaaauuuga cccaaaaacc aaacgcaucc     1440

ucacacuaca aaaagccaac agcugguuca acugccgcaa aaacuaagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  4642
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt9)

<400>  4642
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuccuucc caccccuacu ccuccuacuc uucuggggcg      120

uagucuccca cucauucgua cucaccgaag gcaacccccg augggaacaa acccaccuca      180

ccuaccgcau agaaaacuac acccccgacc ucccccgcgc cgacguagac cacgccaucg      240

aaaaagccuu ccaacucugg uccaacguaa caccccucac cuucaccaaa gucuccgaag      300

gccaagcaga cauaaugaua ucauucgucc gcggcgacca ccgagacaac ucacccuucg      360

acggccccgg cggcaacuua gcccacgccu uccagcccgg cccaggcaua ggcggagacg      420

cacacuucga ugaagacgaa cgcuggacca acaacuuccg cgaauacaac cuccaccgcg      480

ucgcagccca cgaacucggc cacucccuug gacucucaca cuccaccgac aucggagccc      540

uaauguaccc aucauacaca uucucaggcg acguacaacu cgcccaagac gacaucgacg      600

gcauacaagc aaucuauggc cgcucacaga acccaguaca accaaucggc ccccaaaccc      660

ccaaagccug cgacuccaaa cucaccuucg acgcaauaac cacaauucga ggagaaguca      720

uguucuucaa agaccgauuc uacaugcgca ccaaccccuu cuaccccgaa guagaacuca      780

acuucauauc cgucuucugg ccucaacuac ccaacggccu cgaagcagca uacgaguucg      840

ccgaccgaga cgaaguccga uucuucaaag gcaacaaaua cugggccguc caaggccaaa      900

acguccuaca cggcuaccca aaagacaucu acucuuccuu cggcuuccca cgaacaguaa      960

aacacauaga cgcagcucuc ucagaagaaa acaccggcaa aacuuacuuc uucguagcaa     1020

acaaauacug gcgcuacgac gaauacaaac gcucuaugga ccccggauac cccaaaauga     1080

uagcucacga cuuccccggc auaggucaca aagucgacgc aguauucaug aaagacggcu     1140

ucuucuacuu cuuccacggc acccgccaau acaaauuuga ccccaaaacc aaacgcaucc     1200

ucacccuuca aaaagccaac uccugguuua acugucgcaa aaacuaagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  4643
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt9)

<400>  4643
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaagaaca uccuaaagau acucauggac agcuacagca      120

aagaaucgaa aauccaaacc guucgucgag uaaccuccgu aagccuccua gccguauauc      180

ugaccaugaa cacgagcagc cucguacuag ccaaacccau agaaaacacc aacgauaccu      240

caaucaaaaa cguagaaaaa cugaggaacg cacccaauga agaaaacuca aagaaaguug      300

aagacagcaa aaaugacaag gucgaacacg ucaaaaacau cgaagaagca aaaguagagc      360

aaguagcccc cgagguaaaa agcaaaagca cgcucagauc agcaagcauu gccaacacaa      420

acagcgaaaa auacgacuuc gaauaccuaa acggucuaag cuauaccgaa cugacgaacu      480

uaauaaagaa caucaaaugg aaccaaauaa acggccuauu caacuacucc acaggcagcc      540

aaaaauucuu cggggacaaa aacagaguac aggcaauaau caacgcgcuc caggaauccg      600

gccguaccua cacggcgaac gacaugaagg ggaucgaaac auucaccgaa guacuccgug      660

ccggcuucua ccuuggguau uacaaugacg gacucagcua ccucaacgac cgcaacuuuc      720

aggacaagug cauccccgca augaucgcaa uccaaaagaa cccuaauuuc aaauuaggaa      780

cagccguaca ggacgaggua aucacgagcc ugggcaaauu aaucggcaac gccucugcga      840

acgcagaggu cgucaacaac ugugugccag uccucaagca guuccgggag aaccugaauc      900

aauacgcacc cgacuacgua aagggcacug ccgucaacga acucauaaaa ggcauagagu      960

ucgacuucuc aggcgccgcc uacgaaaaag acguuaaaac gaugcccugg uacggaaaaa     1020

uagaccccuu cauaaacgaa uuaaaagccu uaggccucua cggcaacauc accagcgcaa     1080

cggaaugggc cucagacgua gguaucuacu aucuuuccaa auucggauua uacagcacca     1140

accgcaacga cauaguacaa ucccuagaga aagccgucga uauguacaaa uacggaaaaa     1200

uagcguucgu agccauggaa cgaaucaccu gggacuacga cggcaucggc ucaaacggca     1260

agaaagucga ccacgacaaa uuccuggacg acgccgaaaa acacuaucuc cccaaaaccu     1320

acacauucga caacgggacg uucauaaucc gcgcgggcga caaaguaucc gaagagaaaa     1380

ucaaacgccu auacugggcc uccagagaag uuaaaagcca auuucaccgg guggugggga     1440

acgacaaagc ccuagaaguc ggaaacgccg augacguccu cacaaugaaa aucuucaaua     1500

gucccgaaga auacaaauuc aacaccaaca uaaacggcgu uagcaccgac aaugggggcc     1560

uguacaucga accccggggc acauucuaca ccuacgaaag aacgccucaa caaucuaucu     1620

ucagucugga ggaguuguuc cgccacgaau acacccacua ccuacaagca cguuaccucg     1680

ucgacggccu auggggccag ggacccuuuu acgaaaagaa caggcuaacc ugguucgacg     1740

agggcacagc cgaguucuuc gccgggagca cccgcacauc cggaguacug cccaggaaaa     1800

gcauccucgg cuaccuugcc aaagauaaag uugaccaucg cuacucacug aagaagaccc     1860

uuaacagcgg auaugacgau agcgacugga uguucuacaa cuauggguuc gcgguagcac     1920

acuaccuaua ugaaaaagac augcccacuu ucaucaaaau gaauaaggca auccucaaca     1980

ccgacgucaa auccuacgac gaaaucauua agaaacugag cgacgacgca aacaagaaca     2040

ccgaguacca gaaccacauc caggagcuag ccgacaagua ccagggggca ggaauccccc     2100

uaguaucaga cgacuaccuc aaagaucacg gcuacaagaa agcgagcgaa guauacuccg     2160

aaauaucgaa ggcagcaagc cucacgaaca caagcgugac agccgaaaaa ucacaauacu     2220

ucaacaccuu cacucuccgg gguaccuaca caggcgagac cuccaaggga gaauuuaaag     2280

acugggacga aaugagcaaa aagcucgacg gcacccucga aucacucgcc aaaaacuccu     2340

gguccggcua caagacauua acugcauacu ucacuaauua ccgcgucacc agcgacaaca     2400

aaguccaaua cgacgucguu uuccacgggg uacuaaccga uaacgcagac aucuccaaca     2460

acaaagcacc uaucgcaaaa gucacgggac cauccacugg ggccguugga cgcaauauug     2520

aguucucagg uaaagacagc aaagacgagg acggcaaaau cgucagcuac gacugggauu     2580

ucggagacgg cgcgacauca cgaggcaaaa acagcgucca cgcauauaag aaagccggca     2640

ccuacaacgu uacacuaaag gucacagacg acaaaggagc aacagcgaca gagucauuca     2700

caauagagau caaaaacgag gacacgacga caccuaucac aaaagaaaug gaaccgaacg     2760

acgacaucaa agaagccaac ggcccaauag ucgaaggagu aaccguuaaa ggcgaccuca     2820

acggcucaga ugacgccgau accuucuacu ucgacgucaa ggaagacggg gacguaacaa     2880

uugaacuacc auacucaggg ucaagcaauu ucacauggcu cgucuacaaa gaaggcgacg     2940

aucagaacca uauagcauca ggcauagaca aaaacaacuc gaaagugggc accuuuaaaa     3000

gcacaaaagg ccgccacuac guguucauau acaaacacga cagcgccucg aacaucucuu     3060

acucacuaaa caucaagggc cuaggaaacg agaagcugaa agaaaaagaa aacaacgacu     3120

cuucagauaa ggccaccguc auucccaacu ucaacacaac aaugcaaggc ucgcugcucg     3180

gcgacgacuc cagagacuau uacuccuucg agguaaaaga agaaggagaa gucaacaucg     3240

aauuggacaa gaaagacgag uucgggguga cauggacccu ucacccggaa uccaacauaa     3300

acgacaggau aaccuacggg caaguagaug gaaacaaagu gucgaacaaa gucaagcucc     3360

gacccggcaa auacuacuug cuagucuaca aauacagcgg cucuggcaac uacgaacuac     3420

gaguaaacaa auagggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  4644
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt9)

<400>  4644
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguga cuuucauuuc ccugcuguuc cucuucagca      120

gcgccuacuc caucgcaaac acaaacagcg aaaaauacga cuucgaauac cugaacggac      180

ucaguuacac cgaacucaca aaccucauca agaacaucaa guggaaccaa auaaacggcc      240

ucuucaacua cucgaccggc ucccaaaagu ucuucgggga uaagaaccgc guccaagcca      300

uuaucaacgc ccuccaagaa agcgggcgca cauacaccgc caacgacaug aagggcauag      360

aaacauuuac agaagugcua cgcgcgggcu ucuaccucgg cuauuacaac gacggacuca      420

gcuaccuaaa cgaccgaaac uuccaggaca agugcauacc ggcaaugaua gccauccaga      480

aaaaucccaa cuuuaaacuc ggaacugccg ugcaagacga aguaaucacc ucgcucggaa      540

aacuaaucgg caacgccuca gccaaugccg aaguagucaa uaacugcguc cccgucuuaa      600

agcaauuccg agagaacuug aaccaauacg caccagacua cgucaagggc accgccguaa      660

acgaguuaau caaagggaua gaguucgacu ucucgggagc cgcauaugaa aaagacguca      720

aaaccaugcc augguacggc aaaaucgacc ccuucauaaa cgaacucaaa gcccuuggcc      780

uauacggcaa cauaacaagc gcgacagaau gggccagcga cguaggcauc uacuaccuau      840

caaaguucgg acucuacagc accaaccgga acgacauagu ccaaagccuc gaaaaagcag      900

uagacaugua caaauacggc aaaauagccu ucgucgcaau ggagcgcaua acaugggauu      960

acgacgggau cggcaguaau gguaagaaag uagaccauga caaguuccuc gacgacgcag     1020

aaaaacacua ccuaccuaag acauacaccu ucgacaacgg aaccuucaua auccgcgcag     1080

gcgacaaagu uagugaggag aaaaucaaaa gacuauacug ggcaucaaga gaagucaaau     1140

cacaauucca ccgcguaguc ggcaacgaca aagcccucga aguggggaac gccgacgacg     1200

uccuaacaau gaaaaucuuc aacagccccg aagaauacaa auucaauacu aauauaaacg     1260

gaguaagcac agacaacggc ggccuauaua ucgaaccccg cgggacuuuc uauaccuacg     1320

aaaggacgcc gcaacaaucc auauucucac uagaagaacu auuccgccac gaauacaccc     1380

acuaccucca ggcaagauac cuagucgacg gccuaugggg ucagggccca uucuacgaaa     1440

agaaccgccu aaccugguuc gacgagggaa cagccgaauu uuucgccgga uccacccgca     1500

caagcggagu ccugccccgc aaaucaauac ucggguaccu agcgaaagac aaaguggacc     1560

accgauacag ccuaaagaaa acacucaacu ccggauacga ugacagcgac uggauguucu     1620

acaacuacgg auucgccguc gcacacuacc uauacgagaa agacaugccc acuuucauca     1680

aaaugaacaa agcgauacuc aacaccgacg ucaaaagcua cgacgagauc aucaagaaac     1740

uguccgacga cgcaaauaaa aacaccgaau accagaacca cauucaggaa cucgccgaca     1800

aauaccaagg agccggcauc ccacucguca gcgacgacua ccucaaagac cacggguaca     1860

aaaaggcguc cgaaguauau ucugagauca gcaaagccgc aucccugacc aacacaucag     1920

ucacagcaga gaaaucucag uacuucaaca cauucacgcu ccgggggacc uacacaggcg     1980

aaacuagcaa aggggaguuc aaggacuggg acgagaugag caagaaacug gauggcacac     2040

ucgagagucu cgcgaaaaac uccuggucgg gcuacaaaac gcuuacagca uauuucacca     2100

acuaccgcgu caccucagac aacaaagucc aauacgacgu cguguuccac ggagugcuca     2160

ccgacaacgc cgacaucucc aacaacaagg caccuaucgc aaaggugacc ggccccucaa     2220

caggcgcggu uggacggaac aucgaguucu ccgggaaaga caguaaggac gaggacggca     2280

aaauaguaag cuacgacugg gacuucggag acggggcgac cucccgaggc aagaacagcg     2340

uccacgccua caagaaagcc ggcacauaca acgugacacu uaaaguuacc gacgacaaag     2400

gagccaccgc cacggagucc uuuaccaucg agaucaaaaa cgaagacacc acaaccccaa     2460

uaaccaaaga aauggaaccu aacgacgaca uuaaggaggc aaacggccca auaguagaag     2520

gaguuacggu caagggugac cucaacgguu ccgaugacgc agacaccuuc uacuucgacg     2580

ucaaagaaga cggggaugua accaucgaac uacccuacuc cggauccuca aauuucacuu     2640

ggcuaguaua caaggagggc gacgaccaaa accacauagc cucggggaua gacaaaaaca     2700

acucuaaagu aggaaccuuu aaguccacaa agggacggca cuacgucuuu aucuacaagc     2760

acgacuccgc uuccaacaua ucguacucgu uaaacaucaa aggacuagga aacgaaaaac     2820

ucaaagagaa agaaaacaac gacucaucgg acaaagcgac aguaauacca aacuucaaca     2880

ccacgaugca gggcucccua uugggagaug acagccgaga cuacuacucg uuugaaguaa     2940

aagaggaagg cgaagucaac aucgaacuag auaagaaaga cgaguucgga guuacgugga     3000

cccuccaccc cgagagcaac aucaaugacc gaauuaccua uggccagguc gacgguaaca     3060

aaguaucuaa uaaagucaaa cuccgcccag gcaaauacua ccuccucguc uacaaguaca     3120

gcgguagcgg caacuacgaa cuacgcguga auaaauaagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  4645
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt9)

<400>  4645
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga cauucaucuc ccuacuguuc uuauuuaguu      120

ccgccuauag uaugaaaaag aacauucuca aaauccucau ggacagcuac agcaaagaga      180

gcaagaucca gaccgugcgu cgaguaacca gcgucagcuu acuagcggua uaccuaacca      240

ugaacacauc cagccuaguc cuggcaaaac ccaucgaaaa caccaaugac acuuccauca      300

agaacgucga gaagcuacga aacgcaccaa acgaagagaa uagcaagaaa guugaagauu      360

ccaaaaauga caaaguagag cacgucaaaa acaucgaaga agcaaaaguc gaacaaguag      420

ccccggaagu caaauccaag agcacgcucc gcuccgccag uagacggcgc aggaaacgca      480

ucgcaaacac aaacuccgag aaauacgacu ucgaauacuu gaacggauua agcuacacgg      540

agcuaaccaa ccucaucaaa aauauaaaau ggaaccaaau aaacggccua uucaacuaua      600

gcaccggguc ccagaaauuc uucggagaua agaaccgcgu acaagcuauc aucaaugccc      660

ugcaggaauc cggccgcaca uacacggcca acgacaugaa agguauagaa acauucacag      720

aagugcuaag ggccggcuuc uaccucggcu acuacaacga cgggcuauca uaccuaaaug      780

acagaaauuu ucaggacaaa ugcauaccgg cuaugaucgc gauacagaaa aacccgaacu      840

ucaagcuagg cacggccgua caagacgaag ucaucaccuc cuugggaaaa cucauaggca      900

acgccuccgc gaacgccgaa gucgucaaca acuguguacc cguccuaaaa caguuuagag      960

agaaccuaaa ccaguacgcu ccggacuacg ucaaagggac agcagugaau gaacugauua     1020

agggaauaga guucgacuuc ucaggcgcug ccuacgaaaa ggacgugaaa accaugcccu     1080

gguacggcaa gaucgaccca uucaucaacg aauuaaaagc acucggccua uauggcaaca     1140

uaaccuccgc caccgaaugg gcaucggacg ucggaauaua cuaccucagu aaauuuggac     1200

uguauagcac caacagaaac gacaucgucc aaagccucga gaaagcaguc gacauguaca     1260

aauacggcaa aauagccuuc guggcaaugg aaaggaucac augggacuac gacggcaucg     1320

gguccaacgg aaagaaagua gaccacgaca aauuucuuga cgacgccgag aaacacuacc     1380

uaccaaaaac uuacaccuuc gacaacggca ccuucauaau cagagcagga gacaaaguca     1440

gcgaagagaa aaucaaacgg cuuuacuggg ccucacguga agugaaaagc caguuccacc     1500

gcgucguggg aaaugacaag gcauuggaag uagggaacgc ggacgacguc cuaacaauga     1560

aaauauucaa cagcccagaa gaauacaaau ucaacacuaa cauaaaugga gucuccaccg     1620

acaacggcgg ccucuacaua gaaccaaggg gcaccuuuua cacauacgaa cgcacaccuc     1680

agcaaagcau auuuucacua gaagaacucu uccgucacga auacacccac uaccuccagg     1740

cuagauaccu cguugacgga cuguggggcc agggccccuu uuaugagaaa aaccgccuca     1800

cgugguucga cgaaggcaca gccgaguucu ucgccggcag cacacgaacc agcggcguac     1860

uaccacgaaa aucgauccuc ggcuaccugg caaaagacaa agucgaucau agguacagcc     1920

ucaaaaagac acuaaacagc ggauaugacg acucugacug gauguuuuac aacuacgggu     1980

ucgccgucgc acacuaccuc uacgaaaagg acaugcccac auucaucaaa augaacaagg     2040

cgauccuaaa cacugacgua aaaagcuacg acgaaauaau aaagaagcua agcgacgaug     2100

ccaacaagaa cacagaguac caaaaccaca uucaggaacu ugccgacaaa uaccagggag     2160

ccggaauccc gcucguaucc gacgacuacc uaaaagacca cggauacaaa aaggcauccg     2220

aagucuacag cgaaauaagc aaggccgcgu cacuaacaaa cacgucaguc accgcagaga     2280

aaucccaaua cuucaacacc uuuacacuga gagggacaua caccggcgaa accucaaaag     2340

gagaguucaa agacugggac gaaaugucca agaaacuaga cggaacacuc gaaucgcuag     2400

cuaaaaacuc cuggagcgga uacaaaaccc ucacggcuua uuucaccaac uaccgcguca     2460

cgagcgacaa caagguacaa uaugacguug ucuuccacgg cguccucacg gacaacgccg     2520

acaucucaaa caauaaggcc cccauagcaa aaguaacagg accauccacc ggcgcagucg     2580

gccgaaacau agaguucuca ggcaaagauu ccaaagacga agacgggaaa aucguuaguu     2640

acgauuggga cuucggcgac ggcgccaccu cgcgagguaa gaacuccgug cacgcauaca     2700

aaaaggccgg aaccuacaac guuacccuaa aggugacaga cgacaaagga gcgacggcga     2760

cagaaucuuu cacaaucgaa aucaaaaacg aagacacuac aacacccauc acgaaagaaa     2820

uggagcccaa cgacgacauc aaggaagcaa acgggccgau cguugaagga guaaccguca     2880

aaggagaccu caacgggagc gacgacgcag acaccuucua cuucgauguc aaagaggacg     2940

gggacguaac aaucgagcuc cccuacucag gaagcagcaa cuucacaugg cuaguguaca     3000

aggagggcga cgaccagaac cacauagcgu ccggcaucga caaaaacaac ucaaaaguag     3060

gcaccuucaa aaguaccaaa ggccgccacu acguuuucau cuacaagcac gacuccgccu     3120

ccaacauaag cuacucgcua aacaucaagg gcuuaggcaa cgaaaaacug aaagaaaaag     3180

aaaacaacga cucaucugac aaggccaccg uaauacccaa uuucaacaca accaugcagg     3240

gcucacugcu cggagacgac ucacgagauu acuacuccuu ugaaguaaaa gaagaaggcg     3300

aaguaaacau cgaauuggau aagaaagacg aguucggcgu gacguggaca cuucacccag     3360

aaucaaacau caacgacagg auaaccuaug ggcaaguaga cggcaacaaa guaucuaaca     3420

aggucaagcu ccgccccggc aaguacuacc ugcucgucua caaauacagc ggaucuggaa     3480

acuaugaacu ccgcguaaac aaauaaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  4646
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt9)

<400>  4646
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuca aaaucauacu gaaccgcgga aaaaccauga      120

agagaaagug ccuauccaaa agguuaaugc ucgccauaac cauggccacg auauucacag      180

ugaacucgac ccucccgauu uacgccgccg uagacaaaaa caacgcgacc gccgcgguac      240

agaacgaguc caaacgguac acgguauccu aucucaagac ccucaacuac uacgacuugg      300

ucgaccuucu cgucaaaaca gagauagaaa accuucccga ucuauuccaa uacucuagcg      360

acgccaaaga guucuacgga aacaaaacaa gaaugucguu caucauggac gagaucggcc      420

gccgcgcucc ucaauacaca gaaauagacc acaaaggcau acccacccug gucgaggucg      480

uccgcgccgg cuucuaccua gguuuccaca acaaagaacu aaacgaaauc aacaagcgca      540

gcuucaaaga aagggucaua cccuccauac uggcuaucca gaaaaacccc aacuucaaau      600

ugggaaccga aguacaagac aaaauagucu cagccacagg ccugcucgca gguaacgaga      660

cugcaccacc ggaaguggua aauaacuuca ccccgauacu ccaagacugu aucaagaaca      720

ucgaccguua cgcccucgac gaucucaaaa gcaaagcacu cuucaacgug cucgcagcac      780

caacguauga uaucacugaa uaccugagag caaccaaaga aaaaccggag aacacccccu      840

gguacgggaa aaucgacggg uucauaaacg aauugaagaa acuggcccuu uacggcaaaa      900

uaaacgacaa uaacucaugg auaaucgaca acggaaucua ccacauagca ccccucggca      960

aacuccacag uaacaacaaa auagggaucg agacccuaac cgaagugaug aagguuuacc     1020

ccuaucucuc aaugcagcau cuccagagug cagaccaaau aaaaaggcau uacgacucaa     1080

aagacgccga gggcaacaag auaccucucg acaaguucaa gaaagagggc aaagaaaagu     1140

acugccccaa aaccuacacg uuugacgaug guaaagucau cauaaaggca ggagcacgag     1200

ucgaagaaga aaaagucaaa cgucuuuacu gggccagcaa ggaaguaaac agccaguucu     1260

uccgagucua cggcaucgac aaaccacucg aggaaggcaa cccggaugac auccucacaa     1320

uggugaucua caacagcccg gaggaguaca aacuuaacuc cgucuuguac ggcuaugaca     1380

ccaacaaugg cgggauguac aucgaaccag aaggaacuuu cuucaccuau gagcgcgaag     1440

cccaagaguc caccuauacc cucgaggaac ucuuccgaca cgaauacacu cauuacuuac     1500

aaggccgcua cgcaguaccc gggcaauggg gccgcaccaa gcuauacgac aaugacagac     1560

uaacuuggua cgaggaaggc ggagccgaac uauucgcagg cuccacacgc accucaggaa     1620

uacucccucg caaaagcaua guauccaaca uacacaacac cacccgaaac aacagauaua     1680

aacuaagcga caccguccac agcaaauacg gagcgagcuu cgaguucuac aacuacgccu     1740

gcauguuuau ggacuauaug uacaacaaag auaugggcau acucaacaaa cuuaacgacc     1800

uagcaaagaa caacgacguc gacggcuacg acaacuacau acgggaccuc agcucgaacu     1860

augcacuaaa cgacaaauac caagaccaca ugcaggaacg cauagacaac uacgaaaacc     1920

ucaccguacc cuucgucgca gacgacuacc uaguccgaca cgcguacaaa aaucccaacg     1980

aaaucuacuc cgaaaucagc gaagucgcca agcugaagga ugccaaaagc gaagugaaga     2040

aaucacaaua uuucucaacc uucacgcucc gcggcucaua cacagguggc gccuccaaag     2100

gaaaacuaga ggaucaaaaa gcaaugaaca aguucauaga cgacucccuc aaaaagcucg     2160

acacauacuc cugguccggc uacaaaacac uuaccgcgua cuucaccaac uacaaaguag     2220

acuccucgaa ucgaguaacc uacgacgucg uauuccacgg cuaccuucca aacgaaggcg     2280

acuccaaaaa cucccuaccc uacggaaaga uaaacggcac cuacaaaggu accgaaaagg     2340

agaaaaucaa auucuccagc gaagggucau uugacccaga cggaaaaauc gucuccuacg     2400

aaugggacuu cggagacgga aauaagucaa acgaagaaaa ccccgaacac agcuacgaca     2460

aagugggaac cuacaccgua aagcucaaag ugacagauga caaaggcgaa ucaaguguaa     2520

guacgaccac ugcugagaua aaagacuugu cggagaauaa acuucccgua aucuacaugc     2580

acguccccaa aucaggagca cuaaaccaga aagucguauu cuacggcaaa ggaaccuacg     2640

accccgacgg cucaauagcc ggauaucaau gggauuucgg ggacggaagc gacuuuucgu     2700

cggaacagaa ccccagccac guguacacga agaaagggga auacaccguc acccugcggg     2760

uaauggacag cucaggccaa auguccgaga aaacaaugaa aauaaaaauc accgaccccg     2820

ucuaccccau cggcacggaa aaagaaccca acaacuccaa agaaaccgca uccggcccaa     2880

ucgugcccgg cauacccguc uccggcacaa uagaaaauac cuccgaccaa gacuacuucu     2940

auuucgaugu caucaccccc ggagagguca aaaucgacau caacaaacug ggcuacggcg     3000

gagcaaccug gguagucuac gacgagaaca acaacgccgu caguuacgca accgacgacg     3060

ggcaaaaccu cagcggaaag uucaaagccg acaaaccagg aagauacuac auccaccuau     3120

acauguucaa uggcagcuac augcccuaca gaauuaauau cgagggaucc gugggccgcu     3180

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  4647
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt9)

<400>  4647
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacgaaaau gccuuagcaa acgccugaug cucgccauua      120

ccauggcgac aauauucacc gugaacagua cgcucccuau cuacgcagcc guagacaaaa      180

acaacgcaac cgcagccgua cagaacgagu ccaaacgcua caccgucucc uaucucaaga      240

cccuaaacua cuacgaccuu guagaccucc ucgugaagac cgaaaucgaa aaccuacccg      300

accucuucca auacuccagc gacgccaagg aguucuacgg aaacaaaacc cgaaugagcu      360

ucauaaugga cgaaaucggu cgccgcgcgc cccaauacac ggaaaucgac cauaaaggaa      420

ucccuaccuu agucgagguc guaagagcgg guuucuaccu aggauuccac aacaaagagc      480

uaaacgagau caacaaacgc uccuucaaag aacgcgugau ccccucuauc cuagccaucc      540

agaaaaaccc aaauuucaaa cucggcaccg aaguacaaga uaaaauagua agcgccaccg      600

gacuccucgc uggcaacgaa accgcacccc cagaaguagu gaauaacuuc acacccaucc      660

uccaagauug caucaaaaau auagaccgau acgcccugga cgauuuaaaa agcaaagcac      720

ucuucaacgu acucgcugca cccacauacg acaucacaga guacuugagg gcaacgaaag      780

agaaacccga aaacaccccc ugguacggaa aaauagacgg cuucaucaac gaacuaaaga      840

aauuggcgcu auaugggaaa aucaacgaca acaacaguug gauaaucgac aacggcaucu      900

aucacauagc accccucggc aaacuccaua gcaacaacaa aauaggcaua gaaacacuaa      960

cugaagucau gaaaguauac cccuaucuca gcaugcaaca ccuacaaucc gccgaccaaa     1020

ucaaacgcca cuacgacagc aaagacgcag aaggcaacaa aauaccccuc gacaaguuca     1080

agaaagaagg aaaagagaaa uacugcccca aaaccuacac cuucgacgac ggcaaaguaa     1140

ucaucaaggc cggagcacga guagaagaag agaaaguaaa acgacucuac ugggcgagca     1200

aagaagucaa uagccaauuc uuccgcguuu acgguaucga uaaaccgcuu gaagaaggca     1260

acccagauga cauccuaacg augguuaucu auaacagucc cgaagaauac aaacucaaca     1320

gcguccuuua uggguacgac accaauaacg gcgggaugua caucgaaccc gaggggaccu     1380

ucuucacaua cgaacgagaa gcccaagaau ccaccuacac acuagaagaa cucuuccgcc     1440

acgaauacac ccacuaucuu cagggcagau acgccguacc aggacaaugg gggaggacca     1500

aauuauacga caacgaccga cucacauggu acgaagaagg cggcgccgag uuauucgcug     1560

gaaguacucg aaccuccggc auccuucccc gaaaaagcau agucucgaac auccacaaca     1620

caacccguaa caaucgcuac aaacuauccg auacagucca cagcaaauau ggagcuagcu     1680

uugaguucua caacuaugcc ugcauguuca uggacuacau guacaacaag gacaugggca     1740

uccucaacaa acuaaacgac cuggcgaaaa acaacgacgu agacggcuac gacaacuaca     1800

uacgcgaucu uagcucuaac uacgcccuaa acgacaaaua ucaagaccau augcaggaac     1860

ggaucgauaa uuacgaaaau cucacaguac ccuucgucgc cgacgacuac cuaguccggc     1920

augcauacaa aaacccgaau gagauauacu ccgagaucuc agaagucgca aaacugaaag     1980

acgcaaaguc ggaaguuaaa aagagccaau acuucagcac auucacccuc cgcggaucuu     2040

acaccggcgg ggccuccaag gggaaacuug aggaccaaaa agcaaugaac aaauuuaucg     2100

acgacagccu caaaaagcuc gacaccuaca gcuggagcgg guacaaaaca cuuacggcau     2160

acuucaccaa uuacaaaguc gacucgagca aucgggucac cuacgacgug gucuuccacg     2220

gcuaccuacc gaacgaaggc gacagcaaaa acucacuacc guacggcaaa auaaacggca     2280

cguauaaagg gaccgaaaaa gaaaagauca aguucucauc agaaggcucc uucgacccag     2340

acggaaaaau agugagcuau gagugggauu ucggcgacgg gaacaaauca aacgaagaga     2400

acccggagca cagcuacgac aaagucggga ccuacaccgu caaacuaaaa gucaccgaug     2460

acaaaggcga guccucagua uccacgacca cggcugaaau caaagaccug agcgaaaaca     2520

agcucccagu cauauacaug cacgucccga aauccggcgc ccuaaaccag aaagucgucu     2580

ucuacggcaa aggcacuuac gacccagacg gcagcauagc aggauaccaa ugggacuucg     2640

gggacggcuc cgacuucuca ucagaacaga acccaucaca cgucuacacc aaaaagggcg     2700

aguacacagu uacacuccgc gugauggacu ccuccggaca aaugagcgag aaaacaauga     2760

aaauaaaaau aaccgacccg guauacccaa uaggcacgga aaaggaaccu aacaacagca     2820

aagaaacagc aucagguccc auuguacccg gcaucccagu cucaggaacc aucgaaaaca     2880

ccuccgacca agacuacuuc uacuucgaug uaauaacacc cggcgaagua aaaaucgaca     2940

ucaacaaacu cggguacggg ggagcaaccu gggucguaua cgaugaaaac aacaacgcug     3000

ucucauacgc aaccgacgac ggacagaacc ugagcggcaa guucaaagcc gacaaaccag     3060

ggagguacua cauacaccuc uacauguuca augguagcua caugccuuac cguauaaaua     3120

ucgaaggauc uguaggacga uaaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  4648
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt9)

<400>  4648
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguga ccuucauaag ccuucucuuc cucuucucau      120

ccgccuacag cguacaaaac gagucgaaaa gauacaccgu aucauaccuc aagacccuca      180

acuacuacga ucucgucgau cuauuaguca agacagaaau cgaaaaucua cccgaccuau      240

uccaguacuc aucggacgcc aaagaguucu acggcaacaa aacacgaaug agcuucauua      300

uggacgaaau agguagacga gcgccgcagu acacggaaau cgaccacaaa gggaucccca      360

ccuuagucga aguuguacgc gcgggcuucu accuaggauu ucacaacaaa gaacuuaacg      420

aaaucaacaa acgcaguuuc aaagaacgcg ucauccccag cauccuagcg auccagaaaa      480

accccaauuu uaaacucggc accgaaguac aggacaagau agugucagca acaggccugc      540

ucgccggaaa cgaaacggcc ccacccgaag uagucaauaa cuucacaccc auacugcagg      600

acugcaucaa aaauaucgac cgauacgcac ucgacgaccu caagagcaaa gcccucuuca      660

acgugcucgc cgccccaacc uacgacauaa ccgaauacuu gagggccaca aaagaaaaac      720

ccgaaaacac cccaugguac ggcaaaauug acggauucau caacgagcug aagaaacucg      780

cccucuacgg gaaaaucaau gacaacaaca gcuggaucau cgacaacggc aucuaccaca      840

uugccccgcu aggcaaacua cacuccaaca acaaaaucgg caucgaaacg cucacggaag      900

ucaugaaagu auauccauau cuauccaugc aacaccucca aucugccgac caaaucaaac      960

gccacuacga cagcaaggac gcggaaggaa acaaaauccc acucgacaag uuuaagaagg     1020

aaggcaaaga aaaauacugc ccuaaaaccu acacguucga ugacgggaaa guaauuauca     1080

aagccggcgc ccgagucgaa gaggaaaagg ugaaacgccu auacugggcc uccaaagagg     1140

uuaauucaca auuuuuccga gucuauggca ucgacaaacc acucgaggaa gguaaccccg     1200

acgauauccu caccauggua auauauaauu cgcccgagga auauaaacuc aacagcgucu     1260

uauacggcua cgacaccaac aacgguggca uguacaucga gccggaaggc accuucuuca     1320

ccuacgagcg ugaagcccaa gaauccacgu acacacuuga ggaacuauuc cgacaugaau     1380

acacccacua ccugcaaggc cgguacgcag uaccuggcca guggggccgc acuaaacucu     1440

acgacaacga ccgucucacc ugguacgaag aagguggagc cgaacucuuc gccggcucca     1500

cccgcaccag cggcauccua ccccgaaaau ccauagucuc gaacauucac aacacaaccc     1560

gaaauaaccg cuacaaacuc agcgacaccg uacacucaaa auacggagcc agcuucgagu     1620

ucuacaacua cgcgugcaug uucauggacu acauguacaa caaagauaug gggauucuaa     1680

acaaacuuaa cgaccucgcc aaaaauaacg acgucgacgg uuacgacaac uauauacgag     1740

aucuuucauc gaacuacgca cuaaacgaca aauaccagga ccacaugcaa gaacgcaucg     1800

acaacuacga aaaccucacc guccccuucg ucgcagacga uuaccucguc cgacacgcau     1860

acaagaaccc caacgaaaua uacucggaga ucagcgaagu cgccaagcuc aaagaugcaa     1920

aauccgaagu caaaaaguca caguacuuua gcacauucac acuccgcggg agcuacaccg     1980

gcggcgcguc caagggaaag cucgaagacc aaaaagccau gaacaaauuu auagacgacu     2040

cccucaagaa acucgacacc uacucgugga gcggcuacaa aacacuuacc gcauacuuca     2100

ccaacuacaa aguagacagc ucaaaucggg uaacuuacga cguagucuuc cacggcuacc     2160

uucccaauga aggagacagc aagaacucac ucccuuacgg caaaauaaau ggaacguaca     2220

agggcacgga aaaggagaaa aucaaauuca gcuccgaagg cuccuucgac cccgacggaa     2280

aaauaguauc auacgaaugg gacuucggcg acggcaacaa gaguaacgaa gaaaaucccg     2340

aacacucaua cgacaaaguc ggcacguaca ccgucaaacu aaaaguaaca gacgacaaag     2400

gcgaauccuc agugaguacg accaccgcag aaaucaaaga cuuaucagaa aacaaacucc     2460

ccguaauaua caugcacguc ccaaagagcg gggcacucaa ccaaaaaguc gucuucuacg     2520

gcaaaggaac cuacgacccu gacggaucca ucgccggcua ccagugggau uucggcgacg     2580

gaagcgacuu cucaucggag caaaacccaa gccacgucua cacgaaaaag ggagaauaca     2640

cagugacacu ccgaguaaug gacuccucag ggcagauguc cgagaaaacc augaaaauaa     2700

agaucaccga cccugucuac cccaucggaa ccgaaaagga gccuaacaau uccaaagaaa     2760

ccgccagcgg accaauagua cccgguaucc ccgucuccgg aaccaucgaa aacacgucag     2820

accaggacua cuucuacuuc gacgucauaa ccccgggcga aguaaaaauc gacaucaaca     2880

aacuaggcua cggcggagcc acaugggucg uauacgacga aaacaacaac gcgguaucuu     2940

acgcaacaga cgacggccaa aaccuaagcg gcaaguucaa agcagacaaa cccgggcgcu     3000

acuacaucca ccuguacaug uucaacggaa gcuacaugcc auacagaaua aauaucgaag     3060

gcuccguagg acguuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4649
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt9)

<400>  4649
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguca ccuucaucuc ucuacuguuc cucuucucua      120

gcgcauauag caugaaacgg aaaugucuau ccaaacgccu gaugcuggcc auuacgaugg      180

ccaccaucuu caccgucaac ucuacccugc cgaucuacgc cgccguagac aagaacaacg      240

ccaccgccgc ucgccgccga agaaagaggg uccaaaacga aagcaaaaga uacacaguaa      300

gcuaccuuaa gacacucaac uacuacgacc ucguagaccu acucgucaag acagaaauug      360

agaaccuccc cgaccuauuc caauacagca gcgacgccaa agaguucuac ggcaacaaaa      420

cccgaauguc uuucauaaug gaugaaauag gacgcagagc gccccaauac acggaaaucg      480

aucacaaagg cauacccacc cuaguggaag ucguacgagc uggcuucuau cuggguuucc      540

acaacaaaga acugaacgaa auaaacaagc gcagcuucaa agaacgcgug auccccucaa      600

uacuggcuau ccagaaaaau cccaauuuca aacuagggac cgaaguccaa gacaagaucg      660

uguccgcgac aggacuccuc gccggcaacg aaaccgcccc gccggaaguc guuaacaacu      720

ucacgccaau acuacaagac ugcauuaaaa acaucgaccg auacgcccua gacgaucuga      780

aauccaaggc acuauucaac guucuggccg caccaacaua cgacaucaca gaguaccugc      840

gugccacaaa agaaaaacca gaaaauaccc ccugguacgg caaaaucgac ggauucauua      900

augaguugaa aaagcuagca cucuacggaa aaaucaacga caauaacagc uggaucaucg      960

acaacggcau uuaccacaua gcgccccucg gcaaacugca cuccaacaac aaaaucggua     1020

uagagacacu cacagaggug augaaaguuu acccauaccu aagcaugcaa caccuucaau     1080

ccgccgacca aaucaaacgc cacuacgacu ccaaagacgc ggaaggcaac aaaauacccc     1140

ucgacaaauu uaaaaaggag ggcaaagaaa aauacugccc aaagaccuac accuucgaug     1200

acggcaaagu aauaaucaaa gcaggagcca gagucgagga ggagaagguc aaaaggcuau     1260

acugggcauc uaaggaagug aacagccaau ucuuucgggu auacggaauc gacaagcccc     1320

uagaagaagg uaaccccgac gacauccuua caaugguaau auacaacagc ccggaagagu     1380

acaaacucaa caguguucua uacggauacg auacgaacaa cggaggcaug uacaucgaac     1440

cggagggcac cuucuucacc uacgagcgag aggcccaaga aagcacauac accuuagaag     1500

aacuguuccg acacgaauac acccauuacc uccaaggcag auacgcuguc cccggccaau     1560

ggggacgcac uaaacuauac gauaacgacc gccuaacaug guacgaagag gguggcgccg     1620

aacucuucgc cggcucaacg agaacgagcg gaauccugcc gcgcaaaagc aucgucagca     1680

acauacacaa cacaacgcga aacaaucguu acaaacucuc ggacacgguc cacucaaaau     1740

acggcgcguc auucgaguuc uacaacuacg ccugcauguu cauggauuac auguacaaua     1800

aggacauggg cauccuaaac aaacucaacg accucgcuaa aaacaacgac gucgacggcu     1860

acgacaacua uauccgagac cuaagcucga acuacgcacu caaugacaaa uaccaagacc     1920

acaugcaaga gcgcaucgac aacuacgaaa accuaacagu acccuucguu gcggacgacu     1980

aucucgucag gcacgcauac aagaacccaa acgagauaua cagcgaaauc agcgagguag     2040

ccaaacuuaa ggacgccaaa uccgaaguca agaaaucgca guacuucuca accuucacgc     2100

uacguggcag cuacaccggg ggagcaagca aaggaaaacu cgaggaccaa aaagcaauga     2160

acaaguuuau ugacgacagc cuaaagaaac uagauacaua uuccuggucc ggcuacaaaa     2220

cgcuaacggc auacuucacg aacuacaagg uugacucaag uaaccgcgua acauacgacg     2280

uaguuuucca cggauaccua ccaaaugaag gcgacuccaa aaacucgcug ccauacggaa     2340

aaaucaaugg cacauacaaa gggacagaga aggagaaaau caaauucagu ucagaaggau     2400

ccuucgaccc agacggcaaa aucguuucau augaauggga uuucggagac gggaacaaau     2460

caaacgaaga aaacccugag cacagcuacg acaaagucgg cacauauaca guaaagcuca     2520

aagucacgga cgacaagggc gagagcagcg uaagcacgac caccgcagaa aucaaggacc     2580

ucuccgaaaa uaaacuccca gucauauaca ugcacguacc aaaaucgggc gcccucaacc     2640

agaaaguagu guucuacgga aaaggcacau acgauccgga cggauccaua gcaggcuacc     2700

aaugggauuu cggagauggg agcgacuucu cgagcgaaca aaacccguca cacgucuaca     2760

cuaaaaaggg cgaguacacc guaacccuuc ggguaaugga cuccuccgga caaaugucug     2820

agaaaaccau gaaaaucaag auaaccgacc caguauaccc caucggcacc gaaaaagaac     2880

caaacaacuc caaagaaacu gccuccggcc ccaucguacc gggaauccca gucuccggca     2940

ccaucgaaaa caccagcgac caagauuacu ucuacuucga cguaaucacc cccggagaag     3000

ucaaaaucga caucaacaaa cugggcuacg gaggagcuac cuggguaguc uacgacgaaa     3060

acaacaacgc cgucaguuac gccaccgacg acgggcaaaa ccuguccggu aaauuuaagg     3120

ccgacaagcc agggcgauac uacauccacc uguauauguu uaacggaucc uauaugcccu     3180

accgaauaaa uaucgaagga aguguaggcc gcuaaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  4650
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt9)

<400>  4650
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacucuucgc augccuccuc ggcgcagccu      120

ucgccaugcc ccucccuccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacacc ccucaaaugg uaucaaucca ucagaccacc cuaccccucc uacggcuacg      240

aacccauggg cggcuggcuc caccaccaaa ucauccccgu ccucucacaa caacacccuc      300

ccacccacac ccuccaaccc caccaccaca uccccguagu ccccgcccaa caacccguca      360

ucccccaaca acccaugaug cccguccccg gccaacacuc aaugaccccc auccaacacc      420

accaacccaa ccucccacca cccgcccaac aacccuacca accccaaccc guccaacccc      480

aaccccacca acccaugcaa ccccaaccac ccguacaccc caugcaaccc cucccacccc      540

aaccaccccu accucccaug uuccccaugc aaccccuccc acccaugcuc cccgaccuca      600

cccucgaagc cuggcccucc accgacaaaa ccaaacgcga agaaguagac uaaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  4651
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt9)

<400>  4651
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuacccc cccacccagg ccaccccggc uacauaaacu      120

ucuccuacga aguacucaca ccccuaaaau gguaccaauc cauccgaccc cccuaccccu      180

cauacggcua cgaacccaug ggcggcuggu aaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  4652
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt9)

<400>  4652
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacauaaacu      120

ucucauacga aguccucacc ccccuaaaau gguaccaauc cauccgcccc ccccccaugc      180

uccccgaccu cacacucgaa gccuggcccu caaccgacaa aacaaaacgc gaagaagucg      240

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  4653
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt9)

<400>  4653
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccguaaugg ccccccgaac ccucguccuc cuacucucag      120

gagcccucgc ccucacccaa accugggcca ugccccuccc accccaccca ggccaccccg      180

gauacaucaa cuucuccuac gaaguacuca ccccccuaaa augguaccaa uccauccgcc      240

cccccuaccc cucauacggc uacgaaccca ugggcggaug guaaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  4654
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt9)

<400>  4654
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccguaaugg caccccgcac ccucguccua cuccuauccg      120

gcgcccucgc ccucacacaa accugggcca ugccccuccc accccacccc ggccaccccg      180

gcuacauaaa cuucuccuac gaaguccuca ccccacucaa augguaccaa uccauccgcc      240

caccacccau gcuacccgac cucacacucg aagccuggcc cuccaccgac aaaacaaaac      300

gcgaagaagu cgacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  4655
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt9)

<400>  4655
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuaguc ggcgccgccu      120

ucgccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccuaacacc ccuaaaaugg uaccaaucca ugauccgccc acccuacucc uccuacggcu      240

acgaacccau gggcggaugg cuccaccacc aaaucauccc cgucgucucc caacaacacc      300

cccucaccca cacccuccaa ucacaccacc acauccccgu aguccccgcc caacaacccc      360

gcguacgaca acaagcccuc augcccgucc ccggccaaca auccaugacc cccacccaac      420

accaccaacc caaccuccca cuccccgcac aacaacccuu ccaaccccaa cccguccaac      480

cccaacccca ccaaccaaug caaccccaac cacccgucca acccaugcaa ccccucuuac      540

cccaaccacc ccuaccaccc auguuccccc uccgcccccu accacccauc cuccccgacc      600

uccaccucga agccuggccc gccaccgaca aaacaaaaca agaagaaguc gacuaaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  4656
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt9)

<400>  4656
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuaccac cccacccagg ccaccccggc uacaucaacu      120

ucucauacga aguccucacc ccccuaaaau gguaccaauc aaugauccgc cccccauacu      180

cauccuacgg cuacgaaccc augggcggcu gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4657
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt9)

<400>  4657
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccacccagg ccaccccggc uacaucaacu      120

ucuccuacga aguacucacc ccccuaaaau gguaccaauc caugauccgc ccccccccca      180

uacuccccga ccuccaccuc gaagccuggc ccgccacaga caaaaccaaa caagaagaag      240

uagacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4658
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt9)

<400>  4658
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagucaugg caccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccuaacccaa accugggcaa ugccacuacc cccacacccc ggccaccccg      180

gcuacaucaa cuucucauac gaaguccuaa caccccucaa augguaccaa ucaaugaucc      240

gcccacccua cuccuccuac ggcuacgaac ccaugggcgg cugguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4659
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt9)

<400>  4659
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg caccccgaac acucguccuc cuccucuccg      120

gcgcccucgc ccucacacaa acaugggcca ugccccuccc accccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca caccccuaaa augguaccaa uccaugaucc      240

gcccaccccc aauacucccc gaccuacacc ucgaagccug gcccgccacc gacaaaacca      300

aacaagaaga agucgacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4660
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt9)

<400>  4660
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uacucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuaccaccc caccccggac accccggcua caucaacuuc uccuacgaag      180

uccuaacacc ccucaaaugg uaccaaaaua ugauacgcca ccccuacaca uccuacggcu      240

acgaacccau gggcggaugg cuccaccacc aaaucauccc cgucgucuca caacaaaccc      300

cacaauccca cgcccuccaa ccccaccacc acauccccau gguccccgcc caacaacccg      360

gcauccccca acaacccaug augccccucc ccggccaaca cuccaugacc cccacccaac      420

accaccaacc caaccuaccc cuacccgccc aacaacccuu ccaaccccaa cccguacaac      480

cccaacccca ccaaccccuu caaccccaau cucccaugca ccccauccaa ccccuccucc      540

cccaaccacc ccuuccaccc auguucucaa ugcaaucacu ccuccccgac cucccccucg      600

aagccuggcc cgccaccgac aaaaccaaac gagaagaagu cgacuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4661
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt9)

<400>  4661
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuaccac cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccuaaca ccccuaaaau gguaccaaaa caugauccgc cacccauaca      180

ccucauacgg cuacgaacca augggcggcu gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4662
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt9)

<400>  4662
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccucccac cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccuaaca ccccucaaau gguaccaaaa caugauccga caccccuccc      180

uacuccccga ccucccccua gaagcauggc ccgccaccga caaaaccaaa cgcgaagaag      240

ucgacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4663
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt9)

<400>  4663
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg caccccgcac ccuaguccuc cuccucucag      120

gcgcccucgc acucacccaa acaugggcca ugccccuacc cccacacccc ggccacccag      180

gcuacaucaa cuucucauac gaaguccuca ccccacuaaa augguaccaa aacaugauac      240

gccaccccua caccucauac ggauacgaac ccaugggcgg cugguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4664
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt9)

<400>  4664
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg caccccgcac ucucguccuc cuacucuccg      120

gcgcccuagc ccucacccaa accugggcca ugccccuacc cccacacccc ggccaccccg      180

gcuacaucaa cuucucauac gaaguccuca ccccacuaaa augguaccaa aacaugaucc      240

gccaucccuc acuccucccc gaccuccccc uagaagccug gcccgccaca gacaaaacca      300

aacgcgaaga agucgacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4665
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt9)

<400>  4665
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uacucuucgc cugccuccuc ggcgcagccu      120

ucuccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc ucuuacaucc      180

gccaccccua caccuccuac ggcuacgaac ccaugggcgg cuggcuacac caccaaauca      240

uccccgucgu aucccaacaa accccacaau cacacgcucu ccaaccccac caccacaucc      300

ccaugguccc cgcccaacaa cccggcaucc cccaacaacc caugaugccc cuccccggcc      360

aacacuccau gacccccacc caacaccacc aacccaaccu cccccuccca gcccaacaac      420

ccuuccaacc ccaacccguc caaccccaac cacaccaacc acuacaacca caauccccca      480

ugcaccccau ccaaccacuc cucccccaac caccccuccc acccauguuc ucaaugcaau      540

cccuccuacc cgaccuuccc cuugaagccu ggcccgccac cgacaaaacc aaacgagaag      600

aagucgacua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  4666
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt9)

<400>  4666
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuucgc augccuccua ggcgccuccc      120

ucgccaugcc ccucccaccc caccccggac accccggcua caucaacuuc uccuacgaag      180

uccucacccc acuaaaaugg uaccaaaaca ugauccgcca ccccuacacc uccuacggau      240

acgaacccau gggaggcugg cuccaccacc aaaucauccc cgucgucuca caacaaacac      300

cccaauccca cgcacuccaa ccccaccacc acauccccau gguccccgcc caacaacccg      360

gaauccccca acaacccaug augccccucc ccggacaaca cuccaugacc cccacccaac      420

accaccaacc aaaccucccc cuccccgccc aacaacccuu ccaaccacaa cccguccaac      480

cccaacccca ccaaccacuc caaccccaau cccccaugca ccccauccaa ccacuccucc      540

cccaaccacc ccucccaccc auguucucaa ugcaaucccu ccuucccgac cucccccucg      600

aagccuggcc cgccaccgac aaaaccaaac gcgaagaagu agauuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4667
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt9)

<400>  4667
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uacucuucgc cugccuacuc ggcgccgcau      120

ucucaaugcc ccuccccccc caccccggcc accccggcua cauaaacuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaaaca ugauuagaca cccaucccuc cuccccgacc      240

ucccccucga agcauggccc gcaaccgaca aaaccaaacg cgaagaaguc gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  4668
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt9)

<400>  4668
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcacaugga uccucuucgc cugccuacuc ggagccgcuu      120

uuuccaugcc ccucccuccc caccccggcc accccggcua cauaaacuuc uccuacgaag      180

accucuaccu cgaagccauc cgcaucgacc gcaccgccuu cguccucaca ccccuuaaau      240

gguaccaaaa caugauccgc caccccuaca ccuccuacgg cuacgaaccc augggcgguu      300

ggcuccacca ccaaaucauc cccguagucu cacaacaaac cccacaaucc cacgcccucc      360

aaccccacca ccacauacca augguccccg cccaacaacc aggcaucccc caacaaccca      420

ugaugccccu ccccggccaa cacuccauga ccccaaccca acaccaccaa cccaaccucc      480

cccuccccgc ccaacaaccc uuccaacccc aacccgucca accccaaccc caccaacccc      540

uccaacccca aucccccaug caccccaucc aaccucuccu cccccaaccc ccacucccac      600

caauguucuc aaugcaauca cuccuccccg acuuaccccu agaagccugg cccgccaccg      660

acaaaaccaa acgagaagaa guagacuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  4669
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt9)

<400>  4669
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc ucauaugaag      180

uccucacacc ccucaaaugg uaccaaaaca ugauccgcca ccccacaccc caaucccacg      240

cccuccaacc acaccaccac auccccaugg uccccgccca acaaccaggc aucccacaac      300

aacccaugau gccccuacca ggccaacacu ccaugacccc cacccaacac caccaaccca      360

accuaccccu ccccgcacaa caacccuucc aaccacaacc cguccaaccc caaccccacc      420

aaccccuaca accccaaucc cccaugcacc caauccaacc ccuccucccc caaccacccc      480

ucccacccau guucuccaug caaucacucc uccccgaccu cccccuagaa gccuggcccg      540

caaccgacaa aaccaaacgc gaagaagucg acuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  4670
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt9)

<400>  4670
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccucccac cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguacucacc ccucucaaau gguaccaaaa caugauccga caccccuaca      180

ccuccuacgg cuacgaaccc augggcggcu ggcuccacca ccaaaucauc cccgucgucu      240

cccaacaaac accccaaucc cacgcacuac aaccccacca ccacaucccc augguccccg      300

cccaacaacc cggcaucccc caacaaccca ugaugccacu ccccggccaa cacuccauga      360

cccccaccca acaccaccaa cccaaccucc cccuacccgc ccaacaaccc uuccaacccc      420

aacccgucca accacaaccu caccaaccac uccaacccca aucacccaug caccccaucc      480

aaccacuccu accccaaccc ccacucccac ccauguucuc caugcaauca cuccuccccg      540

accucccccu agaagccugg cccgccaccg acaaaaccaa acgcgaagaa gucgacuaag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  4671
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt9)

<400>  4671
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaggagucg cccggcuacc ccuacuccua ggacuccucc      120

uacuaccacg cccuggacga ccccuagacc uggccgacua cacguacgac cuagccgaag      180

aagacgacuc cgaaccccuc aacuacaaag accccugcaa ggccgccgcc uuccuaggcg      240

acauagcccu agacgaagaa gaccuccgag ccuuccaagu ccaacaagcg gucgaccugc      300

gccgacacac ggccaggaaa ucauccauaa aagccgcugu accgggaaac acaucaaccc      360

ccucaugcca aucgacaaac ggacaaccac aaaggggcgc augcggaaga uggcgcgggc      420

gaucacgcuc acgccgcgca gccacaagcc gcccggagcg aguguggccc gacgggguaa      480

uacccuucgu cauaggggga aacuucacug gaucacaacg ggcagucuuu agacaagcaa      540

ugagacacug ggaaaagcau accugcguca cauuccuaga acggaccgac gaagauucau      600

acaucguauu caccuaccgc ccaugcggau guugcucaua cguaggccga agaggcggcg      660

gcccccaagc gauaucgaua ggcaagaacu gcgacaaauu cgggauaguu guacacgaac      720

uaggacacgu cguaggcuuc uggcacgaac acaccagacc cgaccgggac cggcacguau      780

ccauaguccg cgaaaacauc caacccggac aagaauacaa cuuccuaaaa auggaaccac      840

aagaagucga aucgcuaggc gaaaccuaug acuucgauuc caucaugcac uaugcucgca      900

acaccuucuc acgaggcauc uuccucgaca ccaucguccc caaauacgaa guuaacggag      960

ucaaaccacc cauaggacaa cgcacgcgac ucucaaaagg cgauaucgcu caagcacgca     1020

aacucuacaa gugucccgcc ugcggcgaaa cgcuccagga cucgacaggc aacuucucau     1080

cccccgaaua cccgaacgga uacagcgcac acaugcacug ugucuggcga aucucaguaa     1140

caccaggcga gaaaaucauc cuuaacuuca caucccucga ccuguacaga ucccgccucu     1200

gcugguacga uuacgucgaa gucagagacg gguucuggcg aaaagcaccg cuccgaggcc     1260

gauucugugg auccaaacug ccagaaccca uagucuccac agacucucga cucuggguug     1320

aguucagaag cucuaguaac ugggucggca aaggcuucuu cgccgucuac gaagcaaucu     1380

gcggaggaga cguaaagaaa gauuacggcc acauacaguc ccccaacuac cccgacgacu     1440

accggcccag uaaaguaugu aucuggagaa uccagguaag cgaaggcuuc cauguugggc     1500

ucaccuuuca gagcuucgaa auagaacgcc acgacucaug cgcuuaugac uaucucgaag     1560

uacgcgacgg ccacuccgaa ucaagcacac ucauaggcag auacugcgga uacgaaaaac     1620

ccgaugacau caaauccacg uccagccgcc uauggcucaa auucgucuca gauggaagca     1680

uaaacaaagc cggauuugcu guuaacuucu ucaaggaagu agacgagugc ucccgaccca     1740

accgcggcgg gugcgaacaa cgcugccuca acacacucgg uuccuacaaa ugcagcugcg     1800

acccaggcua cgaacuagcc ccugauaagc gucgcugcga agcagccugc gguggguucc     1860

ucacaaaacu aaacggaucc auaacaagcc cuggcuggcc aaaagaauau cccccuaaca     1920

agaacugcau cuggcaacug guggcgccca cacaauaccg aauaagccua caauuugacu     1980

ucuucgagac agaaggaaau gacgugugca aguacgacuu cguagaaguc cgcuccgggu     2040

uaaccgccga cuccaagcug caugggaaau ucugcggauc cgaaaaacca gaagugauua     2100

cgagccaaua caacaacaug cgagucgagu ucaagucaga caacacaguc uccaagaaag     2160

gcuuuaaagc ucacuucuuc ucagacaaag acgagugcuc aaaagacaau ggaggguguc     2220

aacaagacug cguuaacaca uucggguccu acgaaugcca augccgcucu ggguucguac     2280

uucacgauaa caagcacgac ugcaaagaag ccggaugcga ccacaaggug acaagcaccu     2340

ccggcaccau aacguccccc aacuggccag auaaauaccc cucaaagaaa gaaugcacgu     2400

gggccaucag uagcacuccc ggccacagag ucaaacucac auucauggaa auggacaucg     2460

aaagccagcc ggagugcgcg uacgaccacc ucgaaguguu cgacggacgc gacgcgaagg     2520

cuccagugcu cggccgauuc ugcggaucca agaagccaga accagucuua gcaacuggaa     2580

gccgaauguu ccuacgauuc uacuccgaca auuccguuca acgaaaaggc uuccaagccu     2640

cccacgccac cgaaugcggc ggacaagucc gagcggacgu aaaaaccaaa gaccucuaca     2700

gccacgcgca auucggggac aacaacuacc cagguggcgu agacugcgaa uggguaauag     2760

ucgcagaaga aggcuacgga gucgagcuag uauuccagac cuucgaaguu gaagaagaaa     2820

cagacugcgg cuacgacuac auggaacuau ucgacgguua cgacuccacc gcaccccggc     2880

ucggacggua cugcggcucc ggcccaccag aagaaguaua cucagcagga gacagcgucc     2940

ucgucaaauu ccacuccgau gauaccauaa caaagaaagg guuucaccua cgcuacacga     3000

gcaccaaauu ccaagacacu cuacacagcc gcaaauaagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  4672
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt9)

<400>  4672
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guagccggca cccgaugccu acucgcccuc cuucuccccc      120

aaguccuccu aggcggcgcc gccggccugg ucccagaacu aggccgccgc aaauucgcag      180

ccgcauccuc cggacgccca ucaucacagc ccuccgacga aguccucucc gaguucgaac      240

ucagacuacu aucgauguuc ggccuuaaac aacgccccac cccaucccgu gacgccguag      300

ucccaccaua caugcucgac cuauaccgcc gccacuccgg gcaacccgga ucaccagcac      360

ccgaccaccg ccucgaacgc gccgcauccc gcgccaacac aguccgcucc uuccaccacg      420

aagaaucccu cgaagaacuc cccgaaacau caggcaaaac aacccgccga uucuucuuca      480

accucuccuc cauacccaca gaagaguuca ucaccuccgc agaauuacaa gucuuccgcg      540

aacaaaugca agacgcacuc ggcaacaacu ccuccuucca ccacagaauc aacaucuacg      600

aaaucaucaa acccgcaacc gccaacagca aauucccagu aacccgacuc cuugacacac      660

gacucgucaa ccaaaacgcc uccagauggg aaucauucga cgucacacca gcagucaugc      720

gcuggaccgc ccaaggccac gcaaaccaug gauucguggu agaagucgcc caccuagaag      780

aaaaacaagg agucuccaaa cgccacgucc gcaucucacg cucccuccac caagacgaac      840

acucaugguc acaaauccga ccccuccuag uaacauucgg acacgacggc aaaggccacc      900

cccuacauaa acgcgaaaaa cgacaagcca aacauaagca acgaaaacgc cucaaaucaa      960

gcuguaaacg ucauccacuc uacgucgacu ucucugacgu cggcuggaac gacuggaucg     1020

uagcaccacc cggcuaccac gccuuuuacu gccacggaga augccccuuc ccccucgccg     1080

accaccuaaa uuccaccaac cacgcaauag uccaaacccu aguuaacucc gucaacucca     1140

aaaucccaaa agcaugcugc guucccacag aacucucagc aaucuccaug cucuaccuug     1200

acgaaaacga aaaagucguc cugaaaaacu accaagacau ggucgucgaa ggcugcggcu     1260

gccgauaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  4673
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt9)

<400>  4673
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auacccggca accguaugcu cauggucguc cuccucugcc      120

aaguacuccu cggcggagcc ucacacgcau cucucauacc cgaaacuggc aaaaaaaaag      180

ucgccgaaau ccaaggccac gcaggaggac gccgcucagg ucaaucccac gaacuccuac      240

gcgacuucga agccacccua cuacaaaugu ucggccuccg acgccgaccc cagcccucca      300

aauccgccgu cauacccgac uacaugcgcg accucuaccg acuucaaucc ggcgaagaag      360

aagaagaaca aauacacagc accggccucg aauaccccga acguccagcc ucccgcgcca      420

acaccguccg cucuuuccac cacgaagaac accucgaaaa cauccccggc acauccgaaa      480

acuccgccuu ccgauuccuc uucaaccuau ccucaauccc cgaaaacgaa gucauauccu      540

ccgccgaacu ccgucucuuc cgcgaacaag uagaccaagg ccccgauugg gaacgcggcu      600

uccaccgcau caauaucuac gaagucauga aaccaccagc cgaagucgua cccggacacc      660

ucaucacacg cuuacuagac acccgccucg uccaccacaa cguaacacgc ugggaaaccu      720

ucgacgucuc cccagcuguu cuccgaugga cacgcgaaaa acaacccaac uacggccucg      780

ccaucgaagu cacccaccuc caccaaaccc gaacccacca aggccaacac gucagaaucu      840

cccgcucucu cccccaaggc ucaggcaacu gggcccaacu acgcccccua cuugucaccu      900

ucggccacga cggacgaggc cacgcacuaa cgcgacgccg ccgcgccaaa cgcucaccca      960

aacaccacuc ucagcgcgcc agaaaaaaaa acaaaaauug ccgccgacac ucacuguacg     1020

ucgacuucag cgacgucggc uggaaugacu ggaucgucgc cccccccggc uaccaagcau     1080

ucuacugcca cggcgacugc ccauucccac uagcugacca ccucaacucg accaaccacg     1140

caauuguaca aacccucguc aauuccguca acagcuccau cccaaaagca ugcugcgugc     1200

ccaccgaacu cuccgcuauc uccaugcucu accucgacga auacgacaaa gucguacuca     1260

aaaacuacca agaaaugguc gucgaaggau gcggcugccg cuaaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  4674
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt9)

<400>  4674
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggucuag gccgccgcgc acaguggcuc ugcugguggu      120

ggggacuacu cugcuccugc ugcggcccuc cccccuuacg uccacccuua ccagcagccg      180

ccgccgcggc agcaggaggc caacuacucg gcgacggugg cucccccgga cgaacggaac      240

aacccccccc cucaccccaa uccucaagcg gcuuccucua ccgccgccuc aaaacccaag      300

aaaaacgaga aaugcaaaaa gaaauacuau ccguccuagg ccuuccacac cggccccgcc      360

cacuccacgg ccugcaacaa ccccagccac ccgcccuccg ccaacaagaa gaacaacaac      420

aacaacaaca acucccccgg ggugaacccc cuccaggccg ccuaaaaucu gccccucucu      480

ucaugcucga ccucuacaau gcccuauccg ccgauaacga cgaagaugga gcgucagaag      540

gagaacgcca acaaucaugg ccccacgaag ccgccuccuc aucccaacgc cgacaacccc      600

cgcccggcgc cgcccacccc cuaaaccgua aaucccugcu cgcccccggc ucaggcagcg      660

guggugcauc cccacucacc ucggcccaag acuccgcauu ccuaaacgac gcagacaugg      720

ucaugagcuu cgucaaccua gucgaauacg acaaagaauu cuccccacgc caacgacacc      780

auaaagaauu caaauucaac cucucacaga uacccgaagg agaagucguc accgccgcag      840

aauuccgaau cuacaaagac ugcguaaugg guagcuucaa aaaccaaaca uuccuaaucu      900

cuauauacca aguacuccaa gaacaccaac accgugacag ugaccuauuc cuccucgaca      960

cccgagucgu uugggccuca gaagaaggcu ggcucgaauu cgacaucaca gcaaccagca     1020

accuaugggu aguaacaccg caacacaaca ugggccuaca acuauccgua gucacccgag     1080

acggaguaca cguucacccg cgcgcagccg gccucguagg acgcgacggc cccuacgaca     1140

aacagcccuu cauggucgcc uucuucaaag ucuccgaagu acacguccgc accacccgcu     1200

ccgccuccuc ucgacgccgc caacaauccc gaaaccgauc cacccaaucc caagacgucg     1260

cccgcguuuc cucugccuca gacuacaauu ccucagaacu caaaaccgcc ugccgaaaac     1320

acgaacuaua uguaucauuc caagaccuug gcuggcaaga cuggaucauc gcccccaaag     1380

gcuacgcagc caacuacugc gacggcgaau gcuccuuccc acuaaacgcc cacaugaacg     1440

ccaccaacca cgccaucguc caaacacucg ugcaccuuau gaaccccgaa uacguaccca     1500

aaccaugcug cgcccccacc aaacuaaacg ccaucuccgu acucuacuuc gaugacaacu     1560

ccaacgucau acuaaaaaaa uaccguaaca ugguaguacg cgccugcggu ugccacugag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  4675
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt9)

<400>  4675
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugcguu cacuacgagc agccgcccca cacucauucg      120

ucgcccucug ggcuccccuu uuucuccuac gcucugcccu cgccgacuuc ucccuagaca      180

acgaaguaca cagcucauuc auccaccgcc gucuccgcuc ucaagaaaga cgcgaaaugc      240

aacgugaaau ccucuccauc cucggccucc cccaccgacc ccgcccccac cuacaaggca      300

aacacaacuc cgcccccaug uucaugcucg accucuacaa cgccauggcc guagaagaag      360

gaggaggacc cgguggccaa ggcuucuccu accccuacaa agccgucuuu uccacccaag      420

gucccccgcu cgcaucacuc caagacuccc acuuccucac cgacgccgac auggucaugu      480

cauucgucaa ccuugucgaa cacgacaaag aguucuucca cccccgcuac caccaucgcg      540

aguuccgcuu cgaccucagc aaaauucccg aaggcgaagc cgucaccgcc gccgaguucc      600

gaaucuacaa agacuacauc cgugaacgcu ucgacaacga aacuuuccgc aucucagucu      660

accaaguccu ccaagaacac cuaggccgcg aaucagaccu cuuucuccuc gacucacgaa      720

cccucugggc cucagaagaa ggauggcucg ucuucgacau cacagccaca uccaaccacu      780

gggucgucaa cccucgccac aaccuuggac uccaacuguc cgucgaaacc cucgacggcc      840

aauccauaaa ccccaaacuc gccggccuca uaggccgaca cggaccccaa aacaaacaac      900

cauucauggu cgcauuuuuc aaagcaaccg aaguccacuu uagauccauc cguuccaccg      960

gaucaaaaca acgcucccaa aaccgcucca aaacccccaa aaaccaagaa gcccuccgca     1020

uggccaacgu agcagaaaac uccuccagcg accaacgcca agccugcaaa aagcacgaac     1080

ucuacguauc auuucgagac cucggcuggc aagacuggau aaucgcccca gaaggcuacg     1140

ccgcauacua cugcgaagga gaaugcgccu ucccccuaaa uuccuacaug aacgccacca     1200

accacgccau cguccaaacc cucguccacu ucaucaaccc cgaaacuguc ccaaaacccu     1260

gcugcgcccc cacacaacua aacgccaucu caguccucua cuuugacgac ucaucuaacg     1320

uaauccuaaa gaaauaucgc aacaugguag uccgcgccug cgguugccac uagggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  4676
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt9)

<400>  4676
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagccuccg ccgcccuccu augccuccuc cucaccgccg      120

ccgcauucuc cccccaaggc cucgcccaac cagucggcau aaacaccucc accaccugcu      180

gcuaccgauu caucaacaaa aaaaucccaa aacaacgacu cgaauccuac cgccgcacca      240

ccuccuccca cugcccccga gaagccguca ucuucaaaac caaacucgac aaagaaaucu      300

gcgccgaccc aacccaaaaa uggguccaag acuucaugaa acaccuagac aaaaaaaccc      360

aaaccccaaa acucuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  4677
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt9)

<400>  4677
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cucuuaaccc uuaucauacu ucuucccguc gucagcaagu      120

ucagcuuugu cucacucagu gcaccccaac acuggagcug ccccgaagga acacuugccg      180

gcaacggcaa uagcacaugc guugggccgg cucccuuccu aauauucagc cacggaaaca      240

gcauauuccg aaucgacaca gagggaacca acuacgaaca gcugguaguc gacgcuggcg      300

uaagcgucau cauggacuuc cacuacaacg agaagcgaau cuacugggua gaucucgaac      360

gccaacuacu gcaacgggua uucuugaacg gcucgcgaca ggagcgcguc ugcaauaucg      420

aaaagaacgu cucaggaaug gcuaucaacu ggauuaauga agaggugaua uggagcaacc      480

aacaggaggg aaucauaacc gucacagaca ugaaggguaa caacucccac auccuucuca      540

gcgcgcucaa auacccugca aaugucgccg uggauccugu cgaacguuuu auauucuggu      600

caagugaagu agccggcucc cucuacagag ccgaccucga cgguguaggg gucaaggcac      660

uacucgaaac guccgagaaa auaacagcag uaucgcugga cguacucgac aaacgccuau      720

ucuggauuca guacaaccga gaaggcagca acuccuuaau cugcaguugc gacuacgacg      780

gagguagcgu gcauauaagu aaacacccaa cgcagcacaa ccuauuugcc augucacugu      840

ucggggaccg caucuucuac agcaccugga aaaugaaaac aauauggauc gcaaacaaac      900

acaccggcaa ggauaugguc cgcaucaacc uacacucuuc auucguaccc cuaggggagc      960

ucaaaguagu gcacccucuc gcccaaccaa aagcagagga ugauaccugg gaacccgaac     1020

aaaagcugug caaacuccga aagggcaacu gcucgagcac cgucugcgga caagaccugc     1080

aaagccaccu cugcaugugu gcggaaggau acgcacucuc acgagaccgg aaguacugcg     1140

aggacgucaa cgaaugcgcc uucuggaacc acggaugcac ucuuggaugu aagaacaccc     1200

caggauccua uuacuguacc ugcccagucg gauucguacu acuaccagac ggaaaacgau     1260

gccaccaacu gguauccugc ccccgaaacg uauccgaaug cucccacgau ugcguccuaa     1320

ccucagaggg gccccucugc uucugcccag agggauccgu guuagaacgc gacggcaaga     1380

cuugcagcgg cugcagcagc ccagacaacg gcgggugcag ccaacuaugc guaccacuau     1440

caccaguuuc augggaaugc gacugcuucc cggguuacga ccuccagcuc gacgaaaaau     1500

caugugcggc cagcggacca cagcccuucc uccuauucgc caauucacaa gacauccggc     1560

acaugcacuu cgacggcacc gacuacggua cccuacugag ccaacaaaug gguauggugu     1620

acgcgcucga ccacgaccca guagaaaaca aaauauacuu cgcccacaca gcccucaagu     1680

ggaucgaacg agccaacaug gauggaucac aacgcgagcg gcuaauagag gaaggugugg     1740

acgugccaga aggccuggcc guagacugga uaggccgcag auucuauugg acagacagag     1800

guaaaucacu caucggacga ucagaccuca acggcaaaag guccaaaauc aucacuaaag     1860

agaacauauc acaaccacgc ggcauagccg uccaccccau ggccaaacgc cucuucugga     1920

ccgacacggg caucaaccca agaauagagu ccagcagccu ccagggccua ggaagacuug     1980

uaaucgcauc guccgaucuc auuuggccca gcgggaucac aaucgauuuc cuaacugaca     2040

aacucuacug gugcgacgcc aaacaaagug uaaucgaaau ggcaaaccuc gacggaucga     2100

aacgacggcg ccucacccaa aacgauguug gccaucccuu cgcaguagca gucuuugagg     2160

acuacgucug guucagcgac ugggccaugc ccuccguaau gcggguuaac aaacgcaccg     2220

gcaaagaccg aguccgacua caggguucca ugcuuaaacc gagcucccua guuguaguac     2280

acccacuagc aaaacccggg gccgaccccu gcuuauauca aaacggagga ugcgaacaca     2340

ucugcaagaa acgccucggc accgcauggu guagcugccg agaaggauuu augaaagccu     2400

ccgacggcaa aaccugucug gcccuagaug gccaccaacu ccuugcgggc ggcgaaguag     2460

accuuaaaaa ccaagugacc ccgcuagaca uacucucaaa aacgcgcguc ucagaagaca     2520

acaucacaga aagccaacac augcucguag cagaaaucau gguaagcgac caagacgacu     2580

gcgcacccgu aggaugcagc auguaugcac ggugcauaag cgaaggagaa gacgcgaccu     2640

gccaaugccu aaaaggauuc gccggagacg guaagcucug cucagauauu gacgaaugcg     2700

aaaugggagu acccgugugu ccacccgcca gcucaaagug caucaacacu gaaggaggcu     2760

acgucugcag augcagcgag ggcuaucaag gcgacggcau ccauugccua gauauagacg     2820

agugccagcu aggcgagcac ucgugcggcg agaacgcguc gugcacaaac acggaaggug     2880

gcuauacaug caugugcgcc ggaagacuca gcgaaccggg ucuaauuugc cccgacagca     2940

ccccaccucc acaccuucgc gaagacgacc accacuacuc cguccgcaac ucggacucag     3000

aaugcccccu cagucaugau ggcuacugcu ugcaugacgg cguuuguaug uauaucgaag     3060

cccuagacaa guacgcaugc aacugcgucg uagguuacau cggagagcgc ugccaauauc     3120

gcgaccuaaa auggugggaa cucagacacg caggucacgg ucagcaacaa aagguuaucg     3180

ucguagccgu uugugucgug guccuaguca ugcuccuucu ccuaucgcuc uggggcgccc     3240

acuacuacag aacccaaaaa cuccuaucca aaaacccgaa aaaucccuac gaagaaucga     3300

guagggacgu acguucgcga cgacccgcag acacggaaga cggcaugagu ucgugccccc     3360

aaccaugguu cguaguuauu aaggaacauc aagauuugaa aaacggcgga cagccagucg     3420

ccggagagga cggccaagca gcagauggau ccaugcaacc cacaucaugg agacaagaac     3480

cccaacuaug cggaauggga acggaacaag gcugcuggau uccagucagu uccgacaaag     3540

gcucaugccc acaaguaaug gaacgaucgu uccacaugcc auccuacgga acccaaacac     3600

ucgaaggcgg uguagaaaag ccacacagcc uccucucggc aaacccccua uggcagcagc     3660

gcgcacuaga cccuccccau caaauggagc ugacccaaua gggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  4678
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt9)

<400>  4678
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggca gacgcaugga aaugcuaugc gccggccgag      120

uccccgcacu ccuacucugc cucggcuucc accuccuaca agccguccua uccaccacag      180

ucaucccauc augcauccca ggcgaaagcu cugacaacug caccgcccua guccaaaccg      240

aagacaaccc ccgcgucgcc caagucucca ucacaaaaug cucauccgac augaacggcu      300

acugccuaca cggccaaugc aucuaccucg ucgacauguc ccaaaacuac ugcagaugcg      360

aagucggcua caccggaguc cgcugcgaac acuucuuccu cacaguacac caaccucucu      420

ccaaagaaua cgucgcccuc accgucauac ucauuauccu cuuccucauc accguagucg      480

gcuccacaua cuacuucugc cgcugguacc gcaaccgcaa auccaaagaa cccaaaaaag      540

aauacgaacg cgucaccucc ggcgaccccg aacuccccca aguauaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  4679
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt9)

<400>  4679
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgaaggcg aaaucacaac cuucaccgcc cucaccgaaa      120

aauucaaccu cccccccggc aacuacaaaa aacccaaacu ccuauacugc uccaacggcg      180

gacacuuccu ccguauacuc cccgacggca cagucgacgg cacccgagac cgcucugacc      240

aacacaucca acuccaacuc ucagccgaau cagucggcga agucuacaua aaauccaccg      300

aaacaggcca auaucucgca auggacaccg acggccuucu cuacggcucc caaaccccca      360

acgaagaaug ccucuuccuc gaacgccuag aagaaaacca cuacaacaca uacaucucca      420

aaaaacacgc agaaaaaaac ugguucguag gccucaaaaa aaacggcucc ugcaaacgcg      480

gcccccgcac ccacuacggc caaaaagcca uccucuuccu cccccuaccc gucucauccg      540

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  4680
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt9)

<400>  4680
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guagggguag gaggagggga uguagaagau gugacgccaa      120

ggccaggagg gugucaaaua agcggaagag gggcaagagg cuguaacggg auaccggggg      180

cagcggcgug ggaggcagcg cugccgagaa gacgaccacg aaggcauccg agugugaacc      240

cgcggucaag agcggcaggg agcccgagaa cgagagggag aagaacagag gaaaggccaa      300

guggaaguag auuaggggau aggggaagag ggagggcgcu accgggaggg agauugggag      360

ggcgagggag agggagagcg ccagagaggg uaggagggcg ggggcggggg agggggacag      420

cggcgccgag agcggcacca gcagcgagag ggagcaggcc agggccggcg gggacgaugg      480

cggcgggaag cauaacaaca cugccggcgu uaccggagga cggagggagu ggggcguucc      540

cgccagggca cuuuaaagau ccaaagaggu uguauugcaa aaacggaggg uucuuucuga      600

ggauacaucc agaugggaga guagauggag uaagggagaa aucggaccca cacauaaaac      660

ugcaauugca agcagaagag agagggguag ugagcauaaa aggggugugu gcaaacagau      720

accuagcgau gaaggaagau ggaagacugu uagcgucgaa auguguaacg gacgagugcu      780

uuuucuuuga aaggcucgag agcaauaacu auaacacaua caggagcagg aaguauacau      840

caugguaugu agcacucaag agaacgggac aauacaagcu agggagcaag acggggccgg      900

ggcaaaaggc aauacuauuu cuaccgaugu cggcaaagag cuagggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  4681
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt9)

<400>  4681
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uccucaccug gauccuaccc acccuccugu      120

accgcagcug cuuccacauc aucugccucg ucggaaccau aucccucgcc ugcaacgaca      180

ugacccccga acaaauggcc acaaacguaa acugcagcuc ccccgaacgc cacacccgcu      240

ccuacgacua cauggaaggc ggagacaucc gcguacgccg ccuauucugc agaacccaau      300

gguaccuacg cauagacaaa agaggcaaag ucaaaggcac acaagaaaug aaaaacaacu      360

acaacaucau ggaaauccgc accgucgcag ucggaaucgu agccaucaaa ggagucgaaa      420

gcgaauucua ccuagccaug aacaaagaag gcaaacuaua cgccaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa cuaauccucg aaaaccacua caacaccuac gccuccgcca      540

aauggaccca caacggcggc gaaauguucg uagcccucaa ccaaaaagga auacccgucc      600

gcggaaaaaa aaccaaaaaa gaacaaaaaa ccgcccacuu ccuccccaug gccaucaccu      660

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  4682
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt9)

<400>  4682
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuccucc ccuccgucgu ccucaaacuc uuccuagccg      120

caguccucuc cgcacucguc accggcgaau cccucgaacg acuccgacgc ggccuggccg      180

caggcaccuc caaccccgac ccaccaaccg ucucaacaga ccaacuacua ccccucggcg      240

gaggccgcga cagaaaaguc cgcgaccuuc aagaagcaga ccucgaccuc cuccgaguca      300

cccucuccag caaaccccaa gcccucgcca cacccaacaa agaagaacac ggaaaacgca      360

agaaaaaagg caaaggccuc ggcaaaaaac gcgaccccug ccuacgcaaa uacaaagacu      420

ucugcaucca cggggaaugc aaauacguca aagaacuacg cgcccccuca ugcauaugcc      480

accccggcua ccacggcgaa cgcugccacg gccucucccu ccccguagaa aaccgacucu      540

acaccuacga ccacaccacc auccucgccg ucgucgccgu cguccucucc uccguaugcc      600

uacucgucau cguaggccuc cuaauguucc gcuaccaccg ccgaggcggc uacgacgucg      660

aaaacgaaga aaaagucaaa cucggaauga ccaacuccca cuaaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  4683
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt9)

<400>  4683
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggucacga aacuccuccc agcacuacua cuacaacacg      120

uccuauuaca ccuccuccuc cuacccauag caauacccua cgcggaaggg cagcgaaaaa      180

gacgcaacac gauccacgag uucaagaagu ccgcaaaaac aacccuaauc aaaauagacc      240

ccgcccucaa aaucaaaacc aagaaaguca auaccgcaga ccaaugcgca aaccgcugca      300

cacgcaacaa aggccuccca uuuaccugca aagccuucgu uuuugacaaa gccagaaagc      360

aaugccuuug guucccauuc aacagcauga gcuccggcgu caagaaagag uucggacacg      420

aguucgaccu guacgaaaac aaagacuaca uccgaaacug cauaaucggc aaaggccgca      480

gcuacaaagg aacagucucc auaaccaaau caggcaucaa augccagccu uggagcucca      540

ugauacccca cgaacacuca uuccucccgu caagcuaccg agggaaagac cuacaagaaa      600

auuacugccg aaacccacgc ggggaagaag gcggacccug gugcuucacc ucaaacccag      660

aaguccgcua cgaaguaugc gacauccccc aaugcucaga aguugaaugc augaccugca      720

auggagaaag cuacagaggg cucauggacc acaccgaaag cggcaaaaua ugccaacgau      780

gggaccacca aacaccacac cgacacaaau uccuccccga acgauacccg gacaaagggu      840

ucgaugacaa cuacugccgu aaccccgacg gccagccacg cccauggugc uacacacuag      900

acccacacac ucgcugggaa uacugugcaa ucaaaacaug cgccgacaau accaugaacg      960

acacagacgu cccccuggaa acaaccgaau gcauccaagg ccaaggugaa ggcuaccgcg     1020

gcacggucaa uaccauaugg aacggcauac ccugccaacg augggacagc caauacccgc     1080

acgaacacga caugacacca gaaaacuuca aaugcaaaga ccuucgggaa aacuacugcc     1140

gaaaccccga cggauccgaa agccccuggu gcuucacaac cgaccccaac auccgcguag     1200

gauacuguuc acaaauccca aacugugaca ugagccacgg acaggacugc uacagaggua     1260

acggcaaaaa cuacaugggc aaccucuccc aaacacgauc cggacugacc ugcagcaugu     1320

gggacaagaa cauggaagau cuccauagac acaucuucug ggaaccagac gcaagcaaau     1380

uaaacgaaaa cuacugccga aaccccgacg acgacgccca cggccccugg ugcuacacag     1440

gaaacccucu gauucccugg gauuauuguc ccaucucccg cugcgagggc gacaccaccc     1500

ccacaaucgu gaaccuagac caccccguaa uaucaugcgc aaaaacgaaa cagcuccgag     1560

uugugaacgg cauaccaacu agaacuaaca ucggcuggau ggucucacua cgauaccgua     1620

acaaacacau cugcggaggu ucgcuaauaa aagaaagcug gguccucacc gcacgccaau     1680

gcuuccccag ccgggaucug aaagacuacg aagccuggcu gggaauacac gacguccacg     1740

guagaggaga cgaaaaaugc aaacaggucc ucaacguauc ccaacucgua uacggcccgg     1800

agggcaguga ccucguacuc augaaacuag cccgacccgc cguccuugac gacuucguau     1860

ccaccauaga ccuccccaac uacggcugca ccaucccaga aaagaccagc ugcagcgucu     1920

acggaugggg auacaccggc cuaauaaauu acgacgggcu acuccgcguc gcccaccugu     1980

acaucauggg caacgaaaaa ugcucccagc accacagagg caaaguaacc cuaaaugaaa     2040

gcgaaauaug cgcaggggcc gagaaaaucg gcaguggccc augcgaaggc gacuacgggg     2100

gcccccuagu augcgaacaa cauaaaaugc gcaugguccu cggagugauc guccccggac     2160

gaggcugcgc gaucccaaau cgcccaggca ucuucguccg cguggcuuac uacgccaaau     2220

ggauacacaa aauaauacua accuacaaag uaccccaaag cugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  4684
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt9)

<400>  4684
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuaaagcgg cggcaaucgg aauagaccuc ggaaccaccu      120

acucaugcgu gggcguuuuu cagcacggca aaguagaaau aauagcaaac gaucaaggaa      180

acaggacaac ucccucguac guggcauuua cagacacaga gagacugauu ggggacgccg      240

ccaaaaacca agucgcacug aacccccaga acacaguuuu cgacgcgaaa aggcucauag      300

gacgaaaauu cggagaccca gugguccaaa gugacaugaa gcacuggcca uuccaaguga      360

uaaaugacgg cgacaaaccc aagguacaag ucucguacaa aggcgaaacc aaggcauucu      420

acccagaaga gauaucgucc augguccuca caaagaugaa agaaauagcc gaagccuacc      480

ucggguaccc agucacaaac gcggucauaa ccguacccgc guacuucaac gacagccaac      540

gacaagcgac aaaagacgcc ggagucauag caggccucaa cguacugcgc auaaucaacg      600

aaccgaccgc ggcagccaua gccuacgggc uagaccgcac aggaaaaggg gagcgcaacg      660

ucuuaaucuu cgaccuaggc ggaggcacau ucgacgucuc aauacuaacc auagacgacg      720

gcaucuucga aguaaaagcc acagccgggg acacgcaccu aggcggcgaa gacuucgaua      780

accgccuagu aaaccacuuc guagaagagu ucaagagaaa gcacaagaaa gacauaagcc      840

aaaacaaacg ggccgugcgc aggcuaagga ccgcaugcga acgcgcaaaa cgaacccuca      900

gcucaaguac ccaagcaagc cuggaaaucg acagucucuu cgaaggaaua gacuucuaca      960

ccuccaucac ccgagcgcga uucgaagaac uaugcagcga ccuauuccgc ucgacacugg     1020

aaccggugga aaaagcacuc agagacgcga agcuagacaa agcccaaauc cacgaccuag     1080

uauugguggg aggcaguaca agaaucccaa aaguacaaaa gcuccuacaa gauuucuuca     1140

acggaaggga ccucaacaaa uccaucaacc ccgacgaagc aguggccuac ggggcagcag     1200

uccaggcagc cauacugaug ggagacaaaa gcgaaaacgu gcaagaccua cuccuccugg     1260

acguagcccc acuaagccua ggacucgaaa cagccggagg aguaaugaca gcacugauaa     1320

aaaggaacag caccaucccc acgaaacaaa cccaaaucuu cacaacguac ucagacaacc     1380

aacccggagu gcuaauacaa guauacgaag gcgagcgcgc aaugacuaaa gacaacaacc     1440

uccugggcag guucgagcua ucaggaauac caccggcacc acggggaguc ccgcaaauag     1500

aagugaccuu cgacauagac gccaauggca uacuaaacgu aaccgcaacc gacaaaucua     1560

ccgggaaagc aaacaagaua acgaucacga acgauaaagg gcgcuuaagc aaggaagaaa     1620

ucgaacgcau gguccaagaa gcagaaaaau acaaagccga ggacgaagua caacgcgaaa     1680

gagugagcgc gaaaaacgca cuagaaucau acgcguucaa caugaaaagc gcagucgaag     1740

acgaaggccu caaagggaaa auauccgagg ccgauaaaaa gaaaguacua gacaaaugcc     1800

aagaagucau aagcuggcua gacgccaaca ccuuagccga aaaagacgag uucgaacaca     1860

aaaggaaaga acuggaacaa guaugcaacc ccauuauauc cggccuauac caaggagcug     1920

gaggaccggg acccggcgga uucggagccc aaggccccaa aggaggaagu gggagcgggc     1980

ccacgauaga agaagucgac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4685
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt9)

<400>  4685
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgaaagccg cagccaucgg aauagaccuc ggcaccaccu      120

acucaugcgu cggcguauuc caacacggga aaguagagau caucgcaaac gaccaaggaa      180

acaggaccac accaucauac guagccuuca cagacaccga gcgccuaauc ggagacgccg      240

ccaagaacca aguugcgcuc aacccacaaa acacagucuu cgacgcaaaa cgacugauag      300

gccgaaaauu cggcgaccca gugguccaau ccgacaugaa gcacuggcca uuccaaguaa      360

ucaaugacgg agacaaaccc aaaguacagg ucagcuacaa aggagaaaca aaggccuucu      420

acccagaaga aauaagcuca augguccuga ccaaaaugaa agaaauagca gaggcuuacc      480

ucggcuaccc cguaacaaac gcggucauca ccguacccgc auacuucaac gacagccaac      540

ggcaagccac gaaagacgcc ggagucauag caggccuaaa cguacuccgc auuauaaacg      600

aaccaaccgc cgccgccauc gcauacggac ucgaccgaac aggcaagggc gagagaaacg      660

uacugaucuu cgaccucgga ggaggaacau ucgacgucag uauacucacg aucgacgacg      720

gaauauucga gguaaaggca acggcuggag acacacaccu aggcggagaa gacuucgaca      780

acaggcuugu caaccacuuc gucgaagagu ucaaacgaaa acacaagaaa gacauaagcc      840

aaaacaaaag ggccguccgu agacuaagaa ccgccugcga aagagcgaaa aggacacuca      900

gcuccucaac ccaagcaagc cuagaaauag acucacuauu cgaaggcauc gacuucuaca      960

ccucgaucac ccgugcacgu uucgaagaac uaugcagcga ccucuuccgc ucaacccuag     1020

aacccguaga aaaagcacua cgagacgcga aacuagacaa agcgcaaaua cacgaccugg     1080

uccuaguagg aggcucaaca agaauaccua aaguacaaaa acucuugcaa gauuucuuca     1140

auggccgcga ccucaacaaa agcauaaacc cagacgaagc cgucgcauau ggagccgcgg     1200

ugcaggcagc aauccuaaug ggagacaaaa gcgaaaacgu gcaagaccug cugcuccuag     1260

acguagcacc acucucacuu ggccucgaaa ccgcaggagg cguaaugacu gcacuuauca     1320

aaaggaacuc gaccauaccc accaaacaga cacaaaucuu cacuacauac ucggacaacc     1380

agcccggagu ccuuauccaa guauacgagg gcgaacgcgc gaugacaaaa gacaacaacc     1440

uacucggaag auucgaacuc ucaggaauac caccagcccc acgcggcguc ccacaaaucg     1500

aaguaacauu cgacaucgac gcgaacggaa uauuaaacgu cacagccaca gacaaaucga     1560

ccggaaaagc aaacaaaaua acaaucacaa acgacaaagg ccgacuuagu aaagaagaaa     1620

ucgagcgaau ggugcaagaa gcggagaaau acaaagcaga agacgaagua caaagagagc     1680

gaguauccgc caagaacgcc cucgaaucau acgccuucaa caugaaaagc gcggucgaag     1740

acgaaggccu aaaggggaag auaagcgaag cagacaagaa gaaaguacua gacaaaugcc     1800

aagagguaau cagcuggcua gacgcaaaca cccucgcuga aaaagacgag uucgaacaca     1860

aacgaaaaga acucgagcaa gucugcaacc ccauaaucuc gggccucuau cagggagcgg     1920

gaggacccgg cccagggggc uucggagcgc aaggacccaa aggcggcagc ggaagcggcc     1980

ccacaaucga agaaguagac uagggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4686
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt9)

<400>  4686
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccacagcca aggggaucgc aaucggcauc gaccuaggaa      120

ccacauauuc cugcguagga gucuuccagc acggcaaagu ggaaauaauc gcaaacgauc      180

aaggcaacag aacaacccca agcuacguag cauucaccga cacagagaga cugaucggcg      240

acgccgcgaa aaaccaagug gcaaugaacc cacagaacac cgucuucgac gccaaacggc      300

ucauaggcag aaaauucaac gaccccguag uacaagccga caugaaacuc uggcccuuuc      360

aagucauaaa cgaaggcgga aagcccaaag uccuaguaag cuacaaaggc gaaaacaagg      420

ccuucuaccc cgaagaaauc ucgagcaugg uccucaccaa gcugaaggaa acagcagaag      480

ccuuccuagg ccacccagua acaaacgccg uaauaacagu gccagcauac uucaacgaca      540

gccaacgaca agcgaccaag gaugcgggug uaauagcggg ccucaacguc cuacgaauca      600

uaaacgaacc uacagcggcc gccaucgccu acggacugga caaaggaggc cagggagaaa      660

gacacguacu gauauucgac cuaggaggcg gcaccuucga cgucucaaua cugaccaucg      720

acgauggcau cuucgaagua aaagccacug caggcgacac ccaccucggc ggcgaagacu      780

ucgacaaccg gcucgucagc cauuucgucg aagaauuuaa aaggaaacac aagaaagaca      840

ucucccagaa caaaagagca gucagacgac uucggaccgc gugcgaacgc gcaaaacgca      900

cgcuaagcag caguacacaa gcaaaccuag aaaucgacuc ccuuuacgaa ggaaucgacu      960

ucuacacauc aaucacccgc gcaagguucg aggagcucug cgccgaccuc uuccguggca     1020

cccuagaacc cgucgaaaaa gcacuccgcg acgccaaaau ggacaaggca aaaauacacg     1080

acaucguacu cgucgggggc ucaaccagaa uccccaaggu ccagcgccua cuacaagauu     1140

acuucaacgg acgagaccuc aacaaaagca uaaauccaga cgaagcgguc gcguacggcg     1200

cagcaguaca ggccgcgauc cuaauggggg acaaaagcga aaaaguccaa gaccuccucc     1260

ugcuagacgu agcaccgcuu ucccuaggcc uagaaacagc cggaggugua augaccgccc     1320

uaaucaaacg caacagcaca auacccacca aacaaaccca aaucuucacc acauacagcg     1380

acaaccagcc gggcguccuc auacagguuu acgaaggcga acgcgcaaug acaaaagaca     1440

acaacuuacu aggacgauuc gaccugaccg gcaucccacc agcacccaga ggcguccccc     1500

aaauagaagu aaccuuugac auagacgcca acggcauacu aaacguaaca gccacagaca     1560

aaaguacggg caaagucaac aaaaucacca uaaccaacga caaaggcagg cucucaaaag     1620

aagaaaucga acggaugguc cuagacgcag aaaaauacaa agcagaagac gaaguacagc     1680

gagagaaaau agcggccaaa aacgcacucg aaagcuacgc cuucaacaug aaaagcguug     1740

uauccgacga aggauuaaaa ggaaaaauaa gcgaaagcga caaaaacaaa auacucgaca     1800

aaugcaacga acuccugucc uggcuggaag uaaaccaacu cgccgaaaaa gacgaguucg     1860

accacaaacg aaaagaacuc gaacaaaugu gcaaccccau aaucaccaaa cuguaccaag     1920

gcgguugcac cggaccagcc ugcggaaccg gcuauguacc cggacgccca gcgacaggcc     1980

caaccaucga agaggucgac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4687
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt9)

<400>  4687
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgcacgcg gccccgcaau cgggaucgau cuaggcacca      120

cauacucgug cguaggcgua uuccaacacg ggaaagucga aaucaucgca aacgaccaag      180

gaaaccgcac cacccccagc uacguagccu ucaccgacac cgaacgacuc aucggagacg      240

cagccaaaaa ccagguagca augaacccaa ccaacacaau cuucgacgca aaaaggcuga      300

uaggccgaaa auuugaggac gccacggucc aaagugacau gaaacauugg cccuuccgcg      360

uaguauccga aggaggcaaa cccaaagucc aaguagaaua caagggcgag accaagaccu      420

ucuucccgga agaaauaucc agcauggucc ugaccaaaau gaaagaaaua gccgaagccu      480

accuuggggg aaaaguccac agcgccguca uaaccguucc agccuacuuc aacgacagcc      540

aacggcaagc cacgaaagac gcaggcacaa uaacaggacu caacguccuu cgaauaauaa      600

acgaaccaac cgcagccgcg aucgcauacg ggcucgacaa aaaggggugu gcagggggcg      660

agaaaaacgu guuaauauuu gaccuaggcg ggggcaccuu cgacguaagc auccucacca      720

uagaagacgg cauauuugaa gucaaaagca ccgccggaga cacacaccug ggaggagaag      780

acuucgacaa ucggauggua agccaccucg cagaagaguu caagcgcaag cacaagaaag      840

acauugggcc aaacaaaagg gccgugcgac gccucagaac cgcaugcgaa cgcgcaaaac      900

gcacccugag cucaaguacg caagcaagca ucgaaauuga cagucuguac gaaggaguag      960

acuucuacac aucaauaaca cgagcacgcu ucgaagaacu caacgccgac cucuuccgcg     1020

gaacacuaga acccgucgaa aaagcacucc gggacgcaaa acuggacaaa ggccaaaucc     1080

aagaaauagu acucgucggg ggauccaccc gaauaccaaa gauacagaaa cuacugcaag     1140

acuucuucaa cgggaaagaa cuaaacaagu cgauaaaccc cgacgaagca guagcguacg     1200

gcgccgccgu acaagccgcg auccugauag gagauaaaag ugaaaacgug caagaccuac     1260

ugcuccugga cgucacgccc cuaucacucg ggaucgaaac cgcuggcgga guaaugacac     1320

cccucauaaa aaggaacacc accauaccaa ccaaacaaac ccaaacauuc accaccuacu     1380

cggacaacca aucaucugug cuaguacaag uauacgaagg cgaacgggcu augacgaaag     1440

acaacaaucu acuagguaag uucgaccuaa caggcauacc cccggcaccc cgaggaguac     1500

cacaaauaga aguaaccuuc gacaucgaug caaacgggau acuaaacgua accgcagccg     1560

acaaaucgac cggaaaagaa aacaaaauca caaucacaaa cgacaaagga cgccucagca     1620

aagacgacau agaccgaaug guucaggaag cagagaggua caagagcgaa gacgaagcga     1680

accgagaccg aguggcggcc aaaaacgcac uggaaagcua caccuacaau auaaaacaaa     1740

caguugaaga cgaaaaacuc cguggaaaga ucagcgaaca agacaaaaac aaaauacuag     1800

acaaaugcca agaagucaua aacuggcugg accgaaacca gauggccgaa aaagaugaau     1860

acgaacacaa acaaaaagag cuagagcgcg uaugcaaccc cauaaucucg aaacuguacc     1920

aaggcggacc aggaggagga agcggaggag gaggaucggg cgcaagcggc ggcccgacaa     1980

ucgaagaggu cgacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  4688
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt9)

<400>  4688
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguaguag gcaucgaccu aggguuucag agcugcuacg      120

ucgcagucgc aagagcgggu ggcauagaaa caauagcaaa cgaauacagc gacagaugca      180

cccccgcaug caucucguuu ggccccaaaa auagaagcau uggagcugca gccaaaagcc      240

aagucaucag caacgcgaaa aacacgguac aaggcuucaa gcgguuucac ggaagggcau      300

ucagcgaccc cuucguugaa gcggagaagu ccaaccuagc guacgacauc guccaacuac      360

ccaccggacu gaccgguaua aaaguaacau acauggaaga agaaaggaac uuuacaacag      420

aacaaguaac cgccaugcuc cucagcaaac uaaaagaaac agcagaaucc guccucaaga      480

aacccgucgu cgacugcguc gugucggucc ccugcuucua caccgaugca gaaaggcgcu      540

cagucaugga cgcgacgcag auagcggggc ucaacugccu acgccuaaug aacgagacga      600

cagcagucgc ccucgccuac ggcaucuaca aacaagaccu ucccgcacua gaagaaaaac      660

cccgaaaugu cgucuucguc gacaugggac acucagcaua ccaaguaucu guaugcgcgu      720

ucaaccgagg caaacuuaaa gugcuggcca ccgccuucga cacaacacuc ggcggccgga      780

aauucgacga aguccuagua aaucacuucu gcgaagaguu cggcaagaaa uauaaacuag      840

auauaaaauc caaaauacgc gcccuccugc gcuugagcca ggaaugcgaa aaacucaaaa      900

agcuaaugag cgcaaacgcg ucagaccugc cacugagcau agaaugcuuc augaacgacg      960

uagacguauc cggaaccaug aaccggggaa aauucuuaga aaugugcaac gaccuccuag     1020

cacgcguuga acccccucua agaucugugc uggaacaaac aaaacugaag aaagaagaca     1080

ucuacgcagu agaaaucguc ggaggggcaa cucgaauacc ggccgucaaa gagaaaauca     1140

gcaaauucuu cgggaaggaa cucagcacca cccugaacgc agacgaagcg guaaccaggg     1200

gcugcgcgcu ccaaugcgcc auacugucac cagccuucaa aguacgagag uucagcauaa     1260

cagacguggu cccauaccca auaagccucc gauggaacuc accagcagaa gaaggcucga     1320

gcgacugcga aguauucagc aaaaaccacg cagcaccauu cuccaaaguc cucacguuuu     1380

accggaaaga accguucacc cucgaggcau acuacuccuc accccaagac cuccccuacc     1440

ccgacccagc caucgcacaa uucagcgucc aaaaggucac uccccagagc gacggcagua     1500

gcagcaaagu caaagucaaa guccgcguca acguacacgg gaucuucagc guaucaucag     1560

ccagccucgu ggaaguccac aagagcgagg aaaacgagga accaauggag accgaccaaa     1620

acgccaaaga agaagagaaa augcaagucg accaggaaga accccacgua gaagaacagc     1680

agcagcaaac ccccgcggaa aacaaagcag aauccgaaga aauggaaacc ucgcaagccg     1740

gcaguaaaga caagaaaaug gaccaaccac cccaagcaaa gaaagcaaaa guaaaaacgu     1800

ccacaguaga ccugccaaua gagaaccaac uacuuuggca aauagaccga gaaaugcuaa     1860

acuuauacau cgagaacgaa gggaaaauga ucaugcaaga uaaacuagaa aaagaaagaa     1920

acgaugccaa aaacgcaguc gaagaguacg uuuacgagau gcgggacaaa cuaagcggcg     1980

aguacgagaa guucgucucc gaggacgacc gcaacagcuu cacacugaaa cucgaagaca     2040

ccgaaaacug gcuauacgaa gacggcgaag accaaccaaa gcaaguauac gucgacaagc     2100

ucgcggaacu caaaaaccuc ggccaaccaa uaaaaauccg guuccaagaa agcgaggaga     2160

gaccaaagcu auucgaagaa cucggaaaac aaauccagca auacaugaaa auuauaucaa     2220

guuucaaaaa caaagaagau caauacgauc aucuggacgc cgcagacaug acaaaaguag     2280

aaaaaucgac caacgaagca auggaaugga ugaacaacaa auuaaaucug caaaacaaac     2340

aaagccuaac cauggacccc guaguaaaau caaaagagau cgaagccaaa aucaaagaac     2400

ucaccuccac augcagcccc aucauaagca aacccaagcc caaagucgaa ccacccaaag     2460

aggaacagaa aaacgcagaa caaaacggcc ccgucgaugg acagggcgau aaccccggac     2520

cgcaagccgc cgaacaaggc acggacacag ccgugcccuc agacagcgac aagaaacuac     2580

cagaaaugga caucgacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  4689
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt9)

<400>  4689
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucagucgucg gaauagaccu cggauuccuc aacugcuaca      120

uagccguagc acgcuccgga gguauagaga caaucgccaa ugaguacucc gacaggugua      180

cccccgcgug caucagccug ggcucccgca cucgcgccau cggcaacgcg gcgaaguccc      240

aaaucgucac caacgucaga aacacaaucc acggauucaa gaaacuccac ggacgauccu      300

ucgacgaccc cauaguccaa accgagcgca uacgccugcc cuacgaacua cagaaaaugc      360

caaauggcag cgccggcgua aaaguccgcu accucgagga ggaacgcccc uucgccaucg      420

aacaagucac aggcaugcua uuagcaaagc ucaaagagac cuccgaaaau gcacucaaga      480

aacccguggc agacugcgua aucagcauuc cguccuucuu cacagacgca gagcgacggu      540

cagucauggc agccgcacaa gucgccggcc ugaacugucu ccgacugaug aaugagacaa      600

cggccgucgc ccucgcauac ggcaucuaca aacaagacuu accuccgcuc gacgaaaaac      660

cgagaaacgu cgucuucauc gacaugggac acagcgcaua ccaaguccuc guaugugcau      720

ucaacaaagg aaaacuaaaa guucuugcca ccacauucga uccauaccuc ggaggccgca      780

acuucgacga agcacucguu gacuacuucu gugacgaguu caaaacaaaa uacaaaauaa      840

acgucaaaga aaacagccgc gcccuucucc gucuauacca ggagugcgaa aaacucaaga      900

aacucaugag cgccaacgcc agcgaucucc cacuaaacau cgaauguuuc augaacgacc      960

uggacgugag uuccaaaaug aaccgugccc aauucgagca acucugcgcc agcuuacuag     1020

caagaguaga accaccacuc aaagcgguca uggagcaagc caaucuccaa cgggaagaca     1080

ucagcuccau agagaucguc gggggagcaa cccgaauacc cgcuguaaaa gaacaaauaa     1140

cuaaauucuu ccuaaaagac auaagcacaa cccugaacgc cgacgaagca gucgcccgag     1200

gcugcgcacu ccagugcgcc auacucuccc ccgcguucaa aguacgcgag uucaguauca     1260

cagaccucgu accauacuca aucacccuac gcuggaagac aucuuucgaa gacggcuccg     1320

gagaaugcga agucuucugc aaaaaucacc ccgcccccuu uuccaaaguc aucacauucc     1380

acaaaaagga accguucgaa cucgaagcgu uuuacacgaa ccuccacgag guaccauacc     1440

ccgacgcgag aauaggauca uucaccauac aaaacguauu cccacaaucc gacggcgauu     1500

cauccaaggu caaagucaaa guaagaguca acauacacgg caucuuuuca gucgccagcg     1560

ccagcgugau ugagaaacaa aaccuugaag gcgaucacag cgacgccccc auggaaaccg     1620

aaacgagcuu caagaacgaa aacaaggaca acauggacaa gaugcaggua gaccaagagg     1680

aaggacacca aaaaugccau gcagaacaca cacccgagga agaaaucgac cacaccggag     1740

ccaaaacgaa gucugccguc agcgauaagc aggaccgucu caaccaaacc cucaagaaag     1800

gcaaaguaaa aagcauagac cuaccaaucc aaagcucacu cugccgccaa cucgggcaag     1860

accuccuaaa cuccuacaua gaaaacgaag gcaaaaugau caugcaagau aaacuagaaa     1920

aagaacgcaa cgacgccaaa aacgcagucg aagaauacgu cuaugacuuc cgagaccggc     1980

ucggaaccgu cuacgaaaaa uucauaaccc ccgaggaccu aucaaaacua agcgcugucc     2040

uagaagacac cgagaacugg cuauacgaag acggagagga ccaaccaaaa caaguauacg     2100

uagacaagcu ccaggagcuc aagaaauacg gccaacccau ccagaugaaa uacauggagc     2160

augaagaaag acccaaagca cucaacgacc ucggcaagaa aauccagcuc guuaugaaag     2220

uaauagaagc cuaccgaaac aaagacgagc gcuacgacca ccuagaccca accgaaaugg     2280

aaaaagucga aaaaugcauc agcgaugcca ugagcuggcu caacuccaag augaacgcgc     2340

agaacaaacu aucccucacc caagaccccg uaguaaaagu aucagaaaua gucgcaaaau     2400

cgaaagaacu ggacaacuuc ugcaacccaa ucaucuacaa gccgaaaccu aaagcagagg     2460

ugccagaaga caaaccaaaa gcaaauagcg aacacaacgg accaauggac gggcaauccg     2520

gaacagaaac caaaagcgau agcacaaaag acucauccca gcacacaaaa agcucagggg     2580

aaauggaggu cgacuaggga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  4690
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt9)

<400>  4690
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuaagcc uaguagcggc aaugcuccug cucuuaagcg      120

ccgcaagagc agaagaagag gacaagaaag aggacgucgg caccgucguc ggcauagacc      180

uaggcaccac guacagcugc gucgggguau ucaaaaacgg aagagucgaa aucaucgcca      240

acgaccaagg caacagaauc acacccagcu acguagccuu cacccccgaa ggagaacgcc      300

ucauaggaga cgcggccaaa aaccaacuca ccagcaaccc agagaacaca guauucgacg      360

caaaacggcu aaucggccgg accuggaacg accccagcgu ccaacaagac auaaaauucc      420

uccccuucaa ggucgucgag aagaaaacaa aaccauacau ucaagucgac auaggaggag      480

gucaaacgaa aacauucgca cccgaggaga uaagcgcaau gguacucacc aaaaugaaag      540

aaaccgcaga agcauaccuu ggaaagaaag ucacgcaugc cgucgucaca gucccagccu      600

acuucaacga cgcacaaaga caggcgacca aagacgccgg cacaaucgca ggacugaacg      660

uaaugcgcau aaucaacgag cccaccgccg cagccaucgc uuacgggcua gacaaacgag      720

aaggagagaa aaacauccuc guguucgacc uaggaggagg cacauucgac gucagccucc      780

uaacaaucga caacggagug uucgaagucg uagccaccaa cggcgacacg caccucggag      840

gagaggauuu cgaccaaaga guaauggaac acuuuaucaa acuauacaaa aagaaaacag      900

gcaaagacgu acgaaaagac aacagagccg ugcaaaaacu ucgacgugag guagaaaaag      960

ccaaacgagc acugucgagc caacaccaag caagaauaga aaucgagagc uucuacgaag     1020

gcgaagacuu cagcgaaacc cucacucgag caaaauuuga agaacuaaac auggaccucu     1080

ucagaagcac aaugaagcca guacagaagg ugcucgaaga cucagaccuc aagaaaagcg     1140

auauagacga aaucguccuc gucgggggca gcacccggau accgaaaauc caacaacucg     1200

ucaaagaguu cuucaacgga aaagaaccua gccguggaau caacccagac gaagccgucg     1260

cguacggagc cgcgguccag gcaggcgucc uaucaggcga ucaagacaca ggcgaccucg     1320

uccuacuaga cgugugccca cuaacacucg gaaucgaaac cgugggcgga gucaugacca     1380

aacuaauacc ccgcaacaca gucguuccca cgaagaaaag ccaaauauuc agcacggccu     1440

cagacaacca gcccaccgua acaaucaaag ucuacgaagg ggaacgccca cucaccaaag     1500

acaaccaccu ccugggcacg uucgaucuga caggcauacc acccgcgccc cgcggagucc     1560

cgcaaaucga aguaacauuc gaaauagacg ugaacgggau acugcgcguc acagccgaag     1620

acaaaggaac cggaaacaaa aacaaaauca caauaacaaa cgaccaaaac cgccuaacac     1680

cagaagaaau agaaagaaug guaaacgacg ccgaaaaauu cgcagaagag gacaagaaac     1740

uaaaagaacg cauagacacc cgaaacgaac ucgaaucaua ugcauacucc cucaaaaacc     1800

agaucggcga caaagaaaaa cuagggggca aacugagcuc cgaggacaag gaaacaaugg     1860

aaaaagcagu agaggagaaa aucgaauggc uggaaagcca ucaagacgca gacauagagg     1920

acuucaaagc caagaagaaa gaacuugaag agaucguaca accaauaauc ucaaaacucu     1980

acggcucggc aggaccacca ccgacaggag aagaagacac ggccgaaaaa gacgaacugu     2040

agggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  4691
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt9)

<400>  4691
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagccccaa gagaacuagc cguggggauc gaccucggga      120

caacauacuc cugcguaggc guguuccaac aaggaagagu cgaaauauua gcaaacgacc      180

aaggcaacag gaccacacca ucguacguag cguucacaga cacagaacgc cuagugggag      240

acgcagcaaa gucgcaagca gcacuaaauc cacacaacac ggucuucgac gcaaagaggc      300

uaauaggaag gaaguucgcc gacacaaccg uucaaagcga uaugaagcac uggccauuca      360

gagucgucuc ggaaggaggg aaaccaaaag ugcgggucug cuacagaggc gaagacaaaa      420

cauucuaccc agaagagauc uccagcaugg uacugagcaa aaugaaggaa acagccgaag      480

ccuaccucgg ccaaccaguc aagcacgcgg ucauaaccgu acccgccuac uucaaugaca      540

gccagcgcca agccacaaaa gacgccgggg caauagccgg acuaaacgua cuacgaauca      600

ucaacgaacc cacggcagca gcgauugcau acggccuaga ccgaaggggc gccggagaac      660

gcaauguccu gauauucgac cugggagggg gcacauuuga cgucuccgua cuaucaauag      720

acgcaggagu auucgaagug aaagcgacgg caggagacac gcaccuaggc ggcgaagacu      780

ucgacaaccg ucuagugaac cacuucaugg aagaguucag gcgaaaacac ggaaaagauc      840

ucagcggaaa caaacgcgca cuccgcaggc uaagaaccgc augcgaacgc gcaaaaagga      900

cccuaagcuc cucgacacag gccacccucg aaauagacuc ccuauucgaa ggagucgacu      960

ucuacacaag caucacccgc gcgcgauucg aagaacuaug cagcgaccuu uuccgcucaa     1020

cccuagaacc agucgaaaaa gcucuccgcg acgcaaaauu agacaaagca caaauccacg     1080

augucguccu aguaggcggc ucaacgcgca uaccaaaagu acaaaagcuc cugcaagacu     1140

ucuucaacgg gaaagaacua aacaaaucca uaaaccccga cgaagcgguc gccuacggcg     1200

cggcgguaca agcagcgguc cugaugggcg acaagugcga aaaagugcaa gaccuacuac     1260

uccucgacgu cgccccauua agccucggac uggagacggc aggaggagua augacaacac     1320

uaauccagcg aaacgcgacc auacccacaa agcaaaccca aaccuuuacc acguacucag     1380

acaaccaacc gggagucuuc auccaaguau augagggcga acgcgcaaug acaaaagaca     1440

acaaccucuu gggccgcuuc gaacucuccg gcaucccacc cgcgccccga ggcguaccgc     1500

aaauagaagu gaccuucgac auagacgcca acgggauacu aagcguaacc gcgacagacc     1560

ggucaaccgg caaagcgaac aaaaucacaa ucaccaacga caaaggacgg cuaagcaaag     1620

aagaaguaga acgcaugguc cacgaagccg aacaauacaa agccgaagac gaagcccaac     1680

gugaccgcgu cgcagcgaaa aacucacucg aagcccacgu guuccacguu aaaggauccc     1740

uccaagaaga aagccugcgc gacaagauac ccgaagaaga ccggagaaaa augcaggaca     1800

aaugccguga aguacucgcc uggcucgaac acaaccaacu agccgaaaaa gaagaauacg     1860

agcaucaaaa acgagaacug gaacaaauuu gcagacccau auuuucgaga cuguacgggg     1920

gcccaggcgu cccaggaggc ucaagcugcg gaacccaagc cagacaagga gaccccagca     1980

caggaccaau cauagaggaa guagacuagg gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  4692
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt9)

<400>  4692
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcacccc gcgaacucgc aguaggcauc gaccuaggca      120

ccaccuacuc cugcguaggc gucuuccaac aaggccgcgu agaaauacuc gccaacgacc      180

aaggcaaccg caccaccccc uccuacgucg cauucaccga caccgaacgc cucguaggcg      240

acgccgcuaa aucccaagcc gcccuaaacc cccauaacac cgucuucgac gccaaacgac      300

ucaucggccg aaaauucgca gacaccaccg uacaauccga caugaaacac uggccuuucc      360

aagucguauc agaaggagga aaaccaaaag uccgcgucug cuaccgcgga gaagacaaaa      420

cuuucuaccc cgaagaaaua uccagcaugg uccuaucaaa aaugaaagaa accgccgaag      480

cauaccucgg ccaacccguc aaacacgccg ucaucaccgu cccaaccuac uucuccaacu      540

cccaaagaca agccaccaaa gaugcaggcg ccauagccgg ccuaaaagua cuccccauca      600

ucaacgaggc caccgccgca gccaucgccu auggacuaga ucgccgcggc gccggcaaac      660

gaaacguccu gauauucgac cucggcggcg gcaccuucga cgucucagua cucagcauag      720

acgcaggcgu cuucgaagua aaagcaaccg caggagauac acaucucggc ggcgaagacu      780

ucgacaaucg acuugucaac cacuucaugg aagaguucag acgcaaacac ggcaaagacc      840

uaucaggcaa caaacgcgcc cuacgccgcc uacgaaccgc cugcgaaaga gccaaacgaa      900

cacccagcuc cucuacgcaa gcaacacucg aaauagacuc ccucuucgaa ggcgucgacu      960

ucuacaaauc caucacccga gcacgauucg aagaauuaug cuccgaccug uuccgcagca     1020

cccucgaacc cguagaaaaa gcccucagag acgcaaagcu ggacaaagcc caaauccacg     1080

acuucguccu cggaggcggc cuccacuccc acccccaagg cgcagaagua gcugcaggcc     1140

uccuacaacg acagggagcc gaacaagaac accaacccua aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  4693
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt9)

<400>  4693
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaaaaggac cggccgucgg aaucgaccuc ggcaccaccu      120

acagcugcgu cggcguguuc caacacggaa aaguggaaau caucgcaaac gaucaaggca      180

acaggaccac acccucguac guggcauuua ccgacaccga acgccucauu ggagacgcgg      240

ccaaaaacca gguagcaaug aaccccacca acaccgucuu cgacgcaaaa aggcuaaucg      300

gcagacgauu cgacgacgca gucguccaga gcgacaugaa acacuggcca uucauggugg      360

ucaaugacgc aggccgacca aaaguccaag ucgaauacaa aggcgaaacc aagagcuucu      420

accccgaaga aguauccagc auggugcuga ccaaaaugaa agaaauagca gaggcauacc      480

uaggaaagac cgucacgaac gcagucguga caguacccgc auacuucaac gacucacaac      540

gccaagccac aaaagacgcc ggaacaauag ccggccuaaa cguacuacgc auaauaaacg      600

aaccaacagc agcagcaauc gccuacggac ucgacaaaaa ggucggggcc gaacgcaacg      660

uccuaaucuu cgaucuagga ggagggacau ucgaugucag cauccugaca auagaagacg      720

ggauauucga agucaaaagc acagccggcg acacccaccu cggaggagaa gauuucgaca      780

accgcauggu caaccacuuu auagccgagu ucaagcgcaa gcacaagaag gacaucagcg      840

aaaacaaacg agccguacgc cgacuacgca ccgccugcga acgagcaaaa cgcacccugu      900

caagcagcac gcaagcgagc auagagaucg acagccucua cgaaggcaua gacuucuaca      960

cauccauaac gcgagcacgg uucgaagaac ucaacgccga ccuguuccgc ggcacccuag     1020

acccaguaga aaaagcccua cgagacgcca aacucgacaa aucacaaauc cacgacauag     1080

uucuggucgg cggcuccaca agaaucccua aaauccaaaa acuacuccaa gacuucuuca     1140

acggaaaaga acucaacaaa agcauaaacc ccgacgaagc aguggcguac ggagcagccg     1200

uccaagccgc gauccuaucc ggcgacaaga gcgaaaacgu ucaagaccuu cuccucuugg     1260

acguaacccc gcuaucauua ggaauagaaa ccgcgggagg aguaaugaca guacuaauca     1320

aaaggaacac uacaauaccg accaaacaaa cacaaaccuu cacgacauac ucagacaacc     1380

aaccaggcgu gcucauacaa gucuaugaag gagaacgcgc aaugacaaaa gacaacaacc     1440

uacucggcaa guucgaacuc acagggaucc cacccgcacc ccgcggagua ccacaaauag     1500

aaguaaccuu cgacaucgac gccaacggaa uccucaacgu cagcgccguc gacaaaucaa     1560

caggaaaaga gaacaaaauc acgauaacaa acgacaaagg gcgccugagc aaagaagaua     1620

ucgaacgaau gguucaggaa gccgagaaau acaaagcaga ggacgaaaag caacgcgaca     1680

aagucagcuc caaaaacucc cuagaaucau acgcguucaa caugaaagcg acggucgaag     1740

acgaaaaacu acaaggcaaa auuaacgaug aggauaaaca gaaaauacua gacaagugca     1800

acgaaaucau aaacuggcuc gacaagaacc aaacagcaga aaaagaagag uucgaacauc     1860

aacaaaaaga acucgaaaaa gucugcaauc ccauaauaac caaacuguac caaagcgcgg     1920

gcgggaugcc cggcgguaug ccgggaggcu uccccggagg cggcgcccca ccaagcggcg     1980

gcgcauccuc aggcccaacc aucgaagaag ucgacuaagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  4694
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt9)

<400>  4694
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaagcgcca gccgcgcagc cgcggcgagg cuaguaggcg      120

cagcggcaag uagaggaccg acggcggcaa gacaccaaga cucauggaac ggccugagcc      180

acgaggcguu cagacuggug agccgacgcg acuacgcaag cgaggccauc aaaggagcag      240

ucgucggaau cgaccuaggg acgacgaacu cgugcguagc agugauggag ggaaagcagg      300

cgaagguccu ggagaacgcg gaaggagcga gaaccacgcc aucagucgua gcauucaccg      360

cggacggaga gaggcucgug ggaaugccag cgaaaaggca ggcaguaaca aacccaaaca      420

acaccuucua cgcgacaaaa aggcuaauag guagaagaua cgacgaucca gaagugcaaa      480

aggacaucaa aaacguaccc uucaagauag uacgagccag caacggagac gcauggguag      540

aggcacaugg caagcuauau agcccgagcc agauaggggc guucguccuc augaagauga      600

aggaaacggc agagaacuac cugggacaca cggcaaagaa cgcggucaua acagugccag      660

cguacuucaa cgacagccaa cggcaagcga caaaggacgc agggcagaua aguggacuca      720

acguccuacg cgucauaaac gaaccaacag cggcugcccu cgcauacggg cucgacaaga      780

gcgaagacaa aguaauagca guauacgacc ugggcggagg cacauucgac auaucuauac      840

uagaaaucca gaaaggggua uucgaaguaa aguccacaaa cggcgacacg uuccuuggag      900

gggaagacuu cgaccaagcg cuauugcguc acaucguaaa ggaguucaag agagagacag      960

gaguagaccu cacaaaagac aacauggcgc ugcaacgagu aagagaagca gcagaaaaag     1020

cgaaguguga acuaagcucu agcguacaaa cagacauuaa ccucccauau cucacaaugg     1080

acaguucagg gccgaaacac cuaaacauga agcucacaag agcccaguuc gagggaauag     1140

ugaccgaccu aauccgcagg acaauagcgc cgugccaaaa ggcgaugcag gacgcagaag     1200

ugagcaagag cgacaucgga gaagucauau uaguaggggg aaugaccagg augccgaaag     1260

ugcaacagac ggugcaggac cuguucggca gagcaccgag caaggcagua aacccagacg     1320

aggcaguagc gaucggagcg gccauacaag ggggaguacu ugcgggagac guaacggacg     1380

uacuacuauu ggacgugacg ccauuaagcc uaggaauaga aacacuaggu ggcguguuca     1440

cuaaacucau caaucgaaac accacgauac ccacaaagaa aucacaagug uucagcacag     1500

cggccgacgg acagacccag gucgagauaa aaguaugcca aggagagcga gaaauggccg     1560

gggacaacaa acuacucggg caauucacac ugauaggaau accgccagca cccaggggag     1620

uaccccagau agagguaaca uucgacaucg acgcgaacgg aauaguccac gucagcgcaa     1680

aagacaaagg aacuggcagg gagcaacaaa uagugaucca aagcagcggc ggacugagca     1740

aggacgacau agagaacaug gugaaaaacg cggaaaaaua cgcggaggag gacaggagaa     1800

agaaagaaag gguagaagca guaaauaugg cggaagggau aauacacgau accgagacca     1860

agauggaaga guucaaggau caacucccag cggacgaaug caacaaauua aaagaagaaa     1920

uaagcaagau gagggaacua cuagcgcgca aagauagcga aacgggagaa aacauaagac     1980

aagccgcgag cagucuccag caggccagcc uaaaacuauu cgaaauggcg uacaagaaaa     2040

uggcaagcga aagagaaggg agcgggagca gcggaacagg agagcaaaaa gaagaucaga     2100

aagaagagaa gcaguaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  4695
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt9)

<400>  4695
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaaag aggcaggcgg aagcgacgga ccccgagaaa      120

cagccccaac auccgccuac uccagcccag caagaucacu cggcgacacc ggcaucacac      180

cacucucacc gucucacauc gucaacgaca ccgauucaaa cguauccgag caacaauccu      240

uccuaguagu cgucgccguc gacuucggga caaccuccuc cggcuacgca uauuccuuca      300

caaaagaacc cgaaugcauc cacgucaugc gccgcuggga aggaggagac cccggcguau      360

ccaaccagaa aacgcccacu accauccuac uaacccccga acgaaaauuc cacuccuucg      420

gcuacgcugc ccgagacuuc uaccacgacc ucgacccaaa cgaagccaaa caauggcucu      480

accuagaaaa guucaaaaug aaacuucaua ccacaggcga ccucaccaug gacaccgauc      540

uaaccgccgc aaacggcaag aaagugaaag cucuugaaau cuucgccuac gcccuucaau      600

acuucaaaga acaagcacua aaagaacucu ccgaccaagc aggcucagag uucgaaaacu      660

ccgacguucg cugggucauc acaguccccg caauauggaa acaacccgcc aagcaauuca      720

ugcgacaagc agcauaccaa gccggucucg caagcccaga aaauucagaa caauuaauca      780

uagcacucga acccgaagcc gcguccauau acugccgcaa acuucgccuc caccaaauga      840

uagaacucuc cucaaaagcc gcugucaacg gguacuccgg uagcgacaca gucggcgccg      900

gcuucacaca agccaaggag cacauacgcc gcaaccgcca aucgcgaaca uuccucgucg      960

agaacgucau cggagaaauc uggucagaac ucgaagaagg cgacaaauac gugguagucg     1020

acagcggcgg cggaaccgug gaccuaaccg uccaccagau acgccugcca gaagggcacc     1080

uuaaagaauu guacaaagcc acaggaggac ccuacggauc auuaggaguc gacuacgagu     1140

ucgaaaagcu gcucuacaaa aucuucggcg aagauuucau ugaacaauuc aaaauaaaac     1200

gccccgccgc augggucgau cugaugauag ccuucgaauc acguaaacgc gcagccgcuc     1260

ccgaccgaac caauccacuc aacaucaccc uacccuucuc auucaucgac uacuauaaga     1320

aauuccgcgg gcacuccguc gaacaugcuc uccgaaaauc aaacgucgau uucgucaaau     1380

ggucauccca aggcaugcuc cgcaugucac cggacgccau gaacgcacua uucaaaccca     1440

cuauagacuc aauaaucgaa caccuacgcg accucuucca aaagcccgaa guaagcacag     1500

ucaaauuccu cuuccucgug ggcggguucg ccgaagcccc acuccuccaa caggccgucc     1560

aggccgcauu cggagaccag ugccguauca uaaucccaca agacguaggc cuaaccauac     1620

ucaaaggcgc aguccuauuc ggccuagacc ccgccgucau uaagguccgc cguucccccu     1680

uaacauacgg agucggcguc cuuaaccgcu augucgaagg aaaacaccca cccgaaaagc     1740

uccuagucaa ggacggcacc cgauggugca ccgacgucuu cgacaaauuc auauccgcag     1800

accaaagcgu ugcacucggc gaacuuguca aacgaucaua cacccccgcg aaacccucac     1860

aauuagucau agucauaaac aucuacuccu cagaacacga caacguuucc uucaucaccg     1920

accccggcgu aaagaaaugc ggaacccuca gacuggaccu caccggcaca uccggcacug     1980

ccguacccgc acgacgcgaa auacaaaccc ucaugcaguu cggcgacacc gaaaucaaag     2040

caacugccau cgacauagcc acaucaaaau ccguaaaagu aggaaucgac uuccuaaacu     2100

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  4696
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt9)

<400>  4696
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuagcagucc ccgaaauggg ccuacaaggc cucuacaucg      120

gcuccagccc cgaacguuca cccguacccu caccaccagg cucaccaaga acccaagaaa      180

guugcggcau cgccccacuc acgcccuccc aaucccccaa gcccgaaguc cgagcacccc      240

aacaggcuuc auucucuguc gucguagcaa uagacuucgg aaccaccucu agcggcuacg      300

cuuucucauu cgccagcgac cccgaagcca uccacaugau gcgcaaaugg gaaggaggag      360

accccggugu agcacaccag aaaaccccaa ccugccuacu ccucacaccc gaaggagccu      420

uccacagcuu cggcuacacc gcccgagacu acuaccacga ccucgacccc gaggaggcuc      480

gugacuggcu cuacuucgaa aaauucaaaa ugaaaaucca cuccgccacc gaccucaccc      540

ucaaaacuca acuagaagcg guuaacggaa aaacaaugcc cgcccuagaa guuuucgcac      600

acgcccugcg cuucuuccga gaacacgcac uccaagaacu ucgcgaacaa agcccgagcc      660

uuccugaaaa agacaccguu cgaugggucu ugacaguccc cgcaauaugg aaacaaccgg      720

cgaaacaauu caugcgagaa gcagccuacc uagccggacu gguaucccga gaaaacgccg      780

agcaacuacu caucgcacuc gaacccgaag cugcauccgu cuacugccgc aaacuacgcc      840

uccaccaacu ccucgaccug uccggccgcg caccaggagg cgguagauug ggugagcgac      900

gcaguauaga caguuccuuu cgacaagcac gcgaacagcu acgccgaagc cggcacuccc      960

gaacuuuccu uguagaauca ggcgucggcg aacucugggc cgaaaugcaa gcaggagaca     1020

gauacguagu ugcggacugc ggcggcggca ccguugaccu gacaguccac caauuagaac     1080

aaccacacgg cacucucaaa gaacuuuaca aagcauccgg cggacccuau ggcgccguag     1140

gagucgacuu agcauuugaa caacuccugu gcagaaucuu cggggaagac uuuauagcaa     1200

ccuucaaaag acaaagaccc gcagccuggg ucgaccuuac caucgcauuc gaagcacgga     1260

aacgaacagc cggcccacac cgagcaggag cccugaacau cagccuacca uucucauuca     1320

ucgauuucua ccggaaacaa cgcggccaca acgucgaaac agcccuccgg cgaagcagcg     1380

ucaacuucgu caaaugguca ucccaaggaa ugcuacgaau guccugcgaa gcaaugaacg     1440

aacucuucca accaaccguc ucgggcauca uccaacacau cgaagccuua cuagcccgcc     1500

cagaaguaca aggagucaaa cuccucuucc uagucggagg cuucgcagag uccgcagucc     1560

uacaacacgc gguucaggcc gccuuaggag cacgcggccu ccgagucgug guaccccacg     1620

acguaggccu cacaauccua aaaggcgccg uucucuucgg gcaagcuccc ggcgucguac     1680

gcguacgccg cagcccacua accuacggcg uuggcguacu caaccgcuuc gucccgggaa     1740

gacacccacc cgaaaaacuc cuaguccgag acgguagacg cuggugcacc gacgucuuug     1800

aaagauucgu ggccgccgaa caaucagucg cccucggcga agaaguccga cgcagcuacu     1860

gccccgcacg ccccggccaa cgacgcgucc ucaucaaccu auacugcugc gcagcagaag     1920

acgcacgcuu uauaaccgac cccggcgucc gaaaaugcgg cgcacucuca cucgaauuag     1980

aacccgcaga cugcggucaa gacaccgccg gagccccgcc cggaagacga gaaauccgcg     2040

ccgcaaugca auucggcgac accgaaauca aagucacagc cgucgauguc uccacaaacc     2100

gaagcguaag ggccucgaua gacuuccuaa guaacuaggg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  4697
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt9)

<400>  4697
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaagagaaa ugacaauccu uggcuccgcc gugcuaaccc      120

uccuacuagc cgguuaccuc gcccaacagu accuaccccu ccccacccca aaagucaucg      180

gaaucgaucu cggcaccacc uacugcucag ucggcgucuu cuuccccggc accggaaaag      240

uaaaaguuau accggacgaa aacggccaca ucuccauccc cucaaugguc uccuucaccg      300

acaacgacgu cuacgucggc uacgaaagcg uggaacucgc cgacuccaac ccccaaaaua      360

caauauacga cgccaaacgc uucaucggca aaaucuucac cgccgaagaa cucgaagccg      420

aaauaggccg cuacccuuuc aaagugcuca acaaaaacgg cauggucgag uucuccguca      480

ccagcaacga aacaauaaca guaucgccag aauacgucgg cucccgccuc cuccuuaaac      540

uaaaagaaau ggcagaagcc uaccuaggca ugcccgucgc caacgcagua aucucagucc      600

cagccgaguu cgaccuuaaa caaaggaacu ccaccaucga agcagcuaac cucgccggcc      660

ugaaaauccu ccgagucauc aacgaaccca ccgccgcggc cauggcauac ggacuucaca      720

aagccgacgu cuuccacguc cucguaaucg accugggcgg cggcacccua gacgucagcc      780

uucucaacaa acagggaggc auguuccuca cacgcgcgau gucaggaaac aacaaacuag      840

gaggccagga cuucaaccaa cgccuacucc aauaccuaua caaacaaaua uaccaaaccu      900

acggauucgu uccaucccga aaagaagaaa uccacagacu ccgacaagca guagaaaugg      960

uaaaacucaa ccuaacccua caccaauccg cacaacuaag cguccuccuu acaguagaag     1020

aacaagaccg aaaagaacca cacuccuccg acaccgaacu ccccaaggau aagcuaucca     1080

gcgcugacga ccacagagua aacuccgguu ucggccgugg ccucagcgac aagaaaucug     1140

gugaaucaca gguccuauuc gaaaccgaga uaucccgaaa acucuucgac acccucaacg     1200

aagaccucuu ccagaaaauc cucgucccca uccaacaagu ccucaaagaa ggccaccucg     1260

agaaaacaga aaucgacgaa gucguacucg uaggaggcuc cacacgcauc ccccgcaucc     1320

gacaaguaau ccaagaguuc uucggcaaag accccaacac cucaguagac ccugaccugg     1380

ccgucguaac cggagucgcc auccaggccg gaauugaugg cggauccugg ccccuacaag     1440

ugagcgcccu cgaaauccca aacaaacacc uccagaaaac aaacuuuaac ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4698
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt9)

<400>  4698
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgcaauag gcguccaccu aggcugcacc agcgccugcg      120

ucgccgucua caaagacggc agagcaggcg uagucgccaa cgacgccgga gaccgcguca      180

ccccagcagu cgucgccuac agcgagaacg aagaaaucgu ggggcucgca gccaaacaau      240

cccgcauccg aaauaucucc aacacaguca ugaaaguaaa acaaauccua ggacgcaguu      300

cgucagaucc ccaggcccaa aaauacauag ccgaaucaaa augccuagua auagagaaaa      360

acggcaaacu ccgauacgaa aucgacaccg gugaagaaac aaaauucgua aacccagaag      420

acgucgcacg ccuaauauuc agcaagauga aagaaaccgc ccacucugug cucggaagug      480

acgccaacga cguagucauc accguaccau ucgacuucgg cgaaaaacag aaaaacgccc      540

uaggcgaagc cgcaagagcc gccgguuuca acguccugcg acucauacac gaaccaagcg      600

ccgcgcuccu cgccuacggc aucggccaag acuccccaac cgggaagucc aacauccuag      660

uauucaagcu aggaggcacc agucuauccc uauccgucau ggaagucaac agcggcauau      720

accgcguacu cucaaccaac acagacgaca acaucggcgg agcccauuuc accgaaacac      780

uagcccaaua ccucgccucc gaguuccaac gcucuuucaa acacgacguc cgcggcaacg      840

cgcgcgccau gaugaaacua accaacagcg ccgaaguagc uaaacacuca cucucaacac      900

ucggcuccgc aaacugcuuu cuugacagcc uauacgaagg ccaagacuuc gacugcaacg      960

ucucaagagc cagguucgaa cuacuaugcu caccacucuu caacaaaugc aucgaagcca     1020

uacguggacu acucgaccaa aacggauuca cugccgacga caucaauaaa guaguacucu     1080

gcggaggauc uucacgaaua ccuaaacuac aacaacucau caaagaccuc uucccagccg     1140

ucgaacuucu uaacuccauc ccacccgacg aagucauccc caucggcgcc gccaucgaag     1200

ccggcauccu caucggaaaa gaaaaccuac uuguagagga cucccucaug aucgaaugcu     1260

ccgccagaga cauccuaguc aaaggcguag acgagagcgg cgccagccga uucaccgucc     1320

uauuccccuc cggaacacca cuaccagccc gacgccaaca cacacuacaa gccccaggau     1380

caauauccuc cgucugccuc gaacucuacg aaagcgacgg caaaaacucc gcaaaagaag     1440

aaaccaaauu cgcacaaguc guccuccaag accucgacaa gaaagaaaac ggccuccgcg     1500

acaucuuagc agugcucacc augaaacgcg acggcagccu gcacguaaca ugcacagacc     1560

aggaaaccgg caaaugcgaa gccaucucca uagaaaucgc cucauaagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  4699
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt9)

<400>  4699
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguaguag gacucgacgu agggagccaa uccugcuaca      120

uagccgucgc ccgcgccggu ggcaucgaaa ccaucgcaaa cgaguucagu gaccgaugca      180

cccccuccgu aauauccuuc ggaagcaaaa acagaaccau aggcguagcu gcuaaaaauc      240

agcaaaucac acacgcgaau aacacggucu caaacuucaa acgauuccac ggcagagccu      300

ucaaugaccc cuucauccaa aaagaaaaag aaaaccuauc auacgaccua guaccccuca      360

aaaacggagg cguaggaauc aaagucaugu acaugggaga agaacaccua uucagcguag      420

aacaaauaac ugccaugcua cucaccaaac ucaaggaaac cgcagaaaac ucacugaaaa      480

agccagucac cgacugcgug auaagcgucc ccucuuucuu caccgacgcc gaacgccgau      540

cgguccuaga cgcagcccaa auagucggcc uaaacugucu acgacuaaug aacgacauga      600

cagcaguggc ccugaacuac ggcaucuaua agcaagaccu gcccucgcuc gacgaaaaac      660

cacgcaucgu aguauucguc gauaugggcc acucagcauu ccaaguguca gccugcgcau      720

ucaacaaggg caaacucaaa gugcuaggca ccgccuucga ccccuuucuc ggaggcaaaa      780

acuucgacga aaagcuagug gaacacuucu gcgcagaauu uaaaaccaaa uauaaacucg      840

acgccaaauc caaaaucaga gcccugcuac gacucuacca agaaugcgaa aaacuaaaga      900

aacugauguc cuccaacuca accgaccugc cccugaacau cgaaugcuuc augaacgaca      960

aagacgucuc cgggaaaaug aacagaucac aauucgaaga acuuugcgcc gaacuacucc     1020

agaaaaucga aguaccacuc uacucccucc uggaacaaac ccaccuaaaa gucgaagacg     1080

uguccgccgu agaaauuguc ggcggcgcaa cacgcauacc ggccguaaaa gaacgaauag     1140

cgaaauucuu cggcaaagac aucuccacca cccuuaacgc agacgaagcc gucgcacgcg     1200

gcugcgcccu ccagugcgca auacucucgc cggccuucaa aguccgcgag uucuccguca     1260

cggaugccgu cccauucccg aucucccuga uuuggaacca cgacagcgaa gacacugaag     1320

gaguccauga gguauucagc cgaaaccacg cagcucccuu cagcaaagua cucacauucc     1380

uacgccgcgg accauucgaa cuggaagcgu ucuacaguga cccccaggga guaccguacc     1440

cggaagcaaa aaucggacgc uucguggugc aaaacguauc agcacaaaag gacggcgaga     1500

aaagccgcgu caaaguaaaa guaagaguaa auacgcacgg aaucuucaca aucucaacag     1560

ccucaauggu cgaaaaagua cccaccgagg aaaacgaaau gagcuccgaa gccgauaugg     1620

aaugccucaa ccaacgccca cccgaaaacc ccgauacaga caagaacguc caacaagaca     1680

auuccgaagc gggcacacaa ccccaggucc aaacagacgc acagcaaaca agccaguccc     1740

cacccucacc cgagcucacc ucggaagaga acaaaauacc cgaugccgac aaagcuaacg     1800

agaaaaaggu ggaccaacca cccgaagcca agaaacccaa aaucaaaguc guuaacguag     1860

aacuaccaau agaagccaau cuuguauggc agcucgggaa agaccuccug aauauguaca     1920

ucgaaacaga aggcaaaaug aucaugcagg acaaacucga aaaagaacga aacgaugcca     1980

aaaacgccgu cgaagaauac guauacgagu uccgagacaa acuaugcggc cccuacgaaa     2040

aguucaucug cgaacaagac caucaaaacu uccuccgacu ccucaccgaa acagaagacu     2100

ggcuauacga agaaggcgaa gaccaagcca agcaggcgua cguagacaaa cuagaggaac     2160

uaaugaaaau cgggaccccu guaaaaguac gauuccaaga agccgaagaa cgaccaaaaa     2220

uguuugaaga acugggacag cgccuccagc acuacgccaa gaucgccgca gacuuccgca     2280

auaaagacga aaaauacaac cauauagacg aaagcgaaau gaaaaagguc gaaaagagcg     2340

ucaacgaggu cauggaaugg augaacaacg ucaugaacgc ucaagccaag aaaagucuag     2400

accaagaccc cguagugagg gcgcaagaaa ucaaaaccaa aauaaaagag cugaacaaca     2460

caugugaacc agucgucacg caaccgaaac caaaaaucga aagcccgaaa cucgagcgca     2520

cacccaacgg acccaacauc gacaagaaag aagaagaccu agaagacaaa aacaacuucg     2580

gugccgagcc cccgcaccaa aacggugaau gcuaucccaa cgagaaaaac agcgugaaca     2640

uggaccuuga cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  4700
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt9)

<400>  4700
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagacaaag ugagacgaca acguccgcgu cggcggguuu      120

gcugggcacu cguggcaguc cuccuagcag acuugcucgc ccuaagcgau acccuagcag      180

ugaugucugu agacuuagga ucggaaucga ugaaaguagc caucgucaaa ccgggagugc      240

caauggaaau cguacuaaac aaagaaucac gcaggaaaac ccccgugauc gucacgcuga      300

aagagaauga gcgauucuuc ggcgauuccg cagcauccau ggcgaucaaa aacccgaagg      360

caacacugag auacuuucag caccuccucg gaaaacaggc agacaaccca cacguagccc      420

ucuaccaagc acgcuucccc gagcacgaac uaacauucga cccccaacgc caaaccgugc      480

acuuccaaau cagcagucag cuccaauuua gcccagaaga gguacucgga augguacuca      540

acuacuccag gagccucgcu gaagauuuug ccgaacagcc cauaaaagac gcagucauaa      600

caguacccgu cuucuucaac caagccgaaa gacgagcggu acuccaagca gcaagaaugg      660

ccggccucaa gguccuucaa cugaucaacg acaacacagc gacagcacuc uccuacggag      720

uauucagaag aaaagacaua aacaccacag cacagaacau cauguucuac gacaugggaa      780

gcggaaguac uguuugcaca auaguaaccu accaaauggu aaagaccaaa gaggcaggaa      840

ugcaaccaca acuucaaaua cgaggggucg gcuuugacag gacucuagga ggacuggaga      900

uggaacuccg gcuucgagaa cgccuagcag gacucuucaa cgaacaacga aagggccaga      960

gagccaaaga cguacgagaa aauccacgag caauggccaa acuccuaaga gaagcgaacc     1020

gacucaaaac gguccuaagc gcaaacgcgg accacauggc ccaaaucgaa ggacuaaugg     1080

acgacguuga cuucaaagcc aaaguaacac gaguagaguu ugaagaacuc ugcgccgacc     1140

ucuucgaacg agugccagga ccgguacaac aagcacucca gagcgcagaa augucccuag     1200

acgaaaucga gcaagugauc cuaguaggag gcgcaacccg gguaccacgc guacaagaag     1260

uauuacugaa agcgguggga aaagaagagu uagggaaaaa cauaaacgcc gacgaagccg     1320

cagcaauggg agcaguauac caagccgcgg cccucagcaa agccuucaaa guaaaacccu     1380

ucguagugcg ggacgcaguc guauacccaa uacuggugga guuuaccaga gaagucgaag     1440

aggaacccgg cauccacagc cuaaaacaca acaaaagagu ccuguucucc aggaugggac     1500

ccuacccaca acgcaaggug auaacauuca accgauacag ucacgacuuu aacuuccaca     1560

uaaacuaugg ggaccugggc uuccuaggac ccgaggaccu ccgcgucuuc ggaucccaaa     1620

accuaacaac cguaaaacuc aaaggaguag gagacucuuu caaaaaguac cccgacuacg     1680

aaucaaaggg gauaaaagcc cacuuuaacc ucgacgaaag ugggguccuc agccuggacc     1740

gcguagaguc ggucuucgaa acacucgucg aagacagugc cgaagaagaa ucaacccuaa     1800

cgaaacuagg caacacaaua ucaagccucu ucggaggagg cacaacaccu gacgccaaag     1860

aaaacggaac agacaccgua caagaagaag aggaaagccc cgcggaggga ucaaaagacg     1920

aaccaggcga acagguggaa cucaaagaag aagcggaagc cccagucgag gauggaagcc     1980

aacccccacc acccgaaccg aaaggcgacg caacaccgga aggcgaaaag gccaccgaga     2040

aagaaaacgg ggacaaguca gaagcccaaa agccaaguga aaaagccgaa gcaggcccag     2100

aaggaguagc cccggcccca gaaggagaga aaaagcagaa acccgccagg aaacgccgaa     2160

ugguggagga gauaggcguc gaacucguag uacuggaucu accagaccuc cccgaagaua     2220

agcuagcaca aagcgugcaa aaacuccagg accucacccu gcgcgacuua gaaaaacaag     2280

agagagagaa agcagcaaac agccuggagg ccuucaucuu cgaaacacaa gacaagcugu     2340

accagcccga auaccaagaa gugagcacgg aagaacaaag agaagagauc uccggcaagc     2400

uauccgcagc cagcacgugg cucgaagacg aaggaguagg ggccacaaca guuaugcuca     2460

aagaaaaauu agcagaacua agaaagcuau gccaaggacu auuuuucaga guggaagaga     2520

gaaagaaaug gccggaaagg cucagugccc ucgacaaccu acucaaccau uccagcaugu     2580

uccugaaggg cgcaaggcua auaccagaaa uggaccaaau auucacagaa guagaaauga     2640

ccacucucga gaaaguaaua aacgagacau gggcguggaa aaacgcaacc cucgcagaac     2700

aagcgaagcu gccagccacg gagaagccgg uucuacucag caaggauaua gaagcaaaga     2760

ugauggcacu agacagagaa guccaguacc uguuaaacaa agcaaaauuc acaaaaccac     2820

gcccaaggcc gaaagacaaa aacggaacac gagcagaacc accacugaac gcgucagcuu     2880

cagaccaagg agaaaaagua auacccccag cagggcaaac cgaggacgca gaaccaauca     2940

gugaaccaga gaaaguugag acgggaagcg aaccaggaga cacggaaccc uuagaauuag     3000

gaggcccagg cgcagaacca gaacaaaaag agcaaagcac uggccaaaag cguccccuca     3060

aaaacgacga gcuaugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4701
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt9)

<400>  4701
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaagaga cgcaaacgca agaucaaccg auggaggagg      120

aagaagugga aaccuucgcg uuccaggcag aaaucgcgca acugaugagc cucauaauca      180

acacguuuua cagcaacaaa gaaauauucc ugcgcgagcu aauaagcaac agcagcgacg      240

cacucgacaa gauacguuac gaaucccuaa cggacccgag caaacuagac agcgggaagg      300

aacuacacau caaccucauc cccaacaagc aggaccgaac ccugaccaua gucgacaccg      360

gaauagggau gacgaaagca gaccucauca acaaccucgg aacgaucgcc aaaagcggca      420

cgaaggcuuu cauggaagca cuacaagcgg gcgccgacau aaguaugaua ggccaauucg      480

gaguaggauu cuacagugcc uaccuagugg cagagaaagu caccguaaua acaaaacaca      540

acgacgacga acaauacgcc ugggaaagca gcgccggggg cuccuuuaca guaagaacag      600

acaccggaga accaaugggc cgcggaacaa aaguaauacu ccaccuaaaa gaggaccaaa      660

cagaauaccu cgaggaaaga cgaauaaagg agaucgucaa aaagcacagc caauucauag      720

gauacccaau aacgcuauuc guggaaaaag aacgagacaa agaaguguca gacgacgaag      780

cggaggaaaa agaggauaag gaagaagaga aagagaaaga agaaaaagaa agcgaagaca      840

agccagaaau cgaggacgua gggucggacg aagaggagga aaagaaagac ggcgauaaga      900

aaaagaaaaa gaaaaucaaa gaaaaguaca ucgaccaaga ggagcuaaac aaaacaaaac      960

cgaucuggac acgaaaccca gacgacauca cgaacgagga auacggcgag uucuacaaau     1020

cacucacaaa cgacugggaa gaccaucuag caguaaagca cuucagcguc gaaggccaac     1080

uggaguucag agcucuccug uucguaccca ggcgcgcccc cuucgaccuc uucgaaaaca     1140

gaaagaagaa aaacaacaua aaauuauacg uaagacgagu auucauaaug gacaacugcg     1200

aagaacugau cccggaauac cucaauuuca uccgcggagu cguagacagc gaggaccuac     1260

cacuaaacau aagcagagag augcuacagc agaguaaaau ccuaaaagua auacggaaaa     1320

accuugucaa aaagugccug gagcuauuca ccgaacuugc agaggacaaa gaaaacuaca     1380

agaaguucua cgagcaguuc agcaagaaua uaaaacuagg cauacacgaa gacucacaga     1440

accgcaagaa acuaagcgaa cuccugagau acuacaccag cgccagcggg gacgagaugg     1500

ucagccuaaa agacuacugc acaagaauga aagaaaacca aaaacacauc uacuauauca     1560

cgggagaaac aaaagaccag gucgcgaacu cagccuucgu cgagcgacuc cgcaaacacg     1620

ggcucgaagu aaucuauaug auagagccca uugacgagua cugcguacag caacuaaaag     1680

aguucgaagg aaaaacccuc guaagcguca cgaaagaagg ccuagaacug cccgaagacg     1740

aagaggagaa aaagaaacaa gaagaaaaga aaacaaaauu cgaaaaccug ugcaaaauca     1800

ugaaagacau ccuggagaag aaaguggaga aaguagucgu aagcaaccgc cuaguaacga     1860

gcccaugcug cauagucaca agcacauacg gauggacggc gaacauggag cgaauaauga     1920

aagcccaagc ccugcgagac aacagcacaa ugggauacau ggcggccaaa aagcaccuag     1980

aaaucaaccc cgaccacucc aucaucgaaa cacucagaca aaaagccgaa gccgacaaaa     2040

acgacaaaag cguaaaggac cuggugauac uccuuuacga aaccgcccug cucucaagcg     2100

gcuucucccu ggaggaccca cagacccacg cgaacagaau cuacagaaug auaaagcugg     2160

gccuaggaau agacgaagac gacccaacag ccgacgacac auccgcagcc gucaccgaag     2220

aaaugccacc ccuagaaggg gacgacgaca caagcagaau ggaagaagua gacuaaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  4702
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt9)

<400>  4702
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucaucaa aacuagacuc cggcaaaggc cuacacauaa      120

accucguccc caacaaacaa aaccaaaccc ucaccaucgu agacacacgc aucggcauga      180

ccaaaaccga ccucaucaac aaccucggaa ccgucaccaa auccggcaca aaagccuuca      240

uggaagcccu ccaagcagac gcagacauau ccaugaucgg ccacuucgga guaggcuucu      300

acuccgccua ccucgucgcc aaaaaaguca ccgucaucuc aaaacacaac aacgacgaac      360

aauacaccug ggaauccucc gcaggaggca gcuucaccgu ccgcaccgac gaauaaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  4703
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt9)

<400>  4703
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaag uacaccacgg agaagaggaa gucgaaaccu      120

ucgccuucca agcggaaauc gcccaacuaa ugagcuugau aauaaacacg uucuacucca      180

acaaagagau auuccugcgg gagcuaauau cgaacgccag cgacgcccua gacaagauca      240

gguacgaguc ccucaccgac cccagcaaac uagacucggg caaggaacug aaaaucgaca      300

uaaucccgaa cccgcaagag cgcacccuca cccuagugga cacgggaaua ggcaugacca      360

aagcagaccu cauaaacaac cucggcacca uagccaagag cggaaccaag gccuucaugg      420

aagcacugca agcaggagca gacauaagua ugaucgggca auuuggcgua ggguucuacu      480

cagcguaccu cgucgccgaa aaaguaguag ucauaacgaa acacaacgac gacgagcaau      540

acgcguggga gucaagcgca ggagggagcu ucaccguacg ggcagaccau ggcgaaccca      600

uaggcagagg caccaaagua auccuccacc uaaaggaaga ccaaacagag uaccuagaag      660

aacggagagu aaaagaaguc gucaagaaac acucccaauu cauaggcuau cccaucacac      720

uauaccucga gaaagaacga gaaaaagaaa uauccgacga cgaagccgaa gaagaaaaag      780

gggaaaaaga agaggaagac aaagacgacg aagaaaagcc caaaauagaa gacguuggcu      840

cggacgagga ggacgacagc ggcaaagaca agaaaaagaa aacgaagaaa auaaaagaga      900

aauacaucga ucaagaagaa cucaacaaaa ccaaaccgau cuggacacgg aaccccgacg      960

auaucacgca agaggaguac ggcgaguucu acaaaucacu aacgaacgac ugggaagacc     1020

accucgcggu caagcacuuc aguguggaag gccaacuaga guuccgagcg cuauuguuca     1080

ucccaagacg cgcacccuuc gaccucuucg aaaacaaaaa gaagaaaaau aacauaaaac     1140

uguacguacg acggguguuc aucauggaca gcugcgacga auugauaccg gaauaccuga     1200

acuucauccg aggagucgug gacucagaag accucccacu aaacaucucc cgagaaaugc     1260

uucaacagag caaaauccua aaagugauca ggaaaaacau cguaaagaaa ugcuuagaac     1320

uauucagcga acuagcagag gacaaagaaa acuacaagaa auucuacgaa gccuucagca     1380

aaaacuugaa acuaggcaua cacgaagaca gcacgaaccg aaggcgcuug uccgaacuac     1440

uacgcuacca cacgucccag agcggcgacg agaugaccag ccugagugaa uacgugagcc     1500

gcaugaaaga aacgcagaaa agcauauacu acauaacagg cgaaagcaaa gaacaaguag     1560

cgaacagugc cuuugucgaa agaguacgaa aacgcggauu cgaggucgua uacaugacgg     1620

aaccaauaga ugaguacugc guccaacaac uaaaagaguu cgacgggaaa agccuaguca     1680

guguuacgaa agagggccuc gaacuacccg aagacgagga ggagaaaaag aaaauggaag     1740

aaagcaaagc aaaauucgaa aaccugugca agcucaugaa agaaauauug gacaagaaag     1800

ucgaaaaagu aacgaucucg aaucgacucg uaucaucccc cugcugcaua gucacgagca     1860

cauacggaug gacagcgaau auggagcgga ucaugaaggc acaagcccua cgcgacaaca     1920

gcaccauggg cuacaugaug gcgaagaaac accucgagau aaacccagac cacccgaucg     1980

uggagacgcu aagacagaaa gcagaagccg acaaaaacga caaagccgua aaagaccuag     2040

uaguacugcu auucgaaaca gcccugcuca gcagcggauu cucacucgaa gacccgcaaa     2100

cccacagcaa ccgaaucuac cgcaugauca agcucggacu cggcaucgac gaagacgaag     2160

uagccgccga agaaccgaac gcagccgucc cugacgagau accgccccuc gaaggcgacg     2220

aggacgcaag ccgaauggag gaaguagacu aaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  4704
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt9)

<400>  4704
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgagccuuau ggguccucgg acucugcugc gugcuacuga      120

ccuucggcag cguaagagca gacgacgagg ucgacguaga cggcacggua gaggaagacc      180

ucggcaaauc gcgagaaggc ucacgcacag acgacgaagu aguccagcga gaagaagaag      240

cgauacaacu ugacgggcug aacgcgagcc agauccgcga acucagggag aaaagugaaa      300

aauucgcauu ucaggcagaa guuaacagga ugaugaagcu aaucauaaau ucccuguaca      360

aaaacaaaga gaucuuccua cgggaacuaa uaucaaacgc cagcgacgcu cuagacaaaa      420

ucagacuaau aagccuaaca gacgaaaacg cacuaagcgg aaacgaagaa uugacaguca      480

aaaucaagug cgacaaagag aaaaaccugc ugcacgucac cgacacaggc gugggcauga      540

cccgagagga acucgucaaa aaccugggaa cgauagcaaa gucagggacc agcgaguucc      600

ucaacaaaau gacagaagcc caggaggacg ggcagagcac gagcgaacug auagggcaau      660

ucggaguagg auucuacagc gcguuccugg uagcggacaa agucauaguc accagcaaac      720

acaacaacga uacccagcac aucugggaga gcgacaguaa cgaauuuagc guaaucgcag      780

acccucgagg caacacacua gggcgaggga ccacaauaac acugguacua aaggaagaag      840

ccagugacua ccucgagcua gauaccauca agaaucucgu aaagaaauac ucacaauuca      900

ucaacuuccc aaucuacguc uggagcagca aaacagaaac gguugaagaa ccuauggagg      960

aagaggaagc ggcaaaagag gaaaaggaag aaucagacga cgaggccgcc guggaagagg     1020

aagaagagga aaagaaacca aaaacgaaga aaguggagaa aacaguaugg gacugggaac     1080

ugaugaacga caucaagccc auauggcaaa gaccaagcaa ggaaguagaa gaagacgagu     1140

acaaggcguu cuacaaaagu uucuccaagg agucagacga ccccauggca uauauacacu     1200

ucacggcaga gggcgaaguc acauucaaga gcauacucuu cgugcccacc ucggcaccac     1260

gcggacuauu cgaugaguac gggagcaaga aaagcgacua cauaaaacua uacgucagga     1320

ggguauucau aacggacgac uuccacgaca ugaugcccaa guaccugaac uucgucaagg     1380

gaguagucga uagcgaugac cuaccccuga acguaagcag ggaaacccua caacaacaca     1440

aacuucucaa aguaauccgg aaaaagcucg ugaggaagac ccuagacaug auaaagaaaa     1500

uagcggacga caaauacaac gacacauucu ggaaagaguu cgggacaaac auaaaacuag     1560

gugugauaga ggaccacagc aacaggacga gacuggccaa acuccuacga uuccaaucaa     1620

gccaucaccc cacagacauc acgagccuag accaguacgu agaaagaaug aaggaaaaac     1680

aggacaaaau uuacuucaug gcagggucca gcagaaaaga ggccgaaagc ucccccuucg     1740

ucgaaaggcu gcucaagaaa ggguaugaag ucauauaccu aacagagcca gucgaugaau     1800

acugcauaca ggcacugcca gaguuugacg gcaagagauu ccaaaacguc gcaaaagaag     1860

gagugaaauu cgacgaaagu gagaagacca aagagagcag agaagccguc gagaaagagu     1920

ucgaaccucu ccucaacugg augaaagaca aagcgcuaaa agacaagaua gaaaaagcag     1980

ucguaagcca acgacucaca gaaagcccau gcgcgcuagu cgccucgcaa uacggauggu     2040

cagggaacau ggaaagaauc augaaagcgc aagcguacca aacugggaaa gacauaucca     2100

cgaacuacua cgccagccaa aagaaaacgu ucgaaaucaa ccccaggcau ccacugauaa     2160

gggauaugcu acgcagaaua aaagaagacg aggacgacaa aacaguccuc gaccucgcag     2220

ucguccucuu cgaaacggca acccuuagaa gcggcuaccu gcugccagac accaaagccu     2280

acggagacag gaucgagcga augcuacgac ucucacuaaa cauagacccg gacgcaaaag     2340

uagaggaaga accggaggag gagccagaag aaacagccga agauacaaca gaggacacgg     2400

aacaagacga agacgaagaa auggacguag guacagacga ggaagaagaa acagccaaag     2460

agagcacagc ggagaaggac gagcuauagg gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  4705
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt9)

<400>  4705
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgagaau uaagagcccu auuacucugg ggacgucguc      120

uccguccccu ccuccgcgca ccagcccuag cagccguacc cggcggcaaa cccauucucu      180

gcccaagaag aaccacugcc cagcuagggc cccgacgaaa ccccgcgugg ucgcuccaag      240

cuggacgacu cuucucaacc caaaccgcag aagacaaaga agaaccccuc cacagcauca      300

uaucuucaac agaauccguc caagguagca cauccaaaca cgaguuccaa gccgaaacca      360

agaaacuguu agauaucguc gcccgcuccc ucuacagcga aaaagaaguc uucauccgcg      420

aacugaucuc aaacgccagc gacgcccuag agaaacuacg ccauaagcua gucucagacg      480

gccaagcacu acccgaaaug gaaauucacc uccaaaccaa cgccgaaaaa ggcaccauaa      540

caauccaaga caccggaauc ggcaugaccc aagaggaacu cguaagcaac cucggcacua      600

ucgcgcgcuc agggucaaaa gcauuccuag acgcuuuaca aaaccaggcc gaggcuucau      660

ccaaaauaau cggccaauuc ggcguaggcu ucuacucagc cuucaugguc gcggaucgcg      720

ucgaagucua cucccgcagc gcagccccag ggagccuagg guaccagugg cucagcgacg      780

gcuccggcgu auucgaaauc gccgaagccu ccggagucag aacaggaacc aaaaucauaa      840

uucaccugaa aucugacugc aaagaguuca gcuccgaagc acgcguucga gacguaguca      900

caaaauacuc caacuucguc uccuucccac ucuaccucaa cggaagacgc augaacaccc      960

uccaggccau cuggaugaug gaccccaagg acguccguga auggcaacac gaagaguucu     1020

accgauacgu ggcacaagcc cacgauaaac cacguuacac ccuacacuac aaaaccgacg     1080

ccccacucaa caucagaagc aucuuuuacg uccccgacau gaaaccguca auguucgacg     1140

ucucccguga acuaggaucc uccgucgcac ucuacucacg caaaguccua auccaaacua     1200

aagccacaga cauccuuccc aaauggcucc gguucauacg cggcgucgug gacucagaag     1260

acaucccccu aaaccucucc cgcgaacuac uccaagaauc cgcgcuaauc cgaaaacuua     1320

gagacguacu acaacaacgg cuaaucaaau ucuucaucga ccagaguaag aaagacgccg     1380

aaaaauacgc uaaauucuuc gaagacuacg gacuauucau gcgagaaggc aucgucaccg     1440

ccaccgaaca agaagucaaa gaagauaucg caaaacuccu acgcuacgag ucuuccgccc     1500

uacccucagg acaacuuacc ucacuaagcg aauacgccag ccgcaugcgc gcgggcacac     1560

ggaauauaua cuaccuaugc gcacccaacc gacaucucgc cgaacacagc ccauacuaug     1620

aagccaugaa gaagaaagac acugaagucc uauucugcuu cgaacaauuu gaugagcuca     1680

cccuacuaca ccuccgggaa uuugacaaaa agaaacuaau auccgucgag accgacaucg     1740

ucguagacca cuacaaagag gaaaaauucg aggaccgcuc cccagcagcc gagugccuaa     1800

gcgaaaaaga aaccgaagaa cuaauggccu ggaugcgcaa cguucuaggc ucaagaguaa     1860

ccaacguaaa aguaacccua cgacucgaca cccaccccgc caugguaacc guacucgaaa     1920

ugggagcagc ccgccacuuc cuacgaaugc aacaacucgc caaaacacag gaggaacgag     1980

cccagcuccu acagccaaca cucgaaauca acccccgaca cgcacucauc aagaaacuca     2040

accaacuccg ggcauccgaa ccaggacucg cccagcuccu aguagaccag aucuaugaaa     2100

acgccaugau cgcugcaggc cuagucgacg acccaagagc aaugguugga cgacuaaacg     2160

aacugcucgu caaagcccuc gagcgccacu aaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  4706
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt9)

<400>  4706
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaaaucu ccucccuacc cacccaacua uucaaaugcu      120

gcuucugcga cuuccuaaaa gucaaaaugc acacaauguc cucaucccac uuauucuacc      180

ucgcacucug ccuccucaca uucaccucau ccgccaccgc aggccccgaa acccuaugcg      240

gcgccgaacu cgucgacgca cuccaauucg ucugcggcga ccgcggcuuc uacuucaaca      300

aacccacagg cuacggcucc uccucaagac gagcacccca aaccggcauc guagacgaau      360

gcuguuuccg aucaugcgac cuucgccgcc ucgaaaugua cugcgcaccc cucaaacccg      420

ccaaaucagc ccgcuccguc cgugcccaac gacacaccga caugcccaaa acccaaaaag      480

aaguccaccu caaaaacgcc ucccgcggcu ccgcaggcaa caaaaacuac cgcauguaag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  4707
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt9)

<400>  4707
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaucccca ugggcaaauc aaugcucguc cuccucaccu      120

uccucgccuu cgccuccugc ugcauagccg ccuaccgacc cuccgaaaca cucugcggcg      180

gagaacucgu cgacacccua caauucgucu gcggcgaccg aggcuucuac uucucccgac      240

ccgccucacg aguaucccgc cgcucccgcg gcaucgucga agaaugcugc uuccgcucau      300

gcgaccucgc ccuccucgaa accuacugcg ccaccccagc caaauccgaa cgagacgucu      360

ccaccccacc cacaguacuu cccgacaacu uuccccgaua ccccguaggc aaauucuucc      420

aauacgacac cuggaaacaa ucaacccaac gacuccgccg uggccucccc gcccuacucc      480

gcgcacgccg cggacacguc cuagcaaaag aacucgaagc cuuccgcgaa gccaaacgac      540

accgcccccu caucgcccuc cccacccaag accccgccca cggaggcgcc ccacccgaaa      600

uggccuccaa ccguaaauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  4708
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt9)

<400>  4708
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccaccuccgc cuucggcccc gucgccuucu      120

cccucggccu ccuccucguc cuccccgccg ccuuccccgc ccccgucccc cccggcgaag      180

acuccaaaga cgucgcugcc ccccaccgcc aaccccuaac cuccuccgaa cgcaucgaca      240

aacaaauccg cuacauccua gacggcaucu cugcacuccg aaaagaaacc ugcaacaaau      300

cuaacaugug cgaauccucc aaagaagccc uagccgaaaa caaccucaac uuacccaaaa      360

uggccgaaaa agacggcugc uuccaauccg gcuucaacga agaaaccugc cucgucaaaa      420

ucaucaccgg ccuccucgaa uucgaagucu accucgaaua ccuacaaaac cgauucgaau      480

ccucagaaga acaagcccga gccguccaaa uguccaccaa aguccucauc caauuccucc      540

aaaaaaaagc caaaaaccuc gacgccauca ccacaccuga cccaaccacc aacgccucac      600

uccucacaaa acuccaagcc caaaaccaau ggcuccaaga caugacaaca caccucaucc      660

uccgcuccuu caaagaauuc cuucaauccu cccucagagc ccuccgccaa auguaaggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  4709
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt9)

<400>  4709
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuacucu ggcuacgcgg cuuccuacua gcaagcugcu      120

ggaucauagu aagaagcuca cccaccccag gaagcgaagg acacagcgcc gcgccagacu      180

gcccaucaug cgcacucgcc gcccucccca aagacguacc caacagccag cccgaaaugg      240

uagaagcagu gaaaaaacac auacuaaaca ugcuccaccu aaaaaagcga cccgacguaa      300

cccaacccgu cccaaaagca gcacuacuaa acgcaaucag aaaacuccac guagggaaag      360

ucggcgaaaa cggauacgua gaaaucgaag acgacauagg aaggcgcgcc gaaaugaacg      420

aacucaugga acaaacgucg gaaauaauca cauucgcaga aucagguacg gccagaaaaa      480

cccuacacuu ugagaucagc aaagaaggga gcgaccuaag cgucgucgaa agagcagagg      540

ucuggcuguu ccucaaaguu ccaaaagcca acagaacacg cacaaaagua acaauacgcc      600

uauuccagca acaaaaacac ccacaaggca gccuagacac cggagaagag gccgaggaag      660

uaggacuaaa aggagaacgg agcgaacuac uacuaagcga aaaagucgua gacgcccgca      720

aaagcacaug gcauguauuc cccguaagca gcuccauaca acgacuccua gaccaaggca      780

aaucaucacu cgacguaaga aucgcgugcg aacaaugcca agaaagcgga gccagccuug      840

uacuacuggg caagaaaaaa aaaaaagaag aggaaggcga agggaaaaaa aaaggcggcg      900

gagaaggagg cgccggagca gacgaagaaa aagaacaaag ccacagaccc uuccuaaugc      960

ugcaagcacg acagagcgaa gaccaccccc accgcagacg ccgacgcgga cucgaaugcg     1020

acggaaaagu aaacaucugc ugcaagaaac aauucuucgu cagcuucaag gacauaggau     1080

ggaacgacug gauaauagca ccgagcggcu accaugcaaa cuacugcgaa ggcgaaugcc     1140

caagccacau cgcaggcaca agcggaagca gccuaagcuu ccacagcacc gucaucaacc     1200

acuacagaau gcgaggacac agcccauucg ccaaccugaa aagcugcugc gucccgacga     1260

aacuaagacc aaugagcaug cuauacuacg acgacggcca aaacauaaua aagaaagaca     1320

uacaaaacau gauaguagaa gagugcggcu gcagcuaagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  4710
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt9)

<400>  4710
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccucc ccggccgagc acuaggcgcc gcaugccucc      120

uccuacucgc agccggaugg cuuggccccg aagcaugggg cuccccaaca ccaccuccca      180

cccccgcagc accaccccca cccccaccac ccggcucccc cggcggcagc caggacacau      240

gcaccucaug cggcggcuuc cgacgccccg aagaacucgg ccgcgucgac ggagacuucc      300

ucgaagccgu aaaacgccac auccuuuccc gccuccaaau gcgaggccga cccaacauca      360

cucaugccgu ccccaaagcc gccaugguca ccgcccuacg caaacuccac gccggcaaag      420

uccgagaaga cggccgcguc gaaauccccc accucgacgg ccacgccagc cccggcgccg      480

acggccaaga acgaguuucc gaaaucaucu ccuucgccga aaccgacggc cuugcaucca      540

gccgaguacg ccucuacuuc uucaucucaa acgaaggcaa ccaaaaccuc uucguaguac      600

aagccucccu uuggcucuau cucaaacucc uacccuacgu acuagaaaaa ggcucucgcc      660

gcaaaguaag agucaaaguc uacuuccaag aacaaggcca cggcgaccga uggaacaugg      720

ucgagaaacg cgucgaccua aaacgcuccg guuggcacac auucccccuc accgaagcaa      780

uccaagcccu cuucgaacga ggggaacgcc gccucaaccu agauguccaa ugcgacagcu      840

gccaagaacu agccgucguc cccgucuucg ucgaccccgg cgaggaaucc caccgacccu      900

ucgucgucgu ccaagcacga cucggcgacu cucgccacag aauacguaaa cgaggacucg      960

aaugcgacgg ccgcaccaac cucugcugca gacaacaauu cuucaucgac uuccgccuca     1020

uuggauggaa cgacuggauc auagcaccca cuggauacua cggcaacuac ugcgaaggcu     1080

ccugccccgc auaccucgca ggaguccccg gaagcgcauc cucuuuccac accgcaguag     1140

ugaaccaaua ccgcaugcgc ggccucaacc ccggaaccgu caacagcugc ugcaucccca     1200

ccaaacuuuc caccaugagc augcucuacu ucgacgacga auacaacauc guaaaacgag     1260

acguccccaa caugauagua gaagaaugcg gaugcgcaua aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  4711
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt9)

<400>  4711
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacuaaggg uacuccuccu caccgcccuc acacucugcc      120

acggauucaa ccucgacacu gaaaacgcaa ugacauucca agaaaacgcg cggggcuucg      180

gacaaucagu gguccagcug caagguagcc gcgucgucgu gggcgccccg caagagaucg      240

uagcagccaa ccagcgcggc ucucuauauc aaugcgacua cucaacuggc aguugcgaac      300

ccaucagacu acaaguccca gucgaagcug ucaacaugag ccuuggacua ucgcuagccg      360

caacaaccuc gccuccucaa cuccucgccu gcggcccaac cguccaccag accugcuccg      420

agaauaccua cgucaaaggc cucugcuuuu uguucggcuc uaaccugcgc caacaaccgc      480

aaaaauuccc ggaagcccug cgaggcugcc cccaggaaga cucagacaua gcuuuccuaa      540

uugacggguc cggcuccauc auaccccacg acuuccgucg aaugaaagag uucguaucaa      600

cuguaaugga acaacucaag aaaucuaaaa cgcuguucuc acucaugcaa uacagcgaag      660

aguucaggau ccacuucacc uucaaagagu uccaaaacaa cccaaaccca cgcucgcucg      720

ucaagccaau aacccaacuc cucggcagaa cccauacagc uacaggcauc cgaaaagucg      780

ucagagaacu cuucaacauc accaacggcg cccggaaaaa ugccuucaaa auccuuguag      840

ucaucaccga cggugaaaaa uucggcgauc cucuuggaua cgaagacgua auuccugaag      900

ccgacagaga aggagugauu cgauacguca ucggaguggg cgacgcauuc cgcagugaaa      960

agucccgaca agaacugaac accaucgccu ccaaaccucc ccgagaccac guuuuccaag     1020

uaaacaacuu cgaagcacuc aagaccaucc aaaaccaacu gcgcgagaaa auauucgcaa     1080

ucgaaggcac gcaaaccggg uccaguucau ccuucgaaca cgaaaugucc caggaaggau     1140

uuuccgcagc gaucacuucc aacggacccu uacuauccac agucggcucg uacgacuggg     1200

ccggcggcgu auuccuauac accagcaaag aaaaauccac cuucaucaac augacccggg     1260

ucgacagcga caugaacgau gccuaccucg gguaugcagc cgcaauuaua cuaaggaacc     1320

gcguucaauc ccucguacug ggagcacccc gcuaccagca cauaggccua guggcuaugu     1380

uccgucaaaa cacaggcaug ugggaaucca augccaacgu uaagggcacg caaauaggag     1440

ccuacuucgg cgccucucua ugcuccguag acguagacuc caacggaucc acagaccuag     1500

uacugaucgg cgcaccccac uacuacgaac aaaccagagg cggacaaguc ucaguguguc     1560

cacucccccg cggucgagca cgauggcaau gugaugccgu ccuauacggc gaacagggac     1620

aaccgugggg ccgcuuugga gcugcccuca ccguccucgg cgauguaaac ggugacaaac     1680

ucacugaugu agccauaggc gcccccggag aagaggauaa cagaggagcc gucuaccuau     1740

uccacggcac cucaggaagc gggaucagcc caucccacuc ccaacgcaua gcgggcucaa     1800

agcuaucgcc ucgccugcag uacuuuggcc aaagccucuc cggcggccaa gaccucacca     1860

uggacggucu aguagaccuc acaguaggag cccaaggaca uguacuccuc cuucgcucgc     1920

agcccguacu cagaguaaag gccaucaugg aauuuaaucc aagagaaguc gcccgaaacg     1980

uauucgaaug caacgaucag gugguuaaag guaaagaagc cggugaggua cgcguauguc     2040

uccacguaca aaaaucgacc cgggacagac uucgcgaagg acaaauccaa ucaguaguca     2100

ccuacgaccu cgcucuagac uccggucguc cccauucacg agccguguuc aacgaaacca     2160

aaaacucuac aagacgccaa acucagguac ucggcuugac acaaacuugu gagaccuuaa     2220

aacuucagcu gccaaacugu aucgaggacc ccgucucccc aaucguacug cggcuuaacu     2280

ucucucucgu cggcacaccc cuuuccgcgu ucgguaaccu gagacccguc cucgcagaag     2340

acgcccaacg acucuucacc gcacucuucc ccuuugagaa aaacugcggc aacgacaaca     2400

ucugccaaga ugacuuaagc auuacauucu cauuuaugag ccuagacugu cucguaguag     2460

gcggaccccg ggaauuuaac gucacuguaa ccgugcgcaa cgacggugaa gacuccuaca     2520

ggacgcaagu cacauucuuc uucccccucg acuuaagcua ccguaaaguc agcacccuuc     2580

agaaccagcg uucucaacga uccuggaggc uugcgugcga aucagcuagc ucaaccgagg     2640

ucuccggcgc gcucaaaucc accucaugcu ccaucaacca ccccaucuuc cccgaaaaca     2700

gcgaaguuac cuucaacaua accuucgacg uagacuccaa ggcaucacua ggaaacaaac     2760

uccuccucaa ggccaacgua accuccgaga auaacaugcc acgcacgaau aaaacagagu     2820

uccaauugga acuccccgua aaauacgcgg uauacauggu cgucacuucu cacggaguau     2880

cuaccaaaua ccuaaacuuu acagccuccg aaaacacaag ccgaguaaug cagcaucaau     2940

accaaguguc aaaccuggga caaagaucgc uaccuaucuc acucgucuuc cugguaccgg     3000

ucaggcuuaa ccaaacgguc auaugggacc gcccccaagu aaccuuuuca gaaaaccucu     3060

ccagcacaug ccacaccaaa gaaaggcucc caucacauag cgacuuccua gcagagcucc     3120

gcaaggcgcc cgucguuaac ugcuccauag cagugugcca acgcauccag ugcgacauac     3180

cauucuuugg cauccaggag gaguucaacg caacccucaa gggaaaccuc ucuuucgacu     3240

gguacauaaa aacuucccac aaucaccucc uaaucgucuc caccgcagaa auccucuuca     3300

acgacagcgu auucacccua cuaccaggcc agggagcguu cguccggagc caaaccgaaa     3360

ccaaagugga accauuugaa guacccaacc ccuuaccccu aaucgucggg uccucagucg     3420

gcggccuacu acuucucgcu uuaaucaccg ccgcccucua caaacuaggc uuuuucaaaa     3480

gacaauacaa agacaugaug uccgaaggag gcccacccgg ggccgaaccg caauaaggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  4712
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt9)

<400>  4712
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucagccuca aaacgcuccc cuuccuccua cuccuccacg      120

uccaaauauc uaaagccuuu cccgucuccu cuaaagaaaa gaacacaaaa acaguacaag      180

acuaccugga aaaauucuac caacucccau ccaaccaaua ccagucaacc cgcaaaaacg      240

gcaccaacgu aaucgucgaa aaacucaaag aaaugcaacg cuucuucgga cucaacguca      300

cugguaaacc aaacgaagaa acccucgaca ugaugaaaaa gccgagaugc ggcguaccag      360

acuccggcgg cuuuaugcuc acccccggaa acccgaaaug ggaacgcacc aaccucaccu      420

accgcauacg aaacuacaca ccccaacucu cugaagccga agucgaacgu gccaucaaag      480

acgccuucga acucugguca guagccuccc cacucauuuu cacacgaauc ucccaaggug      540

aagccgacau caacaucgcc uucuaccaac gagaccacgg cgacaauucc cccuuugacg      600

gcccaaacgg aauacuagcc cacgccuucc aacccgguca aggcaucggc ggcgacgccc      660

acuucgacgc agaagaaacc uggaccaaua ccuccgcaaa cuacaaccuc uuccucgucg      720

cagcccacga auuuggacac ucacucggcc ucgcacacuc uagcgacccc ggcgcccuca      780

uguaccccaa cuacgccuuc cgagaaaccu ccaacuacuc acucccgcaa gacgacaucg      840

auggaaucca agccaucuac ggccucuccu ccaacccaau ccaacccacu ggccccucaa      900

cccccaaacc cugugaccca ucccucacau ucgacgccau uaccacccuc cgcggggaaa      960

uccucuucuu caaagaucgc uacuucuggc gccgacaccc ccaacuacaa cgcgucgaaa     1020

ugaauuucau cucccucuuc uggcccuccc ucccuaccgg cauucaagcc gccuacgaag     1080

acuucgaucg cgaccuuauu uuucucuuua aaggcaacca auacugggcc cucucgggcu     1140

acgacauccu acaaggauac cccaaagaca ucuccaacua cggauucccc ucuuccgucc     1200

aagcuauaga cgccgccguc uucuaccgau ccaagacaua cuucuucguc aaugaccaau     1260

ucuggcgaua cgacaaccaa cgacaguuca uggaacccgg guaccccaaa uccauuuccg     1320

gagccuuccc aggcaucgaa uccaaagucg acgccgucuu ccagcaagaa cacuucuucc     1380

acgucuucuc aggcccccgc uacuacgccu ucgaccuaau cgcccaacgc gucacccgcg     1440

ucgcccgagg caacaaaugg cucaacugca gauacggaua aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  4713
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt9)

<400>  4713
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguggc aaccccucgu ccucguccuu cuuguccucg      120

guugcuguuu cgccgcaccc cgccaacgac aguccacccu cguccucuuc cccggagacc      180

uccgcacaaa ccuaacugac cgccagcucg ccgaagaaua ucuuuaccgc uacggcuaca      240

cccgcgucgc agaaaugaga ggcgaaucca aaucucuggg gcccgcccuc cuccuccucc      300

aaaaacagcu cucccucccc gagaccggag aacuugacuc cgccacccuc aaagcaaugc      360

gaacaccacg cugcggcguc ccagaccucg gccgcuucca aacguucgaa ggcgaccuaa      420

aauggcauca ucacaacauu accuacugga uccaaaacua cuccgaagac cucccccgcg      480

ccguaauaga cgacgccuuc gccagagccu ucgcgcucug guccgccguc accccacuaa      540

cauucacccg cgucuacuca cgcgacgccg acauagugau ucaauucggu gucgcugaac      600

acggggacgg cuaccccuuc gacggaaaag acggccuacu ggcccacgca uucccacccg      660

gacccggaau ccaaggugac gcccacuuug acgacgacga gcuuuggucc cuaggaaagg      720

gcgucguagu cccaacacgc uucggaaacg cagacggcgc cgcuugccac uuccccuuca      780

uauucgaagg aagguccuac ucagcaugca ccaccgacgg ccgaucagac ggccucccgu      840

ggugcucgac cacagcgaac uacgacacag augaccgcuu cggcuucugc cccucagaac      900

gacuauacac ccaggacggc aacgccgacg gaaaacccug ccaauuccca uucauauucc      960

agggucagag cuacuccgcc uguacgacgg acggcagaag cgauggcuac cgcuggugcg     1020

caaccacagc gaacuacgac cgagacaaac uuuucgguuu cuguccaacc cgcgcagacu     1080

ccaccguaau gggcggcaac agcgccggag aacuaugcgu cuucccauuc accuuccucg     1140

gaaaagaaua cuccacuugu accucggaag gcagaggcga cggaagacuc uggugugcua     1200

caaccucaaa cuucgacucc gacaagaaau ggggcuucug ccccgaucaa ggcuacaguc     1260

uauuccucgu cgcagcccac gaguucggac acgcccucgg gcucgaccac uccuccguac     1320

ccgaagcgcu aauguaccca auguacaggu uuaccgaagg accaccccua cacaaagacg     1380

acgucaacgg aauccgccac cuuuacggcc cccgccccga acccgaaccu cguccaccca     1440

ccacaacaac accccaaccc accgcaccgc caaccguaug ucccacgggg cccccuaccg     1500

uccacccgag cgaaagaccc acagcaggcc cuaccggucc acccucagca ggacccacag     1560

gacccccuac ugccggcccc ucuacagcca cuacuguccc ccuaagccca guugacgacg     1620

caugcaacgu aaacauauuu gacgcaaucg ccgaaaucgg caaccaacuu uaccuauuca     1680

aagacgguaa auacuggcga uucuccgaag gacgcggaag ucgcccccag ggcccauucc     1740

uaaucgcaga caaauggcca gcccuaccga gaaaacuaga uucagucuuc gaagaaagac     1800

uaagcaagaa acucuucuuc uuuucuggcc gacaaguaug gguauacaca ggagccagcg     1860

uacuaggccc cagaagacuc gacaaacuag gccuaggagc agacguugca caaguaaccg     1920

gagcucuccg uuccggcaga ggcaaaaugc uauuguucuc uggccgcaga cuuuggcgcu     1980

ucgacgucaa agcucaaaug guagaccccc gauccgcauc cgaggucgac cgcauguucc     2040

ccggcguccc cuuagacaca cacgacguuu uccaguaccg agagaaagcc uacuucugcc     2100

aagaccgcuu cuacuggaga guaagcagca gguccgaacu caaccaagua gaccaagucg     2160

gauacguaac auacgacauc cuccaaugcc cagaagacug aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  4714
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt9)

<400>  4714
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggag uccucgccgc auuccuauuc cucuccugga      120

cccacugccg agcccuaccc cucccauccg gcggagacga agaugaccuc uccgaagaag      180

accuccaauu cgcagaacgc uaccuucgcu ccuacuacca cccaaccaau cucgcaggca      240

uccuaaaaga aaacgccgca uccucaauga ccgaacgccu ccgagaaaug caauccuucu      300

ucggccucga agucaccggc aaacucgacg acaacacccu cgacguaaug aaaaaaccua      360

gaugcggagu cccagacguc ggagaauaca acguauuccc ccguacccug aaauggucaa      420

aaaugaaccu cacguacagg aucguaaacu acacccccga caugacccau agcgaagucg      480

aaaaagccuu caaaaaagcc uucaaagucu gguccgacgu cacuccacua aacuucaccc      540

gucuccacga cggcauagcc gacaucauga uauccuucgg aaucaaagag cacggcgacu      600

ucuaccccuu cgacggaccc agcggucucc ucgcacacgc cuuccccccg ggccccaacu      660

acggcggaga cgcccacuuc gaugacgacg agaccuggac auccuccuca aagggcuaca      720

accucuuccu cgucgccgcc cacgaauucg ggcacucacu uggacucgac cauuccaaag      780

accccggagc ccucauguuc ccaaucuaca cauacaccgg caaaagucac uucaugcucc      840

ccgacgacga cguccaagga auucaaagcc ucuacggccc cggcgaugaa gaccccaacc      900

ccaaacaucc caaaacaccc gacaagugcg acccuucccu cagccucgac gcaaucaccu      960

cacucagagg cgaaaccaug auauucaaag accgauucuu cuggcgacuc cacccgcaac     1020

aaguagacgc cgaacuauuc cuaaccaaau ccuucuggcc agaacuaccu aaccgaaucg     1080

acgccgccua cgaacacccc agccacgacc ucaucuucau cuuccgcggc agaaaauucu     1140

gggcccucaa cggcuacgac auccucgaag gcuaccccaa aaaaauaucu gaacucggcc     1200

ucccaaaaga agucaaaaaa auauccgccg ccguccacuu cgaagacacc ggcaaaaccc     1260

uacucuuuag cggcaaccaa gucuggcgau acgacgacac gaaccacauc auggacaaag     1320

acuacccucg ccucaucgaa gaagacuucc caggaaucgg cgauaaagua gacgcgguuu     1380

acgaaaaaaa cggcuacauc uacuucuuca acggcccaau acaauucgaa uacuccauau     1440

gguccaaccg aauagucaga gugaugccag caaauucaau ccucuggugc uaaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4715
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt9)

<400>  4715
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaccccca acacaaccga agacuacgac accaccacgg      120

aguucgacua cggcgacgcc acccccugcc aaaagguaaa cgaacgagcc uucggcgcac      180

aacuucuccc accccuguac ucccuagugu ucguaauagg ccucgucggc aauauccuag      240

ucguauuagu ccucguccaa uacaaacgcc ucaagaacau gaccucuaua uaccuacuca      300

accuagcaau cuccgaccuc cuuuuccugu ucacccuccc cuucuggauc gacuauaaac      360

ucaaagacga uugggucuuc ggagacgcca ugugcaaaau ccucuccggc uucuauuaua      420

ccggucucua cuccgaaauc uucuucauaa uccuccucac caucgacaga uaucucgcca      480

uaguccacgc cgucuuugca cuccgcgccc gcaccgucac cuucgguguc aucaccucca      540

ucauaaucug ggccuuagcc auccucgccu ccaugcccgg acucuacuuu uccaaaaccc      600

aaugggaguu cacccaccau accugcuccc uccacuuccc ccacgaaucc cuacgcgaau      660

ggaaacucuu ccaagcacua aaacuaaacc ucuuuggccu cguccuuccc cuccuaguca      720

ugaucaucug cuacacaggc aucaucaaaa uccuacuucg ucgcccuaau gaaaagaaau      780

ccaaagccgu ccgacucauc uucgucauca ugauaaucuu uuuccucuuc uggacacccu      840

auaaucucac cauccucauc ucugucuucc aagacuuccu cuucacacac gaaugcgaac      900

aaucccgcca ccuagaccuc gccguccaag ucaccgaagu caucgcauac acccacugcu      960

gcgucaaccc cgucauauac gcauucgucg gcgaacgcuu ccgcaaguac cuccgccaac     1020

ucuuccaccg acgcgucgca guccaucucg ucaaaugguu acccuuucuc ucugucgacc     1080

gccucgaacg cguauccuca acaucacccu ccaccggcga acaugaacuu ucagccggcu     1140

ucuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  4716
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt9)

<400>  4716
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgaacccucg ccugccuccu ccuccucggc ugcggcuacc      120

ucgcccacgu acucgccgaa gaagcagaaa ucccccgcga agucaucgaa cgccucgcac      180

gcucccaaau ccacuccauc cgugaccucc aacgacuccu ggaaaucgac uccgucggau      240

ccgaagacuc ccuagacacc ucccuaagag cccacggcgu acacgccaca aaacacgucc      300

ccgaaaaacg accccucccc auccgcagaa aacgauccau agaagaagcc guccccgccg      360

uaugcaaaac acgcacaguc aucuacgaaa uaccccgcuc ccaagucgac ccaaccuccg      420

ccaacuuccu aaucuggccc cccugcgucg aagucaaacg cugcaccggc ugcugcaaca      480

ccuccucagu caaaugccaa cccagccgcg uccaccaccg cagcgucaaa gucgcaaaag      540

ucgaauacgu acgcaaaaaa cccaaacuca aagaagucca agucagacuc gaagaacacc      600

uagaaugcgc augcgccacc accagccuaa acccagacua ccgcgaagaa gacaccggcc      660

gaccccgcga auccggcaaa aaacgcaaac gcaaaagacu aaaacccacc uaaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  4717
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt9)

<400>  4717
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaccgcugcu gggcccuauu ccuaagccua ugcugcuacc      120

uccgccuagu cucggccgag ggcgacccca uccccgaaga acucuacgaa augcucagcg      180

aucacucaau ccgcuccuuc gacgaccucc aacgccuccu ccacggcgac cccggcgaag      240

aagacggagc cgaacuagac cucaacauga cacgcucaca cuccggaggg gaacucgaau      300

cccucgcacg cggccgccgc agccuaggcu cacuaacaau cgccgaacca gcaaugaucg      360

ccgaaugcaa aacaagaaca gaagucuucg aaaucucacg ccgccuaauc gaccgcacca      420

acgccaacuu ccuagucugg ccacccugcg ucgaagucca aagaugcucc ggaugcugca      480

acaacagaaa cguccaaugc cgccccaccc aaguccaacu ccgaccagua caaguaagaa      540

aaauagaaau cguccgcaaa aaacccaucu ucaaaaaagc aaccguaacc cucgaagacc      600

accucgcaug caaaugcgaa accgucgccg cagcccgccc cgucacccgc agccccggcg      660

gaagccaaga acaacgagca aaaacacccc aaaccagagu caccauccga acaguccgcg      720

uacgcagacc ccccaaagga aaacaccgca aauucaaaca cacacacgac aaaaccgccc      780

uaaaagaaac ccuaggcgcc uaaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  4718
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt9)

<400>  4718
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucccucuucg gccuacuccu ccuaacaucu gcacucgccg      120

gccaacgcca aggcacccaa gccgaaucca accucagcuc uaaauuccaa uucuccucaa      180

acaaagaaca aaacggcguc caagaccccc aacacgaacg cauaaucaca gucucaacca      240

acggcuccau ccauucaccc cguuuccccc acaccuaccc ccgcaacacc guccuaguau      300

ggcgccuagu agcaguagag gaaaacgucu ggauccaacu caccuucgac gaacgcuuug      360

gacucgaaga uccagaagac gauaucugca aauacgacuu cgucgaagua gaagaaccuu      420

ccgacggcac aauccuaggc cgauggugcg gcuccggcac cgucccaggc aaacaaauau      480

ccaaaggcaa ccaaauccgc auccgcuucg ucuccgacga auacuucccc uccgaacccg      540

gcuucugcau ccacuacaac aucgucaugc cccaauucac cgaagccguc ucccccuccg      600

uccucccacc cuccgcacuc ccccuagacc ugcucaacaa cgccaucacc gccuucucaa      660

cccucgagga ccucauacgc uaccuagagc ccgaacgcug gcaacucgac cucgaagacc      720

ucuaccgccc aacauggcaa cuccucggca aagccuucgu cuucggccgc aaaucccgcg      780

uagucgaccu aaaccuacua accgaagaag uacgccucua cagcugcaca ccacgcaacu      840

ucucagucuc cauccgcgaa gaacucaaac gcaccgacac caucuucugg ccaggcugcc      900

uccuaguaaa acgcugcggc gggaacugcg ccugcugccu ccacaacugc aacgaaugcc      960

aaugcguccc auccaaaguc accaagaaau accacgaagu gcuacaacua agaccaaaaa     1020

ccggcguccg cggacuccac aaaucucuca ccgacguagc ccuagaacac cacgaagaau     1080

gcgacugcgu cugccgcggc uccaccggcg gcuaaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  4719
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt9)

<400>  4719
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgccuca uauuugucua cacacugaua ugcgccaacu      120

ucuguucaug ccgcgacacc uccgccaccc cccaaucugc cuccauaaaa gcccucagaa      180

acgccaaccu acgacgcgac gaccucuacc gacgcgacga aacaauacaa gucaaaggca      240

acggcuacgu acaaucccca cgcuucccca acuccuaccc ccgcaaccuc cuccucaccu      300

ggcggcuaca cucccaagaa aacacccgca uacagcuugu auucgacaac caauucggcc      360

uagaagaagc cgagaacgac aucugccgau acgacuucgu cgaagucgaa gacaucagcg      420

aaaccuccac caucaucaga ggaagauggu gcggccacaa agaagucccc ccucgaauca      480

aaucccgcac aaaccagaua aaaauaacau ucaaauccga cgacuacuuc gucgccaaac      540

ccggcuucaa aaucuacuac ucccuccucg aagauuucca acccgccgcc gccuccgaaa      600

caaacuggga auccgucacc uccuccauau ccggugucuc auacaacucc ccaagcguca      660

cagacccaac ccucauugca gacgcacuag acaaaaaaau cgccgaauuc gacaccgucg      720

aggaccuccu aaaauacuuc aaccccgaau ccuggcaaga agaccucgaa aacauguacc      780

ucgacacacc ccgcuacaga ggccgcuccu accacgaccg caaauccaag gucgaccucg      840

accgccucaa cgacgacgcc aaacgcuaca gcugcacacc ccgcaauuac agugucaaca      900

ucagagagga acuaaaacua gccaacguag ucuucuuccc acgcugccua cuaguacagc      960

gaugcggcgg caacugcggc ugcggcaccg ugaacuggcg guccugcacc uguaacuccg     1020

gcaaaacagu aaaaaaauau cacgaagucc uacaguuuga acccggacac aucaaacgcc     1080

guggccgcgc caaaacuaug gcccucguug acauccaacu cgaccaccac gaacgcugcg     1140

acugcauaug cucuucccgc ccaccccgau aaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  4720
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt9)

<400>  4720
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccauu caaaauuccc cgccgccggc augucccgcc      120

cccucgacac cucccuccgc cucaaaacau ucuccuccaa auccgaauac caacucgucg      180

ucaacgccgu ccgcaaacuc caagaauccg gcuucuacug gucugccguc accggaggcg      240

aagccaaccu ccuacuauca gccgaaccag cuggcaccuu ccuaauccgu gacuccuccg      300

accaacgcca cuucuucacc cucucaguca aaacccaauc cggcaccaaa aaccuccgca      360

uccaaugcga aggcggaucc uucucccuac aauccgaccc ccgcucaacu caaccagucc      420

cccgauucga cugcguccuc aaacucgucc accacuacau gcccccaccc ggagcccccu      480

ccuuccccuc cccacccacc gaacccuccu ccgaaguccc cgaacaaccc uccgcccaac      540

cccuccccgg aucaccaccc cgccgcgccu acuacaucua cuccggcggc gagaaaaucc      600

cccuaguccu cucccgccca cucucaucca auguugccac ccuacaacac cucugccgua      660

aaaccguaaa cggacaccua gacuccuacg aaaaaguuac ccaacuaccc ggccccaucc      720

gcgaauuucu cgaccaauac gaugcacccc ucuaaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  4721
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt9)

<400>  4721
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guccccuccg ccggccaacu agcccucuuc gcccuaggca      120

ucguccucgc agccugucaa gcacucgaaa acuccaccuc cccccucuca gccgacccac      180

ccguagccgc agccguaguc ucccacuuca acgacugccc cgacucccac acccaauucu      240

gcuuccacgg aaccugccga uuccucgucc aagaagacaa acccgccugc guaugccacu      300

ccggcuacgu cggcgcccgc ugcgaacacg ccgaccuccu agccguagua gccgccucac      360

aaaaaaaaca agccauaacc gcacucguag ucgucuccau cgucgcccuc gccguccuua      420

uaauaaccug cguccucauc cacugcugcc aaguacgcaa acacugcgaa uggugccgcg      480

cccucaucug cagacacgaa aaacccuccg cacuacucaa aggccgcacc gccugcugcc      540

auuccgaaac cguaguauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  4722
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt9)

<400>  4722
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaccauccg gccuacgucu ccucccucuc cuccugccac      120

uccucuggcu auuaguccua acaccaggcc gcccagccgc cggccucuca accugcaaaa      180

cuaucgacau ggaacuuguc aaacgcaaac gaauagaagc cauccgcggc caaauccuau      240

ccaaacuccg ccucgccucc ccacccucac aaggcgaagu accacccgga ccccuacccg      300

aagccguccu ugcacucuau aacuccaccc gcgaccgagu ugcuggagaa ucagccgaac      360

ccgaaccaga gccagaagcc gacuacuacg ccaaagaagu cacccgcgua cucauggucg      420

aaacacacaa cgagauauac gauaaauuca agcaauccac ccacuccaua uacauguucu      480

ucaacaccuc agaacuacga gaagccgucc ccgaacccgu ccuacuauca cgagccgaac      540

uucgucuccu ccgacucaaa cucaaggucg aacaacacgu cgaacucuac caaaaauauu      600

caaacaacuc auggcgcuac cuaucaaacc gccuacuagc accaucagac ucacccgaau      660

ggcuaucauu cgacgucacc ggagucgucc gccaauggcu aucacgagga ggcgaaaucg      720

aaggcuucag acucucagcc cacugcuccu gcgacucccg agacaacacc cuccaagucg      780

acaucaacgg cuucaccacc ggccgacgcg gagaccucgc cacaauacac ggaaugaacc      840

gacccuuccu acuccucaug gcaacaccac ucgaacgcgc ccaacaccuc caaucuuccc      900

gccaccgccg agcccuggac accaacuacu gcuucuccuc cacugagaaa aauugcugcg      960

ugagacaacu cuacaucgac uuccgcaaag accucggcug gaaauggauc cacgaaccaa     1020

aaggcuacca cgcaaacuuc ugccucggcc ccugcccaua cauauggucc cuagacaccc     1080

aauacuccaa aguucuagcc cuauacaacc aacacaaccc cggcgccucc gcggcucccu     1140

gcugcguucc ccaagcccuc gaaccccucc caauagucua cuacgucggc cgcaaaccaa     1200

aagucgaaca acucuccaac augaucgucc gauccugcaa augcuccuaa ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  4723
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt9)

<400>  4723
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uacucucagc cuuccucauc cuccaccucg      120

ucaccgucgc acuaucacua ucuaccugca gcacacucga uauggaccaa uucaugcgca      180

aacgcauaga agcuauccgu ggccaaaucc uauccaaacu caagcucacc agcccacccg      240

aagacuaucc ugaacccgaa gaagucccac ccgaaguaau cuccaucuac aacuccacac      300

gcgaccuccu acaagaaaaa gccucccgac gcgcagccgc cugcgaacga gagcgcuccg      360

acgaagaaua cuacgccaaa gaaguauaca agauagacau gccacccuuc uucccuuccg      420

aaaacgccau acccccaacc uucuaccgcc cauacuuccg caucguccgc uucgacgucu      480

cugcuaugga gaaaaaugca uccaaccucg ucaaagccga guuccgcgua uuccgccuac      540

aaaaccccaa agcgcgcguc ccugaacaac gcaucgaacu cuaccagauc cucaaaucca      600

aagaucuuac cucgcccaca caacgcuaca ucgacuccaa agucguaaag acccgcgccg      660

aaggagaaug gcucuccuuc gacguaaccg acgccgucca cgaauggcua caccacaaag      720

accgcaaccu cggcuucaaa aucucccuac acugccccug cugcaccuuc guccccucca      780

acaauuacau cauccccaau aaauccgaag aacucgaagc cagauucgcc ggcaucgacg      840

gcaccucaac cuacacaucc ggcgaccaga aaaccaucaa aucaacccgc aagaaaaacu      900

ccggcaaaac cccacaucuc cuccucaugc uucucccuuc auaccgucuc gaaucucaac      960

aaaccaaccg acgcaagaaa cgcgcccucg acgccgccua cuguuuccgc aacguccaag     1020

acaacugcug ccuacgaccc cucuacauag acuucaaacg cgaccucggc uggaaaugga     1080

uccacgaacc caaaggcuac aacgcuaacu ucugcgcggg cgccugcccc uaccuauggu     1140

ccuccgacac ccaacacuca cgcguccucu cccucuacaa caccaucaau ccugaagccu     1200

ccgccucacc cugcugcguc ucccaagacc ucgaaccacu caccauacua uacuacaucg     1260

gcaaaacgcc uaaaauagaa caacuaucua acaugaucgu caaauccugu aaaugcagcu     1320

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  4724
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt9)

<400>  4724
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaugcacc uccaacgcgc ccuagucgua cucgcacuac      120

ucaacuuugc caccguauca cuuucacucu ccacaugcac cacacucgac uuuggccaca      180

ucaaaaagaa acgagucgaa gcuauacgag gccaaauccu aucaaaacua cgccucacau      240

ccccacccga acccacagua augacccacg uccccuacca aguacucgcc cuauacaacu      300

ccacccgcga acuccuagaa gaaaugcacg gagaaagaga agaaggaugc acccaggaaa      360

acaccgaauc agaauacuac gccaaagaaa uacacaaauu cgacaugauc caaggccucg      420

ccgaacacaa cgaauuagcc gucugcccca aagguaucac uagcaaagua uuccgauuca      480

acguuuccuc ggucgagaaa aaccgcacca accuauuccg agccgaguuc cguguccucc      540

gcguccccaa cccaagcuca aaacgcaacg aacaacgcau cgaacuuuuc caaauacuaa      600

gacccgacga acacaucgcc aaacaacgcu acauaggcgg caaaaaccuc ccaacccgcg      660

gcaccgcaga auggcucucu uucgacguca ccgacaccgu acgugaaugg cuacucagac      720

gcgaauccaa ccuaggucua gaaaucucaa uacacugccc cugccacacc uuccaaccaa      780

acggagacau ccucgaaaac auccacgaag ucauggaaau caaauucaaa ggagucgaca      840

augaagacga ccacggacga ggcgaccucg gacgacucaa aaagcaaaaa gaccaccaca      900

acccccaccu cauccuaaug augaucccac cccaccgccu cgacaacccc ggacaaggcg      960

gccaacgcaa gaaacgcgcc cucgacacca acuacugcuu ccgcaaccua gaagaaaacu     1020

gcugcguacg cccccucuac aucgacuucc gacaagaccu aggcuggaaa uggguccacg     1080

aacccaaagg auacuacgca aauuucugca gcggaccaug cccauaccua cgguccgccg     1140

acacaaccca cuccacaguc cuaggacuuu auaacacccu aaacccagaa gccuccgccu     1200

cccccugcug ugucccccaa gaccuugaac cucucaccau ccuuuacuac gucggcagaa     1260

cccccaaagu cgaacaacua uccaacaugg ucgucaaauc cugcaaaugc uccuaaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4725
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt9)

<400>  4725
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacccguug cagucugggc agcccuugcc gucggccucg      120

aacucugggc cgcugcccac gcccuccccg cccaaguugc cuucacuccu uacgccccag      180

aaccaggcuc cacaugccga cuccgagaau acuaugacca aacagcccaa augugcugcu      240

ccaagugcuc ccccggccaa cacgccaaag ucuucuguac caaaaccucu gacaccgucu      300

gcgacuccug cgaagacucc acuuacaccc aacuauggaa cuggguaccc gaaugccucu      360

ccugcggcuc cagaugcuca uccgaccaag ucgaaaccca agcaugcaca cgcgaacaaa      420

accgaaucug cacaugcagg cccggauggu acugcgcacu cuccaaacaa gaaggcugcc      480

gccucugcgc accccuccga aaaugccgac caggcuucgg cgucgcccgc ccaggaacag      540

aaaccuccga cguagucugc aaacccugcg ccccuggcac uuucuccaac acaaccagcu      600

caaccgacau augccgccca caccaaaucu gcaacgucgu ugcaauaccc ggcaacgcau      660

ccauggacgc cgucugcacc uccacaucgc ccacccgauc cauggcaccc ggcgccgucc      720

accuccccca accugucuca acccgaucac aacacacaca acccaccccc gaacccucaa      780

ccgccccauc caccucauuc cuucuaccca ugggccccuc cccacccgcc gaaggcucca      840

ccggagacuu cgcccuccca gucggccuaa ucgucggcgu caccgcccua ggccugcuca      900

ucaucggagu cgucaacugc guaaucauga cccaagucaa aaagaagccc cuaugucucc      960

aaagagaagc aaaaguaccu caccuccccg ccgacaaagc ccgcggcaca caaggccccg     1020

aacaacaaca ccuccuaauc accgccccau cauccuccuc aucaagccuc gaaucaucag     1080

caucagcucu cgaccgccgc gccccaacca gaaaccaacc ccaggcccca ggcguagaag     1140

ccuccggagc cggagaagcc cgagccucaa caggcuccuc cgacagcucu cccggcggcc     1200

acggcacaca aguaaacgua accugcaucg ucaauguaug cucgucaucc gaccauuccu     1260

cccaaugcuc aagccaagcc ucaucaacca ugggcgacac cgacucaagc ccaucugaau     1320

cccccaaaga cgaacaagua cccuucagua aagaagaaug ugccuuccga ucccaauuag     1380

aaacccccga aacacuccua ggauccaccg aagaaaaacc cuuaccccuc ggugucccag     1440

acgccggcau gaaacccucc uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  4726
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt9)

<400>  4726
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggucaugc gcuuguuccc gugcuuucua cagcucuugg      120

cagggcucgc acucccagcc gugcccccgc aacagugggc guuaucggcc gggaacggga      180

gcucggaagu ggaaguggua ccguuccagg aagugugggg gcgcucguac ugucgcgcgc      240

uagagcgccu ggucgauguc gugagugagu acccgagcga ggucgagcac auguucucgc      300

ccucaugcgu gagcuugcuc aggugcacgg gcuguugcgg ggacgagaac cugcacugug      360

ucccggucga gaccgcgaac gugaccaugc aauugcucaa gaucaggagc ggggacaggc      420

ccucguacgu ggaauugacc uucagccagc acguacgcug ugaaugucgc ccacucaggg      480

aaaagaugaa gccagaacgc aggcgaccga aagggcgcgg gaaaaggcgc agagaaaagc      540

aaaggcccac agacugucac uuaugcgggg acgcgguccc gaggcgcuga ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  4727
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt9)

<400>  4727
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagaccgcc agacagacac cgcgccaucg cccucguacc      120

accuccugcc cgggagaagg cgcacggucg acgccgcagc cucgcgagga caagggcccg      180

agccagcgcc aggaggcggg guagagggcg ugggagcgcg aggggucgcg cucaaacucu      240

ucguccagcu ucugggcugc agcagguucg ggggcgcagu agugcgcgca ggcgaagccg      300

agcccucagg cgcggccagg agcgcaagcu caggcagaga ggaaccccag cccgaggagg      360

gggaagaaga agaggaaaaa gaagaagaaa gggguccaca auggcgccug ggcgcgcgca      420

agccaggaag uuggaccgga gaagcagcag ugugcgcgga cucugcacca gccgcgcgag      480

cgccccaggc auuggccaga gcaucaggca gaggaggacg aguggcaaga agaggagccg      540

aggaaucagg accgccccau agcccaagca ggcgagggag ugcgagcaga gccggaccag      600

ggcgcgcaag cgagacaaug aacuuccucc ugagcugggu acacuggucg cuagcacugu      660

ugcucuaccu ccaucacgca aaauggagcc aggccgcgcc aauggccgag ggaggaggac      720

aaaaccacca cgagguagug aaauucaugg acgucuacca aaggagcuau ugccacccca      780

uagaaacgcu aguggacaua uuccaggaau auccagacga aauagaguac auauucaaac      840

caagcugcgu gccgcucaug aggugcggcg gaugcuguaa cgaugaaggg cuagagugcg      900

uacccacgga agagagcaac aucaccaugc agaucaugag gauaaaaccg caccagggcc      960

agcacauagg agagauguca uuccugcaac acaacaagug cgagugccgg cccaagaaag     1020

accgagcaag acaggaaaag aaaucaguaa ggggaaaggg caagggacag aaaagaaaaa     1080

gaaagaagag uagguacaag agcuggagug uauacguagg ggcgagaugc ugccugaugc     1140

cauggagccu accgggaccg cacccaugcg gacccugcag cgaacgcagg aaacaccugu     1200

ucguccagga cccacaaaca ugcaaguguu caugcaagaa cacagacucg cgcuguaaag     1260

cacgccaacu cgagcuuaac gaaaggacau gccgcugcga caaacccagg agauaaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4728
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt9)

<400>  4728
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuac ucagcugggu ccacugguca cucgcccucc      120

uccucuaccu ccaccacgcc aaaugguccc aagccgcccc cauggccgaa ggcggcggcc      180

aaaaccacca cgaaguagua aaauucaugg acguauacca acgcagcuac ugccacccca      240

ucgaaacccu aguagacauc uuccaagaau accccgacga aaucgaauac auauucaaac      300

ccuccugcgu cccacucaug cgcugcggcg gcugcugcaa cgacgaaggc cucgaaugcg      360

uccccacaga agaaagcaac aucacaaugc agauaaugcg aaucaaaccc caccaaggcc      420

agcacaucgg cgaaauguca uuccuccaac acaacaaaug cgaaugccga ccaaaaaaag      480

accgcgcaag acaagaaaaa aaauccguca gaggcaaagg caaaggccaa aaacgaaaac      540

gcaaaaaauc ccgcuacaaa agcuggucag ucuacguagg cgcccgcugc ugccucaugc      600

cauggucccu ccccggcccc caccccugcg ggcccugcag cgaacgccgc aaacaccucu      660

ucguccaaga cccacaaacc ugcaaaugcu ccugcaaaaa caccgacucc cgcugcaaag      720

cccgccaacu cgaacuaaac gaacgcaccu gccgcugcga caaaccccga agauaaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  4729
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt9)

<400>  4729
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccccccucc uccgccgacu ccuacuagcc gcccuccuac      120

aacucgcccc cgcacaagcc cccgucuccc aacccgacgc ccccggccac caacgcaaag      180

ucguauccug gauagacgua uacacccgcg ccaccugcca accacgagaa gucguagucc      240

cacucacagu cgaacucaug ggcaccgucg caaaacaacu cguaccauca ugcguaaccg      300

uccaacgaug cggcggcugc ugccccgacg acggccuaga augcgucccc accggccaac      360

accaagucag aaugcaaauc cucaugaucc gcuaccccuc cucccaacuc ggcgaaaugu      420

cacucgaaga acacucccaa ugcgaaugcc gccccaaaaa aaaagacuca gccguaaaac      480

ccgaccgcgc cgccacacca caccaccgac cccaaccccg cucaguccca ggcugggacu      540

ccgcccccgg cgcacccucc cccgccgaca ucacccaccc cacccccgca cccggccccu      600

ccgcacacgc cgccccaucc accaccuccg cccucacccc cggccccgcc gccgccgccg      660

ccgacgccgc cgccagcucc gucgcaaaag gcggcgccua aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  4730
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt9)

<400>  4730
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuccucg gauucuucuc cgucgccugc ucccuacucg      120

ccgccgcacu ccuccccggc ccacgcgaag caccagcagc cgccgccgca uucgaaucag      180

gccucgaccu auccgacgcc gaaccagacg ccggcgaagc caccgccuau gcaagcaaag      240

accucgaaga acaacuacga uccguaucau ccguggacga acuaaugacc guccucuacc      300

cagaauacug gaaaauguac aaaugccaac uccgaaaagg cggauggcaa cauaaccgcg      360

aacaagccaa ccucaacagc cgaaccgaag aaacaaucaa auucgccgcc gcccacuaca      420

acacggaaau acuaaaaucc aucgacaacg aauggagaaa aacacaaugc augccccgug      480

aagucugcau cgacgucggc aaagaauuug gcgucgccac caacacauuc uucaaaccac      540

ccugcgucuc aguauaccga ugcggcgggu gcugcaacuc cgaaggccua caaugcauga      600

acaccuccac cucauaccuc ucaaaaaccc ucuucgaaau aacaguucca cucagccaag      660

gccccaaacc cgucacgaua uccuucgcaa accauacuuc augccgcugc augucaaaac      720

uugacguaua ccgccaaguc cacuccauca uccgaagauc acuacccgcc acccuacccc      780

aaugucaagc cgccaacaaa accugcccca ccaacuacau guggaacaac cacauuugcc      840

gcugccuagc ccaagaagac uucauguucu caucggacgc cggcgacgac ucaaccgacg      900

gcuuccacga cauaugcggc cccaacaaag aacuagacga agaaacaugc caaugcgucu      960

gccgcgccgg ccuccgaccc gcauccugcg gaccccacaa agaacuggac cgcaacucau     1020

gccaaugcgu cugcaaaaac aaacucuucc ccucccaaug cggcgcaaac cgcgaguucg     1080

acgaaaauac cugccaaugc gucugcaagc gaaccugccc acgcaaccaa ccccucaacc     1140

ccggaaagug cgccugcgaa ugcaccgaaa gcccacaaaa augccuucuc aaaggaaaga     1200

aauuccacca ccaaaccugc ucaugcuacc gccgccccug caccaaccgc caaaaagccu     1260

gcgaacccgg cuucucauac uccgaagaag uaugccgcug cguuccaagc uacuggaaac     1320

gcccccaaau guccuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  4731
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt9)

<400>  4731
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uaccgagaau ggguagucgu caacgucuuc augaugcucu      120

acguccaacu gguccaaggu ucauccaacg aacauggccc cgucaaacgc uccucccaga      180

gcacccucga gcgcuccgaa caacaaaucc gcgcugccuc cucucuagaa gaacuucucc      240

gaaucaccca cucugaagac uggaaauuau ggcgaugccg ccuacgucuc aagagcuuca      300

ccucaaugga cucccgaucc gcaucccacc gcucuacacg auucgccgcc accuucuacg      360

acaucgaaac ccucaaaguc auagacgaag aauggcaacg cacccaaugc uccccaaggg      420

aaaccugcgu cgaaguagcc uccgaacucg gcaaauccac caacacauuc uucaaaccuc      480

ccugcgucaa cgucuuccgc ugcggcggcu gcugcaacga agaaucccuc aucugcauga      540

acacauccac cuccuacaua uccaaacaac uauucgaaau uucugucccc cucaccucgg      600

uccccgaacu cguccccguc aaaguagcca accacaccgg cugcaaaugc cugcccaccg      660

ccccacgaca ccccuauucc aucauccgac gcuccauaca gauucccgaa gaagaccgau      720

gcucccacuc aaagaaacuc ugccccauag acaugcuaug ggacucaaac aaaugcaaau      780

gcguccucca agaagaaaac ccacucgccg gcacugaaga ccacucgcac cuccaagaac      840

ccgcccucug cggaccccac augauguucg acgaagaccg cugcgaaugc gucugcaaaa      900

ccccaugccc caaagaccuc auccaacacc ccaaaaacug cucaugcuuc gaaugcaaag      960

aaucccucga gaccugcugc caaaaacaca aacucuucca ccccgauacc ugcuccugcg     1020

aagaccgcug ccccuuccac acacgcccau gcgccuccgg caaaaccgca ugcgcaaaac     1080

acugccguuu cccaaaagaa aaacgcgccg cccaaggccc ccacucccgc aaaaaccccu     1140

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  4732
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt11)

<400>  4732
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg aaaccggcuu cgaacacuca ggccucuggg      120

ucuccguacu agccggccuc cuccucggcg ccugccaagc ccaccccauc cccgacuccu      180

caccccuccu acaauucggc ggccaagucc gccaacgcua ccuauacacc gacgacgccc      240

aacaaaccga agcccaccuc gaaauccgcg aagacggcac cgucggcggc gccgccgacc      300

aaucccccga aucccuacua caacucaaag cccucaaacc uggagucauc caaauacucg      360

gcgucaaaac cucccgcuuc cucugccaac gccccgacgg agcccucuac ggcucccucc      420

acuucgaccc agaagccugc ucuuuccgag aacuccucuu agaagacggc uacaacgucu      480

accaaucuga agcccacggc cucccccuuc accuccccgg aaacaaauca ccccaccgcg      540

accccgcacc ccgcggccca gccagauucc ucccccuccc cggccuccca ccagcccucc      600

ccgaaccacc cggcauccuc gcaccccaac cacccgacgu cggcuccucc gacccccucu      660

caauggucgg ccccucccaa ggccgcuccc ccucauacgc cucauaagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  4733
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt11)

<400>  4733
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuucc caccccuccu ccuccuccug uucuggggcg      120

ucgucucaca cuccuuuccc gcuacccucg aaacccaaga acaagacguc gaccucguac      180

aaaaguaccu cgaaaaauac uacaaccuua aaaacgacgg ccgucaaguc gaaaagcgcc      240

gcaacucagg ccccgucguu gaaaaacuca aacaaaugca agaauuuuuc ggccugaaag      300

ucacaggaaa acccgacgcc gaaacccuca aagucaugaa acaaccccgc ugcggagucc      360

ccgacguagc ccaauucguc cuaaccgaag gcaacccccg cugggaacaa acccaccuca      420

cauaccgcau cgaaaacuac acccccgacc uuccccgcgc cgacgucgac cacgccauag      480

aaaaagcauu ccaauuaugg uccaacguca ccccacucac cuucacuaag gucuccgaag      540

gccaagcaga cauaaugauc ucuuucgucc gcggcgacca ccgagacaac ucccccuucg      600

acggccccgg aggcaaccug gcccacgcau uccaaccagg ccccggcauc ggaggagacg      660

cccacuucga cgaagacgaa cgcuggacaa acaauuucag agaauacaac uuacaucgcg      720

ucgccgccca cgaacucggc cacagccucg gccucucaca cuccacagau aucggcgccc      780

uaauguaccc cuccuacacc uucuccggcg acguccaacu agcccaagac gacauagacg      840

gcauccaagc cauauacggc cgaucccaaa accccguaca gcccaucgga ccacaaacuc      900

ccaaagccug cgacuccaaa cucaccuucg acgccaucac cacaauacga ggcgaaguga      960

uguucuucaa agacagauuc uauaugagaa ccaacccguu cuaccccgaa gucgaacuua     1020

acuucaucuc agucuucugg ccacaacuac caaacggccu cgaagcagcc uacgaauuug     1080

ccgaccgcga cgaaguccga uucuucaagg gcaacaaaua cugggccguc caaggccaaa     1140

acguccugca cggcuaccca aaagacaucu auuccagcuu cggcuuccca cgcacuguca     1200

aacauaucga ugccgcccuc agcgaagaaa acacaggcaa aacauacuuc uucgucgcua     1260

acaaauacug gcgcuacgau gaauacaaac gcuccaugga cccaggcuau ccuaaaauga     1320

ucgcccacga cuuccccggc aucggccaca aggucgaugc cgucuucaug aaggacggau     1380

ucuucuacuu cuuccacgga acccgccaau acaaguucga ccccaaaacu aagcgaaucc     1440

ucacccucca aaaagccaac uccugguuca acugccgcaa aaacuaagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  4734
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt11)

<400>  4734
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauucauucc caccacuacu acuccuccua uucuggggag      120

ucgucuccca uuccuucguc cucacagaag gcaacccccg cugggaacaa acccaccuca      180

ccuaccgcau agaaaacuac accccagacc ucccccgcgc cgacgucgac cacgccaucg      240

aaaaagcguu ccaacuaugg ucuaacguaa caccccucac cuucaccaaa gucuccgaag      300

gccaagccga cauaaugauc ucauucguca gaggcgacca ccgcgacaac ucucccuucg      360

acggccccgg aggcaaccuc gcacacgccu uccaacccgg ccccggaauc ggcggcgacg      420

cccacuucga cgaagacgaa cgcuggacca acaacuuccg agaauacaac cuccaccgcg      480

ucgccgcaca cgaacucggc cacagccucg ggcucucaca cuccaccgac aucggugccc      540

ucauguaccc cucauacaca uucucuggcg acguccaacu cgcacaagac gacaucgacg      600

gcauccaagc caucuacggc cgaucccaaa acccagucca acccauaggc ccacagacac      660

ccaaagcaug cgacuccaaa cucaccuucg acgccauaac caccauccgc ggcgaaguaa      720

uguucuucaa agacagauuc uacaugcgca ccaaccccuu cuacccagaa guugaauuaa      780

acuucaucuc cgucuucugg ccacagcucc caaacggucu cgaagccgca uacgaauuug      840

cagaccgaga cgaaguacga uucuucaaag gcaacaaaua uugggccgua caggggcaaa      900

auguccucca cggcuacccu aaagacaucu acuccuccuu cggcuucccc cgcacaguca      960

aacacaucga cgccgcccuc uccgaagaaa acaccggcaa aaccuacuuc uucgucgcca     1020

acaaauacug gcgauacgac gaauacaaac gcuccaugga ccccggauac cccaaaauga     1080

ucgcccacga cuuccccggc aucggccaca aaguagacgc cguuuucaug aaagacggau     1140

ucuucuacuu cuuccacgga acaagacagu acaaauucga cccaaagacc aaacggaucc     1200

ucacccucca aaaagcaaac uccugguuca auugccgcaa aaauuaagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  4735
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt11)

<400>  4735
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaagaaca uccugaagau ccucauggac agcuacucca      120

aggagagcaa gauccagacc gugcgccggg ucaccuccgu gagccugcug gccguguacc      180

ucacgaugaa caccuccagc cugguccugg ccaagcccau cgagaacacc aacgacaccu      240

ccaucaagaa cguggagaag cuccgcaacg cgccgaacga ggagaacagc aagaaggugg      300

aggacuccaa gaacgacaag gucgagcacg ugaagaacau cgaggaggcc aagguggagc      360

aggucgcccc cgaggucaag agcaagucca cgcugcggag cgccuccauc gccaacacca      420

acagcgagaa guacgacuuc gaguaccuga acggccucuc cuacaccgag cugaccaacc      480

ugaucaagaa caucaagugg aaccagauca acggccucuu caacuacagc acgggguccc      540

agaaguucuu cggggacaag aaccgcgugc aggcgaucau caacgcccug caggagagcg      600

gccggaccua caccgccaac gacaugaagg ggaucgagac cuucacggag gugcugcgcg      660

ccggcuucua ccucggcuac uacaacgacg ggcuguccua ccugaacgac cggaacuucc      720

aggacaagug cauccccgcg augaucgcca uccagaagaa ccccaacuuc aagcucggca      780

ccgccgugca ggacgaggug aucaccagcc uggggaagcu gaucggcaac gccagcgcca      840

acgcggaggu cgugaacaac ugcgugccgg uccucaagca guuccgcgag aaccugaacc      900

aguacgcccc cgacuacgug aaggggaccg ccgugaacga gcugaucaag ggcaucgagu      960

ucgacuucuc cggcgccgcc uacgagaagg acgucaagac gaugcccugg uacgggaaga     1020

ucgaccccuu caucaacgag cucaaggcgc ugggccugua cgggaacauc accagcgcca     1080

ccgagugggc cuccgacgug ggcaucuacu accucagcaa guucggccug uacuccacca     1140

accggaacga caucgugcag agccuggaga aggccgucga cauguacaag uacgggaaga     1200

ucgccuucgu ggcgauggag cgcaucacgu gggacuacga cggcaucggg uccaacggca     1260

agaaggucga ccacgacaag uuccucgacg acgccgagaa gcacuaccug ccgaagaccu     1320

acaccuucga caacgggacc uucaucaucc gggccggcga caaggugagc gaggagaaga     1380

ucaagcgccu guacugggcc ucccgggagg ucaagagcca guuccaccgc guggugggca     1440

acgacaaggc ccucgaggug gggaacgcgg acgacguccu gacgaugaag aucuucaacu     1500

cccccgagga guacaaguuc aacaccaaca ucaacggcgu gagcaccgac aacgggggcc     1560

uguacaucga gccccggggg accuucuaca cguacgagcg cacgccccag caguccaucu     1620

ucagccucga ggagcuguuc cggcacgagu acacccacua ccugcaggcc cgcuaccucg     1680

uggacggccu guggggccag gggccguucu acgagaagaa ccggcugacc ugguucgacg     1740

agggcaccgc cgaguucuuc gccgggucca cccgcaccag cggcguccuc ccccggaagu     1800

ccauccuggg guaccuggcg aaggacaagg uggaccaccg cuacagccuc aagaagaccc     1860

ugaacuccgg cuacgacgac agcgacugga uguucuacaa cuacggcuuc gccguggccc     1920

acuaccugua cgagaaggac augcccacgu ucaucaagau gaacaaggcc auccucaaca     1980

ccgacgucaa gagcuacgac gagaucauca agaagcuguc cgacgacgcc aacaagaaca     2040

ccgaguacca gaaccacauc caggagcugg cggacaagua ccagggggcc ggcauccccc     2100

uggugagcga cgacuaccuc aaggaccacg gguacaagaa ggccuccgag guguacagcg     2160

agaucuccaa ggccgccagc cugaccaaca ccuccgucac ggcggagaag ucccaguacu     2220

ucaacaccuu cacccugcgc ggcaccuaca cgggcgagac cagcaagggg gaguucaagg     2280

acugggacga gaugagcaag aagcucgacg gcacccugga gucccuggcc aagaacagcu     2340

gguccgggua caagacccuc acggccuacu ucaccaacua ccgggugacc agcgacaaca     2400

aggugcagua cgacgucgug uuccacggcg ugcugaccga caacgccgac aucuccaaca     2460

acaaggcccc gaucgcgaag gucacggggc ccagcaccgg cgccgugggc cgcaacaucg     2520

aguucuccgg gaaggacagc aaggacgagg acggcaagau cgugagcuac gacugggacu     2580

ucggggacgg cgccaccucc cgggggaaga acagcgucca cgccuacaag aaggcgggca     2640

ccuacaacgu gacgcugaag gugaccgacg acaagggcgc caccgccacc gaguccuuca     2700

cgaucgagau caagaacgag gacaccacca cccccaucac gaaggagaug gagcccaacg     2760

acgacaucaa ggaggccaac gggccgaucg ucgagggcgu gaccgugaag ggggaccuca     2820

acggcagcga cgacgccgac accuucuacu ucgacgucaa ggaggacggg gacgugacca     2880

ucgagcugcc cuacuccggc agcuccaacu ucacguggcu gguguacaag gagggcgacg     2940

accagaacca caucgcgagc gggaucgaca agaacaacuc caaggucggc accuucaaga     3000

gcaccaaggg gcgccacuac guguucaucu acaagcacga cuccgccagc aacaucuccu     3060

acagccucaa caucaagggc cuggggaacg agaagcugaa ggagaaggag aacaacgacu     3120

ccagcgacaa ggccaccgug auccccaacu ucaacacgac caugcagggc ucccuccugg     3180

gcgacgacag ccgggacuac uacuccuucg aggucaagga ggagggggag gugaacaucg     3240

agcuggacaa gaaggacgag uucggcguga ccuggacccu ccaccccgag agcaacauca     3300

acgaccgcau cacguacggg caggucgacg gcaacaaggu gagcaacaag gugaagcugc     3360

ggccgggcaa guacuaccug cucgucuaca aguacuccgg gagcggcaac uacgagcugc     3420

gcgugaacaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  4736
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt11)

<400>  4736
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga cauucaucag ccuccucuuc uuauucucca      120

gcgccuacuc caucgccaac accaacagcg agaaguacga cuucgaguac cugaacggcc      180

ucucuuacac ggagcugacc aaucugauca agaacaucaa guggaaccag auuaacgggu      240

uauucaacua cagcaccggc ucccagaagu ucuucgggga caaaaaccgc guccaggcga      300

uuaucaacgc ccugcaggag agcggucgga ccuacaccgc uaacgacaug aaggggaucg      360

agaccuucac cgagguucug cgcgccggcu ucuaccucgg cuacuacaac gacgggcugu      420

ccuaccugaa cgaccggaac uuccaggaca agugcauccc cgccaugauc gcgauccaga      480

agaacccgaa cuucaagcuc ggcaccgccg ugcaggacga ggucaucacg agccugggga      540

agcugaucgg caacgccucc gccaacgcgg agguggugaa caacugcguc cccgugcuca      600

agcaauuccg cgaaaaccug aaccaguacg cccccgacua cguaaagggg accgccguca      660

acgagcugau caagggcauc gaguucgacu uuagcggcgc cgccuacgag aaagacguga      720

agaccaugcc cugguacggg aagaucgacc cguucaucaa cgagcucaag gcgcugggcc      780

uguacgggaa caucaccucc gccacggagu gggccagcga cgugggcauc uacuaccucu      840

ccaaguucgg ccuguacucg accaaccgga augacaucgu acagucccug gagaaggccg      900

uggacaugua caaguacggg aagaucgccu ucguggcgau ggagcgcauc accugggacu      960

acgacgguau cgggagcaac ggcaagaagg ucgaccacga caaauuccuc gacgacgccg     1020

agaagcacua ccugcccaag accuacacgu ucgacaacgg caccuucauc auccgggccg     1080

gugacaaggu guccgaggag aagaucaagc gccuguacug ggccagccga gaggucaaga     1140

gccaguucca ccgcguggug ggcaacgaca aggcccucga gguggggaac gcggacgacg     1200

uccugaccau gaagaucuuc aacuccccug aggaguacaa guucaacacc aacaucaacg     1260

gcguguccac ggauaacggg ggccuguaca ucgagccccg ggggaccuuc uacaccuaug     1320

agcgcacccc gcagcagucc aucuucagcc ucgaggagcu guuucggcac gaguacacgc     1380

acuaccugca ggcccgcuac uuaguggacg gccugugggg ccaggggccc uucuacgaga     1440

agaaccggcu gaccugguuc gacgagggca ccgccgaguu cuucgccggu uccacccgca     1500

cgagcggcgu ccucccccga aaguccaucc ugggguaccu ggccaaggac aagguggacc     1560

accgcuacag ccucaagaag acccugaacu ccggcuacga cgacucggac uggauguucu     1620

acaacuacgg cuucgcgguc gcccacuacc uguacgagaa ggacaugccc accuucauca     1680

agaugaacaa ggccauccuc aacaccgacg ugaaguccua cgacgagauc aucaagaagc     1740

ugagcgacga cgccaacaag aacacggagu accagaacca cauccaggag cuggcggaca     1800

aauaccaggg ugccggcauc ccucucgugu ccgacgacua ccugaaggac cacggguaca     1860

agaaggccag cgaggucuac uccgagauua gcaaggccgc cucccugacc aacaccagcg     1920

ugaccgcgga gaagucccag uacuucaaca cguucacccu ccggggcacc uacaccggcg     1980

aaaccagcaa gggggaguuc aaggacuggg acgagaugag caagaagcug gacggcacgc     2040

uggaaucccu ggccaagaac agcugguccg gguacaagac ccucaccgcc uauuuuacca     2100

acuaccgcgu gacgagcgac aacaaggucc aguacgacgu gguguuccac ggcguccuga     2160

ccgacaacgc cgacaucucc aacaacaagg cccccaucgc gaaggugacc gggcccagca     2220

ccggcgccgu gggccggaac aucgaguucu ccgggaagga cucuaaggac gaggacggca     2280

agauagucuc cuacgacugg gacuucgggg acggcgccac gucccgcggg aagaacuccg     2340

uccacgccua caagaaggcc ggcaccuaca acgugacccu gaaggucacc gacgacaaag     2400

gcgcgacggc caccgagagc uucaccaucg agaucaagaa cgaggacacc acgaccccca     2460

ucaccaagga gauggagccg aacgacgaca ucaaggaggc caacgggccc aucguggagg     2520

gcgugaccgu caagggggac cucaacggcu ccgacgacgc agacacguuc uacuucgaug     2580

ugaaggagga cggggacgug accaucgagc ugcccuacag cggcuccagc aacuucaccu     2640

ggcuggucua caaggagggc gacgaccaga accacaucgc guccgggauc gacaagaaca     2700

acagcaaggu gggcaccuuc aagagcacga aggggcgcca cuacguguuc aucuacaagc     2760

acgacuccgc cagcaacauc uccuacagcc ucaacaucaa gggccugggg aacgagaagc     2820

ugaaggagaa ggagaacaac gacuccagcg acaaggccac cgucaucccc aacuucaaca     2880

ccaccaugca gggcucccuc cugggcgacg acagccggga cuacuacucc uucgagguga     2940

aggaggaggg ggaggugaac aucgagcugg acaagaagga cgaguucggc gucacgugga     3000

cccuccaccc ggaauccaac auaaacgacc gcaucaccua cggccaggug gacgggaaca     3060

agguguccaa caaggucaag cugcggcccg gcaaguacua ccugcucgug uacaaguaca     3120

gcggguccgg aaacuacgag cugcgcguga acaagugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  4737
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt11)

<400>  4737
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccuccucuuc cuguucucca      120

gcgccuacuc caugaagaag aacauccuga agauccucau ggacagcuac uccaaggaga      180

gcaagaucca gaccguccgc cgggugacgu ccgugagccu gcuggccguc uaccucacca      240

ugaacaccuc cagccuggug cuggcgaagc ccaucgagaa caccaacgac acguccauca      300

agaacgugga gaagcuccgc aacgccccga acgaggagaa cagcaagaag gucgaggacu      360

ccaagaacga caagguggag cacgugaaga acaucgagga ggccaagguc gagcaggucg      420

cccccgaggu caagagcaag uccacccugc ggagcgccuc ccgccggcgc cggaagcgca      480

ucgcgaacac caacagcgag aaguacgacu ucgaguaccu gaacggccuc uccuacaccg      540

agcugacgaa ccugaucaag aacaucaagu ggaaccagau caacgggcug uucaacuaca      600

gcaccggcag ccagaaguuc uucggggaca agaaccgggu gcaggccauc aucaacgccc      660

ugcaggaguc cggccgcacc uacaccgcca acgacaugaa ggggaucgag acguucaccg      720

aggugcugcg ggcgggcuuc uaccucggcu acuacaacga cgggcugagc uaccugaacg      780

accgcaacuu ccaggacaag ugcauccccg ccaugaucgc cauccagaag aaccccaacu      840

ucaagcucgg caccgccgug caggacgagg ugaucaccuc ccuggggaag cugaucggca      900

acgccagcgc gaacgccgag guggugaaca acugcguccc ggugcucaag caguuccggg      960

agaaccugaa ccaguacgcc cccgacuacg ugaaggggac ggccgucaac gagcugauca     1020

agggcaucga guucgacuuc uccggcgccg cguacgagaa ggacgugaag accaugcccu     1080

gguacgggaa gaucgacccc uucaucaacg agcucaaggc ccugggccug uacgggaaca     1140

ucaccagcgc caccgagugg gccuccgacg ugggcaucua cuaccucagc aaguucggcc     1200

uguacuccac gaaccgcaac gacaucgucc agagccugga gaaggccgug gacauguaca     1260

aguacgggaa gaucgcguuc gucgccaugg agcggaucac cugggacuac gacggcaucg     1320

gguccaacgg caagaaggug gaccacgaca aguuccucga cgacgccgag aagcacuacc     1380

ugccgaagac cuacaccuuc gacaacggga cguucaucau ccgcgccggc gacaagguga     1440

gcgaggagaa gaucaagcgg cuguacuggg ccucccgcga ggucaagagc caguuccacc     1500

gggugguggg caacgacaag gcgcucgagg ucgggaacgc cgacgacgug cugaccauga     1560

agaucuucaa cucccccgag gaguacaagu ucaacaccaa caucaacggc gugagcaccg     1620

acaacggggg ccuguacauc gagccccgcg ggacguucua caccuacgag cggacgcccc     1680

agcaguccau cuucagccuc gaggagcugu uccgccacga guacacccac uaccugcagg     1740

cccgcuaccu cgucgacggc cuguggggcc aggggccguu cuacgagaag aaccggcuga     1800

ccugguucga cgagggcacc gccgaguucu ucgcgggguc cacccgcacc agcggcgugc     1860

ucccccgcaa gagcauccug ggguaccugg ccaaggacaa gguggaccac cgguacuccc     1920

ucaagaagac gcugaacagc ggcuacgacg acuccgacug gauguucuac aacuacggcu     1980

ucgccgucgc ccacuaccug uacgagaagg acaugcccac cuucaucaag augaacaagg     2040

ccauccugaa caccgacguc aagagcuacg acgagaucau caagaagcuc uccgacgacg     2100

cgaacaagaa caccgaguac cagaaccaca uccaggagcu ggccgacaag uaccaggggg     2160

ccggcauccc ccuggugagc gacgacuacc ucaaggacca cggguacaag aaggccuccg     2220

agguguacag cgagaucucc aaggccgcga gccugaccaa cacguccgug accgccgaga     2280

agucccagua cuucaacacc uucacccugc ggggcacgua caccggcgag accagcaagg     2340

gggaguucaa ggacugggac gagaugagca agaagcucga cggcacccug gagucccugg     2400

ccaagaacag cugguccggg uacaagacgc ucaccgccua cuucaccaac uaccgcguga     2460

ccagcgacaa caagguccag uacgacgugg uguuccacgg cguccugacg gacaacgccg     2520

acaucagcaa caacaaggcg ccgaucgcca aggugaccgg gcccuccacc ggcgccgugg     2580

gccggaacau cgaguucagc gggaaggacu ccaaggacga ggacggcaag aucgucagcu     2640

acgacuggga cuucggggac ggcgccaccu cccgcgggaa gaacagcgug cacgcguaca     2700

agaaggccgg cacguacaac gugacccuga aggucaccga cgacaagggc gccaccgcca     2760

cggaguccuu caccaucgag aucaagaacg aggacaccac cacgcccauc accaaggaga     2820

uggagcccaa cgacgacauc aaggaggcca acgggccgau cguggagggc gugaccguca     2880

agggggaccu caacggcagc gacgacgcgg acaccuucua cuucgacgug aaggaggacg     2940

gggacgugac gaucgagcug cccuacuccg gcagcuccaa cuucaccugg cuggucuaca     3000

aggagggcga cgaccagaac cacaucgcca gcgggaucga caagaacaac uccaaggugg     3060

gcaccuucaa gagcaccaag gggcggcacu acguguucau cuacaagcac gacuccgcca     3120

gcaacaucuc cuacagccuc aacaucaagg gccuggggaa cgagaagcug aaggagaagg     3180

agaacaacga cuccagcgac aaggccacgg ucauccccaa cuucaacacc accaugcagg     3240

gcagccuccu gggcgacgac ucccgcgacu acuacagcuu cgaggugaag gaggaggggg     3300

aggugaacau cgagcuggac aagaaggacg aguucggcgu caccuggacg cuccaccccg     3360

aguccaacau caacgaccgg aucaccuacg gccaggugga cgggaacaag gugagcaaca     3420

aggucaagcu gcgcccgggc aaguacuacc ugcucgugua caaguacucc gggagcggca     3480

acuacgagcu gcgggugaac aagugaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  4738
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt11)

<400>  4738
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuga agaucauccu caaccgcggc aagaccauga      120

agcggaagug ccugagcaag cgccugaugc ucgccaucac cauggccacg aucuucaccg      180

ugaacuccac ccugcccauc uacgcggccg ucgacaagaa caacgccacc gccgccgugc      240

agaacgagag caagcgguac acgguguccu accugaagac ccucaacuac uacgaccugg      300

ucgaccugcu cgugaagacc gagaucgaga accugccgga ccuguuccag uacagcuccg      360

acgcgaagga guucuacggg aacaagaccc gcaugagcuu caucauggac gagaucggcc      420

ggcgcgcgcc ccaguacacg gagaucgacc acaaggggau ccccacccuc guggaggucg      480

ugcgggccgg cuucuaccug ggguuccaca acaaggagcu gaacgagauc aacaagcgcu      540

ccuucaagga gcgggugauc cccagcaucc ucgccaucca gaagaacccg aacuucaagc      600

ugggcaccga gguccaggac aagaucgugu ccgccaccgg ccugcucgcc gggaacgaga      660

cggccccgcc cgaggugguc aacaacuuca cccccauccu gcaggacugc aucaagaaca      720

ucgaccgcua cgcccuggac gaccucaaga gcaaggcccu guucaacgug cuggcggccc      780

cgaccuacga caucaccgag uaccuccggg ccacgaagga gaagcccgag aacacccccu      840

gguacggcaa gaucgacggg uucaucaacg agcugaagaa gcuggcccuc uacggcaaga      900

ucaacgacaa caacuccugg aucaucgaca acgggaucua ccacaucgcg ccccugggca      960

agcugcacag caacaacaag aucggcaucg agacccucac cgaggugaug aaggucuacc     1020

cguaccuguc caugcagcac cuccagagcg ccgaccagau caagcgccac uacgacucca     1080

aggacgccga ggggaacaag aucccccugg acaaguucaa gaaggagggc aaggagaagu     1140

acugccccaa gacguacacc uucgacgacg ggaaggugau caucaaggcc ggcgcccggg     1200

uggaggagga gaaggucaag cgccuguacu gggccagcaa ggaggugaac ucccaguucu     1260

uccgggugua cggcaucgac aagccccugg aggaggggaa cccggacgac auccucacca     1320

uggucaucua caacagcccc gaggaguaca agcugaacuc cgugcuguac ggcuacgaca     1380

ccaacaacgg gggcauguac aucgagcccg aggggacguu cuucaccuac gagcgcgagg     1440

cgcaggagag caccuacacc cucgaggagc uguuccggca cgaguacacg cacuaccugc     1500

agggccgcua cgccgugccc ggccaguggg ggcggaccaa gcucuacgac aacgaccgcc     1560

ugaccuggua cgaggagggc ggggccgagc uguucgccgg cagcacccgg acguccggga     1620

uccucccgcg caagagcauc gucuccaaca uccacaacac cacccgcaac aaccgguaca     1680

agcugagcga caccgugcac uccaaguacg gcgccagcuu cgaguucuac aacuacgcgu     1740

gcauguucau ggacuacaug uacaacaagg acaugggcau ccugaacaag cucaacgacc     1800

uggccaagaa caacgacguc gacggguacg acaacuacau ccgcgaccug uccagcaacu     1860

acgcccugaa cgacaaguac caggaccaca ugcaggagcg gaucgacaac uacgagaacc     1920

ucacggugcc cuucguggcc gacgacuacc ugguccgcca cgcguacaag aaccccaacg     1980

agaucuacuc cgagaucagc gagguggcca agcugaagga cgccaagucc gaggugaaga     2040

agucccagua cuucagcacc uucacccucc ggggcagcua caccgggggc gccuccaagg     2100

ggaagcugga ggaccagaag gccaugaaca aguucaucga cgacagccug aagaagcucg     2160

acaccuacuc cuggagcggc uacaagacgc ugaccgcgua cuucaccaac uacaaggucg     2220

acuccagcaa ccgcgugacc uacgacgugg ucuuccacgg cuaccugccc aacgaggggg     2280

acagcaagaa cucccucccg uacggcaaga ucaacgggac guacaagggc accgagaagg     2340

agaagaucaa guucagcucc gagggcagcu ucgaccccga cgggaagauc guguccuacg     2400

agugggacuu cggcgacggg aacaagagca acgaggagaa ccccgagcac uccuacgaca     2460

aggugggcac cuacaccguc aagcugaagg ugacggacga caagggggag agcuccguga     2520

gcaccaccac cgccgagauc aaggaccugu ccgagaacaa gcuccccguc aucuacaugc     2580

acgugcccaa gagcggcgcc cugaaccaga agguggucuu cuacggcaag gggacguacg     2640

accccgacgg cuccaucgcc ggguaccagu gggacuucgg cgacgggagc gacuucucca     2700

gcgagcagaa ccccucccac guguacacca agaagggcga guacaccgug acccugcggg     2760

ucauggacag cagcggccag auguccgaga agacgaugaa gaucaagauc accgacccgg     2820

uguaccccau cgggaccgag aaggagccca acaacagcaa ggagaccgcc uccggcccca     2880

ucgugccggg gauccccguc agcggcacga ucgagaacac cuccgaccag gacuacuucu     2940

acuucgacgu gaucaccccc ggggagguga agaucgacau caacaagcuc ggcuacggcg     3000

gggcgaccug ggucguguac gacgagaaca acaacgccgu gagcuacgcc acggacgacg     3060

gccagaaccu guccgggaag uucaaggccg acaagcccgg ccgcuacuac auccaccugu     3120

acauguucaa cgggagcuac augccguacc ggaucaacau cgagggcucc gucggccgcu     3180

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  4739
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt11)

<400>  4739
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcgcaagu gccugagcaa gcggcucaug cuggccauca      120

ccauggccac caucuucacg gugaacucca cccugcccau cuacgcggcc gucgacaaga      180

acaacgccac cgccgccgug cagaacgaga gcaagcgcua caccgugucc uaccucaaga      240

cgcugaacua cuacgaccug gucgaccucc uggugaagac cgagaucgag aaccugccgg      300

accucuucca guacagcucc gacgcgaagg aguucuacgg caacaagacc cggaugagcu      360

ucaucaugga cgagaucggg cgccgggcgc cccaguacac cgagaucgac cacaagggca      420

uccccacgcu gguggagguc gugcgcgccg gguucuaccu gggcuuccac aacaaggagc      480

ucaacgagau caacaagcgg uccuucaagg agcgcgugau ccccagcauc cuggccaucc      540

agaagaaccc gaacuucaag cuggggaccg agguccagga caagaucgug uccgccaccg      600

gccuccuggc cggcaacgag accgccccgc ccgagguggu caacaacuuc acgcccaucc      660

ugcaggacug caucaagaac aucgaccggu acgcccucga cgaccucaag agcaaggccc      720

uguucaacgu gcucgcggcc ccgaccuacg acaucaccga guaccugcgc gccaccaagg      780

agaagcccga gaacacgccc ugguacggga agaucgacgg cuucaucaac gagcugaaga      840

agcucgcccu guacgggaag aucaacgaca acaacuccug gaucaucgac aacggcaucu      900

accacaucgc gccccugggg aagcuccaca gcaacaacaa gaucggcauc gagacccuga      960

ccgaggugau gaaggucuac ccguaccugu ccaugcagca ccuccagagc gccgaccaga     1020

ucaagcggca cuacgacucc aaggacgccg agggcaacaa gaucccccug gacaaguuca     1080

agaaggaggg gaaggagaag uacugcccca agaccuacac guucgacgac ggcaagguga     1140

ucaucaaggc cggggcccgc guggaggagg agaaggucaa gcggcuguac ugggccagca     1200

aggaggugaa cucccaguuc uuccgcgugu acggcaucga caagccccuc gaggagggca     1260

acccggacga cauccugacc auggucaucu acaacagccc cgaggaguac aagcugaacu     1320

ccgugcucua cggguacgac accaacaacg gcgggaugua caucgagccc gagggcaccu     1380

ucuucacgua cgagcgggag gcgcaggaga gcaccuacac ccuggaggag cuguuccgcc     1440

acgaguacac ccacuaccuc caggggcggu acgccgugcc cggccagugg ggccgcacga     1500

agcuguacga caacgaccgg cugaccuggu acgaggaggg cggggccgag cuguucgccg     1560

ggagcacccg caccuccggc auccugccgc gcaagagcau cgucuccaac auccacaaca     1620

cgacccggaa caaccgcuac aagcugagcg acaccgugca cuccaaguac ggggccagcu     1680

ucgaguucua caacuacgcg ugcauguuca uggacuacau guacaacaag gacaugggca     1740

uccucaacaa gcugaacgac cuggccaaga acaacgacgu cgacggcuac gacaacuaca     1800

uccgggaccu cuccagcaac uacgcccuga acgacaagua ccaggaccac augcaggagc     1860

gcaucgacaa cuacgagaac cugaccgugc ccuucguggc cgacgacuac cugguccggc     1920

acgcguacaa gaaccccaac gagaucuacu ccgagaucag cgagguggcc aagcucaagg     1980

acgccaaguc cgaggugaag aagucccagu acuucagcac guucacccug cgcgggagcu     2040

acaccggcgg ggccuccaag ggcaagcugg aggaccagaa ggccaugaac aaguucaucg     2100

acgacagccu caagaagcug gacaccuacu ccuggagcgg guacaagacc cugacggcgu     2160

acuucaccaa cuacaagguc gacuccagca accgggugac cuacgacgug gucuuccacg     2220

gcuaccuccc caacgagggc gacagcaaga acucccugcc guacgggaag aucaacggca     2280

ccuacaaggg gacggagaag gagaagauca aguucagcuc cgagggcagc uucgaccccg     2340

acggcaagau cguguccuac gagugggacu ucggggacgg caacaagagc aacgaggaga     2400

accccgagca cuccuacgac aaggugggga ccuacaccgu caagcugaag gugaccgacg     2460

acaagggcga gagcuccgug agcacgacca ccgccgagau caaggaccuc uccgagaaca     2520

agcugcccgu caucuacaug cacgugccca agagcggggc ccugaaccag aagguggucu     2580

ucuacggcaa gggcaccuac gaccccgacg gguccaucgc cggcuaccag ugggacuucg     2640

gggacggcag cgacuucucc agcgagcaga accccuccca cguguacacg aagaaggggg     2700

aguacaccgu gacccuccgc gucauggaca gcagcggcca gauguccgag aagaccauga     2760

agaucaagau cacggacccg guguacccca ucggcaccga gaaggagccc aacaacagca     2820

aggagaccgc cuccgggccc aucgugccgg gcauccccgu cagcgggacc aucgagaaca     2880

cguccgacca ggacuacuuc uacuucgacg ugaucacccc cggcgaggug aagaucgaca     2940

ucaacaagcu gggguacggc ggcgcgaccu gggucgugua cgacgagaac aacaacgccg     3000

ugagcuacgc caccgacgac gggcagaacc uguccggcaa guucaaggcc gacaagcccg     3060

ggcgguacua cauccaccuc uacauguuca acggcagcua caugccguac cgcaucaaca     3120

ucgagggguc cgucggccgg ugaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  4740
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt11)

<400>  4740
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcuguuc cuguucucca      120

gcgccuacuc cguccagaac gagagcaagc gcuacaccgu guccuaccug aagacgcuca      180

acuacuacga ccugguggac cugcucguca agaccgagau cgagaaccug cccgaccugu      240

uccaguacag cuccgacgcc aaggaguucu acggcaacaa gacccggaug agcuucauca      300

uggacgagau cgggcgccgg gcgccgcagu acaccgagau cgaccacaag ggcaucccca      360

cgcucgugga ggugguccgc gccggguucu accugggcuu ccacaacaag gagcugaacg      420

agaucaacaa gcgguccuuc aaggagcgcg ugauccccag cauccucgcc auccagaaga      480

accccaacuu caagcugggg accgaggugc aggacaagau cgucuccgcc accggccugc      540

ucgccggcaa cgagaccgcg ccgcccgagg uggugaacaa cuucacgccc auccugcagg      600

acugcaucaa gaacaucgac cgguacgccc uggacgaccu caagagcaag gcccuguuca      660

acguccuggc cgcgcccacc uacgacauca ccgaguaccu ccgcgccacc aaggagaagc      720

cggagaacac gcccugguac gggaagaucg acggcuucau caacgagcug aagaagcugg      780

cccucuacgg gaagaucaac gacaacaacu ccuggaucau cgacaacggc aucuaccaca      840

ucgcgccccu ggggaagcug cacagcaaca acaagaucgg caucgagacc cucaccgagg      900

ugaugaaggu guaccccuac cuguccaugc agcaccucca gagcgccgac cagaucaagc      960

ggcacuacga cuccaaggac gccgagggca acaagauccc gcucgacaag uucaagaagg     1020

aggggaagga gaaguacugc cccaagaccu acacguucga cgacggcaag gucaucauca     1080

aggccggggc ccgcguggag gaggagaagg ugaagcggcu guacugggcc agcaaggagg     1140

ucaacuccca guucuuccgc guguacggca ucgacaagcc ccuggaggag ggcaaccccg     1200

acgacauccu caccauggug aucuacaaca gcccggagga guacaagcug aacagcgucc     1260

uguacgggua cgacaccaac aacggcggga uguacaucga gcccgagggc accuucuuca     1320

cguacgagcg ggaggcccag gaguccaccu acacccucga ggagcuguuc cgccacgagu     1380

acacccacua ccugcagggg cgguacgcgg ugcccggcca guggggccgc acgaagcucu     1440

acgacaacga ccggcugacc ugguacgagg agggcggggc cgagcuguuc gccgggagca     1500

cccgcaccuc cggcauccuc ccccgcaaga gcaucguguc caacauccac aacacgaccc     1560

ggaacaaccg guacaagcug agcgacaccg uccacuccaa guacggggcc agcuucgagu     1620

ucuacaacua cgccugcaug uucauggacu acauguacaa caaggacaug ggcauccuga     1680

acaagcucaa cgaccuggcg aagaacaacg acguggacgg cuacgacaac uacauccgcg     1740

accuguccag caacuacgcc cucaacgaca aguaccagga ccacaugcag gagcgcaucg     1800

acaacuacga gaaccugacc gucccguucg uggccgacga cuaccuggug cggcacgccu     1860

acaagaaccc caacgagauc uacuccgaga ucagcgaggu cgccaagcug aaggacgcga     1920

aguccgaggu gaagaagucc caguacuuca gcacguucac ccuccgcggg agcuacaccg     1980

gcggggccuc caagggcaag cuggaggacc agaaggccau gaacaaguuc aucgacgaca     2040

gccugaagaa gcucgacacc uacuccugga gcggguacaa gacgcugacc gccuacuuca     2100

ccaacuacaa gguggacagc uccaaccggg ucaccuacga cgugguguuc cacggcuacc     2160

ugcccaacga gggcgacagc aagaacuccc uccccuacgg gaagaucaac ggcaccuaca     2220

aggggacgga gaaggagaag aucaaguuca gcuccgaggg cagcuucgac ccggacggca     2280

agaucgucuc cuacgagugg gacuucgggg acggcaacaa gagcaacgag gagaaccccg     2340

agcacuccua cgacaaggug gggaccuaca ccgugaagcu gaaggucacc gacgacaagg     2400

gcgagagcuc cgugagcacg accaccgcgg agaucaagga ccuguccgag aacaagcucc     2460

ccgugaucua caugcacguc cccaagagcg gggcccugaa ccagaaggug guguucuacg     2520

gcaagggcac cuacgacccg gacgggucca ucgccggcua ccagugggac uucggggacg     2580

gcagcgacuu cuccagcgag cagaacccca gccacgucua cacgaagaag ggggaguaca     2640

ccgugacccu gcgcgugaug gacuccagcg gccagauguc cgagaagacc augaagauca     2700

agaucacgga ccccgucuac ccgaucggca ccgagaagga gcccaacaac agcaaggaga     2760

ccgccuccgg gcccaucgug cccggcaucc cggugagcgg gaccaucgag aacacguccg     2820

accaggacua cuucuacuuc gacgucauca cccccggcga ggugaagauc gacaucaaca     2880

agcucgggua cggcggcgcc accugggugg ucuacgacga gaacaacaac gcggugagcu     2940

acgccaccga cgacgggcag aaccuguccg gcaaguucaa ggccgacaag cccgggcggu     3000

acuacaucca ccuguacaug uucaacggca gcuacaugcc cuaccgcauc aacaucgagg     3060

gguccguggg ccggugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4741
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt11)

<400>  4741
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccucuuauuc cuguuuucca      120

gugccuacuc caugaagcgc aagugccuga gcaagcggcu caugcuggcc aucaccaugg      180

cgacgaucuu caccgucaac uccacccugc ccaucuacgc cgccguggac aagaacaacg      240

ccaccgccgc gcgccggcgc cggaagcgcg ugcagaacga gagcaagcgg uacacggucu      300

ccuaccucaa gacccugaac uacuacgacc ugguggaccu ccuggugaag accgagaucg      360

agaaccugcc ggaccucuuc caguacagcu cagacgccaa ggaguucuac ggcaacaaga      420

cccgcaugag cuucaucaug gacgagaucg ggcggcgcgc gccccaguac acggagaucg      480

accacaaggg cauucccacc cuggucgagg uggugcgggc cggguucuac cugggcuucc      540

acaacaagga gcucaaugag aucaacaagc gcuccuucaa ggagcgaguc aucccaagca      600

uccuggccau ccagaagaac ccgaacuuca agcuggggac cgaggugcag gacaagaucg      660

uguccgccac cggccuccuc gccggcaacg agacggcccc gcccgagguc gugaauaacu      720

ucacccccau ccugcaggac ugcaucaaga acaucgaccg cuacgcccuc gacgaccuca      780

agagcaaggc gcuguucaac guccuggcag ccccgacaua cgacaucacc gaguaccucc      840

gggccacuaa ggagaagccc gagaacaccc ccugguacgg gaagaucgac ggcuucauca      900

acgagcugaa gaaacucgcc cuguacggga agaucaacga caacaacucc uggaucaucg      960

acaacggcau cuaccacauc gcgccccugg ggaagcucca cagcaacaac aagaucggca     1020

ucgagaccuu gaccgagguc augaaggugu acccguaccu guccaugcag caccuccaaa     1080

gcgccgacca gaucaagcgc cacuacgacu ccaaggacgc cgagggcaac aagauccccc     1140

uugacaaguu caagaaggag gggaaggaga aauacugccc caagacguac accuucgacg     1200

acggcaaggu gaucaucaag gccggggccc gggucgagga ggagaaggug aagcgguuau     1260

acugggcguc aaaagaggug aacagccagu ucuuccgggu cuacggcauc gacaagcccc     1320

ucgaggaggg caacccggac gacauccuga ccauggugau cuacaacucc cccgaggagu     1380

acaagcugaa cagcgugcuc uacggguacg acacaaacaa cggcggaaug uacaucgagc     1440

ccgagggcac guucuucacg uacgagcgcg aggcccagga guccaccuac acccuggagg     1500

agcuguuccg gcacgaguac acgcacuacc uccaggggag auacgccguc cccggccagu     1560

ggggccgcac caagcuguac gacaacgacc ggcugaccug guacgaggag ggaggggccg     1620

agcuguucgc cgggagcacc cgcacguccg gcauccugcc gcgcaagagc aucguuucca     1680

acauccauaa caccacccgg aacaacagau acaagcugag cgacaccguc cacuccaagu     1740

acggggcgag cuucgaguuu uacaacuacg ccuguauguu cauggacuac auguacaaca     1800

aggauauggg cauacucaac aagcugaacg accuggccaa gaauaacgac guggacggcu     1860

acgacaacua cauccgcgac cugucaagca acuacgcccu caacgacaag uaccaggacc     1920

acaugcagga gcggaucgac aacuacgaga accugacggu gcccuucguc gcggacgacu     1980

accuggugcg ucacgccuac aagaacccca acgagaucua cucugagauc agugaggugg     2040

ccaagcucaa ggacgccaag ucagagguca agaaguccca guacuucagc accuucaccc     2100

ugcgggggag cuauaccggc ggggccucca agggcaagcu ggaggaccag aaggccauga     2160

acaaguucau cgacgacagc cucaagaagc uggacaccua cagcuggucc ggguacaaga     2220

cgcugaccgc guacuucacc aacuacaagg uggauagcuc caaccgcgua accuacgacg     2280

ucguguucca cggcuaccuc cccaacgagg gcgacagcaa gaacucccug ccguacggga     2340

agaucaacgg cacguacaag gggaccgaga aggagaaaau caaguucagc uccgagggcu     2400

ccuucgaccc cgacggcaag aucguguccu acgaguggga cuucggggac ggcaacaaga     2460

gcaacgagga gaaccccgaa cacuccuacg acaaggucgg gaccuacacc gugaagcuga     2520

aggugacgga cgacaagggc gagagcuccg ucucuaccac caccgccgag aucaaggacc     2580

ucuccgagaa caagcugccc gugaucuaca ugcacgugcc caagucaggg gcccugaacc     2640

aaaaggucgu guuuuacggc aagggcacgu acgaccccga cggguccaua gccggcuacc     2700

agugggacuu cggggacggc agcgacuuca gcuccgagca gaaccccagc cacguguaca     2760

ccaagaaggg ggaguacacc gucacccuca gggugaugga cuccagcggc cagauguccg     2820

agaagacgau gaagaucaag aucaccgauc cgguguaccc caucggcacc gagaaggagc     2880

cgaacaacag caaggagacc gcguccgggc ccaucguccc gggcaucccc gugagcggga     2940

cgaucgagaa caccuccgac caggacuacu ucuacuucga cgugaucacc cccggcgagg     3000

ucaagaucga uaucaacaag cugggguacg gcggcgccac cuggguggug uacgacgaga     3060

acaacaacgc cgucagcuac gcuacggacg acgggcagaa ccuguccggc aaguucaagg     3120

ccgacaagcc cgggcgguac uacauccacc ucuacauguu caacggcagc uacaugccgu     3180

accggaucaa caucgagggg uccguaggcc gaugaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  4742
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt11)

<400>  4742
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uacuauucgc cugccuccuc ggcgccgccu      120

ucgccaugcc ccuacccccc caccccggcc accccggcua caucaacuuc ucauacgaag      180

uccucacccc ccucaaaugg uaccaaucaa uccgcccccc cuaccccucc uacggcuacg      240

aacccauggg aggcuggcuc caccaccaaa ucauccccgu ccucucccaa caacaccccc      300

ccacccacac ccuccaaccc caccaccaca uccccgucgu ccccgcccaa caacccguca      360

ucccccaaca acccaugaug cccguccccg gccaacacuc aaugaccccc auccaacacc      420

accaacccaa ccuccccccc cccgcccaac aacccuacca accccaaccc guccaacccc      480

aaccacacca accaaugcaa ccccaacccc ccguccaccc caugcaaccc cucccccccc      540

aacccccccu accccccaug uuccccaugc aaccccuccc ccccaugcuc cccgaccuca      600

cccucgaagc cuggcccucc accgacaaaa ccaaacgcga agaagucgac uaaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  4743
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt11)

<400>  4743
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccccucaaau gguaccaauc cauccgcccc cccuaccccu      180

ccuacggcua cgaacccaug ggcggcuggu aaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  4744
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt11)

<400>  4744
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccccucaaau gguaccaauc cauccgcccc ccccccaugc      180

uccccgaccu cacccucgaa gccuggcccu ccaccgacaa aaccaaacgc gaagaagucg      240

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  4745
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt11)

<400>  4745
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccaa accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca ccccccucaa augguaccaa uccauccgcc      240

cccccuaccc cuccuacggc uacgaaccca ugggcggcug guaaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  4746
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt11)

<400>  4746
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccua cuccucuccg      120

gcgcccucgc ccucacccaa accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca ccccccucaa augguaccaa uccauccgcc      240

ccccccccau gcuccccgac cucacccucg aagccuggcc cuccaccgac aaaaccaaac      300

gcgaagaagu cgacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  4747
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt11)

<400>  4747
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccucguc ggcgccgccu      120

ucgcaaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc acucaaaugg uaccaaucca ugauccgccc acccuacuca uccuacggcu      240

acgaaccaau gggcggcugg cuccaccacc aaaucauccc cgucguaucc caacaacacc      300

cccucaccca cacccuccaa ucccaccacc acauccccgu cguccccgca caacaacccc      360

gcguccgcca acaagcccuc augcccgucc ccggccaaca auccaugacc cccacccaac      420

accaccaacc caaccucccc cuccccgccc aacaacccuu ccaaccccaa cccguccaac      480

cccaacccca ccaacccaug caaccccaac ccccagucca acccaugcaa ccccuccucc      540

cccaaccccc ccuccccccc auguucccac uccgaccccu cccccccauc cuacccgacc      600

uccaccuuga agccuggccc gccaccgaca aaaccaaaca agaagaaguc gacuaaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  4748
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt11)

<400>  4748
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccccucaaau gguaccaauc caugauccgc ccccccuacu      180

ccuccuacgg cuacgaaccc augggcggcu gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4749
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt11)

<400>  4749
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccccucaaau gguaccaauc caugauccgc ccccccccca      180

uccuccccga ccuccaccuc gaagccuggc ccgccaccga caaaaccaaa caagaagaag      240

ucgacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4750
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt11)

<400>  4750
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccaa accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca ccccccucaa augguaccaa uccaugaucc      240

gcccccccua cuccuccuac ggcuacgaac ccaugggcgg cugguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4751
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt11)

<400>  4751
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccaa accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca ccccccucaa augguaccaa uccaugaucc      240

gccccccccc cauccucccc gaccuccacc ucgaagccug gcccgccacc gacaaaacca      300

aacaagaaga agucgacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4752
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt11)

<400>  4752
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugucuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaaaca ugauccgaca ccccuacacc uccuacggcu      240

acgaacccau gggcggcugg cuccaccacc aaaucauccc cgucgucucc caacaaaccc      300

cccaauccca cgcccuucaa ccccaccacc acauccccau gguccccgcc caacaacccg      360

gcauacccca acaacccaug augccccucc cuggccaaca cuccaugacc cccacccaac      420

accaccaacc caaccucccc cuccccgccc aacaacccuu ccaaccccaa cccguccaac      480

cccaacccca ccaaccccuc caaccccaau cccccaugca ccccauccaa ccccuccucc      540

cccaaccacc ccuacccccc auguucucca ugcaaucccu ccuccccgac cucccccucg      600

aagccuggcc cgccaccgac aaaacaaaac gugaagaagu cgacuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4753
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt11)

<400>  4753
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccccucaaau gguaccaaaa caugauccgc caccccuaca      180

ccuccuacgg cuacgaaccc augggcggcu gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4754
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt11)

<400>  4754
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccccucaaau gguaccaaaa caugauccgc caccccuccc      180

uccuccccga ccucccccuc gaagccuggc ccgccaccga caaaaccaaa cgcgaagaag      240

ucgacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4755
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt11)

<400>  4755
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccaa accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca ccccccucaa augguaccaa aacaugaucc      240

gccaccccua caccuccuac ggcuacgaac ccaugggcgg cugguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4756
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt11)

<400>  4756
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccaa accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca ccccccucaa augguaccaa aacaugaucc      240

gccaccccuc ccuccucccc gaccuccccc ucgaagccug gcccgccacc gacaaaacca      300

aacgcgaaga agucgacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4757
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt11)

<400>  4757
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggaua caucaacuuc uccuacaucc      180

gacaccccua caccuccuac ggcuacgaac ccaugggcgg cuggcuccac caccaaauca      240

uccccgucgu cucccaacaa accccccaau cccacgcccu ccaaccacac caccacaucc      300

ccaugguccc cgcccaacaa cccggcaucc cccaacaacc caugaugccc cuccccggcc      360

aacacuccau gacccccacc caacaccacc aacccaaccu cccccuuccc gcccaacaac      420

ccuuccaacc ccaacccguc caaccccaac cccaccaacc ccuacaaccc caauccccca      480

ugcaccccau ccaaccccuc cucccccaac ccccccuacc ccccauguuc uccaugcaau      540

cccuccuccc cgaccucccc cucgaagccu ggcccgccac cgacaaaacc aaacgcgaag      600

aagucgacua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  4758
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt11)

<400>  4758
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuucgc cugccuccuc ggcgccuccc      120

ucgccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacacc ccucaaaugg uaccaaaaca ugauccgcca ccccuacacc uccuacggcu      240

acgaacccau gggcggcugg cuccaccacc aaaucauccc cgucgucucu caacaaacac      300

cccaauccca cgcccuccaa ccccaccacc acauccccau gguccccgcc caacaacccg      360

gcauacccca acaacccaug augccccucc ccggccaaca cuccaugacc cccacccaac      420

accaccaacc caaccucccc cuccccgccc aacaacccuu ccaaccccaa cccguccaac      480

cccaacccca ccaaccccuc caaccccaau cccccaugca ccccauccaa ccccuacucc      540

cccaaccacc ccuaccaccc auguucucca ugcaaucccu ccuccccgac cucccccucg      600

aagccuggcc cgccaccgac aaaaccaaac gcgaagaagu cgacuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4759
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt11)

<400>  4759
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaaaca ugauccgcca ccccucccuc cuccccgacc      240

ucccccucga agccuggccc gccaccgaca aaaccaaacg cgaagaaguc gacuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  4760
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt11)

<400>  4760
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggagccgccu      120

ucuccaugcc ccuacccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

accuuuaccu cgaagccauc cgcaucgacc gcaccgccuu cguccucacc ccccuaaaau      240

gguaccaaaa caugauccgc caccccuaca ccuccuacgg cuacgaaccc augggcggcu      300

ggcuccacca ccaaaucauc cccgucgucu cccaacaaac cccccaaucc cacgcccucc      360

aaccccacca ccacaucccc augguccccg cccaacaacc cggcaucccc caacaaccca      420

ugaugccccu ccccggccaa cacuccauga cccccaccca acaccaccaa cccaaccucc      480

cccuccccgc ccaacaaccc uuccaacccc aacccguaca accccagccc caccaacccc      540

uucaacccca aucccccaug caccccaucc aaccccuccu cccccaaccc ccccuacccc      600

ccauguucuc caugcaaucc cuccuccccg accucccccu cgaagccugg cccgccaccg      660

acaaaaccaa acgcgaagaa gucgacuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  4761
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt11)

<400>  4761
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaccugga uccucuucgc cugccuccuc ggcgcagccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc ccuaaaaugg uaccaaaaca ugauccgcca ccccacaccc caaucacacg      240

cccuccaacc ccaccaccac auccccaugg uccccgcaca acaacccggc aucccccaac      300

aacccaugau gccccucccc ggccaacacu ccaugacacc cacccaacac caccaaccca      360

accuaccccu ccccgcccaa caacccuucc aaccccaacc cguccaaccc caaccccacc      420

aaccccucca accccaaucc cccaugcacc ccauccaacc ccuccucccc caaccccccc      480

ucccacccau guucuccaug caaucccucc uccccgaccu cccacucgaa gccuggcccg      540

ccaccgacaa aaccaaacgc gaagaagucg acuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  4762
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt11)

<400>  4762
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuacccc cacaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccacucaaau gguaccaaaa caugauccgc caccccuaca      180

ccuccuacgg cuacgaaccc augggcggcu ggcuccacca ccaaaucauc cccgucgucu      240

cccaacaaac cccacaaucc cacgcccucc aaccccacca ccacaucccc augguccccg      300

cccaacaacc cggcaucccc caacaaccca ugaugccccu ccccggccaa cacuccauga      360

cccccaccca acaccaccaa cccaaccuac cccuccccgc ccaacaaccc uuccaacccc      420

aaccagucca accccaaccc caccaacccc uccaacccca aucccccaug cacccaaucc      480

aaccccuacu cccccaaccu ccccuaccac ccauguucuc caugcaaucc cuccuccccg      540

accucccccu cgaagccugg cccgccaccg acaaaaccaa acgcgaagaa gucgacuaag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  4763
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt11)

<400>  4763
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaggaguug cccgccuacc acuacuacua ggucuccucu      120

uacucccgcg acccggccgc ccacucgacc uagcagacua cacauacgac cucgcagaag      180

aagacgacuc agaaccacua aacuacaaag aucccugcaa agccgcggca uuccucggag      240

acauagcccu ggacgaagaa gaucuacgag cauuccaggu ccaacaagca guagaccucc      300

ggcgacacac agcucgcaaa ucguccauca aagcggccgu cccaggcaac acaaguaccc      360

cuuccugcca guccaccaac ggucaacccc aacggggagc cugcggacgc uggcguggca      420

ggucacgauc ccggcgagca gccaccagca gaccggaacg aguauggccc gacgggguca      480

ucccauucgu aaucgguggg aacuucacgg gaucgcaacg agcaguauuc cgacaggcca      540

ugcgccacug ggaaaaacac acaugcguca ccuuccucga acgcacagac gaagacagcu      600

acauagucuu cacauacaga ccaugcggau gcugcaguua cgucggacgg agaggcggcg      660

gcccgcaagc aauaucgaua gggaaaaacu gcgacaaauu cggcauaguc guccacgaac      720

uagggcaugu cguaggguuc uggcacgagc acaccaggcc cgaccgagac cgccacguaa      780

gcauaguccg cgaaaacauc caacccggac aggaauacaa cuuccucaag auggaacccc      840

aagaagucga gucgcugggg gaaacauacg acuucgacuc cauaaugcac uacgcccgaa      900

acaccuucag ccgagguauc uuccucgaca caaucguccc caaguacgaa gucaacggcg      960

ucaaaccccc aauaggccaa cggacccgac ucucaaaagg ugacaucgcu caggcccgca     1020

aacuguauaa gugccccgcc uguggggaga cccuacagga cagcacgggc aacuucagcu     1080

ccccugaaua ccccaacggc uacagcgcac acaugcacug cgucuggcgc aucaguguca     1140

ccccaggaga gaaaaucauc cucaacuuca ccucacucga ucucuaccga agcagacucu     1200

guugguacga cuacguggag guccgagacg gguucuggcg caaagcaccg cuccgcggcc     1260

gcuucugcgg cucuaaacuu cccgaaccca uugucagcac cgacucgaga cucugggucg     1320

aguucaggag uuccagcaac uggguaggca aaggauucuu ugcagucuac gaagccauau     1380

gcggcggcga cgucaagaaa gacuacggcc acauccaguc cccaaacuac ccagacgacu     1440

accgccccuc caaagucugc auauggagga uacaaguauc agaaggguuu cacgucggac     1500

ugacauucca aaguuucgaa auagaacguc acgacucaug cgcguacgac uaccuggaag     1560

uacgcgacgg ccauuccgaa agcagcacac uaauaggccg guacuguggc uacgaaaagc     1620

ccgacgacau aaaaucaaca ucaagcagac uguggcuaaa guucgucucg gacggaagca     1680

uaaacaaagc aggauucgca gugaacuucu uuaaggaagu cgacgaaugu ucgcgcccaa     1740

acaggggagg cugcgaacaa agaugccuua acacacuggg gucauauaag ugcagcugcg     1800

accccggaua cgagcuugca ccagacaagc gaagauguga ggccgccugc ggaggcuucc     1860

ucacaaaacu gaacggaucc aucacaucac ccggauggcc aaaagaguau cccccgaaua     1920

aaaacugcau auggcagcua guagcgccaa cccaauaccg gaucagccuc caguucgacu     1980

ucuucgaaac cgaaggcaac gacgugugca aauacgacuu cgucgaggua cgcagcgguc     2040

uuaccgcgga cucaaaacug cacggcaaau ucugcggcag cgaaaaacca gaaguaauca     2100

ccagccaaua caacaacaug agagucgaau uuaaaucaga caacaccgua uccaagaaag     2160

gcuucaaagc ccacuucuuu uccgauaaag acgaaugcag uaaagauaac gggggcuguc     2220

agcaagacug cguuaacaca uucggaagcu acgaauguca augccgcagu ggguucgugc     2280

ugcacgacaa caaacacgac ugcaaagaag caggaugcga ccauaaaguc accagcacaa     2340

gcggaacgau cacuagcccc aacuggccgg acaaauaccc auccaagaaa gaaugcacau     2400

gggccaucuc cagcaccccc ggccaccgcg ucaaauuaac auucauggag auggacaucg     2460

aaucacaacc cgaaugcgcc uacgaccacc uggagguauu cgacggccga gacgccaaag     2520

caccagugcu cggccgcuuc ugcggcucca agaaaccaga accagugcua gccaccggca     2580

gucgaauguu ccuccgcuuc uacagugaca acaguguaca acgaaaagga uuccaagcaa     2640

gccacgcaac agaaugcggu ggccaagucc gggccgacgu caaaacaaaa gaccuauacu     2700

cacaugcuca auucggugac aacaacuacc cgggcggugu agacugcgaa ugggucaucg     2760

ucgcagaaga gggauacggg gucgaacucg uguuccaaac auucgaaguc gaggaagaga     2820

cagauugugg cuacgacuac auggaacucu ucgacgggua cgacagcacc gcccccagac     2880

uaggccgcua cuguggauca gguccacccg aagaagucua cagcgccggu gacucaguac     2940

ucgugaaauu ccacagcgac gacacaauua caaagaaagg cuuccaccua agauacacgu     3000

ccaccaaauu ccaggacacc cuccacagcc gcaaaugagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  4764
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt11)

<400>  4764
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgccggca cccguugccu ccuugcccuc cuccuacccc      120

aaguccuacu aggcggagca gccggccucg uccccgaacu cggccgccgc aaauucgccg      180

ccgccucauc cggacgcccc uccucacaac ccagcgacga aguacucuca gaauucgaac      240

uucgucuacu cuccauguuc ggccucaaac aacgacccac ucccucccgc gacgcagucg      300

uccccccuua caugcuagac cuuuaccgcc gccacuccgg ccaacccgga ucacccgccc      360

ccgaccaucg ccucgaaaga gccgccuccc gagccaauac cguccgcuca uuccaccacg      420

aagaaucacu cgaagaacua cccgaaacca gcggaaaaac aacacgcaga uucuucuuca      480

accucuccag cauccccacc gaagaauuca ucaccuccgc cgaacuacaa guauucagag      540

aacaaaugca ggacgcccuc ggcaacaacu ccagcuucca ccaccgcauc aacauauacg      600

aaauaaucaa acccgccaca gcuaacucca aguuccccgu cacacgccua cucgacaccc      660

gccuagucaa ccaaaaugcc ucccgcuggg aauccuucga cgucaccccc gccgucaugc      720

gauggaccgc acaaggccac gccaaucacg gcuucgucgu agaaguugca caccuagaag      780

aaaaacaagg cgucuccaaa cgccacgucc gcaucuccag aucccuacac caagacgaac      840

acucaugguc ccaaauccgc ccccuccuag ucaccuucgg acaugacggc aaaggacacc      900

cgcuccacaa acgcgaaaaa cgccaagcca aacacaaaca acgcaaacgc cucaaaucau      960

ccugcaaacg ccacccacuc uacguagacu ucuccgacgu aggauggaac gacuggauag     1020

ucgcaccccc aggcuaccac gcauucuacu gccacggaga augcccauuc ccacuugccg     1080

accaccucaa cuccaccaac cacgcuaucg uacaaacacu cgucaacucc gucaacucaa     1140

aaaucccaaa agcaugcugc guccccacag aacucucagc caucuccaug cucuaccucg     1200

acgaaaacga aaaggucguc cuaaaaaacu accaagacau ggucgucgaa ggcugcggcu     1260

gccgcuaggg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  4765
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt11)

<400>  4765
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaccgggca accgcaugcu cauggucguu cuccugugcc      120

aaguccuacu cggcggcgca agccacgccu cacucauccc cgaaacuggg aaaaaaaaag      180

ucgccgaaau ccaaggccac gccggcggaa gacgcuccgg ccaaucacac gaacuccucc      240

gcgacuucga agccacccua cuacaaaugu ucggccuccg ccgccgccca caacccucaa      300

agagcgccgu cauccccgac uacaugcgcg accuauaccg acuccaaucc ggcgaagaag      360

aagaagaaca aauccacucc accggacucg aauaccccga acgccccgcc ucccgagcaa      420

acaccguacg uucuuuccac cacgaagaac accucgaaaa uauccccggc accuccgaaa      480

acuccgcauu ccgcuuccua uucaaccucu ccuccauccc cgaaaacgaa guaaucucau      540

ccgcagaacu ccgccuauuc cgcgaacaag ucgaccaagg ccccgacugg gaaagaggcu      600

uccaccgaau aaacauuuac gaagucauga aacccccagc cgaagucgua cccggccacc      660

ucaucacacg acuucucgac acacgccuag uccaccauaa cguaacucgc ugggaaaccu      720

ucgacguaag ccccgccguc cuccgaugga cccgugaaaa acagcccaac uacggccucg      780

caauugaagu cacccaccuc caccaaacac gcacacacca aggccaacau guccgcauau      840

cccgaucacu cccacaaggc uccggcaacu gggcccaacu ccguccacuc cucguuaccu      900

ucggccauga cggacgcggu cacgcccuca ccagacgccg cagggccaaa cgauccccca      960

aacaucacuc ccagcgcgcu cguaaaaaaa acaaaaacug ccgccgccau ucccuauacg     1020

uagacuucuc cgacgucggc uggaacgacu ggauagucgc accccccgga uaccaagccu     1080

ucuacugcca cggcgacugc cccuucccac ucgcagacca ccuaaacuca accaaucacg     1140

ccaucguaca aacccucgua aacucaguca acuccuccau ucccaaagcc ugcugcguac     1200

ccaccgaacu auccgccauc uccaugcucu accuagacga auacgacaaa gucguccuca     1260

aaaacuacca agaaaugguc gucgaaggcu gcggcugccg auagggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  4766
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt11)

<400>  4766
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgggcuag gccgacgagc acaauggcua ugcugguggu      120

ggggccuacu augcucaugc ugcggaccac cuccccuacg cccaccccug cccgcagccg      180

cugccgcagc ugccggcggc caacuacuag gcgacggcgg cucacccggc cgaacagaac      240

aacccccucc cucuccccaa uccucauccg gauuccuaua ccgcagacuc aaaacccaag      300

aaaaacgcga aaugcaaaaa gaaauccuau caguacucgg ccugccacau agacccagac      360

cccuccacgg acuccaacaa ccccaaccuc ccgcccugcg ucaacaagaa gaacaacaac      420

aacaacagca acuaccccgc ggcgaacccc cacccggccg ccuaaaauca gcaccccuau      480

uuaugcucga ccuuuacaac gcccucucug ccgacaauga ugaagacggc gccuccgaag      540

gugaacgcca acaauccugg ccccacgaag ccgccucauc aucacaacga cgacaacccc      600

cacccggcgc cgcccaccca cucaaccgaa aaucccuucu cgcccccgga ucugguuccg      660

ggggcgcuuc cccacucacc uccgcacaag acagcgccuu ccuaaacgac gccgacaugg      720

uuaugucauu cguaaaccua gucgaauacg acaaagaauu uucacccaga caaagacacc      780

auaaagaguu caaauucaac cucucccaaa ucccagaagg cgaagucgua acagccgccg      840

aguuccgaau cuacaaagac ugcgucaugg gauccuucaa aaaccaaacc uuccuaauaa      900

gcaucuacca aguacuacaa gaacaccaac accgugacuc cgaccucuuu cuucuagaca      960

cccgaguagu cugggccuca gaagaagguu ggcuugaguu cgacaucacc gccaccagca     1020

accuaugggu agucacaccc caacacaaca ugggacugca acuaucaguc guaacccgcg     1080

acggcguaca cguucacccc cgagcagccg gacucguagg ucgcgacgga cccuacgaca     1140

aacaacccuu cauggucgcc uucuuuaaag ucuccgaagu acacguccga acaacacgau     1200

ccgcaucauc ccgccgccgc cagcaauccc ggaaccgauc aacacaaucc caagacgucg     1260

cccgcgucag cucggcuucg gacuacaacu ccagcgaacu aaaaacagca ugccgcaaac     1320

acgaacuaua cgucuccuuu caagaccucg gauggcaaga cuggaucauc gcacccaaag     1380

gauacgcagc aaacuacugc gacggagaau gcuccuuccc ccuaaaugca cacaugaacg     1440

caaccaacca cgccaucguc caaacccucg uccaccuaau gaaccccgaa uauguaccca     1500

aacccugcug cgccccaacc aaacuaaacg caaucucagu acucuacuuc gacgacaacu     1560

ccaacguaau ccucaagaaa uaccgcaaca ugguuguccg ugccugcgga ugccacuaag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  4767
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt11)

<400>  4767
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacguccgau cacuacgcgc cgcagcccca cacuccuucg      120

uagcacucug ggcaccccua uucuuacucc gcuccgcacu agccgacuuc ucccucgaca      180

acgaagucca cucgagcuuc auccaccgcc gccuacgguc ccaagaaaga cgcgaaaugc      240

aacgcgaaau ccucucaauu cuaggacucc cccaccgccc ccgcccccac cuccaaggca      300

aacacaacuc ugcccccaug uucaugcucg accucuacaa cgccauggca guagaagaag      360

gaggcggacc cggcggccaa ggcuucucau accccuacaa agccguuuuc ucaacccaag      420

gcccgccccu cgcaucccuc caagacucac acuuccuaac cgacgccgac augguaaugu      480

cauucgucaa ccucguagaa caugacaaag aauucuucca cccccgcuau caccaccgcg      540

aauuccgauu cgaccucucg aaaauacccg aaggcgaagc cgugaccgca gccgaauucc      600

gcauauacaa agacuacauc cgcgaacgcu ucgacaacga aacauuccgc aucuccgucu      660

accaagugcu ccaagaacac cucggccgcg aaagcgaccu cuuccuacuu gacucccgca      720

cacuuugggc cucugaagaa gguuggcucg uauucgacau aacagccacc ucaaaccacu      780

ggguagucaa cccccgucac aaccuaggac uccagcuauc aguagaaaca cucgacggcc      840

agagcaucaa ccccaaacuu gcgggacuca ucggccgcca cggaccacaa aacaagcagc      900

ccuucauggu cgccuucuuu aaagccaccg aaguacauuu cagauccaua cgcuccaccg      960

gguccaaaca acgaucacaa aaccgaucca aaaccccaaa aaaccaagaa gcucuacgaa     1020

uggcaaacgu agcugaaaac agcuccucag accaacgcca agccugcaaa aaacacgaac     1080

ucuacgucuc cuuccgagac cucggcuggc aagacuggau caucgcccca gaaggcuacg     1140

cagcauacua cugcgaaggc gaaugcgccu ucccccuuaa cucuuacaug aacgccacca     1200

accacgcaau cguccagacc cucguacacu ucaucaaccc cgaaacuguc cccaaacccu     1260

gcugcgcccc cacccaauua aacgcaaucu ccguccucua cuucgacgac uccucgaacg     1320

ucauacucaa aaaauaccga aacauggucg uccgcgccug cggcugccau uaaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  4768
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt11)

<400>  4768
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagccuccg ccgcccuccu cugccuccuc cucaccgccg      120

ccgccuucuc cccccaaggc cuagcccaac ccgucggcau caacaccucc accaccugcu      180

gcuaccgauu caucaacaaa aaaaucccca aacaacgccu cgaauccuac cgccgcacca      240

ccuccucaca cugcccccgc gaagccguca ucuucaaaac caaacucgac aaagaaaucu      300

gcgccgaccc cacccaaaaa uggguccaag acuucaugaa acaccucgac aaaaaaaccc      360

aaacccccaa acucuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  4769
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt11)

<400>  4769
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucacgc ugaucaucuu auuaccgguc gucaguaaau      120

uuagcuuugu aucacugagc gcaccccaac acuggucaug cccagagggc acuuuggcag      180

ggaacggcaa uucgacgugc guaggaccag ccccauuccu gaucuucagc cacggaaaua      240

gcaucuuccg aaucgacaca gaaggaacga acuaugagca acucguaguc gacgcagggg      300

uaucgguuau cauggacuuc cauuacaacg agaaaagaau auacuggguc gaccuagaac      360

gacagcuccu gcaaagggua uuccugaacg gcucgcggca ggaacgggua ugcaacauag      420

agaaaaacgu cagcggcaug gccauaaacu ggaucaacga agaagugauc ugguccaacc      480

aacaggaagg caucauaacc gucacugaca ugaaaggaaa caacagccac auccuccuau      540

cagcgcuaaa guaccccgcc aaugucgcgg ucgacccagu agaacgguuc auuuucuggu      600

ccuccgaagu agcugggagc cuuuaccgcg cagaccuaga cggcgucgga guaaaagcac      660

uacuugaaac auccgagaaa auaacagcag uaucccuuga cguccuagac aagcgccucu      720

ucuggauaca auacaaucgc gaagggucua acagccucau cugcaguugu gacuaugacg      780

gcgggagcgu acacaucuca aaacacccaa cacaacauaa ucuauucgcg augagccucu      840

ucggugacag aauauucuac ucaaccugga agaugaaaac aauauggaua gccaacaaac      900

acacaggcaa agacaugguc cgcaucaacc uccacagcuc cuucguaccc cucggcgaac      960

uaaaaguagu gcacccccua gcccagccca aagccgaaga ugauacgugg gaacccgaac     1020

aaaagcugug caaacugcgc aaagggaacu gcagcaguac cguuugcggu caagacuuac     1080

agucucaccu cugcaugugc gcugaggggu acgcccuuuc gagagacaga aaauacugcg     1140

aggacgucaa cgaaugcgcc uuuuggaacc acggcugcac acuuggcugc aaaaauacac     1200

cgggaagcua cuacugcaca ugucccguag gauucguccu ucuacccgau ggaaagcgcu     1260

gccaccaacu ggucucgugu ccucgcaacg ucucggaaug cagccaugac ugcguacuaa     1320

ccuccgaagg uccacuaugc uucugcccag aggguucagu ucuagagcgg gacggcaaga     1380

caugcagugg augcucaucc ccagacaacg gcggaugcuc ccaacuaugc gucccacuga     1440

gcccggucuc augggaaugc gacugcuucc cuggguacga ccuccagcuu gaugaaaaau     1500

caugcgcugc cuccgggccc cagcccuucc uacucuucgc caacucgcaa gacauaagac     1560

auaugcacuu cgacggcaca gauuacggga cccugcuguc ccaacagaug ggcaugguau     1620

acgcacucga ccacgaccca guggaaaaua aaaucuauuu cgcccacaca gcccuuaagu     1680

ggaucgaacg cgccaacaug gacggcagcc aaagagaacg gcucauagaa gagggggugg     1740

acgugccaga gggccucgcu gucgacugga uagggcgccg guucuacugg acagaccggg     1800

gcaaaagccu cauaggcaga ucagaccuca acgggaaaag gagcaagauc auaacgaaag     1860

agaauaucuc gcaaccccgc ggaaucgccg uccacccaau ggcaaaaaga cuauucugga     1920

cagauacggg aauaaacccc cggaucgaga gcuccucccu acaagggcuc gggcgguuag     1980

uaaucgccuc cagcgaccua auauggccca gcgggauuac caucgacuuc cuaacagaca     2040

aacucuacug gugcgacgca aaacaauccg ucaucgaaau ggccaaucua gacgguagca     2100

aacgacgccg acucacacaa aacgacguag gccaucccuu ugcggucgcc gucuucgagg     2160

acuacgucug guucucugau ugggccaugc ccucagucau gcgagucaac aagcgcacgg     2220

gaaaggaucg agugaggcuc cagggcucga uguugaaacc aagcagccua guagucgucc     2280

acccacuggc aaaaccaggc gcagacccau gccuauacca gaacgggggc ugugagcaca     2340

ucuguaaaaa gagacuagga accgcauggu gcucaugcag ggaaggguuc augaaagcgu     2400

ccgacggcaa aaccugccuu gccuuagacg gacaccaacu ccuagcagga ggcgaaguug     2460

accuuaaaaa ccaaguaacg ccguuagaua uccucagcaa aacaagggua agcgaggaua     2520

acaucaccga gucacagcac augcucgugg cagaaauuau ggugucagac caagacgacu     2580

gcgcacccgu aggcugcucu auguacgcaa gaugcauauc cgaaggcgaa gacgccacau     2640

gccagugccu gaagggcuuu gccggggacg guaaacugug cuccgacaua gaugagugcg     2700

aaaugggagu acccgucugu ccgcccgcaa gcuccaaaug cauaaacaca gaaggcggau     2760

acgugugccg gugcucagaa ggauaccaag gcgacggaau ccacugccug gacaucgacg     2820

aaugccaguu aggugaacau ucgugcgggg aaaacgccuc cugcacuaac accgaaggag     2880

gcuacacaug caugugcgcc ggacgucuga gcgaacccgg gcuaauaugc cccgacucca     2940

caccaccccc acacuugcgc gaggacgacc accauuacag cguacggaac agcgacagcg     3000

aaugcccccu aucacacgac ggcuacugcu uacacgacgg cgucugcaug uacaucgaag     3060

cccuagacaa auacgcgugc aacugcgugg uagguuacau aggugagcgu ugccaauacc     3120

gagaccuuaa auggugggaa cuacgccacg ccggacacgg ccaacagcag aaggucaucg     3180

ucgucgcagu augcgucgua guccucguca ugcuucuacu ccuaucacua uggggcgcac     3240

acuacuacag aacucaaaaa uuauuaagca agaaccccaa aaauccguac gaggaaucca     3300

gcagagaugu ccgcagccgg agaccggcgg acacggagga cggcaugucc ucgugcccgc     3360

aacccugguu cgucgucauc aaagaacacc aagaccugaa gaacggcggc caacccguag     3420

caggagaaga cggacaagcc gccgacggaa gcaugcaacc gaccucgugg cgacaagaac     3480

cccagcuaug cggcaugggc acugagcagg gcugcuggau uccaguaagu agugacaaag     3540

guagcugccc acaggucaug gagcgauccu uccauaugcc uucuuacgga acacaaacac     3600

uagaaggcgg uguagaaaag ccgcauucuc uccuguccgc aaacccgcuc uggcaacaac     3660

gagcacuaga uccaccccac caaauggaac ucacccaaua aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  4770
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt11)

<400>  4770
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggcc gccgcaugga aaugcucugc gccggccgcg      120

uccccgcacu ccuccucugc cucggcuucc accuccuuca agccguccuc uccaccaccg      180

ucauccccuc cugcaucccc ggcgaauccu ccgacaacug caccgcccua guccaaaccg      240

aagacaaccc acgcgucgcc caagucucca ucacaaaaug cuccuccgac augaacggcu      300

acugccucca cggccaaugc aucuaccucg ucgacauguc ccaaaacuac ugccgcugcg      360

aagucggcua caccggcguc cgcugcgaac acuucuuccu caccguccac caaccccucu      420

ccaaagaaua cgucgcccuc accgucaucc ucaucauccu cuuccucauc accgucgucg      480

gcuccaccua cuacuucugc cgcugguaca gaaaccgcaa auccaaagaa cccaaaaaag      540

aauacgaacg cgucaccucc ggcgaccccg aacuccccca agucuaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  4771
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt11)

<400>  4771
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgaaggcg aaaucaccac cuucaccgcc cucaccgaaa      120

aauucaaccu cccccccggc aacuacaaaa aacccaaacu ccucuacugc uccaacggcg      180

gccacuuccu ccgcauccuc cccgacggca ccgucgacgg cacccgcgac cgcucagacc      240

aacacaucca acuccaacuc uccgccgaau ccgucggcga aguauacaua aaauccaccg      300

aaaccggcca auaccucgcc auggacaccg acggccuccu cuacggcucc caaaccccca      360

acgaagaaug ccucuuccuc gaacgccucg aagaaaacca cuacaacacc uacaucucca      420

aaaaacacgc cgaaaaaaac ugguucguag gccucaaaaa aaacggcucc ugcaaaagag      480

gcccccgcac ccacuacggc caaaaagcca uccucuuccu cccacucccc gucucaucag      540

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  4772
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt11)

<400>  4772
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggggguag ggggagggga cguggaggac guaacgccga      120

ggccgggagg gugucagaua agcgggagag gggcgagagg gugcaacgga auaccgggag      180

cggcggcgug ggaggcggcg cugccgagga ggaggccgag gaggcacccg agcguaaacc      240

caagaagcag agcagcaggg agcccgagga cgagggggag aaggacggag gagaggccga      300

gugggagcag gcugggggau cgggggaggg ggagagcacu gccgggaggg cgacuagggg      360

gaagagggag ggggagggcg ccggagaggg ugggagggag ggggaggggg agggggacgg      420

cggcgccgag agcggcgccg gcggcgaggg ggagcaggcc gggaccggcg gggacgaugg      480

cagcggggag cauaaccacg uugccggcgc ugccggaaga uggagggagu ggggcguucc      540

caccggggca cuucaaggau ccgaagagac uguauuguaa gaauggaggg uucuuucuaa      600

ggauacaucc ggaugggaga guggaugggg ugagggaaaa gagugacccg cacauaaagc      660

ugcaguugca ggcggaggag agagggguag uaagcauaaa gggggugugc gcaaauaggu      720

aucuggcgau gaaggaggau gggaggcuau uggcgagcaa gugugugacg gacgagugcu      780

uuuucuuuga aaggcuagag agcaauaacu acaacacgua caggagcaga aaguauacga      840

gcugguaugu ggcgcugaag agaacgggac aguacaaguu agggagcaag acagggccag      900

ggcagaaggc aauauuguuc cugccaauga gugcaaagag cuagggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  4773
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt11)

<400>  4773
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uccucaccug gauccucccc acccuccucu      120

accgcuccug cuuccacauc aucugccucg ucggcaccau cucccucgcc ugcaacgaca      180

ugacccccga acaaauggcc acaaacguca acugcuccuc ccccgaacgc cacacccgcu      240

ccuacgacua cauggaaggc ggcgacaucc gcguccgccg acucuucugc cgcacccaau      300

gguaccuacg caucgacaaa cgcggcaaag uaaaaggcac ccaagaaaug aaaaacaacu      360

acaacaucau ggaaauccgc acagucgccg ucggcauagu cgcaaucaaa ggcgucgaau      420

ccgaauucua ccucgccaug aacaaagaag gcaaacucua cgccaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa cucauccucg aaaaccacua caacaccuac gccuccgcca      540

aauggaccca caacggcggc gaaauguucg ucgcccucaa ccaaaaaggc auccccgucc      600

gcggcaaaaa aaccaaaaaa gaacaaaaaa ccgcccacuu ccuccccaug gccaucaccu      660

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  4774
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt11)

<400>  4774
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuccucc ccuccguagu ccucaaacua uuccucgcag      120

ccguccuauc cgcccucguc accggcgaau cacucgaacg ccuccgccgc ggccucgccg      180

caggcacaag caaccccgac ccccccaccg ucuccaccga ccaacuccuc ccccuaggcg      240

gcggccgaga ccgcaaaguc cgcgaccucc aagaagcaga ccucgaccuc cuccgcguca      300

cccucuccuc caaaccccaa gcccuagcaa cccccaacaa agaagaacac ggcaaacgaa      360

aaaaaaaagg caaaggacua ggcaaaaaac gcgaccccug ccuccgcaaa uacaaagacu      420

ucugcaucca cggcgaaugc aaauacguca aagaacuacg cgcccccucc ugcauaugcc      480

accccggcua ccacggcgaa cgaugccacg gccuaucccu ccccguagaa aaccgacuau      540

acaccuacga ccacaccacc auccucgccg ucgucgccgu cguccucuca uccgucugcc      600

uacucguaau cguaggacuc cucauguucc gcuaccaccg ccgaggcggc uacgacgucg      660

aaaacgaaga aaaagucaaa cucggcauga ccaacuccca cuaaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  4775
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt11)

<400>  4775
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggucacua aacuacuccc cgcccuccua cugcaacacg      120

uucuccucca ccuauuacug cuccccauug caaucccaua cgccgaaggc cagcgaaaac      180

gccgcaacac gauccacgaa uuuaagaaaa gcgcaaaaac aacccuaauc aaaauagacc      240

cugcacuaaa aauaaaaacc aagaaaguca acacagcaga ccaaugcgcu aacagaugca      300

cccggaacaa aggccugccg uucacaugca aggcauucgu cuucgacaag gcccgcaaac      360

aaugccugug guucccauuc aacucaauga gcucaggcgu caagaaagag uucggacacg      420

aguucgaccu cuacgaaaac aaagacuaca uccgcaacug uaucaucgga aaaggaagau      480

ccuacaaagg cacaguauca aucaccaagu ccggcaucaa augccaaccc uggagcagca      540

ugauccccca cgaacacucc uuccucccca gcucguaccg cggcaaagac cuccaagaaa      600

acuacugccg gaacccccga ggagaagaag gcggucccug gugcuucacc uccaaccccg      660

aaguccgcua cgaagucugc gacauccccc aaugcagcga aguagaaugc augaccugca      720

acggcgaauc cuacagaggc cuaauggauc acaccgaauc cggcaagaua ugccaacgcu      780

gggaccauca aaccccacac cgccacaagu uccuacccga acgcuacccc gacaaaggau      840

ucgacgacaa cuacugccgc aacccugacg ggcaaccacg ccccuggugc uacacccuag      900

acccacacac acgaugggaa uacugcgcca ucaaaaccug cgccgauaac acaaugaacg      960

acacugacgu cccacuagaa accaccgaau gcauacaagg acaaggcgaa gguuacagag     1020

gaaccguaaa cacuauaugg aacggcauac cuugccaacg cugggacucc caauacccac     1080

acgaacacga caugacuccc gaaaacuuca aaugcaaaga ccuccgcgaa aacuacugcc     1140

gcaaucccga uggguccgaa agucccuggu gcuucaccac agacccaaac auccgcgugg     1200

gauacugcuc ccaaauuccc aacugcgaca ugucucacgg ucaagacugc uaccgaggca     1260

acggcaagaa cuacauggga aaccugucac agaccagauc cggucuaacc ugcuccaugu     1320

gggacaaaaa cauggaagac cuccacaggc acauauucug ggaacccgac gccuccaagc     1380

ucaaugaaaa cuacugcagg aaccccgacg acgacgccca cggccccugg uguuacacag     1440

gaaacccccu cauuccuugg gacuacugcc caauaucacg cugcgaaggu gacacuacac     1500

ccacaauagu caaccucgac caccccguca ucucuugcgc caaaacaaaa caacucaggg     1560

uagucaacgg aauccccacc aggacaaaca uaggcuggau ggucucccua cgguaccgca     1620

acaaacacau cugcggaggc ucacugauca aagaauccug gguccucacc gcacgccaau     1680

gcuuccccag cagagaccuc aaagacuacg aagccugguu agguauucac gacguccacg     1740

gcagagggga cgaaaaaugc aagcaagucc ucaacguaag ccagcucguc uacggacccg     1800

aaggaucgga ccucguacuc augaaacugg cccgccccgc aguacucgac gacuucgucu     1860

caacgauuga ccugccaaac uacggaugca cgaucccaga aaagacguca uguagcgucu     1920

acgguugggg cuacacgggc cucaucaacu acgacggccu ccuccgaguc gcacaccuuu     1980

auaucauggg caacgaaaaa ugcagccagc accaccgagg caaagucaca cuuaacgaau     2040

ccgaaaucug ugcaggagcc gagaaaauag gcucaggacc cugcgaaggc gacuacggcg     2100

gaccccuggu cugcgaacaa cacaaaaugc gcaugguccu uggcgucauc guacccggac     2160

gaggcugcgc cauccccaac cgccccggca uauucgucag aguugcauac uaugcaaaau     2220

ggauccauaa aaucauacua acauacaaag ucccccaguc auaaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  4776
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt11)

<400>  4776
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaaagcag cagcaauagg caucgaccua ggaaccaccu      120

acucaugcgu cggagucuuc cagcacggca aaguagaaau aaucgcuaac gaccaaggaa      180

acagaaccac gcccucguac gucgccuuca ccgacaccga acgacugaua ggggacgcag      240

caaagaacca ggucgcacuc aacccacaaa auacagucuu cgacgcaaaa agacucauag      300

gcagaaaauu cggcgacccc guagugcaaa gcgacaugaa acacuggcca uuccaaguga      360

uaaacgacgg ggacaaacca aaaguccaag ucucauacaa aggcgaaaca aaggcauucu      420

acccagaaga aaucuccagc auggucuuaa ccaaaaugaa agaaauagcc gaagcauacc      480

ucgguuaccc aguaacgaac gcagucauua caguacccgc auacuucaac gacagccaac      540

ggcaagccac gaaagacgcg ggagucauag cagggcucaa cguauuaaga auaaucaacg      600

aaccaacagc agcagccauc gcauacggcc uggaucgcac aggcaagggc gaaagaaacg      660

uacugaucuu ugaccuaggc gggggcacgu ucgacguaag cauccugacc auagacgacg      720

ggauuuucga ggucaaagca acagcagggg acacacaccu gggcggggaa gacuucgaca      780

acagacucgu gaaccacuuc guagaagagu ucaaacgcaa acacaagaaa gacaucucgc      840

agaacaaaag agcagugaga agacuacgga ccgcgugcga gcgcgcaaaa cgcacccuaa      900

gcucaagcac gcaggcgagc cuggaaauag acagccucuu cgaaggaauc gacuucuaca      960

caucuauaac aagagcgaga uucgaagaac ugugcuccga ccucuuccgc uccacgcugg     1020

agccagucga aaaagcgcuc cgggaugcga aacuggacaa agcacaaauc caugaccucg     1080

uacuggucgg aggcucgacc cgcauuccaa aagugcaaaa acuccuccag gacuucuuca     1140

acggacgaga ccucaacaaa ucaaucaacc ccgacgaagc agucgcguac ggggccgcug     1200

uccaagccgc aauccugaug ggggacaaaa gcgagaaugu gcaagaccuc cuccuccucg     1260

acguggcccc acucucgcuu ggacucgaga ccgcgggagg cguaaugaca gcacucauaa     1320

aaagaaauuc aacaauccca acaaagcaga cacagaucuu cacaacguau agcgacaauc     1380

aaccgggcgu acucauacaa guauacgagg gcgaacgcgc aaugacgaag gacaacaacc     1440

uucuaggcag auucgagcuc ucaggcauac caccagcccc acgcggggua ccgcaaauag     1500

aagugacauu cgacaucgac gcaaacggaa ucuuaaacgu aacagcgacc gauaaaucaa     1560

ccggaaaggc gaacaaaauc acaaucacaa acgacaaagg acgccuuuca aaagaagaga     1620

ucgagagaau gguacaggag gcagaaaagu acaaagcaga ggacgagguc caacgcgaaa     1680

gaguauccgc caaaaacgcc cuggaaucau acgcauucaa caugaagucc gccgucgaag     1740

acgaaggucu aaagggaaag auauccgaag ccgacaaaaa gaaaguacua gauaaaugcc     1800

aagaagucau cagcuggcuc gacgcaaaca ccuuggccga aaaagacgaa uuugaacaca     1860

aaagaaaaga acuugaacaa guaugcaauc ccauaaucuc aggccuguac caaggcgcag     1920

gcgggccagg gcccgggggc uuuggggcac aaggccccaa aggaggaagc ggaagcgggc     1980

cgacaauaga ggaaguagac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4777
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt11)

<400>  4777
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgaaagcag cagcaaucgg aaucgaccuc gguaccacau      120

acagcugcgu aggcguauuc caacacggga aaguagaaau cauagcaaac gaccaaggga      180

accggacaac ccccuccuac gucgccuuca ccgacacaga acgacuuauc ggcgacgcag      240

ccaaaaacca ggucgccuua aacccccaaa acaccgucuu cgacgcaaaa agacucaucg      300

gaagaaaauu cggggacccc gugguacaaa gcgacaugaa acacuggccc uuccaaguaa      360

ucaacgacgg agauaagccc aagguccaag uaucguacaa aggcgagacc aaagccuucu      420

acccagaaga aauaucaagc augguguuaa ccaagaugaa ggaaaucgcc gaagccuacc      480

ucggcuaccc agugacaaac gccguaauaa ccgugcccgc guacuucaau gacucccaac      540

gccaagccac gaaagacgcc ggcgucauag ccggacuaaa cguacuacgc auaauaaaug      600

aaccgacagc agccgccauc gcauacggac ucgaccgcac aggcaaaggc gaaagaaacg      660

uauugauauu cgacuuaggc ggaggcaccu ucgacgucuc gauacuaacc auagacgacg      720

gaauauucga ggucaaggcc accgccggag acacacaccu aggcggcgaa gacuucgaua      780

aucgucuagu gaaccacuuc guagaagagu ucaagcgcaa acacaagaaa gacaucuccc      840

aaaacaaacg ugcagugcga aggcuaagaa ccgcaugcga acgcgcaaaa agaacccuca      900

gcuccagcac acaagcgagc cuagaaauag acagucucuu cgaaggcauc gauuucuaca      960

ccucgauaac uagagcgcgc uucgaagaau uaugcagcga cuuauuccga ucgacauuag     1020

aaccuguaga aaaagcgcuc cgggacgcga aacuagacaa agcccaaauc cacgacuugg     1080

uccugguagg gggcucuaca aggauaccga aagugcaaaa gcuauuacaa gacuucuuca     1140

acggacgcga ucucaauaaa uccaucaacc ccgacgaggc aguagcauac ggcgccgcgg     1200

uccaggcagc gauacucaug ggagacaaau cagaaaacgu gcaagaccuc cugcuccuug     1260

acguagcacc acucucgcuc ggacuagaaa cggcgggagg ggucaugacc gcacucauca     1320

agagaaacag uaccauccca accaaacaaa cccaaaucuu caccacauac ucagacaacc     1380

aaccgggagu gcuaauccaa guauacgaag gcgaacgcgc gaugaccaaa gacaauaacc     1440

ugcuaggaag auucgaacua ucaggcauac ccccggcucc acgaggcguc ccccaaaucg     1500

aaguaaccuu cgacauagac gccaacggaa uccucaacgu gacagcgacc gacaaaagca     1560

ccgggaaagc aaacaaaauc acaaucacaa acgacaaagg acgauuaagc aaagaagaga     1620

ucgagcgaau gguccaagaa gccgaaaagu acaaagccga agacgagguc caacgcgaac     1680

gaguaagcgc caaaaacgca uuagaauccu acgcguucaa uaugaaaagc gcaguagaag     1740

acgaaggacu gaaagggaaa auaagcgaag cagacaaaaa gaaaguacuc gacaaaugcc     1800

aagaaguaau cuccuggcua gacgcaaaua cccucgccga aaaagacgag uucgaacaca     1860

aaagaaaaga acuggaacaa gugugcaacc caauuaucuc aggacuauac cagggggcag     1920

gcgggccagg acccggagga uucggcgcgc aaggaccaaa aggaggcagc ggaagcggac     1980

caacaaucga ggaaguagac uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4778
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt11)

<400>  4778
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgacagcaa agggcauagc aauaggcauc gaccucggca      120

ccacauacuc cugcguaggc gucuuccaac acggcaaagu agaaaucauc gcaaacgacc      180

aaggaaacag gacaacaccc ucauacgucg cauuuaccga caccgaaaga cuuaucggag      240

acgcggccaa aaaccagguc gcaaugaacc cccaaaauac cgucuucgac gcaaagcgac      300

ucauaggacg caaauucaau gaccccgugg uacaggcaga caugaaacua uggccguucc      360

aaguuauaaa cgaaggcgga aagccgaaag uccucguauc cuacaaaggc gaaaacaaag      420

ccuucuaccc cgaggaaauc ucgagcaugg uccuaaccaa acucaaagaa acagccgaag      480

cauuccucgg gcacccaguc accaacgcgg ucauaaccgu accagcauac uucaacgacu      540

cgcaaagaca ggcaaccaaa gacgccggag ucaucgcagg acugaacguc cuccgaauca      600

ucaacgaacc aaccgccgca gccaucgccu acggacuaga caaaggcggg caaggcgaac      660

ggcacguacu uaucuucgac cucgggggcg gaaccuucga cgucuccauc cugaccaucg      720

acgaugggau auucgaaguc aaagccacgg ccggagacac acaccucgga ggcgaagacu      780

ucgacaaccg ccuaguaagu cacuucgucg aagaguucaa acgaaaacac aaaaaggaca      840

ucagccagaa caaacgagca guacgccgcc ucaggacagc augcgaacgc gccaaaagga      900

cacuaagcuc cuccacgcaa gcaaaccucg aaauagacag ccuauacgaa ggaauagacu      960

ucuacacaag caucacaagg gccagauucg aagaacucug cgcagaccua uuccggggca     1020

cacucgaacc agucgaaaaa gcgcugcgag acgccaagau ggacaaagcc aaaauccaug     1080

acauaguccu cgucggaggc uccacccgaa uccccaaagu acaacgacuu cuacaggauu     1140

acuucaacgg aagagaucuc aauaaaucaa ucaaccccga cgaggcgguc gcauacggcg     1200

ccgccgugca ggccgcaaua cucauggggg acaaaagcga gaaaguacaa gaccuguuac     1260

uacuggaugu ggcaccccua agccucgggc uggaaaccgc cggagggguc augaccgccc     1320

ucaucaaacg aaacuccacg auccccacaa aacaaaccca aauauucacc accuacuccg     1380

acaaccagcc aggaguacua auccaaguau acgaaggaga acgcgccaug acaaaagaca     1440

acaaccuacu aggccgguuc gaucuaacag gcauaccacc ggcgccccga gggguacccc     1500

aaaucgaagu aacauucgac aucgacgcca acggcauacu gaacgugacc gcaacggaca     1560

aaucgaccgg gaaagugaac aaaauaacaa ucacaaacga caagggccgc uuaagcaagg     1620

aagaaaucga gcgcaugguc cuagacgcag aaaaauacaa agccgaagac gaaguacaac     1680

gagagaaaau cgccgcgaag aacgcgcugg aaagcuacgc auucaacaug aaaagcguag     1740

uaucagacga gggacuaaaa ggcaaaauaa gcgaaagcga caaaaacaaa auacucgaca     1800

aaugcaacga acuacuaagc uggcuagaag ucaaucaacu cgccgaaaaa gaugaguucg     1860

accacaaacg caaggaacuc gaacaaaugu gcaacccaau aaucaccaaa cuuuaccaag     1920

gaggcugcac aggcccagca ugcggaacag gcuacguacc aggccgaccu gccaccggcc     1980

ccaccauaga agaaguagac uagggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4779
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt11)

<400>  4779
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agugcgcgcg gacccgcaau cggaauagac cucggcacca      120

ccuacucaug cgugggcgua uuccagcacg gaaaagucga aauaaucgca aacgaccaag      180

ggaacagaac cacaccaucc uauguggccu uuacugacac cgaacgccua aucggagacg      240

cugccaagaa ccagguagca augaacccca caaacacaau cuucgacgca aagaggcuaa      300

ucggacgcaa guucgaagac gcaacagucc aaagcgacau gaagcacugg cccuuccgcg      360

uaguauccga aggaggcaaa cccaaggucc aagucgaaua caaaggcgag acaaagaccu      420

uuuucccaga agagaucuca agcaugguac ucaccaaaau gaaagaaaua gcggaggcau      480

aucuuggagg aaagguccac agcgcaguga uaacaguccc cgcauacuuu aacgacagcc      540

aaagacaagc aacaaaagac gcaggaacca uaacaggacu uaacguccuc cgaauaauca      600

augaaccaac agcagcagca aucgcauacg gccuagacaa gaaaggcugc gccggaggcg      660

agaaaaacgu ccuaauauuc gaccuaggcg ggggaacguu cgacgucuca auacucacca      720

uagaagacgg caucuucgag gucaaaagca cggccggaga cacacaccuc ggcggggaag      780

acuucgacaa ccgcauggug agccaucucg ccgaagaguu caaaagaaag cacaagaaag      840

auauaggccc caacaaacgg gcagugagaa ggcucaggac cgcaugcgaa cgggcgaaaa      900

gaacccucag cucaagcaca caagcaagua uugaaaucga cucccuauac gaagggguag      960

acuucuacac cucaaucaca cgggcccgcu uugaggaacu aaacgccgau cuguuccgcg     1020

gaacacuaga accagucgaa aaagcacucc gagacgcaaa auuagacaaa ggccaaauuc     1080

aagaaauagu ccuggucgga gguuccaccc gcaucccaaa aauccaaaaa cuacuacaag     1140

acuucuucaa cgggaaagaa cucaacaaau caauuaaccc cgaugaagca gucgccuacg     1200

gagcagcagu acaagcagcg auacucaucg gggacaaaag cgagaacguc caagaccuac     1260

uacugcuaga cgugacccca cucucacucg ggauagagac agcaggcgga guaaugaccc     1320

cacugauaaa acgaaacaca accauaccca caaaacagac ccagaccuuc acaaccuaca     1380

gcgacaacca gucauccgua cucguccagg uguacgaggg agaacgagca augacgaaag     1440

acaacaaccu auugggcaag uucgaccuaa cgggcauacc gcccgcgccc cgcgguguac     1500

cacaaaucga agucacuuuu gacauagacg ccaacggaau ccuaaacgug accgcggccg     1560

acaaaagcac agggaaggaa aacaagauca caauaacaaa cgacaaaggg agacugagca     1620

aagacgacau ugaccgaaug guccaagaag cagaacgcua caaaucugaa gaugaggcaa     1680

acagagaccg agucgcugca aagaacgcac uggaaucuua caccuacaac aucaagcaga     1740

ccgucgaaga cgaaaaacug cgaggaaaaa uaagcgaaca agacaaaaac aaaauacugg     1800

acaaauguca agaagucaua aacuggcucg accgaaacca aauggccgaa aaagacgaau     1860

acgaacacaa acaaaaagaa cucgaacgag uaugcaaccc cauaaucuca aaauuauacc     1920

aaggaggccc aggaggcggg agcggcggag gaggcuccgg agcgagcgga ggccccacca     1980

ucgaagaagu agauuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  4780
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt11)

<400>  4780
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucggucguag gaaucgaucu gggcuuucaa ucaugcuacg      120

uugcaguggc gagagcagga ggaaucgaaa ccauagccaa cgaauacagc gauaggugua      180

cgccggcaug caucagcuuc ggccccaaaa acagaucaau aggagcagcc gccaaaucac      240

aagucaucuc caacgcaaag aacaccguac aaggcuucaa gcgauuccau ggcagagccu      300

uuucggaccc guucgucgaa gcugaaaaau ccaacuuagc guacgacaua guucaacucc      360

caacaggauu aaccggcauc aaagucaccu acauggaaga ggagcgaaac uuuaccaccg      420

aacagguaac cgcgaugcuc cuaagcaagc uaaaggaaac cgcagaaagc guccucaaaa      480

agcccgucgu agauugcgug gucuccgucc caugcuucua cacggacgca gaacgucgca      540

gcguaaugga cgccacacaa auagccggac ucaacugccu acggcugaug aacgaaacga      600

ccgcagucgc acuggccuac gggauauaua agcaagaccu accagcgcug gaagaaaaac      660

cacguaacgu ggucuucguc gacaugggac acuccgccua ccaagucucc gugugcgcgu      720

ucaaccgcgg caaacucaaa guccucgcaa cagcguucga uaccacauug ggcggacgca      780

aguucgauga aguacucgua aaccacuucu gcgaggaguu cggcaaaaag uacaaacucg      840

acaucaaauc gaaaauacga gcacuacucc gccuuagcca agaaugugaa aaacuaaaga      900

aacugauguc agcaaacgcc agcgaccuac cacuaucaau agaaugcuuc augaacgacg      960

uagacguaag cggaacgaug aaucgcggaa aauuccugga aaugugcaac gaccuccucg     1020

cccgaguuga gccgccacua cggagcgugc ucgaacaaac caagcucaag aaagaagaca     1080

uauacgccgu agaaauaguc gggggcgcaa cccgcauccc cgccgugaaa gagaaaaucu     1140

caaaauucuu cgggaaagaa cucagcacca cacucaacgc cgacgaagcg gugacccgag     1200

gcugcgcgcu ccaaugcgca auccuaagcc ccgccuucaa aguacgagag uucuccauaa     1260

ccgacguagu ccccuauccc auaucccuua gguggaauag ccccgcagaa gaaggcagca     1320

gcgacugcga aguauucagc aaaaaccacg ccgcacccuu cucaaaagua cugaccuucu     1380

accgaaaaga accauucaca cucgaggcau acuacagcuc cccacaggac cucccauacc     1440

cagacccggc caucgcccaa uucagcguac aaaaagucac accacaaagc gacgguagcu     1500

cgagcaaagu caagguaaaa guccggguca acguucacgg cauauucuca guaagcagcg     1560

caagccucgu agaaguacac aaauccgagg aaaacgaaga acccauggaa accgaccaaa     1620

acgccaaaga agaagagaaa augcaaguag aucaagagga accacacguc gaggaacaac     1680

agcaacagac ccccgccgaa aacaaagcag aaagcgaaga aauggaaacc agccaagccg     1740

gcuccaaaga uaagaaaaug gaccaaccac cacaagccaa aaaggccaaa gucaaaacau     1800

ccacagucga ucuccccaua gaaaaccaac uacuauggca aaucgaccgc gagaugcuca     1860

acuuauacau agagaaugaa ggcaaaauga uaaugcaaga caaacucgaa aaagagagaa     1920

acgacgccaa aaacgcaguc gaagaauacg ucuacgaaau gcgagacaaa cuaagcggcg     1980

aauacgagaa auucguaucg gaagacgaca gaaacagcuu cacccuaaag cuggaggaca     2040

ccgaaaacug gcuauacgaa gacggagaag accaacccaa acaaguauac guagacaaac     2100

ucgcagaacu caaaaaccua ggccaaccca ucaaaauacg auuccaagaa uccgaggaac     2160

gccccaaauu auucgaagaa cucggcaagc aaauccaaca guacaugaaa auaauaucga     2220

gcuucaaaaa caaagaagac caauacgauc accuggacgc agcagacaug acuaaaguag     2280

aaaaaucaac aaacgaagca auggaaugga ugaacaacaa acucaaccuu caaaacaagc     2340

aaagccuuac cauggaccca guagucaaaa gcaaggaaau cgaagccaag aucaaagagc     2400

ucacaucaac cuguuccccu aucauaucaa aacccaaacc aaaaguagaa ccacccaagg     2460

aagaacagaa aaacgccgaa caaaacggcc ccgucgacgg acaaggcgac aaccccggcc     2520

cccaagccgc cgaacaaggg accgacaccg caguaccaag cgacagcgau aagaaacuuc     2580

ccgaaaugga caucgacuag ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  4781
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt11)

<400>  4781
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucagucgucg gcaucgaucu cggguuccug aacugcuaca      120

uagcagucgc ccggagugga gggaucgaga caauagcaaa cgaauacucg gaccgcugca      180

cacccgcaug cauaagccuc ggcuccagaa cgagagccau cgguaacgcc gcuaagagcc      240

aaaucguaac caacguacgc aacacaaucc acggcuuuaa gaaacuccac ggcagaucgu      300

uugacgaccc uauaguccag acagagcgca uacgacugcc cuacgaacua cagaaaaugc      360

caaacgggag cgcgggcguc aaaguccgau accuagaaga ggagcgccca uucgcaauug      420

aacaaguaac uggaaugcug cuagcaaaau uaaaagaaac gagcgaaaac gcccuaaaga      480

aacccguagc cgauugcguu aucucaauac cgagcuuuuu cacagacgca gagcggcgcu      540

cagucauggc cgcagcccaa gucgccggcc ucaacugccu ccgccucaug aacgaaacaa      600

cugccguugc ccuggccuac ggcaucuaca aacaagaccu accgccccug gacgagaaac      660

cgcgaaacgu cgucuuuauc gacaugggac acuccgcaua ccaaguucua guaugcgccu      720

ucaacaaagg caagcucaaa guacuggcaa ccacauucga ccccuaccuc gguggacgaa      780

acuucgauga agcgcucguc gacuacuucu gcgacgaguu caaaacgaaa uacaaaauca      840

acgucaagga gaacucccgg gcccugcuaa gacucuacca agagugcgaa aaacuaaaga      900

aacuuauguc ggcaaacgcc ucagaccugc cccucaacau agaauguuuc augaaugacc      960

ucgacguaag cuccaaaaug aaccgcgcac aauucgagca acuaugcgcc agccugcuag     1020

ccaggguaga accuccacua aaagcaguca uggagcaggc uaaccuacaa cgcgaggaca     1080

uaagcagcau cgagaucgug ggaggcgcca cacgcauacc cgcagucaaa gaacaaauca     1140

ccaaauuuuu ccuaaaagac aucucaacca cccucaacgc cgacgaagca guagcgcgcg     1200

gcugcgcccu ccaaugcgcg auacucagcc cagccuucaa gguacgcgag uucaguauca     1260

ccgaccucgu ccccuacuca auaacacuaa gauggaaaac cucguucgaa gacggcuccg     1320

gagaaugcga aguauucugc aagaaucacc cggcaccguu cucgaaggua aucaccuucc     1380

acaagaaaga acccuucgaa cuugaagcau ucuacacaaa ucuucacgag guaccauacc     1440

cggacgcacg cauaggcuca uucaccaucc aaaacgucuu cccccaaucc gacggcgacu     1500

caagcaaagu gaaagugaaa guccgcguaa auauccacgg aauauucucc guagcaagcg     1560

caucaguaau cgagaaacaa aaccucgaag gcgaccacag cgacgcacca auggagaccg     1620

aaaccagcuu caagaacgag aacaaggaca auauggacaa aaugcaagua gaccaggaag     1680

aaggacacca gaaaugccac gcagaacaca cccccgagga agaaaucgac cacacaggcg     1740

ccaaaacaaa auccgccgua agcgacaaac aggaucgccu aaaccagacg cucaaaaagg     1800

ggaaagugaa auccauagac cuacccaucc aguccucacu uugccgccag cuaggccagg     1860

accuucugaa cucauacauc gaaaacgagg ggaaaaugau caugcaagac aaacucgaaa     1920

aggaaaggaa ugacgccaaa aacgcagucg aagaauacgu auacgacuuc cgcgaccgac     1980

ugggcacagu auacgaaaaa uucauuacac ccgaagaccu caguaagcua agcgcggucu     2040

uggaggacac cgagaacugg cucuacgaag acggcgagga ccagcccaaa caaguauacg     2100

uggacaaacu acaagaacuc aaaaaguacg gacaaccuau ccaaaugaag uacauggaac     2160

acgaagaacg cccaaaagcu cuaaacgacc uaggcaagaa gauacagcuc guaaugaagg     2220

ucaucgaagc cuaccgcaac aaagacgaaa gauacgacca ccuagaccca accgaaaugg     2280

aaaaaguaga aaaaugcaua agcgaugcaa ugagcuggcu caacucuaag augaaugcac     2340

aaaacaaacu cucccuuacc caagacccag ucguaaaagu cucagaaauu gucgcgaaaa     2400

gcaaagagcu agacaacuuc ugcaauccca ucaucuacaa gcccaaaccc aaagcagaag     2460

uacccgaaga caaacccaaa gccaacuccg aacacaacgg cccgauggac ggccaaagcg     2520

gaaccgaaac aaaguccgac aguaccaaag acagcucgca gcacaccaag uccuccggcg     2580

aaauggaagu cgacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  4782
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt11)

<400>  4782
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuaagcc uggucgcagc aaugcugcua cuacuaagcg      120

cagcaagggc agaggaagaa gacaagaaag aggacgucgg cacaguaguc ggaauagacc      180

uggggacgac cuacagcugu guaggggucu ucaagaacgg cagaguugaa aucaucgcaa      240

acgaccaagg caaccgaaua acaccgagcu acguagcguu cacacccgaa ggcgaaagac      300

ucaucgggga cgcagccaaa aaccaacuaa caagcaaccc ggaaaacaca guguucgacg      360

ccaaaagacu aaucggcaga accuggaacg accccuccgu ccaacaagac auaaaauucc      420

ucccauucaa agugguagaa aagaaaacga aacccuacau acaagucgac auagggggcg      480

ggcagacaaa aacauucgcg ccagaagaaa ucagcgcaau gguccuaacc aaaaugaaag      540

aaacggcaga agcguaccug ggaaagaaag ucacccacgc cgucgucacg guccccgccu      600

acuucaacga cgcgcaacga caagcaacca aagacgcagg cacgaucgcg ggacugaacg      660

uaaugaggau aaucaacgaa ccaacagcag ccgccaucgc auacggacug gacaagcgcg      720

aaggagagaa aaacauacug gucuucgacc ugggcggagg aacauucgac gucucgcuac      780

ugacaauaga caacggcgua uucgaggucg uggcuacgaa cggagacaca caccuaggag      840

gggaagacuu cgaccaacga gucauggaac acuucauaaa acuauacaag aagaaaaccg      900

gaaaagacgu aagaaaagac aacagagccg uacaaaaacu gaggcgcgaa guagaaaaag      960

cgaaacgggc ccugagcucg caacaccaag cgagaauaga aauagagucc uucuacgaag     1020

gagaagacuu cagcgaaaca cuaacgcgcg ccaaauucga agaacucaac auggaccucu     1080

uccgcucaac uaugaagccc guccaaaaag ugcucgaaga cagcgaccug aaaaagagcg     1140

auaucgacga aauaguacug guaggcggaa gcacacggau cccaaaaaua cagcaacucg     1200

ugaaagaguu cuucaacgga aaagaaccau cgcgagggau caacccagau gaagcggucg     1260

cauacggugc agcgguccag gccgggguac uaagcggaga ccaagacaca ggagaucugg     1320

uacuccuuga cgugugccca cuaacccucg ggauagagac cguaggcggc guuaugacaa     1380

aacugauccc ccgcaacacc guaguaccca cgaagaaaag ccaaaucuuc agcacggcaa     1440

gcgacaacca accgaccgua accauaaaag uguaugaggg ggaacgaccc cucacgaaag     1500

acaaccaccu acucggcaca uucgaccuca caggaauacc accagccccg cgcggaguac     1560

cacaaaucga aguaacguuc gaaaucgacg ugaacggaau ccuacgcguc accgccgagg     1620

acaaagggac cggcaacaag aacaaaauca ccaucacgaa cgaccaaaac cgccucacac     1680

cggaggaaau cgaacguaug gucaacgacg cggaaaaguu cgcggaagag gacaagaaac     1740

ucaaagaacg cauagacacg cgaaacgaac uggaaucaua cgcauacuca cugaaaaacc     1800

aaauaggaga caaggaaaag cuaggaggca agcuaucgag cgaggacaaa gaaacaaugg     1860

aaaaggcagu cgaggagaaa auagaauggc uagaauccca ccaagacgca gacauagaag     1920

acuucaaagc gaaaaagaaa gaguuagaag aaaucguuca accaaucauc agcaaacuau     1980

acgguagcgc aggcccaccg ccuacaggcg aggaagauac cgcagaaaaa gacgagcugu     2040

agggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  4783
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt11)

<400>  4783
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagccccac gagagcuagc aguaggaaua gaccucggaa      120

cuacauacuc augcguaggc guauuccaac aaggacgcgu agaaauacuc gcaaacgacc      180

aaggcaaccg caccacgcca agcuacgucg ccuuuaccga caccgagaga cucguaggcg      240

acgcagccaa aucgcaggcc gcccucaauc cccacaacac cgucuucgac gcgaaaagac      300

uaaucggccg aaaauucgcc gauaccacag uccaaagcga caugaaacac uggcccuuuc      360

gcguaguguc agaaggagga aaaccaaaag ucagggucug cuaccgagga gaagacaaaa      420

ccuucuaccc agaagagaua ucgaguaugg uacuauccaa aaugaaggaa accgcagaag      480

ccuaccuagg acaaccagua aagcacgccg ucauaacagu accagcguac uucaacgaca      540

gccaaagaca agccaccaag gacgccgggg ccauagccgg acuaaacguc cuccgcauaa      600

ucaacgaacc gaccgcugcc gcgaucgcau acggccucga ccgcagggga gcuggcgaaa      660

gaaacguccu caucuucgac cucggagggg gaacauucga cgucucagua cuaaguauag      720

acgccggcgu auuugaagua aaagccacag caggcgacac ccaccuagga ggagaagacu      780

ucgacaaccg acucgugaac cacuucaugg aagaguuccg acgcaaacac ggcaaagacc      840

ucuccggcaa caaacgggcc uugagacgac ucagaacagc cugcgaaaga gcaaaaagaa      900

cacucagcuc aagcacacaa gcgacauuag aaauagacuc ccuauucgag ggcguagacu      960

ucuauaccuc gaucacacgc gcaagauucg aggaacugug cucagaccuc uucagaucaa     1020

cccucgaacc ggucgagaaa gcucuaagag acgccaaacu agacaaagca caaauccacg     1080

acgucgucuu aguaggcgga agcacccgaa uaccaaaagu gcaaaaacuc cuacaagacu     1140

ucuucaacgg aaaggagcuc aacaagucaa uaaaccccga cgaagccguc gcauacgggg     1200

ccgcaguaca ggccgcagug cucaugggcg auaaaugcga gaaaguccaa gaccuucuac     1260

uacucgacgu agccccacuu ucccuagggc ucgaaaccgc gggcggggua augaccaccc     1320

ucauccaacg aaacgcaaca auaccaacua aacaaaccca gaccuucaca acauacucag     1380

acaaucaacc gggaguauuc auacaagucu acgaaggcga acgagccaug acaaaagaca     1440

acaaccuucu cggcagguuu gaacucagcg gcauaccccc agccccacgc ggcgucccac     1500

aaauagaagu caccuucgau auagacgcca acggcauacu cagcguaacg gcaaccgacc     1560

gcagcaccgg aaaagcgaac aagauaacca ucacaaacga caaagggcgc cuaagcaaag     1620

aagaggucga gcgcaugguc caugaagcag aacaguauaa agcagaggac gaagcccaac     1680

gagacagagu agcagcgaaa aacagucucg aggcacacgu guuccacguc aaaggcucac     1740

uacaagaaga gagccuacga gacaaaaucc ccgaagaaga caggcggaaa augcaagaua     1800

aaugccgcga aguacucgcu uggcucgagc acaaccaacu ggccgaaaag gaggaauacg     1860

aacaccaaaa acgagaacuc gagcagauau gccgacccau auucucccgc cucuacggcg     1920

gccccggcgu ccccggagga agcagcugcg gcacgcaagc cagacaagga gaccccucaa     1980

ccggacccau aaucgaagaa guggacuaag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  4784
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt11)

<400>  4784
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcccccc gcgaacuagc cguaggcauc gaccucggca      120

caaccuacag cugugucggc guauuccaac aaggcagagu agaaauccua gccaacgacc      180

aaggcaacag aacgacccca ucauacgucg cguucaccga cacagaaagg cuaguaggag      240

acgcagcaaa aucccaagca gcccuaaacc cgcacaacac uguauucgac gccaaacgcc      300

uaaucggacg aaaauucgca gacacaaccg uccaaucaga caugaaacac uggccauucc      360

aagucgucuc cgaaggugga aaacccaaag uacgaguaug cuaccgaggg gaagacaaaa      420

cauucuaccc agaagaaaua agcucaaugg uacuaagcaa aaugaaagaa accgcggaag      480

ccuaccuagg ccaaccagua aaacacgccg uaaucacggu cccgaccuac uucagcaacu      540

cccagagaca ggccaccaaa gacgcaggag caaucgcagg ccuaaaagua cucccaauca      600

uaaacgaagc cacagccgca gcaauagccu acggccugga ccgaagagga gccggcaaac      660

gaaacguacu cauauucgac cuaggaggag gaacauucga cguauccgua cucucgaucg      720

acgccggggu cuucgaagua aaagcuaccg ccggcgacac ccaccuagga ggcgaagacu      780

ucgacaaccg ccuagucaac cacuucaugg aagaauuccg cagaaaacac ggcaaagacc      840

uaagcggaaa caaacgagcc cucagacgac uccgaacagc cugcgaacga gccaaacgca      900

ccccaucaag cagcacccag gccacacuag aaaucgacuc ccuauucgaa ggcguagacu      960

ucuacaaaag caucaccaga gccagauucg aagaacucug cagcgaccua uuccgaagca     1020

cccuagaacc cguggaaaaa gcccuccgcg acgccaaacu agacaaagca caaauccacg     1080

acuucguacu aggcggcggg cuccacagcc acccacaagg cgcagaaguc gccgcaggcc     1140

uacuccaacg acaaggcgca gaacaagaac accagccaua aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  4785
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt11)

<400>  4785
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaaaaggac ccgcaguggg aaucgaccua ggcaccaccu      120

acucaugcgu aggcgucuuc caacacggaa aagucgagau aaucgccaac gaccaaggaa      180

acaggacgac accaucauau guagccuuca ccgacaccga gcgccuaaua ggagacgccg      240

ccaaaaacca ggucgcaaug aacccaacga acaccguauu cgacgccaaa cgacuaaucg      300

gccgccgauu cgacgaugca gucguccaga gcgacaugaa acacuggccc uucaugguag      360

uaaacgacgc cggccgacca aagguacaag ucgaauacaa aggcgaaacc aaauccuucu      420

accccgaaga gguguccagc augguccuca ccaaaaugaa agaaauagca gaagcguacc      480

uggggaaaac agucaccaac gcaguaguca ccguccccgc auacuucaac gacagccaga      540

gacaagcaac aaaagacgca ggcaccaucg ccgggcuaaa cguccuacgc auaaucaacg      600

aacccacagc agcugcaauc gcauacgguc ucgacaagaa aguuggugcc gaacgcaacg      660

uccuaaucuu cgaccucggg ggcggcaccu ucgacguauc aauccucaca auagaagacg      720

gaauauucga agucaaaagc accgcaggcg acacccaccu aggcggcgag gacuucgaca      780

acagaauggu aaaccacuuc aucgcagagu ucaaacggaa acacaagaaa gacaucuccg      840

aaaacaaacg cgcaguacga cgccuacgga cagcaugcga acgcgccaaa cgcacccucu      900

ccuccuccac ccaagcaagc auagaaaucg acagccuaua cgaaggaaua gauuucuaca      960

cauccaucac aagggcgcgc uucgaagaac uaaacgcaga ccucuuccga gguacccucg     1020

acccagucga aaaagcauua agagacgcaa aacuagacaa aagccaaauc cacgacauag     1080

uccugguggg cggaucaacc cguaucccua aaauccaaaa acuacuacag gacuucuuca     1140

acggaaaaga acuaaacaag uccaucaacc cagacgaagc uguggcauac ggcgcggccg     1200

uacaagccgc cauccuaagc ggcgacaaau cggaaaacgu gcaggaccug cuacuccuag     1260

acgucacacc ccucucacua ggcauagaaa ccgcgggcgg cguaaugacc guccuaauaa     1320

aacgaaacac aaccauacca accaaacaaa cgcaaaccuu cacaacauac agcgacaacc     1380

aaccaggggu acucauccaa guauacgaag gcgaacgcgc aaugaccaaa gacaacaacc     1440

uccuaggcaa auucgaacuu acaggaaucc cacccgcacc ccgaggggua ccccaaauag     1500

aaguaacauu ugacauagac gccaacggca uccuaaaugu cagcgccguc gacaaaagca     1560

ccggaaaaga aaacaaaaua acgauaacca acgacaaagg ccgacugagc aaagaagaca     1620

ucgagcgaau gguacaagaa gccgaaaaau acaaagcaga ggaugaaaaa cagcgcgaca     1680

aaguaucaag caaaaacagu cuggaaagcu acgccuucaa caugaaagca acaguggaag     1740

acgaaaaacu ccaaggcaag aucaaugacg aagacaagca gaaaauccuc gacaaaugca     1800

acgaaaucau caacuggcuc gacaagaacc aaacagcaga aaaggaagag uucgaacacc     1860

aacagaaaga acucgaaaaa gucugcaacc ccauaaucac aaaacuguac caauccgcag     1920

gcggaaugcc cggcggcaug cccggaggau ucccaggcgg cggggcacca cccaguggcg     1980

gagccagcuc aggaccgaca aucgaagaag uagacuaagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  4786
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt11)

<400>  4786
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaagcgccu caagagcagc agccgccaga cugguaggag      120

ccgcagcauc aaggggcccg acagcagcca gacaccaaga cucauggaac ggccuaagcc      180

augaagcauu ccgccucgua agccgacgcg acuacgcgag cgaagcaaua aaaggagccg      240

uggucggcau agaccuagga accacgaacu cgugcguggc cguaauggag ggaaaacaag      300

caaaaguacu cgaaaacgcc gaaggggcaa gaacaacgcc cucaguagua gcguucacug      360

cggacggcga aaggcuagua ggcaugccag caaaacgaca agcggugaca aacccaaaca      420

acacguucua cgcaacaaaa cgacucauag gacgacgaua cgacgacccg gaaguacaaa      480

aagacaucaa aaacgucccg uucaaaauag ugcgcgccag uaacggagac gccugggucg      540

aagcccacgg caaacucuac agcccauccc agaucggcgc cuucguccua augaagauga      600

aagagaccgc cgaaaacuac cucggacaca cagcuaaaaa cgcagucauc acugugccag      660

cguauuucaa cgacagccaa aggcaagcca cgaaagacgc cgggcaaaua aguggacuaa      720

acguccuaag ggucaucaac gaaccgacug cagcggcccu ggcauacggc cuagacaaga      780

gcgaagacaa aguaauagcc guauacgacc uaggaggcgg gacauucgac auaagcaucc      840

uagaaauaca gaaaggagua uucgagguaa aaagcacgaa uggggacacg uuccugggug      900

gcgaagacuu cgaccaagca cugcuacgcc acaucgugaa ggaguucaaa cgagaaacag      960

gggucgaccu cacaaaagac aacauggcgc uccaacgagu ccgcgaagca gcggaaaaag     1020

caaaaugcga acuaagcagc agcguacaaa ccgacauaaa ccuacccuac cuaacaaugg     1080

acaguagcgg gccaaaacau cucaacauga aauuaacaag agcucaauuc gaaggcaucg     1140

uaacggaccu aauacgacga accaucgccc cgugccaaaa agccaugcaa gacgcagaag     1200

uaagcaagag cgacauagga gaaguaauac ugguaggcgg caugacaaga augccgaaag     1260

uacaacaaac cguacaagac cuauucggac gagcaccaag caaagccguc aacccggaug     1320

aagcaguggc cauuggcgca gcaauccagg gaggcgugcu agcgggcgau guaacagacg     1380

uacuccuacu agacguaacc ccgcuaagcc uaggaauaga aacccuaggc ggaguauuca     1440

caaagcugau aaacagaaac acaacaaucc caaccaagaa aagccaagua uucagcaccg     1500

cggcagacgg gcaaacccaa guggagauca aagucuguca aggagaacga gagauggccg     1560

gcgauaacaa acugcucggc caauucaccc ugaucggcau accacccgcg ccgagaggag     1620

uaccccaaau cgaggucacg uucgauaucg acgccaacgg cauaguccau guaagcgcca     1680

aagacaaagg aaccggacgc gaacaacaaa uagucaucca aucaagcgga ggccuaagca     1740

aagacgacau cgagaacaug gucaaaaacg cggaaaaaua cgcagaggaa gaccgaagaa     1800

agaaagaaag agucgaagca guaaacaugg ccgaaggaau aauacacgac accgaaacca     1860

aaauggaaga guucaaagac caacuaccag cugacgaaug caacaaacuc aaagaagaaa     1920

uaaguaaaau gcgagagcua cuagcgcgca aagacagcga aacgggagaa aauauacgcc     1980

aggcagcgag cagccugcaa caagcuagcc uaaaacuguu cgaaauggcc uacaagaaaa     2040

uggcauccga aagggaagga agcggaagca gcggcaccgg cgaacagaaa gaagaccaaa     2100

aagaagagaa acaguaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  4787
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt11)

<400>  4787
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagauaaag aagcaggcgg auccgacggg ccacgagaaa      120

ccgccccaac auccgcauac agcucgccag cccgaucacu aggagacacc gguauaacgc      180

cccuuucccc cucccacauc gucaacgaca ccgacucaaa cguauccgaa caacaauccu      240

ucuuaguugu cguggccguc gacuucggaa caacaucauc cggcuaugcc uauucauuca      300

ccaaagaacc ggagugcauc cacgucaugc gucgcuggga aggaggagac cccgggguuu      360

caaaccagaa aacccccacc accauccuuc ucacccccga acggaaauuc cacuccuucg      420

gcuacgccgc ccgggacuuc uaccacgauc uagacccgaa cgaagcaaag caauggcucu      480

accuagaaaa auucaaaaug aaacuucaca ccaccggcga ccucacaaug gauacagacc      540

uuacagccgc aaacggcaag aaagucaaag cgcucgaaau cuucgccuac gcacuccaau      600

acuucaaaga acaagcccuc aaagagcuau ccgaccaagc cggcucagag uucgaaaacu      660

cagacguccg cugggucaua acaguaccug cgauauggaa acaacccgcc aaacaguuua      720

ugagacaagc agccuaccag gcuggacugg cauccccuga aaacucagaa caacucauaa      780

ucgcgcuaga acccgaagcu gcaagcauau acugccgaaa acuccgccuc caccagauga      840

ucgaacugag cuccaaagca gccguaaacg gauacagcgg cuccgacacu gucggcgcag      900

gauucaccca agcuaaagaa cacauccgac gaaaccgcca gucacgcacu uuccuagucg      960

aaaacgucau aggagaaauc uggagcgaac uagaagaagg agacaaauac gucguggucg     1020

auucaggcgg cggcaccguc gaccuaacag uccaccaaau caggcuacca gagggccacc     1080

ucaaagagcu auacaaagca accggcggcc ccuacggauc ccucggugua gacuaugagu     1140

ucgagaaacu gcucuacaaa auauuuggcg aggacuuuau cgagcaauuc aaaaucaaac     1200

gccccgccgc cugggucgac uugaugaucg ccuucgaaag ccgaaaacgc gccgccgccc     1260

ccgacagaac aaacccacua aacaucaccu uacccuucuc guucaucgac uacuacaaga     1320

aauuucgcgg ccacuccguc gagcacgccc uacgaaaaag caacgucgac uucgucaaau     1380

ggucaucgca aggaaugcuc cguauguccc ccgacgccau gaaugcccua uucaaaccca     1440

caauagacuc caucaucgaa caccuccgcg accucuuuca aaagccagaa guaucaaccg     1500

ucaaauuucu cuuccuaguc ggcggcuucg cagaagcacc ccuacuccaa caagccguuc     1560

aagccgcuuu cggcgaccaa ugcagaauca uaaucccaca agacguagga cucaccauuc     1620

ucaaaggcgc cguacuuuuc ggccucgacc cagccgucau uaaagugcga agauccccuc     1680

ugacauacgg cgucggaguc cuaaaccgcu acgucgaagg aaaacaccca cccgaaaaac     1740

uucuagucaa agacggcacc cgauggugca ccgacguauu cgauaaauuc auaucagcag     1800

accaaagcgu cgcccucggc gagcuaguca aaagauccua cacacccgcc aaaccaagcc     1860

aacucgucau cguuaucaac auauacucca gcgaacacga caacguaucg uucauaaccg     1920

accccggggu aaagaaaugc ggcacccucc gccucgaccu aacaggcacc ucaggcaccg     1980

ccgucccagc acgcagagaa auacaaaccc ucaugcaguu cggugacacc gaaaucaaag     2040

ccaccgccau cgacauagca accaguaaau cggucaaagu aggcauagac uuucuaaacu     2100

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  4788
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt11)

<400>  4788
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuagccgucc cagaaauggg cuuacaagga cuuuacaucg      120

gaagcucccc agaacgauca cccguaccca gcccacccgg aucaccccgc acccaggaau      180

caugcggaau cgcgccccug acacccagcc aaagcccaaa acccgaagua cgggccccgc      240

aacaagccuc cuucagcgua gucguggcca uagacuucgg aacgaccagc aguggcuacg      300

cauucucauu cgcaagcgau ccagaggcca uacacaugau gcgaaaaugg gaaggcggcg      360

acccaggagu agcacaccag aaaaccccaa caugccuacu ccuaaccccc gaaggcgccu      420

uccacucauu cggcuacacu gcaagagauu acuaccacga ccucgacccg gaagaagccc      480

gcgacuggcu cuacuucgag aaauucaaga ugaaaaucca cagcgccaca gaccuaacac      540

ugaaaaccca acucgaggcg gugaacggca agacaaugcc agcacucgaa guauucgcac      600

acgcccuccg auucuuccgc gaacacgcac uacaagaacu acgcgaacaa agccccaguc      660

ugcccgagaa ggacaccguc cggugggugu uaaccguacc cgcaaucugg aaacaaccag      720

caaaacaauu caugcgcgaa gccgccuacu uagccggacu uguaagcaga gagaacgcag      780

aacaacuccu cauagcccug gaacccgaag ccgccuccgu auacugccga aaacuacgac      840

uacaccaacu acuagaccug ucgggccgcg cccccggcgg cggccgccua ggcgaaagac      900

gaagcauaga cuccuccuuc cgccaagccc gagaacaacu aagaagaucc agacacucac      960

gaaccuuccu aguagaaucc ggagucggag aacuaugggc cgaaaugcaa gccggcgacc     1020

gcuacguagu cgccgacugc ggagggggca cugucgaccu uaccguacac caacuagaac     1080

aaccacaugg cacccuaaaa gaacuauaca aagccucggg aggucccuac ggggcugucg     1140

gcguagaccu cgcauucgag caacuccuau gccgcaucuu cggagaagac uucaucgcaa     1200

cauucaaacg ccaaaggccc gccgcauggg ucgaccucac uaucgccuuc gaagcacgaa     1260

aacgaacagc aggaccccau cgcgcaggcg cccucaacau cucacuaccc uuuuccuuca     1320

uagacuuuua cagaaaacaa agagggcaca acguagagac agcacucaga cgauccagcg     1380

ugaacuucgu aaaaugguca ucccaaggga ugcugcgaau gucaugcgaa gcaaugaacg     1440

agcuauucca accaacagua ucaggcauaa uccaacacau cgaagcacug cucgcccgac     1500

cagaaguaca aggcguaaag cuccucuucc uagucggcgg auucgccgaa agcgcagucc     1560

uccaacaugc cguccaagcc gcccugggcg cacgcggacu acgagucguc guaccacacg     1620

acgucggacu cacgauacuc aaaggagccg uacuauucgg acaagcccca ggaguagucc     1680

gcguccgccg uucgccgcuc accuacggcg ucggcguccu caacagauuc guaccaggac     1740

gccauccccc agaaaaacug cugguccgcg acggccgcag augguguaca gacgucuucg     1800

aacgcuucgu agcagccgag caauccgucg cgcuaggaga ggaaguccgc cguucauacu     1860

gucccgccag acccggccaa cgaagaguac ucaucaaccu auacugcugc gcagcagaag     1920

acgcacgcuu cauaacugac ccaggcgucc ggaaaugcgg cgcccucuca cuagaacucg     1980

aacccgccga cugcggacag gacaccgcag gagccccacc cggacgacgc gaaauucggg     2040

ccgccaugca auucggcgac accgaaauca aggugacagc cguggacguc agcacgaacc     2100

gcagcguuag agcaagcaua gacuuccucu caaacuaagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  4789
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt11)

<400>  4789
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgcgaaa ugaccauccu cggcucagcc guccuuaccc      120

uacuacuagc gggauaccua gcccaacaau accuuccacu acccaccccc aaagucauag      180

guauagaccu cggaaccacc uacugcuccg ucggcgucuu cuuucccgga accggaaaag      240

ucaaagucau cccagacgaa aacggacaca ucucuauccc cucgaugguc agcuucacag      300

acaacgacgu auacgucggc uacgaauccg ucgagcuagc cgacagcaac ccacaaaaca      360

caaucuacga cgccaaacgc uucaucggca aaaucuucac cgccgaagaa cucgaagccg      420

aaaucggacg cuaccccuuc aaaguacuca acaaaaacgg cauggucgag uucucaguaa      480

ccagcaacga aaccauaacc guaucccccg aauacgucgg cucacgcuua cuacuaaaac      540

ucaaagagau ggcagaggcu uaccucggca ugccggucgc caacgcuguc auaagcgucc      600

ccgcggaguu cgaccucaaa caacgcaacu ccaccauuga agcagcgaac cuggcaggac      660

uaaaaauccu ccggguaaua aacgaaccca cagcagcagc cauggccuac ggacuccaua      720

aagccgacgu cuuucacguu cuagucaucg acuuaggcgg aggcacccuc gacgucuccc      780

uccucaacaa acagggcgga auguuccuaa cacgcgccau gucaggcaac aacaaacucg      840

gcggccagga cuucaaccaa cgccuacuuc aauaccucua caaacagauc uaccagaccu      900

auggauucgu acccucucgg aaagaagaaa uccaccgccu ccgccaagcc guagaaaugg      960

uuaaacucaa ccucacccua caccagucag cgcaacuauc cguccuccuc acggucgaag     1020

aacaagaccg caaagaaccc cacucaucag acaccgaacu ccccaaagac aaacucuccu     1080

cagccgacga ccaccgcgug aacucaggcu ucggccgcgg ccuauccgac aagaaauccg     1140

gcgaaucuca aguacucuuc gagacagaaa uaagccgcaa acucuucgac acccuaaacg     1200

aagaccucuu ccagaaaaua cucguaccca uccaacaagu ccuaaaagaa ggccaccuug     1260

agaaaaccga aaucgacgaa gucguucucg ucggcggcuc cacccgcauc ccccguauuc     1320

gacaagucau acaagaauuu uucggaaaag aucccaacac uagcgucgac cccgaccuug     1380

caguagucac agggguagcc auccaagccg gaauagacgg cggauccugg ccccuucaag     1440

ucuccgcacu cgaaaucccc aacaaacacc uucagaaaac caacuucaac uagggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4790
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt11)

<400>  4790
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgccaucg gaguccaccu cggcugcaca uccgccugcg      120

uggccgucua caaagacgga cgcgcaggcg uagucgccaa cgacgccgga gaccgcguca      180

cccccgccgu agucgccuac agcgaaaacg aggaaauagu cggacucgcc gccaaacaau      240

cccgaauacg caacauaucc aacacaguaa ugaaagucaa acaaauccuc ggacgaagca      300

gcagcgaccc acaagcccaa aaauacaucg ccgaauccaa augccuuguc aucgagaaaa      360

acggaaaacu acgauacgaa aucgacacag gggaagaaac caaguucguc aacccagagg      420

acgucgcacg ccucaucuuc agcaaaauga aggagaccgc acauagcgua cuaggguccg      480

acgccaacga cgucguaaua accgucccau uugacuucgg cgaaaaacaa aagaacgcac      540

uaggcgaagc cgcccgcgcc gcuggcuuca acguccugcg acuaauacac gaaccaucag      600

cagcacuacu agccuacggc aucggacaag acucaccaac aggcaaauca aacauacucg      660

uauucaaacu cggaggcacu agccuaucac uauccguaau ggaggugaac agcggcaucu      720

accgcguacu caguaccaac acagaugaca acauaggcgg cgcccacuuc acagaaaccc      780

uagcgcaaua ccuagcgucg gaauuucaac gcagcuucaa acacgacguc agaggaaacg      840

cccgcgcgau gaugaaacua accaacagcg cggaagucgc aaaacacucc cucucaaccc      900

ucggcuccgc caacugcuuc cucgacucac ucuacgaagg ccaggacuuc gacugcaacg      960

ucucaagagc ccgcuucgaa cuccugugcu ccccacuauu uaacaaaugu aucgaagcaa     1020

uacgcggacu ccuagaccaa aacggcuuca cagccgacga caucaacaaa gucguccucu     1080

gcggcggcag cucgcgcauc cccaaacucc aacaacuaau caaagaccuc uucccagccg     1140

ucgaacuacu caacucgauc ccacccgaug aaguuauucc cauuggagcc gccaucgaag     1200

ccggcauccu aaucggcaaa gaaaaccuac ugguagaaga cucacuaaug aucgaaugcu     1260

cagcccgcga cauccucguc aaaggagucg acgaaagcgg agccucccga uucaccguac     1320

uauucccuuc cggaacgccg cucccagccc gccgacaaca cacccuccaa gcccccggcu     1380

ccaucuccuc cgucugccuc gaacucuacg aaagugaugg caaaaacuca gccaaagaag     1440

aaaccaaauu cgcgcaagua guacuacaag accucgacaa gaaagaaaac ggacuacgcg     1500

acauccuagc cguacucacc augaaacgcg acggaucacu ccacguaacc ugcacagacc     1560

aagaaacagg caaaugcgaa gcuaucucca uagaaaucgc cucaugagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  4791
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt11)

<400>  4791
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgugguag gacucgacgu cgggagccaa agcugcuaca      120

uagcgguagc cagggcaggc gggauagaga cgaucgccaa cgaguucucc gaucgcugca      180

cacccagcgu caucagcuuu gguucuaaaa acaggacuau aggaguggcc gccaaaaacc      240

aacaaauaac ccaugcaaac aacaccguca gcaacuucaa acgauuccac ggacgugccu      300

ucaacgaccc cuuuauacaa aaagaaaaag aaaaccuauc cuacgaccua gucccccuca      360

agaauggagg cgugggcauc aaaguuaugu auaugggaga agaacaccug uucucaguag      420

aacagauaac cgccaugcua cuaacaaaac ugaaggaaac cgcagagaac agucugaaga      480

aaccugucac cgacugcgua aucuccguac ccuccuucuu caccgacgca gaacggagau      540

ccguacuaga cgcagcccaa auaguaggcc uaaacugccu ccgccugaug aacgauauga      600

cggccguagc acucaacuau gggauuuaca aacaagaccu cccaagccuc gacgaaaaac      660

cccgcauagu agucuucguc gacaugggac acucagcauu ccagguaagc gcaugcgccu      720

ucaacaaagg aaaacucaaa guccuaggca cggcuuucga ccccuuccua ggcgggaaaa      780

auuucgacga gaaacucguc gaacacuucu gcgccgaguu caaaaccaaa uacaaacucg      840

acgcaaagag caaaauccga gcccuccuac gccuauacca ggaaugcgaa aagcuaaaga      900

aacugauguc cuccaacucc accgaccuac cccuaaacau cgaauguuuc augaacgaca      960

aggacgucag cggaaagaug aacagauccc aguucgagga gcucugcgcc gagcuacucc     1020

aaaagauaga agucccccuc uacagccuuc ucgaacagac ccaccucaaa guagaagacg     1080

uuucagccgu cgaaaucguc ggcggagcaa cacgcauccc cgcggucaaa gaacgcaucg     1140

ccaaauucuu cgggaaggac auauccacca cccuaaacgc agacgaagca guggcacgcg     1200

ggugugcccu ccagugcgcc auccuaagcc ccgcauucaa aguacgagag uucucaguaa     1260

ccgaugccgu cccguuccca auaagccuga uauggaacca cgacagcgag gacaccgaag     1320

guguccacga agucuucagu cgaaaccacg cggccccauu cucaaaagua uuaacguucc     1380

uccgacgcgg acccuucgaa cucgaagcau ucuacagcga cccgcaaggc guaccguacc     1440

cugaggcaaa gauuggcagg uucguagucc agaacgucuc cgcacagaaa gauggcgaga     1500

aaagccgcgu aaaggucaaa guccgaguca acacacacgg aaucuucacc auuuccaccg     1560

ccucaauggu agaaaaaguc cccacagaag aaaacgagau gagcucugaa gccgacaugg     1620

agugccucaa ccaacgccca cccgaaaacc ccgacaccga caagaacguc caacaagaca     1680

acagcgaagc aggaacccag ccccaagucc aaaccgacgc acaacagacc agccagagcc     1740

cacccucccc cgagcucaca ucagaagaaa auaagauccc agacgcagac aaggccaacg     1800

aaaagaaagu cgaccagccc ccggaggcca agaaacccaa aaucaaagug gucaacguag     1860

aacuccccau cgaagcaaac cuggucuggc agcuagguaa agacuuacua aacauguaca     1920

ucgaaaccga aggcaaaaug auaaugcaag auaaacucga aaaagaacgc aacgacgcca     1980

aaaacgcagu cgaagaauac guauacgagu uccgggacaa acuaugcggc ccauacgaaa     2040

aauucaucug ugaacaagac caccaaaacu uucuacgucu auuaaccgaa accgaagacu     2100

ggcucuacga agaaggcgaa gaccaagcaa aacaggcuua cgucgauaaa cuggaagaac     2160

uaaugaaaau cggaacgccg gucaaagugc gguuccaaga agcagaagaa cgucccaaaa     2220

uguucgagga acucggacaa agacuccaac acuacgcgaa aaucgccgcc gacuuccgca     2280

acaaagacga gaaguacaac cacaucgacg aaucagaaau gaagaaagua gaaaagucgg     2340

ucaacgaagu aauggaaugg augaacaacg uaaugaacgc ccaagccaaa aagucccucg     2400

accaagaccc agucguccga gcacaagaaa ucaaaaccaa aauuaaggaa cugaacaaua     2460

ccugcgagcc cgucguaacg caaccgaaac caaaaauaga aucccccaaa cucgaacgaa     2520

cccccaacgg gccgaacauc gacaagaaag aagaagaccu cgaggacaaa aacaacuucg     2580

gagcagaacc accacaccaa aacggcgaau gcuacccaaa cgagaaaaac agcgucaaca     2640

uggaccucga uuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  4792
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt11)

<400>  4792
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagacaagg ucaggcggca acgaccacgg aggcgcguau      120

guugggcgcu agucgcaguc cuacuugcgg accuacuggc acuaagcgac acgcuggcag      180

uuauguccgu agaccucgga agcgaaucga ugaaagucgc gaucgucaaa cccggcgucc      240

caauggaaau aguccuaaac aaggaaagcc gcaggaagac cccggugaua gugacacuca      300

aagagaacga acgcuucuuc ggagacucgg ccgcgagcau ggccauaaag aaccccaaag      360

caacgcuaag auacuuccaa caccuccucg ggaaacaagc agacaaccca cacguggcac      420

ucuaccaggc aagguuccca gaacacgagc ugacauucga cccgcaacgc caaacgguac      480

acuuccaaau aucaucacaa cugcaauuuu cacccgaaga aguccuagga auggugcuca      540

acuacuccag aucauuagcc gaagauuucg ccgaacaacc aauaaaagac gcagucauaa      600

caguacccgu cuucuucaac caggcagaac gccgagcagu ccuacaagcc gcgaggaugg      660

caggccuuaa aguccuccaa cugaucaacg acaacaccgc aacagcacug agcuauggcg      720

ucuucagacg gaaggacaua aacaccaccg cacagaauau aauguuuuac gacaugggaa      780

gcggauccac agugugcacc auaguaaccu accaaauggu gaaaacgaag gaggccggca      840

ugcaaccuca gcuccaaauc cgagggguag gauucgaccg gacacucggc gggcuagaaa      900

uggaacuacg gcuaagagaa agauuagcgg gacuguucaa cgaacagcga aaaggacaac      960

gagcgaaaga cgucagggaa aacccccgcg cgauggcaaa gcuccuucga gaggcaaacc     1020

gccugaaaac agugcuguca gcgaacgcgg accacauggc ucaaauagaa ggacucaugg     1080

acgacgucga cuucaaagca aagguaacac gagucgaauu ugaagaacua ugcgcggauc     1140

uauucgaaag agugcccgga cccguacagc aagcacugca guccgccgaa augucccuag     1200

augaaauaga acaaguuauc cuagucggcg gcgccaccag aguaccacga gugcaggaag     1260

uacuacucaa agccguaggc aaggaggaac uagggaaaaa cauaaacgcc gacgaagcag     1320

cagcgauggg ggcaguuuac caagccgccg cacucagcaa ggcauucaaa gucaaacccu     1380

ucgucguacg agacgccguc guauacccga uacugguaga guucacacgc gaaguggagg     1440

aggaaccagg aauacauagc cugaaacaca acaagcgagu ucucuucagc cgaaugggcc     1500

ccuaccccca aagaaaagug aucaccuuca accgguacag ccacgacuuc aacuuccaca     1560

uaaacuacgg cgaccucgga uucuuggggc ccgaagaccu caggguauuc gggagccaaa     1620

accugacaac agucaaacuc aaaggcguag gcgacagcuu caaaaaguac ccagauuacg     1680

aaaguaaagg cauaaaagca cacuucaauc uugacgaaag cggagugcuc ucgcucgacc     1740

gcguggagag cgucuuugaa acccuaguag aggacagcgc cgaagaagaa agcacgcuaa     1800

caaagcuggg aaacaccaua uccucacuau ucggaggggg aacgacacca gacgcaaaag     1860

agaacggaac cgacaccguc caagaagagg aagagagccc agcugaaggg uccaaagacg     1920

agccaggaga acaaguugaa cuuaaagaag aagcggaggc cccuguugag gacggaagcc     1980

aaccgccccc acccgaaccc aaaggcgacg ccacaccaga aggcgaaaag gcaaccgaga     2040

aggaaaacgg agacaaaucc gaagcccaaa aaccaagcga aaaagcagag gccggcccag     2100

aaggggucgc gcccgcaccg gaaggggaga agaagcaaaa acccgcacga aaacgcagaa     2160

ugguggaaga aaucggagua gagcuagucg uacuagaccu accagaucug ccggaagaca     2220

aacuagcaca aucaguucag aaacuucaag acuugacccu acgggaccug gaaaaacaag     2280

aaagagaaaa agcagccaac agucucgaag ccuucaucuu cgagacacaa gacaaacugu     2340

accaacccga guaccaggaa guaagcacag aagaacagag agaagaaauc aguggaaaac     2400

ugagcgcugc gucaacaugg cuagaagacg aagggguagg ugcaacaacc gucaugcuua     2460

aagaaaagcu cgccgaacug cgcaaacucu gccaagggcu auucuuccga guagaagaga     2520

ggaagaaaug gccagaaagg cuauccgcac uagacaaccu acugaaccac ucgagcaugu     2580

uccuaaaggg agcaagacuc auaccagaga uggaccaaau auucaccgag guggaaauga     2640

caacacucga aaagguaaua aacgaaacgu gggccuggaa aaacgccaca cuagcagagc     2700

aagccaaacu gccagcaaca gagaaaccag uacugcuauc aaaggacauc gaagcaaaaa     2760

ugauggcacu ggacagagag gugcaauacc uccucaacaa agcaaaauuc acaaaaccca     2820

gaccacgacc aaaagauaag aacggaacac gcgcagagcc accccuaaau gcuucggcga     2880

gcgaucaagg ggagaaagua auacccccag ccgggcaaac cgaggacgcc gagccgaucu     2940

ccgaacccga aaaggucgaa acaggcucag aacccgggga uacagaacca cuugaacucg     3000

gcggacccgg agccgagcca gaacagaagg aacaaaguac agggcaaaaa cgcccccuga     3060

aaaacgacga acuauaggga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4793
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt11)

<400>  4793
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaagaaa cccaaacaca agaucaacca auggaagaag      120

aagaagugga aaccuucgcg uuccaggcgg aaauagccca acuaaugucc cucaucauca      180

acaccuucua cagcaacaag gaaaucuucc ugcgagaacu uaucagcaac agcagcgacg      240

cccucgauaa gaucagauac gaaagccuaa cugacccaag caaacuagau agcgggaaag      300

aacuccacau caaccuaaua cccaacaaac aagaccggac ccucacaaua guagacaccg      360

gaaucggaau gacaaaggcg gaccuuauaa acaaucuggg aaccaucgcg aaaagcggga      420

caaaggcauu cauggaagcg cuccaggcag gggcagacau aucaaugauc ggccaauucg      480

gagucggcuu cuacucagcg uaccuaguag ccgagaaagu aaccgucaua accaaacaca      540

acgacgauga gcaguacgcg ugggagagca gcgcgggagg aucguucaca gugagaaccg      600

acacagggga accgauggga cgcggaacga aaguaauacu acaccucaaa gaagaccaga      660

ccgaauaccu cgaagaaagg cgaauaaaag aaauagugaa gaaacacucc caguucaucg      720

gauacccgau aacacuauuc guggagaaag agcgcgacaa agaggucagc gacgacgaag      780

cagaagaaaa agaagacaaa gaagaggaaa aggaaaaaga agaaaaagaa agcgaagaca      840

aaccagagau cgaagacgug ggaagcgacg aagaagaaga aaagaaagau ggagacaaga      900

agaaaaagaa gaaaaucaaa gagaaauaca uagaccaaga agaacuaaac aaaacgaaac      960

caaucuggac ccggaaccca gacgacauaa ccaaugaaga auacggcgag uucuacaaau     1020

cacucacaaa cgacugggaa gaccaccucg ccguaaaaca cuucucggua gagggacaac     1080

uagaguuccg agcgcuccug uucgugccaa ggcgagcccc auuugaccug uucgagaaua     1140

gaaagaagaa aaacaacaua aaacucuacg uccgccgggu cuucaucaug gacaacugug     1200

aagaacuaau uccggaauac cugaacuuca uccgcggcgu aguggacagc gaagaccugc     1260

cgcucaacau cucgagagaa auguuacaac aaagcaaaau ccucaaagua auaaggaaga     1320

accucgugaa gaaaugccug gaauuauuca cagaacuagc cgaagacaaa gaaaacuaca     1380

agaaauucua cgagcaauuc agcaaaaaca uaaaacuggg cauccacgaa gacagccaaa     1440

accgcaagaa acuauccgag cuccuacgcu acuacaccuc cgcauccggg gaugagaugg     1500

ugucacuaaa agacuacugc accagaauga aagaaaacca aaaacacauc uacuacauca     1560

cgggcgaaac aaaagaccaa guagcgaacu cagccuucgu cgagcgccua cgaaaacacg     1620

ggcuagaagu cauauacaug aucgaaccaa uagacgaaua cugcguccaa caacucaaag     1680

aguucgaagg aaaaacccuc gucagcguua ccaaagaagg cuuggagcuc cccgaagacg     1740

aagaagagaa aaagaaacaa gaagaaaaga aaaccaaauu cgaaaaccug ugcaaaauca     1800

ugaaggacau acuggaaaag aaaguagaga aggucguagu aucaaacagg cucgugacca     1860

gccccugcug cauagucaca ucuaccuacg gauggacggc caacauggaa agaauaauga     1920

aggcccaagc acuccgcgac aacucgacaa ugggcuacau ggcggccaag aaacaccucg     1980

agaucaaccc cgaccacucc aucaucgaaa cgcucaggca gaaagccgaa gcagacaaaa     2040

acgauaaauc cgugaaggac cucguaauac uccuauauga aacggcccuu cuaagcagcg     2100

gguucagccu cgaagacccg caaacgcacg cgaacaggau cuaccgaaug aucaaacucg     2160

gccuugggau cgacgaagac gacccaacag cagacgacac gagcgcggcc guaacggaag     2220

aaaugccacc acuagaaggc gacgacgaca cgagcaggau ggaggaagug gacuagggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  4794
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt11)

<400>  4794
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucaa aacuggacuc gggcaagggc cugcacauaa      120

accugguccc gaacaagcaa aaccaaacac ucacgaucgu ggacacgcgc auaggcauga      180

ccaagaccga ccucauaaac aaccucggga ccgugaccaa gagcgggacc aaggccuuca      240

uggaggcccu gcaagcggac gcggacauaa gcaugaucgg acacuucggc gugggcuucu      300

acucggccua ccucguggcc aagaaaguga ccgugaucuc aaaacacaac aacgacgagc      360

aauacaccug ggaaucgagc gcgggcggga gcuucaccgu gcgcacggac gaguaaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  4795
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt11)

<400>  4795
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaagaag ugcaccacgg ggaagaggaa gucgaaaccu      120

ucgccuucca ggccgagaua gcccaacuca ugagcuuaau cauaaacacc uucuacucca      180

acaaagaaau cuuccucaga gaguugauau caaacgcaag cgacgcccug gacaagauaa      240

gauacgaaag ccuaacagac ccaucaaaac uggacucagg aaaggaguua aaaauagaca      300

ucaucccaaa cccacaagaa cgcacgcuca cccucgugga caccggaaua ggaaugacaa      360

aagccgaccu cauaaacaau cucggcacga uagccaagag cgggacaaaa gccuucaugg      420

aggcccuaca agcaggagcc gacauaagca ugaucggaca auucggcgua ggcuucuaca      480

gcgcauaccu cgucgccgaa aaggugguag uaaucacaaa acacaacgac gacgaacaau      540

acgccuggga aagcagcgcc ggcgggagcu ucacagucag agcagaccac ggcgaaccua      600

uaggacgcgg gacuaaagua auccuccacc uaaaggaaga ccaaaccgaa uacuuagaag      660

agcgcagggu caaggaaguc gucaaaaaac acagccaguu caucggcuac cccauaaccc      720

ucuaccugga aaaagagagg gaaaaggaaa uaagugacga cgaggccgag gaagaaaaag      780

gagaaaaaga agaagaagac aaagacgacg aagaaaagcc caagaucgaa gacguaggaa      840

gcgacgaaga agacgacuca ggaaaggaca agaaaaaaaa aacgaaaaaa aucaaagaga      900

aauacaucga ccaagaagag cugaacaaaa caaaaccaau cuggaccagg aaccccgaug      960

acaucacaca agaagaauac ggggaauucu acaaaucgcu aacaaacgac ugggaggacc     1020

accucgcggu aaagcacuuc agcguggaag gacaacucga auucagagca cuacuauuca     1080

ucccaaggag agcgccauuc gaccuguucg aaaacaagaa aaaaaaaaac aacauaaagc     1140

uauacguccg acgagucuuc auaauggacu caugcgacga acugauccca gaauaccuaa     1200

acuucauccg gggcguagua gacuccgaag accucccacu caacaucagc cgagaaaugc     1260

uacaacagag caagauacug aaagugauca gaaaaaacau cguaaaaaag ugccuagaac     1320

uauucagcga auuagcagag gauaaagaaa acuacaagaa auucuacgaa gccuucagca     1380

agaaccuaaa acugggcaua cacgaagaca gcaccaaucg aaggcgccua agcgaacuac     1440

uaagauacca cacaagucag agcggcgacg agaugacgag ccuauccgaa uacguuagcc     1500

ggaugaaaga aacgcaaaag ucaauauacu acaucaccgg agagagcaag gaacaaguag     1560

cgaacucggc auucgucgaa cgcgugcgaa agcgcggauu cgaagucgua uacaugacgg     1620

agcccaucga cgaguacugu guacaacagc ucaaagaauu cgacggcaaa agccuagucu     1680

caguaaccaa agaaggacua gaauugcccg aagacgaaga agagaagaaa aaaauggaag     1740

aaucaaaagc caaauucgag aacuugugca agcugaugaa agagauccua gacaaaaagg     1800

uagaaaaggu cacgaucuca aaccggcugg ugagcucgcc cugcugcauc gucacgagca     1860

cauacggcug gacagcaaac auggaacgaa uaaugaaagc acaagcccuc agagacaacu     1920

caaccauggg guacaugaug gccaagaaac accucgaaau aaaccccgac cacccuauag     1980

uagaaacgcu caggcaaaag gccgaagcag acaaaaacga caaagccgua aaagaccucg     2040

ugguccugcu cuucgaaaca gcccuacucu caagcggauu uucacuggag gacccacaaa     2100

cccacagcaa cagaaucuac cgaaugauua agcucggacu ggguauugac gaggacgaag     2160

uagccgcgga agagcccaac gcggcagucc ccgacgaaau cccgccccug gaaggggacg     2220

aggacgcauc aagaauggaa gaggucgacu agggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  4796
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt11)

<400>  4796
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agagcccuau gggugcucgg gcucugcugc guacuacuca      120

cguucggauc aguccgagca gacgacgagg ucgacgucga cggaacgguc gaagaagacc      180

uaggaaaaag ccgcgaaggc agccggacag acgacgaggu cguccagcga gaggaagagg      240

caauacaacu cgacggucua aacgccagcc agauacgcga gcuccgggag aaaagugaaa      300

aauucgccuu ccaagcagag gucaacagaa ugaugaaacu cauaauuaac ucccuauaca      360

aaaacaaaga aauauuccug cgggaacuaa ucuccaacgc cagcgacgcc uuagacaaaa      420

uacgacucau cagccugaca gacgaaaacg ccuugagcgg gaacgaggaa cuaaccguga      480

aaauaaaaug cgacaaagag aagaaccugc uacacguaac ggauacggga guaggcauga      540

cacgagaaga acucgucaaa aaccucggaa ccauagccaa gagcggcaca agcgaguucc      600

ucaacaaaau gacagaagcc caggaggacg gccaaucaac gagugagcuu auaggccaau      660

ucgggguagg guucuacagc gcguuccuag uagcggacaa aguaauaguc acaagcaaac      720

acaauaacga uacacagcac auaugggaau cagacagcaa cgaauuuagc gugaucgcgg      780

acccgcgggg aaacacgcuu ggcagaggaa ccaccaucac ucuaguacuc aaggaagagg      840

cuucagacua ucuagaacug gacacaauca aaaaccucgu aaagaaauac agccaauuca      900

uaaacuuccc gauauacguc uggagcucga aaacagaaac aguagaggag ccgauggagg      960

aggaagaggc agccaaagaa gaaaaagaag aaucggacga cgaagcggca gucgaagaag     1020

aagaggaaga gaaaaagccc aaaaccaaga aaguagagaa aaccguaugg gacugggaac     1080

ucaugaacga cauaaaaccc auauggcagc gcccgagcaa agaagucgag gaagacgaau     1140

acaaagccuu cuacaagagc uucagcaaag aaagcgacga cccgauggcc uauauacacu     1200

ucacagccga aggagaggug acguucaaaa gcauccucuu cgucccgacg agcgccccca     1260

ggggacucuu cgacgaauac gggaguaaga aaagcgacua caucaaacua uacguccgac     1320

ggguguucau aaccgacgac uuccacgaca ugaugcccaa guaccugaac uucgucaaag     1380

gagugguaga uucagaugac cugccacuca acguaagcag agagacgcuc caacagcaca     1440

aacugcucaa gguaauacgc aagaagcuag ucaggaaaac gcucgacaug aucaaaaaga     1500

uugcggacga uaaguacaac gacacguucu ggaaggaguu cggaacgaac auaaaacuag     1560

gcguaaucga agaccacagc aaccgaacaa gacucgcaaa acuccucaga uuccagagca     1620

gccaucaccc cacagacaua acaagccugg accaauaugu ggaacgaaug aaagaaaaac     1680

aggacaaaau cuacuucaug gcgggaucca gccgcaaaga ggcagaaagc agccccuucg     1740

uagaacgacu ccuaaagaaa ggcuacgaag ucaucuacuu gaccgaacca guagacgaau     1800

acugcaucca ggcccuuccc gaguucgacg gcaagagauu ccaaaacguc gcgaaggaag     1860

gcguaaaauu cgacgaaagc gagaagacga aagaaucgag ggaagcaguc gagaaagagu     1920

ucgaaccacu gcucaacugg augaaagaca aagcgcuaaa agacaagaua gaaaaagcgg     1980

uaguaucgca acggcugacc gaaagcccau gcgcccuagu cgcgagccaa uacggcugga     2040

gcgggaacau ggaaagaauu augaaagcgc aagccuacca gacaggaaag gacaucagca     2100

ccaacuacua cgccagccaa aagaagacgu ucgaaaucaa cccaagacac ccgcuaauaa     2160

gagacaugcu acgaaggauc aaggaagacg aggacgacaa gaccgugcuc gaccucgcgg     2220

ucgugcuauu cgaaacggcc acgcuuagaa gcggauaccu gcuacccgac acgaaagccu     2280

acggcgaccg aaucgaacgc augcuaaggc ucagucuaaa cauagacccc gacgcgaaag     2340

uggaagagga accagaggag gaaccagaag aaacggcaga ggacaccacc gaggacacag     2400

aacaggacga ggacgaggag auggacgucg gaacggacga agaggaagaa accgcaaagg     2460

aaucgaccgc agaaaaggac gagcuauaag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  4797
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt11)

<400>  4797
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgcgaau uacgagcccu acuacuaugg ggucgccgac      120

uccgcccacu acuccgagcc cccgcacucg ccgcaguccc uggaggaaaa cccauacucu      180

gcccccgaag aacaacagcu caacucggcc cccgucgcaa cccagccugg ucgcuccagg      240

ccggccgacu cuucuccaca caaaccgccg aagacaaaga agaaccccuc cacagcauaa      300

ucagcagcac cgaguccgua caaggaagca ccuccaaaca cgaguuccag gccgaaacca      360

agaaacuucu cgacaucgua gcccgaaguc uauacuccga aaaagaaguc uucauccgag      420

aacuuaucuc uaacgcaucc gacgcacucg aaaaacuacg acacaaacuc guaucagacg      480

gucaagcacu acccgaaaug gaaauacauc uacaaaccaa cgcagaaaaa gguaccauaa      540

caauucaaga cacgggaaua ggaaugacgc aggaggaacu cgucucaaac cuaggcacua      600

uagcccgaag cggcagcaaa gccuuccucg acgcccucca aaaccaagcc gaagccuccu      660

ccaaaaucau cggucaguuc ggcguaggcu ucuauuccgc cuucauggua gcagaccgag      720

ucgaaguaua uucucgcuca gcagcccccg gcucccuagg cuaccaaugg cuauccgacg      780

gcagcggcgu guucgaaaua gcagaagccu cgggcguccg uacaggcacc aaaaucauca      840

uacaccuaaa aagcgacugc aaagaauuua gcucagaagc ccgcguccga gacgucguca      900

ccaaauauuc aaauuucguc ucauuuccac ucuaucuaaa cggcagacgc augaacacgc      960

uccaagccau cuggaugaug gacccaaaag acguccgcga auggcagcau gaagaguucu     1020

accgcuacgu agcacaagcg cacgacaaac cacgcuacac ccuccacuac aaaacggacg     1080

ccccacuaaa cauccgcucc aucuucuacg uaccggacau gaaacccagc auguucgacg     1140

uaucccgcga acucggcuca ucgguagcac ucuacucuag gaaaguccuc auacaaacaa     1200

aagccaccga cauccuacca aaauggcuuc gauucaucag aggcgucguc gacagugaag     1260

acaucccccu caaccucuca cgagaacucc uacaagaauc cgccuuaauc cgaaaacucc     1320

gcgacguacu ucaacagcgu cucauaaaau ucuucaucga ucaauccaag aaagaugcag     1380

aaaaauacgc caaauucuuc gaagacuacg gccucuucau gcgggaaggc aucguaacag     1440

caaccgagca agaggucaaa gaggacauag caaaacuccu cagauacgag uccagcgccc     1500

uucccucggg ccaacuaacu agccuaagcg aauacgccuc acguaugaga gcaggcaccc     1560

gcaacaucua cuaccucugc gccccaaacc gacaccucgc agaacacuca cccuacuacg     1620

aggccaugaa aaagaaagac accgaagucc uguucugcuu ugaacaauuc gacgaacuga     1680

cccuacuaca ccucagagag uucgacaaaa agaaacucau cagcgucgag acggacaucg     1740

ucguagacca cuacaaagaa gaaaaauucg aggaccgcag cccagccgca gaaugccuau     1800

cggaaaaaga aaccgaagaa cucauggccu ggaugcggaa cguccuaggc uccagaguaa     1860

ccaacguaaa agucacacuc agacuagaca cccaccccgc cauggucacc guacuagaaa     1920

ugggagcugc ccgacacuuc cuacgaaugc aacaacuagc aaaaacacag gaggaacgcg     1980

cccaacuccu ucaaccaacc cucgaaauaa acccccgaca cgcccuaaua aagaaacuaa     2040

aucaacugag ggccuccgag cccggacucg cccaacuucu agucgaccag aucuacgaaa     2100

acgccaugau cgcggcaggc cuaguagacg acccccgcgc caugguggga cgacuaaaug     2160

aacuacuugu caaagcacua gagcgacauu aaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  4798
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt11)

<400>  4798
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaaaucu ccucccuccc cacccaacuc uucaaaugcu      120

gcuucugcga cuuccuaaaa gucaaaaugc acaccauguc cuccucccac cucuucuacc      180

uagcccucug ccuccuuacc uucaccuccu ccgccaccgc cggccccgaa acccucugcg      240

gcgccgaacu cgucgacgcc cuccaauuug ucugcggcga ccgcggauuc uacuucaaca      300

aacccaccgg cuacggcucc uccucccgcc gcgcacccca aaccggcauc gucgacgaau      360

gcugcuuccg cuccugcgac cuccgccgcc ucgaaaugua cugcgcaccc cucaaacccg      420

ccaaauccgc ccgcuccguc cgcgcccaac gccacaccga caugcccaaa acccaaaaag      480

aaguccaccu caaaaacgcc ucccgcggcu ccgccggcaa caaaaacuac cgcauguaag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  4799
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt11)

<400>  4799
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca ugggcaaauc caugcucguc cuccuaaccu      120

uccucgccuu cgccuccugc ugcaucgccg ccuaccgacc cuccgaaaca cucugcggcg      180

gcgaacucgu cgacacccuc caauucgucu gcggcgaccg cggcuucuac uucucccgcc      240

ccgccucccg cgucucacgc cgcucccgcg gcaucgucga agaaugcugc uuccgcucuu      300

gcgaccucgc ccuccucgaa accuacugcg ccacccccgc aaaauccgaa cgcgacgucu      360

ccaccccccc cacaguacuc cccgacaacu ucccccguua ccccgucggc aaauucuucc      420

aauacgacac cuggaaacaa uccacccaac gccuccgccg cggacuaccc gcccuacucc      480

gcgcccgccg cggccacguc cuagcaaaag aacucgaagc cuuccgagaa gccaaacgcc      540

accgcccccu caucgcccuc cccacccaag accccgccca cggaggcgcc ccccccgaaa      600

uggccuccaa ccgcaaauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  4800
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt11)

<400>  4800
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccaccuccgc cuucggcccc gucgccuucu      120

cccucggccu ccuacucgua cuccccgccg ccuucccagc ccccgucccc ccaggcgaag      180

acuccaaaga cgucgccgcc ccccaccgcc aaccucucac cucauccgaa cgcaucgaca      240

aacaaauacg cuacauccuc gacggcaucu ccgcccuccg caaagaaacc ugcaacaaau      300

caaacaugug cgaauccuca aaagaagccc ucgccgaaaa caaccuaaac cuccccaaaa      360

uggccgaaaa agacggcugc uuccaauccg gcuucaacga agaaacaugc cucgucaaaa      420

uaaucaccgg acuccucgaa uucgaagucu accucgaaua ccuacaaaac cgcuucgaau      480

cauccgaaga acaagcccgc gccguccaaa ugucaaccaa aguccucauc caauuccucc      540

aaaaaaaagc caaaaaccuc gacgccauca caacccccga ccccaccacc aacgccuccc      600

uacucaccaa acuccaagcc caaaaccaau ggcuccaaga caugaccacc caccucaucc      660

uccgcuccuu caaagaauuc cuccaauccu cccuccgcgc ccuccgacaa auguagggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  4801
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt11)

<400>  4801
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuccugu ggcuccgcgg auuccuccua gcaagcugcu      120

ggauaauagu acgaagcucc ccaacaccag gcagcgaggg ccacagcgcc gcacccgacu      180

gcccauccug cgcacucgcc gcccucccaa aagacguccc gaacagccaa cccgaaaugg      240

ucgaagcggu caagaaacac auacucaaca ugcuacaccu aaagaaacgc ccagacguaa      300

cacagccagu ccccaaagcc gcacuacuaa acgcgauccg aaaacuacac guaggcaaag      360

ugggagaaaa uggcuacguc gaaaucgaag acgacauagg cagacgagca gaaaugaacg      420

aacuaaugga acaaacaagu gaaauaauca cauucgccga gagcggcaca gcccggaaaa      480

cccuacacuu cgaaaucuca aaagaaggau ccgaccucag cgucguagaa cgagccgaag      540

uguggcuauu ccucaaaguc cccaaagcca acagaaccag aaccaaaguc acaaucagac      600

ucuuccaaca gcaaaaacac ccgcaaggaa gccucgacac aggcgaagaa gcagaggaag      660

ucggacucaa aggugaacgc agcgaacucc uccuguccga aaaagucguc gacgcccgaa      720

aaagcacaug gcacguauuc ccaguaagca gcuccaucca acgccugcua gaccaaggga      780

aaucaagccu ggacguccgc auagcaugcg aacaaugcca agaaagcggc gcaagccuag      840

uacuacuagg gaaaaagaaa aagaaagagg aagaaggaga aggaaagaag aaaggaggcg      900

gagaaggugg agcaggcgcc gacgaagaaa aagaacaaag ccaccggcca uuccucaugc      960

uacaagccag acaaagcgaa gaccacccac accgacgacg ccgacgaggc cucgaaugcg     1020

acggaaaagu caauauaugc ugcaagaaac aauucuucgu cagcuucaaa gacauagggu     1080

ggaacgacug gaucauagcc ccaagcggcu accacgccaa cuacugcgaa ggagaaugcc     1140

caagccacau cgccggaaca uccgggagca gccugagcuu ccacagcacg guaauaaacc     1200

acuaccgcau gcgcggccac agcccauucg ccaaccucaa aagcugcugc guacccacca     1260

aacuacgccc aauguccaug cucuacuacg acgacgggca gaacaucaua aagaaagaca     1320

uacagaacau gaucgucgaa gagugcggcu gcuccuaagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  4802
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt11)

<400>  4802
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccuac caggacgagc ccucggcgcc gcaugccucc      120

uucuccucgc cgccggaugg uuaggccccg aagcaugggg cucacccacc ccaccaccca      180

ccccagccgc acccccaccc ccacccccac caggaucccc aggaggcagc caagacacau      240

gcaccucgug cggaggcuuc agacgcccug aagaacuagg ccgagucgac ggcgacuucc      300

ucgaagccgu gaaacgccau auacucuccc gacuccaaau gcgcggccga cccaacauaa      360

cccacgccgu acccaaagca gcuaugguaa ccgcccuccg caaacuccau gccggcaaag      420

uccgagaaga cggccgaguc gaaauccccc accucgacgg acacgccucc cccggcgccg      480

acggccaaga acgaguauca gaaaucaucu ccuucgcuga aaccgacggc cuggcauccu      540

cccgaguccg ccucuacuuc uuuauaucca acgaagguaa ccaaaaccuc uucgucgucc      600

aagccucacu auggcucuac cuaaaacuac uccccuacgu acucgaaaaa ggcagccgcc      660

gcaaaguccg cguaaaaguc uauuuccaag aacaaggcca cggcgaccgc uggaacaugg      720

uagaaaaacg ugucgaccuc aaaagaucag gcuggcacac cuucccccua accgaagcua      780

uccaagcacu cuucgaacga ggagaacgaa gacucaaccu cgacguacaa ugcgacucuu      840

gccaagaacu cgcgguaguc ccaguauucg ucgaccccgg cgaagaaucc cacagacccu      900

uuguaguagu acaagcgcga cucggcgacu cucgacaccg aauccgcaaa cgcggccuag      960

aaugcgacgg acgcacaaac cucugcugcc gccaacaauu cuucauagac uuccgccuaa     1020

ucggcuggaa cgacuggauc auagccccca ccggcuacua cggcaauuac ugcgaaggcu     1080

caugccccgc auaccucgcc ggcguccccg gcucagcauc cucuuuccac accgccgucg     1140

uaaaccaaua caggaugcgc ggacuuaacc caggaacagu caauuccugc ugcauaccca     1200

ccaaacucag caccaugucc augcucuacu ucgacgacga auacaacauc gucaaacgcg     1260

acguccccaa caugaucguc gaagaaugcg gaugcgcaua aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  4803
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt11)

<400>  4803
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccuccgug uuuuacugcu cacagcacuc acacuguguc      120

acggauucaa ccuagacacc gaaaaugcaa ugaccuucca agaaaacgca cgcggcuucg      180

gacaaucggu aguccaacua caagguucgc gcguagucgu cggcgccccu caagagauag      240

ucgcugcaaa ccaacgaggc ucacucuacc aaugcgacua cucaaccggg ucaugcgaac      300

caaucagacu ccaaguccca gucgaagcag ucaacaugag ccugggucuc agccucgccg      360

ccacaaccuc acccccacaa cucuuagcau gcggaccaac cguccaucag accugcucgg      420

aaaacaccua cguaaaaggc cuaugcuuuc ucuuuggguc caaccuacga cagcagcccc      480

aaaaauuccc cgaagcccuc cgaggauguc cgcaagaaga cagcgacaua gccuuucuca      540

uugacggcuc cggauccaua auaccacacg acuuccgccg gaugaaggaa uuugucucaa      600

caguuaugga acaacucaag aaauccaaaa cacucuucuc ccugaugcaa uacagcgagg      660

aguucagaau ccacuucacc uucaaagagu uccagaacaa ccccaacccc cgcucacugg      720

uaaaaccaau aacucaacuc cucggcagga cacacacggc cacgggcauc aggaaggucg      780

ugcgcgaacu cuucaacaua acaaauggug cacgcaaaaa cgccuucaaa auccuugugg      840

ucauaaccga cggcgaaaaa uucggggacc cauuaggaua cgaagacgua auccccgaag      900

cggacagaga gggaguaauc cgauacguca ucggcguugg ggacgccuuc cguagcgaaa      960

aaucccgcca ggaacucaac acaauugccu ccaaaccgcc ccgagaccac gucuuccaag     1020

ucaacaacuu cgaagcccuc aaaaccaucc aaaaccaacu ccgagagaaa auauucgcca     1080

uagaaggaac ccaaaccggc agcuccagcu ccuucgaaca ugaaaugucc caagaaggcu     1140

ucagcgccgc gaucaccucc aacggcccuc uacucucuac cgucggauca uacgacuggg     1200

cuggcggcgu cuuccuuuac accuccaagg aaaaaucgac auucaucaac augaccagag     1260

ucgauucuga caugaacgac gcauaucucg gcuacgccgc ugcuaucauu cuacgcaaca     1320

gagugcaauc ucuaguauua ggagccccuc guuaccaaca caucggccua guggcaaugu     1380

uccgucaaaa caccgggaug ugggaaagca acgcgaacgu caagggcacc caaaucggcg     1440

cauacuucgg agcuucucuc ugcucugugg acgucgacuc aaacggaagc acugaucucg     1500

uucuuaucgg agcaccccac uacuaugagc agacucgagg aggccaagua ucagucuguc     1560

cacucccccg uggccgagcc cgcuggcaau gcgacgcggu ucuauauggc gaacaagguc     1620

aacccugggg cagguucggu gccgcgcuca ccguccuugg agacgucaac ggcgacaaac     1680

ucaccgacgu agcaaucggc gcaccuggcg aggaagacaa ccgcggcgca guguaccucu     1740

uccacggcac cuccggcagc ggcaucucac ccucccacuc acaacgcaua gccggcucua     1800

aacugucccc cagacugcaa uacuucgggc aaagccuauc cgguggacaa gaccucacga     1860

uggacggccu aguagaucug acgguuggcg cgcaagggca uguacuucua cuacgauccc     1920

aaccaguacu acgugucaag gcaaucaugg aguucaaucc acgggaaguc gcacgaaacg     1980

ucuucgaaug caacgaccaa guugucaagg gcaaagaagc cggcgaaguc agaguguguc     2040

ugcacguaca aaagagcaca cgugaucgac ugcgagaagg acaaauccag uccgugguca     2100

ccuacgaccu agcccuagac uccggaagac cccacagccg ugccgucuuc aacgaaacca     2160

aaaauucaac ccgccggcaa acccaggugc uaggccuuac ccaaacuugc gagacgcuca     2220

aacuacaacu gcccaacugu aucgaagacc cagucucacc aaucguacua cgccuuaauu     2280

uuucccuagu cggcacaccc cucucagcau ucggaaaccu ccgacccguc cucgccgaag     2340

acgcccaacg acuuuucacc gcccuauucc ccuucgaaaa gaacugcggc aacgacaaca     2400

uaugucaaga cgaccucagc aucaccuucu cuuucauguc gcucgacugc cuagugguag     2460

gcggaccccg agaauuuaac gucacaguca ccguaagaaa cgacggagag gauuccuaca     2520

gaacgcaagu uacauucuuc uucccgcucg accucucgua ccgcaaaguc ucgacccuuc     2580

aaaaccaacg aucucaacga ucuuggaggc ucgcauguga aucagccucg ucaacagaag     2640

uaaguggcgc ccucaaaucg accuccuguu ccauaaacca cccaaucuuc cccgagaaca     2700

gcgaagucac auucaacaua acauucgacg uugacucuaa agcaucacuc ggcaacaaac     2760

ucuuacugaa agccaacguc accagcgaaa acaacaugcc aagaacaaac aaaacagagu     2820

uccaacucga acucccaguc aaguaugccg uauacauggu cgucaccagc cacggaguau     2880

ccacaaaaua ccucaacuuu accgccagcg aaaacacguc cagaguaaug caacaccaau     2940

accagguauc caaccuuggu caacgcaguc uacccaucuc ccuaguguuc cucguucccg     3000

ucagacuaaa ccagacagua auaugggacc guccacaagu aacauucucu gaaaaccucu     3060

ccuccacaug ucacacuaaa gaacgacucc cuagccauuc cgacuuucuu gcagagcuuc     3120

gcaaagcccc uguugugaac ugcucaaucg cgguaugcca gcgcauacag ugcgacauac     3180

cauucuuugg gauacaggaa gaguucaacg cgacucucaa agguaaccuc agcuucgacu     3240

gguauaucaa gaccucacau aaccaccucc uaauaguauc cacagccgaa auccucuuca     3300

acgacagcgu cuucacauug cugcccggcc aaggagcuuu cguacgaucg cagacagaaa     3360

cuaaaguaga accuuucgaa gucccgaacc cgcucccgcu aaucgucgga uccuccguug     3420

gcgggcuacu ccuucuugcc cucaucacag cagcacugua uaagcucggc uucuucaagc     3480

gccaauacaa agauaugaug uccgaaggcg gcccgcccgg ggccgaaccc caguaaggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  4804
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt11)

<400>  4804
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucccuca aaaccuuacc guuccuccua cuacuacacg      120

uccaaaucuc caaagccuuc ccugucucca gcaaagagaa aaacacuaaa accguacagg      180

acuaccucga aaaauucuac caacuacccu caaaccagua ccaguccacc cgcaaaaacg      240

gcacaaacgu gaucgucgaa aagcuaaaag aaaugcaacg cuucuucggc cuaaacguca      300

caggcaaacc caacgaagaa acccucgaca ugaugaagaa accccgaugc ggcguccccg      360

acuccggcgg cuucaugcuc acacccggua accccaaaug ggaacgaacc aaccuaaccu      420

accgcauacg aaacuacaca ccccaacucu cagaagccga agucgaacga gcuaucaaag      480

acgcauuuga acucuggucc gucgcaucac cccucaucuu cacccgcauc ucucaaggcg      540

aagccgacau aaauaucgcc uucuaucaaa gagaccacgg cgacaacucc cccuucgacg      600

gcccgaacgg uauccucgca cacgccuucc aaccaggcca aggaaucggc ggcgaugccc      660

acuucgacgc agaagaaacc uggacaaaca ccucagccaa cuacaaccuc uuccucgucg      720

ccgcgcacga guucggacau ucccucggcc uagcccacuc cuccgacccc ggugcacuca      780

uguacccaaa cuacgccuuc cgcgaaacca gcaacuacuc acucccccaa gacgacauag      840

acggcaucca agccauauac ggacuaucau ccaaccccau ccagccaacc ggacccucaa      900

cccccaaacc cugcgaucca ucccucaccu ucgacgccau caccacccua cguggagaga      960

uccucuucuu caaagaucga uauuucuggc gccgacaccc ccaacugcaa cggguugaaa     1020

ugaacuucau cagccucuuc uggccuucac uacccaccgg aauccaagcc gccuaugaag     1080

acuuugaccg cgaccucauc uuccucuuca aaggaaacca auacugggcc cucucggguu     1140

acgacauccu ucaaggcuac ccuaaagaca uaucaaacua cggauuccca ucguccgucc     1200

aagccaucga ugccgcaguu uucuaccgcu ccaaaaccua cuucuucguc aacgaccaau     1260

ucuggcgcua ugacaaccaa cgccaauuca uggaaccagg auaccccaaa uccaucuccg     1320

gcgccuuccc cggcaucgaa agcaaagucg acgcagucuu ccaacaagaa cacuucuucc     1380

acguuuucuc aggcccucgc uacuacgccu ucgaccuaau cgcccaacga gucacccgag     1440

ucgcccgagg aaacaaaugg cuuaacugcc gcuacggaua gggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  4805
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt11)

<400>  4805
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucccucuggc aaccucucgu auuaguacuc cuaguccuug      120

gaugcugcuu ugccgcuccu cgacaacgcc aauccacacu cguccuuuuc ccaggggauc      180

uaagaaccaa ccuuaccgac cggcaacuag cagaggaaua ccuauaccgc uauggauaca      240

caagagucgc cgaaaugaga ggagaaucga aaagccucgg accagcccuc cuacuacuac      300

aaaaacaacu cucccugccc gaaacuggcg aacucgacuc ugccacucua aaagcaauga      360

ggaccccacg augcggcguc cccgaccuag gcagauucca aaccuucgaa ggcgaucuaa      420

aauggcacca ccacaacaua accuacugga uccaaaacua cucagaagac cucccccgag      480

ccguaauaga cgaugccuuc gcaagagcuu ucgcccucug gucggcaguc acuccccuca      540

ccuuuaccag aguauacucc cgagacgccg acauagucau ccaauucggc gucgccgaac      600

acggcgacgg cuaccccuuc gacggaaaag auggacuccu cgcucacgcg uucccaccag      660

gcccagguau ccaaggcgau gcucacuucg acgacgacga acuauggucu cucggaaaag      720

gggucgucgu ccccacccga uucggaaacg cagacggcgc cgcuugccac uuccccuuca      780

ucuucgaagg acguuccuac agcgccugca cgaccgacgg aagauccgau ggacuaccau      840

ggugcucaac gaccgccaac uacgacacag acgacagauu cggauucugu cccucagaac      900

gucucuacac acaagacggc aacgccgaug gcaaacccug ccaauucccc uucauauucc      960

aaggccaauc cuacuccgcc ugcacaaccg acggacgcuc ugacggcuac cgauggugcg     1020

cuacaacagc aaacuaugau cgagacaagu uauuuggauu cugccccacc cgcgccgauu     1080

ccaccguaau gggugggaac uccgcaggag aacucugcgu cuuccccuuc accuuccucg     1140

gaaaagagua cagcacaugc accuccgaag gccgaggcga cggccgccua uggugcgcca     1200

ccaccuccaa cuuugacuca gacaagaaau gggguuucug ccccgaccaa gguuacagcc     1260

ucuuccucgu cgccgcacau gaauuuggac acgcauuagg ccuagaccac ucgucagucc     1320

ccgaagcccu cauguacccc auguacagau ucacugaagg cccaccccuc cacaaagacg     1380

acgucaacgg aauccgccau cucuacggcc cccgaccaga accugaacca cgcccaccca     1440

caaccaccac accccaaccc accgccccac ccacugucug ccccaccggc ccacccaccg     1500

uccaucccag cgagagaccc accgcgggcc caaccggccc acccuccgca ggccccacug     1560

gacccccaac cgcaggaccc uccaccgcua cuaccguucc acuaucccca gucgacgacg     1620

cuugcaacgu caacaucuuc gacgccauag cugagauagg aaaccagcuc uaccuauuca     1680

aagacggaaa auacuggcga uucuccgagg gacgcggcuc ccgcccccaa ggaccauuuc     1740

uaauagcaga caaguggccc gcacucccac gcaaacuuga cuccguuuuc gaggaaagac     1800

ucuccaagaa acuauucuuc uuuuccggcc gacaagucug gguuuacaca ggcgccuccg     1860

uacucggucc ucgccgccuu gacaaacuag ggcucggcgc agacgucgcc cagguaacag     1920

gagcucuccg aagcggaagg ggcaaaaugu uacucuucuc cggccgucga cucuggcgau     1980

ucgacguaaa agcccaaaug guagauccca gaagcgccag cgaagucgac cgcauguucc     2040

caggaguccc ccuugauacc cacgacgucu uccaauaccg cgaaaaagcc uacuuuugcc     2100

aagaccgcuu cuacuggcgc gucucuagca gaucagaacu uaaccaagua gaccaaguag     2160

gcuacgucac cuacgacauc cuacagugcc cagaagacua aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  4806
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt11)

<400>  4806
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg uacucgcagc cuuccuauuc cuauccugga      120

cccacugccg cgcauuaccc cuccccucag gaggcgauga agacgaccuu uccgaagaag      180

accugcaauu cgccgaacgc uaccuccgau ccuacuacca ccccaccaac cucgccggca      240

uacucaaaga aaacgcagcc ucauccauga cagaacgccu ccgcgaaaug caauccuucu      300

uuggccucga agucaccgga aaacuugacg acaacacgcu agacgucaug aaaaaaccca      360

gaugcggagu ccccgacguc ggcgaauaca acgucuuccc cagaacccua aaauggucaa      420

aaaugaaccu caccuacaga auagucaacu acaccccuga caugacccac uccgaaguag      480

aaaaagccuu caaaaaagcc uucaaagucu ggucugacgu uaccccccuc aacuucaccc      540

gacuccacga cggcaucgcc gacauaauga ucuccuucgg aaucaaagaa cacggcgacu      600

ucuaccccuu cgacggacca ucaggccuac ucgcccacgc cuucccacca ggacccaacu      660

acggaggcga cgcccacuuc gaugacgacg aaaccuggac cuccuccucc aaaggcuaca      720

accucuuccu aguagccgca cacgaauucg gccacucacu aggacuagac cacuccaaag      780

accccggcgc ucuuauguuc cccaucuaca ccuacacugg gaaaucccac uucaugcucc      840

ccgacgacga cguacaaggc auccaaagcc ucuacggccc gggcgacgaa gaucccaacc      900

ccaaacaccc caaaacacca gacaaaugcg accccucacu aucacuagac gcaaucaccu      960

cccuccgugg cgaaacuaug aucuucaaag accgauucuu cuggcgcuua cacccccaac     1020

aagucgacgc cgaacucuuc cuuaccaaau cauucuggcc cgaacucccc aaccgcaucg     1080

acgccgccua cgaacacccc agccaugacc ucaucuuuau cuuccgcggg agaaaauucu     1140

gggcacuaaa cggauacgac auacucgaag gcuacccaaa aaaaaucucc gaacuaggcc     1200

ucccaaagga agucaaaaag aucuccgcag caguacacuu cgaagacacc ggcaaaaccc     1260

uccuauucuc agguaaccaa guauggcgcu acgacgacac caaccacauc auggacaaag     1320

acuacccccg ccucaucgaa gaagacuucc ccggcauagg cgacaaaguc gacgccgucu     1380

augaaaaaaa cggcuacaua uacuucuuua acggccccau ccaauuugaa uacuccauau     1440

gguccaaccg caucguacgc guuaugccag ccaacuccau ccucuggugc uaaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4807
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt11)

<400>  4807
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaccccga acaccaccga agauuacgac accacaaccg      120

aguucgacua cggcgacgcc acccccugcc aaaaagucaa cgaacgcgcc uucggcgccc      180

aacuccuccc accccuuuac ucccucgucu ucgucaucgg ccucgucggc aauauccucg      240

uaguccucgu ccucguccaa uacaaacgac ucaaaaacau gaccuccauc uaccuacuca      300

accuugccau cuccgaccuc cucuuccucu ucacccuccc cuucuggaua gacuacaaac      360

ucaaagacga cugggucuuc ggcgacgcca ugugcaaaau ccucucgggc uucuacuaca      420

caggacucua cuccgaaauc uucuucauca uccuccuaac uaucgaccgc uaccuagcca      480

ucguccacgc cgucuucgca cuacgcgccc gcaccguaac cuucggcguc aucaccucaa      540

ucaucaucug ggcccucgcc auccucgccu ccaugcccgg ccucuacuuc ucaaaaaccc      600

aaugggaguu cacacaccac acaugcucac uccacuuccc ccacgaaucc cuacgcgaau      660

ggaaacucuu ccaagcccuc aaacucaacc uauucggccu aguccuccca cuacucguca      720

ugaucaucug cuacacaggc aucaucaaaa uacuccuccg ccgccccaac gaaaagaaau      780

ccaaagcagu ccgccucauc uuugucauaa ugauaaucuu cuuccuauuc uggacccccu      840

acaaccucac cauccucauc ucaguauucc aagacuuccu cuucacccau gaaugcgaac      900

aaucacgcca cuuagaccuc gccguccaag ucaccgaggu cauugccuac acccacugcu      960

gcgucaaccc aguaaucuac gccuucgucg gcgaacgcuu ccgcaaauac cuccgucaac     1020

uauuccaccg acgcgucgcc guacaccucg ucaaauggcu ccccuuccua ucugucgacc     1080

gacuagaacg cgucuccucc acaagcccaa gcaccggcga acacgaacuc uccgccggcu     1140

ucuagggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  4808
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt11)

<400>  4808
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcacacucg ccugccuccu acuccucggc ugcggcuacc      120

ucgcacacgu ccucgccgaa gaagccgaaa ucccccgaga agucaucgaa cgacucgccc      180

gcucccaaau ccacuccauc cgcgaccucc aacgccuccu cgaaaucgac uccgucggcu      240

ccgaagacuc ccucgacacc ucacuccgcg cccacggagu ccacgccacc aaacacguac      300

ccgaaaaacg accccucccc auccgccgaa aacgcuccau agaagaagcc guccccgccg      360

ucugcaaaac ccgcaccguc aucuacgaaa ucccccgcuc ccaagucgac cccacauccg      420

ccaacuuccu caucuggccc cccugcguag aagucaaacg cugcaccggc ugcugcaaca      480

cauccuccgu aaaaugccaa cccucccgcg uacaccaccg cuccgucaaa gucgccaaag      540

ucgaauacgu ccgcaaaaaa cccaaacuaa aagaagucca gguccgccuc gaagaacacc      600

ucgaaugcgc cugcgccacc accucccuca acccagacua ccgcgaagaa gacaccggcc      660

gcccccgcga auccggcaaa aaacgcaaac gcaaacgccu gaaacccacc uaaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  4809
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt11)

<400>  4809
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaccgaugcu gggcccucuu ccucagccuc ugcugcuacc      120

uacgacuugu aucagccgaa ggcgacccaa ucccagaaga acuauacgaa augcuguccg      180

accacuccau ccgcuccuuc gacgaccucc aacgccuccu ccacggugac cccggcgaag      240

aagacggcgc cgaacuagac cuuaauauga cccgcuccca cuccggcgga gaacucgaau      300

cacucgcccg cggacgccgc ucccuaggcu cccucaccau cgccgaacca gccaugaucg      360

ccgaaugcaa aacacgcacc gaaguauucg aaaucucacg ccgacucauc gaccgcacca      420

acgccaacuu ccuugucugg cccccaugcg ucgaagucca acgcugcucc ggcugcugca      480

acaaccgcaa cguacaaugc cgacccacac aaguacaacu ccgcccaguc caaguacgca      540

aaaucgaaau cguccgcaaa aaaccaaucu ucaaaaaagc cacagucacc cucgaagacc      600

accucgccug caaaugcgaa accguagccg ccgcacgccc cgucacccgc ucacccggcg      660

gaucacaaga acaacgugca aaaacccccc aaacccgcgu cacaauccgc accguccgcg      720

uccgccgccc ccccaaagga aaacaccgca aauucaaaca cacacacgac aaaaccgccc      780

ucaaagaaac ccuaggcgcc uaaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  4810
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt11)

<400>  4810
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccucuucg gccuccuccu ccucaccucc gcccuggccg      120

gccagcgcca aggcacccag gccgaaucca accucuccuc caaauuccaa uucuccucca      180

acaaagaaca aaacggcguc caagaccccc aacacgaacg aaucaucacc gucucaacaa      240

acggcucaau acacucacca cgcuuccccc acaccuaccc aagaaacacc guccucgucu      300

ggcgccuagu cgccgucgaa gaaaacguau ggauccaacu caccuucgac gaacgcuucg      360

gccucgaaga cccagaagac gacaucugca aauacgacuu cguagaaguc gaagaaccua      420

gcgacggcac cauacucgga cguuggugcg gcuccggcac cguccccggc aaacaaaucu      480

ccaaaggcaa ccaaauccga auacgcuucg uauccgacga auacuuccca uccgaacccg      540

gcuucugcau ccacuacaac aucgucaugc cccaauucac cgaagccguc ucccccuccg      600

uacuaccccc cuccgcccuc ccccucgauc uucucaacaa cgccaucacg gccuucucca      660

cccucgaaga ccuaauacgc uaccuggaac ccgaaagaug gcaacucgau cucgaagauc      720

uauaccgccc cacauggcaa cuccucggca aagccuucgu cuucggcaga aaaucccggg      780

ucguagaccu caaccuccuc accgaagaag uacgccuaua cuccugcaca ccacgcaacu      840

ucuccguauc cauccgagaa gaacucaaac gcaccgacac uaucuucugg cccggcugcc      900

uccucgucaa aagaugcggc ggaaacugcg ccugcugucu ccacaacugc aacgaaugcc      960

aaugcguccc cuccaaagua accaaaaaau accacgaagu ccuacaacuu cgcccaaaaa     1020

ccggcguaag aggccuccac aaaucccuca ccgacgucgc acuagaacac cacgaagaau     1080

gcgacugcgu cugccgcggc uccaccggag gauaaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  4811
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt11)

<400>  4811
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgccuaa ucuucgucua cacccuaauc ugcgccaacu      120

ucugcuccug ccgagacacc uccgccaccc cacaauccgc cuccauaaaa gcacuccgga      180

augccaacuu acgccgggac gaccuauacc gucgagacga aacaauccaa guaaaaggaa      240

acggcuacgu gcaaucgccc cgauucccaa acuccuaccc acgcaaccuc cuccucaccu      300

ggcgacuaca cucccaagaa aacacucgca uccaacucgu cuucgacaac caguucggcc      360

uggaagaagc cgaaaacgac aucugccgcu acgacuucgu cgaagucgaa gacauaucag      420

aaaccuccac caucauacgc ggccgcuggu gcggccacaa agagguaccc ccccgcauca      480

aaucccgcac aaaccaaauc aaaauaaccu ucaaaucaga cgacuacuuc guagcuaaac      540

ccggauucaa aaucuacuac ucccuccuag aagacuucca acccgccgca gcauccgaga      600

ccaacuggga auccguaacc uccuccauau ccggcguauc cuacaacagc cccuccguca      660

cagaccccac ccuuauagcc gacgcccucg acaaaaaaau cgccgaauuc gacaccgucg      720

aagaucuccu aaaauacuuc aaccccgaau cauggcaaga agaccucgaa aacauguacc      780

uagacacccc acgauaccgc ggacgcucau accacgaccg aaaauccaaa gucgaccucg      840

accgacucaa cgacgacgcc aaacgcuaca gcugcacacc acgcaacuac uccgucaaca      900

uccgcgaaga gcuaaaacuc gccaacguag ucuucuuccc ccgcugccuu cucguccaaa      960

gaugcggcgg caacugcggc uguggaaccg uaaacuggcg cagcugcacc ugcaacucag     1020

gcaaaaccgu caaaaaauac cacgaagucc uccaauucga accaggccac aucaaacgcc     1080

gcggccgagc caaaacaaug gcccucgucg acauccagcu cgaccaccac gaacgcugcg     1140

acugcauaug cuccagccgc cccccucgcu aaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  4812
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt11)

<400>  4812
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccacu ccaaauuccc ugccgcaggc augucccgac      120

cccucgacac cucccuccga cucaaaaccu ucuccucaaa guccgaauac caacucgucg      180

ucaacgccgu ccguaaacuc caagaauccg gcuucuacug guccgccguc accgguggug      240

aagcaaaccu ccuccucucc gcagaacccg ccggcaccuu ccucauccgc gacuccucag      300

accaacgcca cuucuucacc cucucaguca aaacccaauc cggcaccaaa aaccuccgca      360

uccaaugcga aggcggcucc uucucccucc aauccgaccc acgcuccaca caaccugucc      420

cacgcuucga cugcguccuc aaacucgucc accacuacau gccacccccc ggcgcccccu      480

ccuucccauc cccccccacc gaacccuccu cagaaguccc cgaacaaccc ucagcccaac      540

cccuccccgg cucccccccc cgccgcgcau acuacaucua cuccggcggc gaaaaaaucc      600

cacucguacu cucccgcccc cucuccucca acgucgccac ccuacaacac cucugccgca      660

aaaccgucaa cggccaccuc gacuccuacg aaaaagucac ccaacuaccc ggccccaucc      720

gcgaauuccu cgaccaauac gaugcacccc uauaaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  4813
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt11)

<400>  4813
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guccccuccg ccggccaacu cgcccuauuc gcccucggaa      120

ucguccucgc agccugccaa gcccucgaaa acuccaccuc cccccucucc gccgaccccc      180

ccgucgccgc cgccgucguc ucccacuuca acgacugccc cgacucccac acccaauucu      240

gcuuccacgg caccugccgc uuccucgucc aagaagacaa acccgccugc gucugccacu      300

ccggcuacgu cggcgcccgc ugcgaacacg ccgaccuccu cgccgucguc gccgccuccc      360

aaaaaaaaca agccaucacc gcccucgucg ucgucuccau cgucgcccuc gccguccuca      420

ucaucaccug cguccuaauc cacugcugcc aaguccgcaa acacugcgaa uggugccgcg      480

cccucaucug ccgccacgaa aaacccuccg cccuccucaa aggccgcacc gccugcugcc      540

acuccgaaac agucguuuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  4814
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt11)

<400>  4814
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucccucug gccuucgacu gcucccccuc cuccuccccc      120

uccuauggcu ccuaguccua acacccggcc gcccagccgc aggccucucc acaugcaaaa      180

caauagacau ggaacucguc aaacgaaaac gcaucgaagc aauccgcggc caaauacucu      240

cuaaacuucg ccucgccuca ccacccuccc aaggcgaagu cccaccagga ccccuccccg      300

aagccguauu agcucucuac aacuccacac gcgaccgcgu cgcaggcgag agcgccgaac      360

ccgaacccga accugaagcu gacuacuacg ccaaagaagu aacacgcguc cucaugguug      420

aaacccacaa cgaaaucuau gacaaauuca aacaauccac ccacucaauc uacauguucu      480

uuaacacauc agaacuccgc gaagccgucc ccgaaccagu ccuccuuucc cgugccgaac      540

uccgccuacu gcgccucaaa cuaaaaguag aacaacacgu ugaacucuac caaaaauacu      600

caaacaauuc cuggcgauac cucuccaacc gccuccucgc ccccuccgac agccccgaau      660

ggcucucuuu ugacgucaca ggcgucguac gccaauggcu cucaagaggc ggcgaaaucg      720

aaggcuuccg ccucucagcc cauugcucuu gcgacucucg cgacaacacc cuccaagucg      780

acaucaacgg cuucaccacc ggccgacgcg gcgaccucgc caccauccac ggcaugaacc      840

guccuuuccu acuucuaaug gccacacccc ucgaacgcgc ccaacaccuc caaucaucac      900

gccacagacg cgcccucgac accaacuacu gcuucuccuc caccgaaaag aacugcugcg      960

uacgccaacu cuacaucgac uuccguaaag accucggcug gaaauggauc cacgaaccca     1020

aaggcuacca cgccaacuuc ugucuuggcc caugccccua caucuggucc cuagacacuc     1080

aauacuccaa aguccuagcc cuuuacaacc aacacaaccc cggcgcauca gccgcccccu     1140

gcugcguacc ccaagcccuc gaaccacucc ccauagucua cuacguaggc cgaaaaccca     1200

aagucgagca acuauccaac augaucgucc ggucgugcaa augcuccuaa ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  4815
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt11)

<400>  4815
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uccucuccgc cuuccucaua uuacaccucg      120

ucaccguugc ccuaucccuc ucgacuugcu ccacccucga cauggaccaa uucaugcgca      180

aaagaaucga agcaauccga ggccaaaucc ucucaaaacu caaacuuaca ucccccccug      240

aagacuaucc agaacccgag gaaguccccc cugaagucau auccauauac aacagcaccc      300

gcgaccuacu ccaagaaaaa gccucgcgac gagccgcagc cugcgaacgc gaacgcagcg      360

acgaagaaua cuacgccaag gaagucuaca aaaucgacau gccgcccuuc uucccaucag      420

agaaugcuau cccccccacc uucuaccgac cauacuuccg caucguccgc uucgacgucu      480

ccgcaaugga aaaaaacgcc uccaaccucg ucaaagccga auuccgcguc uuccgccugc      540

aaaaccccaa agcccgcguu cccgaacaac gcaucgaacu cuaccaaaua cucaaaucca      600

aagaccucac cucucccacc caacguuaca ucgacucuaa aguagucaaa acacgcgccg      660

aaggcgaaug gcucuccuuc gacguaaccg acgccguaca cgaauggcuc caccacaaag      720

acagaaaccu cggauucaaa aucucccuac acugccccug cugcacuuuc guccccucca      780

acaacuacau aauucccaac aaauccgaag agcuugaagc ccgcuucgcc ggcaucgacg      840

gaaccucgac cuacacuuca ggcgaccaga aaaccauuaa auccacccgc aaaaaaaacu      900

cgggcaaaac accccaccuc cuacucaugc uccucccauc cuaccggcua gaaucccaac      960

aaaccaaccg acgcaaaaaa cgagcccucg acgcagccua cugcuuccgu aacguccaag     1020

acaauugcug ccuacgccca cucuacaucg auuucaaacg ugaccucgga uggaaaugga     1080

uccaugaacc caaaggcuac aacgccaacu ucugcgcagg cgcaugcccc uaccucugga     1140

gcuccgacac ccaacacucc cgcguccuaa gccuuuacaa caccaucaac cccgaagccu     1200

cagccucccc cugcugcguc ucccaagacc ucgaaccacu aacaauccuc uacuacaucg     1260

gcaaaacccc caaaauagaa caacucucca acaugaucgu caaauccugc aaaugcuccu     1320

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  4816
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt11)

<400>  4816
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaugcacc uccaacgagc ccuagucguc cucgcacuac      120

ucaacuucgc aaccgucucc cuaagccuuu ccacaugcac cacccuggac uucggccaca      180

ucaaaaagaa acgugucgaa gccauucgag gccaaauacu cagcaaacuc cgccucacau      240

cacccccaga acccacaguu augacccacg uccccuacca gguccuagcc cuauacaaca      300

gcacccgcga acuccucgaa gaaaugcacg gcgaacgcga agaaggcugc acccaagaaa      360

auacagaguc cgaauauuau gcaaaagaaa uccacaaauu cgacaugauc cagggccucg      420

ccgaacacaa cgagcucgcc gucuguccca aaggcaucac cuccaaagua uucagauuca      480

acgugucauc cgucgagaaa aaccgcacca accucuuccg cgccgaguuc cguguccucc      540

gcgucccaaa ccccuccagc aaacgaaacg aacaacgaau agaacuauuc cagauccucc      600

gccccgacga acacaucgcc aaacaacgcu acauuggggg caaaaaccuc cccacccgcg      660

gaacagccga auggcuaucc uucgacguca ccgacaccgu ccgcgaaugg cuacuaagaa      720

gagaauccaa ccucggccuc gaaaucucca uacacugccc cugccacacc uuccaaccca      780

acggagacau acucgaaaac auccacgaag uaauggaaau caaguucaaa ggagucgaca      840

acgaagacga ccacggccgc ggcgaccuag gccgccucaa aaagcagaaa gaccaccaca      900

acccccaccu aauacuaaug augauacccc cucaccgccu cgacaacccc ggccaaggcg      960

gacaacgcaa aaagcgcgcc cucgacacua acuacugcuu ccgcaaccuc gaagaaaacu     1020

gcugcguccg cccccucuac aucgacuucc gccaagaccu cggguggaaa uggguacacg     1080

aacccaaagg cuacuacgcc aacuucugca gcggaccaug cccauaccuc agaagcgcag     1140

acacaacaca cuccaccguc cucggccucu acaacacccu aaaccccgaa gccucagccu     1200

cccccugcug cguaccacaa gaccuugaac cacucaccau ccucuauuac guaggccgca     1260

cccccaaagu cgaacaacuc ucaaacaugg ucguaaaauc augcaaaugc uccuaaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4817
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt11)

<400>  4817
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaccagucg cagucugggc cgcccucgcc guaggccuug      120

aacucugggc agccgcccac gcccucccag cacaagucgc auucacuccc uacgcacccg      180

aacccggcuc caccugccgc cuacgcgaau acuaugacca aacagcacaa augugcugcu      240

ccaaaugcuc ucccggccaa cacgcuaaag uauucugcac aaaaaccucu gacaccguau      300

gcgacucaug cgaagacucc acauauaccc aacucuggaa cugggucccc gaaugccucu      360

ccugcggcuc ccgcugcagc ucagaccaag uagaaaccca agcuugcacc cgcgagcaaa      420

accgcaucug cacaugccgc cccggcuggu acugcgcucu cuccaaacaa gaaggcugca      480

gacuuugugc accucugagg aaaugccgac caggcuuugg uguagcaaga cccgguaccg      540

aaaccucaga cgucgucugc aaaccgugug cacccggcac cuucucaaac accaccuccu      600

cuaccgacau cugccgacca caucaaaucu gcaacguagu cgccauccca ggcaacgccu      660

ccauggacgc cguaugcacc ucgaccuccc ccacccgcuc cauggccccc ggcgccguac      720

accuacccca acccgucucc acccgauccc agcacaccca acccacccca gaacccagca      780

ccgccccguc aaccucauuc cuacucccaa ugggccccuc cccacccgca gaaggcucca      840

caggcgauuu cgcccucccc guaggacuaa uaguuggcgu caccgcccua ggccuccuua      900

ucaucggcgu agucaacugc gucaucauga cccaagucaa aaaaaaaccc cucugccucc      960

aacgcgaagc caaaguccca caccucccag ccgacaaagc ccgcggaacc caaggccccg     1020

aacaacaaca ccugcucauc accgcccccu caucaagcuc cuccucacuc gaaucauccg     1080

ccuccgcccu cgaucgacgc gcccccacac gcaaccaacc acaagcccca ggcguagaag     1140

cguccggcgc cggcgaagcc cgcgccucca ccggcucguc cgacuccuca ccaggagguc     1200

acggcaccca aguaaauguc accugcaucg ugaacguuug uuccuccuca gaucacagcu     1260

cccaaugcuc uucccaagcc uccuccacaa ugggcgacac cgauuccagc cccucagaau     1320

cccccaaaga cgaacaaguc ccauucucaa aagaagagug ugccuuccga ucccagcucg     1380

aaacaccaga aacccuacuc gguucaaccg aagaaaaacc ccucccccuc ggcgucccag     1440

acgcaggcau gaaacccucc uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  4818
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt11)

<400>  4818
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggucaugc gccuguuccc gugcuuucuc cagcuacugg      120

ccgggcucgc gcucccggcc gugcccccgc aacaaugggc gcucucggcc ggaaacggga      180

gcucggaagu ggaagugguc ccguuccagg aagugugggg gcgcucguac ugucgagcgc      240

ucgagcgcuu ggucgauguc gugagcgagu acccgagcga ggucgagcac auguucucgc      300

ccucgugcgu gagcuugcua aggugcacgg gauguugcgg ggacgagaac uugcacugug      360

uaccggucga gaccgcgaac gugaccaugc aauugcucaa gaucaggagc ggggacaggc      420

ccucguacgu ggaauugacc uuuagccagc acgugcgcug ugaaugucgc ccgcucaggg      480

aaaagaugaa gccagagcgc aggcgcccga aagggcgagg gaaaaggcgc agggaaaagc      540

aaagacccac ggacugucac uugugcgggg acgcgguccc gaggcgcuga ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  4819
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt11)

<400>  4819
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgauagac agaccgacac agcgcccuca cccucguacc      120

aucucuugcc ggggaggagg agaacgguag acgcggcggc aucgcgcggg caagggccgg      180

aaccagcgcc agggggagga gucgaaggag ugggagcgag aggggucgcg cuaaaacucu      240

ucguccaacu gcugggaugc agcagguucg ggggagcagu gguaagagca ggagaggcag      300

agccaucggg cgcggcaagg agcgcaagcu cgggaaggga ggaaccacag ccagaagaag      360

gggaagagga agaggaaaag gaagaagaaa ggggaccaca auggagacua ggcgcgagaa      420

agccagggag cuggacaggg gaggcggccg ugugcgcgga cucggcacca gccgcaagag      480

cgccgcaggc acuagcaagg gccucgggaa ggggaggaag gguggcaaga cgaggagccg      540

aggaaucagg accaccacac agcccaagca ggcgagggag cgcgagcagg gcagggcccg      600

ggagagcaag cgagacaaug aacuuucucu ugagcugggu acauuggucg cuagcgcucc      660

uacuguaucu gcaccacgcg aaauggagcc aggcagcgcc aauggcagag ggaggagggc      720

agaaccacca cgaagucgug aaauucaugg auguauacca aaggagcuac ugccacccaa      780

uagaaacgcu aguagacaua uuccaggaau auccagauga aauugaauac auauucaaac      840

cgagcugcgu accacucaug agguguggcg gaugcuguaa cgaugaaggg cuagagugcg      900

ugccaacaga agagagcaac auaacaaugc aaauaaugcg aauaaaacca caccaaggac      960

agcacauagg agagaugagc uuccuacaac acaacaagug cgagugcagg ccaaagaaag     1020

acagagcgcg ccaagaaaag aaaagcguaa ggggaaaggg gaagggacag aaaaggaaaa     1080

ggaaaaagag uagauacaaa aguuggagcg uauacguagg agcgagaugc ugcuugaugc     1140

cguggucacu accgggacca cacccgugug ggcccugcag cgagagacga aaacaccuau     1200

ucgugcagga cccgcagacg ugcaagugcu cguguaagaa cacggacucg aggugcaaag     1260

cgagacagcu agagcugaau gaaaggaccu gccgauguga caagcccaga agguagggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4820
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt11)

<400>  4820
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc uaagcugggu ccacuggucc cucgcccuac      120

uccucuaccu acaccacgcc aaaugguccc aagccgcacc cauggccgaa ggcggcggcc      180

aaaaccacca cgaagucguc aaauucaugg acgucuacca acgcucauac ugccacccca      240

ucgaaacccu cgucgacauc uuccaagaau accccgacga aauagaauac aucuucaaac      300

ccucaugcgu cccccucaug cgcugcggcg gcugcugcaa cgacgaagga cucgaaugcg      360

uacccaccga agaaucaaac aucacaaugc aaaucaugcg caucaaaccc caccaaggcc      420

aacacaucgg cgaaaugucc uuccuccaac acaacaaaug cgaaugccgc cccaaaaaag      480

accgagcacg acaagaaaaa aaauccgucc gaggcaaagg caaaggccaa aaacgaaaaa      540

gaaaaaaauc ccgcuacaaa uccugguccg uauacgucgg cgcccgaugc ugccucaugc      600

cauggucccu ccccggcccc cacccaugcg gccccugcuc cgaacgccgc aaacaccucu      660

ucguccaaga cccccaaacc ugcaaaugcu ccugcaaaaa caccgacucc agaugcaaag      720

cccgccaacu cgaacucaac gaacgcaccu gccgcugcga caaaccccga cgcuaaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  4821
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt11)

<400>  4821
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccccccucc uccgccgccu ccuccucgca gcccuacucc      120

aacuagcccc cgcacaagcc cccgucuccc aacccgacgc ccccggccac caacgcaaag      180

uagucuccug gauagacguc uacacccgcg ccaccugcca accccgcgaa gucguagucc      240

cccucacagu cgaacucaug ggcacagucg ccaaacaacu cguacccuca ugcgucaccg      300

uccaaagaug cggcggcugc ugccccgacg acggccucga augcgucccc accggccaac      360

accaaguccg caugcaaaua cucaugaucc gauacccauc aucccaacua ggagaaaugu      420

cacucgaaga acacucucaa ugcgaaugca gacccaaaaa aaaagacuca gccguaaaac      480

cagaccgcgc cgcaacaccc caccaccgcc cccaaccacg aucagucccc ggcugggacu      540

ccgcccccgg cgcccccucc cccgccgaca ucacccaccc cacccccgcc cccggcccau      600

ccgcccacgc cgcccccucc accaccucug cccuaacccc cggccccgcc gccgccgccg      660

cagacgccgc cgccucaucc gucgccaaag gcggcgccua aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  4822
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt11)

<400>  4822
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuccuag gcuucuucag cguugccugc ucccuacugg      120

ccgccgcccu ccucccuggc ccccgcgaag cucccgcagc cgcagcagcc uuugaaucag      180

gucucgaccu uagcgacgca gaacccgacg ccggagaagc uaccgccuac gcgagcaaag      240

accucgaaga acaacugcga uccgucuccu ccgucgacga acucaugacu guacucuacc      300

ccgaauacug gaaaauguac aaaugccaac uccggaaagg aggcuggcaa cacaacagag      360

aacaagccaa ccucaacucc cgaaccgaag aaacuaucaa auucgccgca gcccacuaca      420

acaccgaaau acucaaauca aucgacaacg aauggagaaa aacccaaugc augccccgag      480

aagucugcau cgacgucggc aaagaguucg gagucgccac caacacauuc uucaaaccac      540

cuuguguauc cgucuaccga ugcggagguu gcugcaacuc cgaaggccua caaugcauga      600

acaccuccac cucauaccuc ucaaaaacac ucuucgaaau caccgucccc cuaagccaag      660

gcccgaaacc agucaccauu uccuucgcaa accauacauc augccgaugu augucaaaac      720

ucgacgucua ccgccaaguc cacuccauaa uccgacgcuc acucccagcc acccuccccc      780

aaugccaagc agcaaacaaa accugcccaa ccaacuacau guggaacaac cacaucugcc      840

gcugccucgc acaagaagac uucauguuca gcuccgacgc cggcgacgac uccaccgacg      900

gcuuccacga caucugcggc cccaacaaag aacucgacga agaaacaugc caaugcguuu      960

gucgcgccgg ccuccgccca gccuccugcg gaccacacaa agaacucgac agaaacuccu     1020

gccaaugcgu uugcaaaaac aaacuauucc caucccaaug cggagccaac cgcgaguucg     1080

acgaaaauac cugccaaugc guaugcaaac gaaccugccc ccgaaaccaa ccccuaaacc     1140

ccggcaaaug cgcuugcgaa ugcaccgaau ccccgcaaaa augccuccuc aaaggaaaga     1200

aauuccacca ccaaaccugc uccugcuacc gccgacccug caccaaccgu caaaaagcgu     1260

gcgaacccgg auucuccuac uccgaagaag ucugccgcug cguccccagc uacuggaaac     1320

gcccccaaau guccuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  4823
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt11)

<400>  4823
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uaccgagaau gggucgucgu caacguauuc augaugcucu      120

acguacaacu cguccaaggc agcagcaacg aacacggccc cgucaagaga uccagccaaa      180

gcacccuaga acgauccgaa caacaaauac gcgcagccuc aagccucgaa gaguuacuac      240

gaaucaccca cucagaagac uggaagcucu ggcgaugccg ccuccgccuc aaguccuuca      300

ccuccaugga cagcagauca gccucccacc gcucaacccg uuucgccgcc accuucuacg      360

acaucgaaac ccucaaaguc aucgacgagg aauggcaacg aacacaaugc ucucccagag      420

aaaccugcgu agaagucgcc uccgaacuug guaaaucaac caacacuuuc uucaaaccac      480

ccugcgucaa cgucuuccgc ugcggaggcu gcugcaacga agagucccuc auaugcauga      540

acacauccac cuccuacauc uccaaacaac ucuucgaaau auccguaccc cuaaccuccg      600

ucccagaacu uguacccguc aaagucgcca accacaccgg cugcaaaugc cuccccacag      660

caccccgcca ccccuacucc auaauccgcc gaucgauaca aauaccggaa gaagaccgcu      720

gcucacacuc aaagaaacuc ugccccauag acaugcucug ggacuccaac aaaugcaaau      780

gcguccucca ggaagaaaac ccccuagccg gcacagaaga ccacucccac cuccaagaac      840

cagcccucug cggcccccau augauguucg acgaagaccg cugcgaaugc guaugcaaaa      900

cccccugccc caaagaccuc auccaacacc ccaaaaacug cucaugcuuc gaaugcaaag      960

aaucacucga aaccugcugc caaaaacaca aacucuucca ccccgacaca ugcucaugcg     1020

aagaccgaug ccccuuccac acccgccccu gcgccuccgg caaaaccgcc ugcgccaaac     1080

acugccgauu cccaaaagaa aaacgcgccg cccaaggccc ccacucacgc aaaaauccau     1140

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  4824
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt12)

<400>  4824
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gauuccgacg aaaccggcuu ugaacacuca ggauuauggg      120

uaucaguauu agcaggacua cuacuaggag caugccaagc acacccaaua ccagacucau      180

caccauuauu acaauucgga ggacaaguaa gacaaagaua ccuauacaca gacgacgcuc      240

aacaaacaga agcacauuua gaaauaagag aagacggaac aguaggaggc gcagccgacc      300

aaucaccaga aucuuuacua caauuaaaag cacuaaaacc aggcguaaua caaauauuag      360

gaguaaaaac aucaagauuc uuaugccaaa gaccagaugg agcacuauac ggaucacuac      420

acuuugaccc agaagcaugc ucauucagag aauuacuauu agaagacgga uauaacguau      480

accaaucaga agcacaugga cuaccccuac accuaccagg aaacaaauca ccacaucgag      540

acccagcccc aagaggcccc gcaagauucc uaccacuacc aggacuacca ccagcacuac      600

cagaaccacc aggaauauua gcaccacaac caccagaugu aggauccucc gacccauuau      660

caaugguagg accaucacaa ggaagaucuc caucauacgc aucauaagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  4825
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt12)

<400>  4825
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauucauucc caccucuauu acuacuauua uuuuggggug      120

uuguauccca cucauuucca gcuacauuag aaacacaaga acaagacgua gaucuagucc      180

aaaaauaucu agaaaaauac uacaaccuaa aaaacgacgg acgccaagua gaaaaaagaa      240

gaaacagugg accaguagua gaaaaacuaa aacaaaugca agaauuuuuu ggacuaaaag      300

ucacaggaaa accugaugcc gaaacuuuaa aaguaaugaa acaaccaaga ugcggcguac      360

cugacguagc acaauucguc uuaacagaag gaaacccaag augggaacaa acgcacuuaa      420

cauaucgaau cgaaaauuac acaccagacc uaccaagagc agacguagau cacgcaauag      480

aaaaagccuu ccaacuaugg ucaaauguaa caccccuaac auucacaaaa guaucagaag      540

gacaagcaga uauaaugauc ucauucguaa gaggggauca cagagauaac ucacccuucg      600

auggcccagg aggaaaccua gcacacgcau uccaaccugg accaggaaua gguggugaug      660

cacauuucga cgaagacgaa agauggacaa acaacuucag agaauauaac cuacacagag      720

uagcagcuca cgaacuaggu cauucauuag gacuaaguca uucaacagau auaggagcac      780

uaauguaccc aucauacacu uuuagcggag acguacaacu agcacaagac gacauagaug      840

gaauacaagc aauauacgga agaucacaaa accccguaca accaauagga ccacaaacac      900

caaaagcaug ugacucaaaa cucaccuucg acgcaauaac aaccauaaga ggagaaguua      960

uguucuuuaa agacagauuc uacaugagaa caaaucccuu uuacccagaa guagaauuaa     1020

acuucaucuc aguauuuugg ccccaacuac caaauggucu agaagcagcc uacgaauuug     1080

cugauagaga ugaaguaaga uucuucaaag gaaacaaaua uugggccguc caaggacaaa     1140

acguauuaca cggauaucca aaagauaucu acuccucauu cggcuuucca agaacaguaa     1200

aacauauuga ugcagcacua uccgaagaaa acacaggaaa aacauacuuc uuuguagcca     1260

acaaauacug gagauaugau gaauacaaaa gaucgaugga cccaggauac cccaaaauga     1320

uagcacacga cuuuccagga auaggacaca aaguagaugc aguauucaug aaagacggau     1380

ucuucuacuu cuuccacggc accagacaau acaaauuuga ccccaaaaca aaacgcaucc     1440

uaacauuaca aaaagcaaau ucaugguuua acuguagaaa aaacuaagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  4826
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt12)

<400>  4826
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacucauucc caccacuauu auuacuacua uucuggggag      120

uaguaucaca cuccuucgua uuaacugaag gaaauccucg augggaacaa acccaccuca      180

cauauagaau agaaaacuac acaccagacc uaccuagagc agacguagac cacgcaauag      240

aaaaagccuu ccaauuaugg uccaacguca caccauuaac uuucacuaaa gucucagaag      300

gacaagcaga uauaaugaua uccuuuguca gaggagauca cagagacaac ucaccauuug      360

acggaccagg aggaaaucua gcacacgcau uccaacccgg acccggaaua gguggagacg      420

cacacuucga ugaagaugaa agauggacaa acaauuucag agaauacaau uuacacagag      480

uagcagcaca cgaacucgga cacuccuuag gacucuccca uucaaccgac auaggagcau      540

uaauguaccc aucauacaca uucucaggag acguccaacu agcacaagac gauaucgacg      600

gcauacaagc uauauacgga agaucacaaa acccaguaca accaaucgga ccacaaacac      660

caaaagccug ugacucaaaa uuaacuuuug augcaaucac aacuauacga ggcgaaguaa      720

uguuuuucaa agacagauuc uacaugagaa caaaccccuu uuacccugaa guagaacuaa      780

acuucauauc uguuuucugg ccacaacuac caaacggauu agaagcagca uacgaauuug      840

ccgacagaga cgaaguuaga uucuucaaag gaaacaaaua cugggcaguu caaggacaaa      900

acgucuuaca cggauaucca aaagauauau acuccucauu cggauuccca agaaccguaa      960

aacacaucga ugccgcauua ucagaagaaa auacaggcaa aacauacuuc uuuguugcaa     1020

acaaauauug gagauacgac gaauacaaac gcucuaugga cccaggcuau ccaaaaauga     1080

uugcacacga uuucccagga auaggacaca aaguagaugc aguauucaug aaagacggau     1140

ucuuuuauuu cuuccacgga acaagacaau acaaauucga uccaaaaaca aaaagaaucc     1200

uaaccuuaca aaaagccaac ucaugguuca auugcagaaa aaauuaagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  4827
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt12)

<400>  4827
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaaaaaca uacugaaaau cuuaauggac uccuacucca      120

aagaaucaaa aauccaaaca guaagacgug uaacaucagu aucacuccug gcaguauacc      180

uuacaaugaa cacuucuucc uuaguauuag ccaaaccaau agagaauacu aaugacacau      240

caaucaaaaa uguagaaaaa uuacgaaaug cacccaacga agaaaacagc aagaaaguag      300

aagauuccaa aaacgacaaa guagaacaug uuaaaaacau agaagaagcu aaaguagaac      360

aaguugcucc ggaagugaaa ucaaaaucaa cguugagaag ugcaaguaua gcaaacacca      420

acuccgaaaa auaugacuuc gaauacuuaa auggacuauc guacacagaa uuaacaaauu      480

uaauuaaaaa cauaaaaugg aaucaaauaa auggucuguu caacuauagu accggcuccc      540

aaaaauucuu cggagauaaa aaucguguuc aagcuauaau aaaugcacua caagaaucug      600

guagaacaua uaccgcuaac gauaugaaag gaauagagac uuuuacggaa guccuaagag      660

ccggauucua cuuaggauac uauaacgaug guuuaaguua uuuaaaugac agaaauuuuc      720

aagacaaaug cauaccggca augauagcaa uacagaaaaa cccuaacuuu aagcuaggaa      780

cagcugucca agacgaagua auuacaucac uagguaaacu uaucggaaau gcaagcgcaa      840

acgcagaagu cguaaauaau ugugucccag uacuaaaaca auuuagagaa aauuuaaacc      900

aauaugcucc agacuaugua aaaggaacag caguaaauga acuuauaaaa gguauagagu      960

ucgacuucuc aggagcagca uaugaaaaag acguaaaaac aaugccaugg uauggaaaaa     1020

ucgauccauu uauaaaugaa uugaaggcau uaggccuaua uggaaauaua accagcgcga     1080

cagaaugggc aucagacguc ggaauuuacu accuuaguaa auucggacua uauagcacaa     1140

auagaaauga cauaguacaa agccucgaaa aagcgguaga uauguacaaa uauggaaaaa     1200

uagcuuucgu agccauggaa cgaauaacau gggacuauga ugguauaggu ucaaacggaa     1260

agaaagucga ccacgauaaa uuccuagacg augcugaaaa acacuacuua ccaaaaaccu     1320

acacguucga uaauggaacu uuuauaauac gugcuggaga caaaguuuca gaagagaaaa     1380

ucaaaagauu auauugggcu ucgcgagaag uaaaaucuca auuccaccga guaguaggaa     1440

acgauaaagc auuagaaguu ggaaaugcgg acgauguauu aacaaugaaa auuuucaacu     1500

cacccgaaga auauaaauuu aauacuaaca uuaacggugu aagcacagau aacggagguu     1560

uauacauaga accucgagga acauuuuaua cguaugaacg aacaccacaa caaagcauau     1620

uuucguuaga agaacuauuu agacaugaau auacacauua ccuacaagca cgauacuuag     1680

uagauggauu auggggucaa ggacccuuuu acgaaaagaa ucgccucaca ugguucgaug     1740

aaggcaccgc ugaguucuuu gcuggcucga cgagaacaag uggagugcuc ccaagaaaaa     1800

guaucuuagg auaccuugca aaagauaagg uugaccaucg uuauucacua aagaaaacuu     1860

uaaauucagg uuacgacgac agugauugga uguuuuacaa uuacggauuu gcaguagcac     1920

auuaucucua cgaaaaagac augcccaccu uuauaaaaau gaauaaagca auuuuaaaca     1980

ccgauguaaa auccuacgau gaaauaauua agaaacugag ugaugacgcc aacaaaaaua     2040

ccgaauauca aaaucacauc caagaauuag ccgacaaaua ccaaggagca gguauaccgc     2100

uagugaguga ugacuaucuc aaagaccacg gcuauaagaa agcaucugaa guuuacuccg     2160

aaauuagcaa agcggcauca cucaccaaua cuagcgucac cgcagaaaaa ucccaauacu     2220

uuaauacauu uacucuucga ggcacauaca caggagaaac gagcaaagga gaauuuaaag     2280

acugggacga aaugaguaag aaacucgaug gaacauuaga aucauuagcc aaaaacuccu     2340

ggaguggcua caaaacacuu acugcauacu ucacaaauua uagaguaaca agugauaaua     2400

aaguacaaua ugauguaguc uuucacggug uauuaacaga uaaugcagau auaucaaaca     2460

acaaagcacc aauagcaaaa guaacuggac caucaacagg ggcugucggg agaaauauug     2520

aguucucagg caaagauuca aaagacgaag augguaaaau uguuucguac gauugggauu     2580

uuggcgacgg agcaacaagu cgugguaaaa acaguguaca ugccuacaag aaagccggaa     2640

ccuacaaugu aacauuaaaa guaaccgacg acaaaggagc aaccgccaca gaaaguuuua     2700

cuauagaaau uaaaaaugaa gacacaacaa cccccauaac uaaagaaaug gaaccaaacg     2760

acgacauaaa agaagcaaau ggaccgaucg uagaaggagu uaccguuaaa ggagacuuaa     2820

acggcucaga ugacgcagau acuuuuuacu ucgaugucaa agaagacgga gaugucacaa     2880

uagaauuacc cuacagugga ucuucaaacu uuaccuggcu agucuauaaa gaaggagaug     2940

accaaaauca uauagcaagc ggaauagaua aaaacaacag caaaguaggc acauucaaaa     3000

guacaaaagg caggcauuac guauuuauau acaaacacga uucugccuca aacauuucuu     3060

acaguuuaaa uauuaaaggu cuaggaaaug aaaaacuaaa agaaaaagaa aacaacgacu     3120

caucugacaa agcaacagua auaccuaacu ucaacacaac aaugcaagga ucauuacuag     3180

gagaugacag uagagauuac uauucauuug aaguaaaaga agaaggugaa guaaauaucg     3240

agcuagauaa gaaagacgaa uuuggaguga cauggacccu ucacccagaa ucaaauauaa     3300

acgaucgaau aacauaugga caagucgaug gcaacaaagu aucaaauaaa guuaaauuaa     3360

gaccaggaaa auauuaucuc cuuguauaca aguauucagg caguggaaac uaugaauuga     3420

gaguaaacaa augaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  4828
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt12)

<400>  4828
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguca cauuuauuuc acuacuguuu uuauucucau      120

cagcauauag uauagcaaau acaaacagug aaaaauacga uuucgaauau cucaacggau      180

ugucauauac agaacuuacc aaccuuauua aaaauauaaa auggaaccaa auaaaugguc      240

uauuuaauua caguacgggu ucgcagaaau ucuuuggaga uaaaaaccgu guacaggcca      300

uaauaaacgc acuacaggaa uccggacgca ccuauacggc uaaugauaug aaaggaauag      360

aaacuuuuac ugaaguacua agagccggau uuuaucucgg auauuacaau gauggauuga      420

guuaccuaaa cgauaggaac uuucaagaca aauguauucc agcaaugaua gcaauacaga      480

aaaaccccaa cuucaaauua ggcacagccg uacaagacga aguuauaacu ucauuaggaa      540

aauuaaucgg uaacgcaagc gcaaacgccg aaguaguaaa uaauugugua ccaguacuaa      600

aacaauucag agaaaaccuc aaccaauacg cacccgauua cguaaaaggg acagcaguaa      660

augaauuaau aaaagguauc gaauuugacu ucuccggagc agcuuaugaa aaagacguua      720

aaacuaugcc cugguacgga aaaauagauc cuuuuauaaa ugaacucaaa gcauuaggac      780

ucuaugggaa uauaacaucg gcuacugaau gggccagcga cguaggaaua uauuauuuau      840

caaaauuugg gcuauacuca acgaacagga augauauagu acaaucgcua gaaaaagccg      900

uagacaugua uaaauauggu aaaauugcau ucgucgcaau ggaaagaauu acaugggauu      960

augacggaau aggguccaac ggcaagaaag uagaucacga uaaauuuuua gacgacgcug     1020

aaaaacauua uuuaccaaaa acauauacuu uugacaacgg uacauucauc auuagggcag     1080

gagauaaagu uuccgaagag aaaauaaaaa gauuauacug ggcaagucga gaaguaaaau     1140

cacaauucca cagaguagua ggcaacgaua aagccuuaga agucgguaau gcugacgaug     1200

uauuaaccau gaaaauauuc aacaguccug aagaauacaa auuuaauacc aauauaaaug     1260

gaguaaguac cgauaauggc ggacuauaca uagaaccucg aggaaccuuc uacacguacg     1320

aacgaacucc gcaacaauca auauuuaguc uagaagaacu auuucggcau gaauauacgc     1380

acuacuuaca agcuagauau cuuguagacg gauuaugggg gcaaggaccc uucuaugaaa     1440

agaaucgauu aacaugguuu gacgaaggaa cugcugaauu uuucgcaggu ucaacaagaa     1500

cgucaggagu acuaccaagg aaaaguauac uaggcuaccu ugcaaaagau aaaguugauc     1560

aucgauauuc acuaaagaaa acacuaaaua gugguuauga cgacucagau uggauguucu     1620

auaacuaugg uuuugcagug gcacauuauc uauaugaaaa agauaugcca accuucauaa     1680

aaaugaacaa agccauauua aauacugacg ucaaaucaua cgacgaaaua auuaagaaau     1740

uaucagacga ugcaaacaaa aauacagaau aucaaaacca uauacaagaa uuagcagaua     1800

aauaucaagg ugcagguauu ccauuaguau cggaugauua uuuaaaagau cauggauaca     1860

agaaagccag cgaaguauac ucugaaauua gcaaagcagc gucacucacg aauacaucug     1920

uuacugcaga aaaaucacaa uauuuuaaua cauuuacacu gcguggaacc uauaccggag     1980

aaacaucaaa aggugaauuu aaagacuggg acgaaauguc aaagaaacua gauggaaccc     2040

ucgaaaguuu agccaaaaau ucauggagug gauauaaaac ucuuacugca uacuucacua     2100

auuacagagu aacaucagac aacaaaguac aauacgacgu aguauuucau ggcgucuuga     2160

cagauaaugc cgacauuuca aauaacaaag ccccaauagc uaaagugaca ggaccaucaa     2220

caggcgcagu cggaagaaau auugaguucu cagggaaaga uaguaaagac gaagauggaa     2280

aaauaguuag cuaugacugg gacuucggag auggagcaac aucucgaggu aaaaacuccg     2340

uacacgcaua uaagaaagcu ggaaccuaua acguuacauu aaaaguaacu gaugauaaag     2400

gagcaacugc aacagaaagu uuuacuauag aaaucaaaaa cgaagauacc acaacaccaa     2460

uaacaaaaga aauggaacca aacgacgaca uaaaagaagc gaauggaccc auaguagaag     2520

gagucacugu uaaaggagac uuaaauggga gcgacgaugc cgacacuuuu uauuucgacg     2580

uuaaagaaga uggagacgua acuauagaau uacccuacuc uggaaguagu aauuuuaccu     2640

ggcuaguaua caaagaaggc gaugaucaaa accauauagc gucaggaaua gauaaaaaua     2700

auucaaaagu gggcacuuuc aaaagcacaa aaggaagaca uuacguauuc auuuauaaac     2760

acgauucagc aucaaacaua ucauacucgc uuaauauaaa aggacuagga aacgaaaaac     2820

uuaaagaaaa agaaaacaau gacucaucag acaaagccac aguaauucca aauuuuaaca     2880

cuacuaugca aggaagccuu uuaggagaug auaguagaga uuauuauuca uucgaaguaa     2940

aagaagaagg agaaguuaau aucgaacuag auaagaaaga ugaguucggu guaacgugga     3000

cauuacaccc ugaauccaau auuaacgaca gaaucaccua uggacaaguu gacggaaaua     3060

aagucagcaa caaaguuaaa uuaagacccg gaaaauauua ccuccuaguu uauaaauaua     3120

gcggaucagg aaacuacgaa uuacgaguaa auaaaugagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  4829
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt12)

<400>  4829
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguaa cauucauauc auuacuuuuc cuauuuucau      120

cagcauacag uaugaagaaa aauauauuaa aaauauuaau ggacagcuau agcaaagaau      180

caaaaauaca aacaguuaga agaguaacua gcguuagcuu auuagccgua uacuuaacaa      240

ugaauacaag uagccuagua uuagcaaaac cgauagaaaa uacaaacgac acgagcauca      300

aaaacguuga aaaacuaaga aaugccccca acgaagaaaa caguaagaaa gucgaagaca      360

guaaaaauga uaaaguagaa caugugaaaa acauagaaga agccaaagua gaacaaguag      420

ccccugaagu uaaaagcaaa ucaacgcuac gcagcgccag uaggagaaga agaaaaagaa      480

uagcaaauac uaacucagaa aaauaugacu ucgaauacuu aaauggacua aguuacacag      540

aacuuaccaa ucuuaucaaa aacauaaaau ggaaucaaau aaauggacua uucaauuauu      600

ccacuggguc acaaaaauuu uucggagaua aaaauagagu gcaggcuaua auuaacgcac      660

uacaagaauc aggaagaacc uacacagcaa acgauaugaa agggauagaa acuuucacug      720

aaguacugcg agcgggauuc uauuuggggu acuauaacga cgguuuauca uacuuaaacg      780

acagaaauuu ucaagacaaa uguauaccag caaugauagc aauacagaaa aauccuaauu      840

uuaaacuagg gaccgcagua caagacgaag ugauaacauc acucgguaaa cucauaggaa      900

augcuucagc uaaugcggaa guaguaaaua auugcguacc aguuuuaaaa caauucagag      960

aaaaccucaa ccaauaugca cccgacuaug uaaaaggaac ugcaguuaac gaacuuauca     1020

aaggaaucga auuugauuuu agcggagccg cguacgaaaa agacgugaaa acaaugccuu     1080

gguauggaaa aauagaccca uucauuaacg aauuaaaagc cuuaggccug uacgguaaua     1140

uaacuucagc cacagaaugg gcaagugacg uuggcauaua cuauuugucg aaauuuggau     1200

uguauucaac aaaccguaac gacauaguuc aaagccugga aaaagcagua gauauguaca     1260

aauauggaaa aauagccuuu guagcaaugg aaaggauuac augggauuau gacggaauag     1320

gcucaaaugg uaagaaagua gaucaugaua aguuucuaga cgaugcagaa aaacacuauc     1380

uuccaaagac auacaccuuc gacaauggaa cuuuuauuau aagggcaggc gacaaaguau     1440

ccgaagagaa aauaaaacgu uuauacuggg caucacggga aguaaaaagc caauuucaua     1500

gaguaguagg aaacgacaaa gcauuagaag uaggaaacgc agaugacgua cucacaauga     1560

aaauauucaa uucuccugaa gaauauaaau ucaauacaaa uauaaaugga gucaguacag     1620

acaauggagg acuauacaua gaaccuagag ggacauuuua uacuuacgaa agaacacccc     1680

aacaauccau auuuucccua gaagaauugu uccgacauga auacacacau uauuuacaag     1740

cccgauacuu aguagacgga uuauggggac aagguccauu cuacgagaaa aacagauuga     1800

caugguucga cgaaggaaca gcagaauuuu ucgccggauc aacuagaacc uccgguguau     1860

uaccaagaaa auccauccuu ggguacuuag caaaagauaa aguagaucau cguuauucgu     1920

uaaagaaaac auuaaauagc ggcuacgaug auucagauug gauguuuuau aauuauggcu     1980

uugcuguagc acauuaucua uacgaaaaag auaugccaac uuucaucaaa augaacaaag     2040

cgaucuuaaa uacagacguu aaaucauaug acgaaaucau aaagaaauua ucagaugaug     2100

caaauaaaaa cacagaauau caaaaccaca uacaagaacu agcugauaaa uaucagggug     2160

caggaauccc acucguaucg gacgauuacc uaaaagacca uggauauaag aaagcaagcg     2220

aaguauacuc agaaauuagu aaagcugcau cucuuacaaa uacaagcgua acggcagaga     2280

aaagccaaua uuucaacacg uucacacuac gcggaacaua uacuggagaa acaaguaaag     2340

gagaguucaa agauugggac gaaaugucaa agaaauuaga ugguacuuua gaaucauuag     2400

ccaaaaauag cugguccggg uacaaaacac uuaccgcaua cuuuacaaau uauagaguca     2460

caagcgauaa uaaaguucaa uacgaugucg ucuuucacgg aguacuaaca gacaacgcgg     2520

auauaagcaa uaauaaagca ccaauagcaa aaguaacagg accaucaacc ggagcuguug     2580

gaagaaacau ugaguucuca ggaaaagacu caaaagacga agauggcaaa auaguaagcu     2640

augauuggga uuuuggagac ggcgcaacau ccagaggcaa aaauagcguc caugccuaua     2700

agaaagcagg aacauacaac guaacauuaa aaguaacaga cgacaaagga gccaccgcca     2760

cugaaaguuu uacuaucgaa aucaaaaaug aagauacaac caccccaaua accaaagaaa     2820

uggaaccuaa ugaugacaua aaagaagcua augggccaau uguagaagga gucacaguca     2880

aaggcgacuu aaacgggagc gacgacgcug auaccuucua cuuugacgua aaagaagaug     2940

gagauguaac aauagaacua ccauauucag guucauccaa uuuuacaugg cuaguguaca     3000

aagaagguga cgaccaaaac cauauagcca guggaauuga caaaaacaau ucuaaagugg     3060

ggacuuuuaa aagcacaaaa gguagacauu auguauuuau auacaaacau gauagugcaa     3120

gcaacauauc auacucucua aauaucaaag gcuuaggaaa cgaaaagcua aaggaaaagg     3180

aaaauaacga uuccucagau aaagcaacug ugaucccaaa uuucaacacu acuaugcaag     3240

gcagccuucu cggugaugau agccgagauu acuacuccuu ugaagucaaa gaagaaggug     3300

aagucaacau agaauuggau aagaaagaug aguucggcgu cacauggaca cugcauccag     3360

aaucaaacau aaacgauaga aucaccuacg gacaagucga cggaaauaaa guaagcaaua     3420

aagucaaauu aagaccagga aaauacuacc uucuaguaua uaaauacucu ggaaguggaa     3480

auuacgaauu acgaguuaau aaauaaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  4830
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt12)

<400>  4830
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuuuuga agauaauacu aaauagagga aaaacaauga      120

aaagaaaaug ccuauccaaa cgauuaaugc uggccauaac uauggcaaca auauuuacag      180

uaaacaguac auuaccuaua uaugcagcug uagauaaaaa caacgcuaca gcugccgucc      240

agaacgaauc uaaaagguac accguaucuu aucuaaaaac ucuaaacuac uaugacuuag      300

uagauuugcu aguaaaaaca gaaauagaga aucuaccaga cuuauuucaa uauucaagcg      360

augccaaaga guucuaugga aauaaaacca gaaugaguuu uauaauggau gaaauaggua      420

gacgagcacc acaauacaca gaaaucgacc auaagggaau accgacacuu guagaagugg      480

uaagagcagg auucuauuua ggauuccaua auaaagaauu aaacgagaua aacaaacgau      540

ccuuuaaaga aagagucaua ccaagcauau uagcaaucca gaaaaaucca aauuucaagc      600

uaggaacaga aguacaagau aaaauuguaa gcgcaacagg auuacucgca gggaacgaaa      660

cagcaccccc agaagucgug aacaacuuca ccccaauacu ccaagacugu aucaaaaaua      720

uagauagaua cgcacuagau gaccuaaaaa guaaagcccu uuucaacgua cuugcagcac      780

caaccuauga uauaacugaa uaccuacgag caacaaaaga gaaaccagaa aacacacccu      840

gguacgggaa aauagacggc uuuauaaaug aguuaaagaa auuagccuua uaugguaaaa      900

uaaaugauaa uaauucaugg auaauagaca acggcauuua ucauaucgca ccucugggaa      960

aauuacacag uaauaacaaa auagguauug aaacacuaac agaaguaaug aaaguuuauc     1020

cauaucuaag caugcaacac cuccaaucag cagaucaaau aaaacgacac uacgacucua     1080

aggacgcaga agggaacaaa auaccacuag acaaauucaa gaaagaagga aaagaaaaau     1140

acugcccaaa aacauauaca uucgacgaug gcaaaguaau uaucaaagcu ggcgcaaggg     1200

uagaggaaga aaaaguaaaa cgucuauauu gggcuucaaa agaaguaaau ucacaauucu     1260

uucgaguuua cggaauugau aaaccauuag aagaaggaaa cccagaugac auucuaacua     1320

ugguuauaua uaauucacca gaagaauaua aacuaaacuc aguauuauac ggauaugaua     1380

ccaacaacgg ugggauguac auagaacccg aaggaacauu cuuuacuuau gaacgcgaag     1440

cacaagaaag cacuuacacg uuagaagaac uauuccgaca cgaauauaca cauuacuuac     1500

aaggacgcua ugcaguucca ggacaauggg gacgaacaaa auuauaugau aacgacagac     1560

uaacauggua cgaagaagga ggagcagaau uauuugcugg uaguacucga acaaguggaa     1620

uacuacccag aaaaagcauu guaagcaaca uacauaauac aacacgcaac aacagauaua     1680

aacuaucaga uacuguacau uccaaauaug gcgccagcuu ugaguucuac aacuacgcau     1740

gcauguucau ggacuacaug uacaauaaag acauggguau acucaacaaa cuaaacgauc     1800

ucgccaaaaa uaacgacguu gacggauaug auaauuacau uagagaccuc aguucaaauu     1860

augcauuaaa ugacaaauac caagaucaca ugcaagaaag aauagauaac uaugaaaacu     1920

uaacaguacc auucguugca gacgauuacu uaguaagaca cgcauauaaa aacccuaacg     1980

aaauauauuc ggaaauuuca gaaguugcaa aauuaaaaga ugcaaaaucu gaaguaaaga     2040

aaagucaaua uuuuucgacc uucacauuac guggaagcua uacaggaggu gcauccaaag     2100

gaaaacucga agaucaaaaa gcaaugaaca aauuuauaga cgacucuuua aagaaacuag     2160

acacauauuc guggagcggg uacaaaacau uaacggcaua cuucacgaau uauaaaguug     2220

acaguucaaa uagagucaca uaugauguag ucuuucacgg auaccuaccu aacgaaggag     2280

acaguaaaaa uagucucccc uaugggaaaa uaaauggcac auacaaaggu accgagaaag     2340

agaaaauaaa auuuuccucg gaaggcucau ucgacccuga uggaaaaaua guaucauacg     2400

aaugggacuu cggagaugga aauaaaagua acgaagaaaa uccagaacac ucauacgaua     2460

aaguagggac cuauaccgua aaacucaaag uaacagauga caaaggcgaa agcucaguuu     2520

caacaacaac ugcagaaauu aaagauuuau cagaaaauaa auuaccagua auauauaugc     2580

auguaccaaa aaguggggca cuaaaucaaa aaguaguguu cuaugggaaa ggaacauaug     2640

auccagacgg aucaauugca gguuaccaau gggauuuugg agaugguuca gauuucucaa     2700

gugaacaaaa uccaucccac guuuauacaa agaaaggaga auacacagua acuuuacgag     2760

uaauggacag uucagggcaa augucggaga aaacaaugaa aauuaaaaua acagauccag     2820

uauacccaau aggaacagaa aaagaaccua auaauucaaa agaaacugca ucagggccaa     2880

uaguacccgg aauacccgua uccgguacua uagaaaacac aucagaucaa gacuacuucu     2940

auuuugaugu uauaacgcca ggagaaguaa aaauagauau caacaagcua ggauauggag     3000

gagcaacgug gguaguguau gaugaaaaua auaacgcagu uucauaugca acugacgaug     3060

gacaaaaccu cuccggaaaa uucaaagcag auaaaccagg aagguauuac auacaccugu     3120

acauguucaa uggcucuuau augccguauc guauaaauau cgaaggguca guaggaagau     3180

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  4831
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt12)

<400>  4831
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacgaaaau gcuuaucaaa aagauuaaug uuagcaauaa      120

caauggccac uauauucacu gucaauucaa cccuuccaau auacgccgca guagacaaga      180

acaaugcuac agcagcagua caaaaugaaa guaagagaua cacaguaucg uaucuaaaaa      240

cucuaaacua uuaugaccuc guggaccugc uaguaaaaac agaaauagaa aauuuaccug      300

auuuauucca guauucauca gaugcaaaag aguucuaugg caauaagaca agaauguccu      360

ucauaaugga ugaaauaggc agacgagcac cacaauacac ugaaauugac cacaagggaa      420

uaccaacccu agucgaagua gucagagcag gauucuaccu aggcuuccau aauaaggaac      480

uaaacgaaau aaacaaaaga aguuucaaag aaagagugau accaucaaua uuagcaauac      540

agaaaaaucc caacuuuaaa cuuggaacag aaguacaaga caaaauugug agcgcaaccg      600

gauuacuagc agggaacgaa acagcaccuc ccgaaguagu gaauaauuuu acgccaauau      660

uacaagauug cauuaaaaac auagacagau augcacuaga ugauuuaaaa ucuaaagcau      720

uauuuaacgu acuagcagcu cccacauaug auauaacaga auaccucaga gccaccaaag      780

aaaaaccuga aaauacacca ugguauggaa aaaucgacgg cuuuaucaau gaacuuaaaa      840

agcuagcacu auauggaaaa aucaacgaua acaacucaug gaucauagau aauggaauau      900

accauauagc acccuuaggc aaacuucacu caaacaauaa aaucggcaua gaaacauuaa      960

cggaaguaau gaaaguauac ccuuaucuau cuaugcaaca uuuacaauca gcagaucaaa     1020

uaaaacgcca cuacgauagu aaagaugcag aaggaaacaa aauaccccuc gacaaguuca     1080

agaaagaagg aaaagaaaaa uauuguccaa aaacauauac guucgacgau ggaaaaguaa     1140

uaauaaaagc aggagcaaga guagaagagg aaaaaguaaa aagauuauac ugggcgucaa     1200

aagaaguaaa cucacaauuc uucagaguuu auggaauaga caaaccauua gaggaaggaa     1260

aucccgauga cauucuuacc auggugaucu acaacagucc ugaagaauau aaacuaaauu     1320

cuguccucua cggauaugau acaaacaacg gaggcaugua uaucgaacca gaaggaaccu     1380

uuuucacaua ugagagagaa gcucaagaau caaccuacac ccucgaggaa cuauucagac     1440

acgaauauac gcacuaucua caaggcaggu acgcaguacc cggacaaugg ggccguacaa     1500

aacuauauga caacgacaga cuaacuuggu acgaagaagg aggggcugaa uuauuugccg     1560

gaucaacaag aaccucaggg auucuuccac gaaaaucgau aguuucgaau auacacaaua     1620

caaccagaaa caauagauau aaauuaucag auacagugca uuccaaauau ggggcuucau     1680

ucgaguuuua caauuaugcu ugcauguuca uggauuauau guauaacaaa gacaugggaa     1740

uacucaacaa acuaaaugac cucgcuaaaa acaaugacgu agauggauac gacaauuaca     1800

uacgcgauuu aagcuccaac uaugcauuaa acgacaaaua ucaagaucau augcaagaaa     1860

gaauagauaa uuaugagaau cuaacaguac cguucgucgc agaugauuac uuagugcggc     1920

acgcauauaa aaacccuaau gaaauuuaua gcgaaauaag ugaaguugca aaauuaaaag     1980

acgcaaaaag ugaaguaaag aaaucacaau acuuuagcac auucacauua agaggaaguu     2040

auacuggagg agccuccaaa gguaaacuag aagaccaaaa agcuaugaac aaauuuauag     2100

augauagucu uaagaaacuu gacaccuauu cauggagugg auauaaaaca uuaacagcuu     2160

auuucacuaa cuauaaagua gauucaucaa aucgcguaac uuaugauguc guuuuccacg     2220

guuauuuacc caacgaagga gacaguaaaa acucacuacc auacgguaaa auaaauggca     2280

cuuacaaagg aacagaaaaa gagaaaauaa aauucaguuc ugaaggauca uucgacccag     2340

auggaaaaau agugagcuau gaaugggacu ucggagaugg uaauaaaagc aaugaagaaa     2400

auccagaaca caguuaugac aaaguaggua cauacacugu uaaauuaaaa gucacagacg     2460

auaaaggcga aaguucagua ucaacaacaa cagccgaaau aaaagaucua agcgaaaaca     2520

aacuacccgu cauauauaug cacguaccua aaaguggagc ccuuaaccaa aaagugguau     2580

ucuacggaaa aggaacauac gacccugacg gaagcauagc aggauaucaa ugggacuucg     2640

gugacgguuc ggacuucucu ucugaacaaa auccaagcca cguauacaca aagaaaggag     2700

aauacaccgu aacacuuaga guuauggaca gcucaggaca aaugucagag aaaacaauga     2760

aaaucaaaau uaccgacccu guauauccaa uaggaacuga aaaagaacca aauaacagua     2820

aagaaacagc uaguggaccg aucguuccag guauuccugu aaguggaaca aucgaaaaca     2880

caucagacca ggacuauuuu uauuucgaug uaauaacacc aggagaaguc aaaaucgaua     2940

uaaauaaacu aggauaugga ggggcuacau ggguaguaua cgaugaaaac aacaaugcag     3000

uauccuacgc gacagaugac ggacagaacc uuucaggaaa auucaaagcg gacaaaccag     3060

gcagguacua cauacaccua uacauguuca acggauccua uaugccuuau cgaauuaaua     3120

uagaaggauc cguaggccgu uaaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  4832
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt12)

<400>  4832
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguga cauucauauc ucuacuuuuc cuauucuccu      120

cagcauacuc aguacaaaac gaaucaaaaa gauacacagu gaguuacuua aaaacguuaa      180

acuacuauga ccuaguagac cuucuaguaa aaaccgaaau agaaaaucua ccagaccuau      240

uccaauacuc uucagaugcc aaagaauuuu auggaaauaa aaccagaaug aguuucauca      300

uggaugaaau cggaaggaga gcaccacaau acacggaaau agaucacaaa gguauaccca      360

cuuuaguaga agucguaaga gcaggauucu acuuaggauu ccauaacaaa gaacucaaug      420

aaauuaauaa aagaucuuuc aaagaaaggg uaauacccag cauacucgcc auacagaaaa      480

accccaacuu caaacuagga acagaaguac aagauaaaau aguaucagca acugguuuac      540

ucgcuggaaa ugaaaccgca ccaccagaag uaguaaacaa cuucaccccu auucuacaag      600

acugcauuaa aaauauagac agauacgccc uagacgacuu aaaaucgaag gcccucuuua      660

acguacuagc cgccccaaca uaugauauaa cagaauacuu aagagcaacc aaagaaaaac      720

cagaaaauac acccugguac ggaaaaauag acggauuuau aaaugaauua aagaaauuag      780

cguuauaugg gaaaauaaac gacaauaaua guuggauaau agacaacgga auauaccaca      840

uagcaccauu aggcaaacua cacuccaaua acaaaauagg gauagaaacc uuaacagaag      900

uaaugaaagu auauccauau cuaucaaugc aacauuugca aucagcagac caaauaaaac      960

gacauuauga uaguaaagac gcagaaggaa auaaaauacc acuagauaaa uucaagaaag     1020

aaggaaaaga aaaauauugu ccaaaaacau acacauucga ugacggaaaa guaauaauua     1080

aagccggugc ccggguagaa gaagaaaaag uaaaacgacu guauugggcu ucuaaagaag     1140

ucaauucaca auucuuuagg guauacggaa uugauaaacc ucuagaagaa gguaacccag     1200

acgacauccu aacaaugguc auauacaaua gcccggaaga auacaaauua aacucgguau     1260

uauacgggua ugacacaaau aacggcggca uguacauuga acccgaagga acguucuuca     1320

cauaugaaag agaagcacaa gaaucaacau acacacucga agaacuauuu agacacgaau     1380

auacacauua uuuacaaggg agauacgccg uacccggaca auggggucga accaaacuuu     1440

acgacaacga caggcuaaca ugguacgaag aagggggagc agaauuauuc gcaggaucaa     1500

caagaaccuc aggaauacua ccuagaaaaa guauaguauc aaauauacau aauacaacca     1560

ggaauaacag auauaaauua agugacacag uccauucaaa auauggagcc uccuuugagu     1620

ucuauaacua cgcauguaug uucauggauu acauguacaa caaagauaug ggaauccuaa     1680

acaaacuaaa cgaccuagcu aaaaauaacg auguugacgg auacgauaac uacauaagag     1740

accucagcuc aaacuaugca cuuaacgaca aauaucaaga ucauaugcaa gaaagaauag     1800

acaacuacga aaaucucaca guaccauucg uagcagacga uuauuuagua agacacgcau     1860

acaagaaccc uaacgaaauc uauuccgaaa uuagcgaagu agcgaaacuu aaagacgcaa     1920

aaagugaagu aaagaaaagu caauacuuca gcacauucac acuacgagga uccuacacag     1980

gcggcgcaag caaaggcaaa cuagaagauc aaaaagcaau gaacaaauuc auagacgauu     2040

cacucaagaa auuagauaca uauagcugga guggauacaa aacacuaacu gcauauuuca     2100

caaacuacaa aguugacagc ucaaauagag ucacauauga uguaguauuc cacggauauc     2160

uacccaauga aggugacagc aaaaacuccu uaccauacgg aaaaauuaac gggacauaca     2220

aaggaacaga aaaagagaaa auaaaauucu cauccgaagg uagcuuugac cccgauggaa     2280

aaauuguauc auaugaaugg gacuucggag acggaaauaa aucaaacgaa gaaaauccug     2340

aacacagcua ugauaaaguu ggcaccuaua ccgugaaacu aaaagugaca gaugacaaag     2400

gugaaucauc cguauccaca acgacagcag aaauuaaaga cuuaagcgaa aacaaacuac     2460

caguaauaua caugcaugua ccaaaauccg gcgcauuaaa ucaaaaaguc guauuuuaug     2520

gaaaagggac uuaugacccc gaugggucaa ucgcaggcua ucaaugggac uucggcgaug     2580

gcucagacuu cucaucagaa cagaacccau cucauguuua cacaaagaaa ggagaauaca     2640

caguaacauu acgagucaug gauucaucag gucaaauguc agagaaaaca augaaaauaa     2700

aaauaacaga uccgguuuac ccaauaggaa cagaaaaaga acccaacaau ucaaaagaaa     2760

cagcaagugg cccuauaguu ccagguauuc cuguaucagg uacaaucgaa aacacaucag     2820

accaggauua cuuuuacuuc gacgugauua cgccaggaga aguuaaaauc gauauuaaua     2880

aauuaggaua ugguggagcc acguggguag uauacgauga aaauaauaau gcaguaucau     2940

augccacaga ugacggacaa aaucuuucag ggaaauuuaa agcugauaaa ccaggaagau     3000

auuauauaca ccuuuacaug uucaacgguu cauacaugcc uuacagaaua aauauagaag     3060

gauccguagg uagauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4833
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt12)

<400>  4833
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguga cauucaucuc acuauuauuu cuauucagua      120

gcgcauauuc uaugaaacga aaaugcuuau ccaaaagacu aaugcuagca auaacaaugg      180

caacaaucuu caccguaaau ucaacauuac caaucuacgc agccguagau aaaaacaaug      240

caacagcagc ucgaaggaga aggaaaaggg uacaaaacga aagcaaaaga uauaccguca      300

gcuaccuuaa aaccuuaaau uacuacgacu uaguagaucu cuuaguaaaa acagaaauag      360

aaaacuuacc cgauuuguuu caauauucau ccgacgcaaa agaguucuac ggaaauaaaa      420

caagaaugag cuucauaaug gacgaaauag gucggagagc uccccaauau accgaaauag      480

aucauaaagg aauaccaacc uuaguagaag uaguaagagc cggauuuuac cuuggcuucc      540

auaacaaaga acuaaacgaa auaaacaaac gauccuucaa agagcgcgua auaccaagua      600

uacuggccau ccagaaaaac ccaaacuuua aauuaggaac ggaaguucaa gacaaaauag      660

uaagugcaac agggcuccua gcaggaaacg aaacagcucc cccugaaguu guaaauaacu      720

ucacaccaau acuucaagac uguauuaaaa acauagacag auacgcauua gacgaccuua      780

aaagcaaagc guuauuuaac guacuagcug cacccacuua ugacauaacu gaauacuuaa      840

gagcaacaaa agaaaaacca gaaaacacac cuugguaugg caaaauagau ggauuuauaa      900

augaacuaaa gaaacuggca cuauauggca aaaucaacga uaauaacagu uggauaauag      960

acaacgguau auaucauaua gcaccacuag guaaauugca uucaaacaau aaaauuggua     1020

uagaaacguu aacagaggug augaaaguau acccauaccu aucuaugcaa cauuuacaau     1080

cagcggauca aauuaaaagg cacuaugauu caaaagaugc ggaagguaac aaaauaccac     1140

uagacaaauu caagaaagaa ggaaaagaaa aauauugucc caaaacauac acauuugaug     1200

augguaaagu aauaauaaaa gcaggggcuc gaguagaaga agaaaaaguu aaacgacuau     1260

acugggccuc aaaagaaguc aacucucaau uuuuccgcgu auacggaauc gauaaaccau     1320

uagaagaagg uaauccggau gauauauuaa ccauggugau cuacaacuca ccagaagaau     1380

acaaacuaaa uucaguccua uauggauacg acacuaauaa ugguggaaug uacauagaac     1440

cagaaggcac auucuucaca uacgaaagag aggcucaaga aucaacauac acacuagaag     1500

aauuauuccg acacgaauac acacauuacu uacaaggaag auacgcggua cccggacaau     1560

ggggaagaac aaaacuauac gauaaugauc gacuuacaug guaugaagaa ggaggagccg     1620

aacuauucgc aggauccacg cgcaccucag ggauucuucc aagaaaauca auaguaucaa     1680

auauacacaa uacaacacga aauaacagau auaaauuauc agacacagua cacuccaaau     1740

auggcgcaag uuucgaguuc uacaauuacg cauguauguu cauggauuac auguauaaca     1800

aagauauggg gaucuuaaac aaacuaaacg auuuagcgaa aaacaaugac guagacggcu     1860

augacaacua cauacgagac uuauccagca auuacgcacu uaacgauaaa uaccaagauc     1920

acaugcaaga aagaauagau aacuacgaaa aucuaacagu cccauuuguc gcagacgacu     1980

accuggugag acacgcuuac aaaaauccaa augaaauaua cucagaaaua agcgaaguag     2040

cuaaacucaa agacgccaaa agugaaguua agaaaaguca auacuuuuca acauucaccc     2100

uccggggauc auauaccggg ggagcaucua aaggaaaauu agaagaccaa aaagccauga     2160

auaaauuuau agaugacucc cuaaagaaac uggacacuua cuccuggagu ggguacaaaa     2220

cuuuaacagc uuauuucacc aacuauaaag uagacagcag caaucgaguc acauaugacg     2280

ucguguuuca ugguuacuua ccaaacgaag gagacagcaa aaacucacuu cccuauggua     2340

aaauaaacgg uacauacaaa ggaacagaaa aagagaaaau uaaauucucu ucugaaggau     2400

cauuugaucc agauggaaaa aucgugaguu augaauggga cuuuggagac ggaaacaaau     2460

cuaacgaaga aaacccagaa cacaguuaug auaaaguugg aaccuacaca guaaaacuaa     2520

aagugacuga cgauaaagga gaaucaucag ucaguacaac uacagccgaa auaaaagauc     2580

uaagcgaaaa uaaacucccc guaauauaua ugcacguccc aaaaucagga gccuuaaauc     2640

aaaaaguugu cuuuuacggu aaaggaacau acgaucccga uggaucaauc gcaggauauc     2700

aaugggacuu uggagauggu agcgauuucu ccagcgaaca aaaccccuca cacguauaua     2760

caaagaaagg agaguauaca guaacauuaa gagugaugga uagcucggga caaaugucag     2820

agaaaacaau gaaaauaaaa auuacggauc caguauaccc cauaggaaca gaaaaagaac     2880

caaacaauuc caaagaaacc gcuagugguc caaucguacc cggcauuccg gugagcggua     2940

cuauagagaa cacaucagac caagauuacu uuuacuucga cgucauuaca ccaggcgaag     3000

uaaaaauaga uauaaauaaa uuagguuacg gaggugcaac uuggguagua uaugacgaga     3060

acaacaacgc cgucucauac gcaaccgacg acggucaaaa ucuaucagga aaauucaaag     3120

cagacaaacc agguagauac uacauucacc uauacauguu caauggaagu uacaugccau     3180

acagaauaaa cauagaagga uccguuggaa gauaaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  4834
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt12)

<400>  4834
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuuuucgc augccuacuc ggagcagcau      120

ucgcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc auacccauca uacggauacg      240

aaccaauggg aggaugguua caccaccaaa uaauaccagu acuaucacaa caacacccac      300

ccacacacac auuacaacca caccaccaca uaccaguagu accagcacaa caaccaguaa      360

uaccacaaca accaaugaug ccaguaccag gacaacacuc caugacacca auacaacacc      420

accaaccaaa ccuaccacca ccagcacaac aaccauacca accccaacca guacaaccac      480

aaccacacca accaaugcaa ccacaaccac caguacaccc aaugcaacca cuaccaccac      540

aaccaccacu accaccaaug uucccaaugc aaccacuacc accaaugcuc ccagaccuaa      600

cacuagaagc cuggccauca acagacaaaa caaaaagaga agaaguagac uaaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  4835
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt12)

<400>  4835
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccuc cacauccagg ucacccugga uauauaaauu      120

ucucuuacga aguacuuaca ccucuaaaau gguaucaauc uauacgucca ccuuacccuu      180

cauauggaua ugaaccuaug gguggauggu aaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  4836
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt12)

<400>  4836
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca ccaccaaugc      180

uaccagaccu aacacuagaa gcauggccau caacagacaa aacaaaaaga gaagaaguag      240

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  4837
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt12)

<400>  4837
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa ucaauaagac      240

caccauaccc aucauacgga uacgaaccaa ugggaggaug guaaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  4838
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt12)

<400>  4838
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa ucaauaagac      240

caccaccaau gcuaccagac cuaacacuag aagcauggcc aucaacagac aaaacaaaaa      300

gagaagaagu agacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  4839
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt12)

<400>  4839
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uccuauucgc uugccuagua ggagcagcau      120

ucgccaugcc auuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acucaaaugg uaccaaucaa ugauaagacc accauacuca ucauacggau      240

acgaaccaau gggaggaugg cuacaccacc aaauaauacc aguaguauca caacaacacc      300

cauuaacaca cacacuacaa ucacaccacc acauaccagu aguaccagca caacaaccaa      360

gaguaagaca acaagcacuc augccaguac ccggacaaca aucaaugaca ccaacacaac      420

accaccaacc caaccuacca cuaccagcac aacaaccauu ccaaccacaa ccaguccaac      480

cacaaccaca ccaaccaaug caaccacaac caccuguaca accaaugcaa ccacuauuac      540

cacaaccacc acucccaccc auguucccac uaagaccacu accaccaaua cuaccagacc      600

uacaccuaga agcauggcca gcaacagaca aaacaaaaca agaagaaguc gacuaaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  4840
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt12)

<400>  4840
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aaugauaaga ccaccauacu      180

caucauacgg auacgaacca augggaggau gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4841
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt12)

<400>  4841
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aaugauaaga ccaccaccaa      180

uacuaccaga ccuacaccua gaagcauggc cagcaacaga caaaacaaaa caagaagaag      240

uagacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4842
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt12)

<400>  4842
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaucca ggacacccag      180

gauauauaaa uuucucauac gaaguauuaa caccacuaaa augguaucaa ucaaugauaa      240

gaccaccaua cagcucauac ggauacgaac caaugggagg augguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4843
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt12)

<400>  4843
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaucaa ucaaugauaa      240

gaccaccacc aauacuacca gaccuacacc uagaagcaug gccagcaaca gacaaaacaa      300

aacaagaaga aguagacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4844
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt12)

<400>  4844
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaccugga uauuauucgc augccuacua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc uccuacgaag      180

uauuaacacc acuaaaaugg uaccaaaaca ugauaagaca ccccuacaca ucauacggau      240

acgaaccaau gggaggaugg cuacaccacc aaauaauacc cguaguauca caacaaacac      300

cacaaucaca cgcacuacaa ccccaccacc acauaccaau gguaccagca caacaaccag      360

gaauaccaca acaaccaaug augccacuac caggacaaca cucaaugaca ccaacacaac      420

accaucaacc aaaccuacca cuaccagcac aacaaccauu ccaaccacaa ccaguacaac      480

cacaaccaca ccaaccacua caaccccaau caccaaugca ccccauacaa ccacuacuac      540

cacaaccacc acuaccacca auguucucaa ugcaaucacu acuacccgac cuaccacuag      600

aagcauggcc agcaacagac aaaacaaaac gcgaagaagu agacuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4845
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt12)

<400>  4845
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa uaugauaaga cacccauaca      180

caucauacgg auacgaacca augggaggau gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4846
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt12)

<400>  4846
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa caugauaaga cacccaucac      180

uacuaccaga ccuaccacua gaagcauggc cagcaacaga caaaacaaaa agagaagaag      240

uagacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4847
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt12)

<400>  4847
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaucca ggacacccag      180

gauauauaaa uuucucauac gaaguauuaa caccacuaaa augguaucaa aauaugauaa      240

gacauccaua uacaucauac ggauacgaac caaugggagg augguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4848
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt12)

<400>  4848
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa aacaugauaa      240

gacacccauc acuacuacca gaccuaccac uagaagcaug gccagcaaca gacaaaacaa      300

aaagagaaga aguagacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4849
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt12)

<400>  4849
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uauuauucgc augccuacua ggagcagccu      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacauaa      180

gacauccaua cacaucauac ggauaugaac caaugggagg auggcuacac caccaaauaa      240

uaccaguagu aucacaacaa accccacaau cacacgcacu acaaccacac caccacauac      300

caaugguacc agcacaacaa ccaggaauac cacaacaacc aaugaugcca uuaccaggac      360

aacacuccau gacaccaaca caacaccacc aaccaaaccu accacuacca gcacaacaac      420

cauuccaacc acaaccagua caaccacaac cacaccaacc acuacaacca caaucaccaa      480

ugcacccaau acaaccacua cuaccccaac caccacuacc accaauguuc ucaaugcaau      540

cacuacuacc agaccuacca cuagaagcau ggccagccac agacaaaaca aaacgagaag      600

aaguagacua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  4850
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt12)

<400>  4850
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uauucuucgc augcuuacua ggagcauccu      120

uagcaaugcc acuaccacca cacccaggcc acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaaaca ugauaagaca cccauacaca ucauacggcu      240

acgaaccaau gggcggcugg cuacaccacc aaauuauacc aguaguauca caacaaacac      300

cacaaucaca cgcacuacaa ccccaccacc acauaccaau gguaccagca caacaacccg      360

gaauaccaca acaaccaaug augccacucc caggacaaca cucaaugaca ccaacacaac      420

accaccaacc aaaccuccca cuaccagcac aacaaccauu ccaaccccaa ccaguacaac      480

cacaaccaca ccaaccacua caaccacaau caccuaugca cccaauacaa ccauuacuac      540

cccaaccacc acuaccacca auguucucaa ugcaaucacu acuaccagac cuaccacuag      600

aagcauggcc agcaacagac aaaacaaaaa gagaagaagu cgacuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4851
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt12)

<400>  4851
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaucaaaaca ugauaagaca cccaucacua uuaccagacc      240

uaccacuaga agcauggcca gcaacagaca aaacaaaaag agaagaagua gauuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  4852
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt12)

<400>  4852
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggcgcagcau      120

ucucaaugcc acuaccacca caccccggac acccaggcua cauaaacuuc ucauacgaag      180

auuuauacuu agaagcaaua agaauagaca gaacagcauu uguauuaaca ccacuaaaau      240

gguaccaaaa caugauaaga cacccauaca caucauaugg auacgaaccc augggaggau      300

ggcuacacca ccaaauaauc ccaguaguau cacaacaaac accacaauca cacgcccuac      360

aaccacacca ccacauacca augguaccag cacaacaacc aggaauacca caacaaccca      420

ugaugccacu accaggacaa cacucaauga caccaacaca acaccaccaa cccaaccuac      480

cacuaccagc acaacaacca uuccaaccac aaccaguaca accacaacca caccaaccau      540

uacaaccaca aucaccaaug cacccaauac aaccccuacu accacaacca ccacuaccac      600

caauguucuc aaugcaauca cuacuaccag accuaccacu agaagccugg ccagcaacag      660

acaaaacaaa aagagaagaa guagacuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  4853
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt12)

<400>  4853
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggagcagcau      120

ucucaaugcc acucccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaaaca ugauaagaca cccaacacca caaucacacg      240

cacuccaacc acaccaccac auaccaaugg uaccagcaca acaacccgga auaccacaac      300

aaccaaugau gccacuacca ggacaacacu ccaugacacc aacacaacac caccaaccaa      360

accucccacu accagcacaa caaccauucc aaccacaacc aguacaacca caaccacacc      420

aaccacuaca accacaauca cccaugcacc caauacaacc acuacuccca caaccaccac      480

uaccaccaau guucucaaug caaucacuac uaccagaccu cccacucgaa gcauggccag      540

caacagacaa aacaaaaaga gaagaaguag acuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  4854
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt12)

<400>  4854
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacucccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacucaca ccccuaaaau gguaccaaaa caugauaaga caccccuaca      180

caucauacgg auacgaaccc augggaggau ggcuacacca ccaaauaaua ccaguagucu      240

cacaacaaac accacaauca cacgcacucc aaccacacca ccacauccca augguaccag      300

cacaacaacc aggaauacca caacaaccaa ugaugccacu accaggacaa cacucaauga      360

caccaacaca acaccaccaa ccaaaccuac cacuacccgc ccaacaacca uuccaacccc      420

aaccaguaca accacaacca caccaaccac uccaaccaca aucaccaaug cacccaauac      480

aaccacuacu accacaacca ccacucccac caauguucuc aaugcaauca cuacucccag      540

accuaccacu agaagcaugg ccagcaacag acaaaacaaa aagagaagaa guagacuaag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  4855
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt12)

<400>  4855
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccugggguug caagacuacc guuacuauug ggauuacuac      120

uauuaccaag gccaggaaga ccauuagauu uagcagauua uacguaugau uuagcagaag      180

aagacgauag ugaaccauua aauuauaaag auccauguaa agcagccgcg uuuuuagggg      240

acauagcacu agaugaagaa gaucuaagag cauuucaagu acaacaagca guugaccuaa      300

gaagacacac agcuagaaaa ucaucaauua aagccgcugu cccgggaaau acgaguacac      360

cgaguuguca aucuacuaac ggacagccac aacguggugc augcggaaga uggagaggac      420

gcucaaggag ucggagagcg gcaacaagca gaccagaaag ggucuggcca gauggaguaa      480

uaccuuucgu aauaggagga aauuuuacag gaagucaaag agcaguauuc cgucaagcua      540

ugagacauug ggaaaaacau accuguguaa cguuuuuaga aagaacagau gaagauaguu      600

acauaguguu uacguaucga ccaugcggau guuguucuua cguaggaaga cgagggggug      660

guccccaagc aauaucaaua gguaaaaacu gcgauaaauu cgggauagua guacaugaac      720

uagggcaugu aguuggauuu uggcaugaac acacacgacc cgauagagau agacaugucu      780

caauaguaag ggaaaacaua caacccggac aagaauauaa uuucuuaaaa auggaaccac      840

aagaaguuga aaguuuaggu gaaacguaug acuucgauag uauuaugcau uaugcacgaa      900

auaccuuuag uagaggaauu uuucuugaca cuauaguacc gaaauaugaa guaaauggug      960

uaaaaccacc aauaggucaa agaacaagau uaucaaaagg agauauagca caagcucgaa     1020

aacuguacaa augcccagcu uguggugaaa cauugcaaga uucaacagga aauuucagua     1080

gcccagaaua cccaaacgga uauagugcgc auaugcauug cgucuggagg auuaguguaa     1140

caccagguga gaaaauaaua cuaaauuuua cgaguuuaga cuuauaucga agcagauuau     1200

guugguauga cuauguugaa guuagagaug gauuuuggag aaaagcacca uuaagaggaa     1260

gauuuugugg aucaaaacua ccagaaccaa uaguaaguac agauaguagg cuuuggguag     1320

aguucagaag cucgaguaau uggguaggca aaggauucuu ugcagucuau gaagccauau     1380

guggagggga uguuaagaaa gacuauggac acauacaauc accuaauuau ccggacgauu     1440

accgaccaag caaaguuugu auuuggcgga uucaaguaag cgaagguuuc cacguaggac     1500

uuacauucca aucuuuugaa auugaacgcc augauaguug cgcauacgac uaucuagaag     1560

uaagagaugg ucauagcgaa aguucaacac uaauuggaag auacugcgga uaugaaaaac     1620

cugacgauau aaaaucaaca agcagucgau uauggcuaaa auuugugagu gacggaagca     1680

uaaauaaagc uggcuucgcu guaaacuuuu ucaaagaagu agaugaaugu aguagaccaa     1740

auaggggcgg augugaacaa cguuguuuaa auacuuuagg cucguauaaa ugcagcugug     1800

aucccggaua ugaacucgca ccagauaaaa gaagauguga agcagcaugu ggaggauuuu     1860

ugacaaaacu uaaugguucc auaaccaguc caggguggcc aaaagaauau ccgccaaaua     1920

aaaauugcau uuggcagcua guagcuccaa cucaauaccg uaucaguuua caauucgacu     1980

ucuuugaaac agaaggcaau gacguaugca aauacgauuu uguagaaguu agaucugggc     2040

uaaccgcuga caguaaauua cauggaaaau uuuguggcuc agaaaaacca gaaguaauca     2100

caucacaaua caauaacaug agagucgagu uuaaaagcga uaacacaguu aguaagaaag     2160

guuuuaaagc ccauuucuuu agugauaaag augaaugcuc aaaagauaau ggaggguguc     2220

aacaagauug cguaaauaca uuuggaagcu acgaaugcca auguagaucc ggauuuguac     2280

uccaugauaa uaaacacgau uguaaagaag caggauguga ccacaaagua accucuacau     2340

cggggacuau cacgagucca aacuggccag auaaauaccc uucaaagaaa gaaugcacuu     2400

gggcgaucag uucuacucca ggacauaggg uuaaauuaac auuuauggaa auggacauag     2460

aaucacaacc ugaaugugcu uaugaccauu uagaaguuuu ugauggaaga gaugcuaaag     2520

cgccuguuuu aggucgguuu ugcggaagua aaaagccuga accugucuua gccacuggcu     2580

caaggauguu uuuaagguuu uauucagaca acucagucca aagaaaagga uuucaagcaa     2640

gucaugcgac agaaugcgga ggccaaguac gagcagaugu aaaaacaaaa gaucuuuauu     2700

cucaugcaca auuuggugau aauaauuauc cuggaggagu ugauugugag uggguaauag     2760

uagcagaaga agguuaugga guugaauuag uauuucaaac guuugaagua gaagaagaaa     2820

ccgauugcgg uuaugacuac auggaacuau ucgaugguua ugauucaaca gcuccuagau     2880

uaggaagaua uuguggguca ggcccgccag aggaaguaua uagugcagga gauagcguuc     2940

uaguaaaauu ucacagcgac gacacaauaa ccaagaaagg auuccaucua cgcuauacau     3000

caacuaaauu ccaagauaca cuacauagca gaaaauaagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  4856
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt12)

<400>  4856
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgcaggaa caagaugucu acuagcacua uuacuuccac      120

aaguucuacu aggaggagca gcuggauuag uaccagaauu aggaagaaga aaauuugcgg      180

cagcaucauc uggaagaccc aguucacaac caucagacga aguauuauca gaauuugaac      240

uuagacuacu uagcauguuc ggauuaaaac aacgucccac accaucuaga gaugcaguag      300

uaccacccua uaugcuugac cuauacagac gucacagcgg ccaaccagga ucaccagcac      360

cagaccauag acuagaaaga gccgcaucaa gagcaaacac aguaagauca uuccaccaug      420

aagaaagcuu agaagaauua ccagaaacau cagguaaaac uacaagaagg uuuuucuuua      480

acuuaagcuc uauaccaaca gaagaauuua uaacaucagc agaauuacaa guauucagag      540

aacaaaugca agacgcacua ggcaauaaua gcagcuuuca ccacagaaua aauauauaug      600

aaauuauaaa accagcaaca gcaaacucaa aauuuccagu aacaagacua uuagacacac      660

gacuaguaaa ucaaaaugca ucaagauggg aauccuucga cguaacacca gcaguaauga      720

gauggacagc acaaggacac gcaaaccaug gauuuguagu agaaguagcu cacuuagaag      780

aaaaacaagg aguaaguaaa cgucauguaa gaauuagcag aaguuuacau caagacgaac      840

auuccugguc ucaaauuaga ccacuacuag uaacauucgg acaugacgga aaaggacacc      900

cacuacacaa aagagaaaaa cgacaagcaa aacauaaaca acguaaaaga uuaaaauccu      960

cauguaaaag acauccauua uacguagauu ucucagacgu aggauggaac gacuggauag     1020

uagcaccacc cggauaccac gcuuucuauu gccauggaga augcccauuc ccacuugcag     1080

accaucuaaa cagcacaaau cacgccauug uacaaacauu aguaaacagc guaaacucca     1140

aaauaccaaa agcaugcugc guuccaacag aauuaagcgc aauaucaaug uuauacuuag     1200

acgaaaauga aaaaguagua cuaaaaaauu accaagacau gguaguagaa ggcuguggau     1260

gccgcuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  4857
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt12)

<400>  4857
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaccaggaa auagaaugcu uaugguagua uuacuaugcc      120

aaguauuacu aggaggugca ucccaugccu cauuaauacc agaaaccggc aaaaaaaaag      180

uagcugaaau acaaggacau gcaggaggaa gaagauccgg acaaucacac gagcuacuaa      240

gagacuuuga agcuacauua uuacaaaugu uuggauuacg aagaagacca caaccuucaa      300

aaucagcugu cauuccagau uauaugagag acuuauauag auuacaaucu ggugaagaag      360

aagaagaaca aauccacuca acuggacugg aauauccaga aagaccagcu ucaagagcua      420

auacuguucg uucauuucau cacgaagaac auuuagaaaa cauaccagga acaagcgaaa      480

auagugcauu uagauucuua uucaaccuau ccagcauucc agaaaacgaa guaauaucaa      540

gugcagaauu aagauuauuu cgugaacaag uagaucaagg accagacugg gaaagaggau      600

uucacagaau uaacauauau gaaguuauga aaccaccugc agaagucgua ccaggucacc      660

uaauaacaag auuauuagau acaagacuag uacaucauaa cgucacaaga ugggaaacuu      720

uugacguauc accagcagua uuacgaugga cacgagaaaa acaaccaaau uacggucuag      780

caauagaagu aacacaccua caucaaacaa gaacccacca aggacaacau guacgaauau      840

caagaucauu accacaagga agcggaaacu gggcacaauu aagaccacua cuaguuacuu      900

uuggacacga uggaagagga cacgcacuaa cacggagaag aagagcaaaa cguucaccaa      960

aacaccauuc ucaaagagca agaaaaaaaa auaaaaacug cagacgacau agcuuauaug     1020

uagauuucuc agauguaggg uggaaugacu ggauaguagc accuccagga uaccaagcau     1080

uuuacuguca cggugacugu ccauuucccu uagccgauca cuuaaacuca acaaaucaug     1140

caauaguaca aacacuagua aacaguguaa acucaaguau accuaaagca ugcugcguac     1200

caacagaacu aucagcaauu ucaauguuau accuagacga auaugacaaa guuguauuaa     1260

aaaauuauca agaaaugguu guagaaggau guggauguag auaaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  4858
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt12)

<400>  4858
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaggacuag guagaagggc ccaauggcua uguugguggu      120

ggggucuauu auguucaugu uguggacccc cuccucuaag accaccauua ccagcugcug      180

cagcagcagc agccggcggg caauuacuag gagauggagg cucgccagga agaacagaac      240

aaccaccacc aucaccacaa ucaucaucag guuuccuaua cagacgacuu aaaacacaag      300

aaaaacgaga aaugcaaaaa gaaauauuau cuguuuuagg ucuaccacau agaccuagac      360

cacuacaugg ccuacaacaa ccucaaccuc cagcccuucg ccaacaagaa gaacaacaac      420

aacaacaaca auuaccaaga ggugagccac cacccgguag auuaaaauca gcuccuuuau      480

ucauguuaga uuuauacaac gcccuauccg ccgauaauga ugaagaugga gcaucagaag      540

gcgagaggca acaaucaugg ccgcaugaag cagcuucauc aucacaacgc cgacaaccac      600

cuccuggugc ugcacaucca uuaaaucgua aaagccuacu ugcaccagga ucaggaucug      660

gaggagccuc accacuaaca agcgcacaag auucagcauu ucuaaaugac gcugauaugg      720

ucaugaguuu uguaaaucua guagaauacg auaaagaguu cucuccaaga caaagacauc      780

auaaagaauu uaaauuuaau cuaucucaaa ucccagaagg agaaguagua acagcggcag      840

aauuuagaau auauaaagau uguguaaugg gaucauucaa aaaucaaacu uuucuaauuu      900

caauauacca aguauuacaa gaacaucaac aucgcgacuc agaccucuuu uuacucgaca      960

cccgaguugu uugggcaucc gaagaaggcu ggcuagaauu ugauauuaca gcaacaucaa     1020

auuuaugggu aguaaccccu caacauaaca uggguuuaca auuaagugua guaacaagag     1080

acggaguuca cguccaccca agagcugcag gauuaguagg aagagaugga ccauaugaca     1140

aacaaccauu caugguugca uucuuuaaag uuagugaagu ucauguacga acaacaagau     1200

cagcaaguuc aagaagaaga caacaaucua gaaaccgaag uacacaauca caagauguug     1260

cacgaguauc aucugccagu gacuauaauu caucagaauu aaaaacagca uguagaaaac     1320

acgaauuaua cguaucauuu caagauuuag guuggcaaga cuggauaaua gcaccaaaag     1380

gauacgcagc aaauuauugu gacggcgaau guucauuucc uuuaaaugca cauaugaaug     1440

caacaaacca ugcaauaguc caaacauuag uccacuuaau gaauccagaa uacguaccaa     1500

aaccuuguug ugccccaaca aaauuaaaug caaucucagu acuauacuuc gaugauaauu     1560

caaauguaau auuaaagaaa uaccgaaaua ugguaguaag agcuugcggc ugucacuaag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  4859
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt12)

<400>  4859
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caugucagau cacuuagagc agcagcccca cauucuuucg      120

uagcauuaug ggcaccauua uucuuauuaa gaagcgcacu agcagacuuu ucauuagaca      180

augaaguaca uaguagcuuu auacauagac gccuaagauc acaagaaaga cgagaaaugc      240

aaagagaaau ccuaucaaua uuaggauuac cacauagacc aagaccucau cuacaaggaa      300

aacacaacuc cgcuccaaug uucauguuag accuauauaa cgcaauggcu gucgaagaag      360

gaggaggucc aggaggacaa gguuuuaguu aucccuacaa agcaguauuu agcacacaag      420

gcccaccacu cgcaagcuua caagauuccc auuuccuaac agaugccgau augguuauga      480

guuucguuaa ucuuguagaa cacgauaaag aauucuucca cccuagauau caccaucgag      540

aguucagauu cgaucuuuca aaaauaccag aaggagaagc cguuaccgca gcagaauuua      600

gaauauauaa agauuacauc cgcgaacgau uugacaauga aacauucaga auaucaguau      660

aucaaguacu acaagaacau cuagggagag aaucagaucu auuuuuauua gacucuagaa      720

cacuaugggc aucagaagaa ggaugguuag uuuucgauau aacagccaca agcaaucacu      780

ggguaguaaa cccuagacac aacuuaggau uacaauuaag cguagaaaca cucgacggcc      840

aaaguauaaa ccccaaacua gcaggacuaa uaggacgaca cggcccacaa aacaaacaac      900

cauuuauggu cgccuuuuuc aaagcuacag aaguacauuu ccgaucaaua cgaucuacag      960

gauccaaaca aagaucacaa aacagaucua aaacaccaaa aaaucaagaa gcauuaagaa     1020

uggccaaugu agcagaaaau agcucaucag aucaacgaca agcaugcaaa aaacaugaac     1080

uauacgugag uuucagagau cucggauggc aagauuggau aauagcacca gaaggauaug     1140

cagccuauua uugugaaggu gaaugugcau uuccacuaaa uucuuacaug aaugcaacca     1200

aucacgcaau aguucaaaca cuaguacacu uuauaaaccc agaaacagua ccaaaaccuu     1260

guugcgcacc aacacaauua aacgcaaucu caguauuaua cuucgaugau aguucuaacg     1320

uaauauuaaa aaaauacaga aacaugguag ucagagcaug cgguugucac uaaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  4860
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt12)

<400>  4860
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagcaucag cagcacuacu augccuacua cuaacagcag      120

cagcauucuc accacaagga cuagcacaac caguaggaau aaacacauca acaacaugcu      180

gcuacagauu cauaaacaaa aaaauaccaa aacaaagacu agaaucauac agaagaacaa      240

caucaucaca cugcccaaga gaagcaguaa uauucaaaac aaaacuagac aaagaaauau      300

gcgcagaccc aacacaaaaa uggguacaag acuucaugaa acaccuagac aaaaaaacac      360

aaacaccaaa acuauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  4861
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt12)

<400>  4861
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuacucacgu ugauaauauu auuaccagua guaucaaaau      120

ucucuuuugu uagccuaagu gccccacaac auuggucuug uccagaaggg acguuagccg      180

ggaauggaaa caguacaugu gugggaccug ccccauuuuu aauauuuuca cacggaaauu      240

ccaucuuuag aaucgauacu gaagggacaa auuaugaaca auuaguugua gaugccggug      300

uaucaguaau cauggacuuc cauuauaaug aaaaacggau uuacuggguu gaucucgaaa      360

gacaacuacu ucaaagagug uuuuuaaaug ggaguaggca agaaagaguc uguaauauug      420

agaaaaaugu aucaggaaug gcuauaaauu ggauaaacga agagguaaua uggucuaauc      480

aacaagaagg uauuauaacu gugacugaua ugaaaggaaa uaacucacau auccuccuau      540

cugcucuaaa auauccugcu aacguggcag uugauccagu cgaacgauuu aucuuuuggu      600

caucagaggu cgcaggaucg cuauauagag cagacuuaga ugguguagga guaaaagcau      660

uacuagaaac cagcgagaaa auaacugcag uaaguuuaga uguacucgac aaaagauuau      720

ucuggauaca auacaauaga gaaggaucaa auucacuaau auguucuugu gacuaugaug      780

gcggaagcgu ccacauaucu aaacacccca cacaacauaa uuuauuugcg augaguuuau      840

uuggugauag aauauuuuau aguacgugga aaaugaaaac cauauggaua gcuaauaaac      900

auacaggaaa agacaugguc cgaauaaacc uacacucauc cuuuguaccu cuaggggaau      960

ugaaaguagu acauccacua gcacaaccaa aagcggaaga cgacacaugg gaaccggaac     1020

aaaaacucug uaaacucaga aaggguaauu guucgaguac uguaugugga caagaucuac     1080

aaagccauuu auguaugugc gcagaaggau augcuuuauc aagagaucga aaauauugcg     1140

aagaugucaa ugagugugca uuuuggaauc auggauguac ccuuggcugc aaaaauaccc     1200

caggcucaua uuauugcacu uguccaguag gauuuguauu guuaccugau ggaaagcgau     1260

gucaucaacu uguaaguugu ccacgaaaug uuagugaaug uucacaugau ugcguguuaa     1320

caucagaagg cccauuaugc uucugcccag aaggaucagu guuagaaaga gauggcaaaa     1380

cuugcagugg augcaguagc ccagacaaug guggauguag ucaauuaugu guuccguuau     1440

ccccaguguc gugggaaugu gacuguuuuc caggauauga uuuacagcua gacgaaaaau     1500

cuugcgcagc aagcggucca caacccuuuu uacuauuugc aaauucccaa gacauucguc     1560

acaugcauuu ugaugguacu gauuauggua cauuauuauc acaacaaaug gguaugguau     1620

augcauuaga ccaugauccu gucgaaaaca aaauauauuu cgcucauaca gccuuaaagu     1680

ggaucgaacg cgcuaacaug gauggaaguc aaagagaaag gcucauugaa gaaggagucg     1740

auguacccga aggcuuagca guagacugga uaggccgccg auuuuauugg acagauagag     1800

guaaaagucu uauaggacgu ucagacuuaa auggaaaaag aaguaaaauu auaacaaaag     1860

aaaacauauc acaaccuagg ggaauagcag uacauccaau ggcaaaacgc cucuuuugga     1920

cagauacagg cauaaauccu agaauugaaa guucuagcuu acagggacua ggccggcuag     1980

uaauugccuc aucagaccua auauggccaa gugggauaac cauagauuuu cucacggaca     2040

aauuguauug gugcgaugca aaacagucag uaauagaaau ggcuaaucuc gaugguucaa     2100

agagaaggag auuaacacag aacgauguug gucacccauu cgcaguagca guauucgagg     2160

auuacgucug guuuucggau ugggcaaugc caaguguaau gagaguaaac aaaagaacag     2220

guaaagauag aguacgauua caaggaucca uguuaaagcc cuccucauua guagucguuc     2280

auccauuggc uaaaccagga gccgacccau gcuuauacca aaaugguggu ugugaacaca     2340

uuuguaagaa aagauuagga acagccuggu guucaugcag agaaggcuuc augaaagcau     2400

cagauggaaa aacaugccua gcauuagaug gacaccaacu acuagcagga ggagaaguug     2460

accucaaaaa ccaaguaacg cccuuagaua uauuaaguaa aacucgaguu agugaggaca     2520

acauaacaga aagucaacac auguuagugg cugaaauaau gguaagugau caagacgauu     2580

gugcaccagu aggauguuca auguaugcac gcuguaucuc agaaggcgaa gaugcaacuu     2640

gccaaugccu aaaaggcuuc gcgggcgaug gaaaacuaug uucagacaua gaugaaugug     2700

aaaugggugu uccuguaugu cccccagcgu ccucaaaaug cauaaauacc gaaggcggcu     2760

auguaugucg uuguucagaa ggguaccaag gugauggaau ccauuguuua gauauagacg     2820

aaugucaauu aggcgaacau aguuguggug agaacgcuuc uugcaccaac acagaaggag     2880

guuacacaug uaugugcgca gggaggcuaa gugagccagg auuaauuugu ccagauagua     2940

caccaccucc ccaccuaaga gaggaugauc aucauuacuc aguaagaaau ucagauagug     3000

aauguccauu aucucacgau gguuacugcc uacaugacgg uguaugcaug uauauagaag     3060

ccuuagauaa auaugcuugu aacuguguag ucggcuacau aggagaaagg ugucaauaua     3120

gggaccuaaa auggugggaa uuacgacaug cuggccaugg gcaacaacaa aaaguaauag     3180

uuguagcagu cugugucgua guucuaguaa ugcuccucuu acuaucccua uggggugcuc     3240

auuauuaccg aacgcaaaaa cuucugagua aaaauccuaa aaauccauac gaagaaucau     3300

caagagaugu acgaucaagg agaccagccg auacagaaga ugggaugucg ucuugcccac     3360

agccaugguu cguuguaaua aaagaacacc aagauuugaa aaacggaggu caaccugucg     3420

caggagagga uggacaagcu gcagauggua guaugcaacc cacaaguugg agacaagaac     3480

cccaauuaug cggaauggga acggaacaag ggugcuggau uccaguaucg agcgacaaag     3540

ggucuugccc ccaaguaaug gaaagaucgu uccauaugcc cucauacgga acgcaaacuu     3600

uagaaggagg aguagagaaa ccacauuccu uacuaagcgc aaauccauua uggcaacaac     3660

gagcuuuaga uccaccacau caaauggaau ugacacaaua aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  4862
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt12)

<400>  4862
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagcaggaa gaagaaugga aaugcuaugu gcaggaagag      120

uaccagcacu auuacuaugu cuaggauucc aucuauuaca agcaguauua aguacaacag      180

uaauaccaag cuguauacca ggagaaagcu cagacaauug cacagcauua guacaaacag      240

aagacaaucc aagaguagca caaguaagca uaacaaaaug cucaagugau augaauggau      300

auugcuuaca cggacaaugu auauaucuag uagacaugag ccaaaacuau ugcagaugcg      360

aaguaggaua cacgggagua agaugugaac acuucuuucu aacaguacau caaccacuau      420

caaaagaaua cguagcauua acaguaauau uaauaauacu auuucuaaua acaguaguag      480

gaagcacaua cuauuucugu agaugguaca gaaacagaaa aucaaaagaa ccaaaaaaag      540

aauaugaaag aguaacauca ggagauccag aacuaccaca aguauaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  4863
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt12)

<400>  4863
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagaaggag aaauaacaac auucacagca cuaacagaaa      120

aauucaaccu accaccagga aacuacaaaa aaccaaaacu acuauacugc ucaaacggag      180

gacacuucuu aagaauacua ccagacggaa ccguagacgg aacaagagac agaucagacc      240

aacacauaca acuacaauua ucagcagaau caguaggaga aguauacaua aaauccacag      300

aaacaggaca auacuuagca auggacacag acggacuacu auacggauca caaacaccaa      360

acgaagaaug ccuauuccua gaaagacuag aagaaaacca cuacaacaca uacauaucaa      420

aaaaacacgc agaaaaaaac ugguucguag gacuaaaaaa aaacggauca ugcaaaagag      480

gaccaagaac acacuacgga caaaaagcaa uacuauuccu accccuacca guauccucag      540

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  4864
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt12)

<400>  4864
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaggggugg gaggaggaga cguagaagac guaacaccaa      120

gaccaggagg augucaaaua aguggaagag gagcaagagg uuguaaugga auaccaggag      180

cggcagcaug ggaagcagca uuaccgagaa gaagaccgag aagacaccca aguguaaauc      240

cuagaucaag agcagcugga agcccaagaa cacgaggaag aagaacagaa gaaaggccua      300

guggaaguag auuaggggac agaggaagag gaagagcauu gccaggagga agacuaggcg      360

gaagaggaag aggaagagca ccagaaagag uaggagguag aggaagagga agaggaacag      420

cagcaccaag agcagcacca gcagcaaggg gaaguagacc aggaccagcg ggaacaaugg      480

cagcaggaag uauaacaaca cuuccagcau ugccagaaga uggaggaagu ggcgcauuuc      540

cgccaggaca uuuuaaagau ccaaagagau uauacuguaa aaauggaggu uuuuuuuuaa      600

gaauacaucc agauggaaga guagauggag uaagagaaaa aagugaucca cauauaaaau      660

uacaauuaca agcagaagaa agaggaguag uaaguauaaa aggaguaugu gcaaacagau      720

auuuagcaau gaaagaagau ggaagauuac uagcaaguaa auguguaaca gaugaauguu      780

uuuucuuuga aagauuagaa aguaauaauu auaauacgua ccgaaguaga aaauauacaa      840

guugguaugu agcguuaaaa agaacaggac aauauaaauu aggaagcaaa acaggaccgg      900

gacaaaaagc aauauuauuu uuaccuauga gugcgaaaag uuaaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  4865
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt12)

<400>  4865
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uacuaacaug gauacuacca acacuacuau      120

acagaagcug cuuccacaua auaugcuuag uaggaacaau aagccuagca uguaacgaua      180

ugacaccaga acaaauggca acaaauguaa acugcagcuc acccgaaaga cacacaagau      240

cauacgacua cauggaaggc ggagacauaa gaguaagaag acuauucugc agaacacaau      300

gguacuuacg aauagacaaa agaggaaaag uaaaaggaac acaagaaaug aaaaacaacu      360

acaacauaau ggaaauaaga acaguagcag uaggaauagu agcaauaaaa ggaguagaau      420

cagaauucua ccuagcaaug aacaaagaag gaaaacuaua cgcaaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa uuaauacuag aaaaccacua uaacacauac gcaagcgcaa      540

aauggacaca caacggagga gaaauguucg ucgcacuaaa ccaaaaagga auaccaguaa      600

gaggaaaaaa aacaaaaaaa gaacaaaaaa cagcacacuu ccuaccaaug gcaauaacau      660

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  4866
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt12)

<400>  4866
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuacuac caagcguagu acuaaaacua uucuuagcag      120

caguacuaag cgcacuagua acaggagaaa gccucgaaag acuacgaaga ggccuagccg      180

cagguacauc aaacccagac ccaccaacag uaucaacaga ccaauuacua ccacuaggag      240

gaggaagaga cagaaaagua agagaccuuc aagaagcaga ccuagaucua cuaagaguua      300

cauuaucauc aaaaccacaa gcacuagcaa caccaaacaa agaagaacac ggaaaaagaa      360

aaaaaaaagg aaaaggacua ggcaaaaaaa gagacccaug cuuaagaaaa uacaaagacu      420

ucugcauaca cggagaaugc aaauacguaa aagaacuaag agcaccauca ugcauaugcc      480

acccaggaua ucacggagaa agaugccacg gauuaagccu accaguagaa aauagacuau      540

acacauacga ccacacaaca auacuagcag uaguagcagu aguacuauca ucaguauguc      600

uacuaguaau aguaggacua uuaauguuca gauaccacag aagaggcgga uacgacguag      660

aaaacgaaga aaaaguaaaa cuaggaauga caaauucaca cuaaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  4867
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt12)

<400>  4867
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uggguuacaa aacuauuacc cgccuuacua uuacagcaug      120

ucuuacuaca ucuauuacua uuacccauag cuauaccaua ugcugaaggc caacguaaaa      180

gaagaaauac aauucaugaa uuuaaaaaau cagcuaaaac aacauuaaua aaaauagacc      240

cagcuuugaa aauaaaaaca aaaaaaguaa acaccgcaga ucaaugugca aaucgaugua      300

cacgaaacaa aggauuaccc uuuacaugua aagcauuugu auuugauaaa gccagaaaac      360

aaugcuugug guuuccuuuc aacucaaugu caucaggagu aaaaaaagaa uuuggccacg      420

aauucgaucu auaugaaaau aaagauuaua uaagaaauug uauaauagga aaaggacgau      480

cauauaaagg aacaguaagu auaacaaaaa gcggaauaaa augucaaccg ugguccagua      540

ugauaccaca ugaacauuca uuuuuaccau caucauaccg agguaaagac uuacaagaaa      600

auuacugcag aaauccacga ggagaagaag gaggaccaug gugcuucaca ucaaauccag      660

aaguucgaua ugaaguaugu gacauuccuc aauguucaga aguagaaugc augacuugua      720

auggagaauc uuauagaggu uuaauggacc auacagaaag uggaaaaaua ugccaacgau      780

gggaucacca aacaccacau agacacaaau uccuaccaga aagauaccca gacaaaggau      840

uugaugauaa cuacuguagg aacccggaug gacaaccaag gccauggugc uauacauuag      900

auccacauac cagaugggaa uauugugcaa uaaaaacuug ugcagauaau acaaugaaug      960

acaccgaugu accacuugaa accacagaau guauacaagg ucaaggagaa ggauaucgag     1020

gaacaguaaa uacaauaugg aauggaauac cgugucaacg augggauagu caauaccccc     1080

augaacauga caugacacca gaaaauuuua aaugcaaaga ucuaagggaa aauuauugua     1140

ggaauccaga uggaucagaa ucaccuuggu guuucaccac agauccaaau auacgcguug     1200

gauauuguuc acaaauacca aauugcgaca ugagucacgg acaggauugc uauagaggua     1260

auggaaaaaa uuauauggga aaccuaucac aaacaagauc aggucuaaca ugcucaaugu     1320

gggacaaaaa cauggaagau uuacauaggc acaucuucug ggaaccagau gcaagcaaau     1380

uaaaugaaaa uuauugucga aauccagaug acgacgcaca uggaccaugg uguuacacag     1440

gaaacccacu aauaccaugg gacuauugcc ccauaucaag augcgaagga gauacuacac     1500

ccacuauagu aaaucuagau cacccuguaa uaucaugugc aaagaccaaa caacucaggg     1560

uaguaaacgg cauaccaacu cgaaccaaua uuggauggau gguuucacua agauaccgca     1620

acaagcauau augcggagga agccuaauua aagaaucaug gguauugaca gcaagacaau     1680

guuucccaag ccgagaccuu aaagauuaug aagcaugguu aggaauacac gacguacaug     1740

gcagaggaga ugaaaaaugc aaacaaguac uuaacguuuc ucaauuaguc uacggaccag     1800

aaggauccga cuuaguacua augaaauuag caagaccagc aguucuagau gauuuuguau     1860

cuacaauaga ucuaccaaac uacggaugua caauaccuga aaaaacaagc ugcaguguau     1920

acggaugggg uuauacuggc cuuauaaauu augacggacu ccuaagggua gcucauuuau     1980

auauaauggg aaaugaaaaa ugcucccaac aucaucgugg aaaaguuaca cuaaaugaau     2040

cagaaauaug cgcaggugca gaaaaaauag guucaggacc augugaggga gauuauggug     2100

gaccauuagu uugugaacaa cauaaaaugc gaaugguccu aggaguaauu guaccaggaa     2160

gaggaugcgc aauaccuaau agacccggaa uuuucgucag aguagcauac uaugcuaaau     2220

ggauacauaa aauaauacua acguauaaag ugccucaauc auaaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  4868
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt12)

<400>  4868
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaaagcag cagccauagg aauagaucuu gguacaacau      120

auucaugcgu aggcguauuu caacauggaa aaguagaaau aauagcaaac gaccaaggca      180

accgaacaac accauccuac guggcuuuca cagacacaga aagacuaauu ggcgaugcag      240

cuaaaaauca aguugcauua aauccacaaa acacaguauu ugacgcaaaa agacucauag      300

gaagaaaauu uggggauccu guaguccaaa gcgauaugaa acacuggccc uuucaaguaa      360

uaaacgacgg cgacaaacca aagguacagg uaaguuauaa gggagaaaca aaagcauuuu      420

accccgaaga aaucagcagc augguauuaa cuaaaaugaa agaaauagcc gaggcauauu      480

uaggauaucc aguuacaaac gcagucauaa cuguaccagc auacuuuaau gauucacaaa      540

ggcaagcaac aaaagaugca ggaguaauag cuggauuaaa cguauuaaga auaauaaacg      600

aaccaacagc agcagcaaua gcguaugguu uagaccgaac aggcaaagga gagagaaacg      660

uacuaaucuu ugaucuagga ggaggaacau ucgauguauc aauauuaaca aucgaugacg      720

gaauauucga aguuaaagca acugcaggag acacacacuu aggaggagaa gauuuugaua      780

acagauuagu aaaccacuuu guagaagaau uuaaacgaaa acauaagaaa gacauuucac      840

aaaauaaaag ggcuguaaga agacuaagaa cagcuugcga aagagcuaaa agaacacuaa      900

gcagcucaac acaagcaagu cuagaaauag acaguuuauu ugaaggaauc gauuucuaca      960

caucaauaac aagagcacga uuugaagaac uauguaguga ccuauuuaga agcacucuag     1020

agccugucga aaaagcauua agagaugcua aauuagacaa agcacaaaua cacgaucuag     1080

uucuaguagg aggaucaacu cgaaucccca aaguacaaaa acuauuacaa gauuucuuca     1140

augguagaga ccucaauaaa aguauuaauc cagaugaagc agucgcauau ggugcugcag     1200

uacaggccgc aauuuuaaug ggggauaaau ccgaaaacgu ccaagaucua uuauuauuag     1260

acguagcacc auuaucacua gguuuagaaa cagcuggagg gguaaugacu gcauuaauaa     1320

aaaggaacag uacaauaccg acaaaacaaa cacaaauauu uacaacauac ucagauaauc     1380

aaccaggagu uuuaauucaa guauacgagg gagaacgcgc aaugacaaaa gacaacaauc     1440

ucuuaggccg guuugaacua ucagguauac cuccagcccc uagagguguu ccacaaauag     1500

aaguaacauu ugauauugac gcuaauggua uccuaaacgu cacagcaacu gacaaaucaa     1560

ccggaaaagc aaauaaaauc acaauaacaa augauaaggg aagacuuagu aaagaagaaa     1620

ucgaaagaau gguacaagag gcagaaaaau auaaagcgga agacgaagua caaagagaaa     1680

gaguaagugc uaaaaacgcg cuugaauccu augcauucaa uaugaaauca gcagucgagg     1740

acgaaggauu aaaaggaaaa auaagugaag cagacaaaaa gaaaguuuua gauaaaugcc     1800

aagaaguuau uucaugguua gaugcaaaua cauuagcaga aaaagacgag uucgaacaua     1860

aaaggaaaga acuagaacaa guauguaauc cuauaauaag cggauuauac caaggugcgg     1920

gagguccagg acccgguggu uucggugcuc aaggaccuaa aggcggcagu ggaaguggac     1980

caacuauaga agaaguagau uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4869
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt12)

<400>  4869
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuaaagcag cagcaaucgg aaucgauuua gggacaacau      120

acagcugugu aggaguauuc caacacggaa aaguugaaau aauagcaaau gaucagggaa      180

acaggacaac uccuagcuau guugcauuua ccgauaccga acgucucauu ggagaugcgg      240

caaaaaauca gguagcauua aacccccaaa acacaguauu ugacgcuaaa agauuaauag      300

gacgaaaauu cggagauccg guuguacaaa gcgacaugaa acacuggcca uuucaaguaa      360

uaaaugaugg agacaaacca aaaguccaag ucucuuacaa aggagaaaca aaagcauucu      420

acccagaaga aauaucaagu auggucuuaa ccaaaaugaa agaaauagca gaagcauacu      480

uaggguaccc aguaacaaau gcaguaauaa caguucccgc auauuuuaac gauagccaaa      540

gacaagcuac uaaagacgca ggaguaaucg caggauuaaa uguacuuaga auuauaaaug      600

agccaacugc agcagcaauu gcauauggau uggacaggac uggaaaagga gaaagaaacg      660

uauuaauauu ugaccuagga ggaggcacau uugacguauc aauauuaacc auagacgacg      720

gaauauucga gguaaaagca acagcaggag acacccauuu aggaggagaa gauuucgaua      780

aucgauuagu aaaucauuuu guagaagaau uuaaaagaaa acauaaaaaa gauauaucac      840

aaaauaaaag agcaguuaga cgauuacgaa cagcuugcga aagagcaaaa agaacccuaa      900

guucuagcac acaagcuagc cuugaaauug auucccuauu ugaaggcaua gauuucuaua      960

caagcaucac ucgagcaaga uuugaagaau uaugcaguga cuuauuuaga ucaacucuag     1020

aaccuguaga aaaagcgcuu agagacgcca aauuagauaa agcacaaauc caugauuuag     1080

ucuuaguagg aggaucaacc agaauaccca aaguacaaaa acuauuacaa gacuucuuca     1140

acggaagaga ucuaaauaaa ucaauaaauc cugacgaggc aguugccuac ggagccgcgg     1200

uacaagcagc aauacuaaug ggagacaaaa gcgaaaacgu acaagaucua uuacuucuag     1260

auguagcacc ucuaaguuua ggauuagaaa cagcaggagg aguaaugacc gcacuaauaa     1320

aaaggaauuc aacgauacca acaaaacaaa cucaaauuuu cacaacauac ucagacaauc     1380

aaccuggagu acuaauacaa guauacgaag gagagagagc aaugacaaaa gauaacaauc     1440

uauugggaag auucgaacua ucaggaauac ccccggcgcc acgaggagua ccgcaaauug     1500

aaguaacuuu ugauauagau gccaauggaa uauuaaaugu aaccgcaacc gauaaaagca     1560

cuggaaaagc aaauaaaaua acaauaacaa augacaaagg aagacuauca aaagaagaaa     1620

uagaacgaau gguccaagaa gcagaaaaau acaaagcaga agacgaagua caacgagaac     1680

gaguuucagc caaaaaugca uuagaaucau acgcauuuaa caugaaaagu gcaguagaag     1740

acgaaggacu aaaaggaaaa aucucagaag cagauaaaaa aaaaguacug gauaaauguc     1800

aagaagucau aaguugguua gacgcaaaua cauuagcaga aaaagacgaa uucgaacaca     1860

aaagaaaaga gcuagaacaa gucuguaacc cuauaauaag uggacuauac caaggagcgg     1920

gaggaccagg accaggaggu uuuggugcac aagguccaaa aggcggaagc ggcagcggac     1980

cuacaauaga agaaguagau uagggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4870
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt12)

<400>  4870
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuacagcaa aaggaauagc uauuggaaua gaucuaggca      120

caacauacag uugcguuggc guuuuucagc auggaaaagu agaaauuaua gcaaaugauc      180

aaggaaaucg caccacuccu ucuuauguag cuuucacaga uacagaacga cuuauaggag      240

acgcugcuaa aaaccaaguu gcaaugaacc cacaaaauac ugucuuugac gcaaaaagac      300

uaauaggccg aaaauucaau gacccaguag uacaagcgga caugaaacuu uggccauucc      360

aagugaucaa cgaagguggu aaaccaaaag uauuaguauc auacaaagga gaaaauaaag      420

cauuuuaccc agaagaaaua agcucuaugg uacugacuaa auuaaaagaa acagcagaag      480

cauuucuagg acacccagua acaaaugcag uaauaacagu acccgcuuac uuuaaugacu      540

cccaaagaca agcaacaaag gacgcaggag uuauagcagg acuuaaugua cuuagaauaa      600

ucaacgaacc aacagcggca gcaauagccu auggauuaga uaaaggagga caaggagaac      660

gacauguauu aauauuugac cuagguggag guacauucga ugucucuaua uuaaccauag      720

acgacggaau auucgaagua aaagcaacag caggggacac ucauuuaggc ggagaagauu      780

uugacaauag auuaguaagc cacuucguag aagaguucaa aagaaaacac aaaaaggaua      840

uaagucagaa uaaacgagca guaagaagac uacgaacagc cugugaaaga gcuaaaagaa      900

cguuaucaag uucaacacaa gcaaaucuag aaauagacag ucuauaugaa ggaauagauu      960

ucuauaccuc aauaacgaga gcuagauuug aagaacuaug cgcagaucua uucagaggca     1020

cacuagaacc aguagaaaaa gcucuacgag augcaaaaau ggacaaagcu aaaauucaug     1080

auauaguccu uguaggggga ucaacaagaa uaccaaaagu acaaagauug uuacaagauu     1140

acuuuaacgg aagagauuua aacaaaucaa uaaacccaga ugaagcugua gcauauggcg     1200

cagcaguaca agcagcaaua cuuaugggag auaaaaguga aaaaguacaa gauuuauuau     1260

uauuagacgu agcaccacua ucccuaggac uagaaacagc aggaggagua augacagcac     1320

ucauaaaaag aaauaguacc auaccaacaa aacaaaccca aauauuuaca acguauagcg     1380

acaaucaacc aggaguacua auacaagugu augaaggaga aagagcaaug accaaagaua     1440

auaaucuucu uggccgauuc gaucucacag gaauaccucc agcaccaaga ggagucccac     1500

aaauugaagu uacauuugac auagacgcca augguauacu aaacguaaca gcuaccgaua     1560

aaaguacagg aaaaguaaac aaaaucacaa ucacaaauga caaagguaga uuaucaaaag     1620

aggaaaucga aagaauggua uuggacgcag aaaaauauaa agcagaagac gaaguacaaa     1680

gagagaaaau agcagcuaaa aacgcucuug aaucauaugc auuuaacaug aaaucaguag     1740

uauccgacga aggacucaaa ggaaaaauaa gcgaaucaga uaaaaauaaa auacucgaua     1800

aaugcaacga acuauuaagc ugguuagaag uaaaucaacu agcagaaaaa gaugaauuug     1860

accauaaaag aaaagaacua gaacaaaugu guaauccaau aauaacuaaa uuauaccaag     1920

gaggaugcac aggaccagcc uguggcacag gauauguucc uggacgaccc gcaacuggac     1980

caacaauaga agaaguugau uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4871
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt12)

<400>  4871
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgcaagag gaccagcgau uggaaucgau cuaggaacaa      120

cguacaguug cgugggagua uuccaacaug gaaaaguuga aauaaucgca aaugaucagg      180

gaaauagaac uacaccauca uacguugcuu uuacagacac cgaaagauug auuggagacg      240

cagcgaaaaa ucaaguagca augaauccaa ccaacacaau cuuugacgca aaaagacuca      300

uaggcagaaa auucgaagac gcaacgguac agagcgauau gaaacacugg ccauuuagag      360

uaguaucaga aggaggaaaa ccaaaaguac aagucgaaua uaaaggagaa acuaaaacau      420

uuuucccaga agaaauaagc aguaugguau uaacaaaaau gaaagaaaua gcagaagcau      480

aucuaggagg aaaaguucau agugcaguaa uaacuguacc agcauauuuu aaugauucac      540

aaagacaagc cacgaaagau gccggaacaa uaaccggauu aaauguacug agaauaauaa      600

acgaaccaac agcugccgca auagcauacg ggcuagauaa gaaaggaugu gccggaggug      660

agaaaaaugu auuaauauuu gacuuaggcg gaggaacauu ugauguauca auacuaacaa      720

uugaagacgg aauauucgaa guuaaaagua cggcgggaga uacacauuua ggaggagaag      780

auuuugauaa cagaauggua agucauuuag cagaagaguu caaacgaaaa cacaagaaag      840

acauaggacc uaauaaaaga gcaguaagaa gacuaaggac ugcaugcgaa agagcaaaaa      900

gaacacuaag uagcaguaca caggcgagua uagaaauaga cucauuauau gaaggagucg      960

auuuuuauac uucaauaacg agagcaagau ucgaagaacu caaugcggau uuauuuagag     1020

gaacauugga accaguagaa aaagcacuua gagaugcaaa acuagacaaa ggacaaaucc     1080

aagaaauagu ccuaguaggu ggcucaacaa gaauaccaaa aauccaaaaa cuauugcaag     1140

auuucuucaa uggcaaagaa uuaaauaagu caaucaaucc agacgaagca gucgcauacg     1200

gagcagcagu ucaagcagca auauugauag gggauaaauc agaaaaugua caagaccuau     1260

uauuguuaga uguaacacca uuaagucucg guauagaaac ugcaggagga guaaugacac     1320

cucuaauaaa aagaaacaca acuauaccaa caaaacaaac acaaacauuu acaacauaca     1380

gugacaauca aucaagugua uuaguacaag uauacgaagg agaaagagca augacgaaag     1440

acaacaaucu auuaggaaaa uuugaucuaa cagggauucc uccagcaccg agagguguac     1500

cacaaaucga aguaacauuu gacauagacg caaauggaau auuaaacgua acagcagcag     1560

auaaaucaac cgggaaagaa aacaaaauca caauaacuaa cgauaaaggg agguuaagca     1620

aagaugauau cgaucguaug guccaagaag cagaaagaua uaaaagcgag gaugaggcaa     1680

acagagacag aguagcagcg aaaaaugcau uagaaucuua cacguauaau auaaaacaaa     1740

cuguagagga cgaaaaauua cggggaaaaa uauccgaaca agauaaaaac aaaauauuag     1800

auaaaugcca agaagucaua aacugguuag acagaaauca aauggcagaa aaagaugaau     1860

acgaacauaa acagaaagaa cuagaaagag uguguaaucc cauaauauca aaauuauacc     1920

aaggaggucc aggaggugga agcgggggag gaggaagugg cgcaagcgga gggccaacaa     1980

uagaagaagu agauuaggga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  4872
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt12)

<400>  4872
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucuguaguag gaauagaccu cggauuucaa aguuguuaug      120

uagcagucgc ucgggcagga ggcauugaaa caauugcaaa ugaauacuca gacaggugua      180

caccagcaug cauaaguuuc ggaccaaaaa accgaucaau aggcgcagca gcaaaaagcc      240

agguaauauc aaaugcuaaa aauacaguac aaggguuuaa aagauuccac ggaagagcau      300

uuucagaucc uuuuguagaa gcugaaaaaa guaauuuagc cuacgacaua guucaguuac      360

caacaggauu aacaggcaua aaaguaacuu auauggaaga agaacgaaac uuuacaacug      420

aacaaguaac agcaaugcua cuaucuaaau uaaaagaaac ugcagaaagu guuuuaaaaa      480

aaccaguagu agacugugua guaagcgugc cauguuuuua uacagacgcg gaaagaagau      540

cggucaugga ugcaacacaa auagcagggc ucaauugccu uaggcucaug aaugaaacaa      600

cugcaguagc ucuagcuuac ggaauuuaua aacaagacuu gccagcacua gaagagaaac      660

caagaaacgu cguuuucguc gauaugggac acucagcaua ccaaguaagu guuugcgcau      720

uuaauagagg aaaacuaaaa guauuggcaa cagcauuuga cacaacacua ggagguagaa      780

aauucgauga aguacuaguc aaucacuuuu gugaagaauu cggaaaaaag uacaaacuag      840

auauuaaauc aaaaauuaga gcauuauugc gacuaagcca agaaugugaa aaacuaaaaa      900

aauuaauguc agcaaaugca ucugacuuac cauuaagcau ugaaugcuuu augaaugaug      960

uagaugucuc aggaacaaug aaucgaggaa aauucuuaga aauguguaac gaucuacuag     1020

cuagagucga acccccucuc aggucagugc uagaacaaac aaaacuaaaa aaagaagaua     1080

uauacgccgu ggaaaucgua gguggagcua ccagaauacc agcugugaaa gagaaaauaa     1140

guaaauucuu cggcaaagaa uuaucaacaa cacuaaaugc agacgaagca guuacccgag     1200

gaugugcuuu acaaugugca auuuuaucgc cagcauucaa aguacgagaa uucucaauaa     1260

cagauguagu accuuauccc auaucucuua gauggaauuc accagcagaa gagggaagcu     1320

cagauugcga aguauuuuca aaaaaccacg cugcaccguu uuccaaagua cugacuuucu     1380

acagaaaaga accauuuacg uuagaagcau acuauucauc uccccaagac uuaccauacc     1440

cagaucccgc cauugcacaa uucucaguac aaaaggugac cccacaaucc gacggaucca     1500

gcucaaaagu gaaaguaaag guaagaguaa auguacacgg cauauuuuca guaaguucag     1560

cgucccucgu agaaguucac aaaagcgaag aaaacgaaga accaauggaa acagaccaaa     1620

acgcaaaaga agaagaaaaa augcaaguag accaagaaga accccaugua gaagaacaac     1680

aacaacaaac acccgcagaa aacaaagccg aaagugaaga aauggaaaca ucacaagcag     1740

gcaguaaaga uaagaaaaug gaucaaccac cacaggcaaa aaaagcuaaa guaaaaacaa     1800

guacaguaga ucucccaauu gaaaaucaac uacuauggca aaucgauaga gagauguuaa     1860

accuauacau cgaaaaugaa ggaaaaauga ucaugcaaga caaacuagaa aaagaacgga     1920

acgaugcaaa aaacgcagug gaagaguaug uauaugaaau gcgagacaaa cuaucaggag     1980

aauaugaaaa auuuguuagc gaggaugaca gaaauucauu caccuuaaaa cuagaagaua     2040

cugaaaauug guuauaugaa gacggagaag accaaccuaa gcaaguguac guugauaagc     2100

uagcagagcu caaaaauuug ggccagccaa uaaaaauaag auuccaagaa uccgaagaaa     2160

gaccgaaacu auucgaagaa cuugggaaac aaauacagca auacaugaag auaaucucau     2220

cauuuaaaaa caaagaagau caauacgacc acuuagacgc agcagacaug acuaaaguag     2280

aaaaaucuac gaacgaagca auggaaugga ugaauaacaa acuaaaucuu caaaacaaac     2340

aaucacuuac aauggaccca guaguaaaaa gcaaagaaau cgaagcgaaa auaaaagaau     2400

uaacgagcac auguucaccu auaauaucaa aaccaaaacc aaaaguggaa ccaccuaaag     2460

aagaacaaaa aaaugcagaa caaaauggac cgguagacgg gcaaggagac aauccaggac     2520

cucaagcagc cgaacagggc acagacacag caguaccauc agacagcgac aaaaaacuac     2580

cggaaaugga cauagacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  4873
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt12)

<400>  4873
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agugugguag gaauagaccu uggauuccua aauugcuaca      120

uagcuguagc aagaucagga ggcauugaaa caauagcaaa cgaauauagc gaccgaugca      180

caccagcaug cauaucauua ggaaguagga cuagagccau agguaaugcg gcaaaaucac      240

aaauaguaac caauguaaga aacaccauac auggauucaa gaaacuacac ggacgcagcu      300

ucgacgaucc aauaguacaa acagaaagaa uuagacuacc cuacgaacua cagaaaaugc      360

caaacggauc ugcaggaguc aaaguaagau accuugaaga agaacggcca uuugcaauug      420

aacaagugac aggaauguua cuugcaaaac uaaaagaaac aagugaaaau gcauuaaaga      480

aaccaguagc agauugcgua auuucaauac ccagcuucuu cacagacgca gaaagaagaa      540

guguaauggc agcagcacaa guagccggac uaaacugucu aagacuaaug aacgaaacaa      600

cagcuguagc uuuagcauac ggcauauaua aacaagaucu accaccacua gaugaaaaac      660

caagaaacgu aguuuuuaua gauaugggac acucagccua ccaaguccua guaugugcuu      720

ucaacaaagg aaaauuaaaa guacuugcaa caacauuuga uccauaucua ggggguagaa      780

auuucgacga agcucuagua gacuacuuuu gugaugaguu caaaacaaaa uacaaaauua      840

augucaaaga aaauucaaga gcauuacuca gacuuuacca agaaugcgaa aaauuaaaga      900

aacuaauguc ugcaaaugca uccgauuuac cgcuaaauau cgaaugcuuu augaaugauc      960

uugacguauc aagcaaaaug aacagagcac aauuugaaca acuaugugca uccuuauuag     1020

caagaguaga accuccccua aaagcgguaa uggaacaagc uaaucuccaa cgcgaagaca     1080

uaagcucaau agaaauagua ggcggagcaa ccagaauacc ggcagugaaa gaacaaauaa     1140

caaaauuuuu cuuaaaagac auuucuacaa cuuuaaacgc agacgaagcu guggcuagag     1200

guugcgcacu ucaaugcgcc aucuuaucac cagcguucaa aguccgcgag uucaguauaa     1260

cagaccuggu accauacagu aucacgcucc gauggaaaac uagcuuugaa gacggcucug     1320

gggaaugcga aguauucugu aaaaaucacc cagcaccauu uagcaaagua auaacauuuc     1380

acaagaaaga accauucgaa cuagaagcau ucuacacaaa cuuacaugaa guucccuacc     1440

cagaugcacg aauagguagu uucacaauac aaaauguauu cccacaaucc gacggagacu     1500

caucuaaagu caaagucaaa gugcggguaa acauacaugg aauauucucc guugcaagug     1560

caagugugau agaaaaacaa aaccucgaag gggaucauuc agacgcaccu auggaaacgg     1620

aaacaaguuu caaaaacgaa aacaaagaua auauggacaa aaugcaagua gaucaagaag     1680

aaggacacca aaaaugccau gcggaacaua cucccgaaga agaaauagau cauacaggug     1740

cuaaaacaaa aucagcagua uccgacaaac aagacaggcu aaaucaaaca cucaagaaag     1800

gaaaaguaaa aaguauagac cugccgauac aaagcagucu cugucgacaa uuaggacaag     1860

auuuacuaaa uaguuacaua gaaaaugaag ggaaaaugau uaugcaagau aaauuagaaa     1920

aagaaaggaa cgaugccaaa aaugcuguug aagaauacgu auaugacuuu cgcgacagau     1980

uaggaacagu auacgaaaaa uuuauaaccc ccgaagaccu aaguaaacua ucugcaguac     2040

uagaagacac agaaaauugg uuauaugaag auggagaaga ucagccaaaa caaguuuacg     2100

uagauaaacu acaagagcuu aagaaauacg gacaaccaau ucaaaugaaa uauauggaac     2160

augaagaacg cccgaaagca uuaaacgacu uaggaaagaa aauacaauua guaaugaaag     2220

uaauagaggc cuacagaaac aaagaugaaa gguaugacca ccucgauccc acagaaaugg     2280

aaaaaguuga aaaaugcaua ucagacgcua ugucauggcu aaacagcaaa augaacgccc     2340

aaaacaaauu aucacuuacu caggauccug uaguaaaagu aagcgaaaua guagcgaaaa     2400

gcaaagaacu agacaacuuu uguaacccua uaaucuauaa accuaaaccc aaagcagaag     2460

uaccagagga uaaacccaaa gccaauucug aacauaaugg gccaauggau ggacaauccg     2520

gcacagaaac aaaaucggac aguaccaaag acucaucaca gcacacaaaa agcaguggag     2580

aaauggaagu ugacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  4874
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt12)

<400>  4874
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacucucac uaguagcagc gauguuauua cuuuuaagug      120

cugcacgagc agaggaagaa gauaaaaaag aagacguagg uacaguagua gguauagacc      180

uaggaacaac auacucaugu guaggaguau ucaagaaugg acgaguagaa auuauagcaa      240

augaucaagg caauagaaua acaccaaguu auguagcuuu cacacccgaa ggagaaagau      300

uaauagggga cgcagcuaaa aaccaauuaa caagcaaucc agagaacaca guauuugacg      360

caaaaagauu aaucggcaga acauggaaug accccucugu acaacaagau auuaaauuuc      420

uaccguuuaa agugguagaa aaaaaaacaa aaccuuauau acaaguagac auaggaggag      480

gacaaacgaa aacauucgcu ccagaagaaa uaagcgcaau gguuuuaacu aaaaugaaag      540

aaacagcgga agcauauuua ggaaaaaaag uaacucacgc uguaguaaca gucccagcau      600

acuuuaacga ugcucaaaga caagccacaa aagaugcagg aacaauugca ggcuuaaaug      660

uaaugagaau aauaaaugaa ccuacagcag ccgcaauagc guacggacua gacaaaagag      720

aaggcgaaaa aaacauacua guauuugauu uaggaggagg aacauucgau guaagucuac      780

uuacaauuga caacggaguc uuugaaguag uagccacaaa uggagauacg caucuaggag      840

gagaggacuu cgaccaaagg guuauggaac acuucauaaa auuauacaaa aaaaaaacag      900

gaaaagacgu uagaaaagac aauagagccg uacaaaaauu aagacgagag guagaaaaag      960

caaaaagagc auugucaagc caacaccaag caagaauaga aauagaauca uuuuaugaag     1020

gagaggacuu cagcgaaaca cuuacaagag caaaauuuga agaacugaau auggauuuau     1080

uuagaaguac aaugaaacca guucaaaaag ucuuagaaga uagugauuua aaaaaaagcg     1140

acauagauga aauaguacuc guaggaggau caacaaggau accaaaaaua caacaauuag     1200

uuaaagaguu uuuuaaugga aaagaaccau cacgaggaau aaauccagac gaagcaguag     1260

cauacggagc agcaguacag gcaggaguac uaagcggaga ucaagauaca ggagaucuag     1320

ucuuacuaga ugucugccca cuuacauuag gaaucgaaac cguaggaggg guaaugacaa     1380

aacuaauacc acguaacacg guugugccaa caaaaaaauc acagauauuc aguacagcgu     1440

cagacaauca gccaaccguc acuauaaaag uauacgaagg agaacgacca cuuacaaaag     1500

auaaccaucu acuaggaacc uucgauuuaa caggaauacc acccgcccca agaggaguac     1560

cacaaauaga aguuacauuc gaaauagacg uaaacgguau ucuuagagug acagcugaag     1620

acaaaggaac cggaaauaaa aauaaaauaa caauaacuaa cgaucaaaac cgacuaacuc     1680

cagaagaaau agaacgcaug guaaacgaug cagaaaaauu ugcagaagaa gacaaaaaac     1740

uaaaagaacg aaucgauacu agaaaugaac uagaaucaua cgcauauuca uuaaaaaauc     1800

aaauaggcga caaagaaaaa cuaggaggaa aauuaucaag ugaggauaaa gaaacuaugg     1860

aaaaagcggu cgaagaaaaa auagaguggu uagaaaguca ucaagacgcu gauauagaag     1920

auuuuaaagc aaaaaaaaaa gaauuagaag agauaguaca accaauaaua ucaaaacuau     1980

auggaagcgc cgguccucca ccaacaggcg aagaagacac agcugaaaaa gacgaauuau     2040

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  4875
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt12)

<400>  4875
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagccccaa gagaauuagc aguuggaaua gaccuaggua      120

caacauacuc auguguagga guuuuucaac aaggaagagu ugagauacua gcaaaugauc      180

aaggaaacag aacaacaccc agcuauguag cauucacuga cacagaaaga uuagucggag      240

acgccgcaaa aucacaagca gcucuaaacc cucauaauac aguuuuugau gcuaaaaggc      300

uuauagggag aaaauucgca gacacaacag uacaaucaga uaugaaacac uggcccuuuc      360

gaguaguauc agaaggagga aaaccgaaag uaagaguuug cuauagagga gaagauaaaa      420

cauuuuaccc agaagaaauc ucaucaaugg uucuuaguaa gaugaaagag acagcggaag      480

cauacuuagg acaaccgguc aaacacgccg uuauaacagu accugcauau uucaaugaca      540

gucaaagaca agcuacaaaa gaugcaggag caauagcagg auuaaaugua uuaagaauua      600

uuaaugaacc aacagccgca gcaauagcau acggacuaga ucguagagga gccggagaaa      660

gaaacgucuu aauauuugau uuaggagggg gaacauuuga uguaucaguu cuaucgauag      720

augcaggagu auuugaagua aaagcuacag caggagauac acauuuaggc ggggaagauu      780

uugauaacag auuaguaaau cacuucaugg aagaauuuag aagaaaacac gguaaggacu      840

uaucaggaaa uaaacgagca cucagaagac uuagaacagc cugugaacga gcaaaacgua      900

cuuugagcuc aaguacacaa gcuacuuuag aaauagacag uuuauucgaa gguguugauu      960

uuuacacaag uauuacuaga gcaagauuug aagaacuaug uucagauuua uuucguucaa     1020

cauuagaacc aguagaaaaa gcacuaagag augcaaaacu agauaaagcu caaauacaug     1080

auguggugcu aguaggaggu uccacaagga ucccaaaagu ccaaaaacua cuacaagauu     1140

ucuuuaaugg caaagaacuc aacaaaagua uaaaucccga ugaagcagua gcauauggug     1200

cagcaguaca agcagcaguu uuaaugggag auaaguguga aaaaguacaa gauuuacuau     1260

uacuagacgu agcaccccua ucacucggac uagaaacagc uggaggagua augacuacac     1320

uaauucaaag aaacgccaca aucccaacaa aacaaacaca aacauuuaca acauacucag     1380

auaaucaacc aggcguauuu auacagguuu acgaagguga acgagcaaug accaaagaca     1440

auaaucuacu cgguagauuc gaacuaagug gaauaccacc agccccaaga ggaguaccac     1500

aaauagaagu aacauuugau auagaugcaa augguauucu cagcguaacu gcaaccgacc     1560

guagcacagg aaaagcuaac aaaauaacua uaacgaauga uaaaggaaga cuaaguaaag     1620

aagaaguaga acgcauggua caugaagcag aacaauauaa agcagaagac gaagcacaaa     1680

gagauagagu ugcagcuaaa aacaguuuag aagcacaugu guuccaugua aaaggaucau     1740

uacaagaaga aucauuaaga gauaaaauuc cagaagaaga uagacgaaaa augcaagaua     1800

aaugcagaga aguacucgca uggcuagagc acaaucaauu agcagagaaa gaggaauaug     1860

aacaccagaa acgagaauua gaacaaauuu gucgaccaau auuuaguagg uuauacggag     1920

gaccaggagu cccaggaggu ucaucaugug gaacccaagc aagacaagga gaucccagua     1980

cagguccaau aauagaagaa guugacuaag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  4876
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt12)

<400>  4876
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcuccaa gagaacuagc uguaggaaua gauuuaggaa      120

caacauauag uuguguagga guauuucaac aaggaagagu ugaaauacua gcaaaugauc      180

aagggaauag gacaacacca ucauauguag cauuuacaga uacagaacga uuaguaggag      240

augcagcaaa aucacaggca gcucuaaacc cacauaauac aguauuugau gcaaaaagac      300

uaauagguag aaaauuugca gacacuacag uacaaagcga uaugaaacau uggccauuuc      360

aaguaguauc agaagguggc aaaccaaaag ucagaguaug uuauagagga gaagauaaaa      420

cuuuuuaucc cgaagaaaua ucaucaaugg uauuaaguaa aaugaaagaa acagcagaag      480

cauaucuagg acaaccagua aaacaugcgg uaauaacagu uccaacauau uuuucaaacu      540

cacaaagaca agcaacaaaa gaugccggug caaucgcagg acuuaaagua uuaccaauaa      600

uuaaugaagc aacagcagca gcaauagcau auggacuaga uagaagagga gcuggaaaaa      660

gaaauguauu aauauucgau uuaggaggug gaaccuuuga uguaucagua uuaagcauag      720

augcaggagu auuugaaguc aaagcaacag caggagauac acaucuagga ggggaagauu      780

ucgauaauag auuaguaaau cacuuuaugg aagaguuuag aagaaaacau ggaaaagauu      840

uaagcgguaa uaaaagagca uuaagaagac uaagaacagc augcgaaaga gcaaaaagaa      900

caccaucaag caguacgcaa gcaacauuag aaauagacuc auuauucgaa ggaguagacu      960

uuuauaaauc aauaacaaga gcgagauucg aagaauuaug cucagacuua uucagaagua     1020

cacuagaacc aguagaaaaa gcauuaagag augcaaaacu ugacaaagca caaauacaug     1080

auuucguacu aggaggagga uuacacaguc auccacaagg agcugaagua gcagcaggac     1140

uauuacaacg acaaggugca gaacaagaac aucaaccaua gggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  4877
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt12)

<400>  4877
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaaaagguc cggcaguagg aaucgauuua ggaacaacau      120

auaguugugu cggaguauuu caacauggaa aaguugaaau aauagcaaac gaucaaggca      180

auagaacuac accaucuuac guugcauuua cagauacaga aagauuaaua ggggacgcag      240

cuaaaaacca aguagcaaug aacccaacaa auacaguauu ugacgcaaaa cgacuaauag      300

gaagaagauu ugaugaugcc guuguacaau cugacaugaa acauuggccc uuuaugguag      360

uaaaugacgc aggaagacca aaaguccaag ucgaauacaa aggagaaaca aagagcuuuu      420

acccugaaga aguuucuagc augguccuaa caaaaaugaa agaaauugca gaagcguacc      480

uaggcaaaac cguaacaaac gcagucguga caguaccagc auauuuuaac gauucacaaa      540

gacaggcaac aaaagacgca ggaacaauug caggacucaa cguacuccga auaauaaaug      600

aaccaacugc ugcagcaauc gcauaugggu uagacaagaa aguaggagca gagcgcaaug      660

uacuaauauu ugaccuagga ggagguacgu ucgauguaag cauauuaaca auagaagaug      720

gcauauuuga aguaaaaucc acagcaggag acacacacuu aggaggagaa gauuuugaca      780

auagaauggu caaccauuuc auugcagagu ucaaaagaaa acacaagaaa gauauuucag      840

aaaauaaaag agcaguaaga agauuaagaa cagcuuguga aagagcuaaa agaacuuuau      900

caucaucaac acaagcuagc auagaaauug acaguuuaua ugaaggaaua gauuucuaua      960

cauccaucac gcgagcaagg uuugaagaau uaaaugcaga cuuauuucga ggaacacuug     1020

acccuguuga aaaagcccua cgagacgcua aacuagacaa aagccaaaua caugacauag     1080

uucuaguagg aggaagcacu agaauaccca aaauacaaaa gcuacugcaa gacuucuuca     1140

acggaaagga acucaacaaa agcauuaauc ccgaugaagc aguagcuuac ggagcugcag     1200

uacaagcugc aauauuaagu ggagacaaaa gcgaaaacgu acaagaucua cuauuacuag     1260

auguaacacc ucuaagccuc ggaauagaaa cggcaggagg agugaugaca guacucauaa     1320

aaagaaauac uacaauacca accaaacaaa cacaaacauu uacaacauac ucagacaauc     1380

aaccaggagu auuaauacaa guauacgaag gagaaagagc caugacaaaa gacaauaauc     1440

uccuaggaaa auucgaauua acaggaauac caccagcacc ucgcggagua ccacaaaucg     1500

aaguaaccuu ugacauugau gcgaacggca uauuaaaugu uucagccguc gacaagucua     1560

caggaaaaga gaacaagaua acaauaacua augauaaagg gcgauuaagc aaagaagaua     1620

uagaacgaau gguacaagaa gcagaaaaau auaaagcaga agaugaaaaa caaagagaua     1680

aaguaucuag caaaaauagc cuagaaaguu augcauucaa uaugaaagcc acaguugaag     1740

acgaaaaauu acaaggcaaa auaaaugacg aagauaaaca gaaaauauua gacaaaugua     1800

acgaaauaau aaacuggcug gauaaaaauc aaacggccga aaaagaagaa uuugaacauc     1860

aacaaaaaga auuagaaaaa guaugcaauc cgauaauaac aaaauuauac caaucagcug     1920

gggguaugcc aggggguaug ccagguggau ucccaggagg gggagcacca ccaagcggag     1980

gagcaagcuc aggaccaaca aucgaagaag ucgacuaagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  4878
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt12)

<400>  4878
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auauccgcau caagagcagc agcggcaaga uuaguaggag      120

cagcagcaag uagaggacca acagcagcaa gacaccaaga caguuggaau gguuuaagcc      180

augaagcauu uagacucgug aguaggagag auuaugcaag ugaagccaua aaaggagcug      240

ugguaggaau agauuuagga acaacuaauu cauguguugc aguaauggaa ggaaaacagg      300

cuaaaguacu agagaaugcg gaaggagcua gaaccacucc caguguagua gcauucacag      360

cugauggaga aagauuggua gggaugccgg caaaaagaca agcaguuacg aacccaaaua      420

acacauuuua ugcaacaaaa cgacuaauag ggaggcgaua cgaugacccg gaaguucaaa      480

aagauauuaa aaacguuccu uuuaagauag uaagagccag caauggagau gccuggguag      540

aagcccacgg aaaguuauau ucaccaaguc aaauaggggc uuuuguacua augaaaauga      600

aagaaacagc cgaaaauuac uuaggacaua cugcuaaaaa ugcaguuaua acaguaccag      660

cauauuuuaa ugauagccaa agacaagcua caaaagaugc aggucagaua aguggucuca      720

acguucugcg cguaauuaau gaaccaacag cugcugcacu agcauacggg uuagauaaaa      780

gugaagauaa agucauagcg guauaugauu uaggaggagg cacauuugau auaucaauau      840

uagaaauaca aaaaggggua uucgaaguua aaagcaccaa uggagauacg uuucuuggag      900

gggaagauuu ugaccaagcg uuauuaagac auauagugaa agaauuuaag agagagacag      960

gaguagaucu aacaaaagac aacauggcau uacaaagagu uagagaagcu gcugagaagg     1020

caaaauguga auuaagcuca aguguacaaa cagauauaaa uuuacccuau uuaacaaugg     1080

auagcagugg accgaaacau cuaaauauga aauugaccag agcucaauuu gaaggaauag     1140

ugacagauuu aauaaggaga acaauagcac caugccagaa agcaaugcaa gaugcagagg     1200

ugaguaaaag cgauaucgga gaagugauau ugguaggagg aaugacaaga augccaaaag     1260

uacaacaaac aguacaagac uuauuuggca gagcaccaag caaagcuguu aacccagaug     1320

aagcaguggc uauuggagca gcuauacaag gaggaguguu agcaggagau guaacagaug     1380

uauuauuacu agauguaaca ccauuaucau uggguauaga aacacuagga gggguauuua     1440

caaagcuaau aaauagaaau acaacaauac caacaaagaa gucucaagua uucucaacug     1500

cagcagaugg gcaaacacaa guagaaauaa aaguauguca aggagaaaga gaaauggcag     1560

gcgacaauaa acuacuugga caauuuacac uaauaggcau accgcccgcc cccaggggag     1620

uuccacaaau agaaguaacc uucgauauag augccaacgg aauaguacac guaagcgcaa     1680

aggacaaagg gacagggaga gaacaacaaa uaguaauaca auccagcgga gguuuaucaa     1740

aagacgacau agaaaacaug guuaaaaaug cagagaagua ugcagaagaa gauagaagaa     1800

agaaagaaag aguagaagca guaaauaugg cagaggguau uauacaugau acggaaacaa     1860

aaauggaaga auuuaaagau caauuaccug cagacgaaug caauaaacua aaagaagaaa     1920

uaagcaaaau gagagaauua cuagcaagaa aagauucgga aacuggagaa aauauaagac     1980

aagcagcuag uagccugcag caagccagcu uaaaacuauu cgagauggca uauaagaaaa     2040

uggcaagcga aagagaaggc agugggagcu caggaacagg ugaacaaaaa gaagaccaaa     2100

aagaagaaaa acaauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  4879
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt12)

<400>  4879
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcugauaaag aagcuggagg uucugaugga ccacgagaaa      120

cagcuccaac uucugcuuac ucaaguccag caaggucuuu aggagacacg ggaauuaccc      180

cguuaagucc cagucauaua gucaacgaua cugauucuaa cguguccgaa caacaaagcu      240

uucuuguagu aguagcaguu gacuucggaa cuacuucauc aggauaugcg uauucauuua      300

caaaagaacc agaauguauc cacgugauga gacgauggga aggaggagau cccggaguaa      360

gcaaucaaaa aacaccgaca acaauacucu uaacaccaga acgaaaauuc cauucauuug      420

gcuacgcagc uagagauuuc uaucaugauc uagauccaaa ugaagcaaaa caaugguuau      480

aucuugaaaa auuuaaaaug aaacuacaua caacagguga ccucacaaug gauacugauc      540

uaacagcagc aaaugggaag aaaguuaaag cacuagaaau auuugcauac gcccuucaau      600

acuuuaaaga acaagcacuu aaagaacuau cagaucaagc aggaucugaa uuugaaaaua      660

gcgauguuag auggguaaua acaguuccag caauauggaa acaaccagca aaacaauuua      720

ugcgccaagc ugcauaccaa gcaggacucg ccucuccaga gaauucagaa caauuaauaa      780

uugcauuaga accugaagca gccaguauau auugcagaaa acuaagauua caucaaauga      840

uugaauuaag uaguaaagca gcaguaaacg guuauagugg uucagauaca guaggagcug      900

gcuuuacuca agcaaaagaa cauauaagaa gaaauagaca aucaaggaca uuuuuaguag      960

aaaauguaau uggugaaaua ugguccgaau uagaagaagg agacaaauau guagucguag     1020

acucuggugg cggaacugua gaccuaacag uacaucaaau aagacuucca gaaggacauc     1080

uaaaagaauu auauaaagca acgggaggcc ccuauggauc auuaggugua gauuaugaau     1140

ucgaaaaauu auuauauaaa auauuuggcg aagauuuuau agaacaauuc aaaauaaaaa     1200

gaccugcggc uuggguagac uuaaugauag cuuuugaauc aagaaaaaga gcugccgccc     1260

cagacagaac aaauccauua aauauaacau uaccauuuuc auuuauugau uauuauaaaa     1320

aauuuagagg acacucugua gaacaugcac uuagaaaaag caacguagau uuuguaaaau     1380

ggaguucuca aggaauguua agaaugucac cagacgcaau gaacgccuug uucaaaccaa     1440

cgauugauag uauaauagaa cacuuacgcg acuuauuuca aaaaccagaa guaucaacag     1500

ucaaauuucu auuuuuaguc ggaggauuug cagaagcacc acuucuacaa caagcaguac     1560

aagcagcauu uggagaucaa ugcagaauca uaauaccuca agacguaggc cucacgauuc     1620

uaaaaggcgc agugcuauuc ggucuagauc cagcaguuau aaaaguucgg cgaucacccu     1680

uaacauaugg aguuggagua uuaaaucgau acguagaagg aaaacaucca ccagaaaaau     1740

uauuaguaaa agacgguacg agauggugua ccgauguauu cgauaaauuu auaucagcag     1800

accaaucagu agcucucggc gaacucguua aaagauccua uacaccagca aaaccaucuc     1860

aauuaguuau aguaauuaau auauauucaa gcgagcacga uaacguuuca uuuauaacag     1920

auccaggugu aaaaaagugc gguacauuaa gacucgacuu aaccggaaca aguggaacag     1980

caguuccagc acgcagagaa auacaaacau uaaugcaauu uggugauacu gaaauaaaag     2040

caacagccau agacauagcc acaucaaaau caguuaaagu uggaauagac uuucuaaauu     2100

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  4880
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt12)

<400>  4880
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuagcaguac cagaaauggg auuacaggga cuauauauug      120

gaucuucucc agaaagauca ccaguaccau caccacccgg gucaccaaga acccaagaaa      180

gcuguggaau agcuccacua acaccaucac aauccccuaa accagaagua agggcacccc      240

aacaagccag uuucaguguu guaguagcaa uagauuuugg aacuacauca ucagguuacg      300

cauuuuccuu ugcaucagau ccugaagcaa uucauaugau gagaaaaugg gaaggaggag      360

acccuggcgu agcacaucag aaaacuccua cauguuuacu uuugacacca gaaggagcau      420

uucauucauu uggauauaca gcacgagauu auuaucacga cuuagaucca gaagaagcua      480

gagauuggcu cuacuuugaa aaauuuaaaa ugaaaauaca uagugcaaca gaucuaacau      540

uaaaaaccca auuagaagcu guuaauggua aaacuaugcc agcgcuagaa guauuugcgc      600

acgcauuaag auuuuuccga gaacaugcau uacaagaacu uagagaacaa ucaccuucac      660

uaccugaaaa agauacaguu agauggguau ugacuguacc ggcaauaugg aaacaaccag      720

cgaaacaauu uaugagagaa gcugcauauu uagcuggguu aguaucacga gaaaaugcag      780

agcaacucuu aauugcgcuu gagccagaag cagcaucugu cuacugcaga aaauuaagac      840

uacaucaacu acuagauuua aguggcagag cacccggagg uggaagacua ggugagcgaa      900

gaagcauaga uucaaguuuc cgacaagcaa gagagcaacu aagacgauca agacacucaa      960

gaacauuucu aguagaaagc gguguaggag aauuaugggc agaaaugcaa gcaggagauc     1020

gauauguagu ugccgauugc ggggguggca caguagauuu aacaguccau caacuagaac     1080

aaccacacgg aacucuaaaa gaacuauaua aagcaucagg agguccauac ggcgcaguag     1140

gaguggacuu agcguucgaa caacuacuau gcagaauauu uggagaagau uuuauagcga     1200

cauuuaaaag acaaagaccu gcggccuggg uagaucuaac aauagcauuc gaagcaagaa     1260

aacggacggc cgggccgcau agagcaggag cucuaaauau aagccuacca uuuucauuua     1320

uagacuuuua uagaaaacag agaggacaua acguugaaac ugcacugaga cgauccucag     1380

uaaauuucgu aaaauggucu ucacaaggaa uguugcgaau gagcugcgaa gcaaugaaug     1440

aacuauuuca accaacugua aguggcauua uucaacauau agaagcacua uuagcaagac     1500

cugaagucca aggaguuaaa cugcuauucc ugguaggugg auuugcagaa ucggcaguau     1560

uacagcaugc aguacaagca gcuuuaggug caagaggauu acgaguagua guaccacaug     1620

auguaggacu aacaauuuua aaaggagcug uacuauucgg ccaagcucca ggaguuguaa     1680

gaguuagaag aaguccauua accuacgggg uagggguacu uaauagauuc guaccuggac     1740

gacauccacc agaaaaauua uuaguaaggg auggaagacg cugguguaca gauguguucg     1800

aaagauucgu agcugcugaa cagagcguug cucuagggga agaaguacga agaucauacu     1860

guccagcuag accaggccaa aggcgaguau uaauaaauuu auauuguugu gcagcagaag     1920

augcaagauu caucacugau ccaggaguua gaaaaugcgg agcacucucu cuagaguuag     1980

aaccugcgga cuguggacaa gacaccgcag gagccccacc aggaaggaga gaaauacgag     2040

cagcaaugca auuuggugau acagaaauua aagucacugc aguagaugua ucgacaaaua     2100

gaucaguaag agcuucgauu gauuuccuuu cgaauuaagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  4881
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt12)

<400>  4881
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucgagaaa ugacaauuuu aggaucagcg guauugacac      120

uuuuauuagc aggauaccua gcccaacaau accuaccacu accuacacca aaagugauag      180

gaauagaccu uggaacaaca uacuguucag uaggaguauu cuuuccagga acagguaaag      240

uaaaaguaau accagaugaa aacggacaca uaaguauacc cucaauggua aguuuuaccg      300

auaacgaugu auacguagga uacgaaucag uugaauuagc agacucaaau ccacaaaaca      360

caauauauga cgcaaaaaga uuuaucggaa aaaucuucac agcagaggaa uuagaagcag      420

aaauaggaag auaucccuuc aaaguauuaa auaaaaacgg aaugguagaa uucucuguca      480

caucaaacga aacaauaaca guaagcccag aauacguagg cagucgauua cuacuaaaac      540

ucaaagaaau ggcagaagcg uacuuaggaa ugccaguagc aaaugccgua auaucagucc      600

cagcagaauu cgaucuaaaa caacgaaaca gcaccauaga agcagccaau cuagcaggau      660

uaaaaauacu aagaguaaua aacgaaccaa ccgcagcagc cauggcauau ggacuacaca      720

aagcagaugu auuucacgua uuaguaauug aucuaggagg cggaaccuua gacguaucau      780

uauuaaauaa acaaggagga auguucuuaa cuagagccau gucaggaaau aacaaacuag      840

gaggacaaga uuuuaaccaa cgacucuuac aauacuuaua caaacaaaua uaucaaacau      900

auggauuugu uccuagcaga aaagaagaaa uacauagacu aagacaagcc guagaaaugg      960

uuaaauuaaa ucuuacacuc caccaaagug cacaacuaag cguguuacua acaguagaag     1020

aacaagacag aaaagaacca cacucuucag acacagaauu accaaaggau aaauuaucau     1080

cagcagauga ccaccgagua aauucaggau ucggaagagg acuaucagau aaaaaaucag     1140

gagaaucaca aguucuauuc gaaacagaaa uaucaagaaa acuauuugac acauuaaacg     1200

aagauuuauu ccaaaaaaua cuaguaccaa uacaacaagu acuuaaagaa ggacaucuug     1260

aaaaaacgga aauagacgaa guaguacucg uaggagguuc aacaagaaua ccaagaauaa     1320

gacaaguaau ucaagaauuu uuuggaaaag acccaaauac auccguagau ccagaucuag     1380

ccguaguaac cggcguagcu auacaagcag gaauagaugg uggaucaugg ccauuacaag     1440

uaucagcacu cgaaauccca aacaagcacu uacaaaaaac aaauuucaac uaaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4882
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt12)

<400>  4882
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagcaaucg gaguucaucu aggauguaca agcgcaugcg      120

uagcaguaua caaagacggu cgagcaggug uugucgcaaa cgaugcagga gauagaguaa      180

caccagcugu aguagcauau agugaaaacg aagaaauagu aggauuagca gcaaaacaaa      240

gcaggauucg aaauauauca aauacaguaa ugaaaguaaa acaaauauua ggccgaagca      300

gcuccgaccc ucaagcacaa aaauauauag cagaaaguaa auguuuagua auagaaaaaa      360

auggaaaacu aagauacgaa auugauacgg gagaagaaac aaaauucgua aauccggaag      420

auguagcaag gcuaauauuu agcaaaauga aagaaacagc ucauagugua uuaggaagcg      480

acgcaaacga cguaguuaua acagucccuu ucgauuuugg agaaaaacaa aaaaaugcuc      540

uuggagaagc cgcaagagca gccggcuuua auguacuaag acuaauacau gaaccaucag      600

cagcucuauu agcauaugga aucggacaag auucaccaac agguaaaagu aacauacuag      660

uauuuaaauu aggaggaaca ucauuaucac uauccguaau ggaaguaaau ucaggaaucu      720

auagaguauu aaguacaaac acagacgaca acauuggagg agcacacuuu acagaaacuu      780

uagcacaaua ucuugcaucc gaauuucaaa gaaguuuuaa acaugacgua agagguaacg      840

caagagcgau gaugaaacug acaaauucag cagaaguagc aaaacauagu cuaucaacau      900

uaggauccgc aaacugcuuu cuagauaguu uauaugaagg acaagacuuu gacugcaaug      960

uaucaagagc acguuucgaa cucuuauguu caccguuauu uaauaaaugc auagaagcaa     1020

uaagaggacu auuagaucaa aauggauuua cagcugauga uauaaauaaa guuguguuau     1080

guggaggauc aucaagaaua ccaaaauuac aacaauuaau aaaagauuua uuucccgcag     1140

uagaauuauu aaauucaaua ccaccagacg aaguaauucc aauaggcgca gccaucgaag     1200

caggcauacu aauaggaaaa gaaaaccuau uaguagaaga cucauuaaug auagaauguu     1260

cagcaagaga uauauuagua aaaggaguag augaaagugg ugcgucaagg uuuacaguau     1320

uauuuccaag cggaacacca cuaccugcaa gaagacaaca uacgcuacaa gcaccaggua     1380

guauaaguuc aguaugucua gaacuauaug aauccgacgg aaaaaacagc gcaaaagaag     1440

aaacaaaauu ugcacaaguu guuuuacaag auuuagauaa aaaagaaaac ggcuuaagag     1500

acauuuuagc aguauuaaca augaaacgcg auggaucacu acauguaaca uguacagacc     1560

aagaaacagg aaaaugcgaa gcaauaagua uagaaauagc uucauaagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  4883
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt12)

<400>  4883
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaguaguag gacuugaugu aggaucacaa ucauguuaca      120

uagcaguagc uagagccggu gggauagaaa caauagcaaa cgaauuuagu gauagaugca      180

caccaagugu cauaucauuu gguagcaaaa acagaacaau aggaguagca gcgaaaaacc      240

aacaaauaac ccacgcaaac aacacaguau caaacuucaa aagauuccac ggcagagcau      300

uuaacgaccc cuucauacaa aaagaaaagg aaaacuugag uuaugacuua guaccacuca      360

aaaauggagg aguuggaaua aaaguaaugu acauggggga agaacacuua uuuagcguag      420

aacaaauuac ugcaaugcua uuaacaaaac uuaaagaaac agcagaaaac ucauuaaaga      480

aaccaguaac agauugugua aucuccguac caucuuucuu uacagaugca gaaagacgau      540

ccgucuuaga cgcagcacaa auaguuggcc uaaauuguuu aagguugaug aacgacauga      600

cugccguagc ccuaaauuau gguauuuaca aacaagacuu accaagccuc gaugagaaac      660

cccggauagu aguauuugua gacaugggac acagcgcauu ucaagugagu gccugugccu      720

uuaacaaagg aaaacucaaa guucucggua ccgccuuuga uccguuuuua ggaggcaaaa      780

auuucgacga aaaauuaguc gaacauuuuu gcgcagaauu uaaaacaaaa uauaaauuag      840

acgcgaaaag caaaauaaga gcgcuacuga gauuauacca agaaugugaa aaacuaaaga      900

aacuaaugag uucaaauagu acagaccuac cacuaaauau agaguguuuc augaacgaca      960

aagacguaag cggaaaaaug aauagaucac aguucgaaga acuuugugca gaacuauuac     1020

agaaaauaga aguucccuua uauucauuau uagaacaaac acacuuaaaa guagaggaug     1080

ucucagcugu agaaaucguc ggaggagcca cccguauucc agcggucaaa gaaagaauag     1140

caaaauucuu uggcaaagac auaaguacaa cccuaaacgc cgaugaagca gucgcaagag     1200

gaugugcacu ccaaugugca auccuuaguc cagccuuuaa aguaagagag uuuuccguaa     1260

cugacgcagu accauuuccu auuucucuaa uuuggaauca ugauucagaa gauacagaag     1320

gaguacauga aguauuuuca agaaaccaug cagcaccguu caguaaagua uugacauuuu     1380

ugcgaagagg cccauucgaa cuagaagcau uuuacucaga uccacaaggg guaccauacc     1440

ccgaagcaaa aaucggaaga uuuguuguac aaaacgucuc agcacaaaaa gauggagaga     1500

aaagcagagu aaaaguaaaa guacgaguaa acacucaugg aauauucaca auaucuaccg     1560

caagcauggu agaaaaaguc ccaacagaag aaaacgaaau gucaagcgaa gccgauaugg     1620

aaugcuugaa ucaacgaccg cccgaaaacc cagauacuga caaaaacgua caacaagaua     1680

auucagaagc uggaacucaa ccacagguac aaaccgaugc acaacaaacc ucacaaagcc     1740

caccaagucc cgaacuuacg uccgaagaaa acaaaauacc agacgcagau aaagcaaacg     1800

agaagaaagu cgaccaacca ccagaagcaa agaaaccgaa aauaaaagua gugaauguag     1860

aauuaccaau agaagccaac cuaguguggc aacuaggaaa agaccuccua aacauguaca     1920

uugaaacaga aggaaaaaug auaaugcaag auaaauugga gaaagaaaga aacgacgcca     1980

aaaaugcagu agaagaauac gucuacgagu ucagagauaa acuauguggu ccauaugaaa     2040

aauucauaug ugaacaagau caccaaaauu uccuuagauu acuuacagaa acugaagauu     2100

gguuauauga agaaggcgaa gaucaagcaa aacaagccua cgucgacaaa uuagaagaau     2160

uaaugaaaau aggaacacca gugaaaguaa gauuccaaga agcagaagaa agaccaaaaa     2220

uguuugaaga auuaggucag cgcuuacaac auuacgccaa aauugcagca gauuuuagaa     2280

auaaagauga aaaauauaac cauauugacg aaucagagau gaagaaagua gaaaaaucag     2340

ucaaugaagu aauggaaugg augaauaaug uaaugaacgc ucaagcaaag aaaucauuag     2400

accaagaccc aguagugaga gcccaagaaa uaaaaacaaa aauaaaagaa uuaaauaaua     2460

caugugaacc uguuguuaca caaccaaaac caaaaauaga aaguccaaaa cuagaacgaa     2520

cgccaaacgg accaaauaua gacaagaaag aagaagaucu agaagacaaa aauaacuucg     2580

gugcagaacc uccacaucaa aacggagaau guuacccaaa cgagaaaaac aguguaaaca     2640

uggacuuaga cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  4884
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt12)

<400>  4884
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgauaaag uaaggcgcca acguccaaga agaagaguau      120

guugggcacu uguugcaguu cuacuugcag acuuauuagc acuaagugau acacuugcag      180

ugaugagugu agaucuugga uccgaaagca ugaaaguagc aaucguaaaa cccggaguac      240

caauggaaau uguacucaac aaagaaaguc gaagaaaaac accaguaauc guaacucuaa      300

aagaaaauga aagauuuuuc ggggauucug cagcaucuau ggcaauuaaa aacccaaaag      360

cuacauuacg uuacuuccaa cauuuacuug guaagcaagc agauaacccu cacguugcuc      420

uauaucaggc ucguuuccca gaacaugaac ucacauucga cccacaacga cagacaguac      480

acuuucaaau aucaagccaa uuacaauucu caccagaaga aguacuaggu augguacuaa      540

acuauucgcg aaguuuagca gaagacuucg cugaacaacc aauaaaagau gccguaauaa      600

cagucccagu cuucuuuaac caagcagaaa ggagagccgu ucuacaagcg gcuagaaugg      660

caggauuaaa aguauugcaa cuaauaaaug acaauacugc gaccgcccua aguuacggcg      720

uuuuucgaag aaaagauaua aauacaacag cccaaaacau aauguucuac gacaugggaa      780

guggaucaac aguaugcacu auaguuacau accaaauggu aaaaacgaag gaagcaggaa      840

ugcaaccaca gcuacaaaua agaggaguag gauuugaucg uacacuagga ggauuagaaa      900

uggaacuaag acuuagagaa cgcuuagcag gauuguucaa ugaacaaaga aagggccaac      960

gcgccaagga ugugagagag aauccaagag caauggcaaa auuacucaga gaggccaacc     1020

gguuaaaaac aguguuauca gcaaacgcag aucauauggc ucagauagaa ggacugaugg     1080

augacguuga uuucaaagca aaagucacac gaguugaauu ugaagaguua ugugcagauu     1140

uauucgaaag aguuccugga ccuguucaac aagcgcuaca aagugcagaa augaguuuag     1200

augagauuga acaagugauu cuaguuggcg gagcaacucg aguuccaaga guccaagaag     1260

uacuguuaaa agccguaggc aaagaagaau uagguaaaaa uauaaaugcc gaugaagcag     1320

ccgcaauggg agccguuuau caagcugcug ccuuaucgaa agcauuuaaa guaaaaccau     1380

uuguuguaag ggacgccgug guauacccaa uauuagucga guuuacacga gaagucgaag     1440

aagaacccgg aauacauuca uuaaaacaua acaaacgagu ucuauuuuca agaauggggc     1500

cguauccaca aagaaaagua auaaccuuua auagauacuc ccacgauuuu aauuuccaca     1560

uuaauuaugg agaucuagga uuuuuagguc cggaagaucu ucguguauuu gggucacaaa     1620

auuugacaac agucaaacua aaaggagucg gagacucauu uaagaaauau ccagauuaug     1680

aaucaaaagg aauuaaagcu cauuucaauu uggaugaaag uggaguacuc agucuagaua     1740

ggguagaaag cguauuugaa acauuagucg aagacucagc agaagaagaa agcacucuga     1800

cuaaacuagg aaauacaaua ucaucacuau ucggaggugg gacgacccca gaugcaaaag     1860

aaaauggaac agauacugua caggaagaag aagaaucacc agcagaagga agcaaggaug     1920

aaccagguga gcaaguagaa cuaaaagaag aagcagaagc accaguagaa gacggaaguc     1980

aaccaccucc accagaaccu aaaggagacg cgaccccaga aggagaaaaa gcuacagaaa     2040

aggaaaaugg agauaaauca gaagcucaaa aaccgucaga aaaagcugaa gcaggaccag     2100

aaggcguugc cccagcaccg gagggagaaa agaaacaaaa accagcaaga aaaagaagaa     2160

ugguggaaga aaucggugua gagcuaguag uauuagacuu accugacuua ccagaagaua     2220

aauuggcuca auccguucaa aaacuucaag aucuaacacu uagagacuua gaaaaacaag     2280

aacgagaaaa agcagcaaac ucacuagaag cauuuauauu cgaaacacag gauaaacuau     2340

accaaccaga auaccaagag guuucaacug aggaacaaag ggaagagauc ucaggaaaac     2400

ucagugcagc caguacaugg uuggaagacg aaggaguagg cgcaacaacg gucauguuaa     2460

aagaaaaacu agcggaacuu agaaaauuau gccaaggauu auuuuucaga guugaagaaa     2520

gaaagaaaug gccagaaaga uuauccgcuu uggauaauuu auuaaaucau ucaucaaugu     2580

uucuaaaagg cgcaagauua auaccugaaa uggaucaaau auucacagaa guagaaauga     2640

cuacauuaga aaaaguaaua aaugaaacuu gggcuuggaa aaaugcuaca cuagcagaac     2700

aagcaaaauu accagcuacc gaaaaaccag uacuacuauc aaaagacaua gaggcaaaaa     2760

ugauggcccu agacagagaa guucaauauc uacuaaauaa agcaaaauuu acuaaaccua     2820

gaccaagacc uaaagauaaa aaugguacac gagcugagcc uccacucaau gcguccgcau     2880

ccgaucaagg agaaaaaguu auacccccug ccggacaaac agaagacgca gagccaaucu     2940

cagaaccaga aaaaguggaa acaggaagug aaccuggaga cacagaacca cuagaacucg     3000

gagguccggg ggcagaacca gaacaaaaag aacagaguac aggacaaaaa cgaccgcuaa     3060

agaaugauga guuauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4885
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt12)

<400>  4885
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaggaaa cccaaacuca agaucaacca auggaagaag      120

aagaaguaga aacauuugcu uuccaagccg aaauagcaca acugauguca cuaauaauaa      180

auacauuuua uucaaacaag gaaauuuucu ugagagaacu cauaaguaac ucaagcgacg      240

cacucgacaa aauaagauac gaaagccuaa cagacccguc uaaacuggac ucaggaaaag      300

agcuacauau aaaccuaaua ccuaacaaac aagauagaac acuaaccaua guagauacag      360

gaauagguau gacaaaagca gauuuaauaa acaaccuagg cacaauagcc aaguccggaa      420

ccaaagcguu cauggaagcg cuccaagccg gcgcagauau cagcaugaua ggacaauucg      480

ggguaggauu cuacucagca uaucuaguag cagaaaaagu aacgguuauc accaaacaua      540

augacgacga acaguacgca ugggaaaguu cggcaggcgg cucauucaca gucagaaccg      600

acaccgggga accaauggga agagguacaa agguaauacu acaccuuaaa gaagaccaaa      660

cagaauaccu agaagaaagg agaauaaaag aaauaguaaa aaaacacuca caauucauug      720

gauacccaau aacauuauuu guagaaaaag aaagagacaa agaaguaagc gacgaugaag      780

cagaagaaaa agaagauaaa gaagaagaga aagaaaaaga agagaaagaa agugaagaca      840

aaccagaaau agaagacguu ggcucggaug aagaagaaga aaaaaaagac ggagauaaaa      900

aaaaaaaaaa aaaaauaaaa gaaaaguaca uagaucaaga agaacucaau aaaacaaagc      960

caauauggac acgaaaucca gaugacauaa cuaacgaaga auacggcgaa uuuuauaaaa     1020

guuuaacaaa cgacugggaa gaccaucucg caguaaaaca uuuuucagua gaaggacaac     1080

uagaauucag agcacuauua uucgucccca gaagagcacc auuugauuua uuugaaaaua     1140

gaaaaaaaaa aaacaacauu aaacuauaug uaagaagagu uuucauaaug gacaauugug     1200

aagaauuaau accagaauau cuaaacuuua uaagaggggu gguugacagc gaagauuuac     1260

cgcuuaacau aagccgagaa auguugcaac agaguaaaau acuaaaagua auaagaaaaa     1320

aucuaguaaa aaaauguuua gaauuauuua cggaauuagc agaggacaaa gaaaacuaca     1380

agaaauuuua cgaacaauuc aguaaaaaca uaaaauuagg cauacacgaa gacagucaaa     1440

auagaaagaa acuaucagaa cuacuaagau auuacacaag ugcaagugga gaugaaaugg     1500

uaagcuuaaa agacuacugu acaagaauga aggaaaacca aaaacauaua uauuauauaa     1560

caggagaaac aaaagaucaa guagcaaaca gugccuucgu agaaagacua agaaaacaug     1620

ggcuagaagu aauauacaug auagaaccua uagaugaaua uugcguacaa caacuaaaag     1680

aauuugaagg aaaaacccua guaucgguaa caaaggaagg auuagaauua cccgaagaug     1740

aagaagaaaa aaagaaacaa gaagaaaaaa aaacaaaauu cgaaaaccua ugcaaaauaa     1800

ugaaagauau acuagaaaaa aaaguugaaa aaguuguggu aucuaacaga uuaguaacuu     1860

caccaugcug caucguaacu aguacguaug gcuggacagc aaacauggaa agaauaauga     1920

aagcacaggc uuugagagau aacaguacca ugggauauau ggcagcaaaa aaacaucuag     1980

aaauuaaucc agaccacagu auaauagaaa cguuaagaca gaaagcagaa gcggacaaga     2040

acgacaaauc aguaaaagac cucguuauac uacucuauga aacagcacua cuaagcagug     2100

gauuuucauu agaagaucca cagacacacg caaacaggau uuauagaaug auuaaacuug     2160

gacucggaau agacgaagau gacccaacag cagaugacac aagugcagca gugaccgaag     2220

aaaugccacc guuagaaggg gaugacgaca cuaguagaau ggaagaagua gauuaaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  4886
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt12)

<400>  4886
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucaa aacuagacuc aggaaaagga cuacacauaa      120

accuaguacc aaacaaacaa aaccaaacac uaacaauagu agacacaaga auaggaauga      180

caaaaacaga ccuaauaaac aaccuaggaa caguaacaaa aagcggaaca aaagcauuua      240

uggaagcacu acaagcagac gcagacauaa gcaugauagg acacuucgga guaggauucu      300

acucagcaua ccuaguagca aaaaaaguaa caguaauauc aaaacacaac aacgacgaac      360

aauacacaug ggaaucaagc gcaggaggaa gcuucacagu aagaacagac gaauaaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  4887
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt12)

<400>  4887
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaagaag uacaccaugg agaagaagag guagaaacau      120

ucgcauuuca agcagagauu gcacaacuaa ugaguuugau aauaaauaca uuuuauagca      180

acaaagaaau auuuuuaaga gaacuaauuu cuaacgcaag cgacgcauua gacaaaauac      240

gauaugagag ucuaacugau ccaaguaaac uagauagugg aaaggaacuu aaaauagaca      300

uaauaccgaa uccacaagaa cgaacauuga cacuagugga cacaggcaua ggaaugacaa      360

aggccgaucu aauaaauaau cuuggcacaa uagcaaaaag ugggacuaaa gcguuuaugg      420

aggcacuaca agcgggagca gauauaagua ugauaggaca auuuggaguu ggauuuuauu      480

cagcauacuu aguggcagaa aaaguugucg uaauaacaaa acauaacgau gacgaacaau      540

acgccuggga aucaagcgca ggaggaaguu uuacaguaag agcagaccac ggugaaccaa      600

ucggaagggg aacaaaagua auacuacacu uaaaagaaga ucaaacagag uauuuggaag      660

aacgaagggu aaaagaagua guaaaaaaac acucacaauu uauaggauau ccgauaacau      720

uguaccuaga aaaggaaagg gaaaaagaaa uaagcgauga cgaagcagaa gaagaaaaag      780

gggaaaagga agaagaagau aaagacgaug aagaaaaacc aaaaauagag gacguaggaa      840

gugaugaaga agaugacuca ggaaaagaua aaaaaaaaaa aacuaaaaaa aucaaagaaa      900

aauacauaga ucaagaagaa uuaaauaaaa caaagccaau auggaccaga aacccagacg      960

acauaacaca agaagaauau ggcgaauucu auaaaagucu aacaaaugac ugggaagacc     1020

accuagcagu aaaacacuuc agcgucgaag gucaauuaga auucagagcu cuacuauuua     1080

uaccaagaag agcaccauuc gaucuauucg aaaacaaaaa aaaaaaaaau aauauaaaac     1140

ucuacguccg cagagucuuu auaauggacu cgugcgacga acuaauccca gaauauuuaa     1200

acuuuaucag agggguagua gacucagagg accucccacu aaacauaagc agggaaaugc     1260

uucaacaaag caaaauccua aagguaauca gaaaaaauau cgucaaaaaa ugccucgaac     1320

uauuuucaga auuagccgaa gauaaagaaa acuacaaaaa auuuuacgaa gcauucagca     1380

aaaauuuaaa acuaggcaua cacgaagacu ccacaaacag aagaagauua agcgaauuac     1440

uaagauauca cacaucacag ucgggagaug aaaugacauc uuuaucagag uacguaagcc     1500

gaaugaaaga aacacaaaaa aguauauacu auaucacugg agaaaguaaa gaacaaguag     1560

cgaacucagc auuuguagaa cguguaagaa aacgaggauu ugaaguagua uacaugacag     1620

aaccaauuga cgaauacugu guccaacaau uaaaagaauu cgaugguaaa aguuuaguuu     1680

caguaacaaa agaaggauua gaauuaccug aagacgaaga agaaaagaaa aaaauggaag     1740

aaagcaaagc aaaauuugaa aaucuaugca aacucaugaa agaaauauua gacaaaaaag     1800

uggaaaaagu cacgauuucc aacagacucg uaagcucacc cuguugcaua guaacaucua     1860

cauaugguug gacugcaaac auggaaagaa uaaugaaagc acaagcuuug agagacaauu     1920

caacaauggg auauaugaug gcaaagaaac auuuagaaau aaacccagac cauccaaucg     1980

uagaaacacu gagacaaaag gcagaagcag acaaaaauga uaaggccgug aaagaucuug     2040

ugguacuucu auucgaaaca gcccuacuga guaguggauu caguuuagaa gacccacaaa     2100

cacacuccaa uagaaucuau cgaaugauca aacuaggauu aggaauagac gaggaugaag     2160

uagcugcaga agaaccaaau gcagcaguac cagaugaaau accaccgcua gaaggagaug     2220

aagaugcgag ccgcauggaa gaaguagacu agggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  4888
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt12)

<400>  4888
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agagcacugu ggguauuagg auuaugcugc guauuacuaa      120

cguuuggauc agugagagca gaugaugaag ucgauguuga uggaacagua gaggaagacc      180

ucgguaaaag uagagaaggc ucaagaacug acgacgaagu uguucaaaga gaagaagaag      240

cgauacaauu agauggauua aaugcaucac aaauaagaga acuucgugaa aaaucagaaa      300

aauuugcguu ucaagcagaa guaaacagaa ugaugaaacu aauaauaaau ucauuauaca      360

aaaauaaaga aauauuuuua agagaacuua uuucaaacgc aagcgaugca uuggauaaaa      420

uaagauugau aagucuaaca gaugaaaacg ccuuaucagg aaaugaagaa uuaacaguaa      480

aaauaaaaug cgauaaagag aaaaauuuac uacauguaac ugacacggga guaggaauga      540

caagagaaga auuagucaaa aauuugggaa caauagccaa aucaggaacc ucagaauuuc      600

uaaacaaaau gacugaagca caagaagacg ggcaaucaac aagugaauua auaggacaau      660

uugggguagg auucuacagu gcguuuuuag uagcggacaa gguaauagua accaguaaac      720

auaauaacga cacacaacau auaugggagu cagacaguaa cgaguucagu guaaucgcag      780

acccgagagg uaacacauug ggacgaggaa caacuauaac guuaguacuc aaagaagagg      840

cuucagauua ccuagaacug gauacaauaa agaaucucgu gaagaaauau ucccaauuca      900

ucaacuuccc aauauacgua uggaguucaa aaacagaaac aguggaggaa ccaauggaag      960

aagaagaagc agcuaaagaa gagaaagaag aaucagauga ugaagcugca gucgaagaag     1020

aagaagaaga aaagaaaccg aaaacuaaga aaguagagaa aacaguuugg gauugggaac     1080

uaaugaacga cauaaaacca auuuggcaac gaccgucaaa agaaguggaa gaggaugaau     1140

auaaagcauu uuacaaauca uucucuaaag aaucagauga uccaauggca uauauacauu     1200

uuacagcaga aggggaagua acauuuaagu caauccuauu uguaccaacc ucagcaccga     1260

ggggauuauu cgacgaauau ggaagcaaga aaucggauua uauaaaacua uauguaagaa     1320

ggguauuuau aaccgaugau uuccacgaua ugaugcccaa auaucuaaau uuuguaaaag     1380

gaguaguaga cagcgacgau cuaccauuaa auguaucucg agaaacacuc caacagcaua     1440

aacuccuaaa aguuauaagg aagaaauuag ucaggaaaac acucgauaug auaaagaaaa     1500

uagcagauga uaaauauaac gacacauuuu ggaaagaauu ugguacaaau auuaaauuag     1560

gaguaaucga agaucacagu aacagaacga gauuagcaaa acuauugaga uuucaaaguu     1620

cacaccaccc aacagauaua acuagcuuag accaauaugu ggaaaggaug aaagaaaaac     1680

aagauaaaau uuauuuuaug gcagggagua guaggaaaga agcugaaagu agccccuucg     1740

uggaaagauu auuaaagaaa ggauaugaag uaauauaucu aacagaacca guagacgaau     1800

auuguauaca agcacuacca gaguucgacg gaaaaagauu ucaaaaugua gccaaagaag     1860

gaguaaaauu ugacgaguca gagaaaacaa aagaaagcag agaagcagua gaaaaagaau     1920

uugaaccucu acuuaacugg augaaagaua aggcuuuaaa agauaaaaua gaaaaagcag     1980

uaguaagcca aagacuuaca gaaucaccau gugcauuggu agcaagucaa uauggaugga     2040

guggaaacau ggaaaggaua augaaagcac aagcguacca aacaggaaaa gauauaucaa     2100

cgaauuacua ugccagccag aaaaagacau ucgaaauaaa uccaagacac ccauuaauaa     2160

gagacauguu aagaagaauu aaagaagaug aagaugauaa aacuguauua gaccuugcag     2220

uaguuuuguu cgaaacggca acauuacgaa guggcuaucu gcuaccggau acaaaagcau     2280

auggagacag aauagaacga auguuaagac uaucauuaaa uauagauccu gaugccaaag     2340

uagaagaaga accagaagaa gaaccagaag aaacggcaga agauacaaca gaagacaccg     2400

aacaagacga ggaugaggaa auggacguag gaacugauga agaagaagaa acagcaaaag     2460

aaagcacugc agaaaaagau gaacuauaag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  4889
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt12)

<400>  4889
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaagagaac uaagagcauu acuauuaugg ggccgccgac      120

uaagaccucu cuuaagagcu ccagcacuag cagccguacc aggcggaaag cccauacuau      180

guccaaggag aacaacugca caacuaggac caagaagaaa uccugcuugg agucugcaag      240

cagguaggcu uuucuccaca caaacagcug aagacaaaga agaacccuua cauucaauaa      300

uaucuaguac agaaucuguu caaggaagua ccucaaaaca ugaauuucaa gcagaaacaa      360

aaaaacuacu agacauagua gcacgaucac uauauaguga aaaagaaguu uuuauaagag      420

aauuaauaag uaacgccuca gaugcacuag aaaaauuacg acacaaauua guaagcgaug      480

gucaagcuuu accagaaaug gaaauacauu uacaaacuaa cgcugaaaaa ggaaccauua      540

caauacaaga uacagguaua ggaaugacac aagaagaacu uguuaguaau cuaggaacaa      600

uagcucgauc aggaucaaaa gcauucuuag acgcauuaca aaaccaagca gaagcuagcu      660

cgaaaauaau uggucaauuu ggaguaggau uuuauucagc auucaugguu gcagacaggg      720

uagaaguaua uucacguagc gcugcaccag gaucauuagg uuaccaaugg cuaucagacg      780

guucaggcgu uuucgaaauc gcagaagcau caggaguaag aacaggaaca aaaauaauaa      840

uacaccuaaa aagugauugu aaagaguucu cuagugaagc aagaguuaga gauguaguaa      900

caaaauauuc uaauuuugua ucguuuccac uauacuuaaa uggacgaaga augaauacac      960

uacaagcaau auggaugaug gauccaaaag auguacgaga auggcaacau gaagaauucu     1020

acagauacgu ugcacaagca caugacaaac caagauauac cuuacauuau aaaaccgacg     1080

caccuuuaaa uauaagauca aucuuuuaug uuccagacau gaaacccucu auguucgacg     1140

uaucaagaga acuaggaagu aguguggccc uuuauucaag aaaaguccua auucaaacaa     1200

aagcaacaga uauauuaccu aaaugguuga gauuuaucag aggaguagua gauucagaag     1260

acaucccauu aaaucuaagu agggagcuau uacaagaauc agcauuaaua aggaaacuaa     1320

gagacguuuu acaacaaaga cuuauaaaau uuuuuauaga ucaaagcaaa aaagaugcag     1380

aaaaauacgc uaaauuuuuc gaagacuaug ggcuauuuau gagagaggga auaguaacag     1440

caacugaaca agaaguaaaa gaagacauug caaaacuacu cagauaugaa aguagugcuc     1500

ugccuagcgg ucaauuaaca agucugucug aauaugcuuc acgaaugagg gccggaacaa     1560

gaaauauaua cuacuuaugc gcaccaaacc gacacuuagc agaacauuca cccuauuaug     1620

aggcaaugaa aaagaaagac acagaaguuc uauuuugcuu ugaacaauuc gacgaacuca     1680

cuuuacuaca ccuaagagaa uuugacaaaa aaaaauuaau uagcgucgaa acagauauag     1740

ugguugacca uuauaaagaa gaaaaauuug aggauagauc uccagcggcc gaaugccuuu     1800

cagaaaaaga aacagaagaa cuuauggccu ggaugagaaa cguucuaggg ucuagaguaa     1860

caaaugugaa aguaacauua agauuagaca cacauccggc aaugguaaca guucuagaaa     1920

ugggagcggc aagacacuuu uuaagaaugc aacaauuggc aaaaacacag gaagaaagag     1980

cacaauuauu acagccaaca cucgaaauca acccuagaca cgcauuaaua aaaaaacuaa     2040

aucaacuaag agcaucagaa ccaggacuug cacaauugcu agucgaucaa auauacgaaa     2100

augcaaugau agcagcagga uuaguagaug auccacgagc gaugguagga cgacuaaaug     2160

aguuauuagu aaaagcauua gaaagacacu aaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  4890
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt12)

<400>  4890
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaauau caucacuacc aacacaacua uucaaaugcu      120

gcuucugcga cuuccuaaaa guaaaaaugc acacaauguc aucaucacac cuauucuacc      180

uagcacuaug cuuauuaaca uucacaucau cagcaacagc aggaccagaa acacuaugcg      240

gagcagaacu aguagacgca cuacaauucg uaugcggaga cagaggauuc uacuucaaca      300

aaccaacagg auacggauca ucaucaagaa gagcaccaca aacaggaaua guagacgaau      360

gcugcuucag aucaugcgac cuaagaagau uagaaaugua cugcgcacca cuaaaaccag      420

caaaaucagc aagaucagua agagcacaaa gacacacaga caugccaaaa acacaaaaag      480

aaguacaccu aaaaaacgca ucacgaggau cagcaggaaa caaaaacuac agaauguaag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  4891
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt12)

<400>  4891
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaauaccaa ugggaaaauc aaugcuagua cuacuaacau      120

uucuagcauu cgcaucaugc uguauagcag cauacagacc aucagaaaca cuaugcggag      180

gagaauuagu agauaccuua caauuuguau guggagacag aggauucuau uucucaagac      240

cagcaucaag aguaucaaga agaucaagag gaauaguaga agaaugcugu uucagaucau      300

gugacuuagc auuacuagaa acauauugcg caacaccagc aaaaucagaa cgagauguau      360

caacaccacc aacaguacua ccagauaacu uuccaagaua cccaguagga aaauuuuucc      420

aauacgauac auggaaacaa ucaacacaaa gacuaagaag aggacuacca gcacuacuaa      480

gagcaagaag aggacacgua cuagcaaaag aacuagaagc auuuagagaa gcaaaaagac      540

auagaccacu aauugcauua ccaacacaag auccagcaca cggaggagca ccaccagaaa      600

uggcaucaaa cagaaaauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  4892
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt12)

<400>  4892
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacucauucu caacaucagc auucggacca guagcauucu      120

cacuaggacu acuacuagua cuaccagccg cauucccagc accaguacca ccaggagaag      180

acucaaaaga cguugcagca ccacacagac aaccccuaac auccucagaa agaauagaca      240

aacaaauaag auacauacua gacggaauau cagcacuaag aaaagaaaca ugcaacaaau      300

caaacaugug cgaaucauca aaagaagcac uagccgaaaa caaccuaaac cuaccaaaaa      360

uggcagaaaa agacggaugc uuccaaucag guuucaacga agaaacaugc cuaguaaaaa      420

uaauaacagg acuccuagaa uucgaaguau accuagaaua ccuacaaaac agauucgaau      480

caucagaaga acaagcaaga gcaguacaaa ugucaacuaa aguacuaaua caauuccuac      540

aaaaaaaagc aaaaaaccua gacgcaauaa caacaccaga cccaacaacc aacgcaucac      600

uacucacaaa acuacaagca caaaaccaau ggcuacaaga caugacaaca caccuuauac      660

uacgaucauu caaagaauuc cuccaaucau cccuccgagc ccucagacaa auguaaggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  4893
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt12)

<400>  4893
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccauuacuau gguuaagagg auuuuuauua gcuaguugcu      120

ggauaauagu cagaucaagc ccaacgccag gaagcgaagg acacucagca gcuccagacu      180

guccaaguug ugcauuagca gcauuaccua aagauguucc uaauucacaa ccagaaaugg      240

uagaagcagu aaaaaaacau auauuaaaua uguuacacuu aaaaaaaagg ccagacguaa      300

cacaaccagu uccaaaagca gcauuauuga acgcaauaag aaaauuacac guaggaaagg      360

uaggggaaaa cggauaugua gaaauagaag acgauauagg aagaagagca gaaaugaaug      420

aacuaaugga acaaacaagu gaaauaauaa cuuucgcaga aagcggaaca gcaagaaaaa      480

cacuacacuu ugaaauaagu aaagaaggga gcgauuuauc aguaguagaa agagcagaag      540

uaugguuauu ucuaaaagua ccaaaagcaa auagaacuag aacaaaagua acaauaagac      600

uauuccaaca acaaaaacau ccacaaggau cuuuagauac uggagaagaa gcggaagaag      660

uaggacuuaa aggagaaaga ucagaacuac uauuaaguga aaaaguagua gaugcacgaa      720

aaaguacaug gcauguauuu ccaguaucca guucaauaca aagacuauua gaucaaggaa      780

aaagcagcuu agacguuaga auagcuugug aacaguguca agaaucagga gcaaguuuag      840

uuuuacuagg aaaaaaaaaa aaaaaagaag aagagggaga agguaaaaaa aaaggugggg      900

gagaaggagg agcaggagcu gaugaagaaa aagaacaauc acauagaccc uucuuaaugc      960

uacaagcaag acaaucagaa gaucauccac auagaagaag acgaagaggc uuagaaugug     1020

auggaaaagu aaauauaugu ugcaaaaaac aauucuuugu aucauuuaaa gauauaggau     1080

ggaaugauug gauaauugca cccagcgguu aucaugcaaa cuauugugaa ggagaaugcc     1140

caucacacau agcgggaacu aguggaaguu cauuaagcuu ucacucaacu gugauaaauc     1200

auuaucguau gagaggccau ucgccguuug caaauuuaaa aucauguugu guaccaacaa     1260

aacuaagacc aaugaguaug uuauauuaug acgauggaca aaauauaaua aagaaagaca     1320

uacaaaauau gauaguagaa gaauguggau guaguuaagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  4894
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt12)

<400>  4894
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggauuac cuggcagagc uuugggagca gcaugucuau      120

uacuauuagc ugcaggaugg uuaggaccag aagcaugggg aucgccaaca ccaccaccaa      180

caccagcugc accaccacca ccaccaccuc cugguucacc aggcgggucu caagacaccu      240

guacaagcug uggaggcuuu aggaggccag aagaacuagg aagaguagau ggagacuuuu      300

uagaagcugu aaaaagacau auacuuagua gacuccaaau gagaggaaga ccaaauauaa      360

cacaugccgu accaaaagcu gcaaugguaa cugcacuucg aaaacuacau gcaggaaaag      420

uaagagaaga uggaagggua gaaauaccuc aucuagaugg acaugcauca ccaggagcag      480

auggacaaga aagaguauca gaaauaauau cuuuugcaga aacagaugga uuagcgucau      540

caagaguaag auuauacuuu uucauaucaa acgaaggaaa ucaaaauuua uuuguaguac      600

aagcgagcuu augguuauau cuaaaauuau uacccuaugu uuuagaaaaa ggaucaagac      660

gaaaaguaag aguaaaaguu uauuuucagg aacaaggaca cggagacaga uggaauaugg      720

uagaaaagag aguagacuua aaaagaagug gauggcauac auucccacua acugaagcaa      780

uucaagcacu auuugaaaga ggagaaagaa gauuaaaccu agaugugcaa ugugauucuu      840

gucaagaauu agcagucgua ccaguauuug uugauccagg agaagaaagu cauagaccau      900

uugugguagu ucaagcaaga uuaggagaua guagacauag gauaagaaaa agaggauuag      960

aaugugaugg aaggacaaau uuauguugua gacaacaauu cuuuauugac uuuagauuaa     1020

uaggauggaa ugauuggaua auagcaccca caggauauua ugggaauuau ugugaaggaa     1080

guuguccagc auacuuagca ggaguacccg gaucagcaag uuccuuucau acagcaguug     1140

ucaaccaaua ucgaaugaga ggguuaaauc cagguacagu aaacucaugu uguauaccaa     1200

ccaaacuaag uacuaugagc auguuauauu uugaugauga auauaacauu guaaaacgag     1260

auguaccaaa caugauagua gaagaaugug gaugugcaua aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  4895
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt12)

<400>  4895
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcauuaagag uauuacugcu gacagcuuug acucuauguc      120

acggcuucaa ccuagacaca gaaaaugcua ugaccuuuca agaaaaugca cgagguuucg      180

gacagucugu cguccaacua caaggaucaa ggguuguagu cggcgcaccc caagaaauug      240

uagcagcaaa ucaaagaggc uccuuauauc aaugcgacua cucaacaggu agcugcgaac      300

caauacgucu ucaaguuccc guugaagcag ugaacauguc acuugguuua aguuuagcag      360

cuacaacaag cccaccucaa cuauuagcuu gcggccccac aguacaccaa accuguagcg      420

aaaauacuua uguuaaagga uuguguuucc uauucgguuc caauuuacga cagcaaccuc      480

aaaaauuccc ugaagcacuu cguggaugcc cccaagaaga uagcgauaua gcauuuuuaa      540

ucgacgguuc cggauccaua auaccccaug acuuccggag aaugaaagaa uuuguaagua      600

cagugaugga acaauugaag aaaucuaaaa cucuauuuuc ucugaugcaa uauagugaag      660

aauuuaggau acacuuuacu uuuaaagaau uucaaaacaa cccaaauccg agaucguuag      720

uaaaaccgau uacucagcuu uuaggacgaa cucauacagc uacuggaaua cguaaaguag      780

uaagagaacu cuucaacaua acaaauggcg cacguaaaaa ugcuuuuaag auauuaguag      840

uaauuacaga cggagaaaaa uucggagauc cucuaggaua cgaagacgua auaccagaag      900

cugauagaga gggcguaaua agauauguaa uaggcguugg agaugcauuc agaagcgaga      960

aaagcagaca agaauugaac acaaucgcau cuaaaccccc acgagaucau guauuccagg     1020

ucaauaauuu cgaagcucua aaaacaauac aaaaccaacu gagagagaaa auauuugcaa     1080

uagaagggac acaaacaggc ucaucgagcu cauuugaaca ugaaaugagc caagaaggau     1140

uuucagcagc aauaaccuca aacggaccac uauuauccac uguuggaagu uaugauuggg     1200

cagggggagu cuucuuauac acguccaaag aaaaaucuac auuuauaaac augaccagag     1260

uugacaguga caugaaugac gcuuaccucg gcuaugcagc agcuauuaua cuacgaaaua     1320

gaguacaauc acuuguuuua ggggcaccac gguaccaaca uauuggucua guugccaugu     1380

uccgacaaaa uacaggaaug ugggaaucaa augccaaugu aaaaggaaca caaauaggag     1440

cuuauuucgg cgcaucauua uguuccguag auguagacuc aaacggauca acagauuuag     1500

uccugauugg ugccccacau uauuaugaac aaacaagagg uggucaggua aguguuuguc     1560

cgcucccacg agguagagcc cgauggcaau gcgaugcugu acuuuaugga gaacaaggac     1620

agccaugggg aagauucggg gcagcacuaa caguacuagg ugacgugaau ggggauaaac     1680

uaaccgaugu agcaauaggu gcaccaggcg aagaagacaa uagaggagca guauacuuau     1740

uucacggaac aucaggcuca ggaauaagcc cuucgcacuc acaaagaauc gcuggcagua     1800

aauuaagccc ucgccuucaa uacuuuggac agucgcuuag uggaggccaa gaucuaacaa     1860

uggacggauu aguugaccua acgguaggag cacaggguca uguccuacua uuacgauccc     1920

aaccuguuuu gcgugucaaa gcaauuaugg aguucaaucc aagagaagua gcacgaaaug     1980

uuuuugaaug caaugaucaa guaguuaaag gcaaagaagc uggagaagua cggguuuguc     2040

uacauguaca aaaauccaca cgagaccguc uacgcgaagg ucaaauacaa ucaguaguua     2100

ccuaugaucu ugcacuugac ucuggaagac cucacucuag ggcuguauuu aaugaaacua     2160

aaaauuccac gagacgacaa acacaaguac uaggucuuac ccaaacuugu gaaaccuuaa     2220

agcuacaacu cccaaauugc auagaagauc caguaagucc aauaguacug agacucaauu     2280

ucucccuugu cggaaccccu cuaagcgcgu ucggaaacuu acgaccagua cuagcagaag     2340

acgcacagag acuuuuuacu gcacuuuuuc cauucgagaa aaauugcgga aacgacaaua     2400

uaugucaaga cgacuuaucu auaacauuuu cauucauguc auuagauugu uugguaguug     2460

gagguccccg ggaguucaau gucacaguaa cagucagaaa ugauggagaa gauucuuacc     2520

gaacacaagu uaccuuuuuc uuuccacuug auuuaagcua ccgaaaaguc ucuacacuac     2580

agaaccaacg aagucaacgc ucguggagac uugcauguga aagcgcuucu ucaacugaag     2640

uuucaggugc uuugaaauca acaucaugua guauaaacca ucccauuuuu ccggaaaauu     2700

cugaaguuac auuuaacauu acguucgaug ucgauucaaa ggcuucucuu gguaauaaau     2760

uacuauugaa agcaaauguc acauccgaaa auaauaugcc aaggaccaac aaaacagagu     2820

uccaacuuga auuaccugua aaauaugcug ucuacauggu uguaacauca cauggaguau     2880

cuaccaaaua ucucaauuuu acagcaucug aaaauacuuc acgaguaaug caacaccaau     2940

accaaguauc aaauuuagga caacgaucac ucccaauuag ucuuguuuuu cuagucccag     3000

ucagauugaa ucaaacagua aucugggaua gaccacaagu aacauuuucu gaaaacuuaa     3060

gcaguacaug ucauacaaaa gaacgcuuac caucccauuc cgacuuucuu gcugaauuaa     3120

gaaaagcacc ugucgucaau ugcucaaucg cagugugcca acgaauacaa ugugacauuc     3180

ccuucuuugg cauacaagaa gaguuuaacg cuacacuaaa gggcaauuua uccuuugacu     3240

gguacauaaa aacaucacau aaucaucuau uaauuguauc aacagcagaa auauuauuua     3300

acgacagcgu auucacacuu cuccccgggc aaggagcuuu ugucagaagu caaacagaaa     3360

caaaaguaga accauucgaa guuccaaacc ccuuaccucu cauaguaggu uccucgguag     3420

guggauuacu acugcuugca uuaauuacag ccgcuuuaua uaaacuugga uucuuuaaga     3480

gacaauauaa ggauaugaug ucugaaggag gaccuccugg cgcagaacca caauaaggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  4896
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt12)

<400>  4896
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucacuua aaacucuccc auucuuacua cuacuacacg      120

uccaaauauc aaaagccuuc cccguauccu caaaagaaaa aaauacuaaa acaguucaag      180

acuaccucga aaaauucuac caacuaccuu caaaccaaua ccaaucaaca agaaaaaaug      240

guacuaaugu cauagucgaa aaauuaaaag aaaugcaaag auuuuuugga cuuaacguua      300

caggaaaacc uaacgaagaa acccuagaca ugaugaaaaa accacgaugc ggagucccag      360

acucaggagg cuucaugcua acaccaggaa auccaaaaug ggaacguaca aacuuaacau      420

accgcauacg aaacuacacc ccacaacuaa gugaagcaga aguagaacgc gccauaaaag      480

acgccuucga acuaugguca guagcaagcc cacucauauu uacuagaaua ucacaaggug      540

aagcugauau caauaucgca uuuuaccaac gagaccacgg cgauaacuca ccauucgacg      600

gcccaaaugg aauacuagcc cacgcauucc aaccaggaca aggaauagga ggugacgcac      660

acuucgacgc agaagaaacc uggacaaaca caucagcaaa cuauaacuua uuucuagucg      720

ccgcacacga auucggacac ucacuagguu uagcacacuc aucagaccca ggcgcacuaa      780

uguaucccaa cuaugcauuc agagaaaccu caaauuauuc auuaccucaa gacgauauag      840

acggaauuca agcaauauau ggacuuucuu caaauccaau acaaccaaca ggcccuucaa      900

ccccaaaacc cugugauccc ucacuaacau ucgacgcaau cacaacucua cgaggagaaa      960

uuuuauucuu uaaagacaga uauuuuugga gaagacaccc acaacuacaa agaguagaaa     1020

ugaacuucau aagcuuauuc uggccaucac uaccaacagg cauucaagca gcauacgaag     1080

acuucgauag agaccuaaua uucuuauuua aaggaaacca auauugggca cuaucagguu     1140

acgacauacu acaaggauac ccaaaagaca uauccaauua uggauuccca ucaucaguac     1200

aagcaauaga cgcagcagua uucuauagau caaaaaccua cuucuucgua aaugaucaau     1260

ucuggagaua cgacaaccaa cgccaauuca uggaacccgg auaucccaaa ucaauaucag     1320

gagcauuccc aggaauagaa ucaaaaguag acgcuguauu ccaacaagaa cauuucuuuc     1380

augucuucuc cggacccagg uacuacgcau uugauuuaau agcccaaaga guaacacgag     1440

uagcaagagg aaauaaaugg uugaauugua gauacggaua aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  4897
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt12)

<400>  4897
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuuuggc aacccuuagu uuuaguuuua cuaguauuag      120

gaugcugcuu cgcagcuccu agacaaaggc aaucaacacu uguucucuuu ccaggagacu      180

uacgaacaaa ucuaacagau agacaacuag cagaagaaua cuuauauaga uauggauaua      240

ccagaguugc agaaaugaga ggagaaagua aaucguuagg accugcccua cuacuucuuc      300

aaaaacaauu aucauuacca gaaacaggag aacuagauuc ugcuacacua aaagcaauga      360

gaaccccuag augcggaguu ccagauuuag gccgauuuca aacauuugaa ggagaccuaa      420

aauggcacca ucauaauaua acuuauugga uacaaaauua cucugaagac uuaccgagag      480

ccguaauaga cgaugcauuc gcuagagcau uugcuuuaug gucagcaguu acaccccuaa      540

cauuuacuag aguauauuca agagaugcug auauaguaau ucaauuugga gucgcagaac      600

auggugaugg auauccauuu gauggaaaag acggauuauu agcccacgca uucccaccug      660

guccaggcau ucaaggagau gcacauuucg acgaugacga auuauggagc uuaggaaaag      720

gaguaguagu accuacacgc uuugggaaug cugauggagc agcaugccau uucccauuua      780

uuuucgaagg uagaucauac ucugcaugca cuacagaugg aagauccgau ggauuaccuu      840

ggugcagcac aacagcuaau uaugacacug augacagauu ugguuuuugu ccauccgaaa      900

gacuuuacac acaagacgga aaugcagaug guaaaccaug ccaauuuccu uuuauauuuc      960

agggacaauc auauucagcu uguacaacag augggagaag ugauggauac cgcuggugug     1020

caaccacugc caauuaugau agagacaagc uauuuggauu cuguccuaca agagcagacu     1080

cgacuguaau ggguggaaau ucagccggag aacuaugugu cuucccauuu acauuuuuag     1140

guaaagaaua cucuacaugu acuucagaag gccgugguga uggaagacuu uggugugcaa     1200

caacaucaaa uuucgacucu gacaaaaaau ggggauuuug uccagaucaa ggauacagcu     1260

uauuucuagu ugcagcacac gaauuuggac augcacuagg uuuagaucac aguucaguac     1320

cagaagcauu aauguaucca auguauagau uuaccgaagg gccuccccuu cacaaagaug     1380

acguuaaugg aauaagacac uuauacggac ccagaccuga accugaacca agaccuccua     1440

cuacaacuac uccacaacca acagccccac caacaguaug cccaacggga ccgccaacag     1500

uacacccaag cgaaagacca acugcuggac caacaggacc acccagugca gguccaacug     1560

guccaccuac agcaggccca ucuacugcaa caacaguccc auuaagucca guggacgaug     1620

caugcaacgu uaacauauuc gacgcaauug cagaaauugg aaaucaauua uaucuuuuua     1680

aagauggaaa auacuggagg uucucagaag gaagagguuc aagaccacaa gguccauuuc     1740

uuauagcuga uaaauggcca gcucucccca gaaaauuaga cucaguauuc gaagaacgau     1800

uaaguaaaaa auuauucuuc uuuucaggca gacaaguuug gguauauacu ggugcaagug     1860

uacucggacc aagaagacuu gauaaauuag gcuuaggggc agacguugca caaguaacug     1920

gagcccuaag auccggucga ggaaaaaugu uauuauucuc aggaagaaga uuauggagau     1980

uugauguuaa agcacaaaug guugauccaa gaucagcauc agaaguagac agaauguuuc     2040

caggcguacc acuagauacu caugacguau uucaauaucg ggaaaaagcg uacuuuuguc     2100

aagauagauu uuauuggaga guuucuucaa gaucagaauu aaaccaagua gaucaaguug     2160

gauauguaac auaugauauc cuacaaugcc cagaagacua aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  4898
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt12)

<400>  4898
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacccaggag uacuagcagc auucuuauuc uuaucuugga      120

cccacuguag agcacuaccu cuaccuagcg gaggagauga agaugaccuc ucagaagaag      180

accuacaauu cgcagaaaga uaucuacgau cuuauuacca cccaacaaac uuagcaggaa      240

uacuaaaaga aaacgcugca ucaucaauga cagaaagacu aagagaaaug caaucauuuu      300

ucggacuaga aguaacagga aaauuagacg acaacacauu agacguaaug aaaaaaccaa      360

gaugcggagu accagauguc ggagaauaca acgucuuccc aagaacauua aaauggagca      420

aaaugaaccu aacauauaga auaguaaauu acacacccga caugacacac ucagaaguag      480

aaaaagcauu uaaaaaagca uucaaaguau gguccgaugu cacaccccua aacuucacaa      540

gauuacauga cggaauagca gacauaauga uaucuuucgg aauaaaagaa cacggugacu      600

ucuacccuuu cgacggacca ucaggacuau uagcacacgc auucccaccc ggaccaaauu      660

acggaggaga ugcacacuuu gacgaugaug aaacuuggac aucaucauca aaagguuaua      720

acuuauuucu cguagcugcc cacgaauucg gacacucacu agggcuagac cacagcaaag      780

accccggagc auuaauguuu ccaauuuaua cauauacagg aaaaagucac uuuaugcuac      840

cggacgacga cguacaaggc auacaaucac ucuacggucc aggagacgaa gacccaaacc      900

caaaacaccc caaaacacca gauaaaugcg acccaucacu aucauuagau gcaauaacau      960

cauuaagagg agaaacuaug auuuucaaag acagauucuu cuggagguua cacccccaac     1020

aaguagaugc agaacucuuu cuaacaaaau cauuuuggcc agaauuacca aauagaauug     1080

acgcugcaua cgaacaccca ucacacgacc uaauauuuau auucagagga agaaaauucu     1140

gggccuuaaa cggauaugac auacuagaag gauacccaaa aaaaauauca gaauuagguc     1200

uacccaaaga aguaaaaaaa auaucagcag ccguccacuu cgaagacacu ggaaaaacau     1260

uacucuuuag uggcaaccaa guauggagau augacgauac aaaccacaua auggauaaag     1320

acuacccaag auuaauagaa gaagacuuuc caggaauugg agacaaagua gacgccguau     1380

acgaaaaaaa uggauacaua uacuuuuuca acggaccaau ucaauucgaa uauuccauau     1440

ggucaaaccg aauaguuagg guaaugccag caaacuccau auuauggugu uaaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4899
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt12)

<400>  4899
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacaccaa auacaacaga agacuaugac acaacuacag      120

aauucgacua uggcgacgcc acaccaugcc aaaaaguaaa cgaaagagca uucggcgcac      180

aauuauuacc accuuuauac ucauuaguau ucguaauagg auuaguagga aacauacuag      240

uaguauuagu acuaguacaa uacaaaagac uaaaaaacau gacauccaua uaccuacuaa      300

acuuagcaau aucugaccua cuauuccuau ucacucuacc auucuggauc gacuauaaac      360

uaaaagauga cuggguuuuc ggugacgcaa ugugcaaaau ccucucagga uuuuacuaca      420

caggauuaua cagcgaaauc uuuuucauca uacuauuaac caucgaccga uaccuagcca      480

uaguacacgc aguauucgca cucagagcca gaacaguaac uuucggcgua auaacaucaa      540

uaauaaucug ggcauuagcc auacucgcau caaugccagg acuauacuuc ucaaaaacac      600

aaugggaauu cacccaucac acaugcucau uacacuuccc ucacgaaucc uuaagagaau      660

ggaaacuauu ucaagcccua aaauuaaacu uauucggacu aguacuaccu uuacuaguaa      720

ugauaaucug uuacacagga auuauaaaaa uacuacucag aagacccaac gaaaaaaaau      780

caaaagccgu aagauuaaua uucguaauaa ugauaauuuu cuucuuauuc uggacaccau      840

acaacuuaac aauacucauu uccgucuucc aagacuucuu auucacucac gaaugcgaac      900

aaucaagaca ucuagaccua gcaguccaag ucaccgaagu aauagcauac acacacugcu      960

gcguaaaccc aguaauuuac gcauucguag gagaacgauu cagaaaauac cuuagacaac     1020

uuuuucacag aagaguagca guccaccuug ucaaauggcu accauuuuua ucuguagaca     1080

gacuagaaag aguaucuuca acaucaccau cuacaggaga acacgaacuc ucugccggcu     1140

uuuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  4900
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt12)

<400>  4900
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgaacacuag ccugccuauu acuacuagga ugcggauacc      120

uagcacacgu acuagcagaa gaagcagaaa uaccaagaga aguaauagaa agacuagcaa      180

gaucacaaau acacaguaua agagaccuac aaagacuacu agaaauagac ucaguaggau      240

cagaagacuc acuagacaca ucacuaagag cacacggcgu acaugcaaca aaacacguac      300

ccgaaaaaag accauuacca auaagaagaa aaagaagcau agaagaagcc guaccagcag      360

uauguaaaac aagaacagua auauacgaaa uaccaagaag ccaaguagac ccaacaucag      420

ccaacuucuu aauauggcca ccaugcguag aaguaaaaag augcacagga ugcugcaaca      480

caagcagcgu caaaugccaa ccaaguagag uacaccaucg aucaguaaaa guagcaaaag      540

uagaauacgu cagaaaaaaa ccaaaacuaa aagaaguaca aguaagacuc gaagaacacc      600

uagaaugcgc augcgccaca acaagccuaa acccagacua cagagaagaa gacacaggaa      660

gaccaagaga aucaggaaaa aaacgaaaaa gaaaaagacu aaaaccaacu uaaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  4901
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt12)

<400>  4901
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagaugcu gggcacuauu ccuaucauua ugcuguuacu      120

uaagacuagu aucagcagaa ggagauccaa uaccagaaga auuauacgaa auguuaagug      180

aucacucaau aagaagcuuu gacgauuuac aaagacuacu acauggagau ccaggagaag      240

aagacggagc agaacuugau cuaaauauga caagaucaca caguggagga gaauuagaau      300

cacuagccag aggaagaaga agucuaggau cacucacaau cgcagaacca gcaaugauag      360

cagaauguaa aacaagaaca gaagucuucg aaaucucaag acgacuaaua gacagaacaa      420

augcaaacuu cuuaguaugg ccaccaugcg uagaaguaca aagaugcuca ggaugcugca      480

auaacaggaa cguacaaugu agaccaacac aaguacaacu aagacccgug caaguaagaa      540

aaauagaaau aguaagaaaa aaaccaaucu uuaaaaaagc aacaguaaca cuagaagauc      600

aucuagcaug caaaugcgaa acaguagcag cugcaagacc aguaacaaga ucaccaggag      660

gaagccaaga acaaagagca aaaacgccac aaacaagagu aacaauaaga acaguuagag      720

uaagaagacc accaaaagga aaacauagaa aauucaaaca cacacacgau aaaacagcau      780

uaaaagaaac auuaggagca uaaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  4902
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt12)

<400>  4902
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucauuauucg gauuauuacu uuuaacaucu gcauuagcag      120

gacaaagaca aggaacacaa gcagaaucaa accuaucaag caaauuucaa uuuucaucaa      180

auaaagaaca aaauggcgua caagauccac aacacgaaag aauaauaaca guaagcacua      240

acggaucaau acacagcccc cgauucccac auacauaccc aagaaacaca guauuaguau      300

ggagauuagu cgccguagaa gaaaauguau ggauacaacu uacauucgau gaaagauucg      360

gauuagaaga ccccgaagac gacauaugca aauacgacuu cguagaagua gaagaacccu      420

cagacggaac aauauuaggu cguuggugcg gaucaggaac aguaccagga aaacaaauaa      480

guaaaggaaa ccaaauaaga auucgauucg uaucagauga auacuuucca ucagaaccag      540

gauucugcau ccauuacaau auaguaaugc cacaauuuac agaagcagua ucaccaagcg      600

uauuaccacc aucagcccua ccucuagacu uauuaaauaa cgcaauaaca gcauuuagca      660

ccuuagaaga cuuaauacga uacuuagaac cagaacgaug gcaacuagac cuugaagacc      720

uauacagacc aacauggcaa uuacuaggaa aagcauucgu cuuuggcaga aaaucaagag      780

uaguagaucu aaaccuacua acagaagaag uaagauuaua caguugcaca ccuagaaacu      840

ucucaguaag cauaagagaa gaacuaaaaa gaacagacac cauauucugg ccaggaugcc      900

uacuaguuaa aagaugcgga ggaaauugcg cauguugcuu acacaacugu aacgaaugcc      960

aaugcguacc cucaaaagua acaaaaaaau accacgaagu acuacaauua agaccaaaaa     1020

caggaguaag aggacuccac aaaucacuua cagacguagc acuagaacac cacgaagaau     1080

gugacugcgu augcagaggc ucaaccggag gauaaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  4903
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt12)

<400>  4903
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauagauuaa uauucguaua cacacuaaua ugugcaaacu      120

ucugcucaug cagagacacc agugcaacac cccaaagcgc aucaauaaaa gcacuacgaa      180

acgcaaacuu aagaagagac gaucuauaua gaagagauga aacaauacaa guaaaaggaa      240

acggauacgu acaaucacca cgauuuccaa auucauaccc acgaaaccua uuauuaacau      300

ggcgacuaca cucacaagaa aauacaagaa uacaacuugu cuucgacaac caauucggac      360

uagaagaagc agaaaaugac auaugcagau augacuucgu agaaguagaa gacauaucag      420

aaacuucaac aauaauaaga ggaagauggu guggacacaa agaaguccca ccaagaauaa      480

aaucaagaac aaaccaaaua aaaauaaccu ucaaaucaga ugacuacuuc guagcaaaac      540

cgggcuuuaa aauauacuau agccuauuag aagacuucca accagcagca gcaucagaaa      600

ccaacuggga aucaguaaca agcucaauau cuggaguauc auacaacuca ccaucaguaa      660

cagauccaac acuaauagca gacgcauuag acaaaaaaau agccgaauuc gacacaguag      720

aagaucuacu aaaauacuuc aacccagaau cauggcaaga agaccuagaa aacauguacc      780

uagacacacc aagauacaga ggaagaucau accaugacag aaaaaguaaa guagaccuag      840

acagacuaaa cgacgaugca aaaagauaca gcugcacacc aagaaauuac ucaguaaaca      900

uaagagaaga acuaaaacua gcaaacguag uauucuuccc aagaugcuua uuaguacaaa      960

ggugcggagg aaauugugga ugcggaacag uaaacuggag auccuguaca ugcaacucag     1020

gcaaaacagu caaaaaauac cacgaaguac uacaauucga accaggacac auaaaaagaa     1080

gaggcagagc aaaaacaaug gcacuaguag acauacaacu cgaucaccac gaaagaugcg     1140

acuguauaug cucaagcaga ccaccacgau aaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  4904
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt12)

<400>  4904
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaacacacu caaaauuccc agcagcagga augucacgac      120

cucuagacac aucauuacga cuaaaaacau ucucaucaaa aucugaauac caacuaguag      180

uaaacgcagu aagaaaauua caagaaucag gauucuacug gucagcagua acaggaggag      240

aagcaaaccu acuauuauca gcagaaccag caggaacauu ccuaauaaga gacucaucag      300

accaaagaca cuucuuuaca cuaucaguaa aaacccaauc uggaacaaaa aaccuacgaa      360

uacaauguga aggaggaucc uucucucuac aaucagaccc aagaucaaca caaccaguac      420

ccagauuuga cugcguacua aaauuaguac accacuacau gcccccaccc ggagcaccau      480

cauucccauc acccccaaca gaacccucau cagaaguacc agaacaacca ucagcacaac      540

cacuaccagg cucaccacca agaagagcuu auuacauaua cuccggagga gaaaaaauac      600

cacuaguucu aucaagaccc uuaucaucaa acguagccac acuacaacac cuaugcagaa      660

aaacaguaaa cggacacuua gacucauacg aaaaaguaac acaacuucca ggaccaauaa      720

gagaauucuu agaucaauac gacgcaccau uauaaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  4905
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt12)

<400>  4905
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaccaucag caggacaauu agcauuauuc gcauuaggaa      120

uaguauuagc agcaugucaa gcauuagaaa auucaacauc accauuauca gcagacccac      180

caguagcagc agcaguagua ucacauuuua augauugccc agauucacau acacaauucu      240

gcuuucaugg aacauguaga uuuuuaguac aagaagauaa accagcaugu guaugucauu      300

caggauaugu aggagcaaga ugugaacaug cagauuuauu agccguagua gcagcaucac      360

aaaaaaaaca agcaauaaca gcauuaguag uaguaaguau aguagcauua gcagucuuaa      420

uaauaacaug uguauuaaua cauuguuguc aaguaagaaa acauugugaa uggugcagag      480

cauuaauaug uagacaugaa aaaccaucag cacuauuaaa aggaagaaca gcauguuguc      540

acucagaaac aguaguauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  4906
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt12)

<400>  4906
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaccaagug gauuaagacu acuaccauua cuauuaccac      120

uauuauggcu acuaguauua acaccuggaa gaccagcugc aggccuauca accugcaaaa      180

caauagacau ggaacuagua aaacgaaaaa gaauagaagc aauaagaggc caaauacuau      240

caaaacuaag auuagcauca ccaccuuccc aaggagaagu accaccaggc ccacuaccag      300

aagcaguacu agcacuauac aacuccacaa gagacagagu agcaggcgaa ucagccgaac      360

cagaaccaga accagaagcu gacuacuacg caaaagaagu aacuagagua uuaaugguag      420

aaacacacaa cgaaaucuau gacaaauuua aacaaucuac acauucuaua uauauguucu      480

ucaauacaag cgaauuacga gaagcaguac ccgaaccagu acuauuauca agagcugaac      540

uccgauuacu aagauuaaaa cuaaaaguag aacaacacgu agaacuauac caaaaauauu      600

cuaauaauuc auggagauau cuuagcaaua gauuacuagc accauccgac ucaccugaau      660

ggcuaucauu ugauguaaca ggaguaguac gucaauggcu aucacgaggc ggagaaauag      720

aaggauuuag auuaagcgcu cacugcagcu gugacucaag agacaacaca uuacaaguag      780

acaucaacgg auucacaaca ggaagaagag gagaucuagc cacaauacac ggaaugaaca      840

gaccauuucu acuauuaaug gcaacaccac uagaaagagc acaacaucua caaucuucaa      900

gacacagaag agcauuagac acaaacuacu gcuuuucaag cacagaaaaa aauugcugcg      960

ucagacaauu auauauagau uucagaaaag auuuaggcug gaaauggaua caugaaccaa     1020

aaggauacca cgcaaacuuc ugccuaggac caugcccaua cauuugguca uuagauaccc     1080

aauacucaaa aguucuugca uuauacaacc aacacaaccc uggagcaagu gcagcaccau     1140

guugcguacc ccaagcauua gaaccacuac caauaguaua uuacguuggc cgaaaaccca     1200

aaguagaaca acuaucaaac augauaguca gaucauguaa auguucauaa ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  4907
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt12)

<400>  4907
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uacucucagc cuuccuaaua cuacaccuag      120

uaacaguagc auuaagcuua ucaacaugcu caacacuaga cauggaucaa uucaugagaa      180

aaagaauaga agcaauaaga ggccaaauac uaucaaaacu uaaauuaaca ucaccaccag      240

aagacuaucc cgaaccagaa gaaguaccac cagaaguaau aucaauauau aacucaacaa      300

gagaccuauu acaagaaaaa gcaagccgaa gagcagcagc augcgaacga gaaaggucag      360

acgaagaaua cuacgccaaa gaaguauaca aaauagacau gccacccuuc uucccaucag      420

aaaaugccau accccccaca uuuuacagac cauacuucag aaucguaaga uucgacguau      480

cagcaaugga aaaaaacgca ucaaaucuag uuaaagcaga auucagagua uucagacuac      540

aaaacccaaa agcaagagua ccagaacaaa gaauagaacu auaccaaaua cuuaaaucca      600

aagaucuaac aucaccuaca caaagauaua uagacucaaa aguaguaaaa acuagagcag      660

aaggcgaaug gcuauccuuc gacguaacag acgccguuca cgaauggcuu caccacaaag      720

accgaaacuu aggauucaaa auaucacuuc acuguccaug uugcacauuu guccccucaa      780

auaacuacau aauccccaau aaaucagaag aacucgaagc aagauucgcc ggaauagacg      840

gaacuagcac auauaccucc ggagaccaaa aaaccauaaa aucuacaaga aaaaaaaacu      900

cuggaaaaac accacacuua cuauuaaugc uacuacccuc auaccgacuc gaaucucaac      960

aaacaaacag acgaaaaaaa agagcauuag acgccgcuua uuguuucaga aauguacaag     1020

auaacugcug ccuacgacca cuauacauag auuucaaaag agaucuaggc uggaaaugga     1080

uccaugaacc aaaaggcuau aacgcaaacu ucugcgcugg agcaugccca uaccuauggu     1140

caucagacac acaacauuca agaguauuau cacuuuacaa caccauaaau cccgaagcau     1200

cagcaagccc cuguugcgua ucacaagacc uagaaccacu aaccauccua uacuauauag     1260

gaaaaacucc aaaaauagaa caacuaucua auaugauagu aaaaucaugc aaaugcucuu     1320

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  4908
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt12)

<400>  4908
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaugcacu uacaaagagc ccuaguaguc cuagcuuuac      120

uuaacuucgc aaccguaucc cuaagccuau caacuuguac aacccuagac uuuggacaca      180

uaaaaaaaaa acgcguagaa gcaauuagag gacaaauauu aucuaaacua agauuaaccu      240

caccaccaga accaacagua augacacaug uaccauacca gguauuagca cuauacaauu      300

caacacgcga acuacuagag gaaaugcaug gagaaagaga agaaggaugc acacaagaaa      360

acacagaauc agaauacuac gcaaaagaaa uccauaaauu cgacaugaua caaggauuag      420

cagaacacaa cgaacuagca guaugcccaa aaggaauaac aucaaaagua uuuagauuca      480

auguaucuuc aguugaaaaa aauagaacua accucuuuag agccgaauuc cgcguauuaa      540

gaguccccaa cccaagcagc aaacgaaacg aacaaagaau agaacuauuc caaauacuaa      600

ggccagacga acacauagca aaacaaagau auauaggagg caaaaauuua cccacaagag      660

guacagcaga auggcuauca uucgauguaa cagauaccgu aagagaaugg cuacuaagaa      720

gagaaaguaa ucuaggccua gaaauaucaa uacauugucc augucacaca uuccaaccaa      780

acggagacau auuagaaaac auacacgaag uaauggaaau aaaauucaaa ggaguagaca      840

acgaagauga ucacggacga ggcgaucuag gcagauuaaa aaaacaaaaa gaccaccaca      900

auccacaccu aauauuaaug augauaccac cacacagacu agacaaucca ggccagggag      960

gccaaagaaa aaaaagggca cuagacacca acuacugcuu cagaaaccua gaagaaaacu     1020

gcugcguaag accacuauac auugacuuca gacaagaccu aggcuggaaa uggguccaug     1080

aaccaaaagg auacuacgcc aacuuuugcu caggaccaug cccauaccuc agaucagcag     1140

acacaaccca cucaacagua uuagguuuau acaacacauu aaacccagaa gcaagugccu     1200

ccccuuguug cguaccacaa gaccuagaac cauuaaccau auuauauuau guaggacgaa     1260

caccaaaagu agaacaacua ucaaauaugg uaguaaaauc augcaaaugu agcuaaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4909
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt12)

<400>  4909
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuccuguag ccguaugggc agcucuagcc guaggauuag      120

aauuaugggc ugcugcccau gcacuaccug cccaaguugc uuuuacacca uacgcaccag      180

aaccugguuc aacauguaga uuaagagaau auuaugauca aacugcucaa auguguuguu      240

caaaauguag cccuggucaa caugccaaag uauucuguac uaaaacuucu gauaccguau      300

gugauucaug ugaggauuca acauauacac aauuauggaa uuggguacca gaauguuuau      360

cauguggauc ucgauguuca ucagaucaag uagaaacaca agcuuguaca agagaacaaa      420

auagaauaug uacuuguaga ccagguuggu acugcgccuu aucaaaacaa gaaggaugua      480

gacuaugcgc cccacuacga aaauguagac caggauuugg uguugcacgu ccaggaacag      540

aaacaucaga cguaguaugu aaaccaugcg cucccgguac auucucaaau acaacaucau      600

ccaccgauau augucgacca caucaaauau guaauguagu agcaauacca ggaaaugcau      660

cuauggacgc aguauguaca ucaacaucac ccacaagauc aauggcacca ggugcugucc      720

aucuaccaca accuguuuca acaagaucac aacauacaca accuacaccc gaaccaucca      780

cagcaccaag uaccucauuu cuuuuaccua ugggaccauc accaccugca gaaggaucaa      840

caggagauuu ugcacuucca guaggacuaa uaguuggagu aacugcacua ggauuauuaa      900

uaauuggagu cguaaauugu guaauaauga cacaaguaaa aaaaaaacca uuaugcuuac      960

aacgagaagc caaagucccu cauuuaccag cagacaaagc uagaggaacc caaggaccag     1020

aacaacaaca ccuacucaua accgcaccuu caucaucuuc aucaucuuua gaaucaucug     1080

caucugcauu agauagaaga gcacccacaa gaaaucaacc acaagcaccu ggaguugaag     1140

cuuccggggc aggugaagcu cgagcuucaa caggaucuuc agauucaucu ccaggugguc     1200

auggaaccca aguuaaugua acuugcaucg uaaauguaug uucaucauca gaucacucau     1260

cacaauguuc aucacaagca aguucaacua ugggagauac ugacucaagc ccaucggaau     1320

caccuaaaga ugaacaagua ccauuuagua aagaagaaug ugcauuuaga ucucaacuug     1380

aaacaccaga aacuuuauua ggaaguacag aagaaaaacc acuaccauua ggaguacccg     1440

augcagggau gaaaccuucc uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  4910
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt12)

<400>  4910
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaguaauga ggcuauuucc auguuuuuua caauuacuag      120

caggauuagc auuaccagca guaccaccac aacaaugggc auuaagugca ggaaauggaa      180

guucagaagu agaaguagua ccauuucaag aaguaugggg aagaucauau uguagagcac      240

uugaaagauu aguagaugua guaagugaau auccaagcga aguagaacau auguuuucac      300

caucaugugu aaguuuauua agauguacag gauguugugg agaugaaaau cuacauugug      360

uaccaguaga aacagcaaau guaacaaugc aauuacuaaa aauaagaagu ggagauagac      420

caucauaugu agaauuaaca uucagucaac auguaagaug ugaauguaga ccauuaagag      480

aaaaaaugaa accagaaaga agaagaccaa aaggaagagg aaaaagaaga agagaaaaac      540

aaagaccaac agauugccau uuauguggag augcaguacc aagaagauaa ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  4911
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt12)

<400>  4911
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagacagac aaacagauac agcaccuuca ccaagcuauc      120

acuuauuacc ugguagaaga agaacaguag augcagcagc uaguagggga caaggaccag      180

aaccagcucc aggaggaggu guagaaggag uaggggcaag aggaguagcu uuaaaauuau      240

uuguacaacu uuuaggaugu agcagguuug gaggagcggu uguaagagcc ggugaagcag      300

aaccgucagg agcagcaaga ucagcaagcu caggaaggga agaaccacaa ccagaagaag      360

gugaagaaga agaagaaaag gaagaagaaa ggggaccaca auggcgacug ggagcaagaa      420

agccagguag uuggacagga gaagcagcag uaugcgcaga cucugcacca gcagcaagag      480

caccgcaagc auuagcucga gcaaguggaa ggggaggaag aguagcucga agaggagcag      540

aagaaucagg accuccacac aguccaagua ggagaggaag ugcaagcagg gcaggaccag      600

ggagagcaag cgaaacaaug aauuuucuau ugaguugggu acauuggagc cuagcccuau      660

uauuauauuu acaucaugcu aaauggucac aagcagcacc aauggcagaa ggaggaggac      720

aaaaucauca ugagguagug aaauuuaugg auguauauca aagaucauau ugucauccaa      780

uagaaacauu aguugacaua uuucaagaau auccagauga aauagaauau aucuuuaaac      840

cuagcugugu cccauugaug agauguggag gauguuguaa ugaugaggga uuagaaugcg      900

uaccaacaga agaaaguaac auaacaaugc aaauaaugcg aauaaaacca caucaaggac      960

aacauauagg agaaauguca uuuuugcaac auaacaaaug cgaaugcagg ccaaaaaaag     1020

acagagcaag acaagaaaaa aaaaguguua gaggaaaagg aaaaggucaa aaaaggaaaa     1080

gaaaaaaaag uagauauaaa aguuggagug uauauguagg agcaagaugu uguuuaaugc     1140

cauggagucu accgggacca cauccaugug gaccuugcag ugagaggaga aaacacuuau     1200

uuguucaaga cccacaaaca uguaaauguu cuuguaaaaa cacugauagc agauguaaag     1260

cucgacaauu ggaauuaaau gaaaggacau guagauguga uaaaccaaga agauaaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  4912
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt12)

<400>  4912
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuau uaagcugggu acacugguca cuagcauuau      120

uauuauauuu acaucacgcc aaauggucac aagcagcacc aauggcagaa ggaggaggac      180

aaaaccacca cgaaguagua aaauuuaugg auguauacca aagaagcuau ugccauccaa      240

uagaaacacu aguagacaua uuccaagaau auccagauga aauagaauau auauuuaaac      300

cauccugcgu accauuaaug agaugcggag gaugcugcaa cgacgaagga cuagaaugcg      360

uaccaacaga agaaaguaau auaacaaugc aaauaaugag aauaaaacca caccaaggac      420

aacacauagg cgaaaugagu uucuuacaac auaacaaaug cgaaugcaga ccaaaaaaag      480

acagagcaag acaagaaaaa aaaagcguaa gaggaaaagg aaaaggacaa aaaagaaaaa      540

gaaaaaaaag cagauacaaa agcuggagcg uauacguagg agcaagaugc ugcuuaaugc      600

cauggucacu accaggacca cacccaugcg gaccauguuc agaaagaaga aaacaucuau      660

uuguacaaga cccacaaaca uguaaaugcu caugcaaaaa caccgacagu agauguaaag      720

caagacaacu agaacuaaau gaaagaaccu guagauguga caaaccaaga agauaaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  4913
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt12)

<400>  4913
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaccacuau uaagaagacu acuauuagca gcauuacuac      120

aacuagcacc agcacaagcu ccaguaagcc aaccagacgc acccggacau caaagaaaag      180

uaguaucaug gauagaugua uacacaagag caacauguca accaagagaa guuguagucc      240

cacuaacagu agaauuaaug ggaacaguag caaaacaauu aguaccauca ugcguaaccg      300

uacaaagaug cggaggaugu ugcccagacg auggcuuaga augcguacca acuggacaac      360

aucaaguaag aaugcaaaua cuaaugauaa gauacccauc aucacaauua ggagaaaugu      420

cauuagaaga acauucacaa ugcgaaugca gaccaaaaaa aaaagacuca gcaguaaaac      480

cagacagagc agcaacacca caucauagac cacaaccaag aucaguacca ggaugggacu      540

cagcaccagg agcaccaucu ccagcagaca uaacacaucc aacaccagca ccaggaccau      600

cagcacaugc agcacccuca acaacaagug cacuaacacc aggaccagca gcagcagcag      660

cugacgcagc agcaucauca gucgcaaaag gaggagccua aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  4914
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt12)

<400>  4914
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuauuag gauucuuuag cguagcgugc aguuuauugg      120

cagcagcacu auuaccaggu ccacgugaag caccagccgc agccgcagcu uucgaaucag      180

gauuagacuu aagcgacgcu gaacccgacg caggcgaagc aacagcauac gcuucaaaag      240

aucuagaaga acaacuaaga ucuguaucuu caguagacga auuaaugaca guacuauacc      300

cagaauauug gaaaauguau aaaugccaac uaagaaaagg agguuggcaa cacaauagag      360

aacaagcaaa cuuaaacucc agaacagaag agacuauaaa auuugcagca gcacauuaca      420

acacagaaau ucuaaaauca auagacaaug aauggagaaa aacucaaugu augccaagag      480

aaguaugcau agacguaggu aaagaauucg guguagccac caacacauuu uuuaaaccac      540

caugcguauc aguauauaga ugcggaggcu guugcaauuc agaaggauua caauguauga      600

auaccucuac aagcuaccua ucaaaaacac uauucgaaau aacuguacca uuaucacaag      660

gaccaaaacc aguaacaaua ucauuugcaa accacacauc augucgaugc augucaaaau      720

uagacguaua ccgacaagua cacaguauaa uaagaagauc acuacccgca acacuaccac      780

aaugccaagc agcaaauaaa acaugcccaa cuaacuacau guggaauaau cauauuugua      840

gaugccuagc acaagaagau uucauguucu caagugaugc aggugacgac ucuacugacg      900

gauuucauga cauaugugga ccaaauaaag aacuagacga agaaacaugu caaugcguau      960

gcagagcagg acuucgacca gcauccugug guccacauaa agaacuagau agaaauucau     1020

gccaaugugu uuguaaaaau aaauuauucc ccagccaaug cggagcaaau agagaauuug     1080

augaaaauac augccaaugu guauguaaaa gaaccugccc aagaaaucaa ccacuaaacc     1140

caggaaaaug cgccugcgaa ugcacagaaa guccacaaaa augucuauua aaagguaaaa     1200

aauuccauca ccaaacaugu ucaugcuaca gaagaccaug cacaaacaga caaaaagcau     1260

gugaaccugg auuuucauau ucagaagaag uuuguagaug uguuccauca uacuggaaac     1320

gaccacaaau gagcuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  4915
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt12)

<400>  4915
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagaau ggguaguagu aaacguauuc augaugcuau      120

auguacaacu uguacaagga agcucaaaug aacacggacc aguaaaaaga ucaucacagu      180

ccacacuaga aagaucagaa caacaaauaa gagcagcauc cucucuagaa gaauuacuaa      240

gaaucacaca uuccgaagac uggaaauuau ggcgaugucg acuacgcuua aaaagcuuua      300

cuaguaugga cucacgcuca gcaucacaua gaaguacaag auuugcagca acauucuacg      360

acauagaaac acuaaaagua auagaugaag aauggcaaag aacacaaugc ucaccaagag      420

aaacaugcgu cgaaguagca ucugaacucg gaaaauccac caauacauuc uucaaaccac      480

caugcguuaa cguauuuaga ugcggaggau guugcaacga agaaucacua auaugcauga      540

auacauccac aucauacaua ucaaaacaac uauucgaaau auccguacca uuaacaucag      600

uaccagaacu aguaccagua aaaguagcaa aucacacagg augcaaaugc cuaccaacag      660

caccaagaca cccuuacagc auaauaagaa gaucaauaca aauacccgaa gaagacagau      720

gcucccacag caaaaaauua ugcccaaucg acaugcuaug ggacucaaac aaaugcaaau      780

gcguacuaca agaagaaaac ccacuagcag guacagaaga ccacucacac cuacaagaac      840

cagcauuaug cgguccucac augauguucg acgaagauag augcgaaugc guaugcaaaa      900

caccaugucc aaaagacuua auacaacacc caaaaaauug cuccuguuuu gaauguaaag      960

aaucacuaga aacaugcugc caaaaacaca aauuauuuca ucccgauaca ugcucaugcg     1020

aagacagaug cccauuccac acaagaccau gcgcaagugg aaaaacagcc ugcgccaagc     1080

acugccgauu cccaaaagaa aaaagagcag cucaaggacc acacucacga aaaaauccau     1140

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  4916
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt13)

<400>  4916
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucagacg aaacagguuu cgaacacucc ggauuauggg      120

uaucaguauu agcaggauua cuauuaggag caugccaagc acauccaaua ccagacucau      180

caccacuucu acaauucgga ggacaaguaa gacaaagaua cuuauacaca gaugacgccc      240

aacaaacaga agcacacuua gaaauaagag aagacggcac agucggagga gcagcagacc      300

aaucaccaga aucuuuauua caauuaaaag cauuaaaacc aggaguaaua caaauauuag      360

gaguaaaaac aucaagauuu cuaugccaaa gaccagacgg agcauuauac ggaucauuac      420

auuucgaccc agaagcaugu ucauucagag aauuauuacu agaagauggu uauaauguau      480

aucaaucuga agcacacgga uuaccacuac aucuaccagg aaauaaauca ccacauagag      540

acccagcacc aagaggacca gcaagauucu uaccauuacc cggauuaccu ccagcacuac      600

cugaaccacc aggaauacua gcaccacaac caccagaugu aggaucaucc gacccauuau      660

caaugguagg accaucacaa ggaagaaguc caucauacgc aucauaagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  4917
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt13)

<400>  4917
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacucauucc cuccacuauu auuauuacua uuuuggggag      120

uaguaucaca caguuucccu gcaaccuuag aaacacaaga acaagacgua gaccuaguuc      180

aaaaauacuu ggaaaaauac uacaaccuua aaaaugacgg aagacaagua gaaaaacgaa      240

gaaauucagg accagucgua gaaaaacuaa aacaaaugca agaauuuuuc ggacuaaaag      300

uuacaggaaa accagaugca gaaacacuaa aaguaaugaa acaaccuaga uguggaguac      360

ccgacguagc ccaauuugua uuaacagaag gcaacccaag augggaacaa acccacuuaa      420

ccuacagaau agaaaauuac acaccagauc uaccuagagc cgacguagau caugcgauag      480

aaaaagcauu ucaauuaugg aguaauguaa cuccacuaac auuuacaaaa gucucagaag      540

gacaagcgga cauaaugaua uccuucguaa gaggagauca cagagacaau aguccauucg      600

acggaccagg cggaaaccua gcacacgcuu uccaaccagg acccggcaua ggaggagaug      660

cacacuucga cgaagacgaa agauggacaa acaacuucag agaauauaac cuccacagag      720

uagcugcaca ugaacuagga cauucauuag gacuuagcca cagcacagac auaggagcac      780

uaauguaccc uucauauaca uuuucaggag acguacaauu agcacaagac gauauagacg      840

gaauacaagc aauauaugga agaucacaaa auccuguaca accgaucgga ccucagacac      900

caaaagcaug cgauagcaaa cuuaccuucg acgcuauaac aacaauuaga ggcgaaguaa      960

uguucuucaa agaccgauuu uacaugagaa caaauccauu cuaucccgaa guagaauuaa     1020

acuuuauauc cguauuuugg ccacaacucc cuaacggauu agaagccgca uacgaauuug     1080

cagauagaga cgaaguaaga uuuuucaaag gaaacaaaua cugggcugua caaggacaaa     1140

acguacuaca cggauaucca aaagacauau acucaucauu cggcuuuccc cgaacaguaa     1200

aacauauaga ugcagcauua ucagaagaaa acacaggaaa aacauauuuc uuuguagcca     1260

acaaauacug gagauaugau gaauacaaaa gaucaaugga cccagguuac ccaaaaauga     1320

uagcacauga uuuuccagga auuggacaua aagucgacgc cgucuucaug aaagacggau     1380

ucuucuauuu cuuucaugga acuagacaau auaaauucga cccaaaaaca aaaagaauau     1440

uaacacuaca aaaagcaaac ucuugguuca acuguaggaa aaauuaagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  4918
<211>  1517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt13)

<400>  4918
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacucauuuc caccauuacu acucuuauua uuuuggggag      120

uaguaucaca cucauucgua cuaacagaag gaaauccaag augggaacaa acacaccuua      180

ccuacagaau agaaaauuac acaccagauc uaccaagagc agacguagac cacgcaauag      240

aaaaagcauu ucaauuaugg ucaaacguaa caccauuaac auucacaaaa guaucagaag      300

gacaagcaga cauaaugaua ucauucguaa gaggagacca cagagacaau ucaccauuug      360

auggaccagg agguaaucug gcacacgcau uccaaccagg accaggaaua ggaggagacg      420

cacacuucga cgaagacgaa agauggacaa acaacuucag agaauacaac cuacacagag      480

uagcagccca ugaacuagga cacucacuag gacuaucaca cucaacagac auaggagccc      540

uaauguaucc auccuacaca uucucaggag acguacaacu cgcgcaagac gacauugacg      600

gaauccaagc uauauacgga agaucacaaa acccaguaca accaauaggc ccccaaacac      660

caaaagcaug ugacucaaaa cuaacauuug augcaauaac aacaauaaga ggcgaaguaa      720

uguucuucaa agacagauuc uacaugcgca caaauccauu cuacccagaa gucgaauuaa      780

acuucauauc aguauucugg ccccaauuac caaacggauu agaagccgcc uacgaauuug      840

cagaccgaga cgaaguaaga uucuucaaag gaaacaaaua uugggcagua caaggacaaa      900

acguauuaca cggauaucca aaagacauau acuccucauu uggcuuucca agaacaguaa      960

aacauaucga cgcagcacuc uccgaagaaa acacaggaaa aacauacuuc uuuguagcaa     1020

acaaauacug gagauaugac gaauauaaaa gaucaaugga cccgggauac ccaaaaauga     1080

uagcacauga cuucccagga auaggacaca aaguagacgc cguauucaug aaagacggau     1140

uuuucuacuu cuuucacgga acuagacaau acaaauucga cccaaaaaca aaaaggauac     1200

uaacauuaca aaaagcaaac ucaugguuua acugccgcaa aaacuaagga cuagugcauc     1260

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1320

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1380

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1440

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aagaauu                                                    1517


<210>  4919
<211>  3704
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt13)

<400>  4919
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaaaaaua uacuuaaaau acucauggac ucauacagua      120

aagaaagcaa aauucaaacg guucgaagag uaaccagugu cagccuauua gcaguauauc      180

uaacuaugaa uacuagcagc uuaguacucg cgaaaccaau ugaaaauaca aaugacacaa      240

guauuaaaaa uguagaaaaa uugagaaaug caccaaauga agaaaacucg aagaaaguag      300

aagauagcaa aaaugauaaa guugagcaug uuaaaaacau agaagaagca aaagucgaac      360

agguggcucc agaaguaaaa ucaaaaagca cacucagauc agcaaguauc gcaaacacga      420

acagugagaa auaugauuuu gaauaccuga auggccucuc auauacagaa uuaacaaacu      480

uaauuaaaaa uauaaaaugg aaucaaauca acggcuuauu caauuacagu accggaaguc      540

agaaauucuu uggggacaaa aaccgaguac aagcaauaau uaaugcauua caagaaucag      600

ggcgaacaua uacagccaac gauaugaaag gaauugaaac auucaccgag guuuuacgag      660

cuggcuucua uuugggcuac uacaacgaug gacuauccua uuugaacgau agaaacuuuc      720

aggauaaaug uauaccagca augaucgcaa uacagaagaa cccaaacuuc aaauuaggaa      780

cagcaguaca agaugaagua auuaccaguc uugguaaauu aauuggaaac gcaagcgcga      840

augcugaagu uguaaauaac ugugucccag ucuuaaaaca auuuagagag aauuuaaauc      900

aauaugcacc agauuacguu aaaggaacag cgguuaauga auuaauaaaa ggaauagagu      960

ucgacuuuag cggagcagcu uacgaaaaag acguaaaaac uaugccuugg uacggaaaga     1020

uugauccauu cauaaacgaa uuaaaagcau ugggccucua cggaaauaua acaucagcua     1080

cagaaugggc cagcgaugug gguauauacu aucuuaguaa auucggucuu uauaguacaa     1140

acaggaauga uaucguucaa ucacuagaaa aagcaguaga uauguauaaa uacggaaaaa     1200

uagcauuugu ggcaauggaa agaauaacau gggacuauga uggaauagga ucuaacggca     1260

agaaaguaga ccaugacaaa uuucucgacg augccgaaaa acacuacuua ccaaaaacgu     1320

auacauuuga caauggaaca uuuaucauaa gagcggguga caaaguaagu gaagagaaaa     1380

uaaaaagacu auacugggca ucuagagaag uaaaaucuca auuucacagg gucgucggga     1440

augacaaagc acuagaagua ggaaacgccg acgauguccu cacaaugaaa auauucaaca     1500

gccccgaaga auauaaauuc aauacuaaua uaaauggagu uagcacagac aauggcggau     1560

uauauauaga accacgaggg acuuucuaca cguaugaaag aacaccacaa caaucaauau     1620

ucagcuuaga agaacuguuu agacaugaau auacucauua cuuacaagcu cgauauuuag     1680

uggauggauu auggggacaa ggccccuucu acgagaaaaa cagacuaacu ugguucgacg     1740

aaggaacagc agaguucuuc gccggcucaa ccaggacauc aggagugcuu ccgagaaaau     1800

caauacuagg cuaucuugca aaagauaaag uagaccacag auacagccuc aagaaaacau     1860

uaaauucagg auaugaugau agcgauugga uguuuuauaa uuauggguuu gcuguagccc     1920

acuauuuaua ugaaaaagau augccaacau uuauaaaaau gaauaaagca auucuaaaua     1980

ccgacguuaa aagcuaugau gaaauaauaa agaaauuauc agacgacgcg aacaaaaaca     2040

cagaauauca aaaucacaua caagaauuag ccgacaaaua ucaaggagca ggcauacccu     2100

uagugucaga cgacuauuua aaagaucaug gauauaagaa agcguccgaa guauauucug     2160

aaauaucuaa agcggcaagc cuaacaaaua cauccguaac agcggaaaaa ucacaauacu     2220

uuaauacauu uacacuaaga ggaacauaua caggagaaac aaguaaaggc gaauuuaaag     2280

acugggacga aaugagcaag aaacuggacg gaacacuaga aagccuagcu aaaaacucau     2340

ggagcggaua uaaaacauua acggcauauu uuaccaauua ccgaguaacg uccgacaaca     2400

aaguacaaua ugacguugua uuucacggcg uuuuaacaga uaacgcagau auaaguaaua     2460

acaaagcacc aauagcaaaa guuacaggcc caucgacagg ugccguaggu agaaacauug     2520

aauuuucugg aaaagauuca aaagaugaag auggaaaaau cguaucauac gacugggacu     2580

uuggagacgg agcaacauca agagggaaaa auucagucca ugcauacaag aaagcuggaa     2640

cauauaacgu aacauuaaaa guuaccgaug auaaaggugc gacagcaacu gaaucuuuua     2700

caaucgaaau caaaaacgaa gauacaacaa caccaauaac gaaagaaaug gaacccaaug     2760

acgauauaaa agaagcuaau ggaccaauag ucgaaggagu aaccgucaaa ggugaccuaa     2820

acggcuccga cgacgcugau acauucuauu uugauguuaa agaagaugga gaugugacaa     2880

uagaacuacc auauucagga ucuaguaacu uuaccuggcu gguauauaaa gaaggcgaug     2940

aucaaaauca uaucgcuagu gguauagaca aaaauaacag caaaguugga acauuuaaaa     3000

gcacaaaagg uagacauuac guauucauuu acaaacacga uucagcauca aauaucucau     3060

acucuuuaaa uauaaaaggc uuagguaaug aaaaacugaa agagaaagaa aauaaugauu     3120

cgucagacaa agcuacagug auaccaaauu ucaauacaac uaugcaagga ucacugcuag     3180

gagaugacag ccgugauuau uacagcuucg aaguaaaaga agaaggagag guaaacaucg     3240

aauuagauaa gaaagaugaa uuuggaguaa cauggacauu acauccagaa uccaacauaa     3300

acgacagaau aacauacgga caaguugaug guaacaaagu aaguaauaaa guaaaauuga     3360

ggccuggaaa auacuaccug uuaguauaua aauacagugg gucaggaaac uacgaacuac     3420

gaguuaacaa auaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3480

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3540

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3600

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      3704


<210>  4920
<211>  3428
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt13)

<400>  4920
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguaa cuuuuauaag ucuucuauuu cuauuuucau      120

cggcauauag uauagcaaac acaaacucag aaaaauauga cuuugaauau cuaaauggau      180

uaucauauac agaauuaaca aaccugauca aaaacauaaa auggaaucaa auaaacggau      240

uauuuaacua uagcacggga ucacagaaau uuuucggcga uaaaaauaga guacaagcaa      300

uuauaaaugc ucuccaagaa ucuggcagaa cguauacagc aaacgauaug aaaggaaucg      360

aaacuuuuac agaaguccug agagcagguu uuuacuuagg uuauuacaac gacgggcuaa      420

gcuaucuaaa ugauagaaac uuccaagaca aauguauacc agcaaugauu gcaauacaga      480

aaaaccccaa uuuuaaauua ggaacagcag uucaagacga aguuauaaca ucucuuggca      540

aacuuauagg gaacgcaagc gcaaacgcag aaguaguaaa caacugugua ccgguauuaa      600

aacaauucag agaaaauuua aaucaauacg caccagacua uguaaaagga acagcaguaa      660

acgaacuaau aaaaggaaua gaauuugauu ucagcggagc cgcauaugaa aaggauguca      720

aaacuaugcc gugguacgga aaaauagacc cauuuauaaa ugaacuuaaa gcacuagguu      780

uauacggaaa caucacaagc gcaacugaau gggcaucaga uguuggaauu uauuaccuau      840

cuaaauuugg acuauacuca accaacagga acgauauagu gcaaucucug gaaaaagcug      900

uagacaugua uaaauaugga aaaauagcuu ucgucgcaau ggaaagaaua acuugggauu      960

augaugguau uggaucaaac ggcaaaaagg uagaucacga uaaauucuua gaugacgcag     1020

aaaagcacua cuuaccaaaa acguauacau ucgacaacgg gacuuuuaua aucagagcag     1080

gcgauaaagu auccgaagag aaaauaaaaa gauuauacug ggcuucaagg gaaguaaaau     1140

cucaauucca ccgaguagua ggaaaugaua aagcauuaga aguggguaac gcugaugaug     1200

uauuaacaau gaaaauauuc aacagcccug aagaauacaa guucaauaca aauauaaacg     1260

gagucucuac cgauaacgga ggcuuauaca uugaaccaag aggaacauuu uacacauaug     1320

aaagaacucc acaacaaagc auauucagcc uugaggaacu auuccgacac gaauauacac     1380

auuacuuaca agccagguau cuuguagaug gacuuugggg acagggaccu uucuaugaaa     1440

agaauagacu aaccugguuc gacgaaggaa cagcagaguu cuuugcaggu ucaacaagaa     1500

caucuggagu auuaccacga aaaucaauuc ucgguuauuu agcaaaagau aaaguagauc     1560

auagauauuc acuaaagaaa accuugaacu caggauacga cgacagugac uggauguucu     1620

acaauuacgg auuugcagua gcacacuauu uauaugaaaa agauaugccu acauucauua     1680

aaaugaacaa agcaauacua aauaccgaug ugaaaagcua ugacgaaaua auaaagaaac     1740

uuucagacga ugcgaacaaa aauacagaau accaaaacca uauucaagaa cucgccgaca     1800

aauaccaagg ugcaggcauu ccucuaguaa gugacgacua uuuaaaagac cauggauaca     1860

agaaagcauc agaagucuau ucagaaauca gcaaagccgc auccuuaacu aauacaagcg     1920

ucacagcaga gaaaucacaa uacuuuaaua cauucacgcu ucgaggaacu uauacaggug     1980

aaacgucaaa aggagaguuu aaagauuggg augaaauguc aaagaaauua gauggaacac     2040

uagaaucguu agcuaaaaac ucauggucug gauauaaaac acuaaccgca uacuuuacua     2100

acuacagagu uaccagugau aacaaaguac aauacgaugu aguauuucau ggaguacuaa     2160

cagacaaugc agacauuagc aauaacaaag caccaauagc aaaaguuacc ggccccucaa     2220

caggggcagu agguagaaau auugaguucu cuggaaaaga uagcaaagau gaagauggaa     2280

aaauaguuuc auaugauugg gacuuuggug auggagcaac uagcaggggc aaaaacucag     2340

uucacgcaua caagaaagca ggaacauaua acguaaccuu aaaaguaacc gaugauaaag     2400

gagcaaccgc caccgaaagu uuuacuauag aaaucaaaaa cgaagacaca acgacaccaa     2460

uaacaaaaga aauggaacca aaugacgaca uaaaagaagc aaacggacca auaguagaag     2520

gaguaacagu aaaaggagac cuaaauggcu cggacgaugc agauacauuu uacuuugaug     2580

ucaaagagga uggugacgua accauagaac uacccuauag cggaucaagu aauuucacuu     2640

ggcuaguuua caaagaagga gaugaccaaa accauauugc aucaggaauu gauaaaaaca     2700

acucaaaagu aggcacauuc aaaucaacaa aaggacgaca uuacguuuuc auauauaaac     2760

acgacagcgc uucaaacaua ucauauucuc ucaacauaaa agguuuaggc aaugaaaaau     2820

uaaaagaaaa agaaaauaac gacucaucag auaaagcaac cguaauccca aauuucaaua     2880

caacgaugca aggaucgcuc cucggagaug acagucguga uuacuacuca uuugaaguaa     2940

aagaagaagg agaaguuaau auagaacuag auaagaaaga cgaguucgga guaacaugga     3000

cauuacaccc agagaguaau aucaacgaua gaauuacaua uggccaaguu gacggaaaua     3060

aaguuaguaa uaaaguaaaa cuuaggccag gaaaauauua ccugcucguc uacaaauacu     3120

cagguagcgg uaacuaugaa cuaagaguaa acaaauaagg acuagugcau cacauuuaaa     3180

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3240

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3300

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaagaauu                                                              3428


<210>  4921
<211>  3776
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt13)

<400>  4921
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguaa cauucauuag ccucuuauuu cuauuuucau      120

cagcauacag uaugaagaaa aauauacuaa aaauauugau ggacuccuau aguaaagaga      180

gcaaaauaca aacaguaagg cgaguaacca gcgugaguuu acuugcugua uaucuaacaa      240

ugaacacaag uagccuaguu uuagcaaaac caauagaaaa uacgaaugau accuccauca      300

aaaacguaga aaaacuaaga aaugcaccaa acgaagaaaa uucaaagaaa guagaagaua      360

guaaaaacga caaaguagaa caugugaaaa acauagaaga agccaaagua gaacaaguag      420

caccagaagu caaaucuaaa uccacuuuaa gaagugcguc aaggagaaga agaaaaagaa      480

uagcaaacac aaauagugaa aaauacgauu ucgaauaccu aaacggacua uccuauacug      540

aacuaacaaa ucuaauuaaa aacauaaaau ggaaucaaau aaacgguuua uuuaacuauu      600

ccacaggcuc acaaaaauuu uucggagaua aaaaucgcgu ucaagcaaua auaaaugccc      660

uacaagaaag cgggagaacc uacaccgcaa augauaugaa aggaauagaa acauucacag      720

aaguacuuag agccgguuuc uaucuagguu acuauaacga cggauuaagu uaucuaaaug      780

auaggaacuu ccaagauaaa ugcauaccag caaugaucgc aauacagaaa aauccaaauu      840

ucaaauuggg aacagcaguc caagacgaag ugauaacauc acuaggaaaa cuaauaggca      900

acgcaagugc aaacgccgaa guaguaaaca acuguguucc aguacuaaaa caauucagag      960

aaaaccuaaa ccaauacgca ccugauuaug uuaaagguac agccgucaac gaacucauaa     1020

aagguauaga guucgacuuc ucaggagcag cguacgaaaa agauguaaaa acaaugccau     1080

gguauggaaa aauugaucca uuuauuaaug aauuaaaggc auuaggauug uacggaaaca     1140

uaaccucggc uacagaaugg gcaucagaug uaggaauaua cuaccuuuca aaauuugguc     1200

uauauagcac aaaccggaac gauauaguac aaucauuaga aaaagccgua gacauguaua     1260

aauauggaaa aauagcauuu gucgcaaugg aaagaauaac cugggacuac gacggaauag     1320

ggucuaacgg gaagaaagua gaccaugaua aauuucucga ugaugccgaa aaacauuauc     1380

uaccuaaaac uuacacuuuc gacaauggca cauucauaau cagagcuggc gacaaaguau     1440

ccgaagagaa aauaaaaaga uuauauuggg caucuagaga gguaaaaagu caguuucaca     1500

gagucguagg aaaugauaaa gcucuugagg uaggaaacgc agaugacgug uuaacaauga     1560

aaauauuuaa uucaccggaa gaauacaagu ucaauacaaa cauuaauggc guauccacag     1620

acaauggagg acuauauauc gaaccacgag gaacauucua uacauaugaa agaaccccac     1680

aacagaguau uuucagucua gaagaauuau uuaggcacga auacacccau uauuuacaag     1740

cacguuaucu aguagacgga cuaugggguc agggacccuu cuacgaaaag aaccgcuuaa     1800

caugguucga ugaagguacu gcggaauuuu ucgcuggauc aacacgaacc aguggaguac     1860

ucccaagaaa aucaauuuua gguuaccuug caaaagauaa agucgaucac agauacucac     1920

ucaaaaagac acuaaauuca ggauaugaug acucagacug gauguuuuau aauuauggau     1980

ucgcagucgc acacuaccuc uacgaaaaag auaugccaac guucauuaag augaauaagg     2040

caauacuaaa uacagaugua aaaucauacg acgaaaucau aaagaaacua uccgacgacg     2100

caaauaaaaa uacagaauac caaaaccaua uacaagaacu agcagacaaa uaucagggag     2160

caggcauccc acuuguaagc gacgacuacu ugaaagacca cggauacaag aaagcauccg     2220

aagucuacuc agaaauaucc aaagcagccu cauuaacaaa uacguccgua acugcugaga     2280

aaagucaaua uuucaacaca uucacacuac guggaacaua caccggcgaa acgaguaaag     2340

gagaguucaa agauugggac gaaaugucaa agaaauuaga cgguacacua gaaucauuag     2400

ccaaaaauuc auggagcgga uacaaaacuc uuacggcaua cuuuacaaac uauaggguua     2460

caagugauaa caaaguacaa uaugacguag uauuucaugg aguccucaca gacaaugcug     2520

auaucagcaa caacaaagcu ccuaucgcua aaguaacugg gcccaguacg ggagcaguag     2580

gcagaaacau ugaguucuca ggaaaagacu caaaagacga agauggcaaa auaguauccu     2640

augauuggga cuuuggagau ggagcaacau caagaggcaa aaacucaguc cacgcauaca     2700

agaaagcagg aacauauaau guaacacuua aaguaacaga cgauaaaggc gcaacagcaa     2760

cagaaucauu cacaauagaa auuaaaaacg aagauacaac aacaccaaua acaaaagaaa     2820

uggaaccaaa cgaugauaua aaagaggcaa acgguccaau aguggaagga guaacaguaa     2880

aaggcgacuu gaaugggagc gacgacgccg acacauuuua uuucgacguu aaagaggacg     2940

gcgacguaac aauagaauua ccauacagug gaucaagcaa cuuuacgugg cuaguuuaua     3000

aagaaggaga cgaccaaaac cauauagcaa gugguauaga caaaaacaau aguaaaguag     3060

guacauuuaa aaguaccaaa ggcagacauu acguauuuau auacaaacac gauucagcau     3120

caaacauauc auauucucua aauauaaaag gauuagggaa ugaaaaacuu aaagaaaaag     3180

agaauaauga cagcagcgac aaagcaacug ucauacccaa cuuuaacaca acaaugcaag     3240

guucacuauu aggagacgac agucgagauu auuauagcuu cgaaguaaaa gaggaaggag     3300

aagucaauau agaauuagau aagaaagacg aauuuggagu aacauggaca cuucauccug     3360

aaaguaauau aaacgauaga auaacauacg gacaaguaga cggaaacaaa gucucaaaua     3420

aaguaaaacu uagaccaggg aaauauuauc uacuuguaua uaaauacagu ggaucaggua     3480

acuaugaacu aagagucaau aaauaaggac uagugcauca cauuuaaaag caucucagcc     3540

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     3600

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     3660

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa agaauu         3776


<210>  4922
<211>  3452
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt13)

<400>  4922
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuucuuga aaauaauccu caacagagga aaaaccauga      120

aacgaaaaug ucugucaaaa agauuaaugc uagcuauaac aauggccacc auauucacag      180

ucaacucaac acuaccaauc uaugcagcag uagauaaaaa uaaugcuaca gcugcaguac      240

aaaacgaauc aaaacguuau acaguuucgu acuuaaaaac auuaaauuau uaugaccucg      300

ucgaucuauu gguaaaaaca gaaaucgaaa auuuaccaga uuuauuccaa uacagcucag      360

augcuaaaga guucuauggu aacaaaacaa gaaugagcuu cauuauggac gaaauaggua      420

gaagggcucc acaauauaca gaaauagacc auaaaggaau accaacccua guagaaguag      480

ucagagccgg auuuuaucuu ggauuccaca acaaagaauu aaaugaaauc aacaaaagau      540

cauucaaaga acgaguaauc ccaagcauau uagcaauaca aaagaaucca aauuucaaau      600

uaggaacaga aguucaggac aaaauaguua gcgcaacagg acuucuagcc ggaaaugaaa      660

cagcaccucc ugaaguagua aauaacuuua caccaauauu gcaggauugc auaaagaaca      720

uagauagaua cgcguuagau gaccuaaaau cuaaagccuu auucaaugug cuugcagccc      780

caacauacga caucacugaa uaucuccgag ccacaaaaga aaaaccagaa aacacaccau      840

gguacgggaa aauagacgga uucauaaacg aacucaagaa acuagcauua uaugguaaaa      900

uaaacgacaa caacucaugg aucauagaca augguauaua ccauauagcc ccauuaggaa      960

aacuucacag caauaauaaa auaggaauag agacauuaac agaaguaaug aaaguauacc     1020

cuuauuuaag uaugcaacau uuacaaucag cagaccaaau caaaagacau uacgacagua     1080

aagacgcgga aggaaacaaa auuccauuag acaaauuuaa aaaggaagga aaagaaaaau     1140

auuguccaaa aaccuacaca uuugacgaug gaaaagucau uauaaaagcc ggagcacgug     1200

uagaggaaga aaaagugaaa agacuuuacu gggcauccaa agaaguaaau ucacaauucu     1260

uucgaguuua cggaauugac aaaccccugg aagaaggaaa cccagacgac auuuuaacga     1320

ugguaauaua caacaguccu gaagaauaca aacuaaacag uguacuauau ggcuacgaua     1380

cgaacaacgg aggaauguac aucgaaccag aaggaacauu cuuuacguac gaaagagaag     1440

cacaggaauc aacuuauaca cuagaggaac uauuucgaca cgaauacaca cacuaucucc     1500

aagguagaua ugcaguuccg ggacaauggg gaagaacuaa guuauacgau aaugacagac     1560

uaacauggua ugaagaagga ggggccgagu uauucgcggg caguaccaga acaaguggga     1620

uauuacccag aaaaagcauu guauccaaca uacacaacac cacgaggaau aaccgauaua     1680

aacuuucaga uacaguccau ucaaaauaug gagcaucguu ugaguucuac aauuaugcau     1740

gcauguuuau ggauuauaug uauaauaaag acaugggaau acucaacaaa uuaaaugacc     1800

uagcaaagaa caaugacgug gacggauacg acaacuacau aagagaccua ucaagcaacu     1860

acgcacuaaa ugacaaauau caagaccaca ugcaagaaag aauagauaac uaugaaaauc     1920

ucacaguacc uuucguugca gaugacuacc uaguccguca ugcauacaaa aauccgaacg     1980

aaauauauuc agaaauuuca gaaguugcua aacuuaaaga ugccaaauca gaaguaaaga     2040

aaagucaaua cuucaguacu uuuacacuac gcggaagcua cacuggagga gcuucaaaag     2100

gaaaauuaga agaccaaaaa gccaugaaca aauucauaga cgauagccuc aagaaauuag     2160

auacguauag uuggucugga uauaaaacac uaacagcgua uuuuacaaau uauaaagucg     2220

auaguagcaa cagaguaaca uacgauguag uauuucaugg auauuuacca aaugaaggag     2280

auuccaaaaa uucacucccg uauggaaaaa uaaacgguac auauaaaggg acagaaaaag     2340

agaaaauaaa auucagcuca gaaggaaguu uugacccgga cgguaaaaua guaaguuacg     2400

aaugggacuu cggugacggc aauaaaucaa acgaagaaaa uccagaacac ucuuaugaua     2460

aaguaggaac cuacacagug aaauuaaaag uaacagauga uaaaggugaa ucauccguca     2520

guacgacaac agcagaaaua aaagaucugu cagaaaacaa gcucccgguu auauauaugc     2580

auguaccaaa aagcggcgcc cuaaaucaaa aaguagucuu uuacggaaaa ggaacguaug     2640

acccagacgg aaguauagca ggauaccaau gggauuuugg ggaugguagu gacuuuagca     2700

gcgaacaaaa cccaucacau gucuacacua agaaaggcga guacacaguu acacucagag     2760

uaauggacuc aaguggacaa augucagaga aaacaaugaa aauaaaaaua acagauccag     2820

uauauccaau uggaacugaa aaagaaccaa acaauucuaa agaaacagcc ucagguccca     2880

uugucccugg cauaccugua aguggaacaa uagaaaacac cagugaccaa gacuauuucu     2940

auuuugacgu uauaacaccc ggcgaaguaa aaauagacau caacaaacuu ggauacggag     3000

gagcuacaug gguuguauau gaugaaaaca auaaugcagu aaguuaugca acugaugaug     3060

gacaaaaccu aagcggaaaa uuuaaagcag auaaacccgg acgauauuau auacacuuau     3120

auauguucaa cggaaguuau augccauauc gaauaaauau agaaggaagc guaggaagau     3180

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     3240

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     3300

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     3360

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   3452


<210>  4923
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt13)

<400>  4923
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaagaaaau guuuaagcaa aagauuaaug cuagccauua      120

caauggcaac aauuuucaca guaaauagua cauuaccaau uuacgcagcu gucgacaaaa      180

acaacgcaac ugcagcagua cagaacgaau caaaacggua uacagugagc uaccucaaaa      240

cacuaaauua uuaugaccua guagaucuac uuguaaaaac agaaauugaa aaucuaccag      300

accuauucca auacuccuca gaugcaaagg aauuuuaugg aaacaaaacg cgcaugaguu      360

ucauuaugga cgaaauagga aggagggccc cacaguacac agaaauagau cauaaaggca      420

uaccaacgcu aguagaaguc guaagagcag gauuuuaccu agguuuucac aacaaagaac      480

ucaacgaaau aaacaagcgc aguuuuaaag aaagagucau uccaucaaua uuagcgaucc      540

agaaaaaccc uaacuucaaa cuaggaacag aaguacaaga caaaauugua ucagcgacag      600

gacuacuagc aggaaaugag acagcaccac cagaaguagu aaauaauuuc acaccaauau      660

uacaagacug caucaaaaau auagaccgau acgcauugga ugacuugaaa agcaaagcau      720

uauuuaaugu acuugcggca ccaacauaug acauaacaga auaccuaaga gcuacaaagg      780

aaaaaccaga aaacacacca ugguauggaa aaauagacgg auuuauaaau gaacugaaaa      840

aguuagcacu auacgguaaa aucaaugaca acaacagcug gauaauagac aaugggaucu      900

accauauagc cccauuaggu aaacuacauu caaacaacaa aauaggaauc gaaacccuaa      960

cagaaguaau gaaaguauau ccauaccuaa gcaugcaaca cuugcaaagc gcagaccaaa     1020

uaaaaaggca cuaugacagc aaagaugcag aaggaaacaa aauaccacuc gacaaguuca     1080

agaaagaagg uaaagaaaaa uauuguccca aaacguauac guucgaugac ggaaaaguaa     1140

ucauaaaagc aggagccaga guagaagaag aaaaaguaaa aagacuuuau ugggcuucga     1200

aagaagucaa cagccaauuc uucagaguau augguaucga caaaccucua gaagaaggaa     1260

auccagauga cauucuaaca augguaauau acaacucacc ggaggaauac aaauuaaaca     1320

guguccugua cggauacgau acaaacaacg guggcaugua uauagaacca gaagguacau     1380

ucuucacuua ugaaagagaa gcucaagaaa gcaccuacac auuagaggaa uuauuuagac     1440

augaauauac ucacuauuua caaggccgau augcaguacc aggccaaugg gggcguacaa     1500

aauuauacga uaacgauaga uuaacauggu augaagaagg uggagccgaa cuauucgcag     1560

guuccaccag gacuucagga auacuaccaa ggaaaucaau uguaaguaau auacacaaua     1620

ccacacguaa caacagauac aaauuauccg acacaguaca cucaaaauac ggagcaucau     1680

ucgaguucua caauuacgca uguauguuua uggauuauau guauaauaaa gauaugggaa     1740

uccuaaacaa acuaaaugac uuagcuaaaa auaaugacgu ugacggauac gacaauuaca     1800

uaagggacuu aaguagcaac uacgcauuaa acgacaaaua ccaagaccau augcaagaaa     1860

gaauagauaa cuaugaaaau cuaacgguac cauuuguugc agacgauuau uuagucagac     1920

augcauacaa aaacccuaau gaaauauaca gugaaauauc agaaguggca aaacuaaaag     1980

acgcuaaauc ugaaguaaag aaaagccaau acuuuaguac auucacacuu cgaggcucau     2040

acacaggagg agcaagcaag gguaaacucg aagaccaaaa agcaaugaac aaauuuauag     2100

augauucacu aaagaaauua gacacauaua guuggagcgg cuauaaaaca cuaaccgcau     2160

acuuuacuaa cuauaaagua gacucaucaa accgcguaac auacgacgua guauuucacg     2220

gauaccuccc caaugaaggu gacagcaaaa acucacuacc cuaugggaaa auaaauggga     2280

cauacaaagg uaccgaaaag gagaaaauaa aauuuucuuc ugaaggcagc uucgacccag     2340

acggaaaaau agucuccuac gaaugggacu ucggugaugg aaacaaaagc aaugaagaaa     2400

auccagaaca caguuacgac aaaguaggga cuuacacugu aaaacugaaa guuacagaug     2460

acaagggcga aagcucugua aguacaacca cugccgaaau aaaagaccua ucagaaaaca     2520

aacuuccagu aauauauaug cacguuccua aaucuggagc uuugaaccaa aaaguaguuu     2580

ucuacggaaa aggcacguau gacccggaug gaucaaucgc aggcuaucaa ugggacuuug     2640

gcgauggaag ugacuuuucc agcgaacaaa acccuagcca cgucuauacu aagaaaggag     2700

aauauaccgu gacauuacga guaauggauu caucaggaca aaugucagag aaaaccauga     2760

aaauaaaaau cacugaccca guauauccaa uaggaacaga aaaagaacca aacaacagua     2820

aagaaacagc cucaggucca auaguaccug gaauaccagu cucaggcaca auagaaaaca     2880

caucagacca agacuacuuc uauuuugaug uuauaacacc aggugaaguc aaaauagaua     2940

uaaauaaauu aggauauggu ggugcaacau gggucguaua cgaugaaaac aauaacgccg     3000

uuaguuacgc aacagacgau ggucaaaacc uaucugggaa auucaaagca gauaaaccug     3060

gaagauacua uauacaucua uauauguuua acggcagcua caugccauau agaauaaaua     3120

uagaaggguc aguaggaaga uaaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  4924
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt13)

<400>  4924
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguaa cuuuuauauc auuauuauuc cuauucaguu      120

cagcauauag uguacaaaau gaaucaaaaa gguacacagu auccuaucua aaaacguuaa      180

auuauuacga uuuaguagau cuccuaguca aaacugaaau agaaaacuua ccagaccuau      240

uccaauauuc guccgaugca aaagaauuuu auggaaauaa aacccgaaug ucauucauca      300

uggacgaaau uggacgaagg gcaccgcaau acacagaaau agaucacaaa gguauuccaa      360

cccucguaga agucguaaga gcuggcuucu accuaggauu ucauaauaaa gaauuaaaug      420

aaauaaacaa aaggucauuc aaagaaagag uaauacccuc cauauuagca auacaaaaaa      480

auccuaacuu uaaacuugga acagaaguuc aagacaaaau cguuucagcg accgguuuac      540

uggcaggcaa cgaaacagca ccucccgaag ucguaaacaa cuucacacca auuuuacaag      600

auuguauaaa aaauauugau cgauacgcuu uagacgaccu uaaaagcaaa gcgcuauuca      660

acguacucgc agcaccuaca uacgauauca ccgaauaccu ucgagcuaca aaagaaaaac      720

cagaaaauac uccuugguau ggcaaaauag acggauucau aaacgaauua aaaaaauuag      780

cuuuauaugg aaaaauuaau gauaauaacu cauggauaau agacaaugga auauaucaca      840

uugcaccauu aggaaaauua cauucuaaua auaaaauagg aauagaaaca uugacagaag      900

uaaugaaagu guaccccuac cuaagcaugc aacauuuaca gucagcugau caaauuaaac      960

gacacuacga uucaaaagac gcagaaggca auaaaauccc acuugacaaa uucaaaaaag     1020

aaggaaaaga aaaauacugu ccaaaaacau auacauuuga cgacggaaaa guaauaauaa     1080

aagcuggugc aagaguagaa gaagaaaaag ucaaaagacu auauugggca agcaaagaag     1140

uaaauucaca auucuuucga guauauggaa uugacaaacc ccuagaagag ggaaacccag     1200

acgauauacu aacaauggug auauacaacu caccagaaga auauaaacua aacaguguac     1260

uauacggaua cgauacaaac aauggcggga uguacauaga accagaaggu acauucuuca     1320

cguaugaaag ggaagcacaa gaauccaccu acacacucga agaacuauuc agacaugaau     1380

acacucauua ucuacaaggc agauaugccg uaccgggaca auggggaaga acaaaauuau     1440

augacaacga cagauuaaca ugguaugaag aaggaggagc agaacuauuu gcuggcagua     1500

ccagaacaag ugggauccuu cccagaaaau caauugugag uaacauacac aacacaacga     1560

gaaauaauag auauaaacua agcgauaccg uacauaguaa auauggagcc ucguucgaau     1620

uuuauaauua ugccuguaug uucauggauu acauguauaa caaagauaug gguauauuaa     1680

auaaauuaaa cgaccucgcu aaaaauaaug auguagacgg auacgacaac uacauaagag     1740

auuuauccag caacuaugca uuaaaugaca aauaucaaga ccacaugcaa gaaagaaucg     1800

acaacuauga aaaucuuacu guaccauucg uagcagacga uuaccuaguu agacacgccu     1860

auaaaaaucc caacgaaaua uauagcgaaa uaucugaagu agcaaagcua aaagacgcaa     1920

aaagcgaagu gaaaaaauca caauacuuuu caacuuucac auugagaggc ucauacacag     1980

gaggugcaag caaaggaaaa uuagaagauc aaaaagcaau gaauaaauuu auagacgaca     2040

gucuaaaaaa auuagauaca uacucauggu cagguuacaa aacacuaacg gcauacuuca     2100

caaacuauaa aguagauucc ucaaauagag uaacauacga ugucguuuuu cauggauauc     2160

uaccuaacga aggagacagc aagaauaguc uaccauaugg aaaaauaaau ggaacguaca     2220

aaggaacuga aaaagaaaaa aucaaauucu caucagaagg caguuucgau cccgacggga     2280

aaauaguauc auacgaaugg gauuuuggag auggcaacaa aucaaacgaa gaaaacccag     2340

aacauucaua ugauaaaguc ggaaccuaca caguaaaacu aaaaguaacc gaugacaagg     2400

gagaaucauc gguuuccacc acgacagcug aaauaaaaga cuuaucagaa aacaaauuac     2460

ccguaauaua caugcacgua ccaaaaucag gcgcgcuuaa ccaaaaagug guuuucuaug     2520

gaaaaggcac auacgaucca gauggaagca ucgcaggaua ccagugggau uucggagaug     2580

guucagauuu uaguucugaa caaaauccua gccauguaua caccaaaaaa ggugaauaca     2640

caguuacacu uaggguuaug gacuccucag gacaaaugag cgaaaaaaca augaaaauaa     2700

aaauaaccga cccaguauac ccaauaggaa ccgaaaagga accaaacaau ucuaaagaaa     2760

cagcaucagg uccaauagua ccaggaaucc cagugucagg gacaauagaa aacacaucag     2820

accaagacua uuucuauuuc gacguaauaa cacccggaga aguaaaaaua gacauaaaca     2880

aauuaggaua cgguggcgcc acuuggguug uauaugacga aaacaacaac gcaguaucuu     2940

augcaacuga cgacggccaa aacuuaagug gaaaguuuaa agccgauaaa ccuggacgau     3000

acuacauaca ccuauacaug uucaacggca guuacaugcc auacagaaua aacauagaag     3060

guagcguugg ucgauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4925
<211>  3485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt13)

<400>  4925
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguaa cauucaucag cuuacuauuu uuauuuucau      120

cugccuauuc caugaaaaga aaaugucuau caaaaagauu aauguuagca auaacaaugg      180

cuacaauauu cacggucaac aguacacucc caauauacgc ugcagucgac aaaaacaacg      240

cgacugcagc acgcaggcgc agaaaaagag uacagaauga aucaaaacga uacaccgugu      300

cguaccuaaa aacccuaaau uacuacgacc ucguugaccu auuaguaaaa acagaaauag      360

aaaauuuacc agaccuuuuu caauacucaa gcgaugccaa ggaauuuuac ggaaauaaaa      420

caaggaugag uuucauaaug gaugagaucg gccgccgagc accacaauau accgaaauag      480

aucauaaagg aaucccgacg uugguugaag uuguuagagc aggauucuau uuggguuuuc      540

acaacaaaga acuaaaugaa auaaauaaac gcagcuucaa agaaagagua auaccaagca      600

ucuuagcgau ucagaaaaau ccuaauuuca aacuaggaac ggaaguacaa gacaaaaucg      660

ucucagcaac gggauuguua gcgggaaacg aaaccgcucc accagaaguc guaaacaacu      720

uuacccccau acuacaagac ugcaucaaaa auauagauag auacgcauua gaugauuuaa      780

aaucuaaagc auuauucaac guauuggcgg caccaacaua ugauauaaca gaauauuuaa      840

gagcgacaaa agaaaaacca gaaaacacuc caugguaugg caaaauugac ggauuuauaa      900

augaauuaaa gaaauuggcc cuauacggaa aaauaaauga caauaacagc uggaucauug      960

acaacggaau auaccacaua gcucccuuag gaaaacuaca uaguaacaau aaaaucggua     1020

uagaaacauu aacugaagua augaaaguuu acccauaucu aaguaugcaa cauuuacaau     1080

cagcagauca aauaaaaagg cacuaugaua gcaaagacgc agagggaaac aaaauaccac     1140

uagacaaauu uaagaaagag ggaaaagaaa aauacugucc aaaaaccuac acauucgaug     1200

acggaaaagu aaucauaaaa gcaggagcaa gaguagaaga ggaaaaagua aaacgauuau     1260

auugggcauc uaaagaaguu aauucucaau ucuucagagu auacggaaua gacaaaccac     1320

uagaagaagg caauccagac gacauauuaa caaugguaau uuacaacagu ccugaagaau     1380

auaaauuaaa uucaguauua uauggauacg acacaaacaa uggaggaaug uacaucgaac     1440

ccgaaggcac auucuuuacc uacgaaagag aggcucaaga aucuacuuau acucucgaag     1500

aacuuuuuag gcaugaauau acacacuauc uccaagguag auaugccgua ccaggacaau     1560

gggguagaac aaaacuauac gauaaugaca gacuuacuug guaugaagaa ggaggcgcag     1620

aacuauuugc gggcagcaca cguacuucag gcauccuacc acgaaaaucc auaguuucca     1680

acauccacaa uacaacaaga aacaaccgau auaaauuauc agauacuguc cacucaaaau     1740

acggugcguc cuucgaauuu uacaacuacg cauguauguu uauggacuac auguauaaua     1800

aagauauggg uauacuuaac aaauugaaug acuuagccaa aaauaaugau guagacggau     1860

acgauaacua cauaagagac cuaucaucaa acuaugcauu aaaugacaaa uaucaagacc     1920

auaugcaaga aagaauugau aacuacgaaa acuuaacugu accauucgua gcagaugauu     1980

acuuaguaag acaugcauau aaaaauccaa acgaaaucua cagcgaaauc agcgaaguag     2040

ccaaacucaa agaugccaaa uccgaaguga agaaaucaca auacuucuca acauucacuu     2100

uaagagguag uuacacagga ggugcaucca aaggaaaauu agaagaccaa aaagccauga     2160

auaaauuuau agacgacagu cuaaagaaau uagauaccua cucauggagu ggauacaaaa     2220

cauuaacagc cuacuucaca aacuacaaag uagauucauc uaaccgaguc accuacgacg     2280

uaguauuuca uggcuacuua ccaaacgaag gcgauagcaa aaacucacua ccguacggca     2340

aaauuaacgg cacauacaaa ggaacagaaa aagagaaaau caaauucucc uccgaaggua     2400

gcuucgaccc agacgguaaa aucguaaguu augaauggga uuucggugac ggcaacaaau     2460

cgaacgaaga aaacccagaa cacagcuaug auaaaguagg uacauauaca gucaaacuaa     2520

aaguaaccga ugauaaaggu gaaucgucug ucucaacgac cacagccgaa auaaaagauu     2580

uguccgaaaa uaaauuacca gucaucuaua ugcauguccc aaaaucagga gcccuaaacc     2640

aaaaaguggu uuucuaugga aaaggaacau acgacccuga uggaucaaua gcaggcuauc     2700

aaugggauuu cggugacggc ucagacuuua gcagugaaca aaauccaucg cauguguaca     2760

caaagaaagg agaauacaca guaacacuac gagucaugga uucuuccgga caaaugagug     2820

agaaaacgau gaaaauuaaa auaacagacc caguauaccc aauaggaaca gaaaaagaac     2880

caaauaacuc caaagaaacc gcaucuggac caauaguccc cggaauacca guaagcggca     2940

cuaucgaaaa uacaucagac caagacuauu uuuacuuuga cguaauaacc ccaggagaag     3000

uaaaaauaga cauaaauaaa uuaggauacg gcggcgcuac auggguaguu uacgacgaaa     3060

acaacaaugc aguaucauac gcaacagaug acggacaaaa cuuaagugga aaauuuaaag     3120

cugacaaacc aggaagauau uacauacauu uauauauguu caauggaucc uauaugccau     3180

acagaaucaa cauagaagga agcguaggaa gguaaggacu agugcaucac auuuaaaagc     3240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     3300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     3360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     3420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3480

gaauu                                                                 3485


<210>  4926
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt13)

<400>  4926
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uauuauucgc augccuacua ggagcagcau      120

ucgcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaucaa uacgaccccc auacccauca uacggauaug      240

aacccauggg aggauggcua caccaccaaa uaauaccagu acuaucacaa caacaucccc      300

caacacacac auuacaaccu caccaccaca uaccaguagu accagcacaa caaccaguaa      360

uaccacaaca accaaugaug ccaguaccag gacaacacuc aaugacacca auacaacacc      420

accaaccaaa ccuaccacca ccagcccaac aaccauacca accacaacca guacaaccac      480

aaccacacca accaaugcaa ccacaaccac caguacaccc aaugcaacca cuaccaccac      540

aaccaccacu accaccaaug uucccaaugc aaccacuacc accaaugcua ccagaccuaa      600

cacucgaagc auggccauca accgauaaaa caaaaagaga agaaguagac uaaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  4927
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt13)

<400>  4927
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca ccauacccau      180

cauacggaua cgaaccaaug ggaggauggu aaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  4928
<211>  515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt13)

<400>  4928
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca ccaccaaugc      180

uaccagaccu aacacuagaa gcauggccau caacagacaa aacaaaaaga gaagaaguag      240

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      300

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      360

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      420

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 515


<210>  4929
<211>  554
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt13)

<400>  4929
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa ucaauaagac      240

caccauaccc aucauacgga uacgaaccaa ugggaggaug guaaggacua gugcaucaca      300

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      360

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      420

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      480

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaag aauu                                                        554


<210>  4930
<211>  587
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt13)

<400>  4930
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa ucaauaagac      240

caccaccaau gcuaccagac cuaacacuag aagcauggcc aucaacagac aaaacaaaaa      300

gagaagaagu agacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      360

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      420

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      480

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    587


<210>  4931
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt13)

<400>  4931
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuagua ggagccgcau      120

ucgcaaugcc acuaccacca cauccaggac acccaggaua uauaaacuuc ucauacgaag      180

uauuaacacc acucaaaugg uaccaaucca ugauaagacc cccauacuca ucauacggau      240

acgaaccaau gggcggaugg cuacaccacc aaauaauccc aguaguaucc caacaacacc      300

cacuaacaca cacauuacaa ucacaccacc acauaccagu aguaccagca caacaaccaa      360

gaguaagaca acaagcauua augccaguac caggacaaca aucaaugaca ccaacacaac      420

accaccaacc aaaccuacca cuaccagcac aacaacccuu ccaaccucaa ccaguacaac      480

cacaaccaca ccaaccaaug caaccacaac caccaguaca accaaugcaa ccacuauuac      540

cacaaccacc acuaccaccc auguucccac uaagaccauu accaccaaua cuaccagacc      600

uacaccuaga agccuggcca gcaacagaca aaacaaaaca agaagaaguc gacuaaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  4932
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt13)

<400>  4932
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aaugauaaga ccaccauacu      180

caucauacgg auacgaacca augggaggau gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4933
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt13)

<400>  4933
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aaugauaaga ccaccaccaa      180

uacuaccaga ccuacaccua gaagcauggc cagcaacaga caaaacaaaa caagaagaag      240

uagacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4934
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt13)

<400>  4934
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauauauaaa uuucucauac gaaguacuaa caccacuaaa augguaucaa ucaaugauaa      240

gaccaccaua cucaucauac ggauacgaac caaugggagg augguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4935
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt13)

<400>  4935
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaucaa ucaaugauaa      240

gaccaccacc aauacuacca gaccuacacc uagaagcaug gccagcaaca gacaaaacaa      300

aacaagaaga aguagacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4936
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt13)

<400>  4936
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac auccaggaua cauaaacuuc ucauacgaag      180

uacucacacc auuaaaaugg uaccaaaaca ugauaagaca cccauacaca ucauacggau      240

acgaaccaau gggcggaugg cuacaccacc aaauaauacc aguaguauca caacaaaccc      300

cacaaucaca cgcauuacaa ccacaccacc auauaccaau gguaccagca caacaaccag      360

gaauaccaca acaaccaaug augccacuac caggacaaca cucaaugaca ccaacccaac      420

accaccaacc aaaccuaccc cuacccgcac aacaaccauu ccaaccacaa ccaguacaac      480

cccaaccaca ccaacccuua caaccacaau caccaaugca cccaauacaa ccacuacucc      540

cacaaccacc acuaccacca auguucucaa ugcaaucacu acuaccagac cuaccauuag      600

aagcauggcc agcaacagac aaaacaaaaa gagaagaagu agacuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4937
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt13)

<400>  4937
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa uaugauaaga cacccauaca      180

caucauacgg auacgaacca augggaggau gguaaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  4938
<211>  518
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt13)

<400>  4938
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa caugauaaga cacccaucac      180

uacuaccaga ccuaccauua gaagcauggc cagcaacaga caaaacaaaa agagaagaag      240

uagacuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      300

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      360

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      420

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                              518


<210>  4939
<211>  557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt13)

<400>  4939
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaucca ggacacccag      180

gauauauaaa uuucucauac gaaguauuaa caccacuaaa augguaucaa aauaugauaa      240

gacauccaua uacaucauac ggauacgaac caaugggagg augguaagga cuagugcauc      300

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      360

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      420

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      480

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aagaauu                                                     557


<210>  4940
<211>  590
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt13)

<400>  4940
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa aacaugauaa      240

gacacccauc acuacuacca gaccuaccac uagaagcaug gccagcaaca gacaaaacaa      300

aaagagaaga aguagacuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      360

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      420

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      480

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 590


<210>  4941
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt13)

<400>  4941
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuauua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua uauaaacuuc ucauacauaa      180

gacacccaua cacaucauac ggauacgaac caaugggagg auggcuacac caccaaauaa      240

uuccaguagu aucacaacaa acaccacaau cacacgcacu acaaccacac caccacauac      300

caaugguacc agcacaacaa ccaggaauac cacaacaacc aaugaugcca cuacccggac      360

aacacucaau gacacccaca caacaccacc aaccaaaccu accacuacca gcacaacaac      420

cauuccaacc acaaccagua caaccacaac cacaccaacc auuacaacca caaucaccaa      480

ugcacccaau acaaccacua cuaccacaac caccacuacc acccauguuc ucaaugcaau      540

cacuacuacc agaccuacca cuagaagcau ggccagcaac agacaaaaca aaaagagaag      600

aaguagacua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  4942
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt13)

<400>  4942
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uauucuucgc augccuauua ggagcauccc      120

uagcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacucacacc auuaaaaugg uaccaaaaca ugauaagaca cccauacaca ucauacggau      240

acgaaccaau gggaggcugg cuacaccacc aaauaauacc aguaguauca caacaaacac      300

cacaaucaca cgcacuacaa ccacaucacc acauaccaau gguaccagcc caacaaccag      360

gaauaccaca acaaccaaug augccacuac caggacaaca cucaaugaca ccaacacaac      420

accaccaacc aaaccuacca cuaccagcac aacaaccauu ccaaccacaa ccaguacaac      480

cacaacccca ccaaccacua caaccacaau caccaaugca cccaauccaa ccacuacuac      540

cacaaccacc acuaccacca auguucucaa ugcaaucccu acuacccgac cuaccacuag      600

aagccuggcc agcaacagac aaaacaaaaa gagaagaagu agacuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  4943
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt13)

<400>  4943
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaucaaaaca ugauaagaca cccaucacua uuaccagacc      240

uaccacuaga agcauggcca gcaacagaca aaacaaaaag agaagaagua gauuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  4944
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt13)

<400>  4944
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuauua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

accuauacuu agaagcaaua agaauagaca gaacagcauu cguacuaaca ccacuaaaau      240

gguaccaaaa caugauaaga cacccauaca caucauacgg cuacgaacca augggaggau      300

ggcuacacca ccaaauaaua ccagucguau cccaacaaac accccaauca cacgcauuac      360

aaccacacca ccacauacca auggucccag cacaacaacc agguauaccc caacaaccaa      420

ugaugccacu accaggacaa cacucaauga caccaacaca acaccaccaa ccaaaccuac      480

cacuaccagc acaacaacca uuccaaccac aaccaguaca accacaacca caccaaccac      540

uacaaccaca aucaccaaug cacccaauac aaccacuacu accacaacca ccauuaccac      600

ccauguucuc aaugcaauca cuauuacccg accuuccacu agaagcaugg ccagcaacag      660

acaaaacaaa aagagaagaa guagacuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  4945
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt13)

<400>  4945
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacucuucgc augccuacua ggcgcagcau      120

ucuccaugcc acuaccacca cacccaggac accccggaua cauaaacuuc ucauacgaag      180

uacucacacc acuaaaaugg uaccaaaaca ugauaagaca cccaacacca caaucacacg      240

cacuacaacc acaccaccac auaccaaugg uaccugcaca acaaccagga auaccacaac      300

aaccaaugau gccacuacca ggccaacacu ccaugacacc cacacaacac caccaaccaa      360

accuaccacu accagcccaa caaccauucc aaccacaacc cguacaacca caaccacacc      420

aaccauuaca accccaauca ccaaugcacc caauacaacc acuacuccca caaccaccac      480

uaccaccaau guucucaaug caaucacuac uaccagaccu accacuagaa gcauggccag      540

caacagacaa aacaaaaaga gaagaaguag acuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  4946
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt13)

<400>  4946
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa caugauaaga caccccuaca      180

caucauacgg auacgaacca augggaggau ggcuacacca ccaaauaaua ccaguaguau      240

cacaacaaac accacaauca cacgcacuac aaccacacca ccacauacca augguaccag      300

cccaacaacc aggcauacca caacaaccaa ugaugccacu accaggacaa cacucaauga      360

caccaacaca acaccaccaa ccaaaccuac cacuaccagc acaacaacca uuccaaccac      420

aaccaguaca accacaacca caccaaccac uccaaccaca aucacccaug caccccauac      480

aaccauuacu accacaacca ccacucccac caauguucuc caugcaauca cuacuaccag      540

accuaccacu agaagcaugg ccagcaacag acaaaacaaa aagagaagaa guagacuaag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  4947
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt13)

<400>  4947
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagguguag cacgucuacc auuauugcua gguuuauugc      120

uacuaccccg accgggacga ccacuagacu uagccgauua cacauaugac cuagcagaag      180

aggacgauag ugaaccauua aacuacaaag auccauguaa agcugccgca uucuuaggug      240

auauagcuuu agacgaagaa gauuuacgug cauuucaagu ccagcaagca guagauuuac      300

guagacauac ugcacgcaaa aguucaauaa aagcagcugu accaggaaac acaucaacac      360

cuuccuguca aucaacaaau ggucaaccuc aaagaggggc uugcggacgu uggaggggga      420

gaaguagaag uagacgugca gcaacaaguc gaccagaacg aguauggcca gauggaguaa      480

uuccauuugu aauuggugga aacuuuacug gaucacaaag agcuguauuc aggcaagcua      540

ugagacauug ggaaaaacau acuugcguua cauucuuaga acgaacagau gaagauuccu      600

auauaguauu uacuuauaga ccuugugggu gcuguaguua uguggguaga agagggggug      660

gaccacaagc aauaucaauu gguaaaaauu gugacaaauu uggaauaguu guacaugaac      720

uaggacaugu aguaggauuu uggcacgaac auacaagacc agauagagac agacauguau      780

ccauaguuag agaaaauaua caaccaggac aagaauauaa uuuccuaaaa auggagccac      840

aggaaguaga gaguuuggga gaaacuuacg acuucgacag uauaaugcau uaugcaagaa      900

auacuuuuuc acgaggaaua uuccuagaua cuauugugcc uaaauacgaa gugaauggug      960

uaaaaccucc aauuggucaa aggacuaggu uaagcaaagg agauauagca caagcgcgca     1020

aacuuuauaa auguccagca uguggugaaa cauuacagga cucaacagga aauuuuucau     1080

caccugaaua cccuaacggg uauagugcac auaugcacug uguauggaga auaucaguaa     1140

caccaggaga gaaaauaaua uuaaacuuca cuagccugga ucuuuauaga ucgagacucu     1200

guugguauga uuauguagaa guuagagaug gcuucuggag aaaagcacca uugagagggc     1260

guuuuugugg caguaaacua ccagaaccaa uaguaucuac agauuccaga uuaugggucg     1320

aguucagaag uucauccaau uggguaggaa aagguuucuu cgccguauau gaagcgauau     1380

gcggagggga uguaaagaaa gacuaugguc auauacaaag cccuaauuau ccugaugacu     1440

auaggccaag uaaaguuugu auuuggagaa uacaaguguc agaagguuuu cacguuggac     1500

ucacauuuca aucuuuugaa auagagcgcc augacucaug ugcguaugac uauuuagagg     1560

uaagagacgg acauucagaa ucuucuacuc uuauaggaag auauugugga uaugagaaac     1620

cagaugauau aaaaaguaca aguucucgac uaugguuaaa auuuguaagc gauggaagca     1680

uaaauaaagc aggauuugca guaaauuucu uuaaagaagu ugaugaaugc ucgagaccua     1740

auagaggggg augcgaacaa cgaugucuaa auacacucgg aagcuacaaa uguagcugug     1800

auccaggaua ugaacuugca ccggacaaaa gaagauguga agcugcaugc ggcggauuuc     1860

uaaccaaacu caauggauca auuacuuccc caggauggcc uaaagaauau ccaccgaaua     1920

aaaacugcau auggcaauua guagcuccaa cacaauaucg caucagcuua caauuugacu     1980

ucuuugaaac ugagggaaau gauguuugua aauaugacuu ugucgaaguc agaucaggcc     2040

ucacagcaga uucuaaauua cacggcaaau uuuguggaag cgaaaaaccg gaaguaauaa     2100

caucacaaua caauaacaug agaguagagu uuaaaagcga uaauacagua aguaagaaag     2160

gauuuaaagc acacuucuuc ucagauaaag acgaauguuc aaaagacaau gggggauguc     2220

aacaagacug uguaaauacg uuuggaucau augaauguca augccgaagu ggauucguac     2280

uucaugauaa uaaacaugau uguaaagaag cagguugcga ucacaaaguu acaucaacuu     2340

caggcacaau aacuucaccu aacuggccag auaaauaucc aucaaagaaa gaauguacau     2400

gggcaauauc uucaacccca ggucaucgcg uaaaauuaac auuuauggaa auggauauug     2460

aaucacaacc agaaugugca uaugaucacu uagaaguauu cgacggaagg gaugcaaaag     2520

caccaguauu agguagauuu uguggcagua agaaaccaga accaguucuu gcgacaggaa     2580

gccguauguu uuuaagauuu uacucagaua auuccguaca aagaaaagga uuucaagccu     2640

cccaugcgac ggaaugugga ggacaaguac gagcagaugu uaaaaccaaa gaccuauacu     2700

cacacgcaca auuuggugau aauaauuacc cagguggggu agacugcgaa uggguaauag     2760

uagcagaaga aggguacgga guugaauuag uauuccaaac auuugaagua gaagaagaaa     2820

ccgauugugg cuaugauuau auggaacuau ucgacggaua cgacuccaca gcaccgagau     2880

uaggacgaua cuguggaagu ggaccaccag aagaaguuua uucagcagga gacucagucu     2940

uagugaaauu ucauucggac gacacaauaa ccaagaaagg auuccacuua agauacacuu     3000

caacuaaauu ccaagauaca cuacacagua gaaaauaagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  4948
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt13)

<400>  4948
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgccggaa ccagaugccu auuagcccua cuauuaccac      120

aaguucuacu agguggagcu gcaggauuag uaccagaacu aggaagacga aaauucgcgg      180

cagcauccuc aggaagacca ucaucacagc caucagacga aguacuaucc gaauucgaac      240

uaagguuauu aucuauguuu ggauuaaaac aaagaccaac gccaucuaga gacgcagucg      300

uuccaccaua caugcuagau cuauauagaa gacacuccgg acaaccagga uccccagcac      360

ccgaucauag auuagaacga gccgcaucac gugcaaacac cguaagaucc uuccaccacg      420

aagaaucucu agaagaacua ccagaaacau caggaaaaac uacaagaaga uucuucuuua      480

accuaucauc uaucccaaca gaagaauuca ucacaucagc agaauuacaa gucuuuagag      540

aacaaaugca agacgcauua ggaaauaacu caucauuuca ccacagaauu aacauauacg      600

aaauaaucaa accagcaacc gcaaacagca aauucccagu cacucgauua cuagauacaa      660

gacuaguuaa ccaaaacgca ucaagauggg aaucauuuga cguaacuccc gcaguuauga      720

gauggacagc acaaggacac gcaaaucacg gauuugucgu ugaaguagcc cauuuagaag      780

aaaaacaagg aguuucaaaa agacacgucc gcauaagcag aucacuacau caagacgaac      840

auucuuggag ucaaauaaga ccacuacuug uaacauucgg ccacgacgga aaaggacacc      900

cauuacacaa aagagaaaaa agacaagcaa aacacaaaca aagaaaaaga cuaaaaucau      960

caugcaaaag acauccauua uacguagauu ucucagaugu aggauggaac gacuggauag     1020

uagcaccacc aggauaccac gcauuuuacu gccauggaga augcccauuu ccacuagcag     1080

accaccucaa cucaaccaac cacgcaauag uucaaacccu aguaaauuca guaaauucaa     1140

aaauaccaaa agcaugcugu gucccaacag aacuuucugc aauaucaaug cuauauuuag     1200

augaaaacga aaaaguaguu cuaaaaaauu accaagacau ggucguagaa ggaugcggau     1260

guagauaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  4949
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt13)

<400>  4949
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaccaggaa auagaaugcu caugguagua uuauuaugcc      120

aaguacuucu agguggagcu ucacaugcau cacuuauacc agaaaccgga aaaaaaaaag      180

uagcagaaau acaaggacau gccggaggaa gaagauccgg acaaucacau gaauuacuac      240

gagauuuuga ggccacuuua uuacagaugu ucggauuaag aagacgaccu caaccaucaa      300

aaucagcagu aauuccagac uacaugcgag aucuauacag auuacaauca ggagaagaag      360

aagaagaaca aauacacagu accggacuag aauacccaga aagaccagca ucaagagcca      420

auaccguuag aucauuccac caugaagaac auuuagaaaa uauaccagga acaucagaaa      480

auucagcuuu cagauuuuua uucaauuuaa gcagcauacc agaaaacgaa gucauaucau      540

cagcagaacu aagacuauuu agagaacaag uugaccaagg accugacugg gaacgcggau      600

uccacagaau aaauauauac gaaguaauga aaccaccugc ugaaguagua ccaggacacc      660

uaauaacuag auuacuagau acaagacuag uacaccauaa uguaacaagg ugggaaacau      720

uugacguauc accggcagua uuacggugga caagagaaaa acaaccaaau uacggacuag      780

caauagaagu cacacacuua caucaaacaa gaacacauca gggucaacac guaagaauau      840

cacgaucacu uccacaaggu ucagguaacu gggcccaauu aagaccauua cuaguaacau      900

uuggacauga cggaagagga cacgccuuaa cacgaaggcg aagagccaaa agaaguccaa      960

aacaccauuc acaaagagca cgaaaaaaaa acaaaaauug ccgaagacau ucacuauacg     1020

uagacuuuuc agaugucgga uggaaugacu ggaucguagc accaccaggc uaccaagcau     1080

uuuacuguca cggagauugc ccauuuccac uagcagauca cuuaaacuca accaaucacg     1140

caauaguaca aacacuagua aauucuguaa acagcucuau accaaaagcu uguuguguac     1200

caacagaacu aucagccaua ucuauguuau aucuagauga auaugauaaa guaguauuaa     1260

aaaacuauca agaaaugguc guagaaggau gcggauguag auaaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  4950
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt13)

<400>  4950
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggauuag gaagacgagc acaauggcua ugcugguggu      120

gggguuuauu auguagcugu ugcgguccac caccuuuaag accaccauua ccagccgcag      180

cugcugcugc agcaggcggu caacuauuag gagauggggg aucacccggg agaacagaac      240

aacccccacc aucaccccaa agcucaucag gguucuuaua cagaagauua aaaacacaag      300

aaaaacgcga aaugcaaaaa gaaauacuaa guguauuagg auugccacau agaccuagac      360

cauuacaugg auuacaacaa ccacaaccuc cagcuuuaag acaacaagaa gaacaacaac      420

aacaacaaca auuacccaga ggagaaccac ccccaggaag acuaaaaucu gcuccauuau      480

ucaugcuaga ccuauacaau gcacuaagcg cagacaauga cgaagaugga gcuucugaag      540

gagaaagaca acaaucaugg ccucaugaag cagcuucaag cagucaaagg agacaaccac      600

caccaggagc agcacaccca cuuaaucgaa aaagccuacu agcacccggc ucuggaucag      660

gaggcgcaag uccauuaaca ucagcacaag auagcgcguu uuuaaaugac gcagacaugg      720

uaaugucauu cgugaauuua guagaauacg auaaagaauu uucuccaaga caaagacacc      780

acaaagaguu caaauucaau cuaucccaaa uaccugaagg agaaguagua acugcagcag      840

aauuuagaau cuacaaagac uguguaaugg gaucauucaa aaaucaaacu uucuuaauau      900

cuaucuacca aguauuacaa gaacaucaac auagagacuc ugauuuauuc cucuuagaca      960

caagaguugu augggcauca gaagaagguu ggcuagaauu ugacauuacu gcaacaucaa     1020

acuuaugggu aguaacacca caacauaaca ugggacuaca auuaucaguc guaaccagag     1080

augguguuca uguacacccu agagcugcag gacuuguagg cagagacgga ccauacgaua     1140

aacaaccauu caugguagca uucuucaaag uaucagaagu acauguaaga acaacacgau     1200

cugcuagcuc aagaagaaga caacaaaguc gcaacagauc uacacaauca caagauguag     1260

cacgaguauc aucugcuuca gacuauaacu ccuccgaacu aaaaacagca ugcaggaaac     1320

acgaauuaua cguuuccuuc caagauuuag gauggcaaga cuggauaaua gcacccaaag     1380

gauacgcugc aaacuacugc gacggugaau guucauuucc auuaaaugca cauaugaacg     1440

caacaaacca ugcaaucgua caaacucuag uacaccuaau gaauccagaa uaugucccca     1500

aaccauguug cgcacccaca aaacuuaacg caauaucagu cuuauacuuu gacgacaauu     1560

caaauguaau ccuaaagaaa uauagaaaca ugguagucag agccugcggu ugccauuaag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  4951
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt13)

<400>  4951
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauguaagau cacuaagagc agcugcccca cacucauuug      120

uagcacugug ggcaccacuu uuuuuacuaa gaagcgcauu agcagacuuu ucacuagaca      180

augaaguaca uucaagcuuu auucauagga gacuucgguc acaagaaaga cgugaaaugc      240

aaagagaaau auuaucuauu cuaggacuac cacaccgccc aagaccacau cuacaaggaa      300

aacacaauuc agcuccaaug uucaugcuag aucuuuauaa cgcaauggca gucgaagaag      360

gaggaggccc cggaggacaa ggauuuuccu auccauauaa agcaguauuu ucaacacaag      420

gaccuccucu agcaagucua caagauucac auuucuuaac agaugcagau augguaaugu      480

cauuuguaaa uuuaguagaa caugauaaag aauuuuuuca cccacguuac caccauagag      540

aauucagauu cgaucuaucu aaaauaccag aaggugaagc aguaacagca gcugaauuca      600

gaauauacaa agauuacaua cgagaaagau uugacaacga aacauucaga auaucaguau      660

aucaaguacu acaagaacac uuagguagag aaagcgaucu auuucuauua gacuccagaa      720

cacucugggc aucagaagaa ggcuggcuag uauucgauau aacagcaacc aguaaucacu      780

gggucguaaa cccaagacac aaccucggac uacaauuauc aguagaaaca uuagacggcc      840

aaaguauuaa cccaaaacuc gcaggacuaa uaggaagaca cggaccacaa aacaaacaac      900

cauucauggu agcauucuuu aaagcaaccg aaguacacuu cagaucaaua cgaucaacag      960

gauccaaaca aagaagccaa aauagaucaa aaacuccaaa aaaucaagaa gcauuaagaa     1020

uggcaaaugu agcugaaaau ucaucaagug aucaaagaca agccugcaaa aaacacgaau     1080

uauacguauc cuuccgagau uuaggauggc aagacuggau aauagcaccu gaaggcuacg     1140

ccgcauacua cugugaagga gaaugugcau uucccuuaaa cucauauaug aacgcaacua     1200

aucacgcuau aguacaaaca cuaguacacu uuauaaaucc cgaaacagua cccaaaccau     1260

gcugcgcacc aacacaacuc aacgcuauau caguauuaua uuuugacgac ucuucuaacg     1320

uuauccuaaa aaaauaucga aauaugguag ucagagcaug uggcugccac ugaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  4952
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt13)

<400>  4952
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagcaucag cagcacuacu augccuacua cuaacagcag      120

cagcauucuc accacaagga cuagcacaac caguaggaau aaacacauca acaacaugcu      180

gcuacagauu cauaaacaaa aaaauaccaa aacaaagacu agaaucauac agaagaacaa      240

caucaucaca cugcccaaga gaagcaguaa uauucaaaac aaaacuagac aaagaaauau      300

gcgcagaccc aacacaaaaa uggguacaag acuucaugaa acaccuagac aaaaaaacac      360

aaacaccaaa acuauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  4953
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt13)

<400>  4953
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uugcuuacuu uaauaauauu acuuccaguu gucaguaaau      120

uuucguuugu gucauuaucu gcaccacaac auuggaguug uccagaaggu acgcuagcag      180

gcaacgguaa uucuacgugu gucgguccag cgccauuucu aaucuuuucu caugguaacu      240

ccauuuuuag aauagauaca gaagguacaa auuacgaaca auuaguaguu gacgcaggag      300

ucagcguaau aauggacuuu cauuauaaug agaaaagaau cuauugggua gacuuggaaa      360

gacaauuacu ucagcgugua uucuugaaug gauccagaca agaaagagua uguaauauag      420

agaaaaaugu aucagguaug gcuauaaacu ggauaaauga agaagugauu uggucaaauc      480

aacaagaagg gaucauuacc guuacagaca ugaaaggaaa uaauucccac auacuacuau      540

cagcacuaaa auaucccgcc aauguugcag uagauccagu ggaaagauuu auauuuuggu      600

ccucagaagu agcaggauca uuauauagag cagacuuaga cggugugggu guuaaggcuu      660

uacuagaaac uucugagaaa auuaccgcag uaaguuuaga cguuuuagac aaaagauuau      720

uuuggauuca auauaauagg gaagguucaa auucacuuau auguucuugc gacuaugaug      780

guggaucagu gcauauaagu aaacauccaa cgcaacacaa ucucuuugca augucuuuau      840

uuggugauag aauauuuuac agcacuugga aaaugaaaac aauauggaua gccaacaaac      900

auaccggaaa agauauggua aggauaaauc uacacaguuc cuucguuccu uuaggugaac      960

uaaaaguagu acauccacua gcgcaaccua aagcggaaga ugacacuugg gaaccagaac     1020

aaaaacuaug uaaguuacga aaaggcaacu guucaucuac agugugcggg caagacuuac     1080

aaagucacuu auguaugugc gcggaaggcu augcgcucag uagagauaga aaauauugug     1140

aagauguaaa ugaaugugca uuuuggaacc auggauguac acuaggaugc aaaaauacac     1200

cagguucaua uuauuguacu ugucccguug gauuuguccu guuaccagac ggcaaaaggu     1260

gccaucagcu aguaaguugu ccacguaaug uuucagaaug uagccacgau uguguuuuga     1320

caagugaagg accacuaugc uuuugcccag aaggaucagu auuagaaagg gauggaaaaa     1380

cauguagugg uuguaguuca ccagauaaug gagguuguag ucaacuuugu guuccauuau     1440

cuccuguauc uugggaaugc gauuguuucc cagguuauga uuuacaauua gaugagaaaa     1500

guugugcagc gucuggccca caaccauucu uacucuuugc aaauucacaa gauauaagac     1560

acaugcauuu cgauggcacc gacuacggca cccuauuaag ucaacaaaug gggaugguau     1620

augcacuuga ccaugaucca guagaaaaca aaauauacuu cgcacauacc gcacucaaau     1680

ggaucgaaag agcaaauaug gacggaaguc aaagggaacg guugauugaa gaaggaguag     1740

auguaccuga ggguuuagca guugauugga uagggaggag auuuuauugg acggacaggg     1800

ggaaaaguuu aauaggacga agcgaccuca acgggaaaag aagcaaaaua aucacuaaag     1860

aaaauauuuc acaaccaaga ggaauugcug uacauccaau ggcaaaacgu cuauuuugga     1920

cagacacagg aauaaauccu agaauagagu ccaguucacu gcaaggauug gggagauuag     1980

ugaucgccag uuccgaccua auauggccau cgggaauuac aauagacuuu uuaaccgaua     2040

aacuauauug gugcgaugca aaacagucag uaauugaaau ggccaaucua gauggaucua     2100

aaagaagaag acuaacacaa aaugaugugg gacacccauu ugcuguugcc guuuucgagg     2160

acuacgucug guuuucagau ugggcaaugc caagugucau gagagucaau aagagaacug     2220

guaaggauag agucagauua caaggcucaa uguuaaaacc aucgagucua gucguagucc     2280

acccauuagc aaaaccaggu gcagaucccu gcuuauauca aaauggaggg ugcgaacaca     2340

uauguaagaa aagacuuggc acagcauggu guucauguag agaaggauuu augaaggcuu     2400

cagauggaaa aaccuguuua gcauuagaug gccaucaacu ucucgccgga ggagaaguug     2460

acuugaaaaa ccaaguaaca ccccuagaua uauuaagcaa aacaagaguu agcgaagaua     2520

acauaacaga aucucaacau auguuaguag cagaaauuau ggucucagau caagaugacu     2580

gcgcaccugu aggauguucu auguaugcua gaugcauauc agagggggaa gaugcgacau     2640

gucaaugcuu aaaaggauuu gcaggcgacg gaaaauuaug cucagacaua gacgaaugug     2700

aaaugggagu uccuguuugu ccuccagcau cuuccaaaug uauaaauacc gaaggugguu     2760

auguauguag auguagugaa ggauaccaag gggacgguau ccauuguuua gauauagaug     2820

aaugccaauu gggagaacac uccuguggag agaacgcauc cuguacaaau acugaaggag     2880

guuauacgug uaugugcgca ggaaggcuuu ccgaaccugg uuuaauuugc ccagauucaa     2940

caccuccccc acaccuucgu gaagaugacc accauuauag uguacgaaau ucagauucug     3000

agugcccacu aagccaugau ggauauuguu uacacgaugg aguaugcaug uacauagaag     3060

cguuggauaa auacgcuugu aauugugugg uuggauacau aggugaaaga ugucaauacc     3120

gagaccuaaa auggugggaa cuaagacaug ccgggcacgg acaacaacaa aaaguaauag     3180

ucguugcagu guguguagua gucuuaguca ugcuauuacu auugagccuc uggggugcac     3240

acuauuauag gacacaaaaa cuacuaucua aaaaccccaa aaauccauau gaagaaucaa     3300

gucgugaugu cagaucaaga agaccagcag acacagaaga cggaauguca ucguguccac     3360

aaccaugguu ugugguaauu aaagaacauc aagaucucaa aaacggaggc caacccguug     3420

cuggugaaga uggacaagca gcagauggua guaugcagcc cacaucaugg cgacaagagc     3480

cacaauuaug cggcauggga acagaacaag guuguuggau uccaguuagu ucugacaaag     3540

gaagcugucc gcaagugaug gagaggucau uucauaugcc aagcuacgga acacagacac     3600

ucgaaggcgg aguagagaaa ccacauucgc uucuuucugc aaacccauua uggcaacaaa     3660

gagcucuaga uccaccucac caaauggaau ugacucaaua aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  4954
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt13)

<400>  4954
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagcaggca gaagaaugga aaugcuaugu gcaggacgag      120

uaccagcauu auuacuaugu cuaggauucc auuuauuaca agcaguacua agcacaacag      180

uaauaccaag cuguauacca ggagaaagcu cagacaauug cacagccuua guacaaacag      240

aagacaaucc aagaguagca caaguaagua uaacaaaaug cucaagcgau augaauggau      300

auugcuuaca cggacaaugu auauaucuag uagacaugag ccaaaacuau ugcagaugcg      360

aagucggaua cacaggagua agaugugaac auuucuucuu aacaguacau caaccacuau      420

caaaagaaua cguagcauua acaguaauau uaauaauacu auuucuaaua acaguaguag      480

gaagcacaua cuauuucugu agaugguaca gaaacagaaa aucgaaagaa ccaaaaaaag      540

aauacgaacg aguaacauca ggagauccag aacuaccaca aguauaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  4955
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt13)

<400>  4955
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagaaggag aaauaacaac auucacagca cuaacagaaa      120

aauucaaccu accaccagga aacuacaaaa aaccaaaacu acuauacugc ucaaacggag      180

gacacuuccu aagaauacua ccagacggca caguagacgg aacaagagac agauccgacc      240

aacacauaca acuacaacua ucagcagaau caguaggaga aguauacaua aaaucaacag      300

aaacaggaca auaccuagca auggacacag acggacuacu auacggauca caaacaccaa      360

acgaagaaug ccuauuccua gaaagacuag aagaaaacca cuacaacaca uacauaucaa      420

aaaaacacgc agaaaaaaac ugguucguag gacuaaaaaa aaacggaagc ugcaaaagag      480

gaccaagaac acacuacgga caaaaagcca uacuauuccu accacuacca guaucaucag      540

acuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  4956
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt13)

<400>  4956
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaggaguag gagggggaga uguagaagau guaacaccaa      120

gaccaggugg augucaaauu agcggaagag gugcaagagg auguaaugga auaccaggag      180

cagcagcuug ggaagcagca uuaccgagaa gacgaccgag aagacauccg agugugaauc      240

caagaucaag agcagcugga agcccaagaa caagaggaag aagaacagaa gaaagaccaa      300

guggaagcag auuaggagau agaggaagag gacgagcauu accaggagga agauuaggag      360

gaagaggaag aggaagagca ccagagagag uaggagggag aggaagagga agaggaacag      420

cagcgccaag agcagcacca gcagcaagag gaucaagacc aggaccagca ggaacaaugg      480

cagcgggaag uauaacaaca uuaccagcuc uaccagaaga uggaggaagu ggggcguuuc      540

caccaggaca uuuuaaagau ccaaaaagau uauauuguaa aaauggagga uuuuuuuuaa      600

gaauacaucc agauggaaga guagaugggg uaagagaaaa aucagaucca cauauaaaau      660

uacaauuaca agcggaagaa agaggagugg uaaguauuaa aggaguuugu gcaaauagau      720

auuuggcgau gaaagaagau gggagguuau uagcaaguaa auguguaacg gaugaauguu      780

uuuuuuuuga aagacuagaa agcaauaacu auaacacaua uagaucgaga aaauacacau      840

caugguaugu agcauuaaaa agaacaggac aauauaaacu aggaaguaaa acaggaccag      900

gacaaaaagc aauauuauuu uuaccaauga gugcaaagag uuaaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  4957
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt13)

<400>  4957
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uacuaacaug gauacuacca acacuacuau      120

acagaagcug cuuccacaua auaugccuag uaggaacaau aucacuagca ugcaacgaca      180

ugacaccaga acaaauggca acaaacguaa acugcucauc uccagaaaga cacacaagau      240

cauacgacua cauggaagga ggagacauaa gaguaagaag acuauucugc agaacacaau      300

gguaccuaag aauagacaaa agaggaaaag uaaaaggaac acaagaaaug aaaaacaacu      360

acaacauaau ggaaauaaga acaguagcag uaggaauagu agcaaucaaa ggaguagaau      420

cagaauucua ccuagcaaug aacaaagaag gcaaacuaua cgcaaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa cuaauacuag aaaaccacua caacacauau gcaagcgcaa      540

aauggacaca caacggagga gaaauguucg uagcauuaaa ccaaaaagga auaccaguaa      600

gaggaaaaaa aacaaaaaaa gaacaaaaaa cagcacacuu ccuaccaaug gcaauaacau      660

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  4958
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt13)

<400>  4958
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauuauuac caucaguagu acuaaaacua uuucuagcag      120

caguacuauc agcauuagua acaggagaaa gccuagaaag acuaagaaga ggacuagcag      180

caggaaccuc aaacccagac ccaccaacag uaucaacaga ucaauuacua ccacuaggcg      240

gaggaagaga uagaaaagua agagacuuac aagaagcaga ccuagauuua cuaagaguaa      300

cauuaucauc aaaaccacaa gcacuagcaa caccaaacaa agaagaacac ggaaaaagaa      360

aaaaaaaagg aaaaggauua ggaaaaaaac gagauccaug ccuaagaaaa uauaaagacu      420

ucugcauaca uggagaaugc aaauacguca aagaacucag agcaccaagc ugcauauguc      480

acccuggaua ccacggagaa agaugccacg gacuaagucu uccaguagaa aacagauuau      540

acacauacga ccacacaaca auacuagcag uaguagcagu aguauuaagc ucaguauguc      600

uauuaguaau aguaggucua cuaauguuca gauaucaccg aagaggagga uacgauguag      660

aaaaugaaga aaaaguaaaa cuaggaauga caaauagcca cuaaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  4959
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt13)

<400>  4959
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uggguaacua aacuauuacc agcauuacua uuacaacaug      120

uccuacuaca ccuacuauua cuaccuauug caauaccaua cgccgaaggu caaagaaaac      180

gaagaaauac aauacaugag uucaaaaagu cagcaaaaac aacauuaauc aaaauagacc      240

cagcacuaaa aauaaaaaca aagaaaguaa auacagcaga ucaaugugca aacagaugca      300

cuagaaacaa aggacuacca uuuacaugua aagcauucgu auuugauaaa gcaagaaaac      360

aaugucuaug guuuccauuu aauagcauga guucaggagu aaagaaagag uucggacaug      420

aauuugaccu auaugaaaau aaagacuaua uaagaaauug cauaauaggu aaaggaagau      480

cauauaaagg aacaguuucc aucacaaaau caggaauaaa augucaaccc uggucaucaa      540

ugauaccaca cgaacauagc uuucuaccaa gcucauacag agguaaagau cuacaagaaa      600

auuauuguag aaauccgaga ggugaagaag gcggaccaug guguuuuacu ucuaauccag      660

aaguacgaua ugaaguaugu gauauaccgc aaugcucaga aguagaaugu augacaugua      720

acggagaauc auauagaggu uugauggauc auacagaauc aggcaaaaua ugucaaaggu      780

gggaccacca aacuccacau cgacauaaau uucuaccaga acguuaucca gauaaaggcu      840

uugaugauaa uuacugucga aacccagacg gacaaccaag accuuggugc uacacauuag      900

auccccauac ucgaugggaa uacugugcaa uaaaaacaug cgcagauaac acaaugaaug      960

acacagaugu uccucuagaa acuacugaau gcauacaagg acaaggagaa ggauaccgag     1020

gaacuguaaa uacaauaugg aauggaauac cuugucaaag augggauuca caauauccuc     1080

augaacauga caugacccca gaaaauuuua aaugcaaaga ucuaagagaa aauuauugca     1140

gaaacccaga cggaucugaa ucgccauggu guuuuacaac ugauccuaac auaagaguag     1200

gcuauugcuc ucagauaccg aauugcgaca ugagccaugg acaagacugu uauagaggaa     1260

auggcaaaaa uuacauggga aaucucaguc aaacaagauc aggauuaacu uguucaaugu     1320

gggacaaaaa uauggaagau uuacauagac acauauucug ggaaccagac gcaucaaaau     1380

uaaaugaaaa cuauugcaga aauccagaug acgacgcaca cgggccaugg uguuauacag     1440

gaaauccauu aauaccaugg gacuacuguc cuauaagccg augugaagga gauacaacuc     1500

ccacaauugu aaacuuagau cauccaguaa ucucaugugc caaaacaaaa caauuaagag     1560

ucguaaacgg uauaccuacu aggacaaaca uaggcuggau ggugucacuu agauauagaa     1620

auaaacacau augcggaggc agucuuauaa aagaaucaug gguccucaca gcaagacaau     1680

guuuucccag cagagauuua aaggacuaug aagcaugguu aggaauacac gauguacacg     1740

gacgaggaga cgaaaaaugu aaacaaguac uaaauguuuc ucagcuaguc uauggaccag     1800

aagggagcga uuuagucuua augaaacuag caagaccggc agucuuagac gacuucguau     1860

cuacaauuga uuuaccuaac uacggaugca cgauaccaga aaagacuagc uguucuguuu     1920

auggaugggg uuauacugga cuaaucaacu acgacggacu auuaagggug gcacauuuau     1980

auauuauggg aaacgaaaaa uguucucaac accacagagg aaaaguaaca uuaaacgaau     2040

cagaaauaug cgcaggagca gagaaaaucg gaucaggccc gugugaagga gacuauggug     2100

ggccgcuagu gugcgaacaa cacaaaaugc gaaugguauu agggguaaua guaccuggac     2160

ggggaugcgc cauaccaaau agaccaggaa uauucguaag aguagcauau uaugccaaau     2220

ggauacauaa aauaauacua acauauaaag uaccacaauc uuaaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  4960
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt13)

<400>  4960
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaagcag cugcaauagg aauagaucua ggaacaacau      120

acuccugugu aggaguauuc caacacggaa aaguagaaau aaucgcaaau gaucaaggua      180

acagaacaac accaucauac guugcauuua cagacacaga aagauuaaua ggagaugcag      240

ccaaaaacca agucgcacua aauccacaaa acacaguauu ugaugcaaaa cgcuuaauag      300

gaagaaaauu uggcgaucca guaguacaau cagacaugaa acauuggcca uuucagguaa      360

uaaacgaugg agauaaacca aaaguucaag uuaguuacaa aggcgaaacu aaagcauuuu      420

acccggaaga gauaucaagc augguauuaa caaaaaugaa agaaaucgca gaggcuuauu      480

uaggauaccc aguaacaaac gcaguaauaa caguaccagc uuacuuuaau gauagucaga      540

gacaagcaac uaaagaugcc ggaguaauug ccggacuaaa cguacuaaga auaauaaacg      600

aaccaacugc agcagcaaua gcauauggau uagauagaac aggcaaagga gaaagaaaug      660

uauuaauauu cgaccuagga ggagguacau ucgacguguc aauauuaaca auugaugaug      720

gaauauucga aguaaaagca acagccgggg acacacauuu agggggagaa gauuuugaca      780

acagacuggu aaaccauuuu guagaagaau uuaaaagaaa acacaagaaa gacauuucac      840

aaaauaaaag ggcaguuaga agacuaagaa cugcauguga gagggcaaaa aggacguuaa      900

gcaguaguac ccaagcauca cuagagauag acucauuauu ugaaggaauu gauuuuuaua      960

cuucaaucac gagagcgaga uuugaagaau uauguaguga ucucuuuaga ucgacauuag     1020

aaccugucga aaaagcacua agagaugcga aacuagacaa agcacaaaua caugacuuag     1080

uucuaguagg aggaucaacc agaauaccaa aaguacaaaa acuacuacaa gauuucuuca     1140

acggaaggga cuuaaauaaa ucaauaaacc cagaugaagc ugucgcuuac ggugcagcug     1200

uccaagcagc aauacuaaug ggagauaaaa gcgagaaugu gcaagacuua uuauuauuag     1260

acguugcacc ucuaucgcua ggacuagaaa cagcaggagg aguaaugaca gcacuuauaa     1320

aaagaaacag cacaauaccg acuaaacaaa cgcaaauauu uacaaccuau ucagauaacc     1380

aaccuggcgu ccuuauacag guuuaugaag gugaaagagc aaugacaaaa gauaacaauc     1440

uacuaggaag auuugagcua aguggaauac caccagcacc ucgaggagua ccacaaauag     1500

aaguuacauu cgacauagac gcuaauggca uucuaaaugu gacagcuacu gacaaaagua     1560

ccggaaaagc aaauaaaaua acuauuacaa acgauaaagg aagacuaagc aaggaagaga     1620

uagaacgcau gguacaggaa gcagaaaaau acaaagcgga agacgagguc cagcgagaaa     1680

gaguaagcgc uaaaaacgca uuagaaucau augcauucaa caugaaaagc gcaguagaag     1740

augaaggacu aaaagguaaa auaagcgaag cagauaaaaa gaaaguacua gauaaauguc     1800

aagaaguuau aaguugguua gaugcaaaua cuuuagcgga aaaagaugaa uuugaacaua     1860

aaagaaaaga acuagaacag guaugcaauc cuauuauauc aggauuauac caaggagcug     1920

gaggaccagg accaggaggc uucggagcac aaggaccgaa aggaggaucc ggaucagggc     1980

caacaauaga agaaguagau uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4961
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt13)

<400>  4961
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaaagcug cagcaauagg aauagaccua ggaacaacau      120

acuccugcgu aggaguauuu cagcauggua aaguugaaau aauagcuaac gaccaaggca      180

acagaacaac ccccucauac gucgcauuca cagauaccga aagauuaauc ggagaugcgg      240

cuaaaaacca aguggcacuc aauccacaaa acacaguauu ugacgcaaaa agacugauag      300

gaagaaaauu cggcgaucca gugguucaau cagauaugaa acauuggcca uuccagguaa      360

uaaaugaugg agauaaacca aaaguacaag uaucauauaa aggagaaaca aaagcauuuu      420

auccagagga aauaaguagu augguauuaa caaaaaugaa agaaauagcu gaagcauauc      480

ucggauaccc aguaacaaac gccguaauaa caguuccagc auauuucaac gacagucaaa      540

gacaagcaac aaaagaugca ggaguaauag cuggccuaaa uguacuuaga auaauaaaug      600

aaccuacugc ugcugccaua gcauacggac uagaucgaac aggcaaagga gaaagaaaug      660

uuuuaauauu cgaccuugga ggaggaacau ucgacguaag cauuuuaaca auagaugaug      720

gaauauuuga aguuaaagcc acugcagggg auacucaccu aggaggagaa gauuucgaua      780

acaggcuagu uaaucauuuu guagaagaau uuaaaagaaa acauaagaaa gacauaaguc      840

aaaacaaaag agcaguaaga agauugagaa cagcauguga aagagcuaaa agaacgcuaa      900

gcucaagcac acaagcaagu uuagaaauag auaguuuauu ugaaggaaua gauuuuuaua      960

cuucgauaac gagagcaaga uuugaagaau uauguucaga uuuauuuaga ucaacguuag     1020

aaccaguuga aaaagcacua agagacgcaa aauuagauaa agcucaaaua caugaccuag     1080

ucuuggucgg aggcucaaca cgaaucccua aaguacaaaa auuacuucaa gauuucuuua     1140

acgguagaga ucuaaauaaa ucaauaaauc ccgacgaagc uguagcauau ggagcagcug     1200

uacaagccgc aauucuuaug ggagauaaau cagaaaaugu acaagauuug cuacuuuuag     1260

acguggcacc acuuagccua ggacuagaaa cagcuggagg aguaaugacc gcauuaauaa     1320

aacgcaacuc gacuauacca acaaaacaaa cacaaaucuu uacaacauac agugauaauc     1380

aaccaggagu acuaauacaa guauaugaag gagaaagagc aaugacuaaa gacaauaauc     1440

uacuaggacg guucgaacua agcggcauuc caccagcacc ucgaggagua ccacaaauug     1500

aaguaacauu ugauauagac gcaaacggga uauuaaacgu uacagcaacc gauaaaagca     1560

caggcaaagc aaacaaaaua acaauuacaa augauaaagg aagacuuuca aaagaagaaa     1620

uagagagaau gguacaagaa gcugagaaau acaaagccga agacgaaguc caaagagaaa     1680

gaguuagcgc uaaaaacgca cuggaaucau augcuuucaa uaugaaauca gcaguagagg     1740

acgaaggacu aaaaggcaaa auuucagaag cagacaaaaa gaaaguacua gauaaauguc     1800

aagaaguaau uagcugguua gaugcaaaua cccuggcaga gaaagaugaa uuugaacaua     1860

aaagaaaaga auuagaacaa guaugcaauc ccauaauauc aggucuguau caaggagcag     1920

gcgggccagg accaggagga uuuggagcac agggaccaaa agguggaucc gguagcggcc     1980

caacaaucga agaaguagau uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4962
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt13)

<400>  4962
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaacagcaa aaggaauagc aauaggaaua gacuuaggga      120

caacuuacag uuguguugga guauuucagc acgggaaagu cgaaauaaua gcaaacgauc      180

aagguaauag gaccaccccu ucguacguag cauuuacaga uacugaaaga cuaauaggug      240

augcagcgaa aaaccaaguc gcaaugaacc cgcaaaauac aguauuugac gcaaaacggu      300

uaauuggaag aaaguuuaac gacccaguug uacaagcaga uaugaaauua uggccauucc      360

aaguaauaaa cgaaggagga aaaccuaaag uguugguauc cuauaaaggc gaaaacaaag      420

cauuuuaucc ggaagaaaua ucaucaaugg uacuaacaaa acuuaaagaa acggcagaag      480

cauuucuagg acauccaguc acaaacgcag uaauaacagu uccagcauac uuuaacgaua      540

gucaaagaca agcaacgaaa gaugcaggag uuauagcagg ucuaaaugua cuuaggauaa      600

ucaacgaacc aacggcagca gcaauagcau acggacuaga uaaaggagga caaggagaaa      660

gacauguacu aauauuugau uuaggcggag gaacauucga cguaaguaua uuaaccauag      720

augauggaau auucgaagua aaagcaacag caggggacac acacuuagga ggcgaagacu      780

ucgauaacag gcuaguaagc cauuuuguag aagaguucaa aagaaaacac aagaaagaua      840

uaucacaaaa uaaacgcgca guacgaagac ucagaacagc uugcgaaagg gcaaaaagaa      900

ccuuaagcuc uaguacacaa gcaaaccugg aaaucgauag uuuauacgaa ggaauagauu      960

ucuauacauc aaucacuaga gcuagauuug aagaacucug ugcagaucua uuuagaggaa     1020

cauuagaacc cguagaaaaa gcgcuuagag acgccaaaau ggacaaagca aaaauacaug     1080

acauaguccu aguaggugga aguacgcgua uaccaaaagu acaaagauua uuacaggauu     1140

auuucaacgg aagagaucuu aacaaaagua uaaaucccga ugaagcagua gcauacggug     1200

cagcaguaca ggcagcaaua cuaaugggag auaaaucuga aaaaguacaa gacuuacuac     1260

uguuagacgu agcaccacuu ucacuaggac uagaaacagc uggaggugua augacagcau     1320

uaauaaaaag aaauucaacu auaccaacua aacaaacaca aauauuuaca accuauagug     1380

acaaucaacc aggaguacua auacaaguau augaaggaga aagagcaaug acaaaagaua     1440

acaaucugcu aggaagauuu gaucuaacgg gaauaccacc agcaccaaga ggaguaccac     1500

aaauagaagu aacguuugac auugaugcaa auggaauacu aaacgugacc gccacagaua     1560

aaaguacugg aaaagucaau aaaauaacua ucacaaacga uaaagggaga cuaagcaaag     1620

aagagauaga aagaaugguu uuagaugcag aaaaauacaa agcagaagac gagguacaaa     1680

gagagaaaau agcagcuaaa aaugcauuag aaucauaugc auuuaauaug aaaagcguag     1740

uaucagacga aggauuaaaa ggaaaaauaa gcgaaaguga uaaaaacaaa auacuagaca     1800

aaugcaauga acuauuauca ugguuagaag uaaaucagcu agcagaaaaa gaugaauuug     1860

accauaaaag aaaggaacua gaacaaaugu guaauccaau aauaacaaaa uuauaccaag     1920

gggguugcac aggaccugca uguggaacag gauauguccc aggcagacca gcaacaggac     1980

caacgaucga agaaguggau uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  4963
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt13)

<400>  4963
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucagcacgug ggcccgcgau agguauagau cuagggacaa      120

cauacagcug cguuggggug uuucaacacg gaaaaguaga aauaauagca aaugaucaag      180

guaacagaac cacaccaagu uacguugcau uuacagauac ugaaagguua auaggagacg      240

cagcgaaaaa ccaaguagcc augaacccaa caaauacgau cuuugacgca aaacgucuua      300

uaggacguaa auuugaggac gcgaccgucc aaagcgauau gaaacacugg ccauuuagag      360

uaguaagcga aggaggaaaa cccaagguac aaguagaaua caaaggagaa acaaaaaccu      420

uuuucccuga agaaauauca ucaaugguau uaacaaaaau gaaagaaaua gcagaagccu      480

accuuggggg aaaaguccac ucagcaguaa uaacgguacc agcauacuuu aacgauagcc      540

agagacaagc cacaaaagau gcagggacaa uaacaggacu caauguauua agaauaauua      600

augagccuac agcagcagca auagcauaug gauuagauaa gaaaggaugu gcgggugggg      660

aaaagaacgu auuaauauuu gaccuaggug gaggaacauu cgacguaagu auacuaacaa      720

uagaagaugg aaucuucgaa gugaaaagua cagcaggaga uacucaccug ggcggagaag      780

auuuugauaa ucgaaugguu ucacauuuag cagaagaguu caaacgaaag cacaagaaag      840

auauaggacc aaacaaaaga gcaguacgaa gauugcgaac agcgugcgaa agagcgaaaa      900

gaacacugag uucaucaaca caagcgagca uagaaauaga cucacuuuau gaaggaguag      960

auuuuuauac aaguauaaca cgcgcaagau uugaagaguu aaaugcagau uuauucagag     1020

gaacguuaga accgguugag aaagcacuaa gagacgcaaa acuugacaaa ggccaaauac     1080

aagaaauagu auuagucggc ggaucaacua gaauaccaaa aauacaaaaa cuacugcaag     1140

acuucuuuaa uggaaaagaa cucaacaaaa gcauaaaucc agacgaagca gucgcauaug     1200

gugcagcagu acaagcagca auauuaauag gggauaaauc agaaaacgug caagaucuac     1260

uguuacuaga ugucacacca cuaucacuag guauagaaac agcagggggu guaaugacac     1320

cucuaauaaa aagaaauaca accauuccaa caaaacaaac acaaacauuu acaaccuacu     1380

cagauaauca aucaagcguu cuaguacaag uauaugaagg ugaaagagca augacgaagg     1440

auaauaauuu auuaggaaaa uucgaucuca cagguauacc accagcgccc cgaggaguac     1500

cacaaauuga aguaacuuuu gacauagaug caaacggaau cuuaaauguu acagcagcag     1560

auaaaagcac cggaaaagaa aauaaaauca cuauaacgaa ugauaaagga agauuaagca     1620

aagaugauau agauagaaug guacaagaag cggaaagaua caaaagugaa gacgaagcaa     1680

auagagauag aguggcagcc aaaaaugcac uagaaagcua uacauauaau aucaaacaaa     1740

cagucgaaga ugaaaaacua agaggaaaga uaucagaaca agauaaaaac aaaauauugg     1800

acaaauguca agagguaaua aacugguuag auagaaauca aauggcugaa aaggaugaau     1860

augaacauaa acaaaaagaa uuagaaagag uaugcaaucc uauaauauca aaacuauauc     1920

aaggaggacc aggaggagga agcggaggag gaggaagcgg cgcaucaggu ggaccaacca     1980

uagaggaagu agauuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  4964
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt13)

<400>  4964
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aguguuguug guauugauuu aggcuuccaa agcugcuaug      120

uggcaguugc acgagcggga ggcauagaaa caauagcaaa ugaauacagc gaucgaugca      180

cccccgcaug uaucucauuc ggaccuaaaa acagaucaau cggagcagcg gcaaaaucac      240

aaguaauuuc aaaugcgaaa aacacuguac agggauucaa aagauuucau ggaagggcau      300

ucagugaccc auuuguagaa gcugaaaaga guaacuuggc uuaugauaua gugcaacuac      360

caaccggcuu aacaggaaua aaaguaacau acauggaaga agaaagaaac uuuacaacag      420

aacaaguuac cgcaauguua cuuaguaaau uaaaagaaac ugcagaaagc guguuaaaga      480

aaccaguagu agauuguguu gugaguguac ccugcuuuua cacagaugcg gaaaggagau      540

cuguaaugga cgcuacacaa auagcgggac uaaacugcuu aagacuaaug aaugaaacaa      600

cagcagucgc auuagccuac ggcauuuaua aacaagacuu acccgcauua gaagaaaaac      660

caagaaacgu aguuuuugug gacaugggac acucagcaua ucaaguauca gugugugcau      720

uuaauagagg caaacuaaaa guauuagcaa cagcauuuga caccacacua ggaggaagga      780

aauucgauga aguacuugua aaccauuucu gugaagaguu cggcaagaaa uauaaacuag      840

auauaaaauc aaaaauaaga gccuuauuac gacuuucaca agaaugugaa aaauuaaaga      900

aacugauguc agcaaaugcc uccgaucugc cacuaaguau agaaugcuuc augaaugaug      960

uagaugucuc aggaacgaug aaccgcggua aauuuuuaga aaugugcaau gaucuauugg     1020

caaggguaga accaccgcuu agaagcgucc uagaacaaac caaacuaaag aaagaagaua     1080

uauaugcugu agaaauuguc ggaggagcaa caagaauccc agcaguaaaa gagaaaauaa     1140

guaaauucuu uggaaaagaa uuaucaacaa cgcuaaaugc agacgaagcc guaacacgag     1200

gaugcgcauu acagugugcc auacuaaguc cagcauucaa aguaagagag uucaguauaa     1260

ccgacguugu accauacccu auaaguuuaa gguggaauag ucccgcagaa gaagguagcu     1320

cagauuguga aguauuuucu aaaaaucacg cagcaccauu uucaaaagua uuaacauucu     1380

acagaaaaga gccuuuuaca cuagaggcuu auuauucauc accccaagac cuaccauacc     1440

cugauccagc uauagcacaa uucagcguac aaaaagugac accacaaagc gaugggagua     1500

gcucaaaagu aaaaguaaaa guaagaguca acguacaugg aauauuuuca guaaguagug     1560

caagccuagu agaaguacau aaaucagaag aaaaugaaga accuauggaa acagaucaaa     1620

acgcgaaaga agaagagaaa augcaaguug aucaagaaga accccauguc gaagaacaac     1680

aacaacaaac accagcugaa aauaaagcag aaagcgagga aauggaaacc agccaagcug     1740

gauccaaaga caagaaaaug gaucaaccac cccaagcaaa gaaagcaaaa guaaaaacua     1800

gcacagucga cuuaccaaua gaaaaccaac uccuauggca gaucgacagg gaaaugcuaa     1860

aucucuauau agaaaaugag ggaaaaauga uaaugcagga caaacuagaa aaagagagga     1920

acgacgcuaa aaacgcagua gaagaauacg uauacgaaau gagagauaaa cuaucagggg     1980

aauaugaaaa auuuguaucu gaagaugaua gaaacaguuu uacauuaaaa uuggaagaua     2040

cugaaaacug guuauacgaa gauggcgaag accaaccaaa acaaguauac gucgacaaac     2100

uagcugaacu aaagaaucua ggucaaccaa uaaaaauaag auuccaagaa ucagaagaaa     2160

gaccaaaauu auucgaagaa cuaggaaaac aaauacaaca auauaugaaa auaaucucau     2220

cauuuaaaaa uaaagaagac caauacgacc aucuagaugc agcagauaug acaaaaguag     2280

aaaaaucuac uaacgaagca auggaaugga ugaauaauaa auuaaaccuc caaaauaaac     2340

aaucacugac gauggauccc guuguuaaaa gcaaagaaau agaggcaaaa auaaaagaac     2400

uaacaagcac guguaguccc auaauaucaa aaccaaaacc aaaaguagaa cccccaaaag     2460

aagaacagaa aaaugccgaa caaaaugguc caguagaugg acaaggagac aauccaggcc     2520

cacaagcagc agaacaagga acagauacag ccgugccauc agauagugac aagaaauuac     2580

cagaaaugga uauugauuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  4965
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt13)

<400>  4965
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguuguug gcauagaucu cggauuccua aacugcuaua      120

uagccguagc uagaagcggu ggaauagaaa caauagcgaa cgaauacucg gaccgcugca      180

caccagcuug uaucagcuua ggaucccgca ccagagcaau aggcaaugca gcgaaaagcc      240

aaauagugac aaacguacga aauacuauac auggauuuaa aaaacuacac ggaaggaguu      300

ucgaugaccc uauaguacaa acggaaagaa uacgacuccc auaugaacua caaaagaugc      360

cgaauggaag ugcaggagua aaaguaagau accucgaaga agaaagaccc uuugcaauug      420

aacaaguaac uggaauguua cuagcaaaau uaaaagaaac aucggaaaac gcauuaaaaa      480

aaccgguugc cgacugcgua auauccaucc caaguuuuuu uacggaugca gaaagaagaa      540

guguaauggc ggcagcacaa guagcaggau uaaauugccu aaggcucaug aacgaaacga      600

cagcaguagc uuuagcauac ggaauuuaua aacaagauuu gccaccauua gaugagaaac      660

ccagaaaugu aguauucaua gacaugggac acucugccua ucaaguacuc guuugugcau      720

ucaauaaagg caaauuaaaa guuuuagcca caacauucga ucccuaccuc ggcggaagga      780

auuucgacga agcauuagua gauuauuuuu gcgaugaauu caaaacaaaa uacaaaauaa      840

augugaaaga aaacuccaga gcauuacuca gacuauacca agaaugugaa aaacuaaaaa      900

aacuaaugag cgcaaaugca agcgaccucc cccuaaacau agaaugcuuu augaaugacu      960

uggacguauc uucaaaaaug aacagagccc aauucgagca auuaugcgcg ucauuacuag     1020

cccgaguaga accuccacuu aaagcaguaa uggaacaagc aaacuuacaa cgagaagaua     1080

uaucaucuau agagauugua ggaggagcaa caagaauccc cgcaguaaaa gaacagauca     1140

cuaaguuuuu uuuaaaagac auuucuacaa cacucaaugc cgaugaagcc guugcacgag     1200

gaugugcauu acaaugcgcc auauuauccc cagcauuuaa gguaagagaa uucagcauua     1260

cagaccuggu uccauauuca auaacauuaa gauggaaaac aaguuuugaa gacggaucag     1320

gugaaugcga aguauucugc aaaaaccauc cagcaccauu cucuaaagua auuacauucc     1380

auaaaaaaga accauuugaa cuagaagcuu uuuauacuaa ccuacacgaa guaccauacc     1440

cagaugcaag gaucgguuca uuuacaauac aaaacguguu cccgcaaagc gacggagacu     1500

cuaguaaagu gaaaguuaaa guaagaguca auauacaugg aauauuuuca gucgccucag     1560

ccucagugau agaaaaacag aacuuagaag gagaccauag ugacgcuccu auggaaacug     1620

aaacauccuu caaaaaugaa aauaaagaca auauggauaa aaugcaagua gaccaggaag     1680

aaggacauca gaaaugccau gccgaacaua cuccugagga agaaauagau cauacaggag     1740

caaaaacaaa aucggcagua ucagauaaac aagacagauu aaaucaaacu cuaaaaaaag     1800

ggaaaguuaa aucaauagac uuaccaauac aaucgagcuu augcagacag uuaggacaag     1860

accuacuuaa cucauauauu gaaaaugaag gcaaaaugau uaugcaagac aaauuagaaa     1920

aggagaggaa cgaugccaaa aacgcagucg aagaauacgu auaugacuuc agagauagac     1980

uaggaacugu auaugaaaaa uuuauuaccc cagaagacuu aucgaaacua agcgccguuc     2040

uagaagauac agaaaacugg cuguaugagg auggagaaga ucaacccaaa caaguauacg     2100

uugacaaacu acaagaauug aaaaaauacg gacaaccaau ccaaaugaaa uacauggaac     2160

acgaagaaag accaaaagca uuaaaugauc ucggaaaaaa aauccaauua guaaugaaag     2220

uaauagaagc cuaucguaau aaagaugaaa gauacgauca ucuagacccu acagaaaugg     2280

aaaaaguaga aaaauguaua ucagaugcaa ugaguugguu aaauucaaaa augaacgcac     2340

aaaauaaacu aaguuuaacg caagacccug uaguaaaagu cucugaaauc guagcaaaaa     2400

gcaaagaacu ggacaacuuc ugcaacccca uaauauacaa acccaaaccu aaagcagagg     2460

ugccagaaga caaacccaaa gcaaauucug aacauaacgg uccaauggac ggacaaagcg     2520

gaacagaaac aaaaucagac ucaacaaaag auaguucaca acauacaaag ucaucuggcg     2580

aaauggaagu ugacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  4966
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt13)

<400>  4966
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauuaucuu uaguagcggc aaugcuauua cuacuaagcg      120

cagcaagggc agaggaagaa gauaaaaaag aagacgucgg aacaguaguc gguauagacc      180

uaggaaccac auauucaugc gucggaguuu uuaaaaacgg aagaguugaa aucauagcaa      240

acgaucaagg aaacagaauc acaccaucau acguagcguu cacaccugaa ggagaacgac      300

ucauaggaga ugcagcaaaa aaucaauuaa caucuaaccc ugaaaacaca gucuuugacg      360

caaaaagauu gauaggaaga accuggaacg acccuucagu ucaacaagac auaaaauuuc      420

uaccauuuaa aguaguagaa aaaaaaacaa aaccauauau acaaguugau auuggaggcg      480

gucaaacaaa aacauucgca ccagaagaaa uauccgcaau gguacuuaca aaaaugaaag      540

aaacagcuga agcauaccua ggaaaaaaag uaacacaugc cguaguaaca guaccagcau      600

auuuuaauga cgcccaaaga caagcaacaa aggaugcagg aacaauagcu ggucuaaacg      660

ucaugagaau aauaaacgaa ccaacagcag cagcuaucgc auacggacua gauaaaagag      720

aaggagaaaa aaauauacua guauuugauc uaggaggagg aacauucgau guaagcuuau      780

uaacaauaga caacggaguc uuugaaguag uagcuacaaa cggugacaca cauuuaggag      840

gagaagacuu ugaucaaaga guuauggaac acuuuauaaa acuauauaaa aaaaaaaccg      900

ggaaagacgu aaggaaagau aacagggccg uacagaaacu cagaagagaa gucgaaaaag      960

caaaacgagc auuaucauca caacaccaag caagaauaga aauagaaagu uucuaugaag     1020

gagaagauuu uagcgaaacu cuaacgcgag caaaauuuga agagcugaac auggauuuau     1080

uuagaaguac caugaaacca guacaaaaag uacucgaaga cagugauuua aaaaaaagug     1140

acauagacga aauaguccua guaggagguu caacccgaau ccccaaaaua caacaacucg     1200

ucaaagaauu uuucaacgga aaagaaccga gccgaggaau aaacccugac gaagcaguag     1260

cauauggcgc agcaguucaa gcaggcguau uaagcggaga ucaagauaca ggagauuuag     1320

uacuacuaga cguaugucca cuaacucuag gaauagaaac agucggagga guaaugacca     1380

aauuaauacc uagaaacaca guaguaccga caaaaaaauc acaaauuuuc uccacagcaa     1440

gcgacaauca accaacagua accauaaaag uauacgaagg cgaaagacca uuaacaaaag     1500

auaaccauuu auuaggaaca uuugauuuaa cagguauccc accugcccca cgaggagucc     1560

cacaaauaga aguuacauuu gaaauagaug uaaaugguau ccucagaguc acagcggaag     1620

auaaaggcac uggaaauaag aauaaaauua cuauaacaaa cgaccaaaau agauuaacuc     1680

ccgaagaaau agaaagaaug guaaaugaug cggaaaaauu cgccgaagag gacaaaaaac     1740

uaaaagagag aauagauacc agaaacgagu uagaaucaua cgcauacucc cuuaagaauc     1800

aaauuggaga uaaagaaaaa uuaggcggca aauugagcuc agaagacaaa gaaaccaugg     1860

aaaaagcagu agaagaaaaa auagaauggc uugaaagcca ccaggaugca gauauagaag     1920

auuucaaagc aaaaaaaaaa gagcuagagg aaaucguaca accaauaauu ucaaaacuau     1980

acggaagugc agggccacca ccaacaggag aagaagacac cgcagaaaaa gaugaacuuu     2040

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  4967
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt13)

<400>  4967
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcaccac gugaacuugc agucgguaua gaucuaggaa      120

caacauauuc cuguguagga guauuucaac aagggagagu agaaauauua gcaaacgauc      180

aaggcaauag aacaacacca ucauauguag cauuuacuga cacagaaaga uugguaggag      240

augcagccaa aagucaagca gcauuaaauc cacauaacac aguguucgac gcgaaaagac      300

uaauugguag aaaauuugcg gauacaacag uccaaaguga caugaagcau uggccauuua      360

ggguaguguc ugaaggugga aaaccaaaag uaagaguaug cuauagaggu gaagauaaaa      420

cauuuuaucc agaagaaauu ucaucaaugg uauuaagcaa aaugaaagag acagcagaag      480

cauaccuugg acaaccagua aaacaugcug uaauaacagu ucccgcauac uucaaugaua      540

gccaaagaca agcaacaaaa gaugcuggag caauagcugg auuaaacgug cuaagaauua      600

uaaaugaacc aaccgccgcg gcaauugcau auggauuaga uagaagagga gcaggagaaa      660

gaaacguauu aauauucgau cuaggaggag gaacauuuga cguaucaguc uuaucaauag      720

acgcaggcgu auucgaagua aaagcaacag cuggugauac ucacuuagga ggagaagauu      780

ucgauaacag auuaguuaau cacuucaugg aagaauuucg acgaaaacau ggcaaagauc      840

uauccggcaa uaaaagagca uuaagaagac uacgaacagc gugugaaaga gcaaaaagaa      900

cauuauccuc aucuacccaa gcuacauuag aaauagauag ccuauucgaa gggguagauu      960

uuuacacuuc cauaacaaga gcucgcuucg aggaacuaug cucagauuua uuuagaucua     1020

cuuuagaacc uguagaaaaa gccuuacgug acgcaaaauu agauaaagca caaauacaug     1080

acgucguauu aguaggugga aguacccgaa uaccaaaagu acaaaaacua uuacaagauu     1140

ucuuuaacgg aaaagaacua aacaaaucaa uuaauccaga ugaagcaguu gcuuacggcg     1200

cagcaguaca ggcagcagua uuaaugggag auaaauguga aaaaguacaa gauuuguuac     1260

uucuagacgu ggcaccccua agccuaggau uagaaacagc aggaggagua augaccacau     1320

uaauacaaag aaaugcaaca auaccuacua aacaaacaca aacauuuaca acauauagug     1380

acaaucaacc ugggguauuc auacaaguau augaagguga aagagcaaug acaaaagaua     1440

auaauuuacu agguagauuu gaauuaucag ggauuccacc agcaccacga ggaguaccgc     1500

aaauagaggu gacuuuugac auagacgcaa auggcaucuu aagcguaaca gcaacagaua     1560

gaagcacagg aaaagcaaac aaaauaacaa uaacaaauga caaaggaagg uuaagcaaag     1620

aggaggucga aaggauggua caugaagcag agcaauauaa ggccgaagau gaagcccaaa     1680

gagacagagu agcagcuaaa aauucacuag aagcacaugu guuucacgua aaagggagcu     1740

uacaagaaga gaguuuaaga gauaaaauac cagaagaaga uagacgaaaa augcaagaua     1800

aaugcagaga aguauuagca uggcuagaac auaaucaacu ggcagaaaaa gaagaauaug     1860

aacaucaaaa acgagaauua gaacaaauau gcagaccaau auucucaagg cuauauggcg     1920

gaccaggagu accaggagga aguucuugug gaacucaagc uagacaagga gacccuucua     1980

caggaccaau aauugaagaa guagauuaag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  4968
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt13)

<400>  4968
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcaccca gagaauuagc cguaggaaua gaccuaggaa      120

cuacauauag cugugucgga guauuucaac aaggaagagu ugaaauauua gcaaaugacc      180

aaggaaauag aacaacaccu ucauauguag cauucacaga cacagaaagg uuaguaggag      240

augccgcgaa aagccaagca gcauuaaacc cacacaauac aguauucgau gcaaaaagac      300

ucaucggaag aaaauuugca gauacaacag uacaaucaga uaugaaacau uggccauuuc      360

aaguagucuc agaaggcgga aaaccaaaag uaagaguaug uuacagagga gaagauaaaa      420

cauuuuaucc agaagaaaua ucaaguaugg uauuaucaaa gaugaaagaa acagcagaag      480

cauaucuagg ccaaccagua aaacaugcag uaauaacagu accaacuuau uucucaaauu      540

cacaaagaca agcaacaaaa gaugcuggag caauugcagg ucuaaaagua uuaccaauca      600

uaaaugaagc uacagcugca gcaauagcau auggccuaga uagaagagga gcaggaaaaa      660

gaaauguauu aauauuugau uuaggaggag gaaccuuuga cguaucagua uuaucaauag      720

augcaggagu auuugaagua aaagcaacag ccggagauac acaucuagga ggagaagauu      780

ucgacaacag auuaguuaau cacuucaugg aagaauuuag aagaaaacac ggaaaagacu      840

uaucagguaa uaaaagagca cuuagaagau uaagaacagc augugaaaga gccaaaagaa      900

caccaucaag cucaacacaa gcgacauuag aaaucgauuc acuauucgaa ggaguagauu      960

uuuauaaauc aauaacuaga gcccgauuug aagaauuaug uucagacuua uuucgaagca     1020

cacuagaacc aguagaaaaa gcacuaagag augcaaaacu agacaaagca caaauacacg     1080

acuucguauu aggaggagga cuacacaguc auccacaagg agcugaagua gcugcaggau     1140

uauuacaaag acaaggagca gaacaagaac accaaccuua aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  4969
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt13)

<400>  4969
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaaaagguc cugcuguagg aauugacuua ggaacgacau      120

auucgugugu uggugucuuc caacauggga aaguagaaau uauagcaaac gaucaaggaa      180

accgaacaac accaucauac guagcuuuua cagauacaga aagauuaauc ggagacgcgg      240

cuaaaaauca aguagcaaug aauccaacaa acacagucuu ugacgcaaaa cgacuaauag      300

gaagaagauu ugaugaugca guaguucaaa gcgauaugaa acacuggcca uuuaugguag      360

uaaaugacgc aggaaggcca aaaguacaag uagaauacaa aggagaaaca aagagcuucu      420

auccggaaga aguaucaagc augguauuaa caaaaaugaa agagauagca gaggcauacu      480

uaggaaaaac aguaacaaac gcaguaguca caguuccagc auauuucaac gauagccaaa      540

gacaagcaac aaaagacgca gguacaauag caggauuaaa uguacuccgg auaauaaacg      600

aaccaacagc ugcugcaauc gcguauggac uagauaagaa aguaggcgca gaaagaaaug      660

uauuaaucuu cgacuuagga ggaggaacau ucgauguauc uauucuaaca auagaagacg      720

gcauauucga aguaaaaagc acagccggcg acacacacuu aggaggagaa gauuucgaua      780

accgaauggu aaaccauuuc auagccgagu ucaaaaggaa acacaagaaa gacauaagug      840

aaaauaaaag agcaguacgc cgauuaagaa ccgcauguga aagagcaaaa agaacucuaa      900

guucaagcac acaagcgagu auagaaauag acaguuuaua ugaagguaua gauuuuuaua      960

caucaauaac aagagcaaga uucgaagaac uuaacgcaga ccuauuuaga ggaacacuag     1020

acccaguaga aaaagcacua agagaugcaa aauuagacaa aagccaaaua caugauauag     1080

uauuggucgg aggaucgacu agaaucccaa aaauacaaaa acuauuacaa gacuucuuua     1140

acggaaaaga acucaauaaa ucgauuaauc cagaugaagc agucgcauau ggagcugcgg     1200

uacaagccgc gauauuaagc ggagacaaau ccgaaaacgu ccaagaucua uuacucuuag     1260

acguaacacc ucugucgcua ggaauugaaa cagccggugg gguaaugaca guacuaauaa     1320

aaagaaacac cacaauacca acuaaacaaa cacaaacauu uacuacauac ucagauaauc     1380

aaccaggagu ccuaauucaa guuuacgaag gggaacgugc aaugacaaaa gacaauaauu     1440

uacucggaaa auuugaacua acaggaauac caccagcacc aagaggagua ccacaaauag     1500

aaguaacauu ugauauagau gcaaauggaa uacuaaacgu aagugcggua gauaaaagca     1560

cagguaaaga aaacaaaaua acaauaacua acgacaaagg cagauuauca aaagaagaua     1620

uagaaagaau ggugcaagaa gcagaaaaau auaaagcaga agacgaaaaa caaagagaua     1680

aaguaaguag uaaaaauuca uuagaaucau acgcauuuaa uaugaaagca acgguagaag     1740

augaaaaauu gcaaggaaaa auaaacgaug aagauaagca gaaaauuuua gacaaaugua     1800

acgaaauuau aaauugguua gauaaaaauc aaacagcaga gaaagaggaa uuugaacauc     1860

aacaaaaaga auuggaaaag gucugcaauc cuauaauaac caaauuauac caaucugcgg     1920

gaggaaugcc aggcggaaug ccaggaggau ucccaggugg aggagcucca ccaagcggag     1980

gagcaagcag uggaccaaca auagaagaag ucgauuaagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  4970
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt13)

<400>  4970
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucagugcaa gcagagcugc cgcagcaaga uuaguaggag      120

cggcagcaag cagaggacca accgcugcua gacaucaaga uaguuggaau ggauuaucac      180

acgaagcauu uagacucgua aguagacgag acuaugcaag cgaggcaaua aaaggcgcag      240

uaguagggau cgauuuaggg acgacaaacu caugcguagc agucauggaa ggaaaacaag      300

caaaaguacu agaaaaugca gaaggagcga gaacaacacc aucaguagua gcguuuacug      360

cagauggaga aaggcuagua ggcaugcccg cuaaaagaca agcaguaaca aauccaaaua      420

auacauuuua ugcaacaaaa agauuaauag gaagaagaua ugaugaccca gagguacaga      480

aagacaucaa aaauguaccu uuuaaaauag uaagagcaag uaacggagac gcauggguag      540

aagcacaugg uaaacuauau aguccgucgc aaauaggagc auuuguucuu augaaaauga      600

aagaaacggc agaaaauuau cuagggcaua cagccaagaa cgcaguaaua acaguacccg      660

cauauuucaa cgauucacag cgucaagcaa cgaaagaugc gggacaaauu agugggcuga      720

auguauuaag aguaauaaac gaacccacag cugcagcccu agcguaugga cucgauaaau      780

cagaagacaa aguaaucgca guauaugauu uagguggggg aaccuuugac auuucaauau      840

uagaaauaca aaaaggcgua uuugaaguaa aaaguacaaa uggagauaca uucuuaggag      900

gagaagacuu cgaucaagcu cuauuacgac auauagugaa agaguucaaa agagaaacag      960

gaguugacuu aacaaaagau aacauggcac uacaaagagu aagagaagca gcugaaaaag     1020

cgaaaugcga acuaaguagu aguguacaaa cagacauaaa cuuaccauac uuaacaaugg     1080

acucaucagg gccaaaacau cuuaacauga aacugacuag agcacaauuc gaaggaauag     1140

ucaccgaucu aauacguagg accauugcac caugccagaa agcaaugcag gacgcagaag     1200

uaucgaaaag cgauauagga gaaguaauau uaguuggggg aaugacaaga augccuaaag     1260

uacaacaaac aguacaagau uuauuuggaa gggcaccauc aaaagcagua aacccagacg     1320

aagcaguggc gauaggagcc gcaauacaag gaggaguacu agcaggagac guaacugaug     1380

uuuuauuacu agauguaacc ccacuaaguu ugggaauaga aacauuagga ggaguauuua     1440

caaaacuaau aaauagaaau accacaauac cuacaaagaa aucucaagua uuuucaacag     1500

cagcagacgg ccaaacacaa guggaaauaa aaguauguca aggcgaaaga gaaauggcag     1560

gagacaauaa acuguuagga caauuuacuu uaauagguau accaccagca ccaaggggag     1620

uaccucaaau ugaaguaaca uucgacauag acgcaaaugg aauaguccau guaucagcga     1680

aagauaaggg cacagggagg gaacaacaaa uaguaauaca aaguagcgga ggacugagua     1740

aagacgauau agaaaauaug gucaaaaaug cugaaaaaua ugcugaagag gauaggagga     1800

agaaagaaag gguagaagcg guaaauaugg cagaaggaau aauacaugac acagaaacaa     1860

aaauggaaga auuuaaagau caauuaccag cggaugaaug uaauaaacuc aaagaagaaa     1920

uaaguaaaau gagagaguua cuugcaagaa aagauucaga aacgggagaa aauauacgac     1980

aagcagcaag uucacuacaa caagcuaguc uaaaauuauu cgaaauggcc uauaagaaaa     2040

uggcaucgga acgagaagga ucaggaucau cugguacagg ggaacaaaaa gaagaucaaa     2100

aagaagaaaa acaauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  4971
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt13)

<400>  4971
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcugauaaag aagccggagg aucugauggc ccuagagaaa      120

ccgcaccaac uucagcauau agcagccccg ccagaucauu aggagauaca ggcauaacuc      180

ccuuaucacc aucccauaua guaaacgaua cagauaguaa ugucuccgaa caacaaucau      240

uuuugguugu uguagcaguc gauuucggua caacaagcuc cggauacgca uauuccuuca      300

caaaagaacc ggaauguaua cauguuauga gaagauggga aggcggcgac ccaggaguua      360

guaaccaaaa gacuccaacu acaauccucu uaacaccgga aaggaaauuc cauucauucg      420

gauaugccgc acgcgauuuu uaccacgauu uagacccaaa cgaagcgaaa caaugguuau      480

aucuagaaaa auuuaaaaug aaacuacaua ccacaggaga ccuuacuaug gauacagacc      540

uaacagcugc aaauggaaag aaaguaaaag cauuagaaau cuuugcauac gcguuacaau      600

acuuuaaaga acaagccuua aaagaauuaa gcgaccaagc uggaucagaa uuugaaaauu      660

ccgacguacg augggucaua acgguaccug caauauggaa acaaccagca aaacaauuca      720

ugagacaagc cgccuaucaa gcuggacuag cgucaccaga aaacagcgaa caacuaauaa      780

uagcacuaga accagaagca gcaucaaucu auuguagaaa acuaagauua caucaaauga      840

uagaacuauc aucaaaagcu gcaguaaaug gauauucagg aagugacacc guaggugcag      900

gauuuacuca agccaaagaa cacauaagaa gaaauagaca aucuagaacc uuucuagucg      960

aaaauguaau uggcgaaaua uggucugaau uagaagaagg agacaaauau gucguaguug     1020

acuccggugg aggaacagug gaucucaccg uccaucaaau acgacuacca gaaggacauc     1080

uuaaagaacu cuacaaagcu acaggaggac cauauggcuc auuaggcgua gauuaugaau     1140

uugaaaaacu gcuauacaaa aucuucggag aagacuuuau agaacaauuu aaaaucaaaa     1200

gaccagcagc auggguagau uuaaugauag cauucgaauc aagaaaaaga gcugcagcac     1260

cagaucgaac uaauccguua aauauaacgu uaccauucuc auucauugac uacuauaaaa     1320

aguuuagagg ucauaguguu gaacaugcac uaagaaaauc gaauguagau uuuguaaaau     1380

ggucaaguca aggcauguua agaaugucac cagaugccau gaaugcauua uuuaaaccaa     1440

cuauagauuc aauaauagaa cauuuaagag acuuauucca aaaaccagaa guaucuacag     1500

uuaaauucuu auuccuagua gggggauuug cagaagcucc acuucuacaa caagcagugc     1560

aagcagcauu cggcgaccaa ugucgaauaa uaauaccuca agacguaggc cucacaauac     1620

uaaaaggagc gguauuauuu ggauuagauc cugcagucau aaaaguaaga agaucaccuc     1680

uaacauacgg uguaggagua cuaaacaggu acguagaagg aaaacaccca ccugaaaaac     1740

uuuuagucaa agacggaacu agauggugca cagauguauu ugauaaauuc auaucagcag     1800

aucaaucagu agcauuagga gaacugguaa aacgaucaua cacuccugcu aaacccagcc     1860

aauuaguaau cguaauaaau auauauucaa gugaacauga uaaugucuca uuuauaacag     1920

auccaggagu aaagaaaugc ggaacauuga gauuggaccu cacaggaaca ucaggaacag     1980

cuguaccagc aagacgagaa auucaaacac uaaugcaauu uggagauacc gaaauaaaag     2040

caacugcaau agauauagcc accagcaaaa guguaaaagu gggaaucgau uucuuaaauu     2100

auuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  4972
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt13)

<400>  4972
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuagcaguac cugaaauggg auuacaaggu cuauauauag      120

guagcucgcc agaacgauca ccaguaccaa guccgccggg aucaccucgc acacaagaaa      180

gcuguggaau ugcaccacua accccuucuc aaucaccaaa gccagaaguu agagcacccc      240

aacaggcuuc auuuucugua guaguagcaa uagacuuugg caccacaucc ucaggcuaug      300

ccuucagcuu ugcaucagac ccagaagcga uacauaugau gaggaaaugg gaaggaggag      360

auccaggggu agcacaucag aaaacaccua cuugcuuauu acuaacacca gaaggcgcau      420

uucauaguuu uggauauaca gcaagagacu auuaucauga ucuggauccu gaagaagcgc      480

gugauugguu auauuuugaa aaauuuaaaa ugaaaaucca uucagcaaca gaucuaacuu      540

uaaaaacaca auuagaagcu gucaauggca aaacaaugcc agcauuagaa guauuugccc      600

augcacuaag auuuuuccga gaacaugcac uacaagaacu uagagaacaa uccccaaguu      660

uaccugagaa agauacagua agauggguau uaacagugcc ggcaauaugg aaacaaccug      720

cuaaacaauu caugagggaa gccgccuauu uagcaggauu gguuucacga gaaaacgcag      780

aacaacuauu gauagcuuua gagccagagg cggcaagugu auauuguaga aaacuaagau      840

uacaucaacu acuagauuua ucaggcagag cuccaggagg agguagauua ggagaaagac      900

gauccauuga uucuaguuuu agacaagcua gagaacaacu aagaagaagc agacauucaa      960

gaacauuccu uguagaaagu ggaguaggag aauuaugggc agaaaugcaa gcaggagaua     1020

gauauguagu ugcagacugu ggaggaggaa cuguagaccu cacaguucau caacuagaac     1080

aaccacaugg uacccuaaaa gaauuauaua aagcgagugg cggcccauac ggagcaguag     1140

gcguagauuu agcauuugaa caauuacucu gucgaauauu uggagaagau uucauagcua     1200

cuuuuaaaag acaaagacca gcugcauggg uagaucuaac uauagcuuuc gaagcaagaa     1260

aaagaacagc cggaccucau agagcaggag cauuaaauau aucucuacca uuuaguuuua     1320

uagauuuuua cagaaaacaa cggggacaua acguagaaac ggcauuacga agaucaagug     1380

ucaacuucgu aaaaugguca ucacaaggua uguuaagaau guccugugaa gcaaugaaug     1440

aacuauuuca acccacugua agcggaauaa uacaacacau agaagcauua uuagcaagac     1500

ccgaaguuca aggaguaaaa uuacuauuuc uaguaggagg guuugccgaa ucggcaguuc     1560

uacaacaugc aguacaagcu gcguuaggcg cacgaggauu acgaguagua guaccccacg     1620

auguugggcu uacaauucug aaaggagcug uauuauuugg acaggcacca ggaguaguca     1680

gaguuagaag aagcccacua acauaugggg uaggaguacu uaacagauuu guaccaggca     1740

ggcauccucc agaaaaauua uuaguacgag acggaagacg uugguguaca gauguauucg     1800

aaagauucgu ugcagcugaa caaagcguug cauuaggaga agaaguaaga cgaucauauu     1860

gcccagcuag accaggucaa agaagaguuc uaauaaacuu auauuguugc gccgcagaag     1920

augcaagguu uauuacugau ccuggaguuc gaaaaugugg ugcacuuagc cuagaacuag     1980

aaccggccga uuguggacaa gauacagccg gagcaccacc agguagaaga gaaauaagag     2040

cugcuaugca auucggagac accgaaauaa aagucacagc aguagauguc agcacaaaua     2100

gaucagugcg agcuaguaua gacuuucuau caaauugagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  4973
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt13)

<400>  4973
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacgagaaa ugaccauauu aggaagcgcc guauuaacau      120

uauuacuagc gggauauuua gcacaacaau aucuaccccu acccacacca aaaguaaucg      180

gaauagacuu aggaacaaca uauuguagug uaggaguuuu cuucccagga accggaaaag      240

ucaaaguaau accagacgaa aacggacaca uaucaauucc aucaauggua ucauuuacug      300

auaacgacgu auauguagga uacgaaucag uagaauuagc cgauagcaau ccacaaaaca      360

cuauauauga cgcaaaaaga uucauaggca aaauauuuac agcagaagaa cuugaagcug      420

aaauaggaag auaucccuuu aaaguacuaa auaaaaacgg aaugguagaa uucucaguua      480

caucaaauga aacaauaaca gucaguccag aauacguagg uagcagauua cuacuaaaac      540

uaaaagaaau ggcagaagca uacuuaggaa ugccaguagc aaaugccgua auaucuguac      600

cagcagaauu cgauuuaaaa caacgaaauu caacaauaga agcagcuaau cuagcaggac      660

uaaaaauauu aagaguuaua aacgaaccca cagcagcagc aauggccuau ggauuacaca      720

aagcugacgu auuucaugua cuaguaauag aucuaggugg agguacauua gacguaagcu      780

uacuaaauaa acaaggaggc auguuucuua cacgagcaau gucaggcaac aacaaauuag      840

gaggucaaga cuuuaaccaa agacuacuac aauaucucua caaacaaauu uaccaaacuu      900

auggauuugu uccuucaaga aaagaagaaa uacaucgauu acgacaagca guagagaugg      960

uaaaacuaaa uuuaacacua caucagagug cacaacuuuc cgucuuauua acaguugaag     1020

aacaagaucg aaaagaacca cacaguucag acaccgaacu uccaaaagau aaauuaagcu     1080

cagcagauga ccauagaguu aacagcggcu uuggaagagg auuaucagac aaaaaaagcg     1140

gagaaagcca agugcuguuu gaaaccgaaa uaagcagaaa auuauucgau acacuuaacg     1200

aagaccuauu ccaaaaaaua uuaguaccaa uccaacaagu acuaaaagaa ggucaucuag     1260

aaaaaacaga aauagaugag guaguauuag uaggaggauc aacacguaua cccagaauaa     1320

gacaaguaau acaggaauuu uucggaaaag auccaaauac aucaguagac ccagauuuag     1380

cgguuguuac aggagucgca auacaagcag gaauagaugg cggaagcugg ccauuacaag     1440

uauccgcacu agagauccca aacaaacauc uacaaaaaac caauuucaau uaaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4974
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt13)

<400>  4974
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagcaauag gaguacauuu aggauguaca agugcaugug      120

uagcaguaua uaaagaugga agagcaggag uaguagccaa ugaugcaggg gauagaguaa      180

caccagcggu aguagcuuau ucagaaaaug aagaaauagu aggauuagcu gcaaaacaau      240

caagaauaag aaauauuagu aacaccguaa ugaaagugaa acaaauacua ggaagaucuu      300

caucagaucc ccaagcacaa aaauauauag cagaaucaaa augucuagua auagaaaaaa      360

auggcaaacu aagauaugaa auagauacag gcgaagaaac aaaauuugua aacccugaag      420

augucgcuag acuaauauuc ucaaaaauga aagaaacagc acauucagua cuaggaucag      480

augcaaauga cguaguaaua accguaccau uugauuuugg agaaaaacaa aaaaaugcau      540

uaggagaagc agcaagagca gcaggauuua acguguuacg acuuauacau gaacccucag      600

cagcauuauu agccuaugga auaggucaag acucaccaac aggcaaauca aauauauuag      660

uauuuaaauu aggaggaacu agucuaucac ucucaguaau ggaaguaaau ucaggaauau      720

acagaguuuu aucaacuaau acagaugaua auauuggagg agcacauuuu acagaaacau      780

uagcucaaua ccuugcaagu gaauuucaaa gaaguuuuaa acacgauguc agaggaaaug      840

caagagcaau gaugaaacua acgaauucag cagaaguagc aaaacauuca uuaucaacau      900

uagggucugc caauuguuuc cuagauaguc uuuaugaagg gcaagacuuu gacuguaaug      960

uaagucgagc aagauuugaa cuacuguguu caccccuguu uaacaagugc auagaagcaa     1020

uaaggggauu acuagaucaa aauggcuuca ccgcagauga caucaauaaa guaguacuau     1080

guggaggaag cucaagaaua ccaaaacucc aacaauuaau aaaagauuua uuucccgcug     1140

uagaacuacu aaauaguaua cccccagaug aaguaauacc aauaggugcc gcaauagaag     1200

caggcauauu aauaggcaaa gagaaucuac uaguggaaga cagucuaaug auagaaugua     1260

gugcaagaga cauauuagua aaagggguag augaaagugg agcaagcaga uuuacaguau     1320

uauuccccag cggaacaccu cuaccagcaa gaagacaaca uacucuacaa gcgccagguu     1380

caauaucauc aguuugccua gaacuauacg aaucagacgg uaaaaacuca gcaaaagaag     1440

aaacaaaauu cgcucaagua guacuacaag auuuggacaa aaaagagaau ggacuaagag     1500

auauucuagc cguauugacu augaaaagag auggaucacu acacguaaca uguacagacc     1560

aagaaacagg aaaaugugaa gcaaucucua uagaaauagc cucauaagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  4975
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt13)

<400>  4975
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aguguugugg ggcuagacgu agggagccaa aguugcuaua      120

uagcaguagc cagagccgga ggaauagaaa cgauagcaaa ugaauucuca gauagaugca      180

ccccaagugu aauaucauuc ggaucaaaaa acaggacgau aggaguggca gccaaaaauc      240

aacagauaac gcacgcaaau aacacaguca gcaacuuuaa aagauuucac ggaagagcau      300

uuaacgaccc auuuauacaa aaagaaaaag agaaucuaag uuacgacuua gucccccuaa      360

aaaauggagg agugggaaua aaaguaaugu auaugggcga agaacaccuu uuuucaguug      420

aacaaauaac ugcgaugcua uuaacaaaac uaaaagaaac agcagaaaac ucauuaaaaa      480

aaccaguaac agacugcgua auaucaguac caucauucuu uacagacgcu gaacgacgaa      540

guguucuaga cgcagcacag auaguagguu ugaauugucu aagacugaug aacgacauga      600

cagcaguagc guuaaacuac ggaauauaca aacaggaccu accaagcuug gacgagaaac      660

cuagaauagu aguauucgua gacauggggc acucugcauu ccaaguuagu gcaugcgcau      720

ucaauaaagg uaaacucaaa guauuaggaa cagcauuuga cccauucuua ggaggcaaaa      780

acuuugacga aaaacuuguu gaacauuucu gcgcggaauu caaaacaaaa uauaaauugg      840

acgccaaaag caaaauaaga gcccuuuuac gacuauacca agagugcgaa aaacuaaaaa      900

aacuaaugag uaguaauuca acugaccuac cacucaauau ugaguguuuc augaaugaua      960

aagauguaag uggcaaaaug aacagaucuc aauucgaaga auuaugcgcc gaauugcuac     1020

agaaaauaga gguaccacua uauagccucc uagaacaaac acaucuaaaa guagaagaug     1080

uuagugcagu ggaaauagua ggaggcgcua caagaauacc ugcaguuaaa gaaagaaucg     1140

cuaaauucuu cggaaaagau auauccacaa cacuuaaugc agacgaagca guagcucgcg     1200

gcugcgcucu ccaaugugcc auucuaaguc cagccuucaa agucagagaa uucucuguaa     1260

cugacgcagu uccguucccu auaucacuua uauggaacca cgacagugaa gauacugaag     1320

gagugcauga aguauucagc aggaaccaug ccgcuccuuu cagcaaagua uuaacuuucu     1380

uacgaagggg accauucgaa uuagaagcau uuuacucaga uccacaagga guaccauacc     1440

cugaagcaaa aauaggccga uucguaguac aaaacgucag cgcacaaaaa gauggagaaa     1500

aaucaagagu caaaguaaag guacguguaa auacccacgg uauuuucaca auaucaacag     1560

cauccauggu agaaaaagua ccuacagaag aaaaugaaau gucaagcgaa gcagauaugg     1620

aaugcuuaaa ucaaagacca ccagaaaacc cagauacaga caaaaacgua caacaagaua     1680

acucagaagc aggaacacaa ccacaaguac aaaccgaugc ucaacaaacc ucacaaucac     1740

cuccaagccc agaacuuacu ucugaagaaa acaaaauccc agacgcagau aaagccaacg     1800

aaaaaaaagu cgaccaacca ccagaagcua aaaaaccaaa aauaaaagua guaaacguag     1860

aacugcccau agaagcaaac cuaguauggc aacuaggaaa agauuuauua aacauguaca     1920

uagaaacuga aggcaaaaug aucaugcaag auaaacuaga aaaagaacgc aaugacgcaa     1980

aaaacgcagu agaagaauau guauaugaau uuagagacaa auuaugugga ccauaugaaa     2040

aauucauaug cgaacaagau caccaaaauu uccuacgacu acucacugaa acagaagacu     2100

gguuauauga agaaggagaa gaccaagcaa aacaagcuua cguagacaaa cuggaagaac     2160

uaaugaaaau agguacgccu guaaaaguac guuuccaaga agcagaagaa agaccgaaaa     2220

uguuugaaga auuaggacag agacuccaac acuaugcaaa aauagcugca gacuuccgaa     2280

acaaagauga aaaauauaac cacauagaug aaagcgaaau gaaaaaaguu gaaaaaucag     2340

ucaacgaagu aauggaaugg augaacaacg uaaugaaugc acaagcaaaa aaaagucuag     2400

accaagaccc aguagucagg gcgcaagaga uaaaaacgaa aaucaaagaa uuaaauaaca     2460

cuugcgaacc cgucguaacg caaccaaaac cuaaaauaga aucaccaaaa cuagagcgca     2520

cgccuaaugg uccaaacaua gacaaaaaag aagaggaccu agaagauaaa aauaacuuug     2580

gugcagaacc cccccaucaa aacggagaau gcuauccaaa cgaaaaaaau aguguaaaua     2640

uggaucuaga cuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  4976
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt13)

<400>  4976
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcugauaaag uaagaagaca aagacccaga aggagaguuu      120

guugggcucu aguagcagua uuacuggcag auuuauuagc cuuaucagau acccuugcag      180

uaauguccgu agaccuagga agugaaagua ugaaaguagc aauaguuaaa cccggaguac      240

caauggaaau aguccuuaac aaagaaucua gaaggaaaac uccaguuaua guaacacuaa      300

aagaaaauga acgauucuuc ggcgacagug cagcaucaau ggccaucaaa aauccaaaag      360

caacauuaag auacuuucaa caucuucuug gcaaacaagc ugauaauccu caugucgcau      420

uauaucaagc aagauucccc gaacacgaac uaacuuuuga cccacaacgu caaacuguac      480

acuuucaaau aaguucacaa cuacaauuua guccagaaga aguacucgga augguccuga      540

auuauucaag aucauuagca gaagauuucg cagaacaacc uauaaaagac gcaguaauaa      600

ccguuccugu guucuuuaac caagccgaaa ggcgagcagu auuacaagca gcucgaaugg      660

caggauuaaa agucuuacaa uugauaaaug auaauacagc aacagcacuu aguuacgggg      720

uauuuagacg aaaagauauc aauacgacag cucaaaauau aauguuuuau gacaugggaa      780

guggcucaac agucugcaca auaguaacau aucaaauggu caaaacaaaa gaagccggga      840

ugcaaccaca acugcaaaua cgagguguag gauucgauag aaccuuaggg ggacuagaaa      900

uggaauuaag auuacgagaa agauuagcag gauuauuuaa cgaacaaagg aaaggccaac      960

gugcaaagga uguaagagaa aauccaagag cgauggcaaa acuccugaga gaggcuaaua     1020

ggcuaaaaac ggugcuaagc gcaaaugcgg accauauggc acaaauagaa ggguuaaugg     1080

augacguaga cuuuaaagcc aaaguaacac gcguagaguu cgaagaauua ugugcugauc     1140

uauuugaaag aguaccgggu ccaguucaac aagcguuaca aucggcagaa augucacuug     1200

augaaauaga acaaguaauu uuaguagggg gcgcuaccag gguuccuagg guacaagaag     1260

uccuauugaa agccgugggg aaagaagaau uagguaagaa uauaaacgca gaugaagcug     1320

cugcaauggg ugcaguguau caagcagcag cacuaagcaa ggcauuuaag gugaaaccgu     1380

ucguuguaag ggaugcugua gucuauccaa uauuaguaga auuuacucgc gaaguagaag     1440

aagaaccagg aauacauucc uuaaaacaua auaaaagagu cuuauucagc aggaugggac     1500

ccuauccuca gagaaaagua auaaccuuca accgauacag ucaugacuuc aauuuccaca     1560

uaaacuaugg agauuuagga uuucuugguc cggaagacuu aagaguauuu ggaagucaaa     1620

aucuaacaac cguaaaauua aaaggcgugg gagacucauu uaagaaguau cccgauuacg     1680

aaucaaaagg aauuaaggca cauuuuaacu uagacgagag cggagucuua agccuggaca     1740

gaguggaauc aguauucgaa acguugguug aagauucagc ugaagaagaa aguacacuaa     1800

cgaaauuggg aaacaccaua aguucucuau ucggaggagg cacaacucca gaugcaaaag     1860

aaaaugguac agauacuguc caagaagaag aagaaucacc agcagaagga uccaaggacg     1920

aaccaggaga gcaaguugaa cuuaaagaag aagcagaagc acccguugaa gauggaucac     1980

aaccuccacc acccgaaccg aaaggagacg ccacgccgga aggagaaaaa gcaacugaaa     2040

aagaaaaugg agauaaauca gaagcacaaa aaccaucuga aaaagccgag gcaggaccag     2100

aagguguagc ucccgcuccg gaaggugaaa agaaacaaaa accagcacga aaaagacgca     2160

uggucgaaga aauaggagua gaauuaguag uuuuagacuu accugaucuc ccagaagaca     2220

aacucgcaca aucaguacaa aaacuacaag aucuaacauu gagagaucug gagaaacaag     2280

aaagagaaaa agcagcuaau agucuagagg cuuucauuuu cgaaacccaa gacaaauuau     2340

accaaccuga auaccaggaa guuuccacag aagaacaaag ggaagaaauc agugguaaau     2400

ugagcgcagc uaguacaugg uuagaagaug aaggaguugg agcaacgaca guaauguuaa     2460

aagaaaaauu agcagaauua aggaaauuau gucaaggacu cuucuuuaga gucgaagaaa     2520

gaaagaaaug gcccgagaga uugucagcau uagacaauuu auuaaaccau uccagcaugu     2580

ucuuaaaagg ugccagacuu auaccagaaa uggaucagau auuuacagaa guggaaauga     2640

cuacacuaga aaaaguaauu aacgaaaccu gggcauggaa aaaugcaaca cuagcagaac     2700

aagccaaauu accggcgacg gagaaaccag uacuauuauc gaaagauaua gaagcaaaaa     2760

ugauggcucu agaccgagaa guccaauacc uuuuaaacaa agccaaauuu acaaaaccaa     2820

ggccaagacc uaaagacaaa aauggaacaa gagcggaacc accacuaaac gcgagcgcaa     2880

gugaccaagg ugaaaaagua auuccaccag cuggacaaac agaagacgcu gaacccauaa     2940

gugaaccaga aaaaguagaa acaggaucag aacccggaga uacugaacca cuagaguugg     3000

gaggaccagg ggcugagccc gaacaaaaag aacaaucaac aggccagaaa agaccgcuca     3060

aaaacgauga acuauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  4977
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt13)

<400>  4977
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaagaaa cgcaaacaca ggaccaacca auggaagaag      120

aagaaguuga aacauuugcc uuccaagcug aaaucgcuca acuaaugucc cucauaauaa      180

acacauuuua caguaauaag gaaauauucc uacgagaauu aauaucaaau aguagugacg      240

cauuagauaa aauacguuac gaaagccuaa cagauccgag uaaacuagac ucaggaaaag      300

aacuacacau aaacuuaaua ccaaacaaac aagaccgaac acucacaaua guagacacag      360

guauaggcau gacgaaagcc gauuuaauaa acaaccucgg aaccauugca aaaagcggaa      420

ccaaggcauu cauggaagcu cuacaagcag gagcggacau cagcaugaua ggccaguucg      480

gaguggguuu cuauucagca uaccucguag cagaaaaagu aaccgucaua acgaagcaca      540

acgacgauga acaauaugca ugggaaucau ccgccggagg aaguuucaca guccgaacug      600

acacagguga acccauggga agagguacua aaguaauccu ucaucugaaa gaagaucaaa      660

ccgaauaccu cgaagaacga cgaauaaaag aaauuguaaa aaagcauuca caauucaucg      720

gauacccuau aacacucuuc guagaaaaag aaagggauaa agaaguaagc gaugaugaag      780

cagaagaaaa ggaagacaaa gaagaagaaa aagaaaaaga agaaaaagaa ucagaagaua      840

aaccagaaau agaagacgua ggauccgacg aagaagaaga aaaaaaagac ggugacaaaa      900

aaaaaaaaaa aaagauaaaa gaaaaauaca uagaccaaga agaauuaaau aaaaccaaac      960

cgauauggac gagaaauccc gacgacauaa ccaacgaaga auacggagaa uucuauaaaa     1020

gccugaccaa cgacugggaa gaccaucugg cagucaaaca cuucagugua gaaggacaau     1080

uagaauucag agcacuacua uuuguaccga gacgagcacc auucgacuua uucgaaaaua     1140

gaaaaaaaaa aaacaacaua aaauuguacg uaagaagggu cuucauaaug gacaauugug     1200

aagaacuaau acccgaauau cuaaacuuca uuagaggcgu uguagacuca gaagaccuuc     1260

cacucaauau aucaagagaa auguuacaac aaaguaaaau acugaaggua auaaggaaaa     1320

auuuaguaaa aaaaugcuug gaacuauuca cagaacuagc agaagacaaa gaaaacuaca     1380

aaaaauuuua ugaacaauuc ucaaaaaaca uaaaguuagg aauucacgaa gauagccaaa     1440

auagaaagaa acuaucugaa uuguuacgau auuauacauc cgcaucaggu gacgaaaugg     1500

ugucguuaaa agauuacugc acacgaauga aagaaaacca aaaacauaua uauuacauaa     1560

caggagaaac aaaagaucaa guagcaaaca gcgcauucgu cgaacgacug agaaagcacg     1620

gauuagaagu aauauacaug auagaaccaa uagaugaaua uuguguacaa caauuaaaag     1680

aauucgaagg aaaaacucuc guaucaguaa caaaggaagg acuugaacua ccagaagaug     1740

aagaagaaaa aaaaaaacaa gaagaaaaaa agacaaaauu ugaaaaccuc ugcaaaauaa     1800

ugaaagacau acuggaaaaa aaaguagaaa aaguaguagu cucaaacaga cuagugaccu     1860

caccuuguug uauagucaca agcacauaug gauggaccgc aaacauggaa agaauaauga     1920

aagcacaagc auuaagagau aacucaacaa uggguuacau ggcagcuaaa aaacaucucg     1980

aaauaaaucc agaucauucu auaauagaaa cucuuagaca aaaagcagaa gcagauaaaa     2040

acgacaagag uguaaaagac uuagucauac uauuauacga aacggcacua cucagcagug     2100

gauuuaguuu agaagaucca caaacacacg cgaacaggau cuacagaaug auuaaacuag     2160

gauuaggaau cgaugaagau gacccaacag cagacgacac aucagcagca guaacagaag     2220

aaaugccacc acuagaaggg gacgaugaca cuagccgaau ggaagaagua gacuaaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  4978
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt13)

<400>  4978
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucaa aacuagacuc aggaaaagga cuacacauaa      120

accuaguacc aaacaaacaa aaccaaacac uaacaauagu agacacaaga auaggaauga      180

caaaaacaga ccuaauaaac aaccuaggaa caguaacaaa aagcggaaca aaagcauuca      240

uggaagcacu acaagcagac gcagacauaa gcaugauagg acacuucgga guaggauucu      300

acucagcaua ccuaguagca aaaaaaguaa caguaauauc aaaacacaac aacgacgaac      360

aauacacaug ggaaucaagc gcaggaggaa gcuucacagu aagaacagac gaauaaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  4979
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt13)

<400>  4979
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaagaag uacaucaugg agaagaagaa gucgaaacgu      120

uugcuuucca agcggaaaua gcgcaacuaa ugagccuaau aauaaacaca uucuauagua      180

acaaagaaau cuucuugagg gaauuaauuu caaacgccuc cgaugcauua gacaaaauaa      240

gauacgaaag cuuaacagac ccaucaaaau uagauagcgg aaaagagcua aaaaucgaca      300

uaauaccuaa cccacaagaa cguacacuga cacuuguaga uacaggaaua ggaaugacaa      360

aagcagaccu aauaaacaac cuaggaacua uagcuaaauc aggcacgaaa gccuucaugg      420

aagccuuaca agcaggagca gauauaucaa ugauaggaca auuuggagug ggauucuaca      480

gcgcauaccu aguagcagaa aaaguagucg uaauaaccaa acauaaugac gacgaacaau      540

acgcauggga aagcucggca ggaggcagcu uuacaguaag agcagaucau ggcgaaccua      600

uaggaagggg caccaaaguc auccuacauc ucaaagaaga ucaaacagaa uauuuagaag      660

aaagacgagu gaaagaggua gucaaaaagc auucccaauu uauaggcuau ccaauaaccu      720

uauaccuaga aaaagaaaga gaaaaagaaa uaucagacga cgaagccgaa gaagaaaaag      780

gagaaaaaga agaagaagau aaagacgaug aagaaaaacc aaaaauagaa gauguaggaa      840

gcgaugaaga agacgacuca ggaaaagaca aaaaaaaaaa gacaaaaaaa auaaaagaaa      900

aauauaucga ucaagaagaa cucaacaaaa caaaacccau auggacaaga aauccagacg      960

acauaacaca ggaagaauac ggagaauucu auaaaagccu uacgaaugac ugggaagauc     1020

aucuagcagu aaaacacuuc ucuguagaag gacaacuaga auuccgagcc cuacuauuca     1080

uaccaagacg cgcaccauuc gaccuauucg aaaauaaaaa aaaaaaaaac aauauaaaau     1140

uauauguacg gagaguguuc auaauggaca guugcgauga acuaauacca gaauacuuaa     1200

acuuuauaag aggaguggua gacucagaag accuaccccu aaauauaagc cgggagaugu     1260

uacaacaaag caaaauauua aaaguaauca ggaagaacau uguaaaaaaa ugucuggaac     1320

uauuuucaga guuagcagaa gauaaagaaa acuacaaaaa auucuacgaa gcauucucaa     1380

aaaauuuaaa auuagggaua caugaagaca gcacaaacag aagaagacug agcgaacuac     1440

uaagauauca uacaagucaa aguggagacg aaaugacuuc acuaagugaa uacguaucaa     1500

gaaugaaaga aacacaaaaa ucuauuuacu acauaacugg agaaucaaaa gaacagguag     1560

caaacagcgc auuugucgaa cgaguaagaa aacgaggauu cgaaguaguu uauaugacag     1620

aaccuaucga ugaauauugc guccaacaac uaaaagaauu ugacggaaaa ucacuuguca     1680

guguaacaaa agaaggacua gaacugcccg aagacgaaga agaaaaaaaa aaaauggaag     1740

aaucaaaggc uaaauucgaa aaucuaugca aauuaaugaa agaaauacuc gacaaaaaag     1800

uagaaaaagu aaccauaagc aaucgacuag uaucaagucc uugcuguaua gucacaucaa     1860

cauauggaug gacagcgaau auggaaagga uaaugaaagc ccaagcacuu agagacaaua     1920

guacaauggg auacaugaug gccaaaaagc aucuagaaau aaauccugac cacccaaucg     1980

uagaaacacu aagacaaaaa gcagaagcag auaaaaacga caaagcaguu aaagacuuag     2040

uugucuuauu auucgaaaca gcacuacucu caaguggauu cucacuagaa gacccccaaa     2100

cacauaguaa cagaauauac cgaaugauua aauugggauu aggaaucgac gaagacgaag     2160

uggcagccga agaaccaaau gccgcaguac ccgaugaaau accaccccua gaaggagacg     2220

aagacgcaag uagaauggaa gaaguagauu aaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  4980
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt13)

<400>  4980
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agggcauuau ggguucuagg acuauguugc guacuacuaa      120

cguucggauc aguaagagca gacgaugaag uagaugucga uggcacagua gaggaagacc      180

uaggaaaauc aagagaagga agccguacag acgacgaagu agugcaaaga gaagaggaag      240

caauccaguu ggauggacua aaugcaaguc aaauaagaga acuaagagaa aaaucagaaa      300

aauucgcauu ucaagcagaa gugaacagaa ugaugaaacu aauaaucaau ucauuauaua      360

aaaacaaaga aauauuccug agagaacuaa uaagcaacgc aagugaugcu uuagauaaaa      420

uacgacuaau uagcuuaaca gacgaaaaug cauuaagcgg aaaugaagag uuaacaguaa      480

aaauaaaaug ugacaaagaa aaaaacuuac uccaugugac agacacagga guaggaauga      540

cccgcgagga auugguaaaa aaucuaggaa cgauagcuaa aagcggaaca agugaauuuc      600

uuaauaaaau gacagaagca caagaagacg gccaaucaac aagugaacua auaggacaau      660

ucggaguugg uuuuuauagu gcuuuuuuag uugcugacaa aguaauaguc acgucgaaac      720

auaauaacga cacacaacac aucugggaaa gugacucgaa ugaauuuuca guuauagcag      780

auccaagagg aaauacgcua ggcagaggga caacaauaac auuaguacuu aaagaagaag      840

caucagauua uuuagaauua gauacaauaa aaaaccuagu aaaaaaauau agucaauuca      900

uaaauuuccc cauauaugua uggaguagua aaacagaaac gguagaagaa ccaauggaag      960

aagaagaagc agcuaaagaa gaaaaagagg aaagugacga ugaagcagca guugaagaag     1020

aagaagaaga aaaaaagccg aaaacuaaaa aagucgaaaa aacgguaugg gacugggaac     1080

uuaugaacga uauaaagccc auauggcaga gaccgagcaa agaaguagaa gaagaugaau     1140

auaaagcauu uuacaaauca uuuaguaaag aaucagacga uccaauggcu uacauacauu     1200

uuacagccga gggagaagua acauucaaau caauuuuguu uguaccaaca agugcuccca     1260

gagggcuauu cgaugaauac ggaucaaaaa aaagcgacua uauaaaacuc uauguaagaa     1320

gaguauucau caccgacgac uuccacgaua ugaugccuaa auaccuaaau uucguaaaag     1380

gagucguaga uagugaugac uuaccauuaa auguaagcag agaaacucuc caacaacaua     1440

aauuacuaaa agugauacgu aaaaaauuag uaagaaaaac acucgacaug auaaaaaaaa     1500

uagcggauga uaaauauaau gauacauucu ggaaagaauu cggaacaaau auaaaacuug     1560

gcguaauaga agaucacucu aauagaacaa gacuagcaaa acucuuaagg uuccaaagcu     1620

cacaucaccc aaccgauaua acuucauuag aucaauaugu agaaaggaug aaagaaaaac     1680

aagauaaaau auauuuuaug gcaggaucau caagaaaaga agcugaaagu agcccauucg     1740

ucgaaagacu ucuuaaaaaa ggguaugaag uuauauauuu gacagaacca guagaugaau     1800

auuguauaca ggcacuacca gaauucgaug guaaaagauu ccaaaacgua gcaaaagaag     1860

gcguaaaauu cgacgaaagu gagaaaacua aggaaucacg agaagcggua gaaaaagaau     1920

ucgagcccuu acucaauugg augaaagaca aagcacuaaa agauaaaauc gaaaaagcug     1980

uggucaguca aagauuaaca gaaucaccau gcgcauuagu ugcaagucaa uauggguggu     2040

caggaaauau ggaaagaaua augaaagcgc aagcauauca aacuggaaag gauauaucga     2100

cuaacuacua cgcaucgcaa aagaaaacau ucgaaauaaa uccuagacac ccauuaauaa     2160

gagacaugcu acgaagaauc aaagaagaug aagacgacaa gacaguacua gaucuagcag     2220

uaguauuauu ugaaacagca acauuaagau cggguuaccu ucuuccggau acaaaagcau     2280

acggcgacag aauagaaaga augcucagac uaucacucaa caucgaccca gaugcaaaag     2340

uggaagagga accagaagaa gaaccagaag aaacagcaga agauacgaca gaagacacug     2400

aacaagauga ggacgaagaa auggacgugg gaacugacga agaagaagaa acugcaaaag     2460

aaagcacugc ugagaaagau gaacuauaag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  4981
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt13)

<400>  4981
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaagagaac uaagagcucu auuacucugg ggaagaagac      120

uacgaccauu auuaagagcc ccugcauuag cagcuguccc aggcgguaaa ccuauccuau      180

guccaagaag gacgacagcg caauuaggac cuagaagaaa uccagcuugg agcuuacaag      240

cagguagauu auuuaguaca caaacagcag aagauaaaga agaaccucua cauagcauaa      300

ucaguaguac agaaucugua caaggaagua caaguaaaca cgaauuucaa gccgaaacaa      360

agaaacuccu ugacaucgua gcuagaaguc uauauucaga aaaagaagua uucaucaggg      420

aauuaauuuc aaaugcauca gaugccuuag aaaaacuaag acacaaacug guauccgaug      480

gacaagcccu accagaaaug gagauacauu uacaaacaaa cgcagaaaaa gguaccauca      540

caauccagga uacagguaua ggcaugacuc aagaagaacu uguuucuaac cuaggaacua      600

uagcaagauc uggcaguaaa gcauuccuag augcuuuaca aaaccaagca gaagcaucuu      660

caaaaauaau aggacaauuu gguguaggau ucuauagugc auuuauggug gcugaucgug      720

uagaaguuua uucacgguca gcagcuccag gaucauuagg auaccaaugg cuaucugaug      780

guucaggagu cuucgagauu gcagaagcau ccggaguaag aacaggcaca aaaaucauaa      840

uacaccuaaa aucugauugc aaagaauuuu cuagcgaagc aagaguaaga gauguaguca      900

caaaauacuc caacuucguc ucauucccac uauacuuaaa uggcagacga augaauacuc      960

uacaagcuau auggaugaug gauccaaaag auguccggga auggcaacau gaagaguucu     1020

auagauacgu ugcucaagcu cacgacaaac cacgauauac acuucauuac aaaaccgaug     1080

caccacuuaa uauaagauca auauuuuaug uaccagacau gaaaccaucu auguucgaug     1140

uauccagaga auuaggauca ucuguagcau uauacucaag aaaaguguua auacaaacua     1200

aagcaacaga uaucuuacca aaauggcuuc gauucauaag aggaguugua gauucagaag     1260

acaucccacu aaacuuaucg agagaauuac uacaagaauc agcacuuauu agaaaacuaa     1320

gagauguccu acaacaaaga uuaauaaaau ucuuuauaga ucaaucaaag aaagaugcag     1380

aaaaauacgc aaaauucuuc gaagacuaug gacuauuuau gagggaaggc auaguaacug     1440

caacagaaca agaaguuaaa gaagacauug caaaacuacu aagauaugaa aguuccgcgu     1500

uaccuucagg ccaacucacg agucuaagcg aauaugcaag ccgcaugcgu gcaggaacua     1560

gaaacauaua cuaccuaugu gcgccuaaca ggcaucucgc agaacauucc ccuuacuacg     1620

aagcaaugaa aaagaaagau acagaaguac ucuucugcuu cgaacaauuu gaugaacuca     1680

cauuauuaca ucuacgcgag uucgacaaaa agaaauuaau auccguagaa acagacaucg     1740

ucguagacca cuauaaagaa gaaaaauuug aagacagauc ccccgcagca gaauguuuaa     1800

gugaaaaaga aacagaagaa uuaauggcau ggaugagaaa cguacuuggc ucaagaguua     1860

cuaacguuaa aguaacucua cgacuagaca cacauccugc caugguaacg gucuuagaaa     1920

ugggagcagc aagacacuuc cuuagaaugc aacaauuagc aaaaacccaa gaagaaagag     1980

cacaauuacu acaaccaaca uuagaaauca auccuaggca ugcauuaaua aagaaacuaa     2040

accagcuuag agcaagcgaa cccggucuug cacaacuauu aguagaucaa aucuaugaaa     2100

acgccaugau agcagcaggu cuaguugacg accccagagc aaugguaggu agacuuaacg     2160

aacuacucgu caaagcauua gaaaggcauu aaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  4982
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt13)

<400>  4982
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaauau caucacuacc uacacaacua uucaaaugcu      120

gcuucugcga cuuccuaaaa guaaaaaugc acacaauguc auccucacac cuauucuacc      180

uagcacuaug ccuacuaaca uucacaucau cagcaacagc cggaccagaa acacuaugcg      240

gagcagaacu aguagacgca uuacaauucg uaugcggaga cagaggauuc uacuucaaca      300

aaccaacagg auacggauca ucaucaagaa gagcaccaca aacaggaaua guagacgaau      360

gcuguuucag aucaugcgac uuaagaagac uagaaaugua cugcgcacca uuaaaaccag      420

caaaaagcgc aagaucagua agagcacaaa gacauacaga caugccaaaa acacaaaaag      480

aaguacaccu aaaaaacgca ucaagaggau cagcaggaaa caaaaacuac agaauguaag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  4983
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt13)

<400>  4983
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaauaccaa ugggaaaauc aaugcuagua cuauuaacau      120

uucuagccuu cgcaucaugu ugcauagcag cauacagacc aagugaaacu cuauguggag      180

gagaauuagu agauacacua caauuuguau guggagauag agguuucuau uucaguagac      240

cagcaagcag aguaucaaga agaaguagag gaauaguaga agaaugcugu uucagaucau      300

gugaccuagc acuacuagaa acauauugcg caacaccagc aaaaucagaa agagauguau      360

caacaccacc aacaguauua ccagauaacu uuccaagaua cccuguagga aaauuuuucc      420

aauacgauac auggaaacaa ucaacacaaa gacuaagaag aggacuacca gcacuacuaa      480

gagcaagaag aggacacgua cuagcaaaag aacuagaagc auuuagagaa gcaaaaagac      540

auagaccauu aauagcauua ccaacacaag auccagcaca cggaggagca ccaccagaaa      600

uggcaucaaa cagaaaauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  4984
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt13)

<400>  4984
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacucauuuu caacaucagc auucggacca guagcauucu      120

cacuaggauu acuacuagua cuaccagcag cauucccagc cccaguacca cccggagaag      180

acuccaaaga cguagccgcc ccacacagac aaccacuaac aucauccgaa agaauagaua      240

aacaaauaag auacauacua gacggaaucu cagcacuaag aaaagaaaca ugcaacaaau      300

caaacaugug cgaaucauca aaagaagcac uagcagaaaa caauuuaaac cuaccaaaaa      360

uggcagaaaa agacggcugc uuccaaucag gauucaauga agaaaccugc cuaguaaaaa      420

uaauaacagg auuacucgaa uucgaaguau acuuagaaua ccuacaaaac agauucgaau      480

caucagaaga acaagcaaga gcaguacaaa ugagcacaaa aguacucaua caauuccuac      540

aaaaaaaagc aaaaaaucua gacgcaauaa caacaccaga cccaacaaca aacgcaucac      600

uacuaacaaa acuacaagca caaaaccaau ggcuacaaga caugacaacu caccuaauac      660

ucagauccuu caaagaauuu cuacaauccu cacuaagagc acuaagacaa auguaaggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  4985
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt13)

<400>  4985
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccauuacuau gguuaagagg uuuucuauua gcaucaugcu      120

ggauaauagu aagaucaagu ccaacaccag gaagugaagg ucauagugca gcaccugacu      180

guccuaguug cgcauuagca gcauuaccaa aagacguacc aaacagccag ccagaaaugg      240

uagaagcagu aaaaaaacau auauuaaaua ugcuacaucu aaaaaaaagg ccagacguaa      300

cacaaccagu accaaaagcg gcuuuauuaa augcaauaag aaaauuacau guagguaaag      360

uaggagaaaa cgguuacgua gaaauagagg augacauagg ccgaagagca gaaaugaaug      420

aacuaaugga acaaacaagu gaaauaauaa cauuugcaga aucaggaaca gcaagaaaaa      480

cgcuacacuu cgaaauaagc aaagaaggaa gcgaucuuag ugugguagaa agagcagaag      540

uaugguuauu ccugaaggua cccaaagcca aucgaacgag aacaaaagua acaauaagau      600

uauuucaaca acaaaaacau ccacaagguu cacuagauac aggagaggaa gccgaagaag      660

uagguuuaaa aggagaaaga ucugaauuau uauuguccga aaaaguagua gaugccagaa      720

aaaguaccug gcauguauuu ccagugaguu caucaauaca aagauuacua gaucaaggua      780

aaucaucacu agauguaaga auagcaugug aacaauguca agaaagugga gcuaguuuag      840

uacuauuagg aaagaaaaaa aaaaaggagg aagaaggaga aggaaaaaaa aaaggaggag      900

gagaaggagg agcgggagca gaugaagaaa aagaacaaag ucauagacca uucuuaaugu      960

uacaagcaag acaaagcgaa gaucauccac acagaagaag acgacgagga cuagaaugcg     1020

auggaaaagu caauauaugu uguaaaaaac aauuuuuugu aucauuuaaa gacauaggau     1080

ggaacgauug gauaauagcg ccaucaggau aucacgcuaa cuauugugaa ggagaauguc     1140

caagccauau agcaggaacg aguggaagcu cauuaucauu ucacagcacg guaauaaacc     1200

auuauagaau gagaggacau agcccauuug caaauuuaaa aucauguugu guaccuacaa     1260

aacuacgucc aaugagcaug cuauauuacg acgacggaca aaauauuaua aagaaagaua     1320

uccaaaauau gauaguagaa gagugcggau guagcuaagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  4986
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt13)

<400>  4986
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gauggauuac cagggagagc auuaggagca gcaugucuau      120

uauuauuagc agcagguugg uuaggcccag aagcaugggg aucuccaaca ccaccaccaa      180

caccagcagc acccccacca ccaccaccac caggaagucc aggaggaagc caagauacau      240

guacaagcug ugguggauuu agaagaccag aagaauuagg aagaguagau ggagacuuuu      300

uagaagccgu aaaaagacac auacuuucaa gauuacaaau gagaggaagg ccaaauauaa      360

cacaugcagu accaaaggca gcaaugguua cagcauuaag aaaauuacac gcaggaaaag      420

uaagagaaga ugguagagua gaaauaccac auuuagacgg gcacgcauca ccaggugcag      480

augggcaaga aagaguaagu gagauaauua gcuuugcaga aacagaugga uuagcaucau      540

caagaguacg auuauauuuc uuuauaagua acgaaggaaa ucaaaaucua uucguagugc      600

aagcaucacu augguuauau uuaaaauuau ugccauaugu acuagaaaaa ggaagcagaa      660

gaaagguaag aguuaaaguu uauuuucaag aacaagguca uggagaucga uggaauaugg      720

uagaaaaacg aguagauuua aaaagaucag gauggcauac auuuccacua acagaagcaa      780

uacaagcauu auucgaaaga ggcgaaagaa gacugaauuu agacgugcaa ugugacucau      840

gccaagaauu agcagugguu ccagucuuug uagacccagg agaagaaagc cauagaccau      900

uuguaguagu acaagcaaga cuaggagaua guagacauag aauaagaaaa agagguuuag      960

aaugugacgg aagaacaaau uuauguugca gacaacaauu cuuuauugau uuuagguuaa     1020

uagguuggaa ugauuggaua auagcaccaa caggauauua uggaaauuau ugugaaggaa     1080

gcuguccagc auauuuagcu gguguaccag guucagcuag uaguuuucac acagcaguag     1140

ucaaucaaua ucguaugcga ggauuaaauc cugguacugu aaauagcugu uguauaccaa     1200

caaaacuaag uacaauguca auguuauauu uugaugauga auauaauaua guuaaaagag     1260

auguuccaaa uaugauagua gaagaaugug gaugcgcuua aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  4987
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt13)

<400>  4987
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcauuacgag ucuuacuuuu aacagcauua acucugugcc      120

acggauuuaa ucuugauaca gaaaaugcaa ugacauuuca agaaaacgca cgaggauuug      180

gccagucggu aguacaguua caggguagca ggguuguugu cggugcccca caagaaauag      240

uagcagccaa ucaaagaggu ucacuauacc aaugugauua cucuacagga aguugugagc      300

ccauaagauu acaaguaccc gucgaagcag ucaauauguc ccuaggacua aguuuagcag      360

caacaacuag cccaccacaa uuacuagcuu gcggcccaac cguacaccag acauguucug      420

aaaauaccua ugucaaaggu uuaugcuucu uauucgguag uaauuuaaga cagcaaccac      480

aaaaauuucc ugaagcacua cgcggauguc cucaagaaga cuccgacaua gcauuucuaa      540

uagacggaag uggcaguaua auaccccaug acuuuaggag aaugaaagaa uuugugucca      600

caguaaugga acaacuaaag aaaucuaaga cacuuuucuc auuaaugcaa uauagugaag      660

aauuuagaau acauuucacc uucaaagaau uucaaaacaa cccgaaucca agaucccuag      720

uuaaaccaau aacccaguua cuaggaagaa cacauacugc cacaggcauu cgaaaaguag      780

uacgagaacu auuuaacauu acuaauggag cuagaaagaa cgcuuucaaa auucuaguag      840

uuauaacuga uggagagaaa uucggagacc cucuuggaua cgaagauguu auaccagaag      900

ccgauagaga aggagucaua agauauguaa uaggaguagg cgaugccuuc cgaagcgaaa      960

aauccagaca ggaacuaaau acaauagcua gcaaaccacc gagggaccac guuuuucaag     1020

ucaauaauuu ugaagcauua aaaaccauuc aaaaccaacu aagggagaaa auauucgcua     1080

uagaaggaac acaaaccgga ucuaguagua gcuuugaaca ugaaaugucc caagaagguu     1140

uuucugcugc gauaacuuca aauggcccac uacuaucaac agucgguagu uaugauuggg     1200

ccggaggagu auuccuuuau acaaguaaag aaaaaucaac auucauaaau augacaagag     1260

uagacucuga uaugaaugau gccuauuuag gauacgcagc agcaaucaua cuacgcaaca     1320

gaguccaauc acucguacua ggugccccca gauaccaaca uaucggucug gucgcuaugu     1380

uucgucaaaa uacagguaug ugggaaagua augcaaaugu aaaagguacu caaauaggcg     1440

cauauuuugg ugcuucauua ugcagcguug acguggauuc gaacgguagu acagacuuag     1500

uguuaauagg cgcaccccac uacuacgaac aaacaagagg ugggcaggua ucaguaugcc     1560

cucuacccag aggccgugcc agauggcaau gugacgcagu acuauaugga gaacaagggc     1620

aaccaugggg uagauuuggg gcugcauuga caguuuuagg agacguaaau ggagauaaac     1680

uaacggaugu ugcuauagga gccccuggug aggaagauaa uagaggagcg guauaccuau     1740

uucauggaac aucuggaagu ggaauuucac cuagucacuc acaaaggaua gcaggaucca     1800

agcucucccc acgauuacaa uauuuuggac agagccuauc gggaggucaa gaucuaacua     1860

uggaugguuu gguggaucuc accguaggcg cucaagguca ugugcuacua uuacgaucac     1920

aaccuguacu uagaguaaaa gccauaaugg aguucaaccc aagagaagua gcucguaaug     1980

uauucgaaug caacgaucaa guuguaaaag gcaaagaagc aggagaagug cgugucuguc     2040

uucauguuca gaaaagcaca cgugaucgau uaagagaggg ccaaauucaa ucuguaguua     2100

cauacgacuu agccuuagac uccggacgac cacacucucg cgcagucuuu aaugaaacga     2160

aaaacucaac acgaaggcaa acacaaguac uaggauuaac ucaaacaugc gaaacccuua     2220

aacuacaauu accuaacugu aucgaagacc caguaucucc aaucguauug agacuaaauu     2280

uuuccuuagu aggcacacca cuuagugcuu uuggaaaucu aagaccgguc uuagcagaag     2340

augcucaaag auuauuuacc gcacuguucc cauucgagaa aaacugugga aacgauaaua     2400

uaugccaaga cgacuuaucu auuacauucu cauucauguc guuagauugu cuaguaguag     2460

gaggacccag agaauuuaau guaaccguca caguucgaaa ugacggagaa gacucauaua     2520

gaacccaagu aacauucuuc uuuccguuag aucucagcua ucggaaagua ucaacauuac     2580

aaaaccaacg aagccaacga ucauggaggc ucgcauguga aagcgcuucc aguacggaag     2640

uaaguggagc acucaaaucu acaucuugcu cuauuaacca cccaauauuu ccggaaaaca     2700

gugaggucac uuuuaauauc accuucgacg uagauagcaa agccaguuua ggaaauaaac     2760

uucuucucaa ggcaaacgua acuucugaaa auaauaugcc aagaaccaac aaaacagagu     2820

uccaacuaga auuaccaguc aaauacgcag uauauauggu aguaacaagu cauggaguuu     2880

ccacgaaaua ccuaaacuuu acugcaucag aaaacacaag cagaguaaug caacaucaau     2940

accaaguauc aaauuuagga caacgaaguu uaccaauauc guuaguuuuc cuggucccag     3000

ucagauugaa ucaaacagua aucugggaua gaccacaagu aacauuuuca gaaaaucucu     3060

caucaaccug ucauaccaag gaaagauuac cuucacauuc agauuuucua gcagaacuac     3120

gcaaagcucc aguaguuaau ugcucaaucg caguauguca aagaauacaa ugugacaucc     3180

cauucuuugg cauucaagaa gaauuuaacg cuacauuaaa aggaaaucuu aguuuugauu     3240

gguacaucaa aaccagucau aaccauuuac uaauagucuc uacugcugaa auacuauuua     3300

augauucugu auuuacucua uuaccaggac aaggagcuuu uguucgauca caaacagaaa     3360

cuaaaguaga accauucgaa gucccaaauc cauuaccauu aaucgugggu ucuucuguag     3420

gcggcuuauu acuuuuagca uuaauaacug cugccuugua uaaauuagga uuuuucaaaa     3480

ggcaauauaa agauaugaug ucugaaggag guccacccgg agccgaacca caauaaggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  4988
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt13)

<400>  4988
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucccuca aaacacuacc auucuuacua cuacuccaug      120

uacaaauauc caaagcauuc ccuguaucau caaaagaaaa aaacacaaaa acaguacaag      180

acuaccuaga aaaauucuac caauuaccuu caaaccaaua ccaaucaaca agaaaaaacg      240

gaacaaacgu uauaguagaa aaacuaaaag aaaugcaacg uuucuuuggu uuaaauguaa      300

cagguaaacc aaacgaagaa acauuagaca ugaugaaaaa accaagaugu ggaguaccag      360

acuccggcgg auuuauguua acaccaggaa auccaaaaug ggaaagaaca aauuuaacuu      420

accgaauaag aaacuacaca ccucaauuaa gcgaagcaga aguagaaaga gcaauaaaag      480

augccuucga acuauggucc guagcaucac cucuaauuuu cacaagaaua ucacaaggag      540

aagcagacau caacauagcu uuuuaucaaa gagaucacgg agacaauuca ccauuugaug      600

gaccaaacgg aauccuagca caugcauuuc aacccgguca aggaauagga ggagacgcac      660

acuucgaugc cgaagaaaca uggaccaaca cuucagcaaa cuacaaccua uuucuaguag      720

cagcacauga auucggccac ucauuaggac ucgcucauuc cucagacccu ggagcccuaa      780

uguaucccaa cuaugcauuc agagaaacau caaacuauuc acuaccucaa gacgacauag      840

auggaauuca agcuaucuac ggauuaucau caaacccaau ucaaccaaca ggaccaucaa      900

cacccaaacc uugugaccca ucccuaacau uugacgcuau aacaacacua agaggagaaa      960

uauuauucuu caaagacaga uacuuuugga gaagacaccc ucaacuacaa agaguugaaa     1020

ugaacuuuau aucauuauuc uggccaucac uaccaacagg aauacaagca gcauacgaag     1080

acuucgauag agacuuaaua uuccuuuuca aaggaaacca auacugggcc cuaaguggau     1140

acgacauauu acaagguuau ccuaaagaca uaucaaacua cggauuucca ucuucaguac     1200

aagcaauaga cgcagcaguc uucuauagau caaaaacaua cuuuuucgua aacgaccaau     1260

ucuggagaua ugacaaccaa cgacaauuua uggaaccagg auauccaaaa ucaauaucag     1320

gagcauuccc uggaauagaa uccaaaguag acgcaguauu ucaacaagaa cacuucuucc     1380

auguuuuuuc aggaccaaga uacuacgcuu uugacuuaau agcacaaaga guaacaagag     1440

uagcaagagg aaacaaaugg cuaaacugcc gauauggaua aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  4989
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt13)

<400>  4989
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucauuauggc aaccauuagu uuugguacuu uuaguauuag      120

gauguuguuu ugcugcacca cgucaaagac aaaguacauu aguccuauuu ccaggcgauu      180

uaagaacaaa uuuaacagac agacaacuug cagaagaaua ucuauauaga uaugguuaua      240

caagaguagc ugaaaugaga ggugaaucaa aaucucuagg accagcauua uuacuacuac      300

aaaaacaguu aucacuacca gaaaccgggg aacuagacuc agcuacacuu aaagcaauga      360

gaacuccacg guguggaguc ccagaucucg gucgguuuca aacauuugaa ggagaccuua      420

aauggcauca ucacaauaua acauauugga uacagaauua uucagaagac cuaccaagag      480

cgguuauaga cgacgcauuc gcccgagcau uugcacuaug gagugcugua acaccauuga      540

cuuuuacaag gguauauagu cgagaugcag auaucguaau acaauuuggu guagcagagc      600

auggggaugg auacccuuuu gacgguaaag acggacuucu agcacaugca uuuccaccag      660

gaccuggaau acaaggagau gcccauuuug augacgacga acuauggagu cuuggaaaag      720

gagucguagu accuacaaga uuugguaaug cugauggugc agcaugucau uuuccuuuua      780

uauuugaagg acgaucuuac ucugcaugca cuacagaugg acguucagau ggauuaccau      840

gguguucuac uacagccaau uaugauacag augauagauu ugguuuuugu ccuucagaac      900

gauuauauac gcaagaugga aaugcagaug gaaaaccuug ucaauuccca uuuauauuuc      960

aaggacaauc auauucagca uguacaacag auggacgaag cgauggauau cgauggugug     1020

caacaacagc uaacuacgac agagauaaau uauuugguuu uuguccaacu cgcgcugacu     1080

caacagucau gggugguaau agcgcuggug aauuaugugu auuuccauuu acuuuccuug     1140

gcaaagaaua cucaacaugc acaucggaag gaagaggaga uggacgauua uggugugcaa     1200

cuacuaguaa uuucgacagu gacaaaaaau ggggauuuug uccggaccaa ggguauucac     1260

uuuucuuagu ugcagcacac gaauucgguc augcacuugg ccuagaccau ucaucaguac     1320

cugaagcucu uauguaccca auguauagau uuacagaagg accuccacuc cauaaagacg     1380

augucaacgg cauacgccau cuauaugguc cacguccaga gccugaacca aggccuccca     1440

caacaacaac accacaaccu acugcuccac cuacaguaug cccgacuggc ccaccaacag     1500

uacauccauc ugaaagacca acggccggac caacgggacc uccuucagcg gguccaacag     1560

gaccaccaac agcaggcccc agcacugcca cuacaguacc auuaucaccu guggacgaug     1620

cuuguaaugu uaauauauuu gaugcaauag cugaaauugg uaaucaacug uauuuauuua     1680

aagauggaaa auauuggcga uuuagugaag gacgcggauc uagaccccaa ggaccauuuc     1740

uaauugccga uaaauggcca gcccuaccua gaaaauuaga uucuguauuu gaagaaagau     1800

uaucaaaaaa auuauuuuuu uucucaggaa gacaaguaug gguuuauaca ggagcaucag     1860

uacuaggacc uagaagacua gauaaacuag guuuaggagc cgacgucgca caaguuacag     1920

gcgcccuaag aucaggaaga ggaaaaaugu uauuauucag cgguagaaga uuauggagau     1980

uugaugugaa agcacaaaug guugauccaa gaucagcuag cgaagucgau cgaauguucc     2040

cagguguacc auuggauacu caugauguuu uucaauauag agaaaaagca uauuuuuguc     2100

aagauagauu uuauuggcgu guuucaucua ggagugaauu aaaccaagug gaucaaguag     2160

gauauguaac auacgauaua cuacaauguc cagaagauua aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  4990
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt13)

<400>  4990
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacccaggag uauuagcagc auuccucuuc uuaucaugga      120

cacacugccg agcauuacca uuaccaucag gaggagacga agacgaucua ucagaagaag      180

accuucaauu cgcagaaaga uacuuaagau cauacuacca cccaacaaac uuagcaggua      240

uacuaaaaga aaacgcagcc ucuucaauga cagaaagacu uagagaaaug caaucauucu      300

ucggauuaga aguaacagga aaauuagaug acaauacacu agauguaaug aaaaaaccua      360

gaugcggagu uccugacgua ggagaauaua acgucuuucc aagaacauua aaauggucca      420

aaaugaaccu aacauauaga auaguaaacu auacaccaga uaugacccau ucagaagucg      480

aaaaagcauu caaaaaagca uucaaaguau ggucagaugu aacaccucua aacuucacaa      540

gacuacauga cggaauagca gacaucauga uaagcuuugg aauaaaagaa cacggagauu      600

ucuacccauu cgacggacca ucuggauuau uagcccacgc auuuccccca ggaccaaauu      660

auggaggaga cgcacauuuc gaugacgaug aaacauggac aucaucauca aaaggauaca      720

accuauucuu aguagcagca cacgaauucg gacacucuuu aggcuuagac cauucaaaag      780

accccggagc acuaauguuc ccaauauaua cauauacagg aaaaagccac uucauguuac      840

cagacgauga cguccaaggu auacaaaguc uauacggacc aggagaugaa gauccuaacc      900

caaaacaucc aaaaacccca gacaaaugug auccaucauu aucauuagau gccauaacau      960

cauuacgagg agaaacaaug auuuucaaag accguuucuu cuggcgucuu cacccacaac     1020

aagucgacgc agaacucuuu uuaacaaaau cguuuuggcc ugaacuacca aacagaauag     1080

augcagcaua cgaacacccu agucacgacu uaauauuuau uuuucgagga cgaaaauucu     1140

gggcccuaaa uggauacgau auauuagaag gauacccuaa aaaaauaucu gaacuaggau     1200

uaccaaaaga aguaaaaaaa auaucagccg caguccacuu ugaagauaca ggaaaaacac     1260

uucuauuuuc aggcaaucaa gucuggagau acgacgacac aaaccacaua auggacaaag     1320

acuaccccag auuaauagaa gaagacuucc caggcauagg ugacaaagua gacgcaguau     1380

acgaaaaaaa cggauauaua uauuucuuca acggaccaau acaauuugaa uacucuauau     1440

ggucaaacag aauaguaaga guaaugccag caaacuccau uuuauggugc uaaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  4991
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt13)

<400>  4991
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacaccaa acacaacaga agacuacgau acaaccacag      120

aauuugauua uggagacgca acaccauguc aaaaaguaaa cgaaagagcc uuuggcgcgc      180

aacuacuacc cccauuauac ucacuagucu ucgucauagg acuaguaggu aauauacuag      240

uaguacuagu auuaguccaa uacaaaagau uaaaaaauau gacaucaaua uauuuacuaa      300

acuuagcaau aucagauuua cuauuccuau ucacauuacc auucuggauc gacuacaaac      360

uaaaagacga cuggguauuu ggagacgcaa ugugcaaaau acucucagga uucuacuaca      420

caggccuaua cucugaaauc uucuucauaa uacuacuaac aauagauaga uaccuagcaa      480

uaguucaugc aguauucgca uuaagagcca gaaccgucac auucggaguc auaacaucaa      540

uaauaauaug ggccuuagca auauuagcau caaugccagg acuauacuuu ucuaaaacac      600

aaugggaauu cacacaucau acaugcucac uucacuuccc ucacgaaucc cuaagagaau      660

ggaaacucuu ccaagcauua aaacucaauc uuuucggacu aguacuaccc cuacucguaa      720

ugaucauaug cuacacagga auaauaaaaa uacuacuacg acgaccaaac gaaaaaaaau      780

caaaagcagu aagauuaaua uucguaauaa ugaucaucuu cuuccuuuuu uggaccccuu      840

acaaccucac aauacuaaua ucaguauucc aagacuuuuu auucacacac gaaugugaac      900

aauccagaca ucucgacuua gcaguacaag ucaccgaagu aauagcauac acacacuguu      960

gcguuaaccc cguaauauac gcuuuuguag gagaaagauu ccgaaaauau cuaagacaac     1020

uauuucacag acgaguugca guacacuuag ucaaaugguu accauuucua ucaguagaua     1080

gauuagaaag agucucaucc acaucaccau caaccggaga acacgaauua ucagcaggau     1140

ucuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  4992
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt13)

<400>  4992
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agaacacuag caugccuacu auuacuagga ugcggauacc      120

uagcacaugu acuagcugaa gaagcagaaa uaccaagaga aguaauagaa agacuagcaa      180

gaucacaaau acacucaaua agagaccuac aacgacuacu agaaauagac ucagucggaa      240

gugaagacuc acucgacaca agucuaagag cacacggagu acacgcaaca aaacacguac      300

cagaaaaaag accacuaccc auaagaagaa aaagaagcau agaagaagca guaccagcag      360

uaugcaaaac acgaacagua auauacgaaa uaccaagauc acaaguagac ccaacaucag      420

caaacuuccu aauauggccc ccaugcguag aaguaaaaag augcacagga ugcugcaaca      480

caucaagcgu aaaaugccaa ccaagcaggg uacaccacag aagcgucaaa guagcaaaag      540

uagaauacgu aagaaaaaaa ccaaaacuaa aagaaguaca aguaagacua gaagaacacc      600

uagaaugcgc augugcaaca acaagccuaa auccagauua cagagaagaa gacacaggaa      660

gaccaagaga aagcggaaaa aaaagaaaaa gaaaaagacu aaaaccaaca uaaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  4993
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt13)

<400>  4993
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagaugcu gggcauuauu cuuaucauua ugcuguuacc      120

uaagauuagu aucagcagaa ggagauccaa uaccagaaga acuauacgaa augcuaagcg      180

aucacaguau aagaagcuuu gacgaucuac aaagauuacu ucacggcgau ccaggagaag      240

aagacggagc agaauuagac cuaaauauga caagaucaca cucaggagga gaauuagaau      300

cacuagcacg uggaagaaga agccuaggaa gucuaacaau agcagaaccu gcaaugauag      360

cagaauguaa aacacgaaca gaaguauucg aaauaucaag aagauuaaua gauagaacaa      420

augcaaauuu cuuaguaugg ccaccaugug uagaaguaca aagaugcagu ggaugcugca      480

auaacagaaa cguacaaugu agaccaacac aaguacaauu aagaccagua caaguaagaa      540

aaauagaaau aguaagaaaa aaaccaauau uuaaaaaagc aacagucaca uuagaggacc      600

accucgcaug caaaugugaa accguagcag cagcaagacc aguaacaaga agcccaggcg      660

gaagccaaga acaaagagca aaaacaccac aaacuagagu uacaauaaga acaguaagag      720

uacgaaggcc cccaaaagga aaacauagaa aauucaaaca cacacacgac aaaacagcac      780

uaaaagaaac acuaggagcg uaaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  4994
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt13)

<400>  4994
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucauuauuug gauuauuacu acuuacauca gcauuagcag      120

gacaaagaca agguacacaa gcagaaagca aucuaucaag caaauuccaa uuuucaucca      180

auaaagaaca aaauggagua caagacccac aacacgaaag aauaauaacc gucagcacaa      240

acggcucaau acauagucca cgauucccac auacauaucc aagaaacacc guacucgucu      300

ggagauuagu agcaguugaa gaaaauguau ggauccaauu aacauucgac gaaagauuug      360

gauuagaaga cccugaagac gacauaugca aauacgacuu uguagaagua gaagaaccau      420

cagacggaac aauauuagga cgauggugcg gaucagguac aguaccuggu aaacaaaucu      480

caaaaggcaa ccaaauaaga auaagauucg uaagcgauga auacuuccca agugaaccag      540

gauucuguau acauuacaau aucgucaugc cacaauucac agaagcagua ucaccaucag      600

uacuaccacc aucagcucua ccauuagacu uacuaaauaa cgcuauaaca gcauuuucaa      660

cauuagaaga cuuaauacga uacuuagaac cagaaagaug gcaacuagac cuagaagacc      720

uauacaggcc aacauggcaa cuucuaggaa aagcauuugu auuuggaaga aaaucacgag      780

uugucgaucu aaaccuauua acagaagaag uaagacuuua cucaugcaca ccaagaaacu      840

uuucaguauc cauaagagaa gaacuaaaaa gaacagauac aauauucugg ccaggaugcc      900

uacuaguaaa aagaugcggc ggaaauugcg caugcugcuu acacaacugu aacgaaugcc      960

aaugcguacc aucaaaaguu acaaaaaaau accacgaagu acuacaauua agacccaaaa     1020

cuggaguuag aggacuacau aaaucucuaa cagacguagc acuagaacau cacgaagaau     1080

gugacugcgu uugccgagga agcacaggag gcuaaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  4995
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt13)

<400>  4995
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagauuaa uauuuguaua cacacuaaua ugugcaaacu      120

ucugcucaug cagagacaca uccgcaacuc cacaaucagc aucaauaaaa gcuuuaagaa      180

acgcaaaucu aagaagagac gaucuauaca gaagagacga aaccauacaa guaaaaggaa      240

acggcuacgu acaaagccca cgauucccua acucauaccc aagaaaucua uuauuaacau      300

ggcgacuaca cucccaagaa aacacaagaa uacaacuagu auucgauaac caauucggau      360

uagaagaagc agaaaacgac auauguagau augauuucgu agaaguagaa gacauaucag      420

aaacaucaac uauaauacga ggaagauggu gcggacacaa agaaguacca ccacgaauaa      480

aaucaagaac aaaccaaaua aaaauaacuu ucaaaucaga ugacuacuuc guugcaaaac      540

ccggauucaa aauauauuau agccuacuag aagacuucca accagcagca gcuucagaaa      600

caaauuggga aucagucaca agcucaauau caggaguauc auauaauagc ccaucaguua      660

cagacccaac acuaaucgcc gacgcauuag acaaaaaaau agcagaauuc gauacaguag      720

aagaucuacu aaaauacuuu aacccugaau cauggcaaga agaucuagaa aacauguauc      780

uagacacacc cagauacaga ggaagaagcu accacgacag aaaaucaaaa guagacuuag      840

acagacuaaa ugaugacgca aaaagauacu caugcacacc aagaaacuac agcguaaaua      900

uaagagaaga acuaaaauua gcaaacguag uauucuuccc aagaugucua uuaguacaac      960

gcugcggagg aaacugugga ugcggaacag uaaacuggcg aagcuguaca ugcaauuccg     1020

gaaaaacagu caaaaaauac cacgaaguac uacaauucga acccggacau auaaaaagaa     1080

gagguagagc aaaaacaaug gcacuaguag auauacaauu agaccaccau gaaagaugcg     1140

auuguauaug cagcucuaga ccuccaagau aaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  4996
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt13)

<400>  4996
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccauu caaaauuccc agcagcagga augucaagac      120

cauuagacac aucauuacga uuaaaaacau ucucaucaaa aucagaauac caacuaguag      180

uaaaugcagu aagaaaacua caagaaucag gauucuauug gucagcagua acaggaggag      240

aagcaaauuu auuacuauca gcagaaccag caggaacuuu ccuaauacga gacucaucag      300

accaacgaca cuucuuuacu cuaucaguaa aaacacaauc aggaacaaaa aaccucagaa      360

uacaauguga aggaggauca uucucccuac aaucagaccc cagaucaaca caacccguac      420

caagauucga cugcguacua aaacuaguac accacuacau gccaccaccc ggagcaccau      480

ccuucccauc uccaccaaca gaaccaucau cugaaguacc ugaacaacca ucagcacaac      540

cacuaccugg aucaccacca agaagagcau acuacauaua cucaggagga gaaaaaauac      600

cacuaguacu uucaagacca cuaucaucua auguagcaac acuacaacac uuaugccgaa      660

aaacaguaaa cggccaccua gacucauacg aaaaagucac acaacuacca ggaccaauaa      720

gagaauucuu agaucaauac gacgcaccac uauaaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  4997
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt13)

<400>  4997
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaccaucag caggacaauu agcauuauuu gcacuaggaa      120

uaguacuagc agcaugucaa gcauuagaaa acucaacauc accacuauca gcagacccac      180

caguagcagc agcaguagua ucacauuuua augauugccc agacucacac acacaauucu      240

gcuuucacgg aacauguaga uuucuaguac aagaagacaa accagcaugu guaugucauu      300

caggauaugu aggagcaaga ugugaacaug cagauuuauu agcaguagua gcagcaucac      360

aaaaaaaaca agcaauaacu gcauuaguag uaguaaguau aguagcauua gcaguauuaa      420

uaauaacaug uguauuaaua cauugcuguc aaguaagaaa acauugugaa uggugcagag      480

cauuaauaug uagacaugaa aaaccuucag cauuacuaaa aggaagaaca gcaugcuguc      540

acucagaaac aguaguauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  4998
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt13)

<400>  4998
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaccaucag gucuacgacu acuaccucuc uuacuaccuu      120

uacuauggcu ccucguacua accccaggcc gaccagcagc uggccuauca acaugcaaaa      180

caauagacau ggaauuaguc aaaagaaaaa gaauagaagc aauuagagga caaauacuau      240

caaaauuaag auuagccucc ccaccuucuc aaggagaagu accaccaggu ccacuaccug      300

aagcaguccu agcacuauac aacucaacaa gagacagagu agcaggagaa uccgcagaac      360

cagaacccga accagaagca gacuauuaug caaaagaagu caccagagua cuaaugguag      420

aaacacauaa ugaaaucuac gauaaauuua aacaaucaac acauucaaua uacauguuuu      480

ucaacacaag ugaacuaaga gaagcaguac cagaaccagu auuacuauca cgagccgaau      540

uaagacuccu aagacuuaaa cuaaaaguag aacaacacgu ugaauuauac caaaaauacu      600

cuaacaacuc auggagauac uuaucuaauc gacuacuagc acccucagac ucaccagaau      660

ggcucucauu cgacguaacc ggaguaguac gacaauggcu aucccguggc ggugaaauag      720

aaggauucag acuauccgca cacugcucuu gcgacucaag agacaauaca uuacaaguag      780

auauaaacgg auucacaaca ggaagaagag gagacuuagc uacaauccac ggaaugaacc      840

gccccuuccu acuauuaaug gcaacuccuc uagaaagagc acaacacuua caauccucaa      900

gacacagaag agcacuagac acaaacuauu guuucucaag cacugaaaaa aacugcugcg      960

uccgacaauu auacauagac uuccgaaaag aucucggaug gaaauggaua cacgaaccaa     1020

aaggauacca cgccaacuuc ugccucgguc cauguccaua uaucugguca cuagauacac     1080

aauacuccaa aguacuagca uuauauaacc aacauaaucc aggagcauca gcagcgccau     1140

gcugcguacc acaagcauua gaaccacucc caauaguaua cuaugucgga agaaaaccaa     1200

aaguagaaca acuaucaaac augauaguca gaucaugcaa auguucuuaa ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  4999
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt13)

<400>  4999
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuauugcg uacuuucagc auuucuaaua uuacaccuag      120

uaacagucgc uuuaaguuua agcacaugcu caaccuuaga cauggaccaa uuuaugagaa      180

aacgaauaga agcaauaaga ggacaaauau uauccaaacu aaaacuaaca ucaccacccg      240

aagauuaucc agaaccagaa gaagucccac cagaaguaau aucaauauau aacagcacaa      300

gagaccuccu acaagaaaaa gcaucaagaa gagcagcagc augcgaacga gaaagaucag      360

augaagaaua uuacgcuaaa gaaguauaca aaauagacau gccccccuuc uuuccaucag      420

aaaaugcaau accaccaacc uuuuacagac ccuauuuucg aauaguaaga uucgauguau      480

cagccaugga aaaaaacgca ucaaaccuag ucaaagcgga auucagagua uuccgacuuc      540

aaaacccaaa agcuagaguu cccgaacaac gaaucgaacu auaucaaaua cuaaaaucaa      600

aagaccuaac cucacccaca caaagauaca uagacucaaa aguaguaaaa accagagcag      660

agggcgaaug guuaucauuc gacguaacag acgcaguaca cgaauggcua caucacaaag      720

accgaaaucu cggauucaaa auaucacuac acugcccaug cugcacauuc gucccaucaa      780

acaacuauau aauaccaaau aaaucagaag aacuugaagc aagauuugcu ggaauagacg      840

gaacaaguac auacaccucu ggagaccaaa aaacuauaaa aucaacaaga aaaaaaaacu      900

cuggcaaaac accucaccua cuauuaaugc uacuacccuc auacagacua gaaucacaac      960

aaacaaaccg aagaaaaaaa agagcacuag acgcagcaua cuguuucaga aacguacaag     1020

auaacugcug ccucagacca cuauauauag acuucaaaag agaccuagga uggaaaugga     1080

uacaugaacc aaaaggcuac aacgccaacu ucugcgcagg agcaugccca uacuuauggu     1140

caucugacac acagcacuca agaguacuau cacuauacaa cacaauaaau ccagaagcuu     1200

cagcaagucc cugcugcgua ucacaagacu uagaacccuu aacuauauua uauuauaucg     1260

gaaaaacacc aaaaauagaa caacuaucaa acaugauagu aaaaucaugu aaauguaguu     1320

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  5000
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt13)

<400>  5000
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaugcacc uccaaagagc ccucgucguu cucgcacuac      120

uaaacuucgc aaccguauca cuaucccuau caacaugcac aacccuagac uucggacaca      180

uaaaaaaaaa aagaguagaa gcaauccgag gccaaauuuu aucaaaacua agacuaacau      240

caccaccaga acccacaguc augacacacg uaccauacca aguccuagca cuauacaacu      300

caacacgaga acuauuagaa gaaaugcacg gagaaagaga agaaggaugu acacaagaaa      360

acacugaaag ugaauacuau gcaaaagaaa uacacaaauu cgauaugaua caaggacuag      420

cagaacacaa cgaacuagca guaugcccaa aaggaauaac aucaaaagua uuucgauuca      480

acguaucauc aguagagaaa aaucgaacaa accuauuuag agccgaauuu agaguccuaa      540

gaguccccaa uccaucauca aaaagaaacg aacaacgcau agaacuauuu caaauacuac      600

gcccagacga acacauagca aaacaaagau acauaggugg aaaaaaccuc ccaaccagag      660

gaacagccga auggcuauca uucgacguaa cagacaccgu cagagaaugg cuacuccgca      720

gagaaucaaa cuuaggucua gaaauaucaa uacacugccc augccauaca uuucaaccaa      780

auggagacau auuagaaaac auacaugaag uaauggaaau caaauucaaa ggaguagaca      840

acgaagacga ccacggacga ggcgaccucg gcagacuaaa aaaacaaaaa gaucaccaca      900

auccacaccu aauccuaaug augauacccc cccacagacu agacaaccca ggacaaggag      960

gacaacgaaa aaaaagagca cucgacacaa auuauuguuu ccgaaaucua gaagaaaacu     1020

gcugcguccg uccacuuuac auagacuuca gacaagaccu aggauggaaa uggguucacg     1080

aaccaaaagg auauuaugcc aacuucugcu caggacccug cccauacuua agaucagcag     1140

acacaacaca cucuacagua cuaggacuau acaacacacu aaacccagaa gccucagcau     1200

cacccugcug ugucccacaa gaccuagaac cuuuaaccau acuauacuac guaggaagaa     1260

cuccuaaagu agaacaacuu ucaaauaugg uaguaaaauc augcaaaugc ucauaaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  5001
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt13)

<400>  5001
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaccaguag caguaugggc agcacuugca guaggacucg      120

aauuaugggc agcagcacau gcauuaccug cacaaguugc auucacaccc uacgcacccg      180

aaccaggcuc aaccuguaga uuaagagaau auuacgauca aacagcucaa augugcuguu      240

cuaaaugcuc accuggccaa caugcaaaag uauuuugcac uaaaacaucu gauaccguau      300

gugauucuug ugaagacuca acauauacac aacuauggaa cuggguucca gaaugucuau      360

caugcggauc aagauguuca ucagaccaag uugaaacaca agcauguacu cgugaacaaa      420

aucgaauuug cacauguaga ccaggauggu auugcgcuuu aucgaaacaa gaaggaugua      480

gacuaugcgc accucuuaga aaaugcagac caggcuuugg agucgcucga cccggaacug      540

aaacaucaga cguaguaugc aaaccuugug caccagguac auucucuaac acaacaaguu      600

caacagauau uuguagacca caccaaauau guaacguagu ugcuauacca ggaaacgcau      660

cuauggaugc aguauguaca ucuacgucac cuaccagauc aauggcacca ggagcaguuc      720

acuuaccaca accaguauca acaagaaguc aacacacaca accaacaccu gaacccucaa      780

cugcaccaag cacuucauuu cuacuaccaa ugggucccuc accaccugcu gaaggaucaa      840

caggagacuu cgcauuaccu gucggacuua ucguaggagu uacagcauua ggacuauuaa      900

uaaucggugu aguaaauugu guuauuauga cacaaguaaa aaaaaaaccc uuauguuuac      960

aaagagaagc caaaguaccu cauuuaccag cagauaaagc cagaggaacc caagguccag     1020

aacaacaaca uuuauuaauc acagcucccu caucaucauc aucaucuuua gaaucaucag     1080

caagugcucu agauagaaga gcucccacaa gaaaccaacc ucaagcacca ggugucgaag     1140

caucaggagc uggugaagcu cgugcuucua cgggaucuuc agauucauca cccggaggac     1200

acggaacaca aguaaaugua acaugcauag uaaaugucug uuccaguucg gaucauucau     1260

cacaauguuc aucacaagca ucaucuacua ugggagauac agauaguuca ccaucagaau     1320

ccccaaaaga cgaacaagua ccauuuucaa aagaagaaug cgcauuuaga ucacaauuag     1380

aaacaccaga aacauuauua ggaucaacug aagaaaaacc acuaccacua ggcguaccag     1440

augcaggaau gaaacccuca uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  5002
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt13)

<400>  5002
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaguaauga gauuauuucc auguuucuua caauuauuag      120

caggauuagc auuaccagca guaccaccac aacaaugggc guuaucagca ggaaauggaa      180

guagugaagu agaaguagua ccauuucaag aaguaugggg aagaucauau uguagagcac      240

uagaaagacu aguagaugua guaagugaau auccaagcga aguagaacau auguuuucac      300

caucaugugu aaguuuauua agauguacgg gaugcugugg agaugaaaau uuacauugug      360

uaccaguaga aacagcaaau guaacaaugc aauuauuaaa aauaagaagu ggagauagac      420

caucauaugu agaauuaaca uuuagccaac auguaagaug ugaauguaga ccauuaagag      480

aaaaaaugaa accagaaaga agaagaccaa aaggaagagg aaaaagaaga agagaaaaac      540

aaagaccaac agauugucau uuauguggag augcaguacc aagaagauaa ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  5003
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt13)

<400>  5003
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagauagac aaacagauac agcgccaagu ccaucauacc      120

auuuauuacc aggaagaaga agaacaguag augcagcagc gaguagagga caaggaccag      180

agccagcacc aggaggagga guagaaggag uuggagcaag aggaguagcg cuaaaauuau      240

uuguacaacu auuaggaugc aguagauucg guggagcagu aguaagagcu ggagaagcag      300

aaccauccgg ugcagccaga agcgcaagua guggaagaga agaaccacaa ccagaagaag      360

gagaagaaga agaagaaaaa gaagaggaaa gaggaccaca auggagacuu ggcgcuagaa      420

aaccugggag cuggacagga gaagcagcug uaugcgcaga uagugcacca gcagcaagag      480

caccacaagc auuagcaaga gcaucaggac gaggaggaag aguagcaaga aggggagccg      540

aagaaagugg accuccacau aguccaagua gaagaggauc agcaaguaga gcugggccag      600

gaagggcauc ugaaacaaug aauuuuuuau uaaguugggu acauuggagu uuagcuuuau      660

ugcuauauuu acaucacgca aaauggaguc aagcagcacc aauggcagaa ggagggggac      720

aaaaucauca cgaaguagua aaauuuaugg auguuuauca aaggaguuau ugucauccua      780

uagaaacguu aguagauaua uuucaagaau acccagauga aauagaguau auauuuaaac      840

cgaguugugu accauuaaug agauguggag gauguuguaa ugacgaagga cuagaaugug      900

uaccaacaga agaaagcaau auaacuaugc agauaaugag aauaaaaccu caucaaggac      960

aacauauagg agaaaugagu uuuuugcaac acaauaagug cgaauguaga ccaaaaaaag     1020

aucgagcaag acaagaaaaa aaaagcguaa gagguaaagg uaaaggacaa aaaagaaaaa     1080

gaaaaaaaag uagauauaaa agcuggagug uauacguagg ggcaagaugu uguuugaugc     1140

cauggagccu cccaggaccu cauccgugug gaccauguuc agagagaaga aaacaucugu     1200

uuguacaaga uccacaaaca uguaaaugca guugcaaaaa uacggauuca agauguaaag     1260

cgagacaauu agaauuaaau gaaaggacau guagaugcga uaagccgaga agauaaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  5004
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt13)

<400>  5004
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuucuuac uaucaugggu acauuggagc uuagcacuau      120

uacuauaccu acaccacgca aaauggucac aagcagcacc aauggcagaa ggaggaggac      180

aaaaccacca ugaaguagua aaauucaugg auguauacca aagaucauac ugccacccaa      240

uagaaacacu aguagacaua uuccaagaau acccagacga aauagaauac auauucaaac      300

caucaugugu accauuaaug agaugcggag gaugcugcaa cgacgaagga cuagaaugug      360

uaccaacaga agaaaguaac auaacaaugc aaauaaugag aauaaaacca caucaaggac      420

aacacauagg agaaaugagc uuccuacaac acaauaaaug cgaaugcaga ccaaaaaaag      480

acagagcaag acaagaaaaa aaaaguguaa gaggaaaagg aaaaggacaa aaaagaaaaa      540

gaaaaaaauc aagauacaaa ucauggucag uauacguagg agcaagaugc ugccuaaugc      600

cauggucacu accaggacca cacccaugcg gaccaugcuc agaaagaaga aaacaccuau      660

ucguacaaga cccacaaacc ugcaaaugca guugcaaaaa cacagacagc agaugcaaag      720

caagacaauu agaacuaaac gaaagaacau gcagaugcga uaaaccacga agauaaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  5005
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt13)

<400>  5005
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaccacuau uaagaagauu auuacuagca gcauuacuac      120

aauuagcacc cgcacaagca ccuguaucac aaccagaugc accaggacau caaagaaaag      180

uaguaucaug gauagacgua uacacaagag caacauguca accaagagaa guaguaguac      240

cauuaacagu agaacuaaug ggaacagucg caaaacaacu aguaccauca ugcguaacag      300

uacaaagaug cggaggcugu uguccagacg auggauuaga auguguucca acaggacaac      360

aucaaguaag aaugcaaaua cuaaugauaa gauacccauc aucucaacua ggagaaaugu      420

ccuuagaaga acauagucaa ugcgaaugca gaccaaaaaa aaaagauuca gcaguaaaac      480

cagaccgagc agcaacacca caucauagac cacaaccacg aucaguacca ggcugggacu      540

cagccccagg agcaccauca ccagcagaua uaacccaucc cacaccugca ccaggaccau      600

cugcacaugc agcaccuuca acaacaucag cauuaacacc aggaccagca gcagcagccg      660

cagacgcagc ugcaucauca guagcaaaag gaggagcaua aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  5006
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt13)

<400>  5006
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccucuuag gauucuucuc aguagcuugc ucauuauuag      120

ccgccgccuu auuaccagga ccaagagaag caccagcagc agccgcagca uuugaaucag      180

gauuagacuu aagugaugcu gaaccagacg caggagaagc uacagcauau gccaguaaag      240

acuuagaaga acaauuaaga ucaguaaguu ccguagacga auuaaugaca guacucuauc      300

cagaauacug gaaaauguau aaaugucaac uaagaaaagg cggauggcaa cauaauaggg      360

aacaagcaaa ucuaaauuca agaacagaag aaacuauaaa auucgcagcc gcacacuaua      420

acacggaaau acuaaaaagu auagauaacg aauggagaaa aacacaaugc augccaagag      480

aaguaugcau agauguagga aaagaauuug gaguagcaac aaacacauuu uucaaaccac      540

cauguguaag cguauacaga uguggcgguu gcugcaauag cgaaggauua caauguauga      600

acacuagcac uucauacuua ucaaaaacac uauuugaaau uacaguacca uuaagucaag      660

gaccuaaacc aguaacgaua aguuuugcaa accacacauc auguagaugu augucaaaac      720

uagauguaua uagacaagua cacucaauaa uaagaagauc acuaccagca acacuuccac      780

aaugccaagc agcaaauaaa acauguccaa caaacuauau guggaacaac cacauaugca      840

gaugucuagc acaagaagau uucauguuua guucagacgc aggagacgac agcacagaug      900

gauuucauga cauaugcgga cccaacaaag aauuagacga agaaacuugu caaugcguau      960

guagagcagg acuacgacca gcaucaugug gaccacauaa agaauuagac agaaacaguu     1020

gccaaugcgu augcaaaaau aaacuauucc caucacaaug uggagcaaau cgagaauuug     1080

augaaaacac augucaaugu guaugcaaaa gaacaugccc aagaaaucaa ccauuaaauc     1140

cagguaaaug cgcaugugaa uguacagaau caccacaaaa augccuauua aaaggaaaga     1200

aauuucacca ucaaacaugc aguuguuaua gaagaccaug uacaaauaga caaaaagccu     1260

gugaaccagg auucuccuac ucagaagaag uauguagaug uguaccaagu uacuggaaaa     1320

gaccacaaau gucauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  5007
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt13)

<400>  5007
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uaccgagaau ggguaguagu aaacguauuc augaugcuuu      120

acguacaacu aguacaagga ucaucaaaug aacacggacc aguaaaaaga ucaagccaau      180

caacauuaga aagaucagaa caacaaauac gagcagcauc aucacucgaa gaacuccuaa      240

gaauaacaca cuccgaagac uggaaacuau ggcgaugcag acuaagauua aaaucauuca      300

caucaaugga uucacgcucc gcaucccaca gaucaacaag auuugccgcc acauuuuacg      360

acauagaaac auuaaaaguc aucgacgaag aauggcaacg aacacaaugc ucaccuagag      420

aaacaugcgu agaaguagca ucagaacuag guaaauccac aaauaccuuu uuuaaaccac      480

cuugcguaaa cguauucaga ugcggaggcu guugcaacga agaaucacua auuuguauga      540

acacaucuac auccuacaua ucaaaacaac uauucgaaau aucaguacca cuaacaagcg      600

uacccgaacu aguccccgua aaaguagcaa accacacagg augcaaaugc cuaccaacag      660

caccaagaca uccauacucc auaauacgaa gaucaauaca aauaccagaa gaagacagau      720

gcucacacuc aaaaaaacua ugcccuauag auaugcuaug ggacagcaac aaaugcaaau      780

gcguacuaca agaagaaaac ccucuagcag gaaccgaaga ccacagccau cuacaagaac      840

cagcauuaug cgguccacau augauguucg acgaagacag augcgaaugc guaugcaaaa      900

caccaugccc caaagaccuu auacaacacc cuaaaaacug uagcugcuuu gaaugcaaag      960

aaucacuaga aacaugcugc caaaaacaca aauuauuuca cccagacaca ugcucaugcg     1020

aagacagaug cccauuccac accagaccau gcgcauccgg uaaaacagca ugugcaaaac     1080

acugcagauu ccccaaagaa aaaagagcag cccaaggacc acacucaaga aaaaauccau     1140

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  5008
<211>  978
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design4 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt1)

<400>  5008
gggucccgca gucggcgucc agcggcucug cuuguucgug ugugugucgu ugcaggccuu       60

auucaagcuu accaugggca ccuggauccu guucgccugc cuccuggggg ccgcguucgc      120

caugccccug ccgccccacc ccggccaccc cggguacauc aacuucagcu acgaggugcu      180

caccccgcug aagugguacc aguccauccg cccgcccuac cccagcuacg gcuacgagcc      240

caugggcggg uggcugcacc accagaucau ccccguccuc ucccagcagc acccgcccac      300

gcacacccug cagccgcacc accacauccc cguggugccc gcccagcagc ccgucauccc      360

ccagcagccc augaugcccg ugcccggcca gcacagcaug accccgaucc agcaccacca      420

gcccaaccug cccccgccgg cccagcagcc cuaccagccc cagcccgugc agccccagcc      480

ccaccagccc augcagccgc agccgcccgu ccaccccaug cagccgcucc cgccccagcc      540

cccgcugccg cccauguucc ccaugcagcc ccugccgccc augcuccccg accugacccu      600

ggaggccugg cccuccacgg acaagaccaa gcgggaggag guggacugag gacuagugca      660

ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug aagaucaaua      720

gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc uaaaaaacau      780

aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga      840

accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      960

uucagagcca ccagaauu                                                    978


<210>  5009
<211>  609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design4 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt1)

<400>  5009
gggucccgca gucggcgucc agcggcucug cuuguucgug ugugugucgu ugcaggccuu       60

auucaagcuu accauggccg ugauggcccc gcggacccug guccuccugc ugagcggcgc      120

gcucgcccug acccagacgu gggccaugcc ccugccgccc caccccggcc accccgggua      180

caucaacuuc agcuacgagg ugcucacccc gcugaagugg uaccagucca uccgcccgcc      240

cuaccccagc uacggcuacg agcccauggg cgggugguga ggacuagugc aucacauuua      300

aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau agcuuauuca      360

ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu      420

uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc      480

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      600

accagaauu                                                              609


<210>  5010
<211>  642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design4 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt1)

<400>  5010
gggucccgca gucggcgucc agcggcucug cuuguucgug ugugugucgu ugcaggccuu       60

auucaagcuu accauggccg ugauggcccc gcggacccug guccuccugc ugagcggcgc      120

gcucgcccug acccagacgu gggccaugcc ccugccgccc caccccggcc accccgggua      180

caucaacuuc agcuacgagg ugcucacccc gcugaagugg uaccagucca uccgcccgcc      240

gcccaugcuc cccgaccuga cccuggaggc cuggcccucc acggacaaga ccaagcggga      300

ggagguggac ugaggacuag ugcaucacau uuaaaagcau cucagccuac caugagaaua      360

agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa      420

gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu uucucugugc      480

uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      600

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                         642


<210>  5011
<211>  972
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design4 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMEL (opt1)

<400>  5011
gggucccgca gucggcgucc agcggcucug cuuguucgug ugugugucgu ugcaggccuu       60

auucaagcuu accaugggca ccuggauccu guucgccugc cuccuggggg ccgcguucag      120

caugccccug ccgccccacc ccggccaccc cggguacauc aacuucuccu acgaggugcu      180

caccccgcug aagugguacc agaacaugau ccgccacccc uacacgagcu acggcuacga      240

gcccaugggc ggguggcugc accaccagau cauccccguc gugucccagc agaccccgca      300

gagccacgcc cuccagcccc accaccacau ccccauggug cccgcccagc agccgggcau      360

cccccagcag cccaugaugc cccugccggg gcagcacucc augaccccca cccagcacca      420

ccagcccaac cugccccucc cggcccagca gcccuuccag ccccagcccg uccagccgca      480

gccccaccag ccccugcagc cccagagccc gaugcacccc auccagcccc ugcucccgca      540

gccgccccug cccccgaugu ucuccaugca gagccugcuc cccgaccugc cccuggaggc      600

cuggcccgcg acggacaaga ccaagcggga ggagguggac ugaggacuag ugcaucacau      660

uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc aauagcuuau      720

ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu      780

cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga aagaaccuag      840

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      960

gccaccagaa uu                                                          972


<210>  5012
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design4 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt1)

<400>  5012
gggucccgca gucggcgucc agcggcucug cuuguucgug ugugugucgu ugcaggccuu       60

auucaagcuu accauggccg ugauggcccc gcggacccug guccuccugc ugagcggcgc      120

gcucgcccug acccagacgu gggccaugcc ccugccgccc caccccggcc accccgggua      180

caucaacuuc uccuacgagg ugcucacccc gcugaagugg uaccagaaca ugauccgcca      240

ccccuacacg agcuacggcu acgagcccau gggcgggugg ugaggacuag ugcaucacau      300

uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc aauagcuuau      360

ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu      420

cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga aagaaccuag      480

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      600

gccaccagaa uu                                                          612


<210>  5013
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design4 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt1)

<400>  5013
gggucccgca gucggcgucc agcggcucug cuuguucgug ugugugucgu ugcaggccuu       60

auucaagcuu accauggccg ugauggcccc gcggacccug guccuccugc ugagcggcgc      120

gcucgcccug acccagacgu gggccaugcc ccugccgccc caccccggcc accccgggua      180

caucaacuuc uccuacgagg ugcucacccc gcugaagugg uaccagaaca ugauccgcca      240

ccccagccug cuccccgacc ugccccugga ggccuggccc gcgacggaca agaccaagcg      300

ggaggaggug gacugaggac uagugcauca cauuuaaaag caucucagcc uaccaugaga      360

auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu      420

aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug      480

ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc      600

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                      645


<210>  5014
<211>  42
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5-UTR of human ribosomal protein Large 32 lacking the 5 terminal 
       oligopyrimidine tract

<400>  5014
ggcgctgcct acggaggtgg cagccatctc cttctcggca tc                          42


<210>  5015
<211>  42
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5-UTR of human ribosomal protein Large 32 lacking the 5 terminal 
       oligopyrimidine tract mRNA

<400>  5015
ggcgcugccu acggaggugg cagccaucuc cuucucggca uc                          42


<210>  5016
<211>  75
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5-UTR of human mitochondrial ATP synthase subunit alpha lacking 
       the 5 terminal oligopyrimidine tract

<400>  5016
gcggctcggc cattttgtcc cagtcagtcc ggaggctgcg gctgcagaag taccgcctgc       60

ggagtaactg caaag                                                        75


<210>  5017
<211>  75
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5-UTR of human mitochondrial ATP synthase subunit alpha lacking 
       the 5 terminal oligopyrimidine tract mRNA

<400>  5017
gcggcucggc cauuuugucc cagucagucc ggaggcugcg gcugcagaag uaccgccugc       60

ggaguaacug caaag                                                        75


<210>  5018
<211>  62
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  5-UTR of human peroxisomal multifunctional enzyme type 2 lacking 
       the 5 terminal oligopyrimidine tract

<400>  5018
gtcccgcagt cggcgtccag cggctctgct tgttcgtgtg tgtgtcgttg caggccttat       60

tc                                                                      62


<210>  5019
<211>  62
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  5-UTR of human peroxisomal multifunctional enzyme type 2 lacking 
       the 5 terminal oligopyrimidine tract mRNA

<400>  5019
gucccgcagu cggcguccag cggcucugcu uguucgugug ugugucguug caggccuuau       60

uc                                                                      62


<210>  5020
<211>  110
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3-UTR of Homo sapiens hemoglobin, alpha 1 (HBA1)

<400>  5020
gctggagcct cggtggccat gcttcttgcc ccttgggcct ccccccagcc cctcctcccc       60

ttcctgcacc cgtacccccg tggtctttga ataaagtctg agtgggcggc                 110


<210>  5021
<211>  110
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3-UTR of Homo sapiens hemoglobin, alpha 1 (HBA1) mRNA

<400>  5021
gcuggagccu cgguggccau gcuucuugcc ccuugggccu ccccccagcc ccuccucccc       60

uuccugcacc cguacccccg uggucuuuga auaaagucug agugggcggc                 110


<210>  5022
<211>  108
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3-UTR of Homo sapiens hemoglobin, alpha 2 (HBA2)

<400>  5022
gctggagcct cggtagccgt tcctcctgcc cgctgggcct cccaacgggc cctcctcccc       60

tccttgcacc ggcccttcct ggtctttgaa taaagtctga gtgggcag                   108


<210>  5023
<211>  108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3-UTR of Homo sapiens hemoglobin, alpha 2 (HBA2) mRNA

<400>  5023
gcuggagccu cgguagccgu uccuccugcc cgcugggccu cccaacgggc ccuccucccc       60

uccuugcacc ggcccuuccu ggucuuugaa uaaagucuga gugggcag                   108


<210>  5024
<211>  132
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3-UTR of Homo sapiens hemoglobin, beta (HBB)

<400>  5024
gctcgctttc ttgctgtcca atttctatta aaggttcctt tgttccctaa gtccaactac       60

taaactgggg gatattatga agggccttga gcatctggat tctgcctaat aaaaaacatt      120

tattttcatt gc                                                          132


<210>  5025
<211>  132
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3-UTR of Homo sapiens hemoglobin, beta (HBB) mRNA

<400>  5025
gcucgcuuuc uugcugucca auuucuauua aagguuccuu uguucccuaa guccaacuac       60

uaaacugggg gauauuauga agggccuuga gcaucuggau ucugccuaau aaaaaacauu      120

uauuuucauu gc                                                          132


<210>  5026
<211>  44
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Center, alpha-complex-binding portion of the 3UTR of an 
       alpha-globin gene (muag)

<400>  5026
gcccgatggg cctcccaacg ggccctcctc ccctccttgc accg                        44


<210>  5027
<211>  44
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Center, alpha-complex-binding portion of the 3UTR of an 
       alpha-globin gene (muag) mRNA

<400>  5027
gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accg                        44


<210>  5028
<211>  186
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3-UTR of human albumin

<400>  5028
catcacattt aaaagcatct cagcctacca tgagaataag agaaagaaaa tgaagatcaa       60

aagcttattc atctgttttt ctttttcgtt ggtgtaaagc caacaccctg tctaaaaaac      120

ataaatttct ttaatcattt tgcctctttt ctctgtgctt caattaataa aaaatggaaa      180

gaatct                                                                 186


<210>  5029
<211>  186
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3-UTR of human albumin mRNA

<400>  5029
caucacauuu aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa       60

aagcuuauuc aucuguuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac      120

auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa      180

gaaucu                                                                 186


<210>  5030
<211>  186
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3-UTR albumin7

<400>  5030
catcacattt aaaagcatct cagcctacca tgagaataag agaaagaaaa tgaagatcaa       60

tagcttattc atctcttttt ctttttcgtt ggtgtaaagc caacaccctg tctaaaaaac      120

ataaatttct ttaatcattt tgcctctttt ctctgtgctt caattaataa aaaatggaaa      180

gaacct                                                                 186


<210>  5031
<211>  186
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3-UTR albumin7 mRNA

<400>  5031
caucacauuu aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa       60

uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac      120

auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa      180

gaaccu                                                                 186


<210>  5032
<211>  187
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3-UTR ALB7

<400>  5032
gcatcacatt taaaagcatc tcagcctacc atgagaataa gagaaagaaa atgaagatca       60

atagcttatt catctctttt tctttttcgt tggtgtaaag ccaacaccct gtctaaaaaa      120

cataaatttc tttaatcatt ttgcctcttt tctctgtgct tcaattaata aaaaatggaa      180

agaacct                                                                187


<210>  5033
<211>  187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3-UTR ALB7 mRNA

<400>  5033
gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa augaagauca       60

auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa      120

cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa      180

agaaccu                                                                187


<210>  5034
<211>  24
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  histone stem-loop sequence

<400>  5034
caaaggctct tttcagagcc acca                                              24


<210>  5035
<211>  24
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  histone stem-loop sequence mRNA

<400>  5035
caaaggcucu uuucagagcc acca                                              24


<210>  5036
<211>  13
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  Kozak

<400>  5036
gccgccacca tgg                                                          13


<210>  5037
<211>  13
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  Kozak mRNA

<400>  5037
gccgccacca ugg                                                          13


<210>  5038
<211>  21
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5038

Met Asp Ala Met Lys Arg Gly Leu Cys Cys Val Leu Leu Leu Cys Gly 
1               5                   10                  15      


Ala Val Phe Val Ser 
            20      


<210>  5039
<211>  22
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5039

Met Asp Ala Met Lys Arg Gly Leu Cys Cys Val Leu Leu Leu Cys Gly 
1               5                   10                  15      


Ala Val Phe Val Ser Pro 
            20          


<210>  5040
<211>  18
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5040

Met Asp Trp Thr Trp Ile Leu Phe Leu Val Ala Ala Ala Thr Arg Val 
1               5                   10                  15      


His Ser 
        


<210>  5041
<211>  24
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5041

Met Pro Met Gly Ser Leu Gln Pro Leu Ala Thr Leu Tyr Leu Leu Gly 
1               5                   10                  15      


Met Leu Val Ala Ser Cys Leu Gly 
            20                  


<210>  5042
<211>  20
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5042

Met Tyr Arg Met Gln Leu Leu Ser Cys Ile Ala Leu Ser Leu Ala Leu 
1               5                   10                  15      


Val Thr Asn Ser 
            20  


<210>  5043
<211>  18
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5043

Met Ala Phe Leu Trp Leu Leu Ser Cys Trp Ala Leu Leu Gly Thr Thr 
1               5                   10                  15      


Phe Gly 
        


<210>  5044
<211>  19
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5044

Met Glu Phe Gly Leu Ser Trp Val Phe Leu Val Ala Leu Phe Arg Gly 
1               5                   10                  15      


Val Gln Cys 
            


<210>  5045
<211>  19
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5045

Met Asp Trp Thr Trp Arg Val Phe Cys Leu Leu Ala Val Thr Pro Gly 
1               5                   10                  15      


Ala His Pro 
            


<210>  5046
<211>  19
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5046

Met Ala Trp Ser Pro Leu Phe Leu Thr Leu Ile Thr His Cys Ala Gly 
1               5                   10                  15      


Ser Trp Ala 
            


<210>  5047
<211>  17
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5047

Met Gly Val Lys Val Leu Phe Ala Leu Ile Cys Ile Ala Val Ala Glu 
1               5                   10                  15      


Ala 
    


<210>  5048
<211>  21
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5048

Met Glu Thr Asp Thr Leu Leu Leu Trp Val Leu Leu Leu Trp Val Pro 
1               5                   10                  15      


Gly Ser Thr Gly Asp 
            20      


<210>  5049
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5049
auggaugcaa ugaagagagg gcucugcugu gugcugcugc uguguggagc agucuucguu       60

ucg                                                                     63


<210>  5050
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5050
auggaugcaa ugaagagagg gcucugcugu gugcugcugc uguguggagc agucuucguu       60

ucgccc                                                                  66


<210>  5051
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5051
auggacugga ccuggauccu guuccucgug gccgccgcga cccgcgucca cagc             54


<210>  5052
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5052
augcccaugg ggucucugca accgcuggcc accuuguacc ugcuggggau gcuggucgcu       60

uccugccucg ga                                                           72


<210>  5053
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5053
auguacagga ugcaacuccu gucuugcauu gcacuaaguc uugcacuugu cacaaacagu       60


<210>  5054
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5054
auggcuuucc ucuggcuccu cuccugcugg gcccuccugg guaccaccuu cggc             54


<210>  5055
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5055
auggaguuug ggcugagcug gguuuuccuc guugcucuuu uuagaggugu ccagugu          57


<210>  5056
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5056
auggacugga ccuggagggu cuucuguuug cuggcuguaa cuccaggcgc ccacccc          57


<210>  5057
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5057
auggccuggu ccccucucuu ccucacccuc aucacucacu gugcaggguc cugggcc          57


<210>  5058
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5058
augggaguca aaguucuguu ugcccugauc ugcaucgcug uggccgaggc c                51


<210>  5059
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5059
auggagacag acacacuccu gcuaugggug cugcugcucu ggguuccagg uuccacaggu       60

gac                                                                     63


<210>  5060
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5060
auggacgcca ugaagcgcgg ccugugcugc gugcuccugc ugugcggggc cgucuucgug       60

agc                                                                     63


<210>  5061
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5061
auggacgcca ugaagcgcgg ccugugcugc gugcuccugc ugugcggggc cgucuucgug       60

agcccc                                                                  66


<210>  5062
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5062
auggacugga ccuggauccu guuccucgug gccgccgcga cccgcgucca cagc             54


<210>  5063
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5063
augcccaugg gcagccugca gccgcucgcc acccuguacc ugcucgggau gcugguggcc       60

uccugccugg gc                                                           72


<210>  5064
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5064
auguaccgga ugcagcugcu cagcugcauc gcccugucgc uggcgcucgu gaccaacagc       60


<210>  5065
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5065
auggccuucc uguggcuccu gagcugcugg gcccugcucg gcaccaccuu cggg             54


<210>  5066
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5066
auggaguucg gccugagcug gguguuccuc gucgcccugu uccgcggggu gcagugc          57


<210>  5067
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5067
auggacugga ccuggcgcgu guucugccug cucgccguca cccccggcgc ccacccg          57


<210>  5068
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5068
auggccugga gcccccuguu ccucacccug aucacccacu gcgccggcuc cugggcg          57


<210>  5069
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5069
augggcguga agguccuguu cgcccucauc ugcaucgccg uggcggaggc c                51


<210>  5070
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5070
auggagaccg acacccugcu ccugugggug cugcuccugu ggguccccgg cagcacgggg       60

gac                                                                     63


<210>  5071
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5071
auggacgcca ugaagcgcgg ccucugcugc guccuccucc ucugcggcgc cgucuucguc       60

ucc                                                                     63


<210>  5072
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5072
auggacgcca ugaagcgcgg ccucugcugc guccuccucc ucugcggcgc cgucuucguc       60

uccccc                                                                  66


<210>  5073
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5073
auggacugga ccuggauccu cuuccucguc gccgccgcca cccgcgucca cucc             54


<210>  5074
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5074
augcccaugg gcucccucca gccccucgcc acccucuacc uccucggcau gcucgucgcc       60

uccugccucg gc                                                           72


<210>  5075
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5075
auguaccgca ugcagcuccu cuccugcauc gcccucuccc ucgcccucgu caccaacucc       60


<210>  5076
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5076
auggccuucc ucuggcuccu cuccugcugg gcccuccucg gcaccaccuu cggc             54


<210>  5077
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5077
auggaguucg gccucuccug ggucuuccuc gucgcccucu uccgcggcgu ccagugc          57


<210>  5078
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5078
auggacugga ccuggcgcgu cuucugccuc cucgccguca cccccggcgc ccacccc          57


<210>  5079
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5079
auggccuggu ccccccucuu ccucacccuc aucacccacu gcgccggcuc cugggcc          57


<210>  5080
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5080
augggcguca agguccucuu cgcccucauc ugcaucgccg ucgccgaggc c                51


<210>  5081
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5081
auggagaccg acacccuccu ccucuggguc cuccuccucu ggguccccgg cuccaccggc       60

gac                                                                     63


<210>  5082
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5082
auggacgcca ugaagagagg ccugugcugu gugcuccuuc ugugcggggc ugucuucguu       60

agc                                                                     63


<210>  5083
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5083
auggacgcca ugaagagagg ccugugcugu gugcuccuuc ugugcggggc ugucuucguu       60

agcccc                                                                  66


<210>  5084
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5084
auggacugga ccuggauccu guuccucgug gccgcugcaa caagagucca cagc             54


<210>  5085
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5085
augcccaugg gcagccugca gccucucgcc acccuuuacc uguuggggau guuaguggcu       60

uccugccugg ga                                                           72


<210>  5086
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5086
auguacagaa ugcagcugcu cagcugcauc gcccuuuccc uggcuuuggu gaccaacucu       60


<210>  5087
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5087
auggccuucc uguggcuccu uagcugcugg gcucuguugg gcaccacauu uggg             54


<210>  5088
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5088
auggaguucg gccugagcug gguguuucuc gucgcccuuu ucagaggggu ucagugc          57


<210>  5089
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5089
auggacugga ccuggagagu guucugccug cucgccguca cacccggcgc ucacccu          57


<210>  5090
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5090
auggccugga gcccccuguu ccucacccuu aucacacacu gcgcuggcuc cugggca          57


<210>  5091
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5091
augggcguga agguccuguu cgcccucauc ugcauugcug uugcagaggc c                51


<210>  5092
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5092
auggagaccg acacacugcu ccuuugggug cuguuguuau ggguccccgg cagcacuggg       60

gau                                                                     63


<210>  5093
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5093
auggacgcca ugaagagagg ccugugcugc gugcugcugc ugugcggcgc cguguucgug       60

agc                                                                     63


<210>  5094
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5094
auggacgcca ugaagagagg ccugugcugc gugcugcugc ugugcggcgc cguguucgug       60

agcccc                                                                  66


<210>  5095
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5095
auggacugga ccuggauccu guuccuggug gccgccgcca ccagagugca cagc             54


<210>  5096
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5096
augcccaugg gcagccugca gccccuggcc acccuguacc ugcugggcau gcugguggcc       60

agcugccugg gc                                                           72


<210>  5097
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5097
auguacagaa ugcagcugcu gagcugcauc gcccugagcc uggcccuggu gaccaacagc       60


<210>  5098
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5098
auggccuucc uguggcugcu gagcugcugg gcccugcugg gcaccaccuu cggc             54


<210>  5099
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5099
auggaguucg gccugagcug gguguuccug guggcccugu ucagaggcgu gcagugc          57


<210>  5100
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5100
auggacugga ccuggagagu guucugccug cuggccguga cccccggcgc ccacccc          57


<210>  5101
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5101
auggccugga gcccccuguu ccugacccug aucacccacu gcgccggcag cugggcc          57


<210>  5102
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5102
augggcguga aggugcuguu cgcccugauc ugcaucgccg uggccgaggc c                51


<210>  5103
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5103
auggagaccg acacccugcu gcugugggug cugcugcugu gggugcccgg cagcaccggc       60

gac                                                                     63


<210>  5104
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5104
auggacgcca ugaagagagg ccugugcugu gugcuccugc uuugcggggc ugucuucguu       60

agc                                                                     63


<210>  5105
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5105
auggacgcca ugaagagagg ccugugcugu gugcuccugc uuugcggggc ugucuucguu       60

agcccc                                                                  66


<210>  5106
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5106
auggacugga ccuggauccu guuccucgug gccgcugcca caagagucca cagc             54


<210>  5107
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5107
augcccaugg gcagccugca gccucucgcc acccuguacc uucuggggau gcucguggcu       60

uccugccugg ga                                                           72


<210>  5108
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5108
auguacagaa ugcagcugcu cagcugcauc gcccuguccc uugcucuggu gaccaacucu       60


<210>  5109
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5109
auggcuuucc uguggcuccu gagcugcugg gcccuucugg gcaccacauu uggg             54


<210>  5110
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5110
auggaguucg gccugagcug gguguuucuc gucgcccugu ucagaggggu ucagugc          57


<210>  5111
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5111
auggacugga ccuggagagu guucugccug cucgccguca cacccggcgc ucacccu          57


<210>  5112
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5112
auggccugga gcccccuguu ccucacccug aucacacacu gcgcuggcuc cugggcc          57


<210>  5113
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5113
augggcguga agguccuguu cgcccucauc ugcauugcug uugccgaggc g                51


<210>  5114
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5114
auggagaccg acacacugcu ccugugggug cuucugcucu ggguccccgg cagcacgggg       60

gau                                                                     63


<210>  5115
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5115
auggaugcga ugaagagagg guuauguugu guguuauugu uauguggagc gguauuugua       60

agu                                                                     63


<210>  5116
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5116
auggaugcaa ugaaaagagg auuauguugu guauuauuau uauguggagc aguauuugua       60

agucca                                                                  66


<210>  5117
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5117
auggacugga cauggauauu auuuuuagua gcagcagcaa caagaguaca uuca             54


<210>  5118
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5118
augccuaugg guucacuuca accuuuagcu acacuuuauc uuuuagguau gcuuguagcu       60

ucauguuuag gu                                                           72


<210>  5119
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5119
auguaccgua ugcaacuacu uucauguaua gcucuaucuc uagcucuagu uacaaauuca       60


<210>  5120
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5120
auggcuuuuu uaugguuauu aucuuguugg gcuuuauuag guacuacuuu uggu             54


<210>  5121
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5121
auggaauuug guuuaucuug gguuuuuuua guugcuuuau uuagaggugu ucagugu          57


<210>  5122
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5122
auggauugga cuuggcgugu auuuuguuua uuagcuguaa cuccaggugc acaucca          57


<210>  5123
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5123
auggccugga guccauuauu uuuaacauua auaacucauu gugcaggcuc augggca          57


<210>  5124
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5124
augggaguaa aaguacuauu ugcauuaaua uguauagcag uagcagaagc a                51


<210>  5125
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5125
auggaaacag auacauuauu auuauggguu uuauuauuau ggguaccugg aaguacaggu       60

gac                                                                     63


<210>  5126
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5126
auggacgcca ugaagagggg ccugugcugu gugcuccugu ugugcggggc agucuucgug       60

agc                                                                     63


<210>  5127
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5127
auggacgcca ugaagagggg ccugugcugu gugcuccugu ugugcggggc agucuucgug       60

agcccc                                                                  66


<210>  5128
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5128
auggacugga ccuggauccu guuccucgug gccgcagcca cuagggucca cagc             54


<210>  5129
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5129
augcccaugg gcagccugca gccacucgcc acccuguacu ugcuggggau gcucguggca       60

uccugccugg gu                                                           72


<210>  5130
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5130
auguacagga ugcagcugcu cagcugcauc gcccuguccu uggcacuggu gaccaacagu       60


<210>  5131
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5131
auggccuucc uguggcuccu gagcugcugg gcauugcugg gcaccacuuu uggg             54


<210>  5132
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5132
auggaguucg ggcugagcug gguguuucuc gucgcccugu ucaggggcgu gcagugc          57


<210>  5133
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5133
auggacugga ccuggagggu guucugccug cucgccguca cucccggcgc acaccca          57


<210>  5134
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5134
auggccugga gcccccuguu ccucacccug aucacucacu gcgcaggcuc cugggcc          57


<210>  5135
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5135
augggcguga agguccuguu cgcccucauc ugcauugcag uggccgaggc g                51


<210>  5136
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5136
auggagaccg acacucugcu ccugugggug uugcugcucu ggguccccgg cagcaccggg       60

gau                                                                     63


<210>  5137
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5137
auggaugcga ugaagagggg guuguguugu guguuguugu uguguggggc gguguuugug       60

agu                                                                     63


<210>  5138
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5138
auggacgcga ugaagagagg gcucuguugc gugcuauugc ucuguggcgc ggucuuuguc       60

ucgccc                                                                  66


<210>  5139
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5139
auggacugga cguggauacu cuuucucgua gccgcggcca cgcgcgugca cuca             54


<210>  5140
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5140
augcccaugg gcucacucca accccuagcc acccucuacc uccucggcau gcucgucgcc       60

ucaugccucg gc                                                           72


<210>  5141
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5141
auguaccgca ugcaauuacu cuccugcauc gcccuauccc ucgcccuagu caccaacucc       60


<210>  5142
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5142
auggccuucc uuuggcucuu auccugcugg gcucuccucg gcaccaccuu cggc             54


<210>  5143
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5143
auggaguucg ggcucucaug gguguucuug gucgcacucu uucgcggggu ccagugc          57


<210>  5144
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5144
auggacugga ccuggcgcgu auucugccua cuagccguaa cccccggcgc ccaccca          57


<210>  5145
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5145
auggccuggu ccccacucuu ccucacacuc aucacccacu gcgccggcuc cugggcc          57


<210>  5146
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5146
auggggguga aggugcuguu ugcguugaua uguauagcgg uggcggaggc g                51


<210>  5147
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5147
auggaaaccg acacacuccu acucuggguc cuccuccucu ggguccccgg cuccaccggc       60

gac                                                                     63


<210>  5148
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5148
auggaugcga ugaagagggg guuguguugu guguuguugu uguguggggc gguguuugug       60

agu                                                                     63


<210>  5149
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5149
auggacgcca ugaaacgagg ccucugcugc guccuacucc ucugcggcgc cguauucguc       60

uccccc                                                                  66


<210>  5150
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5150
auggacugga ccuggauacu cuuucucguc gccgccgcca cccgcgucca cuca             54


<210>  5151
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5151
augcccaugg gcucccucca accccuagcc acacucuacc uccucggcau gcucgucgcc       60

uccugccuag gc                                                           72


<210>  5152
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5152
auguaccgca ugcaacuccu auccugcauc gcccucucac ucgcccucgu aaccaacucc       60


<210>  5153
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5153
auggccuucc ucuggcuccu cucauguugg gcccuacucg gcaccaccuu cgga             54


<210>  5154
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5154
auggaguucg ggcucucgug gguguucuug gucgcgcucu uucgcggggu ccagugc          57


<210>  5155
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5155
auggacugga ccuggcgcgu auucugccuc cuagccguaa cccccggcgc ccaccca          57


<210>  5156
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5156
auggccuggu ccccacucuu ccucacacuc aucacccacu gcgccggcuc cugggcc          57


<210>  5157
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5157
auggggguga aggugcuguu ugcguugaua uguauagcgg uggcggaggc g                51


<210>  5158
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5158
auggaaaccg acacacuccu acucuggguc cuccuccucu ggguccccgg cuccaccggc       60

gac                                                                     63


<210>  5159
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5159
auggacgcga ugaagcgcgg gcucuguugc gugcucuugc ucuguggcgc ggucuuuguc       60

ucg                                                                     63


<210>  5160
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5160
auggaugcga ugaagagggg guuguguugu guguuguugu uguguggggc gguguuugug       60

aguccg                                                                  66


<210>  5161
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5161
auggauugga cguggauacu cuuucucgug gccgcggcca cgcgcgugca cucg             54


<210>  5162
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5162
augcccaugg gcucccucca accccucgcc acccucuacc uccucggcau gcucgucgcc       60

uccugccucg gc                                                           72


<210>  5163
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5163
auguaccgca ugcaacuccu cuccugcauc gcccucuccc ucgcccucgu caccaacucc       60


<210>  5164
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5164
auggccuucc ucuggcuccu cuccugcugg gcccuccucg gcaccaccuu cggc             54


<210>  5165
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5165
auggaguucg ggcucucgug gguguucuug gucgcgcucu uucgcggggu ccagugc          57


<210>  5166
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5166
auggacugga ccuggcgcgu guucugucuc uuggccguga ccccgggcgc gcacccg          57


<210>  5167
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5167
auggccuggu ccccacucuu ccucacacuc aucacccacu gcgccggcuc cugggcc          57


<210>  5168
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5168
augggcguga aagugcucuu ugccuugauc uguaucgcgg ucgcggaagc g                51


<210>  5169
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5169
auggaaaccg acacacuccu acucuggguc cuccuccucu ggguccccgg cuccaccggc       60

gac                                                                     63


<210>  5170
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5170
auggaugcga ugaagagagg guuauguugu guguuauugu uauguggagc gguauuugua       60

agu                                                                     63


<210>  5171
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5171
auggaugcaa ugaaaagagg auuauguugu guauuauuau uauguggagc aguauuugua       60

agucca                                                                  66


<210>  5172
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5172
auggacugga cauggauauu auuuuuagua gcagcagcaa caagaguaca uuca             54


<210>  5173
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5173
augccuaugg guucacuuca accuuuagcu acacuuuauc uuuuagguau gcuuguagcu       60

ucauguuuag gu                                                           72


<210>  5174
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5174
auguacagaa ugcaacuacu aucaugcaua gcacuaucac uagcucuagu aacaaacuca       60


<210>  5175
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5175
auggcauuuu uaugguuauu aucauguugg gcuuuauuag gaacuacauu ugga             54


<210>  5176
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5176
auggaauuug gauuaaguug gguauuuuua guugcauuau uuagaggagu ucagugu          57


<210>  5177
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5177
auggacugga cauggagagu auuuuguuua uuagcaguaa caccaggagc acaucca          57


<210>  5178
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5178
auggccugga guccauuauu uuuaacauua auaacucauu gugcaggcuc augggca          57


<210>  5179
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5179
augggaguaa aaguacuauu ugcauuaaua uguauagcag uagcagaagc a                51


<210>  5180
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5180
auggaaacag auacauuauu auuaugggua uuauuauuau ggguaccagg aaguacagga       60

gac                                                                     63


<210>  5181
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5181
auggaugcua ugaagagagg uuuauguugu guuuuauugu uauguggagc uguauuugua       60

agu                                                                     63


<210>  5182
<211>  66
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__AAA61213.1__signal peptide-HsPLAT

<400>  5182
auggaugcaa ugaaaagagg auuauguugu guauuauuau uauguggagc aguauuugua       60

agucca                                                                  66


<210>  5183
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__AAB59424.1__signal peptide-IgE

<400>  5183
auggacugga cauggauauu auuuuuagua gcagcagcaa caagaguaca uuca             54


<210>  5184
<211>  72
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_055022.2__signal peptide-HsCD5

<400>  5184
augccuaugg guucacuuca accuuuagcu acacuuuauc uuuuagguau gcuuguagcu       60

ucauguuuag gu                                                           72


<210>  5185
<211>  60
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_000577.2__signal peptide-HsIL2

<400>  5185
auguacagaa ugcaacuacu aucaugcaua gcacuaucac uagcucuagu aacaaacuca       60


<210>  5186
<211>  54
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__NP_001020371.3 __signal peptide-HsCTRB2

<400>  5186
auggcuuuuu uaugguuauu aucuuguugg gcuuuauuag guacuacuuu uggu             54


<210>  5187
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__BAC87457.1__signal peptide-immunoglobulin (IgG heavy 
       chain)

<400>  5187
auggaauuug gauuaaguug gguauuuuua guugcauuau uuagaggagu ucagugu          57


<210>  5188
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__AAA52897.1__signal peptide-human immunoglobulin heavy 
       chain

<400>  5188
auggacugga cauggagagu auuuuguuua uuagcaguaa caccaggagc acaucca          57


<210>  5189
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Homo 
       sapiens__AAA59018.1__signal peptide-human immunoglobulin light 
       chain

<400>  5189
auggccugga guccauuauu uuuaacauua auaacucauu gugcaggcuc augggca          57


<210>  5190
<211>  51
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Gaussia 
       princeps__AAG54095.1__signal peptide-GpLuc

<400>  5190
augggaguaa aaguacuauu ugcauuaaua uguauagcag uagcagaagc a                51


<210>  5191
<211>  63
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Mus 
       musculus__BAR42292.1__signal peptide-MmIgkappa

<400>  5191
auggaaacag auacauuauu auuaugggua uuauuauuau ggguaccagg aaguacagga       60

gac                                                                     63


<210>  5192
<211>  1008
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5192

Ile Ala Asn Thr Asn Ser Glu Lys Tyr Asp Phe Glu Tyr Leu Asn Gly 
1               5                   10                  15      


Leu Ser Tyr Thr Glu Leu Thr Asn Leu Ile Lys Asn Ile Lys Trp Asn 
            20                  25                  30          


Gln Ile Asn Gly Leu Phe Asn Tyr Ser Thr Gly Ser Gln Lys Phe Phe 
        35                  40                  45              


Gly Asp Lys Asn Arg Val Gln Ala Ile Ile Asn Ala Leu Gln Glu Ser 
    50                  55                  60                  


Gly Arg Thr Tyr Thr Ala Asn Asp Met Lys Gly Ile Glu Thr Phe Thr 
65                  70                  75                  80  


Glu Val Leu Arg Ala Gly Phe Tyr Leu Gly Tyr Tyr Asn Asp Gly Leu 
                85                  90                  95      


Ser Tyr Leu Asn Asp Arg Asn Phe Gln Asp Lys Cys Ile Pro Ala Met 
            100                 105                 110         


Ile Ala Ile Gln Lys Asn Pro Asn Phe Lys Leu Gly Thr Ala Val Gln 
        115                 120                 125             


Asp Glu Val Ile Thr Ser Leu Gly Lys Leu Ile Gly Asn Ala Ser Ala 
    130                 135                 140                 


Asn Ala Glu Val Val Asn Asn Cys Val Pro Val Leu Lys Gln Phe Arg 
145                 150                 155                 160 


Glu Asn Leu Asn Gln Tyr Ala Pro Asp Tyr Val Lys Gly Thr Ala Val 
                165                 170                 175     


Asn Glu Leu Ile Lys Gly Ile Glu Phe Asp Phe Ser Gly Ala Ala Tyr 
            180                 185                 190         


Glu Lys Asp Val Lys Thr Met Pro Trp Tyr Gly Lys Ile Asp Pro Phe 
        195                 200                 205             


Ile Asn Glu Leu Lys Ala Leu Gly Leu Tyr Gly Asn Ile Thr Ser Ala 
    210                 215                 220                 


Thr Glu Trp Ala Ser Asp Val Gly Ile Tyr Tyr Leu Ser Lys Phe Gly 
225                 230                 235                 240 


Leu Tyr Ser Thr Asn Arg Asn Asp Ile Val Gln Ser Leu Glu Lys Ala 
                245                 250                 255     


Val Asp Met Tyr Lys Tyr Gly Lys Ile Ala Phe Val Ala Met Glu Arg 
            260                 265                 270         


Ile Thr Trp Asp Tyr Asp Gly Ile Gly Ser Asn Gly Lys Lys Val Asp 
        275                 280                 285             


His Asp Lys Phe Leu Asp Asp Ala Glu Lys His Tyr Leu Pro Lys Thr 
    290                 295                 300                 


Tyr Thr Phe Asp Asn Gly Thr Phe Ile Ile Arg Ala Gly Asp Lys Val 
305                 310                 315                 320 


Ser Glu Glu Lys Ile Lys Arg Leu Tyr Trp Ala Ser Arg Glu Val Lys 
                325                 330                 335     


Ser Gln Phe His Arg Val Val Gly Asn Asp Lys Ala Leu Glu Val Gly 
            340                 345                 350         


Asn Ala Asp Asp Val Leu Thr Met Lys Ile Phe Asn Ser Pro Glu Glu 
        355                 360                 365             


Tyr Lys Phe Asn Thr Asn Ile Asn Gly Val Ser Thr Asp Asn Gly Gly 
    370                 375                 380                 


Leu Tyr Ile Glu Pro Arg Gly Thr Phe Tyr Thr Tyr Glu Arg Thr Pro 
385                 390                 395                 400 


Gln Gln Ser Ile Phe Ser Leu Glu Glu Leu Phe Arg His Glu Tyr Thr 
                405                 410                 415     


His Tyr Leu Gln Ala Arg Tyr Leu Val Asp Gly Leu Trp Gly Gln Gly 
            420                 425                 430         


Pro Phe Tyr Glu Lys Asn Arg Leu Thr Trp Phe Asp Glu Gly Thr Ala 
        435                 440                 445             


Glu Phe Phe Ala Gly Ser Thr Arg Thr Ser Gly Val Leu Pro Arg Lys 
    450                 455                 460                 


Ser Ile Leu Gly Tyr Leu Ala Lys Asp Lys Val Asp His Arg Tyr Ser 
465                 470                 475                 480 


Leu Lys Lys Thr Leu Asn Ser Gly Tyr Asp Asp Ser Asp Trp Met Phe 
                485                 490                 495     


Tyr Asn Tyr Gly Phe Ala Val Ala His Tyr Leu Tyr Glu Lys Asp Met 
            500                 505                 510         


Pro Thr Phe Ile Lys Met Asn Lys Ala Ile Leu Asn Thr Asp Val Lys 
        515                 520                 525             


Ser Tyr Asp Glu Ile Ile Lys Lys Leu Ser Asp Asp Ala Asn Lys Asn 
    530                 535                 540                 


Thr Glu Tyr Gln Asn His Ile Gln Glu Leu Ala Asp Lys Tyr Gln Gly 
545                 550                 555                 560 


Ala Gly Ile Pro Leu Val Ser Asp Asp Tyr Leu Lys Asp His Gly Tyr 
                565                 570                 575     


Lys Lys Ala Ser Glu Val Tyr Ser Glu Ile Ser Lys Ala Ala Ser Leu 
            580                 585                 590         


Thr Asn Thr Ser Val Thr Ala Glu Lys Ser Gln Tyr Phe Asn Thr Phe 
        595                 600                 605             


Thr Leu Arg Gly Thr Tyr Thr Gly Glu Thr Ser Lys Gly Glu Phe Lys 
    610                 615                 620                 


Asp Trp Asp Glu Met Ser Lys Lys Leu Asp Gly Thr Leu Glu Ser Leu 
625                 630                 635                 640 


Ala Lys Asn Ser Trp Ser Gly Tyr Lys Thr Leu Thr Ala Tyr Phe Thr 
                645                 650                 655     


Asn Tyr Arg Val Thr Ser Asp Asn Lys Val Gln Tyr Asp Val Val Phe 
            660                 665                 670         


His Gly Val Leu Thr Asp Asn Ala Asp Ile Ser Asn Asn Lys Ala Pro 
        675                 680                 685             


Ile Ala Lys Val Thr Gly Pro Ser Thr Gly Ala Val Gly Arg Asn Ile 
    690                 695                 700                 


Glu Phe Ser Gly Lys Asp Ser Lys Asp Glu Asp Gly Lys Ile Val Ser 
705                 710                 715                 720 


Tyr Asp Trp Asp Phe Gly Asp Gly Ala Thr Ser Arg Gly Lys Asn Ser 
                725                 730                 735     


Val His Ala Tyr Lys Lys Ala Gly Thr Tyr Asn Val Thr Leu Lys Val 
            740                 745                 750         


Thr Asp Asp Lys Gly Ala Thr Ala Thr Glu Ser Phe Thr Ile Glu Ile 
        755                 760                 765             


Lys Asn Glu Asp Thr Thr Thr Pro Ile Thr Lys Glu Met Glu Pro Asn 
    770                 775                 780                 


Asp Asp Ile Lys Glu Ala Asn Gly Pro Ile Val Glu Gly Val Thr Val 
785                 790                 795                 800 


Lys Gly Asp Leu Asn Gly Ser Asp Asp Ala Asp Thr Phe Tyr Phe Asp 
                805                 810                 815     


Val Lys Glu Asp Gly Asp Val Thr Ile Glu Leu Pro Tyr Ser Gly Ser 
            820                 825                 830         


Ser Asn Phe Thr Trp Leu Val Tyr Lys Glu Gly Asp Asp Gln Asn His 
        835                 840                 845             


Ile Ala Ser Gly Ile Asp Lys Asn Asn Ser Lys Val Gly Thr Phe Lys 
    850                 855                 860                 


Ser Thr Lys Gly Arg His Tyr Val Phe Ile Tyr Lys His Asp Ser Ala 
865                 870                 875                 880 


Ser Asn Ile Ser Tyr Ser Leu Asn Ile Lys Gly Leu Gly Asn Glu Lys 
                885                 890                 895     


Leu Lys Glu Lys Glu Asn Asn Asp Ser Ser Asp Lys Ala Thr Val Ile 
            900                 905                 910         


Pro Asn Phe Asn Thr Thr Met Gln Gly Ser Leu Leu Gly Asp Asp Ser 
        915                 920                 925             


Arg Asp Tyr Tyr Ser Phe Glu Val Lys Glu Glu Gly Glu Val Asn Ile 
    930                 935                 940                 


Glu Leu Asp Lys Lys Asp Glu Phe Gly Val Thr Trp Thr Leu His Pro 
945                 950                 955                 960 


Glu Ser Asn Ile Asn Asp Arg Ile Thr Tyr Gly Gln Val Asp Gly Asn 
                965                 970                 975     


Lys Val Ser Asn Lys Val Lys Leu Arg Pro Gly Lys Tyr Tyr Leu Leu 
            980                 985                 990         


Val Tyr Lys Tyr Ser Gly Ser Gly  Asn Tyr Glu Leu Arg  Val Asn Lys 
        995                 1000                 1005             


<210>  5193
<211>  1124
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5193

Met Lys Lys Asn Ile Leu Lys Ile Leu Met Asp Ser Tyr Ser Lys Glu 
1               5                   10                  15      


Ser Lys Ile Gln Thr Val Arg Arg Val Thr Ser Val Ser Leu Leu Ala 
            20                  25                  30          


Val Tyr Leu Thr Met Asn Thr Ser Ser Leu Val Leu Ala Lys Pro Ile 
        35                  40                  45              


Glu Asn Thr Asn Asp Thr Ser Ile Lys Asn Val Glu Lys Leu Arg Asn 
    50                  55                  60                  


Ala Pro Asn Glu Glu Asn Ser Lys Lys Val Glu Asp Ser Lys Asn Asp 
65                  70                  75                  80  


Lys Val Glu His Val Lys Asn Ile Glu Glu Ala Lys Val Glu Gln Val 
                85                  90                  95      


Ala Pro Glu Val Lys Ser Lys Ser Thr Leu Arg Ser Ala Ser Arg Arg 
            100                 105                 110         


Arg Arg Lys Arg Ile Ala Asn Thr Asn Ser Glu Lys Tyr Asp Phe Glu 
        115                 120                 125             


Tyr Leu Asn Gly Leu Ser Tyr Thr Glu Leu Thr Asn Leu Ile Lys Asn 
    130                 135                 140                 


Ile Lys Trp Asn Gln Ile Asn Gly Leu Phe Asn Tyr Ser Thr Gly Ser 
145                 150                 155                 160 


Gln Lys Phe Phe Gly Asp Lys Asn Arg Val Gln Ala Ile Ile Asn Ala 
                165                 170                 175     


Leu Gln Glu Ser Gly Arg Thr Tyr Thr Ala Asn Asp Met Lys Gly Ile 
            180                 185                 190         


Glu Thr Phe Thr Glu Val Leu Arg Ala Gly Phe Tyr Leu Gly Tyr Tyr 
        195                 200                 205             


Asn Asp Gly Leu Ser Tyr Leu Asn Asp Arg Asn Phe Gln Asp Lys Cys 
    210                 215                 220                 


Ile Pro Ala Met Ile Ala Ile Gln Lys Asn Pro Asn Phe Lys Leu Gly 
225                 230                 235                 240 


Thr Ala Val Gln Asp Glu Val Ile Thr Ser Leu Gly Lys Leu Ile Gly 
                245                 250                 255     


Asn Ala Ser Ala Asn Ala Glu Val Val Asn Asn Cys Val Pro Val Leu 
            260                 265                 270         


Lys Gln Phe Arg Glu Asn Leu Asn Gln Tyr Ala Pro Asp Tyr Val Lys 
        275                 280                 285             


Gly Thr Ala Val Asn Glu Leu Ile Lys Gly Ile Glu Phe Asp Phe Ser 
    290                 295                 300                 


Gly Ala Ala Tyr Glu Lys Asp Val Lys Thr Met Pro Trp Tyr Gly Lys 
305                 310                 315                 320 


Ile Asp Pro Phe Ile Asn Glu Leu Lys Ala Leu Gly Leu Tyr Gly Asn 
                325                 330                 335     


Ile Thr Ser Ala Thr Glu Trp Ala Ser Asp Val Gly Ile Tyr Tyr Leu 
            340                 345                 350         


Ser Lys Phe Gly Leu Tyr Ser Thr Asn Arg Asn Asp Ile Val Gln Ser 
        355                 360                 365             


Leu Glu Lys Ala Val Asp Met Tyr Lys Tyr Gly Lys Ile Ala Phe Val 
    370                 375                 380                 


Ala Met Glu Arg Ile Thr Trp Asp Tyr Asp Gly Ile Gly Ser Asn Gly 
385                 390                 395                 400 


Lys Lys Val Asp His Asp Lys Phe Leu Asp Asp Ala Glu Lys His Tyr 
                405                 410                 415     


Leu Pro Lys Thr Tyr Thr Phe Asp Asn Gly Thr Phe Ile Ile Arg Ala 
            420                 425                 430         


Gly Asp Lys Val Ser Glu Glu Lys Ile Lys Arg Leu Tyr Trp Ala Ser 
        435                 440                 445             


Arg Glu Val Lys Ser Gln Phe His Arg Val Val Gly Asn Asp Lys Ala 
    450                 455                 460                 


Leu Glu Val Gly Asn Ala Asp Asp Val Leu Thr Met Lys Ile Phe Asn 
465                 470                 475                 480 


Ser Pro Glu Glu Tyr Lys Phe Asn Thr Asn Ile Asn Gly Val Ser Thr 
                485                 490                 495     


Asp Asn Gly Gly Leu Tyr Ile Glu Pro Arg Gly Thr Phe Tyr Thr Tyr 
            500                 505                 510         


Glu Arg Thr Pro Gln Gln Ser Ile Phe Ser Leu Glu Glu Leu Phe Arg 
        515                 520                 525             


His Glu Tyr Thr His Tyr Leu Gln Ala Arg Tyr Leu Val Asp Gly Leu 
    530                 535                 540                 


Trp Gly Gln Gly Pro Phe Tyr Glu Lys Asn Arg Leu Thr Trp Phe Asp 
545                 550                 555                 560 


Glu Gly Thr Ala Glu Phe Phe Ala Gly Ser Thr Arg Thr Ser Gly Val 
                565                 570                 575     


Leu Pro Arg Lys Ser Ile Leu Gly Tyr Leu Ala Lys Asp Lys Val Asp 
            580                 585                 590         


His Arg Tyr Ser Leu Lys Lys Thr Leu Asn Ser Gly Tyr Asp Asp Ser 
        595                 600                 605             


Asp Trp Met Phe Tyr Asn Tyr Gly Phe Ala Val Ala His Tyr Leu Tyr 
    610                 615                 620                 


Glu Lys Asp Met Pro Thr Phe Ile Lys Met Asn Lys Ala Ile Leu Asn 
625                 630                 635                 640 


Thr Asp Val Lys Ser Tyr Asp Glu Ile Ile Lys Lys Leu Ser Asp Asp 
                645                 650                 655     


Ala Asn Lys Asn Thr Glu Tyr Gln Asn His Ile Gln Glu Leu Ala Asp 
            660                 665                 670         


Lys Tyr Gln Gly Ala Gly Ile Pro Leu Val Ser Asp Asp Tyr Leu Lys 
        675                 680                 685             


Asp His Gly Tyr Lys Lys Ala Ser Glu Val Tyr Ser Glu Ile Ser Lys 
    690                 695                 700                 


Ala Ala Ser Leu Thr Asn Thr Ser Val Thr Ala Glu Lys Ser Gln Tyr 
705                 710                 715                 720 


Phe Asn Thr Phe Thr Leu Arg Gly Thr Tyr Thr Gly Glu Thr Ser Lys 
                725                 730                 735     


Gly Glu Phe Lys Asp Trp Asp Glu Met Ser Lys Lys Leu Asp Gly Thr 
            740                 745                 750         


Leu Glu Ser Leu Ala Lys Asn Ser Trp Ser Gly Tyr Lys Thr Leu Thr 
        755                 760                 765             


Ala Tyr Phe Thr Asn Tyr Arg Val Thr Ser Asp Asn Lys Val Gln Tyr 
    770                 775                 780                 


Asp Val Val Phe His Gly Val Leu Thr Asp Asn Ala Asp Ile Ser Asn 
785                 790                 795                 800 


Asn Lys Ala Pro Ile Ala Lys Val Thr Gly Pro Ser Thr Gly Ala Val 
                805                 810                 815     


Gly Arg Asn Ile Glu Phe Ser Gly Lys Asp Ser Lys Asp Glu Asp Gly 
            820                 825                 830         


Lys Ile Val Ser Tyr Asp Trp Asp Phe Gly Asp Gly Ala Thr Ser Arg 
        835                 840                 845             


Gly Lys Asn Ser Val His Ala Tyr Lys Lys Ala Gly Thr Tyr Asn Val 
    850                 855                 860                 


Thr Leu Lys Val Thr Asp Asp Lys Gly Ala Thr Ala Thr Glu Ser Phe 
865                 870                 875                 880 


Thr Ile Glu Ile Lys Asn Glu Asp Thr Thr Thr Pro Ile Thr Lys Glu 
                885                 890                 895     


Met Glu Pro Asn Asp Asp Ile Lys Glu Ala Asn Gly Pro Ile Val Glu 
            900                 905                 910         


Gly Val Thr Val Lys Gly Asp Leu Asn Gly Ser Asp Asp Ala Asp Thr 
        915                 920                 925             


Phe Tyr Phe Asp Val Lys Glu Asp Gly Asp Val Thr Ile Glu Leu Pro 
    930                 935                 940                 


Tyr Ser Gly Ser Ser Asn Phe Thr Trp Leu Val Tyr Lys Glu Gly Asp 
945                 950                 955                 960 


Asp Gln Asn His Ile Ala Ser Gly Ile Asp Lys Asn Asn Ser Lys Val 
                965                 970                 975     


Gly Thr Phe Lys Ser Thr Lys Gly Arg His Tyr Val Phe Ile Tyr Lys 
            980                 985                 990         


His Asp Ser Ala Ser Asn Ile Ser  Tyr Ser Leu Asn Ile  Lys Gly Leu 
        995                 1000                 1005             


Gly Asn  Glu Lys Leu Lys Glu  Lys Glu Asn Asn Asp  Ser Ser Asp 
    1010                 1015                 1020             


Lys Ala  Thr Val Ile Pro Asn  Phe Asn Thr Thr Met  Gln Gly Ser 
    1025                 1030                 1035             


Leu Leu  Gly Asp Asp Ser Arg  Asp Tyr Tyr Ser Phe  Glu Val Lys 
    1040                 1045                 1050             


Glu Glu  Gly Glu Val Asn Ile  Glu Leu Asp Lys Lys  Asp Glu Phe 
    1055                 1060                 1065             


Gly Val  Thr Trp Thr Leu His  Pro Glu Ser Asn Ile  Asn Asp Arg 
    1070                 1075                 1080             


Ile Thr  Tyr Gly Gln Val Asp  Gly Asn Lys Val Ser  Asn Lys Val 
    1085                 1090                 1095             


Lys Leu  Arg Pro Gly Lys Tyr  Tyr Leu Leu Val Tyr  Lys Tyr Ser 
    1100                 1105                 1110             


Gly Ser  Gly Asn Tyr Glu Leu  Arg Val Asn Lys 
    1115                 1120                 


<210>  5194
<211>  981
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5194

Val Gln Asn Glu Ser Lys Arg Tyr Thr Val Ser Tyr Leu Lys Thr Leu 
1               5                   10                  15      


Asn Tyr Tyr Asp Leu Val Asp Leu Leu Val Lys Thr Glu Ile Glu Asn 
            20                  25                  30          


Leu Pro Asp Leu Phe Gln Tyr Ser Ser Asp Ala Lys Glu Phe Tyr Gly 
        35                  40                  45              


Asn Lys Thr Arg Met Ser Phe Ile Met Asp Glu Ile Gly Arg Arg Ala 
    50                  55                  60                  


Pro Gln Tyr Thr Glu Ile Asp His Lys Gly Ile Pro Thr Leu Val Glu 
65                  70                  75                  80  


Val Val Arg Ala Gly Phe Tyr Leu Gly Phe His Asn Lys Glu Leu Asn 
                85                  90                  95      


Glu Ile Asn Lys Arg Ser Phe Lys Glu Arg Val Ile Pro Ser Ile Leu 
            100                 105                 110         


Ala Ile Gln Lys Asn Pro Asn Phe Lys Leu Gly Thr Glu Val Gln Asp 
        115                 120                 125             


Lys Ile Val Ser Ala Thr Gly Leu Leu Ala Gly Asn Glu Thr Ala Pro 
    130                 135                 140                 


Pro Glu Val Val Asn Asn Phe Thr Pro Ile Leu Gln Asp Cys Ile Lys 
145                 150                 155                 160 


Asn Ile Asp Arg Tyr Ala Leu Asp Asp Leu Lys Ser Lys Ala Leu Phe 
                165                 170                 175     


Asn Val Leu Ala Ala Pro Thr Tyr Asp Ile Thr Glu Tyr Leu Arg Ala 
            180                 185                 190         


Thr Lys Glu Lys Pro Glu Asn Thr Pro Trp Tyr Gly Lys Ile Asp Gly 
        195                 200                 205             


Phe Ile Asn Glu Leu Lys Lys Leu Ala Leu Tyr Gly Lys Ile Asn Asp 
    210                 215                 220                 


Asn Asn Ser Trp Ile Ile Asp Asn Gly Ile Tyr His Ile Ala Pro Leu 
225                 230                 235                 240 


Gly Lys Leu His Ser Asn Asn Lys Ile Gly Ile Glu Thr Leu Thr Glu 
                245                 250                 255     


Val Met Lys Val Tyr Pro Tyr Leu Ser Met Gln His Leu Gln Ser Ala 
            260                 265                 270         


Asp Gln Ile Lys Arg His Tyr Asp Ser Lys Asp Ala Glu Gly Asn Lys 
        275                 280                 285             


Ile Pro Leu Asp Lys Phe Lys Lys Glu Gly Lys Glu Lys Tyr Cys Pro 
    290                 295                 300                 


Lys Thr Tyr Thr Phe Asp Asp Gly Lys Val Ile Ile Lys Ala Gly Ala 
305                 310                 315                 320 


Arg Val Glu Glu Glu Lys Val Lys Arg Leu Tyr Trp Ala Ser Lys Glu 
                325                 330                 335     


Val Asn Ser Gln Phe Phe Arg Val Tyr Gly Ile Asp Lys Pro Leu Glu 
            340                 345                 350         


Glu Gly Asn Pro Asp Asp Ile Leu Thr Met Val Ile Tyr Asn Ser Pro 
        355                 360                 365             


Glu Glu Tyr Lys Leu Asn Ser Val Leu Tyr Gly Tyr Asp Thr Asn Asn 
    370                 375                 380                 


Gly Gly Met Tyr Ile Glu Pro Glu Gly Thr Phe Phe Thr Tyr Glu Arg 
385                 390                 395                 400 


Glu Ala Gln Glu Ser Thr Tyr Thr Leu Glu Glu Leu Phe Arg His Glu 
                405                 410                 415     


Tyr Thr His Tyr Leu Gln Gly Arg Tyr Ala Val Pro Gly Gln Trp Gly 
            420                 425                 430         


Arg Thr Lys Leu Tyr Asp Asn Asp Arg Leu Thr Trp Tyr Glu Glu Gly 
        435                 440                 445             


Gly Ala Glu Leu Phe Ala Gly Ser Thr Arg Thr Ser Gly Ile Leu Pro 
    450                 455                 460                 


Arg Lys Ser Ile Val Ser Asn Ile His Asn Thr Thr Arg Asn Asn Arg 
465                 470                 475                 480 


Tyr Lys Leu Ser Asp Thr Val His Ser Lys Tyr Gly Ala Ser Phe Glu 
                485                 490                 495     


Phe Tyr Asn Tyr Ala Cys Met Phe Met Asp Tyr Met Tyr Asn Lys Asp 
            500                 505                 510         


Met Gly Ile Leu Asn Lys Leu Asn Asp Leu Ala Lys Asn Asn Asp Val 
        515                 520                 525             


Asp Gly Tyr Asp Asn Tyr Ile Arg Asp Leu Ser Ser Asn Tyr Ala Leu 
    530                 535                 540                 


Asn Asp Lys Tyr Gln Asp His Met Gln Glu Arg Ile Asp Asn Tyr Glu 
545                 550                 555                 560 


Asn Leu Thr Val Pro Phe Val Ala Asp Asp Tyr Leu Val Arg His Ala 
                565                 570                 575     


Tyr Lys Asn Pro Asn Glu Ile Tyr Ser Glu Ile Ser Glu Val Ala Lys 
            580                 585                 590         


Leu Lys Asp Ala Lys Ser Glu Val Lys Lys Ser Gln Tyr Phe Ser Thr 
        595                 600                 605             


Phe Thr Leu Arg Gly Ser Tyr Thr Gly Gly Ala Ser Lys Gly Lys Leu 
    610                 615                 620                 


Glu Asp Gln Lys Ala Met Asn Lys Phe Ile Asp Asp Ser Leu Lys Lys 
625                 630                 635                 640 


Leu Asp Thr Tyr Ser Trp Ser Gly Tyr Lys Thr Leu Thr Ala Tyr Phe 
                645                 650                 655     


Thr Asn Tyr Lys Val Asp Ser Ser Asn Arg Val Thr Tyr Asp Val Val 
            660                 665                 670         


Phe His Gly Tyr Leu Pro Asn Glu Gly Asp Ser Lys Asn Ser Leu Pro 
        675                 680                 685             


Tyr Gly Lys Ile Asn Gly Thr Tyr Lys Gly Thr Glu Lys Glu Lys Ile 
    690                 695                 700                 


Lys Phe Ser Ser Glu Gly Ser Phe Asp Pro Asp Gly Lys Ile Val Ser 
705                 710                 715                 720 


Tyr Glu Trp Asp Phe Gly Asp Gly Asn Lys Ser Asn Glu Glu Asn Pro 
                725                 730                 735     


Glu His Ser Tyr Asp Lys Val Gly Thr Tyr Thr Val Lys Leu Lys Val 
            740                 745                 750         


Thr Asp Asp Lys Gly Glu Ser Ser Val Ser Thr Thr Thr Ala Glu Ile 
        755                 760                 765             


Lys Asp Leu Ser Glu Asn Lys Leu Pro Val Ile Tyr Met His Val Pro 
    770                 775                 780                 


Lys Ser Gly Ala Leu Asn Gln Lys Val Val Phe Tyr Gly Lys Gly Thr 
785                 790                 795                 800 


Tyr Asp Pro Asp Gly Ser Ile Ala Gly Tyr Gln Trp Asp Phe Gly Asp 
                805                 810                 815     


Gly Ser Asp Phe Ser Ser Glu Gln Asn Pro Ser His Val Tyr Thr Lys 
            820                 825                 830         


Lys Gly Glu Tyr Thr Val Thr Leu Arg Val Met Asp Ser Ser Gly Gln 
        835                 840                 845             


Met Ser Glu Lys Thr Met Lys Ile Lys Ile Thr Asp Pro Val Tyr Pro 
    850                 855                 860                 


Ile Gly Thr Glu Lys Glu Pro Asn Asn Ser Lys Glu Thr Ala Ser Gly 
865                 870                 875                 880 


Pro Ile Val Pro Gly Ile Pro Val Ser Gly Thr Ile Glu Asn Thr Ser 
                885                 890                 895     


Asp Gln Asp Tyr Phe Tyr Phe Asp Val Ile Thr Pro Gly Glu Val Lys 
            900                 905                 910         


Ile Asp Ile Asn Lys Leu Gly Tyr Gly Gly Ala Thr Trp Val Val Tyr 
        915                 920                 925             


Asp Glu Asn Asn Asn Ala Val Ser Tyr Ala Thr Asp Asp Gly Gln Asn 
    930                 935                 940                 


Leu Ser Gly Lys Phe Lys Ala Asp Lys Pro Gly Arg Tyr Tyr Ile His 
945                 950                 955                 960 


Leu Tyr Met Phe Asn Gly Ser Tyr Met Pro Tyr Arg Ile Asn Ile Glu 
                965                 970                 975     


Gly Ser Val Gly Arg 
            980     


<210>  5195
<211>  1027
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5195

Met Lys Arg Lys Cys Leu Ser Lys Arg Leu Met Leu Ala Ile Thr Met 
1               5                   10                  15      


Ala Thr Ile Phe Thr Val Asn Ser Thr Leu Pro Ile Tyr Ala Ala Val 
            20                  25                  30          


Asp Lys Asn Asn Ala Thr Ala Ala Arg Arg Arg Arg Lys Arg Val Gln 
        35                  40                  45              


Asn Glu Ser Lys Arg Tyr Thr Val Ser Tyr Leu Lys Thr Leu Asn Tyr 
    50                  55                  60                  


Tyr Asp Leu Val Asp Leu Leu Val Lys Thr Glu Ile Glu Asn Leu Pro 
65                  70                  75                  80  


Asp Leu Phe Gln Tyr Ser Ser Asp Ala Lys Glu Phe Tyr Gly Asn Lys 
                85                  90                  95      


Thr Arg Met Ser Phe Ile Met Asp Glu Ile Gly Arg Arg Ala Pro Gln 
            100                 105                 110         


Tyr Thr Glu Ile Asp His Lys Gly Ile Pro Thr Leu Val Glu Val Val 
        115                 120                 125             


Arg Ala Gly Phe Tyr Leu Gly Phe His Asn Lys Glu Leu Asn Glu Ile 
    130                 135                 140                 


Asn Lys Arg Ser Phe Lys Glu Arg Val Ile Pro Ser Ile Leu Ala Ile 
145                 150                 155                 160 


Gln Lys Asn Pro Asn Phe Lys Leu Gly Thr Glu Val Gln Asp Lys Ile 
                165                 170                 175     


Val Ser Ala Thr Gly Leu Leu Ala Gly Asn Glu Thr Ala Pro Pro Glu 
            180                 185                 190         


Val Val Asn Asn Phe Thr Pro Ile Leu Gln Asp Cys Ile Lys Asn Ile 
        195                 200                 205             


Asp Arg Tyr Ala Leu Asp Asp Leu Lys Ser Lys Ala Leu Phe Asn Val 
    210                 215                 220                 


Leu Ala Ala Pro Thr Tyr Asp Ile Thr Glu Tyr Leu Arg Ala Thr Lys 
225                 230                 235                 240 


Glu Lys Pro Glu Asn Thr Pro Trp Tyr Gly Lys Ile Asp Gly Phe Ile 
                245                 250                 255     


Asn Glu Leu Lys Lys Leu Ala Leu Tyr Gly Lys Ile Asn Asp Asn Asn 
            260                 265                 270         


Ser Trp Ile Ile Asp Asn Gly Ile Tyr His Ile Ala Pro Leu Gly Lys 
        275                 280                 285             


Leu His Ser Asn Asn Lys Ile Gly Ile Glu Thr Leu Thr Glu Val Met 
    290                 295                 300                 


Lys Val Tyr Pro Tyr Leu Ser Met Gln His Leu Gln Ser Ala Asp Gln 
305                 310                 315                 320 


Ile Lys Arg His Tyr Asp Ser Lys Asp Ala Glu Gly Asn Lys Ile Pro 
                325                 330                 335     


Leu Asp Lys Phe Lys Lys Glu Gly Lys Glu Lys Tyr Cys Pro Lys Thr 
            340                 345                 350         


Tyr Thr Phe Asp Asp Gly Lys Val Ile Ile Lys Ala Gly Ala Arg Val 
        355                 360                 365             


Glu Glu Glu Lys Val Lys Arg Leu Tyr Trp Ala Ser Lys Glu Val Asn 
    370                 375                 380                 


Ser Gln Phe Phe Arg Val Tyr Gly Ile Asp Lys Pro Leu Glu Glu Gly 
385                 390                 395                 400 


Asn Pro Asp Asp Ile Leu Thr Met Val Ile Tyr Asn Ser Pro Glu Glu 
                405                 410                 415     


Tyr Lys Leu Asn Ser Val Leu Tyr Gly Tyr Asp Thr Asn Asn Gly Gly 
            420                 425                 430         


Met Tyr Ile Glu Pro Glu Gly Thr Phe Phe Thr Tyr Glu Arg Glu Ala 
        435                 440                 445             


Gln Glu Ser Thr Tyr Thr Leu Glu Glu Leu Phe Arg His Glu Tyr Thr 
    450                 455                 460                 


His Tyr Leu Gln Gly Arg Tyr Ala Val Pro Gly Gln Trp Gly Arg Thr 
465                 470                 475                 480 


Lys Leu Tyr Asp Asn Asp Arg Leu Thr Trp Tyr Glu Glu Gly Gly Ala 
                485                 490                 495     


Glu Leu Phe Ala Gly Ser Thr Arg Thr Ser Gly Ile Leu Pro Arg Lys 
            500                 505                 510         


Ser Ile Val Ser Asn Ile His Asn Thr Thr Arg Asn Asn Arg Tyr Lys 
        515                 520                 525             


Leu Ser Asp Thr Val His Ser Lys Tyr Gly Ala Ser Phe Glu Phe Tyr 
    530                 535                 540                 


Asn Tyr Ala Cys Met Phe Met Asp Tyr Met Tyr Asn Lys Asp Met Gly 
545                 550                 555                 560 


Ile Leu Asn Lys Leu Asn Asp Leu Ala Lys Asn Asn Asp Val Asp Gly 
                565                 570                 575     


Tyr Asp Asn Tyr Ile Arg Asp Leu Ser Ser Asn Tyr Ala Leu Asn Asp 
            580                 585                 590         


Lys Tyr Gln Asp His Met Gln Glu Arg Ile Asp Asn Tyr Glu Asn Leu 
        595                 600                 605             


Thr Val Pro Phe Val Ala Asp Asp Tyr Leu Val Arg His Ala Tyr Lys 
    610                 615                 620                 


Asn Pro Asn Glu Ile Tyr Ser Glu Ile Ser Glu Val Ala Lys Leu Lys 
625                 630                 635                 640 


Asp Ala Lys Ser Glu Val Lys Lys Ser Gln Tyr Phe Ser Thr Phe Thr 
                645                 650                 655     


Leu Arg Gly Ser Tyr Thr Gly Gly Ala Ser Lys Gly Lys Leu Glu Asp 
            660                 665                 670         


Gln Lys Ala Met Asn Lys Phe Ile Asp Asp Ser Leu Lys Lys Leu Asp 
        675                 680                 685             


Thr Tyr Ser Trp Ser Gly Tyr Lys Thr Leu Thr Ala Tyr Phe Thr Asn 
    690                 695                 700                 


Tyr Lys Val Asp Ser Ser Asn Arg Val Thr Tyr Asp Val Val Phe His 
705                 710                 715                 720 


Gly Tyr Leu Pro Asn Glu Gly Asp Ser Lys Asn Ser Leu Pro Tyr Gly 
                725                 730                 735     


Lys Ile Asn Gly Thr Tyr Lys Gly Thr Glu Lys Glu Lys Ile Lys Phe 
            740                 745                 750         


Ser Ser Glu Gly Ser Phe Asp Pro Asp Gly Lys Ile Val Ser Tyr Glu 
        755                 760                 765             


Trp Asp Phe Gly Asp Gly Asn Lys Ser Asn Glu Glu Asn Pro Glu His 
    770                 775                 780                 


Ser Tyr Asp Lys Val Gly Thr Tyr Thr Val Lys Leu Lys Val Thr Asp 
785                 790                 795                 800 


Asp Lys Gly Glu Ser Ser Val Ser Thr Thr Thr Ala Glu Ile Lys Asp 
                805                 810                 815     


Leu Ser Glu Asn Lys Leu Pro Val Ile Tyr Met His Val Pro Lys Ser 
            820                 825                 830         


Gly Ala Leu Asn Gln Lys Val Val Phe Tyr Gly Lys Gly Thr Tyr Asp 
        835                 840                 845             


Pro Asp Gly Ser Ile Ala Gly Tyr Gln Trp Asp Phe Gly Asp Gly Ser 
    850                 855                 860                 


Asp Phe Ser Ser Glu Gln Asn Pro Ser His Val Tyr Thr Lys Lys Gly 
865                 870                 875                 880 


Glu Tyr Thr Val Thr Leu Arg Val Met Asp Ser Ser Gly Gln Met Ser 
                885                 890                 895     


Glu Lys Thr Met Lys Ile Lys Ile Thr Asp Pro Val Tyr Pro Ile Gly 
            900                 905                 910         


Thr Glu Lys Glu Pro Asn Asn Ser Lys Glu Thr Ala Ser Gly Pro Ile 
        915                 920                 925             


Val Pro Gly Ile Pro Val Ser Gly Thr Ile Glu Asn Thr Ser Asp Gln 
    930                 935                 940                 


Asp Tyr Phe Tyr Phe Asp Val Ile Thr Pro Gly Glu Val Lys Ile Asp 
945                 950                 955                 960 


Ile Asn Lys Leu Gly Tyr Gly Gly Ala Thr Trp Val Val Tyr Asp Glu 
                965                 970                 975     


Asn Asn Asn Ala Val Ser Tyr Ala Thr Asp Asp Gly Gln Asn Leu Ser 
            980                 985                 990         


Gly Lys Phe Lys Ala Asp Lys Pro  Gly Arg Tyr Tyr Ile  His Leu Tyr 
        995                 1000                 1005             


Met Phe  Asn Gly Ser Tyr Met  Pro Tyr Arg Ile Asn  Ile Glu Gly 
    1010                 1015                 1020             


Ser Val  Gly Arg 
    1025         


<210>  5196
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5196
auagcgaaua cuaauucuga gaaauaugau uuugaguauu uaaaugguuu gagcuauacu       60

gaacuuacaa auuuaauuaa aaauauaaag uggaaucaaa uuaaugguuu auuuaauuau      120

aguacagguu cucaaaaguu cuuuggagau aaaaaucgug uacaagcuau aauuaaugcu      180

uuacaagaaa guggaagaac uuacacugca aaugauauga aggguauaga aacuuucacu      240

gagguuuuaa gagcugguuu uuauuuaggg uacuauaaug augguuuauc uuauuuaaau      300

gauagaaacu uccaagauaa auguauaccu gcaaugauug caauucaaaa aaauccuaac      360

uuuaagcuag gaacugcagu ucaagaugaa guuauaacuu cuuuaggaaa acuaauagga      420

aaugcuucug cuaaugcuga aguaguuaau aauuguguac caguucuaaa acaauuuaga      480

gaaaacuuaa aucaauaugc uccugauuac guuaaaggaa cagcuguaaa ugaauuaauu      540

aaagguauug aauucgauuu uucuggugcu gcauaugaaa aagauguuaa gacaaugccu      600

ugguauggaa aaauugaucc auuuauaaau gaacuuaagg ccuuaggucu auauggaaau      660

auaacaagug caacugagug ggcaucugau guuggaauau acuauuuaag uaaauucggu      720

cuuuacucaa cuaaccgaaa ugacauagua cagucacuug aaaaggcugu agauauguau      780

aaguauggua aaauagccuu uguagcaaug gagagaauaa cuugggauua ugaugggauu      840

gguucuaaug guaaaaaggu ggaucacgau aaguucuuag augaugcuga aaaacauuau      900

cugccaaaga cauauacuuu ugauaaugga accuuuauua uaagagcagg ggauaaggua      960

uccgaagaaa aaauaaaaag gcuauauugg gcaucaagag aagugaaguc ucaauuccau     1020

agaguaguug gcaaugauaa agcuuuagag gugggaaaug ccgaugaugu uuuaacuaug     1080

aaaauauuua auagcccaga agaauauaaa uuuaauacca auauaaaugg uguaagcacu     1140

gauaauggug gucuauauau agaaccaaga gggacuuucu acacuuauga gagaacaccu     1200

caacaaagua uauuuagucu ugaagaauug uuuagacaug aauauacuca cuauuuacaa     1260

gcgagauauc uuguagaugg uuuauggggg caagguccau uuuaugaaaa aaauagauua     1320

acuugguuug augaagguac agcugaauuc uuugcaggau cuacccguac aucugguguu     1380

uuaccaagaa aaucaauauu aggauauuug gcuaaggaua aaguagauca uagauacuca     1440

uuaaagaaga cucuuaauuc aggguaugau gacagugauu ggauguucua uaauuaugga     1500

uuugcaguug cacauuaccu auaugaaaaa gauaugccua cauuuauuaa gaugaauaaa     1560

gcuauauuga auacagaugu gaaaucuuau gaugaaauaa uaaaaaaauu aagugaugau     1620

gcaaauaaaa auacagaaua ucaaaaccau auucaagagu uagcagauaa auaucaagga     1680

gcaggcauac cucuaguauc agaugauuac uuaaaagauc auggauauaa gaaagcaucu     1740

gaaguauauu cugaaauuuc aaaagcugcu ucucuuacaa acacuagugu aacagcagaa     1800

aaaucucaau auuuuaacac auucacuuua agaggaacuu auacagguga aacuucuaaa     1860

ggugaauuua aagauuggga ugaaaugagu aaaaaauuag auggaacuuu ggagucccuu     1920

gcuaaaaauu cuuggagugg auacaaaacu uuaacagcau acuuuacgaa uuauagaguu     1980

acaagcgaua auaaaguuca auaugaugua guuuuccaug ggguuuuaac agauaaugcg     2040

gauauuagua acaauaaggc uccaauagca aagguaacug gaccaagcac uggugcugua     2100

ggaagaaaua uugaauuuag uggaaaagau aguaaagaug aagaugguaa aauaguauca     2160

uaugauuggg auuuuggcga uggugcaacu aguagaggca aaaauucagu acaugcuuac     2220

aaaaaagcag gaacauauaa uguuacauua aaaguaacug acgauaaggg ugcaacagcu     2280

acagaaagcu uuacuauaga aauaaagaac gaagauacaa caacaccuau aacuaaagaa     2340

auggaaccua augaugauau aaaagaggcu aaugguccaa uaguugaagg uguuacugua     2400

aaaggugauu uaaaugguuc ugaugaugcu gauaccuucu auuuugaugu aaaagaagau     2460

ggugauguua caauugaacu uccuuauuca gggucaucua auuucacaug guuaguuuau     2520

aaagagggag acgaucaaaa ccauauugca agugguauag auaagaauaa cucaaaaguu     2580

ggaacauuua aaucuacaaa aggaagacau uauguguuua uauauaaaca cgauucugcu     2640

ucaaauauau ccuauucuuu aaacauaaaa ggauuaggua acgagaaauu gaaggaaaaa     2700

gaaaauaaug auucuucuga uaaagcuaca guuauaccaa auuucaauac cacuaugcaa     2760

gguucacuuu uaggugauga uucaagagau uauuauucuu uugagguuaa ggaagaaggc     2820

gaaguuaaua uagaacuaga uaaaaaggau gaauuuggug uaacauggac acuacaucca     2880

gagucaaaua uuaaugacag aauaacuuac ggacaaguug augguaauaa gguaucuaau     2940

aaaguuaaau uaagaccagg aaaauauuau cuacuuguuu auaaauacuc aggaucagga     3000

aacuaugagu uaaggguaaa uaaauaa                                         3027


<210>  5197
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5197
auagcgaaua cuaauucuga gaaauaugau uuugaguauu uaaaugguuu gagcuauacu       60

gaacuuacaa auuuaauuaa aaauauaaag uggaaucaaa uuaaugguuu auuuaauuau      120

aguacagguu cucaaaaguu cuuuggagau aaaaaucgug uacaagcuau aauuaaugcu      180

uuacaagaaa guggaagaac uuacacugca aaugauauga aggguauaga aacuuucacu      240

gagguuuuaa gagcugguuu uuauuuaggg uacuauaaug augguuuauc uuauuuaaau      300

gauagaaacu uccaagauaa auguauaccu gcaaugauug caauucaaaa aaauccuaac      360

uuuaagcuag gaacugcagu ucaagaugaa guuauaacuu cuuuaggaaa acuaauagga      420

aaugcuucug cuaaugcuga aguaguuaau aauuguguac caguucuaaa acaauuuaga      480

gaaaacuuaa aucaauaugc uccugauuac guuaaaggaa cagcuguaaa ugaauuaauu      540

aaagguauug aguucgauuu uucuggugcu gcauaugaaa aagauguuaa gacaaugccu      600

ugguauggaa aaauugaucc auuuauaaau gaacuuaagg ccuuaggucu auauggaaau      660

auaacaagug caacugagug ggcaucugau guuggaauau acuauuuaag uaaauucggu      720

cuuuacucaa cuaaccgaaa ugacauagua cagucacuug aaaaggcugu agauauguau      780

aaguauggua aaauagccuu uguagcaaug gagagaauaa cuugggauua ugaugggauu      840

gguucuaaug guaaaaaggu ggaucacgau aaguucuuag augaugcuga aaaacauuau      900

cugccaaaga cauauacuuu ugauaaugga accuuuauua uaagagcagg ggauaaggua      960

uccgaagaaa aaauaaaaag gcuauauugg gcaucaagag aagugaaguc ucaauuccau     1020

agaguaguug gcaaugauaa agcauuagag gugggaaaug ccgaugaugu uuuaacuaug     1080

aaaauauuua auagcccaga agaauauaaa uuuaauacca auauaaaugg uguaagcacu     1140

gauaauggug gucuauauau agaaccaaga gggacuuucu acacuuauga gagaacaccu     1200

caacaaagua uauuuagucu ugaagaauug uuuagacaug aauauacuca cuauuuacaa     1260

gcgagauauc uuguagaugg uuuauggggg caagguccau uuuaugaaaa aaauagauua     1320

acuugguuug augaagguac agcugaguuc uuugcaggau cuacccguac aucugguguu     1380

uuaccaagaa aaucaauauu aggauauuug gcuaaggaua aaguagauca uagauacuca     1440

uuaaagaaga cucuuaauuc aggguaugau gacagugauu ggauguucua uaauuaugga     1500

uuugcaguug cacauuaccu auaugaaaaa gauaugccua cauuuauuaa gaugaauaaa     1560

gcuauauuga auacagaugu gaaaucuuau gaugaaauaa uaaaaaaauu aagugaugau     1620

gcaaauaaaa auacagaaua ucaaaaccau auucaagagu uagcagauaa auaucaagga     1680

gcaggcauac cucuaguauc agaugauuac uuaaaagauc auggauauaa gaaagcaucu     1740

gaaguauauu cugaaauuuc aaaagcugcu ucucuuacaa acacaagugu aacagcagaa     1800

aaaucucaau auuuuaacac auucacuuua agaggaacuu auacagguga aacuucuaaa     1860

ggugaauuua aagauuggga ugaaaugagu aaaaaauuag auggaacuuu ggagucccuu     1920

gcuaaaaauu cuuggagugg auacaaaacu uuaacagcau acuuuacgaa uuauagaguu     1980

acaagcgaua auaaaguuca auaugaugua guuuuccaug ggguuuuaac agauaaugcg     2040

gauauuagua acaauaaggc uccaauagca aagguaacug gaccaagcac uggugcugua     2100

ggaagaaaua uugaauuuag uggaaaagau aguaaagaug aagaugguaa aauaguauca     2160

uaugauuggg auuuuggcga uggugcaaca aguagaggca aaaauucagu acaugcuuac     2220

aaaaaagcag gaacauauaa uguuacauua aaaguaacug acgauaaggg ugcaacagcu     2280

acagagagcu uuacuauaga aauaaagaac gaagauacaa caacaccuau aacuaaagaa     2340

auggaaccua augaugauau aaaagaggcu aaugguccaa uaguugaagg uguuacugua     2400

aaaggugauu uaaaugguuc ugaugaugcu gauaccuucu auuuugaugu aaaagaagau     2460

ggugauguua caauugaacu uccuuauuca gggucaucua auuucacaug guuaguuuau     2520

aaagagggag acgaucaaaa ccauauugca agugguauag auaagaauaa cucaaaaguu     2580

ggaacauuua aaucuacaaa aggaagacau uauguguuua uauauaaaca cgauucugcu     2640

ucaaauauau ccuauucuuu aaacauaaaa ggauuaggua acgagaaauu gaaggaaaaa     2700

gaaaauaaug auucuucuga uaaagcuaca guuauaccaa auuucaauac cacuaugcaa     2760

gguucacuuu uaggugauga uucaagagau uauuauucuu uugagguuaa ggaagaaggc     2820

gaaguuaaua uagaacuaga uaaaaaggau gaauuuggug uaacauggac acuacaucca     2880

gagucaaaua uuaaugacag aauaacuuac ggacaaguug augguaauaa gguaucuaau     2940

aaaguuaaau uaagaccagg aaaauauuau cuacuuguuu auaaauacuc aggaucagga     3000

aacuaugagu uaaggguaaa uaaauaa                                         3027


<210>  5198
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5198
augaaaaaaa auauuuuaaa gauucuuaug gauaguuauu cuaaagaauc uaaaauucaa       60

acuguacgua ggguuacgag uguaucacuu uuagcgguau aucuuacuau gaauacuuca      120

aguuuaguuu uagcaaaacc aauagaaaau acuaaugaua cuaguauaaa aaauguggag      180

aaauuaagaa augcuccaaa ugaagagaau aguaaaaagg uagaagauag uaaaaaugau      240

aagguagaac augugaaaaa uauagaagag gcaaagguug agcaaguugc acccgaagua      300

aaaucuaaau caacuuuaag aagugcuucu agaaggcggc gcaagagaau agcgaauacu      360

aauucugaga aauaugauuu ugaguauuua aaugguuuga gcuauacuga acuuacaaau      420

uuaauuaaaa auauaaagug gaaucaaauu aaugguuuau uuaauuauag uacagguucu      480

caaaaguucu uuggagauaa aaaucgugua caagcuauaa uuaaugcuuu acaagaaagu      540

ggaagaacuu acacugcaaa ugauaugaag gguauagaaa cuuucacuga gguuuuaaga      600

gcugguuuuu auuuagggua cuauaaugau gguuuaucuu auuuaaauga uagaaacuuc      660

caagauaaau guauaccugc aaugauugca auucaaaaaa auccuaacuu uaagcuagga      720

acugcaguuc aagaugaagu uauaacuucu uuaggaaaac uaauaggaaa ugcuucugcu      780

aaugcugaag uaguuaauaa uuguguacca guucuaaaac aauuuagaga aaacuuaaau      840

caauaugcuc cugauuacgu uaaaggaaca gcuguaaaug aauuaauuaa agguauugaa      900

uucgauuuuu cuggugcugc auaugaaaaa gauguuaaga caaugccuug guauggaaaa      960

auugauccau uuauaaauga acuuaaggcc uuaggucuau auggaaauau aacaagugca     1020

acugaguggg caucugaugu uggaauauac uauuuaagua aauucggucu uuacucaacu     1080

aaccgaaaug acauaguaca gucacuugaa aaggcuguag auauguauaa guaugguaaa     1140

auagccuuug uagcaaugga gagaauaacu ugggauuaug augggauugg uucuaauggu     1200

aaaaaggugg aucacgauaa guucuuagau gaugcugaaa aacauuaucu gccaaagaca     1260

uauacuuuug auaauggaac cuuuauuaua agagcagggg auaagguauc cgaagaaaaa     1320

auaaaaaggc uauauugggc aucaagagaa gugaagucuc aauuccauag aguaguuggc     1380

aaugauaaag cuuuagaggu gggaaaugcc gaugauguuu uaacuaugaa aauauuuaau     1440

agcccagaag aauauaaauu uaauaccaau auaaauggug uaagcacuga uaaugguggu     1500

cuauauauag aaccaagagg gacuuucuac acuuaugaga gaacaccuca acaaaguaua     1560

uuuagucuug aagaauuguu uagacaugaa uauacucacu auuuacaagc gagauaucuu     1620

guagaugguu uaugggggca agguccauuu uaugaaaaaa auagauuaac uugguuugau     1680

gaagguacag cugaauucuu ugcaggaucu acccguacau cugguguuuu accaagaaaa     1740

ucaauauuag gauauuuggc uaaggauaaa guagaucaua gauacucauu aaagaagacu     1800

cuuaauucag gguaugauga cagugauugg auguucuaua auuauggauu ugcaguugca     1860

cauuaccuau augaaaaaga uaugccuaca uuuauuaaga ugaauaaagc uauauugaau     1920

acagauguga aaucuuauga ugaaauaaua aaaaaauuaa gugaugaugc aaauaaaaau     1980

acagaauauc aaaaccauau ucaagaguua gcagauaaau aucaaggagc aggcauaccu     2040

cuaguaucag augauuacuu aaaagaucau ggauauaaga aagcaucuga aguauauucu     2100

gaaauuucaa aagcugcuuc ucuuacaaac acuaguguaa cagcagaaaa aucucaauau     2160

uuuaacacau ucacuuuaag aggaacuuau acaggugaaa cuucuaaagg ugaauuuaaa     2220

gauugggaug aaaugaguaa aaaauuagau ggaacuuugg agucccuugc uaaaaauucu     2280

uggaguggau acaaaacuuu aacagcauac uuuacgaauu auagaguuac aagcgauaau     2340

aaaguucaau augauguagu uuuccauggg guuuuaacag auaaugcgga uauuaguaac     2400

aauaaggcuc caauagcaaa gguaacugga ccaagcacug gugcuguagg aagaaauauu     2460

gaauuuagug gaaaagauag uaaagaugaa gaugguaaaa uaguaucaua ugauugggau     2520

uuuggcgaug gugcaacuag uagaggcaaa aauucaguac augcuuacaa aaaagcagga     2580

acauauaaug uuacauuaaa aguaacugac gauaagggug caacagcuac agaaagcuuu     2640

acuauagaaa uaaagaacga agauacaaca acaccuauaa cuaaagaaau ggaaccuaau     2700

gaugauauaa aagaggcuaa ugguccaaua guugaaggug uuacuguaaa aggugauuua     2760

aaugguucug augaugcuga uaccuucuau uuugauguaa aagaagaugg ugauguuaca     2820

auugaacuuc cuuauucagg gucaucuaau uucacauggu uaguuuauaa agagggagac     2880

gaucaaaacc auauugcaag ugguauagau aagaauaacu caaaaguugg aacauuuaaa     2940

ucuacaaaag gaagacauua uguguuuaua uauaaacacg auucugcuuc aaauauaucc     3000

uauucuuuaa acauaaaagg auuagguaac gagaaauuga aggaaaaaga aaauaaugau     3060

ucuucugaua aagcuacagu uauaccaaau uucaauacca cuaugcaagg uucacuuuua     3120

ggugaugauu caagagauua uuauucuuuu gagguuaagg aagaaggcga aguuaauaua     3180

gaacuagaua aaaaggauga auuuggugua acauggacac uacauccaga gucaaauauu     3240

aaugacagaa uaacuuacgg acaaguugau gguaauaagg uaucuaauaa aguuaaauua     3300

agaccaggaa aauauuaucu acuuguuuau aaauacucag gaucaggaaa cuaugaguua     3360

aggguaaaua aauaa                                                      3375


<210>  5199
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5199
augaaaaaaa auauuuuaaa gauucuuaug gauaguuauu cuaaagaauc uaaaauucaa       60

acuguacgua ggguuacgag uguaucacuu uuagcgguau aucuuacuau gaauacuuca      120

aguuuaguuu uagcaaaacc aauagaaaau acuaaugaua caaguauaaa aaauguggag      180

aaauuaagaa augcuccaaa ugaagagaau aguaaaaagg uagaagauag uaaaaaugau      240

aagguagaac augugaaaaa uauagaagag gcaaagguug agcaaguugc acccgaagua      300

aaaucuaaau caacuuuaag aagugcuucu agaaggcggc gcaagagaau agcgaauacu      360

aauucugaga aauaugauuu ugaguauuua aaugguuuga gcuauacuga acuuacaaau      420

uuaauuaaaa auauaaagug gaaucaaauu aaugguuuau uuaauuauag uacagguucu      480

caaaaguucu uuggagauaa aaaucgugua caagcuauaa uuaaugcuuu acaagaaagu      540

ggaagaacuu acacugcaaa ugauaugaag gguauagaaa cuuucacuga gguuuuaaga      600

gcugguuuuu auuuagggua cuauaaugau gguuuaucuu auuuaaauga uagaaacuuc      660

caagauaaau guauaccugc aaugauugca auucaaaaaa auccuaacuu uaagcuagga      720

acugcaguuc aagaugaagu uauaacuucu uuaggaaaac uaauaggaaa ugcuucugcu      780

aaugcugaag uaguuaauaa uuguguacca guucuaaaac aauuuagaga aaacuuaaau      840

caauaugcuc cugauuacgu uaaaggaaca gcuguaaaug aauuaauuaa agguauugag      900

uucgauuuuu cuggugcugc auaugaaaaa gauguuaaga caaugccuug guauggaaaa      960

auugauccau uuauaaauga acuuaaggcc uuaggucuau auggaaauau aacaagugca     1020

acugaguggg caucugaugu uggaauauac uauuuaagua aauucggucu uuacucaacu     1080

aaccgaaaug acauaguaca gucacuugaa aaggcuguag auauguauaa guaugguaaa     1140

auagccuuug uagcaaugga gagaauaacu ugggauuaug augggauugg uucuaauggu     1200

aaaaaggugg aucacgauaa guucuuagau gaugcugaaa aacauuaucu gccaaagaca     1260

uauacuuuug auaauggaac cuuuauuaua agagcagggg auaagguauc cgaagaaaaa     1320

auaaaaaggc uauauugggc aucaagagaa gugaagucuc aauuccauag aguaguuggc     1380

aaugauaaag cauuagaggu gggaaaugcc gaugauguuu uaacuaugaa aauauuuaau     1440

agcccagaag aauauaaauu uaauaccaau auaaauggug uaagcacuga uaaugguggu     1500

cuauauauag aaccaagagg gacuuucuac acuuaugaga gaacaccuca acaaaguaua     1560

uuuagucuug aagaauuguu uagacaugaa uauacucacu auuuacaagc gagauaucuu     1620

guagaugguu uaugggggca agguccauuu uaugaaaaaa auagauuaac uugguuugau     1680

gaagguacag cugaguucuu ugcaggaucu acccguacau cugguguuuu accaagaaaa     1740

ucaauauuag gauauuuggc uaaggauaaa guagaucaua gauacucauu aaagaagacu     1800

cuuaauucag gguaugauga cagugauugg auguucuaua auuauggauu ugcaguugca     1860

cauuaccuau augaaaaaga uaugccuaca uuuauuaaga ugaauaaagc uauauugaau     1920

acagauguga aaucuuauga ugaaauaaua aaaaaauuaa gugaugaugc aaauaaaaau     1980

acagaauauc aaaaccauau ucaagaguua gcagauaaau aucaaggagc aggcauaccu     2040

cuaguaucag augauuacuu aaaagaucau ggauauaaga aagcaucuga aguauauucu     2100

gaaauuucaa aagcugcuuc ucuuacaaac acaaguguaa cagcagaaaa aucucaauau     2160

uuuaacacau ucacuuuaag aggaacuuau acaggugaaa cuucuaaagg ugaauuuaaa     2220

gauugggaug aaaugaguaa aaaauuagau ggaacuuugg agucccuugc uaaaaauucu     2280

uggaguggau acaaaacuuu aacagcauac uuuacgaauu auagaguuac aagcgauaau     2340

aaaguucaau augauguagu uuuccauggg guuuuaacag auaaugcgga uauuaguaac     2400

aauaaggcuc caauagcaaa gguaacugga ccaagcacug gugcuguagg aagaaauauu     2460

gaauuuagug gaaaagauag uaaagaugaa gaugguaaaa uaguaucaua ugauugggau     2520

uuuggcgaug gugcaacaag uagaggcaaa aauucaguac augcuuacaa aaaagcagga     2580

acauauaaug uuacauuaaa aguaacugac gauaagggug caacagcuac agagagcuuu     2640

acuauagaaa uaaagaacga agauacaaca acaccuauaa cuaaagaaau ggaaccuaau     2700

gaugauauaa aagaggcuaa ugguccaaua guugaaggug uuacuguaaa aggugauuua     2760

aaugguucug augaugcuga uaccuucuau uuugauguaa aagaagaugg ugauguuaca     2820

auugaacuuc cuuauucagg gucaucuaau uucacauggu uaguuuauaa agagggagac     2880

gaucaaaacc auauugcaag ugguauagau aagaauaacu caaaaguugg aacauuuaaa     2940

ucuacaaaag gaagacauua uguguuuaua uauaaacacg auucugcuuc aaauauaucc     3000

uauucuuuaa acauaaaagg auuagguaac gagaaauuga aggaaaaaga aaauaaugau     3060

ucuucugaua aagcuacagu uauaccaaau uucaauacca cuaugcaagg uucacuuuua     3120

ggugaugauu caagagauua uuauucuuuu gagguuaagg aagaaggcga aguuaauaua     3180

gaacuagaua aaaaggauga auuuggugua acauggacac uacauccaga gucaaauauu     3240

aaugacagaa uaacuuacgg acaaguugau gguaauaagg uaucuaauaa aguuaaauua     3300

agaccaggaa aauauuaucu acuuguuuau aaauacucag gaucaggaaa cuaugaguua     3360

aggguaaaua aauaa                                                      3375


<210>  5200
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5200
guacaaaaug aaaguaagag guauacagua ucauauuuaa agacuuuaaa uuauuaugac       60

uuaguagauu ugcuuguuaa gacugaaauu gagaauuuac cagaccuuuu ucaguauagu      120

ucagaugcaa aagaguucua uggaaauaaa acucguauga gcuuuaucau ggaugaaauu      180

gguagaaggg caccucagua uacagagaua gaucauaaag guauuccuac uuuaguagaa      240

guuguaagag cuggauuuua cuuaggauuc cauaacaagg aauugaauga aauaaacaag      300

aggucuuuua aagaaagggu aauaccuucu auauuagcaa uucaaaaaaa uccuaauuuu      360

aaacuaggua cugaaguuca agauaaaaua guaucugcaa caggacuuuu agcugguaau      420

gaaacagcgc cuccagaagu uguaaauaau uuuacaccaa uacuucaaga cuguauaaag      480

aauauagaca gauacgcucu ugaugauuua aagucaaaag cauuauuuaa uguuuuagcu      540

gcaccuaccu augauauaac ugaguauuua agagcuacua aagaaaaacc agaaaacacu      600

ccuugguaug guaaaauaga uggguuuaua aaugaacuua aaaaguuagc ucuuuaugga      660

aaaauaaaug auaauaacuc uuggauaaua gauaacggua uauaucauau agcaccuuua      720

gggaaguuac auagcaauaa uaaaauagga auagaaacuu uaacagaggu uaugaaaguu      780

uauccuuauu uaaguaugca acauuuacaa ucagcagauc aaauuaagcg ucauuaugau      840

ucaaaagaug cugaaggaaa caaaauaccu uuagauaagu uuaaaaagga aggaaaagaa      900

aaauacuguc caaaaacuua uacauuugau gauggaaaag uaauaauaaa agcuggugcu      960

agaguagaag aagaaaaagu uaaaagacua uacugggcau caaaggaagu uaacucucaa     1020

uucuuuagag uauacggaau agacaaacca uuagaagaag guaauccaga ugauauauua     1080

acaaugguua ucuacaacag ucccgaagaa uauaaacuca auaguguucu auacggauau     1140

gauacuaaua auggugguau guauauagag ccagaaggaa cuuucuucac cuaugaaaga     1200

gaagcucaag aaagcacaua cacauuagaa gaauuauuua gacaugaaua uacacauuau     1260

uugcaaggaa gauaugcagu uccaggacaa uggggaagaa caaaacuuua ugacaaugau     1320

agauuaacuu gguaugaaga agguggagca gaauuauuug cagguucuac uagaacuucu     1380

ggaauauuac caagaaagag uauaguauca aauauucaua auacaacaag aaauaauaga     1440

uauaagcuuu cagacacugu acauucuaaa uauggugcua guuuugaauu cuauaauuau     1500

gcauguaugu uuauggauua uauguauaau aaagauaugg guauauuaaa uaaacuaaau     1560

gaucuugcaa aaaauaauga uguugaugga uaugauaauu auauuagaga uuuaaguucu     1620

aauuaugcuu uaaaugauaa auaucaagau cauaugcagg agcgcauaga uaauuaugaa     1680

aauuuaacag ugccuuuugu agcugaugau uauuuaguaa ggcaugcuua uaagaacccu     1740

aaugaaauuu auucugaaau aucugaagua gcaaaauuaa aggaugcuaa gagugaaguu     1800

aagaaaucac aauauuuuag uaccuuuacu uugagaggua guuacacagg uggagcaucu     1860

aaggggaaau uagaagauca aaaagcaaug aauaaguuua uagaugauuc acuuaagaaa     1920

uuagauacgu auucuuggag uggguauaaa acuuuaacug cuuauuucac uaauuauaaa     1980

guugacucuu caaauagagu uacuuaugau guaguauucc acggauauuu accaaacgaa     2040

ggugauucca aaaauucauu accuuauggc aagaucaaug gaacuuacaa gggaacagag     2100

aaagaaaaaa ucaaauucuc uagugaaggc ucuuucgauc cagaugguaa aauaguuucu     2160

uaugaauggg auuucggaga ugguaauaag aguaaugagg aaaauccaga gcauucauau     2220

gacaagguag gaacuuauac agugaaauua aaaguuacug augacaaggg agaaucuuca     2280

guaucuacua cuacugcaga aauaaaggau cuuucagaaa auaaacuucc aguuauauau     2340

augcauguac cuaaauccgg agccuuaaau caaaaaguug uuuucuaugg aaaaggaaca     2400

uaugacccag auggaucuau cgcaggauau caaugggacu uuggugaugg aagugauuuu     2460

agcagugaac aaaacccaag ccauguauau acuaaaaaag gugaauauac uguaacauua     2520

agaguaaugg auaguagugg acaaaugagu gaaaaaacua ugaagauuaa gauuacagau     2580

ccgguauauc caauaggcac ugaaaaagaa ccaaauaaca guaaagaaac ugcaaguggu     2640

ccaauaguac cagguauacc uguuagugga accauagaaa auacaaguga ucaagauuau     2700

uucuauuuug auguuauaac accaggagaa guaaaaauag auauaaauaa auuaggguac     2760

ggaggagcua cuuggguagu auaugaugaa aauaauaaug caguaucuua ugccacugau     2820

gaugggcaaa auuuaagugg aaaguuuaag gcagauaaac cagguagaua uuacauccau     2880

cuuuacaugu uuaaugguag uuauaugcca uauagaauua auauagaagg uucaguagga     2940

agauaa                                                                2946


<210>  5201
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5201
guacaaaaug aaaguaagag guauacagua ucauauuuaa agacuuuaaa uuauuaugac       60

uuaguagauu ugcuuguuaa gacugaaauu gagaauuuac cagaccuuuu ucaguauagu      120

ucagaugcaa aagaguucua uggaaauaaa acucguauga gcuuuaucau ggaugaaauu      180

gguagaaggg caccucagua uacagagaua gaucauaaag guauuccuac uuuaguagaa      240

guuguaagag cuggauuuua cuuaggauuc cauaacaagg aauugaauga aauaaacaag      300

aggucuuuua aagaaagggu aauaccuucu auauuagcaa uucaaaaaaa uccuaauuuu      360

aaacuaggua cugaaguuca agauaaaaua guaucugcaa caggacuuuu agcugguaau      420

gaaacagcgc cuccagaagu uguaaauaau uuuacaccaa uacuucaaga cuguauaaag      480

aauauagaca gauacgcucu ugaugauuua aagucaaaag cauuauuuaa uguuuuagcu      540

gcaccuaccu augauauaac ugaguauuua agagcuacua aagaaaaacc agaaaacacu      600

ccuugguaug guaaaauaga uggguuuaua aaugaacuua aaaaguuagc ucuuuaugga      660

aaaauaaaug auaauaacuc uuggauaaua gauaacggua uauaucauau agcaccuuua      720

gggaaguuac auagcaauaa uaaaauagga auagaaacuu uaacagaggu uaugaaaguu      780

uauccuuauu uaaguaugca acauuuacaa ucagcagauc aaauuaagcg ucauuaugau      840

ucaaaagaug cugaaggaaa caaaauaccu uuagauaagu uuaaaaagga aggaaaagaa      900

aaauacuguc caaaaacuua uacauuugau gauggaaaag uaauaauaaa agcuggugcu      960

agaguagaag aagaaaaagu uaaaagacua uacugggcau caaaggaagu uaacucucaa     1020

uucuuuagag uauacggaau agacaaacca uuagaagaag guaauccaga ugauauauua     1080

acaaugguua ucuacaacag ucccgaagaa uauaaacuca auaguguucu auacggauau     1140

gauacuaaua auggugguau guauauagag ccagaaggaa cuuucuucac cuaugaaaga     1200

gaagcucaag aaagcacaua cacauuagaa gaauuauuua gacaugaaua uacacauuau     1260

uugcaaggaa gauaugcagu uccaggacaa uggggaagaa caaaacuuua ugacaaugau     1320

agauuaacuu gguaugaaga agguggagca gaauuauuug cagguucuac uagaacuucu     1380

ggaauauuac caagaaagag uauaguauca aauauucaua auacaacaag aaauaauaga     1440

uauaagcugu cagacacugu acauucuaaa uauggugcua guuuugaguu cuauaauuau     1500

gcauguaugu uuauggauua uauguauaau aaagauaugg guauauuaaa uaaacuaaau     1560

gaucuugcaa aaaauaauga uguugaugga uaugauaauu auauuagaga uuuaaguucu     1620

aauuaugcuu uaaaugauaa auaucaagau cauaugcagg agcgcauaga uaauuaugaa     1680

aauuuaacag ugccuuuugu agcugaugau uauuuaguaa ggcaugcuua uaagaacccu     1740

aaugaaauuu auucugaaau aucugaagua gcaaaauuaa aggaugcuaa gagugaaguu     1800

aagaaaucac aauauuuuag uaccuuuacu uugagaggua guuacacagg uggagcaucu     1860

aaggggaaau uagaagauca aaaagcaaug aauaaguuua uagaugauuc acuuaagaaa     1920

uuagauacgu auucuuggag uggguauaaa acuuuaacug cuuauuucac uaauuauaaa     1980

guugacucuu caaauagagu uacuuaugau guaguauucc acggauauuu accaaacgaa     2040

ggugauucca aaaauucauu accuuauggc aagaucaaug gaacuuacaa gggaacagag     2100

aaagaaaaaa ucaaauucuc uagugaaggc ucuuucgauc cagaugguaa aauaguuucu     2160

uaugaauggg auuucggaga ugguaauaag aguaaugagg aaaauccaga gcauucauau     2220

gacaagguag gaacuuauac agugaaauua aaaguuacug augacaaggg agaaucuuca     2280

guaucuacua cuacugcaga aauaaaggau cuuucagaaa auaaacuucc aguuauauau     2340

augcauguac cuaaauccgg agccuuaaau caaaaaguug uuuucuaugg aaaaggaaca     2400

uaugacccag auggaucuau cgcaggauau caaugggacu uuggugaugg aagugauuuu     2460

agcagugaac aaaacccaag ccauguauau acuaaaaaag gugaauauac uguaacauua     2520

agaguaaugg auaguagugg acaaaugagu gaaaaaacua ugaagauuaa gauuacagau     2580

ccgguauauc caauaggcac ugaaaaagaa ccaaauaaca guaaagaaac ugcaaguggu     2640

ccaauaguac cagguauacc uguuagugga accauagaaa auacaaguga ucaagauuau     2700

uucuauuuug auguuauaac accaggagaa guaaaaauag auauaaauaa auuaggguac     2760

ggaggagcua cuuggguagu auaugaugaa aauaauaaug caguaucuua ugccacugau     2820

gaugggcaaa auuuaagugg aaaguuuaag gcagauaaac cagguagaua uuacauccau     2880

cuuuacaugu uuaaugguag uuauaugcca uauagaauua auauagaagg uucaguagga     2940

agauaa                                                                2946


<210>  5202
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5202
augaaaagga aauguuuauc uaaaaggcuu auguuagcua uaacaauggc uacaauauuu       60

acagugaaca guacauuacc aauuuaugca gcuguagaua aaaauaaugc aacagcagcu      120

agaaggcggc gcaagagagu acaaaaugaa aguaagaggu auacaguauc auauuuaaag      180

acuuuaaauu auuaugacuu aguagauuug cuuguuaaga cugaaauuga gaauuuacca      240

gaccuuuuuc aguauaguuc agaugcaaaa gaguucuaug gaaauaaaac ucguaugagc      300

uuuaucaugg augaaauugg uagaagggca ccucaguaua cagagauaga ucauaaaggu      360

auuccuacuu uaguagaagu uguaagagcu ggauuuuacu uaggauucca uaacaaggaa      420

uugaaugaaa uaaacaagag gucuuuuaaa gaaaggguaa uaccuucuau auuagcaauu      480

caaaaaaauc cuaauuuuaa acuagguacu gaaguucaag auaaaauagu aucugcaaca      540

ggacuuuuag cugguaauga aacagcgccu ccagaaguug uaaauaauuu uacaccaaua      600

cuucaagacu guauaaagaa uauagacaga uacgcucuug augauuuaaa gucaaaagca      660

uuauuuaaug uuuuagcugc accuaccuau gauauaacug aguauuuaag agcuacuaaa      720

gaaaaaccag aaaacacucc uugguauggu aaaauagaug gguuuauaaa ugaacuuaaa      780

aaguuagcuc uuuauggaaa aauaaaugau aauaacucuu ggauaauaga uaacgguaua      840

uaucauauag caccuuuagg gaaguuacau agcaauaaua aaauaggaau agaaacuuua      900

acagagguua ugaaaguuua uccuuauuua aguaugcaac auuuacaauc agcagaucaa      960

auuaagcguc auuaugauuc aaaagaugcu gaaggaaaca aaauaccuuu agauaaguuu     1020

aaaaaggaag gaaaagaaaa auacugucca aaaacuuaua cauuugauga uggaaaagua     1080

auaauaaaag cuggugcuag aguagaagaa gaaaaaguua aaagacuaua cugggcauca     1140

aaggaaguua acucucaauu cuuuagagua uacggaauag acaaaccauu agaagaaggu     1200

aauccagaug auauauuaac aaugguuauc uacaacaguc ccgaagaaua uaaacucaau     1260

aguguucuau acggauauga uacuaauaau ggugguaugu auauagagcc agaaggaacu     1320

uucuucaccu augaaagaga agcucaagaa agcacauaca cauuagaaga auuauuuaga     1380

caugaauaua cacauuauuu gcaaggaaga uaugcaguuc caggacaaug gggaagaaca     1440

aaacuuuaug acaaugauag auuaacuugg uaugaagaag guggagcaga auuauuugca     1500

gguucuacua gaacuucugg aauauuacca agaaagagua uaguaucaaa uauucauaau     1560

acaacaagaa auaauagaua uaagcuuuca gacacuguac auucuaaaua uggugcuagu     1620

uuugaauucu auaauuaugc auguauguuu auggauuaua uguauaauaa agauaugggu     1680

auauuaaaua aacuaaauga ucuugcaaaa aauaaugaug uugauggaua ugauaauuau     1740

auuagagauu uaaguucuaa uuaugcuuua aaugauaaau aucaagauca uaugcaggag     1800

cgcauagaua auuaugaaaa uuuaacagug ccuuuuguag cugaugauua uuuaguaagg     1860

caugcuuaua agaacccuaa ugaaauuuau ucugaaauau cugaaguagc aaaauuaaag     1920

gaugcuaaga gugaaguuaa gaaaucacaa uauuuuagua ccuuuacuuu gagagguagu     1980

uacacaggug gagcaucuaa ggggaaauua gaagaucaaa aagcaaugaa uaaguuuaua     2040

gaugauucac uuaagaaauu agauacguau ucuuggagug gguauaaaac uuuaacugcu     2100

uauuucacua auuauaaagu ugacucuuca aauagaguua cuuaugaugu aguauuccac     2160

ggauauuuac caaacgaagg ugauuccaaa aauucauuac cuuauggcaa gaucaaugga     2220

acuuacaagg gaacagagaa agaaaaaauc aaauucucua gugaaggcuc uuucgaucca     2280

gaugguaaaa uaguuucuua ugaaugggau uucggagaug guaauaagag uaaugaggaa     2340

aauccagagc auucauauga caagguagga acuuauacag ugaaauuaaa aguuacugau     2400

gacaagggag aaucuucagu aucuacuacu acugcagaaa uaaaggaucu uucagaaaau     2460

aaacuuccag uuauauauau gcauguaccu aaauccggag ccuuaaauca aaaaguuguu     2520

uucuauggaa aaggaacaua ugacccagau ggaucuaucg caggauauca augggacuuu     2580

ggugauggaa gugauuuuag cagugaacaa aacccaagcc auguauauac uaaaaaaggu     2640

gaauauacug uaacauuaag aguaauggau aguaguggac aaaugaguga aaaaacuaug     2700

aagauuaaga uuacagaucc gguauaucca auaggcacug aaaaagaacc aaauaacagu     2760

aaagaaacug caaguggucc aauaguacca gguauaccug uuaguggaac cauagaaaau     2820

acaagugauc aagauuauuu cuauuuugau guuauaacac caggagaagu aaaaauagau     2880

auaaauaaau uaggguacgg aggagcuacu uggguaguau augaugaaaa uaauaaugca     2940

guaucuuaug ccacugauga ugggcaaaau uuaaguggaa aguuuaaggc agauaaacca     3000

gguagauauu acauccaucu uuacauguuu aaugguaguu auaugccaua uagaauuaau     3060

auagaagguu caguaggaag auaa                                            3084


<210>  5203
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5203
augaaaagga aauguuuauc uaaaaggcuu auguuagcua uaacaauggc uacaauauuu       60

acagugaaca guacauuacc aauuuaugca gcuguagaua aaaauaaugc aacagcagcu      120

agaaggcggc gcaagagagu acaaaaugaa aguaagaggu auacaguauc auauuuaaag      180

acuuuaaauu auuaugacuu aguagauuug cuuguuaaga cugaaauuga gaauuuacca      240

gaccuuuuuc aguauaguuc agaugcaaaa gaguucuaug gaaauaaaac ucguaugagc      300

uuuaucaugg augaaauugg uagaagggca ccucaguaua cagagauaga ucauaaaggu      360

auuccuacuu uaguagaagu uguaagagcu ggauuuuacu uaggauucca uaacaaggaa      420

uugaaugaaa uaaacaagag gucuuuuaaa gaaaggguaa uaccuucuau auuagcaauu      480

caaaaaaauc cuaauuuuaa acuagguacu gaaguucaag auaaaauagu aucugcaaca      540

ggacuuuuag cugguaauga aacagcgccu ccagaaguug uaaauaauuu uacaccaaua      600

cuucaagacu guauaaagaa uauagacaga uacgcucuug augauuuaaa gucaaaagca      660

uuauuuaaug uuuuagcugc accuaccuau gauauaacug aguauuuaag agcuacuaaa      720

gaaaaaccag aaaacacucc uugguauggu aaaauagaug gguuuauaaa ugaacuuaaa      780

aaguuagcuc uuuauggaaa aauaaaugau aauaacucuu ggauaauaga uaacgguaua      840

uaucauauag caccuuuagg gaaguuacau agcaauaaua aaauaggaau agaaacuuua      900

acagagguua ugaaaguuua uccuuauuua aguaugcaac auuuacaauc agcagaucaa      960

auuaagcguc auuaugauuc aaaagaugcu gaaggaaaca aaauaccuuu agauaaguuu     1020

aaaaaggaag gaaaagaaaa auacugucca aaaacuuaua cauuugauga uggaaaagua     1080

auaauaaaag cuggugcuag aguagaagaa gaaaaaguua aaagacuaua cugggcauca     1140

aaggaaguua acucucaauu cuuuagagua uacggaauag acaaaccauu agaagaaggu     1200

aauccagaug auauauuaac aaugguuauc uacaacaguc ccgaagaaua uaaacucaau     1260

aguguucuau acggauauga uacuaauaau ggugguaugu auauagagcc agaaggaacu     1320

uucuucaccu augaaagaga agcucaagaa agcacauaca cauuagaaga auuauuuaga     1380

caugaauaua cacauuauuu gcaaggaaga uaugcaguuc caggacaaug gggaagaaca     1440

aaacuuuaug acaaugauag auuaacuugg uaugaagaag guggagcaga auuauuugca     1500

gguucuacua gaacuucugg aauauuacca agaaagagua uaguaucaaa uauucauaau     1560

acaacaagaa auaauagaua uaagcuguca gacacuguac auucuaaaua uggugcuagu     1620

uuugaguucu auaauuaugc auguauguuu auggauuaua uguauaauaa agauaugggu     1680

auauuaaaua aacuaaauga ucuugcaaaa aauaaugaug uugauggaua ugauaauuau     1740

auuagagauu uaaguucuaa uuaugcuuua aaugauaaau aucaagauca uaugcaggag     1800

cgcauagaua auuaugaaaa uuuaacagug ccuuuuguag cugaugauua uuuaguaagg     1860

caugcuuaua agaacccuaa ugaaauuuau ucugaaauau cugaaguagc aaaauuaaag     1920

gaugcuaaga gugaaguuaa gaaaucacaa uauuuuagua ccuuuacuuu gagagguagu     1980

uacacaggug gagcaucuaa ggggaaauua gaagaucaaa aagcaaugaa uaaguuuaua     2040

gaugauucac uuaagaaauu agauacguau ucuuggagug gguauaaaac uuuaacugcu     2100

uauuucacua auuauaaagu ugacucuuca aauagaguua cuuaugaugu aguauuccac     2160

ggauauuuac caaacgaagg ugauuccaaa aauucauuac cuuauggcaa gaucaaugga     2220

acuuacaagg gaacagagaa agaaaaaauc aaauucucua gugaaggcuc uuucgaucca     2280

gaugguaaaa uaguuucuua ugaaugggau uucggagaug guaauaagag uaaugaggaa     2340

aauccagagc auucauauga caagguagga acuuauacag ugaaauuaaa aguuacugau     2400

gacaagggag aaucuucagu aucuacuacu acugcagaaa uaaaggaucu uucagaaaau     2460

aaacuuccag uuauauauau gcauguaccu aaauccggag ccuuaaauca aaaaguuguu     2520

uucuauggaa aaggaacaua ugacccagau ggaucuaucg caggauauca augggacuuu     2580

ggugauggaa gugauuuuag cagugaacaa aacccaagcc auguauauac uaaaaaaggu     2640

gaauauacug uaacauuaag aguaauggau aguaguggac aaaugaguga aaaaacuaug     2700

aagauuaaga uuacagaucc gguauaucca auaggcacug aaaaagaacc aaauaacagu     2760

aaagaaacug caaguggucc aauaguacca gguauaccug uuaguggaac cauagaaaau     2820

acaagugauc aagauuauuu cuauuuugau guuauaacac caggagaagu aaaaauagau     2880

auaaauaaau uaggguacgg aggagcuacu uggguaguau augaugaaaa uaauaaugca     2940

guaucuuaug ccacugauga ugggcaaaau uuaaguggaa aguuuaaggc agauaaacca     3000

gguagauauu acauccaucu uuacauguuu aaugguaguu auaugccaua uagaauuaau     3060

auagaagguu caguaggaag auaa                                            3084


<210>  5204
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5204
aucgccaaca ccaacagcga gaaguacgac uucgaguacc ugaacggccu cuccuacacc       60

gagcugacca accugaucaa gaacaucaag uggaaccaga ucaacgggcu cuucaacuac      120

agcacgggcu cccagaaguu cuucggggac aagaaccgcg ugcaggcgau caucaacgcc      180

cugcaggaga gcggccggac cuacaccgcc aacgacauga aggggaucga gaccuucacg      240

gagguccugc gcgccggcuu cuaccucggc uacuacaacg acgggcuguc cuaccugaac      300

gaccggaacu uccaggacaa gugcaucccc gcgaugaucg ccauccagaa gaaccccaac      360

uucaagcucg gcaccgccgu gcaggacgag gugaucacca gccuggggaa gcugaucggc      420

aacgccagcg ccaacgcgga ggucgugaac aacugcgugc cgguccucaa gcaguuccgc      480

gagaaccuga accaguacgc ccccgacuac gugaagggga ccgccgugaa cgagcugauc      540

aagggcaucg aguucgacuu cuccggcgcc gccuacgaga aggacgucaa gacgaugccc      600

ugguacggga agaucgaccc cuucaucaac gagcucaagg cgcugggccu guacgggaac      660

aucaccagcg ccaccgagug ggccuccgac gugggcaucu acuaccucag caaguucggc      720

cuguacucca ccaaccggaa cgacaucgug cagagccugg agaaggccgu cgacauguac      780

aaguacggga agaucgccuu cguggcgaug gagcgcauca cgugggacua cgacggcauc      840

ggguccaacg gcaagaaggu cgaccacgac aaguuccucg acgacgccga gaagcacuac      900

cugccgaaga ccuacaccuu cgacaacggg accuucauca uccgggccgg cgacaaggug      960

agcgaggaga agaucaagcg ccuguacugg gccucccggg aggugaagag ccaguuccac     1020

cgcgucgugg gcaacgacaa ggcccucgag guggggaacg cggacgacgu ccugacgaug     1080

aagaucuuca acucccccga ggaguacaag uucaacacca acaucaacgg cgugagcacc     1140

gacaacgggg gccuguacau cgagccgcgg gggaccuucu acacguacga gcgcaccccg     1200

cagcagucca ucuucagccu cgaggagcug uuccggcacg aguacaccca cuaccugcag     1260

gcccgcuacc ucguggacgg ccuguggggc caggggccgu ucuacgagaa gaaccggcug     1320

accugguucg acgagggcac ggccgaguuc uucgccgggu ccacccgcac cagcggcguc     1380

cucccccgga aguccauccu gggguaccug gcgaaggaca agguggacca ccgcuacagc     1440

cucaagaaga cccugaacuc cggcuacgac gacagcgacu ggauguucua caacuacggc     1500

uucgccgugg cccacuaccu guacgagaag gacaugccca cguucaucaa gaugaacaag     1560

gccauccuga acaccgacgu caagagcuac gacgagauca ucaagaagcu cuccgacgac     1620

gccaacaaga acaccgagua ccagaaccac auccaggagc uggcggacaa guaccagggg     1680

gccggcaucc cccuggugag cgacgacuac cucaaggacc acggguacaa gaaggccucc     1740

gagguguaca gcgagaucuc caaggccgcc agccugacca acaccuccgu cacggcggag     1800

aagagccagu acuucaacac cuucacccug cgcggcaccu acacgggcga gaccuccaag     1860

ggggaguuca aggacuggga cgagaugagc aagaagcucg acggcacccu ggagucccug     1920

gccaagaaca gcugguccgg guacaagacc cucacggccu acuucaccaa cuaccgggug     1980

accagcgaca acaaggugca guacgacguc guguuccacg gcgugcugac cgacaacgcc     2040

gacaucucca acaacaaggc cccgaucgcg aaggucacgg ggcccagcac cggcgccgug     2100

ggccgcaaca ucgaguucuc cgggaaggac agcaaggacg aggacggcaa gaucgugagc     2160

uacgacuggg acuucgggga cggcgccacc ucccggggga agaacagcgu ccacgccuac     2220

aagaaggcgg gcaccuacaa cgugacgcug aaggugaccg acgacaaggg cgccaccgcc     2280

accgaguccu ucacgaucga gaucaagaac gaggacacca ccacccccau cacgaaggag     2340

auggagccca acgacgacau caaggaggcc aacgggccga ucgucgaggg cgugaccgug     2400

aagggggacc ucaacggcag cgacgacgcc gacaccuucu acuucgacgu caaggaggac     2460

ggggacguga ccaucgagcu gcccuacucc ggcagcucca acuucacgug gcugguguac     2520

aaggagggcg acgaccagaa ccacaucgcg agcgggaucg acaagaacaa cuccaagguc     2580

ggcaccuuca agagcaccaa ggggcgccac uacguguuca ucuacaagca cgacuccgcc     2640

agcaacaucu ccuacagccu caacaucaag ggccugggga acgagaagcu gaaggagaag     2700

gagaacaacg acuccagcga caaggccacc gugaucccca acuucaacac gaccaugcag     2760

ggcucccucc ugggcgacga cagccgggac uacuacuccu ucgaggucaa ggaggagggg     2820

gaggugaaca ucgagcugga caagaaggac gaguucggcg ugaccuggac ccuccacccc     2880

gagagcaaca ucaacgaccg caucacguac gggcaggucg acggcaacaa ggugagcaac     2940

aaggugaagc ugcggccggg caaguacuac cugcucgucu acaaguacuc cgggagcggc     3000

aacuacgagc ugcgcgugaa caaguga                                         3027


<210>  5205
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5205
augaagaaga acauccugaa gauccucaug gacagcuacu ccaaggagag caagauccag       60

accgugcgcc gggucaccuc cgugagccug cuggccgugu accucacgau gaacaccucc      120

agccuggucc uggccaagcc caucgagaac accaacgaca ccuccaucaa gaacguggag      180

aagcuccgca acgcgcccaa cgaggagaac agcaagaagg uggaggacuc caagaacgac      240

aaggucgagc acgugaagaa caucgaggag gccaaggugg agcaggucgc ccccgaggug      300

aagagcaagu ccacgcugcg gagcgccucc cgccggcgcc ggaagcgcau cgccaacacc      360

aacagcgaga aguacgacuu cgaguaccug aacggccucu ccuacaccga gcugaccaac      420

cugaucaaga acaucaagug gaaccagauc aacgggcucu ucaacuacag cacgggcucc      480

cagaaguucu ucggggacaa gaaccgcgug caggcgauca ucaacgcccu gcaggagagc      540

ggccggaccu acaccgccaa cgacaugaag gggaucgaga ccuucacgga gguccugcgc      600

gccggcuucu accucggcua cuacaacgac gggcuguccu accugaacga ccggaacuuc      660

caggacaagu gcauccccgc gaugaucgcc auccagaaga accccaacuu caagcucggc      720

accgccgugc aggacgaggu gaucaccagc cuggggaagc ugaucggcaa cgccagcgcc      780

aacgcggagg ucgugaacaa cugcgugccg guccucaagc aguuccgcga gaaccugaac      840

caguacgccc ccgacuacgu gaaggggacc gccgugaacg agcugaucaa gggcaucgag      900

uucgacuucu ccggcgccgc cuacgagaag gacgucaaga cgaugcccug guacgggaag      960

aucgaccccu ucaucaacga gcucaaggcg cugggccugu acgggaacau caccagcgcc     1020

accgaguggg ccuccgacgu gggcaucuac uaccucagca aguucggccu guacuccacc     1080

aaccggaacg acaucgugca gagccuggag aaggccgucg acauguacaa guacgggaag     1140

aucgccuucg uggcgaugga gcgcaucacg ugggacuacg acggcaucgg guccaacggc     1200

aagaaggucg accacgacaa guuccucgac gacgccgaga agcacuaccu gccgaagacc     1260

uacaccuucg acaacgggac cuucaucauc cgggccggcg acaaggugag cgaggagaag     1320

aucaagcgcc uguacugggc cucccgggag gugaagagcc aguuccaccg cgucgugggc     1380

aacgacaagg cccucgaggu ggggaacgcg gacgacgucc ugacgaugaa gaucuucaac     1440

ucccccgagg aguacaaguu caacaccaac aucaacggcg ugagcaccga caacgggggc     1500

cuguacaucg agccgcgggg gaccuucuac acguacgagc gcaccccgca gcaguccauc     1560

uucagccucg aggagcuguu ccggcacgag uacacccacu accugcaggc ccgcuaccuc     1620

guggacggcc uguggggcca ggggccguuc uacgagaaga accggcugac cugguucgac     1680

gagggcacgg ccgaguucuu cgccgggucc acccgcacca gcggcguccu cccccggaag     1740

uccauccugg gguaccuggc gaaggacaag guggaccacc gcuacagccu caagaagacc     1800

cugaacuccg gcuacgacga cagcgacugg auguucuaca acuacggcuu cgccguggcc     1860

cacuaccugu acgagaagga caugcccacg uucaucaaga ugaacaaggc cauccugaac     1920

accgacguca agagcuacga cgagaucauc aagaagcucu ccgacgacgc caacaagaac     1980

accgaguacc agaaccacau ccaggagcug gcggacaagu accagggggc cggcaucccc     2040

cuggugagcg acgacuaccu caaggaccac ggguacaaga aggccuccga gguguacagc     2100

gagaucucca aggccgccag ccugaccaac accuccguca cggcggagaa gagccaguac     2160

uucaacaccu ucacccugcg cggcaccuac acgggcgaga ccuccaaggg ggaguucaag     2220

gacugggacg agaugagcaa gaagcucgac ggcacccugg agucccuggc caagaacagc     2280

ugguccgggu acaagacccu cacggccuac uucaccaacu accgggugac cagcgacaac     2340

aaggugcagu acgacgucgu guuccacggc gugcugaccg acaacgccga caucuccaac     2400

aacaaggccc cgaucgcgaa ggucacgggg cccagcaccg gcgccguggg ccgcaacauc     2460

gaguucuccg ggaaggacag caaggacgag gacggcaaga ucgugagcua cgacugggac     2520

uucggggacg gcgccaccuc ccgggggaag aacagcgucc acgccuacaa gaaggcgggc     2580

accuacaacg ugacgcugaa ggugaccgac gacaagggcg ccaccgccac cgaguccuuc     2640

acgaucgaga ucaagaacga ggacaccacc acccccauca cgaaggagau ggagcccaac     2700

gacgacauca aggaggccaa cgggccgauc gucgagggcg ugaccgugaa gggggaccuc     2760

aacggcagcg acgacgccga caccuucuac uucgacguca aggaggacgg ggacgugacc     2820

aucgagcugc ccuacuccgg cagcuccaac uucacguggc ugguguacaa ggagggcgac     2880

gaccagaacc acaucgcgag cgggaucgac aagaacaacu ccaaggucgg caccuucaag     2940

agcaccaagg ggcgccacua cguguucauc uacaagcacg acuccgccag caacaucucc     3000

uacagccuca acaucaaggg ccuggggaac gagaagcuga aggagaagga gaacaacgac     3060

uccagcgaca aggccaccgu gauccccaac uucaacacga ccaugcaggg cucccuccug     3120

ggcgacgaca gccgggacua cuacuccuuc gaggucaagg aggaggggga ggugaacauc     3180

gagcuggaca agaaggacga guucggcgug accuggaccc uccaccccga gagcaacauc     3240

aacgaccgca ucacguacgg gcaggucgac ggcaacaagg ugagcaacaa ggugaagcug     3300

cggccgggca aguacuaccu gcucgucuac aaguacuccg ggagcggcaa cuacgagcug     3360

cgcgugaaca aguga                                                      3375


<210>  5206
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5206
gugcagaacg agagcaagcg cuacaccgug uccuaccuca agacgcugaa cuacuacgac       60

cuggucgacc uccuggugaa gaccgagauc gagaaccugc ccgaccucuu ccaguacagc      120

uccgacgcga aggaguucua cggcaacaag acccggauga gcuucaucau ggacgagauc      180

gggcgccggg ccccgcagua caccgagauc gaccacaagg gcauccccac gcugguggag      240

gucgugcgcg ccggguucua ccugggcuuc cacaacaagg agcucaacga gaucaacaag      300

cgguccuuca aggagcgcgu gauccccagc auccuggcca uccagaagaa cccgaacuuc      360

aagcugggga ccgaggucca ggacaagauc guguccgcga ccggccuccu ggccggcaac      420

gagaccgccc cgcccgaggu ggucaacaac uucacgccca uccugcagga cugcaucaag      480

aacaucgacc gguacgcccu cgacgaccug aagagcaagg cccuguucaa cgugcucgcg      540

gccccgaccu acgacaucac cgaguaccug cgcgccacca aggagaagcc cgagaacacg      600

ccgugguacg ggaagaucga cggcuucauc aacgagcuga agaagcucgc ccuguacggg      660

aagaucaacg acaacaacuc cuggaucauc gacaacggca ucuaccacau cgccccccug      720

gggaagcucc acagcaacaa caagaucggc aucgagaccc ugaccgaggu gaugaagguc      780

uacccguacc uguccaugca gcaccuccag agcgcggacc agaucaagcg gcacuacgac      840

uccaaggacg ccgagggcaa caagaucccc cuggacaagu ucaagaagga ggggaaggag      900

aaguacugcc ccaagaccua cacguucgac gacggcaagg ugaucaucaa ggccggggcc      960

cgcguggagg aggagaaggu caagcggcug uacugggcca gcaaggaggu gaacucccag     1020

uucuuccgcg uguacggcau cgacaagccc cucgaggagg gcaacccgga cgacauccug     1080

accaugguca ucuacaacag ccccgaggag uacaagcuga acuccgugcu cuacggguac     1140

gacaccaaca acggcgggau guacaucgag cccgagggca ccuucuucac guacgagcgg     1200

gaggcgcagg agagcaccua cacccuggag gagcuguucc gccacgagua cacccacuac     1260

cuccaggggc gguacgccgu gcccggccag uggggccgca cgaagcugua cgacaacgac     1320

cggcugaccu gguacgagga gggcggcgcc gagcucuucg ccgggagcac ccgcaccucc     1380

gggauccugc cgcggaagag caucgucucc aacauccaca acacgacccg caacaaccgc     1440

uacaagcuga gcgacaccgu gcacuccaag uacggggcca gcuucgaguu cuacaacuac     1500

gcgugcaugu ucauggacua cauguacaac aaggacaugg gcauccucaa caagcugaac     1560

gaccuggcca agaacaacga cgucgacggc uacgacaacu acauccggga ccuguccagc     1620

aacuacgccc ucaacgacaa guaccaggac cacaugcagg agcgcaucga caacuacgag     1680

aaccugaccg ugcccuucgu ggccgacgac uaccuggucc ggcacgcgua caagaacccc     1740

aacgagaucu acuccgagau cagcgaggug gccaagcuca aggacgccaa guccgaggug     1800

aagaagagcc aguacuucuc cacguucacc cugcgcggga gcuacaccgg cggggccucc     1860

aagggcaagc uggaggacca gaaggccaug aacaaguuca ucgacgacag ccucaagaag     1920

cuggacaccu acuccuggag cggguacaag acccugacgg cguacuucac caacuacaag     1980

gucgacucca gcaaccgggu gaccuacgac guggucuucc acggcuaccu ccccaacgag     2040

ggcgacagca agaacucccu gccguacggg aagaucaacg gcaccuacaa ggggacggag     2100

aaggagaaga ucaaguucag cuccgagggc agcuucgacc ccgacggcaa gaucgugucc     2160

uacgaguggg acuucgggga cggcaacaag agcaacgagg agaaccccga gcacuccuac     2220

gacaaggugg ggaccuacac cgucaagcug aaggugaccg acgacaaggg cgagagcucc     2280

gugagcacga ccaccgccga gaucaaggac cucuccgaga acaagcugcc cgucaucuac     2340

augcacgugc cgaagagcgg ggcccugaac cagaaggugg ucuucuacgg caagggcacc     2400

uacgaccccg acggguccau cgccggcuac cagugggacu ucggggacgg cagcgacuuc     2460

uccagcgagc agaaccccuc ccacguguac acgaagaagg gggaguacac cgugacccuc     2520

cgcgucaugg acagcagcgg ccagaugucc gagaagacca ugaagaucaa gaucacggac     2580

ccgguguacc ccaucggcac cgagaaggag cccaacaaca gcaaggagac cgccuccggg     2640

cccaucgugc cgggcauccc cgucagcggg accaucgaga acacguccga ccaggacuac     2700

uucuacuucg acgugaucac ccccggcgag gugaagaucg acaucaacaa gcugggguac     2760

ggcggcgcga ccugggucgu guacgacgag aacaacaacg ccgugagcua cgccaccgac     2820

gacgggcaga accuguccgg caaguucaag gccgacaagc ccgggcggua cuacauccac     2880

cucuacaugu ucaacggcag cuacaugccg uaccgcauca acaucgaggg guccgucggc     2940

cgguga                                                                2946


<210>  5207
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt1) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5207
augaagcgca agugccugag caagcggcuc augcuggcca ucaccauggc caccaucuuc       60

acggugaacu ccacccugcc caucuacgcg gccgucgaca agaacaacgc caccgccgcc      120

cgccggcgcc ggaagcgcgu gcagaacgag agcaagcgcu acaccguguc cuaccucaag      180

acgcugaacu acuacgaccu ggucgaccuc cuggugaaga ccgagaucga gaaccugccc      240

gaccucuucc aguacagcuc cgacgcgaag gaguucuacg gcaacaagac ccggaugagc      300

uucaucaugg acgagaucgg gcgccgggcc ccgcaguaca ccgagaucga ccacaagggc      360

auccccacgc ugguggaggu cgugcgcgcc ggguucuacc ugggcuucca caacaaggag      420

cucaacgaga ucaacaagcg guccuucaag gagcgcguga uccccagcau ccuggccauc      480

cagaagaacc cgaacuucaa gcuggggacc gagguccagg acaagaucgu guccgcgacc      540

ggccuccugg ccggcaacga gaccgccccg cccgaggugg ucaacaacuu cacgcccauc      600

cugcaggacu gcaucaagaa caucgaccgg uacgcccucg acgaccugaa gagcaaggcc      660

cuguucaacg ugcucgcggc cccgaccuac gacaucaccg aguaccugcg cgccaccaag      720

gagaagcccg agaacacgcc gugguacggg aagaucgacg gcuucaucaa cgagcugaag      780

aagcucgccc uguacgggaa gaucaacgac aacaacuccu ggaucaucga caacggcauc      840

uaccacaucg ccccccuggg gaagcuccac agcaacaaca agaucggcau cgagacccug      900

accgagguga ugaaggucua cccguaccug uccaugcagc accuccagag cgcggaccag      960

aucaagcggc acuacgacuc caaggacgcc gagggcaaca agaucccccu ggacaaguuc     1020

aagaaggagg ggaaggagaa guacugcccc aagaccuaca cguucgacga cggcaaggug     1080

aucaucaagg ccggggcccg cguggaggag gagaagguca agcggcugua cugggccagc     1140

aaggagguga acucccaguu cuuccgcgug uacggcaucg acaagccccu cgaggagggc     1200

aacccggacg acauccugac cauggucauc uacaacagcc ccgaggagua caagcugaac     1260

uccgugcucu acggguacga caccaacaac ggcgggaugu acaucgagcc cgagggcacc     1320

uucuucacgu acgagcggga ggcgcaggag agcaccuaca cccuggagga gcuguuccgc     1380

cacgaguaca cccacuaccu ccaggggcgg uacgccgugc ccggccagug gggccgcacg     1440

aagcuguacg acaacgaccg gcugaccugg uacgaggagg gcggcgccga gcucuucgcc     1500

gggagcaccc gcaccuccgg gauccugccg cggaagagca ucgucuccaa cauccacaac     1560

acgacccgca acaaccgcua caagcugagc gacaccgugc acuccaagua cggggccagc     1620

uucgaguucu acaacuacgc gugcauguuc auggacuaca uguacaacaa ggacaugggc     1680

auccucaaca agcugaacga ccuggccaag aacaacgacg ucgacggcua cgacaacuac     1740

auccgggacc uguccagcaa cuacgcccuc aacgacaagu accaggacca caugcaggag     1800

cgcaucgaca acuacgagaa ccugaccgug cccuucgugg ccgacgacua ccugguccgg     1860

cacgcguaca agaaccccaa cgagaucuac uccgagauca gcgagguggc caagcucaag     1920

gacgccaagu ccgaggugaa gaagagccag uacuucucca cguucacccu gcgcgggagc     1980

uacaccggcg gggccuccaa gggcaagcug gaggaccaga aggccaugaa caaguucauc     2040

gacgacagcc ucaagaagcu ggacaccuac uccuggagcg gguacaagac ccugacggcg     2100

uacuucacca acuacaaggu cgacuccagc aaccggguga ccuacgacgu ggucuuccac     2160

ggcuaccucc ccaacgaggg cgacagcaag aacucccugc cguacgggaa gaucaacggc     2220

accuacaagg ggacggagaa ggagaagauc aaguucagcu ccgagggcag cuucgacccc     2280

gacggcaaga ucguguccua cgagugggac uucggggacg gcaacaagag caacgaggag     2340

aaccccgagc acuccuacga caaggugggg accuacaccg ucaagcugaa ggugaccgac     2400

gacaagggcg agagcuccgu gagcacgacc accgccgaga ucaaggaccu cuccgagaac     2460

aagcugcccg ucaucuacau gcacgugccg aagagcgggg cccugaacca gaaggugguc     2520

uucuacggca agggcaccua cgaccccgac ggguccaucg ccggcuacca gugggacuuc     2580

ggggacggca gcgacuucuc cagcgagcag aaccccuccc acguguacac gaagaagggg     2640

gaguacaccg ugacccuccg cgucauggac agcagcggcc agauguccga gaagaccaug     2700

aagaucaaga ucacggaccc gguguacccc aucggcaccg agaaggagcc caacaacagc     2760

aaggagaccg ccuccgggcc caucgugccg ggcauccccg ucagcgggac caucgagaac     2820

acguccgacc aggacuacuu cuacuucgac gugaucaccc ccggcgaggu gaagaucgac     2880

aucaacaagc ugggguacgg cggcgcgacc ugggucgugu acgacgagaa caacaacgcc     2940

gugagcuacg ccaccgacga cgggcagaac cuguccggca aguucaaggc cgacaagccc     3000

gggcgguacu acauccaccu cuacauguuc aacggcagcu acaugccgua ccgcaucaac     3060

aucgaggggu ccgucggccg guga                                            3084


<210>  5208
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5208
aucgccaaca ccaacuccga gaaguacgac uucgaguacc ucaacggccu cuccuacacc       60

gagcucacca accucaucaa gaacaucaag uggaaccaga ucaacggccu cuucaacuac      120

uccaccggcu cccagaaguu cuucggcgac aagaaccgcg uccaggccau caucaacgcc      180

cuccaggagu ccggccgcac cuacaccgcc aacgacauga agggcaucga gaccuucacc      240

gagguccucc gcgccggcuu cuaccucggc uacuacaacg acggccucuc cuaccucaac      300

gaccgcaacu uccaggacaa gugcaucccc gccaugaucg ccauccagaa gaaccccaac      360

uucaagcucg gcaccgccgu ccaggacgag gucaucaccu cccucggcaa gcucaucggc      420

aacgccuccg ccaacgccga ggucgucaac aacugcgucc ccguccucaa gcaguuccgc      480

gagaaccuca accaguacgc ccccgacuac gucaagggca ccgccgucaa cgagcucauc      540

aagggcaucg aguucgacuu cuccggcgcc gccuacgaga aggacgucaa gaccaugccc      600

ugguacggca agaucgaccc cuucaucaac gagcucaagg cccucggccu cuacggcaac      660

aucaccuccg ccaccgagug ggccuccgac gucggcaucu acuaccucuc caaguucggc      720

cucuacucca ccaaccgcaa cgacaucguc cagucccucg agaaggccgu cgacauguac      780

aaguacggca agaucgccuu cgucgccaug gagcgcauca ccugggacua cgacggcauc      840

ggcuccaacg gcaagaaggu cgaccacgac aaguuccucg acgacgccga gaagcacuac      900

cuccccaaga ccuacaccuu cgacaacggc accuucauca uccgcgccgg cgacaagguc      960

uccgaggaga agaucaagcg ccucuacugg gccucccgcg aggucaaguc ccaguuccac     1020

cgcgucgucg gcaacgacaa ggcccucgag gucggcaacg ccgacgacgu ccucaccaug     1080

aagaucuuca acucccccga ggaguacaag uucaacacca acaucaacgg cgucuccacc     1140

gacaacggcg gccucuacau cgagccccgc ggcaccuucu acaccuacga gcgcaccccc     1200

cagcagucca ucuucucccu cgaggagcuc uuccgccacg aguacaccca cuaccuccag     1260

gcccgcuacc ucgucgacgg ccucuggggc cagggccccu ucuacgagaa gaaccgccuc     1320

accugguucg acgagggcac cgccgaguuc uucgccggcu ccacccgcac cuccggcguc     1380

cucccccgca aguccauccu cggcuaccuc gccaaggaca aggucgacca ccgcuacucc     1440

cucaagaaga cccucaacuc cggcuacgac gacuccgacu ggauguucua caacuacggc     1500

uucgccgucg cccacuaccu cuacgagaag gacaugccca ccuucaucaa gaugaacaag     1560

gccauccuca acaccgacgu caaguccuac gacgagauca ucaagaagcu cuccgacgac     1620

gccaacaaga acaccgagua ccagaaccac auccaggagc ucgccgacaa guaccagggc     1680

gccggcaucc cccucgucuc cgacgacuac cucaaggacc acggcuacaa gaaggccucc     1740

gaggucuacu ccgagaucuc caaggccgcc ucccucacca acaccuccgu caccgccgag     1800

aagucccagu acuucaacac cuucacccuc cgcggcaccu acaccggcga gaccuccaag     1860

ggcgaguuca aggacuggga cgagaugucc aagaagcucg acggcacccu cgagucccuc     1920

gccaagaacu ccugguccgg cuacaagacc cucaccgccu acuucaccaa cuaccgcguc     1980

accuccgaca acaaggucca guacgacguc gucuuccacg gcguccucac cgacaacgcc     2040

gacaucucca acaacaaggc ccccaucgcc aaggucaccg gccccuccac cggcgccguc     2100

ggccgcaaca ucgaguucuc cggcaaggac uccaaggacg aggacggcaa gaucgucucc     2160

uacgacuggg acuucggcga cggcgccacc ucccgcggca agaacuccgu ccacgccuac     2220

aagaaggccg gcaccuacaa cgucacccuc aaggucaccg acgacaaggg cgccaccgcc     2280

accgaguccu ucaccaucga gaucaagaac gaggacacca ccacccccau caccaaggag     2340

auggagccca acgacgacau caaggaggcc aacggcccca ucgucgaggg cgucaccguc     2400

aagggcgacc ucaacggcuc cgacgacgcc gacaccuucu acuucgacgu caaggaggac     2460

ggcgacguca ccaucgagcu ccccuacucc ggcuccucca acuucaccug gcucgucuac     2520

aaggagggcg acgaccagaa ccacaucgcc uccggcaucg acaagaacaa cuccaagguc     2580

ggcaccuuca aguccaccaa gggccgccac uacgucuuca ucuacaagca cgacuccgcc     2640

uccaacaucu ccuacucccu caacaucaag ggccucggca acgagaagcu caaggagaag     2700

gagaacaacg acuccuccga caaggccacc gucaucccca acuucaacac caccaugcag     2760

ggcucccucc ucggcgacga cucccgcgac uacuacuccu ucgaggucaa ggaggagggc     2820

gaggucaaca ucgagcucga caagaaggac gaguucggcg ucaccuggac ccuccacccc     2880

gaguccaaca ucaacgaccg caucaccuac ggccaggucg acggcaacaa ggucuccaac     2940

aaggucaagc uccgccccgg caaguacuac cuccucgucu acaaguacuc cggcuccggc     3000

aacuacgagc uccgcgucaa caaguga                                         3027


<210>  5209
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5209
augaagaaga acauccucaa gauccucaug gacuccuacu ccaaggaguc caagauccag       60

accguccgcc gcgucaccuc cgucucccuc cucgccgucu accucaccau gaacaccucc      120

ucccucgucc ucgccaagcc caucgagaac accaacgaca ccuccaucaa gaacgucgag      180

aagcuccgca acgcccccaa cgaggagaac uccaagaagg ucgaggacuc caagaacgac      240

aaggucgagc acgucaagaa caucgaggag gccaaggucg agcaggucgc ccccgagguc      300

aaguccaagu ccacccuccg cuccgccucc cgccgccgcc gcaagcgcau cgccaacacc      360

aacuccgaga aguacgacuu cgaguaccuc aacggccucu ccuacaccga gcucaccaac      420

cucaucaaga acaucaagug gaaccagauc aacggccucu ucaacuacuc caccggcucc      480

cagaaguucu ucggcgacaa gaaccgcguc caggccauca ucaacgcccu ccaggagucc      540

ggccgcaccu acaccgccaa cgacaugaag ggcaucgaga ccuucaccga gguccuccgc      600

gccggcuucu accucggcua cuacaacgac ggccucuccu accucaacga ccgcaacuuc      660

caggacaagu gcauccccgc caugaucgcc auccagaaga accccaacuu caagcucggc      720

accgccgucc aggacgaggu caucaccucc cucggcaagc ucaucggcaa cgccuccgcc      780

aacgccgagg ucgucaacaa cugcgucccc guccucaagc aguuccgcga gaaccucaac      840

caguacgccc ccgacuacgu caagggcacc gccgucaacg agcucaucaa gggcaucgag      900

uucgacuucu ccggcgccgc cuacgagaag gacgucaaga ccaugcccug guacggcaag      960

aucgaccccu ucaucaacga gcucaaggcc cucggccucu acggcaacau caccuccgcc     1020

accgaguggg ccuccgacgu cggcaucuac uaccucucca aguucggccu cuacuccacc     1080

aaccgcaacg acaucgucca gucccucgag aaggccgucg acauguacaa guacggcaag     1140

aucgccuucg ucgccaugga gcgcaucacc ugggacuacg acggcaucgg cuccaacggc     1200

aagaaggucg accacgacaa guuccucgac gacgccgaga agcacuaccu ccccaagacc     1260

uacaccuucg acaacggcac cuucaucauc cgcgccggcg acaaggucuc cgaggagaag     1320

aucaagcgcc ucuacugggc cucccgcgag gucaaguccc aguuccaccg cgucgucggc     1380

aacgacaagg cccucgaggu cggcaacgcc gacgacgucc ucaccaugaa gaucuucaac     1440

ucccccgagg aguacaaguu caacaccaac aucaacggcg ucuccaccga caacggcggc     1500

cucuacaucg agccccgcgg caccuucuac accuacgagc gcacccccca gcaguccauc     1560

uucucccucg aggagcucuu ccgccacgag uacacccacu accuccaggc ccgcuaccuc     1620

gucgacggcc ucuggggcca gggccccuuc uacgagaaga accgccucac cugguucgac     1680

gagggcaccg ccgaguucuu cgccggcucc acccgcaccu ccggcguccu cccccgcaag     1740

uccauccucg gcuaccucgc caaggacaag gucgaccacc gcuacucccu caagaagacc     1800

cucaacuccg gcuacgacga cuccgacugg auguucuaca acuacggcuu cgccgucgcc     1860

cacuaccucu acgagaagga caugcccacc uucaucaaga ugaacaaggc cauccucaac     1920

accgacguca aguccuacga cgagaucauc aagaagcucu ccgacgacgc caacaagaac     1980

accgaguacc agaaccacau ccaggagcuc gccgacaagu accagggcgc cggcaucccc     2040

cucgucuccg acgacuaccu caaggaccac ggcuacaaga aggccuccga ggucuacucc     2100

gagaucucca aggccgccuc ccucaccaac accuccguca ccgccgagaa gucccaguac     2160

uucaacaccu ucacccuccg cggcaccuac accggcgaga ccuccaaggg cgaguucaag     2220

gacugggacg agauguccaa gaagcucgac ggcacccucg agucccucgc caagaacucc     2280

ugguccggcu acaagacccu caccgccuac uucaccaacu accgcgucac cuccgacaac     2340

aagguccagu acgacgucgu cuuccacggc guccucaccg acaacgccga caucuccaac     2400

aacaaggccc ccaucgccaa ggucaccggc cccuccaccg gcgccgucgg ccgcaacauc     2460

gaguucuccg gcaaggacuc caaggacgag gacggcaaga ucgucuccua cgacugggac     2520

uucggcgacg gcgccaccuc ccgcggcaag aacuccgucc acgccuacaa gaaggccggc     2580

accuacaacg ucacccucaa ggucaccgac gacaagggcg ccaccgccac cgaguccuuc     2640

accaucgaga ucaagaacga ggacaccacc acccccauca ccaaggagau ggagcccaac     2700

gacgacauca aggaggccaa cggccccauc gucgagggcg ucaccgucaa gggcgaccuc     2760

aacggcuccg acgacgccga caccuucuac uucgacguca aggaggacgg cgacgucacc     2820

aucgagcucc ccuacuccgg cuccuccaac uucaccuggc ucgucuacaa ggagggcgac     2880

gaccagaacc acaucgccuc cggcaucgac aagaacaacu ccaaggucgg caccuucaag     2940

uccaccaagg gccgccacua cgucuucauc uacaagcacg acuccgccuc caacaucucc     3000

uacucccuca acaucaaggg ccucggcaac gagaagcuca aggagaagga gaacaacgac     3060

uccuccgaca aggccaccgu cauccccaac uucaacacca ccaugcaggg cucccuccuc     3120

ggcgacgacu cccgcgacua cuacuccuuc gaggucaagg aggagggcga ggucaacauc     3180

gagcucgaca agaaggacga guucggcguc accuggaccc uccaccccga guccaacauc     3240

aacgaccgca ucaccuacgg ccaggucgac ggcaacaagg ucuccaacaa ggucaagcuc     3300

cgccccggca aguacuaccu ccucgucuac aaguacuccg gcuccggcaa cuacgagcuc     3360

cgcgucaaca aguga                                                      3375


<210>  5210
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5210
guccagaacg aguccaagcg cuacaccguc uccuaccuca agacccucaa cuacuacgac       60

cucgucgacc uccucgucaa gaccgagauc gagaaccucc ccgaccucuu ccaguacucc      120

uccgacgcca aggaguucua cggcaacaag acccgcaugu ccuucaucau ggacgagauc      180

ggccgccgcg ccccccagua caccgagauc gaccacaagg gcauccccac ccucgucgag      240

gucguccgcg ccggcuucua ccucggcuuc cacaacaagg agcucaacga gaucaacaag      300

cgcuccuuca aggagcgcgu cauccccucc auccucgcca uccagaagaa ccccaacuuc      360

aagcucggca ccgaggucca ggacaagauc gucuccgcca ccggccuccu cgccggcaac      420

gagaccgccc cccccgaggu cgucaacaac uucaccccca uccuccagga cugcaucaag      480

aacaucgacc gcuacgcccu cgacgaccuc aaguccaagg cccucuucaa cguccucgcc      540

gcccccaccu acgacaucac cgaguaccuc cgcgccacca aggagaagcc cgagaacacc      600

cccugguacg gcaagaucga cggcuucauc aacgagcuca agaagcucgc ccucuacggc      660

aagaucaacg acaacaacuc cuggaucauc gacaacggca ucuaccacau cgccccccuc      720

ggcaagcucc acuccaacaa caagaucggc aucgagaccc ucaccgaggu caugaagguc      780

uaccccuacc ucuccaugca gcaccuccag uccgccgacc agaucaagcg ccacuacgac      840

uccaaggacg ccgagggcaa caagaucccc cucgacaagu ucaagaagga gggcaaggag      900

aaguacugcc ccaagaccua caccuucgac gacggcaagg ucaucaucaa ggccggcgcc      960

cgcgucgagg aggagaaggu caagcgccuc uacugggccu ccaaggaggu caacucccag     1020

uucuuccgcg ucuacggcau cgacaagccc cucgaggagg gcaaccccga cgacauccuc     1080

accaugguca ucuacaacuc ccccgaggag uacaagcuca acuccguccu cuacggcuac     1140

gacaccaaca acggcggcau guacaucgag cccgagggca ccuucuucac cuacgagcgc     1200

gaggcccagg aguccaccua cacccucgag gagcucuucc gccacgagua cacccacuac     1260

cuccagggcc gcuacgccgu ccccggccag uggggccgca ccaagcucua cgacaacgac     1320

cgccucaccu gguacgagga gggcggcgcc gagcucuucg ccggcuccac ccgcaccucc     1380

ggcauccucc cccgcaaguc caucgucucc aacauccaca acaccacccg caacaaccgc     1440

uacaagcucu ccgacaccgu ccacuccaag uacggcgccu ccuucgaguu cuacaacuac     1500

gccugcaugu ucauggacua cauguacaac aaggacaugg gcauccucaa caagcucaac     1560

gaccucgcca agaacaacga cgucgacggc uacgacaacu acauccgcga ccucuccucc     1620

aacuacgccc ucaacgacaa guaccaggac cacaugcagg agcgcaucga caacuacgag     1680

aaccucaccg uccccuucgu cgccgacgac uaccucgucc gccacgccua caagaacccc     1740

aacgagaucu acuccgagau cuccgagguc gccaagcuca aggacgccaa guccgagguc     1800

aagaaguccc aguacuucuc caccuucacc cuccgcggcu ccuacaccgg cggcgccucc     1860

aagggcaagc ucgaggacca gaaggccaug aacaaguuca ucgacgacuc ccucaagaag     1920

cucgacaccu acuccugguc cggcuacaag acccucaccg ccuacuucac caacuacaag     1980

gucgacuccu ccaaccgcgu caccuacgac gucgucuucc acggcuaccu ccccaacgag     2040

ggcgacucca agaacucccu ccccuacggc aagaucaacg gcaccuacaa gggcaccgag     2100

aaggagaaga ucaaguucuc cuccgagggc uccuucgacc ccgacggcaa gaucgucucc     2160

uacgaguggg acuucggcga cggcaacaag uccaacgagg agaaccccga gcacuccuac     2220

gacaaggucg gcaccuacac cgucaagcuc aaggucaccg acgacaaggg cgaguccucc     2280

gucuccacca ccaccgccga gaucaaggac cucuccgaga acaagcuccc cgucaucuac     2340

augcacgucc ccaaguccgg cgcccucaac cagaaggucg ucuucuacgg caagggcacc     2400

uacgaccccg acggcuccau cgccggcuac cagugggacu ucggcgacgg cuccgacuuc     2460

uccuccgagc agaaccccuc ccacgucuac accaagaagg gcgaguacac cgucacccuc     2520

cgcgucaugg acuccuccgg ccagaugucc gagaagacca ugaagaucaa gaucaccgac     2580

cccgucuacc ccaucggcac cgagaaggag cccaacaacu ccaaggagac cgccuccggc     2640

cccaucgucc ccggcauccc cgucuccggc accaucgaga acaccuccga ccaggacuac     2700

uucuacuucg acgucaucac ccccggcgag gucaagaucg acaucaacaa gcucggcuac     2760

ggcggcgcca ccugggucgu cuacgacgag aacaacaacg ccgucuccua cgccaccgac     2820

gacggccaga accucuccgg caaguucaag gccgacaagc ccggccgcua cuacauccac     2880

cucuacaugu ucaacggcuc cuacaugccc uaccgcauca acaucgaggg cuccgucggc     2940

cgcuga                                                                2946


<210>  5211
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt2) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5211
augaagcgca agugccucuc caagcgccuc augcucgcca ucaccauggc caccaucuuc       60

accgucaacu ccacccuccc caucuacgcc gccgucgaca agaacaacgc caccgccgcc      120

cgccgccgcc gcaagcgcgu ccagaacgag uccaagcgcu acaccgucuc cuaccucaag      180

acccucaacu acuacgaccu cgucgaccuc cucgucaaga ccgagaucga gaaccucccc      240

gaccucuucc aguacuccuc cgacgccaag gaguucuacg gcaacaagac ccgcaugucc      300

uucaucaugg acgagaucgg ccgccgcgcc ccccaguaca ccgagaucga ccacaagggc      360

auccccaccc ucgucgaggu cguccgcgcc ggcuucuacc ucggcuucca caacaaggag      420

cucaacgaga ucaacaagcg cuccuucaag gagcgcguca uccccuccau ccucgccauc      480

cagaagaacc ccaacuucaa gcucggcacc gagguccagg acaagaucgu cuccgccacc      540

ggccuccucg ccggcaacga gaccgccccc cccgaggucg ucaacaacuu cacccccauc      600

cuccaggacu gcaucaagaa caucgaccgc uacgcccucg acgaccucaa guccaaggcc      660

cucuucaacg uccucgccgc ccccaccuac gacaucaccg aguaccuccg cgccaccaag      720

gagaagcccg agaacacccc cugguacggc aagaucgacg gcuucaucaa cgagcucaag      780

aagcucgccc ucuacggcaa gaucaacgac aacaacuccu ggaucaucga caacggcauc      840

uaccacaucg ccccccucgg caagcuccac uccaacaaca agaucggcau cgagacccuc      900

accgagguca ugaaggucua ccccuaccuc uccaugcagc accuccaguc cgccgaccag      960

aucaagcgcc acuacgacuc caaggacgcc gagggcaaca agaucccccu cgacaaguuc     1020

aagaaggagg gcaaggagaa guacugcccc aagaccuaca ccuucgacga cggcaagguc     1080

aucaucaagg ccggcgcccg cgucgaggag gagaagguca agcgccucua cugggccucc     1140

aaggagguca acucccaguu cuuccgcguc uacggcaucg acaagccccu cgaggagggc     1200

aaccccgacg acauccucac cauggucauc uacaacuccc ccgaggagua caagcucaac     1260

uccguccucu acggcuacga caccaacaac ggcggcaugu acaucgagcc cgagggcacc     1320

uucuucaccu acgagcgcga ggcccaggag uccaccuaca cccucgagga gcucuuccgc     1380

cacgaguaca cccacuaccu ccagggccgc uacgccgucc ccggccagug gggccgcacc     1440

aagcucuacg acaacgaccg ccucaccugg uacgaggagg gcggcgccga gcucuucgcc     1500

ggcuccaccc gcaccuccgg cauccucccc cgcaagucca ucgucuccaa cauccacaac     1560

accacccgca acaaccgcua caagcucucc gacaccgucc acuccaagua cggcgccucc     1620

uucgaguucu acaacuacgc cugcauguuc auggacuaca uguacaacaa ggacaugggc     1680

auccucaaca agcucaacga ccucgccaag aacaacgacg ucgacggcua cgacaacuac     1740

auccgcgacc ucuccuccaa cuacgcccuc aacgacaagu accaggacca caugcaggag     1800

cgcaucgaca acuacgagaa ccucaccguc cccuucgucg ccgacgacua ccucguccgc     1860

cacgccuaca agaaccccaa cgagaucuac uccgagaucu ccgaggucgc caagcucaag     1920

gacgccaagu ccgaggucaa gaagucccag uacuucucca ccuucacccu ccgcggcucc     1980

uacaccggcg gcgccuccaa gggcaagcuc gaggaccaga aggccaugaa caaguucauc     2040

gacgacuccc ucaagaagcu cgacaccuac uccugguccg gcuacaagac ccucaccgcc     2100

uacuucacca acuacaaggu cgacuccucc aaccgcguca ccuacgacgu cgucuuccac     2160

ggcuaccucc ccaacgaggg cgacuccaag aacucccucc ccuacggcaa gaucaacggc     2220

accuacaagg gcaccgagaa ggagaagauc aaguucuccu ccgagggcuc cuucgacccc     2280

gacggcaaga ucgucuccua cgagugggac uucggcgacg gcaacaaguc caacgaggag     2340

aaccccgagc acuccuacga caaggucggc accuacaccg ucaagcucaa ggucaccgac     2400

gacaagggcg aguccuccgu cuccaccacc accgccgaga ucaaggaccu cuccgagaac     2460

aagcuccccg ucaucuacau gcacgucccc aaguccggcg cccucaacca gaaggucguc     2520

uucuacggca agggcaccua cgaccccgac ggcuccaucg ccggcuacca gugggacuuc     2580

ggcgacggcu ccgacuucuc cuccgagcag aaccccuccc acgucuacac caagaagggc     2640

gaguacaccg ucacccuccg cgucauggac uccuccggcc agauguccga gaagaccaug     2700

aagaucaaga ucaccgaccc cgucuacccc aucggcaccg agaaggagcc caacaacucc     2760

aaggagaccg ccuccggccc caucgucccc ggcauccccg ucuccggcac caucgagaac     2820

accuccgacc aggacuacuu cuacuucgac gucaucaccc ccggcgaggu caagaucgac     2880

aucaacaagc ucggcuacgg cggcgccacc ugggucgucu acgacgagaa caacaacgcc     2940

gucuccuacg ccaccgacga cggccagaac cucuccggca aguucaaggc cgacaagccc     3000

ggccgcuacu acauccaccu cuacauguuc aacggcuccu acaugcccua ccgcaucaac     3060

aucgagggcu ccgucggccg cuga                                            3084


<210>  5212
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5212
auugcuaaca caaauaguga gaaauaugac uuugaauacc ugaacggcuu gagcuauacu       60

gaguuaacga aucugauaaa gaacaucaaa uggaaucaga uuaacgggcu auucaauuac      120

uccaccggau cucaaaaguu uuucggugau aaaaacagag uccaggcaau cauuaaugcc      180

cuccaggaau cgggcaggac auauacugcg aacgacauga aggggaucga gaccuuuaca      240

gaaguucugc gggcuggauu cuaccuuggc uauuacaaug auggucuguc auacuugaac      300

gaccgcaauu uucaggauaa gugcauaccc gccaugaucg caauucagaa aaacccuaau      360

uucaagcucg ggaccgccgu gcaagacgag guaaucacua gccugggaaa acugauuggc      420

aacgcuagug caaacgccga gguggucaau aacugugugc caguucucaa gcaguuucga      480

gaaaauuuaa accaguaugc uccggauuac gugaaaggca cagccgucaa ugagcugauc      540

aaggggauag aauuugacuu uuccggagcg gcauaugaga aggaugugaa aaccaugccc      600

ugguacggua agauugaccc uuucaucaac gagcuuaaag ccuugggccu guaugggaau      660

auuacgucug cuacugaaug ggccagcgau guaggaaucu acuaucuauc caaguucggc      720

cucuacucaa ccaaccguaa ugacaucguu caaagucugg agaaagcagu ggauauguac      780

aaguauggua aaauugcuuu ugucgccaug gaaagaauaa caugggacua cgacgggauc      840

ggaagcaacg gcaagaaggu ggaucacgac aaauuccuug augacgcgga gaagcauuau      900

cugccaaaaa cuuacaccuu ugauaauggc acauucauua ucagggccgg ggacaaggug      960

ucugaagaga aaauaaagcg guuguauugg gcaucccgcg aggucaaguc acaguuucac     1020

agaguugugg gaaacgauaa agcucucgaa guagguaaug ccgacgaugu gcugaccaug     1080

aagauuuuca acagccccga ggaauacaaa uuuaauacga acaucaacgg cgucaguacu     1140

gacaaugggg gauuauauau cgagccuagg ggcacauucu acaccuacga acggacucca     1200

cagcagucua uuuucucccu ggaggagcug uuccgccaug aauauacaca cuaccuucaa     1260

gcucgauauc ugguggaugg uuuguggggg cagggccccu uuuacgagaa gaacagacua     1320

accugguucg acgaaggaac ggccgaguuu uucgcaggca gcaccaggac aucggggguu     1380

cugccucgga aaucuauccu cggauaucug gccaaggaca agguggauca ucguuacucc     1440

cuuaaaaaga cucucaauuc agguuaugac gauagugacu ggauguucua caacuacggc     1500

uuugcugucg cgcacuauuu guacgaaaaa gauaugccaa ccuucauuaa gaugaauaaa     1560

gcaauacuca acacagacgu aaagagcuau gaugagauca uuaagaaacu guccgacgau     1620

gccaauaaga acacugagua ccagaaucac auccaagaau uagcugacaa auaucagggg     1680

gccggaaucc cgcugguguc ugaugacuac cuaaaggauc auggcuauaa aaaggcaagc     1740

gagguuuacu cagaaauuag uaaagccgcu ucccucacca acacaagcgu gaccgccgag     1800

aagucucagu acuuuaauac uuucacgcug cgcgguacau auaccgggga gacuucaaag     1860

ggcgaauuua aagacuggga cgagaugagu aagaaacuug auggaaccuu ggaaagccug     1920

gcaaagaacu ccuggucugg cuacaaaaca cucaccgcgu auuucacuaa uuacagaguc     1980

acaucggaca acaaggugca guaugauguc guguuucacg ggguucugac ggacaaugcu     2040

gauauaagca acaacaaggc ccccaucgca aaagugaccg gaccuuccac uggugccgua     2100

ggcaggaaua uugaguucuc agggaaggac aguaaagaug aagacggaaa gaucgucucu     2160

uacgauuggg acuuuggcga uggugcuaca agccggggga aaaacuccgu gcaugccuau     2220

aagaaggcag gcaccuacaa uguuacacuu aaagugacug acgauaaggg agcuaccgcc     2280

acggagucau ucaccauuga gaucaaaaac gaagacacaa cuaccccaau aacaaaggag     2340

auggaaccca augacgauau caaagaggcg aacggcccua uugucgaagg ggugacugua     2400

aagggagacc ugaauggcag cgaugacgcc gauaccuuuu acuucgacgu gaaggaggau     2460

ggugacguua cgaucgaguu gccauauucu ggguccagua acuuuacaug gcucgucuac     2520

aaagaaggag augaccaaaa ucacauugcu agcggcaucg auaagaacaa uucuaaagug     2580

gguaccuuca aguccacuaa aggccgacac uauguguuca uauacaagca ugacucagca     2640

aguaacauua gcuauucgcu gaauaucaaa ggguuaggaa acgagaagcu gaaggaaaaa     2700

gagaauaacg acuccucuga uaaggccaca gucauuccca acuuuaauac cacuaugcag     2760

ggcagccuac ucggggacga uucacgcgac uacuauaguu ucgaaguuaa agaggaggga     2820

gaagugaaca ucgagcugga uaagaaagac gaauuuggcg ugaccuggac acuucacccg     2880

gaguccaaua uaaacgauag aaucacguac ggucagguag acgggaauaa ggucucuaac     2940

aaggugaaau ugaggccugg aaaguacuau cugcucguuu acaaauauag cggcuccggu     3000

aauuacgagc ugcgggugaa caaguga                                         3027


<210>  5213
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5213
augaaaaaga acauucugaa aauauugaug gacaguuaua gcaaggaguc caaaauccag       60

acagucagaa ggguuacuuc ugugucguua cuggcuguau accuaacgau gaauaccuca      120

agccucgugc uggcaaagcc cauugaaaac acaaaugaua cuagcaucaa gaacgucgag      180

aaacuucgga augccccuaa cgaagaaaau uccaagaaag uggaagacuc uaagaacgau      240

aaaguugagc acgugaagaa uauugaggaa gcgaaggucg agcaaguggc uccagaagua      300

aaaagcaagu ccacccugcg cucagccagu cgacguagaa ggaaacggau cgcaaacaca      360

aauagcgaga aguaugacuu ugaguacuug aacggccucu cuuauaccga acugacuaau      420

cugaucaaaa acauaaagug gaaucagauu aacggacucu ucaacuacuc cacaggauca      480

cagaaauuuu ucggugauaa gaaucgcguu caggccauca uuaacgcuuu acaagagagc      540

ggcagaaccu auacggcaaa ugacaugaag gggaucgaaa cuuuuaccga ggugcugagg      600

gccggauucu accuuggcua cuauaacgau gguuugaguu accugaauga ccggaacuuu      660

caggauaaau gcauaccggc uaugauugcc auccagaaga aucccaacuu caaacuaggg      720

acagcggucc aggacgaagu gauuacuucu cucggaaagc ugaucggcaa ugcauccgcc      780

aacgcugagg uggucaauaa cuguguuccu gugcuuaaac aauuucgcga gaaucugaac      840

caguaugccc cagauuacgu aaagggcacc gcagugaaug aauugaucaa ggggauugag      900

uucgacuuua gcggagcugc cuaugaaaaa gaugucaaga caaugcccug guacgguaaa      960

auagacccuu ucaucaacga gcucaaggcg cugggcuuau augggaacau uaccucggcc     1020

acggaauggg caucugacgu gggaaucuac uaccugucca aauucggccu cuauucaacu     1080

aaucgaaacg auauaguuca gagucuugag aaggcugugg acauguacaa guaugguaaa     1140

auugccuuug ucgcuaugga gagaaucaca ugggauuacg acgggaucgg aagcaauggc     1200

aagaaagugg aucaugacaa guuccuggau gacgccgaaa aacacuauuu gccaaagacc     1260

uacacuuuug auaacggcac auucauuauc agggcagggg acaagguauc cgaggagaaa     1320

auuaagcggc uauauugggc cucucgugag guuaaaagcc aguuucaucg cguggucgga     1380

aaugauaagg cucuggaagu ggguaacgcg gacgacgucc ucaccaugaa aauauucaau     1440

ucacccgagg aguacaaguu uaacacgaau aucaacggcg ugaguaccga uaauggggga     1500

cuguacauug aaccuagagg cacauucuau acuuacgaga ggaccccaca acaguccauc     1560

uuuagccuug aggaacuguu ccggcacgag uauacacauu acuugcaggc acgauaucuc     1620

guugacgguc ugugggggca aggcccguuu uacgagaaaa accgcuuaac uugguucgau     1680

gaaggaaccg ccgaauuuuu cgcuggcucu acaagaaccu caggggugcu gcccaggaag     1740

aguauccuag gauaucucgc caaggacaaa guagaucacc gguacagccu gaagaaaacu     1800

cuuaauuccg guuacgacga uucugacugg auguucuaua acuacggcuu ugcagucgcc     1860

cacuauuugu acgagaagga uaugccuacg uucauuaaaa ugaauaaggc uauacugaac     1920

acagacguga agucguauga ugaaaucauu aaaaagcuca gcgacgaugc caacaaaaau     1980

accgaguacc agaaccauau ccaggagcug gcagacaagu aucagggggc ggggauucca     2040

cuuguuuccg acgauuaccu gaaagaccac ggcuacaaga aggcuucaga aguguauagu     2100

gagaucucua aagccgcaag uuugacuaau accuccguca cagccgaaaa gucacaauac     2160

uuuaacaccu ucacucuccg cgguacauau acgggggaga ccagcaaagg cgaauuuaag     2220

gauugggacg agaugucuaa aaagcuggau ggaacuuuag agucccuggc uaagaauagu     2280

uggagcggcu acaaaacacu aaccgccuau uucacaaacu acagagugac uucugacaau     2340

aagguacagu augauguggu uuuucauggg guccucaccg acaacgcaga uauauccaau     2400

aacaaagcuc ccaucgccaa ggugacggga ccuucaaccg gugcgguggg caggaauauu     2460

gaguucagug ggaaagacag caaggaugaa gacggaaaaa ucgucucgua cgauugggac     2520

uuuggcgacg gugccacauc ccgugggaag aacucuguuc acgcuuacaa gaaagcaggc     2580

acuuauaaug ugacccugaa ggugacagau gacaaaggag ccacugcuac cgagagcuuc     2640

acgauugaaa ucaagaacga agauacaacc acuccaauaa caaaagagau ggagcccaau     2700

gacgauauua aggaagccaa cggcccgauc guagaggggg ucaccgugaa gggagaccuu     2760

aacggcucag augacgcaga uacuuuuuac uucgacguua aagaagaugg ugacgugacc     2820

auugaguugc cuuauagugg guccucuaau uuuacauggc uggucuacaa ggagggagac     2880

gaucagaacc acaucgcgag cggcauagac aaaaauaacu ccaagguggg uacguucaaa     2940

ucaaccaagg gccggcauua uguuuucauc uacaagcacg auagcgccag uaauauuucu     3000

uauucccuca acaucaaagg gcugggaaau gaaaaguuaa aagagaagga aaacaaugac     3060

agcucggaua aagcuacugu gauucccaac uuuaauacaa ccaugcaggg cucacugcuu     3120

ggggacgauu cucgagacua cuacaguuuc gagguaaagg aagagggaga ggucaacauc     3180

gaauuggaua agaaagacga guuuggcgug acauggacuc uccauccaga auccaauaua     3240

aacgauagaa uuaccuaugg ucaaguggac gggaauaagg ucagcaacaa aguuaagcug     3300

aggccuggaa aauacuaucu acugguguac aaguauucug gcagcgguaa uuacgagcuc     3360

cgcguaaaca aguga                                                      3375


<210>  5214
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5214
guccagaacg agaguaaaag auauacaguu agcuaccuga agacuuugaa uuauuacgac       60

uuaguggauc ugcuaguaaa aacggaaauu gagaaccucc ccgaccuguu ucaauauucc      120

ucugaugcua aggaguucua cggcaauaaa accaggaugu cguuuauaau ggacgaaauc      180

ggccggcgcg caccucagua uacagaaauu gaucacaagg gaaucccaac ucuuguggag      240

gucgugcgag ccgguuucua ccugggcuuu cauaacaagg aguugaauga aauuaacaaa      300

cguucauuca aggagagagu uaucccgagc auacucgcga uccagaaaaa ucccaacuuu      360

aagcugggga ccgaagugca ggacaaaauu gucagugcua caggacugcu cgccggcaau      420

gagaccgcac cuccagaggu gguaaacaau uucacuccca ucuuacaaga uugcauuaag      480

aacaucgaca gguacgcccu ggaugaccuu aaguccaagg cuuuguuuaa uguucuggca      540

gccccuacau augauauaac cgaauaccua cgggcuacga aggagaaacc agaaaacacu      600

cccugguaug guaagauuga cggguucauc aaugagcuca aaaagcuggc ccuuuacgga      660

aaaauuaacg auaacaauuc uuggaucauc gacaacggca uuuaucacau agcgccucug      720

ggcaaguugc auagcaauaa caagaucggg auugaaaccc ucacagaggu gaugaaaguc      780

uacccauauc uguccaugca gcacuuacag ucagcagacc agaucaagcg ccauuacgau      840

aguaaagacg ccgagggaaa uaagauaccg cuggauaaau uuaagaagga agguaaagag      900

aaguacuguc ccaaaacuua uaccuucgac gauggcaagg ugauuaucaa agcuggggcc      960

agaguggaag aggaaaaggu caagaggcuc uacugggcaa gcaaagaggu uaacucucaa     1020

uucuuucggg uguauggaau cgacaagccu cuugaggaag gcaauccaga ugacauucug     1080

acaaugguaa ucuacaacuc ccccgaggaa uauaaacuaa auucaguguu guacgguuau     1140

gauaccaaca augggggaau guacauugag ccugaaggca cguucuuuac uuacgagcgc     1200

gaggcucagg aaagcacaua uacccuggag gaacucuucc gacacgagua cacucacuau     1260

cugcagggca gauacgccgu cccagggcag uggggaagga caaaacuuua ugacaacgau     1320

cggcugaccu gguacgagga agguggcgcg gaguuguuug ccgggaguac gcguaccucu     1380

ggaauacucc cccgcaaauc caucgugagc aauauucaua acacaacuag aaauaacagg     1440

uauaagcugu cggacaccgu ucacucuaag uacggcgcau ccuucgaauu uuacaacuau     1500

gcuugcaugu ucauggacua cauguauaau aaagauaugg guaucuuaaa caagcugaau     1560

gaccuagcca aaaacaauga uguggacggg uacgauaacu auauccggga ccucucaagu     1620

aauuacgcuc ugaacgauaa guaucaagac cauaugcagg agcgaauuga uaauuacgaa     1680

aaccuuacag ucccguuugu ggccgacgau uacuugguac gccacgcaua uaaaaauccu     1740

aacgagauau acagcgagau cuccgaaguu gccaagcuga aagacgcuaa gucugaggug     1800

aagaaaagcc aguauuucuc aacuuuuacc cucagaggca guuacacagg aggcgcgucc     1860

aaggggaaac uggaagauca aaaggcaaug aauaaauuca uugacgacag ccuuaagaag     1920

cuggauaccu auucuugguc aggauacaaa acuuugacgg ccuauuuuac aaacuacaag     1980

gucgacagua gcaauagggu gaccuacgau gucguguucc acgguuaucu ccccaacgag     2040

ggcgacucca aaaacucucu gccauacggg aagaucaaug gaacuuauaa aggcaccgaa     2100

aaggagaaga uuaaauucuc gagcgagggu uccuuugauc cugacgggaa gaucguuuca     2160

uacgaauggg auuucggcga cggaaacaaa aguaaugagg aaaaccccga gcauucuuau     2220

gauaaggugg gcacauacac cguaaaauua aaggucacug acgauaaggg ggaaagcucc     2280

gugucaacaa cgaccgcuga gauaaaagac cugagcgaga auaagcuacc aguuaucuau     2340

augcacgugc ccaaaucugg agcccucaac cagaaggucg uguuuuacgg uaaaggcacu     2400

uacgauccug acggguccau ugcaggauau cagugggacu ucggcgaugg uagugacuuu     2460

agcucugaac agaauccauc ccauguauac acaaagaaag gggaguauac cgugacacug     2520

cggguuaugg auucaagugg ccaaaugagc gaaaagacua ugaagaucaa aauuaccgac     2580

ccggucuacc ccaucggaac ggagaaggag ccuaacaauu cgaaagaaac cgccuccggc     2640

ccaauagugc ccgggauucc ugugucugga acaaucgaga acacuagcga ucaggacuau     2700

uucuacuuug augucauuac cccaggcgaa guuaagaucg acauaaauaa acuugguuau     2760

gggggagcua cauggguggu guacgaugag aacaauaacg ccguaucaua cgcaacugac     2820

gauggccaga auuugagugg uaaguucaag gcggacaaac ccggccgcua uuacauccac     2880

cuguauaugu uuaacggguc cuacaugccg uauagaauua acaucgaagg aucugucggg     2940

agguga                                                                2946


<210>  5215
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt3) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5215
augaaaagaa agugccugag uaaaagguug auguuagcua uuacaauggc aacuauauuu       60

acggucaaca gcacccugcc caucuaugcc gcgguugaca agaauaacgc uacagccgca      120

cggcgccgac guaaaagagu gcagaaugag uccaagaggu acacuguauc uuaucuaaag      180

acccucaacu acuaugaucu gguggaccuu cuggucaaaa cagaaauuga gaauuugccu      240

gaucucuucc aauacucguc agacgccaag gaauuuuaug gcaacaaaac ccggaugagc      300

uucaucaugg augagauugg gcgcagagcu ccacaguaca cugaaaucga ccacaaggga      360

auaccgacac ugguggaggu ugugagggca gguuuuuacc ugggcuucca uaauaaagag      420

cucaacgaaa ucaauaagcg gaguuuuaag gagcgcguca uucccuccau cuuagccauu      480

cagaaaaacc cuaauuucaa gcuggggacc gaagugcagg auaaaaucgu aucugcuacg      540

ggacuuuugg ccggcaacga gacugcgcca cccgagguug ugaauaacuu uaccccuaua      600

cugcaagacu guauuaagaa uaucgaucga uaugcacuag acgaucucaa aagcaaggcc      660

cuguucaacg uccuugcugc cccaacauac gacauuacug aauaucugag agcaaccaaa      720

gagaagcccg aaaacacacc uugguacggu aagaucgaug gguuuaucaa ugaguugaaa      780

aagcucgcuc uguauggaaa aauuaacgac aauaacuccu ggauaaucga caauggcauu      840

uaccacaucg ccccauuagg caagcugcau ucaaacaaua aaauagggau ugaaacccuc      900

acggagguga ugaaggugua uccguaccuu aguaugcagc aucugcagag cgcggaucag      960

aucaagaggc acuacgacuc uaaagaugcc gagggaaaca agauccccuu ggacaaauuc     1020

aagaaagaag guaaggagaa guauugcccu aaaacuuaca cauucgauga cggcaagguc     1080

auuaucaaag caggggcucg gguugaagag gaaaagguga aacgucuaua uugggccucc     1140

aaggagguaa auucacaauu uuuccgcgug uacggaauug auaagccacu ggaggaaggc     1200

aaccccgacg auauacucac cauggucauc uauaauagcc cugaggaaua caaacugaac     1260

agugugcuuu augguuacga cacuaauaac gggggaaugu acauugagcc agaaggcaca     1320

uuuuucaccu augagagaga ggcucaggaa ucuacguaca cccuggagga auuguuuagg     1380

cacgaguaua cacacuaccu ccagggccgg uaugccguuc ccgggcagug gggacgaacu     1440

aagcuguacg auaaugaccg cuuaaccugg uaugaggaag guggcgcaga gcuguucgcc     1500

ggguccacaa gaacuagcgg aauccuaccg aggaaaucga ucgugucuaa cauucauaac     1560

accacacgga auaaccgcua caagcucucc gacaccgucc acucaaaaua cggcgcuagu     1620

uuugaguucu auaauuacgc guguauguuu auggauuaua uguacaacaa ggacaugggu     1680

auacugaaua aacuuaacga uuuggcaaag aauaacgacg uggaugggua ugacaauuac     1740

aucagagauc ugagcuccaa cuaugcccuc aaugacaagu accaagauca uaugcaggaa     1800

aggauugaca acuacgaaaa ucugacugua ccuuucguug cugaugacua ucuugugcgu     1860

cacgccuaca aaaaccccaa ugagaucuau ucugagauua gcgaagucgc aaagcugaaa     1920

gaugccaagu cagaggugaa aaagagucag uacuuuucca cguucacauu gcggggcagc     1980

uauaccggag gcgcuucuaa ggggaaacuc gaagaccaaa aggccaugaa caaauuuauc     2040

gacgauucac ugaagaaauu agacacuuac aguuggagcg gauauaagac ccugacagca     2100

uacuucacca acuacaaggu cgauuccucu aaucgaguga cuuaugacgu uguguuccac     2160

gguuaccuac caaacgaggg cgauucgaaa aauagccucc cuuaugggaa gauaaacgga     2220

acauacaaag gcacggaaaa ggagaaaauc aaguuuuccu cagaggguag uuucgacccc     2280

gaugggaaga uuguaucuua ugaaugggac uuuggcgaug gaaauaaaag caacgaggaa     2340

aauccagagc auuccuacga caaggucggc accuauacug ugaaacugaa gguuacagau     2400

gacaaagggg aaucaagcgu gucuaccaca acugcggaga ucaaggaucu uuccgagaac     2460

aaauugcccg ucauuuacau gcacgugccu aagaguggag cucugaauca gaagguagug     2520

uucuacggua aaggcaccua ugacccagac gggagcaucg ccggauacca gugggauuuu     2580

ggcgacgguu cugauuucuc cucagaacag aacccgaguc auguuuauac gaagaaaggg     2640

gaguacaccg ucacacucag agugauggac agcucgggcc aaauguccga aaagacuaug     2700

aaaauaaaga uuaccgaucc cguguauccu aucggaacag agaaggagcc aaauaacucu     2760

aaagaaacug caagcggccc cauugucccu gggaucccag uuucaggaac cauagagaau     2820

acgagugacc aggauuacuu uuauuucgac gugaucacac ccggcgaagu gaagauugau     2880

aucaacaaac uggguuacgg gggagccacc uggguagucu acgacgagaa uaacaacgcu     2940

guguccuaug ccacugauga cggccagaau uuaucuggua aguuuaaagc agacaagccg     3000

ggcagguacu auauucaccu guacauguuc aacgggagcu auaugccuua ccgcaucaau     3060

auagaaggau ccguuggccg guga                                            3084


<210>  5216
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5216
aucgccaaca ccaacagcga gaaguacgac uucgaguacc ugaacggccu gagcuacacc       60

gagcugacca accugaucaa gaacaucaag uggaaccaga ucaacggccu guucaacuac      120

agcaccggca gccagaaguu cuucggcgac aagaacagag ugcaggccau caucaacgcc      180

cugcaggaga gcggcagaac cuacaccgcc aacgacauga agggcaucga gaccuucacc      240

gaggugcuga gagccggcuu cuaccugggc uacuacaacg acggccugag cuaccugaac      300

gacagaaacu uccaggacaa gugcaucccc gccaugaucg ccauccagaa gaaccccaac      360

uucaagcugg gcaccgccgu gcaggacgag gugaucacca gccugggcaa gcugaucggc      420

aacgccagcg ccaacgccga gguggugaac aacugcgugc ccgugcugaa gcaguucaga      480

gagaaccuga accaguacgc ccccgacuac gugaagggca ccgccgugaa cgagcugauc      540

aagggcaucg aguucgacuu cagcggcgcc gccuacgaga aggacgugaa gaccaugccc      600

ugguacggca agaucgaccc cuucaucaac gagcugaagg cccugggccu guacggcaac      660

aucaccagcg ccaccgagug ggccagcgac gugggcaucu acuaccugag caaguucggc      720

cuguacagca ccaacagaaa cgacaucgug cagagccugg agaaggccgu ggacauguac      780

aaguacggca agaucgccuu cguggccaug gagagaauca ccugggacua cgacggcauc      840

ggcagcaacg gcaagaaggu ggaccacgac aaguuccugg acgacgccga gaagcacuac      900

cugcccaaga ccuacaccuu cgacaacggc accuucauca ucagagccgg cgacaaggug      960

agcgaggaga agaucaagag acuguacugg gccagcagag aggugaagag ccaguuccac     1020

agaguggugg gcaacgacaa ggcccuggag gugggcaacg ccgacgacgu gcugaccaug     1080

aagaucuuca acagccccga ggaguacaag uucaacacca acaucaacgg cgugagcacc     1140

gacaacggcg gccuguacau cgagcccaga ggcaccuucu acaccuacga gagaaccccc     1200

cagcagagca ucuucagccu ggaggagcug uucagacacg aguacaccca cuaccugcag     1260

gccagauacc ugguggacgg ccuguggggc cagggccccu ucuacgagaa gaacagacug     1320

accugguucg acgagggcac cgccgaguuc uucgccggca gcaccagaac cagcggcgug     1380

cugcccagaa agagcauccu gggcuaccug gccaaggaca agguggacca cagauacagc     1440

cugaagaaga cccugaacag cggcuacgac gacagcgacu ggauguucua caacuacggc     1500

uucgccgugg cccacuaccu guacgagaag gacaugccca ccuucaucaa gaugaacaag     1560

gccauccuga acaccgacgu gaagagcuac gacgagauca ucaagaagcu gagcgacgac     1620

gccaacaaga acaccgagua ccagaaccac auccaggagc uggccgacaa guaccagggc     1680

gccggcaucc cccuggugag cgacgacuac cugaaggacc acggcuacaa gaaggccagc     1740

gagguguaca gcgagaucag caaggccgcc agccugacca acaccagcgu gaccgccgag     1800

aagagccagu acuucaacac cuucacccug agaggcaccu acaccggcga gaccagcaag     1860

ggcgaguuca aggacuggga cgagaugagc aagaagcugg acggcacccu ggagagccug     1920

gccaagaaca gcuggagcgg cuacaagacc cugaccgccu acuucaccaa cuacagagug     1980

accagcgaca acaaggugca guacgacgug guguuccacg gcgugcugac cgacaacgcc     2040

gacaucagca acaacaaggc ccccaucgcc aaggugaccg gccccagcac cggcgccgug     2100

ggcagaaaca ucgaguucag cggcaaggac agcaaggacg aggacggcaa gaucgugagc     2160

uacgacuggg acuucggcga cggcgccacc agcagaggca agaacagcgu gcacgccuac     2220

aagaaggccg gcaccuacaa cgugacccug aaggugaccg acgacaaggg cgccaccgcc     2280

accgagagcu ucaccaucga gaucaagaac gaggacacca ccacccccau caccaaggag     2340

auggagccca acgacgacau caaggaggcc aacggcccca ucguggaggg cgugaccgug     2400

aagggcgacc ugaacggcag cgacgacgcc gacaccuucu acuucgacgu gaaggaggac     2460

ggcgacguga ccaucgagcu gcccuacagc ggcagcagca acuucaccug gcugguguac     2520

aaggagggcg acgaccagaa ccacaucgcc agcggcaucg acaagaacaa cagcaaggug     2580

ggcaccuuca agagcaccaa gggcagacac uacguguuca ucuacaagca cgacagcgcc     2640

agcaacauca gcuacagccu gaacaucaag ggccugggca acgagaagcu gaaggagaag     2700

gagaacaacg acagcagcga caaggccacc gugaucccca acuucaacac caccaugcag     2760

ggcagccugc ugggcgacga cagcagagac uacuacagcu ucgaggugaa ggaggagggc     2820

gaggugaaca ucgagcugga caagaaggac gaguucggcg ugaccuggac ccugcacccc     2880

gagagcaaca ucaacgacag aaucaccuac ggccaggugg acggcaacaa ggugagcaac     2940

aaggugaagc ugagacccgg caaguacuac cugcuggugu acaaguacag cggcagcggc     3000

aacuacgagc ugagagugaa caaguga                                         3027


<210>  5217
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5217
augaagaaga acauccugaa gauccugaug gacagcuaca gcaaggagag caagauccag       60

accgugagaa gagugaccag cgugagccug cuggccgugu accugaccau gaacaccagc      120

agccuggugc uggccaagcc caucgagaac accaacgaca ccagcaucaa gaacguggag      180

aagcugagaa acgcccccaa cgaggagaac agcaagaagg uggaggacag caagaacgac      240

aagguggagc acgugaagaa caucgaggag gccaaggugg agcagguggc ccccgaggug      300

aagagcaaga gcacccugag aagcgccagc agaagaagaa gaaagagaau cgccaacacc      360

aacagcgaga aguacgacuu cgaguaccug aacggccuga gcuacaccga gcugaccaac      420

cugaucaaga acaucaagug gaaccagauc aacggccugu ucaacuacag caccggcagc      480

cagaaguucu ucggcgacaa gaacagagug caggccauca ucaacgcccu gcaggagagc      540

ggcagaaccu acaccgccaa cgacaugaag ggcaucgaga ccuucaccga ggugcugaga      600

gccggcuucu accugggcua cuacaacgac ggccugagcu accugaacga cagaaacuuc      660

caggacaagu gcauccccgc caugaucgcc auccagaaga accccaacuu caagcugggc      720

accgccgugc aggacgaggu gaucaccagc cugggcaagc ugaucggcaa cgccagcgcc      780

aacgccgagg uggugaacaa cugcgugccc gugcugaagc aguucagaga gaaccugaac      840

caguacgccc ccgacuacgu gaagggcacc gccgugaacg agcugaucaa gggcaucgag      900

uucgacuuca gcggcgccgc cuacgagaag gacgugaaga ccaugcccug guacggcaag      960

aucgaccccu ucaucaacga gcugaaggcc cugggccugu acggcaacau caccagcgcc     1020

accgaguggg ccagcgacgu gggcaucuac uaccugagca aguucggccu guacagcacc     1080

aacagaaacg acaucgugca gagccuggag aaggccgugg acauguacaa guacggcaag     1140

aucgccuucg uggccaugga gagaaucacc ugggacuacg acggcaucgg cagcaacggc     1200

aagaaggugg accacgacaa guuccuggac gacgccgaga agcacuaccu gcccaagacc     1260

uacaccuucg acaacggcac cuucaucauc agagccggcg acaaggugag cgaggagaag     1320

aucaagagac uguacugggc cagcagagag gugaagagcc aguuccacag aguggugggc     1380

aacgacaagg cccuggaggu gggcaacgcc gacgacgugc ugaccaugaa gaucuucaac     1440

agccccgagg aguacaaguu caacaccaac aucaacggcg ugagcaccga caacggcggc     1500

cuguacaucg agcccagagg caccuucuac accuacgaga gaacccccca gcagagcauc     1560

uucagccugg aggagcuguu cagacacgag uacacccacu accugcaggc cagauaccug     1620

guggacggcc uguggggcca gggccccuuc uacgagaaga acagacugac cugguucgac     1680

gagggcaccg ccgaguucuu cgccggcagc accagaacca gcggcgugcu gcccagaaag     1740

agcauccugg gcuaccuggc caaggacaag guggaccaca gauacagccu gaagaagacc     1800

cugaacagcg gcuacgacga cagcgacugg auguucuaca acuacggcuu cgccguggcc     1860

cacuaccugu acgagaagga caugcccacc uucaucaaga ugaacaaggc cauccugaac     1920

accgacguga agagcuacga cgagaucauc aagaagcuga gcgacgacgc caacaagaac     1980

accgaguacc agaaccacau ccaggagcug gccgacaagu accagggcgc cggcaucccc     2040

cuggugagcg acgacuaccu gaaggaccac ggcuacaaga aggccagcga gguguacagc     2100

gagaucagca aggccgccag ccugaccaac accagcguga ccgccgagaa gagccaguac     2160

uucaacaccu ucacccugag aggcaccuac accggcgaga ccagcaaggg cgaguucaag     2220

gacugggacg agaugagcaa gaagcuggac ggcacccugg agagccuggc caagaacagc     2280

uggagcggcu acaagacccu gaccgccuac uucaccaacu acagagugac cagcgacaac     2340

aaggugcagu acgacguggu guuccacggc gugcugaccg acaacgccga caucagcaac     2400

aacaaggccc ccaucgccaa ggugaccggc cccagcaccg gcgccguggg cagaaacauc     2460

gaguucagcg gcaaggacag caaggacgag gacggcaaga ucgugagcua cgacugggac     2520

uucggcgacg gcgccaccag cagaggcaag aacagcgugc acgccuacaa gaaggccggc     2580

accuacaacg ugacccugaa ggugaccgac gacaagggcg ccaccgccac cgagagcuuc     2640

accaucgaga ucaagaacga ggacaccacc acccccauca ccaaggagau ggagcccaac     2700

gacgacauca aggaggccaa cggccccauc guggagggcg ugaccgugaa gggcgaccug     2760

aacggcagcg acgacgccga caccuucuac uucgacguga aggaggacgg cgacgugacc     2820

aucgagcugc ccuacagcgg cagcagcaac uucaccuggc ugguguacaa ggagggcgac     2880

gaccagaacc acaucgccag cggcaucgac aagaacaaca gcaagguggg caccuucaag     2940

agcaccaagg gcagacacua cguguucauc uacaagcacg acagcgccag caacaucagc     3000

uacagccuga acaucaaggg ccugggcaac gagaagcuga aggagaagga gaacaacgac     3060

agcagcgaca aggccaccgu gauccccaac uucaacacca ccaugcaggg cagccugcug     3120

ggcgacgaca gcagagacua cuacagcuuc gaggugaagg aggagggcga ggugaacauc     3180

gagcuggaca agaaggacga guucggcgug accuggaccc ugcaccccga gagcaacauc     3240

aacgacagaa ucaccuacgg ccagguggac ggcaacaagg ugagcaacaa ggugaagcug     3300

agacccggca aguacuaccu gcugguguac aaguacagcg gcagcggcaa cuacgagcug     3360

agagugaaca aguga                                                      3375


<210>  5218
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5218
gugcagaacg agagcaagag auacaccgug agcuaccuga agacccugaa cuacuacgac       60

cugguggacc ugcuggugaa gaccgagauc gagaaccugc ccgaccuguu ccaguacagc      120

agcgacgcca aggaguucua cggcaacaag accagaauga gcuucaucau ggacgagauc      180

ggcagaagag ccccccagua caccgagauc gaccacaagg gcauccccac ccugguggag      240

guggugagag ccggcuucua ccugggcuuc cacaacaagg agcugaacga gaucaacaag      300

agaagcuuca aggagagagu gauccccagc auccuggcca uccagaagaa ccccaacuuc      360

aagcugggca ccgaggugca ggacaagauc gugagcgcca ccggccugcu ggccggcaac      420

gagaccgccc cccccgaggu ggugaacaac uucaccccca uccugcagga cugcaucaag      480

aacaucgaca gauacgcccu ggacgaccug aagagcaagg cccuguucaa cgugcuggcc      540

gcccccaccu acgacaucac cgaguaccug agagccacca aggagaagcc cgagaacacc      600

cccugguacg gcaagaucga cggcuucauc aacgagcuga agaagcuggc ccuguacggc      660

aagaucaacg acaacaacag cuggaucauc gacaacggca ucuaccacau cgccccccug      720

ggcaagcugc acagcaacaa caagaucggc aucgagaccc ugaccgaggu gaugaaggug      780

uaccccuacc ugagcaugca gcaccugcag agcgccgacc agaucaagag acacuacgac      840

agcaaggacg ccgagggcaa caagaucccc cuggacaagu ucaagaagga gggcaaggag      900

aaguacugcc ccaagaccua caccuucgac gacggcaagg ugaucaucaa ggccggcgcc      960

agaguggagg aggagaaggu gaagagacug uacugggcca gcaaggaggu gaacagccag     1020

uucuucagag uguacggcau cgacaagccc cuggaggagg gcaaccccga cgacauccug     1080

accaugguga ucuacaacag ccccgaggag uacaagcuga acagcgugcu guacggcuac     1140

gacaccaaca acggcggcau guacaucgag cccgagggca ccuucuucac cuacgagaga     1200

gaggcccagg agagcaccua cacccuggag gagcuguuca gacacgagua cacccacuac     1260

cugcagggca gauacgccgu gcccggccag uggggcagaa ccaagcugua cgacaacgac     1320

agacugaccu gguacgagga gggcggcgcc gagcuguucg ccggcagcac cagaaccagc     1380

ggcauccugc ccagaaagag caucgugagc aacauccaca acaccaccag aaacaacaga     1440

uacaagcuga gcgacaccgu gcacagcaag uacggcgcca gcuucgaguu cuacaacuac     1500

gccugcaugu ucauggacua cauguacaac aaggacaugg gcauccugaa caagcugaac     1560

gaccuggcca agaacaacga cguggacggc uacgacaacu acaucagaga ccugagcagc     1620

aacuacgccc ugaacgacaa guaccaggac cacaugcagg agagaaucga caacuacgag     1680

aaccugaccg ugcccuucgu ggccgacgac uaccugguga gacacgccua caagaacccc     1740

aacgagaucu acagcgagau cagcgaggug gccaagcuga aggacgccaa gagcgaggug     1800

aagaagagcc aguacuucag caccuucacc cugagaggca gcuacaccgg cggcgccagc     1860

aagggcaagc uggaggacca gaaggccaug aacaaguuca ucgacgacag ccugaagaag     1920

cuggacaccu acagcuggag cggcuacaag acccugaccg ccuacuucac caacuacaag     1980

guggacagca gcaacagagu gaccuacgac gugguguucc acggcuaccu gcccaacgag     2040

ggcgacagca agaacagccu gcccuacggc aagaucaacg gcaccuacaa gggcaccgag     2100

aaggagaaga ucaaguucag cagcgagggc agcuucgacc ccgacggcaa gaucgugagc     2160

uacgaguggg acuucggcga cggcaacaag agcaacgagg agaaccccga gcacagcuac     2220

gacaaggugg gcaccuacac cgugaagcug aaggugaccg acgacaaggg cgagagcagc     2280

gugagcacca ccaccgccga gaucaaggac cugagcgaga acaagcugcc cgugaucuac     2340

augcacgugc ccaagagcgg cgcccugaac cagaaggugg uguucuacgg caagggcacc     2400

uacgaccccg acggcagcau cgccggcuac cagugggacu ucggcgacgg cagcgacuuc     2460

agcagcgagc agaaccccag ccacguguac accaagaagg gcgaguacac cgugacccug     2520

agagugaugg acagcagcgg ccagaugagc gagaagacca ugaagaucaa gaucaccgac     2580

cccguguacc ccaucggcac cgagaaggag cccaacaaca gcaaggagac cgccagcggc     2640

cccaucgugc ccggcauccc cgugagcggc accaucgaga acaccagcga ccaggacuac     2700

uucuacuucg acgugaucac ccccggcgag gugaagaucg acaucaacaa gcugggcuac     2760

ggcggcgcca ccuggguggu guacgacgag aacaacaacg ccgugagcua cgccaccgac     2820

gacggccaga accugagcgg caaguucaag gccgacaagc ccggcagaua cuacauccac     2880

cuguacaugu ucaacggcag cuacaugccc uacagaauca acaucgaggg cagcgugggc     2940

agauga                                                                2946


<210>  5219
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt4) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5219
augaagagaa agugccugag caagagacug augcuggcca ucaccauggc caccaucuuc       60

accgugaaca gcacccugcc caucuacgcc gccguggaca agaacaacgc caccgccgcc      120

agaagaagaa gaaagagagu gcagaacgag agcaagagau acaccgugag cuaccugaag      180

acccugaacu acuacgaccu gguggaccug cuggugaaga ccgagaucga gaaccugccc      240

gaccuguucc aguacagcag cgacgccaag gaguucuacg gcaacaagac cagaaugagc      300

uucaucaugg acgagaucgg cagaagagcc ccccaguaca ccgagaucga ccacaagggc      360

auccccaccc ugguggaggu ggugagagcc ggcuucuacc ugggcuucca caacaaggag      420

cugaacgaga ucaacaagag aagcuucaag gagagaguga uccccagcau ccuggccauc      480

cagaagaacc ccaacuucaa gcugggcacc gaggugcagg acaagaucgu gagcgccacc      540

ggccugcugg ccggcaacga gaccgccccc cccgaggugg ugaacaacuu cacccccauc      600

cugcaggacu gcaucaagaa caucgacaga uacgcccugg acgaccugaa gagcaaggcc      660

cuguucaacg ugcuggccgc ccccaccuac gacaucaccg aguaccugag agccaccaag      720

gagaagcccg agaacacccc cugguacggc aagaucgacg gcuucaucaa cgagcugaag      780

aagcuggccc uguacggcaa gaucaacgac aacaacagcu ggaucaucga caacggcauc      840

uaccacaucg ccccccuggg caagcugcac agcaacaaca agaucggcau cgagacccug      900

accgagguga ugaaggugua ccccuaccug agcaugcagc accugcagag cgccgaccag      960

aucaagagac acuacgacag caaggacgcc gagggcaaca agaucccccu ggacaaguuc     1020

aagaaggagg gcaaggagaa guacugcccc aagaccuaca ccuucgacga cggcaaggug     1080

aucaucaagg ccggcgccag aguggaggag gagaagguga agagacugua cugggccagc     1140

aaggagguga acagccaguu cuucagagug uacggcaucg acaagccccu ggaggagggc     1200

aaccccgacg acauccugac cauggugauc uacaacagcc ccgaggagua caagcugaac     1260

agcgugcugu acggcuacga caccaacaac ggcggcaugu acaucgagcc cgagggcacc     1320

uucuucaccu acgagagaga ggcccaggag agcaccuaca cccuggagga gcuguucaga     1380

cacgaguaca cccacuaccu gcagggcaga uacgccgugc ccggccagug gggcagaacc     1440

aagcuguacg acaacgacag acugaccugg uacgaggagg gcggcgccga gcuguucgcc     1500

ggcagcacca gaaccagcgg cauccugccc agaaagagca ucgugagcaa cauccacaac     1560

accaccagaa acaacagaua caagcugagc gacaccgugc acagcaagua cggcgccagc     1620

uucgaguucu acaacuacgc cugcauguuc auggacuaca uguacaacaa ggacaugggc     1680

auccugaaca agcugaacga ccuggccaag aacaacgacg uggacggcua cgacaacuac     1740

aucagagacc ugagcagcaa cuacgcccug aacgacaagu accaggacca caugcaggag     1800

agaaucgaca acuacgagaa ccugaccgug cccuucgugg ccgacgacua ccuggugaga     1860

cacgccuaca agaaccccaa cgagaucuac agcgagauca gcgagguggc caagcugaag     1920

gacgccaaga gcgaggugaa gaagagccag uacuucagca ccuucacccu gagaggcagc     1980

uacaccggcg gcgccagcaa gggcaagcug gaggaccaga aggccaugaa caaguucauc     2040

gacgacagcc ugaagaagcu ggacaccuac agcuggagcg gcuacaagac ccugaccgcc     2100

uacuucacca acuacaaggu ggacagcagc aacagaguga ccuacgacgu gguguuccac     2160

ggcuaccugc ccaacgaggg cgacagcaag aacagccugc ccuacggcaa gaucaacggc     2220

accuacaagg gcaccgagaa ggagaagauc aaguucagca gcgagggcag cuucgacccc     2280

gacggcaaga ucgugagcua cgagugggac uucggcgacg gcaacaagag caacgaggag     2340

aaccccgagc acagcuacga caaggugggc accuacaccg ugaagcugaa ggugaccgac     2400

gacaagggcg agagcagcgu gagcaccacc accgccgaga ucaaggaccu gagcgagaac     2460

aagcugcccg ugaucuacau gcacgugccc aagagcggcg cccugaacca gaagguggug     2520

uucuacggca agggcaccua cgaccccgac ggcagcaucg ccggcuacca gugggacuuc     2580

ggcgacggca gcgacuucag cagcgagcag aaccccagcc acguguacac caagaagggc     2640

gaguacaccg ugacccugag agugauggac agcagcggcc agaugagcga gaagaccaug     2700

aagaucaaga ucaccgaccc cguguacccc aucggcaccg agaaggagcc caacaacagc     2760

aaggagaccg ccagcggccc caucgugccc ggcauccccg ugagcggcac caucgagaac     2820

accagcgacc aggacuacuu cuacuucgac gugaucaccc ccggcgaggu gaagaucgac     2880

aucaacaagc ugggcuacgg cggcgccacc uggguggugu acgacgagaa caacaacgcc     2940

gugagcuacg ccaccgacga cggccagaac cugagcggca aguucaaggc cgacaagccc     3000

ggcagauacu acauccaccu guacauguuc aacggcagcu acaugcccua cagaaucaac     3060

aucgagggca gcgugggcag auga                                            3084


<210>  5220
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5220
auugcuaaca caaauuccga gaaauaugac uuugaauacc uuaacggccu gucuuauacg       60

gagcucacca aucugaucaa gaacauuaaa uggaaucaga ucaacgggcu uuucaauuac      120

agcacaggau cccaaaaguu uuucggcgau aaaaacagag uccaggccau uaucaaugcg      180

cugcaggaau cugggcggac cuauacagcu aacgacauga agggaaucga gaccuuuaca      240

gaaguucucc gcgccggcuu cuaccugggg uauuacaaug auggacugag cuaccucaac      300

gacagaaauu uucaggauaa gugcauuccc gccaugaucg cuauucagaa aaacccuaau      360

uucaagcugg gcaccgccgu gcaagacgag gugaucacgu cccuuggcaa acugauuggg      420

aacgcuagcg ccaacgcgga ggucgugaau aacuguguuc cggugcucaa gcaguuucgg      480

gaaaaucuga accaguaugc ccccgauuac gucaaaggaa ccgcugugaa ugagcuuauc      540

aagggcauug aguucgacuu uucuggggcc gcuuaugaaa aggauguuaa aacaaugccu      600

ugguacggaa agaucgaccc cuucaucaac gagcugaaag cccucggccu guaugggaau      660

auuaccuccg cgacagaaug ggccagcgau gugggaaucu acuaucuguc uaaguucggc      720

cucuacucca ccaaccgcaa ugacauuguc caaagccugg agaaagcugu ggauauguac      780

aaguauggca aaaucgccuu uguggcuaug gaaagaauua cgugggacua cgacgggauc      840

ggaucuaacg gcaagaaggu cgaucacgac aaauuccuug augacgccga gaagcauuau      900

cugccuaaaa cauacaccuu ugauaauggg acauucauca uucgggccgg agacaagguu      960

uccgaagaga aaaucaagcg ccucuauugg gcuagcagag aggugaaguc ccaguuucac     1020

cggguggucg gcaacgauaa agcgcuggaa guggggaaug ccgacgaugu ucuuaccaug     1080

aagauuuuca acucucccga ggaauacaaa uuuaauacca acaucaacgg agugagcaca     1140

gacaauggcg gccuguauau ugagccucgc gggacguucu acaccuacga aagaacaccg     1200

cagcagucca ucuuuagccu cgaggagcug uuccggcaug aauauaccca cuaccugcaa     1260

gcucgcuauc ucgucgaugg acuguggggc caggggcccu uuuacgagaa gaacagacuu     1320

acaugguucg acgaaggaac cgccgaguuu uucgccggcu cuacgcggac auccggggug     1380

cugccucgca aaagcauccu cggcuaucug gcuaaggaca agguugauca uagauacucu     1440

cuuaaaaaga cccugaauag cggauaugac gauuccgacu ggauguucua caacuacggc     1500

uuugccgugg cgcacuaucu cuacgaaaaa gauaugccca ccuucauuaa gaugaauaaa     1560

gcuauccuga acacagacgu caagucuuau gaugagauua ucaagaaacu gagcgacgau     1620

gccaauaaga acaccgagua ccagaaucac auucaagaac ucgccgacaa auaucagggg     1680

gcuggaaucc cucugguguc cgaugacuac cuuaaggauc auggcuauaa aaaggccagc     1740

gaggucuacu cugaaauuuc caaagcugcc agccugacaa acacgucugu gaccgcggag     1800

aagucccagu acuuuaauac auucacccuc cgggggacau auaccggaga gacgagcaag     1860

ggcgaauuua aagacuggga cgagaugucc aagaaacugg augggacccu ggaaucucuu     1920

gccaagaaca gcugguccgg cuacaaaaca cucaccgcuu auuucacaaa uuacagaguu     1980

accucugaca acaaggugca guaugauguc guguuucacg gaguucugac ggacaaugcc     2040

gauaucagca acaacaaggc ucccaucgcc aaagugacag gcccguccac cggggcgguc     2100

ggacgcaaua uugaguucag cggcaaggac ucuaaagaug aagacgggaa gaucgugucc     2160

uacgauuggg acuuuggaga uggcgccaca agccggggga aaaacucugu gcaugcuuau     2220

aagaaggccg gcaccuacaa uguuacccug aaagucacag acgauaaggg agcuacggcc     2280

accgaguccu ucacaauuga gaucaaaaac gaagacacca caaccccuau uacgaaggag     2340

auggaaccca augacgauau caaagaggcc aacggcccua ucguggaagg ggugacaguc     2400

aagggagacc ucaauggcag cgaugacgcu gauaccuuuu acuucgacgu gaaggaggau     2460

ggggacguua ccauugagcu gcccuauucu ggaagcucca acuuuacaug gcuuguguac     2520

aaagaaggcg augaccaaaa ucacaucgcg agcgggauug auaagaacaa uucuaaaguc     2580

ggcaccuuca aguccacaaa aggaagacac uauguguuca ucuacaagca ugacagcgcc     2640

uccaacauuu cuuauagccu gaauaucaaa ggccucggga acgagaagcu gaaggaaaaa     2700

gagaauaacg acuccucuga uaaggcuacg guuaucccca acuuuaauac cacaaugcag     2760

ggaagccugc uuggcgacga uucccgcgac uacuauucuu ucgaagugaa agaggagggg     2820

gaagucaaca uugagcucga uaagaaagac gaauuuggag ugaccuggac acugcacccu     2880

gagagcaaua ucaacgaucg gauuaccuac ggccagguug acggcaauaa gguguccaac     2940

aaggucaaac ugagaccggg gaaguacuau cuccuggugu acaaauauag cggaucuggc     3000

aauuacgagc uucgcgugaa caaguga                                         3027


<210>  5221
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5221
augaaaaaga acauucuuaa aauccugaug gacuccuauu cuaaggagag caaaauucag       60

acagucagac ggguuacguc cgugucucuc cuggcugugu accuuaccau gaauacaagc      120

ucccuggucc ucgccaagcc caucgaaaac accaaugaua caagcauuaa gaacguggag      180

aaacugcgca augcgccuaa cgaagaaaau ucuaagaaag uugaagacuc caagaacgau      240

aaaguggagc acgucaagaa uaucgaggaa gcuaaggugg agcaaguugc cccggaagug      300

aaaagcaagu cuacccugag auccgccagc cggcgcagac ggaaacgcau cgcuaacaca      360

aauucugaga aguaugacuu ugaguaccuc aacggccugu ccuauaccga acuuacgaau      420

cugauuaaaa acaucaagug gaaucagauu aacggacucu ucaacuacag caccggaucc      480

cagaaauuuu ucggcgauaa gaauagaguc caggccauca uuaacgcucu gcaagagucu      540

gggcggacau auaccgccaa ugacaugaag ggaaucgaaa cauuuaccga ggugcuucgc      600

gcgggcuucu accuggggua cuauaacgau ggacucagcu accugaauga cagaaacuuu      660

caggauaaau gcauucccgc caugaucgcu auccagaaga auccuaacuu caaacugggc      720

acggccgugc aggacgaagu cauuacaucc cucggcaagc ugaucgggaa ugcuagcgcc      780

aacgcggagg uugugaauaa cugugugccc guccuuaaac aauuucggga gaaucugaac      840

caguaugccc cugauuacgu gaagggaacc gcuguuaaug aacucauuaa gggcaucgag      900

uucgacuuuu cuggggccgc uuaugaaaaa gaugugaaga caaugcccug guacggaaaa      960

auugacccuu ucaucaacga gcugaaggcc cuuggccugu augggaacau caccuccgcc     1020

accgaauggg cuagcgacgu cggaauuuac uaccucucua aauucggccu guauagcaca     1080

aaucgcaacg auaucgugca gucccuggag aaggcgguug acauguacaa guauggcaaa     1140

auugccuuug uggcuaugga gagaaucacg ugggauuacg acgggauugg aucuaauggc     1200

aagaaagucg aucaugacaa guuccucgau gacgccgaaa aacacuaucu gccgaagacc     1260

uacacauuug auaacgggac cuucaucauc cgggccggag acaaggugag cgaggaaaag     1320

auuaagcgcc uuuauugggc uuccagagag gucaaaagcc aguuucaucg ggugguuggc     1380

aaugauaagg cccuggaagu ggggaacgcg gacgacgucc ucacaaugaa aaucuucaau     1440

ucucccgagg aguacaaguu uaacaccaau auuaacggag uguccacgga uaauggcggc     1500

cuguacaucg aaccuagagg gacauucuau accuacgagc gcacacccca acagagcauu     1560

uuuagccuug aggagcuguu ccggcacgag uauacccauu accuccaggc uagauaucug     1620

guugacggac uguggggcca agggccuuuu uacgagaaaa accgccucac cugguucgau     1680

gaaggaacag ccgaauuuuu cgccggcucc acgcggacca gcggggugcu gcccagaaag     1740

uccauccuug gcuaucuggc uaaggacaaa gucgaucacc gcuacucucu caagaaaaca     1800

cugaauagcg gauacgacga uuccgacugg auguucuaua acuacggcuu ugccguggcu     1860

cacuaucugu acgagaagga uaugccgacc uucauuaaaa ugaauaaggc cauccuuaac     1920

acagacguga agucuuauga ugaaaucauu aaaaagcuca gcgacgaugc gaacaaaaau     1980

accgaguacc agaaccauau ccaggagcug gccgacaagu aucagggggc ugggauuccu     2040

cugguuuccg acgauuaccu caaagaccac ggcuacaaga aggccagcga agucuauucu     2100

gagaucucca aagcugccag ccugacgaau accucuguga cagcggaaaa gucccaauac     2160

uuuaacaccu ucacacuucg ggggaccuau acgggagaga caagcaaagg cgaauuuaag     2220

gauugggacg agaugucuaa aaagcuggau gggacccucg agagccuggc caaaaauucc     2280

uggagcggcu acaaaacacu gaccgcuuau uucaccaacu acagagugac aucugacaau     2340

aagguccagu augauguggu uuuucaugga gugcuuacgg acaacgccga uauuuccaau     2400

aacaaagcuc ccaucgccaa ggucaccggc ccuagcacag gggccguggg acgcaauauc     2460

gaguucuccg gcaaagacuc uaaggaugaa gacgggaaaa uuguuagcua cgauugggac     2520

uuuggagacg gcgcuaccuc ccgggggaag aacucugugc acgcguacaa gaaagccggc     2580

acauauaaug ucacccucaa ggugacggau gacaaaggag cuacagccac cgaaucuuuc     2640

accaucgaga uuaagaacga agauacaacc acacccauca cgaaagagau ggagcccaau     2700

gacgauauua aggaagccaa cggcccuauc guugaggggg ugaccgucaa gggagaccug     2760

aacggcuccg augacgcuga uacauuuuac uucgacguga aagaagaugg ggacgugacc     2820

aucgagcugc cguauucugg aagcuccaau uuuacauggc ucgucuacaa ggagggcgac     2880

gaucagaacc acauugccag cgggaucgac aaaaauaacu cuaagguugg caccuucaaa     2940

uccacgaagg gaagacauua uguguucauu uacaagcacg auagcgcguc uaauaucucc     3000

uauagccuga acauuaaagg ccuugggaau gaaaagcuga aagagaagga aaacaaugac     3060

ucuuccgaua aagcuaccgu gauccccaac uuuaauacaa ccaugcaggg aagccuccug     3120

ggcgacgauu cccgcgacua cuacagcuuc gaggucaagg aagaggggga ggugaacauc     3180

gaacuggaua agaaagacga guuuggaguu acauggaccc uucauccuga aucuaauauu     3240

aacgaucgga ucacauaugg ccaaguggac ggcaauaagg ucagcaacaa agugaagcuc     3300

agacccggga aauacuaucu gcugguuuac aaguauuccg gaucuggcaa uuacgagcuc     3360

cgggugaaca aguga                                                      3375


<210>  5222
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5222
guccagaacg aguccaaaag auauacaguu ucuuaccuua agacgcugaa uuauuacgac       60

cucguggauc ugcuugugaa aaccgaaauu gagaaccugc ccgaccucuu ucaauauagc      120

uccgaugcua aggaguucua cggcaauaaa acacggaugu cuuuuaucau ggacgaaauu      180

gggcgcagag ccccucagua uaccgaaauc gaucacaagg gcauuccgac acuggucgag      240

gugguucggg cgggauucua ccugggguuu cauaacaagg agcucaauga aaucaacaaa      300

cgcagcuuca aggagagagu gauccccucc auucuggcua uccagaaaaa uccuaacuuu      360

aagcugggaa ccgaagucca ggacaaaauu gugagcgcca caggccugcu cgccgggaau      420

gagaccgcuc ccccugaggu ugugaacaau uucacgccca uccugcaaga uugcauuaag      480

aacaucgacc gguacgcccu ugaugaccug aagucuaaag cucucuuuaa uguccuggcc      540

gcgccuaccu augauauuac agaauaccug cgcgccacca aggagaaacc ggaaaacaca      600

cccugguaug gaaagaucga cggcuucauc aaugagcuca aaaagcuggc ucuuuacggc      660

aaaauuaacg auaacaauuc cuggaucauu gacaacggga ucuaucacau ugccccucug      720

ggaaagcucc auagcaauaa caagaucggc aucgaaaccc ugacggaggu gaugaaagug      780

uaccccuauc uuucuaugca gcaccuucag uccgcugacc agauuaagag acauuacgau      840

agcaaagacg ccgaggggaa uaagaucccu cucgauaaau uuaagaagga aggaaaagag      900

aaguacuguc ccaaaacaua uaccuucgac gauggcaagg ucauuaucaa agcgggggcc      960

cggguugaag aggaaaaggu gaagcgccug uacugggcuu cuaaagaggu gaacucccaa     1020

uucuuuagag ucuauggaau ugacaagccg cuggaggaag gcaauccuga ugacauccuc     1080

acaaugguga ucuacaacag ccccgaggaa uauaaacuua auuccguucu uuacggcuau     1140

gauaccaaca augggggaau guacauugag ccugaaggca ccuucuuuac auacgagcgg     1200

gaggcccagg aaucuacgua uacccuggag gaacucuucc gccacgagua cacacacuau     1260

cugcagggga gauacgcugu gcccggacag uggggccgga ccaagcugua ugacaacgau     1320

cgccugacau gguacgagga agggggagcc gagcucuuug ccggcagcac cagaacgucc     1380

ggcauccugc cccggaaaag cauugucucu aauauccaua acacaaccag aaauaaccgc     1440

uauaagcugu ccgacaccgu gcacagcaag uacggggcuu cuuucgaauu uuacaacuau     1500

gcgugcaugu ucauggacua cauguauaau aaagauaugg gcauucucaa caagcugaau     1560

gaccuugcca aaaacaauga uguugacgga uacgauaacu auauccggga ccugagcucc     1620

aauuacgcuc ucaacgauaa guaucaagac cauaugcagg agagaauuga uaauuacgaa     1680

aaccugacag ugccuuuugu cgccgacgau uaccuggugc gccacgccua uaaaaauccg     1740

aacgagaucu acucugagau cagcgaaguc gcuaaacuua aggacgccaa guccgaggug     1800

aagaaaagcc aguauuucuc uaccuuuaca cuccgggggu ccuacacggg aggcgcgagc     1860

aaggggaaac uggaagauca aaaggcuaug aauaaauuca uugacgacuc ucugaagaag     1920

cucgauaccu auuccuggag cggcuacaaa acacugaccg ccuauuuuac aaacuacaag     1980

guugacuccu cuaauagagu gaccuacgau gucguguucc acggauaucu ucccaacgag     2040

ggcgacagca aaaacucccu gccuuacggg aagaucaaug gaacguauaa aggcaccgaa     2100

aaggagaaga uuaaauucuc uagcgagggg uccuuugauc ccgacggaaa gaucguuagc     2160

uacgaauggg auuucggcga cgggaacaaa ucuaaugagg aaaacccuga gcauuccuau     2220

gauaaggugg gcacauacac cgucaaacuc aaggugacag acgauaaggg agaaagcucu     2280

guguccacca cgacagccga gauuaaagac cugagcgaga auaagcugcc cguuaucuau     2340

augcacgucc cgaaaucugg cgcucuuaac cagaaggugg uguuuuacgg gaaaggaacc     2400

uacgauccug acggcagcau cgccggguau cagugggacu ucggagaugg cuccgacuuu     2460

agcucugaac agaaucccuc ccaugucuac acaaagaaag gggaguauac cgugacccuc     2520

cgcguuaugg auagcuccgg ccaaaugucu gaaaagacaa ugaagauuaa aaucacggac     2580

ccuguguacc ccauuggaac cgagaaggag ccuaacaaua gcaaagaaac agcuuccggc     2640

cccaucgucc cggggauucc ugugucugga accaucgaga acacaagcga ucaggacuau     2700

uucuacuuug auguuaucac ccccggcgaa gugaagauug acaucaauaa acugggguau     2760

ggaggcgcca cgugggucgu guacgaugag aacaauaacg cgguuuccua cgccacagac     2820

gaugggcaga aucugucugg caaguucaag gcugacaaac ccggacggua uuacauucac     2880

cucuauaugu uuaacggcag cuacaugccu uauagaauca acauugaagg guccguggga     2940

cgcuga                                                                2946


<210>  5223
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt5) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5223
augaaaagaa agugccuuuc caaacggcug augcucgcua uuacaauggc cacgaucuuu       60

accgucaacu cuacacugcc cauuuaugcg gcuguugaca agaauaacgc caccgccgcu      120

cgcagacggc gcaaaagagu gcagaaugag agcaagcggu acacaguguc cuaucuuaag      180

acccugaacu acuaugaucu cgucgaccug cuggugaaaa cagaaaucga gaaucucccu      240

gaucuguucc aauacucuag cgacgccaag gaauuuuaug gcaacaaaac ccgcaugucc      300

uucauuaugg augagaucgg gagacgggcu ccgcaguaca cggaaaucga ccacaagggc      360

auucccaccc uuguugaggu gguccgcgcc ggauuuuacc ugggguucca uaauaaagag      420

cucaacgaaa ucaauaagag auccuuuaag gagcggguga uuccuucuau ccuggcgauu      480

cagaaaaacc ccaauuucaa acuuggaaca gaaguucagg auaagaucgu guccgccacc      540

ggccugcucg cugggaacga gacagccccu cccgaggucg ugaauaacuu uaccccuauu      600

cugcaagacu guaucaagaa uaucgaucgc uaugcucugg acgaucucaa aagcaaggcc      660

cuguucaacg ugcuugcggc cccgacguac gacauuacag aauaucugag agcuaccaaa      720

gagaagcccg aaaacacacc uugguacgga aagaucgaug gcuuuauuaa ugagcucaaa      780

aagcuggccc uuuauggcaa aaucaacgac aauaacucuu ggauuaucga caaugggauc      840

uaccacauug cuccccuggg aaagcuccau uccaacaaua aaaucggcau ugaaacccug      900

accgagguca ugaagguuua uccuuaccug agcaugcagc accuccaguc ugccgaucag      960

aucaagcggc auuacgacuc caaagaugcc gaggggaaca agauuccccu ggacaaauuc     1020

aagaaagaag gaaaggagaa guauugcccg aaaacauaca cguucgauga cggcaaggug     1080

aucaucaaag cuggggcgcg cguggaagag gaaaagguca aaagacuuua uugggccagc     1140

aaggagguga auagccaauu uuuccggguu uacggaauug auaagccucu ggaggaaggc     1200

aaccccgacg auauccucac cauggugauu uauaauucuc cugaggaaua caaacugaac     1260

agcguccuuu auggcuacga cacaaauaac gggggaaugu acaucgagcc cgaaggcacc     1320

uuuuucacau augagagaga ggcucaggaa uccaccuaca cgcuggagga acucuuucgc     1380

cacgaguaua cacacuaccu gcaggggcgg uaugccgugc ccggacagug gggcagaacc     1440

aagcuguacg auaaugaccg ccucaccugg uaugaggaag ggggagccga gcuguucgcu     1500

ggcagcacac ggaccucugg cauucuuccu agaaaaucca ucguuagcaa cauucauaac     1560

acaacgcgca auaaccggua caagcugucu gacaccgugc acagcaaaua cggggccucc     1620

uuugaguucu auaauuacgc guguauguuu auggauuaua uguacaacaa ggacauggga     1680

auccucaaua aacugaacga ucuggcuaag aauaacgacg ucgauggcua ugacaauuac     1740

aucagagauc uuucuagcaa cuaugcccuc aaugacaagu accaagauca uaugcaggaa     1800

cgcauugaca acuacgaaaa ucugacagug ccguucgucg ccgaugacua ucuggugcgg     1860

cacgcuuaca aaaaccccaa ugagaucuau uccgagauua gcgaaguugc caagcucaaa     1920

gaugcuaagu cugaggugaa aaagucccag uacuuuagca ccuucacacu gagagggucu     1980

uauaccggag gcgccuccaa ggggaaacuu gaagaccaaa aggcgaugaa caaauuuauc     2040

gacgauagcc ugaagaaacu cgacacguac uccuggucug gcuauaagac ccugacagcc     2100

uacuucacca acuacaaggu cgauagcucc aaucgcguga cauaugacgu uguguuccac     2160

ggauaccugc cuaacgaggg cgauucuaaa aauagccuuc ccuaugggaa gauuaacgga     2220

accuacaaag gcacggaaaa ggagaaaauc aaguuuucca gcgagggguc uuucgacccu     2280

gauggaaaga ucgucuccua ugaaugggac uuuggcgaug ggaauaaaag caacgaggaa     2340

aaucccgagc auucuuacga caaggugggc acauauaccg ugaaacucaa gguuacagau     2400

gacaaaggag aauccagcgu cucuaccacc acagcugaga uuaaggaucu gagcgagaac     2460

aaacugccgg ugaucuacau gcacgugccu aaguccggcg cccucaauca gaaggucgug     2520

uucuacggga aaggaacgua ugaccccgac ggcagcauug cuggguacca gugggauuuu     2580

ggagacggcu cugauuucuc cagcgaacag aacccuuccc auguuuauac caagaaaggg     2640

gaguacacag ugacccugcg ggucauggac ucuagcggcc aaauguccga aaagacaaug     2700

aaaaucaaga uuaccgaucc cguguauccu aucggaacgg agaaggagcc caauaacucu     2760

aaagaaacag ccagcggccc gaucguuccu gggauucccg uguccggaac caucgagaau     2820

accucugacc aggauuacuu uuauuucgac gucauuacac ccggcgaagu gaagaucgau     2880

auuaacaaac uuggguacgg aggcgcgacc uggguugugu acgacgagaa uaacaacgcc     2940

gucagcuaug cuacagauga cgggcagaau cuguccggca aguuuaaagc cgacaagccu     3000

ggaagauacu auauccaccu cuacauguuc aacggcagcu auaugccgua ccggaucaau     3060

auugaagggu cugugggacg cuga                                            3084


<210>  5224
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5224
auagcaaaua caaauuccga aaaauaugac uucgaauacc uaaacggucu uaguuacaca       60

gaauuaacua accuaauuaa aaacauaaaa uggaaucaaa uaaauggcuu auuuaauuau      120

ucaacaggua gucaaaaauu cuucggagau aaaaacagag ugcaagcaau aauaaacgcc      180

cuacaagagu caggacgaac auauacagca aaugacauga aaggaauaga gacauucaca      240

gagguauuac gugccggauu cuaccuagga uacuacaacg acgguuuauc uuacuuaaau      300

gacagaaacu uccaggauaa auguauacca gcaaugauag caauacagaa aaacccuaau      360

uucaaacucg gaacggcggu ucaagacgaa guaauuacau cuuuagguaa auugauagga      420

aacgcaucag cgaacgccga gguaguaaac aauugcguac cgguccuuaa acaauuuaga      480

gaaaaucuaa accaauaugc accagacuac gugaaaggaa cagcagugaa ugaauuaaua      540

aaaggcauug aguucgacuu cucaggagca gcauaugaaa aagauguaaa aacaaugcca      600

ugguacggaa aaauagaucc auucauaaau gaacuaaaag cauuaggauu auacggcaac      660

aucaccagug caacugaaug ggcaucagau gucgggauau acuauuuauc aaaauucgga      720

cucuauagca caaaccgaaa cgacauagua caaucacuag agaaagcagu agacauguac      780

aaauacggga aaauagcauu uguagccaug gaacgaauua caugggacua cgauggcaua      840

gguagcaaug gaaagaaagu agaucacgau aaauuccuug acgacgcaga aaaacacuau      900

cuuccuaaaa cauacacuuu ugauaacggu accuucauaa uacgagccgg ugauaaagua      960

agcgaagaga aaauaaaaag gcuauauugg gcaagcagag aagucaaaag ccaauuucau     1020

agaguaguag gaaaugacaa agcacuagaa guuggaaacg cugacgaugu ucuaacaaug     1080

aaaaucuuca acucaccuga agaauacaaa uucaacacaa acauaaaugg aguaaguacc     1140

gacaacggag gauuauauau agaacccagg gggacguuuu auaccuacga gagaaccccu     1200

caacaaucua uauuuuccuu agaagaauua uuucgacaug aauacacaca cuauuuacaa     1260

gcacgauauu ugguagaugg acuaugggga caaggaccau uuuaugagaa aaacagacuu     1320

acgugguucg acgaaggaac ggcagaguuc uuugcaggaa guacaagaac aaguggagua     1380

uuaccaagaa aaucaauacu agguuacuua gcaaaagaca aaguagauca cagauacagc     1440

cuaaagaaaa cacugaauag cgguuaugau gacagugauu ggauguucua uaauuacgga     1500

uucgcaguag cucacuaucu auaugaaaaa gauaugccaa cauucaucaa aaugaauaaa     1560

gcaauacuua acaccgacgu uaaaucauau gacgaaauaa uaaagaaauu aagugacgac     1620

gcaaacaaaa auaccgaaua ccaaaaccac auccaagaac uagcagacaa auaucaaggu     1680

gcaggaauac cauuaguauc agacgacuac cucaaagacc auggauacaa gaaagcgucc     1740

gaaguauacu cagaaauaag uaaagcagca ucauugacua auacuucagu aacagcagaa     1800

aaaucacaau acuuuaacac auucacacuu cgcggaacau auacgggaga aaccucaaaa     1860

ggugaauuua aagauuggga cgaaaugagu aaaaagcucg acggcacucu agaaucauug     1920

gcuaaaaacu ccuggucagg auauaaaaca cuaacagccu acuucaccaa uuacagaguc     1980

accucagaua auaaaguaca auaugacgua guauuucaug gagucuuaac agacaacgcu     2040

gauauaagua acaauaaagc gccuauagcg aaaguaacag gaccaucaac gggagcagua     2100

ggaagaaaua uugaguucuc aggaaaggau agcaaagacg aagacggaaa aauuguaucu     2160

uaugauuggg auuucggaga uggagcaacc ucaagaggga aaaacagugu gcaugccuac     2220

aagaaagcag gaacuuauaa uguaacacua aaagugacag augacaaagg agcgacagca     2280

acagagagcu ucacgauuga aauuaaaaac gaagauacua caacacccau aacaaaagaa     2340

auggaaccaa augaugacau aaaagaagca aacggaccga uaguggaagg cguaacggua     2400

aaaggagacu uaaauggaag ugaugacgcc gacacauuuu acuuugaugu uaaagaagac     2460

ggugauguca caauagaauu acccuacucu gguaguucca acuucacuug guuaguauac     2520

aaagaaggag augaucaaaa ucauauagca uccggaauag acaaaaacaa uagcaaagua     2580

ggcacauuua aauccacaaa aggacgucau uauguuuuca uuuacaaaca cgauagugca     2640

aguaacauaa guuauucucu aaauauaaaa ggacuaggua augaaaaacu aaaagaaaaa     2700

gaaaacaacg auagcaguga caaagcuacu guuaucccaa acuucaacac cacaaugcaa     2760

ggcagcuuac ucggagacga uucacgagau uauuacagcu ucgaaguaaa agaagagggg     2820

gaaguaaaca uagaacuaga uaagaaagac gaauuuggag uaacauggac acuacacccg     2880

gaaucgaaca uaaaugacag aaucacauau ggacaaguag acggaaacaa aguaucaaau     2940

aaagucaaac uaagaccugg caaauauuac cuauuagugu auaaauauuc aggaucaggu     3000

aauuacgaac ugagagucaa uaaauaa                                         3027


<210>  5225
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5225
augaagaaaa acauacuaaa aauacucaug gauuccuaua gcaaagaaag uaaaauacaa       60

acaguacgga gaguuacauc aguaagucua uuagcaguau accuaacaau gaauacaagc      120

uccuuaguau uagcaaagcc aaucgaaaac acaaacgaua cgucaauuaa aaacguagaa      180

aaauuacgaa acgcaccuaa ugaagaaaac ucaaagaaag ucgaagacag caaaaacgau      240

aaagucgagc acgugaaaaa uauagaagaa gcaaaaguag aacaaguagc cccagaagua      300

aaaaguaaau caacucuaag aucugcuuca cgcagacgac guaaacgaau agccaacaca      360

aauucagaaa aauaugauuu cgaauaccua aacggguuau cauacacaga gcuaacgaau      420

cuaaucaaaa acauaaaaug gaaccaaaua aauggccuau uuaauuauag cacaggaucc      480

caaaaauucu ucggcgacaa aaaucgagua caagcaauaa uuaaugcacu acaggaaucu      540

ggcagaacau auacugcuaa ugacaugaaa ggaauagaaa cauuuacaga aguacucaga      600

gcaggauuuu auuuagguua uuauaaugac ggcuuaaguu accuaaauga uagaaacuuu      660

caagauaaau gcauaccugc aaugaucgca auacagaaaa acccaaacuu uaaacuaggg      720

acagcgguac aagacgaagu aauaaccagc uuaggaaaac ucaucggaaa cgcuucugca      780

aacgcggaag uuguaaacaa cugcguacca guacuaaaac aauuccgaga aaaccuaaau      840

caauacgcuc cagauuaugu aaaaggaacg gcuguaaacg aauuaauaaa agguaucgaa      900

uuugauuuca gcggcgcagc cuaugaaaag gacgucaaaa cgaugccaug guauggaaaa      960

auagacccau ucauaaauga acugaaagca cucggacuuu acgguaauau aacaagugcu     1020

acagaauggg caucagacgu aggaauauau uauuuaucaa aauucggauu auacucaaca     1080

aauagaaaug acauaguaca aagucuagaa aaagcggucg acauguacaa auauggcaaa     1140

auagcauuug uagcuaugga acgcauaaca ugggacuaug auggaauagg uucuaacggu     1200

aagaaaguug aucaugauaa auucuuagau gacgcagaaa aacacuacuu accaaaaaca     1260

uauacauucg acaacggcac cuuuauaaua cgugccggag acaaaguuag ugaagagaaa     1320

auuaaacgac uauacugggc uucgagagaa guaaaaucuc aauuucacag agucguggga     1380

aacgauaaag cacuagaagu uggaaacgca gaugaugucc ucacaaugaa aaucuuuaau     1440

uccccggaag aauacaaauu uaauacgaau aucaacggcg ugucaacuga uaauggagga     1500

cuguauauag aaccacgagg aacauucuac acuuaugaaa gaaccccgca acaaagcauu     1560

uucucccuag aagaacuauu caggcaugaa uauacacauu accuccaagc cagauaccua     1620

guugauggac uauggggaca aggaccguuu uacgagaaaa aucgauuaac cugguuugau     1680

gaaggaacgg cagaguucuu ugcaggauca acaagaacaa gcggaguacu accaagaaaa     1740

uccauacuag guuacuuagc aaaagauaaa guugaccaca gauauaguuu aaagaaaacc     1800

cucaacagug guuacgauga uucggauugg auguuuuaca acuacggauu cgcaguugcg     1860

cacuacuuau acgaaaaaga uaugccaacg uucauaaaaa ugaacaaagc aauacuaaau     1920

acugauguca aaagcuacga ugaaauaaua aagaaacuaa gugacgacgc caauaaaaau     1980

acagaauacc aaaaccauau acaagaacua gcugacaaau accaaggugc gggaauaccu     2040

cuaguaagug acgacuaucu aaaagaucau ggauauaaga aagcaucaga aguuuacucu     2100

gaaaucagca aagccgcauc auuaacaaac accucaguaa cagcugaaaa aucacaauau     2160

uucaacacau ucacacuaag ggguacauau acaggcgaaa ccaguaaagg agaauuuaaa     2220

gauugggacg aaaugagcaa gaaauuagau ggaacucuag aaucuuuagc caaaaacucu     2280

uggucaggau acaaaacauu aacggcauau uucacgaacu auagaguuac aagugauaau     2340

aaagugcaau augacguagu auuucacgga guccucacag auaacgccga uauuucaaau     2400

aauaaagcuc cgauagcuaa aguaaccggu ccauccacag gagcaguagg cagaaacauu     2460

gaguucucug guaaagauag uaaagaugaa gauggaaaaa uagucucaua cgacugggau     2520

uucggagaug gagcaacauc aagagggaaa aacucaguac augccuauaa gaaagcggga     2580

accuauaacg uaacccuaaa agucacagau gacaagggag caacggcuac agaaaguuuu     2640

acaaucgaaa uuaaaaauga agacacaaca acaccaauaa cgaaggaaau ggaaccaaac     2700

gacgacauca aagaagcuaa cggaccaaua guugaaggag uaacaguuaa aggagauuua     2760

aacggaucag augaugcgga cacuuuuuac uucgauguca aagaagaugg agacgucacc     2820

auugaauuac cuuauucagg aagcaguaac uucaccuggu uaguauauaa agaaggagac     2880

gaucaaaacc acaucgcuag cggcauagau aaaaauaauu caaagguugg aaccuuuaag     2940

ucaacaaaag gaagacacua uguauuuauc uacaaacaug auuccgccuc aaacauaucc     3000

uauagccuga auaucaaagg ccuaggaaac gaaaaauuaa aagaaaaaga aaauaacgac     3060

agcucagaua aagcaacagu aauuccuaac uuuaacacua caaugcaagg uagccuauug     3120

ggugacgaua guagagacua uuacagcuuu gaagucaaag aagaaggaga aguuaauaua     3180

gaacuagaca agaaagauga guuuggagua accuggacau ugcacccuga auccaauaua     3240

aaugacagaa uuacuuaugg ccaagucgac ggaaauaaag ucucaaacaa agugaaacua     3300

agaccgggua aauauuaccu uuugguguac aaauauagug gcucaggaaa cuaugaauua     3360

agggucaaca aauga                                                      3375


<210>  5226
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5226
guacagaacg aaucaaaaag auacacagua aguuacuuaa aaacguuaaa cuacuacgac       60

cuaguagauu uauuagucaa aaccgaaauu gaaaauuuac ccgaccuuuu ccaauacucu      120

uccgaugcaa aagaauuuua cggcaauaaa acacgaauga gcuucauaau ggaugaaauc      180

gguagacgag cuccccaaua cacagaaaua gaccacaaag gaaucccuac auuaguugaa      240

guaguuagag caggauucua ccuagguuuu cauaacaagg aauuaaauga aauaaauaaa      300

cgaucauuca aagaacgagu aauaccauca auacuugcaa uacagaaaaa cccaaacuuu      360

aaacuuggaa cugaaguuca agacaaaaua gugucagcaa caggacuccu agcuggcaau      420

gaaacagcuc caccagaagu aguaaacaac uuuacaccaa uauuacaaga uugcauuaaa      480

aauauagacc gcuacgcuuu agaugaucua aaaaguaaag cacuauuuaa cguacuggca      540

gcaccuacuu acgacauaac cgaauaccua cgagcaacaa aagaaaaacc ugaaaacacc      600

cccugguacg gaaaaauaga cggauuuauc aacgaacuaa agaaauuagc acuuuaugga      660

aaaauuaacg auaauaauuc cuggaucauc gacaauggca uauaccauau agcuccacua      720

ggaaaauuac acucaaacaa caaaauagga auagaaacac uaacggaggu aaugaaagua      780

uacccauauc uaucaaugca acaccuacaa ucagccgauc aaauaaaaag acauuaugac      840

ucaaaagaug cagaaggcaa caaaauacca cuagacaaau ucaagaaaga aggaaaagaa      900

aaauauuguc cgaaaacaua caccuuugau gauggaaaag uaauuauaaa agcuggagca      960

agagucgaag aagaaaaagu uaaacgauua uauugggcau caaaagaagu aaauagucaa     1020

uuuuuccgcg ucuauggaau agauaaaccc cuugaggaag gaaauccaga cgacauccua     1080

acaaugguaa uauauaauuc accugaagaa uacaaauuaa auucaguacu auauggauac     1140

gacacaaaca acggaggaau guacauagaa ccagaaggua cauucuuuac auaugagaga     1200

gaagcacaag aaagcacaua cacucuagaa gaacuauuca gacacgagua cacccacuac     1260

cuacaagguc gauaugcugu accaggacaa uggggaagga caaaacuaua cgauaaugac     1320

agacuaaccu gguacgaaga aggaggagcc gaacuauucg caggaagcac acguacauca     1380

gguauacuac caagaaaauc cauagucagc aacauacaua acacgacacg uaacaacaga     1440

uacaaauuaa gugacacagu ucauagcaaa uauggagcuu cauuugaguu uuauaacuac     1500

gcauguaugu ucauggauua cauguacaac aaagacaugg gaaucuuaaa uaaacuaaac     1560

gauuuagcua aaaauaauga uguagaugga uacgacaacu auauacgcga uuuaagcagu     1620

aacuacgcac uaaacgauaa auaccaagau cacaugcaag aaaggauaga caacuacgaa     1680

aauuuaacag ucccauucgu cgcagacgau uaccuaguca gacacgccua uaaaaauccu     1740

aacgaaauau acucagagau uagcgagguc gcaaaauuaa aagacgcaaa aagugaagua     1800

aagaaaaguc aauauuucag uacauuuacc uuaagaggcu cauauacagg cggagcaagu     1860

aaaggaaaau uagaagauca aaaagcaaug aauaaauuca uugaugacag ccuaaagaaa     1920

uuagacacau acucaugguc gggcuacaaa acccuuaccg cuuacuuuac aaacuauaaa     1980

gucgacaguu caaacagggu cacauacgac guuguauucc acggcuacuu accaaaugaa     2040

ggagacagua aaaacucccu accauacgga aaaauaaaug gaacguauaa aggaacagaa     2100

aaagagaaaa uaaaauucuc aucagaagga ucauucgacc cggacggaaa aauuguuucc     2160

uacgaauggg acuucgggga cgguaacaaa ucgaacgaag aaaauccuga acauucauau     2220

gauaaaguag gaacauacac aguaaaacua aaagucacag augacaaagg agaaucgucc     2280

guaucuacca caacagcgga aauaaaagau uuaucagaaa auaaacuacc cguuauuuac     2340

augcaugucc caaaaagcgg agcauuaaac caaaaaguag uauuuuacgg aaaaggcaca     2400

uaugauccag acggaucaau ugccgguuau caaugggacu ucggagacgg aagcgacuuc     2460

aguagugaac aaaaccccuc ccauguauac acaaagaaag gugaauacac agucaccuua     2520

agaguaaugg acucaucagg acagaugagu gagaaaacaa ugaaaauaaa aauaaccgac     2580

cccgucuauc caauaggaac cgaaaaagaa ccaaauaauu caaaagaaac agcaucagga     2640

ccaauaguac ccggcauccc aguaucuggc accaucgaaa acaccucuga ucaagacuac     2700

uucuacuucg acguaauaac accaggugaa guaaaaauug auaucaauaa acuaggauac     2760

ggcggagcaa cauggguagu uuacgacgaa aacaacaacg caguuagcua cgcuacagau     2820

gacggacaaa accuaagugg gaaauuuaaa gcagacaaac cuggaagaua uuauauccau     2880

cucuacaugu ucaacgguuc uuauaugcca uauagaauaa acauagaagg cucaguagga     2940

agauaa                                                                2946


<210>  5227
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt6) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5227
augaaaagaa aauguuuauc caaaagacua augcuagcua ucacaauggc uacaauuuuc       60

acagugaacu cuacauuacc aauauacgcu gcaguugaua aaaacaacgc aacagccgcu      120

agaagaagaa gaaaacgagu acaaaacgaa agcaaaagau acaccgucuc uuacuuaaaa      180

acacuaaauu acuacgaucu gguagaccuu cuaguaaaaa cugaaauaga aaaucuacca      240

gacuuauucc aauauucaag cgacgcaaaa gaauuuuacg gaaacaagac aagaaugagu      300

uuuauuaugg augaaauugg acguagagca ccccaauaca ccgaaauaga ucacaaaggc      360

auacccaccu uaguggaagu uguaagagcc ggguucuacu uaggauuuca uaauaaagaa      420

uuaaaugaaa uaaauaaacg auccuucaaa gaaagaguca uaccaagcau ucucgcaauu      480

cagaaaaacc caaauuucaa acuaggaacc gaaguacaag auaaaauugu aucagcaacc      540

ggauuauuag cugguaacga aacagcuccc ccugaaguag uaaauaacuu uacccccaua      600

uuacaagauu gcauuaaaaa uauagacaga uacgccuuag acgaccuaaa aucaaaagca      660

cuauucaaug uccucgcugc uccaacauau gacauaacag aauaccuuag agcgacuaag      720

gaaaaacccg aaaacacccc augguauggu aaaauagaug guuucauaaa cgaacuaaag      780

aaacucgcac uauacggaaa aauaaacgac aacaauagcu ggauaauaga caauggaaua      840

uaucauauag caccauuagg aaaacuacau ucaaacaaua aaaucggaau agaaacauua      900

acagaaguaa ugaaaguaua ucccuauuua agcaugcaac aucuacaguc ugcggaccaa      960

auaaaacguc auuacgacuc uaaagacgca gaaggaaaca aaauuccacu agacaaauuu     1020

aagaaagaag ggaaagaaaa auacugccca aaaaccuaca cuuuugauga uggaaaagua     1080

auuauaaaag cuggagcacg cguagaagaa gaaaaaguaa aacgauuaua cugggccagu     1140

aaagaaguga auagucaauu cuucagaguc uauggaauug acaaaccucu agaagaaggc     1200

aacccagacg auauacuaac caugguuaua uauaauucuc cagaagaaua caaacuaaau     1260

ucaguauuau acggauauga uaccaacaac ggagggaugu acauagaacc ugaagguacu     1320

uucuuuacau acgaaagaga agcacaagaa agcacauaua ccuuagagga acuauuuaga     1380

cacgaauaua cacacuaccu gcaaggaaga uaugcugugc caggacaaug gggacguacu     1440

aaacuauacg acaacgauag acuaacaugg uaugaagaag gaggagcaga acucuuugcu     1500

ggcuccacca gaacaagugg aaucuuacca agaaaaagua uaguaucaaa cauacauaac     1560

acaacaagaa auaacagaua caaacucagc gacacaguac acucaaaaua cggagcuagc     1620

uucgaauuuu auaauuacgc augcauguuc auggacuaca uguacaacaa agauauggga     1680

aucuuaaaca aacuaaauga ucuagcgaaa aauaaugaug uugaugguua cgacaacuau     1740

auccgugauc ucucaucaaa cuacgcacug aacgacaaau accaagauca uaugcaagaa     1800

cguauagaua auuaugaaaa uuuaacugua cccuucguag cagaugauua cuugguuagg     1860

caugcauaca aaaauccuaa ugaaauauac ucagaaauau cugaaguagc caaacuaaaa     1920

gaugcaaaaa gugaaguuaa gaaaagccaa uauuuuucca cauuuacauu acgaggaucc     1980

uauacuggag gggccaguaa agguaaacua gaagaccaaa aagcaaugaa caaauucauc     2040

gaugauuccc uaaagaaauu agauacauau aguuggucag gcuacaaaac acuaacagcc     2100

uauuuuacaa auuacaaagu agauucaagc aauagaguua cauacgacgu aguauuccau     2160

gguuauuuac caaaugaagg cgacaguaaa aauucauuac cauacggaaa aauaaaugga     2220

acauauaaag gaacggaaaa agagaaaaua aaauucuccu cugaaggauc cuuugaccca     2280

gacggaaaaa ucguuagcua cgaaugggac uucggugaug guaacaaauc aaacgaagaa     2340

aacccugaac acagcuacga caaaguagga accuacacag ucaaacucaa aguaacagau     2400

gauaaaggug aaucuucugu uucuacgaca acagcagaaa ucaaagauuu auccgaaaac     2460

aaacucccag ucauauauau gcacguacca aaaucaggug cacuuaauca aaagguugua     2520

uuuuauggaa aagguacaua ugaucccgac ggaucaaucg caggauacca augggacuuc     2580

ggagacgggu cagauuucuc cucugaacaa aacccaagcc acguauacac caagaaagga     2640

gaauauaccg uaaccuuacg agucauggau aguucagguc aaaugucaga gaaaacaaug     2700

aaaaucaaaa uaacugaucc aguauaccca aucggaacag aaaaagaacc aaauaauagc     2760

aaagaaacag caaguggacc caucgugcca ggcaucccag uaucgggcac aauagaaaau     2820

acgagcgacc aagacuauuu cuacuuugac gucauaacac caggagaagu aaaaaucgau     2880

auaaauaaac uaggauacgg aggagccaca ugggucgucu acgaugaaaa caacaaugcc     2940

gugagcuaug caacagacga uggacagaau cuuucuggga aauucaaagc agauaaacca     3000

ggacgauacu auauacacuu auacauguuu aaugguaguu acaugccaua ccgaauaaac     3060

auugaaggaa gcguuggaag auga                                            3084


<210>  5228
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5228
auugcaaaca cuaauuccga gaaauaugac uuugaauacu ugaacggccu gaguuauacc       60

gagcucacga aucugaucaa gaacauuaaa uggaaucaga ucaacggguu guucaauuac      120

agcacugguu cccaaaaguu uuucggcgau aaaaacaggg uccaggccau uaucaaugcg      180

cugcaggaaa gcgggcggac cuauaccgcc aacgacauga agggcaucga gacuuuuacc      240

gaagugcucc gcgcagguuu cuaccugggg uauuacaaug auggccuguc cuaccucaac      300

gacaggaauu uucaggauaa gugcauuccc gccaugaucg caauucagaa aaacccaaau      360

uucaagcugg gcacggccgu acaggacgag gugaucacua gcuuggggaa acugauuggu      420

aacgcgagcg ccaacgcaga ggucgugaau aacugugugc cgguccucaa gcaguuucgg      480

gaaaaucuga accaguaugc ccccgauuac gugaaaggca ccgccguaaa ugagcugauc      540

aaggggauug aguucgacuu cuccggcgca gccuaugaaa aagaugugaa gacuaugcca      600

ugguacggua agaucgaccc cuuuaucaac gaguugaaag cgcucgggcu guauggcaau      660

auuaccagcg ccaccgaaug ggcaagugau gucggcaucu acuaucuguc caaguucggg      720

cucuacagca cgaaccgcaa ugacauugug caaucccugg agaaagccgu ggauauguac      780

aaguauggua aaaucgcauu ugucgccaug gaaaggauua cuugggacua cgacggcauc      840

gggaguaacg gcaagaaggu ggaucacgac aaauucuugg augacgccga gaagcauuau      900

cugccaaaaa ccuacacuuu ugauaauggu accuucauca uucgggcggg cgacaaggua      960

agcgaagaga aaaucaagcg ccucuauugg gcauccaggg aggugaagag ucaguuucac     1020

cgggucgugg ggaacgauaa agcccuggaa gugggcaaug ccgacgaugu ccugaccaug     1080

aagauuuuca acagucccga ggaauacaaa uuuaauacua acaucaacgg gguguccacg     1140

gacaauggug gcuuguauau ugagccacgc gggaccuucu acacuuacga aaggaccccg     1200

cagcagagca ucuuuagucu cgaggagcug uuccggcaug aauauaccca cuaccugcaa     1260

gcacgcuauc ucguagaugg ccuguggggu cagggccccu uuuacgagaa gaacagguug     1320

acuugguucg acgaagggac ggccgaguuc uuugcgggcu ccacccggac uagcggggug     1380

cugccacgca aaagcauccu cggcuaucug gccaaggaca aggucgauca uagguacucc     1440

cugaaaaaga ccuugaauag ugguuaugac gauagcgacu ggauguucua caacuacggg     1500

uuugcagugg cccacuaucu cuacgaaaaa gauaugccca ccuucauuaa gaugaauaaa     1560

gcaauccuga acacugacgu caaguccuau gaugagauua ucaaaaagcu gagcgacgau     1620

gccaauaaga acacggagua ccagaaucac auucaagaac ucgccgacaa auaucagggc     1680

gcagguaucc cacuggugag ugaugacuac uugaaggauc auggcuauaa aaaggccucc     1740

gagguguaca gcgaaauuuc caaagcggcc agucugacca acacuagcgu aaccgcagag     1800

aagucccagu acuuuaauac uuucacccuc cgggggacgu auaccggcga gacuagcaag     1860

ggggaauuua aagacuggga cgagaugagu aagaaacugg auggcacccu ggaauccuug     1920

gccaagaaca gcugguccgg uuacaaaacu cugaccgccu auuucacgaa uuaccgcgug     1980

accagugaca acaaggucca guaugaugug gucuuucacg gggugcucac ugacaaugca     2040

gauaucagca acaacaaggc gcccaucgcc aaagugaccg gcccguccac uggcgcagua     2100

gggaggaaua uugaguucag cgguaaggac aguaaagaug aagacggcaa gaucgugucc     2160

uacgauuggg acuuugggga uggcgccacc agccggggua aaaacuccgu ccaugccuac     2220

aagaaagcag ggacguauaa ugugacccug aaggucacug acgacaaggg cgccaccgcg     2280

acugagagcu ucaccauuga gaucaaaaac gaagauacga ccacucccau uaccaaggag     2340

auggaaccaa augacgauau caaagaggcc aacggcccca ucguggaagg ggugacugua     2400

aagggugacc ucaauggcag ugaugacgca gauaccuucu acuuugacgu caaagaggau     2460

ggggacguga cuauugagcu gccauauagc ggcuccagua acuucaccug guugguguac     2520

aaggaaggug augaccaaaa ucacaucgcc agcgggauug auaagaacaa uuccaaaguc     2580

ggcacguuua agagcaccaa aggcaggcac uauguguuca ucuacaagca ugacuccgcc     2640

aguaacauua gcuauucccu gaauaucaaa gggcucggua acgagaagcu gaaggaaaaa     2700

gagaauaacg acaguagcga uaaggcaacu gugaucccca acuuuaauac cacuaugcag     2760

ggcucccugu ugggggacga uagccgcgac uacuacaguu ucgaaguaaa agaggagggc     2820

gaagucaaca uugagcugga uaagaaagac gaauuuggug ugaccuggac gcuccaccca     2880

gaguccaaua ucaacgaucg gauuaccuau gggcaagugg acggcaauaa ggucagcaac     2940

aaagugaagc ugaggccggg caaguacuau cuccugguau acaaauauuc cgggagcggu     3000

aauuacgagu ugcgcgugaa caaguga                                         3027


<210>  5229
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5229
augaaaaaga acauuuugaa aauccugaug gacuccuaua guaaggagag caaaauucag       60

acugucaggc gggugaccuc cguaagccuc cuggcagugu acuugacgau gaauacuucc      120

agucuggucc ucgccaagcc caucgaaaac accaaugaua ccagcauuaa gaacguggag      180

aaacugcgca augcgccaaa cgaagaaaau uccaagaaag uggaagacag caagaacgau      240

aaagucgagc acgugaagaa uaucgaggaa gccaaaguag agcaaguggc accggaaguc      300

aagaguaagu ccacucugag gagcgccucc cggcgcaggc ggaaacgcau cgcaaacacc      360

aauagugaga aguaugacuu ugaguaccuc aacggccuga gcuauacgga auugacuaau      420

cugauuaaaa acaucaagug gaaucagauu aacggucucu ucaacuacuc caccgggagc      480

cagaaauuuu ucggcgauaa gaauagggug caggccauca uuaacgcgcu gcaagagagu      540

gggcggacuu auaccgccaa ugacaugaag ggcaucgaaa ccuuuacgga ggugcugcgc      600

gcagguuucu acuuggggua cuauaacgau ggccucuccu accugaauga caggaacuuu      660

caggauaaau gcauucccgc caugaucgcc auccagaaga auccaaacuu caaacugggc      720

acugcagucc aggacgaagu gauuaccagc cucgggaagc ugaucgguaa ugccagugcg      780

aacgccgagg uagugaauaa cugugucccc guguugaaac aauuucggga gaaucugaac      840

caguaugcac cagauuacgu gaagggcacu gccgucaaug aacucauuaa ggggaucgag      900

uucgacuucu ccggcgcagc cuaugaaaaa gaugugaaga ccaugcccug guacgguaaa      960

auugacccau uuaucaacga gcugaaggcc cugggguugu auggcaacau caccagcgcg     1020

acugaauggg caagcgacgu aggcauuuac uaccucucca aauucgggcu guauaguacg     1080

aaucgcaacg auaucgugca gagccuggag aaggccgucg acauguacaa guaugguaaa     1140

auugccuuug uggcaaugga gaggaucacc ugggauuacg acggcauugg guccaauggc     1200

aagaaagucg aucaugacaa guuccucgau gacgccgaaa aacacuaucu gccgaagacu     1260

uacaccuuug auaacgguac cuucaucauc cgggcgggcg acaaagugag cgaggaaaag     1320

auuaagcgcu uguauugggc caguagggag gugaaauccc aguuucaucg gguagugggg     1380

aaugauaagg cacuggaagu cggcaacgcc gacgacgugc ucacuaugaa aaucuucaau     1440

agccccgagg aguacaaguu uaacacgaau auuaacgggg ucuccaccga uaaugguggc     1500

cuguacaucg aaccacgcgg gacuuucuau accuacgaga ggacucccca acagaguauu     1560

uuuagccugg aagaguuguu ccggcacgag uauacccauu accuccaggc aagguaucug     1620

guggacggcc ugugggguca aggcccauuu uacgagaaaa accgccucac gugguucgau     1680

gaggggaccg ccgaguucuu ugccggcucc acucggacca gcggggugcu gcccaggaag     1740

aguaucuugg gcuaucuggc aaaggacaaa guagaucacc gcuacucccu caagaaaacu     1800

cugaauagcg guuacgacga uuccgacugg auguucuaua acuacggguu ugccguggcg     1860

cacuaucugu acgaaaagga uaugccgacc uucauuaaaa ugaauaaggc caucuugaac     1920

acggacguca agaguuauga ugaaaucauu aaaaagcuga gcgacgaugc aaacaaaaau     1980

accgaguacc agaaccauau ccaggagcuc gccgacaagu aucagggcgc cgguauuccc     2040

cugguguccg acgauuaccu caaagaccac ggcuacaaga aagcaagcga agucuauagu     2100

gagaucucca aggcggccag ccugacuaau accuccguga cugcagaaaa gagccaauac     2160

uuuaacaccu ucacguugcg ggggaccuau acuggcgaga ccaguaaagg ggaauuuaag     2220

gauugggacg agaugagcaa aaagcuggau ggcacucucg agucccuggc caaaaauagu     2280

uggagcgguu acaagacccu gacggccuau uucaccaacu acagggugac uuccgacaau     2340

aagguacagu acgaugucgu guuucauggg guguugaccg acaacgcaga uauuagcaau     2400

aacaaagccc caaucgcgaa ggucacuggc cccuccaccg gcgccguggg gcgcaauauc     2460

gaguucagug guaaagacag caaggaugaa gacggcaaaa uuguguccua ugacugggau     2520

uuuggggacg gcgcaacgag ucgggguaag aacagcguac acgccuacaa gaaagccggg     2580

accuauaaug ucacucugaa ggugaccgau gacaaaggcg caacugccac cgaauccuuc     2640

acuaucgaga uuaagaacga agauaccacg accccaauca cuaaagagau ggagcccaau     2700

gacgauauua aggaagcgaa cggcccaauc guggaggggg ucaccgugaa aggugaccuc     2760

aacggcagcg augacgccga uacuuucuac uuugacguaa aggaagaugg ggacgugacc     2820

aucgagcugc cguauagugg cuccagcaau uucacguggc ucgucuacaa ggagggugac     2880

gaucagaacc acauugcauc cgggaucgac aaaaauaaca gcaagguggg caccuuuaaa     2940

aguacuaagg gcaggcauua uguguucauu uacaaacacg auuccgccag caauaucagu     3000

uacucccuga acauuaaggg guuggguaau gaaaagcuga aagagaagga aaacaaugac     3060

agcuccgaua aagcaaccgu cauccccaac uuuaauacua ccaugcaggg cagccugcuc     3120

ggggacgaua gucgggacua uuacagcuuc gaggugaagg aagagggcga gguaaacauu     3180

gaacuggaua aaaaggacga guuuggugug acguggaccu ugcauccaga auccaauauc     3240

aacgaucgca ucacuuaugg gcaagucgac ggcaauaagg ugaguaacaa agugaagcug     3300

aggcccggca aauacuaucu ccuggucuac aaguauagcg gguccgguaa cuacgagcuc     3360

cgggugaaua aauga                                                      3375


<210>  5230
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5230
guccagaacg aguccaaaag guauacugug aguuacuuga agacccugaa uuauuacgac       60

cucguagauc uguuggugaa aacggaaauu gagaaccugc ccgaccucuu ucaauauagc      120

uccgaugcaa aggaguucua cggcaauaaa acucggauga gcuuuaucau ggacgaaauu      180

gggcgcaggg ccccacagua uaccgaaauc gaucacaagg guauuccgac ccuggucgag      240

guggugcggg cgggcuucua ccugggguuu cauaacaagg agcucaauga aaucaacaaa      300

cgcuccuuca aggagagggu cauccccagu auucuggcca uccagaaaaa uccaaacuuu      360

aaguugggca cugaagugca ggacaaaauu guaagcgcaa ccggucugcu cgccgggaau      420

gagacggcac ccccagaggu ggucaacaau uucacuccca uccugcaaga uugcauuaag      480

aacaucgacc gguacgcccu ggaugacuug aaauccaagg cgcucuuuaa ugugcuggcc      540

gcaccaaccu augauauuac ugaauaccug cgcgccacca aggagaaacc ggaaaacacc      600

cccugguaug gcaagaucga cggcuucauc aaugagcuca aaaagcuggc cuuguacggg      660

aaaauuaacg auaacaauag cuggaucauu gacaacggua ucuaucacau ugcaccacug      720

ggcaagcucc auaguaauaa caagaucggg aucgaaacgc ugacugaggu gaugaaaguc      780

uaccccuauc uguccaugca gcacuugcag agcgccgacc agauuaagag gcauuacgau      840

uccaaagacg cggagggcaa uaagauccca cucgauaaau ucaagaagga agguaaagag      900

aaguacuguc ccaaaaccua uacuuuugac gaugggaagg ugauuaucaa agccggcgca      960

cggguagaag aggaaaaggu gaagcgccug uacugggcca guaaagaggu caacagccaa     1020

uucuuuaggg uguauggcau ugacaagccg cuggaggaag ggaaucccga ugacauccuc     1080

accaugguga ucuacaacuc cccagaggaa uauaaacuga auagcgucuu guacgguuau     1140

gauaccaaca auggcgggau guacauugag cccgaaggca cuuucuuuac guacgagcgg     1200

gaggcacagg aaaguaccua uacucuggag gaacucuucc gccacgagua cacccacuau     1260

cugcagggua gguacgccgu gccaggccag ugggggcgga ccaagcugua ugacaacgau     1320

cgcuugacuu gguacgagga aggcggggcc gagcucuuug cggguuccac gaggaccagc     1380

ggcauccugc cccggaaaag uauuguaucc aauauccaua acacuacccg caauaacagg     1440

uauaagcuga gcgacaccgu gcacagcaaa uacggggcau ccuucgaauu uuacaacuau     1500

gccugcaugu ucauggacua cauguauaau aaggauaugg gcauucucaa caagcugaau     1560

gacuuggcca aaaacaauga ugucgacggu uacgauaacu auauccggga ccugaguagc     1620

aauuacgcac ucaacgauaa guaucaagac cauaugcagg agaggauuga uaauuacgaa     1680

aaccugacug ugccauuugu cgccgacgau uaccuggugc gccacgcgua uaaaaauccg     1740

aacgagaucu acuccgagau cagcgaagug gccaaguuga aagacgcaaa gagugaggua     1800

aagaaauccc aguauuucag cacguuuacc cugcggggcu ccuacacugg gggcgccagu     1860

aaggggaaac ucgaagauca aaaggcaaug aauaaauuca uugacgacag ccugaagaag     1920

cucgauaccu auuccuggag cggcuacaaa acucugaccg ccuacuucac gaacuauaag     1980

guggacaguu ccaauagggu caccuacgau guggucuuuc acgguuauuu gcccaacgag     2040

ggggacagca aaaacucccu gccauacggc aagaucaaug guacuuauaa aggcaccgaa     2100

aaggagaaaa uuaaguucag uagcgagggg uccuuugauc ccgacggcaa gaucgugagc     2160

uacgaauggg auuucgggga cggcaacaaa aguaaugagg aaaacccaga gcauuccuau     2220

gauaaggugg guacuuacac cguaaaacuc aaggugacgg acgauaaagg ggaaagcucc     2280

gucagcacca cuaccgccga gauuaaggac cugagugaga auaagcugcc cgugaucuac     2340

augcacgucc cgaaaagcgg cgcauugaac cagaaggugg uguuuuaugg caaagggacu     2400

uacgacccag augguuccau cgccggcuau cagugggacu ucggggaugg cagugacuuu     2460

agcuccgaac agaaucccag ccauguauac accaagaaag gugaguauac ggucacccug     2520

cgcgugaugg auuccagugg gcaaaugagc gaaaagacua ugaagauuaa aaucaccgac     2580

cccguguacc caauuggcac ugagaaggag cccaacaauu ccaaagaaac cgcgaguggc     2640

ccaaucgucc cggggauucc cgugagcggu acgaucgaga acaccuccga ucaggacuau     2700

uucuacuuug augugaucac uccaggcgaa guaaagauug acaucaauaa acucggguac     2760

ggcggugcca ccugggucgu guaugaugag aacaauaacg cagugagcua cgccacugac     2820

gaugggcaga aucugagugg caaguucaaa gccgacaagc ccggccggua uuacauucac     2880

cucuauaugu uuaacggguc cuacaugcca uauaggauca acauugaagg uagcgucggc     2940

cgcuga                                                                2946


<210>  5231
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt7) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5231
augaaaagga agugcuuguc caaacggcug augcucgcaa uuacuauggc caccaucuuu       60

acggucaaca guacucugcc cauuuaugcg gccguggaca agaauaacgc aaccgccgca      120

cgcaggcggc gcaaaagggu acagaaugag agcaagcggu acaccguguc cuauuugaag      180

acucugaacu acuaugaucu cgucgaccug cuggugaaaa ccgaaaucga gaaucuccca      240

gaucuguucc aauacagcuc cgacgccaag gaauuuuaug gcaacaaaac gcgcaugagu      300

uucauuaugg augagaucgg gaggcgggcg ccgcaguaca cugaaaucga ccacaagggu      360

auucccaccu ugguggaggu cgugcgcgcc ggcuuuuacc ugggguucca uaauaaagag      420

cucaacgaaa ucaauaagag gagcuuuaaa gagcggguaa uuccauccau ccuggcaauu      480

cagaagaacc ccaauuucaa gcugggcacu gaagugcagg auaaaaucgu cagcgccacc      540

gguuugcucg ccgggaacga gaccgcacca cccgaggugg ugaauaacuu uacgccaauu      600

cugcaagacu guaucaagaa uaucgaucgc uaugcccugg acgaucucaa aaguaaggcg      660

cuguucaacg ucuuggccgc accgacuuac gacauuaccg aauaucugag ggccacuaaa      720

gagaagcccg aaaacacccc augguacggc aagaucgaug gcuucauuaa ugagcucaaa      780

aagcuggcac uguaugggaa aaucaacgac aauaacuccu ggauuaucga caaugguauc      840

uaccacauug cccccuuggg caagcuccau agcaacaaua aaaucgggau ugaaacccug      900

acugagguga ugaagguaua uccauaccug uccaugcagc accuccagag ugccgaucag      960

aucaagcggc auuacgacag caaagaugcg gagggcaaca agauuccccu ggacaaauuu     1020

aagaaagaag guaaggagaa guauugcccg aaaacguaca ccuucgauga cgggaaggug     1080

aucaucaaag caggcgcccg cgucgaagag gaaaagguga aaagguugua uugggccucc     1140

aaggagguga auagccaauu uuuccggguc uacggcauug auaaaccccu ggaggaaggg     1200

aacccagacg auauccucac uauggugauu uauaauaguc ccgaggaaua caagcugaac     1260

uccguacugu augguuacga caccaauaac ggcgggaugu acaucgagcc agaaggcacc     1320

uuuuucacuu augagcgcga ggcacaggaa agcacguaca ccuuggagga acucuuuagg     1380

cacgaguaua cucacuaccu gcagggucgg uaugccgugc ccggccagug ggggaggacc     1440

aagcuguacg auaaugaccg ccucaccugg uaugaggaag gcggggcgga gcuguucgcc     1500

gguaguacuc ggacguccgg cauuuugcca aggaaaagca ucgucagcaa cauucauaac     1560

accacucgca auaaccggua caagcugucc gacaccgugc acaguaaaua cggggcgagc     1620

uuugaguucu auaauuacgc cuguauguuu auggauuaua uguacaacaa ggacaugggc     1680

auccucaaua aacugaacga ucuggcaaag aauaacgacg ucgaugguua ugacaauuac     1740

aucagggauu uguccagcaa cuaugcccug aaugacaagu accaagauca uaugcaggaa     1800

cgcauugaca acuacgaaaa ucucacugug ccguucgugg ccgaugacua ucugguacgg     1860

cacgcauaca aaaaccccaa ugagaucuau agugagauuu ccgaaguggc caagcucaaa     1920

gaugcaaaga gcgaggucaa aaagucccag uacuuuagua ccuucacgcu gaggggcagc     1980

uauaccgggg gcgccuccaa ggggaaauug gaagaccaaa aggcaaugaa caaauucauc     2040

gacgauagcc ugaagaaacu cgacacuuac aguugguccg gcuacaagac ccugacugcc     2100

uauuuuacca acuacaaagu ggauagcucc aaucggguca cguaugacgu gguguuccac     2160

gguuaccugc caaacgaggg ggauaguaag aauagcuugc ccuauggcaa gauuaacggu     2220

accuacaaag gcacugaaaa ggagaaaauc aaguuuucca gcgaggggag uuucgaccca     2280

gauggcaaaa ucguauccua ugaaugggac uuuggggaug gcaauaagag caacgaggaa     2340

aaucccgagc auuccuacga caaggugggu accuacacug ucaaacugaa ggugaccgau     2400

gacaaagggg aaagcagugu cagcacgacc acugccgaga uuaaggaccu cuccgagaac     2460

aaacugccgg ugaucuauau gcacgugcca aagaguggcg cacucaauca gaagguaguc     2520

uucuacggca aagggaccua ugaucccgac gguagcauug cgggcuacca gugggauuuu     2580

ggggacggcu ccgauuucag cuccgaacag aaccccaguc auguguauac uaagaaaggu     2640

gaguacaccg ugacgcugcg cgucauggac agcuccgggc aaaugaguga aaagaccaug     2700

aaaaucaaga uuacugaucc aguguauccc aucggcaccg agaaagagcc aaauaacagc     2760

aaggaaacug ccuccggccc gaucgugccc gggauuccag uaagcgguac caucgagaau     2820

accagugacc aggauuacuu uuacuucgac gucauuacuc ccggcgaagu gaagaucgau     2880

auuaacaaau ugggguaugg cggugcaacg uggguggucu acgacgagaa uaacaacgcc     2940

guguccuaug ccaccgauga cgggcagaau cugagcggca aguuuaaagc agacaagcca     3000

ggcagguacu auauccaccu guacauguuc aacggguccu auaugcccua ccggauuaau     3060

aucgaaggua gcguaggccg cuga                                            3084


<210>  5232
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5232
auagccaaca ccaacucaga aaaauacgac uucgaauacc uaaacggccu aagcuacacc       60

gaacuaacca accucaucaa aaacauaaaa uggaaccaaa uaaacggccu auucaacuac      120

agcaccggca gucaaaaguu cuucggugac aagaaccgcg uccaggcgau aaucaacgcc      180

cuacaagaau ccggccgcac cuacacagcc aacgacauga aaggcauaga aacauucacg      240

gaaguacuac gugcuggauu cuaucuaggc uauuauaacg acggacugag cuaccuaaac      300

gacaggaacu uucaagacaa augcaucccc gccaugauag caauccagaa aaaucccaac      360

uuuaaacucg gaacggcggu ccaagacgag gugaucacgu cacuuggaaa acucauagga      420

aacgcgagcg ccaacgccga gguaguaaau aacugcguac caguccugaa gcaauuccgu      480

gaaaaucuua accaauacgc cccagacuac guaaaaggaa cugcggucaa cgagcucaua      540

aaaggaauag aguucgacuu cagcggagcc gcauaugaaa aagacguaaa gaccaugccc      600

ugguacggca aaauagaccc guucaucaac gaacucaagg cacuaggccu auacggcaac      660

aucacaagcg ccaccgaaug ggccucagac gucgggaucu acuaccuauc aaaauucgga      720

cucuacagca caaaccgaaa cgacaucgua caaucccuag aaaaagcagu cgacauguac      780

aaauacggaa agaucgcauu cgucgccaug gagcgcauca cgugggauua cgacggaaua      840

ggcucaaacg gaaagaaagu cgaccacgac aaauuccucg acgacgcaga aaaacacuac      900

cugccgaaaa cuuauacguu ugacaacggc accuucauua uccgcgcggg cgacaaagua      960

ucugaggaaa agaucaaacg acuauacugg gcuagccgag aaguaaaaag ccaguuccac     1020

cgaguagucg gaaacgauaa ggcgcucgaa guaggaaacg ccgacgacgu ccuuacuaug     1080

aagaucuuca acagccccga agaauacaaa uucaacacua acaucaacgg cguauccaca     1140

gacaacggag gccuauacau cgaaccuagg ggcaccuucu acaccuacga acgcacccca     1200

caacaaucaa ucuucucucu ugaagaacuc uuccggcacg aguacaccca cuaccuacaa     1260

gcacgauacc ucgucgacgg ccuauggggc caaggaccau ucuacgagaa aaacagacuc     1320

accugguuug acgaagggac cgcugaguuc uucgccggca gcacaagaac aucaggaguc     1380

cucccccgaa agagcauccu aggauaccug gccaaggaca agguagauca ccgcuacagc     1440

cuaaagaaga cacuaaacag cggcuacgac gacuccgacu ggauguucua uaauuacggc     1500

uucgcgguag cacacuaccu guaugaaaaa gacaugccaa ccuucaucaa aaugaacaaa     1560

gcaauacuaa acaccgaugu caaaagcuac gaugaaauua ucaaaaagcu gagcgacgac     1620

gcaaauaaaa acaccgaaua ucaaaaccac auccaggaac ucgccgacaa auaccaaggc     1680

gcagggaucc cccugguguc agacgacuac cuaaaagacc acggcuacaa gaaagccucg     1740

gaagucuacu ccgaaaucag uaaagcagcc agccuaacca auacaucagu uacagccgaa     1800

aagagccagu acuucaacac auucacacug aggggcaccu acacaggcga aacuuccaaa     1860

ggggaguuca aggacuggga cgaaaugagc aagaagcucg acggcacccu cgaaucacuc     1920

gcuaaaaauu cauggucggg auacaagacu uuaacggcau acuucacgaa cuaccgagug     1980

acaagcgaca acaaagucca auacgacguc gucuuucacg gcguccugac cgacaacgca     2040

gacauaucca acaacaaagc accgaucgca aaagucaccg gaccgagcac cggggcaguc     2100

gggagaaaca ucgaguucuc aggcaaagac uccaaggacg aggacggcaa aaucgucagc     2160

uacgacuggg acuucggaga cggcgcaaca agccggggca agaacucagu ccacgccuac     2220

aagaaagcag gaaccuacaa cguaacacua aaaguaaccg acgacaaagg ggcaacagcc     2280

accgaaucgu ucaccauaga aaucaaaaac gaagacacca ccacccccau uacgaaagag     2340

auggaaccga augacgacau caaagaggcu aacggcccua ucgucgaggg cguaaccgua     2400

aaaggcgacc uuaacggauc ggaugacgca gacaccuucu acuucgacgu aaaagaagau     2460

ggcgacguca cuaucgagcu cccauacucc ggcuccagca acuucaccug gcucguauac     2520

aaggaaggug acgaccagaa ccacaucgcu ucggggauag acaaaaauaa cucuaaaguu     2580

ggcacauuca agagcacaaa aggccggcau uacguuuuca uauacaagca cgacuccgcu     2640

ucaaacauca guuacagccu caacaucaag ggacugggaa augagaagcu caaagagaaa     2700

gagaacaacg acuccuccga caaagccacg guaauaccca acuucaauac gaccaugcaa     2760

gguucucuac ucggcgacga cagcagggac uacuacucgu uugaggucaa ggaggaaggc     2820

gaaguaaaca uagagcuuga caagaaagac gaguucggug ugacguggac acuacaccca     2880

gaguccaaca uaaaugacag aauaacauac ggccagguag acggcaacaa ggugagcaac     2940

aaagucaaac uccgacccgg uaaauacuac cuauuagucu acaaauacuc cggaagcggg     3000

aacuacgagc uacgcgucaa uaaguga                                         3027


<210>  5233
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5233
augaagaaaa acauccucaa aauccuaaug gauagcuacu caaaggaaag uaaaauccag       60

acgguucgcc gagugacguc cgucucccuu cuagcaguau accucacuau gaacacaagc      120

ucccuagucc uggccaaacc cauugaaaac accaacgaca ccucuauaaa gaacguagaa      180

aaacuccgaa acgccccaaa cgaggaaaac ucaaagaaag uagaggauuc uaaaaacgac      240

aaaguagaac acgucaaaaa cauagaagag gccaaaguag aacaagucgc cccggaaguc      300

aaauccaaaa gcacgcugcg gucggcgucu cgccggcgac ggaaacgcau agcaaacaca      360

aacucggaaa aauacgacuu cgaauaccuc aacggacuca gcuacaccga acugacgaac      420

cucaucaaaa acaucaaaug gaaccaaauc aacggacugu ucaacuacuc cacaggaucc      480

caaaaguucu ucggcgacaa aaaccgagua caggcgauca uaaaugcccu gcaggaaagc      540

ggcagaacuu auaccgcaaa ugacaugaag ggcaucgaaa cguucaccga gguccugaga      600

gcgggcuucu accuaggaua cuacaacgac ggacucagcu accucaacga ccgcaacuuu      660

caggauaaau gcauaccggc aaugaucgca auccagaaaa accccaacuu caaacuugga      720

acagcgguac aagaugaggu caucacaucg cugggaaagc uaauaggaaa cgccuccgca      780

aacgccgaag uagucaacaa cugcgucccu guauuaaaac aauuccguga gaaccucaac      840

caauacgccc ccgacuacgu caaaggcacc gccgucaacg aacugauaaa gggcauagag      900

uucgacuuca guggagcagc auacgaaaaa gacgucaaga ccaugcccug guacggcaaa      960

aucgaucccu ucaucaauga acucaaagcg cuuggccucu acggaaacau aaccucugcc     1020

acagaauggg caagcgacgu cggaauauau uaccuaucca aauucggccu cuacagcaca     1080

aacagaaacg acauaguaca gucacucgaa aaagcugucg acauguacaa auacggaaag     1140

auagcauucg ucgcaaugga acgcauaaca ugggacuacg acggcauagg guccaacggc     1200

aagaaaguag accaugacaa guuccuagac gacgcagaaa aacacuaccu gcccaagacc     1260

uacaccuucg acaacggaac cuucauaauc cgagcaggcg acaaaguaag cgaagagaaa     1320

auaaaacgcc uauacugggc cagucgagaa gucaaaucac aauuccaccg agucguaggc     1380

aacgacaagg cacuagaagu gggaaacgcc gacgaugucc uaacuaugaa aaucuucaac     1440

agcccggaag aauacaaauu caacaccaac aucaacgggg ucucaaccga caacggcggg     1500

cuguacauag agccgcgcgg cacguucuac acguacgagc gcacacccca acaaagcauc     1560

uuuucgcuag aagaacuuuu ccgacacgaa uauacccacu acuuacaggc ucgauaccuc     1620

guagauggcc uauggggcca aggcccauuc uacgaaaaga acagacucac cugguucgac     1680

gaaggaaccg cagaguucuu cgcaggaucg accaggacga gcggcguccu cccaaggaaa     1740

uccauacuug gauaccucgc aaaagauaag guagaccacc gguacucacu uaaaaagacu     1800

cucaacucag gauacgacga cuccgacugg auguucuaca acuacggcuu ugccguggcu     1860

cacuaucugu acgaaaagga caugcccacc uucaucaaga ugaacaaagc cauccucaac     1920

accgacguaa aaagcuacga cgaaauaauc aagaaacucu cagacgacgc gaauaaaaac     1980

acagaauacc aaaaucacau acaagagcuc gccgacaaau accagggcgc ggggauaccg     2040

cucgucucug acgacuaccu caaagaccac ggguacaaga aagccagcga ggucuacagu     2100

gaaaucagca aagccgccuc gcuaaccaac accagcguaa cggcggagaa aagccaguac     2160

uucaacaccu ucacacuaag aggaaccuau accggugaga ccagcaaagg cgaguucaag     2220

gacugggacg aaauguccaa gaaauuagac gggacccuag aaucgcuggc caaaaacucc     2280

uggagugggu auaagacccu uaccgcguac uucacaaacu acagagugac cagcgacaau     2340

aaaguccagu acgaugucgu guuccacggc gugcuaacag acaaugcaga caucucaaac     2400

aacaaagccc caaucgccaa agucacggga cccagcacag gcgccguagg ccgcaacauc     2460

gaauuuucag guaaggauuc aaaagacgaa gacggcaaga ucgucagcua cgacugggac     2520

uucggagacg gcgccaccag cagagggaaa aacucaguac acgcguacaa gaaggccggg     2580

accuacaacg ucacccuaaa aguuacggau gacaaaggcg ccacagccac ggaauccuuc     2640

accauagaaa ucaagaacga ggacacaacu acccccauaa ccaaagagau ggagccaaac     2700

gaugacauaa aagaagcuaa cggcccaauc guggaaggcg uuacugucaa aggggaccua     2760

aacggcucag acgacgccga caccuucuac uuugacguaa aagaagacgg ggacgucaca     2820

auagaacucc cauacuccgg aaguagcaac uucaccuggc uaguguacaa ggaaggggau     2880

gaucaaaacc acauagcauc cggcauagac aagaacaacu caaaaguugg gaccuucaaa     2940

ucgaccaaag gccggcacua cguauucauc uacaaacacg acuccgcaag uaauauauca     3000

uacagccuaa acauaaaggg gcugggaaau gaaaaacuua aggaaaaaga aaacaacgac     3060

aguagcgaca aagcaacagu gauccccaac uucaauacaa ccaugcaagg cucacuccuc     3120

ggagaugacu caagggacua cuacucauuc gaagugaagg aagaaggcga agucaacauc     3180

gaacucgaca agaaggacga guucggcguc accuggaccc uccacccuga aucaaacaua     3240

aacgacagga ucaccuacgg ccaaguagac ggaaacaaag ugucaaacaa gguaaaacuc     3300

agaccgggga aauauuaccu acugguguac aaauauucug gaagcggaaa cuacgaacua     3360

cgagucaaca aauag                                                      3375


<210>  5234
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5234
guccaaaacg aaaguaaaag auauaccgua uccuaucuca aaacuuuaaa cuauuacgac       60

cuaguagacc uccugguaaa gacugaaaua gaaaaccugc cagaccuauu ccaauacagc      120

uccgacgcua aggaguucua cgggaacaaa acccgcaugu ccuucaucau ggacgaaauc      180

gggcgacgcg caccacagua caccgaaaua gaccacaaag ggauucccac ucuagucgag      240

gugguacgag ccggauuuua ccuuggauuc cacaacaaag aacucaacga aauaaauaag      300

cgaucauuca aagagcgggu uaucccaagc auacuggcaa uccaaaagaa uccaaacuuc      360

aaacuuggca cagaagucca ggacaaaaua gucuccgcca ccgggcuccu cgccgggaau      420

gaaaccgcac ccccagaagu cgugaauaac uucaccccca uucuccagga cuguauaaag      480

aacaucgacc gcuacgcacu cgacgaccuu aagucaaaag cgcucuuuaa cguccucgcg      540

gcgccuacau acgacaucac agaauaccuu cgcgcgacca aggaaaagcc agaaaacacc      600

ccaugguacg gaaaaauaga cggguucauc aacgaacuaa agaaacuagc gcuauacggc      660

aaaaucaacg acaacaacag cuggaucauu gacaacggca uauaucacau agcaccccug      720

ggaaaacucc acagcaauaa caagaucggc aucgaaaccc uaaccgaagu aaugaaaguc      780

uacccguacc ucuccaugca gcaucuccag agcgccgacc agauaaaacg acacuacgac      840

ucaaaagacg cagaagguaa uaagauccca cuggacaagu ucaaaaagga gggcaaagaa      900

aaauacugcc cuaaaacaua caccuucgac gacggaaagg uaauaauuaa agccggagca      960

cgaguagaag aagaaaaagu aaaacgccuc uacugggccu caaaggaagu uaauucacag     1020

uucuuccgag uguacgguau agacaaacca cuggaggagg gaaacccaga ugacauacug     1080

acgaugguaa uauacaacuc cccggaagaa uacaaacuaa auucaguacu guacggauac     1140

gacaccaaca augggggaau guacaucgaa ccagaaggca ccuucuucac cuacgagcgc     1200

gaagcccagg agucgacaua uacccuagaa gaacuguuuc gccacgagua cacgcacuac     1260

uuacaagggc gcuacgccgu ccccgggcag uggggccgaa ccaaacugua cgacaacgac     1320

cgccucaccu gguacgaaga agggggagca gaacucuucg caggaucgac ccgcaccagc     1380

ggaauacucc cccgcaagag uauagucagc aacauccaca acaccaccag gaacaacaga     1440

uacaaacuuu cagacaccgu ucacagcaag uacggggccu ccuucgaguu uuacaacuac     1500

gcaugcaugu ucauggauua uauguacaac aaagacaugg gaauacuaaa caaacucaau     1560

gaccucgcca aaaacaacga cgucgacggc uacgacaacu acauccgaga ccucagcagc     1620

aacuacgccc uaaacgacaa auaucaagac cacaugcagg agaggauaga uaacuacgaa     1680

aaucucaccg ugccauucgu agccgacgac uaccucguac gucacgccua caaaaacccc     1740

aacgaaaucu acagcgagau cucggaagua gcaaaacuaa aagaugcuaa aucagaggug     1800

aagaaauccc aauacuucuc gaccuucacu cuccgcggcu ccuacacagg aggagccagc     1860

aaagguaaac uagaggacca aaaagcaaug aacaaauuca ucgacgacuc ccucaagaaa     1920

cucgauaccu acagcuggag cggauacaaa acguuaaccg cauauuucac caauuacaaa     1980

guggacaguu ccaaccgagu aaccuacgau guaguguucc auggcuaccu acccaacgag     2040

ggcgacagca aaaacucacu ccccuacgga aagaucaacg ggacauacaa gggcacggaa     2100

aaagagaaaa ucaaauucag cucagaaggc uccuucgacc ccgacggcaa gauugucucc     2160

uacgaguggg acuucgggga cggcaacaaa ucgaacgagg agaacccaga acacagcuac     2220

gacaaggucg gcacguacac cgucaagcuc aaaguaacag acgacaaggg ggaauccagc     2280

guaagcacga caacagcaga aaucaaggac cuauccgaaa auaaacuacc ggugauauac     2340

augcaugucc cuaaauccgg cgcucugaau cagaaggugg uauucuacgg gaagggcacg     2400

uacgaccccg acggauccau agcaggcuac caaugggacu ucggcgaugg uucggacuuu     2460

ucguccgagc agaacccaag ccacguauac acaaagaaag gggaguauac cgucacacuu     2520

cgagucaugg acagcagugg ccagaugagu gagaaaacaa ugaaaaucaa aaucacagau     2580

cccguuuacc cgaucggcac agaaaaagaa ccaaacaauu ccaaagagac ggcgucaggc     2640

ccaaucgugc ccggaauccc cguuucggga accauagaga acacaagcga ccaagacuac     2700

uucuacuucg acgucaucac cccaggcgag guaaaaauag acauaaacaa acuaggauac     2760

ggaggcgcaa cauggguggu auacgacgaa aacaacaacg cggucagcua ugcaacggac     2820

gacggccaaa accuaucagg aaaguucaag gccgacaagc ccggaaggua cuauauacau     2880

uuguacaugu ucaacggcag cuacaugccc uacagaauca acaucgaagg cagcgucggc     2940

cgcuga                                                                2946


<210>  5235
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt8) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5235
augaaacgca aaugccucag caaacgacuc augcuagcua ucaccauggc cacaauauuc       60

accguaaacu ccacccuacc caucuacgcg gcaguggaca aaaacaacgc caccgccgca      120

cgucgccgcc ggaaacgcgu ccaaaacgaa aguaagcgcu auacggugag cuaccucaaa      180

acucucaacu acuaugaucu aguagaccuc cuagucaaaa cggaaauuga aaaccucccc      240

gaccuauucc aguacucauc agacgcgaaa gaguucuacg gcaacaaaac ccggaugucc      300

uucauaaugg acgaaaucgg aaggcgagca ccccaguaua ccgagaucga ccacaagggc      360

auccccacgc ucguagaagu aguuagagca ggcuucuacc ucggguucca caacaaagaa      420

cuaaaugaga ucaacaaacg cuccuucaaa gaacgcguca uccccucaau acuagcaauc      480

cagaaaaacc ccaauuucaa acuaggcacc gagguacaag auaaaaucgu guccgcaaca      540

ggccuccugg cagguaauga aaccgcgccg ccagaaguag ucaacaacuu cacacccauc      600

cuucaggacu gcaucaaaaa cauagacaga uacgcacucg acgaccucaa aagcaaagca      660

cuauucaacg uccucgcagc acccacauau gacauaacgg aauaccuuag agcaaccaaa      720

gaaaaacccg aaaacacacc cugguauggg aaaauagacg gcuucaucaa cgagcuuaaa      780

aagcuggcac uuuacgggaa aauaaacgac aacaacagcu ggaucauaga caacggcauu      840

uaccacaucg caccccuggg gaaauugcac agcaacaaca aaaucggcau agaaacccuc      900

acggagguca ugaaaguuua cccauaccug ucaaugcaac accuccaauc cgccgaccag      960

aucaaacgac acuacgacag caaagacgcc gaaggcaaca agauaccacu agacaaguuc     1020

aagaaagaag gcaaagaaaa auauugcccu aaaaccuaca cauucgacga cggaaaagua     1080

aucauuaaag ccggcgcccg uguagaagaa gaaaagguca aacgccuaua cugggccagc     1140

aaagaaguaa auagccaauu cuuccgcgua uacgggauag acaaaccgcu agaagaagga     1200

aaccccgacg acauacugac caugguaaua uauaacucac cggaagaaua caaacucaac     1260

agcguacuau acggcuauga caccaauaac ggaggaaugu acaucgagcc agaaggaaca     1320

uucuucacgu acgaacguga agcacaagaa uccacauaca cccucgagga acucuuccgu     1380

cacgaguaca cccacuaccu acaggggcga uacgccguac ccggccaaug gggccgcacc     1440

aaacuguaug acaacgaccg gcucaccugg uacgaagaag ggggcgccga acucuucgcc     1500

gguucgacca ggacuucagg aauacugccc cgcaagagca ucguaagcaa cauccacaau     1560

acaacccgca acaaccgcua caaacuauca gacacagucc acuccaaaua cggagcguca     1620

uuugaguucu acaacuacgc uugcauguuu auggauuaua uguacaacaa agauaugggg     1680

auccugaaua aacuaaacga ccuagcgaaa aacaacgacg uugacggcua cgacaacuac     1740

auacgugacc ucucaucaaa cuacgcccua aacgacaaau accaggacca caugcaagaa     1800

cgcaucgaca auuacgaaaa ccuaacagug ccuuuugucg ccgacgacua ccucguacgg     1860

cacgcuuaca aaaaccccaa cgaaaucuau ucagaaaucu cagaagucgc caaauuaaaa     1920

gacgcuaaau ccgaagucaa gaagucccaa uacuucucca cauuuacccu cagaggcuca     1980

uacaccggag gcgcauccaa aggcaaacug gaggaccaaa aagccaugaa caaauucauc     2040

gaugacaguc uaaagaaacu cgacaccuac uccugguccg gauacaaaac gcuaacagcc     2100

uacuucacaa acuacaaagu agacagcucc aaccgaguca ccuacgacgu cgucuuccau     2160

gguuaccucc ccaacgaagg ugacagcaaa aauucacucc ccuacggcaa aauaaacggc     2220

accuacaaag gcaccgaaaa ggagaaaauc aaauucucau cggaaggcag cuucgaccca     2280

gacgggaaga uaguaucgua ugaaugggac uucggggacg gcaacaaauc caaugaagag     2340

aaccccgaac auuccuauga caaagugggg accuacacag uuaagcuaaa aguaaccgac     2400

gacaaaggcg aaucauccgu aucaaccaca acggccgaga uaaaagaucu aagcgaaaac     2460

aaacuccccg uaauauacau gcacgucccu aaaucgggag cucucaacca aaaagucgua     2520

uucuacggaa aaggaacaua cgacccugac ggcuccauag ccggcuacca augggacuuu     2580

ggcgacggca gcgacuucuc cagugagcaa aaccccucac acgucuacac gaaaaagggc     2640

gaauacaccg ugacacuucg cguaauggac agcagcggcc agauguccga gaaaaccaug     2700

aaaaucaaga uuaccgaccc agucuacccc auaggcaccg aaaaggaacc gaacaauagc     2760

aaggaaacag ccagcggccc aauagucccg gggauccccg ucuccggcac gaucgaaaac     2820

acuuccgacc aggacuacuu cuacuucgac guaauaaccc ccggcgaagu aaaaaucgac     2880

aucaacaaac uaggauacgg aggcgccacc ugggucgucu acgaugaaaa caacaacgcc     2940

guauccuaug ccacagacga uggccagaac uugucaggca aguucaaagc ugacaagccc     3000

ggacgcuacu acauccaccu guacauguuc aauggcuccu acaugccaua ccgaauaaac     3060

aucgaaggau cggucggacg cuga                                            3084


<210>  5236
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5236
aucgcaaaca caaacagcga aaaauacgac uucgaauacc ugaacggacu caguuacacc       60

gaacucacaa accucaucaa gaacaucaag uggaaccaaa uaaacggccu cuucaacuac      120

ucgaccggcu cccaaaaguu cuucggggau aagaaccgcg uccaagccau uaucaacgcc      180

cuccaagaaa gcgggcgcac auacaccgcc aacgacauga agggcauaga aacauuuaca      240

gaagugcuac gcgcgggcuu cuaccucggc uauuacaacg acggacucag cuaccuaaac      300

gaccgaaacu uccaggacaa gugcauaccg gcaaugauag ccauccagaa aaaucccaac      360

uuuaaacucg gaacugccgu gcaagacgaa guaaucaccu cgcucggaaa acuaaucggc      420

aacgccucag ccaaugccga aguagucaau aacugcgucc ccgucuuaaa gcaauuccga      480

gagaacuuga accaauacgc accagacuac gucaagggca ccgccguaaa cgaguuaauc      540

aaagggauag aguucgacuu cucgggagcc gcauaugaaa aagacgucaa aaccaugcca      600

ugguacggca aaaucgaccc cuucauaaac gaacucaaag cccuuggccu auacggcaac      660

auaacaagcg cgacagaaug ggccagcgac guaggcaucu acuaccuauc aaaguucgga      720

cucuacagca ccaaccggaa cgacauaguc caaagccucg aaaaagcagu agacauguac      780

aaauacggca aaauagccuu cgucgcaaug gagcgcauaa caugggauua cgacgggauc      840

ggcaguaaug guaagaaagu agaccaugac aaguuccucg acgacgcaga aaaacacuac      900

cuaccuaaga cauacaccuu cgacaacgga accuucauaa uccgcgcagg cgacaaaguu      960

agugaggaga aaaucaaaag acuauacugg gcaucaagag aagucaaauc acaauuccac     1020

cgcguagucg gcaacgacaa agcccucgaa guggggaacg ccgacgacgu ccuaacaaug     1080

aaaaucuuca acagccccga agaauacaaa uucaauacua auauaaacgg aguaagcaca     1140

gacaacggcg gccuauauau cgaaccccgc gggacuuucu auaccuacga aaggacgccg     1200

caacaaucca uauucucacu agaagaacua uuccgccacg aauacaccca cuaccuccag     1260

gcaagauacc uagucgacgg ccuauggggu cagggcccau ucuacgaaaa gaaccgccua     1320

accugguucg acgagggaac agccgaauuu uucgccggau ccacccgcac aagcggaguc     1380

cugccccgca aaucaauacu cggguaccua gcgaaagaca aaguggacca ccgauacagc     1440

cuaaagaaaa cacucaacuc cggauacgau gacagcgacu ggauguucua caacuacgga     1500

uucgccgucg cacacuaccu auacgagaaa gacaugccca cuuucaucaa aaugaacaaa     1560

gcgauacuca acaccgacgu caaaagcuac gacgagauca ucaagaaacu guccgacgac     1620

gcaaauaaaa acaccgaaua ccagaaccac auucaggaac ucgccgacaa auaccaagga     1680

gccggcaucc cacucgucag cgacgacuac cucaaagacc acggguacaa aaaggcgucc     1740

gaaguauauu cugagaucag caaagccgca ucccugacca acacaucagu cacagcagag     1800

aaaucucagu acuucaacac auucacgcuc cgggggaccu acacaggcga aacuagcaaa     1860

ggggaguuca aggacuggga cgagaugagc aagaaacugg auggcacacu cgagagucuc     1920

gcgaaaaacu ccuggucggg cuacaaaacg cuuacagcau auuucaccaa cuaccgcguc     1980

accucagaca acaaagucca auacgacguc guguuccacg gagugcucac cgacaacgcc     2040

gacaucucca acaacaaggc accuaucgca aaggugaccg gccccucaac aggcgcgguu     2100

ggacggaaca ucgaguucuc cgggaaagac aguaaggacg aggacggcaa aauaguaagc     2160

uacgacuggg acuucggaga cggggcgacc ucccgaggca agaacagcgu ccacgccuac     2220

aagaaagccg gcacauacaa cgugacacuu aaaguuaccg acgacaaagg agccaccgcc     2280

acggaguccu uuaccaucga gaucaaaaac gaagacacca caaccccaau aaccaaagaa     2340

auggaaccua acgacgacau uaaggaggca aacggcccaa uaguagaagg aguuacgguc     2400

aagggugacc ucaacgguuc cgaugacgca gacaccuucu acuucgacgu caaagaagac     2460

ggggauguaa ccaucgaacu acccuacucc ggauccucaa auuucacuug gcuaguauac     2520

aaggagggcg acgaccaaaa ccacauagcc ucggggauag acaaaaacaa cucuaaagua     2580

ggaaccuuua aguccacaaa gggacggcac uacgucuuua ucuacaagca cgacuccgcu     2640

uccaacauau cguacucguu aaacaucaaa ggacuaggaa acgaaaaacu caaagagaaa     2700

gaaaacaacg acucaucgga caaagcgaca guaauaccaa acuucaacac cacgaugcag     2760

ggcucccuau ugggagauga cagccgagac uacuacucgu uugaaguaaa agaggaaggc     2820

gaagucaaca ucgaacuaga uaagaaagac gaguucggag uuacguggac ccuccacccc     2880

gagagcaaca ucaaugaccg aauuaccuau ggccaggucg acgguaacaa aguaucuaau     2940

aaagucaaac uccgcccagg caaauacuac cuccucgucu acaaguacag cgguagcggc     3000

aacuacgaac uacgcgugaa uaaauaa                                         3027


<210>  5237
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5237
augaaaaaga acauucucaa aauccucaug gacagcuaca gcaaagagag caagauccag       60

accgugcguc gaguaaccag cgucagcuua cuagcgguau accuaaccau gaacacaucc      120

agccuagucc uggcaaaacc caucgaaaac accaaugaca cuuccaucaa gaacgucgag      180

aagcuacgaa acgcaccaaa cgaagagaau agcaagaaag uugaagauuc caaaaaugac      240

aaaguagagc acgucaaaaa caucgaagaa gcaaaagucg aacaaguagc cccggaaguc      300

aaauccaaga gcacgcuccg cuccgccagu agacggcgca ggaaacgcau cgcaaacaca      360

aacuccgaga aauacgacuu cgaauacuug aacggauuaa gcuacacgga gcuaaccaac      420

cucaucaaaa auauaaaaug gaaccaaaua aacggccuau ucaacuauag caccgggucc      480

cagaaauucu ucggagauaa gaaccgcgua caagcuauca ucaaugcccu gcaggaaucc      540

ggccgcacau acacggccaa cgacaugaaa gguauagaaa cauucacaga agugcuaagg      600

gccggcuucu accucggcua cuacaacgac gggcuaucau accuaaauga cagaaauuuu      660

caggacaaau gcauaccggc uaugaucgcg auacagaaaa acccgaacuu caagcuaggc      720

acggccguac aagacgaagu caucaccucc uugggaaaac ucauaggcaa cgccuccgcg      780

aacgccgaag ucgucaacaa cuguguaccc guccuaaaac aguuuagaga gaaccuaaac      840

caguacgcuc cggacuacgu caaagggaca gcagugaaug aacugauuaa gggaauagag      900

uucgacuucu caggcgcugc cuacgaaaag gacgugaaaa ccaugcccug guacggcaag      960

aucgacccau ucaucaacga auuaaaagca cucggccuau auggcaacau aaccuccgcc     1020

accgaauggg caucggacgu cggaauauac uaccucagua aauuuggacu guauagcacc     1080

aacagaaacg acaucgucca aagccucgag aaagcagucg acauguacaa auacggcaaa     1140

auagccuucg uggcaaugga aaggaucaca ugggacuacg acggcaucgg guccaacgga     1200

aagaaaguag accacgacaa auuucuugac gacgccgaga aacacuaccu accaaaaacu     1260

uacaccuucg acaacggcac cuucauaauc agagcaggag acaaagucag cgaagagaaa     1320

aucaaacggc uuuacugggc cucacgugaa gugaaaagcc aguuccaccg cgucguggga     1380

aaugacaagg cauuggaagu agggaacgcg gacgacgucc uaacaaugaa aauauucaac     1440

agcccagaag aauacaaauu caacacuaac auaaauggag ucuccaccga caacggcggc     1500

cucuacauag aaccaagggg caccuuuuac acauacgaac gcacaccuca gcaaagcaua     1560

uuuucacuag aagaacucuu ccgucacgaa uacacccacu accuccaggc uagauaccuc     1620

guugacggac uguggggcca gggccccuuu uaugagaaaa accgccucac gugguucgac     1680

gaaggcacag ccgaguucuu cgccggcagc acacgaacca gcggcguacu accacgaaaa     1740

ucgauccucg gcuaccuggc aaaagacaaa gucgaucaua gguacagccu caaaaagaca     1800

cuaaacagcg gauaugacga cucugacugg auguuuuaca acuacggguu cgccgucgca     1860

cacuaccucu acgaaaagga caugcccaca uucaucaaaa ugaacaaggc gauccuaaac     1920

acugacguaa aaagcuacga cgaaauaaua aagaagcuaa gcgacgaugc caacaagaac     1980

acagaguacc aaaaccacau ucaggaacuu gccgacaaau accagggagc cggaaucccg     2040

cucguauccg acgacuaccu aaaagaccac ggauacaaaa aggcauccga agucuacagc     2100

gaaauaagca aggccgcguc acuaacaaac acgucaguca ccgcagagaa aucccaauac     2160

uucaacaccu uuacacugag agggacauac accggcgaaa ccucaaaagg agaguucaaa     2220

gacugggacg aaauguccaa gaaacuagac ggaacacucg aaucgcuagc uaaaaacucc     2280

uggagcggau acaaaacccu cacggcuuau uucaccaacu accgcgucac gagcgacaac     2340

aagguacaau augacguugu cuuccacggc guccucacgg acaacgccga caucucaaac     2400

aauaaggccc ccauagcaaa aguaacagga ccauccaccg gcgcagucgg ccgaaacaua     2460

gaguucucag gcaaagauuc caaagacgaa gacgggaaaa ucguuaguua cgauugggac     2520

uucggcgacg gcgccaccuc gcgagguaag aacuccgugc acgcauacaa aaaggccgga     2580

accuacaacg uuacccuaaa ggugacagac gacaaaggag cgacggcgac agaaucuuuc     2640

acaaucgaaa ucaaaaacga agacacuaca acacccauca cgaaagaaau ggagcccaac     2700

gacgacauca aggaagcaaa cgggccgauc guugaaggag uaaccgucaa aggagaccuc     2760

aacgggagcg acgacgcaga caccuucuac uucgauguca aagaggacgg ggacguaaca     2820

aucgagcucc ccuacucagg aagcagcaac uucacauggc uaguguacaa ggagggcgac     2880

gaccagaacc acauagcguc cggcaucgac aaaaacaacu caaaaguagg caccuucaaa     2940

aguaccaaag gccgccacua cguuuucauc uacaagcacg acuccgccuc caacauaagc     3000

uacucgcuaa acaucaaggg cuuaggcaac gaaaaacuga aagaaaaaga aaacaacgac     3060

ucaucugaca aggccaccgu aauacccaau uucaacacaa ccaugcaggg cucacugcuc     3120

ggagacgacu cacgagauua cuacuccuuu gaaguaaaag aagaaggcga aguaaacauc     3180

gaauuggaua agaaagacga guucggcgug acguggacac uucacccaga aucaaacauc     3240

aacgacagga uaaccuaugg gcaaguagac ggcaacaaag uaucuaacaa ggucaagcuc     3300

cgccccggca aguacuaccu gcucgucuac aaauacagcg gaucuggaaa cuaugaacuc     3360

cgcguaaaca aauaa                                                      3375


<210>  5238
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5238
guacaaaacg agucgaaaag auacaccgua ucauaccuca agacccucaa cuacuacgau       60

cucgucgauc uauuagucaa gacagaaauc gaaaaucuac ccgaccuauu ccaguacuca      120

ucggacgcca aagaguucua cggcaacaaa acacgaauga gcuucauuau ggacgaaaua      180

gguagacgag cgccgcagua cacggaaauc gaccacaaag ggauccccac cuuagucgaa      240

guuguacgcg cgggcuucua ccuaggauuu cacaacaaag aacuuaacga aaucaacaaa      300

cgcaguuuca aagaacgcgu cauccccagc auccuagcga uccagaaaaa ccccaauuuu      360

aaacucggca ccgaaguaca ggacaagaua gugucagcaa caggccugcu cgccggaaac      420

gaaacggccc cacccgaagu agucaauaac uucacaccca uacugcagga cugcaucaaa      480

aauaucgacc gauacgcacu cgacgaccuc aagagcaaag cccucuucaa cgugcucgcc      540

gccccaaccu acgacauaac cgaauacuug agggccacaa aagaaaaacc cgaaaacacc      600

ccaugguacg gcaaaauuga cggauucauc aacgagcuga agaaacucgc ccucuacggg      660

aaaaucaaug acaacaacag cuggaucauc gacaacggca ucuaccacau ugccccgcua      720

ggcaaacuac acuccaacaa caaaaucggc aucgaaacgc ucacggaagu caugaaagua      780

uauccauauc uauccaugca acaccuccaa ucugccgacc aaaucaaacg ccacuacgac      840

agcaaggacg cggaaggaaa caaaauccca cucgacaagu uuaagaagga aggcaaagaa      900

aaauacugcc cuaaaaccua cacguucgau gacgggaaag uaauuaucaa agccggcgcc      960

cgagucgaag aggaaaaggu gaaacgccua uacugggccu ccaaagaggu uaauucacaa     1020

uuuuuccgag ucuauggcau cgacaaacca cucgaggaag guaaccccga cgauauccuc     1080

accaugguaa uauauaauuc gcccgaggaa uauaaacuca acagcgucuu auacggcuac     1140

gacaccaaca acgguggcau guacaucgag ccggaaggca ccuucuucac cuacgagcgu     1200

gaagcccaag aauccacgua cacacuugag gaacuauucc gacaugaaua cacccacuac     1260

cugcaaggcc gguacgcagu accuggccag uggggccgca cuaaacucua cgacaacgac     1320

cgucucaccu gguacgaaga agguggagcc gaacucuucg ccggcuccac ccgcaccagc     1380

ggcauccuac cccgaaaauc cauagucucg aacauucaca acacaacccg aaauaaccgc     1440

uacaaacuca gcgacaccgu acacucaaaa uacggagcca gcuucgaguu cuacaacuac     1500

gcgugcaugu ucauggacua cauguacaac aaagauaugg ggauucuaaa caaacuuaac     1560

gaccucgcca aaaauaacga cgucgacggu uacgacaacu auauacgaga ucuuucaucg     1620

aacuacgcac uaaacgacaa auaccaggac cacaugcaag aacgcaucga caacuacgaa     1680

aaccucaccg uccccuucgu cgcagacgau uaccucgucc gacacgcaua caagaacccc     1740

aacgaaauau acucggagau cagcgaaguc gccaagcuca aagaugcaaa auccgaaguc     1800

aaaaagucac aguacuuuag cacauucaca cuccgcggga gcuacaccgg cggcgcgucc     1860

aagggaaagc ucgaagacca aaaagccaug aacaaauuua uagacgacuc ccucaagaaa     1920

cucgacaccu acucguggag cggcuacaaa acacuuaccg cauacuucac caacuacaaa     1980

guagacagcu caaaucgggu aacuuacgac guagucuucc acggcuaccu ucccaaugaa     2040

ggagacagca agaacucacu cccuuacggc aaaauaaaug gaacguacaa gggcacggaa     2100

aaggagaaaa ucaaauucag cuccgaaggc uccuucgacc ccgacggaaa aauaguauca     2160

uacgaauggg acuucggcga cggcaacaag aguaacgaag aaaaucccga acacucauac     2220

gacaaagucg gcacguacac cgucaaacua aaaguaacag acgacaaagg cgaauccuca     2280

gugaguacga ccaccgcaga aaucaaagac uuaucagaaa acaaacuccc cguaauauac     2340

augcacgucc caaagagcgg ggcacucaac caaaaagucg ucuucuacgg caaaggaacc     2400

uacgacccug acggauccau cgccggcuac cagugggauu ucggcgacgg aagcgacuuc     2460

ucaucggagc aaaacccaag ccacgucuac acgaaaaagg gagaauacac agugacacuc     2520

cgaguaaugg acuccucagg gcagaugucc gagaaaacca ugaaaauaaa gaucaccgac     2580

ccugucuacc ccaucggaac cgaaaaggag ccuaacaauu ccaaagaaac cgccagcgga     2640

ccaauaguac ccgguauccc cgucuccgga accaucgaaa acacgucaga ccaggacuac     2700

uucuacuucg acgucauaac cccgggcgaa guaaaaaucg acaucaacaa acuaggcuac     2760

ggcggagcca caugggucgu auacgacgaa aacaacaacg cgguaucuua cgcaacagac     2820

gacggccaaa accuaagcgg caaguucaaa gcagacaaac ccgggcgcua cuacauccac     2880

cuguacaugu ucaacggaag cuacaugcca uacagaauaa auaucgaagg cuccguagga     2940

cguuaa                                                                2946


<210>  5239
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt9) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5239
augaaacgga aaugucuauc caaacgccug augcuggcca uuacgauggc caccaucuuc       60

accgucaacu cuacccugcc gaucuacgcc gccguagaca agaacaacgc caccgccgcu      120

cgccgccgaa gaaagagggu ccaaaacgaa agcaaaagau acacaguaag cuaccuuaag      180

acacucaacu acuacgaccu cguagaccua cucgucaaga cagaaauuga gaaccucccc      240

gaccuauucc aauacagcag cgacgccaaa gaguucuacg gcaacaaaac ccgaaugucu      300

uucauaaugg augaaauagg acgcagagcg ccccaauaca cggaaaucga ucacaaaggc      360

auacccaccc uaguggaagu cguacgagcu ggcuucuauc uggguuucca caacaaagaa      420

cugaacgaaa uaaacaagcg cagcuucaaa gaacgcguga uccccucaau acuggcuauc      480

cagaaaaauc ccaauuucaa acuagggacc gaaguccaag acaagaucgu guccgcgaca      540

ggacuccucg ccggcaacga aaccgccccg ccggaagucg uuaacaacuu cacgccaaua      600

cuacaagacu gcauuaaaaa caucgaccga uacgcccuag acgaucugaa auccaaggca      660

cuauucaacg uucuggccgc accaacauac gacaucacag aguaccugcg ugccacaaaa      720

gaaaaaccag aaaauacccc cugguacggc aaaaucgacg gauucauuaa ugaguugaaa      780

aagcuagcac ucuacggaaa aaucaacgac aauaacagcu ggaucaucga caacggcauu      840

uaccacauag cgccccucgg caaacugcac uccaacaaca aaaucgguau agagacacuc      900

acagagguga ugaaaguuua cccauaccua agcaugcaac accuucaauc cgccgaccaa      960

aucaaacgcc acuacgacuc caaagacgcg gaaggcaaca aaauaccccu cgacaaauuu     1020

aaaaaggagg gcaaagaaaa auacugccca aagaccuaca ccuucgauga cggcaaagua     1080

auaaucaaag caggagccag agucgaggag gagaagguca aaaggcuaua cugggcaucu     1140

aaggaaguga acagccaauu cuuucgggua uacggaaucg acaagccccu agaagaaggu     1200

aaccccgacg acauccuuac aaugguaaua uacaacagcc cggaagagua caaacucaac     1260

aguguucuau acggauacga uacgaacaac ggaggcaugu acaucgaacc ggagggcacc     1320

uucuucaccu acgagcgaga ggcccaagaa agcacauaca ccuuagaaga acuguuccga     1380

cacgaauaca cccauuaccu ccaaggcaga uacgcugucc ccggccaaug gggacgcacu     1440

aaacuauacg auaacgaccg ccuaacaugg uacgaagagg guggcgccga acucuucgcc     1500

ggcucaacga gaacgagcgg aauccugccg cgcaaaagca ucgucagcaa cauacacaac     1560

acaacgcgaa acaaucguua caaacucucg gacacggucc acucaaaaua cggcgcguca     1620

uucgaguucu acaacuacgc cugcauguuc auggauuaca uguacaauaa ggacaugggc     1680

auccuaaaca aacucaacga ccucgcuaaa aacaacgacg ucgacggcua cgacaacuau     1740

auccgagacc uaagcucgaa cuacgcacuc aaugacaaau accaagacca caugcaagag     1800

cgcaucgaca acuacgaaaa ccuaacagua cccuucguug cggacgacua ucucgucagg     1860

cacgcauaca agaacccaaa cgagauauac agcgaaauca gcgagguagc caaacuuaag     1920

gacgccaaau ccgaagucaa gaaaucgcag uacuucucaa ccuucacgcu acguggcagc     1980

uacaccgggg gagcaagcaa aggaaaacuc gaggaccaaa aagcaaugaa caaguuuauu     2040

gacgacagcc uaaagaaacu agauacauau uccugguccg gcuacaaaac gcuaacggca     2100

uacuucacga acuacaaggu ugacucaagu aaccgcguaa cauacgacgu aguuuuccac     2160

ggauaccuac caaaugaagg cgacuccaaa aacucgcugc cauacggaaa aaucaauggc     2220

acauacaaag ggacagagaa ggagaaaauc aaauucaguu cagaaggauc cuucgaccca     2280

gacggcaaaa ucguuucaua ugaaugggau uucggagacg ggaacaaauc aaacgaagaa     2340

aacccugagc acagcuacga caaagucggc acauauacag uaaagcucaa agucacggac     2400

gacaagggcg agagcagcgu aagcacgacc accgcagaaa ucaaggaccu cuccgaaaau     2460

aaacucccag ucauauacau gcacguacca aaaucgggcg cccucaacca gaaaguagug     2520

uucuacggaa aaggcacaua cgauccggac ggauccauag caggcuacca augggauuuc     2580

ggagauggga gcgacuucuc gagcgaacaa aacccgucac acgucuacac uaaaaagggc     2640

gaguacaccg uaacccuucg gguaauggac uccuccggac aaaugucuga gaaaaccaug     2700

aaaaucaaga uaaccgaccc aguauacccc aucggcaccg aaaaagaacc aaacaacucc     2760

aaagaaacug ccuccggccc caucguaccg ggaaucccag ucuccggcac caucgaaaac     2820

accagcgacc aagauuacuu cuacuucgac guaaucaccc ccggagaagu caaaaucgac     2880

aucaacaaac ugggcuacgg aggagcuacc uggguagucu acgacgaaaa caacaacgcc     2940

gucaguuacg ccaccgacga cgggcaaaac cuguccggua aauuuaaggc cgacaagcca     3000

gggcgauacu acauccaccu guauauguuu aacggauccu auaugcccua ccgaauaaau     3060

aucgaaggaa guguaggccg cuaa                                            3084


<210>  5240
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5240
aucgccaaca ccaacagcga gaaguacgac uucgaguacc ugaacggccu cucuuacacg       60

gagcugacca aucugaucaa gaacaucaag uggaaccaga uuaacggguu auucaacuac      120

agcaccggcu cccagaaguu cuucggggac aaaaaccgcg uccaggcgau uaucaacgcc      180

cugcaggaga gcggucggac cuacaccgcu aacgacauga aggggaucga gaccuucacc      240

gagguucugc gcgccggcuu cuaccucggc uacuacaacg acgggcuguc cuaccugaac      300

gaccggaacu uccaggacaa gugcaucccc gccaugaucg cgauccagaa gaacccgaac      360

uucaagcucg gcaccgccgu gcaggacgag gucaucacga gccuggggaa gcugaucggc      420

aacgccuccg ccaacgcgga gguggugaac aacugcgucc ccgugcucaa gcaauuccgc      480

gaaaaccuga accaguacgc ccccgacuac guaaagggga ccgccgucaa cgagcugauc      540

aagggcaucg aguucgacuu uagcggcgcc gccuacgaga aagacgugaa gaccaugccc      600

ugguacggga agaucgaccc guucaucaac gagcucaagg cgcugggccu guacgggaac      660

aucaccuccg ccacggagug ggccagcgac gugggcaucu acuaccucuc caaguucggc      720

cuguacucga ccaaccggaa ugacaucgua cagucccugg agaaggccgu ggacauguac      780

aaguacggga agaucgccuu cguggcgaug gagcgcauca ccugggacua cgacgguauc      840

gggagcaacg gcaagaaggu cgaccacgac aaauuccucg acgacgccga gaagcacuac      900

cugcccaaga ccuacacguu cgacaacggc accuucauca uccgggccgg ugacaaggug      960

uccgaggaga agaucaagcg ccuguacugg gccagccgag aggucaagag ccaguuccac     1020

cgcguggugg gcaacgacaa ggcccucgag guggggaacg cggacgacgu ccugaccaug     1080

aagaucuuca acuccccuga ggaguacaag uucaacacca acaucaacgg cguguccacg     1140

gauaacgggg gccuguacau cgagccccgg gggaccuucu acaccuauga gcgcaccccg     1200

cagcagucca ucuucagccu cgaggagcug uuucggcacg aguacacgca cuaccugcag     1260

gcccgcuacu uaguggacgg ccuguggggc caggggcccu ucuacgagaa gaaccggcug     1320

accugguucg acgagggcac cgccgaguuc uucgccgguu ccacccgcac gagcggcguc     1380

cucccccgaa aguccauccu gggguaccug gccaaggaca agguggacca ccgcuacagc     1440

cucaagaaga cccugaacuc cggcuacgac gacucggacu ggauguucua caacuacggc     1500

uucgcggucg cccacuaccu guacgagaag gacaugccca ccuucaucaa gaugaacaag     1560

gccauccuca acaccgacgu gaaguccuac gacgagauca ucaagaagcu gagcgacgac     1620

gccaacaaga acacggagua ccagaaccac auccaggagc uggcggacaa auaccagggu     1680

gccggcaucc cucucguguc cgacgacuac cugaaggacc acggguacaa gaaggccagc     1740

gaggucuacu ccgagauuag caaggccgcc ucccugacca acaccagcgu gaccgcggag     1800

aagucccagu acuucaacac guucacccuc cggggcaccu acaccggcga aaccagcaag     1860

ggggaguuca aggacuggga cgagaugagc aagaagcugg acggcacgcu ggaaucccug     1920

gccaagaaca gcugguccgg guacaagacc cucaccgccu auuuuaccaa cuaccgcgug     1980

acgagcgaca acaaggucca guacgacgug guguuccacg gcguccugac cgacaacgcc     2040

gacaucucca acaacaaggc ccccaucgcg aaggugaccg ggcccagcac cggcgccgug     2100

ggccggaaca ucgaguucuc cgggaaggac ucuaaggacg aggacggcaa gauagucucc     2160

uacgacuggg acuucgggga cggcgccacg ucccgcggga agaacuccgu ccacgccuac     2220

aagaaggccg gcaccuacaa cgugacccug aaggucaccg acgacaaagg cgcgacggcc     2280

accgagagcu ucaccaucga gaucaagaac gaggacacca cgacccccau caccaaggag     2340

auggagccga acgacgacau caaggaggcc aacgggccca ucguggaggg cgugaccguc     2400

aagggggacc ucaacggcuc cgacgacgca gacacguucu acuucgaugu gaaggaggac     2460

ggggacguga ccaucgagcu gcccuacagc ggcuccagca acuucaccug gcuggucuac     2520

aaggagggcg acgaccagaa ccacaucgcg uccgggaucg acaagaacaa cagcaaggug     2580

ggcaccuuca agagcacgaa ggggcgccac uacguguuca ucuacaagca cgacuccgcc     2640

agcaacaucu ccuacagccu caacaucaag ggccugggga acgagaagcu gaaggagaag     2700

gagaacaacg acuccagcga caaggccacc gucaucccca acuucaacac caccaugcag     2760

ggcucccucc ugggcgacga cagccgggac uacuacuccu ucgaggugaa ggaggagggg     2820

gaggugaaca ucgagcugga caagaaggac gaguucggcg ucacguggac ccuccacccg     2880

gaauccaaca uaaacgaccg caucaccuac ggccaggugg acgggaacaa gguguccaac     2940

aaggucaagc ugcggcccgg caaguacuac cugcucgugu acaaguacag cggguccgga     3000

aacuacgagc ugcgcgugaa caaguga                                         3027


<210>  5241
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5241
augaagaaga acauccugaa gauccucaug gacagcuacu ccaaggagag caagauccag       60

accguccgcc gggugacguc cgugagccug cuggccgucu accucaccau gaacaccucc      120

agccuggugc uggcgaagcc caucgagaac accaacgaca cguccaucaa gaacguggag      180

aagcuccgca acgccccgaa cgaggagaac agcaagaagg ucgaggacuc caagaacgac      240

aagguggagc acgugaagaa caucgaggag gccaaggucg agcaggucgc ccccgagguc      300

aagagcaagu ccacccugcg gagcgccucc cgccggcgcc ggaagcgcau cgcgaacacc      360

aacagcgaga aguacgacuu cgaguaccug aacggccucu ccuacaccga gcugacgaac      420

cugaucaaga acaucaagug gaaccagauc aacgggcugu ucaacuacag caccggcagc      480

cagaaguucu ucggggacaa gaaccgggug caggccauca ucaacgcccu gcaggagucc      540

ggccgcaccu acaccgccaa cgacaugaag gggaucgaga cguucaccga ggugcugcgg      600

gcgggcuucu accucggcua cuacaacgac gggcugagcu accugaacga ccgcaacuuc      660

caggacaagu gcauccccgc caugaucgcc auccagaaga accccaacuu caagcucggc      720

accgccgugc aggacgaggu gaucaccucc cuggggaagc ugaucggcaa cgccagcgcg      780

aacgccgagg uggugaacaa cugcgucccg gugcucaagc aguuccggga gaaccugaac      840

caguacgccc ccgacuacgu gaaggggacg gccgucaacg agcugaucaa gggcaucgag      900

uucgacuucu ccggcgccgc guacgagaag gacgugaaga ccaugcccug guacgggaag      960

aucgaccccu ucaucaacga gcucaaggcc cugggccugu acgggaacau caccagcgcc     1020

accgaguggg ccuccgacgu gggcaucuac uaccucagca aguucggccu guacuccacg     1080

aaccgcaacg acaucgucca gagccuggag aaggccgugg acauguacaa guacgggaag     1140

aucgcguucg ucgccaugga gcggaucacc ugggacuacg acggcaucgg guccaacggc     1200

aagaaggugg accacgacaa guuccucgac gacgccgaga agcacuaccu gccgaagacc     1260

uacaccuucg acaacgggac guucaucauc cgcgccggcg acaaggugag cgaggagaag     1320

aucaagcggc uguacugggc cucccgcgag gucaagagcc aguuccaccg gguggugggc     1380

aacgacaagg cgcucgaggu cgggaacgcc gacgacgugc ugaccaugaa gaucuucaac     1440

ucccccgagg aguacaaguu caacaccaac aucaacggcg ugagcaccga caacgggggc     1500

cuguacaucg agccccgcgg gacguucuac accuacgagc ggacgcccca gcaguccauc     1560

uucagccucg aggagcuguu ccgccacgag uacacccacu accugcaggc ccgcuaccuc     1620

gucgacggcc uguggggcca ggggccguuc uacgagaaga accggcugac cugguucgac     1680

gagggcaccg ccgaguucuu cgcggggucc acccgcacca gcggcgugcu cccccgcaag     1740

agcauccugg gguaccuggc caaggacaag guggaccacc gguacucccu caagaagacg     1800

cugaacagcg gcuacgacga cuccgacugg auguucuaca acuacggcuu cgccgucgcc     1860

cacuaccugu acgagaagga caugcccacc uucaucaaga ugaacaaggc cauccugaac     1920

accgacguca agagcuacga cgagaucauc aagaagcucu ccgacgacgc gaacaagaac     1980

accgaguacc agaaccacau ccaggagcug gccgacaagu accagggggc cggcaucccc     2040

cuggugagcg acgacuaccu caaggaccac ggguacaaga aggccuccga gguguacagc     2100

gagaucucca aggccgcgag ccugaccaac acguccguga ccgccgagaa gucccaguac     2160

uucaacaccu ucacccugcg gggcacguac accggcgaga ccagcaaggg ggaguucaag     2220

gacugggacg agaugagcaa gaagcucgac ggcacccugg agucccuggc caagaacagc     2280

ugguccgggu acaagacgcu caccgccuac uucaccaacu accgcgugac cagcgacaac     2340

aagguccagu acgacguggu guuccacggc guccugacgg acaacgccga caucagcaac     2400

aacaaggcgc cgaucgccaa ggugaccggg cccuccaccg gcgccguggg ccggaacauc     2460

gaguucagcg ggaaggacuc caaggacgag gacggcaaga ucgucagcua cgacugggac     2520

uucggggacg gcgccaccuc ccgcgggaag aacagcgugc acgcguacaa gaaggccggc     2580

acguacaacg ugacccugaa ggucaccgac gacaagggcg ccaccgccac ggaguccuuc     2640

accaucgaga ucaagaacga ggacaccacc acgcccauca ccaaggagau ggagcccaac     2700

gacgacauca aggaggccaa cgggccgauc guggagggcg ugaccgucaa gggggaccuc     2760

aacggcagcg acgacgcgga caccuucuac uucgacguga aggaggacgg ggacgugacg     2820

aucgagcugc ccuacuccgg cagcuccaac uucaccuggc uggucuacaa ggagggcgac     2880

gaccagaacc acaucgccag cgggaucgac aagaacaacu ccaagguggg caccuucaag     2940

agcaccaagg ggcggcacua cguguucauc uacaagcacg acuccgccag caacaucucc     3000

uacagccuca acaucaaggg ccuggggaac gagaagcuga aggagaagga gaacaacgac     3060

uccagcgaca aggccacggu cauccccaac uucaacacca ccaugcaggg cagccuccug     3120

ggcgacgacu cccgcgacua cuacagcuuc gaggugaagg aggaggggga ggugaacauc     3180

gagcuggaca agaaggacga guucggcguc accuggacgc uccaccccga guccaacauc     3240

aacgaccgga ucaccuacgg ccagguggac gggaacaagg ugagcaacaa ggucaagcug     3300

cgcccgggca aguacuaccu gcucguguac aaguacuccg ggagcggcaa cuacgagcug     3360

cgggugaaca aguga                                                      3375


<210>  5242
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5242
guccagaacg agagcaagcg cuacaccgug uccuaccuga agacgcucaa cuacuacgac       60

cugguggacc ugcucgucaa gaccgagauc gagaaccugc ccgaccuguu ccaguacagc      120

uccgacgcca aggaguucua cggcaacaag acccggauga gcuucaucau ggacgagauc      180

gggcgccggg cgccgcagua caccgagauc gaccacaagg gcauccccac gcucguggag      240

gugguccgcg ccggguucua ccugggcuuc cacaacaagg agcugaacga gaucaacaag      300

cgguccuuca aggagcgcgu gauccccagc auccucgcca uccagaagaa ccccaacuuc      360

aagcugggga ccgaggugca ggacaagauc gucuccgcca ccggccugcu cgccggcaac      420

gagaccgcgc cgcccgaggu ggugaacaac uucacgccca uccugcagga cugcaucaag      480

aacaucgacc gguacgcccu ggacgaccuc aagagcaagg cccuguucaa cguccuggcc      540

gcgcccaccu acgacaucac cgaguaccuc cgcgccacca aggagaagcc ggagaacacg      600

cccugguacg ggaagaucga cggcuucauc aacgagcuga agaagcuggc ccucuacggg      660

aagaucaacg acaacaacuc cuggaucauc gacaacggca ucuaccacau cgcgccccug      720

gggaagcugc acagcaacaa caagaucggc aucgagaccc ucaccgaggu gaugaaggug      780

uaccccuacc uguccaugca gcaccuccag agcgccgacc agaucaagcg gcacuacgac      840

uccaaggacg ccgagggcaa caagaucccg cucgacaagu ucaagaagga ggggaaggag      900

aaguacugcc ccaagaccua cacguucgac gacggcaagg ucaucaucaa ggccggggcc      960

cgcguggagg aggagaaggu gaagcggcug uacugggcca gcaaggaggu caacucccag     1020

uucuuccgcg uguacggcau cgacaagccc cuggaggagg gcaaccccga cgacauccuc     1080

accaugguga ucuacaacag cccggaggag uacaagcuga acagcguccu guacggguac     1140

gacaccaaca acggcgggau guacaucgag cccgagggca ccuucuucac guacgagcgg     1200

gaggcccagg aguccaccua cacccucgag gagcuguucc gccacgagua cacccacuac     1260

cugcaggggc gguacgcggu gcccggccag uggggccgca cgaagcucua cgacaacgac     1320

cggcugaccu gguacgagga gggcggggcc gagcuguucg ccgggagcac ccgcaccucc     1380

ggcauccucc cccgcaagag caucgugucc aacauccaca acacgacccg gaacaaccgg     1440

uacaagcuga gcgacaccgu ccacuccaag uacggggcca gcuucgaguu cuacaacuac     1500

gccugcaugu ucauggacua cauguacaac aaggacaugg gcauccugaa caagcucaac     1560

gaccuggcga agaacaacga cguggacggc uacgacaacu acauccgcga ccuguccagc     1620

aacuacgccc ucaacgacaa guaccaggac cacaugcagg agcgcaucga caacuacgag     1680

aaccugaccg ucccguucgu ggccgacgac uaccuggugc ggcacgccua caagaacccc     1740

aacgagaucu acuccgagau cagcgagguc gccaagcuga aggacgcgaa guccgaggug     1800

aagaaguccc aguacuucag cacguucacc cuccgcggga gcuacaccgg cggggccucc     1860

aagggcaagc uggaggacca gaaggccaug aacaaguuca ucgacgacag ccugaagaag     1920

cucgacaccu acuccuggag cggguacaag acgcugaccg ccuacuucac caacuacaag     1980

guggacagcu ccaaccgggu caccuacgac gugguguucc acggcuaccu gcccaacgag     2040

ggcgacagca agaacucccu ccccuacggg aagaucaacg gcaccuacaa ggggacggag     2100

aaggagaaga ucaaguucag cuccgagggc agcuucgacc cggacggcaa gaucgucucc     2160

uacgaguggg acuucgggga cggcaacaag agcaacgagg agaaccccga gcacuccuac     2220

gacaaggugg ggaccuacac cgugaagcug aaggucaccg acgacaaggg cgagagcucc     2280

gugagcacga ccaccgcgga gaucaaggac cuguccgaga acaagcuccc cgugaucuac     2340

augcacgucc ccaagagcgg ggcccugaac cagaaggugg uguucuacgg caagggcacc     2400

uacgacccgg acggguccau cgccggcuac cagugggacu ucggggacgg cagcgacuuc     2460

uccagcgagc agaaccccag ccacgucuac acgaagaagg gggaguacac cgugacccug     2520

cgcgugaugg acuccagcgg ccagaugucc gagaagacca ugaagaucaa gaucacggac     2580

cccgucuacc cgaucggcac cgagaaggag cccaacaaca gcaaggagac cgccuccggg     2640

cccaucgugc ccggcauccc ggugagcggg accaucgaga acacguccga ccaggacuac     2700

uucuacuucg acgucaucac ccccggcgag gugaagaucg acaucaacaa gcucggguac     2760

ggcggcgcca ccuggguggu cuacgacgag aacaacaacg cggugagcua cgccaccgac     2820

gacgggcaga accuguccgg caaguucaag gccgacaagc ccgggcggua cuacauccac     2880

cuguacaugu ucaacggcag cuacaugccc uaccgcauca acaucgaggg guccgugggc     2940

cgguga                                                                2946


<210>  5243
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5243
augaagcgca agugccugag caagcggcuc augcuggcca ucaccauggc gacgaucuuc       60

accgucaacu ccacccugcc caucuacgcc gccguggaca agaacaacgc caccgccgcg      120

cgccggcgcc ggaagcgcgu gcagaacgag agcaagcggu acacggucuc cuaccucaag      180

acccugaacu acuacgaccu gguggaccuc cuggugaaga ccgagaucga gaaccugccg      240

gaccucuucc aguacagcuc agacgccaag gaguucuacg gcaacaagac ccgcaugagc      300

uucaucaugg acgagaucgg gcggcgcgcg ccccaguaca cggagaucga ccacaagggc      360

auucccaccc uggucgaggu ggugcgggcc ggguucuacc ugggcuucca caacaaggag      420

cucaaugaga ucaacaagcg cuccuucaag gagcgaguca ucccaagcau ccuggccauc      480

cagaagaacc cgaacuucaa gcuggggacc gaggugcagg acaagaucgu guccgccacc      540

ggccuccucg ccggcaacga gacggccccg cccgaggucg ugaauaacuu cacccccauc      600

cugcaggacu gcaucaagaa caucgaccgc uacgcccucg acgaccucaa gagcaaggcg      660

cuguucaacg uccuggcagc cccgacauac gacaucaccg aguaccuccg ggccacuaag      720

gagaagcccg agaacacccc cugguacggg aagaucgacg gcuucaucaa cgagcugaag      780

aaacucgccc uguacgggaa gaucaacgac aacaacuccu ggaucaucga caacggcauc      840

uaccacaucg cgccccuggg gaagcuccac agcaacaaca agaucggcau cgagaccuug      900

accgagguca ugaaggugua cccguaccug uccaugcagc accuccaaag cgccgaccag      960

aucaagcgcc acuacgacuc caaggacgcc gagggcaaca agaucccccu ugacaaguuc     1020

aagaaggagg ggaaggagaa auacugcccc aagacguaca ccuucgacga cggcaaggug     1080

aucaucaagg ccggggcccg ggucgaggag gagaagguga agcgguuaua cugggcguca     1140

aaagagguga acagccaguu cuuccggguc uacggcaucg acaagccccu cgaggagggc     1200

aacccggacg acauccugac cauggugauc uacaacuccc ccgaggagua caagcugaac     1260

agcgugcucu acggguacga cacaaacaac ggcggaaugu acaucgagcc cgagggcacg     1320

uucuucacgu acgagcgcga ggcccaggag uccaccuaca cccuggagga gcuguuccgg     1380

cacgaguaca cgcacuaccu ccaggggaga uacgccgucc ccggccagug gggccgcacc     1440

aagcuguacg acaacgaccg gcugaccugg uacgaggagg gaggggccga gcuguucgcc     1500

gggagcaccc gcacguccgg cauccugccg cgcaagagca ucguuuccaa cauccauaac     1560

accacccgga acaacagaua caagcugagc gacaccgucc acuccaagua cggggcgagc     1620

uucgaguuuu acaacuacgc cuguauguuc auggacuaca uguacaacaa ggauaugggc     1680

auacucaaca agcugaacga ccuggccaag aauaacgacg uggacggcua cgacaacuac     1740

auccgcgacc ugucaagcaa cuacgcccuc aacgacaagu accaggacca caugcaggag     1800

cggaucgaca acuacgagaa ccugacggug cccuucgucg cggacgacua ccuggugcgu     1860

cacgccuaca agaaccccaa cgagaucuac ucugagauca gugagguggc caagcucaag     1920

gacgccaagu cagaggucaa gaagucccag uacuucagca ccuucacccu gcgggggagc     1980

uauaccggcg gggccuccaa gggcaagcug gaggaccaga aggccaugaa caaguucauc     2040

gacgacagcc ucaagaagcu ggacaccuac agcugguccg gguacaagac gcugaccgcg     2100

uacuucacca acuacaaggu ggauagcucc aaccgcguaa ccuacgacgu cguguuccac     2160

ggcuaccucc ccaacgaggg cgacagcaag aacucccugc cguacgggaa gaucaacggc     2220

acguacaagg ggaccgagaa ggagaaaauc aaguucagcu ccgagggcuc cuucgacccc     2280

gacggcaaga ucguguccua cgagugggac uucggggacg gcaacaagag caacgaggag     2340

aaccccgaac acuccuacga caaggucggg accuacaccg ugaagcugaa ggugacggac     2400

gacaagggcg agagcuccgu cucuaccacc accgccgaga ucaaggaccu cuccgagaac     2460

aagcugcccg ugaucuacau gcacgugccc aagucagggg cccugaacca aaaggucgug     2520

uuuuacggca agggcacgua cgaccccgac ggguccauag ccggcuacca gugggacuuc     2580

ggggacggca gcgacuucag cuccgagcag aaccccagcc acguguacac caagaagggg     2640

gaguacaccg ucacccucag ggugauggac uccagcggcc agauguccga gaagacgaug     2700

aagaucaaga ucaccgaucc gguguacccc aucggcaccg agaaggagcc gaacaacagc     2760

aaggagaccg cguccgggcc caucgucccg ggcauccccg ugagcgggac gaucgagaac     2820

accuccgacc aggacuacuu cuacuucgac gugaucaccc ccggcgaggu caagaucgau     2880

aucaacaagc ugggguacgg cggcgccacc uggguggugu acgacgagaa caacaacgcc     2940

gucagcuacg cuacggacga cgggcagaac cuguccggca aguucaaggc cgacaagccc     3000

gggcgguacu acauccaccu cuacauguuc aacggcagcu acaugccgua ccggaucaac     3060

aucgaggggu ccguaggccg auga                                            3084


<210>  5244
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5244
auagcaaaua caaacaguga aaaauacgau uucgaauauc ucaacggauu gucauauaca       60

gaacuuacca accuuauuaa aaauauaaaa uggaaccaaa uaaauggucu auuuaauuac      120

aguacggguu cgcagaaauu cuuuggagau aaaaaccgug uacaggccau aauaaacgca      180

cuacaggaau ccggacgcac cuauacggcu aaugauauga aaggaauaga aacuuuuacu      240

gaaguacuaa gagccggauu uuaucucgga uauuacaaug auggauugag uuaccuaaac      300

gauaggaacu uucaagacaa auguauucca gcaaugauag caauacagaa aaaccccaac      360

uucaaauuag gcacagccgu acaagacgaa guuauaacuu cauuaggaaa auuaaucggu      420

aacgcaagcg caaacgccga aguaguaaau aauuguguac caguacuaaa acaauucaga      480

gaaaaccuca accaauacgc acccgauuac guaaaaggga cagcaguaaa ugaauuaaua      540

aaagguaucg aauuugacuu cuccggagca gcuuaugaaa aagacguuaa aacuaugccc      600

ugguacggaa aaauagaucc uuuuauaaau gaacucaaag cauuaggacu cuaugggaau      660

auaacaucgg cuacugaaug ggccagcgac guaggaauau auuauuuauc aaaauuuggg      720

cuauacucaa cgaacaggaa ugauauagua caaucgcuag aaaaagccgu agacauguau      780

aaauauggua aaauugcauu cgucgcaaug gaaagaauua caugggauua ugacggaaua      840

ggguccaacg gcaagaaagu agaucacgau aaauuuuuag acgacgcuga aaaacauuau      900

uuaccaaaaa cauauacuuu ugacaacggu acauucauca uuagggcagg agauaaaguu      960

uccgaagaga aaauaaaaag auuauacugg gcaagucgag aaguaaaauc acaauuccac     1020

agaguaguag gcaacgauaa agccuuagaa gucgguaaug cugacgaugu auuaaccaug     1080

aaaauauuca acaguccuga agaauacaaa uuuaauacca auauaaaugg aguaaguacc     1140

gauaauggcg gacuauacau agaaccucga ggaaccuucu acacguacga acgaacuccg     1200

caacaaucaa uauuuagucu agaagaacua uuucggcaug aauauacgca cuacuuacaa     1260

gcuagauauc uuguagacgg auuauggggg caaggacccu ucuaugaaaa gaaucgauua     1320

acaugguuug acgaaggaac ugcugaauuu uucgcagguu caacaagaac gucaggagua     1380

cuaccaagga aaaguauacu aggcuaccuu gcaaaagaua aaguugauca ucgauauuca     1440

cuaaagaaaa cacuaaauag ugguuaugac gacucagauu ggauguucua uaacuauggu     1500

uuugcagugg cacauuaucu auaugaaaaa gauaugccaa ccuucauaaa aaugaacaaa     1560

gccauauuaa auacugacgu caaaucauac gacgaaauaa uuaagaaauu aucagacgau     1620

gcaaacaaaa auacagaaua ucaaaaccau auacaagaau uagcagauaa auaucaaggu     1680

gcagguauuc cauuaguauc ggaugauuau uuaaaagauc auggauacaa gaaagccagc     1740

gaaguauacu cugaaauuag caaagcagcg ucacucacga auacaucugu uacugcagaa     1800

aaaucacaau auuuuaauac auuuacacug cguggaaccu auaccggaga aacaucaaaa     1860

ggugaauuua aagacuggga cgaaauguca aagaaacuag auggaacccu cgaaaguuua     1920

gccaaaaauu cauggagugg auauaaaacu cuuacugcau acuucacuaa uuacagagua     1980

acaucagaca acaaaguaca auacgacgua guauuucaug gcgucuugac agauaaugcc     2040

gacauuucaa auaacaaagc cccaauagcu aaagugacag gaccaucaac aggcgcaguc     2100

ggaagaaaua uugaguucuc agggaaagau aguaaagacg aagauggaaa aauaguuagc     2160

uaugacuggg acuucggaga uggagcaaca ucucgaggua aaaacuccgu acacgcauau     2220

aagaaagcug gaaccuauaa cguuacauua aaaguaacug augauaaagg agcaacugca     2280

acagaaaguu uuacuauaga aaucaaaaac gaagauacca caacaccaau aacaaaagaa     2340

auggaaccaa acgacgacau aaaagaagcg aauggaccca uaguagaagg agucacuguu     2400

aaaggagacu uaaaugggag cgacgaugcc gacacuuuuu auuucgacgu uaaagaagau     2460

ggagacguaa cuauagaauu acccuacucu ggaaguagua auuuuaccug gcuaguauac     2520

aaagaaggcg augaucaaaa ccauauagcg ucaggaauag auaaaaauaa uucaaaagug     2580

ggcacuuuca aaagcacaaa aggaagacau uacguauuca uuuauaaaca cgauucagca     2640

ucaaacauau cauacucgcu uaauauaaaa ggacuaggaa acgaaaaacu uaaagaaaaa     2700

gaaaacaaug acucaucaga caaagccaca guaauuccaa auuuuaacac uacuaugcaa     2760

ggaagccuuu uaggagauga uaguagagau uauuauucau ucgaaguaaa agaagaagga     2820

gaaguuaaua ucgaacuaga uaagaaagau gaguucggug uaacguggac auuacacccu     2880

gaauccaaua uuaacgacag aaucaccuau ggacaaguug acggaaauaa agucagcaac     2940

aaaguuaaau uaagacccgg aaaauauuac cuccuaguuu auaaauauag cggaucagga     3000

aacuacgaau uacgaguaaa uaaauga                                         3027


<210>  5245
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5245
augaagaaaa auauauuaaa aauauuaaug gacagcuaua gcaaagaauc aaaaauacaa       60

acaguuagaa gaguaacuag cguuagcuua uuagccguau acuuaacaau gaauacaagu      120

agccuaguau uagcaaaacc gauagaaaau acaaacgaca cgagcaucaa aaacguugaa      180

aaacuaagaa augcccccaa cgaagaaaac aguaagaaag ucgaagacag uaaaaaugau      240

aaaguagaac augugaaaaa cauagaagaa gccaaaguag aacaaguagc cccugaaguu      300

aaaagcaaau caacgcuacg cagcgccagu aggagaagaa gaaaaagaau agcaaauacu      360

aacucagaaa aauaugacuu cgaauacuua aauggacuaa guuacacaga acuuaccaau      420

cuuaucaaaa acauaaaaug gaaucaaaua aauggacuau ucaauuauuc cacuggguca      480

caaaaauuuu ucggagauaa aaauagagug caggcuauaa uuaacgcacu acaagaauca      540

ggaagaaccu acacagcaaa cgauaugaaa gggauagaaa cuuucacuga aguacugcga      600

gcgggauucu auuuggggua cuauaacgac gguuuaucau acuuaaacga cagaaauuuu      660

caagacaaau guauaccagc aaugauagca auacagaaaa auccuaauuu uaaacuaggg      720

accgcaguac aagacgaagu gauaacauca cucgguaaac ucauaggaaa ugcuucagcu      780

aaugcggaag uaguaaauaa uugcguacca guuuuaaaac aauucagaga aaaccucaac      840

caauaugcac ccgacuaugu aaaaggaacu gcaguuaacg aacuuaucaa aggaaucgaa      900

uuugauuuua gcggagccgc guacgaaaaa gacgugaaaa caaugccuug guauggaaaa      960

auagacccau ucauuaacga auuaaaagcc uuaggccugu acgguaauau aacuucagcc     1020

acagaauggg caagugacgu uggcauauac uauuugucga aauuuggauu guauucaaca     1080

aaccguaacg acauaguuca aagccuggaa aaagcaguag auauguacaa auauggaaaa     1140

auagccuuug uagcaaugga aaggauuaca ugggauuaug acggaauagg cucaaauggu     1200

aagaaaguag aucaugauaa guuucuagac gaugcagaaa aacacuaucu uccaaagaca     1260

uacaccuucg acaauggaac uuuuauuaua agggcaggcg acaaaguauc cgaagagaaa     1320

auaaaacguu uauacugggc aucacgggaa guaaaaagcc aauuucauag aguaguagga     1380

aacgacaaag cauuagaagu aggaaacgca gaugacguac ucacaaugaa aauauucaau     1440

ucuccugaag aauauaaauu caauacaaau auaaauggag ucaguacaga caauggagga     1500

cuauacauag aaccuagagg gacauuuuau acuuacgaaa gaacacccca acaauccaua     1560

uuuucccuag aagaauuguu ccgacaugaa uacacacauu auuuacaagc ccgauacuua     1620

guagacggau uauggggaca agguccauuc uacgagaaaa acagauugac augguucgac     1680

gaaggaacag cagaauuuuu cgccggauca acuagaaccu ccgguguauu accaagaaaa     1740

uccauccuug gguacuuagc aaaagauaaa guagaucauc guuauucguu aaagaaaaca     1800

uuaaauagcg gcuacgauga uucagauugg auguuuuaua auuauggcuu ugcuguagca     1860

cauuaucuau acgaaaaaga uaugccaacu uucaucaaaa ugaacaaagc gaucuuaaau     1920

acagacguua aaucauauga cgaaaucaua aagaaauuau cagaugaugc aaauaaaaac     1980

acagaauauc aaaaccacau acaagaacua gcugauaaau aucagggugc aggaauccca     2040

cucguaucgg acgauuaccu aaaagaccau ggauauaaga aagcaagcga aguauacuca     2100

gaaauuagua aagcugcauc ucuuacaaau acaagcguaa cggcagagaa aagccaauau     2160

uucaacacgu ucacacuacg cggaacauau acuggagaaa caaguaaagg agaguucaaa     2220

gauugggacg aaaugucaaa gaaauuagau gguacuuuag aaucauuagc caaaaauagc     2280

ugguccgggu acaaaacacu uaccgcauac uuuacaaauu auagagucac aagcgauaau     2340

aaaguucaau acgaugucgu cuuucacgga guacuaacag acaacgcgga uauaagcaau     2400

aauaaagcac caauagcaaa aguaacagga ccaucaaccg gagcuguugg aagaaacauu     2460

gaguucucag gaaaagacuc aaaagacgaa gauggcaaaa uaguaagcua ugauugggau     2520

uuuggagacg gcgcaacauc cagaggcaaa aauagcgucc augccuauaa gaaagcagga     2580

acauacaacg uaacauuaaa aguaacagac gacaaaggag ccaccgccac ugaaaguuuu     2640

acuaucgaaa ucaaaaauga agauacaacc accccaauaa ccaaagaaau ggaaccuaau     2700

gaugacauaa aagaagcuaa ugggccaauu guagaaggag ucacagucaa aggcgacuua     2760

aacgggagcg acgacgcuga uaccuucuac uuugacguaa aagaagaugg agauguaaca     2820

auagaacuac cauauucagg uucauccaau uuuacauggc uaguguacaa agaaggugac     2880

gaccaaaacc auauagccag uggaauugac aaaaacaauu cuaaaguggg gacuuuuaaa     2940

agcacaaaag guagacauua uguauuuaua uacaaacaug auagugcaag caacauauca     3000

uacucucuaa auaucaaagg cuuaggaaac gaaaagcuaa aggaaaagga aaauaacgau     3060

uccucagaua aagcaacugu gaucccaaau uucaacacua cuaugcaagg cagccuucuc     3120

ggugaugaua gccgagauua cuacuccuuu gaagucaaag aagaagguga agucaacaua     3180

gaauuggaua agaaagauga guucggcguc acauggacac ugcauccaga aucaaacaua     3240

aacgauagaa ucaccuacgg acaagucgac ggaaauaaag uaagcaauaa agucaaauua     3300

agaccaggaa aauacuaccu ucuaguauau aaauacucug gaaguggaaa uuacgaauua     3360

cgaguuaaua aauaa                                                      3375


<210>  5246
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5246
guacaaaacg aaucaaaaag auacacagug aguuacuuaa aaacguuaaa cuacuaugac       60

cuaguagacc uucuaguaaa aaccgaaaua gaaaaucuac cagaccuauu ccaauacucu      120

ucagaugcca aagaauuuua uggaaauaaa accagaauga guuucaucau ggaugaaauc      180

ggaaggagag caccacaaua cacggaaaua gaucacaaag guauacccac uuuaguagaa      240

gucguaagag caggauucua cuuaggauuc cauaacaaag aacucaauga aauuaauaaa      300

agaucuuuca aagaaagggu aauacccagc auacucgcca uacagaaaaa ccccaacuuc      360

aaacuaggaa cagaaguaca agauaaaaua guaucagcaa cugguuuacu cgcuggaaau      420

gaaaccgcac caccagaagu aguaaacaac uucaccccua uucuacaaga cugcauuaaa      480

aauauagaca gauacgcccu agacgacuua aaaucgaagg cccucuuuaa cguacuagcc      540

gccccaacau augauauaac agaauacuua agagcaacca aagaaaaacc agaaaauaca      600

cccugguacg gaaaaauaga cggauuuaua aaugaauuaa agaaauuagc guuauauggg      660

aaaauaaacg acaauaauag uuggauaaua gacaacggaa uauaccacau agcaccauua      720

ggcaaacuac acuccaauaa caaaauaggg auagaaaccu uaacagaagu aaugaaagua      780

uauccauauc uaucaaugca acauuugcaa ucagcagacc aaauaaaacg acauuaugau      840

aguaaagacg cagaaggaaa uaaaauacca cuagauaaau ucaagaaaga aggaaaagaa      900

aaauauuguc caaaaacaua cacauucgau gacggaaaag uaauaauuaa agccggugcc      960

cggguagaag aagaaaaagu aaaacgacug uauugggcuu cuaaagaagu caauucacaa     1020

uucuuuaggg uauacggaau ugauaaaccu cuagaagaag guaacccaga cgacauccua     1080

acaaugguca uauacaauag cccggaagaa uacaaauuaa acucgguauu auacggguau     1140

gacacaaaua acggcggcau guacauugaa cccgaaggaa cguucuucac auaugaaaga     1200

gaagcacaag aaucaacaua cacacucgaa gaacuauuua gacacgaaua uacacauuau     1260

uuacaaggga gauacgccgu acccggacaa uggggucgaa ccaaacuuua cgacaacgac     1320

aggcuaacau gguacgaaga agggggagca gaauuauucg caggaucaac aagaaccuca     1380

ggaauacuac cuagaaaaag uauaguauca aauauacaua auacaaccag gaauaacaga     1440

uauaaauuaa gugacacagu ccauucaaaa uauggagccu ccuuugaguu cuauaacuac     1500

gcauguaugu ucauggauua cauguacaac aaagauaugg gaauccuaaa caaacuaaac     1560

gaccuagcua aaaauaacga uguugacgga uacgauaacu acauaagaga ccucagcuca     1620

aacuaugcac uuaacgacaa auaucaagau cauaugcaag aaagaauaga caacuacgaa     1680

aaucucacag uaccauucgu agcagacgau uauuuaguaa gacacgcaua caagaacccu     1740

aacgaaaucu auuccgaaau uagcgaagua gcgaaacuua aagacgcaaa aagugaagua     1800

aagaaaaguc aauacuucag cacauucaca cuacgaggau ccuacacagg cggcgcaagc     1860

aaaggcaaac uagaagauca aaaagcaaug aacaaauuca uagacgauuc acucaagaaa     1920

uuagauacau auagcuggag uggauacaaa acacuaacug cauauuucac aaacuacaaa     1980

guugacagcu caaauagagu cacauaugau guaguauucc acggauaucu acccaaugaa     2040

ggugacagca aaaacuccuu accauacgga aaaauuaacg ggacauacaa aggaacagaa     2100

aaagagaaaa uaaaauucuc auccgaaggu agcuuugacc ccgauggaaa aauuguauca     2160

uaugaauggg acuucggaga cggaaauaaa ucaaacgaag aaaauccuga acacagcuau     2220

gauaaaguug gcaccuauac cgugaaacua aaagugacag augacaaagg ugaaucaucc     2280

guauccacaa cgacagcaga aauuaaagac uuaagcgaaa acaaacuacc aguaauauac     2340

augcauguac caaaauccgg cgcauuaaau caaaaagucg uauuuuaugg aaaagggacu     2400

uaugaccccg augggucaau cgcaggcuau caaugggacu ucggcgaugg cucagacuuc     2460

ucaucagaac agaacccauc ucauguuuac acaaagaaag gagaauacac aguaacauua     2520

cgagucaugg auucaucagg ucaaauguca gagaaaacaa ugaaaauaaa aauaacagau     2580

ccgguuuacc caauaggaac agaaaaagaa cccaacaauu caaaagaaac agcaaguggc     2640

ccuauaguuc cagguauucc uguaucaggu acaaucgaaa acacaucaga ccaggauuac     2700

uuuuacuucg acgugauuac gccaggagaa guuaaaaucg auauuaauaa auuaggauau     2760

gguggagcca cguggguagu auacgaugaa aauaauaaug caguaucaua ugccacagau     2820

gacggacaaa aucuuucagg gaaauuuaaa gcugauaaac caggaagaua uuauauacac     2880

cuuuacaugu ucaacgguuc auacaugccu uacagaauaa auauagaagg auccguaggu     2940

agauaa                                                                2946


<210>  5247
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt12) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5247
augaaacgaa aaugcuuauc caaaagacua augcuagcaa uaacaauggc aacaaucuuc       60

accguaaauu caacauuacc aaucuacgca gccguagaua aaaacaaugc aacagcagcu      120

cgaaggagaa ggaaaagggu acaaaacgaa agcaaaagau auaccgucag cuaccuuaaa      180

accuuaaauu acuacgacuu aguagaucuc uuaguaaaaa cagaaauaga aaacuuaccc      240

gauuuguuuc aauauucauc cgacgcaaaa gaguucuacg gaaauaaaac aagaaugagc      300

uucauaaugg acgaaauagg ucggagagcu ccccaauaua ccgaaauaga ucauaaagga      360

auaccaaccu uaguagaagu aguaagagcc ggauuuuacc uuggcuucca uaacaaagaa      420

cuaaacgaaa uaaacaaacg auccuucaaa gagcgcguaa uaccaaguau acuggccauc      480

cagaaaaacc caaacuuuaa auuaggaacg gaaguucaag acaaaauagu aagugcaaca      540

gggcuccuag caggaaacga aacagcuccc ccugaaguug uaaauaacuu cacaccaaua      600

cuucaagacu guauuaaaaa cauagacaga uacgcauuag acgaccuuaa aagcaaagcg      660

uuauuuaacg uacuagcugc acccacuuau gacauaacug aauacuuaag agcaacaaaa      720

gaaaaaccag aaaacacacc uugguauggc aaaauagaug gauuuauaaa ugaacuaaag      780

aaacuggcac uauauggcaa aaucaacgau aauaacaguu ggauaauaga caacgguaua      840

uaucauauag caccacuagg uaaauugcau ucaaacaaua aaauugguau agaaacguua      900

acagagguga ugaaaguaua cccauaccua ucuaugcaac auuuacaauc agcggaucaa      960

auuaaaaggc acuaugauuc aaaagaugcg gaagguaaca aaauaccacu agacaaauuc     1020

aagaaagaag gaaaagaaaa auauuguccc aaaacauaca cauuugauga ugguaaagua     1080

auaauaaaag caggggcucg aguagaagaa gaaaaaguua aacgacuaua cugggccuca     1140

aaagaaguca acucucaauu uuuccgcgua uacggaaucg auaaaccauu agaagaaggu     1200

aauccggaug auauauuaac cauggugauc uacaacucac cagaagaaua caaacuaaau     1260

ucaguccuau auggauacga cacuaauaau gguggaaugu acauagaacc agaaggcaca     1320

uucuucacau acgaaagaga ggcucaagaa ucaacauaca cacuagaaga auuauuccga     1380

cacgaauaca cacauuacuu acaaggaaga uacgcgguac ccggacaaug gggaagaaca     1440

aaacuauacg auaaugaucg acuuacaugg uaugaagaag gaggagccga acuauucgca     1500

ggauccacgc gcaccucagg gauucuucca agaaaaucaa uaguaucaaa uauacacaau     1560

acaacacgaa auaacagaua uaaauuauca gacacaguac acuccaaaua uggcgcaagu     1620

uucgaguucu acaauuacgc auguauguuc auggauuaca uguauaacaa agauaugggg     1680

aucuuaaaca aacuaaacga uuuagcgaaa aacaaugacg uagacggcua ugacaacuac     1740

auacgagacu uauccagcaa uuacgcacuu aacgauaaau accaagauca caugcaagaa     1800

agaauagaua acuacgaaaa ucuaacaguc ccauuugucg cagacgacua ccuggugaga     1860

cacgcuuaca aaaauccaaa ugaaauauac ucagaaauaa gcgaaguagc uaaacucaaa     1920

gacgccaaaa gugaaguuaa gaaaagucaa uacuuuucaa cauucacccu ccggggauca     1980

uauaccgggg gagcaucuaa aggaaaauua gaagaccaaa aagccaugaa uaaauuuaua     2040

gaugacuccc uaaagaaacu ggacacuuac uccuggagug gguacaaaac uuuaacagcu     2100

uauuucacca acuauaaagu agacagcagc aaucgaguca cauaugacgu cguguuucau     2160

gguuacuuac caaacgaagg agacagcaaa aacucacuuc ccuaugguaa aauaaacggu     2220

acauacaaag gaacagaaaa agagaaaauu aaauucucuu cugaaggauc auuugaucca     2280

gauggaaaaa ucgugaguua ugaaugggac uuuggagacg gaaacaaauc uaacgaagaa     2340

aacccagaac acaguuauga uaaaguugga accuacacag uaaaacuaaa agugacugac     2400

gauaaaggag aaucaucagu caguacaacu acagccgaaa uaaaagaucu aagcgaaaau     2460

aaacuccccg uaauauauau gcacguccca aaaucaggag ccuuaaauca aaaaguuguc     2520

uuuuacggua aaggaacaua cgaucccgau ggaucaaucg caggauauca augggacuuu     2580

ggagauggua gcgauuucuc cagcgaacaa aaccccucac acguauauac aaagaaagga     2640

gaguauacag uaacauuaag agugauggau agcucgggac aaaugucaga gaaaacaaug     2700

aaaauaaaaa uuacggaucc aguauacccc auaggaacag aaaaagaacc aaacaauucc     2760

aaagaaaccg cuaguggucc aaucguaccc ggcauuccgg ugagcgguac uauagagaac     2820

acaucagacc aagauuacuu uuacuucgac gucauuacac caggcgaagu aaaaauagau     2880

auaaauaaau uagguuacgg aggugcaacu uggguaguau augacgagaa caacaacgcc     2940

gucucauacg caaccgacga cggucaaaau cuaucaggaa aauucaaagc agacaaacca     3000

gguagauacu acauucaccu auacauguuc aauggaaguu acaugccaua cagaauaaac     3060

auagaaggau ccguuggaag auaa                                            3084


<210>  5248
<211>  3027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Clostridium 
       histolyticum__BAA77453.1__ColG(111-1118)

<400>  5248
auagcaaaca caaacucaga aaaauaugac uuugaauauc uaaauggauu aucauauaca       60

gaauuaacaa accugaucaa aaacauaaaa uggaaucaaa uaaacggauu auuuaacuau      120

agcacgggau cacagaaauu uuucggcgau aaaaauagag uacaagcaau uauaaaugcu      180

cuccaagaau cuggcagaac guauacagca aacgauauga aaggaaucga aacuuuuaca      240

gaaguccuga gagcagguuu uuacuuaggu uauuacaacg acgggcuaag cuaucuaaau      300

gauagaaacu uccaagacaa auguauacca gcaaugauug caauacagaa aaaccccaau      360

uuuaaauuag gaacagcagu ucaagacgaa guuauaacau cucuuggcaa acuuauaggg      420

aacgcaagcg caaacgcaga aguaguaaac aacuguguac cgguauuaaa acaauucaga      480

gaaaauuuaa aucaauacgc accagacuau guaaaaggaa cagcaguaaa cgaacuaaua      540

aaaggaauag aauuugauuu cagcggagcc gcauaugaaa aggaugucaa aacuaugccg      600

ugguacggaa aaauagaccc auuuauaaau gaacuuaaag cacuagguuu auacggaaac      660

aucacaagcg caacugaaug ggcaucagau guuggaauuu auuaccuauc uaaauuugga      720

cuauacucaa ccaacaggaa cgauauagug caaucucugg aaaaagcugu agacauguau      780

aaauauggaa aaauagcuuu cgucgcaaug gaaagaauaa cuugggauua ugaugguauu      840

ggaucaaacg gcaaaaaggu agaucacgau aaauucuuag augacgcaga aaagcacuac      900

uuaccaaaaa cguauacauu cgacaacggg acuuuuauaa ucagagcagg cgauaaagua      960

uccgaagaga aaauaaaaag auuauacugg gcuucaaggg aaguaaaauc ucaauuccac     1020

cgaguaguag gaaaugauaa agcauuagaa guggguaacg cugaugaugu auuaacaaug     1080

aaaauauuca acagcccuga agaauacaag uucaauacaa auauaaacgg agucucuacc     1140

gauaacggag gcuuauacau ugaaccaaga ggaacauuuu acacauauga aagaacucca     1200

caacaaagca uauucagccu ugaggaacua uuccgacacg aauauacaca uuacuuacaa     1260

gccagguauc uuguagaugg acuuugggga cagggaccuu ucuaugaaaa gaauagacua     1320

accugguucg acgaaggaac agcagaguuc uuugcagguu caacaagaac aucuggagua     1380

uuaccacgaa aaucaauucu cgguuauuua gcaaaagaua aaguagauca uagauauuca     1440

cuaaagaaaa ccuugaacuc aggauacgac gacagugacu ggauguucua caauuacgga     1500

uuugcaguag cacacuauuu auaugaaaaa gauaugccua cauucauuaa aaugaacaaa     1560

gcaauacuaa auaccgaugu gaaaagcuau gacgaaauaa uaaagaaacu uucagacgau     1620

gcgaacaaaa auacagaaua ccaaaaccau auucaagaac ucgccgacaa auaccaaggu     1680

gcaggcauuc cucuaguaag ugacgacuau uuaaaagacc auggauacaa gaaagcauca     1740

gaagucuauu cagaaaucag caaagccgca uccuuaacua auacaagcgu cacagcagag     1800

aaaucacaau acuuuaauac auucacgcuu cgaggaacuu auacagguga aacgucaaaa     1860

ggagaguuua aagauuggga ugaaauguca aagaaauuag auggaacacu agaaucguua     1920

gcuaaaaacu cauggucugg auauaaaaca cuaaccgcau acuuuacuaa cuacagaguu     1980

accagugaua acaaaguaca auacgaugua guauuucaug gaguacuaac agacaaugca     2040

gacauuagca auaacaaagc accaauagca aaaguuaccg gccccucaac aggggcagua     2100

gguagaaaua uugaguucuc uggaaaagau agcaaagaug aagauggaaa aauaguuuca     2160

uaugauuggg acuuugguga uggagcaacu agcaggggca aaaacucagu ucacgcauac     2220

aagaaagcag gaacauauaa cguaaccuua aaaguaaccg augauaaagg agcaaccgcc     2280

accgaaaguu uuacuauaga aaucaaaaac gaagacacaa cgacaccaau aacaaaagaa     2340

auggaaccaa augacgacau aaaagaagca aacggaccaa uaguagaagg aguaacagua     2400

aaaggagacc uaaauggcuc ggacgaugca gauacauuuu acuuugaugu caaagaggau     2460

ggugacguaa ccauagaacu acccuauagc ggaucaagua auuucacuug gcuaguuuac     2520

aaagaaggag augaccaaaa ccauauugca ucaggaauug auaaaaacaa cucaaaagua     2580

ggcacauuca aaucaacaaa aggacgacau uacguuuuca uauauaaaca cgacagcgcu     2640

ucaaacauau cauauucucu caacauaaaa gguuuaggca augaaaaauu aaaagaaaaa     2700

gaaaauaacg acucaucaga uaaagcaacc guaaucccaa auuucaauac aacgaugcaa     2760

ggaucgcucc ucggagauga cagucgugau uacuacucau uugaaguaaa agaagaagga     2820

gaaguuaaua uagaacuaga uaagaaagac gaguucggag uaacauggac auuacaccca     2880

gagaguaaua ucaacgauag aauuacauau ggccaaguug acggaaauaa aguuaguaau     2940

aaaguaaaac uuaggccagg aaaauauuac cugcucgucu acaaauacuc agguagcggu     3000

aacuaugaac uaagaguaaa caaauaa                                         3027


<210>  5249
<211>  3375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Clostridium 
       histolyticum__BAA77453.1__ColG(1-110)_CS-F_ColG(111-1118)

<400>  5249
augaagaaaa auauacuaaa aauauugaug gacuccuaua guaaagagag caaaauacaa       60

acaguaaggc gaguaaccag cgugaguuua cuugcuguau aucuaacaau gaacacaagu      120

agccuaguuu uagcaaaacc aauagaaaau acgaaugaua ccuccaucaa aaacguagaa      180

aaacuaagaa augcaccaaa cgaagaaaau ucaaagaaag uagaagauag uaaaaacgac      240

aaaguagaac augugaaaaa cauagaagaa gccaaaguag aacaaguagc accagaaguc      300

aaaucuaaau ccacuuuaag aagugcguca aggagaagaa gaaaaagaau agcaaacaca      360

aauagugaaa aauacgauuu cgaauaccua aacggacuau ccuauacuga acuaacaaau      420

cuaauuaaaa acauaaaaug gaaucaaaua aacgguuuau uuaacuauuc cacaggcuca      480

caaaaauuuu ucggagauaa aaaucgcguu caagcaauaa uaaaugcccu acaagaaagc      540

gggagaaccu acaccgcaaa ugauaugaaa ggaauagaaa cauucacaga aguacuuaga      600

gccgguuucu aucuagguua cuauaacgac ggauuaaguu aucuaaauga uaggaacuuc      660

caagauaaau gcauaccagc aaugaucgca auacagaaaa auccaaauuu caaauuggga      720

acagcagucc aagacgaagu gauaacauca cuaggaaaac uaauaggcaa cgcaagugca      780

aacgccgaag uaguaaacaa cuguguucca guacuaaaac aauucagaga aaaccuaaac      840

caauacgcac cugauuaugu uaaagguaca gccgucaacg aacucauaaa agguauagag      900

uucgacuucu caggagcagc guacgaaaaa gauguaaaaa caaugccaug guauggaaaa      960

auugauccau uuauuaauga auuaaaggca uuaggauugu acggaaacau aaccucggcu     1020

acagaauggg caucagaugu aggaauauac uaccuuucaa aauuuggucu auauagcaca     1080

aaccggaacg auauaguaca aucauuagaa aaagccguag acauguauaa auauggaaaa     1140

auagcauuug ucgcaaugga aagaauaacc ugggacuacg acggaauagg gucuaacggg     1200

aagaaaguag accaugauaa auuucucgau gaugccgaaa aacauuaucu accuaaaacu     1260

uacacuuucg acaauggcac auucauaauc agagcuggcg acaaaguauc cgaagagaaa     1320

auaaaaagau uauauugggc aucuagagag guaaaaaguc aguuucacag agucguagga     1380

aaugauaaag cucuugaggu aggaaacgca gaugacgugu uaacaaugaa aauauuuaau     1440

ucaccggaag aauacaaguu caauacaaac auuaauggcg uauccacaga caauggagga     1500

cuauauaucg aaccacgagg aacauucuau acauaugaaa gaaccccaca acagaguauu     1560

uucagucuag aagaauuauu uaggcacgaa uacacccauu auuuacaagc acguuaucua     1620

guagacggac uaugggguca gggacccuuc uacgaaaaga accgcuuaac augguucgau     1680

gaagguacug cggaauuuuu cgcuggauca acacgaacca guggaguacu cccaagaaaa     1740

ucaauuuuag guuaccuugc aaaagauaaa gucgaucaca gauacucacu caaaaagaca     1800

cuaaauucag gauaugauga cucagacugg auguuuuaua auuauggauu cgcagucgca     1860

cacuaccucu acgaaaaaga uaugccaacg uucauuaaga ugaauaaggc aauacuaaau     1920

acagauguaa aaucauacga cgaaaucaua aagaaacuau ccgacgacgc aaauaaaaau     1980

acagaauacc aaaaccauau acaagaacua gcagacaaau aucagggagc aggcauccca     2040

cuuguaagcg acgacuacuu gaaagaccac ggauacaaga aagcauccga agucuacuca     2100

gaaauaucca aagcagccuc auuaacaaau acguccguaa cugcugagaa aagucaauau     2160

uucaacacau ucacacuacg uggaacauac accggcgaaa cgaguaaagg agaguucaaa     2220

gauugggacg aaaugucaaa gaaauuagac gguacacuag aaucauuagc caaaaauuca     2280

uggagcggau acaaaacucu uacggcauac uuuacaaacu auaggguuac aagugauaac     2340

aaaguacaau augacguagu auuucaugga guccucacag acaaugcuga uaucagcaac     2400

aacaaagcuc cuaucgcuaa aguaacuggg cccaguacgg gagcaguagg cagaaacauu     2460

gaguucucag gaaaagacuc aaaagacgaa gauggcaaaa uaguauccua ugauugggac     2520

uuuggagaug gagcaacauc aagaggcaaa aacucagucc acgcauacaa gaaagcagga     2580

acauauaaug uaacacuuaa aguaacagac gauaaaggcg caacagcaac agaaucauuc     2640

acaauagaaa uuaaaaacga agauacaaca acaccaauaa caaaagaaau ggaaccaaac     2700

gaugauauaa aagaggcaaa cgguccaaua guggaaggag uaacaguaaa aggcgacuug     2760

aaugggagcg acgacgccga cacauuuuau uucgacguua aagaggacgg cgacguaaca     2820

auagaauuac cauacagugg aucaagcaac uuuacguggc uaguuuauaa agaaggagac     2880

gaccaaaacc auauagcaag ugguauagac aaaaacaaua guaaaguagg uacauuuaaa     2940

aguaccaaag gcagacauua cguauuuaua uacaaacacg auucagcauc aaacauauca     3000

uauucucuaa auauaaaagg auuagggaau gaaaaacuua aagaaaaaga gaauaaugac     3060

agcagcgaca aagcaacugu cauacccaac uuuaacacaa caaugcaagg uucacuauua     3120

ggagacgaca gucgagauua uuauagcuuc gaaguaaaag aggaaggaga agucaauaua     3180

gaauuagaua agaaagacga auuuggagua acauggacac uucauccuga aaguaauaua     3240

aacgauagaa uaacauacgg acaaguagac ggaaacaaag ucucaaauaa aguaaaacuu     3300

agaccaggga aauauuaucu acuuguauau aaauacagug gaucagguaa cuaugaacua     3360

agagucaaua aauaa                                                      3375


<210>  5250
<211>  2946
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Clostridium 
       histolyticum__BAA34542.1__ColH(41-1021)

<400>  5250
guacaaaaug aaucaaaaag guacacagua uccuaucuaa aaacguuaaa uuauuacgau       60

uuaguagauc uccuagucaa aacugaaaua gaaaacuuac cagaccuauu ccaauauucg      120

uccgaugcaa aagaauuuua uggaaauaaa acccgaaugu cauucaucau ggacgaaauu      180

ggacgaaggg caccgcaaua cacagaaaua gaucacaaag guauuccaac ccucguagaa      240

gucguaagag cuggcuucua ccuaggauuu cauaauaaag aauuaaauga aauaaacaaa      300

aggucauuca aagaaagagu aauacccucc auauuagcaa uacaaaaaaa uccuaacuuu      360

aaacuuggaa cagaaguuca agacaaaauc guuucagcga ccgguuuacu ggcaggcaac      420

gaaacagcac cucccgaagu cguaaacaac uucacaccaa uuuuacaaga uuguauaaaa      480

aauauugauc gauacgcuuu agacgaccuu aaaagcaaag cgcuauucaa cguacucgca      540

gcaccuacau acgauaucac cgaauaccuu cgagcuacaa aagaaaaacc agaaaauacu      600

ccuugguaug gcaaaauaga cggauucaua aacgaauuaa aaaaauuagc uuuauaugga      660

aaaauuaaug auaauaacuc auggauaaua gacaauggaa uauaucacau ugcaccauua      720

ggaaaauuac auucuaauaa uaaaauagga auagaaacau ugacagaagu aaugaaagug      780

uaccccuacc uaagcaugca acauuuacag ucagcugauc aaauuaaacg acacuacgau      840

ucaaaagacg cagaaggcaa uaaaauccca cuugacaaau ucaaaaaaga aggaaaagaa      900

aaauacuguc caaaaacaua uacauuugac gacggaaaag uaauaauaaa agcuggugca      960

agaguagaag aagaaaaagu caaaagacua uauugggcaa gcaaagaagu aaauucacaa     1020

uucuuucgag uauauggaau ugacaaaccc cuagaagagg gaaacccaga cgauauacua     1080

acaaugguga uauacaacuc accagaagaa uauaaacuaa acaguguacu auacggauac     1140

gauacaaaca auggcgggau guacauagaa ccagaaggua cauucuucac guaugaaagg     1200

gaagcacaag aauccaccua cacacucgaa gaacuauuca gacaugaaua cacucauuau     1260

cuacaaggca gauaugccgu accgggacaa uggggaagaa caaaauuaua ugacaacgac     1320

agauuaacau gguaugaaga aggaggagca gaacuauuug cuggcaguac cagaacaagu     1380

gggauccuuc ccagaaaauc aauugugagu aacauacaca acacaacgag aaauaauaga     1440

uauaaacuaa gcgauaccgu acauaguaaa uauggagccu cguucgaauu uuauaauuau     1500

gccuguaugu ucauggauua cauguauaac aaagauaugg guauauuaaa uaaauuaaac     1560

gaccucgcua aaaauaauga uguagacgga uacgacaacu acauaagaga uuuauccagc     1620

aacuaugcau uaaaugacaa auaucaagac cacaugcaag aaagaaucga caacuaugaa     1680

aaucuuacug uaccauucgu agcagacgau uaccuaguua gacacgccua uaaaaauccc     1740

aacgaaauau auagcgaaau aucugaagua gcaaagcuaa aagacgcaaa aagcgaagug     1800

aaaaaaucac aauacuuuuc aacuuucaca uugagaggcu cauacacagg aggugcaagc     1860

aaaggaaaau uagaagauca aaaagcaaug aauaaauuua uagacgacag ucuaaaaaaa     1920

uuagauacau acucaugguc agguuacaaa acacuaacgg cauacuucac aaacuauaaa     1980

guagauuccu caaauagagu aacauacgau gucguuuuuc auggauaucu accuaacgaa     2040

ggagacagca agaauagucu accauaugga aaaauaaaug gaacguacaa aggaacugaa     2100

aaagaaaaaa ucaaauucuc aucagaaggc aguuucgauc ccgacgggaa aauaguauca     2160

uacgaauggg auuuuggaga uggcaacaaa ucaaacgaag aaaacccaga acauucauau     2220

gauaaagucg gaaccuacac aguaaaacua aaaguaaccg augacaaggg agaaucaucg     2280

guuuccacca cgacagcuga aauaaaagac uuaucagaaa acaaauuacc cguaauauac     2340

augcacguac caaaaucagg cgcgcuuaac caaaaagugg uuuucuaugg aaaaggcaca     2400

uacgauccag auggaagcau cgcaggauac cagugggauu ucggagaugg uucagauuuu     2460

aguucugaac aaaauccuag ccauguauac accaaaaaag gugaauacac aguuacacuu     2520

aggguuaugg acuccucagg acaaaugagc gaaaaaacaa ugaaaauaaa aauaaccgac     2580

ccaguauacc caauaggaac cgaaaaggaa ccaaacaauu cuaaagaaac agcaucaggu     2640

ccaauaguac caggaauccc agugucaggg acaauagaaa acacaucaga ccaagacuau     2700

uucuauuucg acguaauaac acccggagaa guaaaaauag acauaaacaa auuaggauac     2760

gguggcgcca cuuggguugu auaugacgaa aacaacaacg caguaucuua ugcaacugac     2820

gacggccaaa acuuaagugg aaaguuuaaa gccgauaaac cuggacgaua cuacauacac     2880

cuauacaugu ucaacggcag uuacaugcca uacagaauaa acauagaagg uagcguuggu     2940

cgauaa                                                                2946


<210>  5251
<211>  3084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt13) from Clostridium 
       histolyticum__BAA34542.1__ColH(1-40)_CS-F_ColH(41-1021)

<400>  5251
augaaaagaa aaugucuauc aaaaagauua auguuagcaa uaacaauggc uacaauauuc       60

acggucaaca guacacuccc aauauacgcu gcagucgaca aaaacaacgc gacugcagca      120

cgcaggcgca gaaaaagagu acagaaugaa ucaaaacgau acaccguguc guaccuaaaa      180

acccuaaauu acuacgaccu cguugaccua uuaguaaaaa cagaaauaga aaauuuacca      240

gaccuuuuuc aauacucaag cgaugccaag gaauuuuacg gaaauaaaac aaggaugagu      300

uucauaaugg augagaucgg ccgccgagca ccacaauaua ccgaaauaga ucauaaagga      360

aucccgacgu ugguugaagu uguuagagca ggauucuauu uggguuuuca caacaaagaa      420

cuaaaugaaa uaaauaaacg cagcuucaaa gaaagaguaa uaccaagcau cuuagcgauu      480

cagaaaaauc cuaauuucaa acuaggaacg gaaguacaag acaaaaucgu cucagcaacg      540

ggauuguuag cgggaaacga aaccgcucca ccagaagucg uaaacaacuu uacccccaua      600

cuacaagacu gcaucaaaaa uauagauaga uacgcauuag augauuuaaa aucuaaagca      660

uuauucaacg uauuggcggc accaacauau gauauaacag aauauuuaag agcgacaaaa      720

gaaaaaccag aaaacacucc augguauggc aaaauugacg gauuuauaaa ugaauuaaag      780

aaauuggccc uauacggaaa aauaaaugac aauaacagcu ggaucauuga caacggaaua      840

uaccacauag cucccuuagg aaaacuacau aguaacaaua aaaucgguau agaaacauua      900

acugaaguaa ugaaaguuua cccauaucua aguaugcaac auuuacaauc agcagaucaa      960

auaaaaaggc acuaugauag caaagacgca gagggaaaca aaauaccacu agacaaauuu     1020

aagaaagagg gaaaagaaaa auacugucca aaaaccuaca cauucgauga cggaaaagua     1080

aucauaaaag caggagcaag aguagaagag gaaaaaguaa aacgauuaua uugggcaucu     1140

aaagaaguua auucucaauu cuucagagua uacggaauag acaaaccacu agaagaaggc     1200

aauccagacg acauauuaac aaugguaauu uacaacaguc cugaagaaua uaaauuaaau     1260

ucaguauuau auggauacga cacaaacaau ggaggaaugu acaucgaacc cgaaggcaca     1320

uucuuuaccu acgaaagaga ggcucaagaa ucuacuuaua cucucgaaga acuuuuuagg     1380

caugaauaua cacacuaucu ccaagguaga uaugccguac caggacaaug ggguagaaca     1440

aaacuauacg auaaugacag acuuacuugg uaugaagaag gaggcgcaga acuauuugcg     1500

ggcagcacac guacuucagg cauccuacca cgaaaaucca uaguuuccaa cauccacaau     1560

acaacaagaa acaaccgaua uaaauuauca gauacugucc acucaaaaua cggugcgucc     1620

uucgaauuuu acaacuacgc auguauguuu auggacuaca uguauaauaa agauaugggu     1680

auacuuaaca aauugaauga cuuagccaaa aauaaugaug uagacggaua cgauaacuac     1740

auaagagacc uaucaucaaa cuaugcauua aaugacaaau aucaagacca uaugcaagaa     1800

agaauugaua acuacgaaaa cuuaacugua ccauucguag cagaugauua cuuaguaaga     1860

caugcauaua aaaauccaaa cgaaaucuac agcgaaauca gcgaaguagc caaacucaaa     1920

gaugccaaau ccgaagugaa gaaaucacaa uacuucucaa cauucacuuu aagagguagu     1980

uacacaggag gugcauccaa aggaaaauua gaagaccaaa aagccaugaa uaaauuuaua     2040

gacgacaguc uaaagaaauu agauaccuac ucauggagug gauacaaaac auuaacagcc     2100

uacuucacaa acuacaaagu agauucaucu aaccgaguca ccuacgacgu aguauuucau     2160

ggcuacuuac caaacgaagg cgauagcaaa aacucacuac cguacggcaa aauuaacggc     2220

acauacaaag gaacagaaaa agagaaaauc aaauucuccu ccgaagguag cuucgaccca     2280

gacgguaaaa ucguaaguua ugaaugggau uucggugacg gcaacaaauc gaacgaagaa     2340

aacccagaac acagcuauga uaaaguaggu acauauacag ucaaacuaaa aguaaccgau     2400

gauaaaggug aaucgucugu cucaacgacc acagccgaaa uaaaagauuu guccgaaaau     2460

aaauuaccag ucaucuauau gcauguccca aaaucaggag cccuaaacca aaaagugguu     2520

uucuauggaa aaggaacaua cgacccugau ggaucaauag caggcuauca augggauuuc     2580

ggugacggcu cagacuuuag cagugaacaa aauccaucgc auguguacac aaagaaagga     2640

gaauacacag uaacacuacg agucauggau ucuuccggac aaaugaguga gaaaacgaug     2700

aaaauuaaaa uaacagaccc aguauaccca auaggaacag aaaaagaacc aaauaacucc     2760

aaagaaaccg caucuggacc aauagucccc ggaauaccag uaagcggcac uaucgaaaau     2820

acaucagacc aagacuauuu uuacuuugac guaauaaccc caggagaagu aaaaauagac     2880

auaaauaaau uaggauacgg cggcgcuaca uggguaguuu acgacgaaaa caacaaugca     2940

guaucauacg caacagauga cggacaaaac uuaaguggaa aauuuaaagc ugacaaacca     3000

ggaagauauu acauacauuu auauauguuc aauggauccu auaugccaua cagaaucaac     3060

auagaaggaa gcguaggaag guaa                                            3084


<210>  5252
<211>  133
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of mouse NADH dehydrogenase (ubiquinone) 1 alpha 
       subcomplex, 1 (Ndufa1)

<400>  5252
ggaagcattt tcctggctga ttaaaagaaa ttactcagct atggtcatct gttcctgtta       60

gaaggctatg cagcatatta tatactatgc gcatgttatg aaatgcataa taaaaaattt      120

taaaaaatct aaa                                                         133


<210>  5253
<211>  133
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of mouse NADH dehydrogenase (ubiquinone) 1 alpha 
       subcomplex, 1 (Ndufa1) mRNA

<400>  5253
ggaagcauuu uccuggcuga uuaaaagaaa uuacucagcu auggucaucu guuccuguua       60

gaaggcuaug cagcauauua uauacuaugc gcauguuaug aaaugcauaa uaaaaaauuu      120

uaaaaaaucu aaa                                                         133


<210>  5254
<211>  57
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of human proteasome subunit beta 3 (PSMB3)

<400>  5254
ccctgttccc agagcccact tttttttctt tttttgaaat aaaatagcct gtctttc          57


<210>  5255
<211>  57
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of human proteasome subunit beta 3 (PSMB3) mRNA

<400>  5255
cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu gucuuuc          57


<210>  5256
<211>  70
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of human ribosomal protein S9 (RPS9)

<400>  5256
gtccacctgt ccctcctggg ctgctggatt gtctcgtttt cctgccaaat aaacaggatc       60

agcgctttac                                                              70


<210>  5257
<211>  70
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  3'-UTR of human ribosomal protein S9 (RPS9) mRNA

<400>  5257
guccaccugu cccuccuggg cugcuggauu gucucguuuu ccugccaaau aaacaggauc       60

agcgcuuuac                                                              70


<210>  5258
<211>  209
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5258

Met Asp Ser Asp Glu Thr Gly Phe Glu His Ser Gly Leu Trp Val Ser 
1               5                   10                  15      


Val Leu Ala Gly Leu Leu Leu Gly Ala Cys Gln Ala His Pro Ile Pro 
            20                  25                  30          


Asp Ser Ser Pro Leu Leu Gln Phe Gly Gly Gln Val Arg Gln Arg Tyr 
        35                  40                  45              


Leu Tyr Thr Asp Asp Ala Gln Gln Thr Glu Ala His Leu Glu Ile Arg 
    50                  55                  60                  


Glu Asp Gly Thr Val Gly Gly Ala Ala Asp Gln Ser Pro Glu Ser Leu 
65                  70                  75                  80  


Leu Gln Leu Lys Ala Leu Lys Pro Gly Val Ile Gln Ile Leu Gly Val 
                85                  90                  95      


Lys Thr Ser Arg Phe Leu Cys Gln Arg Pro Asp Gly Ala Leu Tyr Gly 
            100                 105                 110         


Ser Leu His Phe Asp Pro Glu Ala Cys Ser Phe Arg Glu Arg Leu Leu 
        115                 120                 125             


Glu Asp Gly Tyr Asn Val Tyr Gln Ser Glu Ala His Gly Leu Pro Leu 
    130                 135                 140                 


His Leu Pro Gly Asn Lys Ser Pro His Arg Asp Pro Ala Pro Arg Gly 
145                 150                 155                 160 


Pro Ala Arg Phe Leu Pro Leu Pro Gly Leu Pro Pro Ala Leu Pro Glu 
                165                 170                 175     


Pro Pro Gly Ile Leu Ala Pro Gln Pro Pro Asp Val Gly Ser Ser Asp 
            180                 185                 190         


Pro Leu Ser Met Val Gly Gly Ser Gln Gly Arg Ser Pro Ser Tyr Glu 
        195                 200                 205             


Ser 
    


<210>  5259
<211>  728
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5259

Met Met Trp Gly Thr Lys Leu Leu Pro Val Leu Leu Leu Gln His Val 
1               5                   10                  15      


Leu Leu His Leu Leu Leu Leu His Val Ala Ile Pro Tyr Ala Glu Gly 
            20                  25                  30          


Gln Lys Lys Arg Arg Asn Thr Leu His Glu Phe Lys Lys Ser Ala Lys 
        35                  40                  45              


Thr Thr Leu Thr Lys Glu Asp Pro Leu Leu Lys Ile Lys Thr Lys Lys 
    50                  55                  60                  


Val Asn Ser Ala Asp Glu Cys Ala Asn Arg Cys Ile Arg Asn Arg Gly 
65                  70                  75                  80  


Phe Thr Phe Thr Cys Lys Ala Phe Val Phe Asp Lys Ser Arg Lys Arg 
                85                  90                  95      


Cys Tyr Trp Tyr Pro Phe Asn Ser Met Ser Ser Gly Val Lys Lys Gly 
            100                 105                 110         


Phe Gly His Glu Phe Asp Leu Tyr Glu Asn Lys Asp Tyr Ile Arg Asn 
        115                 120                 125             


Cys Ile Ile Gly Lys Gly Gly Ser Tyr Lys Gly Thr Val Ser Ile Thr 
    130                 135                 140                 


Lys Ser Gly Ile Lys Cys Gln Pro Trp Asn Ser Met Ile Pro His Glu 
145                 150                 155                 160 


His Ser Phe Leu Pro Ser Ser Tyr Arg Gly Lys Asp Leu Gln Glu Asn 
                165                 170                 175     


Tyr Cys Arg Asn Pro Arg Gly Glu Glu Gly Gly Pro Trp Cys Phe Thr 
            180                 185                 190         


Ser Asn Pro Glu Val Arg Tyr Glu Val Cys Asp Ile Pro Gln Cys Ser 
        195                 200                 205             


Glu Val Glu Cys Met Thr Cys Asn Gly Glu Ser Tyr Arg Gly Pro Met 
    210                 215                 220                 


Asp His Thr Glu Ser Gly Lys Thr Cys Gln Arg Trp Asp Gln Gln Thr 
225                 230                 235                 240 


Pro His Arg His Lys Phe Leu Pro Glu Arg Tyr Pro Asp Lys Gly Phe 
                245                 250                 255     


Asp Asp Asn Tyr Cys Arg Asn Pro Asp Gly Lys Pro Arg Pro Trp Cys 
            260                 265                 270         


Tyr Thr Leu Asp Pro Asp Thr Pro Trp Glu Tyr Cys Ala Ile Lys Thr 
        275                 280                 285             


Cys Ala His Ser Ala Val Asn Glu Thr Asp Val Pro Met Glu Thr Thr 
    290                 295                 300                 


Glu Cys Ile Gln Gly Gln Gly Glu Gly Tyr Arg Gly Thr Ser Asn Thr 
305                 310                 315                 320 


Ile Trp Asn Gly Ile Pro Cys Gln Arg Trp Asp Ser Gln Tyr Pro His 
                325                 330                 335     


Lys His Asp Ile Thr Pro Glu Asn Phe Lys Cys Lys Asp Leu Arg Glu 
            340                 345                 350         


Asn Tyr Cys Arg Asn Pro Asp Gly Ala Glu Ser Pro Trp Cys Phe Thr 
        355                 360                 365             


Thr Asp Pro Asn Ile Arg Val Gly Tyr Cys Ser Gln Ile Pro Lys Cys 
    370                 375                 380                 


Asp Val Ser Ser Gly Gln Asp Cys Tyr Arg Gly Asn Gly Lys Asn Tyr 
385                 390                 395                 400 


Met Gly Asn Leu Ser Lys Thr Arg Ser Gly Leu Thr Cys Ser Met Trp 
                405                 410                 415     


Asp Lys Asn Met Glu Asp Leu His Arg His Ile Phe Trp Glu Pro Asp 
            420                 425                 430         


Ala Ser Lys Leu Asn Lys Asn Tyr Cys Arg Asn Pro Asp Asp Asp Ala 
        435                 440                 445             


His Gly Pro Trp Cys Tyr Thr Gly Asn Pro Leu Ile Pro Trp Asp Tyr 
    450                 455                 460                 


Cys Pro Ile Ser Arg Cys Glu Gly Asp Thr Thr Pro Thr Ile Val Asn 
465                 470                 475                 480 


Leu Asp His Pro Val Ile Ser Cys Ala Lys Thr Lys Gln Leu Arg Val 
                485                 490                 495     


Val Asn Gly Ile Pro Thr Gln Thr Thr Val Gly Trp Met Val Ser Leu 
            500                 505                 510         


Lys Tyr Arg Asn Lys His Ile Cys Gly Gly Ser Leu Ile Lys Glu Ser 
        515                 520                 525             


Trp Val Leu Thr Ala Arg Gln Cys Phe Pro Ala Arg Asn Lys Asp Leu 
    530                 535                 540                 


Lys Asp Tyr Glu Ala Trp Leu Gly Ile His Asp Val His Glu Arg Gly 
545                 550                 555                 560 


Glu Glu Lys Arg Lys Gln Ile Leu Asn Ile Ser Gln Leu Val Tyr Gly 
                565                 570                 575     


Pro Glu Gly Ser Asp Leu Val Leu Leu Lys Leu Ala Arg Pro Ala Ile 
            580                 585                 590         


Leu Asp Asn Phe Val Ser Thr Ile Asp Leu Pro Ser Tyr Gly Cys Thr 
        595                 600                 605             


Ile Pro Glu Lys Thr Thr Cys Ser Ile Tyr Gly Trp Gly Tyr Thr Gly 
    610                 615                 620                 


Leu Ile Asn Ala Asp Gly Leu Leu Arg Val Ala His Leu Tyr Ile Met 
625                 630                 635                 640 


Gly Asn Glu Lys Cys Ser Gln His His Gln Gly Lys Val Thr Leu Asn 
                645                 650                 655     


Glu Ser Glu Leu Cys Ala Gly Ala Glu Lys Ile Gly Ser Gly Pro Cys 
            660                 665                 670         


Glu Gly Asp Tyr Gly Gly Pro Leu Ile Cys Glu Gln His Lys Met Arg 
        675                 680                 685             


Met Val Leu Gly Val Ile Val Pro Gly Arg Gly Cys Ala Ile Pro Asn 
    690                 695                 700                 


Arg Pro Gly Ile Phe Val Arg Val Ala Tyr Tyr Ala Lys Trp Ile His 
705                 710                 715                 720 


Lys Val Ile Leu Thr Tyr Lys Leu 
                725             


<210>  5260
<211>  215
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5260

Met Gly Lys Gly Asp Pro Lys Lys Pro Arg Gly Lys Met Ser Ser Tyr 
1               5                   10                  15      


Ala Phe Phe Val Gln Thr Cys Arg Glu Glu His Lys Lys Lys His Pro 
            20                  25                  30          


Asp Ala Ser Val Asn Phe Ser Glu Phe Ser Lys Lys Cys Ser Glu Arg 
        35                  40                  45              


Trp Lys Thr Met Ser Ala Lys Glu Lys Gly Lys Phe Glu Asp Met Ala 
    50                  55                  60                  


Lys Ala Asp Lys Ala Arg Tyr Glu Arg Glu Met Lys Thr Tyr Ile Pro 
65                  70                  75                  80  


Pro Lys Gly Glu Thr Lys Lys Lys Phe Lys Asp Pro Asn Ala Pro Lys 
                85                  90                  95      


Arg Pro Pro Ser Ala Phe Phe Leu Phe Cys Ser Glu Tyr Arg Pro Lys 
            100                 105                 110         


Ile Lys Gly Glu His Pro Gly Leu Ser Ile Gly Asp Val Ala Lys Lys 
        115                 120                 125             


Leu Gly Glu Met Trp Asn Asn Thr Ala Ala Asp Asp Lys Gln Pro Tyr 
    130                 135                 140                 


Glu Lys Lys Ala Ala Lys Leu Lys Glu Lys Tyr Glu Lys Asp Ile Ala 
145                 150                 155                 160 


Ala Tyr Arg Ala Lys Gly Lys Pro Asp Ala Ala Lys Lys Gly Val Val 
                165                 170                 175     


Lys Ala Glu Lys Ser Lys Lys Lys Lys Glu Glu Glu Glu Asp Glu Glu 
            180                 185                 190         


Asp Glu Glu Asp Glu Glu Glu Glu Glu Asp Glu Glu Asp Glu Asp Glu 
        195                 200                 205             


Glu Glu Asp Asp Asp Asp Glu 
    210                 215 


<210>  5261
<211>  214
<212>  PRT
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5261

Met Asn Phe Leu Leu Ser Trp Val His Trp Thr Leu Ala Leu Leu Leu 
1               5                   10                  15      


Tyr Leu His His Ala Lys Trp Ser Gln Ala Ala Pro Thr Thr Glu Gly 
            20                  25                  30          


Glu Gln Lys Ser His Glu Val Ile Lys Phe Met Asp Val Tyr Gln Arg 
        35                  40                  45              


Ser Tyr Cys Arg Pro Ile Glu Thr Leu Val Asp Ile Phe Gln Glu Tyr 
    50                  55                  60                  


Pro Asp Glu Ile Glu Tyr Ile Phe Lys Pro Ser Cys Val Pro Leu Met 
65                  70                  75                  80  


Arg Cys Ala Gly Cys Cys Asn Asp Glu Ala Leu Glu Cys Val Pro Thr 
                85                  90                  95      


Ser Glu Ser Asn Ile Thr Met Gln Ile Met Arg Ile Lys Pro His Gln 
            100                 105                 110         


Ser Gln His Ile Gly Glu Met Ser Phe Leu Gln His Ser Arg Cys Glu 
        115                 120                 125             


Cys Arg Pro Lys Lys Asp Arg Thr Lys Pro Glu Lys Lys Ser Val Arg 
    130                 135                 140                 


Gly Lys Gly Lys Gly Gln Lys Arg Lys Arg Lys Lys Ser Arg Phe Lys 
145                 150                 155                 160 


Ser Trp Ser Val His Cys Glu Pro Cys Ser Glu Arg Arg Lys His Leu 
                165                 170                 175     


Phe Val Gln Asp Pro Gln Thr Cys Lys Cys Ser Cys Lys Asn Thr Asp 
            180                 185                 190         


Ser Arg Cys Lys Ala Arg Gln Leu Glu Leu Asn Glu Arg Thr Cys Arg 
        195                 200                 205             


Cys Asp Lys Pro Arg Arg 
    210                 


<210>  5262
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5262
auggacucgg acgagaccgg guucgagcac ucaggacugu ggguuucugu gcuggcuggu       60

cuucugcugg gagccugcca ggcacacccc aucccugacu ccaguccucu ccugcaauuc      120

gggggccaag uccggcagcg guaccucuac acagaugaug cccagcagac agaagcccac      180

cuggagauca gggaggaugg gacggugggg ggcgcugcug accagagccc cgaaagucuc      240

cugcagcuga aagccuugaa gccgggaguu auucaaaucu ugggagucaa gacauccagg      300

uuccugugcc agcggccaga uggggcccug uauggaucgc uccacuuuga cccugaggcc      360

ugcagcuucc gggagcggcu ucuugaggac ggauacaaug uuuaccaguc cgaagcccac      420

ggccucccgc ugcaccugcc agggaacaag uccccacacc gggacccugc accccgagga      480

ccagcucgcu uccugccacu accaggccug ccccccgcac ucccggagcc acccggaauc      540

cuggcccccc agccccccga ugugggcucc ucggacccuc ugagcauggu gggagguucc      600

cagggccgaa gccccagcua cgaguccuga                                       630


<210>  5263
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5263
auggacucgg acgagaccgg guucgagcac ucaggacugu ggguuucugu gcuggcuggu       60

cuucugcugg gagccugcca ggcacacccc aucccugacu ccaguccucu ccugcaauuc      120

gggggccaag uccggcagcg guaccucuac acagaugaug cccagcagac agaagcccac      180

cuggagauca gggaggaugg gacggugggg ggcgcugcug accagagccc cgaaagucuc      240

cugcagcuga aagccuugaa gccgggaguu auucaaaucu ugggagucaa gacauccagg      300

uuccugugcc agcggccaga uggggcccug uauggaucgc uccacuuuga cccugaggcc      360

ugcagcuucc gggagcggcu ucuugaggac ggauacaaug uuuaccaguc cgaagcccac      420

ggccucccgc ugcaccuccc agggaacaag uccccacacc gggacccugc accccgagga      480

ccagcucgcu uccugccacu accaggccug ccccccgcac ucccggagcc acccggaauc      540

cuggcccccc agccccccga ugugggcucc ucggacccuc ugagcauggu gggagguucc      600

cagggccgaa gccccagcua cgaguccuga                                       630


<210>  5264
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5264
augauguggg ggaccaaacu ucugccgguc cuguugcugc agcauguccu ccugcaccuc       60

cuccugcuuc augucgccau ccccuaugca gaaggacaga agaaaagaag aaauacacuu      120

caugaauuua aaaagucagc aaaaacuacu cuuaccaagg aagacccauu acugaagauu      180

aaaaccaaaa aagugaacuc ugcagaugag ugugccaaca gguguaucag gaacaggggc      240

uuuacguuca cuugcaaggc cuucguuuuu gauaagucaa gaaaacgaug cuacugguau      300

ccuuucaaua guaugucaag uggagugaaa aaaggguuug gccaugaauu ugaccucuau      360

gaaaacaaag acuauauuag aaacugcauc auugguaaag gaggcagcua uaaagggacg      420

guauccauca cuaagagugg caucaaaugc cagccuugga auuccaugau cccccaugaa      480

cacagcuuuu ugccuucgag cuaucgcggu aaagaccuac aggaaaacua cugucgaaau      540

ccucgagggg aagaaggggg acccuggugu uucacaagca auccagaggu acgcuacgaa      600

gucugugaca uuccucagug uucagaaguu gaaugcauga ccugcaaugg ugaaagcuac      660

agagguccca uggaucacac agaaucaggc aagacuuguc agcgcuggga ccagcagaca      720

ccacaccggc acaaguucuu gccagaaaga uaucccgaca agggcuuuga ugauaauuau      780

ugccgcaauc cugauggcaa gccgaggcca uggugcuaca cucuugaccc ugacaccccu      840

ugggaguauu gugcaauuaa aacgugcgcu cacagugcug ugaaugagac ugaugucccu      900

auggaaacaa cugaaugcau ucaaggccaa ggagaagguu acaggggaac cagcaauacc      960

auuuggaaug gaauucccug ucagcguugg gauucgcagu acccucacaa gcaugauauc     1020

acucccgaga acuucaaaug caaggaccuu agagaaaauu auugccgcaa uccagauggg     1080

gcugaaucac caugguguuu uaccacugac ccaaacaucc gaguuggcua cugcucucaa     1140

auucccaagu gugacguguc aaguggacaa gauuguuauc guggcaaugg gaaaaauuac     1200

augggcaacu uauccaaaac aaggucugga cuuacauguu ccauguggga caagaauaug     1260

gaggauuuac accgucauau cuucugggag ccagaugcua gcaaauugaa uaagaauuac     1320

ugccggaauc cugaugauga ugcccaugga ccuuggugcu acacggggaa uccucuuauu     1380

ccuugggauu auugcccuau uucccguugu gaaggagaua cuacaccuac aauugucaau     1440

uuggaccauc cuguaauauc cugugccaaa acaaaacaac ugcggguugu aaauggcauu     1500

ccaacacaaa caacaguagg guggaugguu aguuugaaau acagaaauaa acauaucugu     1560

ggaggaucau ugauaaagga aaguuggguu cuuacugcaa gacaauguuu uccagccaga     1620

aacaaagacu ugaaagacua ugaagcuugg cuuggcaucc acgauguuca ugagagaggc     1680

gaggagaagc gcaagcagau cuuaaacauu ucccagcugg ucuauggucc ugaaggcuca     1740

gacuugguuu uacugaagcu ugcucgaccu gcaauccugg auaacuuugu caguacaauu     1800

gauuuaccua guuaugguug uacaaucccu gaaaagacca cuugcaguau uuacggcugg     1860

ggcuacacug gauugaucaa cgcggauggu uuauuacgag uagcucaucu guauauuaug     1920

gggaaugaga aaugcaguca gcaccaucaa ggcaagguga cuuugaauga gucugaguua     1980

ugugcugggg cugaaaagau uggaucagga ccaugugagg gagauuaugg uggcccacuc     2040

auuugugaac aacacaaaau gagaaugguu cuugguguca uuguuccugg ucguggaugu     2100

gccaucccaa aucguccugg uauuuuuguu cgaguagcau auuaugcaaa auggauacac     2160

aaaguaauuu ugacauacaa guuguaa                                         2187


<210>  5265
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5265
augauguggg ggaccaaacu ucugccgguc cuguugcugc agcauguccu ccugcaccuc       60

cuccugcuuc augucgccau ccccuaugca gaaggacaga agaaaagaag aaauacacuu      120

caugaauuua aaaagucagc aaaaacuacu cuuaccaagg aagacccauu acugaagauu      180

aaaaccaaaa aagugaacuc ugcagaugag ugugccaaca gguguaucag gaacaggggc      240

uuuacguuca cuugcaaggc cuucguuuuu gauaagucaa gaaaacgaug cuacugguau      300

ccuuucaaua guaugucaag uggagugaaa aaaggguuug gccaugaauu ugaccucuau      360

gaaaacaaag acuauauuag aaacugcauc auugguaaag gaggcagcua uaaagggacg      420

guauccauca cuaagagugg caucaaaugc cagccuugga acuccaugau cccccaugaa      480

cacagcuuuu ugccuucgag cuaucgcggu aaagaccuac aggaaaacua cugucgaaau      540

ccucgagggg aagaaggggg acccuggugu uucacaagca auccagaggu acgcuacgaa      600

gucugugaca uuccucagug uucagaaguu gaaugcauga ccugcaaugg ugaaagcuac      660

agagguccca uggaucacac agaaucaggc aagacuuguc agcgcuggga ccagcagaca      720

ccacaccggc acaaguucuu gccagaaaga uaucccgaca agggcuuuga ugauaauuau      780

ugccgcaauc cugauggcaa gccgaggcca uggugcuaca cucuugaccc ugacaccccu      840

ugggaguauu gugcaauuaa aacgugcgcu cacagugcug ugaaugagac ugaugucccu      900

auggaaacaa cugaaugcau ucaaggccaa ggagaagguu acaggggaac cagcaauacc      960

auuuggaaug gaauccccug ucagcguugg gauucgcagu acccucacaa gcaugauauc     1020

acucccgaga acuucaaaug caaggaccuu agagaaaauu auugccgcaa uccagauggg     1080

gcugaaucac caugguguuu uaccacugac ccaaacaucc gaguuggcua cugcucucaa     1140

auucccaagu gugacguguc aaguggacaa gauuguuauc guggcaaugg gaaaaauuac     1200

augggcaacu uauccaaaac aaggucugga cuuacauguu ccauguggga caagaauaug     1260

gaggauuuac accgucauau cuucugggag ccagaugcua gcaaauugaa uaagaauuac     1320

ugccggaauc cugaugauga ugcccaugga ccuuggugcu acacggggaa uccucuuauu     1380

ccuugggauu auugcccuau uucccguugu gaaggagaua cuacaccuac aauugucaau     1440

uuggaccauc cuguaauauc cugugccaaa acaaaacaac ugcggguugu aaauggcauu     1500

ccaacacaaa caacaguagg guggaugguu aguuugaaau acagaaauaa acauaucugu     1560

ggaggaucau ugauaaagga aaguuggguu cuuacugcaa gacaauguuu uccagccaga     1620

aacaaagacu ugaaagacua ugaagcaugg cuuggcaucc acgauguuca ugagagaggc     1680

gaggagaagc gcaagcagau cuuaaacauu ucccagcugg ucuauggucc ugaaggcuca     1740

gacuugguuu uacugaagcu ggcucgaccu gcaauccugg auaacuuugu caguacaauu     1800

gauuuaccua guuaugguug uacaaucccu gaaaagacca cuugcaguau uuacggcugg     1860

ggcuacacug gauugaucaa cgcggauggu uuauuacgag uagcucaucu guauauuaug     1920

gggaaugaga aaugcaguca gcaccaucaa ggcaagguga cuuugaauga gucugaguua     1980

ugugcugggg cugaaaagau uggaucagga ccaugugagg gagauuaugg uggcccacuc     2040

auuugugaac aacacaaaau gagaaugguu cuugguguca uuguuccugg ucguggaugu     2100

gccaucccaa aucguccugg uauuuuuguu cgaguagcau auuaugcaaa auggauacac     2160

aaaguaauuu ugacauacaa guuguaa                                         2187


<210>  5266
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5266
augggcaaag gagauccuaa gaagccgaga ggcaaaaugu caucauaugc auuuuuugug       60

caaacuuguc gggaggagca uaagaagaag cacccagaug cuucagucaa cuucucagag      120

uuuucuaaga agugcucaga gagguggaag accaugucug cuaaagagaa aggaaaauuu      180

gaagauaugg caaaagcgga caaggcccgu uaugaaagag aaaugaaaac cuauaucccu      240

cccaaagggg agacaaaaaa gaaguucaag gaucccaaug cacccaagag gccuccuucg      300

gccuucuucc ucuucugcuc ugaguaucgc ccaaaaauca aaggagaaca uccuggccug      360

uccauuggug auguugcgaa gaaacuggga gagaugugga auaacacugc ugcagaugac      420

aagcagccuu augaaaagaa ggcugcgaag cugaaggaaa aauacgaaaa ggauauugcu      480

gcauaucgag cuaaaggaaa gccugaugca gcaaaaaagg gaguugucaa ggcugaaaaa      540

agcaagaaaa agaaggaaga ggaggaagau gaggaagaug aagaggauga ggaggaggag      600

gaagaugaag aagaugaaga ugaagaagaa gaugaugaug augaauaa                   648


<210>  5267
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (wt) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5267
augaacuuuc ugcucucuug ggugcacugg acccuggcuu uacugcugua ccuccaccau       60

gccaaguggu cccaggcugc acccacgaca gaaggagagc agaaguccca ugaagugauc      120

aaguucaugg augucuacca gcgaagcuac ugccguccga uugagacccu gguggacauc      180

uuccaggagu accccgacga gauagaguac aucuucaagc cguccugugu gccgcugaug      240

cgcugugcag gcugcuguaa cgaugaagcc cuggagugcg ugcccacguc agagagcaac      300

aucaccaugc agaucaugcg gaucaaaccu caccaaagcc agcacauagg agagaugagc      360

uuccuacagc acagcagaug ugaaugcaga ccaaagaaag acagaacaaa gccagaaaaa      420

aaaucaguuc gaggaaaggg aaagggucaa aaacgaaagc gcaagaaauc ccgguuuaaa      480

uccuggagcg uucacuguga gccuuguuca gagcggagaa agcauuuguu uguccaagau      540

ccgcagacgu guaaauguuc cugcaaaaac acagacucgc guugcaaggc gaggcagcuu      600

gaguuaaacg aacguacuug cagaugugac aagccaaggc gguga                      645


<210>  5268
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt1) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5268
auggacagcg acgagaccgg cuucgagcac uccgggcugu gggugagcgu ccucgccggc       60

cugcugcucg gggccugcca ggcccacccc aucccggacu ccagcccccu gcugcaguuc      120

ggcggccagg ugcgccagcg guaccucuac accgacgacg cccagcagac ggaggcccac      180

cuggagaucc gcgaggacgg gaccgugggc ggggccgccg accagucccc cgagagccug      240

cuccagcuga aggcgcugaa gcccggcguc auccagaucc ucggggugaa gaccucccgg      300

uuccugugcc agcgcccgga cggcgcccug uacgggagcc uccacuucga ccccgaggcc      360

ugcuccuucc gggagcgccu gcucgaggac ggcuacaacg uguaccagag cgaggcccac      420

ggccugcccc ugcaccuccc cgggaacaag uccccgcacc gcgaccccgc gccccggggc      480

cccgcccgcu uccugccgcu gcccgggcuc ccgcccgccc ugcccgagcc gcccggcauc      540

cuggcgcccc agccgcccga cgucggcagc uccgaccccc ucagcauggu ggggggcucc      600

cagggccgga gccccuccua cgagagcuga                                       630


<210>  5269
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt1) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5269
augauguggg gcaccaagcu gcuccccgug cugcugcucc agcacguccu gcugcaccuc       60

cugcugcucc acguggccau cccguacgcc gaggggcaga agaagcgccg gaacacccug      120

cacgaguuca agaagagcgc gaagacgacc cugaccaagg aggacccccu ccugaagauc      180

aagaccaaga aggugaacuc cgccgacgag ugcgccaacc gcugcauccg gaaccgcggc      240

uucacguuca ccugcaaggc cuucgucuuc gacaagagcc ggaagcgcug cuacugguac      300

cccuucaacu ccaugagcuc cggggugaag aagggcuucg ggcacgaguu cgaccuguac      360

gagaacaagg acuacauccg gaacugcauc aucggcaagg gcgggagcua caagggcacc      420

guguccauca ccaagagcgg gaucaagugc cagcccugga acuccaugau cccgcacgag      480

cacagcuucc uccccuccag cuaccgcggc aaggaccugc aggagaacua cugccggaac      540

ccccgcgggg aggagggcgg ccccuggugc uucacgucca acccggaggu ccgguacgag      600

gugugcgaca ucccccagug cagcgaggug gagugcauga ccugcaacgg ggaguccuac      660

cgcggcccca uggaccacac cgagagcggg aagaccugcc agcgguggga ccagcagacg      720

ccccaccgcc acaaguuccu gccggagcgg uaccccgaca agggcuucga cgacaacuac      780

ugccgcaacc ccgacggcaa gccccggccg uggugcuaca cccucgaccc cgacaccccc      840

ugggaguacu gcgccaucaa gaccugcgcg cacuccgccg ucaacgagac ggacgugccc      900

auggagacca ccgagugcau ccaggggcag ggcgaggggu accgcggcac cagcaacacg      960

aucuggaacg ggaucccgug ccagcggugg gacucccagu acccccacaa gcacgacauc     1020

acccccgaga acuucaagug caaggaccug cgcgagaacu acugccggaa ccccgacggc     1080

gccgagagcc cguggugcuu caccaccgac cccaacaucc gcgugggcua cugcagccag     1140

auccccaagu gcgacgucuc cagcgggcag gacugcuacc gcggcaacgg gaagaacuac     1200

augggcaacc uguccaagac gcggagcggg cucaccugcu ccauguggga caagaacaug     1260

gaggaccugc accgccacau cuucugggag cccgacgcca gcaagcugaa caagaacuac     1320

ugccggaacc cggacgacga cgcgcacggc cccuggugcu acaccggcaa cccccucauc     1380

ccgugggacu acugccccau cucccgcugc gagggggaca ccacgcccac caucgugaac     1440

cuggaccacc ccgugaucag cugcgccaag accaagcagc ugcgggucgu gaacggcauc     1500

ccgacccaga cgaccguggg guggaugguc ucccucaagu accgcaacaa gcacaucugc     1560

ggcgggagcc ugaucaagga guccugggug cugaccgccc ggcagugcuu ccccgcccgc     1620

aacaaggacc ucaaggacua cgaggccugg cugggcaucc acgacgugca cgagcggggc     1680

gaggagaagc gcaagcagau ccugaacauc agccagcucg ucuacgggcc cgagggcucc     1740

gaccuggugc ugcucaagcu ggcgcggccc gccauccugg acaacuucgu gagcaccauc     1800

gaccucccgu ccuacgggug cacgaucccc gagaagacca ccugcagcau cuacggcugg     1860

ggcuacaccg ggcugaucaa cgccgacggc cugcuccgcg ucgcccaccu guacaucaug     1920

gggaacgaga agugcuccca gcaccaccag ggcaagguga cccugaacga gagcgagcuc     1980

ugcgccgggg cggagaagau cggcuccggc cccugcgagg gggacuacgg cgggccccug     2040

aucugcgagc agcacaagau gcggaugguc cugggcguga ucgugccggg gcgcggcugc     2100

gccaucccca accggcccgg caucuucguc cgcguggccu acuacgccaa guggauccac     2160

aaggugaucc ugacguacaa gcucuga                                         2187


<210>  5270
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt1) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5270
augggcaagg gggaccccaa gaagccgcgc ggcaagauga gcagcuacgc cuucuucgug       60

cagaccugcc gggaggagca caagaagaag caccccgacg ccagcgucaa cuucuccgag      120

uucagcaaga agugcuccga gcgcuggaag accaugagcg cgaaggagaa ggggaaguuc      180

gaggacaugg ccaaggccga caaggcccgg uacgagcgcg agaugaagac guacaucccg      240

cccaagggcg agaccaagaa gaaguucaag gaccccaacg cccccaagcg gccgcccucc      300

gcguucuucc uguucugcag cgaguaccgc cccaagauca agggggagca ccccggccuc      360

uccaucggcg acguggccaa gaagcugggg gagaugugga acaacaccgc cgccgacgac      420

aagcagcccu acgagaagaa ggcggccaag cugaaggaga aguacgagaa ggacaucgcc      480

gccuaccggg ccaagggcaa gcccgacgcg gccaagaagg ggguggucaa ggccgagaag      540

uccaagaaga agaaggagga ggaggaggac gaggaggacg aggaggacga ggaggaggag      600

gaggacgagg aggacgagga cgaggaggag gacgacgacg acgaguga                   648


<210>  5271
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt1) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5271
augaacuucc ugcucagcug ggugcacugg acccuggccc ugcuccugua ccugcaccac       60

gcgaaguggu cgcaggccgc cccgacgacc gagggcgagc agaagagcca cgaggucauc      120

aaguucaugg acguguacca gcggagcuac ugccgcccca ucgagacccu cguggacauc      180

uuccaggagu acccggacga gaucgaguac aucuucaagc cgucgugcgu cccccugaug      240

cggugcgcgg ggugcugcaa cgacgaggcc cuggagugcg ugccgacgag cgagagcaac      300

aucaccaugc agaucaugcg gaucaagccg caccagucgc agcacaucgg cgagaugagc      360

uuccuccagc acagccgcug cgagugccgg cccaagaagg accggaccaa gccggagaag      420

aagucggugc gcggcaaggg gaagggccag aagcggaagc ggaagaagag ccgcuucaag      480

agcuggucgg uccacugcga gccgugcagc gagcggcgga agcaccuguu cgugcaggac      540

ccccagacgu gcaagugcag cugcaagaac accgacucgc gcugcaaggc ccggcagcug      600

gagcucaacg agcggaccug ccgcugcgac aagccgcggc gguga                      645


<210>  5272
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt2) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5272
auggacuccg acgagaccgg cuucgagcac uccggccucu gggucuccgu ccucgccggc       60

cuccuccucg gcgccugcca ggcccacccc auccccgacu ccuccccccu ccuccaguuc      120

ggcggccagg uccgccagcg cuaccucuac accgacgacg cccagcagac cgaggcccac      180

cucgagaucc gcgaggacgg caccgucggc ggcgccgccg accagucccc cgagucccuc      240

cuccagcuca aggcccucaa gcccggcguc auccagaucc ucggcgucaa gaccucccgc      300

uuccucugcc agcgccccga cggcgcccuc uacggcuccc uccacuucga ccccgaggcc      360

ugcuccuucc gcgagcgccu ccucgaggac ggcuacaacg ucuaccaguc cgaggcccac      420

ggccuccccc uccaccuccc cggcaacaag uccccccacc gcgaccccgc cccccgcggc      480

cccgcccgcu uccucccccu ccccggccuc ccccccgccc uccccgagcc ccccggcauc      540

cucgcccccc agccccccga cgucggcucc uccgaccccc ucuccauggu cggcggcucc      600

cagggccgcu cccccuccua cgaguccuga                                       630


<210>  5273
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt2) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5273
augauguggg gcaccaagcu ccuccccguc cuccuccucc agcacguccu ccuccaccuc       60

cuccuccucc acgucgccau ccccuacgcc gagggccaga agaagcgccg caacacccuc      120

cacgaguuca agaaguccgc caagaccacc cucaccaagg aggacccccu ccucaagauc      180

aagaccaaga aggucaacuc cgccgacgag ugcgccaacc gcugcauccg caaccgcggc      240

uucaccuuca ccugcaaggc cuucgucuuc gacaaguccc gcaagcgcug cuacugguac      300

cccuucaacu ccauguccuc cggcgucaag aagggcuucg gccacgaguu cgaccucuac      360

gagaacaagg acuacauccg caacugcauc aucggcaagg gcggcuccua caagggcacc      420

gucuccauca ccaaguccgg caucaagugc cagcccugga acuccaugau cccccacgag      480

cacuccuucc uccccuccuc cuaccgcggc aaggaccucc aggagaacua cugccgcaac      540

ccccgcggcg aggagggcgg ccccuggugc uucaccucca accccgaggu ccgcuacgag      600

gucugcgaca ucccccagug cuccgagguc gagugcauga ccugcaacgg cgaguccuac      660

cgcggcccca uggaccacac cgaguccggc aagaccugcc agcgcuggga ccagcagacc      720

ccccaccgcc acaaguuccu ccccgagcgc uaccccgaca agggcuucga cgacaacuac      780

ugccgcaacc ccgacggcaa gccccgcccc uggugcuaca cccucgaccc cgacaccccc      840

ugggaguacu gcgccaucaa gaccugcgcc cacuccgccg ucaacgagac cgacgucccc      900

auggagacca ccgagugcau ccagggccag ggcgagggcu accgcggcac cuccaacacc      960

aucuggaacg gcauccccug ccagcgcugg gacucccagu acccccacaa gcacgacauc     1020

acccccgaga acuucaagug caaggaccuc cgcgagaacu acugccgcaa ccccgacggc     1080

gccgaguccc ccuggugcuu caccaccgac cccaacaucc gcgucggcua cugcucccag     1140

auccccaagu gcgacgucuc cuccggccag gacugcuacc gcggcaacgg caagaacuac     1200

augggcaacc ucuccaagac ccgcuccggc cucaccugcu ccauguggga caagaacaug     1260

gaggaccucc accgccacau cuucugggag cccgacgccu ccaagcucaa caagaacuac     1320

ugccgcaacc ccgacgacga cgcccacggc cccuggugcu acaccggcaa cccccucauc     1380

cccugggacu acugccccau cucccgcugc gagggcgaca ccacccccac caucgucaac     1440

cucgaccacc ccgucaucuc cugcgccaag accaagcagc uccgcgucgu caacggcauc     1500

cccacccaga ccaccgucgg cuggaugguc ucccucaagu accgcaacaa gcacaucugc     1560

ggcggcuccc ucaucaagga guccuggguc cucaccgccc gccagugcuu ccccgcccgc     1620

aacaaggacc ucaaggacua cgaggccugg cucggcaucc acgacgucca cgagcgcggc     1680

gaggagaagc gcaagcagau ccucaacauc ucccagcucg ucuacggccc cgagggcucc     1740

gaccucgucc uccucaagcu cgcccgcccc gccauccucg acaacuucgu cuccaccauc     1800

gaccuccccu ccuacggcug caccaucccc gagaagacca ccugcuccau cuacggcugg     1860

ggcuacaccg gccucaucaa cgccgacggc cuccuccgcg ucgcccaccu cuacaucaug     1920

ggcaacgaga agugcuccca gcaccaccag ggcaagguca cccucaacga guccgagcuc     1980

ugcgccggcg ccgagaagau cggcuccggc cccugcgagg gcgacuacgg cggcccccuc     2040

aucugcgagc agcacaagau gcgcaugguc cucggcguca ucguccccgg ccgcggcugc     2100

gccaucccca accgccccgg caucuucguc cgcgucgccu acuacgccaa guggauccac     2160

aaggucaucc ucaccuacaa gcucuga                                         2187


<210>  5274
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt2) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5274
augggcaagg gcgaccccaa gaagccccgc ggcaagaugu ccuccuacgc cuucuucguc       60

cagaccugcc gcgaggagca caagaagaag caccccgacg ccuccgucaa cuucuccgag      120

uucuccaaga agugcuccga gcgcuggaag accauguccg ccaaggagaa gggcaaguuc      180

gaggacaugg ccaaggccga caaggcccgc uacgagcgcg agaugaagac cuacaucccc      240

cccaagggcg agaccaagaa gaaguucaag gaccccaacg cccccaagcg cccccccucc      300

gccuucuucc ucuucugcuc cgaguaccgc cccaagauca agggcgagca ccccggccuc      360

uccaucggcg acgucgccaa gaagcucggc gagaugugga acaacaccgc cgccgacgac      420

aagcagcccu acgagaagaa ggccgccaag cucaaggaga aguacgagaa ggacaucgcc      480

gccuaccgcg ccaagggcaa gcccgacgcc gccaagaagg gcgucgucaa ggccgagaag      540

uccaagaaga agaaggagga ggaggaggac gaggaggacg aggaggacga ggaggaggag      600

gaggacgagg aggacgagga cgaggaggag gacgacgacg acgaguga                   648


<210>  5275
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt2) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5275
augaacuucc uccucuccug gguccacugg acccucgccc uccuccucua ccuccaccac       60

gccaaguggu cccaggccgc ccccaccacc gagggcgagc agaaguccca cgaggucauc      120

aaguucaugg acgucuacca gcgcuccuac ugccgcccca ucgagacccu cgucgacauc      180

uuccaggagu accccgacga gaucgaguac aucuucaagc ccuccugcgu cccccucaug      240

cgcugcgccg gcugcugcaa cgacgaggcc cucgagugcg uccccaccuc cgaguccaac      300

aucaccaugc agaucaugcg caucaagccc caccaguccc agcacaucgg cgagaugucc      360

uuccuccagc acucccgcug cgagugccgc cccaagaagg accgcaccaa gcccgagaag      420

aaguccgucc gcggcaaggg caagggccag aagcgcaagc gcaagaaguc ccgcuucaag      480

uccugguccg uccacugcga gcccugcucc gagcgccgca agcaccucuu cguccaggac      540

ccccagaccu gcaagugcuc cugcaagaac accgacuccc gcugcaaggc ccgccagcuc      600

gagcucaacg agcgcaccug ccgcugcgac aagccccgcc gcuga                      645


<210>  5276
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt3) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5276
auggacagcg augagaccgg cuucgaacac uccgggcugu gggugucugu ccucgccgga       60

cuucuguugg gugcuugcca ggcacauccc aucccugacu caaguccauu acugcaauuu      120

ggcgggcagg uuagacagag guaccuauau acagaugacg cccagcaaac ugaggcgcac      180

cucgaaauuc gggaggaugg aacggugggc ggugcugccg accagagccc ggaaucccug      240

cuucagcuga aggcauugaa acccggggua auacagaucc ucggagugaa gaccucucgc      300

uuccuguguc aacgaccuga uggcgcccug uacggcucgc uccauuuuga cccagaggcu      360

ugcucauucc gugagagauu acuggaagau ggguauaacg ucuaccagag cgaggcacac      420

ggacuucccu ugcaucugcc ugguaauaaa aguccacaca gggaccccgc cccucggggc      480

ccagcucgcu uucuaccgcu ccccgggcug ccuccagccc uucccgaacc uccaggcauu      540

cuggcgcccc agccgccuga ugugggaucc ucugaccccu ugagcauggu uggugggucc      600

cagggaagau caccaaguua ugagagcuga                                       630


<210>  5277
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt3) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5277
augauguggg gcaccaagcu gcuccccgug cuucuguugc agcacgucuu acugcaucua       60

cuccugcuuc acguugccau cccuuacgcu gaggggcaaa agaagagaag gaacacacug      120

caugaguuca aaaagagcgc aaaaacuacg uugaccaagg aggacccacu ccugaagauu      180

aaaacaaaga aaguaaauuc cgccgaugaa ugcgcgaacc gguguauacg caaucgagga      240

uuuacuuuua ccugcaaggc uuucguguuc gacaaaucuc guaagagaug uuauugguac      300

ccguuuaacu caaugaguag cggugugaag aaaggcuucg ggcacgaguu ugaucuguau      360

gaaaauaagg acuacaucag gaacugcauu aucggaaaag gcgguuccua uaaggggaca      420

gucucuauua ccaaaucggg aaucaagugu cagcccugga acucaaugau accucaugag      480

cacagcuucc ucccaaguuc cuaccggggc aaagauuuac aggagaauua uugccgcaau      540

cccagaggcg aagaaggggg accuuggugu uuuacuucua acccagaagu gagguacgag      600

guuugcgaca ucccccagug uagcgaggug gaaugcauga cauguaaugg ugaguccuac      660

cggggcccua uggaucacac cgaaucaggg aagacgugcc aacgcuggga ccagcagacu      720

ccacaucgac acaaguuccu gccggagaga uaucccgaua aaggauuuga cgauaacuac      780

ugcaggaauc cugacggcaa gccacggccc ugguguuaua cccuugaucc ugacacacca      840

ugggaauacu gcgccauuaa aacuugugca cauagugccg ucaacgagac cgacgugccc      900

auggagacaa ccgaaugcau ccagggucaa ggggagggau aucguggcac gagcaauacu      960

auuuggaacg gcaucccgug ucagcgcugg gauucucagu acccucacaa gcacgacaua     1020

acacccgaaa acuucaaaug caaggauuug agagagaauu auuguaggaa cccagacggg     1080

gcugaauccc cuuggugcuu uaccacugau cccaauauuc ggguaggaua cuguucacag     1140

aucccaaagu gcgacguuag caguggucaa gauuguuacc gaggcaacgg gaaaaauuau     1200

augggaaacc ugucuaagac acgcuccggc cuaaccugca gcauguggga caaaaauaug     1260

gaggaucucc auagacacau uuucugggag cccgacgcau cgaagcugaa caaaaauuac     1320

ugcaggaacc cugaugacga cgcccauggu ccaugguguu auacggggaa uccgcuuauc     1380

cccugggauu acugcccuau cucucggugu gaaggcgaca ccacaccaac uauugugaac     1440

cuggaucacc ccgucauauc cugcgcuaag accaagcagu ugcgcguggu gaauggaauc     1500

ccuacacaga cuaccgucgg cuggaugguu ucacucaaau auagaaacaa gcauauuugu     1560

gggggaaguc ugaucaaaga gagcugggug uuaacagcca ggcaaugcuu cccagcgcgu     1620

aauaaggacc ugaaagauua cgaagcaugg cucgguauac acgacguaca cgagcggggc     1680

gaagagaagc gaaagcagau ucuuaacauc ucccagcugg uguaugggcc cgagggaucu     1740

gauuuggucc uacugaaacu cgccagaccg gcuauccugg acaacuuugu gagcaccauu     1800

gaucuuccuu cauacggcug uacuauccca gaaaagacga caugcaguau uuacgguugg     1860

ggguauaccg gccugauaaa ugccgacgga uugcucaggg uugcacaucu guacaucaug     1920

ggcaacgaga aauguuccca gcaccaucaa gggaagguga cuuuaaauga aagcgagcug     1980

ugcgcuggag ccgagaaaau ugguucuggc cccugugaag gggauuaugg aggcccucua     2040

aucugcgagc agcacaagau gcgcaugguc cucgguguga ucguacccgg gcggggcugc     2100

gcgauuccaa acagaccugg aauauucguu aggguggccu acuaugcaaa auggauccac     2160

aaggucauuc ugaccuacaa acuuuga                                         2187


<210>  5278
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt3) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5278
augggcaagg gggaccccaa aaagccuaga ggaaaaauga gcuccuacgc cuucuuugug       60

cagaccugca gggaggaaca caagaaaaag cauccagaug cuucugucaa cuucucagag      120

uuuaguaaga aauguagcga acgguggaag acaauguccg caaaagagaa ggguaaauuc      180

gaagacaugg ccaaggcgga uaaggcucgc uaugagcgag agaugaaaac uuacaucccg      240

cccaagggcg aaacgaaaaa gaaauuuaag gacccuaaug ccccaaaacg ucccccuucu      300

gcauucuuuc uguucugcuc ggaguauaga ccaaagauua agggggaaca ccccggacuc      360

ucaauaggcg auguugccaa gaaacuuggu gagaugugga acaauaccgc ugcagacgau      420

aaacaaccuu acgagaagaa agccgcuaag cugaaggaaa aauaugagaa ggacaucgcc      480

gcguacaggg caaaagggaa gccagaugcc gcuaaaaagg gagugguaaa ggccgagaaa      540

agcaagaaaa agaaagaaga agaggaggac gaagaggaug aagaggacga agaggaggaa      600

gaggaugaag aggacgaaga cgaggaggaa gaugacgaug acgaguga                   648


<210>  5279
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt3) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5279
augaacuucc ugcucagcug ggugcacugg acccuugccc uguuguuaua ccugcaucac       60

gcuaaguggu cccaggcagc ccccacaacu gagggcgaac aaaaaucuca ugaggucauc      120

aaguuuaugg acguuuauca gagaucauac ugcaggccua uugaaacgcu aguggauaua      180

uuccaggagu auccagacga aaucgaguac auuuuuaaac cgaguugugu accccucaug      240

cggugcgcgg gguguugcaa ugaugaggcu cuggaaugug ugccuaccag cgaguccaac      300

aucacaaugc agauuaugcg caucaagcca caccaaucuc agcauauagg agaaaugucg      360

uuccuucagc acucacgaug cgagugucgu cccaaaaagg acagaacuaa gccugagaaa      420

aagagcguca gggguaaagg caaggggcag aaacggaagc gcaagaaaag uagauuuaag      480

uccuggucug ugcacugcga accauguagc gagaggcgga aacaucuguu cguucaagau      540

ccccagaccu gcaaguguuc cugcaaaaau acagacucac gcugcaaggc ccgacaguug      600

gaacucaacg agagaaccug uaggugcgau aaaccucggc guuga                      645


<210>  5280
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt4) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5280
auggacagcg acgagaccgg cuucgagcac agcggccugu gggugagcgu gcuggccggc       60

cugcugcugg gcgccugcca ggcccacccc auccccgaca gcagcccccu gcugcaguuc      120

ggcggccagg ugagacagag auaccuguac accgacgacg cccagcagac cgaggcccac      180

cuggagauca gagaggacgg caccgugggc ggcgccgccg accagagccc cgagagccug      240

cugcagcuga aggcccugaa gcccggcgug auccagaucc ugggcgugaa gaccagcaga      300

uuccugugcc agagacccga cggcgcccug uacggcagcc ugcacuucga ccccgaggcc      360

ugcagcuuca gagagagacu gcuggaggac ggcuacaacg uguaccagag cgaggcccac      420

ggccugcccc ugcaccugcc cggcaacaag agcccccaca gagaccccgc ccccagaggc      480

cccgccagau uccugccccu gcccggccug ccccccgccc ugcccgagcc ccccggcauc      540

cuggcccccc agccccccga cgugggcagc agcgaccccc ugagcauggu gggcggcagc      600

cagggcagaa gccccagcua cgagagcuga                                       630


<210>  5281
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt4) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5281
augauguggg gcaccaagcu gcugcccgug cugcugcugc agcacgugcu gcugcaccug       60

cugcugcugc acguggccau ccccuacgcc gagggccaga agaagagaag aaacacccug      120

cacgaguuca agaagagcgc caagaccacc cugaccaagg aggacccccu gcugaagauc      180

aagaccaaga aggugaacag cgccgacgag ugcgccaaca gaugcaucag aaacagaggc      240

uucaccuuca ccugcaaggc cuucguguuc gacaagagca gaaagagaug cuacugguac      300

cccuucaaca gcaugagcag cggcgugaag aagggcuucg gccacgaguu cgaccuguac      360

gagaacaagg acuacaucag aaacugcauc aucggcaagg gcggcagcua caagggcacc      420

gugagcauca ccaagagcgg caucaagugc cagcccugga acagcaugau cccccacgag      480

cacagcuucc ugcccagcag cuacagaggc aaggaccugc aggagaacua cugcagaaac      540

cccagaggcg aggagggcgg ccccuggugc uucaccagca accccgaggu gagauacgag      600

gugugcgaca ucccccagug cagcgaggug gagugcauga ccugcaacgg cgagagcuac      660

agaggcccca uggaccacac cgagagcggc aagaccugcc agagauggga ccagcagacc      720

ccccacagac acaaguuccu gcccgagaga uaccccgaca agggcuucga cgacaacuac      780

ugcagaaacc ccgacggcaa gcccagaccc uggugcuaca cccuggaccc cgacaccccc      840

ugggaguacu gcgccaucaa gaccugcgcc cacagcgccg ugaacgagac cgacgugccc      900

auggagacca ccgagugcau ccagggccag ggcgagggcu acagaggcac cagcaacacc      960

aucuggaacg gcauccccug ccagagaugg gacagccagu acccccacaa gcacgacauc     1020

acccccgaga acuucaagug caaggaccug agagagaacu acugcagaaa ccccgacggc     1080

gccgagagcc ccuggugcuu caccaccgac cccaacauca gagugggcua cugcagccag     1140

auccccaagu gcgacgugag cagcggccag gacugcuaca gaggcaacgg caagaacuac     1200

augggcaacc ugagcaagac cagaagcggc cugaccugca gcauguggga caagaacaug     1260

gaggaccugc acagacacau cuucugggag cccgacgcca gcaagcugaa caagaacuac     1320

ugcagaaacc ccgacgacga cgcccacggc cccuggugcu acaccggcaa cccccugauc     1380

cccugggacu acugccccau cagcagaugc gagggcgaca ccacccccac caucgugaac     1440

cuggaccacc ccgugaucag cugcgccaag accaagcagc ugagaguggu gaacggcauc     1500

cccacccaga ccaccguggg cuggauggug agccugaagu acagaaacaa gcacaucugc     1560

ggcggcagcc ugaucaagga gagcugggug cugaccgcca gacagugcuu ccccgccaga     1620

aacaaggacc ugaaggacua cgaggccugg cugggcaucc acgacgugca cgagagaggc     1680

gaggagaaga gaaagcagau ccugaacauc agccagcugg uguacggccc cgagggcagc     1740

gaccuggugc ugcugaagcu ggccagaccc gccauccugg acaacuucgu gagcaccauc     1800

gaccugccca gcuacggcug caccaucccc gagaagacca ccugcagcau cuacggcugg     1860

ggcuacaccg gccugaucaa cgccgacggc cugcugagag uggcccaccu guacaucaug     1920

ggcaacgaga agugcagcca gcaccaccag ggcaagguga cccugaacga gagcgagcug     1980

ugcgccggcg ccgagaagau cggcagcggc cccugcgagg gcgacuacgg cggcccccug     2040

aucugcgagc agcacaagau gagaauggug cugggcguga ucgugcccgg cagaggcugc     2100

gccaucccca acagacccgg caucuucgug agaguggccu acuacgccaa guggauccac     2160

aaggugaucc ugaccuacaa gcuguga                                         2187


<210>  5282
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt4) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5282
augggcaagg gcgaccccaa gaagcccaga ggcaagauga gcagcuacgc cuucuucgug       60

cagaccugca gagaggagca caagaagaag caccccgacg ccagcgugaa cuucagcgag      120

uucagcaaga agugcagcga gagauggaag accaugagcg ccaaggagaa gggcaaguuc      180

gaggacaugg ccaaggccga caaggccaga uacgagagag agaugaagac cuacaucccc      240

cccaagggcg agaccaagaa gaaguucaag gaccccaacg cccccaagag accccccagc      300

gccuucuucc uguucugcag cgaguacaga cccaagauca agggcgagca ccccggccug      360

agcaucggcg acguggccaa gaagcugggc gagaugugga acaacaccgc cgccgacgac      420

aagcagcccu acgagaagaa ggccgccaag cugaaggaga aguacgagaa ggacaucgcc      480

gccuacagag ccaagggcaa gcccgacgcc gccaagaagg gcguggugaa ggccgagaag      540

agcaagaaga agaaggagga ggaggaggac gaggaggacg aggaggacga ggaggaggag      600

gaggacgagg aggacgagga cgaggaggag gacgacgacg acgaguga                   648


<210>  5283
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt4) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5283
augaacuucc ugcugagcug ggugcacugg acccuggccc ugcugcugua ccugcaccac       60

gccaagugga gccaggccgc ccccaccacc gagggcgagc agaagagcca cgaggugauc      120

aaguucaugg acguguacca gagaagcuac ugcagaccca ucgagacccu gguggacauc      180

uuccaggagu accccgacga gaucgaguac aucuucaagc ccagcugcgu gccccugaug      240

agaugcgccg gcugcugcaa cgacgaggcc cuggagugcg ugcccaccag cgagagcaac      300

aucaccaugc agaucaugag aaucaagccc caccagagcc agcacaucgg cgagaugagc      360

uuccugcagc acagcagaug cgagugcaga cccaagaagg acagaaccaa gcccgagaag      420

aagagcguga gaggcaaggg caagggccag aagagaaaga gaaagaagag cagauucaag      480

agcuggagcg ugcacugcga gcccugcagc gagagaagaa agcaccuguu cgugcaggac      540

ccccagaccu gcaagugcag cugcaagaac accgacagca gaugcaaggc cagacagcug      600

gagcugaacg agagaaccug cagaugcgac aagcccagaa gauga                      645


<210>  5284
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt5) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5284
auggacagcg augagaccgg cuucgaacac uccgggcugu gggugucugu ccucgccgga       60

cugcuucugg gcgcuugcca ggcccauccc aucccugaca gcuccccgcu ccugcaauuu      120

gggggacagg uuagacagcg guaccuuuau acagaugacg cgcagcaaac ggaggcucac      180

cuggaaauuc gcgaggaugg caccgugggc ggagccgccg accagucucc cgaaagccuc      240

cugcagcuga aggcucucaa accuggcgug auccagauuc ugggcgucaa gacauccaga      300

uuccuuuguc aacggcccga uggggcccug uacggaucuc uccauuuuga cccugaggcu      360

ugcagcuucc gcgagagacu gcuugaagau ggcuauaacg uguaccaguc cgaggcccac      420

gggcugcccc uccaucugcc uggaaauaaa agcccgcacc gggaccccgc gccucgcggc      480

cccgccagau uucugccucu ccccgggcug ccgccugccc uucccgaacc ucccggaauc      540

cuggcucccc agccuccgga uguugggucu uccgaccccc ucagcauggu gggcgggucu      600

cagggacggu ccccuagcua ugagucuuga                                       630


<210>  5285
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt5) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5285
augauguggg gcaccaagcu gcuccccgug cugcuucugc agcacguccu ccugcaucuu       60

cugcuccugc acguugccau cccuuacgcu gaggggcaga aaaagagacg gaacacacug      120

caugaguuca aaaagagcgc caaaacgacc cucacaaagg aagacccgcu gcuuaagauu      180

aaaaccaaga aagucaauuc cgcggaugaa ugcgcuaacc gcuguaucag aaaucgggga      240

uuuacauuua ccugcaaggc cuucguguuc gacaaaucuc gcaagagaug uuauugguac      300

cccuuuaaca gcauguccuc uggcgugaag aaaggguucg gacacgaguu ugaucuguau      360

gaaaauaagg acuacauucg gaacugcauc auuggcaaag ggggaagcua uaagggcaca      420

guguccauca ccaaaucugg caucaagugu caaccuugga auagcaugau uccccaugag      480

cacuccuucc ucccuagcuc uuaccgcggg aaagaucugc aggagaacua uugcagaaau      540

ccccggggag aagagggcgg gccuuggugu uuuacgucca acccggaagu ucgcuacgag      600

gugugcgaca ucccccagug uagcgagguc gaaugcauga ccuguaaugg agagucuuac      660

agaggcccua uggaucacac agaauccggg aagaccugcc aacgguggga ccagcagaca      720

ccccaucgcc acaaguuccu uccugagaga uaucccgaua aaggauuuga cgauaacuac      780

ugccggaauc cggacggcaa gccucgcccc ugguguuaua cccuggaucc ugacacgccc      840

ugggaauacu gcgccauuaa aacaugugcu cauagcgccg ugaacgagac cgacguuccc      900

auggagacaa ccgaaugcau ccagggccaa ggggagggau auagaggcac cucuaauaca      960

auuuggaacg ggaucccuug ucagcggugg gauucccagu acccgcacaa gcacgacauu     1020

acgcccgaaa acuucaaaug caaggaucuc agagagaauu auugucgcaa cccugacgga     1080

gcugaaagcc ccuggugcuu uaccacagau ccuaauaucc gggugggcua cuguucccag     1140

auccccaagu gcgacgucuc uagcgggcaa gauuguuaca gaggaaacgg caaaaauuau     1200

augggcaacc uguccaagac ccgcagcggg cugacaugcu cuauguggga caaaaauaug     1260

gaggaucucc aucggcacau uuucugggag ccggacgccu ccaagcugaa caaaaauuac     1320

ugcagaaacc cugaugacga cgcgcaugga cccugguguu auaccggcaa uccucuuauc     1380

cccugggauu acugcccuau uagccgcugu gaaggggaca cgacacccac caucgugaac     1440

cuggaucacc cggugauuuc uugcgccaag accaagcagc uccgggucgu uaauggaauc     1500

ccuacacaga ccacaguggg cuggauggug agccugaaau auagaaacaa gcauaucugu     1560

gggggcuccc uuauuaaaga gucuuggguc cugacggcuc gccaaugcuu ccccgcccgg     1620

aauaaggacc ucaaagauua cgaggcuugg cugggaaucc acgacgugca cgaaagaggc     1680

gaagagaagc gcaagcagau ucugaacauc agccagcucg uuuaugggcc cgagggaucc     1740

gaucuggugc uucugaaacu cgcccggccu gcgauucugg acaacuuugu cagcaccauc     1800

gaucuuccgu cuuacggcug uacaaucccc gaaaagacca caugcuccau uuacgggugg     1860

ggauauaccg gccugaucaa ugccgacggg cuccugagag uggcucaucu guacauuaug     1920

ggcaacgaga aauguagcca gcaccaucaa ggaaagguua cgcucaauga aucugagcug     1980

ugcgccggcg cugagaaaau cggguccgga ccuugugaag gcgauuaugg gggaccccuu     2040

auuugcgagc agcacaagau gcggauggug cugggcguca ucgugccugg gcgcggcugc     2100

gccauuccca acagaccugg aaucuucguc cggguggccu acuaugcuaa auggauccac     2160

aagguuauuc ucaccuacaa gcuguga                                         2187


<210>  5286
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt5) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5286
augggcaagg gggaccccaa aaagccuaga ggaaaaauga gcuccuacgc cuucuuugug       60

cagaccugcc gggaggaaca caagaaaaag cauccggaug cuucugucaa cuucagcgag      120

uuuuccaaga aauguucuga acgcuggaag acaaugagcg ccaaagagaa gggcaaauuc      180

gaagacaugg cgaaggcuga uaaggccaga uaugagcggg agaugaaaac guacauuccc      240

ccuaaggggg aaaccaaaaa gaaauuuaag gaccccaaug ccccuaaaag acccccuucc      300

gcuuucuuuc uguucugcuc ugaguaucgc ccgaagauca agggagaaca ccccggccuc      360

agcaucgggg auguugccaa aaagcuggga gagaugugga acaauacagc ugccgacgau      420

aaacaaccuu acgagaagaa agcggccaaa cuuaaggaaa aguaugagaa ggacauugcu      480

gccuaccggg cuaaaggcaa gcccgaugcc gcgaaaaagg gcguggugaa ggccgaaaaa      540

uccaagaaaa agaaagagga agaggaggac gaagaggaug aagaggacga agaggaggaa      600

gaggaugaag aggacgaaga cgaggaggaa gaugacgaug acgaguga                   648


<210>  5287
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt5) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5287
augaacuucc ugcucagcug ggugcacugg acccuggccc uucugcucua ccugcaucac       60

gcuaaguggu cccaggccgc gcccacaacg gagggcgaac aaaaaucuca ugaggucauc      120

aaguuuaugg acguuuauca gagaagcuac ugccggccua uugaaacccu uguggauauc      180

uuccaggagu auccggacga aauugaguac aucuuuaaac ccuccugugu gccucugaug      240

cgcugcgcug gguguugcaa ugaugaggcc cucgaaugug uccccacauc ugagagcaac      300

auuaccaugc agaucaugag aaucaagccu caccaauccc agcauauugg agaaaugucu      360

uuccugcagc acagccggug cgagugucgc cccaaaaagg acagaacaaa gccugagaaa      420

aaguccgugc ggggcaaagg gaagggacag aaacgcaaga gaaagaaaag ccgguuuaag      480

ucuugguccg uucacugcga accguguagc gagcgcagaa aacaucuguu cgugcaagau      540

ccccagaccu gcaaguguuc uugcaaaaau acagacuccc ggugcaaggc ccgccagcuc      600

gaacugaacg agagaaccug ucggugcgau aaaccucgca gauga                      645


<210>  5288
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt6) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5288
auggauucag augaaacagg auuugaacac ucaggauuau gggucucagu uuuagcagga       60

cuauuacuag gagcauguca agcacaucca auaccagacu caagcccauu auuacaauuu      120

ggaggacaag uaagacaaag auauuuauau acagaugacg cacaacaaac agaagcacau      180

uuagaaauaa gagaagacgg cacaguagga ggagcagcag aucaaucacc agaaucacua      240

uuacaauuaa aagcauuaaa accaggagua auacaaauau uaggaguaaa aacaucaaga      300

uucuuaugcc aaagaccuga cggagcauua uaugguucac uacacuuuga cccagaagca      360

uguucauuca gagaaagacu acuagaagac ggauauaaug uuuaccaauc ugaagcacau      420

ggauuaccac uacacuuacc aggaaauaaa ucaccacacc gagacccagc accacgagga      480

ccagcaagau uccuaccacu accaggauua ccaccagcau uaccagaacc accaggaaua      540

cuagcuccac aaccaccaga cguaggaucc ucagauccau uaucaauggu aggaggaucu      600

caagguagaa gucccucaua cgaaucauaa                                       630


<210>  5289
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt6) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5289
augauguggg gaacaaaacu auuaccagua uuauuauuac aacaugucuu auuacauuua       60

cuucuacuac auguugcaau acccuaugcc gaaggacaaa agaaaagaag aaacacucuu      120

cacgaguuca agaaaagcgc aaaaacaaca uuaacaaaag aagacccacu acuaaaaaua      180

aaaacaaaga aaguaaacuc agcagaugaa ugugccaaca gauguauuag aaaccggggu      240

uuuacuuuua caugcaaagc cuucguauuc gauaaaucaa ggaaaagaug cuacugguau      300

ccauucaauu caaugucauc cggagucaag aaaggauucg gccaugaauu ugaccuauac      360

gaaaauaaag auuauaucag aaacuguaua auaggaaaag gugguucaua caaaggaaca      420

guaucaauaa caaaaagcgg uauuaaaugu caacccugga acucuaugau uccucaugaa      480

cauucauuuu uaccaucauc auacagaggu aaagacuuac aagaaaauua cugcagaaau      540

ccaaggggag aagaaggcgg accauggugc uuuacaucaa aucccgaagu aagauaugaa      600

guaugcgaca uaccacaaug uagugaaguu gaauguauga cauguaaugg agaaagcuac      660

agagguccaa uggaucauac agaaucagga aaaacaugcc aaagauggga ucaacaaaca      720

ccgcauagac auaaauuuuu accagaaaga uauccagaua aaggauucga ugacaauuac      780

uguaggaauc ccgacggaaa accacgacca uggugcuaua cacuagaccc ugauacucca      840

ugggaauauu gcgcuauaaa aacuugugca cauucagcag uaaacgaaac cgacguacca      900

auggaaacca cugaauguau acaagggcaa ggagaaggau acagaggaac aucaaauaca      960

auauggaacg gaauacccug ucaaagaugg gauagccaau auccacauaa acacgacaua     1020

accccagaaa acuuuaaaug uaaagaucua agagaaaauu acugcagaaa ucccgauggc     1080

gcagaaucac cauggugcuu cacaacagau cccaacauaa gagucggaua uugcucccag     1140

auuccuaaau gugauguaag cuccgggcaa gacugcuacc gaggcaacgg uaaaaauuac     1200

augggaaacu uaaguaaaac aagaucagga uuaacaugca guauguggga uaaaaauaug     1260

gaggacuuac auagacauau auucugggaa ccagaugcau caaaacuuaa caaaaauuau     1320

ugcagaaacc cagacgacga ugcacacgga ccaugguguu auacaggaaa uccacuuaua     1380

ccaugggacu auuguccaau aucacgaugc gaaggagaua caacaccaac aauaguaaac     1440

uuagaucauc caguaauaag uugcgcaaaa acuaaacaau uacgaguugu uaacggaaua     1500

ccaacacaaa cuacagucgg auggaugguu ucauuaaaau auagaaacaa acacauaugc     1560

ggaggauccc uuauaaaaga auccugggua uuaacagcaa gacaauguuu uccagccaga     1620

aauaaagauc ucaaagacua cgaagcaugg uuaggcauac acgauguaca ugaacgagga     1680

gaagaaaaac gaaaacaaau auuaaauaua agccagcuag uuuauggacc agaaggaucg     1740

gacuuaguac uauuaaaacu ugcaagacca gcaauccuag acaauuuugu cucaacaauc     1800

gacuuacccu cauauggaug cacuauuccg gagaaaacaa caugcuccau auacggaugg     1860

ggauauacag gauugauaaa ugcagaugga uuacuaagag uagcacaucu auacauaaug     1920

ggaaaugaaa aauguucaca acaccaucaa ggaaaaguaa cacuaaacga aagcgaauua     1980

ugugcaggcg cagagaaaau aggcagugga ccaugugaag gagauuacgg uggaccacua     2040

auaugcgaac aacauaaaau gagaaugguc cuaggaguaa uaguccccgg aagaggaugu     2100

gcaauaccaa aucgaccggg cauauuugua agaguagcau acuacgcaaa auggauacac     2160

aaaguaauac uaacauacaa acuauaa                                         2187


<210>  5290
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt6) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5290
augggaaaag gagacccaaa aaaaccaaga ggaaaaaugu caagcuacgc auucuucgua       60

caaacaugca gagaagaaca caaaaaaaaa cacccagacg caagcguaaa cuucagcgaa      120

uucagcaaaa aauguucaga aagauggaaa acaaugagcg caaaagaaaa aggaaaauuc      180

gaagacaugg caaaagcaga caaagcaaga uacgaaagag aaaugaaaac auacauacca      240

ccaaaaggag aaacaaaaaa aaaauucaaa gacccaaacg cgccaaaaag accaccauca      300

gcauucuucu uauucugcag ugaauacaga ccaaaaauaa aaggagaaca cccaggacua      360

aguauaggag acguagcaaa aaaacuagga gaaaugugga acaacacagc agcagacgac      420

aaacaaccau acgaaaaaaa agcagcaaaa cuaaaagaaa aauacgaaaa agacauagcg      480

gcauacagag caaaaggaaa accagacgca gcaaaaaaag gaguaguaaa agcagaaaaa      540

aguaaaaaaa aaaaagaaga agaagaagac gaagaagacg aagaagacga agaagaagaa      600

gaagacgaag aagacgaaga cgaagaagaa gacgacgacg acgaauaa                   648


<210>  5291
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt6) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5291
augaacuucc uauuaagcug gguacacugg acacuagcac uacuacuaua cuuacaccac       60

gccaaaugga gccaagcagc accaacaaca gaaggagaac aaaaaucaca cgaaguaaua      120

aaauucaugg acguauacca aagaucauac uguagaccaa uagaaacacu aguagacaua      180

uuccaagaau acccagacga aauagaauac auauucaaac caucaugcgu accacuaaug      240

agaugcgcag gaugcugcaa cgacgaagca cuagaaugcg uaccaacauc agaaucaaac      300

auaacaaugc aaauaaugag aauaaaacca caccaaaguc aacacauagg agaaaugagu      360

uuccuacaac acucaagaug cgaaugcaga ccaaaaaaag acagaacaaa accagaaaaa      420

aaaucaguaa gaggaaaagg aaaaggccaa aaaagaaaaa gaaaaaaauc aagauucaaa      480

agcuggucag uacacuguga accauguuca gaaagaagaa aacaccuauu cguacaagac      540

ccacaaacau gcaaaugcag uugcaaaaac acagacucaa gaugcaaagc aagacaacua      600

gaauuaaaug aacgaacaug cagaugcgac aaaccaagaa gauaa                      645


<210>  5292
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt7) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5292
auggacagcg augagaccgg cuucgaacac uccgggcugu gggugagugu ccucgccggu       60

cuguugcugg gcgcaugcca ggcccauccc aucccagaca gcuccccgcu ccugcaauuu      120

gggggccagg ugaggcagcg guacuuguau acugaugacg cgcagcaaac cgaggcccac      180

cuggaaauuc gcgaggaugg uacgguaggg ggcgcagccg accagagucc cgaaagccuc      240

cugcagcuga aggcacucaa accaggcgug auccagauuc ugggggucaa gacuuccagg      300

uucuuguguc aacggcccga uggugcccug uacggcagcc uccauuuuga cccagaggcg      360

ugcuccuucc gcgagaggcu gcuggaagau ggguauaacg uguaccagag ugaggcccac      420

ggcuugcccc uccaucugcc agguaauaaa agcccgcacc gggaccccgc accacgcggg      480

cccgccaggu uucugccacu ccccggccug ccgcccgccu ugccagaacc cccaggcauc      540

cuggcacccc agccaccgga uguggggucc agcgaccccc ucaguauggu cgguggcucc      600

caggggcgga gcccauccua ugagaguuga                                       630


<210>  5293
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt7) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5293
augauguggg gcaccaagcu gcuccccgug cuguugcugc agcacguccu ccugcauuug       60

cugcuccugc acguggccau cccauacgca gaggggcaga aaaagaggcg gaacacucug      120

caugaguuca aaaagagcgc caaaaccacg cucacuaagg aggacccgcu guugaagauu      180

aaaaccaaga aaguaaauuc cgcggaugaa ugcgccaacc gcuguaucag gaaucggggu      240

uuuaccuuca cuugcaaggc auuuguguuc gacaaaaguc gcaagaggug uuauugguac      300

cccuuuaaca gcauguccag uggcgucaaa aagggguucg gccacgaguu ugaucuguau      360

gaaaauaagg acuacauucg gaacugcauc auugguaaag ggggcagcua uaagggcacc      420

guguccauca cgaaaagcgg gaucaagugu caaccaugga acuccaugau uccccaugag      480

cacaguuucc ucccaagcuc cuaccgcggu aaagaucugc aggagaauua uugcaggaau      540

ccccggggcg aagaaggggg cccauggugu uuuacuagca acccggaagu gcgcuacgag      600

gucugcgaca ucccccagug uagugaggug gaaugcauga ccugcaaugg ugaguccuac      660

agggggccaa uggaucacac ugaaagcggc aagaccuguc aacgguggga ccagcagacu      720

ccccaucgcc acaaguuccu gccagagagg uaucccgaua aaggcuuuga cgauaacuac      780

ugccggaauc cggacgggaa gccccgccca ugguguuaua cguuggaucc cgacacucca      840

ugggaauacu gcgccauuaa aaccugugca cauuccgccg uaaacgagac ugacgugccc      900

auggagacca ccgaaugcau ccagggucaa ggcgaggggu auaggggcac caguaauacg      960

auuuggaacg guaucccaug ucagcggugg gauagccagu acccgcacaa gcacgacauu     1020

acccccgaaa acuucaaaug caaggaucuc cgcgagaauu auuguaggaa cccagacggc     1080

gcggaauccc ccuggugcuu cacuaccgau ccaaauaucc gggucgggua cugcagccag     1140

auccccaagu gugacgugag uuccggccaa gauugcuaca gggggaacgg uaaaaauuau     1200

augggcaacc ugagcaagac ccgcaguggg cugacuuguu ccauguggga caaaaauaug     1260

gaggaucucc aucggcacau cuuuugggag ccggacgcca gcaagcugaa caaaaauuac     1320

ugcaggaacc cagaugacga cgcacauggc cccugguguu auacggguaa ucccuugauu     1380

ccaugggauu acugccccau uagccgcugu gaaggcgaca ccacuccaac caucgugaac     1440

cuggaucacc cggucauuuc cugcgccaag accaagcagc uccggguggu aaaugggauc     1500

cccacucaga cgaccguggg cuggaugguc agucugaaau auaggaacaa gcauaucugu     1560

gggggcagcc ugauuaaaga guccugggug uugacugccc gccaaugcuu cccagcacgg     1620

aauaaggacc ucaaagauua cgaagccugg cuggguaucc acgacgugca cgagaggggc     1680

gaagagaagc ggaaacagau ucugaacauc agccagcucg ucuaugggcc cgaggguagu     1740

gaucuggugu ugcugaagcu cgcgcgccca gccauucugg acaacuuugu auccaccauc     1800

gaucugccca gcuacggcug uacuaucccg gaaaagacca cgugcuccau uuacgggugg     1860

ggcuauaccg gguugaucaa ugcagacggc cuccugaggg uggcccaucu guacauuaug     1920

gguaacgaga aaugcaguca gcaccaucaa gggaagguca cucucaauga aagcgagcug     1980

ugugcaggcg ccgagaaaau cggcuccggg ccaugcgaag gugauuaugg cgggcccuug     2040

auuugugagc agcacaagau gcggauggug cugggcguca ucgugccagg ucgcgggugc     2100

gccauuccca acaggccggg caucuucgug cggguagcgu acuaugcaaa auggauccac     2160

aaggugauuc ucaccuacaa gcuguga                                         2187


<210>  5294
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt7) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5294
augggcaagg gggaccccaa aaagccaagg gguaaaauga gcuccuacgc cuucuuugug       60

cagaccugcc gggaggaaca caagaaaaag cauccggaug caagugucaa cuucagcgag      120

uuuuccaaga aauguaguga acgcuggaag acuaugagcg ccaaagagaa gggcaaauuc      180

gaagacaugg cgaaggccga uaaagcaagg uaugagcggg agaugaagac cuacauuccc      240

ccaaaggggg aaacgaaaaa gaaauuuaag gaccccaaug ccccaaaaag gcccccaucc      300

gcauucuuuc uguucugcag cgaguaucgc ccgaagauca agggcgaaca ccccggucuc      360

uccaucgggg auguggccaa aaagcugggc gagaugugga acaauacugc ggccgacgau      420

aaacaaccau acgagaagaa agcagccaag uugaaggaaa aauaugagaa ggacauugcc      480

gcauaccggg ccaaaggcaa gcccgaugcg gccaaaaagg ggguagugaa ggcagagaaa      540

aguaagaaaa agaaagaaga agaggaggac gaagaggaug aagaggacga agaggaggaa      600

gaggaugaag aggacgaaga cgaggaggaa gaugacgaug acgaguga                   648


<210>  5295
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt7) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5295
augaacuucc ugcucagcug ggugcacugg acccuggccu ugcugcucua ccugcaucac       60

gcaaaguggu cccaggccgc gcccacuacc gagggcgaac agaaaaguca ugaggucauc      120

aaguuuaugg acguguauca aaggagcuac ugccggccaa uugaaacguu gguagauauc      180

uuccaggagu auccggacga aauugaguac aucuuuaaac ccuccugugu gccacugaug      240

cgcugcgccg gguguugcaa ugaugaggca cucgaaugug uccccaccag ugagagcaac      300

auuacuaugc agaucaugag gaucaagcca caccaauccc agcauauugg ugaaaugagc      360

uuccugcagc acucccggug cgagugucgc cccaaaaagg acaggaccaa gccagagaaa      420

aagagugugc ggggcaaagg gaagggccag aaacgcaaga ggaaaaagag ccgguuuaag      480

uccuggagcg ugcacugcga accguguagu gagcgcagga aacaucuguu cguccaagau      540

ccccagacuu gcaagugcuc cuguaaaaau accgacagcc ggugcaaggc ccgccagcuc      600

gaacugaacg agaggacgug ucggugcgau aaaccaaggc gcuga                      645


<210>  5296
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt8) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5296
auggacucug acgaaaccgg cuucgaacac uccggacucu gggucuccgu ccucgccggc       60

cuccuccuag gcgccugcca agcccacccc auccccgacu cauccccacu ccuacaauuc      120

ggcggccaag uccgucaacg cuaccucuau accgaugacg cccaacaaac cgaagcccac      180

cucgaaaucc gcgaagacgg aaccgucggc ggcgccgcug accaaucacc cgaaucccuc      240

cuccaacuca aagcacucaa acccggcgua auccaaaucc ucggcguaaa aaccucacga      300

uuucuauguc aaagacccga cggagcccua uacggcucuc uacacuucga cccagaagca      360

ugcuccuucc gcgaacgacu ccucgaagac ggauacaacg ucuaccaauc agaagcccac      420

ggccuacccc uccaccuccc cggcaacaaa ucuccccacc gcgaccccgc accccgcggc      480

cccgcccgcu uccucccccu ccccggccua cccccagccc uacccgaacc acccggcaua      540

cucgcacccc aaccacccga cgucggcucc uccgaccccc uauccauggu cggcggcucc      600

caaggccgcu cccccucaua cgaaucuuaa                                       630


<210>  5297
<211>  1993
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt8) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5297
augauguggg gcacgaaacu gcucccagua uugcucuugc aacacguccu acuccaccuu       60

cuacugcuac acgucgcuau acccuaugcc gaaggacaaa agaaacgucg caacacccua      120

cacgaauuua agaaaagcgc caagaccaca cucacuaaag aagauccccu acucaaaaua      180

aagaccaaaa aggugaacuc ggcugacgaa ugcgccaacc gaugcauccg aaacagaggc      240

uucacuuuua ccugcaaagc cuucguuuuc gacaagagcc gaaaacgaug cuacugguac      300

ccauucaaca gcauguccuc cgggguaaag aaaggcuucg gacaugaguu cgaucuauac      360

gaaaauaaag acuacauaag aaacugcaua aucggcaaag gaggguccua caaaggcaca      420

gucagcauca caaagucagg gaucaaaugc caacccugga acuccaugau accacacgag      480

cacaguuucc ucccuaguag cuaccgagga aaagaccucc aggagaacua cugccgcaac      540

ccccgcgggg aagaaggcgg accuuggugc uucacaagca accccgaggu ccgcuacgag      600

gucugcgaca ucccccaaug cagcgaaguc gagugcauga ccuguaacgg agaaucauac      660

cgaggcccaa uggaucacac cgaauccgga aaaacaugcc aacgauggga ccaacaaaca      720

ccgcaccgac acaaguuccu ccccgaacgg uaccccgaca aaggauucga cgacaacuac      780

ugccgcaacc ccgacggaaa accacgacca uggugcuaca cgcucgaccc ggacaccccc      840

ugggaauacu gcgccaucaa aaccugcgca cacucagcgg ugaacgaaac cgauguacca      900

auggaaacaa ccgaaugcau ccaaggacaa ggagagggcu acaggggcac gucaaauacc      960

aucuggaacg gcauaccaug ccagcgcugg gacagucagu acccccacaa acacgacaua     1020

acccccgaaa acuucaaaug caaagaccuc agagaaaacu acugccgcaa ccccgacggc     1080

gccgaauccc ccugguguuu cacaaccgac ccaaacaucc gcgugggcua cugcucacaa     1140

auccccaagu gcgacguauc aagcggccaa gacugcuauc gcgggaacgg caaaaacuac     1200

augggaaacc ucucaaagac cagaagcggc cuaacaugcu caauguggga caaaaacaug     1260

gaggaccucc accggcacau cuuuugggaa cccgacgcuu ccaaacucaa caaaaacuac     1320

ugccgaaacc ccgacgacga ugcacacggc ccauggugcu acacaggcaa cccccugaua     1380

cccugggacu acugccccau cuccagaugc gagggcgaca caacaccgac caucguaaau     1440

cucgaccacc ccguaaucuc cugcgccaaa acaaaacaac uaagggucgu gaacggaauc     1500

cccacccaaa caacaguggg cuggaugguc agccucaaau acagaaacaa gcacaucugc     1560

ggcggcuccc ucaucaagga aagcugggua cuaacagcca ggcaaugcuu ccccgccaga     1620

aauaaagauc uaaaagacua cgaagccugg cuaggcaucc augacgucca cgaacgcggc     1680

gaggagaaac gaaaacaaau ucucaacauc ucucaacucg ucuauggacc agaagggagc     1740

gaccucguuc uucugaaacu cgcccggccc gcaaucuuag acaacuucgu cagcacaauc     1800

gaccuccccu cauacggaug caccauccca gaaaagacaa ccugcagcau auacggaugg     1860

ggcuacaccg gccugaucaa cgcagacggc cuucucagag ucgcccaucu cuacaucaug     1920

ggaaacgaaa aaugcagcca acaccaccaa ggcaaaguaa cgcucaacga auccgaacuc     1980

ugcgccggag cag                                                        1993


<210>  5298
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt8) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5298
auggggaaag gggacccgaa aaagccaaga ggaaagaugu cgagcuaugc cuuuuucgug       60

caaacgugca gggaagaaca caagaaaaag cacccggacg cgagcgugaa cuuuagcgag      120

uucucgaaaa agugcucaga aagguggaag accaugagcg cgaaagaaaa agggaaauuu      180

gaagauaugg caaaagcgga caaggcaagg uacgagcgag aaaugaagac auauaucccg      240

ccaaagggcg agacaaagaa gaaauucaaa gacccgaacg cgcccaagcg cccgccaucg      300

gccuuuuucc uauucugcag cgaguacagg cccaagauaa agggcgagca cccaggauug      360

agcauaggcg augucgcgaa aaagcuaggg gaaaugugga acaacacggc cgcggacgau      420

aaacagccgu augaaaagaa agcggccaag cucaaggaaa aguacgagaa agauaucgcg      480

gccuauagag cgaaaggaaa accggacgcg gccaagaaag ggguagugaa agcggaaaag      540

agcaagaaaa agaaagagga agaggaagau gaagaggacg aggaagacga agaggaagag      600

gaagaugaag aggacgagga cgaggaagag gacgaugacg augaauag                   648


<210>  5299
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt8) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5299
augaacuucc uccucuccug gguccacugg acccucgccc uccuccucua ccuucaccac       60

gcaaaauggu cccaagccgc ccccaccacc gaaggagaac aaaaauccca cgaagucaua      120

aaauucaugg acguauacca acgaucauac ugccgaccca ucgaaacccu agucgacauc      180

uuccaagaau acccagacga aaucgaauac auauucaaac ccuccugcgu accccucaug      240

cgcugcgccg gcugcugcaa cgacgaagcc cuagaaugcg ucccaacauc agaaucaaac      300

aucaccaugc aaaucaugcg caucaaacca caccaauccc aacacauagg cgaaaugucc      360

uuccuccaac acucacgcug cgaaugccgc cccaaaaaag accgaaccaa acccgaaaaa      420

aaaucagucc gaggcaaagg aaaaggccaa aaacgcaagc gcaaaaaauc ccgcuucaaa      480

uccugguccg uccacugcga acccugcucc gaacgccgaa aacaccucuu cguccaagac      540

ccacaaaccu gcaaaugcuc cugcaaaaac accgacucca gaugcaaagc acgccaacuc      600

gaacucaacg aaagaaccug ccgcugcgac aaaccccgcc gcuaa                      645


<210>  5300
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt9) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5300
auggacuccg acgaaaccgg auucgaacac ucaggccucu gggucucagu ccucgccggc       60

cuccuccucg gagccugcca agcccaccca auccccgacu ccucaccacu ccuccaauuc      120

ggcggccaag uccgacaacg auaccucuac accgacgacg cccaacaaac cgaagcccac      180

cucgaaaucc gcgaagacgg cacaguagga ggcgccgccg accaaucacc cgaaucccua      240

cuccaacuaa aagcacucaa acccggcguc auccaaauac ucggcgucaa aaccucaaga      300

uuccucugcc aacgccccga cggcgcccuc uacggcuccc uccacuucga ccccgaagcc      360

ugcuccuucc gcgaacgccu ccucgaagac ggcuacaacg ucuaccaauc cgaagcccac      420

ggccuccccc uccaccuccc aggcaacaaa uccccacacc gcgaccccgc accccgcggc      480

ccagcccgcu uccucccccu ccccggacua cccccugccc uacccgaacc accaggcauc      540

cucgcacccc aaccacccga cgucggcucc uccgaccccc ucucaauggu aggcggcuca      600

caaggccgau cccccuccua cgaauccuaa                                       630


<210>  5301
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt9) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5301
augauguggg gcacaaaacu ccuuccggua cugcugcuac aacacgugcu ucuccaccuc       60

cuucuacucc acgucgcaau ccccuaugca gaagggcaga aaaagcgacg caacacacuc      120

cacgaguuca agaaaucggc caaaacaacc cuaaccaaag aggacccccu ccucaaaauc      180

aaaaccaaga aaguaaacuc cgccgacgag ugcgccaaca gaugcauccg caaccggggc      240

uucaccuuca caugcaaagc cuucguguuc gauaaaagcc gcaaacgaug cuacugguac      300

ccauucaacu ccaugagcuc gggaguuaag aaaggcuuug gccacgaauu ugaccuauac      360

gagaauaaag acuacauaag aaacugcauc aucgguaaag gcggcucaua caaagggacc      420

guauccauca caaaaagcgg aauaaaaugc caaccgugga acucuaugau accccacgaa      480

cacucauucc uaccauccuc auaccgcggc aaagaccuac aagagaacua cugccgaaac      540

ccccgaggag aagaaggggg accauggugc uucaccucaa acccagaggu acgguacgaa      600

gucugcgaca ucccacaaug cagcgaagua gagugcauga ccuguaacgg agaguccuac      660

cggggaccaa uggaccauac cgaaucggga aaaacuugcc aacgauggga ucaacaaaca      720

ccccaucguc acaaauuccu accggaacga uacccagaca aaggauucga cgacaacuac      780

ugcagaaauc ccgacgguaa acccagaccu uggugcuaca cccuagaccc cgacacccca      840

ugggaauacu gcgccauaaa gaccugcgca cacucugccg ucaacgagac cgacgucccc      900

auggaaacaa ccgaaugcau acaggggcag ggagagggcu accgcggcac cagcaacacc      960

aucuggaacg guauacccug ccagcgaugg gacagccaau acccccacaa gcacgacaua     1020

accccugaga acuucaagug caaagaccua cgcgaaaacu acugccgaaa cccagacggc     1080

gccgaaucac caugguguuu cacaacagac ccaaacaucc gcgucggcua cugcucccaa     1140

auacccaaau gcgacgucag uuccggacaa gacugcuacc gaggcaacgg aaagaacuac     1200

augggaaacc ucuccaaaac ccguagcggu uuaacaugcu ccauguggga caagaacaug     1260

gaagaccuac acagacauau auucugggaa cccgacgcaa gcaaacucaa caaaaauuac     1320

ugccgcaacc ccgacgacga ugcccauggc cccuggugcu acaccggcaa cccccugauc     1380

cccugggacu acuguccaau aagccgaugc gagggggaca ccaccccuac caucgucaac     1440

cuggaccacc ccgucaucuc cugcgcaaaa accaaacagc uccgaguagu gaacggcauc     1500

ccaacccaga caacggucgg auggaugguc ucacuaaaau accgaaacaa acacauaugc     1560

gguggauccc ucaucaaaga aagcuggguc uuaaccgccc gccaaugcuu ccccgcacga     1620

aacaaagacc uaaaagacua cgaagcaugg cuaggcaucc acgacguaca cgaacgaggc     1680

gaagaaaaac gaaagcaaau ccucaacauc ucacaguuag ucuacggacc agaagguuca     1740

gaccucgugc uccuaaaguu agcccgcccc gccauacuag acaacuucgu cagcaccauc     1800

gaccuaccau cauacggaug caccauacca gagaaaacca caugcaguau cuacggcugg     1860

ggcuacacgg gccucaucaa cgccgacggc cuccuacgcg uagcccaccu cuauaucaug     1920

ggcaacgaaa aaugcucaca acaccaccaa gggaaaguaa cacugaacga auccgagcuc     1980

ugcgccggcg ccgagaaaau cggauccggc cccugcgaag gagacuacgg gggaccacua     2040

auaugcgaac agcacaagau gcgaaugguc cucggaguca ucguacccgg ccgaggcugc     2100

gcaauaccca aucgccccgg cauauucguu cgcguagccu acuacgcuaa auggauccac     2160

aaagucauac ucaccuacaa acuauaa                                         2187


<210>  5302
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt9) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5302
auggggaaag gggacccgaa gaaaccaagg ggaaaaaugu cgagcuaugc cuucuucgug       60

caaacgugca gggaggaaca caagaaaaag cacccagacg cgagcgugaa cuuuagcgag      120

uucucgaaaa agugcucgga aagguggaag acaaugagcg cgaaagagaa agggaaauuu      180

gaagauaugg cgaaagcgga caaggccagg uacgagcgag agaugaagac cuauaucccg      240

cccaagggcg agacaaagaa gaaauucaaa gacccgaacg cgccaaagcg cccgcccucg      300

gcauuuuucu uguucuguag cgaguacagg ccaaagauca agggcgagca cccaggcuug      360

agcauaggcg augucgccaa aaagcucggg gaaaugugga auaacacagc agcagacgau      420

aaacagcccu augaaaagaa agcggcaaag cucaaggaaa aguacgagaa agauaucgcg      480

gccuaucgcg cgaaagggaa accggacgcg gcaaagaaag gggucgugaa agcggaaaag      540

agcaagaaaa agaaagagga agaggaagau gaagaggacg aggaagauga agaggaagag      600

gaagaugaag aggacgagga cgaagaagag gacgaugacg augaauag                   648


<210>  5303
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt9) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5303
augaacuucc uccucuccug gguccacugg acacucgccc uccuccuaua ccuacaccac       60

gccaaaugga gccaagccgc ccccacaacc gaaggcgaac aaaaauccca cgaagucauc      120

aaauucaugg acgucuacca acgcuccuac ugccgcccca ucgaaacccu cgucgacauc      180

uuccaagaau accccgacga aaucgaauac aucuucaaac ccuccugcgu cccccucaug      240

cgcugcgccg gcugcugcaa cgacgaagcc cucgaaugcg uccccaccuc agaaucaaac      300

auaacaaugc aaaucaugcg caucaaaccc caccaauccc aacacaucgg agaaaugucc      360

uuccuccaac acucacgcug cgaaugccgc ccaaaaaaag accgcaccaa acccgaaaaa      420

aaauccguac gcggcaaagg caaaggccaa aaacgcaaac gcaaaaaauc ccgcuucaaa      480

ucauggucag uccacugcga acccugcagc gaacgacgca aacaccucuu cguccaagac      540

ccacaaacau gcaaaugcuc cugcaaaaac acagacucgc gcugcaaagc ccgccaacuc      600

gaacuaaacg aacgcaccug ccgcugcgac aaaccccgac gcuag                      645


<210>  5304
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt11) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5304
auggacuccg acgaaaccgg cuucgaacac uccggccucu gggucuccgu ccucgccggc       60

cuccuccuag gcgcaugcca agcccacccc auacccgacu ccucaccccu ccuccaauuc      120

ggcggccaag uccgccaacg cuaccuauac accgacgacg cccaacaaac agaagcccac      180

cucgaaaucc gagaagacgg cacagucggc ggcgccgccg accaaagccc cgaaucccuc      240

cuccaacuca aagcccucaa acccggcguc auccaaaucc ucggcgucaa aacaucccgc      300

uuccuaugcc aacgccccga cggcgcccuc uacggcucac uccacuucga ccccgaagcc      360

ugcuccuucc gcgaacgccu ccucgaagac ggcuacaacg ucuaccaauc cgaagcccac      420

ggccuacccc uacaccuccc cggcaacaaa uccccucacc gcgaccccgc accccgcggc      480

cccgcccgcu uccuaccccu ccccggccuc ccccccgccc uacccgaacc ccccggcauc      540

cucgcccccc aacccccaga cgucggcucc ucugaccccc ucuccauggu cggcggcucc      600

caaggccgcu cacccuccua cgaauccuaa                                       630


<210>  5305
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt11) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5305
augauguggg gaacaaaauu acuaccaguc cuacuacucc aacacguccu acuccaccua       60

cuacuacucc acgucgcaau ccccuacgcc gaaggacaga aaaagcgaag aaacacacua      120

cacgaauuua agaaaucagc caaaaccacc cuaaccaaag aagacccccu acugaaaauc      180

aaaacuaaga aagucaacuc cgcagaugag ugcgcaaacc gaugcauacg caaccgcggc      240

uucacauuca cuugcaaagc cuucguuuuc gacaaaucac gaaaacgcug cuacugguac      300

cccuuuaacu cgaugagcuc aggcgugaag aaaggcuucg gccaugaguu cgaccuauac      360

gaaaauaaag auuacauacg uaacugcauc aucggaaaag guggcagcua caaaggcacu      420

gucucaauaa cgaaaagugg caucaaaugc caacccugga acuccaugau cccucacgaa      480

cacucauucc uccccuccag cuacagaggg aaagaccuac aagaaaacua cugccguaau      540

ccaagaggag aagaaggcgg accuuggugc uucaccucca accccgaagu aagauacgaa      600

gugugcgaca uaccacaaug cuccgaaguc gaaugcauga ccugcaacgg cgaauccuac      660

cgaggaccca uggaccacac cgaaucaggu aagaccugcc aacgcuggga ccaacaaaca      720

ccccacagac acaaauuccu cccugaacgc uaccccgaca aaggcuucga cgacaacuac      780

ugcaggaacc cagacgguaa accccgaccc ugguguuaca cccucgaccc agauacaccc      840

ugggaauacu gcgccauaaa aacaugcgca cacuccgccg ucaacgagac agacgucccc      900

auggaaacca ccgagugcau acaaggacaa ggggaaggau acagaggaac aucaaacacc      960

auuuggaacg gcauacccug ccaaagaugg gacucccagu auccccacaa acacgacauc     1020

acaccagaaa acuucaaaug caaggaccua cgagaaaacu acugccgcaa cccagacgga     1080

gcugaauccc ccuggugcuu cacaacagac ccgaauaucc gcgucggaua cuguucgcaa     1140

aucccaaagu gcgacgucag cucaggacaa gacugcuaca gaggaaacgg caagaacuau     1200

augggcaacc uuucgaaaac acgcagcggc cuaaccugcu ccauguggga caagaacaug     1260

gaagaccucc accggcacau auucugggaa cccgacgcaa guaaacuuaa caaaaacuac     1320

ugucgcaauc cggacgacga cgcccacggc ccuuggugcu acaccgguaa cccccuaauc     1380

ccgugggacu acugccccau aucccgaugc gaaggagaua caacacccac caucgugaac     1440

cuagaccacc ccgucaucuc augcgcuaaa acgaaacagc uccgagucgu caacggcauc     1500

ccaacgcaaa cgaccgucgg auggaugguc ucccugaaau accgcaacaa acacauaugc     1560

ggcggaagcc uaauaaaaga aagcuggguc cuuacagccc ggcaaugcuu cccagcccgu     1620

aacaaagacc ucaaagacua cgaagccugg cucggcaucc acgacguaca ugaacgaggg     1680

gaagaaaaac gcaaacaaau acucaacauc ucccagcugg uauacggccc ggaaggaagc     1740

gaccucgucc ucuugaaacu agccagaccc gccauacuag acaacuucgu cagcaccauc     1800

gaccuccccu cauacggcug caccauccca gaaaagacaa ccugcucaau cuacggcugg     1860

ggcuacaccg gacuaaucaa cgccgacgga cuccugcggg ucgcccauuu guacaucaug     1920

ggaaacgaaa aaugcuccca acaccaccaa ggcaaaguca cccugaacga auccgaacuc     1980

ugcgcaggcg ccgagaaaau cggaucagga cccugcgaag gggacuacgg gggcccccuc     2040

aucugcgagc aacauaaaau gcguauggug cuaggcguga ucguccccgg acgcggaugc     2100

gccaucccga accgccccgg gaucuucguc cgcgucgccu acuacgccaa auggauacau     2160

aaagucauuc ucaccuacaa gcuguaa                                         2187


<210>  5306
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt11) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5306
auggggaaag gggacccgaa aaagccgagg ggaaagaugu cgagcuaugc cuucuucgug       60

caaacgugca gggaggaaca caagaaaaag cacccggacg cgagcgugaa cuucagcgag      120

uucucgaaaa agugcucgga aagguggaag accaugagcg cgaaagagaa agggaaauuu      180

gaagauaugg cgaaagcgga caaggcaagg uacgagcgag agaugaagac auauauacca      240

ccaaagggcg agaccaagaa aaaguucaag gacccgaacg cgcccaagcg cccgccaucg      300

gccuuuuucu uguucuguag cgaguacagg cccaagauca agggagagca cccgggcuug      360

agcauaggcg acgucgcgaa aaagcucggg gaaaugugga auaacacggc cgcggacgau      420

aaacagccau augaaaagaa agcggccaag cuaaaggaaa aguacgagaa agauaucgcg      480

gcauaucgcg cgaaagggaa accggacgcg gccaagaaag gagucguaaa agcggaaaag      540

agcaagaaaa agaaagagga agaggaagau gaagaggacg aggaagauga agaggaagag      600

gaagaugaag aggacgagga cgaggaagag gacgaugacg augaauag                   648


<210>  5307
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt11) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5307
augaacuucc uccuauccug gguccacugg acacucgccc uccuccucua ccuccaccac       60

gccaaauggu cccaagcagc acccaccaca gaaggcgaac aaaaauccca cgaagucauc      120

aaguucaugg acgucuacca acgcucauac ugccgcccca ucgaaacacu cguagacauc      180

uuccaagaau accccgacga aaucgaauac aucuucaaac ccuccugcgu cccacuaaug      240

cgcugcgccg gaugcugcaa cgacgaagcc cucgaaugcg ucccaaccuc cgaauccaac      300

aucaccaugc aaaucaugcg caucaaaccc caccaauccc aacacaucgg cgaaaugucc      360

uuccuccaac acucccgcug cgaaugccgc cccaaaaaag accgcaccaa acccgaaaaa      420

aaaucagucc gcggcaaagg caaaggucaa aaacgaaaac gcaaaaaauc acgcuucaaa      480

uccugguccg uccacugcga acccugcuca gaacgacgca aacaccucuu cguccaagac      540

ccccaaaccu gcaaaugcuc augcaaaaac accgacuccc gaugcaaagc ccgccaacuc      600

gaacucaacg aacgaaccug ccgcugcgac aaaccccgac gcuaa                      645


<210>  5308
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt12) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5308
auggacucug acgaaacagg uuucgaacac ucaggacuau gggucucagu auuagcagga       60

cuauuauuag gagcauguca agcacaucca auaccagacu caucaccacu acuacaauuc      120

ggcggacaag uaagacaaag auacuuauac acagacgaug cacaacaaac agaagcacau      180

uuagaaauaa gagaagaugg cacaguaggc ggagcagcag accaaucacc agaaucacua      240

uuacaauuaa aagcauuaaa accaggagua auacaaauau uaggaguaaa aacaucaaga      300

uucuuauguc aaagaccuga cggagcacua uacggaucac uacacuuuga cccagaagca      360

ugcucauuua gagaaagauu auuagaagac ggauacaaug uauaucaauc agaagcacac      420

ggauuaccau uacacuuacc cggaaauaaa ucaccacaua gagacccagc accaagagga      480

ccugcaagau uucuaccucu accaggacua ccaccagcac uaccugaacc accaggaaua      540

uuagcaccac aaccaccaga cguaggaucc ucagaccccu uaucaauggu aggcggauca      600

caaggaagau caccaucaua ugaaucauaa                                       630


<210>  5309
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt12) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5309
augauguggg gaacuaaauu acuaccaguu cuauuacuuc aacacguccu auuacauuua       60

uuacuauuac acguugcaau accauaugca gaaggacaaa aaaaaagaag gaacaccuua      120

cacgaauuua aaaaaucggc aaaaacaacc cucacaaagg aagacccacu auuaaaaauc      180

aaaacaaaaa aagugaauag ugcagacgaa ugugcaaaua gaugcauaag aaacagagga      240

uuuacauuca cuuguaaagc auuuguauuu gauaaaucaa ggaaaaggug uuauugguau      300

ccuuuuaacu caaugucuag uggaguaaaa aaaggauucg gacaugaauu ugaccuauau      360

gaaaauaaag acuauauaag aaauugcaua auaggaaaag guggaucaua uaaagggaca      420

guuagcauaa ccaaaucagg cauaaaaugu caaccaugga auucaaugau accacaugaa      480

cauuccuuuc uaccuaguag uuaucgugga aaagauuuac aagaaaauua uuguagaaac      540

ccaagaggag aagaaggagg gccauggugc uuuacaagca acccagaagu cagauaugaa      600

guaugugaca uaccacaaug uucagaagua gaauguauga caugcaaugg agaaucguau      660

agagguccaa uggaccauac agaaucagga aaaacauguc aaagauggga ucaacaaacc      720

ccacaucgac auaaauucuu accagaacga uauccagaca aaggguucga cgauaauuau      780

ugcagaaauc cagaugggaa accaagaccc ugguguuaca cucuagaccc cgauacacca      840

ugggaauauu gugcaauaaa aacaugcgca cacucagcag uaaaugagac ugauguccca      900

auggaaacua cagaaugcau ucaaggacaa ggugaagguu accgaggcac aaguaauacu      960

auauggaaug ggauaccaug ucaaagaugg gacagucaau acccacauaa acaugauaua     1020

acgccagaaa auuuuaaaug uaaagauuua agagaaaauu auugcagaaa uccugauggc     1080

gcggaaaguc cauggugcuu cacaacugau ccuaacauaa gaguugguua uugcagucaa     1140

auaccuaaau gcgauguauc auccggacaa gauuguuaua gggguaaugg aaaaaauuau     1200

augggcaauu uaucaaaaac acguagugga uuaacauguu caauguggga uaaaaauaug     1260

gaagauuuac aucgacacau uuucugggaa cccgaugcua guaaauuaaa caaaaacuau     1320

ugucgaaacc cagaugauga ugcacaugga ccauggugcu auacagguaa cccacuuaua     1380

ccaugggacu auuguccuau aucaagaugu gaaggcgaua caacaccuac uauagucaau     1440

uuagaucauc cuguaaucag uugcgcuaaa acaaaacaau uaagaguugu aaacggaauu     1500

ccaacacaaa caacaguagg auggauggua ucacucaaau accgaaauaa acacauaugc     1560

ggagguucuu uaauaaaaga aagcugggua uuaaccgcaa gacaaugcuu cccggcaaga     1620

aauaaagauu uaaaagauua ugaagcaugg uuaggaauac acgauguaca cgaaagggga     1680

gaagaaaaaa gaaaacaaau acuaaauaua ucacaauuag uauacggccc agaagggagc     1740

gaucuaguuc uucuaaaauu agccagacca gcaauauuag auaauuuugu aucuacuauc     1800

gaucuaccau cauauggaug uacaauaccu gagaaaacaa cauguucaau auauggaugg     1860

ggauauacug gauuaauaaa cgccgaugga cuucuuagag uagcacacuu auauauaaug     1920

ggaaacgaaa aaugcucaca acaucaucaa ggaaaaguua cacuaaacga aucagaacua     1980

ugugcuggcg cagaaaaaau cggaucaggc ccaugcgaag gugauuacgg cggaccacuu     2040

auaugugaac aacauaaaau gcgcauggua uuaggaguca uaguucccgg ucggggcugu     2100

gcgauaccaa acagaccagg cauauuuguc cguguagccu acuaugcaaa auggauacau     2160

aaaguaauau uaacauauaa auuauaa                                         2187


<210>  5310
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt12) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5310
augggaaaag gagacccaaa aaaaccaaga ggaaaaaugu caagcuacgc auucuucgua       60

caaacaugca gagaagaaca caaaaaaaaa cacccagacg caagcguaaa cuucagcgaa      120

uucagcaaaa aaugcucaga aagguggaaa acaaugagcg caaaagagaa aggaaaauuc      180

gaagacaugg caaaagcaga caaagcaaga uacgaaagag aaaugaaaac auacauacca      240

ccaaaaggag aaacaaaaaa aaaauuuaaa gacccaaacg caccaaaaag accaccauca      300

gcauucuucc uauucugcag ugaauacaga ccaaaaauaa aaggagaaca cccaggacua      360

agcauaggag acguagcaaa aaaauuagga gaaaugugga acaacacagc agcagacgac      420

aaacaaccau acgaaaaaaa agcagcaaaa uuaaaagaaa aauacgaaaa ggacauagca      480

gcauaucgag caaaaggaaa accagacgca gcaaaaaaag gaguaguaaa agcagaaaaa      540

agcaaaaaaa aaaaagaaga agaagaagac gaagaagacg aagaagacga agaagaagaa      600

gaagacgaag aagacgaaga cgaagaagaa gacgacgacg acgaauaa                   648


<210>  5311
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt12) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5311
augaacuucc uacuaucaug gguacacugg acacuagcau uacuacuaua cuuacaccac       60

gcaaaauggu cacaagcagc accaacaaca gaaggagaac aaaaaucaca cgaaguaaua      120

aaauucaugg acguauacca acgaucauac ugcagaccaa uagaaacacu aguagacaua      180

uuccaagaau acccagacga aauagaauac auauucaaac caucaugcgu accauuaaug      240

agaugcgcag gaugcugcaa cgacgaagca uuagaaugcg uaccaacauc agaaucaaac      300

auaacaaugc aaauaaugag aauaaaacca caccaaucac aacacauagg agaaauguca      360

uuccuacaac auucaagaug cgaaugcaga ccaaaaaaag acagaacaaa accagaaaaa      420

aaaucaguaa gaggaaaagg aaaaggacaa aaaagaaaaa gaaaaaaauc aagauucaaa      480

ucauggucag uacacugcga accaugcuca gaacgaagaa aacacuuauu uguacaagac      540

ccacaaacau gcaaaugcuc augcaaaaac acagacucaa gaugcaaagc aagacaacua      600

gaacuaaaug aaagaacaug cagaugugac aaaccaagac gauaa                      645


<210>  5312
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt13) from Homo 
       sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E)

<400>  5312
auggacucag acgaaacagg auuugaacac ucaggacuau ggguaucagu acuagcagga       60

uuauuacuag gagccugcca agcacaccca auaccagacu caucaccauu auuacaauuc      120

ggaggacaag uuagacaaag auaucuauau acagaugacg cacaacaaac agaagcacac      180

uuagaaauaa gagaagacgg aacaguagga ggagcagcag accaaucacc agaaucccua      240

cuacaauuaa aagcacuaaa accaggagua auacaaauau uaggaguaaa aacaucaaga      300

uuccuaugcc aaagaccaga cggagcacua uacggcucac uacacuuuga cccagaagca      360

ugcucauuca gagaaagacu acuagaagac ggauauaaug uauaucaauc agaagcacac      420

ggacuaccuu uacauuuacc aggaaacaaa ucaccacaca gagacccagc accaagaggc      480

ccagcacgcu uuuuaccauu accaggacua ccaccagcau uaccagaacc accaggaaua      540

cuagcaccac aaccaccaga uguuggaagc ucagacccac uaucaauggu aggaggauca      600

caaggaagau caccaucaua ugaaucauaa                                       630


<210>  5313
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt13) from Mus 
       musculus__NP_001276387.1__MmHGF

<400>  5313
augauguggg gaacaaaacu uuuaccuguu cuauuauuac aacacguccu guuacacuua       60

uuauuacuac auguagccau accuuacgca gaaggacaaa agaaacgaag aaacacacuu      120

caugaauuua agaaauccgc aaaaacaaca uuaacaaaag aagauccauu auuaaaaaua      180

aaaacaaaga aaguuaauuc agcagaugaa ugugcaaaua gauguauaag aaacagagga      240

uuuaccuuua cauguaaagc auuuguauuc gacaaaucaa ggaaacgaug uuacugguau      300

ccauucaaua guaugaguuc uggaguaaag aaaggauucg gucaugaguu cgaccuauau      360

gaaaauaaag acuauauuag aaauuguaua aucggcaaag gugggucuua uaaaggcacu      420

guuaguauaa caaaaucagg aauaaaaugu caaccaugga auagcaugau accacacgaa      480

cacucauuuc ucccaucuuc auacaggggc aaagaccuac aagaaaauua uuguagaaac      540

ccaaggggag aagaaggagg cccauggugu uuuacaucga auccugaagu acgauaugaa      600

guaugugaca ucccccaaug cagugaagua gaauguauga cuuguaaugg ugaaucauac      660

cgaggaccua uggaccauac agaaucagga aaaacuugcc aacgauggga ucaacaaacc      720

ccucaucgac acaaauuuuu accagaacgu uacccagaua aaggauuuga cgauaauuac      780

uguagaaauc cagacgguaa accucgaccc ugguguuaca cucuugaucc agauacacca      840

ugggaauauu gcgcaauaaa aacuugcgca cauucugcag uaaaugaaac agacguucca      900

auggaaacua ccgaauguau acaaggccaa ggagaaggcu auagagguac aucaaauaca      960

auauggaaug gcauacccug ccaaaggugg gacucucaau auccacauaa acaugauaua     1020

acaccagaaa acuuuaaaug uaaagauuua agagaaaauu acuguagaaa uccggaugga     1080

gcagaaucuc ccugguguuu cacuaccgau ccuaacauaa gaguaggaua uuguagccaa     1140

auaccuaaau gugauguuag cucaggucaa gacugcuaca gagguaaugg caaaaauuac     1200

auggggaauc ucaguaaaac acguagugga cucacauguu caauguggga uaaaaauaug     1260

gaagaccugc acagacauau auucugggaa ccugaugcuu caaaauuaaa uaaaaauuau     1320

ugcagaaauc cagaugauga cgcucacgga ccaugguguu acacugguaa uccauuaaua     1380

ccaugggauu auuguccaau aucaagaugc gaaggugaua caacuccaac aauaguaaau     1440

cuagaucauc caguaauauc cugugcaaaa acaaaacaac uaagaguagu aaacggaaua     1500

ccaacacaaa caacaguagg auggaugguu aguuuaaaau acagaaauaa acauauaugu     1560

ggaggauccu uaauaaaaga aucaugggua uuaacugcaa gacaauguuu cccagcaagg     1620

aacaaagauu uaaaagauua cgaagcaugg cuaggaauac augauguuca cgaaagagga     1680

gaagaaaaac guaaacaaau uuugaacauu ucacaacuug uauacggccc agaaggaucu     1740

gauuuaguau uauuaaaguu agcaagacca gcaauucucg auaauuucgu aucaacgaua     1800

gaucucccca guuacggcug uacgauacca gaaaagacaa caugcaguau auacggaugg     1860

ggauauacag gacuaaucaa cgcagaugga cuuuuaagag uagcccacuu auauauaaug     1920

gguaacgaaa aauguucaca acaucaucaa ggaaaaguaa cacuaaauga aagcgaauua     1980

ugugcaggcg cagagaaaau aggaagcgga ccuugugaag gcgauuacgg uggaccacua     2040

auaugugaac aacauaaaau gagaauggua uuaggaguaa uaguuccagg acguggaugu     2100

gccauaccaa accgaccagg aauauuuguu aggguagccu acuacgcaaa auggauucac     2160

aaaguaauau uaacauauaa acuauaa                                         2187


<210>  5314
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt13) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5314
augggaaaag gagacccaaa aaaaccgaga ggaaaaauga gcagcuacgc auuuuucgua       60

caaacaugca gagaagaaca caaaaaaaaa cacccagacg caagcguaaa cuuuagcgaa      120

uuuucaaaaa aaugcucaga aagauggaaa acaaugagcg caaaagaaaa aggaaaauuc      180

gaagacaugg cgaaagcaga caaagcaaga uaugaaagag aaaugaaaac auacauacca      240

ccaaaaggag aaaccaaaaa aaaauuuaaa gacccaaacg caccaaaaag accaccaagc      300

gcauucuuuc uauucugcag ugaauacaga ccaaaaauaa aaggagaaca cccaggauua      360

agcauaggag acguagcaaa aaaacuagga gaaaugugga acaacacagc agcagacgac      420

aaacaaccau acgaaaaaaa agcagcaaaa cuaaaagaaa aauacgaaaa agacauagca      480

gcauauagag caaaaggaaa accagacgca gcaaaaaaag gaguaguaaa agcagaaaaa      540

agcaaaaaaa aaaaagaaga agaagaagac gaagaagacg aagaagacga agaagaagaa      600

gaagacgaag aagacgaaga cgaagaagaa gacgacgacg acgaauaa                   648


<210>  5315
<211>  645
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt13) from Mus 
       musculus__NP_001273985.1__MmVEGFA

<400>  5315
augaacuucc uacuaucaug gguacacugg acacuagcac uacuacuaua cuuacaccac       60

gcaaaaugga gucaagcagc accaacaaca gaaggagaac aaaaaagcca cgaaguaaua      120

aaauucaugg acguauauca acgaucauac ugcagaccaa uagaaacacu aguagauauc      180

uuccaagaau acccagacga aauagaauac auauucaaac caucaugcgu accauuaaug      240

agaugcgcag gaugcugcaa cgacgaagca cuagaaugcg uaccaacauc agaaucaaac      300

auaacaaugc aaauaaugag aauaaaaccc caccaaagcc aacacauagg agaaauguca      360

uuccuacaac acucaagaug cgaaugcaga cccaaaaaag accgaacaaa accagaaaaa      420

aaaucaguaa gaggaaaagg aaaaggacaa aaaagaaaac gaaaaaaauc acgauucaaa      480

ucauggucag uacacugcga accaugcucu gaaagaagaa aacaccuauu cguacaagac      540

ccacaaacau guaaaugcag cugcaaaaac acagacucaa gaugcaaagc aagacaacua      600

gaauuaaacg aaagaacaug cagaugcgac aaaccacgaa gauaa                      645


<210>  5316
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (wt)

<400>  5316
gggagaaagc uuaccaugga cucggacgag accggguucg agcacucagg acuguggguu       60

ucugugcugg cuggucuucu gcugggagcc ugccaggcac accccauccc ugacuccagu      120

ccucuccugc aauucggggg ccaaguccgg cagcgguacc ucuacacaga ugaugcccag      180

cagacagaag cccaccugga gaucagggag gaugggacgg uggggggcgc ugcugaccag      240

agccccgaaa gucuccugca gcugaaagcc uugaagccgg gaguuauuca aaucuuggga      300

gucaagacau ccagguuccu gugccagcgg ccagaugggg cccuguaugg aucgcuccac      360

uuugacccug aggccugcag cuuccgggag cggcuucuug aggacggaua caauguuuac      420

caguccgaag cccacggccu cccgcugcac cugccaggga acaagucccc acaccgggac      480

ccugcacccc gaggaccagc ucgcuuccug ccacuaccag gccugccccc cgcacucccg      540

gagccacccg gaauccuggc cccccagccc cccgaugugg gcuccucgga cccucugagc      600

auggugggag guucccaggg ccgaagcccc agcuacgagu ccugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5317
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (wt)

<400>  5317
gggagaaagc uuaccaugga cucggacgag accggguucg agcacucagg acuguggguu       60

ucugugcugg cuggucuucu gcugggagcc ugccaggcac accccauccc ugacuccagu      120

ccucuccugc aauucggggg ccaaguccgg cagcgguacc ucuacacaga ugaugcccag      180

cagacagaag cccaccugga gaucagggag gaugggacgg uggggggcgc ugcugaccag      240

agccccgaaa gucuccugca gcugaaagcc uugaagccgg gaguuauuca aaucuuggga      300

gucaagacau ccagguuccu gugccagcgg ccagaugggg cccuguaugg aucgcuccac      360

uuugacccug aggccugcag cuuccgggag cggcuucuug aggacggaua caauguuuac      420

caguccgaag cccacggccu cccgcugcac cucccaggga acaagucccc acaccgggac      480

ccugcacccc gaggaccagc ucgcuuccug ccacuaccag gccugccccc cgcacucccg      540

gagccacccg gaauccuggc cccccagccc cccgaugugg gcuccucgga cccucugagc      600

auggugggag guucccaggg ccgaagcccc agcuacgagu ccugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5318
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (wt)

<400>  5318
gggagaaagc uuaccaugau gugggggacc aaacuucugc cgguccuguu gcugcagcau       60

guccuccugc accuccuccu gcuucauguc gccauccccu augcagaagg acagaagaaa      120

agaagaaaua cacuucauga auuuaaaaag ucagcaaaaa cuacucuuac caaggaagac      180

ccauuacuga agauuaaaac caaaaaagug aacucugcag augagugugc caacaggugu      240

aucaggaaca ggggcuuuac guucacuugc aaggccuucg uuuuugauaa gucaagaaaa      300

cgaugcuacu gguauccuuu caauaguaug ucaaguggag ugaaaaaagg guuuggccau      360

gaauuugacc ucuaugaaaa caaagacuau auuagaaacu gcaucauugg uaaaggaggc      420

agcuauaaag ggacgguauc caucacuaag aguggcauca aaugccagcc uuggaauucc      480

augauccccc augaacacag cuuuuugccu ucgagcuauc gcgguaaaga ccuacaggaa      540

aacuacuguc gaaauccucg aggggaagaa gggggacccu gguguuucac aagcaaucca      600

gagguacgcu acgaagucug ugacauuccu caguguucag aaguugaaug caugaccugc      660

aauggugaaa gcuacagagg ucccauggau cacacagaau caggcaagac uugucagcgc      720

ugggaccagc agacaccaca ccggcacaag uucuugccag aaagauaucc cgacaagggc      780

uuugaugaua auuauugccg caauccugau ggcaagccga ggccauggug cuacacucuu      840

gacccugaca ccccuuggga guauugugca auuaaaacgu gcgcucacag ugcugugaau      900

gagacugaug ucccuaugga aacaacugaa ugcauucaag gccaaggaga agguuacagg      960

ggaaccagca auaccauuug gaauggaauu cccugucagc guugggauuc gcaguacccu     1020

cacaagcaug auaucacucc cgagaacuuc aaaugcaagg accuuagaga aaauuauugc     1080

cgcaauccag auggggcuga aucaccaugg uguuuuacca cugacccaaa cauccgaguu     1140

ggcuacugcu cucaaauucc caagugugac gugucaagug gacaagauug uuaucguggc     1200

aaugggaaaa auuacauggg caacuuaucc aaaacaaggu cuggacuuac auguuccaug     1260

ugggacaaga auauggagga uuuacaccgu cauaucuucu gggagccaga ugcuagcaaa     1320

uugaauaaga auuacugccg gaauccugau gaugaugccc auggaccuug gugcuacacg     1380

gggaauccuc uuauuccuug ggauuauugc ccuauuuccc guugugaagg agauacuaca     1440

ccuacaauug ucaauuugga ccauccugua auauccugug ccaaaacaaa acaacugcgg     1500

guuguaaaug gcauuccaac acaaacaaca guagggugga ugguuaguuu gaaauacaga     1560

aauaaacaua ucuguggagg aucauugaua aaggaaaguu ggguucuuac ugcaagacaa     1620

uguuuuccag ccagaaacaa agacuugaaa gacuaugaag cuuggcuugg cauccacgau     1680

guucaugaga gaggcgagga gaagcgcaag cagaucuuaa acauuuccca gcuggucuau     1740

gguccugaag gcucagacuu gguuuuacug aagcuugcuc gaccugcaau ccuggauaac     1800

uuugucagua caauugauuu accuaguuau gguuguacaa ucccugaaaa gaccacuugc     1860

aguauuuacg gcuggggcua cacuggauug aucaacgcgg augguuuauu acgaguagcu     1920

caucuguaua uuauggggaa ugagaaaugc agucagcacc aucaaggcaa ggugacuuug     1980

aaugagucug aguuaugugc uggggcugaa aagauuggau caggaccaug ugagggagau     2040

uaugguggcc cacucauuug ugaacaacac aaaaugagaa ugguucuugg ugucauuguu     2100

ccuggucgug gaugugccau cccaaaucgu ccugguauuu uuguucgagu agcauauuau     2160

gcaaaaugga uacacaaagu aauuuugaca uacaaguugu aaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5319
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (wt)

<400>  5319
gggagaaagc uuaccaugau gugggggacc aaacuucugc cgguccuguu gcugcagcau       60

guccuccugc accuccuccu gcuucauguc gccauccccu augcagaagg acagaagaaa      120

agaagaaaua cacuucauga auuuaaaaag ucagcaaaaa cuacucuuac caaggaagac      180

ccauuacuga agauuaaaac caaaaaagug aacucugcag augagugugc caacaggugu      240

aucaggaaca ggggcuuuac guucacuugc aaggccuucg uuuuugauaa gucaagaaaa      300

cgaugcuacu gguauccuuu caauaguaug ucaaguggag ugaaaaaagg guuuggccau      360

gaauuugacc ucuaugaaaa caaagacuau auuagaaacu gcaucauugg uaaaggaggc      420

agcuauaaag ggacgguauc caucacuaag aguggcauca aaugccagcc uuggaacucc      480

augauccccc augaacacag cuuuuugccu ucgagcuauc gcgguaaaga ccuacaggaa      540

aacuacuguc gaaauccucg aggggaagaa gggggacccu gguguuucac aagcaaucca      600

gagguacgcu acgaagucug ugacauuccu caguguucag aaguugaaug caugaccugc      660

aauggugaaa gcuacagagg ucccauggau cacacagaau caggcaagac uugucagcgc      720

ugggaccagc agacaccaca ccggcacaag uucuugccag aaagauaucc cgacaagggc      780

uuugaugaua auuauugccg caauccugau ggcaagccga ggccauggug cuacacucuu      840

gacccugaca ccccuuggga guauugugca auuaaaacgu gcgcucacag ugcugugaau      900

gagacugaug ucccuaugga aacaacugaa ugcauucaag gccaaggaga agguuacagg      960

ggaaccagca auaccauuug gaauggaauc cccugucagc guugggauuc gcaguacccu     1020

cacaagcaug auaucacucc cgagaacuuc aaaugcaagg accuuagaga aaauuauugc     1080

cgcaauccag auggggcuga aucaccaugg uguuuuacca cugacccaaa cauccgaguu     1140

ggcuacugcu cucaaauucc caagugugac gugucaagug gacaagauug uuaucguggc     1200

aaugggaaaa auuacauggg caacuuaucc aaaacaaggu cuggacuuac auguuccaug     1260

ugggacaaga auauggagga uuuacaccgu cauaucuucu gggagccaga ugcuagcaaa     1320

uugaauaaga auuacugccg gaauccugau gaugaugccc auggaccuug gugcuacacg     1380

gggaauccuc uuauuccuug ggauuauugc ccuauuuccc guugugaagg agauacuaca     1440

ccuacaauug ucaauuugga ccauccugua auauccugug ccaaaacaaa acaacugcgg     1500

guuguaaaug gcauuccaac acaaacaaca guagggugga ugguuaguuu gaaauacaga     1560

aauaaacaua ucuguggagg aucauugaua aaggaaaguu ggguucuuac ugcaagacaa     1620

uguuuuccag ccagaaacaa agacuugaaa gacuaugaag cauggcuugg cauccacgau     1680

guucaugaga gaggcgagga gaagcgcaag cagaucuuaa acauuuccca gcuggucuau     1740

gguccugaag gcucagacuu gguuuuacug aagcuggcuc gaccugcaau ccuggauaac     1800

uuugucagua caauugauuu accuaguuau gguuguacaa ucccugaaaa gaccacuugc     1860

aguauuuacg gcuggggcua cacuggauug aucaacgcgg augguuuauu acgaguagcu     1920

caucuguaua uuauggggaa ugagaaaugc agucagcacc aucaaggcaa ggugacuuug     1980

aaugagucug aguuaugugc uggggcugaa aagauuggau caggaccaug ugagggagau     2040

uaugguggcc cacucauuug ugaacaacac aaaaugagaa ugguucuugg ugucauuguu     2100

ccuggucgug gaugugccau cccaaaucgu ccugguauuu uuguucgagu agcauauuau     2160

gcaaaaugga uacacaaagu aauuuugaca uacaaguugu aaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5320
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (wt)

<400>  5320
gggagaaagc uuaccauggg caaaggagau ccuaagaagc cgagaggcaa aaugucauca       60

uaugcauuuu uugugcaaac uugucgggag gagcauaaga agaagcaccc agaugcuuca      120

gucaacuucu cagaguuuuc uaagaagugc ucagagaggu ggaagaccau gucugcuaaa      180

gagaaaggaa aauuugaaga uauggcaaaa gcggacaagg cccguuauga aagagaaaug      240

aaaaccuaua ucccucccaa aggggagaca aaaaagaagu ucaaggaucc caaugcaccc      300

aagaggccuc cuucggccuu cuuccucuuc ugcucugagu aucgcccaaa aaucaaagga      360

gaacauccug gccuguccau uggugauguu gcgaagaaac ugggagagau guggaauaac      420

acugcugcag augacaagca gccuuaugaa aagaaggcug cgaagcugaa ggaaaaauac      480

gaaaaggaua uugcugcaua ucgagcuaaa ggaaagccug augcagcaaa aaagggaguu      540

gucaaggcug aaaaaagcaa gaaaaagaag gaagaggagg aagaugagga agaugaagag      600

gaugaggagg aggaggaaga ugaagaagau gaagaugaag aagaagauga ugaugaugaa      660

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5321
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (wt)

<400>  5321
gggagaaagc uuaccaugaa cuuucugcuc ucuugggugc acuggacccu ggcuuuacug       60

cuguaccucc accaugccaa guggucccag gcugcaccca cgacagaagg agagcagaag      120

ucccaugaag ugaucaaguu cauggauguc uaccagcgaa gcuacugccg uccgauugag      180

acccuggugg acaucuucca ggaguacccc gacgagauag aguacaucuu caagccgucc      240

ugugugccgc ugaugcgcug ugcaggcugc uguaacgaug aagcccugga gugcgugccc      300

acgucagaga gcaacaucac caugcagauc augcggauca aaccucacca aagccagcac      360

auaggagaga ugagcuuccu acagcacagc agaugugaau gcagaccaaa gaaagacaga      420

acaaagccag aaaaaaaauc aguucgagga aagggaaagg gucaaaaacg aaagcgcaag      480

aaaucccggu uuaaauccug gagcguucac ugugagccuu guucagagcg gagaaagcau      540

uuguuugucc aagauccgca gacguguaaa uguuccugca aaaacacaga cucgcguugc      600

aaggcgaggc agcuugaguu aaacgaacgu acuugcagau gugacaagcc aaggcgguga      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5322
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt1)

<400>  5322
gggagaaagc uuaccaugga cagcgacgag accggcuucg agcacuccgg gcugugggug       60

agcguccucg ccggccugcu gcucggggcc ugccaggccc accccauccc ggacuccagc      120

ccccugcugc aguucggcgg ccaggugcgc cagcgguacc ucuacaccga cgacgcccag      180

cagacggagg cccaccugga gauccgcgag gacgggaccg ugggcggggc cgccgaccag      240

ucccccgaga gccugcucca gcugaaggcg cugaagcccg gcgucaucca gauccucggg      300

gugaagaccu cccgguuccu gugccagcgc ccggacggcg cccuguacgg gagccuccac      360

uucgaccccg aggccugcuc cuuccgggag cgccugcucg aggacggcua caacguguac      420

cagagcgagg cccacggccu gccccugcac cuccccggga acaagucccc gcaccgcgac      480

cccgcgcccc ggggccccgc ccgcuuccug ccgcugcccg ggcucccgcc cgcccugccc      540

gagccgcccg gcauccuggc gccccagccg cccgacgucg gcagcuccga cccccucagc      600

augguggggg gcucccaggg ccggagcccc uccuacgaga gcugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5323
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt1)

<400>  5323
gggagaaagc uuaccaugau guggggcacc aagcugcucc ccgugcugcu gcuccagcac       60

guccugcugc accuccugcu gcuccacgug gccaucccgu acgccgaggg gcagaagaag      120

cgccggaaca cccugcacga guucaagaag agcgcgaaga cgacccugac caaggaggac      180

ccccuccuga agaucaagac caagaaggug aacuccgccg acgagugcgc caaccgcugc      240

auccggaacc gcggcuucac guucaccugc aaggccuucg ucuucgacaa gagccggaag      300

cgcugcuacu gguaccccuu caacuccaug agcuccgggg ugaagaaggg cuucgggcac      360

gaguucgacc uguacgagaa caaggacuac auccggaacu gcaucaucgg caagggcggg      420

agcuacaagg gcaccguguc caucaccaag agcgggauca agugccagcc cuggaacucc      480

augaucccgc acgagcacag cuuccucccc uccagcuacc gcggcaagga ccugcaggag      540

aacuacugcc ggaacccccg cggggaggag ggcggccccu ggugcuucac guccaacccg      600

gagguccggu acgaggugug cgacaucccc cagugcagcg agguggagug caugaccugc      660

aacggggagu ccuaccgcgg ccccauggac cacaccgaga gcgggaagac cugccagcgg      720

ugggaccagc agacgcccca ccgccacaag uuccugccgg agcgguaccc cgacaagggc      780

uucgacgaca acuacugccg caaccccgac ggcaagcccc ggccguggug cuacacccuc      840

gaccccgaca cccccuggga guacugcgcc aucaagaccu gcgcgcacuc cgccgucaac      900

gagacggacg ugcccaugga gaccaccgag ugcauccagg ggcagggcga gggguaccgc      960

ggcaccagca acacgaucug gaacgggauc ccgugccagc ggugggacuc ccaguacccc     1020

cacaagcacg acaucacccc cgagaacuuc aagugcaagg accugcgcga gaacuacugc     1080

cggaaccccg acggcgccga gagcccgugg ugcuucacca ccgaccccaa cauccgcgug     1140

ggcuacugca gccagauccc caagugcgac gucuccagcg ggcaggacug cuaccgcggc     1200

aacgggaaga acuacauggg caaccugucc aagacgcgga gcgggcucac cugcuccaug     1260

ugggacaaga acauggagga ccugcaccgc cacaucuucu gggagcccga cgccagcaag     1320

cugaacaaga acuacugccg gaacccggac gacgacgcgc acggccccug gugcuacacc     1380

ggcaaccccc ucaucccgug ggacuacugc cccaucuccc gcugcgaggg ggacaccacg     1440

cccaccaucg ugaaccugga ccaccccgug aucagcugcg ccaagaccaa gcagcugcgg     1500

gucgugaacg gcaucccgac ccagacgacc guggggugga uggucucccu caaguaccgc     1560

aacaagcaca ucugcggcgg gagccugauc aaggaguccu gggugcugac cgcccggcag     1620

ugcuuccccg cccgcaacaa ggaccucaag gacuacgagg ccuggcuggg cauccacgac     1680

gugcacgagc ggggcgagga gaagcgcaag cagauccuga acaucagcca gcucgucuac     1740

gggcccgagg gcuccgaccu ggugcugcuc aagcuggcgc ggcccgccau ccuggacaac     1800

uucgugagca ccaucgaccu cccguccuac gggugcacga uccccgagaa gaccaccugc     1860

agcaucuacg gcuggggcua caccgggcug aucaacgccg acggccugcu ccgcgucgcc     1920

caccuguaca ucauggggaa cgagaagugc ucccagcacc accagggcaa ggugacccug     1980

aacgagagcg agcucugcgc cggggcggag aagaucggcu ccggccccug cgagggggac     2040

uacggcgggc cccugaucug cgagcagcac aagaugcgga ugguccuggg cgugaucgug     2100

ccggggcgcg gcugcgccau ccccaaccgg cccggcaucu ucguccgcgu ggccuacuac     2160

gccaagugga uccacaaggu gauccugacg uacaagcucu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5324
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt1)

<400>  5324
gggagaaagc uuaccauggg caagggggac cccaagaagc cgcgcggcaa gaugagcagc       60

uacgccuucu ucgugcagac cugccgggag gagcacaaga agaagcaccc cgacgccagc      120

gucaacuucu ccgaguucag caagaagugc uccgagcgcu ggaagaccau gagcgcgaag      180

gagaagggga aguucgagga cauggccaag gccgacaagg cccgguacga gcgcgagaug      240

aagacguaca ucccgcccaa gggcgagacc aagaagaagu ucaaggaccc caacgccccc      300

aagcggccgc ccuccgcguu cuuccuguuc ugcagcgagu accgccccaa gaucaagggg      360

gagcaccccg gccucuccau cggcgacgug gccaagaagc ugggggagau guggaacaac      420

accgccgccg acgacaagca gcccuacgag aagaaggcgg ccaagcugaa ggagaaguac      480

gagaaggaca ucgccgccua ccgggccaag ggcaagcccg acgcggccaa gaagggggug      540

gucaaggccg agaaguccaa gaagaagaag gaggaggagg aggacgagga ggacgaggag      600

gacgaggagg aggaggagga cgaggaggac gaggacgagg aggaggacga cgacgacgag      660

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5325
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt1) R2139/R2140

<400>  5325
gggagaaagc uuaccaugaa cuuccugcuc agcugggugc acuggacccu ggcccugcuc       60

cuguaccugc accacgcgaa guggucgcag gccgccccga cgaccgaggg cgagcagaag      120

agccacgagg ucaucaaguu cauggacgug uaccagcgga gcuacugccg ccccaucgag      180

acccucgugg acaucuucca ggaguacccg gacgagaucg aguacaucuu caagccgucg      240

ugcguccccc ugaugcggug cgcggggugc ugcaacgacg aggcccugga gugcgugccg      300

acgagcgaga gcaacaucac caugcagauc augcggauca agccgcacca gucgcagcac      360

aucggcgaga ugagcuuccu ccagcacagc cgcugcgagu gccggcccaa gaaggaccgg      420

accaagccgg agaagaaguc ggugcgcggc aaggggaagg gccagaagcg gaagcggaag      480

aagagccgcu ucaagagcug gucgguccac ugcgagccgu gcagcgagcg gcggaagcac      540

cuguucgugc aggaccccca gacgugcaag ugcagcugca agaacaccga cucgcgcugc      600

aaggcccggc agcuggagcu caacgagcgg accugccgcu gcgacaagcc gcggcgguga      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5326
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt2)

<400>  5326
gggagaaagc uuaccaugga cuccgacgag accggcuucg agcacuccgg ccucuggguc       60

uccguccucg ccggccuccu ccucggcgcc ugccaggccc accccauccc cgacuccucc      120

ccccuccucc aguucggcgg ccagguccgc cagcgcuacc ucuacaccga cgacgcccag      180

cagaccgagg cccaccucga gauccgcgag gacggcaccg ucggcggcgc cgccgaccag      240

ucccccgagu cccuccucca gcucaaggcc cucaagcccg gcgucaucca gauccucggc      300

gucaagaccu cccgcuuccu cugccagcgc cccgacggcg cccucuacgg cucccuccac      360

uucgaccccg aggccugcuc cuuccgcgag cgccuccucg aggacggcua caacgucuac      420

caguccgagg cccacggccu cccccuccac cuccccggca acaagucccc ccaccgcgac      480

cccgcccccc gcggccccgc ccgcuuccuc ccccuccccg gccucccccc cgcccucccc      540

gagccccccg gcauccucgc cccccagccc cccgacgucg gcuccuccga cccccucucc      600

auggucggcg gcucccaggg ccgcuccccc uccuacgagu ccugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5327
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt2)

<400>  5327
gggagaaagc uuaccaugau guggggcacc aagcuccucc ccguccuccu ccuccagcac       60

guccuccucc accuccuccu ccuccacguc gccauccccu acgccgaggg ccagaagaag      120

cgccgcaaca cccuccacga guucaagaag uccgccaaga ccacccucac caaggaggac      180

ccccuccuca agaucaagac caagaagguc aacuccgccg acgagugcgc caaccgcugc      240

auccgcaacc gcggcuucac cuucaccugc aaggccuucg ucuucgacaa gucccgcaag      300

cgcugcuacu gguaccccuu caacuccaug uccuccggcg ucaagaaggg cuucggccac      360

gaguucgacc ucuacgagaa caaggacuac auccgcaacu gcaucaucgg caagggcggc      420

uccuacaagg gcaccgucuc caucaccaag uccggcauca agugccagcc cuggaacucc      480

augauccccc acgagcacuc cuuccucccc uccuccuacc gcggcaagga ccuccaggag      540

aacuacugcc gcaacccccg cggcgaggag ggcggccccu ggugcuucac cuccaacccc      600

gagguccgcu acgaggucug cgacaucccc cagugcuccg aggucgagug caugaccugc      660

aacggcgagu ccuaccgcgg ccccauggac cacaccgagu ccggcaagac cugccagcgc      720

ugggaccagc agacccccca ccgccacaag uuccuccccg agcgcuaccc cgacaagggc      780

uucgacgaca acuacugccg caaccccgac ggcaagcccc gccccuggug cuacacccuc      840

gaccccgaca cccccuggga guacugcgcc aucaagaccu gcgcccacuc cgccgucaac      900

gagaccgacg uccccaugga gaccaccgag ugcauccagg gccagggcga gggcuaccgc      960

ggcaccucca acaccaucug gaacggcauc cccugccagc gcugggacuc ccaguacccc     1020

cacaagcacg acaucacccc cgagaacuuc aagugcaagg accuccgcga gaacuacugc     1080

cgcaaccccg acggcgccga gucccccugg ugcuucacca ccgaccccaa cauccgcguc     1140

ggcuacugcu cccagauccc caagugcgac gucuccuccg gccaggacug cuaccgcggc     1200

aacggcaaga acuacauggg caaccucucc aagacccgcu ccggccucac cugcuccaug     1260

ugggacaaga acauggagga ccuccaccgc cacaucuucu gggagcccga cgccuccaag     1320

cucaacaaga acuacugccg caaccccgac gacgacgccc acggccccug gugcuacacc     1380

ggcaaccccc ucauccccug ggacuacugc cccaucuccc gcugcgaggg cgacaccacc     1440

cccaccaucg ucaaccucga ccaccccguc aucuccugcg ccaagaccaa gcagcuccgc     1500

gucgucaacg gcauccccac ccagaccacc gucggcugga uggucucccu caaguaccgc     1560

aacaagcaca ucugcggcgg cucccucauc aaggaguccu ggguccucac cgcccgccag     1620

ugcuuccccg cccgcaacaa ggaccucaag gacuacgagg ccuggcucgg cauccacgac     1680

guccacgagc gcggcgagga gaagcgcaag cagauccuca acaucuccca gcucgucuac     1740

ggccccgagg gcuccgaccu cguccuccuc aagcucgccc gccccgccau ccucgacaac     1800

uucgucucca ccaucgaccu ccccuccuac ggcugcacca uccccgagaa gaccaccugc     1860

uccaucuacg gcuggggcua caccggccuc aucaacgccg acggccuccu ccgcgucgcc     1920

caccucuaca ucaugggcaa cgagaagugc ucccagcacc accagggcaa ggucacccuc     1980

aacgaguccg agcucugcgc cggcgccgag aagaucggcu ccggccccug cgagggcgac     2040

uacggcggcc cccucaucug cgagcagcac aagaugcgca ugguccucgg cgucaucguc     2100

cccggccgcg gcugcgccau ccccaaccgc cccggcaucu ucguccgcgu cgccuacuac     2160

gccaagugga uccacaaggu cauccucacc uacaagcucu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5328
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt2)

<400>  5328
gggagaaagc uuaccauggg caagggcgac cccaagaagc cccgcggcaa gauguccucc       60

uacgccuucu ucguccagac cugccgcgag gagcacaaga agaagcaccc cgacgccucc      120

gucaacuucu ccgaguucuc caagaagugc uccgagcgcu ggaagaccau guccgccaag      180

gagaagggca aguucgagga cauggccaag gccgacaagg cccgcuacga gcgcgagaug      240

aagaccuaca ucccccccaa gggcgagacc aagaagaagu ucaaggaccc caacgccccc      300

aagcgccccc ccuccgccuu cuuccucuuc ugcuccgagu accgccccaa gaucaagggc      360

gagcaccccg gccucuccau cggcgacguc gccaagaagc ucggcgagau guggaacaac      420

accgccgccg acgacaagca gcccuacgag aagaaggccg ccaagcucaa ggagaaguac      480

gagaaggaca ucgccgccua ccgcgccaag ggcaagcccg acgccgccaa gaagggcguc      540

gucaaggccg agaaguccaa gaagaagaag gaggaggagg aggacgagga ggacgaggag      600

gacgaggagg aggaggagga cgaggaggac gaggacgagg aggaggacga cgacgacgag      660

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5329
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt2)

<400>  5329
gggagaaagc uuaccaugaa cuuccuccuc uccugggucc acuggacccu cgcccuccuc       60

cucuaccucc accacgccaa guggucccag gccgccccca ccaccgaggg cgagcagaag      120

ucccacgagg ucaucaaguu cauggacguc uaccagcgcu ccuacugccg ccccaucgag      180

acccucgucg acaucuucca ggaguacccc gacgagaucg aguacaucuu caagcccucc      240

ugcguccccc ucaugcgcug cgccggcugc ugcaacgacg aggcccucga gugcgucccc      300

accuccgagu ccaacaucac caugcagauc augcgcauca agccccacca gucccagcac      360

aucggcgaga uguccuuccu ccagcacucc cgcugcgagu gccgccccaa gaaggaccgc      420

accaagcccg agaagaaguc cguccgcggc aagggcaagg gccagaagcg caagcgcaag      480

aagucccgcu ucaaguccug guccguccac ugcgagcccu gcuccgagcg ccgcaagcac      540

cucuucgucc aggaccccca gaccugcaag ugcuccugca agaacaccga cucccgcugc      600

aaggcccgcc agcucgagcu caacgagcgc accugccgcu gcgacaagcc ccgccgcuga      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5330
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt3)

<400>  5330
gggagaaagc uuaccaugga cagcgaugag accggcuucg aacacuccgg gcugugggug       60

ucuguccucg ccggacuucu guugggugcu ugccaggcac aucccauccc ugacucaagu      120

ccauuacugc aauuuggcgg gcagguuaga cagagguacc uauauacaga ugacgcccag      180

caaacugagg cgcaccucga aauucgggag gauggaacgg ugggcggugc ugccgaccag      240

agcccggaau cccugcuuca gcugaaggca uugaaacccg ggguaauaca gauccucgga      300

gugaagaccu cucgcuuccu gugucaacga ccugauggcg cccuguacgg cucgcuccau      360

uuugacccag aggcuugcuc auuccgugag agauuacugg aagaugggua uaacgucuac      420

cagagcgagg cacacggacu ucccuugcau cugccuggua auaaaagucc acacagggac      480

cccgccccuc ggggcccagc ucgcuuucua ccgcuccccg ggcugccucc agcccuuccc      540

gaaccuccag gcauucuggc gccccagccg ccugaugugg gauccucuga ccccuugagc      600

augguuggug ggucccaggg aagaucacca aguuaugaga gcugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5331
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt3)

<400>  5331
gggagaaagc uuaccaugau guggggcacc aagcugcucc ccgugcuucu guugcagcac       60

gucuuacugc aucuacuccu gcuucacguu gccaucccuu acgcugaggg gcaaaagaag      120

agaaggaaca cacugcauga guucaaaaag agcgcaaaaa cuacguugac caaggaggac      180

ccacuccuga agauuaaaac aaagaaagua aauuccgccg augaaugcgc gaaccggugu      240

auacgcaauc gaggauuuac uuuuaccugc aaggcuuucg uguucgacaa aucucguaag      300

agauguuauu gguacccguu uaacucaaug aguagcggug ugaagaaagg cuucgggcac      360

gaguuugauc uguaugaaaa uaaggacuac aucaggaacu gcauuaucgg aaaaggcggu      420

uccuauaagg ggacagucuc uauuaccaaa ucgggaauca agugucagcc cuggaacuca      480

augauaccuc augagcacag cuuccuccca aguuccuacc ggggcaaaga uuuacaggag      540

aauuauugcc gcaaucccag aggcgaagaa gggggaccuu gguguuuuac uucuaaccca      600

gaagugaggu acgagguuug cgacaucccc caguguagcg agguggaaug caugacaugu      660

aauggugagu ccuaccgggg cccuauggau cacaccgaau cagggaagac gugccaacgc      720

ugggaccagc agacuccaca ucgacacaag uuccugccgg agagauaucc cgauaaagga      780

uuugacgaua acuacugcag gaauccugac ggcaagccac ggcccuggug uuauacccuu      840

gauccugaca caccauggga auacugcgcc auuaaaacuu gugcacauag ugccgucaac      900

gagaccgacg ugcccaugga gacaaccgaa ugcauccagg gucaagggga gggauaucgu      960

ggcacgagca auacuauuug gaacggcauc ccgugucagc gcugggauuc ucaguacccu     1020

cacaagcacg acauaacacc cgaaaacuuc aaaugcaagg auuugagaga gaauuauugu     1080

aggaacccag acggggcuga auccccuugg ugcuuuacca cugaucccaa uauucgggua     1140

ggauacuguu cacagauccc aaagugcgac guuagcagug gucaagauug uuaccgaggc     1200

aacgggaaaa auuauauggg aaaccugucu aagacacgcu ccggccuaac cugcagcaug     1260

ugggacaaaa auauggagga ucuccauaga cacauuuucu gggagcccga cgcaucgaag     1320

cugaacaaaa auuacugcag gaacccugau gacgacgccc augguccaug guguuauacg     1380

gggaauccgc uuauccccug ggauuacugc ccuaucucuc ggugugaagg cgacaccaca     1440

ccaacuauug ugaaccugga ucaccccguc auauccugcg cuaagaccaa gcaguugcgc     1500

guggugaaug gaaucccuac acagacuacc gucggcugga ugguuucacu caaauauaga     1560

aacaagcaua uuuguggggg aagucugauc aaagagagcu ggguguuaac agccaggcaa     1620

ugcuucccag cgcguaauaa ggaccugaaa gauuacgaag cauggcucgg uauacacgac     1680

guacacgagc ggggcgaaga gaagcgaaag cagauucuua acaucuccca gcugguguau     1740

gggcccgagg gaucugauuu gguccuacug aaacucgcca gaccggcuau ccuggacaac     1800

uuugugagca ccauugaucu uccuucauac ggcuguacua ucccagaaaa gacgacaugc     1860

aguauuuacg guugggggua uaccggccug auaaaugccg acggauugcu caggguugca     1920

caucuguaca ucaugggcaa cgagaaaugu ucccagcacc aucaagggaa ggugacuuua     1980

aaugaaagcg agcugugcgc uggagccgag aaaauugguu cuggccccug ugaaggggau     2040

uauggaggcc cucuaaucug cgagcagcac aagaugcgca ugguccucgg ugugaucgua     2100

cccgggcggg gcugcgcgau uccaaacaga ccuggaauau ucguuagggu ggccuacuau     2160

gcaaaaugga uccacaaggu cauucugacc uacaaacuuu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5332
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt3)

<400>  5332
gggagaaagc uuaccauggg caagggggac cccaaaaagc cuagaggaaa aaugagcucc       60

uacgccuucu uugugcagac cugcagggag gaacacaaga aaaagcaucc agaugcuucu      120

gucaacuucu cagaguuuag uaagaaaugu agcgaacggu ggaagacaau guccgcaaaa      180

gagaagggua aauucgaaga cauggccaag gcggauaagg cucgcuauga gcgagagaug      240

aaaacuuaca ucccgcccaa gggcgaaacg aaaaagaaau uuaaggaccc uaaugcccca      300

aaacgucccc cuucugcauu cuuucuguuc ugcucggagu auagaccaaa gauuaagggg      360

gaacaccccg gacucucaau aggcgauguu gccaagaaac uuggugagau guggaacaau      420

accgcugcag acgauaaaca accuuacgag aagaaagccg cuaagcugaa ggaaaaauau      480

gagaaggaca ucgccgcgua cagggcaaaa gggaagccag augccgcuaa aaagggagug      540

guaaaggccg agaaaagcaa gaaaaagaaa gaagaagagg aggacgaaga ggaugaagag      600

gacgaagagg aggaagagga ugaagaggac gaagacgagg aggaagauga cgaugacgag      660

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5333
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt3)

<400>  5333
gggagaaagc uuaccaugaa cuuccugcuc agcugggugc acuggacccu ugcccuguug       60

uuauaccugc aucacgcuaa guggucccag gcagccccca caacugaggg cgaacaaaaa      120

ucucaugagg ucaucaaguu uauggacguu uaucagagau cauacugcag gccuauugaa      180

acgcuagugg auauauucca ggaguaucca gacgaaaucg aguacauuuu uaaaccgagu      240

uguguacccc ucaugcggug cgcggggugu ugcaaugaug aggcucugga augugugccu      300

accagcgagu ccaacaucac aaugcagauu augcgcauca agccacacca aucucagcau      360

auaggagaaa ugucguuccu ucagcacuca cgaugcgagu gucgucccaa aaaggacaga      420

acuaagccug agaaaaagag cgucaggggu aaaggcaagg ggcagaaacg gaagcgcaag      480

aaaaguagau uuaaguccug gucugugcac ugcgaaccau guagcgagag gcggaaacau      540

cuguucguuc aagaucccca gaccugcaag uguuccugca aaaauacaga cucacgcugc      600

aaggcccgac aguuggaacu caacgagaga accuguaggu gcgauaaacc ucggcguuga      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5334
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt4)

<400>  5334
gggagaaagc uuaccaugga cagcgacgag accggcuucg agcacagcgg ccugugggug       60

agcgugcugg ccggccugcu gcugggcgcc ugccaggccc accccauccc cgacagcagc      120

ccccugcugc aguucggcgg ccaggugaga cagagauacc uguacaccga cgacgcccag      180

cagaccgagg cccaccugga gaucagagag gacggcaccg ugggcggcgc cgccgaccag      240

agccccgaga gccugcugca gcugaaggcc cugaagcccg gcgugaucca gauccugggc      300

gugaagacca gcagauuccu gugccagaga cccgacggcg cccuguacgg cagccugcac      360

uucgaccccg aggccugcag cuucagagag agacugcugg aggacggcua caacguguac      420

cagagcgagg cccacggccu gccccugcac cugcccggca acaagagccc ccacagagac      480

cccgccccca gaggccccgc cagauuccug ccccugcccg gccugccccc cgcccugccc      540

gagccccccg gcauccuggc cccccagccc cccgacgugg gcagcagcga cccccugagc      600

auggugggcg gcagccaggg cagaagcccc agcuacgaga gcugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5335
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt4)

<400>  5335
gggagaaagc uuaccaugau guggggcacc aagcugcugc ccgugcugcu gcugcagcac       60

gugcugcugc accugcugcu gcugcacgug gccauccccu acgccgaggg ccagaagaag      120

agaagaaaca cccugcacga guucaagaag agcgccaaga ccacccugac caaggaggac      180

ccccugcuga agaucaagac caagaaggug aacagcgccg acgagugcgc caacagaugc      240

aucagaaaca gaggcuucac cuucaccugc aaggccuucg uguucgacaa gagcagaaag      300

agaugcuacu gguaccccuu caacagcaug agcagcggcg ugaagaaggg cuucggccac      360

gaguucgacc uguacgagaa caaggacuac aucagaaacu gcaucaucgg caagggcggc      420

agcuacaagg gcaccgugag caucaccaag agcggcauca agugccagcc cuggaacagc      480

augauccccc acgagcacag cuuccugccc agcagcuaca gaggcaagga ccugcaggag      540

aacuacugca gaaaccccag aggcgaggag ggcggccccu ggugcuucac cagcaacccc      600

gaggugagau acgaggugug cgacaucccc cagugcagcg agguggagug caugaccugc      660

aacggcgaga gcuacagagg ccccauggac cacaccgaga gcggcaagac cugccagaga      720

ugggaccagc agacccccca cagacacaag uuccugcccg agagauaccc cgacaagggc      780

uucgacgaca acuacugcag aaaccccgac ggcaagccca gacccuggug cuacacccug      840

gaccccgaca cccccuggga guacugcgcc aucaagaccu gcgcccacag cgccgugaac      900

gagaccgacg ugcccaugga gaccaccgag ugcauccagg gccagggcga gggcuacaga      960

ggcaccagca acaccaucug gaacggcauc cccugccaga gaugggacag ccaguacccc     1020

cacaagcacg acaucacccc cgagaacuuc aagugcaagg accugagaga gaacuacugc     1080

agaaaccccg acggcgccga gagccccugg ugcuucacca ccgaccccaa caucagagug     1140

ggcuacugca gccagauccc caagugcgac gugagcagcg gccaggacug cuacagaggc     1200

aacggcaaga acuacauggg caaccugagc aagaccagaa gcggccugac cugcagcaug     1260

ugggacaaga acauggagga ccugcacaga cacaucuucu gggagcccga cgccagcaag     1320

cugaacaaga acuacugcag aaaccccgac gacgacgccc acggccccug gugcuacacc     1380

ggcaaccccc ugauccccug ggacuacugc cccaucagca gaugcgaggg cgacaccacc     1440

cccaccaucg ugaaccugga ccaccccgug aucagcugcg ccaagaccaa gcagcugaga     1500

guggugaacg gcauccccac ccagaccacc gugggcugga uggugagccu gaaguacaga     1560

aacaagcaca ucugcggcgg cagccugauc aaggagagcu gggugcugac cgccagacag     1620

ugcuuccccg ccagaaacaa ggaccugaag gacuacgagg ccuggcuggg cauccacgac     1680

gugcacgaga gaggcgagga gaagagaaag cagauccuga acaucagcca gcugguguac     1740

ggccccgagg gcagcgaccu ggugcugcug aagcuggcca gacccgccau ccuggacaac     1800

uucgugagca ccaucgaccu gcccagcuac ggcugcacca uccccgagaa gaccaccugc     1860

agcaucuacg gcuggggcua caccggccug aucaacgccg acggccugcu gagaguggcc     1920

caccuguaca ucaugggcaa cgagaagugc agccagcacc accagggcaa ggugacccug     1980

aacgagagcg agcugugcgc cggcgccgag aagaucggca gcggccccug cgagggcgac     2040

uacggcggcc cccugaucug cgagcagcac aagaugagaa uggugcuggg cgugaucgug     2100

cccggcagag gcugcgccau ccccaacaga cccggcaucu ucgugagagu ggccuacuac     2160

gccaagugga uccacaaggu gauccugacc uacaagcugu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5336
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt4)

<400>  5336
gggagaaagc uuaccauggg caagggcgac cccaagaagc ccagaggcaa gaugagcagc       60

uacgccuucu ucgugcagac cugcagagag gagcacaaga agaagcaccc cgacgccagc      120

gugaacuuca gcgaguucag caagaagugc agcgagagau ggaagaccau gagcgccaag      180

gagaagggca aguucgagga cauggccaag gccgacaagg ccagauacga gagagagaug      240

aagaccuaca ucccccccaa gggcgagacc aagaagaagu ucaaggaccc caacgccccc      300

aagagacccc ccagcgccuu cuuccuguuc ugcagcgagu acagacccaa gaucaagggc      360

gagcaccccg gccugagcau cggcgacgug gccaagaagc ugggcgagau guggaacaac      420

accgccgccg acgacaagca gcccuacgag aagaaggccg ccaagcugaa ggagaaguac      480

gagaaggaca ucgccgccua cagagccaag ggcaagcccg acgccgccaa gaagggcgug      540

gugaaggccg agaagagcaa gaagaagaag gaggaggagg aggacgagga ggacgaggag      600

gacgaggagg aggaggagga cgaggaggac gaggacgagg aggaggacga cgacgacgag      660

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5337
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt4)

<400>  5337
gggagaaagc uuaccaugaa cuuccugcug agcugggugc acuggacccu ggcccugcug       60

cuguaccugc accacgccaa guggagccag gccgccccca ccaccgaggg cgagcagaag      120

agccacgagg ugaucaaguu cauggacgug uaccagagaa gcuacugcag acccaucgag      180

acccuggugg acaucuucca ggaguacccc gacgagaucg aguacaucuu caagcccagc      240

ugcgugcccc ugaugagaug cgccggcugc ugcaacgacg aggcccugga gugcgugccc      300

accagcgaga gcaacaucac caugcagauc augagaauca agccccacca gagccagcac      360

aucggcgaga ugagcuuccu gcagcacagc agaugcgagu gcagacccaa gaaggacaga      420

accaagcccg agaagaagag cgugagaggc aagggcaagg gccagaagag aaagagaaag      480

aagagcagau ucaagagcug gagcgugcac ugcgagcccu gcagcgagag aagaaagcac      540

cuguucgugc aggaccccca gaccugcaag ugcagcugca agaacaccga cagcagaugc      600

aaggccagac agcuggagcu gaacgagaga accugcagau gcgacaagcc cagaagauga      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5338
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt5)

<400>  5338
gggagaaagc uuaccaugga cagcgaugag accggcuucg aacacuccgg gcugugggug       60

ucuguccucg ccggacugcu ucugggcgcu ugccaggccc aucccauccc ugacagcucc      120

ccgcuccugc aauuuggggg acagguuaga cagcgguacc uuuauacaga ugacgcgcag      180

caaacggagg cucaccugga aauucgcgag gauggcaccg ugggcggagc cgccgaccag      240

ucucccgaaa gccuccugca gcugaaggcu cucaaaccug gcgugaucca gauucugggc      300

gucaagacau ccagauuccu uugucaacgg cccgaugggg cccuguacgg aucucuccau      360

uuugacccug aggcuugcag cuuccgcgag agacugcuug aagauggcua uaacguguac      420

caguccgagg cccacgggcu gccccuccau cugccuggaa auaaaagccc gcaccgggac      480

cccgcgccuc gcggccccgc cagauuucug ccucuccccg ggcugccgcc ugcccuuccc      540

gaaccucccg gaauccuggc uccccagccu ccggauguug ggucuuccga cccccucagc      600

auggugggcg ggucucaggg acgguccccu agcuaugagu cuugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5339
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt5)

<400>  5339
gggagaaagc uuaccaugau guggggcacc aagcugcucc ccgugcugcu ucugcagcac       60

guccuccugc aucuucugcu ccugcacguu gccaucccuu acgcugaggg gcagaaaaag      120

agacggaaca cacugcauga guucaaaaag agcgccaaaa cgacccucac aaaggaagac      180

ccgcugcuua agauuaaaac caagaaaguc aauuccgcgg augaaugcgc uaaccgcugu      240

aucagaaauc ggggauuuac auuuaccugc aaggccuucg uguucgacaa aucucgcaag      300

agauguuauu gguaccccuu uaacagcaug uccucuggcg ugaagaaagg guucggacac      360

gaguuugauc uguaugaaaa uaaggacuac auucggaacu gcaucauugg caaaggggga      420

agcuauaagg gcacaguguc caucaccaaa ucuggcauca agugucaacc uuggaauagc      480

augauucccc augagcacuc cuuccucccu agcucuuacc gcgggaaaga ucugcaggag      540

aacuauugca gaaauccccg gggagaagag ggcgggccuu gguguuuuac guccaacccg      600

gaaguucgcu acgaggugug cgacaucccc caguguagcg aggucgaaug caugaccugu      660

aauggagagu cuuacagagg cccuauggau cacacagaau ccgggaagac cugccaacgg      720

ugggaccagc agacacccca ucgccacaag uuccuuccug agagauaucc cgauaaagga      780

uuugacgaua acuacugccg gaauccggac ggcaagccuc gccccuggug uuauacccug      840

gauccugaca cgcccuggga auacugcgcc auuaaaacau gugcucauag cgccgugaac      900

gagaccgacg uucccaugga gacaaccgaa ugcauccagg gccaagggga gggauauaga      960

ggcaccucua auacaauuug gaacgggauc ccuugucagc ggugggauuc ccaguacccg     1020

cacaagcacg acauuacgcc cgaaaacuuc aaaugcaagg aucucagaga gaauuauugu     1080

cgcaacccug acggagcuga aagccccugg ugcuuuacca cagauccuaa uauccgggug     1140

ggcuacuguu cccagauccc caagugcgac gucucuagcg ggcaagauug uuacagagga     1200

aacggcaaaa auuauauggg caaccugucc aagacccgca gcgggcugac augcucuaug     1260

ugggacaaaa auauggagga ucuccaucgg cacauuuucu gggagccgga cgccuccaag     1320

cugaacaaaa auuacugcag aaacccugau gacgacgcgc auggacccug guguuauacc     1380

ggcaauccuc uuauccccug ggauuacugc ccuauuagcc gcugugaagg ggacacgaca     1440

cccaccaucg ugaaccugga ucacccggug auuucuugcg ccaagaccaa gcagcuccgg     1500

gucguuaaug gaaucccuac acagaccaca gugggcugga uggugagccu gaaauauaga     1560

aacaagcaua ucuguggggg cucccuuauu aaagagucuu ggguccugac ggcucgccaa     1620

ugcuuccccg cccggaauaa ggaccucaaa gauuacgagg cuuggcuggg aauccacgac     1680

gugcacgaaa gaggcgaaga gaagcgcaag cagauucuga acaucagcca gcucguuuau     1740

gggcccgagg gauccgaucu ggugcuucug aaacucgccc ggccugcgau ucuggacaac     1800

uuugucagca ccaucgaucu uccgucuuac ggcuguacaa uccccgaaaa gaccacaugc     1860

uccauuuacg gguggggaua uaccggccug aucaaugccg acgggcuccu gagaguggcu     1920

caucuguaca uuaugggcaa cgagaaaugu agccagcacc aucaaggaaa gguuacgcuc     1980

aaugaaucug agcugugcgc cggcgcugag aaaaucgggu ccggaccuug ugaaggcgau     2040

uaugggggac cccuuauuug cgagcagcac aagaugcgga uggugcuggg cgucaucgug     2100

ccugggcgcg gcugcgccau ucccaacaga ccuggaaucu ucguccgggu ggccuacuau     2160

gcuaaaugga uccacaaggu uauucucacc uacaagcugu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5340
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt5)

<400>  5340
gggagaaagc uuaccauggg caagggggac cccaaaaagc cuagaggaaa aaugagcucc       60

uacgccuucu uugugcagac cugccgggag gaacacaaga aaaagcaucc ggaugcuucu      120

gucaacuuca gcgaguuuuc caagaaaugu ucugaacgcu ggaagacaau gagcgccaaa      180

gagaagggca aauucgaaga cauggcgaag gcugauaagg ccagauauga gcgggagaug      240

aaaacguaca uucccccuaa gggggaaacc aaaaagaaau uuaaggaccc caaugccccu      300

aaaagacccc cuuccgcuuu cuuucuguuc ugcucugagu aucgcccgaa gaucaaggga      360

gaacaccccg gccucagcau cggggauguu gccaaaaagc ugggagagau guggaacaau      420

acagcugccg acgauaaaca accuuacgag aagaaagcgg ccaaacuuaa ggaaaaguau      480

gagaaggaca uugcugccua ccgggcuaaa ggcaagcccg augccgcgaa aaagggcgug      540

gugaaggccg aaaaauccaa gaaaaagaaa gaggaagagg aggacgaaga ggaugaagag      600

gacgaagagg aggaagagga ugaagaggac gaagacgagg aggaagauga cgaugacgag      660

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5341
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt5)

<400>  5341
gggagaaagc uuaccaugaa cuuccugcuc agcugggugc acuggacccu ggcccuucug       60

cucuaccugc aucacgcuaa guggucccag gccgcgccca caacggaggg cgaacaaaaa      120

ucucaugagg ucaucaaguu uauggacguu uaucagagaa gcuacugccg gccuauugaa      180

acccuugugg auaucuucca ggaguauccg gacgaaauug aguacaucuu uaaacccucc      240

ugugugccuc ugaugcgcug cgcugggugu ugcaaugaug aggcccucga augugucccc      300

acaucugaga gcaacauuac caugcagauc augagaauca agccucacca aucccagcau      360

auuggagaaa ugucuuuccu gcagcacagc cggugcgagu gucgccccaa aaaggacaga      420

acaaagccug agaaaaaguc cgugcggggc aaagggaagg gacagaaacg caagagaaag      480

aaaagccggu uuaagucuug guccguucac ugcgaaccgu guagcgagcg cagaaaacau      540

cuguucgugc aagaucccca gaccugcaag uguucuugca aaaauacaga cucccggugc      600

aaggcccgcc agcucgaacu gaacgagaga accugucggu gcgauaaacc ucgcagauga      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5342
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt6)

<400>  5342
gggagaaagc uuaccaugga uucagaugaa acaggauuug aacacucagg auuauggguc       60

ucaguuuuag caggacuauu acuaggagca ugucaagcac auccaauacc agacucaagc      120

ccauuauuac aauuuggagg acaaguaaga caaagauauu uauauacaga ugacgcacaa      180

caaacagaag cacauuuaga aauaagagaa gacggcacag uaggaggagc agcagaucaa      240

ucaccagaau cacuauuaca auuaaaagca uuaaaaccag gaguaauaca aauauuagga      300

guaaaaacau caagauucuu augccaaaga ccugacggag cauuauaugg uucacuacac      360

uuugacccag aagcauguuc auucagagaa agacuacuag aagacggaua uaauguuuac      420

caaucugaag cacauggauu accacuacac uuaccaggaa auaaaucacc acaccgagac      480

ccagcaccac gaggaccagc aagauuccua ccacuaccag gauuaccacc agcauuacca      540

gaaccaccag gaauacuagc uccacaacca ccagacguag gauccucaga uccauuauca      600

augguaggag gaucucaagg uagaaguccc ucauacgaau cauaaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5343
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt6)

<400>  5343
gggagaaagc uuaccaugau guggggaaca aaacuauuac caguauuauu auuacaacau       60

gucuuauuac auuuacuucu acuacauguu gcaauacccu augccgaagg acaaaagaaa      120

agaagaaaca cucuucacga guucaagaaa agcgcaaaaa caacauuaac aaaagaagac      180

ccacuacuaa aaauaaaaac aaagaaagua aacucagcag augaaugugc caacagaugu      240

auuagaaacc gggguuuuac uuuuacaugc aaagccuucg uauucgauaa aucaaggaaa      300

agaugcuacu gguauccauu caauucaaug ucauccggag ucaagaaagg auucggccau      360

gaauuugacc uauacgaaaa uaaagauuau aucagaaacu guauaauagg aaaagguggu      420

ucauacaaag gaacaguauc aauaacaaaa agcgguauua aaugucaacc cuggaacucu      480

augauuccuc augaacauuc auuuuuacca ucaucauaca gagguaaaga cuuacaagaa      540

aauuacugca gaaauccaag gggagaagaa ggcggaccau ggugcuuuac aucaaauccc      600

gaaguaagau augaaguaug cgacauacca caauguagug aaguugaaug uaugacaugu      660

aauggagaaa gcuacagagg uccaauggau cauacagaau caggaaaaac augccaaaga      720

ugggaucaac aaacaccgca uagacauaaa uuuuuaccag aaagauaucc agauaaagga      780

uucgaugaca auuacuguag gaaucccgac ggaaaaccac gaccauggug cuauacacua      840

gacccugaua cuccauggga auauugcgcu auaaaaacuu gugcacauuc agcaguaaac      900

gaaaccgacg uaccaaugga aaccacugaa uguauacaag ggcaaggaga aggauacaga      960

ggaacaucaa auacaauaug gaacggaaua cccugucaaa gaugggauag ccaauaucca     1020

cauaaacacg acauaacccc agaaaacuuu aaauguaaag aucuaagaga aaauuacugc     1080

agaaaucccg auggcgcaga aucaccaugg ugcuucacaa cagaucccaa cauaagaguc     1140

ggauauugcu cccagauucc uaaaugugau guaagcuccg ggcaagacug cuaccgaggc     1200

aacgguaaaa auuacauggg aaacuuaagu aaaacaagau caggauuaac augcaguaug     1260

ugggauaaaa auauggagga cuuacauaga cauauauucu gggaaccaga ugcaucaaaa     1320

cuuaacaaaa auuauugcag aaacccagac gacgaugcac acggaccaug guguuauaca     1380

ggaaauccac uuauaccaug ggacuauugu ccaauaucac gaugcgaagg agauacaaca     1440

ccaacaauag uaaacuuaga ucauccagua auaaguugcg caaaaacuaa acaauuacga     1500

guuguuaacg gaauaccaac acaaacuaca gucggaugga ugguuucauu aaaauauaga     1560

aacaaacaca uaugcggagg aucccuuaua aaagaauccu ggguauuaac agcaagacaa     1620

uguuuuccag ccagaaauaa agaucucaaa gacuacgaag caugguuagg cauacacgau     1680

guacaugaac gaggagaaga aaaacgaaaa caaauauuaa auauaagcca gcuaguuuau     1740

ggaccagaag gaucggacuu aguacuauua aaacuugcaa gaccagcaau ccuagacaau     1800

uuugucucaa caaucgacuu acccucauau ggaugcacua uuccggagaa aacaacaugc     1860

uccauauacg gauggggaua uacaggauug auaaaugcag auggauuacu aagaguagca     1920

caucuauaca uaaugggaaa ugaaaaaugu ucacaacacc aucaaggaaa aguaacacua     1980

aacgaaagcg aauuaugugc aggcgcagag aaaauaggca guggaccaug ugaaggagau     2040

uacgguggac cacuaauaug cgaacaacau aaaaugagaa ugguccuagg aguaauaguc     2100

cccggaagag gaugugcaau accaaaucga ccgggcauau uuguaagagu agcauacuac     2160

gcaaaaugga uacacaaagu aauacuaaca uacaaacuau aaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5344
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt6)

<400>  5344
gggagaaagc uuaccauggg aaaaggagac ccaaaaaaac caagaggaaa aaugucaagc       60

uacgcauucu ucguacaaac augcagagaa gaacacaaaa aaaaacaccc agacgcaagc      120

guaaacuuca gcgaauucag caaaaaaugu ucagaaagau ggaaaacaau gagcgcaaaa      180

gaaaaaggaa aauucgaaga cauggcaaaa gcagacaaag caagauacga aagagaaaug      240

aaaacauaca uaccaccaaa aggagaaaca aaaaaaaaau ucaaagaccc aaacgcgcca      300

aaaagaccac caucagcauu cuucuuauuc ugcagugaau acagaccaaa aauaaaagga      360

gaacacccag gacuaaguau aggagacgua gcaaaaaaac uaggagaaau guggaacaac      420

acagcagcag acgacaaaca accauacgaa aaaaaagcag caaaacuaaa agaaaaauac      480

gaaaaagaca uagcggcaua cagagcaaaa ggaaaaccag acgcagcaaa aaaaggagua      540

guaaaagcag aaaaaaguaa aaaaaaaaaa gaagaagaag aagacgaaga agacgaagaa      600

gacgaagaag aagaagaaga cgaagaagac gaagacgaag aagaagacga cgacgacgaa      660

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5345
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt6)

<400>  5345
gggagaaagc uuaccaugaa cuuccuauua agcuggguac acuggacacu agcacuacua       60

cuauacuuac accacgccaa auggagccaa gcagcaccaa caacagaagg agaacaaaaa      120

ucacacgaag uaauaaaauu cauggacgua uaccaaagau cauacuguag accaauagaa      180

acacuaguag acauauucca agaauaccca gacgaaauag aauacauauu caaaccauca      240

ugcguaccac uaaugagaug cgcaggaugc ugcaacgacg aagcacuaga augcguacca      300

acaucagaau caaacauaac aaugcaaaua augagaauaa aaccacacca aagucaacac      360

auaggagaaa ugaguuuccu acaacacuca agaugcgaau gcagaccaaa aaaagacaga      420

acaaaaccag aaaaaaaauc aguaagagga aaaggaaaag gccaaaaaag aaaaagaaaa      480

aaaucaagau ucaaaagcug gucaguacac ugugaaccau guucagaaag aagaaaacac      540

cuauucguac aagacccaca aacaugcaaa ugcaguugca aaaacacaga cucaagaugc      600

aaagcaagac aacuagaauu aaaugaacga acaugcagau gcgacaaacc aagaagauaa      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5346
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt7)

<400>  5346
gggagaaagc uuaccaugga cagcgaugag accggcuucg aacacuccgg gcugugggug       60

aguguccucg ccggucuguu gcugggcgca ugccaggccc aucccauccc agacagcucc      120

ccgcuccugc aauuuggggg ccaggugagg cagcgguacu uguauacuga ugacgcgcag      180

caaaccgagg cccaccugga aauucgcgag gaugguacgg uagggggcgc agccgaccag      240

agucccgaaa gccuccugca gcugaaggca cucaaaccag gcgugaucca gauucugggg      300

gucaagacuu ccagguucuu gugucaacgg cccgauggug cccuguacgg cagccuccau      360

uuugacccag aggcgugcuc cuuccgcgag aggcugcugg aagaugggua uaacguguac      420

cagagugagg cccacggcuu gccccuccau cugccaggua auaaaagccc gcaccgggac      480

cccgcaccac gcgggcccgc cagguuucug ccacuccccg gccugccgcc cgccuugcca      540

gaacccccag gcauccuggc accccagcca ccggaugugg gguccagcga cccccucagu      600

auggucggug gcucccaggg gcggagccca uccuaugaga guugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5347
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt7)

<400>  5347
gggagaaagc uuaccaugau guggggcacc aagcugcucc ccgugcuguu gcugcagcac       60

guccuccugc auuugcugcu ccugcacgug gccaucccau acgcagaggg gcagaaaaag      120

aggcggaaca cucugcauga guucaaaaag agcgccaaaa ccacgcucac uaaggaggac      180

ccgcuguuga agauuaaaac caagaaagua aauuccgcgg augaaugcgc caaccgcugu      240

aucaggaauc gggguuuuac cuucacuugc aaggcauuug uguucgacaa aagucgcaag      300

agguguuauu gguaccccuu uaacagcaug uccaguggcg ucaaaaaggg guucggccac      360

gaguuugauc uguaugaaaa uaaggacuac auucggaacu gcaucauugg uaaagggggc      420

agcuauaagg gcaccguguc caucacgaaa agcgggauca agugucaacc auggaacucc      480

augauucccc augagcacag uuuccuccca agcuccuacc gcgguaaaga ucugcaggag      540

aauuauugca ggaauccccg gggcgaagaa gggggcccau gguguuuuac uagcaacccg      600

gaagugcgcu acgaggucug cgacaucccc caguguagug agguggaaug caugaccugc      660

aauggugagu ccuacagggg gccaauggau cacacugaaa gcggcaagac cugucaacgg      720

ugggaccagc agacucccca ucgccacaag uuccugccag agagguaucc cgauaaaggc      780

uuugacgaua acuacugccg gaauccggac gggaagcccc gcccauggug uuauacguug      840

gaucccgaca cuccauggga auacugcgcc auuaaaaccu gugcacauuc cgccguaaac      900

gagacugacg ugcccaugga gaccaccgaa ugcauccagg gucaaggcga gggguauagg      960

ggcaccagua auacgauuug gaacgguauc ccaugucagc ggugggauag ccaguacccg     1020

cacaagcacg acauuacccc cgaaaacuuc aaaugcaagg aucuccgcga gaauuauugu     1080

aggaacccag acggcgcgga aucccccugg ugcuucacua ccgauccaaa uauccggguc     1140

ggguacugca gccagauccc caagugugac gugaguuccg gccaagauug cuacaggggg     1200

aacgguaaaa auuauauggg caaccugagc aagacccgca gugggcugac uuguuccaug     1260

ugggacaaaa auauggagga ucuccaucgg cacaucuuuu gggagccgga cgccagcaag     1320

cugaacaaaa auuacugcag gaacccagau gacgacgcac auggccccug guguuauacg     1380

gguaaucccu ugauuccaug ggauuacugc cccauuagcc gcugugaagg cgacaccacu     1440

ccaaccaucg ugaaccugga ucacccgguc auuuccugcg ccaagaccaa gcagcuccgg     1500

gugguaaaug ggauccccac ucagacgacc gugggcugga uggucagucu gaaauauagg     1560

aacaagcaua ucuguggggg cagccugauu aaagaguccu ggguguugac ugcccgccaa     1620

ugcuucccag cacggaauaa ggaccucaaa gauuacgaag ccuggcuggg uauccacgac     1680

gugcacgaga ggggcgaaga gaagcggaaa cagauucuga acaucagcca gcucgucuau     1740

gggcccgagg guagugaucu gguguugcug aagcucgcgc gcccagccau ucuggacaac     1800

uuuguaucca ccaucgaucu gcccagcuac ggcuguacua ucccggaaaa gaccacgugc     1860

uccauuuacg gguggggcua uaccggguug aucaaugcag acggccuccu gaggguggcc     1920

caucuguaca uuauggguaa cgagaaaugc agucagcacc aucaagggaa ggucacucuc     1980

aaugaaagcg agcugugugc aggcgccgag aaaaucggcu ccgggccaug cgaaggugau     2040

uauggcgggc ccuugauuug ugagcagcac aagaugcgga uggugcuggg cgucaucgug     2100

ccaggucgcg ggugcgccau ucccaacagg ccgggcaucu ucgugcgggu agcguacuau     2160

gcaaaaugga uccacaaggu gauucucacc uacaagcugu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5348
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt7)

<400>  5348
gggagaaagc uuaccauggg caagggggac cccaaaaagc caagggguaa aaugagcucc       60

uacgccuucu uugugcagac cugccgggag gaacacaaga aaaagcaucc ggaugcaagu      120

gucaacuuca gcgaguuuuc caagaaaugu agugaacgcu ggaagacuau gagcgccaaa      180

gagaagggca aauucgaaga cauggcgaag gccgauaaag caagguauga gcgggagaug      240

aagaccuaca uucccccaaa gggggaaacg aaaaagaaau uuaaggaccc caaugcccca      300

aaaaggcccc cauccgcauu cuuucuguuc ugcagcgagu aucgcccgaa gaucaagggc      360

gaacaccccg gucucuccau cggggaugug gccaaaaagc ugggcgagau guggaacaau      420

acugcggccg acgauaaaca accauacgag aagaaagcag ccaaguugaa ggaaaaauau      480

gagaaggaca uugccgcaua ccgggccaaa ggcaagcccg augcggccaa aaagggggua      540

gugaaggcag agaaaaguaa gaaaaagaaa gaagaagagg aggacgaaga ggaugaagag      600

gacgaagagg aggaagagga ugaagaggac gaagacgagg aggaagauga cgaugacgag      660

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5349
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt7)

<400>  5349
gggagaaagc uuaccaugaa cuuccugcuc agcugggugc acuggacccu ggccuugcug       60

cucuaccugc aucacgcaaa guggucccag gccgcgccca cuaccgaggg cgaacagaaa      120

agucaugagg ucaucaaguu uauggacgug uaucaaagga gcuacugccg gccaauugaa      180

acguugguag auaucuucca ggaguauccg gacgaaauug aguacaucuu uaaacccucc      240

ugugugccac ugaugcgcug cgccgggugu ugcaaugaug aggcacucga augugucccc      300

accagugaga gcaacauuac uaugcagauc augaggauca agccacacca aucccagcau      360

auuggugaaa ugagcuuccu gcagcacucc cggugcgagu gucgccccaa aaaggacagg      420

accaagccag agaaaaagag ugugcggggc aaagggaagg gccagaaacg caagaggaaa      480

aagagccggu uuaaguccug gagcgugcac ugcgaaccgu guagugagcg caggaaacau      540

cuguucgucc aagaucccca gacuugcaag ugcuccugua aaaauaccga cagccggugc      600

aaggcccgcc agcucgaacu gaacgagagg acgugucggu gcgauaaacc aaggcgcuga      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5350
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt8)

<400>  5350
gggagaaagc uuaccaugga cucugacgaa accggcuucg aacacuccgg acucuggguc       60

uccguccucg ccggccuccu ccuaggcgcc ugccaagccc accccauccc cgacucaucc      120

ccacuccuac aauucggcgg ccaaguccgu caacgcuacc ucuauaccga ugacgcccaa      180

caaaccgaag cccaccucga aauccgcgaa gacggaaccg ucggcggcgc cgcugaccaa      240

ucacccgaau cccuccucca acucaaagca cucaaacccg gcguaaucca aauccucggc      300

guaaaaaccu cacgauuucu augucaaaga cccgacggag cccuauacgg cucucuacac      360

uucgacccag aagcaugcuc cuuccgcgaa cgacuccucg aagacggaua caacgucuac      420

caaucagaag cccacggccu accccuccac cuccccggca acaaaucucc ccaccgcgac      480

cccgcacccc gcggccccgc ccgcuuccuc ccccuccccg gccuaccccc agcccuaccc      540

gaaccacccg gcauacucgc accccaacca cccgacgucg gcuccuccga cccccuaucc      600

auggucggcg gcucccaagg ccgcuccccc ucauacgaau cuuaaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5351
<211>  2210
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt8)

<400>  5351
gggagaaagc uuaccaugau guggggcacg aaacugcucc caguauugcu cuugcaacac       60

guccuacucc accuucuacu gcuacacguc gcuauacccu augccgaagg acaaaagaaa      120

cgucgcaaca cccuacacga auuuaagaaa agcgccaaga ccacacucac uaaagaagau      180

ccccuacuca aaauaaagac caaaaaggug aacucggcug acgaaugcgc caaccgaugc      240

auccgaaaca gaggcuucac uuuuaccugc aaagccuucg uuuucgacaa gagccgaaaa      300

cgaugcuacu gguacccauu caacagcaug uccuccgggg uaaagaaagg cuucggacau      360

gaguucgauc uauacgaaaa uaaagacuac auaagaaacu gcauaaucgg caaaggaggg      420

uccuacaaag gcacagucag caucacaaag ucagggauca aaugccaacc cuggaacucc      480

augauaccac acgagcacag uuuccucccu aguagcuacc gaggaaaaga ccuccaggag      540

aacuacugcc gcaacccccg cggggaagaa ggcggaccuu ggugcuucac aagcaacccc      600

gagguccgcu acgaggucug cgacaucccc caaugcagcg aagucgagug caugaccugu      660

aacggagaau cauaccgagg cccaauggau cacaccgaau ccggaaaaac augccaacga      720

ugggaccaac aaacaccgca ccgacacaag uuccuccccg aacgguaccc cgacaaagga      780

uucgacgaca acuacugccg caaccccgac ggaaaaccac gaccauggug cuacacgcuc      840

gacccggaca cccccuggga auacugcgcc aucaaaaccu gcgcacacuc agcggugaac      900

gaaaccgaug uaccaaugga aacaaccgaa ugcauccaag gacaaggaga gggcuacagg      960

ggcacgucaa auaccaucug gaacggcaua ccaugccagc gcugggacag ucaguacccc     1020

cacaaacacg acauaacccc cgaaaacuuc aaaugcaaag accucagaga aaacuacugc     1080

cgcaaccccg acggcgccga aucccccugg uguuucacaa ccgacccaaa cauccgcgug     1140

ggcuacugcu cacaaauccc caagugcgac guaucaagcg gccaagacug cuaucgcggg     1200

aacggcaaaa acuacauggg aaaccucuca aagaccagaa gcggccuaac augcucaaug     1260

ugggacaaaa acauggagga ccuccaccgg cacaucuuuu gggaacccga cgcuuccaaa     1320

cucaacaaaa acuacugccg aaaccccgac gacgaugcac acggcccaug gugcuacaca     1380

ggcaaccccc ugauacccug ggacuacugc cccaucucca gaugcgaggg cgacacaaca     1440

ccgaccaucg uaaaucucga ccaccccgua aucuccugcg ccaaaacaaa acaacuaagg     1500

gucgugaacg gaauccccac ccaaacaaca gugggcugga uggucagccu caaauacaga     1560

aacaagcaca ucugcggcgg cucccucauc aaggaaagcu ggguacuaac agccaggcaa     1620

ugcuuccccg ccagaaauaa agaucuaaaa gacuacgaag ccuggcuagg cauccaugac     1680

guccacgaac gcggcgagga gaaacgaaaa caaauucuca acaucucuca acucgucuau     1740

ggaccagaag ggagcgaccu cguucuucug aaacucgccc ggcccgcaau cuuagacaac     1800

uucgucagca caaucgaccu ccccucauac ggaugcacca ucccagaaaa gacaaccugc     1860

agcauauacg gauggggcua caccggccug aucaacgcag acggccuucu cagagucgcc     1920

caucucuaca ucaugggaaa cgaaaaaugc agccaacacc accaaggcaa aguaacgcuc     1980

aacgaauccg aacucugcgc cggagcaggg acuaguuaua agacugacua gcccgauggg     2040

ccucccaacg ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc     2160

cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu                2210


<210>  5352
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt8)

<400>  5352
gggagaaagc uuaccauggg gaaaggggac ccgaaaaagc caagaggaaa gaugucgagc       60

uaugccuuuu ucgugcaaac gugcagggaa gaacacaaga aaaagcaccc ggacgcgagc      120

gugaacuuua gcgaguucuc gaaaaagugc ucagaaaggu ggaagaccau gagcgcgaaa      180

gaaaaaggga aauuugaaga uauggcaaaa gcggacaagg caagguacga gcgagaaaug      240

aagacauaua ucccgccaaa gggcgagaca aagaagaaau ucaaagaccc gaacgcgccc      300

aagcgcccgc caucggccuu uuuccuauuc ugcagcgagu acaggcccaa gauaaagggc      360

gagcacccag gauugagcau aggcgauguc gcgaaaaagc uaggggaaau guggaacaac      420

acggccgcgg acgauaaaca gccguaugaa aagaaagcgg ccaagcucaa ggaaaaguac      480

gagaaagaua ucgcggccua uagagcgaaa ggaaaaccgg acgcggccaa gaaaggggua      540

gugaaagcgg aaaagagcaa gaaaaagaaa gaggaagagg aagaugaaga ggacgaggaa      600

gacgaagagg aagaggaaga ugaagaggac gaggacgagg aagaggacga ugacgaugaa      660

uagggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5353
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt8)

<400>  5353
gggagaaagc uuaccaugaa cuuccuccuc uccugggucc acuggacccu cgcccuccuc       60

cucuaccuuc accacgcaaa auggucccaa gccgccccca ccaccgaagg agaacaaaaa      120

ucccacgaag ucauaaaauu cauggacgua uaccaacgau cauacugccg acccaucgaa      180

acccuagucg acaucuucca agaauaccca gacgaaaucg aauacauauu caaacccucc      240

ugcguacccc ucaugcgcug cgccggcugc ugcaacgacg aagcccuaga augcguccca      300

acaucagaau caaacaucac caugcaaauc augcgcauca aaccacacca aucccaacac      360

auaggcgaaa uguccuuccu ccaacacuca cgcugcgaau gccgccccaa aaaagaccga      420

accaaacccg aaaaaaaauc aguccgaggc aaaggaaaag gccaaaaacg caagcgcaaa      480

aaaucccgcu ucaaauccug guccguccac ugcgaacccu gcuccgaacg ccgaaaacac      540

cucuucgucc aagacccaca aaccugcaaa ugcuccugca aaaacaccga cuccagaugc      600

aaagcacgcc aacucgaacu caacgaaaga accugccgcu gcgacaaacc ccgccgcuaa      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5354
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt9)

<400>  5354
gggagaaagc uuaccaugga cuccgacgaa accggauucg aacacucagg ccucuggguc       60

ucaguccucg ccggccuccu ccucggagcc ugccaagccc acccaauccc cgacuccuca      120

ccacuccucc aauucggcgg ccaaguccga caacgauacc ucuacaccga cgacgcccaa      180

caaaccgaag cccaccucga aauccgcgaa gacggcacag uaggaggcgc cgccgaccaa      240

ucacccgaau cccuacucca acuaaaagca cucaaacccg gcgucaucca aauacucggc      300

gucaaaaccu caagauuccu cugccaacgc cccgacggcg cccucuacgg cucccuccac      360

uucgaccccg aagccugcuc cuuccgcgaa cgccuccucg aagacggcua caacgucuac      420

caauccgaag cccacggccu cccccuccac cucccaggca acaaaucccc acaccgcgac      480

cccgcacccc gcggcccagc ccgcuuccuc ccccuccccg gacuaccccc ugcccuaccc      540

gaaccaccag gcauccucgc accccaacca cccgacgucg gcuccuccga cccccucuca      600

augguaggcg gcucacaagg ccgauccccc uccuacgaau ccuaaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5355
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt9)

<400>  5355
gggagaaagc uuaccaugau guggggcaca aaacuccuuc cgguacugcu gcuacaacac       60

gugcuucucc accuccuucu acuccacguc gcaauccccu augcagaagg gcagaaaaag      120

cgacgcaaca cacuccacga guucaagaaa ucggccaaaa caacccuaac caaagaggac      180

ccccuccuca aaaucaaaac caagaaagua aacuccgccg acgagugcgc caacagaugc      240

auccgcaacc ggggcuucac cuucacaugc aaagccuucg uguucgauaa aagccgcaaa      300

cgaugcuacu gguacccauu caacuccaug agcucgggag uuaagaaagg cuuuggccac      360

gaauuugacc uauacgagaa uaaagacuac auaagaaacu gcaucaucgg uaaaggcggc      420

ucauacaaag ggaccguauc caucacaaaa agcggaauaa aaugccaacc guggaacucu      480

augauacccc acgaacacuc auuccuacca uccucauacc gcggcaaaga ccuacaagag      540

aacuacugcc gaaacccccg aggagaagaa gggggaccau ggugcuucac cucaaaccca      600

gagguacggu acgaagucug cgacauccca caaugcagcg aaguagagug caugaccugu      660

aacggagagu ccuaccgggg accaauggac cauaccgaau cgggaaaaac uugccaacga      720

ugggaucaac aaacacccca ucgucacaaa uuccuaccgg aacgauaccc agacaaagga      780

uucgacgaca acuacugcag aaaucccgac gguaaaccca gaccuuggug cuacacccua      840

gaccccgaca ccccauggga auacugcgcc auaaagaccu gcgcacacuc ugccgucaac      900

gagaccgacg uccccaugga aacaaccgaa ugcauacagg ggcagggaga gggcuaccgc      960

ggcaccagca acaccaucug gaacgguaua cccugccagc gaugggacag ccaauacccc     1020

cacaagcacg acauaacccc ugagaacuuc aagugcaaag accuacgcga aaacuacugc     1080

cgaaacccag acggcgccga aucaccaugg uguuucacaa cagacccaaa cauccgcguc     1140

ggcuacugcu cccaaauacc caaaugcgac gucaguuccg gacaagacug cuaccgaggc     1200

aacggaaaga acuacauggg aaaccucucc aaaacccgua gcgguuuaac augcuccaug     1260

ugggacaaga acauggaaga ccuacacaga cauauauucu gggaacccga cgcaagcaaa     1320

cucaacaaaa auuacugccg caaccccgac gacgaugccc auggccccug gugcuacacc     1380

ggcaaccccc ugauccccug ggacuacugu ccaauaagcc gaugcgaggg ggacaccacc     1440

ccuaccaucg ucaaccugga ccaccccguc aucuccugcg caaaaaccaa acagcuccga     1500

guagugaacg gcaucccaac ccagacaacg gucggaugga uggucucacu aaaauaccga     1560

aacaaacaca uaugcggugg aucccucauc aaagaaagcu gggucuuaac cgcccgccaa     1620

ugcuuccccg cacgaaacaa agaccuaaaa gacuacgaag cauggcuagg cauccacgac     1680

guacacgaac gaggcgaaga aaaacgaaag caaauccuca acaucucaca guuagucuac     1740

ggaccagaag guucagaccu cgugcuccua aaguuagccc gccccgccau acuagacaac     1800

uucgucagca ccaucgaccu accaucauac ggaugcacca uaccagagaa aaccacaugc     1860

aguaucuacg gcuggggcua cacgggccuc aucaacgccg acggccuccu acgcguagcc     1920

caccucuaua ucaugggcaa cgaaaaaugc ucacaacacc accaagggaa aguaacacug     1980

aacgaauccg agcucugcgc cggcgccgag aaaaucggau ccggccccug cgaaggagac     2040

uacgggggac cacuaauaug cgaacagcac aagaugcgaa ugguccucgg agucaucgua     2100

cccggccgag gcugcgcaau acccaaucgc cccggcauau ucguucgcgu agccuacuac     2160

gcuaaaugga uccacaaagu cauacucacc uacaaacuau aaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5356
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt9)

<400>  5356
gggagaaagc uuaccauggg gaaaggggac ccgaagaaac caaggggaaa aaugucgagc       60

uaugccuucu ucgugcaaac gugcagggag gaacacaaga aaaagcaccc agacgcgagc      120

gugaacuuua gcgaguucuc gaaaaagugc ucggaaaggu ggaagacaau gagcgcgaaa      180

gagaaaggga aauuugaaga uauggcgaaa gcggacaagg ccagguacga gcgagagaug      240

aagaccuaua ucccgcccaa gggcgagaca aagaagaaau ucaaagaccc gaacgcgcca      300

aagcgcccgc ccucggcauu uuucuuguuc uguagcgagu acaggccaaa gaucaagggc      360

gagcacccag gcuugagcau aggcgauguc gccaaaaagc ucggggaaau guggaauaac      420

acagcagcag acgauaaaca gcccuaugaa aagaaagcgg caaagcucaa ggaaaaguac      480

gagaaagaua ucgcggccua ucgcgcgaaa gggaaaccgg acgcggcaaa gaaagggguc      540

gugaaagcgg aaaagagcaa gaaaaagaaa gaggaagagg aagaugaaga ggacgaggaa      600

gaugaagagg aagaggaaga ugaagaggac gaggacgaag aagaggacga ugacgaugaa      660

uagggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5357
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt9)

<400>  5357
gggagaaagc uuaccaugaa cuuccuccuc uccugggucc acuggacacu cgcccuccuc       60

cuauaccuac accacgccaa auggagccaa gccgccccca caaccgaagg cgaacaaaaa      120

ucccacgaag ucaucaaauu cauggacguc uaccaacgcu ccuacugccg ccccaucgaa      180

acccucgucg acaucuucca agaauacccc gacgaaaucg aauacaucuu caaacccucc      240

ugcguccccc ucaugcgcug cgccggcugc ugcaacgacg aagcccucga augcgucccc      300

accucagaau caaacauaac aaugcaaauc augcgcauca aaccccacca aucccaacac      360

aucggagaaa uguccuuccu ccaacacuca cgcugcgaau gccgcccaaa aaaagaccgc      420

accaaacccg aaaaaaaauc cguacgcggc aaaggcaaag gccaaaaacg caaacgcaaa      480

aaaucccgcu ucaaaucaug gucaguccac ugcgaacccu gcagcgaacg acgcaaacac      540

cucuucgucc aagacccaca aacaugcaaa ugcuccugca aaaacacaga cucgcgcugc      600

aaagcccgcc aacucgaacu aaacgaacgc accugccgcu gcgacaaacc ccgacgcuag      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5358
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) 
       (opt11)

<400>  5358
gggagaaagc uuaccaugga cuccgacgaa accggcuucg aacacuccgg ccucuggguc       60

uccguccucg ccggccuccu ccuaggcgca ugccaagccc accccauacc cgacuccuca      120

ccccuccucc aauucggcgg ccaaguccgc caacgcuacc uauacaccga cgacgcccaa      180

caaacagaag cccaccucga aauccgagaa gacggcacag ucggcggcgc cgccgaccaa      240

agccccgaau cccuccucca acucaaagcc cucaaacccg gcgucaucca aauccucggc      300

gucaaaacau cccgcuuccu augccaacgc cccgacggcg cccucuacgg cucacuccac      360

uucgaccccg aagccugcuc cuuccgcgaa cgccuccucg aagacggcua caacgucuac      420

caauccgaag cccacggccu accccuacac cuccccggca acaaaucccc ucaccgcgac      480

cccgcacccc gcggccccgc ccgcuuccua ccccuccccg gccucccccc cgcccuaccc      540

gaaccccccg gcauccucgc cccccaaccc ccagacgucg gcuccucuga cccccucucc      600

auggucggcg gcucccaagg ccgcucaccc uccuacgaau ccuaaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5359
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt11)

<400>  5359
gggagaaagc uuaccaugau guggggaaca aaauuacuac caguccuacu acuccaacac       60

guccuacucc accuacuacu acuccacguc gcaauccccu acgccgaagg acagaaaaag      120

cgaagaaaca cacuacacga auuuaagaaa ucagccaaaa ccacccuaac caaagaagac      180

ccccuacuga aaaucaaaac uaagaaaguc aacuccgcag augagugcgc aaaccgaugc      240

auacgcaacc gcggcuucac auucacuugc aaagccuucg uuuucgacaa aucacgaaaa      300

cgcugcuacu gguaccccuu uaacucgaug agcucaggcg ugaagaaagg cuucggccau      360

gaguucgacc uauacgaaaa uaaagauuac auacguaacu gcaucaucgg aaaagguggc      420

agcuacaaag gcacugucuc aauaacgaaa aguggcauca aaugccaacc cuggaacucc      480

augaucccuc acgaacacuc auuccucccc uccagcuaca gagggaaaga ccuacaagaa      540

aacuacugcc guaauccaag aggagaagaa ggcggaccuu ggugcuucac cuccaacccc      600

gaaguaagau acgaagugug cgacauacca caaugcuccg aagucgaaug caugaccugc      660

aacggcgaau ccuaccgagg acccauggac cacaccgaau cagguaagac cugccaacgc      720

ugggaccaac aaacacccca cagacacaaa uuccucccug aacgcuaccc cgacaaaggc      780

uucgacgaca acuacugcag gaacccagac gguaaacccc gacccuggug uuacacccuc      840

gacccagaua cacccuggga auacugcgcc auaaaaacau gcgcacacuc cgccgucaac      900

gagacagacg uccccaugga aaccaccgag ugcauacaag gacaagggga aggauacaga      960

ggaacaucaa acaccauuug gaacggcaua cccugccaaa gaugggacuc ccaguauccc     1020

cacaaacacg acaucacacc agaaaacuuc aaaugcaagg accuacgaga aaacuacugc     1080

cgcaacccag acggagcuga aucccccugg ugcuucacaa cagacccgaa uauccgcguc     1140

ggauacuguu cgcaaauccc aaagugcgac gucagcucag gacaagacug cuacagagga     1200

aacggcaaga acuauauggg caaccuuucg aaaacacgca gcggccuaac cugcuccaug     1260

ugggacaaga acauggaaga ccuccaccgg cacauauucu gggaacccga cgcaaguaaa     1320

cuuaacaaaa acuacugucg caauccggac gacgacgccc acggcccuug gugcuacacc     1380

gguaaccccc uaaucccgug ggacuacugc cccauauccc gaugcgaagg agauacaaca     1440

cccaccaucg ugaaccuaga ccaccccguc aucucaugcg cuaaaacgaa acagcuccga     1500

gucgucaacg gcaucccaac gcaaacgacc gucggaugga uggucucccu gaaauaccgc     1560

aacaaacaca uaugcggcgg aagccuaaua aaagaaagcu ggguccuuac agcccggcaa     1620

ugcuucccag cccguaacaa agaccucaaa gacuacgaag ccuggcucgg cauccacgac     1680

guacaugaac gaggggaaga aaaacgcaaa caaauacuca acaucuccca gcugguauac     1740

ggcccggaag gaagcgaccu cguccucuug aaacuagcca gacccgccau acuagacaac     1800

uucgucagca ccaucgaccu ccccucauac ggcugcacca ucccagaaaa gacaaccugc     1860

ucaaucuacg gcuggggcua caccggacua aucaacgccg acggacuccu gcgggucgcc     1920

cauuuguaca ucaugggaaa cgaaaaaugc ucccaacacc accaaggcaa agucacccug     1980

aacgaauccg aacucugcgc aggcgccgag aaaaucggau caggacccug cgaaggggac     2040

uacgggggcc cccucaucug cgagcaacau aaaaugcgua uggugcuagg cgugaucguc     2100

cccggacgcg gaugcgccau cccgaaccgc cccgggaucu ucguccgcgu cgccuacuac     2160

gccaaaugga uacauaaagu cauucucacc uacaagcugu aaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5360
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt11)

<400>  5360
gggagaaagc uuaccauggg gaaaggggac ccgaaaaagc cgaggggaaa gaugucgagc       60

uaugccuucu ucgugcaaac gugcagggag gaacacaaga aaaagcaccc ggacgcgagc      120

gugaacuuca gcgaguucuc gaaaaagugc ucggaaaggu ggaagaccau gagcgcgaaa      180

gagaaaggga aauuugaaga uauggcgaaa gcggacaagg caagguacga gcgagagaug      240

aagacauaua uaccaccaaa gggcgagacc aagaaaaagu ucaaggaccc gaacgcgccc      300

aagcgcccgc caucggccuu uuucuuguuc uguagcgagu acaggcccaa gaucaaggga      360

gagcacccgg gcuugagcau aggcgacguc gcgaaaaagc ucggggaaau guggaauaac      420

acggccgcgg acgauaaaca gccauaugaa aagaaagcgg ccaagcuaaa ggaaaaguac      480

gagaaagaua ucgcggcaua ucgcgcgaaa gggaaaccgg acgcggccaa gaaaggaguc      540

guaaaagcgg aaaagagcaa gaaaaagaaa gaggaagagg aagaugaaga ggacgaggaa      600

gaugaagagg aagaggaaga ugaagaggac gaggacgagg aagaggacga ugacgaugaa      660

uagggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5361
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt11)

<400>  5361
gggagaaagc uuaccaugaa cuuccuccua uccugggucc acuggacacu cgcccuccuc       60

cucuaccucc accacgccaa auggucccaa gcagcaccca ccacagaagg cgaacaaaaa      120

ucccacgaag ucaucaaguu cauggacguc uaccaacgcu cauacugccg ccccaucgaa      180

acacucguag acaucuucca agaauacccc gacgaaaucg aauacaucuu caaacccucc      240

ugcgucccac uaaugcgcug cgccggaugc ugcaacgacg aagcccucga augcguccca      300

accuccgaau ccaacaucac caugcaaauc augcgcauca aaccccacca aucccaacac      360

aucggcgaaa uguccuuccu ccaacacucc cgcugcgaau gccgccccaa aaaagaccgc      420

accaaacccg aaaaaaaauc aguccgcggc aaaggcaaag gucaaaaacg aaaacgcaaa      480

aaaucacgcu ucaaauccug guccguccac ugcgaacccu gcucagaacg acgcaaacac      540

cucuucgucc aagaccccca aaccugcaaa ugcucaugca aaaacaccga cucccgaugc      600

aaagcccgcc aacucgaacu caacgaacga accugccgcu gcgacaaacc ccgacgcuaa      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5362
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) 
       (opt12)

<400>  5362
gggagaaagc uuaccaugga cucugacgaa acagguuucg aacacucagg acuauggguc       60

ucaguauuag caggacuauu auuaggagca ugucaagcac auccaauacc agacucauca      120

ccacuacuac aauucggcgg acaaguaaga caaagauacu uauacacaga cgaugcacaa      180

caaacagaag cacauuuaga aauaagagaa gauggcacag uaggcggagc agcagaccaa      240

ucaccagaau cacuauuaca auuaaaagca uuaaaaccag gaguaauaca aauauuagga      300

guaaaaacau caagauucuu augucaaaga ccugacggag cacuauacgg aucacuacac      360

uuugacccag aagcaugcuc auuuagagaa agauuauuag aagacggaua caauguauau      420

caaucagaag cacacggauu accauuacac uuacccggaa auaaaucacc acauagagac      480

ccagcaccaa gaggaccugc aagauuucua ccucuaccag gacuaccacc agcacuaccu      540

gaaccaccag gaauauuagc accacaacca ccagacguag gauccucaga ccccuuauca      600

augguaggcg gaucacaagg aagaucacca ucauaugaau cauaaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5363
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt12)

<400>  5363
gggagaaagc uuaccaugau guggggaacu aaauuacuac caguucuauu acuucaacac       60

guccuauuac auuuauuacu auuacacguu gcaauaccau augcagaagg acaaaaaaaa      120

agaaggaaca ccuuacacga auuuaaaaaa ucggcaaaaa caacccucac aaaggaagac      180

ccacuauuaa aaaucaaaac aaaaaaagug aauagugcag acgaaugugc aaauagaugc      240

auaagaaaca gaggauuuac auucacuugu aaagcauuug uauuugauaa aucaaggaaa      300

agguguuauu gguauccuuu uaacucaaug ucuaguggag uaaaaaaagg auucggacau      360

gaauuugacc uauaugaaaa uaaagacuau auaagaaauu gcauaauagg aaaaggugga      420

ucauauaaag ggacaguuag cauaaccaaa ucaggcauaa aaugucaacc auggaauuca      480

augauaccac augaacauuc cuuucuaccu aguaguuauc guggaaaaga uuuacaagaa      540

aauuauugua gaaacccaag aggagaagaa ggagggccau ggugcuuuac aagcaaccca      600

gaagucagau augaaguaug ugacauacca caauguucag aaguagaaug uaugacaugc      660

aauggagaau cguauagagg uccaauggac cauacagaau caggaaaaac augucaaaga      720

ugggaucaac aaaccccaca ucgacauaaa uucuuaccag aacgauaucc agacaaaggg      780

uucgacgaua auuauugcag aaauccagau gggaaaccaa gacccuggug uuacacucua      840

gaccccgaua caccauggga auauugugca auaaaaacau gcgcacacuc agcaguaaau      900

gagacugaug ucccaaugga aacuacagaa ugcauucaag gacaagguga agguuaccga      960

ggcacaagua auacuauaug gaaugggaua ccaugucaaa gaugggacag ucaauaccca     1020

cauaaacaug auauaacgcc agaaaauuuu aaauguaaag auuuaagaga aaauuauugc     1080

agaaauccug auggcgcgga aaguccaugg ugcuucacaa cugauccuaa cauaagaguu     1140

gguuauugca gucaaauacc uaaaugcgau guaucauccg gacaagauug uuauaggggu     1200

aauggaaaaa auuauauggg caauuuauca aaaacacgua guggauuaac auguucaaug     1260

ugggauaaaa auauggaaga uuuacaucga cacauuuucu gggaacccga ugcuaguaaa     1320

uuaaacaaaa acuauugucg aaacccagau gaugaugcac auggaccaug gugcuauaca     1380

gguaacccac uuauaccaug ggacuauugu ccuauaucaa gaugugaagg cgauacaaca     1440

ccuacuauag ucaauuuaga ucauccugua aucaguugcg cuaaaacaaa acaauuaaga     1500

guuguaaacg gaauuccaac acaaacaaca guaggaugga ugguaucacu caaauaccga     1560

aauaaacaca uaugcggagg uucuuuaaua aaagaaagcu ggguauuaac cgcaagacaa     1620

ugcuucccgg caagaaauaa agauuuaaaa gauuaugaag caugguuagg aauacacgau     1680

guacacgaaa ggggagaaga aaaaagaaaa caaauacuaa auauaucaca auuaguauac     1740

ggcccagaag ggagcgaucu aguucuucua aaauuagcca gaccagcaau auuagauaau     1800

uuuguaucua cuaucgaucu accaucauau ggauguacaa uaccugagaa aacaacaugu     1860

ucaauauaug gauggggaua uacuggauua auaaacgccg auggacuucu uagaguagca     1920

cacuuauaua uaaugggaaa cgaaaaaugc ucacaacauc aucaaggaaa aguuacacua     1980

aacgaaucag aacuaugugc uggcgcagaa aaaaucggau caggcccaug cgaaggugau     2040

uacggcggac cacuuauaug ugaacaacau aaaaugcgca ugguauuagg agucauaguu     2100

cccggucggg gcugugcgau accaaacaga ccaggcauau uuguccgugu agccuacuau     2160

gcaaaaugga uacauaaagu aauauuaaca uauaaauuau aaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5364
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt12)

<400>  5364
gggagaaagc uuaccauggg aaaaggagac ccaaaaaaac caagaggaaa aaugucaagc       60

uacgcauucu ucguacaaac augcagagaa gaacacaaaa aaaaacaccc agacgcaagc      120

guaaacuuca gcgaauucag caaaaaaugc ucagaaaggu ggaaaacaau gagcgcaaaa      180

gagaaaggaa aauucgaaga cauggcaaaa gcagacaaag caagauacga aagagaaaug      240

aaaacauaca uaccaccaaa aggagaaaca aaaaaaaaau uuaaagaccc aaacgcacca      300

aaaagaccac caucagcauu cuuccuauuc ugcagugaau acagaccaaa aauaaaagga      360

gaacacccag gacuaagcau aggagacgua gcaaaaaaau uaggagaaau guggaacaac      420

acagcagcag acgacaaaca accauacgaa aaaaaagcag caaaauuaaa agaaaaauac      480

gaaaaggaca uagcagcaua ucgagcaaaa ggaaaaccag acgcagcaaa aaaaggagua      540

guaaaagcag aaaaaagcaa aaaaaaaaaa gaagaagaag aagacgaaga agacgaagaa      600

gacgaagaag aagaagaaga cgaagaagac gaagacgaag aagaagacga cgacgacgaa      660

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5365
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt12)

<400>  5365
gggagaaagc uuaccaugaa cuuccuacua ucauggguac acuggacacu agcauuacua       60

cuauacuuac accacgcaaa auggucacaa gcagcaccaa caacagaagg agaacaaaaa      120

ucacacgaag uaauaaaauu cauggacgua uaccaacgau cauacugcag accaauagaa      180

acacuaguag acauauucca agaauaccca gacgaaauag aauacauauu caaaccauca      240

ugcguaccau uaaugagaug cgcaggaugc ugcaacgacg aagcauuaga augcguacca      300

acaucagaau caaacauaac aaugcaaaua augagaauaa aaccacacca aucacaacac      360

auaggagaaa ugucauuccu acaacauuca agaugcgaau gcagaccaaa aaaagacaga      420

acaaaaccag aaaaaaaauc aguaagagga aaaggaaaag gacaaaaaag aaaaagaaaa      480

aaaucaagau ucaaaucaug gucaguacac ugcgaaccau gcucagaacg aagaaaacac      540

uuauuuguac aagacccaca aacaugcaaa ugcucaugca aaaacacaga cucaagaugc      600

aaagcaagac aacuagaacu aaaugaaaga acaugcagau gugacaaacc aagacgauaa      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5366
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) 
       (opt13)

<400>  5366
gggagaaagc uuaccaugga cucagacgaa acaggauuug aacacucagg acuaugggua       60

ucaguacuag caggauuauu acuaggagcc ugccaagcac acccaauacc agacucauca      120

ccauuauuac aauucggagg acaaguuaga caaagauauc uauauacaga ugacgcacaa      180

caaacagaag cacacuuaga aauaagagaa gacggaacag uaggaggagc agcagaccaa      240

ucaccagaau cccuacuaca auuaaaagca cuaaaaccag gaguaauaca aauauuagga      300

guaaaaacau caagauuccu augccaaaga ccagacggag cacuauacgg cucacuacac      360

uuugacccag aagcaugcuc auucagagaa agacuacuag aagacggaua uaauguauau      420

caaucagaag cacacggacu accuuuacau uuaccaggaa acaaaucacc acacagagac      480

ccagcaccaa gaggcccagc acgcuuuuua ccauuaccag gacuaccacc agcauuacca      540

gaaccaccag gaauacuagc accacaacca ccagauguug gaagcucaga cccacuauca      600

augguaggag gaucacaagg aagaucacca ucauaugaau cauaaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5367
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt13)

<400>  5367
gggagaaagc uuaccaugau guggggaaca aaacuuuuac cuguucuauu auuacaacac       60

guccuguuac acuuauuauu acuacaugua gccauaccuu acgcagaagg acaaaagaaa      120

cgaagaaaca cacuucauga auuuaagaaa uccgcaaaaa caacauuaac aaaagaagau      180

ccauuauuaa aaauaaaaac aaagaaaguu aauucagcag augaaugugc aaauagaugu      240

auaagaaaca gaggauuuac cuuuacaugu aaagcauuug uauucgacaa aucaaggaaa      300

cgauguuacu gguauccauu caauaguaug aguucuggag uaaagaaagg auucggucau      360

gaguucgacc uauaugaaaa uaaagacuau auuagaaauu guauaaucgg caaagguggg      420

ucuuauaaag gcacuguuag uauaacaaaa ucaggaauaa aaugucaacc auggaauagc      480

augauaccac acgaacacuc auuucuccca ucuucauaca ggggcaaaga ccuacaagaa      540

aauuauugua gaaacccaag gggagaagaa ggaggcccau gguguuuuac aucgaauccu      600

gaaguacgau augaaguaug ugacaucccc caaugcagug aaguagaaug uaugacuugu      660

aauggugaau cauaccgagg accuauggac cauacagaau caggaaaaac uugccaacga      720

ugggaucaac aaaccccuca ucgacacaaa uuuuuaccag aacguuaccc agauaaagga      780

uuugacgaua auuacuguag aaauccagac gguaaaccuc gacccuggug uuacacucuu      840

gauccagaua caccauggga auauugcgca auaaaaacuu gcgcacauuc ugcaguaaau      900

gaaacagacg uuccaaugga aacuaccgaa uguauacaag gccaaggaga aggcuauaga      960

gguacaucaa auacaauaug gaauggcaua cccugccaaa ggugggacuc ucaauaucca     1020

cauaaacaug auauaacacc agaaaacuuu aaauguaaag auuuaagaga aaauuacugu     1080

agaaauccgg auggagcaga aucucccugg uguuucacua ccgauccuaa cauaagagua     1140

ggauauugua gccaaauacc uaaaugugau guuagcucag gucaagacug cuacagaggu     1200

aauggcaaaa auuacauggg gaaucucagu aaaacacgua guggacucac auguucaaug     1260

ugggauaaaa auauggaaga ccugcacaga cauauauucu gggaaccuga ugcuucaaaa     1320

uuaaauaaaa auuauugcag aaauccagau gaugacgcuc acggaccaug guguuacacu     1380

gguaauccau uaauaccaug ggauuauugu ccaauaucaa gaugcgaagg ugauacaacu     1440

ccaacaauag uaaaucuaga ucauccagua auauccugug caaaaacaaa acaacuaaga     1500

guaguaaacg gaauaccaac acaaacaaca guaggaugga ugguuaguuu aaaauacaga     1560

aauaaacaua uauguggagg auccuuaaua aaagaaucau ggguauuaac ugcaagacaa     1620

uguuucccag caaggaacaa agauuuaaaa gauuacgaag cauggcuagg aauacaugau     1680

guucacgaaa gaggagaaga aaaacguaaa caaauuuuga acauuucaca acuuguauac     1740

ggcccagaag gaucugauuu aguauuauua aaguuagcaa gaccagcaau ucucgauaau     1800

uucguaucaa cgauagaucu ccccaguuac ggcuguacga uaccagaaaa gacaacaugc     1860

aguauauacg gauggggaua uacaggacua aucaacgcag auggacuuuu aagaguagcc     1920

cacuuauaua uaauggguaa cgaaaaaugu ucacaacauc aucaaggaaa aguaacacua     1980

aaugaaagcg aauuaugugc aggcgcagag aaaauaggaa gcggaccuug ugaaggcgau     2040

uacgguggac cacuaauaug ugaacaacau aaaaugagaa ugguauuagg aguaauaguu     2100

ccaggacgug gaugugccau accaaaccga ccaggaauau uuguuagggu agccuacuac     2160

gcaaaaugga uucacaaagu aauauuaaca uauaaacuau aaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5368
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt13)

<400>  5368
gggagaaagc uuaccauggg aaaaggagac ccaaaaaaac cgagaggaaa aaugagcagc       60

uacgcauuuu ucguacaaac augcagagaa gaacacaaaa aaaaacaccc agacgcaagc      120

guaaacuuua gcgaauuuuc aaaaaaaugc ucagaaagau ggaaaacaau gagcgcaaaa      180

gaaaaaggaa aauucgaaga cauggcgaaa gcagacaaag caagauauga aagagaaaug      240

aaaacauaca uaccaccaaa aggagaaacc aaaaaaaaau uuaaagaccc aaacgcacca      300

aaaagaccac caagcgcauu cuuucuauuc ugcagugaau acagaccaaa aauaaaagga      360

gaacacccag gauuaagcau aggagacgua gcaaaaaaac uaggagaaau guggaacaac      420

acagcagcag acgacaaaca accauacgaa aaaaaagcag caaaacuaaa agaaaaauac      480

gaaaaagaca uagcagcaua uagagcaaaa ggaaaaccag acgcagcaaa aaaaggagua      540

guaaaagcag aaaaaagcaa aaaaaaaaaa gaagaagaag aagacgaaga agacgaagaa      600

gacgaagaag aagaagaaga cgaagaagac gaagacgaag aagaagacga cgacgacgaa      660

uaaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5369
<211>  862
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt13)

<400>  5369
gggagaaagc uuaccaugaa cuuccuacua ucauggguac acuggacacu agcacuacua       60

cuauacuuac accacgcaaa auggagucaa gcagcaccaa caacagaagg agaacaaaaa      120

agccacgaag uaauaaaauu cauggacgua uaucaacgau cauacugcag accaauagaa      180

acacuaguag auaucuucca agaauaccca gacgaaauag aauacauauu caaaccauca      240

ugcguaccau uaaugagaug cgcaggaugc ugcaacgacg aagcacuaga augcguacca      300

acaucagaau caaacauaac aaugcaaaua augagaauaa aaccccacca aagccaacac      360

auaggagaaa ugucauuccu acaacacuca agaugcgaau gcagacccaa aaaagaccga      420

acaaaaccag aaaaaaaauc aguaagagga aaaggaaaag gacaaaaaag aaaacgaaaa      480

aaaucacgau ucaaaucaug gucaguacac ugcgaaccau gcucugaaag aagaaaacac      540

cuauucguac aagacccaca aacauguaaa ugcagcugca aaaacacaga cucaagaugc      600

aaagcaagac aacuagaauu aaacgaaaga acaugcagau gcgacaaacc acgaagauaa      660

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      840

ucuuuucaga gccaccagaa uu                                               862


<210>  5370
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (wt)

<400>  5370
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

cggacgagac cggguucgag cacucaggac uguggguuuc ugugcuggcu ggucuucugc      120

ugggagccug ccaggcacac cccaucccug acuccagucc ucuccugcaa uucgggggcc      180

aaguccggca gcgguaccuc uacacagaug augcccagca gacagaagcc caccuggaga      240

ucagggagga ugggacggug gggggcgcug cugaccagag ccccgaaagu cuccugcagc      300

ugaaagccuu gaagccggga guuauucaaa ucuugggagu caagacaucc agguuccugu      360

gccagcggcc agauggggcc cuguauggau cgcuccacuu ugacccugag gccugcagcu      420

uccgggagcg gcuucuugag gacggauaca auguuuacca guccgaagcc cacggccucc      480

cgcugcaccu gccagggaac aaguccccac accgggaccc ugcaccccga ggaccagcuc      540

gcuuccugcc acuaccaggc cugccccccg cacucccgga gccacccgga auccuggccc      600

cccagccccc cgaugugggc uccucggacc cucugagcau ggugggaggu ucccagggcc      660

gaagccccag cuacgagucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5371
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (wt)

<400>  5371
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

cggacgagac cggguucgag cacucaggac uguggguuuc ugugcuggcu ggucuucugc      120

ugggagccug ccaggcacac cccaucccug acuccagucc ucuccugcaa uucgggggcc      180

aaguccggca gcgguaccuc uacacagaug augcccagca gacagaagcc caccuggaga      240

ucagggagga ugggacggug gggggcgcug cugaccagag ccccgaaagu cuccugcagc      300

ugaaagccuu gaagccggga guuauucaaa ucuugggagu caagacaucc agguuccugu      360

gccagcggcc agauggggcc cuguauggau cgcuccacuu ugacccugag gccugcagcu      420

uccgggagcg gcuucuugag gacggauaca auguuuacca guccgaagcc cacggccucc      480

cgcugcaccu cccagggaac aaguccccac accgggaccc ugcaccccga ggaccagcuc      540

gcuuccugcc acuaccaggc cugccccccg cacucccgga gccacccgga auccuggccc      600

cccagccccc cgaugugggc uccucggacc cucugagcau ggugggaggu ucccagggcc      660

gaagccccag cuacgagucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5372
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (wt)

<400>  5372
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

gggggaccaa acuucugccg guccuguugc ugcagcaugu ccuccugcac cuccuccugc      120

uucaugucgc cauccccuau gcagaaggac agaagaaaag aagaaauaca cuucaugaau      180

uuaaaaaguc agcaaaaacu acucuuacca aggaagaccc auuacugaag auuaaaacca      240

aaaaagugaa cucugcagau gagugugcca acagguguau caggaacagg ggcuuuacgu      300

ucacuugcaa ggccuucguu uuugauaagu caagaaaacg augcuacugg uauccuuuca      360

auaguauguc aaguggagug aaaaaagggu uuggccauga auuugaccuc uaugaaaaca      420

aagacuauau uagaaacugc aucauuggua aaggaggcag cuauaaaggg acgguaucca      480

ucacuaagag uggcaucaaa ugccagccuu ggaauuccau gaucccccau gaacacagcu      540

uuuugccuuc gagcuaucgc gguaaagacc uacaggaaaa cuacugucga aauccucgag      600

gggaagaagg gggacccugg uguuucacaa gcaauccaga gguacgcuac gaagucugug      660

acauuccuca guguucagaa guugaaugca ugaccugcaa uggugaaagc uacagagguc      720

ccauggauca cacagaauca ggcaagacuu gucagcgcug ggaccagcag acaccacacc      780

ggcacaaguu cuugccagaa agauaucccg acaagggcuu ugaugauaau uauugccgca      840

auccugaugg caagccgagg ccauggugcu acacucuuga cccugacacc ccuugggagu      900

auugugcaau uaaaacgugc gcucacagug cugugaauga gacugauguc ccuauggaaa      960

caacugaaug cauucaaggc caaggagaag guuacagggg aaccagcaau accauuugga     1020

auggaauucc cugucagcgu ugggauucgc aguacccuca caagcaugau aucacucccg     1080

agaacuucaa augcaaggac cuuagagaaa auuauugccg caauccagau ggggcugaau     1140

caccauggug uuuuaccacu gacccaaaca uccgaguugg cuacugcucu caaauuccca     1200

agugugacgu gucaagugga caagauuguu aucguggcaa ugggaaaaau uacaugggca     1260

acuuauccaa aacaaggucu ggacuuacau guuccaugug ggacaagaau auggaggauu     1320

uacaccguca uaucuucugg gagccagaug cuagcaaauu gaauaagaau uacugccgga     1380

auccugauga ugaugcccau ggaccuuggu gcuacacggg gaauccucuu auuccuuggg     1440

auuauugccc uauuucccgu ugugaaggag auacuacacc uacaauuguc aauuuggacc     1500

auccuguaau auccugugcc aaaacaaaac aacugcgggu uguaaauggc auuccaacac     1560

aaacaacagu aggguggaug guuaguuuga aauacagaaa uaaacauauc uguggaggau     1620

cauugauaaa ggaaaguugg guucuuacug caagacaaug uuuuccagcc agaaacaaag     1680

acuugaaaga cuaugaagcu uggcuuggca uccacgaugu ucaugagaga ggcgaggaga     1740

agcgcaagca gaucuuaaac auuucccagc uggucuaugg uccugaaggc ucagacuugg     1800

uuuuacugaa gcuugcucga ccugcaaucc uggauaacuu ugucaguaca auugauuuac     1860

cuaguuaugg uuguacaauc ccugaaaaga ccacuugcag uauuuacggc uggggcuaca     1920

cuggauugau caacgcggau gguuuauuac gaguagcuca ucuguauauu auggggaaug     1980

agaaaugcag ucagcaccau caaggcaagg ugacuuugaa ugagucugag uuaugugcug     2040

gggcugaaaa gauuggauca ggaccaugug agggagauua ugguggccca cucauuugug     2100

aacaacacaa aaugagaaug guucuuggug ucauuguucc uggucgugga ugugccaucc     2160

caaaucgucc ugguauuuuu guucgaguag cauauuaugc aaaauggaua cacaaaguaa     2220

uuuugacaua caaguuguaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5373
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (wt)

<400>  5373
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

gggggaccaa acuucugccg guccuguugc ugcagcaugu ccuccugcac cuccuccugc      120

uucaugucgc cauccccuau gcagaaggac agaagaaaag aagaaauaca cuucaugaau      180

uuaaaaaguc agcaaaaacu acucuuacca aggaagaccc auuacugaag auuaaaacca      240

aaaaagugaa cucugcagau gagugugcca acagguguau caggaacagg ggcuuuacgu      300

ucacuugcaa ggccuucguu uuugauaagu caagaaaacg augcuacugg uauccuuuca      360

auaguauguc aaguggagug aaaaaagggu uuggccauga auuugaccuc uaugaaaaca      420

aagacuauau uagaaacugc aucauuggua aaggaggcag cuauaaaggg acgguaucca      480

ucacuaagag uggcaucaaa ugccagccuu ggaacuccau gaucccccau gaacacagcu      540

uuuugccuuc gagcuaucgc gguaaagacc uacaggaaaa cuacugucga aauccucgag      600

gggaagaagg gggacccugg uguuucacaa gcaauccaga gguacgcuac gaagucugug      660

acauuccuca guguucagaa guugaaugca ugaccugcaa uggugaaagc uacagagguc      720

ccauggauca cacagaauca ggcaagacuu gucagcgcug ggaccagcag acaccacacc      780

ggcacaaguu cuugccagaa agauaucccg acaagggcuu ugaugauaau uauugccgca      840

auccugaugg caagccgagg ccauggugcu acacucuuga cccugacacc ccuugggagu      900

auugugcaau uaaaacgugc gcucacagug cugugaauga gacugauguc ccuauggaaa      960

caacugaaug cauucaaggc caaggagaag guuacagggg aaccagcaau accauuugga     1020

auggaauccc cugucagcgu ugggauucgc aguacccuca caagcaugau aucacucccg     1080

agaacuucaa augcaaggac cuuagagaaa auuauugccg caauccagau ggggcugaau     1140

caccauggug uuuuaccacu gacccaaaca uccgaguugg cuacugcucu caaauuccca     1200

agugugacgu gucaagugga caagauuguu aucguggcaa ugggaaaaau uacaugggca     1260

acuuauccaa aacaaggucu ggacuuacau guuccaugug ggacaagaau auggaggauu     1320

uacaccguca uaucuucugg gagccagaug cuagcaaauu gaauaagaau uacugccgga     1380

auccugauga ugaugcccau ggaccuuggu gcuacacggg gaauccucuu auuccuuggg     1440

auuauugccc uauuucccgu ugugaaggag auacuacacc uacaauuguc aauuuggacc     1500

auccuguaau auccugugcc aaaacaaaac aacugcgggu uguaaauggc auuccaacac     1560

aaacaacagu aggguggaug guuaguuuga aauacagaaa uaaacauauc uguggaggau     1620

cauugauaaa ggaaaguugg guucuuacug caagacaaug uuuuccagcc agaaacaaag     1680

acuugaaaga cuaugaagca uggcuuggca uccacgaugu ucaugagaga ggcgaggaga     1740

agcgcaagca gaucuuaaac auuucccagc uggucuaugg uccugaaggc ucagacuugg     1800

uuuuacugaa gcuggcucga ccugcaaucc uggauaacuu ugucaguaca auugauuuac     1860

cuaguuaugg uuguacaauc ccugaaaaga ccacuugcag uauuuacggc uggggcuaca     1920

cuggauugau caacgcggau gguuuauuac gaguagcuca ucuguauauu auggggaaug     1980

agaaaugcag ucagcaccau caaggcaagg ugacuuugaa ugagucugag uuaugugcug     2040

gggcugaaaa gauuggauca ggaccaugug agggagauua ugguggccca cucauuugug     2100

aacaacacaa aaugagaaug guucuuggug ucauuguucc uggucgugga ugugccaucc     2160

caaaucgucc ugguauuuuu guucgaguag cauauuaugc aaaauggaua cacaaaguaa     2220

uuuugacaua caaguuguaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5374
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (wt)

<400>  5374
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

aaggagaucc uaagaagccg agaggcaaaa ugucaucaua ugcauuuuuu gugcaaacuu      120

gucgggagga gcauaagaag aagcacccag augcuucagu caacuucuca gaguuuucua      180

agaagugcuc agagaggugg aagaccaugu cugcuaaaga gaaaggaaaa uuugaagaua      240

uggcaaaagc ggacaaggcc cguuaugaaa gagaaaugaa aaccuauauc ccucccaaag      300

gggagacaaa aaagaaguuc aaggauccca augcacccaa gaggccuccu ucggccuucu      360

uccucuucug cucugaguau cgcccaaaaa ucaaaggaga acauccuggc cuguccauug      420

gugauguugc gaagaaacug ggagagaugu ggaauaacac ugcugcagau gacaagcagc      480

cuuaugaaaa gaaggcugcg aagcugaagg aaaaauacga aaaggauauu gcugcauauc      540

gagcuaaagg aaagccugau gcagcaaaaa agggaguugu caaggcugaa aaaagcaaga      600

aaaagaagga agaggaggaa gaugaggaag augaagagga ugaggaggag gaggaagaug      660

aagaagauga agaugaagaa gaagaugaug augaugaaua aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5375
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (wt)

<400>  5375
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uucugcucuc uugggugcac uggacccugg cuuuacugcu guaccuccac caugccaagu      120

ggucccaggc ugcacccacg acagaaggag agcagaaguc ccaugaagug aucaaguuca      180

uggaugucua ccagcgaagc uacugccguc cgauugagac ccugguggac aucuuccagg      240

aguaccccga cgagauagag uacaucuuca agccguccug ugugccgcug augcgcugug      300

caggcugcug uaacgaugaa gcccuggagu gcgugcccac gucagagagc aacaucacca      360

ugcagaucau gcggaucaaa ccucaccaaa gccagcacau aggagagaug agcuuccuac      420

agcacagcag augugaaugc agaccaaaga aagacagaac aaagccagaa aaaaaaucag      480

uucgaggaaa gggaaagggu caaaaacgaa agcgcaagaa aucccgguuu aaauccugga      540

gcguucacug ugagccuugu ucagagcgga gaaagcauuu guuuguccaa gauccgcaga      600

cguguaaaug uuccugcaaa aacacagacu cgcguugcaa ggcgaggcag cuugaguuaa      660

acgaacguac uugcagaugu gacaagccaa ggcggugagg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5376
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt1)

<400>  5376
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcgacgagac cggcuucgag cacuccgggc ugugggugag cguccucgcc ggccugcugc      120

ucggggccug ccaggcccac cccaucccgg acuccagccc ccugcugcag uucggcggcc      180

aggugcgcca gcgguaccuc uacaccgacg acgcccagca gacggaggcc caccuggaga      240

uccgcgagga cgggaccgug ggcggggccg ccgaccaguc ccccgagagc cugcuccagc      300

ugaaggcgcu gaagcccggc gucauccaga uccucggggu gaagaccucc cgguuccugu      360

gccagcgccc ggacggcgcc cuguacggga gccuccacuu cgaccccgag gccugcuccu      420

uccgggagcg ccugcucgag gacggcuaca acguguacca gagcgaggcc cacggccugc      480

cccugcaccu ccccgggaac aaguccccgc accgcgaccc cgcgccccgg ggccccgccc      540

gcuuccugcc gcugcccggg cucccgcccg cccugcccga gccgcccggc auccuggcgc      600

cccagccgcc cgacgucggc agcuccgacc cccucagcau gguggggggc ucccagggcc      660

ggagccccuc cuacgagagc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5377
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt1) R4603

<400>  5377
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

ggggcaccaa gcugcucccc gugcugcugc uccagcacgu ccugcugcac cuccugcugc      120

uccacguggc caucccguac gccgaggggc agaagaagcg ccggaacacc cugcacgagu      180

ucaagaagag cgcgaagacg acccugacca aggaggaccc ccuccugaag aucaagacca      240

agaaggugaa cuccgccgac gagugcgcca accgcugcau ccggaaccgc ggcuucacgu      300

ucaccugcaa ggccuucguc uucgacaaga gccggaagcg cugcuacugg uaccccuuca      360

acuccaugag cuccggggug aagaagggcu ucgggcacga guucgaccug uacgagaaca      420

aggacuacau ccggaacugc aucaucggca agggcgggag cuacaagggc accgugucca      480

ucaccaagag cgggaucaag ugccagcccu ggaacuccau gaucccgcac gagcacagcu      540

uccuccccuc cagcuaccgc ggcaaggacc ugcaggagaa cuacugccgg aacccccgcg      600

gggaggaggg cggccccugg ugcuucacgu ccaacccgga gguccgguac gaggugugcg      660

acauccccca gugcagcgag guggagugca ugaccugcaa cggggagucc uaccgcggcc      720

ccauggacca caccgagagc gggaagaccu gccagcggug ggaccagcag acgccccacc      780

gccacaaguu ccugccggag cgguaccccg acaagggcuu cgacgacaac uacugccgca      840

accccgacgg caagccccgg ccguggugcu acacccucga ccccgacacc cccugggagu      900

acugcgccau caagaccugc gcgcacuccg ccgucaacga gacggacgug cccauggaga      960

ccaccgagug cauccagggg cagggcgagg gguaccgcgg caccagcaac acgaucugga     1020

acgggauccc gugccagcgg ugggacuccc aguaccccca caagcacgac aucacccccg     1080

agaacuucaa gugcaaggac cugcgcgaga acuacugccg gaaccccgac ggcgccgaga     1140

gcccguggug cuucaccacc gaccccaaca uccgcguggg cuacugcagc cagaucccca     1200

agugcgacgu cuccagcggg caggacugcu accgcggcaa cgggaagaac uacaugggca     1260

accuguccaa gacgcggagc gggcucaccu gcuccaugug ggacaagaac auggaggacc     1320

ugcaccgcca caucuucugg gagcccgacg ccagcaagcu gaacaagaac uacugccgga     1380

acccggacga cgacgcgcac ggccccuggu gcuacaccgg caacccccuc aucccguggg     1440

acuacugccc caucucccgc ugcgaggggg acaccacgcc caccaucgug aaccuggacc     1500

accccgugau cagcugcgcc aagaccaagc agcugcgggu cgugaacggc aucccgaccc     1560

agacgaccgu gggguggaug gucucccuca aguaccgcaa caagcacauc ugcggcggga     1620

gccugaucaa ggaguccugg gugcugaccg cccggcagug cuuccccgcc cgcaacaagg     1680

accucaagga cuacgaggcc uggcugggca uccacgacgu gcacgagcgg ggcgaggaga     1740

agcgcaagca gauccugaac aucagccagc ucgucuacgg gcccgagggc uccgaccugg     1800

ugcugcucaa gcuggcgcgg cccgccaucc uggacaacuu cgugagcacc aucgaccucc     1860

cguccuacgg gugcacgauc cccgagaaga ccaccugcag caucuacggc uggggcuaca     1920

ccgggcugau caacgccgac ggccugcucc gcgucgccca ccuguacauc auggggaacg     1980

agaagugcuc ccagcaccac cagggcaagg ugacccugaa cgagagcgag cucugcgccg     2040

gggcggagaa gaucggcucc ggccccugcg agggggacua cggcgggccc cugaucugcg     2100

agcagcacaa gaugcggaug guccugggcg ugaucgugcc ggggcgcggc ugcgccaucc     2160

ccaaccggcc cggcaucuuc guccgcgugg ccuacuacgc caaguggauc cacaagguga     2220

uccugacgua caagcucuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5378
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt1)

<400>  5378
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

agggggaccc caagaagccg cgcggcaaga ugagcagcua cgccuucuuc gugcagaccu      120

gccgggagga gcacaagaag aagcaccccg acgccagcgu caacuucucc gaguucagca      180

agaagugcuc cgagcgcugg aagaccauga gcgcgaagga gaaggggaag uucgaggaca      240

uggccaaggc cgacaaggcc cgguacgagc gcgagaugaa gacguacauc ccgcccaagg      300

gcgagaccaa gaagaaguuc aaggacccca acgcccccaa gcggccgccc uccgcguucu      360

uccuguucug cagcgaguac cgccccaaga ucaaggggga gcaccccggc cucuccaucg      420

gcgacguggc caagaagcug ggggagaugu ggaacaacac cgccgccgac gacaagcagc      480

ccuacgagaa gaaggcggcc aagcugaagg agaaguacga gaaggacauc gccgccuacc      540

gggccaaggg caagcccgac gcggccaaga aggggguggu caaggccgag aaguccaaga      600

agaagaagga ggaggaggag gacgaggagg acgaggagga cgaggaggag gaggaggacg      660

aggaggacga ggacgaggag gaggacgacg acgacgagug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5379
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt1)

<400>  5379
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugcucag cugggugcac uggacccugg cccugcuccu guaccugcac cacgcgaagu      120

ggucgcaggc cgccccgacg accgagggcg agcagaagag ccacgagguc aucaaguuca      180

uggacgugua ccagcggagc uacugccgcc ccaucgagac ccucguggac aucuuccagg      240

aguacccgga cgagaucgag uacaucuuca agccgucgug cgucccccug augcggugcg      300

cggggugcug caacgacgag gcccuggagu gcgugccgac gagcgagagc aacaucacca      360

ugcagaucau gcggaucaag ccgcaccagu cgcagcacau cggcgagaug agcuuccucc      420

agcacagccg cugcgagugc cggcccaaga aggaccggac caagccggag aagaagucgg      480

ugcgcggcaa ggggaagggc cagaagcgga agcggaagaa gagccgcuuc aagagcuggu      540

cgguccacug cgagccgugc agcgagcggc ggaagcaccu guucgugcag gacccccaga      600

cgugcaagug cagcugcaag aacaccgacu cgcgcugcaa ggcccggcag cuggagcuca      660

acgagcggac cugccgcugc gacaagccgc ggcggugagg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5380
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt2)

<400>  5380
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

ccgacgagac cggcuucgag cacuccggcc ucugggucuc cguccucgcc ggccuccucc      120

ucggcgccug ccaggcccac cccauccccg acuccucccc ccuccuccag uucggcggcc      180

agguccgcca gcgcuaccuc uacaccgacg acgcccagca gaccgaggcc caccucgaga      240

uccgcgagga cggcaccguc ggcggcgccg ccgaccaguc ccccgagucc cuccuccagc      300

ucaaggcccu caagcccggc gucauccaga uccucggcgu caagaccucc cgcuuccucu      360

gccagcgccc cgacggcgcc cucuacggcu cccuccacuu cgaccccgag gccugcuccu      420

uccgcgagcg ccuccucgag gacggcuaca acgucuacca guccgaggcc cacggccucc      480

cccuccaccu ccccggcaac aagucccccc accgcgaccc cgccccccgc ggccccgccc      540

gcuuccuccc ccuccccggc cucccccccg cccuccccga gccccccggc auccucgccc      600

cccagccccc cgacgucggc uccuccgacc cccucuccau ggucggcggc ucccagggcc      660

gcucccccuc cuacgagucc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5381
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt2)

<400>  5381
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

ggggcaccaa gcuccucccc guccuccucc uccagcacgu ccuccuccac cuccuccucc      120

uccacgucgc cauccccuac gccgagggcc agaagaagcg ccgcaacacc cuccacgagu      180

ucaagaaguc cgccaagacc acccucacca aggaggaccc ccuccucaag aucaagacca      240

agaaggucaa cuccgccgac gagugcgcca accgcugcau ccgcaaccgc ggcuucaccu      300

ucaccugcaa ggccuucguc uucgacaagu cccgcaagcg cugcuacugg uaccccuuca      360

acuccauguc cuccggcguc aagaagggcu ucggccacga guucgaccuc uacgagaaca      420

aggacuacau ccgcaacugc aucaucggca agggcggcuc cuacaagggc accgucucca      480

ucaccaaguc cggcaucaag ugccagcccu ggaacuccau gaucccccac gagcacuccu      540

uccuccccuc cuccuaccgc ggcaaggacc uccaggagaa cuacugccgc aacccccgcg      600

gcgaggaggg cggccccugg ugcuucaccu ccaaccccga gguccgcuac gaggucugcg      660

acauccccca gugcuccgag gucgagugca ugaccugcaa cggcgagucc uaccgcggcc      720

ccauggacca caccgagucc ggcaagaccu gccagcgcug ggaccagcag accccccacc      780

gccacaaguu ccuccccgag cgcuaccccg acaagggcuu cgacgacaac uacugccgca      840

accccgacgg caagccccgc cccuggugcu acacccucga ccccgacacc cccugggagu      900

acugcgccau caagaccugc gcccacuccg ccgucaacga gaccgacguc cccauggaga      960

ccaccgagug cauccagggc cagggcgagg gcuaccgcgg caccuccaac accaucugga     1020

acggcauccc cugccagcgc ugggacuccc aguaccccca caagcacgac aucacccccg     1080

agaacuucaa gugcaaggac cuccgcgaga acuacugccg caaccccgac ggcgccgagu     1140

cccccuggug cuucaccacc gaccccaaca uccgcgucgg cuacugcucc cagaucccca     1200

agugcgacgu cuccuccggc caggacugcu accgcggcaa cggcaagaac uacaugggca     1260

accucuccaa gacccgcucc ggccucaccu gcuccaugug ggacaagaac auggaggacc     1320

uccaccgcca caucuucugg gagcccgacg ccuccaagcu caacaagaac uacugccgca     1380

accccgacga cgacgcccac ggccccuggu gcuacaccgg caacccccuc auccccuggg     1440

acuacugccc caucucccgc ugcgagggcg acaccacccc caccaucguc aaccucgacc     1500

accccgucau cuccugcgcc aagaccaagc agcuccgcgu cgucaacggc auccccaccc     1560

agaccaccgu cggcuggaug gucucccuca aguaccgcaa caagcacauc ugcggcggcu     1620

cccucaucaa ggaguccugg guccucaccg cccgccagug cuuccccgcc cgcaacaagg     1680

accucaagga cuacgaggcc uggcucggca uccacgacgu ccacgagcgc ggcgaggaga     1740

agcgcaagca gauccucaac aucucccagc ucgucuacgg ccccgagggc uccgaccucg     1800

uccuccucaa gcucgcccgc cccgccaucc ucgacaacuu cgucuccacc aucgaccucc     1860

ccuccuacgg cugcaccauc cccgagaaga ccaccugcuc caucuacggc uggggcuaca     1920

ccggccucau caacgccgac ggccuccucc gcgucgccca ccucuacauc augggcaacg     1980

agaagugcuc ccagcaccac cagggcaagg ucacccucaa cgaguccgag cucugcgccg     2040

gcgccgagaa gaucggcucc ggccccugcg agggcgacua cggcggcccc cucaucugcg     2100

agcagcacaa gaugcgcaug guccucggcg ucaucguccc cggccgcggc ugcgccaucc     2160

ccaaccgccc cggcaucuuc guccgcgucg ccuacuacgc caaguggauc cacaagguca     2220

uccucaccua caagcucuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5382
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt2)

<400>  5382
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

agggcgaccc caagaagccc cgcggcaaga uguccuccua cgccuucuuc guccagaccu      120

gccgcgagga gcacaagaag aagcaccccg acgccuccgu caacuucucc gaguucucca      180

agaagugcuc cgagcgcugg aagaccaugu ccgccaagga gaagggcaag uucgaggaca      240

uggccaaggc cgacaaggcc cgcuacgagc gcgagaugaa gaccuacauc ccccccaagg      300

gcgagaccaa gaagaaguuc aaggacccca acgcccccaa gcgccccccc uccgccuucu      360

uccucuucug cuccgaguac cgccccaaga ucaagggcga gcaccccggc cucuccaucg      420

gcgacgucgc caagaagcuc ggcgagaugu ggaacaacac cgccgccgac gacaagcagc      480

ccuacgagaa gaaggccgcc aagcucaagg agaaguacga gaaggacauc gccgccuacc      540

gcgccaaggg caagcccgac gccgccaaga agggcgucgu caaggccgag aaguccaaga      600

agaagaagga ggaggaggag gacgaggagg acgaggagga cgaggaggag gaggaggacg      660

aggaggacga ggacgaggag gaggacgacg acgacgagug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5383
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt2)

<400>  5383
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuccucuc cuggguccac uggacccucg cccuccuccu cuaccuccac cacgccaagu      120

ggucccaggc cgcccccacc accgagggcg agcagaaguc ccacgagguc aucaaguuca      180

uggacgucua ccagcgcucc uacugccgcc ccaucgagac ccucgucgac aucuuccagg      240

aguaccccga cgagaucgag uacaucuuca agcccuccug cgucccccuc augcgcugcg      300

ccggcugcug caacgacgag gcccucgagu gcguccccac cuccgagucc aacaucacca      360

ugcagaucau gcgcaucaag ccccaccagu cccagcacau cggcgagaug uccuuccucc      420

agcacucccg cugcgagugc cgccccaaga aggaccgcac caagcccgag aagaaguccg      480

uccgcggcaa gggcaagggc cagaagcgca agcgcaagaa gucccgcuuc aaguccuggu      540

ccguccacug cgagcccugc uccgagcgcc gcaagcaccu cuucguccag gacccccaga      600

ccugcaagug cuccugcaag aacaccgacu cccgcugcaa ggcccgccag cucgagcuca      660

acgagcgcac cugccgcugc gacaagcccc gccgcugagg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5384
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt3)

<400>  5384
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcgaugagac cggcuucgaa cacuccgggc uguggguguc uguccucgcc ggacuucugu      120

ugggugcuug ccaggcacau cccaucccug acucaagucc auuacugcaa uuuggcgggc      180

agguuagaca gagguaccua uauacagaug acgcccagca aacugaggcg caccucgaaa      240

uucgggagga uggaacggug ggcggugcug ccgaccagag cccggaaucc cugcuucagc      300

ugaaggcauu gaaacccggg guaauacaga uccucggagu gaagaccucu cgcuuccugu      360

gucaacgacc ugauggcgcc cuguacggcu cgcuccauuu ugacccagag gcuugcucau      420

uccgugagag auuacuggaa gauggguaua acgucuacca gagcgaggca cacggacuuc      480

ccuugcaucu gccugguaau aaaaguccac acagggaccc cgccccucgg ggcccagcuc      540

gcuuucuacc gcuccccggg cugccuccag cccuucccga accuccaggc auucuggcgc      600

cccagccgcc ugauguggga uccucugacc ccuugagcau gguugguggg ucccagggaa      660

gaucaccaag uuaugagagc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5385
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt3)

<400>  5385
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

ggggcaccaa gcugcucccc gugcuucugu ugcagcacgu cuuacugcau cuacuccugc      120

uucacguugc caucccuuac gcugaggggc aaaagaagag aaggaacaca cugcaugagu      180

ucaaaaagag cgcaaaaacu acguugacca aggaggaccc acuccugaag auuaaaacaa      240

agaaaguaaa uuccgccgau gaaugcgcga accgguguau acgcaaucga ggauuuacuu      300

uuaccugcaa ggcuuucgug uucgacaaau cucguaagag auguuauugg uacccguuua      360

acucaaugag uagcggugug aagaaaggcu ucgggcacga guuugaucug uaugaaaaua      420

aggacuacau caggaacugc auuaucggaa aaggcgguuc cuauaagggg acagucucua      480

uuaccaaauc gggaaucaag ugucagcccu ggaacucaau gauaccucau gagcacagcu      540

uccucccaag uuccuaccgg ggcaaagauu uacaggagaa uuauugccgc aaucccagag      600

gcgaagaagg gggaccuugg uguuuuacuu cuaacccaga agugagguac gagguuugcg      660

acauccccca guguagcgag guggaaugca ugacauguaa uggugagucc uaccggggcc      720

cuauggauca caccgaauca gggaagacgu gccaacgcug ggaccagcag acuccacauc      780

gacacaaguu ccugccggag agauaucccg auaaaggauu ugacgauaac uacugcagga      840

auccugacgg caagccacgg cccugguguu auacccuuga uccugacaca ccaugggaau      900

acugcgccau uaaaacuugu gcacauagug ccgucaacga gaccgacgug cccauggaga      960

caaccgaaug cauccagggu caaggggagg gauaucgugg cacgagcaau acuauuugga     1020

acggcauccc gugucagcgc ugggauucuc aguacccuca caagcacgac auaacacccg     1080

aaaacuucaa augcaaggau uugagagaga auuauuguag gaacccagac ggggcugaau     1140

ccccuuggug cuuuaccacu gaucccaaua uucggguagg auacuguuca cagaucccaa     1200

agugcgacgu uagcaguggu caagauuguu accgaggcaa cgggaaaaau uauaugggaa     1260

accugucuaa gacacgcucc ggccuaaccu gcagcaugug ggacaaaaau auggaggauc     1320

uccauagaca cauuuucugg gagcccgacg caucgaagcu gaacaaaaau uacugcagga     1380

acccugauga cgacgcccau gguccauggu guuauacggg gaauccgcuu auccccuggg     1440

auuacugccc uaucucucgg ugugaaggcg acaccacacc aacuauugug aaccuggauc     1500

accccgucau auccugcgcu aagaccaagc aguugcgcgu ggugaaugga aucccuacac     1560

agacuaccgu cggcuggaug guuucacuca aauauagaaa caagcauauu ugugggggaa     1620

gucugaucaa agagagcugg guguuaacag ccaggcaaug cuucccagcg cguaauaagg     1680

accugaaaga uuacgaagca uggcucggua uacacgacgu acacgagcgg ggcgaagaga     1740

agcgaaagca gauucuuaac aucucccagc ugguguaugg gcccgaggga ucugauuugg     1800

uccuacugaa acucgccaga ccggcuaucc uggacaacuu ugugagcacc auugaucuuc     1860

cuucauacgg cuguacuauc ccagaaaaga cgacaugcag uauuuacggu uggggguaua     1920

ccggccugau aaaugccgac ggauugcuca ggguugcaca ucuguacauc augggcaacg     1980

agaaauguuc ccagcaccau caagggaagg ugacuuuaaa ugaaagcgag cugugcgcug     2040

gagccgagaa aauugguucu ggccccugug aaggggauua uggaggcccu cuaaucugcg     2100

agcagcacaa gaugcgcaug guccucggug ugaucguacc cgggcggggc ugcgcgauuc     2160

caaacagacc uggaauauuc guuagggugg ccuacuaugc aaaauggauc cacaagguca     2220

uucugaccua caaacuuuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5386
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt3)

<400>  5386
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

agggggaccc caaaaagccu agaggaaaaa ugagcuccua cgccuucuuu gugcagaccu      120

gcagggagga acacaagaaa aagcauccag augcuucugu caacuucuca gaguuuagua      180

agaaauguag cgaacggugg aagacaaugu ccgcaaaaga gaaggguaaa uucgaagaca      240

uggccaaggc ggauaaggcu cgcuaugagc gagagaugaa aacuuacauc ccgcccaagg      300

gcgaaacgaa aaagaaauuu aaggacccua augccccaaa acgucccccu ucugcauucu      360

uucuguucug cucggaguau agaccaaaga uuaaggggga acaccccgga cucucaauag      420

gcgauguugc caagaaacuu ggugagaugu ggaacaauac cgcugcagac gauaaacaac      480

cuuacgagaa gaaagccgcu aagcugaagg aaaaauauga gaaggacauc gccgcguaca      540

gggcaaaagg gaagccagau gccgcuaaaa agggaguggu aaaggccgag aaaagcaaga      600

aaaagaaaga agaagaggag gacgaagagg augaagagga cgaagaggag gaagaggaug      660

aagaggacga agacgaggag gaagaugacg augacgagug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5387
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt3)

<400>  5387
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugcucag cugggugcac uggacccuug cccuguuguu auaccugcau cacgcuaagu      120

ggucccaggc agcccccaca acugagggcg aacaaaaauc ucaugagguc aucaaguuua      180

uggacguuua ucagagauca uacugcaggc cuauugaaac gcuaguggau auauuccagg      240

aguauccaga cgaaaucgag uacauuuuua aaccgaguug uguaccccuc augcggugcg      300

cgggguguug caaugaugag gcucuggaau gugugccuac cagcgagucc aacaucacaa      360

ugcagauuau gcgcaucaag ccacaccaau cucagcauau aggagaaaug ucguuccuuc      420

agcacucacg augcgagugu cgucccaaaa aggacagaac uaagccugag aaaaagagcg      480

ucagggguaa aggcaagggg cagaaacgga agcgcaagaa aaguagauuu aaguccuggu      540

cugugcacug cgaaccaugu agcgagaggc ggaaacaucu guucguucaa gauccccaga      600

ccugcaagug uuccugcaaa aauacagacu cacgcugcaa ggcccgacag uuggaacuca      660

acgagagaac cuguaggugc gauaaaccuc ggcguugagg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5388
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt4)

<400>  5388
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcgacgagac cggcuucgag cacagcggcc ugugggugag cgugcuggcc ggccugcugc      120

ugggcgccug ccaggcccac cccauccccg acagcagccc ccugcugcag uucggcggcc      180

aggugagaca gagauaccug uacaccgacg acgcccagca gaccgaggcc caccuggaga      240

ucagagagga cggcaccgug ggcggcgccg ccgaccagag ccccgagagc cugcugcagc      300

ugaaggcccu gaagcccggc gugauccaga uccugggcgu gaagaccagc agauuccugu      360

gccagagacc cgacggcgcc cuguacggca gccugcacuu cgaccccgag gccugcagcu      420

ucagagagag acugcuggag gacggcuaca acguguacca gagcgaggcc cacggccugc      480

cccugcaccu gcccggcaac aagagccccc acagagaccc cgcccccaga ggccccgcca      540

gauuccugcc ccugcccggc cugccccccg cccugcccga gccccccggc auccuggccc      600

cccagccccc cgacgugggc agcagcgacc cccugagcau ggugggcggc agccagggca      660

gaagccccag cuacgagagc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5389
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt4)

<400>  5389
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

ggggcaccaa gcugcugccc gugcugcugc ugcagcacgu gcugcugcac cugcugcugc      120

ugcacguggc cauccccuac gccgagggcc agaagaagag aagaaacacc cugcacgagu      180

ucaagaagag cgccaagacc acccugacca aggaggaccc ccugcugaag aucaagacca      240

agaaggugaa cagcgccgac gagugcgcca acagaugcau cagaaacaga ggcuucaccu      300

ucaccugcaa ggccuucgug uucgacaaga gcagaaagag augcuacugg uaccccuuca      360

acagcaugag cagcggcgug aagaagggcu ucggccacga guucgaccug uacgagaaca      420

aggacuacau cagaaacugc aucaucggca agggcggcag cuacaagggc accgugagca      480

ucaccaagag cggcaucaag ugccagcccu ggaacagcau gaucccccac gagcacagcu      540

uccugcccag cagcuacaga ggcaaggacc ugcaggagaa cuacugcaga aaccccagag      600

gcgaggaggg cggccccugg ugcuucacca gcaaccccga ggugagauac gaggugugcg      660

acauccccca gugcagcgag guggagugca ugaccugcaa cggcgagagc uacagaggcc      720

ccauggacca caccgagagc ggcaagaccu gccagagaug ggaccagcag accccccaca      780

gacacaaguu ccugcccgag agauaccccg acaagggcuu cgacgacaac uacugcagaa      840

accccgacgg caagcccaga cccuggugcu acacccugga ccccgacacc cccugggagu      900

acugcgccau caagaccugc gcccacagcg ccgugaacga gaccgacgug cccauggaga      960

ccaccgagug cauccagggc cagggcgagg gcuacagagg caccagcaac accaucugga     1020

acggcauccc cugccagaga ugggacagcc aguaccccca caagcacgac aucacccccg     1080

agaacuucaa gugcaaggac cugagagaga acuacugcag aaaccccgac ggcgccgaga     1140

gccccuggug cuucaccacc gaccccaaca ucagaguggg cuacugcagc cagaucccca     1200

agugcgacgu gagcagcggc caggacugcu acagaggcaa cggcaagaac uacaugggca     1260

accugagcaa gaccagaagc ggccugaccu gcagcaugug ggacaagaac auggaggacc     1320

ugcacagaca caucuucugg gagcccgacg ccagcaagcu gaacaagaac uacugcagaa     1380

accccgacga cgacgcccac ggccccuggu gcuacaccgg caacccccug auccccuggg     1440

acuacugccc caucagcaga ugcgagggcg acaccacccc caccaucgug aaccuggacc     1500

accccgugau cagcugcgcc aagaccaagc agcugagagu ggugaacggc auccccaccc     1560

agaccaccgu gggcuggaug gugagccuga aguacagaaa caagcacauc ugcggcggca     1620

gccugaucaa ggagagcugg gugcugaccg ccagacagug cuuccccgcc agaaacaagg     1680

accugaagga cuacgaggcc uggcugggca uccacgacgu gcacgagaga ggcgaggaga     1740

agagaaagca gauccugaac aucagccagc ugguguacgg ccccgagggc agcgaccugg     1800

ugcugcugaa gcuggccaga cccgccaucc uggacaacuu cgugagcacc aucgaccugc     1860

ccagcuacgg cugcaccauc cccgagaaga ccaccugcag caucuacggc uggggcuaca     1920

ccggccugau caacgccgac ggccugcuga gaguggccca ccuguacauc augggcaacg     1980

agaagugcag ccagcaccac cagggcaagg ugacccugaa cgagagcgag cugugcgccg     2040

gcgccgagaa gaucggcagc ggccccugcg agggcgacua cggcggcccc cugaucugcg     2100

agcagcacaa gaugagaaug gugcugggcg ugaucgugcc cggcagaggc ugcgccaucc     2160

ccaacagacc cggcaucuuc gugagagugg ccuacuacgc caaguggauc cacaagguga     2220

uccugaccua caagcuguga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5390
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt4)

<400>  5390
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

agggcgaccc caagaagccc agaggcaaga ugagcagcua cgccuucuuc gugcagaccu      120

gcagagagga gcacaagaag aagcaccccg acgccagcgu gaacuucagc gaguucagca      180

agaagugcag cgagagaugg aagaccauga gcgccaagga gaagggcaag uucgaggaca      240

uggccaaggc cgacaaggcc agauacgaga gagagaugaa gaccuacauc ccccccaagg      300

gcgagaccaa gaagaaguuc aaggacccca acgcccccaa gagacccccc agcgccuucu      360

uccuguucug cagcgaguac agacccaaga ucaagggcga gcaccccggc cugagcaucg      420

gcgacguggc caagaagcug ggcgagaugu ggaacaacac cgccgccgac gacaagcagc      480

ccuacgagaa gaaggccgcc aagcugaagg agaaguacga gaaggacauc gccgccuaca      540

gagccaaggg caagcccgac gccgccaaga agggcguggu gaaggccgag aagagcaaga      600

agaagaagga ggaggaggag gacgaggagg acgaggagga cgaggaggag gaggaggacg      660

aggaggacga ggacgaggag gaggacgacg acgacgagug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5391
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt4)

<400>  5391
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugcugag cugggugcac uggacccugg cccugcugcu guaccugcac cacgccaagu      120

ggagccaggc cgcccccacc accgagggcg agcagaagag ccacgaggug aucaaguuca      180

uggacgugua ccagagaagc uacugcagac ccaucgagac ccugguggac aucuuccagg      240

aguaccccga cgagaucgag uacaucuuca agcccagcug cgugccccug augagaugcg      300

ccggcugcug caacgacgag gcccuggagu gcgugcccac cagcgagagc aacaucacca      360

ugcagaucau gagaaucaag ccccaccaga gccagcacau cggcgagaug agcuuccugc      420

agcacagcag augcgagugc agacccaaga aggacagaac caagcccgag aagaagagcg      480

ugagaggcaa gggcaagggc cagaagagaa agagaaagaa gagcagauuc aagagcugga      540

gcgugcacug cgagcccugc agcgagagaa gaaagcaccu guucgugcag gacccccaga      600

ccugcaagug cagcugcaag aacaccgaca gcagaugcaa ggccagacag cuggagcuga      660

acgagagaac cugcagaugc gacaagccca gaagaugagg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5392
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt5)

<400>  5392
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcgaugagac cggcuucgaa cacuccgggc uguggguguc uguccucgcc ggacugcuuc      120

ugggcgcuug ccaggcccau cccaucccug acagcucccc gcuccugcaa uuugggggac      180

agguuagaca gcgguaccuu uauacagaug acgcgcagca aacggaggcu caccuggaaa      240

uucgcgagga uggcaccgug ggcggagccg ccgaccaguc ucccgaaagc cuccugcagc      300

ugaaggcucu caaaccuggc gugauccaga uucugggcgu caagacaucc agauuccuuu      360

gucaacggcc cgauggggcc cuguacggau cucuccauuu ugacccugag gcuugcagcu      420

uccgcgagag acugcuugaa gauggcuaua acguguacca guccgaggcc cacgggcugc      480

cccuccaucu gccuggaaau aaaagcccgc accgggaccc cgcgccucgc ggccccgcca      540

gauuucugcc ucuccccggg cugccgccug cccuucccga accucccgga auccuggcuc      600

cccagccucc ggauguuggg ucuuccgacc cccucagcau ggugggcggg ucucagggac      660

gguccccuag cuaugagucu ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5393
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt5)

<400>  5393
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

ggggcaccaa gcugcucccc gugcugcuuc ugcagcacgu ccuccugcau cuucugcucc      120

ugcacguugc caucccuuac gcugaggggc agaaaaagag acggaacaca cugcaugagu      180

ucaaaaagag cgccaaaacg acccucacaa aggaagaccc gcugcuuaag auuaaaacca      240

agaaagucaa uuccgcggau gaaugcgcua accgcuguau cagaaaucgg ggauuuacau      300

uuaccugcaa ggccuucgug uucgacaaau cucgcaagag auguuauugg uaccccuuua      360

acagcauguc cucuggcgug aagaaagggu ucggacacga guuugaucug uaugaaaaua      420

aggacuacau ucggaacugc aucauuggca aagggggaag cuauaagggc acagugucca      480

ucaccaaauc uggcaucaag ugucaaccuu ggaauagcau gauuccccau gagcacuccu      540

uccucccuag cucuuaccgc gggaaagauc ugcaggagaa cuauugcaga aauccccggg      600

gagaagaggg cgggccuugg uguuuuacgu ccaacccgga aguucgcuac gaggugugcg      660

acauccccca guguagcgag gucgaaugca ugaccuguaa uggagagucu uacagaggcc      720

cuauggauca cacagaaucc gggaagaccu gccaacggug ggaccagcag acaccccauc      780

gccacaaguu ccuuccugag agauaucccg auaaaggauu ugacgauaac uacugccgga      840

auccggacgg caagccucgc cccugguguu auacccugga uccugacacg cccugggaau      900

acugcgccau uaaaacaugu gcucauagcg ccgugaacga gaccgacguu cccauggaga      960

caaccgaaug cauccagggc caaggggagg gauauagagg caccucuaau acaauuugga     1020

acgggauccc uugucagcgg ugggauuccc aguacccgca caagcacgac auuacgcccg     1080

aaaacuucaa augcaaggau cucagagaga auuauugucg caacccugac ggagcugaaa     1140

gccccuggug cuuuaccaca gauccuaaua uccggguggg cuacuguucc cagaucccca     1200

agugcgacgu cucuagcggg caagauuguu acagaggaaa cggcaaaaau uauaugggca     1260

accuguccaa gacccgcagc gggcugacau gcucuaugug ggacaaaaau auggaggauc     1320

uccaucggca cauuuucugg gagccggacg ccuccaagcu gaacaaaaau uacugcagaa     1380

acccugauga cgacgcgcau ggacccuggu guuauaccgg caauccucuu auccccuggg     1440

auuacugccc uauuagccgc ugugaagggg acacgacacc caccaucgug aaccuggauc     1500

acccggugau uucuugcgcc aagaccaagc agcuccgggu cguuaaugga aucccuacac     1560

agaccacagu gggcuggaug gugagccuga aauauagaaa caagcauauc ugugggggcu     1620

cccuuauuaa agagucuugg guccugacgg cucgccaaug cuuccccgcc cggaauaagg     1680

accucaaaga uuacgaggcu uggcugggaa uccacgacgu gcacgaaaga ggcgaagaga     1740

agcgcaagca gauucugaac aucagccagc ucguuuaugg gcccgaggga uccgaucugg     1800

ugcuucugaa acucgcccgg ccugcgauuc uggacaacuu ugucagcacc aucgaucuuc     1860

cgucuuacgg cuguacaauc cccgaaaaga ccacaugcuc cauuuacggg uggggauaua     1920

ccggccugau caaugccgac gggcuccuga gaguggcuca ucuguacauu augggcaacg     1980

agaaauguag ccagcaccau caaggaaagg uuacgcucaa ugaaucugag cugugcgccg     2040

gcgcugagaa aaucgggucc ggaccuugug aaggcgauua ugggggaccc cuuauuugcg     2100

agcagcacaa gaugcggaug gugcugggcg ucaucgugcc ugggcgcggc ugcgccauuc     2160

ccaacagacc uggaaucuuc guccgggugg ccuacuaugc uaaauggauc cacaagguua     2220

uucucaccua caagcuguga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5394
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt5)

<400>  5394
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

agggggaccc caaaaagccu agaggaaaaa ugagcuccua cgccuucuuu gugcagaccu      120

gccgggagga acacaagaaa aagcauccgg augcuucugu caacuucagc gaguuuucca      180

agaaauguuc ugaacgcugg aagacaauga gcgccaaaga gaagggcaaa uucgaagaca      240

uggcgaaggc ugauaaggcc agauaugagc gggagaugaa aacguacauu cccccuaagg      300

gggaaaccaa aaagaaauuu aaggacccca augccccuaa aagacccccu uccgcuuucu      360

uucuguucug cucugaguau cgcccgaaga ucaagggaga acaccccggc cucagcaucg      420

gggauguugc caaaaagcug ggagagaugu ggaacaauac agcugccgac gauaaacaac      480

cuuacgagaa gaaagcggcc aaacuuaagg aaaaguauga gaaggacauu gcugccuacc      540

gggcuaaagg caagcccgau gccgcgaaaa agggcguggu gaaggccgaa aaauccaaga      600

aaaagaaaga ggaagaggag gacgaagagg augaagagga cgaagaggag gaagaggaug      660

aagaggacga agacgaggag gaagaugacg augacgagug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5395
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt5)

<400>  5395
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugcucag cugggugcac uggacccugg cccuucugcu cuaccugcau cacgcuaagu      120

ggucccaggc cgcgcccaca acggagggcg aacaaaaauc ucaugagguc aucaaguuua      180

uggacguuua ucagagaagc uacugccggc cuauugaaac ccuuguggau aucuuccagg      240

aguauccgga cgaaauugag uacaucuuua aacccuccug ugugccucug augcgcugcg      300

cuggguguug caaugaugag gcccucgaau guguccccac aucugagagc aacauuacca      360

ugcagaucau gagaaucaag ccucaccaau cccagcauau uggagaaaug ucuuuccugc      420

agcacagccg gugcgagugu cgccccaaaa aggacagaac aaagccugag aaaaaguccg      480

ugcggggcaa agggaaggga cagaaacgca agagaaagaa aagccgguuu aagucuuggu      540

ccguucacug cgaaccgugu agcgagcgca gaaaacaucu guucgugcaa gauccccaga      600

ccugcaagug uucuugcaaa aauacagacu cccggugcaa ggcccgccag cucgaacuga      660

acgagagaac cugucggugc gauaaaccuc gcagaugagg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5396
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt6)

<400>  5396
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggauu       60

cagaugaaac aggauuugaa cacucaggau uaugggucuc aguuuuagca ggacuauuac      120

uaggagcaug ucaagcacau ccaauaccag acucaagccc auuauuacaa uuuggaggac      180

aaguaagaca aagauauuua uauacagaug acgcacaaca aacagaagca cauuuagaaa      240

uaagagaaga cggcacagua ggaggagcag cagaucaauc accagaauca cuauuacaau      300

uaaaagcauu aaaaccagga guaauacaaa uauuaggagu aaaaacauca agauucuuau      360

gccaaagacc ugacggagca uuauaugguu cacuacacuu ugacccagaa gcauguucau      420

ucagagaaag acuacuagaa gacggauaua auguuuacca aucugaagca cauggauuac      480

cacuacacuu accaggaaau aaaucaccac accgagaccc agcaccacga ggaccagcaa      540

gauuccuacc acuaccagga uuaccaccag cauuaccaga accaccagga auacuagcuc      600

cacaaccacc agacguagga uccucagauc cauuaucaau gguaggagga ucucaaggua      660

gaagucccuc auacgaauca uaaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5397
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt6)

<400>  5397
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

ggggaacaaa acuauuacca guauuauuau uacaacaugu cuuauuacau uuacuucuac      120

uacauguugc aauacccuau gccgaaggac aaaagaaaag aagaaacacu cuucacgagu      180

ucaagaaaag cgcaaaaaca acauuaacaa aagaagaccc acuacuaaaa auaaaaacaa      240

agaaaguaaa cucagcagau gaaugugcca acagauguau uagaaaccgg gguuuuacuu      300

uuacaugcaa agccuucgua uucgauaaau caaggaaaag augcuacugg uauccauuca      360

auucaauguc auccggaguc aagaaaggau ucggccauga auuugaccua uacgaaaaua      420

aagauuauau cagaaacugu auaauaggaa aaggugguuc auacaaagga acaguaucaa      480

uaacaaaaag cgguauuaaa ugucaacccu ggaacucuau gauuccucau gaacauucau      540

uuuuaccauc aucauacaga gguaaagacu uacaagaaaa uuacugcaga aauccaaggg      600

gagaagaagg cggaccaugg ugcuuuacau caaaucccga aguaagauau gaaguaugcg      660

acauaccaca auguagugaa guugaaugua ugacauguaa uggagaaagc uacagagguc      720

caauggauca uacagaauca ggaaaaacau gccaaagaug ggaucaacaa acaccgcaua      780

gacauaaauu uuuaccagaa agauauccag auaaaggauu cgaugacaau uacuguagga      840

aucccgacgg aaaaccacga ccauggugcu auacacuaga cccugauacu ccaugggaau      900

auugcgcuau aaaaacuugu gcacauucag caguaaacga aaccgacgua ccaauggaaa      960

ccacugaaug uauacaaggg caaggagaag gauacagagg aacaucaaau acaauaugga     1020

acggaauacc cugucaaaga ugggauagcc aauauccaca uaaacacgac auaaccccag     1080

aaaacuuuaa auguaaagau cuaagagaaa auuacugcag aaaucccgau ggcgcagaau     1140

caccauggug cuucacaaca gaucccaaca uaagagucgg auauugcucc cagauuccua     1200

aaugugaugu aagcuccggg caagacugcu accgaggcaa cgguaaaaau uacaugggaa     1260

acuuaaguaa aacaagauca ggauuaacau gcaguaugug ggauaaaaau auggaggacu     1320

uacauagaca uauauucugg gaaccagaug caucaaaacu uaacaaaaau uauugcagaa     1380

acccagacga cgaugcacac ggaccauggu guuauacagg aaauccacuu auaccauggg     1440

acuauugucc aauaucacga ugcgaaggag auacaacacc aacaauagua aacuuagauc     1500

auccaguaau aaguugcgca aaaacuaaac aauuacgagu uguuaacgga auaccaacac     1560

aaacuacagu cggauggaug guuucauuaa aauauagaaa caaacacaua ugcggaggau     1620

cccuuauaaa agaauccugg guauuaacag caagacaaug uuuuccagcc agaaauaaag     1680

aucucaaaga cuacgaagca ugguuaggca uacacgaugu acaugaacga ggagaagaaa     1740

aacgaaaaca aauauuaaau auaagccagc uaguuuaugg accagaagga ucggacuuag     1800

uacuauuaaa acuugcaaga ccagcaaucc uagacaauuu ugucucaaca aucgacuuac     1860

ccucauaugg augcacuauu ccggagaaaa caacaugcuc cauauacgga uggggauaua     1920

caggauugau aaaugcagau ggauuacuaa gaguagcaca ucuauacaua augggaaaug     1980

aaaaauguuc acaacaccau caaggaaaag uaacacuaaa cgaaagcgaa uuaugugcag     2040

gcgcagagaa aauaggcagu ggaccaugug aaggagauua cgguggacca cuaauaugcg     2100

aacaacauaa aaugagaaug guccuaggag uaauaguccc cggaagagga ugugcaauac     2160

caaaucgacc gggcauauuu guaagaguag cauacuacgc aaaauggaua cacaaaguaa     2220

uacuaacaua caaacuauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5398
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt6)

<400>  5398
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

aaggagaccc aaaaaaacca agaggaaaaa ugucaagcua cgcauucuuc guacaaacau      120

gcagagaaga acacaaaaaa aaacacccag acgcaagcgu aaacuucagc gaauucagca      180

aaaaauguuc agaaagaugg aaaacaauga gcgcaaaaga aaaaggaaaa uucgaagaca      240

uggcaaaagc agacaaagca agauacgaaa gagaaaugaa aacauacaua ccaccaaaag      300

gagaaacaaa aaaaaaauuc aaagacccaa acgcgccaaa aagaccacca ucagcauucu      360

ucuuauucug cagugaauac agaccaaaaa uaaaaggaga acacccagga cuaaguauag      420

gagacguagc aaaaaaacua ggagaaaugu ggaacaacac agcagcagac gacaaacaac      480

cauacgaaaa aaaagcagca aaacuaaaag aaaaauacga aaaagacaua gcggcauaca      540

gagcaaaagg aaaaccagac gcagcaaaaa aaggaguagu aaaagcagaa aaaaguaaaa      600

aaaaaaaaga agaagaagaa gacgaagaag acgaagaaga cgaagaagaa gaagaagacg      660

aagaagacga agacgaagaa gaagacgacg acgacgaaua aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5399
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt6)

<400>  5399
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuauuaag cuggguacac uggacacuag cacuacuacu auacuuacac cacgccaaau      120

ggagccaagc agcaccaaca acagaaggag aacaaaaauc acacgaagua auaaaauuca      180

uggacguaua ccaaagauca uacuguagac caauagaaac acuaguagac auauuccaag      240

aauacccaga cgaaauagaa uacauauuca aaccaucaug cguaccacua augagaugcg      300

caggaugcug caacgacgaa gcacuagaau gcguaccaac aucagaauca aacauaacaa      360

ugcaaauaau gagaauaaaa ccacaccaaa gucaacacau aggagaaaug aguuuccuac      420

aacacucaag augcgaaugc agaccaaaaa aagacagaac aaaaccagaa aaaaaaucag      480

uaagaggaaa aggaaaaggc caaaaaagaa aaagaaaaaa aucaagauuc aaaagcuggu      540

caguacacug ugaaccaugu ucagaaagaa gaaaacaccu auucguacaa gacccacaaa      600

caugcaaaug caguugcaaa aacacagacu caagaugcaa agcaagacaa cuagaauuaa      660

augaacgaac augcagaugc gacaaaccaa gaagauaagg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5400
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt7)

<400>  5400
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaca       60

gcgaugagac cggcuucgaa cacuccgggc ugugggugag uguccucgcc ggucuguugc      120

ugggcgcaug ccaggcccau cccaucccag acagcucccc gcuccugcaa uuugggggcc      180

aggugaggca gcgguacuug uauacugaug acgcgcagca aaccgaggcc caccuggaaa      240

uucgcgagga ugguacggua gggggcgcag ccgaccagag ucccgaaagc cuccugcagc      300

ugaaggcacu caaaccaggc gugauccaga uucugggggu caagacuucc agguucuugu      360

gucaacggcc cgauggugcc cuguacggca gccuccauuu ugacccagag gcgugcuccu      420

uccgcgagag gcugcuggaa gauggguaua acguguacca gagugaggcc cacggcuugc      480

cccuccaucu gccagguaau aaaagcccgc accgggaccc cgcaccacgc gggcccgcca      540

gguuucugcc acuccccggc cugccgcccg ccuugccaga acccccaggc auccuggcac      600

cccagccacc ggaugugggg uccagcgacc cccucaguau ggucgguggc ucccaggggc      660

ggagcccauc cuaugagagu ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5401
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt7)

<400>  5401
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

ggggcaccaa gcugcucccc gugcuguugc ugcagcacgu ccuccugcau uugcugcucc      120

ugcacguggc caucccauac gcagaggggc agaaaaagag gcggaacacu cugcaugagu      180

ucaaaaagag cgccaaaacc acgcucacua aggaggaccc gcuguugaag auuaaaacca      240

agaaaguaaa uuccgcggau gaaugcgcca accgcuguau caggaaucgg gguuuuaccu      300

ucacuugcaa ggcauuugug uucgacaaaa gucgcaagag guguuauugg uaccccuuua      360

acagcauguc caguggcguc aaaaaggggu ucggccacga guuugaucug uaugaaaaua      420

aggacuacau ucggaacugc aucauuggua aagggggcag cuauaagggc accgugucca      480

ucacgaaaag cgggaucaag ugucaaccau ggaacuccau gauuccccau gagcacaguu      540

uccucccaag cuccuaccgc gguaaagauc ugcaggagaa uuauugcagg aauccccggg      600

gcgaagaagg gggcccaugg uguuuuacua gcaacccgga agugcgcuac gaggucugcg      660

acauccccca guguagugag guggaaugca ugaccugcaa uggugagucc uacagggggc      720

caauggauca cacugaaagc ggcaagaccu gucaacggug ggaccagcag acuccccauc      780

gccacaaguu ccugccagag agguaucccg auaaaggcuu ugacgauaac uacugccgga      840

auccggacgg gaagccccgc ccaugguguu auacguugga ucccgacacu ccaugggaau      900

acugcgccau uaaaaccugu gcacauuccg ccguaaacga gacugacgug cccauggaga      960

ccaccgaaug cauccagggu caaggcgagg gguauagggg caccaguaau acgauuugga     1020

acgguauccc augucagcgg ugggauagcc aguacccgca caagcacgac auuacccccg     1080

aaaacuucaa augcaaggau cuccgcgaga auuauuguag gaacccagac ggcgcggaau     1140

cccccuggug cuucacuacc gauccaaaua uccgggucgg guacugcagc cagaucccca     1200

agugugacgu gaguuccggc caagauugcu acagggggaa cgguaaaaau uauaugggca     1260

accugagcaa gacccgcagu gggcugacuu guuccaugug ggacaaaaau auggaggauc     1320

uccaucggca caucuuuugg gagccggacg ccagcaagcu gaacaaaaau uacugcagga     1380

acccagauga cgacgcacau ggccccuggu guuauacggg uaaucccuug auuccauggg     1440

auuacugccc cauuagccgc ugugaaggcg acaccacucc aaccaucgug aaccuggauc     1500

acccggucau uuccugcgcc aagaccaagc agcuccgggu gguaaauggg auccccacuc     1560

agacgaccgu gggcuggaug gucagucuga aauauaggaa caagcauauc ugugggggca     1620

gccugauuaa agaguccugg guguugacug cccgccaaug cuucccagca cggaauaagg     1680

accucaaaga uuacgaagcc uggcugggua uccacgacgu gcacgagagg ggcgaagaga     1740

agcggaaaca gauucugaac aucagccagc ucgucuaugg gcccgagggu agugaucugg     1800

uguugcugaa gcucgcgcgc ccagccauuc uggacaacuu uguauccacc aucgaucugc     1860

ccagcuacgg cuguacuauc ccggaaaaga ccacgugcuc cauuuacggg uggggcuaua     1920

ccggguugau caaugcagac ggccuccuga ggguggccca ucuguacauu auggguaacg     1980

agaaaugcag ucagcaccau caagggaagg ucacucucaa ugaaagcgag cugugugcag     2040

gcgccgagaa aaucggcucc gggccaugcg aaggugauua uggcgggccc uugauuugug     2100

agcagcacaa gaugcggaug gugcugggcg ucaucgugcc aggucgcggg ugcgccauuc     2160

ccaacaggcc gggcaucuuc gugcggguag cguacuaugc aaaauggauc cacaagguga     2220

uucucaccua caagcuguga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5402
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt7)

<400>  5402
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

agggggaccc caaaaagcca agggguaaaa ugagcuccua cgccuucuuu gugcagaccu      120

gccgggagga acacaagaaa aagcauccgg augcaagugu caacuucagc gaguuuucca      180

agaaauguag ugaacgcugg aagacuauga gcgccaaaga gaagggcaaa uucgaagaca      240

uggcgaaggc cgauaaagca agguaugagc gggagaugaa gaccuacauu cccccaaagg      300

gggaaacgaa aaagaaauuu aaggacccca augccccaaa aaggccccca uccgcauucu      360

uucuguucug cagcgaguau cgcccgaaga ucaagggcga acaccccggu cucuccaucg      420

gggauguggc caaaaagcug ggcgagaugu ggaacaauac ugcggccgac gauaaacaac      480

cauacgagaa gaaagcagcc aaguugaagg aaaaauauga gaaggacauu gccgcauacc      540

gggccaaagg caagcccgau gcggccaaaa aggggguagu gaaggcagag aaaaguaaga      600

aaaagaaaga agaagaggag gacgaagagg augaagagga cgaagaggag gaagaggaug      660

aagaggacga agacgaggag gaagaugacg augacgagug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5403
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt7)

<400>  5403
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccugcucag cugggugcac uggacccugg ccuugcugcu cuaccugcau cacgcaaagu      120

ggucccaggc cgcgcccacu accgagggcg aacagaaaag ucaugagguc aucaaguuua      180

uggacgugua ucaaaggagc uacugccggc caauugaaac guugguagau aucuuccagg      240

aguauccgga cgaaauugag uacaucuuua aacccuccug ugugccacug augcgcugcg      300

ccggguguug caaugaugag gcacucgaau guguccccac cagugagagc aacauuacua      360

ugcagaucau gaggaucaag ccacaccaau cccagcauau uggugaaaug agcuuccugc      420

agcacucccg gugcgagugu cgccccaaaa aggacaggac caagccagag aaaaagagug      480

ugcggggcaa agggaagggc cagaaacgca agaggaaaaa gagccgguuu aaguccugga      540

gcgugcacug cgaaccgugu agugagcgca ggaaacaucu guucguccaa gauccccaga      600

cuugcaagug cuccuguaaa aauaccgaca gccggugcaa ggcccgccag cucgaacuga      660

acgagaggac gugucggugc gauaaaccaa ggcgcugagg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5404
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt8)

<400>  5404
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

cugacgaaac cggcuucgaa cacuccggac ucugggucuc cguccucgcc ggccuccucc      120

uaggcgccug ccaagcccac cccauccccg acucaucccc acuccuacaa uucggcggcc      180

aaguccguca acgcuaccuc uauaccgaug acgcccaaca aaccgaagcc caccucgaaa      240

uccgcgaaga cggaaccguc ggcggcgccg cugaccaauc acccgaaucc cuccuccaac      300

ucaaagcacu caaacccggc guaauccaaa uccucggcgu aaaaaccuca cgauuucuau      360

gucaaagacc cgacggagcc cuauacggcu cucuacacuu cgacccagaa gcaugcuccu      420

uccgcgaacg acuccucgaa gacggauaca acgucuacca aucagaagcc cacggccuac      480

cccuccaccu ccccggcaac aaaucucccc accgcgaccc cgcaccccgc ggccccgccc      540

gcuuccuccc ccuccccggc cuacccccag cccuacccga accacccggc auacucgcac      600

cccaaccacc cgacgucggc uccuccgacc cccuauccau ggucggcggc ucccaaggcc      660

gcucccccuc auacgaaucu uaaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5405
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt8)

<400>  5405
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

ggggcacgaa acugcuccca guauugcucu ugcaacacgu ccuacuccac cuucuacugc      120

uacacgucgc uauacccuau gccgaaggac aaaagaaacg ucgcaacacc cuacacgaau      180

uuaagaaaag cgccaagacc acacucacua aagaagaucc ccuacucaaa auaaagacca      240

aaaaggugaa cucggcugac gaaugcgcca accgaugcau ccgaaacaga ggcuucacuu      300

uuaccugcaa agccuucguu uucgacaaga gccgaaaacg augcuacugg uacccauuca      360

acagcauguc cuccggggua aagaaaggcu ucggacauga guucgaucua uacgaaaaua      420

aagacuacau aagaaacugc auaaucggca aaggaggguc cuacaaaggc acagucagca      480

ucacaaaguc agggaucaaa ugccaacccu ggaacuccau gauaccacac gagcacaguu      540

uccucccuag uagcuaccga ggaaaagacc uccaggagaa cuacugccgc aacccccgcg      600

gggaagaagg cggaccuugg ugcuucacaa gcaaccccga gguccgcuac gaggucugcg      660

acauccccca augcagcgaa gucgagugca ugaccuguaa cggagaauca uaccgaggcc      720

caauggauca caccgaaucc ggaaaaacau gccaacgaug ggaccaacaa acaccgcacc      780

gacacaaguu ccuccccgaa cgguaccccg acaaaggauu cgacgacaac uacugccgca      840

accccgacgg aaaaccacga ccauggugcu acacgcucga cccggacacc cccugggaau      900

acugcgccau caaaaccugc gcacacucag cggugaacga aaccgaugua ccaauggaaa      960

caaccgaaug cauccaagga caaggagagg gcuacagggg cacgucaaau accaucugga     1020

acggcauacc augccagcgc ugggacaguc aguaccccca caaacacgac auaacccccg     1080

aaaacuucaa augcaaagac cucagagaaa acuacugccg caaccccgac ggcgccgaau     1140

cccccuggug uuucacaacc gacccaaaca uccgcguggg cuacugcuca caaaucccca     1200

agugcgacgu aucaagcggc caagacugcu aucgcgggaa cggcaaaaac uacaugggaa     1260

accucucaaa gaccagaagc ggccuaacau gcucaaugug ggacaaaaac auggaggacc     1320

uccaccggca caucuuuugg gaacccgacg cuuccaaacu caacaaaaac uacugccgaa     1380

accccgacga cgaugcacac ggcccauggu gcuacacagg caacccccug auacccuggg     1440

acuacugccc caucuccaga ugcgagggcg acacaacacc gaccaucgua aaucucgacc     1500

accccguaau cuccugcgcc aaaacaaaac aacuaagggu cgugaacgga auccccaccc     1560

aaacaacagu gggcuggaug gucagccuca aauacagaaa caagcacauc ugcggcggcu     1620

cccucaucaa ggaaagcugg guacuaacag ccaggcaaug cuuccccgcc agaaauaaag     1680

aucuaaaaga cuacgaagcc uggcuaggca uccaugacgu ccacgaacgc ggcgaggaga     1740

aacgaaaaca aauucucaac aucucucaac ucgucuaugg accagaaggg agcgaccucg     1800

uucuucugaa acucgcccgg cccgcaaucu uagacaacuu cgucagcaca aucgaccucc     1860

ccucauacgg augcaccauc ccagaaaaga caaccugcag cauauacgga uggggcuaca     1920

ccggccugau caacgcagac ggccuucuca gagucgccca ucucuacauc augggaaacg     1980

aaaaaugcag ccaacaccac caaggcaaag uaacgcucaa cgaauccgaa cucugcgccg     2040

gagcagggac uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa     2100

gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca     2160

cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu     2220

aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc     2340

cccccccaaa ggcucuuuuc agagccacca gaauu                                2375


<210>  5406
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt8)

<400>  5406
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

aaggggaccc gaaaaagcca agaggaaaga ugucgagcua ugccuuuuuc gugcaaacgu      120

gcagggaaga acacaagaaa aagcacccgg acgcgagcgu gaacuuuagc gaguucucga      180

aaaagugcuc agaaaggugg aagaccauga gcgcgaaaga aaaagggaaa uuugaagaua      240

uggcaaaagc ggacaaggca agguacgagc gagaaaugaa gacauauauc ccgccaaagg      300

gcgagacaaa gaagaaauuc aaagacccga acgcgcccaa gcgcccgcca ucggccuuuu      360

uccuauucug cagcgaguac aggcccaaga uaaagggcga gcacccagga uugagcauag      420

gcgaugucgc gaaaaagcua ggggaaaugu ggaacaacac ggccgcggac gauaaacagc      480

cguaugaaaa gaaagcggcc aagcucaagg aaaaguacga gaaagauauc gcggccuaua      540

gagcgaaagg aaaaccggac gcggccaaga aagggguagu gaaagcggaa aagagcaaga      600

aaaagaaaga ggaagaggaa gaugaagagg acgaggaaga cgaagaggaa gaggaagaug      660

aagaggacga ggacgaggaa gaggacgaug acgaugaaua gggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5407
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt8)

<400>  5407
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuccucuc cuggguccac uggacccucg cccuccuccu cuaccuucac cacgcaaaau      120

ggucccaagc cgcccccacc accgaaggag aacaaaaauc ccacgaaguc auaaaauuca      180

uggacguaua ccaacgauca uacugccgac ccaucgaaac ccuagucgac aucuuccaag      240

aauacccaga cgaaaucgaa uacauauuca aacccuccug cguaccccuc augcgcugcg      300

ccggcugcug caacgacgaa gcccuagaau gcgucccaac aucagaauca aacaucacca      360

ugcaaaucau gcgcaucaaa ccacaccaau cccaacacau aggcgaaaug uccuuccucc      420

aacacucacg cugcgaaugc cgccccaaaa aagaccgaac caaacccgaa aaaaaaucag      480

uccgaggcaa aggaaaaggc caaaaacgca agcgcaaaaa aucccgcuuc aaauccuggu      540

ccguccacug cgaacccugc uccgaacgcc gaaaacaccu cuucguccaa gacccacaaa      600

ccugcaaaug cuccugcaaa aacaccgacu ccagaugcaa agcacgccaa cucgaacuca      660

acgaaagaac cugccgcugc gacaaacccc gccgcuaagg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5408
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt9)

<400>  5408
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

ccgacgaaac cggauucgaa cacucaggcc ucugggucuc aguccucgcc ggccuccucc      120

ucggagccug ccaagcccac ccaauccccg acuccucacc acuccuccaa uucggcggcc      180

aaguccgaca acgauaccuc uacaccgacg acgcccaaca aaccgaagcc caccucgaaa      240

uccgcgaaga cggcacagua ggaggcgccg ccgaccaauc acccgaaucc cuacuccaac      300

uaaaagcacu caaacccggc gucauccaaa uacucggcgu caaaaccuca agauuccucu      360

gccaacgccc cgacggcgcc cucuacggcu cccuccacuu cgaccccgaa gccugcuccu      420

uccgcgaacg ccuccucgaa gacggcuaca acgucuacca auccgaagcc cacggccucc      480

cccuccaccu cccaggcaac aaauccccac accgcgaccc cgcaccccgc ggcccagccc      540

gcuuccuccc ccuccccgga cuacccccug cccuacccga accaccaggc auccucgcac      600

cccaaccacc cgacgucggc uccuccgacc cccucucaau gguaggcggc ucacaaggcc      660

gaucccccuc cuacgaaucc uaaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5409
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt9)

<400>  5409
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

ggggcacaaa acuccuuccg guacugcugc uacaacacgu gcuucuccac cuccuucuac      120

uccacgucgc aauccccuau gcagaagggc agaaaaagcg acgcaacaca cuccacgagu      180

ucaagaaauc ggccaaaaca acccuaacca aagaggaccc ccuccucaaa aucaaaacca      240

agaaaguaaa cuccgccgac gagugcgcca acagaugcau ccgcaaccgg ggcuucaccu      300

ucacaugcaa agccuucgug uucgauaaaa gccgcaaacg augcuacugg uacccauuca      360

acuccaugag cucgggaguu aagaaaggcu uuggccacga auuugaccua uacgagaaua      420

aagacuacau aagaaacugc aucaucggua aaggcggcuc auacaaaggg accguaucca      480

ucacaaaaag cggaauaaaa ugccaaccgu ggaacucuau gauaccccac gaacacucau      540

uccuaccauc cucauaccgc ggcaaagacc uacaagagaa cuacugccga aacccccgag      600

gagaagaagg gggaccaugg ugcuucaccu caaacccaga gguacgguac gaagucugcg      660

acaucccaca augcagcgaa guagagugca ugaccuguaa cggagagucc uaccggggac      720

caauggacca uaccgaaucg ggaaaaacuu gccaacgaug ggaucaacaa acaccccauc      780

gucacaaauu ccuaccggaa cgauacccag acaaaggauu cgacgacaac uacugcagaa      840

aucccgacgg uaaacccaga ccuuggugcu acacccuaga ccccgacacc ccaugggaau      900

acugcgccau aaagaccugc gcacacucug ccgucaacga gaccgacguc cccauggaaa      960

caaccgaaug cauacagggg cagggagagg gcuaccgcgg caccagcaac accaucugga     1020

acgguauacc cugccagcga ugggacagcc aauaccccca caagcacgac auaaccccug     1080

agaacuucaa gugcaaagac cuacgcgaaa acuacugccg aaacccagac ggcgccgaau     1140

caccauggug uuucacaaca gacccaaaca uccgcgucgg cuacugcucc caaauaccca     1200

aaugcgacgu caguuccgga caagacugcu accgaggcaa cggaaagaac uacaugggaa     1260

accucuccaa aacccguagc gguuuaacau gcuccaugug ggacaagaac auggaagacc     1320

uacacagaca uauauucugg gaacccgacg caagcaaacu caacaaaaau uacugccgca     1380

accccgacga cgaugcccau ggccccuggu gcuacaccgg caacccccug auccccuggg     1440

acuacugucc aauaagccga ugcgaggggg acaccacccc uaccaucguc aaccuggacc     1500

accccgucau cuccugcgca aaaaccaaac agcuccgagu agugaacggc aucccaaccc     1560

agacaacggu cggauggaug gucucacuaa aauaccgaaa caaacacaua ugcgguggau     1620

cccucaucaa agaaagcugg gucuuaaccg cccgccaaug cuuccccgca cgaaacaaag     1680

accuaaaaga cuacgaagca uggcuaggca uccacgacgu acacgaacga ggcgaagaaa     1740

aacgaaagca aauccucaac aucucacagu uagucuacgg accagaaggu ucagaccucg     1800

ugcuccuaaa guuagcccgc cccgccauac uagacaacuu cgucagcacc aucgaccuac     1860

caucauacgg augcaccaua ccagagaaaa ccacaugcag uaucuacggc uggggcuaca     1920

cgggccucau caacgccgac ggccuccuac gcguagccca ccucuauauc augggcaacg     1980

aaaaaugcuc acaacaccac caagggaaag uaacacugaa cgaauccgag cucugcgccg     2040

gcgccgagaa aaucggaucc ggccccugcg aaggagacua cgggggacca cuaauaugcg     2100

aacagcacaa gaugcgaaug guccucggag ucaucguacc cggccgaggc ugcgcaauac     2160

ccaaucgccc cggcauauuc guucgcguag ccuacuacgc uaaauggauc cacaaaguca     2220

uacucaccua caaacuauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5410
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt9)

<400>  5410
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

aaggggaccc gaagaaacca aggggaaaaa ugucgagcua ugccuucuuc gugcaaacgu      120

gcagggagga acacaagaaa aagcacccag acgcgagcgu gaacuuuagc gaguucucga      180

aaaagugcuc ggaaaggugg aagacaauga gcgcgaaaga gaaagggaaa uuugaagaua      240

uggcgaaagc ggacaaggcc agguacgagc gagagaugaa gaccuauauc ccgcccaagg      300

gcgagacaaa gaagaaauuc aaagacccga acgcgccaaa gcgcccgccc ucggcauuuu      360

ucuuguucug uagcgaguac aggccaaaga ucaagggcga gcacccaggc uugagcauag      420

gcgaugucgc caaaaagcuc ggggaaaugu ggaauaacac agcagcagac gauaaacagc      480

ccuaugaaaa gaaagcggca aagcucaagg aaaaguacga gaaagauauc gcggccuauc      540

gcgcgaaagg gaaaccggac gcggcaaaga aaggggucgu gaaagcggaa aagagcaaga      600

aaaagaaaga ggaagaggaa gaugaagagg acgaggaaga ugaagaggaa gaggaagaug      660

aagaggacga ggacgaagaa gaggacgaug acgaugaaua gggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5411
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt9)

<400>  5411
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuccucuc cuggguccac uggacacucg cccuccuccu auaccuacac cacgccaaau      120

ggagccaagc cgcccccaca accgaaggcg aacaaaaauc ccacgaaguc aucaaauuca      180

uggacgucua ccaacgcucc uacugccgcc ccaucgaaac ccucgucgac aucuuccaag      240

aauaccccga cgaaaucgaa uacaucuuca aacccuccug cgucccccuc augcgcugcg      300

ccggcugcug caacgacgaa gcccucgaau gcguccccac cucagaauca aacauaacaa      360

ugcaaaucau gcgcaucaaa ccccaccaau cccaacacau cggagaaaug uccuuccucc      420

aacacucacg cugcgaaugc cgcccaaaaa aagaccgcac caaacccgaa aaaaaauccg      480

uacgcggcaa aggcaaaggc caaaaacgca aacgcaaaaa aucccgcuuc aaaucauggu      540

caguccacug cgaacccugc agcgaacgac gcaaacaccu cuucguccaa gacccacaaa      600

caugcaaaug cuccugcaaa aacacagacu cgcgcugcaa agcccgccaa cucgaacuaa      660

acgaacgcac cugccgcugc gacaaacccc gacgcuaggg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5412
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) 
       (opt11)

<400>  5412
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

ccgacgaaac cggcuucgaa cacuccggcc ucugggucuc cguccucgcc ggccuccucc      120

uaggcgcaug ccaagcccac cccauacccg acuccucacc ccuccuccaa uucggcggcc      180

aaguccgcca acgcuaccua uacaccgacg acgcccaaca aacagaagcc caccucgaaa      240

uccgagaaga cggcacaguc ggcggcgccg ccgaccaaag ccccgaaucc cuccuccaac      300

ucaaagcccu caaacccggc gucauccaaa uccucggcgu caaaacaucc cgcuuccuau      360

gccaacgccc cgacggcgcc cucuacggcu cacuccacuu cgaccccgaa gccugcuccu      420

uccgcgaacg ccuccucgaa gacggcuaca acgucuacca auccgaagcc cacggccuac      480

cccuacaccu ccccggcaac aaauccccuc accgcgaccc cgcaccccgc ggccccgccc      540

gcuuccuacc ccuccccggc cucccccccg cccuacccga accccccggc auccucgccc      600

cccaaccccc agacgucggc uccucugacc cccucuccau ggucggcggc ucccaaggcc      660

gcucacccuc cuacgaaucc uaaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5413
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt11)

<400>  5413
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

ggggaacaaa auuacuacca guccuacuac uccaacacgu ccuacuccac cuacuacuac      120

uccacgucgc aauccccuac gccgaaggac agaaaaagcg aagaaacaca cuacacgaau      180

uuaagaaauc agccaaaacc acccuaacca aagaagaccc ccuacugaaa aucaaaacua      240

agaaagucaa cuccgcagau gagugcgcaa accgaugcau acgcaaccgc ggcuucacau      300

ucacuugcaa agccuucguu uucgacaaau cacgaaaacg cugcuacugg uaccccuuua      360

acucgaugag cucaggcgug aagaaaggcu ucggccauga guucgaccua uacgaaaaua      420

aagauuacau acguaacugc aucaucggaa aagguggcag cuacaaaggc acugucucaa      480

uaacgaaaag uggcaucaaa ugccaacccu ggaacuccau gaucccucac gaacacucau      540

uccuccccuc cagcuacaga gggaaagacc uacaagaaaa cuacugccgu aauccaagag      600

gagaagaagg cggaccuugg ugcuucaccu ccaaccccga aguaagauac gaagugugcg      660

acauaccaca augcuccgaa gucgaaugca ugaccugcaa cggcgaaucc uaccgaggac      720

ccauggacca caccgaauca gguaagaccu gccaacgcug ggaccaacaa acaccccaca      780

gacacaaauu ccucccugaa cgcuaccccg acaaaggcuu cgacgacaac uacugcagga      840

acccagacgg uaaaccccga cccugguguu acacccucga cccagauaca cccugggaau      900

acugcgccau aaaaacaugc gcacacuccg ccgucaacga gacagacguc cccauggaaa      960

ccaccgagug cauacaagga caaggggaag gauacagagg aacaucaaac accauuugga     1020

acggcauacc cugccaaaga ugggacuccc aguaucccca caaacacgac aucacaccag     1080

aaaacuucaa augcaaggac cuacgagaaa acuacugccg caacccagac ggagcugaau     1140

cccccuggug cuucacaaca gacccgaaua uccgcgucgg auacuguucg caaaucccaa     1200

agugcgacgu cagcucagga caagacugcu acagaggaaa cggcaagaac uauaugggca     1260

accuuucgaa aacacgcagc ggccuaaccu gcuccaugug ggacaagaac auggaagacc     1320

uccaccggca cauauucugg gaacccgacg caaguaaacu uaacaaaaac uacugucgca     1380

auccggacga cgacgcccac ggcccuuggu gcuacaccgg uaacccccua aucccguggg     1440

acuacugccc cauaucccga ugcgaaggag auacaacacc caccaucgug aaccuagacc     1500

accccgucau cucaugcgcu aaaacgaaac agcuccgagu cgucaacggc aucccaacgc     1560

aaacgaccgu cggauggaug gucucccuga aauaccgcaa caaacacaua ugcggcggaa     1620

gccuaauaaa agaaagcugg guccuuacag cccggcaaug cuucccagcc cguaacaaag     1680

accucaaaga cuacgaagcc uggcucggca uccacgacgu acaugaacga ggggaagaaa     1740

aacgcaaaca aauacucaac aucucccagc ugguauacgg cccggaagga agcgaccucg     1800

uccucuugaa acuagccaga cccgccauac uagacaacuu cgucagcacc aucgaccucc     1860

ccucauacgg cugcaccauc ccagaaaaga caaccugcuc aaucuacggc uggggcuaca     1920

ccggacuaau caacgccgac ggacuccugc gggucgccca uuuguacauc augggaaacg     1980

aaaaaugcuc ccaacaccac caaggcaaag ucacccugaa cgaauccgaa cucugcgcag     2040

gcgccgagaa aaucggauca ggacccugcg aaggggacua cgggggcccc cucaucugcg     2100

agcaacauaa aaugcguaug gugcuaggcg ugaucguccc cggacgcgga ugcgccaucc     2160

cgaaccgccc cgggaucuuc guccgcgucg ccuacuacgc caaauggaua cauaaaguca     2220

uucucaccua caagcuguaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5414
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt11)

<400>  5414
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

aaggggaccc gaaaaagccg aggggaaaga ugucgagcua ugccuucuuc gugcaaacgu      120

gcagggagga acacaagaaa aagcacccgg acgcgagcgu gaacuucagc gaguucucga      180

aaaagugcuc ggaaaggugg aagaccauga gcgcgaaaga gaaagggaaa uuugaagaua      240

uggcgaaagc ggacaaggca agguacgagc gagagaugaa gacauauaua ccaccaaagg      300

gcgagaccaa gaaaaaguuc aaggacccga acgcgcccaa gcgcccgcca ucggccuuuu      360

ucuuguucug uagcgaguac aggcccaaga ucaagggaga gcacccgggc uugagcauag      420

gcgacgucgc gaaaaagcuc ggggaaaugu ggaauaacac ggccgcggac gauaaacagc      480

cauaugaaaa gaaagcggcc aagcuaaagg aaaaguacga gaaagauauc gcggcauauc      540

gcgcgaaagg gaaaccggac gcggccaaga aaggagucgu aaaagcggaa aagagcaaga      600

aaaagaaaga ggaagaggaa gaugaagagg acgaggaaga ugaagaggaa gaggaagaug      660

aagaggacga ggacgaggaa gaggacgaug acgaugaaua gggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5415
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt11)

<400>  5415
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuccuauc cuggguccac uggacacucg cccuccuccu cuaccuccac cacgccaaau      120

ggucccaagc agcacccacc acagaaggcg aacaaaaauc ccacgaaguc aucaaguuca      180

uggacgucua ccaacgcuca uacugccgcc ccaucgaaac acucguagac aucuuccaag      240

aauaccccga cgaaaucgaa uacaucuuca aacccuccug cgucccacua augcgcugcg      300

ccggaugcug caacgacgaa gcccucgaau gcgucccaac cuccgaaucc aacaucacca      360

ugcaaaucau gcgcaucaaa ccccaccaau cccaacacau cggcgaaaug uccuuccucc      420

aacacucccg cugcgaaugc cgccccaaaa aagaccgcac caaacccgaa aaaaaaucag      480

uccgcggcaa aggcaaaggu caaaaacgaa aacgcaaaaa aucacgcuuc aaauccuggu      540

ccguccacug cgaacccugc ucagaacgac gcaaacaccu cuucguccaa gacccccaaa      600

ccugcaaaug cucaugcaaa aacaccgacu cccgaugcaa agcccgccaa cucgaacuca      660

acgaacgaac cugccgcugc gacaaacccc gacgcuaagg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5416
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) 
       (opt12)

<400>  5416
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

cugacgaaac agguuucgaa cacucaggac uaugggucuc aguauuagca ggacuauuau      120

uaggagcaug ucaagcacau ccaauaccag acucaucacc acuacuacaa uucggcggac      180

aaguaagaca aagauacuua uacacagacg augcacaaca aacagaagca cauuuagaaa      240

uaagagaaga uggcacagua ggcggagcag cagaccaauc accagaauca cuauuacaau      300

uaaaagcauu aaaaccagga guaauacaaa uauuaggagu aaaaacauca agauucuuau      360

gucaaagacc ugacggagca cuauacggau cacuacacuu ugacccagaa gcaugcucau      420

uuagagaaag auuauuagaa gacggauaca auguauauca aucagaagca cacggauuac      480

cauuacacuu acccggaaau aaaucaccac auagagaccc agcaccaaga ggaccugcaa      540

gauuucuacc ucuaccagga cuaccaccag cacuaccuga accaccagga auauuagcac      600

cacaaccacc agacguagga uccucagacc ccuuaucaau gguaggcgga ucacaaggaa      660

gaucaccauc auaugaauca uaaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5417
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt12)

<400>  5417
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

ggggaacuaa auuacuacca guucuauuac uucaacacgu ccuauuacau uuauuacuau      120

uacacguugc aauaccauau gcagaaggac aaaaaaaaag aaggaacacc uuacacgaau      180

uuaaaaaauc ggcaaaaaca acccucacaa aggaagaccc acuauuaaaa aucaaaacaa      240

aaaaagugaa uagugcagac gaaugugcaa auagaugcau aagaaacaga ggauuuacau      300

ucacuuguaa agcauuugua uuugauaaau caaggaaaag guguuauugg uauccuuuua      360

acucaauguc uaguggagua aaaaaaggau ucggacauga auuugaccua uaugaaaaua      420

aagacuauau aagaaauugc auaauaggaa aagguggauc auauaaaggg acaguuagca      480

uaaccaaauc aggcauaaaa ugucaaccau ggaauucaau gauaccacau gaacauuccu      540

uucuaccuag uaguuaucgu ggaaaagauu uacaagaaaa uuauuguaga aacccaagag      600

gagaagaagg agggccaugg ugcuuuacaa gcaacccaga agucagauau gaaguaugug      660

acauaccaca auguucagaa guagaaugua ugacaugcaa uggagaaucg uauagagguc      720

caauggacca uacagaauca ggaaaaacau gucaaagaug ggaucaacaa accccacauc      780

gacauaaauu cuuaccagaa cgauauccag acaaaggguu cgacgauaau uauugcagaa      840

auccagaugg gaaaccaaga cccugguguu acacucuaga ccccgauaca ccaugggaau      900

auugugcaau aaaaacaugc gcacacucag caguaaauga gacugauguc ccaauggaaa      960

cuacagaaug cauucaagga caaggugaag guuaccgagg cacaaguaau acuauaugga     1020

augggauacc augucaaaga ugggacaguc aauacccaca uaaacaugau auaacgccag     1080

aaaauuuuaa auguaaagau uuaagagaaa auuauugcag aaauccugau ggcgcggaaa     1140

guccauggug cuucacaacu gauccuaaca uaagaguugg uuauugcagu caaauaccua     1200

aaugcgaugu aucauccgga caagauuguu auagggguaa uggaaaaaau uauaugggca     1260

auuuaucaaa aacacguagu ggauuaacau guucaaugug ggauaaaaau auggaagauu     1320

uacaucgaca cauuuucugg gaacccgaug cuaguaaauu aaacaaaaac uauugucgaa     1380

acccagauga ugaugcacau ggaccauggu gcuauacagg uaacccacuu auaccauggg     1440

acuauugucc uauaucaaga ugugaaggcg auacaacacc uacuauaguc aauuuagauc     1500

auccuguaau caguugcgcu aaaacaaaac aauuaagagu uguaaacgga auuccaacac     1560

aaacaacagu aggauggaug guaucacuca aauaccgaaa uaaacacaua ugcggagguu     1620

cuuuaauaaa agaaagcugg guauuaaccg caagacaaug cuucccggca agaaauaaag     1680

auuuaaaaga uuaugaagca ugguuaggaa uacacgaugu acacgaaagg ggagaagaaa     1740

aaagaaaaca aauacuaaau auaucacaau uaguauacgg cccagaaggg agcgaucuag     1800

uucuucuaaa auuagccaga ccagcaauau uagauaauuu uguaucuacu aucgaucuac     1860

caucauaugg auguacaaua ccugagaaaa caacauguuc aauauaugga uggggauaua     1920

cuggauuaau aaacgccgau ggacuucuua gaguagcaca cuuauauaua augggaaacg     1980

aaaaaugcuc acaacaucau caaggaaaag uuacacuaaa cgaaucagaa cuaugugcug     2040

gcgcagaaaa aaucggauca ggcccaugcg aaggugauua cggcggacca cuuauaugug     2100

aacaacauaa aaugcgcaug guauuaggag ucauaguucc cggucggggc ugugcgauac     2160

caaacagacc aggcauauuu guccguguag ccuacuaugc aaaauggaua cauaaaguaa     2220

uauuaacaua uaaauuauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5418
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt12)

<400>  5418
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

aaggagaccc aaaaaaacca agaggaaaaa ugucaagcua cgcauucuuc guacaaacau      120

gcagagaaga acacaaaaaa aaacacccag acgcaagcgu aaacuucagc gaauucagca      180

aaaaaugcuc agaaaggugg aaaacaauga gcgcaaaaga gaaaggaaaa uucgaagaca      240

uggcaaaagc agacaaagca agauacgaaa gagaaaugaa aacauacaua ccaccaaaag      300

gagaaacaaa aaaaaaauuu aaagacccaa acgcaccaaa aagaccacca ucagcauucu      360

uccuauucug cagugaauac agaccaaaaa uaaaaggaga acacccagga cuaagcauag      420

gagacguagc aaaaaaauua ggagaaaugu ggaacaacac agcagcagac gacaaacaac      480

cauacgaaaa aaaagcagca aaauuaaaag aaaaauacga aaaggacaua gcagcauauc      540

gagcaaaagg aaaaccagac gcagcaaaaa aaggaguagu aaaagcagaa aaaagcaaaa      600

aaaaaaaaga agaagaagaa gacgaagaag acgaagaaga cgaagaagaa gaagaagacg      660

aagaagacga agacgaagaa gaagacgacg acgacgaaua aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5419
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt12)

<400>  5419
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuacuauc auggguacac uggacacuag cauuacuacu auacuuacac cacgcaaaau      120

ggucacaagc agcaccaaca acagaaggag aacaaaaauc acacgaagua auaaaauuca      180

uggacguaua ccaacgauca uacugcagac caauagaaac acuaguagac auauuccaag      240

aauacccaga cgaaauagaa uacauauuca aaccaucaug cguaccauua augagaugcg      300

caggaugcug caacgacgaa gcauuagaau gcguaccaac aucagaauca aacauaacaa      360

ugcaaauaau gagaauaaaa ccacaccaau cacaacacau aggagaaaug ucauuccuac      420

aacauucaag augcgaaugc agaccaaaaa aagacagaac aaaaccagaa aaaaaaucag      480

uaagaggaaa aggaaaagga caaaaaagaa aaagaaaaaa aucaagauuc aaaucauggu      540

caguacacug cgaaccaugc ucagaacgaa gaaaacacuu auuuguacaa gacccacaaa      600

caugcaaaug cucaugcaaa aacacagacu caagaugcaa agcaagacaa cuagaacuaa      660

augaaagaac augcagaugu gacaaaccaa gacgauaagg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5420
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) 
       (opt13)

<400>  5420
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

cagacgaaac aggauuugaa cacucaggac uauggguauc aguacuagca ggauuauuac      120

uaggagccug ccaagcacac ccaauaccag acucaucacc auuauuacaa uucggaggac      180

aaguuagaca aagauaucua uauacagaug acgcacaaca aacagaagca cacuuagaaa      240

uaagagaaga cggaacagua ggaggagcag cagaccaauc accagaaucc cuacuacaau      300

uaaaagcacu aaaaccagga guaauacaaa uauuaggagu aaaaacauca agauuccuau      360

gccaaagacc agacggagca cuauacggcu cacuacacuu ugacccagaa gcaugcucau      420

ucagagaaag acuacuagaa gacggauaua auguauauca aucagaagca cacggacuac      480

cuuuacauuu accaggaaac aaaucaccac acagagaccc agcaccaaga ggcccagcac      540

gcuuuuuacc auuaccagga cuaccaccag cauuaccaga accaccagga auacuagcac      600

cacaaccacc agauguugga agcucagacc cacuaucaau gguaggagga ucacaaggaa      660

gaucaccauc auaugaauca uaaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5421
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt13)

<400>  5421
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaugu       60

ggggaacaaa acuuuuaccu guucuauuau uacaacacgu ccuguuacac uuauuauuac      120

uacauguagc cauaccuuac gcagaaggac aaaagaaacg aagaaacaca cuucaugaau      180

uuaagaaauc cgcaaaaaca acauuaacaa aagaagaucc auuauuaaaa auaaaaacaa      240

agaaaguuaa uucagcagau gaaugugcaa auagauguau aagaaacaga ggauuuaccu      300

uuacauguaa agcauuugua uucgacaaau caaggaaacg auguuacugg uauccauuca      360

auaguaugag uucuggagua aagaaaggau ucggucauga guucgaccua uaugaaaaua      420

aagacuauau uagaaauugu auaaucggca aagguggguc uuauaaaggc acuguuagua      480

uaacaaaauc aggaauaaaa ugucaaccau ggaauagcau gauaccacac gaacacucau      540

uucucccauc uucauacagg ggcaaagacc uacaagaaaa uuauuguaga aacccaaggg      600

gagaagaagg aggcccaugg uguuuuacau cgaauccuga aguacgauau gaaguaugug      660

acauccccca augcagugaa guagaaugua ugacuuguaa uggugaauca uaccgaggac      720

cuauggacca uacagaauca ggaaaaacuu gccaacgaug ggaucaacaa accccucauc      780

gacacaaauu uuuaccagaa cguuacccag auaaaggauu ugacgauaau uacuguagaa      840

auccagacgg uaaaccucga cccugguguu acacucuuga uccagauaca ccaugggaau      900

auugcgcaau aaaaacuugc gcacauucug caguaaauga aacagacguu ccaauggaaa      960

cuaccgaaug uauacaaggc caaggagaag gcuauagagg uacaucaaau acaauaugga     1020

auggcauacc cugccaaagg ugggacucuc aauauccaca uaaacaugau auaacaccag     1080

aaaacuuuaa auguaaagau uuaagagaaa auuacuguag aaauccggau ggagcagaau     1140

cucccuggug uuucacuacc gauccuaaca uaagaguagg auauuguagc caaauaccua     1200

aaugugaugu uagcucaggu caagacugcu acagagguaa uggcaaaaau uacaugggga     1260

aucucaguaa aacacguagu ggacucacau guucaaugug ggauaaaaau auggaagacc     1320

ugcacagaca uauauucugg gaaccugaug cuucaaaauu aaauaaaaau uauugcagaa     1380

auccagauga ugacgcucac ggaccauggu guuacacugg uaauccauua auaccauggg     1440

auuauugucc aauaucaaga ugcgaaggug auacaacucc aacaauagua aaucuagauc     1500

auccaguaau auccugugca aaaacaaaac aacuaagagu aguaaacgga auaccaacac     1560

aaacaacagu aggauggaug guuaguuuaa aauacagaaa uaaacauaua uguggaggau     1620

ccuuaauaaa agaaucaugg guauuaacug caagacaaug uuucccagca aggaacaaag     1680

auuuaaaaga uuacgaagca uggcuaggaa uacaugaugu ucacgaaaga ggagaagaaa     1740

aacguaaaca aauuuugaac auuucacaac uuguauacgg cccagaagga ucugauuuag     1800

uauuauuaaa guuagcaaga ccagcaauuc ucgauaauuu cguaucaacg auagaucucc     1860

ccaguuacgg cuguacgaua ccagaaaaga caacaugcag uauauacgga uggggauaua     1920

caggacuaau caacgcagau ggacuuuuaa gaguagccca cuuauauaua auggguaacg     1980

aaaaauguuc acaacaucau caaggaaaag uaacacuaaa ugaaagcgaa uuaugugcag     2040

gcgcagagaa aauaggaagc ggaccuugug aaggcgauua cgguggacca cuaauaugug     2100

aacaacauaa aaugagaaug guauuaggag uaauaguucc aggacgugga ugugccauac     2160

caaaccgacc aggaauauuu guuaggguag ccuacuacgc aaaauggauu cacaaaguaa     2220

uauuaacaua uaaacuauaa ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5422
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt13)

<400>  5422
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

aaggagaccc aaaaaaaccg agaggaaaaa ugagcagcua cgcauuuuuc guacaaacau      120

gcagagaaga acacaaaaaa aaacacccag acgcaagcgu aaacuuuagc gaauuuucaa      180

aaaaaugcuc agaaagaugg aaaacaauga gcgcaaaaga aaaaggaaaa uucgaagaca      240

uggcgaaagc agacaaagca agauaugaaa gagaaaugaa aacauacaua ccaccaaaag      300

gagaaaccaa aaaaaaauuu aaagacccaa acgcaccaaa aagaccacca agcgcauucu      360

uucuauucug cagugaauac agaccaaaaa uaaaaggaga acacccagga uuaagcauag      420

gagacguagc aaaaaaacua ggagaaaugu ggaacaacac agcagcagac gacaaacaac      480

cauacgaaaa aaaagcagca aaacuaaaag aaaaauacga aaaagacaua gcagcauaua      540

gagcaaaagg aaaaccagac gcagcaaaaa aaggaguagu aaaagcagaa aaaagcaaaa      600

aaaaaaaaga agaagaagaa gacgaagaag acgaagaaga cgaagaagaa gaagaagacg      660

aagaagacga agacgaagaa gaagacgacg acgacgaaua aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5423
<211>  1027
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt13)

<400>  5423
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuacuauc auggguacac uggacacuag cacuacuacu auacuuacac cacgcaaaau      120

ggagucaagc agcaccaaca acagaaggag aacaaaaaag ccacgaagua auaaaauuca      180

uggacguaua ucaacgauca uacugcagac caauagaaac acuaguagau aucuuccaag      240

aauacccaga cgaaauagaa uacauauuca aaccaucaug cguaccauua augagaugcg      300

caggaugcug caacgacgaa gcacuagaau gcguaccaac aucagaauca aacauaacaa      360

ugcaaauaau gagaauaaaa ccccaccaaa gccaacacau aggagaaaug ucauuccuac      420

aacacucaag augcgaaugc agacccaaaa aagaccgaac aaaaccagaa aaaaaaucag      480

uaagaggaaa aggaaaagga caaaaaagaa aacgaaaaaa aucacgauuc aaaucauggu      540

caguacacug cgaaccaugc ucugaaagaa gaaaacaccu auucguacaa gacccacaaa      600

cauguaaaug cagcugcaaa aacacagacu caagaugcaa agcaagacaa cuagaauuaa      660

acgaaagaac augcagaugc gacaaaccac gaagauaagg acuagugcau cacauuuaaa      720

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      780

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      840

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1020

cagaauu                                                               1027


<210>  5424
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (wt)

<400>  5424
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucggacg agaccggguu cgagcacuca ggacuguggg      120

uuucugugcu ggcuggucuu cugcugggag ccugccaggc acaccccauc ccugacucca      180

guccucuccu gcaauucggg ggccaagucc ggcagcggua ccucuacaca gaugaugccc      240

agcagacaga agcccaccug gagaucaggg aggaugggac gguggggggc gcugcugacc      300

agagccccga aagucuccug cagcugaaag ccuugaagcc gggaguuauu caaaucuugg      360

gagucaagac auccagguuc cugugccagc ggccagaugg ggcccuguau ggaucgcucc      420

acuuugaccc ugaggccugc agcuuccggg agcggcuucu ugaggacgga uacaauguuu      480

accaguccga agcccacggc cucccgcugc accugccagg gaacaagucc ccacaccggg      540

acccugcacc ccgaggacca gcucgcuucc ugccacuacc aggccugccc cccgcacucc      600

cggagccacc cggaauccug gccccccagc cccccgaugu gggcuccucg gacccucuga      660

gcaugguggg agguucccag ggccgaagcc ccagcuacga guccugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5425
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (wt)

<400>  5425
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucggacg agaccggguu cgagcacuca ggacuguggg      120

uuucugugcu ggcuggucuu cugcugggag ccugccaggc acaccccauc ccugacucca      180

guccucuccu gcaauucggg ggccaagucc ggcagcggua ccucuacaca gaugaugccc      240

agcagacaga agcccaccug gagaucaggg aggaugggac gguggggggc gcugcugacc      300

agagccccga aagucuccug cagcugaaag ccuugaagcc gggaguuauu caaaucuugg      360

gagucaagac auccagguuc cugugccagc ggccagaugg ggcccuguau ggaucgcucc      420

acuuugaccc ugaggccugc agcuuccggg agcggcuucu ugaggacgga uacaauguuu      480

accaguccga agcccacggc cucccgcugc accucccagg gaacaagucc ccacaccggg      540

acccugcacc ccgaggacca gcucgcuucc ugccacuacc aggccugccc cccgcacucc      600

cggagccacc cggaauccug gccccccagc cccccgaugu gggcuccucg gacccucuga      660

gcaugguggg agguucccag ggccgaagcc ccagcuacga guccugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5426
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (wt)

<400>  5426
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggga ccaaacuucu gccgguccug uugcugcagc      120

auguccuccu gcaccuccuc cugcuucaug ucgccauccc cuaugcagaa ggacagaaga      180

aaagaagaaa uacacuucau gaauuuaaaa agucagcaaa aacuacucuu accaaggaag      240

acccauuacu gaagauuaaa accaaaaaag ugaacucugc agaugagugu gccaacaggu      300

guaucaggaa caggggcuuu acguucacuu gcaaggccuu cguuuuugau aagucaagaa      360

aacgaugcua cugguauccu uucaauagua ugucaagugg agugaaaaaa ggguuuggcc      420

augaauuuga ccucuaugaa aacaaagacu auauuagaaa cugcaucauu gguaaaggag      480

gcagcuauaa agggacggua uccaucacua agaguggcau caaaugccag ccuuggaauu      540

ccaugauccc ccaugaacac agcuuuuugc cuucgagcua ucgcgguaaa gaccuacagg      600

aaaacuacug ucgaaauccu cgaggggaag aagggggacc cugguguuuc acaagcaauc      660

cagagguacg cuacgaaguc ugugacauuc cucaguguuc agaaguugaa ugcaugaccu      720

gcaaugguga aagcuacaga ggucccaugg aucacacaga aucaggcaag acuugucagc      780

gcugggacca gcagacacca caccggcaca aguucuugcc agaaagauau cccgacaagg      840

gcuuugauga uaauuauugc cgcaauccug auggcaagcc gaggccaugg ugcuacacuc      900

uugacccuga caccccuugg gaguauugug caauuaaaac gugcgcucac agugcuguga      960

augagacuga ugucccuaug gaaacaacug aaugcauuca aggccaagga gaagguuaca     1020

ggggaaccag caauaccauu uggaauggaa uucccuguca gcguugggau ucgcaguacc     1080

cucacaagca ugauaucacu cccgagaacu ucaaaugcaa ggaccuuaga gaaaauuauu     1140

gccgcaaucc agauggggcu gaaucaccau gguguuuuac cacugaccca aacauccgag     1200

uuggcuacug cucucaaauu cccaagugug acgugucaag uggacaagau uguuaucgug     1260

gcaaugggaa aaauuacaug ggcaacuuau ccaaaacaag gucuggacuu acauguucca     1320

ugugggacaa gaauauggag gauuuacacc gucauaucuu cugggagcca gaugcuagca     1380

aauugaauaa gaauuacugc cggaauccug augaugaugc ccauggaccu uggugcuaca     1440

cggggaaucc ucuuauuccu ugggauuauu gcccuauuuc ccguugugaa ggagauacua     1500

caccuacaau ugucaauuug gaccauccug uaauauccug ugccaaaaca aaacaacugc     1560

ggguuguaaa uggcauucca acacaaacaa caguagggug gaugguuagu uugaaauaca     1620

gaaauaaaca uaucugugga ggaucauuga uaaaggaaag uuggguucuu acugcaagac     1680

aauguuuucc agccagaaac aaagacuuga aagacuauga agcuuggcuu ggcauccacg     1740

auguucauga gagaggcgag gagaagcgca agcagaucuu aaacauuucc cagcuggucu     1800

augguccuga aggcucagac uugguuuuac ugaagcuugc ucgaccugca auccuggaua     1860

acuuugucag uacaauugau uuaccuaguu augguuguac aaucccugaa aagaccacuu     1920

gcaguauuua cggcuggggc uacacuggau ugaucaacgc ggaugguuua uuacgaguag     1980

cucaucugua uauuaugggg aaugagaaau gcagucagca ccaucaaggc aaggugacuu     2040

ugaaugaguc ugaguuaugu gcuggggcug aaaagauugg aucaggacca ugugagggag     2100

auuauggugg cccacucauu ugugaacaac acaaaaugag aaugguucuu ggugucauug     2160

uuccuggucg uggaugugcc aucccaaauc guccugguau uuuuguucga guagcauauu     2220

augcaaaaug gauacacaaa guaauuuuga cauacaaguu guaaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5427
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (wt)

<400>  5427
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggga ccaaacuucu gccgguccug uugcugcagc      120

auguccuccu gcaccuccuc cugcuucaug ucgccauccc cuaugcagaa ggacagaaga      180

aaagaagaaa uacacuucau gaauuuaaaa agucagcaaa aacuacucuu accaaggaag      240

acccauuacu gaagauuaaa accaaaaaag ugaacucugc agaugagugu gccaacaggu      300

guaucaggaa caggggcuuu acguucacuu gcaaggccuu cguuuuugau aagucaagaa      360

aacgaugcua cugguauccu uucaauagua ugucaagugg agugaaaaaa ggguuuggcc      420

augaauuuga ccucuaugaa aacaaagacu auauuagaaa cugcaucauu gguaaaggag      480

gcagcuauaa agggacggua uccaucacua agaguggcau caaaugccag ccuuggaacu      540

ccaugauccc ccaugaacac agcuuuuugc cuucgagcua ucgcgguaaa gaccuacagg      600

aaaacuacug ucgaaauccu cgaggggaag aagggggacc cugguguuuc acaagcaauc      660

cagagguacg cuacgaaguc ugugacauuc cucaguguuc agaaguugaa ugcaugaccu      720

gcaaugguga aagcuacaga ggucccaugg aucacacaga aucaggcaag acuugucagc      780

gcugggacca gcagacacca caccggcaca aguucuugcc agaaagauau cccgacaagg      840

gcuuugauga uaauuauugc cgcaauccug auggcaagcc gaggccaugg ugcuacacuc      900

uugacccuga caccccuugg gaguauugug caauuaaaac gugcgcucac agugcuguga      960

augagacuga ugucccuaug gaaacaacug aaugcauuca aggccaagga gaagguuaca     1020

ggggaaccag caauaccauu uggaauggaa uccccuguca gcguugggau ucgcaguacc     1080

cucacaagca ugauaucacu cccgagaacu ucaaaugcaa ggaccuuaga gaaaauuauu     1140

gccgcaaucc agauggggcu gaaucaccau gguguuuuac cacugaccca aacauccgag     1200

uuggcuacug cucucaaauu cccaagugug acgugucaag uggacaagau uguuaucgug     1260

gcaaugggaa aaauuacaug ggcaacuuau ccaaaacaag gucuggacuu acauguucca     1320

ugugggacaa gaauauggag gauuuacacc gucauaucuu cugggagcca gaugcuagca     1380

aauugaauaa gaauuacugc cggaauccug augaugaugc ccauggaccu uggugcuaca     1440

cggggaaucc ucuuauuccu ugggauuauu gcccuauuuc ccguugugaa ggagauacua     1500

caccuacaau ugucaauuug gaccauccug uaauauccug ugccaaaaca aaacaacugc     1560

ggguuguaaa uggcauucca acacaaacaa caguagggug gaugguuagu uugaaauaca     1620

gaaauaaaca uaucugugga ggaucauuga uaaaggaaag uuggguucuu acugcaagac     1680

aauguuuucc agccagaaac aaagacuuga aagacuauga agcauggcuu ggcauccacg     1740

auguucauga gagaggcgag gagaagcgca agcagaucuu aaacauuucc cagcuggucu     1800

augguccuga aggcucagac uugguuuuac ugaagcuggc ucgaccugca auccuggaua     1860

acuuugucag uacaauugau uuaccuaguu augguuguac aaucccugaa aagaccacuu     1920

gcaguauuua cggcuggggc uacacuggau ugaucaacgc ggaugguuua uuacgaguag     1980

cucaucugua uauuaugggg aaugagaaau gcagucagca ccaucaaggc aaggugacuu     2040

ugaaugaguc ugaguuaugu gcuggggcug aaaagauugg aucaggacca ugugagggag     2100

auuauggugg cccacucauu ugugaacaac acaaaaugag aaugguucuu ggugucauug     2160

uuccuggucg uggaugugcc aucccaaauc guccugguau uuuuguucga guagcauauu     2220

augcaaaaug gauacacaaa guaauuuuga cauacaaguu guaaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5428
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (wt)

<400>  5428
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaaggag auccuaagaa gccgagaggc aaaaugucau      120

cauaugcauu uuuugugcaa acuugucggg aggagcauaa gaagaagcac ccagaugcuu      180

cagucaacuu cucagaguuu ucuaagaagu gcucagagag guggaagacc augucugcua      240

aagagaaagg aaaauuugaa gauauggcaa aagcggacaa ggcccguuau gaaagagaaa      300

ugaaaaccua uaucccuccc aaaggggaga caaaaaagaa guucaaggau cccaaugcac      360

ccaagaggcc uccuucggcc uucuuccucu ucugcucuga guaucgccca aaaaucaaag      420

gagaacaucc uggccugucc auuggugaug uugcgaagaa acugggagag auguggaaua      480

acacugcugc agaugacaag cagccuuaug aaaagaaggc ugcgaagcug aaggaaaaau      540

acgaaaagga uauugcugca uaucgagcua aaggaaagcc ugaugcagca aaaaagggag      600

uugucaaggc ugaaaaaagc aagaaaaaga aggaagagga ggaagaugag gaagaugaag      660

aggaugagga ggaggaggaa gaugaagaag augaagauga agaagaagau gaugaugaug      720

aauaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5429
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (wt)

<400>  5429
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuucugc ucucuugggu gcacuggacc cuggcuuuac      120

ugcuguaccu ccaccaugcc aagugguccc aggcugcacc cacgacagaa ggagagcaga      180

agucccauga agugaucaag uucauggaug ucuaccagcg aagcuacugc cguccgauug      240

agacccuggu ggacaucuuc caggaguacc ccgacgagau agaguacauc uucaagccgu      300

ccugugugcc gcugaugcgc ugugcaggcu gcuguaacga ugaagcccug gagugcgugc      360

ccacgucaga gagcaacauc accaugcaga ucaugcggau caaaccucac caaagccagc      420

acauaggaga gaugagcuuc cuacagcaca gcagauguga augcagacca aagaaagaca      480

gaacaaagcc agaaaaaaaa ucaguucgag gaaagggaaa gggucaaaaa cgaaagcgca      540

agaaaucccg guuuaaaucc uggagcguuc acugugagcc uuguucagag cggagaaagc      600

auuuguuugu ccaagauccg cagacgugua aauguuccug caaaaacaca gacucgcguu      660

gcaaggcgag gcagcuugag uuaaacgaac guacuugcag augugacaag ccaaggcggu      720

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5430
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt1)

<400>  5430
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgacg agaccggcuu cgagcacucc gggcuguggg      120

ugagcguccu cgccggccug cugcucgggg ccugccaggc ccaccccauc ccggacucca      180

gcccccugcu gcaguucggc ggccaggugc gccagcggua ccucuacacc gacgacgccc      240

agcagacgga ggcccaccug gagauccgcg aggacgggac cgugggcggg gccgccgacc      300

agucccccga gagccugcuc cagcugaagg cgcugaagcc cggcgucauc cagauccucg      360

gggugaagac cucccgguuc cugugccagc gcccggacgg cgcccuguac gggagccucc      420

acuucgaccc cgaggccugc uccuuccggg agcgccugcu cgaggacggc uacaacgugu      480

accagagcga ggcccacggc cugccccugc accuccccgg gaacaagucc ccgcaccgcg      540

accccgcgcc ccggggcccc gcccgcuucc ugccgcugcc cgggcucccg cccgcccugc      600

ccgagccgcc cggcauccug gcgccccagc cgcccgacgu cggcagcucc gacccccuca      660

gcaugguggg gggcucccag ggccggagcc ccuccuacga gagcugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5431
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt1)

<400>  5431
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca ccaagcugcu ccccgugcug cugcuccagc      120

acguccugcu gcaccuccug cugcuccacg uggccauccc guacgccgag gggcagaaga      180

agcgccggaa cacccugcac gaguucaaga agagcgcgaa gacgacccug accaaggagg      240

acccccuccu gaagaucaag accaagaagg ugaacuccgc cgacgagugc gccaaccgcu      300

gcauccggaa ccgcggcuuc acguucaccu gcaaggccuu cgucuucgac aagagccgga      360

agcgcugcua cugguacccc uucaacucca ugagcuccgg ggugaagaag ggcuucgggc      420

acgaguucga ccuguacgag aacaaggacu acauccggaa cugcaucauc ggcaagggcg      480

ggagcuacaa gggcaccgug uccaucacca agagcgggau caagugccag cccuggaacu      540

ccaugauccc gcacgagcac agcuuccucc ccuccagcua ccgcggcaag gaccugcagg      600

agaacuacug ccggaacccc cgcggggagg agggcggccc cuggugcuuc acguccaacc      660

cggagguccg guacgaggug ugcgacaucc cccagugcag cgagguggag ugcaugaccu      720

gcaacgggga guccuaccgc ggccccaugg accacaccga gagcgggaag accugccagc      780

ggugggacca gcagacgccc caccgccaca aguuccugcc ggagcgguac cccgacaagg      840

gcuucgacga caacuacugc cgcaaccccg acggcaagcc ccggccgugg ugcuacaccc      900

ucgaccccga cacccccugg gaguacugcg ccaucaagac cugcgcgcac uccgccguca      960

acgagacgga cgugcccaug gagaccaccg agugcaucca ggggcagggc gagggguacc     1020

gcggcaccag caacacgauc uggaacggga ucccgugcca gcggugggac ucccaguacc     1080

cccacaagca cgacaucacc cccgagaacu ucaagugcaa ggaccugcgc gagaacuacu     1140

gccggaaccc cgacggcgcc gagagcccgu ggugcuucac caccgacccc aacauccgcg     1200

ugggcuacug cagccagauc cccaagugcg acgucuccag cgggcaggac ugcuaccgcg     1260

gcaacgggaa gaacuacaug ggcaaccugu ccaagacgcg gagcgggcuc accugcucca     1320

ugugggacaa gaacauggag gaccugcacc gccacaucuu cugggagccc gacgccagca     1380

agcugaacaa gaacuacugc cggaacccgg acgacgacgc gcacggcccc uggugcuaca     1440

ccggcaaccc ccucaucccg ugggacuacu gccccaucuc ccgcugcgag ggggacacca     1500

cgcccaccau cgugaaccug gaccaccccg ugaucagcug cgccaagacc aagcagcugc     1560

gggucgugaa cggcaucccg acccagacga ccguggggug gauggucucc cucaaguacc     1620

gcaacaagca caucugcggc gggagccuga ucaaggaguc cugggugcug accgcccggc     1680

agugcuuccc cgcccgcaac aaggaccuca aggacuacga ggccuggcug ggcauccacg     1740

acgugcacga gcggggcgag gagaagcgca agcagauccu gaacaucagc cagcucgucu     1800

acgggcccga gggcuccgac cuggugcugc ucaagcuggc gcggcccgcc auccuggaca     1860

acuucgugag caccaucgac cucccguccu acgggugcac gauccccgag aagaccaccu     1920

gcagcaucua cggcuggggc uacaccgggc ugaucaacgc cgacggccug cuccgcgucg     1980

cccaccugua caucaugggg aacgagaagu gcucccagca ccaccagggc aaggugaccc     2040

ugaacgagag cgagcucugc gccggggcgg agaagaucgg cuccggcccc ugcgaggggg     2100

acuacggcgg gccccugauc ugcgagcagc acaagaugcg gaugguccug ggcgugaucg     2160

ugccggggcg cggcugcgcc auccccaacc ggcccggcau cuucguccgc guggccuacu     2220

acgccaagug gauccacaag gugauccuga cguacaagcu cugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5432
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt1)

<400>  5432
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaggggg accccaagaa gccgcgcggc aagaugagca      120

gcuacgccuu cuucgugcag accugccggg aggagcacaa gaagaagcac cccgacgcca      180

gcgucaacuu cuccgaguuc agcaagaagu gcuccgagcg cuggaagacc augagcgcga      240

aggagaaggg gaaguucgag gacauggcca aggccgacaa ggcccgguac gagcgcgaga      300

ugaagacgua caucccgccc aagggcgaga ccaagaagaa guucaaggac cccaacgccc      360

ccaagcggcc gcccuccgcg uucuuccugu ucugcagcga guaccgcccc aagaucaagg      420

gggagcaccc cggccucucc aucggcgacg uggccaagaa gcugggggag auguggaaca      480

acaccgccgc cgacgacaag cagcccuacg agaagaaggc ggccaagcug aaggagaagu      540

acgagaagga caucgccgcc uaccgggcca agggcaagcc cgacgcggcc aagaaggggg      600

uggucaaggc cgagaagucc aagaagaaga aggaggagga ggaggacgag gaggacgagg      660

aggacgagga ggaggaggag gacgaggagg acgaggacga ggaggaggac gacgacgacg      720

agugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5433
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt1)

<400>  5433
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggacc cuggcccugc      120

uccuguaccu gcaccacgcg aaguggucgc aggccgcccc gacgaccgag ggcgagcaga      180

agagccacga ggucaucaag uucauggacg uguaccagcg gagcuacugc cgccccaucg      240

agacccucgu ggacaucuuc caggaguacc cggacgagau cgaguacauc uucaagccgu      300

cgugcguccc ccugaugcgg ugcgcggggu gcugcaacga cgaggcccug gagugcgugc      360

cgacgagcga gagcaacauc accaugcaga ucaugcggau caagccgcac cagucgcagc      420

acaucggcga gaugagcuuc cuccagcaca gccgcugcga gugccggccc aagaaggacc      480

ggaccaagcc ggagaagaag ucggugcgcg gcaaggggaa gggccagaag cggaagcgga      540

agaagagccg cuucaagagc uggucggucc acugcgagcc gugcagcgag cggcggaagc      600

accuguucgu gcaggacccc cagacgugca agugcagcug caagaacacc gacucgcgcu      660

gcaaggcccg gcagcuggag cucaacgagc ggaccugccg cugcgacaag ccgcggcggu      720

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5434
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt2)

<400>  5434
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg agaccggcuu cgagcacucc ggccucuggg      120

ucuccguccu cgccggccuc cuccucggcg ccugccaggc ccaccccauc cccgacuccu      180

ccccccuccu ccaguucggc ggccaggucc gccagcgcua ccucuacacc gacgacgccc      240

agcagaccga ggcccaccuc gagauccgcg aggacggcac cgucggcggc gccgccgacc      300

agucccccga gucccuccuc cagcucaagg cccucaagcc cggcgucauc cagauccucg      360

gcgucaagac cucccgcuuc cucugccagc gccccgacgg cgcccucuac ggcucccucc      420

acuucgaccc cgaggccugc uccuuccgcg agcgccuccu cgaggacggc uacaacgucu      480

accaguccga ggcccacggc cucccccucc accuccccgg caacaagucc ccccaccgcg      540

accccgcccc ccgcggcccc gcccgcuucc ucccccuccc cggccucccc cccgcccucc      600

ccgagccccc cggcauccuc gccccccagc cccccgacgu cggcuccucc gacccccucu      660

ccauggucgg cggcucccag ggccgcuccc ccuccuacga guccugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5435
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt2)

<400>  5435
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca ccaagcuccu ccccguccuc cuccuccagc      120

acguccuccu ccaccuccuc cuccuccacg ucgccauccc cuacgccgag ggccagaaga      180

agcgccgcaa cacccuccac gaguucaaga aguccgccaa gaccacccuc accaaggagg      240

acccccuccu caagaucaag accaagaagg ucaacuccgc cgacgagugc gccaaccgcu      300

gcauccgcaa ccgcggcuuc accuucaccu gcaaggccuu cgucuucgac aagucccgca      360

agcgcugcua cugguacccc uucaacucca uguccuccgg cgucaagaag ggcuucggcc      420

acgaguucga ccucuacgag aacaaggacu acauccgcaa cugcaucauc ggcaagggcg      480

gcuccuacaa gggcaccguc uccaucacca aguccggcau caagugccag cccuggaacu      540

ccaugauccc ccacgagcac uccuuccucc ccuccuccua ccgcggcaag gaccuccagg      600

agaacuacug ccgcaacccc cgcggcgagg agggcggccc cuggugcuuc accuccaacc      660

ccgagguccg cuacgagguc ugcgacaucc cccagugcuc cgaggucgag ugcaugaccu      720

gcaacggcga guccuaccgc ggccccaugg accacaccga guccggcaag accugccagc      780

gcugggacca gcagaccccc caccgccaca aguuccuccc cgagcgcuac cccgacaagg      840

gcuucgacga caacuacugc cgcaaccccg acggcaagcc ccgccccugg ugcuacaccc      900

ucgaccccga cacccccugg gaguacugcg ccaucaagac cugcgcccac uccgccguca      960

acgagaccga cguccccaug gagaccaccg agugcaucca gggccagggc gagggcuacc     1020

gcggcaccuc caacaccauc uggaacggca uccccugcca gcgcugggac ucccaguacc     1080

cccacaagca cgacaucacc cccgagaacu ucaagugcaa ggaccuccgc gagaacuacu     1140

gccgcaaccc cgacggcgcc gagucccccu ggugcuucac caccgacccc aacauccgcg     1200

ucggcuacug cucccagauc cccaagugcg acgucuccuc cggccaggac ugcuaccgcg     1260

gcaacggcaa gaacuacaug ggcaaccucu ccaagacccg cuccggccuc accugcucca     1320

ugugggacaa gaacauggag gaccuccacc gccacaucuu cugggagccc gacgccucca     1380

agcucaacaa gaacuacugc cgcaaccccg acgacgacgc ccacggcccc uggugcuaca     1440

ccggcaaccc ccucaucccc ugggacuacu gccccaucuc ccgcugcgag ggcgacacca     1500

cccccaccau cgucaaccuc gaccaccccg ucaucuccug cgccaagacc aagcagcucc     1560

gcgucgucaa cggcaucccc acccagacca ccgucggcug gauggucucc cucaaguacc     1620

gcaacaagca caucugcggc ggcucccuca ucaaggaguc cuggguccuc accgcccgcc     1680

agugcuuccc cgcccgcaac aaggaccuca aggacuacga ggccuggcuc ggcauccacg     1740

acguccacga gcgcggcgag gagaagcgca agcagauccu caacaucucc cagcucgucu     1800

acggccccga gggcuccgac cucguccucc ucaagcucgc ccgccccgcc auccucgaca     1860

acuucgucuc caccaucgac cuccccuccu acggcugcac cauccccgag aagaccaccu     1920

gcuccaucua cggcuggggc uacaccggcc ucaucaacgc cgacggccuc cuccgcgucg     1980

cccaccucua caucaugggc aacgagaagu gcucccagca ccaccagggc aaggucaccc     2040

ucaacgaguc cgagcucugc gccggcgccg agaagaucgg cuccggcccc ugcgagggcg     2100

acuacggcgg cccccucauc ugcgagcagc acaagaugcg caugguccuc ggcgucaucg     2160

uccccggccg cggcugcgcc auccccaacc gccccggcau cuucguccgc gucgccuacu     2220

acgccaagug gauccacaag gucauccuca ccuacaagcu cugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5436
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt2)

<400>  5436
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagggcg accccaagaa gccccgcggc aagauguccu      120

ccuacgccuu cuucguccag accugccgcg aggagcacaa gaagaagcac cccgacgccu      180

ccgucaacuu cuccgaguuc uccaagaagu gcuccgagcg cuggaagacc auguccgcca      240

aggagaaggg caaguucgag gacauggcca aggccgacaa ggcccgcuac gagcgcgaga      300

ugaagaccua cauccccccc aagggcgaga ccaagaagaa guucaaggac cccaacgccc      360

ccaagcgccc ccccuccgcc uucuuccucu ucugcuccga guaccgcccc aagaucaagg      420

gcgagcaccc cggccucucc aucggcgacg ucgccaagaa gcucggcgag auguggaaca      480

acaccgccgc cgacgacaag cagcccuacg agaagaaggc cgccaagcuc aaggagaagu      540

acgagaagga caucgccgcc uaccgcgcca agggcaagcc cgacgccgcc aagaagggcg      600

ucgucaaggc cgagaagucc aagaagaaga aggaggagga ggaggacgag gaggacgagg      660

aggacgagga ggaggaggag gacgaggagg acgaggacga ggaggaggac gacgacgacg      720

agugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5437
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt2)

<400>  5437
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc ucuccugggu ccacuggacc cucgcccucc      120

uccucuaccu ccaccacgcc aagugguccc aggccgcccc caccaccgag ggcgagcaga      180

agucccacga ggucaucaag uucauggacg ucuaccagcg cuccuacugc cgccccaucg      240

agacccucgu cgacaucuuc caggaguacc ccgacgagau cgaguacauc uucaagcccu      300

ccugcguccc ccucaugcgc ugcgccggcu gcugcaacga cgaggcccuc gagugcgucc      360

ccaccuccga guccaacauc accaugcaga ucaugcgcau caagccccac cagucccagc      420

acaucggcga gauguccuuc cuccagcacu cccgcugcga gugccgcccc aagaaggacc      480

gcaccaagcc cgagaagaag uccguccgcg gcaagggcaa gggccagaag cgcaagcgca      540

agaagucccg cuucaagucc ugguccgucc acugcgagcc cugcuccgag cgccgcaagc      600

accucuucgu ccaggacccc cagaccugca agugcuccug caagaacacc gacucccgcu      660

gcaaggcccg ccagcucgag cucaacgagc gcaccugccg cugcgacaag ccccgccgcu      720

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5438
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt3)

<400>  5438
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgaug agaccggcuu cgaacacucc gggcuguggg      120

ugucuguccu cgccggacuu cuguugggug cuugccaggc acaucccauc ccugacucaa      180

guccauuacu gcaauuuggc gggcagguua gacagaggua ccuauauaca gaugacgccc      240

agcaaacuga ggcgcaccuc gaaauucggg aggauggaac ggugggcggu gcugccgacc      300

agagcccgga aucccugcuu cagcugaagg cauugaaacc cgggguaaua cagauccucg      360

gagugaagac cucucgcuuc cugugucaac gaccugaugg cgcccuguac ggcucgcucc      420

auuuugaccc agaggcuugc ucauuccgug agagauuacu ggaagauggg uauaacgucu      480

accagagcga ggcacacgga cuucccuugc aucugccugg uaauaaaagu ccacacaggg      540

accccgcccc ucggggccca gcucgcuuuc uaccgcuccc cgggcugccu ccagcccuuc      600

ccgaaccucc aggcauucug gcgccccagc cgccugaugu gggauccucu gaccccuuga      660

gcaugguugg ugggucccag ggaagaucac caaguuauga gagcugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5439
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt3)

<400>  5439
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca ccaagcugcu ccccgugcuu cuguugcagc      120

acgucuuacu gcaucuacuc cugcuucacg uugccauccc uuacgcugag gggcaaaaga      180

agagaaggaa cacacugcau gaguucaaaa agagcgcaaa aacuacguug accaaggagg      240

acccacuccu gaagauuaaa acaaagaaag uaaauuccgc cgaugaaugc gcgaaccggu      300

guauacgcaa ucgaggauuu acuuuuaccu gcaaggcuuu cguguucgac aaaucucgua      360

agagauguua uugguacccg uuuaacucaa ugaguagcgg ugugaagaaa ggcuucgggc      420

acgaguuuga ucuguaugaa aauaaggacu acaucaggaa cugcauuauc ggaaaaggcg      480

guuccuauaa ggggacaguc ucuauuacca aaucgggaau caagugucag cccuggaacu      540

caaugauacc ucaugagcac agcuuccucc caaguuccua ccggggcaaa gauuuacagg      600

agaauuauug ccgcaauccc agaggcgaag aagggggacc uugguguuuu acuucuaacc      660

cagaagugag guacgagguu ugcgacaucc cccaguguag cgagguggaa ugcaugacau      720

guaaugguga guccuaccgg ggcccuaugg aucacaccga aucagggaag acgugccaac      780

gcugggacca gcagacucca caucgacaca aguuccugcc ggagagauau cccgauaaag      840

gauuugacga uaacuacugc aggaauccug acggcaagcc acggcccugg uguuauaccc      900

uugauccuga cacaccaugg gaauacugcg ccauuaaaac uugugcacau agugccguca      960

acgagaccga cgugcccaug gagacaaccg aaugcaucca gggucaaggg gagggauauc     1020

guggcacgag caauacuauu uggaacggca ucccguguca gcgcugggau ucucaguacc     1080

cucacaagca cgacauaaca cccgaaaacu ucaaaugcaa ggauuugaga gagaauuauu     1140

guaggaaccc agacggggcu gaauccccuu ggugcuuuac cacugauccc aauauucggg     1200

uaggauacug uucacagauc ccaaagugcg acguuagcag uggucaagau uguuaccgag     1260

gcaacgggaa aaauuauaug ggaaaccugu cuaagacacg cuccggccua accugcagca     1320

ugugggacaa aaauauggag gaucuccaua gacacauuuu cugggagccc gacgcaucga     1380

agcugaacaa aaauuacugc aggaacccug augacgacgc ccauggucca ugguguuaua     1440

cggggaaucc gcuuaucccc ugggauuacu gcccuaucuc ucggugugaa ggcgacacca     1500

caccaacuau ugugaaccug gaucaccccg ucauauccug cgcuaagacc aagcaguugc     1560

gcguggugaa uggaaucccu acacagacua ccgucggcug gaugguuuca cucaaauaua     1620

gaaacaagca uauuuguggg ggaagucuga ucaaagagag cuggguguua acagccaggc     1680

aaugcuuccc agcgcguaau aaggaccuga aagauuacga agcauggcuc gguauacacg     1740

acguacacga gcggggcgaa gagaagcgaa agcagauucu uaacaucucc cagcuggugu     1800

augggcccga gggaucugau uugguccuac ugaaacucgc cagaccggcu auccuggaca     1860

acuuugugag caccauugau cuuccuucau acggcuguac uaucccagaa aagacgacau     1920

gcaguauuua cgguuggggg uauaccggcc ugauaaaugc cgacggauug cucaggguug     1980

cacaucugua caucaugggc aacgagaaau guucccagca ccaucaaggg aaggugacuu     2040

uaaaugaaag cgagcugugc gcuggagccg agaaaauugg uucuggcccc ugugaagggg     2100

auuauggagg cccucuaauc ugcgagcagc acaagaugcg caugguccuc ggugugaucg     2160

uacccgggcg gggcugcgcg auuccaaaca gaccuggaau auucguuagg guggccuacu     2220

augcaaaaug gauccacaag gucauucuga ccuacaaacu uugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5440
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt3)

<400>  5440
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaggggg accccaaaaa gccuagagga aaaaugagcu      120

ccuacgccuu cuuugugcag accugcaggg aggaacacaa gaaaaagcau ccagaugcuu      180

cugucaacuu cucagaguuu aguaagaaau guagcgaacg guggaagaca auguccgcaa      240

aagagaaggg uaaauucgaa gacauggcca aggcggauaa ggcucgcuau gagcgagaga      300

ugaaaacuua caucccgccc aagggcgaaa cgaaaaagaa auuuaaggac ccuaaugccc      360

caaaacgucc cccuucugca uucuuucugu ucugcucgga guauagacca aagauuaagg      420

gggaacaccc cggacucuca auaggcgaug uugccaagaa acuuggugag auguggaaca      480

auaccgcugc agacgauaaa caaccuuacg agaagaaagc cgcuaagcug aaggaaaaau      540

augagaagga caucgccgcg uacagggcaa aagggaagcc agaugccgcu aaaaagggag      600

ugguaaaggc cgagaaaagc aagaaaaaga aagaagaaga ggaggacgaa gaggaugaag      660

aggacgaaga ggaggaagag gaugaagagg acgaagacga ggaggaagau gacgaugacg      720

agugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5441
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt3)

<400>  5441
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggacc cuugcccugu      120

uguuauaccu gcaucacgcu aagugguccc aggcagcccc cacaacugag ggcgaacaaa      180

aaucucauga ggucaucaag uuuauggacg uuuaucagag aucauacugc aggccuauug      240

aaacgcuagu ggauauauuc caggaguauc cagacgaaau cgaguacauu uuuaaaccga      300

guuguguacc ccucaugcgg ugcgcggggu guugcaauga ugaggcucug gaaugugugc      360

cuaccagcga guccaacauc acaaugcaga uuaugcgcau caagccacac caaucucagc      420

auauaggaga aaugucguuc cuucagcacu cacgaugcga gugucguccc aaaaaggaca      480

gaacuaagcc ugagaaaaag agcgucaggg guaaaggcaa ggggcagaaa cggaagcgca      540

agaaaaguag auuuaagucc uggucugugc acugcgaacc auguagcgag aggcggaaac      600

aucuguucgu ucaagauccc cagaccugca aguguuccug caaaaauaca gacucacgcu      660

gcaaggcccg acaguuggaa cucaacgaga gaaccuguag gugcgauaaa ccucggcguu      720

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5442
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt4)

<400>  5442
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgacg agaccggcuu cgagcacagc ggccuguggg      120

ugagcgugcu ggccggccug cugcugggcg ccugccaggc ccaccccauc cccgacagca      180

gcccccugcu gcaguucggc ggccagguga gacagagaua ccuguacacc gacgacgccc      240

agcagaccga ggcccaccug gagaucagag aggacggcac cgugggcggc gccgccgacc      300

agagccccga gagccugcug cagcugaagg cccugaagcc cggcgugauc cagauccugg      360

gcgugaagac cagcagauuc cugugccaga gacccgacgg cgcccuguac ggcagccugc      420

acuucgaccc cgaggccugc agcuucagag agagacugcu ggaggacggc uacaacgugu      480

accagagcga ggcccacggc cugccccugc accugcccgg caacaagagc ccccacagag      540

accccgcccc cagaggcccc gccagauucc ugccccugcc cggccugccc cccgcccugc      600

ccgagccccc cggcauccug gccccccagc cccccgacgu gggcagcagc gacccccuga      660

gcaugguggg cggcagccag ggcagaagcc ccagcuacga gagcugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5443
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt4)

<400>  5443
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca ccaagcugcu gcccgugcug cugcugcagc      120

acgugcugcu gcaccugcug cugcugcacg uggccauccc cuacgccgag ggccagaaga      180

agagaagaaa cacccugcac gaguucaaga agagcgccaa gaccacccug accaaggagg      240

acccccugcu gaagaucaag accaagaagg ugaacagcgc cgacgagugc gccaacagau      300

gcaucagaaa cagaggcuuc accuucaccu gcaaggccuu cguguucgac aagagcagaa      360

agagaugcua cugguacccc uucaacagca ugagcagcgg cgugaagaag ggcuucggcc      420

acgaguucga ccuguacgag aacaaggacu acaucagaaa cugcaucauc ggcaagggcg      480

gcagcuacaa gggcaccgug agcaucacca agagcggcau caagugccag cccuggaaca      540

gcaugauccc ccacgagcac agcuuccugc ccagcagcua cagaggcaag gaccugcagg      600

agaacuacug cagaaacccc agaggcgagg agggcggccc cuggugcuuc accagcaacc      660

ccgaggugag auacgaggug ugcgacaucc cccagugcag cgagguggag ugcaugaccu      720

gcaacggcga gagcuacaga ggccccaugg accacaccga gagcggcaag accugccaga      780

gaugggacca gcagaccccc cacagacaca aguuccugcc cgagagauac cccgacaagg      840

gcuucgacga caacuacugc agaaaccccg acggcaagcc cagacccugg ugcuacaccc      900

uggaccccga cacccccugg gaguacugcg ccaucaagac cugcgcccac agcgccguga      960

acgagaccga cgugcccaug gagaccaccg agugcaucca gggccagggc gagggcuaca     1020

gaggcaccag caacaccauc uggaacggca uccccugcca gagaugggac agccaguacc     1080

cccacaagca cgacaucacc cccgagaacu ucaagugcaa ggaccugaga gagaacuacu     1140

gcagaaaccc cgacggcgcc gagagccccu ggugcuucac caccgacccc aacaucagag     1200

ugggcuacug cagccagauc cccaagugcg acgugagcag cggccaggac ugcuacagag     1260

gcaacggcaa gaacuacaug ggcaaccuga gcaagaccag aagcggccug accugcagca     1320

ugugggacaa gaacauggag gaccugcaca gacacaucuu cugggagccc gacgccagca     1380

agcugaacaa gaacuacugc agaaaccccg acgacgacgc ccacggcccc uggugcuaca     1440

ccggcaaccc ccugaucccc ugggacuacu gccccaucag cagaugcgag ggcgacacca     1500

cccccaccau cgugaaccug gaccaccccg ugaucagcug cgccaagacc aagcagcuga     1560

gaguggugaa cggcaucccc acccagacca ccgugggcug gauggugagc cugaaguaca     1620

gaaacaagca caucugcggc ggcagccuga ucaaggagag cugggugcug accgccagac     1680

agugcuuccc cgccagaaac aaggaccuga aggacuacga ggccuggcug ggcauccacg     1740

acgugcacga gagaggcgag gagaagagaa agcagauccu gaacaucagc cagcuggugu     1800

acggccccga gggcagcgac cuggugcugc ugaagcuggc cagacccgcc auccuggaca     1860

acuucgugag caccaucgac cugcccagcu acggcugcac cauccccgag aagaccaccu     1920

gcagcaucua cggcuggggc uacaccggcc ugaucaacgc cgacggccug cugagagugg     1980

cccaccugua caucaugggc aacgagaagu gcagccagca ccaccagggc aaggugaccc     2040

ugaacgagag cgagcugugc gccggcgccg agaagaucgg cagcggcccc ugcgagggcg     2100

acuacggcgg cccccugauc ugcgagcagc acaagaugag aauggugcug ggcgugaucg     2160

ugcccggcag aggcugcgcc auccccaaca gacccggcau cuucgugaga guggccuacu     2220

acgccaagug gauccacaag gugauccuga ccuacaagcu gugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5444
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt4)

<400>  5444
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagggcg accccaagaa gcccagaggc aagaugagca      120

gcuacgccuu cuucgugcag accugcagag aggagcacaa gaagaagcac cccgacgcca      180

gcgugaacuu cagcgaguuc agcaagaagu gcagcgagag auggaagacc augagcgcca      240

aggagaaggg caaguucgag gacauggcca aggccgacaa ggccagauac gagagagaga      300

ugaagaccua cauccccccc aagggcgaga ccaagaagaa guucaaggac cccaacgccc      360

ccaagagacc ccccagcgcc uucuuccugu ucugcagcga guacagaccc aagaucaagg      420

gcgagcaccc cggccugagc aucggcgacg uggccaagaa gcugggcgag auguggaaca      480

acaccgccgc cgacgacaag cagcccuacg agaagaaggc cgccaagcug aaggagaagu      540

acgagaagga caucgccgcc uacagagcca agggcaagcc cgacgccgcc aagaagggcg      600

uggugaaggc cgagaagagc aagaagaaga aggaggagga ggaggacgag gaggacgagg      660

aggacgagga ggaggaggag gacgaggagg acgaggacga ggaggaggac gacgacgacg      720

agugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5445
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt4)

<400>  5445
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ugagcugggu gcacuggacc cuggcccugc      120

ugcuguaccu gcaccacgcc aaguggagcc aggccgcccc caccaccgag ggcgagcaga      180

agagccacga ggugaucaag uucauggacg uguaccagag aagcuacugc agacccaucg      240

agacccuggu ggacaucuuc caggaguacc ccgacgagau cgaguacauc uucaagccca      300

gcugcgugcc ccugaugaga ugcgccggcu gcugcaacga cgaggcccug gagugcgugc      360

ccaccagcga gagcaacauc accaugcaga ucaugagaau caagccccac cagagccagc      420

acaucggcga gaugagcuuc cugcagcaca gcagaugcga gugcagaccc aagaaggaca      480

gaaccaagcc cgagaagaag agcgugagag gcaagggcaa gggccagaag agaaagagaa      540

agaagagcag auucaagagc uggagcgugc acugcgagcc cugcagcgag agaagaaagc      600

accuguucgu gcaggacccc cagaccugca agugcagcug caagaacacc gacagcagau      660

gcaaggccag acagcuggag cugaacgaga gaaccugcag augcgacaag cccagaagau      720

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5446
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt5)

<400>  5446
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgaug agaccggcuu cgaacacucc gggcuguggg      120

ugucuguccu cgccggacug cuucugggcg cuugccaggc ccaucccauc ccugacagcu      180

ccccgcuccu gcaauuuggg ggacagguua gacagcggua ccuuuauaca gaugacgcgc      240

agcaaacgga ggcucaccug gaaauucgcg aggauggcac cgugggcgga gccgccgacc      300

agucucccga aagccuccug cagcugaagg cucucaaacc uggcgugauc cagauucugg      360

gcgucaagac auccagauuc cuuugucaac ggcccgaugg ggcccuguac ggaucucucc      420

auuuugaccc ugaggcuugc agcuuccgcg agagacugcu ugaagauggc uauaacgugu      480

accaguccga ggcccacggg cugccccucc aucugccugg aaauaaaagc ccgcaccggg      540

accccgcgcc ucgcggcccc gccagauuuc ugccucuccc cgggcugccg ccugcccuuc      600

ccgaaccucc cggaauccug gcuccccagc cuccggaugu ugggucuucc gacccccuca      660

gcaugguggg cgggucucag ggacgguccc cuagcuauga gucuugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5447
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt5)

<400>  5447
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca ccaagcugcu ccccgugcug cuucugcagc      120

acguccuccu gcaucuucug cuccugcacg uugccauccc uuacgcugag gggcagaaaa      180

agagacggaa cacacugcau gaguucaaaa agagcgccaa aacgacccuc acaaaggaag      240

acccgcugcu uaagauuaaa accaagaaag ucaauuccgc ggaugaaugc gcuaaccgcu      300

guaucagaaa ucggggauuu acauuuaccu gcaaggccuu cguguucgac aaaucucgca      360

agagauguua uugguacccc uuuaacagca uguccucugg cgugaagaaa ggguucggac      420

acgaguuuga ucuguaugaa aauaaggacu acauucggaa cugcaucauu ggcaaagggg      480

gaagcuauaa gggcacagug uccaucacca aaucuggcau caagugucaa ccuuggaaua      540

gcaugauucc ccaugagcac uccuuccucc cuagcucuua ccgcgggaaa gaucugcagg      600

agaacuauug cagaaauccc cggggagaag agggcgggcc uugguguuuu acguccaacc      660

cggaaguucg cuacgaggug ugcgacaucc cccaguguag cgaggucgaa ugcaugaccu      720

guaauggaga gucuuacaga ggcccuaugg aucacacaga auccgggaag accugccaac      780

ggugggacca gcagacaccc caucgccaca aguuccuucc ugagagauau cccgauaaag      840

gauuugacga uaacuacugc cggaauccgg acggcaagcc ucgccccugg uguuauaccc      900

uggauccuga cacgcccugg gaauacugcg ccauuaaaac augugcucau agcgccguga      960

acgagaccga cguucccaug gagacaaccg aaugcaucca gggccaaggg gagggauaua     1020

gaggcaccuc uaauacaauu uggaacggga ucccuuguca gcggugggau ucccaguacc     1080

cgcacaagca cgacauuacg cccgaaaacu ucaaaugcaa ggaucucaga gagaauuauu     1140

gucgcaaccc ugacggagcu gaaagccccu ggugcuuuac cacagauccu aauauccggg     1200

ugggcuacug uucccagauc cccaagugcg acgucucuag cgggcaagau uguuacagag     1260

gaaacggcaa aaauuauaug ggcaaccugu ccaagacccg cagcgggcug acaugcucua     1320

ugugggacaa aaauauggag gaucuccauc ggcacauuuu cugggagccg gacgccucca     1380

agcugaacaa aaauuacugc agaaacccug augacgacgc gcauggaccc ugguguuaua     1440

ccggcaaucc ucuuaucccc ugggauuacu gcccuauuag ccgcugugaa ggggacacga     1500

cacccaccau cgugaaccug gaucacccgg ugauuucuug cgccaagacc aagcagcucc     1560

gggucguuaa uggaaucccu acacagacca cagugggcug gauggugagc cugaaauaua     1620

gaaacaagca uaucuguggg ggcucccuua uuaaagaguc uuggguccug acggcucgcc     1680

aaugcuuccc cgcccggaau aaggaccuca aagauuacga ggcuuggcug ggaauccacg     1740

acgugcacga aagaggcgaa gagaagcgca agcagauucu gaacaucagc cagcucguuu     1800

augggcccga gggauccgau cuggugcuuc ugaaacucgc ccggccugcg auucuggaca     1860

acuuugucag caccaucgau cuuccgucuu acggcuguac aauccccgaa aagaccacau     1920

gcuccauuua cgggugggga uauaccggcc ugaucaaugc cgacgggcuc cugagagugg     1980

cucaucugua cauuaugggc aacgagaaau guagccagca ccaucaagga aagguuacgc     2040

ucaaugaauc ugagcugugc gccggcgcug agaaaaucgg guccggaccu ugugaaggcg     2100

auuauggggg accccuuauu ugcgagcagc acaagaugcg gauggugcug ggcgucaucg     2160

ugccugggcg cggcugcgcc auucccaaca gaccuggaau cuucguccgg guggccuacu     2220

augcuaaaug gauccacaag guuauucuca ccuacaagcu gugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5448
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt5)

<400>  5448
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaggggg accccaaaaa gccuagagga aaaaugagcu      120

ccuacgccuu cuuugugcag accugccggg aggaacacaa gaaaaagcau ccggaugcuu      180

cugucaacuu cagcgaguuu uccaagaaau guucugaacg cuggaagaca augagcgcca      240

aagagaaggg caaauucgaa gacauggcga aggcugauaa ggccagauau gagcgggaga      300

ugaaaacgua cauucccccu aagggggaaa ccaaaaagaa auuuaaggac cccaaugccc      360

cuaaaagacc cccuuccgcu uucuuucugu ucugcucuga guaucgcccg aagaucaagg      420

gagaacaccc cggccucagc aucggggaug uugccaaaaa gcugggagag auguggaaca      480

auacagcugc cgacgauaaa caaccuuacg agaagaaagc ggccaaacuu aaggaaaagu      540

augagaagga cauugcugcc uaccgggcua aaggcaagcc cgaugccgcg aaaaagggcg      600

uggugaaggc cgaaaaaucc aagaaaaaga aagaggaaga ggaggacgaa gaggaugaag      660

aggacgaaga ggaggaagag gaugaagagg acgaagacga ggaggaagau gacgaugacg      720

agugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5449
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt5)

<400>  5449
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggacc cuggcccuuc      120

ugcucuaccu gcaucacgcu aagugguccc aggccgcgcc cacaacggag ggcgaacaaa      180

aaucucauga ggucaucaag uuuauggacg uuuaucagag aagcuacugc cggccuauug      240

aaacccuugu ggauaucuuc caggaguauc cggacgaaau ugaguacauc uuuaaacccu      300

ccugugugcc ucugaugcgc ugcgcugggu guugcaauga ugaggcccuc gaaugugucc      360

ccacaucuga gagcaacauu accaugcaga ucaugagaau caagccucac caaucccagc      420

auauuggaga aaugucuuuc cugcagcaca gccggugcga gugucgcccc aaaaaggaca      480

gaacaaagcc ugagaaaaag uccgugcggg gcaaagggaa gggacagaaa cgcaagagaa      540

agaaaagccg guuuaagucu ugguccguuc acugcgaacc guguagcgag cgcagaaaac      600

aucuguucgu gcaagauccc cagaccugca aguguucuug caaaaauaca gacucccggu      660

gcaaggcccg ccagcucgaa cugaacgaga gaaccugucg gugcgauaaa ccucgcagau      720

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5450
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt6)

<400>  5450
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gauucagaug aaacaggauu ugaacacuca ggauuauggg      120

ucucaguuuu agcaggacua uuacuaggag caugucaagc acauccaaua ccagacucaa      180

gcccauuauu acaauuugga ggacaaguaa gacaaagaua uuuauauaca gaugacgcac      240

aacaaacaga agcacauuua gaaauaagag aagacggcac aguaggagga gcagcagauc      300

aaucaccaga aucacuauua caauuaaaag cauuaaaacc aggaguaaua caaauauuag      360

gaguaaaaac aucaagauuc uuaugccaaa gaccugacgg agcauuauau gguucacuac      420

acuuugaccc agaagcaugu ucauucagag aaagacuacu agaagacgga uauaauguuu      480

accaaucuga agcacaugga uuaccacuac acuuaccagg aaauaaauca ccacaccgag      540

acccagcacc acgaggacca gcaagauucc uaccacuacc aggauuacca ccagcauuac      600

cagaaccacc aggaauacua gcuccacaac caccagacgu aggauccuca gauccauuau      660

caaugguagg aggaucucaa gguagaaguc ccucauacga aucauaagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5451
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt6)

<400>  5451
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggaa caaaacuauu accaguauua uuauuacaac      120

augucuuauu acauuuacuu cuacuacaug uugcaauacc cuaugccgaa ggacaaaaga      180

aaagaagaaa cacucuucac gaguucaaga aaagcgcaaa aacaacauua acaaaagaag      240

acccacuacu aaaaauaaaa acaaagaaag uaaacucagc agaugaaugu gccaacagau      300

guauuagaaa ccgggguuuu acuuuuacau gcaaagccuu cguauucgau aaaucaagga      360

aaagaugcua cugguaucca uucaauucaa ugucauccgg agucaagaaa ggauucggcc      420

augaauuuga ccuauacgaa aauaaagauu auaucagaaa cuguauaaua ggaaaaggug      480

guucauacaa aggaacagua ucaauaacaa aaagcgguau uaaaugucaa cccuggaacu      540

cuaugauucc ucaugaacau ucauuuuuac caucaucaua cagagguaaa gacuuacaag      600

aaaauuacug cagaaaucca aggggagaag aaggcggacc auggugcuuu acaucaaauc      660

ccgaaguaag auaugaagua ugcgacauac cacaauguag ugaaguugaa uguaugacau      720

guaauggaga aagcuacaga gguccaaugg aucauacaga aucaggaaaa acaugccaaa      780

gaugggauca acaaacaccg cauagacaua aauuuuuacc agaaagauau ccagauaaag      840

gauucgauga caauuacugu aggaaucccg acggaaaacc acgaccaugg ugcuauacac      900

uagacccuga uacuccaugg gaauauugcg cuauaaaaac uugugcacau ucagcaguaa      960

acgaaaccga cguaccaaug gaaaccacug aauguauaca agggcaagga gaaggauaca     1020

gaggaacauc aaauacaaua uggaacggaa uacccuguca aagaugggau agccaauauc     1080

cacauaaaca cgacauaacc ccagaaaacu uuaaauguaa agaucuaaga gaaaauuacu     1140

gcagaaaucc cgauggcgca gaaucaccau ggugcuucac aacagauccc aacauaagag     1200

ucggauauug cucccagauu ccuaaaugug auguaagcuc cgggcaagac ugcuaccgag     1260

gcaacgguaa aaauuacaug ggaaacuuaa guaaaacaag aucaggauua acaugcagua     1320

ugugggauaa aaauauggag gacuuacaua gacauauauu cugggaacca gaugcaucaa     1380

aacuuaacaa aaauuauugc agaaacccag acgacgaugc acacggacca ugguguuaua     1440

caggaaaucc acuuauacca ugggacuauu guccaauauc acgaugcgaa ggagauacaa     1500

caccaacaau aguaaacuua gaucauccag uaauaaguug cgcaaaaacu aaacaauuac     1560

gaguuguuaa cggaauacca acacaaacua cagucggaug gaugguuuca uuaaaauaua     1620

gaaacaaaca cauaugcgga ggaucccuua uaaaagaauc cuggguauua acagcaagac     1680

aauguuuucc agccagaaau aaagaucuca aagacuacga agcaugguua ggcauacacg     1740

auguacauga acgaggagaa gaaaaacgaa aacaaauauu aaauauaagc cagcuaguuu     1800

auggaccaga aggaucggac uuaguacuau uaaaacuugc aagaccagca auccuagaca     1860

auuuugucuc aacaaucgac uuacccucau auggaugcac uauuccggag aaaacaacau     1920

gcuccauaua cggaugggga uauacaggau ugauaaaugc agauggauua cuaagaguag     1980

cacaucuaua cauaauggga aaugaaaaau guucacaaca ccaucaagga aaaguaacac     2040

uaaacgaaag cgaauuaugu gcaggcgcag agaaaauagg caguggacca ugugaaggag     2100

auuacggugg accacuaaua ugcgaacaac auaaaaugag aaugguccua ggaguaauag     2160

uccccggaag aggaugugca auaccaaauc gaccgggcau auuuguaaga guagcauacu     2220

acgcaaaaug gauacacaaa guaauacuaa cauacaaacu auaaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5452
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt6)

<400>  5452
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaggag acccaaaaaa accaagagga aaaaugucaa      120

gcuacgcauu cuucguacaa acaugcagag aagaacacaa aaaaaaacac ccagacgcaa      180

gcguaaacuu cagcgaauuc agcaaaaaau guucagaaag auggaaaaca augagcgcaa      240

aagaaaaagg aaaauucgaa gacauggcaa aagcagacaa agcaagauac gaaagagaaa      300

ugaaaacaua cauaccacca aaaggagaaa caaaaaaaaa auucaaagac ccaaacgcgc      360

caaaaagacc accaucagca uucuucuuau ucugcaguga auacagacca aaaauaaaag      420

gagaacaccc aggacuaagu auaggagacg uagcaaaaaa acuaggagaa auguggaaca      480

acacagcagc agacgacaaa caaccauacg aaaaaaaagc agcaaaacua aaagaaaaau      540

acgaaaaaga cauagcggca uacagagcaa aaggaaaacc agacgcagca aaaaaaggag      600

uaguaaaagc agaaaaaagu aaaaaaaaaa aagaagaaga agaagacgaa gaagacgaag      660

aagacgaaga agaagaagaa gacgaagaag acgaagacga agaagaagac gacgacgacg      720

aauaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5453
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt6)

<400>  5453
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuau uaagcugggu acacuggaca cuagcacuac      120

uacuauacuu acaccacgcc aaauggagcc aagcagcacc aacaacagaa ggagaacaaa      180

aaucacacga aguaauaaaa uucauggacg uauaccaaag aucauacugu agaccaauag      240

aaacacuagu agacauauuc caagaauacc cagacgaaau agaauacaua uucaaaccau      300

caugcguacc acuaaugaga ugcgcaggau gcugcaacga cgaagcacua gaaugcguac      360

caacaucaga aucaaacaua acaaugcaaa uaaugagaau aaaaccacac caaagucaac      420

acauaggaga aaugaguuuc cuacaacacu caagaugcga augcagacca aaaaaagaca      480

gaacaaaacc agaaaaaaaa ucaguaagag gaaaaggaaa aggccaaaaa agaaaaagaa      540

aaaaaucaag auucaaaagc uggucaguac acugugaacc auguucagaa agaagaaaac      600

accuauucgu acaagaccca caaacaugca aaugcaguug caaaaacaca gacucaagau      660

gcaaagcaag acaacuagaa uuaaaugaac gaacaugcag augcgacaaa ccaagaagau      720

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5454
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt7)

<400>  5454
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgaug agaccggcuu cgaacacucc gggcuguggg      120

ugaguguccu cgccggucug uugcugggcg caugccaggc ccaucccauc ccagacagcu      180

ccccgcuccu gcaauuuggg ggccagguga ggcagcggua cuuguauacu gaugacgcgc      240

agcaaaccga ggcccaccug gaaauucgcg aggaugguac gguagggggc gcagccgacc      300

agagucccga aagccuccug cagcugaagg cacucaaacc aggcgugauc cagauucugg      360

gggucaagac uuccagguuc uugugucaac ggcccgaugg ugcccuguac ggcagccucc      420

auuuugaccc agaggcgugc uccuuccgcg agaggcugcu ggaagauggg uauaacgugu      480

accagaguga ggcccacggc uugccccucc aucugccagg uaauaaaagc ccgcaccggg      540

accccgcacc acgcgggccc gccagguuuc ugccacuccc cggccugccg cccgccuugc      600

cagaaccccc aggcauccug gcaccccagc caccggaugu gggguccagc gacccccuca      660

guauggucgg uggcucccag gggcggagcc cauccuauga gaguugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5455
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt7)

<400>  5455
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca ccaagcugcu ccccgugcug uugcugcagc      120

acguccuccu gcauuugcug cuccugcacg uggccauccc auacgcagag gggcagaaaa      180

agaggcggaa cacucugcau gaguucaaaa agagcgccaa aaccacgcuc acuaaggagg      240

acccgcuguu gaagauuaaa accaagaaag uaaauuccgc ggaugaaugc gccaaccgcu      300

guaucaggaa ucgggguuuu accuucacuu gcaaggcauu uguguucgac aaaagucgca      360

agagguguua uugguacccc uuuaacagca uguccagugg cgucaaaaag ggguucggcc      420

acgaguuuga ucuguaugaa aauaaggacu acauucggaa cugcaucauu gguaaagggg      480

gcagcuauaa gggcaccgug uccaucacga aaagcgggau caagugucaa ccauggaacu      540

ccaugauucc ccaugagcac aguuuccucc caagcuccua ccgcgguaaa gaucugcagg      600

agaauuauug caggaauccc cggggcgaag aagggggccc augguguuuu acuagcaacc      660

cggaagugcg cuacgagguc ugcgacaucc cccaguguag ugagguggaa ugcaugaccu      720

gcaaugguga guccuacagg gggccaaugg aucacacuga aagcggcaag accugucaac      780

ggugggacca gcagacuccc caucgccaca aguuccugcc agagagguau cccgauaaag      840

gcuuugacga uaacuacugc cggaauccgg acgggaagcc ccgcccaugg uguuauacgu      900

uggaucccga cacuccaugg gaauacugcg ccauuaaaac cugugcacau uccgccguaa      960

acgagacuga cgugcccaug gagaccaccg aaugcaucca gggucaaggc gagggguaua     1020

ggggcaccag uaauacgauu uggaacggua ucccauguca gcggugggau agccaguacc     1080

cgcacaagca cgacauuacc cccgaaaacu ucaaaugcaa ggaucuccgc gagaauuauu     1140

guaggaaccc agacggcgcg gaaucccccu ggugcuucac uaccgaucca aauauccggg     1200

ucggguacug cagccagauc cccaagugug acgugaguuc cggccaagau ugcuacaggg     1260

ggaacgguaa aaauuauaug ggcaaccuga gcaagacccg cagugggcug acuuguucca     1320

ugugggacaa aaauauggag gaucuccauc ggcacaucuu uugggagccg gacgccagca     1380

agcugaacaa aaauuacugc aggaacccag augacgacgc acauggcccc ugguguuaua     1440

cggguaaucc cuugauucca ugggauuacu gccccauuag ccgcugugaa ggcgacacca     1500

cuccaaccau cgugaaccug gaucacccgg ucauuuccug cgccaagacc aagcagcucc     1560

gggugguaaa ugggaucccc acucagacga ccgugggcug gauggucagu cugaaauaua     1620

ggaacaagca uaucuguggg ggcagccuga uuaaagaguc cuggguguug acugcccgcc     1680

aaugcuuccc agcacggaau aaggaccuca aagauuacga agccuggcug gguauccacg     1740

acgugcacga gaggggcgaa gagaagcgga aacagauucu gaacaucagc cagcucgucu     1800

augggcccga ggguagugau cugguguugc ugaagcucgc gcgcccagcc auucuggaca     1860

acuuuguauc caccaucgau cugcccagcu acggcuguac uaucccggaa aagaccacgu     1920

gcuccauuua cggguggggc uauaccgggu ugaucaaugc agacggccuc cugagggugg     1980

cccaucugua cauuaugggu aacgagaaau gcagucagca ccaucaaggg aaggucacuc     2040

ucaaugaaag cgagcugugu gcaggcgccg agaaaaucgg cuccgggcca ugcgaaggug     2100

auuauggcgg gcccuugauu ugugagcagc acaagaugcg gauggugcug ggcgucaucg     2160

ugccaggucg cgggugcgcc auucccaaca ggccgggcau cuucgugcgg guagcguacu     2220

augcaaaaug gauccacaag gugauucuca ccuacaagcu gugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5456
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt7)

<400>  5456
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaggggg accccaaaaa gccaaggggu aaaaugagcu      120

ccuacgccuu cuuugugcag accugccggg aggaacacaa gaaaaagcau ccggaugcaa      180

gugucaacuu cagcgaguuu uccaagaaau guagugaacg cuggaagacu augagcgcca      240

aagagaaggg caaauucgaa gacauggcga aggccgauaa agcaagguau gagcgggaga      300

ugaagaccua cauuccccca aagggggaaa cgaaaaagaa auuuaaggac cccaaugccc      360

caaaaaggcc cccauccgca uucuuucugu ucugcagcga guaucgcccg aagaucaagg      420

gcgaacaccc cggucucucc aucggggaug uggccaaaaa gcugggcgag auguggaaca      480

auacugcggc cgacgauaaa caaccauacg agaagaaagc agccaaguug aaggaaaaau      540

augagaagga cauugccgca uaccgggcca aaggcaagcc cgaugcggcc aaaaaggggg      600

uagugaaggc agagaaaagu aagaaaaaga aagaagaaga ggaggacgaa gaggaugaag      660

aggacgaaga ggaggaagag gaugaagagg acgaagacga ggaggaagau gacgaugacg      720

agugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5457
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt7)

<400>  5457
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggacc cuggccuugc      120

ugcucuaccu gcaucacgca aagugguccc aggccgcgcc cacuaccgag ggcgaacaga      180

aaagucauga ggucaucaag uuuauggacg uguaucaaag gagcuacugc cggccaauug      240

aaacguuggu agauaucuuc caggaguauc cggacgaaau ugaguacauc uuuaaacccu      300

ccugugugcc acugaugcgc ugcgccgggu guugcaauga ugaggcacuc gaaugugucc      360

ccaccaguga gagcaacauu acuaugcaga ucaugaggau caagccacac caaucccagc      420

auauugguga aaugagcuuc cugcagcacu cccggugcga gugucgcccc aaaaaggaca      480

ggaccaagcc agagaaaaag agugugcggg gcaaagggaa gggccagaaa cgcaagagga      540

aaaagagccg guuuaagucc uggagcgugc acugcgaacc guguagugag cgcaggaaac      600

aucuguucgu ccaagauccc cagacuugca agugcuccug uaaaaauacc gacagccggu      660

gcaaggcccg ccagcucgaa cugaacgaga ggacgugucg gugcgauaaa ccaaggcgcu      720

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5458
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt8)

<400>  5458
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucugacg aaaccggcuu cgaacacucc ggacucuggg      120

ucuccguccu cgccggccuc cuccuaggcg ccugccaagc ccaccccauc cccgacucau      180

ccccacuccu acaauucggc ggccaagucc gucaacgcua ccucuauacc gaugacgccc      240

aacaaaccga agcccaccuc gaaauccgcg aagacggaac cgucggcggc gccgcugacc      300

aaucacccga aucccuccuc caacucaaag cacucaaacc cggcguaauc caaauccucg      360

gcguaaaaac cucacgauuu cuaugucaaa gacccgacgg agcccuauac ggcucucuac      420

acuucgaccc agaagcaugc uccuuccgcg aacgacuccu cgaagacgga uacaacgucu      480

accaaucaga agcccacggc cuaccccucc accuccccgg caacaaaucu ccccaccgcg      540

accccgcacc ccgcggcccc gcccgcuucc ucccccuccc cggccuaccc ccagcccuac      600

ccgaaccacc cggcauacuc gcaccccaac cacccgacgu cggcuccucc gacccccuau      660

ccauggucgg cggcucccaa ggccgcuccc ccucauacga aucuuaagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5459
<211>  2340
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt8)

<400>  5459
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca cgaaacugcu cccaguauug cucuugcaac      120

acguccuacu ccaccuucua cugcuacacg ucgcuauacc cuaugccgaa ggacaaaaga      180

aacgucgcaa cacccuacac gaauuuaaga aaagcgccaa gaccacacuc acuaaagaag      240

auccccuacu caaaauaaag accaaaaagg ugaacucggc ugacgaaugc gccaaccgau      300

gcauccgaaa cagaggcuuc acuuuuaccu gcaaagccuu cguuuucgac aagagccgaa      360

aacgaugcua cugguaccca uucaacagca uguccuccgg gguaaagaaa ggcuucggac      420

augaguucga ucuauacgaa aauaaagacu acauaagaaa cugcauaauc ggcaaaggag      480

gguccuacaa aggcacaguc agcaucacaa agucagggau caaaugccaa cccuggaacu      540

ccaugauacc acacgagcac aguuuccucc cuaguagcua ccgaggaaaa gaccuccagg      600

agaacuacug ccgcaacccc cgcggggaag aaggcggacc uuggugcuuc acaagcaacc      660

ccgagguccg cuacgagguc ugcgacaucc cccaaugcag cgaagucgag ugcaugaccu      720

guaacggaga aucauaccga ggcccaaugg aucacaccga auccggaaaa acaugccaac      780

gaugggacca acaaacaccg caccgacaca aguuccuccc cgaacgguac cccgacaaag      840

gauucgacga caacuacugc cgcaaccccg acggaaaacc acgaccaugg ugcuacacgc      900

ucgacccgga cacccccugg gaauacugcg ccaucaaaac cugcgcacac ucagcgguga      960

acgaaaccga uguaccaaug gaaacaaccg aaugcaucca aggacaagga gagggcuaca     1020

ggggcacguc aaauaccauc uggaacggca uaccaugcca gcgcugggac agucaguacc     1080

cccacaaaca cgacauaacc cccgaaaacu ucaaaugcaa agaccucaga gaaaacuacu     1140

gccgcaaccc cgacggcgcc gaaucccccu gguguuucac aaccgaccca aacauccgcg     1200

ugggcuacug cucacaaauc cccaagugcg acguaucaag cggccaagac ugcuaucgcg     1260

ggaacggcaa aaacuacaug ggaaaccucu caaagaccag aagcggccua acaugcucaa     1320

ugugggacaa aaacauggag gaccuccacc ggcacaucuu uugggaaccc gacgcuucca     1380

aacucaacaa aaacuacugc cgaaaccccg acgacgaugc acacggccca uggugcuaca     1440

caggcaaccc ccugauaccc ugggacuacu gccccaucuc cagaugcgag ggcgacacaa     1500

caccgaccau cguaaaucuc gaccaccccg uaaucuccug cgccaaaaca aaacaacuaa     1560

gggucgugaa cggaaucccc acccaaacaa cagugggcug gauggucagc cucaaauaca     1620

gaaacaagca caucugcggc ggcucccuca ucaaggaaag cuggguacua acagccaggc     1680

aaugcuuccc cgccagaaau aaagaucuaa aagacuacga agccuggcua ggcauccaug     1740

acguccacga acgcggcgag gagaaacgaa aacaaauucu caacaucucu caacucgucu     1800

auggaccaga agggagcgac cucguucuuc ugaaacucgc ccggcccgca aucuuagaca     1860

acuucgucag cacaaucgac cuccccucau acggaugcac caucccagaa aagacaaccu     1920

gcagcauaua cggauggggc uacaccggcc ugaucaacgc agacggccuu cucagagucg     1980

cccaucucua caucauggga aacgaaaaau gcagccaaca ccaccaaggc aaaguaacgc     2040

ucaacgaauc cgaacucugc gccggagcag ggacuagugc aucacauuua aaagcaucuc     2100

agccuaccau gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc     2160

uuuuucguug guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu     2220

gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu     2340


<210>  5460
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt8)

<400>  5460
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaaagggg acccgaaaaa gccaagagga aagaugucga      120

gcuaugccuu uuucgugcaa acgugcaggg aagaacacaa gaaaaagcac ccggacgcga      180

gcgugaacuu uagcgaguuc ucgaaaaagu gcucagaaag guggaagacc augagcgcga      240

aagaaaaagg gaaauuugaa gauauggcaa aagcggacaa ggcaagguac gagcgagaaa      300

ugaagacaua uaucccgcca aagggcgaga caaagaagaa auucaaagac ccgaacgcgc      360

ccaagcgccc gccaucggcc uuuuuccuau ucugcagcga guacaggccc aagauaaagg      420

gcgagcaccc aggauugagc auaggcgaug ucgcgaaaaa gcuaggggaa auguggaaca      480

acacggccgc ggacgauaaa cagccguaug aaaagaaagc ggccaagcuc aaggaaaagu      540

acgagaaaga uaucgcggcc uauagagcga aaggaaaacc ggacgcggcc aagaaagggg      600

uagugaaagc ggaaaagagc aagaaaaaga aagaggaaga ggaagaugaa gaggacgagg      660

aagacgaaga ggaagaggaa gaugaagagg acgaggacga ggaagaggac gaugacgaug      720

aauagggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5461
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt8)

<400>  5461
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc ucuccugggu ccacuggacc cucgcccucc      120

uccucuaccu ucaccacgca aaaugguccc aagccgcccc caccaccgaa ggagaacaaa      180

aaucccacga agucauaaaa uucauggacg uauaccaacg aucauacugc cgacccaucg      240

aaacccuagu cgacaucuuc caagaauacc cagacgaaau cgaauacaua uucaaacccu      300

ccugcguacc ccucaugcgc ugcgccggcu gcugcaacga cgaagcccua gaaugcgucc      360

caacaucaga aucaaacauc accaugcaaa ucaugcgcau caaaccacac caaucccaac      420

acauaggcga aauguccuuc cuccaacacu cacgcugcga augccgcccc aaaaaagacc      480

gaaccaaacc cgaaaaaaaa ucaguccgag gcaaaggaaa aggccaaaaa cgcaagcgca      540

aaaaaucccg cuucaaaucc ugguccgucc acugcgaacc cugcuccgaa cgccgaaaac      600

accucuucgu ccaagaccca caaaccugca aaugcuccug caaaaacacc gacuccagau      660

gcaaagcacg ccaacucgaa cucaacgaaa gaaccugccg cugcgacaaa ccccgccgcu      720

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5462
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt9)

<400>  5462
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg aaaccggauu cgaacacuca ggccucuggg      120

ucucaguccu cgccggccuc cuccucggag ccugccaagc ccacccaauc cccgacuccu      180

caccacuccu ccaauucggc ggccaagucc gacaacgaua ccucuacacc gacgacgccc      240

aacaaaccga agcccaccuc gaaauccgcg aagacggcac aguaggaggc gccgccgacc      300

aaucacccga aucccuacuc caacuaaaag cacucaaacc cggcgucauc caaauacucg      360

gcgucaaaac cucaagauuc cucugccaac gccccgacgg cgcccucuac ggcucccucc      420

acuucgaccc cgaagccugc uccuuccgcg aacgccuccu cgaagacggc uacaacgucu      480

accaauccga agcccacggc cucccccucc accucccagg caacaaaucc ccacaccgcg      540

accccgcacc ccgcggccca gcccgcuucc ucccccuccc cggacuaccc ccugcccuac      600

ccgaaccacc aggcauccuc gcaccccaac cacccgacgu cggcuccucc gacccccucu      660

caaugguagg cggcucacaa ggccgauccc ccuccuacga auccuaagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5463
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt9)

<400>  5463
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca caaaacuccu uccgguacug cugcuacaac      120

acgugcuucu ccaccuccuu cuacuccacg ucgcaauccc cuaugcagaa gggcagaaaa      180

agcgacgcaa cacacuccac gaguucaaga aaucggccaa aacaacccua accaaagagg      240

acccccuccu caaaaucaaa accaagaaag uaaacuccgc cgacgagugc gccaacagau      300

gcauccgcaa ccggggcuuc accuucacau gcaaagccuu cguguucgau aaaagccgca      360

aacgaugcua cugguaccca uucaacucca ugagcucggg aguuaagaaa ggcuuuggcc      420

acgaauuuga ccuauacgag aauaaagacu acauaagaaa cugcaucauc gguaaaggcg      480

gcucauacaa agggaccgua uccaucacaa aaagcggaau aaaaugccaa ccguggaacu      540

cuaugauacc ccacgaacac ucauuccuac cauccucaua ccgcggcaaa gaccuacaag      600

agaacuacug ccgaaacccc cgaggagaag aagggggacc auggugcuuc accucaaacc      660

cagagguacg guacgaaguc ugcgacaucc cacaaugcag cgaaguagag ugcaugaccu      720

guaacggaga guccuaccgg ggaccaaugg accauaccga aucgggaaaa acuugccaac      780

gaugggauca acaaacaccc caucgucaca aauuccuacc ggaacgauac ccagacaaag      840

gauucgacga caacuacugc agaaaucccg acgguaaacc cagaccuugg ugcuacaccc      900

uagaccccga caccccaugg gaauacugcg ccauaaagac cugcgcacac ucugccguca      960

acgagaccga cguccccaug gaaacaaccg aaugcauaca ggggcaggga gagggcuacc     1020

gcggcaccag caacaccauc uggaacggua uacccugcca gcgaugggac agccaauacc     1080

cccacaagca cgacauaacc ccugagaacu ucaagugcaa agaccuacgc gaaaacuacu     1140

gccgaaaccc agacggcgcc gaaucaccau gguguuucac aacagaccca aacauccgcg     1200

ucggcuacug cucccaaaua cccaaaugcg acgucaguuc cggacaagac ugcuaccgag     1260

gcaacggaaa gaacuacaug ggaaaccucu ccaaaacccg uagcgguuua acaugcucca     1320

ugugggacaa gaacauggaa gaccuacaca gacauauauu cugggaaccc gacgcaagca     1380

aacucaacaa aaauuacugc cgcaaccccg acgacgaugc ccauggcccc uggugcuaca     1440

ccggcaaccc ccugaucccc ugggacuacu guccaauaag ccgaugcgag ggggacacca     1500

ccccuaccau cgucaaccug gaccaccccg ucaucuccug cgcaaaaacc aaacagcucc     1560

gaguagugaa cggcauccca acccagacaa cggucggaug gauggucuca cuaaaauacc     1620

gaaacaaaca cauaugcggu ggaucccuca ucaaagaaag cugggucuua accgcccgcc     1680

aaugcuuccc cgcacgaaac aaagaccuaa aagacuacga agcauggcua ggcauccacg     1740

acguacacga acgaggcgaa gaaaaacgaa agcaaauccu caacaucuca caguuagucu     1800

acggaccaga agguucagac cucgugcucc uaaaguuagc ccgccccgcc auacuagaca     1860

acuucgucag caccaucgac cuaccaucau acggaugcac cauaccagag aaaaccacau     1920

gcaguaucua cggcuggggc uacacgggcc ucaucaacgc cgacggccuc cuacgcguag     1980

cccaccucua uaucaugggc aacgaaaaau gcucacaaca ccaccaaggg aaaguaacac     2040

ugaacgaauc cgagcucugc gccggcgccg agaaaaucgg auccggcccc ugcgaaggag     2100

acuacggggg accacuaaua ugcgaacagc acaagaugcg aaugguccuc ggagucaucg     2160

uacccggccg aggcugcgca auacccaauc gccccggcau auucguucgc guagccuacu     2220

acgcuaaaug gauccacaaa gucauacuca ccuacaaacu auaaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5464
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt9)

<400>  5464
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaaagggg acccgaagaa accaagggga aaaaugucga      120

gcuaugccuu cuucgugcaa acgugcaggg aggaacacaa gaaaaagcac ccagacgcga      180

gcgugaacuu uagcgaguuc ucgaaaaagu gcucggaaag guggaagaca augagcgcga      240

aagagaaagg gaaauuugaa gauauggcga aagcggacaa ggccagguac gagcgagaga      300

ugaagaccua uaucccgccc aagggcgaga caaagaagaa auucaaagac ccgaacgcgc      360

caaagcgccc gcccucggca uuuuucuugu ucuguagcga guacaggcca aagaucaagg      420

gcgagcaccc aggcuugagc auaggcgaug ucgccaaaaa gcucggggaa auguggaaua      480

acacagcagc agacgauaaa cagcccuaug aaaagaaagc ggcaaagcuc aaggaaaagu      540

acgagaaaga uaucgcggcc uaucgcgcga aagggaaacc ggacgcggca aagaaagggg      600

ucgugaaagc ggaaaagagc aagaaaaaga aagaggaaga ggaagaugaa gaggacgagg      660

aagaugaaga ggaagaggaa gaugaagagg acgaggacga agaagaggac gaugacgaug      720

aauagggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5465
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt9)

<400>  5465
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc ucuccugggu ccacuggaca cucgcccucc      120

uccuauaccu acaccacgcc aaauggagcc aagccgcccc cacaaccgaa ggcgaacaaa      180

aaucccacga agucaucaaa uucauggacg ucuaccaacg cuccuacugc cgccccaucg      240

aaacccucgu cgacaucuuc caagaauacc ccgacgaaau cgaauacauc uucaaacccu      300

ccugcguccc ccucaugcgc ugcgccggcu gcugcaacga cgaagcccuc gaaugcgucc      360

ccaccucaga aucaaacaua acaaugcaaa ucaugcgcau caaaccccac caaucccaac      420

acaucggaga aauguccuuc cuccaacacu cacgcugcga augccgccca aaaaaagacc      480

gcaccaaacc cgaaaaaaaa uccguacgcg gcaaaggcaa aggccaaaaa cgcaaacgca      540

aaaaaucccg cuucaaauca uggucagucc acugcgaacc cugcagcgaa cgacgcaaac      600

accucuucgu ccaagaccca caaacaugca aaugcuccug caaaaacaca gacucgcgcu      660

gcaaagcccg ccaacucgaa cuaaacgaac gcaccugccg cugcgacaaa ccccgacgcu      720

agggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5466
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) 
       (opt11)

<400>  5466
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg aaaccggcuu cgaacacucc ggccucuggg      120

ucuccguccu cgccggccuc cuccuaggcg caugccaagc ccaccccaua cccgacuccu      180

caccccuccu ccaauucggc ggccaagucc gccaacgcua ccuauacacc gacgacgccc      240

aacaaacaga agcccaccuc gaaauccgag aagacggcac agucggcggc gccgccgacc      300

aaagccccga aucccuccuc caacucaaag cccucaaacc cggcgucauc caaauccucg      360

gcgucaaaac aucccgcuuc cuaugccaac gccccgacgg cgcccucuac ggcucacucc      420

acuucgaccc cgaagccugc uccuuccgcg aacgccuccu cgaagacggc uacaacgucu      480

accaauccga agcccacggc cuaccccuac accuccccgg caacaaaucc ccucaccgcg      540

accccgcacc ccgcggcccc gcccgcuucc uaccccuccc cggccucccc cccgcccuac      600

ccgaaccccc cggcauccuc gccccccaac ccccagacgu cggcuccucu gacccccucu      660

ccauggucgg cggcucccaa ggccgcucac ccuccuacga auccuaagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5467
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt11)

<400>  5467
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggaa caaaauuacu accaguccua cuacuccaac      120

acguccuacu ccaccuacua cuacuccacg ucgcaauccc cuacgccgaa ggacagaaaa      180

agcgaagaaa cacacuacac gaauuuaaga aaucagccaa aaccacccua accaaagaag      240

acccccuacu gaaaaucaaa acuaagaaag ucaacuccgc agaugagugc gcaaaccgau      300

gcauacgcaa ccgcggcuuc acauucacuu gcaaagccuu cguuuucgac aaaucacgaa      360

aacgcugcua cugguacccc uuuaacucga ugagcucagg cgugaagaaa ggcuucggcc      420

augaguucga ccuauacgaa aauaaagauu acauacguaa cugcaucauc ggaaaaggug      480

gcagcuacaa aggcacuguc ucaauaacga aaaguggcau caaaugccaa cccuggaacu      540

ccaugauccc ucacgaacac ucauuccucc ccuccagcua cagagggaaa gaccuacaag      600

aaaacuacug ccguaaucca agaggagaag aaggcggacc uuggugcuuc accuccaacc      660

ccgaaguaag auacgaagug ugcgacauac cacaaugcuc cgaagucgaa ugcaugaccu      720

gcaacggcga auccuaccga ggacccaugg accacaccga aucagguaag accugccaac      780

gcugggacca acaaacaccc cacagacaca aauuccuccc ugaacgcuac cccgacaaag      840

gcuucgacga caacuacugc aggaacccag acgguaaacc ccgacccugg uguuacaccc      900

ucgacccaga uacacccugg gaauacugcg ccauaaaaac augcgcacac uccgccguca      960

acgagacaga cguccccaug gaaaccaccg agugcauaca aggacaaggg gaaggauaca     1020

gaggaacauc aaacaccauu uggaacggca uacccugcca aagaugggac ucccaguauc     1080

cccacaaaca cgacaucaca ccagaaaacu ucaaaugcaa ggaccuacga gaaaacuacu     1140

gccgcaaccc agacggagcu gaaucccccu ggugcuucac aacagacccg aauauccgcg     1200

ucggauacug uucgcaaauc ccaaagugcg acgucagcuc aggacaagac ugcuacagag     1260

gaaacggcaa gaacuauaug ggcaaccuuu cgaaaacacg cagcggccua accugcucca     1320

ugugggacaa gaacauggaa gaccuccacc ggcacauauu cugggaaccc gacgcaagua     1380

aacuuaacaa aaacuacugu cgcaauccgg acgacgacgc ccacggcccu uggugcuaca     1440

ccgguaaccc ccuaaucccg ugggacuacu gccccauauc ccgaugcgaa ggagauacaa     1500

cacccaccau cgugaaccua gaccaccccg ucaucucaug cgcuaaaacg aaacagcucc     1560

gagucgucaa cggcauccca acgcaaacga ccgucggaug gauggucucc cugaaauacc     1620

gcaacaaaca cauaugcggc ggaagccuaa uaaaagaaag cuggguccuu acagcccggc     1680

aaugcuuccc agcccguaac aaagaccuca aagacuacga agccuggcuc ggcauccacg     1740

acguacauga acgaggggaa gaaaaacgca aacaaauacu caacaucucc cagcugguau     1800

acggcccgga aggaagcgac cucguccucu ugaaacuagc cagacccgcc auacuagaca     1860

acuucgucag caccaucgac cuccccucau acggcugcac caucccagaa aagacaaccu     1920

gcucaaucua cggcuggggc uacaccggac uaaucaacgc cgacggacuc cugcgggucg     1980

cccauuugua caucauggga aacgaaaaau gcucccaaca ccaccaaggc aaagucaccc     2040

ugaacgaauc cgaacucugc gcaggcgccg agaaaaucgg aucaggaccc ugcgaagggg     2100

acuacggggg cccccucauc ugcgagcaac auaaaaugcg uauggugcua ggcgugaucg     2160

uccccggacg cggaugcgcc aucccgaacc gccccgggau cuucguccgc gucgccuacu     2220

acgccaaaug gauacauaaa gucauucuca ccuacaagcu guaaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5468
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt11)

<400>  5468
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaaagggg acccgaaaaa gccgagggga aagaugucga      120

gcuaugccuu cuucgugcaa acgugcaggg aggaacacaa gaaaaagcac ccggacgcga      180

gcgugaacuu cagcgaguuc ucgaaaaagu gcucggaaag guggaagacc augagcgcga      240

aagagaaagg gaaauuugaa gauauggcga aagcggacaa ggcaagguac gagcgagaga      300

ugaagacaua uauaccacca aagggcgaga ccaagaaaaa guucaaggac ccgaacgcgc      360

ccaagcgccc gccaucggcc uuuuucuugu ucuguagcga guacaggccc aagaucaagg      420

gagagcaccc gggcuugagc auaggcgacg ucgcgaaaaa gcucggggaa auguggaaua      480

acacggccgc ggacgauaaa cagccauaug aaaagaaagc ggccaagcua aaggaaaagu      540

acgagaaaga uaucgcggca uaucgcgcga aagggaaacc ggacgcggcc aagaaaggag      600

ucguaaaagc ggaaaagagc aagaaaaaga aagaggaaga ggaagaugaa gaggacgagg      660

aagaugaaga ggaagaggaa gaugaagagg acgaggacga ggaagaggac gaugacgaug      720

aauagggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5469
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt11)

<400>  5469
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc uauccugggu ccacuggaca cucgcccucc      120

uccucuaccu ccaccacgcc aaaugguccc aagcagcacc caccacagaa ggcgaacaaa      180

aaucccacga agucaucaag uucauggacg ucuaccaacg cucauacugc cgccccaucg      240

aaacacucgu agacaucuuc caagaauacc ccgacgaaau cgaauacauc uucaaacccu      300

ccugcguccc acuaaugcgc ugcgccggau gcugcaacga cgaagcccuc gaaugcgucc      360

caaccuccga auccaacauc accaugcaaa ucaugcgcau caaaccccac caaucccaac      420

acaucggcga aauguccuuc cuccaacacu cccgcugcga augccgcccc aaaaaagacc      480

gcaccaaacc cgaaaaaaaa ucaguccgcg gcaaaggcaa aggucaaaaa cgaaaacgca      540

aaaaaucacg cuucaaaucc ugguccgucc acugcgaacc cugcucagaa cgacgcaaac      600

accucuucgu ccaagacccc caaaccugca aaugcucaug caaaaacacc gacucccgau      660

gcaaagcccg ccaacucgaa cucaacgaac gaaccugccg cugcgacaaa ccccgacgcu      720

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5470
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) 
       (opt12)

<400>  5470
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucugacg aaacagguuu cgaacacuca ggacuauggg      120

ucucaguauu agcaggacua uuauuaggag caugucaagc acauccaaua ccagacucau      180

caccacuacu acaauucggc ggacaaguaa gacaaagaua cuuauacaca gacgaugcac      240

aacaaacaga agcacauuua gaaauaagag aagauggcac aguaggcgga gcagcagacc      300

aaucaccaga aucacuauua caauuaaaag cauuaaaacc aggaguaaua caaauauuag      360

gaguaaaaac aucaagauuc uuaugucaaa gaccugacgg agcacuauac ggaucacuac      420

acuuugaccc agaagcaugc ucauuuagag aaagauuauu agaagacgga uacaauguau      480

aucaaucaga agcacacgga uuaccauuac acuuacccgg aaauaaauca ccacauagag      540

acccagcacc aagaggaccu gcaagauuuc uaccucuacc aggacuacca ccagcacuac      600

cugaaccacc aggaauauua gcaccacaac caccagacgu aggauccuca gaccccuuau      660

caaugguagg cggaucacaa ggaagaucac caucauauga aucauaagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5471
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt12)

<400>  5471
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggaa cuaaauuacu accaguucua uuacuucaac      120

acguccuauu acauuuauua cuauuacacg uugcaauacc auaugcagaa ggacaaaaaa      180

aaagaaggaa caccuuacac gaauuuaaaa aaucggcaaa aacaacccuc acaaaggaag      240

acccacuauu aaaaaucaaa acaaaaaaag ugaauagugc agacgaaugu gcaaauagau      300

gcauaagaaa cagaggauuu acauucacuu guaaagcauu uguauuugau aaaucaagga      360

aaagguguua uugguauccu uuuaacucaa ugucuagugg aguaaaaaaa ggauucggac      420

augaauuuga ccuauaugaa aauaaagacu auauaagaaa uugcauaaua ggaaaaggug      480

gaucauauaa agggacaguu agcauaacca aaucaggcau aaaaugucaa ccauggaauu      540

caaugauacc acaugaacau uccuuucuac cuaguaguua ucguggaaaa gauuuacaag      600

aaaauuauug uagaaaccca agaggagaag aaggagggcc auggugcuuu acaagcaacc      660

cagaagucag auaugaagua ugugacauac cacaauguuc agaaguagaa uguaugacau      720

gcaauggaga aucguauaga gguccaaugg accauacaga aucaggaaaa acaugucaaa      780

gaugggauca acaaacccca caucgacaua aauucuuacc agaacgauau ccagacaaag      840

gguucgacga uaauuauugc agaaauccag augggaaacc aagacccugg uguuacacuc      900

uagaccccga uacaccaugg gaauauugug caauaaaaac augcgcacac ucagcaguaa      960

augagacuga ugucccaaug gaaacuacag aaugcauuca aggacaaggu gaagguuacc     1020

gaggcacaag uaauacuaua uggaauggga uaccauguca aagaugggac agucaauacc     1080

cacauaaaca ugauauaacg ccagaaaauu uuaaauguaa agauuuaaga gaaaauuauu     1140

gcagaaaucc ugauggcgcg gaaaguccau ggugcuucac aacugauccu aacauaagag     1200

uugguuauug cagucaaaua ccuaaaugcg auguaucauc cggacaagau uguuauaggg     1260

guaauggaaa aaauuauaug ggcaauuuau caaaaacacg uaguggauua acauguucaa     1320

ugugggauaa aaauauggaa gauuuacauc gacacauuuu cugggaaccc gaugcuagua     1380

aauuaaacaa aaacuauugu cgaaacccag augaugaugc acauggacca uggugcuaua     1440

cagguaaccc acuuauacca ugggacuauu guccuauauc aagaugugaa ggcgauacaa     1500

caccuacuau agucaauuua gaucauccug uaaucaguug cgcuaaaaca aaacaauuaa     1560

gaguuguaaa cggaauucca acacaaacaa caguaggaug gaugguauca cucaaauacc     1620

gaaauaaaca cauaugcgga gguucuuuaa uaaaagaaag cuggguauua accgcaagac     1680

aaugcuuccc ggcaagaaau aaagauuuaa aagauuauga agcaugguua ggaauacacg     1740

auguacacga aaggggagaa gaaaaaagaa aacaaauacu aaauauauca caauuaguau     1800

acggcccaga agggagcgau cuaguucuuc uaaaauuagc cagaccagca auauuagaua     1860

auuuuguauc uacuaucgau cuaccaucau auggauguac aauaccugag aaaacaacau     1920

guucaauaua uggaugggga uauacuggau uaauaaacgc cgauggacuu cuuagaguag     1980

cacacuuaua uauaauggga aacgaaaaau gcucacaaca ucaucaagga aaaguuacac     2040

uaaacgaauc agaacuaugu gcuggcgcag aaaaaaucgg aucaggccca ugcgaaggug     2100

auuacggcgg accacuuaua ugugaacaac auaaaaugcg caugguauua ggagucauag     2160

uucccggucg gggcugugcg auaccaaaca gaccaggcau auuuguccgu guagccuacu     2220

augcaaaaug gauacauaaa guaauauuaa cauauaaauu auaaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5472
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt12)

<400>  5472
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaggag acccaaaaaa accaagagga aaaaugucaa      120

gcuacgcauu cuucguacaa acaugcagag aagaacacaa aaaaaaacac ccagacgcaa      180

gcguaaacuu cagcgaauuc agcaaaaaau gcucagaaag guggaaaaca augagcgcaa      240

aagagaaagg aaaauucgaa gacauggcaa aagcagacaa agcaagauac gaaagagaaa      300

ugaaaacaua cauaccacca aaaggagaaa caaaaaaaaa auuuaaagac ccaaacgcac      360

caaaaagacc accaucagca uucuuccuau ucugcaguga auacagacca aaaauaaaag      420

gagaacaccc aggacuaagc auaggagacg uagcaaaaaa auuaggagaa auguggaaca      480

acacagcagc agacgacaaa caaccauacg aaaaaaaagc agcaaaauua aaagaaaaau      540

acgaaaagga cauagcagca uaucgagcaa aaggaaaacc agacgcagca aaaaaaggag      600

uaguaaaagc agaaaaaagc aaaaaaaaaa aagaagaaga agaagacgaa gaagacgaag      660

aagacgaaga agaagaagaa gacgaagaag acgaagacga agaagaagac gacgacgacg      720

aauaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5473
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt12)

<400>  5473
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuac uaucaugggu acacuggaca cuagcauuac      120

uacuauacuu acaccacgca aaauggucac aagcagcacc aacaacagaa ggagaacaaa      180

aaucacacga aguaauaaaa uucauggacg uauaccaacg aucauacugc agaccaauag      240

aaacacuagu agacauauuc caagaauacc cagacgaaau agaauacaua uucaaaccau      300

caugcguacc auuaaugaga ugcgcaggau gcugcaacga cgaagcauua gaaugcguac      360

caacaucaga aucaaacaua acaaugcaaa uaaugagaau aaaaccacac caaucacaac      420

acauaggaga aaugucauuc cuacaacauu caagaugcga augcagacca aaaaaagaca      480

gaacaaaacc agaaaaaaaa ucaguaagag gaaaaggaaa aggacaaaaa agaaaaagaa      540

aaaaaucaag auucaaauca uggucaguac acugcgaacc augcucagaa cgaagaaaac      600

acuuauuugu acaagaccca caaacaugca aaugcucaug caaaaacaca gacucaagau      660

gcaaagcaag acaacuagaa cuaaaugaaa gaacaugcag augugacaaa ccaagacgau      720

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5474
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) 
       (opt13)

<400>  5474
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucagacg aaacaggauu ugaacacuca ggacuauggg      120

uaucaguacu agcaggauua uuacuaggag ccugccaagc acacccaaua ccagacucau      180

caccauuauu acaauucgga ggacaaguua gacaaagaua ucuauauaca gaugacgcac      240

aacaaacaga agcacacuua gaaauaagag aagacggaac aguaggagga gcagcagacc      300

aaucaccaga aucccuacua caauuaaaag cacuaaaacc aggaguaaua caaauauuag      360

gaguaaaaac aucaagauuc cuaugccaaa gaccagacgg agcacuauac ggcucacuac      420

acuuugaccc agaagcaugc ucauucagag aaagacuacu agaagacgga uauaauguau      480

aucaaucaga agcacacgga cuaccuuuac auuuaccagg aaacaaauca ccacacagag      540

acccagcacc aagaggccca gcacgcuuuu uaccauuacc aggacuacca ccagcauuac      600

cagaaccacc aggaauacua gcaccacaac caccagaugu uggaagcuca gacccacuau      660

caaugguagg aggaucacaa ggaagaucac caucauauga aucauaagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5475
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt13)

<400>  5475
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggaa caaaacuuuu accuguucua uuauuacaac      120

acguccuguu acacuuauua uuacuacaug uagccauacc uuacgcagaa ggacaaaaga      180

aacgaagaaa cacacuucau gaauuuaaga aauccgcaaa aacaacauua acaaaagaag      240

auccauuauu aaaaauaaaa acaaagaaag uuaauucagc agaugaaugu gcaaauagau      300

guauaagaaa cagaggauuu accuuuacau guaaagcauu uguauucgac aaaucaagga      360

aacgauguua cugguaucca uucaauagua ugaguucugg aguaaagaaa ggauucgguc      420

augaguucga ccuauaugaa aauaaagacu auauuagaaa uuguauaauc ggcaaaggug      480

ggucuuauaa aggcacuguu aguauaacaa aaucaggaau aaaaugucaa ccauggaaua      540

gcaugauacc acacgaacac ucauuucucc caucuucaua caggggcaaa gaccuacaag      600

aaaauuauug uagaaaccca aggggagaag aaggaggccc augguguuuu acaucgaauc      660

cugaaguacg auaugaagua ugugacaucc cccaaugcag ugaaguagaa uguaugacuu      720

guaaugguga aucauaccga ggaccuaugg accauacaga aucaggaaaa acuugccaac      780

gaugggauca acaaaccccu caucgacaca aauuuuuacc agaacguuac ccagauaaag      840

gauuugacga uaauuacugu agaaauccag acgguaaacc ucgacccugg uguuacacuc      900

uugauccaga uacaccaugg gaauauugcg caauaaaaac uugcgcacau ucugcaguaa      960

augaaacaga cguuccaaug gaaacuaccg aauguauaca aggccaagga gaaggcuaua     1020

gagguacauc aaauacaaua uggaauggca uacccugcca aaggugggac ucucaauauc     1080

cacauaaaca ugauauaaca ccagaaaacu uuaaauguaa agauuuaaga gaaaauuacu     1140

guagaaaucc ggauggagca gaaucucccu gguguuucac uaccgauccu aacauaagag     1200

uaggauauug uagccaaaua ccuaaaugug auguuagcuc aggucaagac ugcuacagag     1260

guaauggcaa aaauuacaug gggaaucuca guaaaacacg uaguggacuc acauguucaa     1320

ugugggauaa aaauauggaa gaccugcaca gacauauauu cugggaaccu gaugcuucaa     1380

aauuaaauaa aaauuauugc agaaauccag augaugacgc ucacggacca ugguguuaca     1440

cugguaaucc auuaauacca ugggauuauu guccaauauc aagaugcgaa ggugauacaa     1500

cuccaacaau aguaaaucua gaucauccag uaauauccug ugcaaaaaca aaacaacuaa     1560

gaguaguaaa cggaauacca acacaaacaa caguaggaug gaugguuagu uuaaaauaca     1620

gaaauaaaca uauaugugga ggauccuuaa uaaaagaauc auggguauua acugcaagac     1680

aauguuuccc agcaaggaac aaagauuuaa aagauuacga agcauggcua ggaauacaug     1740

auguucacga aagaggagaa gaaaaacgua aacaaauuuu gaacauuuca caacuuguau     1800

acggcccaga aggaucugau uuaguauuau uaaaguuagc aagaccagca auucucgaua     1860

auuucguauc aacgauagau cuccccaguu acggcuguac gauaccagaa aagacaacau     1920

gcaguauaua cggaugggga uauacaggac uaaucaacgc agauggacuu uuaagaguag     1980

cccacuuaua uauaaugggu aacgaaaaau guucacaaca ucaucaagga aaaguaacac     2040

uaaaugaaag cgaauuaugu gcaggcgcag agaaaauagg aagcggaccu ugugaaggcg     2100

auuacggugg accacuaaua ugugaacaac auaaaaugag aaugguauua ggaguaauag     2160

uuccaggacg uggaugugcc auaccaaacc gaccaggaau auuuguuagg guagccuacu     2220

acgcaaaaug gauucacaaa guaauauuaa cauauaaacu auaaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5476
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt13)

<400>  5476
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaggag acccaaaaaa accgagagga aaaaugagca      120

gcuacgcauu uuucguacaa acaugcagag aagaacacaa aaaaaaacac ccagacgcaa      180

gcguaaacuu uagcgaauuu ucaaaaaaau gcucagaaag auggaaaaca augagcgcaa      240

aagaaaaagg aaaauucgaa gacauggcga aagcagacaa agcaagauau gaaagagaaa      300

ugaaaacaua cauaccacca aaaggagaaa ccaaaaaaaa auuuaaagac ccaaacgcac      360

caaaaagacc accaagcgca uucuuucuau ucugcaguga auacagacca aaaauaaaag      420

gagaacaccc aggauuaagc auaggagacg uagcaaaaaa acuaggagaa auguggaaca      480

acacagcagc agacgacaaa caaccauacg aaaaaaaagc agcaaaacua aaagaaaaau      540

acgaaaaaga cauagcagca uauagagcaa aaggaaaacc agacgcagca aaaaaaggag      600

uaguaaaagc agaaaaaagc aaaaaaaaaa aagaagaaga agaagacgaa gaagacgaag      660

aagacgaaga agaagaagaa gacgaagaag acgaagacga agaagaagac gacgacgacg      720

aauaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5477
<211>  992
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt13)

<400>  5477
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuac uaucaugggu acacuggaca cuagcacuac      120

uacuauacuu acaccacgca aaauggaguc aagcagcacc aacaacagaa ggagaacaaa      180

aaagccacga aguaauaaaa uucauggacg uauaucaacg aucauacugc agaccaauag      240

aaacacuagu agauaucuuc caagaauacc cagacgaaau agaauacaua uucaaaccau      300

caugcguacc auuaaugaga ugcgcaggau gcugcaacga cgaagcacua gaaugcguac      360

caacaucaga aucaaacaua acaaugcaaa uaaugagaau aaaaccccac caaagccaac      420

acauaggaga aaugucauuc cuacaacacu caagaugcga augcagaccc aaaaaagacc      480

gaacaaaacc agaaaaaaaa ucaguaagag gaaaaggaaa aggacaaaaa agaaaacgaa      540

aaaaaucacg auucaaauca uggucaguac acugcgaacc augcucugaa agaagaaaac      600

accuauucgu acaagaccca caaacaugua aaugcagcug caaaaacaca gacucaagau      660

gcaaagcaag acaacuagaa uuaaacgaaa gaacaugcag augcgacaaa ccacgaagau      720

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      780

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      840

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      900

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    992


<210>  5478
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (wt)

<400>  5478
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucggacg agaccggguu cgagcacuca ggacuguggg      120

uuucugugcu ggcuggucuu cugcugggag ccugccaggc acaccccauc ccugacucca      180

guccucuccu gcaauucggg ggccaagucc ggcagcggua ccucuacaca gaugaugccc      240

agcagacaga agcccaccug gagaucaggg aggaugggac gguggggggc gcugcugacc      300

agagccccga aagucuccug cagcugaaag ccuugaagcc gggaguuauu caaaucuugg      360

gagucaagac auccagguuc cugugccagc ggccagaugg ggcccuguau ggaucgcucc      420

acuuugaccc ugaggccugc agcuuccggg agcggcuucu ugaggacgga uacaauguuu      480

accaguccga agcccacggc cucccgcugc accugccagg gaacaagucc ccacaccggg      540

acccugcacc ccgaggacca gcucgcuucc ugccacuacc aggccugccc cccgcacucc      600

cggagccacc cggaauccug gccccccagc cccccgaugu gggcuccucg gacccucuga      660

gcaugguggg agguucccag ggccgaagcc ccagcuacga guccugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5479
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (wt) 
       R5988/R6155/R6227

<400>  5479
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucggacg agaccggguu cgagcacuca ggacuguggg      120

uuucugugcu ggcuggucuu cugcugggag ccugccaggc acaccccauc ccugacucca      180

guccucuccu gcaauucggg ggccaagucc ggcagcggua ccucuacaca gaugaugccc      240

agcagacaga agcccaccug gagaucaggg aggaugggac gguggggggc gcugcugacc      300

agagccccga aagucuccug cagcugaaag ccuugaagcc gggaguuauu caaaucuugg      360

gagucaagac auccagguuc cugugccagc ggccagaugg ggcccuguau ggaucgcucc      420

acuuugaccc ugaggccugc agcuuccggg agcggcuucu ugaggacgga uacaauguuu      480

accaguccga agcccacggc cucccgcugc accucccagg gaacaagucc ccacaccggg      540

acccugcacc ccgaggacca gcucgcuucc ugccacuacc aggccugccc cccgcacucc      600

cggagccacc cggaauccug gccccccagc cccccgaugu gggcuccucg gacccucuga      660

gcaugguggg agguucccag ggccgaagcc ccagcuacga guccugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5480
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (wt)

<400>  5480
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggga ccaaacuucu gccgguccug uugcugcagc      120

auguccuccu gcaccuccuc cugcuucaug ucgccauccc cuaugcagaa ggacagaaga      180

aaagaagaaa uacacuucau gaauuuaaaa agucagcaaa aacuacucuu accaaggaag      240

acccauuacu gaagauuaaa accaaaaaag ugaacucugc agaugagugu gccaacaggu      300

guaucaggaa caggggcuuu acguucacuu gcaaggccuu cguuuuugau aagucaagaa      360

aacgaugcua cugguauccu uucaauagua ugucaagugg agugaaaaaa ggguuuggcc      420

augaauuuga ccucuaugaa aacaaagacu auauuagaaa cugcaucauu gguaaaggag      480

gcagcuauaa agggacggua uccaucacua agaguggcau caaaugccag ccuuggaauu      540

ccaugauccc ccaugaacac agcuuuuugc cuucgagcua ucgcgguaaa gaccuacagg      600

aaaacuacug ucgaaauccu cgaggggaag aagggggacc cugguguuuc acaagcaauc      660

cagagguacg cuacgaaguc ugugacauuc cucaguguuc agaaguugaa ugcaugaccu      720

gcaaugguga aagcuacaga ggucccaugg aucacacaga aucaggcaag acuugucagc      780

gcugggacca gcagacacca caccggcaca aguucuugcc agaaagauau cccgacaagg      840

gcuuugauga uaauuauugc cgcaauccug auggcaagcc gaggccaugg ugcuacacuc      900

uugacccuga caccccuugg gaguauugug caauuaaaac gugcgcucac agugcuguga      960

augagacuga ugucccuaug gaaacaacug aaugcauuca aggccaagga gaagguuaca     1020

ggggaaccag caauaccauu uggaauggaa uucccuguca gcguugggau ucgcaguacc     1080

cucacaagca ugauaucacu cccgagaacu ucaaaugcaa ggaccuuaga gaaaauuauu     1140

gccgcaaucc agauggggcu gaaucaccau gguguuuuac cacugaccca aacauccgag     1200

uuggcuacug cucucaaauu cccaagugug acgugucaag uggacaagau uguuaucgug     1260

gcaaugggaa aaauuacaug ggcaacuuau ccaaaacaag gucuggacuu acauguucca     1320

ugugggacaa gaauauggag gauuuacacc gucauaucuu cugggagcca gaugcuagca     1380

aauugaauaa gaauuacugc cggaauccug augaugaugc ccauggaccu uggugcuaca     1440

cggggaaucc ucuuauuccu ugggauuauu gcccuauuuc ccguugugaa ggagauacua     1500

caccuacaau ugucaauuug gaccauccug uaauauccug ugccaaaaca aaacaacugc     1560

ggguuguaaa uggcauucca acacaaacaa caguagggug gaugguuagu uugaaauaca     1620

gaaauaaaca uaucugugga ggaucauuga uaaaggaaag uuggguucuu acugcaagac     1680

aauguuuucc agccagaaac aaagacuuga aagacuauga agcuuggcuu ggcauccacg     1740

auguucauga gagaggcgag gagaagcgca agcagaucuu aaacauuucc cagcuggucu     1800

augguccuga aggcucagac uugguuuuac ugaagcuugc ucgaccugca auccuggaua     1860

acuuugucag uacaauugau uuaccuaguu augguuguac aaucccugaa aagaccacuu     1920

gcaguauuua cggcuggggc uacacuggau ugaucaacgc ggaugguuua uuacgaguag     1980

cucaucugua uauuaugggg aaugagaaau gcagucagca ccaucaaggc aaggugacuu     2040

ugaaugaguc ugaguuaugu gcuggggcug aaaagauugg aucaggacca ugugagggag     2100

auuauggugg cccacucauu ugugaacaac acaaaaugag aaugguucuu ggugucauug     2160

uuccuggucg uggaugugcc aucccaaauc guccugguau uuuuguucga guagcauauu     2220

augcaaaaug gauacacaaa guaauuuuga cauacaaguu guaaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5481
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (wt)

<400>  5481
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggga ccaaacuucu gccgguccug uugcugcagc      120

auguccuccu gcaccuccuc cugcuucaug ucgccauccc cuaugcagaa ggacagaaga      180

aaagaagaaa uacacuucau gaauuuaaaa agucagcaaa aacuacucuu accaaggaag      240

acccauuacu gaagauuaaa accaaaaaag ugaacucugc agaugagugu gccaacaggu      300

guaucaggaa caggggcuuu acguucacuu gcaaggccuu cguuuuugau aagucaagaa      360

aacgaugcua cugguauccu uucaauagua ugucaagugg agugaaaaaa ggguuuggcc      420

augaauuuga ccucuaugaa aacaaagacu auauuagaaa cugcaucauu gguaaaggag      480

gcagcuauaa agggacggua uccaucacua agaguggcau caaaugccag ccuuggaacu      540

ccaugauccc ccaugaacac agcuuuuugc cuucgagcua ucgcgguaaa gaccuacagg      600

aaaacuacug ucgaaauccu cgaggggaag aagggggacc cugguguuuc acaagcaauc      660

cagagguacg cuacgaaguc ugugacauuc cucaguguuc agaaguugaa ugcaugaccu      720

gcaaugguga aagcuacaga ggucccaugg aucacacaga aucaggcaag acuugucagc      780

gcugggacca gcagacacca caccggcaca aguucuugcc agaaagauau cccgacaagg      840

gcuuugauga uaauuauugc cgcaauccug auggcaagcc gaggccaugg ugcuacacuc      900

uugacccuga caccccuugg gaguauugug caauuaaaac gugcgcucac agugcuguga      960

augagacuga ugucccuaug gaaacaacug aaugcauuca aggccaagga gaagguuaca     1020

ggggaaccag caauaccauu uggaauggaa uccccuguca gcguugggau ucgcaguacc     1080

cucacaagca ugauaucacu cccgagaacu ucaaaugcaa ggaccuuaga gaaaauuauu     1140

gccgcaaucc agauggggcu gaaucaccau gguguuuuac cacugaccca aacauccgag     1200

uuggcuacug cucucaaauu cccaagugug acgugucaag uggacaagau uguuaucgug     1260

gcaaugggaa aaauuacaug ggcaacuuau ccaaaacaag gucuggacuu acauguucca     1320

ugugggacaa gaauauggag gauuuacacc gucauaucuu cugggagcca gaugcuagca     1380

aauugaauaa gaauuacugc cggaauccug augaugaugc ccauggaccu uggugcuaca     1440

cggggaaucc ucuuauuccu ugggauuauu gcccuauuuc ccguugugaa ggagauacua     1500

caccuacaau ugucaauuug gaccauccug uaauauccug ugccaaaaca aaacaacugc     1560

ggguuguaaa uggcauucca acacaaacaa caguagggug gaugguuagu uugaaauaca     1620

gaaauaaaca uaucugugga ggaucauuga uaaaggaaag uuggguucuu acugcaagac     1680

aauguuuucc agccagaaac aaagacuuga aagacuauga agcauggcuu ggcauccacg     1740

auguucauga gagaggcgag gagaagcgca agcagaucuu aaacauuucc cagcuggucu     1800

augguccuga aggcucagac uugguuuuac ugaagcuggc ucgaccugca auccuggaua     1860

acuuugucag uacaauugau uuaccuaguu augguuguac aaucccugaa aagaccacuu     1920

gcaguauuua cggcuggggc uacacuggau ugaucaacgc ggaugguuua uuacgaguag     1980

cucaucugua uauuaugggg aaugagaaau gcagucagca ccaucaaggc aaggugacuu     2040

ugaaugaguc ugaguuaugu gcuggggcug aaaagauugg aucaggacca ugugagggag     2100

auuauggugg cccacucauu ugugaacaac acaaaaugag aaugguucuu ggugucauug     2160

uuccuggucg uggaugugcc aucccaaauc guccugguau uuuuguucga guagcauauu     2220

augcaaaaug gauacacaaa guaauuuuga cauacaaguu guaaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5482
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (wt)

<400>  5482
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaaggag auccuaagaa gccgagaggc aaaaugucau      120

cauaugcauu uuuugugcaa acuugucggg aggagcauaa gaagaagcac ccagaugcuu      180

cagucaacuu cucagaguuu ucuaagaagu gcucagagag guggaagacc augucugcua      240

aagagaaagg aaaauuugaa gauauggcaa aagcggacaa ggcccguuau gaaagagaaa      300

ugaaaaccua uaucccuccc aaaggggaga caaaaaagaa guucaaggau cccaaugcac      360

ccaagaggcc uccuucggcc uucuuccucu ucugcucuga guaucgccca aaaaucaaag      420

gagaacaucc uggccugucc auuggugaug uugcgaagaa acugggagag auguggaaua      480

acacugcugc agaugacaag cagccuuaug aaaagaaggc ugcgaagcug aaggaaaaau      540

acgaaaagga uauugcugca uaucgagcua aaggaaagcc ugaugcagca aaaaagggag      600

uugucaaggc ugaaaaaagc aagaaaaaga aggaagagga ggaagaugag gaagaugaag      660

aggaugagga ggaggaggaa gaugaagaag augaagauga agaagaagau gaugaugaug      720

aauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5483
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (wt)

<400>  5483
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuucugc ucucuugggu gcacuggacc cuggcuuuac      120

ugcuguaccu ccaccaugcc aagugguccc aggcugcacc cacgacagaa ggagagcaga      180

agucccauga agugaucaag uucauggaug ucuaccagcg aagcuacugc cguccgauug      240

agacccuggu ggacaucuuc caggaguacc ccgacgagau agaguacauc uucaagccgu      300

ccugugugcc gcugaugcgc ugugcaggcu gcuguaacga ugaagcccug gagugcgugc      360

ccacgucaga gagcaacauc accaugcaga ucaugcggau caaaccucac caaagccagc      420

acauaggaga gaugagcuuc cuacagcaca gcagauguga augcagacca aagaaagaca      480

gaacaaagcc agaaaaaaaa ucaguucgag gaaagggaaa gggucaaaaa cgaaagcgca      540

agaaaucccg guuuaaaucc uggagcguuc acugugagcc uuguucagag cggagaaagc      600

auuuguuugu ccaagauccg cagacgugua aauguuccug caaaaacaca gacucgcguu      660

gcaaggcgag gcagcuugag uuaaacgaac guacuugcag augugacaag ccaaggcggu      720

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5484
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt1)

<400>  5484
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgacg agaccggcuu cgagcacucc gggcuguggg      120

ugagcguccu cgccggccug cugcucgggg ccugccaggc ccaccccauc ccggacucca      180

gcccccugcu gcaguucggc ggccaggugc gccagcggua ccucuacacc gacgacgccc      240

agcagacgga ggcccaccug gagauccgcg aggacgggac cgugggcggg gccgccgacc      300

agucccccga gagccugcuc cagcugaagg cgcugaagcc cggcgucauc cagauccucg      360

gggugaagac cucccgguuc cugugccagc gcccggacgg cgcccuguac gggagccucc      420

acuucgaccc cgaggccugc uccuuccggg agcgccugcu cgaggacggc uacaacgugu      480

accagagcga ggcccacggc cugccccugc accuccccgg gaacaagucc ccgcaccgcg      540

accccgcgcc ccggggcccc gcccgcuucc ugccgcugcc cgggcucccg cccgcccugc      600

ccgagccgcc cggcauccug gcgccccagc cgcccgacgu cggcagcucc gacccccuca      660

gcaugguggg gggcucccag ggccggagcc ccuccuacga gagcugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5485
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt1) R6151/R6224

<400>  5485
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca ccaagcugcu ccccgugcug cugcuccagc      120

acguccugcu gcaccuccug cugcuccacg uggccauccc guacgccgag gggcagaaga      180

agcgccggaa cacccugcac gaguucaaga agagcgcgaa gacgacccug accaaggagg      240

acccccuccu gaagaucaag accaagaagg ugaacuccgc cgacgagugc gccaaccgcu      300

gcauccggaa ccgcggcuuc acguucaccu gcaaggccuu cgucuucgac aagagccgga      360

agcgcugcua cugguacccc uucaacucca ugagcuccgg ggugaagaag ggcuucgggc      420

acgaguucga ccuguacgag aacaaggacu acauccggaa cugcaucauc ggcaagggcg      480

ggagcuacaa gggcaccgug uccaucacca agagcgggau caagugccag cccuggaacu      540

ccaugauccc gcacgagcac agcuuccucc ccuccagcua ccgcggcaag gaccugcagg      600

agaacuacug ccggaacccc cgcggggagg agggcggccc cuggugcuuc acguccaacc      660

cggagguccg guacgaggug ugcgacaucc cccagugcag cgagguggag ugcaugaccu      720

gcaacgggga guccuaccgc ggccccaugg accacaccga gagcgggaag accugccagc      780

ggugggacca gcagacgccc caccgccaca aguuccugcc ggagcgguac cccgacaagg      840

gcuucgacga caacuacugc cgcaaccccg acggcaagcc ccggccgugg ugcuacaccc      900

ucgaccccga cacccccugg gaguacugcg ccaucaagac cugcgcgcac uccgccguca      960

acgagacgga cgugcccaug gagaccaccg agugcaucca ggggcagggc gagggguacc     1020

gcggcaccag caacacgauc uggaacggga ucccgugcca gcggugggac ucccaguacc     1080

cccacaagca cgacaucacc cccgagaacu ucaagugcaa ggaccugcgc gagaacuacu     1140

gccggaaccc cgacggcgcc gagagcccgu ggugcuucac caccgacccc aacauccgcg     1200

ugggcuacug cagccagauc cccaagugcg acgucuccag cgggcaggac ugcuaccgcg     1260

gcaacgggaa gaacuacaug ggcaaccugu ccaagacgcg gagcgggcuc accugcucca     1320

ugugggacaa gaacauggag gaccugcacc gccacaucuu cugggagccc gacgccagca     1380

agcugaacaa gaacuacugc cggaacccgg acgacgacgc gcacggcccc uggugcuaca     1440

ccggcaaccc ccucaucccg ugggacuacu gccccaucuc ccgcugcgag ggggacacca     1500

cgcccaccau cgugaaccug gaccaccccg ugaucagcug cgccaagacc aagcagcugc     1560

gggucgugaa cggcaucccg acccagacga ccguggggug gauggucucc cucaaguacc     1620

gcaacaagca caucugcggc gggagccuga ucaaggaguc cugggugcug accgcccggc     1680

agugcuuccc cgcccgcaac aaggaccuca aggacuacga ggccuggcug ggcauccacg     1740

acgugcacga gcggggcgag gagaagcgca agcagauccu gaacaucagc cagcucgucu     1800

acgggcccga gggcuccgac cuggugcugc ucaagcuggc gcggcccgcc auccuggaca     1860

acuucgugag caccaucgac cucccguccu acgggugcac gauccccgag aagaccaccu     1920

gcagcaucua cggcuggggc uacaccgggc ugaucaacgc cgacggccug cuccgcgucg     1980

cccaccugua caucaugggg aacgagaagu gcucccagca ccaccagggc aaggugaccc     2040

ugaacgagag cgagcucugc gccggggcgg agaagaucgg cuccggcccc ugcgaggggg     2100

acuacggcgg gccccugauc ugcgagcagc acaagaugcg gaugguccug ggcgugaucg     2160

ugccggggcg cggcugcgcc auccccaacc ggcccggcau cuucguccgc guggccuacu     2220

acgccaagug gauccacaag gugauccuga cguacaagcu cugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5486
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt1)

<400>  5486
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaggggg accccaagaa gccgcgcggc aagaugagca      120

gcuacgccuu cuucgugcag accugccggg aggagcacaa gaagaagcac cccgacgcca      180

gcgucaacuu cuccgaguuc agcaagaagu gcuccgagcg cuggaagacc augagcgcga      240

aggagaaggg gaaguucgag gacauggcca aggccgacaa ggcccgguac gagcgcgaga      300

ugaagacgua caucccgccc aagggcgaga ccaagaagaa guucaaggac cccaacgccc      360

ccaagcggcc gcccuccgcg uucuuccugu ucugcagcga guaccgcccc aagaucaagg      420

gggagcaccc cggccucucc aucggcgacg uggccaagaa gcugggggag auguggaaca      480

acaccgccgc cgacgacaag cagcccuacg agaagaaggc ggccaagcug aaggagaagu      540

acgagaagga caucgccgcc uaccgggcca agggcaagcc cgacgcggcc aagaaggggg      600

uggucaaggc cgagaagucc aagaagaaga aggaggagga ggaggacgag gaggacgagg      660

aggacgagga ggaggaggag gacgaggagg acgaggacga ggaggaggac gacgacgacg      720

agugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5487
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt1) R6152

<400>  5487
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggacc cuggcccugc      120

uccuguaccu gcaccacgcg aaguggucgc aggccgcccc gacgaccgag ggcgagcaga      180

agagccacga ggucaucaag uucauggacg uguaccagcg gagcuacugc cgccccaucg      240

agacccucgu ggacaucuuc caggaguacc cggacgagau cgaguacauc uucaagccgu      300

cgugcguccc ccugaugcgg ugcgcggggu gcugcaacga cgaggcccug gagugcgugc      360

cgacgagcga gagcaacauc accaugcaga ucaugcggau caagccgcac cagucgcagc      420

acaucggcga gaugagcuuc cuccagcaca gccgcugcga gugccggccc aagaaggacc      480

ggaccaagcc ggagaagaag ucggugcgcg gcaaggggaa gggccagaag cggaagcgga      540

agaagagccg cuucaagagc uggucggucc acugcgagcc gugcagcgag cggcggaagc      600

accuguucgu gcaggacccc cagacgugca agugcagcug caagaacacc gacucgcgcu      660

gcaaggcccg gcagcuggag cucaacgagc ggaccugccg cugcgacaag ccgcggcggu      720

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5488
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt2)

<400>  5488
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg agaccggcuu cgagcacucc ggccucuggg      120

ucuccguccu cgccggccuc cuccucggcg ccugccaggc ccaccccauc cccgacuccu      180

ccccccuccu ccaguucggc ggccaggucc gccagcgcua ccucuacacc gacgacgccc      240

agcagaccga ggcccaccuc gagauccgcg aggacggcac cgucggcggc gccgccgacc      300

agucccccga gucccuccuc cagcucaagg cccucaagcc cggcgucauc cagauccucg      360

gcgucaagac cucccgcuuc cucugccagc gccccgacgg cgcccucuac ggcucccucc      420

acuucgaccc cgaggccugc uccuuccgcg agcgccuccu cgaggacggc uacaacgucu      480

accaguccga ggcccacggc cucccccucc accuccccgg caacaagucc ccccaccgcg      540

accccgcccc ccgcggcccc gcccgcuucc ucccccuccc cggccucccc cccgcccucc      600

ccgagccccc cggcauccuc gccccccagc cccccgacgu cggcuccucc gacccccucu      660

ccauggucgg cggcucccag ggccgcuccc ccuccuacga guccugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5489
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt2)

<400>  5489
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca ccaagcuccu ccccguccuc cuccuccagc      120

acguccuccu ccaccuccuc cuccuccacg ucgccauccc cuacgccgag ggccagaaga      180

agcgccgcaa cacccuccac gaguucaaga aguccgccaa gaccacccuc accaaggagg      240

acccccuccu caagaucaag accaagaagg ucaacuccgc cgacgagugc gccaaccgcu      300

gcauccgcaa ccgcggcuuc accuucaccu gcaaggccuu cgucuucgac aagucccgca      360

agcgcugcua cugguacccc uucaacucca uguccuccgg cgucaagaag ggcuucggcc      420

acgaguucga ccucuacgag aacaaggacu acauccgcaa cugcaucauc ggcaagggcg      480

gcuccuacaa gggcaccguc uccaucacca aguccggcau caagugccag cccuggaacu      540

ccaugauccc ccacgagcac uccuuccucc ccuccuccua ccgcggcaag gaccuccagg      600

agaacuacug ccgcaacccc cgcggcgagg agggcggccc cuggugcuuc accuccaacc      660

ccgagguccg cuacgagguc ugcgacaucc cccagugcuc cgaggucgag ugcaugaccu      720

gcaacggcga guccuaccgc ggccccaugg accacaccga guccggcaag accugccagc      780

gcugggacca gcagaccccc caccgccaca aguuccuccc cgagcgcuac cccgacaagg      840

gcuucgacga caacuacugc cgcaaccccg acggcaagcc ccgccccugg ugcuacaccc      900

ucgaccccga cacccccugg gaguacugcg ccaucaagac cugcgcccac uccgccguca      960

acgagaccga cguccccaug gagaccaccg agugcaucca gggccagggc gagggcuacc     1020

gcggcaccuc caacaccauc uggaacggca uccccugcca gcgcugggac ucccaguacc     1080

cccacaagca cgacaucacc cccgagaacu ucaagugcaa ggaccuccgc gagaacuacu     1140

gccgcaaccc cgacggcgcc gagucccccu ggugcuucac caccgacccc aacauccgcg     1200

ucggcuacug cucccagauc cccaagugcg acgucuccuc cggccaggac ugcuaccgcg     1260

gcaacggcaa gaacuacaug ggcaaccucu ccaagacccg cuccggccuc accugcucca     1320

ugugggacaa gaacauggag gaccuccacc gccacaucuu cugggagccc gacgccucca     1380

agcucaacaa gaacuacugc cgcaaccccg acgacgacgc ccacggcccc uggugcuaca     1440

ccggcaaccc ccucaucccc ugggacuacu gccccaucuc ccgcugcgag ggcgacacca     1500

cccccaccau cgucaaccuc gaccaccccg ucaucuccug cgccaagacc aagcagcucc     1560

gcgucgucaa cggcaucccc acccagacca ccgucggcug gauggucucc cucaaguacc     1620

gcaacaagca caucugcggc ggcucccuca ucaaggaguc cuggguccuc accgcccgcc     1680

agugcuuccc cgcccgcaac aaggaccuca aggacuacga ggccuggcuc ggcauccacg     1740

acguccacga gcgcggcgag gagaagcgca agcagauccu caacaucucc cagcucgucu     1800

acggccccga gggcuccgac cucguccucc ucaagcucgc ccgccccgcc auccucgaca     1860

acuucgucuc caccaucgac cuccccuccu acggcugcac cauccccgag aagaccaccu     1920

gcuccaucua cggcuggggc uacaccggcc ucaucaacgc cgacggccuc cuccgcgucg     1980

cccaccucua caucaugggc aacgagaagu gcucccagca ccaccagggc aaggucaccc     2040

ucaacgaguc cgagcucugc gccggcgccg agaagaucgg cuccggcccc ugcgagggcg     2100

acuacggcgg cccccucauc ugcgagcagc acaagaugcg caugguccuc ggcgucaucg     2160

uccccggccg cggcugcgcc auccccaacc gccccggcau cuucguccgc gucgccuacu     2220

acgccaagug gauccacaag gucauccuca ccuacaagcu cugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5490
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt2)

<400>  5490
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagggcg accccaagaa gccccgcggc aagauguccu      120

ccuacgccuu cuucguccag accugccgcg aggagcacaa gaagaagcac cccgacgccu      180

ccgucaacuu cuccgaguuc uccaagaagu gcuccgagcg cuggaagacc auguccgcca      240

aggagaaggg caaguucgag gacauggcca aggccgacaa ggcccgcuac gagcgcgaga      300

ugaagaccua cauccccccc aagggcgaga ccaagaagaa guucaaggac cccaacgccc      360

ccaagcgccc ccccuccgcc uucuuccucu ucugcuccga guaccgcccc aagaucaagg      420

gcgagcaccc cggccucucc aucggcgacg ucgccaagaa gcucggcgag auguggaaca      480

acaccgccgc cgacgacaag cagcccuacg agaagaaggc cgccaagcuc aaggagaagu      540

acgagaagga caucgccgcc uaccgcgcca agggcaagcc cgacgccgcc aagaagggcg      600

ucgucaaggc cgagaagucc aagaagaaga aggaggagga ggaggacgag gaggacgagg      660

aggacgagga ggaggaggag gacgaggagg acgaggacga ggaggaggac gacgacgacg      720

agugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5491
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt2)

<400>  5491
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc ucuccugggu ccacuggacc cucgcccucc      120

uccucuaccu ccaccacgcc aagugguccc aggccgcccc caccaccgag ggcgagcaga      180

agucccacga ggucaucaag uucauggacg ucuaccagcg cuccuacugc cgccccaucg      240

agacccucgu cgacaucuuc caggaguacc ccgacgagau cgaguacauc uucaagcccu      300

ccugcguccc ccucaugcgc ugcgccggcu gcugcaacga cgaggcccuc gagugcgucc      360

ccaccuccga guccaacauc accaugcaga ucaugcgcau caagccccac cagucccagc      420

acaucggcga gauguccuuc cuccagcacu cccgcugcga gugccgcccc aagaaggacc      480

gcaccaagcc cgagaagaag uccguccgcg gcaagggcaa gggccagaag cgcaagcgca      540

agaagucccg cuucaagucc ugguccgucc acugcgagcc cugcuccgag cgccgcaagc      600

accucuucgu ccaggacccc cagaccugca agugcuccug caagaacacc gacucccgcu      660

gcaaggcccg ccagcucgag cucaacgagc gcaccugccg cugcgacaag ccccgccgcu      720

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5492
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt3)

<400>  5492
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgaug agaccggcuu cgaacacucc gggcuguggg      120

ugucuguccu cgccggacuu cuguugggug cuugccaggc acaucccauc ccugacucaa      180

guccauuacu gcaauuuggc gggcagguua gacagaggua ccuauauaca gaugacgccc      240

agcaaacuga ggcgcaccuc gaaauucggg aggauggaac ggugggcggu gcugccgacc      300

agagcccgga aucccugcuu cagcugaagg cauugaaacc cgggguaaua cagauccucg      360

gagugaagac cucucgcuuc cugugucaac gaccugaugg cgcccuguac ggcucgcucc      420

auuuugaccc agaggcuugc ucauuccgug agagauuacu ggaagauggg uauaacgucu      480

accagagcga ggcacacgga cuucccuugc aucugccugg uaauaaaagu ccacacaggg      540

accccgcccc ucggggccca gcucgcuuuc uaccgcuccc cgggcugccu ccagcccuuc      600

ccgaaccucc aggcauucug gcgccccagc cgccugaugu gggauccucu gaccccuuga      660

gcaugguugg ugggucccag ggaagaucac caaguuauga gagcugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5493
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt3)

<400>  5493
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca ccaagcugcu ccccgugcuu cuguugcagc      120

acgucuuacu gcaucuacuc cugcuucacg uugccauccc uuacgcugag gggcaaaaga      180

agagaaggaa cacacugcau gaguucaaaa agagcgcaaa aacuacguug accaaggagg      240

acccacuccu gaagauuaaa acaaagaaag uaaauuccgc cgaugaaugc gcgaaccggu      300

guauacgcaa ucgaggauuu acuuuuaccu gcaaggcuuu cguguucgac aaaucucgua      360

agagauguua uugguacccg uuuaacucaa ugaguagcgg ugugaagaaa ggcuucgggc      420

acgaguuuga ucuguaugaa aauaaggacu acaucaggaa cugcauuauc ggaaaaggcg      480

guuccuauaa ggggacaguc ucuauuacca aaucgggaau caagugucag cccuggaacu      540

caaugauacc ucaugagcac agcuuccucc caaguuccua ccggggcaaa gauuuacagg      600

agaauuauug ccgcaauccc agaggcgaag aagggggacc uugguguuuu acuucuaacc      660

cagaagugag guacgagguu ugcgacaucc cccaguguag cgagguggaa ugcaugacau      720

guaaugguga guccuaccgg ggcccuaugg aucacaccga aucagggaag acgugccaac      780

gcugggacca gcagacucca caucgacaca aguuccugcc ggagagauau cccgauaaag      840

gauuugacga uaacuacugc aggaauccug acggcaagcc acggcccugg uguuauaccc      900

uugauccuga cacaccaugg gaauacugcg ccauuaaaac uugugcacau agugccguca      960

acgagaccga cgugcccaug gagacaaccg aaugcaucca gggucaaggg gagggauauc     1020

guggcacgag caauacuauu uggaacggca ucccguguca gcgcugggau ucucaguacc     1080

cucacaagca cgacauaaca cccgaaaacu ucaaaugcaa ggauuugaga gagaauuauu     1140

guaggaaccc agacggggcu gaauccccuu ggugcuuuac cacugauccc aauauucggg     1200

uaggauacug uucacagauc ccaaagugcg acguuagcag uggucaagau uguuaccgag     1260

gcaacgggaa aaauuauaug ggaaaccugu cuaagacacg cuccggccua accugcagca     1320

ugugggacaa aaauauggag gaucuccaua gacacauuuu cugggagccc gacgcaucga     1380

agcugaacaa aaauuacugc aggaacccug augacgacgc ccauggucca ugguguuaua     1440

cggggaaucc gcuuaucccc ugggauuacu gcccuaucuc ucggugugaa ggcgacacca     1500

caccaacuau ugugaaccug gaucaccccg ucauauccug cgcuaagacc aagcaguugc     1560

gcguggugaa uggaaucccu acacagacua ccgucggcug gaugguuuca cucaaauaua     1620

gaaacaagca uauuuguggg ggaagucuga ucaaagagag cuggguguua acagccaggc     1680

aaugcuuccc agcgcguaau aaggaccuga aagauuacga agcauggcuc gguauacacg     1740

acguacacga gcggggcgaa gagaagcgaa agcagauucu uaacaucucc cagcuggugu     1800

augggcccga gggaucugau uugguccuac ugaaacucgc cagaccggcu auccuggaca     1860

acuuugugag caccauugau cuuccuucau acggcuguac uaucccagaa aagacgacau     1920

gcaguauuua cgguuggggg uauaccggcc ugauaaaugc cgacggauug cucaggguug     1980

cacaucugua caucaugggc aacgagaaau guucccagca ccaucaaggg aaggugacuu     2040

uaaaugaaag cgagcugugc gcuggagccg agaaaauugg uucuggcccc ugugaagggg     2100

auuauggagg cccucuaauc ugcgagcagc acaagaugcg caugguccuc ggugugaucg     2160

uacccgggcg gggcugcgcg auuccaaaca gaccuggaau auucguuagg guggccuacu     2220

augcaaaaug gauccacaag gucauucuga ccuacaaacu uugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5494
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt3)

<400>  5494
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaggggg accccaaaaa gccuagagga aaaaugagcu      120

ccuacgccuu cuuugugcag accugcaggg aggaacacaa gaaaaagcau ccagaugcuu      180

cugucaacuu cucagaguuu aguaagaaau guagcgaacg guggaagaca auguccgcaa      240

aagagaaggg uaaauucgaa gacauggcca aggcggauaa ggcucgcuau gagcgagaga      300

ugaaaacuua caucccgccc aagggcgaaa cgaaaaagaa auuuaaggac ccuaaugccc      360

caaaacgucc cccuucugca uucuuucugu ucugcucgga guauagacca aagauuaagg      420

gggaacaccc cggacucuca auaggcgaug uugccaagaa acuuggugag auguggaaca      480

auaccgcugc agacgauaaa caaccuuacg agaagaaagc cgcuaagcug aaggaaaaau      540

augagaagga caucgccgcg uacagggcaa aagggaagcc agaugccgcu aaaaagggag      600

ugguaaaggc cgagaaaagc aagaaaaaga aagaagaaga ggaggacgaa gaggaugaag      660

aggacgaaga ggaggaagag gaugaagagg acgaagacga ggaggaagau gacgaugacg      720

agugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5495
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt3)

<400>  5495
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggacc cuugcccugu      120

uguuauaccu gcaucacgcu aagugguccc aggcagcccc cacaacugag ggcgaacaaa      180

aaucucauga ggucaucaag uuuauggacg uuuaucagag aucauacugc aggccuauug      240

aaacgcuagu ggauauauuc caggaguauc cagacgaaau cgaguacauu uuuaaaccga      300

guuguguacc ccucaugcgg ugcgcggggu guugcaauga ugaggcucug gaaugugugc      360

cuaccagcga guccaacauc acaaugcaga uuaugcgcau caagccacac caaucucagc      420

auauaggaga aaugucguuc cuucagcacu cacgaugcga gugucguccc aaaaaggaca      480

gaacuaagcc ugagaaaaag agcgucaggg guaaaggcaa ggggcagaaa cggaagcgca      540

agaaaaguag auuuaagucc uggucugugc acugcgaacc auguagcgag aggcggaaac      600

aucuguucgu ucaagauccc cagaccugca aguguuccug caaaaauaca gacucacgcu      660

gcaaggcccg acaguuggaa cucaacgaga gaaccuguag gugcgauaaa ccucggcguu      720

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5496
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt4)

<400>  5496
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgacg agaccggcuu cgagcacagc ggccuguggg      120

ugagcgugcu ggccggccug cugcugggcg ccugccaggc ccaccccauc cccgacagca      180

gcccccugcu gcaguucggc ggccagguga gacagagaua ccuguacacc gacgacgccc      240

agcagaccga ggcccaccug gagaucagag aggacggcac cgugggcggc gccgccgacc      300

agagccccga gagccugcug cagcugaagg cccugaagcc cggcgugauc cagauccugg      360

gcgugaagac cagcagauuc cugugccaga gacccgacgg cgcccuguac ggcagccugc      420

acuucgaccc cgaggccugc agcuucagag agagacugcu ggaggacggc uacaacgugu      480

accagagcga ggcccacggc cugccccugc accugcccgg caacaagagc ccccacagag      540

accccgcccc cagaggcccc gccagauucc ugccccugcc cggccugccc cccgcccugc      600

ccgagccccc cggcauccug gccccccagc cccccgacgu gggcagcagc gacccccuga      660

gcaugguggg cggcagccag ggcagaagcc ccagcuacga gagcugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5497
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt4)

<400>  5497
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca ccaagcugcu gcccgugcug cugcugcagc      120

acgugcugcu gcaccugcug cugcugcacg uggccauccc cuacgccgag ggccagaaga      180

agagaagaaa cacccugcac gaguucaaga agagcgccaa gaccacccug accaaggagg      240

acccccugcu gaagaucaag accaagaagg ugaacagcgc cgacgagugc gccaacagau      300

gcaucagaaa cagaggcuuc accuucaccu gcaaggccuu cguguucgac aagagcagaa      360

agagaugcua cugguacccc uucaacagca ugagcagcgg cgugaagaag ggcuucggcc      420

acgaguucga ccuguacgag aacaaggacu acaucagaaa cugcaucauc ggcaagggcg      480

gcagcuacaa gggcaccgug agcaucacca agagcggcau caagugccag cccuggaaca      540

gcaugauccc ccacgagcac agcuuccugc ccagcagcua cagaggcaag gaccugcagg      600

agaacuacug cagaaacccc agaggcgagg agggcggccc cuggugcuuc accagcaacc      660

ccgaggugag auacgaggug ugcgacaucc cccagugcag cgagguggag ugcaugaccu      720

gcaacggcga gagcuacaga ggccccaugg accacaccga gagcggcaag accugccaga      780

gaugggacca gcagaccccc cacagacaca aguuccugcc cgagagauac cccgacaagg      840

gcuucgacga caacuacugc agaaaccccg acggcaagcc cagacccugg ugcuacaccc      900

uggaccccga cacccccugg gaguacugcg ccaucaagac cugcgcccac agcgccguga      960

acgagaccga cgugcccaug gagaccaccg agugcaucca gggccagggc gagggcuaca     1020

gaggcaccag caacaccauc uggaacggca uccccugcca gagaugggac agccaguacc     1080

cccacaagca cgacaucacc cccgagaacu ucaagugcaa ggaccugaga gagaacuacu     1140

gcagaaaccc cgacggcgcc gagagccccu ggugcuucac caccgacccc aacaucagag     1200

ugggcuacug cagccagauc cccaagugcg acgugagcag cggccaggac ugcuacagag     1260

gcaacggcaa gaacuacaug ggcaaccuga gcaagaccag aagcggccug accugcagca     1320

ugugggacaa gaacauggag gaccugcaca gacacaucuu cugggagccc gacgccagca     1380

agcugaacaa gaacuacugc agaaaccccg acgacgacgc ccacggcccc uggugcuaca     1440

ccggcaaccc ccugaucccc ugggacuacu gccccaucag cagaugcgag ggcgacacca     1500

cccccaccau cgugaaccug gaccaccccg ugaucagcug cgccaagacc aagcagcuga     1560

gaguggugaa cggcaucccc acccagacca ccgugggcug gauggugagc cugaaguaca     1620

gaaacaagca caucugcggc ggcagccuga ucaaggagag cugggugcug accgccagac     1680

agugcuuccc cgccagaaac aaggaccuga aggacuacga ggccuggcug ggcauccacg     1740

acgugcacga gagaggcgag gagaagagaa agcagauccu gaacaucagc cagcuggugu     1800

acggccccga gggcagcgac cuggugcugc ugaagcuggc cagacccgcc auccuggaca     1860

acuucgugag caccaucgac cugcccagcu acggcugcac cauccccgag aagaccaccu     1920

gcagcaucua cggcuggggc uacaccggcc ugaucaacgc cgacggccug cugagagugg     1980

cccaccugua caucaugggc aacgagaagu gcagccagca ccaccagggc aaggugaccc     2040

ugaacgagag cgagcugugc gccggcgccg agaagaucgg cagcggcccc ugcgagggcg     2100

acuacggcgg cccccugauc ugcgagcagc acaagaugag aauggugcug ggcgugaucg     2160

ugcccggcag aggcugcgcc auccccaaca gacccggcau cuucgugaga guggccuacu     2220

acgccaagug gauccacaag gugauccuga ccuacaagcu gugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5498
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt4)

<400>  5498
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagggcg accccaagaa gcccagaggc aagaugagca      120

gcuacgccuu cuucgugcag accugcagag aggagcacaa gaagaagcac cccgacgcca      180

gcgugaacuu cagcgaguuc agcaagaagu gcagcgagag auggaagacc augagcgcca      240

aggagaaggg caaguucgag gacauggcca aggccgacaa ggccagauac gagagagaga      300

ugaagaccua cauccccccc aagggcgaga ccaagaagaa guucaaggac cccaacgccc      360

ccaagagacc ccccagcgcc uucuuccugu ucugcagcga guacagaccc aagaucaagg      420

gcgagcaccc cggccugagc aucggcgacg uggccaagaa gcugggcgag auguggaaca      480

acaccgccgc cgacgacaag cagcccuacg agaagaaggc cgccaagcug aaggagaagu      540

acgagaagga caucgccgcc uacagagcca agggcaagcc cgacgccgcc aagaagggcg      600

uggugaaggc cgagaagagc aagaagaaga aggaggagga ggaggacgag gaggacgagg      660

aggacgagga ggaggaggag gacgaggagg acgaggacga ggaggaggac gacgacgacg      720

agugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5499
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt4)

<400>  5499
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ugagcugggu gcacuggacc cuggcccugc      120

ugcuguaccu gcaccacgcc aaguggagcc aggccgcccc caccaccgag ggcgagcaga      180

agagccacga ggugaucaag uucauggacg uguaccagag aagcuacugc agacccaucg      240

agacccuggu ggacaucuuc caggaguacc ccgacgagau cgaguacauc uucaagccca      300

gcugcgugcc ccugaugaga ugcgccggcu gcugcaacga cgaggcccug gagugcgugc      360

ccaccagcga gagcaacauc accaugcaga ucaugagaau caagccccac cagagccagc      420

acaucggcga gaugagcuuc cugcagcaca gcagaugcga gugcagaccc aagaaggaca      480

gaaccaagcc cgagaagaag agcgugagag gcaagggcaa gggccagaag agaaagagaa      540

agaagagcag auucaagagc uggagcgugc acugcgagcc cugcagcgag agaagaaagc      600

accuguucgu gcaggacccc cagaccugca agugcagcug caagaacacc gacagcagau      660

gcaaggccag acagcuggag cugaacgaga gaaccugcag augcgacaag cccagaagau      720

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5500
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt5)

<400>  5500
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgaug agaccggcuu cgaacacucc gggcuguggg      120

ugucuguccu cgccggacug cuucugggcg cuugccaggc ccaucccauc ccugacagcu      180

ccccgcuccu gcaauuuggg ggacagguua gacagcggua ccuuuauaca gaugacgcgc      240

agcaaacgga ggcucaccug gaaauucgcg aggauggcac cgugggcgga gccgccgacc      300

agucucccga aagccuccug cagcugaagg cucucaaacc uggcgugauc cagauucugg      360

gcgucaagac auccagauuc cuuugucaac ggcccgaugg ggcccuguac ggaucucucc      420

auuuugaccc ugaggcuugc agcuuccgcg agagacugcu ugaagauggc uauaacgugu      480

accaguccga ggcccacggg cugccccucc aucugccugg aaauaaaagc ccgcaccggg      540

accccgcgcc ucgcggcccc gccagauuuc ugccucuccc cgggcugccg ccugcccuuc      600

ccgaaccucc cggaauccug gcuccccagc cuccggaugu ugggucuucc gacccccuca      660

gcaugguggg cgggucucag ggacgguccc cuagcuauga gucuugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5501
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt5)

<400>  5501
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca ccaagcugcu ccccgugcug cuucugcagc      120

acguccuccu gcaucuucug cuccugcacg uugccauccc uuacgcugag gggcagaaaa      180

agagacggaa cacacugcau gaguucaaaa agagcgccaa aacgacccuc acaaaggaag      240

acccgcugcu uaagauuaaa accaagaaag ucaauuccgc ggaugaaugc gcuaaccgcu      300

guaucagaaa ucggggauuu acauuuaccu gcaaggccuu cguguucgac aaaucucgca      360

agagauguua uugguacccc uuuaacagca uguccucugg cgugaagaaa ggguucggac      420

acgaguuuga ucuguaugaa aauaaggacu acauucggaa cugcaucauu ggcaaagggg      480

gaagcuauaa gggcacagug uccaucacca aaucuggcau caagugucaa ccuuggaaua      540

gcaugauucc ccaugagcac uccuuccucc cuagcucuua ccgcgggaaa gaucugcagg      600

agaacuauug cagaaauccc cggggagaag agggcgggcc uugguguuuu acguccaacc      660

cggaaguucg cuacgaggug ugcgacaucc cccaguguag cgaggucgaa ugcaugaccu      720

guaauggaga gucuuacaga ggcccuaugg aucacacaga auccgggaag accugccaac      780

ggugggacca gcagacaccc caucgccaca aguuccuucc ugagagauau cccgauaaag      840

gauuugacga uaacuacugc cggaauccgg acggcaagcc ucgccccugg uguuauaccc      900

uggauccuga cacgcccugg gaauacugcg ccauuaaaac augugcucau agcgccguga      960

acgagaccga cguucccaug gagacaaccg aaugcaucca gggccaaggg gagggauaua     1020

gaggcaccuc uaauacaauu uggaacggga ucccuuguca gcggugggau ucccaguacc     1080

cgcacaagca cgacauuacg cccgaaaacu ucaaaugcaa ggaucucaga gagaauuauu     1140

gucgcaaccc ugacggagcu gaaagccccu ggugcuuuac cacagauccu aauauccggg     1200

ugggcuacug uucccagauc cccaagugcg acgucucuag cgggcaagau uguuacagag     1260

gaaacggcaa aaauuauaug ggcaaccugu ccaagacccg cagcgggcug acaugcucua     1320

ugugggacaa aaauauggag gaucuccauc ggcacauuuu cugggagccg gacgccucca     1380

agcugaacaa aaauuacugc agaaacccug augacgacgc gcauggaccc ugguguuaua     1440

ccggcaaucc ucuuaucccc ugggauuacu gcccuauuag ccgcugugaa ggggacacga     1500

cacccaccau cgugaaccug gaucacccgg ugauuucuug cgccaagacc aagcagcucc     1560

gggucguuaa uggaaucccu acacagacca cagugggcug gauggugagc cugaaauaua     1620

gaaacaagca uaucuguggg ggcucccuua uuaaagaguc uuggguccug acggcucgcc     1680

aaugcuuccc cgcccggaau aaggaccuca aagauuacga ggcuuggcug ggaauccacg     1740

acgugcacga aagaggcgaa gagaagcgca agcagauucu gaacaucagc cagcucguuu     1800

augggcccga gggauccgau cuggugcuuc ugaaacucgc ccggccugcg auucuggaca     1860

acuuugucag caccaucgau cuuccgucuu acggcuguac aauccccgaa aagaccacau     1920

gcuccauuua cgggugggga uauaccggcc ugaucaaugc cgacgggcuc cugagagugg     1980

cucaucugua cauuaugggc aacgagaaau guagccagca ccaucaagga aagguuacgc     2040

ucaaugaauc ugagcugugc gccggcgcug agaaaaucgg guccggaccu ugugaaggcg     2100

auuauggggg accccuuauu ugcgagcagc acaagaugcg gauggugcug ggcgucaucg     2160

ugccugggcg cggcugcgcc auucccaaca gaccuggaau cuucguccgg guggccuacu     2220

augcuaaaug gauccacaag guuauucuca ccuacaagcu gugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5502
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt5)

<400>  5502
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaggggg accccaaaaa gccuagagga aaaaugagcu      120

ccuacgccuu cuuugugcag accugccggg aggaacacaa gaaaaagcau ccggaugcuu      180

cugucaacuu cagcgaguuu uccaagaaau guucugaacg cuggaagaca augagcgcca      240

aagagaaggg caaauucgaa gacauggcga aggcugauaa ggccagauau gagcgggaga      300

ugaaaacgua cauucccccu aagggggaaa ccaaaaagaa auuuaaggac cccaaugccc      360

cuaaaagacc cccuuccgcu uucuuucugu ucugcucuga guaucgcccg aagaucaagg      420

gagaacaccc cggccucagc aucggggaug uugccaaaaa gcugggagag auguggaaca      480

auacagcugc cgacgauaaa caaccuuacg agaagaaagc ggccaaacuu aaggaaaagu      540

augagaagga cauugcugcc uaccgggcua aaggcaagcc cgaugccgcg aaaaagggcg      600

uggugaaggc cgaaaaaucc aagaaaaaga aagaggaaga ggaggacgaa gaggaugaag      660

aggacgaaga ggaggaagag gaugaagagg acgaagacga ggaggaagau gacgaugacg      720

agugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5503
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt5)

<400>  5503
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggacc cuggcccuuc      120

ugcucuaccu gcaucacgcu aagugguccc aggccgcgcc cacaacggag ggcgaacaaa      180

aaucucauga ggucaucaag uuuauggacg uuuaucagag aagcuacugc cggccuauug      240

aaacccuugu ggauaucuuc caggaguauc cggacgaaau ugaguacauc uuuaaacccu      300

ccugugugcc ucugaugcgc ugcgcugggu guugcaauga ugaggcccuc gaaugugucc      360

ccacaucuga gagcaacauu accaugcaga ucaugagaau caagccucac caaucccagc      420

auauuggaga aaugucuuuc cugcagcaca gccggugcga gugucgcccc aaaaaggaca      480

gaacaaagcc ugagaaaaag uccgugcggg gcaaagggaa gggacagaaa cgcaagagaa      540

agaaaagccg guuuaagucu ugguccguuc acugcgaacc guguagcgag cgcagaaaac      600

aucuguucgu gcaagauccc cagaccugca aguguucuug caaaaauaca gacucccggu      660

gcaaggcccg ccagcucgaa cugaacgaga gaaccugucg gugcgauaaa ccucgcagau      720

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5504
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt6)

<400>  5504
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gauucagaug aaacaggauu ugaacacuca ggauuauggg      120

ucucaguuuu agcaggacua uuacuaggag caugucaagc acauccaaua ccagacucaa      180

gcccauuauu acaauuugga ggacaaguaa gacaaagaua uuuauauaca gaugacgcac      240

aacaaacaga agcacauuua gaaauaagag aagacggcac aguaggagga gcagcagauc      300

aaucaccaga aucacuauua caauuaaaag cauuaaaacc aggaguaaua caaauauuag      360

gaguaaaaac aucaagauuc uuaugccaaa gaccugacgg agcauuauau gguucacuac      420

acuuugaccc agaagcaugu ucauucagag aaagacuacu agaagacgga uauaauguuu      480

accaaucuga agcacaugga uuaccacuac acuuaccagg aaauaaauca ccacaccgag      540

acccagcacc acgaggacca gcaagauucc uaccacuacc aggauuacca ccagcauuac      600

cagaaccacc aggaauacua gcuccacaac caccagacgu aggauccuca gauccauuau      660

caaugguagg aggaucucaa gguagaaguc ccucauacga aucauaagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5505
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt6)

<400>  5505
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggaa caaaacuauu accaguauua uuauuacaac      120

augucuuauu acauuuacuu cuacuacaug uugcaauacc cuaugccgaa ggacaaaaga      180

aaagaagaaa cacucuucac gaguucaaga aaagcgcaaa aacaacauua acaaaagaag      240

acccacuacu aaaaauaaaa acaaagaaag uaaacucagc agaugaaugu gccaacagau      300

guauuagaaa ccgggguuuu acuuuuacau gcaaagccuu cguauucgau aaaucaagga      360

aaagaugcua cugguaucca uucaauucaa ugucauccgg agucaagaaa ggauucggcc      420

augaauuuga ccuauacgaa aauaaagauu auaucagaaa cuguauaaua ggaaaaggug      480

guucauacaa aggaacagua ucaauaacaa aaagcgguau uaaaugucaa cccuggaacu      540

cuaugauucc ucaugaacau ucauuuuuac caucaucaua cagagguaaa gacuuacaag      600

aaaauuacug cagaaaucca aggggagaag aaggcggacc auggugcuuu acaucaaauc      660

ccgaaguaag auaugaagua ugcgacauac cacaauguag ugaaguugaa uguaugacau      720

guaauggaga aagcuacaga gguccaaugg aucauacaga aucaggaaaa acaugccaaa      780

gaugggauca acaaacaccg cauagacaua aauuuuuacc agaaagauau ccagauaaag      840

gauucgauga caauuacugu aggaaucccg acggaaaacc acgaccaugg ugcuauacac      900

uagacccuga uacuccaugg gaauauugcg cuauaaaaac uugugcacau ucagcaguaa      960

acgaaaccga cguaccaaug gaaaccacug aauguauaca agggcaagga gaaggauaca     1020

gaggaacauc aaauacaaua uggaacggaa uacccuguca aagaugggau agccaauauc     1080

cacauaaaca cgacauaacc ccagaaaacu uuaaauguaa agaucuaaga gaaaauuacu     1140

gcagaaaucc cgauggcgca gaaucaccau ggugcuucac aacagauccc aacauaagag     1200

ucggauauug cucccagauu ccuaaaugug auguaagcuc cgggcaagac ugcuaccgag     1260

gcaacgguaa aaauuacaug ggaaacuuaa guaaaacaag aucaggauua acaugcagua     1320

ugugggauaa aaauauggag gacuuacaua gacauauauu cugggaacca gaugcaucaa     1380

aacuuaacaa aaauuauugc agaaacccag acgacgaugc acacggacca ugguguuaua     1440

caggaaaucc acuuauacca ugggacuauu guccaauauc acgaugcgaa ggagauacaa     1500

caccaacaau aguaaacuua gaucauccag uaauaaguug cgcaaaaacu aaacaauuac     1560

gaguuguuaa cggaauacca acacaaacua cagucggaug gaugguuuca uuaaaauaua     1620

gaaacaaaca cauaugcgga ggaucccuua uaaaagaauc cuggguauua acagcaagac     1680

aauguuuucc agccagaaau aaagaucuca aagacuacga agcaugguua ggcauacacg     1740

auguacauga acgaggagaa gaaaaacgaa aacaaauauu aaauauaagc cagcuaguuu     1800

auggaccaga aggaucggac uuaguacuau uaaaacuugc aagaccagca auccuagaca     1860

auuuugucuc aacaaucgac uuacccucau auggaugcac uauuccggag aaaacaacau     1920

gcuccauaua cggaugggga uauacaggau ugauaaaugc agauggauua cuaagaguag     1980

cacaucuaua cauaauggga aaugaaaaau guucacaaca ccaucaagga aaaguaacac     2040

uaaacgaaag cgaauuaugu gcaggcgcag agaaaauagg caguggacca ugugaaggag     2100

auuacggugg accacuaaua ugcgaacaac auaaaaugag aaugguccua ggaguaauag     2160

uccccggaag aggaugugca auaccaaauc gaccgggcau auuuguaaga guagcauacu     2220

acgcaaaaug gauacacaaa guaauacuaa cauacaaacu auaaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5506
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt6)

<400>  5506
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaggag acccaaaaaa accaagagga aaaaugucaa      120

gcuacgcauu cuucguacaa acaugcagag aagaacacaa aaaaaaacac ccagacgcaa      180

gcguaaacuu cagcgaauuc agcaaaaaau guucagaaag auggaaaaca augagcgcaa      240

aagaaaaagg aaaauucgaa gacauggcaa aagcagacaa agcaagauac gaaagagaaa      300

ugaaaacaua cauaccacca aaaggagaaa caaaaaaaaa auucaaagac ccaaacgcgc      360

caaaaagacc accaucagca uucuucuuau ucugcaguga auacagacca aaaauaaaag      420

gagaacaccc aggacuaagu auaggagacg uagcaaaaaa acuaggagaa auguggaaca      480

acacagcagc agacgacaaa caaccauacg aaaaaaaagc agcaaaacua aaagaaaaau      540

acgaaaaaga cauagcggca uacagagcaa aaggaaaacc agacgcagca aaaaaaggag      600

uaguaaaagc agaaaaaagu aaaaaaaaaa aagaagaaga agaagacgaa gaagacgaag      660

aagacgaaga agaagaagaa gacgaagaag acgaagacga agaagaagac gacgacgacg      720

aauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5507
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt6)

<400>  5507
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuau uaagcugggu acacuggaca cuagcacuac      120

uacuauacuu acaccacgcc aaauggagcc aagcagcacc aacaacagaa ggagaacaaa      180

aaucacacga aguaauaaaa uucauggacg uauaccaaag aucauacugu agaccaauag      240

aaacacuagu agacauauuc caagaauacc cagacgaaau agaauacaua uucaaaccau      300

caugcguacc acuaaugaga ugcgcaggau gcugcaacga cgaagcacua gaaugcguac      360

caacaucaga aucaaacaua acaaugcaaa uaaugagaau aaaaccacac caaagucaac      420

acauaggaga aaugaguuuc cuacaacacu caagaugcga augcagacca aaaaaagaca      480

gaacaaaacc agaaaaaaaa ucaguaagag gaaaaggaaa aggccaaaaa agaaaaagaa      540

aaaaaucaag auucaaaagc uggucaguac acugugaacc auguucagaa agaagaaaac      600

accuauucgu acaagaccca caaacaugca aaugcaguug caaaaacaca gacucaagau      660

gcaaagcaag acaacuagaa uuaaaugaac gaacaugcag augcgacaaa ccaagaagau      720

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5508
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt7)

<400>  5508
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgaug agaccggcuu cgaacacucc gggcuguggg      120

ugaguguccu cgccggucug uugcugggcg caugccaggc ccaucccauc ccagacagcu      180

ccccgcuccu gcaauuuggg ggccagguga ggcagcggua cuuguauacu gaugacgcgc      240

agcaaaccga ggcccaccug gaaauucgcg aggaugguac gguagggggc gcagccgacc      300

agagucccga aagccuccug cagcugaagg cacucaaacc aggcgugauc cagauucugg      360

gggucaagac uuccagguuc uugugucaac ggcccgaugg ugcccuguac ggcagccucc      420

auuuugaccc agaggcgugc uccuuccgcg agaggcugcu ggaagauggg uauaacgugu      480

accagaguga ggcccacggc uugccccucc aucugccagg uaauaaaagc ccgcaccggg      540

accccgcacc acgcgggccc gccagguuuc ugccacuccc cggccugccg cccgccuugc      600

cagaaccccc aggcauccug gcaccccagc caccggaugu gggguccagc gacccccuca      660

guauggucgg uggcucccag gggcggagcc cauccuauga gaguugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5509
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt7)

<400>  5509
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca ccaagcugcu ccccgugcug uugcugcagc      120

acguccuccu gcauuugcug cuccugcacg uggccauccc auacgcagag gggcagaaaa      180

agaggcggaa cacucugcau gaguucaaaa agagcgccaa aaccacgcuc acuaaggagg      240

acccgcuguu gaagauuaaa accaagaaag uaaauuccgc ggaugaaugc gccaaccgcu      300

guaucaggaa ucgggguuuu accuucacuu gcaaggcauu uguguucgac aaaagucgca      360

agagguguua uugguacccc uuuaacagca uguccagugg cgucaaaaag ggguucggcc      420

acgaguuuga ucuguaugaa aauaaggacu acauucggaa cugcaucauu gguaaagggg      480

gcagcuauaa gggcaccgug uccaucacga aaagcgggau caagugucaa ccauggaacu      540

ccaugauucc ccaugagcac aguuuccucc caagcuccua ccgcgguaaa gaucugcagg      600

agaauuauug caggaauccc cggggcgaag aagggggccc augguguuuu acuagcaacc      660

cggaagugcg cuacgagguc ugcgacaucc cccaguguag ugagguggaa ugcaugaccu      720

gcaaugguga guccuacagg gggccaaugg aucacacuga aagcggcaag accugucaac      780

ggugggacca gcagacuccc caucgccaca aguuccugcc agagagguau cccgauaaag      840

gcuuugacga uaacuacugc cggaauccgg acgggaagcc ccgcccaugg uguuauacgu      900

uggaucccga cacuccaugg gaauacugcg ccauuaaaac cugugcacau uccgccguaa      960

acgagacuga cgugcccaug gagaccaccg aaugcaucca gggucaaggc gagggguaua     1020

ggggcaccag uaauacgauu uggaacggua ucccauguca gcggugggau agccaguacc     1080

cgcacaagca cgacauuacc cccgaaaacu ucaaaugcaa ggaucuccgc gagaauuauu     1140

guaggaaccc agacggcgcg gaaucccccu ggugcuucac uaccgaucca aauauccggg     1200

ucggguacug cagccagauc cccaagugug acgugaguuc cggccaagau ugcuacaggg     1260

ggaacgguaa aaauuauaug ggcaaccuga gcaagacccg cagugggcug acuuguucca     1320

ugugggacaa aaauauggag gaucuccauc ggcacaucuu uugggagccg gacgccagca     1380

agcugaacaa aaauuacugc aggaacccag augacgacgc acauggcccc ugguguuaua     1440

cggguaaucc cuugauucca ugggauuacu gccccauuag ccgcugugaa ggcgacacca     1500

cuccaaccau cgugaaccug gaucacccgg ucauuuccug cgccaagacc aagcagcucc     1560

gggugguaaa ugggaucccc acucagacga ccgugggcug gauggucagu cugaaauaua     1620

ggaacaagca uaucuguggg ggcagccuga uuaaagaguc cuggguguug acugcccgcc     1680

aaugcuuccc agcacggaau aaggaccuca aagauuacga agccuggcug gguauccacg     1740

acgugcacga gaggggcgaa gagaagcgga aacagauucu gaacaucagc cagcucgucu     1800

augggcccga ggguagugau cugguguugc ugaagcucgc gcgcccagcc auucuggaca     1860

acuuuguauc caccaucgau cugcccagcu acggcuguac uaucccggaa aagaccacgu     1920

gcuccauuua cggguggggc uauaccgggu ugaucaaugc agacggccuc cugagggugg     1980

cccaucugua cauuaugggu aacgagaaau gcagucagca ccaucaaggg aaggucacuc     2040

ucaaugaaag cgagcugugu gcaggcgccg agaaaaucgg cuccgggcca ugcgaaggug     2100

auuauggcgg gcccuugauu ugugagcagc acaagaugcg gauggugcug ggcgucaucg     2160

ugccaggucg cgggugcgcc auucccaaca ggccgggcau cuucgugcgg guagcguacu     2220

augcaaaaug gauccacaag gugauucuca ccuacaagcu gugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5510
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt7)

<400>  5510
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaggggg accccaaaaa gccaaggggu aaaaugagcu      120

ccuacgccuu cuuugugcag accugccggg aggaacacaa gaaaaagcau ccggaugcaa      180

gugucaacuu cagcgaguuu uccaagaaau guagugaacg cuggaagacu augagcgcca      240

aagagaaggg caaauucgaa gacauggcga aggccgauaa agcaagguau gagcgggaga      300

ugaagaccua cauuccccca aagggggaaa cgaaaaagaa auuuaaggac cccaaugccc      360

caaaaaggcc cccauccgca uucuuucugu ucugcagcga guaucgcccg aagaucaagg      420

gcgaacaccc cggucucucc aucggggaug uggccaaaaa gcugggcgag auguggaaca      480

auacugcggc cgacgauaaa caaccauacg agaagaaagc agccaaguug aaggaaaaau      540

augagaagga cauugccgca uaccgggcca aaggcaagcc cgaugcggcc aaaaaggggg      600

uagugaaggc agagaaaagu aagaaaaaga aagaagaaga ggaggacgaa gaggaugaag      660

aggacgaaga ggaggaagag gaugaagagg acgaagacga ggaggaagau gacgaugacg      720

agugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5511
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt7)

<400>  5511
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggacc cuggccuugc      120

ugcucuaccu gcaucacgca aagugguccc aggccgcgcc cacuaccgag ggcgaacaga      180

aaagucauga ggucaucaag uuuauggacg uguaucaaag gagcuacugc cggccaauug      240

aaacguuggu agauaucuuc caggaguauc cggacgaaau ugaguacauc uuuaaacccu      300

ccugugugcc acugaugcgc ugcgccgggu guugcaauga ugaggcacuc gaaugugucc      360

ccaccaguga gagcaacauu acuaugcaga ucaugaggau caagccacac caaucccagc      420

auauugguga aaugagcuuc cugcagcacu cccggugcga gugucgcccc aaaaaggaca      480

ggaccaagcc agagaaaaag agugugcggg gcaaagggaa gggccagaaa cgcaagagga      540

aaaagagccg guuuaagucc uggagcgugc acugcgaacc guguagugag cgcaggaaac      600

aucuguucgu ccaagauccc cagacuugca agugcuccug uaaaaauacc gacagccggu      660

gcaaggcccg ccagcucgaa cugaacgaga ggacgugucg gugcgauaaa ccaaggcgcu      720

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5512
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt8)

<400>  5512
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucugacg aaaccggcuu cgaacacucc ggacucuggg      120

ucuccguccu cgccggccuc cuccuaggcg ccugccaagc ccaccccauc cccgacucau      180

ccccacuccu acaauucggc ggccaagucc gucaacgcua ccucuauacc gaugacgccc      240

aacaaaccga agcccaccuc gaaauccgcg aagacggaac cgucggcggc gccgcugacc      300

aaucacccga aucccuccuc caacucaaag cacucaaacc cggcguaauc caaauccucg      360

gcguaaaaac cucacgauuu cuaugucaaa gacccgacgg agcccuauac ggcucucuac      420

acuucgaccc agaagcaugc uccuuccgcg aacgacuccu cgaagacgga uacaacgucu      480

accaaucaga agcccacggc cuaccccucc accuccccgg caacaaaucu ccccaccgcg      540

accccgcacc ccgcggcccc gcccgcuucc ucccccuccc cggccuaccc ccagcccuac      600

ccgaaccacc cggcauacuc gcaccccaac cacccgacgu cggcuccucc gacccccuau      660

ccauggucgg cggcucccaa ggccgcuccc ccucauacga aucuuaagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5513
<211>  2269
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt8)

<400>  5513
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca cgaaacugcu cccaguauug cucuugcaac      120

acguccuacu ccaccuucua cugcuacacg ucgcuauacc cuaugccgaa ggacaaaaga      180

aacgucgcaa cacccuacac gaauuuaaga aaagcgccaa gaccacacuc acuaaagaag      240

auccccuacu caaaauaaag accaaaaagg ugaacucggc ugacgaaugc gccaaccgau      300

gcauccgaaa cagaggcuuc acuuuuaccu gcaaagccuu cguuuucgac aagagccgaa      360

aacgaugcua cugguaccca uucaacagca uguccuccgg gguaaagaaa ggcuucggac      420

augaguucga ucuauacgaa aauaaagacu acauaagaaa cugcauaauc ggcaaaggag      480

gguccuacaa aggcacaguc agcaucacaa agucagggau caaaugccaa cccuggaacu      540

ccaugauacc acacgagcac aguuuccucc cuaguagcua ccgaggaaaa gaccuccagg      600

agaacuacug ccgcaacccc cgcggggaag aaggcggacc uuggugcuuc acaagcaacc      660

ccgagguccg cuacgagguc ugcgacaucc cccaaugcag cgaagucgag ugcaugaccu      720

guaacggaga aucauaccga ggcccaaugg aucacaccga auccggaaaa acaugccaac      780

gaugggacca acaaacaccg caccgacaca aguuccuccc cgaacgguac cccgacaaag      840

gauucgacga caacuacugc cgcaaccccg acggaaaacc acgaccaugg ugcuacacgc      900

ucgacccgga cacccccugg gaauacugcg ccaucaaaac cugcgcacac ucagcgguga      960

acgaaaccga uguaccaaug gaaacaaccg aaugcaucca aggacaagga gagggcuaca     1020

ggggcacguc aaauaccauc uggaacggca uaccaugcca gcgcugggac agucaguacc     1080

cccacaaaca cgacauaacc cccgaaaacu ucaaaugcaa agaccucaga gaaaacuacu     1140

gccgcaaccc cgacggcgcc gaaucccccu gguguuucac aaccgaccca aacauccgcg     1200

ugggcuacug cucacaaauc cccaagugcg acguaucaag cggccaagac ugcuaucgcg     1260

ggaacggcaa aaacuacaug ggaaaccucu caaagaccag aagcggccua acaugcucaa     1320

ugugggacaa aaacauggag gaccuccacc ggcacaucuu uugggaaccc gacgcuucca     1380

aacucaacaa aaacuacugc cgaaaccccg acgacgaugc acacggccca uggugcuaca     1440

caggcaaccc ccugauaccc ugggacuacu gccccaucuc cagaugcgag ggcgacacaa     1500

caccgaccau cguaaaucuc gaccaccccg uaaucuccug cgccaaaaca aaacaacuaa     1560

gggucgugaa cggaaucccc acccaaacaa cagugggcug gauggucagc cucaaauaca     1620

gaaacaagca caucugcggc ggcucccuca ucaaggaaag cuggguacua acagccaggc     1680

aaugcuuccc cgccagaaau aaagaucuaa aagacuacga agccuggcua ggcauccaug     1740

acguccacga acgcggcgag gagaaacgaa aacaaauucu caacaucucu caacucgucu     1800

auggaccaga agggagcgac cucguucuuc ugaaacucgc ccggcccgca aucuuagaca     1860

acuucgucag cacaaucgac cuccccucau acggaugcac caucccagaa aagacaaccu     1920

gcagcauaua cggauggggc uacaccggcc ugaucaacgc agacggccuu cucagagucg     1980

cccaucucua caucauggga aacgaaaaau gcagccaaca ccaccaaggc aaaguaacgc     2040

ucaacgaauc cgaacucugc gccggagcag ggacuagucc cuguucccag agcccacuuu     2100

uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2220

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2269


<210>  5514
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt8)

<400>  5514
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaaagggg acccgaaaaa gccaagagga aagaugucga      120

gcuaugccuu uuucgugcaa acgugcaggg aagaacacaa gaaaaagcac ccggacgcga      180

gcgugaacuu uagcgaguuc ucgaaaaagu gcucagaaag guggaagacc augagcgcga      240

aagaaaaagg gaaauuugaa gauauggcaa aagcggacaa ggcaagguac gagcgagaaa      300

ugaagacaua uaucccgcca aagggcgaga caaagaagaa auucaaagac ccgaacgcgc      360

ccaagcgccc gccaucggcc uuuuuccuau ucugcagcga guacaggccc aagauaaagg      420

gcgagcaccc aggauugagc auaggcgaug ucgcgaaaaa gcuaggggaa auguggaaca      480

acacggccgc ggacgauaaa cagccguaug aaaagaaagc ggccaagcuc aaggaaaagu      540

acgagaaaga uaucgcggcc uauagagcga aaggaaaacc ggacgcggcc aagaaagggg      600

uagugaaagc ggaaaagagc aagaaaaaga aagaggaaga ggaagaugaa gaggacgagg      660

aagacgaaga ggaagaggaa gaugaagagg acgaggacga ggaagaggac gaugacgaug      720

aauagggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5515
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt8)

<400>  5515
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc ucuccugggu ccacuggacc cucgcccucc      120

uccucuaccu ucaccacgca aaaugguccc aagccgcccc caccaccgaa ggagaacaaa      180

aaucccacga agucauaaaa uucauggacg uauaccaacg aucauacugc cgacccaucg      240

aaacccuagu cgacaucuuc caagaauacc cagacgaaau cgaauacaua uucaaacccu      300

ccugcguacc ccucaugcgc ugcgccggcu gcugcaacga cgaagcccua gaaugcgucc      360

caacaucaga aucaaacauc accaugcaaa ucaugcgcau caaaccacac caaucccaac      420

acauaggcga aauguccuuc cuccaacacu cacgcugcga augccgcccc aaaaaagacc      480

gaaccaaacc cgaaaaaaaa ucaguccgag gcaaaggaaa aggccaaaaa cgcaagcgca      540

aaaaaucccg cuucaaaucc ugguccgucc acugcgaacc cugcuccgaa cgccgaaaac      600

accucuucgu ccaagaccca caaaccugca aaugcuccug caaaaacacc gacuccagau      660

gcaaagcacg ccaacucgaa cucaacgaaa gaaccugccg cugcgacaaa ccccgccgcu      720

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5516
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) (opt9)

<400>  5516
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg aaaccggauu cgaacacuca ggccucuggg      120

ucucaguccu cgccggccuc cuccucggag ccugccaagc ccacccaauc cccgacuccu      180

caccacuccu ccaauucggc ggccaagucc gacaacgaua ccucuacacc gacgacgccc      240

aacaaaccga agcccaccuc gaaauccgcg aagacggcac aguaggaggc gccgccgacc      300

aaucacccga aucccuacuc caacuaaaag cacucaaacc cggcgucauc caaauacucg      360

gcgucaaaac cucaagauuc cucugccaac gccccgacgg cgcccucuac ggcucccucc      420

acuucgaccc cgaagccugc uccuuccgcg aacgccuccu cgaagacggc uacaacgucu      480

accaauccga agcccacggc cucccccucc accucccagg caacaaaucc ccacaccgcg      540

accccgcacc ccgcggccca gcccgcuucc ucccccuccc cggacuaccc ccugcccuac      600

ccgaaccacc aggcauccuc gcaccccaac cacccgacgu cggcuccucc gacccccucu      660

caaugguagg cggcucacaa ggccgauccc ccuccuacga auccuaagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5517
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt9)

<400>  5517
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggca caaaacuccu uccgguacug cugcuacaac      120

acgugcuucu ccaccuccuu cuacuccacg ucgcaauccc cuaugcagaa gggcagaaaa      180

agcgacgcaa cacacuccac gaguucaaga aaucggccaa aacaacccua accaaagagg      240

acccccuccu caaaaucaaa accaagaaag uaaacuccgc cgacgagugc gccaacagau      300

gcauccgcaa ccggggcuuc accuucacau gcaaagccuu cguguucgau aaaagccgca      360

aacgaugcua cugguaccca uucaacucca ugagcucggg aguuaagaaa ggcuuuggcc      420

acgaauuuga ccuauacgag aauaaagacu acauaagaaa cugcaucauc gguaaaggcg      480

gcucauacaa agggaccgua uccaucacaa aaagcggaau aaaaugccaa ccguggaacu      540

cuaugauacc ccacgaacac ucauuccuac cauccucaua ccgcggcaaa gaccuacaag      600

agaacuacug ccgaaacccc cgaggagaag aagggggacc auggugcuuc accucaaacc      660

cagagguacg guacgaaguc ugcgacaucc cacaaugcag cgaaguagag ugcaugaccu      720

guaacggaga guccuaccgg ggaccaaugg accauaccga aucgggaaaa acuugccaac      780

gaugggauca acaaacaccc caucgucaca aauuccuacc ggaacgauac ccagacaaag      840

gauucgacga caacuacugc agaaaucccg acgguaaacc cagaccuugg ugcuacaccc      900

uagaccccga caccccaugg gaauacugcg ccauaaagac cugcgcacac ucugccguca      960

acgagaccga cguccccaug gaaacaaccg aaugcauaca ggggcaggga gagggcuacc     1020

gcggcaccag caacaccauc uggaacggua uacccugcca gcgaugggac agccaauacc     1080

cccacaagca cgacauaacc ccugagaacu ucaagugcaa agaccuacgc gaaaacuacu     1140

gccgaaaccc agacggcgcc gaaucaccau gguguuucac aacagaccca aacauccgcg     1200

ucggcuacug cucccaaaua cccaaaugcg acgucaguuc cggacaagac ugcuaccgag     1260

gcaacggaaa gaacuacaug ggaaaccucu ccaaaacccg uagcgguuua acaugcucca     1320

ugugggacaa gaacauggaa gaccuacaca gacauauauu cugggaaccc gacgcaagca     1380

aacucaacaa aaauuacugc cgcaaccccg acgacgaugc ccauggcccc uggugcuaca     1440

ccggcaaccc ccugaucccc ugggacuacu guccaauaag ccgaugcgag ggggacacca     1500

ccccuaccau cgucaaccug gaccaccccg ucaucuccug cgcaaaaacc aaacagcucc     1560

gaguagugaa cggcauccca acccagacaa cggucggaug gauggucuca cuaaaauacc     1620

gaaacaaaca cauaugcggu ggaucccuca ucaaagaaag cugggucuua accgcccgcc     1680

aaugcuuccc cgcacgaaac aaagaccuaa aagacuacga agcauggcua ggcauccacg     1740

acguacacga acgaggcgaa gaaaaacgaa agcaaauccu caacaucuca caguuagucu     1800

acggaccaga agguucagac cucgugcucc uaaaguuagc ccgccccgcc auacuagaca     1860

acuucgucag caccaucgac cuaccaucau acggaugcac cauaccagag aaaaccacau     1920

gcaguaucua cggcuggggc uacacgggcc ucaucaacgc cgacggccuc cuacgcguag     1980

cccaccucua uaucaugggc aacgaaaaau gcucacaaca ccaccaaggg aaaguaacac     2040

ugaacgaauc cgagcucugc gccggcgccg agaaaaucgg auccggcccc ugcgaaggag     2100

acuacggggg accacuaaua ugcgaacagc acaagaugcg aaugguccuc ggagucaucg     2160

uacccggccg aggcugcgca auacccaauc gccccggcau auucguucgc guagccuacu     2220

acgcuaaaug gauccacaaa gucauacuca ccuacaaacu auaaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5518
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt9)

<400>  5518
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaaagggg acccgaagaa accaagggga aaaaugucga      120

gcuaugccuu cuucgugcaa acgugcaggg aggaacacaa gaaaaagcac ccagacgcga      180

gcgugaacuu uagcgaguuc ucgaaaaagu gcucggaaag guggaagaca augagcgcga      240

aagagaaagg gaaauuugaa gauauggcga aagcggacaa ggccagguac gagcgagaga      300

ugaagaccua uaucccgccc aagggcgaga caaagaagaa auucaaagac ccgaacgcgc      360

caaagcgccc gcccucggca uuuuucuugu ucuguagcga guacaggcca aagaucaagg      420

gcgagcaccc aggcuugagc auaggcgaug ucgccaaaaa gcucggggaa auguggaaua      480

acacagcagc agacgauaaa cagcccuaug aaaagaaagc ggcaaagcuc aaggaaaagu      540

acgagaaaga uaucgcggcc uaucgcgcga aagggaaacc ggacgcggca aagaaagggg      600

ucgugaaagc ggaaaagagc aagaaaaaga aagaggaaga ggaagaugaa gaggacgagg      660

aagaugaaga ggaagaggaa gaugaagagg acgaggacga agaagaggac gaugacgaug      720

aauagggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5519
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt9)

<400>  5519
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc ucuccugggu ccacuggaca cucgcccucc      120

uccuauaccu acaccacgcc aaauggagcc aagccgcccc cacaaccgaa ggcgaacaaa      180

aaucccacga agucaucaaa uucauggacg ucuaccaacg cuccuacugc cgccccaucg      240

aaacccucgu cgacaucuuc caagaauacc ccgacgaaau cgaauacauc uucaaacccu      300

ccugcguccc ccucaugcgc ugcgccggcu gcugcaacga cgaagcccuc gaaugcgucc      360

ccaccucaga aucaaacaua acaaugcaaa ucaugcgcau caaaccccac caaucccaac      420

acaucggaga aauguccuuc cuccaacacu cacgcugcga augccgccca aaaaaagacc      480

gcaccaaacc cgaaaaaaaa uccguacgcg gcaaaggcaa aggccaaaaa cgcaaacgca      540

aaaaaucccg cuucaaauca uggucagucc acugcgaacc cugcagcgaa cgacgcaaac      600

accucuucgu ccaagaccca caaacaugca aaugcuccug caaaaacaca gacucgcgcu      660

gcaaagcccg ccaacucgaa cuaaacgaac gcaccugccg cugcgacaaa ccccgacgcu      720

agggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5520
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) 
       (opt11)

<400>  5520
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg aaaccggcuu cgaacacucc ggccucuggg      120

ucuccguccu cgccggccuc cuccuaggcg caugccaagc ccaccccaua cccgacuccu      180

caccccuccu ccaauucggc ggccaagucc gccaacgcua ccuauacacc gacgacgccc      240

aacaaacaga agcccaccuc gaaauccgag aagacggcac agucggcggc gccgccgacc      300

aaagccccga aucccuccuc caacucaaag cccucaaacc cggcgucauc caaauccucg      360

gcgucaaaac aucccgcuuc cuaugccaac gccccgacgg cgcccucuac ggcucacucc      420

acuucgaccc cgaagccugc uccuuccgcg aacgccuccu cgaagacggc uacaacgucu      480

accaauccga agcccacggc cuaccccuac accuccccgg caacaaaucc ccucaccgcg      540

accccgcacc ccgcggcccc gcccgcuucc uaccccuccc cggccucccc cccgcccuac      600

ccgaaccccc cggcauccuc gccccccaac ccccagacgu cggcuccucu gacccccucu      660

ccauggucgg cggcucccaa ggccgcucac ccuccuacga auccuaagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5521
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt11)

<400>  5521
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggaa caaaauuacu accaguccua cuacuccaac      120

acguccuacu ccaccuacua cuacuccacg ucgcaauccc cuacgccgaa ggacagaaaa      180

agcgaagaaa cacacuacac gaauuuaaga aaucagccaa aaccacccua accaaagaag      240

acccccuacu gaaaaucaaa acuaagaaag ucaacuccgc agaugagugc gcaaaccgau      300

gcauacgcaa ccgcggcuuc acauucacuu gcaaagccuu cguuuucgac aaaucacgaa      360

aacgcugcua cugguacccc uuuaacucga ugagcucagg cgugaagaaa ggcuucggcc      420

augaguucga ccuauacgaa aauaaagauu acauacguaa cugcaucauc ggaaaaggug      480

gcagcuacaa aggcacuguc ucaauaacga aaaguggcau caaaugccaa cccuggaacu      540

ccaugauccc ucacgaacac ucauuccucc ccuccagcua cagagggaaa gaccuacaag      600

aaaacuacug ccguaaucca agaggagaag aaggcggacc uuggugcuuc accuccaacc      660

ccgaaguaag auacgaagug ugcgacauac cacaaugcuc cgaagucgaa ugcaugaccu      720

gcaacggcga auccuaccga ggacccaugg accacaccga aucagguaag accugccaac      780

gcugggacca acaaacaccc cacagacaca aauuccuccc ugaacgcuac cccgacaaag      840

gcuucgacga caacuacugc aggaacccag acgguaaacc ccgacccugg uguuacaccc      900

ucgacccaga uacacccugg gaauacugcg ccauaaaaac augcgcacac uccgccguca      960

acgagacaga cguccccaug gaaaccaccg agugcauaca aggacaaggg gaaggauaca     1020

gaggaacauc aaacaccauu uggaacggca uacccugcca aagaugggac ucccaguauc     1080

cccacaaaca cgacaucaca ccagaaaacu ucaaaugcaa ggaccuacga gaaaacuacu     1140

gccgcaaccc agacggagcu gaaucccccu ggugcuucac aacagacccg aauauccgcg     1200

ucggauacug uucgcaaauc ccaaagugcg acgucagcuc aggacaagac ugcuacagag     1260

gaaacggcaa gaacuauaug ggcaaccuuu cgaaaacacg cagcggccua accugcucca     1320

ugugggacaa gaacauggaa gaccuccacc ggcacauauu cugggaaccc gacgcaagua     1380

aacuuaacaa aaacuacugu cgcaauccgg acgacgacgc ccacggcccu uggugcuaca     1440

ccgguaaccc ccuaaucccg ugggacuacu gccccauauc ccgaugcgaa ggagauacaa     1500

cacccaccau cgugaaccua gaccaccccg ucaucucaug cgcuaaaacg aaacagcucc     1560

gagucgucaa cggcauccca acgcaaacga ccgucggaug gauggucucc cugaaauacc     1620

gcaacaaaca cauaugcggc ggaagccuaa uaaaagaaag cuggguccuu acagcccggc     1680

aaugcuuccc agcccguaac aaagaccuca aagacuacga agccuggcuc ggcauccacg     1740

acguacauga acgaggggaa gaaaaacgca aacaaauacu caacaucucc cagcugguau     1800

acggcccgga aggaagcgac cucguccucu ugaaacuagc cagacccgcc auacuagaca     1860

acuucgucag caccaucgac cuccccucau acggcugcac caucccagaa aagacaaccu     1920

gcucaaucua cggcuggggc uacaccggac uaaucaacgc cgacggacuc cugcgggucg     1980

cccauuugua caucauggga aacgaaaaau gcucccaaca ccaccaaggc aaagucaccc     2040

ugaacgaauc cgaacucugc gcaggcgccg agaaaaucgg aucaggaccc ugcgaagggg     2100

acuacggggg cccccucauc ugcgagcaac auaaaaugcg uauggugcua ggcgugaucg     2160

uccccggacg cggaugcgcc aucccgaacc gccccgggau cuucguccgc gucgccuacu     2220

acgccaaaug gauacauaaa gucauucuca ccuacaagcu guaaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5522
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt11)

<400>  5522
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaaagggg acccgaaaaa gccgagggga aagaugucga      120

gcuaugccuu cuucgugcaa acgugcaggg aggaacacaa gaaaaagcac ccggacgcga      180

gcgugaacuu cagcgaguuc ucgaaaaagu gcucggaaag guggaagacc augagcgcga      240

aagagaaagg gaaauuugaa gauauggcga aagcggacaa ggcaagguac gagcgagaga      300

ugaagacaua uauaccacca aagggcgaga ccaagaaaaa guucaaggac ccgaacgcgc      360

ccaagcgccc gccaucggcc uuuuucuugu ucuguagcga guacaggccc aagaucaagg      420

gagagcaccc gggcuugagc auaggcgacg ucgcgaaaaa gcucggggaa auguggaaua      480

acacggccgc ggacgauaaa cagccauaug aaaagaaagc ggccaagcua aaggaaaagu      540

acgagaaaga uaucgcggca uaucgcgcga aagggaaacc ggacgcggcc aagaaaggag      600

ucguaaaagc ggaaaagagc aagaaaaaga aagaggaaga ggaagaugaa gaggacgagg      660

aagaugaaga ggaagaggaa gaugaagagg acgaggacga ggaagaggac gaugacgaug      720

aauagggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5523
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt11)

<400>  5523
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc uauccugggu ccacuggaca cucgcccucc      120

uccucuaccu ccaccacgcc aaaugguccc aagcagcacc caccacagaa ggcgaacaaa      180

aaucccacga agucaucaag uucauggacg ucuaccaacg cucauacugc cgccccaucg      240

aaacacucgu agacaucuuc caagaauacc ccgacgaaau cgaauacauc uucaaacccu      300

ccugcguccc acuaaugcgc ugcgccggau gcugcaacga cgaagcccuc gaaugcgucc      360

caaccuccga auccaacauc accaugcaaa ucaugcgcau caaaccccac caaucccaac      420

acaucggcga aauguccuuc cuccaacacu cccgcugcga augccgcccc aaaaaagacc      480

gcaccaaacc cgaaaaaaaa ucaguccgcg gcaaaggcaa aggucaaaaa cgaaaacgca      540

aaaaaucacg cuucaaaucc ugguccgucc acugcgaacc cugcucagaa cgacgcaaac      600

accucuucgu ccaagacccc caaaccugca aaugcucaug caaaaacacc gacucccgau      660

gcaaagcccg ccaacucgaa cucaacgaac gaaccugccg cugcgacaaa ccccgacgcu      720

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5524
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) 
       (opt12)

<400>  5524
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucugacg aaacagguuu cgaacacuca ggacuauggg      120

ucucaguauu agcaggacua uuauuaggag caugucaagc acauccaaua ccagacucau      180

caccacuacu acaauucggc ggacaaguaa gacaaagaua cuuauacaca gacgaugcac      240

aacaaacaga agcacauuua gaaauaagag aagauggcac aguaggcgga gcagcagacc      300

aaucaccaga aucacuauua caauuaaaag cauuaaaacc aggaguaaua caaauauuag      360

gaguaaaaac aucaagauuc uuaugucaaa gaccugacgg agcacuauac ggaucacuac      420

acuuugaccc agaagcaugc ucauuuagag aaagauuauu agaagacgga uacaauguau      480

aucaaucaga agcacacgga uuaccauuac acuuacccgg aaauaaauca ccacauagag      540

acccagcacc aagaggaccu gcaagauuuc uaccucuacc aggacuacca ccagcacuac      600

cugaaccacc aggaauauua gcaccacaac caccagacgu aggauccuca gaccccuuau      660

caaugguagg cggaucacaa ggaagaucac caucauauga aucauaagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5525
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt12)

<400>  5525
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggaa cuaaauuacu accaguucua uuacuucaac      120

acguccuauu acauuuauua cuauuacacg uugcaauacc auaugcagaa ggacaaaaaa      180

aaagaaggaa caccuuacac gaauuuaaaa aaucggcaaa aacaacccuc acaaaggaag      240

acccacuauu aaaaaucaaa acaaaaaaag ugaauagugc agacgaaugu gcaaauagau      300

gcauaagaaa cagaggauuu acauucacuu guaaagcauu uguauuugau aaaucaagga      360

aaagguguua uugguauccu uuuaacucaa ugucuagugg aguaaaaaaa ggauucggac      420

augaauuuga ccuauaugaa aauaaagacu auauaagaaa uugcauaaua ggaaaaggug      480

gaucauauaa agggacaguu agcauaacca aaucaggcau aaaaugucaa ccauggaauu      540

caaugauacc acaugaacau uccuuucuac cuaguaguua ucguggaaaa gauuuacaag      600

aaaauuauug uagaaaccca agaggagaag aaggagggcc auggugcuuu acaagcaacc      660

cagaagucag auaugaagua ugugacauac cacaauguuc agaaguagaa uguaugacau      720

gcaauggaga aucguauaga gguccaaugg accauacaga aucaggaaaa acaugucaaa      780

gaugggauca acaaacccca caucgacaua aauucuuacc agaacgauau ccagacaaag      840

gguucgacga uaauuauugc agaaauccag augggaaacc aagacccugg uguuacacuc      900

uagaccccga uacaccaugg gaauauugug caauaaaaac augcgcacac ucagcaguaa      960

augagacuga ugucccaaug gaaacuacag aaugcauuca aggacaaggu gaagguuacc     1020

gaggcacaag uaauacuaua uggaauggga uaccauguca aagaugggac agucaauacc     1080

cacauaaaca ugauauaacg ccagaaaauu uuaaauguaa agauuuaaga gaaaauuauu     1140

gcagaaaucc ugauggcgcg gaaaguccau ggugcuucac aacugauccu aacauaagag     1200

uugguuauug cagucaaaua ccuaaaugcg auguaucauc cggacaagau uguuauaggg     1260

guaauggaaa aaauuauaug ggcaauuuau caaaaacacg uaguggauua acauguucaa     1320

ugugggauaa aaauauggaa gauuuacauc gacacauuuu cugggaaccc gaugcuagua     1380

aauuaaacaa aaacuauugu cgaaacccag augaugaugc acauggacca uggugcuaua     1440

cagguaaccc acuuauacca ugggacuauu guccuauauc aagaugugaa ggcgauacaa     1500

caccuacuau agucaauuua gaucauccug uaaucaguug cgcuaaaaca aaacaauuaa     1560

gaguuguaaa cggaauucca acacaaacaa caguaggaug gaugguauca cucaaauacc     1620

gaaauaaaca cauaugcgga gguucuuuaa uaaaagaaag cuggguauua accgcaagac     1680

aaugcuuccc ggcaagaaau aaagauuuaa aagauuauga agcaugguua ggaauacacg     1740

auguacacga aaggggagaa gaaaaaagaa aacaaauacu aaauauauca caauuaguau     1800

acggcccaga agggagcgau cuaguucuuc uaaaauuagc cagaccagca auauuagaua     1860

auuuuguauc uacuaucgau cuaccaucau auggauguac aauaccugag aaaacaacau     1920

guucaauaua uggaugggga uauacuggau uaauaaacgc cgauggacuu cuuagaguag     1980

cacacuuaua uauaauggga aacgaaaaau gcucacaaca ucaucaagga aaaguuacac     2040

uaaacgaauc agaacuaugu gcuggcgcag aaaaaaucgg aucaggccca ugcgaaggug     2100

auuacggcgg accacuuaua ugugaacaac auaaaaugcg caugguauua ggagucauag     2160

uucccggucg gggcugugcg auaccaaaca gaccaggcau auuuguccgu guagccuacu     2220

augcaaaaug gauacauaaa guaauauuaa cauauaaauu auaaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5526
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt12)

<400>  5526
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaggag acccaaaaaa accaagagga aaaaugucaa      120

gcuacgcauu cuucguacaa acaugcagag aagaacacaa aaaaaaacac ccagacgcaa      180

gcguaaacuu cagcgaauuc agcaaaaaau gcucagaaag guggaaaaca augagcgcaa      240

aagagaaagg aaaauucgaa gacauggcaa aagcagacaa agcaagauac gaaagagaaa      300

ugaaaacaua cauaccacca aaaggagaaa caaaaaaaaa auuuaaagac ccaaacgcac      360

caaaaagacc accaucagca uucuuccuau ucugcaguga auacagacca aaaauaaaag      420

gagaacaccc aggacuaagc auaggagacg uagcaaaaaa auuaggagaa auguggaaca      480

acacagcagc agacgacaaa caaccauacg aaaaaaaagc agcaaaauua aaagaaaaau      540

acgaaaagga cauagcagca uaucgagcaa aaggaaaacc agacgcagca aaaaaaggag      600

uaguaaaagc agaaaaaagc aaaaaaaaaa aagaagaaga agaagacgaa gaagacgaag      660

aagacgaaga agaagaagaa gacgaagaag acgaagacga agaagaagac gacgacgacg      720

aauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5527
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt12)

<400>  5527
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuac uaucaugggu acacuggaca cuagcauuac      120

uacuauacuu acaccacgca aaauggucac aagcagcacc aacaacagaa ggagaacaaa      180

aaucacacga aguaauaaaa uucauggacg uauaccaacg aucauacugc agaccaauag      240

aaacacuagu agacauauuc caagaauacc cagacgaaau agaauacaua uucaaaccau      300

caugcguacc auuaaugaga ugcgcaggau gcugcaacga cgaagcauua gaaugcguac      360

caacaucaga aucaaacaua acaaugcaaa uaaugagaau aaaaccacac caaucacaac      420

acauaggaga aaugucauuc cuacaacauu caagaugcga augcagacca aaaaaagaca      480

gaacaaaacc agaaaaaaaa ucaguaagag gaaaaggaaa aggacaaaaa agaaaaagaa      540

aaaaaucaag auucaaauca uggucaguac acugcgaacc augcucagaa cgaagaaaac      600

acuuauuugu acaagaccca caaacaugca aaugcucaug caaaaacaca gacucaagau      660

gcaaagcaag acaacuagaa cuaaaugaaa gaacaugcag augugacaaa ccaagacgau      720

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5528
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21(L126R,P199G,A208E) 
       (opt13)

<400>  5528
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucagacg aaacaggauu ugaacacuca ggacuauggg      120

uaucaguacu agcaggauua uuacuaggag ccugccaagc acacccaaua ccagacucau      180

caccauuauu acaauucgga ggacaaguua gacaaagaua ucuauauaca gaugacgcac      240

aacaaacaga agcacacuua gaaauaagag aagacggaac aguaggagga gcagcagacc      300

aaucaccaga aucccuacua caauuaaaag cacuaaaacc aggaguaaua caaauauuag      360

gaguaaaaac aucaagauuc cuaugccaaa gaccagacgg agcacuauac ggcucacuac      420

acuuugaccc agaagcaugc ucauucagag aaagacuacu agaagacgga uauaauguau      480

aucaaucaga agcacacgga cuaccuuuac auuuaccagg aaacaaauca ccacacagag      540

acccagcacc aagaggccca gcacgcuuuu uaccauuacc aggacuacca ccagcauuac      600

cagaaccacc aggaauacua gcaccacaac caccagaugu uggaagcuca gacccacuau      660

caaugguagg aggaucacaa ggaagaucac caucauauga aucauaagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5529
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001276387.1__MmHGF (opt13)

<400>  5529
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auguggggaa caaaacuuuu accuguucua uuauuacaac      120

acguccuguu acacuuauua uuacuacaug uagccauacc uuacgcagaa ggacaaaaga      180

aacgaagaaa cacacuucau gaauuuaaga aauccgcaaa aacaacauua acaaaagaag      240

auccauuauu aaaaauaaaa acaaagaaag uuaauucagc agaugaaugu gcaaauagau      300

guauaagaaa cagaggauuu accuuuacau guaaagcauu uguauucgac aaaucaagga      360

aacgauguua cugguaucca uucaauagua ugaguucugg aguaaagaaa ggauucgguc      420

augaguucga ccuauaugaa aauaaagacu auauuagaaa uuguauaauc ggcaaaggug      480

ggucuuauaa aggcacuguu aguauaacaa aaucaggaau aaaaugucaa ccauggaaua      540

gcaugauacc acacgaacac ucauuucucc caucuucaua caggggcaaa gaccuacaag      600

aaaauuauug uagaaaccca aggggagaag aaggaggccc augguguuuu acaucgaauc      660

cugaaguacg auaugaagua ugugacaucc cccaaugcag ugaaguagaa uguaugacuu      720

guaaugguga aucauaccga ggaccuaugg accauacaga aucaggaaaa acuugccaac      780

gaugggauca acaaaccccu caucgacaca aauuuuuacc agaacguuac ccagauaaag      840

gauuugacga uaauuacugu agaaauccag acgguaaacc ucgacccugg uguuacacuc      900

uugauccaga uacaccaugg gaauauugcg caauaaaaac uugcgcacau ucugcaguaa      960

augaaacaga cguuccaaug gaaacuaccg aauguauaca aggccaagga gaaggcuaua     1020

gagguacauc aaauacaaua uggaauggca uacccugcca aaggugggac ucucaauauc     1080

cacauaaaca ugauauaaca ccagaaaacu uuaaauguaa agauuuaaga gaaaauuacu     1140

guagaaaucc ggauggagca gaaucucccu gguguuucac uaccgauccu aacauaagag     1200

uaggauauug uagccaaaua ccuaaaugug auguuagcuc aggucaagac ugcuacagag     1260

guaauggcaa aaauuacaug gggaaucuca guaaaacacg uaguggacuc acauguucaa     1320

ugugggauaa aaauauggaa gaccugcaca gacauauauu cugggaaccu gaugcuucaa     1380

aauuaaauaa aaauuauugc agaaauccag augaugacgc ucacggacca ugguguuaca     1440

cugguaaucc auuaauacca ugggauuauu guccaauauc aagaugcgaa ggugauacaa     1500

cuccaacaau aguaaaucua gaucauccag uaauauccug ugcaaaaaca aaacaacuaa     1560

gaguaguaaa cggaauacca acacaaacaa caguaggaug gaugguuagu uuaaaauaca     1620

gaaauaaaca uauaugugga ggauccuuaa uaaaagaauc auggguauua acugcaagac     1680

aauguuuccc agcaaggaac aaagauuuaa aagauuacga agcauggcua ggaauacaug     1740

auguucacga aagaggagaa gaaaaacgua aacaaauuuu gaacauuuca caacuuguau     1800

acggcccaga aggaucugau uuaguauuau uaaaguuagc aagaccagca auucucgaua     1860

auuucguauc aacgauagau cuccccaguu acggcuguac gauaccagaa aagacaacau     1920

gcaguauaua cggaugggga uauacaggac uaaucaacgc agauggacuu uuaagaguag     1980

cccacuuaua uauaaugggu aacgaaaaau guucacaaca ucaucaagga aaaguaacac     2040

uaaaugaaag cgaauuaugu gcaggcgcag agaaaauagg aagcggaccu ugugaaggcg     2100

auuacggugg accacuaaua ugugaacaac auaaaaugag aaugguauua ggaguaauag     2160

uuccaggacg uggaugugcc auaccaaacc gaccaggaau auuuguuagg guagccuacu     2220

acgcaaaaug gauucacaaa guaauauuaa cauauaaacu auaaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5530
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt13)

<400>  5530
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaggag acccaaaaaa accgagagga aaaaugagca      120

gcuacgcauu uuucguacaa acaugcagag aagaacacaa aaaaaaacac ccagacgcaa      180

gcguaaacuu uagcgaauuu ucaaaaaaau gcucagaaag auggaaaaca augagcgcaa      240

aagaaaaagg aaaauucgaa gacauggcga aagcagacaa agcaagauau gaaagagaaa      300

ugaaaacaua cauaccacca aaaggagaaa ccaaaaaaaa auuuaaagac ccaaacgcac      360

caaaaagacc accaagcgca uucuuucuau ucugcaguga auacagacca aaaauaaaag      420

gagaacaccc aggauuaagc auaggagacg uagcaaaaaa acuaggagaa auguggaaca      480

acacagcagc agacgacaaa caaccauacg aaaaaaaagc agcaaaacua aaagaaaaau      540

acgaaaaaga cauagcagca uauagagcaa aaggaaaacc agacgcagca aaaaaaggag      600

uaguaaaagc agaaaaaagc aaaaaaaaaa aagaagaaga agaagacgaa gaagacgaag      660

aagacgaaga agaagaagaa gacgaagaag acgaagacga agaagaagac gacgacgacg      720

aauaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5531
<211>  921
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Mus musculus__NP_001273985.1__MmVEGFA (opt13)

<400>  5531
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuac uaucaugggu acacuggaca cuagcacuac      120

uacuauacuu acaccacgca aaauggaguc aagcagcacc aacaacagaa ggagaacaaa      180

aaagccacga aguaauaaaa uucauggacg uauaucaacg aucauacugc agaccaauag      240

aaacacuagu agauaucuuc caagaauacc cagacgaaau agaauacaua uucaaaccau      300

caugcguacc auuaaugaga ugcgcaggau gcugcaacga cgaagcacua gaaugcguac      360

caacaucaga aucaaacaua acaaugcaaa uaaugagaau aaaaccccac caaagccaac      420

acauaggaga aaugucauuc cuacaacacu caagaugcga augcagaccc aaaaaagacc      480

gaacaaaacc agaaaaaaaa ucaguaagag gaaaaggaaa aggacaaaaa agaaaacgaa      540

aaaaaucacg auucaaauca uggucaguac acugcgaacc augcucugaa agaagaaaac      600

accuauucgu acaagaccca caaacaugua aaugcagcug caaaaacaca gacucaagau      660

gcaaagcaag acaacuagaa uuaaacgaaa gaacaugcag augcgacaaa ccacgaagau      720

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      780

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      900

cuuuucagag ccaccagaau u                                                921


<210>  5532
<211>  2398
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design6 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt1) R6258

<400>  5532
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccugcug cuccagcacg      120

uccugcugca ccuccugcug cucccgaucg ccauccccua cgcggagggc cagcgcaagc      180

ggcgcaacac cauccacgag uucaagaaga gcgccaagac gacccugauc aagaucgacc      240

ccgcccugaa gaucaagacc aagaagguga acaccgccga ccagugcgcc aaccggugca      300

cgcgcaacaa ggggcucccc uucaccugca aggcguucgu guucgacaag gcccggaagc      360

agugccugug guucccguuc aacuccauga gcuccggcgu caagaaggag uucgggcacg      420

aguucgaccu guacgagaac aaggacuaca uccgcaacug caucaucggc aaggggcgga      480

gcuacaaggg caccgugucc aucaccaaga gcggcaucaa gugccagccc ugguccagca      540

ugauccccca cgagcacucc uuccucccca gcuccuaccg cgggaaggac cugcaggaga      600

acuacugccg gaacccgcgc ggcgaggagg gcgggcccug gugcuucacg agcaaccccg      660

aggugcggua cgaggucugc gacauccccc agugcuccga gguggagugc augaccugca      720

acggggagag cuaccgcggc cugauggacc acaccgaguc cggcaagauc ugccagcggu      780

gggaccacca gaccccgcac cgccacaagu uccuccccga gcgguacccc gacaaggggu      840

ucgacgacaa cuacugccgc aaccccgacg gccagccgcg gcccuggugc uacacgcugg      900

acccccacac ccgcugggag uacugcgcca ucaagaccug cgccgacaac accaugaacg      960

acacggacgu gccccuggag accaccgagu gcauccaggg gcagggcgag ggcuaccggg     1020

ggaccgucaa cacgaucugg aacggcaucc cgugccagcg cugggacagc caguaccccc     1080

acgagcacga caugaccccc gagaacuuca agugcaagga ccuccgggag aacuacugcc     1140

gcaaccccga cggguccgag agcccguggu gcuucaccac cgaccccaac auccgcgugg     1200

gcuacugcuc ccagaucccc aacugcgaca ugagccacgg gcaggacugc uaccggggca     1260

acggcaagaa cuacaugggg aaccugagcc agacgcgcuc cggccugacc ugcagcaugu     1320

gggacaagaa cauggaggac cuccaccggc acaucuucug ggagcccgac gcguccaagc     1380

ugaacgagaa cuacugccgc aacccggacg acgacgccca cgggcccugg ugcuacaccg     1440

gcaacccccu gaucccgugg gacuacugcc ccaucagccg gugcgagggg gacaccacgc     1500

ccaccaucgu gaaccucgac caccccguca ucuccugcgc caagaccaag cagcugcgcg     1560

uggugaacgg caucccgacc cggacgaaca ucggcuggau ggucagccug cgcuaccgga     1620

acaagcacau cugcgggggc ucccucauca aggagagcug ggugcugacc gcccgccagu     1680

gcuuccccuc ccgggaccug aaggacuacg aggccuggcu cgggauccac gacgugcacg     1740

gccgcgggga cgagaagugc aagcaggucc ugaacgugag ccagcuggug uacggccccg     1800

agggcuccga ccucguccug augaagcugg cgcggcccgc cgugcucgac gacuucguga     1860

gcaccaucga ccugccgaac uacgggugca ccauccccga gaagacgucc ugcagcgucu     1920

acggcugggg guacaccggc cugaucaacu acgacggccu ccugcgcgug gcccaccugu     1980

acaucauggg gaacgagaag ugcucccagc accaccgggg caaggucacc cucaacgaga     2040

gcgagaucug cgccggggcc gagaagaucg gcuccgggcc cugcgagggc gacuacggcg     2100

ggccccuggu gugcgagcag cacaagaugc gcauggugcu gggcgucauc gugccggggc     2160

ggggcugcgc gauccccaac cgccccggga ucuucgugcg ggucgccuac uacgccaagu     2220

ggauccacaa gaucauccug accuacaagg ugccccagag cugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa       2398


<210>  5533
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design7 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt1) R6259

<400>  5533
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccugcug cuccagcacg      120

uccugcugca ccuccugcug cucccgaucg ccauccccua cgcggagggc cagcgcaagc      180

ggcgcaacac cauccacgag uucaagaaga gcgccaagac gacccugauc aagaucgacc      240

ccgcccugaa gaucaagacc aagaagguga acaccgccga ccagugcgcc aaccggugca      300

cgcgcaacaa ggggcucccc uucaccugca aggcguucgu guucgacaag gcccggaagc      360

agugccugug guucccguuc aacuccauga gcuccggcgu caagaaggag uucgggcacg      420

aguucgaccu guacgagaac aaggacuaca uccgcaacug caucaucggc aaggggcgga      480

gcuacaaggg caccgugucc aucaccaaga gcggcaucaa gugccagccc ugguccagca      540

ugauccccca cgagcacucc uuccucccca gcuccuaccg cgggaaggac cugcaggaga      600

acuacugccg gaacccgcgc ggcgaggagg gcgggcccug gugcuucacg agcaaccccg      660

aggugcggua cgaggucugc gacauccccc agugcuccga gguggagugc augaccugca      720

acggggagag cuaccgcggc cugauggacc acaccgaguc cggcaagauc ugccagcggu      780

gggaccacca gaccccgcac cgccacaagu uccuccccga gcgguacccc gacaaggggu      840

ucgacgacaa cuacugccgc aaccccgacg gccagccgcg gcccuggugc uacacgcugg      900

acccccacac ccgcugggag uacugcgcca ucaagaccug cgccgacaac accaugaacg      960

acacggacgu gccccuggag accaccgagu gcauccaggg gcagggcgag ggcuaccggg     1020

ggaccgucaa cacgaucugg aacggcaucc cgugccagcg cugggacagc caguaccccc     1080

acgagcacga caugaccccc gagaacuuca agugcaagga ccuccgggag aacuacugcc     1140

gcaaccccga cggguccgag agcccguggu gcuucaccac cgaccccaac auccgcgugg     1200

gcuacugcuc ccagaucccc aacugcgaca ugagccacgg gcaggacugc uaccggggca     1260

acggcaagaa cuacaugggg aaccugagcc agacgcgcuc cggccugacc ugcagcaugu     1320

gggacaagaa cauggaggac cuccaccggc acaucuucug ggagcccgac gcguccaagc     1380

ugaacgagaa cuacugccgc aacccggacg acgacgccca cgggcccugg ugcuacaccg     1440

gcaacccccu gaucccgugg gacuacugcc ccaucagccg gugcgagggg gacaccacgc     1500

ccaccaucgu gaaccucgac caccccguca ucuccugcgc caagaccaag cagcugcgcg     1560

uggugaacgg caucccgacc cggacgaaca ucggcuggau ggucagccug cgcuaccgga     1620

acaagcacau cugcgggggc ucccucauca aggagagcug ggugcugacc gcccgccagu     1680

gcuuccccuc ccgggaccug aaggacuacg aggccuggcu cgggauccac gacgugcacg     1740

gccgcgggga cgagaagugc aagcaggucc ugaacgugag ccagcuggug uacggccccg     1800

agggcuccga ccucguccug augaagcugg cgcggcccgc cgugcucgac gacuucguga     1860

gcaccaucga ccugccgaac uacgggugca ccauccccga gaagacgucc ugcagcgucu     1920

acggcugggg guacaccggc cugaucaacu acgacggccu ccugcgcgug gcccaccugu     1980

acaucauggg gaacgagaag ugcucccagc accaccgggg caaggucacc cucaacgaga     2040

gcgagaucug cgccggggcc gagaagaucg gcuccgggcc cugcgagggc gacuacggcg     2100

ggccccuggu gugcgagcag cacaagaugc gcauggugcu gggcgucauc gugccggggc     2160

ggggcugcgc gauccccaac cgccccggga ucuucgugcg ggucgccuac uacgccaagu     2220

ggauccacaa gaucauccug accuacaagg ugccccagag cugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucucaaag     2340

gcucuuuuca gagccaccaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aa                                              2422


<210>  5534
<211>  2411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design8 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt1) R6260

<400>  5534
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccugcug cuccagcacg      120

uccugcugca ccuccugcug cucccgaucg ccauccccua cgcggagggc cagcgcaagc      180

ggcgcaacac cauccacgag uucaagaaga gcgccaagac gacccugauc aagaucgacc      240

ccgcccugaa gaucaagacc aagaagguga acaccgccga ccagugcgcc aaccggugca      300

cgcgcaacaa ggggcucccc uucaccugca aggcguucgu guucgacaag gcccggaagc      360

agugccugug guucccguuc aacuccauga gcuccggcgu caagaaggag uucgggcacg      420

aguucgaccu guacgagaac aaggacuaca uccgcaacug caucaucggc aaggggcgga      480

gcuacaaggg caccgugucc aucaccaaga gcggcaucaa gugccagccc ugguccagca      540

ugauccccca cgagcacucc uuccucccca gcuccuaccg cgggaaggac cugcaggaga      600

acuacugccg gaacccgcgc ggcgaggagg gcgggcccug gugcuucacg agcaaccccg      660

aggugcggua cgaggucugc gacauccccc agugcuccga gguggagugc augaccugca      720

acggggagag cuaccgcggc cugauggacc acaccgaguc cggcaagauc ugccagcggu      780

gggaccacca gaccccgcac cgccacaagu uccuccccga gcgguacccc gacaaggggu      840

ucgacgacaa cuacugccgc aaccccgacg gccagccgcg gcccuggugc uacacgcugg      900

acccccacac ccgcugggag uacugcgcca ucaagaccug cgccgacaac accaugaacg      960

acacggacgu gccccuggag accaccgagu gcauccaggg gcagggcgag ggcuaccggg     1020

ggaccgucaa cacgaucugg aacggcaucc cgugccagcg cugggacagc caguaccccc     1080

acgagcacga caugaccccc gagaacuuca agugcaagga ccuccgggag aacuacugcc     1140

gcaaccccga cggguccgag agcccguggu gcuucaccac cgaccccaac auccgcgugg     1200

gcuacugcuc ccagaucccc aacugcgaca ugagccacgg gcaggacugc uaccggggca     1260

acggcaagaa cuacaugggg aaccugagcc agacgcgcuc cggccugacc ugcagcaugu     1320

gggacaagaa cauggaggac cuccaccggc acaucuucug ggagcccgac gcguccaagc     1380

ugaacgagaa cuacugccgc aacccggacg acgacgccca cgggcccugg ugcuacaccg     1440

gcaacccccu gaucccgugg gacuacugcc ccaucagccg gugcgagggg gacaccacgc     1500

ccaccaucgu gaaccucgac caccccguca ucuccugcgc caagaccaag cagcugcgcg     1560

uggugaacgg caucccgacc cggacgaaca ucggcuggau ggucagccug cgcuaccgga     1620

acaagcacau cugcgggggc ucccucauca aggagagcug ggugcugacc gcccgccagu     1680

gcuuccccuc ccgggaccug aaggacuacg aggccuggcu cgggauccac gacgugcacg     1740

gccgcgggga cgagaagugc aagcaggucc ugaacgugag ccagcuggug uacggccccg     1800

agggcuccga ccucguccug augaagcugg cgcggcccgc cgugcucgac gacuucguga     1860

gcaccaucga ccugccgaac uacgggugca ccauccccga gaagacgucc ugcagcgucu     1920

acggcugggg guacaccggc cugaucaacu acgacggccu ccugcgcgug gcccaccugu     1980

acaucauggg gaacgagaag ugcucccagc accaccgggg caaggucacc cucaacgaga     2040

gcgagaucug cgccggggcc gagaagaucg gcuccgggcc cugcgagggc gacuacggcg     2100

ggccccuggu gugcgagcag cacaagaugc gcauggugcu gggcgucauc gugccggggc     2160

ggggcugcgc gauccccaac cgccccggga ucuucgugcg ggucgccuac uacgccaagu     2220

ggauccacaa gaucauccug accuacaagg ugccccagag cugaggacua guguccaccu     2280

gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga ucagcgcuuu     2340

acagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa a                                                          2411


<210>  5535
<211>  2435
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design9 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt1) R6261

<400>  5535
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccugcug cuccagcacg      120

uccugcugca ccuccugcug cucccgaucg ccauccccua cgcggagggc cagcgcaagc      180

ggcgcaacac cauccacgag uucaagaaga gcgccaagac gacccugauc aagaucgacc      240

ccgcccugaa gaucaagacc aagaagguga acaccgccga ccagugcgcc aaccggugca      300

cgcgcaacaa ggggcucccc uucaccugca aggcguucgu guucgacaag gcccggaagc      360

agugccugug guucccguuc aacuccauga gcuccggcgu caagaaggag uucgggcacg      420

aguucgaccu guacgagaac aaggacuaca uccgcaacug caucaucggc aaggggcgga      480

gcuacaaggg caccgugucc aucaccaaga gcggcaucaa gugccagccc ugguccagca      540

ugauccccca cgagcacucc uuccucccca gcuccuaccg cgggaaggac cugcaggaga      600

acuacugccg gaacccgcgc ggcgaggagg gcgggcccug gugcuucacg agcaaccccg      660

aggugcggua cgaggucugc gacauccccc agugcuccga gguggagugc augaccugca      720

acggggagag cuaccgcggc cugauggacc acaccgaguc cggcaagauc ugccagcggu      780

gggaccacca gaccccgcac cgccacaagu uccuccccga gcgguacccc gacaaggggu      840

ucgacgacaa cuacugccgc aaccccgacg gccagccgcg gcccuggugc uacacgcugg      900

acccccacac ccgcugggag uacugcgcca ucaagaccug cgccgacaac accaugaacg      960

acacggacgu gccccuggag accaccgagu gcauccaggg gcagggcgag ggcuaccggg     1020

ggaccgucaa cacgaucugg aacggcaucc cgugccagcg cugggacagc caguaccccc     1080

acgagcacga caugaccccc gagaacuuca agugcaagga ccuccgggag aacuacugcc     1140

gcaaccccga cggguccgag agcccguggu gcuucaccac cgaccccaac auccgcgugg     1200

gcuacugcuc ccagaucccc aacugcgaca ugagccacgg gcaggacugc uaccggggca     1260

acggcaagaa cuacaugggg aaccugagcc agacgcgcuc cggccugacc ugcagcaugu     1320

gggacaagaa cauggaggac cuccaccggc acaucuucug ggagcccgac gcguccaagc     1380

ugaacgagaa cuacugccgc aacccggacg acgacgccca cgggcccugg ugcuacaccg     1440

gcaacccccu gaucccgugg gacuacugcc ccaucagccg gugcgagggg gacaccacgc     1500

ccaccaucgu gaaccucgac caccccguca ucuccugcgc caagaccaag cagcugcgcg     1560

uggugaacgg caucccgacc cggacgaaca ucggcuggau ggucagccug cgcuaccgga     1620

acaagcacau cugcgggggc ucccucauca aggagagcug ggugcugacc gcccgccagu     1680

gcuuccccuc ccgggaccug aaggacuacg aggccuggcu cgggauccac gacgugcacg     1740

gccgcgggga cgagaagugc aagcaggucc ugaacgugag ccagcuggug uacggccccg     1800

agggcuccga ccucguccug augaagcugg cgcggcccgc cgugcucgac gacuucguga     1860

gcaccaucga ccugccgaac uacgggugca ccauccccga gaagacgucc ugcagcgucu     1920

acggcugggg guacaccggc cugaucaacu acgacggccu ccugcgcgug gcccaccugu     1980

acaucauggg gaacgagaag ugcucccagc accaccgggg caaggucacc cucaacgaga     2040

gcgagaucug cgccggggcc gagaagaucg gcuccgggcc cugcgagggc gacuacggcg     2100

ggccccuggu gugcgagcag cacaagaugc gcauggugcu gggcgucauc gugccggggc     2160

ggggcugcgc gauccccaac cgccccggga ucuucgugcg ggucgccuac uacgccaagu     2220

ggauccacaa gaucauccug accuacaagg ugccccagag cugaggacua guguccaccu     2280

gucccuccug ggcugcugga uugucucguu uuccugccaa auaaacagga ucagcgcuuu     2340

acagaucuca aaggcucuuu ucagagccac caaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaa                                2435


<210>  5536
<211>  2474
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design10 comprising derived and/or modified sequence
       from Homo sapiens__NP_000592.3__HsHGF (opt1) R6262

<400>  5536
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccugcug cuccagcacg      120

uccugcugca ccuccugcug cucccgaucg ccauccccua cgcggagggc cagcgcaagc      180

ggcgcaacac cauccacgag uucaagaaga gcgccaagac gacccugauc aagaucgacc      240

ccgcccugaa gaucaagacc aagaagguga acaccgccga ccagugcgcc aaccggugca      300

cgcgcaacaa ggggcucccc uucaccugca aggcguucgu guucgacaag gcccggaagc      360

agugccugug guucccguuc aacuccauga gcuccggcgu caagaaggag uucgggcacg      420

aguucgaccu guacgagaac aaggacuaca uccgcaacug caucaucggc aaggggcgga      480

gcuacaaggg caccgugucc aucaccaaga gcggcaucaa gugccagccc ugguccagca      540

ugauccccca cgagcacucc uuccucccca gcuccuaccg cgggaaggac cugcaggaga      600

acuacugccg gaacccgcgc ggcgaggagg gcgggcccug gugcuucacg agcaaccccg      660

aggugcggua cgaggucugc gacauccccc agugcuccga gguggagugc augaccugca      720

acggggagag cuaccgcggc cugauggacc acaccgaguc cggcaagauc ugccagcggu      780

gggaccacca gaccccgcac cgccacaagu uccuccccga gcgguacccc gacaaggggu      840

ucgacgacaa cuacugccgc aaccccgacg gccagccgcg gcccuggugc uacacgcugg      900

acccccacac ccgcugggag uacugcgcca ucaagaccug cgccgacaac accaugaacg      960

acacggacgu gccccuggag accaccgagu gcauccaggg gcagggcgag ggcuaccggg     1020

ggaccgucaa cacgaucugg aacggcaucc cgugccagcg cugggacagc caguaccccc     1080

acgagcacga caugaccccc gagaacuuca agugcaagga ccuccgggag aacuacugcc     1140

gcaaccccga cggguccgag agcccguggu gcuucaccac cgaccccaac auccgcgugg     1200

gcuacugcuc ccagaucccc aacugcgaca ugagccacgg gcaggacugc uaccggggca     1260

acggcaagaa cuacaugggg aaccugagcc agacgcgcuc cggccugacc ugcagcaugu     1320

gggacaagaa cauggaggac cuccaccggc acaucuucug ggagcccgac gcguccaagc     1380

ugaacgagaa cuacugccgc aacccggacg acgacgccca cgggcccugg ugcuacaccg     1440

gcaacccccu gaucccgugg gacuacugcc ccaucagccg gugcgagggg gacaccacgc     1500

ccaccaucgu gaaccucgac caccccguca ucuccugcgc caagaccaag cagcugcgcg     1560

uggugaacgg caucccgacc cggacgaaca ucggcuggau ggucagccug cgcuaccgga     1620

acaagcacau cugcgggggc ucccucauca aggagagcug ggugcugacc gcccgccagu     1680

gcuuccccuc ccgggaccug aaggacuacg aggccuggcu cgggauccac gacgugcacg     1740

gccgcgggga cgagaagugc aagcaggucc ugaacgugag ccagcuggug uacggccccg     1800

agggcuccga ccucguccug augaagcugg cgcggcccgc cgugcucgac gacuucguga     1860

gcaccaucga ccugccgaac uacgggugca ccauccccga gaagacgucc ugcagcgucu     1920

acggcugggg guacaccggc cugaucaacu acgacggccu ccugcgcgug gcccaccugu     1980

acaucauggg gaacgagaag ugcucccagc accaccgggg caaggucacc cucaacgaga     2040

gcgagaucug cgccggggcc gagaagaucg gcuccgggcc cugcgagggc gacuacggcg     2100

ggccccuggu gugcgagcag cacaagaugc gcauggugcu gggcgucauc gugccggggc     2160

ggggcugcgc gauccccaac cgccccggga ucuucgugcg ggucgccuac uacgccaagu     2220

ggauccacaa gaucauccug accuacaagg ugccccagag cugaggacua guggaagcau     2280

uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu uagaaggcua     2340

ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau     2400

cuaaaagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaa                                                       2474


<210>  5537
<211>  2498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design11 comprising derived and/or modified sequence
       from Homo sapiens__NP_000592.3__HsHGF (opt1) R6263

<400>  5537
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccugcug cuccagcacg      120

uccugcugca ccuccugcug cucccgaucg ccauccccua cgcggagggc cagcgcaagc      180

ggcgcaacac cauccacgag uucaagaaga gcgccaagac gacccugauc aagaucgacc      240

ccgcccugaa gaucaagacc aagaagguga acaccgccga ccagugcgcc aaccggugca      300

cgcgcaacaa ggggcucccc uucaccugca aggcguucgu guucgacaag gcccggaagc      360

agugccugug guucccguuc aacuccauga gcuccggcgu caagaaggag uucgggcacg      420

aguucgaccu guacgagaac aaggacuaca uccgcaacug caucaucggc aaggggcgga      480

gcuacaaggg caccgugucc aucaccaaga gcggcaucaa gugccagccc ugguccagca      540

ugauccccca cgagcacucc uuccucccca gcuccuaccg cgggaaggac cugcaggaga      600

acuacugccg gaacccgcgc ggcgaggagg gcgggcccug gugcuucacg agcaaccccg      660

aggugcggua cgaggucugc gacauccccc agugcuccga gguggagugc augaccugca      720

acggggagag cuaccgcggc cugauggacc acaccgaguc cggcaagauc ugccagcggu      780

gggaccacca gaccccgcac cgccacaagu uccuccccga gcgguacccc gacaaggggu      840

ucgacgacaa cuacugccgc aaccccgacg gccagccgcg gcccuggugc uacacgcugg      900

acccccacac ccgcugggag uacugcgcca ucaagaccug cgccgacaac accaugaacg      960

acacggacgu gccccuggag accaccgagu gcauccaggg gcagggcgag ggcuaccggg     1020

ggaccgucaa cacgaucugg aacggcaucc cgugccagcg cugggacagc caguaccccc     1080

acgagcacga caugaccccc gagaacuuca agugcaagga ccuccgggag aacuacugcc     1140

gcaaccccga cggguccgag agcccguggu gcuucaccac cgaccccaac auccgcgugg     1200

gcuacugcuc ccagaucccc aacugcgaca ugagccacgg gcaggacugc uaccggggca     1260

acggcaagaa cuacaugggg aaccugagcc agacgcgcuc cggccugacc ugcagcaugu     1320

gggacaagaa cauggaggac cuccaccggc acaucuucug ggagcccgac gcguccaagc     1380

ugaacgagaa cuacugccgc aacccggacg acgacgccca cgggcccugg ugcuacaccg     1440

gcaacccccu gaucccgugg gacuacugcc ccaucagccg gugcgagggg gacaccacgc     1500

ccaccaucgu gaaccucgac caccccguca ucuccugcgc caagaccaag cagcugcgcg     1560

uggugaacgg caucccgacc cggacgaaca ucggcuggau ggucagccug cgcuaccgga     1620

acaagcacau cugcgggggc ucccucauca aggagagcug ggugcugacc gcccgccagu     1680

gcuuccccuc ccgggaccug aaggacuacg aggccuggcu cgggauccac gacgugcacg     1740

gccgcgggga cgagaagugc aagcaggucc ugaacgugag ccagcuggug uacggccccg     1800

agggcuccga ccucguccug augaagcugg cgcggcccgc cgugcucgac gacuucguga     1860

gcaccaucga ccugccgaac uacgggugca ccauccccga gaagacgucc ugcagcgucu     1920

acggcugggg guacaccggc cugaucaacu acgacggccu ccugcgcgug gcccaccugu     1980

acaucauggg gaacgagaag ugcucccagc accaccgggg caaggucacc cucaacgaga     2040

gcgagaucug cgccggggcc gagaagaucg gcuccgggcc cugcgagggc gacuacggcg     2100

ggccccuggu gugcgagcag cacaagaugc gcauggugcu gggcgucauc gugccggggc     2160

ggggcugcgc gauccccaac cgccccggga ucuucgugcg ggucgccuac uacgccaagu     2220

ggauccacaa gaucauccug accuacaagg ugccccagag cugaggacua guggaagcau     2280

uuuccuggcu gauuaaaaga aauuacucag cuauggucau cuguuccugu uagaaggcua     2340

ugcagcauau uauauacuau gcgcauguua ugaaaugcau aauaaaaaau uuuaaaaaau     2400

cuaaaagauc ucaaaggcuc uuuucagagc caccaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa                             2498


<210>  5538
<211>  849
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design12 comprising derived and/or modified sequence
       from Mus musculus__NP_001273985.1__MmVEGFA (opt1) R888/R889

<400>  5538
gggagaaagc uuaccaugaa cuuccugcuc agcugggugc acuggacccu ggcccugcuc       60

cuguaccugc accacgcgaa guggucgcag gccgccccga cgaccgaggg cgagcagaag      120

agccacgagg ucaucaaguu cauggacgug uaccagcgga gcuacugccg ccccaucgag      180

acccucgugg acaucuucca ggaguacccg gacgagaucg aguacaucuu caagccgucg      240

ugcguccccc ugaugcggug cgcggggugc ugcaacgacg aggcccugga gugcgugccg      300

acgagcgaga gcaacaucac caugcagauc augcggauca agccgcacca gucgcagcac      360

aucggcgaga ugagcuuccu ccagcacagc cgcugcgagu gccggcccaa gaaggaccgg      420

accaagccgg agaagaaguc ggugcgcggc aaggggaagg gccagaagcg gaagcggaag      480

aagagccgcu ucaagagcug gucgguccac ugcgagccgu gcagcgagcg gcggaagcac      540

cuguucgugc aggaccccca gacgugcaag ugcagcugca agaacaccga cucgcgcugc      600

aaggcccggc agcuggagcu caacgagcgg accugccgcu gcgacaagcc gcggcgguga      660

ccacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      720

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaua uucccccccc cccccccccc cccccccccc ccucuagaca      840

auuggaauu                                                              849


<210>  5539
<211>  630
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_061986.1__HsFGF21

<400>  5539
auggacuccg acgaaaccgg cuucgaacac ucaggccucu gggucuccgu acuagccggc       60

cuccuccucg gcgccugcca agcccacccc auccccgacu ccucaccccu ccuacaauuc      120

ggcggccaag uccgccaacg cuaccuauac accgacgacg cccaacaaac cgaagcccac      180

cucgaaaucc gcgaagacgg caccgucggc ggcgccgccg accaaucccc cgaaucccua      240

cuacaacuca aagcccucaa accuggaguc auccaaauac ucggcgucaa aaccucccgc      300

uuccucugcc aacgccccga cggagcccuc uacggcuccc uccacuucga cccagaagcc      360

ugcucuuucc gagaacuccu cuuagaagac ggcuacaacg ucuaccaauc ugaagcccac      420

ggccuccccc uucaccuccc cggaaacaaa ucaccccacc gcgaccccgc accccgcggc      480

ccagccagau uccucccccu ccccggccuc ccaccagccc uccccgaacc acccggcauc      540

cucgcacccc aaccacccga cgucggcucc uccgaccccc ucucaauggu cggccccucc      600

caaggccgcu cccccucaua cgccucauga                                       630


<210>  5540
<211>  1410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_002412.1__HsMMP1

<400>  5540
augcauucgu ucccgccguu auuauuauua uuauuuuggg gggucgucag ccauucguuu       60

ccggccaccu uggagaccca ggaacaggac gucgaucucg ugcaaaagua uuuagagaag      120

uauuauaauu uaaaaaacga cggccgccag gucgagaaaa gacgcaacuc ggggccgguc      180

gucgagaagc ucaaacagau gcaagaguuu uucggcuuaa aggucaccgg caagccggac      240

gccgagacgu uaaaagucau gaaacaaccg cgcugcgggg ucccggacgu cgcccaauuc      300

guguugaccg aaggcaaucc gaggugggaa cagacccacu uaacguaucg caucgagaac      360

uauaccccgg accucccgcg cgccgacguc gaucacgcga ucgaaaaggc guuucaguug      420

uggucgaacg ugaccccguu aaccuuuacg aaagugagcg aagggcaggc cgauauaaug      480

aucagcuucg ugcgcgggga ccacagagau aauagcccgu ucgacgggcc gggggggaac      540

uuggcccacg ccuuccagcc ggggccgggg aucgggggcg acgcccacuu cgacgaggac      600

gagcgcugga cgaauaacuu ucgcgaauau aaucuccaca gggucgccgc ccacgaguug      660

gggcacagcu ugggguugag ucacagcacc gacauaggcg cccucaugua uccgucguau      720

acguuuucgg gggacgucca auuggcccaa gacgauaucg acgggauaca ggcgaucuac      780

gggaggaguc agaacccggu gcaaccgaua gggccgcaga cgccgaaggc cugcgauucg      840

aaauugacgu ucgacgccau caccaccauc agaggggagg ucauguuuuu caaggaucgc      900

uuuuauauga ggaccaaccc guuuuauccc gaggucgaau ugaacuuuau cagcgucuuu      960

uggccgcagu uaccgaacgg cuuggaggcc gccuaugagu ucgcggaucg cgacgaggug     1020

agauucuuua agggcaacaa auauugggcc guccaagggc aaaacgucuu gcauggguau     1080

ccgaaagaua uauauucgag uuucggguuu ccgcgcaccg ucaaacacau agacgccgcc     1140

uugagcgaag agaauaccgg gaagacguau uuuuucgucg ccaauaagua uuggcgcuac     1200

gacgaguaca agaggagcau ggacccgggg uacccgaaga ugaucgccca cgauuucccg     1260

gggaucgggc auaaggucga cgccgucuuu augaaggacg gguucuuuua cuuuuuccac     1320

gggacccgcc aguauaaguu cgacccgaag accaaacgca uccucaccuu gcaaaaggcc     1380

aacucguggu uuaauugucg caagaacuga                                      1410


<210>  5541
<211>  3066
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Clostridium 
       histolyticum__BAA34542.1__ColH

<400>  5541
augaagcgca agugccugag caagcggcuc augcuggcca ucaccauggc caccaucuuc       60

acggugaacu ccacccugcc caucuacgcg gccgucgaca agaacaacgc caccgccgcc      120

gugcagaacg agagcaagcg cuacaccgug uccuaccuca agacgcugaa cuacuacgac      180

cuggucgacc uccuggugaa gaccgagauc gagaaccugc cggaccucuu ccaguacagc      240

uccgacgcga aggaguucua cggcaacaag acccggauga gcuucaucau ggacgagauc      300

gggcgccggg cgccccagua caccgagauc gaccacaagg gcauccccac gcugguggag      360

gucgugcgcg ccggguucua ccugggcuuc cacaacaagg agcucaacga gaucaacaag      420

cgguccuuca aggagcgcgu gauccccagc auccuggcca uccagaagaa cccgaacuuc      480

aagcugggga ccgaggucca ggacaagauc guguccgcca ccggccuccu ggccggcaac      540

gagaccgccc cgcccgaggu ggucaacaac uucacgccca uccugcagga cugcaucaag      600

aacaucgacc gguacgcccu cgacgaccuc aagagcaagg cccuguucaa cgugcucgcg      660

gccccgaccu acgacaucac cgaguaccug cgcgccacca aggagaagcc cgagaacacg      720

cccugguacg ggaagaucga cggcuucauc aacgagcuga agaagcucgc ccuguacggg      780

aagaucaacg acaacaacuc cuggaucauc gacaacggca ucuaccacau cgcgccccug      840

gggaagcucc acagcaacaa caagaucggc aucgagaccc ugaccgaggu gaugaagguc      900

uacccguacc uguccaugca gcaccuccag agcgccgacc agaucaagcg gcacuacgac      960

uccaaggacg ccgagggcaa caagaucccc cuggacaagu ucaagaagga ggggaaggag     1020

aaguacugcc ccaagaccua cacguucgac gacggcaagg ugaucaucaa ggccggggcc     1080

cgcguggagg aggagaaggu caagcggcug uacugggcca gcaaggaggu gaacucccag     1140

uucuuccgcg uguacggcau cgacaagccc cucgaggagg gcaacccgga cgacauccug     1200

accaugguca ucuacaacag ccccgaggag uacaagcuga acuccgugcu cuacggguac     1260

gacaccaaca acggcgggau guacaucgag cccgagggca ccuucuucac guacgagcgg     1320

gaggcgcagg agagcaccua cacccuggag gagcuguucc gccacgagua cacccacuac     1380

cuccaggggc gguacgccgu gcccggccag uggggccgca cgaagcugua cgacaacgac     1440

cggcugaccu gguacgagga gggcggggcc gagcuguucg ccgggagcac ccgcaccucc     1500

ggcauccugc cgcgcaagag caucgucucc aacauccaca acacgacccg gaacaaccgc     1560

uacaagcuga gcgacaccgu gcacuccaag uacggggcca gcuucgaguu cuacaacuac     1620

gcgugcaugu ucauggacua cauguacaac aaggacaugg gcauccucaa caagcugaac     1680

gaccuggcca agaacaacga cgucgacggc uacgacaacu acauccggga ccucuccagc     1740

aacuacgccc ugaacgacaa guaccaggac cacaugcagg agcgcaucga caacuacgag     1800

aaccugaccg ugcccuucgu ggccgacgac uaccuggucc ggcacgcgua caagaacccc     1860

aacgagaucu acuccgagau cagcgaggug gccaagcuca aggacgccaa guccgaggug     1920

aagaaguccc aguacuucag cacguucacc cugcgcggga gcuacaccgg cggggccucc     1980

aagggcaagc uggaggacca gaaggccaug aacaaguuca ucgacgacag ccucaagaag     2040

cuggacaccu acuccuggag cggguacaag acccugacgg cguacuucac caacuacaag     2100

gucgacucca gcaaccgggu gaccuacgac guggucuucc acggcuaccu ccccaacgag     2160

ggcgacagca agaacucccu gccguacggg aagaucaacg gcaccuacaa ggggacggag     2220

aaggagaaga ucaaguucag cuccgagggc agcuucgacc ccgacggcaa gaucgugucc     2280

uacgaguggg acuucgggga cggcaacaag agcaacgagg agaaccccga gcacuccuac     2340

gacaaggugg ggaccuacac cgucaagcug aaggugaccg acgacaaggg cgagagcucc     2400

gugagcacga ccaccgccga gaucaaggac cucuccgaga acaagcugcc cgucaucuac     2460

augcacgugc ccaagagcgg ggcccugaac cagaaggugg ucuucuacgg caagggcacc     2520

uacgaccccg acggguccau cgccggcuac cagugggacu ucggggacgg cagcgacuuc     2580

uccagcgagc agaaccccuc ccacguguac acgaagaagg gggaguacac cgugacccuc     2640

cgcgucaugg acagcagcgg ccagaugucc gagaagacca ugaagaucaa gaucacggac     2700

ccgguguacc ccaucggcac cgagaaggag cccaacaaca gcaaggagac cgccuccggg     2760

cccaucgugc cgggcauccc cgucagcggg accaucgaga acacguccga ccaggacuac     2820

uucuacuucg acgugaucac ccccggcgag gugaagaucg acaucaacaa gcugggguac     2880

ggcggcgcga ccugggucgu guacgacgag aacaacaacg ccgugagcua cgccaccgac     2940

gacgggcaga accuguccgg caaguucaag gccgacaagc ccgggcggua cuacauccac     3000

cucuacaugu ucaacggcag cuacaugccg uaccgcauca acaucgaggg guccgucggc     3060

cgguga                                                                3066


<210>  5542
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  5542
auguggguca cgaaguuguu accggcguua uuauuacaac acguguuguu acacuuguug       60

uuauugccga uagcgauacc guaugccgaa gggcagcgca agcgccgcaa uaccauccac      120

gaguuuaaga agagugccaa aaccacguug auaaagaucg acccggccuu aaaaaucaag      180

acgaaaaagg ucaacaccgc cgaucagugc gccaaccgcu gcacccgcaa caagggguug      240

ccguuuaccu guaaagccuu cgucuucgac aaggcccgca agcaauguuu gugguuuccg      300

uuuaacucga ugagcucggg ggucaagaag gaguucgggc acgaguucga uuuguaugag      360

aauaaggauu auauccgcaa uuguauaauc gggaaaggga ggucguauaa agggaccguc      420

agcauaacca aaucggggau aaaaugccaa ccguggucga guaugauccc gcaugagcau      480

ucguuccucc cgagcucgua cagagggaag gauuugcaag agaauuauug caggaacccg      540

aggggcgagg agggcgggcc guggugcuuu accucgaacc cggaagucag guaugaggug      600

ugcgauaucc cgcaaugcag cgaggucgag uguaugacgu guaacggcga aucguacagg      660

ggguugaugg accacaccga gagcgggaaa aucugccaaa ggugggacca ccaaaccccg      720

cauagacaua aauuucuccc ggagcgcuau ccggauaaag gguucgacga caacuacugu      780

aggaacccgg acgggcaacc ccgcccgugg uguuauaccu uggauccgca uacgaggugg      840

gaauauugcg ccaucaaaac cugugccgau aacaccauga acgauaccga cgucccgcuc      900

gagaccaccg aguguauaca ggggcagggg gagggguauc gcgggaccgu gaacacgauc      960

uggaacggga ucccgugcca aaggugggac agccaauauc cgcaugaaca cgauaugacc     1020

ccggagaacu uuaaauguaa agauuugagg gagaacuauu guaggaaccc ggacggcagc     1080

gagagcccgu ggugcuucac gaccgacccg aauauaaggg ucggguauug uagucagauc     1140

ccgaauugcg acaugagcca cgggcaagac ugcuauaggg gcaacgggaa aaacuacaug     1200

gggaaucuca gucagacccg cagcggguug accugcagca ugugggauaa aaauauggag     1260

gaucuccaca ggcacauauu uugggagccg gacgccucga aauuaaacga aaacuauugu     1320

aggaacccgg acgacgacgc ccacgggccg ugguguuaua ccgggaaccc guugaucccg     1380

ugggacuauu guccgaucag uaggugcgag ggggacacga ccccgaccau cgugaaccuc     1440

gaucacccgg ucaucagcug cgcgaagacc aagcagcuca gggucgucaa cggcaucccg     1500

accaggacca auaucgggug gauggucucg cuccgcuauc gcaacaagca cauauguggg     1560

gggagccuca ucaaagaauc gugggucuug accgccaggc aaugcuuucc gagcagggau     1620

cucaaggacu acgaggccug guuggggauc cacgacgugc augggcgcgg ggacgaaaag     1680

uguaagcaag ucuugaacgu cagucaauua gucuacgggc cggaggggag cgacuuaguc     1740

cucaugaaau uggcgcgccc ggccguguua gacgacuucg ucucgaccau cgaccucccg     1800

aauuacgggu guaccauccc ggagaaaacg ucguguucgg ucuaugggug gggguauacc     1860

gggcucauaa auuacgacgg guugcucagg gucgcccacu uguauaucau ggggaacgaa     1920

aaguguucgc aacaccacag gggcaaaguc accuuaaacg aaagcgagau cugcgccggc     1980

gccgagaaaa ucgggagcgg gccgugcgaa ggcgacuaug gggggccguu ggucugcgaa     2040

cagcacaaaa ugcgcauggu cuugggggug aucgucccgg ggagggggug cgcgaucccg     2100

aacaggccgg ggaucuucgu gagggucgcc uacuacgcca aguggaucca uaagaucauc     2160

cucaccuaua aagucccgca aagcuga                                         2187


<210>  5543
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001133.1__HsAMELX

<400>  5543
auggguacgu ggauacucuu cgcgugcuug uuaggugcgg cguucgcgau gccguuaccg       60

ccgcacccag gccacccggg auacaucaac uucucguacg aggucuuaac gccgcucaag      120

ugguaccaga guauccgacc uccuuacccc ucguacggau acgagccgau gggggguugg      180

uuacaccacc agauaauacc aguauugagu cagcaacacc cgccaacgca cacuuuacag      240

ccgcaccacc acauccccgu aguccccgcg cagcaaccgg ucaucccgca acagccgaug      300

augccgguac ccgggcagca cucgaugaca ccuauccagc accaccaacc gaacuugccg      360

ccgccggcgc agcaacccua ccagccacag ccgguccagc cucaacccca ccagccuaug      420

cagccucagc cgccgguaca cccgaugcag ccguuaccac cgcagccccc guuaccgccc      480

auguucccga ugcaaccccu cccgccgaug uuaccggacu uaacguuaga ggcguggccu      540

ucgacggaca agacgaagcg cgaggagguu gacuga                                576


<210>  5544
<211>  135
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001133.1__HsAMELX-TRAP

<400>  5544
augccguugc cgccgcaucc gggucacccg ggguauauaa acuucucgua ugaggucuug       60

acgccgcuca agugguacca aucgauucgc ccgccuuacc cgaguuaugg guacgagccg      120

augggggggu gguga                                                       135


<210>  5545
<211>  579
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001134.1__HsAMELY

<400>  5545
auggguacau ggauauuauu cgcgugcuug gucggugcug cauucgcaau gccauuaccu       60

ccccacccag gccacccggg guacauuaau uucucguacg agguauuaac gccgcuuaaa      120

ugguaccaga guaugaucag gccgccguac ucgucguacg gauacgaacc cauggggggu      180

ugguuacauc accagauaau accgguaguc ucgcagcagc acccguuaac gcacacguug      240

caaucgcacc accacauacc gguaguaccg gcgcagcaac cucgcguuag gcagcaggcg      300

uuaaugccgg uaccggggca gcagucgaug acaccgaccc agcaccacca gccgaacuua      360

ccauuacccg cucaacagcc auuccagccg caacccgucc agccgcaacc ccaucagccg      420

augcaaccgc aaccgccggu acagccgaug cagccguugu uaccgcagcc gccguugcca      480

cccauguucc cguuacgccc uuuaccuccg aucuuaccgg acuuacacuu agaggcaugg      540

ccggcgacgg acaagacgaa gcaggaggag guagacuga                             579


<210>  5546
<211>  138
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001134.1__HsAMELY-TRAP

<400>  5546
augccguugc cgccgcaccc gggccauccg ggguacauaa auuuuucgua cgaagucuug       60

acgccgcuca aaugguauca aucgaugauc cgcccgccgu auagcaguua cggguaugaa      120

ccgauggggg ggugguga                                                    138


<210>  5547
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  5547
augcccggag ucgcgcgauu gccauugcuc uuagguuugu uauuauuacc acgcccgggg       60

aggccccucg acuuagcgga cuacacguac gacuuggcag aggaggacga cucugaaccu      120

uuaaacuaca aggacccgug caaggcugcc gcguucuuag gggacauagc guuggacgag      180

gaggacuuac gcgcuuucca aguccagcag gcgguugacu uaaggcgcca cacggcgcgg      240

aaaaguucga ucaaggcggc gguacccggg aacacaagua cgccgucgug ccaaaguaca      300

aacggacaac cacagcgcgg ggcgugcgga cgguggcgag ggaggucgag gaguaggcga      360

gcagccaccu cgcgucccga gcggguaugg ccggacggug uaauuccauu cguaauaggu      420

ggcaacuuca cgggaaguca gcgggcggua uuccgccagg cgaugcgaca cugggagaaa      480

cacacaugcg uuacguucuu ggagcgaacc gacgaggacu cguacauagu auuuacguac      540

cguccaugcg gcugcugcag uuacguaggg cgaaggggug gcgguccgca agcgaucucg      600

auagguaaga acugcgacaa guucgguauc guaguucacg aguuagguca cguuguaggu      660

uucuggcacg agcacacgcg accugaccgc gacaggcacg ucaguauagu ccgcgagaac      720

auacagccgg gacaggagua caacuucuua aaaauggagc cgcaagaggu ugagucguug      780

ggugagacgu acgacuucga cucgauaaug cacuacgcgc gaaacacguu cucgcgcggg      840

auuuucuuag acacaauagu uccgaaauac gagguaaacg gcgucaagcc gccgauaggc      900

cagcggacuc gcuugucgaa gggugacaua gcgcaggcgc ggaaguugua uaagugcccg      960

gcgugcggug agacauuaca ggacucgacg ggaaacuuua guucgcccga guacccuaac     1020

ggcuacucgg cgcacaugca cugcgucugg cgaauaucgg uaacuccggg ggagaagauu     1080

auuuuaaauu ucacuucauu ggauuuauau aggucgcgau uauguuggua cgacuacgua     1140

gaaguaaggg acggguuuug gcguaaggcc ccuuugcgug ggcgauucug cggaucgaag     1200

uuaccggagc cgauaguaag uacggacucg cguuuauggg uagaguuccg aaguucgagu     1260

aacuggguag guaaggguuu cuucgccguu uacgaggcaa uaugcggugg ggacguaaag     1320

aaggacuacg gucauauaca gucuccgaau uacccggacg acuacaggcc uaguaaggua     1380

uguauauggc gcauccaagu cucggaggga uuccauguug gguugacguu ucagaguuuc     1440

gagauagaga ggcacgacuc gugcgcguac gauuacuuag agguaaggga cggacauucg     1500

gagucgagua cuuuaauagg acgauacugc gguuacgaga agccggacga cauaaagucg     1560

acuucgucgc gauugugguu aaaguucguu ucggacggaa guauaaacaa ggcagguuuc     1620

gcgguuaacu ucuuuaagga gguagacgag ugcucgcgac cgaaccgagg cgguugcgag     1680

caacgaugcu uaaacacguu gggaucuuac aaaugcucuu gcgacccggg uuacgaguug     1740

gcgccggaua agaggcgaug cgaggcggca ugcggggguu ucuuaacaaa guugaacggu     1800

ucgauaacau cgcccgggug gccgaaggag uacccgccga acaagaacug cauauggcaa     1860

uuagucgcgc cgacacaaua ccggauuucg uuacaguucg acuucuucga gacggagggu     1920

aacgacgucu guaaguacga cuucgucgag guccgaucgg guuugacugc ggacucaaag     1980

uuacacggua aguucugcgg cucggagaag ccggagguaa uuacaucgca guacaacaac     2040

augcgagucg aguucaaguc ggacaacacg guaaguaaga agggguucaa ggcacacuuc     2100

uucucggaua aggacgagug uucgaaagac aacggggguu gccaacagga cugcguaaac     2160

accuucgguu cguacgagug ucagugccga ucggguuucg uauuacacga caacaagcac     2220

gacugcaagg aggcaggaug cgaccauaag gucacgucga cuucggggac gauaacgucg     2280

ccgaacuggc cggacaagua cccgucgaag aaggagugca ccugggcgau cucgucaacu     2340

ccgggucauc gaguuaaguu gacguucaug gagauggaua uugagucgca gcccgagugc     2400

gcguacgacc acuuagaggu auucgacggg cgugacgcga aagcaccggu auuaggaagg     2460

uucugcgguu cgaagaaacc cgaaccgguu uuggcgacgg gaagucguau guucuuacgg     2520

uucuacucgg acaauagugu acaacguaag ggguuccaag caucgcaugc gacggagugc     2580

gguggucagg uccgagcgga cguuaaaacg aaagacuuau acucgcacgc gcaguucggg     2640

gacaauaacu acccgggcgg gguugacugc gaguggguua uagucgcaga ggagggguac     2700

gguguagagu uaguauucca gacuuucgag gucgaggagg agacggacug cgguuacgac     2760

uacauggagu uauucgacgg uuacgacucg acggcgccac gauuagguag guacugcggg     2820

ucgggaccgc cggaggaggu auacucagcc ggugacagug uauuagucaa guuucacucu     2880

gacgacacga uaacgaagaa gggcuuccac uuacguuaca cgaguacgaa guuccaggac     2940

acguuacacu cucgaaagug a                                               2961


<210>  5548
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  5548
auggucgcgg gcacgaggug uuuguuggca cucuuauugc cgcaaguauu guuagggggg       60

gccgcggggu ugguccccga guuagggagg cgcaaguucg ccgccgcaag cagcgggagg      120

ccgagcaguc agccgagcga cgagguauua ucggaguucg agcucagauu auugucgaug      180

uucggguuaa aacaacgccc gacgccgucg cgcgacgcgg ucgucccgcc guauauguug      240

gacuuauaua ggcgccacag cgggcagccc gggagcccgg cgccggacca cagacucgag      300

cgcgcggcgu cgagggcgaa cacggucagg ucguuccacc augaagaaag ccucgaagaa      360

uugccggaaa caucgggcaa aacgacgaga cgcuucuucu uuaaucucuc gagcauaccg      420

accgaggagu uuauaacgag cgccgaguug caagucuuca gggaacagau gcaagaugcg      480

cucgggaaca auucgucguu ccaucacagg auaaauauau augaaauaau uaaaccggcc      540

acggcgaaca gcaaauuccc ggucacgcgc uugcucgaca cgcgccucgu caaucagaau      600

gcgucgcgcu gggaaucguu ugauguaacg ccggcgguca ugagauggac cgcccagggg      660

cacgcgaacc auggguucgu cgucgaaguc gcgcaccucg aggagaaaca agggguaagu      720

aagcgccaug uccgcauuuc gcgcagccuc caccaagaug aacacucgug gagccagauu      780

cgcccgcucu uggucacguu ugggcaugau gggaaaggcc auccguugca caaacgcgaa      840

aaaaggcaag cgaaacacaa acaaagaaaa agguugaaga guucguguaa gcgccacccg      900

cucuacgucg acuucucgga cgucgguugg aaugacugga uagucgcccc gccuggcuau      960

cacgcguuuu auugccacgg ggaaugcccg uuuccguuag ccgaucauuu aaacaguacg     1020

aaucaugcga uaguccagac acucguaaac agcgucaaca gcaagauacc gaaagcgugc     1080

uguguaccca cggaauuguc ggcgauaagc auguuauauu uggacgagaa ugaaaagguc     1140

guccucaaaa auuaucagga cauggucguc gaggggugug gcuguaggug a              1191


<210>  5549
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  5549
augauaccgg gaaacaggau guuaauggua guauuguugu gccagguauu auuggguggu       60

gccucgcacg cgaguuugau cccggagacc gguaagaaga agguagcgga gauccagggc      120

cacgcggggg gccgacguag cggucagucg cacgaguuau ugcgagacuu cgaggccacg      180

cucuuacaga uguucggucu ucgccgaagg ccgcagccgu cuaagucggc cgucauaccc      240

gacuacaugc gagacuuaua ccgauuacag ucgggcgagg aggaggagga gcagauccac      300

aguacggggu uagaguaccc ggagcguccg gccucgcgag cgaacacggu ccgcucguuc      360

caccacgagg agcacuugga gaacauaccg ggcaccucgg agaacagugc guucagauuc      420

uuauucaacu uaucgaguau cccagagaac gaggugauau cuagugcgga guugcgcuua      480

uuccgugagc agguugacca agggccggac ugggagcgcg gcuuccaccg aaucaacauc      540

uacgagguga ugaagccgcc ggcggaggua guacccgguc acuuaaucac ucgucucuua      600

gacacgcgau uaguacacca caacguaacg aggugggaga cguucgacgu caguccggcg      660

guauugaggu ggacgcgcga gaagcagccc aacuacggau uagcgaucga ggucacgcac      720

cuacaccaga cccguacgca ccagggccag cacguccgaa uaucgcgauc gcuaccgcag      780

ggaucgggua acugggcgca auuaagaccg uuguuaguaa cguucggcca cgacgggcga      840

ggccacgcuu uaacgcgucg acgacgugcg aagcgcucgc cgaagcacca cucgcagcga      900

gcgcgaaaga agaacaagaa cugccgacgu cacagucuuu acguugacuu cucggacguc      960

ggauggaacg acuggauagu ugcgccgccg ggcuaccagg cguucuacug ccacggggac     1020

ugcccguucc cguuagccga ccacuuaaac aguaccaacc acgccaucgu ccagacgcuu     1080

guaaacucgg uaaacaguuc aauacccaag gcgugcugcg uacccacgga guuaagugcg     1140

aucucgaugu uauacuugga cgaguacgac aagguuguuu uaaagaacua ccaggagaug     1200

guuguggagg gcugcggaug ccguuga                                         1227


<210>  5550
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  5550
augcccggcu uaggcagacg cgcccaaugg uuauguuggu gguggggcuu auuauguucg       60

uguuguggcc cgccccccuu aagacccccg cucccggccg cggccgcggc ggcggcgggc      120

ggccaauuau uaggcgaugg gggcucgccg gggaggaccg aacaaccccc ccccagcccc      180

caaaguagua gcggguuuuu auauagaaga uugaaaaccc aagaaaaaag agaaaugcaa      240

aaagaaauac ucagcgucuu aggcuugccc cauagaccga gaccguuaca uggguugcag      300

caaccccaac cgcccgccuu gagacaacaa gaagaacaac aacaacaaca acaauuaccg      360

aggggggaac cgccgccggg cagguuaaaa agugccccgu uguuuauguu agacuuauau      420

aaugcguuaa gugcggauaa ugaugaagau ggcgccagcg aaggcgaacg ccaacaaagu      480

uggccgcaug aggccgcguc gagcagucaa aggagacaac ccccgcccgg ggcggcccau      540

cccuugaaua ggaaaucguu guuagcgccg gggagcgggu cggggggggc caguccguua      600

acgucggccc aagauucggc guuuuugaau gaugccgaua uggugauguc guucgucaau      660

uuagucgaau augauaaaga auuuaguccg aggcaaaggc aucauaagga auuuaaauuu      720

aaucucaguc aaaucccgga aggggaaguc gucaccgccg ccgaguuuag gauauauaaa      780

gauugcguca ugggcucguu caagaaucag accuucuuga uaucgaucua ccaggugcuc      840

caagaacacc aacaucgcga uagcgauuua uuccuccucg auacgagggu cgucugggcg      900

agcgaggagg ggugguuaga guucgauaua accgcgaccu cgaacuuaug ggucgucacc      960

ccgcaacaca auaugggcuu gcaauuaucg gucgucaccc gcgacggggu gcaugugcau     1020

ccgagggcgg ccggguuagu cgggcgcgau gggccguaug auaaacaacc guuuaugguc     1080

gccuuuuuua aggucucgga aguccauguc aggacgacgc gcagcgcgag uucgagaagg     1140

aggcagcaau cgaggaacag gagcacgcaa agucaagaug ucgccagagu gaguucggcc     1200

agcgacuaua auucgucgga gcucaagacc gcgugucgca aacacgaauu auacgucucg     1260

uuucaggauu uaggguggca agauuggaua aucgccccga aaggguacgc cgcgaacuau     1320

ugcgacgggg aguguaguuu uccguugaau gcccauauga acgccacgaa ucaugccauc     1380

guccaaacgc ucguccauuu gaugaauccg gaauacgugc cgaagcccug uugcgccccg     1440

accaaauuga acgcgauaag cgucuuguau uucgacgaua auaguaacgu gaucuuaaag     1500

aaguaucgca acauggucgu ccgcgccugc gggugucauu ga                        1542


<210>  5551
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  5551
augcacguaa gaucguuacg agcggcggcu ccgcacaguu ucguagcguu gugggccccg       60

uuauucuuau ugcgaucggc guuagcggac uucaguuuag acaacgaggu acacucgagu      120

uucauacacc gaagauugcg cucgcaggag aggcgcgaga ugcagcgaga gauauuaagu      180

auauuagggu ugccgcaccg acccaggccc cacuugcagg ggaagcacaa cucggcucca      240

auguucaugu uagacuuaua caacgcgaug gcgguagagg aggggggggg ucccgggggu      300

cagggcuuca guuaccccua caaggcggua uucucuacgc aggguccgcc guuagcgagu      360

uuacaggacu cgcacuucuu gacggacgcg gacaugguaa ugaguuucgu aaacuuagua      420

gagcacgaca aggaguucuu ccacccgcga uaccaccaca gggaguuccg auucgacuua      480

ucgaagauac ccgaggggga ggcgguaacg gcggcggagu ucaggauaua caaggacuac      540

auccgagaga gauucgacaa cgagacguuc cgaauaagug uauaccaggu auugcaggag      600

cacuuaggua gggagucgga cuuauucuug uuagacaguc gcacguuaug ggcgucggag      660

gaggguuggu uggucuucga cauaacggcg acgaguaacc acugggucgu aaaccccagg      720

cacaacuuag guuuacaguu gucgguagag acauuagacg gucagucgau aaacccgaag      780

uuagccgggu ugaucggucg acacggcccg cagaacaagc agccguucau gguagccuuc      840

uucaaggcga cggagguaca cuucaggagu auaaggucga cggguaguaa gcagcgaucg      900

cagaacagga guaagacacc aaagaaccag gaggcguuaa gaauggcgaa cguagcugag      960

aacucgaguu cggaccagag gcaggcgugc aagaagcacg aguuauacgu aaguuuccgc     1020

gacuuggggu ggcaggacug gauaauagcg ccggaggggu acgcagcgua cuacugcgag     1080

ggugagugcg cguuccccuu aaacucguac augaacgcga cgaaccacgc gauaguacag     1140

acguuaguac acuucaucaa cccggagaca guaccgaagc cgugcugcgc gccgacgcag     1200

uugaacgcga uaaguguauu auacuucgac gacucgagua acguaaucuu aaagaaguac     1260

aggaacaugg uaguacgagc gugcgguugc cacuga                               1296


<210>  5552
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  5552
augaaggcgu cggccgcguu acuaugcuua uuacuuaccg ccgcggcguu cucgccgcag       60

ggcuuagcgc aaccgguagg uauaaacacc aguacgacau gcugcuacag guucauaaac      120

aagaagaucc cgaagcagcg auuagagagu uaccgucgua cgacgagcuc ucacugcccg      180

cgugaggcgg ucauauucaa aacgaaguua gacaaggaga uaugcgcaga ccccacccag      240

aaguggguac aggacuucau gaagcacuua gacaagaaga cgcagacgcc uaaguuguga      300


<210>  5553
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  5553
auguuauuga ccuugauaau cuuacucccg gucgucagca aguucucguu cgucucguug       60

agcgcccccc aacauugguc gugcccggag gggaccuugg ccgggaacgg caacaguacc      120

ugcgucgggc cggccccguu ucucaucuuu agucacggga acucgauauu ccgcaucgau      180

accgagggga cgaacuacga acagcucguc gucgacgccg gggugagcgu cauaauggac      240

uuccacuaca acgaaaagcg cauauacugg gucgaccucg agcgccaguu gcuccagcgc      300

gucuucuuaa acggcagccg ccaggaacgc gucugcaaca ucgaaaagaa cgucagcggg      360

auggccauca acuggaucaa cgaggagguc aucuggagca accagcaaga ggggauaauc      420

accgucaccg acaugaaggg gaacaacagu cauaucuugc ucucggcccu caaguacccg      480

gccaacgucg ccgucgaccc ggucgagcgc uucaucuucu ggagcagcga agucgccggg      540

ucguuguacc gcgccgacuu ggacgggguc ggggucaaag ccuuacucga aaccagcgaa      600

aagaucaccg ccgucagccu cgacgucuug gacaaaagau uauucuggau ccaauauaau      660

cgcgaggggu cgaacagcuu gaucuguagu ugcgacuacg acggggggag cgugcauauc      720

ucgaagcacc cgacccaaca caaccucuuc gccaugaguu uguucgggga uaggauauuu      780

uacagcaccu ggaagaugaa aaccaucugg aucgcgaaua agcauaccgg gaaagauaug      840

guccgcauca auuugcacag cagcuucguc ccguuggggg aguuaaaggu cguccacccg      900

uuggcccagc cgaaagccga ggacgauacc ugggaaccgg aacaaaaguu guguaagcuc      960

cgcaagggga auuguucguc gaccgucugc ggccaggauu ugcaaagcca ucucuguaug     1020

ugcgccgaag gguaugcguu gucgagggau agaaaauauu gcgaggacgu caacgagugc     1080

gccuucugga accacgggug caccuugggc ugcaagaaua cgccggggag uuacuauugu     1140

accuguccgg ucggguucgu cuuauugccg gacggcaaga ggugccacca guuggucagu     1200

ugcccgagga acgucagcga guguucgcac gauugcgucu uaaccagcga ggggccgcuc     1260

ugcuuuugcc cggaggggag cgucuuggaa cgcgacggca agaccugcuc ggggugcagu     1320

agcccggaca acggggggug cucgcaauug ugugucccgu ugucgccggu caguugggag     1380

ugcgacuguu ucccgggcua cgauuugcag uuagacgaga agucgugcgc cgccagcggg     1440

ccgcagccgu uccucuuauu cgcgaacagc caggacauca ggcauaugca cuucgacggg     1500

accgauuacg ggaccuuauu gucgcaacaa auggggaugg ucuacgcguu ggaccacgau     1560

ccggucgaga acaaaaucua uuucgcgcac accgcguuaa aauggaucga acgcgccaac     1620

auggacggga gucaaaggga gcgcuugauc gaagaggggg ucgacguccc ggagggguug     1680

gccgucgauu ggaucgggag gcgcuuuuac uggaccgauc gcggcaagag cuuaaucggg     1740

cgcucggacc ucaacggcaa gaggaguaag aucauaacca aagaaaauau aagccagccg     1800

agggggaucg ccguccaccc gauggcgaaa cgccucuuuu ggaccgacac cggcaucaac     1860

ccgaggaucg agucgagcag uuugcagggg uuggggaggu uagucaucgc gucgagcgac     1920

uugauauggc cgucggggau caccaucgau uuucucaccg auaaacucua uuggugugac     1980

gcgaaacaaa gcgucaucga gauggcgaac uuagacggga gcaagaggag gcgcuugacg     2040

caaaacgacg ucgggcaucc guucgccguc gccgucuucg aagacuacgu cugguuuagc     2100

gacugggcca ugccgagcgu caugcgcguc aauaaacgca ccgggaagga ccgcgucagg     2160

uugcaggggu cgauguuaaa accgagcagc uuagucgucg uccacccgcu cgccaagccg     2220

ggggccgacc cgugucucua ccagaauggg gggugcgagc acaucuguaa gaaacgcuug     2280

gggaccgccu ggugcagcug cagggagggg uucaugaagg cgagcgacgg caagaccugc     2340

uuagccuuag acgggcacca auuacucgcc gggggggagg ucgacuugaa aaaucagguc     2400

accccgcucg auauacucag uaaaacccgc gucagcgagg acaauaucac cgagagccag     2460

cauauguugg ucgccgagau aauggucagc gaccaggacg auugcgcccc ggucgggugu     2520

ucgauguacg ccagaugcau cagcgaaggg gaagacgcga ccugccaaug ccucaagggg     2580

uucgccggcg acgggaaguu gugcagcgac aucgacgagu gcgaaauggg ggugccgguc     2640

uguccgccgg cgaguaguaa auguauaaau acggaggggg gguacgugug uagauguagc     2700

gagggguauc agggggacgg cauccauugc uuggacaucg acgaauguca guuaggcgaa     2760

cauucgugcg gggaaaacgc gucguguacc aacaccgaag ggggguacac guguaugugc     2820

gccgggaggu uaagcgagcc gggguuaauc uguccggaua gcaccccgcc gccgcauuug     2880

cgcgaggacg aucaucauua caguguccgc aacucggaua gcgagugccc guuaagucau     2940

gacggcuauu guuugcacga cggggucugu auguacaucg aggcccucga uaaauacgcc     3000

uguaauugcg ucgucgggua uauaggcgaa aggugccaau auagggauuu aaaauggugg     3060

gaguuaaggc augccgggca uggccaacaa caaaaaguga uagucgucgc cguguguguc     3120

gucgucuugg ugauguuauu guuguuaucg uuauggggcg cgcauuauua ucgcacccaa     3180

aaauuauuga gcaagaaucc gaaaaacccg uacgaagaaa gcucgcgcga cguccgcucg     3240

aggcgcccgg ccgauaccga agacggcaug aguagcuguc cgcagccgug guucgucguc     3300

aucaaggagc aucaggauuu gaaaaacggc gggcagccgg ucgccgggga agacgggcaa     3360

gccgccgacg gcagcaugca gccgaccagc uggcgccaag aaccgcaacu cugcgggaug     3420

gggaccgaac agggguguug gaucccgguc aguucggaca aagggaguug cccgcaaguc     3480

auggaaaggu cguuccacau gccgaguuac ggcacccaaa cguuggaggg cgggguggaa     3540

aaaccgcaca gcuuguugag cgccaauccg cucuggcagc agcgcgcguu agauccgccg     3600

caucagaugg aauuaaccca auga                                            3624


<210>  5554
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  5554
augacggccg gccgccgcau ggaaauguug ugcgcggggc gcgugccggc cuuauuauug       60

uguuuagggu uucacuuguu gcaagccgug uugucgacca ccgucauccc gagcugcaua      120

ccgggggaaa guucggacaa uuguaccgcc cucguccaaa ccgaggauaa cccgaggguc      180

gcccagguca gcaucaccaa augcucgagc gauaugaacg gguacugccu ccacgggcaa      240

uguauauacu uagucgauau gucgcagaau uauugucgcu gcgaggucgg guacaccggg      300

gugaggugcg agcauuuuuu ccucacggug caucagccgc ucucgaagga guacgucgcc      360

cucacgguca ucuugaucau ccucuucuug auaaccgugg uggggaguac cuacuacuuu      420

ugucgcuggu aucgcaacag gaagucgaag gagccgaaaa aagaguacga acgcgucacg      480

agcggcgacc cggaacuccc ccagguguga                                       510


<210>  5555
<211>  468
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_000791.1__HsFGF1

<400>  5555
auggcggagg gugagauaac gacguucacu gcguuaacgg agaaguucaa cuuaccgccg       60

gguaacuaca agaagcccaa guuguuauac ugcucgaacg gggggcacuu cuuacgaaua      120

uuaccagacg gcacgguaga cgguacccga gaccggucgg accagcacau ccaguuacaa      180

uuaucggcgg agaguguugg cgagguauac aucaagucga cugagacagg gcaguacuug      240

gcgauggaca cggacggguu auuguacggg agucaaacgc cgaacgagga gugcuuauuc      300

uuagagcgcu uggaggagaa ccacuacaac acguacaucu cgaagaagca cgcggagaag      360

aacugguucg uaggguuaaa gaagaacggu aguugcaagc gggggccacg cacgcacuac      420

ggucagaagg cgaucuuauu cuugccguua ccaguaucga gugacuga                   468


<210>  5556
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  5556
auggugggcg ucgggggcgg ggacguggag gacgugaccc cgcgcccggg cgggugccag       60

aucucgggcc ggggcgcccg cgggugcaac ggcauccccg gggccgcggc cugggaggcc      120

gcccugcccc ggcgccggcc ccgccggcac ccguccguca acccccgcuc gcgggccgcg      180

ggcucgcccc gcacccgggg gcgccggacg gaggagcgcc ccuccggcuc ccggcucggc      240

gaccgcgggc ggggccgcgc ccugcccggg ggccggcugg gcgggcgcgg ccgggggcgc      300

gcccccgagc gcgugggcgg gcggggccgc ggccggggga ccgccgcgcc ccgcgccgcc      360

cccgccgccc ggggcucgcg cccggggccc gcgggcacca uggccgccgg guccaucacc      420

acgcuccccg cccugcccga ggacggcggc ucgggggccu ucccgcccgg ccacuucaag      480

gaccccaagc ggcuguacug caagaacggg ggcuucuucc uccgcaucca ccccgacggg      540

cggguggacg gcguccgcga gaaguccgac ccgcacauca agcugcagcu gcaggcggag      600

gagcggggcg uggugucgau caaggggguc ugcgccaacc gcuaccucgc caugaaggag      660

gacggccggc ugcuggccuc caagugcgug accgacgagu gcuucuucuu cgagcgccuc      720

gagucgaaca acuacaacac cuaccggucc cgcaaguaca ccucguggua cguggccuua      780

aagcggacgg ggcaguacaa guuaggcucc aagaccggcc ccgggcagaa ggcgauccuc      840

uucuuaccca ugucggccaa guccuga                                          867


<210>  5557
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  5557
augcacaagu ggauauuaac guggauauug ccgacguuau uauacagguc gugcuuccac       60

auaauaugcu uggucgggac aauaaguuua gcgugcaacg acaugacgcc cgagcaaaug      120

gcgacgaacg uaaauugcuc gaguccggag agacacacga ggucguauga cuauauggag      180

gggggcgaca uaagagucag gagauuauuc ugcaggacac aaugguauuu gagaauagac      240

aagaggggca aagucaaggg gacgcaagag augaaaaaca acuauaacau aauggagaua      300

agaacgguag ccgucggcau agucgcgaua aaagggguag agagugaguu cuauuuagcg      360

augaacaagg aggggaaguu auaugcgaag aaggagugca acgaggacug caauuucaag      420

gaguugauau uagagaacca cuauaacacg uacgcgucgg ccaaguggac acacaacggc      480

ggggagaugu ucgucgcguu aaaccaaaag ggcauaccgg ucagggggaa gaagacgaag      540

aaagagcaaa agacggcgca cuucuugccg auggcgauaa cguga                      585


<210>  5558
<211>  627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001936.1__HsHBEGF

<400>  5558
augaaguugu uacccucagu uguacucaaa uuauucuuag cggccguauu aagugcucuu       60

gugaccggcg agucguugga gcguuugcgc cgcggucuug cagcgggcac gaguaacccg      120

gacccgccga cggucucgac cgaccaguua cucccucucg ggggcgggcg cgaccguaag      180

guucgggacc uccaggaggc ggacuuagac cuccuacgug uuacgcuuuc gucgaagccc      240

caggccuugg cgaccccuaa caaggaggag cacgguaagc guaagaagaa ggggaagggg      300

cuuggcaaga agcgugaccc gugcuugcga aaguacaagg acuucugcau acacggggag      360

ugcaaguacg ucaaggaguu acgagcgccg aguugcaucu gccacccggg cuaccacggg      420

gagcgaugcc acggcuuguc guuaccggua gagaaccguu uguacacuua cgaccacacu      480

accauacucg ccguagucgc gguugucuua ucgucgguau gcuuauuagu aauaguaggc      540

uuauuaaugu uccgauacca ccgacgcggg ggcuacgacg uagagaacga ggagaaggug      600

aagcuaggga ugacgaacuc gcacuga                                          627


<210>  5559
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  5559
auguggguca cgaaguuguu accggcguua uuauuacaac acguguuguu acacuuguug       60

uuauugccga uagcgauacc guaugccgaa gggcagcgca agcgccgcaa uaccauccac      120

gaguuuaaga agagugccaa aaccacguug auaaagaucg acccggccuu aaaaaucaag      180

acgaaaaagg ucaacaccgc cgaucagugc gccaaccgcu gcacccgcaa caagggguug      240

ccguuuaccu guaaagccuu cgucuucgac aaggcccgca agcaauguuu gugguuuccg      300

uuuaacucga ugagcucggg ggucaagaag gaguucgggc acgaguucga uuuguaugag      360

aauaaggauu auauccgcaa uuguauaauc gggaaaggga ggucguauaa agggaccguc      420

agcauaacca aaucggggau aaaaugccaa ccguggucga guaugauccc gcaugagcau      480

ucguuccucc cgagcucgua cagagggaag gauuugcaag agaauuauug caggaacccg      540

aggggcgagg agggcgggcc guggugcuuu accucgaacc cggaagucag guaugaggug      600

ugcgauaucc cgcaaugcag cgaggucgag uguaugacgu guaacggcga aucguacagg      660

ggguugaugg accacaccga gagcgggaaa aucugccaaa ggugggacca ccaaaccccg      720

cauagacaua aauuucuccc ggagcgcuau ccggauaaag gguucgacga caacuacugu      780

aggaacccgg acgggcaacc ccgcccgugg uguuauaccu uggauccgca uacgaggugg      840

gaauauugcg ccaucaaaac cugugccgau aacaccauga acgauaccga cgucccgcuc      900

gagaccaccg aguguauaca ggggcagggg gagggguauc gcgggaccgu gaacacgauc      960

uggaacggga ucccgugcca aaggugggac agccaauauc cgcaugaaca cgauaugacc     1020

ccggagaacu uuaaauguaa agauuugagg gagaacuauu guaggaaccc ggacggcagc     1080

gagagcccgu ggugcuucac gaccgacccg aauauaaggg ucggguauug uagucagauc     1140

ccgaauugcg acaugagcca cgggcaagac ugcuauaggg gcaacgggaa aaacuacaug     1200

gggaaucuca gucagacccg cagcggguug accugcagca ugugggauaa aaauauggag     1260

gaucuccaca ggcacauauu uugggagccg gacgccucga aauuaaacga aaacuauugu     1320

aggaacccgg acgacgacgc ccacgggccg ugguguuaua ccgggaaccc guugaucccg     1380

ugggacuauu guccgaucag uaggugcgag ggggacacga ccccgaccau cgugaaccuc     1440

gaucacccgg ucaucagcug cgcgaagacc aagcagcuca gggucgucaa cggcaucccg     1500

accaggacca auaucgggug gauggucucg cuccgcuauc gcaacaagca cauauguggg     1560

gggagccuca ucaaagaauc gugggucuug accgccaggc aaugcuuucc gagcagggau     1620

cucaaggacu acgaggccug guuggggauc cacgacgugc augggcgcgg ggacgaaaag     1680

uguaagcaag ucuugaacgu cagucaauua gucuacgggc cggaggggag cgacuuaguc     1740

cucaugaaau uggcgcgccc ggccguguua gacgacuucg ucucgaccau cgaccucccg     1800

aauuacgggu guaccauccc ggagaaaacg ucguguucgg ucuaugggug gggguauacc     1860

gggcucauaa auuacgacgg guugcucagg gucgcccacu uguauaucau ggggaacgaa     1920

aaguguucgc aacaccacag gggcaaaguc accuuaaacg aaagcgagau cugcgccggc     1980

gccgagaaaa ucgggagcgg gccgugcgaa ggcgacuaug gggggccguu ggucugcgaa     2040

cagcacaaaa ugcgcauggu cuugggggug aucgucccgg ggagggggug cgcgaucccg     2100

aacaggccgg ggaucuucgu gagggucgcc uacuacgcca aguggaucca uaagaucauc     2160

cucaccuaua aagucccgca aagcuga                                         2187


<210>  5560
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  5560
auggcgaagg cggcggcaau agggauagac uuagguacga cguacucgug cguuggugua       60

uuccagcacg guaagguaga gauaauagcg aacgaccagg guaaccggac gacgccgagu      120

uacgucgcgu ucaccgacac ggagcgcuug aucggggacg ccgcgaagaa ccagguagcu      180

uuaaacccac aaaacacggu uuucgacgca aagcgacuca uagggcgaaa guucggggac      240

cccgucguac aaucagacau gaagcacugg ccguuccagg ucauaaacga cggugacaag      300

ccgaaggucc agguaaguua caagggcgag acgaaggcgu ucuacccuga ggagaucuca      360

aguaugguau ugacgaagau gaaggagaua gcggaggcau acuuaggaua ccccgugacg      420

aacgccguaa ucacgguccc cgcguacuuc aacgacucuc agcggcaggc gacgaaggac      480

gcaggcguaa ucgcaggguu aaacguauug cgcaucauaa acgagccgac cgcggcggcg      540

auagcauacg gguuagaccg gaccgggaag ggugagcgaa acguauuaau cuucgacuug      600

ggugggggua cguucgacgu cucgauauua accaucgacg acggcauauu cgagguaaag      660

gcgaccgccg gggacacgca cuuaggcggg gaggacuucg acaaccgauu ggucaaccac      720

uucguagagg aguucaagcg aaagcacaag aaggacauau cgcagaacaa gcgugcggua      780

agaagguuac gaacggcgug cgagcgggcu aagcgcacgu uaaguucgag uacgcaggcg      840

ucguuggaga uagacaguuu auucgagggu auagacuucu acacuucgau aacgcgugca      900

cgauucgagg aguuaugcuc ggacuuauuc aggucgacgu uagagccggu agagaaggca      960

uuacgagacg cgaaguugga caaggcacag auacacgacu uaguauuagu aggugguucg     1020

acgcggauac cgaagguaca gaaguuguua caggacuucu ucaacggucg agacuuaaac     1080

aagucgauca acccggacga ggcgguagcg uacggggccg cgguacaggc cgcgauauug     1140

augggugaca agagugagaa cguacaggac uuauuauuau uagacguagc acccuuaucu     1200

uuggguuuag agaccgcggg uggggucaug acggcguuaa uaaagcgaaa cucgacgauc     1260

ccgacgaagc agacccagau cuucacuacg uacucggaca accagccggg uguauugauc     1320

cagguauacg agggugagcg agcgaugacc aaggacaaca acuuauuagg acguuucgag     1380

uugucgggua uaccgcccgc accucgaggg gucccgcaga ucgaggucac guucgacauc     1440

gacgcgaacg guaucuuaaa cguaacggcg accgacaaaa guacggggaa ggccaacaag     1500

aucacgauaa cgaacgacaa gggucgauua ucgaaggagg agauagagag gaugguccag     1560

gaggcagaga aguacaaggc cgaggacgag guccagagag agcgaguaag ugcgaagaac     1620

gcguuggagu cguacgcguu caacaugaag agugcggucg aggacgaggg uuuaaagggu     1680

aagaucucgg aggccgacaa gaagaagguc uuagacaagu gccaggaggu uauaucuugg     1740

uuagacgcga acacguuagc ggagaaggac gaguucgagc acaagcgcaa ggaguuagag     1800

cagguaugca acccgauaau aucggguuug uaccaggggg cgggcgggcc ggguccgggu     1860

gguuucggcg cgcagggacc gaaggguggu agugggucgg guccgacgau cgaggaggua     1920

gacuga                                                                1926


<210>  5561
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  5561
auggcgaagg cggcggcaau agggauagac uuagguacga cguacucgug cguuggugua       60

uuccagcacg guaagguaga gauaauagcg aacgaccagg guaaccggac gacgccgagu      120

uacgucgcgu ucaccgacac ggagcgcuug aucggggacg ccgcgaagaa ccagguagcu      180

uuaaacccac aaaacacggu uuucgacgca aagcgacuca uagggcgaaa guucggggac      240

cccgucguac aaucagacau gaagcacugg ccguuccagg ucauaaacga cggugacaag      300

ccgaaggucc agguaaguua caagggcgag acgaaggcgu ucuacccuga ggagaucuca      360

aguaugguau ugacgaagau gaaggagaua gcggaggcau acuuaggaua ccccgugacg      420

aacgccguaa ucacgguccc cgcguacuuc aacgacucuc agcggcaggc gacgaaggac      480

gcaggcguaa ucgcaggguu aaacguauug cgcaucauaa acgagccgac cgcggcggcg      540

auagcauacg gguuagaccg gaccgggaag ggugagcgaa acguauuaau cuucgacuug      600

ggugggggua cguucgacgu cucgauauua accaucgacg acggcauauu cgagguaaag      660

gcgaccgccg gggacacgca cuuaggcggg gaggacuucg acaaccgauu ggucaaccac      720

uucguagagg aguucaagcg aaagcacaag aaggacauau cgcagaacaa gcgugcggua      780

agaagguuac gaacggcgug cgagcgggcu aagcgcacgu uaaguucgag uacgcaggcg      840

ucguuggaga uagacaguuu auucgagggu auagacuucu acacuucgau aacgcgugca      900

cgauucgagg aguuaugcuc ggacuuauuc aggucgacgu uagagccggu agagaaggca      960

uuacgagacg cgaaguugga caaggcacag auacacgacu uaguauuagu aggugguucg     1020

acgcggauac cgaagguaca gaaguuguua caggacuucu ucaacggucg agacuuaaac     1080

aagucgauca acccggacga ggcgguagcg uacggggccg cgguacaggc cgcgauauug     1140

augggugaca agagugagaa cguacaggac uuauuauuau uagacguagc acccuuaucu     1200

uuggguuuag agaccgcggg uggggucaug acggcguuaa uaaagcgaaa cucgacgauc     1260

ccgacgaagc agacccagau cuucacuacg uacucggaca accagccggg uguauugauc     1320

cagguauacg agggugagcg agcgaugacc aaggacaaca acuuauuagg acguuucgag     1380

uugucgggua uaccgcccgc accucgaggg gucccgcaga ucgaggucac guucgacauc     1440

gacgcgaacg guaucuuaaa cguaacggcg accgacaaaa guacggggaa ggccaacaag     1500

aucacgauaa cgaacgacaa gggucgauua ucgaaggagg agauagagag gaugguccag     1560

gaggcagaga aguacaaggc cgaggacgag guccagagag agcgaguaag ugcgaagaac     1620

gcguuggagu cguacgcguu caacaugaag agugcggucg aggacgaggg uuuaaagggu     1680

aagaucucgg aggccgacaa gaagaagguc uuagacaagu gccaggaggu uauaucuugg     1740

uuagacgcga acacguuagc ggagaaggac gaguucgagc acaagcgcaa ggaguuagag     1800

cagguaugca acccgauaau aucggguuug uaccaggggg cgggcgggcc ggguccgggu     1860

gguuucggcg cgcagggacc gaaggguggu agugggucgg guccgacgau cgaggaggua     1920

gacuga                                                                1926


<210>  5562
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  5562
auggcgacgg cgaaggguau agcuauaggu auagacuuag gaacgacaua cucgugcgua       60

ggugucuucc agcacgggaa ggucgagauc auagcuaacg accaggggaa caggacaacg      120

ccgaguuacg ucgcguucac cgacacugag agauugaucg gugacgcggc gaagaaccag      180

gucgcgauga acccucaaaa cacgguauuc gacgcgaagc gguuaaucgg ucgcaaguuc      240

aacgacccgg ucguucaggc ggacaugaag uuauggccgu uccaaguaau aaacgagggc      300

ggaaagccga agguauuggu aucguacaag ggugagaaca aggcauucua cccggaagag      360

auaaguucga ugguuuuaac caaguuaaag gagacagcgg aggcguucuu aggucauccg      420

guaacuaacg cgguaaucac gguacccgcu uacuucaacg acagucagcg gcaggcgacg      480

aaggacgcgg gggucauagc ggguuuaaac guauuacgca uaauaaacga gccaacggca      540

gcggcgauag cguacggucu ugacaagggg ggacagggug agcggcacgu auuaaucuuc      600

gacuuaggug gcgguacauu cgacgucucg auauugacga ucgacgacgg uauauucgag      660

guaaaggcga cggcggguga cacgcacuua gguggugagg acuucgacaa cagauuagua      720

agucacuucg ucgaggaguu caagcggaag cacaagaagg acauaucgca aaacaagcgc      780

gcuguaagga gauugcggac ggccugcgag cgcgcgaagc ggacguuaag uucgucgacg      840

caggcgaacc ucgagauaga cucguuguac gaggguauag acuuuuacac gaguaucacg      900

cgagcgagau ucgaggaguu augcgccgac uuauuccgcg ggacauugga gcccguugag      960

aaggcguuaa gggacgcgaa gauggacaag gcgaagaucc acgacauagu auuagucggu     1020

gguucgaccc gaauaccgaa gguacagcgg uuauuacaag acuacuucaa cggucgcgac     1080

uugaacaagu cgauaaaccc ggacgaggcg guagcguacg gggcggcagu ccaggcggcg     1140

auauuaaugg gggacaaguc ggagaagguc caagacuuau uauuguugga cguugcgccg     1200

uuaaguuuag guuuagagac ugcgggcggu guaaugacgg cguuaaucaa gcggaacucg     1260

acaauaccaa cgaagcagac gcaaauauuc acuacguaca gugacaacca gccgggugua     1320

uugauacagg uauacgaggg ugagcgggcg augacgaagg acaacaacuu auuaggucgu     1380

uucgacuuaa cugguauacc uccggcuccg cgggggguac cgcaaauaga ggucacguuc     1440

gacauagacg cgaacgggau cuuaaacgua acggcgaccg acaagucgac agguaagguu     1500

aacaagauaa cuauaacgaa cgacaagggu agauuaucga aggaggagau cgagaggaug     1560

gucuuggacg cggagaagua caaggcagag gacgagguac agagagaaaa gauagcggcg     1620

aagaacgcgu uagagaguua cgcguucaac augaagucgg uaguaucgga cgagggauua     1680

aaggguaaga ucucggagag ugacaagaac aagauauuag acaagugcaa cgaguuauua     1740

ucgugguugg agguuaacca guuagcggag aaggacgagu ucgaccauaa gaggaaggag     1800

uuagagcaaa ugugcaaccc gaucaucacg aaguuauacc agggggguug cacggguccg     1860

gcgugcggua cggguuacgu cccugggcga ccggcaacag guccgacgau agaggaggua     1920

gacuga                                                                1926


<210>  5563
<211>  1920
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_068814.2 __HsHSPA2

<400>  5563
augucggcca gggggccggc cauagggauc gauuugggga cgacguauag cugugucggg       60

gucuuucaac augggaaggu ggagaucaua gccaaugauc agggcaaucg cacgaccccg      120

aguuacgucg cguucaccga uacggagagg uugauagggg augccgcgaa aaaucaaguc      180

gccaugaauc cgaccaauac cauauuugau gccaaacgcu ugauagggag gaaauuugag      240

gaugccaccg ugcagucgga uaugaaacau uggccguuua gggucgucag ugaggggggg      300

aagccgaaag uacaggugga guauaagggg gaaaccaaaa cguucuuucc ggaggaaaua      360

agcucgaugg ucuugacgaa gaugaaggag aucgccgaag ccuacuuggg ggggaaagug      420

cauucggccg ucaucaccgu gccggccuau uucaaugauu cgcagcgcca ggccaccaag      480

gaugccggga cgaucaccgg guugaaugug uugaggauca uaaacgagcc gaccgccgcc      540

gccauagccu auggguugga uaaaaagggg ugugcggggg gggaaaagaa uguguugauc      600

uuugauuugg ggggcgggac cuuugaugug agcaucuuga cgaucgagga ugggauauuu      660

gaagugaagu cgaccgcggg ggauacccau uuggggggcg aggauuuuga uaauaggaug      720

gucucgcacu uggcggagga auuuaagcgc aaacauaaaa aggacaucgg gccgaauaag      780

agagccgucc gccgcuugcg cacggccugu gagagagcca agcgcacguu gucgagcucg      840

acccaggccu cgaucgagau agauaguuug uaugagggcg ucgauuuuua uacgagcaua      900

accagagcga gguucgaaga guugaaugcg gacuuauuua gggggaccuu ggagccggug      960

gagaaggccu ugagggaugc caagcucgau aaggggcaga uccaggagau cguguuagug     1020

ggggggagua cgaggauacc gaagauacag aaguuguugc aggauuuuuu uaauggcaag     1080

gaguugaaua agagcaucaa uccggacgag gccguggcgu auggggccgc cguccaggcc     1140

gccaucuuga uaggcgauaa gucggaaaau gugcaggauu uguuguuauu ggaugucacg     1200

ccguugagcu ugggcaucga aaccgccggg ggggucauga cgccguuaau caagaggaau     1260

accacgaucc cgaccaagca aacgcaaacg uuuaccacgu auucggauaa ucaaagcagu     1320

gucuuggugc aagucuauga aggggagagg gccaugacca aggauaauaa uuugcucggg     1380

aaauuugauu ugaccgggau ccccccggcc ccgagggggg ucccgcagau agaggugacc     1440

uucgauaucg augcgaaugg gauauugaau gucacggccg cggauaaguc gaccggcaaa     1500

gagaauaaaa uaaccaucac caaugauaag ggccgcuuau cgaaggauga uaucgauagg     1560

auggugcagg aggccgagag guauaagagc gaggacgaag ccaaucgcga uaggguggcc     1620

gccaaaaaug ccuuagagag cuauacguau aauauaaaac aaacggugga ggaugagaag     1680

uuaaggggga agaucucgga gcaggauaag aauaagaucu uagauaagug ccaggaggug     1740

aucaauuggu uggauaggaa ucagauggcg gagaaggaug aguaugagca uaagcagaag     1800

gaguuggaga gggucuguaa uccgaucaua agcaagcucu aucagggggg gccggggggg     1860

ggcucggggg ggggggggag uggggccucg ggggggccga cgauagagga ggucgacuga     1920


<210>  5564
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  5564
augucagucg uagguaucga ccucgguuuu caaaguuguu acguagcggu agcgcgagcu       60

ggagguauag agacgauagc aaacgaauac ucggaccgau gcacuccugc gugcauaucg      120

uucgggccga agaacagguc gauaggggcc gcggcaaagu cgcagguuau cucaaacgcg      180

aaaaacacgg uacaggguuu caagcgauuu cacggucgug cguucucgga cccuuucguc      240

gaggccgaga agaguaacuu agcguacgac auaguucaau uaccgacggg ucucacgggc      300

auuaagguaa cuuacaugga agaggagcgc aacuucacua cggagcaggu aacggcgaug      360

uuguuaucga aguuaaagga aacggcagag ucgguauuaa agaagccagu gguagacugc      420

guaguaucag uaccgugcuu cuacacggac gcggagcggc guucgguuau ggacgccacg      480

cagauagcgg ggcucaacug uuuacgccua augaacgaga cgacggccgu agcguuagcg      540

uacgggauuu acaagcagga cuugccagcg cuugaggaga agccgcgcaa cguuguauuc      600

guggacaugg gacacucggc auaccaggug ucggucugcg cguucaaccg ggggaagcuc      660

aaggucuuag cgacggcguu cgacaccacg uuaggcggac gcaaguucga cgagguacuc      720

guuaaccacu ucugcgagga guucgguaag aaguauaagu uagacauaaa gucgaagauu      780

cgagcguugc uucguuuauc gcaggagugc gagaaguuaa agaaguuaau gucagcgaac      840

gcgucggacu ugccccuuuc gaucgagugc uucaugaacg acguagacgu uucagggacc      900

augaacaggg ggaaguucuu agagaugugu aacgacuuau uggcacgagu cgaaccuccc      960

uugaggucgg ucuuagagca gacaaaguug aagaaggagg acauauacgc gguagagauc     1020

gucggagggg caacgcguau uccggcaguu aaggagaaga uaucgaaguu cuucggcaag     1080

gaguuaucga cgacgcuuaa cgcggacgag gcgguaacga gggguugcgc guuacagugc     1140

gcuauacuuu cuccagcguu caagguacgc gaguucucga uaacggacgu uguuccguac     1200

cccaucaguu uacgguggaa cucgccggcg gaggaggguu cgucggacug cgagguguuc     1260

ucgaagaacc acgcggcgcc cuucucgaag gucuuaacgu ucuaccgaaa agagccguuc     1320

acauuagagg cauacuacag uucgccacag gaccuuccuu acccggaccc ggcgaucgca     1380

caguucucgg uacaaaaggu uacgccccag ucggacgguu cgucgucgaa ggucaaggua     1440

aaggugaggg uuaacguuca cgguaucuuu ucggucaguu cggcgucgcu uguagagguc     1500

cacaagucgg aggagaacga ggagccgaug gagacggacc agaacgcgaa agaggaggag     1560

aaaaugcagg uagaccagga ggagccgcac guagaggagc agcaacagca gacgccggcg     1620

gagaacaagg cggagucgga ggagauggag acuucgcagg cgggcucgaa ggacaagaaa     1680

auggaccagc cuccgcaggc gaaaaaggcg aaggucaaga caucuaccgu cgacuuaccg     1740

auagagaacc aguuauugug gcaaaucgac cgagagaugu uaaacuuaua caucgagaac     1800

gaggggaaaa ugaucaugca ggacaaguug gaaaaggagc gcaacgacgc gaaaaacgcg     1860

guugaggagu acguuuacga gaugcgugac aaguuaucgg gcgaguacga gaaguucguc     1920

ucggaggacg accgaaacuc auucacguua aaguuggagg acacggagaa cugguuauac     1980

gaggacgggg aggaccaacc gaagcaggua uacgucgaca agcuagcgga gcuuaagaac     2040

uugggacagc ccauaaagau cagguuccaa gagagugagg agcgcccgaa gcuauucgag     2100

gaguuaggua agcaaauaca gcaguacaug aagaucauau cuaguuuuaa gaacaaggag     2160

gaccaauacg accacuuaga cgcggcagac augacuaagg ucgagaagag uacgaacgag     2220

gcgauggagu ggaugaacaa uaaguuaaac uuacaaaaca agcagucguu aacgauggac     2280

ccgguaguaa agucgaagga gaucgaggcc aagaucaagg aguuaaccuc uacaugcucg     2340

ccaaucauau cgaagccgaa gccgaaggua gagccgccga aggaggagca gaagaacgcc     2400

gagcaaaacg gccccguaga cggucagggu gacaaccccg ggccucaggc ggcagaacag     2460

gggacggaca ccgcgguacc gucugacucg gacaaaaagu uaccggagau ggacaucgac     2520

uga                                                                   2523


<210>  5565
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  5565
augagcgucg ucgggaucga uuugggguuc uugaauuguu auauagccgu ggcccgcucg       60

ggggggauag aaacgauagc gaacgaauau ucggaucgcu guacgcccgc gugcaucagc      120

cucgggagcc gcaccagggc gauagggaac gccgccaaau cgcaaaucgu gaccaauguc      180

cgcaacacca uccacggguu uaagaaauug cacggcagga gcuucgacga uccgaucguc      240

cagaccgagc gcauacgcuu gccguacgaa uuacaaaaga ugccgaacgg gucggccggg      300

gucaaaguca gauaucucga agaggaacgc ccguucgcca ucgaacaagu caccgggaug      360

uuacucgcga aauugaagga aaccagcgag aacgcccuca aaaagccggu cgccgauugc      420

gucaucagca ucccgucguu uuucaccgac gcggaacgcc gcagcgucau ggccgccgcg      480

caagucgccg ggcucaacug ccuccgccuc augaacgaga ccaccgccgu cgccuuagcc      540

uacgggaucu acaagcaaga cuugccgccg cucgacgaaa agccgcgcaa cgucgucuuc      600

aucgacaugg ggcauagcgc guaccaagug cucgucugcg ccuuuaauaa agggaaguug      660

aaggugcucg ccaccacguu cgacccguac cucggggggc gcaauuucga cgaagcccuc      720

gucgauuauu uuugcgacga auuuaaaacg aaguacaaaa ucaacgucaa ggagaauagc      780

agagcgcucc ucaggcucua ccaagaaugc gagaaguuga aaaaauugau gucggccaac      840

gccagcgacu ugccgcucaa uaucgaaugc uuuaugaacg auuuggacgu cagcucgaag      900

augaaucgcg cccaguucga acaauuaugc gccaguuugc ucgcgcgcgu cgagccgccg      960

cucaaagccg ucauggagca agccaaucuc caaagggagg auaucucguc gaucgagauc     1020

gucggggggg ccaccaggau cccggccguc aaggagcaaa uaaccaaguu uuucuugaag     1080

gauaucucga cgacccucaa cgccgacgag gccgucgccc gcgggugcgc ccuccaaugc     1140

gccaucuuga gcccggccuu caaggucagg gaguucagua ucaccgauuu ggucccguac     1200

agcauaaccc uccgcuggaa aacgagcuuc gaggacgggu cgggcgagug cgaggucuuu     1260

ugcaaaaauc auccggcgcc guuuagcaaa gugaucaccu uucauaaaaa agagccguuc     1320

gaguuggagg ccuucuacac caaccuccau gaggucccgu auccggacgc ccgcaucggc     1380

ucguuuacca uccaaaacgu cuucccgcaa agcgacgggg acucgaguaa ggucaaaguc     1440

aaggucaggg ucaauauaca cgggauauuu ucggucgccu cggccagcgu caucgaaaaa     1500

cagaaccucg agggggacca uucggacgcc ccgauggaaa ccgagaccag cuucaagaac     1560

gagaauaagg acaacaugga caagaugcaa gucgaccaag aggagggcca ccagaagugc     1620

cacgccgagc auaccccgga ggaagagauc gaccauaccg gggcgaagac caaaagcgcc     1680

gugagcgaua agcaagauag gcucaaccaa accuugaaga aggggaaagu aaagucgauc     1740

gacuugccca uacaaucguc guugugccgc caauuggggc aagacuuguu aaauucguau     1800

aucgagaacg aaggcaaaau gauaaugcaa gacaaacucg aaaaggagcg caacgacgcc     1860

aaaaacgcgg ucgaggagua cgucuacgac uuccgcgauc gcuuagggac cguguacgag     1920

aaguuuauaa ccccggaaga ucucucgaaa uuaagcgccg uccucgagga uaccgaaaac     1980

ugguuguacg aggaugggga agaucaaccg aagcaggucu acgucgacaa auugcaggag     2040

uugaaaaagu augggcaacc gauccaaaug aaauauaugg aacacgaaga acgcccgaag     2100

gcgcucaacg aucucgggaa aaaaauacaa uuggugauga aagucaucga agccuaccgc     2160

aauaaagacg agcgcuacga ccacuuagac ccgaccgaaa uggagaaagu cgagaagugc     2220

auaucggacg cgaugucgug guuaaacucg aaaaugaacg cccaaaauaa guugucguug     2280

acccaggacc cggucgucaa ggucagcgag aucgucgcca aaagcaaaga guuagacaac     2340

uuuugcaauc cgauaaucua uaaaccgaaa ccgaaggccg aggucccgga ggauaagccg     2400

aaggccaacu cggaacauaa cgggccgaug gacgggcaau cggggaccga gaccaagagc     2460

gacagcacca aggauucgag ccaacacacc aaaaguagcg gggaaaugga ggucgauuga     2520


<210>  5566
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  5566
augaaauuga guuuagucgc ggccauguua uuauuauugu cggccgccag agcggaagaa       60

gaagauaaaa aagaagaugu cgggaccguc guggggauag auuuaggcac gacguauagu      120

uguguggggg ucuuuaaaaa ugggaggguc gaaauaauag cgaaugacca agggaauagg      180

auaaccccca guuacguggc guuuaccccg gagggcgaga gguuaaucgg ggacgcggcg      240

aaaaaucaau ugacgaguaa uccggaaaau accguguucg augcgaaaag auugauaggg      300

aggaccugga acgaucccag cguccaacaa gauauaaaau uucuccccuu uaaagucguc      360

gagaaaaaga ccaagccgua uauccagguc gacaucgggg ggggccagac caaaaccuuc      420

gccccggagg agaucagcgc gauggucuug accaagauga aggagacggc cgaagccuac      480

cucgggaaaa aagucacgca cgccgucguc accgucccgg cguacuucaa cgacgcgcag      540

aggcaggcca cgaaggaugc cgggaccauc gccggguuga acgucaugcg cauaauaaau      600

gaaccgaccg ccgccgccau cgccuacggg uuagacaaac gcgaaggcga aaaaaauaua      660

uuagucuucg auuuaggggg ggggacguuu gacgucagcu uguugacgau cgauaacggg      720

guguuugagg ucgucgcgac caacggggac acccacuuag ggggggagga uuucgaucaa      780

agggugaugg agcauuuuau aaaguuauau aagaaaaaaa ccgggaagga cgugcgcaag      840

gauaaccgcg ccguccaaaa guugagaagg gaagucgaga aagcgaagag agcguuaagc      900

agccaacacc aggcccgcau cgagaucgaa aguuuuuacg agggggagga uuucagcgaa      960

acguuaacca gagcgaaguu cgaggaauug aauauggacu uauuuagaag caccaugaaa     1020

ccggugcaaa agguccucga ggacagcgac cucaaaaaaa gcgacaucga cgagaucguc     1080

uuggucgggg ggagcaccag gaucccgaaa auccaacagu uagucaagga auuuuuuaac     1140

gggaaagagc cgaguagggg gaucaauccg gacgaggccg ucgccuacgg ggccgccgug     1200

caagccgggg ucuugagcgg ggaccaggac accggggauu uagucuuauu ggacgucugc     1260

ccguugaccu uggggaucga gaccgucggg ggggugauga cgaaguuaau cccgcgcaau     1320

accgucgucc cgacgaaaaa aagccaaaua uucagcaccg ccagcgacaa ccagccgacc     1380

gucaccauaa aaguguacga gggggagcgc ccguuaacca aggauaacca cuuguuaggg     1440

accuucgacu uaaccgggau cccgccggcc ccgaggggcg ugccgcaaau cgaggugacg     1500

uucgaaaucg acgucaacgg gaucuugagg gucaccgccg aggauaaagg gaccggcaau     1560

aagaacaaaa uaaccauaac gaacgaucaa aacagguuaa ccccggagga gauagagcgc     1620

auggucaacg acgccgaaaa auucgccgaa gaggauaaga aauugaaaga aaggaucgac     1680

acccgcaacg aacucgaguc guacgcguac agcuugaaaa accaaaucgg ggacaaggag     1740

aaauuagggg ggaaguugag uagcgaggac aaagaaacga uggagaaggc cgucgaggag     1800

aaaaucgagu gguuagaguc gcaucaggac gccgauaucg aggauuuuaa ggccaaaaaa     1860

aaagaguuag aggagaucgu ccagccgauc auaucgaagu uguacggguc ggccgggccg     1920

ccgccgaccg gggaggaaga caccgccgag aaggacgaac ucuga                     1965


<210>  5567
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  5567
augcaagcgc cgagagaauu ggccgucggg auagauuuag ggacgacgua uagcuguguc       60

ggggucuucc aacaagggag ggucgaaaua uuagcgaaug aucaagggaa uaggacgacc      120

ccgucguaug ucgcguuuac ggauacggaa agauuagugg gcgaugccgc gaaaucgcaa      180

gccgcguuaa auccgcauaa uacggucuuu gacgcgaaaa gauuaauagg caggaaauuu      240

gccgauacga ccguccaaag cgauaugaaa cauuggccgu uuagagucgu cucggaaggg      300

gggaaaccga aagucagggu cuguuauagg ggcgaagaua aaaccuuuua uccggaagaa      360

auaagcagua uggucuuauc gaaaaugaaa gaaaccgcgg aagccuauuu agggcaaccg      420

gucaaacaug ccgucauaac ggucccggcg uacuuuaacg auagccaaag gcaagcgacg      480

aaagaugccg gcgcgauagc cggcuugaau guccucagaa uaauaaacga accgaccgcc      540

gccgcgauag cguacggcuu agauagaaga ggggccgggg aaaggaaugu cuugaucuuc      600

gauuuagggg gcgggacguu ugacgucagc gucuugagua ucgaugccgg gguguucgaa      660

gucaaggcga ccgccgggga cacgcauuua gggggggaag auuuugauaa uagauugguc      720

aaucauuuua uggaggaguu uagaagaaaa cacggcaaag auuuaucggg caauaaaagg      780

gcguuaaggc gcuuaaggac cgcgugcgaa agggcgaaaa ggacguuaag uaguucgacg      840

caagcgacgu uagaaaucga uaguuuauuu gaaggggucg auuuuuauac caguauaacc      900

agggcgaggu ucgaagaguu auguagcgau uuguuuaggu cgacguuaga acccgucgaa      960

aaagcguuaa gagacgcgaa auuagauaaa gcgcaaaucc acgauguggu guuagucggc     1020

gggaguacca ggauaccgaa aguccaaaaa cucuuacaag auuuuuuuaa ugggaaagaa     1080

uuaaauaaau cgauaaaucc ggacgaagcc gucgcguacg gcgccgccgu ccaagccgcg     1140

guccucaugg gcgauaagug cgaaaagguc caagacuugu uauuauuaga cgucgccccg     1200

cucagcuuag gcuuagaaac cgccgggggc gucaugacga ccuuaauaca acgcaaugcg     1260

accauaccga cgaaacaaac gcaaaccuuu acgacguaua gcgauaauca accgggcgug     1320

uuuauacaag ucuacgaagg ggaacgcgcg augacgaaag auaauaauuu auuaggcagg     1380

uucgaguugu cggggauacc gccggcgccg aggggggugc cgcaaaucga agucaccuuc     1440

gauaucgacg ccaacgggau auuaucgguc accgcgaccg aucgcucgac cgggaaagcc     1500

aauaaaauaa cgauaacgaa cgauaaaggg agauuaucga aagaagaagu cgaacgcaug     1560

guccacgagg cggaacaaua uaaagccgaa gacgaagcgc aacgcgaucg cgucgccgcg     1620

aagaauagcu uagaagcgca cguguuucac gucaagggga gccuccagga agagucguug     1680

cgcgauaaaa ucccggagga agaucgcagg aagaugcagg auaaaugcag agagguguug     1740

gcgugguuag aacauaauca auuagccgaa aaagaagaau acgaacacca aaaacgcgaa     1800

uuagaacaga uaugcaggcc gauauuuagu cgcuuguacg gcggcccggg ggugccgggc     1860

gggucgucgu gcgggaccca ggcgaggcaa ggcgauccgu cgacggggcc gauaaucgaa     1920

gaagucgacu ga                                                         1932


<210>  5568
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__P48741__HsHSPA7

<400>  5568
augcaggcgc cccgcgagcu ggccgugggc aucgaccucg ggaccaccua cagcugcguc       60

ggcguguucc agcaggggcg gguggagauc cuggccaacg accagggcaa ccgcacgacc      120

ccguccuacg ucgccuucac cgacaccgag cggcuggugg gggacgccgc caagucgcag      180

gccgcgcuca acccccacaa cacgguguuc gacgccaagc gcuuaaucgg ccggaaguuc      240

gccgacacca ccguccagag cgacaugaag cacuggcccu uccagguggu gucggagggc      300

gggaagccca aggucagggu gugcuaccgg ggcgaggaca agaccuucua cccggaggag      360

aucagcagca ugguguuauc caagaugaag gagacggccg aggcguaccu cgggcagccc      420

gucaagcacg ccgugaucac cgugcccacc uacuucucga acagccagag gcaggccacc      480

aaggacgccg gcgccaucgc ggggcugaag gucuuaccca ucaucaacga ggccacggcc      540

gccgccaucg cguacggccu cgacagacgc ggcgccggga agcggaacgu gcugaucuuc      600

gacuuaggcg ggggcaccuu cgacgugagc gucuugagua ucgacgccgg cguguucgag      660

gugaaggcca ccgccgggga cacccacuua ggcggggagg acuucgacaa ccgccugguc      720

aaccacuuca uggaggaguu cagacgcaag cacggcaagg accucucggg gaacaagcgg      780

gcguuaaggc gguuaaggac ggccugcgag cgggccaaga ggaccccgag uagcuccacc      840

caggccaccc ucgagaucga cagcuuauuc gagggcgugg acuucuacaa gaguaucacg      900

cgggccaggu ucgaggaguu augcagcgac uuguucaggu ccaccuuaga gcccguggag      960

aaggcguuaa gagacgccaa gcucgacaag gcccagaucc acgacuucgu cuuaggcggg     1020

ggccugcaca gccaccccca gggggccgag guggcggccg gccuccugca gcgccagggg     1080

gccgagcagg agcaccagcc cuga                                            1104


<210>  5569
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  5569
augucgaagg ggccggcggu agguauagac uuaggcacga cguacucgug cguaggggua       60

uuccagcacg gcaagguaga gaucaucgcg aacgaccagg ggaaccgaac aacgccgucg      120

uacguagcau ucaccgacac ggagcgcuua auaggcgacg cggcgaagaa ccagguagcg      180

augaacccga cuaacacggu cuucgacgcg aagcgguuaa ucggucgacg guucgacgac      240

gcgguaguac agucggacau gaagcacugg cccuucaugg ucguuaacga cgcagguaga      300

ccgaagguac agguggagua caagggcgag accaagucgu ucuacccgga ggaggucucg      360

ucgauggugu uaaccaagau gaaggagauc gcggaggcgu acuuggguaa gacggugacg      420

aacgcagucg uuacgguccc ggcguacuuc aacgacaguc agcgacaggc gacuaaggac      480

gcggguacga ucgcgggauu aaacgucuua cgaaucauca acgagccgac ggcggccgcg      540

auagcguacg ggcuagacaa gaagguaggu gcggagagga acguauuaau cuucgacuug      600

gggggcggga cguucgacgu aucgauauua accaucgagg acgguauuuu cgagguaaag      660

aguaccgcag gggacaccca cuuagggggg gaggacuucg acaaccguau gguaaaccac      720

uucauagcgg aguucaagcg gaagcacaag aaggacauau cggagaacaa gcgcgccgua      780

cgacguuuac ggacggcgug cgagagagcg aagcgaaccu uaaguucgag uacucaggca      840

ucgauagaga uagacucguu auacgagggg aucgacuucu acacgucgau cacgcgagcg      900

cgguucgagg aguugaacgc cgacuuguuc cgagggacgc uugacccggu ggagaaggcg      960

uuacgggacg cuaaguuaga caagagucag auacacgaca uaguauuagu aggggggucg     1020

acgcgaaucc cuaagauaca gaaguuauug caggacuucu ucaacggcaa ggaguuaaac     1080

aagaguauaa acccggacga ggcaguagcc uacggggcgg cgguacaggc ggcgauucuc     1140

ucgggugaca agucggagaa cgugcaggac uuauuauuau uagacguaac gcccuuaucg     1200

cucgggaucg agacggcggg ggggguaaug acgguauuga ucaagaggaa cacgacgaua     1260

ccgacgaagc aaacgcagac guucacgacc uacucggaca accagccggg cguauuaaua     1320

cagguauacg agggcgagcg ggccaugacg aaggacaaca accuuuuagg uaaguucgag     1380

uuaacgggua uuccgccggc gccgaggggg guaccgcaaa ucgagguaac guucgacaua     1440

gacgcgaacg ggauccuuaa cguaagugcg guagacaagu cgacggguaa ggagaacaag     1500

aucacgauaa cgaacgacaa gggccgcuua aguaaggagg acaucgagcg caugguacag     1560

gaggcggaga aguacaaggc ggaggacgag aagcagcgag acaagguauc gucgaagaac     1620

ucguuggaga guuacgcguu caacaugaag gcgacgguag aggacgagaa guuacagggu     1680

aagaucaacg acgaggacaa gcagaagauc uuggacaagu gcaacgagau aaucaacugg     1740

uuagacaaga accagacggc ggagaaggag gaguucgagc accagcaaaa ggaguuagag     1800

aagguaugca acccgaucau aacgaagcua uaccaguccg cgggugggau gccggggggg     1860

augccgggcg guuuccccgg agggggugcc ccgccgagug ggggggcguc gucgggcccg     1920

acgaucgagg aggucgacug a                                               1941


<210>  5570
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  5570
augaucucgg cgucgagggc cgccgccgcg agguuggucg gggcggccgc gaguagaggg       60

ccgaccgcgg cgaggcauca agacucgugg aacggguugu cgcacgaagc cuuccgcuug      120

gucagccgca gagacuacgc cagcgaggcg auaaaagggg ccgucgucgg gaucgaucuc      180

gggaccacga auaguugugu cgccgucaug gaggggaagc aagcgaaagu cuuagaaaac      240

gcggaggggg cgcgcacgac gccgagcguc gucgcguuca ccgccgacgg ggaaagguug      300

gucgggaugc ccgcgaaaag gcaagccgug acgaauccga auaauaccuu cuacgccacg      360

aaaagguuga ucgggagaag guacgacgac ccggaggucc aaaaggauau caagaacguc      420

ccguuuaaga ucgugagggc gaguaacggg gacgcguggg ucgaagccca uggcaagcuc      480

uacagccccu cgcaaauagg ggccuucguc cucaugaaaa ugaaggaaac cgccgagaac      540

uaucucggcc auaccgccaa gaacgccguc auaaccgugc cggccuacuu uaacgauagc      600

caacgccaag cgaccaaaga cgccgggcaa auuagcgggu uaaacgucuu gagagucauc      660

aacgaaccga ccgccgccgc cuuggcguac ggguuggaua agagcgagga uaagguaauc      720

gccgucuacg accucggggg ggggaccuuc gacaucagca uauuagagau ccaaaagggg      780

gucuucgaag ucaagaguac caacggcgac acguuucucg ggggcgagga uuucgaucaa      840

gcgcucuuga gacauaucgu caaagaauuu aaacgcgaaa ccggcgucga ccucaccaaa      900

gauaauaugg ccuugcaacg cgucagagag gccgccgaga aagccaagug cgaguugagu      960

agcagcgucc aaaccgauau aaaccucccg uacuugacca uggacagcag cgggccgaaa     1020

caccucaaca ugaaacucac gagggcccag uucgagggca ucgugaccga cuugauacgc     1080

cgcaccauag ccccguguca aaaggccaug caggacgccg agguaucgaa aucggauauc     1140

ggggagguca uauuggucgg ggggaugacc cgcaugccga aaguccaaca aaccguccaa     1200

gauuuguucg ggcgcgcgcc gucgaaagcc gugaacccgg acgaagccgu cgcgaucggg     1260

gccgcgaucc aagggggggu ccucgcgggg gacgugaccg acgucuuauu guuggacgug     1320

accccgcuca gcuuagggau cgagaccuug gggggggugu ucacgaaguu gaucaaccgc     1380

aacacgacca ucccgacgaa aaaaucgcaa gucuuuagca ccgcggccga cgggcagacc     1440

caggucgaga ucaaggucug ucaaggggag cgcgaaaugg ccggggauaa uaaguuguug     1500

gggcaauuca cccucaucgg gaucccgccg gcgccgaggg gggucccgca aaucgagguc     1560

accuucgaua ucgacgcgaa cggcaucguc cacgucagcg ccaaggacaa ggggaccggg     1620

agggaacaac aaaucgucau acaaagcagc ggggggcucu cgaaggacga caucgagaac     1680

auggucaaaa acgccgaaaa auacgccgag gaggauagaa ggaaaaaaga gagggucgag     1740

gcggucaaua uggccgaggg gauaauccau gauaccgaaa cgaaaaugga agaguuuaaa     1800

gaucagcucc cggccgacga auguaauaaa uuaaaggagg aaaucaguaa gaugcgcgaa     1860

uuguuagccc gcaaagauuc ggaaaccggg gagaacaucc gccaagccgc gaguagcuug     1920

caacaagcca gcuuaaaauu auuugagaug gccuauaaaa aaauggccag cgaaagggag     1980

gggagcgggu cgagcgggac cggcgagcaa aaagaggacc agaaagaaga gaaacaauga     2040


<210>  5571
<211>  2028
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_079291.2__HsHSPA12A

<400>  5571
auggcagaca aggaagcagg ggguucggac ggcccucgug agacugcacc uacuucggcg       60

uacucuucgc cggcucgauc guuaggugac acugggauca cgccguuaag uccgucgcac      120

auaguaaacg auacggacag uaacguaucg gagcagcagu cguucuuagu aguaguagcg      180

guggacuucg guaccacguc gucggguuac gcguacucgu ucacgaaaga gccggagugc      240

auacacguca ugcggaggug ggagggggga gacccgggcg uaaguaacca gaagacaccu      300

acgacgauau uauuaacgcc ggagcggaag uuccacucgu ucgguuacgc ggcccgugac      360

uucuaccacg acuuagaccc aaacgaggca aagcaauggu uauacuugga gaaauucaaa      420

augaaguuac acacuacggg agacuuaacg auggacacug acuugacugc cgcgaacggu      480

aaaaagguaa aggcgcucga gaucuucgcg uacgcauuac aguacuucaa ggagcaggcc      540

uuaaaggagc ucucugacca ggcuggguca gaguucgaga acagugacgu aaggugggua      600

auaacuguac cggcgauaug gaagcagcca gcgaagcagu ucaugcgcca ggcagcguac      660

caggcggggu uagcgucgcc ggagaacagu gagcaguuaa uaaucgcuuu agaaccggaa      720

gcggcgucga uauacugccg gaaguuacgu uuacaccaaa ugauagaguu aucaaguaag      780

gcggcgguua acggguacuc agguucggac acuguugggg cggguuucac gcaggcgaag      840

gagcacaucc gacgaaacag gcaaucgcgc acauuccucg ucgagaacgu uauuggcgag      900

auuuggagug agcuugagga gggagacaag uacguaguag uagacucggg ugggggaacu      960

guugauuuaa cgguacacca aauuaggcuc ccagaggguc acuuaaagga gcucuacaag     1020

gccacgggug guccguacgg uagucucggg guugacuacg aguucgagaa guugcucuac     1080

aagaucuucg gugaggacuu cauagagcag uuuaagauca agcguccggc ggcgugggua     1140

gaccucauga uagcuuucga aucgcgaaag cgcgccgcag cgccggaccg aacgaacccu     1200

uugaacauca cguuaccguu cucguucaua gacuacuaca agaaguuccg uggacacucg     1260

guagagcacg cguuacgaaa gaguaacgua gacuucguaa aguggucgag ucaggguaug     1320

cuucgcaugu cgcccgacgc gaugaacgcg uuauucaagc cuacuaucga cucgauaaua     1380

gaacacuuga gggacuuauu ccagaagccg gagguaucga cgguaaaguu cuuauucuua     1440

gucggggggu ucgcagaggc gccguuguua cagcaggcag uucaggcggc guucggugac     1500

cagugccgaa uaauaauacc ccaggacgua ggguuaacga ucuugaaggg ggcgguuuua     1560

uucggguuag acccggccgu aauaaagguu cgacguucac ccuugacuua cggugucggc     1620

gucuuaaacc gauacguaga ggggaagcac ccaccggaaa aguuguuagu caaggacgga     1680

acacgauggu gcacggacgu auucgacaag uucauaucgg ccgaccaaag uguagcguua     1740

ggcgaguuag uaaagcgauc guauacgccu gccaagccgu cgcaauuagu aauagucauc     1800

aacaucuaca guucggagca cgacaacgua aguuuuauaa cggacccggg agucaagaag     1860

ugcggaacau uaagguuaga cuugacgggu acgucgggua ccgcgguucc agcgcgccga     1920

gagauacaga cgcucaugca guucggugac acggagauaa aggcgacggc gauagacauc     1980

gcuacgucua agucgguaaa ggucgguauc gacuuucuca acuacuga                  2028


<210>  5572
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  5572
auguuagcag uacccgagau gggauuacaa gguuuauaca uagguucguc gcccgagcgu       60

ucgccgguuc cgucgccucc ggggucgcca cgcacgcaag agucgugcgg gauagcaccu      120

uuaacuccuu cccagagucc uaagccggaa guucgugcac cgcagcaggc aucguucagu      180

gucguagucg cuauagacuu cgguacaaca ucgucggguu acgccuucuc guucgcuucg      240

gacccggagg caauccauau gaugcguaag ugggagggug gugacccugg ugucgcgcac      300

caaaagacgc cuacgugcuu auuauuaacg ccugaggggg cguuccacuc guucggauac      360

acggcgcgag acuacuacca cgacuuggac cccgaggagg cucgcgacug guuauacuuc      420

gaaaaguuca aaaugaagau acacucggcg acugacuuaa cguuaaagac acaacucgag      480

gcgguuaacg ggaagacaau gccggcguua gaggucuucg cgcacgcguu gagguucuuc      540

cgcgagcacg cgcuccagga guuacgagag caaucgccgu cauugccgga gaaagacacg      600

guccguuggg ucuuaaccgu cccggcgauc uggaagcaac cggcgaaaca guucaugcga      660

gaggcggcuu auuuagcggg guuaguaucg cgugagaacg cggagcaauu auuaauagcg      720

uuagagccgg aggcggcguc aguuuacugu cgaaaguugc gauugcacca guuguuagau      780

uuaucaggaa gggcgccggg aggcgggcga uugggcgaga ggcgaucgau agacucgucg      840

uuccgacagg cgcgcgagca gcuccgucgu ucgaggcauu cgcggacguu cuuaguagag      900

ucggguguug gugaguuaug ggcggaaaug caggcgggug accguuacgu agucgcugac      960

ugcggugggg ggacgguaga cuuaacaguu caccaguuag agcagccaca cgguacguug     1020

aaagagcuuu acaaggcguc aggagggccg uacggggccg uagggguuga uuuagcguuc     1080

gagcaguugc ucugccggau cuucggcgag gacuucaucg caacauucaa gcgccagcgu     1140

ccagcggcau gggucgacuu aacaauagcg uucgaggcac guaagcggac ggcaggaccg     1200

caucgagcgg gugcauuaaa cauaaguuua ccguucucgu ucauagacuu cuaccggaag     1260

caacgcgguc acaacguaga gacggcgcuc aggcgaaguu cggucaacuu cguaaagugg     1320

aguucgcagg guauguugcg caugaguugc gaggcgauga acgaguuauu ccagccaaca     1380

guuucaggca uuauacagca cauugaggca uuauuggcgc gccccgaggu acaggggguc     1440

aagcucuuau ucuuggucgg aggauucgcg gagucggcag uauuacagca cgcaguacaa     1500

gcggcuuuag gugcgagggg cuuacgcgua guaguacccc acgacgucgg uuugacuaua     1560

uugaagggcg ccguuuuauu cggucaggcu ccgggagucg ucaggguucg acggucucca     1620

uuaacuuacg gugucggugu auuaaaccgu uucguccccg guaggcaccc gccggagaag     1680

uuauugguac gagacggucg aagguggugc acggacgugu ucgagcguuu cguagcagcg     1740

gaacagucag ucgcguuagg agaggaggua aggcguucgu acuguccugc aaggccagga     1800

cagcgucgag ucuuaauuaa cuuguauugu ugcgcagcgg aggacgcacg auucauaacu     1860

gacccgggug uacggaagug cggugccuua aguuuggagu uagaaccggc ggacugcggu     1920

caggacacgg cgggugcacc accgggucgu cgagagaucc gagcagcgau gcaauucggu     1980

gauacugaga uaaaggugac ggcgguagac guuucgacua acaggucggu ccgagcaucg     2040

aucgacuucu uaucgaauug a                                               2061


<210>  5573
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_008879.3__HsHSPA13

<400>  5573
auggcgcgcg aaaugacuau acucgggucu gcggucuuaa cguuacucuu agcagguuac       60

uuagcgcagc aguaccuucc ucuuccgaca cccaagguaa uaggaauaga cuuagguacg      120

acauacugca gugucggagu auucuucccg ggaacuggua aggucaaggu aauaccggac      180

gagaacggac acaucucuau cccgucgaug gucucguuca cggauaacga cguuuacguc      240

ggguacgagu cggucgaguu agcggacucu aacccgcaga acacgaucua cgacgcuaag      300

cgauucaucg guaagauauu cacggcggag gaguuagagg cagagauagg uagguacccg      360

uucaaggucu ugaacaagaa cgggauggua gaguucucag uaaccucgaa cgagacgauc      420

acuguaaguc ccgaguacgu cgguucacgu uuacuauuaa aguugaagga gauggcggag      480

gcguacuugg gcaugccggu agcgaacgca guaauaucgg uccccgccga guucgacuua      540

aagcaacgaa acucgacgau cgaggcggcg aacuuagcgg ggcuuaagau ccuucgagug      600

aucaacgagc cgacggcggc ggcgauggcc uacggguuac acaaggccga cguauuccac      660

gugcuuguca ucgacuuagg aggugggaca cucgacgucu cgcuuuugaa caagcagggu      720

ggaauguucu ugacgcgugc gaugucgggu aacaacaagu ugggugggca ggacuucaac      780

cagcgauuau uacaguacuu guacaagcaa auuuaccaga cguacgguuu cgucccguca      840

cgaaaggaag agauacaucg auuaaggcag gcagucgaga ugguaaaguu gaacuugacg      900

uuacaccagu cggcgcaauu aagugucuug uuaacgguug aggagcagga ccguaaggag      960

ccgcacucgu cggacaccga guuaccgaag gacaaguugu cgucggcuga cgaccacagg     1020

guaaacucgg guuucggcag ggguuuauca gacaagaagu cgggcgaguc gcagguacuc     1080

uucgagacgg agaucagucg aaaguuauuc gacacguuaa acgaggacuu auuccaaaag     1140

aucuuaguuc cgauccagca gguuuuaaag gagggucacu uagagaagac ggagauagac     1200

gagguugucu uggucggugg uucgacgcga aucccccgaa ucaggcaggu aauacaggag     1260

uucuucggga aggacccaaa cacgucgguc gauccggacu uagcgguugu uaccgguguu     1320

gcgauucagg ccgggauaga cggggguucg uggccguuac agguaucagc gcucgagaua     1380

ccgaacaagc acuugcagaa gacgaacuuc aacuga                               1416


<210>  5574
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  5574
auggccgcga uaggggucca uuuagggugu acgagcgcgu gcgucgcggu guacaaagac       60

gggagagccg gggucgucgc caacgacgcg ggggauaggg ucaccccggc cgucgucgcc      120

uauagcgaga acgaggaaau cgucgggcuc gccgccaagc agucgcgcau ccgcaacauc      180

agcaauaccg ucaugaaggu caaacaaaua uuagggcgcu cgaguucgga uccgcaggcg      240

caaaaguaua uagccgaguc gaagugccuc gugaucgaaa agaacggcaa gcucagguac      300

gagaucgaca ccggggagga gaccaaguuc gucaauccgg aggacgucgc gcgcuuaauu      360

uuuucgaaaa ugaaggagac cgcccacagc guccucggga gcgacgccaa cgacgucguc      420

aucaccgugc ccuucgacuu cggggaaaaa cagaagaacg ccuuggggga ggccgcccgc      480

gccgccgggu ucaacguccu caggcucauc caugaaccca gcgccgccuu guuggccuac      540

gggaucgggc aggauagucc gaccgggaag ucgaacaucc ucgucuuuaa auuggggggg      600

accagucuca gcuugucggu gauggagguc aauucgggga ucuacagagu cuugagcacg      660

aauaccgacg acaauauagg gggggcccau uuuaccgaga cgcucgccca auacuuggcc      720

agcgaauuuc agcgcaguuu uaagcacgac guccgcggga acgccagggc gaugaugaag      780

cucaccaauu cggccgaggu cgccaaacac agccucagca cgcucggguc ggcgaauugc      840

uuuuuggaua gccucuacga ggggcaggac uucgacugua acgucagucg cgcccgcuuc      900

gaguuguugu gcagcccguu guucaacaaa ugcaucgagg ccauacgcgg guugcucgac      960

cagaacgggu uuaccgccga cgacauaaau aaagucgugu ugugcggggg cagcagcagg     1020

auaccgaaau ugcaacaauu aaucaaggac uuguuuccgg ccgucgaauu guugaacagc     1080

auaccgccgg acgaggucau accgaucggg gccgccaucg aggccgggau cuugaucggc     1140

aaggagaauu uacucgucga agauagcuug augaucgaau gcagcgcgcg cgacauccuc     1200

gucaaagggg ucgaugagag cggggcgucg cgcuuuaccg ucuuauuccc gagcggcacc     1260

ccgcucccgg ccaggcgcca gcauacccuc caagcgccgg ggucgaucag cagcgucugu     1320

uuggaguugu acgaaagcga cggcaaaaau agcgcgaaag aagagacgaa auucgcccaa     1380

gucgucuugc aagaucucga uaagaaggag aacgggcuca gggacauccu cgccgucuug     1440

accaugaagc gcgacgggag ccuccacguc accuguaccg accaagaaac cgggaagugc     1500

gaggccauaa gcaucgaaau cgccagcuga                                      1530


<210>  5575
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  5575
auguccgugg uaggacucga cgucgggagc caaagcugcu acauagcggu agccagggca       60

ggcgggauag agacgaucgc caacgaguuc uccgaucgcu gcacacccag cgucaucagc      120

uuugguucua aaaacaggac uauaggagug gccgcgaaaa accaacaaau aacccaugca      180

aacaacaccg ucagcaacuu caaacgauuc cacggacgug ccuucaacga cccguuuaua      240

caaaaagaaa aagaaaaccu auccuacgac cuaguccccc ucaagaaugg aggcgugggc      300

aucaaaguua uguauauggg agaagaacac uuguucucag uagaacagau aaccgccaug      360

cuacuaacaa aacugaagga aaccgcagag aacagucuga agaaaccugu caccgacugc      420

guaaucuccg uacccuccuu cuucaccgac gcagaacgga gauccguacu agacgcagcc      480

caaauaguag gccuaaacug ccuccgcuug augaacgaua ugacggccgu agcacucaac      540

uaugggauuu acaaacaaga ccucccaagc cucgacgaaa aaccccgcau aguagucuuc      600

gucgacaugg gacacucagc auuccaggua agcgcaugcg ccuucaacaa aggaaaacuc      660

aaagucuuag gcacggcuuu cgaccccuuc cuaggcggga aaaauuucga cgagaaacuc      720

gucgaacacu ucugcgccga guucaaaacc aaauacaaac ucgacgcaaa gagcaaaauc      780

cgagcccucc uacgcuuaua ccaggaaugc gaaaagcuaa agaaauugau guccuccaac      840

uccaccgacc uacccuuaaa caucgaaugu uucaugaacg acaaggacgu cagcggaaag      900

augaacagau cccaguucga ggagcucugc gccgaguuau uacaaaagau agaagucccc      960

cucuacagcc uucucgaaca gacccaccuc aaaguagaag acguuucagc cgucgaaauc     1020

gucggcggag caacacgcau ccccgcgguc aaagaacgca ucgccaaauu cuucgggaag     1080

gacauaucca ccacccuaaa cgcagacgaa gcaguggcac gcgggugugc ccuccagugc     1140

gccaucuuaa gccccgcauu caaaguacga gaguucucag uaaccgaugc cgucccguuc     1200

ccaauaagcc ugauauggaa ccacgacagc gaggacaccg aaggugucca cgaagucuuc     1260

agucgaaacc acgcggcccc auucucaaaa guauuaacgu uccuccgacg cggacccuuc     1320

gaacucgaag cauucuacag cgacccgcaa ggcguaccgu acccugaggc aaagauuggc     1380

agguucguag uccagaacgu cuccgcacaa aaagauggcg agaaaagccg cguaaagguc     1440

aaaguccgag ucaauacaca cggaaucuuc accauuucca ccgccucaau gguagaaaaa     1500

guccccacag aagaaaacga gaugagcucu gaagccgaca uggagugccu caaccaacgc     1560

ccacccgaaa accccgacac cgacaagaac guccaacaag acaacagcga agcaggaacc     1620

cagccccaag uccaaaccga cgcacaacag accagccaga gcccacccuc ccccgagcuc     1680

acaucagaag aaaauaagau cccagacgca gacaaggcca acgaaaagaa agucgaccag     1740

cccccggagg ccaagaaacc caaaaucaaa guggucaacg uagaacuccc caucgaagca     1800

aaccuggucu ggcagcuagg uaaagacuua uuaaacaugu acaucgaaac cgaaggcaaa     1860

augauaaugc aagauaaacu cgaaaaagaa cgcaacgacg ccaaaaacgc agucgaagaa     1920

uacguauacg aguuccggga caaauuaugc ggcccauacg aaaaauucau cugugaacaa     1980

gaccaccaaa acuuucuacg uuuauuaacc gaaaccgaag acuggcucua cgaagaaggc     2040

gaagaucaag caaaacaggc uuacgucgau aaacucgaag aacuaaugaa aaucggaacg     2100

ccggucaaag ugcgguucca agaagcagaa gaacguccca aaauguucga ggaacucgga     2160

caaagacucc aacacuacgc gaaaaucgcc gccgacuucc gcaacaaaga cgagaaguac     2220

aaccacaucg acgaaucaga aaugaagaaa guagaaaagu cggucaacga aguaauggaa     2280

uggaugaaca acguaaugaa cgcccaagcc aaaaaguccc ucgaccaaga cccagucguc     2340

cgagcacaag aaaucaaaac caaaauuaag gaacucaaca auaccugcga gcccgucgua     2400

acgcaaccga aaccaaaaau agaauccccc aaacucgaac gaacccccaa cgggccgaac     2460

aucgacaaga aagaagaaga ccucgaggac aaaaacaacu ucggagcaga accaccacac     2520

caaaacggcg aaugcuaccc aaacgagaaa aacagcguca acauggaccu cgauuga        2577


<210>  5576
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  5576
auggccgaua agguccgccg ccaacgcccc cgccgcaggg ugugcugggc gcucgucgcc       60

gucuugcucg ccgauuuacu cgccuuaucg gacaccuuag ccgucaugag cgucgauuua      120

gggucggaaa guaugaaagu cgcgaucgug aagccggggg ucccgaugga gaucgugcuc      180

aacaaagaga gcagacgcaa gacccccguc auagucacgu uaaaggagaa cgagcgcuuu      240

uucggggauu cggccgccuc gauggccauc aaaaacccga aagccaccuu gagguauuuu      300

caacauuugu uaggcaaaca agccgacaau ccgcacgucg ccuuguauca agcgagguuu      360

cccgaacaug aauuaaccuu ugauccgcaa cgccaaaccg uccauuucca aauaucgagc      420

caauuacaau uuagcccgga agagguccuc gggauggucu ugaacuacag caggagcuug      480

gccgaggacu ucgccgaaca accgauaaaa gacgccguca uaacgguccc gguguuuuuu      540

aaucaagcgg aaaggagggc cgucuuacaa gccgccagga uggccggguu gaaggucuua      600

caauugauaa acgauaauac ggcgaccgcg uugucguacg ggguguuuag gagaaaggac      660

aucaauacga ccgcgcaaaa cauaauguuu uacgauaugg ggagcggguc gacggucugu      720

acgaucguca cguaucaaau ggucaaaacc aaagaggccg gcaugcaacc gcaauuacaa      780

auaagagggg ucggguucga uaggacguua ggcggguuag aaauggaauu gagauugagg      840

gagagguuag ccggcuuguu uaacgaacaa aggaaagggc aacgcgccaa agacgucaga      900

gaaaauccca gggcgauggc gaaauuauua agggaagcca acagauugaa gacgguguug      960

ucggcgaaug ccgaucauau ggcccaaauc gagggguuaa uggacgacgu cgauuuuaaa     1020

gccaagguca ccagggucga guucgaagaa cucugcgccg aucucuucga aagagucccg     1080

ggcccggucc aacaagcguu gcaaucggcg gagaugucgu uagacgaaau cgaacaaguc     1140

auauuagucg ggggcgcgac cagagugccg cgcguccaag aagucuuauu aaaagcgguc     1200

gggaaagaag aauuaggcaa aaauauaaac gccgacgagg ccgcggcgau gggcgccguc     1260

uaucaagccg ccgccuuguc gaaggcguuc aaggucaaac cguucguggu gagggacgcc     1320

gucguguauc cgauauuagu cgaauuuacc cgcgaagucg aagaagaacc gggcauccau     1380

ucguuaaaac auaacaagag agucuuguuu agcagaaugg gcccguaucc gcagaggaag     1440

gugauaacgu ucaauaggua uucgcacgac uuuaauuuuc auauaaauua uggggauuua     1500

ggguuuuuag gcccggagga cuugagaguc uucgggaguc aaaacuuaac gaccgucaaa     1560

uugaagggcg ucggggauuc guuuaaaaaa uacccggauu augaaaguaa agggauaaaa     1620

gcccauuuua auuuagacga aucggggguc uugucguugg aucgcgucga aagcgucuuc     1680

gaaaccuuag ucgaagauuc ggccgaggaa gagagcaccu ugacgaaguu ggggaauacg     1740

aucaguucgu uauucggggg ggggacgacc ccggacgcga aagaaaacgg gaccgacacc     1800

gugcaagaag aggaagaauc gccggccgaa ggcucgaaag augaaccggg cgaacaaguc     1860

gaauugaaag aagaggccga agcgccgguc gaagacggga gccaaccgcc gccgccggag     1920

ccgaaagggg acgccacgcc ggaaggggag aaagcgaccg agaaggagaa cggcgauaaa     1980

agcgaagcgc aaaagccguc ggaaaaagcc gaagccggcc cggaaggggu ggccccggcg     2040

ccggaagggg aaaaaaaaca aaaaccggcg cgcaaaagaa ggauggucga agaaauaggc     2100

gucgaauuag ucgucuuaga uuuaccggau cucccggaag acaaauuagc ccaaagcguc     2160

caaaaguugc aagaucucac cuugagggau uuagaaaaac aagagagaga gaaggccgca     2220

aauucgcucg aggccuuuau cuucgaaacg caagauaaau uauaucaacc ggaauaucaa     2280

gaggucagua ccgaagaaca aagggaagaa auaagcggca aauugucggc ggccaguacg     2340

ugguuagaag acgaaggggu cggggcgacg accgucaugc ucaaagaaaa auuagccgaa     2400

uuacgcaaau uaugucaggg cuuauucuuc agagucgaag aaaggaaaaa auggccggag     2460

agauuaagcg cguuggacaa cuuguugaau cacaguucga uguuuuugaa aggcgcgaga     2520

uugauaccgg aaauggauca aauauuuacc gaagucgaaa ugaccacccu cgaaaaggug     2580

auaaacgaaa cgugggcgug gaaaaacgcc accuuagcgg aacaagccaa auuaccggcg     2640

accgaaaaac cgguccucuu gagcaaggau aucgaggcca aaaugauggc guuagauagg     2700

gaaguccaau acuuauugaa caaagcgaaa uucacgaaac cgagaccgag accgaaagau     2760

aaaaacggca cgagagccga accgccguug aacgcgucgg cgucggauca aggcgaaaaa     2820

gugauaccgc cggccgggca aaccgaggac gccgaaccga ucagcgagcc ggaaaagguc     2880

gaaaccggga gugaaccggg ggauaccgaa ccgcucgaac ucggggggcc gggggccgag     2940

ccggagcaaa aggagcagag caccgggcaa aaaagaccgc ucaaaaauga ugaguuguga     3000


<210>  5577
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  5577
augccggagg agacgcaaac gcaggaucag ccgauggagg aagaggaggu agagacauuc       60

gcauuccagg cggagauagc acaauuaaug ucguuaauaa uuaacacguu cuacaguaac      120

aaggagauau ucuuaaggga guuaauaucg aacucgucgg acgcguugga caaaauacga      180

uacgaaucgu uaacggaccc gucgaaguua gacucgggua aggaguugca caucaacuua      240

auuccgaaca agcaggaccg gacguuaacg auaguagaca cggguauagg aaugacgaaa      300

gcggacuuga uaaacaacuu aggaacgaua gcgaagucgg guacuaaggc guucauggag      360

gcauuacagg cgggugcgga cauaaguaug auaggucaau ucggggucgg auucuacucg      420

gcauacuuag ucgcagagaa gguaacggua aucacgaagc acaacgacga cgaacaauac      480

gccugggaga guucggcggg ugguaguuuc acgguacgca cugacacggg ugagccgaug      540

gguaggggua cgaagguaau auuacacuua aaggaggacc agacggaaua cuuagaggag      600

cgccggauca aggagauugu uaaaaagcac ucgcaauuca ucggcuaccc uauaacguua      660

uucgucgaga aggagcgcga caaggagguu agugacgacg aggcggagga gaaagaggac      720

aaggaggagg agaaggaaaa ggaggagaag gagucggagg acaagccgga gauagaggac      780

guaggaucgg acgaggagga ggagaagaag gacggggaca aaaagaagaa gaaaaagaua      840

aaggagaaau acauagacca agaggaguua aacaagacga agccgaucug gacaaggaac      900

ccggacgaca uaacgaacga ggaguacggu gaguucuaca agucguuaac aaacgacugg      960

gaggaccacu uagcggucaa acacuucagu guagaggggc aguuagaguu ccgcgcguug     1020

uuauucguac cgaggcgcgc gccguucgac uuauucgaga accggaagaa gaaaaacaau     1080

auaaaguuau acguccgaag gguauucaua auggacaacu gcgaggaguu aauuccggag     1140

uaccucaacu ucauacgcgg ugucgucgac ucggaagacu ugccguuaaa caucucgcga     1200

gagauguuac agcagucgaa gaucuuaaag guaauacgca agaacuuagu caagaagugc     1260

uuagaguuau ucacggaguu ggcagaggac aaggagaauu acaaaaaauu cuacgagcag     1320

uucucgaaga auauaaaguu agggauacac gaggacaguc agaaccgaaa aaaguuauca     1380

gaauuauuac gauacuauac gagugcgucg ggggacgaaa uggucaguuu gaaggacuau     1440

uguacacgga ugaaggaaaa ccaaaagcac auauacuaca uaacggggga gacgaaggac     1500

caaguugcga acucggcauu cgucgagcgc uuacggaagc acggguuaga ggucauauac     1560

augaucgaac cuauagacga guauugcgua cagcaauuga aggaguucga ggggaagaca     1620

uuaguaagug uaacaaagga gggguuagag uugccggagg acgaggagga gaagaagaag     1680

caggaggaga agaagacgaa guucgagaac uuaugcaaga uaaugaagga cauauuagag     1740

aagaaggucg agaaggucgu cgucucuaac agguugguaa cgucgccgug cugcauagua     1800

acgucgacuu acgguuggac ugcgaacaug gaacgaauaa ugaaggcgca ggcguuaagg     1860

gacaacagua cgauggguua cauggcggca aagaagcauu uagaaaucaa cccggaccac     1920

ucgaucauag agacguuacg acagaaggcg gaggcggaca agaacgacaa gagugucaaa     1980

gacuuaguaa uauuauuaua cgagacggcg uuguuaucga guggguucuc guuagaggac     2040

ccacaaacuc acgcgaaccg aauauaucgc augauaaagu ugggauuagg aaucgacgag     2100

gacgacccga cggcggacga cacaucggcg gccguaaccg aggagaugcc gccguuagag     2160

ggugacgacg auacuucgcg gauggaggag guagacuga                            2199


<210>  5578
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  5578
augccggagg agguccauca uggcgaggaa gagguggaga cguuugcguu ucaagcggaa       60

aucgcgcagu ugaugucgcu cauaaucaau acguuuuaua guaauaagga gauauuuuug      120

cgcgaacuca ucagcaaugc cucggaugcg uuagauaaaa uccgcuauga gucguugacc      180

gauccgagca aguuagauag cgggaaagaa cucaagaucg auauaauacc gaauccgcag      240

gagaggaccu ugacguuggu cgauacgggg aucgggauga ccaaggcgga uuugaucaau      300

aacuugggga ccaucgcgaa aucgggcacc aaggcguuua uggaagcguu gcaggccggg      360

gcggauaucu cgaugauagg gcaguuuggg gucggguuuu auucggccua uuugguggcg      420

gagaaagucg ucgucauaac caagcauaau gaugaugagc aguaugcgug ggagucgucg      480

gcggggggcu cguuuaccgu gcgcgccgau cauggggagc cgaucgggag gggcaccaag      540

gucauauugc auuugaaaga ggaucagacg gaguaucucg aggaaaggcg cgugaaagag      600

guggugaaga agcauucgca auuuauaggg uauccgauca cguuguauuu agagaaggaa      660

cgcgagaaag agaucucgga ugaugaagcg gaagaggaga agggggagaa ggaggaggag      720

gauaaggaug augaggagaa accgaaaaua gaggaugucg ggucggauga ggaggaugau      780

agcgggaaag auaaaaagaa gaagaccaag aagauaaagg aaaaguauau agaucaggag      840

gaauuaaaua agaccaagcc gauauggacg cgcaauccgg acgauauaac ccaggaggag      900

uauggcgagu uuuauaagag cuugaccaau gauugggaag aucauuuggc cgucaaacau      960

uuuucggucg aggggcaguu ggaguuucgc gccuuguugu uuauaccgcg ccgcgccccg     1020

uuugauuuau uugagaauaa aaagaagaag aauaauauca aauuguaugu gaggagggug     1080

uuuaucaugg auagcuguga ugaguuaaua ccggaguauu ugaauuuuau aagagggguc     1140

gucgauagug aggauuugcc guugaauaua ucgagggaga uguugcagca aucgaaaauc     1200

uuaaagguca uacgcaagaa uauagucaag aaauguuugg aguuguuuuc ggagcucgcc     1260

gaagacaagg agaauuauaa aaaguuuuau gaggcguuuu cgaaaaauuu gaaguuaggg     1320

auccaugagg auucgacgaa caggcgcagg uugucggagu uguugcgcua ucauaccucg     1380

caaucggggg augaaaugac cucguugagu gaguaugucu cgagaaugaa ggagacccag     1440

aaaagcaucu auuauauaac gggggaaucg aaagagcagg ucgccaauag cgccuuugug     1500

gagaggguca ggaaaagggg guuugaggug gucuauauga ccgaaccgau agaugaauau     1560

ugcguccagc aauugaagga guuugauggg aagucguugg ugagcgucac gaaggagggg     1620

uuggagcucc cggaggauga ggaggaaaaa aagaagaugg aggagagcaa ggcgaaguuu     1680

gaaaaucucu guaaauuaau gaaggaaaua uuggauaaga aagucgagaa agugaccaua     1740

agcaauagau uagucucgag cccguguugu auagugaccu cgaccuaugg guggaccgcc     1800

aauauggaga ggaucaugaa ggcccaggcg uugcgcgaua auagcacgau gggcuauaug     1860

auggcgaaaa agcauuugga gaucaauccg gaucauccga ucgucgagac cuugcgccag     1920

aaagcggagg ccgauaagaa ugauaaggcg gucaaggauu uggucguguu auuguuugag     1980

accgcguugu ugagcucggg guucagcuua gaagauccgc agacgcauuc gaaucgcaua     2040

uauaggauga ucaaauuggg guuagggauc gaugaagaug aggucgcggc cgaggaaccg     2100

aaugccgccg ugccggauga gauacccccg uuagagggcg augaagaugc cagccgcaug     2160

gaggaagugg auuga                                                      2175


<210>  5579
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  5579
augcgcgcgu ugugggucuu ggguuugugu ugugucuugu ugacauuugg gagcgugagg       60

gccgaugaug aaguggaugu agaugggacc guggaggaag auuuggggaa gucgagggag      120

gggucgagaa ccgacgauga agugguacaa agggaagagg aagccaucca auuggacggg      180

uugaaugcgu cgcaaaucag ggaauugaga gaaaaaucgg agaaauucgc guuucaggcg      240

gaggugaauc gcaugaugaa guugauuaua aauaguuugu auaagaacaa ggaaaucuuu      300

uuaagagagu ugauaaguaa ugcgucggac gcgcucgaca aaaucagguu gauaucguua      360

accgaugaga acgcgcucuc gggcaaugaa gaguugacgg ucaagaucaa augugauaaa      420

gaaaaaaauu uauugcacgu caccgauaca ggggucggga ugacgaggga ggaauuggug      480

aagaauuugg ggacgaucgc gaaaucgggg accucggaau uuuugaauaa gaugaccgaa      540

gcgcaagagg augggcaaag caccucggaa uugaucgggc aauuuggcgu cggcuuuuau      600

ucggccuuuu uggucgccga uaaagucauc gugaccucga agcauaauaa ugacacgcaa      660

cauauuuggg aaagcgauuc gaaugaguuc ucggucauag ccgaucccag agggaauacc      720

uuggggcgcg ggacgacgau aaccuugguc uugaaagagg aagccagcga uuauuuggag      780

uuagauacca uaaagaauuu ggucaaaaag uacucgcaau uuauuaauuu ucccaucuau      840

guguggucga gcaaaaccga gaccgucgaa gaaccuaugg aagaagaaga agccgcgaag      900

gaggaaaagg aggagagcga cgaugaggcc gccguggaag aggaggaaga ggaaaagaaa      960

ccgaaaacga aaaaggucga aaagacgguc ugggauuggg aguugaugaa cgauauuaag     1020

ccgaucuggc aaaggcccuc gaaggaggug gaagaggaug aauauaaggc guuuuauaaa     1080

ucguuuucga aagagucgga cgauccuaug gcguacaucc auuucaccgc ggagggggaa     1140

gucaccuuua agucgauauu guuugugccu accucggcgc cgcgcggguu guucgaugag     1200

uauggcucga aaaaaucgga uuauauaaag uuguauguaa ggagagucuu uauuacggau     1260

gauuuucaug auaugaugcc gaaauauuua aauuucguga aaggggucgu cgacagcgac     1320

gauuuaccgu ugaacgucuc gcgcgaaacc uugcaacaac auaaguuauu gaaagucauc     1380

aggaaaaaau uggugcgcaa gaccuuggau augauaaaaa aaaucgccga cgacaaauau     1440

aacgauaccu uuuggaagga auuugggaca aauauuaagu ugggggucau agaggaucau     1500

ucgaacagga cccgcuuggc caaguuguug cgcuuucaau cgucgcacca uccgaccgau     1560

aucaccucgu uagaucaaua cgucgagagg augaaagaga agcaagauaa gauauauuuu     1620

auggccggga guucgaggaa ggaagccgag ucgucgccgu ucgucgaaag guuguugaaa     1680

aaaggguacg aggugauaua ucucacggag ccggucgaug aguauuguau acaagcguug     1740

ccggaauuug augggaaacg cuuucaaaac guggccaaag agggggucaa auuugaugag     1800

ucggaaaaaa ccaaagaaag ccgcgaggcc guggaaaagg aauuugaacc guuauugaau     1860

uggaugaagg auaaggcauu gaaagauaaa aucgagaaag ccgucgucag ccaaagauua     1920

acggaaucgc cgugcgcguu gguggcaucg caauaugggu ggucggguaa uauggaacgc     1980

auaaugaaag cccaagcgua ucaaaccggg aaagauauau cgacgaauua uuaugcgucg     2040

caaaaaaaaa ccuuugagau aaauccgcgc caucccuuga uucgcgauau guugaggcgc     2100

auaaaagagg augaagacga uaaaacgguc uuggauuugg caguagucuu guuugagacc     2160

gcgaccuugc gcucggggua uuuauugccg gauaccaagg cguaugggga uaggauagag     2220

aggauguugc gcuugucguu gaauaucgau ccggacgcca aagucgagga agaaccggaa     2280

gaagaaccgg aggaaaccgc cgaagauacg acggaagaua ccgaacaaga ugaagacgaa     2340

gaaauggacg uagggaccga ugaggaagag gagacggcca aagagagcac ggccgagaaa     2400

gaugaguugu ga                                                         2412


<210>  5580
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  5580
auggcgaggg agcucagggc guuguuguug ugggggagga gguugaggcc guuguugagg       60

gcgccggccu uggcggccgu gccggggggg aagccgaucu uguguccgag gcgcaccacc      120

gcccaguugg ggccgaggag gaauccggcg uggagcuugc aagcggggag guuguuuagu      180

acccagacgg cggaggauaa ggaggagccg uugcauucga ucauaucguc gacggaaagu      240

guccaggggu cgacgaguaa gcaugaauuu caagcggaga cgaaaaaguu guuggauaua      300

gucgcgaggu cguuguauag ugagaaggag guguuuauaa gggaguugau aagcaaugcc      360

agugaugccu uggagaaguu gaggcauaag uuggucagcg augggcaggc cuugccggag      420

auggagaucc acuugcagac gaaugccgag aaggggacga ucaccaucca ggauaccggg      480

aucgggauga cccaagaaga guuggugagc aauuugggga ccaucgcgag gucggggucg      540

aaggcguuuu uggaugcguu gcagaaucag gcggaggcga guaguaagau aauagggcaa      600

uuuggggucg gguuuuacag ugcguuuaug gucgccgaua ggguggaggu cuacagcagg      660

agcgccgcgc cggggaguuu gggguaucag ugguugagug augggucggg ggucuuugag      720

aucgccgagg cgagcggggu gaggaccggg acgaagauaa uaauccauuu gaagucggau      780

uguaaggagu ucucgagcga ggcgagggug agggaugugg ugacgaagua cagcaacuuu      840

gugagcuucc cguuguacuu gaaugggcgc aggaugaaua ccuugcaggc gauauggaug      900

auggauccga aggaugugag ggaguggcaa cacgaggaau uuuauaggua ugucgcccag      960

gcccaugaua agccgaggua uacguugcau uauaagaccg augcgccguu gaauauaagg     1020

aguauauuuu auguccccga uaugaagccg ucgauguuug augucaguag ggaguugggg     1080

agcagcgucg ccuuguauag ccgcaaggug uugauccaga ccaaggcgac ggauauauug     1140

ccgaaguggu ugagguuuau acgcggggug guggauucgg aggauauacc guugaauuug     1200

agcagggagu uguugcagga gagugcgcuc auaaggaagu ugagggaugu cuugcagcaa     1260

agguugauca aguuuuuuau agaccagagu aaaaaggacg ccgagaagua ugcgaaguuu     1320

uuugaggauu auggguuguu uaugagagag gggauaguca ccgccacgga acaggaagug     1380

aaggaagaua ucgccaaguu guugcgcuau gaaaguucgg cguugccgag cgggcaguug     1440

accucguugu cggaguaugc gagcaggaug cgcgccggga cgaggaauau auauuauuug     1500

ugugcgccga auaggcauuu ggccgagcau agcccguauu augaagcgau gaagaaaaag     1560

gauacggagg uguuauuuug uuucgagcag uuugaugagu uaacguuguu gcauuugcgc     1620

gaauuugaua agaaaaaguu gauaucggug gaaaccgaua uaguggucga ucauuauaag     1680

gaggagaagu uugaagauag gucgccggcg gccgaguguu ugagcgagaa ggagacggag     1740

gaguugaugg cguggaugag aaauguguug gggagucgcg ucacgaaugu caaggugacc     1800

uugcgcuugg auacgcaucc ggcgauggug acggucuugg agaugggggc cgcgaggcau     1860

uuuuugagga ugcagcaguu ggccaagacc caagaagaga gggcgcaguu guugcagccg     1920

acguuggaga ucaauccgag gcaugcguug aucaaaaagu ugaaccaguu acgcgcgagu     1980

gaaccggggu uggcgcaguu guugguggau caaauauaug agaaugcgau gauagccgcc     2040

ggguuggucg augauccgag ggcgaugguc gggagguuga acgaguuguu ggugaaggcc     2100

uuggaaaggc acuga                                                      2115


<210>  5581
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  5581
auggguaaga ucucgucauu accgacgcag uuguucaagu gcugcuucug cgacuucuua       60

aagguaaaga ugcacacgau gucgaguucc cacuuauucu acuuggccuu augcuuguug      120

acguucaccu ccucggcgac cgcagggccg gagaccuugu gcggcgcgga guuaguagac      180

gcguuacagu ucgucugcgg ugaccgaggu uucuacuuca acaagccgac ggguuacggg      240

uccucgucgc gccgugcacc gcagacgggc aucguugacg aaugcugcuu ccguucuugc      300

gaccuccguc gcuuagagau guacugcgcg ccguugaagc cggcgaaguc ggcccguucg      360

guacgcgcgc agcggcacac ggacaugcca aagacgcaga aagaggucca cuuaaagaac      420

gcgucgcgug gaucggccgg caacaagaac uaccggaugu ga                         462


<210>  5582
<211>  543
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_000603.1__HsIGF2

<400>  5582
augggcauac ccauggguaa gucaauguug guguuauuaa ccuucuuagc cuucgccucg       60

ugcugcaucg cggccuaccg uccgucagag acccuaugcg gcggggagcu aguagacacg      120

cuacaguucg ugugcggcga ccggggguuc uacuucucgc gccccgcguc gcgcgugucc      180

cgccguucgc gcggcaucgu agaggagugc ugcuuccgau caugcgacuu ggccuuauua      240

gagaccuacu gcgccacccc ggccaagucg gagcgagacg ugucgacgcc gccgaccgug      300

uuaccggaca acuucccccg guaccccguc ggcaaguucu uccaguacga cacguggaag      360

cagucgacuc agagacuucg ucgcggguua ccggcguugu ugcgugcccg acgaggccac      420

gugcuagcca aggaguuaga ggcguuccgc gaggcgaagc ggcaccgccc guuaaucgcg      480

uuacccacuc aggaccccgc gcacggaggc gccccgcccg agauggcguc gaaccgaaag      540

uga                                                                    543


<210>  5583
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  5583
augaacucgu ucaguacguc ggcguucggc cccgucgcgu ucucguuagg uuuguuauug       60

gucuuaccgg cggcguuccc agcgcccguu ccaccgggug aggacucgaa ggacguugcg      120

gcgccccacc gacagcccuu gaccucgucc gagcguaucg acaagcagau ccgauacauc      180

uuagacggua uaagugcguu acgcaaggag acgugcaaca aaucgaacau gugcgagagu      240

ucgaaggagg cguuagccga gaacaaccuc aacuugccga agauggcgga gaaggacggg      300

ugcuuccaga guggguucaa cgaggagaca ugcuuaguaa agaucauaac gggccuccuu      360

gaguucgagg ucuaccucga guacuuacag aacagguucg agucaucgga ggagcaggca      420

cgcgcgguuc aaaugucgac gaagguauug auccaguucc uccagaagaa ggccaagaac      480

uuagacgcga ucacgacgcc ggacccgacu accaacgcga guuuguuaac uaaguuacag      540

gcgcagaacc agugguugca ggacaugacc acccacuuga ucuugcgguc guucaaggag      600

uucuugcaga guucuuuaag agcguuaagg cagauguga                             639


<210>  5584
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  5584
augccguuau ugugguuaag gggguucuug uuagcgucgu gcuggaucau cgugcguucg       60

ucgccgacgc ccgggucgga gggucacucg gccgcaccgg acugcccaag uugcgcacuu      120

gccgcguuac cgaaggacgu uccgaacucg cagccggaga ugguugaggc cgugaaaaag      180

cacauauuga acauguuaca ccuaaagaag cgaccggacg uaacgcagcc gguccccaaa      240

gcggcccuau uaaacgcuau acggaaguua cacguuggga agguaggcga gaacgguuac      300

guggagaucg aggacgacau cgggcgccgc gccgagauga acgaguuaau ggagcagacg      360

ucagagauca ucaccuucgc ggagucgggc acugcgcgua agacuuugca cuucgagauc      420

ucgaaggagg guucggacuu aucgguggua gagcgggccg aggugugguu auucuugaag      480

gugccgaagg cgaaccgaac gcgaaccaag gucaccaucc gauuguucca gcaacagaaa      540

cacccccagg ggaguuuaga caccggggag gaggccgagg agguaggucu caagggggag      600

cgauccgagc uccucuuauc ggagaaggug gucgacgcgc gaaagucuac guggcacgua      660

uucccggugu cgucgucgau ccagcgccua cuugaccagg gcaagaguuc guuggacguc      720

cgcauagcgu gcgagcagug ccaggagucg ggcgcgucuc uuguauuguu agggaagaag      780

aagaagaagg aggaggaggg ugaggggaag aagaaggggg gcggggaggg cggggcgggc      840

gcggacgagg agaaggagca gucucaccgg ccguucuuaa uguuacaagc gcgucaaucg      900

gaggaccacc cgcaccgacg acgccgacgu ggguuagagu gcgacggcaa ggugaacauc      960

ugcugcaaga agcaguucuu cguuucauuc aaggacaucg guuggaacga cuggauaaua     1020

gccccgucgg gguaccacgc gaacuacugc gagggcgagu gcccguccca caucgccggu     1080

acuucgggcu cgucguuauc guuccacagu acgguuauaa accauuaccg uaugcgugga     1140

cacucccccu ucgcgaacuu gaagaguugc ugcgugccga ccaaguugcg ucccaugucg     1200

augcuuuacu acgacgacgg ccagaacauu auaaagaagg acauccagaa caugaucguc     1260

gaggaaugcg gcugcaguug a                                               1281


<210>  5585
<211>  1224
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_002184.2__HsINHBB

<400>  5585
auggacgguu uaccgggacg agcuuugggu gcggcuuguu uguuauuguu ggcagcgggu       60

ugguuaggcc cggaagcgug gggaucgccg acaccucccc cuacuccggc ggcgccaccg      120

cccccgccac cgccgggguc gccaggcggg ucccaagaua cuugcacaag uugcgggggu      180

uuccgacgac ccgaggaauu gggacgcgua gacggugauu ucuuggaagc uguaaagcgu      240

cauaucuuau cgcguuuaca gaugcgaggg cgaccgaaca uaacccacgc cguaccgaag      300

gcggcgaugg uuaccgcguu acgaaaguua caugcuggga agguucguga ggacgggcgu      360

guagagaucc cccauuugga cgggcacgcc ucgccagggg ccgacgggca agagcgaguc      420

ucggagauaa uuaguuucgc ggagacugac ggguuagcgu cgucgagggu acguuuauac      480

uucuucauau cgaacgaggg uaaccaaaac uuguucguag uacaggcgag uuuaugguua      540

uaccuuaagc uauuaccaua cguuuuagag aaggggucgc gucgaaaagu aaggguaaag      600

guauacuucc aagagcaagg ucacggcgac cgauggaaca ugguagagaa gcggguugac      660

cuuaagcgaa guggauggca cacguucccg uuaacugagg caauacaggc auuauucgag      720

cguggagagc gccgcuuaaa cuuagacgua caaugcgacu cgugccagga guuggcaguc      780

gucccaguau ucguagaccc cggggaggag agucaucgac cguucguagu aguacaggcg      840

cgcuuaggug acucgcgaca ccgaauccgg aagcgugguu uagagugcga cgguaggacg      900

aacuugugcu gccgacagca guuuuuuaua gacuuuaggu ugaucgggug gaacgacugg      960

auaauugcgc cgacaggaua cuacgguaac uauugcgaag gaaguugccc ggcguacuua     1020

gcgggggugc cagguucggc aucgucguuc cacacugcgg uaguuaacca guaccgaaug     1080

cgaggauuga auccggggac aguaaacucg ugcugcaucc cgacgaaguu aaguacgaug     1140

ucgauguuau acuucgacga cgaguacaac auaguaaagc gcgacguccc gaacaugauc     1200

guagaagagu gcgguugcgc guga                                            1224


<210>  5586
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  5586
auggcguuga ggguccucuu auugaccgcc uugaccuuau gccauggguu uaauuuggau       60

acggagaacg ccaugacguu ucaggagaau gccagggggu uugggcagag cgucgugcag      120

uugcagggga gcagggucgu ggugggggcg ccgcaggaaa ucguggccgc caaucagagg      180

gggagcuugu aucaguguga uuauagcacg ggcagcugug agccgauacg cuuacaggug      240

ccgguggagg ccgugaauau gucguuaggg uugucguugg cggcgaccac gagcccgccg      300

caguugcucg ccugugggcc gacggugcac caaacgugua gcgagaauac guaugucaag      360

ggguuguguu ucuuguucgg caguaauuug aggcaacaac cgcagaaguu uccggaggcg      420

uugagggggu gcccccagga ggauucggau aucgcguucu ugaucgaugg gagugggagu      480

aucaucccgc augauuuuag gagaaugaaa gaguucguga gcaccgucau ggagcaguug      540

aaaaagagua agaccuuguu uaguuuaaug caguauucgg aagaauuucg cauacauuuu      600

acguuuaagg aauuucaaaa uaauccgaau ccgaggagcu uagucaagcc gaucacccag      660

uuguuggggc gcacccauac cgcgaccggg auacgcaaag uggucaggga guuguuuaau      720

aucaccaacg gggccaggaa gaaugcguuu aagauauugg ucgugaucac ggauggggag      780

aaguuuggcg auccgcucgg guaugaggau gucauaccgg aggccgaucg cgaagggguc      840

auaagguaug ugauaggggu cggcgaugcg uuuaggucgg agaagaguag gcaagaguug      900

aauaccaucg cgaguaagcc cccgagggau cauguguuuc aggugaauaa uuuugaggcg      960

uugaagacga uacagaauca guugagggaa aagaucuuug cgaucgaggg gacgcagacg     1020

gggucgaguu cgaguuuuga gcacgagaug agucaggagg gguuuucggc ggccauaacg     1080

aguaaugggc cguuguugag cacggugggg agcuaugauu gggccggggg gguguuuuug     1140

uauacgagua aagagaagag uaccuuuaua aauaugacgc gcguggacag cgauaugaau     1200

gaugccuacu ugggguaugc ggccgccaua aucuugagga aucgcgucca gagcuugguc     1260

cucggggcgc cgagguauca gcauauaggg uuggucgcca uguuuaggca gaauacgggc     1320

augugggagu cgaaugccaa ugugaaaggg acgcagauag gggccuauuu uggggccagc     1380

uuguguagcg ucgaugugga uagcaauggg ucgaccgacu uggucuugau aggggccccg     1440

cauuauuacg aacaaaccag gggggggcag gucagcgugu gcccguugcc gagggggagg     1500

gcgagguggc agugugaugc cgucuuguac ggggagcagg ggcagccgug ggggcgcuuu     1560

ggggcggccu ugacgguguu gggggaugug aauggggaua aguugacgga ugucgccaua     1620

ggggccccgg gggaagagga uaauaggggg gccgucuauu uguuucaugg gacgaguggg     1680

ucggggauaa gcccgaguca uagccagagg aucgcgggga gcaaguuaag uccgcgcuua     1740

caguauuuug gccagucguu gagugggggg caggauuuga ccauggaugg guuggucgac     1800

uuaaccgucg gggcccaggg ccacgucuug uuguugagga gucagccggu cuugagggug     1860

aaagccauaa uggaauuuaa cccgagagag guggccagga auguguuuga guguaaugau     1920

caggucguga aagggaagga ggcgggggag gugcgcgucu gcuuacaugu ccagaaaucg     1980

accagggaca gguuaaggga ggggcagaua caaagugucg ugacguauga uuuggcguug     2040

gauagugggc gcccgcauuc gagggcggug uuuaaugaga cgaagaacag cacgaggaga     2100

cagacgcaag ucuugggguu gacgcagacc ugugaaaccu ugaaguugca guuaccgaau     2160

ugcauagagg auccggugag cccgauaguc uugagguuga acuucaguuu gguggggacc     2220

ccguugagcg ccuuugggaa uuugaggccg guguuggcgg aggaugcgca gagguuguuu     2280

acggcguugu uuccguuuga gaaaaauugu gggaaugaua auaucugcca ggaugauuug     2340

ucgauaacgu uuagcuuuau gagcuuggau uguuuggucg ucggggggcc gagggaguuc     2400

aaugugaccg ugacgguccg caaugauggg gaagacaguu aucgcaccca ggucaccuuu     2460

uuuuuucccu uggauuugag cuauaggaag gugagcacgu ugcagaauca gaggagccag     2520

aggagcuggc gcuuggccug cgagagcgcg agcagcaccg aggucucggg ggcguuaaag     2580

agcacgaguu gcaguaucaa ucauccgaua uuuccggaaa auucggaggu gaccuuuaau     2640

aucaccuuug augucgauag caaggccagc uuggggaaua aguugcucuu aaaggcgaau     2700

gugacgucgg agaauaauau gccgcgcacc aauaagaccg aauuucaguu ggaguugccg     2760

gugaaauacg cggucuauau gguggugacg ucgcaugggg ucaguaccaa guauuugaau     2820

uucacggcgu cggagaauac cagucgcguc augcagcauc aguaucaagu caguaauuug     2880

gggcagaggu cguugccgau aaguuugguc uuuuuggucc cggugcgcuu gaaucaaacc     2940

gucaucuggg auaggccgca ggucaccuuu agcgagaauu ugaguaguac cugccauacc     3000

aaggagaggu ugccgucgca cagugauuuc uuggccgaau ugaggaaggc gccggucguc     3060

aauuguagca uagccgucug ucaaaggauc caaugugaua ucccguuuuu cggcauccaa     3120

gaggaauuua augccaccuu gaaggggaau uugucguuug auugguacau aaaaacgagc     3180

cacaaucauu uguugaucgu caguaccgcg gagauauugu uuaaugauuc gguguuuacc     3240

cucuuaccgg ggcagggggc cuuugucagg agccaaaccg agaccaaggu cgagccguuu     3300

gaggugccca aucccuugcc cuugauagug gggaguagug ucgggggcuu guuguuguug     3360

gcguugauaa ccgccgccuu auacaaauug ggguuuuuua aaaggcagua uaaggacaug     3420

augagugagg gggggccccc gggcgcggag ccgcaauga                            3459


<210>  5587
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  5587
auguuuaguu uaaaaaccuu gccguucuua uugcucuugc acguccaaau caguaaagcg       60

uucccgguca gcagcaagga aaagaacacc aagaccgucc aagauuauuu agagaaauuu      120

uaucagcucc cgucgaauca auaccaaagc acccgcaaaa acgggaccaa cgucauaguc      180

gagaaauuga aggagaugca aagguucuuc ggccucaacg ucaccggcaa accgaacgaa      240

gagaccuuag auaugaugaa gaaaccgagg ugcggggucc cggauucggg gggguucaug      300

cucacgccgg ggaauccgaa augggagagg accaaucuca cguaucgcau caggaauuac      360

acgccgcaau uaagcgaagc cgaagucgag cgcgccauaa aagacgcguu cgaguugugg      420

ucggucgcca gcccguugau auuuacgcgc auaagccaag gggaagccga cauaaauauc      480

gccuucuauc agcgcgacca uggggauaac agcccguucg acgggccgaa cgggauauug      540

gcccacgcgu uccaaccggg gcaggggauc gggggggacg cccacuucga cgcggaggag      600

accuggacga auacgagugc caacuauaau cucuucuugg ucgccgccca cgaguucggg      660

cacagccucg gcuuggccca uaguagcgau ccgggggcgc ucauguaccc gaauuacgcc      720

uuucgcgaga cgucgaauua uagcuugccg caggacgaua uagacgggau ccaagcgaua      780

uacggguuga gcucgaaucc gauacagccg accgggccgu cgaccccgaa gccgugcgau      840

ccgucgcuca ccuucgacgc cauaacgacc uugagggggg agaucuuguu uuucaaggau      900

cgcuauuuuu ggcgccgcca cccgcaauug cagcgcgugg agaugaacuu caucagcuug      960

uuuuggccga guuugccgac cgggauccaa gccgccuacg aggacuucga ucgcgauuug     1020

aucuuuuugu ucaaggggaa ucaguauugg gccuuaucgg gguacgacau cuuacagggg     1080

uacccgaaag acaucagcaa uuacggguuu ccgucgucgg ugcaggccau cgaugccgcc     1140

gucuuuuauc gcucgaagac cuauuuuuuc gucaacgauc aguuuuggcg cuacgacaau     1200

cagcgccagu uuauggaacc gggguacccg aagucgauca gcggggcguu cccggggauc     1260

gaaucgaagg ucgacgccgu cuuucaacag gagcacuuuu uucacguguu uucggggccg     1320

cgcuacuaug ccuucgacuu gaucgcccaa cgcgucacgc gcgucgcccg cgggaacaag     1380

ugguugaauu gccgcuacgg guga                                            1404


<210>  5588
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  5588
augucguuau ggcaaccuuu gguauuggua uuauuggucu uagggugcug cuucgcagcg       60

ccgcgucagc gacagucgac auuagucuug uucccgggug acuuacgaac caacuuaacu      120

gaucggcaau uagcugaaga guauuuauac agguacggcu acacgcgcgu agcggagaug      180

aggggggagu cuaagaguuu aggcccagca uuacucuugu ugcagaaaca guuaucguua      240

cccgaaacgg gggaauuaga cucggcgaca cucaaggcga ugcgcacucc ucguugcgga      300

guacccgacu ugggacgauu ucagacauuc gagggugauu ugaaguggca ccaccacaac      360

auaacguacu ggauccagaa cuacucugag gacuuaccuc gugcaguaau agacgacgcu      420

uucgcacgag cguucgcuuu auggucggcc guuacacccu ugacguuuac gcgagucuau      480

ucgcgcgacg ccgacauagu aauacaguuc gggguagccg agcacgguga cggcuaccca      540

uucgacggua aggacgguuu auuagcgcac gcguucccgc cggggccggg uauccagggc      600

gacgcgcacu ucgacgacga cgaauuaugg ucuuuaggga aagggguagu uguaccuacg      660

cguuucggua acgcggacgg ugccgcaugc cauuucccgu ucauauucga ggggcgauca      720

uauagugcgu gcacuacgga cggacggucg gacggguuac ccugguguuc gacuacugcg      780

aacuacgaca cggacgaccg auucgguuuc ugcccgucgg agcguuuaua cacgcaagac      840

gguaacgcgg acggcaagcc uugccaguuc ccuuucauau uccagggaca gucguacucg      900

gcaugcacaa ccgacgggcg gucggacggg uaccgguggu gcgcgacuac ggcgaacuac      960

gaucgcgaca aguuauucgg guucugccca acacgggcag acucuaccgu aaugggaggg     1020

aacagugccg gagaguugug cguauucccc uucacguucu ugggaaaaga guacucaaca     1080

ugcacuucgg aaggccgggg ugacggucga uuguggugcg ccacuacgag uaacuucgac     1140

ucggacaaaa agugggguuu cuguccugac cagggcuauu cguuauucuu aguagcagca     1200

cacgaguucg ggcacgcauu aggauuggac cacaguagug uacccgaagc auugauguau     1260

ccgauguacc gauuuacgga agguccgccg uuacacaagg acgacguaaa cgguauccga     1320

cacuuauacg gcccacggcc ggagccggaa ccgcgcccac cgaccacaac gacuccacag     1380

cccacugcac cgcccacagu auguccuacg gguccuccga caguacaccc gucggagcga     1440

ccgacggcag gucccacugg accgccgagu gcagggccga cggggccgcc gaccgcaggu     1500

ccgucgacgg cgacaacggu cccguuaucg cccguagacg acgcgugcaa cguuaacaua     1560

uucgacgcaa uagcagagau agguaaccag uuauacuuau ucaaggacgg caaguacugg     1620

cgcuuuucgg aggggcgagg aagucgaccc caggggccgu ucuuaaucgc ggacaagugg     1680

ccggcauuac cucgaaaguu agauucagua uucgaggagc gauuaaguaa gaaauuauuc     1740

uucuucucgg guaggcaagu auggguauau acgggugccu ccguauuagg gccccggagg     1800

cucgacaagu uggggcucgg ugcugacguc gcgcagguaa cgggugcuuu acgcucgggu     1860

cgaggaaaga uguuauuauu caguggucgc cgauuauggc guuucgacgu aaaggcacag     1920

auggucgacc cucgaucggc gucggagguc gaccguaugu ucccgggugu accguuagac     1980

acacacgacg uauuccagua ccgcgaaaag gcuuacuucu gccaggauag guucuacugg     2040

cgagucucgu cgaggucgga auuaaaucaa guagaccagg uaggguaugu cacguacgac     2100

aucuuacagu gcccggagga cuga                                            2124


<210>  5589
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  5589
augcacccgg gcguguuagc cgcguuuuug uuucucucgu ggacccacug cagagcguua       60

ccguugccgu cgggggggga cgaggacgac cucagcgaag aggauuugca auucgccgaa      120

agguauuuac gcagcuauua ucacccgacc aacuuggccg ggauauuaaa agaaaacgcc      180

gccucgagua ugaccgaacg cuugagggag augcaaaguu uuuuugggcu cgaagucacc      240

gggaaguugg augacaauac gcucgacgug augaagaaac cgcgcugugg cgucccggac      300

gucggggagu auaacgucuu uccgaggacc uugaagugga guaagaugaa ccucacguau      360

cgcaucguca acuauacgcc ggacaugacc cacagcgagg uggagaaagc cuuuaagaag      420

gcguuuaagg ucuggaguga cgucaccccg uuaaacuuca cgcgcuugca ugacgggauc      480

gccgauauaa ugauuagcuu cgggaucaaa gaacacgggg auuuuuaucc guucgacggc      540

ccgagcgggu uauuagccca cgccuucccg ccgggcccga acuacggggg ggacgcgcac      600

uucgacgacg acgagacgug gaccucgucg aguaaggggu auaaucucuu cuuggucgcc      660

gcccacgaau uugggcauag ucucggguug gaucauagua aagauccggg ggccuugaug      720

uucccgauau auacguauac ggggaagucg cauuucaugu ugccggacga ugacguccag      780

ggcauacaaa guuuguacgg gccgggggac gaggauccga auccgaagca cccgaagacc      840

ccggauaagu gcgauccgag ucucaguuug gacgcgauca cgucguugag gggggagacc      900

augauauuca aggaucgcuu uuuuuggagg uuacacccgc aacaagucga cgccgaauua      960

uuccucacca agagcuucug gccggaguug ccgaauagga ucgacgccgc cuacgaacau     1020

ccgagccacg auuugauauu uauauuucgc gggcgcaagu ucugggccuu gaacggguac     1080

gauaucuuag agggguaccc gaagaagauc agcgaguuag gguugccgaa ggaggucaaa     1140

aaaaucucgg ccgccgucca uuucgaagac accgggaaaa ccuuguuauu uagcgggaau     1200

caaguguggc gcuacgacga caccaaucac aucauggaca aggauuaccc ccgcuugauc     1260

gaggaggauu uuccggggau cggggacaag gucgacgccg uguacgaaaa gaacggguac     1320

auauacuucu uuaaugggcc gauccaauuc gaguauucga uauggucgaa uaggaucguc     1380

agggugaugc cggccaacag uauccucugg ugcuga                               1416


<210>  5590
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  5590
auggaaaccc cgaacaccac cgaagauuac gacaccacaa ccgaguucga cuacggcgac       60

gccacccccu gccaaaaagu caacgaacgc gccuucggcg cccaacuccu cccaccccuu      120

uacucccucg ucuucgucau cggccucguc ggcaauaucc ucguaguccu cguccucguc      180

caauacaaac gacucaaaaa caugaccucc aucuacuuac ucaacuuagc caucuccgac      240

cuccucuucc ucuucacccu ccccuucugg auagacuaca aacucaaaga cgacuggguc      300

uucggcgacg ccaugugcaa aauccucucg ggcuucuacu acacaggacu cuacuccgaa      360

aucuucuuca ucauccucuu aacuaucgac cgcuaccuag ccaucgucca cgccgucuuc      420

gcacuacgcg cccgcaccgu aaccuucggc gucaucaccu caaucaucau cugggcccuc      480

gccauccucg ccuccaugcc cggccucuac uucucaaaaa cccaauggga guucacacac      540

cacacaugcu cacuccacuu cccccacgaa uccuuacgcg aauggaaacu cuuccaagcc      600

cucaaacuca accuauucgg ccuaguccuc ccacuacucg ucaugaucau cugcuacaca      660

ggcaucauca aaauacuccu ccgccgcccc aacgaaaaga aauccaaagc aguccgccuc      720

aucuuuguca uaaugauaau cuucuuccua uucuggaccc ccuacaaccu caccauccuc      780

aucucaguau uccaagacuu ccucuucacc caugaaugcg aacaaucacg ccacuuagac      840

cucgccgucc aagucaccga ggucauugcc uacacccacu gcugcgucaa cccaguaauc      900

uacgccuucg ucggcgaacg cuuccgcaaa uaccuccguc aacuauucca ccgacgcguc      960

gccguacacc ucgucaaaug gcuccccuuc cuaucugucg accgauuaga acgcgucucc     1020

uccacaagcc caagcaccgg cgaacacgaa cucuccgccg gcuucuga                  1068


<210>  5591
<211>  636
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_002598.4__HsPDGFA

<400>  5591
augcgaacau uagcaugcuu guuguuauua gguugcgggu acuuagcgca cguguuagca       60

gaggaggcag agaucccgcg ugagguuauc gagcgcuugg cacgaucgca gauccacagu      120

auccgagacu uacagcgguu guuggagauc gacucagucg gcucggagga cucguuagac      180

acgaguuuac gagcgcacgg ggugcacgcc acgaagcacg uaccggagaa gcgcccguug      240

ccgauacguc gcaagcgauc gaucgaggag gcggugcccg cgguuugcaa gacgcgaacc      300

gucaucuacg agaucccacg aucgcaggua gacccuaccu cggcuaacuu cuuaauaugg      360

ccuccaugcg uagaggucaa gcguugcacg gggugcugca acacaucguc gguuaagugc      420

cagccgucgc gagugcacca ccguucggua aagguggcca agguugagua cguacgaaag      480

aagcccaagc uaaaggaggu ucagguucga uuggaggagc acuuagagug cgcuugcgcc      540

acgacgaguu ugaaccccga cuaccgugag gaggacacgg ggcgaccgcg cgagucgggc      600

aagaagcgaa agcgaaagcg guugaagccg acguga                                636


<210>  5592
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  5592
augaaccguu gcugggcccu uuucuugucg uuaugcugcu acuugcgcuu ggugucggcc       60

gagggugauc cgauaccgga ggagcuguac gagaugcuau cugaccacag uauaagguca      120

uucgacgacu ugcagcgauu auuacacggg gacccgggug aagaggacgg ggcggaguua      180

gacuuaaaca ugacgcgcuc gcacucgggu ggggaguugg agucguuagc gcgggggcgg      240

cgaucguuag ggucguugac gaucgcggag ccugcgauga ucgcggagug caagacgcgu      300

acggaggucu ucgagauauc gcgacguuua aucgaccgaa ccaacgcaaa cuucuuagua      360

uggcccccuu gcgucgaggu acagaggugc aguggaugcu gcaacaaccg aaacguccag      420

ugcaggccga cgcagguuca guugcguccg guacaagucc guaagaucga gaucguccgu      480

aagaagccga uauucaagaa ggcuacggua accuuagagg accaucucgc cugcaagugc      540

gagacugucg ccgcggcgag gccgguaacu cggucgcccg gugggaguca ggagcagcgu      600

gcgaagacgc cgcagacgcg aguuaccaua aggaccguac gugugcgucg uccgccgaaa      660

ggaaagcacc gaaaguucaa gcacacgcac gacaagacug ccuuaaagga gacguuaggu      720

gccuga                                                                 726


<210>  5593
<211>  1038
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_057289.1__HsPDGFC

<400>  5593
augucguuau ucggcuuguu auuauugacg agugcguuag cagggcagcg gcaagguaca       60

caggcagagu cgaaccucuc gucgaaguuc caguucucgu cgaacaagga gcagaacggu      120

gugcaggacc cacagcacga gcguaucauc acgguuucga caaacggguc gauacacucg      180

ccgcguuucc cacacacgua cccgcgaaac acuguguuag ucuggcgucu cguugccguc      240

gaggagaacg uuuggaucca guuaacuuuc gacgagaggu ucgguuuaga ggacccggag      300

gacgacaucu gcaaguacga cuucguugag guagaggagc cuucagacgg uacgaucuug      360

ggacgauggu gcgggucggg gaccguuccc gggaagcaga uaucgaaggg gaaccagaua      420

cgaauccgau ucgucucgga cgaguacuuc ccgucggagc cggguuucug cauacacuac      480

aacauaguaa ugccgcaguu cacggaggcc guuucgccgu cugucuuacc gcccucggcg      540

uuaccguuag acuuacucaa caacgcgauc acggcguucu cuacguuaga ggacuuaaua      600

cguuacuuag agccggagcg auggcaauua gacuuggagg acuuguaccg ccccaccugg      660

caguuacucg guaaggcauu cguauucggg cgaaagaguc gaguaguaga cuuaaauuua      720

uuaaccgagg agguucgacu auacucuugc acuccccgca acuucucggu uucgauccga      780

gaggagcuua agcgcacgga cacgauauuc uggccggggu gcuuauuggu caagaggugc      840

ggggguaacu gcgcgugcug ccuucacaac ugcaacgagu gccagugcgu gccgucgaag      900

gucacaaaga aguaccacga ggucuuacaa cuucgcccca agacgggcgu gcgagguuua      960

cacaagaguc uaacugacgu agcgcucgag caccacgagg agugcgacug cgucugcagg     1020

gggucgaccg ggggguga                                                   1038


<210>  5594
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  5594
augcaccgac uaaucuucgu auacaccuug auaugcgcca acuucugcuc cugccgagac       60

acgucggcca cuccccaguc ggcuaguaua aaggcccuuc guaacgcgaa cuugcgucgg      120

gacgaccuuu acaggaggga cgagacuauc caggucaagg gcaacggaua cguccaaucg      180

ccccgguucc ccaacaguua cccgcggaac uuacuuuuga ccuggcguuu acacucgcag      240

gagaacacga ggauccaauu aguuuucgac aaccaguucg gccucgagga ggccgagaac      300

gacauaugcc gauacgacuu cguagaggua gaggacauca gugagaccuc gacgauaauc      360

agggggcggu ggugcggcca caaggaggua cccccucgaa ucaagagucg aaccaaccag      420

aucaagauaa ccuucaaguc ggacgacuac uucguagcaa agccgggguu caagauauac      480

uacucgcucu uagaggacuu ccagccggcg gccgcgucgg agacaaacug ggagucggua      540

acgucgucga uaucgggugu gucguacaac ucacccucgg ucaccgaccc gaccuugaua      600

gccgacgcgu uagacaagaa gaucgccgag uucgacacgg uagaggacuu guugaaguac      660

uucaacccgg agucguggca ggaggacuua gagaacaugu acuuagacac gccgagguac      720

agggggcggu cguaccacga ccgcaagucg aagguggacu uagaccgacu uaacgacgac      780

gcgaagcgau acucgugcac accucgaaac uacaguguaa acaucaggga ggaguuaaag      840

uuagccaacg ucguauucuu cccgcggugc uuauuaguuc agcguugcgg gggcaacugc      900

gguugcggga cggugaacug gcgaucuugc acgugcaacu cggguaagac cguaaagaag      960

uaccacgagg uccuucaguu cgagcccggg cacauaaagc gucgcggccg ugcgaagacc     1020

auggcgcucg uggacauuca acucgaccac cacgagcguu gcgacugcau cugcucgucg     1080

cgaccuccgc guuga                                                      1095


<210>  5595
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  5595
augguaacgc acucgaaguu cccggcggcg gguaugagua ggccguuaga cacaucgcuu       60

cguuuaaaga cauucucguc gaagagugaa uaccagcucg uugucaacgc gguccggaag      120

uugcaagaau cagguuucua uuggucggcg guaacggggg gggaggcaaa uuuauuauug      180

ucggcggagc cagcggggac auucuuaauc cgugacucgu cugaccagcg gcacuuuuuu      240

acauuaucag ugaagacaca aucggguacg aagaaccuuc gaauacagug cgagggcgga      300

aguuucucgu ugcagaguga cccgcgaucu acacagccgg ucccucgauu cgacugcgua      360

uuaaaguugg uucaccauua caugccccca ccgggggcuc cgaguuuccc gucaccgccg      420

acggagccga guucggaggu accggagcag ccaucggcgc agccuuuacc ggguucgccg      480

ccucgacgcg cguacuacau auacucgggg ggugaaaaga uuccacucgu auuaucgagg      540

ccuuuaucgu cgaacguagc gacacuccaa cacuugugcc gcaagaccgu uaacggacau      600

uuagacucgu acgagaaggu cacgcaacuc ccaggcccga ucagggaguu cuuggaccag      660

uacgacgcuc cauuauga                                                    678


<210>  5596
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  5596
auggugccga gcgccgggca auuggcguua uuugccuuag ggaucguccu cgccgccugu       60

caagcgcucg aaaauucgac cagucccuua ucggccgauc ccccggucgc cgccgccguc      120

gucagucacu ucaacgauug uccggacagu cauacccaau uuuguuuuca cgggacgugu      180

cgcuuccucg uccaagaaga uaaaccggcc ugcguguguc acagcggcua ugucggggcc      240

aggugcgaac acgccgauuu guuagcgguc gucgccgcgu cgcaaaaaaa acaagcgaua      300

acggcgcucg ucgucgugag uauagucgcg uuagccgugu ugauaauaac cugcgucuua      360

auccauuguu gucaagugag gaagcauugc gaauggugua gagcguugau auguagacau      420

gaaaaaccgu cggcguuguu aaaagggcgc acggccuguu gucauagcga gaccgucgug      480

uga                                                                    483


<210>  5597
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  5597
augcccccgu cugguuuacg auuauuaccc uuauuguuac ccuuauugug guuauuagua       60

uugacccccg ggcgaccggc cgccggcuua aguacgugca agaccaucga cauggaguua      120

guaaagcgga agcgaauaga ggcgauacga gggcagaucu uaucgaaguu acgauuagcc      180

aguccgcccu cgcagggcga gguaccgccc gggcccuugc ccgaggccgu auuagcguua      240

uacaacagua cccgagaccg aguagcgggu gagucugcgg agcccgagcc cgagcccgag      300

gccgacuacu acgccaagga gguaacacga guauugaugg uagagaccca caacgagauc      360

uacgacaagu ucaagcagag uacgcacucu aucuacaugu ucuucaacac gagugaguua      420

cgagaggcgg uucccgagcc cguauuauua agucgagcgg aguuacgauu auugcgauua      480

aaguuaaagg uagagcagca cguagaguua uaccagaagu acaguaacaa cucuuggcga      540

uacuuaucaa accguuuauu agcgccgucu gacagucccg agugguuauc uuucgacgua      600

acggggguag uacgacagug guuaagucgu gggggcgaga uagagggguu ccgauuguca      660

gcgcacugca guugcgacuc ucgggacaac acguugcagg uagacaucaa cggcuucacg      720

acggggcgac gaggcgacuu agccaccaua cacggcauga accgacccuu cuuauuauua      780

auggccacgc ccuuagagcg ugcgcagcac uuacagucua gucgacaccg acgagccuua      840

gacaccaacu acugcuucag uucgaccgag aagaacugcu gcguacgaca guuauacauc      900

gacuuccgaa aggacuuagg guggaagugg auacacgagc cgaagggcua ccacgcgaac      960

uucugcuuag ggcccugccc cuacaucugg ucguuagaca cgcaguacag uaagguauua     1020

gccuuauaca accagcacaa ccccggcgcc ucggcggccc cgugcugcgu accgcaggcg     1080

uuggagcccu uacccauagu auacuacgua ggccguaagc cgaagguaga gcaguuaagu     1140

aacaugauag uacgaucgug caagugcagu uga                                  1173


<210>  5598
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  5598
augcacuacu gcguauuauc ugcguucuug auauuacacu uaguuaccgu ggcauugagu       60

uuauccacuu gcaguacguu agacauggac caguucaugc gaaagcgaau agaggcuaua      120

aggggucaga uuuugucgaa gcucaaguua acgucuccuc cggaggacua ccccgagccg      180

gaagagguac cgccggaggu aaucaguaua uacaacucga cgcgagaccu uuuacaggaa      240

aaggcaucgc gacgcgcagc ggcgugcgag agggagcguu cggacgagga guacuacgcg      300

aaggaaguau acaagaucga caugccuccg uucuucccgu cggagaacgc gaucccaccu      360

acguucuauc gaccguacuu ccgcaucguc agguucgacg uaagugcgau ggagaagaac      420

gccucuaacu uaguaaaggc ggaguuucga guauucaggu uacagaaccc gaaggcgcga      480

guucccgagc agaggaucga guuauaccag aucuuaaaga guaaggaccu uacuucgccu      540

acgcaacgau acauagacag uaagguagua aagacgcgag ccgagggaga gugguuaucg      600

uucgacguca cggacgcggu ccacgagugg uuacaccaca aggaccgcaa ccuuggcuuc      660

aagaucaguc uccacugccc gugcugcaca uucgucccuu cgaacaacua uauaauaccg      720

aacaagucgg aggaguuaga ggcucguuuc gcgggaaucg acgggacguc gacguacacg      780

ucgggagacc agaagacgau caagucgacg cgaaagaaga acucgggaaa gacaccgcac      840

uuguuauuaa uguuguuacc gucguacagg uuagagucgc agcagacgaa ccgccgaaag      900

aagcgagcgc uagacgcagc guacuguuuc cgaaacguac aagacaacug cuguuuaagg      960

cccuuauaca ucgacuucaa gcgcgacuug gguuggaagu ggauccacga gccuaagggu     1020

uauaacgcaa acuucugcgc aggcgcgugc cccuaccucu ggucgucgga cacccaacac     1080

agucgagugu uaucucuuua caacacgauc aaccccgagg cgagugccuc gccgugcugc     1140

gucucgcagg acuuggagcc auuaacgauc uuguacuaca ucgguaagac gccuaagauc     1200

gagcaguuau cgaacaugau agucaaaagu ugcaagugcu cauga                     1245


<210>  5599
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  5599
augaagaugc acuugcagag ggcguuggua guauuagcgu uauugaacuu cgcgacggua       60

ucguuaaguu uaucgacaug cacgacguug gacuucggcc acaucaagaa gaagcgcgua      120

gaggcgauac ggggucagau auuaaguaag uuacgcuuga cgucgccgcc ggagccgacg      180

guaaugacac acguaccgua ccagguauua gcguuauaca acaguacgag ggaguuguua      240

gaggagaugc acggugagcg cgaggagggu ugcacgcagg agaacacgga gucggaguac      300

uacgcgaagg agauacacaa guucgacaug auacaggguu uagcggagca caacgaguug      360

gcgguaugcc ccaaggggau aacgaguaag gucuucaggu ucaacguauc gaguguagag      420

aagaaccgca cgaacuuauu cagggcggag uuccgaguau uaaggguccc gaacccgucg      480

aguaagcgaa acgagcagag gauagaguua uuccagauau uacgccccga cgagcacaua      540

gcgaagcagc gguacauagg ggguaagaac uuacccacgc gcgguacggc ugagugguug      600

ucguucgacg uaacagacac gguaagggag ugguuauuac gcagggagag uaacuugggc      660

uuagagauau cgauacacug cccuugccac acguuccagc cgaacgggga cauauuagag      720

aacauacacg agguaaugga gauaaaguuc aaggguguag acaacgagga cgaccacggg      780

cgaggggacu uggggagguu aaagaagcag aaggaccacc acaaccccca cuuaauauug      840

augaugauac cgccgcaccg auuagacaac cccggucagg gggggcagcg aaagaagagg      900

gcguuagaca cgaacuacug cuuccgaaac uuggaggaga acugcugcgu aaggccguua      960

uacauagacu uccgccagga cuuagggugg aaguggguac acgagccgaa ggguuacuac     1020

gcuaacuucu gcaguggucc gugccccuac uugaggucgg cagacacaac gcacaguacg     1080

guauuagguu uauacaacac guugaacccg gaggcgucgg cuaguccgug cugcguaccg     1140

caggacuuag agcccuuaac aauauuguac uacguaggga gaacgccgaa gguagagcag     1200

uuaucgaaca ugguaguaaa gucgugcaag ugcaguuga                            1239


<210>  5600
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  5600
auggccccgg uggcggucug ggcggcuuua gcgguagggc uugagcuuug ggcggccgcg       60

cacgcguuac cggcgcaggu cgcguucacg cccuacgcuc ccgagccggg uucaacgugc      120

agguugcgcg aguacuacga ccaaacugcg cagaugugcu gcucgaagug cuccccggga      180

cagcacgcga agguauucug caccaaaaca ucagacacgg ugugcgacuc gugcgaggac      240

ucgacuuaca cgcaauuaug gaacugggug cccgagugcc ucucgugcgg aucgcgaugc      300

ucgucagacc aaguagagac ccaggccugc acgcgcgagc aaaaccggau cugcacgugc      360

cgcccgggcu gguacugcgc cuugucgaag caggaggguu gccgacucug cgcgccccuc      420

cgaaagugcc ggccggguuu cgggguagcg cgaccuggga cggagacguc ggacguaguc      480

ugcaagccgu gcgcgcccgg aacauucucu aacacgacau cgucuaccga caucugccgc      540

ccgcaccaga ucugcaacgu cguugcaauc ccggggaacg cgaguaugga cgcgguaugc      600

acaucgacgu cgccgacgcg cucaauggcg ccgggcgccg ugcaccuucc gcagcccgua      660

ucgacgcggu cgcagcacac ccaaccgacg ccggagccgu cgaccgcgcc gucgacuucg      720

uuccuuuuac ccauggggcc cucgccgccc gcggagggcu cgaccgguga cuucgcguug      780

ccgguagggu uaaucguggg cgucacggcg uuaggguugu uaaucaucgg cgucguaaac      840

ugcgugauaa ugacgcaggu aaagaagaag ccgcugugcu ugcagcgaga ggcgaaggug      900

ccgcacuuac cggccgacaa ggcccguggc acgcaggguc ccgagcagca gcacuuauua      960

auuaccgcgc cgucgucgag uucgaguucg uuggagucga gcgcaucggc ccuagacagg     1020

cgagccccca cgcgaaacca gccgcaggcg ccgggugugg aggcgucugg ggccggcgag     1080

gcccgugccu cgaccggauc gucggacucg ucgccgggcg gacacgguac acagguaaac     1140

guaacuugca ucguuaacgu augcucgucg ucggaccacu cgagucagug cucgagucag     1200

gcgucgucga cgauggggga cacugacucg ucgcccucag agaguccuaa ggacgagcag     1260

gucccguucu cgaaggagga gugcgccuuc cguagucaac ucgagacacc ggagacgcuc     1320

cucggaucaa cggaggagaa gccguuaccc uuaggcguuc cggacgcggg gaugaagccg     1380

ucguga                                                                1386


<210>  5601
<211>  513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_002623.2__HsPGF

<400>  5601
augcccguaa ugcgcuuauu uccauguuuc uugcaguuau uagcgggcuu ggccuuaccc       60

gcaguaccac cgcaacaaug ggcucucucg gcagggaacg guaguucgga aguugagguc      120

gucccguucc aggaggucug gggucgaagu uacugcaggg cccuugagcg ccucguggac      180

guaguaagug aguauccgag ugagguagag cauauguucu cgccuaguug cguuucuuua      240

uugaggugua cagguugcug cggugacgag aacuuacacu gcguacccgu agagaccgcc      300

aacguaacua ugcaauuauu gaagauucga ucgggagacc guccaucgua cguagaguua      360

accuuuaguc agcauguccg uugcgagugc cguccgcuuc gcgagaaaau gaagcccgag      420

cgucgaaggc cuaaagggcg cgggaagcgg cgcagggaga aacagcgacc uacggacugu      480

cacuugugcg gggacgcggu cccgcgacgc uga                                   513


<210>  5602
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001020537.2__HsVEGFA

<400>  5602
augaccgacc gccagaccga cacggccccc ucgccguccu accaccucuu acccggccgg       60

cgccggaccg uggacgccgc ggccucgcgc gggcagggcc ccgagcccgc ccccgggggc      120

ggggucgagg gcgugggcgc ccgcggggug gccuuaaagu uauucgucca gcucuuaggc      180

ugcucccggu ucgggggcgc gguggugcgg gccggggagg ccgagcccuc gggcgccgcg      240

cgcuccgccu cguccggccg ggaggagccc cagcccgagg agggggagga ggaggaggag      300

aaggaggagg agcgcggccc gcaguggcgg uuaggggccc gcaagcccgg cucguggacc      360

ggcgaggccg ccgucugcgc ggacuccgcc cccgccgccc gggccccgca ggcgcucgcc      420

cgcgccucgg ggcggggcgg gcgcguggcc cggcgcggcg ccgaggaguc cgggccgccc      480

cacucgcccu cccggcgcgg cucggcgucc cgggccggcc ccgggcgcgc cucggagacc      540

augaacuucu uauuauccug ggugcacugg ucgcucgccu uauuacucua cuuacaccac      600

gccaaguggu cccaggcggc cccgauggcc gagggcgggg gccagaacca ccacgagguc      660

gugaaguuca uggacgugua ccagcgcucg uacugccacc ccaucgagac guuagucgac      720

aucuuccagg aguaccccga cgagaucgag uacaucuuca agcccucgug cgugccgcuc      780

augcggugcg ggggcugcug caacgacgag ggcuuagagu gcgugcccac cgaggagucc      840

aacaucacca ugcagaucau gcgcaucaag ccccaccagg ggcagcacau cggcgagaug      900

ucguucuuac agcacaacaa gugcgagugc cggcccaaga aggaccgcgc ccggcaggag      960

aagaaguccg uccgcgggaa gggcaagggg cagaagcgga agcgcaagaa gucccgguac     1020

aagucguggu cgguguacgu gggcgcgcgc ugcugccuca ugccgugguc cuuacccggc     1080

ccccaccccu gcgggccgug cucggagcgg cgcaagcacu uauucgucca ggacccgcag     1140

acgugcaagu gcucgugcaa gaacacggac ucgcggugca aggcgcgcca gcucgaguua     1200

aacgagcgga cgugccgcug cgacaagccg cggcgcuga                            1239


<210>  5603
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  5603
augaacuucu uauugucgug gguccacugg aguuuagcgu uauuguuaua cuuacaccac       60

gcgaaguggu cgcaagcagc gccgauggcg gaggggggug gucaaaacca ccacgaggua      120

guaaaguuca uggacgugua ccagaggucg uacugccacc cgauagagac guugguagac      180

auauuccaag aguacccgga cgagaucgag uacaucuuca agccgucgug cguaccguua      240

augcgcugcg gugguugcug caacgacgag gguuuagagu gcgucccuac ggaggagagu      300

aacaucacua ugcagauaau gaggauuaag ccgcaucaag ggcagcacau aggggagaug      360

ucguucuugc agcauaacaa gugcgagugc cgaccgaaga aggaccgagc gcgacaggag      420

aagaagagug uaagggguaa agggaagggu caaaagcgca agaggaaaaa gagucgauac      480

aagucguggu cgguauacgu cggggccagg ugcugcuuaa ugccgugguc guuaccaggg      540

ccgcacccgu gcgggccgug cucggagcgc aggaagcacu uauucguaca ggacccacag      600

acgugcaagu gcaguugcaa gaacacggac ucgcguugca aggcacgaca guuagaguua      660

aacgagcgaa cgugccggug cgacaagccu cgaagguga                             699


<210>  5604
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  5604
augucgccgu uauugaggag guuauuauug gcggccuugu uacaauuagc gccggcgcaa       60

gcgccgguga gucaaccgga cgcgccgggg caucaacgca aggucgucag cuggaucgac      120

gucuacacca gggccacgug ucaaccgaga gaagucgucg ucccgcucac cgucgaauug      180

auggggacgg ucgcgaagca auuagucccg ucguguguca ccguccaaag gugcgggggg      240

uguuguccgg augacggguu agaaugcguc ccgaccggcc aacaucaggu gagaaugcaa      300

auauugauga uaagauaucc cucgucgcaa uuaggcgaaa ugaguuuaga ggagcauucg      360

caaugcgagu gucgcccgaa gaagaaagau ucggccguca aaccggaucg cgccgcgacc      420

ccgcaucaua ggccgcaacc gaggagcguc cccggguggg auagcgcgcc gggggccccg      480

aguccggccg auauaacgca cccgaccccg gcgccggggc cgagcgcgca ugccgccccg      540

ucgacgacgu cggcguuaac gccggggccg gcggccgcgg ccgcggaugc ggccgccagu      600

agugucgcga aagggggcgc cuga                                             624


<210>  5605
<211>  1260
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_005420.1__HsVEGFC

<400>  5605
augcaccucu uaggguucuu cagcgucgcc ugcuccuuac uggcggcggc ccuccugccc       60

gggccgcgcg aggccccggc ggcggcggcg gcguucgaga gcggccugga ccucuccgac      120

gccgagccgg acgcggggga ggcgaccgcc uacgccucga aggacuuaga ggagcagcug      180

cgguccguca gcuccgugga cgagcucaug accgugcugu accccgagua cuggaagaug      240

uacaagugcc aguugcgcaa gggcgggugg cagcacaacc gggagcaggc gaaccucaac      300

agccgcacgg aggagaccau caaguucgcg gccgcccacu acaacaccga gauccucaag      360

uccaucgaca acgaguggcg gaagacccag ugcaugccgc gcgaagucug caucgacguc      420

ggcaaagagu ucggcguggc cacgaauacg uuuuucaagc cgcccugcgu caguguguau      480

cggugcgggg gcuguuguaa cuccgaaggg uuacaaugua ugaauacguc gaccucguau      540

uuaucgaaaa cgcuguucga gaucaccguc cccuuguccc aggggccgaa gcccgucacc      600

auaucguucg cgaaccauac cucgugucgc uguaugagca aguuagacgu guaucgccag      660

gugcacucga ucauccggcg gaguuuaccc gcgacguugc cccaaugcca agccgccaau      720

aaaacguguc cgacgaacua uauguggaac aaccauauau gucgcuguuu agcccaagag      780

gacuucaugu ucaguuccga cgccggggac gauagcaccg acggcuuuca cgauauaugc      840

ggccccaaua aagaauuaga cgaggaaacg ugccaaugcg ucugucgggc gggguugcgc      900

cccgcgucgu gcggcccgca uaaggagcuc gaucggaaua gcugucaaug cgugugcaag      960

aauaaguugu uuccgucgca gugcggggcg aaucgcgagu ucgacgagaa uacgugucaa     1020

ugcgugugca agcggacgug uccgcgcaac cagccguuga accccggcaa gugcgcgugc     1080

gagugcaccg agucgccgca aaagugucuc cugaagggca agaaauuuca ucaucagacc     1140

uguucgugcu aucggcgccc cugcaccaau cggcaaaaag ccugcgaacc cggguucagc     1200

uacuccgagg aggucugccg cugcgugccc agcuacugga agcgcccgca gaugucguga     1260


<210>  5606
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt10) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  5606
auguacaggg aaugggucgu agucaacguc uucaugaugu uauacguaca auuaguacaa       60

gguucgucga acgagcacgg uccggucaag cguucgucgc aaucgacguu agagcguucg      120

gagcagcaga uacgagcggc gucgucguua gaggaguugc uacggauaac gcacucggag      180

gacuggaagu uauggcgaug ucgauuacgc uuaaagucgu ucacaucgau ggacucgagg      240

ucggcuucgc accgcucgac gcgguucgcc gcgacauucu acgacauaga gacguuaaag      300

gucaucgacg aggaguggca gcgcacgcag ugcucgccga gggagacuug cgucgagguc      360

gcgucagaau uggguaaguc gacuaacacg uuuuucaagc cuccgugcgu uaacgucuuc      420

cguugcgggg guugcugcaa cgaggagucg uuaaucugca ugaacacaag uacgucauac      480

aucucgaagc aauuauucga gaucucgguc ccauuaaccu cggucccgga guuggugccg      540

guaaagguag cgaaccacac ggggugcaag ugcuuaccga cggcuccgcg acacccguac      600

aguauaauac gacggucgau acagauuccc gaggaggacc gaugcaguca cucgaagaag      660

cuaugcccaa ucgacaugcu cugggacagu aacaagugca agugcguauu acaggaggag      720

aaccccuugg cggggacgga ggaccacucg cacuugcagg agccggcguu gugcggaccg      780

cacaugaugu ucgacgagga ccggugcgag ugcguaugca agacuccgug cccgaaggac      840

uugauucagc acccuaagaa cugcucgugc uucgaaugca aggagucguu agagacgugc      900

ugccagaagc acaaguuguu ccacccggau acaugcaguu gcgaggaccg augcccguuc      960

cacacacgac ccugcgcguc ggguaagacg gcuugcgcga agcacugccg auucccuaag     1020

gagaagcgag cggcacaggg uccgcacucu cguaagaacc cguga                     1065


<210>  5607
<211>  648
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified protein sequence (opt10) from Homo 
       sapiens__NP_002119.1__HsHMGB1

<400>  5607
auggguaaag gugacccgaa aaagccacgc gguaagauga guucguaugc guucuucguc       60

caaacgugcc gagaggaaca caagaaaaag cacccggacg cgucgguaaa cuucucggag      120

uucucaaaaa agugcuccga acgcuggaag acgaugucgg cgaaagagaa agguaaauuu      180

gaagauaugg cgaaagcgga caaggcgcgc uacgagaggg agaugaagac auauauaccg      240

ccgaagggug agaccaagaa aaaguucaag gacccgaacg cgccgaagcg gccgccgucu      300

gcguuuuucc uuuucuguuc ggaguaccgc ccgaagauaa agggagagca cccgggccuu      360

ucgauaggcg acguagcgaa aaaguugggu gaaaugugga auaacacggc ggcggacgau      420

aaacagccau augaaaagaa agcagcgaag cucaaggaaa aguacgagaa agauaucgcg      480

gcauaucgag caaaagguaa accggacgcg gcgaagaaag guguaguaaa agcagaaaag      540

ucgaagaaaa agaaagagga agaggaagau gaagaggacg aggaagauga agaggaagag      600

gaagaugaag aggacgagga cgaggaagag gacgaugacg augaauga                   648


<210>  5608
<211>  847
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt10)

<400>  5608
gggagaaagc uuaccaugga cuccgacgaa accggcuucg aacacucagg ccucuggguc       60

uccguacuag ccggccuccu ccucggcgcc ugccaagccc accccauccc cgacuccuca      120

ccccuccuac aauucggcgg ccaaguccgc caacgcuacc uauacaccga cgacgcccaa      180

caaaccgaag cccaccucga aauccgcgaa gacggcaccg ucggcggcgc cgccgaccaa      240

ucccccgaau cccuacuaca acucaaagcc cucaaaccug gagucaucca aauacucggc      300

gucaaaaccu cccgcuuccu cugccaacgc cccgacggag cccucuacgg cucccuccac      360

uucgacccag aagccugcuc uuuccgagaa cuccucuuag aagacggcua caacgucuac      420

caaucugaag cccacggccu cccccuucac cuccccggaa acaaaucacc ccaccgcgac      480

cccgcacccc gcggcccagc cagauuccuc ccccuccccg gccucccacc agcccucccc      540

gaaccacccg gcauccucgc accccaacca cccgacgucg gcuccuccga cccccucuca      600

auggucggcc ccucccaagg ccgcuccccc ucauacgccu caugaggacu aguuauaaga      660

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      840

cagaauu                                                                847


<210>  5609
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt10)

<400>  5609
gggagaaagc uuaccaugca uucguucccg ccguuauuau uauuauuauu uugggggguc       60

gucagccauu cguuuccggc caccuuggag acccaggaac aggacgucga ucucgugcaa      120

aaguauuuag agaaguauua uaauuuaaaa aacgacggcc gccaggucga gaaaagacgc      180

aacucggggc cggucgucga gaagcucaaa cagaugcaag aguuuuucgg cuuaaagguc      240

accggcaagc cggacgccga gacguuaaaa gucaugaaac aaccgcgcug cggggucccg      300

gacgucgccc aauucguguu gaccgaaggc aauccgaggu gggaacagac ccacuuaacg      360

uaucgcaucg agaacuauac cccggaccuc ccgcgcgccg acgucgauca cgcgaucgaa      420

aaggcguuuc aguugugguc gaacgugacc ccguuaaccu uuacgaaagu gagcgaaggg      480

caggccgaua uaaugaucag cuucgugcgc ggggaccaca gagauaauag cccguucgac      540

gggccggggg ggaacuuggc ccacgccuuc cagccggggc cggggaucgg gggcgacgcc      600

cacuucgacg aggacgagcg cuggacgaau aacuuucgcg aauauaaucu ccacaggguc      660

gccgcccacg aguuggggca cagcuugggg uugagucaca gcaccgacau aggcgcccuc      720

auguauccgu cguauacguu uucgggggac guccaauugg cccaagacga uaucgacggg      780

auacaggcga ucuacgggag gagucagaac ccggugcaac cgauagggcc gcagacgccg      840

aaggccugcg auucgaaauu gacguucgac gccaucacca ccaucagagg ggaggucaug      900

uuuuucaagg aucgcuuuua uaugaggacc aacccguuuu aucccgaggu cgaauugaac      960

uuuaucagcg ucuuuuggcc gcaguuaccg aacggcuugg aggccgccua ugaguucgcg     1020

gaucgcgacg aggugagauu cuuuaagggc aacaaauauu gggccgucca agggcaaaac     1080

gucuugcaug gguauccgaa agauauauau ucgaguuucg gguuuccgcg caccgucaaa     1140

cacauagacg ccgccuugag cgaagagaau accgggaaga cguauuuuuu cgucgccaau     1200

aaguauuggc gcuacgacga guacaagagg agcauggacc cgggguaccc gaagaugauc     1260

gcccacgauu ucccggggau cgggcauaag gucgacgccg ucuuuaugaa ggacggguuc     1320

uuuuacuuuu uccacgggac ccgccaguau aaguucgacc cgaagaccaa acgcauccuc     1380

accuugcaaa aggccaacuc gugguuuaau ugucgcaaga acugaggacu aguuauaaga     1440

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  5610
<211>  3283
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt10)

<400>  5610
gggagaaagc uuaccaugaa gcgcaagugc cugagcaagc ggcucaugcu ggccaucacc       60

auggccacca ucuucacggu gaacuccacc cugcccaucu acgcggccgu cgacaagaac      120

aacgccaccg ccgccgugca gaacgagagc aagcgcuaca ccguguccua ccucaagacg      180

cugaacuacu acgaccuggu cgaccuccug gugaagaccg agaucgagaa ccugccggac      240

cucuuccagu acagcuccga cgcgaaggag uucuacggca acaagacccg gaugagcuuc      300

aucauggacg agaucgggcg ccgggcgccc caguacaccg agaucgacca caagggcauc      360

cccacgcugg uggaggucgu gcgcgccggg uucuaccugg gcuuccacaa caaggagcuc      420

aacgagauca acaagcgguc cuucaaggag cgcgugaucc ccagcauccu ggccauccag      480

aagaacccga acuucaagcu ggggaccgag guccaggaca agaucguguc cgccaccggc      540

cuccuggccg gcaacgagac cgccccgccc gaggugguca acaacuucac gcccauccug      600

caggacugca ucaagaacau cgaccgguac gcccucgacg accucaagag caaggcccug      660

uucaacgugc ucgcggcccc gaccuacgac aucaccgagu accugcgcgc caccaaggag      720

aagcccgaga acacgcccug guacgggaag aucgacggcu ucaucaacga gcugaagaag      780

cucgcccugu acgggaagau caacgacaac aacuccugga ucaucgacaa cggcaucuac      840

cacaucgcgc cccuggggaa gcuccacagc aacaacaaga ucggcaucga gacccugacc      900

gaggugauga aggucuaccc guaccugucc augcagcacc uccagagcgc cgaccagauc      960

aagcggcacu acgacuccaa ggacgccgag ggcaacaaga ucccccugga caaguucaag     1020

aaggagggga aggagaagua cugccccaag accuacacgu ucgacgacgg caaggugauc     1080

aucaaggccg gggcccgcgu ggaggaggag aaggucaagc ggcuguacug ggccagcaag     1140

gaggugaacu cccaguucuu ccgcguguac ggcaucgaca agccccucga ggagggcaac     1200

ccggacgaca uccugaccau ggucaucuac aacagccccg aggaguacaa gcugaacucc     1260

gugcucuacg gguacgacac caacaacggc gggauguaca ucgagcccga gggcaccuuc     1320

uucacguacg agcgggaggc gcaggagagc accuacaccc uggaggagcu guuccgccac     1380

gaguacaccc acuaccucca ggggcgguac gccgugcccg gccagugggg ccgcacgaag     1440

cuguacgaca acgaccggcu gaccugguac gaggagggcg gggccgagcu guucgccggg     1500

agcacccgca ccuccggcau ccugccgcgc aagagcaucg ucuccaacau ccacaacacg     1560

acccggaaca accgcuacaa gcugagcgac accgugcacu ccaaguacgg ggccagcuuc     1620

gaguucuaca acuacgcgug cauguucaug gacuacaugu acaacaagga caugggcauc     1680

cucaacaagc ugaacgaccu ggccaagaac aacgacgucg acggcuacga caacuacauc     1740

cgggaccucu ccagcaacua cgcccugaac gacaaguacc aggaccacau gcaggagcgc     1800

aucgacaacu acgagaaccu gaccgugccc uucguggccg acgacuaccu gguccggcac     1860

gcguacaaga accccaacga gaucuacucc gagaucagcg agguggccaa gcucaaggac     1920

gccaaguccg aggugaagaa gucccaguac uucagcacgu ucacccugcg cgggagcuac     1980

accggcgggg ccuccaaggg caagcuggag gaccagaagg ccaugaacaa guucaucgac     2040

gacagccuca agaagcugga caccuacucc uggagcgggu acaagacccu gacggcguac     2100

uucaccaacu acaaggucga cuccagcaac cgggugaccu acgacguggu cuuccacggc     2160

uaccucccca acgagggcga cagcaagaac ucccugccgu acgggaagau caacggcacc     2220

uacaagggga cggagaagga gaagaucaag uucagcuccg agggcagcuu cgaccccgac     2280

ggcaagaucg uguccuacga gugggacuuc ggggacggca acaagagcaa cgaggagaac     2340

cccgagcacu ccuacgacaa gguggggacc uacaccguca agcugaaggu gaccgacgac     2400

aagggcgaga gcuccgugag cacgaccacc gccgagauca aggaccucuc cgagaacaag     2460

cugcccguca ucuacaugca cgugcccaag agcggggccc ugaaccagaa gguggucuuc     2520

uacggcaagg gcaccuacga ccccgacggg uccaucgccg gcuaccagug ggacuucggg     2580

gacggcagcg acuucuccag cgagcagaac cccucccacg uguacacgaa gaagggggag     2640

uacaccguga cccuccgcgu cauggacagc agcggccaga uguccgagaa gaccaugaag     2700

aucaagauca cggacccggu guaccccauc ggcaccgaga aggagcccaa caacagcaag     2760

gagaccgccu ccgggcccau cgugccgggc auccccguca gcgggaccau cgagaacacg     2820

uccgaccagg acuacuucua cuucgacgug aucacccccg gcgaggugaa gaucgacauc     2880

aacaagcugg gguacggcgg cgcgaccugg gucguguacg acgagaacaa caacgccgug     2940

agcuacgcca ccgacgacgg gcagaaccug uccggcaagu ucaaggccga caagcccggg     3000

cgguacuaca uccaccucua cauguucaac ggcagcuaca ugccguaccg caucaacauc     3060

gagggguccg ucggccggug aggacuaguu auaagacuga cuagcccgau gggccuccca     3120

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3240

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3283


<210>  5611
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt10)

<400>  5611
gggagaaagc uuaccaugug ggucacgaag uuguuaccgg cguuauuauu acaacacgug       60

uuguuacacu uguuguuauu gccgauagcg auaccguaug ccgaagggca gcgcaagcgc      120

cgcaauacca uccacgaguu uaagaagagu gccaaaacca cguugauaaa gaucgacccg      180

gccuuaaaaa ucaagacgaa aaaggucaac accgccgauc agugcgccaa ccgcugcacc      240

cgcaacaagg gguugccguu uaccuguaaa gccuucgucu ucgacaaggc ccgcaagcaa      300

uguuuguggu uuccguuuaa cucgaugagc ucggggguca agaaggaguu cgggcacgag      360

uucgauuugu augagaauaa ggauuauauc cgcaauugua uaaucgggaa agggaggucg      420

uauaaaggga ccgucagcau aaccaaaucg gggauaaaau gccaaccgug gucgaguaug      480

aucccgcaug agcauucguu ccucccgagc ucguacagag ggaaggauuu gcaagagaau      540

uauugcagga acccgagggg cgaggagggc gggccguggu gcuuuaccuc gaacccggaa      600

gucagguaug aggugugcga uaucccgcaa ugcagcgagg ucgaguguau gacguguaac      660

ggcgaaucgu acaggggguu gauggaccac accgagagcg ggaaaaucug ccaaaggugg      720

gaccaccaaa ccccgcauag acauaaauuu cucccggagc gcuauccgga uaaaggguuc      780

gacgacaacu acuguaggaa cccggacggg caaccccgcc cgugguguua uaccuuggau      840

ccgcauacga ggugggaaua uugcgccauc aaaaccugug ccgauaacac caugaacgau      900

accgacgucc cgcucgagac caccgagugu auacaggggc agggggaggg guaucgcggg      960

accgugaaca cgaucuggaa cgggaucccg ugccaaaggu gggacagcca auauccgcau     1020

gaacacgaua ugaccccgga gaacuuuaaa uguaaagauu ugagggagaa cuauuguagg     1080

aacccggacg gcagcgagag cccguggugc uucacgaccg acccgaauau aagggucggg     1140

uauuguaguc agaucccgaa uugcgacaug agccacgggc aagacugcua uaggggcaac     1200

gggaaaaacu acauggggaa ucucagucag acccgcagcg gguugaccug cagcaugugg     1260

gauaaaaaua uggaggaucu ccacaggcac auauuuuggg agccggacgc cucgaaauua     1320

aacgaaaacu auuguaggaa cccggacgac gacgcccacg ggccguggug uuauaccggg     1380

aacccguuga ucccguggga cuauuguccg aucaguaggu gcgaggggga cacgaccccg     1440

accaucguga accucgauca cccggucauc agcugcgcga agaccaagca gcucaggguc     1500

gucaacggca ucccgaccag gaccaauauc ggguggaugg ucucgcuccg cuaucgcaac     1560

aagcacauau guggggggag ccucaucaaa gaaucguggg ucuugaccgc caggcaaugc     1620

uuuccgagca gggaucucaa ggacuacgag gccugguugg ggauccacga cgugcauggg     1680

cgcggggacg aaaaguguaa gcaagucuug aacgucaguc aauuagucua cgggccggag     1740

gggagcgacu uaguccucau gaaauuggcg cgcccggccg uguuagacga cuucgucucg     1800

accaucgacc ucccgaauua cggguguacc aucccggaga aaacgucgug uucggucuau     1860

gggugggggu auaccgggcu cauaaauuac gacggguugc ucagggucgc ccacuuguau     1920

aucaugggga acgaaaagug uucgcaacac cacaggggca aagucaccuu aaacgaaagc     1980

gagaucugcg ccggcgccga gaaaaucggg agcgggccgu gcgaaggcga cuaugggggg     2040

ccguuggucu gcgaacagca caaaaugcgc auggucuugg gggugaucgu cccggggagg     2100

gggugcgcga ucccgaacag gccggggauc uucgugaggg ucgccuacua cgccaagugg     2160

auccauaaga ucauccucac cuauaaaguc ccgcaaagcu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5612
<211>  793
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt10)

<400>  5612
gggagaaagc uuaccauggg uacguggaua cucuucgcgu gcuuguuagg ugcggcguuc       60

gcgaugccgu uaccgccgca cccaggccac ccgggauaca ucaacuucuc guacgagguc      120

uuaacgccgc ucaaguggua ccagaguauc cgaccuccuu accccucgua cggauacgag      180

ccgauggggg guugguuaca ccaccagaua auaccaguau ugagucagca acacccgcca      240

acgcacacuu uacagccgca ccaccacauc cccguagucc ccgcgcagca accggucauc      300

ccgcaacagc cgaugaugcc gguacccggg cagcacucga ugacaccuau ccagcaccac      360

caaccgaacu ugccgccgcc ggcgcagcaa cccuaccagc cacagccggu ccagccucaa      420

ccccaccagc cuaugcagcc ucagccgccg guacacccga ugcagccguu accaccgcag      480

cccccguuac cgcccauguu cccgaugcaa ccccucccgc cgauguuacc ggacuuaacg      540

uuagaggcgu ggccuucgac ggacaagacg aagcgcgagg agguugacug aggacuaguu      600

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      660

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      780

agccaccaga auu                                                         793


<210>  5613
<211>  352
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt10)

<400>  5613
gggagaaagc uuaccaugcc guugccgccg cauccggguc acccggggua uauaaacuuc       60

ucguaugagg ucuugacgcc gcucaagugg uaccaaucga uucgcccgcc uuacccgagu      120

uauggguacg agccgauggg ggggugguga ggacuaguua uaagacugac uagcccgaug      180

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      300

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              352


<210>  5614
<211>  796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt10)

<400>  5614
gggagaaagc uuaccauggg uacauggaua uuauucgcgu gcuuggucgg ugcugcauuc       60

gcaaugccau uaccucccca cccaggccac ccgggguaca uuaauuucuc guacgaggua      120

uuaacgccgc uuaaauggua ccagaguaug aucaggccgc cguacucguc guacggauac      180

gaacccaugg gggguugguu acaucaccag auaauaccgg uagucucgca gcagcacccg      240

uuaacgcaca cguugcaauc gcaccaccac auaccgguag uaccggcgca gcaaccucgc      300

guuaggcagc aggcguuaau gccgguaccg gggcagcagu cgaugacacc gacccagcac      360

caccagccga acuuaccauu acccgcucaa cagccauucc agccgcaacc cguccagccg      420

caaccccauc agccgaugca accgcaaccg ccgguacagc cgaugcagcc guuguuaccg      480

cagccgccgu ugccacccau guucccguua cgcccuuuac cuccgaucuu accggacuua      540

cacuuagagg cauggccggc gacggacaag acgaagcagg aggagguaga cugaggacua      600

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      660

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      780

cagagccacc agaauu                                                      796


<210>  5615
<211>  355
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt10)

<400>  5615
gggagaaagc uuaccaugcc guugccgccg cacccgggcc auccggggua cauaaauuuu       60

ucguacgaag ucuugacgcc gcucaaaugg uaucaaucga ugauccgccc gccguauagc      120

aguuacgggu augaaccgau gggggggugg ugaggacuag uuauaagacu gacuagcccg      180

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      300

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           355


<210>  5616
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt10)

<400>  5616
gggagaaagc uuaccaugcc cggagucgcg cgauugccau ugcucuuagg uuuguuauua       60

uuaccacgcc cggggaggcc ccucgacuua gcggacuaca cguacgacuu ggcagaggag      120

gacgacucug aaccuuuaaa cuacaaggac ccgugcaagg cugccgcguu cuuaggggac      180

auagcguugg acgaggagga cuuacgcgcu uuccaagucc agcaggcggu ugacuuaagg      240

cgccacacgg cgcggaaaag uucgaucaag gcggcgguac ccgggaacac aaguacgccg      300

ucgugccaaa guacaaacgg acaaccacag cgcggggcgu gcggacggug gcgagggagg      360

ucgaggagua ggcgagcagc caccucgcgu cccgagcggg uauggccgga cgguguaauu      420

ccauucguaa uagguggcaa cuucacggga agucagcggg cgguauuccg ccaggcgaug      480

cgacacuggg agaaacacac augcguuacg uucuuggagc gaaccgacga ggacucguac      540

auaguauuua cguaccgucc augcggcugc ugcaguuacg uagggcgaag ggguggcggu      600

ccgcaagcga ucucgauagg uaagaacugc gacaaguucg guaucguagu ucacgaguua      660

ggucacguug uagguuucug gcacgagcac acgcgaccug accgcgacag gcacgucagu      720

auaguccgcg agaacauaca gccgggacag gaguacaacu ucuuaaaaau ggagccgcaa      780

gagguugagu cguuggguga gacguacgac uucgacucga uaaugcacua cgcgcgaaac      840

acguucucgc gcgggauuuu cuuagacaca auaguuccga aauacgaggu aaacggcguc      900

aagccgccga uaggccagcg gacucgcuug ucgaagggug acauagcgca ggcgcggaag      960

uuguauaagu gcccggcgug cggugagaca uuacaggacu cgacgggaaa cuuuaguucg     1020

cccgaguacc cuaacggcua cucggcgcac augcacugcg ucuggcgaau aucgguaacu     1080

ccgggggaga agauuauuuu aaauuucacu ucauuggauu uauauagguc gcgauuaugu     1140

ugguacgacu acguagaagu aagggacggg uuuuggcgua aggccccuuu gcgugggcga     1200

uucugcggau cgaaguuacc ggagccgaua guaaguacgg acucgcguuu auggguagag     1260

uuccgaaguu cgaguaacug gguagguaag gguuucuucg ccguuuacga ggcaauaugc     1320

gguggggacg uaaagaagga cuacggucau auacagucuc cgaauuaccc ggacgacuac     1380

aggccuagua agguauguau auggcgcauc caagucucgg agggauucca uguuggguug     1440

acguuucaga guuucgagau agagaggcac gacucgugcg cguacgauua cuuagaggua     1500

agggacggac auucggaguc gaguacuuua auaggacgau acugcgguua cgagaagccg     1560

gacgacauaa agucgacuuc gucgcgauug ugguuaaagu ucguuucgga cggaaguaua     1620

aacaaggcag guuucgcggu uaacuucuuu aaggagguag acgagugcuc gcgaccgaac     1680

cgaggcgguu gcgagcaacg augcuuaaac acguugggau cuuacaaaug cucuugcgac     1740

ccggguuacg aguuggcgcc ggauaagagg cgaugcgagg cggcaugcgg ggguuucuua     1800

acaaaguuga acgguucgau aacaucgccc ggguggccga aggaguaccc gccgaacaag     1860

aacugcauau ggcaauuagu cgcgccgaca caauaccgga uuucguuaca guucgacuuc     1920

uucgagacgg aggguaacga cgucuguaag uacgacuucg ucgagguccg aucggguuug     1980

acugcggacu caaaguuaca cgguaaguuc ugcggcucgg agaagccgga gguaauuaca     2040

ucgcaguaca acaacaugcg agucgaguuc aagucggaca acacgguaag uaagaagggg     2100

uucaaggcac acuucuucuc ggauaaggac gaguguucga aagacaacgg ggguugccaa     2160

caggacugcg uaaacaccuu cgguucguac gagugucagu gccgaucggg uuucguauua     2220

cacgacaaca agcacgacug caaggaggca ggaugcgacc auaaggucac gucgacuucg     2280

gggacgauaa cgucgccgaa cuggccggac aaguacccgu cgaagaagga gugcaccugg     2340

gcgaucucgu caacuccggg ucaucgaguu aaguugacgu ucauggagau ggauauugag     2400

ucgcagcccg agugcgcgua cgaccacuua gagguauucg acgggcguga cgcgaaagca     2460

ccgguauuag gaagguucug cgguucgaag aaacccgaac cgguuuuggc gacgggaagu     2520

cguauguucu uacgguucua cucggacaau aguguacaac guaagggguu ccaagcaucg     2580

caugcgacgg agugcggugg ucagguccga gcggacguua aaacgaaaga cuuauacucg     2640

cacgcgcagu ucggggacaa uaacuacccg ggcgggguug acugcgagug gguuauaguc     2700

gcagaggagg gguacggugu agaguuagua uuccagacuu ucgaggucga ggaggagacg     2760

gacugcgguu acgacuacau ggaguuauuc gacgguuacg acucgacggc gccacgauua     2820

gguagguacu gcgggucggg accgccggag gagguauacu cagccgguga caguguauua     2880

gucaaguuuc acucugacga cacgauaacg aagaagggcu uccacuuacg uuacacgagu     2940

acgaaguucc aggacacguu acacucucga aagugaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  5617
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt10)

<400>  5617
gggagaaagc uuaccauggu cgcgggcacg agguguuugu uggcacucuu auugccgcaa       60

guauuguuag ggggggccgc gggguugguc cccgaguuag ggaggcgcaa guucgccgcc      120

gcaagcagcg ggaggccgag cagucagccg agcgacgagg uauuaucgga guucgagcuc      180

agauuauugu cgauguucgg guuaaaacaa cgcccgacgc cgucgcgcga cgcggucguc      240

ccgccguaua uguuggacuu auauaggcgc cacagcgggc agcccgggag cccggcgccg      300

gaccacagac ucgagcgcgc ggcgucgagg gcgaacacgg ucaggucguu ccaccaugaa      360

gaaagccucg aagaauugcc ggaaacaucg ggcaaaacga cgagacgcuu cuucuuuaau      420

cucucgagca uaccgaccga ggaguuuaua acgagcgccg aguugcaagu cuucagggaa      480

cagaugcaag augcgcucgg gaacaauucg ucguuccauc acaggauaaa uauauaugaa      540

auaauuaaac cggccacggc gaacagcaaa uucccgguca cgcgcuugcu cgacacgcgc      600

cucgucaauc agaaugcguc gcgcugggaa ucguuugaug uaacgccggc ggucaugaga      660

uggaccgccc aggggcacgc gaaccauggg uucgucgucg aagucgcgca ccucgaggag      720

aaacaagggg uaaguaagcg ccauguccgc auuucgcgca gccuccacca agaugaacac      780

ucguggagcc agauucgccc gcucuugguc acguuugggc augaugggaa aggccauccg      840

uugcacaaac gcgaaaaaag gcaagcgaaa cacaaacaaa gaaaaagguu gaagaguucg      900

uguaagcgcc acccgcucua cgucgacuuc ucggacgucg guuggaauga cuggauaguc      960

gccccgccug gcuaucacgc guuuuauugc cacggggaau gcccguuucc guuagccgau     1020

cauuuaaaca guacgaauca ugcgauaguc cagacacucg uaaacagcgu caacagcaag     1080

auaccgaaag cgugcugugu acccacggaa uugucggcga uaagcauguu auauuuggac     1140

gagaaugaaa aggucguccu caaaaauuau caggacaugg ucgucgaggg guguggcugu     1200

aggugaggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  5618
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt10)

<400>  5618
gggagaaagc uuaccaugau accgggaaac aggauguuaa ugguaguauu guugugccag       60

guauuauugg guggugccuc gcacgcgagu uugaucccgg agaccgguaa gaagaaggua      120

gcggagaucc agggccacgc ggggggccga cguagcgguc agucgcacga guuauugcga      180

gacuucgagg ccacgcucuu acagauguuc ggucuucgcc gaaggccgca gccgucuaag      240

ucggccguca uacccgacua caugcgagac uuauaccgau uacagucggg cgaggaggag      300

gaggagcaga uccacaguac gggguuagag uacccggagc guccggccuc gcgagcgaac      360

acgguccgcu cguuccacca cgaggagcac uuggagaaca uaccgggcac cucggagaac      420

agugcguuca gauucuuauu caacuuaucg aguaucccag agaacgaggu gauaucuagu      480

gcggaguugc gcuuauuccg ugagcagguu gaccaagggc cggacuggga gcgcggcuuc      540

caccgaauca acaucuacga ggugaugaag ccgccggcgg agguaguacc cggucacuua      600

aucacucguc ucuuagacac gcgauuagua caccacaacg uaacgaggug ggagacguuc      660

gacgucaguc cggcgguauu gagguggacg cgcgagaagc agcccaacua cggauuagcg      720

aucgagguca cgcaccuaca ccagacccgu acgcaccagg gccagcacgu ccgaauaucg      780

cgaucgcuac cgcagggauc ggguaacugg gcgcaauuaa gaccguuguu aguaacguuc      840

ggccacgacg ggcgaggcca cgcuuuaacg cgucgacgac gugcgaagcg cucgccgaag      900

caccacucgc agcgagcgcg aaagaagaac aagaacugcc gacgucacag ucuuuacguu      960

gacuucucgg acgucggaug gaacgacugg auaguugcgc cgccgggcua ccaggcguuc     1020

uacugccacg gggacugccc guucccguua gccgaccacu uaaacaguac caaccacgcc     1080

aucguccaga cgcuuguaaa cucgguaaac aguucaauac ccaaggcgug cugcguaccc     1140

acggaguuaa gugcgaucuc gauguuauac uuggacgagu acgacaaggu uguuuuaaag     1200

aacuaccagg agaugguugu ggagggcugc ggaugccguu gaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  5619
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt10)

<400>  5619
gggagaaagc uuaccaugcc cggcuuaggc agacgcgccc aaugguuaug uugguggugg       60

ggcuuauuau guucguguug uggcccgccc cccuuaagac ccccgcuccc ggccgcggcc      120

gcggcggcgg cgggcggcca auuauuaggc gaugggggcu cgccggggag gaccgaacaa      180

ccccccccca gcccccaaag uaguagcggg uuuuuauaua gaagauugaa aacccaagaa      240

aaaagagaaa ugcaaaaaga aauacucagc gucuuaggcu ugccccauag accgagaccg      300

uuacaugggu ugcagcaacc ccaaccgccc gccuugagac aacaagaaga acaacaacaa      360

caacaacaau uaccgagggg ggaaccgccg ccgggcaggu uaaaaagugc cccguuguuu      420

auguuagacu uauauaaugc guuaagugcg gauaaugaug aagauggcgc cagcgaaggc      480

gaacgccaac aaaguuggcc gcaugaggcc gcgucgagca gucaaaggag acaacccccg      540

cccggggcgg cccaucccuu gaauaggaaa ucguuguuag cgccggggag cgggucgggg      600

ggggccaguc cguuaacguc ggcccaagau ucggcguuuu ugaaugaugc cgauauggug      660

augucguucg ucaauuuagu cgaauaugau aaagaauuua guccgaggca aaggcaucau      720

aaggaauuua aauuuaaucu cagucaaauc ccggaagggg aagucgucac cgccgccgag      780

uuuaggauau auaaagauug cgucaugggc ucguucaaga aucagaccuu cuugauaucg      840

aucuaccagg ugcuccaaga acaccaacau cgcgauagcg auuuauuccu ccucgauacg      900

agggucgucu gggcgagcga ggaggggugg uuagaguucg auauaaccgc gaccucgaac      960

uuaugggucg ucaccccgca acacaauaug ggcuugcaau uaucggucgu cacccgcgac     1020

ggggugcaug ugcauccgag ggcggccggg uuagucgggc gcgaugggcc guaugauaaa     1080

caaccguuua uggucgccuu uuuuaagguc ucggaagucc augucaggac gacgcgcagc     1140

gcgaguucga gaaggaggca gcaaucgagg aacaggagca cgcaaaguca agaugucgcc     1200

agagugaguu cggccagcga cuauaauucg ucggagcuca agaccgcgug ucgcaaacac     1260

gaauuauacg ucucguuuca ggauuuaggg uggcaagauu ggauaaucgc cccgaaaggg     1320

uacgccgcga acuauugcga cggggagugu aguuuuccgu ugaaugccca uaugaacgcc     1380

acgaaucaug ccaucgucca aacgcucguc cauuugauga auccggaaua cgugccgaag     1440

cccuguugcg ccccgaccaa auugaacgcg auaagcgucu uguauuucga cgauaauagu     1500

aacgugaucu uaaagaagua ucgcaacaug gucguccgcg ccugcgggug ucauugagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  5620
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt10)

<400>  5620
gggagaaagc uuaccaugca cguaagaucg uuacgagcgg cggcuccgca caguuucgua       60

gcguuguggg ccccguuauu cuuauugcga ucggcguuag cggacuucag uuuagacaac      120

gagguacacu cgaguuucau acaccgaaga uugcgcucgc aggagaggcg cgagaugcag      180

cgagagauau uaaguauauu aggguugccg caccgaccca ggccccacuu gcaggggaag      240

cacaacucgg cuccaauguu cauguuagac uuauacaacg cgauggcggu agaggagggg      300

gggggucccg ggggucaggg cuucaguuac cccuacaagg cgguauucuc uacgcagggu      360

ccgccguuag cgaguuuaca ggacucgcac uucuugacgg acgcggacau gguaaugagu      420

uucguaaacu uaguagagca cgacaaggag uucuuccacc cgcgauacca ccacagggag      480

uuccgauucg acuuaucgaa gauacccgag ggggaggcgg uaacggcggc ggaguucagg      540

auauacaagg acuacauccg agagagauuc gacaacgaga cguuccgaau aaguguauac      600

cagguauugc aggagcacuu agguagggag ucggacuuau ucuuguuaga cagucgcacg      660

uuaugggcgu cggaggaggg uugguugguc uucgacauaa cggcgacgag uaaccacugg      720

gucguaaacc ccaggcacaa cuuagguuua caguugucgg uagagacauu agacggucag      780

ucgauaaacc cgaaguuagc cggguugauc ggucgacacg gcccgcagaa caagcagccg      840

uucaugguag ccuucuucaa ggcgacggag guacacuuca ggaguauaag gucgacgggu      900

aguaagcagc gaucgcagaa caggaguaag acaccaaaga accaggaggc guuaagaaug      960

gcgaacguag cugagaacuc gaguucggac cagaggcagg cgugcaagaa gcacgaguua     1020

uacguaaguu uccgcgacuu gggguggcag gacuggauaa uagcgccgga gggguacgca     1080

gcguacuacu gcgaggguga gugcgcguuc cccuuaaacu cguacaugaa cgcgacgaac     1140

cacgcgauag uacagacguu aguacacuuc aucaacccgg agacaguacc gaagccgugc     1200

ugcgcgccga cgcaguugaa cgcgauaagu guauuauacu ucgacgacuc gaguaacgua     1260

aucuuaaaga aguacaggaa caugguagua cgagcgugcg guugccacug aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  5621
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt10)

<400>  5621
gggagaaagc uuaccaugaa ggcgucggcc gcguuacuau gcuuauuacu uaccgccgcg       60

gcguucucgc cgcagggcuu agcgcaaccg guagguauaa acaccaguac gacaugcugc      120

uacagguuca uaaacaagaa gaucccgaag cagcgauuag agaguuaccg ucguacgacg      180

agcucucacu gcccgcguga ggcggucaua uucaaaacga aguuagacaa ggagauaugc      240

gcagacccca cccagaagug gguacaggac uucaugaagc acuuagacaa gaagacgcag      300

acgccuaagu ugugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  5622
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt10)

<400>  5622
gggagaaagc uuaccauguu auugaccuug auaaucuuac ucccggucgu cagcaaguuc       60

ucguucgucu cguugagcgc cccccaacau uggucgugcc cggaggggac cuuggccggg      120

aacggcaaca guaccugcgu cgggccggcc ccguuucuca ucuuuaguca cgggaacucg      180

auauuccgca ucgauaccga ggggacgaac uacgaacagc ucgucgucga cgccggggug      240

agcgucauaa uggacuucca cuacaacgaa aagcgcauau acugggucga ccucgagcgc      300

caguugcucc agcgcgucuu cuuaaacggc agccgccagg aacgcgucug caacaucgaa      360

aagaacguca gcgggauggc caucaacugg aucaacgagg aggucaucug gagcaaccag      420

caagagggga uaaucaccgu caccgacaug aaggggaaca acagucauau cuugcucucg      480

gcccucaagu acccggccaa cgucgccguc gacccggucg agcgcuucau cuucuggagc      540

agcgaagucg ccgggucguu guaccgcgcc gacuuggacg gggucggggu caaagccuua      600

cucgaaacca gcgaaaagau caccgccguc agccucgacg ucuuggacaa aagauuauuc      660

uggauccaau auaaucgcga ggggucgaac agcuugaucu guaguugcga cuacgacggg      720

gggagcgugc auaucucgaa gcacccgacc caacacaacc ucuucgccau gaguuuguuc      780

ggggauagga uauuuuacag caccuggaag augaaaacca ucuggaucgc gaauaagcau      840

accgggaaag auaugguccg caucaauuug cacagcagcu ucgucccguu gggggaguua      900

aaggucgucc acccguuggc ccagccgaaa gccgaggacg auaccuggga accggaacaa      960

aaguugugua agcuccgcaa ggggaauugu ucgucgaccg ucugcggcca ggauuugcaa     1020

agccaucucu guaugugcgc cgaaggguau gcguugucga gggauagaaa auauugcgag     1080

gacgucaacg agugcgccuu cuggaaccac gggugcaccu ugggcugcaa gaauacgccg     1140

gggaguuacu auuguaccug uccggucggg uucgucuuau ugccggacgg caagaggugc     1200

caccaguugg ucaguugccc gaggaacguc agcgaguguu cgcacgauug cgucuuaacc     1260

agcgaggggc cgcucugcuu uugcccggag gggagcgucu uggaacgcga cggcaagacc     1320

ugcucggggu gcaguagccc ggacaacggg gggugcucgc aauugugugu cccguugucg     1380

ccggucaguu gggagugcga cuguuucccg ggcuacgauu ugcaguuaga cgagaagucg     1440

ugcgccgcca gcgggccgca gccguuccuc uuauucgcga acagccagga caucaggcau     1500

augcacuucg acgggaccga uuacgggacc uuauugucgc aacaaauggg gauggucuac     1560

gcguuggacc acgauccggu cgagaacaaa aucuauuucg cgcacaccgc guuaaaaugg     1620

aucgaacgcg ccaacaugga cgggagucaa agggagcgcu ugaucgaaga gggggucgac     1680

gucccggagg gguuggccgu cgauuggauc gggaggcgcu uuuacuggac cgaucgcggc     1740

aagagcuuaa ucgggcgcuc ggaccucaac ggcaagagga guaagaucau aaccaaagaa     1800

aauauaagcc agccgagggg gaucgccguc cacccgaugg cgaaacgccu cuuuuggacc     1860

gacaccggca ucaacccgag gaucgagucg agcaguuugc agggguuggg gagguuaguc     1920

aucgcgucga gcgacuugau auggccgucg gggaucacca ucgauuuucu caccgauaaa     1980

cucuauuggu gugacgcgaa acaaagcguc aucgagaugg cgaacuuaga cgggagcaag     2040

aggaggcgcu ugacgcaaaa cgacgucggg cauccguucg ccgucgccgu cuucgaagac     2100

uacgucuggu uuagcgacug ggccaugccg agcgucaugc gcgucaauaa acgcaccggg     2160

aaggaccgcg ucagguugca ggggucgaug uuaaaaccga gcagcuuagu cgucguccac     2220

ccgcucgcca agccgggggc cgacccgugu cucuaccaga auggggggug cgagcacauc     2280

uguaagaaac gcuuggggac cgccuggugc agcugcaggg agggguucau gaaggcgagc     2340

gacggcaaga ccugcuuagc cuuagacggg caccaauuac ucgccggggg ggaggucgac     2400

uugaaaaauc aggucacccc gcucgauaua cucaguaaaa cccgcgucag cgaggacaau     2460

aucaccgaga gccagcauau guuggucgcc gagauaaugg ucagcgacca ggacgauugc     2520

gccccggucg gguguucgau guacgccaga ugcaucagcg aaggggaaga cgcgaccugc     2580

caaugccuca agggguucgc cggcgacggg aaguugugca gcgacaucga cgagugcgaa     2640

augggggugc cggucugucc gccggcgagu aguaaaugua uaaauacgga ggggggguac     2700

guguguagau guagcgaggg guaucagggg gacggcaucc auugcuugga caucgacgaa     2760

ugucaguuag gcgaacauuc gugcggggaa aacgcgucgu guaccaacac cgaagggggg     2820

uacacgugua ugugcgccgg gagguuaagc gagccggggu uaaucugucc ggauagcacc     2880

ccgccgccgc auuugcgcga ggacgaucau cauuacagug uccgcaacuc ggauagcgag     2940

ugcccguuaa gucaugacgg cuauuguuug cacgacgggg ucuguaugua caucgaggcc     3000

cucgauaaau acgccuguaa uugcgucguc ggguauauag gcgaaaggug ccaauauagg     3060

gauuuaaaau ggugggaguu aaggcaugcc gggcauggcc aacaacaaaa agugauaguc     3120

gucgccgugu gugucgucgu cuuggugaug uuauuguugu uaucguuaug gggcgcgcau     3180

uauuaucgca cccaaaaauu auugagcaag aauccgaaaa acccguacga agaaagcucg     3240

cgcgacgucc gcucgaggcg cccggccgau accgaagacg gcaugaguag cuguccgcag     3300

ccgugguucg ucgucaucaa ggagcaucag gauuugaaaa acggcgggca gccggucgcc     3360

ggggaagacg ggcaagccgc cgacggcagc augcagccga ccagcuggcg ccaagaaccg     3420

caacucugcg ggauggggac cgaacagggg uguuggaucc cggucaguuc ggacaaaggg     3480

aguugcccgc aagucaugga aaggucguuc cacaugccga guuacggcac ccaaacguug     3540

gagggcgggg uggaaaaacc gcacagcuug uugagcgcca auccgcucug gcagcagcgc     3600

gcguuagauc cgccgcauca gauggaauua acccaaugag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  5623
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt10)

<400>  5623
gggagaaagc uuaccaugac ggccggccgc cgcauggaaa uguugugcgc ggggcgcgug       60

ccggccuuau uauuguguuu aggguuucac uuguugcaag ccguguuguc gaccaccguc      120

aucccgagcu gcauaccggg ggaaaguucg gacaauugua ccgcccucgu ccaaaccgag      180

gauaacccga gggucgccca ggucagcauc accaaaugcu cgagcgauau gaacggguac      240

ugccuccacg ggcaauguau auacuuaguc gauaugucgc agaauuauug ucgcugcgag      300

gucggguaca ccggggugag gugcgagcau uuuuuccuca cggugcauca gccgcucucg      360

aaggaguacg ucgcccucac ggucaucuug aucauccucu ucuugauaac cguggugggg      420

aguaccuacu acuuuugucg cugguaucgc aacaggaagu cgaaggagcc gaaaaaagag      480

uacgaacgcg ucacgagcgg cgacccggaa cucccccagg ugugaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  5624
<211>  685
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt10)

<400>  5624
gggagaaagc uuaccauggc ggagggugag auaacgacgu ucacugcguu aacggagaag       60

uucaacuuac cgccggguaa cuacaagaag cccaaguugu uauacugcuc gaacgggggg      120

cacuucuuac gaauauuacc agacggcacg guagacggua cccgagaccg gucggaccag      180

cacauccagu uacaauuauc ggcggagagu guuggcgagg uauacaucaa gucgacugag      240

acagggcagu acuuggcgau ggacacggac ggguuauugu acgggaguca aacgccgaac      300

gaggagugcu uauucuuaga gcgcuuggag gagaaccacu acaacacgua caucucgaag      360

aagcacgcgg agaagaacug guucguaggg uuaaagaaga acgguaguug caagcggggg      420

ccacgcacgc acuacgguca gaaggcgauc uuauucuugc cguuaccagu aucgagugac      480

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      540

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      660

ggcucuuuuc agagccacca gaauu                                            685


<210>  5625
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt10)

<400>  5625
gggagaaagc uuaccauggu gggcgucggg ggcggggacg uggaggacgu gaccccgcgc       60

ccgggcgggu gccagaucuc gggccggggc gcccgcgggu gcaacggcau ccccggggcc      120

gcggccuggg aggccgcccu gccccggcgc cggccccgcc ggcacccguc cgucaacccc      180

cgcucgcggg ccgcgggcuc gccccgcacc cgggggcgcc ggacggagga gcgccccucc      240

ggcucccggc ucggcgaccg cgggcggggc cgcgcccugc ccgggggccg gcugggcggg      300

cgcggccggg ggcgcgcccc cgagcgcgug ggcgggcggg gccgcggccg ggggaccgcc      360

gcgccccgcg ccgcccccgc cgcccggggc ucgcgcccgg ggcccgcggg caccauggcc      420

gccgggucca ucaccacgcu ccccgcccug cccgaggacg gcggcucggg ggccuucccg      480

cccggccacu ucaaggaccc caagcggcug uacugcaaga acgggggcuu cuuccuccgc      540

auccaccccg acgggcgggu ggacggcguc cgcgagaagu ccgacccgca caucaagcug      600

cagcugcagg cggaggagcg gggcguggug ucgaucaagg gggucugcgc caaccgcuac      660

cucgccauga aggaggacgg ccggcugcug gccuccaagu gcgugaccga cgagugcuuc      720

uucuucgagc gccucgaguc gaacaacuac aacaccuacc ggucccgcaa guacaccucg      780

ugguacgugg ccuuaaagcg gacggggcag uacaaguuag gcuccaagac cggccccggg      840

cagaaggcga uccucuucuu acccaugucg gccaaguccu gaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  5626
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt10)

<400>  5626
gggagaaagc uuaccaugca caaguggaua uuaacgugga uauugccgac guuauuauac       60

aggucgugcu uccacauaau augcuugguc gggacaauaa guuuagcgug caacgacaug      120

acgcccgagc aaauggcgac gaacguaaau ugcucgaguc cggagagaca cacgaggucg      180

uaugacuaua uggagggggg cgacauaaga gucaggagau uauucugcag gacacaaugg      240

uauuugagaa uagacaagag gggcaaaguc aaggggacgc aagagaugaa aaacaacuau      300

aacauaaugg agauaagaac gguagccguc ggcauagucg cgauaaaagg gguagagagu      360

gaguucuauu uagcgaugaa caaggagggg aaguuauaug cgaagaagga gugcaacgag      420

gacugcaauu ucaaggaguu gauauuagag aaccacuaua acacguacgc gucggccaag      480

uggacacaca acggcgggga gauguucguc gcguuaaacc aaaagggcau accggucagg      540

gggaagaaga cgaagaaaga gcaaaagacg gcgcacuucu ugccgauggc gauaacguga      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  5627
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt10)

<400>  5627
gggagaaagc uuaccaugaa guuguuaccc ucaguuguac ucaaauuauu cuuagcggcc       60

guauuaagug cucuugugac cggcgagucg uuggagcguu ugcgccgcgg ucuugcagcg      120

ggcacgagua acccggaccc gccgacgguc ucgaccgacc aguuacuccc ucucgggggc      180

gggcgcgacc guaagguucg ggaccuccag gaggcggacu uagaccuccu acguguuacg      240

cuuucgucga agccccaggc cuuggcgacc ccuaacaagg aggagcacgg uaagcguaag      300

aagaagggga aggggcuugg caagaagcgu gacccgugcu ugcgaaagua caaggacuuc      360

ugcauacacg gggagugcaa guacgucaag gaguuacgag cgccgaguug caucugccac      420

ccgggcuacc acggggagcg augccacggc uugucguuac cgguagagaa ccguuuguac      480

acuuacgacc acacuaccau acucgccgua gucgcgguug ucuuaucguc gguaugcuua      540

uuaguaauag uaggcuuauu aauguuccga uaccaccgac gcgggggcua cgacguagag      600

aacgaggaga aggugaagcu agggaugacg aacucgcacu gaggacuagu uauaagacug      660

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  5628
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt10)

<400>  5628
gggagaaagc uuaccaugug ggucacgaag uuguuaccgg cguuauuauu acaacacgug       60

uuguuacacu uguuguuauu gccgauagcg auaccguaug ccgaagggca gcgcaagcgc      120

cgcaauacca uccacgaguu uaagaagagu gccaaaacca cguugauaaa gaucgacccg      180

gccuuaaaaa ucaagacgaa aaaggucaac accgccgauc agugcgccaa ccgcugcacc      240

cgcaacaagg gguugccguu uaccuguaaa gccuucgucu ucgacaaggc ccgcaagcaa      300

uguuuguggu uuccguuuaa cucgaugagc ucggggguca agaaggaguu cgggcacgag      360

uucgauuugu augagaauaa ggauuauauc cgcaauugua uaaucgggaa agggaggucg      420

uauaaaggga ccgucagcau aaccaaaucg gggauaaaau gccaaccgug gucgaguaug      480

aucccgcaug agcauucguu ccucccgagc ucguacagag ggaaggauuu gcaagagaau      540

uauugcagga acccgagggg cgaggagggc gggccguggu gcuuuaccuc gaacccggaa      600

gucagguaug aggugugcga uaucccgcaa ugcagcgagg ucgaguguau gacguguaac      660

ggcgaaucgu acaggggguu gauggaccac accgagagcg ggaaaaucug ccaaaggugg      720

gaccaccaaa ccccgcauag acauaaauuu cucccggagc gcuauccgga uaaaggguuc      780

gacgacaacu acuguaggaa cccggacggg caaccccgcc cgugguguua uaccuuggau      840

ccgcauacga ggugggaaua uugcgccauc aaaaccugug ccgauaacac caugaacgau      900

accgacgucc cgcucgagac caccgagugu auacaggggc agggggaggg guaucgcggg      960

accgugaaca cgaucuggaa cgggaucccg ugccaaaggu gggacagcca auauccgcau     1020

gaacacgaua ugaccccgga gaacuuuaaa uguaaagauu ugagggagaa cuauuguagg     1080

aacccggacg gcagcgagag cccguggugc uucacgaccg acccgaauau aagggucggg     1140

uauuguaguc agaucccgaa uugcgacaug agccacgggc aagacugcua uaggggcaac     1200

gggaaaaacu acauggggaa ucucagucag acccgcagcg gguugaccug cagcaugugg     1260

gauaaaaaua uggaggaucu ccacaggcac auauuuuggg agccggacgc cucgaaauua     1320

aacgaaaacu auuguaggaa cccggacgac gacgcccacg ggccguggug uuauaccggg     1380

aacccguuga ucccguggga cuauuguccg aucaguaggu gcgaggggga cacgaccccg     1440

accaucguga accucgauca cccggucauc agcugcgcga agaccaagca gcucaggguc     1500

gucaacggca ucccgaccag gaccaauauc ggguggaugg ucucgcuccg cuaucgcaac     1560

aagcacauau guggggggag ccucaucaaa gaaucguggg ucuugaccgc caggcaaugc     1620

uuuccgagca gggaucucaa ggacuacgag gccugguugg ggauccacga cgugcauggg     1680

cgcggggacg aaaaguguaa gcaagucuug aacgucaguc aauuagucua cgggccggag     1740

gggagcgacu uaguccucau gaaauuggcg cgcccggccg uguuagacga cuucgucucg     1800

accaucgacc ucccgaauua cggguguacc aucccggaga aaacgucgug uucggucuau     1860

gggugggggu auaccgggcu cauaaauuac gacggguugc ucagggucgc ccacuuguau     1920

aucaugggga acgaaaagug uucgcaacac cacaggggca aagucaccuu aaacgaaagc     1980

gagaucugcg ccggcgccga gaaaaucggg agcgggccgu gcgaaggcga cuaugggggg     2040

ccguuggucu gcgaacagca caaaaugcgc auggucuugg gggugaucgu cccggggagg     2100

gggugcgcga ucccgaacag gccggggauc uucgugaggg ucgccuacua cgccaagugg     2160

auccauaaga ucauccucac cuauaaaguc ccgcaaagcu gaggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  5629
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt10)

<400>  5629
gggagaaagc uuaccauggc gaaggcggcg gcaauaggga uagacuuagg uacgacguac       60

ucgugcguug guguauucca gcacgguaag guagagauaa uagcgaacga ccaggguaac      120

cggacgacgc cgaguuacgu cgcguucacc gacacggagc gcuugaucgg ggacgccgcg      180

aagaaccagg uagcuuuaaa cccacaaaac acgguuuucg acgcaaagcg acucauaggg      240

cgaaaguucg gggaccccgu cguacaauca gacaugaagc acuggccguu ccaggucaua      300

aacgacggug acaagccgaa gguccaggua aguuacaagg gcgagacgaa ggcguucuac      360

ccugaggaga ucucaaguau gguauugacg aagaugaagg agauagcgga ggcauacuua      420

ggauaccccg ugacgaacgc cguaaucacg guccccgcgu acuucaacga cucucagcgg      480

caggcgacga aggacgcagg cguaaucgca ggguuaaacg uauugcgcau cauaaacgag      540

ccgaccgcgg cggcgauagc auacggguua gaccggaccg ggaaggguga gcgaaacgua      600

uuaaucuucg acuugggugg ggguacguuc gacgucucga uauuaaccau cgacgacggc      660

auauucgagg uaaaggcgac cgccggggac acgcacuuag gcggggagga cuucgacaac      720

cgauugguca accacuucgu agaggaguuc aagcgaaagc acaagaagga cauaucgcag      780

aacaagcgug cgguaagaag guuacgaacg gcgugcgagc gggcuaagcg cacguuaagu      840

ucgaguacgc aggcgucguu ggagauagac aguuuauucg aggguauaga cuucuacacu      900

ucgauaacgc gugcacgauu cgaggaguua ugcucggacu uauucagguc gacguuagag      960

ccgguagaga aggcauuacg agacgcgaag uuggacaagg cacagauaca cgacuuagua     1020

uuaguaggug guucgacgcg gauaccgaag guacagaagu uguuacagga cuucuucaac     1080

ggucgagacu uaaacaaguc gaucaacccg gacgaggcgg uagcguacgg ggccgcggua     1140

caggccgcga uauugauggg ugacaagagu gagaacguac aggacuuauu auuauuagac     1200

guagcacccu uaucuuuggg uuuagagacc gcgggugggg ucaugacggc guuaauaaag     1260

cgaaacucga cgaucccgac gaagcagacc cagaucuuca cuacguacuc ggacaaccag     1320

ccggguguau ugauccaggu auacgagggu gagcgagcga ugaccaagga caacaacuua     1380

uuaggacguu ucgaguuguc ggguauaccg cccgcaccuc gagggguccc gcagaucgag     1440

gucacguucg acaucgacgc gaacgguauc uuaaacguaa cggcgaccga caaaaguacg     1500

gggaaggcca acaagaucac gauaacgaac gacaaggguc gauuaucgaa ggaggagaua     1560

gagaggaugg uccaggaggc agagaaguac aaggccgagg acgaggucca gagagagcga     1620

guaagugcga agaacgcguu ggagucguac gcguucaaca ugaagagugc ggucgaggac     1680

gaggguuuaa aggguaagau cucggaggcc gacaagaaga aggucuuaga caagugccag     1740

gagguuauau cuugguuaga cgcgaacacg uuagcggaga aggacgaguu cgagcacaag     1800

cgcaaggagu uagagcaggu augcaacccg auaauaucgg guuuguacca gggggcgggc     1860

gggccggguc cgggugguuu cggcgcgcag ggaccgaagg gugguagugg gucggguccg     1920

acgaucgagg agguagacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  5630
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt10)

<400>  5630
gggagaaagc uuaccauggc gaaggcggcg gcaauaggga uagacuuagg uacgacguac       60

ucgugcguug guguauucca gcacgguaag guagagauaa uagcgaacga ccaggguaac      120

cggacgacgc cgaguuacgu cgcguucacc gacacggagc gcuugaucgg ggacgccgcg      180

aagaaccagg uagcuuuaaa cccacaaaac acgguuuucg acgcaaagcg acucauaggg      240

cgaaaguucg gggaccccgu cguacaauca gacaugaagc acuggccguu ccaggucaua      300

aacgacggug acaagccgaa gguccaggua aguuacaagg gcgagacgaa ggcguucuac      360

ccugaggaga ucucaaguau gguauugacg aagaugaagg agauagcgga ggcauacuua      420

ggauaccccg ugacgaacgc cguaaucacg guccccgcgu acuucaacga cucucagcgg      480

caggcgacga aggacgcagg cguaaucgca ggguuaaacg uauugcgcau cauaaacgag      540

ccgaccgcgg cggcgauagc auacggguua gaccggaccg ggaaggguga gcgaaacgua      600

uuaaucuucg acuugggugg ggguacguuc gacgucucga uauuaaccau cgacgacggc      660

auauucgagg uaaaggcgac cgccggggac acgcacuuag gcggggagga cuucgacaac      720

cgauugguca accacuucgu agaggaguuc aagcgaaagc acaagaagga cauaucgcag      780

aacaagcgug cgguaagaag guuacgaacg gcgugcgagc gggcuaagcg cacguuaagu      840

ucgaguacgc aggcgucguu ggagauagac aguuuauucg aggguauaga cuucuacacu      900

ucgauaacgc gugcacgauu cgaggaguua ugcucggacu uauucagguc gacguuagag      960

ccgguagaga aggcauuacg agacgcgaag uuggacaagg cacagauaca cgacuuagua     1020

uuaguaggug guucgacgcg gauaccgaag guacagaagu uguuacagga cuucuucaac     1080

ggucgagacu uaaacaaguc gaucaacccg gacgaggcgg uagcguacgg ggccgcggua     1140

caggccgcga uauugauggg ugacaagagu gagaacguac aggacuuauu auuauuagac     1200

guagcacccu uaucuuuggg uuuagagacc gcgggugggg ucaugacggc guuaauaaag     1260

cgaaacucga cgaucccgac gaagcagacc cagaucuuca cuacguacuc ggacaaccag     1320

ccggguguau ugauccaggu auacgagggu gagcgagcga ugaccaagga caacaacuua     1380

uuaggacguu ucgaguuguc ggguauaccg cccgcaccuc gagggguccc gcagaucgag     1440

gucacguucg acaucgacgc gaacgguauc uuaaacguaa cggcgaccga caaaaguacg     1500

gggaaggcca acaagaucac gauaacgaac gacaaggguc gauuaucgaa ggaggagaua     1560

gagaggaugg uccaggaggc agagaaguac aaggccgagg acgaggucca gagagagcga     1620

guaagugcga agaacgcguu ggagucguac gcguucaaca ugaagagugc ggucgaggac     1680

gaggguuuaa aggguaagau cucggaggcc gacaagaaga aggucuuaga caagugccag     1740

gagguuauau cuugguuaga cgcgaacacg uuagcggaga aggacgaguu cgagcacaag     1800

cgcaaggagu uagagcaggu augcaacccg auaauaucgg guuuguacca gggggcgggc     1860

gggccggguc cgggugguuu cggcgcgcag ggaccgaagg gugguagugg gucggguccg     1920

acgaucgagg agguagacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  5631
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt10)

<400>  5631
gggagaaagc uuaccauggc gacggcgaag gguauagcua uagguauaga cuuaggaacg       60

acauacucgu gcguaggugu cuuccagcac gggaaggucg agaucauagc uaacgaccag      120

gggaacagga caacgccgag uuacgucgcg uucaccgaca cugagagauu gaucggugac      180

gcggcgaaga accaggucgc gaugaacccu caaaacacgg uauucgacgc gaagcgguua      240

aucggucgca aguucaacga cccggucguu caggcggaca ugaaguuaug gccguuccaa      300

guaauaaacg agggcggaaa gccgaaggua uugguaucgu acaaggguga gaacaaggca      360

uucuacccgg aagagauaag uucgaugguu uuaaccaagu uaaaggagac agcggaggcg      420

uucuuagguc auccgguaac uaacgcggua aucacgguac ccgcuuacuu caacgacagu      480

cagcggcagg cgacgaagga cgcggggguc auagcggguu uaaacguauu acgcauaaua      540

aacgagccaa cggcagcggc gauagcguac ggucuugaca aggggggaca gggugagcgg      600

cacguauuaa ucuucgacuu agguggcggu acauucgacg ucucgauauu gacgaucgac      660

gacgguauau ucgagguaaa ggcgacggcg ggugacacgc acuuaggugg ugaggacuuc      720

gacaacagau uaguaaguca cuucgucgag gaguucaagc ggaagcacaa gaaggacaua      780

ucgcaaaaca agcgcgcugu aaggagauug cggacggccu gcgagcgcgc gaagcggacg      840

uuaaguucgu cgacgcaggc gaaccucgag auagacucgu uguacgaggg uauagacuuu      900

uacacgagua ucacgcgagc gagauucgag gaguuaugcg ccgacuuauu ccgcgggaca      960

uuggagcccg uugagaaggc guuaagggac gcgaagaugg acaaggcgaa gauccacgac     1020

auaguauuag ucggugguuc gacccgaaua ccgaagguac agcgguuauu acaagacuac     1080

uucaacgguc gcgacuugaa caagucgaua aacccggacg aggcgguagc guacggggcg     1140

gcaguccagg cggcgauauu aaugggggac aagucggaga agguccaaga cuuauuauug     1200

uuggacguug cgccguuaag uuuagguuua gagacugcgg gcgguguaau gacggcguua     1260

aucaagcgga acucgacaau accaacgaag cagacgcaaa uauucacuac guacagugac     1320

aaccagccgg guguauugau acagguauac gagggugagc gggcgaugac gaaggacaac     1380

aacuuauuag gucguuucga cuuaacuggu auaccuccgg cuccgcgggg gguaccgcaa     1440

auagagguca cguucgacau agacgcgaac gggaucuuaa acguaacggc gaccgacaag     1500

ucgacaggua agguuaacaa gauaacuaua acgaacgaca aggguagauu aucgaaggag     1560

gagaucgaga ggauggucuu ggacgcggag aaguacaagg cagaggacga gguacagaga     1620

gaaaagauag cggcgaagaa cgcguuagag aguuacgcgu ucaacaugaa gucgguagua     1680

ucggacgagg gauuaaaggg uaagaucucg gagagugaca agaacaagau auuagacaag     1740

ugcaacgagu uauuaucgug guuggagguu aaccaguuag cggagaagga cgaguucgac     1800

cauaagagga aggaguuaga gcaaaugugc aacccgauca ucacgaaguu auaccagggg     1860

gguugcacgg guccggcgug cgguacgggu uacgucccug ggcgaccggc aacagguccg     1920

acgauagagg agguagacug aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  5632
<211>  2137
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt10)

<400>  5632
gggagaaagc uuaccauguc ggccaggggg ccggccauag ggaucgauuu ggggacgacg       60

uauagcugug ucggggucuu ucaacauggg aagguggaga ucauagccaa ugaucagggc      120

aaucgcacga ccccgaguua cgucgcguuc accgauacgg agagguugau aggggaugcc      180

gcgaaaaauc aagucgccau gaauccgacc aauaccauau uugaugccaa acgcuugaua      240

gggaggaaau uugaggaugc caccgugcag ucggauauga aacauuggcc guuuaggguc      300

gucagugagg gggggaagcc gaaaguacag guggaguaua agggggaaac caaaacguuc      360

uuuccggagg aaauaagcuc gauggucuug acgaagauga aggagaucgc cgaagccuac      420

uuggggggga aagugcauuc ggccgucauc accgugccgg ccuauuucaa ugauucgcag      480

cgccaggcca ccaaggaugc cgggacgauc accggguuga auguguugag gaucauaaac      540

gagccgaccg ccgccgccau agccuauggg uuggauaaaa aggggugugc ggggggggaa      600

aagaaugugu ugaucuuuga uuuggggggc gggaccuuug augugagcau cuugacgauc      660

gaggauggga uauuugaagu gaagucgacc gcgggggaua cccauuuggg gggcgaggau      720

uuugauaaua ggauggucuc gcacuuggcg gaggaauuua agcgcaaaca uaaaaaggac      780

aucgggccga auaagagagc cguccgccgc uugcgcacgg ccugugagag agccaagcgc      840

acguugucga gcucgaccca ggccucgauc gagauagaua guuuguauga gggcgucgau      900

uuuuauacga gcauaaccag agcgagguuc gaagaguuga augcggacuu auuuaggggg      960

accuuggagc cgguggagaa ggccuugagg gaugccaagc ucgauaaggg gcagauccag     1020

gagaucgugu uagugggggg gaguacgagg auaccgaaga uacagaaguu guugcaggau     1080

uuuuuuaaug gcaaggaguu gaauaagagc aucaauccgg acgaggccgu ggcguauggg     1140

gccgccgucc aggccgccau cuugauaggc gauaagucgg aaaaugugca ggauuuguug     1200

uuauuggaug ucacgccguu gagcuugggc aucgaaaccg ccgggggggu caugacgccg     1260

uuaaucaaga ggaauaccac gaucccgacc aagcaaacgc aaacguuuac cacguauucg     1320

gauaaucaaa gcagugucuu ggugcaaguc uaugaagggg agagggccau gaccaaggau     1380

aauaauuugc ucgggaaauu ugauuugacc gggauccccc cggccccgag gggggucccg     1440

cagauagagg ugaccuucga uaucgaugcg aaugggauau ugaaugucac ggccgcggau     1500

aagucgaccg gcaaagagaa uaaaauaacc aucaccaaug auaagggccg cuuaucgaag     1560

gaugauaucg auaggauggu gcaggaggcc gagagguaua agagcgagga cgaagccaau     1620

cgcgauaggg uggccgccaa aaaugccuua gagagcuaua cguauaauau aaaacaaacg     1680

guggaggaug agaaguuaag ggggaagauc ucggagcagg auaagaauaa gaucuuagau     1740

aagugccagg aggugaucaa uugguuggau aggaaucaga uggcggagaa ggaugaguau     1800

gagcauaagc agaaggaguu ggagaggguc uguaauccga ucauaagcaa gcucuaucag     1860

ggggggccgg gggggggcuc gggggggggg gggagugggg ccucgggggg gccgacgaua     1920

gaggaggucg acugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1980

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2100

ccccccccca aaggcucuuu ucagagccac cagaauu                              2137


<210>  5633
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt10)

<400>  5633
gggagaaagc uuaccauguc agucguaggu aucgaccucg guuuucaaag uuguuacgua       60

gcgguagcgc gagcuggagg uauagagacg auagcaaacg aauacucgga ccgaugcacu      120

ccugcgugca uaucguucgg gccgaagaac aggucgauag gggccgcggc aaagucgcag      180

guuaucucaa acgcgaaaaa cacgguacag gguuucaagc gauuucacgg ucgugcguuc      240

ucggacccuu ucgucgaggc cgagaagagu aacuuagcgu acgacauagu ucaauuaccg      300

acgggucuca cgggcauuaa gguaacuuac auggaagagg agcgcaacuu cacuacggag      360

cagguaacgg cgauguuguu aucgaaguua aaggaaacgg cagagucggu auuaaagaag      420

ccagugguag acugcguagu aucaguaccg ugcuucuaca cggacgcgga gcggcguucg      480

guuauggacg ccacgcagau agcggggcuc aacuguuuac gccuaaugaa cgagacgacg      540

gccguagcgu uagcguacgg gauuuacaag caggacuugc cagcgcuuga ggagaagccg      600

cgcaacguug uauucgugga caugggacac ucggcauacc aggugucggu cugcgcguuc      660

aaccggggga agcucaaggu cuuagcgacg gcguucgaca ccacguuagg cggacgcaag      720

uucgacgagg uacucguuaa ccacuucugc gaggaguucg guaagaagua uaaguuagac      780

auaaagucga agauucgagc guugcuucgu uuaucgcagg agugcgagaa guuaaagaag      840

uuaaugucag cgaacgcguc ggacuugccc cuuucgaucg agugcuucau gaacgacgua      900

gacguuucag ggaccaugaa cagggggaag uucuuagaga uguguaacga cuuauuggca      960

cgagucgaac cucccuugag gucggucuua gagcagacaa aguugaagaa ggaggacaua     1020

uacgcgguag agaucgucgg aggggcaacg cguauuccgg caguuaagga gaagauaucg     1080

aaguucuucg gcaaggaguu aucgacgacg cuuaacgcgg acgaggcggu aacgaggggu     1140

ugcgcguuac agugcgcuau acuuucucca gcguucaagg uacgcgaguu cucgauaacg     1200

gacguuguuc cguaccccau caguuuacgg uggaacucgc cggcggagga ggguucgucg     1260

gacugcgagg uguucucgaa gaaccacgcg gcgcccuucu cgaaggucuu aacguucuac     1320

cgaaaagagc cguucacauu agaggcauac uacaguucgc cacaggaccu uccuuacccg     1380

gacccggcga ucgcacaguu cucgguacaa aagguuacgc cccagucgga cgguucgucg     1440

ucgaagguca agguaaaggu gaggguuaac guucacggua ucuuuucggu caguucggcg     1500

ucgcuuguag agguccacaa gucggaggag aacgaggagc cgauggagac ggaccagaac     1560

gcgaaagagg aggagaaaau gcagguagac caggaggagc cgcacguaga ggagcagcaa     1620

cagcagacgc cggcggagaa caaggcggag ucggaggaga uggagacuuc gcaggcgggc     1680

ucgaaggaca agaaaaugga ccagccuccg caggcgaaaa aggcgaaggu caagacaucu     1740

accgucgacu uaccgauaga gaaccaguua uuguggcaaa ucgaccgaga gauguuaaac     1800

uuauacaucg agaacgaggg gaaaaugauc augcaggaca aguuggaaaa ggagcgcaac     1860

gacgcgaaaa acgcgguuga ggaguacguu uacgagaugc gugacaaguu aucgggcgag     1920

uacgagaagu ucgucucgga ggacgaccga aacucauuca cguuaaaguu ggaggacacg     1980

gagaacuggu uauacgagga cggggaggac caaccgaagc agguauacgu cgacaagcua     2040

gcggagcuua agaacuuggg acagcccaua aagaucaggu uccaagagag ugaggagcgc     2100

ccgaagcuau ucgaggaguu agguaagcaa auacagcagu acaugaagau cauaucuagu     2160

uuuaagaaca aggaggacca auacgaccac uuagacgcgg cagacaugac uaaggucgag     2220

aagaguacga acgaggcgau ggaguggaug aacaauaagu uaaacuuaca aaacaagcag     2280

ucguuaacga uggacccggu aguaaagucg aaggagaucg aggccaagau caaggaguua     2340

accucuacau gcucgccaau cauaucgaag ccgaagccga agguagagcc gccgaaggag     2400

gagcagaaga acgccgagca aaacggcccc guagacgguc agggugacaa ccccgggccu     2460

caggcggcag aacaggggac ggacaccgcg guaccgucug acucggacaa aaaguuaccg     2520

gagauggaca ucgacugagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  5634
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt10)

<400>  5634
gggagaaagc uuaccaugag cgucgucggg aucgauuugg gguucuugaa uuguuauaua       60

gccguggccc gcucgggggg gauagaaacg auagcgaacg aauauucgga ucgcuguacg      120

cccgcgugca ucagccucgg gagccgcacc agggcgauag ggaacgccgc caaaucgcaa      180

aucgugacca auguccgcaa caccauccac ggguuuaaga aauugcacgg caggagcuuc      240

gacgauccga ucguccagac cgagcgcaua cgcuugccgu acgaauuaca aaagaugccg      300

aacgggucgg ccggggucaa agucagauau cucgaagagg aacgcccguu cgccaucgaa      360

caagucaccg ggauguuacu cgcgaaauug aaggaaacca gcgagaacgc ccucaaaaag      420

ccggucgccg auugcgucau cagcaucccg ucguuuuuca ccgacgcgga acgccgcagc      480

gucauggccg ccgcgcaagu cgccgggcuc aacugccucc gccucaugaa cgagaccacc      540

gccgucgccu uagccuacgg gaucuacaag caagacuugc cgccgcucga cgaaaagccg      600

cgcaacgucg ucuucaucga cauggggcau agcgcguacc aagugcucgu cugcgccuuu      660

aauaaaggga aguugaaggu gcucgccacc acguucgacc cguaccucgg ggggcgcaau      720

uucgacgaag cccucgucga uuauuuuugc gacgaauuua aaacgaagua caaaaucaac      780

gucaaggaga auagcagagc gcuccucagg cucuaccaag aaugcgagaa guugaaaaaa      840

uugaugucgg ccaacgccag cgacuugccg cucaauaucg aaugcuuuau gaacgauuug      900

gacgucagcu cgaagaugaa ucgcgcccag uucgaacaau uaugcgccag uuugcucgcg      960

cgcgucgagc cgccgcucaa agccgucaug gagcaagcca aucuccaaag ggaggauauc     1020

ucgucgaucg agaucgucgg gggggccacc aggaucccgg ccgucaagga gcaaauaacc     1080

aaguuuuucu ugaaggauau cucgacgacc cucaacgccg acgaggccgu cgcccgcggg     1140

ugcgcccucc aaugcgccau cuugagcccg gccuucaagg ucagggaguu caguaucacc     1200

gauuuggucc cguacagcau aacccuccgc uggaaaacga gcuucgagga cgggucgggc     1260

gagugcgagg ucuuuugcaa aaaucauccg gcgccguuua gcaaagugau caccuuucau     1320

aaaaaagagc cguucgaguu ggaggccuuc uacaccaacc uccaugaggu cccguauccg     1380

gacgcccgca ucggcucguu uaccauccaa aacgucuucc cgcaaagcga cggggacucg     1440

aguaagguca aagucaaggu cagggucaau auacacggga uauuuucggu cgccucggcc     1500

agcgucaucg aaaaacagaa ccucgagggg gaccauucgg acgccccgau ggaaaccgag     1560

accagcuuca agaacgagaa uaaggacaac auggacaaga ugcaagucga ccaagaggag     1620

ggccaccaga agugccacgc cgagcauacc ccggaggaag agaucgacca uaccggggcg     1680

aagaccaaaa gcgccgugag cgauaagcaa gauaggcuca accaaaccuu gaagaagggg     1740

aaaguaaagu cgaucgacuu gcccauacaa ucgucguugu gccgccaauu ggggcaagac     1800

uuguuaaauu cguauaucga gaacgaaggc aaaaugauaa ugcaagacaa acucgaaaag     1860

gagcgcaacg acgccaaaaa cgcggucgag gaguacgucu acgacuuccg cgaucgcuua     1920

gggaccgugu acgagaaguu uauaaccccg gaagaucucu cgaaauuaag cgccguccuc     1980

gaggauaccg aaaacugguu guacgaggau ggggaagauc aaccgaagca ggucuacguc     2040

gacaaauugc aggaguugaa aaaguauggg caaccgaucc aaaugaaaua uauggaacac     2100

gaagaacgcc cgaaggcgcu caacgaucuc gggaaaaaaa uacaauuggu gaugaaaguc     2160

aucgaagccu accgcaauaa agacgagcgc uacgaccacu uagacccgac cgaaauggag     2220

aaagucgaga agugcauauc ggacgcgaug ucgugguuaa acucgaaaau gaacgcccaa     2280

aauaaguugu cguugaccca ggacccgguc gucaagguca gcgagaucgu cgccaaaagc     2340

aaagaguuag acaacuuuug caauccgaua aucuauaaac cgaaaccgaa ggccgagguc     2400

ccggaggaua agccgaaggc caacucggaa cauaacgggc cgauggacgg gcaaucgggg     2460

accgagacca agagcgacag caccaaggau ucgagccaac acaccaaaag uagcggggaa     2520

auggaggucg auugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  5635
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt10)

<400>  5635
gggagaaagc uuaccaugaa auugaguuua gucgcggcca uguuauuauu auugucggcc       60

gccagagcgg aagaagaaga uaaaaaagaa gaugucggga ccgucguggg gauagauuua      120

ggcacgacgu auaguugugu gggggucuuu aaaaauggga gggucgaaau aauagcgaau      180

gaccaaggga auaggauaac ccccaguuac guggcguuua ccccggaggg cgagagguua      240

aucggggacg cggcgaaaaa ucaauugacg aguaauccgg aaaauaccgu guucgaugcg      300

aaaagauuga uagggaggac cuggaacgau cccagcgucc aacaagauau aaaauuucuc      360

cccuuuaaag ucgucgagaa aaagaccaag ccguauaucc aggucgacau cggggggggc      420

cagaccaaaa ccuucgcccc ggaggagauc agcgcgaugg ucuugaccaa gaugaaggag      480

acggccgaag ccuaccucgg gaaaaaaguc acgcacgccg ucgucaccgu cccggcguac      540

uucaacgacg cgcagaggca ggccacgaag gaugccggga ccaucgccgg guugaacguc      600

augcgcauaa uaaaugaacc gaccgccgcc gccaucgccu acggguuaga caaacgcgaa      660

ggcgaaaaaa auauauuagu cuucgauuua ggggggggga cguuugacgu cagcuuguug      720

acgaucgaua acgggguguu ugaggucguc gcgaccaacg gggacaccca cuuagggggg      780

gaggauuucg aucaaagggu gauggagcau uuuauaaagu uauauaagaa aaaaaccggg      840

aaggacgugc gcaaggauaa ccgcgccguc caaaaguuga gaagggaagu cgagaaagcg      900

aagagagcgu uaagcagcca acaccaggcc cgcaucgaga ucgaaaguuu uuacgagggg      960

gaggauuuca gcgaaacguu aaccagagcg aaguucgagg aauugaauau ggacuuauuu     1020

agaagcacca ugaaaccggu gcaaaagguc cucgaggaca gcgaccucaa aaaaagcgac     1080

aucgacgaga ucgucuuggu cggggggagc accaggaucc cgaaaaucca acaguuaguc     1140

aaggaauuuu uuaacgggaa agagccgagu agggggauca auccggacga ggccgucgcc     1200

uacggggccg ccgugcaagc cggggucuug agcggggacc aggacaccgg ggauuuaguc     1260

uuauuggacg ucugcccguu gaccuugggg aucgagaccg ucgggggggu gaugacgaag     1320

uuaaucccgc gcaauaccgu cgucccgacg aaaaaaagcc aaauauucag caccgccagc     1380

gacaaccagc cgaccgucac cauaaaagug uacgaggggg agcgcccguu aaccaaggau     1440

aaccacuugu uagggaccuu cgacuuaacc gggaucccgc cggccccgag gggcgugccg     1500

caaaucgagg ugacguucga aaucgacguc aacgggaucu ugagggucac cgccgaggau     1560

aaagggaccg gcaauaagaa caaaauaacc auaacgaacg aucaaaacag guuaaccccg     1620

gaggagauag agcgcauggu caacgacgcc gaaaaauucg ccgaagagga uaagaaauug     1680

aaagaaagga ucgacacccg caacgaacuc gagucguacg cguacagcuu gaaaaaccaa     1740

aucggggaca aggagaaauu aggggggaag uugaguagcg aggacaaaga aacgauggag     1800

aaggccgucg aggagaaaau cgagugguua gagucgcauc aggacgccga uaucgaggau     1860

uuuaaggcca aaaaaaaaga guuagaggag aucguccagc cgaucauauc gaaguuguac     1920

gggucggccg ggccgccgcc gaccggggag gaagacaccg ccgagaagga cgaacucuga     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  5636
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt10)

<400>  5636
gggagaaagc uuaccaugca agcgccgaga gaauuggccg ucgggauaga uuuagggacg       60

acguauagcu gugucggggu cuuccaacaa gggagggucg aaauauuagc gaaugaucaa      120

gggaauagga cgaccccguc guaugucgcg uuuacggaua cggaaagauu agugggcgau      180

gccgcgaaau cgcaagccgc guuaaauccg cauaauacgg ucuuugacgc gaaaagauua      240

auaggcagga aauuugccga uacgaccguc caaagcgaua ugaaacauug gccguuuaga      300

gucgucucgg aaggggggaa accgaaaguc agggucuguu auaggggcga agauaaaacc      360

uuuuauccgg aagaaauaag caguaugguc uuaucgaaaa ugaaagaaac cgcggaagcc      420

uauuuagggc aaccggucaa acaugccguc auaacggucc cggcguacuu uaacgauagc      480

caaaggcaag cgacgaaaga ugccggcgcg auagccggcu ugaauguccu cagaauaaua      540

aacgaaccga ccgccgccgc gauagcguac ggcuuagaua gaagaggggc cggggaaagg      600

aaugucuuga ucuucgauuu agggggcggg acguuugacg ucagcgucuu gaguaucgau      660

gccggggugu ucgaagucaa ggcgaccgcc ggggacacgc auuuaggggg ggaagauuuu      720

gauaauagau uggucaauca uuuuauggag gaguuuagaa gaaaacacgg caaagauuua      780

ucgggcaaua aaagggcguu aaggcgcuua aggaccgcgu gcgaaagggc gaaaaggacg      840

uuaaguaguu cgacgcaagc gacguuagaa aucgauaguu uauuugaagg ggucgauuuu      900

uauaccagua uaaccagggc gagguucgaa gaguuaugua gcgauuuguu uaggucgacg      960

uuagaacccg ucgaaaaagc guuaagagac gcgaaauuag auaaagcgca aauccacgau     1020

gugguguuag ucggcgggag uaccaggaua ccgaaagucc aaaaacucuu acaagauuuu     1080

uuuaauggga aagaauuaaa uaaaucgaua aauccggacg aagccgucgc guacggcgcc     1140

gccguccaag ccgcgguccu caugggcgau aagugcgaaa agguccaaga cuuguuauua     1200

uuagacgucg ccccgcucag cuuaggcuua gaaaccgccg ggggcgucau gacgaccuua     1260

auacaacgca augcgaccau accgacgaaa caaacgcaaa ccuuuacgac guauagcgau     1320

aaucaaccgg gcguguuuau acaagucuac gaaggggaac gcgcgaugac gaaagauaau     1380

aauuuauuag gcagguucga guugucgggg auaccgccgg cgccgagggg ggugccgcaa     1440

aucgaaguca ccuucgauau cgacgccaac gggauauuau cggucaccgc gaccgaucgc     1500

ucgaccggga aagccaauaa aauaacgaua acgaacgaua aagggagauu aucgaaagaa     1560

gaagucgaac gcauggucca cgaggcggaa caauauaaag ccgaagacga agcgcaacgc     1620

gaucgcgucg ccgcgaagaa uagcuuagaa gcgcacgugu uucacgucaa ggggagccuc     1680

caggaagagu cguugcgcga uaaaaucccg gaggaagauc gcaggaagau gcaggauaaa     1740

ugcagagagg uguuggcgug guuagaacau aaucaauuag ccgaaaaaga agaauacgaa     1800

caccaaaaac gcgaauuaga acagauaugc aggccgauau uuagucgcuu guacggcggc     1860

ccgggggugc cgggcggguc gucgugcggg acccaggcga ggcaaggcga uccgucgacg     1920

gggccgauaa ucgaagaagu cgacugagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  5637
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt10)

<400>  5637
gggagaaagc uuaccaugca ggcgccccgc gagcuggccg ugggcaucga ccucgggacc       60

accuacagcu gcgucggcgu guuccagcag gggcgggugg agauccuggc caacgaccag      120

ggcaaccgca cgaccccguc cuacgucgcc uucaccgaca ccgagcggcu ggugggggac      180

gccgccaagu cgcaggccgc gcucaacccc cacaacacgg uguucgacgc caagcgcuua      240

aucggccgga aguucgccga caccaccguc cagagcgaca ugaagcacug gcccuuccag      300

guggugucgg agggcgggaa gcccaagguc agggugugcu accggggcga ggacaagacc      360

uucuacccgg aggagaucag cagcauggug uuauccaaga ugaaggagac ggccgaggcg      420

uaccucgggc agcccgucaa gcacgccgug aucaccgugc ccaccuacuu cucgaacagc      480

cagaggcagg ccaccaagga cgccggcgcc aucgcggggc ugaaggucuu acccaucauc      540

aacgaggcca cggccgccgc caucgcguac ggccucgaca gacgcggcgc cgggaagcgg      600

aacgugcuga ucuucgacuu aggcgggggc accuucgacg ugagcgucuu gaguaucgac      660

gccggcgugu ucgaggugaa ggccaccgcc ggggacaccc acuuaggcgg ggaggacuuc      720

gacaaccgcc uggucaacca cuucauggag gaguucagac gcaagcacgg caaggaccuc      780

ucggggaaca agcgggcguu aaggcgguua aggacggccu gcgagcgggc caagaggacc      840

ccgaguagcu ccacccaggc cacccucgag aucgacagcu uauucgaggg cguggacuuc      900

uacaagagua ucacgcgggc cagguucgag gaguuaugca gcgacuuguu cagguccacc      960

uuagagcccg uggagaaggc guuaagagac gccaagcucg acaaggccca gauccacgac     1020

uucgucuuag gcgggggccu gcacagccac ccccaggggg ccgagguggc ggccggccuc     1080

cugcagcgcc agggggccga gcaggagcac cagcccugag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  5638
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt10)

<400>  5638
gggagaaagc uuaccauguc gaaggggccg gcgguaggua uagacuuagg cacgacguac       60

ucgugcguag ggguauucca gcacggcaag guagagauca ucgcgaacga ccaggggaac      120

cgaacaacgc cgucguacgu agcauucacc gacacggagc gcuuaauagg cgacgcggcg      180

aagaaccagg uagcgaugaa cccgacuaac acggucuucg acgcgaagcg guuaaucggu      240

cgacgguucg acgacgcggu aguacagucg gacaugaagc acuggcccuu cauggucguu      300

aacgacgcag guagaccgaa gguacaggug gaguacaagg gcgagaccaa gucguucuac      360

ccggaggagg ucucgucgau gguguuaacc aagaugaagg agaucgcgga ggcguacuug      420

gguaagacgg ugacgaacgc agucguuacg gucccggcgu acuucaacga cagucagcga      480

caggcgacua aggacgcggg uacgaucgcg ggauuaaacg ucuuacgaau caucaacgag      540

ccgacggcgg ccgcgauagc guacgggcua gacaagaagg uaggugcgga gaggaacgua      600

uuaaucuucg acuugggggg cgggacguuc gacguaucga uauuaaccau cgaggacggu      660

auuuucgagg uaaagaguac cgcaggggac acccacuuag ggggggagga cuucgacaac      720

cguaugguaa accacuucau agcggaguuc aagcggaagc acaagaagga cauaucggag      780

aacaagcgcg ccguacgacg uuuacggacg gcgugcgaga gagcgaagcg aaccuuaagu      840

ucgaguacuc aggcaucgau agagauagac ucguuauacg aggggaucga cuucuacacg      900

ucgaucacgc gagcgcgguu cgaggaguug aacgccgacu uguuccgagg gacgcuugac      960

ccgguggaga aggcguuacg ggacgcuaag uuagacaaga gucagauaca cgacauagua     1020

uuaguagggg ggucgacgcg aaucccuaag auacagaagu uauugcagga cuucuucaac     1080

ggcaaggagu uaaacaagag uauaaacccg gacgaggcag uagccuacgg ggcggcggua     1140

caggcggcga uucucucggg ugacaagucg gagaacgugc aggacuuauu auuauuagac     1200

guaacgcccu uaucgcucgg gaucgagacg gcgggggggg uaaugacggu auugaucaag     1260

aggaacacga cgauaccgac gaagcaaacg cagacguuca cgaccuacuc ggacaaccag     1320

ccgggcguau uaauacaggu auacgagggc gagcgggcca ugacgaagga caacaaccuu     1380

uuagguaagu ucgaguuaac ggguauuccg ccggcgccga gggggguacc gcaaaucgag     1440

guaacguucg acauagacgc gaacgggauc cuuaacguaa gugcgguaga caagucgacg     1500

gguaaggaga acaagaucac gauaacgaac gacaagggcc gcuuaaguaa ggaggacauc     1560

gagcgcaugg uacaggaggc ggagaaguac aaggcggagg acgagaagca gcgagacaag     1620

guaucgucga agaacucguu ggagaguuac gcguucaaca ugaaggcgac gguagaggac     1680

gagaaguuac aggguaagau caacgacgag gacaagcaga agaucuugga caagugcaac     1740

gagauaauca acugguuaga caagaaccag acggcggaga aggaggaguu cgagcaccag     1800

caaaaggagu uagagaaggu augcaacccg aucauaacga agcuauacca guccgcgggu     1860

gggaugccgg gggggaugcc gggcgguuuc cccggagggg gugccccgcc gagugggggg     1920

gcgucgucgg gcccgacgau cgaggagguc gacugaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  5639
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt10)

<400>  5639
gggagaaagc uuaccaugau cucggcgucg agggccgccg ccgcgagguu ggucggggcg       60

gccgcgagua gagggccgac cgcggcgagg caucaagacu cguggaacgg guugucgcac      120

gaagccuucc gcuuggucag ccgcagagac uacgccagcg aggcgauaaa aggggccguc      180

gucgggaucg aucucgggac cacgaauagu ugugucgccg ucauggaggg gaagcaagcg      240

aaagucuuag aaaacgcgga gggggcgcgc acgacgccga gcgucgucgc guucaccgcc      300

gacggggaaa gguuggucgg gaugcccgcg aaaaggcaag ccgugacgaa uccgaauaau      360

accuucuacg ccacgaaaag guugaucggg agaagguacg acgacccgga gguccaaaag      420

gauaucaaga acgucccguu uaagaucgug agggcgagua acggggacgc gugggucgaa      480

gcccauggca agcucuacag ccccucgcaa auaggggccu ucguccucau gaaaaugaag      540

gaaaccgccg agaacuaucu cggccauacc gccaagaacg ccgucauaac cgugccggcc      600

uacuuuaacg auagccaacg ccaagcgacc aaagacgccg ggcaaauuag cggguuaaac      660

gucuugagag ucaucaacga accgaccgcc gccgccuugg cguacggguu ggauaagagc      720

gaggauaagg uaaucgccgu cuacgaccuc ggggggggga ccuucgacau cagcauauua      780

gagauccaaa agggggucuu cgaagucaag aguaccaacg gcgacacguu ucucgggggc      840

gaggauuucg aucaagcgcu cuugagacau aucgucaaag aauuuaaacg cgaaaccggc      900

gucgaccuca ccaaagauaa uauggccuug caacgcguca gagaggccgc cgagaaagcc      960

aagugcgagu ugaguagcag cguccaaacc gauauaaacc ucccguacuu gaccauggac     1020

agcagcgggc cgaaacaccu caacaugaaa cucacgaggg cccaguucga gggcaucgug     1080

accgacuuga uacgccgcac cauagccccg ugucaaaagg ccaugcagga cgccgaggua     1140

ucgaaaucgg auaucgggga ggucauauug gucgggggga ugacccgcau gccgaaaguc     1200

caacaaaccg uccaagauuu guucgggcgc gcgccgucga aagccgugaa cccggacgaa     1260

gccgucgcga ucggggccgc gauccaaggg gggguccucg cgggggacgu gaccgacguc     1320

uuauuguugg acgugacccc gcucagcuua gggaucgaga ccuugggggg gguguucacg     1380

aaguugauca accgcaacac gaccaucccg acgaaaaaau cgcaagucuu uagcaccgcg     1440

gccgacgggc agacccaggu cgagaucaag gucugucaag gggagcgcga aauggccggg     1500

gauaauaagu uguuggggca auucacccuc aucgggaucc cgccggcgcc gagggggguc     1560

ccgcaaaucg aggucaccuu cgauaucgac gcgaacggca ucguccacgu cagcgccaag     1620

gacaagggga ccgggaggga acaacaaauc gucauacaaa gcagcggggg gcucucgaag     1680

gacgacaucg agaacauggu caaaaacgcc gaaaaauacg ccgaggagga uagaaggaaa     1740

aaagagaggg ucgaggcggu caauauggcc gaggggauaa uccaugauac cgaaacgaaa     1800

auggaagagu uuaaagauca gcucccggcc gacgaaugua auaaauuaaa ggaggaaauc     1860

aguaagaugc gcgaauuguu agcccgcaaa gauucggaaa ccggggagaa cauccgccaa     1920

gccgcgagua gcuugcaaca agccagcuua aaauuauuug agauggccua uaaaaaaaug     1980

gccagcgaaa gggaggggag cgggucgagc gggaccggcg agcaaaaaga ggaccagaaa     2040

gaagagaaac aaugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  5640
<211>  2245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt10)

<400>  5640
gggagaaagc uuaccauggc agacaaggaa gcaggggguu cggacggccc ucgugagacu       60

gcaccuacuu cggcguacuc uucgccggcu cgaucguuag gugacacugg gaucacgccg      120

uuaaguccgu cgcacauagu aaacgauacg gacaguaacg uaucggagca gcagucguuc      180

uuaguaguag uagcggugga cuucgguacc acgucgucgg guuacgcgua cucguucacg      240

aaagagccgg agugcauaca cgucaugcgg aggugggagg ggggagaccc gggcguaagu      300

aaccagaaga caccuacgac gauauuauua acgccggagc ggaaguucca cucguucggu      360

uacgcggccc gugacuucua ccacgacuua gacccaaacg aggcaaagca augguuauac      420

uuggagaaau ucaaaaugaa guuacacacu acgggagacu uaacgaugga cacugacuug      480

acugccgcga acgguaaaaa gguaaaggcg cucgagaucu ucgcguacgc auuacaguac      540

uucaaggagc aggccuuaaa ggagcucucu gaccaggcug ggucagaguu cgagaacagu      600

gacguaaggu ggguaauaac uguaccggcg auauggaagc agccagcgaa gcaguucaug      660

cgccaggcag cguaccaggc gggguuagcg ucgccggaga acagugagca guuaauaauc      720

gcuuuagaac cggaagcggc gucgauauac ugccggaagu uacguuuaca ccaaaugaua      780

gaguuaucaa guaaggcggc gguuaacggg uacucagguu cggacacugu uggggcgggu      840

uucacgcagg cgaaggagca cauccgacga aacaggcaau cgcgcacauu ccucgucgag      900

aacguuauug gcgagauuug gagugagcuu gaggagggag acaaguacgu aguaguagac      960

ucgggugggg gaacuguuga uuuaacggua caccaaauua ggcucccaga gggucacuua     1020

aaggagcucu acaaggccac gggugguccg uacgguaguc ucgggguuga cuacgaguuc     1080

gagaaguugc ucuacaagau cuucggugag gacuucauag agcaguuuaa gaucaagcgu     1140

ccggcggcgu ggguagaccu caugauagcu uucgaaucgc gaaagcgcgc cgcagcgccg     1200

gaccgaacga acccuuugaa caucacguua ccguucucgu ucauagacua cuacaagaag     1260

uuccguggac acucgguaga gcacgcguua cgaaagagua acguagacuu cguaaagugg     1320

ucgagucagg guaugcuucg caugucgccc gacgcgauga acgcguuauu caagccuacu     1380

aucgacucga uaauagaaca cuugagggac uuauuccaga agccggaggu aucgacggua     1440

aaguucuuau ucuuagucgg gggguucgca gaggcgccgu uguuacagca ggcaguucag     1500

gcggcguucg gugaccagug ccgaauaaua auaccccagg acguaggguu aacgaucuug     1560

aagggggcgg uuuuauucgg guuagacccg gccguaauaa agguucgacg uucacccuug     1620

acuuacggug ucggcgucuu aaaccgauac guagagggga agcacccacc ggaaaaguug     1680

uuagucaagg acggaacacg auggugcacg gacguauucg acaaguucau aucggccgac     1740

caaaguguag cguuaggcga guuaguaaag cgaucguaua cgccugccaa gccgucgcaa     1800

uuaguaauag ucaucaacau cuacaguucg gagcacgaca acguaaguuu uauaacggac     1860

ccgggaguca agaagugcgg aacauuaagg uuagacuuga cggguacguc ggguaccgcg     1920

guuccagcgc gccgagagau acagacgcuc augcaguucg gugacacgga gauaaaggcg     1980

acggcgauag acaucgcuac gucuaagucg guaaaggucg guaucgacuu ucucaacuac     2040

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     2100

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2220

ggcucuuuuc agagccacca gaauu                                           2245


<210>  5641
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt10)

<400>  5641
gggagaaagc uuaccauguu agcaguaccc gagaugggau uacaagguuu auacauaggu       60

ucgucgcccg agcguucgcc gguuccgucg ccuccggggu cgccacgcac gcaagagucg      120

ugcgggauag caccuuuaac uccuucccag aguccuaagc cggaaguucg ugcaccgcag      180

caggcaucgu ucagugucgu agucgcuaua gacuucggua caacaucguc ggguuacgcc      240

uucucguucg cuucggaccc ggaggcaauc cauaugaugc guaaguggga ggguggugac      300

ccuggugucg cgcaccaaaa gacgccuacg ugcuuauuau uaacgccuga gggggcguuc      360

cacucguucg gauacacggc gcgagacuac uaccacgacu uggaccccga ggaggcucgc      420

gacugguuau acuucgaaaa guucaaaaug aagauacacu cggcgacuga cuuaacguua      480

aagacacaac ucgaggcggu uaacgggaag acaaugccgg cguuagaggu cuucgcgcac      540

gcguugaggu ucuuccgcga gcacgcgcuc caggaguuac gagagcaauc gccgucauug      600

ccggagaaag acacgguccg uugggucuua accgucccgg cgaucuggaa gcaaccggcg      660

aaacaguuca ugcgagaggc ggcuuauuua gcgggguuag uaucgcguga gaacgcggag      720

caauuauuaa uagcguuaga gccggaggcg gcgucaguuu acugucgaaa guugcgauug      780

caccaguugu uagauuuauc aggaagggcg ccgggaggcg ggcgauuggg cgagaggcga      840

ucgauagacu cgucguuccg acaggcgcgc gagcagcucc gucguucgag gcauucgcgg      900

acguucuuag uagagucggg uguuggugag uuaugggcgg aaaugcaggc gggugaccgu      960

uacguagucg cugacugcgg uggggggacg guagacuuaa caguucacca guuagagcag     1020

ccacacggua cguugaaaga gcuuuacaag gcgucaggag ggccguacgg ggccguaggg     1080

guugauuuag cguucgagca guugcucugc cggaucuucg gcgaggacuu caucgcaaca     1140

uucaagcgcc agcguccagc ggcauggguc gacuuaacaa uagcguucga ggcacguaag     1200

cggacggcag gaccgcaucg agcgggugca uuaaacauaa guuuaccguu cucguucaua     1260

gacuucuacc ggaagcaacg cggucacaac guagagacgg cgcucaggcg aaguucgguc     1320

aacuucguaa aguggaguuc gcaggguaug uugcgcauga guugcgaggc gaugaacgag     1380

uuauuccagc caacaguuuc aggcauuaua cagcacauug aggcauuauu ggcgcgcccc     1440

gagguacagg gggucaagcu cuuauucuug gucggaggau ucgcggaguc ggcaguauua     1500

cagcacgcag uacaagcggc uuuaggugcg aggggcuuac gcguaguagu accccacgac     1560

gucgguuuga cuauauugaa gggcgccguu uuauucgguc aggcuccggg agucgucagg     1620

guucgacggu cuccauuaac uuacgguguc gguguauuaa accguuucgu ccccgguagg     1680

cacccgccgg agaaguuauu gguacgagac ggucgaaggu ggugcacgga cguguucgag     1740

cguuucguag cagcggaaca gucagucgcg uuaggagagg agguaaggcg uucguacugu     1800

ccugcaaggc caggacagcg ucgagucuua auuaacuugu auuguugcgc agcggaggac     1860

gcacgauuca uaacugaccc ggguguacgg aagugcggug ccuuaaguuu ggaguuagaa     1920

ccggcggacu gcggucagga cacggcgggu gcaccaccgg gucgucgaga gauccgagca     1980

gcgaugcaau ucggugauac ugagauaaag gugacggcgg uagacguuuc gacuaacagg     2040

ucgguccgag caucgaucga cuucuuaucg aauugaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  5642
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt10)

<400>  5642
gggagaaagc uuaccauggc gcgcgaaaug acuauacucg ggucugcggu cuuaacguua       60

cucuuagcag guuacuuagc gcagcaguac cuuccucuuc cgacacccaa gguaauagga      120

auagacuuag guacgacaua cugcaguguc ggaguauucu ucccgggaac ugguaagguc      180

aagguaauac cggacgagaa cggacacauc ucuaucccgu cgauggucuc guucacggau      240

aacgacguuu acgucgggua cgagucgguc gaguuagcgg acucuaaccc gcagaacacg      300

aucuacgacg cuaagcgauu caucgguaag auauucacgg cggaggaguu agaggcagag      360

auagguaggu acccguucaa ggucuugaac aagaacggga ugguagaguu cucaguaacc      420

ucgaacgaga cgaucacugu aagucccgag uacgucgguu cacguuuacu auuaaaguug      480

aaggagaugg cggaggcgua cuugggcaug ccgguagcga acgcaguaau aucggucccc      540

gccgaguucg acuuaaagca acgaaacucg acgaucgagg cggcgaacuu agcggggcuu      600

aagauccuuc gagugaucaa cgagccgacg gcggcggcga uggccuacgg guuacacaag      660

gccgacguau uccacgugcu ugucaucgac uuaggaggug ggacacucga cgucucgcuu      720

uugaacaagc aggguggaau guucuugacg cgugcgaugu cggguaacaa caaguugggu      780

gggcaggacu ucaaccagcg auuauuacag uacuuguaca agcaaauuua ccagacguac      840

gguuucgucc cgucacgaaa ggaagagaua caucgauuaa ggcaggcagu cgagauggua      900

aaguugaacu ugacguuaca ccagucggcg caauuaagug ucuuguuaac gguugaggag      960

caggaccgua aggagccgca cucgucggac accgaguuac cgaaggacaa guugucgucg     1020

gcugacgacc acaggguaaa cucggguuuc ggcagggguu uaucagacaa gaagucgggc     1080

gagucgcagg uacucuucga gacggagauc agucgaaagu uauucgacac guuaaacgag     1140

gacuuauucc aaaagaucuu aguuccgauc cagcagguuu uaaaggaggg ucacuuagag     1200

aagacggaga uagacgaggu ugucuugguc ggugguucga cgcgaauccc ccgaaucagg     1260

cagguaauac aggaguucuu cgggaaggac ccaaacacgu cggucgaucc ggacuuagcg     1320

guuguuaccg guguugcgau ucaggccggg auagacgggg guucguggcc guuacaggua     1380

ucagcgcucg agauaccgaa caagcacuug cagaagacga acuucaacug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  5643
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt10)

<400>  5643
gggagaaagc uuaccauggc cgcgauaggg guccauuuag gguguacgag cgcgugcguc       60

gcgguguaca aagacgggag agccgggguc gucgccaacg acgcggggga uagggucacc      120

ccggccgucg ucgccuauag cgagaacgag gaaaucgucg ggcucgccgc caagcagucg      180

cgcauccgca acaucagcaa uaccgucaug aaggucaaac aaauauuagg gcgcucgagu      240

ucggauccgc aggcgcaaaa guauauagcc gagucgaagu gccucgugau cgaaaagaac      300

ggcaagcuca gguacgagau cgacaccggg gaggagacca aguucgucaa uccggaggac      360

gucgcgcgcu uaauuuuuuc gaaaaugaag gagaccgccc acagcguccu cgggagcgac      420

gccaacgacg ucgucaucac cgugcccuuc gacuucgggg aaaaacagaa gaacgccuug      480

ggggaggccg cccgcgccgc cggguucaac guccucaggc ucauccauga acccagcgcc      540

gccuuguugg ccuacgggau cgggcaggau aguccgaccg ggaagucgaa cauccucguc      600

uuuaaauugg gggggaccag ucucagcuug ucggugaugg aggucaauuc ggggaucuac      660

agagucuuga gcacgaauac cgacgacaau auaggggggg cccauuuuac cgagacgcuc      720

gcccaauacu uggccagcga auuucagcgc aguuuuaagc acgacguccg cgggaacgcc      780

agggcgauga ugaagcucac caauucggcc gaggucgcca aacacagccu cagcacgcuc      840

gggucggcga auugcuuuuu ggauagccuc uacgaggggc aggacuucga cuguaacguc      900

agucgcgccc gcuucgaguu guugugcagc ccguuguuca acaaaugcau cgaggccaua      960

cgcggguugc ucgaccagaa cggguuuacc gccgacgaca uaaauaaagu cguguugugc     1020

gggggcagca gcaggauacc gaaauugcaa caauuaauca aggacuuguu uccggccguc     1080

gaauuguuga acagcauacc gccggacgag gucauaccga ucggggccgc caucgaggcc     1140

gggaucuuga ucggcaagga gaauuuacuc gucgaagaua gcuugaugau cgaaugcagc     1200

gcgcgcgaca uccucgucaa aggggucgau gagagcgggg cgucgcgcuu uaccgucuua     1260

uucccgagcg gcaccccgcu cccggccagg cgccagcaua cccuccaagc gccggggucg     1320

aucagcagcg ucuguuugga guuguacgaa agcgacggca aaaauagcgc gaaagaagag     1380

acgaaauucg cccaagucgu cuugcaagau cucgauaaga aggagaacgg gcucagggac     1440

auccucgccg ucuugaccau gaagcgcgac gggagccucc acgucaccug uaccgaccaa     1500

gaaaccggga agugcgaggc cauaagcauc gaaaucgcca gcugaggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  5644
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt10)

<400>  5644
gggagaaagc uuaccauguc cgugguagga cucgacgucg ggagccaaag cugcuacaua       60

gcgguagcca gggcaggcgg gauagagacg aucgccaacg aguucuccga ucgcugcaca      120

cccagcguca ucagcuuugg uucuaaaaac aggacuauag gaguggccgc gaaaaaccaa      180

caaauaaccc augcaaacaa caccgucagc aacuucaaac gauuccacgg acgugccuuc      240

aacgacccgu uuauacaaaa agaaaaagaa aaccuauccu acgaccuagu cccccucaag      300

aauggaggcg ugggcaucaa aguuauguau augggagaag aacacuuguu cucaguagaa      360

cagauaaccg ccaugcuacu aacaaaacug aaggaaaccg cagagaacag ucugaagaaa      420

ccugucaccg acugcguaau cuccguaccc uccuucuuca ccgacgcaga acggagaucc      480

guacuagacg cagcccaaau aguaggccua aacugccucc gcuugaugaa cgauaugacg      540

gccguagcac ucaacuaugg gauuuacaaa caagaccucc caagccucga cgaaaaaccc      600

cgcauaguag ucuucgucga caugggacac ucagcauucc agguaagcgc augcgccuuc      660

aacaaaggaa aacucaaagu cuuaggcacg gcuuucgacc ccuuccuagg cgggaaaaau      720

uucgacgaga aacucgucga acacuucugc gccgaguuca aaaccaaaua caaacucgac      780

gcaaagagca aaauccgagc ccuccuacgc uuauaccagg aaugcgaaaa gcuaaagaaa      840

uugauguccu ccaacuccac cgaccuaccc uuaaacaucg aauguuucau gaacgacaag      900

gacgucagcg gaaagaugaa cagaucccag uucgaggagc ucugcgccga guuauuacaa      960

aagauagaag ucccccucua cagccuucuc gaacagaccc accucaaagu agaagacguu     1020

ucagccgucg aaaucgucgg cggagcaaca cgcauccccg cggucaaaga acgcaucgcc     1080

aaauucuucg ggaaggacau auccaccacc cuaaacgcag acgaagcagu ggcacgcggg     1140

ugugcccucc agugcgccau cuuaagcccc gcauucaaag uacgagaguu cucaguaacc     1200

gaugccgucc cguucccaau aagccugaua uggaaccacg acagcgagga caccgaaggu     1260

guccacgaag ucuucagucg aaaccacgcg gccccauucu caaaaguauu aacguuccuc     1320

cgacgcggac ccuucgaacu cgaagcauuc uacagcgacc cgcaaggcgu accguacccu     1380

gaggcaaaga uuggcagguu cguaguccag aacgucuccg cacaaaaaga uggcgagaaa     1440

agccgcguaa aggucaaagu ccgagucaau acacacggaa ucuucaccau uuccaccgcc     1500

ucaaugguag aaaaaguccc cacagaagaa aacgagauga gcucugaagc cgacauggag     1560

ugccucaacc aacgcccacc cgaaaacccc gacaccgaca agaacgucca acaagacaac     1620

agcgaagcag gaacccagcc ccaaguccaa accgacgcac aacagaccag ccagagccca     1680

cccucccccg agcucacauc agaagaaaau aagaucccag acgcagacaa ggccaacgaa     1740

aagaaagucg accagccccc ggaggccaag aaacccaaaa ucaaaguggu caacguagaa     1800

cuccccaucg aagcaaaccu ggucuggcag cuagguaaag acuuauuaaa cauguacauc     1860

gaaaccgaag gcaaaaugau aaugcaagau aaacucgaaa aagaacgcaa cgacgccaaa     1920

aacgcagucg aagaauacgu auacgaguuc cgggacaaau uaugcggccc auacgaaaaa     1980

uucaucugug aacaagacca ccaaaacuuu cuacguuuau uaaccgaaac cgaagacugg     2040

cucuacgaag aaggcgaaga ucaagcaaaa caggcuuacg ucgauaaacu cgaagaacua     2100

augaaaaucg gaacgccggu caaagugcgg uuccaagaag cagaagaacg ucccaaaaug     2160

uucgaggaac ucggacaaag acuccaacac uacgcgaaaa ucgccgccga cuuccgcaac     2220

aaagacgaga aguacaacca caucgacgaa ucagaaauga agaaaguaga aaagucgguc     2280

aacgaaguaa uggaauggau gaacaacgua augaacgccc aagccaaaaa gucccucgac     2340

caagacccag ucguccgagc acaagaaauc aaaaccaaaa uuaaggaacu caacaauacc     2400

ugcgagcccg ucguaacgca accgaaacca aaaauagaau cccccaaacu cgaacgaacc     2460

cccaacgggc cgaacaucga caagaaagaa gaagaccucg aggacaaaaa caacuucgga     2520

gcagaaccac cacaccaaaa cggcgaaugc uacccaaacg agaaaaacag cgucaacaug     2580

gaccucgauu gaggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  5645
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt10)

<400>  5645
gggagaaagc uuaccauggc cgauaagguc cgccgccaac gcccccgccg cagggugugc       60

ugggcgcucg ucgccgucuu gcucgccgau uuacucgccu uaucggacac cuuagccguc      120

augagcgucg auuuaggguc ggaaaguaug aaagucgcga ucgugaagcc gggggucccg      180

auggagaucg ugcucaacaa agagagcaga cgcaagaccc ccgucauagu cacguuaaag      240

gagaacgagc gcuuuuucgg ggauucggcc gccucgaugg ccaucaaaaa cccgaaagcc      300

accuugaggu auuuucaaca uuuguuaggc aaacaagccg acaauccgca cgucgccuug      360

uaucaagcga gguuucccga acaugaauua accuuugauc cgcaacgcca aaccguccau      420

uuccaaauau cgagccaauu acaauuuagc ccggaagagg uccucgggau ggucuugaac      480

uacagcagga gcuuggccga ggacuucgcc gaacaaccga uaaaagacgc cgucauaacg      540

gucccggugu uuuuuaauca agcggaaagg agggccgucu uacaagccgc caggauggcc      600

ggguugaagg ucuuacaauu gauaaacgau aauacggcga ccgcguuguc guacggggug      660

uuuaggagaa aggacaucaa uacgaccgcg caaaacauaa uguuuuacga uauggggagc      720

gggucgacgg ucuguacgau cgucacguau caaaugguca aaaccaaaga ggccggcaug      780

caaccgcaau uacaaauaag aggggucggg uucgauagga cguuaggcgg guuagaaaug      840

gaauugagau ugagggagag guuagccggc uuguuuaacg aacaaaggaa agggcaacgc      900

gccaaagacg ucagagaaaa ucccagggcg auggcgaaau uauuaaggga agccaacaga      960

uugaagacgg uguugucggc gaaugccgau cauauggccc aaaucgaggg guuaauggac     1020

gacgucgauu uuaaagccaa ggucaccagg gucgaguucg aagaacucug cgccgaucuc     1080

uucgaaagag ucccgggccc gguccaacaa gcguugcaau cggcggagau gucguuagac     1140

gaaaucgaac aagucauauu agucgggggc gcgaccagag ugccgcgcgu ccaagaaguc     1200

uuauuaaaag cggucgggaa agaagaauua ggcaaaaaua uaaacgccga cgaggccgcg     1260

gcgaugggcg ccgucuauca agccgccgcc uugucgaagg cguucaaggu caaaccguuc     1320

guggugaggg acgccgucgu guauccgaua uuagucgaau uuacccgcga agucgaagaa     1380

gaaccgggca uccauucguu aaaacauaac aagagagucu uguuuagcag aaugggcccg     1440

uauccgcaga ggaaggugau aacguucaau agguauucgc acgacuuuaa uuuucauaua     1500

aauuaugggg auuuaggguu uuuaggcccg gaggacuuga gagucuucgg gagucaaaac     1560

uuaacgaccg ucaaauugaa gggcgucggg gauucguuua aaaaauaccc ggauuaugaa     1620

aguaaaggga uaaaagccca uuuuaauuua gacgaaucgg gggucuuguc guuggaucgc     1680

gucgaaagcg ucuucgaaac cuuagucgaa gauucggccg aggaagagag caccuugacg     1740

aaguugggga auacgaucag uucguuauuc ggggggggga cgaccccgga cgcgaaagaa     1800

aacgggaccg acaccgugca agaagaggaa gaaucgccgg ccgaaggcuc gaaagaugaa     1860

ccgggcgaac aagucgaauu gaaagaagag gccgaagcgc cggucgaaga cgggagccaa     1920

ccgccgccgc cggagccgaa aggggacgcc acgccggaag gggagaaagc gaccgagaag     1980

gagaacggcg auaaaagcga agcgcaaaag ccgucggaaa aagccgaagc cggcccggaa     2040

gggguggccc cggcgccgga aggggaaaaa aaacaaaaac cggcgcgcaa aagaaggaug     2100

gucgaagaaa uaggcgucga auuagucguc uuagauuuac cggaucuccc ggaagacaaa     2160

uuagcccaaa gcguccaaaa guugcaagau cucaccuuga gggauuuaga aaaacaagag     2220

agagagaagg ccgcaaauuc gcucgaggcc uuuaucuucg aaacgcaaga uaaauuauau     2280

caaccggaau aucaagaggu caguaccgaa gaacaaaggg aagaaauaag cggcaaauug     2340

ucggcggcca guacgugguu agaagacgaa ggggucgggg cgacgaccgu caugcucaaa     2400

gaaaaauuag ccgaauuacg caaauuaugu cagggcuuau ucuucagagu cgaagaaagg     2460

aaaaaauggc cggagagauu aagcgcguug gacaacuugu ugaaucacag uucgauguuu     2520

uugaaaggcg cgagauugau accggaaaug gaucaaauau uuaccgaagu cgaaaugacc     2580

acccucgaaa aggugauaaa cgaaacgugg gcguggaaaa acgccaccuu agcggaacaa     2640

gccaaauuac cggcgaccga aaaaccgguc cucuugagca aggauaucga ggccaaaaug     2700

auggcguuag auagggaagu ccaauacuua uugaacaaag cgaaauucac gaaaccgaga     2760

ccgagaccga aagauaaaaa cggcacgaga gccgaaccgc cguugaacgc gucggcgucg     2820

gaucaaggcg aaaaagugau accgccggcc gggcaaaccg aggacgccga accgaucagc     2880

gagccggaaa aggucgaaac cgggagugaa ccgggggaua ccgaaccgcu cgaacucggg     2940

gggccggggg ccgagccgga gcaaaaggag cagagcaccg ggcaaaaaag accgcucaaa     3000

aaugaugagu ugugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  5646
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt10)

<400>  5646
gggagaaagc uuaccaugcc ggaggagacg caaacgcagg aucagccgau ggaggaagag       60

gagguagaga cauucgcauu ccaggcggag auagcacaau uaaugucguu aauaauuaac      120

acguucuaca guaacaagga gauauucuua agggaguuaa uaucgaacuc gucggacgcg      180

uuggacaaaa uacgauacga aucguuaacg gacccgucga aguuagacuc ggguaaggag      240

uugcacauca acuuaauucc gaacaagcag gaccggacgu uaacgauagu agacacgggu      300

auaggaauga cgaaagcgga cuugauaaac aacuuaggaa cgauagcgaa gucggguacu      360

aaggcguuca uggaggcauu acaggcgggu gcggacauaa guaugauagg ucaauucggg      420

gucggauucu acucggcaua cuuagucgca gagaagguaa cgguaaucac gaagcacaac      480

gacgacgaac aauacgccug ggagaguucg gcggguggua guuucacggu acgcacugac      540

acgggugagc cgauggguag ggguacgaag guaauauuac acuuaaagga ggaccagacg      600

gaauacuuag aggagcgccg gaucaaggag auuguuaaaa agcacucgca auucaucggc      660

uacccuauaa cguuauucgu cgagaaggag cgcgacaagg agguuaguga cgacgaggcg      720

gaggagaaag aggacaagga ggaggagaag gaaaaggagg agaaggaguc ggaggacaag      780

ccggagauag aggacguagg aucggacgag gaggaggaga agaaggacgg ggacaaaaag      840

aagaagaaaa agauaaagga gaaauacaua gaccaagagg aguuaaacaa gacgaagccg      900

aucuggacaa ggaacccgga cgacauaacg aacgaggagu acggugaguu cuacaagucg      960

uuaacaaacg acugggagga ccacuuagcg gucaaacacu ucaguguaga ggggcaguua     1020

gaguuccgcg cguuguuauu cguaccgagg cgcgcgccgu ucgacuuauu cgagaaccgg     1080

aagaagaaaa acaauauaaa guuauacguc cgaaggguau ucauaaugga caacugcgag     1140

gaguuaauuc cggaguaccu caacuucaua cgcggugucg ucgacucgga agacuugccg     1200

uuaaacaucu cgcgagagau guuacagcag ucgaagaucu uaaagguaau acgcaagaac     1260

uuagucaaga agugcuuaga guuauucacg gaguuggcag aggacaagga gaauuacaaa     1320

aaauucuacg agcaguucuc gaagaauaua aaguuaggga uacacgagga cagucagaac     1380

cgaaaaaagu uaucagaauu auuacgauac uauacgagug cgucggggga cgaaaugguc     1440

aguuugaagg acuauuguac acggaugaag gaaaaccaaa agcacauaua cuacauaacg     1500

ggggagacga aggaccaagu ugcgaacucg gcauucgucg agcgcuuacg gaagcacggg     1560

uuagagguca uauacaugau cgaaccuaua gacgaguauu gcguacagca auugaaggag     1620

uucgagggga agacauuagu aaguguaaca aaggaggggu uagaguugcc ggaggacgag     1680

gaggagaaga agaagcagga ggagaagaag acgaaguucg agaacuuaug caagauaaug     1740

aaggacauau uagagaagaa ggucgagaag gucgucgucu cuaacagguu gguaacgucg     1800

ccgugcugca uaguaacguc gacuuacggu uggacugcga acauggaacg aauaaugaag     1860

gcgcaggcgu uaagggacaa caguacgaug gguuacaugg cggcaaagaa gcauuuagaa     1920

aucaacccgg accacucgau cauagagacg uuacgacaga aggcggaggc ggacaagaac     1980

gacaagagug ucaaagacuu aguaauauua uuauacgaga cggcguuguu aucgaguggg     2040

uucucguuag aggacccaca aacucacgcg aaccgaauau aucgcaugau aaaguuggga     2100

uuaggaaucg acgaggacga cccgacggcg gacgacacau cggcggccgu aaccgaggag     2160

augccgccgu uagaggguga cgacgauacu ucgcggaugg aggagguaga cugaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  5647
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt10)

<400>  5647
gggagaaagc uuaccaugcc ggaggagguc caucauggcg aggaagaggu ggagacguuu       60

gcguuucaag cggaaaucgc gcaguugaug ucgcucauaa ucaauacguu uuauaguaau      120

aaggagauau uuuugcgcga acucaucagc aaugccucgg augcguuaga uaaaauccgc      180

uaugagucgu ugaccgaucc gagcaaguua gauagcggga aagaacucaa gaucgauaua      240

auaccgaauc cgcaggagag gaccuugacg uuggucgaua cggggaucgg gaugaccaag      300

gcggauuuga ucaauaacuu ggggaccauc gcgaaaucgg gcaccaaggc guuuauggaa      360

gcguugcagg ccggggcgga uaucucgaug auagggcagu uuggggucgg guuuuauucg      420

gccuauuugg uggcggagaa agucgucguc auaaccaagc auaaugauga ugagcaguau      480

gcgugggagu cgucggcggg gggcucguuu accgugcgcg ccgaucaugg ggagccgauc      540

gggaggggca ccaaggucau auugcauuug aaagaggauc agacggagua ucucgaggaa      600

aggcgcguga aagagguggu gaagaagcau ucgcaauuua uaggguaucc gaucacguug      660

uauuuagaga aggaacgcga gaaagagauc ucggaugaug aagcggaaga ggagaagggg      720

gagaaggagg aggaggauaa ggaugaugag gagaaaccga aaauagagga ugucgggucg      780

gaugaggagg augauagcgg gaaagauaaa aagaagaaga ccaagaagau aaaggaaaag      840

uauauagauc aggaggaauu aaauaagacc aagccgauau ggacgcgcaa uccggacgau      900

auaacccagg aggaguaugg cgaguuuuau aagagcuuga ccaaugauug ggaagaucau      960

uuggccguca aacauuuuuc ggucgagggg caguuggagu uucgcgccuu guuguuuaua     1020

ccgcgccgcg ccccguuuga uuuauuugag aauaaaaaga agaagaauaa uaucaaauug     1080

uaugugagga ggguguuuau cauggauagc ugugaugagu uaauaccgga guauuugaau     1140

uuuauaagag gggucgucga uagugaggau uugccguuga auauaucgag ggagauguug     1200

cagcaaucga aaaucuuaaa ggucauacgc aagaauauag ucaagaaaug uuuggaguug     1260

uuuucggagc ucgccgaaga caaggagaau uauaaaaagu uuuaugaggc guuuucgaaa     1320

aauuugaagu uagggaucca ugaggauucg acgaacaggc gcagguuguc ggaguuguug     1380

cgcuaucaua ccucgcaauc gggggaugaa augaccucgu ugagugagua ugucucgaga     1440

augaaggaga cccagaaaag caucuauuau auaacggggg aaucgaaaga gcaggucgcc     1500

aauagcgccu uuguggagag ggucaggaaa aggggguuug agguggucua uaugaccgaa     1560

ccgauagaug aauauugcgu ccagcaauug aaggaguuug augggaaguc guuggugagc     1620

gucacgaagg agggguugga gcucccggag gaugaggagg aaaaaaagaa gauggaggag     1680

agcaaggcga aguuugaaaa ucucuguaaa uuaaugaagg aaauauugga uaagaaaguc     1740

gagaaaguga ccauaagcaa uagauuaguc ucgagcccgu guuguauagu gaccucgacc     1800

uaugggugga ccgccaauau ggagaggauc augaaggccc aggcguugcg cgauaauagc     1860

acgaugggcu auaugauggc gaaaaagcau uuggagauca auccggauca uccgaucguc     1920

gagaccuugc gccagaaagc ggaggccgau aagaaugaua aggcggucaa ggauuugguc     1980

guguuauugu uugagaccgc guuguugagc ucgggguuca gcuuagaaga uccgcagacg     2040

cauucgaauc gcauauauag gaugaucaaa uugggguuag ggaucgauga agaugagguc     2100

gcggccgagg aaccgaaugc cgccgugccg gaugagauac ccccguuaga gggcgaugaa     2160

gaugccagcc gcauggagga aguggauuga ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  5648
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt10)

<400>  5648
gggagaaagc uuaccaugcg cgcguugugg gucuuggguu uguguugugu cuuguugaca       60

uuugggagcg ugagggccga ugaugaagug gauguagaug ggaccgugga ggaagauuug      120

gggaagucga gggagggguc gagaaccgac gaugaagugg uacaaaggga agaggaagcc      180

auccaauugg acggguugaa ugcgucgcaa aucagggaau ugagagaaaa aucggagaaa      240

uucgcguuuc aggcggaggu gaaucgcaug augaaguuga uuauaaauag uuuguauaag      300

aacaaggaaa ucuuuuuaag agaguugaua aguaaugcgu cggacgcgcu cgacaaaauc      360

agguugauau cguuaaccga ugagaacgcg cucucgggca augaagaguu gacggucaag      420

aucaaaugug auaaagaaaa aaauuuauug cacgucaccg auacaggggu cgggaugacg      480

agggaggaau uggugaagaa uuuggggacg aucgcgaaau cggggaccuc ggaauuuuug      540

aauaagauga ccgaagcgca agaggauggg caaagcaccu cggaauugau cgggcaauuu      600

ggcgucggcu uuuauucggc cuuuuugguc gccgauaaag ucaucgugac cucgaagcau      660

aauaaugaca cgcaacauau uugggaaagc gauucgaaug aguucucggu cauagccgau      720

cccagaggga auaccuuggg gcgcgggacg acgauaaccu uggucuugaa agaggaagcc      780

agcgauuauu uggaguuaga uaccauaaag aauuugguca aaaaguacuc gcaauuuauu      840

aauuuuccca ucuaugugug gucgagcaaa accgagaccg ucgaagaacc uauggaagaa      900

gaagaagccg cgaaggagga aaaggaggag agcgacgaug aggccgccgu ggaagaggag      960

gaagaggaaa agaaaccgaa aacgaaaaag gucgaaaaga cggucuggga uugggaguug     1020

augaacgaua uuaagccgau cuggcaaagg cccucgaagg agguggaaga ggaugaauau     1080

aaggcguuuu auaaaucguu uucgaaagag ucggacgauc cuauggcgua cauccauuuc     1140

accgcggagg gggaagucac cuuuaagucg auauuguuug ugccuaccuc ggcgccgcgc     1200

ggguuguucg augaguaugg cucgaaaaaa ucggauuaua uaaaguugua uguaaggaga     1260

gucuuuauua cggaugauuu ucaugauaug augccgaaau auuuaaauuu cgugaaaggg     1320

gucgucgaca gcgacgauuu accguugaac gucucgcgcg aaaccuugca acaacauaag     1380

uuauugaaag ucaucaggaa aaaauuggug cgcaagaccu uggauaugau aaaaaaaauc     1440

gccgacgaca aauauaacga uaccuuuugg aaggaauuug ggacaaauau uaaguugggg     1500

gucauagagg aucauucgaa caggacccgc uuggccaagu uguugcgcuu ucaaucgucg     1560

caccauccga ccgauaucac cucguuagau caauacgucg agaggaugaa agagaagcaa     1620

gauaagauau auuuuauggc cgggaguucg aggaaggaag ccgagucguc gccguucguc     1680

gaaagguugu ugaaaaaagg guacgaggug auauaucuca cggagccggu cgaugaguau     1740

uguauacaag cguugccgga auuugauggg aaacgcuuuc aaaacguggc caaagagggg     1800

gucaaauuug augagucgga aaaaaccaaa gaaagccgcg aggccgugga aaaggaauuu     1860

gaaccguuau ugaauuggau gaaggauaag gcauugaaag auaaaaucga gaaagccguc     1920

gucagccaaa gauuaacgga aucgccgugc gcguuggugg caucgcaaua uggguggucg     1980

gguaauaugg aacgcauaau gaaagcccaa gcguaucaaa ccgggaaaga uauaucgacg     2040

aauuauuaug cgucgcaaaa aaaaaccuuu gagauaaauc cgcgccaucc cuugauucgc     2100

gauauguuga ggcgcauaaa agaggaugaa gacgauaaaa cggucuugga uuuggcagua     2160

gucuuguuug agaccgcgac cuugcgcucg ggguauuuau ugccggauac caaggcguau     2220

ggggauagga uagagaggau guugcgcuug ucguugaaua ucgauccgga cgccaaaguc     2280

gaggaagaac cggaagaaga accggaggaa accgccgaag auacgacgga agauaccgaa     2340

caagaugaag acgaagaaau ggacguaggg accgaugagg aagaggagac ggccaaagag     2400

agcacggccg agaaagauga guugugagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  5649
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt10)

<400>  5649
gggagaaagc uuaccauggc gagggagcuc agggcguugu uguugugggg gaggagguug       60

aggccguugu ugagggcgcc ggccuuggcg gccgugccgg gggggaagcc gaucuugugu      120

ccgaggcgca ccaccgccca guuggggccg aggaggaauc cggcguggag cuugcaagcg      180

gggagguugu uuaguaccca gacggcggag gauaaggagg agccguugca uucgaucaua      240

ucgucgacgg aaagugucca ggggucgacg aguaagcaug aauuucaagc ggagacgaaa      300

aaguuguugg auauagucgc gaggucguug uauagugaga aggagguguu uauaagggag      360

uugauaagca augccaguga ugccuuggag aaguugaggc auaaguuggu cagcgauggg      420

caggccuugc cggagaugga gauccacuug cagacgaaug ccgagaaggg gacgaucacc      480

auccaggaua ccgggaucgg gaugacccaa gaagaguugg ugagcaauuu ggggaccauc      540

gcgaggucgg ggucgaaggc guuuuuggau gcguugcaga aucaggcgga ggcgaguagu      600

aagauaauag ggcaauuugg ggucggguuu uacagugcgu uuauggucgc cgauagggug      660

gaggucuaca gcaggagcgc cgcgccgggg aguuuggggu aucagugguu gagugauggg      720

ucgggggucu uugagaucgc cgaggcgagc ggggugagga ccgggacgaa gauaauaauc      780

cauuugaagu cggauuguaa ggaguucucg agcgaggcga gggugaggga uguggugacg      840

aaguacagca acuuugugag cuucccguug uacuugaaug ggcgcaggau gaauaccuug      900

caggcgauau ggaugaugga uccgaaggau gugagggagu ggcaacacga ggaauuuuau      960

agguaugucg cccaggccca ugauaagccg agguauacgu ugcauuauaa gaccgaugcg     1020

ccguugaaua uaaggaguau auuuuauguc cccgauauga agccgucgau guuugauguc     1080

aguagggagu uggggagcag cgucgccuug uauagccgca agguguugau ccagaccaag     1140

gcgacggaua uauugccgaa gugguugagg uuuauacgcg ggguggugga uucggaggau     1200

auaccguuga auuugagcag ggaguuguug caggagagug cgcucauaag gaaguugagg     1260

gaugucuugc agcaaagguu gaucaaguuu uuuauagacc agaguaaaaa ggacgccgag     1320

aaguaugcga aguuuuuuga ggauuauggg uuguuuauga gagaggggau agucaccgcc     1380

acggaacagg aagugaagga agauaucgcc aaguuguugc gcuaugaaag uucggcguug     1440

ccgagcgggc aguugaccuc guugucggag uaugcgagca ggaugcgcgc cgggacgagg     1500

aauauauauu auuugugugc gccgaauagg cauuuggccg agcauagccc guauuaugaa     1560

gcgaugaaga aaaaggauac ggagguguua uuuuguuucg agcaguuuga ugaguuaacg     1620

uuguugcauu ugcgcgaauu ugauaagaaa aaguugauau cgguggaaac cgauauagug     1680

gucgaucauu auaaggagga gaaguuugaa gauaggucgc cggcggccga guguuugagc     1740

gagaaggaga cggaggaguu gauggcgugg augagaaaug uguuggggag ucgcgucacg     1800

aaugucaagg ugaccuugcg cuuggauacg cauccggcga uggugacggu cuuggagaug     1860

ggggccgcga ggcauuuuuu gaggaugcag caguuggcca agacccaaga agagagggcg     1920

caguuguugc agccgacguu ggagaucaau ccgaggcaug cguugaucaa aaaguugaac     1980

caguuacgcg cgagugaacc gggguuggcg caguuguugg uggaucaaau auaugagaau     2040

gcgaugauag ccgccggguu ggucgaugau ccgagggcga uggucgggag guugaacgag     2100

uuguugguga aggccuugga aaggcacuga ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  5650
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt10)

<400>  5650
gggagaaagc uuaccauggg uaagaucucg ucauuaccga cgcaguuguu caagugcugc       60

uucugcgacu ucuuaaaggu aaagaugcac acgaugucga guucccacuu auucuacuug      120

gccuuaugcu uguugacguu caccuccucg gcgaccgcag ggccggagac cuugugcggc      180

gcggaguuag uagacgcguu acaguucguc ugcggugacc gagguuucua cuucaacaag      240

ccgacggguu acggguccuc gucgcgccgu gcaccgcaga cgggcaucgu ugacgaaugc      300

ugcuuccguu cuugcgaccu ccgucgcuua gagauguacu gcgcgccguu gaagccggcg      360

aagucggccc guucgguacg cgcgcagcgg cacacggaca ugccaaagac gcagaaagag      420

guccacuuaa agaacgcguc gcguggaucg gccggcaaca agaacuaccg gaugugagga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  5651
<211>  760
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt10)

<400>  5651
gggagaaagc uuaccauggg cauacccaug gguaagucaa uguugguguu auuaaccuuc       60

uuagccuucg ccucgugcug caucgcggcc uaccguccgu cagagacccu augcggcggg      120

gagcuaguag acacgcuaca guucgugugc ggcgaccggg gguucuacuu cucgcgcccc      180

gcgucgcgcg ugucccgccg uucgcgcggc aucguagagg agugcugcuu ccgaucaugc      240

gacuuggccu uauuagagac cuacugcgcc accccggcca agucggagcg agacgugucg      300

acgccgccga ccguguuacc ggacaacuuc ccccgguacc ccgucggcaa guucuuccag      360

uacgacacgu ggaagcaguc gacucagaga cuucgucgcg gguuaccggc guuguugcgu      420

gcccgacgag gccacgugcu agccaaggag uuagaggcgu uccgcgaggc gaagcggcac      480

cgcccguuaa ucgcguuacc cacucaggac cccgcgcacg gaggcgcccc gcccgagaug      540

gcgucgaacc gaaagugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      600

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      720

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            760


<210>  5652
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt10)

<400>  5652
gggagaaagc uuaccaugaa cucguucagu acgucggcgu ucggccccgu cgcguucucg       60

uuagguuugu uauuggucuu accggcggcg uucccagcgc ccguuccacc gggugaggac      120

ucgaaggacg uugcggcgcc ccaccgacag cccuugaccu cguccgagcg uaucgacaag      180

cagauccgau acaucuuaga cgguauaagu gcguuacgca aggagacgug caacaaaucg      240

aacaugugcg agaguucgaa ggaggcguua gccgagaaca accucaacuu gccgaagaug      300

gcggagaagg acgggugcuu ccagaguggg uucaacgagg agacaugcuu aguaaagauc      360

auaacgggcc uccuugaguu cgaggucuac cucgaguacu uacagaacag guucgaguca      420

ucggaggagc aggcacgcgc gguucaaaug ucgacgaagg uauugaucca guuccuccag      480

aagaaggcca agaacuuaga cgcgaucacg acgccggacc cgacuaccaa cgcgaguuug      540

uuaacuaagu uacaggcgca gaaccagugg uugcaggaca ugaccaccca cuugaucuug      600

cggucguuca aggaguucuu gcagaguucu uuaagagcgu uaaggcagau gugaggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  5653
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt10)

<400>  5653
gggagaaagc uuaccaugcc guuauugugg uuaagggggu ucuuguuagc gucgugcugg       60

aucaucgugc guucgucgcc gacgcccggg ucggaggguc acucggccgc accggacugc      120

ccaaguugcg cacuugccgc guuaccgaag gacguuccga acucgcagcc ggagaugguu      180

gaggccguga aaaagcacau auugaacaug uuacaccuaa agaagcgacc ggacguaacg      240

cagccggucc ccaaagcggc ccuauuaaac gcuauacgga aguuacacgu ugggaaggua      300

ggcgagaacg guuacgugga gaucgaggac gacaucgggc gccgcgccga gaugaacgag      360

uuaauggagc agacgucaga gaucaucacc uucgcggagu cgggcacugc gcguaagacu      420

uugcacuucg agaucucgaa ggaggguucg gacuuaucgg ugguagagcg ggccgaggug      480

ugguuauucu ugaaggugcc gaaggcgaac cgaacgcgaa ccaaggucac cauccgauug      540

uuccagcaac agaaacaccc ccaggggagu uuagacaccg gggaggaggc cgaggaggua      600

ggucucaagg gggagcgauc cgagcuccuc uuaucggaga agguggucga cgcgcgaaag      660

ucuacguggc acguauuccc ggugucgucg ucgauccagc gccuacuuga ccagggcaag      720

aguucguugg acguccgcau agcgugcgag cagugccagg agucgggcgc gucucuugua      780

uuguuaggga agaagaagaa gaaggaggag gagggugagg ggaagaagaa ggggggcggg      840

gagggcgggg cgggcgcgga cgaggagaag gagcagucuc accggccguu cuuaauguua      900

caagcgcguc aaucggagga ccacccgcac cgacgacgcc gacguggguu agagugcgac      960

ggcaagguga acaucugcug caagaagcag uucuucguuu cauucaagga caucgguugg     1020

aacgacugga uaauagcccc gucgggguac cacgcgaacu acugcgaggg cgagugcccg     1080

ucccacaucg ccgguacuuc gggcucgucg uuaucguucc acaguacggu uauaaaccau     1140

uaccguaugc guggacacuc ccccuucgcg aacuugaaga guugcugcgu gccgaccaag     1200

uugcguccca ugucgaugcu uuacuacgac gacggccaga acauuauaaa gaaggacauc     1260

cagaacauga ucgucgagga augcggcugc aguugaggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  5654
<211>  1441
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt10)

<400>  5654
gggagaaagc uuaccaugga cgguuuaccg ggacgagcuu ugggugcggc uuguuuguua       60

uuguuggcag cggguugguu aggcccggaa gcguggggau cgccgacacc ucccccuacu      120

ccggcggcgc caccgccccc gccaccgccg gggucgccag gcggguccca agauacuugc      180

acaaguugcg gggguuuccg acgacccgag gaauugggac gcguagacgg ugauuucuug      240

gaagcuguaa agcgucauau cuuaucgcgu uuacagaugc gagggcgacc gaacauaacc      300

cacgccguac cgaaggcggc gaugguuacc gcguuacgaa aguuacaugc ugggaagguu      360

cgugaggacg ggcguguaga gaucccccau uuggacgggc acgccucgcc aggggccgac      420

gggcaagagc gagucucgga gauaauuagu uucgcggaga cugacggguu agcgucgucg      480

aggguacguu uauacuucuu cauaucgaac gaggguaacc aaaacuuguu cguaguacag      540

gcgaguuuau gguuauaccu uaagcuauua ccauacguuu uagagaaggg gucgcgucga      600

aaaguaaggg uaaagguaua cuuccaagag caaggucacg gcgaccgaug gaacauggua      660

gagaagcggg uugaccuuaa gcgaagugga uggcacacgu ucccguuaac ugaggcaaua      720

caggcauuau ucgagcgugg agagcgccgc uuaaacuuag acguacaaug cgacucgugc      780

caggaguugg cagucguccc aguauucgua gaccccgggg aggagaguca ucgaccguuc      840

guaguaguac aggcgcgcuu aggugacucg cgacaccgaa uccggaagcg ugguuuagag      900

ugcgacggua ggacgaacuu gugcugccga cagcaguuuu uuauagacuu uagguugauc      960

ggguggaacg acuggauaau ugcgccgaca ggauacuacg guaacuauug cgaaggaagu     1020

ugcccggcgu acuuagcggg ggugccaggu ucggcaucgu cguuccacac ugcgguaguu     1080

aaccaguacc gaaugcgagg auugaauccg gggacaguaa acucgugcug caucccgacg     1140

aaguuaagua cgaugucgau guuauacuuc gacgacgagu acaacauagu aaagcgcgac     1200

gucccgaaca ugaucguaga agagugcggu ugcgcgugag gacuaguuau aagacugacu     1260

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1380

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1440

u                                                                     1441


<210>  5655
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt10)

<400>  5655
gggagaaagc uuaccauggc guugaggguc cucuuauuga ccgccuugac cuuaugccau       60

ggguuuaauu uggauacgga gaacgccaug acguuucagg agaaugccag gggguuuggg      120

cagagcgucg ugcaguugca ggggagcagg gucguggugg gggcgccgca ggaaaucgug      180

gccgccaauc agagggggag cuuguaucag ugugauuaua gcacgggcag cugugagccg      240

auacgcuuac aggugccggu ggaggccgug aauaugucgu uaggguuguc guuggcggcg      300

accacgagcc cgccgcaguu gcucgccugu gggccgacgg ugcaccaaac guguagcgag      360

aauacguaug ucaagggguu guguuucuug uucggcagua auuugaggca acaaccgcag      420

aaguuuccgg aggcguugag ggggugcccc caggaggauu cggauaucgc guucuugauc      480

gaugggagug ggaguaucau cccgcaugau uuuaggagaa ugaaagaguu cgugagcacc      540

gucauggagc aguugaaaaa gaguaagacc uuguuuaguu uaaugcagua uucggaagaa      600

uuucgcauac auuuuacguu uaaggaauuu caaaauaauc cgaauccgag gagcuuaguc      660

aagccgauca cccaguuguu ggggcgcacc cauaccgcga ccgggauacg caaagugguc      720

agggaguugu uuaauaucac caacggggcc aggaagaaug cguuuaagau auuggucgug      780

aucacggaug gggagaaguu uggcgauccg cucggguaug aggaugucau accggaggcc      840

gaucgcgaag gggucauaag guaugugaua ggggucggcg augcguuuag gucggagaag      900

aguaggcaag aguugaauac caucgcgagu aagcccccga gggaucaugu guuucaggug      960

aauaauuuug aggcguugaa gacgauacag aaucaguuga gggaaaagau cuuugcgauc     1020

gaggggacgc agacgggguc gaguucgagu uuugagcacg agaugaguca ggagggguuu     1080

ucggcggcca uaacgaguaa ugggccguug uugagcacgg uggggagcua ugauugggcc     1140

gggggggugu uuuuguauac gaguaaagag aagaguaccu uuauaaauau gacgcgcgug     1200

gacagcgaua ugaaugaugc cuacuugggg uaugcggccg ccauaaucuu gaggaaucgc     1260

guccagagcu ugguccucgg ggcgccgagg uaucagcaua uaggguuggu cgccauguuu     1320

aggcagaaua cgggcaugug ggagucgaau gccaauguga aagggacgca gauaggggcc     1380

uauuuugggg ccagcuugug uagcgucgau guggauagca augggucgac cgacuugguc     1440

uugauagggg ccccgcauua uuacgaacaa accagggggg ggcaggucag cgugugcccg     1500

uugccgaggg ggagggcgag guggcagugu gaugccgucu uguacgggga gcaggggcag     1560

ccgugggggc gcuuuggggc ggccuugacg guguuggggg augugaaugg ggauaaguug     1620

acggaugucg ccauaggggc cccgggggaa gaggauaaua ggggggccgu cuauuuguuu     1680

caugggacga gugggucggg gauaagcccg agucauagcc agaggaucgc ggggagcaag     1740

uuaaguccgc gcuuacagua uuuuggccag ucguugagug gggggcagga uuugaccaug     1800

gauggguugg ucgacuuaac cgucggggcc cagggccacg ucuuguuguu gaggagucag     1860

ccggucuuga gggugaaagc cauaauggaa uuuaacccga gagagguggc caggaaugug     1920

uuugagugua augaucaggu cgugaaaggg aaggaggcgg gggaggugcg cgucugcuua     1980

cauguccaga aaucgaccag ggacagguua agggaggggc agauacaaag ugucgugacg     2040

uaugauuugg cguuggauag ugggcgcccg cauucgaggg cgguguuuaa ugagacgaag     2100

aacagcacga ggagacagac gcaagucuug ggguugacgc agaccuguga aaccuugaag     2160

uugcaguuac cgaauugcau agaggauccg gugagcccga uagucuugag guugaacuuc     2220

aguuuggugg ggaccccguu gagcgccuuu gggaauuuga ggccgguguu ggcggaggau     2280

gcgcagaggu uguuuacggc guuguuuccg uuugagaaaa auugugggaa ugauaauauc     2340

ugccaggaug auuugucgau aacguuuagc uuuaugagcu uggauuguuu ggucgucggg     2400

gggccgaggg aguucaaugu gaccgugacg guccgcaaug auggggaaga caguuaucgc     2460

acccagguca ccuuuuuuuu ucccuuggau uugagcuaua ggaaggugag cacguugcag     2520

aaucagagga gccagaggag cuggcgcuug gccugcgaga gcgcgagcag caccgagguc     2580

ucgggggcgu uaaagagcac gaguugcagu aucaaucauc cgauauuucc ggaaaauucg     2640

gaggugaccu uuaauaucac cuuugauguc gauagcaagg ccagcuuggg gaauaaguug     2700

cucuuaaagg cgaaugugac gucggagaau aauaugccgc gcaccaauaa gaccgaauuu     2760

caguuggagu ugccggugaa auacgcgguc uauauggugg ugacgucgca uggggucagu     2820

accaaguauu ugaauuucac ggcgucggag aauaccaguc gcgucaugca gcaucaguau     2880

caagucagua auuuggggca gaggucguug ccgauaaguu uggucuuuuu ggucccggug     2940

cgcuugaauc aaaccgucau cugggauagg ccgcagguca ccuuuagcga gaauuugagu     3000

aguaccugcc auaccaagga gagguugccg ucgcacagug auuucuuggc cgaauugagg     3060

aaggcgccgg ucgucaauug uagcauagcc gucugucaaa ggauccaaug ugauaucccg     3120

uuuuucggca uccaagagga auuuaaugcc accuugaagg ggaauuuguc guuugauugg     3180

uacauaaaaa cgagccacaa ucauuuguug aucgucagua ccgcggagau auuguuuaau     3240

gauucggugu uuacccucuu accggggcag ggggccuuug ucaggagcca aaccgagacc     3300

aaggucgagc cguuugaggu gcccaauccc uugcccuuga uaguggggag uagugucggg     3360

ggcuuguugu uguuggcguu gauaaccgcc gccuuauaca aauugggguu uuuuaaaagg     3420

caguauaagg acaugaugag ugaggggggg cccccgggcg cggagccgca augaggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  5656
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt10)

<400>  5656
gggagaaagc uuaccauguu uaguuuaaaa accuugccgu ucuuauugcu cuugcacguc       60

caaaucagua aagcguuccc ggucagcagc aaggaaaaga acaccaagac cguccaagau      120

uauuuagaga aauuuuauca gcucccgucg aaucaauacc aaagcacccg caaaaacggg      180

accaacguca uagucgagaa auugaaggag augcaaaggu ucuucggccu caacgucacc      240

ggcaaaccga acgaagagac cuuagauaug augaagaaac cgaggugcgg ggucccggau      300

ucgggggggu ucaugcucac gccggggaau ccgaaauggg agaggaccaa ucucacguau      360

cgcaucagga auuacacgcc gcaauuaagc gaagccgaag ucgagcgcgc cauaaaagac      420

gcguucgagu uguggucggu cgccagcccg uugauauuua cgcgcauaag ccaaggggaa      480

gccgacauaa auaucgccuu cuaucagcgc gaccaugggg auaacagccc guucgacggg      540

ccgaacggga uauuggccca cgcguuccaa ccggggcagg ggaucggggg ggacgcccac      600

uucgacgcgg aggagaccug gacgaauacg agugccaacu auaaucucuu cuuggucgcc      660

gcccacgagu ucgggcacag ccucggcuug gcccauagua gcgauccggg ggcgcucaug      720

uacccgaauu acgccuuucg cgagacgucg aauuauagcu ugccgcagga cgauauagac      780

gggauccaag cgauauacgg guugagcucg aauccgauac agccgaccgg gccgucgacc      840

ccgaagccgu gcgauccguc gcucaccuuc gacgccauaa cgaccuugag gggggagauc      900

uuguuuuuca aggaucgcua uuuuuggcgc cgccacccgc aauugcagcg cguggagaug      960

aacuucauca gcuuguuuug gccgaguuug ccgaccggga uccaagccgc cuacgaggac     1020

uucgaucgcg auuugaucuu uuuguucaag gggaaucagu auugggccuu aucgggguac     1080

gacaucuuac agggguaccc gaaagacauc agcaauuacg gguuuccguc gucggugcag     1140

gccaucgaug ccgccgucuu uuaucgcucg aagaccuauu uuuucgucaa cgaucaguuu     1200

uggcgcuacg acaaucagcg ccaguuuaug gaaccggggu acccgaaguc gaucagcggg     1260

gcguucccgg ggaucgaauc gaaggucgac gccgucuuuc aacaggagca cuuuuuucac     1320

guguuuucgg ggccgcgcua cuaugccuuc gacuugaucg cccaacgcgu cacgcgcguc     1380

gcccgcggga acaagugguu gaauugccgc uacgggugag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  5657
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt10)

<400>  5657
gggagaaagc uuaccauguc guuauggcaa ccuuugguau ugguauuauu ggucuuaggg       60

ugcugcuucg cagcgccgcg ucagcgacag ucgacauuag ucuuguuccc gggugacuua      120

cgaaccaacu uaacugaucg gcaauuagcu gaagaguauu uauacaggua cggcuacacg      180

cgcguagcgg agaugagggg ggagucuaag aguuuaggcc cagcauuacu cuuguugcag      240

aaacaguuau cguuacccga aacgggggaa uuagacucgg cgacacucaa ggcgaugcgc      300

acuccucguu gcggaguacc cgacuuggga cgauuucaga cauucgaggg ugauuugaag      360

uggcaccacc acaacauaac guacuggauc cagaacuacu cugaggacuu accucgugca      420

guaauagacg acgcuuucgc acgagcguuc gcuuuauggu cggccguuac acccuugacg      480

uuuacgcgag ucuauucgcg cgacgccgac auaguaauac aguucggggu agccgagcac      540

ggugacggcu acccauucga cgguaaggac gguuuauuag cgcacgcguu cccgccgggg      600

ccggguaucc agggcgacgc gcacuucgac gacgacgaau uauggucuuu agggaaaggg      660

guaguuguac cuacgcguuu cgguaacgcg gacggugccg caugccauuu cccguucaua      720

uucgaggggc gaucauauag ugcgugcacu acggacggac ggucggacgg guuacccugg      780

uguucgacua cugcgaacua cgacacggac gaccgauucg guuucugccc gucggagcgu      840

uuauacacgc aagacgguaa cgcggacggc aagccuugcc aguucccuuu cauauuccag      900

ggacagucgu acucggcaug cacaaccgac gggcggucgg acggguaccg guggugcgcg      960

acuacggcga acuacgaucg cgacaaguua uucggguucu gcccaacacg ggcagacucu     1020

accguaaugg gagggaacag ugccggagag uugugcguau uccccuucac guucuuggga     1080

aaagaguacu caacaugcac uucggaaggc cggggugacg gucgauugug gugcgccacu     1140

acgaguaacu ucgacucgga caaaaagugg gguuucuguc cugaccaggg cuauucguua     1200

uucuuaguag cagcacacga guucgggcac gcauuaggau uggaccacag uaguguaccc     1260

gaagcauuga uguauccgau guaccgauuu acggaagguc cgccguuaca caaggacgac     1320

guaaacggua uccgacacuu auacggccca cggccggagc cggaaccgcg cccaccgacc     1380

acaacgacuc cacagcccac ugcaccgccc acaguauguc cuacgggucc uccgacagua     1440

cacccgucgg agcgaccgac ggcagguccc acuggaccgc cgagugcagg gccgacgggg     1500

ccgccgaccg cagguccguc gacggcgaca acggucccgu uaucgcccgu agacgacgcg     1560

ugcaacguua acauauucga cgcaauagca gagauaggua accaguuaua cuuauucaag     1620

gacggcaagu acuggcgcuu uucggagggg cgaggaaguc gaccccaggg gccguucuua     1680

aucgcggaca aguggccggc auuaccucga aaguuagauu caguauucga ggagcgauua     1740

aguaagaaau uauucuucuu cucggguagg caaguauggg uauauacggg ugccuccgua     1800

uuagggcccc ggaggcucga caaguugggg cucggugcug acgucgcgca gguaacgggu     1860

gcuuuacgcu cgggucgagg aaagauguua uuauucagug gucgccgauu auggcguuuc     1920

gacguaaagg cacagauggu cgacccucga ucggcgucgg aggucgaccg uauguucccg     1980

gguguaccgu uagacacaca cgacguauuc caguaccgcg aaaaggcuua cuucugccag     2040

gauagguucu acuggcgagu cucgucgagg ucggaauuaa aucaaguaga ccagguaggg     2100

uaugucacgu acgacaucuu acagugcccg gaggacugag gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  5658
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt10)

<400>  5658
gggagaaagc uuaccaugca cccgggcgug uuagccgcgu uuuuguuucu cucguggacc       60

cacugcagag cguuaccguu gccgucgggg ggggacgagg acgaccucag cgaagaggau      120

uugcaauucg ccgaaaggua uuuacgcagc uauuaucacc cgaccaacuu ggccgggaua      180

uuaaaagaaa acgccgccuc gaguaugacc gaacgcuuga gggagaugca aaguuuuuuu      240

gggcucgaag ucaccgggaa guuggaugac aauacgcucg acgugaugaa gaaaccgcgc      300

uguggcgucc cggacgucgg ggaguauaac gucuuuccga ggaccuugaa guggaguaag      360

augaaccuca cguaucgcau cgucaacuau acgccggaca ugacccacag cgagguggag      420

aaagccuuua agaaggcguu uaaggucugg agugacguca ccccguuaaa cuucacgcgc      480

uugcaugacg ggaucgccga uauaaugauu agcuucggga ucaaagaaca cggggauuuu      540

uauccguucg acggcccgag cggguuauua gcccacgccu ucccgccggg cccgaacuac      600

gggggggacg cgcacuucga cgacgacgag acguggaccu cgucgaguaa gggguauaau      660

cucuucuugg ucgccgccca cgaauuuggg cauagucucg gguuggauca uaguaaagau      720

ccgggggccu ugauguuccc gauauauacg uauacgggga agucgcauuu cauguugccg      780

gacgaugacg uccagggcau acaaaguuug uacgggccgg gggacgagga uccgaauccg      840

aagcacccga agaccccgga uaagugcgau ccgagucuca guuuggacgc gaucacgucg      900

uugagggggg agaccaugau auucaaggau cgcuuuuuuu ggagguuaca cccgcaacaa      960

gucgacgccg aauuauuccu caccaagagc uucuggccgg aguugccgaa uaggaucgac     1020

gccgccuacg aacauccgag ccacgauuug auauuuauau uucgcgggcg caaguucugg     1080

gccuugaacg gguacgauau cuuagagggg uacccgaaga agaucagcga guuaggguug     1140

ccgaaggagg ucaaaaaaau cucggccgcc guccauuucg aagacaccgg gaaaaccuug     1200

uuauuuagcg ggaaucaagu guggcgcuac gacgacacca aucacaucau ggacaaggau     1260

uacccccgcu ugaucgagga ggauuuuccg gggaucgggg acaaggucga cgccguguac     1320

gaaaagaacg gguacauaua cuucuuuaau gggccgaucc aauucgagua uucgauaugg     1380

ucgaauagga ucgucagggu gaugccggcc aacaguaucc ucuggugcug aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  5659
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt10)

<400>  5659
gggagaaagc uuaccaugga aaccccgaac accaccgaag auuacgacac cacaaccgag       60

uucgacuacg gcgacgccac ccccugccaa aaagucaacg aacgcgccuu cggcgcccaa      120

cuccucccac cccuuuacuc ccucgucuuc gucaucggcc ucgucggcaa uauccucgua      180

guccucgucc ucguccaaua caaacgacuc aaaaacauga ccuccaucua cuuacucaac      240

uuagccaucu ccgaccuccu cuuccucuuc acccuccccu ucuggauaga cuacaaacuc      300

aaagacgacu gggucuucgg cgacgccaug ugcaaaaucc ucucgggcuu cuacuacaca      360

ggacucuacu ccgaaaucuu cuucaucauc cucuuaacua ucgaccgcua ccuagccauc      420

guccacgccg ucuucgcacu acgcgcccgc accguaaccu ucggcgucau caccucaauc      480

aucaucuggg cccucgccau ccucgccucc augcccggcc ucuacuucuc aaaaacccaa      540

ugggaguuca cacaccacac augcucacuc cacuuccccc acgaauccuu acgcgaaugg      600

aaacucuucc aagcccucaa acucaaccua uucggccuag uccucccacu acucgucaug      660

aucaucugcu acacaggcau caucaaaaua cuccuccgcc gccccaacga aaagaaaucc      720

aaagcagucc gccucaucuu ugucauaaug auaaucuucu uccuauucug gacccccuac      780

aaccucacca uccucaucuc aguauuccaa gacuuccucu ucacccauga augcgaacaa      840

ucacgccacu uagaccucgc cguccaaguc accgagguca uugccuacac ccacugcugc      900

gucaacccag uaaucuacgc cuucgucggc gaacgcuucc gcaaauaccu ccgucaacua      960

uuccaccgac gcgucgccgu acaccucguc aaauggcucc ccuuccuauc ugucgaccga     1020

uuagaacgcg ucuccuccac aagcccaagc accggcgaac acgaacucuc cgccggcuuc     1080

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  5660
<211>  853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt10)

<400>  5660
gggagaaagc uuaccaugcg aacauuagca ugcuuguugu uauuagguug cggguacuua       60

gcgcacgugu uagcagagga ggcagagauc ccgcgugagg uuaucgagcg cuuggcacga      120

ucgcagaucc acaguauccg agacuuacag cgguuguugg agaucgacuc agucggcucg      180

gaggacucgu uagacacgag uuuacgagcg cacggggugc acgccacgaa gcacguaccg      240

gagaagcgcc cguugccgau acgucgcaag cgaucgaucg aggaggcggu gcccgcgguu      300

ugcaagacgc gaaccgucau cuacgagauc ccacgaucgc agguagaccc uaccucggcu      360

aacuucuuaa uauggccucc augcguagag gucaagcguu gcacggggug cugcaacaca      420

ucgucgguua agugccagcc gucgcgagug caccaccguu cgguaaaggu ggccaagguu      480

gaguacguac gaaagaagcc caagcuaaag gagguucagg uucgauugga ggagcacuua      540

gagugcgcuu gcgccacgac gaguuugaac cccgacuacc gugaggagga cacggggcga      600

ccgcgcgagu cgggcaagaa gcgaaagcga aagcgguuga agccgacgug aggacuaguu      660

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga      720

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag      840

agccaccaga auu                                                         853


<210>  5661
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt10)

<400>  5661
gggagaaagc uuaccaugaa ccguugcugg gcccuuuucu ugucguuaug cugcuacuug       60

cgcuuggugu cggccgaggg ugauccgaua ccggaggagc uguacgagau gcuaucugac      120

cacaguauaa ggucauucga cgacuugcag cgauuauuac acggggaccc gggugaagag      180

gacggggcgg aguuagacuu aaacaugacg cgcucgcacu cgggugggga guuggagucg      240

uuagcgcggg ggcggcgauc guuagggucg uugacgaucg cggagccugc gaugaucgcg      300

gagugcaaga cgcguacgga ggucuucgag auaucgcgac guuuaaucga ccgaaccaac      360

gcaaacuucu uaguauggcc cccuugcguc gagguacaga ggugcagugg augcugcaac      420

aaccgaaacg uccagugcag gccgacgcag guucaguugc guccgguaca aguccguaag      480

aucgagaucg uccguaagaa gccgauauuc aagaaggcua cgguaaccuu agaggaccau      540

cucgccugca agugcgagac ugucgccgcg gcgaggccgg uaacucgguc gcccgguggg      600

agucaggagc agcgugcgaa gacgccgcag acgcgaguua ccauaaggac cguacgugug      660

cgucguccgc cgaaaggaaa gcaccgaaag uucaagcaca cgcacgacaa gacugccuua      720

aaggagacgu uaggugccug aggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  5662
<211>  1255
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt10)

<400>  5662
gggagaaagc uuaccauguc guuauucggc uuguuauuau ugacgagugc guuagcaggg       60

cagcggcaag guacacaggc agagucgaac cucucgucga aguuccaguu cucgucgaac      120

aaggagcaga acggugugca ggacccacag cacgagcgua ucaucacggu uucgacaaac      180

gggucgauac acucgccgcg uuucccacac acguacccgc gaaacacugu guuagucugg      240

cgucucguug ccgucgagga gaacguuugg auccaguuaa cuuucgacga gagguucggu      300

uuagaggacc cggaggacga caucugcaag uacgacuucg uugagguaga ggagccuuca      360

gacgguacga ucuugggacg auggugcggg ucggggaccg uucccgggaa gcagauaucg      420

aaggggaacc agauacgaau ccgauucguc ucggacgagu acuucccguc ggagccgggu      480

uucugcauac acuacaacau aguaaugccg caguucacgg aggccguuuc gccgucuguc      540

uuaccgcccu cggcguuacc guuagacuua cucaacaacg cgaucacggc guucucuacg      600

uuagaggacu uaauacguua cuuagagccg gagcgauggc aauuagacuu ggaggacuug      660

uaccgcccca ccuggcaguu acucgguaag gcauucguau ucgggcgaaa gagucgagua      720

guagacuuaa auuuauuaac cgaggagguu cgacuauacu cuugcacucc ccgcaacuuc      780

ucgguuucga uccgagagga gcuuaagcgc acggacacga uauucuggcc ggggugcuua      840

uuggucaaga ggugcggggg uaacugcgcg ugcugccuuc acaacugcaa cgagugccag      900

ugcgugccgu cgaaggucac aaagaaguac cacgaggucu uacaacuucg ccccaagacg      960

ggcgugcgag guuuacacaa gagucuaacu gacguagcgc ucgagcacca cgaggagugc     1020

gacugcgucu gcaggggguc gaccgggggg ugaggacuag uuauaagacu gacuagcccg     1080

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1200

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1255


<210>  5663
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt10)

<400>  5663
gggagaaagc uuaccaugca ccgacuaauc uucguauaca ccuugauaug cgccaacuuc       60

ugcuccugcc gagacacguc ggccacuccc cagucggcua guauaaaggc ccuucguaac      120

gcgaacuugc gucgggacga ccuuuacagg agggacgaga cuauccaggu caagggcaac      180

ggauacgucc aaucgccccg guuccccaac aguuacccgc ggaacuuacu uuugaccugg      240

cguuuacacu cgcaggagaa cacgaggauc caauuaguuu ucgacaacca guucggccuc      300

gaggaggccg agaacgacau augccgauac gacuucguag agguagagga caucagugag      360

accucgacga uaaucagggg gcgguggugc ggccacaagg agguaccccc ucgaaucaag      420

agucgaacca accagaucaa gauaaccuuc aagucggacg acuacuucgu agcaaagccg      480

ggguucaaga uauacuacuc gcucuuagag gacuuccagc cggcggccgc gucggagaca      540

aacugggagu cgguaacguc gucgauaucg ggugugucgu acaacucacc cucggucacc      600

gacccgaccu ugauagccga cgcguuagac aagaagaucg ccgaguucga cacgguagag      660

gacuuguuga aguacuucaa cccggagucg uggcaggagg acuuagagaa cauguacuua      720

gacacgccga gguacagggg gcggucguac cacgaccgca agucgaaggu ggacuuagac      780

cgacuuaacg acgacgcgaa gcgauacucg ugcacaccuc gaaacuacag uguaaacauc      840

agggaggagu uaaaguuagc caacgucgua uucuucccgc ggugcuuauu aguucagcgu      900

ugcgggggca acugcgguug cgggacggug aacuggcgau cuugcacgug caacucgggu      960

aagaccguaa agaaguacca cgagguccuu caguucgagc ccgggcacau aaagcgucgc     1020

ggccgugcga agaccauggc gcucguggac auucaacucg accaccacga gcguugcgac     1080

ugcaucugcu cgucgcgacc uccgcguuga ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  5664
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt10)

<400>  5664
gggagaaagc uuaccauggu aacgcacucg aaguucccgg cggcggguau gaguaggccg       60

uuagacacau cgcuucguuu aaagacauuc ucgucgaaga gugaauacca gcucguuguc      120

aacgcggucc ggaaguugca agaaucaggu uucuauuggu cggcgguaac ggggggggag      180

gcaaauuuau uauugucggc ggagccagcg gggacauucu uaauccguga cucgucugac      240

cagcggcacu uuuuuacauu aucagugaag acacaaucgg guacgaagaa ccuucgaaua      300

cagugcgagg gcggaaguuu cucguugcag agugacccgc gaucuacaca gccggucccu      360

cgauucgacu gcguauuaaa guugguucac cauuacaugc ccccaccggg ggcuccgagu      420

uucccgucac cgccgacgga gccgaguucg gagguaccgg agcagccauc ggcgcagccu      480

uuaccggguu cgccgccucg acgcgcguac uacauauacu cgggggguga aaagauucca      540

cucguauuau cgaggccuuu aucgucgaac guagcgacac uccaacacuu gugccgcaag      600

accguuaacg gacauuuaga cucguacgag aaggucacgc aacucccagg cccgaucagg      660

gaguucuugg accaguacga cgcuccauua ugaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  5665
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt10)

<400>  5665
gggagaaagc uuaccauggu gccgagcgcc gggcaauugg cguuauuugc cuuagggauc       60

guccucgccg ccugucaagc gcucgaaaau ucgaccaguc ccuuaucggc cgaucccccg      120

gucgccgccg ccgucgucag ucacuucaac gauuguccgg acagucauac ccaauuuugu      180

uuucacggga cgugucgcuu ccucguccaa gaagauaaac cggccugcgu gugucacagc      240

ggcuaugucg gggccaggug cgaacacgcc gauuuguuag cggucgucgc cgcgucgcaa      300

aaaaaacaag cgauaacggc gcucgucguc gugaguauag ucgcguuagc cguguugaua      360

auaaccugcg ucuuaaucca uuguugucaa gugaggaagc auugcgaaug guguagagcg      420

uugauaugua gacaugaaaa accgucggcg uuguuaaaag ggcgcacggc cuguugucau      480

agcgagaccg ucgugugagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  5666
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt10)

<400>  5666
gggagaaagc uuaccaugcc cccgucuggu uuacgauuau uacccuuauu guuacccuua       60

uugugguuau uaguauugac ccccgggcga ccggccgccg gcuuaaguac gugcaagacc      120

aucgacaugg aguuaguaaa gcggaagcga auagaggcga uacgagggca gaucuuaucg      180

aaguuacgau uagccagucc gcccucgcag ggcgagguac cgcccgggcc cuugcccgag      240

gccguauuag cguuauacaa caguacccga gaccgaguag cgggugaguc ugcggagccc      300

gagcccgagc ccgaggccga cuacuacgcc aaggagguaa cacgaguauu gaugguagag      360

acccacaacg agaucuacga caaguucaag cagaguacgc acucuaucua cauguucuuc      420

aacacgagug aguuacgaga ggcgguuccc gagcccguau uauuaagucg agcggaguua      480

cgauuauugc gauuaaaguu aaagguagag cagcacguag aguuauacca gaaguacagu      540

aacaacucuu ggcgauacuu aucaaaccgu uuauuagcgc cgucugacag ucccgagugg      600

uuaucuuucg acguaacggg gguaguacga cagugguuaa gucguggggg cgagauagag      660

ggguuccgau ugucagcgca cugcaguugc gacucucggg acaacacguu gcagguagac      720

aucaacggcu ucacgacggg gcgacgaggc gacuuagcca ccauacacgg caugaaccga      780

cccuucuuau uauuaauggc cacgcccuua gagcgugcgc agcacuuaca gucuagucga      840

caccgacgag ccuuagacac caacuacugc uucaguucga ccgagaagaa cugcugcgua      900

cgacaguuau acaucgacuu ccgaaaggac uuagggugga aguggauaca cgagccgaag      960

ggcuaccacg cgaacuucug cuuagggccc ugccccuaca ucuggucguu agacacgcag     1020

uacaguaagg uauuagccuu auacaaccag cacaaccccg gcgccucggc ggccccgugc     1080

ugcguaccgc aggcguugga gcccuuaccc auaguauacu acguaggccg uaagccgaag     1140

guagagcagu uaaguaacau gauaguacga ucgugcaagu gcaguugagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  5667
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt10)

<400>  5667
gggagaaagc uuaccaugca cuacugcgua uuaucugcgu ucuugauauu acacuuaguu       60

accguggcau ugaguuuauc cacuugcagu acguuagaca uggaccaguu caugcgaaag      120

cgaauagagg cuauaagggg ucagauuuug ucgaagcuca aguuaacguc uccuccggag      180

gacuaccccg agccggaaga gguaccgccg gagguaauca guauauacaa cucgacgcga      240

gaccuuuuac aggaaaaggc aucgcgacgc gcagcggcgu gcgagaggga gcguucggac      300

gaggaguacu acgcgaagga aguauacaag aucgacaugc cuccguucuu cccgucggag      360

aacgcgaucc caccuacguu cuaucgaccg uacuuccgca ucgucagguu cgacguaagu      420

gcgauggaga agaacgccuc uaacuuagua aaggcggagu uucgaguauu cagguuacag      480

aacccgaagg cgcgaguucc cgagcagagg aucgaguuau accagaucuu aaagaguaag      540

gaccuuacuu cgccuacgca acgauacaua gacaguaagg uaguaaagac gcgagccgag      600

ggagaguggu uaucguucga cgucacggac gcgguccacg agugguuaca ccacaaggac      660

cgcaaccuug gcuucaagau cagucuccac ugcccgugcu gcacauucgu cccuucgaac      720

aacuauauaa uaccgaacaa gucggaggag uuagaggcuc guuucgcggg aaucgacggg      780

acgucgacgu acacgucggg agaccagaag acgaucaagu cgacgcgaaa gaagaacucg      840

ggaaagacac cgcacuuguu auuaauguug uuaccgucgu acagguuaga gucgcagcag      900

acgaaccgcc gaaagaagcg agcgcuagac gcagcguacu guuuccgaaa cguacaagac      960

aacugcuguu uaaggcccuu auacaucgac uucaagcgcg acuuggguug gaaguggauc     1020

cacgagccua aggguuauaa cgcaaacuuc ugcgcaggcg cgugccccua ccucuggucg     1080

ucggacaccc aacacagucg aguguuaucu cuuuacaaca cgaucaaccc cgaggcgagu     1140

gccucgccgu gcugcgucuc gcaggacuug gagccauuaa cgaucuugua cuacaucggu     1200

aagacgccua agaucgagca guuaucgaac augauaguca aaaguugcaa gugcucauga     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  5668
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt10)

<400>  5668
gggagaaagc uuaccaugaa gaugcacuug cagagggcgu ugguaguauu agcguuauug       60

aacuucgcga cgguaucguu aaguuuaucg acaugcacga cguuggacuu cggccacauc      120

aagaagaagc gcguagaggc gauacggggu cagauauuaa guaaguuacg cuugacgucg      180

ccgccggagc cgacgguaau gacacacgua ccguaccagg uauuagcguu auacaacagu      240

acgagggagu uguuagagga gaugcacggu gagcgcgagg aggguugcac gcaggagaac      300

acggagucgg aguacuacgc gaaggagaua cacaaguucg acaugauaca ggguuuagcg      360

gagcacaacg aguuggcggu augccccaag gggauaacga guaaggucuu cagguucaac      420

guaucgagug uagagaagaa ccgcacgaac uuauucaggg cggaguuccg aguauuaagg      480

gucccgaacc cgucgaguaa gcgaaacgag cagaggauag aguuauucca gauauuacgc      540

cccgacgagc acauagcgaa gcagcgguac auagggggua agaacuuacc cacgcgcggu      600

acggcugagu gguugucguu cgacguaaca gacacgguaa gggagugguu auuacgcagg      660

gagaguaacu ugggcuuaga gauaucgaua cacugcccuu gccacacguu ccagccgaac      720

ggggacauau uagagaacau acacgaggua auggagauaa aguucaaggg uguagacaac      780

gaggacgacc acgggcgagg ggacuugggg agguuaaaga agcagaagga ccaccacaac      840

ccccacuuaa uauugaugau gauaccgccg caccgauuag acaaccccgg ucaggggggg      900

cagcgaaaga agagggcguu agacacgaac uacugcuucc gaaacuugga ggagaacugc      960

ugcguaaggc cguuauacau agacuuccgc caggacuuag gguggaagug gguacacgag     1020

ccgaaggguu acuacgcuaa cuucugcagu gguccgugcc ccuacuugag gucggcagac     1080

acaacgcaca guacgguauu agguuuauac aacacguuga acccggaggc gucggcuagu     1140

ccgugcugcg uaccgcagga cuuagagccc uuaacaauau uguacuacgu agggagaacg     1200

ccgaagguag agcaguuauc gaacauggua guaaagucgu gcaagugcag uugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  5669
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt10)

<400>  5669
gggagaaagc uuaccauggc cccgguggcg gucugggcgg cuuuagcggu agggcuugag       60

cuuugggcgg ccgcgcacgc guuaccggcg caggucgcgu ucacgcccua cgcucccgag      120

ccggguucaa cgugcagguu gcgcgaguac uacgaccaaa cugcgcagau gugcugcucg      180

aagugcuccc cgggacagca cgcgaaggua uucugcacca aaacaucaga cacggugugc      240

gacucgugcg aggacucgac uuacacgcaa uuauggaacu gggugcccga gugccucucg      300

ugcggaucgc gaugcucguc agaccaagua gagacccagg ccugcacgcg cgagcaaaac      360

cggaucugca cgugccgccc gggcugguac ugcgccuugu cgaagcagga ggguugccga      420

cucugcgcgc cccuccgaaa gugccggccg gguuucgggg uagcgcgacc ugggacggag      480

acgucggacg uagucugcaa gccgugcgcg cccggaacau ucucuaacac gacaucgucu      540

accgacaucu gccgcccgca ccagaucugc aacgucguug caaucccggg gaacgcgagu      600

auggacgcgg uaugcacauc gacgucgccg acgcgcucaa uggcgccggg cgccgugcac      660

cuuccgcagc ccguaucgac gcggucgcag cacacccaac cgacgccgga gccgucgacc      720

gcgccgucga cuucguuccu uuuacccaug gggcccucgc cgcccgcgga gggcucgacc      780

ggugacuucg cguugccggu aggguuaauc gugggcguca cggcguuagg guuguuaauc      840

aucggcgucg uaaacugcgu gauaaugacg cagguaaaga agaagccgcu gugcuugcag      900

cgagaggcga aggugccgca cuuaccggcc gacaaggccc guggcacgca gggucccgag      960

cagcagcacu uauuaauuac cgcgccgucg ucgaguucga guucguugga gucgagcgca     1020

ucggcccuag acaggcgagc ccccacgcga aaccagccgc aggcgccggg uguggaggcg     1080

ucuggggccg gcgaggcccg ugccucgacc ggaucgucgg acucgucgcc gggcggacac     1140

gguacacagg uaaacguaac uugcaucguu aacguaugcu cgucgucgga ccacucgagu     1200

cagugcucga gucaggcguc gucgacgaug ggggacacug acucgucgcc cucagagagu     1260

ccuaaggacg agcagguccc guucucgaag gaggagugcg ccuuccguag ucaacucgag     1320

acaccggaga cgcuccucgg aucaacggag gagaagccgu uacccuuagg cguuccggac     1380

gcggggauga agccgucgug aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  5670
<211>  730
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt10)

<400>  5670
gggagaaagc uuaccaugcc cguaaugcgc uuauuuccau guuucuugca guuauuagcg       60

ggcuuggccu uacccgcagu accaccgcaa caaugggcuc ucucggcagg gaacgguagu      120

ucggaaguug aggucguccc guuccaggag gucugggguc gaaguuacug cagggcccuu      180

gagcgccucg uggacguagu aagugaguau ccgagugagg uagagcauau guucucgccu      240

aguugcguuu cuuuauugag guguacaggu ugcugcggug acgagaacuu acacugcgua      300

cccguagaga ccgccaacgu aacuaugcaa uuauugaaga uucgaucggg agaccgucca      360

ucguacguag aguuaaccuu uagucagcau guccguugcg agugccgucc gcuucgcgag      420

aaaaugaagc ccgagcgucg aaggccuaaa gggcgcggga agcggcgcag ggagaaacag      480

cgaccuacgg acugucacuu gugcggggac gcggucccgc gacgcugagg acuaguuaua      540

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua      600

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      720

caccagaauu                                                             730


<210>  5671
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt10)

<400>  5671
gggagaaagc uuaccaugac cgaccgccag accgacacgg cccccucgcc guccuaccac       60

cucuuacccg gccggcgccg gaccguggac gccgcggccu cgcgcgggca gggccccgag      120

cccgcccccg ggggcggggu cgagggcgug ggcgcccgcg ggguggccuu aaaguuauuc      180

guccagcucu uaggcugcuc ccgguucggg ggcgcggugg ugcgggccgg ggaggccgag      240

cccucgggcg ccgcgcgcuc cgccucgucc ggccgggagg agccccagcc cgaggagggg      300

gaggaggagg aggagaagga ggaggagcgc ggcccgcagu ggcgguuagg ggcccgcaag      360

cccggcucgu ggaccggcga ggccgccguc ugcgcggacu ccgcccccgc cgcccgggcc      420

ccgcaggcgc ucgcccgcgc cucggggcgg ggcgggcgcg uggcccggcg cggcgccgag      480

gaguccgggc cgccccacuc gcccucccgg cgcggcucgg cgucccgggc cggccccggg      540

cgcgccucgg agaccaugaa cuucuuauua uccugggugc acuggucgcu cgccuuauua      600

cucuacuuac accacgccaa guggucccag gcggccccga uggccgaggg cgggggccag      660

aaccaccacg aggucgugaa guucauggac guguaccagc gcucguacug ccaccccauc      720

gagacguuag ucgacaucuu ccaggaguac cccgacgaga ucgaguacau cuucaagccc      780

ucgugcgugc cgcucaugcg gugcgggggc ugcugcaacg acgagggcuu agagugcgug      840

cccaccgagg aguccaacau caccaugcag aucaugcgca ucaagcccca ccaggggcag      900

cacaucggcg agaugucguu cuuacagcac aacaagugcg agugccggcc caagaaggac      960

cgcgcccggc aggagaagaa guccguccgc gggaagggca aggggcagaa gcggaagcgc     1020

aagaaguccc gguacaaguc guggucggug uacgugggcg cgcgcugcug ccucaugccg     1080

ugguccuuac ccggccccca ccccugcggg ccgugcucgg agcggcgcaa gcacuuauuc     1140

guccaggacc cgcagacgug caagugcucg ugcaagaaca cggacucgcg gugcaaggcg     1200

cgccagcucg aguuaaacga gcggacgugc cgcugcgaca agccgcggcg cugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  5672
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt10)

<400>  5672
gggagaaagc uuaccaugaa cuucuuauug ucgugggucc acuggaguuu agcguuauug       60

uuauacuuac accacgcgaa guggucgcaa gcagcgccga uggcggaggg ggguggucaa      120

aaccaccacg agguaguaaa guucauggac guguaccaga ggucguacug ccacccgaua      180

gagacguugg uagacauauu ccaagaguac ccggacgaga ucgaguacau cuucaagccg      240

ucgugcguac cguuaaugcg cugcgguggu ugcugcaacg acgaggguuu agagugcguc      300

ccuacggagg agaguaacau cacuaugcag auaaugagga uuaagccgca ucaagggcag      360

cacauagggg agaugucguu cuugcagcau aacaagugcg agugccgacc gaagaaggac      420

cgagcgcgac aggagaagaa gaguguaagg gguaaaggga agggucaaaa gcgcaagagg      480

aaaaagaguc gauacaaguc guggucggua uacgucgggg ccaggugcug cuuaaugccg      540

uggucguuac cagggccgca cccgugcggg ccgugcucgg agcgcaggaa gcacuuauuc      600

guacaggacc cacagacgug caagugcagu ugcaagaaca cggacucgcg uugcaaggca      660

cgacaguuag aguuaaacga gcgaacgugc cggugcgaca agccucgaag gugaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  5673
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt10)

<400>  5673
gggagaaagc uuaccauguc gccguuauug aggagguuau uauuggcggc cuuguuacaa       60

uuagcgccgg cgcaagcgcc ggugagucaa ccggacgcgc cggggcauca acgcaagguc      120

gucagcugga ucgacgucua caccagggcc acgugucaac cgagagaagu cgucgucccg      180

cucaccgucg aauugauggg gacggucgcg aagcaauuag ucccgucgug ugucaccguc      240

caaaggugcg ggggguguug uccggaugac ggguuagaau gcgucccgac cggccaacau      300

caggugagaa ugcaaauauu gaugauaaga uaucccucgu cgcaauuagg cgaaaugagu      360

uuagaggagc auucgcaaug cgagugucgc ccgaagaaga aagauucggc cgucaaaccg      420

gaucgcgccg cgaccccgca ucauaggccg caaccgagga gcguccccgg gugggauagc      480

gcgccggggg ccccgagucc ggccgauaua acgcacccga ccccggcgcc ggggccgagc      540

gcgcaugccg ccccgucgac gacgucggcg uuaacgccgg ggccggcggc cgcggccgcg      600

gaugcggccg ccaguagugu cgcgaaaggg ggcgccugag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  5674
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt10)

<400>  5674
gggagaaagc uuaccaugca ccucuuaggg uucuucagcg ucgccugcuc cuuacuggcg       60

gcggcccucc ugcccgggcc gcgcgaggcc ccggcggcgg cggcggcguu cgagagcggc      120

cuggaccucu ccgacgccga gccggacgcg ggggaggcga ccgccuacgc cucgaaggac      180

uuagaggagc agcugcgguc cgucagcucc guggacgagc ucaugaccgu gcuguacccc      240

gaguacugga agauguacaa gugccaguug cgcaagggcg gguggcagca caaccgggag      300

caggcgaacc ucaacagccg cacggaggag accaucaagu ucgcggccgc ccacuacaac      360

accgagaucc ucaaguccau cgacaacgag uggcggaaga cccagugcau gccgcgcgaa      420

gucugcaucg acgucggcaa agaguucggc guggccacga auacguuuuu caagccgccc      480

ugcgucagug uguaucggug cgggggcugu uguaacuccg aaggguuaca auguaugaau      540

acgucgaccu cguauuuauc gaaaacgcug uucgagauca ccguccccuu gucccagggg      600

ccgaagcccg ucaccauauc guucgcgaac cauaccucgu gucgcuguau gagcaaguua      660

gacguguauc gccaggugca cucgaucauc cggcggaguu uacccgcgac guugccccaa      720

ugccaagccg ccaauaaaac guguccgacg aacuauaugu ggaacaacca uauaugucgc      780

uguuuagccc aagaggacuu cauguucagu uccgacgccg gggacgauag caccgacggc      840

uuucacgaua uaugcggccc caauaaagaa uuagacgagg aaacgugcca augcgucugu      900

cgggcggggu ugcgccccgc gucgugcggc ccgcauaagg agcucgaucg gaauagcugu      960

caaugcgugu gcaagaauaa guuguuuccg ucgcagugcg gggcgaaucg cgaguucgac     1020

gagaauacgu gucaaugcgu gugcaagcgg acguguccgc gcaaccagcc guugaacccc     1080

ggcaagugcg cgugcgagug caccgagucg ccgcaaaagu gucuccugaa gggcaagaaa     1140

uuucaucauc agaccuguuc gugcuaucgg cgccccugca ccaaucggca aaaagccugc     1200

gaacccgggu ucagcuacuc cgaggagguc ugccgcugcg ugcccagcua cuggaagcgc     1260

ccgcagaugu cgugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     1320

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  5675
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt10)

<400>  5675
gggagaaagc uuaccaugua cagggaaugg gucguaguca acgucuucau gauguuauac       60

guacaauuag uacaagguuc gucgaacgag cacgguccgg ucaagcguuc gucgcaaucg      120

acguuagagc guucggagca gcagauacga gcggcgucgu cguuagagga guugcuacgg      180

auaacgcacu cggaggacug gaaguuaugg cgaugucgau uacgcuuaaa gucguucaca      240

ucgauggacu cgaggucggc uucgcaccgc ucgacgcggu ucgccgcgac auucuacgac      300

auagagacgu uaaaggucau cgacgaggag uggcagcgca cgcagugcuc gccgagggag      360

acuugcgucg aggucgcguc agaauugggu aagucgacua acacguuuuu caagccuccg      420

ugcguuaacg ucuuccguug cggggguugc ugcaacgagg agucguuaau cugcaugaac      480

acaaguacgu cauacaucuc gaagcaauua uucgagaucu cggucccauu aaccucgguc      540

ccggaguugg ugccgguaaa gguagcgaac cacacggggu gcaagugcuu accgacggcu      600

ccgcgacacc cguacaguau aauacgacgg ucgauacaga uucccgagga ggaccgaugc      660

agucacucga agaagcuaug cccaaucgac augcucuggg acaguaacaa gugcaagugc      720

guauuacagg aggagaaccc cuuggcgggg acggaggacc acucgcacuu gcaggagccg      780

gcguugugcg gaccgcacau gauguucgac gaggaccggu gcgagugcgu augcaagacu      840

ccgugcccga aggacuugau ucagcacccu aagaacugcu cgugcuucga augcaaggag      900

ucguuagaga cgugcugcca gaagcacaag uuguuccacc cggauacaug caguugcgag      960

gaccgaugcc cguuccacac acgacccugc gcgucgggua agacggcuug cgcgaagcac     1020

ugccgauucc cuaaggagaa gcgagcggca caggguccgc acucucguaa gaacccguga     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  5676
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt10)

<400>  5676
gggagaaagc uuaccauggg uaaaggugac ccgaaaaagc cacgcgguaa gaugaguucg       60

uaugcguucu ucguccaaac gugccgagag gaacacaaga aaaagcaccc ggacgcgucg      120

guaaacuucu cggaguucuc aaaaaagugc uccgaacgcu ggaagacgau gucggcgaaa      180

gagaaaggua aauuugaaga uauggcgaaa gcggacaagg cgcgcuacga gagggagaug      240

aagacauaua uaccgccgaa gggugagacc aagaaaaagu ucaaggaccc gaacgcgccg      300

aagcggccgc cgucugcguu uuuccuuuuc uguucggagu accgcccgaa gauaaaggga      360

gagcacccgg gccuuucgau aggcgacgua gcgaaaaagu ugggugaaau guggaauaac      420

acggcggcgg acgauaaaca gccauaugaa aagaaagcag cgaagcucaa ggaaaaguac      480

gagaaagaua ucgcggcaua ucgagcaaaa gguaaaccgg acgcggcgaa gaaaggugua      540

guaaaagcag aaaagucgaa gaaaaagaaa gaggaagagg aagaugaaga ggacgaggaa      600

gaugaagagg aagaggaaga ugaagaggac gaggacgagg aagaggacga ugacgaugaa      660

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc      720

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5677
<211>  1012
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt10)

<400>  5677
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacu       60

ccgacgaaac cggcuucgaa cacucaggcc ucugggucuc cguacuagcc ggccuccucc      120

ucggcgccug ccaagcccac cccauccccg acuccucacc ccuccuacaa uucggcggcc      180

aaguccgcca acgcuaccua uacaccgacg acgcccaaca aaccgaagcc caccucgaaa      240

uccgcgaaga cggcaccguc ggcggcgccg ccgaccaauc ccccgaaucc cuacuacaac      300

ucaaagcccu caaaccugga gucauccaaa uacucggcgu caaaaccucc cgcuuccucu      360

gccaacgccc cgacggagcc cucuacggcu cccuccacuu cgacccagaa gccugcucuu      420

uccgagaacu ccucuuagaa gacggcuaca acgucuacca aucugaagcc cacggccucc      480

cccuucaccu ccccggaaac aaaucacccc accgcgaccc cgcaccccgc ggcccagcca      540

gauuccuccc ccuccccggc cucccaccag cccuccccga accacccggc auccucgcac      600

cccaaccacc cgacgucggc uccuccgacc cccucucaau ggucggcccc ucccaaggcc      660

gcucccccuc auacgccuca ugaggacuag ugcaucacau uuaaaagcau cucagccuac      720

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      780

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      840

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      960

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1012


<210>  5678
<211>  1792
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt10)

<400>  5678
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcauu       60

cguucccgcc guuauuauua uuauuauuuu ggggggucgu cagccauucg uuuccggcca      120

ccuuggagac ccaggaacag gacgucgauc ucgugcaaaa guauuuagag aaguauuaua      180

auuuaaaaaa cgacggccgc caggucgaga aaagacgcaa cucggggccg gucgucgaga      240

agcucaaaca gaugcaagag uuuuucggcu uaaaggucac cggcaagccg gacgccgaga      300

cguuaaaagu caugaaacaa ccgcgcugcg gggucccgga cgucgcccaa uucguguuga      360

ccgaaggcaa uccgaggugg gaacagaccc acuuaacgua ucgcaucgag aacuauaccc      420

cggaccuccc gcgcgccgac gucgaucacg cgaucgaaaa ggcguuucag uuguggucga      480

acgugacccc guuaaccuuu acgaaaguga gcgaagggca ggccgauaua augaucagcu      540

ucgugcgcgg ggaccacaga gauaauagcc cguucgacgg gccggggggg aacuuggccc      600

acgccuucca gccggggccg gggaucgggg gcgacgccca cuucgacgag gacgagcgcu      660

ggacgaauaa cuuucgcgaa uauaaucucc acagggucgc cgcccacgag uuggggcaca      720

gcuugggguu gagucacagc accgacauag gcgcccucau guauccgucg uauacguuuu      780

cgggggacgu ccaauuggcc caagacgaua ucgacgggau acaggcgauc uacgggagga      840

gucagaaccc ggugcaaccg auagggccgc agacgccgaa ggccugcgau ucgaaauuga      900

cguucgacgc caucaccacc aucagagggg aggucauguu uuucaaggau cgcuuuuaua      960

ugaggaccaa cccguuuuau cccgaggucg aauugaacuu uaucagcguc uuuuggccgc     1020

aguuaccgaa cggcuuggag gccgccuaug aguucgcgga ucgcgacgag gugagauucu     1080

uuaagggcaa caaauauugg gccguccaag ggcaaaacgu cuugcauggg uauccgaaag     1140

auauauauuc gaguuucggg uuuccgcgca ccgucaaaca cauagacgcc gccuugagcg     1200

aagagaauac cgggaagacg uauuuuuucg ucgccaauaa guauuggcgc uacgacgagu     1260

acaagaggag cauggacccg ggguacccga agaugaucgc ccacgauuuc ccggggaucg     1320

ggcauaaggu cgacgccguc uuuaugaagg acggguucuu uuacuuuuuc cacgggaccc     1380

gccaguauaa guucgacccg aagaccaaac gcauccucac cuugcaaaag gccaacucgu     1440

gguuuaauug ucgcaagaac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1740

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1792


<210>  5679
<211>  3448
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt10)

<400>  5679
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

gcaagugccu gagcaagcgg cucaugcugg ccaucaccau ggccaccauc uucacgguga      120

acuccacccu gcccaucuac gcggccgucg acaagaacaa cgccaccgcc gccgugcaga      180

acgagagcaa gcgcuacacc guguccuacc ucaagacgcu gaacuacuac gaccuggucg      240

accuccuggu gaagaccgag aucgagaacc ugccggaccu cuuccaguac agcuccgacg      300

cgaaggaguu cuacggcaac aagacccgga ugagcuucau cauggacgag aucgggcgcc      360

gggcgcccca guacaccgag aucgaccaca agggcauccc cacgcuggug gaggucgugc      420

gcgccggguu cuaccugggc uuccacaaca aggagcucaa cgagaucaac aagcgguccu      480

ucaaggagcg cgugaucccc agcauccugg ccauccagaa gaacccgaac uucaagcugg      540

ggaccgaggu ccaggacaag aucguguccg ccaccggccu ccuggccggc aacgagaccg      600

ccccgcccga gguggucaac aacuucacgc ccauccugca ggacugcauc aagaacaucg      660

accgguacgc ccucgacgac cucaagagca aggcccuguu caacgugcuc gcggccccga      720

ccuacgacau caccgaguac cugcgcgcca ccaaggagaa gcccgagaac acgcccuggu      780

acgggaagau cgacggcuuc aucaacgagc ugaagaagcu cgcccuguac gggaagauca      840

acgacaacaa cuccuggauc aucgacaacg gcaucuacca caucgcgccc cuggggaagc      900

uccacagcaa caacaagauc ggcaucgaga cccugaccga ggugaugaag gucuacccgu      960

accuguccau gcagcaccuc cagagcgccg accagaucaa gcggcacuac gacuccaagg     1020

acgccgaggg caacaagauc ccccuggaca aguucaagaa ggaggggaag gagaaguacu     1080

gccccaagac cuacacguuc gacgacggca aggugaucau caaggccggg gcccgcgugg     1140

aggaggagaa ggucaagcgg cuguacuggg ccagcaagga ggugaacucc caguucuucc     1200

gcguguacgg caucgacaag ccccucgagg agggcaaccc ggacgacauc cugaccaugg     1260

ucaucuacaa cagccccgag gaguacaagc ugaacuccgu gcucuacggg uacgacacca     1320

acaacggcgg gauguacauc gagcccgagg gcaccuucuu cacguacgag cgggaggcgc     1380

aggagagcac cuacacccug gaggagcugu uccgccacga guacacccac uaccuccagg     1440

ggcgguacgc cgugcccggc caguggggcc gcacgaagcu guacgacaac gaccggcuga     1500

ccugguacga ggagggcggg gccgagcugu ucgccgggag cacccgcacc uccggcaucc     1560

ugccgcgcaa gagcaucguc uccaacaucc acaacacgac ccggaacaac cgcuacaagc     1620

ugagcgacac cgugcacucc aaguacgggg ccagcuucga guucuacaac uacgcgugca     1680

uguucaugga cuacauguac aacaaggaca ugggcauccu caacaagcug aacgaccugg     1740

ccaagaacaa cgacgucgac ggcuacgaca acuacauccg ggaccucucc agcaacuacg     1800

cccugaacga caaguaccag gaccacaugc aggagcgcau cgacaacuac gagaaccuga     1860

ccgugcccuu cguggccgac gacuaccugg uccggcacgc guacaagaac cccaacgaga     1920

ucuacuccga gaucagcgag guggccaagc ucaaggacgc caaguccgag gugaagaagu     1980

cccaguacuu cagcacguuc acccugcgcg ggagcuacac cggcggggcc uccaagggca     2040

agcuggagga ccagaaggcc augaacaagu ucaucgacga cagccucaag aagcuggaca     2100

ccuacuccug gagcggguac aagacccuga cggcguacuu caccaacuac aaggucgacu     2160

ccagcaaccg ggugaccuac gacguggucu uccacggcua ccuccccaac gagggcgaca     2220

gcaagaacuc ccugccguac gggaagauca acggcaccua caaggggacg gagaaggaga     2280

agaucaaguu cagcuccgag ggcagcuucg accccgacgg caagaucgug uccuacgagu     2340

gggacuucgg ggacggcaac aagagcaacg aggagaaccc cgagcacucc uacgacaagg     2400

uggggaccua caccgucaag cugaagguga ccgacgacaa gggcgagagc uccgugagca     2460

cgaccaccgc cgagaucaag gaccucuccg agaacaagcu gcccgucauc uacaugcacg     2520

ugcccaagag cggggcccug aaccagaagg uggucuucua cggcaagggc accuacgacc     2580

ccgacggguc caucgccggc uaccaguggg acuucgggga cggcagcgac uucuccagcg     2640

agcagaaccc cucccacgug uacacgaaga agggggagua caccgugacc cuccgcguca     2700

uggacagcag cggccagaug uccgagaaga ccaugaagau caagaucacg gacccggugu     2760

accccaucgg caccgagaag gagcccaaca acagcaagga gaccgccucc gggcccaucg     2820

ugccgggcau ccccgucagc gggaccaucg agaacacguc cgaccaggac uacuucuacu     2880

ucgacgugau cacccccggc gaggugaaga ucgacaucaa caagcugggg uacggcggcg     2940

cgaccugggu cguguacgac gagaacaaca acgccgugag cuacgccacc gacgacgggc     3000

agaaccuguc cggcaaguuc aaggccgaca agcccgggcg guacuacauc caccucuaca     3060

uguucaacgg cagcuacaug ccguaccgca ucaacaucga gggguccguc ggccggugag     3120

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     3180

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     3240

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     3300

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     3420

aaaggcucuu uucagagcca ccagaauu                                        3448


<210>  5680
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt10)

<400>  5680
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ucacgaaguu guuaccggcg uuauuauuac aacacguguu guuacacuug uuguuauugc      120

cgauagcgau accguaugcc gaagggcagc gcaagcgccg caauaccauc cacgaguuua      180

agaagagugc caaaaccacg uugauaaaga ucgacccggc cuuaaaaauc aagacgaaaa      240

aggucaacac cgccgaucag ugcgccaacc gcugcacccg caacaagggg uugccguuua      300

ccuguaaagc cuucgucuuc gacaaggccc gcaagcaaug uuugugguuu ccguuuaacu      360

cgaugagcuc gggggucaag aaggaguucg ggcacgaguu cgauuuguau gagaauaagg      420

auuauauccg caauuguaua aucgggaaag ggaggucgua uaaagggacc gucagcauaa      480

ccaaaucggg gauaaaaugc caaccguggu cgaguaugau cccgcaugag cauucguucc      540

ucccgagcuc guacagaggg aaggauuugc aagagaauua uugcaggaac ccgaggggcg      600

aggagggcgg gccguggugc uuuaccucga acccggaagu cagguaugag gugugcgaua      660

ucccgcaaug cagcgagguc gaguguauga cguguaacgg cgaaucguac aggggguuga      720

uggaccacac cgagagcggg aaaaucugcc aaagguggga ccaccaaacc ccgcauagac      780

auaaauuucu cccggagcgc uauccggaua aaggguucga cgacaacuac uguaggaacc      840

cggacgggca accccgcccg ugguguuaua ccuuggaucc gcauacgagg ugggaauauu      900

gcgccaucaa aaccugugcc gauaacacca ugaacgauac cgacgucccg cucgagacca      960

ccgaguguau acaggggcag ggggaggggu aucgcgggac cgugaacacg aucuggaacg     1020

ggaucccgug ccaaaggugg gacagccaau auccgcauga acacgauaug accccggaga     1080

acuuuaaaug uaaagauuug agggagaacu auuguaggaa cccggacggc agcgagagcc     1140

cguggugcuu cacgaccgac ccgaauauaa gggucgggua uuguagucag aucccgaauu     1200

gcgacaugag ccacgggcaa gacugcuaua ggggcaacgg gaaaaacuac auggggaauc     1260

ucagucagac ccgcagcggg uugaccugca gcauguggga uaaaaauaug gaggaucucc     1320

acaggcacau auuuugggag ccggacgccu cgaaauuaaa cgaaaacuau uguaggaacc     1380

cggacgacga cgcccacggg ccgugguguu auaccgggaa cccguugauc ccgugggacu     1440

auuguccgau caguaggugc gagggggaca cgaccccgac caucgugaac cucgaucacc     1500

cggucaucag cugcgcgaag accaagcagc ucagggucgu caacggcauc ccgaccagga     1560

ccaauaucgg guggaugguc ucgcuccgcu aucgcaacaa gcacauaugu ggggggagcc     1620

ucaucaaaga aucguggguc uugaccgcca ggcaaugcuu uccgagcagg gaucucaagg     1680

acuacgaggc cugguugggg auccacgacg ugcaugggcg cggggacgaa aaguguaagc     1740

aagucuugaa cgucagucaa uuagucuacg ggccggaggg gagcgacuua guccucauga     1800

aauuggcgcg cccggccgug uuagacgacu ucgucucgac caucgaccuc ccgaauuacg     1860

gguguaccau cccggagaaa acgucguguu cggucuaugg guggggguau accgggcuca     1920

uaaauuacga cggguugcuc agggucgccc acuuguauau cauggggaac gaaaaguguu     1980

cgcaacacca caggggcaaa gucaccuuaa acgaaagcga gaucugcgcc ggcgccgaga     2040

aaaucgggag cgggccgugc gaaggcgacu auggggggcc guuggucugc gaacagcaca     2100

aaaugcgcau ggucuugggg gugaucgucc cggggagggg gugcgcgauc ccgaacaggc     2160

cggggaucuu cgugaggguc gccuacuacg ccaaguggau ccauaagauc auccucaccu     2220

auaaaguccc gcaaagcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5681
<211>  958
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt10)

<400>  5681
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggua       60

cguggauacu cuucgcgugc uuguuaggug cggcguucgc gaugccguua ccgccgcacc      120

caggccaccc gggauacauc aacuucucgu acgaggucuu aacgccgcuc aagugguacc      180

agaguauccg accuccuuac cccucguacg gauacgagcc gauggggggu ugguuacacc      240

accagauaau accaguauug agucagcaac acccgccaac gcacacuuua cagccgcacc      300

accacauccc cguagucccc gcgcagcaac cggucauccc gcaacagccg augaugccgg      360

uacccgggca gcacucgaug acaccuaucc agcaccacca accgaacuug ccgccgccgg      420

cgcagcaacc cuaccagcca cagccggucc agccucaacc ccaccagccu augcagccuc      480

agccgccggu acacccgaug cagccguuac caccgcagcc cccguuaccg cccauguucc      540

cgaugcaacc ccucccgccg auguuaccgg acuuaacguu agaggcgugg ccuucgacgg      600

acaagacgaa gcgcgaggag guugacugag gacuagugca ucacauuuaa aagcaucuca      660

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      720

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      780

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      900

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu        958


<210>  5682
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt10)

<400>  5682
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgu       60

ugccgccgca uccgggucac ccgggguaua uaaacuucuc guaugagguc uugacgccgc      120

ucaaguggua ccaaucgauu cgcccgccuu acccgaguua uggguacgag ccgauggggg      180

gguggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga      240

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa      300

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa      360

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  5683
<211>  961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt10)

<400>  5683
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggua       60

cauggauauu auucgcgugc uuggucggug cugcauucgc aaugccauua ccuccccacc      120

caggccaccc gggguacauu aauuucucgu acgagguauu aacgccgcuu aaaugguacc      180

agaguaugau caggccgccg uacucgucgu acggauacga acccaugggg gguugguuac      240

aucaccagau aauaccggua gucucgcagc agcacccguu aacgcacacg uugcaaucgc      300

accaccacau accgguagua ccggcgcagc aaccucgcgu uaggcagcag gcguuaaugc      360

cgguaccggg gcagcagucg augacaccga cccagcacca ccagccgaac uuaccauuac      420

ccgcucaaca gccauuccag ccgcaacccg uccagccgca accccaucag ccgaugcaac      480

cgcaaccgcc gguacagccg augcagccgu uguuaccgca gccgccguug ccacccaugu      540

ucccguuacg cccuuuaccu ccgaucuuac cggacuuaca cuuagaggca uggccggcga      600

cggacaagac gaagcaggag gagguagacu gaggacuagu gcaucacauu uaaaagcauc      660

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      720

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      780

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      900

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      960

u                                                                      961


<210>  5684
<211>  520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt10)

<400>  5684
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgu       60

ugccgccgca cccgggccau ccgggguaca uaaauuuuuc guacgaaguc uugacgccgc      120

ucaaauggua ucaaucgaug auccgcccgc cguauagcag uuacggguau gaaccgaugg      180

ggggguggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      240

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      300

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      360

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      480

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            520


<210>  5685
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt10)

<400>  5685
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gagucgcgcg auugccauug cucuuagguu uguuauuauu accacgcccg gggaggcccc      120

ucgacuuagc ggacuacacg uacgacuugg cagaggagga cgacucugaa ccuuuaaacu      180

acaaggaccc gugcaaggcu gccgcguucu uaggggacau agcguuggac gaggaggacu      240

uacgcgcuuu ccaaguccag caggcgguug acuuaaggcg ccacacggcg cggaaaaguu      300

cgaucaaggc ggcgguaccc gggaacacaa guacgccguc gugccaaagu acaaacggac      360

aaccacagcg cggggcgugc ggacgguggc gagggagguc gaggaguagg cgagcagcca      420

ccucgcgucc cgagcgggua uggccggacg guguaauucc auucguaaua gguggcaacu      480

ucacgggaag ucagcgggcg guauuccgcc aggcgaugcg acacugggag aaacacacau      540

gcguuacguu cuuggagcga accgacgagg acucguacau aguauuuacg uaccguccau      600

gcggcugcug caguuacgua gggcgaaggg guggcggucc gcaagcgauc ucgauaggua      660

agaacugcga caaguucggu aucguaguuc acgaguuagg ucacguugua gguuucuggc      720

acgagcacac gcgaccugac cgcgacaggc acgucaguau aguccgcgag aacauacagc      780

cgggacagga guacaacuuc uuaaaaaugg agccgcaaga gguugagucg uugggugaga      840

cguacgacuu cgacucgaua augcacuacg cgcgaaacac guucucgcgc gggauuuucu      900

uagacacaau aguuccgaaa uacgagguaa acggcgucaa gccgccgaua ggccagcgga      960

cucgcuuguc gaagggugac auagcgcagg cgcggaaguu guauaagugc ccggcgugcg     1020

gugagacauu acaggacucg acgggaaacu uuaguucgcc cgaguacccu aacggcuacu     1080

cggcgcacau gcacugcguc uggcgaauau cgguaacucc gggggagaag auuauuuuaa     1140

auuucacuuc auuggauuua uauaggucgc gauuauguug guacgacuac guagaaguaa     1200

gggacggguu uuggcguaag gccccuuugc gugggcgauu cugcggaucg aaguuaccgg     1260

agccgauagu aaguacggac ucgcguuuau ggguagaguu ccgaaguucg aguaacuggg     1320

uagguaaggg uuucuucgcc guuuacgagg caauaugcgg uggggacgua aagaaggacu     1380

acggucauau acagucuccg aauuacccgg acgacuacag gccuaguaag guauguauau     1440

ggcgcaucca agucucggag ggauuccaug uuggguugac guuucagagu uucgagauag     1500

agaggcacga cucgugcgcg uacgauuacu uagagguaag ggacggacau ucggagucga     1560

guacuuuaau aggacgauac ugcgguuacg agaagccgga cgacauaaag ucgacuucgu     1620

cgcgauugug guuaaaguuc guuucggacg gaaguauaaa caaggcaggu uucgcgguua     1680

acuucuuuaa ggagguagac gagugcucgc gaccgaaccg aggcgguugc gagcaacgau     1740

gcuuaaacac guugggaucu uacaaaugcu cuugcgaccc ggguuacgag uuggcgccgg     1800

auaagaggcg augcgaggcg gcaugcgggg guuucuuaac aaaguugaac gguucgauaa     1860

caucgcccgg guggccgaag gaguacccgc cgaacaagaa cugcauaugg caauuagucg     1920

cgccgacaca auaccggauu ucguuacagu ucgacuucuu cgagacggag gguaacgacg     1980

ucuguaagua cgacuucguc gagguccgau cggguuugac ugcggacuca aaguuacacg     2040

guaaguucug cggcucggag aagccggagg uaauuacauc gcaguacaac aacaugcgag     2100

ucgaguucaa gucggacaac acgguaagua agaagggguu caaggcacac uucuucucgg     2160

auaaggacga guguucgaaa gacaacgggg guugccaaca ggacugcgua aacaccuucg     2220

guucguacga gugucagugc cgaucggguu ucguauuaca cgacaacaag cacgacugca     2280

aggaggcagg augcgaccau aaggucacgu cgacuucggg gacgauaacg ucgccgaacu     2340

ggccggacaa guacccgucg aagaaggagu gcaccugggc gaucucguca acuccggguc     2400

aucgaguuaa guugacguuc auggagaugg auauugaguc gcagcccgag ugcgcguacg     2460

accacuuaga gguauucgac gggcgugacg cgaaagcacc gguauuagga agguucugcg     2520

guucgaagaa acccgaaccg guuuuggcga cgggaagucg uauguucuua cgguucuacu     2580

cggacaauag uguacaacgu aagggguucc aagcaucgca ugcgacggag ugcggugguc     2640

agguccgagc ggacguuaaa acgaaagacu uauacucgca cgcgcaguuc ggggacaaua     2700

acuacccggg cgggguugac ugcgaguggg uuauagucgc agaggagggg uacgguguag     2760

aguuaguauu ccagacuuuc gaggucgagg aggagacgga cugcgguuac gacuacaugg     2820

aguuauucga cgguuacgac ucgacggcgc cacgauuagg uagguacugc gggucgggac     2880

cgccggagga gguauacuca gccggugaca guguauuagu caaguuucac ucugacgaca     2940

cgauaacgaa gaagggcuuc cacuuacguu acacgaguac gaaguuccag gacacguuac     3000

acucucgaaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  5686
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt10)

<400>  5686
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucg       60

cgggcacgag guguuuguug gcacucuuau ugccgcaagu auuguuaggg ggggccgcgg      120

gguugguccc cgaguuaggg aggcgcaagu ucgccgccgc aagcagcggg aggccgagca      180

gucagccgag cgacgaggua uuaucggagu ucgagcucag auuauugucg auguucgggu      240

uaaaacaacg cccgacgccg ucgcgcgacg cggucguccc gccguauaug uuggacuuau      300

auaggcgcca cagcgggcag cccgggagcc cggcgccgga ccacagacuc gagcgcgcgg      360

cgucgagggc gaacacgguc aggucguucc accaugaaga aagccucgaa gaauugccgg      420

aaacaucggg caaaacgacg agacgcuucu ucuuuaaucu cucgagcaua ccgaccgagg      480

aguuuauaac gagcgccgag uugcaagucu ucagggaaca gaugcaagau gcgcucggga      540

acaauucguc guuccaucac aggauaaaua uauaugaaau aauuaaaccg gccacggcga      600

acagcaaauu cccggucacg cgcuugcucg acacgcgccu cgucaaucag aaugcgucgc      660

gcugggaauc guuugaugua acgccggcgg ucaugagaug gaccgcccag gggcacgcga      720

accauggguu cgucgucgaa gucgcgcacc ucgaggagaa acaaggggua aguaagcgcc      780

auguccgcau uucgcgcagc cuccaccaag augaacacuc guggagccag auucgcccgc      840

ucuuggucac guuugggcau gaugggaaag gccauccguu gcacaaacgc gaaaaaaggc      900

aagcgaaaca caaacaaaga aaaagguuga agaguucgug uaagcgccac ccgcucuacg      960

ucgacuucuc ggacgucggu uggaaugacu ggauagucgc cccgccuggc uaucacgcgu     1020

uuuauugcca cggggaaugc ccguuuccgu uagccgauca uuuaaacagu acgaaucaug     1080

cgauagucca gacacucgua aacagcguca acagcaagau accgaaagcg ugcuguguac     1140

ccacggaauu gucggcgaua agcauguuau auuuggacga gaaugaaaag gucguccuca     1200

aaaauuauca ggacaugguc gucgaggggu guggcuguag gugaggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  5687
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt10)

<400>  5687
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauac       60

cgggaaacag gauguuaaug guaguauugu ugugccaggu auuauugggu ggugccucgc      120

acgcgaguuu gaucccggag accgguaaga agaagguagc ggagauccag ggccacgcgg      180

ggggccgacg uagcggucag ucgcacgagu uauugcgaga cuucgaggcc acgcucuuac      240

agauguucgg ucuucgccga aggccgcagc cgucuaaguc ggccgucaua cccgacuaca      300

ugcgagacuu auaccgauua cagucgggcg aggaggagga ggagcagauc cacaguacgg      360

gguuagagua cccggagcgu ccggccucgc gagcgaacac gguccgcucg uuccaccacg      420

aggagcacuu ggagaacaua ccgggcaccu cggagaacag ugcguucaga uucuuauuca      480

acuuaucgag uaucccagag aacgagguga uaucuagugc ggaguugcgc uuauuccgug      540

agcagguuga ccaagggccg gacugggagc gcggcuucca ccgaaucaac aucuacgagg      600

ugaugaagcc gccggcggag guaguacccg gucacuuaau cacucgucuc uuagacacgc      660

gauuaguaca ccacaacgua acgagguggg agacguucga cgucaguccg gcgguauuga      720

gguggacgcg cgagaagcag cccaacuacg gauuagcgau cgaggucacg caccuacacc      780

agacccguac gcaccagggc cagcacgucc gaauaucgcg aucgcuaccg cagggaucgg      840

guaacugggc gcaauuaaga ccguuguuag uaacguucgg ccacgacggg cgaggccacg      900

cuuuaacgcg ucgacgacgu gcgaagcgcu cgccgaagca ccacucgcag cgagcgcgaa      960

agaagaacaa gaacugccga cgucacaguc uuuacguuga cuucucggac gucggaugga     1020

acgacuggau aguugcgccg ccgggcuacc aggcguucua cugccacggg gacugcccgu     1080

ucccguuagc cgaccacuua aacaguacca accacgccau cguccagacg cuuguaaacu     1140

cgguaaacag uucaauaccc aaggcgugcu gcguacccac ggaguuaagu gcgaucucga     1200

uguuauacuu ggacgaguac gacaagguug uuuuaaagaa cuaccaggag augguugugg     1260

agggcugcgg augccguuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  5688
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt10)

<400>  5688
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gcuuaggcag acgcgcccaa ugguuauguu gguggugggg cuuauuaugu ucguguugug      120

gcccgccccc cuuaagaccc ccgcucccgg ccgcggccgc ggcggcggcg ggcggccaau      180

uauuaggcga ugggggcucg ccggggagga ccgaacaacc cccccccagc ccccaaagua      240

guagcggguu uuuauauaga agauugaaaa cccaagaaaa aagagaaaug caaaaagaaa      300

uacucagcgu cuuaggcuug ccccauagac cgagaccguu acauggguug cagcaacccc      360

aaccgcccgc cuugagacaa caagaagaac aacaacaaca acaacaauua ccgagggggg      420

aaccgccgcc gggcagguua aaaagugccc cguuguuuau guuagacuua uauaaugcgu      480

uaagugcgga uaaugaugaa gauggcgcca gcgaaggcga acgccaacaa aguuggccgc      540

augaggccgc gucgagcagu caaaggagac aacccccgcc cggggcggcc caucccuuga      600

auaggaaauc guuguuagcg ccggggagcg ggucgggggg ggccaguccg uuaacgucgg      660

cccaagauuc ggcguuuuug aaugaugccg auauggugau gucguucguc aauuuagucg      720

aauaugauaa agaauuuagu ccgaggcaaa ggcaucauaa ggaauuuaaa uuuaaucuca      780

gucaaauccc ggaaggggaa gucgucaccg ccgccgaguu uaggauauau aaagauugcg      840

ucaugggcuc guucaagaau cagaccuucu ugauaucgau cuaccaggug cuccaagaac      900

accaacaucg cgauagcgau uuauuccucc ucgauacgag ggucgucugg gcgagcgagg      960

aggggugguu agaguucgau auaaccgcga ccucgaacuu augggucguc accccgcaac     1020

acaauauggg cuugcaauua ucggucguca cccgcgacgg ggugcaugug cauccgaggg     1080

cggccggguu agucgggcgc gaugggccgu augauaaaca accguuuaug gucgccuuuu     1140

uuaaggucuc ggaaguccau gucaggacga cgcgcagcgc gaguucgaga aggaggcagc     1200

aaucgaggaa caggagcacg caaagucaag augucgccag agugaguucg gccagcgacu     1260

auaauucguc ggagcucaag accgcguguc gcaaacacga auuauacguc ucguuucagg     1320

auuuagggug gcaagauugg auaaucgccc cgaaagggua cgccgcgaac uauugcgacg     1380

gggaguguag uuuuccguug aaugcccaua ugaacgccac gaaucaugcc aucguccaaa     1440

cgcucgucca uuugaugaau ccggaauacg ugccgaagcc cuguugcgcc ccgaccaaau     1500

ugaacgcgau aagcgucuug uauuucgacg auaauaguaa cgugaucuua aagaaguauc     1560

gcaacauggu cguccgcgcc ugcggguguc auugaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  5689
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt10)

<400>  5689
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

uaagaucguu acgagcggcg gcuccgcaca guuucguagc guugugggcc ccguuauucu      120

uauugcgauc ggcguuagcg gacuucaguu uagacaacga gguacacucg aguuucauac      180

accgaagauu gcgcucgcag gagaggcgcg agaugcagcg agagauauua aguauauuag      240

gguugccgca ccgacccagg ccccacuugc aggggaagca caacucggcu ccaauguuca      300

uguuagacuu auacaacgcg auggcgguag aggagggggg gggucccggg ggucagggcu      360

ucaguuaccc cuacaaggcg guauucucua cgcagggucc gccguuagcg aguuuacagg      420

acucgcacuu cuugacggac gcggacaugg uaaugaguuu cguaaacuua guagagcacg      480

acaaggaguu cuuccacccg cgauaccacc acagggaguu ccgauucgac uuaucgaaga      540

uacccgaggg ggaggcggua acggcggcgg aguucaggau auacaaggac uacauccgag      600

agagauucga caacgagacg uuccgaauaa guguauacca gguauugcag gagcacuuag      660

guagggaguc ggacuuauuc uuguuagaca gucgcacguu augggcgucg gaggaggguu      720

gguuggucuu cgacauaacg gcgacgagua accacugggu cguaaacccc aggcacaacu      780

uagguuuaca guugucggua gagacauuag acggucaguc gauaaacccg aaguuagccg      840

gguugaucgg ucgacacggc ccgcagaaca agcagccguu caugguagcc uucuucaagg      900

cgacggaggu acacuucagg aguauaaggu cgacggguag uaagcagcga ucgcagaaca      960

ggaguaagac accaaagaac caggaggcgu uaagaauggc gaacguagcu gagaacucga     1020

guucggacca gaggcaggcg ugcaagaagc acgaguuaua cguaaguuuc cgcgacuugg     1080

gguggcagga cuggauaaua gcgccggagg gguacgcagc guacuacugc gagggugagu     1140

gcgcguuccc cuuaaacucg uacaugaacg cgacgaacca cgcgauagua cagacguuag     1200

uacacuucau caacccggag acaguaccga agccgugcug cgcgccgacg caguugaacg     1260

cgauaagugu auuauacuuc gacgacucga guaacguaau cuuaaagaag uacaggaaca     1320

ugguaguacg agcgugcggu ugccacugag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  5690
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt10)

<400>  5690
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagg       60

cgucggccgc guuacuaugc uuauuacuua ccgccgcggc guucucgccg cagggcuuag      120

cgcaaccggu agguauaaac accaguacga caugcugcua cagguucaua aacaagaaga      180

ucccgaagca gcgauuagag aguuaccguc guacgacgag cucucacugc ccgcgugagg      240

cggucauauu caaaacgaag uuagacaagg agauaugcgc agaccccacc cagaaguggg      300

uacaggacuu caugaagcac uuagacaaga agacgcagac gccuaaguug ugaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  5691
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt10)

<400>  5691
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguuau       60

ugaccuugau aaucuuacuc ccggucguca gcaaguucuc guucgucucg uugagcgccc      120

cccaacauug gucgugcccg gaggggaccu uggccgggaa cggcaacagu accugcgucg      180

ggccggcccc guuucucauc uuuagucacg ggaacucgau auuccgcauc gauaccgagg      240

ggacgaacua cgaacagcuc gucgucgacg ccggggugag cgucauaaug gacuuccacu      300

acaacgaaaa gcgcauauac ugggucgacc ucgagcgcca guugcuccag cgcgucuucu      360

uaaacggcag ccgccaggaa cgcgucugca acaucgaaaa gaacgucagc gggauggcca      420

ucaacuggau caacgaggag gucaucugga gcaaccagca agaggggaua aucaccguca      480

ccgacaugaa ggggaacaac agucauaucu ugcucucggc ccucaaguac ccggccaacg      540

ucgccgucga cccggucgag cgcuucaucu ucuggagcag cgaagucgcc gggucguugu      600

accgcgccga cuuggacggg gucgggguca aagccuuacu cgaaaccagc gaaaagauca      660

ccgccgucag ccucgacguc uuggacaaaa gauuauucug gauccaauau aaucgcgagg      720

ggucgaacag cuugaucugu aguugcgacu acgacggggg gagcgugcau aucucgaagc      780

acccgaccca acacaaccuc uucgccauga guuuguucgg ggauaggaua uuuuacagca      840

ccuggaagau gaaaaccauc uggaucgcga auaagcauac cgggaaagau augguccgca      900

ucaauuugca cagcagcuuc gucccguugg gggaguuaaa ggucguccac ccguuggccc      960

agccgaaagc cgaggacgau accugggaac cggaacaaaa guuguguaag cuccgcaagg     1020

ggaauuguuc gucgaccguc ugcggccagg auuugcaaag ccaucucugu augugcgccg     1080

aaggguaugc guugucgagg gauagaaaau auugcgagga cgucaacgag ugcgccuucu     1140

ggaaccacgg gugcaccuug ggcugcaaga auacgccggg gaguuacuau uguaccuguc     1200

cggucggguu cgucuuauug ccggacggca agaggugcca ccaguugguc aguugcccga     1260

ggaacgucag cgaguguucg cacgauugcg ucuuaaccag cgaggggccg cucugcuuuu     1320

gcccggaggg gagcgucuug gaacgcgacg gcaagaccug cucggggugc aguagcccgg     1380

acaacggggg gugcucgcaa uugugugucc cguugucgcc ggucaguugg gagugcgacu     1440

guuucccggg cuacgauuug caguuagacg agaagucgug cgccgccagc gggccgcagc     1500

cguuccucuu auucgcgaac agccaggaca ucaggcauau gcacuucgac gggaccgauu     1560

acgggaccuu auugucgcaa caaaugggga uggucuacgc guuggaccac gauccggucg     1620

agaacaaaau cuauuucgcg cacaccgcgu uaaaauggau cgaacgcgcc aacauggacg     1680

ggagucaaag ggagcgcuug aucgaagagg gggucgacgu cccggagggg uuggccgucg     1740

auuggaucgg gaggcgcuuu uacuggaccg aucgcggcaa gagcuuaauc gggcgcucgg     1800

accucaacgg caagaggagu aagaucauaa ccaaagaaaa uauaagccag ccgaggggga     1860

ucgccgucca cccgauggcg aaacgccucu uuuggaccga caccggcauc aacccgagga     1920

ucgagucgag caguuugcag ggguugggga gguuagucau cgcgucgagc gacuugauau     1980

ggccgucggg gaucaccauc gauuuucuca ccgauaaacu cuauuggugu gacgcgaaac     2040

aaagcgucau cgagauggcg aacuuagacg ggagcaagag gaggcgcuug acgcaaaacg     2100

acgucgggca uccguucgcc gucgccgucu ucgaagacua cgucugguuu agcgacuggg     2160

ccaugccgag cgucaugcgc gucaauaaac gcaccgggaa ggaccgcguc agguugcagg     2220

ggucgauguu aaaaccgagc agcuuagucg ucguccaccc gcucgccaag ccgggggccg     2280

acccgugucu cuaccagaau ggggggugcg agcacaucug uaagaaacgc uuggggaccg     2340

ccuggugcag cugcagggag ggguucauga aggcgagcga cggcaagacc ugcuuagccu     2400

uagacgggca ccaauuacuc gccggggggg aggucgacuu gaaaaaucag gucaccccgc     2460

ucgauauacu caguaaaacc cgcgucagcg aggacaauau caccgagagc cagcauaugu     2520

uggucgccga gauaaugguc agcgaccagg acgauugcgc cccggucggg uguucgaugu     2580

acgccagaug caucagcgaa ggggaagacg cgaccugcca augccucaag ggguucgccg     2640

gcgacgggaa guugugcagc gacaucgacg agugcgaaau gggggugccg gucuguccgc     2700

cggcgaguag uaaauguaua aauacggagg ggggguacgu guguagaugu agcgaggggu     2760

aucaggggga cggcauccau ugcuuggaca ucgacgaaug ucaguuaggc gaacauucgu     2820

gcggggaaaa cgcgucgugu accaacaccg aaggggggua cacguguaug ugcgccggga     2880

gguuaagcga gccgggguua aucuguccgg auagcacccc gccgccgcau uugcgcgagg     2940

acgaucauca uuacaguguc cgcaacucgg auagcgagug cccguuaagu caugacggcu     3000

auuguuugca cgacgggguc uguauguaca ucgaggcccu cgauaaauac gccuguaauu     3060

gcgucgucgg guauauaggc gaaaggugcc aauauaggga uuuaaaaugg ugggaguuaa     3120

ggcaugccgg gcauggccaa caacaaaaag ugauagucgu cgccgugugu gucgucgucu     3180

uggugauguu auuguuguua ucguuauggg gcgcgcauua uuaucgcacc caaaaauuau     3240

ugagcaagaa uccgaaaaac ccguacgaag aaagcucgcg cgacguccgc ucgaggcgcc     3300

cggccgauac cgaagacggc augaguagcu guccgcagcc gugguucguc gucaucaagg     3360

agcaucagga uuugaaaaac ggcgggcagc cggucgccgg ggaagacggg caagccgccg     3420

acggcagcau gcagccgacc agcuggcgcc aagaaccgca acucugcggg auggggaccg     3480

aacaggggug uuggaucccg gucaguucgg acaaagggag uugcccgcaa gucauggaaa     3540

ggucguucca caugccgagu uacggcaccc aaacguugga gggcggggug gaaaaaccgc     3600

acagcuuguu gagcgccaau ccgcucuggc agcagcgcgc guuagauccg ccgcaucaga     3660

uggaauuaac ccaaugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  5692
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt10)

<400>  5692
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugacgg       60

ccggccgccg cauggaaaug uugugcgcgg ggcgcgugcc ggccuuauua uuguguuuag      120

gguuucacuu guugcaagcc guguugucga ccaccgucau cccgagcugc auaccggggg      180

aaaguucgga caauuguacc gcccucgucc aaaccgagga uaacccgagg gucgcccagg      240

ucagcaucac caaaugcucg agcgauauga acggguacug ccuccacggg caauguauau      300

acuuagucga uaugucgcag aauuauuguc gcugcgaggu cggguacacc ggggugaggu      360

gcgagcauuu uuuccucacg gugcaucagc cgcucucgaa ggaguacguc gcccucacgg      420

ucaucuugau cauccucuuc uugauaaccg ugguggggag uaccuacuac uuuugucgcu      480

gguaucgcaa caggaagucg aaggagccga aaaaagagua cgaacgcguc acgagcggcg      540

acccggaacu cccccaggug ugaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  5693
<211>  850
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt10)

<400>  5693
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcgg       60

agggugagau aacgacguuc acugcguuaa cggagaaguu caacuuaccg ccggguaacu      120

acaagaagcc caaguuguua uacugcucga acggggggca cuucuuacga auauuaccag      180

acggcacggu agacgguacc cgagaccggu cggaccagca cauccaguua caauuaucgg      240

cggagagugu uggcgaggua uacaucaagu cgacugagac agggcaguac uuggcgaugg      300

acacggacgg guuauuguac gggagucaaa cgccgaacga ggagugcuua uucuuagagc      360

gcuuggagga gaaccacuac aacacguaca ucucgaagaa gcacgcggag aagaacuggu      420

ucguaggguu aaagaagaac gguaguugca agcgggggcc acgcacgcac uacggucaga      480

aggcgaucuu auucuugccg uuaccaguau cgagugacug aggacuagug caucacauuu      540

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      600

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      660

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      720

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc      840

caccagaauu                                                             850


<210>  5694
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt10)

<400>  5694
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

gcgucggggg cggggacgug gaggacguga ccccgcgccc gggcgggugc cagaucucgg      120

gccggggcgc ccgcgggugc aacggcaucc ccggggccgc ggccugggag gccgcccugc      180

cccggcgccg gccccgccgg cacccguccg ucaacccccg cucgcgggcc gcgggcucgc      240

cccgcacccg ggggcgccgg acggaggagc gccccuccgg cucccggcuc ggcgaccgcg      300

ggcggggccg cgcccugccc gggggccggc ugggcgggcg cggccggggg cgcgcccccg      360

agcgcguggg cgggcggggc cgcggccggg ggaccgccgc gccccgcgcc gcccccgccg      420

cccggggcuc gcgcccgggg cccgcgggca ccauggccgc cggguccauc accacgcucc      480

ccgcccugcc cgaggacggc ggcucggggg ccuucccgcc cggccacuuc aaggacccca      540

agcggcugua cugcaagaac gggggcuucu uccuccgcau ccaccccgac gggcgggugg      600

acggcguccg cgagaagucc gacccgcaca ucaagcugca gcugcaggcg gaggagcggg      660

gcgugguguc gaucaagggg gucugcgcca accgcuaccu cgccaugaag gaggacggcc      720

ggcugcuggc cuccaagugc gugaccgacg agugcuucuu cuucgagcgc cucgagucga      780

acaacuacaa caccuaccgg ucccgcaagu acaccucgug guacguggcc uuaaagcgga      840

cggggcagua caaguuaggc uccaagaccg gccccgggca gaaggcgauc cucuucuuac      900

ccaugucggc caaguccuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  5695
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt10)

<400>  5695
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aguggauauu aacguggaua uugccgacgu uauuauacag gucgugcuuc cacauaauau      120

gcuuggucgg gacaauaagu uuagcgugca acgacaugac gcccgagcaa auggcgacga      180

acguaaauug cucgaguccg gagagacaca cgaggucgua ugacuauaug gaggggggcg      240

acauaagagu caggagauua uucugcagga cacaauggua uuugagaaua gacaagaggg      300

gcaaagucaa ggggacgcaa gagaugaaaa acaacuauaa cauaauggag auaagaacgg      360

uagccgucgg cauagucgcg auaaaagggg uagagaguga guucuauuua gcgaugaaca      420

aggaggggaa guuauaugcg aagaaggagu gcaacgagga cugcaauuuc aaggaguuga      480

uauuagagaa ccacuauaac acguacgcgu cggccaagug gacacacaac ggcggggaga      540

uguucgucgc guuaaaccaa aagggcauac cggucagggg gaagaagacg aagaaagagc      600

aaaagacggc gcacuucuug ccgauggcga uaacgugagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  5696
<211>  1009
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt10)

<400>  5696
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagu       60

uguuacccuc aguuguacuc aaauuauucu uagcggccgu auuaagugcu cuugugaccg      120

gcgagucguu ggagcguuug cgccgcgguc uugcagcggg cacgaguaac ccggacccgc      180

cgacggucuc gaccgaccag uuacucccuc ucgggggcgg gcgcgaccgu aagguucggg      240

accuccagga ggcggacuua gaccuccuac guguuacgcu uucgucgaag ccccaggccu      300

uggcgacccc uaacaaggag gagcacggua agcguaagaa gaaggggaag gggcuuggca      360

agaagcguga cccgugcuug cgaaaguaca aggacuucug cauacacggg gagugcaagu      420

acgucaagga guuacgagcg ccgaguugca ucugccaccc gggcuaccac ggggagcgau      480

gccacggcuu gucguuaccg guagagaacc guuuguacac uuacgaccac acuaccauac      540

ucgccguagu cgcgguuguc uuaucgucgg uaugcuuauu aguaauagua ggcuuauuaa      600

uguuccgaua ccaccgacgc gggggcuacg acguagagaa cgaggagaag gugaagcuag      660

ggaugacgaa cucgcacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      720

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      780

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      840

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      960

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1009


<210>  5697
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt10)

<400>  5697
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ucacgaaguu guuaccggcg uuauuauuac aacacguguu guuacacuug uuguuauugc      120

cgauagcgau accguaugcc gaagggcagc gcaagcgccg caauaccauc cacgaguuua      180

agaagagugc caaaaccacg uugauaaaga ucgacccggc cuuaaaaauc aagacgaaaa      240

aggucaacac cgccgaucag ugcgccaacc gcugcacccg caacaagggg uugccguuua      300

ccuguaaagc cuucgucuuc gacaaggccc gcaagcaaug uuugugguuu ccguuuaacu      360

cgaugagcuc gggggucaag aaggaguucg ggcacgaguu cgauuuguau gagaauaagg      420

auuauauccg caauuguaua aucgggaaag ggaggucgua uaaagggacc gucagcauaa      480

ccaaaucggg gauaaaaugc caaccguggu cgaguaugau cccgcaugag cauucguucc      540

ucccgagcuc guacagaggg aaggauuugc aagagaauua uugcaggaac ccgaggggcg      600

aggagggcgg gccguggugc uuuaccucga acccggaagu cagguaugag gugugcgaua      660

ucccgcaaug cagcgagguc gaguguauga cguguaacgg cgaaucguac aggggguuga      720

uggaccacac cgagagcggg aaaaucugcc aaagguggga ccaccaaacc ccgcauagac      780

auaaauuucu cccggagcgc uauccggaua aaggguucga cgacaacuac uguaggaacc      840

cggacgggca accccgcccg ugguguuaua ccuuggaucc gcauacgagg ugggaauauu      900

gcgccaucaa aaccugugcc gauaacacca ugaacgauac cgacgucccg cucgagacca      960

ccgaguguau acaggggcag ggggaggggu aucgcgggac cgugaacacg aucuggaacg     1020

ggaucccgug ccaaaggugg gacagccaau auccgcauga acacgauaug accccggaga     1080

acuuuaaaug uaaagauuug agggagaacu auuguaggaa cccggacggc agcgagagcc     1140

cguggugcuu cacgaccgac ccgaauauaa gggucgggua uuguagucag aucccgaauu     1200

gcgacaugag ccacgggcaa gacugcuaua ggggcaacgg gaaaaacuac auggggaauc     1260

ucagucagac ccgcagcggg uugaccugca gcauguggga uaaaaauaug gaggaucucc     1320

acaggcacau auuuugggag ccggacgccu cgaaauuaaa cgaaaacuau uguaggaacc     1380

cggacgacga cgcccacggg ccgugguguu auaccgggaa cccguugauc ccgugggacu     1440

auuguccgau caguaggugc gagggggaca cgaccccgac caucgugaac cucgaucacc     1500

cggucaucag cugcgcgaag accaagcagc ucagggucgu caacggcauc ccgaccagga     1560

ccaauaucgg guggaugguc ucgcuccgcu aucgcaacaa gcacauaugu ggggggagcc     1620

ucaucaaaga aucguggguc uugaccgcca ggcaaugcuu uccgagcagg gaucucaagg     1680

acuacgaggc cugguugggg auccacgacg ugcaugggcg cggggacgaa aaguguaagc     1740

aagucuugaa cgucagucaa uuagucuacg ggccggaggg gagcgacuua guccucauga     1800

aauuggcgcg cccggccgug uuagacgacu ucgucucgac caucgaccuc ccgaauuacg     1860

gguguaccau cccggagaaa acgucguguu cggucuaugg guggggguau accgggcuca     1920

uaaauuacga cggguugcuc agggucgccc acuuguauau cauggggaac gaaaaguguu     1980

cgcaacacca caggggcaaa gucaccuuaa acgaaagcga gaucugcgcc ggcgccgaga     2040

aaaucgggag cgggccgugc gaaggcgacu auggggggcc guuggucugc gaacagcaca     2100

aaaugcgcau ggucuugggg gugaucgucc cggggagggg gugcgcgauc ccgaacaggc     2160

cggggaucuu cgugaggguc gccuacuacg ccaaguggau ccauaagauc auccucaccu     2220

auaaaguccc gcaaagcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  5698
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt10)

<400>  5698
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcga       60

aggcggcggc aauagggaua gacuuaggua cgacguacuc gugcguuggu guauuccagc      120

acgguaaggu agagauaaua gcgaacgacc aggguaaccg gacgacgccg aguuacgucg      180

cguucaccga cacggagcgc uugaucgggg acgccgcgaa gaaccaggua gcuuuaaacc      240

cacaaaacac gguuuucgac gcaaagcgac ucauagggcg aaaguucggg gaccccgucg      300

uacaaucaga caugaagcac uggccguucc aggucauaaa cgacggugac aagccgaagg      360

uccagguaag uuacaagggc gagacgaagg cguucuaccc ugaggagauc ucaaguaugg      420

uauugacgaa gaugaaggag auagcggagg cauacuuagg auaccccgug acgaacgccg      480

uaaucacggu ccccgcguac uucaacgacu cucagcggca ggcgacgaag gacgcaggcg      540

uaaucgcagg guuaaacgua uugcgcauca uaaacgagcc gaccgcggcg gcgauagcau      600

acggguuaga ccggaccggg aagggugagc gaaacguauu aaucuucgac uugggugggg      660

guacguucga cgucucgaua uuaaccaucg acgacggcau auucgaggua aaggcgaccg      720

ccggggacac gcacuuaggc ggggaggacu ucgacaaccg auuggucaac cacuucguag      780

aggaguucaa gcgaaagcac aagaaggaca uaucgcagaa caagcgugcg guaagaaggu      840

uacgaacggc gugcgagcgg gcuaagcgca cguuaaguuc gaguacgcag gcgucguugg      900

agauagacag uuuauucgag gguauagacu ucuacacuuc gauaacgcgu gcacgauucg      960

aggaguuaug cucggacuua uucaggucga cguuagagcc gguagagaag gcauuacgag     1020

acgcgaaguu ggacaaggca cagauacacg acuuaguauu aguagguggu ucgacgcgga     1080

uaccgaaggu acagaaguug uuacaggacu ucuucaacgg ucgagacuua aacaagucga     1140

ucaacccgga cgaggcggua gcguacgggg ccgcgguaca ggccgcgaua uugaugggug     1200

acaagaguga gaacguacag gacuuauuau uauuagacgu agcacccuua ucuuuggguu     1260

uagagaccgc gggugggguc augacggcgu uaauaaagcg aaacucgacg aucccgacga     1320

agcagaccca gaucuucacu acguacucgg acaaccagcc ggguguauug auccagguau     1380

acgaggguga gcgagcgaug accaaggaca acaacuuauu aggacguuuc gaguugucgg     1440

guauaccgcc cgcaccucga ggggucccgc agaucgaggu cacguucgac aucgacgcga     1500

acgguaucuu aaacguaacg gcgaccgaca aaaguacggg gaaggccaac aagaucacga     1560

uaacgaacga caagggucga uuaucgaagg aggagauaga gaggaugguc caggaggcag     1620

agaaguacaa ggccgaggac gagguccaga gagagcgagu aagugcgaag aacgcguugg     1680

agucguacgc guucaacaug aagagugcgg ucgaggacga ggguuuaaag gguaagaucu     1740

cggaggccga caagaagaag gucuuagaca agugccagga gguuauaucu ugguuagacg     1800

cgaacacguu agcggagaag gacgaguucg agcacaagcg caaggaguua gagcagguau     1860

gcaacccgau aauaucgggu uuguaccagg gggcgggcgg gccggguccg ggugguuucg     1920

gcgcgcaggg accgaagggu gguagugggu cggguccgac gaucgaggag guagacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  5699
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt10)

<400>  5699
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcga       60

aggcggcggc aauagggaua gacuuaggua cgacguacuc gugcguuggu guauuccagc      120

acgguaaggu agagauaaua gcgaacgacc aggguaaccg gacgacgccg aguuacgucg      180

cguucaccga cacggagcgc uugaucgggg acgccgcgaa gaaccaggua gcuuuaaacc      240

cacaaaacac gguuuucgac gcaaagcgac ucauagggcg aaaguucggg gaccccgucg      300

uacaaucaga caugaagcac uggccguucc aggucauaaa cgacggugac aagccgaagg      360

uccagguaag uuacaagggc gagacgaagg cguucuaccc ugaggagauc ucaaguaugg      420

uauugacgaa gaugaaggag auagcggagg cauacuuagg auaccccgug acgaacgccg      480

uaaucacggu ccccgcguac uucaacgacu cucagcggca ggcgacgaag gacgcaggcg      540

uaaucgcagg guuaaacgua uugcgcauca uaaacgagcc gaccgcggcg gcgauagcau      600

acggguuaga ccggaccggg aagggugagc gaaacguauu aaucuucgac uugggugggg      660

guacguucga cgucucgaua uuaaccaucg acgacggcau auucgaggua aaggcgaccg      720

ccggggacac gcacuuaggc ggggaggacu ucgacaaccg auuggucaac cacuucguag      780

aggaguucaa gcgaaagcac aagaaggaca uaucgcagaa caagcgugcg guaagaaggu      840

uacgaacggc gugcgagcgg gcuaagcgca cguuaaguuc gaguacgcag gcgucguugg      900

agauagacag uuuauucgag gguauagacu ucuacacuuc gauaacgcgu gcacgauucg      960

aggaguuaug cucggacuua uucaggucga cguuagagcc gguagagaag gcauuacgag     1020

acgcgaaguu ggacaaggca cagauacacg acuuaguauu aguagguggu ucgacgcgga     1080

uaccgaaggu acagaaguug uuacaggacu ucuucaacgg ucgagacuua aacaagucga     1140

ucaacccgga cgaggcggua gcguacgggg ccgcgguaca ggccgcgaua uugaugggug     1200

acaagaguga gaacguacag gacuuauuau uauuagacgu agcacccuua ucuuuggguu     1260

uagagaccgc gggugggguc augacggcgu uaauaaagcg aaacucgacg aucccgacga     1320

agcagaccca gaucuucacu acguacucgg acaaccagcc ggguguauug auccagguau     1380

acgaggguga gcgagcgaug accaaggaca acaacuuauu aggacguuuc gaguugucgg     1440

guauaccgcc cgcaccucga ggggucccgc agaucgaggu cacguucgac aucgacgcga     1500

acgguaucuu aaacguaacg gcgaccgaca aaaguacggg gaaggccaac aagaucacga     1560

uaacgaacga caagggucga uuaucgaagg aggagauaga gaggaugguc caggaggcag     1620

agaaguacaa ggccgaggac gagguccaga gagagcgagu aagugcgaag aacgcguugg     1680

agucguacgc guucaacaug aagagugcgg ucgaggacga ggguuuaaag gguaagaucu     1740

cggaggccga caagaagaag gucuuagaca agugccagga gguuauaucu ugguuagacg     1800

cgaacacguu agcggagaag gacgaguucg agcacaagcg caaggaguua gagcagguau     1860

gcaacccgau aauaucgggu uuguaccagg gggcgggcgg gccggguccg ggugguuucg     1920

gcgcgcaggg accgaagggu gguagugggu cggguccgac gaucgaggag guagacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  5700
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt10)

<400>  5700
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcga       60

cggcgaaggg uauagcuaua gguauagacu uaggaacgac auacucgugc guaggugucu      120

uccagcacgg gaaggucgag aucauagcua acgaccaggg gaacaggaca acgccgaguu      180

acgucgcguu caccgacacu gagagauuga ucggugacgc ggcgaagaac caggucgcga      240

ugaacccuca aaacacggua uucgacgcga agcgguuaau cggucgcaag uucaacgacc      300

cggucguuca ggcggacaug aaguuauggc cguuccaagu aauaaacgag ggcggaaagc      360

cgaagguauu gguaucguac aagggugaga acaaggcauu cuacccggaa gagauaaguu      420

cgaugguuuu aaccaaguua aaggagacag cggaggcguu cuuaggucau ccgguaacua      480

acgcgguaau cacgguaccc gcuuacuuca acgacaguca gcggcaggcg acgaaggacg      540

cgggggucau agcggguuua aacguauuac gcauaauaaa cgagccaacg gcagcggcga      600

uagcguacgg ucuugacaag gggggacagg gugagcggca cguauuaauc uucgacuuag      660

guggcgguac auucgacguc ucgauauuga cgaucgacga cgguauauuc gagguaaagg      720

cgacggcggg ugacacgcac uuagguggug aggacuucga caacagauua guaagucacu      780

ucgucgagga guucaagcgg aagcacaaga aggacauauc gcaaaacaag cgcgcuguaa      840

ggagauugcg gacggccugc gagcgcgcga agcggacguu aaguucgucg acgcaggcga      900

accucgagau agacucguug uacgagggua uagacuuuua cacgaguauc acgcgagcga      960

gauucgagga guuaugcgcc gacuuauucc gcgggacauu ggagcccguu gagaaggcgu     1020

uaagggacgc gaagauggac aaggcgaaga uccacgacau aguauuaguc ggugguucga     1080

cccgaauacc gaagguacag cgguuauuac aagacuacuu caacggucgc gacuugaaca     1140

agucgauaaa cccggacgag gcgguagcgu acggggcggc aguccaggcg gcgauauuaa     1200

ugggggacaa gucggagaag guccaagacu uauuauuguu ggacguugcg ccguuaaguu     1260

uagguuuaga gacugcgggc gguguaauga cggcguuaau caagcggaac ucgacaauac     1320

caacgaagca gacgcaaaua uucacuacgu acagugacaa ccagccgggu guauugauac     1380

agguauacga gggugagcgg gcgaugacga aggacaacaa cuuauuaggu cguuucgacu     1440

uaacugguau accuccggcu ccgcgggggg uaccgcaaau agaggucacg uucgacauag     1500

acgcgaacgg gaucuuaaac guaacggcga ccgacaaguc gacagguaag guuaacaaga     1560

uaacuauaac gaacgacaag gguagauuau cgaaggagga gaucgagagg auggucuugg     1620

acgcggagaa guacaaggca gaggacgagg uacagagaga aaagauagcg gcgaagaacg     1680

cguuagagag uuacgcguuc aacaugaagu cgguaguauc ggacgaggga uuaaagggua     1740

agaucucgga gagugacaag aacaagauau uagacaagug caacgaguua uuaucguggu     1800

uggagguuaa ccaguuagcg gagaaggacg aguucgacca uaagaggaag gaguuagagc     1860

aaaugugcaa cccgaucauc acgaaguuau accagggggg uugcacgggu ccggcgugcg     1920

guacggguua cgucccuggg cgaccggcaa cagguccgac gauagaggag guagacugag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  5701
<211>  2302
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt10)

<400>  5701
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucgg       60

ccagggggcc ggccauaggg aucgauuugg ggacgacgua uagcuguguc ggggucuuuc      120

aacaugggaa gguggagauc auagccaaug aucagggcaa ucgcacgacc ccgaguuacg      180

ucgcguucac cgauacggag agguugauag gggaugccgc gaaaaaucaa gucgccauga      240

auccgaccaa uaccauauuu gaugccaaac gcuugauagg gaggaaauuu gaggaugcca      300

ccgugcaguc ggauaugaaa cauuggccgu uuagggucgu cagugagggg gggaagccga      360

aaguacaggu ggaguauaag ggggaaacca aaacguucuu uccggaggaa auaagcucga      420

uggucuugac gaagaugaag gagaucgccg aagccuacuu gggggggaaa gugcauucgg      480

ccgucaucac cgugccggcc uauuucaaug auucgcagcg ccaggccacc aaggaugccg      540

ggacgaucac cggguugaau guguugagga ucauaaacga gccgaccgcc gccgccauag      600

ccuauggguu ggauaaaaag gggugugcgg ggggggaaaa gaauguguug aucuuugauu      660

uggggggcgg gaccuuugau gugagcaucu ugacgaucga ggaugggaua uuugaaguga      720

agucgaccgc gggggauacc cauuuggggg gcgaggauuu ugauaauagg auggucucgc      780

acuuggcgga ggaauuuaag cgcaaacaua aaaaggacau cgggccgaau aagagagccg      840

uccgccgcuu gcgcacggcc ugugagagag ccaagcgcac guugucgagc ucgacccagg      900

ccucgaucga gauagauagu uuguaugagg gcgucgauuu uuauacgagc auaaccagag      960

cgagguucga agaguugaau gcggacuuau uuagggggac cuuggagccg guggagaagg     1020

ccuugaggga ugccaagcuc gauaaggggc agauccagga gaucguguua guggggggga     1080

guacgaggau accgaagaua cagaaguugu ugcaggauuu uuuuaauggc aaggaguuga     1140

auaagagcau caauccggac gaggccgugg cguauggggc cgccguccag gccgccaucu     1200

ugauaggcga uaagucggaa aaugugcagg auuuguuguu auuggauguc acgccguuga     1260

gcuugggcau cgaaaccgcc ggggggguca ugacgccguu aaucaagagg aauaccacga     1320

ucccgaccaa gcaaacgcaa acguuuacca cguauucgga uaaucaaagc agugucuugg     1380

ugcaagucua ugaaggggag agggccauga ccaaggauaa uaauuugcuc gggaaauuug     1440

auuugaccgg gauccccccg gccccgaggg gggucccgca gauagaggug accuucgaua     1500

ucgaugcgaa ugggauauug aaugucacgg ccgcggauaa gucgaccggc aaagagaaua     1560

aaauaaccau caccaaugau aagggccgcu uaucgaagga ugauaucgau aggauggugc     1620

aggaggccga gagguauaag agcgaggacg aagccaaucg cgauagggug gccgccaaaa     1680

augccuuaga gagcuauacg uauaauauaa aacaaacggu ggaggaugag aaguuaaggg     1740

ggaagaucuc ggagcaggau aagaauaaga ucuuagauaa gugccaggag gugaucaauu     1800

gguuggauag gaaucagaug gcggagaagg augaguauga gcauaagcag aaggaguugg     1860

agagggucug uaauccgauc auaagcaagc ucuaucaggg ggggccgggg gggggcucgg     1920

gggggggggg gaguggggcc ucgggggggc cgacgauaga ggaggucgac ugaggacuag     1980

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2040

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2100

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2160

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2280

ucuuuucaga gccaccagaa uu                                              2302


<210>  5702
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt10)

<400>  5702
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucag       60

ucguagguau cgaccucggu uuucaaaguu guuacguagc gguagcgcga gcuggaggua      120

uagagacgau agcaaacgaa uacucggacc gaugcacucc ugcgugcaua ucguucgggc      180

cgaagaacag gucgauaggg gccgcggcaa agucgcaggu uaucucaaac gcgaaaaaca      240

cgguacaggg uuucaagcga uuucacgguc gugcguucuc ggacccuuuc gucgaggccg      300

agaagaguaa cuuagcguac gacauaguuc aauuaccgac gggucucacg ggcauuaagg      360

uaacuuacau ggaagaggag cgcaacuuca cuacggagca gguaacggcg auguuguuau      420

cgaaguuaaa ggaaacggca gagucgguau uaaagaagcc agugguagac ugcguaguau      480

caguaccgug cuucuacacg gacgcggagc ggcguucggu uauggacgcc acgcagauag      540

cggggcucaa cuguuuacgc cuaaugaacg agacgacggc cguagcguua gcguacggga      600

uuuacaagca ggacuugcca gcgcuugagg agaagccgcg caacguugua uucguggaca      660

ugggacacuc ggcauaccag gugucggucu gcgcguucaa ccgggggaag cucaaggucu      720

uagcgacggc guucgacacc acguuaggcg gacgcaaguu cgacgaggua cucguuaacc      780

acuucugcga ggaguucggu aagaaguaua aguuagacau aaagucgaag auucgagcgu      840

ugcuucguuu aucgcaggag ugcgagaagu uaaagaaguu aaugucagcg aacgcgucgg      900

acuugccccu uucgaucgag ugcuucauga acgacguaga cguuucaggg accaugaaca      960

gggggaaguu cuuagagaug uguaacgacu uauuggcacg agucgaaccu cccuugaggu     1020

cggucuuaga gcagacaaag uugaagaagg aggacauaua cgcgguagag aucgucggag     1080

gggcaacgcg uauuccggca guuaaggaga agauaucgaa guucuucggc aaggaguuau     1140

cgacgacgcu uaacgcggac gaggcgguaa cgagggguug cgcguuacag ugcgcuauac     1200

uuucuccagc guucaaggua cgcgaguucu cgauaacgga cguuguuccg uaccccauca     1260

guuuacggug gaacucgccg gcggaggagg guucgucgga cugcgaggug uucucgaaga     1320

accacgcggc gcccuucucg aaggucuuaa cguucuaccg aaaagagccg uucacauuag     1380

aggcauacua caguucgcca caggaccuuc cuuacccgga cccggcgauc gcacaguucu     1440

cgguacaaaa gguuacgccc cagucggacg guucgucguc gaaggucaag guaaagguga     1500

ggguuaacgu ucacgguauc uuuucgguca guucggcguc gcuuguagag guccacaagu     1560

cggaggagaa cgaggagccg auggagacgg accagaacgc gaaagaggag gagaaaaugc     1620

agguagacca ggaggagccg cacguagagg agcagcaaca gcagacgccg gcggagaaca     1680

aggcggaguc ggaggagaug gagacuucgc aggcgggcuc gaaggacaag aaaauggacc     1740

agccuccgca ggcgaaaaag gcgaagguca agacaucuac cgucgacuua ccgauagaga     1800

accaguuauu guggcaaauc gaccgagaga uguuaaacuu auacaucgag aacgagggga     1860

aaaugaucau gcaggacaag uuggaaaagg agcgcaacga cgcgaaaaac gcgguugagg     1920

aguacguuua cgagaugcgu gacaaguuau cgggcgagua cgagaaguuc gucucggagg     1980

acgaccgaaa cucauucacg uuaaaguugg aggacacgga gaacugguua uacgaggacg     2040

gggaggacca accgaagcag guauacgucg acaagcuagc ggagcuuaag aacuugggac     2100

agcccauaaa gaucagguuc caagagagug aggagcgccc gaagcuauuc gaggaguuag     2160

guaagcaaau acagcaguac augaagauca uaucuaguuu uaagaacaag gaggaccaau     2220

acgaccacuu agacgcggca gacaugacua aggucgagaa gaguacgaac gaggcgaugg     2280

aguggaugaa caauaaguua aacuuacaaa acaagcaguc guuaacgaug gacccgguag     2340

uaaagucgaa ggagaucgag gccaagauca aggaguuaac cucuacaugc ucgccaauca     2400

uaucgaagcc gaagccgaag guagagccgc cgaaggagga gcagaagaac gccgagcaaa     2460

acggccccgu agacggucag ggugacaacc ccgggccuca ggcggcagaa caggggacgg     2520

acaccgcggu accgucugac ucggacaaaa aguuaccgga gauggacauc gacugaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  5703
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt10)

<400>  5703
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcg       60

ucgucgggau cgauuugggg uucuugaauu guuauauagc cguggcccgc ucggggggga      120

uagaaacgau agcgaacgaa uauucggauc gcuguacgcc cgcgugcauc agccucggga      180

gccgcaccag ggcgauaggg aacgccgcca aaucgcaaau cgugaccaau guccgcaaca      240

ccauccacgg guuuaagaaa uugcacggca ggagcuucga cgauccgauc guccagaccg      300

agcgcauacg cuugccguac gaauuacaaa agaugccgaa cgggucggcc ggggucaaag      360

ucagauaucu cgaagaggaa cgcccguucg ccaucgaaca agucaccggg auguuacucg      420

cgaaauugaa ggaaaccagc gagaacgccc ucaaaaagcc ggucgccgau ugcgucauca      480

gcaucccguc guuuuucacc gacgcggaac gccgcagcgu cauggccgcc gcgcaagucg      540

ccgggcucaa cugccuccgc cucaugaacg agaccaccgc cgucgccuua gccuacggga      600

ucuacaagca agacuugccg ccgcucgacg aaaagccgcg caacgucguc uucaucgaca      660

uggggcauag cgcguaccaa gugcucgucu gcgccuuuaa uaaagggaag uugaaggugc      720

ucgccaccac guucgacccg uaccucgggg ggcgcaauuu cgacgaagcc cucgucgauu      780

auuuuugcga cgaauuuaaa acgaaguaca aaaucaacgu caaggagaau agcagagcgc      840

uccucaggcu cuaccaagaa ugcgagaagu ugaaaaaauu gaugucggcc aacgccagcg      900

acuugccgcu caauaucgaa ugcuuuauga acgauuugga cgucagcucg aagaugaauc      960

gcgcccaguu cgaacaauua ugcgccaguu ugcucgcgcg cgucgagccg ccgcucaaag     1020

ccgucaugga gcaagccaau cuccaaaggg aggauaucuc gucgaucgag aucgucgggg     1080

gggccaccag gaucccggcc gucaaggagc aaauaaccaa guuuuucuug aaggauaucu     1140

cgacgacccu caacgccgac gaggccgucg cccgcgggug cgcccuccaa ugcgccaucu     1200

ugagcccggc cuucaagguc agggaguuca guaucaccga uuuggucccg uacagcauaa     1260

cccuccgcug gaaaacgagc uucgaggacg ggucgggcga gugcgagguc uuuugcaaaa     1320

aucauccggc gccguuuagc aaagugauca ccuuucauaa aaaagagccg uucgaguugg     1380

aggccuucua caccaaccuc caugaggucc cguauccgga cgcccgcauc ggcucguuua     1440

ccauccaaaa cgucuucccg caaagcgacg gggacucgag uaaggucaaa gucaagguca     1500

gggucaauau acacgggaua uuuucggucg ccucggccag cgucaucgaa aaacagaacc     1560

ucgaggggga ccauucggac gccccgaugg aaaccgagac cagcuucaag aacgagaaua     1620

aggacaacau ggacaagaug caagucgacc aagaggaggg ccaccagaag ugccacgccg     1680

agcauacccc ggaggaagag aucgaccaua ccggggcgaa gaccaaaagc gccgugagcg     1740

auaagcaaga uaggcucaac caaaccuuga agaaggggaa aguaaagucg aucgacuugc     1800

ccauacaauc gucguugugc cgccaauugg ggcaagacuu guuaaauucg uauaucgaga     1860

acgaaggcaa aaugauaaug caagacaaac ucgaaaagga gcgcaacgac gccaaaaacg     1920

cggucgagga guacgucuac gacuuccgcg aucgcuuagg gaccguguac gagaaguuua     1980

uaaccccgga agaucucucg aaauuaagcg ccguccucga ggauaccgaa aacugguugu     2040

acgaggaugg ggaagaucaa ccgaagcagg ucuacgucga caaauugcag gaguugaaaa     2100

aguaugggca accgauccaa augaaauaua uggaacacga agaacgcccg aaggcgcuca     2160

acgaucucgg gaaaaaaaua caauugguga ugaaagucau cgaagccuac cgcaauaaag     2220

acgagcgcua cgaccacuua gacccgaccg aaauggagaa agucgagaag ugcauaucgg     2280

acgcgauguc gugguuaaac ucgaaaauga acgcccaaaa uaaguugucg uugacccagg     2340

acccggucgu caaggucagc gagaucgucg ccaaaagcaa agaguuagac aacuuuugca     2400

auccgauaau cuauaaaccg aaaccgaagg ccgagguccc ggaggauaag ccgaaggcca     2460

acucggaaca uaacgggccg auggacgggc aaucggggac cgagaccaag agcgacagca     2520

ccaaggauuc gagccaacac accaaaagua gcggggaaau ggaggucgau ugaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  5704
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt10)

<400>  5704
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaau       60

ugaguuuagu cgcggccaug uuauuauuau ugucggccgc cagagcggaa gaagaagaua      120

aaaaagaaga ugucgggacc gucgugggga uagauuuagg cacgacguau aguugugugg      180

gggucuuuaa aaaugggagg gucgaaauaa uagcgaauga ccaagggaau aggauaaccc      240

ccaguuacgu ggcguuuacc ccggagggcg agagguuaau cggggacgcg gcgaaaaauc      300

aauugacgag uaauccggaa aauaccgugu ucgaugcgaa aagauugaua gggaggaccu      360

ggaacgaucc cagcguccaa caagauauaa aauuucuccc cuuuaaaguc gucgagaaaa      420

agaccaagcc guauauccag gucgacaucg gggggggcca gaccaaaacc uucgccccgg      480

aggagaucag cgcgaugguc uugaccaaga ugaaggagac ggccgaagcc uaccucggga      540

aaaaagucac gcacgccguc gucaccgucc cggcguacuu caacgacgcg cagaggcagg      600

ccacgaagga ugccgggacc aucgccgggu ugaacgucau gcgcauaaua aaugaaccga      660

ccgccgccgc caucgccuac ggguuagaca aacgcgaagg cgaaaaaaau auauuagucu      720

ucgauuuagg gggggggacg uuugacguca gcuuguugac gaucgauaac gggguguuug      780

aggucgucgc gaccaacggg gacacccacu uaggggggga ggauuucgau caaaggguga      840

uggagcauuu uauaaaguua uauaagaaaa aaaccgggaa ggacgugcgc aaggauaacc      900

gcgccgucca aaaguugaga agggaagucg agaaagcgaa gagagcguua agcagccaac      960

accaggcccg caucgagauc gaaaguuuuu acgaggggga ggauuucagc gaaacguuaa     1020

ccagagcgaa guucgaggaa uugaauaugg acuuauuuag aagcaccaug aaaccggugc     1080

aaaagguccu cgaggacagc gaccucaaaa aaagcgacau cgacgagauc gucuuggucg     1140

gggggagcac caggaucccg aaaauccaac aguuagucaa ggaauuuuuu aacgggaaag     1200

agccgaguag ggggaucaau ccggacgagg ccgucgccua cggggccgcc gugcaagccg     1260

gggucuugag cggggaccag gacaccgggg auuuagucuu auuggacguc ugcccguuga     1320

ccuuggggau cgagaccguc ggggggguga ugacgaaguu aaucccgcgc aauaccgucg     1380

ucccgacgaa aaaaagccaa auauucagca ccgccagcga caaccagccg accgucacca     1440

uaaaagugua cgagggggag cgcccguuaa ccaaggauaa ccacuuguua gggaccuucg     1500

acuuaaccgg gaucccgccg gccccgaggg gcgugccgca aaucgaggug acguucgaaa     1560

ucgacgucaa cgggaucuug agggucaccg ccgaggauaa agggaccggc aauaagaaca     1620

aaauaaccau aacgaacgau caaaacaggu uaaccccgga ggagauagag cgcaugguca     1680

acgacgccga aaaauucgcc gaagaggaua agaaauugaa agaaaggauc gacacccgca     1740

acgaacucga gucguacgcg uacagcuuga aaaaccaaau cggggacaag gagaaauuag     1800

gggggaaguu gaguagcgag gacaaagaaa cgauggagaa ggccgucgag gagaaaaucg     1860

agugguuaga gucgcaucag gacgccgaua ucgaggauuu uaaggccaaa aaaaaagagu     1920

uagaggagau cguccagccg aucauaucga aguuguacgg gucggccggg ccgccgccga     1980

ccggggagga agacaccgcc gagaaggacg aacucugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  5705
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt10)

<400>  5705
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

cgccgagaga auuggccguc gggauagauu uagggacgac guauagcugu gucggggucu      120

uccaacaagg gagggucgaa auauuagcga augaucaagg gaauaggacg accccgucgu      180

augucgcguu uacggauacg gaaagauuag ugggcgaugc cgcgaaaucg caagccgcgu      240

uaaauccgca uaauacgguc uuugacgcga aaagauuaau aggcaggaaa uuugccgaua      300

cgaccgucca aagcgauaug aaacauuggc cguuuagagu cgucucggaa ggggggaaac      360

cgaaagucag ggucuguuau aggggcgaag auaaaaccuu uuauccggaa gaaauaagca      420

guauggucuu aucgaaaaug aaagaaaccg cggaagccua uuuagggcaa ccggucaaac      480

augccgucau aacggucccg gcguacuuua acgauagcca aaggcaagcg acgaaagaug      540

ccggcgcgau agccggcuug aauguccuca gaauaauaaa cgaaccgacc gccgccgcga      600

uagcguacgg cuuagauaga agaggggccg gggaaaggaa ugucuugauc uucgauuuag      660

ggggcgggac guuugacguc agcgucuuga guaucgaugc cgggguguuc gaagucaagg      720

cgaccgccgg ggacacgcau uuaggggggg aagauuuuga uaauagauug gucaaucauu      780

uuauggagga guuuagaaga aaacacggca aagauuuauc gggcaauaaa agggcguuaa      840

ggcgcuuaag gaccgcgugc gaaagggcga aaaggacguu aaguaguucg acgcaagcga      900

cguuagaaau cgauaguuua uuugaagggg ucgauuuuua uaccaguaua accagggcga      960

gguucgaaga guuauguagc gauuuguuua ggucgacguu agaacccguc gaaaaagcgu     1020

uaagagacgc gaaauuagau aaagcgcaaa uccacgaugu gguguuaguc ggcgggagua     1080

ccaggauacc gaaaguccaa aaacucuuac aagauuuuuu uaaugggaaa gaauuaaaua     1140

aaucgauaaa uccggacgaa gccgucgcgu acggcgccgc cguccaagcc gcgguccuca     1200

ugggcgauaa gugcgaaaag guccaagacu uguuauuauu agacgucgcc ccgcucagcu     1260

uaggcuuaga aaccgccggg ggcgucauga cgaccuuaau acaacgcaau gcgaccauac     1320

cgacgaaaca aacgcaaacc uuuacgacgu auagcgauaa ucaaccgggc guguuuauac     1380

aagucuacga aggggaacgc gcgaugacga aagauaauaa uuuauuaggc agguucgagu     1440

ugucggggau accgccggcg ccgagggggg ugccgcaaau cgaagucacc uucgauaucg     1500

acgccaacgg gauauuaucg gucaccgcga ccgaucgcuc gaccgggaaa gccaauaaaa     1560

uaacgauaac gaacgauaaa gggagauuau cgaaagaaga agucgaacgc augguccacg     1620

aggcggaaca auauaaagcc gaagacgaag cgcaacgcga ucgcgucgcc gcgaagaaua     1680

gcuuagaagc gcacguguuu cacgucaagg ggagccucca ggaagagucg uugcgcgaua     1740

aaaucccgga ggaagaucgc aggaagaugc aggauaaaug cagagaggug uuggcguggu     1800

uagaacauaa ucaauuagcc gaaaaagaag aauacgaaca ccaaaaacgc gaauuagaac     1860

agauaugcag gccgauauuu agucgcuugu acggcggccc gggggugccg ggcgggucgu     1920

cgugcgggac ccaggcgagg caaggcgauc cgucgacggg gccgauaauc gaagaagucg     1980

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  5706
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt10)

<400>  5706
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

cgccccgcga gcuggccgug ggcaucgacc ucgggaccac cuacagcugc gucggcgugu      120

uccagcaggg gcggguggag auccuggcca acgaccaggg caaccgcacg accccguccu      180

acgucgccuu caccgacacc gagcggcugg ugggggacgc cgccaagucg caggccgcgc      240

ucaaccccca caacacggug uucgacgcca agcgcuuaau cggccggaag uucgccgaca      300

ccaccgucca gagcgacaug aagcacuggc ccuuccaggu ggugucggag ggcgggaagc      360

ccaaggucag ggugugcuac cggggcgagg acaagaccuu cuacccggag gagaucagca      420

gcaugguguu auccaagaug aaggagacgg ccgaggcgua ccucgggcag cccgucaagc      480

acgccgugau caccgugccc accuacuucu cgaacagcca gaggcaggcc accaaggacg      540

ccggcgccau cgcggggcug aaggucuuac ccaucaucaa cgaggccacg gccgccgcca      600

ucgcguacgg ccucgacaga cgcggcgccg ggaagcggaa cgugcugauc uucgacuuag      660

gcgggggcac cuucgacgug agcgucuuga guaucgacgc cggcguguuc gaggugaagg      720

ccaccgccgg ggacacccac uuaggcgggg aggacuucga caaccgccug gucaaccacu      780

ucauggagga guucagacgc aagcacggca aggaccucuc ggggaacaag cgggcguuaa      840

ggcgguuaag gacggccugc gagcgggcca agaggacccc gaguagcucc acccaggcca      900

cccucgagau cgacagcuua uucgagggcg uggacuucua caagaguauc acgcgggcca      960

gguucgagga guuaugcagc gacuuguuca gguccaccuu agagcccgug gagaaggcgu     1020

uaagagacgc caagcucgac aaggcccaga uccacgacuu cgucuuaggc gggggccugc     1080

acagccaccc ccagggggcc gagguggcgg ccggccuccu gcagcgccag ggggccgagc     1140

aggagcacca gcccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  5707
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt10)

<400>  5707
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucga       60

aggggccggc gguagguaua gacuuaggca cgacguacuc gugcguaggg guauuccagc      120

acggcaaggu agagaucauc gcgaacgacc aggggaaccg aacaacgccg ucguacguag      180

cauucaccga cacggagcgc uuaauaggcg acgcggcgaa gaaccaggua gcgaugaacc      240

cgacuaacac ggucuucgac gcgaagcggu uaaucggucg acgguucgac gacgcgguag      300

uacagucgga caugaagcac uggcccuuca uggucguuaa cgacgcaggu agaccgaagg      360

uacaggugga guacaagggc gagaccaagu cguucuaccc ggaggagguc ucgucgaugg      420

uguuaaccaa gaugaaggag aucgcggagg cguacuuggg uaagacggug acgaacgcag      480

ucguuacggu cccggcguac uucaacgaca gucagcgaca ggcgacuaag gacgcgggua      540

cgaucgcggg auuaaacguc uuacgaauca ucaacgagcc gacggcggcc gcgauagcgu      600

acgggcuaga caagaaggua ggugcggaga ggaacguauu aaucuucgac uuggggggcg      660

ggacguucga cguaucgaua uuaaccaucg aggacgguau uuucgaggua aagaguaccg      720

caggggacac ccacuuaggg ggggaggacu ucgacaaccg uaugguaaac cacuucauag      780

cggaguucaa gcggaagcac aagaaggaca uaucggagaa caagcgcgcc guacgacguu      840

uacggacggc gugcgagaga gcgaagcgaa ccuuaaguuc gaguacucag gcaucgauag      900

agauagacuc guuauacgag gggaucgacu ucuacacguc gaucacgcga gcgcgguucg      960

aggaguugaa cgccgacuug uuccgaggga cgcuugaccc gguggagaag gcguuacggg     1020

acgcuaaguu agacaagagu cagauacacg acauaguauu aguagggggg ucgacgcgaa     1080

ucccuaagau acagaaguua uugcaggacu ucuucaacgg caaggaguua aacaagagua     1140

uaaacccgga cgaggcagua gccuacgggg cggcgguaca ggcggcgauu cucucgggug     1200

acaagucgga gaacgugcag gacuuauuau uauuagacgu aacgcccuua ucgcucggga     1260

ucgagacggc ggggggggua augacgguau ugaucaagag gaacacgacg auaccgacga     1320

agcaaacgca gacguucacg accuacucgg acaaccagcc gggcguauua auacagguau     1380

acgagggcga gcgggccaug acgaaggaca acaaccuuuu agguaaguuc gaguuaacgg     1440

guauuccgcc ggcgccgagg gggguaccgc aaaucgaggu aacguucgac auagacgcga     1500

acgggauccu uaacguaagu gcgguagaca agucgacggg uaaggagaac aagaucacga     1560

uaacgaacga caagggccgc uuaaguaagg aggacaucga gcgcauggua caggaggcgg     1620

agaaguacaa ggcggaggac gagaagcagc gagacaaggu aucgucgaag aacucguugg     1680

agaguuacgc guucaacaug aaggcgacgg uagaggacga gaaguuacag gguaagauca     1740

acgacgagga caagcagaag aucuuggaca agugcaacga gauaaucaac ugguuagaca     1800

agaaccagac ggcggagaag gaggaguucg agcaccagca aaaggaguua gagaagguau     1860

gcaacccgau cauaacgaag cuauaccagu ccgcgggugg gaugccgggg gggaugccgg     1920

gcgguuuccc cggagggggu gccccgccga gugggggggc gucgucgggc ccgacgaucg     1980

aggaggucga cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  5708
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt10)

<400>  5708
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaucu       60

cggcgucgag ggccgccgcc gcgagguugg ucggggcggc cgcgaguaga gggccgaccg      120

cggcgaggca ucaagacucg uggaacgggu ugucgcacga agccuuccgc uuggucagcc      180

gcagagacua cgccagcgag gcgauaaaag gggccgucgu cgggaucgau cucgggacca      240

cgaauaguug ugucgccguc auggagggga agcaagcgaa agucuuagaa aacgcggagg      300

gggcgcgcac gacgccgagc gucgucgcgu ucaccgccga cggggaaagg uuggucggga      360

ugcccgcgaa aaggcaagcc gugacgaauc cgaauaauac cuucuacgcc acgaaaaggu      420

ugaucgggag aagguacgac gacccggagg uccaaaagga uaucaagaac gucccguuua      480

agaucgugag ggcgaguaac ggggacgcgu gggucgaagc ccauggcaag cucuacagcc      540

ccucgcaaau aggggccuuc guccucauga aaaugaagga aaccgccgag aacuaucucg      600

gccauaccgc caagaacgcc gucauaaccg ugccggccua cuuuaacgau agccaacgcc      660

aagcgaccaa agacgccggg caaauuagcg gguuaaacgu cuugagaguc aucaacgaac      720

cgaccgccgc cgccuuggcg uacggguugg auaagagcga ggauaaggua aucgccgucu      780

acgaccucgg gggggggacc uucgacauca gcauauuaga gauccaaaag ggggucuucg      840

aagucaagag uaccaacggc gacacguuuc ucgggggcga ggauuucgau caagcgcucu      900

ugagacauau cgucaaagaa uuuaaacgcg aaaccggcgu cgaccucacc aaagauaaua      960

uggccuugca acgcgucaga gaggccgccg agaaagccaa gugcgaguug aguagcagcg     1020

uccaaaccga uauaaaccuc ccguacuuga ccauggacag cagcgggccg aaacaccuca     1080

acaugaaacu cacgagggcc caguucgagg gcaucgugac cgacuugaua cgccgcacca     1140

uagccccgug ucaaaaggcc augcaggacg ccgagguauc gaaaucggau aucggggagg     1200

ucauauuggu cggggggaug acccgcaugc cgaaagucca acaaaccguc caagauuugu     1260

ucgggcgcgc gccgucgaaa gccgugaacc cggacgaagc cgucgcgauc ggggccgcga     1320

uccaaggggg gguccucgcg ggggacguga ccgacgucuu auuguuggac gugaccccgc     1380

ucagcuuagg gaucgagacc uugggggggg uguucacgaa guugaucaac cgcaacacga     1440

ccaucccgac gaaaaaaucg caagucuuua gcaccgcggc cgacgggcag acccaggucg     1500

agaucaaggu cugucaaggg gagcgcgaaa uggccgggga uaauaaguug uuggggcaau     1560

ucacccucau cgggaucccg ccggcgccga gggggguccc gcaaaucgag gucaccuucg     1620

auaucgacgc gaacggcauc guccacguca gcgccaagga caaggggacc gggagggaac     1680

aacaaaucgu cauacaaagc agcggggggc ucucgaagga cgacaucgag aacaugguca     1740

aaaacgccga aaaauacgcc gaggaggaua gaaggaaaaa agagaggguc gaggcgguca     1800

auauggccga ggggauaauc caugauaccg aaacgaaaau ggaagaguuu aaagaucagc     1860

ucccggccga cgaauguaau aaauuaaagg aggaaaucag uaagaugcgc gaauuguuag     1920

cccgcaaaga uucggaaacc ggggagaaca uccgccaagc cgcgaguagc uugcaacaag     1980

ccagcuuaaa auuauuugag auggccuaua aaaaaauggc cagcgaaagg gaggggagcg     2040

ggucgagcgg gaccggcgag caaaaagagg accagaaaga agagaaacaa ugaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  5709
<211>  2410
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt10)

<400>  5709
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

acaaggaagc aggggguucg gacggcccuc gugagacugc accuacuucg gcguacucuu      120

cgccggcucg aucguuaggu gacacuggga ucacgccguu aaguccgucg cacauaguaa      180

acgauacgga caguaacgua ucggagcagc agucguucuu aguaguagua gcgguggacu      240

ucgguaccac gucgucgggu uacgcguacu cguucacgaa agagccggag ugcauacacg      300

ucaugcggag gugggagggg ggagacccgg gcguaaguaa ccagaagaca ccuacgacga      360

uauuauuaac gccggagcgg aaguuccacu cguucgguua cgcggcccgu gacuucuacc      420

acgacuuaga cccaaacgag gcaaagcaau gguuauacuu ggagaaauuc aaaaugaagu      480

uacacacuac gggagacuua acgauggaca cugacuugac ugccgcgaac gguaaaaagg      540

uaaaggcgcu cgagaucuuc gcguacgcau uacaguacuu caaggagcag gccuuaaagg      600

agcucucuga ccaggcuggg ucagaguucg agaacaguga cguaaggugg guaauaacug      660

uaccggcgau auggaagcag ccagcgaagc aguucaugcg ccaggcagcg uaccaggcgg      720

gguuagcguc gccggagaac agugagcagu uaauaaucgc uuuagaaccg gaagcggcgu      780

cgauauacug ccggaaguua cguuuacacc aaaugauaga guuaucaagu aaggcggcgg      840

uuaacgggua cucagguucg gacacuguug gggcggguuu cacgcaggcg aaggagcaca      900

uccgacgaaa caggcaaucg cgcacauucc ucgucgagaa cguuauuggc gagauuugga      960

gugagcuuga ggagggagac aaguacguag uaguagacuc ggguggggga acuguugauu     1020

uaacgguaca ccaaauuagg cucccagagg gucacuuaaa ggagcucuac aaggccacgg     1080

gugguccgua cgguagucuc gggguugacu acgaguucga gaaguugcuc uacaagaucu     1140

ucggugagga cuucauagag caguuuaaga ucaagcgucc ggcggcgugg guagaccuca     1200

ugauagcuuu cgaaucgcga aagcgcgccg cagcgccgga ccgaacgaac ccuuugaaca     1260

ucacguuacc guucucguuc auagacuacu acaagaaguu ccguggacac ucgguagagc     1320

acgcguuacg aaagaguaac guagacuucg uaaagugguc gagucagggu augcuucgca     1380

ugucgcccga cgcgaugaac gcguuauuca agccuacuau cgacucgaua auagaacacu     1440

ugagggacuu auuccagaag ccggagguau cgacgguaaa guucuuauuc uuagucgggg     1500

gguucgcaga ggcgccguug uuacagcagg caguucaggc ggcguucggu gaccagugcc     1560

gaauaauaau accccaggac guaggguuaa cgaucuugaa gggggcgguu uuauucgggu     1620

uagacccggc cguaauaaag guucgacguu cacccuugac uuacgguguc ggcgucuuaa     1680

accgauacgu agaggggaag cacccaccgg aaaaguuguu agucaaggac ggaacacgau     1740

ggugcacgga cguauucgac aaguucauau cggccgacca aaguguagcg uuaggcgagu     1800

uaguaaagcg aucguauacg ccugccaagc cgucgcaauu aguaauaguc aucaacaucu     1860

acaguucgga gcacgacaac guaaguuuua uaacggaccc gggagucaag aagugcggaa     1920

cauuaagguu agacuugacg gguacgucgg guaccgcggu uccagcgcgc cgagagauac     1980

agacgcucau gcaguucggu gacacggaga uaaaggcgac ggcgauagac aucgcuacgu     2040

cuaagucggu aaaggucggu aucgacuuuc ucaacuacug aggacuagug caucacauuu     2100

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2160

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2220

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2280

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     2400

caccagaauu                                                            2410


<210>  5710
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt10)

<400>  5710
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguuag       60

caguacccga gaugggauua caagguuuau acauagguuc gucgcccgag cguucgccgg      120

uuccgucgcc uccggggucg ccacgcacgc aagagucgug cgggauagca ccuuuaacuc      180

cuucccagag uccuaagccg gaaguucgug caccgcagca ggcaucguuc agugucguag      240

ucgcuauaga cuucgguaca acaucgucgg guuacgccuu cucguucgcu ucggacccgg      300

aggcaaucca uaugaugcgu aagugggagg guggugaccc uggugucgcg caccaaaaga      360

cgccuacgug cuuauuauua acgccugagg gggcguucca cucguucgga uacacggcgc      420

gagacuacua ccacgacuug gaccccgagg aggcucgcga cugguuauac uucgaaaagu      480

ucaaaaugaa gauacacucg gcgacugacu uaacguuaaa gacacaacuc gaggcgguua      540

acgggaagac aaugccggcg uuagaggucu ucgcgcacgc guugagguuc uuccgcgagc      600

acgcgcucca ggaguuacga gagcaaucgc cgucauugcc ggagaaagac acgguccguu      660

gggucuuaac cgucccggcg aucuggaagc aaccggcgaa acaguucaug cgagaggcgg      720

cuuauuuagc gggguuagua ucgcgugaga acgcggagca auuauuaaua gcguuagagc      780

cggaggcggc gucaguuuac ugucgaaagu ugcgauugca ccaguuguua gauuuaucag      840

gaagggcgcc gggaggcggg cgauugggcg agaggcgauc gauagacucg ucguuccgac      900

aggcgcgcga gcagcuccgu cguucgaggc auucgcggac guucuuagua gagucgggug      960

uuggugaguu augggcggaa augcaggcgg gugaccguua cguagucgcu gacugcggug     1020

gggggacggu agacuuaaca guucaccagu uagagcagcc acacgguacg uugaaagagc     1080

uuuacaaggc gucaggaggg ccguacgggg ccguaggggu ugauuuagcg uucgagcagu     1140

ugcucugccg gaucuucggc gaggacuuca ucgcaacauu caagcgccag cguccagcgg     1200

caugggucga cuuaacaaua gcguucgagg cacguaagcg gacggcagga ccgcaucgag     1260

cgggugcauu aaacauaagu uuaccguucu cguucauaga cuucuaccgg aagcaacgcg     1320

gucacaacgu agagacggcg cucaggcgaa guucggucaa cuucguaaag uggaguucgc     1380

aggguauguu gcgcaugagu ugcgaggcga ugaacgaguu auuccagcca acaguuucag     1440

gcauuauaca gcacauugag gcauuauugg cgcgccccga gguacagggg gucaagcucu     1500

uauucuuggu cggaggauuc gcggagucgg caguauuaca gcacgcagua caagcggcuu     1560

uaggugcgag gggcuuacgc guaguaguac cccacgacgu cgguuugacu auauugaagg     1620

gcgccguuuu auucggucag gcuccgggag ucgucagggu ucgacggucu ccauuaacuu     1680

acggugucgg uguauuaaac cguuucgucc ccgguaggca cccgccggag aaguuauugg     1740

uacgagacgg ucgaaggugg ugcacggacg uguucgagcg uuucguagca gcggaacagu     1800

cagucgcguu aggagaggag guaaggcguu cguacugucc ugcaaggcca ggacagcguc     1860

gagucuuaau uaacuuguau uguugcgcag cggaggacgc acgauucaua acugacccgg     1920

guguacggaa gugcggugcc uuaaguuugg aguuagaacc ggcggacugc ggucaggaca     1980

cggcgggugc accaccgggu cgucgagaga uccgagcagc gaugcaauuc ggugauacug     2040

agauaaaggu gacggcggua gacguuucga cuaacagguc gguccgagca ucgaucgacu     2100

ucuuaucgaa uugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  5711
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt10)

<400>  5711
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcgc       60

gcgaaaugac uauacucggg ucugcggucu uaacguuacu cuuagcaggu uacuuagcgc      120

agcaguaccu uccucuuccg acacccaagg uaauaggaau agacuuaggu acgacauacu      180

gcagugucgg aguauucuuc ccgggaacug guaaggucaa gguaauaccg gacgagaacg      240

gacacaucuc uaucccgucg auggucucgu ucacggauaa cgacguuuac gucggguacg      300

agucggucga guuagcggac ucuaacccgc agaacacgau cuacgacgcu aagcgauuca      360

ucgguaagau auucacggcg gaggaguuag aggcagagau agguagguac ccguucaagg      420

ucuugaacaa gaacgggaug guagaguucu caguaaccuc gaacgagacg aucacuguaa      480

gucccgagua cgucgguuca cguuuacuau uaaaguugaa ggagauggcg gaggcguacu      540

ugggcaugcc gguagcgaac gcaguaauau cgguccccgc cgaguucgac uuaaagcaac      600

gaaacucgac gaucgaggcg gcgaacuuag cggggcuuaa gauccuucga gugaucaacg      660

agccgacggc ggcggcgaug gccuacgggu uacacaaggc cgacguauuc cacgugcuug      720

ucaucgacuu aggagguggg acacucgacg ucucgcuuuu gaacaagcag gguggaaugu      780

ucuugacgcg ugcgaugucg gguaacaaca aguugggugg gcaggacuuc aaccagcgau      840

uauuacagua cuuguacaag caaauuuacc agacguacgg uuucgucccg ucacgaaagg      900

aagagauaca ucgauuaagg caggcagucg agaugguaaa guugaacuug acguuacacc      960

agucggcgca auuaaguguc uuguuaacgg uugaggagca ggaccguaag gagccgcacu     1020

cgucggacac cgaguuaccg aaggacaagu ugucgucggc ugacgaccac aggguaaacu     1080

cggguuucgg cagggguuua ucagacaaga agucgggcga gucgcaggua cucuucgaga     1140

cggagaucag ucgaaaguua uucgacacgu uaaacgagga cuuauuccaa aagaucuuag     1200

uuccgaucca gcagguuuua aaggaggguc acuuagagaa gacggagaua gacgagguug     1260

ucuuggucgg ugguucgacg cgaauccccc gaaucaggca gguaauacag gaguucuucg     1320

ggaaggaccc aaacacgucg gucgauccgg acuuagcggu uguuaccggu guugcgauuc     1380

aggccgggau agacgggggu ucguggccgu uacagguauc agcgcucgag auaccgaaca     1440

agcacuugca gaagacgaac uucaacugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  5712
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt10)

<400>  5712
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

cgauaggggu ccauuuaggg uguacgagcg cgugcgucgc gguguacaaa gacgggagag      120

ccggggucgu cgccaacgac gcgggggaua gggucacccc ggccgucguc gccuauagcg      180

agaacgagga aaucgucggg cucgccgcca agcagucgcg cauccgcaac aucagcaaua      240

ccgucaugaa ggucaaacaa auauuagggc gcucgaguuc ggauccgcag gcgcaaaagu      300

auauagccga gucgaagugc cucgugaucg aaaagaacgg caagcucagg uacgagaucg      360

acaccgggga ggagaccaag uucgucaauc cggaggacgu cgcgcgcuua auuuuuucga      420

aaaugaagga gaccgcccac agcguccucg ggagcgacgc caacgacguc gucaucaccg      480

ugcccuucga cuucggggaa aaacagaaga acgccuuggg ggaggccgcc cgcgccgccg      540

gguucaacgu ccucaggcuc auccaugaac ccagcgccgc cuuguuggcc uacgggaucg      600

ggcaggauag uccgaccggg aagucgaaca uccucgucuu uaaauugggg gggaccaguc      660

ucagcuuguc ggugauggag gucaauucgg ggaucuacag agucuugagc acgaauaccg      720

acgacaauau agggggggcc cauuuuaccg agacgcucgc ccaauacuug gccagcgaau      780

uucagcgcag uuuuaagcac gacguccgcg ggaacgccag ggcgaugaug aagcucacca      840

auucggccga ggucgccaaa cacagccuca gcacgcucgg gucggcgaau ugcuuuuugg      900

auagccucua cgaggggcag gacuucgacu guaacgucag ucgcgcccgc uucgaguugu      960

ugugcagccc guuguucaac aaaugcaucg aggccauacg cggguugcuc gaccagaacg     1020

gguuuaccgc cgacgacaua aauaaagucg uguugugcgg gggcagcagc aggauaccga     1080

aauugcaaca auuaaucaag gacuuguuuc cggccgucga auuguugaac agcauaccgc     1140

cggacgaggu cauaccgauc ggggccgcca ucgaggccgg gaucuugauc ggcaaggaga     1200

auuuacucgu cgaagauagc uugaugaucg aaugcagcgc gcgcgacauc cucgucaaag     1260

gggucgauga gagcggggcg ucgcgcuuua ccgucuuauu cccgagcggc accccgcucc     1320

cggccaggcg ccagcauacc cuccaagcgc cggggucgau cagcagcguc uguuuggagu     1380

uguacgaaag cgacggcaaa aauagcgcga aagaagagac gaaauucgcc caagucgucu     1440

ugcaagaucu cgauaagaag gagaacgggc ucagggacau ccucgccguc uugaccauga     1500

agcgcgacgg gagccuccac gucaccugua ccgaccaaga aaccgggaag ugcgaggcca     1560

uaagcaucga aaucgccagc ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  5713
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt10)

<400>  5713
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccg       60

ugguaggacu cgacgucggg agccaaagcu gcuacauagc gguagccagg gcaggcggga      120

uagagacgau cgccaacgag uucuccgauc gcugcacacc cagcgucauc agcuuugguu      180

cuaaaaacag gacuauagga guggccgcga aaaaccaaca aauaacccau gcaaacaaca      240

ccgucagcaa cuucaaacga uuccacggac gugccuucaa cgacccguuu auacaaaaag      300

aaaaagaaaa ccuauccuac gaccuagucc cccucaagaa uggaggcgug ggcaucaaag      360

uuauguauau gggagaagaa cacuuguucu caguagaaca gauaaccgcc augcuacuaa      420

caaaacugaa ggaaaccgca gagaacaguc ugaagaaacc ugucaccgac ugcguaaucu      480

ccguacccuc cuucuucacc gacgcagaac ggagauccgu acuagacgca gcccaaauag      540

uaggccuaaa cugccuccgc uugaugaacg auaugacggc cguagcacuc aacuauggga      600

uuuacaaaca agaccuccca agccucgacg aaaaaccccg cauaguaguc uucgucgaca      660

ugggacacuc agcauuccag guaagcgcau gcgccuucaa caaaggaaaa cucaaagucu      720

uaggcacggc uuucgacccc uuccuaggcg ggaaaaauuu cgacgagaaa cucgucgaac      780

acuucugcgc cgaguucaaa accaaauaca aacucgacgc aaagagcaaa auccgagccc      840

uccuacgcuu auaccaggaa ugcgaaaagc uaaagaaauu gauguccucc aacuccaccg      900

accuacccuu aaacaucgaa uguuucauga acgacaagga cgucagcgga aagaugaaca      960

gaucccaguu cgaggagcuc ugcgccgagu uauuacaaaa gauagaaguc ccccucuaca     1020

gccuucucga acagacccac cucaaaguag aagacguuuc agccgucgaa aucgucggcg     1080

gagcaacacg cauccccgcg gucaaagaac gcaucgccaa auucuucggg aaggacauau     1140

ccaccacccu aaacgcagac gaagcagugg cacgcgggug ugcccuccag ugcgccaucu     1200

uaagccccgc auucaaagua cgagaguucu caguaaccga ugccgucccg uucccaauaa     1260

gccugauaug gaaccacgac agcgaggaca ccgaaggugu ccacgaaguc uucagucgaa     1320

accacgcggc cccauucuca aaaguauuaa cguuccuccg acgcggaccc uucgaacucg     1380

aagcauucua cagcgacccg caaggcguac cguacccuga ggcaaagauu ggcagguucg     1440

uaguccagaa cgucuccgca caaaaagaug gcgagaaaag ccgcguaaag gucaaagucc     1500

gagucaauac acacggaauc uucaccauuu ccaccgccuc aaugguagaa aaagucccca     1560

cagaagaaaa cgagaugagc ucugaagccg acauggagug ccucaaccaa cgcccacccg     1620

aaaaccccga caccgacaag aacguccaac aagacaacag cgaagcagga acccagcccc     1680

aaguccaaac cgacgcacaa cagaccagcc agagcccacc cucccccgag cucacaucag     1740

aagaaaauaa gaucccagac gcagacaagg ccaacgaaaa gaaagucgac cagcccccgg     1800

aggccaagaa acccaaaauc aaagugguca acguagaacu ccccaucgaa gcaaaccugg     1860

ucuggcagcu agguaaagac uuauuaaaca uguacaucga aaccgaaggc aaaaugauaa     1920

ugcaagauaa acucgaaaaa gaacgcaacg acgccaaaaa cgcagucgaa gaauacguau     1980

acgaguuccg ggacaaauua ugcggcccau acgaaaaauu caucugugaa caagaccacc     2040

aaaacuuucu acguuuauua accgaaaccg aagacuggcu cuacgaagaa ggcgaagauc     2100

aagcaaaaca ggcuuacguc gauaaacucg aagaacuaau gaaaaucgga acgccgguca     2160

aagugcgguu ccaagaagca gaagaacguc ccaaaauguu cgaggaacuc ggacaaagac     2220

uccaacacua cgcgaaaauc gccgccgacu uccgcaacaa agacgagaag uacaaccaca     2280

ucgacgaauc agaaaugaag aaaguagaaa agucggucaa cgaaguaaug gaauggauga     2340

acaacguaau gaacgcccaa gccaaaaagu cccucgacca agacccaguc guccgagcac     2400

aagaaaucaa aaccaaaauu aaggaacuca acaauaccug cgagcccguc guaacgcaac     2460

cgaaaccaaa aauagaaucc cccaaacucg aacgaacccc caacgggccg aacaucgaca     2520

agaaagaaga agaccucgag gacaaaaaca acuucggagc agaaccacca caccaaaacg     2580

gcgaaugcua cccaaacgag aaaaacagcg ucaacaugga ccucgauuga ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  5714
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt10)

<400>  5714
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccg       60

auaagguccg ccgccaacgc ccccgccgca gggugugcug ggcgcucguc gccgucuugc      120

ucgccgauuu acucgccuua ucggacaccu uagccgucau gagcgucgau uuagggucgg      180

aaaguaugaa agucgcgauc gugaagccgg gggucccgau ggagaucgug cucaacaaag      240

agagcagacg caagaccccc gucauaguca cguuaaagga gaacgagcgc uuuuucgggg      300

auucggccgc cucgauggcc aucaaaaacc cgaaagccac cuugagguau uuucaacauu      360

uguuaggcaa acaagccgac aauccgcacg ucgccuugua ucaagcgagg uuucccgaac      420

augaauuaac cuuugauccg caacgccaaa ccguccauuu ccaaauaucg agccaauuac      480

aauuuagccc ggaagagguc cucgggaugg ucuugaacua cagcaggagc uuggccgagg      540

acuucgccga acaaccgaua aaagacgccg ucauaacggu cccgguguuu uuuaaucaag      600

cggaaaggag ggccgucuua caagccgcca ggauggccgg guugaagguc uuacaauuga      660

uaaacgauaa uacggcgacc gcguugucgu acgggguguu uaggagaaag gacaucaaua      720

cgaccgcgca aaacauaaug uuuuacgaua uggggagcgg gucgacgguc uguacgaucg      780

ucacguauca aauggucaaa accaaagagg ccggcaugca accgcaauua caaauaagag      840

gggucggguu cgauaggacg uuaggcgggu uagaaaugga auugagauug agggagaggu      900

uagccggcuu guuuaacgaa caaaggaaag ggcaacgcgc caaagacguc agagaaaauc      960

ccagggcgau ggcgaaauua uuaagggaag ccaacagauu gaagacggug uugucggcga     1020

augccgauca uauggcccaa aucgaggggu uaauggacga cgucgauuuu aaagccaagg     1080

ucaccagggu cgaguucgaa gaacucugcg ccgaucucuu cgaaagaguc ccgggcccgg     1140

uccaacaagc guugcaaucg gcggagaugu cguuagacga aaucgaacaa gucauauuag     1200

ucgggggcgc gaccagagug ccgcgcgucc aagaagucuu auuaaaagcg gucgggaaag     1260

aagaauuagg caaaaauaua aacgccgacg aggccgcggc gaugggcgcc gucuaucaag     1320

ccgccgccuu gucgaaggcg uucaagguca aaccguucgu ggugagggac gccgucgugu     1380

auccgauauu agucgaauuu acccgcgaag ucgaagaaga accgggcauc cauucguuaa     1440

aacauaacaa gagagucuug uuuagcagaa ugggcccgua uccgcagagg aaggugauaa     1500

cguucaauag guauucgcac gacuuuaauu uucauauaaa uuauggggau uuaggguuuu     1560

uaggcccgga ggacuugaga gucuucggga gucaaaacuu aacgaccguc aaauugaagg     1620

gcgucgggga uucguuuaaa aaauacccgg auuaugaaag uaaagggaua aaagcccauu     1680

uuaauuuaga cgaaucgggg gucuugucgu uggaucgcgu cgaaagcguc uucgaaaccu     1740

uagucgaaga uucggccgag gaagagagca ccuugacgaa guuggggaau acgaucaguu     1800

cguuauucgg gggggggacg accccggacg cgaaagaaaa cgggaccgac accgugcaag     1860

aagaggaaga aucgccggcc gaaggcucga aagaugaacc gggcgaacaa gucgaauuga     1920

aagaagaggc cgaagcgccg gucgaagacg ggagccaacc gccgccgccg gagccgaaag     1980

gggacgccac gccggaaggg gagaaagcga ccgagaagga gaacggcgau aaaagcgaag     2040

cgcaaaagcc gucggaaaaa gccgaagccg gcccggaagg gguggccccg gcgccggaag     2100

gggaaaaaaa acaaaaaccg gcgcgcaaaa gaaggauggu cgaagaaaua ggcgucgaau     2160

uagucgucuu agauuuaccg gaucucccgg aagacaaauu agcccaaagc guccaaaagu     2220

ugcaagaucu caccuugagg gauuuagaaa aacaagagag agagaaggcc gcaaauucgc     2280

ucgaggccuu uaucuucgaa acgcaagaua aauuauauca accggaauau caagagguca     2340

guaccgaaga acaaagggaa gaaauaagcg gcaaauuguc ggcggccagu acgugguuag     2400

aagacgaagg ggucggggcg acgaccguca ugcucaaaga aaaauuagcc gaauuacgca     2460

aauuauguca gggcuuauuc uucagagucg aagaaaggaa aaaauggccg gagagauuaa     2520

gcgcguugga caacuuguug aaucacaguu cgauguuuuu gaaaggcgcg agauugauac     2580

cggaaaugga ucaaauauuu accgaagucg aaaugaccac ccucgaaaag gugauaaacg     2640

aaacgugggc guggaaaaac gccaccuuag cggaacaagc caaauuaccg gcgaccgaaa     2700

aaccgguccu cuugagcaag gauaucgagg ccaaaaugau ggcguuagau agggaagucc     2760

aauacuuauu gaacaaagcg aaauucacga aaccgagacc gagaccgaaa gauaaaaacg     2820

gcacgagagc cgaaccgccg uugaacgcgu cggcgucgga ucaaggcgaa aaagugauac     2880

cgccggccgg gcaaaccgag gacgccgaac cgaucagcga gccggaaaag gucgaaaccg     2940

ggagugaacc gggggauacc gaaccgcucg aacucggggg gccgggggcc gagccggagc     3000

aaaaggagca gagcaccggg caaaaaagac cgcucaaaaa ugaugaguug ugaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  5715
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt10)

<400>  5715
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgg       60

aggagacgca aacgcaggau cagccgaugg aggaagagga gguagagaca uucgcauucc      120

aggcggagau agcacaauua augucguuaa uaauuaacac guucuacagu aacaaggaga      180

uauucuuaag ggaguuaaua ucgaacucgu cggacgcguu ggacaaaaua cgauacgaau      240

cguuaacgga cccgucgaag uuagacucgg guaaggaguu gcacaucaac uuaauuccga      300

acaagcagga ccggacguua acgauaguag acacggguau aggaaugacg aaagcggacu      360

ugauaaacaa cuuaggaacg auagcgaagu cggguacuaa ggcguucaug gaggcauuac      420

aggcgggugc ggacauaagu augauagguc aauucggggu cggauucuac ucggcauacu      480

uagucgcaga gaagguaacg guaaucacga agcacaacga cgacgaacaa uacgccuggg      540

agaguucggc gggugguagu uucacgguac gcacugacac gggugagccg auggguaggg      600

guacgaaggu aauauuacac uuaaaggagg accagacgga auacuuagag gagcgccgga      660

ucaaggagau uguuaaaaag cacucgcaau ucaucggcua cccuauaacg uuauucgucg      720

agaaggagcg cgacaaggag guuagugacg acgaggcgga ggagaaagag gacaaggagg      780

aggagaagga aaaggaggag aaggagucgg aggacaagcc ggagauagag gacguaggau      840

cggacgagga ggaggagaag aaggacgggg acaaaaagaa gaagaaaaag auaaaggaga      900

aauacauaga ccaagaggag uuaaacaaga cgaagccgau cuggacaagg aacccggacg      960

acauaacgaa cgaggaguac ggugaguucu acaagucguu aacaaacgac ugggaggacc     1020

acuuagcggu caaacacuuc aguguagagg ggcaguuaga guuccgcgcg uuguuauucg     1080

uaccgaggcg cgcgccguuc gacuuauucg agaaccggaa gaagaaaaac aauauaaagu     1140

uauacguccg aaggguauuc auaauggaca acugcgagga guuaauuccg gaguaccuca     1200

acuucauacg cggugucguc gacucggaag acuugccguu aaacaucucg cgagagaugu     1260

uacagcaguc gaagaucuua aagguaauac gcaagaacuu agucaagaag ugcuuagagu     1320

uauucacgga guuggcagag gacaaggaga auuacaaaaa auucuacgag caguucucga     1380

agaauauaaa guuagggaua cacgaggaca gucagaaccg aaaaaaguua ucagaauuau     1440

uacgauacua uacgagugcg ucgggggacg aaauggucag uuugaaggac uauuguacac     1500

ggaugaagga aaaccaaaag cacauauacu acauaacggg ggagacgaag gaccaaguug     1560

cgaacucggc auucgucgag cgcuuacgga agcacggguu agaggucaua uacaugaucg     1620

aaccuauaga cgaguauugc guacagcaau ugaaggaguu cgaggggaag acauuaguaa     1680

guguaacaaa ggagggguua gaguugccgg aggacgagga ggagaagaag aagcaggagg     1740

agaagaagac gaaguucgag aacuuaugca agauaaugaa ggacauauua gagaagaagg     1800

ucgagaaggu cgucgucucu aacagguugg uaacgucgcc gugcugcaua guaacgucga     1860

cuuacgguug gacugcgaac auggaacgaa uaaugaaggc gcaggcguua agggacaaca     1920

guacgauggg uuacauggcg gcaaagaagc auuuagaaau caacccggac cacucgauca     1980

uagagacguu acgacagaag gcggaggcgg acaagaacga caagaguguc aaagacuuag     2040

uaauauuauu auacgagacg gcguuguuau cgaguggguu cucguuagag gacccacaaa     2100

cucacgcgaa ccgaauauau cgcaugauaa aguugggauu aggaaucgac gaggacgacc     2160

cgacggcgga cgacacaucg gcggccguaa ccgaggagau gccgccguua gagggugacg     2220

acgauacuuc gcggauggag gagguagacu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  5716
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt10)

<400>  5716
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgg       60

aggaggucca ucauggcgag gaagaggugg agacguuugc guuucaagcg gaaaucgcgc      120

aguugauguc gcucauaauc aauacguuuu auaguaauaa ggagauauuu uugcgcgaac      180

ucaucagcaa ugccucggau gcguuagaua aaauccgcua ugagucguug accgauccga      240

gcaaguuaga uagcgggaaa gaacucaaga ucgauauaau accgaauccg caggagagga      300

ccuugacguu ggucgauacg gggaucggga ugaccaaggc ggauuugauc aauaacuugg      360

ggaccaucgc gaaaucgggc accaaggcgu uuauggaagc guugcaggcc ggggcggaua      420

ucucgaugau agggcaguuu ggggucgggu uuuauucggc cuauuuggug gcggagaaag      480

ucgucgucau aaccaagcau aaugaugaug agcaguaugc gugggagucg ucggcggggg      540

gcucguuuac cgugcgcgcc gaucaugggg agccgaucgg gaggggcacc aaggucauau      600

ugcauuugaa agaggaucag acggaguauc ucgaggaaag gcgcgugaaa gaggugguga      660

agaagcauuc gcaauuuaua ggguauccga ucacguugua uuuagagaag gaacgcgaga      720

aagagaucuc ggaugaugaa gcggaagagg agaaggggga gaaggaggag gaggauaagg      780

augaugagga gaaaccgaaa auagaggaug ucgggucgga ugaggaggau gauagcggga      840

aagauaaaaa gaagaagacc aagaagauaa aggaaaagua uauagaucag gaggaauuaa      900

auaagaccaa gccgauaugg acgcgcaauc cggacgauau aacccaggag gaguauggcg      960

aguuuuauaa gagcuugacc aaugauuggg aagaucauuu ggccgucaaa cauuuuucgg     1020

ucgaggggca guuggaguuu cgcgccuugu uguuuauacc gcgccgcgcc ccguuugauu     1080

uauuugagaa uaaaaagaag aagaauaaua ucaaauugua ugugaggagg guguuuauca     1140

uggauagcug ugaugaguua auaccggagu auuugaauuu uauaagaggg gucgucgaua     1200

gugaggauuu gccguugaau auaucgaggg agauguugca gcaaucgaaa aucuuaaagg     1260

ucauacgcaa gaauauaguc aagaaauguu uggaguuguu uucggagcuc gccgaagaca     1320

aggagaauua uaaaaaguuu uaugaggcgu uuucgaaaaa uuugaaguua gggauccaug     1380

aggauucgac gaacaggcgc agguugucgg aguuguugcg cuaucauacc ucgcaaucgg     1440

gggaugaaau gaccucguug agugaguaug ucucgagaau gaaggagacc cagaaaagca     1500

ucuauuauau aacgggggaa ucgaaagagc aggucgccaa uagcgccuuu guggagaggg     1560

ucaggaaaag gggguuugag guggucuaua ugaccgaacc gauagaugaa uauugcgucc     1620

agcaauugaa ggaguuugau gggaagucgu uggugagcgu cacgaaggag ggguuggagc     1680

ucccggagga ugaggaggaa aaaaagaaga uggaggagag caaggcgaag uuugaaaauc     1740

ucuguaaauu aaugaaggaa auauuggaua agaaagucga gaaagugacc auaagcaaua     1800

gauuagucuc gagcccgugu uguauaguga ccucgaccua uggguggacc gccaauaugg     1860

agaggaucau gaaggcccag gcguugcgcg auaauagcac gaugggcuau augauggcga     1920

aaaagcauuu ggagaucaau ccggaucauc cgaucgucga gaccuugcgc cagaaagcgg     1980

aggccgauaa gaaugauaag gcggucaagg auuuggucgu guuauuguuu gagaccgcgu     2040

uguugagcuc gggguucagc uuagaagauc cgcagacgca uucgaaucgc auauauagga     2100

ugaucaaauu gggguuaggg aucgaugaag augaggucgc ggccgaggaa ccgaaugccg     2160

ccgugccgga ugagauaccc ccguuagagg gcgaugaaga ugccagccgc auggaggaag     2220

uggauugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  5717
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt10)

<400>  5717
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcgcg       60

cguugugggu cuuggguuug uguugugucu uguugacauu ugggagcgug agggccgaug      120

augaagugga uguagauggg accguggagg aagauuuggg gaagucgagg gaggggucga      180

gaaccgacga ugaaguggua caaagggaag aggaagccau ccaauuggac ggguugaaug      240

cgucgcaaau cagggaauug agagaaaaau cggagaaauu cgcguuucag gcggagguga      300

aucgcaugau gaaguugauu auaaauaguu uguauaagaa caaggaaauc uuuuuaagag      360

aguugauaag uaaugcgucg gacgcgcucg acaaaaucag guugauaucg uuaaccgaug      420

agaacgcgcu cucgggcaau gaagaguuga cggucaagau caaaugugau aaagaaaaaa      480

auuuauugca cgucaccgau acaggggucg ggaugacgag ggaggaauug gugaagaauu      540

uggggacgau cgcgaaaucg gggaccucgg aauuuuugaa uaagaugacc gaagcgcaag      600

aggaugggca aagcaccucg gaauugaucg ggcaauuugg cgucggcuuu uauucggccu      660

uuuuggucgc cgauaaaguc aucgugaccu cgaagcauaa uaaugacacg caacauauuu      720

gggaaagcga uucgaaugag uucucgguca uagccgaucc cagagggaau accuuggggc      780

gcgggacgac gauaaccuug gucuugaaag aggaagccag cgauuauuug gaguuagaua      840

ccauaaagaa uuuggucaaa aaguacucgc aauuuauuaa uuuucccauc uauguguggu      900

cgagcaaaac cgagaccguc gaagaaccua uggaagaaga agaagccgcg aaggaggaaa      960

aggaggagag cgacgaugag gccgccgugg aagaggagga agaggaaaag aaaccgaaaa     1020

cgaaaaaggu cgaaaagacg gucugggauu gggaguugau gaacgauauu aagccgaucu     1080

ggcaaaggcc cucgaaggag guggaagagg augaauauaa ggcguuuuau aaaucguuuu     1140

cgaaagaguc ggacgauccu auggcguaca uccauuucac cgcggagggg gaagucaccu     1200

uuaagucgau auuguuugug ccuaccucgg cgccgcgcgg guuguucgau gaguauggcu     1260

cgaaaaaauc ggauuauaua aaguuguaug uaaggagagu cuuuauuacg gaugauuuuc     1320

augauaugau gccgaaauau uuaaauuucg ugaaaggggu cgucgacagc gacgauuuac     1380

cguugaacgu cucgcgcgaa accuugcaac aacauaaguu auugaaaguc aucaggaaaa     1440

aauuggugcg caagaccuug gauaugauaa aaaaaaucgc cgacgacaaa uauaacgaua     1500

ccuuuuggaa ggaauuuggg acaaauauua aguugggggu cauagaggau cauucgaaca     1560

ggacccgcuu ggccaaguug uugcgcuuuc aaucgucgca ccauccgacc gauaucaccu     1620

cguuagauca auacgucgag aggaugaaag agaagcaaga uaagauauau uuuauggccg     1680

ggaguucgag gaaggaagcc gagucgucgc cguucgucga aagguuguug aaaaaagggu     1740

acgaggugau auaucucacg gagccggucg augaguauug uauacaagcg uugccggaau     1800

uugaugggaa acgcuuucaa aacguggcca aagagggggu caaauuugau gagucggaaa     1860

aaaccaaaga aagccgcgag gccguggaaa aggaauuuga accguuauug aauuggauga     1920

aggauaaggc auugaaagau aaaaucgaga aagccgucgu cagccaaaga uuaacggaau     1980

cgccgugcgc guugguggca ucgcaauaug gguggucggg uaauauggaa cgcauaauga     2040

aagcccaagc guaucaaacc gggaaagaua uaucgacgaa uuauuaugcg ucgcaaaaaa     2100

aaaccuuuga gauaaauccg cgccaucccu ugauucgcga uauguugagg cgcauaaaag     2160

aggaugaaga cgauaaaacg gucuuggauu uggcaguagu cuuguuugag accgcgaccu     2220

ugcgcucggg guauuuauug ccggauacca aggcguaugg ggauaggaua gagaggaugu     2280

ugcgcuuguc guugaauauc gauccggacg ccaaagucga ggaagaaccg gaagaagaac     2340

cggaggaaac cgccgaagau acgacggaag auaccgaaca agaugaagac gaagaaaugg     2400

acguagggac cgaugaggaa gaggagacgg ccaaagagag cacggccgag aaagaugagu     2460

ugugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  5718
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt10)

<400>  5718
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcga       60

gggagcucag ggcguuguug uuguggggga ggagguugag gccguuguug agggcgccgg      120

ccuuggcggc cgugccgggg gggaagccga ucuugugucc gaggcgcacc accgcccagu      180

uggggccgag gaggaauccg gcguggagcu ugcaagcggg gagguuguuu aguacccaga      240

cggcggagga uaaggaggag ccguugcauu cgaucauauc gucgacggaa aguguccagg      300

ggucgacgag uaagcaugaa uuucaagcgg agacgaaaaa guuguuggau auagucgcga      360

ggucguugua uagugagaag gagguguuua uaagggaguu gauaagcaau gccagugaug      420

ccuuggagaa guugaggcau aaguugguca gcgaugggca ggccuugccg gagauggaga      480

uccacuugca gacgaaugcc gagaagggga cgaucaccau ccaggauacc gggaucggga      540

ugacccaaga agaguuggug agcaauuugg ggaccaucgc gaggucgggg ucgaaggcgu      600

uuuuggaugc guugcagaau caggcggagg cgaguaguaa gauaauaggg caauuugggg      660

ucggguuuua cagugcguuu auggucgccg auagggugga ggucuacagc aggagcgccg      720

cgccggggag uuugggguau cagugguuga gugauggguc gggggucuuu gagaucgccg      780

aggcgagcgg ggugaggacc gggacgaaga uaauaaucca uuugaagucg gauuguaagg      840

aguucucgag cgaggcgagg gugagggaug uggugacgaa guacagcaac uuugugagcu      900

ucccguugua cuugaauggg cgcaggauga auaccuugca ggcgauaugg augauggauc      960

cgaaggaugu gagggagugg caacacgagg aauuuuauag guaugucgcc caggcccaug     1020

auaagccgag guauacguug cauuauaaga ccgaugcgcc guugaauaua aggaguauau     1080

uuuauguccc cgauaugaag ccgucgaugu uugaugucag uagggaguug gggagcagcg     1140

ucgccuugua uagccgcaag guguugaucc agaccaaggc gacggauaua uugccgaagu     1200

gguugagguu uauacgcggg gugguggauu cggaggauau accguugaau uugagcaggg     1260

aguuguugca ggagagugcg cucauaagga aguugaggga ugucuugcag caaagguuga     1320

ucaaguuuuu uauagaccag aguaaaaagg acgccgagaa guaugcgaag uuuuuugagg     1380

auuauggguu guuuaugaga gaggggauag ucaccgccac ggaacaggaa gugaaggaag     1440

auaucgccaa guuguugcgc uaugaaaguu cggcguugcc gagcgggcag uugaccucgu     1500

ugucggagua ugcgagcagg augcgcgccg ggacgaggaa uauauauuau uugugugcgc     1560

cgaauaggca uuuggccgag cauagcccgu auuaugaagc gaugaagaaa aaggauacgg     1620

agguguuauu uuguuucgag caguuugaug aguuaacguu guugcauuug cgcgaauuug     1680

auaagaaaaa guugauaucg guggaaaccg auauaguggu cgaucauuau aaggaggaga     1740

aguuugaaga uaggucgccg gcggccgagu guuugagcga gaaggagacg gaggaguuga     1800

uggcguggau gagaaaugug uuggggaguc gcgucacgaa ugucaaggug accuugcgcu     1860

uggauacgca uccggcgaug gugacggucu uggagauggg ggccgcgagg cauuuuuuga     1920

ggaugcagca guuggccaag acccaagaag agagggcgca guuguugcag ccgacguugg     1980

agaucaaucc gaggcaugcg uugaucaaaa aguugaacca guuacgcgcg agugaaccgg     2040

gguuggcgca guuguuggug gaucaaauau augagaaugc gaugauagcc gccggguugg     2100

ucgaugaucc gagggcgaug gucgggaggu ugaacgaguu guuggugaag gccuuggaaa     2160

ggcacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  5719
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt10)

<400>  5719
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggua       60

agaucucguc auuaccgacg caguuguuca agugcugcuu cugcgacuuc uuaaagguaa      120

agaugcacac gaugucgagu ucccacuuau ucuacuuggc cuuaugcuug uugacguuca      180

ccuccucggc gaccgcaggg ccggagaccu ugugcggcgc ggaguuagua gacgcguuac      240

aguucgucug cggugaccga gguuucuacu ucaacaagcc gacggguuac ggguccucgu      300

cgcgccgugc accgcagacg ggcaucguug acgaaugcug cuuccguucu ugcgaccucc      360

gucgcuuaga gauguacugc gcgccguuga agccggcgaa gucggcccgu ucgguacgcg      420

cgcagcggca cacggacaug ccaaagacgc agaaagaggu ccacuuaaag aacgcgucgc      480

guggaucggc cggcaacaag aacuaccgga ugugaggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  5720
<211>  925
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt10)

<400>  5720
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggca       60

uacccauggg uaagucaaug uugguguuau uaaccuucuu agccuucgcc ucgugcugca      120

ucgcggccua ccguccguca gagacccuau gcggcgggga gcuaguagac acgcuacagu      180

ucgugugcgg cgaccggggg uucuacuucu cgcgccccgc gucgcgcgug ucccgccguu      240

cgcgcggcau cguagaggag ugcugcuucc gaucaugcga cuuggccuua uuagagaccu      300

acugcgccac cccggccaag ucggagcgag acgugucgac gccgccgacc guguuaccgg      360

acaacuuccc ccgguacccc gucggcaagu ucuuccagua cgacacgugg aagcagucga      420

cucagagacu ucgucgcggg uuaccggcgu uguugcgugc ccgacgaggc cacgugcuag      480

ccaaggaguu agaggcguuc cgcgaggcga agcggcaccg cccguuaauc gcguuaccca      540

cucaggaccc cgcgcacgga ggcgccccgc ccgagauggc gucgaaccga aagugaggac      600

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      660

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      720

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      780

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      900

ggcucuuuuc agagccacca gaauu                                            925


<210>  5721
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt10)

<400>  5721
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

cguucaguac gucggcguuc ggccccgucg cguucucguu agguuuguua uuggucuuac      120

cggcggcguu cccagcgccc guuccaccgg gugaggacuc gaaggacguu gcggcgcccc      180

accgacagcc cuugaccucg uccgagcgua ucgacaagca gauccgauac aucuuagacg      240

guauaagugc guuacgcaag gagacgugca acaaaucgaa caugugcgag aguucgaagg      300

aggcguuagc cgagaacaac cucaacuugc cgaagauggc ggagaaggac gggugcuucc      360

agaguggguu caacgaggag acaugcuuag uaaagaucau aacgggccuc cuugaguucg      420

aggucuaccu cgaguacuua cagaacaggu ucgagucauc ggaggagcag gcacgcgcgg      480

uucaaauguc gacgaaggua uugauccagu uccuccagaa gaaggccaag aacuuagacg      540

cgaucacgac gccggacccg acuaccaacg cgaguuuguu aacuaaguua caggcgcaga      600

accagugguu gcaggacaug accacccacu ugaucuugcg gucguucaag gaguucuugc      660

agaguucuuu aagagcguua aggcagaugu gaggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  5722
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt10)

<400>  5722
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgu       60

uauugugguu aaggggguuc uuguuagcgu cgugcuggau caucgugcgu ucgucgccga      120

cgcccggguc ggagggucac ucggccgcac cggacugccc aaguugcgca cuugccgcgu      180

uaccgaagga cguuccgaac ucgcagccgg agaugguuga ggccgugaaa aagcacauau      240

ugaacauguu acaccuaaag aagcgaccgg acguaacgca gccggucccc aaagcggccc      300

uauuaaacgc uauacggaag uuacacguug ggaagguagg cgagaacggu uacguggaga      360

ucgaggacga caucgggcgc cgcgccgaga ugaacgaguu aauggagcag acgucagaga      420

ucaucaccuu cgcggagucg ggcacugcgc guaagacuuu gcacuucgag aucucgaagg      480

aggguucgga cuuaucggug guagagcggg ccgaggugug guuauucuug aaggugccga      540

aggcgaaccg aacgcgaacc aaggucacca uccgauuguu ccagcaacag aaacaccccc      600

aggggaguuu agacaccggg gaggaggccg aggagguagg ucucaagggg gagcgauccg      660

agcuccucuu aucggagaag guggucgacg cgcgaaaguc uacguggcac guauucccgg      720

ugucgucguc gauccagcgc cuacuugacc agggcaagag uucguuggac guccgcauag      780

cgugcgagca gugccaggag ucgggcgcgu cucuuguauu guuagggaag aagaagaaga      840

aggaggagga gggugagggg aagaagaagg ggggcgggga gggcggggcg ggcgcggacg      900

aggagaagga gcagucucac cggccguucu uaauguuaca agcgcgucaa ucggaggacc      960

acccgcaccg acgacgccga cguggguuag agugcgacgg caaggugaac aucugcugca     1020

agaagcaguu cuucguuuca uucaaggaca ucgguuggaa cgacuggaua auagccccgu     1080

cgggguacca cgcgaacuac ugcgagggcg agugcccguc ccacaucgcc gguacuucgg     1140

gcucgucguu aucguuccac aguacgguua uaaaccauua ccguaugcgu ggacacuccc     1200

ccuucgcgaa cuugaagagu ugcugcgugc cgaccaaguu gcgucccaug ucgaugcuuu     1260

acuacgacga cggccagaac auuauaaaga aggacaucca gaacaugauc gucgaggaau     1320

gcggcugcag uugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  5723
<211>  1606
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt10)

<400>  5723
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggacg       60

guuuaccggg acgagcuuug ggugcggcuu guuuguuauu guuggcagcg gguugguuag      120

gcccggaagc guggggaucg ccgacaccuc ccccuacucc ggcggcgcca ccgcccccgc      180

caccgccggg gucgccaggc gggucccaag auacuugcac aaguugcggg gguuuccgac      240

gacccgagga auugggacgc guagacggug auuucuugga agcuguaaag cgucauaucu      300

uaucgcguuu acagaugcga gggcgaccga acauaaccca cgccguaccg aaggcggcga      360

ugguuaccgc guuacgaaag uuacaugcug ggaagguucg ugaggacggg cguguagaga      420

ucccccauuu ggacgggcac gccucgccag gggccgacgg gcaagagcga gucucggaga      480

uaauuaguuu cgcggagacu gacggguuag cgucgucgag gguacguuua uacuucuuca      540

uaucgaacga ggguaaccaa aacuuguucg uaguacaggc gaguuuaugg uuauaccuua      600

agcuauuacc auacguuuua gagaaggggu cgcgucgaaa aguaagggua aagguauacu      660

uccaagagca aggucacggc gaccgaugga acaugguaga gaagcggguu gaccuuaagc      720

gaaguggaug gcacacguuc ccguuaacug aggcaauaca ggcauuauuc gagcguggag      780

agcgccgcuu aaacuuagac guacaaugcg acucgugcca ggaguuggca gucgucccag      840

uauucguaga ccccggggag gagagucauc gaccguucgu aguaguacag gcgcgcuuag      900

gugacucgcg acaccgaauc cggaagcgug guuuagagug cgacgguagg acgaacuugu      960

gcugccgaca gcaguuuuuu auagacuuua gguugaucgg guggaacgac uggauaauug     1020

cgccgacagg auacuacggu aacuauugcg aaggaaguug cccggcguac uuagcggggg     1080

ugccagguuc ggcaucgucg uuccacacug cgguaguuaa ccaguaccga augcgaggau     1140

ugaauccggg gacaguaaac ucgugcugca ucccgacgaa guuaaguacg augucgaugu     1200

uauacuucga cgacgaguac aacauaguaa agcgcgacgu cccgaacaug aucguagaag     1260

agugcgguug cgcgugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1320

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1380

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1440

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1560

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1606


<210>  5724
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt10)

<400>  5724
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcgu       60

ugaggguccu cuuauugacc gccuugaccu uaugccaugg guuuaauuug gauacggaga      120

acgccaugac guuucaggag aaugccaggg gguuugggca gagcgucgug caguugcagg      180

ggagcagggu cguggugggg gcgccgcagg aaaucguggc cgccaaucag agggggagcu      240

uguaucagug ugauuauagc acgggcagcu gugagccgau acgcuuacag gugccggugg      300

aggccgugaa uaugucguua ggguugucgu uggcggcgac cacgagcccg ccgcaguugc      360

ucgccugugg gccgacggug caccaaacgu guagcgagaa uacguauguc aagggguugu      420

guuucuuguu cggcaguaau uugaggcaac aaccgcagaa guuuccggag gcguugaggg      480

ggugccccca ggaggauucg gauaucgcgu ucuugaucga ugggaguggg aguaucaucc      540

cgcaugauuu uaggagaaug aaagaguucg ugagcaccgu cauggagcag uugaaaaaga      600

guaagaccuu guuuaguuua augcaguauu cggaagaauu ucgcauacau uuuacguuua      660

aggaauuuca aaauaauccg aauccgagga gcuuagucaa gccgaucacc caguuguugg      720

ggcgcaccca uaccgcgacc gggauacgca aaguggucag ggaguuguuu aauaucacca      780

acggggccag gaagaaugcg uuuaagauau uggucgugau cacggauggg gagaaguuug      840

gcgauccgcu cggguaugag gaugucauac cggaggccga ucgcgaaggg gucauaaggu      900

augugauagg ggucggcgau gcguuuaggu cggagaagag uaggcaagag uugaauacca      960

ucgcgaguaa gcccccgagg gaucaugugu uucaggugaa uaauuuugag gcguugaaga     1020

cgauacagaa ucaguugagg gaaaagaucu uugcgaucga ggggacgcag acggggucga     1080

guucgaguuu ugagcacgag augagucagg agggguuuuc ggcggccaua acgaguaaug     1140

ggccguuguu gagcacggug gggagcuaug auugggccgg ggggguguuu uuguauacga     1200

guaaagagaa gaguaccuuu auaaauauga cgcgcgugga cagcgauaug aaugaugccu     1260

acuuggggua ugcggccgcc auaaucuuga ggaaucgcgu ccagagcuug guccucgggg     1320

cgccgaggua ucagcauaua ggguuggucg ccauguuuag gcagaauacg ggcauguggg     1380

agucgaaugc caaugugaaa gggacgcaga uaggggccua uuuuggggcc agcuugugua     1440

gcgucgaugu ggauagcaau gggucgaccg acuuggucuu gauaggggcc ccgcauuauu     1500

acgaacaaac cagggggggg caggucagcg ugugcccguu gccgaggggg agggcgaggu     1560

ggcaguguga ugccgucuug uacggggagc aggggcagcc gugggggcgc uuuggggcgg     1620

ccuugacggu guugggggau gugaaugggg auaaguugac ggaugucgcc auaggggccc     1680

cgggggaaga ggauaauagg ggggccgucu auuuguuuca ugggacgagu gggucgggga     1740

uaagcccgag ucauagccag aggaucgcgg ggagcaaguu aaguccgcgc uuacaguauu     1800

uuggccaguc guugaguggg gggcaggauu ugaccaugga uggguugguc gacuuaaccg     1860

ucggggccca gggccacguc uuguuguuga ggagucagcc ggucuugagg gugaaagcca     1920

uaauggaauu uaacccgaga gagguggcca ggaauguguu ugaguguaau gaucaggucg     1980

ugaaagggaa ggaggcgggg gaggugcgcg ucugcuuaca uguccagaaa ucgaccaggg     2040

acagguuaag ggaggggcag auacaaagug ucgugacgua ugauuuggcg uuggauagug     2100

ggcgcccgca uucgagggcg guguuuaaug agacgaagaa cagcacgagg agacagacgc     2160

aagucuuggg guugacgcag accugugaaa ccuugaaguu gcaguuaccg aauugcauag     2220

aggauccggu gagcccgaua gucuugaggu ugaacuucag uuuggugggg accccguuga     2280

gcgccuuugg gaauuugagg ccgguguugg cggaggaugc gcagagguug uuuacggcgu     2340

uguuuccguu ugagaaaaau ugugggaaug auaauaucug ccaggaugau uugucgauaa     2400

cguuuagcuu uaugagcuug gauuguuugg ucgucggggg gccgagggag uucaauguga     2460

ccgugacggu ccgcaaugau ggggaagaca guuaucgcac ccaggucacc uuuuuuuuuc     2520

ccuuggauuu gagcuauagg aaggugagca cguugcagaa ucagaggagc cagaggagcu     2580

ggcgcuuggc cugcgagagc gcgagcagca ccgaggucuc gggggcguua aagagcacga     2640

guugcaguau caaucauccg auauuuccgg aaaauucgga ggugaccuuu aauaucaccu     2700

uugaugucga uagcaaggcc agcuugggga auaaguugcu cuuaaaggcg aaugugacgu     2760

cggagaauaa uaugccgcgc accaauaaga ccgaauuuca guuggaguug ccggugaaau     2820

acgcggucua uaugguggug acgucgcaug gggucaguac caaguauuug aauuucacgg     2880

cgucggagaa uaccagucgc gucaugcagc aucaguauca agucaguaau uuggggcaga     2940

ggucguugcc gauaaguuug gucuuuuugg ucccggugcg cuugaaucaa accgucaucu     3000

gggauaggcc gcaggucacc uuuagcgaga auuugaguag uaccugccau accaaggaga     3060

gguugccguc gcacagugau uucuuggccg aauugaggaa ggcgccgguc gucaauugua     3120

gcauagccgu cugucaaagg auccaaugug auaucccguu uuucggcauc caagaggaau     3180

uuaaugccac cuugaagggg aauuugucgu uugauuggua cauaaaaacg agccacaauc     3240

auuuguugau cgucaguacc gcggagauau uguuuaauga uucgguguuu acccucuuac     3300

cggggcaggg ggccuuuguc aggagccaaa ccgagaccaa ggucgagccg uuugaggugc     3360

ccaaucccuu gcccuugaua guggggagua gugucggggg cuuguuguug uuggcguuga     3420

uaaccgccgc cuuauacaaa uugggguuuu uuaaaaggca guauaaggac augaugagug     3480

agggggggcc cccgggcgcg gagccgcaau gaggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  5725
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt10)

<400>  5725
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguuua       60

guuuaaaaac cuugccguuc uuauugcucu ugcacgucca aaucaguaaa gcguucccgg      120

ucagcagcaa ggaaaagaac accaagaccg uccaagauua uuuagagaaa uuuuaucagc      180

ucccgucgaa ucaauaccaa agcacccgca aaaacgggac caacgucaua gucgagaaau      240

ugaaggagau gcaaagguuc uucggccuca acgucaccgg caaaccgaac gaagagaccu      300

uagauaugau gaagaaaccg aggugcgggg ucccggauuc ggggggguuc augcucacgc      360

cggggaaucc gaaaugggag aggaccaauc ucacguaucg caucaggaau uacacgccgc      420

aauuaagcga agccgaaguc gagcgcgcca uaaaagacgc guucgaguug uggucggucg      480

ccagcccguu gauauuuacg cgcauaagcc aaggggaagc cgacauaaau aucgccuucu      540

aucagcgcga ccauggggau aacagcccgu ucgacgggcc gaacgggaua uuggcccacg      600

cguuccaacc ggggcagggg aucggggggg acgcccacuu cgacgcggag gagaccugga      660

cgaauacgag ugccaacuau aaucucuucu uggucgccgc ccacgaguuc gggcacagcc      720

ucggcuuggc ccauaguagc gauccggggg cgcucaugua cccgaauuac gccuuucgcg      780

agacgucgaa uuauagcuug ccgcaggacg auauagacgg gauccaagcg auauacgggu      840

ugagcucgaa uccgauacag ccgaccgggc cgucgacccc gaagccgugc gauccgucgc      900

ucaccuucga cgccauaacg accuugaggg gggagaucuu guuuuucaag gaucgcuauu      960

uuuggcgccg ccacccgcaa uugcagcgcg uggagaugaa cuucaucagc uuguuuuggc     1020

cgaguuugcc gaccgggauc caagccgccu acgaggacuu cgaucgcgau uugaucuuuu     1080

uguucaaggg gaaucaguau ugggccuuau cgggguacga caucuuacag ggguacccga     1140

aagacaucag caauuacggg uuuccgucgu cggugcaggc caucgaugcc gccgucuuuu     1200

aucgcucgaa gaccuauuuu uucgucaacg aucaguuuug gcgcuacgac aaucagcgcc     1260

aguuuaugga accgggguac ccgaagucga ucagcggggc guucccgggg aucgaaucga     1320

aggucgacgc cgucuuucaa caggagcacu uuuuucacgu guuuucgggg ccgcgcuacu     1380

augccuucga cuugaucgcc caacgcguca cgcgcgucgc ccgcgggaac aagugguuga     1440

auugccgcua cgggugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  5726
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt10)

<400>  5726
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucgu       60

uauggcaacc uuugguauug guauuauugg ucuuagggug cugcuucgca gcgccgcguc      120

agcgacaguc gacauuaguc uuguucccgg gugacuuacg aaccaacuua acugaucggc      180

aauuagcuga agaguauuua uacagguacg gcuacacgcg cguagcggag augagggggg      240

agucuaagag uuuaggccca gcauuacucu uguugcagaa acaguuaucg uuacccgaaa      300

cgggggaauu agacucggcg acacucaagg cgaugcgcac uccucguugc ggaguacccg      360

acuugggacg auuucagaca uucgagggug auuugaagug gcaccaccac aacauaacgu      420

acuggaucca gaacuacucu gaggacuuac cucgugcagu aauagacgac gcuuucgcac      480

gagcguucgc uuuauggucg gccguuacac ccuugacguu uacgcgaguc uauucgcgcg      540

acgccgacau aguaauacag uucgggguag ccgagcacgg ugacggcuac ccauucgacg      600

guaaggacgg uuuauuagcg cacgcguucc cgccggggcc ggguauccag ggcgacgcgc      660

acuucgacga cgacgaauua uggucuuuag ggaaaggggu aguuguaccu acgcguuucg      720

guaacgcgga cggugccgca ugccauuucc cguucauauu cgaggggcga ucauauagug      780

cgugcacuac ggacggacgg ucggacgggu uacccuggug uucgacuacu gcgaacuacg      840

acacggacga ccgauucggu uucugcccgu cggagcguuu auacacgcaa gacgguaacg      900

cggacggcaa gccuugccag uucccuuuca uauuccaggg acagucguac ucggcaugca      960

caaccgacgg gcggucggac ggguaccggu ggugcgcgac uacggcgaac uacgaucgcg     1020

acaaguuauu cggguucugc ccaacacggg cagacucuac cguaauggga gggaacagug     1080

ccggagaguu gugcguauuc cccuucacgu ucuugggaaa agaguacuca acaugcacuu     1140

cggaaggccg gggugacggu cgauuguggu gcgccacuac gaguaacuuc gacucggaca     1200

aaaagugggg uuucuguccu gaccagggcu auucguuauu cuuaguagca gcacacgagu     1260

ucgggcacgc auuaggauug gaccacagua guguacccga agcauugaug uauccgaugu     1320

accgauuuac ggaagguccg ccguuacaca aggacgacgu aaacgguauc cgacacuuau     1380

acggcccacg gccggagccg gaaccgcgcc caccgaccac aacgacucca cagcccacug     1440

caccgcccac aguauguccu acggguccuc cgacaguaca cccgucggag cgaccgacgg     1500

caggucccac uggaccgccg agugcagggc cgacggggcc gccgaccgca gguccgucga     1560

cggcgacaac ggucccguua ucgcccguag acgacgcgug caacguuaac auauucgacg     1620

caauagcaga gauagguaac caguuauacu uauucaagga cggcaaguac uggcgcuuuu     1680

cggaggggcg aggaagucga ccccaggggc cguucuuaau cgcggacaag uggccggcau     1740

uaccucgaaa guuagauuca guauucgagg agcgauuaag uaagaaauua uucuucuucu     1800

cggguaggca aguaugggua uauacgggug ccuccguauu agggccccgg aggcucgaca     1860

aguuggggcu cggugcugac gucgcgcagg uaacgggugc uuuacgcucg ggucgaggaa     1920

agauguuauu auucaguggu cgccgauuau ggcguuucga cguaaaggca cagauggucg     1980

acccucgauc ggcgucggag gucgaccgua uguucccggg uguaccguua gacacacacg     2040

acguauucca guaccgcgaa aaggcuuacu ucugccagga uagguucuac uggcgagucu     2100

cgucgagguc ggaauuaaau caaguagacc agguagggua ugucacguac gacaucuuac     2160

agugcccgga ggacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  5727
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt10)

<400>  5727
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

cgggcguguu agccgcguuu uuguuucucu cguggaccca cugcagagcg uuaccguugc      120

cgucgggggg ggacgaggac gaccucagcg aagaggauuu gcaauucgcc gaaagguauu      180

uacgcagcua uuaucacccg accaacuugg ccgggauauu aaaagaaaac gccgccucga      240

guaugaccga acgcuugagg gagaugcaaa guuuuuuugg gcucgaaguc accgggaagu      300

uggaugacaa uacgcucgac gugaugaaga aaccgcgcug uggcgucccg gacgucgggg      360

aguauaacgu cuuuccgagg accuugaagu ggaguaagau gaaccucacg uaucgcaucg      420

ucaacuauac gccggacaug acccacagcg agguggagaa agccuuuaag aaggcguuua      480

aggucuggag ugacgucacc ccguuaaacu ucacgcgcuu gcaugacggg aucgccgaua      540

uaaugauuag cuucgggauc aaagaacacg gggauuuuua uccguucgac ggcccgagcg      600

gguuauuagc ccacgccuuc ccgccgggcc cgaacuacgg gggggacgcg cacuucgacg      660

acgacgagac guggaccucg ucgaguaagg gguauaaucu cuucuugguc gccgcccacg      720

aauuugggca uagucucggg uuggaucaua guaaagaucc gggggccuug auguucccga      780

uauauacgua uacggggaag ucgcauuuca uguugccgga cgaugacguc cagggcauac      840

aaaguuugua cgggccgggg gacgaggauc cgaauccgaa gcacccgaag accccggaua      900

agugcgaucc gagucucagu uuggacgcga ucacgucguu gaggggggag accaugauau      960

ucaaggaucg cuuuuuuugg agguuacacc cgcaacaagu cgacgccgaa uuauuccuca     1020

ccaagagcuu cuggccggag uugccgaaua ggaucgacgc cgccuacgaa cauccgagcc     1080

acgauuugau auuuauauuu cgcgggcgca aguucugggc cuugaacggg uacgauaucu     1140

uagaggggua cccgaagaag aucagcgagu uaggguugcc gaaggagguc aaaaaaaucu     1200

cggccgccgu ccauuucgaa gacaccggga aaaccuuguu auuuagcggg aaucaagugu     1260

ggcgcuacga cgacaccaau cacaucaugg acaaggauua cccccgcuug aucgaggagg     1320

auuuuccggg gaucggggac aaggucgacg ccguguacga aaagaacggg uacauauacu     1380

ucuuuaaugg gccgauccaa uucgaguauu cgauaugguc gaauaggauc gucaggguga     1440

ugccggccaa caguauccuc uggugcugag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  5728
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt10)

<400>  5728
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

ccccgaacac caccgaagau uacgacacca caaccgaguu cgacuacggc gacgccaccc      120

ccugccaaaa agucaacgaa cgcgccuucg gcgcccaacu ccucccaccc cuuuacuccc      180

ucgucuucgu caucggccuc gucggcaaua uccucguagu ccucguccuc guccaauaca      240

aacgacucaa aaacaugacc uccaucuacu uacucaacuu agccaucucc gaccuccucu      300

uccucuucac ccuccccuuc uggauagacu acaaacucaa agacgacugg gucuucggcg      360

acgccaugug caaaauccuc ucgggcuucu acuacacagg acucuacucc gaaaucuucu      420

ucaucauccu cuuaacuauc gaccgcuacc uagccaucgu ccacgccguc uucgcacuac      480

gcgcccgcac cguaaccuuc ggcgucauca ccucaaucau caucugggcc cucgccaucc      540

ucgccuccau gcccggccuc uacuucucaa aaacccaaug ggaguucaca caccacacau      600

gcucacucca cuucccccac gaauccuuac gcgaauggaa acucuuccaa gcccucaaac      660

ucaaccuauu cggccuaguc cucccacuac ucgucaugau caucugcuac acaggcauca      720

ucaaaauacu ccuccgccgc cccaacgaaa agaaauccaa agcaguccgc cucaucuuug      780

ucauaaugau aaucuucuuc cuauucugga cccccuacaa ccucaccauc cucaucucag      840

uauuccaaga cuuccucuuc acccaugaau gcgaacaauc acgccacuua gaccucgccg      900

uccaagucac cgaggucauu gccuacaccc acugcugcgu caacccagua aucuacgccu      960

ucgucggcga acgcuuccgc aaauaccucc gucaacuauu ccaccgacgc gucgccguac     1020

accucgucaa auggcucccc uuccuaucug ucgaccgauu agaacgcguc uccuccacaa     1080

gcccaagcac cggcgaacac gaacucuccg ccggcuucug aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  5729
<211>  1018
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt10)

<400>  5729
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcgaa       60

cauuagcaug cuuguuguua uuagguugcg gguacuuagc gcacguguua gcagaggagg      120

cagagauccc gcgugagguu aucgagcgcu uggcacgauc gcagauccac aguauccgag      180

acuuacagcg guuguuggag aucgacucag ucggcucgga ggacucguua gacacgaguu      240

uacgagcgca cggggugcac gccacgaagc acguaccgga gaagcgcccg uugccgauac      300

gucgcaagcg aucgaucgag gaggcggugc ccgcgguuug caagacgcga accgucaucu      360

acgagauccc acgaucgcag guagacccua ccucggcuaa cuucuuaaua uggccuccau      420

gcguagaggu caagcguugc acggggugcu gcaacacauc gucgguuaag ugccagccgu      480

cgcgagugca ccaccguucg guaaaggugg ccaagguuga guacguacga aagaagccca      540

agcuaaagga gguucagguu cgauuggagg agcacuuaga gugcgcuugc gccacgacga      600

guuugaaccc cgacuaccgu gaggaggaca cggggcgacc gcgcgagucg ggcaagaagc      660

gaaagcgaaa gcgguugaag ccgacgugag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc      960

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1018


<210>  5730
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt10)

<400>  5730
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacc       60

guugcugggc ccuuuucuug ucguuaugcu gcuacuugcg cuuggugucg gccgagggug      120

auccgauacc ggaggagcug uacgagaugc uaucugacca caguauaagg ucauucgacg      180

acuugcagcg auuauuacac ggggacccgg gugaagagga cggggcggag uuagacuuaa      240

acaugacgcg cucgcacucg gguggggagu uggagucguu agcgcggggg cggcgaucgu      300

uagggucguu gacgaucgcg gagccugcga ugaucgcgga gugcaagacg cguacggagg      360

ucuucgagau aucgcgacgu uuaaucgacc gaaccaacgc aaacuucuua guauggcccc      420

cuugcgucga gguacagagg ugcaguggau gcugcaacaa ccgaaacguc cagugcaggc      480

cgacgcaggu ucaguugcgu ccgguacaag uccguaagau cgagaucguc cguaagaagc      540

cgauauucaa gaaggcuacg guaaccuuag aggaccaucu cgccugcaag ugcgagacug      600

ucgccgcggc gaggccggua acucggucgc ccggugggag ucaggagcag cgugcgaaga      660

cgccgcagac gcgaguuacc auaaggaccg uacgugugcg ucguccgccg aaaggaaagc      720

accgaaaguu caagcacacg cacgacaaga cugccuuaaa ggagacguua ggugccugag      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  5731
<211>  1420
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt10)

<400>  5731
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucgu       60

uauucggcuu guuauuauug acgagugcgu uagcagggca gcggcaaggu acacaggcag      120

agucgaaccu cucgucgaag uuccaguucu cgucgaacaa ggagcagaac ggugugcagg      180

acccacagca cgagcguauc aucacgguuu cgacaaacgg gucgauacac ucgccgcguu      240

ucccacacac guacccgcga aacacugugu uagucuggcg ucucguugcc gucgaggaga      300

acguuuggau ccaguuaacu uucgacgaga gguucgguuu agaggacccg gaggacgaca      360

ucugcaagua cgacuucguu gagguagagg agccuucaga cgguacgauc uugggacgau      420

ggugcggguc ggggaccguu cccgggaagc agauaucgaa ggggaaccag auacgaaucc      480

gauucgucuc ggacgaguac uucccgucgg agccggguuu cugcauacac uacaacauag      540

uaaugccgca guucacggag gccguuucgc cgucugucuu accgcccucg gcguuaccgu      600

uagacuuacu caacaacgcg aucacggcgu ucucuacguu agaggacuua auacguuacu      660

uagagccgga gcgauggcaa uuagacuugg aggacuugua ccgccccacc uggcaguuac      720

ucgguaaggc auucguauuc gggcgaaaga gucgaguagu agacuuaaau uuauuaaccg      780

aggagguucg acuauacucu ugcacucccc gcaacuucuc gguuucgauc cgagaggagc      840

uuaagcgcac ggacacgaua uucuggccgg ggugcuuauu ggucaagagg ugcgggggua      900

acugcgcgug cugccuucac aacugcaacg agugccagug cgugccgucg aaggucacaa      960

agaaguacca cgaggucuua caacuucgcc ccaagacggg cgugcgaggu uuacacaaga     1020

gucuaacuga cguagcgcuc gagcaccacg aggagugcga cugcgucugc agggggucga     1080

ccggggggug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag     1140

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc     1200

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu     1260

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1380

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1420


<210>  5732
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt10)

<400>  5732
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

gacuaaucuu cguauacacc uugauaugcg ccaacuucug cuccugccga gacacgucgg      120

ccacucccca gucggcuagu auaaaggccc uucguaacgc gaacuugcgu cgggacgacc      180

uuuacaggag ggacgagacu auccagguca agggcaacgg auacguccaa ucgccccggu      240

uccccaacag uuacccgcgg aacuuacuuu ugaccuggcg uuuacacucg caggagaaca      300

cgaggaucca auuaguuuuc gacaaccagu ucggccucga ggaggccgag aacgacauau      360

gccgauacga cuucguagag guagaggaca ucagugagac cucgacgaua aucagggggc      420

gguggugcgg ccacaaggag guacccccuc gaaucaagag ucgaaccaac cagaucaaga      480

uaaccuucaa gucggacgac uacuucguag caaagccggg guucaagaua uacuacucgc      540

ucuuagagga cuuccagccg gcggccgcgu cggagacaaa cugggagucg guaacgucgu      600

cgauaucggg ugugucguac aacucacccu cggucaccga cccgaccuug auagccgacg      660

cguuagacaa gaagaucgcc gaguucgaca cgguagagga cuuguugaag uacuucaacc      720

cggagucgug gcaggaggac uuagagaaca uguacuuaga cacgccgagg uacagggggc      780

ggucguacca cgaccgcaag ucgaaggugg acuuagaccg acuuaacgac gacgcgaagc      840

gauacucgug cacaccucga aacuacagug uaaacaucag ggaggaguua aaguuagcca      900

acgucguauu cuucccgcgg ugcuuauuag uucagcguug cgggggcaac ugcgguugcg      960

ggacggugaa cuggcgaucu ugcacgugca acucggguaa gaccguaaag aaguaccacg     1020

agguccuuca guucgagccc gggcacauaa agcgucgcgg ccgugcgaag accauggcgc     1080

ucguggacau ucaacucgac caccacgagc guugcgacug caucugcucg ucgcgaccuc     1140

cgcguugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  5733
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt10)

<400>  5733
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguaa       60

cgcacucgaa guucccggcg gcggguauga guaggccguu agacacaucg cuucguuuaa      120

agacauucuc gucgaagagu gaauaccagc ucguugucaa cgcgguccgg aaguugcaag      180

aaucagguuu cuauuggucg gcgguaacgg ggggggaggc aaauuuauua uugucggcgg      240

agccagcggg gacauucuua auccgugacu cgucugacca gcggcacuuu uuuacauuau      300

cagugaagac acaaucgggu acgaagaacc uucgaauaca gugcgagggc ggaaguuucu      360

cguugcagag ugacccgcga ucuacacagc cggucccucg auucgacugc guauuaaagu      420

ugguucacca uuacaugccc ccaccggggg cuccgaguuu cccgucaccg ccgacggagc      480

cgaguucgga gguaccggag cagccaucgg cgcagccuuu accggguucg ccgccucgac      540

gcgcguacua cauauacucg gggggugaaa agauuccacu cguauuaucg aggccuuuau      600

cgucgaacgu agcgacacuc caacacuugu gccgcaagac cguuaacgga cauuuagacu      660

cguacgagaa ggucacgcaa cucccaggcc cgaucaggga guucuuggac caguacgacg      720

cuccauuaug aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  5734
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt10)

<400>  5734
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugc       60

cgagcgccgg gcaauuggcg uuauuugccu uagggaucgu ccucgccgcc ugucaagcgc      120

ucgaaaauuc gaccaguccc uuaucggccg aucccccggu cgccgccgcc gucgucaguc      180

acuucaacga uuguccggac agucauaccc aauuuuguuu ucacgggacg ugucgcuucc      240

ucguccaaga agauaaaccg gccugcgugu gucacagcgg cuaugucggg gccaggugcg      300

aacacgccga uuuguuagcg gucgucgccg cgucgcaaaa aaaacaagcg auaacggcgc      360

ucgucgucgu gaguauaguc gcguuagccg uguugauaau aaccugcguc uuaauccauu      420

guugucaagu gaggaagcau ugcgaauggu guagagcguu gauauguaga caugaaaaac      480

cgucggcguu guuaaaaggg cgcacggccu guugucauag cgagaccguc gugugaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5735
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt10)

<400>  5735
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccc       60

cgucugguuu acgauuauua cccuuauugu uacccuuauu gugguuauua guauugaccc      120

ccgggcgacc ggccgccggc uuaaguacgu gcaagaccau cgacauggag uuaguaaagc      180

ggaagcgaau agaggcgaua cgagggcaga ucuuaucgaa guuacgauua gccaguccgc      240

ccucgcaggg cgagguaccg cccgggcccu ugcccgaggc cguauuagcg uuauacaaca      300

guacccgaga ccgaguagcg ggugagucug cggagcccga gcccgagccc gaggccgacu      360

acuacgccaa ggagguaaca cgaguauuga ugguagagac ccacaacgag aucuacgaca      420

aguucaagca gaguacgcac ucuaucuaca uguucuucaa cacgagugag uuacgagagg      480

cgguucccga gcccguauua uuaagucgag cggaguuacg auuauugcga uuaaaguuaa      540

agguagagca gcacguagag uuauaccaga aguacaguaa caacucuugg cgauacuuau      600

caaaccguuu auuagcgccg ucugacaguc ccgagugguu aucuuucgac guaacggggg      660

uaguacgaca gugguuaagu cgugggggcg agauagaggg guuccgauug ucagcgcacu      720

gcaguugcga cucucgggac aacacguugc agguagacau caacggcuuc acgacggggc      780

gacgaggcga cuuagccacc auacacggca ugaaccgacc cuucuuauua uuaauggcca      840

cgcccuuaga gcgugcgcag cacuuacagu cuagucgaca ccgacgagcc uuagacacca      900

acuacugcuu caguucgacc gagaagaacu gcugcguacg acaguuauac aucgacuucc      960

gaaaggacuu aggguggaag uggauacacg agccgaaggg cuaccacgcg aacuucugcu     1020

uagggcccug ccccuacauc uggucguuag acacgcagua caguaaggua uuagccuuau     1080

acaaccagca caaccccggc gccucggcgg ccccgugcug cguaccgcag gcguuggagc     1140

ccuuacccau aguauacuac guaggccgua agccgaaggu agagcaguua aguaacauga     1200

uaguacgauc gugcaagugc aguugaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  5736
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt10)

<400>  5736
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugcguauu aucugcguuc uugauauuac acuuaguuac cguggcauug aguuuaucca      120

cuugcaguac guuagacaug gaccaguuca ugcgaaagcg aauagaggcu auaagggguc      180

agauuuuguc gaagcucaag uuaacgucuc cuccggagga cuaccccgag ccggaagagg      240

uaccgccgga gguaaucagu auauacaacu cgacgcgaga ccuuuuacag gaaaaggcau      300

cgcgacgcgc agcggcgugc gagagggagc guucggacga ggaguacuac gcgaaggaag      360

uauacaagau cgacaugccu ccguucuucc cgucggagaa cgcgauccca ccuacguucu      420

aucgaccgua cuuccgcauc gucagguucg acguaagugc gauggagaag aacgccucua      480

acuuaguaaa ggcggaguuu cgaguauuca gguuacagaa cccgaaggcg cgaguucccg      540

agcagaggau cgaguuauac cagaucuuaa agaguaagga ccuuacuucg ccuacgcaac      600

gauacauaga caguaaggua guaaagacgc gagccgaggg agagugguua ucguucgacg      660

ucacggacgc gguccacgag ugguuacacc acaaggaccg caaccuuggc uucaagauca      720

gucuccacug cccgugcugc acauucgucc cuucgaacaa cuauauaaua ccgaacaagu      780

cggaggaguu agaggcucgu uucgcgggaa ucgacgggac gucgacguac acgucgggag      840

accagaagac gaucaagucg acgcgaaaga agaacucggg aaagacaccg cacuuguuau      900

uaauguuguu accgucguac agguuagagu cgcagcagac gaaccgccga aagaagcgag      960

cgcuagacgc agcguacugu uuccgaaacg uacaagacaa cugcuguuua aggcccuuau     1020

acaucgacuu caagcgcgac uuggguugga aguggaucca cgagccuaag gguuauaacg     1080

caaacuucug cgcaggcgcg ugccccuacc ucuggucguc ggacacccaa cacagucgag     1140

uguuaucucu uuacaacacg aucaaccccg aggcgagugc cucgccgugc ugcgucucgc     1200

aggacuugga gccauuaacg aucuuguacu acaucgguaa gacgccuaag aucgagcagu     1260

uaucgaacau gauagucaaa aguugcaagu gcucaugagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  5737
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt10)

<400>  5737
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

ugcacuugca gagggcguug guaguauuag cguuauugaa cuucgcgacg guaucguuaa      120

guuuaucgac augcacgacg uuggacuucg gccacaucaa gaagaagcgc guagaggcga      180

uacgggguca gauauuaagu aaguuacgcu ugacgucgcc gccggagccg acgguaauga      240

cacacguacc guaccaggua uuagcguuau acaacaguac gagggaguug uuagaggaga      300

ugcacgguga gcgcgaggag gguugcacgc aggagaacac ggagucggag uacuacgcga      360

aggagauaca caaguucgac augauacagg guuuagcgga gcacaacgag uuggcgguau      420

gccccaaggg gauaacgagu aaggucuuca gguucaacgu aucgagugua gagaagaacc      480

gcacgaacuu auucagggcg gaguuccgag uauuaagggu cccgaacccg ucgaguaagc      540

gaaacgagca gaggauagag uuauuccaga uauuacgccc cgacgagcac auagcgaagc      600

agcgguacau aggggguaag aacuuaccca cgcgcgguac ggcugagugg uugucguucg      660

acguaacaga cacgguaagg gagugguuau uacgcaggga gaguaacuug ggcuuagaga      720

uaucgauaca cugcccuugc cacacguucc agccgaacgg ggacauauua gagaacauac      780

acgagguaau ggagauaaag uucaagggug uagacaacga ggacgaccac gggcgagggg      840

acuuggggag guuaaagaag cagaaggacc accacaaccc ccacuuaaua uugaugauga      900

uaccgccgca ccgauuagac aaccccgguc agggggggca gcgaaagaag agggcguuag      960

acacgaacua cugcuuccga aacuuggagg agaacugcug cguaaggccg uuauacauag     1020

acuuccgcca ggacuuaggg uggaaguggg uacacgagcc gaaggguuac uacgcuaacu     1080

ucugcagugg uccgugcccc uacuugaggu cggcagacac aacgcacagu acgguauuag     1140

guuuauacaa cacguugaac ccggaggcgu cggcuagucc gugcugcgua ccgcaggacu     1200

uagagcccuu aacaauauug uacuacguag ggagaacgcc gaagguagag caguuaucga     1260

acaugguagu aaagucgugc aagugcaguu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  5738
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt10)

<400>  5738
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggccc       60

cgguggcggu cugggcggcu uuagcgguag ggcuugagcu uugggcggcc gcgcacgcgu      120

uaccggcgca ggucgcguuc acgcccuacg cucccgagcc ggguucaacg ugcagguugc      180

gcgaguacua cgaccaaacu gcgcagaugu gcugcucgaa gugcuccccg ggacagcacg      240

cgaagguauu cugcaccaaa acaucagaca cggugugcga cucgugcgag gacucgacuu      300

acacgcaauu auggaacugg gugcccgagu gccucucgug cggaucgcga ugcucgucag      360

accaaguaga gacccaggcc ugcacgcgcg agcaaaaccg gaucugcacg ugccgcccgg      420

gcugguacug cgccuugucg aagcaggagg guugccgacu cugcgcgccc cuccgaaagu      480

gccggccggg uuucggggua gcgcgaccug ggacggagac gucggacgua gucugcaagc      540

cgugcgcgcc cggaacauuc ucuaacacga caucgucuac cgacaucugc cgcccgcacc      600

agaucugcaa cgucguugca aucccgggga acgcgaguau ggacgcggua ugcacaucga      660

cgucgccgac gcgcucaaug gcgccgggcg ccgugcaccu uccgcagccc guaucgacgc      720

ggucgcagca cacccaaccg acgccggagc cgucgaccgc gccgucgacu ucguuccuuu      780

uacccauggg gcccucgccg cccgcggagg gcucgaccgg ugacuucgcg uugccgguag      840

gguuaaucgu gggcgucacg gcguuagggu uguuaaucau cggcgucgua aacugcguga      900

uaaugacgca gguaaagaag aagccgcugu gcuugcagcg agaggcgaag gugccgcacu      960

uaccggccga caaggcccgu ggcacgcagg gucccgagca gcagcacuua uuaauuaccg     1020

cgccgucguc gaguucgagu ucguuggagu cgagcgcauc ggcccuagac aggcgagccc     1080

ccacgcgaaa ccagccgcag gcgccgggug uggaggcguc uggggccggc gaggcccgug     1140

ccucgaccgg aucgucggac ucgucgccgg gcggacacgg uacacaggua aacguaacuu     1200

gcaucguuaa cguaugcucg ucgucggacc acucgaguca gugcucgagu caggcgucgu     1260

cgacgauggg ggacacugac ucgucgcccu cagagagucc uaaggacgag caggucccgu     1320

ucucgaagga ggagugcgcc uuccguaguc aacucgagac accggagacg cuccucggau     1380

caacggagga gaagccguua cccuuaggcg uuccggacgc ggggaugaag ccgucgugag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  5739
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt10)

<400>  5739
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

uaaugcgcuu auuuccaugu uucuugcagu uauuagcggg cuuggccuua cccgcaguac      120

caccgcaaca augggcucuc ucggcaggga acgguaguuc ggaaguugag gucgucccgu      180

uccaggaggu cuggggucga aguuacugca gggcccuuga gcgccucgug gacguaguaa      240

gugaguaucc gagugaggua gagcauaugu ucucgccuag uugcguuucu uuauugaggu      300

guacagguug cugcggugac gagaacuuac acugcguacc cguagagacc gccaacguaa      360

cuaugcaauu auugaagauu cgaucgggag accguccauc guacguagag uuaaccuuua      420

gucagcaugu ccguugcgag ugccguccgc uucgcgagaa aaugaagccc gagcgucgaa      480

ggccuaaagg gcgcgggaag cggcgcaggg agaaacagcg accuacggac ugucacuugu      540

gcggggacgc ggucccgcga cgcugaggac uagugcauca cauuuaaaag caucucagcc      600

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu      660

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu      720

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  5740
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt10)

<400>  5740
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

accgccagac cgacacggcc cccucgccgu ccuaccaccu cuuacccggc cggcgccgga      120

ccguggacgc cgcggccucg cgcgggcagg gccccgagcc cgcccccggg ggcggggucg      180

agggcguggg cgcccgcggg guggccuuaa aguuauucgu ccagcucuua ggcugcuccc      240

gguucggggg cgcgguggug cgggccgggg aggccgagcc cucgggcgcc gcgcgcuccg      300

ccucguccgg ccgggaggag ccccagcccg aggaggggga ggaggaggag gagaaggagg      360

aggagcgcgg cccgcagugg cgguuagggg cccgcaagcc cggcucgugg accggcgagg      420

ccgccgucug cgcggacucc gcccccgccg cccgggcccc gcaggcgcuc gcccgcgccu      480

cggggcgggg cgggcgcgug gcccggcgcg gcgccgagga guccgggccg ccccacucgc      540

ccucccggcg cggcucggcg ucccgggccg gccccgggcg cgccucggag accaugaacu      600

ucuuauuauc cugggugcac uggucgcucg ccuuauuacu cuacuuacac cacgccaagu      660

ggucccaggc ggccccgaug gccgagggcg ggggccagaa ccaccacgag gucgugaagu      720

ucauggacgu guaccagcgc ucguacugcc accccaucga gacguuaguc gacaucuucc      780

aggaguaccc cgacgagauc gaguacaucu ucaagcccuc gugcgugccg cucaugcggu      840

gcgggggcug cugcaacgac gagggcuuag agugcgugcc caccgaggag uccaacauca      900

ccaugcagau caugcgcauc aagccccacc aggggcagca caucggcgag augucguucu      960

uacagcacaa caagugcgag ugccggccca agaaggaccg cgcccggcag gagaagaagu     1020

ccguccgcgg gaagggcaag gggcagaagc ggaagcgcaa gaagucccgg uacaagucgu     1080

ggucggugua cgugggcgcg cgcugcugcc ucaugccgug guccuuaccc ggcccccacc     1140

ccugcgggcc gugcucggag cggcgcaagc acuuauucgu ccaggacccg cagacgugca     1200

agugcucgug caagaacacg gacucgcggu gcaaggcgcg ccagcucgag uuaaacgagc     1260

ggacgugccg cugcgacaag ccgcggcgcu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  5741
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt10)

<400>  5741
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

ucuuauuguc guggguccac uggaguuuag cguuauuguu auacuuacac cacgcgaagu      120

ggucgcaagc agcgccgaug gcggaggggg guggucaaaa ccaccacgag guaguaaagu      180

ucauggacgu guaccagagg ucguacugcc acccgauaga gacguuggua gacauauucc      240

aagaguaccc ggacgagauc gaguacaucu ucaagccguc gugcguaccg uuaaugcgcu      300

gcggugguug cugcaacgac gaggguuuag agugcguccc uacggaggag aguaacauca      360

cuaugcagau aaugaggauu aagccgcauc aagggcagca cauaggggag augucguucu      420

ugcagcauaa caagugcgag ugccgaccga agaaggaccg agcgcgacag gagaagaaga      480

guguaagggg uaaagggaag ggucaaaagc gcaagaggaa aaagagucga uacaagucgu      540

ggucgguaua cgucggggcc aggugcugcu uaaugccgug gucguuacca gggccgcacc      600

cgugcgggcc gugcucggag cgcaggaagc acuuauucgu acaggaccca cagacgugca      660

agugcaguug caagaacacg gacucgcguu gcaaggcacg acaguuagag uuaaacgagc      720

gaacgugccg gugcgacaag ccucgaaggu gaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  5742
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt10)

<400>  5742
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucgc       60

cguuauugag gagguuauua uuggcggccu uguuacaauu agcgccggcg caagcgccgg      120

ugagucaacc ggacgcgccg gggcaucaac gcaaggucgu cagcuggauc gacgucuaca      180

ccagggccac gugucaaccg agagaagucg ucgucccgcu caccgucgaa uugaugggga      240

cggucgcgaa gcaauuaguc ccgucgugug ucaccgucca aaggugcggg ggguguuguc      300

cggaugacgg guuagaaugc gucccgaccg gccaacauca ggugagaaug caaauauuga      360

ugauaagaua ucccucgucg caauuaggcg aaaugaguuu agaggagcau ucgcaaugcg      420

agugucgccc gaagaagaaa gauucggccg ucaaaccgga ucgcgccgcg accccgcauc      480

auaggccgca accgaggagc guccccgggu gggauagcgc gccgggggcc ccgaguccgg      540

ccgauauaac gcacccgacc ccggcgccgg ggccgagcgc gcaugccgcc ccgucgacga      600

cgucggcguu aacgccgggg ccggcggccg cggccgcgga ugcggccgcc aguagugucg      660

cgaaaggggg cgccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  5743
<211>  1642
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt10)

<400>  5743
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ucuuaggguu cuucagcguc gccugcuccu uacuggcggc ggcccuccug cccgggccgc      120

gcgaggcccc ggcggcggcg gcggcguucg agagcggccu ggaccucucc gacgccgagc      180

cggacgcggg ggaggcgacc gccuacgccu cgaaggacuu agaggagcag cugcgguccg      240

ucagcuccgu ggacgagcuc augaccgugc uguaccccga guacuggaag auguacaagu      300

gccaguugcg caagggcggg uggcagcaca accgggagca ggcgaaccuc aacagccgca      360

cggaggagac caucaaguuc gcggccgccc acuacaacac cgagauccuc aaguccaucg      420

acaacgagug gcggaagacc cagugcaugc cgcgcgaagu cugcaucgac gucggcaaag      480

aguucggcgu ggccacgaau acguuuuuca agccgcccug cgucagugug uaucggugcg      540

ggggcuguug uaacuccgaa ggguuacaau guaugaauac gucgaccucg uauuuaucga      600

aaacgcuguu cgagaucacc guccccuugu cccaggggcc gaagcccguc accauaucgu      660

ucgcgaacca uaccucgugu cgcuguauga gcaaguuaga cguguaucgc caggugcacu      720

cgaucauccg gcggaguuua cccgcgacgu ugccccaaug ccaagccgcc aauaaaacgu      780

guccgacgaa cuauaugugg aacaaccaua uaugucgcug uuuagcccaa gaggacuuca      840

uguucaguuc cgacgccggg gacgauagca ccgacggcuu ucacgauaua ugcggcccca      900

auaaagaauu agacgaggaa acgugccaau gcgucugucg ggcgggguug cgccccgcgu      960

cgugcggccc gcauaaggag cucgaucgga auagcuguca augcgugugc aagaauaagu     1020

uguuuccguc gcagugcggg gcgaaucgcg aguucgacga gaauacgugu caaugcgugu     1080

gcaagcggac guguccgcgc aaccagccgu ugaaccccgg caagugcgcg ugcgagugca     1140

ccgagucgcc gcaaaagugu cuccugaagg gcaagaaauu ucaucaucag accuguucgu     1200

gcuaucggcg ccccugcacc aaucggcaaa aagccugcga acccggguuc agcuacuccg     1260

aggaggucug ccgcugcgug cccagcuacu ggaagcgccc gcagaugucg ugaggacuag     1320

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1380

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1440

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1500

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1620

ucuuuucaga gccaccagaa uu                                              1642


<210>  5744
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt10)

<400>  5744
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguaca       60

gggaaugggu cguagucaac gucuucauga uguuauacgu acaauuagua caagguucgu      120

cgaacgagca cgguccgguc aagcguucgu cgcaaucgac guuagagcgu ucggagcagc      180

agauacgagc ggcgucgucg uuagaggagu ugcuacggau aacgcacucg gaggacugga      240

aguuauggcg augucgauua cgcuuaaagu cguucacauc gauggacucg aggucggcuu      300

cgcaccgcuc gacgcgguuc gccgcgacau ucuacgacau agagacguua aaggucaucg      360

acgaggagug gcagcgcacg cagugcucgc cgagggagac uugcgucgag gucgcgucag      420

aauuggguaa gucgacuaac acguuuuuca agccuccgug cguuaacguc uuccguugcg      480

gggguugcug caacgaggag ucguuaaucu gcaugaacac aaguacguca uacaucucga      540

agcaauuauu cgagaucucg gucccauuaa ccucgguccc ggaguuggug ccgguaaagg      600

uagcgaacca cacggggugc aagugcuuac cgacggcucc gcgacacccg uacaguauaa      660

uacgacgguc gauacagauu cccgaggagg accgaugcag ucacucgaag aagcuaugcc      720

caaucgacau gcucugggac aguaacaagu gcaagugcgu auuacaggag gagaaccccu      780

uggcggggac ggaggaccac ucgcacuugc aggagccggc guugugcgga ccgcacauga      840

uguucgacga ggaccggugc gagugcguau gcaagacucc gugcccgaag gacuugauuc      900

agcacccuaa gaacugcucg ugcuucgaau gcaaggaguc guuagagacg ugcugccaga      960

agcacaaguu guuccacccg gauacaugca guugcgagga ccgaugcccg uuccacacac     1020

gacccugcgc gucggguaag acggcuugcg cgaagcacug ccgauucccu aaggagaagc     1080

gagcggcaca ggguccgcac ucucguaaga acccgugagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  5745
<211>  1030
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt10)

<400>  5745
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggua       60

aaggugaccc gaaaaagcca cgcgguaaga ugaguucgua ugcguucuuc guccaaacgu      120

gccgagagga acacaagaaa aagcacccgg acgcgucggu aaacuucucg gaguucucaa      180

aaaagugcuc cgaacgcugg aagacgaugu cggcgaaaga gaaagguaaa uuugaagaua      240

uggcgaaagc ggacaaggcg cgcuacgaga gggagaugaa gacauauaua ccgccgaagg      300

gugagaccaa gaaaaaguuc aaggacccga acgcgccgaa gcggccgccg ucugcguuuu      360

uccuuuucug uucggaguac cgcccgaaga uaaagggaga gcacccgggc cuuucgauag      420

gcgacguagc gaaaaaguug ggugaaaugu ggaauaacac ggcggcggac gauaaacagc      480

cauaugaaaa gaaagcagcg aagcucaagg aaaaguacga gaaagauauc gcggcauauc      540

gagcaaaagg uaaaccggac gcggcgaaga aagguguagu aaaagcagaa aagucgaaga      600

aaaagaaaga ggaagaggaa gaugaagagg acgaggaaga ugaagaggaa gaggaagaug      660

aagaggacga ggacgaggaa gaggacgaug acgaugaaug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1020

caccagaauu                                                            1030


<210>  5746
<211>  977
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt10)

<400>  5746
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg aaaccggcuu cgaacacuca ggccucuggg      120

ucuccguacu agccggccuc cuccucggcg ccugccaagc ccaccccauc cccgacuccu      180

caccccuccu acaauucggc ggccaagucc gccaacgcua ccuauacacc gacgacgccc      240

aacaaaccga agcccaccuc gaaauccgcg aagacggcac cgucggcggc gccgccgacc      300

aaucccccga aucccuacua caacucaaag cccucaaacc uggagucauc caaauacucg      360

gcgucaaaac cucccgcuuc cucugccaac gccccgacgg agcccucuac ggcucccucc      420

acuucgaccc agaagccugc ucuuuccgag aacuccucuu agaagacggc uacaacgucu      480

accaaucuga agcccacggc cucccccuuc accuccccgg aaacaaauca ccccaccgcg      540

accccgcacc ccgcggccca gccagauucc ucccccuccc cggccuccca ccagcccucc      600

ccgaaccacc cggcauccuc gcaccccaac cacccgacgu cggcuccucc gacccccucu      660

caauggucgg ccccucccaa ggccgcuccc ccucauacgc cucaugagga cuagugcauc      720

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      780

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      840

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      900

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aagaauu                                                     977


<210>  5747
<211>  1757
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt10)

<400>  5747
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauucguucc cgccguuauu auuauuauua uuuugggggg      120

ucgucagcca uucguuuccg gccaccuugg agacccagga acaggacguc gaucucgugc      180

aaaaguauuu agagaaguau uauaauuuaa aaaacgacgg ccgccagguc gagaaaagac      240

gcaacucggg gccggucguc gagaagcuca aacagaugca agaguuuuuc ggcuuaaagg      300

ucaccggcaa gccggacgcc gagacguuaa aagucaugaa acaaccgcgc ugcggggucc      360

cggacgucgc ccaauucgug uugaccgaag gcaauccgag gugggaacag acccacuuaa      420

cguaucgcau cgagaacuau accccggacc ucccgcgcgc cgacgucgau cacgcgaucg      480

aaaaggcguu ucaguugugg ucgaacguga ccccguuaac cuuuacgaaa gugagcgaag      540

ggcaggccga uauaaugauc agcuucgugc gcggggacca cagagauaau agcccguucg      600

acgggccggg ggggaacuug gcccacgccu uccagccggg gccggggauc gggggcgacg      660

cccacuucga cgaggacgag cgcuggacga auaacuuucg cgaauauaau cuccacaggg      720

ucgccgccca cgaguugggg cacagcuugg gguugaguca cagcaccgac auaggcgccc      780

ucauguaucc gucguauacg uuuucggggg acguccaauu ggcccaagac gauaucgacg      840

ggauacaggc gaucuacggg aggagucaga acccggugca accgauaggg ccgcagacgc      900

cgaaggccug cgauucgaaa uugacguucg acgccaucac caccaucaga ggggagguca      960

uguuuuucaa ggaucgcuuu uauaugagga ccaacccguu uuaucccgag gucgaauuga     1020

acuuuaucag cgucuuuugg ccgcaguuac cgaacggcuu ggaggccgcc uaugaguucg     1080

cggaucgcga cgaggugaga uucuuuaagg gcaacaaaua uugggccguc caagggcaaa     1140

acgucuugca uggguauccg aaagauauau auucgaguuu cggguuuccg cgcaccguca     1200

aacacauaga cgccgccuug agcgaagaga auaccgggaa gacguauuuu uucgucgcca     1260

auaaguauug gcgcuacgac gaguacaaga ggagcaugga cccgggguac ccgaagauga     1320

ucgcccacga uuucccgggg aucgggcaua aggucgacgc cgucuuuaug aaggacgggu     1380

ucuuuuacuu uuuccacggg acccgccagu auaaguucga cccgaagacc aaacgcaucc     1440

ucaccuugca aaaggccaac ucgugguuua auugucgcaa gaacugagga cuagugcauc     1500

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1560

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1620

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1680

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aagaauu                                                    1757


<210>  5748
<211>  3413
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt10)

<400>  5748
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcgcaagu gccugagcaa gcggcucaug cuggccauca      120

ccauggccac caucuucacg gugaacucca cccugcccau cuacgcggcc gucgacaaga      180

acaacgccac cgccgccgug cagaacgaga gcaagcgcua caccgugucc uaccucaaga      240

cgcugaacua cuacgaccug gucgaccucc uggugaagac cgagaucgag aaccugccgg      300

accucuucca guacagcucc gacgcgaagg aguucuacgg caacaagacc cggaugagcu      360

ucaucaugga cgagaucggg cgccgggcgc cccaguacac cgagaucgac cacaagggca      420

uccccacgcu gguggagguc gugcgcgccg gguucuaccu gggcuuccac aacaaggagc      480

ucaacgagau caacaagcgg uccuucaagg agcgcgugau ccccagcauc cuggccaucc      540

agaagaaccc gaacuucaag cuggggaccg agguccagga caagaucgug uccgccaccg      600

gccuccuggc cggcaacgag accgccccgc ccgagguggu caacaacuuc acgcccaucc      660

ugcaggacug caucaagaac aucgaccggu acgcccucga cgaccucaag agcaaggccc      720

uguucaacgu gcucgcggcc ccgaccuacg acaucaccga guaccugcgc gccaccaagg      780

agaagcccga gaacacgccc ugguacggga agaucgacgg cuucaucaac gagcugaaga      840

agcucgcccu guacgggaag aucaacgaca acaacuccug gaucaucgac aacggcaucu      900

accacaucgc gccccugggg aagcuccaca gcaacaacaa gaucggcauc gagacccuga      960

ccgaggugau gaaggucuac ccguaccugu ccaugcagca ccuccagagc gccgaccaga     1020

ucaagcggca cuacgacucc aaggacgccg agggcaacaa gaucccccug gacaaguuca     1080

agaaggaggg gaaggagaag uacugcccca agaccuacac guucgacgac ggcaagguga     1140

ucaucaaggc cggggcccgc guggaggagg agaaggucaa gcggcuguac ugggccagca     1200

aggaggugaa cucccaguuc uuccgcgugu acggcaucga caagccccuc gaggagggca     1260

acccggacga cauccugacc auggucaucu acaacagccc cgaggaguac aagcugaacu     1320

ccgugcucua cggguacgac accaacaacg gcgggaugua caucgagccc gagggcaccu     1380

ucuucacgua cgagcgggag gcgcaggaga gcaccuacac ccuggaggag cuguuccgcc     1440

acgaguacac ccacuaccuc caggggcggu acgccgugcc cggccagugg ggccgcacga     1500

agcuguacga caacgaccgg cugaccuggu acgaggaggg cggggccgag cuguucgccg     1560

ggagcacccg caccuccggc auccugccgc gcaagagcau cgucuccaac auccacaaca     1620

cgacccggaa caaccgcuac aagcugagcg acaccgugca cuccaaguac ggggccagcu     1680

ucgaguucua caacuacgcg ugcauguuca uggacuacau guacaacaag gacaugggca     1740

uccucaacaa gcugaacgac cuggccaaga acaacgacgu cgacggcuac gacaacuaca     1800

uccgggaccu cuccagcaac uacgcccuga acgacaagua ccaggaccac augcaggagc     1860

gcaucgacaa cuacgagaac cugaccgugc ccuucguggc cgacgacuac cugguccggc     1920

acgcguacaa gaaccccaac gagaucuacu ccgagaucag cgagguggcc aagcucaagg     1980

acgccaaguc cgaggugaag aagucccagu acuucagcac guucacccug cgcgggagcu     2040

acaccggcgg ggccuccaag ggcaagcugg aggaccagaa ggccaugaac aaguucaucg     2100

acgacagccu caagaagcug gacaccuacu ccuggagcgg guacaagacc cugacggcgu     2160

acuucaccaa cuacaagguc gacuccagca accgggugac cuacgacgug gucuuccacg     2220

gcuaccuccc caacgagggc gacagcaaga acucccugcc guacgggaag aucaacggca     2280

ccuacaaggg gacggagaag gagaagauca aguucagcuc cgagggcagc uucgaccccg     2340

acggcaagau cguguccuac gagugggacu ucggggacgg caacaagagc aacgaggaga     2400

accccgagca cuccuacgac aaggugggga ccuacaccgu caagcugaag gugaccgacg     2460

acaagggcga gagcuccgug agcacgacca ccgccgagau caaggaccuc uccgagaaca     2520

agcugcccgu caucuacaug cacgugccca agagcggggc ccugaaccag aagguggucu     2580

ucuacggcaa gggcaccuac gaccccgacg gguccaucgc cggcuaccag ugggacuucg     2640

gggacggcag cgacuucucc agcgagcaga accccuccca cguguacacg aagaaggggg     2700

aguacaccgu gacccuccgc gucauggaca gcagcggcca gauguccgag aagaccauga     2760

agaucaagau cacggacccg guguacccca ucggcaccga gaaggagccc aacaacagca     2820

aggagaccgc cuccgggccc aucgugccgg gcauccccgu cagcgggacc aucgagaaca     2880

cguccgacca ggacuacuuc uacuucgacg ugaucacccc cggcgaggug aagaucgaca     2940

ucaacaagcu gggguacggc ggcgcgaccu gggucgugua cgacgagaac aacaacgccg     3000

ugagcuacgc caccgacgac gggcagaacc uguccggcaa guucaaggcc gacaagcccg     3060

ggcgguacua cauccaccuc uacauguuca acggcagcua caugccguac cgcaucaaca     3120

ucgagggguc cgucggccgg ugaggacuag ugcaucacau uuaaaagcau cucagccuac     3180

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     3240

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     3300

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     3360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            3413


<210>  5749
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt10)

<400>  5749
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggucacga aguuguuacc ggcguuauua uuacaacacg      120

uguuguuaca cuuguuguua uugccgauag cgauaccgua ugccgaaggg cagcgcaagc      180

gccgcaauac cauccacgag uuuaagaaga gugccaaaac cacguugaua aagaucgacc      240

cggccuuaaa aaucaagacg aaaaagguca acaccgccga ucagugcgcc aaccgcugca      300

cccgcaacaa gggguugccg uuuaccugua aagccuucgu cuucgacaag gcccgcaagc      360

aauguuugug guuuccguuu aacucgauga gcucgggggu caagaaggag uucgggcacg      420

aguucgauuu guaugagaau aaggauuaua uccgcaauug uauaaucggg aaagggaggu      480

cguauaaagg gaccgucagc auaaccaaau cggggauaaa augccaaccg uggucgagua      540

ugaucccgca ugagcauucg uuccucccga gcucguacag agggaaggau uugcaagaga      600

auuauugcag gaacccgagg ggcgaggagg gcgggccgug gugcuuuacc ucgaacccgg      660

aagucaggua ugaggugugc gauaucccgc aaugcagcga ggucgagugu augacgugua      720

acggcgaauc guacaggggg uugauggacc acaccgagag cgggaaaauc ugccaaaggu      780

gggaccacca aaccccgcau agacauaaau uucucccgga gcgcuauccg gauaaagggu      840

ucgacgacaa cuacuguagg aacccggacg ggcaaccccg cccguggugu uauaccuugg      900

auccgcauac gaggugggaa uauugcgcca ucaaaaccug ugccgauaac accaugaacg      960

auaccgacgu cccgcucgag accaccgagu guauacaggg gcagggggag ggguaucgcg     1020

ggaccgugaa cacgaucugg aacgggaucc cgugccaaag gugggacagc caauauccgc     1080

augaacacga uaugaccccg gagaacuuua aauguaaaga uuugagggag aacuauugua     1140

ggaacccgga cggcagcgag agcccguggu gcuucacgac cgacccgaau auaagggucg     1200

gguauuguag ucagaucccg aauugcgaca ugagccacgg gcaagacugc uauaggggca     1260

acgggaaaaa cuacaugggg aaucucaguc agacccgcag cggguugacc ugcagcaugu     1320

gggauaaaaa uauggaggau cuccacaggc acauauuuug ggagccggac gccucgaaau     1380

uaaacgaaaa cuauuguagg aacccggacg acgacgccca cgggccgugg uguuauaccg     1440

ggaacccguu gaucccgugg gacuauuguc cgaucaguag gugcgagggg gacacgaccc     1500

cgaccaucgu gaaccucgau cacccgguca ucagcugcgc gaagaccaag cagcucaggg     1560

ucgucaacgg caucccgacc aggaccaaua ucggguggau ggucucgcuc cgcuaucgca     1620

acaagcacau augugggggg agccucauca aagaaucgug ggucuugacc gccaggcaau     1680

gcuuuccgag cagggaucuc aaggacuacg aggccugguu ggggauccac gacgugcaug     1740

ggcgcgggga cgaaaagugu aagcaagucu ugaacgucag ucaauuaguc uacgggccgg     1800

aggggagcga cuuaguccuc augaaauugg cgcgcccggc cguguuagac gacuucgucu     1860

cgaccaucga ccucccgaau uacgggugua ccaucccgga gaaaacgucg uguucggucu     1920

augggugggg guauaccggg cucauaaauu acgacggguu gcucaggguc gcccacuugu     1980

auaucauggg gaacgaaaag uguucgcaac accacagggg caaagucacc uuaaacgaaa     2040

gcgagaucug cgccggcgcc gagaaaaucg ggagcgggcc gugcgaaggc gacuaugggg     2100

ggccguuggu cugcgaacag cacaaaaugc gcauggucuu gggggugauc gucccgggga     2160

gggggugcgc gaucccgaac aggccgggga ucuucgugag ggucgccuac uacgccaagu     2220

ggauccauaa gaucauccuc accuauaaag ucccgcaaag cugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5750
<211>  923
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt10)

<400>  5750
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gguacgugga uacucuucgc gugcuuguua ggugcggcgu      120

ucgcgaugcc guuaccgccg cacccaggcc acccgggaua caucaacuuc ucguacgagg      180

ucuuaacgcc gcucaagugg uaccagagua uccgaccucc uuaccccucg uacggauacg      240

agccgauggg ggguugguua caccaccaga uaauaccagu auugagucag caacacccgc      300

caacgcacac uuuacagccg caccaccaca uccccguagu ccccgcgcag caaccgguca      360

ucccgcaaca gccgaugaug ccgguacccg ggcagcacuc gaugacaccu auccagcacc      420

accaaccgaa cuugccgccg ccggcgcagc aacccuacca gccacagccg guccagccuc      480

aaccccacca gccuaugcag ccucagccgc cgguacaccc gaugcagccg uuaccaccgc      540

agcccccguu accgcccaug uucccgaugc aaccccuccc gccgauguua ccggacuuaa      600

cguuagaggc guggccuucg acggacaaga cgaagcgcga ggagguugac ugaggacuag      660

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      720

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      780

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      840

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaga auu                                              923


<210>  5751
<211>  482
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt10)

<400>  5751
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccguugccgc cgcauccggg ucacccgggg uauauaaacu      120

ucucguauga ggucuugacg ccgcucaagu gguaccaauc gauucgcccg ccuuacccga      180

guuaugggua cgagccgaug gggggguggu gaggacuagu gcaucacauu uaaaagcauc      240

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      300

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      360

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa      480

uu                                                                     482


<210>  5752
<211>  926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt10)

<400>  5752
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gguacaugga uauuauucgc gugcuugguc ggugcugcau      120

ucgcaaugcc auuaccuccc cacccaggcc acccggggua cauuaauuuc ucguacgagg      180

uauuaacgcc gcuuaaaugg uaccagagua ugaucaggcc gccguacucg ucguacggau      240

acgaacccau gggggguugg uuacaucacc agauaauacc gguagucucg cagcagcacc      300

cguuaacgca cacguugcaa ucgcaccacc acauaccggu aguaccggcg cagcaaccuc      360

gcguuaggca gcaggcguua augccgguac cggggcagca gucgaugaca ccgacccagc      420

accaccagcc gaacuuacca uuacccgcuc aacagccauu ccagccgcaa cccguccagc      480

cgcaacccca ucagccgaug caaccgcaac cgccgguaca gccgaugcag ccguuguuac      540

cgcagccgcc guugccaccc auguucccgu uacgcccuuu accuccgauc uuaccggacu      600

uacacuuaga ggcauggccg gcgacggaca agacgaagca ggaggaggua gacugaggac      660

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      720

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      780

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      840

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa agaauu                                           926


<210>  5753
<211>  485
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt10)

<400>  5753
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccguugccgc cgcacccggg ccauccgggg uacauaaauu      120

uuucguacga agucuugacg ccgcucaaau gguaucaauc gaugauccgc ccgccguaua      180

gcaguuacgg guaugaaccg augggggggu ggugaggacu agugcaucac auuuaaaagc      240

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      300

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      360

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

gaauu                                                                  485


<210>  5754
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt10)

<400>  5754
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggagucg cgcgauugcc auugcucuua gguuuguuau      120

uauuaccacg cccggggagg ccccucgacu uagcggacua cacguacgac uuggcagagg      180

aggacgacuc ugaaccuuua aacuacaagg acccgugcaa ggcugccgcg uucuuagggg      240

acauagcguu ggacgaggag gacuuacgcg cuuuccaagu ccagcaggcg guugacuuaa      300

ggcgccacac ggcgcggaaa aguucgauca aggcggcggu acccgggaac acaaguacgc      360

cgucgugcca aaguacaaac ggacaaccac agcgcggggc gugcggacgg uggcgaggga      420

ggucgaggag uaggcgagca gccaccucgc gucccgagcg gguauggccg gacgguguaa      480

uuccauucgu aauagguggc aacuucacgg gaagucagcg ggcgguauuc cgccaggcga      540

ugcgacacug ggagaaacac acaugcguua cguucuugga gcgaaccgac gaggacucgu      600

acauaguauu uacguaccgu ccaugcggcu gcugcaguua cguagggcga agggguggcg      660

guccgcaagc gaucucgaua gguaagaacu gcgacaaguu cgguaucgua guucacgagu      720

uaggucacgu uguagguuuc uggcacgagc acacgcgacc ugaccgcgac aggcacguca      780

guauaguccg cgagaacaua cagccgggac aggaguacaa cuucuuaaaa auggagccgc      840

aagagguuga gucguugggu gagacguacg acuucgacuc gauaaugcac uacgcgcgaa      900

acacguucuc gcgcgggauu uucuuagaca caauaguucc gaaauacgag guaaacggcg      960

ucaagccgcc gauaggccag cggacucgcu ugucgaaggg ugacauagcg caggcgcgga     1020

aguuguauaa gugcccggcg ugcggugaga cauuacagga cucgacggga aacuuuaguu     1080

cgcccgagua cccuaacggc uacucggcgc acaugcacug cgucuggcga auaucgguaa     1140

cuccggggga gaagauuauu uuaaauuuca cuucauugga uuuauauagg ucgcgauuau     1200

guugguacga cuacguagaa guaagggacg gguuuuggcg uaaggccccu uugcgugggc     1260

gauucugcgg aucgaaguua ccggagccga uaguaaguac ggacucgcgu uuauggguag     1320

aguuccgaag uucgaguaac uggguaggua aggguuucuu cgccguuuac gaggcaauau     1380

gcggugggga cguaaagaag gacuacgguc auauacaguc uccgaauuac ccggacgacu     1440

acaggccuag uaagguaugu auauggcgca uccaagucuc ggagggauuc cauguugggu     1500

ugacguuuca gaguuucgag auagagaggc acgacucgug cgcguacgau uacuuagagg     1560

uaagggacgg acauucggag ucgaguacuu uaauaggacg auacugcggu uacgagaagc     1620

cggacgacau aaagucgacu ucgucgcgau ugugguuaaa guucguuucg gacggaagua     1680

uaaacaaggc agguuucgcg guuaacuucu uuaaggaggu agacgagugc ucgcgaccga     1740

accgaggcgg uugcgagcaa cgaugcuuaa acacguuggg aucuuacaaa ugcucuugcg     1800

acccggguua cgaguuggcg ccggauaaga ggcgaugcga ggcggcaugc ggggguuucu     1860

uaacaaaguu gaacgguucg auaacaucgc ccggguggcc gaaggaguac ccgccgaaca     1920

agaacugcau auggcaauua gucgcgccga cacaauaccg gauuucguua caguucgacu     1980

ucuucgagac ggaggguaac gacgucugua aguacgacuu cgucgagguc cgaucggguu     2040

ugacugcgga cucaaaguua cacgguaagu ucugcggcuc ggagaagccg gagguaauua     2100

caucgcagua caacaacaug cgagucgagu ucaagucgga caacacggua aguaagaagg     2160

gguucaaggc acacuucuuc ucggauaagg acgaguguuc gaaagacaac ggggguugcc     2220

aacaggacug cguaaacacc uucgguucgu acgaguguca gugccgaucg gguuucguau     2280

uacacgacaa caagcacgac ugcaaggagg caggaugcga ccauaagguc acgucgacuu     2340

cggggacgau aacgucgccg aacuggccgg acaaguaccc gucgaagaag gagugcaccu     2400

gggcgaucuc gucaacuccg ggucaucgag uuaaguugac guucauggag auggauauug     2460

agucgcagcc cgagugcgcg uacgaccacu uagagguauu cgacgggcgu gacgcgaaag     2520

caccgguauu aggaagguuc ugcgguucga agaaacccga accgguuuug gcgacgggaa     2580

gucguauguu cuuacgguuc uacucggaca auaguguaca acguaagggg uuccaagcau     2640

cgcaugcgac ggagugcggu ggucaggucc gagcggacgu uaaaacgaaa gacuuauacu     2700

cgcacgcgca guucggggac aauaacuacc cgggcggggu ugacugcgag uggguuauag     2760

ucgcagagga gggguacggu guagaguuag uauuccagac uuucgagguc gaggaggaga     2820

cggacugcgg uuacgacuac auggaguuau ucgacgguua cgacucgacg gcgccacgau     2880

uagguaggua cugcgggucg ggaccgccgg aggagguaua cucagccggu gacaguguau     2940

uagucaaguu ucacucugac gacacgauaa cgaagaaggg cuuccacuua cguuacacga     3000

guacgaaguu ccaggacacg uuacacucuc gaaagugagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  5755
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt10)

<400>  5755
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgcgggca cgagguguuu guuggcacuc uuauugccgc      120

aaguauuguu agggggggcc gcgggguugg uccccgaguu agggaggcgc aaguucgccg      180

ccgcaagcag cgggaggccg agcagucagc cgagcgacga gguauuaucg gaguucgagc      240

ucagauuauu gucgauguuc ggguuaaaac aacgcccgac gccgucgcgc gacgcggucg      300

ucccgccgua uauguuggac uuauauaggc gccacagcgg gcagcccggg agcccggcgc      360

cggaccacag acucgagcgc gcggcgucga gggcgaacac ggucaggucg uuccaccaug      420

aagaaagccu cgaagaauug ccggaaacau cgggcaaaac gacgagacgc uucuucuuua      480

aucucucgag cauaccgacc gaggaguuua uaacgagcgc cgaguugcaa gucuucaggg      540

aacagaugca agaugcgcuc gggaacaauu cgucguucca ucacaggaua aauauauaug      600

aaauaauuaa accggccacg gcgaacagca aauucccggu cacgcgcuug cucgacacgc      660

gccucgucaa ucagaaugcg ucgcgcuggg aaucguuuga uguaacgccg gcggucauga      720

gauggaccgc ccaggggcac gcgaaccaug gguucgucgu cgaagucgcg caccucgagg      780

agaaacaagg gguaaguaag cgccaugucc gcauuucgcg cagccuccac caagaugaac      840

acucguggag ccagauucgc ccgcucuugg ucacguuugg gcaugauggg aaaggccauc      900

cguugcacaa acgcgaaaaa aggcaagcga aacacaaaca aagaaaaagg uugaagaguu      960

cguguaagcg ccacccgcuc uacgucgacu ucucggacgu cgguuggaau gacuggauag     1020

ucgccccgcc uggcuaucac gcguuuuauu gccacgggga augcccguuu ccguuagccg     1080

aucauuuaaa caguacgaau caugcgauag uccagacacu cguaaacagc gucaacagca     1140

agauaccgaa agcgugcugu guacccacgg aauugucggc gauaagcaug uuauauuugg     1200

acgagaauga aaaggucguc cucaaaaauu aucaggacau ggucgucgag ggguguggcu     1260

guaggugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  5756
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt10)

<400>  5756
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaccgggaa acaggauguu aaugguagua uuguugugcc      120

agguauuauu ggguggugcc ucgcacgcga guuugauccc ggagaccggu aagaagaagg      180

uagcggagau ccagggccac gcggggggcc gacguagcgg ucagucgcac gaguuauugc      240

gagacuucga ggccacgcuc uuacagaugu ucggucuucg ccgaaggccg cagccgucua      300

agucggccgu cauacccgac uacaugcgag acuuauaccg auuacagucg ggcgaggagg      360

aggaggagca gauccacagu acgggguuag aguacccgga gcguccggcc ucgcgagcga      420

acacgguccg cucguuccac cacgaggagc acuuggagaa cauaccgggc accucggaga      480

acagugcguu cagauucuua uucaacuuau cgaguauccc agagaacgag gugauaucua      540

gugcggaguu gcgcuuauuc cgugagcagg uugaccaagg gccggacugg gagcgcggcu      600

uccaccgaau caacaucuac gaggugauga agccgccggc ggagguagua cccggucacu      660

uaaucacucg ucucuuagac acgcgauuag uacaccacaa cguaacgagg ugggagacgu      720

ucgacgucag uccggcggua uugaggugga cgcgcgagaa gcagcccaac uacggauuag      780

cgaucgaggu cacgcaccua caccagaccc guacgcacca gggccagcac guccgaauau      840

cgcgaucgcu accgcaggga ucggguaacu gggcgcaauu aagaccguug uuaguaacgu      900

ucggccacga cgggcgaggc cacgcuuuaa cgcgucgacg acgugcgaag cgcucgccga      960

agcaccacuc gcagcgagcg cgaaagaaga acaagaacug ccgacgucac agucuuuacg     1020

uugacuucuc ggacgucgga uggaacgacu ggauaguugc gccgccgggc uaccaggcgu     1080

ucuacugcca cggggacugc ccguucccgu uagccgacca cuuaaacagu accaaccacg     1140

ccaucgucca gacgcuugua aacucgguaa acaguucaau acccaaggcg ugcugcguac     1200

ccacggaguu aagugcgauc ucgauguuau acuuggacga guacgacaag guuguuuuaa     1260

agaacuacca ggagaugguu guggagggcu gcggaugccg uugaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  5757
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt10)

<400>  5757
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcuuag gcagacgcgc ccaaugguua uguugguggu      120

ggggcuuauu auguucgugu uguggcccgc cccccuuaag acccccgcuc ccggccgcgg      180

ccgcggcggc ggcgggcggc caauuauuag gcgauggggg cucgccgggg aggaccgaac      240

aacccccccc cagcccccaa aguaguagcg gguuuuuaua uagaagauug aaaacccaag      300

aaaaaagaga aaugcaaaaa gaaauacuca gcgucuuagg cuugccccau agaccgagac      360

cguuacaugg guugcagcaa ccccaaccgc ccgccuugag acaacaagaa gaacaacaac      420

aacaacaaca auuaccgagg ggggaaccgc cgccgggcag guuaaaaagu gccccguugu      480

uuauguuaga cuuauauaau gcguuaagug cggauaauga ugaagauggc gccagcgaag      540

gcgaacgcca acaaaguugg ccgcaugagg ccgcgucgag cagucaaagg agacaacccc      600

cgcccggggc ggcccauccc uugaauagga aaucguuguu agcgccgggg agcgggucgg      660

ggggggccag uccguuaacg ucggcccaag auucggcguu uuugaaugau gccgauaugg      720

ugaugucguu cgucaauuua gucgaauaug auaaagaauu uaguccgagg caaaggcauc      780

auaaggaauu uaaauuuaau cucagucaaa ucccggaagg ggaagucguc accgccgccg      840

aguuuaggau auauaaagau ugcgucaugg gcucguucaa gaaucagacc uucuugauau      900

cgaucuacca ggugcuccaa gaacaccaac aucgcgauag cgauuuauuc cuccucgaua      960

cgagggucgu cugggcgagc gaggaggggu gguuagaguu cgauauaacc gcgaccucga     1020

acuuaugggu cgucaccccg caacacaaua ugggcuugca auuaucgguc gucacccgcg     1080

acggggugca ugugcauccg agggcggccg gguuagucgg gcgcgauggg ccguaugaua     1140

aacaaccguu uauggucgcc uuuuuuaagg ucucggaagu ccaugucagg acgacgcgca     1200

gcgcgaguuc gagaaggagg cagcaaucga ggaacaggag cacgcaaagu caagaugucg     1260

ccagagugag uucggccagc gacuauaauu cgucggagcu caagaccgcg ugucgcaaac     1320

acgaauuaua cgucucguuu caggauuuag gguggcaaga uuggauaauc gccccgaaag     1380

gguacgccgc gaacuauugc gacggggagu guaguuuucc guugaaugcc cauaugaacg     1440

ccacgaauca ugccaucguc caaacgcucg uccauuugau gaauccggaa uacgugccga     1500

agcccuguug cgccccgacc aaauugaacg cgauaagcgu cuuguauuuc gacgauaaua     1560

guaacgugau cuuaaagaag uaucgcaaca uggucguccg cgccugcggg ugucauugag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  5758
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt10)

<400>  5758
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacguaagau cguuacgagc ggcggcuccg cacaguuucg      120

uagcguugug ggccccguua uucuuauugc gaucggcguu agcggacuuc aguuuagaca      180

acgagguaca cucgaguuuc auacaccgaa gauugcgcuc gcaggagagg cgcgagaugc      240

agcgagagau auuaaguaua uuaggguugc cgcaccgacc caggccccac uugcagggga      300

agcacaacuc ggcuccaaug uucauguuag acuuauacaa cgcgauggcg guagaggagg      360

gggggggucc cgggggucag ggcuucaguu accccuacaa ggcgguauuc ucuacgcagg      420

guccgccguu agcgaguuua caggacucgc acuucuugac ggacgcggac augguaauga      480

guuucguaaa cuuaguagag cacgacaagg aguucuucca cccgcgauac caccacaggg      540

aguuccgauu cgacuuaucg aagauacccg agggggaggc gguaacggcg gcggaguuca      600

ggauauacaa ggacuacauc cgagagagau ucgacaacga gacguuccga auaaguguau      660

accagguauu gcaggagcac uuagguaggg agucggacuu auucuuguua gacagucgca      720

cguuaugggc gucggaggag gguugguugg ucuucgacau aacggcgacg aguaaccacu      780

gggucguaaa ccccaggcac aacuuagguu uacaguuguc gguagagaca uuagacgguc      840

agucgauaaa cccgaaguua gccggguuga ucggucgaca cggcccgcag aacaagcagc      900

cguucauggu agccuucuuc aaggcgacgg agguacacuu caggaguaua aggucgacgg      960

guaguaagca gcgaucgcag aacaggagua agacaccaaa gaaccaggag gcguuaagaa     1020

uggcgaacgu agcugagaac ucgaguucgg accagaggca ggcgugcaag aagcacgagu     1080

uauacguaag uuuccgcgac uugggguggc aggacuggau aauagcgccg gagggguacg     1140

cagcguacua cugcgagggu gagugcgcgu uccccuuaaa cucguacaug aacgcgacga     1200

accacgcgau aguacagacg uuaguacacu ucaucaaccc ggagacagua ccgaagccgu     1260

gcugcgcgcc gacgcaguug aacgcgauaa guguauuaua cuucgacgac ucgaguaacg     1320

uaaucuuaaa gaaguacagg aacaugguag uacgagcgug cgguugccac ugaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  5759
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt10)

<400>  5759
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggcgucgg ccgcguuacu augcuuauua cuuaccgccg      120

cggcguucuc gccgcagggc uuagcgcaac cgguagguau aaacaccagu acgacaugcu      180

gcuacagguu cauaaacaag aagaucccga agcagcgauu agagaguuac cgucguacga      240

cgagcucuca cugcccgcgu gaggcgguca uauucaaaac gaaguuagac aaggagauau      300

gcgcagaccc cacccagaag uggguacagg acuucaugaa gcacuuagac aagaagacgc      360

agacgccuaa guugugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  5760
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt10)

<400>  5760
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuauugaccu ugauaaucuu acucccgguc gucagcaagu      120

ucucguucgu cucguugagc gccccccaac auuggucgug cccggagggg accuuggccg      180

ggaacggcaa caguaccugc gucgggccgg ccccguuucu caucuuuagu cacgggaacu      240

cgauauuccg caucgauacc gaggggacga acuacgaaca gcucgucguc gacgccgggg      300

ugagcgucau aauggacuuc cacuacaacg aaaagcgcau auacuggguc gaccucgagc      360

gccaguugcu ccagcgcguc uucuuaaacg gcagccgcca ggaacgcguc ugcaacaucg      420

aaaagaacgu cagcgggaug gccaucaacu ggaucaacga ggaggucauc uggagcaacc      480

agcaagaggg gauaaucacc gucaccgaca ugaaggggaa caacagucau aucuugcucu      540

cggcccucaa guacccggcc aacgucgccg ucgacccggu cgagcgcuuc aucuucugga      600

gcagcgaagu cgccgggucg uuguaccgcg ccgacuugga cggggucggg gucaaagccu      660

uacucgaaac cagcgaaaag aucaccgccg ucagccucga cgucuuggac aaaagauuau      720

ucuggaucca auauaaucgc gaggggucga acagcuugau cuguaguugc gacuacgacg      780

gggggagcgu gcauaucucg aagcacccga cccaacacaa ccucuucgcc augaguuugu      840

ucggggauag gauauuuuac agcaccugga agaugaaaac caucuggauc gcgaauaagc      900

auaccgggaa agauaugguc cgcaucaauu ugcacagcag cuucgucccg uugggggagu      960

uaaaggucgu ccacccguug gcccagccga aagccgagga cgauaccugg gaaccggaac     1020

aaaaguugug uaagcuccgc aaggggaauu guucgucgac cgucugcggc caggauuugc     1080

aaagccaucu cuguaugugc gccgaagggu augcguuguc gagggauaga aaauauugcg     1140

aggacgucaa cgagugcgcc uucuggaacc acgggugcac cuugggcugc aagaauacgc     1200

cggggaguua cuauuguacc uguccggucg gguucgucuu auugccggac ggcaagaggu     1260

gccaccaguu ggucaguugc ccgaggaacg ucagcgagug uucgcacgau ugcgucuuaa     1320

ccagcgaggg gccgcucugc uuuugcccgg aggggagcgu cuuggaacgc gacggcaaga     1380

ccugcucggg gugcaguagc ccggacaacg gggggugcuc gcaauugugu gucccguugu     1440

cgccggucag uugggagugc gacuguuucc cgggcuacga uuugcaguua gacgagaagu     1500

cgugcgccgc cagcgggccg cagccguucc ucuuauucgc gaacagccag gacaucaggc     1560

auaugcacuu cgacgggacc gauuacggga ccuuauuguc gcaacaaaug gggauggucu     1620

acgcguugga ccacgauccg gucgagaaca aaaucuauuu cgcgcacacc gcguuaaaau     1680

ggaucgaacg cgccaacaug gacgggaguc aaagggagcg cuugaucgaa gagggggucg     1740

acgucccgga gggguuggcc gucgauugga ucgggaggcg cuuuuacugg accgaucgcg     1800

gcaagagcuu aaucgggcgc ucggaccuca acggcaagag gaguaagauc auaaccaaag     1860

aaaauauaag ccagccgagg gggaucgccg uccacccgau ggcgaaacgc cucuuuugga     1920

ccgacaccgg caucaacccg aggaucgagu cgagcaguuu gcagggguug gggagguuag     1980

ucaucgcguc gagcgacuug auauggccgu cggggaucac caucgauuuu cucaccgaua     2040

aacucuauug gugugacgcg aaacaaagcg ucaucgagau ggcgaacuua gacgggagca     2100

agaggaggcg cuugacgcaa aacgacgucg ggcauccguu cgccgucgcc gucuucgaag     2160

acuacgucug guuuagcgac ugggccaugc cgagcgucau gcgcgucaau aaacgcaccg     2220

ggaaggaccg cgucagguug caggggucga uguuaaaacc gagcagcuua gucgucgucc     2280

acccgcucgc caagccgggg gccgacccgu gucucuacca gaaugggggg ugcgagcaca     2340

ucuguaagaa acgcuugggg accgccuggu gcagcugcag ggagggguuc augaaggcga     2400

gcgacggcaa gaccugcuua gccuuagacg ggcaccaauu acucgccggg ggggaggucg     2460

acuugaaaaa ucaggucacc ccgcucgaua uacucaguaa aacccgcguc agcgaggaca     2520

auaucaccga gagccagcau auguuggucg ccgagauaau ggucagcgac caggacgauu     2580

gcgccccggu cggguguucg auguacgcca gaugcaucag cgaaggggaa gacgcgaccu     2640

gccaaugccu caagggguuc gccggcgacg ggaaguugug cagcgacauc gacgagugcg     2700

aaaugggggu gccggucugu ccgccggcga guaguaaaug uauaaauacg gagggggggu     2760

acguguguag auguagcgag ggguaucagg gggacggcau ccauugcuug gacaucgacg     2820

aaugucaguu aggcgaacau ucgugcgggg aaaacgcguc guguaccaac accgaagggg     2880

gguacacgug uaugugcgcc gggagguuaa gcgagccggg guuaaucugu ccggauagca     2940

ccccgccgcc gcauuugcgc gaggacgauc aucauuacag uguccgcaac ucggauagcg     3000

agugcccguu aagucaugac ggcuauuguu ugcacgacgg ggucuguaug uacaucgagg     3060

cccucgauaa auacgccugu aauugcgucg ucggguauau aggcgaaagg ugccaauaua     3120

gggauuuaaa auggugggag uuaaggcaug ccgggcaugg ccaacaacaa aaagugauag     3180

ucgucgccgu gugugucguc gucuugguga uguuauuguu guuaucguua uggggcgcgc     3240

auuauuaucg cacccaaaaa uuauugagca agaauccgaa aaacccguac gaagaaagcu     3300

cgcgcgacgu ccgcucgagg cgcccggccg auaccgaaga cggcaugagu agcuguccgc     3360

agccgugguu cgucgucauc aaggagcauc aggauuugaa aaacggcggg cagccggucg     3420

ccggggaaga cgggcaagcc gccgacggca gcaugcagcc gaccagcugg cgccaagaac     3480

cgcaacucug cgggaugggg accgaacagg gguguuggau cccggucagu ucggacaaag     3540

ggaguugccc gcaagucaug gaaaggucgu uccacaugcc gaguuacggc acccaaacgu     3600

uggagggcgg gguggaaaaa ccgcacagcu uguugagcgc caauccgcuc uggcagcagc     3660

gcgcguuaga uccgccgcau cagauggaau uaacccaaug aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  5761
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt10)

<400>  5761
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acggccggcc gccgcaugga aauguugugc gcggggcgcg      120

ugccggccuu auuauugugu uuaggguuuc acuuguugca agccguguug ucgaccaccg      180

ucaucccgag cugcauaccg ggggaaaguu cggacaauug uaccgcccuc guccaaaccg      240

aggauaaccc gagggucgcc caggucagca ucaccaaaug cucgagcgau augaacgggu      300

acugccucca cgggcaaugu auauacuuag ucgauauguc gcagaauuau ugucgcugcg      360

aggucgggua caccggggug aggugcgagc auuuuuuccu cacggugcau cagccgcucu      420

cgaaggagua cgucgcccuc acggucaucu ugaucauccu cuucuugaua accguggugg      480

ggaguaccua cuacuuuugu cgcugguauc gcaacaggaa gucgaaggag ccgaaaaaag      540

aguacgaacg cgucacgagc ggcgacccgg aacuccccca ggugugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  5762
<211>  815
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt10)

<400>  5762
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcggagggug agauaacgac guucacugcg uuaacggaga      120

aguucaacuu accgccgggu aacuacaaga agcccaaguu guuauacugc ucgaacgggg      180

ggcacuucuu acgaauauua ccagacggca cgguagacgg uacccgagac cggucggacc      240

agcacaucca guuacaauua ucggcggaga guguuggcga gguauacauc aagucgacug      300

agacagggca guacuuggcg auggacacgg acggguuauu guacgggagu caaacgccga      360

acgaggagug cuuauucuua gagcgcuugg aggagaacca cuacaacacg uacaucucga      420

agaagcacgc ggagaagaac ugguucguag gguuaaagaa gaacgguagu ugcaagcggg      480

ggccacgcac gcacuacggu cagaaggcga ucuuauucuu gccguuacca guaucgagug      540

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      600

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      660

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      720

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 815


<210>  5763
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt10)

<400>  5763
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggcgucg ggggcgggga cguggaggac gugaccccgc      120

gcccgggcgg gugccagauc ucgggccggg gcgcccgcgg gugcaacggc auccccgggg      180

ccgcggccug ggaggccgcc cugccccggc gccggccccg ccggcacccg uccgucaacc      240

cccgcucgcg ggccgcgggc ucgccccgca cccgggggcg ccggacggag gagcgccccu      300

ccggcucccg gcucggcgac cgcgggcggg gccgcgcccu gcccgggggc cggcugggcg      360

ggcgcggccg ggggcgcgcc cccgagcgcg ugggcgggcg gggccgcggc cgggggaccg      420

ccgcgccccg cgccgccccc gccgcccggg gcucgcgccc ggggcccgcg ggcaccaugg      480

ccgccggguc caucaccacg cuccccgccc ugcccgagga cggcggcucg ggggccuucc      540

cgcccggcca cuucaaggac cccaagcggc uguacugcaa gaacgggggc uucuuccucc      600

gcauccaccc cgacgggcgg guggacggcg uccgcgagaa guccgacccg cacaucaagc      660

ugcagcugca ggcggaggag cggggcgugg ugucgaucaa gggggucugc gccaaccgcu      720

accucgccau gaaggaggac ggccggcugc uggccuccaa gugcgugacc gacgagugcu      780

ucuucuucga gcgccucgag ucgaacaacu acaacaccua ccggucccgc aaguacaccu      840

cgugguacgu ggccuuaaag cggacggggc aguacaaguu aggcuccaag accggccccg      900

ggcagaaggc gauccucuuc uuacccaugu cggccaaguc cugaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  5764
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt10)

<400>  5764
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uauuaacgug gauauugccg acguuauuau      120

acaggucgug cuuccacaua auaugcuugg ucgggacaau aaguuuagcg ugcaacgaca      180

ugacgcccga gcaaauggcg acgaacguaa auugcucgag uccggagaga cacacgaggu      240

cguaugacua uauggagggg ggcgacauaa gagucaggag auuauucugc aggacacaau      300

gguauuugag aauagacaag aggggcaaag ucaaggggac gcaagagaug aaaaacaacu      360

auaacauaau ggagauaaga acgguagccg ucggcauagu cgcgauaaaa gggguagaga      420

gugaguucua uuuagcgaug aacaaggagg ggaaguuaua ugcgaagaag gagugcaacg      480

aggacugcaa uuucaaggag uugauauuag agaaccacua uaacacguac gcgucggcca      540

aguggacaca caacggcggg gagauguucg ucgcguuaaa ccaaaagggc auaccgguca      600

gggggaagaa gacgaagaaa gagcaaaaga cggcgcacuu cuugccgaug gcgauaacgu      660

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  5765
<211>  974
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt10)

<400>  5765
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguuguuac ccucaguugu acucaaauua uucuuagcgg      120

ccguauuaag ugcucuugug accggcgagu cguuggagcg uuugcgccgc ggucuugcag      180

cgggcacgag uaacccggac ccgccgacgg ucucgaccga ccaguuacuc ccucucgggg      240

gcgggcgcga ccguaagguu cgggaccucc aggaggcgga cuuagaccuc cuacguguua      300

cgcuuucguc gaagccccag gccuuggcga ccccuaacaa ggaggagcac gguaagcgua      360

agaagaaggg gaaggggcuu ggcaagaagc gugacccgug cuugcgaaag uacaaggacu      420

ucugcauaca cggggagugc aaguacguca aggaguuacg agcgccgagu ugcaucugcc      480

acccgggcua ccacggggag cgaugccacg gcuugucguu accgguagag aaccguuugu      540

acacuuacga ccacacuacc auacucgccg uagucgcggu ugucuuaucg ucgguaugcu      600

uauuaguaau aguaggcuua uuaauguucc gauaccaccg acgcgggggc uacgacguag      660

agaacgagga gaaggugaag cuagggauga cgaacucgca cugaggacua gugcaucaca      720

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua      780

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu      840

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua      900

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaag aauu                                                        974


<210>  5766
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt10)

<400>  5766
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggucacga aguuguuacc ggcguuauua uuacaacacg      120

uguuguuaca cuuguuguua uugccgauag cgauaccgua ugccgaaggg cagcgcaagc      180

gccgcaauac cauccacgag uuuaagaaga gugccaaaac cacguugaua aagaucgacc      240

cggccuuaaa aaucaagacg aaaaagguca acaccgccga ucagugcgcc aaccgcugca      300

cccgcaacaa gggguugccg uuuaccugua aagccuucgu cuucgacaag gcccgcaagc      360

aauguuugug guuuccguuu aacucgauga gcucgggggu caagaaggag uucgggcacg      420

aguucgauuu guaugagaau aaggauuaua uccgcaauug uauaaucggg aaagggaggu      480

cguauaaagg gaccgucagc auaaccaaau cggggauaaa augccaaccg uggucgagua      540

ugaucccgca ugagcauucg uuccucccga gcucguacag agggaaggau uugcaagaga      600

auuauugcag gaacccgagg ggcgaggagg gcgggccgug gugcuuuacc ucgaacccgg      660

aagucaggua ugaggugugc gauaucccgc aaugcagcga ggucgagugu augacgugua      720

acggcgaauc guacaggggg uugauggacc acaccgagag cgggaaaauc ugccaaaggu      780

gggaccacca aaccccgcau agacauaaau uucucccgga gcgcuauccg gauaaagggu      840

ucgacgacaa cuacuguagg aacccggacg ggcaaccccg cccguggugu uauaccuugg      900

auccgcauac gaggugggaa uauugcgcca ucaaaaccug ugccgauaac accaugaacg      960

auaccgacgu cccgcucgag accaccgagu guauacaggg gcagggggag ggguaucgcg     1020

ggaccgugaa cacgaucugg aacgggaucc cgugccaaag gugggacagc caauauccgc     1080

augaacacga uaugaccccg gagaacuuua aauguaaaga uuugagggag aacuauugua     1140

ggaacccgga cggcagcgag agcccguggu gcuucacgac cgacccgaau auaagggucg     1200

gguauuguag ucagaucccg aauugcgaca ugagccacgg gcaagacugc uauaggggca     1260

acgggaaaaa cuacaugggg aaucucaguc agacccgcag cggguugacc ugcagcaugu     1320

gggauaaaaa uauggaggau cuccacaggc acauauuuug ggagccggac gccucgaaau     1380

uaaacgaaaa cuauuguagg aacccggacg acgacgccca cgggccgugg uguuauaccg     1440

ggaacccguu gaucccgugg gacuauuguc cgaucaguag gugcgagggg gacacgaccc     1500

cgaccaucgu gaaccucgau cacccgguca ucagcugcgc gaagaccaag cagcucaggg     1560

ucgucaacgg caucccgacc aggaccaaua ucggguggau ggucucgcuc cgcuaucgca     1620

acaagcacau augugggggg agccucauca aagaaucgug ggucuugacc gccaggcaau     1680

gcuuuccgag cagggaucuc aaggacuacg aggccugguu ggggauccac gacgugcaug     1740

ggcgcgggga cgaaaagugu aagcaagucu ugaacgucag ucaauuaguc uacgggccgg     1800

aggggagcga cuuaguccuc augaaauugg cgcgcccggc cguguuagac gacuucgucu     1860

cgaccaucga ccucccgaau uacgggugua ccaucccgga gaaaacgucg uguucggucu     1920

augggugggg guauaccggg cucauaaauu acgacggguu gcucaggguc gcccacuugu     1980

auaucauggg gaacgaaaag uguucgcaac accacagggg caaagucacc uuaaacgaaa     2040

gcgagaucug cgccggcgcc gagaaaaucg ggagcgggcc gugcgaaggc gacuaugggg     2100

ggccguuggu cugcgaacag cacaaaaugc gcauggucuu gggggugauc gucccgggga     2160

gggggugcgc gaucccgaac aggccgggga ucuucgugag ggucgccuac uacgccaagu     2220

ggauccauaa gaucauccuc accuauaaag ucccgcaaag cugaggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  5767
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt10)

<400>  5767
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgaaggcgg cggcaauagg gauagacuua gguacgacgu      120

acucgugcgu ugguguauuc cagcacggua agguagagau aauagcgaac gaccagggua      180

accggacgac gccgaguuac gucgcguuca ccgacacgga gcgcuugauc ggggacgccg      240

cgaagaacca gguagcuuua aacccacaaa acacgguuuu cgacgcaaag cgacucauag      300

ggcgaaaguu cggggacccc gucguacaau cagacaugaa gcacuggccg uuccagguca      360

uaaacgacgg ugacaagccg aagguccagg uaaguuacaa gggcgagacg aaggcguucu      420

acccugagga gaucucaagu augguauuga cgaagaugaa ggagauagcg gaggcauacu      480

uaggauaccc cgugacgaac gccguaauca cgguccccgc guacuucaac gacucucagc      540

ggcaggcgac gaaggacgca ggcguaaucg caggguuaaa cguauugcgc aucauaaacg      600

agccgaccgc ggcggcgaua gcauacgggu uagaccggac cgggaagggu gagcgaaacg      660

uauuaaucuu cgacuugggu ggggguacgu ucgacgucuc gauauuaacc aucgacgacg      720

gcauauucga gguaaaggcg accgccgggg acacgcacuu aggcggggag gacuucgaca      780

accgauuggu caaccacuuc guagaggagu ucaagcgaaa gcacaagaag gacauaucgc      840

agaacaagcg ugcgguaaga agguuacgaa cggcgugcga gcgggcuaag cgcacguuaa      900

guucgaguac gcaggcgucg uuggagauag acaguuuauu cgaggguaua gacuucuaca      960

cuucgauaac gcgugcacga uucgaggagu uaugcucgga cuuauucagg ucgacguuag     1020

agccgguaga gaaggcauua cgagacgcga aguuggacaa ggcacagaua cacgacuuag     1080

uauuaguagg ugguucgacg cggauaccga agguacagaa guuguuacag gacuucuuca     1140

acggucgaga cuuaaacaag ucgaucaacc cggacgaggc gguagcguac ggggccgcgg     1200

uacaggccgc gauauugaug ggugacaaga gugagaacgu acaggacuua uuauuauuag     1260

acguagcacc cuuaucuuug gguuuagaga ccgcgggugg ggucaugacg gcguuaauaa     1320

agcgaaacuc gacgaucccg acgaagcaga cccagaucuu cacuacguac ucggacaacc     1380

agccgggugu auugauccag guauacgagg gugagcgagc gaugaccaag gacaacaacu     1440

uauuaggacg uuucgaguug ucggguauac cgcccgcacc ucgagggguc ccgcagaucg     1500

aggucacguu cgacaucgac gcgaacggua ucuuaaacgu aacggcgacc gacaaaagua     1560

cggggaaggc caacaagauc acgauaacga acgacaaggg ucgauuaucg aaggaggaga     1620

uagagaggau gguccaggag gcagagaagu acaaggccga ggacgagguc cagagagagc     1680

gaguaagugc gaagaacgcg uuggagucgu acgcguucaa caugaagagu gcggucgagg     1740

acgaggguuu aaaggguaag aucucggagg ccgacaagaa gaaggucuua gacaagugcc     1800

aggagguuau aucuugguua gacgcgaaca cguuagcgga gaaggacgag uucgagcaca     1860

agcgcaagga guuagagcag guaugcaacc cgauaauauc ggguuuguac cagggggcgg     1920

gcgggccggg uccggguggu uucggcgcgc agggaccgaa gggugguagu gggucggguc     1980

cgacgaucga ggagguagac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  5768
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt10)

<400>  5768
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgaaggcgg cggcaauagg gauagacuua gguacgacgu      120

acucgugcgu ugguguauuc cagcacggua agguagagau aauagcgaac gaccagggua      180

accggacgac gccgaguuac gucgcguuca ccgacacgga gcgcuugauc ggggacgccg      240

cgaagaacca gguagcuuua aacccacaaa acacgguuuu cgacgcaaag cgacucauag      300

ggcgaaaguu cggggacccc gucguacaau cagacaugaa gcacuggccg uuccagguca      360

uaaacgacgg ugacaagccg aagguccagg uaaguuacaa gggcgagacg aaggcguucu      420

acccugagga gaucucaagu augguauuga cgaagaugaa ggagauagcg gaggcauacu      480

uaggauaccc cgugacgaac gccguaauca cgguccccgc guacuucaac gacucucagc      540

ggcaggcgac gaaggacgca ggcguaaucg caggguuaaa cguauugcgc aucauaaacg      600

agccgaccgc ggcggcgaua gcauacgggu uagaccggac cgggaagggu gagcgaaacg      660

uauuaaucuu cgacuugggu ggggguacgu ucgacgucuc gauauuaacc aucgacgacg      720

gcauauucga gguaaaggcg accgccgggg acacgcacuu aggcggggag gacuucgaca      780

accgauuggu caaccacuuc guagaggagu ucaagcgaaa gcacaagaag gacauaucgc      840

agaacaagcg ugcgguaaga agguuacgaa cggcgugcga gcgggcuaag cgcacguuaa      900

guucgaguac gcaggcgucg uuggagauag acaguuuauu cgaggguaua gacuucuaca      960

cuucgauaac gcgugcacga uucgaggagu uaugcucgga cuuauucagg ucgacguuag     1020

agccgguaga gaaggcauua cgagacgcga aguuggacaa ggcacagaua cacgacuuag     1080

uauuaguagg ugguucgacg cggauaccga agguacagaa guuguuacag gacuucuuca     1140

acggucgaga cuuaaacaag ucgaucaacc cggacgaggc gguagcguac ggggccgcgg     1200

uacaggccgc gauauugaug ggugacaaga gugagaacgu acaggacuua uuauuauuag     1260

acguagcacc cuuaucuuug gguuuagaga ccgcgggugg ggucaugacg gcguuaauaa     1320

agcgaaacuc gacgaucccg acgaagcaga cccagaucuu cacuacguac ucggacaacc     1380

agccgggugu auugauccag guauacgagg gugagcgagc gaugaccaag gacaacaacu     1440

uauuaggacg uuucgaguug ucggguauac cgcccgcacc ucgagggguc ccgcagaucg     1500

aggucacguu cgacaucgac gcgaacggua ucuuaaacgu aacggcgacc gacaaaagua     1560

cggggaaggc caacaagauc acgauaacga acgacaaggg ucgauuaucg aaggaggaga     1620

uagagaggau gguccaggag gcagagaagu acaaggccga ggacgagguc cagagagagc     1680

gaguaagugc gaagaacgcg uuggagucgu acgcguucaa caugaagagu gcggucgagg     1740

acgaggguuu aaaggguaag aucucggagg ccgacaagaa gaaggucuua gacaagugcc     1800

aggagguuau aucuugguua gacgcgaaca cguuagcgga gaaggacgag uucgagcaca     1860

agcgcaagga guuagagcag guaugcaacc cgauaauauc ggguuuguac cagggggcgg     1920

gcgggccggg uccggguggu uucggcgcgc agggaccgaa gggugguagu gggucggguc     1980

cgacgaucga ggagguagac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  5769
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt10)

<400>  5769
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgacggcga aggguauagc uauagguaua gacuuaggaa      120

cgacauacuc gugcguaggu gucuuccagc acgggaaggu cgagaucaua gcuaacgacc      180

aggggaacag gacaacgccg aguuacgucg cguucaccga cacugagaga uugaucggug      240

acgcggcgaa gaaccagguc gcgaugaacc cucaaaacac gguauucgac gcgaagcggu      300

uaaucggucg caaguucaac gacccggucg uucaggcgga caugaaguua uggccguucc      360

aaguaauaaa cgagggcgga aagccgaagg uauugguauc guacaagggu gagaacaagg      420

cauucuaccc ggaagagaua aguucgaugg uuuuaaccaa guuaaaggag acagcggagg      480

cguucuuagg ucauccggua acuaacgcgg uaaucacggu acccgcuuac uucaacgaca      540

gucagcggca ggcgacgaag gacgcggggg ucauagcggg uuuaaacgua uuacgcauaa      600

uaaacgagcc aacggcagcg gcgauagcgu acggucuuga caagggggga cagggugagc      660

ggcacguauu aaucuucgac uuagguggcg guacauucga cgucucgaua uugacgaucg      720

acgacgguau auucgaggua aaggcgacgg cgggugacac gcacuuaggu ggugaggacu      780

ucgacaacag auuaguaagu cacuucgucg aggaguucaa gcggaagcac aagaaggaca      840

uaucgcaaaa caagcgcgcu guaaggagau ugcggacggc cugcgagcgc gcgaagcgga      900

cguuaaguuc gucgacgcag gcgaaccucg agauagacuc guuguacgag gguauagacu      960

uuuacacgag uaucacgcga gcgagauucg aggaguuaug cgccgacuua uuccgcggga     1020

cauuggagcc cguugagaag gcguuaaggg acgcgaagau ggacaaggcg aagauccacg     1080

acauaguauu agucgguggu ucgacccgaa uaccgaaggu acagcgguua uuacaagacu     1140

acuucaacgg ucgcgacuug aacaagucga uaaacccgga cgaggcggua gcguacgggg     1200

cggcagucca ggcggcgaua uuaauggggg acaagucgga gaagguccaa gacuuauuau     1260

uguuggacgu ugcgccguua aguuuagguu uagagacugc gggcggugua augacggcgu     1320

uaaucaagcg gaacucgaca auaccaacga agcagacgca aauauucacu acguacagug     1380

acaaccagcc ggguguauug auacagguau acgaggguga gcgggcgaug acgaaggaca     1440

acaacuuauu aggucguuuc gacuuaacug guauaccucc ggcuccgcgg gggguaccgc     1500

aaauagaggu cacguucgac auagacgcga acgggaucuu aaacguaacg gcgaccgaca     1560

agucgacagg uaagguuaac aagauaacua uaacgaacga caaggguaga uuaucgaagg     1620

aggagaucga gaggaugguc uuggacgcgg agaaguacaa ggcagaggac gagguacaga     1680

gagaaaagau agcggcgaag aacgcguuag agaguuacgc guucaacaug aagucgguag     1740

uaucggacga gggauuaaag gguaagaucu cggagaguga caagaacaag auauuagaca     1800

agugcaacga guuauuaucg ugguuggagg uuaaccaguu agcggagaag gacgaguucg     1860

accauaagag gaaggaguua gagcaaaugu gcaacccgau caucacgaag uuauaccagg     1920

gggguugcac ggguccggcg ugcgguacgg guuacguccc ugggcgaccg gcaacagguc     1980

cgacgauaga ggagguagac ugaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  5770
<211>  2267
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt10)

<400>  5770
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucggccaggg ggccggccau agggaucgau uuggggacga      120

cguauagcug ugucgggguc uuucaacaug ggaaggugga gaucauagcc aaugaucagg      180

gcaaucgcac gaccccgagu uacgucgcgu ucaccgauac ggagagguug auaggggaug      240

ccgcgaaaaa ucaagucgcc augaauccga ccaauaccau auuugaugcc aaacgcuuga      300

uagggaggaa auuugaggau gccaccgugc agucggauau gaaacauugg ccguuuaggg      360

ucgucaguga gggggggaag ccgaaaguac agguggagua uaagggggaa accaaaacgu      420

ucuuuccgga ggaaauaagc ucgauggucu ugacgaagau gaaggagauc gccgaagccu      480

acuugggggg gaaagugcau ucggccguca ucaccgugcc ggccuauuuc aaugauucgc      540

agcgccaggc caccaaggau gccgggacga ucaccggguu gaauguguug aggaucauaa      600

acgagccgac cgccgccgcc auagccuaug gguuggauaa aaaggggugu gcgggggggg      660

aaaagaaugu guugaucuuu gauuuggggg gcgggaccuu ugaugugagc aucuugacga      720

ucgaggaugg gauauuugaa gugaagucga ccgcggggga uacccauuug gggggcgagg      780

auuuugauaa uaggaugguc ucgcacuugg cggaggaauu uaagcgcaaa cauaaaaagg      840

acaucgggcc gaauaagaga gccguccgcc gcuugcgcac ggccugugag agagccaagc      900

gcacguuguc gagcucgacc caggccucga ucgagauaga uaguuuguau gagggcgucg      960

auuuuuauac gagcauaacc agagcgaggu ucgaagaguu gaaugcggac uuauuuaggg     1020

ggaccuugga gccgguggag aaggccuuga gggaugccaa gcucgauaag gggcagaucc     1080

aggagaucgu guuagugggg gggaguacga ggauaccgaa gauacagaag uuguugcagg     1140

auuuuuuuaa uggcaaggag uugaauaaga gcaucaaucc ggacgaggcc guggcguaug     1200

gggccgccgu ccaggccgcc aucuugauag gcgauaaguc ggaaaaugug caggauuugu     1260

uguuauugga ugucacgccg uugagcuugg gcaucgaaac cgccgggggg gucaugacgc     1320

cguuaaucaa gaggaauacc acgaucccga ccaagcaaac gcaaacguuu accacguauu     1380

cggauaauca aagcaguguc uuggugcaag ucuaugaagg ggagagggcc augaccaagg     1440

auaauaauuu gcucgggaaa uuugauuuga ccgggauccc cccggccccg aggggggucc     1500

cgcagauaga ggugaccuuc gauaucgaug cgaaugggau auugaauguc acggccgcgg     1560

auaagucgac cggcaaagag aauaaaauaa ccaucaccaa ugauaagggc cgcuuaucga     1620

aggaugauau cgauaggaug gugcaggagg ccgagaggua uaagagcgag gacgaagcca     1680

aucgcgauag gguggccgcc aaaaaugccu uagagagcua uacguauaau auaaaacaaa     1740

cgguggagga ugagaaguua agggggaaga ucucggagca ggauaagaau aagaucuuag     1800

auaagugcca ggaggugauc aauugguugg auaggaauca gauggcggag aaggaugagu     1860

augagcauaa gcagaaggag uuggagaggg ucuguaaucc gaucauaagc aagcucuauc     1920

agggggggcc gggggggggc ucgggggggg gggggagugg ggccucgggg gggccgacga     1980

uagaggaggu cgacugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2040

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2100

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2160

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2267


<210>  5771
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt10)

<400>  5771
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucagucguag guaucgaccu cgguuuucaa aguuguuacg      120

uagcgguagc gcgagcugga gguauagaga cgauagcaaa cgaauacucg gaccgaugca      180

cuccugcgug cauaucguuc gggccgaaga acaggucgau aggggccgcg gcaaagucgc      240

agguuaucuc aaacgcgaaa aacacgguac aggguuucaa gcgauuucac ggucgugcgu      300

ucucggaccc uuucgucgag gccgagaaga guaacuuagc guacgacaua guucaauuac      360

cgacgggucu cacgggcauu aagguaacuu acauggaaga ggagcgcaac uucacuacgg      420

agcagguaac ggcgauguug uuaucgaagu uaaaggaaac ggcagagucg guauuaaaga      480

agccaguggu agacugcgua guaucaguac cgugcuucua cacggacgcg gagcggcguu      540

cgguuaugga cgccacgcag auagcggggc ucaacuguuu acgccuaaug aacgagacga      600

cggccguagc guuagcguac gggauuuaca agcaggacuu gccagcgcuu gaggagaagc      660

cgcgcaacgu uguauucgug gacaugggac acucggcaua ccaggugucg gucugcgcgu      720

ucaaccgggg gaagcucaag gucuuagcga cggcguucga caccacguua ggcggacgca      780

aguucgacga gguacucguu aaccacuucu gcgaggaguu cgguaagaag uauaaguuag      840

acauaaaguc gaagauucga gcguugcuuc guuuaucgca ggagugcgag aaguuaaaga      900

aguuaauguc agcgaacgcg ucggacuugc cccuuucgau cgagugcuuc augaacgacg      960

uagacguuuc agggaccaug aacaggggga aguucuuaga gauguguaac gacuuauugg     1020

cacgagucga accucccuug aggucggucu uagagcagac aaaguugaag aaggaggaca     1080

uauacgcggu agagaucguc ggaggggcaa cgcguauucc ggcaguuaag gagaagauau     1140

cgaaguucuu cggcaaggag uuaucgacga cgcuuaacgc ggacgaggcg guaacgaggg     1200

guugcgcguu acagugcgcu auacuuucuc cagcguucaa gguacgcgag uucucgauaa     1260

cggacguugu uccguacccc aucaguuuac gguggaacuc gccggcggag gaggguucgu     1320

cggacugcga gguguucucg aagaaccacg cggcgcccuu cucgaagguc uuaacguucu     1380

accgaaaaga gccguucaca uuagaggcau acuacaguuc gccacaggac cuuccuuacc     1440

cggacccggc gaucgcacag uucucgguac aaaagguuac gccccagucg gacgguucgu     1500

cgucgaaggu caagguaaag gugaggguua acguucacgg uaucuuuucg gucaguucgg     1560

cgucgcuugu agagguccac aagucggagg agaacgagga gccgauggag acggaccaga     1620

acgcgaaaga ggaggagaaa augcagguag accaggagga gccgcacgua gaggagcagc     1680

aacagcagac gccggcggag aacaaggcgg agucggagga gauggagacu ucgcaggcgg     1740

gcucgaagga caagaaaaug gaccagccuc cgcaggcgaa aaaggcgaag gucaagacau     1800

cuaccgucga cuuaccgaua gagaaccagu uauuguggca aaucgaccga gagauguuaa     1860

acuuauacau cgagaacgag gggaaaauga ucaugcagga caaguuggaa aaggagcgca     1920

acgacgcgaa aaacgcgguu gaggaguacg uuuacgagau gcgugacaag uuaucgggcg     1980

aguacgagaa guucgucucg gaggacgacc gaaacucauu cacguuaaag uuggaggaca     2040

cggagaacug guuauacgag gacggggagg accaaccgaa gcagguauac gucgacaagc     2100

uagcggagcu uaagaacuug ggacagccca uaaagaucag guuccaagag agugaggagc     2160

gcccgaagcu auucgaggag uuagguaagc aaauacagca guacaugaag aucauaucua     2220

guuuuaagaa caaggaggac caauacgacc acuuagacgc ggcagacaug acuaaggucg     2280

agaagaguac gaacgaggcg auggagugga ugaacaauaa guuaaacuua caaaacaagc     2340

agucguuaac gauggacccg guaguaaagu cgaaggagau cgaggccaag aucaaggagu     2400

uaaccucuac augcucgcca aucauaucga agccgaagcc gaagguagag ccgccgaagg     2460

aggagcagaa gaacgccgag caaaacggcc ccguagacgg ucagggugac aaccccgggc     2520

cucaggcggc agaacagggg acggacaccg cgguaccguc ugacucggac aaaaaguuac     2580

cggagaugga caucgacuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  5772
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt10)

<400>  5772
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgucgucg ggaucgauuu gggguucuug aauuguuaua      120

uagccguggc ccgcucgggg gggauagaaa cgauagcgaa cgaauauucg gaucgcugua      180

cgcccgcgug caucagccuc gggagccgca ccagggcgau agggaacgcc gccaaaucgc      240

aaaucgugac caauguccgc aacaccaucc acggguuuaa gaaauugcac ggcaggagcu      300

ucgacgaucc gaucguccag accgagcgca uacgcuugcc guacgaauua caaaagaugc      360

cgaacggguc ggccgggguc aaagucagau aucucgaaga ggaacgcccg uucgccaucg      420

aacaagucac cgggauguua cucgcgaaau ugaaggaaac cagcgagaac gcccucaaaa      480

agccggucgc cgauugcguc aucagcaucc cgucguuuuu caccgacgcg gaacgccgca      540

gcgucauggc cgccgcgcaa gucgccgggc ucaacugccu ccgccucaug aacgagacca      600

ccgccgucgc cuuagccuac gggaucuaca agcaagacuu gccgccgcuc gacgaaaagc      660

cgcgcaacgu cgucuucauc gacauggggc auagcgcgua ccaagugcuc gucugcgccu      720

uuaauaaagg gaaguugaag gugcucgcca ccacguucga cccguaccuc ggggggcgca      780

auuucgacga agcccucguc gauuauuuuu gcgacgaauu uaaaacgaag uacaaaauca      840

acgucaagga gaauagcaga gcgcuccuca ggcucuacca agaaugcgag aaguugaaaa      900

aauugauguc ggccaacgcc agcgacuugc cgcucaauau cgaaugcuuu augaacgauu      960

uggacgucag cucgaagaug aaucgcgccc aguucgaaca auuaugcgcc aguuugcucg     1020

cgcgcgucga gccgccgcuc aaagccguca uggagcaagc caaucuccaa agggaggaua     1080

ucucgucgau cgagaucguc gggggggcca ccaggauccc ggccgucaag gagcaaauaa     1140

ccaaguuuuu cuugaaggau aucucgacga cccucaacgc cgacgaggcc gucgcccgcg     1200

ggugcgcccu ccaaugcgcc aucuugagcc cggccuucaa ggucagggag uucaguauca     1260

ccgauuuggu cccguacagc auaacccucc gcuggaaaac gagcuucgag gacgggucgg     1320

gcgagugcga ggucuuuugc aaaaaucauc cggcgccguu uagcaaagug aucaccuuuc     1380

auaaaaaaga gccguucgag uuggaggccu ucuacaccaa ccuccaugag gucccguauc     1440

cggacgcccg caucggcucg uuuaccaucc aaaacgucuu cccgcaaagc gacggggacu     1500

cgaguaaggu caaagucaag gucaggguca auauacacgg gauauuuucg gucgccucgg     1560

ccagcgucau cgaaaaacag aaccucgagg gggaccauuc ggacgccccg auggaaaccg     1620

agaccagcuu caagaacgag aauaaggaca acauggacaa gaugcaaguc gaccaagagg     1680

agggccacca gaagugccac gccgagcaua ccccggagga agagaucgac cauaccgggg     1740

cgaagaccaa aagcgccgug agcgauaagc aagauaggcu caaccaaacc uugaagaagg     1800

ggaaaguaaa gucgaucgac uugcccauac aaucgucguu gugccgccaa uuggggcaag     1860

acuuguuaaa uucguauauc gagaacgaag gcaaaaugau aaugcaagac aaacucgaaa     1920

aggagcgcaa cgacgccaaa aacgcggucg aggaguacgu cuacgacuuc cgcgaucgcu     1980

uagggaccgu guacgagaag uuuauaaccc cggaagaucu cucgaaauua agcgccgucc     2040

ucgaggauac cgaaaacugg uuguacgagg auggggaaga ucaaccgaag caggucuacg     2100

ucgacaaauu gcaggaguug aaaaaguaug ggcaaccgau ccaaaugaaa uauauggaac     2160

acgaagaacg cccgaaggcg cucaacgauc ucgggaaaaa aauacaauug gugaugaaag     2220

ucaucgaagc cuaccgcaau aaagacgagc gcuacgacca cuuagacccg accgaaaugg     2280

agaaagucga gaagugcaua ucggacgcga ugucgugguu aaacucgaaa augaacgccc     2340

aaaauaaguu gucguugacc caggacccgg ucgucaaggu cagcgagauc gucgccaaaa     2400

gcaaagaguu agacaacuuu ugcaauccga uaaucuauaa accgaaaccg aaggccgagg     2460

ucccggagga uaagccgaag gccaacucgg aacauaacgg gccgauggac gggcaaucgg     2520

ggaccgagac caagagcgac agcaccaagg auucgagcca acacaccaaa aguagcgggg     2580

aaauggaggu cgauugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  5773
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt10)

<400>  5773
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauugaguu uagucgcggc cauguuauua uuauugucgg      120

ccgccagagc ggaagaagaa gauaaaaaag aagaugucgg gaccgucgug gggauagauu      180

uaggcacgac guauaguugu gugggggucu uuaaaaaugg gagggucgaa auaauagcga      240

augaccaagg gaauaggaua acccccaguu acguggcguu uaccccggag ggcgagaggu      300

uaaucgggga cgcggcgaaa aaucaauuga cgaguaaucc ggaaaauacc guguucgaug      360

cgaaaagauu gauagggagg accuggaacg aucccagcgu ccaacaagau auaaaauuuc      420

uccccuuuaa agucgucgag aaaaagacca agccguauau ccaggucgac aucggggggg      480

gccagaccaa aaccuucgcc ccggaggaga ucagcgcgau ggucuugacc aagaugaagg      540

agacggccga agccuaccuc gggaaaaaag ucacgcacgc cgucgucacc gucccggcgu      600

acuucaacga cgcgcagagg caggccacga aggaugccgg gaccaucgcc ggguugaacg      660

ucaugcgcau aauaaaugaa ccgaccgccg ccgccaucgc cuacggguua gacaaacgcg      720

aaggcgaaaa aaauauauua gucuucgauu uagggggggg gacguuugac gucagcuugu      780

ugacgaucga uaacggggug uuugaggucg ucgcgaccaa cggggacacc cacuuagggg      840

gggaggauuu cgaucaaagg gugauggagc auuuuauaaa guuauauaag aaaaaaaccg      900

ggaaggacgu gcgcaaggau aaccgcgccg uccaaaaguu gagaagggaa gucgagaaag      960

cgaagagagc guuaagcagc caacaccagg cccgcaucga gaucgaaagu uuuuacgagg     1020

gggaggauuu cagcgaaacg uuaaccagag cgaaguucga ggaauugaau auggacuuau     1080

uuagaagcac caugaaaccg gugcaaaagg uccucgagga cagcgaccuc aaaaaaagcg     1140

acaucgacga gaucgucuug gucgggggga gcaccaggau cccgaaaauc caacaguuag     1200

ucaaggaauu uuuuaacggg aaagagccga guagggggau caauccggac gaggccgucg     1260

ccuacggggc cgccgugcaa gccggggucu ugagcgggga ccaggacacc ggggauuuag     1320

ucuuauugga cgucugcccg uugaccuugg ggaucgagac cgucgggggg gugaugacga     1380

aguuaauccc gcgcaauacc gucgucccga cgaaaaaaag ccaaauauuc agcaccgcca     1440

gcgacaacca gccgaccguc accauaaaag uguacgaggg ggagcgcccg uuaaccaagg     1500

auaaccacuu guuagggacc uucgacuuaa ccgggauccc gccggccccg aggggcgugc     1560

cgcaaaucga ggugacguuc gaaaucgacg ucaacgggau cuugaggguc accgccgagg     1620

auaaagggac cggcaauaag aacaaaauaa ccauaacgaa cgaucaaaac agguuaaccc     1680

cggaggagau agagcgcaug gucaacgacg ccgaaaaauu cgccgaagag gauaagaaau     1740

ugaaagaaag gaucgacacc cgcaacgaac ucgagucgua cgcguacagc uugaaaaacc     1800

aaaucgggga caaggagaaa uuagggggga aguugaguag cgaggacaaa gaaacgaugg     1860

agaaggccgu cgaggagaaa aucgaguggu uagagucgca ucaggacgcc gauaucgagg     1920

auuuuaaggc caaaaaaaaa gaguuagagg agaucgucca gccgaucaua ucgaaguugu     1980

acgggucggc cgggccgccg ccgaccgggg aggaagacac cgccgagaag gacgaacucu     2040

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  5774
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt10)

<400>  5774
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcgccga gagaauuggc cgucgggaua gauuuaggga      120

cgacguauag cugugucggg gucuuccaac aagggagggu cgaaauauua gcgaaugauc      180

aagggaauag gacgaccccg ucguaugucg cguuuacgga uacggaaaga uuagugggcg      240

augccgcgaa aucgcaagcc gcguuaaauc cgcauaauac ggucuuugac gcgaaaagau      300

uaauaggcag gaaauuugcc gauacgaccg uccaaagcga uaugaaacau uggccguuua      360

gagucgucuc ggaagggggg aaaccgaaag ucagggucug uuauaggggc gaagauaaaa      420

ccuuuuaucc ggaagaaaua agcaguaugg ucuuaucgaa aaugaaagaa accgcggaag      480

ccuauuuagg gcaaccgguc aaacaugccg ucauaacggu cccggcguac uuuaacgaua      540

gccaaaggca agcgacgaaa gaugccggcg cgauagccgg cuugaauguc cucagaauaa      600

uaaacgaacc gaccgccgcc gcgauagcgu acggcuuaga uagaagaggg gccggggaaa      660

ggaaugucuu gaucuucgau uuagggggcg ggacguuuga cgucagcguc uugaguaucg      720

augccggggu guucgaaguc aaggcgaccg ccggggacac gcauuuaggg ggggaagauu      780

uugauaauag auuggucaau cauuuuaugg aggaguuuag aagaaaacac ggcaaagauu      840

uaucgggcaa uaaaagggcg uuaaggcgcu uaaggaccgc gugcgaaagg gcgaaaagga      900

cguuaaguag uucgacgcaa gcgacguuag aaaucgauag uuuauuugaa ggggucgauu      960

uuuauaccag uauaaccagg gcgagguucg aagaguuaug uagcgauuug uuuaggucga     1020

cguuagaacc cgucgaaaaa gcguuaagag acgcgaaauu agauaaagcg caaauccacg     1080

augugguguu agucggcggg aguaccagga uaccgaaagu ccaaaaacuc uuacaagauu     1140

uuuuuaaugg gaaagaauua aauaaaucga uaaauccgga cgaagccguc gcguacggcg     1200

ccgccgucca agccgcgguc cucaugggcg auaagugcga aaagguccaa gacuuguuau     1260

uauuagacgu cgccccgcuc agcuuaggcu uagaaaccgc cgggggcguc augacgaccu     1320

uaauacaacg caaugcgacc auaccgacga aacaaacgca aaccuuuacg acguauagcg     1380

auaaucaacc gggcguguuu auacaagucu acgaagggga acgcgcgaug acgaaagaua     1440

auaauuuauu aggcagguuc gaguugucgg ggauaccgcc ggcgccgagg ggggugccgc     1500

aaaucgaagu caccuucgau aucgacgcca acgggauauu aucggucacc gcgaccgauc     1560

gcucgaccgg gaaagccaau aaaauaacga uaacgaacga uaaagggaga uuaucgaaag     1620

aagaagucga acgcaugguc cacgaggcgg aacaauauaa agccgaagac gaagcgcaac     1680

gcgaucgcgu cgccgcgaag aauagcuuag aagcgcacgu guuucacguc aaggggagcc     1740

uccaggaaga gucguugcgc gauaaaaucc cggaggaaga ucgcaggaag augcaggaua     1800

aaugcagaga gguguuggcg ugguuagaac auaaucaauu agccgaaaaa gaagaauacg     1860

aacaccaaaa acgcgaauua gaacagauau gcaggccgau auuuagucgc uuguacggcg     1920

gcccgggggu gccgggcggg ucgucgugcg ggacccaggc gaggcaaggc gauccgucga     1980

cggggccgau aaucgaagaa gucgacugag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  5775
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt10)

<400>  5775
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggcgcccc gcgagcuggc cgugggcauc gaccucggga      120

ccaccuacag cugcgucggc guguuccagc aggggcgggu ggagauccug gccaacgacc      180

agggcaaccg cacgaccccg uccuacgucg ccuucaccga caccgagcgg cugguggggg      240

acgccgccaa gucgcaggcc gcgcucaacc cccacaacac gguguucgac gccaagcgcu      300

uaaucggccg gaaguucgcc gacaccaccg uccagagcga caugaagcac uggcccuucc      360

aggugguguc ggagggcggg aagcccaagg ucagggugug cuaccggggc gaggacaaga      420

ccuucuaccc ggaggagauc agcagcaugg uguuauccaa gaugaaggag acggccgagg      480

cguaccucgg gcagcccguc aagcacgccg ugaucaccgu gcccaccuac uucucgaaca      540

gccagaggca ggccaccaag gacgccggcg ccaucgcggg gcugaagguc uuacccauca      600

ucaacgaggc cacggccgcc gccaucgcgu acggccucga cagacgcggc gccgggaagc      660

ggaacgugcu gaucuucgac uuaggcgggg gcaccuucga cgugagcguc uugaguaucg      720

acgccggcgu guucgaggug aaggccaccg ccggggacac ccacuuaggc ggggaggacu      780

ucgacaaccg ccuggucaac cacuucaugg aggaguucag acgcaagcac ggcaaggacc      840

ucucggggaa caagcgggcg uuaaggcggu uaaggacggc cugcgagcgg gccaagagga      900

ccccgaguag cuccacccag gccacccucg agaucgacag cuuauucgag ggcguggacu      960

ucuacaagag uaucacgcgg gccagguucg aggaguuaug cagcgacuug uucaggucca     1020

ccuuagagcc cguggagaag gcguuaagag acgccaagcu cgacaaggcc cagauccacg     1080

acuucgucuu aggcgggggc cugcacagcc acccccaggg ggccgaggug gcggccggcc     1140

uccugcagcg ccagggggcc gagcaggagc accagcccug aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  5776
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt10)

<400>  5776
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucgaaggggc cggcgguagg uauagacuua ggcacgacgu      120

acucgugcgu agggguauuc cagcacggca agguagagau caucgcgaac gaccagggga      180

accgaacaac gccgucguac guagcauuca ccgacacgga gcgcuuaaua ggcgacgcgg      240

cgaagaacca gguagcgaug aacccgacua acacggucuu cgacgcgaag cgguuaaucg      300

gucgacgguu cgacgacgcg guaguacagu cggacaugaa gcacuggccc uucauggucg      360

uuaacgacgc agguagaccg aagguacagg uggaguacaa gggcgagacc aagucguucu      420

acccggagga ggucucgucg augguguuaa ccaagaugaa ggagaucgcg gaggcguacu      480

uggguaagac ggugacgaac gcagucguua cggucccggc guacuucaac gacagucagc      540

gacaggcgac uaaggacgcg gguacgaucg cgggauuaaa cgucuuacga aucaucaacg      600

agccgacggc ggccgcgaua gcguacgggc uagacaagaa gguaggugcg gagaggaacg      660

uauuaaucuu cgacuugggg ggcgggacgu ucgacguauc gauauuaacc aucgaggacg      720

guauuuucga gguaaagagu accgcagggg acacccacuu agggggggag gacuucgaca      780

accguauggu aaaccacuuc auagcggagu ucaagcggaa gcacaagaag gacauaucgg      840

agaacaagcg cgccguacga cguuuacgga cggcgugcga gagagcgaag cgaaccuuaa      900

guucgaguac ucaggcaucg auagagauag acucguuaua cgaggggauc gacuucuaca      960

cgucgaucac gcgagcgcgg uucgaggagu ugaacgccga cuuguuccga gggacgcuug     1020

acccggugga gaaggcguua cgggacgcua aguuagacaa gagucagaua cacgacauag     1080

uauuaguagg ggggucgacg cgaaucccua agauacagaa guuauugcag gacuucuuca     1140

acggcaagga guuaaacaag aguauaaacc cggacgaggc aguagccuac ggggcggcgg     1200

uacaggcggc gauucucucg ggugacaagu cggagaacgu gcaggacuua uuauuauuag     1260

acguaacgcc cuuaucgcuc gggaucgaga cggcgggggg gguaaugacg guauugauca     1320

agaggaacac gacgauaccg acgaagcaaa cgcagacguu cacgaccuac ucggacaacc     1380

agccgggcgu auuaauacag guauacgagg gcgagcgggc caugacgaag gacaacaacc     1440

uuuuagguaa guucgaguua acggguauuc cgccggcgcc gaggggggua ccgcaaaucg     1500

agguaacguu cgacauagac gcgaacggga uccuuaacgu aagugcggua gacaagucga     1560

cggguaagga gaacaagauc acgauaacga acgacaaggg ccgcuuaagu aaggaggaca     1620

ucgagcgcau gguacaggag gcggagaagu acaaggcgga ggacgagaag cagcgagaca     1680

agguaucguc gaagaacucg uuggagaguu acgcguucaa caugaaggcg acgguagagg     1740

acgagaaguu acaggguaag aucaacgacg aggacaagca gaagaucuug gacaagugca     1800

acgagauaau caacugguua gacaagaacc agacggcgga gaaggaggag uucgagcacc     1860

agcaaaagga guuagagaag guaugcaacc cgaucauaac gaagcuauac caguccgcgg     1920

gugggaugcc gggggggaug ccgggcgguu uccccggagg gggugccccg ccgagugggg     1980

gggcgucguc gggcccgacg aucgaggagg ucgacugagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  5777
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt10)

<400>  5777
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucucggcgu cgagggccgc cgccgcgagg uuggucgggg      120

cggccgcgag uagagggccg accgcggcga ggcaucaaga cucguggaac ggguugucgc      180

acgaagccuu ccgcuugguc agccgcagag acuacgccag cgaggcgaua aaaggggccg      240

ucgucgggau cgaucucggg accacgaaua guugugucgc cgucauggag gggaagcaag      300

cgaaagucuu agaaaacgcg gagggggcgc gcacgacgcc gagcgucguc gcguucaccg      360

ccgacgggga aagguugguc gggaugcccg cgaaaaggca agccgugacg aauccgaaua      420

auaccuucua cgccacgaaa agguugaucg ggagaaggua cgacgacccg gagguccaaa      480

aggauaucaa gaacgucccg uuuaagaucg ugagggcgag uaacggggac gcgugggucg      540

aagcccaugg caagcucuac agccccucgc aaauaggggc cuucguccuc augaaaauga      600

aggaaaccgc cgagaacuau cucggccaua ccgccaagaa cgccgucaua accgugccgg      660

ccuacuuuaa cgauagccaa cgccaagcga ccaaagacgc cgggcaaauu agcggguuaa      720

acgucuugag agucaucaac gaaccgaccg ccgccgccuu ggcguacggg uuggauaaga      780

gcgaggauaa gguaaucgcc gucuacgacc ucgggggggg gaccuucgac aucagcauau      840

uagagaucca aaaggggguc uucgaaguca agaguaccaa cggcgacacg uuucucgggg      900

gcgaggauuu cgaucaagcg cucuugagac auaucgucaa agaauuuaaa cgcgaaaccg      960

gcgucgaccu caccaaagau aauauggccu ugcaacgcgu cagagaggcc gccgagaaag     1020

ccaagugcga guugaguagc agcguccaaa ccgauauaaa ccucccguac uugaccaugg     1080

acagcagcgg gccgaaacac cucaacauga aacucacgag ggcccaguuc gagggcaucg     1140

ugaccgacuu gauacgccgc accauagccc cgugucaaaa ggccaugcag gacgccgagg     1200

uaucgaaauc ggauaucggg gaggucauau uggucggggg gaugacccgc augccgaaag     1260

uccaacaaac cguccaagau uuguucgggc gcgcgccguc gaaagccgug aacccggacg     1320

aagccgucgc gaucggggcc gcgauccaag gggggguccu cgcgggggac gugaccgacg     1380

ucuuauuguu ggacgugacc ccgcucagcu uagggaucga gaccuugggg gggguguuca     1440

cgaaguugau caaccgcaac acgaccaucc cgacgaaaaa aucgcaaguc uuuagcaccg     1500

cggccgacgg gcagacccag gucgagauca aggucuguca aggggagcgc gaaauggccg     1560

gggauaauaa guuguugggg caauucaccc ucaucgggau cccgccggcg ccgagggggg     1620

ucccgcaaau cgaggucacc uucgauaucg acgcgaacgg caucguccac gucagcgcca     1680

aggacaaggg gaccgggagg gaacaacaaa ucgucauaca aagcagcggg gggcucucga     1740

aggacgacau cgagaacaug gucaaaaacg ccgaaaaaua cgccgaggag gauagaagga     1800

aaaaagagag ggucgaggcg gucaauaugg ccgaggggau aauccaugau accgaaacga     1860

aaauggaaga guuuaaagau cagcucccgg ccgacgaaug uaauaaauua aaggaggaaa     1920

ucaguaagau gcgcgaauug uuagcccgca aagauucgga aaccggggag aacauccgcc     1980

aagccgcgag uagcuugcaa caagccagcu uaaaauuauu ugagauggcc uauaaaaaaa     2040

uggccagcga aagggagggg agcgggucga gcgggaccgg cgagcaaaaa gaggaccaga     2100

aagaagagaa acaaugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  5778
<211>  2375
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt10)

<400>  5778
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagacaagg aagcaggggg uucggacggc ccucgugaga      120

cugcaccuac uucggcguac ucuucgccgg cucgaucguu aggugacacu gggaucacgc      180

cguuaagucc gucgcacaua guaaacgaua cggacaguaa cguaucggag cagcagucgu      240

ucuuaguagu aguagcggug gacuucggua ccacgucguc ggguuacgcg uacucguuca      300

cgaaagagcc ggagugcaua cacgucaugc ggagguggga ggggggagac ccgggcguaa      360

guaaccagaa gacaccuacg acgauauuau uaacgccgga gcggaaguuc cacucguucg      420

guuacgcggc ccgugacuuc uaccacgacu uagacccaaa cgaggcaaag caaugguuau      480

acuuggagaa auucaaaaug aaguuacaca cuacgggaga cuuaacgaug gacacugacu      540

ugacugccgc gaacgguaaa aagguaaagg cgcucgagau cuucgcguac gcauuacagu      600

acuucaagga gcaggccuua aaggagcucu cugaccaggc ugggucagag uucgagaaca      660

gugacguaag guggguaaua acuguaccgg cgauauggaa gcagccagcg aagcaguuca      720

ugcgccaggc agcguaccag gcgggguuag cgucgccgga gaacagugag caguuaauaa      780

ucgcuuuaga accggaagcg gcgucgauau acugccggaa guuacguuua caccaaauga      840

uagaguuauc aaguaaggcg gcgguuaacg gguacucagg uucggacacu guuggggcgg      900

guuucacgca ggcgaaggag cacauccgac gaaacaggca aucgcgcaca uuccucgucg      960

agaacguuau uggcgagauu uggagugagc uugaggaggg agacaaguac guaguaguag     1020

acucgggugg gggaacuguu gauuuaacgg uacaccaaau uaggcuccca gagggucacu     1080

uaaaggagcu cuacaaggcc acgggugguc cguacgguag ucucgggguu gacuacgagu     1140

ucgagaaguu gcucuacaag aucuucggug aggacuucau agagcaguuu aagaucaagc     1200

guccggcggc guggguagac cucaugauag cuuucgaauc gcgaaagcgc gccgcagcgc     1260

cggaccgaac gaacccuuug aacaucacgu uaccguucuc guucauagac uacuacaaga     1320

aguuccgugg acacucggua gagcacgcgu uacgaaagag uaacguagac uucguaaagu     1380

ggucgaguca ggguaugcuu cgcaugucgc ccgacgcgau gaacgcguua uucaagccua     1440

cuaucgacuc gauaauagaa cacuugaggg acuuauucca gaagccggag guaucgacgg     1500

uaaaguucuu auucuuaguc gggggguucg cagaggcgcc guuguuacag caggcaguuc     1560

aggcggcguu cggugaccag ugccgaauaa uaauacccca ggacguaggg uuaacgaucu     1620

ugaagggggc gguuuuauuc ggguuagacc cggccguaau aaagguucga cguucacccu     1680

ugacuuacgg ugucggcguc uuaaaccgau acguagaggg gaagcaccca ccggaaaagu     1740

uguuagucaa ggacggaaca cgauggugca cggacguauu cgacaaguuc auaucggccg     1800

accaaagugu agcguuaggc gaguuaguaa agcgaucgua uacgccugcc aagccgucgc     1860

aauuaguaau agucaucaac aucuacaguu cggagcacga caacguaagu uuuauaacgg     1920

acccgggagu caagaagugc ggaacauuaa gguuagacuu gacggguacg ucggguaccg     1980

cgguuccagc gcgccgagag auacagacgc ucaugcaguu cggugacacg gagauaaagg     2040

cgacggcgau agacaucgcu acgucuaagu cgguaaaggu cgguaucgac uuucucaacu     2100

acugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2160

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2220

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2280

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                2375


<210>  5779
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt10)

<400>  5779
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuagcaguac ccgagauggg auuacaaggu uuauacauag      120

guucgucgcc cgagcguucg ccgguuccgu cgccuccggg gucgccacgc acgcaagagu      180

cgugcgggau agcaccuuua acuccuuccc agaguccuaa gccggaaguu cgugcaccgc      240

agcaggcauc guucaguguc guagucgcua uagacuucgg uacaacaucg ucggguuacg      300

ccuucucguu cgcuucggac ccggaggcaa uccauaugau gcguaagugg gaggguggug      360

acccuggugu cgcgcaccaa aagacgccua cgugcuuauu auuaacgccu gagggggcgu      420

uccacucguu cggauacacg gcgcgagacu acuaccacga cuuggacccc gaggaggcuc      480

gcgacugguu auacuucgaa aaguucaaaa ugaagauaca cucggcgacu gacuuaacgu      540

uaaagacaca acucgaggcg guuaacggga agacaaugcc ggcguuagag gucuucgcgc      600

acgcguugag guucuuccgc gagcacgcgc uccaggaguu acgagagcaa ucgccgucau      660

ugccggagaa agacacgguc cguugggucu uaaccguccc ggcgaucugg aagcaaccgg      720

cgaaacaguu caugcgagag gcggcuuauu uagcgggguu aguaucgcgu gagaacgcgg      780

agcaauuauu aauagcguua gagccggagg cggcgucagu uuacugucga aaguugcgau      840

ugcaccaguu guuagauuua ucaggaaggg cgccgggagg cgggcgauug ggcgagaggc      900

gaucgauaga cucgucguuc cgacaggcgc gcgagcagcu ccgucguucg aggcauucgc      960

ggacguucuu aguagagucg gguguuggug aguuaugggc ggaaaugcag gcgggugacc     1020

guuacguagu cgcugacugc ggugggggga cgguagacuu aacaguucac caguuagagc     1080

agccacacgg uacguugaaa gagcuuuaca aggcgucagg agggccguac ggggccguag     1140

ggguugauuu agcguucgag caguugcucu gccggaucuu cggcgaggac uucaucgcaa     1200

cauucaagcg ccagcgucca gcggcauggg ucgacuuaac aauagcguuc gaggcacgua     1260

agcggacggc aggaccgcau cgagcgggug cauuaaacau aaguuuaccg uucucguuca     1320

uagacuucua ccggaagcaa cgcggucaca acguagagac ggcgcucagg cgaaguucgg     1380

ucaacuucgu aaaguggagu ucgcagggua uguugcgcau gaguugcgag gcgaugaacg     1440

aguuauucca gccaacaguu ucaggcauua uacagcacau ugaggcauua uuggcgcgcc     1500

ccgagguaca gggggucaag cucuuauucu uggucggagg auucgcggag ucggcaguau     1560

uacagcacgc aguacaagcg gcuuuaggug cgaggggcuu acgcguagua guaccccacg     1620

acgucgguuu gacuauauug aagggcgccg uuuuauucgg ucaggcuccg ggagucguca     1680

ggguucgacg gucuccauua acuuacggug ucgguguauu aaaccguuuc guccccggua     1740

ggcacccgcc ggagaaguua uugguacgag acggucgaag guggugcacg gacguguucg     1800

agcguuucgu agcagcggaa cagucagucg cguuaggaga ggagguaagg cguucguacu     1860

guccugcaag gccaggacag cgucgagucu uaauuaacuu guauuguugc gcagcggagg     1920

acgcacgauu cauaacugac ccggguguac ggaagugcgg ugccuuaagu uuggaguuag     1980

aaccggcgga cugcggucag gacacggcgg gugcaccacc gggucgucga gagauccgag     2040

cagcgaugca auucggugau acugagauaa aggugacggc gguagacguu ucgacuaaca     2100

ggucgguccg agcaucgauc gacuucuuau cgaauugagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  5780
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt10)

<400>  5780
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgcgcgaaa ugacuauacu cgggucugcg gucuuaacgu      120

uacucuuagc agguuacuua gcgcagcagu accuuccucu uccgacaccc aagguaauag      180

gaauagacuu agguacgaca uacugcagug ucggaguauu cuucccggga acugguaagg      240

ucaagguaau accggacgag aacggacaca ucucuauccc gucgaugguc ucguucacgg      300

auaacgacgu uuacgucggg uacgagucgg ucgaguuagc ggacucuaac ccgcagaaca      360

cgaucuacga cgcuaagcga uucaucggua agauauucac ggcggaggag uuagaggcag      420

agauagguag guacccguuc aaggucuuga acaagaacgg gaugguagag uucucaguaa      480

ccucgaacga gacgaucacu guaagucccg aguacgucgg uucacguuua cuauuaaagu      540

ugaaggagau ggcggaggcg uacuugggca ugccgguagc gaacgcagua auaucggucc      600

ccgccgaguu cgacuuaaag caacgaaacu cgacgaucga ggcggcgaac uuagcggggc      660

uuaagauccu ucgagugauc aacgagccga cggcggcggc gauggccuac ggguuacaca      720

aggccgacgu auuccacgug cuugucaucg acuuaggagg ugggacacuc gacgucucgc      780

uuuugaacaa gcagggugga auguucuuga cgcgugcgau gucggguaac aacaaguugg      840

gugggcagga cuucaaccag cgauuauuac aguacuugua caagcaaauu uaccagacgu      900

acgguuucgu cccgucacga aaggaagaga uacaucgauu aaggcaggca gucgagaugg      960

uaaaguugaa cuugacguua caccagucgg cgcaauuaag ugucuuguua acgguugagg     1020

agcaggaccg uaaggagccg cacucgucgg acaccgaguu accgaaggac aaguugucgu     1080

cggcugacga ccacagggua aacucggguu ucggcagggg uuuaucagac aagaagucgg     1140

gcgagucgca gguacucuuc gagacggaga ucagucgaaa guuauucgac acguuaaacg     1200

aggacuuauu ccaaaagauc uuaguuccga uccagcaggu uuuaaaggag ggucacuuag     1260

agaagacgga gauagacgag guugucuugg ucggugguuc gacgcgaauc ccccgaauca     1320

ggcagguaau acaggaguuc uucgggaagg acccaaacac gucggucgau ccggacuuag     1380

cgguuguuac cgguguugcg auucaggccg ggauagacgg ggguucgugg ccguuacagg     1440

uaucagcgcu cgagauaccg aacaagcacu ugcagaagac gaacuucaac ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  5781
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt10)

<400>  5781
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgcgauag ggguccauuu aggguguacg agcgcgugcg      120

ucgcggugua caaagacggg agagccgggg ucgucgccaa cgacgcgggg gauaggguca      180

ccccggccgu cgucgccuau agcgagaacg aggaaaucgu cgggcucgcc gccaagcagu      240

cgcgcauccg caacaucagc aauaccguca ugaaggucaa acaaauauua gggcgcucga      300

guucggaucc gcaggcgcaa aaguauauag ccgagucgaa gugccucgug aucgaaaaga      360

acggcaagcu cagguacgag aucgacaccg gggaggagac caaguucguc aauccggagg      420

acgucgcgcg cuuaauuuuu ucgaaaauga aggagaccgc ccacagcguc cucgggagcg      480

acgccaacga cgucgucauc accgugcccu ucgacuucgg ggaaaaacag aagaacgccu      540

ugggggaggc cgcccgcgcc gccggguuca acguccucag gcucauccau gaacccagcg      600

ccgccuuguu ggccuacggg aucgggcagg auaguccgac cgggaagucg aacauccucg      660

ucuuuaaauu gggggggacc agucucagcu ugucggugau ggaggucaau ucggggaucu      720

acagagucuu gagcacgaau accgacgaca auauaggggg ggcccauuuu accgagacgc      780

ucgcccaaua cuuggccagc gaauuucagc gcaguuuuaa gcacgacguc cgcgggaacg      840

ccagggcgau gaugaagcuc accaauucgg ccgaggucgc caaacacagc cucagcacgc      900

ucgggucggc gaauugcuuu uuggauagcc ucuacgaggg gcaggacuuc gacuguaacg      960

ucagucgcgc ccgcuucgag uuguugugca gcccguuguu caacaaaugc aucgaggcca     1020

uacgcggguu gcucgaccag aacggguuua ccgccgacga cauaaauaaa gucguguugu     1080

gcgggggcag cagcaggaua ccgaaauugc aacaauuaau caaggacuug uuuccggccg     1140

ucgaauuguu gaacagcaua ccgccggacg aggucauacc gaucggggcc gccaucgagg     1200

ccgggaucuu gaucggcaag gagaauuuac ucgucgaaga uagcuugaug aucgaaugca     1260

gcgcgcgcga cauccucguc aaaggggucg augagagcgg ggcgucgcgc uuuaccgucu     1320

uauucccgag cggcaccccg cucccggcca ggcgccagca uacccuccaa gcgccggggu     1380

cgaucagcag cgucuguuug gaguuguacg aaagcgacgg caaaaauagc gcgaaagaag     1440

agacgaaauu cgcccaaguc gucuugcaag aucucgauaa gaaggagaac gggcucaggg     1500

acauccucgc cgucuugacc augaagcgcg acgggagccu ccacgucacc uguaccgacc     1560

aagaaaccgg gaagugcgag gccauaagca ucgaaaucgc cagcugagga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  5782
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt10)

<400>  5782
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgugguag gacucgacgu cgggagccaa agcugcuaca      120

uagcgguagc cagggcaggc gggauagaga cgaucgccaa cgaguucucc gaucgcugca      180

cacccagcgu caucagcuuu gguucuaaaa acaggacuau aggaguggcc gcgaaaaacc      240

aacaaauaac ccaugcaaac aacaccguca gcaacuucaa acgauuccac ggacgugccu      300

ucaacgaccc guuuauacaa aaagaaaaag aaaaccuauc cuacgaccua gucccccuca      360

agaauggagg cgugggcauc aaaguuaugu auaugggaga agaacacuug uucucaguag      420

aacagauaac cgccaugcua cuaacaaaac ugaaggaaac cgcagagaac agucugaaga      480

aaccugucac cgacugcgua aucuccguac ccuccuucuu caccgacgca gaacggagau      540

ccguacuaga cgcagcccaa auaguaggcc uaaacugccu ccgcuugaug aacgauauga      600

cggccguagc acucaacuau gggauuuaca aacaagaccu cccaagccuc gacgaaaaac      660

cccgcauagu agucuucguc gacaugggac acucagcauu ccagguaagc gcaugcgccu      720

ucaacaaagg aaaacucaaa gucuuaggca cggcuuucga ccccuuccua ggcgggaaaa      780

auuucgacga gaaacucguc gaacacuucu gcgccgaguu caaaaccaaa uacaaacucg      840

acgcaaagag caaaauccga gcccuccuac gcuuauacca ggaaugcgaa aagcuaaaga      900

aauugauguc cuccaacucc accgaccuac ccuuaaacau cgaauguuuc augaacgaca      960

aggacgucag cggaaagaug aacagauccc aguucgagga gcucugcgcc gaguuauuac     1020

aaaagauaga agucccccuc uacagccuuc ucgaacagac ccaccucaaa guagaagacg     1080

uuucagccgu cgaaaucguc ggcggagcaa cacgcauccc cgcggucaaa gaacgcaucg     1140

ccaaauucuu cgggaaggac auauccacca cccuaaacgc agacgaagca guggcacgcg     1200

ggugugcccu ccagugcgcc aucuuaagcc ccgcauucaa aguacgagag uucucaguaa     1260

ccgaugccgu cccguuccca auaagccuga uauggaacca cgacagcgag gacaccgaag     1320

guguccacga agucuucagu cgaaaccacg cggccccauu cucaaaagua uuaacguucc     1380

uccgacgcgg acccuucgaa cucgaagcau ucuacagcga cccgcaaggc guaccguacc     1440

cugaggcaaa gauuggcagg uucguagucc agaacgucuc cgcacaaaaa gauggcgaga     1500

aaagccgcgu aaaggucaaa guccgaguca auacacacgg aaucuucacc auuuccaccg     1560

ccucaauggu agaaaaaguc cccacagaag aaaacgagau gagcucugaa gccgacaugg     1620

agugccucaa ccaacgccca cccgaaaacc ccgacaccga caagaacguc caacaagaca     1680

acagcgaagc aggaacccag ccccaagucc aaaccgacgc acaacagacc agccagagcc     1740

cacccucccc cgagcucaca ucagaagaaa auaagauccc agacgcagac aaggccaacg     1800

aaaagaaagu cgaccagccc ccggaggcca agaaacccaa aaucaaagug gucaacguag     1860

aacuccccau cgaagcaaac cuggucuggc agcuagguaa agacuuauua aacauguaca     1920

ucgaaaccga aggcaaaaug auaaugcaag auaaacucga aaaagaacgc aacgacgcca     1980

aaaacgcagu cgaagaauac guauacgagu uccgggacaa auuaugcggc ccauacgaaa     2040

aauucaucug ugaacaagac caccaaaacu uucuacguuu auuaaccgaa accgaagacu     2100

ggcucuacga agaaggcgaa gaucaagcaa aacaggcuua cgucgauaaa cucgaagaac     2160

uaaugaaaau cggaacgccg gucaaagugc gguuccaaga agcagaagaa cgucccaaaa     2220

uguucgagga acucggacaa agacuccaac acuacgcgaa aaucgccgcc gacuuccgca     2280

acaaagacga gaaguacaac cacaucgacg aaucagaaau gaagaaagua gaaaagucgg     2340

ucaacgaagu aauggaaugg augaacaacg uaaugaacgc ccaagccaaa aagucccucg     2400

accaagaccc agucguccga gcacaagaaa ucaaaaccaa aauuaaggaa cucaacaaua     2460

ccugcgagcc cgucguaacg caaccgaaac caaaaauaga aucccccaaa cucgaacgaa     2520

cccccaacgg gccgaacauc gacaagaaag aagaagaccu cgaggacaaa aacaacuucg     2580

gagcagaacc accacaccaa aacggcgaau gcuacccaaa cgagaaaaac agcgucaaca     2640

uggaccucga uugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  5783
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt10)

<400>  5783
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgauaagg uccgccgcca acgcccccgc cgcagggugu      120

gcugggcgcu cgucgccguc uugcucgccg auuuacucgc cuuaucggac accuuagccg      180

ucaugagcgu cgauuuaggg ucggaaagua ugaaagucgc gaucgugaag ccgggggucc      240

cgauggagau cgugcucaac aaagagagca gacgcaagac ccccgucaua gucacguuaa      300

aggagaacga gcgcuuuuuc ggggauucgg ccgccucgau ggccaucaaa aacccgaaag      360

ccaccuugag guauuuucaa cauuuguuag gcaaacaagc cgacaauccg cacgucgccu      420

uguaucaagc gagguuuccc gaacaugaau uaaccuuuga uccgcaacgc caaaccgucc      480

auuuccaaau aucgagccaa uuacaauuua gcccggaaga gguccucggg auggucuuga      540

acuacagcag gagcuuggcc gaggacuucg ccgaacaacc gauaaaagac gccgucauaa      600

cggucccggu guuuuuuaau caagcggaaa ggagggccgu cuuacaagcc gccaggaugg      660

ccggguugaa ggucuuacaa uugauaaacg auaauacggc gaccgcguug ucguacgggg      720

uguuuaggag aaaggacauc aauacgaccg cgcaaaacau aauguuuuac gauaugggga      780

gcgggucgac ggucuguacg aucgucacgu aucaaauggu caaaaccaaa gaggccggca      840

ugcaaccgca auuacaaaua agaggggucg gguucgauag gacguuaggc ggguuagaaa      900

uggaauugag auugagggag agguuagccg gcuuguuuaa cgaacaaagg aaagggcaac      960

gcgccaaaga cgucagagaa aaucccaggg cgauggcgaa auuauuaagg gaagccaaca     1020

gauugaagac gguguugucg gcgaaugccg aucauauggc ccaaaucgag ggguuaaugg     1080

acgacgucga uuuuaaagcc aaggucacca gggucgaguu cgaagaacuc ugcgccgauc     1140

ucuucgaaag agucccgggc ccgguccaac aagcguugca aucggcggag augucguuag     1200

acgaaaucga acaagucaua uuagucgggg gcgcgaccag agugccgcgc guccaagaag     1260

ucuuauuaaa agcggucggg aaagaagaau uaggcaaaaa uauaaacgcc gacgaggccg     1320

cggcgauggg cgccgucuau caagccgccg ccuugucgaa ggcguucaag gucaaaccgu     1380

ucguggugag ggacgccguc guguauccga uauuagucga auuuacccgc gaagucgaag     1440

aagaaccggg cauccauucg uuaaaacaua acaagagagu cuuguuuagc agaaugggcc     1500

cguauccgca gaggaaggug auaacguuca auagguauuc gcacgacuuu aauuuucaua     1560

uaaauuaugg ggauuuaggg uuuuuaggcc cggaggacuu gagagucuuc gggagucaaa     1620

acuuaacgac cgucaaauug aagggcgucg gggauucguu uaaaaaauac ccggauuaug     1680

aaaguaaagg gauaaaagcc cauuuuaauu uagacgaauc gggggucuug ucguuggauc     1740

gcgucgaaag cgucuucgaa accuuagucg aagauucggc cgaggaagag agcaccuuga     1800

cgaaguuggg gaauacgauc aguucguuau ucgggggggg gacgaccccg gacgcgaaag     1860

aaaacgggac cgacaccgug caagaagagg aagaaucgcc ggccgaaggc ucgaaagaug     1920

aaccgggcga acaagucgaa uugaaagaag aggccgaagc gccggucgaa gacgggagcc     1980

aaccgccgcc gccggagccg aaaggggacg ccacgccgga aggggagaaa gcgaccgaga     2040

aggagaacgg cgauaaaagc gaagcgcaaa agccgucgga aaaagccgaa gccggcccgg     2100

aagggguggc cccggcgccg gaaggggaaa aaaaacaaaa accggcgcgc aaaagaagga     2160

uggucgaaga aauaggcguc gaauuagucg ucuuagauuu accggaucuc ccggaagaca     2220

aauuagccca aagcguccaa aaguugcaag aucucaccuu gagggauuua gaaaaacaag     2280

agagagagaa ggccgcaaau ucgcucgagg ccuuuaucuu cgaaacgcaa gauaaauuau     2340

aucaaccgga auaucaagag gucaguaccg aagaacaaag ggaagaaaua agcggcaaau     2400

ugucggcggc caguacgugg uuagaagacg aaggggucgg ggcgacgacc gucaugcuca     2460

aagaaaaauu agccgaauua cgcaaauuau gucagggcuu auucuucaga gucgaagaaa     2520

ggaaaaaaug gccggagaga uuaagcgcgu uggacaacuu guugaaucac aguucgaugu     2580

uuuugaaagg cgcgagauug auaccggaaa uggaucaaau auuuaccgaa gucgaaauga     2640

ccacccucga aaaggugaua aacgaaacgu gggcguggaa aaacgccacc uuagcggaac     2700

aagccaaauu accggcgacc gaaaaaccgg uccucuugag caaggauauc gaggccaaaa     2760

ugauggcguu agauagggaa guccaauacu uauugaacaa agcgaaauuc acgaaaccga     2820

gaccgagacc gaaagauaaa aacggcacga gagccgaacc gccguugaac gcgucggcgu     2880

cggaucaagg cgaaaaagug auaccgccgg ccgggcaaac cgaggacgcc gaaccgauca     2940

gcgagccgga aaaggucgaa accgggagug aaccggggga uaccgaaccg cucgaacucg     3000

gggggccggg ggccgagccg gagcaaaagg agcagagcac cgggcaaaaa agaccgcuca     3060

aaaaugauga guugugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  5784
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt10)

<400>  5784
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggaggaga cgcaaacgca ggaucagccg auggaggaag      120

aggagguaga gacauucgca uuccaggcgg agauagcaca auuaaugucg uuaauaauua      180

acacguucua caguaacaag gagauauucu uaagggaguu aauaucgaac ucgucggacg      240

cguuggacaa aauacgauac gaaucguuaa cggacccguc gaaguuagac ucggguaagg      300

aguugcacau caacuuaauu ccgaacaagc aggaccggac guuaacgaua guagacacgg      360

guauaggaau gacgaaagcg gacuugauaa acaacuuagg aacgauagcg aagucgggua      420

cuaaggcguu cauggaggca uuacaggcgg gugcggacau aaguaugaua ggucaauucg      480

gggucggauu cuacucggca uacuuagucg cagagaaggu aacgguaauc acgaagcaca      540

acgacgacga acaauacgcc ugggagaguu cggcgggugg uaguuucacg guacgcacug      600

acacggguga gccgaugggu agggguacga agguaauauu acacuuaaag gaggaccaga      660

cggaauacuu agaggagcgc cggaucaagg agauuguuaa aaagcacucg caauucaucg      720

gcuacccuau aacguuauuc gucgagaagg agcgcgacaa ggagguuagu gacgacgagg      780

cggaggagaa agaggacaag gaggaggaga aggaaaagga ggagaaggag ucggaggaca      840

agccggagau agaggacgua ggaucggacg aggaggagga gaagaaggac ggggacaaaa      900

agaagaagaa aaagauaaag gagaaauaca uagaccaaga ggaguuaaac aagacgaagc      960

cgaucuggac aaggaacccg gacgacauaa cgaacgagga guacggugag uucuacaagu     1020

cguuaacaaa cgacugggag gaccacuuag cggucaaaca cuucagugua gaggggcagu     1080

uagaguuccg cgcguuguua uucguaccga ggcgcgcgcc guucgacuua uucgagaacc     1140

ggaagaagaa aaacaauaua aaguuauacg uccgaagggu auucauaaug gacaacugcg     1200

aggaguuaau uccggaguac cucaacuuca uacgcggugu cgucgacucg gaagacuugc     1260

cguuaaacau cucgcgagag auguuacagc agucgaagau cuuaaaggua auacgcaaga     1320

acuuagucaa gaagugcuua gaguuauuca cggaguuggc agaggacaag gagaauuaca     1380

aaaaauucua cgagcaguuc ucgaagaaua uaaaguuagg gauacacgag gacagucaga     1440

accgaaaaaa guuaucagaa uuauuacgau acuauacgag ugcgucgggg gacgaaaugg     1500

ucaguuugaa ggacuauugu acacggauga aggaaaacca aaagcacaua uacuacauaa     1560

cgggggagac gaaggaccaa guugcgaacu cggcauucgu cgagcgcuua cggaagcacg     1620

gguuagaggu cauauacaug aucgaaccua uagacgagua uugcguacag caauugaagg     1680

aguucgaggg gaagacauua guaaguguaa caaaggaggg guuagaguug ccggaggacg     1740

aggaggagaa gaagaagcag gaggagaaga agacgaaguu cgagaacuua ugcaagauaa     1800

ugaaggacau auuagagaag aaggucgaga aggucgucgu cucuaacagg uugguaacgu     1860

cgccgugcug cauaguaacg ucgacuuacg guuggacugc gaacauggaa cgaauaauga     1920

aggcgcaggc guuaagggac aacaguacga uggguuacau ggcggcaaag aagcauuuag     1980

aaaucaaccc ggaccacucg aucauagaga cguuacgaca gaaggcggag gcggacaaga     2040

acgacaagag ugucaaagac uuaguaauau uauuauacga gacggcguug uuaucgagug     2100

gguucucguu agaggaccca caaacucacg cgaaccgaau auaucgcaug auaaaguugg     2160

gauuaggaau cgacgaggac gacccgacgg cggacgacac aucggcggcc guaaccgagg     2220

agaugccgcc guuagagggu gacgacgaua cuucgcggau ggaggaggua gacugaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  5785
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt10)

<400>  5785
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggaggagg uccaucaugg cgaggaagag guggagacgu      120

uugcguuuca agcggaaauc gcgcaguuga ugucgcucau aaucaauacg uuuuauagua      180

auaaggagau auuuuugcgc gaacucauca gcaaugccuc ggaugcguua gauaaaaucc      240

gcuaugaguc guugaccgau ccgagcaagu uagauagcgg gaaagaacuc aagaucgaua      300

uaauaccgaa uccgcaggag aggaccuuga cguuggucga uacggggauc gggaugacca      360

aggcggauuu gaucaauaac uuggggacca ucgcgaaauc gggcaccaag gcguuuaugg      420

aagcguugca ggccggggcg gauaucucga ugauagggca guuugggguc ggguuuuauu      480

cggccuauuu gguggcggag aaagucgucg ucauaaccaa gcauaaugau gaugagcagu      540

augcguggga gucgucggcg gggggcucgu uuaccgugcg cgccgaucau ggggagccga      600

ucgggagggg caccaagguc auauugcauu ugaaagagga ucagacggag uaucucgagg      660

aaaggcgcgu gaaagaggug gugaagaagc auucgcaauu uauaggguau ccgaucacgu      720

uguauuuaga gaaggaacgc gagaaagaga ucucggauga ugaagcggaa gaggagaagg      780

gggagaagga ggaggaggau aaggaugaug aggagaaacc gaaaauagag gaugucgggu      840

cggaugagga ggaugauagc gggaaagaua aaaagaagaa gaccaagaag auaaaggaaa      900

aguauauaga ucaggaggaa uuaaauaaga ccaagccgau auggacgcgc aauccggacg      960

auauaaccca ggaggaguau ggcgaguuuu auaagagcuu gaccaaugau ugggaagauc     1020

auuuggccgu caaacauuuu ucggucgagg ggcaguugga guuucgcgcc uuguuguuua     1080

uaccgcgccg cgccccguuu gauuuauuug agaauaaaaa gaagaagaau aauaucaaau     1140

uguaugugag gaggguguuu aucauggaua gcugugauga guuaauaccg gaguauuuga     1200

auuuuauaag aggggucguc gauagugagg auuugccguu gaauauaucg agggagaugu     1260

ugcagcaauc gaaaaucuua aaggucauac gcaagaauau agucaagaaa uguuuggagu     1320

uguuuucgga gcucgccgaa gacaaggaga auuauaaaaa guuuuaugag gcguuuucga     1380

aaaauuugaa guuagggauc caugaggauu cgacgaacag gcgcagguug ucggaguugu     1440

ugcgcuauca uaccucgcaa ucgggggaug aaaugaccuc guugagugag uaugucucga     1500

gaaugaagga gacccagaaa agcaucuauu auauaacggg ggaaucgaaa gagcaggucg     1560

ccaauagcgc cuuuguggag agggucagga aaaggggguu ugaggugguc uauaugaccg     1620

aaccgauaga ugaauauugc guccagcaau ugaaggaguu ugaugggaag ucguugguga     1680

gcgucacgaa ggagggguug gagcucccgg aggaugagga ggaaaaaaag aagauggagg     1740

agagcaaggc gaaguuugaa aaucucugua aauuaaugaa ggaaauauug gauaagaaag     1800

ucgagaaagu gaccauaagc aauagauuag ucucgagccc guguuguaua gugaccucga     1860

ccuaugggug gaccgccaau auggagagga ucaugaaggc ccaggcguug cgcgauaaua     1920

gcacgauggg cuauaugaug gcgaaaaagc auuuggagau caauccggau cauccgaucg     1980

ucgagaccuu gcgccagaaa gcggaggccg auaagaauga uaaggcgguc aaggauuugg     2040

ucguguuauu guuugagacc gcguuguuga gcucgggguu cagcuuagaa gauccgcaga     2100

cgcauucgaa ucgcauauau aggaugauca aauugggguu agggaucgau gaagaugagg     2160

ucgcggccga ggaaccgaau gccgccgugc cggaugagau acccccguua gagggcgaug     2220

aagaugccag ccgcauggag gaaguggauu gaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  5786
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt10)

<400>  5786
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcgcguugu gggucuuggg uuuguguugu gucuuguuga      120

cauuugggag cgugagggcc gaugaugaag uggauguaga ugggaccgug gaggaagauu      180

uggggaaguc gagggagggg ucgagaaccg acgaugaagu gguacaaagg gaagaggaag      240

ccauccaauu ggacggguug aaugcgucgc aaaucaggga auugagagaa aaaucggaga      300

aauucgcguu ucaggcggag gugaaucgca ugaugaaguu gauuauaaau aguuuguaua      360

agaacaagga aaucuuuuua agagaguuga uaaguaaugc gucggacgcg cucgacaaaa      420

ucagguugau aucguuaacc gaugagaacg cgcucucggg caaugaagag uugacgguca      480

agaucaaaug ugauaaagaa aaaaauuuau ugcacgucac cgauacaggg gucgggauga      540

cgagggagga auuggugaag aauuugggga cgaucgcgaa aucggggacc ucggaauuuu      600

ugaauaagau gaccgaagcg caagaggaug ggcaaagcac cucggaauug aucgggcaau      660

uuggcgucgg cuuuuauucg gccuuuuugg ucgccgauaa agucaucgug accucgaagc      720

auaauaauga cacgcaacau auuugggaaa gcgauucgaa ugaguucucg gucauagccg      780

aucccagagg gaauaccuug gggcgcggga cgacgauaac cuuggucuug aaagaggaag      840

ccagcgauua uuuggaguua gauaccauaa agaauuuggu caaaaaguac ucgcaauuua      900

uuaauuuucc caucuaugug uggucgagca aaaccgagac cgucgaagaa ccuauggaag      960

aagaagaagc cgcgaaggag gaaaaggagg agagcgacga ugaggccgcc guggaagagg     1020

aggaagagga aaagaaaccg aaaacgaaaa aggucgaaaa gacggucugg gauugggagu     1080

ugaugaacga uauuaagccg aucuggcaaa ggcccucgaa ggagguggaa gaggaugaau     1140

auaaggcguu uuauaaaucg uuuucgaaag agucggacga uccuauggcg uacauccauu     1200

ucaccgcgga gggggaaguc accuuuaagu cgauauuguu ugugccuacc ucggcgccgc     1260

gcggguuguu cgaugaguau ggcucgaaaa aaucggauua uauaaaguug uauguaagga     1320

gagucuuuau uacggaugau uuucaugaua ugaugccgaa auauuuaaau uucgugaaag     1380

gggucgucga cagcgacgau uuaccguuga acgucucgcg cgaaaccuug caacaacaua     1440

aguuauugaa agucaucagg aaaaaauugg ugcgcaagac cuuggauaug auaaaaaaaa     1500

ucgccgacga caaauauaac gauaccuuuu ggaaggaauu ugggacaaau auuaaguugg     1560

gggucauaga ggaucauucg aacaggaccc gcuuggccaa guuguugcgc uuucaaucgu     1620

cgcaccaucc gaccgauauc accucguuag aucaauacgu cgagaggaug aaagagaagc     1680

aagauaagau auauuuuaug gccgggaguu cgaggaagga agccgagucg ucgccguucg     1740

ucgaaagguu guugaaaaaa ggguacgagg ugauauaucu cacggagccg gucgaugagu     1800

auuguauaca agcguugccg gaauuugaug ggaaacgcuu ucaaaacgug gccaaagagg     1860

gggucaaauu ugaugagucg gaaaaaacca aagaaagccg cgaggccgug gaaaaggaau     1920

uugaaccguu auugaauugg augaaggaua aggcauugaa agauaaaauc gagaaagccg     1980

ucgucagcca aagauuaacg gaaucgccgu gcgcguuggu ggcaucgcaa uauggguggu     2040

cggguaauau ggaacgcaua augaaagccc aagcguauca aaccgggaaa gauauaucga     2100

cgaauuauua ugcgucgcaa aaaaaaaccu uugagauaaa uccgcgccau cccuugauuc     2160

gcgauauguu gaggcgcaua aaagaggaug aagacgauaa aacggucuug gauuuggcag     2220

uagucuuguu ugagaccgcg accuugcgcu cgggguauuu auugccggau accaaggcgu     2280

auggggauag gauagagagg auguugcgcu ugucguugaa uaucgauccg gacgccaaag     2340

ucgaggaaga accggaagaa gaaccggagg aaaccgccga agauacgacg gaagauaccg     2400

aacaagauga agacgaagaa auggacguag ggaccgauga ggaagaggag acggccaaag     2460

agagcacggc cgagaaagau gaguugugag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  5787
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt10)

<400>  5787
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgagggagc ucagggcguu guuguugugg gggaggaggu      120

ugaggccguu guugagggcg ccggccuugg cggccgugcc gggggggaag ccgaucuugu      180

guccgaggcg caccaccgcc caguuggggc cgaggaggaa uccggcgugg agcuugcaag      240

cggggagguu guuuaguacc cagacggcgg aggauaagga ggagccguug cauucgauca      300

uaucgucgac ggaaaguguc caggggucga cgaguaagca ugaauuucaa gcggagacga      360

aaaaguuguu ggauauaguc gcgaggucgu uguauaguga gaaggaggug uuuauaaggg      420

aguugauaag caaugccagu gaugccuugg agaaguugag gcauaaguug gucagcgaug      480

ggcaggccuu gccggagaug gagauccacu ugcagacgaa ugccgagaag gggacgauca      540

ccauccagga uaccgggauc gggaugaccc aagaagaguu ggugagcaau uuggggacca      600

ucgcgagguc ggggucgaag gcguuuuugg augcguugca gaaucaggcg gaggcgagua      660

guaagauaau agggcaauuu ggggucgggu uuuacagugc guuuaugguc gccgauaggg      720

uggaggucua cagcaggagc gccgcgccgg ggaguuuggg guaucagugg uugagugaug      780

ggucgggggu cuuugagauc gccgaggcga gcggggugag gaccgggacg aagauaauaa      840

uccauuugaa gucggauugu aaggaguucu cgagcgaggc gagggugagg gaugugguga      900

cgaaguacag caacuuugug agcuucccgu uguacuugaa ugggcgcagg augaauaccu      960

ugcaggcgau auggaugaug gauccgaagg augugaggga guggcaacac gaggaauuuu     1020

auagguaugu cgcccaggcc caugauaagc cgagguauac guugcauuau aagaccgaug     1080

cgccguugaa uauaaggagu auauuuuaug uccccgauau gaagccgucg auguuugaug     1140

ucaguaggga guuggggagc agcgucgccu uguauagccg caagguguug auccagacca     1200

aggcgacgga uauauugccg aagugguuga gguuuauacg cgggguggug gauucggagg     1260

auauaccguu gaauuugagc agggaguugu ugcaggagag ugcgcucaua aggaaguuga     1320

gggaugucuu gcagcaaagg uugaucaagu uuuuuauaga ccagaguaaa aaggacgccg     1380

agaaguaugc gaaguuuuuu gaggauuaug gguuguuuau gagagagggg auagucaccg     1440

ccacggaaca ggaagugaag gaagauaucg ccaaguuguu gcgcuaugaa aguucggcgu     1500

ugccgagcgg gcaguugacc ucguugucgg aguaugcgag caggaugcgc gccgggacga     1560

ggaauauaua uuauuugugu gcgccgaaua ggcauuuggc cgagcauagc ccguauuaug     1620

aagcgaugaa gaaaaaggau acggaggugu uauuuuguuu cgagcaguuu gaugaguuaa     1680

cguuguugca uuugcgcgaa uuugauaaga aaaaguugau aucgguggaa accgauauag     1740

uggucgauca uuauaaggag gagaaguuug aagauagguc gccggcggcc gaguguuuga     1800

gcgagaagga gacggaggag uugauggcgu ggaugagaaa uguguugggg agucgcguca     1860

cgaaugucaa ggugaccuug cgcuuggaua cgcauccggc gauggugacg gucuuggaga     1920

ugggggccgc gaggcauuuu uugaggaugc agcaguuggc caagacccaa gaagagaggg     1980

cgcaguuguu gcagccgacg uuggagauca auccgaggca ugcguugauc aaaaaguuga     2040

accaguuacg cgcgagugaa ccgggguugg cgcaguuguu gguggaucaa auauaugaga     2100

augcgaugau agccgccggg uuggucgaug auccgagggc gauggucggg agguugaacg     2160

aguuguuggu gaaggccuug gaaaggcacu gaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  5788
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt10)

<400>  5788
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gguaagaucu cgucauuacc gacgcaguug uucaagugcu      120

gcuucugcga cuucuuaaag guaaagaugc acacgauguc gaguucccac uuauucuacu      180

uggccuuaug cuuguugacg uucaccuccu cggcgaccgc agggccggag accuugugcg      240

gcgcggaguu aguagacgcg uuacaguucg ucugcgguga ccgagguuuc uacuucaaca      300

agccgacggg uuacgggucc ucgucgcgcc gugcaccgca gacgggcauc guugacgaau      360

gcugcuuccg uucuugcgac cuccgucgcu uagagaugua cugcgcgccg uugaagccgg      420

cgaagucggc ccguucggua cgcgcgcagc ggcacacgga caugccaaag acgcagaaag      480

agguccacuu aaagaacgcg ucgcguggau cggccggcaa caagaacuac cggaugugag      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  5789
<211>  890
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt10)

<400>  5789
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcauaccca uggguaaguc aauguuggug uuauuaaccu      120

ucuuagccuu cgccucgugc ugcaucgcgg ccuaccgucc gucagagacc cuaugcggcg      180

gggagcuagu agacacgcua caguucgugu gcggcgaccg gggguucuac uucucgcgcc      240

ccgcgucgcg cgugucccgc cguucgcgcg gcaucguaga ggagugcugc uuccgaucau      300

gcgacuuggc cuuauuagag accuacugcg ccaccccggc caagucggag cgagacgugu      360

cgacgccgcc gaccguguua ccggacaacu ucccccggua ccccgucggc aaguucuucc      420

aguacgacac guggaagcag ucgacucaga gacuucgucg cggguuaccg gcguuguugc      480

gugcccgacg aggccacgug cuagccaagg aguuagaggc guuccgcgag gcgaagcggc      540

accgcccguu aaucgcguua cccacucagg accccgcgca cggaggcgcc ccgcccgaga      600

uggcgucgaa ccgaaaguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      660

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      720

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      780

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 890


<210>  5790
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt10)

<400>  5790
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacucguuca guacgucggc guucggcccc gucgcguucu      120

cguuagguuu guuauugguc uuaccggcgg cguucccagc gcccguucca ccgggugagg      180

acucgaagga cguugcggcg ccccaccgac agcccuugac cucguccgag cguaucgaca      240

agcagauccg auacaucuua gacgguauaa gugcguuacg caaggagacg ugcaacaaau      300

cgaacaugug cgagaguucg aaggaggcgu uagccgagaa caaccucaac uugccgaaga      360

uggcggagaa ggacgggugc uuccagagug gguucaacga ggagacaugc uuaguaaaga      420

ucauaacggg ccuccuugag uucgaggucu accucgagua cuuacagaac agguucgagu      480

caucggagga gcaggcacgc gcgguucaaa ugucgacgaa gguauugauc caguuccucc      540

agaagaaggc caagaacuua gacgcgauca cgacgccgga cccgacuacc aacgcgaguu      600

uguuaacuaa guuacaggcg cagaaccagu gguugcagga caugaccacc cacuugaucu      660

ugcggucguu caaggaguuc uugcagaguu cuuuaagagc guuaaggcag augugaggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  5791
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt10)

<400>  5791
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccguuauugu gguuaagggg guucuuguua gcgucgugcu      120

ggaucaucgu gcguucgucg ccgacgcccg ggucggaggg ucacucggcc gcaccggacu      180

gcccaaguug cgcacuugcc gcguuaccga aggacguucc gaacucgcag ccggagaugg      240

uugaggccgu gaaaaagcac auauugaaca uguuacaccu aaagaagcga ccggacguaa      300

cgcagccggu ccccaaagcg gcccuauuaa acgcuauacg gaaguuacac guugggaagg      360

uaggcgagaa cgguuacgug gagaucgagg acgacaucgg gcgccgcgcc gagaugaacg      420

aguuaaugga gcagacguca gagaucauca ccuucgcgga gucgggcacu gcgcguaaga      480

cuuugcacuu cgagaucucg aaggaggguu cggacuuauc ggugguagag cgggccgagg      540

ugugguuauu cuugaaggug ccgaaggcga accgaacgcg aaccaagguc accauccgau      600

uguuccagca acagaaacac ccccagggga guuuagacac cggggaggag gccgaggagg      660

uaggucucaa gggggagcga uccgagcucc ucuuaucgga gaaggugguc gacgcgcgaa      720

agucuacgug gcacguauuc ccggugucgu cgucgaucca gcgccuacuu gaccagggca      780

agaguucguu ggacguccgc auagcgugcg agcagugcca ggagucgggc gcgucucuug      840

uauuguuagg gaagaagaag aagaaggagg aggaggguga ggggaagaag aaggggggcg      900

gggagggcgg ggcgggcgcg gacgaggaga aggagcaguc ucaccggccg uucuuaaugu      960

uacaagcgcg ucaaucggag gaccacccgc accgacgacg ccgacguggg uuagagugcg     1020

acggcaaggu gaacaucugc ugcaagaagc aguucuucgu uucauucaag gacaucgguu     1080

ggaacgacug gauaauagcc ccgucggggu accacgcgaa cuacugcgag ggcgagugcc     1140

cgucccacau cgccgguacu ucgggcucgu cguuaucguu ccacaguacg guuauaaacc     1200

auuaccguau gcguggacac ucccccuucg cgaacuugaa gaguugcugc gugccgacca     1260

aguugcgucc caugucgaug cuuuacuacg acgacggcca gaacauuaua aagaaggaca     1320

uccagaacau gaucgucgag gaaugcggcu gcaguugagg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  5792
<211>  1571
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt10)

<400>  5792
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacgguuuac cgggacgagc uuugggugcg gcuuguuugu      120

uauuguuggc agcggguugg uuaggcccgg aagcgugggg aucgccgaca ccucccccua      180

cuccggcggc gccaccgccc ccgccaccgc cggggucgcc aggcgggucc caagauacuu      240

gcacaaguug cggggguuuc cgacgacccg aggaauuggg acgcguagac ggugauuucu      300

uggaagcugu aaagcgucau aucuuaucgc guuuacagau gcgagggcga ccgaacauaa      360

cccacgccgu accgaaggcg gcgaugguua ccgcguuacg aaaguuacau gcugggaagg      420

uucgugagga cgggcgugua gagauccccc auuuggacgg gcacgccucg ccaggggccg      480

acgggcaaga gcgagucucg gagauaauua guuucgcgga gacugacggg uuagcgucgu      540

cgaggguacg uuuauacuuc uucauaucga acgaggguaa ccaaaacuug uucguaguac      600

aggcgaguuu augguuauac cuuaagcuau uaccauacgu uuuagagaag gggucgcguc      660

gaaaaguaag gguaaaggua uacuuccaag agcaagguca cggcgaccga uggaacaugg      720

uagagaagcg gguugaccuu aagcgaagug gauggcacac guucccguua acugaggcaa      780

uacaggcauu auucgagcgu ggagagcgcc gcuuaaacuu agacguacaa ugcgacucgu      840

gccaggaguu ggcagucguc ccaguauucg uagaccccgg ggaggagagu caucgaccgu      900

ucguaguagu acaggcgcgc uuaggugacu cgcgacaccg aauccggaag cgugguuuag      960

agugcgacgg uaggacgaac uugugcugcc gacagcaguu uuuuauagac uuuagguuga     1020

ucggguggaa cgacuggaua auugcgccga caggauacua cgguaacuau ugcgaaggaa     1080

guugcccggc guacuuagcg ggggugccag guucggcauc gucguuccac acugcgguag     1140

uuaaccagua ccgaaugcga ggauugaauc cggggacagu aaacucgugc ugcaucccga     1200

cgaaguuaag uacgaugucg auguuauacu ucgacgacga guacaacaua guaaagcgcg     1260

acgucccgaa caugaucgua gaagagugcg guugcgcgug aggacuagug caucacauuu     1320

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1380

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1440

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1500

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaagaau u                                                          1571


<210>  5793
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt10)

<400>  5793
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcguugaggg uccucuuauu gaccgccuug accuuaugcc      120

auggguuuaa uuuggauacg gagaacgcca ugacguuuca ggagaaugcc aggggguuug      180

ggcagagcgu cgugcaguug caggggagca gggucguggu gggggcgccg caggaaaucg      240

uggccgccaa ucagaggggg agcuuguauc agugugauua uagcacgggc agcugugagc      300

cgauacgcuu acaggugccg guggaggccg ugaauauguc guuaggguug ucguuggcgg      360

cgaccacgag cccgccgcag uugcucgccu gugggccgac ggugcaccaa acguguagcg      420

agaauacgua ugucaagggg uuguguuucu uguucggcag uaauuugagg caacaaccgc      480

agaaguuucc ggaggcguug agggggugcc cccaggagga uucggauauc gcguucuuga      540

ucgaugggag ugggaguauc aucccgcaug auuuuaggag aaugaaagag uucgugagca      600

ccgucaugga gcaguugaaa aagaguaaga ccuuguuuag uuuaaugcag uauucggaag      660

aauuucgcau acauuuuacg uuuaaggaau uucaaaauaa uccgaauccg aggagcuuag      720

ucaagccgau cacccaguug uuggggcgca cccauaccgc gaccgggaua cgcaaagugg      780

ucagggaguu guuuaauauc accaacgggg ccaggaagaa ugcguuuaag auauuggucg      840

ugaucacgga uggggagaag uuuggcgauc cgcucgggua ugaggauguc auaccggagg      900

ccgaucgcga aggggucaua agguauguga uaggggucgg cgaugcguuu aggucggaga      960

agaguaggca agaguugaau accaucgcga guaagccccc gagggaucau guguuucagg     1020

ugaauaauuu ugaggcguug aagacgauac agaaucaguu gagggaaaag aucuuugcga     1080

ucgaggggac gcagacgggg ucgaguucga guuuugagca cgagaugagu caggaggggu     1140

uuucggcggc cauaacgagu aaugggccgu uguugagcac gguggggagc uaugauuggg     1200

ccgggggggu guuuuuguau acgaguaaag agaagaguac cuuuauaaau augacgcgcg     1260

uggacagcga uaugaaugau gccuacuugg gguaugcggc cgccauaauc uugaggaauc     1320

gcguccagag cuugguccuc ggggcgccga gguaucagca uauaggguug gucgccaugu     1380

uuaggcagaa uacgggcaug ugggagucga augccaaugu gaaagggacg cagauagggg     1440

ccuauuuugg ggccagcuug uguagcgucg auguggauag caaugggucg accgacuugg     1500

ucuugauagg ggccccgcau uauuacgaac aaaccagggg ggggcagguc agcgugugcc     1560

cguugccgag ggggagggcg agguggcagu gugaugccgu cuuguacggg gagcaggggc     1620

agccgugggg gcgcuuuggg gcggccuuga cgguguuggg ggaugugaau ggggauaagu     1680

ugacggaugu cgccauaggg gccccggggg aagaggauaa uaggggggcc gucuauuugu     1740

uucaugggac gagugggucg gggauaagcc cgagucauag ccagaggauc gcggggagca     1800

aguuaagucc gcgcuuacag uauuuuggcc agucguugag uggggggcag gauuugacca     1860

uggauggguu ggucgacuua accgucgggg cccagggcca cgucuuguug uugaggaguc     1920

agccggucuu gagggugaaa gccauaaugg aauuuaaccc gagagaggug gccaggaaug     1980

uguuugagug uaaugaucag gucgugaaag ggaaggaggc gggggaggug cgcgucugcu     2040

uacaugucca gaaaucgacc agggacaggu uaagggaggg gcagauacaa agugucguga     2100

cguaugauuu ggcguuggau agugggcgcc cgcauucgag ggcgguguuu aaugagacga     2160

agaacagcac gaggagacag acgcaagucu ugggguugac gcagaccugu gaaaccuuga     2220

aguugcaguu accgaauugc auagaggauc cggugagccc gauagucuug agguugaacu     2280

ucaguuuggu ggggaccccg uugagcgccu uugggaauuu gaggccggug uuggcggagg     2340

augcgcagag guuguuuacg gcguuguuuc cguuugagaa aaauuguggg aaugauaaua     2400

ucugccagga ugauuugucg auaacguuua gcuuuaugag cuuggauugu uuggucgucg     2460

gggggccgag ggaguucaau gugaccguga cgguccgcaa ugauggggaa gacaguuauc     2520

gcacccaggu caccuuuuuu uuucccuugg auuugagcua uaggaaggug agcacguugc     2580

agaaucagag gagccagagg agcuggcgcu uggccugcga gagcgcgagc agcaccgagg     2640

ucucgggggc guuaaagagc acgaguugca guaucaauca uccgauauuu ccggaaaauu     2700

cggaggugac cuuuaauauc accuuugaug ucgauagcaa ggccagcuug gggaauaagu     2760

ugcucuuaaa ggcgaaugug acgucggaga auaauaugcc gcgcaccaau aagaccgaau     2820

uucaguugga guugccggug aaauacgcgg ucuauauggu ggugacgucg caugggguca     2880

guaccaagua uuugaauuuc acggcgucgg agaauaccag ucgcgucaug cagcaucagu     2940

aucaagucag uaauuugggg cagaggucgu ugccgauaag uuuggucuuu uuggucccgg     3000

ugcgcuugaa ucaaaccguc aucugggaua ggccgcaggu caccuuuagc gagaauuuga     3060

guaguaccug ccauaccaag gagagguugc cgucgcacag ugauuucuug gccgaauuga     3120

ggaaggcgcc ggucgucaau uguagcauag ccgucuguca aaggauccaa ugugauaucc     3180

cguuuuucgg cauccaagag gaauuuaaug ccaccuugaa ggggaauuug ucguuugauu     3240

gguacauaaa aacgagccac aaucauuugu ugaucgucag uaccgcggag auauuguuua     3300

augauucggu guuuacccuc uuaccggggc agggggccuu ugucaggagc caaaccgaga     3360

ccaaggucga gccguuugag gugcccaauc ccuugcccuu gauagugggg aguagugucg     3420

ggggcuuguu guuguuggcg uugauaaccg ccgccuuaua caaauugggg uuuuuuaaaa     3480

ggcaguauaa ggacaugaug agugaggggg ggcccccggg cgcggagccg caaugaggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  5794
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt10)

<400>  5794
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuuaguuuaa aaaccuugcc guucuuauug cucuugcacg      120

uccaaaucag uaaagcguuc ccggucagca gcaaggaaaa gaacaccaag accguccaag      180

auuauuuaga gaaauuuuau cagcucccgu cgaaucaaua ccaaagcacc cgcaaaaacg      240

ggaccaacgu cauagucgag aaauugaagg agaugcaaag guucuucggc cucaacguca      300

ccggcaaacc gaacgaagag accuuagaua ugaugaagaa accgaggugc ggggucccgg      360

auucgggggg guucaugcuc acgccgggga auccgaaaug ggagaggacc aaucucacgu      420

aucgcaucag gaauuacacg ccgcaauuaa gcgaagccga agucgagcgc gccauaaaag      480

acgcguucga guuguggucg gucgccagcc cguugauauu uacgcgcaua agccaagggg      540

aagccgacau aaauaucgcc uucuaucagc gcgaccaugg ggauaacagc ccguucgacg      600

ggccgaacgg gauauuggcc cacgcguucc aaccggggca ggggaucggg ggggacgccc      660

acuucgacgc ggaggagacc uggacgaaua cgagugccaa cuauaaucuc uucuuggucg      720

ccgcccacga guucgggcac agccucggcu uggcccauag uagcgauccg ggggcgcuca      780

uguacccgaa uuacgccuuu cgcgagacgu cgaauuauag cuugccgcag gacgauauag      840

acgggaucca agcgauauac ggguugagcu cgaauccgau acagccgacc gggccgucga      900

ccccgaagcc gugcgauccg ucgcucaccu ucgacgccau aacgaccuug aggggggaga      960

ucuuguuuuu caaggaucgc uauuuuuggc gccgccaccc gcaauugcag cgcguggaga     1020

ugaacuucau cagcuuguuu uggccgaguu ugccgaccgg gauccaagcc gccuacgagg     1080

acuucgaucg cgauuugauc uuuuuguuca aggggaauca guauugggcc uuaucggggu     1140

acgacaucuu acagggguac ccgaaagaca ucagcaauua cggguuuccg ucgucggugc     1200

aggccaucga ugccgccguc uuuuaucgcu cgaagaccua uuuuuucguc aacgaucagu     1260

uuuggcgcua cgacaaucag cgccaguuua uggaaccggg guacccgaag ucgaucagcg     1320

gggcguuccc ggggaucgaa ucgaaggucg acgccgucuu ucaacaggag cacuuuuuuc     1380

acguguuuuc ggggccgcgc uacuaugccu ucgacuugau cgcccaacgc gucacgcgcg     1440

ucgcccgcgg gaacaagugg uugaauugcc gcuacgggug aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  5795
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt10)

<400>  5795
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucguuauggc aaccuuuggu auugguauua uuggucuuag      120

ggugcugcuu cgcagcgccg cgucagcgac agucgacauu agucuuguuc ccgggugacu      180

uacgaaccaa cuuaacugau cggcaauuag cugaagagua uuuauacagg uacggcuaca      240

cgcgcguagc ggagaugagg ggggagucua agaguuuagg cccagcauua cucuuguugc      300

agaaacaguu aucguuaccc gaaacggggg aauuagacuc ggcgacacuc aaggcgaugc      360

gcacuccucg uugcggagua cccgacuugg gacgauuuca gacauucgag ggugauuuga      420

aguggcacca ccacaacaua acguacugga uccagaacua cucugaggac uuaccucgug      480

caguaauaga cgacgcuuuc gcacgagcgu ucgcuuuaug gucggccguu acacccuuga      540

cguuuacgcg agucuauucg cgcgacgccg acauaguaau acaguucggg guagccgagc      600

acggugacgg cuacccauuc gacgguaagg acgguuuauu agcgcacgcg uucccgccgg      660

ggccggguau ccagggcgac gcgcacuucg acgacgacga auuauggucu uuagggaaag      720

ggguaguugu accuacgcgu uucgguaacg cggacggugc cgcaugccau uucccguuca      780

uauucgaggg gcgaucauau agugcgugca cuacggacgg acggucggac ggguuacccu      840

gguguucgac uacugcgaac uacgacacgg acgaccgauu cgguuucugc ccgucggagc      900

guuuauacac gcaagacggu aacgcggacg gcaagccuug ccaguucccu uucauauucc      960

agggacaguc guacucggca ugcacaaccg acgggcgguc ggacggguac cgguggugcg     1020

cgacuacggc gaacuacgau cgcgacaagu uauucggguu cugcccaaca cgggcagacu     1080

cuaccguaau gggagggaac agugccggag aguugugcgu auuccccuuc acguucuugg     1140

gaaaagagua cucaacaugc acuucggaag gccgggguga cggucgauug uggugcgcca     1200

cuacgaguaa cuucgacucg gacaaaaagu gggguuucug uccugaccag ggcuauucgu     1260

uauucuuagu agcagcacac gaguucgggc acgcauuagg auuggaccac aguaguguac     1320

ccgaagcauu gauguauccg auguaccgau uuacggaagg uccgccguua cacaaggacg     1380

acguaaacgg uauccgacac uuauacggcc cacggccgga gccggaaccg cgcccaccga     1440

ccacaacgac uccacagccc acugcaccgc ccacaguaug uccuacgggu ccuccgacag     1500

uacacccguc ggagcgaccg acggcagguc ccacuggacc gccgagugca gggccgacgg     1560

ggccgccgac cgcagguccg ucgacggcga caacgguccc guuaucgccc guagacgacg     1620

cgugcaacgu uaacauauuc gacgcaauag cagagauagg uaaccaguua uacuuauuca     1680

aggacggcaa guacuggcgc uuuucggagg ggcgaggaag ucgaccccag gggccguucu     1740

uaaucgcgga caaguggccg gcauuaccuc gaaaguuaga uucaguauuc gaggagcgau     1800

uaaguaagaa auuauucuuc uucucgggua ggcaaguaug gguauauacg ggugccuccg     1860

uauuagggcc ccggaggcuc gacaaguugg ggcucggugc ugacgucgcg cagguaacgg     1920

gugcuuuacg cucgggucga ggaaagaugu uauuauucag uggucgccga uuauggcguu     1980

ucgacguaaa ggcacagaug gucgacccuc gaucggcguc ggaggucgac cguauguucc     2040

cggguguacc guuagacaca cacgacguau uccaguaccg cgaaaaggcu uacuucugcc     2100

aggauagguu cuacuggcga gucucgucga ggucggaauu aaaucaagua gaccagguag     2160

gguaugucac guacgacauc uuacagugcc cggaggacug aggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  5796
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt10)

<400>  5796
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacccgggcg uguuagccgc guuuuuguuu cucucgugga      120

cccacugcag agcguuaccg uugccgucgg ggggggacga ggacgaccuc agcgaagagg      180

auuugcaauu cgccgaaagg uauuuacgca gcuauuauca cccgaccaac uuggccggga      240

uauuaaaaga aaacgccgcc ucgaguauga ccgaacgcuu gagggagaug caaaguuuuu      300

uugggcucga agucaccggg aaguuggaug acaauacgcu cgacgugaug aagaaaccgc      360

gcuguggcgu cccggacguc ggggaguaua acgucuuucc gaggaccuug aaguggagua      420

agaugaaccu cacguaucgc aucgucaacu auacgccgga caugacccac agcgaggugg      480

agaaagccuu uaagaaggcg uuuaaggucu ggagugacgu caccccguua aacuucacgc      540

gcuugcauga cgggaucgcc gauauaauga uuagcuucgg gaucaaagaa cacggggauu      600

uuuauccguu cgacggcccg agcggguuau uagcccacgc cuucccgccg ggcccgaacu      660

acggggggga cgcgcacuuc gacgacgacg agacguggac cucgucgagu aagggguaua      720

aucucuucuu ggucgccgcc cacgaauuug ggcauagucu cggguuggau cauaguaaag      780

auccgggggc cuugauguuc ccgauauaua cguauacggg gaagucgcau uucauguugc      840

cggacgauga cguccagggc auacaaaguu uguacgggcc gggggacgag gauccgaauc      900

cgaagcaccc gaagaccccg gauaagugcg auccgagucu caguuuggac gcgaucacgu      960

cguugagggg ggagaccaug auauucaagg aucgcuuuuu uuggagguua cacccgcaac     1020

aagucgacgc cgaauuauuc cucaccaaga gcuucuggcc ggaguugccg aauaggaucg     1080

acgccgccua cgaacauccg agccacgauu ugauauuuau auuucgcggg cgcaaguucu     1140

gggccuugaa cggguacgau aucuuagagg gguacccgaa gaagaucagc gaguuagggu     1200

ugccgaagga ggucaaaaaa aucucggccg ccguccauuu cgaagacacc gggaaaaccu     1260

uguuauuuag cgggaaucaa guguggcgcu acgacgacac caaucacauc auggacaagg     1320

auuacccccg cuugaucgag gaggauuuuc cggggaucgg ggacaagguc gacgccgugu     1380

acgaaaagaa cggguacaua uacuucuuua augggccgau ccaauucgag uauucgauau     1440

ggucgaauag gaucgucagg gugaugccgg ccaacaguau ccucuggugc ugaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  5797
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt10)

<400>  5797
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaccccga acaccaccga agauuacgac accacaaccg      120

aguucgacua cggcgacgcc acccccugcc aaaaagucaa cgaacgcgcc uucggcgccc      180

aacuccuccc accccuuuac ucccucgucu ucgucaucgg ccucgucggc aauauccucg      240

uaguccucgu ccucguccaa uacaaacgac ucaaaaacau gaccuccauc uacuuacuca      300

acuuagccau cuccgaccuc cucuuccucu ucacccuccc cuucuggaua gacuacaaac      360

ucaaagacga cugggucuuc ggcgacgcca ugugcaaaau ccucucgggc uucuacuaca      420

caggacucua cuccgaaauc uucuucauca uccucuuaac uaucgaccgc uaccuagcca      480

ucguccacgc cgucuucgca cuacgcgccc gcaccguaac cuucggcguc aucaccucaa      540

ucaucaucug ggcccucgcc auccucgccu ccaugcccgg ccucuacuuc ucaaaaaccc      600

aaugggaguu cacacaccac acaugcucac uccacuuccc ccacgaaucc uuacgcgaau      660

ggaaacucuu ccaagcccuc aaacucaacc uauucggccu aguccuccca cuacucguca      720

ugaucaucug cuacacaggc aucaucaaaa uacuccuccg ccgccccaac gaaaagaaau      780

ccaaagcagu ccgccucauc uuugucauaa ugauaaucuu cuuccuauuc uggacccccu      840

acaaccucac cauccucauc ucaguauucc aagacuuccu cuucacccau gaaugcgaac      900

aaucacgcca cuuagaccuc gccguccaag ucaccgaggu cauugccuac acccacugcu      960

gcgucaaccc aguaaucuac gccuucgucg gcgaacgcuu ccgcaaauac cuccgucaac     1020

uauuccaccg acgcgucgcc guacaccucg ucaaauggcu ccccuuccua ucugucgacc     1080

gauuagaacg cgucuccucc acaagcccaa gcaccggcga acacgaacuc uccgccggcu     1140

ucugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  5798
<211>  983
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt10)

<400>  5798
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgaacauuag caugcuuguu guuauuaggu ugcggguacu      120

uagcgcacgu guuagcagag gaggcagaga ucccgcguga gguuaucgag cgcuuggcac      180

gaucgcagau ccacaguauc cgagacuuac agcgguuguu ggagaucgac ucagucggcu      240

cggaggacuc guuagacacg aguuuacgag cgcacggggu gcacgccacg aagcacguac      300

cggagaagcg cccguugccg auacgucgca agcgaucgau cgaggaggcg gugcccgcgg      360

uuugcaagac gcgaaccguc aucuacgaga ucccacgauc gcagguagac ccuaccucgg      420

cuaacuucuu aauauggccu ccaugcguag aggucaagcg uugcacgggg ugcugcaaca      480

caucgucggu uaagugccag ccgucgcgag ugcaccaccg uucgguaaag guggccaagg      540

uugaguacgu acgaaagaag cccaagcuaa aggagguuca gguucgauug gaggagcacu      600

uagagugcgc uugcgccacg acgaguuuga accccgacua ccgugaggag gacacggggc      660

gaccgcgcga gucgggcaag aagcgaaagc gaaagcgguu gaagccgacg ugaggacuag      720

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      780

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      840

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      900

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaga auu                                              983


<210>  5799
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt10)

<400>  5799
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaccguugcu gggcccuuuu cuugucguua ugcugcuacu      120

ugcgcuuggu gucggccgag ggugauccga uaccggagga gcuguacgag augcuaucug      180

accacaguau aaggucauuc gacgacuugc agcgauuauu acacggggac ccgggugaag      240

aggacggggc ggaguuagac uuaaacauga cgcgcucgca cucggguggg gaguuggagu      300

cguuagcgcg ggggcggcga ucguuagggu cguugacgau cgcggagccu gcgaugaucg      360

cggagugcaa gacgcguacg gaggucuucg agauaucgcg acguuuaauc gaccgaacca      420

acgcaaacuu cuuaguaugg cccccuugcg ucgagguaca gaggugcagu ggaugcugca      480

acaaccgaaa cguccagugc aggccgacgc agguucaguu gcguccggua caaguccgua      540

agaucgagau cguccguaag aagccgauau ucaagaaggc uacgguaacc uuagaggacc      600

aucucgccug caagugcgag acugucgccg cggcgaggcc gguaacucgg ucgcccggug      660

ggagucagga gcagcgugcg aagacgccgc agacgcgagu uaccauaagg accguacgug      720

ugcgucgucc gccgaaagga aagcaccgaa aguucaagca cacgcacgac aagacugccu      780

uaaaggagac guuaggugcc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  5800
<211>  1385
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt10)

<400>  5800
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucguuauucg gcuuguuauu auugacgagu gcguuagcag      120

ggcagcggca agguacacag gcagagucga accucucguc gaaguuccag uucucgucga      180

acaaggagca gaacggugug caggacccac agcacgagcg uaucaucacg guuucgacaa      240

acgggucgau acacucgccg cguuucccac acacguaccc gcgaaacacu guguuagucu      300

ggcgucucgu ugccgucgag gagaacguuu ggauccaguu aacuuucgac gagagguucg      360

guuuagagga cccggaggac gacaucugca aguacgacuu cguugaggua gaggagccuu      420

cagacgguac gaucuuggga cgauggugcg ggucggggac cguucccggg aagcagauau      480

cgaaggggaa ccagauacga auccgauucg ucucggacga guacuucccg ucggagccgg      540

guuucugcau acacuacaac auaguaaugc cgcaguucac ggaggccguu ucgccgucug      600

ucuuaccgcc cucggcguua ccguuagacu uacucaacaa cgcgaucacg gcguucucua      660

cguuagagga cuuaauacgu uacuuagagc cggagcgaug gcaauuagac uuggaggacu      720

uguaccgccc caccuggcag uuacucggua aggcauucgu auucgggcga aagagucgag      780

uaguagacuu aaauuuauua accgaggagg uucgacuaua cucuugcacu ccccgcaacu      840

ucucgguuuc gauccgagag gagcuuaagc gcacggacac gauauucugg ccggggugcu      900

uauuggucaa gaggugcggg gguaacugcg cgugcugccu ucacaacugc aacgagugcc      960

agugcgugcc gucgaagguc acaaagaagu accacgaggu cuuacaacuu cgccccaaga     1020

cgggcgugcg agguuuacac aagagucuaa cugacguagc gcucgagcac cacgaggagu     1080

gcgacugcgu cugcaggggg ucgaccgggg ggugaggacu agugcaucac auuuaaaagc     1140

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1200

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1260

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

gaauu                                                                 1385


<210>  5801
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt10)

<400>  5801
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgacuaa ucuucguaua caccuugaua ugcgccaacu      120

ucugcuccug ccgagacacg ucggccacuc cccagucggc uaguauaaag gcccuucgua      180

acgcgaacuu gcgucgggac gaccuuuaca ggagggacga gacuauccag gucaagggca      240

acggauacgu ccaaucgccc cgguucccca acaguuaccc gcggaacuua cuuuugaccu      300

ggcguuuaca cucgcaggag aacacgagga uccaauuagu uuucgacaac caguucggcc      360

ucgaggaggc cgagaacgac auaugccgau acgacuucgu agagguagag gacaucagug      420

agaccucgac gauaaucagg gggcgguggu gcggccacaa ggagguaccc ccucgaauca      480

agagucgaac caaccagauc aagauaaccu ucaagucgga cgacuacuuc guagcaaagc      540

cgggguucaa gauauacuac ucgcucuuag aggacuucca gccggcggcc gcgucggaga      600

caaacuggga gucgguaacg ucgucgauau cggguguguc guacaacuca cccucgguca      660

ccgacccgac cuugauagcc gacgcguuag acaagaagau cgccgaguuc gacacgguag      720

aggacuuguu gaaguacuuc aacccggagu cguggcagga ggacuuagag aacauguacu      780

uagacacgcc gagguacagg gggcggucgu accacgaccg caagucgaag guggacuuag      840

accgacuuaa cgacgacgcg aagcgauacu cgugcacacc ucgaaacuac aguguaaaca      900

ucagggagga guuaaaguua gccaacgucg uauucuuccc gcggugcuua uuaguucagc      960

guugcggggg caacugcggu ugcgggacgg ugaacuggcg aucuugcacg ugcaacucgg     1020

guaagaccgu aaagaaguac cacgaggucc uucaguucga gcccgggcac auaaagcguc     1080

gcggccgugc gaagaccaug gcgcucgugg acauucaacu cgaccaccac gagcguugcg     1140

acugcaucug cucgucgcga ccuccgcguu gaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  5802
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt10)

<400>  5802
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaacgcacu cgaaguuccc ggcggcgggu augaguaggc      120

cguuagacac aucgcuucgu uuaaagacau ucucgucgaa gagugaauac cagcucguug      180

ucaacgcggu ccggaaguug caagaaucag guuucuauug gucggcggua acgggggggg      240

aggcaaauuu auuauugucg gcggagccag cggggacauu cuuaauccgu gacucgucug      300

accagcggca cuuuuuuaca uuaucaguga agacacaauc ggguacgaag aaccuucgaa      360

uacagugcga gggcggaagu uucucguugc agagugaccc gcgaucuaca cagccggucc      420

cucgauucga cugcguauua aaguugguuc accauuacau gcccccaccg ggggcuccga      480

guuucccguc accgccgacg gagccgaguu cggagguacc ggagcagcca ucggcgcagc      540

cuuuaccggg uucgccgccu cgacgcgcgu acuacauaua cucggggggu gaaaagauuc      600

cacucguauu aucgaggccu uuaucgucga acguagcgac acuccaacac uugugccgca      660

agaccguuaa cggacauuua gacucguacg agaaggucac gcaacuccca ggcccgauca      720

gggaguucuu ggaccaguac gacgcuccau uaugaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  5803
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt10)

<400>  5803
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugccgagcg ccgggcaauu ggcguuauuu gccuuaggga      120

ucguccucgc cgccugucaa gcgcucgaaa auucgaccag ucccuuaucg gccgaucccc      180

cggucgccgc cgccgucguc agucacuuca acgauugucc ggacagucau acccaauuuu      240

guuuucacgg gacgugucgc uuccucgucc aagaagauaa accggccugc gugugucaca      300

gcggcuaugu cggggccagg ugcgaacacg ccgauuuguu agcggucguc gccgcgucgc      360

aaaaaaaaca agcgauaacg gcgcucgucg ucgugaguau agucgcguua gccguguuga      420

uaauaaccug cgucuuaauc cauuguuguc aagugaggaa gcauugcgaa ugguguagag      480

cguugauaug uagacaugaa aaaccgucgg cguuguuaaa agggcgcacg gccuguuguc      540

auagcgagac cgucguguga ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  5804
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt10)

<400>  5804
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccccgucug guuuacgauu auuacccuua uuguuacccu      120

uauugugguu auuaguauug acccccgggc gaccggccgc cggcuuaagu acgugcaaga      180

ccaucgacau ggaguuagua aagcggaagc gaauagaggc gauacgaggg cagaucuuau      240

cgaaguuacg auuagccagu ccgcccucgc agggcgaggu accgcccggg cccuugcccg      300

aggccguauu agcguuauac aacaguaccc gagaccgagu agcgggugag ucugcggagc      360

ccgagcccga gcccgaggcc gacuacuacg ccaaggaggu aacacgagua uugaugguag      420

agacccacaa cgagaucuac gacaaguuca agcagaguac gcacucuauc uacauguucu      480

ucaacacgag ugaguuacga gaggcgguuc ccgagcccgu auuauuaagu cgagcggagu      540

uacgauuauu gcgauuaaag uuaaagguag agcagcacgu agaguuauac cagaaguaca      600

guaacaacuc uuggcgauac uuaucaaacc guuuauuagc gccgucugac agucccgagu      660

gguuaucuuu cgacguaacg gggguaguac gacagugguu aagucguggg ggcgagauag      720

agggguuccg auugucagcg cacugcaguu gcgacucucg ggacaacacg uugcagguag      780

acaucaacgg cuucacgacg gggcgacgag gcgacuuagc caccauacac ggcaugaacc      840

gacccuucuu auuauuaaug gccacgcccu uagagcgugc gcagcacuua cagucuaguc      900

gacaccgacg agccuuagac accaacuacu gcuucaguuc gaccgagaag aacugcugcg      960

uacgacaguu auacaucgac uuccgaaagg acuuagggug gaaguggaua cacgagccga     1020

agggcuacca cgcgaacuuc ugcuuagggc ccugccccua caucuggucg uuagacacgc     1080

aguacaguaa gguauuagcc uuauacaacc agcacaaccc cggcgccucg gcggccccgu     1140

gcugcguacc gcaggcguug gagcccuuac ccauaguaua cuacguaggc cguaagccga     1200

agguagagca guuaaguaac augauaguac gaucgugcaa gugcaguuga ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  5805
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt10)

<400>  5805
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uauuaucugc guucuugaua uuacacuuag      120

uuaccguggc auugaguuua uccacuugca guacguuaga cauggaccag uucaugcgaa      180

agcgaauaga ggcuauaagg ggucagauuu ugucgaagcu caaguuaacg ucuccuccgg      240

aggacuaccc cgagccggaa gagguaccgc cggagguaau caguauauac aacucgacgc      300

gagaccuuuu acaggaaaag gcaucgcgac gcgcagcggc gugcgagagg gagcguucgg      360

acgaggagua cuacgcgaag gaaguauaca agaucgacau gccuccguuc uucccgucgg      420

agaacgcgau cccaccuacg uucuaucgac cguacuuccg caucgucagg uucgacguaa      480

gugcgaugga gaagaacgcc ucuaacuuag uaaaggcgga guuucgagua uucagguuac      540

agaacccgaa ggcgcgaguu cccgagcaga ggaucgaguu auaccagauc uuaaagagua      600

aggaccuuac uucgccuacg caacgauaca uagacaguaa gguaguaaag acgcgagccg      660

agggagagug guuaucguuc gacgucacgg acgcggucca cgagugguua caccacaagg      720

accgcaaccu uggcuucaag aucagucucc acugcccgug cugcacauuc gucccuucga      780

acaacuauau aauaccgaac aagucggagg aguuagaggc ucguuucgcg ggaaucgacg      840

ggacgucgac guacacgucg ggagaccaga agacgaucaa gucgacgcga aagaagaacu      900

cgggaaagac accgcacuug uuauuaaugu uguuaccguc guacagguua gagucgcagc      960

agacgaaccg ccgaaagaag cgagcgcuag acgcagcgua cuguuuccga aacguacaag     1020

acaacugcug uuuaaggccc uuauacaucg acuucaagcg cgacuugggu uggaagugga     1080

uccacgagcc uaaggguuau aacgcaaacu ucugcgcagg cgcgugcccc uaccucuggu     1140

cgucggacac ccaacacagu cgaguguuau cucuuuacaa cacgaucaac cccgaggcga     1200

gugccucgcc gugcugcguc ucgcaggacu uggagccauu aacgaucuug uacuacaucg     1260

guaagacgcc uaagaucgag caguuaucga acaugauagu caaaaguugc aagugcucau     1320

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  5806
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt10)

<400>  5806
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacu ugcagagggc guugguagua uuagcguuau      120

ugaacuucgc gacgguaucg uuaaguuuau cgacaugcac gacguuggac uucggccaca      180

ucaagaagaa gcgcguagag gcgauacggg gucagauauu aaguaaguua cgcuugacgu      240

cgccgccgga gccgacggua augacacacg uaccguacca gguauuagcg uuauacaaca      300

guacgaggga guuguuagag gagaugcacg gugagcgcga ggaggguugc acgcaggaga      360

acacggaguc ggaguacuac gcgaaggaga uacacaaguu cgacaugaua caggguuuag      420

cggagcacaa cgaguuggcg guaugcccca aggggauaac gaguaagguc uucagguuca      480

acguaucgag uguagagaag aaccgcacga acuuauucag ggcggaguuc cgaguauuaa      540

gggucccgaa cccgucgagu aagcgaaacg agcagaggau agaguuauuc cagauauuac      600

gccccgacga gcacauagcg aagcagcggu acauaggggg uaagaacuua cccacgcgcg      660

guacggcuga gugguugucg uucgacguaa cagacacggu aagggagugg uuauuacgca      720

gggagaguaa cuugggcuua gagauaucga uacacugccc uugccacacg uuccagccga      780

acggggacau auuagagaac auacacgagg uaauggagau aaaguucaag gguguagaca      840

acgaggacga ccacgggcga ggggacuugg ggagguuaaa gaagcagaag gaccaccaca      900

acccccacuu aauauugaug augauaccgc cgcaccgauu agacaacccc ggucaggggg      960

ggcagcgaaa gaagagggcg uuagacacga acuacugcuu ccgaaacuug gaggagaacu     1020

gcugcguaag gccguuauac auagacuucc gccaggacuu aggguggaag uggguacacg     1080

agccgaaggg uuacuacgcu aacuucugca gugguccgug ccccuacuug aggucggcag     1140

acacaacgca caguacggua uuagguuuau acaacacguu gaacccggag gcgucggcua     1200

guccgugcug cguaccgcag gacuuagagc ccuuaacaau auuguacuac guagggagaa     1260

cgccgaaggu agagcaguua ucgaacaugg uaguaaaguc gugcaagugc aguugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  5807
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt10)

<400>  5807
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccccggugg cggucugggc ggcuuuagcg guagggcuug      120

agcuuugggc ggccgcgcac gcguuaccgg cgcaggucgc guucacgccc uacgcucccg      180

agccggguuc aacgugcagg uugcgcgagu acuacgacca aacugcgcag augugcugcu      240

cgaagugcuc cccgggacag cacgcgaagg uauucugcac caaaacauca gacacggugu      300

gcgacucgug cgaggacucg acuuacacgc aauuauggaa cugggugccc gagugccucu      360

cgugcggauc gcgaugcucg ucagaccaag uagagaccca ggccugcacg cgcgagcaaa      420

accggaucug cacgugccgc ccgggcuggu acugcgccuu gucgaagcag gaggguugcc      480

gacucugcgc gccccuccga aagugccggc cggguuucgg gguagcgcga ccugggacgg      540

agacgucgga cguagucugc aagccgugcg cgcccggaac auucucuaac acgacaucgu      600

cuaccgacau cugccgcccg caccagaucu gcaacgucgu ugcaaucccg gggaacgcga      660

guauggacgc gguaugcaca ucgacgucgc cgacgcgcuc aauggcgccg ggcgccgugc      720

accuuccgca gcccguaucg acgcggucgc agcacaccca accgacgccg gagccgucga      780

ccgcgccguc gacuucguuc cuuuuaccca uggggcccuc gccgcccgcg gagggcucga      840

ccggugacuu cgcguugccg guaggguuaa ucgugggcgu cacggcguua ggguuguuaa      900

ucaucggcgu cguaaacugc gugauaauga cgcagguaaa gaagaagccg cugugcuugc      960

agcgagaggc gaaggugccg cacuuaccgg ccgacaaggc ccguggcacg cagggucccg     1020

agcagcagca cuuauuaauu accgcgccgu cgucgaguuc gaguucguug gagucgagcg     1080

caucggcccu agacaggcga gcccccacgc gaaaccagcc gcaggcgccg gguguggagg     1140

cgucuggggc cggcgaggcc cgugccucga ccggaucguc ggacucgucg ccgggcggac     1200

acgguacaca gguaaacgua acuugcaucg uuaacguaug cucgucgucg gaccacucga     1260

gucagugcuc gagucaggcg ucgucgacga ugggggacac ugacucgucg cccucagaga     1320

guccuaagga cgagcagguc ccguucucga aggaggagug cgccuuccgu agucaacucg     1380

agacaccgga gacgcuccuc ggaucaacgg aggagaagcc guuacccuua ggcguuccgg     1440

acgcggggau gaagccgucg ugaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  5808
<211>  860
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt10)

<400>  5808
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccguaaugc gcuuauuucc auguuucuug caguuauuag      120

cgggcuuggc cuuacccgca guaccaccgc aacaaugggc ucucucggca gggaacggua      180

guucggaagu ugaggucguc ccguuccagg aggucugggg ucgaaguuac ugcagggccc      240

uugagcgccu cguggacgua guaagugagu auccgaguga gguagagcau auguucucgc      300

cuaguugcgu uucuuuauug agguguacag guugcugcgg ugacgagaac uuacacugcg      360

uacccguaga gaccgccaac guaacuaugc aauuauugaa gauucgaucg ggagaccguc      420

caucguacgu agaguuaacc uuuagucagc auguccguug cgagugccgu ccgcuucgcg      480

agaaaaugaa gcccgagcgu cgaaggccua aagggcgcgg gaagcggcgc agggagaaac      540

agcgaccuac ggacugucac uugugcgggg acgcgguccc gcgacgcuga ggacuagugc      600

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau      660

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca      720

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag      780

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaagaauu                                                  860


<210>  5809
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt10)

<400>  5809
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgaccgcc agaccgacac ggcccccucg ccguccuacc      120

accucuuacc cggccggcgc cggaccgugg acgccgcggc cucgcgcggg cagggccccg      180

agcccgcccc cgggggcggg gucgagggcg ugggcgcccg cgggguggcc uuaaaguuau      240

ucguccagcu cuuaggcugc ucccgguucg ggggcgcggu ggugcgggcc ggggaggccg      300

agcccucggg cgccgcgcgc uccgccucgu ccggccggga ggagccccag cccgaggagg      360

gggaggagga ggaggagaag gaggaggagc gcggcccgca guggcgguua ggggcccgca      420

agcccggcuc guggaccggc gaggccgccg ucugcgcgga cuccgccccc gccgcccggg      480

ccccgcaggc gcucgcccgc gccucggggc ggggcgggcg cguggcccgg cgcggcgccg      540

aggaguccgg gccgccccac ucgcccuccc ggcgcggcuc ggcgucccgg gccggccccg      600

ggcgcgccuc ggagaccaug aacuucuuau uauccugggu gcacuggucg cucgccuuau      660

uacucuacuu acaccacgcc aagugguccc aggcggcccc gauggccgag ggcgggggcc      720

agaaccacca cgaggucgug aaguucaugg acguguacca gcgcucguac ugccacccca      780

ucgagacguu agucgacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      840

ccucgugcgu gccgcucaug cggugcgggg gcugcugcaa cgacgagggc uuagagugcg      900

ugcccaccga ggaguccaac aucaccaugc agaucaugcg caucaagccc caccaggggc      960

agcacaucgg cgagaugucg uucuuacagc acaacaagug cgagugccgg cccaagaagg     1020

accgcgcccg gcaggagaag aaguccgucc gcgggaaggg caaggggcag aagcggaagc     1080

gcaagaaguc ccgguacaag ucguggucgg uguacguggg cgcgcgcugc ugccucaugc     1140

cgugguccuu acccggcccc caccccugcg ggccgugcuc ggagcggcgc aagcacuuau     1200

ucguccagga cccgcagacg ugcaagugcu cgugcaagaa cacggacucg cggugcaagg     1260

cgcgccagcu cgaguuaaac gagcggacgu gccgcugcga caagccgcgg cgcugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  5810
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt10)

<400>  5810
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuucuuau ugucgugggu ccacuggagu uuagcguuau      120

uguuauacuu acaccacgcg aaguggucgc aagcagcgcc gauggcggag gggggugguc      180

aaaaccacca cgagguagua aaguucaugg acguguacca gaggucguac ugccacccga      240

uagagacguu gguagacaua uuccaagagu acccggacga gaucgaguac aucuucaagc      300

cgucgugcgu accguuaaug cgcugcggug guugcugcaa cgacgagggu uuagagugcg      360

ucccuacgga ggagaguaac aucacuaugc agauaaugag gauuaagccg caucaagggc      420

agcacauagg ggagaugucg uucuugcagc auaacaagug cgagugccga ccgaagaagg      480

accgagcgcg acaggagaag aagaguguaa gggguaaagg gaagggucaa aagcgcaaga      540

ggaaaaagag ucgauacaag ucguggucgg uauacgucgg ggccaggugc ugcuuaaugc      600

cguggucguu accagggccg cacccgugcg ggccgugcuc ggagcgcagg aagcacuuau      660

ucguacagga cccacagacg ugcaagugca guugcaagaa cacggacucg cguugcaagg      720

cacgacaguu agaguuaaac gagcgaacgu gccggugcga caagccucga aggugaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  5811
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt10)

<400>  5811
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucgccguuau ugaggagguu auuauuggcg gccuuguuac      120

aauuagcgcc ggcgcaagcg ccggugaguc aaccggacgc gccggggcau caacgcaagg      180

ucgucagcug gaucgacguc uacaccaggg ccacguguca accgagagaa gucgucgucc      240

cgcucaccgu cgaauugaug gggacggucg cgaagcaauu agucccgucg ugugucaccg      300

uccaaaggug cggggggugu uguccggaug acggguuaga augcgucccg accggccaac      360

aucaggugag aaugcaaaua uugaugauaa gauaucccuc gucgcaauua ggcgaaauga      420

guuuagagga gcauucgcaa ugcgaguguc gcccgaagaa gaaagauucg gccgucaaac      480

cggaucgcgc cgcgaccccg caucauaggc cgcaaccgag gagcgucccc gggugggaua      540

gcgcgccggg ggccccgagu ccggccgaua uaacgcaccc gaccccggcg ccggggccga      600

gcgcgcaugc cgccccgucg acgacgucgg cguuaacgcc ggggccggcg gccgcggccg      660

cggaugcggc cgccaguagu gucgcgaaag ggggcgccug aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  5812
<211>  1607
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt10)

<400>  5812
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccucuuag gguucuucag cgucgccugc uccuuacugg      120

cggcggcccu ccugcccggg ccgcgcgagg ccccggcggc ggcggcggcg uucgagagcg      180

gccuggaccu cuccgacgcc gagccggacg cgggggaggc gaccgccuac gccucgaagg      240

acuuagagga gcagcugcgg uccgucagcu ccguggacga gcucaugacc gugcuguacc      300

ccgaguacug gaagauguac aagugccagu ugcgcaaggg cggguggcag cacaaccggg      360

agcaggcgaa ccucaacagc cgcacggagg agaccaucaa guucgcggcc gcccacuaca      420

acaccgagau ccucaagucc aucgacaacg aguggcggaa gacccagugc augccgcgcg      480

aagucugcau cgacgucggc aaagaguucg gcguggccac gaauacguuu uucaagccgc      540

ccugcgucag uguguaucgg ugcgggggcu guuguaacuc cgaaggguua caauguauga      600

auacgucgac cucguauuua ucgaaaacgc uguucgagau caccgucccc uugucccagg      660

ggccgaagcc cgucaccaua ucguucgcga accauaccuc gugucgcugu augagcaagu      720

uagacgugua ucgccaggug cacucgauca uccggcggag uuuacccgcg acguugcccc      780

aaugccaagc cgccaauaaa acguguccga cgaacuauau guggaacaac cauauauguc      840

gcuguuuagc ccaagaggac uucauguuca guuccgacgc cggggacgau agcaccgacg      900

gcuuucacga uauaugcggc cccaauaaag aauuagacga ggaaacgugc caaugcgucu      960

gucgggcggg guugcgcccc gcgucgugcg gcccgcauaa ggagcucgau cggaauagcu     1020

gucaaugcgu gugcaagaau aaguuguuuc cgucgcagug cggggcgaau cgcgaguucg     1080

acgagaauac gugucaaugc gugugcaagc ggacgugucc gcgcaaccag ccguugaacc     1140

ccggcaagug cgcgugcgag ugcaccgagu cgccgcaaaa gugucuccug aagggcaaga     1200

aauuucauca ucagaccugu ucgugcuauc ggcgccccug caccaaucgg caaaaagccu     1260

gcgaacccgg guucagcuac uccgaggagg ucugccgcug cgugcccagc uacuggaagc     1320

gcccgcagau gucgugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1380

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1440

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1500

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   1607


<210>  5813
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt10)

<400>  5813
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagggaau gggucguagu caacgucuuc augauguuau      120

acguacaauu aguacaaggu ucgucgaacg agcacggucc ggucaagcgu ucgucgcaau      180

cgacguuaga gcguucggag cagcagauac gagcggcguc gucguuagag gaguugcuac      240

ggauaacgca cucggaggac uggaaguuau ggcgaugucg auuacgcuua aagucguuca      300

caucgaugga cucgaggucg gcuucgcacc gcucgacgcg guucgccgcg acauucuacg      360

acauagagac guuaaagguc aucgacgagg aguggcagcg cacgcagugc ucgccgaggg      420

agacuugcgu cgaggucgcg ucagaauugg guaagucgac uaacacguuu uucaagccuc      480

cgugcguuaa cgucuuccgu ugcggggguu gcugcaacga ggagucguua aucugcauga      540

acacaaguac gucauacauc ucgaagcaau uauucgagau cucgguccca uuaaccucgg      600

ucccggaguu ggugccggua aagguagcga accacacggg gugcaagugc uuaccgacgg      660

cuccgcgaca cccguacagu auaauacgac ggucgauaca gauucccgag gaggaccgau      720

gcagucacuc gaagaagcua ugcccaaucg acaugcucug ggacaguaac aagugcaagu      780

gcguauuaca ggaggagaac cccuuggcgg ggacggagga ccacucgcac uugcaggagc      840

cggcguugug cggaccgcac augauguucg acgaggaccg gugcgagugc guaugcaaga      900

cuccgugccc gaaggacuug auucagcacc cuaagaacug cucgugcuuc gaaugcaagg      960

agucguuaga gacgugcugc cagaagcaca aguuguucca cccggauaca ugcaguugcg     1020

aggaccgaug cccguuccac acacgacccu gcgcgucggg uaagacggcu ugcgcgaagc     1080

acugccgauu cccuaaggag aagcgagcgg cacagggucc gcacucucgu aagaacccgu     1140

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  5814
<211>  995
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt10)

<400>  5814
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gguaaaggug acccgaaaaa gccacgcggu aagaugaguu      120

cguaugcguu cuucguccaa acgugccgag aggaacacaa gaaaaagcac ccggacgcgu      180

cgguaaacuu cucggaguuc ucaaaaaagu gcuccgaacg cuggaagacg augucggcga      240

aagagaaagg uaaauuugaa gauauggcga aagcggacaa ggcgcgcuac gagagggaga      300

ugaagacaua uauaccgccg aagggugaga ccaagaaaaa guucaaggac ccgaacgcgc      360

cgaagcggcc gccgucugcg uuuuuccuuu ucuguucgga guaccgcccg aagauaaagg      420

gagagcaccc gggccuuucg auaggcgacg uagcgaaaaa guugggugaa auguggaaua      480

acacggcggc ggacgauaaa cagccauaug aaaagaaagc agcgaagcuc aaggaaaagu      540

acgagaaaga uaucgcggca uaucgagcaa aagguaaacc ggacgcggcg aagaaaggug      600

uaguaaaagc agaaaagucg aagaaaaaga aagaggaaga ggaagaugaa gaggacgagg      660

aagaugaaga ggaagaggaa gaugaagagg acgaggacga ggaagaggac gaugacgaug      720

aaugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      780

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      840

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      900

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                 995


<210>  5815
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt10)

<400>  5815
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg aaaccggcuu cgaacacuca ggccucuggg      120

ucuccguacu agccggccuc cuccucggcg ccugccaagc ccaccccauc cccgacuccu      180

caccccuccu acaauucggc ggccaagucc gccaacgcua ccuauacacc gacgacgccc      240

aacaaaccga agcccaccuc gaaauccgcg aagacggcac cgucggcggc gccgccgacc      300

aaucccccga aucccuacua caacucaaag cccucaaacc uggagucauc caaauacucg      360

gcgucaaaac cucccgcuuc cucugccaac gccccgacgg agcccucuac ggcucccucc      420

acuucgaccc agaagccugc ucuuuccgag aacuccucuu agaagacggc uacaacgucu      480

accaaucuga agcccacggc cucccccuuc accuccccgg aaacaaauca ccccaccgcg      540

accccgcacc ccgcggccca gccagauucc ucccccuccc cggccuccca ccagcccucc      600

ccgaaccacc cggcauccuc gcaccccaac cacccgacgu cggcuccucc gacccccucu      660

caauggucgg ccccucccaa ggccgcuccc ccucauacgc cucaugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  5816
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt10)

<400>  5816
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauucguucc cgccguuauu auuauuauua uuuugggggg      120

ucgucagcca uucguuuccg gccaccuugg agacccagga acaggacguc gaucucgugc      180

aaaaguauuu agagaaguau uauaauuuaa aaaacgacgg ccgccagguc gagaaaagac      240

gcaacucggg gccggucguc gagaagcuca aacagaugca agaguuuuuc ggcuuaaagg      300

ucaccggcaa gccggacgcc gagacguuaa aagucaugaa acaaccgcgc ugcggggucc      360

cggacgucgc ccaauucgug uugaccgaag gcaauccgag gugggaacag acccacuuaa      420

cguaucgcau cgagaacuau accccggacc ucccgcgcgc cgacgucgau cacgcgaucg      480

aaaaggcguu ucaguugugg ucgaacguga ccccguuaac cuuuacgaaa gugagcgaag      540

ggcaggccga uauaaugauc agcuucgugc gcggggacca cagagauaau agcccguucg      600

acgggccggg ggggaacuug gcccacgccu uccagccggg gccggggauc gggggcgacg      660

cccacuucga cgaggacgag cgcuggacga auaacuuucg cgaauauaau cuccacaggg      720

ucgccgccca cgaguugggg cacagcuugg gguugaguca cagcaccgac auaggcgccc      780

ucauguaucc gucguauacg uuuucggggg acguccaauu ggcccaagac gauaucgacg      840

ggauacaggc gaucuacggg aggagucaga acccggugca accgauaggg ccgcagacgc      900

cgaaggccug cgauucgaaa uugacguucg acgccaucac caccaucaga ggggagguca      960

uguuuuucaa ggaucgcuuu uauaugagga ccaacccguu uuaucccgag gucgaauuga     1020

acuuuaucag cgucuuuugg ccgcaguuac cgaacggcuu ggaggccgcc uaugaguucg     1080

cggaucgcga cgaggugaga uucuuuaagg gcaacaaaua uugggccguc caagggcaaa     1140

acgucuugca uggguauccg aaagauauau auucgaguuu cggguuuccg cgcaccguca     1200

aacacauaga cgccgccuug agcgaagaga auaccgggaa gacguauuuu uucgucgcca     1260

auaaguauug gcgcuacgac gaguacaaga ggagcaugga cccgggguac ccgaagauga     1320

ucgcccacga uuucccgggg aucgggcaua aggucgacgc cgucuuuaug aaggacgggu     1380

ucuuuuacuu uuuccacggg acccgccagu auaaguucga cccgaagacc aaacgcaucc     1440

ucaccuugca aaaggccaac ucgugguuua auugucgcaa gaacugagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  5817
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt10)

<400>  5817
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcgcaagu gccugagcaa gcggcucaug cuggccauca      120

ccauggccac caucuucacg gugaacucca cccugcccau cuacgcggcc gucgacaaga      180

acaacgccac cgccgccgug cagaacgaga gcaagcgcua caccgugucc uaccucaaga      240

cgcugaacua cuacgaccug gucgaccucc uggugaagac cgagaucgag aaccugccgg      300

accucuucca guacagcucc gacgcgaagg aguucuacgg caacaagacc cggaugagcu      360

ucaucaugga cgagaucggg cgccgggcgc cccaguacac cgagaucgac cacaagggca      420

uccccacgcu gguggagguc gugcgcgccg gguucuaccu gggcuuccac aacaaggagc      480

ucaacgagau caacaagcgg uccuucaagg agcgcgugau ccccagcauc cuggccaucc      540

agaagaaccc gaacuucaag cuggggaccg agguccagga caagaucgug uccgccaccg      600

gccuccuggc cggcaacgag accgccccgc ccgagguggu caacaacuuc acgcccaucc      660

ugcaggacug caucaagaac aucgaccggu acgcccucga cgaccucaag agcaaggccc      720

uguucaacgu gcucgcggcc ccgaccuacg acaucaccga guaccugcgc gccaccaagg      780

agaagcccga gaacacgccc ugguacggga agaucgacgg cuucaucaac gagcugaaga      840

agcucgcccu guacgggaag aucaacgaca acaacuccug gaucaucgac aacggcaucu      900

accacaucgc gccccugggg aagcuccaca gcaacaacaa gaucggcauc gagacccuga      960

ccgaggugau gaaggucuac ccguaccugu ccaugcagca ccuccagagc gccgaccaga     1020

ucaagcggca cuacgacucc aaggacgccg agggcaacaa gaucccccug gacaaguuca     1080

agaaggaggg gaaggagaag uacugcccca agaccuacac guucgacgac ggcaagguga     1140

ucaucaaggc cggggcccgc guggaggagg agaaggucaa gcggcuguac ugggccagca     1200

aggaggugaa cucccaguuc uuccgcgugu acggcaucga caagccccuc gaggagggca     1260

acccggacga cauccugacc auggucaucu acaacagccc cgaggaguac aagcugaacu     1320

ccgugcucua cggguacgac accaacaacg gcgggaugua caucgagccc gagggcaccu     1380

ucuucacgua cgagcgggag gcgcaggaga gcaccuacac ccuggaggag cuguuccgcc     1440

acgaguacac ccacuaccuc caggggcggu acgccgugcc cggccagugg ggccgcacga     1500

agcuguacga caacgaccgg cugaccuggu acgaggaggg cggggccgag cuguucgccg     1560

ggagcacccg caccuccggc auccugccgc gcaagagcau cgucuccaac auccacaaca     1620

cgacccggaa caaccgcuac aagcugagcg acaccgugca cuccaaguac ggggccagcu     1680

ucgaguucua caacuacgcg ugcauguuca uggacuacau guacaacaag gacaugggca     1740

uccucaacaa gcugaacgac cuggccaaga acaacgacgu cgacggcuac gacaacuaca     1800

uccgggaccu cuccagcaac uacgcccuga acgacaagua ccaggaccac augcaggagc     1860

gcaucgacaa cuacgagaac cugaccgugc ccuucguggc cgacgacuac cugguccggc     1920

acgcguacaa gaaccccaac gagaucuacu ccgagaucag cgagguggcc aagcucaagg     1980

acgccaaguc cgaggugaag aagucccagu acuucagcac guucacccug cgcgggagcu     2040

acaccggcgg ggccuccaag ggcaagcugg aggaccagaa ggccaugaac aaguucaucg     2100

acgacagccu caagaagcug gacaccuacu ccuggagcgg guacaagacc cugacggcgu     2160

acuucaccaa cuacaagguc gacuccagca accgggugac cuacgacgug gucuuccacg     2220

gcuaccuccc caacgagggc gacagcaaga acucccugcc guacgggaag aucaacggca     2280

ccuacaaggg gacggagaag gagaagauca aguucagcuc cgagggcagc uucgaccccg     2340

acggcaagau cguguccuac gagugggacu ucggggacgg caacaagagc aacgaggaga     2400

accccgagca cuccuacgac aaggugggga ccuacaccgu caagcugaag gugaccgacg     2460

acaagggcga gagcuccgug agcacgacca ccgccgagau caaggaccuc uccgagaaca     2520

agcugcccgu caucuacaug cacgugccca agagcggggc ccugaaccag aagguggucu     2580

ucuacggcaa gggcaccuac gaccccgacg gguccaucgc cggcuaccag ugggacuucg     2640

gggacggcag cgacuucucc agcgagcaga accccuccca cguguacacg aagaaggggg     2700

aguacaccgu gacccuccgc gucauggaca gcagcggcca gauguccgag aagaccauga     2760

agaucaagau cacggacccg guguacccca ucggcaccga gaaggagccc aacaacagca     2820

aggagaccgc cuccgggccc aucgugccgg gcauccccgu cagcgggacc aucgagaaca     2880

cguccgacca ggacuacuuc uacuucgacg ugaucacccc cggcgaggug aagaucgaca     2940

ucaacaagcu gggguacggc ggcgcgaccu gggucgugua cgacgagaac aacaacgccg     3000

ugagcuacgc caccgacgac gggcagaacc uguccggcaa guucaaggcc gacaagcccg     3060

ggcgguacua cauccaccuc uacauguuca acggcagcua caugccguac cgcaucaaca     3120

ucgagggguc cgucggccgg ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  5818
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt10)

<400>  5818
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggucacga aguuguuacc ggcguuauua uuacaacacg      120

uguuguuaca cuuguuguua uugccgauag cgauaccgua ugccgaaggg cagcgcaagc      180

gccgcaauac cauccacgag uuuaagaaga gugccaaaac cacguugaua aagaucgacc      240

cggccuuaaa aaucaagacg aaaaagguca acaccgccga ucagugcgcc aaccgcugca      300

cccgcaacaa gggguugccg uuuaccugua aagccuucgu cuucgacaag gcccgcaagc      360

aauguuugug guuuccguuu aacucgauga gcucgggggu caagaaggag uucgggcacg      420

aguucgauuu guaugagaau aaggauuaua uccgcaauug uauaaucggg aaagggaggu      480

cguauaaagg gaccgucagc auaaccaaau cggggauaaa augccaaccg uggucgagua      540

ugaucccgca ugagcauucg uuccucccga gcucguacag agggaaggau uugcaagaga      600

auuauugcag gaacccgagg ggcgaggagg gcgggccgug gugcuuuacc ucgaacccgg      660

aagucaggua ugaggugugc gauaucccgc aaugcagcga ggucgagugu augacgugua      720

acggcgaauc guacaggggg uugauggacc acaccgagag cgggaaaauc ugccaaaggu      780

gggaccacca aaccccgcau agacauaaau uucucccgga gcgcuauccg gauaaagggu      840

ucgacgacaa cuacuguagg aacccggacg ggcaaccccg cccguggugu uauaccuugg      900

auccgcauac gaggugggaa uauugcgcca ucaaaaccug ugccgauaac accaugaacg      960

auaccgacgu cccgcucgag accaccgagu guauacaggg gcagggggag ggguaucgcg     1020

ggaccgugaa cacgaucugg aacgggaucc cgugccaaag gugggacagc caauauccgc     1080

augaacacga uaugaccccg gagaacuuua aauguaaaga uuugagggag aacuauugua     1140

ggaacccgga cggcagcgag agcccguggu gcuucacgac cgacccgaau auaagggucg     1200

gguauuguag ucagaucccg aauugcgaca ugagccacgg gcaagacugc uauaggggca     1260

acgggaaaaa cuacaugggg aaucucaguc agacccgcag cggguugacc ugcagcaugu     1320

gggauaaaaa uauggaggau cuccacaggc acauauuuug ggagccggac gccucgaaau     1380

uaaacgaaaa cuauuguagg aacccggacg acgacgccca cgggccgugg uguuauaccg     1440

ggaacccguu gaucccgugg gacuauuguc cgaucaguag gugcgagggg gacacgaccc     1500

cgaccaucgu gaaccucgau cacccgguca ucagcugcgc gaagaccaag cagcucaggg     1560

ucgucaacgg caucccgacc aggaccaaua ucggguggau ggucucgcuc cgcuaucgca     1620

acaagcacau augugggggg agccucauca aagaaucgug ggucuugacc gccaggcaau     1680

gcuuuccgag cagggaucuc aaggacuacg aggccugguu ggggauccac gacgugcaug     1740

ggcgcgggga cgaaaagugu aagcaagucu ugaacgucag ucaauuaguc uacgggccgg     1800

aggggagcga cuuaguccuc augaaauugg cgcgcccggc cguguuagac gacuucgucu     1860

cgaccaucga ccucccgaau uacgggugua ccaucccgga gaaaacgucg uguucggucu     1920

augggugggg guauaccggg cucauaaauu acgacggguu gcucaggguc gcccacuugu     1980

auaucauggg gaacgaaaag uguucgcaac accacagggg caaagucacc uuaaacgaaa     2040

gcgagaucug cgccggcgcc gagaaaaucg ggagcgggcc gugcgaaggc gacuaugggg     2100

ggccguuggu cugcgaacag cacaaaaugc gcauggucuu gggggugauc gucccgggga     2160

gggggugcgc gaucccgaac aggccgggga ucuucgugag ggucgccuac uacgccaagu     2220

ggauccauaa gaucauccuc accuauaaag ucccgcaaag cugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5819
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt10)

<400>  5819
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gguacgugga uacucuucgc gugcuuguua ggugcggcgu      120

ucgcgaugcc guuaccgccg cacccaggcc acccgggaua caucaacuuc ucguacgagg      180

ucuuaacgcc gcucaagugg uaccagagua uccgaccucc uuaccccucg uacggauacg      240

agccgauggg ggguugguua caccaccaga uaauaccagu auugagucag caacacccgc      300

caacgcacac uuuacagccg caccaccaca uccccguagu ccccgcgcag caaccgguca      360

ucccgcaaca gccgaugaug ccgguacccg ggcagcacuc gaugacaccu auccagcacc      420

accaaccgaa cuugccgccg ccggcgcagc aacccuacca gccacagccg guccagccuc      480

aaccccacca gccuaugcag ccucagccgc cgguacaccc gaugcagccg uuaccaccgc      540

agcccccguu accgcccaug uucccgaugc aaccccuccc gccgauguua ccggacuuaa      600

cguuagaggc guggccuucg acggacaaga cgaagcgcga ggagguugac ugaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  5820
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt10)

<400>  5820
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccguugccgc cgcauccggg ucacccgggg uauauaaacu      120

ucucguauga ggucuugacg ccgcucaagu gguaccaauc gauucgcccg ccuuacccga      180

guuaugggua cgagccgaug gggggguggu gaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  5821
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt10)

<400>  5821
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gguacaugga uauuauucgc gugcuugguc ggugcugcau      120

ucgcaaugcc auuaccuccc cacccaggcc acccggggua cauuaauuuc ucguacgagg      180

uauuaacgcc gcuuaaaugg uaccagagua ugaucaggcc gccguacucg ucguacggau      240

acgaacccau gggggguugg uuacaucacc agauaauacc gguagucucg cagcagcacc      300

cguuaacgca cacguugcaa ucgcaccacc acauaccggu aguaccggcg cagcaaccuc      360

gcguuaggca gcaggcguua augccgguac cggggcagca gucgaugaca ccgacccagc      420

accaccagcc gaacuuacca uuacccgcuc aacagccauu ccagccgcaa cccguccagc      480

cgcaacccca ucagccgaug caaccgcaac cgccgguaca gccgaugcag ccguuguuac      540

cgcagccgcc guugccaccc auguucccgu uacgcccuuu accuccgauc uuaccggacu      600

uacacuuaga ggcauggccg gcgacggaca agacgaagca ggaggaggua gacugaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  5822
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt10)

<400>  5822
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccguugccgc cgcacccggg ccauccgggg uacauaaauu      120

uuucguacga agucuugacg ccgcucaaau gguaucaauc gaugauccgc ccgccguaua      180

gcaguuacgg guaugaaccg augggggggu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  5823
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt10)

<400>  5823
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggagucg cgcgauugcc auugcucuua gguuuguuau      120

uauuaccacg cccggggagg ccccucgacu uagcggacua cacguacgac uuggcagagg      180

aggacgacuc ugaaccuuua aacuacaagg acccgugcaa ggcugccgcg uucuuagggg      240

acauagcguu ggacgaggag gacuuacgcg cuuuccaagu ccagcaggcg guugacuuaa      300

ggcgccacac ggcgcggaaa aguucgauca aggcggcggu acccgggaac acaaguacgc      360

cgucgugcca aaguacaaac ggacaaccac agcgcggggc gugcggacgg uggcgaggga      420

ggucgaggag uaggcgagca gccaccucgc gucccgagcg gguauggccg gacgguguaa      480

uuccauucgu aauagguggc aacuucacgg gaagucagcg ggcgguauuc cgccaggcga      540

ugcgacacug ggagaaacac acaugcguua cguucuugga gcgaaccgac gaggacucgu      600

acauaguauu uacguaccgu ccaugcggcu gcugcaguua cguagggcga agggguggcg      660

guccgcaagc gaucucgaua gguaagaacu gcgacaaguu cgguaucgua guucacgagu      720

uaggucacgu uguagguuuc uggcacgagc acacgcgacc ugaccgcgac aggcacguca      780

guauaguccg cgagaacaua cagccgggac aggaguacaa cuucuuaaaa auggagccgc      840

aagagguuga gucguugggu gagacguacg acuucgacuc gauaaugcac uacgcgcgaa      900

acacguucuc gcgcgggauu uucuuagaca caauaguucc gaaauacgag guaaacggcg      960

ucaagccgcc gauaggccag cggacucgcu ugucgaaggg ugacauagcg caggcgcgga     1020

aguuguauaa gugcccggcg ugcggugaga cauuacagga cucgacggga aacuuuaguu     1080

cgcccgagua cccuaacggc uacucggcgc acaugcacug cgucuggcga auaucgguaa     1140

cuccggggga gaagauuauu uuaaauuuca cuucauugga uuuauauagg ucgcgauuau     1200

guugguacga cuacguagaa guaagggacg gguuuuggcg uaaggccccu uugcgugggc     1260

gauucugcgg aucgaaguua ccggagccga uaguaaguac ggacucgcgu uuauggguag     1320

aguuccgaag uucgaguaac uggguaggua aggguuucuu cgccguuuac gaggcaauau     1380

gcggugggga cguaaagaag gacuacgguc auauacaguc uccgaauuac ccggacgacu     1440

acaggccuag uaagguaugu auauggcgca uccaagucuc ggagggauuc cauguugggu     1500

ugacguuuca gaguuucgag auagagaggc acgacucgug cgcguacgau uacuuagagg     1560

uaagggacgg acauucggag ucgaguacuu uaauaggacg auacugcggu uacgagaagc     1620

cggacgacau aaagucgacu ucgucgcgau ugugguuaaa guucguuucg gacggaagua     1680

uaaacaaggc agguuucgcg guuaacuucu uuaaggaggu agacgagugc ucgcgaccga     1740

accgaggcgg uugcgagcaa cgaugcuuaa acacguuggg aucuuacaaa ugcucuugcg     1800

acccggguua cgaguuggcg ccggauaaga ggcgaugcga ggcggcaugc ggggguuucu     1860

uaacaaaguu gaacgguucg auaacaucgc ccggguggcc gaaggaguac ccgccgaaca     1920

agaacugcau auggcaauua gucgcgccga cacaauaccg gauuucguua caguucgacu     1980

ucuucgagac ggaggguaac gacgucugua aguacgacuu cgucgagguc cgaucggguu     2040

ugacugcgga cucaaaguua cacgguaagu ucugcggcuc ggagaagccg gagguaauua     2100

caucgcagua caacaacaug cgagucgagu ucaagucgga caacacggua aguaagaagg     2160

gguucaaggc acacuucuuc ucggauaagg acgaguguuc gaaagacaac ggggguugcc     2220

aacaggacug cguaaacacc uucgguucgu acgaguguca gugccgaucg gguuucguau     2280

uacacgacaa caagcacgac ugcaaggagg caggaugcga ccauaagguc acgucgacuu     2340

cggggacgau aacgucgccg aacuggccgg acaaguaccc gucgaagaag gagugcaccu     2400

gggcgaucuc gucaacuccg ggucaucgag uuaaguugac guucauggag auggauauug     2460

agucgcagcc cgagugcgcg uacgaccacu uagagguauu cgacgggcgu gacgcgaaag     2520

caccgguauu aggaagguuc ugcgguucga agaaacccga accgguuuug gcgacgggaa     2580

gucguauguu cuuacgguuc uacucggaca auaguguaca acguaagggg uuccaagcau     2640

cgcaugcgac ggagugcggu ggucaggucc gagcggacgu uaaaacgaaa gacuuauacu     2700

cgcacgcgca guucggggac aauaacuacc cgggcggggu ugacugcgag uggguuauag     2760

ucgcagagga gggguacggu guagaguuag uauuccagac uuucgagguc gaggaggaga     2820

cggacugcgg uuacgacuac auggaguuau ucgacgguua cgacucgacg gcgccacgau     2880

uagguaggua cugcgggucg ggaccgccgg aggagguaua cucagccggu gacaguguau     2940

uagucaaguu ucacucugac gacacgauaa cgaagaaggg cuuccacuua cguuacacga     3000

guacgaaguu ccaggacacg uuacacucuc gaaagugagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  5824
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt10)

<400>  5824
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgcgggca cgagguguuu guuggcacuc uuauugccgc      120

aaguauuguu agggggggcc gcgggguugg uccccgaguu agggaggcgc aaguucgccg      180

ccgcaagcag cgggaggccg agcagucagc cgagcgacga gguauuaucg gaguucgagc      240

ucagauuauu gucgauguuc ggguuaaaac aacgcccgac gccgucgcgc gacgcggucg      300

ucccgccgua uauguuggac uuauauaggc gccacagcgg gcagcccggg agcccggcgc      360

cggaccacag acucgagcgc gcggcgucga gggcgaacac ggucaggucg uuccaccaug      420

aagaaagccu cgaagaauug ccggaaacau cgggcaaaac gacgagacgc uucuucuuua      480

aucucucgag cauaccgacc gaggaguuua uaacgagcgc cgaguugcaa gucuucaggg      540

aacagaugca agaugcgcuc gggaacaauu cgucguucca ucacaggaua aauauauaug      600

aaauaauuaa accggccacg gcgaacagca aauucccggu cacgcgcuug cucgacacgc      660

gccucgucaa ucagaaugcg ucgcgcuggg aaucguuuga uguaacgccg gcggucauga      720

gauggaccgc ccaggggcac gcgaaccaug gguucgucgu cgaagucgcg caccucgagg      780

agaaacaagg gguaaguaag cgccaugucc gcauuucgcg cagccuccac caagaugaac      840

acucguggag ccagauucgc ccgcucuugg ucacguuugg gcaugauggg aaaggccauc      900

cguugcacaa acgcgaaaaa aggcaagcga aacacaaaca aagaaaaagg uugaagaguu      960

cguguaagcg ccacccgcuc uacgucgacu ucucggacgu cgguuggaau gacuggauag     1020

ucgccccgcc uggcuaucac gcguuuuauu gccacgggga augcccguuu ccguuagccg     1080

aucauuuaaa caguacgaau caugcgauag uccagacacu cguaaacagc gucaacagca     1140

agauaccgaa agcgugcugu guacccacgg aauugucggc gauaagcaug uuauauuugg     1200

acgagaauga aaaggucguc cucaaaaauu aucaggacau ggucgucgag ggguguggcu     1260

guaggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  5825
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt10)

<400>  5825
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaccgggaa acaggauguu aaugguagua uuguugugcc      120

agguauuauu ggguggugcc ucgcacgcga guuugauccc ggagaccggu aagaagaagg      180

uagcggagau ccagggccac gcggggggcc gacguagcgg ucagucgcac gaguuauugc      240

gagacuucga ggccacgcuc uuacagaugu ucggucuucg ccgaaggccg cagccgucua      300

agucggccgu cauacccgac uacaugcgag acuuauaccg auuacagucg ggcgaggagg      360

aggaggagca gauccacagu acgggguuag aguacccgga gcguccggcc ucgcgagcga      420

acacgguccg cucguuccac cacgaggagc acuuggagaa cauaccgggc accucggaga      480

acagugcguu cagauucuua uucaacuuau cgaguauccc agagaacgag gugauaucua      540

gugcggaguu gcgcuuauuc cgugagcagg uugaccaagg gccggacugg gagcgcggcu      600

uccaccgaau caacaucuac gaggugauga agccgccggc ggagguagua cccggucacu      660

uaaucacucg ucucuuagac acgcgauuag uacaccacaa cguaacgagg ugggagacgu      720

ucgacgucag uccggcggua uugaggugga cgcgcgagaa gcagcccaac uacggauuag      780

cgaucgaggu cacgcaccua caccagaccc guacgcacca gggccagcac guccgaauau      840

cgcgaucgcu accgcaggga ucggguaacu gggcgcaauu aagaccguug uuaguaacgu      900

ucggccacga cgggcgaggc cacgcuuuaa cgcgucgacg acgugcgaag cgcucgccga      960

agcaccacuc gcagcgagcg cgaaagaaga acaagaacug ccgacgucac agucuuuacg     1020

uugacuucuc ggacgucgga uggaacgacu ggauaguugc gccgccgggc uaccaggcgu     1080

ucuacugcca cggggacugc ccguucccgu uagccgacca cuuaaacagu accaaccacg     1140

ccaucgucca gacgcuugua aacucgguaa acaguucaau acccaaggcg ugcugcguac     1200

ccacggaguu aagugcgauc ucgauguuau acuuggacga guacgacaag guuguuuuaa     1260

agaacuacca ggagaugguu guggagggcu gcggaugccg uugaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  5826
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt10)

<400>  5826
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcuuag gcagacgcgc ccaaugguua uguugguggu      120

ggggcuuauu auguucgugu uguggcccgc cccccuuaag acccccgcuc ccggccgcgg      180

ccgcggcggc ggcgggcggc caauuauuag gcgauggggg cucgccgggg aggaccgaac      240

aacccccccc cagcccccaa aguaguagcg gguuuuuaua uagaagauug aaaacccaag      300

aaaaaagaga aaugcaaaaa gaaauacuca gcgucuuagg cuugccccau agaccgagac      360

cguuacaugg guugcagcaa ccccaaccgc ccgccuugag acaacaagaa gaacaacaac      420

aacaacaaca auuaccgagg ggggaaccgc cgccgggcag guuaaaaagu gccccguugu      480

uuauguuaga cuuauauaau gcguuaagug cggauaauga ugaagauggc gccagcgaag      540

gcgaacgcca acaaaguugg ccgcaugagg ccgcgucgag cagucaaagg agacaacccc      600

cgcccggggc ggcccauccc uugaauagga aaucguuguu agcgccgggg agcgggucgg      660

ggggggccag uccguuaacg ucggcccaag auucggcguu uuugaaugau gccgauaugg      720

ugaugucguu cgucaauuua gucgaauaug auaaagaauu uaguccgagg caaaggcauc      780

auaaggaauu uaaauuuaau cucagucaaa ucccggaagg ggaagucguc accgccgccg      840

aguuuaggau auauaaagau ugcgucaugg gcucguucaa gaaucagacc uucuugauau      900

cgaucuacca ggugcuccaa gaacaccaac aucgcgauag cgauuuauuc cuccucgaua      960

cgagggucgu cugggcgagc gaggaggggu gguuagaguu cgauauaacc gcgaccucga     1020

acuuaugggu cgucaccccg caacacaaua ugggcuugca auuaucgguc gucacccgcg     1080

acggggugca ugugcauccg agggcggccg gguuagucgg gcgcgauggg ccguaugaua     1140

aacaaccguu uauggucgcc uuuuuuaagg ucucggaagu ccaugucagg acgacgcgca     1200

gcgcgaguuc gagaaggagg cagcaaucga ggaacaggag cacgcaaagu caagaugucg     1260

ccagagugag uucggccagc gacuauaauu cgucggagcu caagaccgcg ugucgcaaac     1320

acgaauuaua cgucucguuu caggauuuag gguggcaaga uuggauaauc gccccgaaag     1380

gguacgccgc gaacuauugc gacggggagu guaguuuucc guugaaugcc cauaugaacg     1440

ccacgaauca ugccaucguc caaacgcucg uccauuugau gaauccggaa uacgugccga     1500

agcccuguug cgccccgacc aaauugaacg cgauaagcgu cuuguauuuc gacgauaaua     1560

guaacgugau cuuaaagaag uaucgcaaca uggucguccg cgccugcggg ugucauugag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  5827
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt10)

<400>  5827
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacguaagau cguuacgagc ggcggcuccg cacaguuucg      120

uagcguugug ggccccguua uucuuauugc gaucggcguu agcggacuuc aguuuagaca      180

acgagguaca cucgaguuuc auacaccgaa gauugcgcuc gcaggagagg cgcgagaugc      240

agcgagagau auuaaguaua uuaggguugc cgcaccgacc caggccccac uugcagggga      300

agcacaacuc ggcuccaaug uucauguuag acuuauacaa cgcgauggcg guagaggagg      360

gggggggucc cgggggucag ggcuucaguu accccuacaa ggcgguauuc ucuacgcagg      420

guccgccguu agcgaguuua caggacucgc acuucuugac ggacgcggac augguaauga      480

guuucguaaa cuuaguagag cacgacaagg aguucuucca cccgcgauac caccacaggg      540

aguuccgauu cgacuuaucg aagauacccg agggggaggc gguaacggcg gcggaguuca      600

ggauauacaa ggacuacauc cgagagagau ucgacaacga gacguuccga auaaguguau      660

accagguauu gcaggagcac uuagguaggg agucggacuu auucuuguua gacagucgca      720

cguuaugggc gucggaggag gguugguugg ucuucgacau aacggcgacg aguaaccacu      780

gggucguaaa ccccaggcac aacuuagguu uacaguuguc gguagagaca uuagacgguc      840

agucgauaaa cccgaaguua gccggguuga ucggucgaca cggcccgcag aacaagcagc      900

cguucauggu agccuucuuc aaggcgacgg agguacacuu caggaguaua aggucgacgg      960

guaguaagca gcgaucgcag aacaggagua agacaccaaa gaaccaggag gcguuaagaa     1020

uggcgaacgu agcugagaac ucgaguucgg accagaggca ggcgugcaag aagcacgagu     1080

uauacguaag uuuccgcgac uugggguggc aggacuggau aauagcgccg gagggguacg     1140

cagcguacua cugcgagggu gagugcgcgu uccccuuaaa cucguacaug aacgcgacga     1200

accacgcgau aguacagacg uuaguacacu ucaucaaccc ggagacagua ccgaagccgu     1260

gcugcgcgcc gacgcaguug aacgcgauaa guguauuaua cuucgacgac ucgaguaacg     1320

uaaucuuaaa gaaguacagg aacaugguag uacgagcgug cgguugccac ugaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  5828
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt10)

<400>  5828
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggcgucgg ccgcguuacu augcuuauua cuuaccgccg      120

cggcguucuc gccgcagggc uuagcgcaac cgguagguau aaacaccagu acgacaugcu      180

gcuacagguu cauaaacaag aagaucccga agcagcgauu agagaguuac cgucguacga      240

cgagcucuca cugcccgcgu gaggcgguca uauucaaaac gaaguuagac aaggagauau      300

gcgcagaccc cacccagaag uggguacagg acuucaugaa gcacuuagac aagaagacgc      360

agacgccuaa guugugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  5829
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt10)

<400>  5829
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuauugaccu ugauaaucuu acucccgguc gucagcaagu      120

ucucguucgu cucguugagc gccccccaac auuggucgug cccggagggg accuuggccg      180

ggaacggcaa caguaccugc gucgggccgg ccccguuucu caucuuuagu cacgggaacu      240

cgauauuccg caucgauacc gaggggacga acuacgaaca gcucgucguc gacgccgggg      300

ugagcgucau aauggacuuc cacuacaacg aaaagcgcau auacuggguc gaccucgagc      360

gccaguugcu ccagcgcguc uucuuaaacg gcagccgcca ggaacgcguc ugcaacaucg      420

aaaagaacgu cagcgggaug gccaucaacu ggaucaacga ggaggucauc uggagcaacc      480

agcaagaggg gauaaucacc gucaccgaca ugaaggggaa caacagucau aucuugcucu      540

cggcccucaa guacccggcc aacgucgccg ucgacccggu cgagcgcuuc aucuucugga      600

gcagcgaagu cgccgggucg uuguaccgcg ccgacuugga cggggucggg gucaaagccu      660

uacucgaaac cagcgaaaag aucaccgccg ucagccucga cgucuuggac aaaagauuau      720

ucuggaucca auauaaucgc gaggggucga acagcuugau cuguaguugc gacuacgacg      780

gggggagcgu gcauaucucg aagcacccga cccaacacaa ccucuucgcc augaguuugu      840

ucggggauag gauauuuuac agcaccugga agaugaaaac caucuggauc gcgaauaagc      900

auaccgggaa agauaugguc cgcaucaauu ugcacagcag cuucgucccg uugggggagu      960

uaaaggucgu ccacccguug gcccagccga aagccgagga cgauaccugg gaaccggaac     1020

aaaaguugug uaagcuccgc aaggggaauu guucgucgac cgucugcggc caggauuugc     1080

aaagccaucu cuguaugugc gccgaagggu augcguuguc gagggauaga aaauauugcg     1140

aggacgucaa cgagugcgcc uucuggaacc acgggugcac cuugggcugc aagaauacgc     1200

cggggaguua cuauuguacc uguccggucg gguucgucuu auugccggac ggcaagaggu     1260

gccaccaguu ggucaguugc ccgaggaacg ucagcgagug uucgcacgau ugcgucuuaa     1320

ccagcgaggg gccgcucugc uuuugcccgg aggggagcgu cuuggaacgc gacggcaaga     1380

ccugcucggg gugcaguagc ccggacaacg gggggugcuc gcaauugugu gucccguugu     1440

cgccggucag uugggagugc gacuguuucc cgggcuacga uuugcaguua gacgagaagu     1500

cgugcgccgc cagcgggccg cagccguucc ucuuauucgc gaacagccag gacaucaggc     1560

auaugcacuu cgacgggacc gauuacggga ccuuauuguc gcaacaaaug gggauggucu     1620

acgcguugga ccacgauccg gucgagaaca aaaucuauuu cgcgcacacc gcguuaaaau     1680

ggaucgaacg cgccaacaug gacgggaguc aaagggagcg cuugaucgaa gagggggucg     1740

acgucccgga gggguuggcc gucgauugga ucgggaggcg cuuuuacugg accgaucgcg     1800

gcaagagcuu aaucgggcgc ucggaccuca acggcaagag gaguaagauc auaaccaaag     1860

aaaauauaag ccagccgagg gggaucgccg uccacccgau ggcgaaacgc cucuuuugga     1920

ccgacaccgg caucaacccg aggaucgagu cgagcaguuu gcagggguug gggagguuag     1980

ucaucgcguc gagcgacuug auauggccgu cggggaucac caucgauuuu cucaccgaua     2040

aacucuauug gugugacgcg aaacaaagcg ucaucgagau ggcgaacuua gacgggagca     2100

agaggaggcg cuugacgcaa aacgacgucg ggcauccguu cgccgucgcc gucuucgaag     2160

acuacgucug guuuagcgac ugggccaugc cgagcgucau gcgcgucaau aaacgcaccg     2220

ggaaggaccg cgucagguug caggggucga uguuaaaacc gagcagcuua gucgucgucc     2280

acccgcucgc caagccgggg gccgacccgu gucucuacca gaaugggggg ugcgagcaca     2340

ucuguaagaa acgcuugggg accgccuggu gcagcugcag ggagggguuc augaaggcga     2400

gcgacggcaa gaccugcuua gccuuagacg ggcaccaauu acucgccggg ggggaggucg     2460

acuugaaaaa ucaggucacc ccgcucgaua uacucaguaa aacccgcguc agcgaggaca     2520

auaucaccga gagccagcau auguuggucg ccgagauaau ggucagcgac caggacgauu     2580

gcgccccggu cggguguucg auguacgcca gaugcaucag cgaaggggaa gacgcgaccu     2640

gccaaugccu caagggguuc gccggcgacg ggaaguugug cagcgacauc gacgagugcg     2700

aaaugggggu gccggucugu ccgccggcga guaguaaaug uauaaauacg gagggggggu     2760

acguguguag auguagcgag ggguaucagg gggacggcau ccauugcuug gacaucgacg     2820

aaugucaguu aggcgaacau ucgugcgggg aaaacgcguc guguaccaac accgaagggg     2880

gguacacgug uaugugcgcc gggagguuaa gcgagccggg guuaaucugu ccggauagca     2940

ccccgccgcc gcauuugcgc gaggacgauc aucauuacag uguccgcaac ucggauagcg     3000

agugcccguu aagucaugac ggcuauuguu ugcacgacgg ggucuguaug uacaucgagg     3060

cccucgauaa auacgccugu aauugcgucg ucggguauau aggcgaaagg ugccaauaua     3120

gggauuuaaa auggugggag uuaaggcaug ccgggcaugg ccaacaacaa aaagugauag     3180

ucgucgccgu gugugucguc gucuugguga uguuauuguu guuaucguua uggggcgcgc     3240

auuauuaucg cacccaaaaa uuauugagca agaauccgaa aaacccguac gaagaaagcu     3300

cgcgcgacgu ccgcucgagg cgcccggccg auaccgaaga cggcaugagu agcuguccgc     3360

agccgugguu cgucgucauc aaggagcauc aggauuugaa aaacggcggg cagccggucg     3420

ccggggaaga cgggcaagcc gccgacggca gcaugcagcc gaccagcugg cgccaagaac     3480

cgcaacucug cgggaugggg accgaacagg gguguuggau cccggucagu ucggacaaag     3540

ggaguugccc gcaagucaug gaaaggucgu uccacaugcc gaguuacggc acccaaacgu     3600

uggagggcgg gguggaaaaa ccgcacagcu uguugagcgc caauccgcuc uggcagcagc     3660

gcgcguuaga uccgccgcau cagauggaau uaacccaaug aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  5830
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt10)

<400>  5830
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acggccggcc gccgcaugga aauguugugc gcggggcgcg      120

ugccggccuu auuauugugu uuaggguuuc acuuguugca agccguguug ucgaccaccg      180

ucaucccgag cugcauaccg ggggaaaguu cggacaauug uaccgcccuc guccaaaccg      240

aggauaaccc gagggucgcc caggucagca ucaccaaaug cucgagcgau augaacgggu      300

acugccucca cgggcaaugu auauacuuag ucgauauguc gcagaauuau ugucgcugcg      360

aggucgggua caccggggug aggugcgagc auuuuuuccu cacggugcau cagccgcucu      420

cgaaggagua cgucgcccuc acggucaucu ugaucauccu cuucuugaua accguggugg      480

ggaguaccua cuacuuuugu cgcugguauc gcaacaggaa gucgaaggag ccgaaaaaag      540

aguacgaacg cgucacgagc ggcgacccgg aacuccccca ggugugagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  5831
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt10)

<400>  5831
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcggagggug agauaacgac guucacugcg uuaacggaga      120

aguucaacuu accgccgggu aacuacaaga agcccaaguu guuauacugc ucgaacgggg      180

ggcacuucuu acgaauauua ccagacggca cgguagacgg uacccgagac cggucggacc      240

agcacaucca guuacaauua ucggcggaga guguuggcga gguauacauc aagucgacug      300

agacagggca guacuuggcg auggacacgg acggguuauu guacgggagu caaacgccga      360

acgaggagug cuuauucuua gagcgcuugg aggagaacca cuacaacacg uacaucucga      420

agaagcacgc ggagaagaac ugguucguag gguuaaagaa gaacgguagu ugcaagcggg      480

ggccacgcac gcacuacggu cagaaggcga ucuuauucuu gccguuacca guaucgagug      540

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  5832
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt10)

<400>  5832
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggcgucg ggggcgggga cguggaggac gugaccccgc      120

gcccgggcgg gugccagauc ucgggccggg gcgcccgcgg gugcaacggc auccccgggg      180

ccgcggccug ggaggccgcc cugccccggc gccggccccg ccggcacccg uccgucaacc      240

cccgcucgcg ggccgcgggc ucgccccgca cccgggggcg ccggacggag gagcgccccu      300

ccggcucccg gcucggcgac cgcgggcggg gccgcgcccu gcccgggggc cggcugggcg      360

ggcgcggccg ggggcgcgcc cccgagcgcg ugggcgggcg gggccgcggc cgggggaccg      420

ccgcgccccg cgccgccccc gccgcccggg gcucgcgccc ggggcccgcg ggcaccaugg      480

ccgccggguc caucaccacg cuccccgccc ugcccgagga cggcggcucg ggggccuucc      540

cgcccggcca cuucaaggac cccaagcggc uguacugcaa gaacgggggc uucuuccucc      600

gcauccaccc cgacgggcgg guggacggcg uccgcgagaa guccgacccg cacaucaagc      660

ugcagcugca ggcggaggag cggggcgugg ugucgaucaa gggggucugc gccaaccgcu      720

accucgccau gaaggaggac ggccggcugc uggccuccaa gugcgugacc gacgagugcu      780

ucuucuucga gcgccucgag ucgaacaacu acaacaccua ccggucccgc aaguacaccu      840

cgugguacgu ggccuuaaag cggacggggc aguacaaguu aggcuccaag accggccccg      900

ggcagaaggc gauccucuuc uuacccaugu cggccaaguc cugaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  5833
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt10)

<400>  5833
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uauuaacgug gauauugccg acguuauuau      120

acaggucgug cuuccacaua auaugcuugg ucgggacaau aaguuuagcg ugcaacgaca      180

ugacgcccga gcaaauggcg acgaacguaa auugcucgag uccggagaga cacacgaggu      240

cguaugacua uauggagggg ggcgacauaa gagucaggag auuauucugc aggacacaau      300

gguauuugag aauagacaag aggggcaaag ucaaggggac gcaagagaug aaaaacaacu      360

auaacauaau ggagauaaga acgguagccg ucggcauagu cgcgauaaaa gggguagaga      420

gugaguucua uuuagcgaug aacaaggagg ggaaguuaua ugcgaagaag gagugcaacg      480

aggacugcaa uuucaaggag uugauauuag agaaccacua uaacacguac gcgucggcca      540

aguggacaca caacggcggg gagauguucg ucgcguuaaa ccaaaagggc auaccgguca      600

gggggaagaa gacgaagaaa gagcaaaaga cggcgcacuu cuugccgaug gcgauaacgu      660

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  5834
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt10)

<400>  5834
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguuguuac ccucaguugu acucaaauua uucuuagcgg      120

ccguauuaag ugcucuugug accggcgagu cguuggagcg uuugcgccgc ggucuugcag      180

cgggcacgag uaacccggac ccgccgacgg ucucgaccga ccaguuacuc ccucucgggg      240

gcgggcgcga ccguaagguu cgggaccucc aggaggcgga cuuagaccuc cuacguguua      300

cgcuuucguc gaagccccag gccuuggcga ccccuaacaa ggaggagcac gguaagcgua      360

agaagaaggg gaaggggcuu ggcaagaagc gugacccgug cuugcgaaag uacaaggacu      420

ucugcauaca cggggagugc aaguacguca aggaguuacg agcgccgagu ugcaucugcc      480

acccgggcua ccacggggag cgaugccacg gcuugucguu accgguagag aaccguuugu      540

acacuuacga ccacacuacc auacucgccg uagucgcggu ugucuuaucg ucgguaugcu      600

uauuaguaau aguaggcuua uuaauguucc gauaccaccg acgcgggggc uacgacguag      660

agaacgagga gaaggugaag cuagggauga cgaacucgca cugaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  5835
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt10)

<400>  5835
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggucacga aguuguuacc ggcguuauua uuacaacacg      120

uguuguuaca cuuguuguua uugccgauag cgauaccgua ugccgaaggg cagcgcaagc      180

gccgcaauac cauccacgag uuuaagaaga gugccaaaac cacguugaua aagaucgacc      240

cggccuuaaa aaucaagacg aaaaagguca acaccgccga ucagugcgcc aaccgcugca      300

cccgcaacaa gggguugccg uuuaccugua aagccuucgu cuucgacaag gcccgcaagc      360

aauguuugug guuuccguuu aacucgauga gcucgggggu caagaaggag uucgggcacg      420

aguucgauuu guaugagaau aaggauuaua uccgcaauug uauaaucggg aaagggaggu      480

cguauaaagg gaccgucagc auaaccaaau cggggauaaa augccaaccg uggucgagua      540

ugaucccgca ugagcauucg uuccucccga gcucguacag agggaaggau uugcaagaga      600

auuauugcag gaacccgagg ggcgaggagg gcgggccgug gugcuuuacc ucgaacccgg      660

aagucaggua ugaggugugc gauaucccgc aaugcagcga ggucgagugu augacgugua      720

acggcgaauc guacaggggg uugauggacc acaccgagag cgggaaaauc ugccaaaggu      780

gggaccacca aaccccgcau agacauaaau uucucccgga gcgcuauccg gauaaagggu      840

ucgacgacaa cuacuguagg aacccggacg ggcaaccccg cccguggugu uauaccuugg      900

auccgcauac gaggugggaa uauugcgcca ucaaaaccug ugccgauaac accaugaacg      960

auaccgacgu cccgcucgag accaccgagu guauacaggg gcagggggag ggguaucgcg     1020

ggaccgugaa cacgaucugg aacgggaucc cgugccaaag gugggacagc caauauccgc     1080

augaacacga uaugaccccg gagaacuuua aauguaaaga uuugagggag aacuauugua     1140

ggaacccgga cggcagcgag agcccguggu gcuucacgac cgacccgaau auaagggucg     1200

gguauuguag ucagaucccg aauugcgaca ugagccacgg gcaagacugc uauaggggca     1260

acgggaaaaa cuacaugggg aaucucaguc agacccgcag cggguugacc ugcagcaugu     1320

gggauaaaaa uauggaggau cuccacaggc acauauuuug ggagccggac gccucgaaau     1380

uaaacgaaaa cuauuguagg aacccggacg acgacgccca cgggccgugg uguuauaccg     1440

ggaacccguu gaucccgugg gacuauuguc cgaucaguag gugcgagggg gacacgaccc     1500

cgaccaucgu gaaccucgau cacccgguca ucagcugcgc gaagaccaag cagcucaggg     1560

ucgucaacgg caucccgacc aggaccaaua ucggguggau ggucucgcuc cgcuaucgca     1620

acaagcacau augugggggg agccucauca aagaaucgug ggucuugacc gccaggcaau     1680

gcuuuccgag cagggaucuc aaggacuacg aggccugguu ggggauccac gacgugcaug     1740

ggcgcgggga cgaaaagugu aagcaagucu ugaacgucag ucaauuaguc uacgggccgg     1800

aggggagcga cuuaguccuc augaaauugg cgcgcccggc cguguuagac gacuucgucu     1860

cgaccaucga ccucccgaau uacgggugua ccaucccgga gaaaacgucg uguucggucu     1920

augggugggg guauaccggg cucauaaauu acgacggguu gcucaggguc gcccacuugu     1980

auaucauggg gaacgaaaag uguucgcaac accacagggg caaagucacc uuaaacgaaa     2040

gcgagaucug cgccggcgcc gagaaaaucg ggagcgggcc gugcgaaggc gacuaugggg     2100

ggccguuggu cugcgaacag cacaaaaugc gcauggucuu gggggugauc gucccgggga     2160

gggggugcgc gaucccgaac aggccgggga ucuucgugag ggucgccuac uacgccaagu     2220

ggauccauaa gaucauccuc accuauaaag ucccgcaaag cugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  5836
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt10)

<400>  5836
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgaaggcgg cggcaauagg gauagacuua gguacgacgu      120

acucgugcgu ugguguauuc cagcacggua agguagagau aauagcgaac gaccagggua      180

accggacgac gccgaguuac gucgcguuca ccgacacgga gcgcuugauc ggggacgccg      240

cgaagaacca gguagcuuua aacccacaaa acacgguuuu cgacgcaaag cgacucauag      300

ggcgaaaguu cggggacccc gucguacaau cagacaugaa gcacuggccg uuccagguca      360

uaaacgacgg ugacaagccg aagguccagg uaaguuacaa gggcgagacg aaggcguucu      420

acccugagga gaucucaagu augguauuga cgaagaugaa ggagauagcg gaggcauacu      480

uaggauaccc cgugacgaac gccguaauca cgguccccgc guacuucaac gacucucagc      540

ggcaggcgac gaaggacgca ggcguaaucg caggguuaaa cguauugcgc aucauaaacg      600

agccgaccgc ggcggcgaua gcauacgggu uagaccggac cgggaagggu gagcgaaacg      660

uauuaaucuu cgacuugggu ggggguacgu ucgacgucuc gauauuaacc aucgacgacg      720

gcauauucga gguaaaggcg accgccgggg acacgcacuu aggcggggag gacuucgaca      780

accgauuggu caaccacuuc guagaggagu ucaagcgaaa gcacaagaag gacauaucgc      840

agaacaagcg ugcgguaaga agguuacgaa cggcgugcga gcgggcuaag cgcacguuaa      900

guucgaguac gcaggcgucg uuggagauag acaguuuauu cgaggguaua gacuucuaca      960

cuucgauaac gcgugcacga uucgaggagu uaugcucgga cuuauucagg ucgacguuag     1020

agccgguaga gaaggcauua cgagacgcga aguuggacaa ggcacagaua cacgacuuag     1080

uauuaguagg ugguucgacg cggauaccga agguacagaa guuguuacag gacuucuuca     1140

acggucgaga cuuaaacaag ucgaucaacc cggacgaggc gguagcguac ggggccgcgg     1200

uacaggccgc gauauugaug ggugacaaga gugagaacgu acaggacuua uuauuauuag     1260

acguagcacc cuuaucuuug gguuuagaga ccgcgggugg ggucaugacg gcguuaauaa     1320

agcgaaacuc gacgaucccg acgaagcaga cccagaucuu cacuacguac ucggacaacc     1380

agccgggugu auugauccag guauacgagg gugagcgagc gaugaccaag gacaacaacu     1440

uauuaggacg uuucgaguug ucggguauac cgcccgcacc ucgagggguc ccgcagaucg     1500

aggucacguu cgacaucgac gcgaacggua ucuuaaacgu aacggcgacc gacaaaagua     1560

cggggaaggc caacaagauc acgauaacga acgacaaggg ucgauuaucg aaggaggaga     1620

uagagaggau gguccaggag gcagagaagu acaaggccga ggacgagguc cagagagagc     1680

gaguaagugc gaagaacgcg uuggagucgu acgcguucaa caugaagagu gcggucgagg     1740

acgaggguuu aaaggguaag aucucggagg ccgacaagaa gaaggucuua gacaagugcc     1800

aggagguuau aucuugguua gacgcgaaca cguuagcgga gaaggacgag uucgagcaca     1860

agcgcaagga guuagagcag guaugcaacc cgauaauauc ggguuuguac cagggggcgg     1920

gcgggccggg uccggguggu uucggcgcgc agggaccgaa gggugguagu gggucggguc     1980

cgacgaucga ggagguagac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  5837
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt10)

<400>  5837
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgaaggcgg cggcaauagg gauagacuua gguacgacgu      120

acucgugcgu ugguguauuc cagcacggua agguagagau aauagcgaac gaccagggua      180

accggacgac gccgaguuac gucgcguuca ccgacacgga gcgcuugauc ggggacgccg      240

cgaagaacca gguagcuuua aacccacaaa acacgguuuu cgacgcaaag cgacucauag      300

ggcgaaaguu cggggacccc gucguacaau cagacaugaa gcacuggccg uuccagguca      360

uaaacgacgg ugacaagccg aagguccagg uaaguuacaa gggcgagacg aaggcguucu      420

acccugagga gaucucaagu augguauuga cgaagaugaa ggagauagcg gaggcauacu      480

uaggauaccc cgugacgaac gccguaauca cgguccccgc guacuucaac gacucucagc      540

ggcaggcgac gaaggacgca ggcguaaucg caggguuaaa cguauugcgc aucauaaacg      600

agccgaccgc ggcggcgaua gcauacgggu uagaccggac cgggaagggu gagcgaaacg      660

uauuaaucuu cgacuugggu ggggguacgu ucgacgucuc gauauuaacc aucgacgacg      720

gcauauucga gguaaaggcg accgccgggg acacgcacuu aggcggggag gacuucgaca      780

accgauuggu caaccacuuc guagaggagu ucaagcgaaa gcacaagaag gacauaucgc      840

agaacaagcg ugcgguaaga agguuacgaa cggcgugcga gcgggcuaag cgcacguuaa      900

guucgaguac gcaggcgucg uuggagauag acaguuuauu cgaggguaua gacuucuaca      960

cuucgauaac gcgugcacga uucgaggagu uaugcucgga cuuauucagg ucgacguuag     1020

agccgguaga gaaggcauua cgagacgcga aguuggacaa ggcacagaua cacgacuuag     1080

uauuaguagg ugguucgacg cggauaccga agguacagaa guuguuacag gacuucuuca     1140

acggucgaga cuuaaacaag ucgaucaacc cggacgaggc gguagcguac ggggccgcgg     1200

uacaggccgc gauauugaug ggugacaaga gugagaacgu acaggacuua uuauuauuag     1260

acguagcacc cuuaucuuug gguuuagaga ccgcgggugg ggucaugacg gcguuaauaa     1320

agcgaaacuc gacgaucccg acgaagcaga cccagaucuu cacuacguac ucggacaacc     1380

agccgggugu auugauccag guauacgagg gugagcgagc gaugaccaag gacaacaacu     1440

uauuaggacg uuucgaguug ucggguauac cgcccgcacc ucgagggguc ccgcagaucg     1500

aggucacguu cgacaucgac gcgaacggua ucuuaaacgu aacggcgacc gacaaaagua     1560

cggggaaggc caacaagauc acgauaacga acgacaaggg ucgauuaucg aaggaggaga     1620

uagagaggau gguccaggag gcagagaagu acaaggccga ggacgagguc cagagagagc     1680

gaguaagugc gaagaacgcg uuggagucgu acgcguucaa caugaagagu gcggucgagg     1740

acgaggguuu aaaggguaag aucucggagg ccgacaagaa gaaggucuua gacaagugcc     1800

aggagguuau aucuugguua gacgcgaaca cguuagcgga gaaggacgag uucgagcaca     1860

agcgcaagga guuagagcag guaugcaacc cgauaauauc ggguuuguac cagggggcgg     1920

gcgggccggg uccggguggu uucggcgcgc agggaccgaa gggugguagu gggucggguc     1980

cgacgaucga ggagguagac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  5838
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt10)

<400>  5838
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgacggcga aggguauagc uauagguaua gacuuaggaa      120

cgacauacuc gugcguaggu gucuuccagc acgggaaggu cgagaucaua gcuaacgacc      180

aggggaacag gacaacgccg aguuacgucg cguucaccga cacugagaga uugaucggug      240

acgcggcgaa gaaccagguc gcgaugaacc cucaaaacac gguauucgac gcgaagcggu      300

uaaucggucg caaguucaac gacccggucg uucaggcgga caugaaguua uggccguucc      360

aaguaauaaa cgagggcgga aagccgaagg uauugguauc guacaagggu gagaacaagg      420

cauucuaccc ggaagagaua aguucgaugg uuuuaaccaa guuaaaggag acagcggagg      480

cguucuuagg ucauccggua acuaacgcgg uaaucacggu acccgcuuac uucaacgaca      540

gucagcggca ggcgacgaag gacgcggggg ucauagcggg uuuaaacgua uuacgcauaa      600

uaaacgagcc aacggcagcg gcgauagcgu acggucuuga caagggggga cagggugagc      660

ggcacguauu aaucuucgac uuagguggcg guacauucga cgucucgaua uugacgaucg      720

acgacgguau auucgaggua aaggcgacgg cgggugacac gcacuuaggu ggugaggacu      780

ucgacaacag auuaguaagu cacuucgucg aggaguucaa gcggaagcac aagaaggaca      840

uaucgcaaaa caagcgcgcu guaaggagau ugcggacggc cugcgagcgc gcgaagcgga      900

cguuaaguuc gucgacgcag gcgaaccucg agauagacuc guuguacgag gguauagacu      960

uuuacacgag uaucacgcga gcgagauucg aggaguuaug cgccgacuua uuccgcggga     1020

cauuggagcc cguugagaag gcguuaaggg acgcgaagau ggacaaggcg aagauccacg     1080

acauaguauu agucgguggu ucgacccgaa uaccgaaggu acagcgguua uuacaagacu     1140

acuucaacgg ucgcgacuug aacaagucga uaaacccgga cgaggcggua gcguacgggg     1200

cggcagucca ggcggcgaua uuaauggggg acaagucgga gaagguccaa gacuuauuau     1260

uguuggacgu ugcgccguua aguuuagguu uagagacugc gggcggugua augacggcgu     1320

uaaucaagcg gaacucgaca auaccaacga agcagacgca aauauucacu acguacagug     1380

acaaccagcc ggguguauug auacagguau acgaggguga gcgggcgaug acgaaggaca     1440

acaacuuauu aggucguuuc gacuuaacug guauaccucc ggcuccgcgg gggguaccgc     1500

aaauagaggu cacguucgac auagacgcga acgggaucuu aaacguaacg gcgaccgaca     1560

agucgacagg uaagguuaac aagauaacua uaacgaacga caaggguaga uuaucgaagg     1620

aggagaucga gaggaugguc uuggacgcgg agaaguacaa ggcagaggac gagguacaga     1680

gagaaaagau agcggcgaag aacgcguuag agaguuacgc guucaacaug aagucgguag     1740

uaucggacga gggauuaaag gguaagaucu cggagaguga caagaacaag auauuagaca     1800

agugcaacga guuauuaucg ugguuggagg uuaaccaguu agcggagaag gacgaguucg     1860

accauaagag gaaggaguua gagcaaaugu gcaacccgau caucacgaag uuauaccagg     1920

gggguugcac ggguccggcg ugcgguacgg guuacguccc ugggcgaccg gcaacagguc     1980

cgacgauaga ggagguagac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  5839
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt10)

<400>  5839
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucggccaggg ggccggccau agggaucgau uuggggacga      120

cguauagcug ugucgggguc uuucaacaug ggaaggugga gaucauagcc aaugaucagg      180

gcaaucgcac gaccccgagu uacgucgcgu ucaccgauac ggagagguug auaggggaug      240

ccgcgaaaaa ucaagucgcc augaauccga ccaauaccau auuugaugcc aaacgcuuga      300

uagggaggaa auuugaggau gccaccgugc agucggauau gaaacauugg ccguuuaggg      360

ucgucaguga gggggggaag ccgaaaguac agguggagua uaagggggaa accaaaacgu      420

ucuuuccgga ggaaauaagc ucgauggucu ugacgaagau gaaggagauc gccgaagccu      480

acuugggggg gaaagugcau ucggccguca ucaccgugcc ggccuauuuc aaugauucgc      540

agcgccaggc caccaaggau gccgggacga ucaccggguu gaauguguug aggaucauaa      600

acgagccgac cgccgccgcc auagccuaug gguuggauaa aaaggggugu gcgggggggg      660

aaaagaaugu guugaucuuu gauuuggggg gcgggaccuu ugaugugagc aucuugacga      720

ucgaggaugg gauauuugaa gugaagucga ccgcggggga uacccauuug gggggcgagg      780

auuuugauaa uaggaugguc ucgcacuugg cggaggaauu uaagcgcaaa cauaaaaagg      840

acaucgggcc gaauaagaga gccguccgcc gcuugcgcac ggccugugag agagccaagc      900

gcacguuguc gagcucgacc caggccucga ucgagauaga uaguuuguau gagggcgucg      960

auuuuuauac gagcauaacc agagcgaggu ucgaagaguu gaaugcggac uuauuuaggg     1020

ggaccuugga gccgguggag aaggccuuga gggaugccaa gcucgauaag gggcagaucc     1080

aggagaucgu guuagugggg gggaguacga ggauaccgaa gauacagaag uuguugcagg     1140

auuuuuuuaa uggcaaggag uugaauaaga gcaucaaucc ggacgaggcc guggcguaug     1200

gggccgccgu ccaggccgcc aucuugauag gcgauaaguc ggaaaaugug caggauuugu     1260

uguuauugga ugucacgccg uugagcuugg gcaucgaaac cgccgggggg gucaugacgc     1320

cguuaaucaa gaggaauacc acgaucccga ccaagcaaac gcaaacguuu accacguauu     1380

cggauaauca aagcaguguc uuggugcaag ucuaugaagg ggagagggcc augaccaagg     1440

auaauaauuu gcucgggaaa uuugauuuga ccgggauccc cccggccccg aggggggucc     1500

cgcagauaga ggugaccuuc gauaucgaug cgaaugggau auugaauguc acggccgcgg     1560

auaagucgac cggcaaagag aauaaaauaa ccaucaccaa ugauaagggc cgcuuaucga     1620

aggaugauau cgauaggaug gugcaggagg ccgagaggua uaagagcgag gacgaagcca     1680

aucgcgauag gguggccgcc aaaaaugccu uagagagcua uacguauaau auaaaacaaa     1740

cgguggagga ugagaaguua agggggaaga ucucggagca ggauaagaau aagaucuuag     1800

auaagugcca ggaggugauc aauugguugg auaggaauca gauggcggag aaggaugagu     1860

augagcauaa gcagaaggag uuggagaggg ucuguaaucc gaucauaagc aagcucuauc     1920

agggggggcc gggggggggc ucgggggggg gggggagugg ggccucgggg gggccgacga     1980

uagaggaggu cgacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  5840
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt10)

<400>  5840
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucagucguag guaucgaccu cgguuuucaa aguuguuacg      120

uagcgguagc gcgagcugga gguauagaga cgauagcaaa cgaauacucg gaccgaugca      180

cuccugcgug cauaucguuc gggccgaaga acaggucgau aggggccgcg gcaaagucgc      240

agguuaucuc aaacgcgaaa aacacgguac aggguuucaa gcgauuucac ggucgugcgu      300

ucucggaccc uuucgucgag gccgagaaga guaacuuagc guacgacaua guucaauuac      360

cgacgggucu cacgggcauu aagguaacuu acauggaaga ggagcgcaac uucacuacgg      420

agcagguaac ggcgauguug uuaucgaagu uaaaggaaac ggcagagucg guauuaaaga      480

agccaguggu agacugcgua guaucaguac cgugcuucua cacggacgcg gagcggcguu      540

cgguuaugga cgccacgcag auagcggggc ucaacuguuu acgccuaaug aacgagacga      600

cggccguagc guuagcguac gggauuuaca agcaggacuu gccagcgcuu gaggagaagc      660

cgcgcaacgu uguauucgug gacaugggac acucggcaua ccaggugucg gucugcgcgu      720

ucaaccgggg gaagcucaag gucuuagcga cggcguucga caccacguua ggcggacgca      780

aguucgacga gguacucguu aaccacuucu gcgaggaguu cgguaagaag uauaaguuag      840

acauaaaguc gaagauucga gcguugcuuc guuuaucgca ggagugcgag aaguuaaaga      900

aguuaauguc agcgaacgcg ucggacuugc cccuuucgau cgagugcuuc augaacgacg      960

uagacguuuc agggaccaug aacaggggga aguucuuaga gauguguaac gacuuauugg     1020

cacgagucga accucccuug aggucggucu uagagcagac aaaguugaag aaggaggaca     1080

uauacgcggu agagaucguc ggaggggcaa cgcguauucc ggcaguuaag gagaagauau     1140

cgaaguucuu cggcaaggag uuaucgacga cgcuuaacgc ggacgaggcg guaacgaggg     1200

guugcgcguu acagugcgcu auacuuucuc cagcguucaa gguacgcgag uucucgauaa     1260

cggacguugu uccguacccc aucaguuuac gguggaacuc gccggcggag gaggguucgu     1320

cggacugcga gguguucucg aagaaccacg cggcgcccuu cucgaagguc uuaacguucu     1380

accgaaaaga gccguucaca uuagaggcau acuacaguuc gccacaggac cuuccuuacc     1440

cggacccggc gaucgcacag uucucgguac aaaagguuac gccccagucg gacgguucgu     1500

cgucgaaggu caagguaaag gugaggguua acguucacgg uaucuuuucg gucaguucgg     1560

cgucgcuugu agagguccac aagucggagg agaacgagga gccgauggag acggaccaga     1620

acgcgaaaga ggaggagaaa augcagguag accaggagga gccgcacgua gaggagcagc     1680

aacagcagac gccggcggag aacaaggcgg agucggagga gauggagacu ucgcaggcgg     1740

gcucgaagga caagaaaaug gaccagccuc cgcaggcgaa aaaggcgaag gucaagacau     1800

cuaccgucga cuuaccgaua gagaaccagu uauuguggca aaucgaccga gagauguuaa     1860

acuuauacau cgagaacgag gggaaaauga ucaugcagga caaguuggaa aaggagcgca     1920

acgacgcgaa aaacgcgguu gaggaguacg uuuacgagau gcgugacaag uuaucgggcg     1980

aguacgagaa guucgucucg gaggacgacc gaaacucauu cacguuaaag uuggaggaca     2040

cggagaacug guuauacgag gacggggagg accaaccgaa gcagguauac gucgacaagc     2100

uagcggagcu uaagaacuug ggacagccca uaaagaucag guuccaagag agugaggagc     2160

gcccgaagcu auucgaggag uuagguaagc aaauacagca guacaugaag aucauaucua     2220

guuuuaagaa caaggaggac caauacgacc acuuagacgc ggcagacaug acuaaggucg     2280

agaagaguac gaacgaggcg auggagugga ugaacaauaa guuaaacuua caaaacaagc     2340

agucguuaac gauggacccg guaguaaagu cgaaggagau cgaggccaag aucaaggagu     2400

uaaccucuac augcucgcca aucauaucga agccgaagcc gaagguagag ccgccgaagg     2460

aggagcagaa gaacgccgag caaaacggcc ccguagacgg ucagggugac aaccccgggc     2520

cucaggcggc agaacagggg acggacaccg cgguaccguc ugacucggac aaaaaguuac     2580

cggagaugga caucgacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  5841
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt10)

<400>  5841
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgucgucg ggaucgauuu gggguucuug aauuguuaua      120

uagccguggc ccgcucgggg gggauagaaa cgauagcgaa cgaauauucg gaucgcugua      180

cgcccgcgug caucagccuc gggagccgca ccagggcgau agggaacgcc gccaaaucgc      240

aaaucgugac caauguccgc aacaccaucc acggguuuaa gaaauugcac ggcaggagcu      300

ucgacgaucc gaucguccag accgagcgca uacgcuugcc guacgaauua caaaagaugc      360

cgaacggguc ggccgggguc aaagucagau aucucgaaga ggaacgcccg uucgccaucg      420

aacaagucac cgggauguua cucgcgaaau ugaaggaaac cagcgagaac gcccucaaaa      480

agccggucgc cgauugcguc aucagcaucc cgucguuuuu caccgacgcg gaacgccgca      540

gcgucauggc cgccgcgcaa gucgccgggc ucaacugccu ccgccucaug aacgagacca      600

ccgccgucgc cuuagccuac gggaucuaca agcaagacuu gccgccgcuc gacgaaaagc      660

cgcgcaacgu cgucuucauc gacauggggc auagcgcgua ccaagugcuc gucugcgccu      720

uuaauaaagg gaaguugaag gugcucgcca ccacguucga cccguaccuc ggggggcgca      780

auuucgacga agcccucguc gauuauuuuu gcgacgaauu uaaaacgaag uacaaaauca      840

acgucaagga gaauagcaga gcgcuccuca ggcucuacca agaaugcgag aaguugaaaa      900

aauugauguc ggccaacgcc agcgacuugc cgcucaauau cgaaugcuuu augaacgauu      960

uggacgucag cucgaagaug aaucgcgccc aguucgaaca auuaugcgcc aguuugcucg     1020

cgcgcgucga gccgccgcuc aaagccguca uggagcaagc caaucuccaa agggaggaua     1080

ucucgucgau cgagaucguc gggggggcca ccaggauccc ggccgucaag gagcaaauaa     1140

ccaaguuuuu cuugaaggau aucucgacga cccucaacgc cgacgaggcc gucgcccgcg     1200

ggugcgcccu ccaaugcgcc aucuugagcc cggccuucaa ggucagggag uucaguauca     1260

ccgauuuggu cccguacagc auaacccucc gcuggaaaac gagcuucgag gacgggucgg     1320

gcgagugcga ggucuuuugc aaaaaucauc cggcgccguu uagcaaagug aucaccuuuc     1380

auaaaaaaga gccguucgag uuggaggccu ucuacaccaa ccuccaugag gucccguauc     1440

cggacgcccg caucggcucg uuuaccaucc aaaacgucuu cccgcaaagc gacggggacu     1500

cgaguaaggu caaagucaag gucaggguca auauacacgg gauauuuucg gucgccucgg     1560

ccagcgucau cgaaaaacag aaccucgagg gggaccauuc ggacgccccg auggaaaccg     1620

agaccagcuu caagaacgag aauaaggaca acauggacaa gaugcaaguc gaccaagagg     1680

agggccacca gaagugccac gccgagcaua ccccggagga agagaucgac cauaccgggg     1740

cgaagaccaa aagcgccgug agcgauaagc aagauaggcu caaccaaacc uugaagaagg     1800

ggaaaguaaa gucgaucgac uugcccauac aaucgucguu gugccgccaa uuggggcaag     1860

acuuguuaaa uucguauauc gagaacgaag gcaaaaugau aaugcaagac aaacucgaaa     1920

aggagcgcaa cgacgccaaa aacgcggucg aggaguacgu cuacgacuuc cgcgaucgcu     1980

uagggaccgu guacgagaag uuuauaaccc cggaagaucu cucgaaauua agcgccgucc     2040

ucgaggauac cgaaaacugg uuguacgagg auggggaaga ucaaccgaag caggucuacg     2100

ucgacaaauu gcaggaguug aaaaaguaug ggcaaccgau ccaaaugaaa uauauggaac     2160

acgaagaacg cccgaaggcg cucaacgauc ucgggaaaaa aauacaauug gugaugaaag     2220

ucaucgaagc cuaccgcaau aaagacgagc gcuacgacca cuuagacccg accgaaaugg     2280

agaaagucga gaagugcaua ucggacgcga ugucgugguu aaacucgaaa augaacgccc     2340

aaaauaaguu gucguugacc caggacccgg ucgucaaggu cagcgagauc gucgccaaaa     2400

gcaaagaguu agacaacuuu ugcaauccga uaaucuauaa accgaaaccg aaggccgagg     2460

ucccggagga uaagccgaag gccaacucgg aacauaacgg gccgauggac gggcaaucgg     2520

ggaccgagac caagagcgac agcaccaagg auucgagcca acacaccaaa aguagcgggg     2580

aaauggaggu cgauugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  5842
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt10)

<400>  5842
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauugaguu uagucgcggc cauguuauua uuauugucgg      120

ccgccagagc ggaagaagaa gauaaaaaag aagaugucgg gaccgucgug gggauagauu      180

uaggcacgac guauaguugu gugggggucu uuaaaaaugg gagggucgaa auaauagcga      240

augaccaagg gaauaggaua acccccaguu acguggcguu uaccccggag ggcgagaggu      300

uaaucgggga cgcggcgaaa aaucaauuga cgaguaaucc ggaaaauacc guguucgaug      360

cgaaaagauu gauagggagg accuggaacg aucccagcgu ccaacaagau auaaaauuuc      420

uccccuuuaa agucgucgag aaaaagacca agccguauau ccaggucgac aucggggggg      480

gccagaccaa aaccuucgcc ccggaggaga ucagcgcgau ggucuugacc aagaugaagg      540

agacggccga agccuaccuc gggaaaaaag ucacgcacgc cgucgucacc gucccggcgu      600

acuucaacga cgcgcagagg caggccacga aggaugccgg gaccaucgcc ggguugaacg      660

ucaugcgcau aauaaaugaa ccgaccgccg ccgccaucgc cuacggguua gacaaacgcg      720

aaggcgaaaa aaauauauua gucuucgauu uagggggggg gacguuugac gucagcuugu      780

ugacgaucga uaacggggug uuugaggucg ucgcgaccaa cggggacacc cacuuagggg      840

gggaggauuu cgaucaaagg gugauggagc auuuuauaaa guuauauaag aaaaaaaccg      900

ggaaggacgu gcgcaaggau aaccgcgccg uccaaaaguu gagaagggaa gucgagaaag      960

cgaagagagc guuaagcagc caacaccagg cccgcaucga gaucgaaagu uuuuacgagg     1020

gggaggauuu cagcgaaacg uuaaccagag cgaaguucga ggaauugaau auggacuuau     1080

uuagaagcac caugaaaccg gugcaaaagg uccucgagga cagcgaccuc aaaaaaagcg     1140

acaucgacga gaucgucuug gucgggggga gcaccaggau cccgaaaauc caacaguuag     1200

ucaaggaauu uuuuaacggg aaagagccga guagggggau caauccggac gaggccgucg     1260

ccuacggggc cgccgugcaa gccggggucu ugagcgggga ccaggacacc ggggauuuag     1320

ucuuauugga cgucugcccg uugaccuugg ggaucgagac cgucgggggg gugaugacga     1380

aguuaauccc gcgcaauacc gucgucccga cgaaaaaaag ccaaauauuc agcaccgcca     1440

gcgacaacca gccgaccguc accauaaaag uguacgaggg ggagcgcccg uuaaccaagg     1500

auaaccacuu guuagggacc uucgacuuaa ccgggauccc gccggccccg aggggcgugc     1560

cgcaaaucga ggugacguuc gaaaucgacg ucaacgggau cuugaggguc accgccgagg     1620

auaaagggac cggcaauaag aacaaaauaa ccauaacgaa cgaucaaaac agguuaaccc     1680

cggaggagau agagcgcaug gucaacgacg ccgaaaaauu cgccgaagag gauaagaaau     1740

ugaaagaaag gaucgacacc cgcaacgaac ucgagucgua cgcguacagc uugaaaaacc     1800

aaaucgggga caaggagaaa uuagggggga aguugaguag cgaggacaaa gaaacgaugg     1860

agaaggccgu cgaggagaaa aucgaguggu uagagucgca ucaggacgcc gauaucgagg     1920

auuuuaaggc caaaaaaaaa gaguuagagg agaucgucca gccgaucaua ucgaaguugu     1980

acgggucggc cgggccgccg ccgaccgggg aggaagacac cgccgagaag gacgaacucu     2040

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  5843
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt10)

<400>  5843
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcgccga gagaauuggc cgucgggaua gauuuaggga      120

cgacguauag cugugucggg gucuuccaac aagggagggu cgaaauauua gcgaaugauc      180

aagggaauag gacgaccccg ucguaugucg cguuuacgga uacggaaaga uuagugggcg      240

augccgcgaa aucgcaagcc gcguuaaauc cgcauaauac ggucuuugac gcgaaaagau      300

uaauaggcag gaaauuugcc gauacgaccg uccaaagcga uaugaaacau uggccguuua      360

gagucgucuc ggaagggggg aaaccgaaag ucagggucug uuauaggggc gaagauaaaa      420

ccuuuuaucc ggaagaaaua agcaguaugg ucuuaucgaa aaugaaagaa accgcggaag      480

ccuauuuagg gcaaccgguc aaacaugccg ucauaacggu cccggcguac uuuaacgaua      540

gccaaaggca agcgacgaaa gaugccggcg cgauagccgg cuugaauguc cucagaauaa      600

uaaacgaacc gaccgccgcc gcgauagcgu acggcuuaga uagaagaggg gccggggaaa      660

ggaaugucuu gaucuucgau uuagggggcg ggacguuuga cgucagcguc uugaguaucg      720

augccggggu guucgaaguc aaggcgaccg ccggggacac gcauuuaggg ggggaagauu      780

uugauaauag auuggucaau cauuuuaugg aggaguuuag aagaaaacac ggcaaagauu      840

uaucgggcaa uaaaagggcg uuaaggcgcu uaaggaccgc gugcgaaagg gcgaaaagga      900

cguuaaguag uucgacgcaa gcgacguuag aaaucgauag uuuauuugaa ggggucgauu      960

uuuauaccag uauaaccagg gcgagguucg aagaguuaug uagcgauuug uuuaggucga     1020

cguuagaacc cgucgaaaaa gcguuaagag acgcgaaauu agauaaagcg caaauccacg     1080

augugguguu agucggcggg aguaccagga uaccgaaagu ccaaaaacuc uuacaagauu     1140

uuuuuaaugg gaaagaauua aauaaaucga uaaauccgga cgaagccguc gcguacggcg     1200

ccgccgucca agccgcgguc cucaugggcg auaagugcga aaagguccaa gacuuguuau     1260

uauuagacgu cgccccgcuc agcuuaggcu uagaaaccgc cgggggcguc augacgaccu     1320

uaauacaacg caaugcgacc auaccgacga aacaaacgca aaccuuuacg acguauagcg     1380

auaaucaacc gggcguguuu auacaagucu acgaagggga acgcgcgaug acgaaagaua     1440

auaauuuauu aggcagguuc gaguugucgg ggauaccgcc ggcgccgagg ggggugccgc     1500

aaaucgaagu caccuucgau aucgacgcca acgggauauu aucggucacc gcgaccgauc     1560

gcucgaccgg gaaagccaau aaaauaacga uaacgaacga uaaagggaga uuaucgaaag     1620

aagaagucga acgcaugguc cacgaggcgg aacaauauaa agccgaagac gaagcgcaac     1680

gcgaucgcgu cgccgcgaag aauagcuuag aagcgcacgu guuucacguc aaggggagcc     1740

uccaggaaga gucguugcgc gauaaaaucc cggaggaaga ucgcaggaag augcaggaua     1800

aaugcagaga gguguuggcg ugguuagaac auaaucaauu agccgaaaaa gaagaauacg     1860

aacaccaaaa acgcgaauua gaacagauau gcaggccgau auuuagucgc uuguacggcg     1920

gcccgggggu gccgggcggg ucgucgugcg ggacccaggc gaggcaaggc gauccgucga     1980

cggggccgau aaucgaagaa gucgacugag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  5844
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt10)

<400>  5844
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggcgcccc gcgagcuggc cgugggcauc gaccucggga      120

ccaccuacag cugcgucggc guguuccagc aggggcgggu ggagauccug gccaacgacc      180

agggcaaccg cacgaccccg uccuacgucg ccuucaccga caccgagcgg cugguggggg      240

acgccgccaa gucgcaggcc gcgcucaacc cccacaacac gguguucgac gccaagcgcu      300

uaaucggccg gaaguucgcc gacaccaccg uccagagcga caugaagcac uggcccuucc      360

aggugguguc ggagggcggg aagcccaagg ucagggugug cuaccggggc gaggacaaga      420

ccuucuaccc ggaggagauc agcagcaugg uguuauccaa gaugaaggag acggccgagg      480

cguaccucgg gcagcccguc aagcacgccg ugaucaccgu gcccaccuac uucucgaaca      540

gccagaggca ggccaccaag gacgccggcg ccaucgcggg gcugaagguc uuacccauca      600

ucaacgaggc cacggccgcc gccaucgcgu acggccucga cagacgcggc gccgggaagc      660

ggaacgugcu gaucuucgac uuaggcgggg gcaccuucga cgugagcguc uugaguaucg      720

acgccggcgu guucgaggug aaggccaccg ccggggacac ccacuuaggc ggggaggacu      780

ucgacaaccg ccuggucaac cacuucaugg aggaguucag acgcaagcac ggcaaggacc      840

ucucggggaa caagcgggcg uuaaggcggu uaaggacggc cugcgagcgg gccaagagga      900

ccccgaguag cuccacccag gccacccucg agaucgacag cuuauucgag ggcguggacu      960

ucuacaagag uaucacgcgg gccagguucg aggaguuaug cagcgacuug uucaggucca     1020

ccuuagagcc cguggagaag gcguuaagag acgccaagcu cgacaaggcc cagauccacg     1080

acuucgucuu aggcgggggc cugcacagcc acccccaggg ggccgaggug gcggccggcc     1140

uccugcagcg ccagggggcc gagcaggagc accagcccug aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  5845
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt10)

<400>  5845
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucgaaggggc cggcgguagg uauagacuua ggcacgacgu      120

acucgugcgu agggguauuc cagcacggca agguagagau caucgcgaac gaccagggga      180

accgaacaac gccgucguac guagcauuca ccgacacgga gcgcuuaaua ggcgacgcgg      240

cgaagaacca gguagcgaug aacccgacua acacggucuu cgacgcgaag cgguuaaucg      300

gucgacgguu cgacgacgcg guaguacagu cggacaugaa gcacuggccc uucauggucg      360

uuaacgacgc agguagaccg aagguacagg uggaguacaa gggcgagacc aagucguucu      420

acccggagga ggucucgucg augguguuaa ccaagaugaa ggagaucgcg gaggcguacu      480

uggguaagac ggugacgaac gcagucguua cggucccggc guacuucaac gacagucagc      540

gacaggcgac uaaggacgcg gguacgaucg cgggauuaaa cgucuuacga aucaucaacg      600

agccgacggc ggccgcgaua gcguacgggc uagacaagaa gguaggugcg gagaggaacg      660

uauuaaucuu cgacuugggg ggcgggacgu ucgacguauc gauauuaacc aucgaggacg      720

guauuuucga gguaaagagu accgcagggg acacccacuu agggggggag gacuucgaca      780

accguauggu aaaccacuuc auagcggagu ucaagcggaa gcacaagaag gacauaucgg      840

agaacaagcg cgccguacga cguuuacgga cggcgugcga gagagcgaag cgaaccuuaa      900

guucgaguac ucaggcaucg auagagauag acucguuaua cgaggggauc gacuucuaca      960

cgucgaucac gcgagcgcgg uucgaggagu ugaacgccga cuuguuccga gggacgcuug     1020

acccggugga gaaggcguua cgggacgcua aguuagacaa gagucagaua cacgacauag     1080

uauuaguagg ggggucgacg cgaaucccua agauacagaa guuauugcag gacuucuuca     1140

acggcaagga guuaaacaag aguauaaacc cggacgaggc aguagccuac ggggcggcgg     1200

uacaggcggc gauucucucg ggugacaagu cggagaacgu gcaggacuua uuauuauuag     1260

acguaacgcc cuuaucgcuc gggaucgaga cggcgggggg gguaaugacg guauugauca     1320

agaggaacac gacgauaccg acgaagcaaa cgcagacguu cacgaccuac ucggacaacc     1380

agccgggcgu auuaauacag guauacgagg gcgagcgggc caugacgaag gacaacaacc     1440

uuuuagguaa guucgaguua acggguauuc cgccggcgcc gaggggggua ccgcaaaucg     1500

agguaacguu cgacauagac gcgaacggga uccuuaacgu aagugcggua gacaagucga     1560

cggguaagga gaacaagauc acgauaacga acgacaaggg ccgcuuaagu aaggaggaca     1620

ucgagcgcau gguacaggag gcggagaagu acaaggcgga ggacgagaag cagcgagaca     1680

agguaucguc gaagaacucg uuggagaguu acgcguucaa caugaaggcg acgguagagg     1740

acgagaaguu acaggguaag aucaacgacg aggacaagca gaagaucuug gacaagugca     1800

acgagauaau caacugguua gacaagaacc agacggcgga gaaggaggag uucgagcacc     1860

agcaaaagga guuagagaag guaugcaacc cgaucauaac gaagcuauac caguccgcgg     1920

gugggaugcc gggggggaug ccgggcgguu uccccggagg gggugccccg ccgagugggg     1980

gggcgucguc gggcccgacg aucgaggagg ucgacugagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  5846
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt10)

<400>  5846
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucucggcgu cgagggccgc cgccgcgagg uuggucgggg      120

cggccgcgag uagagggccg accgcggcga ggcaucaaga cucguggaac ggguugucgc      180

acgaagccuu ccgcuugguc agccgcagag acuacgccag cgaggcgaua aaaggggccg      240

ucgucgggau cgaucucggg accacgaaua guugugucgc cgucauggag gggaagcaag      300

cgaaagucuu agaaaacgcg gagggggcgc gcacgacgcc gagcgucguc gcguucaccg      360

ccgacgggga aagguugguc gggaugcccg cgaaaaggca agccgugacg aauccgaaua      420

auaccuucua cgccacgaaa agguugaucg ggagaaggua cgacgacccg gagguccaaa      480

aggauaucaa gaacgucccg uuuaagaucg ugagggcgag uaacggggac gcgugggucg      540

aagcccaugg caagcucuac agccccucgc aaauaggggc cuucguccuc augaaaauga      600

aggaaaccgc cgagaacuau cucggccaua ccgccaagaa cgccgucaua accgugccgg      660

ccuacuuuaa cgauagccaa cgccaagcga ccaaagacgc cgggcaaauu agcggguuaa      720

acgucuugag agucaucaac gaaccgaccg ccgccgccuu ggcguacggg uuggauaaga      780

gcgaggauaa gguaaucgcc gucuacgacc ucgggggggg gaccuucgac aucagcauau      840

uagagaucca aaaggggguc uucgaaguca agaguaccaa cggcgacacg uuucucgggg      900

gcgaggauuu cgaucaagcg cucuugagac auaucgucaa agaauuuaaa cgcgaaaccg      960

gcgucgaccu caccaaagau aauauggccu ugcaacgcgu cagagaggcc gccgagaaag     1020

ccaagugcga guugaguagc agcguccaaa ccgauauaaa ccucccguac uugaccaugg     1080

acagcagcgg gccgaaacac cucaacauga aacucacgag ggcccaguuc gagggcaucg     1140

ugaccgacuu gauacgccgc accauagccc cgugucaaaa ggccaugcag gacgccgagg     1200

uaucgaaauc ggauaucggg gaggucauau uggucggggg gaugacccgc augccgaaag     1260

uccaacaaac cguccaagau uuguucgggc gcgcgccguc gaaagccgug aacccggacg     1320

aagccgucgc gaucggggcc gcgauccaag gggggguccu cgcgggggac gugaccgacg     1380

ucuuauuguu ggacgugacc ccgcucagcu uagggaucga gaccuugggg gggguguuca     1440

cgaaguugau caaccgcaac acgaccaucc cgacgaaaaa aucgcaaguc uuuagcaccg     1500

cggccgacgg gcagacccag gucgagauca aggucuguca aggggagcgc gaaauggccg     1560

gggauaauaa guuguugggg caauucaccc ucaucgggau cccgccggcg ccgagggggg     1620

ucccgcaaau cgaggucacc uucgauaucg acgcgaacgg caucguccac gucagcgcca     1680

aggacaaggg gaccgggagg gaacaacaaa ucgucauaca aagcagcggg gggcucucga     1740

aggacgacau cgagaacaug gucaaaaacg ccgaaaaaua cgccgaggag gauagaagga     1800

aaaaagagag ggucgaggcg gucaauaugg ccgaggggau aauccaugau accgaaacga     1860

aaauggaaga guuuaaagau cagcucccgg ccgacgaaug uaauaaauua aaggaggaaa     1920

ucaguaagau gcgcgaauug uuagcccgca aagauucgga aaccggggag aacauccgcc     1980

aagccgcgag uagcuugcaa caagccagcu uaaaauuauu ugagauggcc uauaaaaaaa     2040

uggccagcga aagggagggg agcgggucga gcgggaccgg cgagcaaaaa gaggaccaga     2100

aagaagagaa acaaugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  5847
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt10)

<400>  5847
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagacaagg aagcaggggg uucggacggc ccucgugaga      120

cugcaccuac uucggcguac ucuucgccgg cucgaucguu aggugacacu gggaucacgc      180

cguuaagucc gucgcacaua guaaacgaua cggacaguaa cguaucggag cagcagucgu      240

ucuuaguagu aguagcggug gacuucggua ccacgucguc ggguuacgcg uacucguuca      300

cgaaagagcc ggagugcaua cacgucaugc ggagguggga ggggggagac ccgggcguaa      360

guaaccagaa gacaccuacg acgauauuau uaacgccgga gcggaaguuc cacucguucg      420

guuacgcggc ccgugacuuc uaccacgacu uagacccaaa cgaggcaaag caaugguuau      480

acuuggagaa auucaaaaug aaguuacaca cuacgggaga cuuaacgaug gacacugacu      540

ugacugccgc gaacgguaaa aagguaaagg cgcucgagau cuucgcguac gcauuacagu      600

acuucaagga gcaggccuua aaggagcucu cugaccaggc ugggucagag uucgagaaca      660

gugacguaag guggguaaua acuguaccgg cgauauggaa gcagccagcg aagcaguuca      720

ugcgccaggc agcguaccag gcgggguuag cgucgccgga gaacagugag caguuaauaa      780

ucgcuuuaga accggaagcg gcgucgauau acugccggaa guuacguuua caccaaauga      840

uagaguuauc aaguaaggcg gcgguuaacg gguacucagg uucggacacu guuggggcgg      900

guuucacgca ggcgaaggag cacauccgac gaaacaggca aucgcgcaca uuccucgucg      960

agaacguuau uggcgagauu uggagugagc uugaggaggg agacaaguac guaguaguag     1020

acucgggugg gggaacuguu gauuuaacgg uacaccaaau uaggcuccca gagggucacu     1080

uaaaggagcu cuacaaggcc acgggugguc cguacgguag ucucgggguu gacuacgagu     1140

ucgagaaguu gcucuacaag aucuucggug aggacuucau agagcaguuu aagaucaagc     1200

guccggcggc guggguagac cucaugauag cuuucgaauc gcgaaagcgc gccgcagcgc     1260

cggaccgaac gaacccuuug aacaucacgu uaccguucuc guucauagac uacuacaaga     1320

aguuccgugg acacucggua gagcacgcgu uacgaaagag uaacguagac uucguaaagu     1380

ggucgaguca ggguaugcuu cgcaugucgc ccgacgcgau gaacgcguua uucaagccua     1440

cuaucgacuc gauaauagaa cacuugaggg acuuauucca gaagccggag guaucgacgg     1500

uaaaguucuu auucuuaguc gggggguucg cagaggcgcc guuguuacag caggcaguuc     1560

aggcggcguu cggugaccag ugccgaauaa uaauacccca ggacguaggg uuaacgaucu     1620

ugaagggggc gguuuuauuc ggguuagacc cggccguaau aaagguucga cguucacccu     1680

ugacuuacgg ugucggcguc uuaaaccgau acguagaggg gaagcaccca ccggaaaagu     1740

uguuagucaa ggacggaaca cgauggugca cggacguauu cgacaaguuc auaucggccg     1800

accaaagugu agcguuaggc gaguuaguaa agcgaucgua uacgccugcc aagccgucgc     1860

aauuaguaau agucaucaac aucuacaguu cggagcacga caacguaagu uuuauaacgg     1920

acccgggagu caagaagugc ggaacauuaa gguuagacuu gacggguacg ucggguaccg     1980

cgguuccagc gcgccgagag auacagacgc ucaugcaguu cggugacacg gagauaaagg     2040

cgacggcgau agacaucgcu acgucuaagu cgguaaaggu cgguaucgac uuucucaacu     2100

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  5848
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt10)

<400>  5848
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuagcaguac ccgagauggg auuacaaggu uuauacauag      120

guucgucgcc cgagcguucg ccgguuccgu cgccuccggg gucgccacgc acgcaagagu      180

cgugcgggau agcaccuuua acuccuuccc agaguccuaa gccggaaguu cgugcaccgc      240

agcaggcauc guucaguguc guagucgcua uagacuucgg uacaacaucg ucggguuacg      300

ccuucucguu cgcuucggac ccggaggcaa uccauaugau gcguaagugg gaggguggug      360

acccuggugu cgcgcaccaa aagacgccua cgugcuuauu auuaacgccu gagggggcgu      420

uccacucguu cggauacacg gcgcgagacu acuaccacga cuuggacccc gaggaggcuc      480

gcgacugguu auacuucgaa aaguucaaaa ugaagauaca cucggcgacu gacuuaacgu      540

uaaagacaca acucgaggcg guuaacggga agacaaugcc ggcguuagag gucuucgcgc      600

acgcguugag guucuuccgc gagcacgcgc uccaggaguu acgagagcaa ucgccgucau      660

ugccggagaa agacacgguc cguugggucu uaaccguccc ggcgaucugg aagcaaccgg      720

cgaaacaguu caugcgagag gcggcuuauu uagcgggguu aguaucgcgu gagaacgcgg      780

agcaauuauu aauagcguua gagccggagg cggcgucagu uuacugucga aaguugcgau      840

ugcaccaguu guuagauuua ucaggaaggg cgccgggagg cgggcgauug ggcgagaggc      900

gaucgauaga cucgucguuc cgacaggcgc gcgagcagcu ccgucguucg aggcauucgc      960

ggacguucuu aguagagucg gguguuggug aguuaugggc ggaaaugcag gcgggugacc     1020

guuacguagu cgcugacugc ggugggggga cgguagacuu aacaguucac caguuagagc     1080

agccacacgg uacguugaaa gagcuuuaca aggcgucagg agggccguac ggggccguag     1140

ggguugauuu agcguucgag caguugcucu gccggaucuu cggcgaggac uucaucgcaa     1200

cauucaagcg ccagcgucca gcggcauggg ucgacuuaac aauagcguuc gaggcacgua     1260

agcggacggc aggaccgcau cgagcgggug cauuaaacau aaguuuaccg uucucguuca     1320

uagacuucua ccggaagcaa cgcggucaca acguagagac ggcgcucagg cgaaguucgg     1380

ucaacuucgu aaaguggagu ucgcagggua uguugcgcau gaguugcgag gcgaugaacg     1440

aguuauucca gccaacaguu ucaggcauua uacagcacau ugaggcauua uuggcgcgcc     1500

ccgagguaca gggggucaag cucuuauucu uggucggagg auucgcggag ucggcaguau     1560

uacagcacgc aguacaagcg gcuuuaggug cgaggggcuu acgcguagua guaccccacg     1620

acgucgguuu gacuauauug aagggcgccg uuuuauucgg ucaggcuccg ggagucguca     1680

ggguucgacg gucuccauua acuuacggug ucgguguauu aaaccguuuc guccccggua     1740

ggcacccgcc ggagaaguua uugguacgag acggucgaag guggugcacg gacguguucg     1800

agcguuucgu agcagcggaa cagucagucg cguuaggaga ggagguaagg cguucguacu     1860

guccugcaag gccaggacag cgucgagucu uaauuaacuu guauuguugc gcagcggagg     1920

acgcacgauu cauaacugac ccggguguac ggaagugcgg ugccuuaagu uuggaguuag     1980

aaccggcgga cugcggucag gacacggcgg gugcaccacc gggucgucga gagauccgag     2040

cagcgaugca auucggugau acugagauaa aggugacggc gguagacguu ucgacuaaca     2100

ggucgguccg agcaucgauc gacuucuuau cgaauugagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  5849
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt10)

<400>  5849
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgcgcgaaa ugacuauacu cgggucugcg gucuuaacgu      120

uacucuuagc agguuacuua gcgcagcagu accuuccucu uccgacaccc aagguaauag      180

gaauagacuu agguacgaca uacugcagug ucggaguauu cuucccggga acugguaagg      240

ucaagguaau accggacgag aacggacaca ucucuauccc gucgaugguc ucguucacgg      300

auaacgacgu uuacgucggg uacgagucgg ucgaguuagc ggacucuaac ccgcagaaca      360

cgaucuacga cgcuaagcga uucaucggua agauauucac ggcggaggag uuagaggcag      420

agauagguag guacccguuc aaggucuuga acaagaacgg gaugguagag uucucaguaa      480

ccucgaacga gacgaucacu guaagucccg aguacgucgg uucacguuua cuauuaaagu      540

ugaaggagau ggcggaggcg uacuugggca ugccgguagc gaacgcagua auaucggucc      600

ccgccgaguu cgacuuaaag caacgaaacu cgacgaucga ggcggcgaac uuagcggggc      660

uuaagauccu ucgagugauc aacgagccga cggcggcggc gauggccuac ggguuacaca      720

aggccgacgu auuccacgug cuugucaucg acuuaggagg ugggacacuc gacgucucgc      780

uuuugaacaa gcagggugga auguucuuga cgcgugcgau gucggguaac aacaaguugg      840

gugggcagga cuucaaccag cgauuauuac aguacuugua caagcaaauu uaccagacgu      900

acgguuucgu cccgucacga aaggaagaga uacaucgauu aaggcaggca gucgagaugg      960

uaaaguugaa cuugacguua caccagucgg cgcaauuaag ugucuuguua acgguugagg     1020

agcaggaccg uaaggagccg cacucgucgg acaccgaguu accgaaggac aaguugucgu     1080

cggcugacga ccacagggua aacucggguu ucggcagggg uuuaucagac aagaagucgg     1140

gcgagucgca gguacucuuc gagacggaga ucagucgaaa guuauucgac acguuaaacg     1200

aggacuuauu ccaaaagauc uuaguuccga uccagcaggu uuuaaaggag ggucacuuag     1260

agaagacgga gauagacgag guugucuugg ucggugguuc gacgcgaauc ccccgaauca     1320

ggcagguaau acaggaguuc uucgggaagg acccaaacac gucggucgau ccggacuuag     1380

cgguuguuac cgguguugcg auucaggccg ggauagacgg ggguucgugg ccguuacagg     1440

uaucagcgcu cgagauaccg aacaagcacu ugcagaagac gaacuucaac ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  5850
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt10)

<400>  5850
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgcgauag ggguccauuu aggguguacg agcgcgugcg      120

ucgcggugua caaagacggg agagccgggg ucgucgccaa cgacgcgggg gauaggguca      180

ccccggccgu cgucgccuau agcgagaacg aggaaaucgu cgggcucgcc gccaagcagu      240

cgcgcauccg caacaucagc aauaccguca ugaaggucaa acaaauauua gggcgcucga      300

guucggaucc gcaggcgcaa aaguauauag ccgagucgaa gugccucgug aucgaaaaga      360

acggcaagcu cagguacgag aucgacaccg gggaggagac caaguucguc aauccggagg      420

acgucgcgcg cuuaauuuuu ucgaaaauga aggagaccgc ccacagcguc cucgggagcg      480

acgccaacga cgucgucauc accgugcccu ucgacuucgg ggaaaaacag aagaacgccu      540

ugggggaggc cgcccgcgcc gccggguuca acguccucag gcucauccau gaacccagcg      600

ccgccuuguu ggccuacggg aucgggcagg auaguccgac cgggaagucg aacauccucg      660

ucuuuaaauu gggggggacc agucucagcu ugucggugau ggaggucaau ucggggaucu      720

acagagucuu gagcacgaau accgacgaca auauaggggg ggcccauuuu accgagacgc      780

ucgcccaaua cuuggccagc gaauuucagc gcaguuuuaa gcacgacguc cgcgggaacg      840

ccagggcgau gaugaagcuc accaauucgg ccgaggucgc caaacacagc cucagcacgc      900

ucgggucggc gaauugcuuu uuggauagcc ucuacgaggg gcaggacuuc gacuguaacg      960

ucagucgcgc ccgcuucgag uuguugugca gcccguuguu caacaaaugc aucgaggcca     1020

uacgcggguu gcucgaccag aacggguuua ccgccgacga cauaaauaaa gucguguugu     1080

gcgggggcag cagcaggaua ccgaaauugc aacaauuaau caaggacuug uuuccggccg     1140

ucgaauuguu gaacagcaua ccgccggacg aggucauacc gaucggggcc gccaucgagg     1200

ccgggaucuu gaucggcaag gagaauuuac ucgucgaaga uagcuugaug aucgaaugca     1260

gcgcgcgcga cauccucguc aaaggggucg augagagcgg ggcgucgcgc uuuaccgucu     1320

uauucccgag cggcaccccg cucccggcca ggcgccagca uacccuccaa gcgccggggu     1380

cgaucagcag cgucuguuug gaguuguacg aaagcgacgg caaaaauagc gcgaaagaag     1440

agacgaaauu cgcccaaguc gucuugcaag aucucgauaa gaaggagaac gggcucaggg     1500

acauccucgc cgucuugacc augaagcgcg acgggagccu ccacgucacc uguaccgacc     1560

aagaaaccgg gaagugcgag gccauaagca ucgaaaucgc cagcugagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  5851
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt10)

<400>  5851
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgugguag gacucgacgu cgggagccaa agcugcuaca      120

uagcgguagc cagggcaggc gggauagaga cgaucgccaa cgaguucucc gaucgcugca      180

cacccagcgu caucagcuuu gguucuaaaa acaggacuau aggaguggcc gcgaaaaacc      240

aacaaauaac ccaugcaaac aacaccguca gcaacuucaa acgauuccac ggacgugccu      300

ucaacgaccc guuuauacaa aaagaaaaag aaaaccuauc cuacgaccua gucccccuca      360

agaauggagg cgugggcauc aaaguuaugu auaugggaga agaacacuug uucucaguag      420

aacagauaac cgccaugcua cuaacaaaac ugaaggaaac cgcagagaac agucugaaga      480

aaccugucac cgacugcgua aucuccguac ccuccuucuu caccgacgca gaacggagau      540

ccguacuaga cgcagcccaa auaguaggcc uaaacugccu ccgcuugaug aacgauauga      600

cggccguagc acucaacuau gggauuuaca aacaagaccu cccaagccuc gacgaaaaac      660

cccgcauagu agucuucguc gacaugggac acucagcauu ccagguaagc gcaugcgccu      720

ucaacaaagg aaaacucaaa gucuuaggca cggcuuucga ccccuuccua ggcgggaaaa      780

auuucgacga gaaacucguc gaacacuucu gcgccgaguu caaaaccaaa uacaaacucg      840

acgcaaagag caaaauccga gcccuccuac gcuuauacca ggaaugcgaa aagcuaaaga      900

aauugauguc cuccaacucc accgaccuac ccuuaaacau cgaauguuuc augaacgaca      960

aggacgucag cggaaagaug aacagauccc aguucgagga gcucugcgcc gaguuauuac     1020

aaaagauaga agucccccuc uacagccuuc ucgaacagac ccaccucaaa guagaagacg     1080

uuucagccgu cgaaaucguc ggcggagcaa cacgcauccc cgcggucaaa gaacgcaucg     1140

ccaaauucuu cgggaaggac auauccacca cccuaaacgc agacgaagca guggcacgcg     1200

ggugugcccu ccagugcgcc aucuuaagcc ccgcauucaa aguacgagag uucucaguaa     1260

ccgaugccgu cccguuccca auaagccuga uauggaacca cgacagcgag gacaccgaag     1320

guguccacga agucuucagu cgaaaccacg cggccccauu cucaaaagua uuaacguucc     1380

uccgacgcgg acccuucgaa cucgaagcau ucuacagcga cccgcaaggc guaccguacc     1440

cugaggcaaa gauuggcagg uucguagucc agaacgucuc cgcacaaaaa gauggcgaga     1500

aaagccgcgu aaaggucaaa guccgaguca auacacacgg aaucuucacc auuuccaccg     1560

ccucaauggu agaaaaaguc cccacagaag aaaacgagau gagcucugaa gccgacaugg     1620

agugccucaa ccaacgccca cccgaaaacc ccgacaccga caagaacguc caacaagaca     1680

acagcgaagc aggaacccag ccccaagucc aaaccgacgc acaacagacc agccagagcc     1740

cacccucccc cgagcucaca ucagaagaaa auaagauccc agacgcagac aaggccaacg     1800

aaaagaaagu cgaccagccc ccggaggcca agaaacccaa aaucaaagug gucaacguag     1860

aacuccccau cgaagcaaac cuggucuggc agcuagguaa agacuuauua aacauguaca     1920

ucgaaaccga aggcaaaaug auaaugcaag auaaacucga aaaagaacgc aacgacgcca     1980

aaaacgcagu cgaagaauac guauacgagu uccgggacaa auuaugcggc ccauacgaaa     2040

aauucaucug ugaacaagac caccaaaacu uucuacguuu auuaaccgaa accgaagacu     2100

ggcucuacga agaaggcgaa gaucaagcaa aacaggcuua cgucgauaaa cucgaagaac     2160

uaaugaaaau cggaacgccg gucaaagugc gguuccaaga agcagaagaa cgucccaaaa     2220

uguucgagga acucggacaa agacuccaac acuacgcgaa aaucgccgcc gacuuccgca     2280

acaaagacga gaaguacaac cacaucgacg aaucagaaau gaagaaagua gaaaagucgg     2340

ucaacgaagu aauggaaugg augaacaacg uaaugaacgc ccaagccaaa aagucccucg     2400

accaagaccc agucguccga gcacaagaaa ucaaaaccaa aauuaaggaa cucaacaaua     2460

ccugcgagcc cgucguaacg caaccgaaac caaaaauaga aucccccaaa cucgaacgaa     2520

cccccaacgg gccgaacauc gacaagaaag aagaagaccu cgaggacaaa aacaacuucg     2580

gagcagaacc accacaccaa aacggcgaau gcuacccaaa cgagaaaaac agcgucaaca     2640

uggaccucga uugaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  5852
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt10)

<400>  5852
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgauaagg uccgccgcca acgcccccgc cgcagggugu      120

gcugggcgcu cgucgccguc uugcucgccg auuuacucgc cuuaucggac accuuagccg      180

ucaugagcgu cgauuuaggg ucggaaagua ugaaagucgc gaucgugaag ccgggggucc      240

cgauggagau cgugcucaac aaagagagca gacgcaagac ccccgucaua gucacguuaa      300

aggagaacga gcgcuuuuuc ggggauucgg ccgccucgau ggccaucaaa aacccgaaag      360

ccaccuugag guauuuucaa cauuuguuag gcaaacaagc cgacaauccg cacgucgccu      420

uguaucaagc gagguuuccc gaacaugaau uaaccuuuga uccgcaacgc caaaccgucc      480

auuuccaaau aucgagccaa uuacaauuua gcccggaaga gguccucggg auggucuuga      540

acuacagcag gagcuuggcc gaggacuucg ccgaacaacc gauaaaagac gccgucauaa      600

cggucccggu guuuuuuaau caagcggaaa ggagggccgu cuuacaagcc gccaggaugg      660

ccggguugaa ggucuuacaa uugauaaacg auaauacggc gaccgcguug ucguacgggg      720

uguuuaggag aaaggacauc aauacgaccg cgcaaaacau aauguuuuac gauaugggga      780

gcgggucgac ggucuguacg aucgucacgu aucaaauggu caaaaccaaa gaggccggca      840

ugcaaccgca auuacaaaua agaggggucg gguucgauag gacguuaggc ggguuagaaa      900

uggaauugag auugagggag agguuagccg gcuuguuuaa cgaacaaagg aaagggcaac      960

gcgccaaaga cgucagagaa aaucccaggg cgauggcgaa auuauuaagg gaagccaaca     1020

gauugaagac gguguugucg gcgaaugccg aucauauggc ccaaaucgag ggguuaaugg     1080

acgacgucga uuuuaaagcc aaggucacca gggucgaguu cgaagaacuc ugcgccgauc     1140

ucuucgaaag agucccgggc ccgguccaac aagcguugca aucggcggag augucguuag     1200

acgaaaucga acaagucaua uuagucgggg gcgcgaccag agugccgcgc guccaagaag     1260

ucuuauuaaa agcggucggg aaagaagaau uaggcaaaaa uauaaacgcc gacgaggccg     1320

cggcgauggg cgccgucuau caagccgccg ccuugucgaa ggcguucaag gucaaaccgu     1380

ucguggugag ggacgccguc guguauccga uauuagucga auuuacccgc gaagucgaag     1440

aagaaccggg cauccauucg uuaaaacaua acaagagagu cuuguuuagc agaaugggcc     1500

cguauccgca gaggaaggug auaacguuca auagguauuc gcacgacuuu aauuuucaua     1560

uaaauuaugg ggauuuaggg uuuuuaggcc cggaggacuu gagagucuuc gggagucaaa     1620

acuuaacgac cgucaaauug aagggcgucg gggauucguu uaaaaaauac ccggauuaug     1680

aaaguaaagg gauaaaagcc cauuuuaauu uagacgaauc gggggucuug ucguuggauc     1740

gcgucgaaag cgucuucgaa accuuagucg aagauucggc cgaggaagag agcaccuuga     1800

cgaaguuggg gaauacgauc aguucguuau ucgggggggg gacgaccccg gacgcgaaag     1860

aaaacgggac cgacaccgug caagaagagg aagaaucgcc ggccgaaggc ucgaaagaug     1920

aaccgggcga acaagucgaa uugaaagaag aggccgaagc gccggucgaa gacgggagcc     1980

aaccgccgcc gccggagccg aaaggggacg ccacgccgga aggggagaaa gcgaccgaga     2040

aggagaacgg cgauaaaagc gaagcgcaaa agccgucgga aaaagccgaa gccggcccgg     2100

aagggguggc cccggcgccg gaaggggaaa aaaaacaaaa accggcgcgc aaaagaagga     2160

uggucgaaga aauaggcguc gaauuagucg ucuuagauuu accggaucuc ccggaagaca     2220

aauuagccca aagcguccaa aaguugcaag aucucaccuu gagggauuua gaaaaacaag     2280

agagagagaa ggccgcaaau ucgcucgagg ccuuuaucuu cgaaacgcaa gauaaauuau     2340

aucaaccgga auaucaagag gucaguaccg aagaacaaag ggaagaaaua agcggcaaau     2400

ugucggcggc caguacgugg uuagaagacg aaggggucgg ggcgacgacc gucaugcuca     2460

aagaaaaauu agccgaauua cgcaaauuau gucagggcuu auucuucaga gucgaagaaa     2520

ggaaaaaaug gccggagaga uuaagcgcgu uggacaacuu guugaaucac aguucgaugu     2580

uuuugaaagg cgcgagauug auaccggaaa uggaucaaau auuuaccgaa gucgaaauga     2640

ccacccucga aaaggugaua aacgaaacgu gggcguggaa aaacgccacc uuagcggaac     2700

aagccaaauu accggcgacc gaaaaaccgg uccucuugag caaggauauc gaggccaaaa     2760

ugauggcguu agauagggaa guccaauacu uauugaacaa agcgaaauuc acgaaaccga     2820

gaccgagacc gaaagauaaa aacggcacga gagccgaacc gccguugaac gcgucggcgu     2880

cggaucaagg cgaaaaagug auaccgccgg ccgggcaaac cgaggacgcc gaaccgauca     2940

gcgagccgga aaaggucgaa accgggagug aaccggggga uaccgaaccg cucgaacucg     3000

gggggccggg ggccgagccg gagcaaaagg agcagagcac cgggcaaaaa agaccgcuca     3060

aaaaugauga guugugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  5853
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt10)

<400>  5853
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggaggaga cgcaaacgca ggaucagccg auggaggaag      120

aggagguaga gacauucgca uuccaggcgg agauagcaca auuaaugucg uuaauaauua      180

acacguucua caguaacaag gagauauucu uaagggaguu aauaucgaac ucgucggacg      240

cguuggacaa aauacgauac gaaucguuaa cggacccguc gaaguuagac ucggguaagg      300

aguugcacau caacuuaauu ccgaacaagc aggaccggac guuaacgaua guagacacgg      360

guauaggaau gacgaaagcg gacuugauaa acaacuuagg aacgauagcg aagucgggua      420

cuaaggcguu cauggaggca uuacaggcgg gugcggacau aaguaugaua ggucaauucg      480

gggucggauu cuacucggca uacuuagucg cagagaaggu aacgguaauc acgaagcaca      540

acgacgacga acaauacgcc ugggagaguu cggcgggugg uaguuucacg guacgcacug      600

acacggguga gccgaugggu agggguacga agguaauauu acacuuaaag gaggaccaga      660

cggaauacuu agaggagcgc cggaucaagg agauuguuaa aaagcacucg caauucaucg      720

gcuacccuau aacguuauuc gucgagaagg agcgcgacaa ggagguuagu gacgacgagg      780

cggaggagaa agaggacaag gaggaggaga aggaaaagga ggagaaggag ucggaggaca      840

agccggagau agaggacgua ggaucggacg aggaggagga gaagaaggac ggggacaaaa      900

agaagaagaa aaagauaaag gagaaauaca uagaccaaga ggaguuaaac aagacgaagc      960

cgaucuggac aaggaacccg gacgacauaa cgaacgagga guacggugag uucuacaagu     1020

cguuaacaaa cgacugggag gaccacuuag cggucaaaca cuucagugua gaggggcagu     1080

uagaguuccg cgcguuguua uucguaccga ggcgcgcgcc guucgacuua uucgagaacc     1140

ggaagaagaa aaacaauaua aaguuauacg uccgaagggu auucauaaug gacaacugcg     1200

aggaguuaau uccggaguac cucaacuuca uacgcggugu cgucgacucg gaagacuugc     1260

cguuaaacau cucgcgagag auguuacagc agucgaagau cuuaaaggua auacgcaaga     1320

acuuagucaa gaagugcuua gaguuauuca cggaguuggc agaggacaag gagaauuaca     1380

aaaaauucua cgagcaguuc ucgaagaaua uaaaguuagg gauacacgag gacagucaga     1440

accgaaaaaa guuaucagaa uuauuacgau acuauacgag ugcgucgggg gacgaaaugg     1500

ucaguuugaa ggacuauugu acacggauga aggaaaacca aaagcacaua uacuacauaa     1560

cgggggagac gaaggaccaa guugcgaacu cggcauucgu cgagcgcuua cggaagcacg     1620

gguuagaggu cauauacaug aucgaaccua uagacgagua uugcguacag caauugaagg     1680

aguucgaggg gaagacauua guaaguguaa caaaggaggg guuagaguug ccggaggacg     1740

aggaggagaa gaagaagcag gaggagaaga agacgaaguu cgagaacuua ugcaagauaa     1800

ugaaggacau auuagagaag aaggucgaga aggucgucgu cucuaacagg uugguaacgu     1860

cgccgugcug cauaguaacg ucgacuuacg guuggacugc gaacauggaa cgaauaauga     1920

aggcgcaggc guuaagggac aacaguacga uggguuacau ggcggcaaag aagcauuuag     1980

aaaucaaccc ggaccacucg aucauagaga cguuacgaca gaaggcggag gcggacaaga     2040

acgacaagag ugucaaagac uuaguaauau uauuauacga gacggcguug uuaucgagug     2100

gguucucguu agaggaccca caaacucacg cgaaccgaau auaucgcaug auaaaguugg     2160

gauuaggaau cgacgaggac gacccgacgg cggacgacac aucggcggcc guaaccgagg     2220

agaugccgcc guuagagggu gacgacgaua cuucgcggau ggaggaggua gacugaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  5854
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt10)

<400>  5854
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggaggagg uccaucaugg cgaggaagag guggagacgu      120

uugcguuuca agcggaaauc gcgcaguuga ugucgcucau aaucaauacg uuuuauagua      180

auaaggagau auuuuugcgc gaacucauca gcaaugccuc ggaugcguua gauaaaaucc      240

gcuaugaguc guugaccgau ccgagcaagu uagauagcgg gaaagaacuc aagaucgaua      300

uaauaccgaa uccgcaggag aggaccuuga cguuggucga uacggggauc gggaugacca      360

aggcggauuu gaucaauaac uuggggacca ucgcgaaauc gggcaccaag gcguuuaugg      420

aagcguugca ggccggggcg gauaucucga ugauagggca guuugggguc ggguuuuauu      480

cggccuauuu gguggcggag aaagucgucg ucauaaccaa gcauaaugau gaugagcagu      540

augcguggga gucgucggcg gggggcucgu uuaccgugcg cgccgaucau ggggagccga      600

ucgggagggg caccaagguc auauugcauu ugaaagagga ucagacggag uaucucgagg      660

aaaggcgcgu gaaagaggug gugaagaagc auucgcaauu uauaggguau ccgaucacgu      720

uguauuuaga gaaggaacgc gagaaagaga ucucggauga ugaagcggaa gaggagaagg      780

gggagaagga ggaggaggau aaggaugaug aggagaaacc gaaaauagag gaugucgggu      840

cggaugagga ggaugauagc gggaaagaua aaaagaagaa gaccaagaag auaaaggaaa      900

aguauauaga ucaggaggaa uuaaauaaga ccaagccgau auggacgcgc aauccggacg      960

auauaaccca ggaggaguau ggcgaguuuu auaagagcuu gaccaaugau ugggaagauc     1020

auuuggccgu caaacauuuu ucggucgagg ggcaguugga guuucgcgcc uuguuguuua     1080

uaccgcgccg cgccccguuu gauuuauuug agaauaaaaa gaagaagaau aauaucaaau     1140

uguaugugag gaggguguuu aucauggaua gcugugauga guuaauaccg gaguauuuga     1200

auuuuauaag aggggucguc gauagugagg auuugccguu gaauauaucg agggagaugu     1260

ugcagcaauc gaaaaucuua aaggucauac gcaagaauau agucaagaaa uguuuggagu     1320

uguuuucgga gcucgccgaa gacaaggaga auuauaaaaa guuuuaugag gcguuuucga     1380

aaaauuugaa guuagggauc caugaggauu cgacgaacag gcgcagguug ucggaguugu     1440

ugcgcuauca uaccucgcaa ucgggggaug aaaugaccuc guugagugag uaugucucga     1500

gaaugaagga gacccagaaa agcaucuauu auauaacggg ggaaucgaaa gagcaggucg     1560

ccaauagcgc cuuuguggag agggucagga aaaggggguu ugaggugguc uauaugaccg     1620

aaccgauaga ugaauauugc guccagcaau ugaaggaguu ugaugggaag ucguugguga     1680

gcgucacgaa ggagggguug gagcucccgg aggaugagga ggaaaaaaag aagauggagg     1740

agagcaaggc gaaguuugaa aaucucugua aauuaaugaa ggaaauauug gauaagaaag     1800

ucgagaaagu gaccauaagc aauagauuag ucucgagccc guguuguaua gugaccucga     1860

ccuaugggug gaccgccaau auggagagga ucaugaaggc ccaggcguug cgcgauaaua     1920

gcacgauggg cuauaugaug gcgaaaaagc auuuggagau caauccggau cauccgaucg     1980

ucgagaccuu gcgccagaaa gcggaggccg auaagaauga uaaggcgguc aaggauuugg     2040

ucguguuauu guuugagacc gcguuguuga gcucgggguu cagcuuagaa gauccgcaga     2100

cgcauucgaa ucgcauauau aggaugauca aauugggguu agggaucgau gaagaugagg     2160

ucgcggccga ggaaccgaau gccgccgugc cggaugagau acccccguua gagggcgaug     2220

aagaugccag ccgcauggag gaaguggauu gaggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  5855
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt10)

<400>  5855
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcgcguugu gggucuuggg uuuguguugu gucuuguuga      120

cauuugggag cgugagggcc gaugaugaag uggauguaga ugggaccgug gaggaagauu      180

uggggaaguc gagggagggg ucgagaaccg acgaugaagu gguacaaagg gaagaggaag      240

ccauccaauu ggacggguug aaugcgucgc aaaucaggga auugagagaa aaaucggaga      300

aauucgcguu ucaggcggag gugaaucgca ugaugaaguu gauuauaaau aguuuguaua      360

agaacaagga aaucuuuuua agagaguuga uaaguaaugc gucggacgcg cucgacaaaa      420

ucagguugau aucguuaacc gaugagaacg cgcucucggg caaugaagag uugacgguca      480

agaucaaaug ugauaaagaa aaaaauuuau ugcacgucac cgauacaggg gucgggauga      540

cgagggagga auuggugaag aauuugggga cgaucgcgaa aucggggacc ucggaauuuu      600

ugaauaagau gaccgaagcg caagaggaug ggcaaagcac cucggaauug aucgggcaau      660

uuggcgucgg cuuuuauucg gccuuuuugg ucgccgauaa agucaucgug accucgaagc      720

auaauaauga cacgcaacau auuugggaaa gcgauucgaa ugaguucucg gucauagccg      780

aucccagagg gaauaccuug gggcgcggga cgacgauaac cuuggucuug aaagaggaag      840

ccagcgauua uuuggaguua gauaccauaa agaauuuggu caaaaaguac ucgcaauuua      900

uuaauuuucc caucuaugug uggucgagca aaaccgagac cgucgaagaa ccuauggaag      960

aagaagaagc cgcgaaggag gaaaaggagg agagcgacga ugaggccgcc guggaagagg     1020

aggaagagga aaagaaaccg aaaacgaaaa aggucgaaaa gacggucugg gauugggagu     1080

ugaugaacga uauuaagccg aucuggcaaa ggcccucgaa ggagguggaa gaggaugaau     1140

auaaggcguu uuauaaaucg uuuucgaaag agucggacga uccuauggcg uacauccauu     1200

ucaccgcgga gggggaaguc accuuuaagu cgauauuguu ugugccuacc ucggcgccgc     1260

gcggguuguu cgaugaguau ggcucgaaaa aaucggauua uauaaaguug uauguaagga     1320

gagucuuuau uacggaugau uuucaugaua ugaugccgaa auauuuaaau uucgugaaag     1380

gggucgucga cagcgacgau uuaccguuga acgucucgcg cgaaaccuug caacaacaua     1440

aguuauugaa agucaucagg aaaaaauugg ugcgcaagac cuuggauaug auaaaaaaaa     1500

ucgccgacga caaauauaac gauaccuuuu ggaaggaauu ugggacaaau auuaaguugg     1560

gggucauaga ggaucauucg aacaggaccc gcuuggccaa guuguugcgc uuucaaucgu     1620

cgcaccaucc gaccgauauc accucguuag aucaauacgu cgagaggaug aaagagaagc     1680

aagauaagau auauuuuaug gccgggaguu cgaggaagga agccgagucg ucgccguucg     1740

ucgaaagguu guugaaaaaa ggguacgagg ugauauaucu cacggagccg gucgaugagu     1800

auuguauaca agcguugccg gaauuugaug ggaaacgcuu ucaaaacgug gccaaagagg     1860

gggucaaauu ugaugagucg gaaaaaacca aagaaagccg cgaggccgug gaaaaggaau     1920

uugaaccguu auugaauugg augaaggaua aggcauugaa agauaaaauc gagaaagccg     1980

ucgucagcca aagauuaacg gaaucgccgu gcgcguuggu ggcaucgcaa uauggguggu     2040

cggguaauau ggaacgcaua augaaagccc aagcguauca aaccgggaaa gauauaucga     2100

cgaauuauua ugcgucgcaa aaaaaaaccu uugagauaaa uccgcgccau cccuugauuc     2160

gcgauauguu gaggcgcaua aaagaggaug aagacgauaa aacggucuug gauuuggcag     2220

uagucuuguu ugagaccgcg accuugcgcu cgggguauuu auugccggau accaaggcgu     2280

auggggauag gauagagagg auguugcgcu ugucguugaa uaucgauccg gacgccaaag     2340

ucgaggaaga accggaagaa gaaccggagg aaaccgccga agauacgacg gaagauaccg     2400

aacaagauga agacgaagaa auggacguag ggaccgauga ggaagaggag acggccaaag     2460

agagcacggc cgagaaagau gaguugugag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  5856
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt10)

<400>  5856
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgagggagc ucagggcguu guuguugugg gggaggaggu      120

ugaggccguu guugagggcg ccggccuugg cggccgugcc gggggggaag ccgaucuugu      180

guccgaggcg caccaccgcc caguuggggc cgaggaggaa uccggcgugg agcuugcaag      240

cggggagguu guuuaguacc cagacggcgg aggauaagga ggagccguug cauucgauca      300

uaucgucgac ggaaaguguc caggggucga cgaguaagca ugaauuucaa gcggagacga      360

aaaaguuguu ggauauaguc gcgaggucgu uguauaguga gaaggaggug uuuauaaggg      420

aguugauaag caaugccagu gaugccuugg agaaguugag gcauaaguug gucagcgaug      480

ggcaggccuu gccggagaug gagauccacu ugcagacgaa ugccgagaag gggacgauca      540

ccauccagga uaccgggauc gggaugaccc aagaagaguu ggugagcaau uuggggacca      600

ucgcgagguc ggggucgaag gcguuuuugg augcguugca gaaucaggcg gaggcgagua      660

guaagauaau agggcaauuu ggggucgggu uuuacagugc guuuaugguc gccgauaggg      720

uggaggucua cagcaggagc gccgcgccgg ggaguuuggg guaucagugg uugagugaug      780

ggucgggggu cuuugagauc gccgaggcga gcggggugag gaccgggacg aagauaauaa      840

uccauuugaa gucggauugu aaggaguucu cgagcgaggc gagggugagg gaugugguga      900

cgaaguacag caacuuugug agcuucccgu uguacuugaa ugggcgcagg augaauaccu      960

ugcaggcgau auggaugaug gauccgaagg augugaggga guggcaacac gaggaauuuu     1020

auagguaugu cgcccaggcc caugauaagc cgagguauac guugcauuau aagaccgaug     1080

cgccguugaa uauaaggagu auauuuuaug uccccgauau gaagccgucg auguuugaug     1140

ucaguaggga guuggggagc agcgucgccu uguauagccg caagguguug auccagacca     1200

aggcgacgga uauauugccg aagugguuga gguuuauacg cgggguggug gauucggagg     1260

auauaccguu gaauuugagc agggaguugu ugcaggagag ugcgcucaua aggaaguuga     1320

gggaugucuu gcagcaaagg uugaucaagu uuuuuauaga ccagaguaaa aaggacgccg     1380

agaaguaugc gaaguuuuuu gaggauuaug gguuguuuau gagagagggg auagucaccg     1440

ccacggaaca ggaagugaag gaagauaucg ccaaguuguu gcgcuaugaa aguucggcgu     1500

ugccgagcgg gcaguugacc ucguugucgg aguaugcgag caggaugcgc gccgggacga     1560

ggaauauaua uuauuugugu gcgccgaaua ggcauuuggc cgagcauagc ccguauuaug     1620

aagcgaugaa gaaaaaggau acggaggugu uauuuuguuu cgagcaguuu gaugaguuaa     1680

cguuguugca uuugcgcgaa uuugauaaga aaaaguugau aucgguggaa accgauauag     1740

uggucgauca uuauaaggag gagaaguuug aagauagguc gccggcggcc gaguguuuga     1800

gcgagaagga gacggaggag uugauggcgu ggaugagaaa uguguugggg agucgcguca     1860

cgaaugucaa ggugaccuug cgcuuggaua cgcauccggc gauggugacg gucuuggaga     1920

ugggggccgc gaggcauuuu uugaggaugc agcaguuggc caagacccaa gaagagaggg     1980

cgcaguuguu gcagccgacg uuggagauca auccgaggca ugcguugauc aaaaaguuga     2040

accaguuacg cgcgagugaa ccgggguugg cgcaguuguu gguggaucaa auauaugaga     2100

augcgaugau agccgccggg uuggucgaug auccgagggc gauggucggg agguugaacg     2160

aguuguuggu gaaggccuug gaaaggcacu gaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  5857
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt10)

<400>  5857
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gguaagaucu cgucauuacc gacgcaguug uucaagugcu      120

gcuucugcga cuucuuaaag guaaagaugc acacgauguc gaguucccac uuauucuacu      180

uggccuuaug cuuguugacg uucaccuccu cggcgaccgc agggccggag accuugugcg      240

gcgcggaguu aguagacgcg uuacaguucg ucugcgguga ccgagguuuc uacuucaaca      300

agccgacggg uuacgggucc ucgucgcgcc gugcaccgca gacgggcauc guugacgaau      360

gcugcuuccg uucuugcgac cuccgucgcu uagagaugua cugcgcgccg uugaagccgg      420

cgaagucggc ccguucggua cgcgcgcagc ggcacacgga caugccaaag acgcagaaag      480

agguccacuu aaagaacgcg ucgcguggau cggccggcaa caagaacuac cggaugugag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  5858
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt10)

<400>  5858
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcauaccca uggguaaguc aauguuggug uuauuaaccu      120

ucuuagccuu cgccucgugc ugcaucgcgg ccuaccgucc gucagagacc cuaugcggcg      180

gggagcuagu agacacgcua caguucgugu gcggcgaccg gggguucuac uucucgcgcc      240

ccgcgucgcg cgugucccgc cguucgcgcg gcaucguaga ggagugcugc uuccgaucau      300

gcgacuuggc cuuauuagag accuacugcg ccaccccggc caagucggag cgagacgugu      360

cgacgccgcc gaccguguua ccggacaacu ucccccggua ccccgucggc aaguucuucc      420

aguacgacac guggaagcag ucgacucaga gacuucgucg cggguuaccg gcguuguugc      480

gugcccgacg aggccacgug cuagccaagg aguuagaggc guuccgcgag gcgaagcggc      540

accgcccguu aaucgcguua cccacucagg accccgcgca cggaggcgcc ccgcccgaga      600

uggcgucgaa ccgaaaguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  5859
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt10)

<400>  5859
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacucguuca guacgucggc guucggcccc gucgcguucu      120

cguuagguuu guuauugguc uuaccggcgg cguucccagc gcccguucca ccgggugagg      180

acucgaagga cguugcggcg ccccaccgac agcccuugac cucguccgag cguaucgaca      240

agcagauccg auacaucuua gacgguauaa gugcguuacg caaggagacg ugcaacaaau      300

cgaacaugug cgagaguucg aaggaggcgu uagccgagaa caaccucaac uugccgaaga      360

uggcggagaa ggacgggugc uuccagagug gguucaacga ggagacaugc uuaguaaaga      420

ucauaacggg ccuccuugag uucgaggucu accucgagua cuuacagaac agguucgagu      480

caucggagga gcaggcacgc gcgguucaaa ugucgacgaa gguauugauc caguuccucc      540

agaagaaggc caagaacuua gacgcgauca cgacgccgga cccgacuacc aacgcgaguu      600

uguuaacuaa guuacaggcg cagaaccagu gguugcagga caugaccacc cacuugaucu      660

ugcggucguu caaggaguuc uugcagaguu cuuuaagagc guuaaggcag augugaggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  5860
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt10)

<400>  5860
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccguuauugu gguuaagggg guucuuguua gcgucgugcu      120

ggaucaucgu gcguucgucg ccgacgcccg ggucggaggg ucacucggcc gcaccggacu      180

gcccaaguug cgcacuugcc gcguuaccga aggacguucc gaacucgcag ccggagaugg      240

uugaggccgu gaaaaagcac auauugaaca uguuacaccu aaagaagcga ccggacguaa      300

cgcagccggu ccccaaagcg gcccuauuaa acgcuauacg gaaguuacac guugggaagg      360

uaggcgagaa cgguuacgug gagaucgagg acgacaucgg gcgccgcgcc gagaugaacg      420

aguuaaugga gcagacguca gagaucauca ccuucgcgga gucgggcacu gcgcguaaga      480

cuuugcacuu cgagaucucg aaggaggguu cggacuuauc ggugguagag cgggccgagg      540

ugugguuauu cuugaaggug ccgaaggcga accgaacgcg aaccaagguc accauccgau      600

uguuccagca acagaaacac ccccagggga guuuagacac cggggaggag gccgaggagg      660

uaggucucaa gggggagcga uccgagcucc ucuuaucgga gaaggugguc gacgcgcgaa      720

agucuacgug gcacguauuc ccggugucgu cgucgaucca gcgccuacuu gaccagggca      780

agaguucguu ggacguccgc auagcgugcg agcagugcca ggagucgggc gcgucucuug      840

uauuguuagg gaagaagaag aagaaggagg aggaggguga ggggaagaag aaggggggcg      900

gggagggcgg ggcgggcgcg gacgaggaga aggagcaguc ucaccggccg uucuuaaugu      960

uacaagcgcg ucaaucggag gaccacccgc accgacgacg ccgacguggg uuagagugcg     1020

acggcaaggu gaacaucugc ugcaagaagc aguucuucgu uucauucaag gacaucgguu     1080

ggaacgacug gauaauagcc ccgucggggu accacgcgaa cuacugcgag ggcgagugcc     1140

cgucccacau cgccgguacu ucgggcucgu cguuaucguu ccacaguacg guuauaaacc     1200

auuaccguau gcguggacac ucccccuucg cgaacuugaa gaguugcugc gugccgacca     1260

aguugcgucc caugucgaug cuuuacuacg acgacggcca gaacauuaua aagaaggaca     1320

uccagaacau gaucgucgag gaaugcggcu gcaguugagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  5861
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt10)

<400>  5861
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacgguuuac cgggacgagc uuugggugcg gcuuguuugu      120

uauuguuggc agcggguugg uuaggcccgg aagcgugggg aucgccgaca ccucccccua      180

cuccggcggc gccaccgccc ccgccaccgc cggggucgcc aggcgggucc caagauacuu      240

gcacaaguug cggggguuuc cgacgacccg aggaauuggg acgcguagac ggugauuucu      300

uggaagcugu aaagcgucau aucuuaucgc guuuacagau gcgagggcga ccgaacauaa      360

cccacgccgu accgaaggcg gcgaugguua ccgcguuacg aaaguuacau gcugggaagg      420

uucgugagga cgggcgugua gagauccccc auuuggacgg gcacgccucg ccaggggccg      480

acgggcaaga gcgagucucg gagauaauua guuucgcgga gacugacggg uuagcgucgu      540

cgaggguacg uuuauacuuc uucauaucga acgaggguaa ccaaaacuug uucguaguac      600

aggcgaguuu augguuauac cuuaagcuau uaccauacgu uuuagagaag gggucgcguc      660

gaaaaguaag gguaaaggua uacuuccaag agcaagguca cggcgaccga uggaacaugg      720

uagagaagcg gguugaccuu aagcgaagug gauggcacac guucccguua acugaggcaa      780

uacaggcauu auucgagcgu ggagagcgcc gcuuaaacuu agacguacaa ugcgacucgu      840

gccaggaguu ggcagucguc ccaguauucg uagaccccgg ggaggagagu caucgaccgu      900

ucguaguagu acaggcgcgc uuaggugacu cgcgacaccg aauccggaag cgugguuuag      960

agugcgacgg uaggacgaac uugugcugcc gacagcaguu uuuuauagac uuuagguuga     1020

ucggguggaa cgacuggaua auugcgccga caggauacua cgguaacuau ugcgaaggaa     1080

guugcccggc guacuuagcg ggggugccag guucggcauc gucguuccac acugcgguag     1140

uuaaccagua ccgaaugcga ggauugaauc cggggacagu aaacucgugc ugcaucccga     1200

cgaaguuaag uacgaugucg auguuauacu ucgacgacga guacaacaua guaaagcgcg     1260

acgucccgaa caugaucgua gaagagugcg guugcgcgug aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  5862
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt10)

<400>  5862
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcguugaggg uccucuuauu gaccgccuug accuuaugcc      120

auggguuuaa uuuggauacg gagaacgcca ugacguuuca ggagaaugcc aggggguuug      180

ggcagagcgu cgugcaguug caggggagca gggucguggu gggggcgccg caggaaaucg      240

uggccgccaa ucagaggggg agcuuguauc agugugauua uagcacgggc agcugugagc      300

cgauacgcuu acaggugccg guggaggccg ugaauauguc guuaggguug ucguuggcgg      360

cgaccacgag cccgccgcag uugcucgccu gugggccgac ggugcaccaa acguguagcg      420

agaauacgua ugucaagggg uuguguuucu uguucggcag uaauuugagg caacaaccgc      480

agaaguuucc ggaggcguug agggggugcc cccaggagga uucggauauc gcguucuuga      540

ucgaugggag ugggaguauc aucccgcaug auuuuaggag aaugaaagag uucgugagca      600

ccgucaugga gcaguugaaa aagaguaaga ccuuguuuag uuuaaugcag uauucggaag      660

aauuucgcau acauuuuacg uuuaaggaau uucaaaauaa uccgaauccg aggagcuuag      720

ucaagccgau cacccaguug uuggggcgca cccauaccgc gaccgggaua cgcaaagugg      780

ucagggaguu guuuaauauc accaacgggg ccaggaagaa ugcguuuaag auauuggucg      840

ugaucacgga uggggagaag uuuggcgauc cgcucgggua ugaggauguc auaccggagg      900

ccgaucgcga aggggucaua agguauguga uaggggucgg cgaugcguuu aggucggaga      960

agaguaggca agaguugaau accaucgcga guaagccccc gagggaucau guguuucagg     1020

ugaauaauuu ugaggcguug aagacgauac agaaucaguu gagggaaaag aucuuugcga     1080

ucgaggggac gcagacgggg ucgaguucga guuuugagca cgagaugagu caggaggggu     1140

uuucggcggc cauaacgagu aaugggccgu uguugagcac gguggggagc uaugauuggg     1200

ccgggggggu guuuuuguau acgaguaaag agaagaguac cuuuauaaau augacgcgcg     1260

uggacagcga uaugaaugau gccuacuugg gguaugcggc cgccauaauc uugaggaauc     1320

gcguccagag cuugguccuc ggggcgccga gguaucagca uauaggguug gucgccaugu     1380

uuaggcagaa uacgggcaug ugggagucga augccaaugu gaaagggacg cagauagggg     1440

ccuauuuugg ggccagcuug uguagcgucg auguggauag caaugggucg accgacuugg     1500

ucuugauagg ggccccgcau uauuacgaac aaaccagggg ggggcagguc agcgugugcc     1560

cguugccgag ggggagggcg agguggcagu gugaugccgu cuuguacggg gagcaggggc     1620

agccgugggg gcgcuuuggg gcggccuuga cgguguuggg ggaugugaau ggggauaagu     1680

ugacggaugu cgccauaggg gccccggggg aagaggauaa uaggggggcc gucuauuugu     1740

uucaugggac gagugggucg gggauaagcc cgagucauag ccagaggauc gcggggagca     1800

aguuaagucc gcgcuuacag uauuuuggcc agucguugag uggggggcag gauuugacca     1860

uggauggguu ggucgacuua accgucgggg cccagggcca cgucuuguug uugaggaguc     1920

agccggucuu gagggugaaa gccauaaugg aauuuaaccc gagagaggug gccaggaaug     1980

uguuugagug uaaugaucag gucgugaaag ggaaggaggc gggggaggug cgcgucugcu     2040

uacaugucca gaaaucgacc agggacaggu uaagggaggg gcagauacaa agugucguga     2100

cguaugauuu ggcguuggau agugggcgcc cgcauucgag ggcgguguuu aaugagacga     2160

agaacagcac gaggagacag acgcaagucu ugggguugac gcagaccugu gaaaccuuga     2220

aguugcaguu accgaauugc auagaggauc cggugagccc gauagucuug agguugaacu     2280

ucaguuuggu ggggaccccg uugagcgccu uugggaauuu gaggccggug uuggcggagg     2340

augcgcagag guuguuuacg gcguuguuuc cguuugagaa aaauuguggg aaugauaaua     2400

ucugccagga ugauuugucg auaacguuua gcuuuaugag cuuggauugu uuggucgucg     2460

gggggccgag ggaguucaau gugaccguga cgguccgcaa ugauggggaa gacaguuauc     2520

gcacccaggu caccuuuuuu uuucccuugg auuugagcua uaggaaggug agcacguugc     2580

agaaucagag gagccagagg agcuggcgcu uggccugcga gagcgcgagc agcaccgagg     2640

ucucgggggc guuaaagagc acgaguugca guaucaauca uccgauauuu ccggaaaauu     2700

cggaggugac cuuuaauauc accuuugaug ucgauagcaa ggccagcuug gggaauaagu     2760

ugcucuuaaa ggcgaaugug acgucggaga auaauaugcc gcgcaccaau aagaccgaau     2820

uucaguugga guugccggug aaauacgcgg ucuauauggu ggugacgucg caugggguca     2880

guaccaagua uuugaauuuc acggcgucgg agaauaccag ucgcgucaug cagcaucagu     2940

aucaagucag uaauuugggg cagaggucgu ugccgauaag uuuggucuuu uuggucccgg     3000

ugcgcuugaa ucaaaccguc aucugggaua ggccgcaggu caccuuuagc gagaauuuga     3060

guaguaccug ccauaccaag gagagguugc cgucgcacag ugauuucuug gccgaauuga     3120

ggaaggcgcc ggucgucaau uguagcauag ccgucuguca aaggauccaa ugugauaucc     3180

cguuuuucgg cauccaagag gaauuuaaug ccaccuugaa ggggaauuug ucguuugauu     3240

gguacauaaa aacgagccac aaucauuugu ugaucgucag uaccgcggag auauuguuua     3300

augauucggu guuuacccuc uuaccggggc agggggccuu ugucaggagc caaaccgaga     3360

ccaaggucga gccguuugag gugcccaauc ccuugcccuu gauagugggg aguagugucg     3420

ggggcuuguu guuguuggcg uugauaaccg ccgccuuaua caaauugggg uuuuuuaaaa     3480

ggcaguauaa ggacaugaug agugaggggg ggcccccggg cgcggagccg caaugaggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  5863
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt10)

<400>  5863
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuuaguuuaa aaaccuugcc guucuuauug cucuugcacg      120

uccaaaucag uaaagcguuc ccggucagca gcaaggaaaa gaacaccaag accguccaag      180

auuauuuaga gaaauuuuau cagcucccgu cgaaucaaua ccaaagcacc cgcaaaaacg      240

ggaccaacgu cauagucgag aaauugaagg agaugcaaag guucuucggc cucaacguca      300

ccggcaaacc gaacgaagag accuuagaua ugaugaagaa accgaggugc ggggucccgg      360

auucgggggg guucaugcuc acgccgggga auccgaaaug ggagaggacc aaucucacgu      420

aucgcaucag gaauuacacg ccgcaauuaa gcgaagccga agucgagcgc gccauaaaag      480

acgcguucga guuguggucg gucgccagcc cguugauauu uacgcgcaua agccaagggg      540

aagccgacau aaauaucgcc uucuaucagc gcgaccaugg ggauaacagc ccguucgacg      600

ggccgaacgg gauauuggcc cacgcguucc aaccggggca ggggaucggg ggggacgccc      660

acuucgacgc ggaggagacc uggacgaaua cgagugccaa cuauaaucuc uucuuggucg      720

ccgcccacga guucgggcac agccucggcu uggcccauag uagcgauccg ggggcgcuca      780

uguacccgaa uuacgccuuu cgcgagacgu cgaauuauag cuugccgcag gacgauauag      840

acgggaucca agcgauauac ggguugagcu cgaauccgau acagccgacc gggccgucga      900

ccccgaagcc gugcgauccg ucgcucaccu ucgacgccau aacgaccuug aggggggaga      960

ucuuguuuuu caaggaucgc uauuuuuggc gccgccaccc gcaauugcag cgcguggaga     1020

ugaacuucau cagcuuguuu uggccgaguu ugccgaccgg gauccaagcc gccuacgagg     1080

acuucgaucg cgauuugauc uuuuuguuca aggggaauca guauugggcc uuaucggggu     1140

acgacaucuu acagggguac ccgaaagaca ucagcaauua cggguuuccg ucgucggugc     1200

aggccaucga ugccgccguc uuuuaucgcu cgaagaccua uuuuuucguc aacgaucagu     1260

uuuggcgcua cgacaaucag cgccaguuua uggaaccggg guacccgaag ucgaucagcg     1320

gggcguuccc ggggaucgaa ucgaaggucg acgccgucuu ucaacaggag cacuuuuuuc     1380

acguguuuuc ggggccgcgc uacuaugccu ucgacuugau cgcccaacgc gucacgcgcg     1440

ucgcccgcgg gaacaagugg uugaauugcc gcuacgggug aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  5864
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt10)

<400>  5864
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucguuauggc aaccuuuggu auugguauua uuggucuuag      120

ggugcugcuu cgcagcgccg cgucagcgac agucgacauu agucuuguuc ccgggugacu      180

uacgaaccaa cuuaacugau cggcaauuag cugaagagua uuuauacagg uacggcuaca      240

cgcgcguagc ggagaugagg ggggagucua agaguuuagg cccagcauua cucuuguugc      300

agaaacaguu aucguuaccc gaaacggggg aauuagacuc ggcgacacuc aaggcgaugc      360

gcacuccucg uugcggagua cccgacuugg gacgauuuca gacauucgag ggugauuuga      420

aguggcacca ccacaacaua acguacugga uccagaacua cucugaggac uuaccucgug      480

caguaauaga cgacgcuuuc gcacgagcgu ucgcuuuaug gucggccguu acacccuuga      540

cguuuacgcg agucuauucg cgcgacgccg acauaguaau acaguucggg guagccgagc      600

acggugacgg cuacccauuc gacgguaagg acgguuuauu agcgcacgcg uucccgccgg      660

ggccggguau ccagggcgac gcgcacuucg acgacgacga auuauggucu uuagggaaag      720

ggguaguugu accuacgcgu uucgguaacg cggacggugc cgcaugccau uucccguuca      780

uauucgaggg gcgaucauau agugcgugca cuacggacgg acggucggac ggguuacccu      840

gguguucgac uacugcgaac uacgacacgg acgaccgauu cgguuucugc ccgucggagc      900

guuuauacac gcaagacggu aacgcggacg gcaagccuug ccaguucccu uucauauucc      960

agggacaguc guacucggca ugcacaaccg acgggcgguc ggacggguac cgguggugcg     1020

cgacuacggc gaacuacgau cgcgacaagu uauucggguu cugcccaaca cgggcagacu     1080

cuaccguaau gggagggaac agugccggag aguugugcgu auuccccuuc acguucuugg     1140

gaaaagagua cucaacaugc acuucggaag gccgggguga cggucgauug uggugcgcca     1200

cuacgaguaa cuucgacucg gacaaaaagu gggguuucug uccugaccag ggcuauucgu     1260

uauucuuagu agcagcacac gaguucgggc acgcauuagg auuggaccac aguaguguac     1320

ccgaagcauu gauguauccg auguaccgau uuacggaagg uccgccguua cacaaggacg     1380

acguaaacgg uauccgacac uuauacggcc cacggccgga gccggaaccg cgcccaccga     1440

ccacaacgac uccacagccc acugcaccgc ccacaguaug uccuacgggu ccuccgacag     1500

uacacccguc ggagcgaccg acggcagguc ccacuggacc gccgagugca gggccgacgg     1560

ggccgccgac cgcagguccg ucgacggcga caacgguccc guuaucgccc guagacgacg     1620

cgugcaacgu uaacauauuc gacgcaauag cagagauagg uaaccaguua uacuuauuca     1680

aggacggcaa guacuggcgc uuuucggagg ggcgaggaag ucgaccccag gggccguucu     1740

uaaucgcgga caaguggccg gcauuaccuc gaaaguuaga uucaguauuc gaggagcgau     1800

uaaguaagaa auuauucuuc uucucgggua ggcaaguaug gguauauacg ggugccuccg     1860

uauuagggcc ccggaggcuc gacaaguugg ggcucggugc ugacgucgcg cagguaacgg     1920

gugcuuuacg cucgggucga ggaaagaugu uauuauucag uggucgccga uuauggcguu     1980

ucgacguaaa ggcacagaug gucgacccuc gaucggcguc ggaggucgac cguauguucc     2040

cggguguacc guuagacaca cacgacguau uccaguaccg cgaaaaggcu uacuucugcc     2100

aggauagguu cuacuggcga gucucgucga ggucggaauu aaaucaagua gaccagguag     2160

gguaugucac guacgacauc uuacagugcc cggaggacug aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  5865
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt10)

<400>  5865
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacccgggcg uguuagccgc guuuuuguuu cucucgugga      120

cccacugcag agcguuaccg uugccgucgg ggggggacga ggacgaccuc agcgaagagg      180

auuugcaauu cgccgaaagg uauuuacgca gcuauuauca cccgaccaac uuggccggga      240

uauuaaaaga aaacgccgcc ucgaguauga ccgaacgcuu gagggagaug caaaguuuuu      300

uugggcucga agucaccggg aaguuggaug acaauacgcu cgacgugaug aagaaaccgc      360

gcuguggcgu cccggacguc ggggaguaua acgucuuucc gaggaccuug aaguggagua      420

agaugaaccu cacguaucgc aucgucaacu auacgccgga caugacccac agcgaggugg      480

agaaagccuu uaagaaggcg uuuaaggucu ggagugacgu caccccguua aacuucacgc      540

gcuugcauga cgggaucgcc gauauaauga uuagcuucgg gaucaaagaa cacggggauu      600

uuuauccguu cgacggcccg agcggguuau uagcccacgc cuucccgccg ggcccgaacu      660

acggggggga cgcgcacuuc gacgacgacg agacguggac cucgucgagu aagggguaua      720

aucucuucuu ggucgccgcc cacgaauuug ggcauagucu cggguuggau cauaguaaag      780

auccgggggc cuugauguuc ccgauauaua cguauacggg gaagucgcau uucauguugc      840

cggacgauga cguccagggc auacaaaguu uguacgggcc gggggacgag gauccgaauc      900

cgaagcaccc gaagaccccg gauaagugcg auccgagucu caguuuggac gcgaucacgu      960

cguugagggg ggagaccaug auauucaagg aucgcuuuuu uuggagguua cacccgcaac     1020

aagucgacgc cgaauuauuc cucaccaaga gcuucuggcc ggaguugccg aauaggaucg     1080

acgccgccua cgaacauccg agccacgauu ugauauuuau auuucgcggg cgcaaguucu     1140

gggccuugaa cggguacgau aucuuagagg gguacccgaa gaagaucagc gaguuagggu     1200

ugccgaagga ggucaaaaaa aucucggccg ccguccauuu cgaagacacc gggaaaaccu     1260

uguuauuuag cgggaaucaa guguggcgcu acgacgacac caaucacauc auggacaagg     1320

auuacccccg cuugaucgag gaggauuuuc cggggaucgg ggacaagguc gacgccgugu     1380

acgaaaagaa cggguacaua uacuucuuua augggccgau ccaauucgag uauucgauau     1440

ggucgaauag gaucgucagg gugaugccgg ccaacaguau ccucuggugc ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  5866
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt10)

<400>  5866
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaccccga acaccaccga agauuacgac accacaaccg      120

aguucgacua cggcgacgcc acccccugcc aaaaagucaa cgaacgcgcc uucggcgccc      180

aacuccuccc accccuuuac ucccucgucu ucgucaucgg ccucgucggc aauauccucg      240

uaguccucgu ccucguccaa uacaaacgac ucaaaaacau gaccuccauc uacuuacuca      300

acuuagccau cuccgaccuc cucuuccucu ucacccuccc cuucuggaua gacuacaaac      360

ucaaagacga cugggucuuc ggcgacgcca ugugcaaaau ccucucgggc uucuacuaca      420

caggacucua cuccgaaauc uucuucauca uccucuuaac uaucgaccgc uaccuagcca      480

ucguccacgc cgucuucgca cuacgcgccc gcaccguaac cuucggcguc aucaccucaa      540

ucaucaucug ggcccucgcc auccucgccu ccaugcccgg ccucuacuuc ucaaaaaccc      600

aaugggaguu cacacaccac acaugcucac uccacuuccc ccacgaaucc uuacgcgaau      660

ggaaacucuu ccaagcccuc aaacucaacc uauucggccu aguccuccca cuacucguca      720

ugaucaucug cuacacaggc aucaucaaaa uacuccuccg ccgccccaac gaaaagaaau      780

ccaaagcagu ccgccucauc uuugucauaa ugauaaucuu cuuccuauuc uggacccccu      840

acaaccucac cauccucauc ucaguauucc aagacuuccu cuucacccau gaaugcgaac      900

aaucacgcca cuuagaccuc gccguccaag ucaccgaggu cauugccuac acccacugcu      960

gcgucaaccc aguaaucuac gccuucgucg gcgaacgcuu ccgcaaauac cuccgucaac     1020

uauuccaccg acgcgucgcc guacaccucg ucaaauggcu ccccuuccua ucugucgacc     1080

gauuagaacg cgucuccucc acaagcccaa gcaccggcga acacgaacuc uccgccggcu     1140

ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  5867
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt10)

<400>  5867
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgaacauuag caugcuuguu guuauuaggu ugcggguacu      120

uagcgcacgu guuagcagag gaggcagaga ucccgcguga gguuaucgag cgcuuggcac      180

gaucgcagau ccacaguauc cgagacuuac agcgguuguu ggagaucgac ucagucggcu      240

cggaggacuc guuagacacg aguuuacgag cgcacggggu gcacgccacg aagcacguac      300

cggagaagcg cccguugccg auacgucgca agcgaucgau cgaggaggcg gugcccgcgg      360

uuugcaagac gcgaaccguc aucuacgaga ucccacgauc gcagguagac ccuaccucgg      420

cuaacuucuu aauauggccu ccaugcguag aggucaagcg uugcacgggg ugcugcaaca      480

caucgucggu uaagugccag ccgucgcgag ugcaccaccg uucgguaaag guggccaagg      540

uugaguacgu acgaaagaag cccaagcuaa aggagguuca gguucgauug gaggagcacu      600

uagagugcgc uugcgccacg acgaguuuga accccgacua ccgugaggag gacacggggc      660

gaccgcgcga gucgggcaag aagcgaaagc gaaagcgguu gaagccgacg ugaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  5868
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt10)

<400>  5868
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaccguugcu gggcccuuuu cuugucguua ugcugcuacu      120

ugcgcuuggu gucggccgag ggugauccga uaccggagga gcuguacgag augcuaucug      180

accacaguau aaggucauuc gacgacuugc agcgauuauu acacggggac ccgggugaag      240

aggacggggc ggaguuagac uuaaacauga cgcgcucgca cucggguggg gaguuggagu      300

cguuagcgcg ggggcggcga ucguuagggu cguugacgau cgcggagccu gcgaugaucg      360

cggagugcaa gacgcguacg gaggucuucg agauaucgcg acguuuaauc gaccgaacca      420

acgcaaacuu cuuaguaugg cccccuugcg ucgagguaca gaggugcagu ggaugcugca      480

acaaccgaaa cguccagugc aggccgacgc agguucaguu gcguccggua caaguccgua      540

agaucgagau cguccguaag aagccgauau ucaagaaggc uacgguaacc uuagaggacc      600

aucucgccug caagugcgag acugucgccg cggcgaggcc gguaacucgg ucgcccggug      660

ggagucagga gcagcgugcg aagacgccgc agacgcgagu uaccauaagg accguacgug      720

ugcgucgucc gccgaaagga aagcaccgaa aguucaagca cacgcacgac aagacugccu      780

uaaaggagac guuaggugcc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  5869
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt10)

<400>  5869
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucguuauucg gcuuguuauu auugacgagu gcguuagcag      120

ggcagcggca agguacacag gcagagucga accucucguc gaaguuccag uucucgucga      180

acaaggagca gaacggugug caggacccac agcacgagcg uaucaucacg guuucgacaa      240

acgggucgau acacucgccg cguuucccac acacguaccc gcgaaacacu guguuagucu      300

ggcgucucgu ugccgucgag gagaacguuu ggauccaguu aacuuucgac gagagguucg      360

guuuagagga cccggaggac gacaucugca aguacgacuu cguugaggua gaggagccuu      420

cagacgguac gaucuuggga cgauggugcg ggucggggac cguucccggg aagcagauau      480

cgaaggggaa ccagauacga auccgauucg ucucggacga guacuucccg ucggagccgg      540

guuucugcau acacuacaac auaguaaugc cgcaguucac ggaggccguu ucgccgucug      600

ucuuaccgcc cucggcguua ccguuagacu uacucaacaa cgcgaucacg gcguucucua      660

cguuagagga cuuaauacgu uacuuagagc cggagcgaug gcaauuagac uuggaggacu      720

uguaccgccc caccuggcag uuacucggua aggcauucgu auucgggcga aagagucgag      780

uaguagacuu aaauuuauua accgaggagg uucgacuaua cucuugcacu ccccgcaacu      840

ucucgguuuc gauccgagag gagcuuaagc gcacggacac gauauucugg ccggggugcu      900

uauuggucaa gaggugcggg gguaacugcg cgugcugccu ucacaacugc aacgagugcc      960

agugcgugcc gucgaagguc acaaagaagu accacgaggu cuuacaacuu cgccccaaga     1020

cgggcgugcg agguuuacac aagagucuaa cugacguagc gcucgagcac cacgaggagu     1080

gcgacugcgu cugcaggggg ucgaccgggg ggugaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  5870
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt10)

<400>  5870
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgacuaa ucuucguaua caccuugaua ugcgccaacu      120

ucugcuccug ccgagacacg ucggccacuc cccagucggc uaguauaaag gcccuucgua      180

acgcgaacuu gcgucgggac gaccuuuaca ggagggacga gacuauccag gucaagggca      240

acggauacgu ccaaucgccc cgguucccca acaguuaccc gcggaacuua cuuuugaccu      300

ggcguuuaca cucgcaggag aacacgagga uccaauuagu uuucgacaac caguucggcc      360

ucgaggaggc cgagaacgac auaugccgau acgacuucgu agagguagag gacaucagug      420

agaccucgac gauaaucagg gggcgguggu gcggccacaa ggagguaccc ccucgaauca      480

agagucgaac caaccagauc aagauaaccu ucaagucgga cgacuacuuc guagcaaagc      540

cgggguucaa gauauacuac ucgcucuuag aggacuucca gccggcggcc gcgucggaga      600

caaacuggga gucgguaacg ucgucgauau cggguguguc guacaacuca cccucgguca      660

ccgacccgac cuugauagcc gacgcguuag acaagaagau cgccgaguuc gacacgguag      720

aggacuuguu gaaguacuuc aacccggagu cguggcagga ggacuuagag aacauguacu      780

uagacacgcc gagguacagg gggcggucgu accacgaccg caagucgaag guggacuuag      840

accgacuuaa cgacgacgcg aagcgauacu cgugcacacc ucgaaacuac aguguaaaca      900

ucagggagga guuaaaguua gccaacgucg uauucuuccc gcggugcuua uuaguucagc      960

guugcggggg caacugcggu ugcgggacgg ugaacuggcg aucuugcacg ugcaacucgg     1020

guaagaccgu aaagaaguac cacgaggucc uucaguucga gcccgggcac auaaagcguc     1080

gcggccgugc gaagaccaug gcgcucgugg acauucaacu cgaccaccac gagcguugcg     1140

acugcaucug cucgucgcga ccuccgcguu gaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  5871
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt10)

<400>  5871
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaacgcacu cgaaguuccc ggcggcgggu augaguaggc      120

cguuagacac aucgcuucgu uuaaagacau ucucgucgaa gagugaauac cagcucguug      180

ucaacgcggu ccggaaguug caagaaucag guuucuauug gucggcggua acgggggggg      240

aggcaaauuu auuauugucg gcggagccag cggggacauu cuuaauccgu gacucgucug      300

accagcggca cuuuuuuaca uuaucaguga agacacaauc ggguacgaag aaccuucgaa      360

uacagugcga gggcggaagu uucucguugc agagugaccc gcgaucuaca cagccggucc      420

cucgauucga cugcguauua aaguugguuc accauuacau gcccccaccg ggggcuccga      480

guuucccguc accgccgacg gagccgaguu cggagguacc ggagcagcca ucggcgcagc      540

cuuuaccggg uucgccgccu cgacgcgcgu acuacauaua cucggggggu gaaaagauuc      600

cacucguauu aucgaggccu uuaucgucga acguagcgac acuccaacac uugugccgca      660

agaccguuaa cggacauuua gacucguacg agaaggucac gcaacuccca ggcccgauca      720

gggaguucuu ggaccaguac gacgcuccau uaugaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  5872
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt10)

<400>  5872
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugccgagcg ccgggcaauu ggcguuauuu gccuuaggga      120

ucguccucgc cgccugucaa gcgcucgaaa auucgaccag ucccuuaucg gccgaucccc      180

cggucgccgc cgccgucguc agucacuuca acgauugucc ggacagucau acccaauuuu      240

guuuucacgg gacgugucgc uuccucgucc aagaagauaa accggccugc gugugucaca      300

gcggcuaugu cggggccagg ugcgaacacg ccgauuuguu agcggucguc gccgcgucgc      360

aaaaaaaaca agcgauaacg gcgcucgucg ucgugaguau agucgcguua gccguguuga      420

uaauaaccug cgucuuaauc cauuguuguc aagugaggaa gcauugcgaa ugguguagag      480

cguugauaug uagacaugaa aaaccgucgg cguuguuaaa agggcgcacg gccuguuguc      540

auagcgagac cgucguguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  5873
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt10)

<400>  5873
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccccgucug guuuacgauu auuacccuua uuguuacccu      120

uauugugguu auuaguauug acccccgggc gaccggccgc cggcuuaagu acgugcaaga      180

ccaucgacau ggaguuagua aagcggaagc gaauagaggc gauacgaggg cagaucuuau      240

cgaaguuacg auuagccagu ccgcccucgc agggcgaggu accgcccggg cccuugcccg      300

aggccguauu agcguuauac aacaguaccc gagaccgagu agcgggugag ucugcggagc      360

ccgagcccga gcccgaggcc gacuacuacg ccaaggaggu aacacgagua uugaugguag      420

agacccacaa cgagaucuac gacaaguuca agcagaguac gcacucuauc uacauguucu      480

ucaacacgag ugaguuacga gaggcgguuc ccgagcccgu auuauuaagu cgagcggagu      540

uacgauuauu gcgauuaaag uuaaagguag agcagcacgu agaguuauac cagaaguaca      600

guaacaacuc uuggcgauac uuaucaaacc guuuauuagc gccgucugac agucccgagu      660

gguuaucuuu cgacguaacg gggguaguac gacagugguu aagucguggg ggcgagauag      720

agggguuccg auugucagcg cacugcaguu gcgacucucg ggacaacacg uugcagguag      780

acaucaacgg cuucacgacg gggcgacgag gcgacuuagc caccauacac ggcaugaacc      840

gacccuucuu auuauuaaug gccacgcccu uagagcgugc gcagcacuua cagucuaguc      900

gacaccgacg agccuuagac accaacuacu gcuucaguuc gaccgagaag aacugcugcg      960

uacgacaguu auacaucgac uuccgaaagg acuuagggug gaaguggaua cacgagccga     1020

agggcuacca cgcgaacuuc ugcuuagggc ccugccccua caucuggucg uuagacacgc     1080

aguacaguaa gguauuagcc uuauacaacc agcacaaccc cggcgccucg gcggccccgu     1140

gcugcguacc gcaggcguug gagcccuuac ccauaguaua cuacguaggc cguaagccga     1200

agguagagca guuaaguaac augauaguac gaucgugcaa gugcaguuga ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  5874
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt10)

<400>  5874
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uauuaucugc guucuugaua uuacacuuag      120

uuaccguggc auugaguuua uccacuugca guacguuaga cauggaccag uucaugcgaa      180

agcgaauaga ggcuauaagg ggucagauuu ugucgaagcu caaguuaacg ucuccuccgg      240

aggacuaccc cgagccggaa gagguaccgc cggagguaau caguauauac aacucgacgc      300

gagaccuuuu acaggaaaag gcaucgcgac gcgcagcggc gugcgagagg gagcguucgg      360

acgaggagua cuacgcgaag gaaguauaca agaucgacau gccuccguuc uucccgucgg      420

agaacgcgau cccaccuacg uucuaucgac cguacuuccg caucgucagg uucgacguaa      480

gugcgaugga gaagaacgcc ucuaacuuag uaaaggcgga guuucgagua uucagguuac      540

agaacccgaa ggcgcgaguu cccgagcaga ggaucgaguu auaccagauc uuaaagagua      600

aggaccuuac uucgccuacg caacgauaca uagacaguaa gguaguaaag acgcgagccg      660

agggagagug guuaucguuc gacgucacgg acgcggucca cgagugguua caccacaagg      720

accgcaaccu uggcuucaag aucagucucc acugcccgug cugcacauuc gucccuucga      780

acaacuauau aauaccgaac aagucggagg aguuagaggc ucguuucgcg ggaaucgacg      840

ggacgucgac guacacgucg ggagaccaga agacgaucaa gucgacgcga aagaagaacu      900

cgggaaagac accgcacuug uuauuaaugu uguuaccguc guacagguua gagucgcagc      960

agacgaaccg ccgaaagaag cgagcgcuag acgcagcgua cuguuuccga aacguacaag     1020

acaacugcug uuuaaggccc uuauacaucg acuucaagcg cgacuugggu uggaagugga     1080

uccacgagcc uaaggguuau aacgcaaacu ucugcgcagg cgcgugcccc uaccucuggu     1140

cgucggacac ccaacacagu cgaguguuau cucuuuacaa cacgaucaac cccgaggcga     1200

gugccucgcc gugcugcguc ucgcaggacu uggagccauu aacgaucuug uacuacaucg     1260

guaagacgcc uaagaucgag caguuaucga acaugauagu caaaaguugc aagugcucau     1320

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  5875
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt10)

<400>  5875
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacu ugcagagggc guugguagua uuagcguuau      120

ugaacuucgc gacgguaucg uuaaguuuau cgacaugcac gacguuggac uucggccaca      180

ucaagaagaa gcgcguagag gcgauacggg gucagauauu aaguaaguua cgcuugacgu      240

cgccgccgga gccgacggua augacacacg uaccguacca gguauuagcg uuauacaaca      300

guacgaggga guuguuagag gagaugcacg gugagcgcga ggaggguugc acgcaggaga      360

acacggaguc ggaguacuac gcgaaggaga uacacaaguu cgacaugaua caggguuuag      420

cggagcacaa cgaguuggcg guaugcccca aggggauaac gaguaagguc uucagguuca      480

acguaucgag uguagagaag aaccgcacga acuuauucag ggcggaguuc cgaguauuaa      540

gggucccgaa cccgucgagu aagcgaaacg agcagaggau agaguuauuc cagauauuac      600

gccccgacga gcacauagcg aagcagcggu acauaggggg uaagaacuua cccacgcgcg      660

guacggcuga gugguugucg uucgacguaa cagacacggu aagggagugg uuauuacgca      720

gggagaguaa cuugggcuua gagauaucga uacacugccc uugccacacg uuccagccga      780

acggggacau auuagagaac auacacgagg uaauggagau aaaguucaag gguguagaca      840

acgaggacga ccacgggcga ggggacuugg ggagguuaaa gaagcagaag gaccaccaca      900

acccccacuu aauauugaug augauaccgc cgcaccgauu agacaacccc ggucaggggg      960

ggcagcgaaa gaagagggcg uuagacacga acuacugcuu ccgaaacuug gaggagaacu     1020

gcugcguaag gccguuauac auagacuucc gccaggacuu aggguggaag uggguacacg     1080

agccgaaggg uuacuacgcu aacuucugca gugguccgug ccccuacuug aggucggcag     1140

acacaacgca caguacggua uuagguuuau acaacacguu gaacccggag gcgucggcua     1200

guccgugcug cguaccgcag gacuuagagc ccuuaacaau auuguacuac guagggagaa     1260

cgccgaaggu agagcaguua ucgaacaugg uaguaaaguc gugcaagugc aguugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  5876
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt10)

<400>  5876
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccccggugg cggucugggc ggcuuuagcg guagggcuug      120

agcuuugggc ggccgcgcac gcguuaccgg cgcaggucgc guucacgccc uacgcucccg      180

agccggguuc aacgugcagg uugcgcgagu acuacgacca aacugcgcag augugcugcu      240

cgaagugcuc cccgggacag cacgcgaagg uauucugcac caaaacauca gacacggugu      300

gcgacucgug cgaggacucg acuuacacgc aauuauggaa cugggugccc gagugccucu      360

cgugcggauc gcgaugcucg ucagaccaag uagagaccca ggccugcacg cgcgagcaaa      420

accggaucug cacgugccgc ccgggcuggu acugcgccuu gucgaagcag gaggguugcc      480

gacucugcgc gccccuccga aagugccggc cggguuucgg gguagcgcga ccugggacgg      540

agacgucgga cguagucugc aagccgugcg cgcccggaac auucucuaac acgacaucgu      600

cuaccgacau cugccgcccg caccagaucu gcaacgucgu ugcaaucccg gggaacgcga      660

guauggacgc gguaugcaca ucgacgucgc cgacgcgcuc aauggcgccg ggcgccgugc      720

accuuccgca gcccguaucg acgcggucgc agcacaccca accgacgccg gagccgucga      780

ccgcgccguc gacuucguuc cuuuuaccca uggggcccuc gccgcccgcg gagggcucga      840

ccggugacuu cgcguugccg guaggguuaa ucgugggcgu cacggcguua ggguuguuaa      900

ucaucggcgu cguaaacugc gugauaauga cgcagguaaa gaagaagccg cugugcuugc      960

agcgagaggc gaaggugccg cacuuaccgg ccgacaaggc ccguggcacg cagggucccg     1020

agcagcagca cuuauuaauu accgcgccgu cgucgaguuc gaguucguug gagucgagcg     1080

caucggcccu agacaggcga gcccccacgc gaaaccagcc gcaggcgccg gguguggagg     1140

cgucuggggc cggcgaggcc cgugccucga ccggaucguc ggacucgucg ccgggcggac     1200

acgguacaca gguaaacgua acuugcaucg uuaacguaug cucgucgucg gaccacucga     1260

gucagugcuc gagucaggcg ucgucgacga ugggggacac ugacucgucg cccucagaga     1320

guccuaagga cgagcagguc ccguucucga aggaggagug cgccuuccgu agucaacucg     1380

agacaccgga gacgcuccuc ggaucaacgg aggagaagcc guuacccuua ggcguuccgg     1440

acgcggggau gaagccgucg ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  5877
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt10)

<400>  5877
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccguaaugc gcuuauuucc auguuucuug caguuauuag      120

cgggcuuggc cuuacccgca guaccaccgc aacaaugggc ucucucggca gggaacggua      180

guucggaagu ugaggucguc ccguuccagg aggucugggg ucgaaguuac ugcagggccc      240

uugagcgccu cguggacgua guaagugagu auccgaguga gguagagcau auguucucgc      300

cuaguugcgu uucuuuauug agguguacag guugcugcgg ugacgagaac uuacacugcg      360

uacccguaga gaccgccaac guaacuaugc aauuauugaa gauucgaucg ggagaccguc      420

caucguacgu agaguuaacc uuuagucagc auguccguug cgagugccgu ccgcuucgcg      480

agaaaaugaa gcccgagcgu cgaaggccua aagggcgcgg gaagcggcgc agggagaaac      540

agcgaccuac ggacugucac uugugcgggg acgcgguccc gcgacgcuga ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  5878
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt10)

<400>  5878
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgaccgcc agaccgacac ggcccccucg ccguccuacc      120

accucuuacc cggccggcgc cggaccgugg acgccgcggc cucgcgcggg cagggccccg      180

agcccgcccc cgggggcggg gucgagggcg ugggcgcccg cgggguggcc uuaaaguuau      240

ucguccagcu cuuaggcugc ucccgguucg ggggcgcggu ggugcgggcc ggggaggccg      300

agcccucggg cgccgcgcgc uccgccucgu ccggccggga ggagccccag cccgaggagg      360

gggaggagga ggaggagaag gaggaggagc gcggcccgca guggcgguua ggggcccgca      420

agcccggcuc guggaccggc gaggccgccg ucugcgcgga cuccgccccc gccgcccggg      480

ccccgcaggc gcucgcccgc gccucggggc ggggcgggcg cguggcccgg cgcggcgccg      540

aggaguccgg gccgccccac ucgcccuccc ggcgcggcuc ggcgucccgg gccggccccg      600

ggcgcgccuc ggagaccaug aacuucuuau uauccugggu gcacuggucg cucgccuuau      660

uacucuacuu acaccacgcc aagugguccc aggcggcccc gauggccgag ggcgggggcc      720

agaaccacca cgaggucgug aaguucaugg acguguacca gcgcucguac ugccacccca      780

ucgagacguu agucgacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      840

ccucgugcgu gccgcucaug cggugcgggg gcugcugcaa cgacgagggc uuagagugcg      900

ugcccaccga ggaguccaac aucaccaugc agaucaugcg caucaagccc caccaggggc      960

agcacaucgg cgagaugucg uucuuacagc acaacaagug cgagugccgg cccaagaagg     1020

accgcgcccg gcaggagaag aaguccgucc gcgggaaggg caaggggcag aagcggaagc     1080

gcaagaaguc ccgguacaag ucguggucgg uguacguggg cgcgcgcugc ugccucaugc     1140

cgugguccuu acccggcccc caccccugcg ggccgugcuc ggagcggcgc aagcacuuau     1200

ucguccagga cccgcagacg ugcaagugcu cgugcaagaa cacggacucg cggugcaagg     1260

cgcgccagcu cgaguuaaac gagcggacgu gccgcugcga caagccgcgg cgcugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  5879
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt10)

<400>  5879
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuucuuau ugucgugggu ccacuggagu uuagcguuau      120

uguuauacuu acaccacgcg aaguggucgc aagcagcgcc gauggcggag gggggugguc      180

aaaaccacca cgagguagua aaguucaugg acguguacca gaggucguac ugccacccga      240

uagagacguu gguagacaua uuccaagagu acccggacga gaucgaguac aucuucaagc      300

cgucgugcgu accguuaaug cgcugcggug guugcugcaa cgacgagggu uuagagugcg      360

ucccuacgga ggagaguaac aucacuaugc agauaaugag gauuaagccg caucaagggc      420

agcacauagg ggagaugucg uucuugcagc auaacaagug cgagugccga ccgaagaagg      480

accgagcgcg acaggagaag aagaguguaa gggguaaagg gaagggucaa aagcgcaaga      540

ggaaaaagag ucgauacaag ucguggucgg uauacgucgg ggccaggugc ugcuuaaugc      600

cguggucguu accagggccg cacccgugcg ggccgugcuc ggagcgcagg aagcacuuau      660

ucguacagga cccacagacg ugcaagugca guugcaagaa cacggacucg cguugcaagg      720

cacgacaguu agaguuaaac gagcgaacgu gccggugcga caagccucga aggugaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  5880
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt10)

<400>  5880
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucgccguuau ugaggagguu auuauuggcg gccuuguuac      120

aauuagcgcc ggcgcaagcg ccggugaguc aaccggacgc gccggggcau caacgcaagg      180

ucgucagcug gaucgacguc uacaccaggg ccacguguca accgagagaa gucgucgucc      240

cgcucaccgu cgaauugaug gggacggucg cgaagcaauu agucccgucg ugugucaccg      300

uccaaaggug cggggggugu uguccggaug acggguuaga augcgucccg accggccaac      360

aucaggugag aaugcaaaua uugaugauaa gauaucccuc gucgcaauua ggcgaaauga      420

guuuagagga gcauucgcaa ugcgaguguc gcccgaagaa gaaagauucg gccgucaaac      480

cggaucgcgc cgcgaccccg caucauaggc cgcaaccgag gagcgucccc gggugggaua      540

gcgcgccggg ggccccgagu ccggccgaua uaacgcaccc gaccccggcg ccggggccga      600

gcgcgcaugc cgccccgucg acgacgucgg cguuaacgcc ggggccggcg gccgcggccg      660

cggaugcggc cgccaguagu gucgcgaaag ggggcgccug aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  5881
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt10)

<400>  5881
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccucuuag gguucuucag cgucgccugc uccuuacugg      120

cggcggcccu ccugcccggg ccgcgcgagg ccccggcggc ggcggcggcg uucgagagcg      180

gccuggaccu cuccgacgcc gagccggacg cgggggaggc gaccgccuac gccucgaagg      240

acuuagagga gcagcugcgg uccgucagcu ccguggacga gcucaugacc gugcuguacc      300

ccgaguacug gaagauguac aagugccagu ugcgcaaggg cggguggcag cacaaccggg      360

agcaggcgaa ccucaacagc cgcacggagg agaccaucaa guucgcggcc gcccacuaca      420

acaccgagau ccucaagucc aucgacaacg aguggcggaa gacccagugc augccgcgcg      480

aagucugcau cgacgucggc aaagaguucg gcguggccac gaauacguuu uucaagccgc      540

ccugcgucag uguguaucgg ugcgggggcu guuguaacuc cgaaggguua caauguauga      600

auacgucgac cucguauuua ucgaaaacgc uguucgagau caccgucccc uugucccagg      660

ggccgaagcc cgucaccaua ucguucgcga accauaccuc gugucgcugu augagcaagu      720

uagacgugua ucgccaggug cacucgauca uccggcggag uuuacccgcg acguugcccc      780

aaugccaagc cgccaauaaa acguguccga cgaacuauau guggaacaac cauauauguc      840

gcuguuuagc ccaagaggac uucauguuca guuccgacgc cggggacgau agcaccgacg      900

gcuuucacga uauaugcggc cccaauaaag aauuagacga ggaaacgugc caaugcgucu      960

gucgggcggg guugcgcccc gcgucgugcg gcccgcauaa ggagcucgau cggaauagcu     1020

gucaaugcgu gugcaagaau aaguuguuuc cgucgcagug cggggcgaau cgcgaguucg     1080

acgagaauac gugucaaugc gugugcaagc ggacgugucc gcgcaaccag ccguugaacc     1140

ccggcaagug cgcgugcgag ugcaccgagu cgccgcaaaa gugucuccug aagggcaaga     1200

aauuucauca ucagaccugu ucgugcuauc ggcgccccug caccaaucgg caaaaagccu     1260

gcgaacccgg guucagcuac uccgaggagg ucugccgcug cgugcccagc uacuggaagc     1320

gcccgcagau gucgugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  5882
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt10)

<400>  5882
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagggaau gggucguagu caacgucuuc augauguuau      120

acguacaauu aguacaaggu ucgucgaacg agcacggucc ggucaagcgu ucgucgcaau      180

cgacguuaga gcguucggag cagcagauac gagcggcguc gucguuagag gaguugcuac      240

ggauaacgca cucggaggac uggaaguuau ggcgaugucg auuacgcuua aagucguuca      300

caucgaugga cucgaggucg gcuucgcacc gcucgacgcg guucgccgcg acauucuacg      360

acauagagac guuaaagguc aucgacgagg aguggcagcg cacgcagugc ucgccgaggg      420

agacuugcgu cgaggucgcg ucagaauugg guaagucgac uaacacguuu uucaagccuc      480

cgugcguuaa cgucuuccgu ugcggggguu gcugcaacga ggagucguua aucugcauga      540

acacaaguac gucauacauc ucgaagcaau uauucgagau cucgguccca uuaaccucgg      600

ucccggaguu ggugccggua aagguagcga accacacggg gugcaagugc uuaccgacgg      660

cuccgcgaca cccguacagu auaauacgac ggucgauaca gauucccgag gaggaccgau      720

gcagucacuc gaagaagcua ugcccaaucg acaugcucug ggacaguaac aagugcaagu      780

gcguauuaca ggaggagaac cccuuggcgg ggacggagga ccacucgcac uugcaggagc      840

cggcguugug cggaccgcac augauguucg acgaggaccg gugcgagugc guaugcaaga      900

cuccgugccc gaaggacuug auucagcacc cuaagaacug cucgugcuuc gaaugcaagg      960

agucguuaga gacgugcugc cagaagcaca aguuguucca cccggauaca ugcaguugcg     1020

aggaccgaug cccguuccac acacgacccu gcgcgucggg uaagacggcu ugcgcgaagc     1080

acugccgauu cccuaaggag aagcgagcgg cacagggucc gcacucucgu aagaacccgu     1140

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  5883
<211>  924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002119.1__HsHMGB1 (opt10)

<400>  5883
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gguaaaggug acccgaaaaa gccacgcggu aagaugaguu      120

cguaugcguu cuucguccaa acgugccgag aggaacacaa gaaaaagcac ccggacgcgu      180

cgguaaacuu cucggaguuc ucaaaaaagu gcuccgaacg cuggaagacg augucggcga      240

aagagaaagg uaaauuugaa gauauggcga aagcggacaa ggcgcgcuac gagagggaga      300

ugaagacaua uauaccgccg aagggugaga ccaagaaaaa guucaaggac ccgaacgcgc      360

cgaagcggcc gccgucugcg uuuuuccuuu ucuguucgga guaccgcccg aagauaaagg      420

gagagcaccc gggccuuucg auaggcgacg uagcgaaaaa guugggugaa auguggaaua      480

acacggcggc ggacgauaaa cagccauaug aaaagaaagc agcgaagcuc aaggaaaagu      540

acgagaaaga uaucgcggca uaucgagcaa aagguaaacc ggacgcggcg aagaaaggug      600

uaguaaaagc agaaaagucg aagaaaaaga aagaggaaga ggaagaugaa gaggacgagg      660

aagaugaaga ggaagaggaa gaugaagagg acgaggacga ggaagaggac gaugacgaug      720

aaugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      780

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      900

gcucuuuuca gagccaccag aauu                                             924


<210>  5884
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  5884
auggucgccg gcacccguug ccuccuugcc cuccuccuac cccaaguccu acuaggcgga       60

gcagccggcc ucguccccga acucggccgc cgcaaauucg ccgccgccuc auccggacgc      120

cccuccucac aacccagcga cgaaguacuc ucagaauuug aacuucgucu acucuccaug      180

uucggccuca aacaacgacc cacucccucc cgcgacgcag ucgucccccc uuacaugcua      240

gaccuuuacc gccgccacuc cggccaaccc ggaucacccg cccccgacca ucgccucgaa      300

agagccgccu cccgagccaa uaccguccgc ucauuccacc acgaagaauc acucgaagaa      360

cuacccgaaa ccagcggaaa aacaacacgc agauucuucu ucaaccucuc cagcaucccc      420

accgaagaau uuaucaccuc cgccgaacua caaguauuca gagaacaaau gcaggacgcc      480

cucggcaaca acuccagcuu ccaccaccgc aucaacauau acgaaauaau caaacccgcc      540

acagcuaacu ccaaguuccc cgucacacgc cuacucgaca cccgccuagu caaccaaaau      600

gccucccgcu gggaauccuu cgacgucacc cccgccguca ugcgauggac cgcacaaggc      660

cacgccaauc acggcuucgu cguagaaguu gcacaccuag aagaaaaaca aggcgucucc      720

aaacgccacg uccgcaucuc cagaucccua caccaagacg aacacucaug gucccaaauc      780

cgcccccucc uagucaccuu cggacaugac ggcaaaggac acccgcucca caaacgcgaa      840

aaacgccaag ccaaacacaa acaacgcaaa cgccucaaau cauccugcaa acgccaccca      900

cucuacguag acuucuccga cguaggaugg aacgacugga uagucgcacc cccaggcuac      960

cacgcauucu acugccacgg agaaugccca uucccacuug ccgaccaccu caacuccacc     1020

aaccacgcua ucguacaaac acucgucaac uccgucaacu caaaaauccc aaaagcaugc     1080

ugcgucccca cagaacucuc agccaucucc augcucuacc ucgacgaaaa cgaaaagguc     1140

guccuaaaaa acuaccaaga cauggucguc gaaggcugcg gcugccgcua g              1191


<210>  5885
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  5885
augcacgucc gaucacuacg cgccgcagcc ccacacuccu ucguagcacu cugggcaccc       60

cuauucuuac uccgcuccgc acuagccgac uucucccucg acaacgaagu ccacucgagc      120

uucauccacc gccgccuacg gucccaagaa agacgcgaaa ugcaacgcga aauccucuca      180

auucuaggac ucccccaccg cccccgcccc caccuccaag gcaaacacaa cucugccccc      240

auguucaugc ucgaccucua caacgccaug gcaguagaag aaggaggcgg acccggcggc      300

caaggcuucu cauaccccua caaagccguu uucucaaccc aaggcccgcc ccucgcaucc      360

cuccaagacu cacacuuccu aaccgacgcc gacaugguaa ugucauucgu caaccucgua      420

gaacaugaca aagaauuuuu ccacccccgc uaucaccacc gcgaauuucg auucgaccuc      480

ucgaaaauac ccgaaggcga agccgugacc gcagccgaau uucgcauaua caaagacuac      540

auccgcgaac gcuucgacaa cgaaacauuc cgcaucuccg ucuaccaagu gcuccaagaa      600

caccucggcc gcgaaagcga ccucuuccua cuugacuccc gcacacuuug ggccucugaa      660

gaagguuggc ucguauucga cauaacagcc accucaaacc acuggguagu caacccccgu      720

cacaaccuag gacuccagcu aucaguagaa acacucgacg gccagagcau caaccccaaa      780

cuugcgggac ucaucggccg ccacggacca caaaacaagc agcccuucau ggucgccuuc      840

uuuaaagcca ccgaaguaca uuucagaucc auacgcucca ccggguccaa acaacgauca      900

caaaaccgau ccaaaacccc aaaaaaccaa gaagcucuac gaauggcaaa cguagcugaa      960

aacagcuccu cagaccaacg ccaagccugc aaaaaacacg aacucuacgu cuccuuccga     1020

gaccucggcu ggcaagacug gaucaucgcc ccagaaggcu acgcagcaua cuacugcgaa     1080

ggcgaaugcg ccuucccccu uaacucuuac augaacgcca ccaaccacgc aaucguccag     1140

acccucguac acuucaucaa ccccgaaacu guccccaaac ccugcugcgc ccccacccaa     1200

uuaaacgcaa ucuccguccu cuacuucgac gacuccucga acgucauacu caaaaaauac     1260

cgaaacaugg ucguccgcgc cugcggcugc cauuaa                               1296


<210>  5886
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  5886
augaaagccu ccgccgcccu ccucugccuc cuccucaccg ccgccgccuu cuccccccaa       60

ggccuagccc aacccgucgg caucaacacc uccaccaccu guugcuaccg auucaucaac      120

aaaaaaaucc ccaaacaacg ccucgaaucc uaccgccgca ccaccuccuc acacugcccc      180

cgcgaagccg ucaucuucaa aaccaaacuc gacaaagaaa ucugcgccga ccccacccaa      240

aaaugggucc aagacuucau gaaacaccuc gacaaaaaaa cccaaacccc caaacucuaa      300


<210>  5887
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  5887
augcacaaau ggauccucac cuggauccuc cccacccucc ucuaccgcuc cugcuuccac       60

aucaucugcc ucgucggcac caucucccuc gccugcaacg acaugacccc cgaacaaaug      120

gccacaaacg ucaacugcuc cucccccgaa cgccacaccc gcuccuacga cuacauggaa      180

ggcggcgaca uccgcguccg ccgacucuuc ugccgcaccc aaugguaccu acgcaucgac      240

aaacgcggca aaguaaaagg cacccaagaa augaaaaaca acuacaacau cauggaaauc      300

cgcacagucg ccgucggcau agucgcaauc aaaggcgucg aauccgaauu uuaccucgcc      360

augaacaaag aaggcaaacu cuacgccaaa aaagaaugca acgaagacug caacuucaaa      420

gaacucaucc ucgaaaacca cuacaacacc uacgccuccg ccaaauggac ccacaacggc      480

ggcgaaaugu ucgucgcccu caaccaaaaa ggcauccccg uccgcggcaa aaaaaccaaa      540

aaagaacaaa aaaccgccca cuuccucccc auggccauca ccuaa                      585


<210>  5888
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__P48741__HsHSPA7

<400>  5888
augcaagccc cccgcgaacu agccguaggc aucgaccucg gcacaaccua cagcuguguc       60

ggcguauucc aacaaggcag aguagaaauc cuagccaacg accaaggcaa cagaacgacc      120

ccaucauacg ucgcguucac cgacacagaa aggcuaguag gagacgcagc aaaaucccaa      180

gcagcccuaa acccgcacaa cacuguauuc gacgccaaac gccuaaucgg acgaaaauuc      240

gcagacacaa ccguccaauc agacaugaaa cacuggccau uccaagucgu cuccgaaggu      300

ggaaaaccca aaguacgagu augcuaccga ggggaagaca aaacauucua cccagaagaa      360

auaagcucaa ugguacuaag caaaaugaaa gaaaccgcgg aagccuaccu aggccaacca      420

guaaaacacg ccguaaucac ggucccgacc uacuucagca acucccagag acaggccacc      480

aaagacgcag gagcaaucgc aggccuaaaa guacucccaa ucauaaacga agccacagcc      540

gcagcaauag ccuacggccu ggaccgaaga ggagccggca aacgaaacgu acucauauuc      600

gaccuaggag gaggaacauu cgacguaucc guacucucga ucgacgccgg ggucuucgaa      660

guaaaagcua ccgccggcga cacccaccua ggaggcgaag acuucgacaa ccgccuaguc      720

aaccacuuca uggaagaauu ucgcagaaaa cacggcaaag accuaagcgg aaacaaacga      780

gcccucagac gacuccgaac agccugcgaa cgagccaaac gcaccccauc aagcagcacc      840

caggccacac uagaaaucga cucccuauuc gaaggcguag acuucuacaa aagcaucacc      900

agagccagau ucgaagaacu cugcagcgac cuauuccgaa gcacccuaga acccguggaa      960

aaagcccucc gcgacgccaa acuagacaaa gcacaaaucc acgacuucgu acuaggcggc     1020

gggcuccaca gccacccaca aggcgcagaa gucgccgcag gccuacucca acgacaaggc     1080

gcagaacaag aacaccagcc auaa                                            1104


<210>  5889
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  5889
augcccgaag aagugcacca cggggaagag gaagucgaaa ccuucgccuu ccaggccgag       60

auagcccaac ucaugagcuu aaucauaaac accuucuacu ccaacaaaga aaucuuccuc      120

agagaguuga uaucaaacgc aagcgacgcc cuggacaaga uaagauacga aagccuaaca      180

gacccaucaa aacuggacuc aggaaaggag uuaaaaauag acaucauccc aaacccacaa      240

gaacgcacgc ucacccucgu ggacaccgga auaggaauga caaaagccga ccucauaaac      300

aaucucggca cgauagccaa gagcgggaca aaagccuuca uggaggcccu acaagcagga      360

gccgacauaa gcaugaucgg acaauucggc guaggcuucu acagcgcaua ccucgucgcc      420

gaaaaggugg uaguaaucac aaaacacaac gacgacgaac aauacgccug ggaaagcagc      480

gccggcggga gcuucacagu cagagcagac cacggcgaac cuauaggacg cgggacuaaa      540

guaauccucc accuaaagga agaccaaacc gaauacuuag aagaacgcag ggucaaggaa      600

gucgucaaaa aacacagcca guucaucggc uaccccauaa cccucuaccu ggaaaaagag      660

agggaaaagg aaauaaguga cgacgaggcc gaggaagaaa aaggagaaaa agaagaagaa      720

gacaaagacg acgaagaaaa gcccaagauc gaagacguag gaagcgacga agaagacgac      780

ucaggaaagg acaagaaaaa aaaaacgaaa aaaaucaaag agaaauacau cgaccaagaa      840

gaacugaaca aaacaaaacc aaucuggacc aggaaccccg augacaucac acaagaagaa      900

uacggggaau uuuacaaauc gcuaacaaac gacugggagg accaccucgc gguaaagcac      960

uucagcgugg aaggacaacu cgaauuuaga gcacuacuau ucaucccaag gagagcgcca     1020

uucgaccugu ucgaaaacaa gaaaaaaaaa aacaacauaa agcuauacgu ccgacgaguc     1080

uucauaaugg acucaugcga cgaacugauc ccagaauacc uaaacuucau ccggggcgua     1140

guagacuccg aagaccuccc acucaacauc agccgagaaa ugcuacaaca gagcaagaua     1200

cugaaaguga ucagaaaaaa caucguaaaa aagugccuag aacuauucag cgaauuagca     1260

gaggauaaag aaaacuacaa gaaauucuac gaagccuuca gcaagaaccu aaaacugggc     1320

auacacgaag acagcaccaa ucgaaggcgc cuaagcgaac uacuaagaua ccacacaagu     1380

cagagcggcg acgagaugac gagccuaucc gaauacguua gccggaugaa agaaacgcaa     1440

aagucaauau acuacaucac cggagagagc aaggaacaag uagcgaacuc ggcauucguc     1500

gaacgcgugc gaaagcgcgg auucgaaguc guauacauga cggagcccau cgacgaguac     1560

uguguacaac agcucaaaga auuugacggc aaaagccuag ucucaguaac caaagaagga     1620

cuagaauugc ccgaagacga agaagagaag aaaaaaaugg aagaaucaaa agccaaauuc     1680

gagaacuugu gcaagcugau gaaagagauc cuagacaaaa agguagaaaa ggucacgauc     1740

ucaaaccggc uggugagcuc gcccugcugc aucgucacga gcacauacgg cuggacagca     1800

aacauggaac gaauaaugaa agcacaagcc cucagagaca acucaaccau gggguacaug     1860

auggccaaga aacaccucga aauaaacccc gaccacccua uaguagaaac gcucaggcaa     1920

aaggccgaag cagacaaaaa cgacaaagcc guaaaagacc ucgugguccu gcucuuugaa     1980

acagcccuac ucucaagcgg auuuucacug gaggacccac aaacccacag caacagaauc     2040

uaccgaauga uuaagcucgg acuggguauu gacgaggacg aaguagccgc ggaagaaccc     2100

aacgcggcag uccccgacga aaucccgccc cuggaagggg acgaggacgc aucaagaaug     2160

gaagaggucg acuag                                                      2175


<210>  5890
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  5890
augaacuccu ucuccaccuc cgccuucggc cccgucgccu ucucccucgg ccuccuacuc       60

guacuccccg ccgccuuccc agcccccguc cccccaggcg aagacuccaa agacgucgcc      120

gccccccacc gccaaccucu caccucaucc gaacgcaucg acaaacaaau acgcuacauc      180

cucgacggca ucuccgcccu ccgcaaagaa accugcaaca aaucaaacau gugcgaaucc      240

ucaaaagaag cccucgccga aaacaaccua aaccucccca aaauggccga aaaagacggc      300

ugcuuccaau ccggcuucaa cgaagaaaca ugccucguca aaauaaucac cggacuccuc      360

gaauuugaag ucuaccucga auaccuacaa aaccgcuucg aaucauccga agaacaagcc      420

cgcgccgucc aaaugucaac caaaguccuc auccaauucc uccaaaaaaa agccaaaaac      480

cucgacgcca ucacaacccc cgaccccacc accaacgccu cccuacucac caaacuccaa      540

gcccaaaacc aauggcucca agacaugacc acccaccuca uccuccgcuc cuucaaagaa      600

uuucuccaau ccucccuccg cgcccuccga caaauguag                             639


<210>  5891
<211>  1416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_002418.1__HsMMP13

<400>  5891
augcaccccg gcguacucgc agccuuccua uuccuauccu ggacccacug ccgcgcauua       60

ccccuccccu caggaggcga ugaagacgac cuuuccgaag aagaccugca auucgccgaa      120

cgcuaccucc gauccuacua ccaccccacc aaccucgccg gcauacucaa agaaaacgca      180

gccucaucca ugacagaacg ccuccgcgaa augcaauccu ucuuuggccu cgaagucacc      240

ggaaaacuug acgacaacac gcuagacguc augaaaaaac ccagaugcgg aguccccgac      300

gucggcgaau acaacgucuu ccccagaacc cuaaaauggu caaaaaugaa ccucaccuac      360

agaauaguca acuacacccc ugacaugacc cacuccgaag uagaaaaagc cuucaaaaaa      420

gccuucaaag ucuggucuga cguuaccccc cucaacuuca cccgacucca cgacggcauc      480

gccgacauaa ugaucuccuu cggaaucaaa gaacacggcg acuucuaccc cuucgacgga      540

ccaucaggcc uacucgccca cgccuuccca ccaggaccca acuacggagg cgacgcccac      600

uucgaugacg acgaaaccug gaccuccucc uccaaaggcu acaaccucuu ccuaguagcc      660

gcacacgaau uuggccacuc acuaggacua gaccacucca aagaccccgg cgcucuuaug      720

uuccccaucu acaccuacac ugggaaaucc cacuucaugc uccccgacga cgacguacaa      780

ggcauccaaa gccucuacgg cccgggcgac gaagauccca accccaaaca ccccaaaaca      840

ccagacaaau gcgaccccuc acuaucacua gacgcaauca ccucccuccg uggcgaaacu      900

augaucuuca aagaccgauu cuucuggcgc uuacaccccc aacaagucga cgccgaacuc      960

uuccuuacca aaucauucug gcccgaacuc cccaaccgca ucgacgccgc cuacgaacac     1020

cccagccaug accucaucuu uaucuuccgc gggagaaaau ucugggcacu aaacggauac     1080

gacauacucg aaggcuaccc aaaaaaaauc uccgaacuag gccucccaaa ggaagucaaa     1140

aagaucuccg cagcaguaca cuucgaagac accggcaaaa cccuccuauu cucagguaac     1200

caaguauggc gcuacgacga caccaaccac aucauggaca aagacuaccc ccgccucauc     1260

gaagaagacu uccccggcau aggcgacaaa gucgacgccg ucuaugaaaa aaacggcuac     1320

auauacuucu uuaacggccc cauccaauuu gaauacucca uaugguccaa ccgcaucgua     1380

cgcguuaugc cagccaacuc cauccucugg ugcuaa                               1416


<210>  5892
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  5892
augcaccgcc uaaucuucgu cuacacccua aucugcgcca acuucugcuc cugccgagac       60

accuccgcca ccccacaauc cgccuccaua aaagcacucc ggaaugccaa cuuacgccgg      120

gacgaccuau accgucgaga cgaaacaauc caaguaaaag gaaacggcua cgugcaaucg      180

ccccgauucc caaacuccua cccacgcaac cuccuccuca ccuggcgacu acacucccaa      240

gaaaacacuc gcauccaacu cgucuucgac aaccaguucg gccuggaaga agccgaaaac      300

gacaucugcc gcuacgacuu cgucgaaguc gaagacauau cagaaaccuc caccaucaua      360

cgcggccgcu ggugcggcca caaagaggua cccccccgca ucaaaucccg cacaaaccaa      420

aucaaaauaa ccuucaaauc agacgacuac uucguagcua aacccggauu caaaaucuac      480

uacucccucc uagaagacuu ccaacccgcc gcagcauccg agaccaacug ggaauccgua      540

accuccucca uauccggcgu auccuacaac agccccuccg ucacagaccc cacccuuaua      600

gccgacgccc ucgacaaaaa aaucgccgaa uuugacaccg ucgaagaucu ccuaaaauac      660

uucaaccccg aaucauggca agaagaccuc gaaaacaugu accuagacac cccacgauac      720

cgcggacgcu cauaccacga ccgaaaaucc aaagucgacc ucgaccgacu caacgacgac      780

gccaaacgcu acagcugcac accacgcaac uacuccguca acauccgcga agaacuaaaa      840

cucgccaacg uagucuucuu cccccgcugc cuucucgucc aaagaugcgg cggcaacugc      900

ggcuguggaa ccguaaacug gcgcagcugc accuguaacu caggcaaaac cgucaaaaaa      960

uaccacgaag uccuccaauu cgaaccaggc cacaucaaac gccgcggccg agccaaaaca     1020

auggcccucg ucgacaucca gcucgaccac cacgaacgcu gcgacugcau augcuccagc     1080

cgccccccuc gcuaa                                                      1095


<210>  5893
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  5893
auggucaccc acuccaaauu cccugccgca ggcauguccc gaccccucga caccucccuc       60

cgacucaaaa ccuucuccuc aaaguccgaa uaccaacucg ucgucaacgc cguccguaaa      120

cuccaagaau ccggcuucua cugguccgcc gucaccggug gugaagcaaa ccuccuccuc      180

uccgcagaac ccgccggcac cuuccucauc cgcgacuccu cagaccaacg ccacuucuuc      240

acccucucag ucaaaaccca auccggcacc aaaaaccucc gcauccaaug cgaaggcggc      300

uccuucuccc uccaauccga cccacgcucc acacaaccug ucccacgcuu cgacugcguc      360

cucaaacucg uccaccacua caugccaccc cccggcgccc ccuccuuccc aucccccccc      420

accgaacccu ccucagaagu ccccgaacaa cccucagccc aaccccuccc cggcuccccc      480

ccccgccgcg cauacuacau cuacuccggc ggcgaaaaaa ucccacucgu acucucccgc      540

ccccucuccu ccaacgucgc cacccuacaa caccucugcc gcaaaaccgu caacggccac      600

cucgacuccu acgaaaaagu cacccaacua cccggcccca uccgcgaauu ucucgaccaa      660

uacgaugcac cccuauaa                                                    678


<210>  5894
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_003227.1__HsTGFA

<400>  5894
augguccccu ccgccggcca acucgcccua uucgcccucg gaaucguccu cgcagccugc       60

caagcccucg aaaacuccac cuccccccuc uccgccgacc cccccgucgc cgccgccguc      120

gucucccacu ucaacgacug ccccgacucc cacacccaau ucugcuucca cggcaccugu      180

cgcuuccucg uccaagaaga caaacccgcc ugcgucugcc acuccggcua cgucggcgcc      240

cgcugcgaac acgccgaccu ccucgccguc gucgccgccu cccaaaaaaa acaagccauc      300

accgcccucg ucgucgucuc caucgucgcc cucgccgucc ucaucaucac cuguguccua      360

auccacugcu gccaaguccg caaacacugc gaauggugcc gcgcccucau cugccgccac      420

gaaaaacccu ccgcccuccu caaaggccgc accgccugcu gccacuccga aacagucguu      480

uaa                                                                    483


<210>  5895
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  5895
augcacuacu gcguccucuc cgccuuccuc auauuacacc ucgucaccgu ugcccuaucc       60

cucucgacuu gcuccacccu cgacauggac caauucaugc gcaaaagaau cgaagcaauc      120

cgaggccaaa uccucucaaa acucaaacuu acaucccccc cugaagacua uccagaaccc      180

gaggaagucc ccccugaagu cauauccaua uacaacagca cccgcgaccu acuccaagaa      240

aaagccucgc gacgagccgc agccugcgaa cgcgaacgca gcgacgaaga auacuacgcc      300

aaggaagucu acaaaaucga caugccgccc uucuucccau cagagaaugc uauccccccc      360

accuucuacc gaccauacuu ccgcaucguc cgcuucgacg ucuccgcaau ggaaaaaaac      420

gccuccaacc ucgucaaagc cgaauuucgc gucuuccgcc ugcaaaaccc caaagcccgc      480

guucccgaac aacgcaucga acucuaccaa auacucaaau ccaaagaccu caccucuccc      540

acccaacguu acaucgacuc uaaaguaguc aaaacacgcg ccgaaggcga auggcucucc      600

uucgacguaa ccgacgccgu acacgaaugg cuccaccaca aagacagaaa ccucggauuc      660

aaaaucuccc uacacugccc cugcugcacu uucguccccu ccaacaacua cauaauuccc      720

aacaaauccg aagaacuuga agcccgcuuc gccggcaucg acggaaccuc gaccuacacu      780

ucaggcgacc agaaaaccau uaaauccacc cgcaaaaaaa acucgggcaa aacaccccac      840

cuccuacuca ugcuccuccc auccuaccgg cuagaauccc aacaaaccaa ccgacgcaaa      900

aaacgagccc ucgacgcagc cuacugcuuc cguaacgucc aagacaauug cugccuacgc      960

ccacucuaca ucgauuucaa acgugaccuc ggauggaaau ggauccauga acccaaaggc     1020

uacaacgcca acuucugcgc aggcgcaugc cccuaccucu ggagcuccga cacccaacac     1080

ucccgcgucc uaagccuuua caacaccauc aaccccgaag ccucagccuc ccccugcugc     1140

gucucccaag accucgaacc acuaacaauc cucuacuaca ucggcaaaac ccccaaaaua     1200

gaacaacucu ccaacaugau cgucaaaucc ugcaaaugcu ccuaa                     1245


<210>  5896
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  5896
auggcaccag ucgcagucug ggccgcccuc gccguaggcc uugaacucug ggcagccgcc       60

cacgcccucc cagcacaagu cgcauucacu cccuacgcac ccgaacccgg cuccaccugu      120

cgccuacgcg aauacuauga ccaaacagca caaaugugcu gcuccaaaug cucucccggc      180

caacacgcua aaguauucug cacaaaaacc ucugacaccg uaugcgacuc augcgaagac      240

uccacauaua cccaacucug gaacuggguc cccgaaugcc ucuccugcgg cucccgcugc      300

agcucagacc aaguagaaac ccaagcaugc acccgcgagc aaaaccgcau cugcacaugc      360

cgccccggcu gguacugcgc ucucuccaaa caagaaggcu gcagacuuug ugcaccucug      420

aggaaaugcc gaccaggcuu ugguguagca agacccggua ccgaaaccuc agacgucguc      480

ugcaaaccgu gugcacccgg caccuucuca aacaccaccu ccucuaccga caucugccga      540

ccacaucaaa ucugcaacgu agucgccauc ccaggcaacg ccuccaugga cgccguaugc      600

accucgaccu cccccacccg cuccauggcc cccggcgccg uacaccuacc ccaacccguc      660

uccacccgau cccagcacac ccaacccacc ccagaaccca gcaccgcccc gucaaccuca      720

uuccuacucc caaugggccc cuccccaccc gcagaaggcu ccacaggcga uuucgcccuc      780

cccguaggac uaauaguugg cgucaccgcc cuaggccucc uuaucaucgg cguagucaac      840

ugcgucauca ugacccaagu caaaaaaaaa ccccucugcc uccaacgcga agccaaaguc      900

ccacaccucc cagccgacaa agcccgcgga acccaaggcc ccgaacaaca acaccuccuc      960

aucaccgccc ccucaucaag cuccuccuca cucgaaucau ccgccuccgc ccucgaucga     1020

cgcgccccca cacgcaacca accacaagcc ccaggcguag aagcguccgg cgccggcgaa     1080

gcccgcgccu ccaccggcuc guccgacucc ucaccaggag gucacggcac ccaaguaaau     1140

gucaccugua ucgugaacgu uuguuccucc ucagaucaca gcucccaaug uucuucccaa     1200

gccuccucca caaugggcga caccgauucc agccccucag aaucccccaa agacgaacaa     1260

gucccauucu caaaagaaga gugugccuuc cgaucccagc ucgaaacacc agaaacccua     1320

cucgguucaa ccgaagaaaa accccucccc cucggcgucc cagacgcagg caugaaaccc     1380

uccuaa                                                                1386


<210>  5897
<211>  699
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_001165094.1__HsVEGFA

<400>  5897
augaacuucc uccuaagcug gguccacugg ucccucgccc uacuccucua ccuacaccac       60

gccaaauggu cccaagccgc acccauggcc gaaggcggcg gccaaaacca ccacgaaguc      120

gucaaauuca uggacgucua ccaacgcuca uacugccacc ccaucgaaac ccucgucgac      180

aucuuccaag aauaccccga cgaaauagaa uacaucuuca aacccucaug cgucccccuc      240

augcgcugcg gcggcugcug caacgacgaa ggacucgaau gcguacccac cgaagaauca      300

aacaucacaa ugcaaaucau gcgcaucaaa ccccaccaag gccaacacau cggcgaaaug      360

uccuuccucc aacacaacaa augcgaaugc cgccccaaaa aagaccgagc acgacaagaa      420

aaaaaauccg uccgaggcaa aggcaaaggc caaaaacgaa aaagaaaaaa aucccgcuac      480

aaauccuggu ccguauacgu cggcgcccga ugcugccuca ugccaugguc ccuccccggc      540

ccccacccau gcggccccug cuccgaacgc cgcaaacacc ucuucgucca agacccccaa      600

accugcaaau gcuccugcaa aaacaccgac uccagaugca aagcccgcca acucgaacuc      660

aacgaacgca ccugucgcug cgacaaaccc cgacgcuaa                             699


<210>  5898
<211>  624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (opt11) from Homo 
       sapiens__NP_003368.1__HsVEGFB

<400>  5898
augucccccc uccuccgccg ccuccuccuc gcagcccuac uccaacuagc ccccgcacaa       60

gcccccgucu cccaacccga cgcccccggc caccaacgca aaguagucuc cuggauagac      120

gucuacaccc gcgccaccug ucaaccccgc gaagucguag ucccccucac agucgaacuc      180

augggcacag ucgccaaaca acucguaccc ucaugcguca ccguccaaag augcggcggc      240

ugcugccccg acgacggccu cgaaugcguc cccaccggcc aacaccaagu ccgcaugcaa      300

auacucauga uccgauaccc aucaucccaa cuaggagaaa ugucacucga agaacacucu      360

caaugcgaau gcagacccaa aaaaaaagac ucagccguaa aaccagaccg cgccgcaaca      420

ccccaccacc gcccccaacc acgaucaguc cccggcuggg acuccgcccc cggcgccccc      480

ucccccgccg acaucaccca ccccaccccc gcccccggcc cauccgccca cgccgccccc      540

uccaccaccu cugcccuaac ccccggcccc gccgccgccg ccgcagacgc cgccgccuca      600

uccgucgcca aaggcggcgc cuaa                                             624


<210>  5899
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt11)

<400>  5899
gggagaaagc uuaccauggu cgccggcacc cguugccucc uugcccuccu ccuaccccaa       60

guccuacuag gcggagcagc cggccucguc cccgaacucg gccgccgcaa auucgccgcc      120

gccucauccg gacgccccuc cucacaaccc agcgacgaag uacucucaga auuugaacuu      180

cgucuacucu ccauguucgg ccucaaacaa cgacccacuc ccucccgcga cgcagucguc      240

cccccuuaca ugcuagaccu uuaccgccgc cacuccggcc aacccggauc acccgccccc      300

gaccaucgcc ucgaaagagc cgccucccga gccaauaccg uccgcucauu ccaccacgaa      360

gaaucacucg aagaacuacc cgaaaccagc ggaaaaacaa cacgcagauu cuucuucaac      420

cucuccagca uccccaccga agaauuuauc accuccgccg aacuacaagu auucagagaa      480

caaaugcagg acgcccucgg caacaacucc agcuuccacc accgcaucaa cauauacgaa      540

auaaucaaac ccgccacagc uaacuccaag uuccccguca cacgccuacu cgacacccgc      600

cuagucaacc aaaaugccuc ccgcugggaa uccuucgacg ucacccccgc cgucaugcga      660

uggaccgcac aaggccacgc caaucacggc uucgucguag aaguugcaca ccuagaagaa      720

aaacaaggcg ucuccaaacg ccacguccgc aucuccagau cccuacacca agacgaacac      780

ucaugguccc aaauccgccc ccuccuaguc accuucggac augacggcaa aggacacccg      840

cuccacaaac gcgaaaaacg ccaagccaaa cacaaacaac gcaaacgccu caaaucaucc      900

ugcaaacgcc acccacucua cguagacuuc uccgacguag gauggaacga cuggauaguc      960

gcacccccag gcuaccacgc auucuacugc cacggagaau gcccauuccc acuugccgac     1020

caccucaacu ccaccaacca cgcuaucgua caaacacucg ucaacuccgu caacucaaaa     1080

aucccaaaag caugcugcgu ccccacagaa cucucagcca ucuccaugcu cuaccucgac     1140

gaaaacgaaa aggucguccu aaaaaacuac caagacaugg ucgucgaagg cugcggcugc     1200

cgcuagggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  5900
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt11)

<400>  5900
gggagaaagc uuaccaugca cguccgauca cuacgcgccg cagccccaca cuccuucgua       60

gcacucuggg caccccuauu cuuacuccgc uccgcacuag ccgacuucuc ccucgacaac      120

gaaguccacu cgagcuucau ccaccgccgc cuacgguccc aagaaagacg cgaaaugcaa      180

cgcgaaaucc ucucaauucu aggacucccc caccgccccc gcccccaccu ccaaggcaaa      240

cacaacucug cccccauguu caugcucgac cucuacaacg ccauggcagu agaagaagga      300

ggcggacccg gcggccaagg cuucucauac cccuacaaag ccguuuucuc aacccaaggc      360

ccgccccucg caucccucca agacucacac uuccuaaccg acgccgacau gguaauguca      420

uucgucaacc ucguagaaca ugacaaagaa uuuuuccacc cccgcuauca ccaccgcgaa      480

uuucgauucg accucucgaa aauacccgaa ggcgaagccg ugaccgcagc cgaauuucgc      540

auauacaaag acuacauccg cgaacgcuuc gacaacgaaa cauuccgcau cuccgucuac      600

caagugcucc aagaacaccu cggccgcgaa agcgaccucu uccuacuuga cucccgcaca      660

cuuugggccu cugaagaagg uuggcucgua uucgacauaa cagccaccuc aaaccacugg      720

guagucaacc cccgucacaa ccuaggacuc cagcuaucag uagaaacacu cgacggccag      780

agcaucaacc ccaaacuugc gggacucauc ggccgccacg gaccacaaaa caagcagccc      840

uucauggucg ccuucuuuaa agccaccgaa guacauuuca gauccauacg cuccaccggg      900

uccaaacaac gaucacaaaa ccgauccaaa accccaaaaa accaagaagc ucuacgaaug      960

gcaaacguag cugaaaacag cuccucagac caacgccaag ccugcaaaaa acacgaacuc     1020

uacgucuccu uccgagaccu cggcuggcaa gacuggauca ucgccccaga aggcuacgca     1080

gcauacuacu gcgaaggcga augcgccuuc ccccuuaacu cuuacaugaa cgccaccaac     1140

cacgcaaucg uccagacccu cguacacuuc aucaaccccg aaacuguccc caaacccugc     1200

ugcgccccca cccaauuaaa cgcaaucucc guccucuacu ucgacgacuc cucgaacguc     1260

auacucaaaa aauaccgaaa cauggucguc cgcgccugcg gcugccauua aggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  5901
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt11)

<400>  5901
gggagaaagc uuaccaugaa agccuccgcc gcccuccucu gccuccuccu caccgccgcc       60

gccuucuccc cccaaggccu agcccaaccc gucggcauca acaccuccac caccuguugc      120

uaccgauuca ucaacaaaaa aauccccaaa caacgccucg aauccuaccg ccgcaccacc      180

uccucacacu gcccccgcga agccgucauc uucaaaacca aacucgacaa agaaaucugc      240

gccgacccca cccaaaaaug gguccaagac uucaugaaac accucgacaa aaaaacccaa      300

acccccaaac ucuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  5902
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt11)

<400>  5902
gggagaaagc uuaccaugca caaauggauc cucaccugga uccuccccac ccuccucuac       60

cgcuccugcu uccacaucau cugccucguc ggcaccaucu cccucgccug caacgacaug      120

acccccgaac aaauggccac aaacgucaac ugcuccuccc ccgaacgcca cacccgcucc      180

uacgacuaca uggaaggcgg cgacauccgc guccgccgac ucuucugccg cacccaaugg      240

uaccuacgca ucgacaaacg cggcaaagua aaaggcaccc aagaaaugaa aaacaacuac      300

aacaucaugg aaauccgcac agucgccguc ggcauagucg caaucaaagg cgucgaaucc      360

gaauuuuacc ucgccaugaa caaagaaggc aaacucuacg ccaaaaaaga augcaacgaa      420

gacugcaacu ucaaagaacu cauccucgaa aaccacuaca acaccuacgc cuccgccaaa      480

uggacccaca acggcggcga aauguucguc gcccucaacc aaaaaggcau ccccguccgc      540

ggcaaaaaaa ccaaaaaaga acaaaaaacc gcccacuucc uccccauggc caucaccuaa      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  5903
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt11)

<400>  5903
gggagaaagc uuaccaugca agccccccgc gaacuagccg uaggcaucga ccucggcaca       60

accuacagcu gugucggcgu auuccaacaa ggcagaguag aaauccuagc caacgaccaa      120

ggcaacagaa cgaccccauc auacgucgcg uucaccgaca cagaaaggcu aguaggagac      180

gcagcaaaau cccaagcagc ccuaaacccg cacaacacug uauucgacgc caaacgccua      240

aucggacgaa aauucgcaga cacaaccguc caaucagaca ugaaacacug gccauuccaa      300

gucgucuccg aagguggaaa acccaaagua cgaguaugcu accgagggga agacaaaaca      360

uucuacccag aagaaauaag cucaauggua cuaagcaaaa ugaaagaaac cgcggaagcc      420

uaccuaggcc aaccaguaaa acacgccgua aucacggucc cgaccuacuu cagcaacucc      480

cagagacagg ccaccaaaga cgcaggagca aucgcaggcc uaaaaguacu cccaaucaua      540

aacgaagcca cagccgcagc aauagccuac ggccuggacc gaagaggagc cggcaaacga      600

aacguacuca uauucgaccu aggaggagga acauucgacg uauccguacu cucgaucgac      660

gccggggucu ucgaaguaaa agcuaccgcc ggcgacaccc accuaggagg cgaagacuuc      720

gacaaccgcc uagucaacca cuucauggaa gaauuucgca gaaaacacgg caaagaccua      780

agcggaaaca aacgagcccu cagacgacuc cgaacagccu gcgaacgagc caaacgcacc      840

ccaucaagca gcacccaggc cacacuagaa aucgacuccc uauucgaagg cguagacuuc      900

uacaaaagca ucaccagagc cagauucgaa gaacucugca gcgaccuauu ccgaagcacc      960

cuagaacccg uggaaaaagc ccuccgcgac gccaaacuag acaaagcaca aauccacgac     1020

uucguacuag gcggcgggcu ccacagccac ccacaaggcg cagaagucgc cgcaggccua     1080

cuccaacgac aaggcgcaga acaagaacac cagccauaag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  5904
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt11)

<400>  5904
gggagaaagc uuaccaugcc cgaagaagug caccacgggg aagaggaagu cgaaaccuuc       60

gccuuccagg ccgagauagc ccaacucaug agcuuaauca uaaacaccuu cuacuccaac      120

aaagaaaucu uccucagaga guugauauca aacgcaagcg acgcccugga caagauaaga      180

uacgaaagcc uaacagaccc aucaaaacug gacucaggaa aggaguuaaa aauagacauc      240

aucccaaacc cacaagaacg cacgcucacc cucguggaca ccggaauagg aaugacaaaa      300

gccgaccuca uaaacaaucu cggcacgaua gccaagagcg ggacaaaagc cuucauggag      360

gcccuacaag caggagccga cauaagcaug aucggacaau ucggcguagg cuucuacagc      420

gcauaccucg ucgccgaaaa ggugguagua aucacaaaac acaacgacga cgaacaauac      480

gccugggaaa gcagcgccgg cgggagcuuc acagucagag cagaccacgg cgaaccuaua      540

ggacgcggga cuaaaguaau ccuccaccua aaggaagacc aaaccgaaua cuuagaagaa      600

cgcaggguca aggaagucgu caaaaaacac agccaguuca ucggcuaccc cauaacccuc      660

uaccuggaaa aagagaggga aaaggaaaua agugacgacg aggccgagga agaaaaagga      720

gaaaaagaag aagaagacaa agacgacgaa gaaaagccca agaucgaaga cguaggaagc      780

gacgaagaag acgacucagg aaaggacaag aaaaaaaaaa cgaaaaaaau caaagagaaa      840

uacaucgacc aagaagaacu gaacaaaaca aaaccaaucu ggaccaggaa ccccgaugac      900

aucacacaag aagaauacgg ggaauuuuac aaaucgcuaa caaacgacug ggaggaccac      960

cucgcgguaa agcacuucag cguggaagga caacucgaau uuagagcacu acuauucauc     1020

ccaaggagag cgccauucga ccuguucgaa aacaagaaaa aaaaaaacaa cauaaagcua     1080

uacguccgac gagucuucau aauggacuca ugcgacgaac ugaucccaga auaccuaaac     1140

uucauccggg gcguaguaga cuccgaagac cucccacuca acaucagccg agaaaugcua     1200

caacagagca agauacugaa agugaucaga aaaaacaucg uaaaaaagug ccuagaacua     1260

uucagcgaau uagcagagga uaaagaaaac uacaagaaau ucuacgaagc cuucagcaag     1320

aaccuaaaac ugggcauaca cgaagacagc accaaucgaa ggcgccuaag cgaacuacua     1380

agauaccaca caagucagag cggcgacgag augacgagcc uauccgaaua cguuagccgg     1440

augaaagaaa cgcaaaaguc aauauacuac aucaccggag agagcaagga acaaguagcg     1500

aacucggcau ucgucgaacg cgugcgaaag cgcggauucg aagucguaua caugacggag     1560

cccaucgacg aguacugugu acaacagcuc aaagaauuug acggcaaaag ccuagucuca     1620

guaaccaaag aaggacuaga auugcccgaa gacgaagaag agaagaaaaa aauggaagaa     1680

ucaaaagcca aauucgagaa cuugugcaag cugaugaaag agauccuaga caaaaaggua     1740

gaaaagguca cgaucucaaa ccggcuggug agcucgcccu gcugcaucgu cacgagcaca     1800

uacggcugga cagcaaacau ggaacgaaua augaaagcac aagcccucag agacaacuca     1860

accauggggu acaugauggc caagaaacac cucgaaauaa accccgacca cccuauagua     1920

gaaacgcuca ggcaaaaggc cgaagcagac aaaaacgaca aagccguaaa agaccucgug     1980

guccugcucu uugaaacagc ccuacucuca agcggauuuu cacuggagga cccacaaacc     2040

cacagcaaca gaaucuaccg aaugauuaag cucggacugg guauugacga ggacgaagua     2100

gccgcggaag aacccaacgc ggcagucccc gacgaaaucc cgccccugga aggggacgag     2160

gacgcaucaa gaauggaaga ggucgacuag ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  5905
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt11)

<400>  5905
gggagaaagc uuaccaugaa cuccuucucc accuccgccu ucggccccgu cgccuucucc       60

cucggccucc uacucguacu ccccgccgcc uucccagccc ccgucccccc aggcgaagac      120

uccaaagacg ucgccgcccc ccaccgccaa ccucucaccu cauccgaacg caucgacaaa      180

caaauacgcu acauccucga cggcaucucc gcccuccgca aagaaaccug caacaaauca      240

aacaugugcg aauccucaaa agaagcccuc gccgaaaaca accuaaaccu ccccaaaaug      300

gccgaaaaag acggcugcuu ccaauccggc uucaacgaag aaacaugccu cgucaaaaua      360

aucaccggac uccucgaauu ugaagucuac cucgaauacc uacaaaaccg cuucgaauca      420

uccgaagaac aagcccgcgc cguccaaaug ucaaccaaag uccucaucca auuccuccaa      480

aaaaaagcca aaaaccucga cgccaucaca acccccgacc ccaccaccaa cgccucccua      540

cucaccaaac uccaagccca aaaccaaugg cuccaagaca ugaccaccca ccucauccuc      600

cgcuccuuca aagaauuucu ccaauccucc cuccgcgccc uccgacaaau guagggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  5906
<211>  1633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt11)

<400>  5906
gggagaaagc uuaccaugca ccccggcgua cucgcagccu uccuauuccu auccuggacc       60

cacugccgcg cauuaccccu ccccucagga ggcgaugaag acgaccuuuc cgaagaagac      120

cugcaauucg ccgaacgcua ccuccgaucc uacuaccacc ccaccaaccu cgccggcaua      180

cucaaagaaa acgcagccuc auccaugaca gaacgccucc gcgaaaugca auccuucuuu      240

ggccucgaag ucaccggaaa acuugacgac aacacgcuag acgucaugaa aaaacccaga      300

ugcggagucc ccgacgucgg cgaauacaac gucuucccca gaacccuaaa auggucaaaa      360

augaaccuca ccuacagaau agucaacuac accccugaca ugacccacuc cgaaguagaa      420

aaagccuuca aaaaagccuu caaagucugg ucugacguua ccccccucaa cuucacccga      480

cuccacgacg gcaucgccga cauaaugauc uccuucggaa ucaaagaaca cggcgacuuc      540

uaccccuucg acggaccauc aggccuacuc gcccacgccu ucccaccagg acccaacuac      600

ggaggcgacg cccacuucga ugacgacgaa accuggaccu ccuccuccaa aggcuacaac      660

cucuuccuag uagccgcaca cgaauuuggc cacucacuag gacuagacca cuccaaagac      720

cccggcgcuc uuauguuccc caucuacacc uacacuggga aaucccacuu caugcucccc      780

gacgacgacg uacaaggcau ccaaagccuc uacggcccgg gcgacgaaga ucccaacccc      840

aaacacccca aaacaccaga caaaugcgac cccucacuau cacuagacgc aaucaccucc      900

cuccguggcg aaacuaugau cuucaaagac cgauucuucu ggcgcuuaca cccccaacaa      960

gucgacgccg aacucuuccu uaccaaauca uucuggcccg aacuccccaa ccgcaucgac     1020

gccgccuacg aacaccccag ccaugaccuc aucuuuaucu uccgcgggag aaaauucugg     1080

gcacuaaacg gauacgacau acucgaaggc uacccaaaaa aaaucuccga acuaggccuc     1140

ccaaaggaag ucaaaaagau cuccgcagca guacacuucg aagacaccgg caaaacccuc     1200

cuauucucag guaaccaagu auggcgcuac gacgacacca accacaucau ggacaaagac     1260

uacccccgcc ucaucgaaga agacuucccc ggcauaggcg acaaagucga cgccgucuau     1320

gaaaaaaacg gcuacauaua cuucuuuaac ggccccaucc aauuugaaua cuccauaugg     1380

uccaaccgca ucguacgcgu uaugccagcc aacuccaucc ucuggugcua aggacuaguu     1440

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1500

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1620

agccaccaga auu                                                        1633


<210>  5907
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt11)

<400>  5907
gggagaaagc uuaccaugca ccgccuaauc uucgucuaca cccuaaucug cgccaacuuc       60

ugcuccugcc gagacaccuc cgccacccca caauccgccu ccauaaaagc acuccggaau      120

gccaacuuac gccgggacga ccuauaccgu cgagacgaaa caauccaagu aaaaggaaac      180

ggcuacgugc aaucgccccg auucccaaac uccuacccac gcaaccuccu ccucaccugg      240

cgacuacacu cccaagaaaa cacucgcauc caacucgucu ucgacaacca guucggccug      300

gaagaagccg aaaacgacau cugccgcuac gacuucgucg aagucgaaga cauaucagaa      360

accuccacca ucauacgcgg ccgcuggugc ggccacaaag agguaccccc ccgcaucaaa      420

ucccgcacaa accaaaucaa aauaaccuuc aaaucagacg acuacuucgu agcuaaaccc      480

ggauucaaaa ucuacuacuc ccuccuagaa gacuuccaac ccgccgcagc auccgagacc      540

aacugggaau ccguaaccuc cuccauaucc ggcguauccu acaacagccc cuccgucaca      600

gaccccaccc uuauagccga cgcccucgac aaaaaaaucg ccgaauuuga caccgucgaa      660

gaucuccuaa aauacuucaa ccccgaauca uggcaagaag accucgaaaa cauguaccua      720

gacaccccac gauaccgcgg acgcucauac cacgaccgaa aauccaaagu cgaccucgac      780

cgacucaacg acgacgccaa acgcuacagc ugcacaccac gcaacuacuc cgucaacauc      840

cgcgaagaac uaaaacucgc caacguaguc uucuuccccc gcugccuucu cguccaaaga      900

ugcggcggca acugcggcug uggaaccgua aacuggcgca gcugcaccug uaacucaggc      960

aaaaccguca aaaaauacca cgaaguccuc caauucgaac caggccacau caaacgccgc     1020

ggccgagcca aaacaauggc ccucgucgac auccagcucg accaccacga acgcugcgac     1080

ugcauaugcu ccagccgccc cccucgcuaa ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  5908
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt11)

<400>  5908
gggagaaagc uuaccauggu cacccacucc aaauucccug ccgcaggcau gucccgaccc       60

cucgacaccu cccuccgacu caaaaccuuc uccucaaagu ccgaauacca acucgucguc      120

aacgccgucc guaaacucca agaauccggc uucuacuggu ccgccgucac cgguggugaa      180

gcaaaccucc uccucuccgc agaacccgcc ggcaccuucc ucauccgcga cuccucagac      240

caacgccacu ucuucacccu cucagucaaa acccaauccg gcaccaaaaa ccuccgcauc      300

caaugcgaag gcggcuccuu cucccuccaa uccgacccac gcuccacaca accuguccca      360

cgcuucgacu gcguccucaa acucguccac cacuacaugc caccccccgg cgcccccucc      420

uucccauccc cccccaccga acccuccuca gaaguccccg aacaacccuc agcccaaccc      480

cuccccggcu cccccccccg ccgcgcauac uacaucuacu ccggcggcga aaaaauccca      540

cucguacucu cccgcccccu cuccuccaac gucgccaccc uacaacaccu cugccgcaaa      600

accgucaacg gccaccucga cuccuacgaa aaagucaccc aacuacccgg ccccauccgc      660

gaauuucucg accaauacga ugcaccccua uaaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  5909
<211>  700
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt11)

<400>  5909
gggagaaagc uuaccauggu ccccuccgcc ggccaacucg cccuauucgc ccucggaauc       60

guccucgcag ccugccaagc ccucgaaaac uccaccuccc cccucuccgc cgaccccccc      120

gucgccgccg ccgucgucuc ccacuucaac gacugccccg acucccacac ccaauucugc      180

uuccacggca ccugucgcuu ccucguccaa gaagacaaac ccgccugcgu cugccacucc      240

ggcuacgucg gcgcccgcug cgaacacgcc gaccuccucg ccgucgucgc cgccucccaa      300

aaaaaacaag ccaucaccgc ccucgucguc gucuccaucg ucgcccucgc cguccucauc      360

aucaccugug uccuaaucca cugcugccaa guccgcaaac acugcgaaug gugccgcgcc      420

cucaucugcc gccacgaaaa acccuccgcc cuccucaaag gccgcaccgc cugcugccac      480

uccgaaacag ucguuuaagg acuaguuaua agacugacua gcccgauggg ccucccaacg      540

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      660

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            700


<210>  5910
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt11)

<400>  5910
gggagaaagc uuaccaugca cuacugcguc cucuccgccu uccucauauu acaccucguc       60

accguugccc uaucccucuc gacuugcucc acccucgaca uggaccaauu caugcgcaaa      120

agaaucgaag caauccgagg ccaaauccuc ucaaaacuca aacuuacauc ccccccugaa      180

gacuauccag aacccgagga aguccccccu gaagucauau ccauauacaa cagcacccgc      240

gaccuacucc aagaaaaagc cucgcgacga gccgcagccu gcgaacgcga acgcagcgac      300

gaagaauacu acgccaagga agucuacaaa aucgacaugc cgcccuucuu cccaucagag      360

aaugcuaucc cccccaccuu cuaccgacca uacuuccgca ucguccgcuu cgacgucucc      420

gcaauggaaa aaaacgccuc caaccucguc aaagccgaau uucgcgucuu ccgccugcaa      480

aaccccaaag cccgcguucc cgaacaacgc aucgaacucu accaaauacu caaauccaaa      540

gaccucaccu cucccaccca acguuacauc gacucuaaag uagucaaaac acgcgccgaa      600

ggcgaauggc ucuccuucga cguaaccgac gccguacacg aauggcucca ccacaaagac      660

agaaaccucg gauucaaaau cucccuacac ugccccugcu gcacuuucgu ccccuccaac      720

aacuacauaa uucccaacaa auccgaagaa cuugaagccc gcuucgccgg caucgacgga      780

accucgaccu acacuucagg cgaccagaaa accauuaaau ccacccgcaa aaaaaacucg      840

ggcaaaacac cccaccuccu acucaugcuc cucccauccu accggcuaga aucccaacaa      900

accaaccgac gcaaaaaacg agcccucgac gcagccuacu gcuuccguaa cguccaagac      960

aauugcugcc uacgcccacu cuacaucgau uucaaacgug accucggaug gaaauggauc     1020

caugaaccca aaggcuacaa cgccaacuuc ugcgcaggcg caugccccua ccucuggagc     1080

uccgacaccc aacacucccg cguccuaagc cuuuacaaca ccaucaaccc cgaagccuca     1140

gccucccccu gcugcgucuc ccaagaccuc gaaccacuaa caauccucua cuacaucggc     1200

aaaaccccca aaauagaaca acucuccaac augaucguca aauccugcaa augcuccuaa     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  5911
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt11)

<400>  5911
gggagaaagc uuaccauggc accagucgca gucugggccg cccucgccgu aggccuugaa       60

cucugggcag ccgcccacgc ccucccagca caagucgcau ucacucccua cgcacccgaa      120

cccggcucca ccugucgccu acgcgaauac uaugaccaaa cagcacaaau gugcugcucc      180

aaaugcucuc ccggccaaca cgcuaaagua uucugcacaa aaaccucuga caccguaugc      240

gacucaugcg aagacuccac auauacccaa cucuggaacu ggguccccga augccucucc      300

ugcggcuccc gcugcagcuc agaccaagua gaaacccaag caugcacccg cgagcaaaac      360

cgcaucugca caugccgccc cggcugguac ugcgcucucu ccaaacaaga aggcugcaga      420

cuuugugcac cucugaggaa augccgacca ggcuuuggug uagcaagacc cgguaccgaa      480

accucagacg ucgucugcaa accgugugca cccggcaccu ucucaaacac caccuccucu      540

accgacaucu gccgaccaca ucaaaucugc aacguagucg ccaucccagg caacgccucc      600

auggacgccg uaugcaccuc gaccuccccc acccgcucca uggcccccgg cgccguacac      660

cuaccccaac ccgucuccac ccgaucccag cacacccaac ccaccccaga acccagcacc      720

gccccgucaa ccucauuccu acucccaaug ggccccuccc cacccgcaga aggcuccaca      780

ggcgauuucg cccuccccgu aggacuaaua guuggcguca ccgcccuagg ccuccuuauc      840

aucggcguag ucaacugcgu caucaugacc caagucaaaa aaaaaccccu cugccuccaa      900

cgcgaagcca aagucccaca ccucccagcc gacaaagccc gcggaaccca aggccccgaa      960

caacaacacc uccucaucac cgcccccuca ucaagcuccu ccucacucga aucauccgcc     1020

uccgcccucg aucgacgcgc ccccacacgc aaccaaccac aagccccagg cguagaagcg     1080

uccggcgccg gcgaagcccg cgccuccacc ggcucguccg acuccucacc aggaggucac     1140

ggcacccaag uaaaugucac cuguaucgug aacguuuguu ccuccucaga ucacagcucc     1200

caauguucuu cccaagccuc cuccacaaug ggcgacaccg auuccagccc cucagaaucc     1260

cccaaagacg aacaaguccc auucucaaaa gaagagugug ccuuccgauc ccagcucgaa     1320

acaccagaaa cccuacucgg uucaaccgaa gaaaaacccc ucccccucgg cgucccagac     1380

gcaggcauga aacccuccua aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  5912
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt11)

<400>  5912
gggagaaagc uuaccaugaa cuuccuccua agcugggucc acuggucccu cgcccuacuc       60

cucuaccuac accacgccaa auggucccaa gccgcaccca uggccgaagg cggcggccaa      120

aaccaccacg aagucgucaa auucauggac gucuaccaac gcucauacug ccaccccauc      180

gaaacccucg ucgacaucuu ccaagaauac cccgacgaaa uagaauacau cuucaaaccc      240

ucaugcgucc cccucaugcg cugcggcggc ugcugcaacg acgaaggacu cgaaugcgua      300

cccaccgaag aaucaaacau cacaaugcaa aucaugcgca ucaaacccca ccaaggccaa      360

cacaucggcg aaauguccuu ccuccaacac aacaaaugcg aaugccgccc caaaaaagac      420

cgagcacgac aagaaaaaaa auccguccga ggcaaaggca aaggccaaaa acgaaaaaga      480

aaaaaauccc gcuacaaauc cugguccgua uacgucggcg cccgaugcug ccucaugcca      540

uggucccucc ccggccccca cccaugcggc cccugcuccg aacgccgcaa acaccucuuc      600

guccaagacc cccaaaccug caaaugcucc ugcaaaaaca ccgacuccag augcaaagcc      660

cgccaacucg aacucaacga acgcaccugu cgcugcgaca aaccccgacg cuaaggacua      720

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      780

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  5913
<211>  841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt11)

<400>  5913
gggagaaagc uuaccauguc cccccuccuc cgccgccucc uccucgcagc ccuacuccaa       60

cuagcccccg cacaagcccc cgucucccaa cccgacgccc ccggccacca acgcaaagua      120

gucuccugga uagacgucua cacccgcgcc accugucaac cccgcgaagu cguagucccc      180

cucacagucg aacucauggg cacagucgcc aaacaacucg uacccucaug cgucaccguc      240

caaagaugcg gcggcugcug ccccgacgac ggccucgaau gcguccccac cggccaacac      300

caaguccgca ugcaaauacu caugauccga uacccaucau cccaacuagg agaaauguca      360

cucgaagaac acucucaaug cgaaugcaga cccaaaaaaa aagacucagc cguaaaacca      420

gaccgcgccg caacacccca ccaccgcccc caaccacgau caguccccgg cugggacucc      480

gcccccggcg cccccucccc cgccgacauc acccacccca cccccgcccc cggcccaucc      540

gcccacgccg cccccuccac caccucugcc cuaacccccg gccccgccgc cgccgccgca      600

gacgccgccg ccucauccgu cgccaaaggc ggcgccuaag gacuaguuau aagacugacu      660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      840

u                                                                      841


<210>  5914
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt11)

<400>  5914
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucg       60

ccggcacccg uugccuccuu gcccuccucc uaccccaagu ccuacuaggc ggagcagccg      120

gccucguccc cgaacucggc cgccgcaaau ucgccgccgc cucauccgga cgccccuccu      180

cacaacccag cgacgaagua cucucagaau uugaacuucg ucuacucucc auguucggcc      240

ucaaacaacg acccacuccc ucccgcgacg cagucguccc cccuuacaug cuagaccuuu      300

accgccgcca cuccggccaa cccggaucac ccgcccccga ccaucgccuc gaaagagccg      360

ccucccgagc caauaccguc cgcucauucc accacgaaga aucacucgaa gaacuacccg      420

aaaccagcgg aaaaacaaca cgcagauucu ucuucaaccu cuccagcauc cccaccgaag      480

aauuuaucac cuccgccgaa cuacaaguau ucagagaaca aaugcaggac gcccucggca      540

acaacuccag cuuccaccac cgcaucaaca uauacgaaau aaucaaaccc gccacagcua      600

acuccaaguu ccccgucaca cgccuacucg acacccgccu agucaaccaa aaugccuccc      660

gcugggaauc cuucgacguc acccccgccg ucaugcgaug gaccgcacaa ggccacgcca      720

aucacggcuu cgucguagaa guugcacacc uagaagaaaa acaaggcguc uccaaacgcc      780

acguccgcau cuccagaucc cuacaccaag acgaacacuc auggucccaa auccgccccc      840

uccuagucac cuucggacau gacggcaaag gacacccgcu ccacaaacgc gaaaaacgcc      900

aagccaaaca caaacaacgc aaacgccuca aaucauccug caaacgccac ccacucuacg      960

uagacuucuc cgacguagga uggaacgacu ggauagucgc acccccaggc uaccacgcau     1020

ucuacugcca cggagaaugc ccauucccac uugccgacca ccucaacucc accaaccacg     1080

cuaucguaca aacacucguc aacuccguca acucaaaaau cccaaaagca ugcugcgucc     1140

ccacagaacu cucagccauc uccaugcucu accucgacga aaacgaaaag gucguccuaa     1200

aaaacuacca agacaugguc gucgaaggcu gcggcugccg cuagggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  5915
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt11)

<400>  5915
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

uccgaucacu acgcgccgca gccccacacu ccuucguagc acucugggca ccccuauucu      120

uacuccgcuc cgcacuagcc gacuucuccc ucgacaacga aguccacucg agcuucaucc      180

accgccgccu acggucccaa gaaagacgcg aaaugcaacg cgaaauccuc ucaauucuag      240

gacuccccca ccgcccccgc ccccaccucc aaggcaaaca caacucugcc cccauguuca      300

ugcucgaccu cuacaacgcc auggcaguag aagaaggagg cggacccggc ggccaaggcu      360

ucucauaccc cuacaaagcc guuuucucaa cccaaggccc gccccucgca ucccuccaag      420

acucacacuu ccuaaccgac gccgacaugg uaaugucauu cgucaaccuc guagaacaug      480

acaaagaauu uuuccacccc cgcuaucacc accgcgaauu ucgauucgac cucucgaaaa      540

uacccgaagg cgaagccgug accgcagccg aauuucgcau auacaaagac uacauccgcg      600

aacgcuucga caacgaaaca uuccgcaucu ccgucuacca agugcuccaa gaacaccucg      660

gccgcgaaag cgaccucuuc cuacuugacu cccgcacacu uugggccucu gaagaagguu      720

ggcucguauu cgacauaaca gccaccucaa accacugggu agucaacccc cgucacaacc      780

uaggacucca gcuaucagua gaaacacucg acggccagag caucaacccc aaacuugcgg      840

gacucaucgg ccgccacgga ccacaaaaca agcagcccuu cauggucgcc uucuuuaaag      900

ccaccgaagu acauuucaga uccauacgcu ccaccggguc caaacaacga ucacaaaacc      960

gauccaaaac cccaaaaaac caagaagcuc uacgaauggc aaacguagcu gaaaacagcu     1020

ccucagacca acgccaagcc ugcaaaaaac acgaacucua cgucuccuuc cgagaccucg     1080

gcuggcaaga cuggaucauc gccccagaag gcuacgcagc auacuacugc gaaggcgaau     1140

gcgccuuccc ccuuaacucu uacaugaacg ccaccaacca cgcaaucguc cagacccucg     1200

uacacuucau caaccccgaa acugucccca aacccugcug cgcccccacc caauuaaacg     1260

caaucuccgu ccucuacuuc gacgacuccu cgaacgucau acucaaaaaa uaccgaaaca     1320

uggucguccg cgccugcggc ugccauuaag gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  5916
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt11)

<400>  5916
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaag       60

ccuccgccgc ccuccucugc cuccuccuca ccgccgccgc cuucuccccc caaggccuag      120

cccaacccgu cggcaucaac accuccacca ccuguugcua ccgauucauc aacaaaaaaa      180

uccccaaaca acgccucgaa uccuaccgcc gcaccaccuc cucacacugc ccccgcgaag      240

ccgucaucuu caaaaccaaa cucgacaaag aaaucugcgc cgaccccacc caaaaauggg      300

uccaagacuu caugaaacac cucgacaaaa aaacccaaac ccccaaacuc uaaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  5917
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt11)

<400>  5917
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aauggauccu caccuggauc cuccccaccc uccucuaccg cuccugcuuc cacaucaucu      120

gccucgucgg caccaucucc cucgccugca acgacaugac ccccgaacaa auggccacaa      180

acgucaacug cuccuccccc gaacgccaca cccgcuccua cgacuacaug gaaggcggcg      240

acauccgcgu ccgccgacuc uucugccgca cccaauggua ccuacgcauc gacaaacgcg      300

gcaaaguaaa aggcacccaa gaaaugaaaa acaacuacaa caucauggaa auccgcacag      360

ucgccgucgg cauagucgca aucaaaggcg ucgaauccga auuuuaccuc gccaugaaca      420

aagaaggcaa acucuacgcc aaaaaagaau gcaacgaaga cugcaacuuc aaagaacuca      480

uccucgaaaa ccacuacaac accuacgccu ccgccaaaug gacccacaac ggcggcgaaa      540

uguucgucgc ccucaaccaa aaaggcaucc ccguccgcgg caaaaaaacc aaaaaagaac      600

aaaaaaccgc ccacuuccuc cccauggcca ucaccuaagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  5918
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt11)

<400>  5918
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaag       60

ccccccgcga acuagccgua ggcaucgacc ucggcacaac cuacagcugu gucggcguau      120

uccaacaagg cagaguagaa auccuagcca acgaccaagg caacagaacg accccaucau      180

acgucgcguu caccgacaca gaaaggcuag uaggagacgc agcaaaaucc caagcagccc      240

uaaacccgca caacacugua uucgacgcca aacgccuaau cggacgaaaa uucgcagaca      300

caaccgucca aucagacaug aaacacuggc cauuccaagu cgucuccgaa gguggaaaac      360

ccaaaguacg aguaugcuac cgaggggaag acaaaacauu cuacccagaa gaaauaagcu      420

caaugguacu aagcaaaaug aaagaaaccg cggaagccua ccuaggccaa ccaguaaaac      480

acgccguaau cacggucccg accuacuuca gcaacuccca gagacaggcc accaaagacg      540

caggagcaau cgcaggccua aaaguacucc caaucauaaa cgaagccaca gccgcagcaa      600

uagccuacgg ccuggaccga agaggagccg gcaaacgaaa cguacucaua uucgaccuag      660

gaggaggaac auucgacgua uccguacucu cgaucgacgc cggggucuuc gaaguaaaag      720

cuaccgccgg cgacacccac cuaggaggcg aagacuucga caaccgccua gucaaccacu      780

ucauggaaga auuucgcaga aaacacggca aagaccuaag cggaaacaaa cgagcccuca      840

gacgacuccg aacagccugc gaacgagcca aacgcacccc aucaagcagc acccaggcca      900

cacuagaaau cgacucccua uucgaaggcg uagacuucua caaaagcauc accagagcca      960

gauucgaaga acucugcagc gaccuauucc gaagcacccu agaacccgug gaaaaagccc     1020

uccgcgacgc caaacuagac aaagcacaaa uccacgacuu cguacuaggc ggcgggcucc     1080

acagccaccc acaaggcgca gaagucgccg caggccuacu ccaacgacaa ggcgcagaac     1140

aagaacacca gccauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  5919
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt11)

<400>  5919
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

aagaagugca ccacggggaa gaggaagucg aaaccuucgc cuuccaggcc gagauagccc      120

aacucaugag cuuaaucaua aacaccuucu acuccaacaa agaaaucuuc cucagagagu      180

ugauaucaaa cgcaagcgac gcccuggaca agauaagaua cgaaagccua acagacccau      240

caaaacugga cucaggaaag gaguuaaaaa uagacaucau cccaaaccca caagaacgca      300

cgcucacccu cguggacacc ggaauaggaa ugacaaaagc cgaccucaua aacaaucucg      360

gcacgauagc caagagcggg acaaaagccu ucauggaggc ccuacaagca ggagccgaca      420

uaagcaugau cggacaauuc ggcguaggcu ucuacagcgc auaccucguc gccgaaaagg      480

ugguaguaau cacaaaacac aacgacgacg aacaauacgc cugggaaagc agcgccggcg      540

ggagcuucac agucagagca gaccacggcg aaccuauagg acgcgggacu aaaguaaucc      600

uccaccuaaa ggaagaccaa accgaauacu uagaagaacg cagggucaag gaagucguca      660

aaaaacacag ccaguucauc ggcuacccca uaacccucua ccuggaaaaa gagagggaaa      720

aggaaauaag ugacgacgag gccgaggaag aaaaaggaga aaaagaagaa gaagacaaag      780

acgacgaaga aaagcccaag aucgaagacg uaggaagcga cgaagaagac gacucaggaa      840

aggacaagaa aaaaaaaacg aaaaaaauca aagagaaaua caucgaccaa gaagaacuga      900

acaaaacaaa accaaucugg accaggaacc ccgaugacau cacacaagaa gaauacgggg      960

aauuuuacaa aucgcuaaca aacgacuggg aggaccaccu cgcgguaaag cacuucagcg     1020

uggaaggaca acucgaauuu agagcacuac uauucauccc aaggagagcg ccauucgacc     1080

uguucgaaaa caagaaaaaa aaaaacaaca uaaagcuaua cguccgacga gucuucauaa     1140

uggacucaug cgacgaacug aucccagaau accuaaacuu cauccggggc guaguagacu     1200

ccgaagaccu cccacucaac aucagccgag aaaugcuaca acagagcaag auacugaaag     1260

ugaucagaaa aaacaucgua aaaaagugcc uagaacuauu cagcgaauua gcagaggaua     1320

aagaaaacua caagaaauuc uacgaagccu ucagcaagaa ccuaaaacug ggcauacacg     1380

aagacagcac caaucgaagg cgccuaagcg aacuacuaag auaccacaca agucagagcg     1440

gcgacgagau gacgagccua uccgaauacg uuagccggau gaaagaaacg caaaagucaa     1500

uauacuacau caccggagag agcaaggaac aaguagcgaa cucggcauuc gucgaacgcg     1560

ugcgaaagcg cggauucgaa gucguauaca ugacggagcc caucgacgag uacuguguac     1620

aacagcucaa agaauuugac ggcaaaagcc uagucucagu aaccaaagaa ggacuagaau     1680

ugcccgaaga cgaagaagag aagaaaaaaa uggaagaauc aaaagccaaa uucgagaacu     1740

ugugcaagcu gaugaaagag auccuagaca aaaagguaga aaaggucacg aucucaaacc     1800

ggcuggugag cucgcccugc ugcaucguca cgagcacaua cggcuggaca gcaaacaugg     1860

aacgaauaau gaaagcacaa gcccucagag acaacucaac caugggguac augauggcca     1920

agaaacaccu cgaaauaaac cccgaccacc cuauaguaga aacgcucagg caaaaggccg     1980

aagcagacaa aaacgacaaa gccguaaaag accucguggu ccugcucuuu gaaacagccc     2040

uacucucaag cggauuuuca cuggaggacc cacaaaccca cagcaacaga aucuaccgaa     2100

ugauuaagcu cggacugggu auugacgagg acgaaguagc cgcggaagaa cccaacgcgg     2160

caguccccga cgaaaucccg ccccuggaag gggacgagga cgcaucaaga auggaagagg     2220

ucgacuaggg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  5920
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt11)

<400>  5920
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

ccuucuccac cuccgccuuc ggccccgucg ccuucucccu cggccuccua cucguacucc      120

ccgccgccuu cccagccccc guccccccag gcgaagacuc caaagacguc gccgcccccc      180

accgccaacc ucucaccuca uccgaacgca ucgacaaaca aauacgcuac auccucgacg      240

gcaucuccgc ccuccgcaaa gaaaccugca acaaaucaaa caugugcgaa uccucaaaag      300

aagcccucgc cgaaaacaac cuaaaccucc ccaaaauggc cgaaaaagac ggcugcuucc      360

aauccggcuu caacgaagaa acaugccucg ucaaaauaau caccggacuc cucgaauuug      420

aagucuaccu cgaauaccua caaaaccgcu ucgaaucauc cgaagaacaa gcccgcgccg      480

uccaaauguc aaccaaaguc cucauccaau uccuccaaaa aaaagccaaa aaccucgacg      540

ccaucacaac ccccgacccc accaccaacg ccucccuacu caccaaacuc caagcccaaa      600

accaauggcu ccaagacaug accacccacc ucauccuccg cuccuucaaa gaauuucucc      660

aauccucccu ccgcgcccuc cgacaaaugu agggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  5921
<211>  1798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt11)

<400>  5921
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ccggcguacu cgcagccuuc cuauuccuau ccuggaccca cugccgcgca uuaccccucc      120

ccucaggagg cgaugaagac gaccuuuccg aagaagaccu gcaauucgcc gaacgcuacc      180

uccgauccua cuaccacccc accaaccucg ccggcauacu caaagaaaac gcagccucau      240

ccaugacaga acgccuccgc gaaaugcaau ccuucuuugg ccucgaaguc accggaaaac      300

uugacgacaa cacgcuagac gucaugaaaa aacccagaug cggagucccc gacgucggcg      360

aauacaacgu cuuccccaga acccuaaaau ggucaaaaau gaaccucacc uacagaauag      420

ucaacuacac cccugacaug acccacuccg aaguagaaaa agccuucaaa aaagccuuca      480

aagucugguc ugacguuacc ccccucaacu ucacccgacu ccacgacggc aucgccgaca      540

uaaugaucuc cuucggaauc aaagaacacg gcgacuucua ccccuucgac ggaccaucag      600

gccuacucgc ccacgccuuc ccaccaggac ccaacuacgg aggcgacgcc cacuucgaug      660

acgacgaaac cuggaccucc uccuccaaag gcuacaaccu cuuccuagua gccgcacacg      720

aauuuggcca cucacuagga cuagaccacu ccaaagaccc cggcgcucuu auguucccca      780

ucuacaccua cacugggaaa ucccacuuca ugcuccccga cgacgacgua caaggcaucc      840

aaagccucua cggcccgggc gacgaagauc ccaaccccaa acaccccaaa acaccagaca      900

aaugcgaccc cucacuauca cuagacgcaa ucaccucccu ccguggcgaa acuaugaucu      960

ucaaagaccg auucuucugg cgcuuacacc cccaacaagu cgacgccgaa cucuuccuua     1020

ccaaaucauu cuggcccgaa cuccccaacc gcaucgacgc cgccuacgaa caccccagcc     1080

augaccucau cuuuaucuuc cgcgggagaa aauucugggc acuaaacgga uacgacauac     1140

ucgaaggcua cccaaaaaaa aucuccgaac uaggccuccc aaaggaaguc aaaaagaucu     1200

ccgcagcagu acacuucgaa gacaccggca aaacccuccu auucucaggu aaccaaguau     1260

ggcgcuacga cgacaccaac cacaucaugg acaaagacua cccccgccuc aucgaagaag     1320

acuuccccgg cauaggcgac aaagucgacg ccgucuauga aaaaaacggc uacauauacu     1380

ucuuuaacgg ccccauccaa uuugaauacu ccauaugguc caaccgcauc guacgcguua     1440

ugccagccaa cuccauccuc uggugcuaag gacuagugca ucacauuuaa aagcaucuca     1500

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1560

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1620

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1740

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1798


<210>  5922
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt11)

<400>  5922
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

gccuaaucuu cgucuacacc cuaaucugcg ccaacuucug cuccugccga gacaccuccg      120

ccaccccaca auccgccucc auaaaagcac uccggaaugc caacuuacgc cgggacgacc      180

uauaccgucg agacgaaaca auccaaguaa aaggaaacgg cuacgugcaa ucgccccgau      240

ucccaaacuc cuacccacgc aaccuccucc ucaccuggcg acuacacucc caagaaaaca      300

cucgcaucca acucgucuuc gacaaccagu ucggccugga agaagccgaa aacgacaucu      360

gccgcuacga cuucgucgaa gucgaagaca uaucagaaac cuccaccauc auacgcggcc      420

gcuggugcgg ccacaaagag guaccccccc gcaucaaauc ccgcacaaac caaaucaaaa      480

uaaccuucaa aucagacgac uacuucguag cuaaacccgg auucaaaauc uacuacuccc      540

uccuagaaga cuuccaaccc gccgcagcau ccgagaccaa cugggaaucc guaaccuccu      600

ccauauccgg cguauccuac aacagccccu ccgucacaga ccccacccuu auagccgacg      660

cccucgacaa aaaaaucgcc gaauuugaca ccgucgaaga ucuccuaaaa uacuucaacc      720

ccgaaucaug gcaagaagac cucgaaaaca uguaccuaga caccccacga uaccgcggac      780

gcucauacca cgaccgaaaa uccaaagucg accucgaccg acucaacgac gacgccaaac      840

gcuacagcug cacaccacgc aacuacuccg ucaacauccg cgaagaacua aaacucgcca      900

acguagucuu cuucccccgc ugccuucucg uccaaagaug cggcggcaac ugcggcugug      960

gaaccguaaa cuggcgcagc ugcaccugua acucaggcaa aaccgucaaa aaauaccacg     1020

aaguccucca auucgaacca ggccacauca aacgccgcgg ccgagccaaa acaauggccc     1080

ucgucgacau ccagcucgac caccacgaac gcugcgacug cauaugcucc agccgccccc     1140

cucgcuaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  5923
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt11)

<400>  5923
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguca       60

cccacuccaa auucccugcc gcaggcaugu cccgaccccu cgacaccucc cuccgacuca      120

aaaccuucuc cucaaagucc gaauaccaac ucgucgucaa cgccguccgu aaacuccaag      180

aauccggcuu cuacuggucc gccgucaccg guggugaagc aaaccuccuc cucuccgcag      240

aacccgccgg caccuuccuc auccgcgacu ccucagacca acgccacuuc uucacccucu      300

cagucaaaac ccaauccggc accaaaaacc uccgcaucca augcgaaggc ggcuccuucu      360

cccuccaauc cgacccacgc uccacacaac cugucccacg cuucgacugc guccucaaac      420

ucguccacca cuacaugcca ccccccggcg cccccuccuu cccauccccc cccaccgaac      480

ccuccucaga aguccccgaa caacccucag cccaaccccu ccccggcucc cccccccgcc      540

gcgcauacua caucuacucc ggcggcgaaa aaaucccacu cguacucucc cgcccccucu      600

ccuccaacgu cgccacccua caacaccucu gccgcaaaac cgucaacggc caccucgacu      660

ccuacgaaaa agucacccaa cuacccggcc ccauccgcga auuucucgac caauacgaug      720

caccccuaua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  5924
<211>  865
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt11)

<400>  5924
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggucc       60

ccuccgccgg ccaacucgcc cuauucgccc ucggaaucgu ccucgcagcc ugccaagccc      120

ucgaaaacuc caccuccccc cucuccgccg acccccccgu cgccgccgcc gucgucuccc      180

acuucaacga cugccccgac ucccacaccc aauucugcuu ccacggcacc ugucgcuucc      240

ucguccaaga agacaaaccc gccugcgucu gccacuccgg cuacgucggc gcccgcugcg      300

aacacgccga ccuccucgcc gucgucgccg ccucccaaaa aaaacaagcc aucaccgccc      360

ucgucgucgu cuccaucguc gcccucgccg uccucaucau caccuguguc cuaauccacu      420

gcugccaagu ccgcaaacac ugcgaauggu gccgcgcccu caucugccgc cacgaaaaac      480

ccuccgcccu ccucaaaggc cgcaccgccu gcugccacuc cgaaacaguc guuuaaggac      540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa      840

ggcucuuuuc agagccacca gaauu                                            865


<210>  5925
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt11)

<400>  5925
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugcguccu cuccgccuuc cucauauuac accucgucac cguugcccua ucccucucga      120

cuugcuccac ccucgacaug gaccaauuca ugcgcaaaag aaucgaagca auccgaggcc      180

aaauccucuc aaaacucaaa cuuacauccc ccccugaaga cuauccagaa cccgaggaag      240

uccccccuga agucauaucc auauacaaca gcacccgcga ccuacuccaa gaaaaagccu      300

cgcgacgagc cgcagccugc gaacgcgaac gcagcgacga agaauacuac gccaaggaag      360

ucuacaaaau cgacaugccg cccuucuucc caucagagaa ugcuaucccc cccaccuucu      420

accgaccaua cuuccgcauc guccgcuucg acgucuccgc aauggaaaaa aacgccucca      480

accucgucaa agccgaauuu cgcgucuucc gccugcaaaa ccccaaagcc cgcguucccg      540

aacaacgcau cgaacucuac caaauacuca aauccaaaga ccucaccucu cccacccaac      600

guuacaucga cucuaaagua gucaaaacac gcgccgaagg cgaauggcuc uccuucgacg      660

uaaccgacgc cguacacgaa uggcuccacc acaaagacag aaaccucgga uucaaaaucu      720

cccuacacug ccccugcugc acuuucgucc ccuccaacaa cuacauaauu cccaacaaau      780

ccgaagaacu ugaagcccgc uucgccggca ucgacggaac cucgaccuac acuucaggcg      840

accagaaaac cauuaaaucc acccgcaaaa aaaacucggg caaaacaccc caccuccuac      900

ucaugcuccu cccauccuac cggcuagaau cccaacaaac caaccgacgc aaaaaacgag      960

cccucgacgc agccuacugc uuccguaacg uccaagacaa uugcugccua cgcccacucu     1020

acaucgauuu caaacgugac cucggaugga aauggaucca ugaacccaaa ggcuacaacg     1080

ccaacuucug cgcaggcgca ugccccuacc ucuggagcuc cgacacccaa cacucccgcg     1140

uccuaagccu uuacaacacc aucaaccccg aagccucagc cucccccugc ugcgucuccc     1200

aagaccucga accacuaaca auccucuacu acaucggcaa aacccccaaa auagaacaac     1260

ucuccaacau gaucgucaaa uccugcaaau gcuccuaagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  5926
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt11)

<400>  5926
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcac       60

cagucgcagu cugggccgcc cucgccguag gccuugaacu cugggcagcc gcccacgccc      120

ucccagcaca agucgcauuc acucccuacg cacccgaacc cggcuccacc ugucgccuac      180

gcgaauacua ugaccaaaca gcacaaaugu gcugcuccaa augcucuccc ggccaacacg      240

cuaaaguauu cugcacaaaa accucugaca ccguaugcga cucaugcgaa gacuccacau      300

auacccaacu cuggaacugg guccccgaau gccucuccug cggcucccgc ugcagcucag      360

accaaguaga aacccaagca ugcacccgcg agcaaaaccg caucugcaca ugccgccccg      420

gcugguacug cgcucucucc aaacaagaag gcugcagacu uugugcaccu cugaggaaau      480

gccgaccagg cuuuggugua gcaagacccg guaccgaaac cucagacguc gucugcaaac      540

cgugugcacc cggcaccuuc ucaaacacca ccuccucuac cgacaucugc cgaccacauc      600

aaaucugcaa cguagucgcc aucccaggca acgccuccau ggacgccgua ugcaccucga      660

ccucccccac ccgcuccaug gcccccggcg ccguacaccu accccaaccc gucuccaccc      720

gaucccagca cacccaaccc accccagaac ccagcaccgc cccgucaacc ucauuccuac      780

ucccaauggg ccccucccca cccgcagaag gcuccacagg cgauuucgcc cuccccguag      840

gacuaauagu uggcgucacc gcccuaggcc uccuuaucau cggcguaguc aacugcguca      900

ucaugaccca agucaaaaaa aaaccccucu gccuccaacg cgaagccaaa gucccacacc      960

ucccagccga caaagcccgc ggaacccaag gccccgaaca acaacaccuc cucaucaccg     1020

cccccucauc aagcuccucc ucacucgaau cauccgccuc cgcccucgau cgacgcgccc     1080

ccacacgcaa ccaaccacaa gccccaggcg uagaagcguc cggcgccggc gaagcccgcg     1140

ccuccaccgg cucguccgac uccucaccag gaggucacgg cacccaagua aaugucaccu     1200

guaucgugaa cguuuguucc uccucagauc acagcuccca auguucuucc caagccuccu     1260

ccacaauggg cgacaccgau uccagccccu cagaaucccc caaagacgaa caagucccau     1320

ucucaaaaga agagugugcc uuccgauccc agcucgaaac accagaaacc cuacucgguu     1380

caaccgaaga aaaaccccuc ccccucggcg ucccagacgc aggcaugaaa cccuccuaag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  5927
<211>  1081
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt11)

<400>  5927
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

uccuccuaag cuggguccac uggucccucg cccuacuccu cuaccuacac cacgccaaau      120

ggucccaagc cgcacccaug gccgaaggcg gcggccaaaa ccaccacgaa gucgucaaau      180

ucauggacgu cuaccaacgc ucauacugcc accccaucga aacccucguc gacaucuucc      240

aagaauaccc cgacgaaaua gaauacaucu ucaaacccuc augcgucccc cucaugcgcu      300

gcggcggcug cugcaacgac gaaggacucg aaugcguacc caccgaagaa ucaaacauca      360

caaugcaaau caugcgcauc aaaccccacc aaggccaaca caucggcgaa auguccuucc      420

uccaacacaa caaaugcgaa ugccgcccca aaaaagaccg agcacgacaa gaaaaaaaau      480

ccguccgagg caaaggcaaa ggccaaaaac gaaaaagaaa aaaaucccgc uacaaauccu      540

gguccguaua cgucggcgcc cgaugcugcc ucaugccaug gucccucccc ggcccccacc      600

caugcggccc cugcuccgaa cgccgcaaac accucuucgu ccaagacccc caaaccugca      660

aaugcuccug caaaaacacc gacuccagau gcaaagcccg ccaacucgaa cucaacgaac      720

gcaccugucg cugcgacaaa ccccgacgcu aaggacuagu gcaucacauu uaaaagcauc      780

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      840

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      900

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1020

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1080

u                                                                     1081


<210>  5928
<211>  1006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt11)

<400>  5928
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguccc       60

cccuccuccg ccgccuccuc cucgcagccc uacuccaacu agcccccgca caagcccccg      120

ucucccaacc cgacgccccc ggccaccaac gcaaaguagu cuccuggaua gacgucuaca      180

cccgcgccac cugucaaccc cgcgaagucg uagucccccu cacagucgaa cucaugggca      240

cagucgccaa acaacucgua cccucaugcg ucaccgucca aagaugcggc ggcugcugcc      300

ccgacgacgg ccucgaaugc guccccaccg gccaacacca aguccgcaug caaauacuca      360

ugauccgaua cccaucaucc caacuaggag aaaugucacu cgaagaacac ucucaaugcg      420

aaugcagacc caaaaaaaaa gacucagccg uaaaaccaga ccgcgccgca acaccccacc      480

accgccccca accacgauca guccccggcu gggacuccgc ccccggcgcc cccucccccg      540

ccgacaucac ccaccccacc cccgcccccg gcccauccgc ccacgccgcc cccuccacca      600

ccucugcccu aacccccggc cccgccgccg ccgccgcaga cgccgccgcc ucauccgucg      660

ccaaaggcgg cgccuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc      960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1006


<210>  5929
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt11)

<400>  5929
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgccggca cccguugccu ccuugcccuc cuccuacccc      120

aaguccuacu aggcggagca gccggccucg uccccgaacu cggccgccgc aaauucgccg      180

ccgccucauc cggacgcccc uccucacaac ccagcgacga aguacucuca gaauuugaac      240

uucgucuacu cuccauguuc ggccucaaac aacgacccac ucccucccgc gacgcagucg      300

uccccccuua caugcuagac cuuuaccgcc gccacuccgg ccaacccgga ucacccgccc      360

ccgaccaucg ccucgaaaga gccgccuccc gagccaauac cguccgcuca uuccaccacg      420

aagaaucacu cgaagaacua cccgaaacca gcggaaaaac aacacgcaga uucuucuuca      480

accucuccag cauccccacc gaagaauuua ucaccuccgc cgaacuacaa guauucagag      540

aacaaaugca ggacgcccuc ggcaacaacu ccagcuucca ccaccgcauc aacauauacg      600

aaauaaucaa acccgccaca gcuaacucca aguuccccgu cacacgccua cucgacaccc      660

gccuagucaa ccaaaaugcc ucccgcuggg aauccuucga cgucaccccc gccgucaugc      720

gauggaccgc acaaggccac gccaaucacg gcuucgucgu agaaguugca caccuagaag      780

aaaaacaagg cgucuccaaa cgccacgucc gcaucuccag aucccuacac caagacgaac      840

acucaugguc ccaaauccgc ccccuccuag ucaccuucgg acaugacggc aaaggacacc      900

cgcuccacaa acgcgaaaaa cgccaagcca aacacaaaca acgcaaacgc cucaaaucau      960

ccugcaaacg ccacccacuc uacguagacu ucuccgacgu aggauggaac gacuggauag     1020

ucgcaccccc aggcuaccac gcauucuacu gccacggaga augcccauuc ccacuugccg     1080

accaccucaa cuccaccaac cacgcuaucg uacaaacacu cgucaacucc gucaacucaa     1140

aaaucccaaa agcaugcugc guccccacag aacucucagc caucuccaug cucuaccucg     1200

acgaaaacga aaaggucguc cuaaaaaacu accaagacau ggucgucgaa ggcugcggcu     1260

gccgcuaggg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  5930
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt11)

<400>  5930
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacguccgau cacuacgcgc cgcagcccca cacuccuucg      120

uagcacucug ggcaccccua uucuuacucc gcuccgcacu agccgacuuc ucccucgaca      180

acgaagucca cucgagcuuc auccaccgcc gccuacgguc ccaagaaaga cgcgaaaugc      240

aacgcgaaau ccucucaauu cuaggacucc cccaccgccc ccgcccccac cuccaaggca      300

aacacaacuc ugcccccaug uucaugcucg accucuacaa cgccauggca guagaagaag      360

gaggcggacc cggcggccaa ggcuucucau accccuacaa agccguuuuc ucaacccaag      420

gcccgccccu cgcaucccuc caagacucac acuuccuaac cgacgccgac augguaaugu      480

cauucgucaa ccucguagaa caugacaaag aauuuuucca cccccgcuau caccaccgcg      540

aauuucgauu cgaccucucg aaaauacccg aaggcgaagc cgugaccgca gccgaauuuc      600

gcauauacaa agacuacauc cgcgaacgcu ucgacaacga aacauuccgc aucuccgucu      660

accaagugcu ccaagaacac cucggccgcg aaagcgaccu cuuccuacuu gacucccgca      720

cacuuugggc cucugaagaa gguuggcucg uauucgacau aacagccacc ucaaaccacu      780

ggguagucaa cccccgucac aaccuaggac uccagcuauc aguagaaaca cucgacggcc      840

agagcaucaa ccccaaacuu gcgggacuca ucggccgcca cggaccacaa aacaagcagc      900

ccuucauggu cgccuucuuu aaagccaccg aaguacauuu cagauccaua cgcuccaccg      960

gguccaaaca acgaucacaa aaccgaucca aaaccccaaa aaaccaagaa gcucuacgaa     1020

uggcaaacgu agcugaaaac agcuccucag accaacgcca agccugcaaa aaacacgaac     1080

ucuacgucuc cuuccgagac cucggcuggc aagacuggau caucgcccca gaaggcuacg     1140

cagcauacua cugcgaaggc gaaugcgccu ucccccuuaa cucuuacaug aacgccacca     1200

accacgcaau cguccagacc cucguacacu ucaucaaccc cgaaacuguc cccaaacccu     1260

gcugcgcccc cacccaauua aacgcaaucu ccguccucua cuucgacgac uccucgaacg     1320

ucauacucaa aaaauaccga aacauggucg uccgcgccug cggcugccau uaaggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  5931
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt11)

<400>  5931
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagccuccg ccgcccuccu cugccuccuc cucaccgccg      120

ccgccuucuc cccccaaggc cuagcccaac ccgucggcau caacaccucc accaccuguu      180

gcuaccgauu caucaacaaa aaaaucccca aacaacgccu cgaauccuac cgccgcacca      240

ccuccucaca cugcccccgc gaagccguca ucuucaaaac caaacucgac aaagaaaucu      300

gcgccgaccc cacccaaaaa uggguccaag acuucaugaa acaccucgac aaaaaaaccc      360

aaacccccaa acucuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  5932
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt11)

<400>  5932
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uccucaccug gauccucccc acccuccucu      120

accgcuccug cuuccacauc aucugccucg ucggcaccau cucccucgcc ugcaacgaca      180

ugacccccga acaaauggcc acaaacguca acugcuccuc ccccgaacgc cacacccgcu      240

ccuacgacua cauggaaggc ggcgacaucc gcguccgccg acucuucugc cgcacccaau      300

gguaccuacg caucgacaaa cgcggcaaag uaaaaggcac ccaagaaaug aaaaacaacu      360

acaacaucau ggaaauccgc acagucgccg ucggcauagu cgcaaucaaa ggcgucgaau      420

ccgaauuuua ccucgccaug aacaaagaag gcaaacucua cgccaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa cucauccucg aaaaccacua caacaccuac gccuccgcca      540

aauggaccca caacggcggc gaaauguucg ucgcccucaa ccaaaaaggc auccccgucc      600

gcggcaaaaa aaccaaaaaa gaacaaaaaa ccgcccacuu ccuccccaug gccaucaccu      660

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  5933
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt11)

<400>  5933
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcccccc gcgaacuagc cguaggcauc gaccucggca      120

caaccuacag cugugucggc guauuccaac aaggcagagu agaaauccua gccaacgacc      180

aaggcaacag aacgacccca ucauacgucg cguucaccga cacagaaagg cuaguaggag      240

acgcagcaaa aucccaagca gcccuaaacc cgcacaacac uguauucgac gccaaacgcc      300

uaaucggacg aaaauucgca gacacaaccg uccaaucaga caugaaacac uggccauucc      360

aagucgucuc cgaaggugga aaacccaaag uacgaguaug cuaccgaggg gaagacaaaa      420

cauucuaccc agaagaaaua agcucaaugg uacuaagcaa aaugaaagaa accgcggaag      480

ccuaccuagg ccaaccagua aaacacgccg uaaucacggu cccgaccuac uucagcaacu      540

cccagagaca ggccaccaaa gacgcaggag caaucgcagg ccuaaaagua cucccaauca      600

uaaacgaagc cacagccgca gcaauagccu acggccugga ccgaagagga gccggcaaac      660

gaaacguacu cauauucgac cuaggaggag gaacauucga cguauccgua cucucgaucg      720

acgccggggu cuucgaagua aaagcuaccg ccggcgacac ccaccuagga ggcgaagacu      780

ucgacaaccg ccuagucaac cacuucaugg aagaauuucg cagaaaacac ggcaaagacc      840

uaagcggaaa caaacgagcc cucagacgac uccgaacagc cugcgaacga gccaaacgca      900

ccccaucaag cagcacccag gccacacuag aaaucgacuc ccuauucgaa ggcguagacu      960

ucuacaaaag caucaccaga gccagauucg aagaacucug cagcgaccua uuccgaagca     1020

cccuagaacc cguggaaaaa gcccuccgcg acgccaaacu agacaaagca caaauccacg     1080

acuucguacu aggcggcggg cuccacagcc acccacaagg cgcagaaguc gccgcaggcc     1140

uacuccaacg acaaggcgca gaacaagaac accagccaua aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  5934
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt11)

<400>  5934
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaagaag ugcaccacgg ggaagaggaa gucgaaaccu      120

ucgccuucca ggccgagaua gcccaacuca ugagcuuaau cauaaacacc uucuacucca      180

acaaagaaau cuuccucaga gaguugauau caaacgcaag cgacgcccug gacaagauaa      240

gauacgaaag ccuaacagac ccaucaaaac uggacucagg aaaggaguua aaaauagaca      300

ucaucccaaa cccacaagaa cgcacgcuca cccucgugga caccggaaua ggaaugacaa      360

aagccgaccu cauaaacaau cucggcacga uagccaagag cgggacaaaa gccuucaugg      420

aggcccuaca agcaggagcc gacauaagca ugaucggaca auucggcgua ggcuucuaca      480

gcgcauaccu cgucgccgaa aaggugguag uaaucacaaa acacaacgac gacgaacaau      540

acgccuggga aagcagcgcc ggcgggagcu ucacagucag agcagaccac ggcgaaccua      600

uaggacgcgg gacuaaagua auccuccacc uaaaggaaga ccaaaccgaa uacuuagaag      660

aacgcagggu caaggaaguc gucaaaaaac acagccaguu caucggcuac cccauaaccc      720

ucuaccugga aaaagagagg gaaaaggaaa uaagugacga cgaggccgag gaagaaaaag      780

gagaaaaaga agaagaagac aaagacgacg aagaaaagcc caagaucgaa gacguaggaa      840

gcgacgaaga agacgacuca ggaaaggaca agaaaaaaaa aacgaaaaaa aucaaagaga      900

aauacaucga ccaagaagaa cugaacaaaa caaaaccaau cuggaccagg aaccccgaug      960

acaucacaca agaagaauac ggggaauuuu acaaaucgcu aacaaacgac ugggaggacc     1020

accucgcggu aaagcacuuc agcguggaag gacaacucga auuuagagca cuacuauuca     1080

ucccaaggag agcgccauuc gaccuguucg aaaacaagaa aaaaaaaaac aacauaaagc     1140

uauacguccg acgagucuuc auaauggacu caugcgacga acugauccca gaauaccuaa     1200

acuucauccg gggcguagua gacuccgaag accucccacu caacaucagc cgagaaaugc     1260

uacaacagag caagauacug aaagugauca gaaaaaacau cguaaaaaag ugccuagaac     1320

uauucagcga auuagcagag gauaaagaaa acuacaagaa auucuacgaa gccuucagca     1380

agaaccuaaa acugggcaua cacgaagaca gcaccaaucg aaggcgccua agcgaacuac     1440

uaagauacca cacaagucag agcggcgacg agaugacgag ccuauccgaa uacguuagcc     1500

ggaugaaaga aacgcaaaag ucaauauacu acaucaccgg agagagcaag gaacaaguag     1560

cgaacucggc auucgucgaa cgcgugcgaa agcgcggauu cgaagucgua uacaugacgg     1620

agcccaucga cgaguacugu guacaacagc ucaaagaauu ugacggcaaa agccuagucu     1680

caguaaccaa agaaggacua gaauugcccg aagacgaaga agagaagaaa aaaauggaag     1740

aaucaaaagc caaauucgag aacuugugca agcugaugaa agagauccua gacaaaaagg     1800

uagaaaaggu cacgaucuca aaccggcugg ugagcucgcc cugcugcauc gucacgagca     1860

cauacggcug gacagcaaac auggaacgaa uaaugaaagc acaagcccuc agagacaacu     1920

caaccauggg guacaugaug gccaagaaac accucgaaau aaaccccgac cacccuauag     1980

uagaaacgcu caggcaaaag gccgaagcag acaaaaacga caaagccgua aaagaccucg     2040

ugguccugcu cuuugaaaca gcccuacucu caagcggauu uucacuggag gacccacaaa     2100

cccacagcaa cagaaucuac cgaaugauua agcucggacu ggguauugac gaggacgaag     2160

uagccgcgga agaacccaac gcggcagucc ccgacgaaau cccgccccug gaaggggacg     2220

aggacgcauc aagaauggaa gaggucgacu agggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  5935
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt11)

<400>  5935
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccaccuccgc cuucggcccc gucgccuucu      120

cccucggccu ccuacucgua cuccccgccg ccuucccagc ccccgucccc ccaggcgaag      180

acuccaaaga cgucgccgcc ccccaccgcc aaccucucac cucauccgaa cgcaucgaca      240

aacaaauacg cuacauccuc gacggcaucu ccgcccuccg caaagaaacc ugcaacaaau      300

caaacaugug cgaauccuca aaagaagccc ucgccgaaaa caaccuaaac cuccccaaaa      360

uggccgaaaa agacggcugc uuccaauccg gcuucaacga agaaacaugc cucgucaaaa      420

uaaucaccgg acuccucgaa uuugaagucu accucgaaua ccuacaaaac cgcuucgaau      480

cauccgaaga acaagcccgc gccguccaaa ugucaaccaa aguccucauc caauuccucc      540

aaaaaaaagc caaaaaccuc gacgccauca caacccccga ccccaccacc aacgccuccc      600

uacucaccaa acuccaagcc caaaaccaau ggcuccaaga caugaccacc caccucaucc      660

uccgcuccuu caaagaauuu cuccaauccu cccuccgcgc ccuccgacaa auguagggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  5936
<211>  1763
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt11)

<400>  5936
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg uacucgcagc cuuccuauuc cuauccugga      120

cccacugccg cgcauuaccc cuccccucag gaggcgauga agacgaccuu uccgaagaag      180

accugcaauu cgccgaacgc uaccuccgau ccuacuacca ccccaccaac cucgccggca      240

uacucaaaga aaacgcagcc ucauccauga cagaacgccu ccgcgaaaug caauccuucu      300

uuggccucga agucaccgga aaacuugacg acaacacgcu agacgucaug aaaaaaccca      360

gaugcggagu ccccgacguc ggcgaauaca acgucuuccc cagaacccua aaauggucaa      420

aaaugaaccu caccuacaga auagucaacu acaccccuga caugacccac uccgaaguag      480

aaaaagccuu caaaaaagcc uucaaagucu ggucugacgu uaccccccuc aacuucaccc      540

gacuccacga cggcaucgcc gacauaauga ucuccuucgg aaucaaagaa cacggcgacu      600

ucuaccccuu cgacggacca ucaggccuac ucgcccacgc cuucccacca ggacccaacu      660

acggaggcga cgcccacuuc gaugacgacg aaaccuggac cuccuccucc aaaggcuaca      720

accucuuccu aguagccgca cacgaauuug gccacucacu aggacuagac cacuccaaag      780

accccggcgc ucuuauguuc cccaucuaca ccuacacugg gaaaucccac uucaugcucc      840

ccgacgacga cguacaaggc auccaaagcc ucuacggccc gggcgacgaa gaucccaacc      900

ccaaacaccc caaaacacca gacaaaugcg accccucacu aucacuagac gcaaucaccu      960

cccuccgugg cgaaacuaug aucuucaaag accgauucuu cuggcgcuua cacccccaac     1020

aagucgacgc cgaacucuuc cuuaccaaau cauucuggcc cgaacucccc aaccgcaucg     1080

acgccgccua cgaacacccc agccaugacc ucaucuuuau cuuccgcggg agaaaauucu     1140

gggcacuaaa cggauacgac auacucgaag gcuacccaaa aaaaaucucc gaacuaggcc     1200

ucccaaagga agucaaaaag aucuccgcag caguacacuu cgaagacacc ggcaaaaccc     1260

uccuauucuc agguaaccaa guauggcgcu acgacgacac caaccacauc auggacaaag     1320

acuacccccg ccucaucgaa gaagacuucc ccggcauagg cgacaaaguc gacgccgucu     1380

augaaaaaaa cggcuacaua uacuucuuua acggccccau ccaauuugaa uacuccauau     1440

gguccaaccg caucguacgc guuaugccag ccaacuccau ccucuggugc uaaggacuag     1500

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1560

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1620

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1680

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaaaaaga auu                                             1763


<210>  5937
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt11)

<400>  5937
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgccuaa ucuucgucua cacccuaauc ugcgccaacu      120

ucugcuccug ccgagacacc uccgccaccc cacaauccgc cuccauaaaa gcacuccgga      180

augccaacuu acgccgggac gaccuauacc gucgagacga aacaauccaa guaaaaggaa      240

acggcuacgu gcaaucgccc cgauucccaa acuccuaccc acgcaaccuc cuccucaccu      300

ggcgacuaca cucccaagaa aacacucgca uccaacucgu cuucgacaac caguucggcc      360

uggaagaagc cgaaaacgac aucugccgcu acgacuucgu cgaagucgaa gacauaucag      420

aaaccuccac caucauacgc ggccgcuggu gcggccacaa agagguaccc ccccgcauca      480

aaucccgcac aaaccaaauc aaaauaaccu ucaaaucaga cgacuacuuc guagcuaaac      540

ccggauucaa aaucuacuac ucccuccuag aagacuucca acccgccgca gcauccgaga      600

ccaacuggga auccguaacc uccuccauau ccggcguauc cuacaacagc cccuccguca      660

cagaccccac ccuuauagcc gacgcccucg acaaaaaaau cgccgaauuu gacaccgucg      720

aagaucuccu aaaauacuuc aaccccgaau cauggcaaga agaccucgaa aacauguacc      780

uagacacccc acgauaccgc ggacgcucau accacgaccg aaaauccaaa gucgaccucg      840

accgacucaa cgacgacgcc aaacgcuaca gcugcacacc acgcaacuac uccgucaaca      900

uccgcgaaga acuaaaacuc gccaacguag ucuucuuccc ccgcugccuu cucguccaaa      960

gaugcggcgg caacugcggc uguggaaccg uaaacuggcg cagcugcacc uguaacucag     1020

gcaaaaccgu caaaaaauac cacgaagucc uccaauucga accaggccac aucaaacgcc     1080

gcggccgagc caaaacaaug gcccucgucg acauccagcu cgaccaccac gaacgcugcg     1140

acugcauaug cuccagccgc cccccucgcu aaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  5938
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt11)

<400>  5938
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccacu ccaaauuccc ugccgcaggc augucccgac      120

cccucgacac cucccuccga cucaaaaccu ucuccucaaa guccgaauac caacucgucg      180

ucaacgccgu ccguaaacuc caagaauccg gcuucuacug guccgccguc accgguggug      240

aagcaaaccu ccuccucucc gcagaacccg ccggcaccuu ccucauccgc gacuccucag      300

accaacgcca cuucuucacc cucucaguca aaacccaauc cggcaccaaa aaccuccgca      360

uccaaugcga aggcggcucc uucucccucc aauccgaccc acgcuccaca caaccugucc      420

cacgcuucga cugcguccuc aaacucgucc accacuacau gccacccccc ggcgcccccu      480

ccuucccauc cccccccacc gaacccuccu cagaaguccc cgaacaaccc ucagcccaac      540

cccuccccgg cucccccccc cgccgcgcau acuacaucua cuccggcggc gaaaaaaucc      600

cacucguacu cucccgcccc cucuccucca acgucgccac ccuacaacac cucugccgca      660

aaaccgucaa cggccaccuc gacuccuacg aaaaagucac ccaacuaccc ggccccaucc      720

gcgaauuucu cgaccaauac gaugcacccc uauaaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  5939
<211>  830
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt11)

<400>  5939
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guccccuccg ccggccaacu cgcccuauuc gcccucggaa      120

ucguccucgc agccugccaa gcccucgaaa acuccaccuc cccccucucc gccgaccccc      180

ccgucgccgc cgccgucguc ucccacuuca acgacugccc cgacucccac acccaauucu      240

gcuuccacgg caccugucgc uuccucgucc aagaagacaa acccgccugc gucugccacu      300

ccggcuacgu cggcgcccgc ugcgaacacg ccgaccuccu cgccgucguc gccgccuccc      360

aaaaaaaaca agccaucacc gcccucgucg ucgucuccau cgucgcccuc gccguccuca      420

ucaucaccug uguccuaauc cacugcugcc aaguccgcaa acacugcgaa uggugccgcg      480

cccucaucug ccgccacgaa aaacccuccg cccuccucaa aggccgcacc gccugcugcc      540

acuccgaaac agucguuuaa ggacuagugc aucacauuua aaagcaucuc agccuaccau      600

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug      660

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc      720

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                 830


<210>  5940
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt11)

<400>  5940
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uccucuccgc cuuccucaua uuacaccucg      120

ucaccguugc ccuaucccuc ucgacuugcu ccacccucga cauggaccaa uucaugcgca      180

aaagaaucga agcaauccga ggccaaaucc ucucaaaacu caaacuuaca ucccccccug      240

aagacuaucc agaacccgag gaaguccccc cugaagucau auccauauac aacagcaccc      300

gcgaccuacu ccaagaaaaa gccucgcgac gagccgcagc cugcgaacgc gaacgcagcg      360

acgaagaaua cuacgccaag gaagucuaca aaaucgacau gccgcccuuc uucccaucag      420

agaaugcuau cccccccacc uucuaccgac cauacuuccg caucguccgc uucgacgucu      480

ccgcaaugga aaaaaacgcc uccaaccucg ucaaagccga auuucgcguc uuccgccugc      540

aaaaccccaa agcccgcguu cccgaacaac gcaucgaacu cuaccaaaua cucaaaucca      600

aagaccucac cucucccacc caacguuaca ucgacucuaa aguagucaaa acacgcgccg      660

aaggcgaaug gcucuccuuc gacguaaccg acgccguaca cgaauggcuc caccacaaag      720

acagaaaccu cggauucaaa aucucccuac acugccccug cugcacuuuc guccccucca      780

acaacuacau aauucccaac aaauccgaag aacuugaagc ccgcuucgcc ggcaucgacg      840

gaaccucgac cuacacuuca ggcgaccaga aaaccauuaa auccacccgc aaaaaaaacu      900

cgggcaaaac accccaccuc cuacucaugc uccucccauc cuaccggcua gaaucccaac      960

aaaccaaccg acgcaaaaaa cgagcccucg acgcagccua cugcuuccgu aacguccaag     1020

acaauugcug ccuacgccca cucuacaucg auuucaaacg ugaccucgga uggaaaugga     1080

uccaugaacc caaaggcuac aacgccaacu ucugcgcagg cgcaugcccc uaccucugga     1140

gcuccgacac ccaacacucc cgcguccuaa gccuuuacaa caccaucaac cccgaagccu     1200

cagccucccc cugcugcguc ucccaagacc ucgaaccacu aacaauccuc uacuacaucg     1260

gcaaaacccc caaaauagaa caacucucca acaugaucgu caaauccugc aaaugcuccu     1320

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  5941
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt11)

<400>  5941
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaccagucg cagucugggc cgcccucgcc guaggccuug      120

aacucugggc agccgcccac gcccucccag cacaagucgc auucacuccc uacgcacccg      180

aacccggcuc caccugucgc cuacgcgaau acuaugacca aacagcacaa augugcugcu      240

ccaaaugcuc ucccggccaa cacgcuaaag uauucugcac aaaaaccucu gacaccguau      300

gcgacucaug cgaagacucc acauauaccc aacucuggaa cugggucccc gaaugccucu      360

ccugcggcuc ccgcugcagc ucagaccaag uagaaaccca agcaugcacc cgcgagcaaa      420

accgcaucug cacaugccgc cccggcuggu acugcgcucu cuccaaacaa gaaggcugca      480

gacuuugugc accucugagg aaaugccgac caggcuuugg uguagcaaga cccgguaccg      540

aaaccucaga cgucgucugc aaaccgugug cacccggcac cuucucaaac accaccuccu      600

cuaccgacau cugccgacca caucaaaucu gcaacguagu cgccauccca ggcaacgccu      660

ccauggacgc cguaugcacc ucgaccuccc ccacccgcuc cauggccccc ggcgccguac      720

accuacccca acccgucucc acccgauccc agcacaccca acccacccca gaacccagca      780

ccgccccguc aaccucauuc cuacucccaa ugggccccuc cccacccgca gaaggcucca      840

caggcgauuu cgcccucccc guaggacuaa uaguuggcgu caccgcccua ggccuccuua      900

ucaucggcgu agucaacugc gucaucauga cccaagucaa aaaaaaaccc cucugccucc      960

aacgcgaagc caaaguccca caccucccag ccgacaaagc ccgcggaacc caaggccccg     1020

aacaacaaca ccuccucauc accgcccccu caucaagcuc cuccucacuc gaaucauccg     1080

ccuccgcccu cgaucgacgc gcccccacac gcaaccaacc acaagcccca ggcguagaag     1140

cguccggcgc cggcgaagcc cgcgccucca ccggcucguc cgacuccuca ccaggagguc     1200

acggcaccca aguaaauguc accuguaucg ugaacguuug uuccuccuca gaucacagcu     1260

cccaauguuc uucccaagcc uccuccacaa ugggcgacac cgauuccagc cccucagaau     1320

cccccaaaga cgaacaaguc ccauucucaa aagaagagug ugccuuccga ucccagcucg     1380

aaacaccaga aacccuacuc gguucaaccg aagaaaaacc ccucccccuc ggcgucccag     1440

acgcaggcau gaaacccucc uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  5942
<211>  1046
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt11)

<400>  5942
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc uaagcugggu ccacuggucc cucgcccuac      120

uccucuaccu acaccacgcc aaaugguccc aagccgcacc cauggccgaa ggcggcggcc      180

aaaaccacca cgaagucguc aaauucaugg acgucuacca acgcucauac ugccacccca      240

ucgaaacccu cgucgacauc uuccaagaau accccgacga aauagaauac aucuucaaac      300

ccucaugcgu cccccucaug cgcugcggcg gcugcugcaa cgacgaagga cucgaaugcg      360

uacccaccga agaaucaaac aucacaaugc aaaucaugcg caucaaaccc caccaaggcc      420

aacacaucgg cgaaaugucc uuccuccaac acaacaaaug cgaaugccgc cccaaaaaag      480

accgagcacg acaagaaaaa aaauccgucc gaggcaaagg caaaggccaa aaacgaaaaa      540

gaaaaaaauc ccgcuacaaa uccugguccg uauacgucgg cgcccgaugc ugccucaugc      600

cauggucccu ccccggcccc cacccaugcg gccccugcuc cgaacgccgc aaacaccucu      660

ucguccaaga cccccaaacc ugcaaaugcu ccugcaaaaa caccgacucc agaugcaaag      720

cccgccaacu cgaacucaac gaacgcaccu gucgcugcga caaaccccga cgcuaaggac      780

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      840

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      900

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      960

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa agaauu                                          1046


<210>  5943
<211>  971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt11)

<400>  5943
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccccccucc uccgccgccu ccuccucgca gcccuacucc      120

aacuagcccc cgcacaagcc cccgucuccc aacccgacgc ccccggccac caacgcaaag      180

uagucuccug gauagacguc uacacccgcg ccaccuguca accccgcgaa gucguagucc      240

cccucacagu cgaacucaug ggcacagucg ccaaacaacu cguacccuca ugcgucaccg      300

uccaaagaug cggcggcugc ugccccgacg acggccucga augcgucccc accggccaac      360

accaaguccg caugcaaaua cucaugaucc gauacccauc aucccaacua ggagaaaugu      420

cacucgaaga acacucucaa ugcgaaugca gacccaaaaa aaaagacuca gccguaaaac      480

cagaccgcgc cgcaacaccc caccaccgcc cccaaccacg aucagucccc ggcugggacu      540

ccgcccccgg cgcccccucc cccgccgaca ucacccaccc cacccccgcc cccggcccau      600

ccgcccacgc cgcccccucc accaccucug cccuaacccc cggccccgcc gccgccgccg      660

cagacgccgc cgccucaucc gucgccaaag gcggcgccua aggacuagug caucacauuu      720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc      780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu      840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau      900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaagaau u                                                           971


<210>  5944
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt11)

<400>  5944
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgccggca cccguugccu ccuugcccuc cuccuacccc      120

aaguccuacu aggcggagca gccggccucg uccccgaacu cggccgccgc aaauucgccg      180

ccgccucauc cggacgcccc uccucacaac ccagcgacga aguacucuca gaauuugaac      240

uucgucuacu cuccauguuc ggccucaaac aacgacccac ucccucccgc gacgcagucg      300

uccccccuua caugcuagac cuuuaccgcc gccacuccgg ccaacccgga ucacccgccc      360

ccgaccaucg ccucgaaaga gccgccuccc gagccaauac cguccgcuca uuccaccacg      420

aagaaucacu cgaagaacua cccgaaacca gcggaaaaac aacacgcaga uucuucuuca      480

accucuccag cauccccacc gaagaauuua ucaccuccgc cgaacuacaa guauucagag      540

aacaaaugca ggacgcccuc ggcaacaacu ccagcuucca ccaccgcauc aacauauacg      600

aaauaaucaa acccgccaca gcuaacucca aguuccccgu cacacgccua cucgacaccc      660

gccuagucaa ccaaaaugcc ucccgcuggg aauccuucga cgucaccccc gccgucaugc      720

gauggaccgc acaaggccac gccaaucacg gcuucgucgu agaaguugca caccuagaag      780

aaaaacaagg cgucuccaaa cgccacgucc gcaucuccag aucccuacac caagacgaac      840

acucaugguc ccaaauccgc ccccuccuag ucaccuucgg acaugacggc aaaggacacc      900

cgcuccacaa acgcgaaaaa cgccaagcca aacacaaaca acgcaaacgc cucaaaucau      960

ccugcaaacg ccacccacuc uacguagacu ucuccgacgu aggauggaac gacuggauag     1020

ucgcaccccc aggcuaccac gcauucuacu gccacggaga augcccauuc ccacuugccg     1080

accaccucaa cuccaccaac cacgcuaucg uacaaacacu cgucaacucc gucaacucaa     1140

aaaucccaaa agcaugcugc guccccacag aacucucagc caucuccaug cucuaccucg     1200

acgaaaacga aaaggucguc cuaaaaaacu accaagacau ggucgucgaa ggcugcggcu     1260

gccgcuaggg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  5945
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt11)

<400>  5945
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacguccgau cacuacgcgc cgcagcccca cacuccuucg      120

uagcacucug ggcaccccua uucuuacucc gcuccgcacu agccgacuuc ucccucgaca      180

acgaagucca cucgagcuuc auccaccgcc gccuacgguc ccaagaaaga cgcgaaaugc      240

aacgcgaaau ccucucaauu cuaggacucc cccaccgccc ccgcccccac cuccaaggca      300

aacacaacuc ugcccccaug uucaugcucg accucuacaa cgccauggca guagaagaag      360

gaggcggacc cggcggccaa ggcuucucau accccuacaa agccguuuuc ucaacccaag      420

gcccgccccu cgcaucccuc caagacucac acuuccuaac cgacgccgac augguaaugu      480

cauucgucaa ccucguagaa caugacaaag aauuuuucca cccccgcuau caccaccgcg      540

aauuucgauu cgaccucucg aaaauacccg aaggcgaagc cgugaccgca gccgaauuuc      600

gcauauacaa agacuacauc cgcgaacgcu ucgacaacga aacauuccgc aucuccgucu      660

accaagugcu ccaagaacac cucggccgcg aaagcgaccu cuuccuacuu gacucccgca      720

cacuuugggc cucugaagaa gguuggcucg uauucgacau aacagccacc ucaaaccacu      780

ggguagucaa cccccgucac aaccuaggac uccagcuauc aguagaaaca cucgacggcc      840

agagcaucaa ccccaaacuu gcgggacuca ucggccgcca cggaccacaa aacaagcagc      900

ccuucauggu cgccuucuuu aaagccaccg aaguacauuu cagauccaua cgcuccaccg      960

gguccaaaca acgaucacaa aaccgaucca aaaccccaaa aaaccaagaa gcucuacgaa     1020

uggcaaacgu agcugaaaac agcuccucag accaacgcca agccugcaaa aaacacgaac     1080

ucuacgucuc cuuccgagac cucggcuggc aagacuggau caucgcccca gaaggcuacg     1140

cagcauacua cugcgaaggc gaaugcgccu ucccccuuaa cucuuacaug aacgccacca     1200

accacgcaau cguccagacc cucguacacu ucaucaaccc cgaaacuguc cccaaacccu     1260

gcugcgcccc cacccaauua aacgcaaucu ccguccucua cuucgacgac uccucgaacg     1320

ucauacucaa aaaauaccga aacauggucg uccgcgccug cggcugccau uaaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  5946
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt11)

<400>  5946
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagccuccg ccgcccuccu cugccuccuc cucaccgccg      120

ccgccuucuc cccccaaggc cuagcccaac ccgucggcau caacaccucc accaccuguu      180

gcuaccgauu caucaacaaa aaaaucccca aacaacgccu cgaauccuac cgccgcacca      240

ccuccucaca cugcccccgc gaagccguca ucuucaaaac caaacucgac aaagaaaucu      300

gcgccgaccc cacccaaaaa uggguccaag acuucaugaa acaccucgac aaaaaaaccc      360

aaacccccaa acucuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  5947
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt11)

<400>  5947
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uccucaccug gauccucccc acccuccucu      120

accgcuccug cuuccacauc aucugccucg ucggcaccau cucccucgcc ugcaacgaca      180

ugacccccga acaaauggcc acaaacguca acugcuccuc ccccgaacgc cacacccgcu      240

ccuacgacua cauggaaggc ggcgacaucc gcguccgccg acucuucugc cgcacccaau      300

gguaccuacg caucgacaaa cgcggcaaag uaaaaggcac ccaagaaaug aaaaacaacu      360

acaacaucau ggaaauccgc acagucgccg ucggcauagu cgcaaucaaa ggcgucgaau      420

ccgaauuuua ccucgccaug aacaaagaag gcaaacucua cgccaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa cucauccucg aaaaccacua caacaccuac gccuccgcca      540

aauggaccca caacggcggc gaaauguucg ucgcccucaa ccaaaaaggc auccccgucc      600

gcggcaaaaa aaccaaaaaa gaacaaaaaa ccgcccacuu ccuccccaug gccaucaccu      660

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  5948
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt11)

<400>  5948
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcccccc gcgaacuagc cguaggcauc gaccucggca      120

caaccuacag cugugucggc guauuccaac aaggcagagu agaaauccua gccaacgacc      180

aaggcaacag aacgacccca ucauacgucg cguucaccga cacagaaagg cuaguaggag      240

acgcagcaaa aucccaagca gcccuaaacc cgcacaacac uguauucgac gccaaacgcc      300

uaaucggacg aaaauucgca gacacaaccg uccaaucaga caugaaacac uggccauucc      360

aagucgucuc cgaaggugga aaacccaaag uacgaguaug cuaccgaggg gaagacaaaa      420

cauucuaccc agaagaaaua agcucaaugg uacuaagcaa aaugaaagaa accgcggaag      480

ccuaccuagg ccaaccagua aaacacgccg uaaucacggu cccgaccuac uucagcaacu      540

cccagagaca ggccaccaaa gacgcaggag caaucgcagg ccuaaaagua cucccaauca      600

uaaacgaagc cacagccgca gcaauagccu acggccugga ccgaagagga gccggcaaac      660

gaaacguacu cauauucgac cuaggaggag gaacauucga cguauccgua cucucgaucg      720

acgccggggu cuucgaagua aaagcuaccg ccggcgacac ccaccuagga ggcgaagacu      780

ucgacaaccg ccuagucaac cacuucaugg aagaauuucg cagaaaacac ggcaaagacc      840

uaagcggaaa caaacgagcc cucagacgac uccgaacagc cugcgaacga gccaaacgca      900

ccccaucaag cagcacccag gccacacuag aaaucgacuc ccuauucgaa ggcguagacu      960

ucuacaaaag caucaccaga gccagauucg aagaacucug cagcgaccua uuccgaagca     1020

cccuagaacc cguggaaaaa gcccuccgcg acgccaaacu agacaaagca caaauccacg     1080

acuucguacu aggcggcggg cuccacagcc acccacaagg cgcagaaguc gccgcaggcc     1140

uacuccaacg acaaggcgca gaacaagaac accagccaua aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  5949
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt11)

<400>  5949
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaagaag ugcaccacgg ggaagaggaa gucgaaaccu      120

ucgccuucca ggccgagaua gcccaacuca ugagcuuaau cauaaacacc uucuacucca      180

acaaagaaau cuuccucaga gaguugauau caaacgcaag cgacgcccug gacaagauaa      240

gauacgaaag ccuaacagac ccaucaaaac uggacucagg aaaggaguua aaaauagaca      300

ucaucccaaa cccacaagaa cgcacgcuca cccucgugga caccggaaua ggaaugacaa      360

aagccgaccu cauaaacaau cucggcacga uagccaagag cgggacaaaa gccuucaugg      420

aggcccuaca agcaggagcc gacauaagca ugaucggaca auucggcgua ggcuucuaca      480

gcgcauaccu cgucgccgaa aaggugguag uaaucacaaa acacaacgac gacgaacaau      540

acgccuggga aagcagcgcc ggcgggagcu ucacagucag agcagaccac ggcgaaccua      600

uaggacgcgg gacuaaagua auccuccacc uaaaggaaga ccaaaccgaa uacuuagaag      660

aacgcagggu caaggaaguc gucaaaaaac acagccaguu caucggcuac cccauaaccc      720

ucuaccugga aaaagagagg gaaaaggaaa uaagugacga cgaggccgag gaagaaaaag      780

gagaaaaaga agaagaagac aaagacgacg aagaaaagcc caagaucgaa gacguaggaa      840

gcgacgaaga agacgacuca ggaaaggaca agaaaaaaaa aacgaaaaaa aucaaagaga      900

aauacaucga ccaagaagaa cugaacaaaa caaaaccaau cuggaccagg aaccccgaug      960

acaucacaca agaagaauac ggggaauuuu acaaaucgcu aacaaacgac ugggaggacc     1020

accucgcggu aaagcacuuc agcguggaag gacaacucga auuuagagca cuacuauuca     1080

ucccaaggag agcgccauuc gaccuguucg aaaacaagaa aaaaaaaaac aacauaaagc     1140

uauacguccg acgagucuuc auaauggacu caugcgacga acugauccca gaauaccuaa     1200

acuucauccg gggcguagua gacuccgaag accucccacu caacaucagc cgagaaaugc     1260

uacaacagag caagauacug aaagugauca gaaaaaacau cguaaaaaag ugccuagaac     1320

uauucagcga auuagcagag gauaaagaaa acuacaagaa auucuacgaa gccuucagca     1380

agaaccuaaa acugggcaua cacgaagaca gcaccaaucg aaggcgccua agcgaacuac     1440

uaagauacca cacaagucag agcggcgacg agaugacgag ccuauccgaa uacguuagcc     1500

ggaugaaaga aacgcaaaag ucaauauacu acaucaccgg agagagcaag gaacaaguag     1560

cgaacucggc auucgucgaa cgcgugcgaa agcgcggauu cgaagucgua uacaugacgg     1620

agcccaucga cgaguacugu guacaacagc ucaaagaauu ugacggcaaa agccuagucu     1680

caguaaccaa agaaggacua gaauugcccg aagacgaaga agagaagaaa aaaauggaag     1740

aaucaaaagc caaauucgag aacuugugca agcugaugaa agagauccua gacaaaaagg     1800

uagaaaaggu cacgaucuca aaccggcugg ugagcucgcc cugcugcauc gucacgagca     1860

cauacggcug gacagcaaac auggaacgaa uaaugaaagc acaagcccuc agagacaacu     1920

caaccauggg guacaugaug gccaagaaac accucgaaau aaaccccgac cacccuauag     1980

uagaaacgcu caggcaaaag gccgaagcag acaaaaacga caaagccgua aaagaccucg     2040

ugguccugcu cuuugaaaca gcccuacucu caagcggauu uucacuggag gacccacaaa     2100

cccacagcaa cagaaucuac cgaaugauua agcucggacu ggguauugac gaggacgaag     2160

uagccgcgga agaacccaac gcggcagucc ccgacgaaau cccgccccug gaaggggacg     2220

aggacgcauc aagaauggaa gaggucgacu agggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  5950
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt11)

<400>  5950
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccaccuccgc cuucggcccc gucgccuucu      120

cccucggccu ccuacucgua cuccccgccg ccuucccagc ccccgucccc ccaggcgaag      180

acuccaaaga cgucgccgcc ccccaccgcc aaccucucac cucauccgaa cgcaucgaca      240

aacaaauacg cuacauccuc gacggcaucu ccgcccuccg caaagaaacc ugcaacaaau      300

caaacaugug cgaauccuca aaagaagccc ucgccgaaaa caaccuaaac cuccccaaaa      360

uggccgaaaa agacggcugc uuccaauccg gcuucaacga agaaacaugc cucgucaaaa      420

uaaucaccgg acuccucgaa uuugaagucu accucgaaua ccuacaaaac cgcuucgaau      480

cauccgaaga acaagcccgc gccguccaaa ugucaaccaa aguccucauc caauuccucc      540

aaaaaaaagc caaaaaccuc gacgccauca caacccccga ccccaccacc aacgccuccc      600

uacucaccaa acuccaagcc caaaaccaau ggcuccaaga caugaccacc caccucaucc      660

uccgcuccuu caaagaauuu cuccaauccu cccuccgcgc ccuccgacaa auguagggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  5951
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt11)

<400>  5951
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg uacucgcagc cuuccuauuc cuauccugga      120

cccacugccg cgcauuaccc cuccccucag gaggcgauga agacgaccuu uccgaagaag      180

accugcaauu cgccgaacgc uaccuccgau ccuacuacca ccccaccaac cucgccggca      240

uacucaaaga aaacgcagcc ucauccauga cagaacgccu ccgcgaaaug caauccuucu      300

uuggccucga agucaccgga aaacuugacg acaacacgcu agacgucaug aaaaaaccca      360

gaugcggagu ccccgacguc ggcgaauaca acgucuuccc cagaacccua aaauggucaa      420

aaaugaaccu caccuacaga auagucaacu acaccccuga caugacccac uccgaaguag      480

aaaaagccuu caaaaaagcc uucaaagucu ggucugacgu uaccccccuc aacuucaccc      540

gacuccacga cggcaucgcc gacauaauga ucuccuucgg aaucaaagaa cacggcgacu      600

ucuaccccuu cgacggacca ucaggccuac ucgcccacgc cuucccacca ggacccaacu      660

acggaggcga cgcccacuuc gaugacgacg aaaccuggac cuccuccucc aaaggcuaca      720

accucuuccu aguagccgca cacgaauuug gccacucacu aggacuagac cacuccaaag      780

accccggcgc ucuuauguuc cccaucuaca ccuacacugg gaaaucccac uucaugcucc      840

ccgacgacga cguacaaggc auccaaagcc ucuacggccc gggcgacgaa gaucccaacc      900

ccaaacaccc caaaacacca gacaaaugcg accccucacu aucacuagac gcaaucaccu      960

cccuccgugg cgaaacuaug aucuucaaag accgauucuu cuggcgcuua cacccccaac     1020

aagucgacgc cgaacucuuc cuuaccaaau cauucuggcc cgaacucccc aaccgcaucg     1080

acgccgccua cgaacacccc agccaugacc ucaucuuuau cuuccgcggg agaaaauucu     1140

gggcacuaaa cggauacgac auacucgaag gcuacccaaa aaaaaucucc gaacuaggcc     1200

ucccaaagga agucaaaaag aucuccgcag caguacacuu cgaagacacc ggcaaaaccc     1260

uccuauucuc agguaaccaa guauggcgcu acgacgacac caaccacauc auggacaaag     1320

acuacccccg ccucaucgaa gaagacuucc ccggcauagg cgacaaaguc gacgccgucu     1380

augaaaaaaa cggcuacaua uacuucuuua acggccccau ccaauuugaa uacuccauau     1440

gguccaaccg caucguacgc guuaugccag ccaacuccau ccucuggugc uaaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  5952
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt11)

<400>  5952
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgccuaa ucuucgucua cacccuaauc ugcgccaacu      120

ucugcuccug ccgagacacc uccgccaccc cacaauccgc cuccauaaaa gcacuccgga      180

augccaacuu acgccgggac gaccuauacc gucgagacga aacaauccaa guaaaaggaa      240

acggcuacgu gcaaucgccc cgauucccaa acuccuaccc acgcaaccuc cuccucaccu      300

ggcgacuaca cucccaagaa aacacucgca uccaacucgu cuucgacaac caguucggcc      360

uggaagaagc cgaaaacgac aucugccgcu acgacuucgu cgaagucgaa gacauaucag      420

aaaccuccac caucauacgc ggccgcuggu gcggccacaa agagguaccc ccccgcauca      480

aaucccgcac aaaccaaauc aaaauaaccu ucaaaucaga cgacuacuuc guagcuaaac      540

ccggauucaa aaucuacuac ucccuccuag aagacuucca acccgccgca gcauccgaga      600

ccaacuggga auccguaacc uccuccauau ccggcguauc cuacaacagc cccuccguca      660

cagaccccac ccuuauagcc gacgcccucg acaaaaaaau cgccgaauuu gacaccgucg      720

aagaucuccu aaaauacuuc aaccccgaau cauggcaaga agaccucgaa aacauguacc      780

uagacacccc acgauaccgc ggacgcucau accacgaccg aaaauccaaa gucgaccucg      840

accgacucaa cgacgacgcc aaacgcuaca gcugcacacc acgcaacuac uccgucaaca      900

uccgcgaaga acuaaaacuc gccaacguag ucuucuuccc ccgcugccuu cucguccaaa      960

gaugcggcgg caacugcggc uguggaaccg uaaacuggcg cagcugcacc uguaacucag     1020

gcaaaaccgu caaaaaauac cacgaagucc uccaauucga accaggccac aucaaacgcc     1080

gcggccgagc caaaacaaug gcccucgucg acauccagcu cgaccaccac gaacgcugcg     1140

acugcauaug cuccagccgc cccccucgcu aaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  5953
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt11)

<400>  5953
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccacu ccaaauuccc ugccgcaggc augucccgac      120

cccucgacac cucccuccga cucaaaaccu ucuccucaaa guccgaauac caacucgucg      180

ucaacgccgu ccguaaacuc caagaauccg gcuucuacug guccgccguc accgguggug      240

aagcaaaccu ccuccucucc gcagaacccg ccggcaccuu ccucauccgc gacuccucag      300

accaacgcca cuucuucacc cucucaguca aaacccaauc cggcaccaaa aaccuccgca      360

uccaaugcga aggcggcucc uucucccucc aauccgaccc acgcuccaca caaccugucc      420

cacgcuucga cugcguccuc aaacucgucc accacuacau gccacccccc ggcgcccccu      480

ccuucccauc cccccccacc gaacccuccu cagaaguccc cgaacaaccc ucagcccaac      540

cccuccccgg cucccccccc cgccgcgcau acuacaucua cuccggcggc gaaaaaaucc      600

cacucguacu cucccgcccc cucuccucca acgucgccac ccuacaacac cucugccgca      660

aaaccgucaa cggccaccuc gacuccuacg aaaaagucac ccaacuaccc ggccccaucc      720

gcgaauuucu cgaccaauac gaugcacccc uauaaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  5954
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt11)

<400>  5954
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guccccuccg ccggccaacu cgcccuauuc gcccucggaa      120

ucguccucgc agccugccaa gcccucgaaa acuccaccuc cccccucucc gccgaccccc      180

ccgucgccgc cgccgucguc ucccacuuca acgacugccc cgacucccac acccaauucu      240

gcuuccacgg caccugucgc uuccucgucc aagaagacaa acccgccugc gucugccacu      300

ccggcuacgu cggcgcccgc ugcgaacacg ccgaccuccu cgccgucguc gccgccuccc      360

aaaaaaaaca agccaucacc gcccucgucg ucgucuccau cgucgcccuc gccguccuca      420

ucaucaccug uguccuaauc cacugcugcc aaguccgcaa acacugcgaa uggugccgcg      480

cccucaucug ccgccacgaa aaacccuccg cccuccucaa aggccgcacc gccugcugcc      540

acuccgaaac agucguuuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  5955
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt11)

<400>  5955
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uccucuccgc cuuccucaua uuacaccucg      120

ucaccguugc ccuaucccuc ucgacuugcu ccacccucga cauggaccaa uucaugcgca      180

aaagaaucga agcaauccga ggccaaaucc ucucaaaacu caaacuuaca ucccccccug      240

aagacuaucc agaacccgag gaaguccccc cugaagucau auccauauac aacagcaccc      300

gcgaccuacu ccaagaaaaa gccucgcgac gagccgcagc cugcgaacgc gaacgcagcg      360

acgaagaaua cuacgccaag gaagucuaca aaaucgacau gccgcccuuc uucccaucag      420

agaaugcuau cccccccacc uucuaccgac cauacuuccg caucguccgc uucgacgucu      480

ccgcaaugga aaaaaacgcc uccaaccucg ucaaagccga auuucgcguc uuccgccugc      540

aaaaccccaa agcccgcguu cccgaacaac gcaucgaacu cuaccaaaua cucaaaucca      600

aagaccucac cucucccacc caacguuaca ucgacucuaa aguagucaaa acacgcgccg      660

aaggcgaaug gcucuccuuc gacguaaccg acgccguaca cgaauggcuc caccacaaag      720

acagaaaccu cggauucaaa aucucccuac acugccccug cugcacuuuc guccccucca      780

acaacuacau aauucccaac aaauccgaag aacuugaagc ccgcuucgcc ggcaucgacg      840

gaaccucgac cuacacuuca ggcgaccaga aaaccauuaa auccacccgc aaaaaaaacu      900

cgggcaaaac accccaccuc cuacucaugc uccucccauc cuaccggcua gaaucccaac      960

aaaccaaccg acgcaaaaaa cgagcccucg acgcagccua cugcuuccgu aacguccaag     1020

acaauugcug ccuacgccca cucuacaucg auuucaaacg ugaccucgga uggaaaugga     1080

uccaugaacc caaaggcuac aacgccaacu ucugcgcagg cgcaugcccc uaccucugga     1140

gcuccgacac ccaacacucc cgcguccuaa gccuuuacaa caccaucaac cccgaagccu     1200

cagccucccc cugcugcguc ucccaagacc ucgaaccacu aacaauccuc uacuacaucg     1260

gcaaaacccc caaaauagaa caacucucca acaugaucgu caaauccugc aaaugcuccu     1320

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  5956
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt11)

<400>  5956
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaccagucg cagucugggc cgcccucgcc guaggccuug      120

aacucugggc agccgcccac gcccucccag cacaagucgc auucacuccc uacgcacccg      180

aacccggcuc caccugucgc cuacgcgaau acuaugacca aacagcacaa augugcugcu      240

ccaaaugcuc ucccggccaa cacgcuaaag uauucugcac aaaaaccucu gacaccguau      300

gcgacucaug cgaagacucc acauauaccc aacucuggaa cugggucccc gaaugccucu      360

ccugcggcuc ccgcugcagc ucagaccaag uagaaaccca agcaugcacc cgcgagcaaa      420

accgcaucug cacaugccgc cccggcuggu acugcgcucu cuccaaacaa gaaggcugca      480

gacuuugugc accucugagg aaaugccgac caggcuuugg uguagcaaga cccgguaccg      540

aaaccucaga cgucgucugc aaaccgugug cacccggcac cuucucaaac accaccuccu      600

cuaccgacau cugccgacca caucaaaucu gcaacguagu cgccauccca ggcaacgccu      660

ccauggacgc cguaugcacc ucgaccuccc ccacccgcuc cauggccccc ggcgccguac      720

accuacccca acccgucucc acccgauccc agcacaccca acccacccca gaacccagca      780

ccgccccguc aaccucauuc cuacucccaa ugggccccuc cccacccgca gaaggcucca      840

caggcgauuu cgcccucccc guaggacuaa uaguuggcgu caccgcccua ggccuccuua      900

ucaucggcgu agucaacugc gucaucauga cccaagucaa aaaaaaaccc cucugccucc      960

aacgcgaagc caaaguccca caccucccag ccgacaaagc ccgcggaacc caaggccccg     1020

aacaacaaca ccuccucauc accgcccccu caucaagcuc cuccucacuc gaaucauccg     1080

ccuccgcccu cgaucgacgc gcccccacac gcaaccaacc acaagcccca ggcguagaag     1140

cguccggcgc cggcgaagcc cgcgccucca ccggcucguc cgacuccuca ccaggagguc     1200

acggcaccca aguaaauguc accuguaucg ugaacguuug uuccuccuca gaucacagcu     1260

cccaauguuc uucccaagcc uccuccacaa ugggcgacac cgauuccagc cccucagaau     1320

cccccaaaga cgaacaaguc ccauucucaa aagaagagug ugccuuccga ucccagcucg     1380

aaacaccaga aacccuacuc gguucaaccg aagaaaaacc ccucccccuc ggcgucccag     1440

acgcaggcau gaaacccucc uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  5957
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt11)

<400>  5957
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc uaagcugggu ccacuggucc cucgcccuac      120

uccucuaccu acaccacgcc aaaugguccc aagccgcacc cauggccgaa ggcggcggcc      180

aaaaccacca cgaagucguc aaauucaugg acgucuacca acgcucauac ugccacccca      240

ucgaaacccu cgucgacauc uuccaagaau accccgacga aauagaauac aucuucaaac      300

ccucaugcgu cccccucaug cgcugcggcg gcugcugcaa cgacgaagga cucgaaugcg      360

uacccaccga agaaucaaac aucacaaugc aaaucaugcg caucaaaccc caccaaggcc      420

aacacaucgg cgaaaugucc uuccuccaac acaacaaaug cgaaugccgc cccaaaaaag      480

accgagcacg acaagaaaaa aaauccgucc gaggcaaagg caaaggccaa aaacgaaaaa      540

gaaaaaaauc ccgcuacaaa uccugguccg uauacgucgg cgcccgaugc ugccucaugc      600

cauggucccu ccccggcccc cacccaugcg gccccugcuc cgaacgccgc aaacaccucu      660

ucguccaaga cccccaaacc ugcaaaugcu ccugcaaaaa caccgacucc agaugcaaag      720

cccgccaacu cgaacucaac gaacgcaccu gucgcugcga caaaccccga cgcuaaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  5958
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt11)

<400>  5958
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccccccucc uccgccgccu ccuccucgca gcccuacucc      120

aacuagcccc cgcacaagcc cccgucuccc aacccgacgc ccccggccac caacgcaaag      180

uagucuccug gauagacguc uacacccgcg ccaccuguca accccgcgaa gucguagucc      240

cccucacagu cgaacucaug ggcacagucg ccaaacaacu cguacccuca ugcgucaccg      300

uccaaagaug cggcggcugc ugccccgacg acggccucga augcgucccc accggccaac      360

accaaguccg caugcaaaua cucaugaucc gauacccauc aucccaacua ggagaaaugu      420

cacucgaaga acacucucaa ugcgaaugca gacccaaaaa aaaagacuca gccguaaaac      480

cagaccgcgc cgcaacaccc caccaccgcc cccaaccacg aucagucccc ggcugggacu      540

ccgcccccgg cgcccccucc cccgccgaca ucacccaccc cacccccgcc cccggcccau      600

ccgcccacgc cgcccccucc accaccucug cccuaacccc cggccccgcc gccgccgccg      660

cagacgccgc cgccucaucc gucgccaaag gcggcgccua aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  5959
<211>  534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__P45561-2__SsAMELX-001-2

<400>  5959
auggggaccu ggauuuuguu ugcuugccuc cugggagcag ccuucucuau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaua uaagacaucc guacacuucc      120

uauggguacg aacccauggg uggauggcug caccaccaaa ucauacccgu ggugucgcag      180

cagacucccc agagucaugc ccuucagccu caucaccaca uccccauggu gccagcucaa      240

cagcccggga ucccccagca gccaaugaug ccacuuccug gccaacacuc caugacucca      300

acccaacacc accagccaaa ccucccucug cccgcccagc agcccuucca gccccagccc      360

guccagcccc agccucacca gccccugcag ccccagucac ccaugcaccc cauccagccc      420

uugcugccac agccaccucu gccuccgaug uucuccaugc agucucugcu uccugaccug      480

ccucuggaag cauggccagc aacagacaag accaagcggg aggaagugga uuaa            534


<210>  5960
<211>  570
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__NP_998965.1__SsAMELX-001-3

<400>  5960
auggggaccu ggauuuucuu ugccugccuu uugggagcau cccuugcuau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggugcuuac cccucugaag      120

ugguaccaga acaugauaag acauccguac acuuccuaug gguacgaacc caugggugga      180

uggcugcacc accaaaucau acccguggug ucgcagcaga cuccccagag ucaugcccuu      240

cagccucauc accacauccc cauggugcca gcucaacagc ccgggauccc ccagcagcca      300

augaugccac uuccuggcca acacuccaug acuccaaccc aacaccacca gccaaaccuc      360

ccucugcccg cccagcagcc cuuccagccc cagcccgucc agccccagcc ucaccagccc      420

cugcagcccc agucacccau gcaccccauc cagcccuugc ugccacagcc accucugccu      480

ccgauguucu ccaugcaguc ucugcuuccu gaccugccuc uggaagcaug gccagcaaca      540

gacaagacca agcgggagga aguggauuaa                                       570


<210>  5961
<211>  219
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__K7GPB2__SsAMELX-002

<400>  5961
auggggaccu ggauuuuguu ugcuugccuc cugggagcag ccuucucuau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggugcuuac cccucugaag      120

ugguaccaga acaugauaag acauccgucu cugcuuccug accugccucu ggaagcaugg      180

ccagcaacag acaagaccaa gcgggaggaa guggauuaa                             219


<210>  5962
<211>  612
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__K7GLD0__SsAMELX-003

<400>  5962
auggggaccu ggauuuuguu ugcuugccuc cugggagcag ccuucucuau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggacuuaua cuuggaggcu      120

auccguauug acaggacugc auucgugcuu accccucuga agugguacca gaacaugaua      180

agacauccgu acacuuccua ugguuacgaa cccaugggug gauggcugca ccaccaaauc      240

auucccgugg ugucgcagca gacuccccag agucaugccc uucagccuca ucaccacauc      300

cccauggugc cagcucaaca gcccgggauc ccccagcagc caaugaugcc acuuccuggc      360

caacacucca ugacuccaac ccaacaccac cagccaaacc ucccucugcc cgcccagcag      420

cccuuccagc cccagcccgu ccagccccag ccucaccagc cccugcagcc ccagucaccc      480

augcacccca uccagcccuu gcugccacag ccaccucugc cuccgauguu cuccaugcag      540

ucucugcuuc cugaccugcc ucuggaagca uggccagcaa cagacaagac caagcgggag      600

gaaguggauu aa                                                          612


<210>  5963
<211>  498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__K7GPE9__SsAMELX-004

<400>  5963
auggggaccu ggauuuuguu ugcuugccuc cugggagcag ccuucucuau gccucuacca       60

ccucauccug ggcacccugg uuauaucaac uucagcuaug aggugcuuac cccucugaag      120

ugguaccaga acaugauaag acauccgacu ccccagaguc augcccuuca gccucaucac      180

cacaucccca uggugccagc ucaacagccc gggauccccc agcagccaau gaugccacuu      240

ccuggccaac acuccaugac uccaacccaa caccaccagc caaaccuccc ucugcccgcc      300

cagcagcccu uccagcccca gcccguccag ccccagccuc accagccccu gcagccccag      360

ucacccaugc accccaucca gcccuugcug ccacagccac cucugccucc gauguucucc      420

augcagucuc ugcuuccuga ccugccucug gaagcauggc cagcaacaga caagaccaag      480

cgggaggaag uggauuaa                                                    498


<210>  5964
<211>  522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Sus 
       scrofa__J9JIM4__SsAMELX-201

<400>  5964
augccucuac caccucaucc ugggcacccu gguuauauca acuucagcua ugaggugcuu       60

accccucuga agugguacca gaacaugaua agacauccgu acacuuccua uggguacgaa      120

cccaugggug gauggcugca ccaccaaauc auacccgugg ugucgcagca gacuccccag      180

agucaugccc uucagccuca ucaccacauc cccauggugc cagcucaaca gcccgggauc      240

ccccagcagc caaugaugcc acuuccuggc caacacucca ugacuccaac ccaacaccac      300

cagccaaacc ucccucugcc cgcccagcag cccuuccagc cccagcccgu ccagccccag      360

ccucaccagc cccugcagcc ccagucaccc augcacccca uccagcccuu gcugccacag      420

ccaccucugc cuccgauguu cuccaugcag ucucugcuuc cugaccugcc ucuggaagca      480

uggccagcaa cagacaagac caagcgggag gaaguggauu aa                         522


<210>  5965
<211>  2961
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_006120.1__HsBMP1

<400>  5965
augcccggcg uggcccgccu gccgcugcug cucgggcugc ugcugcuccc gcgucccggc       60

cggccgcugg acuuggccga cuacaccuau gaccuggcgg aggaggacga cucggagccc      120

cucaacuaca aagaccccug caaggcggcu gccuuucuug gggacauugc ccuggacgaa      180

gaggaccuga gggccuucca gguacagcag gcuguggauc ucagacggca cacagcucgu      240

aaguccucca ucaaagcugc aguuccagga aacacuucua cccccagcug ccagagcacc      300

aacgggcagc cucagagggg agccuguggg agauggagag guagaucccg uagccggcgg      360

gcggcgacgu cccgaccaga gcgugugugg cccgaugggg ucauccccuu ugucauuggg      420

ggaaacuuca cugguagcca gagggcaguc uuccggcagg ccaugaggca cugggagaag      480

cacaccugug ucaccuuccu ggagcgcacu gacgaggaca gcuauauugu guucaccuau      540

cgaccuugcg ggugcugcuc cuacgugggu cgccgcggcg ggggccccca ggccaucucc      600

aucggcaaga acugugacaa guucggcauu gugguccacg agcugggcca cgucgucggc      660

uucuggcacg aacacacucg gccagaccgg gaccgccacg uuuccaucgu ucgugagaac      720

auccagccag ggcaggagua uaacuuccug aagauggagc cucaggaggu ggagucccug      780

ggggagaccu augacuucga cagcaucaug cauuacgcuc ggaacacauu cuccaggggc      840

aucuuccugg auaccauugu ccccaaguau gaggugaacg gggugaaacc ucccauuggc      900

caaaggacac ggcucagcaa gggggacauu gcccaagccc gcaagcugua caagugccca      960

gccuguggag agacccugca agacagcaca ggcaacuucu ccuccccuga auaccccaau     1020

ggcuacucug cucacaugca cugcgugugg cgcaucucug ucacacccgg ggagaagauc     1080

auccugaacu ucacgucccu ggaccuguac cgcagccgcc ugugcuggua cgacuaugug     1140

gagguccgag auggcuucug gaggaaggcg ccccuccgag gccgcuucug cggguccaaa     1200

cucccugagc cuaucgucuc cacugacagc cgccucuggg uugaguuccg cagcagcagc     1260

aauuggguug gaaagggcuu cuuugcaguc uacgaagcca ucugcggggg ugaugugaaa     1320

aaggacuaug gccacauuca aucgcccaac uacccagacg auuaccggcc cagcaaaguc     1380

ugcaucuggc ggauccaggu gucugagggc uuccacgugg gccucacauu ccaguccuuu     1440

gagauugagc gccacgacag cugugccuac gacuaucugg aggugcgcga cgggcacagu     1500

gagagcagca cccucaucgg gcgcuacugu ggcuaugaga agccugauga caucaagagc     1560

acguccagcc gccucuggcu caaguucguc ucugacgggu ccauuaacaa agcgggcuuu     1620

gccgucaacu uuuucaaaga gguggacgag ugcucucggc ccaaccgcgg gggcugugag     1680

cagcggugcc ucaacacccu gggcagcuac aagugcagcu gugaccccgg guacgagcug     1740

gccccagaca agcgccgcug ugaggcugcu uguggcggau uccucaccaa gcucaacggc     1800

uccaucacca gcccgggcug gcccaaggag uaccccccca acaagaacug caucuggcag     1860

cugguggccc ccacccagua ccgcaucucc cugcaguuug acuucuuuga gacagagggc     1920

aaugaugugu gcaaguacga cuucguggag gugcgcagug gacucacagc ugacuccaag     1980

cugcauggca aguucugugg uucugagaag cccgagguca ucaccuccca guacaacaac     2040

augcgcgugg aguucaaguc cgacaacacc guguccaaaa agggcuucaa ggcccacuuc     2100

uucucagaca aggacgagug cuccaaggau aacggcggcu gccagcagga cugcgucaac     2160

acguucggca guuaugagug ccaaugccgc aguggcuucg uccuccauga caacaagcac     2220

gacugcaaag aagccggcug ugaccacaag gugacaucca ccagugguac caucaccagc     2280

cccaacuggc cugacaagua ucccagcaag aaggagugca cgugggccau cuccagcacc     2340

cccgggcacc gggucaagcu gaccuucaug gagauggaca ucgaguccca gccugagugu     2400

gccuacgacc accuagaggu guucgacggg cgagacgcca aggcccccgu ccucggccgc     2460

uucuguggga gcaagaagcc cgagcccguc cuggccacag gcagccgcau guuccugcgc     2520

uucuacucag auaacucggu ccagcgaaag ggcuuccagg ccucccacgc cacagagugc     2580

gggggccagg uacgggcaga cgugaagacc aaggaccuuu acucccacgc ccaguuuggc     2640

gacaacaacu acccuggggg uguggacugu gaguggguca uuguggccga ggaaggcuac     2700

ggcguggagc ucguguucca gaccuuugag guggaggagg agaccgacug cggcuaugac     2760

uacauggagc uguucgacgg cuacgacagc acagccccca ggcuggggcg cuacuguggc     2820

ucagggccuc cugaggaggu guacucggcg ggagauucug uccuggugaa guuccacucg     2880

gaugacacca ucaccaaaaa agguuuccac cuccgauaca ccagcaccaa guuccaggac     2940

acacuccaca gcaggaagug a                                               2961


<210>  5966
<211>  1191
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001191.1__HsBMP2

<400>  5966
augguggccg ggacccgcug ucuucuagcg uugcugcuuc cccagguccu ccugggcggc       60

gcggcuggcc ucguuccgga gcugggccgc aggaaguucg cggcggcguc gucgggccgc      120

cccucauccc agcccucuga cgagguccug agcgaguucg aguugcggcu gcucagcaug      180

uucggccuga aacagagacc cacccccagc agggacgccg uggugccccc cuacaugcua      240

gaccuguauc gcaggcacuc aggucagccg ggcucacccg ccccagacca ccgguuggag      300

agggcagcca gccgagccaa cacugugcgc agcuuccacc augaagaauc uuuggaagaa      360

cuaccagaaa cgagugggaa aacaacccgg agauucuucu uuaauuuaag uucuaucccc      420

acggaggagu uuaucaccuc agcagagcuu cagguuuucc gagaacagau gcaagaugcu      480

uuaggaaaca auagcaguuu ccaucaccga auuaauauuu augaaaucau aaaaccugca      540

acagccaacu cgaaauuccc cgugaccaga cuuuuggaca ccagguuggu gaaucagaau      600

gcaagcagau gggaaaguuu ugaugucacc cccgcuguga ugcgguggac ugcacaggga      660

cacgccaacc auggauucgu gguggaagug gcccacuugg aggagaaaca aggugucucc      720

aagagacaug uuaggauaag caggucuuug caccaagaug aacacagcug gucacagaua      780

aggccauugc uaguaacuuu uggccaugau ggaaaagggc auccucucca caaaagagaa      840

aaacgucaag ccaaacacaa acagcggaaa cgccuuaagu ccagcuguaa gagacacccu      900

uuguacgugg acuucaguga cguggggugg aaugacugga uuguggcucc cccgggguau      960

cacgccuuuu acugccacgg agaaugcccu uuuccucugg cugaucaucu gaacuccacu     1020

aaucaugcca uuguucagac guuggucaac ucuguuaacu cuaagauucc uaaggcaugc     1080

ugugucccga cagaacucag ugcuaucucg augcuguacc uugacgagaa ugaaaagguu     1140

guauuaaaga acuaucagga caugguugug gaggguugug ggugucgcua g              1191


<210>  5967
<211>  1227
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001193.2__HsBMP4

<400>  5967
augauuccug guaaccgaau gcugaugguc guuuuauuau gccaaguccu gcuaggaggc       60

gcgagccaug cuaguuugau accugagacg gggaagaaaa aagucgccga gauucagggc      120

cacgcgggag gacgccgcuc agggcagagc caugagcucc ugcgggacuu cgaggcgaca      180

cuucugcaga uguuugggcu gcgccgccgc ccgcagccua gcaagagugc cgucauuccg      240

gacuacaugc gggaucuuua ccggcuucag ucuggggagg aggaggaaga acagauccac      300

agcacugguc uugaguaucc ugagcgcccg gccagccggg ccaacaccgu gaggagcuuc      360

caccacgaag aacaucugga gaacauccca gggaccagug aaaacucugc uuuucguuuc      420

cucuuuaacc ucagcagcau cccugagaac gaggugaucu ccucugcaga gcuucggcug      480

uuccgggagc aggucgacca gggcccugau ugggaaaggg gcuuccaccg uauaaacauu      540

uaugagguua ugaagccccc agcagaagug gugccugggc accucaucac acgacuacug      600

gacacgagac ugguccacca caaugugaca cggugggaaa cuuuugaugu gagcccugcg      660

guccuucgcu ggacccggga gaagcagcca aacuaugggc uagccauuga ggugacucac      720

cuccaucaga cucggaccca ccagggccag caugucagga uuagccgauc guuaccucaa      780

gggaguggga auugggccca gcuccggccc cuccugguca ccuuuggcca ugauggccgg      840

ggccaugccu ugacccgacg ccggagggcc aagcguagcc cuaagcauca cucacagcgg      900

gccaggaaga agaauaagaa cugccggcgc cacucgcucu auguggacuu cagcgaugug      960

ggcuggaaug acuggauugu ggccccacca ggcuaccagg ccuucuacug ccauggggac     1020

ugccccuuuc cacuggcuga ccaccucaac ucaaccaacc augccauugu gcagacccug     1080

gucaauucug ucaauuccag uauccccaaa gccuguugug ugcccacuga acugagugcc     1140

aucuccaugc uguaccugga ugaguaugau aaggugguac ugaaaaauua ucaggagaug     1200

guaguagagg gaugugggug ccgcuga                                         1227


<210>  5968
<211>  1542
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001709.1__HsBMP6

<400>  5968
augccggggc uggggcggag ggcgcagugg cugugcuggu ggugggggcu gcugugcagc       60

ugcugcgggc ccccgccgcu gcggccgccc uugcccgcug ccgcggccgc cgccgccggg      120

gggcagcugc ugggggacgg cgggagcccc ggccgcacgg agcagccgcc gccgucgccg      180

caguccuccu cgggcuuccu guaccggcgg cucaagacgc aggagaagcg ggagaugcag      240

aaggagaucu ugucggugcu ggggcucccg caccggcccc ggccccugca cggccuccaa      300

cagccgcagc ccccggcgcu ccggcagcag gaggagcagc agcagcagca gcagcugccu      360

cgcggagagc ccccucccgg gcgacugaag uccgcgcccc ucuucaugcu ggaucuguac      420

aacgcccugu ccgccgacaa cgacgaggac ggggcgucgg agggggagag gcagcagucc      480

uggccccacg aagcagccag cucgucccag cgucggcagc cgcccccggg cgccgcgcac      540

ccgcucaacc gcaagagccu ucuggccccc ggaucuggca gcggcggcgc guccccacug      600

accagcgcgc aggacagcgc cuuccucaac gacgcggaca uggucaugag cuuugugaac      660

cugguggagu acgacaagga guucuccccu cgucagcgac accacaaaga guucaaguuc      720

aacuuauccc agauuccuga gggugaggug gugacggcug cagaguuccg caucuacaag      780

gacuguguua uggggaguuu uaaaaaccaa acuuuucuua ucagcauuua ucaagucuua      840

caggagcauc agcacagaga cucugaccug uuuuuguugg acacccgugu aguaugggcc      900

ucagaagaag gcuggcugga auuugacauc acggccacua gcaaucugug gguugugacu      960

ccacagcaua acauggggcu ucagcugagc guggugacaa gggauggagu ccacguccac     1020

ccccgagccg caggccuggu gggcagagac ggcccuuacg acaagcagcc cuucauggug     1080

gcuuucuuca aagugaguga ggugcacgug cgcaccacca ggucagccuc cagccggcgc     1140

cgacaacaga gucguaaucg cucuacccag ucccaggacg uggcgcgggu cuccagugcu     1200

ucagauuaca acagcaguga auugaaaaca gccugcagga agcaugagcu guaugugagu     1260

uuccaagacc ugggauggca ggacuggauc auugcaccca agggcuaugc ugccaauuac     1320

ugugauggag aaugcuccuu cccacucaac gcacacauga augcaaccaa ccacgcgauu     1380

gugcagaccu ugguucaccu uaugaacccc gaguaugucc ccaaaccgug cugugcgcca     1440

acuaagcuaa augccaucuc gguucuuuac uuugaugaca acuccaaugu cauucugaaa     1500

aaauacagga auaugguugu aagagcuugu ggaugccacu aa                        1542


<210>  5969
<211>  1296
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001710.1__HsBMP7

<400>  5969
augcacgugc gcucacugcg agcugcggcg ccgcacagcu ucguggcgcu cugggcaccc       60

cuguuccugc ugcgcuccgc ccuggccgac uucagccugg acaacgaggu gcacucgagc      120

uucauccacc ggcgccuccg cagccaggag cggcgggaga ugcagcgcga gauccucucc      180

auuuugggcu ugccccaccg cccgcgcccg caccuccagg gcaagcacaa cucggcaccc      240

auguucaugc uggaccugua caacgccaug gcgguggagg agggcggcgg gcccggcggc      300

cagggcuucu ccuaccccua caaggccguc uucaguaccc agggcccccc ucuggccagc      360

cugcaagaua gccauuuccu caccgacgcc gacaugguca ugagcuucgu caaccucgug      420

gaacaugaca aggaguucuu ccacccacgc uaccaccauc gagaguuccg guuugaucuu      480

uccaagaucc cagaagggga agcugucacg gcagccgagu uccggaucua caaggacuac      540

auccgggaac gcuucgacaa ugagacguuc cggaucagcg uuuaucaggu gcuccaggag      600

cacuugggca gggaaucgga ucucuuccug cucgacagcc guacccucug ggccucggag      660

gagggcuggc ugguguuuga caucacagcc accagcaacc acuggguggu caauccgcgg      720

cacaaccugg gccugcagcu cucgguggag acgcuggaug ggcagagcau caaccccaag      780

uuggcgggcc ugauugggcg gcacgggccc cagaacaagc agcccuucau gguggcuuuc      840

uucaaggcca cggaggucca cuuccgcagc auccggucca cggggagcaa acagcgcagc      900

cagaaccgcu ccaagacgcc caagaaccag gaagcccugc ggauggccaa cguggcagag      960

aacagcagca gcgaccagag gcaggccugu aagaagcacg agcuguaugu cagcuuccga     1020

gaccugggcu ggcaggacug gaucaucgcg ccugaaggcu acgccgccua cuacugugag     1080

ggggagugug ccuucccucu gaacuccuac augaacgcca ccaaccacgc caucgugcag     1140

acgcuggucc acuucaucaa cccggaaacg gugcccaagc ccugcugugc gcccacgcag     1200

cucaaugcca ucuccguccu cuacuucgau gacagcucca acgucauccu gaagaaauac     1260

agaaacaugg ugguccgggc cuguggcugc cacuag                               1296


<210>  5970
<211>  300
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_006264.2__HsCCL7

<400>  5970
augaaagccu cugcagcacu ucugugucug cugcucacag cagcugcuuu cagcccccag       60

gggcuugcuc agccaguugg gauuaauacu ucaacuaccu gcugcuacag auuuaucaau      120

aagaaaaucc cuaagcagag gcuggagagc uacagaagga ccaccaguag ccacuguccc      180

cgggaagcug uaaucuucaa gaccaaacug gacaaggaga ucugugcuga ccccacacag      240

aagugggucc aggacuuuau gaagcaccug gacaagaaaa cccaaacucc aaagcuguga      300


<210>  5971
<211>  3624
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001954.2__HsEGF

<400>  5971
augcugcuca cucuuaucau ucuguugcca guaguuucaa aauuuaguuu uguuagucuc       60

ucagcaccgc agcacuggag cuguccugaa gguacucucg caggaaaugg caauucuacu      120

uguguggguc cugcacccuu cuuaauuuuc ucccauggaa auaguaucuu uaggauugac      180

acagaaggaa ccaauuauga gcaauuggug guggaugcug gugucucagu gaucauggau      240

uuucauuaua augagaaaag aaucuauugg guggauuuag aaagacaacu uuugcaaaga      300

guuuuucuga augggucaag gcaagagaga guauguaaua uagagaaaaa uguuucugga      360

auggcaauaa auuggauaaa ugaagaaguu auuuggucaa aucaacagga aggaaucauu      420

acaguaacag auaugaaagg aaauaauucc cacauucuuu uaagugcuuu aaaauauccu      480

gcaaauguag caguugaucc aguagaaagg uuuauauuuu ggucuucaga gguggcugga      540

agccuuuaua gagcagaucu cgauggugug ggagugaagg cucuguugga gacaucagag      600

aaaauaacag cugugucauu ggaugugcuu gauaagcggc uguuuuggau ucaguacaac      660

agagaaggaa gcaauucucu uauuugcucc ugugauuaug auggagguuc uguccacauu      720

aguaaacauc caacacagca uaauuuguuu gcaauguccc uuuuugguga ccguaucuuc      780

uauucaacau ggaaaaugaa gacaauuugg auagccaaca aacacacugg aaaggacaug      840

guuagaauua accuccauuc aucauuugua ccacuuggug aacugaaagu agugcaucca      900

cuugcacaac ccaaggcaga agaugacacu ugggagccug agcagaaacu uugcaaauug      960

aggaaaggaa acugcagcag cacugugugu gggcaagacc uccagucaca cuugugcaug     1020

ugugcagagg gauacgcccu aagucgagac cggaaguacu gugaagaugu uaaugaaugu     1080

gcuuuuugga aucauggcug uacucuuggg uguaaaaaca ccccuggauc cuauuacugc     1140

acgugcccug uaggauuugu ucugcuuccu gaugggaaac gaugucauca acuuguuucc     1200

uguccacgca augugucuga augcagccau gacuguguuc ugacaucaga aggucccuua     1260

uguuucuguc cugaaggcuc agugcuugag agagauggga aaacauguag cgguuguucc     1320

ucacccgaua augguggaug uagccagcuc ugcguuccuc uuagcccagu auccugggaa     1380

ugugauugcu uuccugggua ugaccuacaa cuggaugaaa aaagcugugc agcuucagga     1440

ccacaaccau uuuugcuguu ugccaauucu caagauauuc gacacaugca uuuugaugga     1500

acagacuaug gaacucugcu cagccagcag augggaaugg uuuaugcccu agaucaugac     1560

ccuguggaaa auaagauaua cuuugcccau acagcccuga aguggauaga gagagcuaau     1620

auggaugguu cccagcgaga aaggcuuauu gaggaaggag uagaugugcc agaaggucuu     1680

gcuguggacu ggauuggccg uagauucuau uggacagaca gagggaaauc ucugauugga     1740

aggagugauu uaaaugggaa acguuccaaa auaaucacua aggagaacau cucucaacca     1800

cgaggaauug cuguucaucc aauggccaag agauuauucu ggacugauac agggauuaau     1860

ccacgaauug aaaguucuuc ccuccaaggc cuuggccguc ugguuauagc cagcucugau     1920

cuaaucuggc ccaguggaau aacgauugac uucuuaacug acaaguugua cuggugcgau     1980

gccaagcagu cugugauuga aauggccaau cuggaugguu caaaacgccg aagacuuacc     2040

cagaaugaug uaggucaccc auuugcugua gcaguguuug aggauuaugu gugguucuca     2100

gauugggcua ugccaucagu aaugagagua aacaagagga cuggcaaaga uagaguacgu     2160

cuccaaggca gcaugcugaa gcccucauca cugguugugg uucauccauu ggcaaaacca     2220

ggagcagauc ccugcuuaua ucaaaacgga ggcugugaac auauuugcaa aaagaggcuu     2280

ggaacugcuu gguguucgug ucgugaaggu uuuaugaaag ccucagaugg gaaaacgugu     2340

cuggcucugg auggucauca gcuguuggca ggaggugaag uugaucuaaa gaaccaagua     2400

acaccauugg acaucuuguc caagacuaga gugucagaag auaacauuac agaaucucaa     2460

cacaugcuag uggcugaaau caugguguca gaucaagaug acugugcucc ugugggaugc     2520

agcauguaug cucgguguau uucagaggga gaggaugcca caugucagug uuugaaagga     2580

uuugcugggg auggaaaacu auguucugau auagaugaau gugagauggg ugucccagug     2640

ugccccccug ccuccuccaa gugcaucaac accgaaggug guuaugucug ccggugcuca     2700

gaaggcuacc aaggagaugg gauucacugu cuugauauug augagugcca acugggggag     2760

cacagcugug gagagaaugc cagcugcaca aauacagagg gaggcuauac cugcaugugu     2820

gcuggacgcc ugucugaacc aggacugauu ugcccugacu cuacuccacc cccucaccuc     2880

agggaagaug accaccacua uuccguaaga aauagugacu cugaaugucc ccugucccac     2940

gauggguacu gccuccauga uggugugugc auguauauug aagcauugga caaguaugca     3000

ugcaacugug uuguuggcua caucggggag cgaugucagu accgagaccu gaaguggugg     3060

gaacugcgcc acgcuggcca cgggcagcag cagaagguca ucgugguggc ugucugcgug     3120

guggugcuug ucaugcugcu ccuccugagc cugugggggg cccacuacua caggacucag     3180

aagcugcuau cgaaaaaccc aaagaauccu uaugaggagu cgagcagaga ugugaggagu     3240

cgcaggccug cugacacuga ggaugggaug uccucuugcc cucaaccuug guuugugguu     3300

auaaaagaac accaagaccu caagaauggg ggucaaccag uggcugguga ggauggccag     3360

gcagcagaug ggucaaugca accaacuuca uggaggcagg agccccaguu auguggaaug     3420

ggcacagagc aaggcugcug gauuccagua uccagugaua agggcuccug uccccaggua     3480

auggagcgga gcuuucauau gcccuccuau gggacacaga cccuugaagg gggugucgag     3540

aagccccauu cucuccuauc agcuaaccca uuauggcaac aaagggcccu ggacccacca     3600

caccaaaugg agcugacuca guga                                            3624


<210>  5972
<211>  510
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001423.1__HsEREG

<400>  5972
augaccgcgg ggaggaggau ggagaugcuc ugugccggca gggucccugc gcugcugcuc       60

ugccuggguu uccaucuucu acaggcaguc cucaguacaa cugugauucc aucauguauc      120

ccaggagagu ccagugauaa cugcacagcu uuaguucaga cagaagacaa uccacgugug      180

gcucaagugu caauaacaaa guguagcucu gacaugaaug gcuauuguuu gcauggacag      240

ugcaucuauc ugguggacau gagucaaaac uacugcagau gugaaguggg uuauacuggu      300

guccgaugug aacacuucuu uuuaaccguc caccaaccuu uaagcaaaga auauguggcu      360

uugaccguga uucuuauuau uuuguuucuu aucacagucg ucgguuccac auauuauuuc      420

ugcagauggu acagaaaucg aaaaaguaaa gaaccaaaga aggaauauga gagaguuacc      480

ucaggggauc cagaguugcc gcaagucuga                                       510


<210>  5973
<211>  867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001997.5__HsFGF2

<400>  5973
auggugggug uggggggugg agauguagaa gaugugacgc cgcggcccgg cgggugccag       60

auuagcggac gcggugcccg cgguugcaac gggaucccgg gcgcugcagc uugggaggcg      120

gcucucccca ggcggcgucc gcggagacac ccauccguga accccagguc ccgggccgcc      180

ggcucgccgc gcaccagggg ccggcggaca gaagaacggc cgagcggcuc gaggcugggg      240

gaccgcgggc gcggccgcgc gcugccgggc gggaggcugg ggggccgggg ccggggccgu      300

gccccggagc gggucggagg ccggggccgg ggccggggga cggcggcucc ccgcgcggcu      360

ccagcggcuc ggggaucccg gccgggcccc gcagggacca uggcagccgg gagcaucacc      420

acgcugcccg ccuugcccga ggauggcggc agcggcgccu ucccgcccgg ccacuucaag      480

gaccccaagc ggcuguacug caaaaacggg ggcuucuucc ugcgcaucca ccccgacggc      540

cgaguugacg ggguccggga aaagagcgac ccucacauca agcuacaacu ucaagcagaa      600

gagagaggag uugugucuau caaaggagug ugugcuaacc guuaccuggc uaugaaggaa      660

gauggaagau uacuggcuuc uaaauguguu acggaugagu guuucuuuuu ugaacgauug      720

gaaucuaaua acuacaauac uuaccgguca aggaaauaca ccaguuggua uguggcacug      780

aaacgaacug ggcaguauaa acuuggaucc aaaacaggac cugggcagaa agcuauacuu      840

uuucuuccaa ugucugcuaa gagcuga                                          867


<210>  5974
<211>  585
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002000.1__HsFGF7

<400>  5974
augcacaaau ggauacugac auggauccug ccaacuuugc ucuacagauc augcuuucac       60

auuaucuguc uaguggguac uauaucuuua gcuugcaaug acaugacucc agagcaaaug      120

gcuacaaaug ugaacuguuc cagcccugag cgacacacaa gaaguuauga uuacauggaa      180

ggaggggaua uaagagugag aagacucuuc ugucgaacac agugguaccu gaggaucgau      240

aaaagaggca aaguaaaagg gacccaagag augaagaaua auuacaauau cauggaaauc      300

aggacagugg caguuggaau uguggcaauc aaaggggugg aaagugaguu cuaucuugca      360

augaacaagg aaggaaaacu cuaugcaaag aaagaaugca augaagauug uaacuucaaa      420

gaacuaauuc uggaaaacca uuacaacaca uaugcaucag cuaaauggac acacaacgga      480

ggggaaaugu uuguugccuu aaaucaaaag gggauuccug uaagaggaaa aaaaacgaag      540

aaagaacaaa aaacagccca cuuucuuccu auggcaauaa cuuaa                      585


<210>  5975
<211>  2187
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000592.3__HsHGF

<400>  5975
auguggguga ccaaacuccu gccagcccug cugcugcagc auguccuccu gcaucuccuc       60

cugcucccca ucgccauccc cuaugcagag ggacaaagga aaagaagaaa uacaauucau      120

gaguucaaaa aaucagcaaa gacuacccua aucaaaauag auccagcacu gaagauaaaa      180

accaaaaaag ugaauacugc agaccaaugu gcuaauagau guacuaggaa uaaaggacuu      240

ccauucacuu gcaaggcuuu uguuuuugau aaagcaagaa aacaaugccu cugguucccc      300

uucaauagca ugucaagugg agugaaaaaa gaauuuggcc augaauuuga ccucuaugaa      360

aacaaagacu acauuagaaa cugcaucauu gguaaaggac gcagcuacaa gggaacagua      420

ucuaucacua agaguggcau caaaugucag cccuggaguu ccaugauacc acacgaacac      480

agcuuuuugc cuucgagcua ucgggguaaa gaccuacagg aaaacuacug ucgaaauccu      540

cgaggggaag aagggggacc cugguguuuc acaagcaauc cagagguacg cuacgaaguc      600

ugugacauuc cucaguguuc agaaguugaa ugcaugaccu gcaaugggga gaguuaucga      660

ggucucaugg aucauacaga aucaggcaag auuugucagc gcugggauca ucagacacca      720

caccggcaca aauucuugcc ugaaagauau cccgacaagg gcuuugauga uaauuauugc      780

cgcaaucccg auggccagcc gaggccaugg ugcuauacuc uugacccuca cacccgcugg      840

gaguacugug caauuaaaac augcgcugac aauacuauga augacacuga uguuccuuug      900

gaaacaacug aaugcaucca aggucaagga gaaggcuaca ggggcacugu caauaccauu      960

uggaauggaa ucccauguca gcguugggau ucucaguauc cucacgagca ugacaugacu     1020

ccugaaaauu ucaagugcaa ggaccuacga gaaaauuacu gccgaaaucc agaugggucu     1080

gaaucacccu gguguuuuac cacugaucca aacauccgag uuggcuacug cucccaaauu     1140

ccaaacugug auaugucaca uggacaagau uguuaucgug ggaauggcaa aaauuauaug     1200

ggcaacuuau cccaaacaag aucuggacua acauguucaa ugugggacaa gaacauggaa     1260

gacuuacauc gucauaucuu cugggaacca gaugcaagua agcugaauga gaauuacugc     1320

cgaaauccag augaugaugc ucauggaccc uggugcuaca cgggaaaucc acucauuccu     1380

ugggauuauu gcccuauuuc ucguugugaa ggugauacca caccuacaau agucaauuua     1440

gaccaucccg uaauaucuug ugccaaaacg aaacaauugc gaguuguaaa ugggauucca     1500

acacgaacaa acauaggaug gaugguuagu uugagauaca gaaauaaaca uaucugcgga     1560

ggaucauuga uaaaggagag uuggguucuu acugcacgac aguguuuccc uucucgagac     1620

uugaaagauu augaagcaug gcuuggaauc caugaugucc acggaagagg agaugagaaa     1680

ugcaaacagg uucucaaugu uucccagcug guauauggcc cugaaggauc agaucugguu     1740

uuaaugaagc uggccaggcc ugcuguccug gaugauuuug uuaguacgau ugauuuaccu     1800

aauuauggau gcacaauucc ugaaaagacc aguugcagug uuuauggcug gggcuacacu     1860

ggauugauca acuaugaugg ccuauuacga guggcacauc ucuauauaau gggaaaugag     1920

aaaugcagcc agcaucaucg agggaaggug acucugaaug agucugaaau augugcuggg     1980

gcugaaaaga uuggaucagg accaugugag ggggauuaug guggcccacu uguuugugag     2040

caacauaaaa ugagaauggu ucuugguguc auuguuccug gucguggaug ugccauucca     2100

aaucguccug guauuuuugu ccgaguagca uauuaugcaa aauggauaca caaaauuauu     2160

uuaacauaua agguaccaca gucauag                                         2187


<210>  5976
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_005336.3 __HsHSPA1A

<400>  5976
auggccaaag ccgcggcgau cggcaucgac cugggcacca ccuacuccug cgugggggug       60

uuccaacacg gcaaggugga gaucaucgcc aacgaccagg gcaaccgcac cacccccagc      120

uacguggccu ucacggacac cgagcggcuc aucggggaug cggccaagaa ccagguggcg      180

cugaacccgc agaacaccgu guuugacgcg aagcggcuga uuggccgcaa guucggcgac      240

ccgguggugc agucggacau gaagcacugg ccuuuccagg ugaucaacga cggagacaag      300

cccaaggugc aggucagcua caagggggag accaaggcau ucuaccccga ggagaucucg      360

uccauggugc ugaccaagau gaaggagauc gccgaggcgu accugggcua cccggugacc      420

aacgcgguga ucaccgugcc ggccuacuuc aacgacucgc agcgccaggc caccaaggau      480

gcggguguga ucgcggggcu caacgugcug cggaucauca acgagcccac ggccgccgcc      540

aucgccuacg gccuggacag aacgggcaag ggggagcgca acgugcucau cuuugaccug      600

ggcgggggca ccuucgacgu guccauccug acgaucgacg acggcaucuu cgaggugaag      660

gccacggccg gggacaccca ccuggguggg gaggacuuug acaacaggcu ggugaaccac      720

uucguggagg aguucaagag aaaacacaag aaggacauca gccagaacaa gcgagccgug      780

aggcggcugc gcaccgccug cgagagggcc aagaggaccc ugucguccag cacccaggcc      840

agccuggaga ucgacucccu guuugagggc aucgacuucu acacguccau caccagggcg      900

agguucgagg agcugugcuc cgaccuguuc cgaagcaccc uggagcccgu ggagaaggcu      960

cugcgcgacg ccaagcugga caaggcccag auucacgacc ugguccuggu cgggggcucc     1020

acccgcaucc ccaaggugca gaagcugcug caggacuucu ucaacgggcg cgaccugaac     1080

aagagcauca accccgacga ggcuguggcc uacggggcgg cggugcaggc ggccauccug     1140

augggggaca aguccgagaa cgugcaggac cugcugcugc uggacguggc uccccugucg     1200

cuggggcugg agacggccgg aggcgugaug acugcccuga ucaagcgcaa cuccaccauc     1260

cccaccaagc agacgcagau cuucaccacc uacuccgaca accaacccgg ggugcugauc     1320

cagguguacg agggcgagag ggccaugacg aaagacaaca aucuguuggg gcgcuucgag     1380

cugagcggca ucccuccggc ccccaggggc gugccccaga ucgaggugac cuucgacauc     1440

gaugccaacg gcauccugaa cgucacggcc acggacaaga gcaccggcaa ggccaacaag     1500

aucaccauca ccaacgacaa gggccgccug agcaaggagg agaucgagcg cauggugcag     1560

gaggcggaga aguacaaagc ggaggacgag gugcagcgcg agaggguguc agccaagaac     1620

gcccuggagu ccuacgccuu caacaugaaa agcgccgugg aggaugaggg gcucaagggc     1680

aagaucagcg aggcggacaa gaagaaggug cuggacaagu gucaagaggu caucucgugg     1740

cuggacgcca acaccuuggc cgagaaggac gaguuugagc acaagaggaa ggagcuggag     1800

caggucugua accccaucau cagcggacug uaccagggug ccgguggucc cgggccuggg     1860

ggcuucgggg cucagggucc caagggaggg ucugggucag gccccaccau ugaggaggua     1920

gauuag                                                                1926


<210>  5977
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_005337.2 __HsHSPA1B

<400>  5977
auggccaaag ccgcggcgau cggcaucgac cugggcacca ccuacuccug cgugggggug       60

uuccaacacg gcaaggugga gaucaucgcc aacgaccagg gcaaccgcac cacccccagc      120

uacguggccu ucacggacac cgagcggcuc aucggggaug cggccaagaa ccagguggcg      180

cugaacccgc agaacaccgu guuugacgcg aagcggcuga uuggccgcaa guucggcgac      240

ccgguggugc agucggacau gaagcacugg ccuuuccagg ugaucaacga cggagacaag      300

cccaaggugc aggucagcua caagggggag accaaggcau ucuaccccga ggagaucucg      360

uccauggugc ugaccaagau gaaggagauc gccgaggcgu accugggcua cccggugacc      420

aacgcgguga ucaccgugcc ggccuacuuc aacgacucgc agcgccaggc caccaaggau      480

gcggguguga ucgcggggcu caacgugcug cggaucauca acgagcccac ggccgccgcc      540

aucgccuacg gccuggacag aacgggcaag ggggagcgca acgugcucau cuuugaccug      600

ggcgggggca ccuucgacgu guccauccug acgaucgacg acggcaucuu cgaggugaag      660

gccacggccg gggacaccca ccuggguggg gaggacuuug acaacaggcu ggugaaccac      720

uucguggagg aguucaagag aaaacacaag aaggacauca gccagaacaa gcgagccgug      780

aggcggcugc gcaccgccug cgagagggcc aagaggaccc ugucguccag cacccaggcc      840

agccuggaga ucgacucccu guuugagggc aucgacuucu acacguccau caccagggcg      900

agguucgagg agcugugcuc cgaccuguuc cgaagcaccc uggagcccgu ggagaaggcu      960

cugcgcgacg ccaagcugga caaggcccag auucacgacc ugguccuggu cgggggcucc     1020

acccgcaucc ccaaggugca gaagcugcug caggacuucu ucaacgggcg cgaccugaac     1080

aagagcauca accccgacga ggcuguggcc uacggggcgg cggugcaggc ggccauccug     1140

augggggaca aguccgagaa cgugcaggac cugcugcugc uggacguggc uccccugucg     1200

cuggggcugg agacggccgg aggcgugaug acugcccuga ucaagcgcaa cuccaccauc     1260

cccaccaagc agacgcagau cuucaccacc uacuccgaca accaacccgg ggugcugauc     1320

cagguguacg agggcgagag ggccaugacg aaagacaaca aucuguuggg gcgcuucgag     1380

cugagcggca ucccuccggc ccccaggggc gugccccaga ucgaggugac cuucgacauc     1440

gaugccaacg gcauccugaa cgucacggcc acggacaaga gcaccggcaa ggccaacaag     1500

aucaccauca ccaacgacaa gggccgccug agcaaggagg agaucgagcg cauggugcag     1560

gaggcggaga aguacaaagc ggaggacgag gugcagcgcg agaggguguc agccaagaac     1620

gcccuggagu ccuacgccuu caacaugaaa agcgccgugg aggaugaggg gcucaagggc     1680

aagaucagcg aggcggacaa gaagaagguu cuggacaagu gucaagaggu caucucgugg     1740

cuggacgcca acaccuuggc cgagaaggac gaguuugagc acaagaggaa ggagcuggag     1800

caggucugua accccaucau cagcggacug uaccagggug ccgguggucc cgggccuggc     1860

ggcuucgggg cucagggucc caagggaggg ucugggucag gcccuaccau ugaggaggug     1920

gauuag                                                                1926


<210>  5978
<211>  1926
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_005518.3 __HsHSPA1L

<400>  5978
auggcuacug ccaagggaau cgccauaggc aucgaccugg gcaccaccua cuccugugug       60

gggguguucc agcacggcaa gguggagauc aucgccaacg accagggcaa ccgcaccacc      120

cccagcuacg uggccuucac agacaccgag cggcucauug gggaugcggc caagaaccag      180

guagcaauga auccccagaa cacuguuuuu gaugcuaaac gucugaucgg caggaaauuu      240

aaugauccug uuguacaagc agauaugaaa cuuuggccuu uucaagugau uaaugaagga      300

ggcaagccca aaguccuugu guccuacaaa ggggagaaua aagcauucua cccugaggaa      360

aucucuucga ugguauugac uaaguugaag gagacugcug aggccuuuuu gggccacccu      420

gucaccaaug cagugauuac cgugccagcc uauuucaaug acucucaacg ucaggcuacu      480

aaggaugcag gagugauugc uggacuuaau gugcuaagaa ucaucaauga gcccacggcu      540

gcugccauug ccuaugguuu agauaaagga ggucaaggag aacgacaugu ccugauuuuu      600

gaucugggug gaggcacauu ugauguguca auucugacca uagaugaugg gauuuuugag      660

guaaaggcca cugcugggga cacucaccug gguggggagg acuuugacaa caggcuugug      720

agccacuucg uggaggaguu caagaggaaa cacaaaaagg acaucagcca gaacaagcga      780

gccgugaggc ggcugcgcac cgccugcgag agggccaaga ggacccuguc guccagcacc      840

caggccaacc uagaaauuga uucacuuuau gaaggcauug acuucuauac auccaucacc      900

agagcucgau uugaagaguu gugugcagac cuguuuaggg guacccugga gccuguagaa      960

aaagcgcuuc gggaugccaa gauggauaag gcuaaaaucc augacauugu uuuaguaggg     1020

ggcuccaccc gcauccccaa ggugcagcgg cugcuucagg acuacuucaa uggacgugau     1080

cucaacaaga gcaucaaccc ugaugaggcc guagcauaug gggcugcggu acaagcagcc     1140

auccugaugg gggacaaguc ugagaaggua caggaccugc ugcugcugga cguggcuccc     1200

cugucccugg ggcuggagac ggcugggggc gugaugacug cccugauaaa gcgcaacucc     1260

accaucccca ccaagcagac acagauuuuc accaccuacu cugacaacca acccggggug     1320

cugauccagg uguaugaggg cgagagggcc augacaaagg acaacaaccu gcuggggcgg     1380

uuugaccuga cuggaauccc uccagcaccc aggggaguuc cucagaucga ggugacguuu     1440

gacauugaug ccaaugguau ucucaauguc acagccacgg acaagagcac cggcaaggug     1500

aacaagauca ccaucaccaa ugacaagggc cgccugagca aggaggagau ugagcgcaug     1560

guucuggaug cugagaaaua uaaagcugaa gaugaggucc agagggagaa aauugcugca     1620

aagaaugccu uagaauccua ugcuuuuaac augaagagug uugugaguga ugaagguuug     1680

aagggcaaga uuagugaguc ugauaaaaau aaaauauugg auaaaugcaa cgagcuccuu     1740

ucguggcugg aggucaauca acuggcagag aaagaugagu uugaucauaa gagaaaggaa     1800

uuggagcaga uguguaaccc uaucaucaca aaacucuacc aaggaggaug cacugggccu     1860

gccugcggaa caggguaugu gccuggaagg ccugccacag gccccacaau ugaagaagua     1920

gauuaa                                                                1926


<210>  5979
<211>  2523
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002145.3 __HsHSPA4

<400>  5979
augucggugg ugggcauaga ccugggcuuc cagagcugcu acgucgcugu ggcccgcgcc       60

ggcggcaucg agacuaucgc uaaugaguau agcgaccgcu gcacgccggc uugcauuucu      120

uuugguccua agaaucguuc aauuggagca gcagcuaaaa gccagguaau uucuaaugca      180

aagaacacag uccaaggauu uaaaagauuc cauggccgag cauucucuga uccauuugug      240

gaggcagaaa aaucuaaccu ugcauaugau auugugcagu ugccuacagg auuaacaggu      300

auaaagguga cauauaugga ggaagaacga aauuuuacca cugagcaagu gacugccaug      360

cuuuugucca aacugaagga gacagccgaa aguguucuua agaagccugu aguugacugu      420

guuguuucgg uuccuuguuu cuauacugau gcagaaagac gaucagugau ggaugcaaca      480

cagauugcug gucuuaauug cuugcgauua augaaugaaa ccacugcagu ugcucuugca      540

uauggaaucu auaagcagga ucuuccugcc uuagaagaga aaccaagaaa uguaguuuuu      600

guagacaugg gccacucugc uuaucaaguu ucuguaugug cauuuaauag aggaaaacug      660

aaaguucugg ccacugcauu ugacacgaca uugggaggua gaaaauuuga ugaaguguua      720

guaaaucacu ucugugaaga auuugggaag aaauacaagc uagacauuaa guccaaaauc      780

cgugcauuau uacgacucuc ucaggagugu gagaaacuca agaaauugau gagugcaaau      840

gcuucagauc ucccuuugag cauugaaugu uuuaugaaug auguugaugu aucuggaacu      900

augaauagag gcaaauuucu ggagaugugc aaugaucucu uagcuagagu ggagccacca      960

cuucguagug uuuuggaaca aaccaaguua aagaaagaag auauuuaugc aguggagaua     1020

guugguggug cuacacgaau cccugcggua aaagagaaga ucagcaaauu uuucgguaaa     1080

gaacuuagua caacauuaaa ugcugaugaa gcugucacuc gaggcugugc auugcagugu     1140

gccaucuuau cgccugcuuu caaagucaga gaauuuucua ucacugaugu aguaccauau     1200

ccaauaucuc ugagauggaa cucuccagcu gaagaagggu caagugacug ugaagucuuu     1260

uccaaaaauc augcugcucc uuucucuaaa guucuuacau uuuauagaaa ggaaccuuuc     1320

acucuugagg ccuacuacag cucuccucag gauuugcccu auccagaucc ugcuauagcu     1380

caguuuucag uucagaaagu cacuccucag ucugauggcu ccaguucaaa agugaaaguc     1440

aaaguucgag uaaaugucca uggcauuuuc agugugucca gugcaucuuu aguggagguu     1500

cacaagucug aggaaaauga ggagccaaug gaaacagauc agaaugcaaa ggaggaagag     1560

aagaugcaag uggaccagga ggaaccacau guugaagaac aacagcagca gacaccagca     1620

gaaaauaagg cagagucuga agaaauggag accucucaag cuggauccaa ggauaaaaag     1680

auggaccaac caccccaagc caagaaggca aaagugaaga ccaguacugu ggaccugcca     1740

aucgagaauc agcuauuaug gcagauagac agagagaugc ucaacuugua cauugaaaau     1800

gaggguaaga ugaucaugca ggauaaacug gagaaggagc ggaaugaugc uaagaacgca     1860

guggaggaau auguguauga aaugagagac aagcugagug gugaauauga gaaguuugug     1920

agugaagaug aucguaacag uuuuacuuug aaacuggaag auacugaaaa uugguuguau     1980

gaggauggag aagaccagcc aaagcaaguu uauguugaua aguuggcuga auuaaaaaau     2040

cuaggucaac cuauuaagau acguuuccag gaaucugaag aacgaccaaa auuauuugaa     2100

gaacuaggga aacagaucca acaguauaug aaaauaauca gcucuuucaa aaacaaggag     2160

gaccaguaug aucauuugga ugcugcugac augacaaagg uagaaaaaag cacaaaugaa     2220

gcaauggagu ggaugaauaa caagcuaaau cugcagaaca agcagaguuu gaccauggau     2280

ccaguuguca agucaaaaga gauugaagcu aaaauuaagg agcugacaag uacuuguagc     2340

ccuauaauuu caaagcccaa acccaaagug gaaccuccaa aagaggaaca aaaaaaugca     2400

gagcagaaug gaccagugga uggacaagga gacaacccag gcccccaggc ugcugagcag     2460

gguacagaca cagcugugcc uucggauuca gacaagaagc ugccugaaau ggacauugau     2520

uga                                                                   2523


<210>  5980
<211>  2520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_055093.2 __HsHSPA4L

<400>  5980
augucugugg uuggcauuga ccucggcuuu cucaacugcu acauugcugu cgcgagaagu       60

ggcggcaucg agaccaucgc caaugaguac agcgacaggu guaccccggc cuguauauca      120

uugggaucaa gaacucgagc cauuggaaau gcagcaaaga gccagauagu cacgaacgua      180

agaaauacaa uucauggcuu caaaaagcug caugggcgau cauuugauga ucccauugug      240

caaacugaaa ggaucaggcu ucccuaugaa cugcagaaaa ugccuaaugg aagugcagga      300

guuaaggugc gguacuuaga ggaagagaga ccuuuugcaa uugagcaagu uacuggaaug      360

cuguuagcca agcugaaaga gacuucagaa aaugcuuuga agaaaccagu ggcugacugu      420

gugauuucaa uuccuagcuu uuuuacugau gccgagagaa gaucugugau ggcugcagcc      480

cagguugcag gcuuaaauug uuuaagguug augaaugaaa cuacugcagu ugcacuggcg      540

uauggaauuu auaaacagga ucuuccccca uuagaugaga aaccaagaaa uguaguauuu      600

auugauaugg gacauucugc cuaucagguc uugguuugug cuuuuaacaa aggaaaacuu      660

aaagucuugg cuacuaccuu ugauccauau uuggguggca ggaacuuuga ugaggcuuua      720

guagacuacu ucugugauga guucaagacc aaauauaaga uaaaugugaa agaaaacucu      780

cgggccuugu ugcguuuaua ucaggaaugu gaaaaacuaa agaagcuaau gagugcaaau      840

gcaucagauc uuccauugaa cauugagugu uucaugaaug accuugaugu uucuaguaaa      900

augaacaggg cucaauuuga acaacugugu gcuucccuuu uggccagggu ugaaccaccu      960

uuaaaagcag uaauggaaca agcuaacuua caacgugaag acauuaguag uauagaaauu     1020

guaggaggag caacacgaau cccugcagug aaagaacaaa ucacuaaauu cuuucuuaaa     1080

gacauaagua ccacauuaaa ugcugaugaa gcuguugcaa gaggaugugc guuacagugu     1140

gcgauucucu caccagcauu uaaagugcgu gaauuuucca uaacagaccu uguucccuau     1200

ucaaucacau uaagguggaa gaccucuuuu gaagauggaa guggggaaug ugaaguuuuc     1260

uguaagaacc auccugcccc auucucaaaa gucauuacuu uccacaagaa ggaaccauuu     1320

gaacuagaag cauuuuauac uaauuuacau gaagugccuu auccugaugc aagaauuggg     1380

agcuucacua uucagaaugu uuuuccacag ucugauggug auaguuccaa agugaagguu     1440

aaaguucgug uuaacaucca uggaaucuuc aguguggcua gcgcaucagu aauugagaag     1500

caaaauuugg aaggcgauca cagugaugcu ccaauggaga cagaaacuuc auuuaaaaau     1560

gaaaacaaag auaauaugga uaaaaugcag guugaucaag aagaagggca ucaaaaaugu     1620

caugcugaac acacuccaga agaggaaauu gaucauacag gagccaaaac aaagucagcu     1680

gucucagaca aacaagaccg auuaaaucag acacuuaaaa aaggaaaagu caaaaguauu     1740

gaucuaccga uccagaguag ccuauguaga caacuaggcc aagaucuucu caacagcuac     1800

auugaaaaug aggggaagau gaucaugcaa gauaaguuag agaaagaaag aaaugaugcu     1860

aagaaugccg uugaagaaua uguauaugau uuuagagaca ggcugggcac ugucuaugaa     1920

aaauucauca cuccagaaga cuugaguaaa cugucugcag uauuggaaga cacagaaaau     1980

uggcuuuaug aagacggaga ggaccaaccu aaacaaguuu auguggauaa gcugcaagaa     2040

cuaaagaaau acggccagcc uauucaaaug aaguacaugg agcaugaaga gagaccaaaa     2100

gccuuaaaug acuugggaaa aaagauccaa cuugucauga aagugauaga agcauauaga     2160

aacaaggaug aaagauauga ucaucuggau ccuacugaaa uggaaaaggu ugaaaaaugu     2220

aucagugaug ccaugaguug gcugaauagu aagaugaaug cacagaacaa acuaagucuc     2280

acucaagauc cugugguaaa aguuucagaa auaguagcaa agucaaagga acuggauaau     2340

uucuguaacc ccaucauuua caagcccaaa ccaaaagcag aaguuccuga agacaaacca     2400

aaagcuaaua gugaacacaa uggcccaaug gauggacaga guggaacuga aacuaaauca     2460

gauucaacaa aagacagcuc acagcauacu aaauccucug gagagaugga aguggacuaa     2520


<210>  5981
<211>  1965
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_005338.1__HsHSPA5

<400>  5981
augaagcucu cccugguggc cgcgaugcug cugcugcuca gcgcggcgcg ggccgaggag       60

gaggacaaga aggaggacgu gggcacggug gucggcaucg accuggggac caccuacucc      120

ugcgucggcg uguucaagaa cggccgcgug gagaucaucg ccaacgauca gggcaaccgc      180

aucacgccgu ccuaugucgc cuucacuccu gaaggggaac gucugauugg cgaugccgcc      240

aagaaccagc ucaccuccaa ccccgagaac acggucuuug acgccaagcg gcucaucggc      300

cgcacgugga augacccguc ugugcagcag gacaucaagu ucuugccguu caaggugguu      360

gaaaagaaaa cuaaaccaua cauucaaguu gauauuggag gugggcaaac aaagacauuu      420

gcuccugaag aaauuucugc caugguucuc acuaaaauga aagaaaccgc ugaggcuuau      480

uugggaaaga agguuaccca ugcaguuguu acuguaccag ccuauuuuaa ugaugcccaa      540

cgccaagcaa ccaaagacgc uggaacuauu gcuggccuaa auguuaugag gaucaucaac      600

gagccuacgg cagcugcuau ugcuuauggc cuggauaaga gggaggggga gaagaacauc      660

cugguguuug accugggugg cggaaccuuc gaugugucuc uucucaccau ugacaauggu      720

gucuucgaag uuguggccac uaauggagau acucaucugg guggagaaga cuuugaccag      780

cgugucaugg aacacuucau caaacuguac aaaaagaaga cgggcaaaga ugucaggaaa      840

gacaauagag cugugcagaa acuccggcgc gagguagaaa aggccaaacg ggcccugucu      900

ucucagcauc aagcaagaau ugaaauugag uccuucuaug aaggagaaga cuuuucugag      960

acccugacuc gggccaaauu ugaagaacuc aacauggauc uguuccgguc uacuaugaag     1020

cccguccaga aaguguugga agauucugau uugaagaagu cugauauuga ugaaauuguu     1080

cuuguuggug gcucgacucg aaucccaaag auucagcaac ugguuaaaga guucuucaau     1140

ggcaaggaac caucccgugg cauaaaccca gaugaagcug uagcguaugg ugcugcuguc     1200

caggcuggug ugcucucugg ugaucaagau acaggugacc ugguacugcu ugauguaugu     1260

ccccuuacac uugguauuga aacuguggga ggugucauga ccaaacugau uccaaggaac     1320

acaguggugc cuaccaagaa gucucagauc uuuucuacag cuucugauaa ucaaccaacu     1380

guuacaauca aggucuauga aggugaaaga ccccugacaa aagacaauca ucuucugggu     1440

acauuugauc ugacuggaau cccuccugcu ccucgugggg ucccacagau ugaagucacc     1500

uuugagauag augugaaugg uauucuucga gugacagcug aagacaaggg uacagggaac     1560

aaaaauaaga ucacaaucac caaugaccag aaucgccuga caccugaaga aaucgaaagg     1620

augguuaaug augcugagaa guuugcugag gaagacaaaa agcucaagga gcgcauugau     1680

acuagaaaug aguuggaaag cuaugccuau ucucuaaaga aucagauugg agauaaagaa     1740

aagcugggag guaaacuuuc cucugaagau aaggagacca uggaaaaagc uguagaagaa     1800

aagauugaau ggcuggaaag ccaccaagau gcugacauug aagacuucaa agcuaagaag     1860

aaggaacugg aagaaauugu ucaaccaauu aucagcaaac ucuauggaag ugcaggcccu     1920

cccccaacug gugaagagga uacagcagaa aaagaugagu uguag                     1965


<210>  5982
<211>  1932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002146.2__HsHSPA6

<400>  5982
augcaggccc cacgggagcu cgcggugggc aucgaccugg gcaccaccua cucgugcgug       60

ggcguguuuc agcagggccg cguggagauc cuggccaacg accagggcaa ccgcaccacg      120

cccagcuacg uggccuucac cgacaccgag cggcuggucg gggacgcggc caagagccag      180

gcggcccuga acccccacaa caccguguuc gaugccaagc ggcugaucgg gcgcaaguuc      240

gcggacacca cggugcaguc ggacaugaag cacuggcccu uccggguggu gagcgagggc      300

ggcaagccca aggugcgcgu augcuaccgc ggggaggaca agacguucua ccccgaggag      360

aucucgucca uggugcugag caagaugaag gagacggccg aggcguaccu gggccagccc      420

gugaagcacg cagugaucac cgugcccgcc uauuucaaug acucgcagcg ccaggccacc      480

aaggacgcgg gggccaucgc ggggcucaac guguugcgga ucaucaauga gcccacggca      540

gcugccaucg ccuaugggcu ggaccggcgg ggcgcgggag agcgcaacgu gcucauuuuu      600

gaccugggug ggggcaccuu cgaugugucg guucucucca uugacgcugg ugucuuugag      660

gugaaagcca cugcuggaga uacccaccug ggaggagagg acuucgacaa ccggcucgug      720

aaccacuuca uggaagaguu ccggcggaag caugggaagg accugagcgg gaacaagcgu      780

gcccugcgca ggcugcgcac agccugugag cgcgccaagc gcacccuguc cuccagcacc      840

caggccaccc uggagauaga cucccuguuc gagggcgugg acuucuacac guccaucacu      900

cgugcccgcu uugaggaacu gugcucagac cucuuccgca gcacccugga gccgguggag      960

aaggcccugc gggaugccaa gcuggacaag gcccagauuc augacgucgu ccuggugggg     1020

ggcuccacac gcauccccaa ggugcagaag uugcugcagg acuucuucaa cggcaaggag     1080

cugaacaaga gcaucaaccc ugaugaggcu guggccuaug gggcugcugu gcaggcggcc     1140

guguugaugg gggacaaaug ugagaaagug caggaucucc ugcugcugga uguggcuccc     1200

cugucucugg ggcuggagac agcaggaggg gugaugacca cgcugaucca gaggaacgcc     1260

acuaucccca ccaagcagac ccagacuuuc accaccuacu cggacaacca gccugggguc     1320

uucauccagg uguaugaggg ugagagggcc augaccaagg acaacaaccu gcuggggcgu     1380

uuugaacuca guggcauccc uccugcccca cguggagucc cccagauaga ggugacuuuu     1440

gacauugaug cuaauggcau ccugagcgug acagccacug acaggagcac agguaaggcu     1500

aacaagauca ccaucaccaa ugacaagggc cggcugagca aggaggaggu ggagaggaug     1560

guucaugaag ccgagcagua caaggcugag gaugaggccc agagggacag aguggcugcc     1620

aaaaacucgc uggaggccca ugucuuccau gugaaagguu cuuugcaaga ggaaagccuu     1680

agggacaaga uucccgaaga ggacaggcgc aaaaugcaag acaagugucg ggaaguccuu     1740

gccuggcugg agcacaacca gcuggcagag aaggaggagu augagcauca gaagagggag     1800

cuggagcaaa ucugucgccc caucuucucc aggcucuaug gggggccugg ugucccuggg     1860

ggcagcaguu guggcacuca agcccgccag ggggacccca gcaccggccc caucauugag     1920

gagguugauu ga                                                         1932


<210>  5983
<211>  1104
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__P48741__HsHSPA7

<400>  5983
augcaggccc cacgggagcu cgcggugggc aucgaccugg gcaccaccua cucgugcgug       60

ggcguguuuc agcagggccg cguggagauc cuggccaacg accagggcaa ccgcaccacg      120

cccagcuacg uggccuucac cgacaccgag cggcuggucg gggacgcggc caagagccag      180

gcggcccuga acccccacaa caccguguuc gaugccaagc ggcugaucgg gcgcaaguuc      240

gcggacacca cggugcaguc ggacaugaag cacuggcccu uccagguggu gagcgagggc      300

ggcaagccca aggugcgcgu augcuaccgc ggggaggaca agacguucua ccccgaggag      360

aucucgucca uggugcugag caagaugaag gagacggccg aggcguaccu gggccagccc      420

gugaagcacg cagugaucac cgugcccacc uauuucagua acucgcagcg ccaggccacc      480

aaggacgcgg gggccaucgc ggggcucaag gugcugccga ucaucaauga ggccacggca      540

gcagccaucg ccuaugggcu ggaccggcgg ggcgcgggaa agcgcaacgu gcucauuuuu      600

gaccugggug ggggcaccuu cgaugugucg guucucucca uugacgccgg ugucuuugag      660

gugaaagcca cugcuggaga uacccaccug ggaggagagg acuucgacaa ccggcucgug      720

aaccacuuca uggaagaguu ccggcggaag caugggaagg accugagcgg gaacaagcgu      780

gcccugcgca ggcugcgcac agccugugag cgcgccaagc gcaccccguc cuccagcacc      840

caggccaccc uggagauaga cucccuguuc gagggcgugg acuucuacaa guccaucacu      900

cgugcccgcu uugaggaacu gugcucagac cucuuccgca gcacccugga gccgguggag      960

aaggcccugc gggaugccaa gcuggacaag gcccagauuc augacuucgu ccugggggga     1020

gggcuccacu cgcaucccca aggugcagaa guugcugcag gacuucuuca acggcaagga     1080

gcugaacaag agcaucaacc cuga                                            1104


<210>  5984
<211>  1941
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_006588.1 __HsHSPA8

<400>  5984
auguccaagg gaccugcagu ugguauugau cuuggcacca ccuacucuug uguggguguu       60

uuccagcacg gaaaagucga gauaauugcc aaugaucagg gaaaccgaac cacuccaagc      120

uaugucgccu uuacggacac ugaacgguug aucggugaug ccgcaaagaa ucaaguugca      180

augaacccca ccaacacagu uuuugaugcc aaacgucuga uuggacgcag auuugaugau      240

gcuguugucc agucugauau gaaacauugg cccuuuaugg uggugaauga ugcuggcagg      300

cccaaggucc aaguagaaua caagggagag accaagagcu ucuauccaga ggaggugucu      360

ucuaugguuc ugacaaagau gaaggaaauu gcagaagccu accuugggaa gacuguuacc      420

aaugcugugg ucacagugcc agcuuacuuu aaugacucuc agcgucaggc uaccaaagau      480

gcuggaacua uugcuggucu caauguacuu agaauuauua augagccaac ugcugcugcu      540

auugcuuacg gcuuagacaa aaagguugga gcagaaagaa acgugcucau cuuugaccug      600

ggagguggca cuuuugaugu gucaauccuc acuauugagg auggaaucuu ugaggucaag      660

ucuacagcug gagacaccca cuugggugga gaagauuuug acaaccgaau ggucaaccau      720

uuuauugcug aguuuaagcg caagcauaag aaggacauca gugagaacaa gagagcugua      780

agacgccucc guacugcuug ugaacgugcu aagcguaccc ucucuuccag cacccaggcc      840

aguauugaga ucgauucucu cuaugaagga aucgacuucu auaccuccau uacccgugcc      900

cgauuugaag aacugaaugc ugaccuguuc cguggcaccc uggacccagu agagaaagcc      960

cuucgagaug ccaaacuaga caagucacag auucaugaua uuguccuggu uggugguucu     1020

acucguaucc ccaagauuca gaagcugcuc caagacuucu ucaauggaaa agaacugaau     1080

aagagcauca acccugauga agcuguugcu uauggugcag cuguccaggc agccaucuug     1140

ucuggagaca agucugagaa uguucaagau uugcugcucu uggaugucac uccucuuucc     1200

cuugguauug aaacugcugg uggagucaug acuguccuca ucaagcguaa uaccaccauu     1260

ccuaccaagc agacacagac cuucacuacc uauucugaca accagccugg ugugcuuauu     1320

cagguuuaug aaggcgagcg ugccaugaca aaggauaaca accugcuugg caaguuugaa     1380

cucacaggca uaccuccugc accccgaggu guuccucaga uugaagucac uuuugacauu     1440

gaugccaaug guauacucaa ugucucugcu guggacaaga guacgggaaa agagaacaag     1500

auuacuauca cuaaugacaa gggccguuug agcaaggaag acauugaacg uaugguccag     1560

gaagcugaga aguacaaagc ugaagaugag aagcagaggg acaagguguc auccaagaac     1620

ucacuugagu ccuaugccuu caacaugaaa gcaacuguug aagaugagaa acuucaaggc     1680

aagauuaacg augaggacaa acagaagauu cuggacaagu guaaugaaau uaucaacugg     1740

cuugauaaga aucagacugc ugagaaggaa gaauuugaac aucaacagaa agagcuggag     1800

aaaguuugca accccaucau caccaagcug uaccagagug caggaggcau gccaggagga     1860

augccugggg gauuuccugg ugguggagcu ccucccucug guggugcuuc cucagggccc     1920

accauugaag agguugauua a                                               1941


<210>  5985
<211>  2040
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_004125.3 __HsHSPA9

<400>  5985
augauaagug ccagccgagc ugcagcagcc cgucucgugg gcgccgcagc cucccggggc       60

ccuacggccg cccgccacca ggauagcugg aauggccuua gucaugaggc uuuuagacuu      120

guuucaaggc gggauuaugc aucagaagca aucaagggag caguuguugg uauugauuug      180

gguacuacca acuccugcgu ggcaguuaug gaagguaaac aagcaaaggu gcuggagaau      240

gccgaaggug ccagaaccac cccuucaguu guggccuuua cagcagaugg ugagcgacuu      300

guuggaaugc cggccaagcg acaggcuguc accaacccaa acaauacauu uuaugcuacc      360

aagcgucuca uuggccggcg auaugaugau ccugaaguac agaaagacau uaaaaauguu      420

cccuuuaaaa uuguccgugc cuccaauggu gaugccuggg uugaggcuca ugggaaauug      480

uauucuccga gucagauugg agcauuugug uugaugaaga ugaaagagac ugcagaaaau      540

uacuuggggc acacagcaaa aaaugcugug aucacagucc cagcuuauuu caaugacucg      600

cagagacagg ccacuaaaga ugcuggccag auaucuggac ugaaugugcu ucgggugauu      660

aaugagccca cagcugcugc ucuugccuau ggucuagaca aaucagaaga caaagucauu      720

gcuguauaug auuuaggugg uggaacuuuu gauauuucua uccuggaaau ucagaaagga      780

guauuugagg ugaaauccac aaauggggau accuucuuag guggggaaga cuuugaccag      840

gccuugcuac ggcacauugu gaaggaguuc aagagagaga cagggguuga uuugacuaaa      900

gacaacaugg cacuucagag gguacgggaa gcugcugaaa aggcuaaaug ugaacucucc      960

ucaucugugc agacugacau caauuugccc uaucuuacaa uggauucuuc uggacccaag     1020

cauuugaaua ugaaguugac ccgugcucaa uuugaaggga uugucacuga ucuaaucaga     1080

aggacuaucg cuccaugcca aaaagcuaug caagaugcag aagucagcaa gagugacaua     1140

ggagaaguga uucuuguggg uggcaugacu aggaugccca agguucagca gacuguacag     1200

gaucuuuuug gcagagcccc aaguaaagcu gucaauccug augaggcugu ggccauugga     1260

gcugccauuc agggaggugu guuggccggc gaugucacgg augugcugcu ccuugauguc     1320

acuccccugu cucuggguau ugaaacucua ggaggugucu uuaccaaacu uauuaauagg     1380

aauaccacua uuccaaccaa gaaaagccag guauucucua cugccgcuga uggucaaacg     1440

caaguggaaa uuaaagugug ucagggugaa agagagaugg cuggagacaa caaacuccuu     1500

ggacaguuua cuuugauugg aaucccacca gccccucgug gaguuccuca gauugaaguu     1560

acauuugaca uugaugccaa ugggauagua cauguuucug cuaaagauaa aggcacagga     1620

cgugagcagc agauuguaau ccagucuucu gguggauuaa gcaaagauga uauugaaaau     1680

augguuaaaa augcagagaa auaugcugaa gaagaccggc gaaagaagga acgaguugaa     1740

gcaguuaaua uggcugaagg aaucauucac gacacagaaa ccaagaugga agaguucaag     1800

gaccaauuac cugcugauga gugcaacaag cugaaagaag agauuuccaa aaugagggag     1860

cuccuggcua gaaaagacag cgaaacagga gaaaauauua gacaggcagc auccucucuu     1920

cagcaggcau cacugaagcu guucgaaaug gcauacaaaa agauggcauc ugagcgagaa     1980

ggcucuggaa guucuggcac uggggaacaa aaggaagauc aaaaggagga aaaacaguaa     2040


<210>  5986
<211>  2061
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_443202.3 __HsHSPA12B

<400>  5986
auguuggcug ucccggagau gggccugcag gggcuguaca ucggcuccag cccggagcgg       60

uccccagugc cuagcccacc cggcuccccg aggacccagg aaagcugcgg cauugccccc      120

cucacacccu cgcagucucc aaaacccgag guccgagccc cccagcaggc cuccuucucu      180

gugguggugg ccauugacuu cggcaccacg ucuaguggcu augcuuucag cuuugccagu      240

gacccugagg ccauccacau gaugaggaaa ugggagggcg gagacccggg cguggcccac      300

cagaagaccc cgaccugccu gcugcugacu ccggagggcg ccuuccacag cuuuggcuac      360

accgcccgcg auuacuacca ugaccuggac cccgaagagg cgcgggacug gcucuacuuc      420

gagaaguuca agaugaagau ccacagcgcc acggaucuca ccuugaagac ccagcuagag      480

gcaguaaaug gaaagacgau gcccgcccug gagguguucg cccaugcccu gcgcuucuuc      540

agggagcacg cccuucagga gcugagggag cagagcccau cgcugccaga gaaggacacu      600

gugcgcuggg uguugacggu gccugccauc uggaaacagc cagccaagca guucaugcgg      660

gaggcugccu accuggcugg acuugugucc cgagagaaug cagagcagcu acucaucgcc      720

cuggagcccg aggccgccuc gguauacugc cgcaagcugc gccugcacca gcuccuggac      780

cugaguggcc gggccccagg uggugggcgc cugggugagc gccgcuccau cgacuccagc      840

uuccgucagg cucgggagca gcugcgaagg ucccgccaca gccgcacguu ccugguggag      900

ucaggcguag gagagcugug ggcagagaug caagcaggag accgcuacgu gguggccgac      960

ugcggcggag gcaccgugga ccugacggug caccagcugg agcagcccca uggcacccuc     1020

aaggagcucu acaaggcauc ugggggcccu uauggcgcgg ugggcgugga ccuggccuuc     1080

gagcagcugc ugugccgcau cuucggcgag gacuucaucg ccaccuucaa aaggcaacgg     1140

ccggcagccu ggguagaucu gaccaucgcc uucgaggcuc gcaagcgcac ugcuggccca     1200

caccgugcag gggcgcucaa caucucgcug cccuucuccu ucauugacuu cuaccgcaag     1260

cagcggggcc acaacgugga gaccgcucug cgcaggagca gcgugaacuu cgugaagugg     1320

uccucacagg ggaugcuccg aaugucuugu gaagccauga acgagcucuu ucagcccacc     1380

gucagcggga ucauccagca cauagaggcc cugcuggcac ggccggaggu gcagggugug     1440

aagcugcugu uccuaguggg cggcuucgcc gagucagcgg ugcugcagca cgcggugcag     1500

gcggcgcugg gcgcccgcgg ucugcguguc guggucccgc acgacguggg ccucaccauc     1560

cucaaaggcg cggugcuguu cggccaggcg ccgggcgugg ugcggguccg ccgcucgccg     1620

cucaccuaug gcgugggcgu gcucaaccgc uuugugccug ggcgccaccc gcccgaaaag     1680

cugcugguuc gcgacggccg ccgcuggugc accgacgucu ucgagcgcuu cguggccgcc     1740

gagcagucgg uggcccuggg cgaggaggug cggcgcagcu acugcccggc gcgucccggc     1800

cagcggcgcg uacucaucaa ccuguacugc ugcgcggcag aggaugcgcg cuucaucacc     1860

gaccccggcg ugcgcaaaug cggcgcgcuc agccucgagc uugagcccgc cgacugcggc     1920

caggacaccg ccggcgcgcc ucccggccgc cgcgagaucc gcgccgccau gcaguuuggc     1980

gacaccgaaa uuaaggucac cgccgucgac gucagcacca aucgcuccgu gcgcgcgucc     2040

aucgacuuuc uuuccaacug a                                               2061


<210>  5987
<211>  1530
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_057383.2__HsHSPA14

<400>  5987
auggcggcca ucggaguuca ccugggcugc accucagccu guguggccgu cuauaaggau       60

ggccgggcug gugugguugc aaaugaugcc ggugaccgag uuacuccagc uguuguugcu      120

uacucagaaa augaagagau uguuggauug gcagcaaaac aaaguagaau aagaaauauu      180

ucaaauacag uaaugaaagu aaagcagauc cugggcagaa gcuccaguga uccacaagcu      240

cagaaauaca ucgcggaaag uaaauguuua gucauugaaa aaaaugggaa auuacgauau      300

gaaauagaua cuggagaaga aacaaaauuu guuaacccag aagauguugc cagacugaua      360

uuuaguaaaa ugaaagaaac ggcacauucu guauugggcu cagaugcaaa ugauguaguu      420

auuacugucc cguuugauuu uggagaaaag caaaaaaaug cucuuggaga agcagcuaga      480

gcugcuggau uuaauguuuu gcgauuaauu cacgaaccgu cugcagcucu gcuugcuuau      540

ggaauuggac aagacucccc uacuggaaaa agcaauauuu ugguguuuaa gcugggagga      600

acauccuuau cucucagcgu cauggaaguu aacaguggaa uauaucgggu ucuuucaaca      660

aacacugaug auaacaucgg uggugcacau uucacagaaa ccuuagcaca guaucuagcu      720

ucugaguucc aaagauccuu caaacaugau gugagaggaa augcgcgagc caugaugaaa      780

uuaacgaaca gugcugaagu agcgaaacau ucuuugucaa ccuugggaag ugccaacugu      840

uuucuugacu cauuauauga aggucaagau uuugauugca auguguccag agcaagauuu      900

gaacuucuuu guucuccacu uuuuaauaag uguauagaag caaucagagg acucuuagau      960

caaaauggau uuacagcaga ugauaucaac aagguugucc uuuguggagg gucuucucga     1020

aucccaaagc uacagcaacu gauuaaagau cuuuucccag cuguugagcu ucucaauucu     1080

aucccuccug augaagugau cccuauuggu gcagcuauag aagcaggaau ccuuauuggg     1140

aaagaaaacc uguuggugga agacucucuu augauagagu guucagccag agauauuuua     1200

guuaagggug uggacgaauc aggagccagu agauucacag ugcuguuucc aucagggacu     1260

ccuuugccag cucgaagaca acacacauug caagccccug gaagcauauc uucagugugc     1320

cuugaacucu augagucuga ugggaagaac ucugccaaag aggaaaccaa guuugcacag     1380

guuguacucc aggauuuaga uaaaaaagaa aauggauuac gugauauauu agcuguucuu     1440

acuaugaaaa gggauggauc uuuacaugug acaugcacag aucaagaaac uggaaaaugu     1500

gaagcaaucu cuauugagau agcaucuuag                                      1530


<210>  5988
<211>  2577
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_006635.2 __HsHSPH1

<400>  5988
augucggugg ugggguugga cgugggcucg cagagcugcu acaucgcggu agcccgggcc       60

gggggcaucg agaccaucgc caaugaguuc agcgaccggu gcaccccguc agucauauca      120

uuuggaucaa aaaauagaac aaucggaguu gcagccaaaa aucagcaaau cacucaugca      180

aacaauacgg ugucuaacuu caaaagauuu cauggccgag cauucaauga ccccuucauu      240

caaaaggaga aggaaaacuu gaguuacgau uugguuccau ugaaaaaugg uggaguugga      300

auaaagguaa uguacauggg ugaagaacau cuauuuagug uggagcagau aacagccaug      360

uuguugacua agcugaagga aacugcugaa aacagccuca agaaaccagu aacagauugu      420

guuauuucag uccccuccuu cuuuacagau gcugagaggc gaucuguguu agaugcugca      480

cagauuguug gccuaaacug uuuaagacuu augaaugaca ugacagcugu ugcuuugaau      540

uacggaauuu auaagcagga ucucccaagc cuggaugaga aaccucggau agugguuuuu      600

guugauaugg gacauucagc uuuucaagug ucugcuugug cuuuuaacaa gggaaaauug      660

aagguacugg gaacagcuuu ugauccuuuc uuaggaggaa aaaacuucga ugaaaaguua      720

guggaacauu uuugugcaga auuuaaaacu aaguacaagu uggaugcaaa auccaaaaua      780

cgagcacucc uacgucugua ucaggaaugu gaaaaacuga aaaagcuaau gagcucuaac      840

agcacagacc uuccacugaa uaucgaaugc uuuaugaaug auaaagaugu uuccggaaag      900

augaacaggu cacaauuuga agaacucugu gcugaacuuc ugcaaaagau agaaguaccc      960

cuuuauucac uguuggaaca aacucaucuc aaaguagaag augugagugc aguugagauu     1020

guuggaggcg cuacacgaau cccagcugug aaggaaagaa uugccaaauu cuuuggaaaa     1080

gauauuagca caacacucaa ugcagaugaa gcaguagcca gaggaugugc auuacagugu     1140

gcaauacuuu ccccggcauu uaaaguuaga gaauuuuccg ucacagaugc aguuccuuuu     1200

ccaauaucuc ugaucuggaa ccaugauuca gaagauacug aagguguuca ugaagucuuu     1260

agucgaaacc augcugcucc uuucuccaaa guucucaccu uucugagaag ggggccuuuu     1320

gagcuagaag cauucuauuc ugauccccaa ggaguuccau auccagaagc aaaaauaggc     1380

cgcuuuguag uucagaaugu uucugcacag aaagauggag aaaaaucuag aguaaaaguc     1440

aaagugcgag ucaacaccca uggcauuuuc accaucucua cggcaucuau gguggagaaa     1500

gucccaacug aggagaauga aaugucuucu gaagcugaca uggagugucu gaaucagaga     1560

ccaccagaaa acccagacac ugauaaaaau guccagcaag acaacaguga agcuggaaca     1620

cagccccagg uacaaacuga ugcucaacaa accucacagu cucccccuuc accugaacuu     1680

accucagaag aaaacaaaau cccagaugcu gacaaagcaa augaaaaaaa aguugaccag     1740

ccuccagaag cuaaaaagcc caaaauaaag guggugaaug uugagcugcc uauugaagcc     1800

aacuuggucu ggcaguuagg gaaagaccuu cuuaacaugu auauugagac agaggguaag     1860

augauaaugc aagauaaauu ggaaaaagaa aggaaugaug cuaaaaaugc aguugaggaa     1920

uauguguaug aguucagaga caagcugugu ggaccauaug aaaaauuuau augugagcag     1980

gaucaucaaa auuuuuugag acuccucaca gaaacugaag acuggcugua ugaagaagga     2040

gaggaccaag cuaaacaagc auauguugac aaguuggaag aauuaaugaa aauuggcacu     2100

ccaguuaaag uucgguuuca ggaagcugaa gaacggccaa aaauguuuga agaacuagga     2160

cagaggcugc agcauuaugc caagauagca gcugacuuca gaaauaagga ugagaaauac     2220

aaccauauug augagucuga aaugaaaaaa guggagaagu cuguuaauga agugauggaa     2280

uggaugaaua augucaugaa ugcucaggcu aaaaagaguc uugaucagga uccaguugua     2340

cgugcucagg aaauuaaaac aaaaaucaag gaauugaaca acacauguga acccguugua     2400

acacaaccga aaccaaaaau ugaaucaccc aaacuggaaa gaacuccaaa uggcccaaau     2460

auugauaaaa aggaagaaga uuuagaagac aaaaacaauu uuggugcuga accuccacau     2520

cagaauggug aauguuaccc uaaugagaaa aauucuguua auauggacuu ggacuag        2577


<210>  5989
<211>  3000
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_006380.1 __HsHYOU1

<400>  5989
auggcagaca aaguuaggag gcagaggccg aggaggcgag ucuguugggc cuugguggcu       60

gugcucuugg cagaccuguu ggcacugagu gauacacugg cagugauguc uguggaccug      120

ggcagugagu ccaugaaggu ggccauuguc aaaccuggag ugcccaugga aauugucuug      180

aauaaggaau cucggaggaa aacaccggug aucgugaccc ugaaagaaaa ugaaagauuc      240

uuuggagaca gugcagcaag cauggcgauu aagaauccaa aggcuacgcu acguuacuuc      300

cagcaccucc uggggaagca ggcagauaac ccccauguag cucuuuacca ggcccgcuuc      360

ccggagcacg agcugacuuu cgacccacag aggcagacug ugcacuuuca gaucagcucg      420

cagcugcagu ucucaccuga ggaaguguug ggcaugguuc ucaauuauuc ucguucucua      480

gcugaagauu uugcagagca gcccaucaag gaugcaguga ucaccgugcc agucuucuuc      540

aaccaggccg agcgccgagc ugugcugcag gcugcucgua uggcuggccu caaagugcug      600

cagcucauca augacaacac cgccacugcc cucagcuaug gugucuuccg ccggaaagau      660

auuaacacca cugcccagaa uaucauguuc uaugacaugg gcucaggcag caccguaugc      720

accauuguga ccuaccagau ggugaagacu aaggaagcug ggaugcagcc acagcugcag      780

auccggggag uaggauuuga ccguacccug gggggccugg agauggagcu ccggcuucga      840

gaacgccugg cugggcuuuu caaugagcag cgcaaggguc agagagcaaa ggaugugcgg      900

gagaacccgc gugccauggc caagcugcug cgugaggcua aucggcucaa aaccguccuc      960

agugccaacg cugaccacau ggcacagauu gaaggccuga uggaugaugu ggacuucaag     1020

gcaaaaguga cucgugugga auuugaggag uugugugcag acuuguuuga gcgggugccu     1080

gggccuguac agcaggcccu ccagagugcc gaaaugaguc uggaugagau ugagcagguc     1140

auccuggugg guggggccac ucgggucccc agaguucagg aggugcugcu gaaggccgug     1200

ggcaaggagg agcuggggaa gaacaucaau gcagaugaag cagccgccau gggggcagug     1260

uaccaggcag cugcgcucag caaagccuuu aaagugaagc cauuugucgu ccgagaugca     1320

guggucuacc ccauccuggu ggaguucacg agggaggugg aggaggagcc ugggauucac     1380

agccugaagc acaauaaacg gguacucuuc ucucggaugg ggcccuaccc ucaacgcaaa     1440

gucaucaccu uuaaccgcua cagccaugau uucaacuucc acaucaacua cggcgaccug     1500

ggcuuccugg ggccugaaga ucuucgggua uuuggcuccc agaaucugac cacagugaag     1560

cuaaaagggg ugggugacag cuucaagaag uauccugacu acgaguccaa gggcaucaag     1620

gcucacuuca accuggauga gaguggcgug cucagucuag acagggugga gucuguauuu     1680

gagacacugg uagaggacag cgcagaagag gaaucuacuc ucaccaaacu uggcaacacc     1740

auuuccagcc uguuuggagg cgguaccaca ccagaugcca aggagaaugg uacugauacu     1800

guccaggagg aagaggagag cccugcagag gggagcaagg acgagccugg ggagcagguc     1860

gagcucaagg aggaagcuga ggccccagug gaggauggcu cucagccccc acccccugaa     1920

ccuaagggag augcaacccc ugagggagaa aaggccacag aaaaagaaaa uggggacaag     1980

ucugaggccc agaaaccaag ugagaaggca gaggcagggc cugagggcgu cgcuccagcc     2040

ccagagggag agaagaagca gaagcccgcc aggaagcggc gaaugguaga ggagaucggg     2100

guggagcugg uuguucugga ccugccugac uugccagagg auaagcuggc ucagucggug     2160

cagaaacuuc aggacuugac acuccgagac cuggagaagc aggaacggga aaaagcugcc     2220

aacagcuugg aagcauucau auuugagacc caggacaagc uguaccagcc cgaguaccag     2280

gaagugucca cagaggagca gcgugaggag aucucuggga agcucagcgc cgcauccacc     2340

uggcuggagg augagggugu uggagccacc acagugaugu ugaaggagaa gcuggcugag     2400

cugaggaagc ugugccaagg gcuguuuuuu cggguagagg agcgcaagaa guggcccgaa     2460

cggcugucug cccucgauaa ucuccucaac cauuccagca uguuccucaa gggggcccgg     2520

cucaucccag agauggacca gaucuucacu gagguggaga ugacaacguu agagaaaguc     2580

aucaaugaga ccugggccug gaagaaugca acucuggccg agcaggcuaa gcugcccgcc     2640

acagagaagc cuguguugcu cucaaaagac auugaagcua agaugauggc ccuggaccga     2700

gaggugcagu aucugcucaa uaaggccaag uuuaccaagc cccggccccg gccuaaggac     2760

aagaauggga cccgggcaga gccaccccuc aaugccagug ccagugacca gggggagaag     2820

gucaucccuc cagcaggcca gacugaagau gcagagccca uuucagaacc ugagaaagua     2880

gagacuggau ccgagccagg agacacugag ccuuuggagu uaggaggucc uggagcagaa     2940

ccugaacaga aagaacaauc gacaggacag aagcggccuu ugaagaacga cgaacuauaa     3000


<210>  5990
<211>  2199
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_005339.3 __HsHSP90AA1

<400>  5990
augccugagg aaacccagac ccaagaccaa ccgauggagg aggaggaggu ugagacguuc       60

gccuuucagg cagaaauugc ccaguugaug ucauugauca ucaauacuuu cuacucgaac      120

aaagagaucu uucugagaga gcucauuuca aauucaucag augcauugga caaaauccgg      180

uaugagagcu ugacagaucc caguaaauua gacucuggga aagagcugca uauuaaccuu      240

auaccgaaca aacaagaucg aacucucacu auuguggaua cuggaauugg aaugaccaag      300

gcugacuuga ucaauaaccu ugguacuauc gccaagucug ggaccaaagc guucauggaa      360

gcauugcagg cuggugcaga uaucucuaug auuggccagu ucgguguugg uuuuuauucu      420

gcuuauuugg uugcugagaa aguaacugug aucaccaaac auaacgauga ugagcaguac      480

gcuugggagu ccucagcagg gggaucauuc acagugagga cagacacagg ugaaccuaug      540

ggucguggaa caaaaguuau ccuacaccug aaagaagacc aaacugagua cuuggaggaa      600

cgaagaauaa aggagauugu gaagaaacau ucucaguuua uuggauaucc cauuacucuu      660

uuuguggaga aggaacguga uaaagaagua agcgaugaug aggcugaaga aaaggaagac      720

aaagaagaag aaaaagaaaa agaagagaaa gagucggaag acaaaccuga aauugaagau      780

guugguucug augaggaaga agaaaagaag gauggugaca agaagaagaa gaagaagauu      840

aaggaaaagu acaucgauca agaagaacuc aacaaaacaa agcccaucug gaccagaaau      900

cccgacgaua uuacuaauga ggaguacgga gaguucuaua agagcuugac caaugacugg      960

gaagaucacu uggcagugaa gcauuuuuca guugaaggac aguuggaguu cagagcccuu     1020

cuauuugucc cacgacgugc uccuuuugau cuguuugaaa acagaaagaa aaagaacaac     1080

aucaaauugu auguacgcag aguuuucauc auggauaacu gugaggagcu aaucccugaa     1140

uaucugaacu ucauuagagg ggugguagac ucggaggauc ucccucuaaa cauaucccgu     1200

gagauguugc aacaaagcaa aauuuugaaa guuaucagga agaauuuggu caaaaaaugc     1260

uuagaacucu uuacugaacu ggcggaagau aaagagaacu acaagaaauu cuaugagcag     1320

uucucuaaaa acauaaagcu cggaauacac gaagacucuc aaaaucggaa gaagcucuca     1380

gagcuguuaa gguacuacac aucugccucu ggugaugaga ugguuucucu caaggacuac     1440

ugcaccagaa ugaaggagaa ccagaaacau aucuauuaua ucacagguga gaccaaggac     1500

cagguagcua acucagccuu uguggaacgu cuucggaaac auggcuuaga agugaucuau     1560

augauugagc ccauugauga guacuguguc caacagcuga aggaauuuga ggggaagacu     1620

uuagugucag ucaccaaaga aggccuggaa cuuccagagg augaagaaga gaaaaagaag     1680

caggaagaga aaaaaacaaa guuugagaac cucugcaaaa ucaugaaaga cauauuggag     1740

aaaaaaguug aaaagguggu ugugucaaac cgauugguga caucuccaug cuguauuguc     1800

acaagcacau auggcuggac agcaaacaug gagagaauca ugaaagcuca agcccuaaga     1860

gacaacucaa caauggguua cauggcagca aagaaacacc uggagauaaa cccugaccau     1920

uccauuauug agaccuuaag gcaaaaggca gaggcugaua agaacgacaa gucugugaag     1980

gaucugguca ucuugcuuua ugaaacugcg cuccugucuu cuggcuucag ucuggaagau     2040

ccccagacac augcuaacag gaucuacagg augaucaaac uuggucuggg uauugaugaa     2100

gaugacccua cugcugauga uaccagugcu gcuguaacug aagaaaugcc accccuugaa     2160

ggagaugacg acacaucacg cauggaagaa guagacuaa                            2199


<210>  5991
<211>  339
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NG_005218__HsHSP90AA3P

<400>  5991
auggauucca guaaauuaga cucugggaaa gggcugcaua uuaaccuugu accaaacaaa       60

caaaaucaaa cccucacuau uguggacacu agaauuggaa ugaccaagac ugacuugauc      120

aauaaccucg guacugucac caagucuggg accaaagcau ucauggaagc auugcaggcu      180

gaugcagaua ucucuaugau uggccauuuc gggguugguu uuuauucugc uuauuugguu      240

gccaagaaag uaacugugau cagcaaacau aacaaugaug agcaguacac cugggagucc      300

ucagcagggg gaucauucac agugaggaca gacgaguga                             339


<210>  5992
<211>  2175
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_031381.2__HsHSP90AB1

<400>  5992
augccugagg aagugcacca uggagaggag gagguggaga cuuuugccuu ucaggcagaa       60

auugcccaac ucaugucccu caucaucaau accuucuauu ccaacaagga gauuuuccuu      120

cgggaguuga ucucuaaugc uucugaugcc uuggacaaga uucgcuauga gagccugaca      180

gacccuucga aguuggacag ugguaaagag cugaaaauug acaucauccc caacccucag      240

gaacguaccc ugacuuuggu agacacaggc auuggcauga ccaaagcuga ucucauaaau      300

aauuugggaa ccauugccaa gucugguacu aaagcauuca uggaggcucu gcaggcuggu      360

gcagacaucu ccaugauugg gcaguuuggu guuggcuuuu auucugccua cuugguggca      420

gagaaagugg uugugaucac aaagcacaac gaugaugaac aguaugcuug ggagucuucu      480

gcuggagguu ccuucacugu gcgugcugac cauggugagc ccauuggcag ggguaccaaa      540

gugauccucc aucuuaaaga agaucagaca gaguaccuag aagagaggcg ggucaaagaa      600

guagugaaga agcauucuca guucauaggc uaucccauca cccuuuauuu ggagaaggaa      660

cgagagaagg aaauuaguga ugaugaggca gaggaagaga aaggugagaa agaagaggaa      720

gauaaagaug augaagaaaa acccaagauc gaagaugugg guucagauga ggaggaugac      780

agcgguaagg auaagaagaa gaaaacuaag aagaucaaag agaaauacau ugaucaggaa      840

gaacuaaaca agaccaagcc uauuuggacc agaaacccug augacaucac ccaagaggag      900

uauggagagu ucuacaagag ccucacuaau gacugggaag accacuuggc agucaagcac      960

uuuucuguag aaggucaguu ggaguucagg gcauugcuau uuauuccucg ucgggcuccc     1020

uuugaccuuu uugagaacaa gaagaaaaag aacaacauca aacucuaugu ccgccgugug     1080

uucaucaugg acagcuguga ugaguugaua ccagaguauc ucaauuuuau ccguggugug     1140

guugacucug aggaucugcc ccugaacauc ucccgagaaa ugcuccagca gagcaaaauc     1200

uugaaaguca uucgcaaaaa cauuguuaag aagugccuug agcuguucuc ugagcuggca     1260

gaagacaagg agaauuacaa gaaauucuau gaggcauucu cuaaaaaucu caagcucgga     1320

auccacgaag acuccacuaa ccgccgccgc cugucugagc ugcugcgcua ucauaccucc     1380

cagucuggag augagaugac aucucuguca gaguauguuu cucgcaugaa ggagacacag     1440

aaguccaucu auuacaucac uggugagagc aaagagcagg ucgccaacuc agcuuuugug     1500

gagcgagugc ggaaacgggg cuucgaggug guauauauga ccgagcccau ugacgaguac     1560

ugugugcagc agcucaagga auuugauggg aaaagccugg ucucaguuac caaggagggu     1620

cuggagcugc cugaggauga ggaggagaag aagaagaugg aagagagcaa ggcaaaguuu     1680

gagaaccucu gcaagcucau gaaagaaauc uuagauaaga agguugagaa ggugacaauc     1740

uccaauagac uugugucuuc accuugcugc auugugacca gcaccuacgg cuggacagcc     1800

aauauggagc ggaucaugaa agcccaggca cuucgggaca acuccaccau gggcuauaug     1860

auggccaaaa agcaccugga gaucaacccu gaccacccca uuguggagac gcugcggcag     1920

aaggcugagg ccgacaagaa ugauaaggca guuaaggacc ugguggugcu gcuguuugaa     1980

accgcccugc uaucuucugg cuuuucccuu gaggaucccc agacccacuc caaccgcauc     2040

uaucgcauga ucaagcuagg ucuagguauu gaugaagaug aaguggcagc agaggaaccc     2100

aaugcugcag uuccugauga gauccccccu cucgagggcg augaggaugc gucucgcaug     2160

gaagaagucg auuag                                                      2175


<210>  5993
<211>  2412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_003290.1__HsHSP90B1

<400>  5993
augagggccc ugugggugcu gggccucugc ugcguccugc ugaccuucgg gucggucaga       60

gcugacgaug aaguugaugu ggaugguaca guagaagagg aucuggguaa aaguagagaa      120

ggaucaagga cggaugauga aguaguacag agagaggaag aagcuauuca guuggaugga      180

uuaaaugcau cacaaauaag agaacuuaga gagaagucgg aaaaguuugc cuuccaagcc      240

gaaguuaaca gaaugaugaa acuuaucauc aauucauugu auaaaaauaa agagauuuuc      300

cugagagaac ugauuucaaa ugcuucugau gcuuuagaua agauaaggcu aauaucacug      360

acugaugaaa augcucuuuc uggaaaugag gaacuaacag ucaaaauuaa gugugauaag      420

gagaagaacc ugcugcaugu cacagacacc gguguaggaa ugaccagaga agaguugguu      480

aaaaaccuug guaccauagc caaaucuggg acaagcgagu uuuuaaacaa aaugacugaa      540

gcacaggaag auggccaguc aacuucugaa uugauuggcc aguuuggugu cgguuucuau      600

uccgccuucc uuguagcaga uaagguuauu gucacuucaa aacacaacaa cgauacccag      660

cacaucuggg agucugacuc caaugaauuu ucuguaauug cugacccaag aggaaacacu      720

cuaggacggg gaacgacaau uacccuuguc uuaaaagaag aagcaucuga uuaccuugaa      780

uuggauacaa uuaaaaaucu cgucaaaaaa uauucacagu ucauaaacuu uccuauuuau      840

guauggagca gcaagacuga aacuguugag gagcccaugg aggaagaaga agcagccaaa      900

gaagagaaag aagaaucuga ugaugaagcu gcaguagagg aagaagaaga agaaaagaaa      960

ccaaagacua aaaaaguuga aaaaacuguc ugggacuggg aacuuaugaa ugauaucaaa     1020

ccaauauggc agagaccauc aaaagaagua gaagaagaug aauacaaagc auucuacaaa     1080

ucauuuucaa aggaaaguga ugaccccaug gcuuauauuc acuuuacugc ugaaggggaa     1140

guuaccuuca aaucaauuuu auuuguaccc acaucugcuc cacguggucu guuugacgaa     1200

uauggaucua aaaagagcga uuacauuaag cucuaugugc gccguguauu caucacagac     1260

gacuuccaug auaugaugcc uaaauaccuc aauuuuguca aggguguggu ggacucagau     1320

gaucuccccu ugaauguuuc ccgcgagacu cuucagcaac auaaacugcu uaaggugauu     1380

aggaagaagc ugguucguaa aacgcuggac augaucaaga agauugcuga ugauaaauac     1440

aaugauacuu uuuggaaaga auuugguacc aacaucaagc ugggugugau ugaagaccac     1500

ucgaaucgaa cacgucuugc uaaacuucuu agguuccagu cuucucauca uccaacugac     1560

auuacuagcc uagaccagua uguggaaaga augaaggaaa aacaagacaa aaucuacuuc     1620

auggcugggu ccagcagaaa agaggcugaa ucuucuccau uuguugagcg acuucugaaa     1680

aagggcuaug aaguuauuua ccucacagaa ccuguggaug aauacuguau ucaggcccuu     1740

cccgaauuug augggaagag guuccagaau guugccaagg aaggagugaa guucgaugaa     1800

agugagaaaa cuaaggagag ucgugaagca guugagaaag aauuugagcc ucugcugaau     1860

uggaugaaag auaaagcccu uaaggacaag auugaaaagg cugugguguc ucagcgccug     1920

acagaaucuc cgugugcuuu gguggccagc caguacggau ggucuggcaa cauggagaga     1980

aucaugaaag cacaagcgua ccaaacgggc aaggacaucu cuacaaauua cuaugcgagu     2040

cagaagaaaa cauuugaaau uaaucccaga cacccgcuga ucagagacau gcuucgacga     2100

auuaaggaag augaagauga uaaaacaguu uuggaucuug cugugguuuu guuugaaaca     2160

gcaacgcuuc ggucagggua ucuuuuacca gacacuaaag cauauggaga uagaauagaa     2220

agaaugcuuc gccucaguuu gaacauugac ccugaugcaa agguggaaga agaacccgaa     2280

gaagaaccug aagagacagc agaagacaca acagaagaca cagagcaaga cgaagaugaa     2340

gaaauggaug ugggaacaga ugaagaagaa gaaacagcaa aggaaucuac agcugaaaaa     2400

gaugaauugu aa                                                         2412


<210>  5994
<211>  2115
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_057376.2__HsTRAP1

<400>  5994
auggcgcgcg agcugcgggc gcugcugcug uggggccgcc gccugcggcc uuugcugcgg       60

gcgccggcgc uggcggccgu gccgggagga aaaccaauuc uguguccucg gaggaccaca      120

gcccaguugg gccccaggcg aaacccagcc uggagcuugc aggcaggacg acuguucagc      180

acgcagaccg ccgaggacaa ggaggaaccc cugcacucga uuaucagcag cacagagagc      240

gugcaggguu ccacuuccaa acaugaguuc caggccgaga caaagaagcu guuggacauu      300

guugcccggu cccuguacuc agaaaaagag guguuuauac gggagcugau cuccaaugcc      360

agcgaugccu uggaaaaacu gcgucacaaa cuggugucug acggccaagc acugccagaa      420

auggagauuc acuugcagac caaugccgag aaaggcacca ucaccaucca ggauacuggu      480

aucgggauga cacaggaaga acuggugucc aaccugggga cgauugccag aucgggguca      540

aaggccuucc uggaugcucu gcagaaccag gcugaggcca gcagcaagau caucggccag      600

uuuggagugg guuucuacuc agcuuucaug guggcugaca gaguggaggu cuauucccgc      660

ucggcagccc cggggagccu ggguuaccag uggcuuucag augguucugg aguguuugaa      720

aucgccgaag caucgggagu uagaaccggg acaaaaauca ucauccaccu gaaauccgac      780

ugcaaggagu uuuccagcga ggcccgggug cgagaugugg uaacgaagua cagcaacuuc      840

gucagcuucc ccuuguacuu gaauggaagg cggaugaaca ccuugcaggc caucuggaug      900

auggacccca aggauguccg ugaguggcaa caugaggagu ucuaccgcua cgucgcgcag      960

gcucacgaca agccccgcua cacccugcac uauaagacgg acgcaccgcu caacauccgc     1020

agcaucuucu acgugcccga caugaaaccg uccauguuug augugagccg ggagcugggc     1080

uccagcguug cacuguacag ccgcaaaguc cucauccaga ccaaggccac ggacauccug     1140

cccaaguggc ugcgcuucau ccgaggugug guggacagug aggacauucc ccugaaccuc     1200

agccgggagc ugcugcagga gagcgcacuc aucaggaaac uccgggacgu uuuacagcag     1260

aggcugauca aauucuucau ugaccagagu aaaaaagaug cugagaagua ugcaaaguuu     1320

uuugaagauu acggccuguu caugcgggag ggcauuguga ccgccaccga gcaggagguc     1380

aaggaggaca uagcaaagcu gcugcgcuac gaguccucgg cgcugcccuc cgggcagcua     1440

accagccucu cagaauacgc cagccgcaug cgggccggca cccgcaacau cuacuaccug     1500

ugcgccccca accgucaccu ggcagagcac ucacccuacu augaggccau gaagaagaaa     1560

gacacagagg uucucuucug cuuugagcag uuugaugagc ucacccugcu gcaccuucgu     1620

gaguuugaca agaagaagcu gaucucugug gagacggaca uagucgugga ucacuacaag     1680

gaggagaagu uugaggacag guccccagcc gccgagugcc uaucagagaa ggagacggag     1740

gagcucaugg ccuggaugag aaaugugcug gggucgcgug ucaccaacgu gaaggugacc     1800

cuccgacugg acacccaccc ugccaugguc accgugcugg agaugggggc ugcccgccac     1860

uuccugcgca ugcagcagcu ggccaagacc caggaggagc gcgcacagcu ccugcagccc     1920

acgcuggaga ucaaccccag gcacgcgcuc aucaagaagc ugaaucagcu gcgcgcaagc     1980

gagccuggcc uggcucagcu gcugguggau cagauauacg agaacgccau gauugcugcu     2040

ggacuuguug acgacccuag ggccauggug ggccgcuuga augagcugcu ugucaaggcc     2100

cuggagcgac acuga                                                      2115


<210>  5995
<211>  462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000609.1__HsIGF1

<400>  5995
augggaaaaa ucagcagucu uccaacccaa uuauuuaagu gcugcuuuug ugauuucuug       60

aaggugaaga ugcacaccau guccuccucg caucucuucu accuggcgcu gugccugcuc      120

accuucacca gcucugccac ggcuggaccg gagacgcucu gcggggcuga gcugguggau      180

gcucugcagu ucgugugugg agacaggggc uuuuauuuca acaagcccac aggguauggc      240

uccagcaguc ggagggcgcc ucagacaggc aucguggaug agugcugcuu ccggagcugu      300

gaucuaagga ggcuggagau guauugcgca ccccucaagc cugccaaguc agcucgcucu      360

guccgugccc agcgccacac cgacaugccc aagacccaga aggaaguaca uuugaagaac      420

gcaaguagag ggagugcagg aaacaagaac uacaggaugu ag                         462


<210>  5996
<211>  639
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000591.1__HsIL6

<400>  5996
augaacuccu ucuccacaag cgccuucggu ccaguugccu ucucccuggg gcugcuccug       60

guguugccug cugccuuccc ugccccagua cccccaggag aagauuccaa agauguagcc      120

gccccacaca gacagccacu caccucuuca gaacgaauug acaaacaaau ucgguacauc      180

cucgacggca ucucagcccu gagaaaggag acauguaaca agaguaacau gugugaaagc      240

agcaaagagg cacuggcaga aaacaaccug aaccuuccaa agauggcuga aaaagaugga      300

ugcuuccaau cuggauucaa ugaggagacu ugccugguga aaaucaucac uggucuuuug      360

gaguuugagg uauaccuaga guaccuccag aacagauuug agaguaguga ggaacaagcc      420

agagcugugc agaugaguac aaaaguccug auccaguucc ugcagaaaaa ggcaaagaau      480

cuagaugcaa uaaccacccc ugacccaacc acaaaugcca gccugcugac gaagcugcag      540

gcacagaacc aguggcugca ggacaugaca acucaucuca uucugcgcag cuuuaaggag      600

uuccugcagu ccagccugag ggcucugcgg caaauguag                             639


<210>  5997
<211>  1281
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002183.1__HsINHBA

<400>  5997
augcccuugc uuuggcugag aggauuucug uuggcaaguu gcuggauuau agugaggagu       60

ucccccaccc caggauccga ggggcacagc gcggcccccg acuguccguc cugugcgcug      120

gccgcccucc caaaggaugu acccaacucu cagccagaga ugguggaggc cgucaagaag      180

cacauuuuaa acaugcugca cuugaagaag agacccgaug ucacccagcc gguacccaag      240

gcggcgcuuc ugaacgcgau cagaaagcug caugugggca aagucgggga gaacggguau      300

guggagauag aggaugacau uggaaggagg gcagaaauga augaacuuau ggagcagacc      360

ucggagauca ucacguuugc cgagucagga acagccagga agacgcugca cuucgagauu      420

uccaaggaag gcagugaccu gucaguggug gagcgugcag aagucuggcu guuccuaaaa      480

guccccaagg ccaacaggac caggaccaaa gucaccaucc gccucuucca gcagcagaag      540

cacccgcagg gcagcuugga cacaggggaa gaggccgagg aagugggcuu aaagggggag      600

aggagugaac uguugcucuc ugaaaaagua guagacgcuc ggaaaagcac cuggcauguc      660

uucccugucu ccagcagcau ccagcgguug cuggaccagg gcaagagcuc ccuggacguu      720

cggauugccu gugagcagug ccaggagagu ggcgccagcu ugguucuccu gggcaagaag      780

aagaagaaag aagaggaggg ggaagggaaa aagaagggcg gaggugaagg uggggcagga      840

gcagaugagg aaaaggagca gucgcacaga ccuuuccuca ugcugcaggc ccggcagucu      900

gaagaccacc cucaucgccg gcgucggcgg ggcuuggagu gugauggcaa ggucaacauc      960

ugcuguaaga aacaguucuu ugucaguuuc aaggacaucg gcuggaauga cuggaucauu     1020

gcucccucug gcuaucaugc caacuacugc gagggugagu gcccgagcca uauagcaggc     1080

acguccgggu ccucacuguc cuuccacuca acagucauca accacuaccg caugcggggc     1140

cauagccccu uugccaaccu caaaucgugc ugugugccca ccaagcugag acccaugucc     1200

auguuguacu augaugaugg ucaaaacauc aucaaaaagg acauucagaa caugaucgug     1260

gaggagugug ggugcucaua g                                               1281


<210>  5998
<211>  3459
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000623.2__HsITGAM

<400>  5998
auggcucuca gaguccuucu guuaacagcc uugaccuuau gucauggguu caacuuggac       60

acugaaaacg caaugaccuu ccaagagaac gcaaggggcu ucgggcagag cgugguccag      120

cuucagggau ccaggguggu gguuggagcc ccccaggaga uaguggcugc caaccaaagg      180

ggcagccucu accagugcga cuacagcaca ggcucaugcg agcccauccg ccugcagguc      240

cccguggagg ccgugaacau gucccugggc cugucccugg cagccaccac cagccccccu      300

cagcugcugg ccuguggucc caccgugcac cagacuugca gugagaacac guaugugaaa      360

gggcucugcu uccuguuugg auccaaccua cggcagcagc cccagaaguu cccagaggcc      420

cuccgagggu guccucaaga ggauagugac auugccuucu ugauugaugg cucugguagc      480

aucaucccac augacuuucg gcggaugaag gaguuugucu caacugugau ggagcaauua      540

aaaaagucca aaaccuuguu cucuuugaug caguacucug aagaguuccg gauucacuuu      600

accuucaaag aguuccagaa caacccuaac ccaagaucac uggugaagcc aauaacgcag      660

cugcuugggc ggacacacac ggccacgggc auccgcaaag ugguacgaga gcuguuuaac      720

aucaccaacg gagcccgaaa gaaugccuuu aagauccuag uugucaucac ggauggagaa      780

aaguuuggcg aucccuuggg auaugaggau gucaucccug aggcagacag agagggaguc      840

auucgcuacg ucauuggggu gggagaugcc uuccgcagug agaaaucccg ccaagagcuu      900

aauaccaucg cauccaagcc gccucgugau cacguguucc aggugaauaa cuuugaggcu      960

cugaagacca uucagaacca gcuucgggag aagaucuuug cgaucgaggg uacucagaca     1020

ggaaguagca gcuccuuuga gcaugagaug ucucaggaag gcuucagcgc ugccaucacc     1080

ucuaauggcc ccuugcugag cacugugggg agcuaugacu gggcuggugg agucuuucua     1140

uauacaucaa aggagaaaag caccuucauc aacaugacca gaguggauuc agacaugaau     1200

gaugcuuacu uggguuaugc ugccgccauc aucuuacgga accgggugca aagccugguu     1260

cugggggcac cucgauauca gcacaucggc cugguagcga uguucaggca gaacacuggc     1320

augugggagu ccaacgcuaa ugucaagggc acccagaucg gcgccuacuu cggggccucc     1380

cucugcuccg uggacgugga cagcaacggc agcaccgacc ugguccucau cggggccccc     1440

cauuacuacg agcagacccg agggggccag guguccgugu gccccuugcc cagggggagg     1500

gcucgguggc agugugaugc uguucucuac ggggagcagg gccaacccug gggccgcuuu     1560

ggggcagccc uaacagugcu gggggacgua aauggggaca agcugacgga cguggccauu     1620

ggggccccag gagaggagga caaccggggu gcuguuuacc uguuucacgg aaccucagga     1680

ucuggcauca gccccuccca uagccagcgg auagcaggcu ccaagcucuc ucccaggcuc     1740

caguauuuug gucagucacu gagugggggc caggaccuca caauggaugg acugguagac     1800

cugacuguag gagcccaggg gcacgugcug cugcucaggu cccagccagu acugagaguc     1860

aaggcaauca uggaguucaa ucccagggaa guggcaagga auguauuuga guguaaugau     1920

caggugguga aaggcaagga agccggagag gucagagucu gccuccaugu ccagaaaagc     1980

acacgggauc ggcuaagaga aggacagauc cagaguguug ugacuuauga ccuggcucug     2040

gacuccggcc gcccacauuc ccgcgccguc uucaaugaga caaagaacag cacacgcaga     2100

cagacacagg ucuuggggcu gacccagacu ugugagaccc ugaaacuaca guugccgaau     2160

ugcaucgagg acccagugag ccccauugug cugcgccuga acuucucucu ggugggaacg     2220

ccauugucug cuuucgggaa ccuccggcca gugcuggcgg aggaugcuca gagacucuuc     2280

acagccuugu uucccuuuga gaagaauugu ggcaaugaca acaucugcca ggaugaccuc     2340

agcaucaccu ucaguuucau gagccuggac ugccucgugg ugggugggcc ccgggaguuc     2400

aacgugacag ugacugugag aaaugauggu gaggacuccu acaggacaca ggucaccuuc     2460

uucuucccgc uugaccuguc cuaccggaag guguccacgc uccagaacca gcgcucacag     2520

cgauccuggc gccuggccug ugagucugcc uccuccaccg aagugucugg ggccuugaaa     2580

agcaccagcu gcagcauaaa ccaccccauc uucccggaaa acucagaggu caccuuuaau     2640

aucacguuug auguagacuc uaaggcuucc cuuggaaaca aacugcuccu caaggccaau     2700

gugaccagug agaacaacau gcccagaacc aacaaaaccg aguuccaacu ggagcugccg     2760

gugaaauaug cugucuacau gguggucacc agccaugggg ucuccacuaa auaucucaac     2820

uucacggccu cagagaauac cagucggguc augcagcauc aauaucaggu cagcaaccug     2880

gggcagagga gccuccccau cagccuggug uucuuggugc ccguccggcu gaaccagacu     2940

gucauauggg accgccccca ggucaccuuc uccgagaacc ucucgaguac gugccacacc     3000

aaggagcgcu ugcccucuca cuccgacuuu cuggcugagc uucggaaggc ccccguggug     3060

aacugcucca ucgcugucug ccagagaauc cagugugaca ucccguucuu uggcauccag     3120

gaagaguuca augcuacccu caaaggcaac cucucguuug acugguacau caagaccucg     3180

cauaaccacc uccugaucgu gagcacagcu gagaucuugu uuaacgauuc cguguucacc     3240

cugcugccgg gacagggggc guuugugagg ucccagacgg agaccaaagu ggagccguuc     3300

gaggucccca acccccugcc gcucaucgug ggcagcucug ucgggggacu gcugcuccug     3360

gcccucauca ccgccgcgcu guacaagcuc ggcuucuuca agcggcaaua caaggacaug     3420

augagugaag gggguccccc gggggccgaa ccccaguag                            3459


<210>  5999
<211>  1404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002415.1__HsMMP8

<400>  5999
auguucuccc ugaagacgcu uccauuucug cucuuacucc augugcagau uuccaaggcc       60

uuuccuguau cuucuaaaga gaaaaauaca aaaacuguuc aggacuaccu ggaaaaguuc      120

uaccaauuac caagcaacca guaucagucu acaaggaaga auggcacuaa ugugaucguu      180

gaaaagcuga aagaaaugca gcgauuuuuu ggguugaaug ugacggggaa gccaaaugag      240

gaaacucugg acaugaugaa aaagccucgc uguggagugc cugacagugg ugguuuuaug      300

uuaaccccag gaaaccccaa gugggaacgc acuaacuuga ccuacaggau ucgaaacuau      360

accccacagc ugucagaggc ugagguagaa agagcuauca aggaugccuu ugaacucugg      420

aguguugcau caccucucau cuucaccagg aucucacagg gagaggcaga uaucaacauu      480

gcuuuuuacc aaagagauca cggugacaau ucuccauuug auggacccaa uggaauccuu      540

gcucaugccu uucagccagg ccaagguauu ggaggagaug cucauuuuga ugccgaagaa      600

acauggacca acaccuccgc aaauuacaac uuguuucuug uugcugcuca ugaauuuggc      660

cauucuuugg ggcucgcuca cuccucugac ccuggugccu ugauguaucc caacuaugcu      720

uucagggaaa ccagcaacua cucacucccu caagaugaca ucgauggcau ucaggccauc      780

uauggacuuu caagcaaccc uauccaaccu acuggaccaa gcacacccaa acccugugac      840

cccaguuuga cauuugaugc uaucaccaca cuccguggag aaauacuuuu cuuuaaagac      900

agguacuucu ggagaaggca uccucagcua caaagagucg aaaugaauuu uauuucucua      960

uucuggccau cccuuccaac ugguauacag gcugcuuaug aagauuuuga cagagaccuc     1020

auuuuccuau uuaaaggcaa ccaauacugg gcucugagug gcuaugauau ucugcaaggu     1080

uaucccaagg auauaucaaa cuauggcuuc cccagcagcg uccaagcaau ugacgcagcu     1140

guuuucuaca gaaguaaaac auacuucuuu guaaaugacc aauucuggag auaugauaac     1200

caaagacaau ucauggagcc agguuauccc aaaagcauau caggugccuu uccaggaaua     1260

gagaguaaag uugaugcagu uuuccagcaa gaacauuucu uccaugucuu caguggacca     1320

agauauuacg cauuugaucu uauugcucag agaguuacca gaguugcaag aggcaauaaa     1380

uggcuuaacu guagauaugg cuga                                            1404


<210>  6000
<211>  2124
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_004985.2__HsMMP9

<400>  6000
augagccucu ggcagccccu gguccuggug cuccuggugc ugggcugcug cuuugcugcc       60

cccagacagc gccaguccac ccuugugcug uucccuggag accugagaac caaucucacc      120

gacaggcagc uggcagagga auaccuguac cgcuaugguu acacucgggu ggcagagaug      180

cguggagagu cgaaaucucu ggggccugcg cugcugcuuc uccagaagca acugucccug      240

cccgagaccg gugagcugga uagcgccacg cugaaggcca ugcgaacccc acggugcggg      300

gucccagacc ugggcagauu ccaaaccuuu gagggcgacc ucaaguggca ccaccacaac      360

aucaccuauu ggauccaaaa cuacucggaa gacuugccgc gggcggugau ugacgacgcc      420

uuugcccgcg ccuucgcacu guggagcgcg gugacgccgc ucaccuucac ucgcguguac      480

agccgggacg cagacaucgu cauccaguuu ggugucgcgg agcacggaga cggguauccc      540

uucgacggga aggacgggcu ccuggcacac gccuuuccuc cuggccccgg cauucaggga      600

gacgcccauu ucgacgauga cgaguugugg ucccugggca agggcgucgu gguuccaacu      660

cgguuuggaa acgcagaugg cgcggccugc cacuuccccu ucaucuucga gggccgcucc      720

uacucugccu gcaccaccga cggucgcucc gacggcuugc ccuggugcag uaccacggcc      780

aacuacgaca ccgacgaccg guuuggcuuc ugccccagcg agagacucua cacccaggac      840

ggcaaugcug augggaaacc cugccaguuu ccauucaucu uccaaggcca auccuacucc      900

gccugcacca cggacggucg cuccgacggc uaccgcuggu gcgccaccac cgccaacuac      960

gaccgggaca agcuguucgg cuucugcccg acccgagcug acucgacggu gauggggggc     1020

aacucggcgg gggagcugug cgucuucccc uucacuuucc uggguaagga guacucgacc     1080

uguaccagcg agggccgcgg agaugggcgc cucuggugcg cuaccaccuc gaacuuugac     1140

agcgacaaga aguggggcuu cugcccggac caaggauaca guuuguuccu cguggcggcg     1200

caugaguucg gccacgcgcu gggcuuagau cauuccucag ugccggaggc gcucauguac     1260

ccuauguacc gcuucacuga ggggcccccc uugcauaagg acgacgugaa uggcauccgg     1320

caccucuaug guccucgccc ugaaccugag ccacggccuc caaccaccac cacaccgcag     1380

cccacggcuc ccccgacggu cugccccacc ggacccccca cuguccaccc cucagagcgc     1440

cccacagcug gccccacagg uccccccuca gcuggcccca cagguccccc cacugcuggc     1500

ccuucuacgg ccacuacugu gccuuugagu ccgguggacg augccugcaa cgugaacauc     1560

uucgacgcca ucgcggagau ugggaaccag cuguauuugu ucaaggaugg gaaguacugg     1620

cgauucucug agggcagggg gagccggccg cagggccccu uccuuaucgc cgacaagugg     1680

cccgcgcugc cccgcaagcu ggacucgguc uuugaggagc ggcucuccaa gaagcuguuc     1740

uucuucucug ggcgccaggu guggguguac acaggcgcgu cggugcuggg cccgaggcgu     1800

cuggacaagc ugggccuggg agccgacgug gcccagguga ccggggcccu ccggaguggc     1860

agggggaaga ugcugcuguu cagcgggcgg cgccucugga gguucgacgu gaaggcgcag     1920

augguggauc cccggagcgc cagcgaggug gaccggaugu uccccggggu gccuuuggac     1980

acgcacgacg ucuuccagua ccgagagaaa gccuauuucu gccaggaccg cuucuacugg     2040

cgcgugaguu cccggaguga guugaaccag guggaccaag ugggcuacgu gaccuaugac     2100

auccugcagu gcccugagga cuag                                            2124


<210>  6001
<211>  1068
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001286.1__HsCCR1

<400>  6001
auggaaacuc caaacaccac agaggacuau gacacgacca cagaguuuga cuauggggau       60

gcaacuccgu gccagaaggu gaacgagagg gccuuugggg cccaacugcu gcccccucug      120

uacuccuugg uauuugucau uggccugguu ggaaacaucc uggugguccu gguccuugug      180

caauacaaga ggcuaaaaaa caugaccagc aucuaccucc ugaaccuggc cauuucugac      240

cugcuguucc uguucacgcu ucccuucugg aucgacuaca aguugaagga ugacuggguu      300

uuuggugaug ccauguguaa gauccucucu ggguuuuauu acacaggcuu guacagcgag      360

aucuuuuuca ucauccugcu gacgauugac agguaccugg ccaucgucca cgccguguuu      420

gccuugcggg cacggaccgu cacuuuuggu gucaucacca gcaucaucau uugggcccug      480

gccaucuugg cuuccaugcc aggcuuauac uuuuccaaga cccaauggga guucacucac      540

cacaccugua gccuucacuu uccucacgaa agccuacgag aguggaagcu guuucaggcu      600

cugaaacuga accucuuugg gcugguauug ccuuuguugg ucaugaucau cugcuacaca      660

gggauuauaa agauucugcu aagacgacca aaugagaaga aauccaaagc uguccguuug      720

auuuuuguca ucaugaucau cuuuuuucuc uuuuggaccc ccuacaauuu gacuauacuu      780

auuucuguuu uccaagacuu ccuguucacc caugagugug agcagagcag acauuuggac      840

cuggcugugc aagugacgga ggugaucgcc uacacgcacu gcugugucaa cccagugauc      900

uacgccuucg uuggugagag guuccggaag uaccugcggc aguuguucca caggcgugug      960

gcugugcacc ugguuaaaug gcuccccuuc cucuccgugg acaggcugga gagggucagc     1020

uccacaucuc ccuccacagg ggagcaugaa cucucugcug gguucuga                  1068


<210>  6002
<211>  726
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_002599.1__HsPDGFB

<400>  6002
augaaucgcu gcugggcgcu guuccugucu cucugcugcu accugcgucu ggucagcgcc       60

gagggggacc ccauucccga ggagcuuuau gagaugcuga gugaccacuc gauccgcucc      120

uuugaugauc uccaacgccu gcugcacgga gaccccggag aggaagaugg ggccgaguug      180

gaccugaaca ugacccgcuc ccacucugga ggcgagcugg agagcuuggc ucguggaaga      240

aggagccugg guucccugac cauugcugag ccggccauga ucgccgagug caagacgcgc      300

accgaggugu ucgagaucuc ccggcgccuc auagaccgca ccaacgccaa cuuccuggug      360

uggccgcccu guguggaggu gcagcgcugc uccggcugcu gcaacaaccg caacgugcag      420

ugccgcccca cccaggugca gcugcgaccu guccagguga gaaagaucga gauugugcgg      480

aagaagccaa ucuuuaagaa ggccacggug acgcuggaag accaccuggc augcaagugu      540

gagacagugg cagcugcacg gccugugacc cgaagcccgg gggguuccca ggagcagcga      600

gccaaaacgc cccaaacucg ggugaccauu cggacggugc gaguccgccg gccccccaag      660

ggcaagcacc ggaaauucaa gcacacgcau gacaagacgg cacugaagga gacccuugga      720

gccuag                                                                 726


<210>  6003
<211>  1095
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_149126.1__HsPDGFD

<400>  6003
augcaccggc ucaucuuugu cuacacucua aucugcgcaa acuuuugcag cugucgggac       60

acuucugcaa ccccgcagag cgcauccauc aaagcauugc gcaacgccaa ccucaggcga      120

gaugacuugu accgaagaga ugagaccauc caggugaaag gaaacggcua cgugcagagu      180

ccuagauucc cgaacagcua ccccaggaac cugcuccuga cauggcggcu ucacucucag      240

gagaauacac ggauacagcu aguguuugac aaucaguuug gauuagagga agcagaaaau      300

gauaucugua gguaugauuu uguggaaguu gaagauauau ccgaaaccag uaccauuauu      360

agaggacgau gguguggaca caaggaaguu ccuccaagga uaaaaucaag aacgaaccaa      420

auuaaaauca cauucaaguc cgaugacuac uuuguggcua aaccuggauu caagauuuau      480

uauucuuugc uggaagauuu ccaacccgca gcagcuucag agaccaacug ggaaucuguc      540

acaagcucua uuucaggggu auccuauaac ucuccaucag uaacggaucc cacucugauu      600

gcggaugcuc uggacaaaaa aauugcagaa uuugauacag uggaagaucu gcucaaguac      660

uucaauccag agucauggca agaagaucuu gagaauaugu aucuggacac cccucgguau      720

cgaggcaggu cauaccauga ccggaaguca aaaguugacc uggauaggcu caaugaugau      780

gccaagcguu acaguugcac ucccaggaau uacucgguca auauaagaga agaacugaag      840

uuggccaaug uggucuucuu uccacguugc cuccucgugc agcgcugugg aggaaauugu      900

ggcuguggaa cugucaacug gagguccugc acaugcaauu cagggaaaac cgugaaaaag      960

uaucaugagg uauuacaguu ugagccuggc cacaucaaga ggagggguag agcuaagacc     1020

auggcucuag uugacaucca guuggaucac caugaacgau gugauuguau cugcagcuca     1080

agaccaccuc gauaa                                                      1095


<210>  6004
<211>  678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_003946.3__HsSOCS3

<400>  6004
auggucaccc acagcaaguu ucccgccgcc gggaugagcc gcccccugga caccagccug       60

cgccucaaga ccuucagcuc caagagcgag uaccagcugg uggugaacgc agugcgcaag      120

cugcaggaga gcggcuucua cuggagcgca gugaccggcg gcgaggcgaa ccugcugcuc      180

agugccgagc ccgccggcac cuuucugauc cgcgacagcu cggaccagcg ccacuucuuc      240

acgcucagcg ucaagaccca gucugggacc aagaaccugc gcauccagug ugaggggggc      300

agcuucucuc ugcagagcga uccccggagc acgcagcccg ugccccgcuu cgacugcgug      360

cucaagcugg ugcaccacua caugccgccc ccuggagccc ccuccuuccc cucgccaccu      420

acugaacccu ccuccgaggu gcccgagcag ccgucugccc agccacuccc ugggaguccc      480

cccagaaggg ccuauuacau cuacuccggg ggcgagaaga ucccccuggu guugagccgg      540

ccccucuccu ccaacguggc cacucuucag caucucuguc ggaagaccgu caacggccac      600

cuggacuccu augagaaagu cacccagcug ccggggccca uucgggaguu ccuggaccag      660

uacgaugccc cgcuuuaa                                                    678


<210>  6005
<211>  1173
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_000651.3__HsTGFB1

<400>  6005
augccgcccu ccgggcugcg gcugcugccg cugcugcuac cgcugcugug gcuacuggug       60

cugacgccug gccggccggc cgcgggacua uccaccugua agacuaucga cauggagcug      120

gugaagcgga agcgcaucga ggccauccgc ggccagaucc uguccaagcu gcggcucgcc      180

agccccccga gccaggggga ggugccgccc ggcccgcugc ccgaggccgu gcucgcccug      240

uacaacagca cccgcgaccg gguggccggg gagagugcag aaccggagcc cgagccugag      300

gccgacuacu acgccaagga ggucacccgc gugcuaaugg uggaaaccca caacgaaauc      360

uaugacaagu ucaagcagag uacacacagc auauauaugu ucuucaacac aucagagcuc      420

cgagaagcgg uaccugaacc cguguugcuc ucccgggcag agcugcgucu gcugaggcuc      480

aaguuaaaag uggagcagca cguggagcug uaccagaaau acagcaacaa uuccuggcga      540

uaccucagca accggcugcu ggcacccagc gacucgccag agugguuauc uuuugauguc      600

accggaguug ugcggcagug guugagccgu ggaggggaaa uugagggcuu ucgccuuagc      660

gcccacugcu ccugugacag cagggauaac acacugcaag uggacaucaa cggguucacu      720

accggccgcc gaggugaccu ggccaccauu cauggcauga accggccuuu ccugcuucuc      780

auggccaccc cgcuggagag ggcccagcau cugcaaagcu cccggcaccg ccgagcccug      840

gacaccaacu auugcuucag cuccacggag aagaacugcu gcgugcggca gcuguacauu      900

gacuuccgca aggaccucgg cuggaagugg auccacgagc ccaagggcua ccaugccaac      960

uucugccucg ggcccugccc cuacauuugg agccuggaca cgcaguacag caagguccug     1020

gcccuguaca accagcauaa cccgggcgcc ucggcggcgc cgugcugcgu gccgcaggcg     1080

cuggagccgc ugcccaucgu guacuacgug ggccgcaagc ccaaggugga gcagcugucc     1140

aacaugaucg ugcgcuccug caagugcagc uga                                  1173


<210>  6006
<211>  1245
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_003229.1__HsTGFB2

<400>  6006
augcacuacu gugugcugag cgcuuuucug auccugcauc uggucacggu cgcgcucagc       60

cugucuaccu gcagcacacu cgauauggac caguucaugc gcaagaggau cgaggcgauc      120

cgcgggcaga uccugagcaa gcugaagcuc accagucccc cagaagacua uccugagccc      180

gaggaagucc ccccggaggu gauuuccauc uacaacagca ccagggacuu gcuccaggag      240

aaggcgagcc ggagggcggc cgccugcgag cgcgagagga gcgacgaaga guacuacgcc      300

aaggagguuu acaaaauaga caugccgccc uucuuccccu ccgaaaaugc caucccgccc      360

acuuucuaca gacccuacuu cagaauuguu cgauuugacg ucucagcaau ggagaagaau      420

gcuuccaauu uggugaaagc agaguucaga gucuuucguu ugcagaaccc aaaagccaga      480

gugccugaac aacggauuga gcuauaucag auucucaagu ccaaagauuu aacaucucca      540

acccagcgcu acaucgacag caaaguugug aaaacaagag cagaaggcga auggcucucc      600

uucgauguaa cugaugcugu ucaugaaugg cuucaccaua aagacaggaa ccugggauuu      660

aaaauuagcu uacacugucc cugcugcacu uuuguaccau cuaauaauua caucauccca      720

aauaaaagug aagaacuaga agcaagauuu gcagguauug auggcaccuc cacauauacc      780

aguggugauc agaaaacuau aaaguccacu aggaaaaaaa acagugggaa gaccccacau      840

cuccugcuaa uguuauugcc cuccuacaga cuugagucac aacagaccaa ccggcggaag      900

aagcgugcuu uggaugcggc cuauugcuuu agaaaugugc aggauaauug cugccuacgu      960

ccacuuuaca uugauuucaa gagggaucua ggguggaaau ggauacacga acccaaaggg     1020

uacaaugcca acuucugugc uggagcaugc ccguauuuau ggaguucaga cacucagcac     1080

agcagggucc ugagcuuaua uaauaccaua aauccagaag caucugcuuc uccuugcugc     1140

gugucccaag auuuagaacc ucuaaccauu cucuacuaca uuggcaaaac acccaagauu     1200

gaacagcuuu cuaauaugau uguaaagucu ugcaaaugca gcuaa                     1245


<210>  6007
<211>  1239
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_003230.1__HsTGFB3

<400>  6007
augaagaugc acuugcaaag ggcucuggug guccuggccc ugcugaacuu ugccacgguc       60

agccucucuc uguccacuug caccaccuug gacuucggcc acaucaagaa gaagagggug      120

gaagccauua ggggacagau cuugagcaag cucaggcuca ccagcccccc ugagccaacg      180

gugaugaccc acguccccua ucagguccug gcccuuuaca acagcacccg ggagcugcug      240

gaggagaugc auggggagag ggaggaaggc ugcacccagg aaaacaccga gucggaauac      300

uaugccaaag aaauccauaa auucgacaug auccaggggc uggcggagca caacgaacug      360

gcugucugcc cuaaaggaau uaccuccaag guuuuccgcu ucaauguguc cucaguggag      420

aaaaauagaa ccaaccuauu ccgagcagag uuccgggucu ugcgggugcc caaccccagc      480

ucuaagcgga augagcagag gaucgagcug uuccagaucc uucggccaga ugagcacauu      540

gccaaacagc gcuauaucgg uggcaagaau cugcccacac ggggcacugc cgaguggcug      600

uccuuugaug ucacugacac ugugcgugag uggcuguuga gaagagaguc caacuuaggu      660

cuagaaauca gcauucacug uccaugucac accuuucagc ccaauggaga uauccuggaa      720

aacauucacg aggugaugga aaucaaauuc aaaggcgugg acaaugagga ugaccauggc      780

cguggagauc uggggcgccu caagaagcag aaggaucacc acaacccuca ucuaauccuc      840

augaugauuc ccccacaccg gcucgacaac ccgggccagg ggggucagag gaagaagcgg      900

gcuuuggaca ccaauuacug cuuccgcaac uuggaggaga acugcugugu gcgcccccuc      960

uacauugacu uccgacagga ucugggcugg aagugggucc augaaccuaa gggcuacuau     1020

gccaacuucu gcucaggccc uugcccauac cuccgcagug cagacacaac ccacagcacg     1080

gugcugggac uguacaacac ucugaacccu gaagcaucug ccucgccuug cugcgugccc     1140

caggaccugg agccccugac cauccuguac uauguuggga ggacccccaa aguggagcag     1200

cucuccaaca ugguggugaa gucuuguaaa uguagcuga                            1239


<210>  6008
<211>  1386
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_001057.1__HsTNFRSF1B

<400>  6008
auggcgcccg ucgccgucug ggccgcgcug gccgucggac uggagcucug ggcugcggcg       60

cacgccuugc ccgcccaggu ggcauuuaca cccuacgccc cggagcccgg gagcacaugc      120

cggcucagag aauacuauga ccagacagcu cagaugugcu gcagcaaaug cucgccgggc      180

caacaugcaa aagucuucug uaccaagacc ucggacaccg ugugugacuc cugugaggac      240

agcacauaca cccagcucug gaacuggguu cccgagugcu ugagcugugg cucccgcugu      300

agcucugacc agguggaaac ucaagccugc acucgggaac agaaccgcau cugcaccugu      360

aggcccggcu gguacugcgc gcugagcaag caggaggggu gccggcugug cgcgccgcug      420

cgcaagugcc gcccgggcuu cggcguggcc agaccaggaa cugaaacauc agacguggug      480

ugcaagcccu gugccccggg gacguucucc aacacgacuu cauccacgga uauuugcagg      540

ccccaccaga ucuguaacgu gguggccauc ccugggaaug caagcaugga ugcagucugc      600

acguccacgu cccccacccg gaguauggcc ccaggggcag uacacuuacc ccagccagug      660

uccacacgau cccaacacac gcagccaacu ccagaaccca gcacugcucc aagcaccucc      720

uuccugcucc caaugggccc cagcccccca gcugaaggga gcacuggcga cuucgcucug      780

ccaguuggac ugauuguggg ugugacagcc uugggucuac uaauaauagg aguggugaac      840

ugugucauca ugacccaggu gaaaaagaag cccuugugcc ugcagagaga agccaaggug      900

ccucacuugc cugccgauaa ggcccggggu acacagggcc ccgagcagca gcaccuccug      960

aucacagcgc cgagcuccag cagcagcucc cuggagagcu cggccagugc guuggacaga     1020

agggcgccca cucggaacca gccacaggca ccaggcgugg aggccagugg ggccggggag     1080

gcccgggcca gcaccgggag cucagauucu uccccuggug gccaugggac ccaggucaau     1140

gucaccugua ucgugaacgu cuguagcagc ucugaccaca gcucacagug cuccucccaa     1200

gccagcucca caaugggaga cacagauucc agccccucgg aguccccgaa ggacgagcag     1260

guccccuucu ccaaggagga augugccuuu cggucacagc uggagacgcc agagacccug     1320

cuggggagca ccgaagagaa gccccugccc cuuggagugc cugaugcugg gaugaagccc     1380

aguuaa                                                                1386


<210>  6009
<211>  1065
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  derived and/or modified CDS sequence (wt) from Homo 
       sapiens__NP_004460.1__HsVEGFD

<400>  6009
auguacagag aguggguagu ggugaauguu uucaugaugu uguacgucca gcuggugcag       60

ggcuccagua augaacaugg accagugaag cgaucaucuc aguccacauu ggaacgaucu      120

gaacagcaga ucagggcugc uucuaguuug gaggaacuac uucgaauuac ucacucugag      180

gacuggaagc uguggagaug caggcugagg cucaaaaguu uuaccaguau ggacucucgc      240

ucagcauccc aucgguccac uagguuugcg gcaacuuucu augacauuga aacacuaaaa      300

guuauagaug aagaauggca aagaacucag ugcagcccua gagaaacgug cguggaggug      360

gccagugagc uggggaagag uaccaacaca uucuucaagc ccccuugugu gaacguguuc      420

cgauguggug gcuguugcaa ugaagagagc cuuaucugua ugaacaccag caccucguac      480

auuuccaaac agcucuuuga gauaucagug ccuuugacau caguaccuga auuagugccu      540

guuaaaguug ccaaucauac agguuguaag ugcuugccaa cagccccccg ccauccauac      600

ucaauuauca gaagauccau ccagaucccu gaagaagauc gcuguuccca uuccaagaaa      660

cucuguccua uugacaugcu augggauagc aacaaaugua aauguguuuu gcaggaggaa      720

aauccacuug cuggaacaga agaccacucu caucuccagg aaccagcucu cugugggcca      780

cacaugaugu uugacgaaga ucguugcgag ugugucugua aaacaccaug ucccaaagau      840

cuaauccagc accccaaaaa cugcaguugc uuugagugca aagaaagucu ggagaccugc      900

ugccagaagc acaagcuauu ucacccagac accuguagcu gugaggacag augccccuuu      960

cauaccagac caugugcaag uggcaaaaca gcaugugcaa agcauugccg cuuuccaaag     1020

gagaaaaggg cugcccaggg gccccacagc cgaaagaauc cuuga                     1065


<210>  6010
<211>  751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (wt)

<400>  6010
gggagaaagc uuaccauggg gaccuggauu uuguuugcuu gccuccuggg agcagccuuc       60

ucuaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuauauaaga      120

cauccguaca cuuccuaugg guacgaaccc auggguggau ggcugcacca ccaaaucaua      180

cccguggugu cgcagcagac uccccagagu caugcccuuc agccucauca ccacaucccc      240

auggugccag cucaacagcc cgggaucccc cagcagccaa ugaugccacu uccuggccaa      300

cacuccauga cuccaaccca acaccaccag ccaaaccucc cucugcccgc ccagcagccc      360

uuccagcccc agcccgucca gccccagccu caccagcccc ugcagcccca gucacccaug      420

caccccaucc agcccuugcu gccacagcca ccucugccuc cgauguucuc caugcagucu      480

cugcuuccug accugccucu ggaagcaugg ccagcaacag acaagaccaa gcgggaggaa      540

guggauuaag gacuaguuau aagacugacu agcccgaugg gccucccaac gggcccuccu      600

ccccuccuug caccgagauu aauaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc      720

cccaaaggcu cuuuucagag ccaccagaau u                                     751


<210>  6011
<211>  787
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (wt)

<400>  6011
gggagaaagc uuaccauggg gaccuggauu uucuuugccu gccuuuuggg agcaucccuu       60

gcuaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug      120

cuuaccccuc ugaaguggua ccagaacaug auaagacauc cguacacuuc cuauggguac      180

gaacccaugg guggauggcu gcaccaccaa aucauacccg uggugucgca gcagacuccc      240

cagagucaug cccuucagcc ucaucaccac auccccaugg ugccagcuca acagcccggg      300

aucccccagc agccaaugau gccacuuccu ggccaacacu ccaugacucc aacccaacac      360

caccagccaa accucccucu gcccgcccag cagcccuucc agccccagcc cguccagccc      420

cagccucacc agccccugca gccccaguca cccaugcacc ccauccagcc cuugcugcca      480

cagccaccuc ugccuccgau guucuccaug cagucucugc uuccugaccu gccucuggaa      540

gcauggccag caacagacaa gaccaagcgg gaggaagugg auuaaggacu aguuauaaga      600

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      780

cagaauu                                                                787


<210>  6012
<211>  436
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (wt)

<400>  6012
gggagaaagc uuaccauggg gaccuggauu uuguuugcuu gccuccuggg agcagccuuc       60

ucuaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug      120

cuuaccccuc ugaaguggua ccagaacaug auaagacauc cgucucugcu uccugaccug      180

ccucuggaag cauggccagc aacagacaag accaagcggg aggaagugga uuaaggacua      240

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      300

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      420

cagagccacc agaauu                                                      436


<210>  6013
<211>  829
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (wt)

<400>  6013
gggagaaagc uuaccauggg gaccuggauu uuguuugcuu gccuccuggg agcagccuuc       60

ucuaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggac      120

uuauacuugg aggcuauccg uauugacagg acugcauucg ugcuuacccc ucugaagugg      180

uaccagaaca ugauaagaca uccguacacu uccuaugguu acgaacccau ggguggaugg      240

cugcaccacc aaaucauucc cguggugucg cagcagacuc cccagaguca ugcccuucag      300

ccucaucacc acauccccau ggugccagcu caacagcccg ggauccccca gcagccaaug      360

augccacuuc cuggccaaca cuccaugacu ccaacccaac accaccagcc aaaccucccu      420

cugcccgccc agcagcccuu ccagccccag cccguccagc cccagccuca ccagccccug      480

cagccccagu cacccaugca ccccauccag cccuugcugc cacagccacc ucugccuccg      540

auguucucca ugcagucucu gcuuccugac cugccucugg aagcauggcc agcaacagac      600

aagaccaagc gggaggaagu ggauuaagga cuaguuauaa gacugacuag cccgaugggc      660

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc      780

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                  829


<210>  6014
<211>  715
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (wt)

<400>  6014
gggagaaagc uuaccauggg gaccuggauu uuguuugcuu gccuccuggg agcagccuuc       60

ucuaugccuc uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug      120

cuuaccccuc ugaaguggua ccagaacaug auaagacauc cgacucccca gagucaugcc      180

cuucagccuc aucaccacau ccccauggug ccagcucaac agcccgggau cccccagcag      240

ccaaugaugc cacuuccugg ccaacacucc augacuccaa cccaacacca ccagccaaac      300

cucccucugc ccgcccagca gcccuuccag ccccagcccg uccagcccca gccucaccag      360

ccccugcagc cccagucacc caugcacccc auccagcccu ugcugccaca gccaccucug      420

ccuccgaugu ucuccaugca gucucugcuu ccugaccugc cucuggaagc auggccagca      480

acagacaaga ccaagcggga ggaaguggau uaaggacuag uuauaagacu gacuagcccg      540

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      660

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           715


<210>  6015
<211>  739
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (wt)

<400>  6015
gggagaaagc uuaccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc       60

agcuaugagg ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccguacacu      120

uccuaugggu acgaacccau ggguggaugg cugcaccacc aaaucauacc cguggugucg      180

cagcagacuc cccagaguca ugcccuucag ccucaucacc acauccccau ggugccagcu      240

caacagcccg ggauccccca gcagccaaug augccacuuc cuggccaaca cuccaugacu      300

ccaacccaac accaccagcc aaaccucccu cugcccgccc agcagcccuu ccagccccag      360

cccguccagc cccagccuca ccagccccug cagccccagu cacccaugca ccccauccag      420

cccuugcugc cacagccacc ucugccuccg auguucucca ugcagucucu gcuuccugac      480

cugccucugg aagcauggcc agcaacagac aagaccaagc gggaggaagu ggauuaagga      540

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      600

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      720

uuucagagcc accagaauu                                                   739


<210>  6016
<211>  3178
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (wt)

<400>  6016
gggagaaagc uuaccaugcc cggcguggcc cgccugccgc ugcugcucgg gcugcugcug       60

cucccgcguc ccggccggcc gcuggacuug gccgacuaca ccuaugaccu ggcggaggag      120

gacgacucgg agccccucaa cuacaaagac cccugcaagg cggcugccuu ucuuggggac      180

auugcccugg acgaagagga ccugagggcc uuccagguac agcaggcugu ggaucucaga      240

cggcacacag cucguaaguc cuccaucaaa gcugcaguuc caggaaacac uucuaccccc      300

agcugccaga gcaccaacgg gcagccucag aggggagccu gugggagaug gagagguaga      360

ucccguagcc ggcgggcggc gacgucccga ccagagcgug uguggcccga uggggucauc      420

cccuuuguca uugggggaaa cuucacuggu agccagaggg cagucuuccg gcaggccaug      480

aggcacuggg agaagcacac cugugucacc uuccuggagc gcacugacga ggacagcuau      540

auuguguuca ccuaucgacc uugcgggugc ugcuccuacg ugggucgccg cggcgggggc      600

ccccaggcca ucuccaucgg caagaacugu gacaaguucg gcauuguggu ccacgagcug      660

ggccacgucg ucggcuucug gcacgaacac acucggccag accgggaccg ccacguuucc      720

aucguucgug agaacaucca gccagggcag gaguauaacu uccugaagau ggagccucag      780

gagguggagu cccuggggga gaccuaugac uucgacagca ucaugcauua cgcucggaac      840

acauucucca ggggcaucuu ccuggauacc auugucccca aguaugaggu gaacggggug      900

aaaccuccca uuggccaaag gacacggcuc agcaaggggg acauugccca agcccgcaag      960

cuguacaagu gcccagccug uggagagacc cugcaagaca gcacaggcaa cuucuccucc     1020

ccugaauacc ccaauggcua cucugcucac augcacugcg uguggcgcau cucugucaca     1080

cccggggaga agaucauccu gaacuucacg ucccuggacc uguaccgcag ccgccugugc     1140

ugguacgacu auguggaggu ccgagauggc uucuggagga aggcgccccu ccgaggccgc     1200

uucugcgggu ccaaacuccc ugagccuauc gucuccacug acagccgccu cuggguugag     1260

uuccgcagca gcagcaauug gguuggaaag ggcuucuuug cagucuacga agccaucugc     1320

gggggugaug ugaaaaagga cuauggccac auucaaucgc ccaacuaccc agacgauuac     1380

cggcccagca aagucugcau cuggcggauc caggugucug agggcuucca cgugggccuc     1440

acauuccagu ccuuugagau ugagcgccac gacagcugug ccuacgacua ucuggaggug     1500

cgcgacgggc acagugagag cagcacccuc aucgggcgcu acuguggcua ugagaagccu     1560

gaugacauca agagcacguc cagccgccuc uggcucaagu ucgucucuga cggguccauu     1620

aacaaagcgg gcuuugccgu caacuuuuuc aaagaggugg acgagugcuc ucggcccaac     1680

cgcgggggcu gugagcagcg gugccucaac acccugggca gcuacaagug cagcugugac     1740

cccggguacg agcuggcccc agacaagcgc cgcugugagg cugcuugugg cggauuccuc     1800

accaagcuca acggcuccau caccagcccg ggcuggccca aggaguaccc ccccaacaag     1860

aacugcaucu ggcagcuggu ggcccccacc caguaccgca ucucccugca guuugacuuc     1920

uuugagacag agggcaauga ugugugcaag uacgacuucg uggaggugcg caguggacuc     1980

acagcugacu ccaagcugca uggcaaguuc ugugguucug agaagcccga ggucaucacc     2040

ucccaguaca acaacaugcg cguggaguuc aaguccgaca acaccguguc caaaaagggc     2100

uucaaggccc acuucuucuc agacaaggac gagugcucca aggauaacgg cggcugccag     2160

caggacugcg ucaacacguu cggcaguuau gagugccaau gccgcagugg cuucguccuc     2220

caugacaaca agcacgacug caaagaagcc ggcugugacc acaaggugac auccaccagu     2280

gguaccauca ccagccccaa cuggccugac aaguauccca gcaagaagga gugcacgugg     2340

gccaucucca gcacccccgg gcaccggguc aagcugaccu ucauggagau ggacaucgag     2400

ucccagccug agugugccua cgaccaccua gagguguucg acgggcgaga cgccaaggcc     2460

cccguccucg gccgcuucug ugggagcaag aagcccgagc ccguccuggc cacaggcagc     2520

cgcauguucc ugcgcuucua cucagauaac ucgguccagc gaaagggcuu ccaggccucc     2580

cacgccacag agugcggggg ccagguacgg gcagacguga agaccaagga ccuuuacucc     2640

cacgcccagu uuggcgacaa caacuacccu gggggugugg acugugagug ggucauugug     2700

gccgaggaag gcuacggcgu ggagcucgug uuccagaccu uugaggugga ggaggagacc     2760

gacugcggcu augacuacau ggagcuguuc gacggcuacg acagcacagc ccccaggcug     2820

gggcgcuacu guggcucagg gccuccugag gagguguacu cggcgggaga uucuguccug     2880

gugaaguucc acucggauga caccaucacc aaaaaagguu uccaccuccg auacaccagc     2940

accaaguucc aggacacacu ccacagcagg aagugaggac uaguuauaag acugacuagc     3000

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     3060

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     3120

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       3178


<210>  6017
<211>  1408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (wt)

<400>  6017
gggagaaagc uuaccauggu ggccgggacc cgcugucuuc uagcguugcu gcuuccccag       60

guccuccugg gcggcgcggc uggccucguu ccggagcugg gccgcaggaa guucgcggcg      120

gcgucgucgg gccgccccuc aucccagccc ucugacgagg uccugagcga guucgaguug      180

cggcugcuca gcauguucgg ccugaaacag agacccaccc ccagcaggga cgccguggug      240

ccccccuaca ugcuagaccu guaucgcagg cacucagguc agccgggcuc acccgcccca      300

gaccaccggu uggagagggc agccagccga gccaacacug ugcgcagcuu ccaccaugaa      360

gaaucuuugg aagaacuacc agaaacgagu gggaaaacaa cccggagauu cuucuuuaau      420

uuaaguucua uccccacgga ggaguuuauc accucagcag agcuucaggu uuuccgagaa      480

cagaugcaag augcuuuagg aaacaauagc aguuuccauc accgaauuaa uauuuaugaa      540

aucauaaaac cugcaacagc caacucgaaa uuccccguga ccagacuuuu ggacaccagg      600

uuggugaauc agaaugcaag cagaugggaa aguuuugaug ucacccccgc ugugaugcgg      660

uggacugcac agggacacgc caaccaugga uucguggugg aaguggccca cuuggaggag      720

aaacaaggug ucuccaagag acauguuagg auaagcaggu cuuugcacca agaugaacac      780

agcuggucac agauaaggcc auugcuagua acuuuuggcc augauggaaa agggcauccu      840

cuccacaaaa gagaaaaacg ucaagccaaa cacaaacagc ggaaacgccu uaaguccagc      900

uguaagagac acccuuugua cguggacuuc agugacgugg gguggaauga cuggauugug      960

gcucccccgg gguaucacgc cuuuuacugc cacggagaau gcccuuuucc ucuggcugau     1020

caucugaacu ccacuaauca ugccauuguu cagacguugg ucaacucugu uaacucuaag     1080

auuccuaagg caugcugugu cccgacagaa cucagugcua ucucgaugcu guaccuugac     1140

gagaaugaaa agguuguauu aaagaacuau caggacaugg uuguggaggg uugugggugu     1200

cgcuagggac uaguuauaag acugacuagc ccgaugggcc ucccaacggg cccuccuccc     1260

cuccuugcac cgagauuaau aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1380

aaaggcucuu uucagagcca ccagaauu                                        1408


<210>  6018
<211>  1444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (wt)

<400>  6018
gggagaaagc uuaccaugau uccugguaac cgaaugcuga uggucguuuu auuaugccaa       60

guccugcuag gaggcgcgag ccaugcuagu uugauaccug agacggggaa gaaaaaaguc      120

gccgagauuc agggccacgc gggaggacgc cgcucagggc agagccauga gcuccugcgg      180

gacuucgagg cgacacuucu gcagauguuu gggcugcgcc gccgcccgca gccuagcaag      240

agugccguca uuccggacua caugcgggau cuuuaccggc uucagucugg ggaggaggag      300

gaagaacaga uccacagcac uggucuugag uauccugagc gcccggccag ccgggccaac      360

accgugagga gcuuccacca cgaagaacau cuggagaaca ucccagggac cagugaaaac      420

ucugcuuuuc guuuccucuu uaaccucagc agcaucccug agaacgaggu gaucuccucu      480

gcagagcuuc ggcuguuccg ggagcagguc gaccagggcc cugauuggga aaggggcuuc      540

caccguauaa acauuuauga gguuaugaag cccccagcag aaguggugcc ugggcaccuc      600

aucacacgac uacuggacac gagacugguc caccacaaug ugacacggug ggaaacuuuu      660

gaugugagcc cugcgguccu ucgcuggacc cgggagaagc agccaaacua ugggcuagcc      720

auugagguga cucaccucca ucagacucgg acccaccagg gccagcaugu caggauuagc      780

cgaucguuac cucaagggag ugggaauugg gcccagcucc ggccccuccu ggucaccuuu      840

ggccaugaug gccggggcca ugccuugacc cgacgccgga gggccaagcg uagcccuaag      900

caucacucac agcgggccag gaagaagaau aagaacugcc ggcgccacuc gcucuaugug      960

gacuucagcg augugggcug gaaugacugg auuguggccc caccaggcua ccaggccuuc     1020

uacugccaug gggacugccc cuuuccacug gcugaccacc ucaacucaac caaccaugcc     1080

auugugcaga cccuggucaa uucugucaau uccaguaucc ccaaagccug uugugugccc     1140

acugaacuga gugccaucuc caugcuguac cuggaugagu augauaaggu gguacugaaa     1200

aauuaucagg agaugguagu agagggaugu gggugccgcu gaggacuagu uauaagacug     1260

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1440

aauu                                                                  1444


<210>  6019
<211>  1759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (wt)

<400>  6019
gggagaaagc uuaccaugcc ggggcugggg cggagggcgc aguggcugug cugguggugg       60

gggcugcugu gcagcugcug cgggcccccg ccgcugcggc cgcccuugcc cgcugccgcg      120

gccgccgccg ccggggggca gcugcugggg gacggcggga gccccggccg cacggagcag      180

ccgccgccgu cgccgcaguc cuccucgggc uuccuguacc ggcggcucaa gacgcaggag      240

aagcgggaga ugcagaagga gaucuugucg gugcuggggc ucccgcaccg gccccggccc      300

cugcacggcc uccaacagcc gcagcccccg gcgcuccggc agcaggagga gcagcagcag      360

cagcagcagc ugccucgcgg agagcccccu cccgggcgac ugaaguccgc gccccucuuc      420

augcuggauc uguacaacgc ccuguccgcc gacaacgacg aggacggggc gucggagggg      480

gagaggcagc aguccuggcc ccacgaagca gccagcucgu cccagcgucg gcagccgccc      540

ccgggcgccg cgcacccgcu caaccgcaag agccuucugg cccccggauc uggcagcggc      600

ggcgcguccc cacugaccag cgcgcaggac agcgccuucc ucaacgacgc ggacaugguc      660

augagcuuug ugaaccuggu ggaguacgac aaggaguucu ccccucguca gcgacaccac      720

aaagaguuca aguucaacuu aucccagauu ccugagggug agguggugac ggcugcagag      780

uuccgcaucu acaaggacug uguuaugggg aguuuuaaaa accaaacuuu ucuuaucagc      840

auuuaucaag ucuuacagga gcaucagcac agagacucug accuguuuuu guuggacacc      900

cguguaguau gggccucaga agaaggcugg cuggaauuug acaucacggc cacuagcaau      960

cuguggguug ugacuccaca gcauaacaug gggcuucagc ugagcguggu gacaagggau     1020

ggaguccacg uccacccccg agccgcaggc cuggugggca gagacggccc uuacgacaag     1080

cagcccuuca ugguggcuuu cuucaaagug agugaggugc acgugcgcac caccagguca     1140

gccuccagcc ggcgccgaca acagagucgu aaucgcucua cccaguccca ggacguggcg     1200

cgggucucca gugcuucaga uuacaacagc agugaauuga aaacagccug caggaagcau     1260

gagcuguaug ugaguuucca agaccuggga uggcaggacu ggaucauugc acccaagggc     1320

uaugcugcca auuacuguga uggagaaugc uccuucccac ucaacgcaca caugaaugca     1380

accaaccacg cgauugugca gaccuugguu caccuuauga accccgagua uguccccaaa     1440

ccgugcugug cgccaacuaa gcuaaaugcc aucucgguuc uuuacuuuga ugacaacucc     1500

aaugucauuc ugaaaaaaua caggaauaug guuguaagag cuuguggaug ccacuaagga     1560

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca     1620

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     1740

uuucagagcc accagaauu                                                  1759


<210>  6020
<211>  1513
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (wt)

<400>  6020
gggagaaagc uuaccaugca cgugcgcuca cugcgagcug cggcgccgca cagcuucgug       60

gcgcucuggg caccccuguu ccugcugcgc uccgcccugg ccgacuucag ccuggacaac      120

gaggugcacu cgagcuucau ccaccggcgc cuccgcagcc aggagcggcg ggagaugcag      180

cgcgagaucc ucuccauuuu gggcuugccc caccgcccgc gcccgcaccu ccagggcaag      240

cacaacucgg cacccauguu caugcuggac cuguacaacg ccauggcggu ggaggagggc      300

ggcgggcccg gcggccaggg cuucuccuac cccuacaagg ccgucuucag uacccagggc      360

cccccucugg ccagccugca agauagccau uuccucaccg acgccgacau ggucaugagc      420

uucgucaacc ucguggaaca ugacaaggag uucuuccacc cacgcuacca ccaucgagag      480

uuccgguuug aucuuuccaa gaucccagaa ggggaagcug ucacggcagc cgaguuccgg      540

aucuacaagg acuacauccg ggaacgcuuc gacaaugaga cguuccggau cagcguuuau      600

caggugcucc aggagcacuu gggcagggaa ucggaucucu uccugcucga cagccguacc      660

cucugggccu cggaggaggg cuggcuggug uuugacauca cagccaccag caaccacugg      720

guggucaauc cgcggcacaa ccugggccug cagcucucgg uggagacgcu ggaugggcag      780

agcaucaacc ccaaguuggc gggccugauu gggcggcacg ggccccagaa caagcagccc      840

uucauggugg cuuucuucaa ggccacggag guccacuucc gcagcauccg guccacgggg      900

agcaaacagc gcagccagaa ccgcuccaag acgcccaaga accaggaagc ccugcggaug      960

gccaacgugg cagagaacag cagcagcgac cagaggcagg ccuguaagaa gcacgagcug     1020

uaugucagcu uccgagaccu gggcuggcag gacuggauca ucgcgccuga aggcuacgcc     1080

gccuacuacu gugaggggga gugugccuuc ccucugaacu ccuacaugaa cgccaccaac     1140

cacgccaucg ugcagacgcu gguccacuuc aucaacccgg aaacggugcc caagcccugc     1200

ugugcgccca cgcagcucaa ugccaucucc guccucuacu ucgaugacag cuccaacguc     1260

auccugaaga aauacagaaa cauggugguc cgggccugug gcugccacua gggacuaguu     1320

auaagacuga cuagcccgau gggccuccca acgggcccuc cuccccuccu ugcaccgaga     1380

uuaauaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1500

agccaccaga auu                                                        1513


<210>  6021
<211>  517
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (wt)

<400>  6021
gggagaaagc uuaccaugaa agccucugca gcacuucugu gucugcugcu cacagcagcu       60

gcuuucagcc cccaggggcu ugcucagcca guugggauua auacuucaac uaccugcugc      120

uacagauuua ucaauaagaa aaucccuaag cagaggcugg agagcuacag aaggaccacc      180

aguagccacu guccccggga agcuguaauc uucaagacca aacuggacaa ggagaucugu      240

gcugacccca cacagaagug gguccaggac uuuaugaagc accuggacaa gaaaacccaa      300

acuccaaagc ugugaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc      360

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc      480

ccccccccca aaggcucuuu ucagagccac cagaauu                               517


<210>  6022
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (wt)

<400>  6022
gggagaaagc uuaccaugcu gcucacucuu aucauucugu ugccaguagu uucaaaauuu       60

aguuuuguua gucucucagc accgcagcac uggagcuguc cugaagguac ucucgcagga      120

aauggcaauu cuacuugugu ggguccugca cccuucuuaa uuuucuccca uggaaauagu      180

aucuuuagga uugacacaga aggaaccaau uaugagcaau ugguggugga ugcugguguc      240

ucagugauca uggauuuuca uuauaaugag aaaagaaucu auugggugga uuuagaaaga      300

caacuuuugc aaagaguuuu ucugaauggg ucaaggcaag agagaguaug uaauauagag      360

aaaaauguuu cuggaauggc aauaaauugg auaaaugaag aaguuauuug gucaaaucaa      420

caggaaggaa ucauuacagu aacagauaug aaaggaaaua auucccacau ucuuuuaagu      480

gcuuuaaaau auccugcaaa uguagcaguu gauccaguag aaagguuuau auuuuggucu      540

ucagaggugg cuggaagccu uuauagagca gaucucgaug gugugggagu gaaggcucug      600

uuggagacau cagagaaaau aacagcugug ucauuggaug ugcuugauaa gcggcuguuu      660

uggauucagu acaacagaga aggaagcaau ucucuuauuu gcuccuguga uuaugaugga      720

gguucugucc acauuaguaa acauccaaca cagcauaauu uguuugcaau gucccuuuuu      780

ggugaccgua ucuucuauuc aacauggaaa augaagacaa uuuggauagc caacaaacac      840

acuggaaagg acaugguuag aauuaaccuc cauucaucau uuguaccacu uggugaacug      900

aaaguagugc auccacuugc acaacccaag gcagaagaug acacuuggga gccugagcag      960

aaacuuugca aauugaggaa aggaaacugc agcagcacug ugugugggca agaccuccag     1020

ucacacuugu gcaugugugc agagggauac gcccuaaguc gagaccggaa guacugugaa     1080

gauguuaaug aaugugcuuu uuggaaucau ggcuguacuc uuggguguaa aaacaccccu     1140

ggauccuauu acugcacgug cccuguagga uuuguucugc uuccugaugg gaaacgaugu     1200

caucaacuug uuuccugucc acgcaaugug ucugaaugca gccaugacug uguucugaca     1260

ucagaagguc ccuuauguuu cuguccugaa ggcucagugc uugagagaga ugggaaaaca     1320

uguagcgguu guuccucacc cgauaauggu ggauguagcc agcucugcgu uccucuuagc     1380

ccaguauccu gggaauguga uugcuuuccu ggguaugacc uacaacugga ugaaaaaagc     1440

ugugcagcuu caggaccaca accauuuuug cuguuugcca auucucaaga uauucgacac     1500

augcauuuug auggaacaga cuauggaacu cugcucagcc agcagauggg aaugguuuau     1560

gcccuagauc augacccugu ggaaaauaag auauacuuug cccauacagc ccugaagugg     1620

auagagagag cuaauaugga ugguucccag cgagaaaggc uuauugagga aggaguagau     1680

gugccagaag gucuugcugu ggacuggauu ggccguagau ucuauuggac agacagaggg     1740

aaaucucuga uuggaaggag ugauuuaaau gggaaacguu ccaaaauaau cacuaaggag     1800

aacaucucuc aaccacgagg aauugcuguu cauccaaugg ccaagagauu auucuggacu     1860

gauacaggga uuaauccacg aauugaaagu ucuucccucc aaggccuugg ccgucugguu     1920

auagccagcu cugaucuaau cuggcccagu ggaauaacga uugacuucuu aacugacaag     1980

uuguacuggu gcgaugccaa gcagucugug auugaaaugg ccaaucugga ugguucaaaa     2040

cgccgaagac uuacccagaa ugauguaggu cacccauuug cuguagcagu guuugaggau     2100

uauguguggu ucucagauug ggcuaugcca ucaguaauga gaguaaacaa gaggacuggc     2160

aaagauagag uacgucucca aggcagcaug cugaagcccu caucacuggu ugugguucau     2220

ccauuggcaa aaccaggagc agaucccugc uuauaucaaa acggaggcug ugaacauauu     2280

ugcaaaaaga ggcuuggaac ugcuuggugu ucgugucgug aagguuuuau gaaagccuca     2340

gaugggaaaa cgugucuggc ucuggauggu caucagcugu uggcaggagg ugaaguugau     2400

cuaaagaacc aaguaacacc auuggacauc uuguccaaga cuagaguguc agaagauaac     2460

auuacagaau cucaacacau gcuaguggcu gaaaucaugg ugucagauca agaugacugu     2520

gcuccugugg gaugcagcau guaugcucgg uguauuucag agggagagga ugccacaugu     2580

caguguuuga aaggauuugc uggggaugga aaacuauguu cugauauaga ugaaugugag     2640

augggugucc cagugugccc cccugccucc uccaagugca ucaacaccga aggugguuau     2700

gucugccggu gcucagaagg cuaccaagga gaugggauuc acugucuuga uauugaugag     2760

ugccaacugg gggagcacag cuguggagag aaugccagcu gcacaaauac agagggaggc     2820

uauaccugca ugugugcugg acgccugucu gaaccaggac ugauuugccc ugacucuacu     2880

ccacccccuc accucaggga agaugaccac cacuauuccg uaagaaauag ugacucugaa     2940

uguccccugu cccacgaugg guacugccuc caugauggug ugugcaugua uauugaagca     3000

uuggacaagu augcaugcaa cuguguuguu ggcuacaucg gggagcgaug ucaguaccga     3060

gaccugaagu ggugggaacu gcgccacgcu ggccacgggc agcagcagaa ggucaucgug     3120

guggcugucu gcgugguggu gcuugucaug cugcuccucc ugagccugug gggggcccac     3180

uacuacagga cucagaagcu gcuaucgaaa aacccaaaga auccuuauga ggagucgagc     3240

agagauguga ggagucgcag gccugcugac acugaggaug ggauguccuc uugcccucaa     3300

ccuugguuug ugguuauaaa agaacaccaa gaccucaaga auggggguca accaguggcu     3360

ggugaggaug gccaggcagc agauggguca augcaaccaa cuucauggag gcaggagccc     3420

caguuaugug gaaugggcac agagcaaggc ugcuggauuc caguauccag ugauaagggc     3480

uccugucccc agguaaugga gcggagcuuu cauaugcccu ccuaugggac acagacccuu     3540

gaagggggug ucgagaagcc ccauucucuc cuaucagcua acccauuaug gcaacaaagg     3600

gcccuggacc caccacacca aauggagcug acucagugag gacuaguuau aagacugacu     3660

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  6023
<211>  727
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (wt)

<400>  6023
gggagaaagc uuaccaugac cgcggggagg aggauggaga ugcucugugc cggcaggguc       60

ccugcgcugc ugcucugccu ggguuuccau cuucuacagg caguccucag uacaacugug      120

auuccaucau guaucccagg agaguccagu gauaacugca cagcuuuagu ucagacagaa      180

gacaauccac guguggcuca agugucaaua acaaagugua gcucugacau gaauggcuau      240

uguuugcaug gacagugcau cuaucuggug gacaugaguc aaaacuacug cagaugugaa      300

guggguuaua cugguguccg augugaacac uucuuuuuaa ccguccacca accuuuaagc      360

aaagaauaug uggcuuugac cgugauucuu auuauuuugu uucuuaucac agucgucggu      420

uccacauauu auuucugcag augguacaga aaucgaaaaa guaaagaacc aaagaaggaa      480

uaugagagag uuaccucagg ggauccagag uugccgcaag ucugaggacu aguuauaaga      540

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      720

cagaauu                                                                727


<210>  6024
<211>  1084
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (wt)

<400>  6024
gggagaaagc uuaccauggu gggugugggg gguggagaug uagaagaugu gacgccgcgg       60

cccggcgggu gccagauuag cggacgcggu gcccgcgguu gcaacgggau cccgggcgcu      120

gcagcuuggg aggcggcucu ccccaggcgg cguccgcgga gacacccauc cgugaacccc      180

aggucccggg ccgccggcuc gccgcgcacc aggggccggc ggacagaaga acggccgagc      240

ggcucgaggc ugggggaccg cgggcgcggc cgcgcgcugc cgggcgggag gcuggggggc      300

cggggccggg gccgugcccc ggagcggguc ggaggccggg gccggggccg ggggacggcg      360

gcuccccgcg cggcuccagc ggcucgggga ucccggccgg gccccgcagg gaccauggca      420

gccgggagca ucaccacgcu gcccgccuug cccgaggaug gcggcagcgg cgccuucccg      480

cccggccacu ucaaggaccc caagcggcug uacugcaaaa acgggggcuu cuuccugcgc      540

auccaccccg acggccgagu ugacgggguc cgggaaaaga gcgacccuca caucaagcua      600

caacuucaag cagaagagag aggaguugug ucuaucaaag gagugugugc uaaccguuac      660

cuggcuauga aggaagaugg aagauuacug gcuucuaaau guguuacgga ugaguguuuc      720

uuuuuugaac gauuggaauc uaauaacuac aauacuuacc ggucaaggaa auacaccagu      780

ugguaugugg cacugaaacg aacugggcag uauaaacuug gauccaaaac aggaccuggg      840

cagaaagcua uacuuuuucu uccaaugucu gcuaagagcu gaggacuagu uauaagacug      900

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1080

aauu                                                                  1084


<210>  6025
<211>  802
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (wt)

<400>  6025
gggagaaagc uuaccaugca caaauggaua cugacaugga uccugccaac uuugcucuac       60

agaucaugcu uucacauuau cugucuagug gguacuauau cuuuagcuug caaugacaug      120

acuccagagc aaauggcuac aaaugugaac uguuccagcc cugagcgaca cacaagaagu      180

uaugauuaca uggaaggagg ggauauaaga gugagaagac ucuucugucg aacacagugg      240

uaccugagga ucgauaaaag aggcaaagua aaagggaccc aagagaugaa gaauaauuac      300

aauaucaugg aaaucaggac aguggcaguu ggaauugugg caaucaaagg gguggaaagu      360

gaguucuauc uugcaaugaa caaggaagga aaacucuaug caaagaaaga augcaaugaa      420

gauuguaacu ucaaagaacu aauucuggaa aaccauuaca acacauaugc aucagcuaaa      480

uggacacaca acggagggga aauguuuguu gccuuaaauc aaaaggggau uccuguaaga      540

ggaaaaaaaa cgaagaaaga acaaaaaaca gcccacuuuc uuccuauggc aauaacuuaa      600

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu      660

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      780

ucuuuucaga gccaccagaa uu                                               802


<210>  6026
<211>  2404
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (wt)

<400>  6026
gggagaaagc uuaccaugug ggugaccaaa cuccugccag cccugcugcu gcagcauguc       60

cuccugcauc uccuccugcu ccccaucgcc auccccuaug cagagggaca aaggaaaaga      120

agaaauacaa uucaugaguu caaaaaauca gcaaagacua cccuaaucaa aauagaucca      180

gcacugaaga uaaaaaccaa aaaagugaau acugcagacc aaugugcuaa uagauguacu      240

aggaauaaag gacuuccauu cacuugcaag gcuuuuguuu uugauaaagc aagaaaacaa      300

ugccucuggu uccccuucaa uagcauguca aguggaguga aaaaagaauu uggccaugaa      360

uuugaccucu augaaaacaa agacuacauu agaaacugca ucauugguaa aggacgcagc      420

uacaagggaa caguaucuau cacuaagagu ggcaucaaau gucagcccug gaguuccaug      480

auaccacacg aacacagcuu uuugccuucg agcuaucggg guaaagaccu acaggaaaac      540

uacugucgaa auccucgagg ggaagaaggg ggacccuggu guuucacaag caauccagag      600

guacgcuacg aagucuguga cauuccucag uguucagaag uugaaugcau gaccugcaau      660

ggggagaguu aucgaggucu cauggaucau acagaaucag gcaagauuug ucagcgcugg      720

gaucaucaga caccacaccg gcacaaauuc uugccugaaa gauaucccga caagggcuuu      780

gaugauaauu auugccgcaa ucccgauggc cagccgaggc cauggugcua uacucuugac      840

ccucacaccc gcugggagua cugugcaauu aaaacaugcg cugacaauac uaugaaugac      900

acugauguuc cuuuggaaac aacugaaugc auccaagguc aaggagaagg cuacaggggc      960

acugucaaua ccauuuggaa uggaauccca ugucagcguu gggauucuca guauccucac     1020

gagcaugaca ugacuccuga aaauuucaag ugcaaggacc uacgagaaaa uuacugccga     1080

aauccagaug ggucugaauc acccuggugu uuuaccacug auccaaacau ccgaguuggc     1140

uacugcuccc aaauuccaaa cugugauaug ucacauggac aagauuguua ucgugggaau     1200

ggcaaaaauu auaugggcaa cuuaucccaa acaagaucug gacuaacaug uucaaugugg     1260

gacaagaaca uggaagacuu acaucgucau aucuucuggg aaccagaugc aaguaagcug     1320

aaugagaauu acugccgaaa uccagaugau gaugcucaug gacccuggug cuacacggga     1380

aauccacuca uuccuuggga uuauugcccu auuucucguu gugaagguga uaccacaccu     1440

acaauaguca auuuagacca ucccguaaua ucuugugcca aaacgaaaca auugcgaguu     1500

guaaauggga uuccaacacg aacaaacaua ggauggaugg uuaguuugag auacagaaau     1560

aaacauaucu gcggaggauc auugauaaag gagaguuggg uucuuacugc acgacagugu     1620

uucccuucuc gagacuugaa agauuaugaa gcauggcuug gaauccauga uguccacgga     1680

agaggagaug agaaaugcaa acagguucuc aauguuuccc agcugguaua uggcccugaa     1740

ggaucagauc ugguuuuaau gaagcuggcc aggccugcug uccuggauga uuuuguuagu     1800

acgauugauu uaccuaauua uggaugcaca auuccugaaa agaccaguug caguguuuau     1860

ggcuggggcu acacuggauu gaucaacuau gauggccuau uacgaguggc acaucucuau     1920

auaaugggaa augagaaaug cagccagcau caucgaggga aggugacucu gaaugagucu     1980

gaaauaugug cuggggcuga aaagauugga ucaggaccau gugaggggga uuaugguggc     2040

ccacuuguuu gugagcaaca uaaaaugaga augguucuug gugucauugu uccuggucgu     2100

ggaugugcca uuccaaaucg uccugguauu uuuguccgag uagcauauua ugcaaaaugg     2160

auacacaaaa uuauuuuaac auauaaggua ccacagucau agggacuagu uauaagacug     2220

acuagcccga ugggccuccc aacgggcccu ccuccccucc uugcaccgag auuaauaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     2400

aauu                                                                  2404


<210>  6027
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (wt)

<400>  6027
gggagaaagc uuaccauggc caaagccgcg gcgaucggca ucgaccuggg caccaccuac       60

uccugcgugg ggguguucca acacggcaag guggagauca ucgccaacga ccagggcaac      120

cgcaccaccc ccagcuacgu ggccuucacg gacaccgagc ggcucaucgg ggaugcggcc      180

aagaaccagg uggcgcugaa cccgcagaac accguguuug acgcgaagcg gcugauuggc      240

cgcaaguucg gcgacccggu ggugcagucg gacaugaagc acuggccuuu ccaggugauc      300

aacgacggag acaagcccaa ggugcagguc agcuacaagg gggagaccaa ggcauucuac      360

cccgaggaga ucucguccau ggugcugacc aagaugaagg agaucgccga ggcguaccug      420

ggcuacccgg ugaccaacgc ggugaucacc gugccggccu acuucaacga cucgcagcgc      480

caggccacca aggaugcggg ugugaucgcg gggcucaacg ugcugcggau caucaacgag      540

cccacggccg ccgccaucgc cuacggccug gacagaacgg gcaaggggga gcgcaacgug      600

cucaucuuug accugggcgg gggcaccuuc gacgugucca uccugacgau cgacgacggc      660

aucuucgagg ugaaggccac ggccggggac acccaccugg guggggagga cuuugacaac      720

aggcugguga accacuucgu ggaggaguuc aagagaaaac acaagaagga caucagccag      780

aacaagcgag ccgugaggcg gcugcgcacc gccugcgaga gggccaagag gacccugucg      840

uccagcaccc aggccagccu ggagaucgac ucccuguuug agggcaucga cuucuacacg      900

uccaucacca gggcgagguu cgaggagcug ugcuccgacc uguuccgaag cacccuggag      960

cccguggaga aggcucugcg cgacgccaag cuggacaagg cccagauuca cgaccugguc     1020

cuggucgggg gcuccacccg cauccccaag gugcagaagc ugcugcagga cuucuucaac     1080

gggcgcgacc ugaacaagag caucaacccc gacgaggcug uggccuacgg ggcggcggug     1140

caggcggcca uccugauggg ggacaagucc gagaacgugc aggaccugcu gcugcuggac     1200

guggcucccc ugucgcuggg gcuggagacg gccggaggcg ugaugacugc ccugaucaag     1260

cgcaacucca ccauccccac caagcagacg cagaucuuca ccaccuacuc cgacaaccaa     1320

cccggggugc ugauccaggu guacgagggc gagagggcca ugacgaaaga caacaaucug     1380

uuggggcgcu ucgagcugag cggcaucccu ccggccccca ggggcgugcc ccagaucgag     1440

gugaccuucg acaucgaugc caacggcauc cugaacguca cggccacgga caagagcacc     1500

ggcaaggcca acaagaucac caucaccaac gacaagggcc gccugagcaa ggaggagauc     1560

gagcgcaugg ugcaggaggc ggagaaguac aaagcggagg acgaggugca gcgcgagagg     1620

gugucagcca agaacgcccu ggaguccuac gccuucaaca ugaaaagcgc cguggaggau     1680

gaggggcuca agggcaagau cagcgaggcg gacaagaaga aggugcugga caagugucaa     1740

gaggucaucu cguggcugga cgccaacacc uuggccgaga aggacgaguu ugagcacaag     1800

aggaaggagc uggagcaggu cuguaacccc aucaucagcg gacuguacca gggugccggu     1860

ggucccgggc cugggggcuu cggggcucag ggucccaagg gagggucugg gucaggcccc     1920

accauugagg agguagauua gggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  6028
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (wt)

<400>  6028
gggagaaagc uuaccauggc caaagccgcg gcgaucggca ucgaccuggg caccaccuac       60

uccugcgugg ggguguucca acacggcaag guggagauca ucgccaacga ccagggcaac      120

cgcaccaccc ccagcuacgu ggccuucacg gacaccgagc ggcucaucgg ggaugcggcc      180

aagaaccagg uggcgcugaa cccgcagaac accguguuug acgcgaagcg gcugauuggc      240

cgcaaguucg gcgacccggu ggugcagucg gacaugaagc acuggccuuu ccaggugauc      300

aacgacggag acaagcccaa ggugcagguc agcuacaagg gggagaccaa ggcauucuac      360

cccgaggaga ucucguccau ggugcugacc aagaugaagg agaucgccga ggcguaccug      420

ggcuacccgg ugaccaacgc ggugaucacc gugccggccu acuucaacga cucgcagcgc      480

caggccacca aggaugcggg ugugaucgcg gggcucaacg ugcugcggau caucaacgag      540

cccacggccg ccgccaucgc cuacggccug gacagaacgg gcaaggggga gcgcaacgug      600

cucaucuuug accugggcgg gggcaccuuc gacgugucca uccugacgau cgacgacggc      660

aucuucgagg ugaaggccac ggccggggac acccaccugg guggggagga cuuugacaac      720

aggcugguga accacuucgu ggaggaguuc aagagaaaac acaagaagga caucagccag      780

aacaagcgag ccgugaggcg gcugcgcacc gccugcgaga gggccaagag gacccugucg      840

uccagcaccc aggccagccu ggagaucgac ucccuguuug agggcaucga cuucuacacg      900

uccaucacca gggcgagguu cgaggagcug ugcuccgacc uguuccgaag cacccuggag      960

cccguggaga aggcucugcg cgacgccaag cuggacaagg cccagauuca cgaccugguc     1020

cuggucgggg gcuccacccg cauccccaag gugcagaagc ugcugcagga cuucuucaac     1080

gggcgcgacc ugaacaagag caucaacccc gacgaggcug uggccuacgg ggcggcggug     1140

caggcggcca uccugauggg ggacaagucc gagaacgugc aggaccugcu gcugcuggac     1200

guggcucccc ugucgcuggg gcuggagacg gccggaggcg ugaugacugc ccugaucaag     1260

cgcaacucca ccauccccac caagcagacg cagaucuuca ccaccuacuc cgacaaccaa     1320

cccggggugc ugauccaggu guacgagggc gagagggcca ugacgaaaga caacaaucug     1380

uuggggcgcu ucgagcugag cggcaucccu ccggccccca ggggcgugcc ccagaucgag     1440

gugaccuucg acaucgaugc caacggcauc cugaacguca cggccacgga caagagcacc     1500

ggcaaggcca acaagaucac caucaccaac gacaagggcc gccugagcaa ggaggagauc     1560

gagcgcaugg ugcaggaggc ggagaaguac aaagcggagg acgaggugca gcgcgagagg     1620

gugucagcca agaacgcccu ggaguccuac gccuucaaca ugaaaagcgc cguggaggau     1680

gaggggcuca agggcaagau cagcgaggcg gacaagaaga agguucugga caagugucaa     1740

gaggucaucu cguggcugga cgccaacacc uuggccgaga aggacgaguu ugagcacaag     1800

aggaaggagc uggagcaggu cuguaacccc aucaucagcg gacuguacca gggugccggu     1860

ggucccgggc cuggcggcuu cggggcucag ggucccaagg gagggucugg gucaggcccu     1920

accauugagg agguggauua gggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  6029
<211>  2143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (wt)

<400>  6029
gggagaaagc uuaccauggc uacugccaag ggaaucgcca uaggcaucga ccugggcacc       60

accuacuccu gugugggggu guuccagcac ggcaaggugg agaucaucgc caacgaccag      120

ggcaaccgca ccacccccag cuacguggcc uucacagaca ccgagcggcu cauuggggau      180

gcggccaaga accagguagc aaugaauccc cagaacacug uuuuugaugc uaaacgucug      240

aucggcagga aauuuaauga uccuguugua caagcagaua ugaaacuuug gccuuuucaa      300

gugauuaaug aaggaggcaa gcccaaaguc cuuguguccu acaaagggga gaauaaagca      360

uucuacccug aggaaaucuc uucgauggua uugacuaagu ugaaggagac ugcugaggcc      420

uuuuugggcc acccugucac caaugcagug auuaccgugc cagccuauuu caaugacucu      480

caacgucagg cuacuaagga ugcaggagug auugcuggac uuaaugugcu aagaaucauc      540

aaugagccca cggcugcugc cauugccuau gguuuagaua aaggagguca aggagaacga      600

cauguccuga uuuuugaucu ggguggaggc acauuugaug ugucaauucu gaccauagau      660

gaugggauuu uugagguaaa ggccacugcu ggggacacuc accugggugg ggaggacuuu      720

gacaacaggc uugugagcca cuucguggag gaguucaaga ggaaacacaa aaaggacauc      780

agccagaaca agcgagccgu gaggcggcug cgcaccgccu gcgagagggc caagaggacc      840

cugucgucca gcacccaggc caaccuagaa auugauucac uuuaugaagg cauugacuuc      900

uauacaucca ucaccagagc ucgauuugaa gaguugugug cagaccuguu uagggguacc      960

cuggagccug uagaaaaagc gcuucgggau gccaagaugg auaaggcuaa aauccaugac     1020

auuguuuuag uagggggcuc cacccgcauc cccaaggugc agcggcugcu ucaggacuac     1080

uucaauggac gugaucucaa caagagcauc aacccugaug aggccguagc auauggggcu     1140

gcgguacaag cagccauccu gaugggggac aagucugaga agguacagga ccugcugcug     1200

cuggacgugg cuccccuguc ccuggggcug gagacggcug ggggcgugau gacugcccug     1260

auaaagcgca acuccaccau ccccaccaag cagacacaga uuuucaccac cuacucugac     1320

aaccaacccg gggugcugau ccagguguau gagggcgaga gggccaugac aaaggacaac     1380

aaccugcugg ggcgguuuga ccugacugga aucccuccag cacccagggg aguuccucag     1440

aucgagguga cguuugacau ugaugccaau gguauucuca augucacagc cacggacaag     1500

agcaccggca aggugaacaa gaucaccauc accaaugaca agggccgccu gagcaaggag     1560

gagauugagc gcaugguucu ggaugcugag aaauauaaag cugaagauga gguccagagg     1620

gagaaaauug cugcaaagaa ugccuuagaa uccuaugcuu uuaacaugaa gaguguugug     1680

agugaugaag guuugaaggg caagauuagu gagucugaua aaaauaaaau auuggauaaa     1740

ugcaacgagc uccuuucgug gcuggagguc aaucaacugg cagagaaaga ugaguuugau     1800

cauaagagaa aggaauugga gcagaugugu aacccuauca ucacaaaacu cuaccaagga     1860

ggaugcacug ggccugccug cggaacaggg uaugugccug gaaggccugc cacaggcccc     1920

acaauugaag aaguagauua aggacuaguu auaagacuga cuagcccgau gggccuccca     1980

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2100

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2143


<210>  6030
<211>  2740
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (wt)

<400>  6030
gggagaaagc uuaccauguc gguggugggc auagaccugg gcuuccagag cugcuacguc       60

gcuguggccc gcgccggcgg caucgagacu aucgcuaaug aguauagcga ccgcugcacg      120

ccggcuugca uuucuuuugg uccuaagaau cguucaauug gagcagcagc uaaaagccag      180

guaauuucua augcaaagaa cacaguccaa ggauuuaaaa gauuccaugg ccgagcauuc      240

ucugauccau uuguggaggc agaaaaaucu aaccuugcau augauauugu gcaguugccu      300

acaggauuaa cagguauaaa ggugacauau auggaggaag aacgaaauuu uaccacugag      360

caagugacug ccaugcuuuu guccaaacug aaggagacag ccgaaagugu ucuuaagaag      420

ccuguaguug acuguguugu uucgguuccu uguuucuaua cugaugcaga aagacgauca      480

gugauggaug caacacagau ugcuggucuu aauugcuugc gauuaaugaa ugaaaccacu      540

gcaguugcuc uugcauaugg aaucuauaag caggaucuuc cugccuuaga agagaaacca      600

agaaauguag uuuuuguaga caugggccac ucugcuuauc aaguuucugu augugcauuu      660

aauagaggaa aacugaaagu ucuggccacu gcauuugaca cgacauuggg agguagaaaa      720

uuugaugaag uguuaguaaa ucacuucugu gaagaauuug ggaagaaaua caagcuagac      780

auuaagucca aaauccgugc auuauuacga cucucucagg agugugagaa acucaagaaa      840

uugaugagug caaaugcuuc agaucucccu uugagcauug aauguuuuau gaaugauguu      900

gauguaucug gaacuaugaa uagaggcaaa uuucuggaga ugugcaauga ucucuuagcu      960

agaguggagc caccacuucg uaguguuuug gaacaaacca aguuaaagaa agaagauauu     1020

uaugcagugg agauaguugg uggugcuaca cgaaucccug cgguaaaaga gaagaucagc     1080

aaauuuuucg guaaagaacu uaguacaaca uuaaaugcug augaagcugu cacucgaggc     1140

ugugcauugc agugugccau cuuaucgccu gcuuucaaag ucagagaauu uucuaucacu     1200

gauguaguac cauauccaau aucucugaga uggaacucuc cagcugaaga agggucaagu     1260

gacugugaag ucuuuuccaa aaaucaugcu gcuccuuucu cuaaaguucu uacauuuuau     1320

agaaaggaac cuuucacucu ugaggccuac uacagcucuc cucaggauuu gcccuaucca     1380

gauccugcua uagcucaguu uucaguucag aaagucacuc cucagucuga uggcuccagu     1440

ucaaaaguga aagucaaagu ucgaguaaau guccauggca uuuucagugu guccagugca     1500

ucuuuagugg agguucacaa gucugaggaa aaugaggagc caauggaaac agaucagaau     1560

gcaaaggagg aagagaagau gcaaguggac caggaggaac cacauguuga agaacaacag     1620

cagcagacac cagcagaaaa uaaggcagag ucugaagaaa uggagaccuc ucaagcugga     1680

uccaaggaua aaaagaugga ccaaccaccc caagccaaga aggcaaaagu gaagaccagu     1740

acuguggacc ugccaaucga gaaucagcua uuauggcaga uagacagaga gaugcucaac     1800

uuguacauug aaaaugaggg uaagaugauc augcaggaua aacuggagaa ggagcggaau     1860

gaugcuaaga acgcagugga ggaauaugug uaugaaauga gagacaagcu gaguggugaa     1920

uaugagaagu uugugaguga agaugaucgu aacaguuuua cuuugaaacu ggaagauacu     1980

gaaaauuggu uguaugagga uggagaagac cagccaaagc aaguuuaugu ugauaaguug     2040

gcugaauuaa aaaaucuagg ucaaccuauu aagauacguu uccaggaauc ugaagaacga     2100

ccaaaauuau uugaagaacu agggaaacag auccaacagu auaugaaaau aaucagcucu     2160

uucaaaaaca aggaggacca guaugaucau uuggaugcug cugacaugac aaagguagaa     2220

aaaagcacaa augaagcaau ggaguggaug aauaacaagc uaaaucugca gaacaagcag     2280

aguuugacca uggauccagu ugucaaguca aaagagauug aagcuaaaau uaaggagcug     2340

acaaguacuu guagcccuau aauuucaaag cccaaaccca aaguggaacc uccaaaagag     2400

gaacaaaaaa augcagagca gaauggacca guggauggac aaggagacaa cccaggcccc     2460

caggcugcug agcaggguac agacacagcu gugccuucgg auucagacaa gaagcugccu     2520

gaaauggaca uugauugagg acuaguuaua agacugacua gcccgauggg ccucccaacg     2580

ggcccuccuc cccuccuugc accgagauua auaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     2700

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           2740


<210>  6031
<211>  2737
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (wt)

<400>  6031
gggagaaagc uuaccauguc ugugguuggc auugaccucg gcuuucucaa cugcuacauu       60

gcugucgcga gaaguggcgg caucgagacc aucgccaaug aguacagcga cagguguacc      120

ccggccugua uaucauuggg aucaagaacu cgagccauug gaaaugcagc aaagagccag      180

auagucacga acguaagaaa uacaauucau ggcuucaaaa agcugcaugg gcgaucauuu      240

gaugauccca uugugcaaac ugaaaggauc aggcuucccu augaacugca gaaaaugccu      300

aauggaagug caggaguuaa ggugcgguac uuagaggaag agagaccuuu ugcaauugag      360

caaguuacug gaaugcuguu agccaagcug aaagagacuu cagaaaaugc uuugaagaaa      420

ccaguggcug acugugugau uucaauuccu agcuuuuuua cugaugccga gagaagaucu      480

gugauggcug cagcccaggu ugcaggcuua aauuguuuaa gguugaugaa ugaaacuacu      540

gcaguugcac uggcguaugg aauuuauaaa caggaucuuc ccccauuaga ugagaaacca      600

agaaauguag uauuuauuga uaugggacau ucugccuauc aggucuuggu uugugcuuuu      660

aacaaaggaa aacuuaaagu cuuggcuacu accuuugauc cauauuuggg uggcaggaac      720

uuugaugagg cuuuaguaga cuacuucugu gaugaguuca agaccaaaua uaagauaaau      780

gugaaagaaa acucucgggc cuuguugcgu uuauaucagg aaugugaaaa acuaaagaag      840

cuaaugagug caaaugcauc agaucuucca uugaacauug aguguuucau gaaugaccuu      900

gauguuucua guaaaaugaa cagggcucaa uuugaacaac ugugugcuuc ccuuuuggcc      960

aggguugaac caccuuuaaa agcaguaaug gaacaagcua acuuacaacg ugaagacauu     1020

aguaguauag aaauuguagg aggagcaaca cgaaucccug cagugaaaga acaaaucacu     1080

aaauucuuuc uuaaagacau aaguaccaca uuaaaugcug augaagcugu ugcaagagga     1140

ugugcguuac agugugcgau ucucucacca gcauuuaaag ugcgugaauu uuccauaaca     1200

gaccuuguuc ccuauucaau cacauuaagg uggaagaccu cuuuugaaga uggaaguggg     1260

gaaugugaag uuuucuguaa gaaccauccu gccccauucu caaaagucau uacuuuccac     1320

aagaaggaac cauuugaacu agaagcauuu uauacuaauu uacaugaagu gccuuauccu     1380

gaugcaagaa uugggagcuu cacuauucag aauguuuuuc cacagucuga uggugauagu     1440

uccaaaguga agguuaaagu ucguguuaac auccauggaa ucuucagugu ggcuagcgca     1500

ucaguaauug agaagcaaaa uuuggaaggc gaucacagug augcuccaau ggagacagaa     1560

acuucauuua aaaaugaaaa caaagauaau auggauaaaa ugcagguuga ucaagaagaa     1620

gggcaucaaa aaugucaugc ugaacacacu ccagaagagg aaauugauca uacaggagcc     1680

aaaacaaagu cagcugucuc agacaaacaa gaccgauuaa aucagacacu uaaaaaagga     1740

aaagucaaaa guauugaucu accgauccag aguagccuau guagacaacu aggccaagau     1800

cuucucaaca gcuacauuga aaaugagggg aagaugauca ugcaagauaa guuagagaaa     1860

gaaagaaaug augcuaagaa ugccguugaa gaauauguau augauuuuag agacaggcug     1920

ggcacugucu augaaaaauu caucacucca gaagacuuga guaaacuguc ugcaguauug     1980

gaagacacag aaaauuggcu uuaugaagac ggagaggacc aaccuaaaca aguuuaugug     2040

gauaagcugc aagaacuaaa gaaauacggc cagccuauuc aaaugaagua cauggagcau     2100

gaagagagac caaaagccuu aaaugacuug ggaaaaaaga uccaacuugu caugaaagug     2160

auagaagcau auagaaacaa ggaugaaaga uaugaucauc uggauccuac ugaaauggaa     2220

aagguugaaa aauguaucag ugaugccaug aguuggcuga auaguaagau gaaugcacag     2280

aacaaacuaa gucucacuca agauccugug guaaaaguuu cagaaauagu agcaaaguca     2340

aaggaacugg auaauuucug uaaccccauc auuuacaagc ccaaaccaaa agcagaaguu     2400

ccugaagaca aaccaaaagc uaauagugaa cacaauggcc caauggaugg acagagugga     2460

acugaaacua aaucagauuc aacaaaagac agcucacagc auacuaaauc cucuggagag     2520

auggaagugg acuaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2580

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2640

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2700

ccccccccca aaggcucuuu ucagagccac cagaauu                              2737


<210>  6032
<211>  2182
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (wt)

<400>  6032
gggagaaagc uuaccaugaa gcucucccug guggccgcga ugcugcugcu gcucagcgcg       60

gcgcgggccg aggaggagga caagaaggag gacgugggca cgguggucgg caucgaccug      120

gggaccaccu acuccugcgu cggcguguuc aagaacggcc gcguggagau caucgccaac      180

gaucagggca accgcaucac gccguccuau gucgccuuca cuccugaagg ggaacgucug      240

auuggcgaug ccgccaagaa ccagcucacc uccaaccccg agaacacggu cuuugacgcc      300

aagcggcuca ucggccgcac guggaaugac ccgucugugc agcaggacau caaguucuug      360

ccguucaagg ugguugaaaa gaaaacuaaa ccauacauuc aaguugauau uggagguggg      420

caaacaaaga cauuugcucc ugaagaaauu ucugccaugg uucucacuaa aaugaaagaa      480

accgcugagg cuuauuuggg aaagaagguu acccaugcag uuguuacugu accagccuau      540

uuuaaugaug cccaacgcca agcaaccaaa gacgcuggaa cuauugcugg ccuaaauguu      600

augaggauca ucaacgagcc uacggcagcu gcuauugcuu auggccugga uaagagggag      660

ggggagaaga acauccuggu guuugaccug gguggcggaa ccuucgaugu gucucuucuc      720

accauugaca auggugucuu cgaaguugug gccacuaaug gagauacuca ucugggugga      780

gaagacuuug accagcgugu cauggaacac uucaucaaac uguacaaaaa gaagacgggc      840

aaagauguca ggaaagacaa uagagcugug cagaaacucc ggcgcgaggu agaaaaggcc      900

aaacgggccc ugucuucuca gcaucaagca agaauugaaa uugaguccuu cuaugaagga      960

gaagacuuuu cugagacccu gacucgggcc aaauuugaag aacucaacau ggaucuguuc     1020

cggucuacua ugaagcccgu ccagaaagug uuggaagauu cugauuugaa gaagucugau     1080

auugaugaaa uuguucuugu ugguggcucg acucgaaucc caaagauuca gcaacugguu     1140

aaagaguucu ucaauggcaa ggaaccaucc cguggcauaa acccagauga agcuguagcg     1200

uauggugcug cuguccaggc uggugugcuc ucuggugauc aagauacagg ugaccuggua     1260

cugcuugaug uauguccccu uacacuuggu auugaaacug ugggaggugu caugaccaaa     1320

cugauuccaa ggaacacagu ggugccuacc aagaagucuc agaucuuuuc uacagcuucu     1380

gauaaucaac caacuguuac aaucaagguc uaugaaggug aaagaccccu gacaaaagac     1440

aaucaucuuc uggguacauu ugaucugacu ggaaucccuc cugcuccucg ugggguccca     1500

cagauugaag ucaccuuuga gauagaugug aaugguauuc uucgagugac agcugaagac     1560

aaggguacag ggaacaaaaa uaagaucaca aucaccaaug accagaaucg ccugacaccu     1620

gaagaaaucg aaaggauggu uaaugaugcu gagaaguuug cugaggaaga caaaaagcuc     1680

aaggagcgca uugauacuag aaaugaguug gaaagcuaug ccuauucucu aaagaaucag     1740

auuggagaua aagaaaagcu gggagguaaa cuuuccucug aagauaagga gaccauggaa     1800

aaagcuguag aagaaaagau ugaauggcug gaaagccacc aagaugcuga cauugaagac     1860

uucaaagcua agaagaagga acuggaagaa auuguucaac caauuaucag caaacucuau     1920

ggaagugcag gcccuccccc aacuggugaa gaggauacag cagaaaaaga ugaguuguag     1980

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     2040

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2160

ucuuuucaga gccaccagaa uu                                              2182


<210>  6033
<211>  2149
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (wt)

<400>  6033
gggagaaagc uuaccaugca ggccccacgg gagcucgcgg ugggcaucga ccugggcacc       60

accuacucgu gcgugggcgu guuucagcag ggccgcgugg agauccuggc caacgaccag      120

ggcaaccgca ccacgcccag cuacguggcc uucaccgaca ccgagcggcu ggucggggac      180

gcggccaaga gccaggcggc ccugaacccc cacaacaccg uguucgaugc caagcggcug      240

aucgggcgca aguucgcgga caccacggug cagucggaca ugaagcacug gcccuuccgg      300

guggugagcg agggcggcaa gcccaaggug cgcguaugcu accgcgggga ggacaagacg      360

uucuaccccg aggagaucuc guccauggug cugagcaaga ugaaggagac ggccgaggcg      420

uaccugggcc agcccgugaa gcacgcagug aucaccgugc ccgccuauuu caaugacucg      480

cagcgccagg ccaccaagga cgcgggggcc aucgcggggc ucaacguguu gcggaucauc      540

aaugagccca cggcagcugc caucgccuau gggcuggacc ggcggggcgc gggagagcgc      600

aacgugcuca uuuuugaccu gggugggggc accuucgaug ugucgguucu cuccauugac      660

gcuggugucu uugaggugaa agccacugcu ggagauaccc accugggagg agaggacuuc      720

gacaaccggc ucgugaacca cuucauggaa gaguuccggc ggaagcaugg gaaggaccug      780

agcgggaaca agcgugcccu gcgcaggcug cgcacagccu gugagcgcgc caagcgcacc      840

cuguccucca gcacccaggc cacccuggag auagacuccc uguucgaggg cguggacuuc      900

uacacgucca ucacucgugc ccgcuuugag gaacugugcu cagaccucuu ccgcagcacc      960

cuggagccgg uggagaaggc ccugcgggau gccaagcugg acaaggccca gauucaugac     1020

gucguccugg uggggggcuc cacacgcauc cccaaggugc agaaguugcu gcaggacuuc     1080

uucaacggca aggagcugaa caagagcauc aacccugaug aggcuguggc cuauggggcu     1140

gcugugcagg cggccguguu gaugggggac aaaugugaga aagugcagga ucuccugcug     1200

cuggaugugg cuccccuguc ucuggggcug gagacagcag gaggggugau gaccacgcug     1260

auccagagga acgccacuau ccccaccaag cagacccaga cuuucaccac cuacucggac     1320

aaccagccug gggucuucau ccagguguau gagggugaga gggccaugac caaggacaac     1380

aaccugcugg ggcguuuuga acucaguggc aucccuccug ccccacgugg agucccccag     1440

auagagguga cuuuugacau ugaugcuaau ggcauccuga gcgugacagc cacugacagg     1500

agcacaggua aggcuaacaa gaucaccauc accaaugaca agggccggcu gagcaaggag     1560

gagguggaga ggaugguuca ugaagccgag caguacaagg cugaggauga ggcccagagg     1620

gacagagugg cugccaaaaa cucgcuggag gcccaugucu uccaugugaa agguucuuug     1680

caagaggaaa gccuuaggga caagauuccc gaagaggaca ggcgcaaaau gcaagacaag     1740

ugucgggaag uccuugccug gcuggagcac aaccagcugg cagagaagga ggaguaugag     1800

caucagaaga gggagcugga gcaaaucugu cgccccaucu ucuccaggcu cuaugggggg     1860

ccuggugucc cugggggcag caguuguggc acucaagccc gccaggggga ccccagcacc     1920

ggccccauca uugaggaggu ugauugagga cuaguuauaa gacugacuag cccgaugggc     1980

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2100

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2149


<210>  6034
<211>  1321
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (wt)

<400>  6034
gggagaaagc uuaccaugca ggccccacgg gagcucgcgg ugggcaucga ccugggcacc       60

accuacucgu gcgugggcgu guuucagcag ggccgcgugg agauccuggc caacgaccag      120

ggcaaccgca ccacgcccag cuacguggcc uucaccgaca ccgagcggcu ggucggggac      180

gcggccaaga gccaggcggc ccugaacccc cacaacaccg uguucgaugc caagcggcug      240

aucgggcgca aguucgcgga caccacggug cagucggaca ugaagcacug gcccuuccag      300

guggugagcg agggcggcaa gcccaaggug cgcguaugcu accgcgggga ggacaagacg      360

uucuaccccg aggagaucuc guccauggug cugagcaaga ugaaggagac ggccgaggcg      420

uaccugggcc agcccgugaa gcacgcagug aucaccgugc ccaccuauuu caguaacucg      480

cagcgccagg ccaccaagga cgcgggggcc aucgcggggc ucaaggugcu gccgaucauc      540

aaugaggcca cggcagcagc caucgccuau gggcuggacc ggcggggcgc gggaaagcgc      600

aacgugcuca uuuuugaccu gggugggggc accuucgaug ugucgguucu cuccauugac      660

gccggugucu uugaggugaa agccacugcu ggagauaccc accugggagg agaggacuuc      720

gacaaccggc ucgugaacca cuucauggaa gaguuccggc ggaagcaugg gaaggaccug      780

agcgggaaca agcgugcccu gcgcaggcug cgcacagccu gugagcgcgc caagcgcacc      840

ccguccucca gcacccaggc cacccuggag auagacuccc uguucgaggg cguggacuuc      900

uacaagucca ucacucgugc ccgcuuugag gaacugugcu cagaccucuu ccgcagcacc      960

cuggagccgg uggagaaggc ccugcgggau gccaagcugg acaaggccca gauucaugac     1020

uucguccugg ggggagggcu ccacucgcau ccccaaggug cagaaguugc ugcaggacuu     1080

cuucaacggc aaggagcuga acaagagcau caacccugag gacuaguuau aagacugacu     1140

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1260

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1320

u                                                                     1321


<210>  6035
<211>  2158
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (wt)

<400>  6035
gggagaaagc uuaccauguc caagggaccu gcaguuggua uugaucuugg caccaccuac       60

ucuugugugg guguuuucca gcacggaaaa gucgagauaa uugccaauga ucagggaaac      120

cgaaccacuc caagcuaugu cgccuuuacg gacacugaac gguugaucgg ugaugccgca      180

aagaaucaag uugcaaugaa ccccaccaac acaguuuuug augccaaacg ucugauugga      240

cgcagauuug augaugcugu uguccagucu gauaugaaac auuggcccuu uaugguggug      300

aaugaugcug gcaggcccaa gguccaagua gaauacaagg gagagaccaa gagcuucuau      360

ccagaggagg ugucuucuau gguucugaca aagaugaagg aaauugcaga agccuaccuu      420

gggaagacug uuaccaaugc uguggucaca gugccagcuu acuuuaauga cucucagcgu      480

caggcuacca aagaugcugg aacuauugcu ggucucaaug uacuuagaau uauuaaugag      540

ccaacugcug cugcuauugc uuacggcuua gacaaaaagg uuggagcaga aagaaacgug      600

cucaucuuug accugggagg uggcacuuuu gaugugucaa uccucacuau ugaggaugga      660

aucuuugagg ucaagucuac agcuggagac acccacuugg guggagaaga uuuugacaac      720

cgaaugguca accauuuuau ugcugaguuu aagcgcaagc auaagaagga caucagugag      780

aacaagagag cuguaagacg ccuccguacu gcuugugaac gugcuaagcg uacccucucu      840

uccagcaccc aggccaguau ugagaucgau ucucucuaug aaggaaucga cuucuauacc      900

uccauuaccc gugcccgauu ugaagaacug aaugcugacc uguuccgugg cacccuggac      960

ccaguagaga aagcccuucg agaugccaaa cuagacaagu cacagauuca ugauauuguc     1020

cugguuggug guucuacucg uauccccaag auucagaagc ugcuccaaga cuucuucaau     1080

ggaaaagaac ugaauaagag caucaacccu gaugaagcug uugcuuaugg ugcagcuguc     1140

caggcagcca ucuugucugg agacaagucu gagaauguuc aagauuugcu gcucuuggau     1200

gucacuccuc uuucccuugg uauugaaacu gcugguggag ucaugacugu ccucaucaag     1260

cguaauacca ccauuccuac caagcagaca cagaccuuca cuaccuauuc ugacaaccag     1320

ccuggugugc uuauucaggu uuaugaaggc gagcgugcca ugacaaagga uaacaaccug     1380

cuuggcaagu uugaacucac aggcauaccu ccugcacccc gagguguucc ucagauugaa     1440

gucacuuuug acauugaugc caaugguaua cucaaugucu cugcugugga caagaguacg     1500

ggaaaagaga acaagauuac uaucacuaau gacaagggcc guuugagcaa ggaagacauu     1560

gaacguaugg uccaggaagc ugagaaguac aaagcugaag augagaagca gagggacaag     1620

gugucaucca agaacucacu ugaguccuau gccuucaaca ugaaagcaac uguugaagau     1680

gagaaacuuc aaggcaagau uaacgaugag gacaaacaga agauucugga caaguguaau     1740

gaaauuauca acuggcuuga uaagaaucag acugcugaga aggaagaauu ugaacaucaa     1800

cagaaagagc uggagaaagu uugcaacccc aucaucacca agcuguacca gagugcagga     1860

ggcaugccag gaggaaugcc ugggggauuu ccugguggug gagcuccucc cucugguggu     1920

gcuuccucag ggcccaccau ugaagagguu gauuaaggac uaguuauaag acugacuagc     1980

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2040

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2100

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2158


<210>  6036
<211>  2257
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (wt)

<400>  6036
gggagaaagc uuaccaugau aagugccagc cgagcugcag cagcccgucu cgugggcgcc       60

gcagccuccc ggggcccuac ggccgcccgc caccaggaua gcuggaaugg ccuuagucau      120

gaggcuuuua gacuuguuuc aaggcgggau uaugcaucag aagcaaucaa gggagcaguu      180

guugguauug auuuggguac uaccaacucc ugcguggcag uuauggaagg uaaacaagca      240

aaggugcugg agaaugccga aggugccaga accaccccuu caguuguggc cuuuacagca      300

gauggugagc gacuuguugg aaugccggcc aagcgacagg cugucaccaa cccaaacaau      360

acauuuuaug cuaccaagcg ucucauuggc cggcgauaug augauccuga aguacagaaa      420

gacauuaaaa auguucccuu uaaaauuguc cgugccucca auggugaugc cuggguugag      480

gcucauggga aauuguauuc uccgagucag auuggagcau uuguguugau gaagaugaaa      540

gagacugcag aaaauuacuu ggggcacaca gcaaaaaaug cugugaucac agucccagcu      600

uauuucaaug acucgcagag acaggccacu aaagaugcug gccagauauc uggacugaau      660

gugcuucggg ugauuaauga gcccacagcu gcugcucuug ccuauggucu agacaaauca      720

gaagacaaag ucauugcugu auaugauuua ggugguggaa cuuuugauau uucuauccug      780

gaaauucaga aaggaguauu ugaggugaaa uccacaaaug gggauaccuu cuuagguggg      840

gaagacuuug accaggccuu gcuacggcac auugugaagg aguucaagag agagacaggg      900

guugauuuga cuaaagacaa cauggcacuu cagaggguac gggaagcugc ugaaaaggcu      960

aaaugugaac ucuccucauc ugugcagacu gacaucaauu ugcccuaucu uacaauggau     1020

ucuucuggac ccaagcauuu gaauaugaag uugacccgug cucaauuuga agggauuguc     1080

acugaucuaa ucagaaggac uaucgcucca ugccaaaaag cuaugcaaga ugcagaaguc     1140

agcaagagug acauaggaga agugauucuu guggguggca ugacuaggau gcccaagguu     1200

cagcagacug uacaggaucu uuuuggcaga gccccaagua aagcugucaa uccugaugag     1260

gcuguggcca uuggagcugc cauucaggga gguguguugg ccggcgaugu cacggaugug     1320

cugcuccuug augucacucc ccugucucug gguauugaaa cucuaggagg ugucuuuacc     1380

aaacuuauua auaggaauac cacuauucca accaagaaaa gccagguauu cucuacugcc     1440

gcugaugguc aaacgcaagu ggaaauuaaa gugugucagg gugaaagaga gauggcugga     1500

gacaacaaac uccuuggaca guuuacuuug auuggaaucc caccagcccc ucguggaguu     1560

ccucagauug aaguuacauu ugacauugau gccaauggga uaguacaugu uucugcuaaa     1620

gauaaaggca caggacguga gcagcagauu guaauccagu cuucuggugg auuaagcaaa     1680

gaugauauug aaaauauggu uaaaaaugca gagaaauaug cugaagaaga ccggcgaaag     1740

aaggaacgag uugaagcagu uaauauggcu gaaggaauca uucacgacac agaaaccaag     1800

auggaagagu ucaaggacca auuaccugcu gaugagugca acaagcugaa agaagagauu     1860

uccaaaauga gggagcuccu ggcuagaaaa gacagcgaaa caggagaaaa uauuagacag     1920

gcagcauccu cucuucagca ggcaucacug aagcuguucg aaauggcaua caaaaagaug     1980

gcaucugagc gagaaggcuc uggaaguucu ggcacugggg aacaaaagga agaucaaaag     2040

gaggaaaaac aguaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     2100

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2220

ccccccccca aaggcucuuu ucagagccac cagaauu                              2257


<210>  6037
<211>  2278
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (wt)

<400>  6037
gggagaaagc uuaccauguu ggcugucccg gagaugggcc ugcaggggcu guacaucggc       60

uccagcccgg agcggucccc agugccuagc ccacccggcu ccccgaggac ccaggaaagc      120

ugcggcauug ccccccucac acccucgcag ucuccaaaac ccgagguccg agccccccag      180

caggccuccu ucucuguggu gguggccauu gacuucggca ccacgucuag uggcuaugcu      240

uucagcuuug ccagugaccc ugaggccauc cacaugauga ggaaauggga gggcggagac      300

ccgggcgugg cccaccagaa gaccccgacc ugccugcugc ugacuccgga gggcgccuuc      360

cacagcuuug gcuacaccgc ccgcgauuac uaccaugacc uggaccccga agaggcgcgg      420

gacuggcucu acuucgagaa guucaagaug aagauccaca gcgccacgga ucucaccuug      480

aagacccagc uagaggcagu aaauggaaag acgaugcccg cccuggaggu guucgcccau      540

gcccugcgcu ucuucaggga gcacgcccuu caggagcuga gggagcagag cccaucgcug      600

ccagagaagg acacugugcg cuggguguug acggugccug ccaucuggaa acagccagcc      660

aagcaguuca ugcgggaggc ugccuaccug gcuggacuug ugucccgaga gaaugcagag      720

cagcuacuca ucgcccugga gcccgaggcc gccucgguau acugccgcaa gcugcgccug      780

caccagcucc uggaccugag uggccgggcc ccagguggug ggcgccuggg ugagcgccgc      840

uccaucgacu ccagcuuccg ucaggcucgg gagcagcugc gaaggucccg ccacagccgc      900

acguuccugg uggagucagg cguaggagag cugugggcag agaugcaagc aggagaccgc      960

uacguggugg ccgacugcgg cggaggcacc guggaccuga cggugcacca gcuggagcag     1020

ccccauggca cccucaagga gcucuacaag gcaucugggg gcccuuaugg cgcggugggc     1080

guggaccugg ccuucgagca gcugcugugc cgcaucuucg gcgaggacuu caucgccacc     1140

uucaaaaggc aacggccggc agccugggua gaucugacca ucgccuucga ggcucgcaag     1200

cgcacugcug gcccacaccg ugcaggggcg cucaacaucu cgcugcccuu cuccuucauu     1260

gacuucuacc gcaagcagcg gggccacaac guggagaccg cucugcgcag gagcagcgug     1320

aacuucguga agugguccuc acaggggaug cuccgaaugu cuugugaagc caugaacgag     1380

cucuuucagc ccaccgucag cgggaucauc cagcacauag aggcccugcu ggcacggccg     1440

gaggugcagg gugugaagcu gcuguuccua gugggcggcu ucgccgaguc agcggugcug     1500

cagcacgcgg ugcaggcggc gcugggcgcc cgcggucugc gugucguggu cccgcacgac     1560

gugggccuca ccauccucaa aggcgcggug cuguucggcc aggcgccggg cguggugcgg     1620

guccgccgcu cgccgcucac cuauggcgug ggcgugcuca accgcuuugu gccugggcgc     1680

cacccgcccg aaaagcugcu gguucgcgac ggccgccgcu ggugcaccga cgucuucgag     1740

cgcuucgugg ccgccgagca gucgguggcc cugggcgagg aggugcggcg cagcuacugc     1800

ccggcgcguc ccggccagcg gcgcguacuc aucaaccugu acugcugcgc ggcagaggau     1860

gcgcgcuuca ucaccgaccc cggcgugcgc aaaugcggcg cgcucagccu cgagcuugag     1920

cccgccgacu gcggccagga caccgccggc gcgccucccg gccgccgcga gauccgcgcc     1980

gccaugcagu uuggcgacac cgaaauuaag gucaccgccg ucgacgucag caccaaucgc     2040

uccgugcgcg cguccaucga cuuucuuucc aacugaggac uaguuauaag acugacuagc     2100

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     2220

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       2278


<210>  6038
<211>  1747
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (wt)

<400>  6038
gggagaaagc uuaccauggc ggccaucgga guucaccugg gcugcaccuc agccugugug       60

gccgucuaua aggauggccg ggcuggugug guugcaaaug augccgguga ccgaguuacu      120

ccagcuguug uugcuuacuc agaaaaugaa gagauuguug gauuggcagc aaaacaaagu      180

agaauaagaa auauuucaaa uacaguaaug aaaguaaagc agauccuggg cagaagcucc      240

agugauccac aagcucagaa auacaucgcg gaaaguaaau guuuagucau ugaaaaaaau      300

gggaaauuac gauaugaaau agauacugga gaagaaacaa aauuuguuaa cccagaagau      360

guugccagac ugauauuuag uaaaaugaaa gaaacggcac auucuguauu gggcucagau      420

gcaaaugaug uaguuauuac ugucccguuu gauuuuggag aaaagcaaaa aaaugcucuu      480

ggagaagcag cuagagcugc uggauuuaau guuuugcgau uaauucacga accgucugca      540

gcucugcuug cuuauggaau uggacaagac uccccuacug gaaaaagcaa uauuuuggug      600

uuuaagcugg gaggaacauc cuuaucucuc agcgucaugg aaguuaacag uggaauauau      660

cggguucuuu caacaaacac ugaugauaac aucgguggug cacauuucac agaaaccuua      720

gcacaguauc uagcuucuga guuccaaaga uccuucaaac augaugugag aggaaaugcg      780

cgagccauga ugaaauuaac gaacagugcu gaaguagcga aacauucuuu gucaaccuug      840

ggaagugcca acuguuuucu ugacucauua uaugaagguc aagauuuuga uugcaaugug      900

uccagagcaa gauuugaacu ucuuuguucu ccacuuuuua auaaguguau agaagcaauc      960

agaggacucu uagaucaaaa uggauuuaca gcagaugaua ucaacaaggu uguccuuugu     1020

ggagggucuu cucgaauccc aaagcuacag caacugauua aagaucuuuu cccagcuguu     1080

gagcuucuca auucuauccc uccugaugaa gugaucccua uuggugcagc uauagaagca     1140

ggaauccuua uugggaaaga aaaccuguug guggaagacu cucuuaugau agaguguuca     1200

gccagagaua uuuuaguuaa ggguguggac gaaucaggag ccaguagauu cacagugcug     1260

uuuccaucag ggacuccuuu gccagcucga agacaacaca cauugcaagc cccuggaagc     1320

auaucuucag ugugccuuga acucuaugag ucugauggga agaacucugc caaagaggaa     1380

accaaguuug cacagguugu acuccaggau uuagauaaaa aagaaaaugg auuacgugau     1440

auauuagcug uucuuacuau gaaaagggau ggaucuuuac augugacaug cacagaucaa     1500

gaaacuggaa aaugugaagc aaucucuauu gagauagcau cuuagggacu aguuauaaga     1560

cugacuagcc cgaugggccu cccaacgggc ccuccucccc uccuugcacc gagauuaaua     1620

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1740

cagaauu                                                               1747


<210>  6039
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (wt)

<400>  6039
gggagaaagc uuaccauguc gguggugggg uuggacgugg gcucgcagag cugcuacauc       60

gcgguagccc gggccggggg caucgagacc aucgccaaug aguucagcga ccggugcacc      120

ccgucaguca uaucauuugg aucaaaaaau agaacaaucg gaguugcagc caaaaaucag      180

caaaucacuc augcaaacaa uacggugucu aacuucaaaa gauuucaugg ccgagcauuc      240

aaugaccccu ucauucaaaa ggagaaggaa aacuugaguu acgauuuggu uccauugaaa      300

aaugguggag uuggaauaaa gguaauguac augggugaag aacaucuauu uaguguggag      360

cagauaacag ccauguuguu gacuaagcug aaggaaacug cugaaaacag ccucaagaaa      420

ccaguaacag auuguguuau uucagucccc uccuucuuua cagaugcuga gaggcgaucu      480

guguuagaug cugcacagau uguuggccua aacuguuuaa gacuuaugaa ugacaugaca      540

gcuguugcuu ugaauuacgg aauuuauaag caggaucucc caagccugga ugagaaaccu      600

cggauagugg uuuuuguuga uaugggacau ucagcuuuuc aagugucugc uugugcuuuu      660

aacaagggaa aauugaaggu acugggaaca gcuuuugauc cuuucuuagg aggaaaaaac      720

uucgaugaaa aguuagugga acauuuuugu gcagaauuua aaacuaagua caaguuggau      780

gcaaaaucca aaauacgagc acuccuacgu cuguaucagg aaugugaaaa acugaaaaag      840

cuaaugagcu cuaacagcac agaccuucca cugaauaucg aaugcuuuau gaaugauaaa      900

gauguuuccg gaaagaugaa caggucacaa uuugaagaac ucugugcuga acuucugcaa      960

aagauagaag uaccccuuua uucacuguug gaacaaacuc aucucaaagu agaagaugug     1020

agugcaguug agauuguugg aggcgcuaca cgaaucccag cugugaagga aagaauugcc     1080

aaauucuuug gaaaagauau uagcacaaca cucaaugcag augaagcagu agccagagga     1140

ugugcauuac agugugcaau acuuuccccg gcauuuaaag uuagagaauu uuccgucaca     1200

gaugcaguuc cuuuuccaau aucucugauc uggaaccaug auucagaaga uacugaaggu     1260

guucaugaag ucuuuagucg aaaccaugcu gcuccuuucu ccaaaguucu caccuuucug     1320

agaagggggc cuuuugagcu agaagcauuc uauucugauc cccaaggagu uccauaucca     1380

gaagcaaaaa uaggccgcuu uguaguucag aauguuucug cacagaaaga uggagaaaaa     1440

ucuagaguaa aagucaaagu gcgagucaac acccauggca uuuucaccau cucuacggca     1500

ucuauggugg agaaaguccc aacugaggag aaugaaaugu cuucugaagc ugacauggag     1560

ugucugaauc agagaccacc agaaaaccca gacacugaua aaaaugucca gcaagacaac     1620

agugaagcug gaacacagcc ccagguacaa acugaugcuc aacaaaccuc acagucuccc     1680

ccuucaccug aacuuaccuc agaagaaaac aaaaucccag augcugacaa agcaaaugaa     1740

aaaaaaguug accagccucc agaagcuaaa aagcccaaaa uaaagguggu gaauguugag     1800

cugccuauug aagccaacuu ggucuggcag uuagggaaag accuucuuaa cauguauauu     1860

gagacagagg guaagaugau aaugcaagau aaauuggaaa aagaaaggaa ugaugcuaaa     1920

aaugcaguug aggaauaugu guaugaguuc agagacaagc uguguggacc auaugaaaaa     1980

uuuauaugug agcaggauca ucaaaauuuu uugagacucc ucacagaaac ugaagacugg     2040

cuguaugaag aaggagagga ccaagcuaaa caagcauaug uugacaaguu ggaagaauua     2100

augaaaauug gcacuccagu uaaaguucgg uuucaggaag cugaagaacg gccaaaaaug     2160

uuugaagaac uaggacagag gcugcagcau uaugccaaga uagcagcuga cuucagaaau     2220

aaggaugaga aauacaacca uauugaugag ucugaaauga aaaaagugga gaagucuguu     2280

aaugaaguga uggaauggau gaauaauguc augaaugcuc aggcuaaaaa gagucuugau     2340

caggauccag uuguacgugc ucaggaaauu aaaacaaaaa ucaaggaauu gaacaacaca     2400

ugugaacccg uuguaacaca accgaaacca aaaauugaau cacccaaacu ggaaagaacu     2460

ccaaauggcc caaauauuga uaaaaaggaa gaagauuuag aagacaaaaa caauuuuggu     2520

gcugaaccuc cacaucagaa uggugaaugu uacccuaaug agaaaaauuc uguuaauaug     2580

gacuuggacu agggacuagu uauaagacug acuagcccga ugggccuccc aacgggcccu     2640

ccuccccucc uugcaccgag auuaauaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  6040
<211>  3217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (wt)

<400>  6040
gggagaaagc uuaccauggc agacaaaguu aggaggcaga ggccgaggag gcgagucugu       60

ugggccuugg uggcugugcu cuuggcagac cuguuggcac ugagugauac acuggcagug      120

augucugugg accugggcag ugaguccaug aagguggcca uugucaaacc uggagugccc      180

auggaaauug ucuugaauaa ggaaucucgg aggaaaacac cggugaucgu gacccugaaa      240

gaaaaugaaa gauucuuugg agacagugca gcaagcaugg cgauuaagaa uccaaaggcu      300

acgcuacguu acuuccagca ccuccugggg aagcaggcag auaaccccca uguagcucuu      360

uaccaggccc gcuucccgga gcacgagcug acuuucgacc cacagaggca gacugugcac      420

uuucagauca gcucgcagcu gcaguucuca ccugaggaag uguugggcau gguucucaau      480

uauucucguu cucuagcuga agauuuugca gagcagccca ucaaggaugc agugaucacc      540

gugccagucu ucuucaacca ggccgagcgc cgagcugugc ugcaggcugc ucguauggcu      600

ggccucaaag ugcugcagcu caucaaugac aacaccgcca cugcccucag cuaugguguc      660

uuccgccgga aagauauuaa caccacugcc cagaauauca uguucuauga caugggcuca      720

ggcagcaccg uaugcaccau ugugaccuac cagaugguga agacuaagga agcugggaug      780

cagccacagc ugcagauccg gggaguagga uuugaccgua cccugggggg ccuggagaug      840

gagcuccggc uucgagaacg ccuggcuggg cuuuucaaug agcagcgcaa gggucagaga      900

gcaaaggaug ugcgggagaa cccgcgugcc auggccaagc ugcugcguga ggcuaaucgg      960

cucaaaaccg uccucagugc caacgcugac cacauggcac agauugaagg ccugauggau     1020

gauguggacu ucaaggcaaa agugacucgu guggaauuug aggaguugug ugcagacuug     1080

uuugagcggg ugccugggcc uguacagcag gcccuccaga gugccgaaau gagucuggau     1140

gagauugagc aggucauccu gguggguggg gccacucggg uccccagagu ucaggaggug     1200

cugcugaagg ccgugggcaa ggaggagcug gggaagaaca ucaaugcaga ugaagcagcc     1260

gccauggggg caguguacca ggcagcugcg cucagcaaag ccuuuaaagu gaagccauuu     1320

gucguccgag augcaguggu cuaccccauc cugguggagu ucacgaggga gguggaggag     1380

gagccuggga uucacagccu gaagcacaau aaacggguac ucuucucucg gauggggccc     1440

uacccucaac gcaaagucau caccuuuaac cgcuacagcc augauuucaa cuuccacauc     1500

aacuacggcg accugggcuu ccuggggccu gaagaucuuc ggguauuugg cucccagaau     1560

cugaccacag ugaagcuaaa aggggugggu gacagcuuca agaaguaucc ugacuacgag     1620

uccaagggca ucaaggcuca cuucaaccug gaugagagug gcgugcucag ucuagacagg     1680

guggagucug uauuugagac acugguagag gacagcgcag aagaggaauc uacucucacc     1740

aaacuuggca acaccauuuc cagccuguuu ggaggcggua ccacaccaga ugccaaggag     1800

aaugguacug auacugucca ggaggaagag gagagcccug cagaggggag caaggacgag     1860

ccuggggagc aggucgagcu caaggaggaa gcugaggccc caguggagga uggcucucag     1920

cccccacccc cugaaccuaa gggagaugca accccugagg gagaaaaggc cacagaaaaa     1980

gaaaaugggg acaagucuga ggcccagaaa ccaagugaga aggcagaggc agggccugag     2040

ggcgucgcuc cagccccaga gggagagaag aagcagaagc ccgccaggaa gcggcgaaug     2100

guagaggaga ucggggugga gcugguuguu cuggaccugc cugacuugcc agaggauaag     2160

cuggcucagu cggugcagaa acuucaggac uugacacucc gagaccugga gaagcaggaa     2220

cgggaaaaag cugccaacag cuuggaagca uucauauuug agacccagga caagcuguac     2280

cagcccgagu accaggaagu guccacagag gagcagcgug aggagaucuc ugggaagcuc     2340

agcgccgcau ccaccuggcu ggaggaugag gguguuggag ccaccacagu gauguugaag     2400

gagaagcugg cugagcugag gaagcugugc caagggcugu uuuuucgggu agaggagcgc     2460

aagaaguggc ccgaacggcu gucugcccuc gauaaucucc ucaaccauuc cagcauguuc     2520

cucaaggggg cccggcucau cccagagaug gaccagaucu ucacugaggu ggagaugaca     2580

acguuagaga aagucaucaa ugagaccugg gccuggaaga augcaacucu ggccgagcag     2640

gcuaagcugc ccgccacaga gaagccugug uugcucucaa aagacauuga agcuaagaug     2700

auggcccugg accgagaggu gcaguaucug cucaauaagg ccaaguuuac caagccccgg     2760

ccccggccua aggacaagaa ugggacccgg gcagagccac cccucaaugc cagugccagu     2820

gaccaggggg agaaggucau cccuccagca ggccagacug aagaugcaga gcccauuuca     2880

gaaccugaga aaguagagac uggauccgag ccaggagaca cugagccuuu ggaguuagga     2940

gguccuggag cagaaccuga acagaaagaa caaucgacag gacagaagcg gccuuugaag     3000

aacgacgaac uauaaggacu aguuauaaga cugacuagcc cgaugggccu cccaacgggc     3060

ccuccucccc uccuugcacc gagauuaaua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     3180

ccccccccca aaggcucuuu ucagagccac cagaauu                              3217


<210>  6041
<211>  2416
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (wt)

<400>  6041
gggagaaagc uuaccaugcc ugaggaaacc cagacccaag accaaccgau ggaggaggag       60

gagguugaga cguucgccuu ucaggcagaa auugcccagu ugaugucauu gaucaucaau      120

acuuucuacu cgaacaaaga gaucuuucug agagagcuca uuucaaauuc aucagaugca      180

uuggacaaaa uccgguauga gagcuugaca gaucccagua aauuagacuc ugggaaagag      240

cugcauauua accuuauacc gaacaaacaa gaucgaacuc ucacuauugu ggauacugga      300

auuggaauga ccaaggcuga cuugaucaau aaccuuggua cuaucgccaa gucugggacc      360

aaagcguuca uggaagcauu gcaggcuggu gcagauaucu cuaugauugg ccaguucggu      420

guugguuuuu auucugcuua uuugguugcu gagaaaguaa cugugaucac caaacauaac      480

gaugaugagc aguacgcuug ggaguccuca gcagggggau cauucacagu gaggacagac      540

acaggugaac cuaugggucg uggaacaaaa guuauccuac accugaaaga agaccaaacu      600

gaguacuugg aggaacgaag aauaaaggag auugugaaga aacauucuca guuuauugga      660

uaucccauua cucuuuuugu ggagaaggaa cgugauaaag aaguaagcga ugaugaggcu      720

gaagaaaagg aagacaaaga agaagaaaaa gaaaaagaag agaaagaguc ggaagacaaa      780

ccugaaauug aagauguugg uucugaugag gaagaagaaa agaaggaugg ugacaagaag      840

aagaagaaga agauuaagga aaaguacauc gaucaagaag aacucaacaa aacaaagccc      900

aucuggacca gaaaucccga cgauauuacu aaugaggagu acggagaguu cuauaagagc      960

uugaccaaug acugggaaga ucacuuggca gugaagcauu uuucaguuga aggacaguug     1020

gaguucagag cccuucuauu ugucccacga cgugcuccuu uugaucuguu ugaaaacaga     1080

aagaaaaaga acaacaucaa auuguaugua cgcagaguuu ucaucaugga uaacugugag     1140

gagcuaaucc cugaauaucu gaacuucauu agaggggugg uagacucgga ggaucucccu     1200

cuaaacauau cccgugagau guugcaacaa agcaaaauuu ugaaaguuau caggaagaau     1260

uuggucaaaa aaugcuuaga acucuuuacu gaacuggcgg aagauaaaga gaacuacaag     1320

aaauucuaug agcaguucuc uaaaaacaua aagcucggaa uacacgaaga cucucaaaau     1380

cggaagaagc ucucagagcu guuaagguac uacacaucug ccucugguga ugagaugguu     1440

ucucucaagg acuacugcac cagaaugaag gagaaccaga aacauaucua uuauaucaca     1500

ggugagacca aggaccaggu agcuaacuca gccuuugugg aacgucuucg gaaacauggc     1560

uuagaaguga ucuauaugau ugagcccauu gaugaguacu guguccaaca gcugaaggaa     1620

uuugagggga agacuuuagu gucagucacc aaagaaggcc uggaacuucc agaggaugaa     1680

gaagagaaaa agaagcagga agagaaaaaa acaaaguuug agaaccucug caaaaucaug     1740

aaagacauau uggagaaaaa aguugaaaag gugguugugu caaaccgauu ggugacaucu     1800

ccaugcugua uugucacaag cacauauggc uggacagcaa acauggagag aaucaugaaa     1860

gcucaagccc uaagagacaa cucaacaaug gguuacaugg cagcaaagaa acaccuggag     1920

auaaacccug accauuccau uauugagacc uuaaggcaaa aggcagaggc ugauaagaac     1980

gacaagucug ugaaggaucu ggucaucuug cuuuaugaaa cugcgcuccu gucuucuggc     2040

uucagucugg aagaucccca gacacaugcu aacaggaucu acaggaugau caaacuuggu     2100

cuggguauug augaagauga cccuacugcu gaugauacca gugcugcugu aacugaagaa     2160

augccacccc uugaaggaga ugacgacaca ucacgcaugg aagaaguaga cuaaggacua     2220

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     2280

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     2400

cagagccacc agaauu                                                     2416


<210>  6042
<211>  556
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (wt)

<400>  6042
gggagaaagc uuaccaugga uuccaguaaa uuagacucug ggaaagggcu gcauauuaac       60

cuuguaccaa acaaacaaaa ucaaacccuc acuauugugg acacuagaau uggaaugacc      120

aagacugacu ugaucaauaa ccucgguacu gucaccaagu cugggaccaa agcauucaug      180

gaagcauugc aggcugaugc agauaucucu augauuggcc auuucggggu ugguuuuuau      240

ucugcuuauu ugguugccaa gaaaguaacu gugaucagca aacauaacaa ugaugagcag      300

uacaccuggg aguccucagc agggggauca uucacaguga ggacagacga gugaggacua      360

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      420

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      540

cagagccacc agaauu                                                      556


<210>  6043
<211>  2392
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (wt)

<400>  6043
gggagaaagc uuaccaugcc ugaggaagug caccauggag aggaggaggu ggagacuuuu       60

gccuuucagg cagaaauugc ccaacucaug ucccucauca ucaauaccuu cuauuccaac      120

aaggagauuu uccuucggga guugaucucu aaugcuucug augccuugga caagauucgc      180

uaugagagcc ugacagaccc uucgaaguug gacaguggua aagagcugaa aauugacauc      240

auccccaacc cucaggaacg uacccugacu uugguagaca caggcauugg caugaccaaa      300

gcugaucuca uaaauaauuu gggaaccauu gccaagucug guacuaaagc auucauggag      360

gcucugcagg cuggugcaga caucuccaug auugggcagu uugguguugg cuuuuauucu      420

gccuacuugg uggcagagaa agugguugug aucacaaagc acaacgauga ugaacaguau      480

gcuugggagu cuucugcugg agguuccuuc acugugcgug cugaccaugg ugagcccauu      540

ggcaggggua ccaaagugau ccuccaucuu aaagaagauc agacagagua ccuagaagag      600

aggcggguca aagaaguagu gaagaagcau ucucaguuca uaggcuaucc caucacccuu      660

uauuuggaga aggaacgaga gaaggaaauu agugaugaug aggcagagga agagaaaggu      720

gagaaagaag aggaagauaa agaugaugaa gaaaaaccca agaucgaaga uguggguuca      780

gaugaggagg augacagcgg uaaggauaag aagaagaaaa cuaagaagau caaagagaaa      840

uacauugauc aggaagaacu aaacaagacc aagccuauuu ggaccagaaa cccugaugac      900

aucacccaag aggaguaugg agaguucuac aagagccuca cuaaugacug ggaagaccac      960

uuggcaguca agcacuuuuc uguagaaggu caguuggagu ucagggcauu gcuauuuauu     1020

ccucgucggg cucccuuuga ccuuuuugag aacaagaaga aaaagaacaa caucaaacuc     1080

uauguccgcc guguguucau cauggacagc ugugaugagu ugauaccaga guaucucaau     1140

uuuauccgug gugugguuga cucugaggau cugccccuga acaucucccg agaaaugcuc     1200

cagcagagca aaaucuugaa agucauucgc aaaaacauug uuaagaagug ccuugagcug     1260

uucucugagc uggcagaaga caaggagaau uacaagaaau ucuaugaggc auucucuaaa     1320

aaucucaagc ucggaaucca cgaagacucc acuaaccgcc gccgccuguc ugagcugcug     1380

cgcuaucaua ccucccaguc uggagaugag augacaucuc ugucagagua uguuucucgc     1440

augaaggaga cacagaaguc caucuauuac aucacuggug agagcaaaga gcaggucgcc     1500

aacucagcuu uuguggagcg agugcggaaa cggggcuucg aggugguaua uaugaccgag     1560

cccauugacg aguacugugu gcagcagcuc aaggaauuug augggaaaag ccuggucuca     1620

guuaccaagg agggucugga gcugccugag gaugaggagg agaagaagaa gauggaagag     1680

agcaaggcaa aguuugagaa ccucugcaag cucaugaaag aaaucuuaga uaagaagguu     1740

gagaagguga caaucuccaa uagacuugug ucuucaccuu gcugcauugu gaccagcacc     1800

uacggcugga cagccaauau ggagcggauc augaaagccc aggcacuucg ggacaacucc     1860

accaugggcu auaugauggc caaaaagcac cuggagauca acccugacca ccccauugug     1920

gagacgcugc ggcagaaggc ugaggccgac aagaaugaua aggcaguuaa ggaccuggug     1980

gugcugcugu uugaaaccgc ccugcuaucu ucuggcuuuu cccuugagga uccccagacc     2040

cacuccaacc gcaucuaucg caugaucaag cuaggucuag guauugauga agaugaagug     2100

gcagcagagg aacccaaugc ugcaguuccu gaugagaucc ccccucucga gggcgaugag     2160

gaugcgucuc gcauggaaga agucgauuag ggacuaguua uaagacugac uagcccgaug     2220

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2340

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2392


<210>  6044
<211>  2629
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (wt)

<400>  6044
gggagaaagc uuaccaugag ggcccugugg gugcugggcc ucugcugcgu ccugcugacc       60

uucgggucgg ucagagcuga cgaugaaguu gauguggaug guacaguaga agaggaucug      120

gguaaaagua gagaaggauc aaggacggau gaugaaguag uacagagaga ggaagaagcu      180

auucaguugg auggauuaaa ugcaucacaa auaagagaac uuagagagaa gucggaaaag      240

uuugccuucc aagccgaagu uaacagaaug augaaacuua ucaucaauuc auuguauaaa      300

aauaaagaga uuuuccugag agaacugauu ucaaaugcuu cugaugcuuu agauaagaua      360

aggcuaauau cacugacuga ugaaaaugcu cuuucuggaa augaggaacu aacagucaaa      420

auuaagugug auaaggagaa gaaccugcug caugucacag acaccggugu aggaaugacc      480

agagaagagu ugguuaaaaa ccuugguacc auagccaaau cugggacaag cgaguuuuua      540

aacaaaauga cugaagcaca ggaagauggc cagucaacuu cugaauugau uggccaguuu      600

ggugucgguu ucuauuccgc cuuccuugua gcagauaagg uuauugucac uucaaaacac      660

aacaacgaua cccagcacau cugggagucu gacuccaaug aauuuucugu aauugcugac      720

ccaagaggaa acacucuagg acggggaacg acaauuaccc uugucuuaaa agaagaagca      780

ucugauuacc uugaauugga uacaauuaaa aaucucguca aaaaauauuc acaguucaua      840

aacuuuccua uuuauguaug gagcagcaag acugaaacug uugaggagcc cauggaggaa      900

gaagaagcag ccaaagaaga gaaagaagaa ucugaugaug aagcugcagu agaggaagaa      960

gaagaagaaa agaaaccaaa gacuaaaaaa guugaaaaaa cugucuggga cugggaacuu     1020

augaaugaua ucaaaccaau auggcagaga ccaucaaaag aaguagaaga agaugaauac     1080

aaagcauucu acaaaucauu uucaaaggaa agugaugacc ccauggcuua uauucacuuu     1140

acugcugaag gggaaguuac cuucaaauca auuuuauuug uacccacauc ugcuccacgu     1200

ggucuguuug acgaauaugg aucuaaaaag agcgauuaca uuaagcucua ugugcgccgu     1260

guauucauca cagacgacuu ccaugauaug augccuaaau accucaauuu ugucaagggu     1320

gugguggacu cagaugaucu ccccuugaau guuucccgcg agacucuuca gcaacauaaa     1380

cugcuuaagg ugauuaggaa gaagcugguu cguaaaacgc uggacaugau caagaagauu     1440

gcugaugaua aauacaauga uacuuuuugg aaagaauuug guaccaacau caagcugggu     1500

gugauugaag accacucgaa ucgaacacgu cuugcuaaac uucuuagguu ccagucuucu     1560

caucauccaa cugacauuac uagccuagac caguaugugg aaagaaugaa ggaaaaacaa     1620

gacaaaaucu acuucauggc uggguccagc agaaaagagg cugaaucuuc uccauuuguu     1680

gagcgacuuc ugaaaaaggg cuaugaaguu auuuaccuca cagaaccugu ggaugaauac     1740

uguauucagg cccuucccga auuugauggg aagagguucc agaauguugc caaggaagga     1800

gugaaguucg augaaaguga gaaaacuaag gagagucgug aagcaguuga gaaagaauuu     1860

gagccucugc ugaauuggau gaaagauaaa gcccuuaagg acaagauuga aaaggcugug     1920

gugucucagc gccugacaga aucuccgugu gcuuuggugg ccagccagua cggauggucu     1980

ggcaacaugg agagaaucau gaaagcacaa gcguaccaaa cgggcaagga caucucuaca     2040

aauuacuaug cgagucagaa gaaaacauuu gaaauuaauc ccagacaccc gcugaucaga     2100

gacaugcuuc gacgaauuaa ggaagaugaa gaugauaaaa caguuuugga ucuugcugug     2160

guuuuguuug aaacagcaac gcuucgguca ggguaucuuu uaccagacac uaaagcauau     2220

ggagauagaa uagaaagaau gcuucgccuc aguuugaaca uugacccuga ugcaaaggug     2280

gaagaagaac ccgaagaaga accugaagag acagcagaag acacaacaga agacacagag     2340

caagacgaag augaagaaau ggauguggga acagaugaag aagaagaaac agcaaaggaa     2400

ucuacagcug aaaaagauga auuguaagga cuaguuauaa gacugacuag cccgaugggc     2460

cucccaacgg gcccuccucc ccuccuugca ccgagauuaa uaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2580

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2629


<210>  6045
<211>  2332
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (wt)

<400>  6045
gggagaaagc uuaccauggc gcgcgagcug cgggcgcugc ugcugugggg ccgccgccug       60

cggccuuugc ugcgggcgcc ggcgcuggcg gccgugccgg gaggaaaacc aauucugugu      120

ccucggagga ccacagccca guugggcccc aggcgaaacc cagccuggag cuugcaggca      180

ggacgacugu ucagcacgca gaccgccgag gacaaggagg aaccccugca cucgauuauc      240

agcagcacag agagcgugca ggguuccacu uccaaacaug aguuccaggc cgagacaaag      300

aagcuguugg acauuguugc ccggucccug uacucagaaa aagagguguu uauacgggag      360

cugaucucca augccagcga ugccuuggaa aaacugcguc acaaacuggu gucugacggc      420

caagcacugc cagaaaugga gauucacuug cagaccaaug ccgagaaagg caccaucacc      480

auccaggaua cugguaucgg gaugacacag gaagaacugg uguccaaccu ggggacgauu      540

gccagaucgg ggucaaaggc cuuccuggau gcucugcaga accaggcuga ggccagcagc      600

aagaucaucg gccaguuugg aguggguuuc uacucagcuu ucaugguggc ugacagagug      660

gaggucuauu cccgcucggc agccccgggg agccuggguu accaguggcu uucagauggu      720

ucuggagugu uugaaaucgc cgaagcaucg ggaguuagaa ccgggacaaa aaucaucauc      780

caccugaaau ccgacugcaa ggaguuuucc agcgaggccc gggugcgaga ugugguaacg      840

aaguacagca acuucgucag cuuccccuug uacuugaaug gaaggcggau gaacaccuug      900

caggccaucu ggaugaugga ccccaaggau guccgugagu ggcaacauga ggaguucuac      960

cgcuacgucg cgcaggcuca cgacaagccc cgcuacaccc ugcacuauaa gacggacgca     1020

ccgcucaaca uccgcagcau cuucuacgug cccgacauga aaccguccau guuugaugug     1080

agccgggagc ugggcuccag cguugcacug uacagccgca aaguccucau ccagaccaag     1140

gccacggaca uccugcccaa guggcugcgc uucauccgag guguggugga cagugaggac     1200

auuccccuga accucagccg ggagcugcug caggagagcg cacucaucag gaaacuccgg     1260

gacguuuuac agcagaggcu gaucaaauuc uucauugacc agaguaaaaa agaugcugag     1320

aaguaugcaa aguuuuuuga agauuacggc cuguucaugc gggagggcau ugugaccgcc     1380

accgagcagg aggucaagga ggacauagca aagcugcugc gcuacgaguc cucggcgcug     1440

cccuccgggc agcuaaccag ccucucagaa uacgccagcc gcaugcgggc cggcacccgc     1500

aacaucuacu accugugcgc ccccaaccgu caccuggcag agcacucacc cuacuaugag     1560

gccaugaaga agaaagacac agagguucuc uucugcuuug agcaguuuga ugagcucacc     1620

cugcugcacc uucgugaguu ugacaagaag aagcugaucu cuguggagac ggacauaguc     1680

guggaucacu acaaggagga gaaguuugag gacagguccc cagccgccga gugccuauca     1740

gagaaggaga cggaggagcu cauggccugg augagaaaug ugcugggguc gcgugucacc     1800

aacgugaagg ugacccuccg acuggacacc cacccugcca uggucaccgu gcuggagaug     1860

ggggcugccc gccacuuccu gcgcaugcag cagcuggcca agacccagga ggagcgcgca     1920

cagcuccugc agcccacgcu ggagaucaac cccaggcacg cgcucaucaa gaagcugaau     1980

cagcugcgcg caagcgagcc uggccuggcu cagcugcugg uggaucagau auacgagaac     2040

gccaugauug cugcuggacu uguugacgac ccuagggcca uggugggccg cuugaaugag     2100

cugcuuguca aggcccugga gcgacacuga ggacuaguua uaagacugac uagcccgaug     2160

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     2280

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             2332


<210>  6046
<211>  679
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (wt)

<400>  6046
gggagaaagc uuaccauggg aaaaaucagc agucuuccaa cccaauuauu uaagugcugc       60

uuuugugauu ucuugaaggu gaagaugcac accauguccu ccucgcaucu cuucuaccug      120

gcgcugugcc ugcucaccuu caccagcucu gccacggcug gaccggagac gcucugcggg      180

gcugagcugg uggaugcucu gcaguucgug uguggagaca ggggcuuuua uuucaacaag      240

cccacagggu auggcuccag cagucggagg gcgccucaga caggcaucgu ggaugagugc      300

ugcuuccgga gcugugaucu aaggaggcug gagauguauu gcgcaccccu caagccugcc      360

aagucagcuc gcucuguccg ugcccagcgc cacaccgaca ugcccaagac ccagaaggaa      420

guacauuuga agaacgcaag uagagggagu gcaggaaaca agaacuacag gauguaggga      480

cuaguuauaa gacugacuag cccgaugggc cucccaacgg gcccuccucc ccuccuugca      540

ccgagauuaa uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu      660

uuucagagcc accagaauu                                                   679


<210>  6047
<211>  856
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (wt)

<400>  6047
gggagaaagc uuaccaugaa cuccuucucc acaagcgccu ucgguccagu ugccuucucc       60

cuggggcugc uccugguguu gccugcugcc uucccugccc caguaccccc aggagaagau      120

uccaaagaug uagccgcccc acacagacag ccacucaccu cuucagaacg aauugacaaa      180

caaauucggu acauccucga cggcaucuca gcccugagaa aggagacaug uaacaagagu      240

aacaugugug aaagcagcaa agaggcacug gcagaaaaca accugaaccu uccaaagaug      300

gcugaaaaag auggaugcuu ccaaucugga uucaaugagg agacuugccu ggugaaaauc      360

aucacugguc uuuuggaguu ugagguauac cuagaguacc uccagaacag auuugagagu      420

agugaggaac aagccagagc ugugcagaug aguacaaaag uccugaucca guuccugcag      480

aaaaaggcaa agaaucuaga ugcaauaacc accccugacc caaccacaaa ugccagccug      540

cugacgaagc ugcaggcaca gaaccagugg cugcaggaca ugacaacuca ucucauucug      600

cgcagcuuua aggaguuccu gcaguccagc cugagggcuc ugcggcaaau guagggacua      660

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg      720

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      840

cagagccacc agaauu                                                      856


<210>  6048
<211>  1498
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (wt)

<400>  6048
gggagaaagc uuaccaugcc cuugcuuugg cugagaggau uucuguuggc aaguugcugg       60

auuauaguga ggaguucccc caccccagga uccgaggggc acagcgcggc ccccgacugu      120

ccguccugug cgcuggccgc ccucccaaag gauguaccca acucucagcc agagauggug      180

gaggccguca agaagcacau uuuaaacaug cugcacuuga agaagagacc cgaugucacc      240

cagccgguac ccaaggcggc gcuucugaac gcgaucagaa agcugcaugu gggcaaaguc      300

ggggagaacg gguaugugga gauagaggau gacauuggaa ggagggcaga aaugaaugaa      360

cuuauggagc agaccucgga gaucaucacg uuugccgagu caggaacagc caggaagacg      420

cugcacuucg agauuuccaa ggaaggcagu gaccugucag ugguggagcg ugcagaaguc      480

uggcuguucc uaaaaguccc caaggccaac aggaccagga ccaaagucac cauccgccuc      540

uuccagcagc agaagcaccc gcagggcagc uuggacacag gggaagaggc cgaggaagug      600

ggcuuaaagg gggagaggag ugaacuguug cucucugaaa aaguaguaga cgcucggaaa      660

agcaccuggc augucuuccc ugucuccagc agcauccagc gguugcugga ccagggcaag      720

agcucccugg acguucggau ugccugugag cagugccagg agaguggcgc cagcuugguu      780

cuccugggca agaagaagaa gaaagaagag gagggggaag ggaaaaagaa gggcggaggu      840

gaaggugggg caggagcaga ugaggaaaag gagcagucgc acagaccuuu ccucaugcug      900

caggcccggc agucugaaga ccacccucau cgccggcguc ggcggggcuu ggagugugau      960

ggcaagguca acaucugcug uaagaaacag uucuuuguca guuucaagga caucggcugg     1020

aaugacugga ucauugcucc cucuggcuau caugccaacu acugcgaggg ugagugcccg     1080

agccauauag caggcacguc cggguccuca cuguccuucc acucaacagu caucaaccac     1140

uaccgcaugc ggggccauag ccccuuugcc aaccucaaau cgugcugugu gcccaccaag     1200

cugagaccca uguccauguu guacuaugau gauggucaaa acaucaucaa aaaggacauu     1260

cagaacauga ucguggagga gugugggugc ucauagggac uaguuauaag acugacuagc     1320

ccgaugggcc ucccaacggg cccuccuccc cuccuugcac cgagauuaau aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1440

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1498


<210>  6049
<211>  3676
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (wt)

<400>  6049
gggagaaagc uuaccauggc ucucagaguc cuucuguuaa cagccuugac cuuaugucau       60

ggguucaacu uggacacuga aaacgcaaug accuuccaag agaacgcaag gggcuucggg      120

cagagcgugg uccagcuuca gggauccagg guggugguug gagcccccca ggagauagug      180

gcugccaacc aaaggggcag ccucuaccag ugcgacuaca gcacaggcuc augcgagccc      240

auccgccugc agguccccgu ggaggccgug aacauguccc ugggccuguc ccuggcagcc      300

accaccagcc ccccucagcu gcuggccugu ggucccaccg ugcaccagac uugcagugag      360

aacacguaug ugaaagggcu cugcuuccug uuuggaucca accuacggca gcagccccag      420

aaguucccag aggcccuccg aggguguccu caagaggaua gugacauugc cuucuugauu      480

gauggcucug guagcaucau cccacaugac uuucggcgga ugaaggaguu ugucucaacu      540

gugauggagc aauuaaaaaa guccaaaacc uuguucucuu ugaugcagua cucugaagag      600

uuccggauuc acuuuaccuu caaagaguuc cagaacaacc cuaacccaag aucacuggug      660

aagccaauaa cgcagcugcu ugggcggaca cacacggcca cgggcauccg caaaguggua      720

cgagagcugu uuaacaucac caacggagcc cgaaagaaug ccuuuaagau ccuaguuguc      780

aucacggaug gagaaaaguu uggcgauccc uugggauaug aggaugucau cccugaggca      840

gacagagagg gagucauucg cuacgucauu ggggugggag augccuuccg cagugagaaa      900

ucccgccaag agcuuaauac caucgcaucc aagccgccuc gugaucacgu guuccaggug      960

aauaacuuug aggcucugaa gaccauucag aaccagcuuc gggagaagau cuuugcgauc     1020

gaggguacuc agacaggaag uagcagcucc uuugagcaug agaugucuca ggaaggcuuc     1080

agcgcugcca ucaccucuaa uggccccuug cugagcacug uggggagcua ugacugggcu     1140

gguggagucu uucuauauac aucaaaggag aaaagcaccu ucaucaacau gaccagagug     1200

gauucagaca ugaaugaugc uuacuugggu uaugcugccg ccaucaucuu acggaaccgg     1260

gugcaaagcc ugguucuggg ggcaccucga uaucagcaca ucggccuggu agcgauguuc     1320

aggcagaaca cuggcaugug ggaguccaac gcuaauguca agggcaccca gaucggcgcc     1380

uacuucgggg ccucccucug cuccguggac guggacagca acggcagcac cgaccugguc     1440

cucaucgggg ccccccauua cuacgagcag acccgagggg gccagguguc cgugugcccc     1500

uugcccaggg ggagggcucg guggcagugu gaugcuguuc ucuacgggga gcagggccaa     1560

cccuggggcc gcuuuggggc agcccuaaca gugcuggggg acguaaaugg ggacaagcug     1620

acggacgugg ccauuggggc cccaggagag gaggacaacc ggggugcugu uuaccuguuu     1680

cacggaaccu caggaucugg caucagcccc ucccauagcc agcggauagc aggcuccaag     1740

cucucuccca ggcuccagua uuuuggucag ucacugagug ggggccagga ccucacaaug     1800

gauggacugg uagaccugac uguaggagcc caggggcacg ugcugcugcu caggucccag     1860

ccaguacuga gagucaaggc aaucauggag uucaauccca gggaaguggc aaggaaugua     1920

uuugagugua augaucaggu ggugaaaggc aaggaagccg gagaggucag agucugccuc     1980

cauguccaga aaagcacacg ggaucggcua agagaaggac agauccagag uguugugacu     2040

uaugaccugg cucuggacuc cggccgccca cauucccgcg ccgucuucaa ugagacaaag     2100

aacagcacac gcagacagac acaggucuug gggcugaccc agacuuguga gacccugaaa     2160

cuacaguugc cgaauugcau cgaggaccca gugagcccca uugugcugcg ccugaacuuc     2220

ucucuggugg gaacgccauu gucugcuuuc gggaaccucc ggccagugcu ggcggaggau     2280

gcucagagac ucuucacagc cuuguuuccc uuugagaaga auuguggcaa ugacaacauc     2340

ugccaggaug accucagcau caccuucagu uucaugagcc uggacugccu cguggugggu     2400

gggccccggg aguucaacgu gacagugacu gugagaaaug auggugagga cuccuacagg     2460

acacagguca ccuucuucuu cccgcuugac cuguccuacc ggaagguguc cacgcuccag     2520

aaccagcgcu cacagcgauc cuggcgccug gccugugagu cugccuccuc caccgaagug     2580

ucuggggccu ugaaaagcac cagcugcagc auaaaccacc ccaucuuccc ggaaaacuca     2640

gaggucaccu uuaauaucac guuugaugua gacucuaagg cuucccuugg aaacaaacug     2700

cuccucaagg ccaaugugac cagugagaac aacaugccca gaaccaacaa aaccgaguuc     2760

caacuggagc ugccggugaa auaugcuguc uacauggugg ucaccagcca uggggucucc     2820

acuaaauauc ucaacuucac ggccucagag aauaccaguc gggucaugca gcaucaauau     2880

caggucagca accuggggca gaggagccuc cccaucagcc ugguguucuu ggugcccguc     2940

cggcugaacc agacugucau augggaccgc ccccagguca ccuucuccga gaaccucucg     3000

aguacgugcc acaccaagga gcgcuugccc ucucacuccg acuuucuggc ugagcuucgg     3060

aaggcccccg uggugaacug cuccaucgcu gucugccaga gaauccagug ugacaucccg     3120

uucuuuggca uccaggaaga guucaaugcu acccucaaag gcaaccucuc guuugacugg     3180

uacaucaaga ccucgcauaa ccaccuccug aucgugagca cagcugagau cuuguuuaac     3240

gauuccgugu ucacccugcu gccgggacag ggggcguuug ugagguccca gacggagacc     3300

aaaguggagc cguucgaggu ccccaacccc cugccgcuca ucgugggcag cucugucggg     3360

ggacugcugc uccuggcccu caucaccgcc gcgcuguaca agcucggcuu cuucaagcgg     3420

caauacaagg acaugaugag ugaagggggu cccccggggg ccgaacccca guagggacua     3480

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     3540

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     3660

cagagccacc agaauu                                                     3676


<210>  6050
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (wt)

<400>  6050
gggagaaagc uuaccauguu cucccugaag acgcuuccau uucugcucuu acuccaugug       60

cagauuucca aggccuuucc uguaucuucu aaagagaaaa auacaaaaac uguucaggac      120

uaccuggaaa aguucuacca auuaccaagc aaccaguauc agucuacaag gaagaauggc      180

acuaauguga ucguugaaaa gcugaaagaa augcagcgau uuuuuggguu gaaugugacg      240

gggaagccaa augaggaaac ucuggacaug augaaaaagc cucgcugugg agugccugac      300

aguggugguu uuauguuaac cccaggaaac cccaaguggg aacgcacuaa cuugaccuac      360

aggauucgaa acuauacccc acagcuguca gaggcugagg uagaaagagc uaucaaggau      420

gccuuugaac ucuggagugu ugcaucaccu cucaucuuca ccaggaucuc acagggagag      480

gcagauauca acauugcuuu uuaccaaaga gaucacggug acaauucucc auuugaugga      540

cccaauggaa uccuugcuca ugccuuucag ccaggccaag guauuggagg agaugcucau      600

uuugaugccg aagaaacaug gaccaacacc uccgcaaauu acaacuuguu ucuuguugcu      660

gcucaugaau uuggccauuc uuuggggcuc gcucacuccu cugacccugg ugccuugaug      720

uaucccaacu augcuuucag ggaaaccagc aacuacucac ucccucaaga ugacaucgau      780

ggcauucagg ccaucuaugg acuuucaagc aacccuaucc aaccuacugg accaagcaca      840

cccaaacccu gugaccccag uuugacauuu gaugcuauca ccacacuccg uggagaaaua      900

cuuuucuuua aagacaggua cuucuggaga aggcauccuc agcuacaaag agucgaaaug      960

aauuuuauuu cucuauucug gccaucccuu ccaacuggua uacaggcugc uuaugaagau     1020

uuugacagag accucauuuu ccuauuuaaa ggcaaccaau acugggcucu gaguggcuau     1080

gauauucugc aagguuaucc caaggauaua ucaaacuaug gcuuccccag cagcguccaa     1140

gcaauugacg cagcuguuuu cuacagaagu aaaacauacu ucuuuguaaa ugaccaauuc     1200

uggagauaug auaaccaaag acaauucaug gagccagguu aucccaaaag cauaucaggu     1260

gccuuuccag gaauagagag uaaaguugau gcaguuuucc agcaagaaca uuucuuccau     1320

gucuucagug gaccaagaua uuacgcauuu gaucuuauug cucagagagu uaccagaguu     1380

gcaagaggca auaaauggcu uaacuguaga uauggcugag gacuaguuau aagacugacu     1440

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  6051
<211>  2341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (wt)

<400>  6051
gggagaaagc uuaccaugag ccucuggcag ccccuggucc uggugcuccu ggugcugggc       60

ugcugcuuug cugcccccag acagcgccag uccacccuug ugcuguuccc uggagaccug      120

agaaccaauc ucaccgacag gcagcuggca gaggaauacc uguaccgcua ugguuacacu      180

cggguggcag agaugcgugg agagucgaaa ucucuggggc cugcgcugcu gcuucuccag      240

aagcaacugu cccugcccga gaccggugag cuggauagcg ccacgcugaa ggccaugcga      300

accccacggu gcgggguccc agaccugggc agauuccaaa ccuuugaggg cgaccucaag      360

uggcaccacc acaacaucac cuauuggauc caaaacuacu cggaagacuu gccgcgggcg      420

gugauugacg acgccuuugc ccgcgccuuc gcacugugga gcgcggugac gccgcucacc      480

uucacucgcg uguacagccg ggacgcagac aucgucaucc aguuuggugu cgcggagcac      540

ggagacgggu aucccuucga cgggaaggac gggcuccugg cacacgccuu uccuccuggc      600

cccggcauuc agggagacgc ccauuucgac gaugacgagu uguggucccu gggcaagggc      660

gucgugguuc caacucgguu uggaaacgca gauggcgcgg ccugccacuu ccccuucauc      720

uucgagggcc gcuccuacuc ugccugcacc accgacgguc gcuccgacgg cuugcccugg      780

ugcaguacca cggccaacua cgacaccgac gaccgguuug gcuucugccc cagcgagaga      840

cucuacaccc aggacggcaa ugcugauggg aaacccugcc aguuuccauu caucuuccaa      900

ggccaauccu acuccgccug caccacggac ggucgcuccg acggcuaccg cuggugcgcc      960

accaccgcca acuacgaccg ggacaagcug uucggcuucu gcccgacccg agcugacucg     1020

acggugaugg ggggcaacuc ggcgggggag cugugcgucu uccccuucac uuuccugggu     1080

aaggaguacu cgaccuguac cagcgagggc cgcggagaug ggcgccucug gugcgcuacc     1140

accucgaacu uugacagcga caagaagugg ggcuucugcc cggaccaagg auacaguuug     1200

uuccucgugg cggcgcauga guucggccac gcgcugggcu uagaucauuc cucagugccg     1260

gaggcgcuca uguacccuau guaccgcuuc acugaggggc cccccuugca uaaggacgac     1320

gugaauggca uccggcaccu cuaugguccu cgcccugaac cugagccacg gccuccaacc     1380

accaccacac cgcagcccac ggcucccccg acggucugcc ccaccggacc ccccacuguc     1440

caccccucag agcgccccac agcuggcccc acaggucccc ccucagcugg ccccacaggu     1500

ccccccacug cuggcccuuc uacggccacu acugugccuu ugaguccggu ggacgaugcc     1560

ugcaacguga acaucuucga cgccaucgcg gagauuggga accagcugua uuuguucaag     1620

gaugggaagu acuggcgauu cucugagggc agggggagcc ggccgcaggg ccccuuccuu     1680

aucgccgaca aguggcccgc gcugccccgc aagcuggacu cggucuuuga ggagcggcuc     1740

uccaagaagc uguucuucuu cucugggcgc cagguguggg uguacacagg cgcgucggug     1800

cugggcccga ggcgucugga caagcugggc cugggagccg acguggccca ggugaccggg     1860

gcccuccgga guggcagggg gaagaugcug cuguucagcg ggcggcgccu cuggagguuc     1920

gacgugaagg cgcagauggu ggauccccgg agcgccagcg agguggaccg gauguucccc     1980

ggggugccuu uggacacgca cgacgucuuc caguaccgag agaaagccua uuucugccag     2040

gaccgcuucu acuggcgcgu gaguucccgg agugaguuga accaggugga ccaagugggc     2100

uacgugaccu augacauccu gcagugcccu gaggacuagg gacuaguuau aagacugacu     2160

agcccgaugg gccucccaac gggcccuccu ccccuccuug caccgagauu aauaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2280

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2340

u                                                                     2341


<210>  6052
<211>  1285
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (wt)

<400>  6052
gggagaaagc uuaccaugga aacuccaaac accacagagg acuaugacac gaccacagag       60

uuugacuaug gggaugcaac uccgugccag aaggugaacg agagggccuu uggggcccaa      120

cugcugcccc cucuguacuc cuugguauuu gucauuggcc ugguuggaaa cauccuggug      180

guccuggucc uugugcaaua caagaggcua aaaaacauga ccagcaucua ccuccugaac      240

cuggccauuu cugaccugcu guuccuguuc acgcuucccu ucuggaucga cuacaaguug      300

aaggaugacu ggguuuuugg ugaugccaug uguaagaucc ucucuggguu uuauuacaca      360

ggcuuguaca gcgagaucuu uuucaucauc cugcugacga uugacaggua ccuggccauc      420

guccacgccg uguuugccuu gcgggcacgg accgucacuu uuggugucau caccagcauc      480

aucauuuggg cccuggccau cuuggcuucc augccaggcu uauacuuuuc caagacccaa      540

ugggaguuca cucaccacac cuguagccuu cacuuuccuc acgaaagccu acgagagugg      600

aagcuguuuc aggcucugaa acugaaccuc uuugggcugg uauugccuuu guuggucaug      660

aucaucugcu acacagggau uauaaagauu cugcuaagac gaccaaauga gaagaaaucc      720

aaagcugucc guuugauuuu ugucaucaug aucaucuuuu uucucuuuug gacccccuac      780

aauuugacua uacuuauuuc uguuuuccaa gacuuccugu ucacccauga gugugagcag      840

agcagacauu uggaccuggc ugugcaagug acggagguga ucgccuacac gcacugcugu      900

gucaacccag ugaucuacgc cuucguuggu gagagguucc ggaaguaccu gcggcaguug      960

uuccacaggc guguggcugu gcaccugguu aaauggcucc ccuuccucuc cguggacagg     1020

cuggagaggg ucagcuccac aucucccucc acaggggagc augaacucuc ugcuggguuc     1080

ugaggacuag uuauaagacu gacuagcccg augggccucc caacgggccc uccuccccuc     1140

cuugcaccga gauuaauaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     1260

ggcucuuuuc agagccacca gaauu                                           1285


<210>  6053
<211>  943
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (wt)

<400>  6053
gggagaaagc uuaccaugaa ucgcugcugg gcgcuguucc ugucucucug cugcuaccug       60

cgucugguca gcgccgaggg ggaccccauu cccgaggagc uuuaugagau gcugagugac      120

cacucgaucc gcuccuuuga ugaucuccaa cgccugcugc acggagaccc cggagaggaa      180

gauggggccg aguuggaccu gaacaugacc cgcucccacu cuggaggcga gcuggagagc      240

uuggcucgug gaagaaggag ccuggguucc cugaccauug cugagccggc caugaucgcc      300

gagugcaaga cgcgcaccga gguguucgag aucucccggc gccucauaga ccgcaccaac      360

gccaacuucc ugguguggcc gcccugugug gaggugcagc gcugcuccgg cugcugcaac      420

aaccgcaacg ugcagugccg ccccacccag gugcagcugc gaccugucca ggugagaaag      480

aucgagauug ugcggaagaa gccaaucuuu aagaaggcca cggugacgcu ggaagaccac      540

cuggcaugca agugugagac aguggcagcu gcacggccug ugacccgaag cccggggggu      600

ucccaggagc agcgagccaa aacgccccaa acucggguga ccauucggac ggugcgaguc      660

cgccggcccc ccaagggcaa gcaccggaaa uucaagcaca cgcaugacaa gacggcacug      720

aaggagaccc uuggagccua gggacuaguu auaagacuga cuagcccgau gggccuccca      780

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc      900

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                        943


<210>  6054
<211>  1312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (wt)

<400>  6054
gggagaaagc uuaccaugca ccggcucauc uuugucuaca cucuaaucug cgcaaacuuu       60

ugcagcuguc gggacacuuc ugcaaccccg cagagcgcau ccaucaaagc auugcgcaac      120

gccaaccuca ggcgagauga cuuguaccga agagaugaga ccauccaggu gaaaggaaac      180

ggcuacgugc agaguccuag auucccgaac agcuacccca ggaaccugcu ccugacaugg      240

cggcuucacu cucaggagaa uacacggaua cagcuagugu uugacaauca guuuggauua      300

gaggaagcag aaaaugauau cuguagguau gauuuugugg aaguugaaga uauauccgaa      360

accaguacca uuauuagagg acgauggugu ggacacaagg aaguuccucc aaggauaaaa      420

ucaagaacga accaaauuaa aaucacauuc aaguccgaug acuacuuugu ggcuaaaccu      480

ggauucaaga uuuauuauuc uuugcuggaa gauuuccaac ccgcagcagc uucagagacc      540

aacugggaau cugucacaag cucuauuuca gggguauccu auaacucucc aucaguaacg      600

gaucccacuc ugauugcgga ugcucuggac aaaaaaauug cagaauuuga uacaguggaa      660

gaucugcuca aguacuucaa uccagaguca uggcaagaag aucuugagaa uauguaucug      720

gacaccccuc gguaucgagg caggucauac caugaccgga agucaaaagu ugaccuggau      780

aggcucaaug augaugccaa gcguuacagu ugcacuccca ggaauuacuc ggucaauaua      840

agagaagaac ugaaguuggc caaugugguc uucuuuccac guugccuccu cgugcagcgc      900

uguggaggaa auuguggcug uggaacuguc aacuggaggu ccugcacaug caauucaggg      960

aaaaccguga aaaaguauca ugagguauua caguuugagc cuggccacau caagaggagg     1020

gguagagcua agaccauggc ucuaguugac auccaguugg aucaccauga acgaugugau     1080

uguaucugca gcucaagacc accucgauaa ggacuaguua uaagacugac uagcccgaug     1140

ggccucccaa cgggcccucc uccccuccuu gcaccgagau uaauaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1260

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1312


<210>  6055
<211>  895
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (wt)

<400>  6055
gggagaaagc uuaccauggu cacccacagc aaguuucccg ccgccgggau gagccgcccc       60

cuggacacca gccugcgccu caagaccuuc agcuccaaga gcgaguacca gcugguggug      120

aacgcagugc gcaagcugca ggagagcggc uucuacugga gcgcagugac cggcggcgag      180

gcgaaccugc ugcucagugc cgagcccgcc ggcaccuuuc ugauccgcga cagcucggac      240

cagcgccacu ucuucacgcu cagcgucaag acccagucug ggaccaagaa ccugcgcauc      300

cagugugagg ggggcagcuu cucucugcag agcgaucccc ggagcacgca gcccgugccc      360

cgcuucgacu gcgugcucaa gcuggugcac cacuacaugc cgcccccugg agcccccucc      420

uuccccucgc caccuacuga acccuccucc gaggugcccg agcagccguc ugcccagcca      480

cucccuggga guccccccag aagggccuau uacaucuacu ccgggggcga gaagaucccc      540

cugguguuga gccggccccu cuccuccaac guggccacuc uucagcaucu cugucggaag      600

accgucaacg gccaccugga cuccuaugag aaagucaccc agcugccggg gcccauucgg      660

gaguuccugg accaguacga ugccccgcuu uaaggacuag uuauaagacu gacuagcccg      720

augggccucc caacgggccc uccuccccuc cuugcaccga gauuaauaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc      840

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu           895


<210>  6056
<211>  1390
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (wt)

<400>  6056
gggagaaagc uuaccaugcc gcccuccggg cugcggcugc ugccgcugcu gcuaccgcug       60

cuguggcuac uggugcugac gccuggccgg ccggccgcgg gacuauccac cuguaagacu      120

aucgacaugg agcuggugaa gcggaagcgc aucgaggcca uccgcggcca gauccugucc      180

aagcugcggc ucgccagccc cccgagccag ggggaggugc cgcccggccc gcugcccgag      240

gccgugcucg cccuguacaa cagcacccgc gaccgggugg ccggggagag ugcagaaccg      300

gagcccgagc cugaggccga cuacuacgcc aaggagguca cccgcgugcu aaugguggaa      360

acccacaacg aaaucuauga caaguucaag cagaguacac acagcauaua uauguucuuc      420

aacacaucag agcuccgaga agcgguaccu gaacccgugu ugcucucccg ggcagagcug      480

cgucugcuga ggcucaaguu aaaaguggag cagcacgugg agcuguacca gaaauacagc      540

aacaauuccu ggcgauaccu cagcaaccgg cugcuggcac ccagcgacuc gccagagugg      600

uuaucuuuug augucaccgg aguugugcgg cagugguuga gccguggagg ggaaauugag      660

ggcuuucgcc uuagcgccca cugcuccugu gacagcaggg auaacacacu gcaaguggac      720

aucaacgggu ucacuaccgg ccgccgaggu gaccuggcca ccauucaugg caugaaccgg      780

ccuuuccugc uucucauggc caccccgcug gagagggccc agcaucugca aagcucccgg      840

caccgccgag cccuggacac caacuauugc uucagcucca cggagaagaa cugcugcgug      900

cggcagcugu acauugacuu ccgcaaggac cucggcugga aguggaucca cgagcccaag      960

ggcuaccaug ccaacuucug ccucgggccc ugccccuaca uuuggagccu ggacacgcag     1020

uacagcaagg uccuggcccu guacaaccag cauaacccgg gcgccucggc ggcgccgugc     1080

ugcgugccgc aggcgcugga gccgcugccc aucguguacu acgugggccg caagcccaag     1140

guggagcagc uguccaacau gaucgugcgc uccugcaagu gcagcugagg acuaguuaua     1200

agacugacua gcccgauggg ccucccaacg ggcccuccuc cccuccuugc accgagauua     1260

auaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1320

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1380

caccagaauu                                                            1390


<210>  6057
<211>  1462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (wt)

<400>  6057
gggagaaagc uuaccaugca cuacugugug cugagcgcuu uucugauccu gcaucugguc       60

acggucgcgc ucagccuguc uaccugcagc acacucgaua uggaccaguu caugcgcaag      120

aggaucgagg cgauccgcgg gcagauccug agcaagcuga agcucaccag ucccccagaa      180

gacuauccug agcccgagga aguccccccg gaggugauuu ccaucuacaa cagcaccagg      240

gacuugcucc aggagaaggc gagccggagg gcggccgccu gcgagcgcga gaggagcgac      300

gaagaguacu acgccaagga gguuuacaaa auagacaugc cgcccuucuu ccccuccgaa      360

aaugccaucc cgcccacuuu cuacagaccc uacuucagaa uuguucgauu ugacgucuca      420

gcaauggaga agaaugcuuc caauuuggug aaagcagagu ucagagucuu ucguuugcag      480

aacccaaaag ccagagugcc ugaacaacgg auugagcuau aucagauucu caaguccaaa      540

gauuuaacau cuccaaccca gcgcuacauc gacagcaaag uugugaaaac aagagcagaa      600

ggcgaauggc ucuccuucga uguaacugau gcuguucaug aauggcuuca ccauaaagac      660

aggaaccugg gauuuaaaau uagcuuacac ugucccugcu gcacuuuugu accaucuaau      720

aauuacauca ucccaaauaa aagugaagaa cuagaagcaa gauuugcagg uauugauggc      780

accuccacau auaccagugg ugaucagaaa acuauaaagu ccacuaggaa aaaaaacagu      840

gggaagaccc cacaucuccu gcuaauguua uugcccuccu acagacuuga gucacaacag      900

accaaccggc ggaagaagcg ugcuuuggau gcggccuauu gcuuuagaaa ugugcaggau      960

aauugcugcc uacguccacu uuacauugau uucaagaggg aucuagggug gaaauggaua     1020

cacgaaccca aaggguacaa ugccaacuuc ugugcuggag caugcccgua uuuauggagu     1080

ucagacacuc agcacagcag gguccugagc uuauauaaua ccauaaaucc agaagcaucu     1140

gcuucuccuu gcugcguguc ccaagauuua gaaccucuaa ccauucucua cuacauuggc     1200

aaaacaccca agauugaaca gcuuucuaau augauuguaa agucuugcaa augcagcuaa     1260

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1320

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1440

ucuuuucaga gccaccagaa uu                                              1462


<210>  6058
<211>  1456
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (wt)

<400>  6058
gggagaaagc uuaccaugaa gaugcacuug caaagggcuc uggugguccu ggcccugcug       60

aacuuugcca cggucagccu cucucugucc acuugcacca ccuuggacuu cggccacauc      120

aagaagaaga ggguggaagc cauuagggga cagaucuuga gcaagcucag gcucaccagc      180

cccccugagc caacggugau gacccacguc cccuaucagg uccuggcccu uuacaacagc      240

acccgggagc ugcuggagga gaugcauggg gagagggagg aaggcugcac ccaggaaaac      300

accgagucgg aauacuaugc caaagaaauc cauaaauucg acaugaucca ggggcuggcg      360

gagcacaacg aacuggcugu cugcccuaaa ggaauuaccu ccaagguuuu ccgcuucaau      420

guguccucag uggagaaaaa uagaaccaac cuauuccgag cagaguuccg ggucuugcgg      480

gugcccaacc ccagcucuaa gcggaaugag cagaggaucg agcuguucca gauccuucgg      540

ccagaugagc acauugccaa acagcgcuau aucgguggca agaaucugcc cacacggggc      600

acugccgagu ggcuguccuu ugaugucacu gacacugugc gugaguggcu guugagaaga      660

gaguccaacu uaggucuaga aaucagcauu cacuguccau gucacaccuu ucagcccaau      720

ggagauaucc uggaaaacau ucacgaggug auggaaauca aauucaaagg cguggacaau      780

gaggaugacc auggccgugg agaucugggg cgccucaaga agcagaagga ucaccacaac      840

ccucaucuaa uccucaugau gauuccccca caccggcucg acaacccggg ccaggggggu      900

cagaggaaga agcgggcuuu ggacaccaau uacugcuucc gcaacuugga ggagaacugc      960

ugugugcgcc cccucuacau ugacuuccga caggaucugg gcuggaagug gguccaugaa     1020

ccuaagggcu acuaugccaa cuucugcuca ggcccuugcc cauaccuccg cagugcagac     1080

acaacccaca gcacggugcu gggacuguac aacacucuga acccugaagc aucugccucg     1140

ccuugcugcg ugccccagga ccuggagccc cugaccaucc uguacuaugu ugggaggacc     1200

cccaaagugg agcagcucuc caacauggug gugaagucuu guaaauguag cugaggacua     1260

guuauaagac ugacuagccc gaugggccuc ccaacgggcc cuccuccccu ccuugcaccg     1320

agauuaauaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu     1440

cagagccacc agaauu                                                     1456


<210>  6059
<211>  1603
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (wt)

<400>  6059
gggagaaagc uuaccauggc gcccgucgcc gucugggccg cgcuggccgu cggacuggag       60

cucugggcug cggcgcacgc cuugcccgcc cagguggcau uuacacccua cgccccggag      120

cccgggagca caugccggcu cagagaauac uaugaccaga cagcucagau gugcugcagc      180

aaaugcucgc cgggccaaca ugcaaaaguc uucuguacca agaccucgga caccgugugu      240

gacuccugug aggacagcac auacacccag cucuggaacu ggguucccga gugcuugagc      300

uguggcuccc gcuguagcuc ugaccaggug gaaacucaag ccugcacucg ggaacagaac      360

cgcaucugca ccuguaggcc cggcugguac ugcgcgcuga gcaagcagga ggggugccgg      420

cugugcgcgc cgcugcgcaa gugccgcccg ggcuucggcg uggccagacc aggaacugaa      480

acaucagacg uggugugcaa gcccugugcc ccggggacgu ucuccaacac gacuucaucc      540

acggauauuu gcaggcccca ccagaucugu aacguggugg ccaucccugg gaaugcaagc      600

auggaugcag ucugcacguc cacguccccc acccggagua uggccccagg ggcaguacac      660

uuaccccagc caguguccac acgaucccaa cacacgcagc caacuccaga acccagcacu      720

gcuccaagca ccuccuuccu gcucccaaug ggccccagcc ccccagcuga agggagcacu      780

ggcgacuucg cucugccagu uggacugauu guggguguga cagccuuggg ucuacuaaua      840

auaggagugg ugaacugugu caucaugacc caggugaaaa agaagcccuu gugccugcag      900

agagaagcca aggugccuca cuugccugcc gauaaggccc gggguacaca gggccccgag      960

cagcagcacc uccugaucac agcgccgagc uccagcagca gcucccugga gagcucggcc     1020

agugcguugg acagaagggc gcccacucgg aaccagccac aggcaccagg cguggaggcc     1080

aguggggccg gggaggcccg ggccagcacc gggagcucag auucuucccc ugguggccau     1140

gggacccagg ucaaugucac cuguaucgug aacgucugua gcagcucuga ccacagcuca     1200

cagugcuccu cccaagccag cuccacaaug ggagacacag auuccagccc cucggagucc     1260

ccgaaggacg agcagguccc cuucuccaag gaggaaugug ccuuucgguc acagcuggag     1320

acgccagaga cccugcuggg gagcaccgaa gagaagcccc ugccccuugg agugccugau     1380

gcugggauga agcccaguua aggacuaguu auaagacuga cuagcccgau gggccuccca     1440

acgggcccuc cuccccuccu ugcaccgaga uuaauaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1560

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1603


<210>  6060
<211>  1282
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design1 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (wt)

<400>  6060
gggagaaagc uuaccaugua cagagagugg guagugguga auguuuucau gauguuguac       60

guccagcugg ugcagggcuc caguaaugaa cauggaccag ugaagcgauc aucucagucc      120

acauuggaac gaucugaaca gcagaucagg gcugcuucua guuuggagga acuacuucga      180

auuacucacu cugaggacug gaagcugugg agaugcaggc ugaggcucaa aaguuuuacc      240

aguauggacu cucgcucagc aucccaucgg uccacuaggu uugcggcaac uuucuaugac      300

auugaaacac uaaaaguuau agaugaagaa uggcaaagaa cucagugcag cccuagagaa      360

acgugcgugg agguggccag ugagcugggg aagaguacca acacauucuu caagcccccu      420

ugugugaacg uguuccgaug ugguggcugu ugcaaugaag agagccuuau cuguaugaac      480

accagcaccu cguacauuuc caaacagcuc uuugagauau cagugccuuu gacaucagua      540

ccugaauuag ugccuguuaa aguugccaau cauacagguu guaagugcuu gccaacagcc      600

ccccgccauc cauacucaau uaucagaaga uccauccaga ucccugaaga agaucgcugu      660

ucccauucca agaaacucug uccuauugac augcuauggg auagcaacaa auguaaaugu      720

guuuugcagg aggaaaaucc acuugcugga acagaagacc acucucaucu ccaggaacca      780

gcucucugug ggccacacau gauguuugac gaagaucguu gcgagugugu cuguaaaaca      840

ccauguccca aagaucuaau ccagcacccc aaaaacugca guugcuuuga gugcaaagaa      900

agucuggaga ccugcugcca gaagcacaag cuauuucacc cagacaccug uagcugugag      960

gacagaugcc ccuuucauac cagaccaugu gcaaguggca aaacagcaug ugcaaagcau     1020

ugccgcuuuc caaaggagaa aagggcugcc caggggcccc acagccgaaa gaauccuuga     1080

ggacuaguua uaagacugac uagcccgaug ggccucccaa cgggcccucc uccccuccuu     1140

gcaccgagau uaauaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1260

ucuuuucaga gccaccagaa uu                                              1282


<210>  6061
<211>  916
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (wt)

<400>  6061
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu guuugcuugc cuccugggag cagccuucuc uaugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu auauaagaca uccguacacu uccuaugggu      180

acgaacccau ggguggaugg cugcaccacc aaaucauacc cguggugucg cagcagacuc      240

cccagaguca ugcccuucag ccucaucacc acauccccau ggugccagcu caacagcccg      300

ggauccccca gcagccaaug augccacuuc cuggccaaca cuccaugacu ccaacccaac      360

accaccagcc aaaccucccu cugcccgccc agcagcccuu ccagccccag cccguccagc      420

cccagccuca ccagccccug cagccccagu cacccaugca ccccauccag cccuugcugc      480

cacagccacc ucugccuccg auguucucca ugcagucucu gcuuccugac cugccucugg      540

aagcauggcc agcaacagac aagaccaagc gggaggaagu ggauuaagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu      900

cagagccacc agaauu                                                      916


<210>  6062
<211>  952
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (wt)

<400>  6062
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu cuuugccugc cuuuugggag caucccuugc uaugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggugcu uaccccucug aagugguacc      180

agaacaugau aagacauccg uacacuuccu auggguacga acccaugggu ggauggcugc      240

accaccaaau cauacccgug gugucgcagc agacucccca gagucaugcc cuucagccuc      300

aucaccacau ccccauggug ccagcucaac agcccgggau cccccagcag ccaaugaugc      360

cacuuccugg ccaacacucc augacuccaa cccaacacca ccagccaaac cucccucugc      420

ccgcccagca gcccuuccag ccccagcccg uccagcccca gccucaccag ccccugcagc      480

cccagucacc caugcacccc auccagcccu ugcugccaca gccaccucug ccuccgaugu      540

ucuccaugca gucucugcuu ccugaccugc cucuggaagc auggccagca acagacaaga      600

ccaagcggga ggaaguggau uaaggacuag ugcaucacau uuaaaagcau cucagccuac      660

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      720

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      780

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      900

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              952


<210>  6063
<211>  601
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (wt)

<400>  6063
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu guuugcuugc cuccugggag cagccuucuc uaugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggugcu uaccccucug aagugguacc      180

agaacaugau aagacauccg ucucugcuuc cugaccugcc ucuggaagca uggccagcaa      240

cagacaagac caagcgggag gaaguggauu aaggacuagu gcaucacauu uaaaagcauc      300

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      360

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      420

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      540

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      600

u                                                                      601


<210>  6064
<211>  994
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (wt)

<400>  6064
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu guuugcuugc cuccugggag cagccuucuc uaugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggacuu auacuuggag gcuauccgua      180

uugacaggac ugcauucgug cuuaccccuc ugaaguggua ccagaacaug auaagacauc      240

cguacacuuc cuaugguuac gaacccaugg guggauggcu gcaccaccaa aucauucccg      300

uggugucgca gcagacuccc cagagucaug cccuucagcc ucaucaccac auccccaugg      360

ugccagcuca acagcccggg aucccccagc agccaaugau gccacuuccu ggccaacacu      420

ccaugacucc aacccaacac caccagccaa accucccucu gcccgcccag cagcccuucc      480

agccccagcc cguccagccc cagccucacc agccccugca gccccaguca cccaugcacc      540

ccauccagcc cuugcugcca cagccaccuc ugccuccgau guucuccaug cagucucugc      600

uuccugaccu gccucuggaa gcauggccag caacagacaa gaccaagcgg gaggaagugg      660

auuaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag      720

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac      780

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua      840

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc      960

ccccccaaag gcucuuuuca gagccaccag aauu                                  994


<210>  6065
<211>  880
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (wt)

<400>  6065
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggga       60

ccuggauuuu guuugcuugc cuccugggag cagccuucuc uaugccucua ccaccucauc      120

cugggcaccc ugguuauauc aacuucagcu augaggugcu uaccccucug aagugguacc      180

agaacaugau aagacauccg acuccccaga gucaugcccu ucagccucau caccacaucc      240

ccauggugcc agcucaacag cccgggaucc cccagcagcc aaugaugcca cuuccuggcc      300

aacacuccau gacuccaacc caacaccacc agccaaaccu cccucugccc gcccagcagc      360

ccuuccagcc ccagcccguc cagccccagc cucaccagcc ccugcagccc cagucaccca      420

ugcaccccau ccagcccuug cugccacagc caccucugcc uccgauguuc uccaugcagu      480

cucugcuucc ugaccugccu cuggaagcau ggccagcaac agacaagacc aagcgggagg      540

aaguggauua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      600

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      660

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      720

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc      840

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                            880


<210>  6066
<211>  904
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (wt)

<400>  6066
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccuc       60

uaccaccuca uccugggcac ccugguuaua ucaacuucag cuaugaggug cuuaccccuc      120

ugaaguggua ccagaacaug auaagacauc cguacacuuc cuauggguac gaacccaugg      180

guggauggcu gcaccaccaa aucauacccg uggugucgca gcagacuccc cagagucaug      240

cccuucagcc ucaucaccac auccccaugg ugccagcuca acagcccggg aucccccagc      300

agccaaugau gccacuuccu ggccaacacu ccaugacucc aacccaacac caccagccaa      360

accucccucu gcccgcccag cagcccuucc agccccagcc cguccagccc cagccucacc      420

agccccugca gccccaguca cccaugcacc ccauccagcc cuugcugcca cagccaccuc      480

ugccuccgau guucuccaug cagucucugc uuccugaccu gccucuggaa gcauggccag      540

caacagacaa gaccaagcgg gaggaagugg auuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      900

aauu                                                                   904


<210>  6067
<211>  3343
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (wt)

<400>  6067
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccg       60

gcguggcccg ccugccgcug cugcucgggc ugcugcugcu cccgcguccc ggccggccgc      120

uggacuuggc cgacuacacc uaugaccugg cggaggagga cgacucggag ccccucaacu      180

acaaagaccc cugcaaggcg gcugccuuuc uuggggacau ugcccuggac gaagaggacc      240

ugagggccuu ccagguacag caggcugugg aucucagacg gcacacagcu cguaaguccu      300

ccaucaaagc ugcaguucca ggaaacacuu cuacccccag cugccagagc accaacgggc      360

agccucagag gggagccugu gggagaugga gagguagauc ccguagccgg cgggcggcga      420

cgucccgacc agagcgugug uggcccgaug gggucauccc cuuugucauu gggggaaacu      480

ucacugguag ccagagggca gucuuccggc aggccaugag gcacugggag aagcacaccu      540

gugucaccuu ccuggagcgc acugacgagg acagcuauau uguguucacc uaucgaccuu      600

gcgggugcug cuccuacgug ggucgccgcg gcgggggccc ccaggccauc uccaucggca      660

agaacuguga caaguucggc auuguggucc acgagcuggg ccacgucguc ggcuucuggc      720

acgaacacac ucggccagac cgggaccgcc acguuuccau cguucgugag aacauccagc      780

cagggcagga guauaacuuc cugaagaugg agccucagga gguggagucc cugggggaga      840

ccuaugacuu cgacagcauc augcauuacg cucggaacac auucuccagg ggcaucuucc      900

uggauaccau uguccccaag uaugagguga acggggugaa accucccauu ggccaaagga      960

cacggcucag caagggggac auugcccaag cccgcaagcu guacaagugc ccagccugug     1020

gagagacccu gcaagacagc acaggcaacu ucuccucccc ugaauacccc aauggcuacu     1080

cugcucacau gcacugcgug uggcgcaucu cugucacacc cggggagaag aucauccuga     1140

acuucacguc ccuggaccug uaccgcagcc gccugugcug guacgacuau guggaggucc     1200

gagauggcuu cuggaggaag gcgccccucc gaggccgcuu cugcgggucc aaacucccug     1260

agccuaucgu cuccacugac agccgccucu ggguugaguu ccgcagcagc agcaauuggg     1320

uuggaaaggg cuucuuugca gucuacgaag ccaucugcgg gggugaugug aaaaaggacu     1380

auggccacau ucaaucgccc aacuacccag acgauuaccg gcccagcaaa gucugcaucu     1440

ggcggaucca ggugucugag ggcuuccacg ugggccucac auuccagucc uuugagauug     1500

agcgccacga cagcugugcc uacgacuauc uggaggugcg cgacgggcac agugagagca     1560

gcacccucau cgggcgcuac uguggcuaug agaagccuga ugacaucaag agcacgucca     1620

gccgccucug gcucaaguuc gucucugacg gguccauuaa caaagcgggc uuugccguca     1680

acuuuuucaa agagguggac gagugcucuc ggcccaaccg cgggggcugu gagcagcggu     1740

gccucaacac ccugggcagc uacaagugca gcugugaccc cggguacgag cuggccccag     1800

acaagcgccg cugugaggcu gcuuguggcg gauuccucac caagcucaac ggcuccauca     1860

ccagcccggg cuggcccaag gaguaccccc ccaacaagaa cugcaucugg cagcuggugg     1920

cccccaccca guaccgcauc ucccugcagu uugacuucuu ugagacagag ggcaaugaug     1980

ugugcaagua cgacuucgug gaggugcgca guggacucac agcugacucc aagcugcaug     2040

gcaaguucug ugguucugag aagcccgagg ucaucaccuc ccaguacaac aacaugcgcg     2100

uggaguucaa guccgacaac accgugucca aaaagggcuu caaggcccac uucuucucag     2160

acaaggacga gugcuccaag gauaacggcg gcugccagca ggacugcguc aacacguucg     2220

gcaguuauga gugccaaugc cgcaguggcu ucguccucca ugacaacaag cacgacugca     2280

aagaagccgg cugugaccac aaggugacau ccaccagugg uaccaucacc agccccaacu     2340

ggccugacaa guaucccagc aagaaggagu gcacgugggc caucuccagc acccccgggc     2400

accgggucaa gcugaccuuc auggagaugg acaucgaguc ccagccugag ugugccuacg     2460

accaccuaga gguguucgac gggcgagacg ccaaggcccc cguccucggc cgcuucugug     2520

ggagcaagaa gcccgagccc guccuggcca caggcagccg cauguuccug cgcuucuacu     2580

cagauaacuc gguccagcga aagggcuucc aggccuccca cgccacagag ugcgggggcc     2640

agguacgggc agacgugaag accaaggacc uuuacuccca cgcccaguuu ggcgacaaca     2700

acuacccugg ggguguggac ugugaguggg ucauuguggc cgaggaaggc uacggcgugg     2760

agcucguguu ccagaccuuu gagguggagg aggagaccga cugcggcuau gacuacaugg     2820

agcuguucga cggcuacgac agcacagccc ccaggcuggg gcgcuacugu ggcucagggc     2880

cuccugagga gguguacucg gcgggagauu cuguccuggu gaaguuccac ucggaugaca     2940

ccaucaccaa aaaagguuuc caccuccgau acaccagcac caaguuccag gacacacucc     3000

acagcaggaa gugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     3060

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     3120

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     3180

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     3300

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       3343


<210>  6068
<211>  1573
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (wt)

<400>  6068
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

ccgggacccg cugucuucua gcguugcugc uuccccaggu ccuccugggc ggcgcggcug      120

gccucguucc ggagcugggc cgcaggaagu ucgcggcggc gucgucgggc cgccccucau      180

cccagcccuc ugacgagguc cugagcgagu ucgaguugcg gcugcucagc auguucggcc      240

ugaaacagag acccaccccc agcagggacg ccguggugcc ccccuacaug cuagaccugu      300

aucgcaggca cucaggucag ccgggcucac ccgccccaga ccaccgguug gagagggcag      360

ccagccgagc caacacugug cgcagcuucc accaugaaga aucuuuggaa gaacuaccag      420

aaacgagugg gaaaacaacc cggagauucu ucuuuaauuu aaguucuauc cccacggagg      480

aguuuaucac cucagcagag cuucagguuu uccgagaaca gaugcaagau gcuuuaggaa      540

acaauagcag uuuccaucac cgaauuaaua uuuaugaaau cauaaaaccu gcaacagcca      600

acucgaaauu ccccgugacc agacuuuugg acaccagguu ggugaaucag aaugcaagca      660

gaugggaaag uuuugauguc acccccgcug ugaugcggug gacugcacag ggacacgcca      720

accauggauu cgugguggaa guggcccacu uggaggagaa acaagguguc uccaagagac      780

auguuaggau aagcaggucu uugcaccaag augaacacag cuggucacag auaaggccau      840

ugcuaguaac uuuuggccau gauggaaaag ggcauccucu ccacaaaaga gaaaaacguc      900

aagccaaaca caaacagcgg aaacgccuua aguccagcug uaagagacac ccuuuguacg      960

uggacuucag ugacgugggg uggaaugacu ggauuguggc ucccccgggg uaucacgccu     1020

uuuacugcca cggagaaugc ccuuuuccuc uggcugauca ucugaacucc acuaaucaug     1080

ccauuguuca gacguugguc aacucuguua acucuaagau uccuaaggca ugcugugucc     1140

cgacagaacu cagugcuauc ucgaugcugu accuugacga gaaugaaaag guuguauuaa     1200

agaacuauca ggacaugguu guggaggguu gugggugucg cuagggacua gugcaucaca     1260

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1320

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1380

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1440

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaau gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag     1560

agccaccaga auu                                                        1573


<210>  6069
<211>  1609
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (wt)

<400>  6069
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauuc       60

cugguaaccg aaugcugaug gucguuuuau uaugccaagu ccugcuagga ggcgcgagcc      120

augcuaguuu gauaccugag acggggaaga aaaaagucgc cgagauucag ggccacgcgg      180

gaggacgccg cucagggcag agccaugagc uccugcggga cuucgaggcg acacuucugc      240

agauguuugg gcugcgccgc cgcccgcagc cuagcaagag ugccgucauu ccggacuaca      300

ugcgggaucu uuaccggcuu cagucugggg aggaggagga agaacagauc cacagcacug      360

gucuugagua uccugagcgc ccggccagcc gggccaacac cgugaggagc uuccaccacg      420

aagaacaucu ggagaacauc ccagggacca gugaaaacuc ugcuuuucgu uuccucuuua      480

accucagcag caucccugag aacgagguga ucuccucugc agagcuucgg cuguuccggg      540

agcaggucga ccagggcccu gauugggaaa ggggcuucca ccguauaaac auuuaugagg      600

uuaugaagcc cccagcagaa guggugccug ggcaccucau cacacgacua cuggacacga      660

gacuggucca ccacaaugug acacgguggg aaacuuuuga ugugagcccu gcgguccuuc      720

gcuggacccg ggagaagcag ccaaacuaug ggcuagccau ugaggugacu caccuccauc      780

agacucggac ccaccagggc cagcauguca ggauuagccg aucguuaccu caagggagug      840

ggaauugggc ccagcuccgg ccccuccugg ucaccuuugg ccaugauggc cggggccaug      900

ccuugacccg acgccggagg gccaagcgua gcccuaagca ucacucacag cgggccagga      960

agaagaauaa gaacugccgg cgccacucgc ucuaugugga cuucagcgau gugggcugga     1020

augacuggau uguggcccca ccaggcuacc aggccuucua cugccauggg gacugccccu     1080

uuccacuggc ugaccaccuc aacucaacca accaugccau ugugcagacc cuggucaauu     1140

cugucaauuc caguaucccc aaagccuguu gugugcccac ugaacugagu gccaucucca     1200

ugcuguaccu ggaugaguau gauaaggugg uacugaaaaa uuaucaggag augguaguag     1260

agggaugugg gugccgcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     1320

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1380

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1440

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1560

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1609


<210>  6070
<211>  1924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (wt)

<400>  6070
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgg       60

ggcuggggcg gagggcgcag uggcugugcu gguggugggg gcugcugugc agcugcugcg      120

ggcccccgcc gcugcggccg cccuugcccg cugccgcggc cgccgccgcc ggggggcagc      180

ugcuggggga cggcgggagc cccggccgca cggagcagcc gccgccgucg ccgcaguccu      240

ccucgggcuu ccuguaccgg cggcucaaga cgcaggagaa gcgggagaug cagaaggaga      300

ucuugucggu gcuggggcuc ccgcaccggc cccggccccu gcacggccuc caacagccgc      360

agcccccggc gcuccggcag caggaggagc agcagcagca gcagcagcug ccucgcggag      420

agcccccucc cgggcgacug aaguccgcgc cccucuucau gcuggaucug uacaacgccc      480

uguccgccga caacgacgag gacggggcgu cggaggggga gaggcagcag uccuggcccc      540

acgaagcagc cagcucgucc cagcgucggc agccgccccc gggcgccgcg cacccgcuca      600

accgcaagag ccuucuggcc cccggaucug gcagcggcgg cgcgucccca cugaccagcg      660

cgcaggacag cgccuuccuc aacgacgcgg acauggucau gagcuuugug aaccuggugg      720

aguacgacaa ggaguucucc ccucgucagc gacaccacaa agaguucaag uucaacuuau      780

cccagauucc ugagggugag guggugacgg cugcagaguu ccgcaucuac aaggacugug      840

uuauggggag uuuuaaaaac caaacuuuuc uuaucagcau uuaucaaguc uuacaggagc      900

aucagcacag agacucugac cuguuuuugu uggacacccg uguaguaugg gccucagaag      960

aaggcuggcu ggaauuugac aucacggcca cuagcaaucu guggguugug acuccacagc     1020

auaacauggg gcuucagcug agcgugguga caagggaugg aguccacguc cacccccgag     1080

ccgcaggccu ggugggcaga gacggcccuu acgacaagca gcccuucaug guggcuuucu     1140

ucaaagugag ugaggugcac gugcgcacca ccaggucagc cuccagccgg cgccgacaac     1200

agagucguaa ucgcucuacc cagucccagg acguggcgcg ggucuccagu gcuucagauu     1260

acaacagcag ugaauugaaa acagccugca ggaagcauga gcuguaugug aguuuccaag     1320

accugggaug gcaggacugg aucauugcac ccaagggcua ugcugccaau uacugugaug     1380

gagaaugcuc cuucccacuc aacgcacaca ugaaugcaac caaccacgcg auugugcaga     1440

ccuugguuca ccuuaugaac cccgaguaug uccccaaacc gugcugugcg ccaacuaagc     1500

uaaaugccau cucgguucuu uacuuugaug acaacuccaa ugucauucug aaaaaauaca     1560

ggaauauggu uguaagagcu uguggaugcc acuaaggacu agugcaucac auuuaaaagc     1620

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu     1680

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc     1740

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag     1920

aauu                                                                  1924


<210>  6071
<211>  1678
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (wt)

<400>  6071
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacg       60

ugcgcucacu gcgagcugcg gcgccgcaca gcuucguggc gcucugggca ccccuguucc      120

ugcugcgcuc cgcccuggcc gacuucagcc uggacaacga ggugcacucg agcuucaucc      180

accggcgccu ccgcagccag gagcggcggg agaugcagcg cgagauccuc uccauuuugg      240

gcuugcccca ccgcccgcgc ccgcaccucc agggcaagca caacucggca cccauguuca      300

ugcuggaccu guacaacgcc auggcggugg aggagggcgg cgggcccggc ggccagggcu      360

ucuccuaccc cuacaaggcc gucuucagua cccagggccc cccucuggcc agccugcaag      420

auagccauuu ccucaccgac gccgacaugg ucaugagcuu cgucaaccuc guggaacaug      480

acaaggaguu cuuccaccca cgcuaccacc aucgagaguu ccgguuugau cuuuccaaga      540

ucccagaagg ggaagcuguc acggcagccg aguuccggau cuacaaggac uacauccggg      600

aacgcuucga caaugagacg uuccggauca gcguuuauca ggugcuccag gagcacuugg      660

gcagggaauc ggaucucuuc cugcucgaca gccguacccu cugggccucg gaggagggcu      720

ggcugguguu ugacaucaca gccaccagca accacugggu ggucaauccg cggcacaacc      780

ugggccugca gcucucggug gagacgcugg augggcagag caucaacccc aaguuggcgg      840

gccugauugg gcggcacggg ccccagaaca agcagcccuu caugguggcu uucuucaagg      900

ccacggaggu ccacuuccgc agcauccggu ccacggggag caaacagcgc agccagaacc      960

gcuccaagac gcccaagaac caggaagccc ugcggauggc caacguggca gagaacagca     1020

gcagcgacca gaggcaggcc uguaagaagc acgagcugua ugucagcuuc cgagaccugg     1080

gcuggcagga cuggaucauc gcgccugaag gcuacgccgc cuacuacugu gagggggagu     1140

gugccuuccc ucugaacucc uacaugaacg ccaccaacca cgccaucgug cagacgcugg     1200

uccacuucau caacccggaa acggugccca agcccugcug ugcgcccacg cagcucaaug     1260

ccaucuccgu ccucuacuuc gaugacagcu ccaacgucau ccugaagaaa uacagaaaca     1320

uggugguccg ggccuguggc ugccacuagg gacuagugca ucacauuuaa aagcaucuca     1380

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     1440

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     1500

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc     1620

cccccccccc cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu       1678


<210>  6072
<211>  682
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (wt)

<400>  6072
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaag       60

ccucugcagc acuucugugu cugcugcuca cagcagcugc uuucagcccc caggggcuug      120

cucagccagu ugggauuaau acuucaacua ccugcugcua cagauuuauc aauaagaaaa      180

ucccuaagca gaggcuggag agcuacagaa ggaccaccag uagccacugu ccccgggaag      240

cuguaaucuu caagaccaaa cuggacaagg agaucugugc ugaccccaca cagaaguggg      300

uccaggacuu uaugaagcac cuggacaaga aaacccaaac uccaaagcug ugaggacuag      360

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      420

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      480

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      540

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc      660

ucuuuucaga gccaccagaa uu                                               682


<210>  6073
<211>  4006
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (wt)

<400>  6073
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcugc       60

ucacucuuau cauucuguug ccaguaguuu caaaauuuag uuuuguuagu cucucagcac      120

cgcagcacug gagcuguccu gaagguacuc ucgcaggaaa uggcaauucu acuugugugg      180

guccugcacc cuucuuaauu uucucccaug gaaauaguau cuuuaggauu gacacagaag      240

gaaccaauua ugagcaauug gugguggaug cuggugucuc agugaucaug gauuuucauu      300

auaaugagaa aagaaucuau uggguggauu uagaaagaca acuuuugcaa agaguuuuuc      360

ugaauggguc aaggcaagag agaguaugua auauagagaa aaauguuucu ggaauggcaa      420

uaaauuggau aaaugaagaa guuauuuggu caaaucaaca ggaaggaauc auuacaguaa      480

cagauaugaa aggaaauaau ucccacauuc uuuuaagugc uuuaaaauau ccugcaaaug      540

uagcaguuga uccaguagaa agguuuauau uuuggucuuc agagguggcu ggaagccuuu      600

auagagcaga ucucgauggu gugggaguga aggcucuguu ggagacauca gagaaaauaa      660

cagcuguguc auuggaugug cuugauaagc ggcuguuuug gauucaguac aacagagaag      720

gaagcaauuc ucuuauuugc uccugugauu augauggagg uucuguccac auuaguaaac      780

auccaacaca gcauaauuug uuugcaaugu cccuuuuugg ugaccguauc uucuauucaa      840

cauggaaaau gaagacaauu uggauagcca acaaacacac uggaaaggac augguuagaa      900

uuaaccucca uucaucauuu guaccacuug gugaacugaa aguagugcau ccacuugcac      960

aacccaaggc agaagaugac acuugggagc cugagcagaa acuuugcaaa uugaggaaag     1020

gaaacugcag cagcacugug ugugggcaag accuccaguc acacuugugc augugugcag     1080

agggauacgc ccuaagucga gaccggaagu acugugaaga uguuaaugaa ugugcuuuuu     1140

ggaaucaugg cuguacucuu ggguguaaaa acaccccugg auccuauuac ugcacgugcc     1200

cuguaggauu uguucugcuu ccugauggga aacgauguca ucaacuuguu uccuguccac     1260

gcaauguguc ugaaugcagc caugacugug uucugacauc agaagguccc uuauguuucu     1320

guccugaagg cucagugcuu gagagagaug ggaaaacaug uagcgguugu uccucacccg     1380

auaauggugg auguagccag cucugcguuc cucuuagccc aguauccugg gaaugugauu     1440

gcuuuccugg guaugaccua caacuggaug aaaaaagcug ugcagcuuca ggaccacaac     1500

cauuuuugcu guuugccaau ucucaagaua uucgacacau gcauuuugau ggaacagacu     1560

auggaacucu gcucagccag cagaugggaa ugguuuaugc ccuagaucau gacccugugg     1620

aaaauaagau auacuuugcc cauacagccc ugaaguggau agagagagcu aauauggaug     1680

guucccagcg agaaaggcuu auugaggaag gaguagaugu gccagaaggu cuugcugugg     1740

acuggauugg ccguagauuc uauuggacag acagagggaa aucucugauu ggaaggagug     1800

auuuaaaugg gaaacguucc aaaauaauca cuaaggagaa caucucucaa ccacgaggaa     1860

uugcuguuca uccaauggcc aagagauuau ucuggacuga uacagggauu aauccacgaa     1920

uugaaaguuc uucccuccaa ggccuuggcc gucugguuau agccagcucu gaucuaaucu     1980

ggcccagugg aauaacgauu gacuucuuaa cugacaaguu guacuggugc gaugccaagc     2040

agucugugau ugaaauggcc aaucuggaug guucaaaacg ccgaagacuu acccagaaug     2100

auguagguca cccauuugcu guagcagugu uugaggauua ugugugguuc ucagauuggg     2160

cuaugccauc aguaaugaga guaaacaaga ggacuggcaa agauagagua cgucuccaag     2220

gcagcaugcu gaagcccuca ucacugguug ugguucaucc auuggcaaaa ccaggagcag     2280

aucccugcuu auaucaaaac ggaggcugug aacauauuug caaaaagagg cuuggaacug     2340

cuugguguuc gugucgugaa gguuuuauga aagccucaga ugggaaaacg ugucuggcuc     2400

uggaugguca ucagcuguug gcaggaggug aaguugaucu aaagaaccaa guaacaccau     2460

uggacaucuu guccaagacu agagugucag aagauaacau uacagaaucu caacacaugc     2520

uaguggcuga aaucauggug ucagaucaag augacugugc uccuguggga ugcagcaugu     2580

augcucggug uauuucagag ggagaggaug ccacauguca guguuugaaa ggauuugcug     2640

gggauggaaa acuauguucu gauauagaug aaugugagau ggguguccca gugugccccc     2700

cugccuccuc caagugcauc aacaccgaag gugguuaugu cugccggugc ucagaaggcu     2760

accaaggaga ugggauucac ugucuugaua uugaugagug ccaacugggg gagcacagcu     2820

guggagagaa ugccagcugc acaaauacag agggaggcua uaccugcaug ugugcuggac     2880

gccugucuga accaggacug auuugcccug acucuacucc acccccucac cucagggaag     2940

augaccacca cuauuccgua agaaauagug acucugaaug uccccugucc cacgaugggu     3000

acugccucca ugauggugug ugcauguaua uugaagcauu ggacaaguau gcaugcaacu     3060

guguuguugg cuacaucggg gagcgauguc aguaccgaga ccugaagugg ugggaacugc     3120

gccacgcugg ccacgggcag cagcagaagg ucaucguggu ggcugucugc gugguggugc     3180

uugucaugcu gcuccuccug agccuguggg gggcccacua cuacaggacu cagaagcugc     3240

uaucgaaaaa cccaaagaau ccuuaugagg agucgagcag agaugugagg agucgcaggc     3300

cugcugacac ugaggauggg auguccucuu gcccucaacc uugguuugug guuauaaaag     3360

aacaccaaga ccucaagaau gggggucaac caguggcugg ugaggauggc caggcagcag     3420

augggucaau gcaaccaacu ucauggaggc aggagcccca guuaugugga augggcacag     3480

agcaaggcug cuggauucca guauccagug auaagggcuc cuguccccag guaauggagc     3540

ggagcuuuca uaugcccucc uaugggacac agacccuuga aggggguguc gagaagcccc     3600

auucucuccu aucagcuaac ccauuauggc aacaaagggc ccuggaccca ccacaccaaa     3660

uggagcugac ucagugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3720

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3780

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3840

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     3960

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    4006


<210>  6074
<211>  892
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (wt)

<400>  6074
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaccg       60

cggggaggag gauggagaug cucugugccg gcaggguccc ugcgcugcug cucugccugg      120

guuuccaucu ucuacaggca guccucagua caacugugau uccaucaugu aucccaggag      180

aguccaguga uaacugcaca gcuuuaguuc agacagaaga caauccacgu guggcucaag      240

ugucaauaac aaaguguagc ucugacauga auggcuauug uuugcaugga cagugcaucu      300

aucuggugga caugagucaa aacuacugca gaugugaagu ggguuauacu gguguccgau      360

gugaacacuu cuuuuuaacc guccaccaac cuuuaagcaa agaauaugug gcuuugaccg      420

ugauucuuau uauuuuguuu cuuaucacag ucgucgguuc cacauauuau uucugcagau      480

gguacagaaa ucgaaaaagu aaagaaccaa agaaggaaua ugagagaguu accucagggg      540

auccagaguu gccgcaaguc ugaggacuag ugcaucacau uuaaaagcau cucagccuac      600

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      660

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      720

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc      840

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu              892


<210>  6075
<211>  1249
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (wt)

<400>  6075
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggugg       60

gugugggggg uggagaugua gaagauguga cgccgcggcc cggcgggugc cagauuagcg      120

gacgcggugc ccgcgguugc aacgggaucc cgggcgcugc agcuugggag gcggcucucc      180

ccaggcggcg uccgcggaga cacccauccg ugaaccccag gucccgggcc gccggcucgc      240

cgcgcaccag gggccggcgg acagaagaac ggccgagcgg cucgaggcug ggggaccgcg      300

ggcgcggccg cgcgcugccg ggcgggaggc uggggggccg gggccggggc cgugccccgg      360

agcgggucgg aggccggggc cggggccggg ggacggcggc uccccgcgcg gcuccagcgg      420

cucggggauc ccggccgggc cccgcaggga ccauggcagc cgggagcauc accacgcugc      480

ccgccuugcc cgaggauggc ggcagcggcg ccuucccgcc cggccacuuc aaggacccca      540

agcggcugua cugcaaaaac gggggcuucu uccugcgcau ccaccccgac ggccgaguug      600

acgggguccg ggaaaagagc gacccucaca ucaagcuaca acuucaagca gaagagagag      660

gaguuguguc uaucaaagga gugugugcua accguuaccu ggcuaugaag gaagauggaa      720

gauuacuggc uucuaaaugu guuacggaug aguguuucuu uuuugaacga uuggaaucua      780

auaacuacaa uacuuaccgg ucaaggaaau acaccaguug guauguggca cugaaacgaa      840

cugggcagua uaaacuugga uccaaaacag gaccugggca gaaagcuaua cuuuuucuuc      900

caaugucugc uaagagcuga ggacuagugc aucacauuua aaagcaucuc agccuaccau      960

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     1020

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     1080

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     1140

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     1200

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 1249


<210>  6076
<211>  967
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (wt)

<400>  6076
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcaca       60

aauggauacu gacauggauc cugccaacuu ugcucuacag aucaugcuuu cacauuaucu      120

gucuaguggg uacuauaucu uuagcuugca augacaugac uccagagcaa auggcuacaa      180

augugaacug uuccagcccu gagcgacaca caagaaguua ugauuacaug gaaggagggg      240

auauaagagu gagaagacuc uucugucgaa cacaguggua ccugaggauc gauaaaagag      300

gcaaaguaaa agggacccaa gagaugaaga auaauuacaa uaucauggaa aucaggacag      360

uggcaguugg aauuguggca aucaaagggg uggaaaguga guucuaucuu gcaaugaaca      420

aggaaggaaa acucuaugca aagaaagaau gcaaugaaga uuguaacuuc aaagaacuaa      480

uucuggaaaa ccauuacaac acauaugcau cagcuaaaug gacacacaac ggaggggaaa      540

uguuuguugc cuuaaaucaa aaggggauuc cuguaagagg aaaaaaaacg aagaaagaac      600

aaaaaacagc ccacuuucuu ccuauggcaa uaacuuaagg acuagugcau cacauuuaaa      660

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc      720

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua      780

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac      960

cagaauu                                                                967


<210>  6077
<211>  2569
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (wt)

<400>  6077
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguggg       60

ugaccaaacu ccugccagcc cugcugcugc agcauguccu ccugcaucuc cuccugcucc      120

ccaucgccau ccccuaugca gagggacaaa ggaaaagaag aaauacaauu caugaguuca      180

aaaaaucagc aaagacuacc cuaaucaaaa uagauccagc acugaagaua aaaaccaaaa      240

aagugaauac ugcagaccaa ugugcuaaua gauguacuag gaauaaagga cuuccauuca      300

cuugcaaggc uuuuguuuuu gauaaagcaa gaaaacaaug ccucugguuc cccuucaaua      360

gcaugucaag uggagugaaa aaagaauuug gccaugaauu ugaccucuau gaaaacaaag      420

acuacauuag aaacugcauc auugguaaag gacgcagcua caagggaaca guaucuauca      480

cuaagagugg caucaaaugu cagcccugga guuccaugau accacacgaa cacagcuuuu      540

ugccuucgag cuaucggggu aaagaccuac aggaaaacua cugucgaaau ccucgagggg      600

aagaaggggg acccuggugu uucacaagca auccagaggu acgcuacgaa gucugugaca      660

uuccucagug uucagaaguu gaaugcauga ccugcaaugg ggagaguuau cgaggucuca      720

uggaucauac agaaucaggc aagauuuguc agcgcuggga ucaucagaca ccacaccggc      780

acaaauucuu gccugaaaga uaucccgaca agggcuuuga ugauaauuau ugccgcaauc      840

ccgauggcca gccgaggcca uggugcuaua cucuugaccc ucacacccgc ugggaguacu      900

gugcaauuaa aacaugcgcu gacaauacua ugaaugacac ugauguuccu uuggaaacaa      960

cugaaugcau ccaaggucaa ggagaaggcu acaggggcac ugucaauacc auuuggaaug     1020

gaaucccaug ucagcguugg gauucucagu auccucacga gcaugacaug acuccugaaa     1080

auuucaagug caaggaccua cgagaaaauu acugccgaaa uccagauggg ucugaaucac     1140

ccugguguuu uaccacugau ccaaacaucc gaguuggcua cugcucccaa auuccaaacu     1200

gugauauguc acauggacaa gauuguuauc gugggaaugg caaaaauuau augggcaacu     1260

uaucccaaac aagaucugga cuaacauguu caauguggga caagaacaug gaagacuuac     1320

aucgucauau cuucugggaa ccagaugcaa guaagcugaa ugagaauuac ugccgaaauc     1380

cagaugauga ugcucaugga cccuggugcu acacgggaaa uccacucauu ccuugggauu     1440

auugcccuau uucucguugu gaaggugaua ccacaccuac aauagucaau uuagaccauc     1500

ccguaauauc uugugccaaa acgaaacaau ugcgaguugu aaaugggauu ccaacacgaa     1560

caaacauagg auggaugguu aguuugagau acagaaauaa acauaucugc ggaggaucau     1620

ugauaaagga gaguuggguu cuuacugcac gacaguguuu cccuucucga gacuugaaag     1680

auuaugaagc auggcuugga auccaugaug uccacggaag aggagaugag aaaugcaaac     1740

agguucucaa uguuucccag cugguauaug gcccugaagg aucagaucug guuuuaauga     1800

agcuggccag gccugcuguc cuggaugauu uuguuaguac gauugauuua ccuaauuaug     1860

gaugcacaau uccugaaaag accaguugca guguuuaugg cuggggcuac acuggauuga     1920

ucaacuauga uggccuauua cgaguggcac aucucuauau aaugggaaau gagaaaugca     1980

gccagcauca ucgagggaag gugacucuga augagucuga aauaugugcu ggggcugaaa     2040

agauuggauc aggaccaugu gagggggauu augguggccc acuuguuugu gagcaacaua     2100

aaaugagaau gguucuuggu gucauuguuc cuggucgugg augugccauu ccaaaucguc     2160

cugguauuuu uguccgagua gcauauuaug caaaauggau acacaaaauu auuuuaacau     2220

auaagguacc acagucauag ggacuagugc aucacauuua aaagcaucuc agccuaccau     2280

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2340

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2400

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc     2520

cccccccccc cccccccccc caaaggcucu uuucagagcc accagaauu                 2569


<210>  6078
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (wt)

<400>  6078
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aagccgcggc gaucggcauc gaccugggca ccaccuacuc cugcgugggg guguuccaac      120

acggcaaggu ggagaucauc gccaacgacc agggcaaccg caccaccccc agcuacgugg      180

ccuucacgga caccgagcgg cucaucgggg augcggccaa gaaccaggug gcgcugaacc      240

cgcagaacac cguguuugac gcgaagcggc ugauuggccg caaguucggc gacccggugg      300

ugcagucgga caugaagcac uggccuuucc aggugaucaa cgacggagac aagcccaagg      360

ugcaggucag cuacaagggg gagaccaagg cauucuaccc cgaggagauc ucguccaugg      420

ugcugaccaa gaugaaggag aucgccgagg cguaccuggg cuacccggug accaacgcgg      480

ugaucaccgu gccggccuac uucaacgacu cgcagcgcca ggccaccaag gaugcgggug      540

ugaucgcggg gcucaacgug cugcggauca ucaacgagcc cacggccgcc gccaucgccu      600

acggccugga cagaacgggc aagggggagc gcaacgugcu caucuuugac cugggcgggg      660

gcaccuucga cguguccauc cugacgaucg acgacggcau cuucgaggug aaggccacgg      720

ccggggacac ccaccugggu ggggaggacu uugacaacag gcuggugaac cacuucgugg      780

aggaguucaa gagaaaacac aagaaggaca ucagccagaa caagcgagcc gugaggcggc      840

ugcgcaccgc cugcgagagg gccaagagga cccugucguc cagcacccag gccagccugg      900

agaucgacuc ccuguuugag ggcaucgacu ucuacacguc caucaccagg gcgagguucg      960

aggagcugug cuccgaccug uuccgaagca cccuggagcc cguggagaag gcucugcgcg     1020

acgccaagcu ggacaaggcc cagauucacg accugguccu ggucgggggc uccacccgca     1080

uccccaaggu gcagaagcug cugcaggacu ucuucaacgg gcgcgaccug aacaagagca     1140

ucaaccccga cgaggcugug gccuacgggg cggcggugca ggcggccauc cugauggggg     1200

acaaguccga gaacgugcag gaccugcugc ugcuggacgu ggcuccccug ucgcuggggc     1260

uggagacggc cggaggcgug augacugccc ugaucaagcg caacuccacc auccccacca     1320

agcagacgca gaucuucacc accuacuccg acaaccaacc cggggugcug auccaggugu     1380

acgagggcga gagggccaug acgaaagaca acaaucuguu ggggcgcuuc gagcugagcg     1440

gcaucccucc ggcccccagg ggcgugcccc agaucgaggu gaccuucgac aucgaugcca     1500

acggcauccu gaacgucacg gccacggaca agagcaccgg caaggccaac aagaucacca     1560

ucaccaacga caagggccgc cugagcaagg aggagaucga gcgcauggug caggaggcgg     1620

agaaguacaa agcggaggac gaggugcagc gcgagagggu gucagccaag aacgcccugg     1680

aguccuacgc cuucaacaug aaaagcgccg uggaggauga ggggcucaag ggcaagauca     1740

gcgaggcgga caagaagaag gugcuggaca agugucaaga ggucaucucg uggcuggacg     1800

ccaacaccuu ggccgagaag gacgaguuug agcacaagag gaaggagcug gagcaggucu     1860

guaaccccau caucagcgga cuguaccagg gugccggugg ucccgggccu gggggcuucg     1920

gggcucaggg ucccaaggga gggucugggu caggccccac cauugaggag guagauuagg     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  6079
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (wt)

<400>  6079
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcca       60

aagccgcggc gaucggcauc gaccugggca ccaccuacuc cugcgugggg guguuccaac      120

acggcaaggu ggagaucauc gccaacgacc agggcaaccg caccaccccc agcuacgugg      180

ccuucacgga caccgagcgg cucaucgggg augcggccaa gaaccaggug gcgcugaacc      240

cgcagaacac cguguuugac gcgaagcggc ugauuggccg caaguucggc gacccggugg      300

ugcagucgga caugaagcac uggccuuucc aggugaucaa cgacggagac aagcccaagg      360

ugcaggucag cuacaagggg gagaccaagg cauucuaccc cgaggagauc ucguccaugg      420

ugcugaccaa gaugaaggag aucgccgagg cguaccuggg cuacccggug accaacgcgg      480

ugaucaccgu gccggccuac uucaacgacu cgcagcgcca ggccaccaag gaugcgggug      540

ugaucgcggg gcucaacgug cugcggauca ucaacgagcc cacggccgcc gccaucgccu      600

acggccugga cagaacgggc aagggggagc gcaacgugcu caucuuugac cugggcgggg      660

gcaccuucga cguguccauc cugacgaucg acgacggcau cuucgaggug aaggccacgg      720

ccggggacac ccaccugggu ggggaggacu uugacaacag gcuggugaac cacuucgugg      780

aggaguucaa gagaaaacac aagaaggaca ucagccagaa caagcgagcc gugaggcggc      840

ugcgcaccgc cugcgagagg gccaagagga cccugucguc cagcacccag gccagccugg      900

agaucgacuc ccuguuugag ggcaucgacu ucuacacguc caucaccagg gcgagguucg      960

aggagcugug cuccgaccug uuccgaagca cccuggagcc cguggagaag gcucugcgcg     1020

acgccaagcu ggacaaggcc cagauucacg accugguccu ggucgggggc uccacccgca     1080

uccccaaggu gcagaagcug cugcaggacu ucuucaacgg gcgcgaccug aacaagagca     1140

ucaaccccga cgaggcugug gccuacgggg cggcggugca ggcggccauc cugauggggg     1200

acaaguccga gaacgugcag gaccugcugc ugcuggacgu ggcuccccug ucgcuggggc     1260

uggagacggc cggaggcgug augacugccc ugaucaagcg caacuccacc auccccacca     1320

agcagacgca gaucuucacc accuacuccg acaaccaacc cggggugcug auccaggugu     1380

acgagggcga gagggccaug acgaaagaca acaaucuguu ggggcgcuuc gagcugagcg     1440

gcaucccucc ggcccccagg ggcgugcccc agaucgaggu gaccuucgac aucgaugcca     1500

acggcauccu gaacgucacg gccacggaca agagcaccgg caaggccaac aagaucacca     1560

ucaccaacga caagggccgc cugagcaagg aggagaucga gcgcauggug caggaggcgg     1620

agaaguacaa agcggaggac gaggugcagc gcgagagggu gucagccaag aacgcccugg     1680

aguccuacgc cuucaacaug aaaagcgccg uggaggauga ggggcucaag ggcaagauca     1740

gcgaggcgga caagaagaag guucuggaca agugucaaga ggucaucucg uggcuggacg     1800

ccaacaccuu ggccgagaag gacgaguuug agcacaagag gaaggagcug gagcaggucu     1860

guaaccccau caucagcgga cuguaccagg gugccggugg ucccgggccu ggcggcuucg     1920

gggcucaggg ucccaaggga gggucugggu caggcccuac cauugaggag guggauuagg     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  6080
<211>  2308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (wt)

<400>  6080
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcua       60

cugccaaggg aaucgccaua ggcaucgacc ugggcaccac cuacuccugu gugggggugu      120

uccagcacgg caagguggag aucaucgcca acgaccaggg caaccgcacc acccccagcu      180

acguggccuu cacagacacc gagcggcuca uuggggaugc ggccaagaac cagguagcaa      240

ugaaucccca gaacacuguu uuugaugcua aacgucugau cggcaggaaa uuuaaugauc      300

cuguuguaca agcagauaug aaacuuuggc cuuuucaagu gauuaaugaa ggaggcaagc      360

ccaaaguccu uguguccuac aaaggggaga auaaagcauu cuacccugag gaaaucucuu      420

cgaugguauu gacuaaguug aaggagacug cugaggccuu uuugggccac ccugucacca      480

augcagugau uaccgugcca gccuauuuca augacucuca acgucaggcu acuaaggaug      540

caggagugau ugcuggacuu aaugugcuaa gaaucaucaa ugagcccacg gcugcugcca      600

uugccuaugg uuuagauaaa ggaggucaag gagaacgaca uguccugauu uuugaucugg      660

guggaggcac auuugaugug ucaauucuga ccauagauga ugggauuuuu gagguaaagg      720

ccacugcugg ggacacucac cugggugggg aggacuuuga caacaggcuu gugagccacu      780

ucguggagga guucaagagg aaacacaaaa aggacaucag ccagaacaag cgagccguga      840

ggcggcugcg caccgccugc gagagggcca agaggacccu gucguccagc acccaggcca      900

accuagaaau ugauucacuu uaugaaggca uugacuucua uacauccauc accagagcuc      960

gauuugaaga guugugugca gaccuguuua gggguacccu ggagccugua gaaaaagcgc     1020

uucgggaugc caagauggau aaggcuaaaa uccaugacau uguuuuagua gggggcucca     1080

cccgcauccc caaggugcag cggcugcuuc aggacuacuu caauggacgu gaucucaaca     1140

agagcaucaa cccugaugag gccguagcau auggggcugc gguacaagca gccauccuga     1200

ugggggacaa gucugagaag guacaggacc ugcugcugcu ggacguggcu ccccuguccc     1260

uggggcugga gacggcuggg ggcgugauga cugcccugau aaagcgcaac uccaccaucc     1320

ccaccaagca gacacagauu uucaccaccu acucugacaa ccaacccggg gugcugaucc     1380

agguguauga gggcgagagg gccaugacaa aggacaacaa ccugcugggg cgguuugacc     1440

ugacuggaau cccuccagca cccaggggag uuccucagau cgaggugacg uuugacauug     1500

augccaaugg uauucucaau gucacagcca cggacaagag caccggcaag gugaacaaga     1560

ucaccaucac caaugacaag ggccgccuga gcaaggagga gauugagcgc augguucugg     1620

augcugagaa auauaaagcu gaagaugagg uccagaggga gaaaauugcu gcaaagaaug     1680

ccuuagaauc cuaugcuuuu aacaugaaga guguugugag ugaugaaggu uugaagggca     1740

agauuaguga gucugauaaa aauaaaauau uggauaaaug caacgagcuc cuuucguggc     1800

uggaggucaa ucaacuggca gagaaagaug aguuugauca uaagagaaag gaauuggagc     1860

agauguguaa cccuaucauc acaaaacucu accaaggagg augcacuggg ccugccugcg     1920

gaacagggua ugugccugga aggccugcca caggccccac aauugaagaa guagauuaag     1980

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     2040

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     2100

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     2160

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     2280

aaaggcucuu uucagagcca ccagaauu                                        2308


<210>  6081
<211>  2905
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (wt)

<400>  6081
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucgg       60

uggugggcau agaccugggc uuccagagcu gcuacgucgc uguggcccgc gccggcggca      120

ucgagacuau cgcuaaugag uauagcgacc gcugcacgcc ggcuugcauu ucuuuugguc      180

cuaagaaucg uucaauugga gcagcagcua aaagccaggu aauuucuaau gcaaagaaca      240

caguccaagg auuuaaaaga uuccauggcc gagcauucuc ugauccauuu guggaggcag      300

aaaaaucuaa ccuugcauau gauauugugc aguugccuac aggauuaaca gguauaaagg      360

ugacauauau ggaggaagaa cgaaauuuua ccacugagca agugacugcc augcuuuugu      420

ccaaacugaa ggagacagcc gaaaguguuc uuaagaagcc uguaguugac uguguuguuu      480

cgguuccuug uuucuauacu gaugcagaaa gacgaucagu gauggaugca acacagauug      540

cuggucuuaa uugcuugcga uuaaugaaug aaaccacugc aguugcucuu gcauauggaa      600

ucuauaagca ggaucuuccu gccuuagaag agaaaccaag aaauguaguu uuuguagaca      660

ugggccacuc ugcuuaucaa guuucuguau gugcauuuaa uagaggaaaa cugaaaguuc      720

uggccacugc auuugacacg acauugggag guagaaaauu ugaugaagug uuaguaaauc      780

acuucuguga agaauuuggg aagaaauaca agcuagacau uaaguccaaa auccgugcau      840

uauuacgacu cucucaggag ugugagaaac ucaagaaauu gaugagugca aaugcuucag      900

aucucccuuu gagcauugaa uguuuuauga augauguuga uguaucugga acuaugaaua      960

gaggcaaauu ucuggagaug ugcaaugauc ucuuagcuag aguggagcca ccacuucgua     1020

guguuuugga acaaaccaag uuaaagaaag aagauauuua ugcaguggag auaguuggug     1080

gugcuacacg aaucccugcg guaaaagaga agaucagcaa auuuuucggu aaagaacuua     1140

guacaacauu aaaugcugau gaagcuguca cucgaggcug ugcauugcag ugugccaucu     1200

uaucgccugc uuucaaaguc agagaauuuu cuaucacuga uguaguacca uauccaauau     1260

cucugagaug gaacucucca gcugaagaag ggucaaguga cugugaaguc uuuuccaaaa     1320

aucaugcugc uccuuucucu aaaguucuua cauuuuauag aaaggaaccu uucacucuug     1380

aggccuacua cagcucuccu caggauuugc ccuauccaga uccugcuaua gcucaguuuu     1440

caguucagaa agucacuccu cagucugaug gcuccaguuc aaaagugaaa gucaaaguuc     1500

gaguaaaugu ccauggcauu uucagugugu ccagugcauc uuuaguggag guucacaagu     1560

cugaggaaaa ugaggagcca auggaaacag aucagaaugc aaaggaggaa gagaagaugc     1620

aaguggacca ggaggaacca cauguugaag aacaacagca gcagacacca gcagaaaaua     1680

aggcagaguc ugaagaaaug gagaccucuc aagcuggauc caaggauaaa aagauggacc     1740

aaccacccca agccaagaag gcaaaaguga agaccaguac uguggaccug ccaaucgaga     1800

aucagcuauu auggcagaua gacagagaga ugcucaacuu guacauugaa aaugagggua     1860

agaugaucau gcaggauaaa cuggagaagg agcggaauga ugcuaagaac gcaguggagg     1920

aauaugugua ugaaaugaga gacaagcuga guggugaaua ugagaaguuu gugagugaag     1980

augaucguaa caguuuuacu uugaaacugg aagauacuga aaauugguug uaugaggaug     2040

gagaagacca gccaaagcaa guuuauguug auaaguuggc ugaauuaaaa aaucuagguc     2100

aaccuauuaa gauacguuuc caggaaucug aagaacgacc aaaauuauuu gaagaacuag     2160

ggaaacagau ccaacaguau augaaaauaa ucagcucuuu caaaaacaag gaggaccagu     2220

augaucauuu ggaugcugcu gacaugacaa agguagaaaa aagcacaaau gaagcaaugg     2280

aguggaugaa uaacaagcua aaucugcaga acaagcagag uuugaccaug gauccaguug     2340

ucaagucaaa agagauugaa gcuaaaauua aggagcugac aaguacuugu agcccuauaa     2400

uuucaaagcc caaacccaaa guggaaccuc caaaagagga acaaaaaaau gcagagcaga     2460

auggaccagu ggauggacaa ggagacaacc caggccccca ggcugcugag caggguacag     2520

acacagcugu gccuucggau ucagacaaga agcugccuga aauggacauu gauugaggac     2580

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2640

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2700

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2760

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa     2880

ggcucuuuuc agagccacca gaauu                                           2905


<210>  6082
<211>  2902
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (wt)

<400>  6082
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucug       60

ugguuggcau ugaccucggc uuucucaacu gcuacauugc ugucgcgaga aguggcggca      120

ucgagaccau cgccaaugag uacagcgaca gguguacccc ggccuguaua ucauugggau      180

caagaacucg agccauugga aaugcagcaa agagccagau agucacgaac guaagaaaua      240

caauucaugg cuucaaaaag cugcaugggc gaucauuuga ugaucccauu gugcaaacug      300

aaaggaucag gcuucccuau gaacugcaga aaaugccuaa uggaagugca ggaguuaagg      360

ugcgguacuu agaggaagag agaccuuuug caauugagca aguuacugga augcuguuag      420

ccaagcugaa agagacuuca gaaaaugcuu ugaagaaacc aguggcugac ugugugauuu      480

caauuccuag cuuuuuuacu gaugccgaga gaagaucugu gauggcugca gcccagguug      540

caggcuuaaa uuguuuaagg uugaugaaug aaacuacugc aguugcacug gcguauggaa      600

uuuauaaaca ggaucuuccc ccauuagaug agaaaccaag aaauguagua uuuauugaua      660

ugggacauuc ugccuaucag gucuugguuu gugcuuuuaa caaaggaaaa cuuaaagucu      720

uggcuacuac cuuugaucca uauuugggug gcaggaacuu ugaugaggcu uuaguagacu      780

acuucuguga ugaguucaag accaaauaua agauaaaugu gaaagaaaac ucucgggccu      840

uguugcguuu auaucaggaa ugugaaaaac uaaagaagcu aaugagugca aaugcaucag      900

aucuuccauu gaacauugag uguuucauga augaccuuga uguuucuagu aaaaugaaca      960

gggcucaauu ugaacaacug ugugcuuccc uuuuggccag gguugaacca ccuuuaaaag     1020

caguaaugga acaagcuaac uuacaacgug aagacauuag uaguauagaa auuguaggag     1080

gagcaacacg aaucccugca gugaaagaac aaaucacuaa auucuuucuu aaagacauaa     1140

guaccacauu aaaugcugau gaagcuguug caagaggaug ugcguuacag ugugcgauuc     1200

ucucaccagc auuuaaagug cgugaauuuu ccauaacaga ccuuguuccc uauucaauca     1260

cauuaaggug gaagaccucu uuugaagaug gaagugggga augugaaguu uucuguaaga     1320

accauccugc cccauucuca aaagucauua cuuuccacaa gaaggaacca uuugaacuag     1380

aagcauuuua uacuaauuua caugaagugc cuuauccuga ugcaagaauu gggagcuuca     1440

cuauucagaa uguuuuucca cagucugaug gugauaguuc caaagugaag guuaaaguuc     1500

guguuaacau ccauggaauc uucagugugg cuagcgcauc aguaauugag aagcaaaauu     1560

uggaaggcga ucacagugau gcuccaaugg agacagaaac uucauuuaaa aaugaaaaca     1620

aagauaauau ggauaaaaug cagguugauc aagaagaagg gcaucaaaaa ugucaugcug     1680

aacacacucc agaagaggaa auugaucaua caggagccaa aacaaaguca gcugucucag     1740

acaaacaaga ccgauuaaau cagacacuua aaaaaggaaa agucaaaagu auugaucuac     1800

cgauccagag uagccuaugu agacaacuag gccaagaucu ucucaacagc uacauugaaa     1860

augaggggaa gaugaucaug caagauaagu uagagaaaga aagaaaugau gcuaagaaug     1920

ccguugaaga auauguauau gauuuuagag acaggcuggg cacugucuau gaaaaauuca     1980

ucacuccaga agacuugagu aaacugucug caguauugga agacacagaa aauuggcuuu     2040

augaagacgg agaggaccaa ccuaaacaag uuuaugugga uaagcugcaa gaacuaaaga     2100

aauacggcca gccuauucaa augaaguaca uggagcauga agagagacca aaagccuuaa     2160

augacuuggg aaaaaagauc caacuuguca ugaaagugau agaagcauau agaaacaagg     2220

augaaagaua ugaucaucug gauccuacug aaauggaaaa gguugaaaaa uguaucagug     2280

augccaugag uuggcugaau aguaagauga augcacagaa caaacuaagu cucacucaag     2340

auccuguggu aaaaguuuca gaaauaguag caaagucaaa ggaacuggau aauuucugua     2400

accccaucau uuacaagccc aaaccaaaag cagaaguucc ugaagacaaa ccaaaagcua     2460

auagugaaca caauggccca auggauggac agaguggaac ugaaacuaaa ucagauucaa     2520

caaaagacag cucacagcau acuaaauccu cuggagagau ggaaguggac uaaggacuag     2580

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2640

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2700

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2760

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2880

ucuuuucaga gccaccagaa uu                                              2902


<210>  6083
<211>  2347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (wt)

<400>  6083
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaagc       60

ucucccuggu ggccgcgaug cugcugcugc ucagcgcggc gcgggccgag gaggaggaca      120

agaaggagga cgugggcacg guggucggca ucgaccuggg gaccaccuac uccugcgucg      180

gcguguucaa gaacggccgc guggagauca ucgccaacga ucagggcaac cgcaucacgc      240

cguccuaugu cgccuucacu ccugaagggg aacgucugau uggcgaugcc gccaagaacc      300

agcucaccuc caaccccgag aacacggucu uugacgccaa gcggcucauc ggccgcacgu      360

ggaaugaccc gucugugcag caggacauca aguucuugcc guucaaggug guugaaaaga      420

aaacuaaacc auacauucaa guugauauug gaggugggca aacaaagaca uuugcuccug      480

aagaaauuuc ugccaugguu cucacuaaaa ugaaagaaac cgcugaggcu uauuugggaa      540

agaagguuac ccaugcaguu guuacuguac cagccuauuu uaaugaugcc caacgccaag      600

caaccaaaga cgcuggaacu auugcuggcc uaaauguuau gaggaucauc aacgagccua      660

cggcagcugc uauugcuuau ggccuggaua agagggaggg ggagaagaac auccuggugu      720

uugaccuggg uggcggaacc uucgaugugu cucuucucac cauugacaau ggugucuucg      780

aaguuguggc cacuaaugga gauacucauc uggguggaga agacuuugac cagcguguca      840

uggaacacuu caucaaacug uacaaaaaga agacgggcaa agaugucagg aaagacaaua      900

gagcugugca gaaacuccgg cgcgagguag aaaaggccaa acgggcccug ucuucucagc      960

aucaagcaag aauugaaauu gaguccuucu augaaggaga agacuuuucu gagacccuga     1020

cucgggccaa auuugaagaa cucaacaugg aucuguuccg gucuacuaug aagcccgucc     1080

agaaaguguu ggaagauucu gauuugaaga agucugauau ugaugaaauu guucuuguug     1140

guggcucgac ucgaauccca aagauucagc aacugguuaa agaguucuuc aauggcaagg     1200

aaccaucccg uggcauaaac ccagaugaag cuguagcgua uggugcugcu guccaggcug     1260

gugugcucuc uggugaucaa gauacaggug accugguacu gcuugaugua uguccccuua     1320

cacuugguau ugaaacugug ggagguguca ugaccaaacu gauuccaagg aacacagugg     1380

ugccuaccaa gaagucucag aucuuuucua cagcuucuga uaaucaacca acuguuacaa     1440

ucaaggucua ugaaggugaa agaccccuga caaaagacaa ucaucuucug gguacauuug     1500

aucugacugg aaucccuccu gcuccucgug gggucccaca gauugaaguc accuuugaga     1560

uagaugugaa ugguauucuu cgagugacag cugaagacaa ggguacaggg aacaaaaaua     1620

agaucacaau caccaaugac cagaaucgcc ugacaccuga agaaaucgaa aggaugguua     1680

augaugcuga gaaguuugcu gaggaagaca aaaagcucaa ggagcgcauu gauacuagaa     1740

augaguugga aagcuaugcc uauucucuaa agaaucagau uggagauaaa gaaaagcugg     1800

gagguaaacu uuccucugaa gauaaggaga ccauggaaaa agcuguagaa gaaaagauug     1860

aauggcugga aagccaccaa gaugcugaca uugaagacuu caaagcuaag aagaaggaac     1920

uggaagaaau uguucaacca auuaucagca aacucuaugg aagugcaggc ccucccccaa     1980

cuggugaaga ggauacagca gaaaaagaug aguuguaggg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     2340

cagaauu                                                               2347


<210>  6084
<211>  2314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (wt)

<400>  6084
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

ccccacggga gcucgcggug ggcaucgacc ugggcaccac cuacucgugc gugggcgugu      120

uucagcaggg ccgcguggag auccuggcca acgaccaggg caaccgcacc acgcccagcu      180

acguggccuu caccgacacc gagcggcugg ucggggacgc ggccaagagc caggcggccc      240

ugaaccccca caacaccgug uucgaugcca agcggcugau cgggcgcaag uucgcggaca      300

ccacggugca gucggacaug aagcacuggc ccuuccgggu ggugagcgag ggcggcaagc      360

ccaaggugcg cguaugcuac cgcggggagg acaagacguu cuaccccgag gagaucucgu      420

ccauggugcu gagcaagaug aaggagacgg ccgaggcgua ccugggccag cccgugaagc      480

acgcagugau caccgugccc gccuauuuca augacucgca gcgccaggcc accaaggacg      540

cgggggccau cgcggggcuc aacguguugc ggaucaucaa ugagcccacg gcagcugcca      600

ucgccuaugg gcuggaccgg cggggcgcgg gagagcgcaa cgugcucauu uuugaccugg      660

gugggggcac cuucgaugug ucgguucucu ccauugacgc uggugucuuu gaggugaaag      720

ccacugcugg agauacccac cugggaggag aggacuucga caaccggcuc gugaaccacu      780

ucauggaaga guuccggcgg aagcauggga aggaccugag cgggaacaag cgugcccugc      840

gcaggcugcg cacagccugu gagcgcgcca agcgcacccu guccuccagc acccaggcca      900

cccuggagau agacucccug uucgagggcg uggacuucua cacguccauc acucgugccc      960

gcuuugagga acugugcuca gaccucuucc gcagcacccu ggagccggug gagaaggccc     1020

ugcgggaugc caagcuggac aaggcccaga uucaugacgu cguccuggug gggggcucca     1080

cacgcauccc caaggugcag aaguugcugc aggacuucuu caacggcaag gagcugaaca     1140

agagcaucaa cccugaugag gcuguggccu auggggcugc ugugcaggcg gccguguuga     1200

ugggggacaa augugagaaa gugcaggauc uccugcugcu ggauguggcu ccccugucuc     1260

uggggcugga gacagcagga ggggugauga ccacgcugau ccagaggaac gccacuaucc     1320

ccaccaagca gacccagacu uucaccaccu acucggacaa ccagccuggg gucuucaucc     1380

agguguauga gggugagagg gccaugacca aggacaacaa ccugcugggg cguuuugaac     1440

ucaguggcau cccuccugcc ccacguggag ucccccagau agaggugacu uuugacauug     1500

augcuaaugg cauccugagc gugacagcca cugacaggag cacagguaag gcuaacaaga     1560

ucaccaucac caaugacaag ggccggcuga gcaaggagga gguggagagg augguucaug     1620

aagccgagca guacaaggcu gaggaugagg cccagaggga cagaguggcu gccaaaaacu     1680

cgcuggaggc ccaugucuuc caugugaaag guucuuugca agaggaaagc cuuagggaca     1740

agauucccga agaggacagg cgcaaaaugc aagacaagug ucgggaaguc cuugccuggc     1800

uggagcacaa ccagcuggca gagaaggagg aguaugagca ucagaagagg gagcuggagc     1860

aaaucugucg ccccaucuuc uccaggcucu auggggggcc uggugucccu gggggcagca     1920

guuguggcac ucaagcccgc cagggggacc ccagcaccgg ccccaucauu gaggagguug     1980

auugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2040

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2100

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2160

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2280

ccccccaaag gcucuuuuca gagccaccag aauu                                 2314


<210>  6085
<211>  1486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (wt)

<400>  6085
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcagg       60

ccccacggga gcucgcggug ggcaucgacc ugggcaccac cuacucgugc gugggcgugu      120

uucagcaggg ccgcguggag auccuggcca acgaccaggg caaccgcacc acgcccagcu      180

acguggccuu caccgacacc gagcggcugg ucggggacgc ggccaagagc caggcggccc      240

ugaaccccca caacaccgug uucgaugcca agcggcugau cgggcgcaag uucgcggaca      300

ccacggugca gucggacaug aagcacuggc ccuuccaggu ggugagcgag ggcggcaagc      360

ccaaggugcg cguaugcuac cgcggggagg acaagacguu cuaccccgag gagaucucgu      420

ccauggugcu gagcaagaug aaggagacgg ccgaggcgua ccugggccag cccgugaagc      480

acgcagugau caccgugccc accuauuuca guaacucgca gcgccaggcc accaaggacg      540

cgggggccau cgcggggcuc aaggugcugc cgaucaucaa ugaggccacg gcagcagcca      600

ucgccuaugg gcuggaccgg cggggcgcgg gaaagcgcaa cgugcucauu uuugaccugg      660

gugggggcac cuucgaugug ucgguucucu ccauugacgc cggugucuuu gaggugaaag      720

ccacugcugg agauacccac cugggaggag aggacuucga caaccggcuc gugaaccacu      780

ucauggaaga guuccggcgg aagcauggga aggaccugag cgggaacaag cgugcccugc      840

gcaggcugcg cacagccugu gagcgcgcca agcgcacccc guccuccagc acccaggcca      900

cccuggagau agacucccug uucgagggcg uggacuucua caaguccauc acucgugccc      960

gcuuugagga acugugcuca gaccucuucc gcagcacccu ggagccggug gagaaggccc     1020

ugcgggaugc caagcuggac aaggcccaga uucaugacuu cguccugggg ggagggcucc     1080

acucgcaucc ccaaggugca gaaguugcug caggacuucu ucaacggcaa ggagcugaac     1140

aagagcauca acccugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1200

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1260

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1320

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1440

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1486


<210>  6086
<211>  2323
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (wt)

<400>  6086
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucca       60

agggaccugc aguugguauu gaucuuggca ccaccuacuc uugugugggu guuuuccagc      120

acggaaaagu cgagauaauu gccaaugauc agggaaaccg aaccacucca agcuaugucg      180

ccuuuacgga cacugaacgg uugaucggug augccgcaaa gaaucaaguu gcaaugaacc      240

ccaccaacac aguuuuugau gccaaacguc ugauuggacg cagauuugau gaugcuguug      300

uccagucuga uaugaaacau uggcccuuua ugguggugaa ugaugcuggc aggcccaagg      360

uccaaguaga auacaaggga gagaccaaga gcuucuaucc agaggaggug ucuucuaugg      420

uucugacaaa gaugaaggaa auugcagaag ccuaccuugg gaagacuguu accaaugcug      480

uggucacagu gccagcuuac uuuaaugacu cucagcguca ggcuaccaaa gaugcuggaa      540

cuauugcugg ucucaaugua cuuagaauua uuaaugagcc aacugcugcu gcuauugcuu      600

acggcuuaga caaaaagguu ggagcagaaa gaaacgugcu caucuuugac cugggaggug      660

gcacuuuuga ugugucaauc cucacuauug aggauggaau cuuugagguc aagucuacag      720

cuggagacac ccacuugggu ggagaagauu uugacaaccg aauggucaac cauuuuauug      780

cugaguuuaa gcgcaagcau aagaaggaca ucagugagaa caagagagcu guaagacgcc      840

uccguacugc uugugaacgu gcuaagcgua cccucucuuc cagcacccag gccaguauug      900

agaucgauuc ucucuaugaa ggaaucgacu ucuauaccuc cauuacccgu gcccgauuug      960

aagaacugaa ugcugaccug uuccguggca cccuggaccc aguagagaaa gcccuucgag     1020

augccaaacu agacaaguca cagauucaug auauuguccu gguugguggu ucuacucgua     1080

uccccaagau ucagaagcug cuccaagacu ucuucaaugg aaaagaacug aauaagagca     1140

ucaacccuga ugaagcuguu gcuuauggug cagcugucca ggcagccauc uugucuggag     1200

acaagucuga gaauguucaa gauuugcugc ucuuggaugu cacuccucuu ucccuuggua     1260

uugaaacugc ugguggaguc augacugucc ucaucaagcg uaauaccacc auuccuacca     1320

agcagacaca gaccuucacu accuauucug acaaccagcc uggugugcuu auucagguuu     1380

augaaggcga gcgugccaug acaaaggaua acaaccugcu uggcaaguuu gaacucacag     1440

gcauaccucc ugcaccccga gguguuccuc agauugaagu cacuuuugac auugaugcca     1500

augguauacu caaugucucu gcuguggaca agaguacggg aaaagagaac aagauuacua     1560

ucacuaauga caagggccgu uugagcaagg aagacauuga acguaugguc caggaagcug     1620

agaaguacaa agcugaagau gagaagcaga gggacaaggu gucauccaag aacucacuug     1680

aguccuaugc cuucaacaug aaagcaacug uugaagauga gaaacuucaa ggcaagauua     1740

acgaugagga caaacagaag auucuggaca aguguaauga aauuaucaac uggcuugaua     1800

agaaucagac ugcugagaag gaagaauuug aacaucaaca gaaagagcug gagaaaguuu     1860

gcaaccccau caucaccaag cuguaccaga gugcaggagg caugccagga ggaaugccug     1920

ggggauuucc ugguggugga gcuccucccu cugguggugc uuccucaggg cccaccauug     1980

aagagguuga uuaaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2040

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2100

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2160

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2280

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2323


<210>  6087
<211>  2422
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (wt)

<400>  6087
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugauaa       60

gugccagccg agcugcagca gcccgucucg ugggcgccgc agccucccgg ggcccuacgg      120

ccgcccgcca ccaggauagc uggaauggcc uuagucauga ggcuuuuaga cuuguuucaa      180

ggcgggauua ugcaucagaa gcaaucaagg gagcaguugu ugguauugau uuggguacua      240

ccaacuccug cguggcaguu auggaaggua aacaagcaaa ggugcuggag aaugccgaag      300

gugccagaac caccccuuca guuguggccu uuacagcaga uggugagcga cuuguuggaa      360

ugccggccaa gcgacaggcu gucaccaacc caaacaauac auuuuaugcu accaagcguc      420

ucauuggccg gcgauaugau gauccugaag uacagaaaga cauuaaaaau guucccuuua      480

aaauuguccg ugccuccaau ggugaugccu ggguugaggc ucaugggaaa uuguauucuc      540

cgagucagau uggagcauuu guguugauga agaugaaaga gacugcagaa aauuacuugg      600

ggcacacagc aaaaaaugcu gugaucacag ucccagcuua uuucaaugac ucgcagagac      660

aggccacuaa agaugcuggc cagauaucug gacugaaugu gcuucgggug auuaaugagc      720

ccacagcugc ugcucuugcc uauggucuag acaaaucaga agacaaaguc auugcuguau      780

augauuuagg ugguggaacu uuugauauuu cuauccugga aauucagaaa ggaguauuug      840

aggugaaauc cacaaauggg gauaccuucu uaggugggga agacuuugac caggccuugc      900

uacggcacau ugugaaggag uucaagagag agacaggggu ugauuugacu aaagacaaca      960

uggcacuuca gaggguacgg gaagcugcug aaaaggcuaa augugaacuc uccucaucug     1020

ugcagacuga caucaauuug cccuaucuua caauggauuc uucuggaccc aagcauuuga     1080

auaugaaguu gacccgugcu caauuugaag ggauugucac ugaucuaauc agaaggacua     1140

ucgcuccaug ccaaaaagcu augcaagaug cagaagucag caagagugac auaggagaag     1200

ugauucuugu ggguggcaug acuaggaugc ccaagguuca gcagacugua caggaucuuu     1260

uuggcagagc cccaaguaaa gcugucaauc cugaugaggc uguggccauu ggagcugcca     1320

uucagggagg uguguuggcc ggcgauguca cggaugugcu gcuccuugau gucacucccc     1380

ugucucuggg uauugaaacu cuaggaggug ucuuuaccaa acuuauuaau aggaauacca     1440

cuauuccaac caagaaaagc cagguauucu cuacugccgc ugauggucaa acgcaagugg     1500

aaauuaaagu gugucagggu gaaagagaga uggcuggaga caacaaacuc cuuggacagu     1560

uuacuuugau uggaauccca ccagccccuc guggaguucc ucagauugaa guuacauuug     1620

acauugaugc caaugggaua guacauguuu cugcuaaaga uaaaggcaca ggacgugagc     1680

agcagauugu aauccagucu ucugguggau uaagcaaaga ugauauugaa aauaugguua     1740

aaaaugcaga gaaauaugcu gaagaagacc ggcgaaagaa ggaacgaguu gaagcaguua     1800

auauggcuga aggaaucauu cacgacacag aaaccaagau ggaagaguuc aaggaccaau     1860

uaccugcuga ugagugcaac aagcugaaag aagagauuuc caaaaugagg gagcuccugg     1920

cuagaaaaga cagcgaaaca ggagaaaaua uuagacaggc agcauccucu cuucagcagg     1980

caucacugaa gcuguucgaa auggcauaca aaaagauggc aucugagcga gaaggcucug     2040

gaaguucugg cacuggggaa caaaaggaag aucaaaagga ggaaaaacag uaaggacuag     2100

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     2160

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     2220

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     2280

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     2400

ucuuuucaga gccaccagaa uu                                              2422


<210>  6088
<211>  2443
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (wt)

<400>  6088
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguugg       60

cugucccgga gaugggccug caggggcugu acaucggcuc cagcccggag cgguccccag      120

ugccuagccc acccggcucc ccgaggaccc aggaaagcug cggcauugcc ccccucacac      180

ccucgcaguc uccaaaaccc gagguccgag ccccccagca ggccuccuuc ucuguggugg      240

uggccauuga cuucggcacc acgucuagug gcuaugcuuu cagcuuugcc agugacccug      300

aggccaucca caugaugagg aaaugggagg gcggagaccc gggcguggcc caccagaaga      360

ccccgaccug ccugcugcug acuccggagg gcgccuucca cagcuuuggc uacaccgccc      420

gcgauuacua ccaugaccug gaccccgaag aggcgcggga cuggcucuac uucgagaagu      480

ucaagaugaa gauccacagc gccacggauc ucaccuugaa gacccagcua gaggcaguaa      540

auggaaagac gaugcccgcc cuggaggugu ucgcccaugc ccugcgcuuc uucagggagc      600

acgcccuuca ggagcugagg gagcagagcc caucgcugcc agagaaggac acugugcgcu      660

ggguguugac ggugccugcc aucuggaaac agccagccaa gcaguucaug cgggaggcug      720

ccuaccuggc uggacuugug ucccgagaga augcagagca gcuacucauc gcccuggagc      780

ccgaggccgc cucgguauac ugccgcaagc ugcgccugca ccagcuccug gaccugagug      840

gccgggcccc aggugguggg cgccugggug agcgccgcuc caucgacucc agcuuccguc      900

aggcucggga gcagcugcga aggucccgcc acagccgcac guuccuggug gagucaggcg      960

uaggagagcu gugggcagag augcaagcag gagaccgcua cgugguggcc gacugcggcg     1020

gaggcaccgu ggaccugacg gugcaccagc uggagcagcc ccauggcacc cucaaggagc     1080

ucuacaaggc aucugggggc ccuuauggcg cggugggcgu ggaccuggcc uucgagcagc     1140

ugcugugccg caucuucggc gaggacuuca ucgccaccuu caaaaggcaa cggccggcag     1200

ccuggguaga ucugaccauc gccuucgagg cucgcaagcg cacugcuggc ccacaccgug     1260

caggggcgcu caacaucucg cugcccuucu ccuucauuga cuucuaccgc aagcagcggg     1320

gccacaacgu ggagaccgcu cugcgcagga gcagcgugaa cuucgugaag ugguccucac     1380

aggggaugcu ccgaaugucu ugugaagcca ugaacgagcu cuuucagccc accgucagcg     1440

ggaucaucca gcacauagag gcccugcugg cacggccgga ggugcagggu gugaagcugc     1500

uguuccuagu gggcggcuuc gccgagucag cggugcugca gcacgcggug caggcggcgc     1560

ugggcgcccg cggucugcgu gucguggucc cgcacgacgu gggccucacc auccucaaag     1620

gcgcggugcu guucggccag gcgccgggcg uggugcgggu ccgccgcucg ccgcucaccu     1680

auggcguggg cgugcucaac cgcuuugugc cugggcgcca cccgcccgaa aagcugcugg     1740

uucgcgacgg ccgccgcugg ugcaccgacg ucuucgagcg cuucguggcc gccgagcagu     1800

cgguggcccu gggcgaggag gugcggcgca gcuacugccc ggcgcguccc ggccagcggc     1860

gcguacucau caaccuguac ugcugcgcgg cagaggaugc gcgcuucauc accgaccccg     1920

gcgugcgcaa augcggcgcg cucagccucg agcuugagcc cgccgacugc ggccaggaca     1980

ccgccggcgc gccucccggc cgccgcgaga uccgcgccgc caugcaguuu ggcgacaccg     2040

aaauuaaggu caccgccguc gacgucagca ccaaucgcuc cgugcgcgcg uccaucgacu     2100

uucuuuccaa cugaggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2160

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2220

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2280

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     2400

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       2443


<210>  6089
<211>  1912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (wt)

<400>  6089
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcgg       60

ccaucggagu ucaccugggc ugcaccucag ccuguguggc cgucuauaag gauggccggg      120

cugguguggu ugcaaaugau gccggugacc gaguuacucc agcuguuguu gcuuacucag      180

aaaaugaaga gauuguugga uuggcagcaa aacaaaguag aauaagaaau auuucaaaua      240

caguaaugaa aguaaagcag auccugggca gaagcuccag ugauccacaa gcucagaaau      300

acaucgcgga aaguaaaugu uuagucauug aaaaaaaugg gaaauuacga uaugaaauag      360

auacuggaga agaaacaaaa uuuguuaacc cagaagaugu ugccagacug auauuuagua      420

aaaugaaaga aacggcacau ucuguauugg gcucagaugc aaaugaugua guuauuacug      480

ucccguuuga uuuuggagaa aagcaaaaaa augcucuugg agaagcagcu agagcugcug      540

gauuuaaugu uuugcgauua auucacgaac cgucugcagc ucugcuugcu uauggaauug      600

gacaagacuc cccuacugga aaaagcaaua uuuugguguu uaagcuggga ggaacauccu      660

uaucucucag cgucauggaa guuaacagug gaauauaucg gguucuuuca acaaacacug      720

augauaacau cgguggugca cauuucacag aaaccuuagc acaguaucua gcuucugagu      780

uccaaagauc cuucaaacau gaugugagag gaaaugcgcg agccaugaug aaauuaacga      840

acagugcuga aguagcgaaa cauucuuugu caaccuuggg aagugccaac uguuuucuug      900

acucauuaua ugaaggucaa gauuuugauu gcaauguguc cagagcaaga uuugaacuuc      960

uuuguucucc acuuuuuaau aaguguauag aagcaaucag aggacucuua gaucaaaaug     1020

gauuuacagc agaugauauc aacaagguug uccuuugugg agggucuucu cgaaucccaa     1080

agcuacagca acugauuaaa gaucuuuucc cagcuguuga gcuucucaau ucuaucccuc     1140

cugaugaagu gaucccuauu ggugcagcua uagaagcagg aauccuuauu gggaaagaaa     1200

accuguuggu ggaagacucu cuuaugauag aguguucagc cagagauauu uuaguuaagg     1260

guguggacga aucaggagcc aguagauuca cagugcuguu uccaucaggg acuccuuugc     1320

cagcucgaag acaacacaca uugcaagccc cuggaagcau aucuucagug ugccuugaac     1380

ucuaugaguc ugaugggaag aacucugcca aagaggaaac caaguuugca cagguuguac     1440

uccaggauuu agauaaaaaa gaaaauggau uacgugauau auuagcuguu cuuacuauga     1500

aaagggaugg aucuuuacau gugacaugca cagaucaaga aacuggaaaa ugugaagcaa     1560

ucucuauuga gauagcaucu uagggacuag ugcaucacau uuaaaagcau cucagccuac     1620

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1680

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1740

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1800

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc     1860

cccccccccc cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu             1912


<210>  6090
<211>  2959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (wt)

<400>  6090
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugucgg       60

uggugggguu ggacgugggc ucgcagagcu gcuacaucgc gguagcccgg gccgggggca      120

ucgagaccau cgccaaugag uucagcgacc ggugcacccc gucagucaua ucauuuggau      180

caaaaaauag aacaaucgga guugcagcca aaaaucagca aaucacucau gcaaacaaua      240

cggugucuaa cuucaaaaga uuucauggcc gagcauucaa ugaccccuuc auucaaaagg      300

agaaggaaaa cuugaguuac gauuugguuc cauugaaaaa ugguggaguu ggaauaaagg      360

uaauguacau gggugaagaa caucuauuua guguggagca gauaacagcc auguuguuga      420

cuaagcugaa ggaaacugcu gaaaacagcc ucaagaaacc aguaacagau uguguuauuu      480

caguccccuc cuucuuuaca gaugcugaga ggcgaucugu guuagaugcu gcacagauug      540

uuggccuaaa cuguuuaaga cuuaugaaug acaugacagc uguugcuuug aauuacggaa      600

uuuauaagca ggaucuccca agccuggaug agaaaccucg gauagugguu uuuguugaua      660

ugggacauuc agcuuuucaa gugucugcuu gugcuuuuaa caagggaaaa uugaagguac      720

ugggaacagc uuuugauccu uucuuaggag gaaaaaacuu cgaugaaaag uuaguggaac      780

auuuuugugc agaauuuaaa acuaaguaca aguuggaugc aaaauccaaa auacgagcac      840

uccuacgucu guaucaggaa ugugaaaaac ugaaaaagcu aaugagcucu aacagcacag      900

accuuccacu gaauaucgaa ugcuuuauga augauaaaga uguuuccgga aagaugaaca      960

ggucacaauu ugaagaacuc ugugcugaac uucugcaaaa gauagaagua ccccuuuauu     1020

cacuguugga acaaacucau cucaaaguag aagaugugag ugcaguugag auuguuggag     1080

gcgcuacacg aaucccagcu gugaaggaaa gaauugccaa auucuuugga aaagauauua     1140

gcacaacacu caaugcagau gaagcaguag ccagaggaug ugcauuacag ugugcaauac     1200

uuuccccggc auuuaaaguu agagaauuuu ccgucacaga ugcaguuccu uuuccaauau     1260

cucugaucug gaaccaugau ucagaagaua cugaaggugu ucaugaaguc uuuagucgaa     1320

accaugcugc uccuuucucc aaaguucuca ccuuucugag aagggggccu uuugagcuag     1380

aagcauucua uucugauccc caaggaguuc cauauccaga agcaaaaaua ggccgcuuug     1440

uaguucagaa uguuucugca cagaaagaug gagaaaaauc uagaguaaaa gucaaagugc     1500

gagucaacac ccauggcauu uucaccaucu cuacggcauc uaugguggag aaagucccaa     1560

cugaggagaa ugaaaugucu ucugaagcug acauggagug ucugaaucag agaccaccag     1620

aaaacccaga cacugauaaa aauguccagc aagacaacag ugaagcugga acacagcccc     1680

agguacaaac ugaugcucaa caaaccucac agucuccccc uucaccugaa cuuaccucag     1740

aagaaaacaa aaucccagau gcugacaaag caaaugaaaa aaaaguugac cagccuccag     1800

aagcuaaaaa gcccaaaaua aaggugguga auguugagcu gccuauugaa gccaacuugg     1860

ucuggcaguu agggaaagac cuucuuaaca uguauauuga gacagagggu aagaugauaa     1920

ugcaagauaa auuggaaaaa gaaaggaaug augcuaaaaa ugcaguugag gaauaugugu     1980

augaguucag agacaagcug uguggaccau augaaaaauu uauaugugag caggaucauc     2040

aaaauuuuuu gagacuccuc acagaaacug aagacuggcu guaugaagaa ggagaggacc     2100

aagcuaaaca agcauauguu gacaaguugg aagaauuaau gaaaauuggc acuccaguua     2160

aaguucgguu ucaggaagcu gaagaacggc caaaaauguu ugaagaacua ggacagaggc     2220

ugcagcauua ugccaagaua gcagcugacu ucagaaauaa ggaugagaaa uacaaccaua     2280

uugaugaguc ugaaaugaaa aaaguggaga agucuguuaa ugaagugaug gaauggauga     2340

auaaugucau gaaugcucag gcuaaaaaga gucuugauca ggauccaguu guacgugcuc     2400

aggaaauuaa aacaaaaauc aaggaauuga acaacacaug ugaacccguu guaacacaac     2460

cgaaaccaaa aauugaauca cccaaacugg aaagaacucc aaauggccca aauauugaua     2520

aaaaggaaga agauuuagaa gacaaaaaca auuuuggugc ugaaccucca caucagaaug     2580

gugaauguua cccuaaugag aaaaauucug uuaauaugga cuuggacuag ggacuagugc     2640

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     2700

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     2760

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     2820

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu     2940

uuucagagcc accagaauu                                                  2959


<210>  6091
<211>  3382
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (wt)

<400>  6091
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcag       60

acaaaguuag gaggcagagg ccgaggaggc gagucuguug ggccuuggug gcugugcucu      120

uggcagaccu guuggcacug agugauacac uggcagugau gucuguggac cugggcagug      180

aguccaugaa gguggccauu gucaaaccug gagugcccau ggaaauuguc uugaauaagg      240

aaucucggag gaaaacaccg gugaucguga cccugaaaga aaaugaaaga uucuuuggag      300

acagugcagc aagcauggcg auuaagaauc caaaggcuac gcuacguuac uuccagcacc      360

uccuggggaa gcaggcagau aacccccaug uagcucuuua ccaggcccgc uucccggagc      420

acgagcugac uuucgaccca cagaggcaga cugugcacuu ucagaucagc ucgcagcugc      480

aguucucacc ugaggaagug uugggcaugg uucucaauua uucucguucu cuagcugaag      540

auuuugcaga gcagcccauc aaggaugcag ugaucaccgu gccagucuuc uucaaccagg      600

ccgagcgccg agcugugcug caggcugcuc guauggcugg ccucaaagug cugcagcuca      660

ucaaugacaa caccgccacu gcccucagcu auggugucuu ccgccggaaa gauauuaaca      720

ccacugccca gaauaucaug uucuaugaca ugggcucagg cagcaccgua ugcaccauug      780

ugaccuacca gauggugaag acuaaggaag cugggaugca gccacagcug cagauccggg      840

gaguaggauu ugaccguacc cuggggggcc uggagaugga gcuccggcuu cgagaacgcc      900

uggcugggcu uuucaaugag cagcgcaagg gucagagagc aaaggaugug cgggagaacc      960

cgcgugccau ggccaagcug cugcgugagg cuaaucggcu caaaaccguc cucagugcca     1020

acgcugacca cauggcacag auugaaggcc ugauggauga uguggacuuc aaggcaaaag     1080

ugacucgugu ggaauuugag gaguugugug cagacuuguu ugagcgggug ccugggccug     1140

uacagcaggc ccuccagagu gccgaaauga gucuggauga gauugagcag gucauccugg     1200

uggguggggc cacucggguc cccagaguuc aggaggugcu gcugaaggcc gugggcaagg     1260

aggagcuggg gaagaacauc aaugcagaug aagcagccgc caugggggca guguaccagg     1320

cagcugcgcu cagcaaagcc uuuaaaguga agccauuugu cguccgagau gcaguggucu     1380

accccauccu gguggaguuc acgagggagg uggaggagga gccugggauu cacagccuga     1440

agcacaauaa acggguacuc uucucucgga uggggcccua cccucaacgc aaagucauca     1500

ccuuuaaccg cuacagccau gauuucaacu uccacaucaa cuacggcgac cugggcuucc     1560

uggggccuga agaucuucgg guauuuggcu cccagaaucu gaccacagug aagcuaaaag     1620

ggguggguga cagcuucaag aaguauccug acuacgaguc caagggcauc aaggcucacu     1680

ucaaccugga ugagaguggc gugcucaguc uagacagggu ggagucugua uuugagacac     1740

ugguagagga cagcgcagaa gaggaaucua cucucaccaa acuuggcaac accauuucca     1800

gccuguuugg aggcgguacc acaccagaug ccaaggagaa ugguacugau acuguccagg     1860

aggaagagga gagcccugca gaggggagca aggacgagcc uggggagcag gucgagcuca     1920

aggaggaagc ugaggcccca guggaggaug gcucucagcc cccacccccu gaaccuaagg     1980

gagaugcaac cccugaggga gaaaaggcca cagaaaaaga aaauggggac aagucugagg     2040

cccagaaacc aagugagaag gcagaggcag ggccugaggg cgucgcucca gccccagagg     2100

gagagaagaa gcagaagccc gccaggaagc ggcgaauggu agaggagauc gggguggagc     2160

ugguuguucu ggaccugccu gacuugccag aggauaagcu ggcucagucg gugcagaaac     2220

uucaggacuu gacacuccga gaccuggaga agcaggaacg ggaaaaagcu gccaacagcu     2280

uggaagcauu cauauuugag acccaggaca agcuguacca gcccgaguac caggaagugu     2340

ccacagagga gcagcgugag gagaucucug ggaagcucag cgccgcaucc accuggcugg     2400

aggaugaggg uguuggagcc accacaguga uguugaagga gaagcuggcu gagcugagga     2460

agcugugcca agggcuguuu uuucggguag aggagcgcaa gaaguggccc gaacggcugu     2520

cugcccucga uaaucuccuc aaccauucca gcauguuccu caagggggcc cggcucaucc     2580

cagagaugga ccagaucuuc acugaggugg agaugacaac guuagagaaa gucaucaaug     2640

agaccugggc cuggaagaau gcaacucugg ccgagcaggc uaagcugccc gccacagaga     2700

agccuguguu gcucucaaaa gacauugaag cuaagaugau ggcccuggac cgagaggugc     2760

aguaucugcu caauaaggcc aaguuuacca agccccggcc ccggccuaag gacaagaaug     2820

ggacccgggc agagccaccc cucaaugcca gugccaguga ccagggggag aaggucaucc     2880

cuccagcagg ccagacugaa gaugcagagc ccauuucaga accugagaaa guagagacug     2940

gauccgagcc aggagacacu gagccuuugg aguuaggagg uccuggagca gaaccugaac     3000

agaaagaaca aucgacagga cagaagcggc cuuugaagaa cgacgaacua uaaggacuag     3060

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     3120

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     3180

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     3240

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     3360

ucuuuucaga gccaccagaa uu                                              3382


<210>  6092
<211>  2581
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (wt)

<400>  6092
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccug       60

aggaaaccca gacccaagac caaccgaugg aggaggagga gguugagacg uucgccuuuc      120

aggcagaaau ugcccaguug augucauuga ucaucaauac uuucuacucg aacaaagaga      180

ucuuucugag agagcucauu ucaaauucau cagaugcauu ggacaaaauc cgguaugaga      240

gcuugacaga ucccaguaaa uuagacucug ggaaagagcu gcauauuaac cuuauaccga      300

acaaacaaga ucgaacucuc acuauugugg auacuggaau uggaaugacc aaggcugacu      360

ugaucaauaa ccuugguacu aucgccaagu cugggaccaa agcguucaug gaagcauugc      420

aggcuggugc agauaucucu augauuggcc aguucggugu ugguuuuuau ucugcuuauu      480

ugguugcuga gaaaguaacu gugaucacca aacauaacga ugaugagcag uacgcuuggg      540

aguccucagc agggggauca uucacaguga ggacagacac aggugaaccu augggucgug      600

gaacaaaagu uauccuacac cugaaagaag accaaacuga guacuuggag gaacgaagaa      660

uaaaggagau ugugaagaaa cauucucagu uuauuggaua ucccauuacu cuuuuugugg      720

agaaggaacg ugauaaagaa guaagcgaug augaggcuga agaaaaggaa gacaaagaag      780

aagaaaaaga aaaagaagag aaagagucgg aagacaaacc ugaaauugaa gauguugguu      840

cugaugagga agaagaaaag aaggauggug acaagaagaa gaagaagaag auuaaggaaa      900

aguacaucga ucaagaagaa cucaacaaaa caaagcccau cuggaccaga aaucccgacg      960

auauuacuaa ugaggaguac ggagaguucu auaagagcuu gaccaaugac ugggaagauc     1020

acuuggcagu gaagcauuuu ucaguugaag gacaguugga guucagagcc cuucuauuug     1080

ucccacgacg ugcuccuuuu gaucuguuug aaaacagaaa gaaaaagaac aacaucaaau     1140

uguauguacg cagaguuuuc aucauggaua acugugagga gcuaaucccu gaauaucuga     1200

acuucauuag agggguggua gacucggagg aucucccucu aaacauaucc cgugagaugu     1260

ugcaacaaag caaaauuuug aaaguuauca ggaagaauuu ggucaaaaaa ugcuuagaac     1320

ucuuuacuga acuggcggaa gauaaagaga acuacaagaa auucuaugag caguucucua     1380

aaaacauaaa gcucggaaua cacgaagacu cucaaaaucg gaagaagcuc ucagagcugu     1440

uaagguacua cacaucugcc ucuggugaug agaugguuuc ucucaaggac uacugcacca     1500

gaaugaagga gaaccagaaa cauaucuauu auaucacagg ugagaccaag gaccagguag     1560

cuaacucagc cuuuguggaa cgucuucgga aacauggcuu agaagugauc uauaugauug     1620

agcccauuga ugaguacugu guccaacagc ugaaggaauu ugaggggaag acuuuagugu     1680

cagucaccaa agaaggccug gaacuuccag aggaugaaga agagaaaaag aagcaggaag     1740

agaaaaaaac aaaguuugag aaccucugca aaaucaugaa agacauauug gagaaaaaag     1800

uugaaaaggu gguuguguca aaccgauugg ugacaucucc augcuguauu gucacaagca     1860

cauauggcug gacagcaaac auggagagaa ucaugaaagc ucaagcccua agagacaacu     1920

caacaauggg uuacauggca gcaaagaaac accuggagau aaacccugac cauuccauua     1980

uugagaccuu aaggcaaaag gcagaggcug auaagaacga caagucugug aaggaucugg     2040

ucaucuugcu uuaugaaacu gcgcuccugu cuucuggcuu cagucuggaa gauccccaga     2100

cacaugcuaa caggaucuac aggaugauca aacuuggucu ggguauugau gaagaugacc     2160

cuacugcuga ugauaccagu gcugcuguaa cugaagaaau gccaccccuu gaaggagaug     2220

acgacacauc acgcauggaa gaaguagacu aaggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     2520

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     2580

u                                                                     2581


<210>  6093
<211>  721
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (wt)

<400>  6093
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggauu       60

ccaguaaauu agacucuggg aaagggcugc auauuaaccu uguaccaaac aaacaaaauc      120

aaacccucac uauuguggac acuagaauug gaaugaccaa gacugacuug aucaauaacc      180

ucgguacugu caccaagucu gggaccaaag cauucaugga agcauugcag gcugaugcag      240

auaucucuau gauuggccau uucgggguug guuuuuauuc ugcuuauuug guugccaaga      300

aaguaacugu gaucagcaaa cauaacaaug augagcagua caccugggag uccucagcag      360

ggggaucauu cacagugagg acagacgagu gaggacuagu gcaucacauu uaaaagcauc      420

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      480

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      540

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      660

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau      720

u                                                                      721


<210>  6094
<211>  2557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (wt)

<400>  6094
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccug       60

aggaagugca ccauggagag gaggaggugg agacuuuugc cuuucaggca gaaauugccc      120

aacucauguc ccucaucauc aauaccuucu auuccaacaa ggagauuuuc cuucgggagu      180

ugaucucuaa ugcuucugau gccuuggaca agauucgcua ugagagccug acagacccuu      240

cgaaguugga cagugguaaa gagcugaaaa uugacaucau ccccaacccu caggaacgua      300

cccugacuuu gguagacaca ggcauuggca ugaccaaagc ugaucucaua aauaauuugg      360

gaaccauugc caagucuggu acuaaagcau ucauggaggc ucugcaggcu ggugcagaca      420

ucuccaugau ugggcaguuu gguguuggcu uuuauucugc cuacuuggug gcagagaaag      480

ugguugugau cacaaagcac aacgaugaug aacaguaugc uugggagucu ucugcuggag      540

guuccuucac ugugcgugcu gaccauggug agcccauugg cagggguacc aaagugaucc      600

uccaucuuaa agaagaucag acagaguacc uagaagagag gcgggucaaa gaaguaguga      660

agaagcauuc ucaguucaua ggcuauccca ucacccuuua uuuggagaag gaacgagaga      720

aggaaauuag ugaugaugag gcagaggaag agaaagguga gaaagaagag gaagauaaag      780

augaugaaga aaaacccaag aucgaagaug uggguucaga ugaggaggau gacagcggua      840

aggauaagaa gaagaaaacu aagaagauca aagagaaaua cauugaucag gaagaacuaa      900

acaagaccaa gccuauuugg accagaaacc cugaugacau cacccaagag gaguauggag      960

aguucuacaa gagccucacu aaugacuggg aagaccacuu ggcagucaag cacuuuucug     1020

uagaagguca guuggaguuc agggcauugc uauuuauucc ucgucgggcu cccuuugacc     1080

uuuuugagaa caagaagaaa aagaacaaca ucaaacucua uguccgccgu guguucauca     1140

uggacagcug ugaugaguug auaccagagu aucucaauuu uauccguggu gugguugacu     1200

cugaggaucu gccccugaac aucucccgag aaaugcucca gcagagcaaa aucuugaaag     1260

ucauucgcaa aaacauuguu aagaagugcc uugagcuguu cucugagcug gcagaagaca     1320

aggagaauua caagaaauuc uaugaggcau ucucuaaaaa ucucaagcuc ggaauccacg     1380

aagacuccac uaaccgccgc cgccugucug agcugcugcg cuaucauacc ucccagucug     1440

gagaugagau gacaucucug ucagaguaug uuucucgcau gaaggagaca cagaagucca     1500

ucuauuacau cacuggugag agcaaagagc aggucgccaa cucagcuuuu guggagcgag     1560

ugcggaaacg gggcuucgag gugguauaua ugaccgagcc cauugacgag uacugugugc     1620

agcagcucaa ggaauuugau gggaaaagcc uggucucagu uaccaaggag ggucuggagc     1680

ugccugagga ugaggaggag aagaagaaga uggaagagag caaggcaaag uuugagaacc     1740

ucugcaagcu caugaaagaa aucuuagaua agaagguuga gaaggugaca aucuccaaua     1800

gacuuguguc uucaccuugc ugcauuguga ccagcaccua cggcuggaca gccaauaugg     1860

agcggaucau gaaagcccag gcacuucggg acaacuccac caugggcuau augauggcca     1920

aaaagcaccu ggagaucaac ccugaccacc ccauugugga gacgcugcgg cagaaggcug     1980

aggccgacaa gaaugauaag gcaguuaagg accugguggu gcugcuguuu gaaaccgccc     2040

ugcuaucuuc uggcuuuucc cuugaggauc cccagaccca cuccaaccgc aucuaucgca     2100

ugaucaagcu aggucuaggu auugaugaag augaaguggc agcagaggaa cccaaugcug     2160

caguuccuga ugagaucccc ccucucgagg gcgaugagga ugcgucucgc auggaagaag     2220

ucgauuaggg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2280

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2340

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2400

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2520

ccccccccca aaggcucuuu ucagagccac cagaauu                              2557


<210>  6095
<211>  2794
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (wt)

<400>  6095
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaggg       60

cccugugggu gcugggccuc ugcugcgucc ugcugaccuu cgggucgguc agagcugacg      120

augaaguuga uguggauggu acaguagaag aggaucuggg uaaaaguaga gaaggaucaa      180

ggacggauga ugaaguagua cagagagagg aagaagcuau ucaguuggau ggauuaaaug      240

caucacaaau aagagaacuu agagagaagu cggaaaaguu ugccuuccaa gccgaaguua      300

acagaaugau gaaacuuauc aucaauucau uguauaaaaa uaaagagauu uuccugagag      360

aacugauuuc aaaugcuucu gaugcuuuag auaagauaag gcuaauauca cugacugaug      420

aaaaugcucu uucuggaaau gaggaacuaa cagucaaaau uaagugugau aaggagaaga      480

accugcugca ugucacagac accgguguag gaaugaccag agaagaguug guuaaaaacc      540

uugguaccau agccaaaucu gggacaagcg aguuuuuaaa caaaaugacu gaagcacagg      600

aagauggcca gucaacuucu gaauugauug gccaguuugg ugucgguuuc uauuccgccu      660

uccuuguagc agauaagguu auugucacuu caaaacacaa caacgauacc cagcacaucu      720

gggagucuga cuccaaugaa uuuucuguaa uugcugaccc aagaggaaac acucuaggac      780

ggggaacgac aauuacccuu gucuuaaaag aagaagcauc ugauuaccuu gaauuggaua      840

caauuaaaaa ucucgucaaa aaauauucac aguucauaaa cuuuccuauu uauguaugga      900

gcagcaagac ugaaacuguu gaggagccca uggaggaaga agaagcagcc aaagaagaga      960

aagaagaauc ugaugaugaa gcugcaguag aggaagaaga agaagaaaag aaaccaaaga     1020

cuaaaaaagu ugaaaaaacu gucugggacu gggaacuuau gaaugauauc aaaccaauau     1080

ggcagagacc aucaaaagaa guagaagaag augaauacaa agcauucuac aaaucauuuu     1140

caaaggaaag ugaugacccc auggcuuaua uucacuuuac ugcugaaggg gaaguuaccu     1200

ucaaaucaau uuuauuugua cccacaucug cuccacgugg ucuguuugac gaauauggau     1260

cuaaaaagag cgauuacauu aagcucuaug ugcgccgugu auucaucaca gacgacuucc     1320

augauaugau gccuaaauac cucaauuuug ucaagggugu gguggacuca gaugaucucc     1380

ccuugaaugu uucccgcgag acucuucagc aacauaaacu gcuuaaggug auuaggaaga     1440

agcugguucg uaaaacgcug gacaugauca agaagauugc ugaugauaaa uacaaugaua     1500

cuuuuuggaa agaauuuggu accaacauca agcugggugu gauugaagac cacucgaauc     1560

gaacacgucu ugcuaaacuu cuuagguucc agucuucuca ucauccaacu gacauuacua     1620

gccuagacca guauguggaa agaaugaagg aaaaacaaga caaaaucuac uucauggcug     1680

gguccagcag aaaagaggcu gaaucuucuc cauuuguuga gcgacuucug aaaaagggcu     1740

augaaguuau uuaccucaca gaaccugugg augaauacug uauucaggcc cuucccgaau     1800

uugaugggaa gagguuccag aauguugcca aggaaggagu gaaguucgau gaaagugaga     1860

aaacuaagga gagucgugaa gcaguugaga aagaauuuga gccucugcug aauuggauga     1920

aagauaaagc ccuuaaggac aagauugaaa aggcuguggu gucucagcgc cugacagaau     1980

cuccgugugc uuugguggcc agccaguacg gauggucugg caacauggag agaaucauga     2040

aagcacaagc guaccaaacg ggcaaggaca ucucuacaaa uuacuaugcg agucagaaga     2100

aaacauuuga aauuaauccc agacacccgc ugaucagaga caugcuucga cgaauuaagg     2160

aagaugaaga ugauaaaaca guuuuggauc uugcuguggu uuuguuugaa acagcaacgc     2220

uucggucagg guaucuuuua ccagacacua aagcauaugg agauagaaua gaaagaaugc     2280

uucgccucag uuugaacauu gacccugaug caaaggugga agaagaaccc gaagaagaac     2340

cugaagagac agcagaagac acaacagaag acacagagca agacgaagau gaagaaaugg     2400

augugggaac agaugaagaa gaagaaacag caaaggaauc uacagcugaa aaagaugaau     2460

uguaaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     2520

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     2580

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     2640

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc     2760

ccccccaaag gcucuuuuca gagccaccag aauu                                 2794


<210>  6096
<211>  2497
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (wt)

<400>  6096
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcgc       60

gcgagcugcg ggcgcugcug cuguggggcc gccgccugcg gccuuugcug cgggcgccgg      120

cgcuggcggc cgugccggga ggaaaaccaa uucugugucc ucggaggacc acagcccagu      180

ugggccccag gcgaaaccca gccuggagcu ugcaggcagg acgacuguuc agcacgcaga      240

ccgccgagga caaggaggaa ccccugcacu cgauuaucag cagcacagag agcgugcagg      300

guuccacuuc caaacaugag uuccaggccg agacaaagaa gcuguuggac auuguugccc      360

ggucccugua cucagaaaaa gagguguuua uacgggagcu gaucuccaau gccagcgaug      420

ccuuggaaaa acugcgucac aaacuggugu cugacggcca agcacugcca gaaauggaga      480

uucacuugca gaccaaugcc gagaaaggca ccaucaccau ccaggauacu gguaucggga      540

ugacacagga agaacuggug uccaaccugg ggacgauugc cagaucgggg ucaaaggccu      600

uccuggaugc ucugcagaac caggcugagg ccagcagcaa gaucaucggc caguuuggag      660

uggguuucua cucagcuuuc augguggcug acagagugga ggucuauucc cgcucggcag      720

ccccggggag ccuggguuac caguggcuuu cagaugguuc uggaguguuu gaaaucgccg      780

aagcaucggg aguuagaacc gggacaaaaa ucaucaucca ccugaaaucc gacugcaagg      840

aguuuuccag cgaggcccgg gugcgagaug ugguaacgaa guacagcaac uucgucagcu      900

uccccuugua cuugaaugga aggcggauga acaccuugca ggccaucugg augauggacc      960

ccaaggaugu ccgugagugg caacaugagg aguucuaccg cuacgucgcg caggcucacg     1020

acaagccccg cuacacccug cacuauaaga cggacgcacc gcucaacauc cgcagcaucu     1080

ucuacgugcc cgacaugaaa ccguccaugu uugaugugag ccgggagcug ggcuccagcg     1140

uugcacugua cagccgcaaa guccucaucc agaccaaggc cacggacauc cugcccaagu     1200

ggcugcgcuu cauccgaggu gugguggaca gugaggacau uccccugaac cucagccggg     1260

agcugcugca ggagagcgca cucaucagga aacuccggga cguuuuacag cagaggcuga     1320

ucaaauucuu cauugaccag aguaaaaaag augcugagaa guaugcaaag uuuuuugaag     1380

auuacggccu guucaugcgg gagggcauug ugaccgccac cgagcaggag gucaaggagg     1440

acauagcaaa gcugcugcgc uacgaguccu cggcgcugcc cuccgggcag cuaaccagcc     1500

ucucagaaua cgccagccgc augcgggccg gcacccgcaa caucuacuac cugugcgccc     1560

ccaaccguca ccuggcagag cacucacccu acuaugaggc caugaagaag aaagacacag     1620

agguucucuu cugcuuugag caguuugaug agcucacccu gcugcaccuu cgugaguuug     1680

acaagaagaa gcugaucucu guggagacgg acauagucgu ggaucacuac aaggaggaga     1740

aguuugagga caggucccca gccgccgagu gccuaucaga gaaggagacg gaggagcuca     1800

uggccuggau gagaaaugug cuggggucgc gugucaccaa cgugaaggug acccuccgac     1860

uggacaccca cccugccaug gucaccgugc uggagauggg ggcugcccgc cacuuccugc     1920

gcaugcagca gcuggccaag acccaggagg agcgcgcaca gcuccugcag cccacgcugg     1980

agaucaaccc caggcacgcg cucaucaaga agcugaauca gcugcgcgca agcgagccug     2040

gccuggcuca gcugcuggug gaucagauau acgagaacgc caugauugcu gcuggacuug     2100

uugacgaccc uagggccaug gugggccgcu ugaaugagcu gcuugucaag gcccuggagc     2160

gacacugagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     2220

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     2280

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     2340

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     2460

ccccccccca aaggcucuuu ucagagccac cagaauu                              2497


<210>  6097
<211>  844
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (wt)

<400>  6097
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugggaa       60

aaaucagcag ucuuccaacc caauuauuua agugcugcuu uugugauuuc uugaagguga      120

agaugcacac cauguccucc ucgcaucucu ucuaccuggc gcugugccug cucaccuuca      180

ccagcucugc cacggcugga ccggagacgc ucugcggggc ugagcuggug gaugcucugc      240

aguucgugug uggagacagg ggcuuuuauu ucaacaagcc cacaggguau ggcuccagca      300

gucggagggc gccucagaca ggcaucgugg augagugcug cuuccggagc ugugaucuaa      360

ggaggcugga gauguauugc gcaccccuca agccugccaa gucagcucgc ucuguccgug      420

cccagcgcca caccgacaug cccaagaccc agaaggaagu acauuugaag aacgcaagua      480

gagggagugc aggaaacaag aacuacagga uguagggacu agugcaucac auuuaaaagc      540

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      600

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      660

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

ugcauccccc cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag      840

aauu                                                                   844


<210>  6098
<211>  1021
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (wt)

<400>  6098
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaacu       60

ccuucuccac aagcgccuuc gguccaguug ccuucucccu ggggcugcuc cugguguugc      120

cugcugccuu cccugcccca guacccccag gagaagauuc caaagaugua gccgccccac      180

acagacagcc acucaccucu ucagaacgaa uugacaaaca aauucgguac auccucgacg      240

gcaucucagc ccugagaaag gagacaugua acaagaguaa caugugugaa agcagcaaag      300

aggcacuggc agaaaacaac cugaaccuuc caaagauggc ugaaaaagau ggaugcuucc      360

aaucuggauu caaugaggag acuugccugg ugaaaaucau cacuggucuu uuggaguuug      420

agguauaccu agaguaccuc cagaacagau uugagaguag ugaggaacaa gccagagcug      480

ugcagaugag uacaaaaguc cugauccagu uccugcagaa aaaggcaaag aaucuagaug      540

caauaaccac cccugaccca accacaaaug ccagccugcu gacgaagcug caggcacaga      600

accaguggcu gcaggacaug acaacucauc ucauucugcg cagcuuuaag gaguuccugc      660

aguccagccu gagggcucug cggcaaaugu agggacuagu gcaucacauu uaaaagcauc      720

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu      780

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu      840

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc      960

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1020

u                                                                     1021


<210>  6099
<211>  1663
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (wt)

<400>  6099
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcccu       60

ugcuuuggcu gagaggauuu cuguuggcaa guugcuggau uauagugagg aguuccccca      120

ccccaggauc cgaggggcac agcgcggccc ccgacugucc guccugugcg cuggccgccc      180

ucccaaagga uguacccaac ucucagccag agauggugga ggccgucaag aagcacauuu      240

uaaacaugcu gcacuugaag aagagacccg augucaccca gccgguaccc aaggcggcgc      300

uucugaacgc gaucagaaag cugcaugugg gcaaagucgg ggagaacggg uauguggaga      360

uagaggauga cauuggaagg agggcagaaa ugaaugaacu uauggagcag accucggaga      420

ucaucacguu ugccgaguca ggaacagcca ggaagacgcu gcacuucgag auuuccaagg      480

aaggcaguga ccugucagug guggagcgug cagaagucug gcuguuccua aaagucccca      540

aggccaacag gaccaggacc aaagucacca uccgccucuu ccagcagcag aagcacccgc      600

agggcagcuu ggacacaggg gaagaggccg aggaaguggg cuuaaagggg gagaggagug      660

aacuguugcu cucugaaaaa guaguagacg cucggaaaag caccuggcau gucuucccug      720

ucuccagcag cauccagcgg uugcuggacc agggcaagag cucccuggac guucggauug      780

ccugugagca gugccaggag aguggcgcca gcuugguucu ccugggcaag aagaagaaga      840

aagaagagga gggggaaggg aaaaagaagg gcggagguga agguggggca ggagcagaug      900

aggaaaagga gcagucgcac agaccuuucc ucaugcugca ggcccggcag ucugaagacc      960

acccucaucg ccggcgucgg cggggcuugg agugugaugg caaggucaac aucugcugua     1020

agaaacaguu cuuugucagu uucaaggaca ucggcuggaa ugacuggauc auugcucccu     1080

cuggcuauca ugccaacuac ugcgagggug agugcccgag ccauauagca ggcacguccg     1140

gguccucacu guccuuccac ucaacaguca ucaaccacua ccgcaugcgg ggccauagcc     1200

ccuuugccaa ccucaaaucg ugcugugugc ccaccaagcu gagacccaug uccauguugu     1260

acuaugauga uggucaaaac aucaucaaaa aggacauuca gaacaugauc guggaggagu     1320

gugggugcuc auagggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     1380

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     1440

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     1500

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc     1620

cccccccccc cccccaaagg cucuuuucag agccaccaga auu                       1663


<210>  6100
<211>  3841
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (wt)

<400>  6100
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcuc       60

ucagaguccu ucuguuaaca gccuugaccu uaugucaugg guucaacuug gacacugaaa      120

acgcaaugac cuuccaagag aacgcaaggg gcuucgggca gagcgugguc cagcuucagg      180

gauccagggu ggugguugga gccccccagg agauaguggc ugccaaccaa aggggcagcc      240

ucuaccagug cgacuacagc acaggcucau gcgagcccau ccgccugcag guccccgugg      300

aggccgugaa caugucccug ggccuguccc uggcagccac caccagcccc ccucagcugc      360

uggccugugg ucccaccgug caccagacuu gcagugagaa cacguaugug aaagggcucu      420

gcuuccuguu uggauccaac cuacggcagc agccccagaa guucccagag gcccuccgag      480

gguguccuca agaggauagu gacauugccu ucuugauuga uggcucuggu agcaucaucc      540

cacaugacuu ucggcggaug aaggaguuug ucucaacugu gauggagcaa uuaaaaaagu      600

ccaaaaccuu guucucuuug augcaguacu cugaagaguu ccggauucac uuuaccuuca      660

aagaguucca gaacaacccu aacccaagau cacuggugaa gccaauaacg cagcugcuug      720

ggcggacaca cacggccacg ggcauccgca aagugguacg agagcuguuu aacaucacca      780

acggagcccg aaagaaugcc uuuaagaucc uaguugucau cacggaugga gaaaaguuug      840

gcgaucccuu gggauaugag gaugucaucc cugaggcaga cagagaggga gucauucgcu      900

acgucauugg ggugggagau gccuuccgca gugagaaauc ccgccaagag cuuaauacca      960

ucgcauccaa gccgccucgu gaucacgugu uccaggugaa uaacuuugag gcucugaaga     1020

ccauucagaa ccagcuucgg gagaagaucu uugcgaucga ggguacucag acaggaagua     1080

gcagcuccuu ugagcaugag augucucagg aaggcuucag cgcugccauc accucuaaug     1140

gccccuugcu gagcacugug gggagcuaug acugggcugg uggagucuuu cuauauacau     1200

caaaggagaa aagcaccuuc aucaacauga ccagagugga uucagacaug aaugaugcuu     1260

acuuggguua ugcugccgcc aucaucuuac ggaaccgggu gcaaagccug guucuggggg     1320

caccucgaua ucagcacauc ggccugguag cgauguucag gcagaacacu ggcauguggg     1380

aguccaacgc uaaugucaag ggcacccaga ucggcgccua cuucggggcc ucccucugcu     1440

ccguggacgu ggacagcaac ggcagcaccg accugguccu caucggggcc ccccauuacu     1500

acgagcagac ccgagggggc cagguguccg ugugccccuu gcccaggggg agggcucggu     1560

ggcaguguga ugcuguucuc uacggggagc agggccaacc cuggggccgc uuuggggcag     1620

cccuaacagu gcugggggac guaaaugggg acaagcugac ggacguggcc auuggggccc     1680

caggagagga ggacaaccgg ggugcuguuu accuguuuca cggaaccuca ggaucuggca     1740

ucagccccuc ccauagccag cggauagcag gcuccaagcu cucucccagg cuccaguauu     1800

uuggucaguc acugaguggg ggccaggacc ucacaaugga uggacuggua gaccugacug     1860

uaggagccca ggggcacgug cugcugcuca ggucccagcc aguacugaga gucaaggcaa     1920

ucauggaguu caaucccagg gaaguggcaa ggaauguauu ugaguguaau gaucaggugg     1980

ugaaaggcaa ggaagccgga gaggucagag ucugccucca uguccagaaa agcacacggg     2040

aucggcuaag agaaggacag auccagagug uugugacuua ugaccuggcu cuggacuccg     2100

gccgcccaca uucccgcgcc gucuucaaug agacaaagaa cagcacacgc agacagacac     2160

aggucuuggg gcugacccag acuugugaga cccugaaacu acaguugccg aauugcaucg     2220

aggacccagu gagccccauu gugcugcgcc ugaacuucuc ucugguggga acgccauugu     2280

cugcuuucgg gaaccuccgg ccagugcugg cggaggaugc ucagagacuc uucacagccu     2340

uguuucccuu ugagaagaau uguggcaaug acaacaucug ccaggaugac cucagcauca     2400

ccuucaguuu caugagccug gacugccucg uggugggugg gccccgggag uucaacguga     2460

cagugacugu gagaaaugau ggugaggacu ccuacaggac acaggucacc uucuucuucc     2520

cgcuugaccu guccuaccgg aaggugucca cgcuccagaa ccagcgcuca cagcgauccu     2580

ggcgccuggc cugugagucu gccuccucca ccgaaguguc uggggccuug aaaagcacca     2640

gcugcagcau aaaccacccc aucuucccgg aaaacucaga ggucaccuuu aauaucacgu     2700

uugauguaga cucuaaggcu ucccuuggaa acaaacugcu ccucaaggcc aaugugacca     2760

gugagaacaa caugcccaga accaacaaaa ccgaguucca acuggagcug ccggugaaau     2820

augcugucua cauggugguc accagccaug gggucuccac uaaauaucuc aacuucacgg     2880

ccucagagaa uaccagucgg gucaugcagc aucaauauca ggucagcaac cuggggcaga     2940

ggagccuccc caucagccug guguucuugg ugcccguccg gcugaaccag acugucauau     3000

gggaccgccc ccaggucacc uucuccgaga accucucgag uacgugccac accaaggagc     3060

gcuugcccuc ucacuccgac uuucuggcug agcuucggaa ggcccccgug gugaacugcu     3120

ccaucgcugu cugccagaga auccagugug acaucccguu cuuuggcauc caggaagagu     3180

ucaaugcuac ccucaaaggc aaccucucgu uugacuggua caucaagacc ucgcauaacc     3240

accuccugau cgugagcaca gcugagaucu uguuuaacga uuccguguuc acccugcugc     3300

cgggacaggg ggcguuugug aggucccaga cggagaccaa aguggagccg uucgaggucc     3360

ccaacccccu gccgcucauc gugggcagcu cugucggggg acugcugcuc cuggcccuca     3420

ucaccgccgc gcuguacaag cucggcuucu ucaagcggca auacaaggac augaugagug     3480

aagggggucc cccgggggcc gaaccccagu agggacuagu gcaucacauu uaaaagcauc     3540

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     3600

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     3660

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     3720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     3780

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     3840

u                                                                     3841


<210>  6101
<211>  1786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (wt)

<400>  6101
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguucu       60

cccugaagac gcuuccauuu cugcucuuac uccaugugca gauuuccaag gccuuuccug      120

uaucuucuaa agagaaaaau acaaaaacug uucaggacua ccuggaaaag uucuaccaau      180

uaccaagcaa ccaguaucag ucuacaagga agaauggcac uaaugugauc guugaaaagc      240

ugaaagaaau gcagcgauuu uuuggguuga augugacggg gaagccaaau gaggaaacuc      300

uggacaugau gaaaaagccu cgcuguggag ugccugacag uggugguuuu auguuaaccc      360

caggaaaccc caagugggaa cgcacuaacu ugaccuacag gauucgaaac uauaccccac      420

agcugucaga ggcugaggua gaaagagcua ucaaggaugc cuuugaacuc uggaguguug      480

caucaccucu caucuucacc aggaucucac agggagaggc agauaucaac auugcuuuuu      540

accaaagaga ucacggugac aauucuccau uugauggacc caauggaauc cuugcucaug      600

ccuuucagcc aggccaaggu auuggaggag augcucauuu ugaugccgaa gaaacaugga      660

ccaacaccuc cgcaaauuac aacuuguuuc uuguugcugc ucaugaauuu ggccauucuu      720

uggggcucgc ucacuccucu gacccuggug ccuugaugua ucccaacuau gcuuucaggg      780

aaaccagcaa cuacucacuc ccucaagaug acaucgaugg cauucaggcc aucuauggac      840

uuucaagcaa cccuauccaa ccuacuggac caagcacacc caaacccugu gaccccaguu      900

ugacauuuga ugcuaucacc acacuccgug gagaaauacu uuucuuuaaa gacagguacu      960

ucuggagaag gcauccucag cuacaaagag ucgaaaugaa uuuuauuucu cuauucuggc     1020

caucccuucc aacugguaua caggcugcuu augaagauuu ugacagagac cucauuuucc     1080

uauuuaaagg caaccaauac ugggcucuga guggcuauga uauucugcaa gguuauccca     1140

aggauauauc aaacuauggc uuccccagca gcguccaagc aauugacgca gcuguuuucu     1200

acagaaguaa aacauacuuc uuuguaaaug accaauucug gagauaugau aaccaaagac     1260

aauucaugga gccagguuau cccaaaagca uaucaggugc cuuuccagga auagagagua     1320

aaguugaugc aguuuuccag caagaacauu ucuuccaugu cuucagugga ccaagauauu     1380

acgcauuuga ucuuauugcu cagagaguua ccagaguugc aagaggcaau aaauggcuua     1440

acuguagaua uggcugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     1500

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     1560

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     1620

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     1740

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    1786


<210>  6102
<211>  2506
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (wt)

<400>  6102
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugagcc       60

ucuggcagcc ccugguccug gugcuccugg ugcugggcug cugcuuugcu gcccccagac      120

agcgccaguc cacccuugug cuguucccug gagaccugag aaccaaucuc accgacaggc      180

agcuggcaga ggaauaccug uaccgcuaug guuacacucg gguggcagag augcguggag      240

agucgaaauc ucuggggccu gcgcugcugc uucuccagaa gcaacugucc cugcccgaga      300

ccggugagcu ggauagcgcc acgcugaagg ccaugcgaac cccacggugc ggggucccag      360

accugggcag auuccaaacc uuugagggcg accucaagug gcaccaccac aacaucaccu      420

auuggaucca aaacuacucg gaagacuugc cgcgggcggu gauugacgac gccuuugccc      480

gcgccuucgc acuguggagc gcggugacgc cgcucaccuu cacucgcgug uacagccggg      540

acgcagacau cgucauccag uuuggugucg cggagcacgg agacggguau cccuucgacg      600

ggaaggacgg gcuccuggca cacgccuuuc cuccuggccc cggcauucag ggagacgccc      660

auuucgacga ugacgaguug uggucccugg gcaagggcgu cgugguucca acucgguuug      720

gaaacgcaga uggcgcggcc ugccacuucc ccuucaucuu cgagggccgc uccuacucug      780

ccugcaccac cgacggucgc uccgacggcu ugcccuggug caguaccacg gccaacuacg      840

acaccgacga ccgguuuggc uucugcccca gcgagagacu cuacacccag gacggcaaug      900

cugaugggaa acccugccag uuuccauuca ucuuccaagg ccaauccuac uccgccugca      960

ccacggacgg ucgcuccgac ggcuaccgcu ggugcgccac caccgccaac uacgaccggg     1020

acaagcuguu cggcuucugc ccgacccgag cugacucgac ggugaugggg ggcaacucgg     1080

cgggggagcu gugcgucuuc cccuucacuu uccuggguaa ggaguacucg accuguacca     1140

gcgagggccg cggagauggg cgccucuggu gcgcuaccac cucgaacuuu gacagcgaca     1200

agaagugggg cuucugcccg gaccaaggau acaguuuguu ccucguggcg gcgcaugagu     1260

ucggccacgc gcugggcuua gaucauuccu cagugccgga ggcgcucaug uacccuaugu     1320

accgcuucac ugaggggccc cccuugcaua aggacgacgu gaauggcauc cggcaccucu     1380

augguccucg cccugaaccu gagccacggc cuccaaccac caccacaccg cagcccacgg     1440

cucccccgac ggucugcccc accggacccc ccacugucca ccccucagag cgccccacag     1500

cuggccccac aggucccccc ucagcuggcc ccacaggucc ccccacugcu ggcccuucua     1560

cggccacuac ugugccuuug aguccggugg acgaugccug caacgugaac aucuucgacg     1620

ccaucgcgga gauugggaac cagcuguauu uguucaagga ugggaaguac uggcgauucu     1680

cugagggcag ggggagccgg ccgcagggcc ccuuccuuau cgccgacaag uggcccgcgc     1740

ugccccgcaa gcuggacucg gucuuugagg agcggcucuc caagaagcug uucuucuucu     1800

cugggcgcca ggugugggug uacacaggcg cgucggugcu gggcccgagg cgucuggaca     1860

agcugggccu gggagccgac guggcccagg ugaccggggc ccuccggagu ggcaggggga     1920

agaugcugcu guucagcggg cggcgccucu ggagguucga cgugaaggcg cagauggugg     1980

auccccggag cgccagcgag guggaccgga uguuccccgg ggugccuuug gacacgcacg     2040

acgucuucca guaccgagag aaagccuauu ucugccagga ccgcuucuac uggcgcguga     2100

guucccggag ugaguugaac cagguggacc aagugggcua cgugaccuau gacauccugc     2160

agugcccuga ggacuaggga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2220

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2280

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2340

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc     2460

cccccccccc ccccccccaa aggcucuuuu cagagccacc agaauu                    2506


<210>  6103
<211>  1450
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (wt)

<400>  6103
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggaaa       60

cuccaaacac cacagaggac uaugacacga ccacagaguu ugacuauggg gaugcaacuc      120

cgugccagaa ggugaacgag agggccuuug gggcccaacu gcugcccccu cuguacuccu      180

ugguauuugu cauuggccug guuggaaaca uccugguggu ccugguccuu gugcaauaca      240

agaggcuaaa aaacaugacc agcaucuacc uccugaaccu ggccauuucu gaccugcugu      300

uccuguucac gcuucccuuc uggaucgacu acaaguugaa ggaugacugg guuuuuggug      360

augccaugug uaagauccuc ucuggguuuu auuacacagg cuuguacagc gagaucuuuu      420

ucaucauccu gcugacgauu gacagguacc uggccaucgu ccacgccgug uuugccuugc      480

gggcacggac cgucacuuuu ggugucauca ccagcaucau cauuugggcc cuggccaucu      540

uggcuuccau gccaggcuua uacuuuucca agacccaaug ggaguucacu caccacaccu      600

guagccuuca cuuuccucac gaaagccuac gagaguggaa gcuguuucag gcucugaaac      660

ugaaccucuu ugggcuggua uugccuuugu uggucaugau caucugcuac acagggauua      720

uaaagauucu gcuaagacga ccaaaugaga agaaauccaa agcuguccgu uugauuuuug      780

ucaucaugau caucuuuuuu cucuuuugga cccccuacaa uuugacuaua cuuauuucug      840

uuuuccaaga cuuccuguuc acccaugagu gugagcagag cagacauuug gaccuggcug      900

ugcaagugac ggaggugauc gccuacacgc acugcugugu caacccagug aucuacgccu      960

ucguugguga gagguuccgg aaguaccugc ggcaguuguu ccacaggcgu guggcugugc     1020

accugguuaa auggcucccc uuccucuccg uggacaggcu ggagaggguc agcuccacau     1080

cucccuccac aggggagcau gaacucucug cuggguucug aggacuagug caucacauuu     1140

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1200

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1260

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1320

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaugca uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc     1440

caccagaauu                                                            1450


<210>  6104
<211>  1108
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (wt)

<400>  6104
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaauc       60

gcugcugggc gcuguuccug ucucucugcu gcuaccugcg ucuggucagc gccgaggggg      120

accccauucc cgaggagcuu uaugagaugc ugagugacca cucgauccgc uccuuugaug      180

aucuccaacg ccugcugcac ggagaccccg gagaggaaga uggggccgag uuggaccuga      240

acaugacccg cucccacucu ggaggcgagc uggagagcuu ggcucgugga agaaggagcc      300

uggguucccu gaccauugcu gagccggcca ugaucgccga gugcaagacg cgcaccgagg      360

uguucgagau cucccggcgc cucauagacc gcaccaacgc caacuuccug guguggccgc      420

ccugugugga ggugcagcgc ugcuccggcu gcugcaacaa ccgcaacgug cagugccgcc      480

ccacccaggu gcagcugcga ccuguccagg ugagaaagau cgagauugug cggaagaagc      540

caaucuuuaa gaaggccacg gugacgcugg aagaccaccu ggcaugcaag ugugagacag      600

uggcagcugc acggccugug acccgaagcc cgggggguuc ccaggagcag cgagccaaaa      660

cgccccaaac ucgggugacc auucggacgg ugcgaguccg ccggcccccc aagggcaagc      720

accggaaauu caagcacacg caugacaaga cggcacugaa ggagacccuu ggagccuagg      780

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      840

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      900

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      960

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1080

aaaggcucuu uucagagcca ccagaauu                                        1108


<210>  6105
<211>  1477
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (wt)

<400>  6105
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacc       60

ggcucaucuu ugucuacacu cuaaucugcg caaacuuuug cagcugucgg gacacuucug      120

caaccccgca gagcgcaucc aucaaagcau ugcgcaacgc caaccucagg cgagaugacu      180

uguaccgaag agaugagacc auccagguga aaggaaacgg cuacgugcag aguccuagau      240

ucccgaacag cuaccccagg aaccugcucc ugacauggcg gcuucacucu caggagaaua      300

cacggauaca gcuaguguuu gacaaucagu uuggauuaga ggaagcagaa aaugauaucu      360

guagguauga uuuuguggaa guugaagaua uauccgaaac caguaccauu auuagaggac      420

gauggugugg acacaaggaa guuccuccaa ggauaaaauc aagaacgaac caaauuaaaa      480

ucacauucaa guccgaugac uacuuugugg cuaaaccugg auucaagauu uauuauucuu      540

ugcuggaaga uuuccaaccc gcagcagcuu cagagaccaa cugggaaucu gucacaagcu      600

cuauuucagg gguauccuau aacucuccau caguaacgga ucccacucug auugcggaug      660

cucuggacaa aaaaauugca gaauuugaua caguggaaga ucugcucaag uacuucaauc      720

cagagucaug gcaagaagau cuugagaaua uguaucugga caccccucgg uaucgaggca      780

ggucauacca ugaccggaag ucaaaaguug accuggauag gcucaaugau gaugccaagc      840

guuacaguug cacucccagg aauuacucgg ucaauauaag agaagaacug aaguuggcca      900

auguggucuu cuuuccacgu ugccuccucg ugcagcgcug uggaggaaau uguggcugug      960

gaacugucaa cuggaggucc ugcacaugca auucagggaa aaccgugaaa aaguaucaug     1020

agguauuaca guuugagccu ggccacauca agaggagggg uagagcuaag accauggcuc     1080

uaguugacau ccaguuggau caccaugaac gaugugauug uaucugcagc ucaagaccac     1140

cucgauaagg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1200

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1260

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1320

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc     1440

ccccccccca aaggcucuuu ucagagccac cagaauu                              1477


<210>  6106
<211>  1060
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (wt)

<400>  6106
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugguca       60

cccacagcaa guuucccgcc gccgggauga gccgcccccu ggacaccagc cugcgccuca      120

agaccuucag cuccaagagc gaguaccagc ugguggugaa cgcagugcgc aagcugcagg      180

agagcggcuu cuacuggagc gcagugaccg gcggcgaggc gaaccugcug cucagugccg      240

agcccgccgg caccuuucug auccgcgaca gcucggacca gcgccacuuc uucacgcuca      300

gcgucaagac ccagucuggg accaagaacc ugcgcaucca gugugagggg ggcagcuucu      360

cucugcagag cgauccccgg agcacgcagc ccgugccccg cuucgacugc gugcucaagc      420

uggugcacca cuacaugccg cccccuggag cccccuccuu ccccucgcca ccuacugaac      480

ccuccuccga ggugcccgag cagccgucug cccagccacu cccugggagu ccccccagaa      540

gggccuauua caucuacucc gggggcgaga agaucccccu gguguugagc cggccccucu      600

ccuccaacgu ggccacucuu cagcaucucu gucggaagac cgucaacggc caccuggacu      660

ccuaugagaa agucacccag cugccggggc ccauucggga guuccuggac caguacgaug      720

ccccgcuuua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      780

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      840

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      900

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc     1020

cccccccccc ccaaaggcuc uuuucagagc caccagaauu                           1060


<210>  6107
<211>  1555
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (wt)

<400>  6107
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugccgc       60

ccuccgggcu gcggcugcug ccgcugcugc uaccgcugcu guggcuacug gugcugacgc      120

cuggccggcc ggccgcggga cuauccaccu guaagacuau cgacauggag cuggugaagc      180

ggaagcgcau cgaggccauc cgcggccaga uccuguccaa gcugcggcuc gccagccccc      240

cgagccaggg ggaggugccg cccggcccgc ugcccgaggc cgugcucgcc cuguacaaca      300

gcacccgcga ccggguggcc ggggagagug cagaaccgga gcccgagccu gaggccgacu      360

acuacgccaa ggaggucacc cgcgugcuaa ugguggaaac ccacaacgaa aucuaugaca      420

aguucaagca gaguacacac agcauauaua uguucuucaa cacaucagag cuccgagaag      480

cgguaccuga acccguguug cucucccggg cagagcugcg ucugcugagg cucaaguuaa      540

aaguggagca gcacguggag cuguaccaga aauacagcaa caauuccugg cgauaccuca      600

gcaaccggcu gcuggcaccc agcgacucgc cagagugguu aucuuuugau gucaccggag      660

uugugcggca gugguugagc cguggagggg aaauugaggg cuuucgccuu agcgcccacu      720

gcuccuguga cagcagggau aacacacugc aaguggacau caacggguuc acuaccggcc      780

gccgagguga ccuggccacc auucauggca ugaaccggcc uuuccugcuu cucauggcca      840

ccccgcugga gagggcccag caucugcaaa gcucccggca ccgccgagcc cuggacacca      900

acuauugcuu cagcuccacg gagaagaacu gcugcgugcg gcagcuguac auugacuucc      960

gcaaggaccu cggcuggaag uggauccacg agcccaaggg cuaccaugcc aacuucugcc     1020

ucgggcccug ccccuacauu uggagccugg acacgcagua cagcaagguc cuggcccugu     1080

acaaccagca uaacccgggc gccucggcgg cgccgugcug cgugccgcag gcgcuggagc     1140

cgcugcccau cguguacuac gugggccgca agcccaaggu ggagcagcug uccaacauga     1200

ucgugcgcuc cugcaagugc agcugaggac uagugcauca cauuuaaaag caucucagcc     1260

uaccaugaga auaagagaaa gaaaaugaag aucaauagcu uauucaucuc uuuuucuuuu     1320

ucguuggugu aaagccaaca cccugucuaa aaaacauaaa uuucuuuaau cauuuugccu     1380

cuuuucucug ugcuucaauu aauaaaaaau ggaaagaacc uagaucuaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc     1500

cccccccccc cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu          1555


<210>  6108
<211>  1627
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (wt)

<400>  6108
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugcacu       60

acugugugcu gagcgcuuuu cugauccugc aucuggucac ggucgcgcuc agccugucua      120

ccugcagcac acucgauaug gaccaguuca ugcgcaagag gaucgaggcg auccgcgggc      180

agauccugag caagcugaag cucaccaguc ccccagaaga cuauccugag cccgaggaag      240

uccccccgga ggugauuucc aucuacaaca gcaccaggga cuugcuccag gagaaggcga      300

gccggagggc ggccgccugc gagcgcgaga ggagcgacga agaguacuac gccaaggagg      360

uuuacaaaau agacaugccg cccuucuucc ccuccgaaaa ugccaucccg cccacuuucu      420

acagacccua cuucagaauu guucgauuug acgucucagc aauggagaag aaugcuucca      480

auuuggugaa agcagaguuc agagucuuuc guuugcagaa cccaaaagcc agagugccug      540

aacaacggau ugagcuauau cagauucuca aguccaaaga uuuaacaucu ccaacccagc      600

gcuacaucga cagcaaaguu gugaaaacaa gagcagaagg cgaauggcuc uccuucgaug      660

uaacugaugc uguucaugaa uggcuucacc auaaagacag gaaccuggga uuuaaaauua      720

gcuuacacug ucccugcugc acuuuuguac caucuaauaa uuacaucauc ccaaauaaaa      780

gugaagaacu agaagcaaga uuugcaggua uugauggcac cuccacauau accaguggug      840

aucagaaaac uauaaagucc acuaggaaaa aaaacagugg gaagacccca caucuccugc      900

uaauguuauu gcccuccuac agacuugagu cacaacagac caaccggcgg aagaagcgug      960

cuuuggaugc ggccuauugc uuuagaaaug ugcaggauaa uugcugccua cguccacuuu     1020

acauugauuu caagagggau cuagggugga aauggauaca cgaacccaaa ggguacaaug     1080

ccaacuucug ugcuggagca ugcccguauu uauggaguuc agacacucag cacagcaggg     1140

uccugagcuu auauaauacc auaaauccag aagcaucugc uucuccuugc ugcguguccc     1200

aagauuuaga accucuaacc auucucuacu acauuggcaa aacacccaag auugaacagc     1260

uuucuaauau gauuguaaag ucuugcaaau gcagcuaagg acuagugcau cacauuuaaa     1320

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1380

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1440

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1620

cagaauu                                                               1627


<210>  6109
<211>  1621
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (wt)

<400>  6109
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accaugaaga       60

ugcacuugca aagggcucug gugguccugg cccugcugaa cuuugccacg gucagccucu      120

cucuguccac uugcaccacc uuggacuucg gccacaucaa gaagaagagg guggaagcca      180

uuaggggaca gaucuugagc aagcucaggc ucaccagccc cccugagcca acggugauga      240

cccacguccc cuaucagguc cuggcccuuu acaacagcac ccgggagcug cuggaggaga      300

ugcaugggga gagggaggaa ggcugcaccc aggaaaacac cgagucggaa uacuaugcca      360

aagaaaucca uaaauucgac augauccagg ggcuggcgga gcacaacgaa cuggcugucu      420

gcccuaaagg aauuaccucc aagguuuucc gcuucaaugu guccucagug gagaaaaaua      480

gaaccaaccu auuccgagca gaguuccggg ucuugcgggu gcccaacccc agcucuaagc      540

ggaaugagca gaggaucgag cuguuccaga uccuucggcc agaugagcac auugccaaac      600

agcgcuauau cgguggcaag aaucugccca cacggggcac ugccgagugg cuguccuuug      660

augucacuga cacugugcgu gaguggcugu ugagaagaga guccaacuua ggucuagaaa      720

ucagcauuca cuguccaugu cacaccuuuc agcccaaugg agauauccug gaaaacauuc      780

acgaggugau ggaaaucaaa uucaaaggcg uggacaauga ggaugaccau ggccguggag      840

aucuggggcg ccucaagaag cagaaggauc accacaaccc ucaucuaauc cucaugauga      900

uucccccaca ccggcucgac aacccgggcc agggggguca gaggaagaag cgggcuuugg      960

acaccaauua cugcuuccgc aacuuggagg agaacugcug ugugcgcccc cucuacauug     1020

acuuccgaca ggaucugggc uggaaguggg uccaugaacc uaagggcuac uaugccaacu     1080

ucugcucagg cccuugccca uaccuccgca gugcagacac aacccacagc acggugcugg     1140

gacuguacaa cacucugaac ccugaagcau cugccucgcc uugcugcgug ccccaggacc     1200

uggagccccu gaccauccug uacuauguug ggaggacccc caaaguggag cagcucucca     1260

acaugguggu gaagucuugu aaauguagcu gaggacuagu gcaucacauu uaaaagcauc     1320

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1380

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1440

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc     1560

aucccccccc cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau     1620

u                                                                     1621


<210>  6110
<211>  1768
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (wt)

<400>  6110
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauggcgc       60

ccgucgccgu cugggccgcg cuggccgucg gacuggagcu cugggcugcg gcgcacgccu      120

ugcccgccca gguggcauuu acacccuacg ccccggagcc cgggagcaca ugccggcuca      180

gagaauacua ugaccagaca gcucagaugu gcugcagcaa augcucgccg ggccaacaug      240

caaaagucuu cuguaccaag accucggaca ccguguguga cuccugugag gacagcacau      300

acacccagcu cuggaacugg guucccgagu gcuugagcug uggcucccgc uguagcucug      360

accaggugga aacucaagcc ugcacucggg aacagaaccg caucugcacc uguaggcccg      420

gcugguacug cgcgcugagc aagcaggagg ggugccggcu gugcgcgccg cugcgcaagu      480

gccgcccggg cuucggcgug gccagaccag gaacugaaac aucagacgug gugugcaagc      540

ccugugcccc ggggacguuc uccaacacga cuucauccac ggauauuugc aggccccacc      600

agaucuguaa cgugguggcc aucccuggga augcaagcau ggaugcaguc ugcacgucca      660

cgucccccac ccggaguaug gccccagggg caguacacuu accccagcca guguccacac      720

gaucccaaca cacgcagcca acuccagaac ccagcacugc uccaagcacc uccuuccugc      780

ucccaauggg ccccagcccc ccagcugaag ggagcacugg cgacuucgcu cugccaguug      840

gacugauugu gggugugaca gccuuggguc uacuaauaau aggaguggug aacuguguca      900

ucaugaccca ggugaaaaag aagcccuugu gccugcagag agaagccaag gugccucacu      960

ugccugccga uaaggcccgg gguacacagg gccccgagca gcagcaccuc cugaucacag     1020

cgccgagcuc cagcagcagc ucccuggaga gcucggccag ugcguuggac agaagggcgc     1080

ccacucggaa ccagccacag gcaccaggcg uggaggccag uggggccggg gaggcccggg     1140

ccagcaccgg gagcucagau ucuuccccug guggccaugg gacccagguc aaugucaccu     1200

guaucgugaa cgucuguagc agcucugacc acagcucaca gugcuccucc caagccagcu     1260

ccacaauggg agacacagau uccagccccu cggagucccc gaaggacgag cagguccccu     1320

ucuccaagga ggaaugugcc uuucggucac agcuggagac gccagagacc cugcugggga     1380

gcaccgaaga gaagccccug ccccuuggag ugccugaugc ugggaugaag cccaguuaag     1440

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1500

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1560

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1620

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc     1740

aaaggcucuu uucagagcca ccagaauu                                        1768


<210>  6111
<211>  1447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (wt)

<400>  6111
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu accauguaca       60

gagagugggu aguggugaau guuuucauga uguuguacgu ccagcuggug cagggcucca      120

guaaugaaca uggaccagug aagcgaucau cucaguccac auuggaacga ucugaacagc      180

agaucagggc ugcuucuagu uuggaggaac uacuucgaau uacucacucu gaggacugga      240

agcuguggag augcaggcug aggcucaaaa guuuuaccag uauggacucu cgcucagcau      300

cccaucgguc cacuagguuu gcggcaacuu ucuaugacau ugaaacacua aaaguuauag      360

augaagaaug gcaaagaacu cagugcagcc cuagagaaac gugcguggag guggccagug      420

agcuggggaa gaguaccaac acauucuuca agcccccuug ugugaacgug uuccgaugug      480

guggcuguug caaugaagag agccuuaucu guaugaacac cagcaccucg uacauuucca      540

aacagcucuu ugagauauca gugccuuuga caucaguacc ugaauuagug ccuguuaaag      600

uugccaauca uacagguugu aagugcuugc caacagcccc ccgccaucca uacucaauua      660

ucagaagauc cauccagauc ccugaagaag aucgcuguuc ccauuccaag aaacucuguc      720

cuauugacau gcuaugggau agcaacaaau guaaaugugu uuugcaggag gaaaauccac      780

uugcuggaac agaagaccac ucucaucucc aggaaccagc ucucuguggg ccacacauga      840

uguuugacga agaucguugc gagugugucu guaaaacacc augucccaaa gaucuaaucc      900

agcaccccaa aaacugcagu ugcuuugagu gcaaagaaag ucuggagacc ugcugccaga      960

agcacaagcu auuucaccca gacaccugua gcugugagga cagaugcccc uuucauacca     1020

gaccaugugc aaguggcaaa acagcaugug caaagcauug ccgcuuucca aaggagaaaa     1080

gggcugccca ggggccccac agccgaaaga auccuugagg acuagugcau cacauuuaaa     1140

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1200

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1260

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaugcaucc cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac     1440

cagaauu                                                               1447


<210>  6112
<211>  881
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (wt)

<400>  6112
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuauauaa      180

gacauccgua cacuuccuau ggguacgaac ccaugggugg auggcugcac caccaaauca      240

uacccguggu gucgcagcag acuccccaga gucaugcccu ucagccucau caccacaucc      300

ccauggugcc agcucaacag cccgggaucc cccagcagcc aaugaugcca cuuccuggcc      360

aacacuccau gacuccaacc caacaccacc agccaaaccu cccucugccc gcccagcagc      420

ccuuccagcc ccagcccguc cagccccagc cucaccagcc ccugcagccc cagucaccca      480

ugcaccccau ccagcccuug cugccacagc caccucugcc uccgauguuc uccaugcagu      540

cucugcuucc ugaccugccu cuggaagcau ggccagcaac agacaagacc aagcgggagg      600

aaguggauua aggacuagug caucacauuu aaaagcaucu cagccuacca ugagaauaag      660

agaaagaaaa ugaagaucaa uagcuuauuc aucucuuuuu cuuuuucguu gguguaaagc      720

caacacccug ucuaaaaaac auaaauuucu uuaaucauuu ugccucuuuu cucugugcuu      780

caauuaauaa aaaauggaaa gaaccuagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaagaau u                          881


<210>  6113
<211>  917
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (wt)

<400>  6113
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuucuuugc cugccuuuug ggagcauccc      120

uugcuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccguacacu uccuaugggu      240

acgaacccau ggguggaugg cugcaccacc aaaucauacc cguggugucg cagcagacuc      300

cccagaguca ugcccuucag ccucaucacc acauccccau ggugccagcu caacagcccg      360

ggauccccca gcagccaaug augccacuuc cuggccaaca cuccaugacu ccaacccaac      420

accaccagcc aaaccucccu cugcccgccc agcagcccuu ccagccccag cccguccagc      480

cccagccuca ccagccccug cagccccagu cacccaugca ccccauccag cccuugcugc      540

cacagccacc ucugccuccg auguucucca ugcagucucu gcuuccugac cugccucugg      600

aagcauggcc agcaacagac aagaccaagc gggaggaagu ggauuaagga cuagugcauc      660

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      720

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      780

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      840

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aagaauu                                                     917


<210>  6114
<211>  566
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (wt)

<400>  6114
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccgucucug cuuccugacc      240

ugccucugga agcauggcca gcaacagaca agaccaagcg ggaggaagug gauuaaggac      300

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      360

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      420

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      480

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa aaaaaaaaaa agaauu                                           566


<210>  6115
<211>  959
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (wt)

<400>  6115
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

acuuauacuu ggaggcuauc cguauugaca ggacugcauu cgugcuuacc ccucugaagu      240

gguaccagaa caugauaaga cauccguaca cuuccuaugg uuacgaaccc auggguggau      300

ggcugcacca ccaaaucauu cccguggugu cgcagcagac uccccagagu caugcccuuc      360

agccucauca ccacaucccc auggugccag cucaacagcc cgggaucccc cagcagccaa      420

ugaugccacu uccuggccaa cacuccauga cuccaaccca acaccaccag ccaaaccucc      480

cucugcccgc ccagcagccc uuccagcccc agcccgucca gccccagccu caccagcccc      540

ugcagcccca gucacccaug caccccaucc agcccuugcu gccacagcca ccucugccuc      600

cgauguucuc caugcagucu cugcuuccug accugccucu ggaagcaugg ccagcaacag      660

acaagaccaa gcgggaggaa guggauuaag gacuagugca ucacauuuaa aagcaucuca      720

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu      780

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug      840

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu       959


<210>  6116
<211>  845
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (wt)

<400>  6116
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccgacuccc cagagucaug      240

cccuucagcc ucaucaccac auccccaugg ugccagcuca acagcccggg aucccccagc      300

agccaaugau gccacuuccu ggccaacacu ccaugacucc aacccaacac caccagccaa      360

accucccucu gcccgcccag cagcccuucc agccccagcc cguccagccc cagccucacc      420

agccccugca gccccaguca cccaugcacc ccauccagcc cuugcugcca cagccaccuc      480

ugccuccgau guucuccaug cagucucugc uuccugaccu gccucuggaa gcauggccag      540

caacagacaa gaccaagcgg gaggaagugg auuaaggacu agugcaucac auuuaaaagc      600

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      660

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      720

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

gaauu                                                                  845


<210>  6117
<211>  869
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (wt)

<400>  6117
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccucugaagu gguaccagaa caugauaaga cauccguaca      180

cuuccuaugg guacgaaccc auggguggau ggcugcacca ccaaaucaua cccguggugu      240

cgcagcagac uccccagagu caugcccuuc agccucauca ccacaucccc auggugccag      300

cucaacagcc cgggaucccc cagcagccaa ugaugccacu uccuggccaa cacuccauga      360

cuccaaccca acaccaccag ccaaaccucc cucugcccgc ccagcagccc uuccagcccc      420

agcccgucca gccccagccu caccagcccc ugcagcccca gucacccaug caccccaucc      480

agcccuugcu gccacagcca ccucugccuc cgauguucuc caugcagucu cugcuuccug      540

accugccucu ggaagcaugg ccagcaacag acaagaccaa gcgggaggaa guggauuaag      600

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      660

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      720

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      780

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        869


<210>  6118
<211>  3308
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (wt)

<400>  6118
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg cccgccugcc gcugcugcuc gggcugcugc      120

ugcucccgcg ucccggccgg ccgcuggacu uggccgacua caccuaugac cuggcggagg      180

aggacgacuc ggagccccuc aacuacaaag accccugcaa ggcggcugcc uuucuugggg      240

acauugcccu ggacgaagag gaccugaggg ccuuccaggu acagcaggcu guggaucuca      300

gacggcacac agcucguaag uccuccauca aagcugcagu uccaggaaac acuucuaccc      360

ccagcugcca gagcaccaac gggcagccuc agaggggagc cugugggaga uggagaggua      420

gaucccguag ccggcgggcg gcgacguccc gaccagagcg uguguggccc gaugggguca      480

uccccuuugu cauuggggga aacuucacug guagccagag ggcagucuuc cggcaggcca      540

ugaggcacug ggagaagcac accuguguca ccuuccugga gcgcacugac gaggacagcu      600

auauuguguu caccuaucga ccuugcgggu gcugcuccua cgugggucgc cgcggcgggg      660

gcccccaggc caucuccauc ggcaagaacu gugacaaguu cggcauugug guccacgagc      720

ugggccacgu cgucggcuuc uggcacgaac acacucggcc agaccgggac cgccacguuu      780

ccaucguucg ugagaacauc cagccagggc aggaguauaa cuuccugaag auggagccuc      840

aggaggugga gucccugggg gagaccuaug acuucgacag caucaugcau uacgcucgga      900

acacauucuc caggggcauc uuccuggaua ccauuguccc caaguaugag gugaacgggg      960

ugaaaccucc cauuggccaa aggacacggc ucagcaaggg ggacauugcc caagcccgca     1020

agcuguacaa gugcccagcc uguggagaga cccugcaaga cagcacaggc aacuucuccu     1080

ccccugaaua ccccaauggc uacucugcuc acaugcacug cguguggcgc aucucuguca     1140

cacccgggga gaagaucauc cugaacuuca cgucccugga ccuguaccgc agccgccugu     1200

gcugguacga cuauguggag guccgagaug gcuucuggag gaaggcgccc cuccgaggcc     1260

gcuucugcgg guccaaacuc ccugagccua ucgucuccac ugacagccgc cucuggguug     1320

aguuccgcag cagcagcaau uggguuggaa agggcuucuu ugcagucuac gaagccaucu     1380

gcggggguga ugugaaaaag gacuauggcc acauucaauc gcccaacuac ccagacgauu     1440

accggcccag caaagucugc aucuggcgga uccagguguc ugagggcuuc cacgugggcc     1500

ucacauucca guccuuugag auugagcgcc acgacagcug ugccuacgac uaucuggagg     1560

ugcgcgacgg gcacagugag agcagcaccc ucaucgggcg cuacuguggc uaugagaagc     1620

cugaugacau caagagcacg uccagccgcc ucuggcucaa guucgucucu gacgggucca     1680

uuaacaaagc gggcuuugcc gucaacuuuu ucaaagaggu ggacgagugc ucucggccca     1740

accgcggggg cugugagcag cggugccuca acacccuggg cagcuacaag ugcagcugug     1800

accccgggua cgagcuggcc ccagacaagc gccgcuguga ggcugcuugu ggcggauucc     1860

ucaccaagcu caacggcucc aucaccagcc cgggcuggcc caaggaguac ccccccaaca     1920

agaacugcau cuggcagcug guggccccca cccaguaccg caucucccug caguuugacu     1980

ucuuugagac agagggcaau gaugugugca aguacgacuu cguggaggug cgcaguggac     2040

ucacagcuga cuccaagcug cauggcaagu ucugugguuc ugagaagccc gaggucauca     2100

ccucccagua caacaacaug cgcguggagu ucaaguccga caacaccgug uccaaaaagg     2160

gcuucaaggc ccacuucuuc ucagacaagg acgagugcuc caaggauaac ggcggcugcc     2220

agcaggacug cgucaacacg uucggcaguu augagugcca augccgcagu ggcuucgucc     2280

uccaugacaa caagcacgac ugcaaagaag ccggcuguga ccacaaggug acauccacca     2340

gugguaccau caccagcccc aacuggccug acaaguaucc cagcaagaag gagugcacgu     2400

gggccaucuc cagcaccccc gggcaccggg ucaagcugac cuucauggag auggacaucg     2460

agucccagcc ugagugugcc uacgaccacc uagagguguu cgacgggcga gacgccaagg     2520

cccccguccu cggccgcuuc ugugggagca agaagcccga gcccguccug gccacaggca     2580

gccgcauguu ccugcgcuuc uacucagaua acucggucca gcgaaagggc uuccaggccu     2640

cccacgccac agagugcggg ggccagguac gggcagacgu gaagaccaag gaccuuuacu     2700

cccacgccca guuuggcgac aacaacuacc cugggggugu ggacugugag ugggucauug     2760

uggccgagga aggcuacggc guggagcucg uguuccagac cuuugaggug gaggaggaga     2820

ccgacugcgg cuaugacuac auggagcugu ucgacggcua cgacagcaca gcccccaggc     2880

uggggcgcua cuguggcuca gggccuccug aggaggugua cucggcggga gauucugucc     2940

uggugaaguu ccacucggau gacaccauca ccaaaaaagg uuuccaccuc cgauacacca     3000

gcaccaaguu ccaggacaca cuccacagca ggaagugagg acuagugcau cacauuuaaa     3060

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     3120

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     3180

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaagaauu                                                              3308


<210>  6119
<211>  1538
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (wt)

<400>  6119
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggga cccgcugucu ucuagcguug cugcuucccc      120

agguccuccu gggcggcgcg gcuggccucg uuccggagcu gggccgcagg aaguucgcgg      180

cggcgucguc gggccgcccc ucaucccagc ccucugacga gguccugagc gaguucgagu      240

ugcggcugcu cagcauguuc ggccugaaac agagacccac ccccagcagg gacgccgugg      300

ugccccccua caugcuagac cuguaucgca ggcacucagg ucagccgggc ucacccgccc      360

cagaccaccg guuggagagg gcagccagcc gagccaacac ugugcgcagc uuccaccaug      420

aagaaucuuu ggaagaacua ccagaaacga gugggaaaac aacccggaga uucuucuuua      480

auuuaaguuc uauccccacg gaggaguuua ucaccucagc agagcuucag guuuuccgag      540

aacagaugca agaugcuuua ggaaacaaua gcaguuucca ucaccgaauu aauauuuaug      600

aaaucauaaa accugcaaca gccaacucga aauuccccgu gaccagacuu uuggacacca      660

gguuggugaa ucagaaugca agcagauggg aaaguuuuga ugucaccccc gcugugaugc      720

gguggacugc acagggacac gccaaccaug gauucguggu ggaaguggcc cacuuggagg      780

agaaacaagg ugucuccaag agacauguua ggauaagcag gucuuugcac caagaugaac      840

acagcugguc acagauaagg ccauugcuag uaacuuuugg ccaugaugga aaagggcauc      900

cucuccacaa aagagaaaaa cgucaagcca aacacaaaca gcggaaacgc cuuaagucca      960

gcuguaagag acacccuuug uacguggacu ucagugacgu gggguggaau gacuggauug     1020

uggcuccccc gggguaucac gccuuuuacu gccacggaga augcccuuuu ccucuggcug     1080

aucaucugaa cuccacuaau caugccauug uucagacguu ggucaacucu guuaacucua     1140

agauuccuaa ggcaugcugu gucccgacag aacucagugc uaucucgaug cuguaccuug     1200

acgagaauga aaagguugua uuaaagaacu aucaggacau gguuguggag gguugugggu     1260

gucgcuaggg acuagugcau cacauuuaaa agcaucucag ccuaccauga gaauaagaga     1320

aagaaaauga agaucaauag cuuauucauc ucuuuuucuu uuucguuggu guaaagccaa     1380

cacccugucu aaaaaacaua aauuucuuua aucauuuugc cucuuuucuc ugugcuucaa     1440

uuaauaaaaa auggaaagaa ccuagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaagaauu                             1538


<210>  6120
<211>  1574
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (wt)

<400>  6120
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auuccuggua accgaaugcu gauggucguu uuauuaugcc      120

aaguccugcu aggaggcgcg agccaugcua guuugauacc ugagacgggg aagaaaaaag      180

ucgccgagau ucagggccac gcgggaggac gccgcucagg gcagagccau gagcuccugc      240

gggacuucga ggcgacacuu cugcagaugu uugggcugcg ccgccgcccg cagccuagca      300

agagugccgu cauuccggac uacaugcggg aucuuuaccg gcuucagucu ggggaggagg      360

aggaagaaca gauccacagc acuggucuug aguauccuga gcgcccggcc agccgggcca      420

acaccgugag gagcuuccac cacgaagaac aucuggagaa caucccaggg accagugaaa      480

acucugcuuu ucguuuccuc uuuaaccuca gcagcauccc ugagaacgag gugaucuccu      540

cugcagagcu ucggcuguuc cgggagcagg ucgaccaggg cccugauugg gaaaggggcu      600

uccaccguau aaacauuuau gagguuauga agcccccagc agaaguggug ccugggcacc      660

ucaucacacg acuacuggac acgagacugg uccaccacaa ugugacacgg ugggaaacuu      720

uugaugugag cccugcgguc cuucgcugga cccgggagaa gcagccaaac uaugggcuag      780

ccauugaggu gacucaccuc caucagacuc ggacccacca gggccagcau gucaggauua      840

gccgaucguu accucaaggg agugggaauu gggcccagcu ccggccccuc cuggucaccu      900

uuggccauga uggccggggc caugccuuga cccgacgccg gagggccaag cguagcccua      960

agcaucacuc acagcgggcc aggaagaaga auaagaacug ccggcgccac ucgcucuaug     1020

uggacuucag cgaugugggc uggaaugacu ggauuguggc cccaccaggc uaccaggccu     1080

ucuacugcca uggggacugc cccuuuccac uggcugacca ccucaacuca accaaccaug     1140

ccauugugca gacccugguc aauucuguca auuccaguau ccccaaagcc uguugugugc     1200

ccacugaacu gagugccauc uccaugcugu accuggauga guaugauaag gugguacuga     1260

aaaauuauca ggagauggua guagagggau gugggugccg cugaggacua gugcaucaca     1320

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1380

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1440

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1500

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaag aauu                                                       1574


<210>  6121
<211>  1889
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (wt)

<400>  6121
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggggcugg ggcggagggc gcaguggcug ugcugguggu      120

gggggcugcu gugcagcugc ugcgggcccc cgccgcugcg gccgcccuug cccgcugccg      180

cggccgccgc cgccgggggg cagcugcugg gggacggcgg gagccccggc cgcacggagc      240

agccgccgcc gucgccgcag uccuccucgg gcuuccugua ccggcggcuc aagacgcagg      300

agaagcggga gaugcagaag gagaucuugu cggugcuggg gcucccgcac cggccccggc      360

cccugcacgg ccuccaacag ccgcagcccc cggcgcuccg gcagcaggag gagcagcagc      420

agcagcagca gcugccucgc ggagagcccc cucccgggcg acugaagucc gcgccccucu      480

ucaugcugga ucuguacaac gcccuguccg ccgacaacga cgaggacggg gcgucggagg      540

gggagaggca gcaguccugg ccccacgaag cagccagcuc gucccagcgu cggcagccgc      600

ccccgggcgc cgcgcacccg cucaaccgca agagccuucu ggcccccgga ucuggcagcg      660

gcggcgcguc cccacugacc agcgcgcagg acagcgccuu ccucaacgac gcggacaugg      720

ucaugagcuu ugugaaccug guggaguacg acaaggaguu cuccccucgu cagcgacacc      780

acaaagaguu caaguucaac uuaucccaga uuccugaggg ugagguggug acggcugcag      840

aguuccgcau cuacaaggac uguguuaugg ggaguuuuaa aaaccaaacu uuucuuauca      900

gcauuuauca agucuuacag gagcaucagc acagagacuc ugaccuguuu uuguuggaca      960

cccguguagu augggccuca gaagaaggcu ggcuggaauu ugacaucacg gccacuagca     1020

aucugugggu ugugacucca cagcauaaca uggggcuuca gcugagcgug gugacaaggg     1080

auggagucca cguccacccc cgagccgcag gccugguggg cagagacggc ccuuacgaca     1140

agcagcccuu caugguggcu uucuucaaag ugagugaggu gcacgugcgc accaccaggu     1200

cagccuccag ccggcgccga caacagaguc guaaucgcuc uacccagucc caggacgugg     1260

cgcgggucuc cagugcuuca gauuacaaca gcagugaauu gaaaacagcc ugcaggaagc     1320

augagcugua ugugaguuuc caagaccugg gauggcagga cuggaucauu gcacccaagg     1380

gcuaugcugc caauuacugu gauggagaau gcuccuuccc acucaacgca cacaugaaug     1440

caaccaacca cgcgauugug cagaccuugg uucaccuuau gaaccccgag uaugucccca     1500

aaccgugcug ugcgccaacu aagcuaaaug ccaucucggu ucuuuacuuu gaugacaacu     1560

ccaaugucau ucugaaaaaa uacaggaaua ugguuguaag agcuugugga ugccacuaag     1620

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug     1680

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc     1740

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa     1800

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                       1889


<210>  6122
<211>  1643
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (wt)

<400>  6122
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugcgcu cacugcgagc ugcggcgccg cacagcuucg      120

uggcgcucug ggcaccccug uuccugcugc gcuccgcccu ggccgacuuc agccuggaca      180

acgaggugca cucgagcuuc auccaccggc gccuccgcag ccaggagcgg cgggagaugc      240

agcgcgagau ccucuccauu uugggcuugc cccaccgccc gcgcccgcac cuccagggca      300

agcacaacuc ggcacccaug uucaugcugg accuguacaa cgccauggcg guggaggagg      360

gcggcgggcc cggcggccag ggcuucuccu accccuacaa ggccgucuuc aguacccagg      420

gccccccucu ggccagccug caagauagcc auuuccucac cgacgccgac auggucauga      480

gcuucgucaa ccucguggaa caugacaagg aguucuucca cccacgcuac caccaucgag      540

aguuccgguu ugaucuuucc aagaucccag aaggggaagc ugucacggca gccgaguucc      600

ggaucuacaa ggacuacauc cgggaacgcu ucgacaauga gacguuccgg aucagcguuu      660

aucaggugcu ccaggagcac uugggcaggg aaucggaucu cuuccugcuc gacagccgua      720

cccucugggc cucggaggag ggcuggcugg uguuugacau cacagccacc agcaaccacu      780

ggguggucaa uccgcggcac aaccugggcc ugcagcucuc gguggagacg cuggaugggc      840

agagcaucaa ccccaaguug gcgggccuga uugggcggca cgggccccag aacaagcagc      900

ccuucauggu ggcuuucuuc aaggccacgg agguccacuu ccgcagcauc cgguccacgg      960

ggagcaaaca gcgcagccag aaccgcucca agacgcccaa gaaccaggaa gcccugcgga     1020

uggccaacgu ggcagagaac agcagcagcg accagaggca ggccuguaag aagcacgagc     1080

uguaugucag cuuccgagac cugggcuggc aggacuggau caucgcgccu gaaggcuacg     1140

ccgccuacua cugugagggg gagugugccu ucccucugaa cuccuacaug aacgccacca     1200

accacgccau cgugcagacg cugguccacu ucaucaaccc ggaaacggug cccaagcccu     1260

gcugugcgcc cacgcagcuc aaugccaucu ccguccucua cuucgaugac agcuccaacg     1320

ucauccugaa gaaauacaga aacauggugg uccgggccug uggcugccac uagggacuag     1380

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc     1440

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa     1500

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga     1560

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaaa aaaaaaaaga auu                                             1643


<210>  6123
<211>  647
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (wt)

<400>  6123
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagccucug cagcacuucu gugucugcug cucacagcag      120

cugcuuucag cccccagggg cuugcucagc caguugggau uaauacuuca acuaccugcu      180

gcuacagauu uaucaauaag aaaaucccua agcagaggcu ggagagcuac agaaggacca      240

ccaguagcca cuguccccgg gaagcuguaa ucuucaagac caaacuggac aaggagaucu      300

gugcugaccc cacacagaag uggguccagg acuuuaugaa gcaccuggac aagaaaaccc      360

aaacuccaaa gcugugagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag      420

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug      480

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu      540

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa      600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                    647


<210>  6124
<211>  3971
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (wt)

<400>  6124
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucacuc uuaucauucu guugccagua guuucaaaau      120

uuaguuuugu uagucucuca gcaccgcagc acuggagcug uccugaaggu acucucgcag      180

gaaauggcaa uucuacuugu guggguccug cacccuucuu aauuuucucc cauggaaaua      240

guaucuuuag gauugacaca gaaggaacca auuaugagca auugguggug gaugcuggug      300

ucucagugau cauggauuuu cauuauaaug agaaaagaau cuauugggug gauuuagaaa      360

gacaacuuuu gcaaagaguu uuucugaaug ggucaaggca agagagagua uguaauauag      420

agaaaaaugu uucuggaaug gcaauaaauu ggauaaauga agaaguuauu uggucaaauc      480

aacaggaagg aaucauuaca guaacagaua ugaaaggaaa uaauucccac auucuuuuaa      540

gugcuuuaaa auauccugca aauguagcag uugauccagu agaaagguuu auauuuuggu      600

cuucagaggu ggcuggaagc cuuuauagag cagaucucga ugguguggga gugaaggcuc      660

uguuggagac aucagagaaa auaacagcug ugucauugga ugugcuugau aagcggcugu      720

uuuggauuca guacaacaga gaaggaagca auucucuuau uugcuccugu gauuaugaug      780

gagguucugu ccacauuagu aaacauccaa cacagcauaa uuuguuugca augucccuuu      840

uuggugaccg uaucuucuau ucaacaugga aaaugaagac aauuuggaua gccaacaaac      900

acacuggaaa ggacaugguu agaauuaacc uccauucauc auuuguacca cuuggugaac      960

ugaaaguagu gcauccacuu gcacaaccca aggcagaaga ugacacuugg gagccugagc     1020

agaaacuuug caaauugagg aaaggaaacu gcagcagcac uguguguggg caagaccucc     1080

agucacacuu gugcaugugu gcagagggau acgcccuaag ucgagaccgg aaguacugug     1140

aagauguuaa ugaaugugcu uuuuggaauc auggcuguac ucuugggugu aaaaacaccc     1200

cuggauccua uuacugcacg ugcccuguag gauuuguucu gcuuccugau gggaaacgau     1260

gucaucaacu uguuuccugu ccacgcaaug ugucugaaug cagccaugac uguguucuga     1320

caucagaagg ucccuuaugu uucuguccug aaggcucagu gcuugagaga gaugggaaaa     1380

cauguagcgg uuguuccuca cccgauaaug guggauguag ccagcucugc guuccucuua     1440

gcccaguauc cugggaaugu gauugcuuuc cuggguauga ccuacaacug gaugaaaaaa     1500

gcugugcagc uucaggacca caaccauuuu ugcuguuugc caauucucaa gauauucgac     1560

acaugcauuu ugauggaaca gacuauggaa cucugcucag ccagcagaug ggaaugguuu     1620

augcccuaga ucaugacccu guggaaaaua agauauacuu ugcccauaca gcccugaagu     1680

ggauagagag agcuaauaug gaugguuccc agcgagaaag gcuuauugag gaaggaguag     1740

augugccaga aggucuugcu guggacugga uuggccguag auucuauugg acagacagag     1800

ggaaaucucu gauuggaagg agugauuuaa augggaaacg uuccaaaaua aucacuaagg     1860

agaacaucuc ucaaccacga ggaauugcug uucauccaau ggccaagaga uuauucugga     1920

cugauacagg gauuaaucca cgaauugaaa guucuucccu ccaaggccuu ggccgucugg     1980

uuauagccag cucugaucua aucuggccca guggaauaac gauugacuuc uuaacugaca     2040

aguuguacug gugcgaugcc aagcagucug ugauugaaau ggccaaucug gaugguucaa     2100

aacgccgaag acuuacccag aaugauguag gucacccauu ugcuguagca guguuugagg     2160

auuaugugug guucucagau ugggcuaugc caucaguaau gagaguaaac aagaggacug     2220

gcaaagauag aguacgucuc caaggcagca ugcugaagcc cucaucacug guugugguuc     2280

auccauuggc aaaaccagga gcagaucccu gcuuauauca aaacggaggc ugugaacaua     2340

uuugcaaaaa gaggcuugga acugcuuggu guucgugucg ugaagguuuu augaaagccu     2400

cagaugggaa aacgugucug gcucuggaug gucaucagcu guuggcagga ggugaaguug     2460

aucuaaagaa ccaaguaaca ccauuggaca ucuuguccaa gacuagagug ucagaagaua     2520

acauuacaga aucucaacac augcuagugg cugaaaucau ggugucagau caagaugacu     2580

gugcuccugu gggaugcagc auguaugcuc gguguauuuc agagggagag gaugccacau     2640

gucaguguuu gaaaggauuu gcuggggaug gaaaacuaug uucugauaua gaugaaugug     2700

agaugggugu cccagugugc cccccugccu ccuccaagug caucaacacc gaaggugguu     2760

augucugccg gugcucagaa ggcuaccaag gagaugggau ucacugucuu gauauugaug     2820

agugccaacu gggggagcac agcuguggag agaaugccag cugcacaaau acagagggag     2880

gcuauaccug caugugugcu ggacgccugu cugaaccagg acugauuugc ccugacucua     2940

cuccaccccc ucaccucagg gaagaugacc accacuauuc cguaagaaau agugacucug     3000

aauguccccu gucccacgau ggguacugcc uccaugaugg ugugugcaug uauauugaag     3060

cauuggacaa guaugcaugc aacuguguug uuggcuacau cggggagcga ugucaguacc     3120

gagaccugaa guggugggaa cugcgccacg cuggccacgg gcagcagcag aaggucaucg     3180

ugguggcugu cugcguggug gugcuuguca ugcugcuccu ccugagccug uggggggccc     3240

acuacuacag gacucagaag cugcuaucga aaaacccaaa gaauccuuau gaggagucga     3300

gcagagaugu gaggagucgc aggccugcug acacugagga ugggaugucc ucuugcccuc     3360

aaccuugguu ugugguuaua aaagaacacc aagaccucaa gaaugggggu caaccagugg     3420

cuggugagga uggccaggca gcagaugggu caaugcaacc aacuucaugg aggcaggagc     3480

cccaguuaug uggaaugggc acagagcaag gcugcuggau uccaguaucc agugauaagg     3540

gcuccugucc ccagguaaug gagcggagcu uucauaugcc cuccuauggg acacagaccc     3600

uugaaggggg ugucgagaag ccccauucuc uccuaucagc uaacccauua uggcaacaaa     3660

gggcccugga cccaccacac caaauggagc ugacucagug aggacuagug caucacauuu     3720

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     3780

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     3840

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     3900

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3960

aaaaaagaau u                                                          3971


<210>  6125
<211>  857
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (wt)

<400>  6125
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgcgggga ggaggaugga gaugcucugu gccggcaggg      120

ucccugcgcu gcugcucugc cuggguuucc aucuucuaca ggcaguccuc aguacaacug      180

ugauuccauc auguauccca ggagagucca gugauaacug cacagcuuua guucagacag      240

aagacaaucc acguguggcu caagugucaa uaacaaagug uagcucugac augaauggcu      300

auuguuugca uggacagugc aucuaucugg uggacaugag ucaaaacuac ugcagaugug      360

aaguggguua uacugguguc cgaugugaac acuucuuuuu aaccguccac caaccuuuaa      420

gcaaagaaua uguggcuuug accgugauuc uuauuauuuu guuucuuauc acagucgucg      480

guuccacaua uuauuucugc agaugguaca gaaaucgaaa aaguaaagaa ccaaagaagg      540

aauaugagag aguuaccuca ggggauccag aguugccgca agucugagga cuagugcauc      600

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc      660

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa      720

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac      780

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa aagaauu                                                     857


<210>  6126
<211>  1214
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (wt)

<400>  6126
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggugugg gggguggaga uguagaagau gugacgccgc      120

ggcccggcgg gugccagauu agcggacgcg gugcccgcgg uugcaacggg aucccgggcg      180

cugcagcuug ggaggcggcu cuccccaggc ggcguccgcg gagacaccca uccgugaacc      240

ccaggucccg ggccgccggc ucgccgcgca ccaggggccg gcggacagaa gaacggccga      300

gcggcucgag gcugggggac cgcgggcgcg gccgcgcgcu gccgggcggg aggcuggggg      360

gccggggccg gggccgugcc ccggagcggg ucggaggccg gggccggggc cgggggacgg      420

cggcuccccg cgcggcucca gcggcucggg gaucccggcc gggccccgca gggaccaugg      480

cagccgggag caucaccacg cugcccgccu ugcccgagga uggcggcagc ggcgccuucc      540

cgcccggcca cuucaaggac cccaagcggc uguacugcaa aaacgggggc uucuuccugc      600

gcauccaccc cgacggccga guugacgggg uccgggaaaa gagcgacccu cacaucaagc      660

uacaacuuca agcagaagag agaggaguug ugucuaucaa aggagugugu gcuaaccguu      720

accuggcuau gaaggaagau ggaagauuac uggcuucuaa auguguuacg gaugaguguu      780

ucuuuuuuga acgauuggaa ucuaauaacu acaauacuua ccggucaagg aaauacacca      840

guugguaugu ggcacugaaa cgaacugggc aguauaaacu uggauccaaa acaggaccug      900

ggcagaaagc uauacuuuuu cuuccaaugu cugcuaagag cugaggacua gugcaucaca      960

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     1020

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     1080

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     1140

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1200

aaaaaaaaag aauu                                                       1214


<210>  6127
<211>  932
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (wt)

<400>  6127
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uacugacaug gauccugcca acuuugcucu      120

acagaucaug cuuucacauu aucugucuag uggguacuau aucuuuagcu ugcaaugaca      180

ugacuccaga gcaaauggcu acaaauguga acuguuccag cccugagcga cacacaagaa      240

guuaugauua cauggaagga ggggauauaa gagugagaag acucuucugu cgaacacagu      300

gguaccugag gaucgauaaa agaggcaaag uaaaagggac ccaagagaug aagaauaauu      360

acaauaucau ggaaaucagg acaguggcag uuggaauugu ggcaaucaaa gggguggaaa      420

gugaguucua ucuugcaaug aacaaggaag gaaaacucua ugcaaagaaa gaaugcaaug      480

aagauuguaa cuucaaagaa cuaauucugg aaaaccauua caacacauau gcaucagcua      540

aauggacaca caacggaggg gaaauguuug uugccuuaaa ucaaaagggg auuccuguaa      600

gaggaaaaaa aacgaagaaa gaacaaaaaa cagcccacuu ucuuccuaug gcaauaacuu      660

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa      720

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu      780

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua      840

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                    932


<210>  6128
<211>  2534
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (wt)

<400>  6128
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca aacuccugcc agcccugcug cugcagcaug      120

uccuccugca ucuccuccug cuccccaucg ccauccccua ugcagaggga caaaggaaaa      180

gaagaaauac aauucaugag uucaaaaaau cagcaaagac uacccuaauc aaaauagauc      240

cagcacugaa gauaaaaacc aaaaaaguga auacugcaga ccaaugugcu aauagaugua      300

cuaggaauaa aggacuucca uucacuugca aggcuuuugu uuuugauaaa gcaagaaaac      360

aaugccucug guuccccuuc aauagcaugu caaguggagu gaaaaaagaa uuuggccaug      420

aauuugaccu cuaugaaaac aaagacuaca uuagaaacug caucauuggu aaaggacgca      480

gcuacaaggg aacaguaucu aucacuaaga guggcaucaa augucagccc uggaguucca      540

ugauaccaca cgaacacagc uuuuugccuu cgagcuaucg ggguaaagac cuacaggaaa      600

acuacugucg aaauccucga ggggaagaag ggggacccug guguuucaca agcaauccag      660

agguacgcua cgaagucugu gacauuccuc aguguucaga aguugaaugc augaccugca      720

auggggagag uuaucgaggu cucauggauc auacagaauc aggcaagauu ugucagcgcu      780

gggaucauca gacaccacac cggcacaaau ucuugccuga aagauauccc gacaagggcu      840

uugaugauaa uuauugccgc aaucccgaug gccagccgag gccauggugc uauacucuug      900

acccucacac ccgcugggag uacugugcaa uuaaaacaug cgcugacaau acuaugaaug      960

acacugaugu uccuuuggaa acaacugaau gcauccaagg ucaaggagaa ggcuacaggg     1020

gcacugucaa uaccauuugg aauggaaucc caugucagcg uugggauucu caguauccuc     1080

acgagcauga caugacuccu gaaaauuuca agugcaagga ccuacgagaa aauuacugcc     1140

gaaauccaga ugggucugaa ucacccuggu guuuuaccac ugauccaaac auccgaguug     1200

gcuacugcuc ccaaauucca aacugugaua ugucacaugg acaagauugu uaucguggga     1260

auggcaaaaa uuauaugggc aacuuauccc aaacaagauc uggacuaaca uguucaaugu     1320

gggacaagaa cauggaagac uuacaucguc auaucuucug ggaaccagau gcaaguaagc     1380

ugaaugagaa uuacugccga aauccagaug augaugcuca uggacccugg ugcuacacgg     1440

gaaauccacu cauuccuugg gauuauugcc cuauuucucg uugugaaggu gauaccacac     1500

cuacaauagu caauuuagac caucccguaa uaucuugugc caaaacgaaa caauugcgag     1560

uuguaaaugg gauuccaaca cgaacaaaca uaggauggau gguuaguuug agauacagaa     1620

auaaacauau cugcggagga ucauugauaa aggagaguug gguucuuacu gcacgacagu     1680

guuucccuuc ucgagacuug aaagauuaug aagcauggcu uggaauccau gauguccacg     1740

gaagaggaga ugagaaaugc aaacagguuc ucaauguuuc ccagcuggua uauggcccug     1800

aaggaucaga ucugguuuua augaagcugg ccaggccugc uguccuggau gauuuuguua     1860

guacgauuga uuuaccuaau uauggaugca caauuccuga aaagaccagu ugcaguguuu     1920

auggcugggg cuacacugga uugaucaacu augauggccu auuacgagug gcacaucucu     1980

auauaauggg aaaugagaaa ugcagccagc aucaucgagg gaaggugacu cugaaugagu     2040

cugaaauaug ugcuggggcu gaaaagauug gaucaggacc augugagggg gauuauggug     2100

gcccacuugu uugugagcaa cauaaaauga gaaugguucu uggugucauu guuccugguc     2160

guggaugugc cauuccaaau cguccuggua uuuuuguccg aguagcauau uaugcaaaau     2220

ggauacacaa aauuauuuua acauauaagg uaccacaguc auagggacua gugcaucaca     2280

uuuaaaagca ucucagccua ccaugagaau aagagaaaga aaaugaagau caauagcuua     2340

uucaucucuu uuucuuuuuc guugguguaa agccaacacc cugucuaaaa aacauaaauu     2400

ucuuuaauca uuuugccucu uuucucugug cuucaauuaa uaaaaaaugg aaagaaccua     2460

gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaag aauu                                                       2534


<210>  6129
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (wt)

<400>  6129
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaagccg cggcgaucgg caucgaccug ggcaccaccu      120

acuccugcgu ggggguguuc caacacggca agguggagau caucgccaac gaccagggca      180

accgcaccac ccccagcuac guggccuuca cggacaccga gcggcucauc ggggaugcgg      240

ccaagaacca gguggcgcug aacccgcaga acaccguguu ugacgcgaag cggcugauug      300

gccgcaaguu cggcgacccg guggugcagu cggacaugaa gcacuggccu uuccagguga      360

ucaacgacgg agacaagccc aaggugcagg ucagcuacaa gggggagacc aaggcauucu      420

accccgagga gaucucgucc auggugcuga ccaagaugaa ggagaucgcc gaggcguacc      480

ugggcuaccc ggugaccaac gcggugauca ccgugccggc cuacuucaac gacucgcagc      540

gccaggccac caaggaugcg ggugugaucg cggggcucaa cgugcugcgg aucaucaacg      600

agcccacggc cgccgccauc gccuacggcc uggacagaac gggcaagggg gagcgcaacg      660

ugcucaucuu ugaccugggc gggggcaccu ucgacguguc cauccugacg aucgacgacg      720

gcaucuucga ggugaaggcc acggccgggg acacccaccu ggguggggag gacuuugaca      780

acaggcuggu gaaccacuuc guggaggagu ucaagagaaa acacaagaag gacaucagcc      840

agaacaagcg agccgugagg cggcugcgca ccgccugcga gagggccaag aggacccugu      900

cguccagcac ccaggccagc cuggagaucg acucccuguu ugagggcauc gacuucuaca      960

cguccaucac cagggcgagg uucgaggagc ugugcuccga ccuguuccga agcacccugg     1020

agcccgugga gaaggcucug cgcgacgcca agcuggacaa ggcccagauu cacgaccugg     1080

uccuggucgg gggcuccacc cgcaucccca aggugcagaa gcugcugcag gacuucuuca     1140

acgggcgcga ccugaacaag agcaucaacc ccgacgaggc uguggccuac ggggcggcgg     1200

ugcaggcggc cauccugaug ggggacaagu ccgagaacgu gcaggaccug cugcugcugg     1260

acguggcucc ccugucgcug gggcuggaga cggccggagg cgugaugacu gcccugauca     1320

agcgcaacuc caccaucccc accaagcaga cgcagaucuu caccaccuac uccgacaacc     1380

aacccggggu gcugauccag guguacgagg gcgagagggc caugacgaaa gacaacaauc     1440

uguuggggcg cuucgagcug agcggcaucc cuccggcccc caggggcgug ccccagaucg     1500

aggugaccuu cgacaucgau gccaacggca uccugaacgu cacggccacg gacaagagca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg ccgccugagc aaggaggaga     1620

ucgagcgcau ggugcaggag gcggagaagu acaaagcgga ggacgaggug cagcgcgaga     1680

gggugucagc caagaacgcc cuggaguccu acgccuucaa caugaaaagc gccguggagg     1740

augaggggcu caagggcaag aucagcgagg cggacaagaa gaaggugcug gacaaguguc     1800

aagaggucau cucguggcug gacgccaaca ccuuggccga gaaggacgag uuugagcaca     1860

agaggaagga gcuggagcag gucuguaacc ccaucaucag cggacuguac cagggugccg     1920

guggucccgg gccugggggc uucggggcuc agggucccaa gggagggucu gggucaggcc     1980

ccaccauuga ggagguagau uagggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  6130
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (wt)

<400>  6130
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaagccg cggcgaucgg caucgaccug ggcaccaccu      120

acuccugcgu ggggguguuc caacacggca agguggagau caucgccaac gaccagggca      180

accgcaccac ccccagcuac guggccuuca cggacaccga gcggcucauc ggggaugcgg      240

ccaagaacca gguggcgcug aacccgcaga acaccguguu ugacgcgaag cggcugauug      300

gccgcaaguu cggcgacccg guggugcagu cggacaugaa gcacuggccu uuccagguga      360

ucaacgacgg agacaagccc aaggugcagg ucagcuacaa gggggagacc aaggcauucu      420

accccgagga gaucucgucc auggugcuga ccaagaugaa ggagaucgcc gaggcguacc      480

ugggcuaccc ggugaccaac gcggugauca ccgugccggc cuacuucaac gacucgcagc      540

gccaggccac caaggaugcg ggugugaucg cggggcucaa cgugcugcgg aucaucaacg      600

agcccacggc cgccgccauc gccuacggcc uggacagaac gggcaagggg gagcgcaacg      660

ugcucaucuu ugaccugggc gggggcaccu ucgacguguc cauccugacg aucgacgacg      720

gcaucuucga ggugaaggcc acggccgggg acacccaccu ggguggggag gacuuugaca      780

acaggcuggu gaaccacuuc guggaggagu ucaagagaaa acacaagaag gacaucagcc      840

agaacaagcg agccgugagg cggcugcgca ccgccugcga gagggccaag aggacccugu      900

cguccagcac ccaggccagc cuggagaucg acucccuguu ugagggcauc gacuucuaca      960

cguccaucac cagggcgagg uucgaggagc ugugcuccga ccuguuccga agcacccugg     1020

agcccgugga gaaggcucug cgcgacgcca agcuggacaa ggcccagauu cacgaccugg     1080

uccuggucgg gggcuccacc cgcaucccca aggugcagaa gcugcugcag gacuucuuca     1140

acgggcgcga ccugaacaag agcaucaacc ccgacgaggc uguggccuac ggggcggcgg     1200

ugcaggcggc cauccugaug ggggacaagu ccgagaacgu gcaggaccug cugcugcugg     1260

acguggcucc ccugucgcug gggcuggaga cggccggagg cgugaugacu gcccugauca     1320

agcgcaacuc caccaucccc accaagcaga cgcagaucuu caccaccuac uccgacaacc     1380

aacccggggu gcugauccag guguacgagg gcgagagggc caugacgaaa gacaacaauc     1440

uguuggggcg cuucgagcug agcggcaucc cuccggcccc caggggcgug ccccagaucg     1500

aggugaccuu cgacaucgau gccaacggca uccugaacgu cacggccacg gacaagagca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg ccgccugagc aaggaggaga     1620

ucgagcgcau ggugcaggag gcggagaagu acaaagcgga ggacgaggug cagcgcgaga     1680

gggugucagc caagaacgcc cuggaguccu acgccuucaa caugaaaagc gccguggagg     1740

augaggggcu caagggcaag aucagcgagg cggacaagaa gaagguucug gacaaguguc     1800

aagaggucau cucguggcug gacgccaaca ccuuggccga gaaggacgag uuugagcaca     1860

agaggaagga gcuggagcag gucuguaacc ccaucaucag cggacuguac cagggugccg     1920

guggucccgg gccuggcggc uucggggcuc agggucccaa gggagggucu gggucaggcc     1980

cuaccauuga ggagguggau uagggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  6131
<211>  2273
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (wt)

<400>  6131
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuacugcca agggaaucgc cauaggcauc gaccugggca      120

ccaccuacuc cugugugggg guguuccagc acggcaaggu ggagaucauc gccaacgacc      180

agggcaaccg caccaccccc agcuacgugg ccuucacaga caccgagcgg cucauugggg      240

augcggccaa gaaccaggua gcaaugaauc cccagaacac uguuuuugau gcuaaacguc      300

ugaucggcag gaaauuuaau gauccuguug uacaagcaga uaugaaacuu uggccuuuuc      360

aagugauuaa ugaaggaggc aagcccaaag uccuuguguc cuacaaaggg gagaauaaag      420

cauucuaccc ugaggaaauc ucuucgaugg uauugacuaa guugaaggag acugcugagg      480

ccuuuuuggg ccacccuguc accaaugcag ugauuaccgu gccagccuau uucaaugacu      540

cucaacguca ggcuacuaag gaugcaggag ugauugcugg acuuaaugug cuaagaauca      600

ucaaugagcc cacggcugcu gccauugccu augguuuaga uaaaggaggu caaggagaac      660

gacauguccu gauuuuugau cuggguggag gcacauuuga ugugucaauu cugaccauag      720

augaugggau uuuugaggua aaggccacug cuggggacac ucaccugggu ggggaggacu      780

uugacaacag gcuugugagc cacuucgugg aggaguucaa gaggaaacac aaaaaggaca      840

ucagccagaa caagcgagcc gugaggcggc ugcgcaccgc cugcgagagg gccaagagga      900

cccugucguc cagcacccag gccaaccuag aaauugauuc acuuuaugaa ggcauugacu      960

ucuauacauc caucaccaga gcucgauuug aagaguugug ugcagaccug uuuaggggua     1020

cccuggagcc uguagaaaaa gcgcuucggg augccaagau ggauaaggcu aaaauccaug     1080

acauuguuuu aguagggggc uccacccgca uccccaaggu gcagcggcug cuucaggacu     1140

acuucaaugg acgugaucuc aacaagagca ucaacccuga ugaggccgua gcauaugggg     1200

cugcgguaca agcagccauc cugauggggg acaagucuga gaagguacag gaccugcugc     1260

ugcuggacgu ggcuccccug ucccuggggc uggagacggc ugggggcgug augacugccc     1320

ugauaaagcg caacuccacc auccccacca agcagacaca gauuuucacc accuacucug     1380

acaaccaacc cggggugcug auccaggugu augagggcga gagggccaug acaaaggaca     1440

acaaccugcu ggggcgguuu gaccugacug gaaucccucc agcacccagg ggaguuccuc     1500

agaucgaggu gacguuugac auugaugcca augguauucu caaugucaca gccacggaca     1560

agagcaccgg caaggugaac aagaucacca ucaccaauga caagggccgc cugagcaagg     1620

aggagauuga gcgcaugguu cuggaugcug agaaauauaa agcugaagau gagguccaga     1680

gggagaaaau ugcugcaaag aaugccuuag aauccuaugc uuuuaacaug aagaguguug     1740

ugagugauga agguuugaag ggcaagauua gugagucuga uaaaaauaaa auauuggaua     1800

aaugcaacga gcuccuuucg uggcuggagg ucaaucaacu ggcagagaaa gaugaguuug     1860

aucauaagag aaaggaauug gagcagaugu guaacccuau caucacaaaa cucuaccaag     1920

gaggaugcac ugggccugcc ugcggaacag gguaugugcc uggaaggccu gccacaggcc     1980

ccacaauuga agaaguagau uaaggacuag ugcaucacau uuaaaagcau cucagccuac     2040

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     2100

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     2160

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            2273


<210>  6132
<211>  2870
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (wt)

<400>  6132
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucgguggugg gcauagaccu gggcuuccag agcugcuacg      120

ucgcuguggc ccgcgccggc ggcaucgaga cuaucgcuaa ugaguauagc gaccgcugca      180

cgccggcuug cauuucuuuu gguccuaaga aucguucaau uggagcagca gcuaaaagcc      240

agguaauuuc uaaugcaaag aacacagucc aaggauuuaa aagauuccau ggccgagcau      300

ucucugaucc auuuguggag gcagaaaaau cuaaccuugc auaugauauu gugcaguugc      360

cuacaggauu aacagguaua aaggugacau auauggagga agaacgaaau uuuaccacug      420

agcaagugac ugccaugcuu uuguccaaac ugaaggagac agccgaaagu guucuuaaga      480

agccuguagu ugacuguguu guuucgguuc cuuguuucua uacugaugca gaaagacgau      540

cagugaugga ugcaacacag auugcugguc uuaauugcuu gcgauuaaug aaugaaacca      600

cugcaguugc ucuugcauau ggaaucuaua agcaggaucu uccugccuua gaagagaaac      660

caagaaaugu aguuuuugua gacaugggcc acucugcuua ucaaguuucu guaugugcau      720

uuaauagagg aaaacugaaa guucuggcca cugcauuuga cacgacauug ggagguagaa      780

aauuugauga aguguuagua aaucacuucu gugaagaauu ugggaagaaa uacaagcuag      840

acauuaaguc caaaauccgu gcauuauuac gacucucuca ggagugugag aaacucaaga      900

aauugaugag ugcaaaugcu ucagaucucc cuuugagcau ugaauguuuu augaaugaug      960

uugauguauc uggaacuaug aauagaggca aauuucugga gaugugcaau gaucucuuag     1020

cuagagugga gccaccacuu cguaguguuu uggaacaaac caaguuaaag aaagaagaua     1080

uuuaugcagu ggagauaguu gguggugcua cacgaauccc ugcgguaaaa gagaagauca     1140

gcaaauuuuu cgguaaagaa cuuaguacaa cauuaaaugc ugaugaagcu gucacucgag     1200

gcugugcauu gcagugugcc aucuuaucgc cugcuuucaa agucagagaa uuuucuauca     1260

cugauguagu accauaucca auaucucuga gauggaacuc uccagcugaa gaagggucaa     1320

gugacuguga agucuuuucc aaaaaucaug cugcuccuuu cucuaaaguu cuuacauuuu     1380

auagaaagga accuuucacu cuugaggccu acuacagcuc uccucaggau uugcccuauc     1440

cagauccugc uauagcucag uuuucaguuc agaaagucac uccucagucu gauggcucca     1500

guucaaaagu gaaagucaaa guucgaguaa auguccaugg cauuuucagu guguccagug     1560

caucuuuagu ggagguucac aagucugagg aaaaugagga gccaauggaa acagaucaga     1620

augcaaagga ggaagagaag augcaagugg accaggagga accacauguu gaagaacaac     1680

agcagcagac accagcagaa aauaaggcag agucugaaga aauggagacc ucucaagcug     1740

gauccaagga uaaaaagaug gaccaaccac cccaagccaa gaaggcaaaa gugaagacca     1800

guacugugga ccugccaauc gagaaucagc uauuauggca gauagacaga gagaugcuca     1860

acuuguacau ugaaaaugag gguaagauga ucaugcagga uaaacuggag aaggagcgga     1920

augaugcuaa gaacgcagug gaggaauaug uguaugaaau gagagacaag cugaguggug     1980

aauaugagaa guuugugagu gaagaugauc guaacaguuu uacuuugaaa cuggaagaua     2040

cugaaaauug guuguaugag gauggagaag accagccaaa gcaaguuuau guugauaagu     2100

uggcugaauu aaaaaaucua ggucaaccua uuaagauacg uuuccaggaa ucugaagaac     2160

gaccaaaauu auuugaagaa cuagggaaac agauccaaca guauaugaaa auaaucagcu     2220

cuuucaaaaa caaggaggac caguaugauc auuuggaugc ugcugacaug acaaagguag     2280

aaaaaagcac aaaugaagca auggagugga ugaauaacaa gcuaaaucug cagaacaagc     2340

agaguuugac cauggaucca guugucaagu caaaagagau ugaagcuaaa auuaaggagc     2400

ugacaaguac uuguagcccu auaauuucaa agcccaaacc caaaguggaa ccuccaaaag     2460

aggaacaaaa aaaugcagag cagaauggac caguggaugg acaaggagac aacccaggcc     2520

cccaggcugc ugagcagggu acagacacag cugugccuuc ggauucagac aagaagcugc     2580

cugaaaugga cauugauuga ggacuagugc aucacauuua aaagcaucuc agccuaccau     2640

gagaauaaga gaaagaaaau gaagaucaau agcuuauuca ucucuuuuuc uuuuucguug     2700

guguaaagcc aacacccugu cuaaaaaaca uaaauuucuu uaaucauuuu gccucuuuuc     2760

ucugugcuuc aauuaauaaa aaauggaaag aaccuagauc uaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaagaauu                2870


<210>  6133
<211>  2867
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (wt)

<400>  6133
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucugugguug gcauugaccu cggcuuucuc aacugcuaca      120

uugcugucgc gagaaguggc ggcaucgaga ccaucgccaa ugaguacagc gacaggugua      180

ccccggccug uauaucauug ggaucaagaa cucgagccau uggaaaugca gcaaagagcc      240

agauagucac gaacguaaga aauacaauuc auggcuucaa aaagcugcau gggcgaucau      300

uugaugaucc cauugugcaa acugaaagga ucaggcuucc cuaugaacug cagaaaaugc      360

cuaauggaag ugcaggaguu aaggugcggu acuuagagga agagagaccu uuugcaauug      420

agcaaguuac uggaaugcug uuagccaagc ugaaagagac uucagaaaau gcuuugaaga      480

aaccaguggc ugacugugug auuucaauuc cuagcuuuuu uacugaugcc gagagaagau      540

cugugauggc ugcagcccag guugcaggcu uaaauuguuu aagguugaug aaugaaacua      600

cugcaguugc acuggcguau ggaauuuaua aacaggaucu ucccccauua gaugagaaac      660

caagaaaugu aguauuuauu gauaugggac auucugccua ucaggucuug guuugugcuu      720

uuaacaaagg aaaacuuaaa gucuuggcua cuaccuuuga uccauauuug gguggcagga      780

acuuugauga ggcuuuagua gacuacuucu gugaugaguu caagaccaaa uauaagauaa      840

augugaaaga aaacucucgg gccuuguugc guuuauauca ggaaugugaa aaacuaaaga      900

agcuaaugag ugcaaaugca ucagaucuuc cauugaacau ugaguguuuc augaaugacc      960

uugauguuuc uaguaaaaug aacagggcuc aauuugaaca acugugugcu ucccuuuugg     1020

ccaggguuga accaccuuua aaagcaguaa uggaacaagc uaacuuacaa cgugaagaca     1080

uuaguaguau agaaauugua ggaggagcaa cacgaauccc ugcagugaaa gaacaaauca     1140

cuaaauucuu ucuuaaagac auaaguacca cauuaaaugc ugaugaagcu guugcaagag     1200

gaugugcguu acagugugcg auucucucac cagcauuuaa agugcgugaa uuuuccauaa     1260

cagaccuugu ucccuauuca aucacauuaa gguggaagac cucuuuugaa gauggaagug     1320

gggaauguga aguuuucugu aagaaccauc cugccccauu cucaaaaguc auuacuuucc     1380

acaagaagga accauuugaa cuagaagcau uuuauacuaa uuuacaugaa gugccuuauc     1440

cugaugcaag aauugggagc uucacuauuc agaauguuuu uccacagucu gauggugaua     1500

guuccaaagu gaagguuaaa guucguguua acauccaugg aaucuucagu guggcuagcg     1560

caucaguaau ugagaagcaa aauuuggaag gcgaucacag ugaugcucca auggagacag     1620

aaacuucauu uaaaaaugaa aacaaagaua auauggauaa aaugcagguu gaucaagaag     1680

aagggcauca aaaaugucau gcugaacaca cuccagaaga ggaaauugau cauacaggag     1740

ccaaaacaaa gucagcuguc ucagacaaac aagaccgauu aaaucagaca cuuaaaaaag     1800

gaaaagucaa aaguauugau cuaccgaucc agaguagccu auguagacaa cuaggccaag     1860

aucuucucaa cagcuacauu gaaaaugagg ggaagaugau caugcaagau aaguuagaga     1920

aagaaagaaa ugaugcuaag aaugccguug aagaauaugu auaugauuuu agagacaggc     1980

ugggcacugu cuaugaaaaa uucaucacuc cagaagacuu gaguaaacug ucugcaguau     2040

uggaagacac agaaaauugg cuuuaugaag acggagagga ccaaccuaaa caaguuuaug     2100

uggauaagcu gcaagaacua aagaaauacg gccagccuau ucaaaugaag uacauggagc     2160

augaagagag accaaaagcc uuaaaugacu ugggaaaaaa gauccaacuu gucaugaaag     2220

ugauagaagc auauagaaac aaggaugaaa gauaugauca ucuggauccu acugaaaugg     2280

aaaagguuga aaaauguauc agugaugcca ugaguuggcu gaauaguaag augaaugcac     2340

agaacaaacu aagucucacu caagauccug ugguaaaagu uucagaaaua guagcaaagu     2400

caaaggaacu ggauaauuuc uguaacccca ucauuuacaa gcccaaacca aaagcagaag     2460

uuccugaaga caaaccaaaa gcuaauagug aacacaaugg cccaauggau ggacagagug     2520

gaacugaaac uaaaucagau ucaacaaaag acagcucaca gcauacuaaa uccucuggag     2580

agauggaagu ggacuaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2640

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2700

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2760

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2820

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2867


<210>  6134
<211>  2312
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (wt)

<400>  6134
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcucuccc ugguggccgc gaugcugcug cugcucagcg      120

cggcgcgggc cgaggaggag gacaagaagg aggacguggg cacggugguc ggcaucgacc      180

uggggaccac cuacuccugc gucggcgugu ucaagaacgg ccgcguggag aucaucgcca      240

acgaucaggg caaccgcauc acgccguccu augucgccuu cacuccugaa ggggaacguc      300

ugauuggcga ugccgccaag aaccagcuca ccuccaaccc cgagaacacg gucuuugacg      360

ccaagcggcu caucggccgc acguggaaug acccgucugu gcagcaggac aucaaguucu      420

ugccguucaa ggugguugaa aagaaaacua aaccauacau ucaaguugau auuggaggug      480

ggcaaacaaa gacauuugcu ccugaagaaa uuucugccau gguucucacu aaaaugaaag      540

aaaccgcuga ggcuuauuug ggaaagaagg uuacccaugc aguuguuacu guaccagccu      600

auuuuaauga ugcccaacgc caagcaacca aagacgcugg aacuauugcu ggccuaaaug      660

uuaugaggau caucaacgag ccuacggcag cugcuauugc uuauggccug gauaagaggg      720

agggggagaa gaacauccug guguuugacc uggguggcgg aaccuucgau gugucucuuc      780

ucaccauuga caaugguguc uucgaaguug uggccacuaa uggagauacu caucugggug      840

gagaagacuu ugaccagcgu gucauggaac acuucaucaa acuguacaaa aagaagacgg      900

gcaaagaugu caggaaagac aauagagcug ugcagaaacu ccggcgcgag guagaaaagg      960

ccaaacgggc ccugucuucu cagcaucaag caagaauuga aauugagucc uucuaugaag     1020

gagaagacuu uucugagacc cugacucggg ccaaauuuga agaacucaac auggaucugu     1080

uccggucuac uaugaagccc guccagaaag uguuggaaga uucugauuug aagaagucug     1140

auauugauga aauuguucuu guugguggcu cgacucgaau cccaaagauu cagcaacugg     1200

uuaaagaguu cuucaauggc aaggaaccau cccguggcau aaacccagau gaagcuguag     1260

cguauggugc ugcuguccag gcuggugugc ucucugguga ucaagauaca ggugaccugg     1320

uacugcuuga uguauguccc cuuacacuug guauugaaac ugugggaggu gucaugacca     1380

aacugauucc aaggaacaca guggugccua ccaagaaguc ucagaucuuu ucuacagcuu     1440

cugauaauca accaacuguu acaaucaagg ucuaugaagg ugaaagaccc cugacaaaag     1500

acaaucaucu ucuggguaca uuugaucuga cuggaauccc uccugcuccu cguggggucc     1560

cacagauuga agucaccuuu gagauagaug ugaaugguau ucuucgagug acagcugaag     1620

acaaggguac agggaacaaa aauaagauca caaucaccaa ugaccagaau cgccugacac     1680

cugaagaaau cgaaaggaug guuaaugaug cugagaaguu ugcugaggaa gacaaaaagc     1740

ucaaggagcg cauugauacu agaaaugagu uggaaagcua ugccuauucu cuaaagaauc     1800

agauuggaga uaaagaaaag cugggaggua aacuuuccuc ugaagauaag gagaccaugg     1860

aaaaagcugu agaagaaaag auugaauggc uggaaagcca ccaagaugcu gacauugaag     1920

acuucaaagc uaagaagaag gaacuggaag aaauuguuca accaauuauc agcaaacucu     1980

auggaagugc aggcccuccc ccaacuggug aagaggauac agcagaaaaa gaugaguugu     2040

agggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     2100

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     2160

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     2220

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   2312


<210>  6135
<211>  2279
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (wt)

<400>  6135
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccac gggagcucgc ggugggcauc gaccugggca      120

ccaccuacuc gugcgugggc guguuucagc agggccgcgu ggagauccug gccaacgacc      180

agggcaaccg caccacgccc agcuacgugg ccuucaccga caccgagcgg cuggucgggg      240

acgcggccaa gagccaggcg gcccugaacc cccacaacac cguguucgau gccaagcggc      300

ugaucgggcg caaguucgcg gacaccacgg ugcagucgga caugaagcac uggcccuucc      360

ggguggugag cgagggcggc aagcccaagg ugcgcguaug cuaccgcggg gaggacaaga      420

cguucuaccc cgaggagauc ucguccaugg ugcugagcaa gaugaaggag acggccgagg      480

cguaccuggg ccagcccgug aagcacgcag ugaucaccgu gcccgccuau uucaaugacu      540

cgcagcgcca ggccaccaag gacgcggggg ccaucgcggg gcucaacgug uugcggauca      600

ucaaugagcc cacggcagcu gccaucgccu augggcugga ccggcggggc gcgggagagc      660

gcaacgugcu cauuuuugac cugggugggg gcaccuucga ugugucgguu cucuccauug      720

acgcuggugu cuuugaggug aaagccacug cuggagauac ccaccuggga ggagaggacu      780

ucgacaaccg gcucgugaac cacuucaugg aagaguuccg gcggaagcau gggaaggacc      840

ugagcgggaa caagcgugcc cugcgcaggc ugcgcacagc cugugagcgc gccaagcgca      900

cccuguccuc cagcacccag gccacccugg agauagacuc ccuguucgag ggcguggacu      960

ucuacacguc caucacucgu gcccgcuuug aggaacugug cucagaccuc uuccgcagca     1020

cccuggagcc gguggagaag gcccugcggg augccaagcu ggacaaggcc cagauucaug     1080

acgucguccu gguggggggc uccacacgca uccccaaggu gcagaaguug cugcaggacu     1140

ucuucaacgg caaggagcug aacaagagca ucaacccuga ugaggcugug gccuaugggg     1200

cugcugugca ggcggccgug uugauggggg acaaauguga gaaagugcag gaucuccugc     1260

ugcuggaugu ggcuccccug ucucuggggc uggagacagc aggaggggug augaccacgc     1320

ugauccagag gaacgccacu auccccacca agcagaccca gacuuucacc accuacucgg     1380

acaaccagcc uggggucuuc auccaggugu augaggguga gagggccaug accaaggaca     1440

acaaccugcu ggggcguuuu gaacucagug gcaucccucc ugccccacgu ggaguccccc     1500

agauagaggu gacuuuugac auugaugcua auggcauccu gagcgugaca gccacugaca     1560

ggagcacagg uaaggcuaac aagaucacca ucaccaauga caagggccgg cugagcaagg     1620

aggaggugga gaggaugguu caugaagccg agcaguacaa ggcugaggau gaggcccaga     1680

gggacagagu ggcugccaaa aacucgcugg aggcccaugu cuuccaugug aaagguucuu     1740

ugcaagagga aagccuuagg gacaagauuc ccgaagagga caggcgcaaa augcaagaca     1800

agugucggga aguccuugcc uggcuggagc acaaccagcu ggcagagaag gaggaguaug     1860

agcaucagaa gagggagcug gagcaaaucu gucgccccau cuucuccagg cucuaugggg     1920

ggccuggugu cccugggggc agcaguugug gcacucaagc ccgccagggg gaccccagca     1980

ccggccccau cauugaggag guugauugag gacuagugca ucacauuuaa aagcaucuca     2040

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2100

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2160

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2279


<210>  6136
<211>  1451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (wt)

<400>  6136
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccac gggagcucgc ggugggcauc gaccugggca      120

ccaccuacuc gugcgugggc guguuucagc agggccgcgu ggagauccug gccaacgacc      180

agggcaaccg caccacgccc agcuacgugg ccuucaccga caccgagcgg cuggucgggg      240

acgcggccaa gagccaggcg gcccugaacc cccacaacac cguguucgau gccaagcggc      300

ugaucgggcg caaguucgcg gacaccacgg ugcagucgga caugaagcac uggcccuucc      360

agguggugag cgagggcggc aagcccaagg ugcgcguaug cuaccgcggg gaggacaaga      420

cguucuaccc cgaggagauc ucguccaugg ugcugagcaa gaugaaggag acggccgagg      480

cguaccuggg ccagcccgug aagcacgcag ugaucaccgu gcccaccuau uucaguaacu      540

cgcagcgcca ggccaccaag gacgcggggg ccaucgcggg gcucaaggug cugccgauca      600

ucaaugaggc cacggcagca gccaucgccu augggcugga ccggcggggc gcgggaaagc      660

gcaacgugcu cauuuuugac cugggugggg gcaccuucga ugugucgguu cucuccauug      720

acgccggugu cuuugaggug aaagccacug cuggagauac ccaccuggga ggagaggacu      780

ucgacaaccg gcucgugaac cacuucaugg aagaguuccg gcggaagcau gggaaggacc      840

ugagcgggaa caagcgugcc cugcgcaggc ugcgcacagc cugugagcgc gccaagcgca      900

ccccguccuc cagcacccag gccacccugg agauagacuc ccuguucgag ggcguggacu      960

ucuacaaguc caucacucgu gcccgcuuug aggaacugug cucagaccuc uuccgcagca     1020

cccuggagcc gguggagaag gcccugcggg augccaagcu ggacaaggcc cagauucaug     1080

acuucguccu ggggggaggg cuccacucgc auccccaagg ugcagaaguu gcugcaggac     1140

uucuucaacg gcaaggagcu gaacaagagc aucaacccug aggacuagug caucacauuu     1200

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1260

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1320

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1380

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaagaau u                                                          1451


<210>  6137
<211>  2288
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (wt)

<400>  6137
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccaagggac cugcaguugg uauugaucuu ggcaccaccu      120

acucuugugu ggguguuuuc cagcacggaa aagucgagau aauugccaau gaucagggaa      180

accgaaccac uccaagcuau gucgccuuua cggacacuga acgguugauc ggugaugccg      240

caaagaauca aguugcaaug aaccccacca acacaguuuu ugaugccaaa cgucugauug      300

gacgcagauu ugaugaugcu guuguccagu cugauaugaa acauuggccc uuuauggugg      360

ugaaugaugc uggcaggccc aagguccaag uagaauacaa gggagagacc aagagcuucu      420

auccagagga ggugucuucu augguucuga caaagaugaa ggaaauugca gaagccuacc      480

uugggaagac uguuaccaau gcugugguca cagugccagc uuacuuuaau gacucucagc      540

gucaggcuac caaagaugcu ggaacuauug cuggucucaa uguacuuaga auuauuaaug      600

agccaacugc ugcugcuauu gcuuacggcu uagacaaaaa gguuggagca gaaagaaacg      660

ugcucaucuu ugaccuggga gguggcacuu uugauguguc aauccucacu auugaggaug      720

gaaucuuuga ggucaagucu acagcuggag acacccacuu ggguggagaa gauuuugaca      780

accgaauggu caaccauuuu auugcugagu uuaagcgcaa gcauaagaag gacaucagug      840

agaacaagag agcuguaaga cgccuccgua cugcuuguga acgugcuaag cguacccucu      900

cuuccagcac ccaggccagu auugagaucg auucucucua ugaaggaauc gacuucuaua      960

ccuccauuac ccgugcccga uuugaagaac ugaaugcuga ccuguuccgu ggcacccugg     1020

acccaguaga gaaagcccuu cgagaugcca aacuagacaa gucacagauu caugauauug     1080

uccugguugg ugguucuacu cguaucccca agauucagaa gcugcuccaa gacuucuuca     1140

auggaaaaga acugaauaag agcaucaacc cugaugaagc uguugcuuau ggugcagcug     1200

uccaggcagc caucuugucu ggagacaagu cugagaaugu ucaagauuug cugcucuugg     1260

augucacucc ucuuucccuu gguauugaaa cugcuggugg agucaugacu guccucauca     1320

agcguaauac caccauuccu accaagcaga cacagaccuu cacuaccuau ucugacaacc     1380

agccuggugu gcuuauucag guuuaugaag gcgagcgugc caugacaaag gauaacaacc     1440

ugcuuggcaa guuugaacuc acaggcauac cuccugcacc ccgagguguu ccucagauug     1500

aagucacuuu ugacauugau gccaauggua uacucaaugu cucugcugug gacaagagua     1560

cgggaaaaga gaacaagauu acuaucacua augacaaggg ccguuugagc aaggaagaca     1620

uugaacguau gguccaggaa gcugagaagu acaaagcuga agaugagaag cagagggaca     1680

aggugucauc caagaacuca cuugaguccu augccuucaa caugaaagca acuguugaag     1740

augagaaacu ucaaggcaag auuaacgaug aggacaaaca gaagauucug gacaagugua     1800

augaaauuau caacuggcuu gauaagaauc agacugcuga gaaggaagaa uuugaacauc     1860

aacagaaaga gcuggagaaa guuugcaacc ccaucaucac caagcuguac cagagugcag     1920

gaggcaugcc aggaggaaug ccugggggau uuccuggugg uggagcuccu cccucuggug     1980

gugcuuccuc agggcccacc auugaagagg uugauuaagg acuagugcau cacauuuaaa     2040

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2100

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2160

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2280

aaagaauu                                                              2288


<210>  6138
<211>  2387
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (wt)

<400>  6138
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaagugcca gccgagcugc agcagcccgu cucgugggcg      120

ccgcagccuc ccggggcccu acggccgccc gccaccagga uagcuggaau ggccuuaguc      180

augaggcuuu uagacuuguu ucaaggcggg auuaugcauc agaagcaauc aagggagcag      240

uuguugguau ugauuugggu acuaccaacu ccugcguggc aguuauggaa gguaaacaag      300

caaaggugcu ggagaaugcc gaaggugcca gaaccacccc uucaguugug gccuuuacag      360

cagaugguga gcgacuuguu ggaaugccgg ccaagcgaca ggcugucacc aacccaaaca      420

auacauuuua ugcuaccaag cgucucauug gccggcgaua ugaugauccu gaaguacaga      480

aagacauuaa aaauguuccc uuuaaaauug uccgugccuc caauggugau gccuggguug      540

aggcucaugg gaaauuguau ucuccgaguc agauuggagc auuuguguug augaagauga      600

aagagacugc agaaaauuac uuggggcaca cagcaaaaaa ugcugugauc acagucccag      660

cuuauuucaa ugacucgcag agacaggcca cuaaagaugc uggccagaua ucuggacuga      720

augugcuucg ggugauuaau gagcccacag cugcugcucu ugccuauggu cuagacaaau      780

cagaagacaa agucauugcu guauaugauu uagguggugg aacuuuugau auuucuaucc      840

uggaaauuca gaaaggagua uuugagguga aauccacaaa uggggauacc uucuuaggug      900

gggaagacuu ugaccaggcc uugcuacggc acauugugaa ggaguucaag agagagacag      960

ggguugauuu gacuaaagac aacauggcac uucagagggu acgggaagcu gcugaaaagg     1020

cuaaauguga acucuccuca ucugugcaga cugacaucaa uuugcccuau cuuacaaugg     1080

auucuucugg acccaagcau uugaauauga aguugacccg ugcucaauuu gaagggauug     1140

ucacugaucu aaucagaagg acuaucgcuc caugccaaaa agcuaugcaa gaugcagaag     1200

ucagcaagag ugacauagga gaagugauuc uugugggugg caugacuagg augcccaagg     1260

uucagcagac uguacaggau cuuuuuggca gagccccaag uaaagcuguc aauccugaug     1320

aggcuguggc cauuggagcu gccauucagg gagguguguu ggccggcgau gucacggaug     1380

ugcugcuccu ugaugucacu ccccugucuc uggguauuga aacucuagga ggugucuuua     1440

ccaaacuuau uaauaggaau accacuauuc caaccaagaa aagccaggua uucucuacug     1500

ccgcugaugg ucaaacgcaa guggaaauua aaguguguca gggugaaaga gagauggcug     1560

gagacaacaa acuccuugga caguuuacuu ugauuggaau cccaccagcc ccucguggag     1620

uuccucagau ugaaguuaca uuugacauug augccaaugg gauaguacau guuucugcua     1680

aagauaaagg cacaggacgu gagcagcaga uuguaaucca gucuucuggu ggauuaagca     1740

aagaugauau ugaaaauaug guuaaaaaug cagagaaaua ugcugaagaa gaccggcgaa     1800

agaaggaacg aguugaagca guuaauaugg cugaaggaau cauucacgac acagaaacca     1860

agauggaaga guucaaggac caauuaccug cugaugagug caacaagcug aaagaagaga     1920

uuuccaaaau gagggagcuc cuggcuagaa aagacagcga aacaggagaa aauauuagac     1980

aggcagcauc cucucuucag caggcaucac ugaagcuguu cgaaauggca uacaaaaaga     2040

uggcaucuga gcgagaaggc ucuggaaguu cuggcacugg ggaacaaaag gaagaucaaa     2100

aggaggaaaa acaguaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     2160

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     2220

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     2280

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   2387


<210>  6139
<211>  2408
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (wt)

<400>  6139
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuggcugucc cggagauggg ccugcagggg cuguacaucg      120

gcuccagccc ggagcggucc ccagugccua gcccacccgg cuccccgagg acccaggaaa      180

gcugcggcau ugccccccuc acacccucgc agucuccaaa acccgagguc cgagcccccc      240

agcaggccuc cuucucugug gugguggcca uugacuucgg caccacgucu aguggcuaug      300

cuuucagcuu ugccagugac ccugaggcca uccacaugau gaggaaaugg gagggcggag      360

acccgggcgu ggcccaccag aagaccccga ccugccugcu gcugacuccg gagggcgccu      420

uccacagcuu uggcuacacc gcccgcgauu acuaccauga ccuggacccc gaagaggcgc      480

gggacuggcu cuacuucgag aaguucaaga ugaagaucca cagcgccacg gaucucaccu      540

ugaagaccca gcuagaggca guaaauggaa agacgaugcc cgcccuggag guguucgccc      600

augcccugcg cuucuucagg gagcacgccc uucaggagcu gagggagcag agcccaucgc      660

ugccagagaa ggacacugug cgcugggugu ugacggugcc ugccaucugg aaacagccag      720

ccaagcaguu caugcgggag gcugccuacc uggcuggacu ugugucccga gagaaugcag      780

agcagcuacu caucgcccug gagcccgagg ccgccucggu auacugccgc aagcugcgcc      840

ugcaccagcu ccuggaccug aguggccggg ccccaggugg ugggcgccug ggugagcgcc      900

gcuccaucga cuccagcuuc cgucaggcuc gggagcagcu gcgaaggucc cgccacagcc      960

gcacguuccu gguggaguca ggcguaggag agcugugggc agagaugcaa gcaggagacc     1020

gcuacguggu ggccgacugc ggcggaggca ccguggaccu gacggugcac cagcuggagc     1080

agccccaugg cacccucaag gagcucuaca aggcaucugg gggcccuuau ggcgcggugg     1140

gcguggaccu ggccuucgag cagcugcugu gccgcaucuu cggcgaggac uucaucgcca     1200

ccuucaaaag gcaacggccg gcagccuggg uagaucugac caucgccuuc gaggcucgca     1260

agcgcacugc uggcccacac cgugcagggg cgcucaacau cucgcugccc uucuccuuca     1320

uugacuucua ccgcaagcag cggggccaca acguggagac cgcucugcgc aggagcagcg     1380

ugaacuucgu gaaguggucc ucacagggga ugcuccgaau gucuugugaa gccaugaacg     1440

agcucuuuca gcccaccguc agcgggauca uccagcacau agaggcccug cuggcacggc     1500

cggaggugca gggugugaag cugcuguucc uagugggcgg cuucgccgag ucagcggugc     1560

ugcagcacgc ggugcaggcg gcgcugggcg cccgcggucu gcgugucgug gucccgcacg     1620

acgugggccu caccauccuc aaaggcgcgg ugcuguucgg ccaggcgccg ggcguggugc     1680

ggguccgccg cucgccgcuc accuauggcg ugggcgugcu caaccgcuuu gugccugggc     1740

gccacccgcc cgaaaagcug cugguucgcg acggccgccg cuggugcacc gacgucuucg     1800

agcgcuucgu ggccgccgag cagucggugg cccugggcga ggaggugcgg cgcagcuacu     1860

gcccggcgcg ucccggccag cggcgcguac ucaucaaccu guacugcugc gcggcagagg     1920

augcgcgcuu caucaccgac cccggcgugc gcaaaugcgg cgcgcucagc cucgagcuug     1980

agcccgccga cugcggccag gacaccgccg gcgcgccucc cggccgccgc gagauccgcg     2040

ccgccaugca guuuggcgac accgaaauua aggucaccgc cgucgacguc agcaccaauc     2100

gcuccgugcg cgcguccauc gacuuucuuu ccaacugagg acuagugcau cacauuuaaa     2160

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     2220

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     2280

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaagaauu                                                              2408


<210>  6140
<211>  1877
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (wt)

<400>  6140
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcggccaucg gaguucaccu gggcugcacc ucagccugug      120

uggccgucua uaaggauggc cgggcuggug ugguugcaaa ugaugccggu gaccgaguua      180

cuccagcugu uguugcuuac ucagaaaaug aagagauugu uggauuggca gcaaaacaaa      240

guagaauaag aaauauuuca aauacaguaa ugaaaguaaa gcagauccug ggcagaagcu      300

ccagugaucc acaagcucag aaauacaucg cggaaaguaa auguuuaguc auugaaaaaa      360

augggaaauu acgauaugaa auagauacug gagaagaaac aaaauuuguu aacccagaag      420

auguugccag acugauauuu aguaaaauga aagaaacggc acauucugua uugggcucag      480

augcaaauga uguaguuauu acugucccgu uugauuuugg agaaaagcaa aaaaaugcuc      540

uuggagaagc agcuagagcu gcuggauuua auguuuugcg auuaauucac gaaccgucug      600

cagcucugcu ugcuuaugga auuggacaag acuccccuac uggaaaaagc aauauuuugg      660

uguuuaagcu gggaggaaca uccuuaucuc ucagcgucau ggaaguuaac aguggaauau      720

aucggguucu uucaacaaac acugaugaua acaucggugg ugcacauuuc acagaaaccu      780

uagcacagua ucuagcuucu gaguuccaaa gauccuucaa acaugaugug agaggaaaug      840

cgcgagccau gaugaaauua acgaacagug cugaaguagc gaaacauucu uugucaaccu      900

ugggaagugc caacuguuuu cuugacucau uauaugaagg ucaagauuuu gauugcaaug      960

uguccagagc aagauuugaa cuucuuuguu cuccacuuuu uaauaagugu auagaagcaa     1020

ucagaggacu cuuagaucaa aauggauuua cagcagauga uaucaacaag guuguccuuu     1080

guggaggguc uucucgaauc ccaaagcuac agcaacugau uaaagaucuu uucccagcug     1140

uugagcuucu caauucuauc ccuccugaug aagugauccc uauuggugca gcuauagaag     1200

caggaauccu uauugggaaa gaaaaccugu ugguggaaga cucucuuaug auagaguguu     1260

cagccagaga uauuuuaguu aagggugugg acgaaucagg agccaguaga uucacagugc     1320

uguuuccauc agggacuccu uugccagcuc gaagacaaca cacauugcaa gccccuggaa     1380

gcauaucuuc agugugccuu gaacucuaug agucugaugg gaagaacucu gccaaagagg     1440

aaaccaaguu ugcacagguu guacuccagg auuuagauaa aaaagaaaau ggauuacgug     1500

auauauuagc uguucuuacu augaaaaggg auggaucuuu acaugugaca ugcacagauc     1560

aagaaacugg aaaaugugaa gcaaucucua uugagauagc aucuuaggga cuagugcauc     1620

acauuuaaaa gcaucucagc cuaccaugag aauaagagaa agaaaaugaa gaucaauagc     1680

uuauucaucu cuuuuucuuu uucguuggug uaaagccaac acccugucua aaaaacauaa     1740

auuucuuuaa ucauuuugcc ucuuuucucu gugcuucaau uaauaaaaaa uggaaagaac     1800

cuagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1860

aaaaaaaaaa aagaauu                                                    1877


<210>  6141
<211>  2924
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (wt)

<400>  6141
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucgguggugg gguuggacgu gggcucgcag agcugcuaca      120

ucgcgguagc ccgggccggg ggcaucgaga ccaucgccaa ugaguucagc gaccggugca      180

ccccgucagu cauaucauuu ggaucaaaaa auagaacaau cggaguugca gccaaaaauc      240

agcaaaucac ucaugcaaac aauacggugu cuaacuucaa aagauuucau ggccgagcau      300

ucaaugaccc cuucauucaa aaggagaagg aaaacuugag uuacgauuug guuccauuga      360

aaaauggugg aguuggaaua aagguaaugu acauggguga agaacaucua uuuagugugg      420

agcagauaac agccauguug uugacuaagc ugaaggaaac ugcugaaaac agccucaaga      480

aaccaguaac agauuguguu auuucagucc ccuccuucuu uacagaugcu gagaggcgau      540

cuguguuaga ugcugcacag auuguuggcc uaaacuguuu aagacuuaug aaugacauga      600

cagcuguugc uuugaauuac ggaauuuaua agcaggaucu cccaagccug gaugagaaac      660

cucggauagu gguuuuuguu gauaugggac auucagcuuu ucaagugucu gcuugugcuu      720

uuaacaaggg aaaauugaag guacugggaa cagcuuuuga uccuuucuua ggaggaaaaa      780

acuucgauga aaaguuagug gaacauuuuu gugcagaauu uaaaacuaag uacaaguugg      840

augcaaaauc caaaauacga gcacuccuac gucuguauca ggaaugugaa aaacugaaaa      900

agcuaaugag cucuaacagc acagaccuuc cacugaauau cgaaugcuuu augaaugaua      960

aagauguuuc cggaaagaug aacaggucac aauuugaaga acucugugcu gaacuucugc     1020

aaaagauaga aguaccccuu uauucacugu uggaacaaac ucaucucaaa guagaagaug     1080

ugagugcagu ugagauuguu ggaggcgcua cacgaauccc agcugugaag gaaagaauug     1140

ccaaauucuu uggaaaagau auuagcacaa cacucaaugc agaugaagca guagccagag     1200

gaugugcauu acagugugca auacuuuccc cggcauuuaa aguuagagaa uuuuccguca     1260

cagaugcagu uccuuuucca auaucucuga ucuggaacca ugauucagaa gauacugaag     1320

guguucauga agucuuuagu cgaaaccaug cugcuccuuu cuccaaaguu cucaccuuuc     1380

ugagaagggg gccuuuugag cuagaagcau ucuauucuga uccccaagga guuccauauc     1440

cagaagcaaa aauaggccgc uuuguaguuc agaauguuuc ugcacagaaa gauggagaaa     1500

aaucuagagu aaaagucaaa gugcgaguca acacccaugg cauuuucacc aucucuacgg     1560

caucuauggu ggagaaaguc ccaacugagg agaaugaaau gucuucugaa gcugacaugg     1620

agugucugaa ucagagacca ccagaaaacc cagacacuga uaaaaauguc cagcaagaca     1680

acagugaagc uggaacacag ccccagguac aaacugaugc ucaacaaacc ucacagucuc     1740

ccccuucacc ugaacuuacc ucagaagaaa acaaaauccc agaugcugac aaagcaaaug     1800

aaaaaaaagu ugaccagccu ccagaagcua aaaagcccaa aauaaaggug gugaauguug     1860

agcugccuau ugaagccaac uuggucuggc aguuagggaa agaccuucuu aacauguaua     1920

uugagacaga ggguaagaug auaaugcaag auaaauugga aaaagaaagg aaugaugcua     1980

aaaaugcagu ugaggaauau guguaugagu ucagagacaa gcugugugga ccauaugaaa     2040

aauuuauaug ugagcaggau caucaaaauu uuuugagacu ccucacagaa acugaagacu     2100

ggcuguauga agaaggagag gaccaagcua aacaagcaua uguugacaag uuggaagaau     2160

uaaugaaaau uggcacucca guuaaaguuc gguuucagga agcugaagaa cggccaaaaa     2220

uguuugaaga acuaggacag aggcugcagc auuaugccaa gauagcagcu gacuucagaa     2280

auaaggauga gaaauacaac cauauugaug agucugaaau gaaaaaagug gagaagucug     2340

uuaaugaagu gauggaaugg augaauaaug ucaugaaugc ucaggcuaaa aagagucuug     2400

aucaggaucc aguuguacgu gcucaggaaa uuaaaacaaa aaucaaggaa uugaacaaca     2460

caugugaacc cguuguaaca caaccgaaac caaaaauuga aucacccaaa cuggaaagaa     2520

cuccaaaugg cccaaauauu gauaaaaagg aagaagauuu agaagacaaa aacaauuuug     2580

gugcugaacc uccacaucag aauggugaau guuacccuaa ugagaaaaau ucuguuaaua     2640

uggacuugga cuagggacua gugcaucaca uuuaaaagca ucucagccua ccaugagaau     2700

aagagaaaga aaaugaagau caauagcuua uucaucucuu uuucuuuuuc guugguguaa     2760

agccaacacc cugucuaaaa aacauaaauu ucuuuaauca uuuugccucu uuucucugug     2820

cuucaauuaa uaaaaaaugg aaagaaccua gaucuaaaaa aaaaaaaaaa aaaaaaaaaa     2880

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaag aauu                      2924


<210>  6142
<211>  3347
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (wt)

<400>  6142
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagacaaag uuaggaggca gaggccgagg aggcgagucu      120

guugggccuu gguggcugug cucuuggcag accuguuggc acugagugau acacuggcag      180

ugaugucugu ggaccugggc agugagucca ugaagguggc cauugucaaa ccuggagugc      240

ccauggaaau ugucuugaau aaggaaucuc ggaggaaaac accggugauc gugacccuga      300

aagaaaauga aagauucuuu ggagacagug cagcaagcau ggcgauuaag aauccaaagg      360

cuacgcuacg uuacuuccag caccuccugg ggaagcaggc agauaacccc cauguagcuc      420

uuuaccaggc ccgcuucccg gagcacgagc ugacuuucga cccacagagg cagacugugc      480

acuuucagau cagcucgcag cugcaguucu caccugagga aguguugggc augguucuca      540

auuauucucg uucucuagcu gaagauuuug cagagcagcc caucaaggau gcagugauca      600

ccgugccagu cuucuucaac caggccgagc gccgagcugu gcugcaggcu gcucguaugg      660

cuggccucaa agugcugcag cucaucaaug acaacaccgc cacugcccuc agcuauggug      720

ucuuccgccg gaaagauauu aacaccacug cccagaauau cauguucuau gacaugggcu      780

caggcagcac cguaugcacc auugugaccu accagauggu gaagacuaag gaagcuggga      840

ugcagccaca gcugcagauc cggggaguag gauuugaccg uacccugggg ggccuggaga      900

uggagcuccg gcuucgagaa cgccuggcug ggcuuuucaa ugagcagcgc aagggucaga      960

gagcaaagga ugugcgggag aacccgcgug ccauggccaa gcugcugcgu gaggcuaauc     1020

ggcucaaaac cguccucagu gccaacgcug accacauggc acagauugaa ggccugaugg     1080

augaugugga cuucaaggca aaagugacuc guguggaauu ugaggaguug ugugcagacu     1140

uguuugagcg ggugccuggg ccuguacagc aggcccucca gagugccgaa augagucugg     1200

augagauuga gcaggucauc cuggugggug gggccacucg gguccccaga guucaggagg     1260

ugcugcugaa ggccgugggc aaggaggagc uggggaagaa caucaaugca gaugaagcag     1320

ccgccauggg ggcaguguac caggcagcug cgcucagcaa agccuuuaaa gugaagccau     1380

uugucguccg agaugcagug gucuacccca uccuggugga guucacgagg gagguggagg     1440

aggagccugg gauucacagc cugaagcaca auaaacgggu acucuucucu cggauggggc     1500

ccuacccuca acgcaaaguc aucaccuuua accgcuacag ccaugauuuc aacuuccaca     1560

ucaacuacgg cgaccugggc uuccuggggc cugaagaucu ucggguauuu ggcucccaga     1620

aucugaccac agugaagcua aaaggggugg gugacagcuu caagaaguau ccugacuacg     1680

aguccaaggg caucaaggcu cacuucaacc uggaugagag uggcgugcuc agucuagaca     1740

ggguggaguc uguauuugag acacugguag aggacagcgc agaagaggaa ucuacucuca     1800

ccaaacuugg caacaccauu uccagccugu uuggaggcgg uaccacacca gaugccaagg     1860

agaaugguac ugauacuguc caggaggaag aggagagccc ugcagagggg agcaaggacg     1920

agccugggga gcaggucgag cucaaggagg aagcugaggc cccaguggag gauggcucuc     1980

agcccccacc cccugaaccu aagggagaug caaccccuga gggagaaaag gccacagaaa     2040

aagaaaaugg ggacaagucu gaggcccaga aaccaaguga gaaggcagag gcagggccug     2100

agggcgucgc uccagcccca gagggagaga agaagcagaa gcccgccagg aagcggcgaa     2160

ugguagagga gaucggggug gagcugguug uucuggaccu gccugacuug ccagaggaua     2220

agcuggcuca gucggugcag aaacuucagg acuugacacu ccgagaccug gagaagcagg     2280

aacgggaaaa agcugccaac agcuuggaag cauucauauu ugagacccag gacaagcugu     2340

accagcccga guaccaggaa guguccacag aggagcagcg ugaggagauc ucugggaagc     2400

ucagcgccgc auccaccugg cuggaggaug aggguguugg agccaccaca gugauguuga     2460

aggagaagcu ggcugagcug aggaagcugu gccaagggcu guuuuuucgg guagaggagc     2520

gcaagaagug gcccgaacgg cugucugccc ucgauaaucu ccucaaccau uccagcaugu     2580

uccucaaggg ggcccggcuc aucccagaga uggaccagau cuucacugag guggagauga     2640

caacguuaga gaaagucauc aaugagaccu gggccuggaa gaaugcaacu cuggccgagc     2700

aggcuaagcu gcccgccaca gagaagccug uguugcucuc aaaagacauu gaagcuaaga     2760

ugauggcccu ggaccgagag gugcaguauc ugcucaauaa ggccaaguuu accaagcccc     2820

ggccccggcc uaaggacaag aaugggaccc gggcagagcc accccucaau gccagugcca     2880

gugaccaggg ggagaagguc aucccuccag caggccagac ugaagaugca gagcccauuu     2940

cagaaccuga gaaaguagag acuggauccg agccaggaga cacugagccu uuggaguuag     3000

gagguccugg agcagaaccu gaacagaaag aacaaucgac aggacagaag cggccuuuga     3060

agaacgacga acuauaagga cuagugcauc acauuuaaaa gcaucucagc cuaccaugag     3120

aauaagagaa agaaaaugaa gaucaauagc uuauucaucu cuuuuucuuu uucguuggug     3180

uaaagccaac acccugucua aaaaacauaa auuucuuuaa ucauuuugcc ucuuuucucu     3240

gugcuucaau uaauaaaaaa uggaaagaac cuagaucuaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aagaauu                   3347


<210>  6143
<211>  2546
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (wt)

<400>  6143
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccugaggaaa cccagaccca agaccaaccg auggaggagg      120

aggagguuga gacguucgcc uuucaggcag aaauugccca guugauguca uugaucauca      180

auacuuucua cucgaacaaa gagaucuuuc ugagagagcu cauuucaaau ucaucagaug      240

cauuggacaa aauccgguau gagagcuuga cagaucccag uaaauuagac ucugggaaag      300

agcugcauau uaaccuuaua ccgaacaaac aagaucgaac ucucacuauu guggauacug      360

gaauuggaau gaccaaggcu gacuugauca auaaccuugg uacuaucgcc aagucuggga      420

ccaaagcguu cauggaagca uugcaggcug gugcagauau cucuaugauu ggccaguucg      480

guguugguuu uuauucugcu uauuugguug cugagaaagu aacugugauc accaaacaua      540

acgaugauga gcaguacgcu ugggaguccu cagcaggggg aucauucaca gugaggacag      600

acacagguga accuaugggu cguggaacaa aaguuauccu acaccugaaa gaagaccaaa      660

cugaguacuu ggaggaacga agaauaaagg agauugugaa gaaacauucu caguuuauug      720

gauaucccau uacucuuuuu guggagaagg aacgugauaa agaaguaagc gaugaugagg      780

cugaagaaaa ggaagacaaa gaagaagaaa aagaaaaaga agagaaagag ucggaagaca      840

aaccugaaau ugaagauguu gguucugaug aggaagaaga aaagaaggau ggugacaaga      900

agaagaagaa gaagauuaag gaaaaguaca ucgaucaaga agaacucaac aaaacaaagc      960

ccaucuggac cagaaauccc gacgauauua cuaaugagga guacggagag uucuauaaga     1020

gcuugaccaa ugacugggaa gaucacuugg cagugaagca uuuuucaguu gaaggacagu     1080

uggaguucag agcccuucua uuugucccac gacgugcucc uuuugaucug uuugaaaaca     1140

gaaagaaaaa gaacaacauc aaauuguaug uacgcagagu uuucaucaug gauaacugug     1200

aggagcuaau cccugaauau cugaacuuca uuagaggggu gguagacucg gaggaucucc     1260

cucuaaacau aucccgugag auguugcaac aaagcaaaau uuugaaaguu aucaggaaga     1320

auuuggucaa aaaaugcuua gaacucuuua cugaacuggc ggaagauaaa gagaacuaca     1380

agaaauucua ugagcaguuc ucuaaaaaca uaaagcucgg aauacacgaa gacucucaaa     1440

aucggaagaa gcucucagag cuguuaaggu acuacacauc ugccucuggu gaugagaugg     1500

uuucucucaa ggacuacugc accagaauga aggagaacca gaaacauauc uauuauauca     1560

caggugagac caaggaccag guagcuaacu cagccuuugu ggaacgucuu cggaaacaug     1620

gcuuagaagu gaucuauaug auugagccca uugaugagua cuguguccaa cagcugaagg     1680

aauuugaggg gaagacuuua gugucaguca ccaaagaagg ccuggaacuu ccagaggaug     1740

aagaagagaa aaagaagcag gaagagaaaa aaacaaaguu ugagaaccuc ugcaaaauca     1800

ugaaagacau auuggagaaa aaaguugaaa aggugguugu gucaaaccga uuggugacau     1860

cuccaugcug uauugucaca agcacauaug gcuggacagc aaacauggag agaaucauga     1920

aagcucaagc ccuaagagac aacucaacaa uggguuacau ggcagcaaag aaacaccugg     1980

agauaaaccc ugaccauucc auuauugaga ccuuaaggca aaaggcagag gcugauaaga     2040

acgacaaguc ugugaaggau cuggucaucu ugcuuuauga aacugcgcuc cugucuucug     2100

gcuucagucu ggaagauccc cagacacaug cuaacaggau cuacaggaug aucaaacuug     2160

gucuggguau ugaugaagau gacccuacug cugaugauac cagugcugcu guaacugaag     2220

aaaugccacc ccuugaagga gaugacgaca caucacgcau ggaagaagua gacuaaggac     2280

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     2340

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     2400

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     2460

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2520

aaaaaaaaaa aaaaaaaaaa agaauu                                          2546


<210>  6144
<211>  686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (wt)

<400>  6144
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gauuccagua aauuagacuc ugggaaaggg cugcauauua      120

accuuguacc aaacaaacaa aaucaaaccc ucacuauugu ggacacuaga auuggaauga      180

ccaagacuga cuugaucaau aaccucggua cugucaccaa gucugggacc aaagcauuca      240

uggaagcauu gcaggcugau gcagauaucu cuaugauugg ccauuucggg guugguuuuu      300

auucugcuua uuugguugcc aagaaaguaa cugugaucag caaacauaac aaugaugagc      360

aguacaccug ggaguccuca gcagggggau cauucacagu gaggacagac gagugaggac      420

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      480

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      540

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      600

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa agaauu                                           686


<210>  6145
<211>  2522
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (wt)

<400>  6145
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccugaggaag ugcaccaugg agaggaggag guggagacuu      120

uugccuuuca ggcagaaauu gcccaacuca ugucccucau caucaauacc uucuauucca      180

acaaggagau uuuccuucgg gaguugaucu cuaaugcuuc ugaugccuug gacaagauuc      240

gcuaugagag ccugacagac ccuucgaagu uggacagugg uaaagagcug aaaauugaca      300

ucauccccaa cccucaggaa cguacccuga cuuugguaga cacaggcauu ggcaugacca      360

aagcugaucu cauaaauaau uugggaacca uugccaaguc ugguacuaaa gcauucaugg      420

aggcucugca ggcuggugca gacaucucca ugauugggca guuugguguu ggcuuuuauu      480

cugccuacuu gguggcagag aaagugguug ugaucacaaa gcacaacgau gaugaacagu      540

augcuuggga gucuucugcu ggagguuccu ucacugugcg ugcugaccau ggugagccca      600

uuggcagggg uaccaaagug auccuccauc uuaaagaaga ucagacagag uaccuagaag      660

agaggcgggu caaagaagua gugaagaagc auucucaguu cauaggcuau cccaucaccc      720

uuuauuugga gaaggaacga gagaaggaaa uuagugauga ugaggcagag gaagagaaag      780

gugagaaaga agaggaagau aaagaugaug aagaaaaacc caagaucgaa gauguggguu      840

cagaugagga ggaugacagc gguaaggaua agaagaagaa aacuaagaag aucaaagaga      900

aauacauuga ucaggaagaa cuaaacaaga ccaagccuau uuggaccaga aacccugaug      960

acaucaccca agaggaguau ggagaguucu acaagagccu cacuaaugac ugggaagacc     1020

acuuggcagu caagcacuuu ucuguagaag gucaguugga guucagggca uugcuauuua     1080

uuccucgucg ggcucccuuu gaccuuuuug agaacaagaa gaaaaagaac aacaucaaac     1140

ucuauguccg ccguguguuc aucauggaca gcugugauga guugauacca gaguaucuca     1200

auuuuauccg uggugugguu gacucugagg aucugccccu gaacaucucc cgagaaaugc     1260

uccagcagag caaaaucuug aaagucauuc gcaaaaacau uguuaagaag ugccuugagc     1320

uguucucuga gcuggcagaa gacaaggaga auuacaagaa auucuaugag gcauucucua     1380

aaaaucucaa gcucggaauc cacgaagacu ccacuaaccg ccgccgccug ucugagcugc     1440

ugcgcuauca uaccucccag ucuggagaug agaugacauc ucugucagag uauguuucuc     1500

gcaugaagga gacacagaag uccaucuauu acaucacugg ugagagcaaa gagcaggucg     1560

ccaacucagc uuuuguggag cgagugcgga aacggggcuu cgagguggua uauaugaccg     1620

agcccauuga cgaguacugu gugcagcagc ucaaggaauu ugaugggaaa agccuggucu     1680

caguuaccaa ggagggucug gagcugccug aggaugagga ggagaagaag aagauggaag     1740

agagcaaggc aaaguuugag aaccucugca agcucaugaa agaaaucuua gauaagaagg     1800

uugagaaggu gacaaucucc aauagacuug ugucuucacc uugcugcauu gugaccagca     1860

ccuacggcug gacagccaau auggagcgga ucaugaaagc ccaggcacuu cgggacaacu     1920

ccaccauggg cuauaugaug gccaaaaagc accuggagau caacccugac caccccauug     1980

uggagacgcu gcggcagaag gcugaggccg acaagaauga uaaggcaguu aaggaccugg     2040

uggugcugcu guuugaaacc gcccugcuau cuucuggcuu uucccuugag gauccccaga     2100

cccacuccaa ccgcaucuau cgcaugauca agcuaggucu agguauugau gaagaugaag     2160

uggcagcaga ggaacccaau gcugcaguuc cugaugagau ccccccucuc gagggcgaug     2220

aggaugcguc ucgcauggaa gaagucgauu agggacuagu gcaucacauu uaaaagcauc     2280

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2340

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2400

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2460

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2520

uu                                                                    2522


<210>  6146
<211>  2759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (wt)

<400>  6146
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agggcccugu gggugcuggg ccucugcugc guccugcuga      120

ccuucggguc ggucagagcu gacgaugaag uugaugugga ugguacagua gaagaggauc      180

uggguaaaag uagagaagga ucaaggacgg augaugaagu aguacagaga gaggaagaag      240

cuauucaguu ggauggauua aaugcaucac aaauaagaga acuuagagag aagucggaaa      300

aguuugccuu ccaagccgaa guuaacagaa ugaugaaacu uaucaucaau ucauuguaua      360

aaaauaaaga gauuuuccug agagaacuga uuucaaaugc uucugaugcu uuagauaaga      420

uaaggcuaau aucacugacu gaugaaaaug cucuuucugg aaaugaggaa cuaacaguca      480

aaauuaagug ugauaaggag aagaaccugc ugcaugucac agacaccggu guaggaauga      540

ccagagaaga guugguuaaa aaccuuggua ccauagccaa aucugggaca agcgaguuuu      600

uaaacaaaau gacugaagca caggaagaug gccagucaac uucugaauug auuggccagu      660

uuggugucgg uuucuauucc gccuuccuug uagcagauaa gguuauuguc acuucaaaac      720

acaacaacga uacccagcac aucugggagu cugacuccaa ugaauuuucu guaauugcug      780

acccaagagg aaacacucua ggacggggaa cgacaauuac ccuugucuua aaagaagaag      840

caucugauua ccuugaauug gauacaauua aaaaucucgu caaaaaauau ucacaguuca      900

uaaacuuucc uauuuaugua uggagcagca agacugaaac uguugaggag cccauggagg      960

aagaagaagc agccaaagaa gagaaagaag aaucugauga ugaagcugca guagaggaag     1020

aagaagaaga aaagaaacca aagacuaaaa aaguugaaaa aacugucugg gacugggaac     1080

uuaugaauga uaucaaacca auauggcaga gaccaucaaa agaaguagaa gaagaugaau     1140

acaaagcauu cuacaaauca uuuucaaagg aaagugauga ccccauggcu uauauucacu     1200

uuacugcuga aggggaaguu accuucaaau caauuuuauu uguacccaca ucugcuccac     1260

guggucuguu ugacgaauau ggaucuaaaa agagcgauua cauuaagcuc uaugugcgcc     1320

guguauucau cacagacgac uuccaugaua ugaugccuaa auaccucaau uuugucaagg     1380

guguggugga cucagaugau cuccccuuga auguuucccg cgagacucuu cagcaacaua     1440

aacugcuuaa ggugauuagg aagaagcugg uucguaaaac gcuggacaug aucaagaaga     1500

uugcugauga uaaauacaau gauacuuuuu ggaaagaauu ugguaccaac aucaagcugg     1560

gugugauuga agaccacucg aaucgaacac gucuugcuaa acuucuuagg uuccagucuu     1620

cucaucaucc aacugacauu acuagccuag accaguaugu ggaaagaaug aaggaaaaac     1680

aagacaaaau cuacuucaug gcugggucca gcagaaaaga ggcugaaucu ucuccauuug     1740

uugagcgacu ucugaaaaag ggcuaugaag uuauuuaccu cacagaaccu guggaugaau     1800

acuguauuca ggcccuuccc gaauuugaug ggaagagguu ccagaauguu gccaaggaag     1860

gagugaaguu cgaugaaagu gagaaaacua aggagagucg ugaagcaguu gagaaagaau     1920

uugagccucu gcugaauugg augaaagaua aagcccuuaa ggacaagauu gaaaaggcug     1980

uggugucuca gcgccugaca gaaucuccgu gugcuuuggu ggccagccag uacggauggu     2040

cuggcaacau ggagagaauc augaaagcac aagcguacca aacgggcaag gacaucucua     2100

caaauuacua ugcgagucag aagaaaacau uugaaauuaa ucccagacac ccgcugauca     2160

gagacaugcu ucgacgaauu aaggaagaug aagaugauaa aacaguuuug gaucuugcug     2220

ugguuuuguu ugaaacagca acgcuucggu caggguaucu uuuaccagac acuaaagcau     2280

auggagauag aauagaaaga augcuucgcc ucaguuugaa cauugacccu gaugcaaagg     2340

uggaagaaga acccgaagaa gaaccugaag agacagcaga agacacaaca gaagacacag     2400

agcaagacga agaugaagaa auggaugugg gaacagauga agaagaagaa acagcaaagg     2460

aaucuacagc ugaaaaagau gaauuguaag gacuagugca ucacauuuaa aagcaucuca     2520

gccuaccaug agaauaagag aaagaaaaug aagaucaaua gcuuauucau cucuuuuucu     2580

uuuucguugg uguaaagcca acacccuguc uaaaaaacau aaauuucuuu aaucauuuug     2640

ccucuuuucu cugugcuuca auuaauaaaa aauggaaaga accuagaucu aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaagaauu      2759


<210>  6147
<211>  2462
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (wt)

<400>  6147
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgcgcgagc ugcgggcgcu gcugcugugg ggccgccgcc      120

ugcggccuuu gcugcgggcg ccggcgcugg cggccgugcc gggaggaaaa ccaauucugu      180

guccucggag gaccacagcc caguugggcc ccaggcgaaa cccagccugg agcuugcagg      240

caggacgacu guucagcacg cagaccgccg aggacaagga ggaaccccug cacucgauua      300

ucagcagcac agagagcgug caggguucca cuuccaaaca ugaguuccag gccgagacaa      360

agaagcuguu ggacauuguu gcccgguccc uguacucaga aaaagaggug uuuauacggg      420

agcugaucuc caaugccagc gaugccuugg aaaaacugcg ucacaaacug gugucugacg      480

gccaagcacu gccagaaaug gagauucacu ugcagaccaa ugccgagaaa ggcaccauca      540

ccauccagga uacugguauc gggaugacac aggaagaacu gguguccaac cuggggacga      600

uugccagauc ggggucaaag gccuuccugg augcucugca gaaccaggcu gaggccagca      660

gcaagaucau cggccaguuu ggaguggguu ucuacucagc uuucauggug gcugacagag      720

uggaggucua uucccgcucg gcagccccgg ggagccuggg uuaccagugg cuuucagaug      780

guucuggagu guuugaaauc gccgaagcau cgggaguuag aaccgggaca aaaaucauca      840

uccaccugaa auccgacugc aaggaguuuu ccagcgaggc ccgggugcga gaugugguaa      900

cgaaguacag caacuucguc agcuuccccu uguacuugaa uggaaggcgg augaacaccu      960

ugcaggccau cuggaugaug gaccccaagg auguccguga guggcaacau gaggaguucu     1020

accgcuacgu cgcgcaggcu cacgacaagc cccgcuacac ccugcacuau aagacggacg     1080

caccgcucaa cauccgcagc aucuucuacg ugcccgacau gaaaccgucc auguuugaug     1140

ugagccggga gcugggcucc agcguugcac uguacagccg caaaguccuc auccagacca     1200

aggccacgga cauccugccc aaguggcugc gcuucauccg agguguggug gacagugagg     1260

acauuccccu gaaccucagc cgggagcugc ugcaggagag cgcacucauc aggaaacucc     1320

gggacguuuu acagcagagg cugaucaaau ucuucauuga ccagaguaaa aaagaugcug     1380

agaaguaugc aaaguuuuuu gaagauuacg gccuguucau gcgggagggc auugugaccg     1440

ccaccgagca ggaggucaag gaggacauag caaagcugcu gcgcuacgag uccucggcgc     1500

ugcccuccgg gcagcuaacc agccucucag aauacgccag ccgcaugcgg gccggcaccc     1560

gcaacaucua cuaccugugc gcccccaacc gucaccuggc agagcacuca cccuacuaug     1620

aggccaugaa gaagaaagac acagagguuc ucuucugcuu ugagcaguuu gaugagcuca     1680

cccugcugca ccuucgugag uuugacaaga agaagcugau cucuguggag acggacauag     1740

ucguggauca cuacaaggag gagaaguuug aggacagguc cccagccgcc gagugccuau     1800

cagagaagga gacggaggag cucauggccu ggaugagaaa ugugcugggg ucgcguguca     1860

ccaacgugaa ggugacccuc cgacuggaca cccacccugc cauggucacc gugcuggaga     1920

ugggggcugc ccgccacuuc cugcgcaugc agcagcuggc caagacccag gaggagcgcg     1980

cacagcuccu gcagcccacg cuggagauca accccaggca cgcgcucauc aagaagcuga     2040

aucagcugcg cgcaagcgag ccuggccugg cucagcugcu gguggaucag auauacgaga     2100

acgccaugau ugcugcugga cuuguugacg acccuagggc cauggugggc cgcuugaaug     2160

agcugcuugu caaggcccug gagcgacacu gaggacuagu gcaucacauu uaaaagcauc     2220

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     2280

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     2340

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     2400

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     2460

uu                                                                    2462


<210>  6148
<211>  809
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (wt)

<400>  6148
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaauca gcagucuucc aacccaauua uuuaagugcu      120

gcuuuuguga uuucuugaag gugaagaugc acaccauguc cuccucgcau cucuucuacc      180

uggcgcugug ccugcucacc uucaccagcu cugccacggc uggaccggag acgcucugcg      240

gggcugagcu gguggaugcu cugcaguucg uguguggaga caggggcuuu uauuucaaca      300

agcccacagg guauggcucc agcagucgga gggcgccuca gacaggcauc guggaugagu      360

gcugcuuccg gagcugugau cuaaggaggc uggagaugua uugcgcaccc cucaagccug      420

ccaagucagc ucgcucuguc cgugcccagc gccacaccga caugcccaag acccagaagg      480

aaguacauuu gaagaacgca aguagaggga gugcaggaaa caagaacuac aggauguagg      540

gacuagugca ucacauuuaa aagcaucuca gccuaccaug agaauaagag aaagaaaaug      600

aagaucaaua gcuuauucau cucuuuuucu uuuucguugg uguaaagcca acacccuguc      660

uaaaaaacau aaauuucuuu aaucauuuug ccucuuuucu cugugcuuca auuaauaaaa      720

aauggaaaga accuagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaagaauu                                        809


<210>  6149
<211>  986
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (wt)

<400>  6149
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccacaagcgc cuucggucca guugccuucu      120

cccuggggcu gcuccuggug uugccugcug ccuucccugc cccaguaccc ccaggagaag      180

auuccaaaga uguagccgcc ccacacagac agccacucac cucuucagaa cgaauugaca      240

aacaaauucg guacauccuc gacggcaucu cagcccugag aaaggagaca uguaacaaga      300

guaacaugug ugaaagcagc aaagaggcac uggcagaaaa caaccugaac cuuccaaaga      360

uggcugaaaa agauggaugc uuccaaucug gauucaauga ggagacuugc cuggugaaaa      420

ucaucacugg ucuuuuggag uuugagguau accuagagua ccuccagaac agauuugaga      480

guagugagga acaagccaga gcugugcaga ugaguacaaa aguccugauc caguuccugc      540

agaaaaaggc aaagaaucua gaugcaauaa ccaccccuga cccaaccaca aaugccagcc      600

ugcugacgaa gcugcaggca cagaaccagu ggcugcagga caugacaacu caucucauuc      660

ugcgcagcuu uaaggaguuc cugcagucca gccugagggc ucugcggcaa auguagggac      720

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag      780

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa      840

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau      900

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      960

aaaaaaaaaa aaaaaaaaaa agaauu                                           986


<210>  6150
<211>  1628
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (wt)

<400>  6150
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccuugcuuu ggcugagagg auuucuguug gcaaguugcu      120

ggauuauagu gaggaguucc cccaccccag gauccgaggg gcacagcgcg gcccccgacu      180

guccguccug ugcgcuggcc gcccucccaa aggauguacc caacucucag ccagagaugg      240

uggaggccgu caagaagcac auuuuaaaca ugcugcacuu gaagaagaga cccgauguca      300

cccagccggu acccaaggcg gcgcuucuga acgcgaucag aaagcugcau gugggcaaag      360

ucggggagaa cggguaugug gagauagagg augacauugg aaggagggca gaaaugaaug      420

aacuuaugga gcagaccucg gagaucauca cguuugccga gucaggaaca gccaggaaga      480

cgcugcacuu cgagauuucc aaggaaggca gugaccuguc agugguggag cgugcagaag      540

ucuggcuguu ccuaaaaguc cccaaggcca acaggaccag gaccaaaguc accauccgcc      600

ucuuccagca gcagaagcac ccgcagggca gcuuggacac aggggaagag gccgaggaag      660

ugggcuuaaa gggggagagg agugaacugu ugcucucuga aaaaguagua gacgcucgga      720

aaagcaccug gcaugucuuc ccugucucca gcagcaucca gcgguugcug gaccagggca      780

agagcucccu ggacguucgg auugccugug agcagugcca ggagaguggc gccagcuugg      840

uucuccuggg caagaagaag aagaaagaag aggaggggga agggaaaaag aagggcggag      900

gugaaggugg ggcaggagca gaugaggaaa aggagcaguc gcacagaccu uuccucaugc      960

ugcaggcccg gcagucugaa gaccacccuc aucgccggcg ucggcggggc uuggagugug     1020

auggcaaggu caacaucugc uguaagaaac aguucuuugu caguuucaag gacaucggcu     1080

ggaaugacug gaucauugcu cccucuggcu aucaugccaa cuacugcgag ggugagugcc     1140

cgagccauau agcaggcacg uccggguccu cacuguccuu ccacucaaca gucaucaacc     1200

acuaccgcau gcggggccau agccccuuug ccaaccucaa aucgugcugu gugcccacca     1260

agcugagacc cauguccaug uuguacuaug augaugguca aaacaucauc aaaaaggaca     1320

uucagaacau gaucguggag gagugugggu gcucauaggg acuagugcau cacauuuaaa     1380

agcaucucag ccuaccauga gaauaagaga aagaaaauga agaucaauag cuuauucauc     1440

ucuuuuucuu uuucguuggu guaaagccaa cacccugucu aaaaaacaua aauuucuuua     1500

aucauuuugc cucuuuucuc ugugcuucaa uuaauaaaaa auggaaagaa ccuagaucua     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaagaauu                                                              1628


<210>  6151
<211>  3806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (wt)

<400>  6151
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucucagag uccuucuguu aacagccuug accuuauguc      120

auggguucaa cuuggacacu gaaaacgcaa ugaccuucca agagaacgca aggggcuucg      180

ggcagagcgu gguccagcuu cagggaucca gggugguggu uggagccccc caggagauag      240

uggcugccaa ccaaaggggc agccucuacc agugcgacua cagcacaggc ucaugcgagc      300

ccauccgccu gcaggucccc guggaggccg ugaacauguc ccugggccug ucccuggcag      360

ccaccaccag ccccccucag cugcuggccu guggucccac cgugcaccag acuugcagug      420

agaacacgua ugugaaaggg cucugcuucc uguuuggauc caaccuacgg cagcagcccc      480

agaaguuccc agaggcccuc cgaggguguc cucaagagga uagugacauu gccuucuuga      540

uugauggcuc ugguagcauc aucccacaug acuuucggcg gaugaaggag uuugucucaa      600

cugugaugga gcaauuaaaa aaguccaaaa ccuuguucuc uuugaugcag uacucugaag      660

aguuccggau ucacuuuacc uucaaagagu uccagaacaa cccuaaccca agaucacugg      720

ugaagccaau aacgcagcug cuugggcgga cacacacggc cacgggcauc cgcaaagugg      780

uacgagagcu guuuaacauc accaacggag cccgaaagaa ugccuuuaag auccuaguug      840

ucaucacgga uggagaaaag uuuggcgauc ccuugggaua ugaggauguc aucccugagg      900

cagacagaga gggagucauu cgcuacguca uugggguggg agaugccuuc cgcagugaga      960

aaucccgcca agagcuuaau accaucgcau ccaagccgcc ucgugaucac guguuccagg     1020

ugaauaacuu ugaggcucug aagaccauuc agaaccagcu ucgggagaag aucuuugcga     1080

ucgaggguac ucagacagga aguagcagcu ccuuugagca ugagaugucu caggaaggcu     1140

ucagcgcugc caucaccucu aauggccccu ugcugagcac uguggggagc uaugacuggg     1200

cugguggagu cuuucuauau acaucaaagg agaaaagcac cuucaucaac augaccagag     1260

uggauucaga caugaaugau gcuuacuugg guuaugcugc cgccaucauc uuacggaacc     1320

gggugcaaag ccugguucug ggggcaccuc gauaucagca caucggccug guagcgaugu     1380

ucaggcagaa cacuggcaug ugggagucca acgcuaaugu caagggcacc cagaucggcg     1440

ccuacuucgg ggccucccuc ugcuccgugg acguggacag caacggcagc accgaccugg     1500

uccucaucgg ggccccccau uacuacgagc agacccgagg gggccaggug uccgugugcc     1560

ccuugcccag ggggagggcu cgguggcagu gugaugcugu ucucuacggg gagcagggcc     1620

aacccugggg ccgcuuuggg gcagcccuaa cagugcuggg ggacguaaau ggggacaagc     1680

ugacggacgu ggccauuggg gccccaggag aggaggacaa ccggggugcu guuuaccugu     1740

uucacggaac cucaggaucu ggcaucagcc ccucccauag ccagcggaua gcaggcucca     1800

agcucucucc caggcuccag uauuuugguc agucacugag ugggggccag gaccucacaa     1860

uggauggacu gguagaccug acuguaggag cccaggggca cgugcugcug cucagguccc     1920

agccaguacu gagagucaag gcaaucaugg aguucaaucc cagggaagug gcaaggaaug     1980

uauuugagug uaaugaucag guggugaaag gcaaggaagc cggagagguc agagucugcc     2040

uccaugucca gaaaagcaca cgggaucggc uaagagaagg acagauccag aguguuguga     2100

cuuaugaccu ggcucuggac uccggccgcc cacauucccg cgccgucuuc aaugagacaa     2160

agaacagcac acgcagacag acacaggucu uggggcugac ccagacuugu gagacccuga     2220

aacuacaguu gccgaauugc aucgaggacc cagugagccc cauugugcug cgccugaacu     2280

ucucucuggu gggaacgcca uugucugcuu ucgggaaccu ccggccagug cuggcggagg     2340

augcucagag acucuucaca gccuuguuuc ccuuugagaa gaauuguggc aaugacaaca     2400

ucugccagga ugaccucagc aucaccuuca guuucaugag ccuggacugc cucguggugg     2460

gugggccccg ggaguucaac gugacaguga cugugagaaa ugauggugag gacuccuaca     2520

ggacacaggu caccuucuuc uucccgcuug accuguccua ccggaaggug uccacgcucc     2580

agaaccagcg cucacagcga uccuggcgcc uggccuguga gucugccucc uccaccgaag     2640

ugucuggggc cuugaaaagc accagcugca gcauaaacca ccccaucuuc ccggaaaacu     2700

cagaggucac cuuuaauauc acguuugaug uagacucuaa ggcuucccuu ggaaacaaac     2760

ugcuccucaa ggccaaugug accagugaga acaacaugcc cagaaccaac aaaaccgagu     2820

uccaacugga gcugccggug aaauaugcug ucuacauggu ggucaccagc cauggggucu     2880

ccacuaaaua ucucaacuuc acggccucag agaauaccag ucgggucaug cagcaucaau     2940

aucaggucag caaccugggg cagaggagcc uccccaucag ccugguguuc uuggugcccg     3000

uccggcugaa ccagacuguc auaugggacc gcccccaggu caccuucucc gagaaccucu     3060

cgaguacgug ccacaccaag gagcgcuugc ccucucacuc cgacuuucug gcugagcuuc     3120

ggaaggcccc cguggugaac ugcuccaucg cugucugcca gagaauccag ugugacaucc     3180

cguucuuugg cauccaggaa gaguucaaug cuacccucaa aggcaaccuc ucguuugacu     3240

gguacaucaa gaccucgcau aaccaccucc ugaucgugag cacagcugag aucuuguuua     3300

acgauuccgu guucacccug cugccgggac agggggcguu ugugaggucc cagacggaga     3360

ccaaagugga gccguucgag guccccaacc cccugccgcu caucgugggc agcucugucg     3420

ggggacugcu gcuccuggcc cucaucaccg ccgcgcugua caagcucggc uucuucaagc     3480

ggcaauacaa ggacaugaug agugaagggg gucccccggg ggccgaaccc caguagggac     3540

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     3600

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     3660

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     3720

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa agaauu                                          3806


<210>  6152
<211>  1751
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (wt)

<400>  6152
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucccuga agacgcuucc auuucugcuc uuacuccaug      120

ugcagauuuc caaggccuuu ccuguaucuu cuaaagagaa aaauacaaaa acuguucagg      180

acuaccugga aaaguucuac caauuaccaa gcaaccagua ucagucuaca aggaagaaug      240

gcacuaaugu gaucguugaa aagcugaaag aaaugcagcg auuuuuuggg uugaauguga      300

cggggaagcc aaaugaggaa acucuggaca ugaugaaaaa gccucgcugu ggagugccug      360

acaguggugg uuuuauguua accccaggaa accccaagug ggaacgcacu aacuugaccu      420

acaggauucg aaacuauacc ccacagcugu cagaggcuga gguagaaaga gcuaucaagg      480

augccuuuga acucuggagu guugcaucac cucucaucuu caccaggauc ucacagggag      540

aggcagauau caacauugcu uuuuaccaaa gagaucacgg ugacaauucu ccauuugaug      600

gacccaaugg aauccuugcu caugccuuuc agccaggcca agguauugga ggagaugcuc      660

auuuugaugc cgaagaaaca uggaccaaca ccuccgcaaa uuacaacuug uuucuuguug      720

cugcucauga auuuggccau ucuuuggggc ucgcucacuc cucugacccu ggugccuuga      780

uguaucccaa cuaugcuuuc agggaaacca gcaacuacuc acucccucaa gaugacaucg      840

auggcauuca ggccaucuau ggacuuucaa gcaacccuau ccaaccuacu ggaccaagca      900

cacccaaacc cugugacccc aguuugacau uugaugcuau caccacacuc cguggagaaa      960

uacuuuucuu uaaagacagg uacuucugga gaaggcaucc ucagcuacaa agagucgaaa     1020

ugaauuuuau uucucuauuc uggccauccc uuccaacugg uauacaggcu gcuuaugaag     1080

auuuugacag agaccucauu uuccuauuua aaggcaacca auacugggcu cugaguggcu     1140

augauauucu gcaagguuau cccaaggaua uaucaaacua uggcuucccc agcagcgucc     1200

aagcaauuga cgcagcuguu uucuacagaa guaaaacaua cuucuuugua aaugaccaau     1260

ucuggagaua ugauaaccaa agacaauuca uggagccagg uuaucccaaa agcauaucag     1320

gugccuuucc aggaauagag aguaaaguug augcaguuuu ccagcaagaa cauuucuucc     1380

augucuucag uggaccaaga uauuacgcau uugaucuuau ugcucagaga guuaccagag     1440

uugcaagagg caauaaaugg cuuaacugua gauauggcug aggacuagug caucacauuu     1500

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     1560

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     1620

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     1680

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaagaau u                                                          1751


<210>  6153
<211>  2471
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (wt)

<400>  6153
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccucuggc agccccuggu ccuggugcuc cuggugcugg      120

gcugcugcuu ugcugccccc agacagcgcc aguccacccu ugugcuguuc ccuggagacc      180

ugagaaccaa ucucaccgac aggcagcugg cagaggaaua ccuguaccgc uaugguuaca      240

cucggguggc agagaugcgu ggagagucga aaucucuggg gccugcgcug cugcuucucc      300

agaagcaacu gucccugccc gagaccggug agcuggauag cgccacgcug aaggccaugc      360

gaaccccacg gugcgggguc ccagaccugg gcagauucca aaccuuugag ggcgaccuca      420

aguggcacca ccacaacauc accuauugga uccaaaacua cucggaagac uugccgcggg      480

cggugauuga cgacgccuuu gcccgcgccu ucgcacugug gagcgcggug acgccgcuca      540

ccuucacucg cguguacagc cgggacgcag acaucgucau ccaguuuggu gucgcggagc      600

acggagacgg guaucccuuc gacgggaagg acgggcuccu ggcacacgcc uuuccuccug      660

gccccggcau ucagggagac gcccauuucg acgaugacga guuguggucc cugggcaagg      720

gcgucguggu uccaacucgg uuuggaaacg cagauggcgc ggccugccac uuccccuuca      780

ucuucgaggg ccgcuccuac ucugccugca ccaccgacgg ucgcuccgac ggcuugcccu      840

ggugcaguac cacggccaac uacgacaccg acgaccgguu uggcuucugc cccagcgaga      900

gacucuacac ccaggacggc aaugcugaug ggaaacccug ccaguuucca uucaucuucc      960

aaggccaauc cuacuccgcc ugcaccacgg acggucgcuc cgacggcuac cgcuggugcg     1020

ccaccaccgc caacuacgac cgggacaagc uguucggcuu cugcccgacc cgagcugacu     1080

cgacggugau ggggggcaac ucggcggggg agcugugcgu cuuccccuuc acuuuccugg     1140

guaaggagua cucgaccugu accagcgagg gccgcggaga ugggcgccuc uggugcgcua     1200

ccaccucgaa cuuugacagc gacaagaagu ggggcuucug cccggaccaa ggauacaguu     1260

uguuccucgu ggcggcgcau gaguucggcc acgcgcuggg cuuagaucau uccucagugc     1320

cggaggcgcu cauguacccu auguaccgcu ucacugaggg gccccccuug cauaaggacg     1380

acgugaaugg cauccggcac cucuaugguc cucgcccuga accugagcca cggccuccaa     1440

ccaccaccac accgcagccc acggcucccc cgacggucug ccccaccgga ccccccacug     1500

uccaccccuc agagcgcccc acagcuggcc ccacaggucc ccccucagcu ggccccacag     1560

guccccccac ugcuggcccu ucuacggcca cuacugugcc uuugaguccg guggacgaug     1620

ccugcaacgu gaacaucuuc gacgccaucg cggagauugg gaaccagcug uauuuguuca     1680

aggaugggaa guacuggcga uucucugagg gcagggggag ccggccgcag ggccccuucc     1740

uuaucgccga caaguggccc gcgcugcccc gcaagcugga cucggucuuu gaggagcggc     1800

ucuccaagaa gcuguucuuc uucucugggc gccaggugug gguguacaca ggcgcgucgg     1860

ugcugggccc gaggcgucug gacaagcugg gccugggagc cgacguggcc caggugaccg     1920

gggcccuccg gaguggcagg gggaagaugc ugcuguucag cgggcggcgc cucuggaggu     1980

ucgacgugaa ggcgcagaug guggaucccc ggagcgccag cgagguggac cggauguucc     2040

ccggggugcc uuuggacacg cacgacgucu uccaguaccg agagaaagcc uauuucugcc     2100

aggaccgcuu cuacuggcgc gugaguuccc ggagugaguu gaaccaggug gaccaagugg     2160

gcuacgugac cuaugacauc cugcagugcc cugaggacua gggacuagug caucacauuu     2220

aaaagcaucu cagccuacca ugagaauaag agaaagaaaa ugaagaucaa uagcuuauuc     2280

aucucuuuuu cuuuuucguu gguguaaagc caacacccug ucuaaaaaac auaaauuucu     2340

uuaaucauuu ugccucuuuu cucugugcuu caauuaauaa aaaauggaaa gaaccuagau     2400

cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2460

aaaaaagaau u                                                          2471


<210>  6154
<211>  1415
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (wt)

<400>  6154
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacuccaa acaccacaga ggacuaugac acgaccacag      120

aguuugacua uggggaugca acuccgugcc agaaggugaa cgagagggcc uuuggggccc      180

aacugcugcc cccucuguac uccuugguau uugucauugg ccugguugga aacauccugg      240

ugguccuggu ccuugugcaa uacaagaggc uaaaaaacau gaccagcauc uaccuccuga      300

accuggccau uucugaccug cuguuccugu ucacgcuucc cuucuggauc gacuacaagu      360

ugaaggauga cuggguuuuu ggugaugcca uguguaagau ccucucuggg uuuuauuaca      420

caggcuugua cagcgagauc uuuuucauca uccugcugac gauugacagg uaccuggcca      480

ucguccacgc cguguuugcc uugcgggcac ggaccgucac uuuugguguc aucaccagca      540

ucaucauuug ggcccuggcc aucuuggcuu ccaugccagg cuuauacuuu uccaagaccc      600

aaugggaguu cacucaccac accuguagcc uucacuuucc ucacgaaagc cuacgagagu      660

ggaagcuguu ucaggcucug aaacugaacc ucuuugggcu gguauugccu uuguugguca      720

ugaucaucug cuacacaggg auuauaaaga uucugcuaag acgaccaaau gagaagaaau      780

ccaaagcugu ccguuugauu uuugucauca ugaucaucuu uuuucucuuu uggacccccu      840

acaauuugac uauacuuauu ucuguuuucc aagacuuccu guucacccau gagugugagc      900

agagcagaca uuuggaccug gcugugcaag ugacggaggu gaucgccuac acgcacugcu      960

gugucaaccc agugaucuac gccuucguug gugagagguu ccggaaguac cugcggcagu     1020

uguuccacag gcguguggcu gugcaccugg uuaaauggcu ccccuuccuc uccguggaca     1080

ggcuggagag ggucagcucc acaucucccu ccacagggga gcaugaacuc ucugcugggu     1140

ucugaggacu agugcaucac auuuaaaagc aucucagccu accaugagaa uaagagaaag     1200

aaaaugaaga ucaauagcuu auucaucucu uuuucuuuuu cguuggugua aagccaacac     1260

ccugucuaaa aaacauaaau uucuuuaauc auuuugccuc uuuucucugu gcuucaauua     1320

auaaaaaaug gaaagaaccu agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa gaauu                                1415


<210>  6155
<211>  1073
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (wt)

<400>  6155
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaucgcugcu gggcgcuguu ccugucucuc ugcugcuacc      120

ugcgucuggu cagcgccgag ggggacccca uucccgagga gcuuuaugag augcugagug      180

accacucgau ccgcuccuuu gaugaucucc aacgccugcu gcacggagac cccggagagg      240

aagauggggc cgaguuggac cugaacauga cccgcuccca cucuggaggc gagcuggaga      300

gcuuggcucg uggaagaagg agccuggguu cccugaccau ugcugagccg gccaugaucg      360

ccgagugcaa gacgcgcacc gagguguucg agaucucccg gcgccucaua gaccgcacca      420

acgccaacuu ccuggugugg ccgcccugug uggaggugca gcgcugcucc ggcugcugca      480

acaaccgcaa cgugcagugc cgccccaccc aggugcagcu gcgaccuguc caggugagaa      540

agaucgagau ugugcggaag aagccaaucu uuaagaaggc cacggugacg cuggaagacc      600

accuggcaug caagugugag acaguggcag cugcacggcc ugugacccga agcccggggg      660

guucccagga gcagcgagcc aaaacgcccc aaacucgggu gaccauucgg acggugcgag      720

uccgccggcc ccccaagggc aagcaccgga aauucaagca cacgcaugac aagacggcac      780

ugaaggagac ccuuggagcc uagggacuag ugcaucacau uuaaaagcau cucagccuac      840

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg      900

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu      960

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1073


<210>  6156
<211>  1442
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (wt)

<400>  6156
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccggcuca ucuuugucua cacucuaauc ugcgcaaacu      120

uuugcagcug ucgggacacu ucugcaaccc cgcagagcgc auccaucaaa gcauugcgca      180

acgccaaccu caggcgagau gacuuguacc gaagagauga gaccauccag gugaaaggaa      240

acggcuacgu gcagaguccu agauucccga acagcuaccc caggaaccug cuccugacau      300

ggcggcuuca cucucaggag aauacacgga uacagcuagu guuugacaau caguuuggau      360

uagaggaagc agaaaaugau aucuguaggu augauuuugu ggaaguugaa gauauauccg      420

aaaccaguac cauuauuaga ggacgauggu guggacacaa ggaaguuccu ccaaggauaa      480

aaucaagaac gaaccaaauu aaaaucacau ucaaguccga ugacuacuuu guggcuaaac      540

cuggauucaa gauuuauuau ucuuugcugg aagauuucca acccgcagca gcuucagaga      600

ccaacuggga aucugucaca agcucuauuu cagggguauc cuauaacucu ccaucaguaa      660

cggaucccac ucugauugcg gaugcucugg acaaaaaaau ugcagaauuu gauacagugg      720

aagaucugcu caaguacuuc aauccagagu cauggcaaga agaucuugag aauauguauc      780

uggacacccc ucgguaucga ggcaggucau accaugaccg gaagucaaaa guugaccugg      840

auaggcucaa ugaugaugcc aagcguuaca guugcacucc caggaauuac ucggucaaua      900

uaagagaaga acugaaguug gccaaugugg ucuucuuucc acguugccuc cucgugcagc      960

gcuguggagg aaauuguggc uguggaacug ucaacuggag guccugcaca ugcaauucag     1020

ggaaaaccgu gaaaaaguau caugagguau uacaguuuga gccuggccac aucaagagga     1080

gggguagagc uaagaccaug gcucuaguug acauccaguu ggaucaccau gaacgaugug     1140

auuguaucug cagcucaaga ccaccucgau aaggacuagu gcaucacauu uaaaagcauc     1200

ucagccuacc augagaauaa gagaaagaaa augaagauca auagcuuauu caucucuuuu     1260

ucuuuuucgu ugguguaaag ccaacacccu gucuaaaaaa cauaaauuuc uuuaaucauu     1320

uugccucuuu ucucugugcu ucaauuaaua aaaaauggaa agaaccuaga ucuaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaagaa     1440

uu                                                                    1442


<210>  6157
<211>  1025
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (wt)

<400>  6157
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccaca gcaaguuucc cgccgccggg augagccgcc      120

cccuggacac cagccugcgc cucaagaccu ucagcuccaa gagcgaguac cagcuggugg      180

ugaacgcagu gcgcaagcug caggagagcg gcuucuacug gagcgcagug accggcggcg      240

aggcgaaccu gcugcucagu gccgagcccg ccggcaccuu ucugauccgc gacagcucgg      300

accagcgcca cuucuucacg cucagcguca agacccaguc ugggaccaag aaccugcgca      360

uccaguguga ggggggcagc uucucucugc agagcgaucc ccggagcacg cagcccgugc      420

cccgcuucga cugcgugcuc aagcuggugc accacuacau gccgcccccu ggagcccccu      480

ccuuccccuc gccaccuacu gaacccuccu ccgaggugcc cgagcagccg ucugcccagc      540

cacucccugg gagucccccc agaagggccu auuacaucua cuccgggggc gagaagaucc      600

cccugguguu gagccggccc cucuccucca acguggccac ucuucagcau cucugucgga      660

agaccgucaa cggccaccug gacuccuaug agaaagucac ccagcugccg gggcccauuc      720

gggaguuccu ggaccaguac gaugccccgc uuuaaggacu agugcaucac auuuaaaagc      780

aucucagccu accaugagaa uaagagaaag aaaaugaaga ucaauagcuu auucaucucu      840

uuuucuuuuu cguuggugua aagccaacac ccugucuaaa aaacauaaau uucuuuaauc      900

auuuugccuc uuuucucugu gcuucaauua auaaaaaaug gaaagaaccu agaucuaaaa      960

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

gaauu                                                                 1025


<210>  6158
<211>  1520
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (wt)

<400>  6158
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccgcccuccg ggcugcggcu gcugccgcug cugcuaccgc      120

ugcuguggcu acuggugcug acgccuggcc ggccggccgc gggacuaucc accuguaaga      180

cuaucgacau ggagcuggug aagcggaagc gcaucgaggc cauccgcggc cagauccugu      240

ccaagcugcg gcucgccagc cccccgagcc agggggaggu gccgcccggc ccgcugcccg      300

aggccgugcu cgcccuguac aacagcaccc gcgaccgggu ggccggggag agugcagaac      360

cggagcccga gccugaggcc gacuacuacg ccaaggaggu cacccgcgug cuaauggugg      420

aaacccacaa cgaaaucuau gacaaguuca agcagaguac acacagcaua uauauguucu      480

ucaacacauc agagcuccga gaagcgguac cugaacccgu guugcucucc cgggcagagc      540

ugcgucugcu gaggcucaag uuaaaagugg agcagcacgu ggagcuguac cagaaauaca      600

gcaacaauuc cuggcgauac cucagcaacc ggcugcuggc acccagcgac ucgccagagu      660

gguuaucuuu ugaugucacc ggaguugugc ggcagugguu gagccgugga ggggaaauug      720

agggcuuucg ccuuagcgcc cacugcuccu gugacagcag ggauaacaca cugcaagugg      780

acaucaacgg guucacuacc ggccgccgag gugaccuggc caccauucau ggcaugaacc      840

ggccuuuccu gcuucucaug gccaccccgc uggagagggc ccagcaucug caaagcuccc      900

ggcaccgccg agcccuggac accaacuauu gcuucagcuc cacggagaag aacugcugcg      960

ugcggcagcu guacauugac uuccgcaagg accucggcug gaaguggauc cacgagccca     1020

agggcuacca ugccaacuuc ugccucgggc ccugccccua cauuuggagc cuggacacgc     1080

aguacagcaa gguccuggcc cuguacaacc agcauaaccc gggcgccucg gcggcgccgu     1140

gcugcgugcc gcaggcgcug gagccgcugc ccaucgugua cuacgugggc cgcaagccca     1200

agguggagca gcuguccaac augaucgugc gcuccugcaa gugcagcuga ggacuagugc     1260

aucacauuua aaagcaucuc agccuaccau gagaauaaga gaaagaaaau gaagaucaau     1320

agcuuauuca ucucuuuuuc uuuuucguug guguaaagcc aacacccugu cuaaaaaaca     1380

uaaauuucuu uaaucauuuu gccucuuuuc ucugugcuuc aauuaauaaa aaauggaaag     1440

aaccuagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaaa aaaaagaauu                                                 1520


<210>  6159
<211>  1592
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (wt)

<400>  6159
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugug ugcugagcgc uuuucugauc cugcaucugg      120

ucacggucgc gcucagccug ucuaccugca gcacacucga uauggaccag uucaugcgca      180

agaggaucga ggcgauccgc gggcagaucc ugagcaagcu gaagcucacc agucccccag      240

aagacuaucc ugagcccgag gaaguccccc cggaggugau uuccaucuac aacagcacca      300

gggacuugcu ccaggagaag gcgagccgga gggcggccgc cugcgagcgc gagaggagcg      360

acgaagagua cuacgccaag gagguuuaca aaauagacau gccgcccuuc uuccccuccg      420

aaaaugccau cccgcccacu uucuacagac ccuacuucag aauuguucga uuugacgucu      480

cagcaaugga gaagaaugcu uccaauuugg ugaaagcaga guucagaguc uuucguuugc      540

agaacccaaa agccagagug ccugaacaac ggauugagcu auaucagauu cucaagucca      600

aagauuuaac aucuccaacc cagcgcuaca ucgacagcaa aguugugaaa acaagagcag      660

aaggcgaaug gcucuccuuc gauguaacug augcuguuca ugaauggcuu caccauaaag      720

acaggaaccu gggauuuaaa auuagcuuac acugucccug cugcacuuuu guaccaucua      780

auaauuacau caucccaaau aaaagugaag aacuagaagc aagauuugca gguauugaug      840

gcaccuccac auauaccagu ggugaucaga aaacuauaaa guccacuagg aaaaaaaaca      900

gugggaagac cccacaucuc cugcuaaugu uauugcccuc cuacagacuu gagucacaac      960

agaccaaccg gcggaagaag cgugcuuugg augcggccua uugcuuuaga aaugugcagg     1020

auaauugcug ccuacgucca cuuuacauug auuucaagag ggaucuaggg uggaaaugga     1080

uacacgaacc caaaggguac aaugccaacu ucugugcugg agcaugcccg uauuuaugga     1140

guucagacac ucagcacagc aggguccuga gcuuauauaa uaccauaaau ccagaagcau     1200

cugcuucucc uugcugcgug ucccaagauu uagaaccucu aaccauucuc uacuacauug     1260

gcaaaacacc caagauugaa cagcuuucua auaugauugu aaagucuugc aaaugcagcu     1320

aaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1380

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1440

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1500

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1592


<210>  6160
<211>  1586
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (wt)

<400>  6160
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacu ugcaaagggc ucuggugguc cuggcccugc      120

ugaacuuugc cacggucagc cucucucugu ccacuugcac caccuuggac uucggccaca      180

ucaagaagaa gaggguggaa gccauuaggg gacagaucuu gagcaagcuc aggcucacca      240

gccccccuga gccaacggug augacccacg uccccuauca gguccuggcc cuuuacaaca      300

gcacccggga gcugcuggag gagaugcaug gggagaggga ggaaggcugc acccaggaaa      360

acaccgaguc ggaauacuau gccaaagaaa uccauaaauu cgacaugauc caggggcugg      420

cggagcacaa cgaacuggcu gucugcccua aaggaauuac cuccaagguu uuccgcuuca      480

auguguccuc aguggagaaa aauagaacca accuauuccg agcagaguuc cgggucuugc      540

gggugcccaa ccccagcucu aagcggaaug agcagaggau cgagcuguuc cagauccuuc      600

ggccagauga gcacauugcc aaacagcgcu auaucggugg caagaaucug cccacacggg      660

gcacugccga guggcugucc uuugauguca cugacacugu gcgugagugg cuguugagaa      720

gagaguccaa cuuaggucua gaaaucagca uucacugucc augucacacc uuucagccca      780

auggagauau ccuggaaaac auucacgagg ugauggaaau caaauucaaa ggcguggaca      840

augaggauga ccauggccgu ggagaucugg ggcgccucaa gaagcagaag gaucaccaca      900

acccucaucu aauccucaug augauucccc cacaccggcu cgacaacccg ggccaggggg      960

gucagaggaa gaagcgggcu uuggacacca auuacugcuu ccgcaacuug gaggagaacu     1020

gcugugugcg cccccucuac auugacuucc gacaggaucu gggcuggaag uggguccaug     1080

aaccuaaggg cuacuaugcc aacuucugcu caggcccuug cccauaccuc cgcagugcag     1140

acacaaccca cagcacggug cugggacugu acaacacucu gaacccugaa gcaucugccu     1200

cgccuugcug cgugccccag gaccuggagc cccugaccau ccuguacuau guugggagga     1260

cccccaaagu ggagcagcuc uccaacaugg uggugaaguc uuguaaaugu agcugaggac     1320

uagugcauca cauuuaaaag caucucagcc uaccaugaga auaagagaaa gaaaaugaag     1380

aucaauagcu uauucaucuc uuuuucuuuu ucguuggugu aaagccaaca cccugucuaa     1440

aaaacauaaa uuucuuuaau cauuuugccu cuuuucucug ugcuucaauu aauaaaaaau     1500

ggaaagaacc uagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa agaauu                                          1586


<210>  6161
<211>  1733
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (wt)

<400>  6161
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgcccgucg ccgucugggc cgcgcuggcc gucggacugg      120

agcucugggc ugcggcgcac gccuugcccg cccagguggc auuuacaccc uacgccccgg      180

agcccgggag cacaugccgg cucagagaau acuaugacca gacagcucag augugcugca      240

gcaaaugcuc gccgggccaa caugcaaaag ucuucuguac caagaccucg gacaccgugu      300

gugacuccug ugaggacagc acauacaccc agcucuggaa cuggguuccc gagugcuuga      360

gcuguggcuc ccgcuguagc ucugaccagg uggaaacuca agccugcacu cgggaacaga      420

accgcaucug caccuguagg cccggcuggu acugcgcgcu gagcaagcag gaggggugcc      480

ggcugugcgc gccgcugcgc aagugccgcc cgggcuucgg cguggccaga ccaggaacug      540

aaacaucaga cguggugugc aagcccugug ccccggggac guucuccaac acgacuucau      600

ccacggauau uugcaggccc caccagaucu guaacguggu ggccaucccu gggaaugcaa      660

gcauggaugc agucugcacg uccacguccc ccacccggag uauggcccca ggggcaguac      720

acuuacccca gccagugucc acacgauccc aacacacgca gccaacucca gaacccagca      780

cugcuccaag caccuccuuc cugcucccaa ugggccccag ccccccagcu gaagggagca      840

cuggcgacuu cgcucugcca guuggacuga uugugggugu gacagccuug ggucuacuaa      900

uaauaggagu ggugaacugu gucaucauga cccaggugaa aaagaagccc uugugccugc      960

agagagaagc caaggugccu cacuugccug ccgauaaggc ccgggguaca cagggccccg     1020

agcagcagca ccuccugauc acagcgccga gcuccagcag cagcucccug gagagcucgg     1080

ccagugcguu ggacagaagg gcgcccacuc ggaaccagcc acaggcacca ggcguggagg     1140

ccaguggggc cggggaggcc cgggccagca ccgggagcuc agauucuucc ccugguggcc     1200

augggaccca ggucaauguc accuguaucg ugaacgucug uagcagcucu gaccacagcu     1260

cacagugcuc cucccaagcc agcuccacaa ugggagacac agauuccagc cccucggagu     1320

ccccgaagga cgagcagguc cccuucucca aggaggaaug ugccuuucgg ucacagcugg     1380

agacgccaga gacccugcug gggagcaccg aagagaagcc ccugccccuu ggagugccug     1440

augcugggau gaagcccagu uaaggacuag ugcaucacau uuaaaagcau cucagccuac     1500

caugagaaua agagaaagaa aaugaagauc aauagcuuau ucaucucuuu uucuuuuucg     1560

uugguguaaa gccaacaccc ugucuaaaaa acauaaauuu cuuuaaucau uuugccucuu     1620

uucucugugc uucaauuaau aaaaaaugga aagaaccuag aucuaaaaaa aaaaaaaaaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaga auu            1733


<210>  6162
<211>  1412
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design3 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (wt)

<400>  6162
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagagu ggguaguggu gaauguuuuc augauguugu      120

acguccagcu ggugcagggc uccaguaaug aacauggacc agugaagcga ucaucucagu      180

ccacauugga acgaucugaa cagcagauca gggcugcuuc uaguuuggag gaacuacuuc      240

gaauuacuca cucugaggac uggaagcugu ggagaugcag gcugaggcuc aaaaguuuua      300

ccaguaugga cucucgcuca gcaucccauc gguccacuag guuugcggca acuuucuaug      360

acauugaaac acuaaaaguu auagaugaag aauggcaaag aacucagugc agcccuagag      420

aaacgugcgu ggagguggcc agugagcugg ggaagaguac caacacauuc uucaagcccc      480

cuugugugaa cguguuccga ugugguggcu guugcaauga agagagccuu aucuguauga      540

acaccagcac cucguacauu uccaaacagc ucuuugagau aucagugccu uugacaucag      600

uaccugaauu agugccuguu aaaguugcca aucauacagg uuguaagugc uugccaacag      660

ccccccgcca uccauacuca auuaucagaa gauccaucca gaucccugaa gaagaucgcu      720

guucccauuc caagaaacuc uguccuauug acaugcuaug ggauagcaac aaauguaaau      780

guguuuugca ggaggaaaau ccacuugcug gaacagaaga ccacucucau cuccaggaac      840

cagcucucug ugggccacac augauguuug acgaagaucg uugcgagugu gucuguaaaa      900

caccaugucc caaagaucua auccagcacc ccaaaaacug caguugcuuu gagugcaaag      960

aaagucugga gaccugcugc cagaagcaca agcuauuuca cccagacacc uguagcugug     1020

aggacagaug ccccuuucau accagaccau gugcaagugg caaaacagca ugugcaaagc     1080

auugccgcuu uccaaaggag aaaagggcug cccaggggcc ccacagccga aagaauccuu     1140

gaggacuagu gcaucacauu uaaaagcauc ucagccuacc augagaauaa gagaaagaaa     1200

augaagauca auagcuuauu caucucuuuu ucuuuuucgu ugguguaaag ccaacacccu     1260

gucuaaaaaa cauaaauuuc uuuaaucauu uugccucuuu ucucugugcu ucaauuaaua     1320

aaaaauggaa agaaccuaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaagaa uu                                   1412


<210>  6163
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (wt)

<400>  6163
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuauauaa      180

gacauccgua cacuuccuau ggguacgaac ccaugggugg auggcugcac caccaaauca      240

uacccguggu gucgcagcag acuccccaga gucaugcccu ucagccucau caccacaucc      300

ccauggugcc agcucaacag cccgggaucc cccagcagcc aaugaugcca cuuccuggcc      360

aacacuccau gacuccaacc caacaccacc agccaaaccu cccucugccc gcccagcagc      420

ccuuccagcc ccagcccguc cagccccagc cucaccagcc ccugcagccc cagucaccca      480

ugcaccccau ccagcccuug cugccacagc caccucugcc uccgauguuc uccaugcagu      540

cucugcuucc ugaccugccu cuggaagcau ggccagcaac agacaagacc aagcgggagg      600

aaguggauua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  6164
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (wt)

<400>  6164
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuucuuugc cugccuuuug ggagcauccc      120

uugcuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccguacacu uccuaugggu      240

acgaacccau ggguggaugg cugcaccacc aaaucauacc cguggugucg cagcagacuc      300

cccagaguca ugcccuucag ccucaucacc acauccccau ggugccagcu caacagcccg      360

ggauccccca gcagccaaug augccacuuc cuggccaaca cuccaugacu ccaacccaac      420

accaccagcc aaaccucccu cugcccgccc agcagcccuu ccagccccag cccguccagc      480

cccagccuca ccagccccug cagccccagu cacccaugca ccccauccag cccuugcugc      540

cacagccacc ucugccuccg auguucucca ugcagucucu gcuuccugac cugccucugg      600

aagcauggcc agcaacagac aagaccaagc gggaggaagu ggauuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6165
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (wt)

<400>  6165
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccgucucug cuuccugacc      240

ugccucugga agcauggcca gcaacagaca agaccaagcg ggaggaagug gauuaaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  6166
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (wt)

<400>  6166
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

acuuauacuu ggaggcuauc cguauugaca ggacugcauu cgugcuuacc ccucugaagu      240

gguaccagaa caugauaaga cauccguaca cuuccuaugg uuacgaaccc auggguggau      300

ggcugcacca ccaaaucauu cccguggugu cgcagcagac uccccagagu caugcccuuc      360

agccucauca ccacaucccc auggugccag cucaacagcc cgggaucccc cagcagccaa      420

ugaugccacu uccuggccaa cacuccauga cuccaaccca acaccaccag ccaaaccucc      480

cucugcccgc ccagcagccc uuccagcccc agcccgucca gccccagccu caccagcccc      540

ugcagcccca gucacccaug caccccaucc agcccuugcu gccacagcca ccucugccuc      600

cgauguucuc caugcagucu cugcuuccug accugccucu ggaagcaugg ccagcaacag      660

acaagaccaa gcgggaggaa guggauuaag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  6167
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (wt)

<400>  6167
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccgacuccc cagagucaug      240

cccuucagcc ucaucaccac auccccaugg ugccagcuca acagcccggg aucccccagc      300

agccaaugau gccacuuccu ggccaacacu ccaugacucc aacccaacac caccagccaa      360

accucccucu gcccgcccag cagcccuucc agccccagcc cguccagccc cagccucacc      420

agccccugca gccccaguca cccaugcacc ccauccagcc cuugcugcca cagccaccuc      480

ugccuccgau guucuccaug cagucucugc uuccugaccu gccucuggaa gcauggccag      540

caacagacaa gaccaagcgg gaggaagugg auuaaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  6168
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (wt)

<400>  6168
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccucugaagu gguaccagaa caugauaaga cauccguaca      180

cuuccuaugg guacgaaccc auggguggau ggcugcacca ccaaaucaua cccguggugu      240

cgcagcagac uccccagagu caugcccuuc agccucauca ccacaucccc auggugccag      300

cucaacagcc cgggaucccc cagcagccaa ugaugccacu uccuggccaa cacuccauga      360

cuccaaccca acaccaccag ccaaaccucc cucugcccgc ccagcagccc uuccagcccc      420

agcccgucca gccccagccu caccagcccc ugcagcccca gucacccaug caccccaucc      480

agcccuugcu gccacagcca ccucugccuc cgauguucuc caugcagucu cugcuuccug      540

accugccucu ggaagcaugg ccagcaacag acaagaccaa gcgggaggaa guggauuaag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  6169
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (wt)

<400>  6169
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg cccgccugcc gcugcugcuc gggcugcugc      120

ugcucccgcg ucccggccgg ccgcuggacu uggccgacua caccuaugac cuggcggagg      180

aggacgacuc ggagccccuc aacuacaaag accccugcaa ggcggcugcc uuucuugggg      240

acauugcccu ggacgaagag gaccugaggg ccuuccaggu acagcaggcu guggaucuca      300

gacggcacac agcucguaag uccuccauca aagcugcagu uccaggaaac acuucuaccc      360

ccagcugcca gagcaccaac gggcagccuc agaggggagc cugugggaga uggagaggua      420

gaucccguag ccggcgggcg gcgacguccc gaccagagcg uguguggccc gaugggguca      480

uccccuuugu cauuggggga aacuucacug guagccagag ggcagucuuc cggcaggcca      540

ugaggcacug ggagaagcac accuguguca ccuuccugga gcgcacugac gaggacagcu      600

auauuguguu caccuaucga ccuugcgggu gcugcuccua cgugggucgc cgcggcgggg      660

gcccccaggc caucuccauc ggcaagaacu gugacaaguu cggcauugug guccacgagc      720

ugggccacgu cgucggcuuc uggcacgaac acacucggcc agaccgggac cgccacguuu      780

ccaucguucg ugagaacauc cagccagggc aggaguauaa cuuccugaag auggagccuc      840

aggaggugga gucccugggg gagaccuaug acuucgacag caucaugcau uacgcucgga      900

acacauucuc caggggcauc uuccuggaua ccauuguccc caaguaugag gugaacgggg      960

ugaaaccucc cauuggccaa aggacacggc ucagcaaggg ggacauugcc caagcccgca     1020

agcuguacaa gugcccagcc uguggagaga cccugcaaga cagcacaggc aacuucuccu     1080

ccccugaaua ccccaauggc uacucugcuc acaugcacug cguguggcgc aucucuguca     1140

cacccgggga gaagaucauc cugaacuuca cgucccugga ccuguaccgc agccgccugu     1200

gcugguacga cuauguggag guccgagaug gcuucuggag gaaggcgccc cuccgaggcc     1260

gcuucugcgg guccaaacuc ccugagccua ucgucuccac ugacagccgc cucuggguug     1320

aguuccgcag cagcagcaau uggguuggaa agggcuucuu ugcagucuac gaagccaucu     1380

gcggggguga ugugaaaaag gacuauggcc acauucaauc gcccaacuac ccagacgauu     1440

accggcccag caaagucugc aucuggcgga uccagguguc ugagggcuuc cacgugggcc     1500

ucacauucca guccuuugag auugagcgcc acgacagcug ugccuacgac uaucuggagg     1560

ugcgcgacgg gcacagugag agcagcaccc ucaucgggcg cuacuguggc uaugagaagc     1620

cugaugacau caagagcacg uccagccgcc ucuggcucaa guucgucucu gacgggucca     1680

uuaacaaagc gggcuuugcc gucaacuuuu ucaaagaggu ggacgagugc ucucggccca     1740

accgcggggg cugugagcag cggugccuca acacccuggg cagcuacaag ugcagcugug     1800

accccgggua cgagcuggcc ccagacaagc gccgcuguga ggcugcuugu ggcggauucc     1860

ucaccaagcu caacggcucc aucaccagcc cgggcuggcc caaggaguac ccccccaaca     1920

agaacugcau cuggcagcug guggccccca cccaguaccg caucucccug caguuugacu     1980

ucuuugagac agagggcaau gaugugugca aguacgacuu cguggaggug cgcaguggac     2040

ucacagcuga cuccaagcug cauggcaagu ucugugguuc ugagaagccc gaggucauca     2100

ccucccagua caacaacaug cgcguggagu ucaaguccga caacaccgug uccaaaaagg     2160

gcuucaaggc ccacuucuuc ucagacaagg acgagugcuc caaggauaac ggcggcugcc     2220

agcaggacug cgucaacacg uucggcaguu augagugcca augccgcagu ggcuucgucc     2280

uccaugacaa caagcacgac ugcaaagaag ccggcuguga ccacaaggug acauccacca     2340

gugguaccau caccagcccc aacuggccug acaaguaucc cagcaagaag gagugcacgu     2400

gggccaucuc cagcaccccc gggcaccggg ucaagcugac cuucauggag auggacaucg     2460

agucccagcc ugagugugcc uacgaccacc uagagguguu cgacgggcga gacgccaagg     2520

cccccguccu cggccgcuuc ugugggagca agaagcccga gcccguccug gccacaggca     2580

gccgcauguu ccugcgcuuc uacucagaua acucggucca gcgaaagggc uuccaggccu     2640

cccacgccac agagugcggg ggccagguac gggcagacgu gaagaccaag gaccuuuacu     2700

cccacgccca guuuggcgac aacaacuacc cugggggugu ggacugugag ugggucauug     2760

uggccgagga aggcuacggc guggagcucg uguuccagac cuuugaggug gaggaggaga     2820

ccgacugcgg cuaugacuac auggagcugu ucgacggcua cgacagcaca gcccccaggc     2880

uggggcgcua cuguggcuca gggccuccug aggaggugua cucggcggga gauucugucc     2940

uggugaaguu ccacucggau gacaccauca ccaaaaaagg uuuccaccuc cgauacacca     3000

gcaccaaguu ccaggacaca cuccacagca ggaagugagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  6170
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (wt)

<400>  6170
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggga cccgcugucu ucuagcguug cugcuucccc      120

agguccuccu gggcggcgcg gcuggccucg uuccggagcu gggccgcagg aaguucgcgg      180

cggcgucguc gggccgcccc ucaucccagc ccucugacga gguccugagc gaguucgagu      240

ugcggcugcu cagcauguuc ggccugaaac agagacccac ccccagcagg gacgccgugg      300

ugccccccua caugcuagac cuguaucgca ggcacucagg ucagccgggc ucacccgccc      360

cagaccaccg guuggagagg gcagccagcc gagccaacac ugugcgcagc uuccaccaug      420

aagaaucuuu ggaagaacua ccagaaacga gugggaaaac aacccggaga uucuucuuua      480

auuuaaguuc uauccccacg gaggaguuua ucaccucagc agagcuucag guuuuccgag      540

aacagaugca agaugcuuua ggaaacaaua gcaguuucca ucaccgaauu aauauuuaug      600

aaaucauaaa accugcaaca gccaacucga aauuccccgu gaccagacuu uuggacacca      660

gguuggugaa ucagaaugca agcagauggg aaaguuuuga ugucaccccc gcugugaugc      720

gguggacugc acagggacac gccaaccaug gauucguggu ggaaguggcc cacuuggagg      780

agaaacaagg ugucuccaag agacauguua ggauaagcag gucuuugcac caagaugaac      840

acagcugguc acagauaagg ccauugcuag uaacuuuugg ccaugaugga aaagggcauc      900

cucuccacaa aagagaaaaa cgucaagcca aacacaaaca gcggaaacgc cuuaagucca      960

gcuguaagag acacccuuug uacguggacu ucagugacgu gggguggaau gacuggauug     1020

uggcuccccc gggguaucac gccuuuuacu gccacggaga augcccuuuu ccucuggcug     1080

aucaucugaa cuccacuaau caugccauug uucagacguu ggucaacucu guuaacucua     1140

agauuccuaa ggcaugcugu gucccgacag aacucagugc uaucucgaug cuguaccuug     1200

acgagaauga aaagguugua uuaaagaacu aucaggacau gguuguggag gguugugggu     1260

gucgcuaggg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  6171
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (wt)

<400>  6171
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auuccuggua accgaaugcu gauggucguu uuauuaugcc      120

aaguccugcu aggaggcgcg agccaugcua guuugauacc ugagacgggg aagaaaaaag      180

ucgccgagau ucagggccac gcgggaggac gccgcucagg gcagagccau gagcuccugc      240

gggacuucga ggcgacacuu cugcagaugu uugggcugcg ccgccgcccg cagccuagca      300

agagugccgu cauuccggac uacaugcggg aucuuuaccg gcuucagucu ggggaggagg      360

aggaagaaca gauccacagc acuggucuug aguauccuga gcgcccggcc agccgggcca      420

acaccgugag gagcuuccac cacgaagaac aucuggagaa caucccaggg accagugaaa      480

acucugcuuu ucguuuccuc uuuaaccuca gcagcauccc ugagaacgag gugaucuccu      540

cugcagagcu ucggcuguuc cgggagcagg ucgaccaggg cccugauugg gaaaggggcu      600

uccaccguau aaacauuuau gagguuauga agcccccagc agaaguggug ccugggcacc      660

ucaucacacg acuacuggac acgagacugg uccaccacaa ugugacacgg ugggaaacuu      720

uugaugugag cccugcgguc cuucgcugga cccgggagaa gcagccaaac uaugggcuag      780

ccauugaggu gacucaccuc caucagacuc ggacccacca gggccagcau gucaggauua      840

gccgaucguu accucaaggg agugggaauu gggcccagcu ccggccccuc cuggucaccu      900

uuggccauga uggccggggc caugccuuga cccgacgccg gagggccaag cguagcccua      960

agcaucacuc acagcgggcc aggaagaaga auaagaacug ccggcgccac ucgcucuaug     1020

uggacuucag cgaugugggc uggaaugacu ggauuguggc cccaccaggc uaccaggccu     1080

ucuacugcca uggggacugc cccuuuccac uggcugacca ccucaacuca accaaccaug     1140

ccauugugca gacccugguc aauucuguca auuccaguau ccccaaagcc uguugugugc     1200

ccacugaacu gagugccauc uccaugcugu accuggauga guaugauaag gugguacuga     1260

aaaauuauca ggagauggua guagagggau gugggugccg cugaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  6172
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (wt)

<400>  6172
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggggcugg ggcggagggc gcaguggcug ugcugguggu      120

gggggcugcu gugcagcugc ugcgggcccc cgccgcugcg gccgcccuug cccgcugccg      180

cggccgccgc cgccgggggg cagcugcugg gggacggcgg gagccccggc cgcacggagc      240

agccgccgcc gucgccgcag uccuccucgg gcuuccugua ccggcggcuc aagacgcagg      300

agaagcggga gaugcagaag gagaucuugu cggugcuggg gcucccgcac cggccccggc      360

cccugcacgg ccuccaacag ccgcagcccc cggcgcuccg gcagcaggag gagcagcagc      420

agcagcagca gcugccucgc ggagagcccc cucccgggcg acugaagucc gcgccccucu      480

ucaugcugga ucuguacaac gcccuguccg ccgacaacga cgaggacggg gcgucggagg      540

gggagaggca gcaguccugg ccccacgaag cagccagcuc gucccagcgu cggcagccgc      600

ccccgggcgc cgcgcacccg cucaaccgca agagccuucu ggcccccgga ucuggcagcg      660

gcggcgcguc cccacugacc agcgcgcagg acagcgccuu ccucaacgac gcggacaugg      720

ucaugagcuu ugugaaccug guggaguacg acaaggaguu cuccccucgu cagcgacacc      780

acaaagaguu caaguucaac uuaucccaga uuccugaggg ugagguggug acggcugcag      840

aguuccgcau cuacaaggac uguguuaugg ggaguuuuaa aaaccaaacu uuucuuauca      900

gcauuuauca agucuuacag gagcaucagc acagagacuc ugaccuguuu uuguuggaca      960

cccguguagu augggccuca gaagaaggcu ggcuggaauu ugacaucacg gccacuagca     1020

aucugugggu ugugacucca cagcauaaca uggggcuuca gcugagcgug gugacaaggg     1080

auggagucca cguccacccc cgagccgcag gccugguggg cagagacggc ccuuacgaca     1140

agcagcccuu caugguggcu uucuucaaag ugagugaggu gcacgugcgc accaccaggu     1200

cagccuccag ccggcgccga caacagaguc guaaucgcuc uacccagucc caggacgugg     1260

cgcgggucuc cagugcuuca gauuacaaca gcagugaauu gaaaacagcc ugcaggaagc     1320

augagcugua ugugaguuuc caagaccugg gauggcagga cuggaucauu gcacccaagg     1380

gcuaugcugc caauuacugu gauggagaau gcuccuuccc acucaacgca cacaugaaug     1440

caaccaacca cgcgauugug cagaccuugg uucaccuuau gaaccccgag uaugucccca     1500

aaccgugcug ugcgccaacu aagcuaaaug ccaucucggu ucuuuacuuu gaugacaacu     1560

ccaaugucau ucugaaaaaa uacaggaaua ugguuguaag agcuugugga ugccacuaag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  6173
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (wt)

<400>  6173
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugcgcu cacugcgagc ugcggcgccg cacagcuucg      120

uggcgcucug ggcaccccug uuccugcugc gcuccgcccu ggccgacuuc agccuggaca      180

acgaggugca cucgagcuuc auccaccggc gccuccgcag ccaggagcgg cgggagaugc      240

agcgcgagau ccucuccauu uugggcuugc cccaccgccc gcgcccgcac cuccagggca      300

agcacaacuc ggcacccaug uucaugcugg accuguacaa cgccauggcg guggaggagg      360

gcggcgggcc cggcggccag ggcuucuccu accccuacaa ggccgucuuc aguacccagg      420

gccccccucu ggccagccug caagauagcc auuuccucac cgacgccgac auggucauga      480

gcuucgucaa ccucguggaa caugacaagg aguucuucca cccacgcuac caccaucgag      540

aguuccgguu ugaucuuucc aagaucccag aaggggaagc ugucacggca gccgaguucc      600

ggaucuacaa ggacuacauc cgggaacgcu ucgacaauga gacguuccgg aucagcguuu      660

aucaggugcu ccaggagcac uugggcaggg aaucggaucu cuuccugcuc gacagccgua      720

cccucugggc cucggaggag ggcuggcugg uguuugacau cacagccacc agcaaccacu      780

ggguggucaa uccgcggcac aaccugggcc ugcagcucuc gguggagacg cuggaugggc      840

agagcaucaa ccccaaguug gcgggccuga uugggcggca cgggccccag aacaagcagc      900

ccuucauggu ggcuuucuuc aaggccacgg agguccacuu ccgcagcauc cgguccacgg      960

ggagcaaaca gcgcagccag aaccgcucca agacgcccaa gaaccaggaa gcccugcgga     1020

uggccaacgu ggcagagaac agcagcagcg accagaggca ggccuguaag aagcacgagc     1080

uguaugucag cuuccgagac cugggcuggc aggacuggau caucgcgccu gaaggcuacg     1140

ccgccuacua cugugagggg gagugugccu ucccucugaa cuccuacaug aacgccacca     1200

accacgccau cgugcagacg cugguccacu ucaucaaccc ggaaacggug cccaagcccu     1260

gcugugcgcc cacgcagcuc aaugccaucu ccguccucua cuucgaugac agcuccaacg     1320

ucauccugaa gaaauacaga aacauggugg uccgggccug uggcugccac uagggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  6174
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (wt)

<400>  6174
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagccucug cagcacuucu gugucugcug cucacagcag      120

cugcuuucag cccccagggg cuugcucagc caguugggau uaauacuuca acuaccugcu      180

gcuacagauu uaucaauaag aaaaucccua agcagaggcu ggagagcuac agaaggacca      240

ccaguagcca cuguccccgg gaagcuguaa ucuucaagac caaacuggac aaggagaucu      300

gugcugaccc cacacagaag uggguccagg acuuuaugaa gcaccuggac aagaaaaccc      360

aaacuccaaa gcugugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  6175
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (wt)

<400>  6175
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucacuc uuaucauucu guugccagua guuucaaaau      120

uuaguuuugu uagucucuca gcaccgcagc acuggagcug uccugaaggu acucucgcag      180

gaaauggcaa uucuacuugu guggguccug cacccuucuu aauuuucucc cauggaaaua      240

guaucuuuag gauugacaca gaaggaacca auuaugagca auugguggug gaugcuggug      300

ucucagugau cauggauuuu cauuauaaug agaaaagaau cuauugggug gauuuagaaa      360

gacaacuuuu gcaaagaguu uuucugaaug ggucaaggca agagagagua uguaauauag      420

agaaaaaugu uucuggaaug gcaauaaauu ggauaaauga agaaguuauu uggucaaauc      480

aacaggaagg aaucauuaca guaacagaua ugaaaggaaa uaauucccac auucuuuuaa      540

gugcuuuaaa auauccugca aauguagcag uugauccagu agaaagguuu auauuuuggu      600

cuucagaggu ggcuggaagc cuuuauagag cagaucucga ugguguggga gugaaggcuc      660

uguuggagac aucagagaaa auaacagcug ugucauugga ugugcuugau aagcggcugu      720

uuuggauuca guacaacaga gaaggaagca auucucuuau uugcuccugu gauuaugaug      780

gagguucugu ccacauuagu aaacauccaa cacagcauaa uuuguuugca augucccuuu      840

uuggugaccg uaucuucuau ucaacaugga aaaugaagac aauuuggaua gccaacaaac      900

acacuggaaa ggacaugguu agaauuaacc uccauucauc auuuguacca cuuggugaac      960

ugaaaguagu gcauccacuu gcacaaccca aggcagaaga ugacacuugg gagccugagc     1020

agaaacuuug caaauugagg aaaggaaacu gcagcagcac uguguguggg caagaccucc     1080

agucacacuu gugcaugugu gcagagggau acgcccuaag ucgagaccgg aaguacugug     1140

aagauguuaa ugaaugugcu uuuuggaauc auggcuguac ucuugggugu aaaaacaccc     1200

cuggauccua uuacugcacg ugcccuguag gauuuguucu gcuuccugau gggaaacgau     1260

gucaucaacu uguuuccugu ccacgcaaug ugucugaaug cagccaugac uguguucuga     1320

caucagaagg ucccuuaugu uucuguccug aaggcucagu gcuugagaga gaugggaaaa     1380

cauguagcgg uuguuccuca cccgauaaug guggauguag ccagcucugc guuccucuua     1440

gcccaguauc cugggaaugu gauugcuuuc cuggguauga ccuacaacug gaugaaaaaa     1500

gcugugcagc uucaggacca caaccauuuu ugcuguuugc caauucucaa gauauucgac     1560

acaugcauuu ugauggaaca gacuauggaa cucugcucag ccagcagaug ggaaugguuu     1620

augcccuaga ucaugacccu guggaaaaua agauauacuu ugcccauaca gcccugaagu     1680

ggauagagag agcuaauaug gaugguuccc agcgagaaag gcuuauugag gaaggaguag     1740

augugccaga aggucuugcu guggacugga uuggccguag auucuauugg acagacagag     1800

ggaaaucucu gauuggaagg agugauuuaa augggaaacg uuccaaaaua aucacuaagg     1860

agaacaucuc ucaaccacga ggaauugcug uucauccaau ggccaagaga uuauucugga     1920

cugauacagg gauuaaucca cgaauugaaa guucuucccu ccaaggccuu ggccgucugg     1980

uuauagccag cucugaucua aucuggccca guggaauaac gauugacuuc uuaacugaca     2040

aguuguacug gugcgaugcc aagcagucug ugauugaaau ggccaaucug gaugguucaa     2100

aacgccgaag acuuacccag aaugauguag gucacccauu ugcuguagca guguuugagg     2160

auuaugugug guucucagau ugggcuaugc caucaguaau gagaguaaac aagaggacug     2220

gcaaagauag aguacgucuc caaggcagca ugcugaagcc cucaucacug guugugguuc     2280

auccauuggc aaaaccagga gcagaucccu gcuuauauca aaacggaggc ugugaacaua     2340

uuugcaaaaa gaggcuugga acugcuuggu guucgugucg ugaagguuuu augaaagccu     2400

cagaugggaa aacgugucug gcucuggaug gucaucagcu guuggcagga ggugaaguug     2460

aucuaaagaa ccaaguaaca ccauuggaca ucuuguccaa gacuagagug ucagaagaua     2520

acauuacaga aucucaacac augcuagugg cugaaaucau ggugucagau caagaugacu     2580

gugcuccugu gggaugcagc auguaugcuc gguguauuuc agagggagag gaugccacau     2640

gucaguguuu gaaaggauuu gcuggggaug gaaaacuaug uucugauaua gaugaaugug     2700

agaugggugu cccagugugc cccccugccu ccuccaagug caucaacacc gaaggugguu     2760

augucugccg gugcucagaa ggcuaccaag gagaugggau ucacugucuu gauauugaug     2820

agugccaacu gggggagcac agcuguggag agaaugccag cugcacaaau acagagggag     2880

gcuauaccug caugugugcu ggacgccugu cugaaccagg acugauuugc ccugacucua     2940

cuccaccccc ucaccucagg gaagaugacc accacuauuc cguaagaaau agugacucug     3000

aauguccccu gucccacgau ggguacugcc uccaugaugg ugugugcaug uauauugaag     3060

cauuggacaa guaugcaugc aacuguguug uuggcuacau cggggagcga ugucaguacc     3120

gagaccugaa guggugggaa cugcgccacg cuggccacgg gcagcagcag aaggucaucg     3180

ugguggcugu cugcguggug gugcuuguca ugcugcuccu ccugagccug uggggggccc     3240

acuacuacag gacucagaag cugcuaucga aaaacccaaa gaauccuuau gaggagucga     3300

gcagagaugu gaggagucgc aggccugcug acacugagga ugggaugucc ucuugcccuc     3360

aaccuugguu ugugguuaua aaagaacacc aagaccucaa gaaugggggu caaccagugg     3420

cuggugagga uggccaggca gcagaugggu caaugcaacc aacuucaugg aggcaggagc     3480

cccaguuaug uggaaugggc acagagcaag gcugcuggau uccaguaucc agugauaagg     3540

gcuccugucc ccagguaaug gagcggagcu uucauaugcc cuccuauggg acacagaccc     3600

uugaaggggg ugucgagaag ccccauucuc uccuaucagc uaacccauua uggcaacaaa     3660

gggcccugga cccaccacac caaauggagc ugacucagug aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  6176
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (wt)

<400>  6176
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgcgggga ggaggaugga gaugcucugu gccggcaggg      120

ucccugcgcu gcugcucugc cuggguuucc aucuucuaca ggcaguccuc aguacaacug      180

ugauuccauc auguauccca ggagagucca gugauaacug cacagcuuua guucagacag      240

aagacaaucc acguguggcu caagugucaa uaacaaagug uagcucugac augaauggcu      300

auuguuugca uggacagugc aucuaucugg uggacaugag ucaaaacuac ugcagaugug      360

aaguggguua uacugguguc cgaugugaac acuucuuuuu aaccguccac caaccuuuaa      420

gcaaagaaua uguggcuuug accgugauuc uuauuauuuu guuucuuauc acagucgucg      480

guuccacaua uuauuucugc agaugguaca gaaaucgaaa aaguaaagaa ccaaagaagg      540

aauaugagag aguuaccuca ggggauccag aguugccgca agucugagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  6177
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (wt)

<400>  6177
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggugugg gggguggaga uguagaagau gugacgccgc      120

ggcccggcgg gugccagauu agcggacgcg gugcccgcgg uugcaacggg aucccgggcg      180

cugcagcuug ggaggcggcu cuccccaggc ggcguccgcg gagacaccca uccgugaacc      240

ccaggucccg ggccgccggc ucgccgcgca ccaggggccg gcggacagaa gaacggccga      300

gcggcucgag gcugggggac cgcgggcgcg gccgcgcgcu gccgggcggg aggcuggggg      360

gccggggccg gggccgugcc ccggagcggg ucggaggccg gggccggggc cgggggacgg      420

cggcuccccg cgcggcucca gcggcucggg gaucccggcc gggccccgca gggaccaugg      480

cagccgggag caucaccacg cugcccgccu ugcccgagga uggcggcagc ggcgccuucc      540

cgcccggcca cuucaaggac cccaagcggc uguacugcaa aaacgggggc uucuuccugc      600

gcauccaccc cgacggccga guugacgggg uccgggaaaa gagcgacccu cacaucaagc      660

uacaacuuca agcagaagag agaggaguug ugucuaucaa aggagugugu gcuaaccguu      720

accuggcuau gaaggaagau ggaagauuac uggcuucuaa auguguuacg gaugaguguu      780

ucuuuuuuga acgauuggaa ucuaauaacu acaauacuua ccggucaagg aaauacacca      840

guugguaugu ggcacugaaa cgaacugggc aguauaaacu uggauccaaa acaggaccug      900

ggcagaaagc uauacuuuuu cuuccaaugu cugcuaagag cugaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  6178
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (wt)

<400>  6178
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uacugacaug gauccugcca acuuugcucu      120

acagaucaug cuuucacauu aucugucuag uggguacuau aucuuuagcu ugcaaugaca      180

ugacuccaga gcaaauggcu acaaauguga acuguuccag cccugagcga cacacaagaa      240

guuaugauua cauggaagga ggggauauaa gagugagaag acucuucugu cgaacacagu      300

gguaccugag gaucgauaaa agaggcaaag uaaaagggac ccaagagaug aagaauaauu      360

acaauaucau ggaaaucagg acaguggcag uuggaauugu ggcaaucaaa gggguggaaa      420

gugaguucua ucuugcaaug aacaaggaag gaaaacucua ugcaaagaaa gaaugcaaug      480

aagauuguaa cuucaaagaa cuaauucugg aaaaccauua caacacauau gcaucagcua      540

aauggacaca caacggaggg gaaauguuug uugccuuaaa ucaaaagggg auuccuguaa      600

gaggaaaaaa aacgaagaaa gaacaaaaaa cagcccacuu ucuuccuaug gcaauaacuu      660

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  6179
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (wt)

<400>  6179
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca aacuccugcc agcccugcug cugcagcaug      120

uccuccugca ucuccuccug cuccccaucg ccauccccua ugcagaggga caaaggaaaa      180

gaagaaauac aauucaugag uucaaaaaau cagcaaagac uacccuaauc aaaauagauc      240

cagcacugaa gauaaaaacc aaaaaaguga auacugcaga ccaaugugcu aauagaugua      300

cuaggaauaa aggacuucca uucacuugca aggcuuuugu uuuugauaaa gcaagaaaac      360

aaugccucug guuccccuuc aauagcaugu caaguggagu gaaaaaagaa uuuggccaug      420

aauuugaccu cuaugaaaac aaagacuaca uuagaaacug caucauuggu aaaggacgca      480

gcuacaaggg aacaguaucu aucacuaaga guggcaucaa augucagccc uggaguucca      540

ugauaccaca cgaacacagc uuuuugccuu cgagcuaucg ggguaaagac cuacaggaaa      600

acuacugucg aaauccucga ggggaagaag ggggacccug guguuucaca agcaauccag      660

agguacgcua cgaagucugu gacauuccuc aguguucaga aguugaaugc augaccugca      720

auggggagag uuaucgaggu cucauggauc auacagaauc aggcaagauu ugucagcgcu      780

gggaucauca gacaccacac cggcacaaau ucuugccuga aagauauccc gacaagggcu      840

uugaugauaa uuauugccgc aaucccgaug gccagccgag gccauggugc uauacucuug      900

acccucacac ccgcugggag uacugugcaa uuaaaacaug cgcugacaau acuaugaaug      960

acacugaugu uccuuuggaa acaacugaau gcauccaagg ucaaggagaa ggcuacaggg     1020

gcacugucaa uaccauuugg aauggaaucc caugucagcg uugggauucu caguauccuc     1080

acgagcauga caugacuccu gaaaauuuca agugcaagga ccuacgagaa aauuacugcc     1140

gaaauccaga ugggucugaa ucacccuggu guuuuaccac ugauccaaac auccgaguug     1200

gcuacugcuc ccaaauucca aacugugaua ugucacaugg acaagauugu uaucguggga     1260

auggcaaaaa uuauaugggc aacuuauccc aaacaagauc uggacuaaca uguucaaugu     1320

gggacaagaa cauggaagac uuacaucguc auaucuucug ggaaccagau gcaaguaagc     1380

ugaaugagaa uuacugccga aauccagaug augaugcuca uggacccugg ugcuacacgg     1440

gaaauccacu cauuccuugg gauuauugcc cuauuucucg uugugaaggu gauaccacac     1500

cuacaauagu caauuuagac caucccguaa uaucuugugc caaaacgaaa caauugcgag     1560

uuguaaaugg gauuccaaca cgaacaaaca uaggauggau gguuaguuug agauacagaa     1620

auaaacauau cugcggagga ucauugauaa aggagaguug gguucuuacu gcacgacagu     1680

guuucccuuc ucgagacuug aaagauuaug aagcauggcu uggaauccau gauguccacg     1740

gaagaggaga ugagaaaugc aaacagguuc ucaauguuuc ccagcuggua uauggcccug     1800

aaggaucaga ucugguuuua augaagcugg ccaggccugc uguccuggau gauuuuguua     1860

guacgauuga uuuaccuaau uauggaugca caauuccuga aaagaccagu ugcaguguuu     1920

auggcugggg cuacacugga uugaucaacu augauggccu auuacgagug gcacaucucu     1980

auauaauggg aaaugagaaa ugcagccagc aucaucgagg gaaggugacu cugaaugagu     2040

cugaaauaug ugcuggggcu gaaaagauug gaucaggacc augugagggg gauuauggug     2100

gcccacuugu uugugagcaa cauaaaauga gaaugguucu uggugucauu guuccugguc     2160

guggaugugc cauuccaaau cguccuggua uuuuuguccg aguagcauau uaugcaaaau     2220

ggauacacaa aauuauuuua acauauaagg uaccacaguc auagggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  6180
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (wt)

<400>  6180
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaagccg cggcgaucgg caucgaccug ggcaccaccu      120

acuccugcgu ggggguguuc caacacggca agguggagau caucgccaac gaccagggca      180

accgcaccac ccccagcuac guggccuuca cggacaccga gcggcucauc ggggaugcgg      240

ccaagaacca gguggcgcug aacccgcaga acaccguguu ugacgcgaag cggcugauug      300

gccgcaaguu cggcgacccg guggugcagu cggacaugaa gcacuggccu uuccagguga      360

ucaacgacgg agacaagccc aaggugcagg ucagcuacaa gggggagacc aaggcauucu      420

accccgagga gaucucgucc auggugcuga ccaagaugaa ggagaucgcc gaggcguacc      480

ugggcuaccc ggugaccaac gcggugauca ccgugccggc cuacuucaac gacucgcagc      540

gccaggccac caaggaugcg ggugugaucg cggggcucaa cgugcugcgg aucaucaacg      600

agcccacggc cgccgccauc gccuacggcc uggacagaac gggcaagggg gagcgcaacg      660

ugcucaucuu ugaccugggc gggggcaccu ucgacguguc cauccugacg aucgacgacg      720

gcaucuucga ggugaaggcc acggccgggg acacccaccu ggguggggag gacuuugaca      780

acaggcuggu gaaccacuuc guggaggagu ucaagagaaa acacaagaag gacaucagcc      840

agaacaagcg agccgugagg cggcugcgca ccgccugcga gagggccaag aggacccugu      900

cguccagcac ccaggccagc cuggagaucg acucccuguu ugagggcauc gacuucuaca      960

cguccaucac cagggcgagg uucgaggagc ugugcuccga ccuguuccga agcacccugg     1020

agcccgugga gaaggcucug cgcgacgcca agcuggacaa ggcccagauu cacgaccugg     1080

uccuggucgg gggcuccacc cgcaucccca aggugcagaa gcugcugcag gacuucuuca     1140

acgggcgcga ccugaacaag agcaucaacc ccgacgaggc uguggccuac ggggcggcgg     1200

ugcaggcggc cauccugaug ggggacaagu ccgagaacgu gcaggaccug cugcugcugg     1260

acguggcucc ccugucgcug gggcuggaga cggccggagg cgugaugacu gcccugauca     1320

agcgcaacuc caccaucccc accaagcaga cgcagaucuu caccaccuac uccgacaacc     1380

aacccggggu gcugauccag guguacgagg gcgagagggc caugacgaaa gacaacaauc     1440

uguuggggcg cuucgagcug agcggcaucc cuccggcccc caggggcgug ccccagaucg     1500

aggugaccuu cgacaucgau gccaacggca uccugaacgu cacggccacg gacaagagca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg ccgccugagc aaggaggaga     1620

ucgagcgcau ggugcaggag gcggagaagu acaaagcgga ggacgaggug cagcgcgaga     1680

gggugucagc caagaacgcc cuggaguccu acgccuucaa caugaaaagc gccguggagg     1740

augaggggcu caagggcaag aucagcgagg cggacaagaa gaaggugcug gacaaguguc     1800

aagaggucau cucguggcug gacgccaaca ccuuggccga gaaggacgag uuugagcaca     1860

agaggaagga gcuggagcag gucuguaacc ccaucaucag cggacuguac cagggugccg     1920

guggucccgg gccugggggc uucggggcuc agggucccaa gggagggucu gggucaggcc     1980

ccaccauuga ggagguagau uagggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6181
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (wt)

<400>  6181
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaagccg cggcgaucgg caucgaccug ggcaccaccu      120

acuccugcgu ggggguguuc caacacggca agguggagau caucgccaac gaccagggca      180

accgcaccac ccccagcuac guggccuuca cggacaccga gcggcucauc ggggaugcgg      240

ccaagaacca gguggcgcug aacccgcaga acaccguguu ugacgcgaag cggcugauug      300

gccgcaaguu cggcgacccg guggugcagu cggacaugaa gcacuggccu uuccagguga      360

ucaacgacgg agacaagccc aaggugcagg ucagcuacaa gggggagacc aaggcauucu      420

accccgagga gaucucgucc auggugcuga ccaagaugaa ggagaucgcc gaggcguacc      480

ugggcuaccc ggugaccaac gcggugauca ccgugccggc cuacuucaac gacucgcagc      540

gccaggccac caaggaugcg ggugugaucg cggggcucaa cgugcugcgg aucaucaacg      600

agcccacggc cgccgccauc gccuacggcc uggacagaac gggcaagggg gagcgcaacg      660

ugcucaucuu ugaccugggc gggggcaccu ucgacguguc cauccugacg aucgacgacg      720

gcaucuucga ggugaaggcc acggccgggg acacccaccu ggguggggag gacuuugaca      780

acaggcuggu gaaccacuuc guggaggagu ucaagagaaa acacaagaag gacaucagcc      840

agaacaagcg agccgugagg cggcugcgca ccgccugcga gagggccaag aggacccugu      900

cguccagcac ccaggccagc cuggagaucg acucccuguu ugagggcauc gacuucuaca      960

cguccaucac cagggcgagg uucgaggagc ugugcuccga ccuguuccga agcacccugg     1020

agcccgugga gaaggcucug cgcgacgcca agcuggacaa ggcccagauu cacgaccugg     1080

uccuggucgg gggcuccacc cgcaucccca aggugcagaa gcugcugcag gacuucuuca     1140

acgggcgcga ccugaacaag agcaucaacc ccgacgaggc uguggccuac ggggcggcgg     1200

ugcaggcggc cauccugaug ggggacaagu ccgagaacgu gcaggaccug cugcugcugg     1260

acguggcucc ccugucgcug gggcuggaga cggccggagg cgugaugacu gcccugauca     1320

agcgcaacuc caccaucccc accaagcaga cgcagaucuu caccaccuac uccgacaacc     1380

aacccggggu gcugauccag guguacgagg gcgagagggc caugacgaaa gacaacaauc     1440

uguuggggcg cuucgagcug agcggcaucc cuccggcccc caggggcgug ccccagaucg     1500

aggugaccuu cgacaucgau gccaacggca uccugaacgu cacggccacg gacaagagca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg ccgccugagc aaggaggaga     1620

ucgagcgcau ggugcaggag gcggagaagu acaaagcgga ggacgaggug cagcgcgaga     1680

gggugucagc caagaacgcc cuggaguccu acgccuucaa caugaaaagc gccguggagg     1740

augaggggcu caagggcaag aucagcgagg cggacaagaa gaagguucug gacaaguguc     1800

aagaggucau cucguggcug gacgccaaca ccuuggccga gaaggacgag uuugagcaca     1860

agaggaagga gcuggagcag gucuguaacc ccaucaucag cggacuguac cagggugccg     1920

guggucccgg gccuggcggc uucggggcuc agggucccaa gggagggucu gggucaggcc     1980

cuaccauuga ggagguggau uagggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6182
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (wt)

<400>  6182
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuacugcca agggaaucgc cauaggcauc gaccugggca      120

ccaccuacuc cugugugggg guguuccagc acggcaaggu ggagaucauc gccaacgacc      180

agggcaaccg caccaccccc agcuacgugg ccuucacaga caccgagcgg cucauugggg      240

augcggccaa gaaccaggua gcaaugaauc cccagaacac uguuuuugau gcuaaacguc      300

ugaucggcag gaaauuuaau gauccuguug uacaagcaga uaugaaacuu uggccuuuuc      360

aagugauuaa ugaaggaggc aagcccaaag uccuuguguc cuacaaaggg gagaauaaag      420

cauucuaccc ugaggaaauc ucuucgaugg uauugacuaa guugaaggag acugcugagg      480

ccuuuuuggg ccacccuguc accaaugcag ugauuaccgu gccagccuau uucaaugacu      540

cucaacguca ggcuacuaag gaugcaggag ugauugcugg acuuaaugug cuaagaauca      600

ucaaugagcc cacggcugcu gccauugccu augguuuaga uaaaggaggu caaggagaac      660

gacauguccu gauuuuugau cuggguggag gcacauuuga ugugucaauu cugaccauag      720

augaugggau uuuugaggua aaggccacug cuggggacac ucaccugggu ggggaggacu      780

uugacaacag gcuugugagc cacuucgugg aggaguucaa gaggaaacac aaaaaggaca      840

ucagccagaa caagcgagcc gugaggcggc ugcgcaccgc cugcgagagg gccaagagga      900

cccugucguc cagcacccag gccaaccuag aaauugauuc acuuuaugaa ggcauugacu      960

ucuauacauc caucaccaga gcucgauuug aagaguugug ugcagaccug uuuaggggua     1020

cccuggagcc uguagaaaaa gcgcuucggg augccaagau ggauaaggcu aaaauccaug     1080

acauuguuuu aguagggggc uccacccgca uccccaaggu gcagcggcug cuucaggacu     1140

acuucaaugg acgugaucuc aacaagagca ucaacccuga ugaggccgua gcauaugggg     1200

cugcgguaca agcagccauc cugauggggg acaagucuga gaagguacag gaccugcugc     1260

ugcuggacgu ggcuccccug ucccuggggc uggagacggc ugggggcgug augacugccc     1320

ugauaaagcg caacuccacc auccccacca agcagacaca gauuuucacc accuacucug     1380

acaaccaacc cggggugcug auccaggugu augagggcga gagggccaug acaaaggaca     1440

acaaccugcu ggggcgguuu gaccugacug gaaucccucc agcacccagg ggaguuccuc     1500

agaucgaggu gacguuugac auugaugcca augguauucu caaugucaca gccacggaca     1560

agagcaccgg caaggugaac aagaucacca ucaccaauga caagggccgc cugagcaagg     1620

aggagauuga gcgcaugguu cuggaugcug agaaauauaa agcugaagau gagguccaga     1680

gggagaaaau ugcugcaaag aaugccuuag aauccuaugc uuuuaacaug aagaguguug     1740

ugagugauga agguuugaag ggcaagauua gugagucuga uaaaaauaaa auauuggaua     1800

aaugcaacga gcuccuuucg uggcuggagg ucaaucaacu ggcagagaaa gaugaguuug     1860

aucauaagag aaaggaauug gagcagaugu guaacccuau caucacaaaa cucuaccaag     1920

gaggaugcac ugggccugcc ugcggaacag gguaugugcc uggaaggccu gccacaggcc     1980

ccacaauuga agaaguagau uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6183
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (wt)

<400>  6183
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucgguggugg gcauagaccu gggcuuccag agcugcuacg      120

ucgcuguggc ccgcgccggc ggcaucgaga cuaucgcuaa ugaguauagc gaccgcugca      180

cgccggcuug cauuucuuuu gguccuaaga aucguucaau uggagcagca gcuaaaagcc      240

agguaauuuc uaaugcaaag aacacagucc aaggauuuaa aagauuccau ggccgagcau      300

ucucugaucc auuuguggag gcagaaaaau cuaaccuugc auaugauauu gugcaguugc      360

cuacaggauu aacagguaua aaggugacau auauggagga agaacgaaau uuuaccacug      420

agcaagugac ugccaugcuu uuguccaaac ugaaggagac agccgaaagu guucuuaaga      480

agccuguagu ugacuguguu guuucgguuc cuuguuucua uacugaugca gaaagacgau      540

cagugaugga ugcaacacag auugcugguc uuaauugcuu gcgauuaaug aaugaaacca      600

cugcaguugc ucuugcauau ggaaucuaua agcaggaucu uccugccuua gaagagaaac      660

caagaaaugu aguuuuugua gacaugggcc acucugcuua ucaaguuucu guaugugcau      720

uuaauagagg aaaacugaaa guucuggcca cugcauuuga cacgacauug ggagguagaa      780

aauuugauga aguguuagua aaucacuucu gugaagaauu ugggaagaaa uacaagcuag      840

acauuaaguc caaaauccgu gcauuauuac gacucucuca ggagugugag aaacucaaga      900

aauugaugag ugcaaaugcu ucagaucucc cuuugagcau ugaauguuuu augaaugaug      960

uugauguauc uggaacuaug aauagaggca aauuucugga gaugugcaau gaucucuuag     1020

cuagagugga gccaccacuu cguaguguuu uggaacaaac caaguuaaag aaagaagaua     1080

uuuaugcagu ggagauaguu gguggugcua cacgaauccc ugcgguaaaa gagaagauca     1140

gcaaauuuuu cgguaaagaa cuuaguacaa cauuaaaugc ugaugaagcu gucacucgag     1200

gcugugcauu gcagugugcc aucuuaucgc cugcuuucaa agucagagaa uuuucuauca     1260

cugauguagu accauaucca auaucucuga gauggaacuc uccagcugaa gaagggucaa     1320

gugacuguga agucuuuucc aaaaaucaug cugcuccuuu cucuaaaguu cuuacauuuu     1380

auagaaagga accuuucacu cuugaggccu acuacagcuc uccucaggau uugcccuauc     1440

cagauccugc uauagcucag uuuucaguuc agaaagucac uccucagucu gauggcucca     1500

guucaaaagu gaaagucaaa guucgaguaa auguccaugg cauuuucagu guguccagug     1560

caucuuuagu ggagguucac aagucugagg aaaaugagga gccaauggaa acagaucaga     1620

augcaaagga ggaagagaag augcaagugg accaggagga accacauguu gaagaacaac     1680

agcagcagac accagcagaa aauaaggcag agucugaaga aauggagacc ucucaagcug     1740

gauccaagga uaaaaagaug gaccaaccac cccaagccaa gaaggcaaaa gugaagacca     1800

guacugugga ccugccaauc gagaaucagc uauuauggca gauagacaga gagaugcuca     1860

acuuguacau ugaaaaugag gguaagauga ucaugcagga uaaacuggag aaggagcgga     1920

augaugcuaa gaacgcagug gaggaauaug uguaugaaau gagagacaag cugaguggug     1980

aauaugagaa guuugugagu gaagaugauc guaacaguuu uacuuugaaa cuggaagaua     2040

cugaaaauug guuguaugag gauggagaag accagccaaa gcaaguuuau guugauaagu     2100

uggcugaauu aaaaaaucua ggucaaccua uuaagauacg uuuccaggaa ucugaagaac     2160

gaccaaaauu auuugaagaa cuagggaaac agauccaaca guauaugaaa auaaucagcu     2220

cuuucaaaaa caaggaggac caguaugauc auuuggaugc ugcugacaug acaaagguag     2280

aaaaaagcac aaaugaagca auggagugga ugaauaacaa gcuaaaucug cagaacaagc     2340

agaguuugac cauggaucca guugucaagu caaaagagau ugaagcuaaa auuaaggagc     2400

ugacaaguac uuguagcccu auaauuucaa agcccaaacc caaaguggaa ccuccaaaag     2460

aggaacaaaa aaaugcagag cagaauggac caguggaugg acaaggagac aacccaggcc     2520

cccaggcugc ugagcagggu acagacacag cugugccuuc ggauucagac aagaagcugc     2580

cugaaaugga cauugauuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  6184
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (wt)

<400>  6184
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucugugguug gcauugaccu cggcuuucuc aacugcuaca      120

uugcugucgc gagaaguggc ggcaucgaga ccaucgccaa ugaguacagc gacaggugua      180

ccccggccug uauaucauug ggaucaagaa cucgagccau uggaaaugca gcaaagagcc      240

agauagucac gaacguaaga aauacaauuc auggcuucaa aaagcugcau gggcgaucau      300

uugaugaucc cauugugcaa acugaaagga ucaggcuucc cuaugaacug cagaaaaugc      360

cuaauggaag ugcaggaguu aaggugcggu acuuagagga agagagaccu uuugcaauug      420

agcaaguuac uggaaugcug uuagccaagc ugaaagagac uucagaaaau gcuuugaaga      480

aaccaguggc ugacugugug auuucaauuc cuagcuuuuu uacugaugcc gagagaagau      540

cugugauggc ugcagcccag guugcaggcu uaaauuguuu aagguugaug aaugaaacua      600

cugcaguugc acuggcguau ggaauuuaua aacaggaucu ucccccauua gaugagaaac      660

caagaaaugu aguauuuauu gauaugggac auucugccua ucaggucuug guuugugcuu      720

uuaacaaagg aaaacuuaaa gucuuggcua cuaccuuuga uccauauuug gguggcagga      780

acuuugauga ggcuuuagua gacuacuucu gugaugaguu caagaccaaa uauaagauaa      840

augugaaaga aaacucucgg gccuuguugc guuuauauca ggaaugugaa aaacuaaaga      900

agcuaaugag ugcaaaugca ucagaucuuc cauugaacau ugaguguuuc augaaugacc      960

uugauguuuc uaguaaaaug aacagggcuc aauuugaaca acugugugcu ucccuuuugg     1020

ccaggguuga accaccuuua aaagcaguaa uggaacaagc uaacuuacaa cgugaagaca     1080

uuaguaguau agaaauugua ggaggagcaa cacgaauccc ugcagugaaa gaacaaauca     1140

cuaaauucuu ucuuaaagac auaaguacca cauuaaaugc ugaugaagcu guugcaagag     1200

gaugugcguu acagugugcg auucucucac cagcauuuaa agugcgugaa uuuuccauaa     1260

cagaccuugu ucccuauuca aucacauuaa gguggaagac cucuuuugaa gauggaagug     1320

gggaauguga aguuuucugu aagaaccauc cugccccauu cucaaaaguc auuacuuucc     1380

acaagaagga accauuugaa cuagaagcau uuuauacuaa uuuacaugaa gugccuuauc     1440

cugaugcaag aauugggagc uucacuauuc agaauguuuu uccacagucu gauggugaua     1500

guuccaaagu gaagguuaaa guucguguua acauccaugg aaucuucagu guggcuagcg     1560

caucaguaau ugagaagcaa aauuuggaag gcgaucacag ugaugcucca auggagacag     1620

aaacuucauu uaaaaaugaa aacaaagaua auauggauaa aaugcagguu gaucaagaag     1680

aagggcauca aaaaugucau gcugaacaca cuccagaaga ggaaauugau cauacaggag     1740

ccaaaacaaa gucagcuguc ucagacaaac aagaccgauu aaaucagaca cuuaaaaaag     1800

gaaaagucaa aaguauugau cuaccgaucc agaguagccu auguagacaa cuaggccaag     1860

aucuucucaa cagcuacauu gaaaaugagg ggaagaugau caugcaagau aaguuagaga     1920

aagaaagaaa ugaugcuaag aaugccguug aagaauaugu auaugauuuu agagacaggc     1980

ugggcacugu cuaugaaaaa uucaucacuc cagaagacuu gaguaaacug ucugcaguau     2040

uggaagacac agaaaauugg cuuuaugaag acggagagga ccaaccuaaa caaguuuaug     2100

uggauaagcu gcaagaacua aagaaauacg gccagccuau ucaaaugaag uacauggagc     2160

augaagagag accaaaagcc uuaaaugacu ugggaaaaaa gauccaacuu gucaugaaag     2220

ugauagaagc auauagaaac aaggaugaaa gauaugauca ucuggauccu acugaaaugg     2280

aaaagguuga aaaauguauc agugaugcca ugaguuggcu gaauaguaag augaaugcac     2340

agaacaaacu aagucucacu caagauccug ugguaaaagu uucagaaaua guagcaaagu     2400

caaaggaacu ggauaauuuc uguaacccca ucauuuacaa gcccaaacca aaagcagaag     2460

uuccugaaga caaaccaaaa gcuaauagug aacacaaugg cccaauggau ggacagagug     2520

gaacugaaac uaaaucagau ucaacaaaag acagcucaca gcauacuaaa uccucuggag     2580

agauggaagu ggacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  6185
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (wt)

<400>  6185
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcucuccc ugguggccgc gaugcugcug cugcucagcg      120

cggcgcgggc cgaggaggag gacaagaagg aggacguggg cacggugguc ggcaucgacc      180

uggggaccac cuacuccugc gucggcgugu ucaagaacgg ccgcguggag aucaucgcca      240

acgaucaggg caaccgcauc acgccguccu augucgccuu cacuccugaa ggggaacguc      300

ugauuggcga ugccgccaag aaccagcuca ccuccaaccc cgagaacacg gucuuugacg      360

ccaagcggcu caucggccgc acguggaaug acccgucugu gcagcaggac aucaaguucu      420

ugccguucaa ggugguugaa aagaaaacua aaccauacau ucaaguugau auuggaggug      480

ggcaaacaaa gacauuugcu ccugaagaaa uuucugccau gguucucacu aaaaugaaag      540

aaaccgcuga ggcuuauuug ggaaagaagg uuacccaugc aguuguuacu guaccagccu      600

auuuuaauga ugcccaacgc caagcaacca aagacgcugg aacuauugcu ggccuaaaug      660

uuaugaggau caucaacgag ccuacggcag cugcuauugc uuauggccug gauaagaggg      720

agggggagaa gaacauccug guguuugacc uggguggcgg aaccuucgau gugucucuuc      780

ucaccauuga caaugguguc uucgaaguug uggccacuaa uggagauacu caucugggug      840

gagaagacuu ugaccagcgu gucauggaac acuucaucaa acuguacaaa aagaagacgg      900

gcaaagaugu caggaaagac aauagagcug ugcagaaacu ccggcgcgag guagaaaagg      960

ccaaacgggc ccugucuucu cagcaucaag caagaauuga aauugagucc uucuaugaag     1020

gagaagacuu uucugagacc cugacucggg ccaaauuuga agaacucaac auggaucugu     1080

uccggucuac uaugaagccc guccagaaag uguuggaaga uucugauuug aagaagucug     1140

auauugauga aauuguucuu guugguggcu cgacucgaau cccaaagauu cagcaacugg     1200

uuaaagaguu cuucaauggc aaggaaccau cccguggcau aaacccagau gaagcuguag     1260

cguauggugc ugcuguccag gcuggugugc ucucugguga ucaagauaca ggugaccugg     1320

uacugcuuga uguauguccc cuuacacuug guauugaaac ugugggaggu gucaugacca     1380

aacugauucc aaggaacaca guggugccua ccaagaaguc ucagaucuuu ucuacagcuu     1440

cugauaauca accaacuguu acaaucaagg ucuaugaagg ugaaagaccc cugacaaaag     1500

acaaucaucu ucuggguaca uuugaucuga cuggaauccc uccugcuccu cguggggucc     1560

cacagauuga agucaccuuu gagauagaug ugaaugguau ucuucgagug acagcugaag     1620

acaaggguac agggaacaaa aauaagauca caaucaccaa ugaccagaau cgccugacac     1680

cugaagaaau cgaaaggaug guuaaugaug cugagaaguu ugcugaggaa gacaaaaagc     1740

ucaaggagcg cauugauacu agaaaugagu uggaaagcua ugccuauucu cuaaagaauc     1800

agauuggaga uaaagaaaag cugggaggua aacuuuccuc ugaagauaag gagaccaugg     1860

aaaaagcugu agaagaaaag auugaauggc uggaaagcca ccaagaugcu gacauugaag     1920

acuucaaagc uaagaagaag gaacuggaag aaauuguuca accaauuauc agcaaacucu     1980

auggaagugc aggcccuccc ccaacuggug aagaggauac agcagaaaaa gaugaguugu     2040

agggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  6186
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (wt)

<400>  6186
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccac gggagcucgc ggugggcauc gaccugggca      120

ccaccuacuc gugcgugggc guguuucagc agggccgcgu ggagauccug gccaacgacc      180

agggcaaccg caccacgccc agcuacgugg ccuucaccga caccgagcgg cuggucgggg      240

acgcggccaa gagccaggcg gcccugaacc cccacaacac cguguucgau gccaagcggc      300

ugaucgggcg caaguucgcg gacaccacgg ugcagucgga caugaagcac uggcccuucc      360

ggguggugag cgagggcggc aagcccaagg ugcgcguaug cuaccgcggg gaggacaaga      420

cguucuaccc cgaggagauc ucguccaugg ugcugagcaa gaugaaggag acggccgagg      480

cguaccuggg ccagcccgug aagcacgcag ugaucaccgu gcccgccuau uucaaugacu      540

cgcagcgcca ggccaccaag gacgcggggg ccaucgcggg gcucaacgug uugcggauca      600

ucaaugagcc cacggcagcu gccaucgccu augggcugga ccggcggggc gcgggagagc      660

gcaacgugcu cauuuuugac cugggugggg gcaccuucga ugugucgguu cucuccauug      720

acgcuggugu cuuugaggug aaagccacug cuggagauac ccaccuggga ggagaggacu      780

ucgacaaccg gcucgugaac cacuucaugg aagaguuccg gcggaagcau gggaaggacc      840

ugagcgggaa caagcgugcc cugcgcaggc ugcgcacagc cugugagcgc gccaagcgca      900

cccuguccuc cagcacccag gccacccugg agauagacuc ccuguucgag ggcguggacu      960

ucuacacguc caucacucgu gcccgcuuug aggaacugug cucagaccuc uuccgcagca     1020

cccuggagcc gguggagaag gcccugcggg augccaagcu ggacaaggcc cagauucaug     1080

acgucguccu gguggggggc uccacacgca uccccaaggu gcagaaguug cugcaggacu     1140

ucuucaacgg caaggagcug aacaagagca ucaacccuga ugaggcugug gccuaugggg     1200

cugcugugca ggcggccgug uugauggggg acaaauguga gaaagugcag gaucuccugc     1260

ugcuggaugu ggcuccccug ucucuggggc uggagacagc aggaggggug augaccacgc     1320

ugauccagag gaacgccacu auccccacca agcagaccca gacuuucacc accuacucgg     1380

acaaccagcc uggggucuuc auccaggugu augaggguga gagggccaug accaaggaca     1440

acaaccugcu ggggcguuuu gaacucagug gcaucccucc ugccccacgu ggaguccccc     1500

agauagaggu gacuuuugac auugaugcua auggcauccu gagcgugaca gccacugaca     1560

ggagcacagg uaaggcuaac aagaucacca ucaccaauga caagggccgg cugagcaagg     1620

aggaggugga gaggaugguu caugaagccg agcaguacaa ggcugaggau gaggcccaga     1680

gggacagagu ggcugccaaa aacucgcugg aggcccaugu cuuccaugug aaagguucuu     1740

ugcaagagga aagccuuagg gacaagauuc ccgaagagga caggcgcaaa augcaagaca     1800

agugucggga aguccuugcc uggcuggagc acaaccagcu ggcagagaag gaggaguaug     1860

agcaucagaa gagggagcug gagcaaaucu gucgccccau cuucuccagg cucuaugggg     1920

ggccuggugu cccugggggc agcaguugug gcacucaagc ccgccagggg gaccccagca     1980

ccggccccau cauugaggag guugauugag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  6187
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (wt)

<400>  6187
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccac gggagcucgc ggugggcauc gaccugggca      120

ccaccuacuc gugcgugggc guguuucagc agggccgcgu ggagauccug gccaacgacc      180

agggcaaccg caccacgccc agcuacgugg ccuucaccga caccgagcgg cuggucgggg      240

acgcggccaa gagccaggcg gcccugaacc cccacaacac cguguucgau gccaagcggc      300

ugaucgggcg caaguucgcg gacaccacgg ugcagucgga caugaagcac uggcccuucc      360

agguggugag cgagggcggc aagcccaagg ugcgcguaug cuaccgcggg gaggacaaga      420

cguucuaccc cgaggagauc ucguccaugg ugcugagcaa gaugaaggag acggccgagg      480

cguaccuggg ccagcccgug aagcacgcag ugaucaccgu gcccaccuau uucaguaacu      540

cgcagcgcca ggccaccaag gacgcggggg ccaucgcggg gcucaaggug cugccgauca      600

ucaaugaggc cacggcagca gccaucgccu augggcugga ccggcggggc gcgggaaagc      660

gcaacgugcu cauuuuugac cugggugggg gcaccuucga ugugucgguu cucuccauug      720

acgccggugu cuuugaggug aaagccacug cuggagauac ccaccuggga ggagaggacu      780

ucgacaaccg gcucgugaac cacuucaugg aagaguuccg gcggaagcau gggaaggacc      840

ugagcgggaa caagcgugcc cugcgcaggc ugcgcacagc cugugagcgc gccaagcgca      900

ccccguccuc cagcacccag gccacccugg agauagacuc ccuguucgag ggcguggacu      960

ucuacaaguc caucacucgu gcccgcuuug aggaacugug cucagaccuc uuccgcagca     1020

cccuggagcc gguggagaag gcccugcggg augccaagcu ggacaaggcc cagauucaug     1080

acuucguccu ggggggaggg cuccacucgc auccccaagg ugcagaaguu gcugcaggac     1140

uucuucaacg gcaaggagcu gaacaagagc aucaacccug aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  6188
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (wt)

<400>  6188
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccaagggac cugcaguugg uauugaucuu ggcaccaccu      120

acucuugugu ggguguuuuc cagcacggaa aagucgagau aauugccaau gaucagggaa      180

accgaaccac uccaagcuau gucgccuuua cggacacuga acgguugauc ggugaugccg      240

caaagaauca aguugcaaug aaccccacca acacaguuuu ugaugccaaa cgucugauug      300

gacgcagauu ugaugaugcu guuguccagu cugauaugaa acauuggccc uuuauggugg      360

ugaaugaugc uggcaggccc aagguccaag uagaauacaa gggagagacc aagagcuucu      420

auccagagga ggugucuucu augguucuga caaagaugaa ggaaauugca gaagccuacc      480

uugggaagac uguuaccaau gcugugguca cagugccagc uuacuuuaau gacucucagc      540

gucaggcuac caaagaugcu ggaacuauug cuggucucaa uguacuuaga auuauuaaug      600

agccaacugc ugcugcuauu gcuuacggcu uagacaaaaa gguuggagca gaaagaaacg      660

ugcucaucuu ugaccuggga gguggcacuu uugauguguc aauccucacu auugaggaug      720

gaaucuuuga ggucaagucu acagcuggag acacccacuu ggguggagaa gauuuugaca      780

accgaauggu caaccauuuu auugcugagu uuaagcgcaa gcauaagaag gacaucagug      840

agaacaagag agcuguaaga cgccuccgua cugcuuguga acgugcuaag cguacccucu      900

cuuccagcac ccaggccagu auugagaucg auucucucua ugaaggaauc gacuucuaua      960

ccuccauuac ccgugcccga uuugaagaac ugaaugcuga ccuguuccgu ggcacccugg     1020

acccaguaga gaaagcccuu cgagaugcca aacuagacaa gucacagauu caugauauug     1080

uccugguugg ugguucuacu cguaucccca agauucagaa gcugcuccaa gacuucuuca     1140

auggaaaaga acugaauaag agcaucaacc cugaugaagc uguugcuuau ggugcagcug     1200

uccaggcagc caucuugucu ggagacaagu cugagaaugu ucaagauuug cugcucuugg     1260

augucacucc ucuuucccuu gguauugaaa cugcuggugg agucaugacu guccucauca     1320

agcguaauac caccauuccu accaagcaga cacagaccuu cacuaccuau ucugacaacc     1380

agccuggugu gcuuauucag guuuaugaag gcgagcgugc caugacaaag gauaacaacc     1440

ugcuuggcaa guuugaacuc acaggcauac cuccugcacc ccgagguguu ccucagauug     1500

aagucacuuu ugacauugau gccaauggua uacucaaugu cucugcugug gacaagagua     1560

cgggaaaaga gaacaagauu acuaucacua augacaaggg ccguuugagc aaggaagaca     1620

uugaacguau gguccaggaa gcugagaagu acaaagcuga agaugagaag cagagggaca     1680

aggugucauc caagaacuca cuugaguccu augccuucaa caugaaagca acuguugaag     1740

augagaaacu ucaaggcaag auuaacgaug aggacaaaca gaagauucug gacaagugua     1800

augaaauuau caacuggcuu gauaagaauc agacugcuga gaaggaagaa uuugaacauc     1860

aacagaaaga gcuggagaaa guuugcaacc ccaucaucac caagcuguac cagagugcag     1920

gaggcaugcc aggaggaaug ccugggggau uuccuggugg uggagcuccu cccucuggug     1980

gugcuuccuc agggcccacc auugaagagg uugauuaagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  6189
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (wt)

<400>  6189
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaagugcca gccgagcugc agcagcccgu cucgugggcg      120

ccgcagccuc ccggggcccu acggccgccc gccaccagga uagcuggaau ggccuuaguc      180

augaggcuuu uagacuuguu ucaaggcggg auuaugcauc agaagcaauc aagggagcag      240

uuguugguau ugauuugggu acuaccaacu ccugcguggc aguuauggaa gguaaacaag      300

caaaggugcu ggagaaugcc gaaggugcca gaaccacccc uucaguugug gccuuuacag      360

cagaugguga gcgacuuguu ggaaugccgg ccaagcgaca ggcugucacc aacccaaaca      420

auacauuuua ugcuaccaag cgucucauug gccggcgaua ugaugauccu gaaguacaga      480

aagacauuaa aaauguuccc uuuaaaauug uccgugccuc caauggugau gccuggguug      540

aggcucaugg gaaauuguau ucuccgaguc agauuggagc auuuguguug augaagauga      600

aagagacugc agaaaauuac uuggggcaca cagcaaaaaa ugcugugauc acagucccag      660

cuuauuucaa ugacucgcag agacaggcca cuaaagaugc uggccagaua ucuggacuga      720

augugcuucg ggugauuaau gagcccacag cugcugcucu ugccuauggu cuagacaaau      780

cagaagacaa agucauugcu guauaugauu uagguggugg aacuuuugau auuucuaucc      840

uggaaauuca gaaaggagua uuugagguga aauccacaaa uggggauacc uucuuaggug      900

gggaagacuu ugaccaggcc uugcuacggc acauugugaa ggaguucaag agagagacag      960

ggguugauuu gacuaaagac aacauggcac uucagagggu acgggaagcu gcugaaaagg     1020

cuaaauguga acucuccuca ucugugcaga cugacaucaa uuugcccuau cuuacaaugg     1080

auucuucugg acccaagcau uugaauauga aguugacccg ugcucaauuu gaagggauug     1140

ucacugaucu aaucagaagg acuaucgcuc caugccaaaa agcuaugcaa gaugcagaag     1200

ucagcaagag ugacauagga gaagugauuc uugugggugg caugacuagg augcccaagg     1260

uucagcagac uguacaggau cuuuuuggca gagccccaag uaaagcuguc aauccugaug     1320

aggcuguggc cauuggagcu gccauucagg gagguguguu ggccggcgau gucacggaug     1380

ugcugcuccu ugaugucacu ccccugucuc uggguauuga aacucuagga ggugucuuua     1440

ccaaacuuau uaauaggaau accacuauuc caaccaagaa aagccaggua uucucuacug     1500

ccgcugaugg ucaaacgcaa guggaaauua aaguguguca gggugaaaga gagauggcug     1560

gagacaacaa acuccuugga caguuuacuu ugauuggaau cccaccagcc ccucguggag     1620

uuccucagau ugaaguuaca uuugacauug augccaaugg gauaguacau guuucugcua     1680

aagauaaagg cacaggacgu gagcagcaga uuguaaucca gucuucuggu ggauuaagca     1740

aagaugauau ugaaaauaug guuaaaaaug cagagaaaua ugcugaagaa gaccggcgaa     1800

agaaggaacg aguugaagca guuaauaugg cugaaggaau cauucacgac acagaaacca     1860

agauggaaga guucaaggac caauuaccug cugaugagug caacaagcug aaagaagaga     1920

uuuccaaaau gagggagcuc cuggcuagaa aagacagcga aacaggagaa aauauuagac     1980

aggcagcauc cucucuucag caggcaucac ugaagcuguu cgaaauggca uacaaaaaga     2040

uggcaucuga gcgagaaggc ucuggaaguu cuggcacugg ggaacaaaag gaagaucaaa     2100

aggaggaaaa acaguaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  6190
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (wt)

<400>  6190
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuggcugucc cggagauggg ccugcagggg cuguacaucg      120

gcuccagccc ggagcggucc ccagugccua gcccacccgg cuccccgagg acccaggaaa      180

gcugcggcau ugccccccuc acacccucgc agucuccaaa acccgagguc cgagcccccc      240

agcaggccuc cuucucugug gugguggcca uugacuucgg caccacgucu aguggcuaug      300

cuuucagcuu ugccagugac ccugaggcca uccacaugau gaggaaaugg gagggcggag      360

acccgggcgu ggcccaccag aagaccccga ccugccugcu gcugacuccg gagggcgccu      420

uccacagcuu uggcuacacc gcccgcgauu acuaccauga ccuggacccc gaagaggcgc      480

gggacuggcu cuacuucgag aaguucaaga ugaagaucca cagcgccacg gaucucaccu      540

ugaagaccca gcuagaggca guaaauggaa agacgaugcc cgcccuggag guguucgccc      600

augcccugcg cuucuucagg gagcacgccc uucaggagcu gagggagcag agcccaucgc      660

ugccagagaa ggacacugug cgcugggugu ugacggugcc ugccaucugg aaacagccag      720

ccaagcaguu caugcgggag gcugccuacc uggcuggacu ugugucccga gagaaugcag      780

agcagcuacu caucgcccug gagcccgagg ccgccucggu auacugccgc aagcugcgcc      840

ugcaccagcu ccuggaccug aguggccggg ccccaggugg ugggcgccug ggugagcgcc      900

gcuccaucga cuccagcuuc cgucaggcuc gggagcagcu gcgaaggucc cgccacagcc      960

gcacguuccu gguggaguca ggcguaggag agcugugggc agagaugcaa gcaggagacc     1020

gcuacguggu ggccgacugc ggcggaggca ccguggaccu gacggugcac cagcuggagc     1080

agccccaugg cacccucaag gagcucuaca aggcaucugg gggcccuuau ggcgcggugg     1140

gcguggaccu ggccuucgag cagcugcugu gccgcaucuu cggcgaggac uucaucgcca     1200

ccuucaaaag gcaacggccg gcagccuggg uagaucugac caucgccuuc gaggcucgca     1260

agcgcacugc uggcccacac cgugcagggg cgcucaacau cucgcugccc uucuccuuca     1320

uugacuucua ccgcaagcag cggggccaca acguggagac cgcucugcgc aggagcagcg     1380

ugaacuucgu gaaguggucc ucacagggga ugcuccgaau gucuugugaa gccaugaacg     1440

agcucuuuca gcccaccguc agcgggauca uccagcacau agaggcccug cuggcacggc     1500

cggaggugca gggugugaag cugcuguucc uagugggcgg cuucgccgag ucagcggugc     1560

ugcagcacgc ggugcaggcg gcgcugggcg cccgcggucu gcgugucgug gucccgcacg     1620

acgugggccu caccauccuc aaaggcgcgg ugcuguucgg ccaggcgccg ggcguggugc     1680

ggguccgccg cucgccgcuc accuauggcg ugggcgugcu caaccgcuuu gugccugggc     1740

gccacccgcc cgaaaagcug cugguucgcg acggccgccg cuggugcacc gacgucuucg     1800

agcgcuucgu ggccgccgag cagucggugg cccugggcga ggaggugcgg cgcagcuacu     1860

gcccggcgcg ucccggccag cggcgcguac ucaucaaccu guacugcugc gcggcagagg     1920

augcgcgcuu caucaccgac cccggcgugc gcaaaugcgg cgcgcucagc cucgagcuug     1980

agcccgccga cugcggccag gacaccgccg gcgcgccucc cggccgccgc gagauccgcg     2040

ccgccaugca guuuggcgac accgaaauua aggucaccgc cgucgacguc agcaccaauc     2100

gcuccgugcg cgcguccauc gacuuucuuu ccaacugagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  6191
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (wt)

<400>  6191
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcggccaucg gaguucaccu gggcugcacc ucagccugug      120

uggccgucua uaaggauggc cgggcuggug ugguugcaaa ugaugccggu gaccgaguua      180

cuccagcugu uguugcuuac ucagaaaaug aagagauugu uggauuggca gcaaaacaaa      240

guagaauaag aaauauuuca aauacaguaa ugaaaguaaa gcagauccug ggcagaagcu      300

ccagugaucc acaagcucag aaauacaucg cggaaaguaa auguuuaguc auugaaaaaa      360

augggaaauu acgauaugaa auagauacug gagaagaaac aaaauuuguu aacccagaag      420

auguugccag acugauauuu aguaaaauga aagaaacggc acauucugua uugggcucag      480

augcaaauga uguaguuauu acugucccgu uugauuuugg agaaaagcaa aaaaaugcuc      540

uuggagaagc agcuagagcu gcuggauuua auguuuugcg auuaauucac gaaccgucug      600

cagcucugcu ugcuuaugga auuggacaag acuccccuac uggaaaaagc aauauuuugg      660

uguuuaagcu gggaggaaca uccuuaucuc ucagcgucau ggaaguuaac aguggaauau      720

aucggguucu uucaacaaac acugaugaua acaucggugg ugcacauuuc acagaaaccu      780

uagcacagua ucuagcuucu gaguuccaaa gauccuucaa acaugaugug agaggaaaug      840

cgcgagccau gaugaaauua acgaacagug cugaaguagc gaaacauucu uugucaaccu      900

ugggaagugc caacuguuuu cuugacucau uauaugaagg ucaagauuuu gauugcaaug      960

uguccagagc aagauuugaa cuucuuuguu cuccacuuuu uaauaagugu auagaagcaa     1020

ucagaggacu cuuagaucaa aauggauuua cagcagauga uaucaacaag guuguccuuu     1080

guggaggguc uucucgaauc ccaaagcuac agcaacugau uaaagaucuu uucccagcug     1140

uugagcuucu caauucuauc ccuccugaug aagugauccc uauuggugca gcuauagaag     1200

caggaauccu uauugggaaa gaaaaccugu ugguggaaga cucucuuaug auagaguguu     1260

cagccagaga uauuuuaguu aagggugugg acgaaucagg agccaguaga uucacagugc     1320

uguuuccauc agggacuccu uugccagcuc gaagacaaca cacauugcaa gccccuggaa     1380

gcauaucuuc agugugccuu gaacucuaug agucugaugg gaagaacucu gccaaagagg     1440

aaaccaaguu ugcacagguu guacuccagg auuuagauaa aaaagaaaau ggauuacgug     1500

auauauuagc uguucuuacu augaaaaggg auggaucuuu acaugugaca ugcacagauc     1560

aagaaacugg aaaaugugaa gcaaucucua uugagauagc aucuuaggga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  6192
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (wt)

<400>  6192
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucgguggugg gguuggacgu gggcucgcag agcugcuaca      120

ucgcgguagc ccgggccggg ggcaucgaga ccaucgccaa ugaguucagc gaccggugca      180

ccccgucagu cauaucauuu ggaucaaaaa auagaacaau cggaguugca gccaaaaauc      240

agcaaaucac ucaugcaaac aauacggugu cuaacuucaa aagauuucau ggccgagcau      300

ucaaugaccc cuucauucaa aaggagaagg aaaacuugag uuacgauuug guuccauuga      360

aaaauggugg aguuggaaua aagguaaugu acauggguga agaacaucua uuuagugugg      420

agcagauaac agccauguug uugacuaagc ugaaggaaac ugcugaaaac agccucaaga      480

aaccaguaac agauuguguu auuucagucc ccuccuucuu uacagaugcu gagaggcgau      540

cuguguuaga ugcugcacag auuguuggcc uaaacuguuu aagacuuaug aaugacauga      600

cagcuguugc uuugaauuac ggaauuuaua agcaggaucu cccaagccug gaugagaaac      660

cucggauagu gguuuuuguu gauaugggac auucagcuuu ucaagugucu gcuugugcuu      720

uuaacaaggg aaaauugaag guacugggaa cagcuuuuga uccuuucuua ggaggaaaaa      780

acuucgauga aaaguuagug gaacauuuuu gugcagaauu uaaaacuaag uacaaguugg      840

augcaaaauc caaaauacga gcacuccuac gucuguauca ggaaugugaa aaacugaaaa      900

agcuaaugag cucuaacagc acagaccuuc cacugaauau cgaaugcuuu augaaugaua      960

aagauguuuc cggaaagaug aacaggucac aauuugaaga acucugugcu gaacuucugc     1020

aaaagauaga aguaccccuu uauucacugu uggaacaaac ucaucucaaa guagaagaug     1080

ugagugcagu ugagauuguu ggaggcgcua cacgaauccc agcugugaag gaaagaauug     1140

ccaaauucuu uggaaaagau auuagcacaa cacucaaugc agaugaagca guagccagag     1200

gaugugcauu acagugugca auacuuuccc cggcauuuaa aguuagagaa uuuuccguca     1260

cagaugcagu uccuuuucca auaucucuga ucuggaacca ugauucagaa gauacugaag     1320

guguucauga agucuuuagu cgaaaccaug cugcuccuuu cuccaaaguu cucaccuuuc     1380

ugagaagggg gccuuuugag cuagaagcau ucuauucuga uccccaagga guuccauauc     1440

cagaagcaaa aauaggccgc uuuguaguuc agaauguuuc ugcacagaaa gauggagaaa     1500

aaucuagagu aaaagucaaa gugcgaguca acacccaugg cauuuucacc aucucuacgg     1560

caucuauggu ggagaaaguc ccaacugagg agaaugaaau gucuucugaa gcugacaugg     1620

agugucugaa ucagagacca ccagaaaacc cagacacuga uaaaaauguc cagcaagaca     1680

acagugaagc uggaacacag ccccagguac aaacugaugc ucaacaaacc ucacagucuc     1740

ccccuucacc ugaacuuacc ucagaagaaa acaaaauccc agaugcugac aaagcaaaug     1800

aaaaaaaagu ugaccagccu ccagaagcua aaaagcccaa aauaaaggug gugaauguug     1860

agcugccuau ugaagccaac uuggucuggc aguuagggaa agaccuucuu aacauguaua     1920

uugagacaga ggguaagaug auaaugcaag auaaauugga aaaagaaagg aaugaugcua     1980

aaaaugcagu ugaggaauau guguaugagu ucagagacaa gcugugugga ccauaugaaa     2040

aauuuauaug ugagcaggau caucaaaauu uuuugagacu ccucacagaa acugaagacu     2100

ggcuguauga agaaggagag gaccaagcua aacaagcaua uguugacaag uuggaagaau     2160

uaaugaaaau uggcacucca guuaaaguuc gguuucagga agcugaagaa cggccaaaaa     2220

uguuugaaga acuaggacag aggcugcagc auuaugccaa gauagcagcu gacuucagaa     2280

auaaggauga gaaauacaac cauauugaug agucugaaau gaaaaaagug gagaagucug     2340

uuaaugaagu gauggaaugg augaauaaug ucaugaaugc ucaggcuaaa aagagucuug     2400

aucaggaucc aguuguacgu gcucaggaaa uuaaaacaaa aaucaaggaa uugaacaaca     2460

caugugaacc cguuguaaca caaccgaaac caaaaauuga aucacccaaa cuggaaagaa     2520

cuccaaaugg cccaaauauu gauaaaaagg aagaagauuu agaagacaaa aacaauuuug     2580

gugcugaacc uccacaucag aauggugaau guuacccuaa ugagaaaaau ucuguuaaua     2640

uggacuugga cuagggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  6193
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (wt)

<400>  6193
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagacaaag uuaggaggca gaggccgagg aggcgagucu      120

guugggccuu gguggcugug cucuuggcag accuguuggc acugagugau acacuggcag      180

ugaugucugu ggaccugggc agugagucca ugaagguggc cauugucaaa ccuggagugc      240

ccauggaaau ugucuugaau aaggaaucuc ggaggaaaac accggugauc gugacccuga      300

aagaaaauga aagauucuuu ggagacagug cagcaagcau ggcgauuaag aauccaaagg      360

cuacgcuacg uuacuuccag caccuccugg ggaagcaggc agauaacccc cauguagcuc      420

uuuaccaggc ccgcuucccg gagcacgagc ugacuuucga cccacagagg cagacugugc      480

acuuucagau cagcucgcag cugcaguucu caccugagga aguguugggc augguucuca      540

auuauucucg uucucuagcu gaagauuuug cagagcagcc caucaaggau gcagugauca      600

ccgugccagu cuucuucaac caggccgagc gccgagcugu gcugcaggcu gcucguaugg      660

cuggccucaa agugcugcag cucaucaaug acaacaccgc cacugcccuc agcuauggug      720

ucuuccgccg gaaagauauu aacaccacug cccagaauau cauguucuau gacaugggcu      780

caggcagcac cguaugcacc auugugaccu accagauggu gaagacuaag gaagcuggga      840

ugcagccaca gcugcagauc cggggaguag gauuugaccg uacccugggg ggccuggaga      900

uggagcuccg gcuucgagaa cgccuggcug ggcuuuucaa ugagcagcgc aagggucaga      960

gagcaaagga ugugcgggag aacccgcgug ccauggccaa gcugcugcgu gaggcuaauc     1020

ggcucaaaac cguccucagu gccaacgcug accacauggc acagauugaa ggccugaugg     1080

augaugugga cuucaaggca aaagugacuc guguggaauu ugaggaguug ugugcagacu     1140

uguuugagcg ggugccuggg ccuguacagc aggcccucca gagugccgaa augagucugg     1200

augagauuga gcaggucauc cuggugggug gggccacucg gguccccaga guucaggagg     1260

ugcugcugaa ggccgugggc aaggaggagc uggggaagaa caucaaugca gaugaagcag     1320

ccgccauggg ggcaguguac caggcagcug cgcucagcaa agccuuuaaa gugaagccau     1380

uugucguccg agaugcagug gucuacccca uccuggugga guucacgagg gagguggagg     1440

aggagccugg gauucacagc cugaagcaca auaaacgggu acucuucucu cggauggggc     1500

ccuacccuca acgcaaaguc aucaccuuua accgcuacag ccaugauuuc aacuuccaca     1560

ucaacuacgg cgaccugggc uuccuggggc cugaagaucu ucggguauuu ggcucccaga     1620

aucugaccac agugaagcua aaaggggugg gugacagcuu caagaaguau ccugacuacg     1680

aguccaaggg caucaaggcu cacuucaacc uggaugagag uggcgugcuc agucuagaca     1740

ggguggaguc uguauuugag acacugguag aggacagcgc agaagaggaa ucuacucuca     1800

ccaaacuugg caacaccauu uccagccugu uuggaggcgg uaccacacca gaugccaagg     1860

agaaugguac ugauacuguc caggaggaag aggagagccc ugcagagggg agcaaggacg     1920

agccugggga gcaggucgag cucaaggagg aagcugaggc cccaguggag gauggcucuc     1980

agcccccacc cccugaaccu aagggagaug caaccccuga gggagaaaag gccacagaaa     2040

aagaaaaugg ggacaagucu gaggcccaga aaccaaguga gaaggcagag gcagggccug     2100

agggcgucgc uccagcccca gagggagaga agaagcagaa gcccgccagg aagcggcgaa     2160

ugguagagga gaucggggug gagcugguug uucuggaccu gccugacuug ccagaggaua     2220

agcuggcuca gucggugcag aaacuucagg acuugacacu ccgagaccug gagaagcagg     2280

aacgggaaaa agcugccaac agcuuggaag cauucauauu ugagacccag gacaagcugu     2340

accagcccga guaccaggaa guguccacag aggagcagcg ugaggagauc ucugggaagc     2400

ucagcgccgc auccaccugg cuggaggaug aggguguugg agccaccaca gugauguuga     2460

aggagaagcu ggcugagcug aggaagcugu gccaagggcu guuuuuucgg guagaggagc     2520

gcaagaagug gcccgaacgg cugucugccc ucgauaaucu ccucaaccau uccagcaugu     2580

uccucaaggg ggcccggcuc aucccagaga uggaccagau cuucacugag guggagauga     2640

caacguuaga gaaagucauc aaugagaccu gggccuggaa gaaugcaacu cuggccgagc     2700

aggcuaagcu gcccgccaca gagaagccug uguugcucuc aaaagacauu gaagcuaaga     2760

ugauggcccu ggaccgagag gugcaguauc ugcucaauaa ggccaaguuu accaagcccc     2820

ggccccggcc uaaggacaag aaugggaccc gggcagagcc accccucaau gccagugcca     2880

gugaccaggg ggagaagguc aucccuccag caggccagac ugaagaugca gagcccauuu     2940

cagaaccuga gaaaguagag acuggauccg agccaggaga cacugagccu uuggaguuag     3000

gagguccugg agcagaaccu gaacagaaag aacaaucgac aggacagaag cggccuuuga     3060

agaacgacga acuauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6194
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (wt)

<400>  6194
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccugaggaaa cccagaccca agaccaaccg auggaggagg      120

aggagguuga gacguucgcc uuucaggcag aaauugccca guugauguca uugaucauca      180

auacuuucua cucgaacaaa gagaucuuuc ugagagagcu cauuucaaau ucaucagaug      240

cauuggacaa aauccgguau gagagcuuga cagaucccag uaaauuagac ucugggaaag      300

agcugcauau uaaccuuaua ccgaacaaac aagaucgaac ucucacuauu guggauacug      360

gaauuggaau gaccaaggcu gacuugauca auaaccuugg uacuaucgcc aagucuggga      420

ccaaagcguu cauggaagca uugcaggcug gugcagauau cucuaugauu ggccaguucg      480

guguugguuu uuauucugcu uauuugguug cugagaaagu aacugugauc accaaacaua      540

acgaugauga gcaguacgcu ugggaguccu cagcaggggg aucauucaca gugaggacag      600

acacagguga accuaugggu cguggaacaa aaguuauccu acaccugaaa gaagaccaaa      660

cugaguacuu ggaggaacga agaauaaagg agauugugaa gaaacauucu caguuuauug      720

gauaucccau uacucuuuuu guggagaagg aacgugauaa agaaguaagc gaugaugagg      780

cugaagaaaa ggaagacaaa gaagaagaaa aagaaaaaga agagaaagag ucggaagaca      840

aaccugaaau ugaagauguu gguucugaug aggaagaaga aaagaaggau ggugacaaga      900

agaagaagaa gaagauuaag gaaaaguaca ucgaucaaga agaacucaac aaaacaaagc      960

ccaucuggac cagaaauccc gacgauauua cuaaugagga guacggagag uucuauaaga     1020

gcuugaccaa ugacugggaa gaucacuugg cagugaagca uuuuucaguu gaaggacagu     1080

uggaguucag agcccuucua uuugucccac gacgugcucc uuuugaucug uuugaaaaca     1140

gaaagaaaaa gaacaacauc aaauuguaug uacgcagagu uuucaucaug gauaacugug     1200

aggagcuaau cccugaauau cugaacuuca uuagaggggu gguagacucg gaggaucucc     1260

cucuaaacau aucccgugag auguugcaac aaagcaaaau uuugaaaguu aucaggaaga     1320

auuuggucaa aaaaugcuua gaacucuuua cugaacuggc ggaagauaaa gagaacuaca     1380

agaaauucua ugagcaguuc ucuaaaaaca uaaagcucgg aauacacgaa gacucucaaa     1440

aucggaagaa gcucucagag cuguuaaggu acuacacauc ugccucuggu gaugagaugg     1500

uuucucucaa ggacuacugc accagaauga aggagaacca gaaacauauc uauuauauca     1560

caggugagac caaggaccag guagcuaacu cagccuuugu ggaacgucuu cggaaacaug     1620

gcuuagaagu gaucuauaug auugagccca uugaugagua cuguguccaa cagcugaagg     1680

aauuugaggg gaagacuuua gugucaguca ccaaagaagg ccuggaacuu ccagaggaug     1740

aagaagagaa aaagaagcag gaagagaaaa aaacaaaguu ugagaaccuc ugcaaaauca     1800

ugaaagacau auuggagaaa aaaguugaaa aggugguugu gucaaaccga uuggugacau     1860

cuccaugcug uauugucaca agcacauaug gcuggacagc aaacauggag agaaucauga     1920

aagcucaagc ccuaagagac aacucaacaa uggguuacau ggcagcaaag aaacaccugg     1980

agauaaaccc ugaccauucc auuauugaga ccuuaaggca aaaggcagag gcugauaaga     2040

acgacaaguc ugugaaggau cuggucaucu ugcuuuauga aacugcgcuc cugucuucug     2100

gcuucagucu ggaagauccc cagacacaug cuaacaggau cuacaggaug aucaaacuug     2160

gucuggguau ugaugaagau gacccuacug cugaugauac cagugcugcu guaacugaag     2220

aaaugccacc ccuugaagga gaugacgaca caucacgcau ggaagaagua gacuaaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  6195
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (wt)

<400>  6195
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gauuccagua aauuagacuc ugggaaaggg cugcauauua      120

accuuguacc aaacaaacaa aaucaaaccc ucacuauugu ggacacuaga auuggaauga      180

ccaagacuga cuugaucaau aaccucggua cugucaccaa gucugggacc aaagcauuca      240

uggaagcauu gcaggcugau gcagauaucu cuaugauugg ccauuucggg guugguuuuu      300

auucugcuua uuugguugcc aagaaaguaa cugugaucag caaacauaac aaugaugagc      360

aguacaccug ggaguccuca gcagggggau cauucacagu gaggacagac gagugaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  6196
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (wt)

<400>  6196
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccugaggaag ugcaccaugg agaggaggag guggagacuu      120

uugccuuuca ggcagaaauu gcccaacuca ugucccucau caucaauacc uucuauucca      180

acaaggagau uuuccuucgg gaguugaucu cuaaugcuuc ugaugccuug gacaagauuc      240

gcuaugagag ccugacagac ccuucgaagu uggacagugg uaaagagcug aaaauugaca      300

ucauccccaa cccucaggaa cguacccuga cuuugguaga cacaggcauu ggcaugacca      360

aagcugaucu cauaaauaau uugggaacca uugccaaguc ugguacuaaa gcauucaugg      420

aggcucugca ggcuggugca gacaucucca ugauugggca guuugguguu ggcuuuuauu      480

cugccuacuu gguggcagag aaagugguug ugaucacaaa gcacaacgau gaugaacagu      540

augcuuggga gucuucugcu ggagguuccu ucacugugcg ugcugaccau ggugagccca      600

uuggcagggg uaccaaagug auccuccauc uuaaagaaga ucagacagag uaccuagaag      660

agaggcgggu caaagaagua gugaagaagc auucucaguu cauaggcuau cccaucaccc      720

uuuauuugga gaaggaacga gagaaggaaa uuagugauga ugaggcagag gaagagaaag      780

gugagaaaga agaggaagau aaagaugaug aagaaaaacc caagaucgaa gauguggguu      840

cagaugagga ggaugacagc gguaaggaua agaagaagaa aacuaagaag aucaaagaga      900

aauacauuga ucaggaagaa cuaaacaaga ccaagccuau uuggaccaga aacccugaug      960

acaucaccca agaggaguau ggagaguucu acaagagccu cacuaaugac ugggaagacc     1020

acuuggcagu caagcacuuu ucuguagaag gucaguugga guucagggca uugcuauuua     1080

uuccucgucg ggcucccuuu gaccuuuuug agaacaagaa gaaaaagaac aacaucaaac     1140

ucuauguccg ccguguguuc aucauggaca gcugugauga guugauacca gaguaucuca     1200

auuuuauccg uggugugguu gacucugagg aucugccccu gaacaucucc cgagaaaugc     1260

uccagcagag caaaaucuug aaagucauuc gcaaaaacau uguuaagaag ugccuugagc     1320

uguucucuga gcuggcagaa gacaaggaga auuacaagaa auucuaugag gcauucucua     1380

aaaaucucaa gcucggaauc cacgaagacu ccacuaaccg ccgccgccug ucugagcugc     1440

ugcgcuauca uaccucccag ucuggagaug agaugacauc ucugucagag uauguuucuc     1500

gcaugaagga gacacagaag uccaucuauu acaucacugg ugagagcaaa gagcaggucg     1560

ccaacucagc uuuuguggag cgagugcgga aacggggcuu cgagguggua uauaugaccg     1620

agcccauuga cgaguacugu gugcagcagc ucaaggaauu ugaugggaaa agccuggucu     1680

caguuaccaa ggagggucug gagcugccug aggaugagga ggagaagaag aagauggaag     1740

agagcaaggc aaaguuugag aaccucugca agcucaugaa agaaaucuua gauaagaagg     1800

uugagaaggu gacaaucucc aauagacuug ugucuucacc uugcugcauu gugaccagca     1860

ccuacggcug gacagccaau auggagcgga ucaugaaagc ccaggcacuu cgggacaacu     1920

ccaccauggg cuauaugaug gccaaaaagc accuggagau caacccugac caccccauug     1980

uggagacgcu gcggcagaag gcugaggccg acaagaauga uaaggcaguu aaggaccugg     2040

uggugcugcu guuugaaacc gcccugcuau cuucuggcuu uucccuugag gauccccaga     2100

cccacuccaa ccgcaucuau cgcaugauca agcuaggucu agguauugau gaagaugaag     2160

uggcagcaga ggaacccaau gcugcaguuc cugaugagau ccccccucuc gagggcgaug     2220

aggaugcguc ucgcauggaa gaagucgauu agggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  6197
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (wt)

<400>  6197
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agggcccugu gggugcuggg ccucugcugc guccugcuga      120

ccuucggguc ggucagagcu gacgaugaag uugaugugga ugguacagua gaagaggauc      180

uggguaaaag uagagaagga ucaaggacgg augaugaagu aguacagaga gaggaagaag      240

cuauucaguu ggauggauua aaugcaucac aaauaagaga acuuagagag aagucggaaa      300

aguuugccuu ccaagccgaa guuaacagaa ugaugaaacu uaucaucaau ucauuguaua      360

aaaauaaaga gauuuuccug agagaacuga uuucaaaugc uucugaugcu uuagauaaga      420

uaaggcuaau aucacugacu gaugaaaaug cucuuucugg aaaugaggaa cuaacaguca      480

aaauuaagug ugauaaggag aagaaccugc ugcaugucac agacaccggu guaggaauga      540

ccagagaaga guugguuaaa aaccuuggua ccauagccaa aucugggaca agcgaguuuu      600

uaaacaaaau gacugaagca caggaagaug gccagucaac uucugaauug auuggccagu      660

uuggugucgg uuucuauucc gccuuccuug uagcagauaa gguuauuguc acuucaaaac      720

acaacaacga uacccagcac aucugggagu cugacuccaa ugaauuuucu guaauugcug      780

acccaagagg aaacacucua ggacggggaa cgacaauuac ccuugucuua aaagaagaag      840

caucugauua ccuugaauug gauacaauua aaaaucucgu caaaaaauau ucacaguuca      900

uaaacuuucc uauuuaugua uggagcagca agacugaaac uguugaggag cccauggagg      960

aagaagaagc agccaaagaa gagaaagaag aaucugauga ugaagcugca guagaggaag     1020

aagaagaaga aaagaaacca aagacuaaaa aaguugaaaa aacugucugg gacugggaac     1080

uuaugaauga uaucaaacca auauggcaga gaccaucaaa agaaguagaa gaagaugaau     1140

acaaagcauu cuacaaauca uuuucaaagg aaagugauga ccccauggcu uauauucacu     1200

uuacugcuga aggggaaguu accuucaaau caauuuuauu uguacccaca ucugcuccac     1260

guggucuguu ugacgaauau ggaucuaaaa agagcgauua cauuaagcuc uaugugcgcc     1320

guguauucau cacagacgac uuccaugaua ugaugccuaa auaccucaau uuugucaagg     1380

guguggugga cucagaugau cuccccuuga auguuucccg cgagacucuu cagcaacaua     1440

aacugcuuaa ggugauuagg aagaagcugg uucguaaaac gcuggacaug aucaagaaga     1500

uugcugauga uaaauacaau gauacuuuuu ggaaagaauu ugguaccaac aucaagcugg     1560

gugugauuga agaccacucg aaucgaacac gucuugcuaa acuucuuagg uuccagucuu     1620

cucaucaucc aacugacauu acuagccuag accaguaugu ggaaagaaug aaggaaaaac     1680

aagacaaaau cuacuucaug gcugggucca gcagaaaaga ggcugaaucu ucuccauuug     1740

uugagcgacu ucugaaaaag ggcuaugaag uuauuuaccu cacagaaccu guggaugaau     1800

acuguauuca ggcccuuccc gaauuugaug ggaagagguu ccagaauguu gccaaggaag     1860

gagugaaguu cgaugaaagu gagaaaacua aggagagucg ugaagcaguu gagaaagaau     1920

uugagccucu gcugaauugg augaaagaua aagcccuuaa ggacaagauu gaaaaggcug     1980

uggugucuca gcgccugaca gaaucuccgu gugcuuuggu ggccagccag uacggauggu     2040

cuggcaacau ggagagaauc augaaagcac aagcguacca aacgggcaag gacaucucua     2100

caaauuacua ugcgagucag aagaaaacau uugaaauuaa ucccagacac ccgcugauca     2160

gagacaugcu ucgacgaauu aaggaagaug aagaugauaa aacaguuuug gaucuugcug     2220

ugguuuuguu ugaaacagca acgcuucggu caggguaucu uuuaccagac acuaaagcau     2280

auggagauag aauagaaaga augcuucgcc ucaguuugaa cauugacccu gaugcaaagg     2340

uggaagaaga acccgaagaa gaaccugaag agacagcaga agacacaaca gaagacacag     2400

agcaagacga agaugaagaa auggaugugg gaacagauga agaagaagaa acagcaaagg     2460

aaucuacagc ugaaaaagau gaauuguaag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  6198
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (wt)

<400>  6198
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgcgcgagc ugcgggcgcu gcugcugugg ggccgccgcc      120

ugcggccuuu gcugcgggcg ccggcgcugg cggccgugcc gggaggaaaa ccaauucugu      180

guccucggag gaccacagcc caguugggcc ccaggcgaaa cccagccugg agcuugcagg      240

caggacgacu guucagcacg cagaccgccg aggacaagga ggaaccccug cacucgauua      300

ucagcagcac agagagcgug caggguucca cuuccaaaca ugaguuccag gccgagacaa      360

agaagcuguu ggacauuguu gcccgguccc uguacucaga aaaagaggug uuuauacggg      420

agcugaucuc caaugccagc gaugccuugg aaaaacugcg ucacaaacug gugucugacg      480

gccaagcacu gccagaaaug gagauucacu ugcagaccaa ugccgagaaa ggcaccauca      540

ccauccagga uacugguauc gggaugacac aggaagaacu gguguccaac cuggggacga      600

uugccagauc ggggucaaag gccuuccugg augcucugca gaaccaggcu gaggccagca      660

gcaagaucau cggccaguuu ggaguggguu ucuacucagc uuucauggug gcugacagag      720

uggaggucua uucccgcucg gcagccccgg ggagccuggg uuaccagugg cuuucagaug      780

guucuggagu guuugaaauc gccgaagcau cgggaguuag aaccgggaca aaaaucauca      840

uccaccugaa auccgacugc aaggaguuuu ccagcgaggc ccgggugcga gaugugguaa      900

cgaaguacag caacuucguc agcuuccccu uguacuugaa uggaaggcgg augaacaccu      960

ugcaggccau cuggaugaug gaccccaagg auguccguga guggcaacau gaggaguucu     1020

accgcuacgu cgcgcaggcu cacgacaagc cccgcuacac ccugcacuau aagacggacg     1080

caccgcucaa cauccgcagc aucuucuacg ugcccgacau gaaaccgucc auguuugaug     1140

ugagccggga gcugggcucc agcguugcac uguacagccg caaaguccuc auccagacca     1200

aggccacgga cauccugccc aaguggcugc gcuucauccg agguguggug gacagugagg     1260

acauuccccu gaaccucagc cgggagcugc ugcaggagag cgcacucauc aggaaacucc     1320

gggacguuuu acagcagagg cugaucaaau ucuucauuga ccagaguaaa aaagaugcug     1380

agaaguaugc aaaguuuuuu gaagauuacg gccuguucau gcgggagggc auugugaccg     1440

ccaccgagca ggaggucaag gaggacauag caaagcugcu gcgcuacgag uccucggcgc     1500

ugcccuccgg gcagcuaacc agccucucag aauacgccag ccgcaugcgg gccggcaccc     1560

gcaacaucua cuaccugugc gcccccaacc gucaccuggc agagcacuca cccuacuaug     1620

aggccaugaa gaagaaagac acagagguuc ucuucugcuu ugagcaguuu gaugagcuca     1680

cccugcugca ccuucgugag uuugacaaga agaagcugau cucuguggag acggacauag     1740

ucguggauca cuacaaggag gagaaguuug aggacagguc cccagccgcc gagugccuau     1800

cagagaagga gacggaggag cucauggccu ggaugagaaa ugugcugggg ucgcguguca     1860

ccaacgugaa ggugacccuc cgacuggaca cccacccugc cauggucacc gugcuggaga     1920

ugggggcugc ccgccacuuc cugcgcaugc agcagcuggc caagacccag gaggagcgcg     1980

cacagcuccu gcagcccacg cuggagauca accccaggca cgcgcucauc aagaagcuga     2040

aucagcugcg cgcaagcgag ccuggccugg cucagcugcu gguggaucag auauacgaga     2100

acgccaugau ugcugcugga cuuguugacg acccuagggc cauggugggc cgcuugaaug     2160

agcugcuugu caaggcccug gagcgacacu gaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  6199
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (wt)

<400>  6199
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaauca gcagucuucc aacccaauua uuuaagugcu      120

gcuuuuguga uuucuugaag gugaagaugc acaccauguc cuccucgcau cucuucuacc      180

uggcgcugug ccugcucacc uucaccagcu cugccacggc uggaccggag acgcucugcg      240

gggcugagcu gguggaugcu cugcaguucg uguguggaga caggggcuuu uauuucaaca      300

agcccacagg guauggcucc agcagucgga gggcgccuca gacaggcauc guggaugagu      360

gcugcuuccg gagcugugau cuaaggaggc uggagaugua uugcgcaccc cucaagccug      420

ccaagucagc ucgcucuguc cgugcccagc gccacaccga caugcccaag acccagaagg      480

aaguacauuu gaagaacgca aguagaggga gugcaggaaa caagaacuac aggauguagg      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  6200
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (wt)

<400>  6200
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccacaagcgc cuucggucca guugccuucu      120

cccuggggcu gcuccuggug uugccugcug ccuucccugc cccaguaccc ccaggagaag      180

auuccaaaga uguagccgcc ccacacagac agccacucac cucuucagaa cgaauugaca      240

aacaaauucg guacauccuc gacggcaucu cagcccugag aaaggagaca uguaacaaga      300

guaacaugug ugaaagcagc aaagaggcac uggcagaaaa caaccugaac cuuccaaaga      360

uggcugaaaa agauggaugc uuccaaucug gauucaauga ggagacuugc cuggugaaaa      420

ucaucacugg ucuuuuggag uuugagguau accuagagua ccuccagaac agauuugaga      480

guagugagga acaagccaga gcugugcaga ugaguacaaa aguccugauc caguuccugc      540

agaaaaaggc aaagaaucua gaugcaauaa ccaccccuga cccaaccaca aaugccagcc      600

ugcugacgaa gcugcaggca cagaaccagu ggcugcagga caugacaacu caucucauuc      660

ugcgcagcuu uaaggaguuc cugcagucca gccugagggc ucugcggcaa auguagggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  6201
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (wt)

<400>  6201
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccuugcuuu ggcugagagg auuucuguug gcaaguugcu      120

ggauuauagu gaggaguucc cccaccccag gauccgaggg gcacagcgcg gcccccgacu      180

guccguccug ugcgcuggcc gcccucccaa aggauguacc caacucucag ccagagaugg      240

uggaggccgu caagaagcac auuuuaaaca ugcugcacuu gaagaagaga cccgauguca      300

cccagccggu acccaaggcg gcgcuucuga acgcgaucag aaagcugcau gugggcaaag      360

ucggggagaa cggguaugug gagauagagg augacauugg aaggagggca gaaaugaaug      420

aacuuaugga gcagaccucg gagaucauca cguuugccga gucaggaaca gccaggaaga      480

cgcugcacuu cgagauuucc aaggaaggca gugaccuguc agugguggag cgugcagaag      540

ucuggcuguu ccuaaaaguc cccaaggcca acaggaccag gaccaaaguc accauccgcc      600

ucuuccagca gcagaagcac ccgcagggca gcuuggacac aggggaagag gccgaggaag      660

ugggcuuaaa gggggagagg agugaacugu ugcucucuga aaaaguagua gacgcucgga      720

aaagcaccug gcaugucuuc ccugucucca gcagcaucca gcgguugcug gaccagggca      780

agagcucccu ggacguucgg auugccugug agcagugcca ggagaguggc gccagcuugg      840

uucuccuggg caagaagaag aagaaagaag aggaggggga agggaaaaag aagggcggag      900

gugaaggugg ggcaggagca gaugaggaaa aggagcaguc gcacagaccu uuccucaugc      960

ugcaggcccg gcagucugaa gaccacccuc aucgccggcg ucggcggggc uuggagugug     1020

auggcaaggu caacaucugc uguaagaaac aguucuuugu caguuucaag gacaucggcu     1080

ggaaugacug gaucauugcu cccucuggcu aucaugccaa cuacugcgag ggugagugcc     1140

cgagccauau agcaggcacg uccggguccu cacuguccuu ccacucaaca gucaucaacc     1200

acuaccgcau gcggggccau agccccuuug ccaaccucaa aucgugcugu gugcccacca     1260

agcugagacc cauguccaug uuguacuaug augaugguca aaacaucauc aaaaaggaca     1320

uucagaacau gaucguggag gagugugggu gcucauaggg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  6202
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (wt)

<400>  6202
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucucagag uccuucuguu aacagccuug accuuauguc      120

auggguucaa cuuggacacu gaaaacgcaa ugaccuucca agagaacgca aggggcuucg      180

ggcagagcgu gguccagcuu cagggaucca gggugguggu uggagccccc caggagauag      240

uggcugccaa ccaaaggggc agccucuacc agugcgacua cagcacaggc ucaugcgagc      300

ccauccgccu gcaggucccc guggaggccg ugaacauguc ccugggccug ucccuggcag      360

ccaccaccag ccccccucag cugcuggccu guggucccac cgugcaccag acuugcagug      420

agaacacgua ugugaaaggg cucugcuucc uguuuggauc caaccuacgg cagcagcccc      480

agaaguuccc agaggcccuc cgaggguguc cucaagagga uagugacauu gccuucuuga      540

uugauggcuc ugguagcauc aucccacaug acuuucggcg gaugaaggag uuugucucaa      600

cugugaugga gcaauuaaaa aaguccaaaa ccuuguucuc uuugaugcag uacucugaag      660

aguuccggau ucacuuuacc uucaaagagu uccagaacaa cccuaaccca agaucacugg      720

ugaagccaau aacgcagcug cuugggcgga cacacacggc cacgggcauc cgcaaagugg      780

uacgagagcu guuuaacauc accaacggag cccgaaagaa ugccuuuaag auccuaguug      840

ucaucacgga uggagaaaag uuuggcgauc ccuugggaua ugaggauguc aucccugagg      900

cagacagaga gggagucauu cgcuacguca uugggguggg agaugccuuc cgcagugaga      960

aaucccgcca agagcuuaau accaucgcau ccaagccgcc ucgugaucac guguuccagg     1020

ugaauaacuu ugaggcucug aagaccauuc agaaccagcu ucgggagaag aucuuugcga     1080

ucgaggguac ucagacagga aguagcagcu ccuuugagca ugagaugucu caggaaggcu     1140

ucagcgcugc caucaccucu aauggccccu ugcugagcac uguggggagc uaugacuggg     1200

cugguggagu cuuucuauau acaucaaagg agaaaagcac cuucaucaac augaccagag     1260

uggauucaga caugaaugau gcuuacuugg guuaugcugc cgccaucauc uuacggaacc     1320

gggugcaaag ccugguucug ggggcaccuc gauaucagca caucggccug guagcgaugu     1380

ucaggcagaa cacuggcaug ugggagucca acgcuaaugu caagggcacc cagaucggcg     1440

ccuacuucgg ggccucccuc ugcuccgugg acguggacag caacggcagc accgaccugg     1500

uccucaucgg ggccccccau uacuacgagc agacccgagg gggccaggug uccgugugcc     1560

ccuugcccag ggggagggcu cgguggcagu gugaugcugu ucucuacggg gagcagggcc     1620

aacccugggg ccgcuuuggg gcagcccuaa cagugcuggg ggacguaaau ggggacaagc     1680

ugacggacgu ggccauuggg gccccaggag aggaggacaa ccggggugcu guuuaccugu     1740

uucacggaac cucaggaucu ggcaucagcc ccucccauag ccagcggaua gcaggcucca     1800

agcucucucc caggcuccag uauuuugguc agucacugag ugggggccag gaccucacaa     1860

uggauggacu gguagaccug acuguaggag cccaggggca cgugcugcug cucagguccc     1920

agccaguacu gagagucaag gcaaucaugg aguucaaucc cagggaagug gcaaggaaug     1980

uauuugagug uaaugaucag guggugaaag gcaaggaagc cggagagguc agagucugcc     2040

uccaugucca gaaaagcaca cgggaucggc uaagagaagg acagauccag aguguuguga     2100

cuuaugaccu ggcucuggac uccggccgcc cacauucccg cgccgucuuc aaugagacaa     2160

agaacagcac acgcagacag acacaggucu uggggcugac ccagacuugu gagacccuga     2220

aacuacaguu gccgaauugc aucgaggacc cagugagccc cauugugcug cgccugaacu     2280

ucucucuggu gggaacgcca uugucugcuu ucgggaaccu ccggccagug cuggcggagg     2340

augcucagag acucuucaca gccuuguuuc ccuuugagaa gaauuguggc aaugacaaca     2400

ucugccagga ugaccucagc aucaccuuca guuucaugag ccuggacugc cucguggugg     2460

gugggccccg ggaguucaac gugacaguga cugugagaaa ugauggugag gacuccuaca     2520

ggacacaggu caccuucuuc uucccgcuug accuguccua ccggaaggug uccacgcucc     2580

agaaccagcg cucacagcga uccuggcgcc uggccuguga gucugccucc uccaccgaag     2640

ugucuggggc cuugaaaagc accagcugca gcauaaacca ccccaucuuc ccggaaaacu     2700

cagaggucac cuuuaauauc acguuugaug uagacucuaa ggcuucccuu ggaaacaaac     2760

ugcuccucaa ggccaaugug accagugaga acaacaugcc cagaaccaac aaaaccgagu     2820

uccaacugga gcugccggug aaauaugcug ucuacauggu ggucaccagc cauggggucu     2880

ccacuaaaua ucucaacuuc acggccucag agaauaccag ucgggucaug cagcaucaau     2940

aucaggucag caaccugggg cagaggagcc uccccaucag ccugguguuc uuggugcccg     3000

uccggcugaa ccagacuguc auaugggacc gcccccaggu caccuucucc gagaaccucu     3060

cgaguacgug ccacaccaag gagcgcuugc ccucucacuc cgacuuucug gcugagcuuc     3120

ggaaggcccc cguggugaac ugcuccaucg cugucugcca gagaauccag ugugacaucc     3180

cguucuuugg cauccaggaa gaguucaaug cuacccucaa aggcaaccuc ucguuugacu     3240

gguacaucaa gaccucgcau aaccaccucc ugaucgugag cacagcugag aucuuguuua     3300

acgauuccgu guucacccug cugccgggac agggggcguu ugugaggucc cagacggaga     3360

ccaaagugga gccguucgag guccccaacc cccugccgcu caucgugggc agcucugucg     3420

ggggacugcu gcuccuggcc cucaucaccg ccgcgcugua caagcucggc uucuucaagc     3480

ggcaauacaa ggacaugaug agugaagggg gucccccggg ggccgaaccc caguagggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  6203
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (wt)

<400>  6203
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucccuga agacgcuucc auuucugcuc uuacuccaug      120

ugcagauuuc caaggccuuu ccuguaucuu cuaaagagaa aaauacaaaa acuguucagg      180

acuaccugga aaaguucuac caauuaccaa gcaaccagua ucagucuaca aggaagaaug      240

gcacuaaugu gaucguugaa aagcugaaag aaaugcagcg auuuuuuggg uugaauguga      300

cggggaagcc aaaugaggaa acucuggaca ugaugaaaaa gccucgcugu ggagugccug      360

acaguggugg uuuuauguua accccaggaa accccaagug ggaacgcacu aacuugaccu      420

acaggauucg aaacuauacc ccacagcugu cagaggcuga gguagaaaga gcuaucaagg      480

augccuuuga acucuggagu guugcaucac cucucaucuu caccaggauc ucacagggag      540

aggcagauau caacauugcu uuuuaccaaa gagaucacgg ugacaauucu ccauuugaug      600

gacccaaugg aauccuugcu caugccuuuc agccaggcca agguauugga ggagaugcuc      660

auuuugaugc cgaagaaaca uggaccaaca ccuccgcaaa uuacaacuug uuucuuguug      720

cugcucauga auuuggccau ucuuuggggc ucgcucacuc cucugacccu ggugccuuga      780

uguaucccaa cuaugcuuuc agggaaacca gcaacuacuc acucccucaa gaugacaucg      840

auggcauuca ggccaucuau ggacuuucaa gcaacccuau ccaaccuacu ggaccaagca      900

cacccaaacc cugugacccc aguuugacau uugaugcuau caccacacuc cguggagaaa      960

uacuuuucuu uaaagacagg uacuucugga gaaggcaucc ucagcuacaa agagucgaaa     1020

ugaauuuuau uucucuauuc uggccauccc uuccaacugg uauacaggcu gcuuaugaag     1080

auuuugacag agaccucauu uuccuauuua aaggcaacca auacugggcu cugaguggcu     1140

augauauucu gcaagguuau cccaaggaua uaucaaacua uggcuucccc agcagcgucc     1200

aagcaauuga cgcagcuguu uucuacagaa guaaaacaua cuucuuugua aaugaccaau     1260

ucuggagaua ugauaaccaa agacaauuca uggagccagg uuaucccaaa agcauaucag     1320

gugccuuucc aggaauagag aguaaaguug augcaguuuu ccagcaagaa cauuucuucc     1380

augucuucag uggaccaaga uauuacgcau uugaucuuau ugcucagaga guuaccagag     1440

uugcaagagg caauaaaugg cuuaacugua gauauggcug aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  6204
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (wt)

<400>  6204
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccucuggc agccccuggu ccuggugcuc cuggugcugg      120

gcugcugcuu ugcugccccc agacagcgcc aguccacccu ugugcuguuc ccuggagacc      180

ugagaaccaa ucucaccgac aggcagcugg cagaggaaua ccuguaccgc uaugguuaca      240

cucggguggc agagaugcgu ggagagucga aaucucuggg gccugcgcug cugcuucucc      300

agaagcaacu gucccugccc gagaccggug agcuggauag cgccacgcug aaggccaugc      360

gaaccccacg gugcgggguc ccagaccugg gcagauucca aaccuuugag ggcgaccuca      420

aguggcacca ccacaacauc accuauugga uccaaaacua cucggaagac uugccgcggg      480

cggugauuga cgacgccuuu gcccgcgccu ucgcacugug gagcgcggug acgccgcuca      540

ccuucacucg cguguacagc cgggacgcag acaucgucau ccaguuuggu gucgcggagc      600

acggagacgg guaucccuuc gacgggaagg acgggcuccu ggcacacgcc uuuccuccug      660

gccccggcau ucagggagac gcccauuucg acgaugacga guuguggucc cugggcaagg      720

gcgucguggu uccaacucgg uuuggaaacg cagauggcgc ggccugccac uuccccuuca      780

ucuucgaggg ccgcuccuac ucugccugca ccaccgacgg ucgcuccgac ggcuugcccu      840

ggugcaguac cacggccaac uacgacaccg acgaccgguu uggcuucugc cccagcgaga      900

gacucuacac ccaggacggc aaugcugaug ggaaacccug ccaguuucca uucaucuucc      960

aaggccaauc cuacuccgcc ugcaccacgg acggucgcuc cgacggcuac cgcuggugcg     1020

ccaccaccgc caacuacgac cgggacaagc uguucggcuu cugcccgacc cgagcugacu     1080

cgacggugau ggggggcaac ucggcggggg agcugugcgu cuuccccuuc acuuuccugg     1140

guaaggagua cucgaccugu accagcgagg gccgcggaga ugggcgccuc uggugcgcua     1200

ccaccucgaa cuuugacagc gacaagaagu ggggcuucug cccggaccaa ggauacaguu     1260

uguuccucgu ggcggcgcau gaguucggcc acgcgcuggg cuuagaucau uccucagugc     1320

cggaggcgcu cauguacccu auguaccgcu ucacugaggg gccccccuug cauaaggacg     1380

acgugaaugg cauccggcac cucuaugguc cucgcccuga accugagcca cggccuccaa     1440

ccaccaccac accgcagccc acggcucccc cgacggucug ccccaccgga ccccccacug     1500

uccaccccuc agagcgcccc acagcuggcc ccacaggucc ccccucagcu ggccccacag     1560

guccccccac ugcuggcccu ucuacggcca cuacugugcc uuugaguccg guggacgaug     1620

ccugcaacgu gaacaucuuc gacgccaucg cggagauugg gaaccagcug uauuuguuca     1680

aggaugggaa guacuggcga uucucugagg gcagggggag ccggccgcag ggccccuucc     1740

uuaucgccga caaguggccc gcgcugcccc gcaagcugga cucggucuuu gaggagcggc     1800

ucuccaagaa gcuguucuuc uucucugggc gccaggugug gguguacaca ggcgcgucgg     1860

ugcugggccc gaggcgucug gacaagcugg gccugggagc cgacguggcc caggugaccg     1920

gggcccuccg gaguggcagg gggaagaugc ugcuguucag cgggcggcgc cucuggaggu     1980

ucgacgugaa ggcgcagaug guggaucccc ggagcgccag cgagguggac cggauguucc     2040

ccggggugcc uuuggacacg cacgacgucu uccaguaccg agagaaagcc uauuucugcc     2100

aggaccgcuu cuacuggcgc gugaguuccc ggagugaguu gaaccaggug gaccaagugg     2160

gcuacgugac cuaugacauc cugcagugcc cugaggacua gggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  6205
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (wt)

<400>  6205
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacuccaa acaccacaga ggacuaugac acgaccacag      120

aguuugacua uggggaugca acuccgugcc agaaggugaa cgagagggcc uuuggggccc      180

aacugcugcc cccucuguac uccuugguau uugucauugg ccugguugga aacauccugg      240

ugguccuggu ccuugugcaa uacaagaggc uaaaaaacau gaccagcauc uaccuccuga      300

accuggccau uucugaccug cuguuccugu ucacgcuucc cuucuggauc gacuacaagu      360

ugaaggauga cuggguuuuu ggugaugcca uguguaagau ccucucuggg uuuuauuaca      420

caggcuugua cagcgagauc uuuuucauca uccugcugac gauugacagg uaccuggcca      480

ucguccacgc cguguuugcc uugcgggcac ggaccgucac uuuugguguc aucaccagca      540

ucaucauuug ggcccuggcc aucuuggcuu ccaugccagg cuuauacuuu uccaagaccc      600

aaugggaguu cacucaccac accuguagcc uucacuuucc ucacgaaagc cuacgagagu      660

ggaagcuguu ucaggcucug aaacugaacc ucuuugggcu gguauugccu uuguugguca      720

ugaucaucug cuacacaggg auuauaaaga uucugcuaag acgaccaaau gagaagaaau      780

ccaaagcugu ccguuugauu uuugucauca ugaucaucuu uuuucucuuu uggacccccu      840

acaauuugac uauacuuauu ucuguuuucc aagacuuccu guucacccau gagugugagc      900

agagcagaca uuuggaccug gcugugcaag ugacggaggu gaucgccuac acgcacugcu      960

gugucaaccc agugaucuac gccuucguug gugagagguu ccggaaguac cugcggcagu     1020

uguuccacag gcguguggcu gugcaccugg uuaaauggcu ccccuuccuc uccguggaca     1080

ggcuggagag ggucagcucc acaucucccu ccacagggga gcaugaacuc ucugcugggu     1140

ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  6206
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (wt)

<400>  6206
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaucgcugcu gggcgcuguu ccugucucuc ugcugcuacc      120

ugcgucuggu cagcgccgag ggggacccca uucccgagga gcuuuaugag augcugagug      180

accacucgau ccgcuccuuu gaugaucucc aacgccugcu gcacggagac cccggagagg      240

aagauggggc cgaguuggac cugaacauga cccgcuccca cucuggaggc gagcuggaga      300

gcuuggcucg uggaagaagg agccuggguu cccugaccau ugcugagccg gccaugaucg      360

ccgagugcaa gacgcgcacc gagguguucg agaucucccg gcgccucaua gaccgcacca      420

acgccaacuu ccuggugugg ccgcccugug uggaggugca gcgcugcucc ggcugcugca      480

acaaccgcaa cgugcagugc cgccccaccc aggugcagcu gcgaccuguc caggugagaa      540

agaucgagau ugugcggaag aagccaaucu uuaagaaggc cacggugacg cuggaagacc      600

accuggcaug caagugugag acaguggcag cugcacggcc ugugacccga agcccggggg      660

guucccagga gcagcgagcc aaaacgcccc aaacucgggu gaccauucgg acggugcgag      720

uccgccggcc ccccaagggc aagcaccgga aauucaagca cacgcaugac aagacggcac      780

ugaaggagac ccuuggagcc uagggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  6207
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (wt)

<400>  6207
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccggcuca ucuuugucua cacucuaauc ugcgcaaacu      120

uuugcagcug ucgggacacu ucugcaaccc cgcagagcgc auccaucaaa gcauugcgca      180

acgccaaccu caggcgagau gacuuguacc gaagagauga gaccauccag gugaaaggaa      240

acggcuacgu gcagaguccu agauucccga acagcuaccc caggaaccug cuccugacau      300

ggcggcuuca cucucaggag aauacacgga uacagcuagu guuugacaau caguuuggau      360

uagaggaagc agaaaaugau aucuguaggu augauuuugu ggaaguugaa gauauauccg      420

aaaccaguac cauuauuaga ggacgauggu guggacacaa ggaaguuccu ccaaggauaa      480

aaucaagaac gaaccaaauu aaaaucacau ucaaguccga ugacuacuuu guggcuaaac      540

cuggauucaa gauuuauuau ucuuugcugg aagauuucca acccgcagca gcuucagaga      600

ccaacuggga aucugucaca agcucuauuu cagggguauc cuauaacucu ccaucaguaa      660

cggaucccac ucugauugcg gaugcucugg acaaaaaaau ugcagaauuu gauacagugg      720

aagaucugcu caaguacuuc aauccagagu cauggcaaga agaucuugag aauauguauc      780

uggacacccc ucgguaucga ggcaggucau accaugaccg gaagucaaaa guugaccugg      840

auaggcucaa ugaugaugcc aagcguuaca guugcacucc caggaauuac ucggucaaua      900

uaagagaaga acugaaguug gccaaugugg ucuucuuucc acguugccuc cucgugcagc      960

gcuguggagg aaauuguggc uguggaacug ucaacuggag guccugcaca ugcaauucag     1020

ggaaaaccgu gaaaaaguau caugagguau uacaguuuga gccuggccac aucaagagga     1080

gggguagagc uaagaccaug gcucuaguug acauccaguu ggaucaccau gaacgaugug     1140

auuguaucug cagcucaaga ccaccucgau aaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  6208
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (wt)

<400>  6208
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccaca gcaaguuucc cgccgccggg augagccgcc      120

cccuggacac cagccugcgc cucaagaccu ucagcuccaa gagcgaguac cagcuggugg      180

ugaacgcagu gcgcaagcug caggagagcg gcuucuacug gagcgcagug accggcggcg      240

aggcgaaccu gcugcucagu gccgagcccg ccggcaccuu ucugauccgc gacagcucgg      300

accagcgcca cuucuucacg cucagcguca agacccaguc ugggaccaag aaccugcgca      360

uccaguguga ggggggcagc uucucucugc agagcgaucc ccggagcacg cagcccgugc      420

cccgcuucga cugcgugcuc aagcuggugc accacuacau gccgcccccu ggagcccccu      480

ccuuccccuc gccaccuacu gaacccuccu ccgaggugcc cgagcagccg ucugcccagc      540

cacucccugg gagucccccc agaagggccu auuacaucua cuccgggggc gagaagaucc      600

cccugguguu gagccggccc cucuccucca acguggccac ucuucagcau cucugucgga      660

agaccgucaa cggccaccug gacuccuaug agaaagucac ccagcugccg gggcccauuc      720

gggaguuccu ggaccaguac gaugccccgc uuuaaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  6209
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (wt)

<400>  6209
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccgcccuccg ggcugcggcu gcugccgcug cugcuaccgc      120

ugcuguggcu acuggugcug acgccuggcc ggccggccgc gggacuaucc accuguaaga      180

cuaucgacau ggagcuggug aagcggaagc gcaucgaggc cauccgcggc cagauccugu      240

ccaagcugcg gcucgccagc cccccgagcc agggggaggu gccgcccggc ccgcugcccg      300

aggccgugcu cgcccuguac aacagcaccc gcgaccgggu ggccggggag agugcagaac      360

cggagcccga gccugaggcc gacuacuacg ccaaggaggu cacccgcgug cuaauggugg      420

aaacccacaa cgaaaucuau gacaaguuca agcagaguac acacagcaua uauauguucu      480

ucaacacauc agagcuccga gaagcgguac cugaacccgu guugcucucc cgggcagagc      540

ugcgucugcu gaggcucaag uuaaaagugg agcagcacgu ggagcuguac cagaaauaca      600

gcaacaauuc cuggcgauac cucagcaacc ggcugcuggc acccagcgac ucgccagagu      660

gguuaucuuu ugaugucacc ggaguugugc ggcagugguu gagccgugga ggggaaauug      720

agggcuuucg ccuuagcgcc cacugcuccu gugacagcag ggauaacaca cugcaagugg      780

acaucaacgg guucacuacc ggccgccgag gugaccuggc caccauucau ggcaugaacc      840

ggccuuuccu gcuucucaug gccaccccgc uggagagggc ccagcaucug caaagcuccc      900

ggcaccgccg agcccuggac accaacuauu gcuucagcuc cacggagaag aacugcugcg      960

ugcggcagcu guacauugac uuccgcaagg accucggcug gaaguggauc cacgagccca     1020

agggcuacca ugccaacuuc ugccucgggc ccugccccua cauuuggagc cuggacacgc     1080

aguacagcaa gguccuggcc cuguacaacc agcauaaccc gggcgccucg gcggcgccgu     1140

gcugcgugcc gcaggcgcug gagccgcugc ccaucgugua cuacgugggc cgcaagccca     1200

agguggagca gcuguccaac augaucgugc gcuccugcaa gugcagcuga ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  6210
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (wt)

<400>  6210
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugug ugcugagcgc uuuucugauc cugcaucugg      120

ucacggucgc gcucagccug ucuaccugca gcacacucga uauggaccag uucaugcgca      180

agaggaucga ggcgauccgc gggcagaucc ugagcaagcu gaagcucacc agucccccag      240

aagacuaucc ugagcccgag gaaguccccc cggaggugau uuccaucuac aacagcacca      300

gggacuugcu ccaggagaag gcgagccgga gggcggccgc cugcgagcgc gagaggagcg      360

acgaagagua cuacgccaag gagguuuaca aaauagacau gccgcccuuc uuccccuccg      420

aaaaugccau cccgcccacu uucuacagac ccuacuucag aauuguucga uuugacgucu      480

cagcaaugga gaagaaugcu uccaauuugg ugaaagcaga guucagaguc uuucguuugc      540

agaacccaaa agccagagug ccugaacaac ggauugagcu auaucagauu cucaagucca      600

aagauuuaac aucuccaacc cagcgcuaca ucgacagcaa aguugugaaa acaagagcag      660

aaggcgaaug gcucuccuuc gauguaacug augcuguuca ugaauggcuu caccauaaag      720

acaggaaccu gggauuuaaa auuagcuuac acugucccug cugcacuuuu guaccaucua      780

auaauuacau caucccaaau aaaagugaag aacuagaagc aagauuugca gguauugaug      840

gcaccuccac auauaccagu ggugaucaga aaacuauaaa guccacuagg aaaaaaaaca      900

gugggaagac cccacaucuc cugcuaaugu uauugcccuc cuacagacuu gagucacaac      960

agaccaaccg gcggaagaag cgugcuuugg augcggccua uugcuuuaga aaugugcagg     1020

auaauugcug ccuacgucca cuuuacauug auuucaagag ggaucuaggg uggaaaugga     1080

uacacgaacc caaaggguac aaugccaacu ucugugcugg agcaugcccg uauuuaugga     1140

guucagacac ucagcacagc aggguccuga gcuuauauaa uaccauaaau ccagaagcau     1200

cugcuucucc uugcugcgug ucccaagauu uagaaccucu aaccauucuc uacuacauug     1260

gcaaaacacc caagauugaa cagcuuucua auaugauugu aaagucuugc aaaugcagcu     1320

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  6211
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (wt)

<400>  6211
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacu ugcaaagggc ucuggugguc cuggcccugc      120

ugaacuuugc cacggucagc cucucucugu ccacuugcac caccuuggac uucggccaca      180

ucaagaagaa gaggguggaa gccauuaggg gacagaucuu gagcaagcuc aggcucacca      240

gccccccuga gccaacggug augacccacg uccccuauca gguccuggcc cuuuacaaca      300

gcacccggga gcugcuggag gagaugcaug gggagaggga ggaaggcugc acccaggaaa      360

acaccgaguc ggaauacuau gccaaagaaa uccauaaauu cgacaugauc caggggcugg      420

cggagcacaa cgaacuggcu gucugcccua aaggaauuac cuccaagguu uuccgcuuca      480

auguguccuc aguggagaaa aauagaacca accuauuccg agcagaguuc cgggucuugc      540

gggugcccaa ccccagcucu aagcggaaug agcagaggau cgagcuguuc cagauccuuc      600

ggccagauga gcacauugcc aaacagcgcu auaucggugg caagaaucug cccacacggg      660

gcacugccga guggcugucc uuugauguca cugacacugu gcgugagugg cuguugagaa      720

gagaguccaa cuuaggucua gaaaucagca uucacugucc augucacacc uuucagccca      780

auggagauau ccuggaaaac auucacgagg ugauggaaau caaauucaaa ggcguggaca      840

augaggauga ccauggccgu ggagaucugg ggcgccucaa gaagcagaag gaucaccaca      900

acccucaucu aauccucaug augauucccc cacaccggcu cgacaacccg ggccaggggg      960

gucagaggaa gaagcgggcu uuggacacca auuacugcuu ccgcaacuug gaggagaacu     1020

gcugugugcg cccccucuac auugacuucc gacaggaucu gggcuggaag uggguccaug     1080

aaccuaaggg cuacuaugcc aacuucugcu caggcccuug cccauaccuc cgcagugcag     1140

acacaaccca cagcacggug cugggacugu acaacacucu gaacccugaa gcaucugccu     1200

cgccuugcug cgugccccag gaccuggagc cccugaccau ccuguacuau guugggagga     1260

cccccaaagu ggagcagcuc uccaacaugg uggugaaguc uuguaaaugu agcugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6212
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (wt)

<400>  6212
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgcccgucg ccgucugggc cgcgcuggcc gucggacugg      120

agcucugggc ugcggcgcac gccuugcccg cccagguggc auuuacaccc uacgccccgg      180

agcccgggag cacaugccgg cucagagaau acuaugacca gacagcucag augugcugca      240

gcaaaugcuc gccgggccaa caugcaaaag ucuucuguac caagaccucg gacaccgugu      300

gugacuccug ugaggacagc acauacaccc agcucuggaa cuggguuccc gagugcuuga      360

gcuguggcuc ccgcuguagc ucugaccagg uggaaacuca agccugcacu cgggaacaga      420

accgcaucug caccuguagg cccggcuggu acugcgcgcu gagcaagcag gaggggugcc      480

ggcugugcgc gccgcugcgc aagugccgcc cgggcuucgg cguggccaga ccaggaacug      540

aaacaucaga cguggugugc aagcccugug ccccggggac guucuccaac acgacuucau      600

ccacggauau uugcaggccc caccagaucu guaacguggu ggccaucccu gggaaugcaa      660

gcauggaugc agucugcacg uccacguccc ccacccggag uauggcccca ggggcaguac      720

acuuacccca gccagugucc acacgauccc aacacacgca gccaacucca gaacccagca      780

cugcuccaag caccuccuuc cugcucccaa ugggccccag ccccccagcu gaagggagca      840

cuggcgacuu cgcucugcca guuggacuga uugugggugu gacagccuug ggucuacuaa      900

uaauaggagu ggugaacugu gucaucauga cccaggugaa aaagaagccc uugugccugc      960

agagagaagc caaggugccu cacuugccug ccgauaaggc ccgggguaca cagggccccg     1020

agcagcagca ccuccugauc acagcgccga gcuccagcag cagcucccug gagagcucgg     1080

ccagugcguu ggacagaagg gcgcccacuc ggaaccagcc acaggcacca ggcguggagg     1140

ccaguggggc cggggaggcc cgggccagca ccgggagcuc agauucuucc ccugguggcc     1200

augggaccca ggucaauguc accuguaucg ugaacgucug uagcagcucu gaccacagcu     1260

cacagugcuc cucccaagcc agcuccacaa ugggagacac agauuccagc cccucggagu     1320

ccccgaagga cgagcagguc cccuucucca aggaggaaug ugccuuucgg ucacagcugg     1380

agacgccaga gacccugcug gggagcaccg aagagaagcc ccugccccuu ggagugccug     1440

augcugggau gaagcccagu uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  6213
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (wt)

<400>  6213
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagagu ggguaguggu gaauguuuuc augauguugu      120

acguccagcu ggugcagggc uccaguaaug aacauggacc agugaagcga ucaucucagu      180

ccacauugga acgaucugaa cagcagauca gggcugcuuc uaguuuggag gaacuacuuc      240

gaauuacuca cucugaggac uggaagcugu ggagaugcag gcugaggcuc aaaaguuuua      300

ccaguaugga cucucgcuca gcaucccauc gguccacuag guuugcggca acuuucuaug      360

acauugaaac acuaaaaguu auagaugaag aauggcaaag aacucagugc agcccuagag      420

aaacgugcgu ggagguggcc agugagcugg ggaagaguac caacacauuc uucaagcccc      480

cuugugugaa cguguuccga ugugguggcu guugcaauga agagagccuu aucuguauga      540

acaccagcac cucguacauu uccaaacagc ucuuugagau aucagugccu uugacaucag      600

uaccugaauu agugccuguu aaaguugcca aucauacagg uuguaagugc uugccaacag      660

ccccccgcca uccauacuca auuaucagaa gauccaucca gaucccugaa gaagaucgcu      720

guucccauuc caagaaacuc uguccuauug acaugcuaug ggauagcaac aaauguaaau      780

guguuuugca ggaggaaaau ccacuugcug gaacagaaga ccacucucau cuccaggaac      840

cagcucucug ugggccacac augauguuug acgaagaucg uugcgagugu gucuguaaaa      900

caccaugucc caaagaucua auccagcacc ccaaaaacug caguugcuuu gagugcaaag      960

aaagucugga gaccugcugc cagaagcaca agcuauuuca cccagacacc uguagcugug     1020

aggacagaug ccccuuucau accagaccau gugcaagugg caaaacagca ugugcaaagc     1080

auugccgcuu uccaaaggag aaaagggcug cccaggggcc ccacagccga aagaauccuu     1140

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  6214
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (wt)

<400>  6214
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucggacg agaccggguu cgagcacuca ggacuguggg      120

uuucugugcu ggcuggucuu cugcugggag ccugccaggc acaccccauc ccugacucca      180

guccucuccu gcaauucggg ggccaagucc ggcagcggua ccucuacaca gaugaugccc      240

agcagacaga agcccaccug gagaucaggg aggaugggac gguggggggc gcugcugacc      300

agagccccga aagucuccug cagcugaaag ccuugaagcc gggaguuauu caaaucuugg      360

gagucaagac auccagguuc cugugccagc ggccagaugg ggcccuguau ggaucgcucc      420

acuuugaccc ugaggccugc agcuuccggg agcugcuucu ugaggacgga uacaauguuu      480

accaguccga agcccacggc cucccgcugc accugccagg gaacaagucc ccacaccggg      540

acccugcacc ccgaggacca gcucgcuucc ugccacuacc aggccugccc cccgcacucc      600

cggagccacc cggaauccug gccccccagc cccccgaugu gggcuccucg gacccucuga      660

gcaugguggg accuucccag ggccgaagcc ccagcuacgc uuccugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  6215
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (wt) R5987

<400>  6215
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucggacg agaccggguu cgagcacuca ggacuguggg      120

uuucugugcu ggcuggucuu cugcugggag ccugccaggc acaccccauc ccugacucca      180

guccucuccu gcaauucggg ggccaagucc ggcagcggua ccucuacaca gaugaugccc      240

agcagacaga agcccaccug gagaucaggg aggaugggac gguggggggc gcugcugacc      300

agagccccga aagucuccug cagcugaaag ccuugaagcc gggaguuauu caaaucuugg      360

gagucaagac auccagguuc cugugccagc ggccagaugg ggcccuguau ggaucgcucc      420

acuuugaccc ugaggccugc agcuuccggg agcugcuucu ugaggacgga uacaauguuu      480

accaguccga agcccacggc cucccgcugc accucccagg gaacaagucc ccacaccggg      540

acccugcacc ccgaggacca gcucgcuucc ugccacuacc aggccugccc cccgcacucc      600

cggagccacc cggaauccug gccccccagc cccccgaugu gggcuccucg gacccucuga      660

gcaugguggg accuucccag ggccgaagcc ccagcuacgc uuccugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  6216
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (wt)

<400>  6216
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc cuccacugcu gcugcugcug uucuggggug      120

uggugucuca cagcuuccca gcgacucuag aaacacaaga gcaagaugug gacuuagucc      180

agaaauaccu ggaaaaauac uacaaccuga agaaugaugg gaggcaaguu gaaaagcgga      240

gaaauagugg cccagugguu gaaaaauuga agcaaaugca ggaauucuuu gggcugaaag      300

ugacugggaa accagaugcu gaaacccuga aggugaugaa gcagcccaga uguggagugc      360

cugauguggc ucaguuuguc cucacugagg ggaacccucg cugggagcaa acacaucuga      420

ccuacaggau ugaaaauuac acgccagauu ugccaagagc agauguggac caugccauug      480

agaaagccuu ccaacucugg aguaauguca caccucugac auucaccaag gucucugagg      540

gucaagcaga caucaugaua ucuuuuguca ggggagauca ucgggacaac ucuccuuuug      600

auggaccugg aggaaaucuu gcucaugcuu uucaaccagg cccagguauu ggaggggaug      660

cucauuuuga ugaagaugaa agguggacca acaauuucag agaguacaac uuacaucgug      720

uugcagcuca ugaacucggc cauucucuug gacucuccca uucuacugau aucggggcuu      780

ugauguaccc uagcuacacc uucaguggug auguucagcu agcucaggau gacauugaug      840

gcauccaagc cauauaugga cguucccaaa auccugucca gcccaucggc ccacaaaccc      900

caaaagcgug ugacaguaag cuaaccuuug augcuauaac uacgauucgg ggagaaguga      960

uguucuuuaa agacagauuc uacaugcgca caaaucccuu cuacccggaa guugagcuca     1020

auuucauuuc uguuuucugg ccacaacugc caaaugggcu ugaagcugcu uacgaauuug     1080

ccgacagaga ugaaguccgg uuuuucaaag ggaauaagua cugggcuguu cagggacaga     1140

augugcuaca cggauacccc aaggacaucu acagcuccuu uggcuucccu agaacuguga     1200

agcauaucga ugcugcucuu ucugaggaaa acacuggaaa aaccuacuuc uuuguugcua     1260

acaaauacug gagguaugau gaauauaaac gaucuaugga uccagguuau cccaaaauga     1320

uagcacauga cuuuccugga auuggccaca aaguugaugc aguuuucaug aaagauggau     1380

uuuucuauuu cuuucaugga acaagacaau acaaauuuga uccuaaaacg aagagaauuu     1440

ugacucucca gaaagcuaau agcugguuca acugcaggaa aaauugagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  6217
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (wt)

<400>  6217
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc cuccacugcu gcugcugcug uucuggggug      120

uggugucuca cagcuuccca gcgacucuag aaacacaaga gcaagaugug gacuuagucc      180

agaaauaccu ggaaaaauac uacaaccuga agaaugaugg gaggcaaguu gaaaagcgga      240

gaaauagugg cccagugguu gaaaaauuga agcaaaugca ggaguucuuu gggcugaaag      300

ugacugggaa accagaugcu gaaacccuga aggugaugaa gcagcccaga uguggagugc      360

cugauguggc ucaguuuguc cucacugagg ggaacccucg cugggagcaa acacaucuga      420

ccuacaggau ugaaaauuac acgccagauu ugccaagagc agauguggac caugccauug      480

agaaagccuu ccaacucugg aguaauguca caccucugac auucaccaag gucucugagg      540

gucaagcaga caucaugaua ucuuuuguca ggggagauca ucgggacaac ucuccuuuug      600

auggaccugg aggaaaucuu gcucaugcuu uucaaccagg cccagguauu ggaggggaug      660

cucauuuuga ugaagaugaa agguggacca acaauuucag agaguacaac uuacaucgug      720

uugcagcuca ugaacucggc cauucucuug gacucuccca uucuacugau aucggggcuu      780

ugauguaccc uagcuacacc uucaguggug auguucagcu agcucaggau gacauugaug      840

gcauccaagc cauauaugga cguucccaaa auccugucca gcccaucggc ccacaaaccc      900

caaaagcgug ugacaguaag cuaaccuuug augcuauaac uacgauucgg ggagaaguga      960

uguucuuuaa agacagauuc uacaugcgca caaaucccuu cuacccggaa guugagcuca     1020

auuucauuuc uguuuucugg ccacaacugc caaaugggcu ugaagcugcu uacgaauuug     1080

ccgacagaga ugaaguccgg uuuuucaaag ggaauaagua cugggcuguu cagggacaga     1140

augugcuaca cggauacccc aaggacaucu acagcuccuu uggcuucccu agaacuguga     1200

agcauaucga ugcugcucuu ucugaggaaa acacuggaaa aaccuacuuc uuuguugcua     1260

acaaauacug gagguaugau gaauauaaac gaucuaugga uccagguuau cccaaaauga     1320

uagcacauga cuuuccugga auuggccaca aaguugaugc aguuuucaug aaagauggau     1380

uuuucuauuu cuuucaugga acaagacaau acaaauuuga uccuaaaacg aagagaauuu     1440

ugacucucca gaaagcuaau agcugguuca acugcaggaa aaauugagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  6218
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (wt)

<400>  6218
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc cuccacugcu gcugcugcug uucuggggug      120

uggugucuca cagcuuuguc cucacugagg ggaacccucg cugggagcaa acacaucuga      180

ccuacaggau ugaaaauuac acgccagauu ugccaagagc agauguggac caugccauug      240

agaaagccuu ccaacucugg aguaauguca caccucugac auucaccaag gucucugagg      300

gucaagcaga caucaugaua ucuuuuguca ggggagauca ucgggacaac ucuccuuuug      360

auggaccugg aggaaaucuu gcucaugcuu uucaaccagg cccagguauu ggaggggaug      420

cucauuuuga ugaagaugaa agguggacca acaauuucag agaguacaac uuacaucgug      480

uugcagcuca ugaacucggc cauucucuug gacucuccca uucuacugau aucggggcuu      540

ugauguaccc uagcuacacc uucaguggug auguucagcu agcucaggau gacauugaug      600

gcauccaagc cauauaugga cguucccaaa auccugucca gcccaucggc ccacaaaccc      660

caaaagcgug ugacaguaag cuaaccuuug augcuauaac uacgauucgg ggagaaguga      720

uguucuuuaa agacagauuc uacaugcgca caaaucccuu cuacccggaa guugagcuca      780

auuucauuuc uguuuucugg ccacaacugc caaaugggcu ugaagcugcu uacgaauuug      840

ccgacagaga ugaaguccgg uuuuucaaag ggaauaagua cugggcuguu cagggacaga      900

augugcuaca cggauacccc aaggacaucu acagcuccuu uggcuucccu agaacuguga      960

agcauaucga ugcugcucuu ucugaggaaa acacuggaaa aaccuacuuc uuuguugcua     1020

acaaauacug gagguaugau gaauauaaac gaucuaugga uccagguuau cccaaaauga     1080

uagcacauga cuuuccugga auuggccaca aaguugaugc aguuuucaug aaagauggau     1140

uuuucuauuu cuuucaugga acaagacaau acaaauuuga uccuaaaacg aagagaauuu     1200

ugacucucca gaaagcuaau agcugguuca acugcaggaa aaauugagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  6219
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (wt)

<400>  6219
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaaaaaua uuuuaaagau ucuuauggau aguuauucua      120

aagaaucuaa aauucaaacu guacguaggg uuacgagugu aucacuuuua gcgguauauc      180

uuacuaugaa uacuucaagu uuaguuuuag caaaaccaau agaaaauacu aaugauacua      240

guauaaaaaa uguggagaaa uuaagaaaug cuccaaauga agagaauagu aaaaagguag      300

aagauaguaa aaaugauaag guagaacaug ugaaaaauau agaagaggca aagguugagc      360

aaguugcacc cgaaguaaaa ucuaaaucaa cuuuaagaag ugcuucuaua gcgaauacua      420

auucugagaa auaugauuuu gaguauuuaa augguuugag cuauacugaa cuuacaaauu      480

uaauuaaaaa uauaaagugg aaucaaauua augguuuauu uaauuauagu acagguucuc      540

aaaaguucuu uggagauaaa aaucguguac aagcuauaau uaaugcuuua caagaaagug      600

gaagaacuua cacugcaaau gauaugaagg guauagaaac uuucacugag guuuuaagag      660

cugguuuuua uuuaggguac uauaaugaug guuuaucuua uuuaaaugau agaaacuucc      720

aagauaaaug uauaccugca augauugcaa uucaaaaaaa uccuaacuuu aagcuaggaa      780

cugcaguuca agaugaaguu auaacuucuu uaggaaaacu aauaggaaau gcuucugcua      840

augcugaagu aguuaauaau uguguaccag uucuaaaaca auuuagagaa aacuuaaauc      900

aauaugcucc ugauuacguu aaaggaacag cuguaaauga auuaauuaaa gguauugaau      960

ucgauuuuuc uggugcugca uaugaaaaag auguuaagac aaugccuugg uauggaaaaa     1020

uugauccauu uauaaaugaa cuuaaggccu uaggucuaua uggaaauaua acaagugcaa     1080

cugagugggc aucugauguu ggaauauacu auuuaaguaa auucggucuu uacucaacua     1140

accgaaauga cauaguacag ucacuugaaa aggcuguaga uauguauaag uaugguaaaa     1200

uagccuuugu agcaauggag agaauaacuu gggauuauga ugggauuggu ucuaauggua     1260

aaaaggugga ucacgauaag uucuuagaug augcugaaaa acauuaucug ccaaagacau     1320

auacuuuuga uaauggaacc uuuauuauaa gagcagggga uaagguaucc gaagaaaaaa     1380

uaaaaaggcu auauugggca ucaagagaag ugaagucuca auuccauaga guaguuggca     1440

augauaaagc uuuagaggug ggaaaugccg augauguuuu aacuaugaaa auauuuaaua     1500

gcccagaaga auauaaauuu aauaccaaua uaaauggugu aagcacugau aauggugguc     1560

uauauauaga accaagaggg acuuucuaca cuuaugagag aacaccucaa caaaguauau     1620

uuagucuuga agaauuguuu agacaugaau auacucacua uuuacaagcg agauaucuug     1680

uagaugguuu augggggcaa gguccauuuu augaaaaaaa uagauuaacu ugguuugaug     1740

aagguacagc ugaauucuuu gcaggaucua cccguacauc ugguguuuua ccaagaaaau     1800

caauauuagg auauuuggcu aaggauaaag uagaucauag auacucauua aagaagacuc     1860

uuaauucagg guaugaugac agugauugga uguucuauaa uuauggauuu gcaguugcac     1920

auuaccuaua ugaaaaagau augccuacau uuauuaagau gaauaaagcu auauugaaua     1980

cagaugugaa aucuuaugau gaaauaauaa aaaaauuaag ugaugaugca aauaaaaaua     2040

cagaauauca aaaccauauu caagaguuag cagauaaaua ucaaggagca ggcauaccuc     2100

uaguaucaga ugauuacuua aaagaucaug gauauaagaa agcaucugaa guauauucug     2160

aaauuucaaa agcugcuucu cuuacaaaca cuaguguaac agcagaaaaa ucucaauauu     2220

uuaacacauu cacuuuaaga ggaacuuaua caggugaaac uucuaaaggu gaauuuaaag     2280

auugggauga aaugaguaaa aaauuagaug gaacuuugga gucccuugcu aaaaauucuu     2340

ggaguggaua caaaacuuua acagcauacu uuacgaauua uagaguuaca agcgauaaua     2400

aaguucaaua ugauguaguu uuccaugggg uuuuaacaga uaaugcggau auuaguaaca     2460

auaaggcucc aauagcaaag guaacuggac caagcacugg ugcuguagga agaaauauug     2520

aauuuagugg aaaagauagu aaagaugaag augguaaaau aguaucauau gauugggauu     2580

uuggcgaugg ugcaacuagu agaggcaaaa auucaguaca ugcuuacaaa aaagcaggaa     2640

cauauaaugu uacauuaaaa guaacugacg auaagggugc aacagcuaca gaaagcuuua     2700

cuauagaaau aaagaacgaa gauacaacaa caccuauaac uaaagaaaug gaaccuaaug     2760

augauauaaa agaggcuaau gguccaauag uugaaggugu uacuguaaaa ggugauuuaa     2820

augguucuga ugaugcugau accuucuauu uugauguaaa agaagauggu gauguuacaa     2880

uugaacuucc uuauucaggg ucaucuaauu ucacaugguu aguuuauaaa gagggagacg     2940

aucaaaacca uauugcaagu gguauagaua agaauaacuc aaaaguugga acauuuaaau     3000

cuacaaaagg aagacauuau guguuuauau auaaacacga uucugcuuca aauauauccu     3060

auucuuuaaa cauaaaagga uuagguaacg agaaauugaa ggaaaaagaa aauaaugauu     3120

cuucugauaa agcuacaguu auaccaaauu ucaauaccac uaugcaaggu ucacuuuuag     3180

gugaugauuc aagagauuau uauucuuuug agguuaagga agaaggcgaa guuaauauag     3240

aacuagauaa aaaggaugaa uuugguguaa cauggacacu acauccagag ucaaauauua     3300

augacagaau aacuuacgga caaguugaug guaauaaggu aucuaauaaa guuaaauuaa     3360

gaccaggaaa auauuaucua cuuguuuaua aauacucagg aucaggaaac uaugaguuaa     3420

ggguaaauaa auaaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  6220
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (wt)

<400>  6220
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaaaaaua uuuuaaagau ucuuauggau aguuauucua      120

aagaaucuaa aauucaaacu guacguaggg uuacgagugu aucacuuuua gcgguauauc      180

uuacuaugaa uacuucaagu uuaguuuuag caaaaccaau agaaaauacu aaugauacaa      240

guauaaaaaa uguggagaaa uuaagaaaug cuccaaauga agagaauagu aaaaagguag      300

aagauaguaa aaaugauaag guagaacaug ugaaaaauau agaagaggca aagguugagc      360

aaguugcacc cgaaguaaaa ucuaaaucaa cuuuaagaag ugcuucuaua gcgaauacua      420

auucugagaa auaugauuuu gaguauuuaa augguuugag cuauacugaa cuuacaaauu      480

uaauuaaaaa uauaaagugg aaucaaauua augguuuauu uaauuauagu acagguucuc      540

aaaaguucuu uggagauaaa aaucguguac aagcuauaau uaaugcuuua caagaaagug      600

gaagaacuua cacugcaaau gauaugaagg guauagaaac uuucacugag guuuuaagag      660

cugguuuuua uuuaggguac uauaaugaug guuuaucuua uuuaaaugau agaaacuucc      720

aagauaaaug uauaccugca augauugcaa uucaaaaaaa uccuaacuuu aagcuaggaa      780

cugcaguuca agaugaaguu auaacuucuu uaggaaaacu aauaggaaau gcuucugcua      840

augcugaagu aguuaauaau uguguaccag uucuaaaaca auuuagagaa aacuuaaauc      900

aauaugcucc ugauuacguu aaaggaacag cuguaaauga auuaauuaaa gguauugagu      960

ucgauuuuuc uggugcugca uaugaaaaag auguuaagac aaugccuugg uauggaaaaa     1020

uugauccauu uauaaaugaa cuuaaggccu uaggucuaua uggaaauaua acaagugcaa     1080

cugagugggc aucugauguu ggaauauacu auuuaaguaa auucggucuu uacucaacua     1140

accgaaauga cauaguacag ucacuugaaa aggcuguaga uauguauaag uaugguaaaa     1200

uagccuuugu agcaauggag agaauaacuu gggauuauga ugggauuggu ucuaauggua     1260

aaaaggugga ucacgauaag uucuuagaug augcugaaaa acauuaucug ccaaagacau     1320

auacuuuuga uaauggaacc uuuauuauaa gagcagggga uaagguaucc gaagaaaaaa     1380

uaaaaaggcu auauugggca ucaagagaag ugaagucuca auuccauaga guaguuggca     1440

augauaaagc auuagaggug ggaaaugccg augauguuuu aacuaugaaa auauuuaaua     1500

gcccagaaga auauaaauuu aauaccaaua uaaauggugu aagcacugau aauggugguc     1560

uauauauaga accaagaggg acuuucuaca cuuaugagag aacaccucaa caaaguauau     1620

uuagucuuga agaauuguuu agacaugaau auacucacua uuuacaagcg agauaucuug     1680

uagaugguuu augggggcaa gguccauuuu augaaaaaaa uagauuaacu ugguuugaug     1740

aagguacagc ugaguucuuu gcaggaucua cccguacauc ugguguuuua ccaagaaaau     1800

caauauuagg auauuuggcu aaggauaaag uagaucauag auacucauua aagaagacuc     1860

uuaauucagg guaugaugac agugauugga uguucuauaa uuauggauuu gcaguugcac     1920

auuaccuaua ugaaaaagau augccuacau uuauuaagau gaauaaagcu auauugaaua     1980

cagaugugaa aucuuaugau gaaauaauaa aaaaauuaag ugaugaugca aauaaaaaua     2040

cagaauauca aaaccauauu caagaguuag cagauaaaua ucaaggagca ggcauaccuc     2100

uaguaucaga ugauuacuua aaagaucaug gauauaagaa agcaucugaa guauauucug     2160

aaauuucaaa agcugcuucu cuuacaaaca caaguguaac agcagaaaaa ucucaauauu     2220

uuaacacauu cacuuuaaga ggaacuuaua caggugaaac uucuaaaggu gaauuuaaag     2280

auugggauga aaugaguaaa aaauuagaug gaacuuugga gucccuugcu aaaaauucuu     2340

ggaguggaua caaaacuuua acagcauacu uuacgaauua uagaguuaca agcgauaaua     2400

aaguucaaua ugauguaguu uuccaugggg uuuuaacaga uaaugcggau auuaguaaca     2460

auaaggcucc aauagcaaag guaacuggac caagcacugg ugcuguagga agaaauauug     2520

aauuuagugg aaaagauagu aaagaugaag augguaaaau aguaucauau gauugggauu     2580

uuggcgaugg ugcaacaagu agaggcaaaa auucaguaca ugcuuacaaa aaagcaggaa     2640

cauauaaugu uacauuaaaa guaacugacg auaagggugc aacagcuaca gagagcuuua     2700

cuauagaaau aaagaacgaa gauacaacaa caccuauaac uaaagaaaug gaaccuaaug     2760

augauauaaa agaggcuaau gguccaauag uugaaggugu uacuguaaaa ggugauuuaa     2820

augguucuga ugaugcugau accuucuauu uugauguaaa agaagauggu gauguuacaa     2880

uugaacuucc uuauucaggg ucaucuaauu ucacaugguu aguuuauaaa gagggagacg     2940

aucaaaacca uauugcaagu gguauagaua agaauaacuc aaaaguugga acauuuaaau     3000

cuacaaaagg aagacauuau guguuuauau auaaacacga uucugcuuca aauauauccu     3060

auucuuuaaa cauaaaagga uuagguaacg agaaauugaa ggaaaaagaa aauaaugauu     3120

cuucugauaa agcuacaguu auaccaaauu ucaauaccac uaugcaaggu ucacuuuuag     3180

gugaugauuc aagagauuau uauucuuuug agguuaagga agaaggcgaa guuaauauag     3240

aacuagauaa aaaggaugaa uuugguguaa cauggacacu acauccagag ucaaauauua     3300

augacagaau aacuuacgga caaguugaug guaauaaggu aucuaauaaa guuaaauuaa     3360

gaccaggaaa auauuaucua cuuguuuaua aauacucagg aucaggaaac uaugaguuaa     3420

ggguaaauaa auaaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  6221
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (wt)

<400>  6221
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc cauagcgaau acuaauucug agaaauauga uuuugaguau uuaaaugguu      180

ugagcuauac ugaacuuaca aauuuaauua aaaauauaaa guggaaucaa auuaaugguu      240

uauuuaauua uaguacaggu ucucaaaagu ucuuuggaga uaaaaaucgu guacaagcua      300

uaauuaaugc uuuacaagaa aguggaagaa cuuacacugc aaaugauaug aaggguauag      360

aaacuuucac ugagguuuua agagcugguu uuuauuuagg guacuauaau gaugguuuau      420

cuuauuuaaa ugauagaaac uuccaagaua aauguauacc ugcaaugauu gcaauucaaa      480

aaaauccuaa cuuuaagcua ggaacugcag uucaagauga aguuauaacu ucuuuaggaa      540

aacuaauagg aaaugcuucu gcuaaugcug aaguaguuaa uaauugugua ccaguucuaa      600

aacaauuuag agaaaacuua aaucaauaug cuccugauua cguuaaagga acagcuguaa      660

augaauuaau uaaagguauu gaauucgauu uuucuggugc ugcauaugaa aaagauguua      720

agacaaugcc uugguaugga aaaauugauc cauuuauaaa ugaacuuaag gccuuagguc      780

uauauggaaa uauaacaagu gcaacugagu gggcaucuga uguuggaaua uacuauuuaa      840

guaaauucgg ucuuuacuca acuaaccgaa augacauagu acagucacuu gaaaaggcug      900

uagauaugua uaaguauggu aaaauagccu uuguagcaau ggagagaaua acuugggauu      960

augaugggau ugguucuaau gguaaaaagg uggaucacga uaaguucuua gaugaugcug     1020

aaaaacauua ucugccaaag acauauacuu uugauaaugg aaccuuuauu auaagagcag     1080

gggauaaggu auccgaagaa aaaauaaaaa ggcuauauug ggcaucaaga gaagugaagu     1140

cucaauucca uagaguaguu ggcaaugaua aagcuuuaga ggugggaaau gccgaugaug     1200

uuuuaacuau gaaaauauuu aauagcccag aagaauauaa auuuaauacc aauauaaaug     1260

guguaagcac ugauaauggu ggucuauaua uagaaccaag agggacuuuc uacacuuaug     1320

agagaacacc ucaacaaagu auauuuaguc uugaagaauu guuuagacau gaauauacuc     1380

acuauuuaca agcgagauau cuuguagaug guuuaugggg gcaaggucca uuuuaugaaa     1440

aaaauagauu aacuugguuu gaugaaggua cagcugaauu cuuugcagga ucuacccgua     1500

caucuggugu uuuaccaaga aaaucaauau uaggauauuu ggcuaaggau aaaguagauc     1560

auagauacuc auuaaagaag acucuuaauu caggguauga ugacagugau uggauguucu     1620

auaauuaugg auuugcaguu gcacauuacc uauaugaaaa agauaugccu acauuuauua     1680

agaugaauaa agcuauauug aauacagaug ugaaaucuua ugaugaaaua auaaaaaaau     1740

uaagugauga ugcaaauaaa aauacagaau aucaaaacca uauucaagag uuagcagaua     1800

aauaucaagg agcaggcaua ccucuaguau cagaugauua cuuaaaagau cauggauaua     1860

agaaagcauc ugaaguauau ucugaaauuu caaaagcugc uucucuuaca aacacuagug     1920

uaacagcaga aaaaucucaa uauuuuaaca cauucacuuu aagaggaacu uauacaggug     1980

aaacuucuaa aggugaauuu aaagauuggg augaaaugag uaaaaaauua gauggaacuu     2040

uggagucccu ugcuaaaaau ucuuggagug gauacaaaac uuuaacagca uacuuuacga     2100

auuauagagu uacaagcgau aauaaaguuc aauaugaugu aguuuuccau gggguuuuaa     2160

cagauaaugc ggauauuagu aacaauaagg cuccaauagc aaagguaacu ggaccaagca     2220

cuggugcugu aggaagaaau auugaauuua guggaaaaga uaguaaagau gaagauggua     2280

aaauaguauc auaugauugg gauuuuggcg auggugcaac uaguagaggc aaaaauucag     2340

uacaugcuua caaaaaagca ggaacauaua auguuacauu aaaaguaacu gacgauaagg     2400

gugcaacagc uacagaaagc uuuacuauag aaauaaagaa cgaagauaca acaacaccua     2460

uaacuaaaga aauggaaccu aaugaugaua uaaaagaggc uaauggucca auaguugaag     2520

guguuacugu aaaaggugau uuaaaugguu cugaugaugc ugauaccuuc uauuuugaug     2580

uaaaagaaga uggugauguu acaauugaac uuccuuauuc agggucaucu aauuucacau     2640

gguuaguuua uaaagaggga gacgaucaaa accauauugc aagugguaua gauaagaaua     2700

acucaaaagu uggaacauuu aaaucuacaa aaggaagaca uuauguguuu auauauaaac     2760

acgauucugc uucaaauaua uccuauucuu uaaacauaaa aggauuaggu aacgagaaau     2820

ugaaggaaaa agaaaauaau gauucuucug auaaagcuac aguuauacca aauuucaaua     2880

ccacuaugca agguucacuu uuaggugaug auucaagaga uuauuauucu uuugagguua     2940

aggaagaagg cgaaguuaau auagaacuag auaaaaagga ugaauuuggu guaacaugga     3000

cacuacaucc agagucaaau auuaaugaca gaauaacuua cggacaaguu gaugguaaua     3060

agguaucuaa uaaaguuaaa uuaagaccag gaaaauauua ucuacuuguu uauaaauacu     3120

caggaucagg aaacuaugag uuaaggguaa auaaauaagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  6222
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (wt)

<400>  6222
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc cauagcgaau acuaauucug agaaauauga uuuugaguau uuaaaugguu      180

ugagcuauac ugaacuuaca aauuuaauua aaaauauaaa guggaaucaa auuaaugguu      240

uauuuaauua uaguacaggu ucucaaaagu ucuuuggaga uaaaaaucgu guacaagcua      300

uaauuaaugc uuuacaagaa aguggaagaa cuuacacugc aaaugauaug aaggguauag      360

aaacuuucac ugagguuuua agagcugguu uuuauuuagg guacuauaau gaugguuuau      420

cuuauuuaaa ugauagaaac uuccaagaua aauguauacc ugcaaugauu gcaauucaaa      480

aaaauccuaa cuuuaagcua ggaacugcag uucaagauga aguuauaacu ucuuuaggaa      540

aacuaauagg aaaugcuucu gcuaaugcug aaguaguuaa uaauugugua ccaguucuaa      600

aacaauuuag agaaaacuua aaucaauaug cuccugauua cguuaaagga acagcuguaa      660

augaauuaau uaaagguauu gaguucgauu uuucuggugc ugcauaugaa aaagauguua      720

agacaaugcc uugguaugga aaaauugauc cauuuauaaa ugaacuuaag gccuuagguc      780

uauauggaaa uauaacaagu gcaacugagu gggcaucuga uguuggaaua uacuauuuaa      840

guaaauucgg ucuuuacuca acuaaccgaa augacauagu acagucacuu gaaaaggcug      900

uagauaugua uaaguauggu aaaauagccu uuguagcaau ggagagaaua acuugggauu      960

augaugggau ugguucuaau gguaaaaagg uggaucacga uaaguucuua gaugaugcug     1020

aaaaacauua ucugccaaag acauauacuu uugauaaugg aaccuuuauu auaagagcag     1080

gggauaaggu auccgaagaa aaaauaaaaa ggcuauauug ggcaucaaga gaagugaagu     1140

cucaauucca uagaguaguu ggcaaugaua aagcauuaga ggugggaaau gccgaugaug     1200

uuuuaacuau gaaaauauuu aauagcccag aagaauauaa auuuaauacc aauauaaaug     1260

guguaagcac ugauaauggu ggucuauaua uagaaccaag agggacuuuc uacacuuaug     1320

agagaacacc ucaacaaagu auauuuaguc uugaagaauu guuuagacau gaauauacuc     1380

acuauuuaca agcgagauau cuuguagaug guuuaugggg gcaaggucca uuuuaugaaa     1440

aaaauagauu aacuugguuu gaugaaggua cagcugaguu cuuugcagga ucuacccgua     1500

caucuggugu uuuaccaaga aaaucaauau uaggauauuu ggcuaaggau aaaguagauc     1560

auagauacuc auuaaagaag acucuuaauu caggguauga ugacagugau uggauguucu     1620

auaauuaugg auuugcaguu gcacauuacc uauaugaaaa agauaugccu acauuuauua     1680

agaugaauaa agcuauauug aauacagaug ugaaaucuua ugaugaaaua auaaaaaaau     1740

uaagugauga ugcaaauaaa aauacagaau aucaaaacca uauucaagag uuagcagaua     1800

aauaucaagg agcaggcaua ccucuaguau cagaugauua cuuaaaagau cauggauaua     1860

agaaagcauc ugaaguauau ucugaaauuu caaaagcugc uucucuuaca aacacaagug     1920

uaacagcaga aaaaucucaa uauuuuaaca cauucacuuu aagaggaacu uauacaggug     1980

aaacuucuaa aggugaauuu aaagauuggg augaaaugag uaaaaaauua gauggaacuu     2040

uggagucccu ugcuaaaaau ucuuggagug gauacaaaac uuuaacagca uacuuuacga     2100

auuauagagu uacaagcgau aauaaaguuc aauaugaugu aguuuuccau gggguuuuaa     2160

cagauaaugc ggauauuagu aacaauaagg cuccaauagc aaagguaacu ggaccaagca     2220

cuggugcugu aggaagaaau auugaauuua guggaaaaga uaguaaagau gaagauggua     2280

aaauaguauc auaugauugg gauuuuggcg auggugcaac aaguagaggc aaaaauucag     2340

uacaugcuua caaaaaagca ggaacauaua auguuacauu aaaaguaacu gacgauaagg     2400

gugcaacagc uacagagagc uuuacuauag aaauaaagaa cgaagauaca acaacaccua     2460

uaacuaaaga aauggaaccu aaugaugaua uaaaagaggc uaauggucca auaguugaag     2520

guguuacugu aaaaggugau uuaaaugguu cugaugaugc ugauaccuuc uauuuugaug     2580

uaaaagaaga uggugauguu acaauugaac uuccuuauuc agggucaucu aauuucacau     2640

gguuaguuua uaaagaggga gacgaucaaa accauauugc aagugguaua gauaagaaua     2700

acucaaaagu uggaacauuu aaaucuacaa aaggaagaca uuauguguuu auauauaaac     2760

acgauucugc uucaaauaua uccuauucuu uaaacauaaa aggauuaggu aacgagaaau     2820

ugaaggaaaa agaaaauaau gauucuucug auaaagcuac aguuauacca aauuucaaua     2880

ccacuaugca agguucacuu uuaggugaug auucaagaga uuauuauucu uuugagguua     2940

aggaagaagg cgaaguuaau auagaacuag auaaaaagga ugaauuuggu guaacaugga     3000

cacuacaucc agagucaaau auuaaugaca gaauaacuua cggacaaguu gaugguaaua     3060

agguaucuaa uaaaguuaaa uuaagaccag gaaaauauua ucuacuuguu uauaaauacu     3120

caggaucagg aaacuaugag uuaaggguaa auaaauaagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  6223
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (wt)

<400>  6223
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc caugaaaaaa aauauuuuaa agauucuuau ggauaguuau ucuaaagaau      180

cuaaaauuca aacuguacgu aggguuacga guguaucacu uuuagcggua uaucuuacua      240

ugaauacuuc aaguuuaguu uuagcaaaac caauagaaaa uacuaaugau acuaguauaa      300

aaaaugugga gaaauuaaga aaugcuccaa augaagagaa uaguaaaaag guagaagaua      360

guaaaaauga uaagguagaa caugugaaaa auauagaaga ggcaaagguu gagcaaguug      420

cacccgaagu aaaaucuaaa ucaacuuuaa gaagugcuuc uagaaggcgg cgcaagagaa      480

uagcgaauac uaauucugag aaauaugauu uugaguauuu aaaugguuug agcuauacug      540

aacuuacaaa uuuaauuaaa aauauaaagu ggaaucaaau uaaugguuua uuuaauuaua      600

guacagguuc ucaaaaguuc uuuggagaua aaaaucgugu acaagcuaua auuaaugcuu      660

uacaagaaag uggaagaacu uacacugcaa augauaugaa ggguauagaa acuuucacug      720

agguuuuaag agcugguuuu uauuuagggu acuauaauga ugguuuaucu uauuuaaaug      780

auagaaacuu ccaagauaaa uguauaccug caaugauugc aauucaaaaa aauccuaacu      840

uuaagcuagg aacugcaguu caagaugaag uuauaacuuc uuuaggaaaa cuaauaggaa      900

augcuucugc uaaugcugaa guaguuaaua auuguguacc aguucuaaaa caauuuagag      960

aaaacuuaaa ucaauaugcu ccugauuacg uuaaaggaac agcuguaaau gaauuaauua     1020

aagguauuga auucgauuuu ucuggugcug cauaugaaaa agauguuaag acaaugccuu     1080

gguauggaaa aauugaucca uuuauaaaug aacuuaaggc cuuaggucua uauggaaaua     1140

uaacaagugc aacugagugg gcaucugaug uuggaauaua cuauuuaagu aaauucgguc     1200

uuuacucaac uaaccgaaau gacauaguac agucacuuga aaaggcugua gauauguaua     1260

aguaugguaa aauagccuuu guagcaaugg agagaauaac uugggauuau gaugggauug     1320

guucuaaugg uaaaaaggug gaucacgaua aguucuuaga ugaugcugaa aaacauuauc     1380

ugccaaagac auauacuuuu gauaauggaa ccuuuauuau aagagcaggg gauaagguau     1440

ccgaagaaaa aauaaaaagg cuauauuggg caucaagaga agugaagucu caauuccaua     1500

gaguaguugg caaugauaaa gcuuuagagg ugggaaaugc cgaugauguu uuaacuauga     1560

aaauauuuaa uagcccagaa gaauauaaau uuaauaccaa uauaaauggu guaagcacug     1620

auaauggugg ucuauauaua gaaccaagag ggacuuucua cacuuaugag agaacaccuc     1680

aacaaaguau auuuagucuu gaagaauugu uuagacauga auauacucac uauuuacaag     1740

cgagauaucu uguagauggu uuaugggggc aagguccauu uuaugaaaaa aauagauuaa     1800

cuugguuuga ugaagguaca gcugaauucu uugcaggauc uacccguaca ucugguguuu     1860

uaccaagaaa aucaauauua ggauauuugg cuaaggauaa aguagaucau agauacucau     1920

uaaagaagac ucuuaauuca ggguaugaug acagugauug gauguucuau aauuauggau     1980

uugcaguugc acauuaccua uaugaaaaag auaugccuac auuuauuaag augaauaaag     2040

cuauauugaa uacagaugug aaaucuuaug augaaauaau aaaaaaauua agugaugaug     2100

caaauaaaaa uacagaauau caaaaccaua uucaagaguu agcagauaaa uaucaaggag     2160

caggcauacc ucuaguauca gaugauuacu uaaaagauca uggauauaag aaagcaucug     2220

aaguauauuc ugaaauuuca aaagcugcuu cucuuacaaa cacuagugua acagcagaaa     2280

aaucucaaua uuuuaacaca uucacuuuaa gaggaacuua uacaggugaa acuucuaaag     2340

gugaauuuaa agauugggau gaaaugagua aaaaauuaga uggaacuuug gagucccuug     2400

cuaaaaauuc uuggagugga uacaaaacuu uaacagcaua cuuuacgaau uauagaguua     2460

caagcgauaa uaaaguucaa uaugauguag uuuuccaugg gguuuuaaca gauaaugcgg     2520

auauuaguaa caauaaggcu ccaauagcaa agguaacugg accaagcacu ggugcuguag     2580

gaagaaauau ugaauuuagu ggaaaagaua guaaagauga agaugguaaa auaguaucau     2640

augauuggga uuuuggcgau ggugcaacua guagaggcaa aaauucagua caugcuuaca     2700

aaaaagcagg aacauauaau guuacauuaa aaguaacuga cgauaagggu gcaacagcua     2760

cagaaagcuu uacuauagaa auaaagaacg aagauacaac aacaccuaua acuaaagaaa     2820

uggaaccuaa ugaugauaua aaagaggcua augguccaau aguugaaggu guuacuguaa     2880

aaggugauuu aaaugguucu gaugaugcug auaccuucua uuuugaugua aaagaagaug     2940

gugauguuac aauugaacuu ccuuauucag ggucaucuaa uuucacaugg uuaguuuaua     3000

aagagggaga cgaucaaaac cauauugcaa gugguauaga uaagaauaac ucaaaaguug     3060

gaacauuuaa aucuacaaaa ggaagacauu auguguuuau auauaaacac gauucugcuu     3120

caaauauauc cuauucuuua aacauaaaag gauuagguaa cgagaaauug aaggaaaaag     3180

aaaauaauga uucuucugau aaagcuacag uuauaccaaa uuucaauacc acuaugcaag     3240

guucacuuuu aggugaugau ucaagagauu auuauucuuu ugagguuaag gaagaaggcg     3300

aaguuaauau agaacuagau aaaaaggaug aauuuggugu aacauggaca cuacauccag     3360

agucaaauau uaaugacaga auaacuuacg gacaaguuga ugguaauaag guaucuaaua     3420

aaguuaaauu aagaccagga aaauauuauc uacuuguuua uaaauacuca ggaucaggaa     3480

acuaugaguu aaggguaaau aaauaaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  6224
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (wt)

<400>  6224
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc caugaaaaaa aauauuuuaa agauucuuau ggauaguuau ucuaaagaau      180

cuaaaauuca aacuguacgu aggguuacga guguaucacu uuuagcggua uaucuuacua      240

ugaauacuuc aaguuuaguu uuagcaaaac caauagaaaa uacuaaugau acaaguauaa      300

aaaaugugga gaaauuaaga aaugcuccaa augaagagaa uaguaaaaag guagaagaua      360

guaaaaauga uaagguagaa caugugaaaa auauagaaga ggcaaagguu gagcaaguug      420

cacccgaagu aaaaucuaaa ucaacuuuaa gaagugcuuc uagaaggcgg cgcaagagaa      480

uagcgaauac uaauucugag aaauaugauu uugaguauuu aaaugguuug agcuauacug      540

aacuuacaaa uuuaauuaaa aauauaaagu ggaaucaaau uaaugguuua uuuaauuaua      600

guacagguuc ucaaaaguuc uuuggagaua aaaaucgugu acaagcuaua auuaaugcuu      660

uacaagaaag uggaagaacu uacacugcaa augauaugaa ggguauagaa acuuucacug      720

agguuuuaag agcugguuuu uauuuagggu acuauaauga ugguuuaucu uauuuaaaug      780

auagaaacuu ccaagauaaa uguauaccug caaugauugc aauucaaaaa aauccuaacu      840

uuaagcuagg aacugcaguu caagaugaag uuauaacuuc uuuaggaaaa cuaauaggaa      900

augcuucugc uaaugcugaa guaguuaaua auuguguacc aguucuaaaa caauuuagag      960

aaaacuuaaa ucaauaugcu ccugauuacg uuaaaggaac agcuguaaau gaauuaauua     1020

aagguauuga guucgauuuu ucuggugcug cauaugaaaa agauguuaag acaaugccuu     1080

gguauggaaa aauugaucca uuuauaaaug aacuuaaggc cuuaggucua uauggaaaua     1140

uaacaagugc aacugagugg gcaucugaug uuggaauaua cuauuuaagu aaauucgguc     1200

uuuacucaac uaaccgaaau gacauaguac agucacuuga aaaggcugua gauauguaua     1260

aguaugguaa aauagccuuu guagcaaugg agagaauaac uugggauuau gaugggauug     1320

guucuaaugg uaaaaaggug gaucacgaua aguucuuaga ugaugcugaa aaacauuauc     1380

ugccaaagac auauacuuuu gauaauggaa ccuuuauuau aagagcaggg gauaagguau     1440

ccgaagaaaa aauaaaaagg cuauauuggg caucaagaga agugaagucu caauuccaua     1500

gaguaguugg caaugauaaa gcauuagagg ugggaaaugc cgaugauguu uuaacuauga     1560

aaauauuuaa uagcccagaa gaauauaaau uuaauaccaa uauaaauggu guaagcacug     1620

auaauggugg ucuauauaua gaaccaagag ggacuuucua cacuuaugag agaacaccuc     1680

aacaaaguau auuuagucuu gaagaauugu uuagacauga auauacucac uauuuacaag     1740

cgagauaucu uguagauggu uuaugggggc aagguccauu uuaugaaaaa aauagauuaa     1800

cuugguuuga ugaagguaca gcugaguucu uugcaggauc uacccguaca ucugguguuu     1860

uaccaagaaa aucaauauua ggauauuugg cuaaggauaa aguagaucau agauacucau     1920

uaaagaagac ucuuaauuca ggguaugaug acagugauug gauguucuau aauuauggau     1980

uugcaguugc acauuaccua uaugaaaaag auaugccuac auuuauuaag augaauaaag     2040

cuauauugaa uacagaugug aaaucuuaug augaaauaau aaaaaaauua agugaugaug     2100

caaauaaaaa uacagaauau caaaaccaua uucaagaguu agcagauaaa uaucaaggag     2160

caggcauacc ucuaguauca gaugauuacu uaaaagauca uggauauaag aaagcaucug     2220

aaguauauuc ugaaauuuca aaagcugcuu cucuuacaaa cacaagugua acagcagaaa     2280

aaucucaaua uuuuaacaca uucacuuuaa gaggaacuua uacaggugaa acuucuaaag     2340

gugaauuuaa agauugggau gaaaugagua aaaaauuaga uggaacuuug gagucccuug     2400

cuaaaaauuc uuggagugga uacaaaacuu uaacagcaua cuuuacgaau uauagaguua     2460

caagcgauaa uaaaguucaa uaugauguag uuuuccaugg gguuuuaaca gauaaugcgg     2520

auauuaguaa caauaaggcu ccaauagcaa agguaacugg accaagcacu ggugcuguag     2580

gaagaaauau ugaauuuagu ggaaaagaua guaaagauga agaugguaaa auaguaucau     2640

augauuggga uuuuggcgau ggugcaacaa guagaggcaa aaauucagua caugcuuaca     2700

aaaaagcagg aacauauaau guuacauuaa aaguaacuga cgauaagggu gcaacagcua     2760

cagagagcuu uacuauagaa auaaagaacg aagauacaac aacaccuaua acuaaagaaa     2820

uggaaccuaa ugaugauaua aaagaggcua augguccaau aguugaaggu guuacuguaa     2880

aaggugauuu aaaugguucu gaugaugcug auaccuucua uuuugaugua aaagaagaug     2940

gugauguuac aauugaacuu ccuuauucag ggucaucuaa uuucacaugg uuaguuuaua     3000

aagagggaga cgaucaaaac cauauugcaa gugguauaga uaagaauaac ucaaaaguug     3060

gaacauuuaa aucuacaaaa ggaagacauu auguguuuau auauaaacac gauucugcuu     3120

caaauauauc cuauucuuua aacauaaaag gauuagguaa cgagaaauug aaggaaaaag     3180

aaaauaauga uucuucugau aaagcuacag uuauaccaaa uuucaauacc acuaugcaag     3240

guucacuuuu aggugaugau ucaagagauu auuauucuuu ugagguuaag gaagaaggcg     3300

aaguuaauau agaacuagau aaaaaggaug aauuuggugu aacauggaca cuacauccag     3360

agucaaauau uaaugacaga auaacuuacg gacaaguuga ugguaauaag guaucuaaua     3420

aaguuaaauu aagaccagga aaauauuauc uacuuguuua uaaauacuca ggaucaggaa     3480

acuaugaguu aaggguaaau aaauaaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  6225
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  6225
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aauuuuuuaa aaauuauuuu aaauaggggg aagacuauga      120

aaaggaaaug uuuaucuaaa aggcuuaugu uagcuauaac aauggcuaca auauuuacag      180

ugaacaguac auuaccaauu uaugcagcug uagauaaaaa uaaugcaaca gcagcuguac      240

aaaaugaaag uaagagguau acaguaucau auuuaaagac uuuaaauuau uaugacuuag      300

uagauuugcu uguuaagacu gaaauugaga auuuaccaga ccuuuuucag uauaguucag      360

augcaaaaga guucuaugga aauaaaacuc guaugagcuu uaucauggau gaaauuggua      420

gaagggcacc ucaguauaca gagauagauc auaaagguau uccuacuuua guagaaguug      480

uaagagcugg auuuuacuua ggauuccaua acaaggaauu gaaugaaaua aacaagaggu      540

cuuuuaaaga aaggguaaua ccuucuauau uagcaauuca aaaaaauccu aauuuuaaac      600

uagguacuga aguucaagau aaaauaguau cugcaacagg acuuuuagcu gguaaugaaa      660

cagcgccucc agaaguugua aauaauuuua caccaauacu ucaagacugu auaaagaaua      720

uagacagaua cgcucuugau gauuuaaagu caaaagcauu auuuaauguu uuagcugcac      780

cuaccuauga uauaacugag uauuuaagag cuacuaaaga aaaaccagaa aacacuccuu      840

gguaugguaa aauagauggg uuuauaaaug aacuuaaaaa guuagcucuu uauggaaaaa      900

uaaaugauaa uaacucuugg auaauagaua acgguauaua ucauauagca ccuuuaggga      960

aguuacauag caauaauaaa auaggaauag aaacuuuaac agagguuaug aaaguuuauc     1020

cuuauuuaag uaugcaacau uuacaaucag cagaucaaau uaagcgucau uaugauucaa     1080

aagaugcuga aggaaacaaa auaccuuuag auaaguuuaa aaaggaagga aaagaaaaau     1140

acuguccaaa aacuuauaca uuugaugaug gaaaaguaau aauaaaagcu ggugcuagag     1200

uagaagaaga aaaaguuaaa agacuauacu gggcaucaaa ggaaguuaac ucucaauucu     1260

uuagaguaua cggaauagac aaaccauuag aagaagguaa uccagaugau auauuaacaa     1320

ugguuaucua caacaguccc gaagaauaua aacucaauag uguucuauac ggauaugaua     1380

cuaauaaugg ugguauguau auagagccag aaggaacuuu cuucaccuau gaaagagaag     1440

cucaagaaag cacauacaca uuagaagaau uauuuagaca ugaauauaca cauuauuugc     1500

aaggaagaua ugcaguucca ggacaauggg gaagaacaaa acuuuaugac aaugauagau     1560

uaacuuggua ugaagaaggu ggagcagaau uauuugcagg uucuacuaga acuucuggaa     1620

uauuaccaag aaagaguaua guaucaaaua uucauaauac aacaagaaau aauagauaua     1680

agcuuucaga cacuguacau ucuaaauaug gugcuaguuu ugaauucuau aauuaugcau     1740

guauguuuau ggauuauaug uauaauaaag auauggguau auuaaauaaa cuaaaugauc     1800

uugcaaaaaa uaaugauguu gauggauaug auaauuauau uagagauuua aguucuaauu     1860

augcuuuaaa ugauaaauau caagaucaua ugcaggagcg cauagauaau uaugaaaauu     1920

uaacagugcc uuuuguagcu gaugauuauu uaguaaggca ugcuuauaag aacccuaaug     1980

aaauuuauuc ugaaauaucu gaaguagcaa aauuaaagga ugcuaagagu gaaguuaaga     2040

aaucacaaua uuuuaguacc uuuacuuuga gagguaguua cacaggugga gcaucuaagg     2100

ggaaauuaga agaucaaaaa gcaaugaaua aguuuauaga ugauucacuu aagaaauuag     2160

auacguauuc uuggaguggg uauaaaacuu uaacugcuua uuucacuaau uauaaaguug     2220

acucuucaaa uagaguuacu uaugauguag uauuccacgg auauuuacca aacgaaggug     2280

auuccaaaaa uucauuaccu uauggcaaga ucaauggaac uuacaaggga acagagaaag     2340

aaaaaaucaa auucucuagu gaaggcucuu ucgauccaga ugguaaaaua guuucuuaug     2400

aaugggauuu cggagauggu aauaagagua augaggaaaa uccagagcau ucauaugaca     2460

agguaggaac uuauacagug aaauuaaaag uuacugauga caagggagaa ucuucaguau     2520

cuacuacuac ugcagaaaua aaggaucuuu cagaaaauaa acuuccaguu auauauaugc     2580

auguaccuaa auccggagcc uuaaaucaaa aaguuguuuu cuauggaaaa ggaacauaug     2640

acccagaugg aucuaucgca ggauaucaau gggacuuugg ugauggaagu gauuuuagca     2700

gugaacaaaa cccaagccau guauauacua aaaaagguga auauacugua acauuaagag     2760

uaauggauag uaguggacaa augagugaaa aaacuaugaa gauuaagauu acagauccgg     2820

uauauccaau aggcacugaa aaagaaccaa auaacaguaa agaaacugca agugguccaa     2880

uaguaccagg uauaccuguu aguggaacca uagaaaauac aagugaucaa gauuauuucu     2940

auuuugaugu uauaacacca ggagaaguaa aaauagauau aaauaaauua ggguacggag     3000

gagcuacuug gguaguauau gaugaaaaua auaaugcagu aucuuaugcc acugaugaug     3060

ggcaaaauuu aaguggaaag uuuaaggcag auaaaccagg uagauauuac auccaucuuu     3120

acauguuuaa ugguaguuau augccauaua gaauuaauau agaagguuca guaggaagau     3180

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  6226
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  6226
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aauuuuuuaa aaauuauuuu aaauaggggg aagacuauga      120

aaaggaaaug uuuaucuaaa aggcuuaugu uagcuauaac aauggcuaca auauuuacag      180

ugaacaguac auuaccaauu uaugcagcug uagauaaaaa uaaugcaaca gcagcuguac      240

aaaaugaaag uaagagguau acaguaucau auuuaaagac uuuaaauuau uaugacuuag      300

uagauuugcu uguuaagacu gaaauugaga auuuaccaga ccuuuuucag uauaguucag      360

augcaaaaga guucuaugga aauaaaacuc guaugagcuu uaucauggau gaaauuggua      420

gaagggcacc ucaguauaca gagauagauc auaaagguau uccuacuuua guagaaguug      480

uaagagcugg auuuuacuua ggauuccaua acaaggaauu gaaugaaaua aacaagaggu      540

cuuuuaaaga aaggguaaua ccuucuauau uagcaauuca aaaaaauccu aauuuuaaac      600

uagguacuga aguucaagau aaaauaguau cugcaacagg acuuuuagcu gguaaugaaa      660

cagcgccucc agaaguugua aauaauuuua caccaauacu ucaagacugu auaaagaaua      720

uagacagaua cgcucuugau gauuuaaagu caaaagcauu auuuaauguu uuagcugcac      780

cuaccuauga uauaacugag uauuuaagag cuacuaaaga aaaaccagaa aacacuccuu      840

gguaugguaa aauagauggg uuuauaaaug aacuuaaaaa guuagcucuu uauggaaaaa      900

uaaaugauaa uaacucuugg auaauagaua acgguauaua ucauauagca ccuuuaggga      960

aguuacauag caauaauaaa auaggaauag aaacuuuaac agagguuaug aaaguuuauc     1020

cuuauuuaag uaugcaacau uuacaaucag cagaucaaau uaagcgucau uaugauucaa     1080

aagaugcuga aggaaacaaa auaccuuuag auaaguuuaa aaaggaagga aaagaaaaau     1140

acuguccaaa aacuuauaca uuugaugaug gaaaaguaau aauaaaagcu ggugcuagag     1200

uagaagaaga aaaaguuaaa agacuauacu gggcaucaaa ggaaguuaac ucucaauucu     1260

uuagaguaua cggaauagac aaaccauuag aagaagguaa uccagaugau auauuaacaa     1320

ugguuaucua caacaguccc gaagaauaua aacucaauag uguucuauac ggauaugaua     1380

cuaauaaugg ugguauguau auagagccag aaggaacuuu cuucaccuau gaaagagaag     1440

cucaagaaag cacauacaca uuagaagaau uauuuagaca ugaauauaca cauuauuugc     1500

aaggaagaua ugcaguucca ggacaauggg gaagaacaaa acuuuaugac aaugauagau     1560

uaacuuggua ugaagaaggu ggagcagaau uauuugcagg uucuacuaga acuucuggaa     1620

uauuaccaag aaagaguaua guaucaaaua uucauaauac aacaagaaau aauagauaua     1680

agcugucaga cacuguacau ucuaaauaug gugcuaguuu ugaguucuau aauuaugcau     1740

guauguuuau ggauuauaug uauaauaaag auauggguau auuaaauaaa cuaaaugauc     1800

uugcaaaaaa uaaugauguu gauggauaug auaauuauau uagagauuua aguucuaauu     1860

augcuuuaaa ugauaaauau caagaucaua ugcaggagcg cauagauaau uaugaaaauu     1920

uaacagugcc uuuuguagcu gaugauuauu uaguaaggca ugcuuauaag aacccuaaug     1980

aaauuuauuc ugaaauaucu gaaguagcaa aauuaaagga ugcuaagagu gaaguuaaga     2040

aaucacaaua uuuuaguacc uuuacuuuga gagguaguua cacaggugga gcaucuaagg     2100

ggaaauuaga agaucaaaaa gcaaugaaua aguuuauaga ugauucacuu aagaaauuag     2160

auacguauuc uuggaguggg uauaaaacuu uaacugcuua uuucacuaau uauaaaguug     2220

acucuucaaa uagaguuacu uaugauguag uauuccacgg auauuuacca aacgaaggug     2280

auuccaaaaa uucauuaccu uauggcaaga ucaauggaac uuacaaggga acagagaaag     2340

aaaaaaucaa auucucuagu gaaggcucuu ucgauccaga ugguaaaaua guuucuuaug     2400

aaugggauuu cggagauggu aauaagagua augaggaaaa uccagagcau ucauaugaca     2460

agguaggaac uuauacagug aaauuaaaag uuacugauga caagggagaa ucuucaguau     2520

cuacuacuac ugcagaaaua aaggaucuuu cagaaaauaa acuuccaguu auauauaugc     2580

auguaccuaa auccggagcc uuaaaucaaa aaguuguuuu cuauggaaaa ggaacauaug     2640

acccagaugg aucuaucgca ggauaucaau gggacuuugg ugauggaagu gauuuuagca     2700

gugaacaaaa cccaagccau guauauacua aaaaagguga auauacugua acauuaagag     2760

uaauggauag uaguggacaa augagugaaa aaacuaugaa gauuaagauu acagauccgg     2820

uauauccaau aggcacugaa aaagaaccaa auaacaguaa agaaacugca agugguccaa     2880

uaguaccagg uauaccuguu aguggaacca uagaaaauac aagugaucaa gauuauuucu     2940

auuuugaugu uauaacacca ggagaaguaa aaauagauau aaauaaauua ggguacggag     3000

gagcuacuug gguaguauau gaugaaaaua auaaugcagu aucuuaugcc acugaugaug     3060

ggcaaaauuu aaguggaaag uuuaaggcag auaaaccagg uagauauuac auccaucuuu     3120

acauguuuaa ugguaguuau augccauaua gaauuaauau agaagguuca guaggaagau     3180

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  6227
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  6227
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaggaaau guuuaucuaa aaggcuuaug uuagcuauaa      120

caauggcuac aauauuuaca gugaacagua cauuaccaau uuaugcagcu guagauaaaa      180

auaaugcaac agcagcugua caaaaugaaa guaagaggua uacaguauca uauuuaaaga      240

cuuuaaauua uuaugacuua guagauuugc uuguuaagac ugaaauugag aauuuaccag      300

accuuuuuca guauaguuca gaugcaaaag aguucuaugg aaauaaaacu cguaugagcu      360

uuaucaugga ugaaauuggu agaagggcac cucaguauac agagauagau cauaaaggua      420

uuccuacuuu aguagaaguu guaagagcug gauuuuacuu aggauuccau aacaaggaau      480

ugaaugaaau aaacaagagg ucuuuuaaag aaaggguaau accuucuaua uuagcaauuc      540

aaaaaaaucc uaauuuuaaa cuagguacug aaguucaaga uaaaauagua ucugcaacag      600

gacuuuuagc ugguaaugaa acagcgccuc cagaaguugu aaauaauuuu acaccaauac      660

uucaagacug uauaaagaau auagacagau acgcucuuga ugauuuaaag ucaaaagcau      720

uauuuaaugu uuuagcugca ccuaccuaug auauaacuga guauuuaaga gcuacuaaag      780

aaaaaccaga aaacacuccu ugguauggua aaauagaugg guuuauaaau gaacuuaaaa      840

aguuagcucu uuauggaaaa auaaaugaua auaacucuug gauaauagau aacgguauau      900

aucauauagc accuuuaggg aaguuacaua gcaauaauaa aauaggaaua gaaacuuuaa      960

cagagguuau gaaaguuuau ccuuauuuaa guaugcaaca uuuacaauca gcagaucaaa     1020

uuaagcguca uuaugauuca aaagaugcug aaggaaacaa aauaccuuua gauaaguuua     1080

aaaaggaagg aaaagaaaaa uacuguccaa aaacuuauac auuugaugau ggaaaaguaa     1140

uaauaaaagc uggugcuaga guagaagaag aaaaaguuaa aagacuauac ugggcaucaa     1200

aggaaguuaa cucucaauuc uuuagaguau acggaauaga caaaccauua gaagaaggua     1260

auccagauga uauauuaaca augguuaucu acaacagucc cgaagaauau aaacucaaua     1320

guguucuaua cggauaugau acuaauaaug gugguaugua uauagagcca gaaggaacuu     1380

ucuucaccua ugaaagagaa gcucaagaaa gcacauacac auuagaagaa uuauuuagac     1440

augaauauac acauuauuug caaggaagau augcaguucc aggacaaugg ggaagaacaa     1500

aacuuuauga caaugauaga uuaacuuggu augaagaagg uggagcagaa uuauuugcag     1560

guucuacuag aacuucugga auauuaccaa gaaagaguau aguaucaaau auucauaaua     1620

caacaagaaa uaauagauau aagcuuucag acacuguaca uucuaaauau ggugcuaguu     1680

uugaauucua uaauuaugca uguauguuua uggauuauau guauaauaaa gauaugggua     1740

uauuaaauaa acuaaaugau cuugcaaaaa auaaugaugu ugauggauau gauaauuaua     1800

uuagagauuu aaguucuaau uaugcuuuaa augauaaaua ucaagaucau augcaggagc     1860

gcauagauaa uuaugaaaau uuaacagugc cuuuuguagc ugaugauuau uuaguaaggc     1920

augcuuauaa gaacccuaau gaaauuuauu cugaaauauc ugaaguagca aaauuaaagg     1980

augcuaagag ugaaguuaag aaaucacaau auuuuaguac cuuuacuuug agagguaguu     2040

acacaggugg agcaucuaag gggaaauuag aagaucaaaa agcaaugaau aaguuuauag     2100

augauucacu uaagaaauua gauacguauu cuuggagugg guauaaaacu uuaacugcuu     2160

auuucacuaa uuauaaaguu gacucuucaa auagaguuac uuaugaugua guauuccacg     2220

gauauuuacc aaacgaaggu gauuccaaaa auucauuacc uuauggcaag aucaauggaa     2280

cuuacaaggg aacagagaaa gaaaaaauca aauucucuag ugaaggcucu uucgauccag     2340

augguaaaau aguuucuuau gaaugggauu ucggagaugg uaauaagagu aaugaggaaa     2400

auccagagca uucauaugac aagguaggaa cuuauacagu gaaauuaaaa guuacugaug     2460

acaagggaga aucuucagua ucuacuacua cugcagaaau aaaggaucuu ucagaaaaua     2520

aacuuccagu uauauauaug cauguaccua aauccggagc cuuaaaucaa aaaguuguuu     2580

ucuauggaaa aggaacauau gacccagaug gaucuaucgc aggauaucaa ugggacuuug     2640

gugauggaag ugauuuuagc agugaacaaa acccaagcca uguauauacu aaaaaaggug     2700

aauauacugu aacauuaaga guaauggaua guaguggaca aaugagugaa aaaacuauga     2760

agauuaagau uacagauccg guauauccaa uaggcacuga aaaagaacca aauaacagua     2820

aagaaacugc aaguggucca auaguaccag guauaccugu uaguggaacc auagaaaaua     2880

caagugauca agauuauuuc uauuuugaug uuauaacacc aggagaagua aaaauagaua     2940

uaaauaaauu aggguacgga ggagcuacuu ggguaguaua ugaugaaaau aauaaugcag     3000

uaucuuaugc cacugaugau gggcaaaauu uaaguggaaa guuuaaggca gauaaaccag     3060

guagauauua cauccaucuu uacauguuua augguaguua uaugccauau agaauuaaua     3120

uagaagguuc aguaggaaga uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  6228
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (wt)

<400>  6228
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaggaaau guuuaucuaa aaggcuuaug uuagcuauaa      120

caauggcuac aauauuuaca gugaacagua cauuaccaau uuaugcagcu guagauaaaa      180

auaaugcaac agcagcugua caaaaugaaa guaagaggua uacaguauca uauuuaaaga      240

cuuuaaauua uuaugacuua guagauuugc uuguuaagac ugaaauugag aauuuaccag      300

accuuuuuca guauaguuca gaugcaaaag aguucuaugg aaauaaaacu cguaugagcu      360

uuaucaugga ugaaauuggu agaagggcac cucaguauac agagauagau cauaaaggua      420

uuccuacuuu aguagaaguu guaagagcug gauuuuacuu aggauuccau aacaaggaau      480

ugaaugaaau aaacaagagg ucuuuuaaag aaaggguaau accuucuaua uuagcaauuc      540

aaaaaaaucc uaauuuuaaa cuagguacug aaguucaaga uaaaauagua ucugcaacag      600

gacuuuuagc ugguaaugaa acagcgccuc cagaaguugu aaauaauuuu acaccaauac      660

uucaagacug uauaaagaau auagacagau acgcucuuga ugauuuaaag ucaaaagcau      720

uauuuaaugu uuuagcugca ccuaccuaug auauaacuga guauuuaaga gcuacuaaag      780

aaaaaccaga aaacacuccu ugguauggua aaauagaugg guuuauaaau gaacuuaaaa      840

aguuagcucu uuauggaaaa auaaaugaua auaacucuug gauaauagau aacgguauau      900

aucauauagc accuuuaggg aaguuacaua gcaauaauaa aauaggaaua gaaacuuuaa      960

cagagguuau gaaaguuuau ccuuauuuaa guaugcaaca uuuacaauca gcagaucaaa     1020

uuaagcguca uuaugauuca aaagaugcug aaggaaacaa aauaccuuua gauaaguuua     1080

aaaaggaagg aaaagaaaaa uacuguccaa aaacuuauac auuugaugau ggaaaaguaa     1140

uaauaaaagc uggugcuaga guagaagaag aaaaaguuaa aagacuauac ugggcaucaa     1200

aggaaguuaa cucucaauuc uuuagaguau acggaauaga caaaccauua gaagaaggua     1260

auccagauga uauauuaaca augguuaucu acaacagucc cgaagaauau aaacucaaua     1320

guguucuaua cggauaugau acuaauaaug gugguaugua uauagagcca gaaggaacuu     1380

ucuucaccua ugaaagagaa gcucaagaaa gcacauacac auuagaagaa uuauuuagac     1440

augaauauac acauuauuug caaggaagau augcaguucc aggacaaugg ggaagaacaa     1500

aacuuuauga caaugauaga uuaacuuggu augaagaagg uggagcagaa uuauuugcag     1560

guucuacuag aacuucugga auauuaccaa gaaagaguau aguaucaaau auucauaaua     1620

caacaagaaa uaauagauau aagcugucag acacuguaca uucuaaauau ggugcuaguu     1680

uugaguucua uaauuaugca uguauguuua uggauuauau guauaauaaa gauaugggua     1740

uauuaaauaa acuaaaugau cuugcaaaaa auaaugaugu ugauggauau gauaauuaua     1800

uuagagauuu aaguucuaau uaugcuuuaa augauaaaua ucaagaucau augcaggagc     1860

gcauagauaa uuaugaaaau uuaacagugc cuuuuguagc ugaugauuau uuaguaaggc     1920

augcuuauaa gaacccuaau gaaauuuauu cugaaauauc ugaaguagca aaauuaaagg     1980

augcuaagag ugaaguuaag aaaucacaau auuuuaguac cuuuacuuug agagguaguu     2040

acacaggugg agcaucuaag gggaaauuag aagaucaaaa agcaaugaau aaguuuauag     2100

augauucacu uaagaaauua gauacguauu cuuggagugg guauaaaacu uuaacugcuu     2160

auuucacuaa uuauaaaguu gacucuucaa auagaguuac uuaugaugua guauuccacg     2220

gauauuuacc aaacgaaggu gauuccaaaa auucauuacc uuauggcaag aucaauggaa     2280

cuuacaaggg aacagagaaa gaaaaaauca aauucucuag ugaaggcucu uucgauccag     2340

augguaaaau aguuucuuau gaaugggauu ucggagaugg uaauaagagu aaugaggaaa     2400

auccagagca uucauaugac aagguaggaa cuuauacagu gaaauuaaaa guuacugaug     2460

acaagggaga aucuucagua ucuacuacua cugcagaaau aaaggaucuu ucagaaaaua     2520

aacuuccagu uauauauaug cauguaccua aauccggagc cuuaaaucaa aaaguuguuu     2580

ucuauggaaa aggaacauau gacccagaug gaucuaucgc aggauaucaa ugggacuuug     2640

gugauggaag ugauuuuagc agugaacaaa acccaagcca uguauauacu aaaaaaggug     2700

aauauacugu aacauuaaga guaauggaua guaguggaca aaugagugaa aaaacuauga     2760

agauuaagau uacagauccg guauauccaa uaggcacuga aaaagaacca aauaacagua     2820

aagaaacugc aaguggucca auaguaccag guauaccugu uaguggaacc auagaaaaua     2880

caagugauca agauuauuuc uauuuugaug uuauaacacc aggagaagua aaaauagaua     2940

uaaauaaauu aggguacgga ggagcuacuu ggguaguaua ugaugaaaau aauaaugcag     3000

uaucuuaugc cacugaugau gggcaaaauu uaaguggaaa guuuaaggca gauaaaccag     3060

guagauauua cauccaucuu uacauguuua augguaguua uaugccauau agaauuaaua     3120

uagaagguuc aguaggaaga uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  6229
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (wt)

<400>  6229
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc cguacaaaau gaaaguaaga gguauacagu aucauauuua aagacuuuaa      180

auuauuauga cuuaguagau uugcuuguua agacugaaau ugagaauuua ccagaccuuu      240

uucaguauag uucagaugca aaagaguucu auggaaauaa aacucguaug agcuuuauca      300

uggaugaaau ugguagaagg gcaccucagu auacagagau agaucauaaa gguauuccua      360

cuuuaguaga aguuguaaga gcuggauuuu acuuaggauu ccauaacaag gaauugaaug      420

aaauaaacaa gaggucuuuu aaagaaaggg uaauaccuuc uauauuagca auucaaaaaa      480

auccuaauuu uaaacuaggu acugaaguuc aagauaaaau aguaucugca acaggacuuu      540

uagcugguaa ugaaacagcg ccuccagaag uuguaaauaa uuuuacacca auacuucaag      600

acuguauaaa gaauauagac agauacgcuc uugaugauuu aaagucaaaa gcauuauuua      660

auguuuuagc ugcaccuacc uaugauauaa cugaguauuu aagagcuacu aaagaaaaac      720

cagaaaacac uccuugguau gguaaaauag auggguuuau aaaugaacuu aaaaaguuag      780

cucuuuaugg aaaaauaaau gauaauaacu cuuggauaau agauaacggu auauaucaua      840

uagcaccuuu agggaaguua cauagcaaua auaaaauagg aauagaaacu uuaacagagg      900

uuaugaaagu uuauccuuau uuaaguaugc aacauuuaca aucagcagau caaauuaagc      960

gucauuauga uucaaaagau gcugaaggaa acaaaauacc uuuagauaag uuuaaaaagg     1020

aaggaaaaga aaaauacugu ccaaaaacuu auacauuuga ugauggaaaa guaauaauaa     1080

aagcuggugc uagaguagaa gaagaaaaag uuaaaagacu auacugggca ucaaaggaag     1140

uuaacucuca auucuuuaga guauacggaa uagacaaacc auuagaagaa gguaauccag     1200

augauauauu aacaaugguu aucuacaaca gucccgaaga auauaaacuc aauaguguuc     1260

uauacggaua ugauacuaau aaugguggua uguauauaga gccagaagga acuuucuuca     1320

ccuaugaaag agaagcucaa gaaagcacau acacauuaga agaauuauuu agacaugaau     1380

auacacauua uuugcaagga agauaugcag uuccaggaca auggggaaga acaaaacuuu     1440

augacaauga uagauuaacu ugguaugaag aagguggagc agaauuauuu gcagguucua     1500

cuagaacuuc uggaauauua ccaagaaaga guauaguauc aaauauucau aauacaacaa     1560

gaaauaauag auauaagcuu ucagacacug uacauucuaa auauggugcu aguuuugaau     1620

ucuauaauua ugcauguaug uuuauggauu auauguauaa uaaagauaug gguauauuaa     1680

auaaacuaaa ugaucuugca aaaaauaaug auguugaugg auaugauaau uauauuagag     1740

auuuaaguuc uaauuaugcu uuaaaugaua aauaucaaga ucauaugcag gagcgcauag     1800

auaauuauga aaauuuaaca gugccuuuug uagcugauga uuauuuagua aggcaugcuu     1860

auaagaaccc uaaugaaauu uauucugaaa uaucugaagu agcaaaauua aaggaugcua     1920

agagugaagu uaagaaauca caauauuuua guaccuuuac uuugagaggu aguuacacag     1980

guggagcauc uaaggggaaa uuagaagauc aaaaagcaau gaauaaguuu auagaugauu     2040

cacuuaagaa auuagauacg uauucuugga guggguauaa aacuuuaacu gcuuauuuca     2100

cuaauuauaa aguugacucu ucaaauagag uuacuuauga uguaguauuc cacggauauu     2160

uaccaaacga aggugauucc aaaaauucau uaccuuaugg caagaucaau ggaacuuaca     2220

agggaacaga gaaagaaaaa aucaaauucu cuagugaagg cucuuucgau ccagauggua     2280

aaauaguuuc uuaugaaugg gauuucggag augguaauaa gaguaaugag gaaaauccag     2340

agcauucaua ugacaaggua ggaacuuaua cagugaaauu aaaaguuacu gaugacaagg     2400

gagaaucuuc aguaucuacu acuacugcag aaauaaagga ucuuucagaa aauaaacuuc     2460

caguuauaua uaugcaugua ccuaaauccg gagccuuaaa ucaaaaaguu guuuucuaug     2520

gaaaaggaac auaugaccca gauggaucua ucgcaggaua ucaaugggac uuuggugaug     2580

gaagugauuu uagcagugaa caaaacccaa gccauguaua uacuaaaaaa ggugaauaua     2640

cuguaacauu aagaguaaug gauaguagug gacaaaugag ugaaaaaacu augaagauua     2700

agauuacaga uccgguauau ccaauaggca cugaaaaaga accaaauaac aguaaagaaa     2760

cugcaagugg uccaauagua ccagguauac cuguuagugg aaccauagaa aauacaagug     2820

aucaagauua uuucuauuuu gauguuauaa caccaggaga aguaaaaaua gauauaaaua     2880

aauuagggua cggaggagcu acuuggguag uauaugauga aaauaauaau gcaguaucuu     2940

augccacuga ugaugggcaa aauuuaagug gaaaguuuaa ggcagauaaa ccagguagau     3000

auuacaucca ucuuuacaug uuuaauggua guuauaugcc auauagaauu aauauagaag     3060

guucaguagg aagauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6230
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (wt)

<400>  6230
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc cguacaaaau gaaaguaaga gguauacagu aucauauuua aagacuuuaa      180

auuauuauga cuuaguagau uugcuuguua agacugaaau ugagaauuua ccagaccuuu      240

uucaguauag uucagaugca aaagaguucu auggaaauaa aacucguaug agcuuuauca      300

uggaugaaau ugguagaagg gcaccucagu auacagagau agaucauaaa gguauuccua      360

cuuuaguaga aguuguaaga gcuggauuuu acuuaggauu ccauaacaag gaauugaaug      420

aaauaaacaa gaggucuuuu aaagaaaggg uaauaccuuc uauauuagca auucaaaaaa      480

auccuaauuu uaaacuaggu acugaaguuc aagauaaaau aguaucugca acaggacuuu      540

uagcugguaa ugaaacagcg ccuccagaag uuguaaauaa uuuuacacca auacuucaag      600

acuguauaaa gaauauagac agauacgcuc uugaugauuu aaagucaaaa gcauuauuua      660

auguuuuagc ugcaccuacc uaugauauaa cugaguauuu aagagcuacu aaagaaaaac      720

cagaaaacac uccuugguau gguaaaauag auggguuuau aaaugaacuu aaaaaguuag      780

cucuuuaugg aaaaauaaau gauaauaacu cuuggauaau agauaacggu auauaucaua      840

uagcaccuuu agggaaguua cauagcaaua auaaaauagg aauagaaacu uuaacagagg      900

uuaugaaagu uuauccuuau uuaaguaugc aacauuuaca aucagcagau caaauuaagc      960

gucauuauga uucaaaagau gcugaaggaa acaaaauacc uuuagauaag uuuaaaaagg     1020

aaggaaaaga aaaauacugu ccaaaaacuu auacauuuga ugauggaaaa guaauaauaa     1080

aagcuggugc uagaguagaa gaagaaaaag uuaaaagacu auacugggca ucaaaggaag     1140

uuaacucuca auucuuuaga guauacggaa uagacaaacc auuagaagaa gguaauccag     1200

augauauauu aacaaugguu aucuacaaca gucccgaaga auauaaacuc aauaguguuc     1260

uauacggaua ugauacuaau aaugguggua uguauauaga gccagaagga acuuucuuca     1320

ccuaugaaag agaagcucaa gaaagcacau acacauuaga agaauuauuu agacaugaau     1380

auacacauua uuugcaagga agauaugcag uuccaggaca auggggaaga acaaaacuuu     1440

augacaauga uagauuaacu ugguaugaag aagguggagc agaauuauuu gcagguucua     1500

cuagaacuuc uggaauauua ccaagaaaga guauaguauc aaauauucau aauacaacaa     1560

gaaauaauag auauaagcug ucagacacug uacauucuaa auauggugcu aguuuugagu     1620

ucuauaauua ugcauguaug uuuauggauu auauguauaa uaaagauaug gguauauuaa     1680

auaaacuaaa ugaucuugca aaaaauaaug auguugaugg auaugauaau uauauuagag     1740

auuuaaguuc uaauuaugcu uuaaaugaua aauaucaaga ucauaugcag gagcgcauag     1800

auaauuauga aaauuuaaca gugccuuuug uagcugauga uuauuuagua aggcaugcuu     1860

auaagaaccc uaaugaaauu uauucugaaa uaucugaagu agcaaaauua aaggaugcua     1920

agagugaagu uaagaaauca caauauuuua guaccuuuac uuugagaggu aguuacacag     1980

guggagcauc uaaggggaaa uuagaagauc aaaaagcaau gaauaaguuu auagaugauu     2040

cacuuaagaa auuagauacg uauucuugga guggguauaa aacuuuaacu gcuuauuuca     2100

cuaauuauaa aguugacucu ucaaauagag uuacuuauga uguaguauuc cacggauauu     2160

uaccaaacga aggugauucc aaaaauucau uaccuuaugg caagaucaau ggaacuuaca     2220

agggaacaga gaaagaaaaa aucaaauucu cuagugaagg cucuuucgau ccagauggua     2280

aaauaguuuc uuaugaaugg gauuucggag augguaauaa gaguaaugag gaaaauccag     2340

agcauucaua ugacaaggua ggaacuuaua cagugaaauu aaaaguuacu gaugacaagg     2400

gagaaucuuc aguaucuacu acuacugcag aaauaaagga ucuuucagaa aauaaacuuc     2460

caguuauaua uaugcaugua ccuaaauccg gagccuuaaa ucaaaaaguu guuuucuaug     2520

gaaaaggaac auaugaccca gauggaucua ucgcaggaua ucaaugggac uuuggugaug     2580

gaagugauuu uagcagugaa caaaacccaa gccauguaua uacuaaaaaa ggugaauaua     2640

cuguaacauu aagaguaaug gauaguagug gacaaaugag ugaaaaaacu augaagauua     2700

agauuacaga uccgguauau ccaauaggca cugaaaaaga accaaauaac aguaaagaaa     2760

cugcaagugg uccaauagua ccagguauac cuguuagugg aaccauagaa aauacaagug     2820

aucaagauua uuucuauuuu gauguuauaa caccaggaga aguaaaaaua gauauaaaua     2880

aauuagggua cggaggagcu acuuggguag uauaugauga aaauaauaau gcaguaucuu     2940

augccacuga ugaugggcaa aauuuaagug gaaaguuuaa ggcagauaaa ccagguagau     3000

auuacaucca ucuuuacaug uuuaauggua guuauaugcc auauagaauu aauauagaag     3060

guucaguagg aagauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6231
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (wt)

<400>  6231
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc caugaaaagg aaauguuuau cuaaaaggcu uauguuagcu auaacaaugg      180

cuacaauauu uacagugaac aguacauuac caauuuaugc agcuguagau aaaaauaaug      240

caacagcagc uagaaggcgg cgcaagagag uacaaaauga aaguaagagg uauacaguau      300

cauauuuaaa gacuuuaaau uauuaugacu uaguagauuu gcuuguuaag acugaaauug      360

agaauuuacc agaccuuuuu caguauaguu cagaugcaaa agaguucuau ggaaauaaaa      420

cucguaugag cuuuaucaug gaugaaauug guagaagggc accucaguau acagagauag      480

aucauaaagg uauuccuacu uuaguagaag uuguaagagc uggauuuuac uuaggauucc      540

auaacaagga auugaaugaa auaaacaaga ggucuuuuaa agaaagggua auaccuucua      600

uauuagcaau ucaaaaaaau ccuaauuuua aacuagguac ugaaguucaa gauaaaauag      660

uaucugcaac aggacuuuua gcugguaaug aaacagcgcc uccagaaguu guaaauaauu      720

uuacaccaau acuucaagac uguauaaaga auauagacag auacgcucuu gaugauuuaa      780

agucaaaagc auuauuuaau guuuuagcug caccuaccua ugauauaacu gaguauuuaa      840

gagcuacuaa agaaaaacca gaaaacacuc cuugguaugg uaaaauagau ggguuuauaa      900

augaacuuaa aaaguuagcu cuuuauggaa aaauaaauga uaauaacucu uggauaauag      960

auaacgguau auaucauaua gcaccuuuag ggaaguuaca uagcaauaau aaaauaggaa     1020

uagaaacuuu aacagagguu augaaaguuu auccuuauuu aaguaugcaa cauuuacaau     1080

cagcagauca aauuaagcgu cauuaugauu caaaagaugc ugaaggaaac aaaauaccuu     1140

uagauaaguu uaaaaaggaa ggaaaagaaa aauacugucc aaaaacuuau acauuugaug     1200

auggaaaagu aauaauaaaa gcuggugcua gaguagaaga agaaaaaguu aaaagacuau     1260

acugggcauc aaaggaaguu aacucucaau ucuuuagagu auacggaaua gacaaaccau     1320

uagaagaagg uaauccagau gauauauuaa caaugguuau cuacaacagu cccgaagaau     1380

auaaacucaa uaguguucua uacggauaug auacuaauaa uggugguaug uauauagagc     1440

cagaaggaac uuucuucacc uaugaaagag aagcucaaga aagcacauac acauuagaag     1500

aauuauuuag acaugaauau acacauuauu ugcaaggaag auaugcaguu ccaggacaau     1560

ggggaagaac aaaacuuuau gacaaugaua gauuaacuug guaugaagaa gguggagcag     1620

aauuauuugc agguucuacu agaacuucug gaauauuacc aagaaagagu auaguaucaa     1680

auauucauaa uacaacaaga aauaauagau auaagcuuuc agacacugua cauucuaaau     1740

auggugcuag uuuugaauuc uauaauuaug cauguauguu uauggauuau auguauaaua     1800

aagauauggg uauauuaaau aaacuaaaug aucuugcaaa aaauaaugau guugauggau     1860

augauaauua uauuagagau uuaaguucua auuaugcuuu aaaugauaaa uaucaagauc     1920

auaugcagga gcgcauagau aauuaugaaa auuuaacagu gccuuuugua gcugaugauu     1980

auuuaguaag gcaugcuuau aagaacccua augaaauuua uucugaaaua ucugaaguag     2040

caaaauuaaa ggaugcuaag agugaaguua agaaaucaca auauuuuagu accuuuacuu     2100

ugagagguag uuacacaggu ggagcaucua aggggaaauu agaagaucaa aaagcaauga     2160

auaaguuuau agaugauuca cuuaagaaau uagauacgua uucuuggagu ggguauaaaa     2220

cuuuaacugc uuauuucacu aauuauaaag uugacucuuc aaauagaguu acuuaugaug     2280

uaguauucca cggauauuua ccaaacgaag gugauuccaa aaauucauua ccuuauggca     2340

agaucaaugg aacuuacaag ggaacagaga aagaaaaaau caaauucucu agugaaggcu     2400

cuuucgaucc agaugguaaa auaguuucuu augaauggga uuucggagau gguaauaaga     2460

guaaugagga aaauccagag cauucauaug acaagguagg aacuuauaca gugaaauuaa     2520

aaguuacuga ugacaaggga gaaucuucag uaucuacuac uacugcagaa auaaaggauc     2580

uuucagaaaa uaaacuucca guuauauaua ugcauguacc uaaauccgga gccuuaaauc     2640

aaaaaguugu uuucuaugga aaaggaacau augacccaga uggaucuauc gcaggauauc     2700

aaugggacuu uggugaugga agugauuuua gcagugaaca aaacccaagc cauguauaua     2760

cuaaaaaagg ugaauauacu guaacauuaa gaguaaugga uaguagugga caaaugagug     2820

aaaaaacuau gaagauuaag auuacagauc cgguauaucc aauaggcacu gaaaaagaac     2880

caaauaacag uaaagaaacu gcaagugguc caauaguacc agguauaccu guuaguggaa     2940

ccauagaaaa uacaagugau caagauuauu ucuauuuuga uguuauaaca ccaggagaag     3000

uaaaaauaga uauaaauaaa uuaggguacg gaggagcuac uuggguagua uaugaugaaa     3060

auaauaaugc aguaucuuau gccacugaug augggcaaaa uuuaagugga aaguuuaagg     3120

cagauaaacc agguagauau uacauccauc uuuacauguu uaaugguagu uauaugccau     3180

auagaauuaa uauagaaggu ucaguaggaa gauaaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  6232
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (wt)

<400>  6232
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa ccuuuauuuc ccuucuuuuu cucuuuagcu      120

cggcuuauuc caugaaaagg aaauguuuau cuaaaaggcu uauguuagcu auaacaaugg      180

cuacaauauu uacagugaac aguacauuac caauuuaugc agcuguagau aaaaauaaug      240

caacagcagc uagaaggcgg cgcaagagag uacaaaauga aaguaagagg uauacaguau      300

cauauuuaaa gacuuuaaau uauuaugacu uaguagauuu gcuuguuaag acugaaauug      360

agaauuuacc agaccuuuuu caguauaguu cagaugcaaa agaguucuau ggaaauaaaa      420

cucguaugag cuuuaucaug gaugaaauug guagaagggc accucaguau acagagauag      480

aucauaaagg uauuccuacu uuaguagaag uuguaagagc uggauuuuac uuaggauucc      540

auaacaagga auugaaugaa auaaacaaga ggucuuuuaa agaaagggua auaccuucua      600

uauuagcaau ucaaaaaaau ccuaauuuua aacuagguac ugaaguucaa gauaaaauag      660

uaucugcaac aggacuuuua gcugguaaug aaacagcgcc uccagaaguu guaaauaauu      720

uuacaccaau acuucaagac uguauaaaga auauagacag auacgcucuu gaugauuuaa      780

agucaaaagc auuauuuaau guuuuagcug caccuaccua ugauauaacu gaguauuuaa      840

gagcuacuaa agaaaaacca gaaaacacuc cuugguaugg uaaaauagau ggguuuauaa      900

augaacuuaa aaaguuagcu cuuuauggaa aaauaaauga uaauaacucu uggauaauag      960

auaacgguau auaucauaua gcaccuuuag ggaaguuaca uagcaauaau aaaauaggaa     1020

uagaaacuuu aacagagguu augaaaguuu auccuuauuu aaguaugcaa cauuuacaau     1080

cagcagauca aauuaagcgu cauuaugauu caaaagaugc ugaaggaaac aaaauaccuu     1140

uagauaaguu uaaaaaggaa ggaaaagaaa aauacugucc aaaaacuuau acauuugaug     1200

auggaaaagu aauaauaaaa gcuggugcua gaguagaaga agaaaaaguu aaaagacuau     1260

acugggcauc aaaggaaguu aacucucaau ucuuuagagu auacggaaua gacaaaccau     1320

uagaagaagg uaauccagau gauauauuaa caaugguuau cuacaacagu cccgaagaau     1380

auaaacucaa uaguguucua uacggauaug auacuaauaa uggugguaug uauauagagc     1440

cagaaggaac uuucuucacc uaugaaagag aagcucaaga aagcacauac acauuagaag     1500

aauuauuuag acaugaauau acacauuauu ugcaaggaag auaugcaguu ccaggacaau     1560

ggggaagaac aaaacuuuau gacaaugaua gauuaacuug guaugaagaa gguggagcag     1620

aauuauuugc agguucuacu agaacuucug gaauauuacc aagaaagagu auaguaucaa     1680

auauucauaa uacaacaaga aauaauagau auaagcuguc agacacugua cauucuaaau     1740

auggugcuag uuuugaguuc uauaauuaug cauguauguu uauggauuau auguauaaua     1800

aagauauggg uauauuaaau aaacuaaaug aucuugcaaa aaauaaugau guugauggau     1860

augauaauua uauuagagau uuaaguucua auuaugcuuu aaaugauaaa uaucaagauc     1920

auaugcagga gcgcauagau aauuaugaaa auuuaacagu gccuuuugua gcugaugauu     1980

auuuaguaag gcaugcuuau aagaacccua augaaauuua uucugaaaua ucugaaguag     2040

caaaauuaaa ggaugcuaag agugaaguua agaaaucaca auauuuuagu accuuuacuu     2100

ugagagguag uuacacaggu ggagcaucua aggggaaauu agaagaucaa aaagcaauga     2160

auaaguuuau agaugauuca cuuaagaaau uagauacgua uucuuggagu ggguauaaaa     2220

cuuuaacugc uuauuucacu aauuauaaag uugacucuuc aaauagaguu acuuaugaug     2280

uaguauucca cggauauuua ccaaacgaag gugauuccaa aaauucauua ccuuauggca     2340

agaucaaugg aacuuacaag ggaacagaga aagaaaaaau caaauucucu agugaaggcu     2400

cuuucgaucc agaugguaaa auaguuucuu augaauggga uuucggagau gguaauaaga     2460

guaaugagga aaauccagag cauucauaug acaagguagg aacuuauaca gugaaauuaa     2520

aaguuacuga ugacaaggga gaaucuucag uaucuacuac uacugcagaa auaaaggauc     2580

uuucagaaaa uaaacuucca guuauauaua ugcauguacc uaaauccgga gccuuaaauc     2640

aaaaaguugu uuucuaugga aaaggaacau augacccaga uggaucuauc gcaggauauc     2700

aaugggacuu uggugaugga agugauuuua gcagugaaca aaacccaagc cauguauaua     2760

cuaaaaaagg ugaauauacu guaacauuaa gaguaaugga uaguagugga caaaugagug     2820

aaaaaacuau gaagauuaag auuacagauc cgguauaucc aauaggcacu gaaaaagaac     2880

caaauaacag uaaagaaacu gcaagugguc caauaguacc agguauaccu guuaguggaa     2940

ccauagaaaa uacaagugau caagauuauu ucuauuuuga uguuauaaca ccaggagaag     3000

uaaaaauaga uauaaauaaa uuaggguacg gaggagcuac uuggguagua uaugaugaaa     3060

auaauaaugc aguaucuuau gccacugaug augggcaaaa uuuaagugga aaguuuaagg     3120

cagauaaacc agguagauau uacauccauc uuuacauguu uaaugguagu uauaugccau     3180

auagaauuaa uauagaaggu ucaguaggaa gauaaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  6233
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (wt)

<400>  6233
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuauuugc cugccuccug ggagcagcuu      120

uugccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc uuugaagugg uaccagagca uaaggccacc guacccuucc uaugguuacg      240

agcccauggg uggauggcug caccaccaaa ucauccccgu gcugucccaa cagcaccccc      300

cgacucacac ccugcagccu caucaccaca ucccaguggu gccagcucag cagcccguga      360

ucccccagca accaaugaug cccguuccug gccaacacuc caugacucca auccaacacc      420

accagccaaa ccucccuccg cccgcccagc agcccuacca gccccagccu guucagccac      480

agccucacca gcccaugcag ccccagccac cugugcaccc caugcagccc cugccgccac      540

agccaccucu gccuccgaug uuccccaugc agccccugcc ucccaugcuu ccugaucuga      600

cucuggaagc uuggccauca acagacaaga ccaagcggga ggaaguggau uaaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  6234
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (wt)

<400>  6234
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuauuugc cugccuccug ggagcagcuu      120

uugccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc uuugaagugg uaccagagca uaaggccacc guacccuucc uaugguuacg      240

agcccauggg uggauggcug caccaccaaa ucauccccgu gcugucccaa cagcaccccc      300

cgacucacac ccugcagccu caucaccaca ucccaguggu gccagcucag cagcccguga      360

ucccccagca accaaugaug cccguuccug gccaacacuc caugacucca auccaacacc      420

accagccaaa ccucccuccg cccgcccagc agcccuacca gccccagccu guucagccac      480

agccucacca gcccaugcag ccccagccac cugugcaccc caugcagccc cugccgccac      540

agccaccucu gccuccgaug uuccccaugc agccccugcc ucccaugcuu ccugaucuga      600

cucuggaagc auggccauca acagacaaga ccaagcggga ggaaguggau uaaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  6235
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (wt)

<400>  6235
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccuuugaagu gguaccagag cauaaggcca ccguacccuu      180

ccuaugguua cgagcccaug gguggauggu aaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  6236
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (wt)

<400>  6236
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccuuugaagu gguaccagag cauaaggcca ccucccaugc      180

uuccugaucu gacucuggaa gcuuggccau caacagacaa gaccaagcgg gaggaagugg      240

auuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  6237
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (wt)

<400>  6237
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccuuugaagu gguaccagag cauaaggcca ccucccaugc      180

uuccugaucu gacucuggaa gcauggccau caacagacaa gaccaagcgg gaggaagugg      240

auuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  6238
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (wt)

<400>  6238
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg cgccccgaac ccucguccug cuacucucgg      120

gggcucuggc ccugacccag accugggcga ugccucuacc accucauccu gggcacccug      180

guuauaucaa cuucagcuau gaggugcuua ccccuuugaa gugguaccag agcauaaggc      240

caccguaccc uuccuauggu uacgagccca uggguggaug guaaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  6239
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (wt)

<400>  6239
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg cgccccgaac ccucguccug cuacucucgg      120

gggcucuggc ccugacccag accugggcga ugccucuacc accucauccu gggcacccug      180

guuauaucaa cuucagcuau gaggugcuua ccccuuugaa gugguaccag agcauaaggc      240

caccucccau gcuuccugau cugacucugg aagcauggcc aucaacagac aagaccaagc      300

gggaggaagu ggauuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  6240
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (wt)

<400>  6240
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc cugccuugug ggagcagcuu      120

uugccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcucacccc uuugaagugg uaccagagca ugauaagacc accauacucu uccuaugguu      240

acgagcccau ggguggaugg cugcaccacc aaaucauccc cguggugucc caacagcacc      300

cccugacuca cacccugcag ucucaucacc acaucccagu ggugccagcu cagcagccca      360

ggguccgcca gcaagcacug augccuguuc cuggccagca auccaugacu ccaacccaac      420

accaucagcc aaaccucccu cugccugccc agcagcccuu ccagccccag ccuguucagc      480

cacagccuca ccagcccaug cagccccagc caccugugca acccaugcag ccccugcugc      540

cacagccacc ucugccucca auguuccccc ugcggccccu gccccccaua cuuccugauc      600

ugcaucugga agcuuggcca gcaacagaca agaccaagca ggaggaagug gauuaaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  6241
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (wt)

<400>  6241
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc cugccuugug ggagcagcuu      120

uugccaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcucacccc uuugaagugg uaccagagca ugauaagacc accauacucu uccuaugguu      240

acgagcccau ggguggaugg cugcaccacc aaaucauccc cguggugucc caacagcacc      300

cccugacuca cacccugcag ucucaucacc acaucccagu ggugccagcu cagcagccca      360

ggguccgcca gcaagcacug augccuguuc cuggccagca auccaugacu ccaacccaac      420

accaucagcc aaaccucccu cugccugccc agcagcccuu ccagccccag ccuguucagc      480

cacagccuca ccagcccaug cagccccagc caccugugca acccaugcag ccccugcugc      540

cacagccacc ucugccucca auguuccccc ugcggccccu gccccccaua cuuccugauc      600

ugcaucugga agcauggcca gcaacagaca agaccaagca ggaggaagug gauuaaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  6242
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (wt)

<400>  6242
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcucacc ccuuugaagu gguaccagag caugauaaga ccaccauacu      180

cuuccuaugg uuacgagccc auggguggau gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6243
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (wt)

<400>  6243
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcucacc ccuuugaagu gguaccagag caugauaaga ccacccccca      180

uacuuccuga ucugcaucug gaagcuuggc cagcaacaga caagaccaag caggaggaag      240

uggauuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6244
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (wt)

<400>  6244
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcucacc ccuuugaagu gguaccagag caugauaaga ccacccccca      180

uacuuccuga ucugcaucug gaagcauggc cagcaacaga caagaccaag caggaggaag      240

uggauuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6245
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (wt)

<400>  6245
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg cgccccgaac ccucguccug cuacucucgg      120

gggcucuggc ccugacccag accugggcga ugccucuacc accucauccu gggcacccug      180

guuauaucaa cuucagcuau gaggugcuca ccccuuugaa gugguaccag agcaugauaa      240

gaccaccaua cucuuccuau gguuacgagc ccaugggugg augguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6246
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (wt)

<400>  6246
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg cgccccgaac ccucguccug cuacucucgg      120

gggcucuggc ccugacccag accugggcga ugccucuacc accucauccu gggcacccug      180

guuauaucaa cuucagcuau gaggugcuca ccccuuugaa gugguaccag agcaugauaa      240

gaccaccccc cauacuuccu gaucugcauc uggaagcaug gccagcaaca gacaagacca      300

agcaggagga aguggauuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6247
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (wt)

<400>  6247
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccguacacu uccuaugggu      240

acgaacccau ggguggaugg cugcaccacc aaaucauacc cguggugucg cagcagacuc      300

cccagaguca ugcccuucag ccucaucacc acauccccau ggugccagcu caacagcccg      360

ggauccccca gcagccaaug augccacuuc cuggccaaca cuccaugacu ccaacccaac      420

accaccagcc aaaccucccu cugcccgccc agcagcccuu ccagccccag cccguccagc      480

cccagccuca ccagccccug cagccccagu cacccaugca ccccauccag cccuugcugc      540

cacagccacc ucugccuccg auguucucca ugcagucucu gcuuccugac cugccucugg      600

aagcuuggcc agcaacagac aagaccaagc gggaggaagu ggauuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6248
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (wt)

<400>  6248
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccguacacu uccuaugggu      240

acgaacccau ggguggaugg cugcaccacc aaaucauacc cguggugucg cagcagacuc      300

cccagaguca ugcccuucag ccucaucacc acauccccau ggugccagcu caacagcccg      360

ggauccccca gcagccaaug augccacuuc cuggccaaca cuccaugacu ccaacccaac      420

accaccagcc aaaccucccu cugcccgccc agcagcccuu ccagccccag cccguccagc      480

cccagccuca ccagccccug cagccccagu cacccaugca ccccauccag cccuugcugc      540

cacagccacc ucugccuccg auguucucca ugcagucucu gcuuccugac cugccucugg      600

aagcauggcc agcaacagac aagaccaagc gggaggaagu ggauuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6249
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (wt)

<400>  6249
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccucugaagu gguaccagaa caugauaaga cauccguaca      180

cuuccuaugg guacgaaccc auggguggau gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6250
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (wt)

<400>  6250
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccucugaagu gguaccagaa caugauaaga cauccgucuc      180

ugcuuccuga ccugccucug gaagcuuggc cagcaacaga caagaccaag cgggaggaag      240

uggauuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6251
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (wt)

<400>  6251
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccucugaagu gguaccagaa caugauaaga cauccgucuc      180

ugcuuccuga ccugccucug gaagcauggc cagcaacaga caagaccaag cgggaggaag      240

uggauuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6252
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (wt)

<400>  6252
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg cgccccgaac ccucguccug cuacucucgg      120

gggcucuggc ccugacccag accugggcga ugccucuacc accucauccu gggcacccug      180

guuauaucaa cuucagcuau gaggugcuua ccccucugaa gugguaccag aacaugauaa      240

gacauccgua cacuuccuau ggguacgaac ccaugggugg augguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6253
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (wt)

<400>  6253
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg cgccccgaac ccucguccug cuacucucgg      120

gggcucuggc ccugacccag accugggcga ugccucuacc accucauccu gggcacccug      180

guuauaucaa cuucagcuau gaggugcuua ccccucugaa gugguaccag aacaugauaa      240

gacauccguc ucugcuuccu gaccugccuc uggaagcaug gccagcaaca gacaagacca      300

agcgggagga aguggauuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6254
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (wt)

<400>  6254
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuauauaa      180

gacauccgua cacuuccuau ggguacgaac ccaugggugg auggcugcac caccaaauca      240

uacccguggu gucgcagcag acuccccaga gucaugcccu ucagccucau caccacaucc      300

ccauggugcc agcucaacag cccgggaucc cccagcagcc aaugaugcca cuuccuggcc      360

aacacuccau gacuccaacc caacaccacc agccaaaccu cccucugccc gcccagcagc      420

ccuuccagcc ccagcccguc cagccccagc cucaccagcc ccugcagccc cagucaccca      480

ugcaccccau ccagcccuug cugccacagc caccucugcc uccgauguuc uccaugcagu      540

cucugcuucc ugaccugccu cuggaagcuu ggccagcaac agacaagacc aagcgggagg      600

aaguggauua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  6255
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (wt)

<400>  6255
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuucuuugc cugccuuuug ggagcauccc      120

uugcuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccguacacu uccuaugggu      240

acgaacccau ggguggaugg cugcaccacc aaaucauacc cguggugucg cagcagacuc      300

cccagaguca ugcccuucag ccucaucacc acauccccau ggugccagcu caacagcccg      360

ggauccccca gcagccaaug augccacuuc cuggccaaca cuccaugacu ccaacccaac      420

accaccagcc aaaccucccu cugcccgccc agcagcccuu ccagccccag cccguccagc      480

cccagccuca ccagccccug cagccccagu cacccaugca ccccauccag cccuugcugc      540

cacagccacc ucugccuccg auguucucca ugcagucucu gcuuccugac cugccucugg      600

aagcuuggcc agcaacagac aagaccaagc gggaggaagu ggauuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6256
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (wt)

<400>  6256
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccgucucug cuuccugacc      240

ugccucugga agcuuggcca gcaacagaca agaccaagcg ggaggaagug gauuaaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  6257
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (wt)

<400>  6257
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

acuuauacuu ggaggcuauc cguauugaca ggacugcauu cgugcuuacc ccucugaagu      240

gguaccagaa caugauaaga cauccguaca cuuccuaugg uuacgaaccc auggguggau      300

ggcugcacca ccaaaucauu cccguggugu cgcagcagac uccccagagu caugcccuuc      360

agccucauca ccacaucccc auggugccag cucaacagcc cgggaucccc cagcagccaa      420

ugaugccacu uccuggccaa cacuccauga cuccaaccca acaccaccag ccaaaccucc      480

cucugcccgc ccagcagccc uuccagcccc agcccgucca gccccagccu caccagcccc      540

ugcagcccca gucacccaug caccccaucc agcccuugcu gccacagcca ccucugccuc      600

cgauguucuc caugcagucu cugcuuccug accugccucu ggaagcuugg ccagcaacag      660

acaagaccaa gcgggaggaa guggauuaag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  6258
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (wt)

<400>  6258
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gggaccugga uuuuguuugc uugccuccug ggagcagccu      120

ucucuaugcc ucuaccaccu cauccugggc acccugguua uaucaacuuc agcuaugagg      180

ugcuuacccc ucugaagugg uaccagaaca ugauaagaca uccgacuccc cagagucaug      240

cccuucagcc ucaucaccac auccccaugg ugccagcuca acagcccggg aucccccagc      300

agccaaugau gccacuuccu ggccaacacu ccaugacucc aacccaacac caccagccaa      360

accucccucu gcccgcccag cagcccuucc agccccagcc cguccagccc cagccucacc      420

agccccugca gccccaguca cccaugcacc ccauccagcc cuugcugcca cagccaccuc      480

ugccuccgau guucuccaug cagucucugc uuccugaccu gccucuggaa gcuuggccag      540

caacagacaa gaccaagcgg gaggaagugg auuaaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  6259
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (wt)

<400>  6259
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccac cucauccugg gcacccuggu uauaucaacu      120

ucagcuauga ggugcuuacc ccucugaagu gguaccagaa caugauaaga cauccguaca      180

cuuccuaugg guacgaaccc auggguggau ggcugcacca ccaaaucaua cccguggugu      240

cgcagcagac uccccagagu caugcccuuc agccucauca ccacaucccc auggugccag      300

cucaacagcc cgggaucccc cagcagccaa ugaugccacu uccuggccaa cacuccauga      360

cuccaaccca acaccaccag ccaaaccucc cucugcccgc ccagcagccc uuccagcccc      420

agcccgucca gccccagccu caccagcccc ugcagcccca gucacccaug caccccaucc      480

agcccuugcu gccacagcca ccucugccuc cgauguucuc caugcagucu cugcuuccug      540

accugccucu ggaagcuugg ccagcaacag acaagaccaa gcgggaggaa guggauuaag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  6260
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (wt)

<400>  6260
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg cccgccugcc gcugcugcuc gggcugcugc      120

ugcucccgcg ucccggccgg ccgcuggacu uggccgacua caccuaugac cuggcggagg      180

aggacgacuc ggagccccuc aacuacaaag accccugcaa ggcggcugcc uuucuugggg      240

acauugcccu ggacgaagag gaccugaggg ccuuccaggu acagcaggcu guggaucuca      300

gacggcacac agcucguaag uccuccauca aagcugcagu uccaggaaac acuucuaccc      360

ccagcugcca gagcaccaac gggcagccuc agaggggagc cugugggaga uggagaggua      420

gaucccguag ccggcgggcg gcgacguccc gaccagagcg uguguggccc gaugggguca      480

uccccuuugu cauuggggga aacuucacug guagccagag ggcagucuuc cggcaggcca      540

ugaggcacug ggagaagcac accuguguca ccuuccugga gcgcacugac gaggacagcu      600

auauuguguu caccuaucga ccuugcgggu gcugcuccua cgugggucgc cgcggcgggg      660

gcccccaggc caucuccauc ggcaagaacu gugacaaguu cggcauugug guccacgagc      720

ugggccacgu cgucggcuuc uggcacgaac acacucggcc agaccgggac cgccacguuu      780

ccaucguucg ugagaacauc cagccagggc aggaguauaa cuuccugaag auggagccuc      840

aggaggugga gucccugggg gagaccuaug acuucgacag caucaugcau uacgcucgga      900

acacauucuc caggggcauc uuccuggaua ccauuguccc caaguaugag gugaacgggg      960

ugaaaccucc cauuggccaa aggacacggc ucagcaaggg ggacauugcc caagcccgca     1020

agcuuuacaa gugcccagcc uguggagaga cccugcaaga cagcacaggc aacuucuccu     1080

ccccugaaua ccccaauggc uacucugcuc acaugcacug cguguggcgc aucucuguca     1140

cacccgggga gaagaucauc cugaacuuca cgucccugga ccuguaccgc agccgccugu     1200

gcugguacga cuauguggag guccgagaug gcuucuggag gaaggcgccc cuccgaggcc     1260

gcuucugcgg guccaaacuc ccugagccua ucgucuccac ugacagccgc cucuggguug     1320

aauuccgcag cagcagcaau uggguuggaa agggcuucuu ugcagucuac gaagccaucu     1380

gcggggguga ugugaaaaag gacuauggcc acauucaauc gcccaacuac ccagacgauu     1440

accggcccag caaagucugc aucuggcgga uccagguguc ugagggcuuc cacgugggcc     1500

ucacauucca guccuuugag auugagcgcc acgacagcug ugccuacgac uaucuggagg     1560

ugcgcgacgg gcacagugag agcagcaccc ucaucgggcg cuacuguggc uaugagaagc     1620

cugaugacau caagagcacg uccagccgcc ucuggcucaa guucgucucu gacgggucca     1680

uuaacaaagc gggcuuugcc gucaacuuuu ucaaagaggu ggacgagugc ucucggccca     1740

accgcggggg cugugagcag cggugccuca acacccuggg cagcuacaag ugcagcugug     1800

accccgggua cgagcuggcc ccagacaagc gccgcuguga ggcugcuugu ggcggauucc     1860

ucaccaagcu caacggcucc aucaccagcc cgggcuggcc caaggaguac ccccccaaca     1920

agaacugcau cuggcagcug guggccccca cccaguaccg caucucccug caguuugacu     1980

ucuuugagac agagggcaau gaugugugca aguacgacuu cguggaggug cgcaguggac     2040

ucacagcuga cuccaagcug cauggcaagu ucugugguuc ugagaagccc gaggucauca     2100

ccucccagua caacaacaug cgcguggagu ucaaguccga caacaccgug uccaaaaagg     2160

gcuucaaggc ccacuucuuc ucagacaagg acgagugcuc caaggauaac ggcggcugcc     2220

agcaggacug cgucaacacg uucggcaguu augagugcca augccgcagu ggcuucgucc     2280

uccaugacaa caagcacgac ugcaaagaag ccggcuguga ccacaaggug acauccacca     2340

gugguaccau caccagcccc aacuggccug acaaguaucc cagcaagaag gagugcacgu     2400

gggccaucuc cagcaccccc gggcaccggg ucaagcugac cuucauggag auggacaucg     2460

agucccagcc ugagugugcc uacgaccacc uagagguguu cgacgggcga gacgccaagg     2520

cccccguccu cggccgcuuc ugugggagca agaagcccga gcccguccug gccacaggca     2580

gccgcauguu ccugcgcuuc uacucagaua acucggucca gcgaaagggc uuccaggccu     2640

cccacgccac agagugcggg ggccagguac gggcagacgu gaagaccaag gaccuuuacu     2700

cccacgccca guuuggcgac aacaacuacc cugggggugu ggacugugag ugggucauug     2760

uggccgagga aggcuacggc guggagcucg uguuccagac cuuugaggug gaggaggaga     2820

ccgacugcgg cuaugacuac auggagcucu ucgacggcua cgacagcaca gcccccaggc     2880

uggggcgcua cuguggcuca gggccuccug aggaggugua cucggcggga gauucugucc     2940

uggugaaguu ccacucggau gacaccauca ccaaaaaagg uuuccaccug cgauacacca     3000

gcaccaaguu ccaggacaca cuccacagca ggaagugagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  6261
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (wt)

<400>  6261
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggga cccgcugucu ucuagcguug cugcuucccc      120

agguccuccu gggcggcgcg gcuggccucg uuccggagcu gggccgcagg aaguucgcgg      180

cggcgucguc gggccgcccc ucaucccagc ccucugacga gguccugagc gaguucgagu      240

ugcggcugcu cagcauguuc ggccugaaac agagacccac ccccagcagg gacgccgugg      300

ugccccccua caugcuagac cuguaucgca ggcacucagg ucagccgggc ucacccgccc      360

cagaccaccg guuggagagg gcagccagcc gagccaacac ugugcgcagc uuccaccaug      420

aagaaucuuu ggaagaacua ccagaaacga gugggaaaac aacccggaga uucuucuuua      480

auuuaaguuc uauccccacg gaggaguuua ucaccucagc agagcuucag guuuuccgag      540

aacagaugca agaugcuuua ggaaacaaua gcaguuucca ucaccgaauu aauauuuaug      600

aaaucauaaa accugcaaca gccaacucga aauuccccgu gaccagacuu uuggacacca      660

gguuggugaa ucagaaugca agcagguggg aaaguuuuga ugucaccccc gcugugaugc      720

gguggacugc acagggacac gccaaccaug gauucguggu ggaaguggcc cacuuggagg      780

agaaacaagg ugucuccaag agacauguua ggauaagcag gucuuugcac caagaugaac      840

acagcugguc acagauaagg ccauugcuag uaacuuuugg ccaugaugga aaagggcauc      900

cucuccacaa aagagaaaaa cgucaagcca aacacaaaca gcggaaacgc cuuaagucca      960

gcuguaagag acacccuuug uacguggacu ucagugacgu gggguggaau gacuggauug     1020

uggcuccccc gggguaucac gccuuuuacu gccacggaga augcccuuuu ccucuggcug     1080

aucaucugaa cuccacuaau caugccauug uucagacguu ggucaacucu guuaacucua     1140

agauuccuaa ggcaugcugu gucccgacag aacucagugc uaucucgaug cuguaccuug     1200

acgagaauga aaagguugua uuaaagaacu aucaggacau gguuguggag gguugugggu     1260

gucgcuaggg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  6262
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (wt)

<400>  6262
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auuccuggua accgaaugcu gauggucguu uuauuaugcc      120

aaguccugcu aggaggcgcg agccaugcua guuugauacc ugagacgggg aagaaaaaag      180

ucgccgagau ucagggccac gcgggaggac gccgcucagg gcagagccau gagcuccugc      240

gggacuucga ggcgacacuu cugcagaugu uugggcugcg ccgccgcccg cagccuagca      300

agagugccgu cauuccggac uacaugcggg aucuuuaccg gcuucagucu ggggaggagg      360

aggaagagca gauccacagc acuggucuug aguauccuga gcgcccggcc agccgggcca      420

acaccgugag gagcuuccac cacgaagaac aucuggagaa caucccaggg accagugaaa      480

acucugcuuu ucguuuccuc uuuaaccuca gcagcauccc ugagaacgag gugaucuccu      540

cugcagagcu ucggcucuuc cgggagcagg uggaccaggg cccugauugg gaaaggggcu      600

uccaccguau aaacauuuau gagguuauga agcccccagc agaaguggug ccugggcacc      660

ucaucacacg acuacuggac acgagacugg uccaccacaa ugugacacgg ugggaaacuu      720

uugaugugag cccugcgguc cuucgcugga cccgggagaa gcagccaaac uaugggcuag      780

ccauugaggu gacucaccuc caucagacuc ggacccacca gggccagcau gucaggauua      840

gccgaucguu accucaaggg agugggaauu gggcccagcu ccggccccuc cuggucaccu      900

uuggccauga uggccggggc caugccuuga cccgacgccg gagggccaag cguagcccua      960

agcaucacuc acagcgggcc aggaagaaga auaagaacug ccggcgccac ucgcucuaug     1020

uggacuucag cgaugugggc uggaaugacu ggauuguggc cccaccaggc uaccaggccu     1080

ucuacugcca uggggacugc cccuuuccac uggcugacca ccucaacuca accaaccaug     1140

ccauugugca gacccugguc aauucuguca auuccaguau ccccaaagcc uguugugugc     1200

ccacugaacu gagugccauc uccaugcugu accuggauga guaugauaag gugguacuga     1260

aaaauuauca ggagauggua guagagggau gugggugccg cugaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  6263
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (wt)

<400>  6263
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggggcugg ggcggagggc gcaguggcug ugcugguggu      120

gggggcugcu gugcagcugc ugcgggcccc cgccgcugcg gccgcccuug cccgcugccg      180

cggccgccgc cgccgggggg cagcugcugg gggacggcgg gagccccggc cgcacggagc      240

agccgccgcc gucgccgcag uccuccucgg gcuuccugua ccggcggcuc aagacgcagg      300

agaagcggga gaugcagaag gagaucuugu cggugcuggg gcucccgcac cggccccggc      360

cccugcacgg ccuccaacag ccgcagcccc cggcgcuccg gcagcaggag gagcagcagc      420

agcagcagca gcugccucgc ggagagcccc cucccgggcg acugaagucc gcgccccucu      480

ucaugcugga ucuguacaac gcccuguccg ccgacaacga cgaggacggg gcgucggagg      540

gggagaggca gcaguccugg ccccacgaag cagccagcuc gucccagcgu cggcagccgc      600

ccccgggcgc cgcgcacccg cucaaccgca agagccuucu ggcccccgga ucuggcagcg      660

gcggcgcguc cccacugacc agcgcgcagg acagcgccuu ccucaacgac gcggacaugg      720

ucaugagcuu ugugaaccug guggaguacg acaaggaguu cuccccucgu cagcgacacc      780

acaaagaguu caaguucaac uuaucccaga uuccugaggg ugagguggug acggcugcag      840

aauuccgcau cuacaaggac uguguuaugg ggaguuuuaa aaaccaaacu uuucuuauca      900

gcauuuauca agucuuacag gagcaucagc acagagacuc ugaccuguuu uuguuggaca      960

cccguguagu augggccuca gaagaaggcu ggcuggaauu ugacaucacg gccacuagca     1020

aucugugggu ugugacucca cagcauaaca uggggcuuca gcugagcgug gugacaaggg     1080

auggagucca cguccacccc cgagccgcag gccugguggg cagagacggc ccuuacgaca     1140

agcagcccuu caugguggcu uucuucaaag ugagugaggu gcacgugcgc accaccaggu     1200

cagccuccag ccggcgccga caacagaguc guaaucgcuc uacccagucc caggacgugg     1260

cgcgggucuc cagugcuuca gauuacaaca gcagugaauu gaaaacagcc ugcaggaagc     1320

augagcugua ugugaguuuc caagaccugg gauggcagga cuggaucauu gcacccaagg     1380

gcuaugcugc caauuacugu gauggagaau gcuccuuccc acucaacgca cacaugaaug     1440

caaccaacca cgcgauugug cagaccuugg uucaccuuau gaaccccgag uaugucccca     1500

aaccgugcug ugcgccaacu aagcuaaaug ccaucucggu ucuuuacuuu gaugacaacu     1560

ccaaugucau ucugaaaaaa uacaggaaua ugguuguaag agcuugugga ugccacuaag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  6264
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (wt)

<400>  6264
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugcgcu cacugcgagc ugcggcgccg cacagcuucg      120

uggcgcucug ggcaccccug uuccugcugc gcuccgcccu ggccgacuuc agccuggaca      180

acgaggugca cucgagcuuc auccaccggc gccuccgcag ccaggagcgg cgggagaugc      240

agcgcgagau ccucuccauu uugggcuugc cccaccgccc gcgcccgcac cuccagggca      300

agcacaacuc ggcacccaug uucaugcugg accuguacaa cgccauggcg guggaggagg      360

gcggcgggcc cggcggccag ggcuucuccu accccuacaa ggccgucuuc aguacccagg      420

gccccccucu ggccagccug caagauagcc auuuccucac cgacgccgac auggucauga      480

gcuucgucaa ccucguggaa caugacaagg aauucuucca cccacgcuac caccaucgag      540

aguuccgguu ugaucuuucc aagaucccag aaggggaagc ugucacggca gccgaauucc      600

ggaucuacaa ggacuacauc cgggaacgcu ucgacaauga gacguuccgg aucagcguuu      660

aucaggugcu ccaggagcac uugggcaggg aaucggaucu cuuccugcuc gacagccgua      720

cccucugggc cucggaggag ggcuggcugg uguuugacau cacagccacc agcaaccacu      780

ggguggucaa uccgcggcac aaccugggcc ugcagcucuc gguggagacg cuggaugggc      840

agagcaucaa ccccaaguug gcgggccuga uugggcggca cgggccccag aacaagcagc      900

ccuucauggu ggcuuucuuc aaggccacgg agguccacuu ccgcagcauc cgguccacgg      960

ggagcaaaca gcgcagccag aaccgcucca agacgcccaa gaaccaggaa gcccugcgga     1020

uggccaacgu ggcagagaac agcagcagcg accagaggca ggccuguaag aagcacgagc     1080

uguaugucag cuuccgagac cugggcuggc aggacuggau caucgcgccu gaaggcuacg     1140

ccgccuacua cugugagggg gagugugccu ucccucugaa cuccuacaug aacgccacca     1200

accacgccau cgugcagacg cugguccacu ucaucaaccc ggaaacggug cccaagcccu     1260

gcugugcgcc cacgcagcuc aaugccaucu ccguccucua cuucgaugac agcuccaacg     1320

ucauccugaa gaaauacaga aacauggugg uccgggccug uggcugccac uagggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  6265
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (wt)

<400>  6265
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagccucug cagcacuucu gugucugcug cucacagcag      120

cugcuuucag cccccagggg cuugcucagc caguugggau uaauacuuca acuaccugcu      180

gcuacagauu uaucaauaag aaaaucccua agcagaggcu ggagagcuac agaaggacca      240

ccaguagcca cuguccccgg gaagcuguaa ucuucaagac caaacuggac aaggagaucu      300

gugcugaccc cacacagaag uggguccagg acuuuaugaa gcaccuggac aagaaaaccc      360

aaacuccaaa gcuuugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  6266
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (wt)

<400>  6266
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucacuc uuaucauucu guugccagua guuucaaaau      120

uuaguuuugu uagucucuca gcaccgcagc acuggagcug uccugaaggu acucucgcag      180

gaaaugggaa uucuacuugu guggguccug cacccuucuu aauuuucucc cauggaaaua      240

guaucuuuag gauugacaca gaaggaacca auuaugagca auugguggug gaugcuggug      300

ucucagugau cauggauuuu cauuauaaug agaaaagaau cuauugggug gauuuagaaa      360

gacaacuuuu gcaaagaguu uuucugaaug ggucaaggca agagagagua uguaauauag      420

agaaaaaugu uucuggaaug gcaauaaauu ggauaaauga agaaguuauu uggucaaauc      480

aacaggaagg aaucauuaca guaacagaua ugaaaggaaa uaauucccac auucuuuuaa      540

gugcuuuaaa auauccugca aauguagcag uugauccagu agaaagguuu auauuuuggu      600

cuucagaggu ggcuggaagc cuuuauagag cagaucucga ugguguggga gugaaggcuc      660

uguuggagac aucagagaaa auaacagcug ugucauugga ugugcuugau aagcggcugu      720

uuuggauuca guacaacaga gaaggaagca auucucuuau uugcuccugu gauuaugaug      780

gagguucugu ccacauuagu aaacauccaa cacagcauaa uuuguuugca augucccuuu      840

uuggugaccg uaucuucuau ucaacaugga aaaugaagac aauuuggaua gccaacaaac      900

acacuggaaa ggacaugguu agaauuaacc uccauucauc auuuguacca cuuggugaac      960

ugaaaguagu gcauccacuu gcacaaccca aggcagaaga ugacacuugg gagccugagc     1020

agaaacuuug caaauugagg aaaggaaacu gcagcagcac uguguguggg caagaccucc     1080

agucacacuu gugcaugugu gcagagggau acgcccuaag ucgagaccgg aaguacugug     1140

aagauguuaa ugaaugugcu uuuuggaauc auggcuguac ucuugggugu aaaaacaccc     1200

cuggauccua uuacugcacg ugcccuguag gauuuguucu gcuuccugau gggaaacgau     1260

gucaucaacu uguuuccugu ccacgcaaug ugucugaaug cagccaugac uguguucuga     1320

caucagaagg ucccuuaugu uucuguccug aaggcucagu gcuugagaga gaugggaaaa     1380

cauguagcgg uuguuccuca cccgauaaug guggauguag ccagcucugc guuccucuua     1440

gcccaguauc cugggaaugu gauugcuuuc cuggguauga ccuacaacug gaugaaaaaa     1500

gcugugcagc uucaggacca caaccauuuu ugcuguuugc caauucucaa gauauucgac     1560

acaugcauuu ugauggaaca gacuauggaa cucugcucag ccagcagaug ggaaugguuu     1620

augcccuaga ucaugacccu guggaaaaua agauauacuu ugcccauaca gcccugaagu     1680

ggauagagag agcuaauaug gaugguuccc agcgagaaag gcuuauugag gaaggaguag     1740

augugccaga aggucuugcu guggacugga uuggccguag auucuauugg acagacagag     1800

ggaaaucucu gauuggaagg agugauuuaa augggaaacg uuccaaaaua aucacuaagg     1860

agaacaucuc ucaaccacga ggaauugcug uucauccaau ggccaagaga uuauucugga     1920

cugauacagg gauuaaucca cgaauugaaa guucuucccu ccaaggccuu ggccgucugg     1980

uuauagccag cucugaucua aucuggccca guggaauaac gauugacuuc uuaacugaca     2040

aguuguacug gugcgaugcc aagcagucug ugauugaaau ggccaaucug gaugguucaa     2100

aacgccgaag acuuacccag aaugauguag gucacccauu ugcuguagca guguuugagg     2160

auuaugugug guucucagau ugggcuaugc caucaguaau gagaguaaac aagaggacug     2220

gcaaagauag aguacgucuc caaggcagca ugcugaagcc cucaucacug guugugguuc     2280

auccauuggc aaaaccagga gcagaucccu gcuuauauca aaacggaggc ugugaacaua     2340

uuugcaaaaa gaggcuugga acugcuuggu guucgugucg ugaagguuuu augaaagccu     2400

cagaugggaa aacgugucug gcucuggaug gucaucagcu guuggcaggu ggugaaguug     2460

aucuaaagaa ccaaguaaca ccauuggaca ucuuguccaa gacuagagug ucagaagaua     2520

acauuacaga aucucaacac augcuagugg cugaaaucau ggugucagau caagaugacu     2580

gugcuccugu gggaugcagc auguaugcuc gguguauuuc agagggagag gaugccacau     2640

gucaguguuu gaaaggauuu gcuggggaug gaaaacuaug uucugauaua gaugaaugug     2700

agaugggugu cccagugugc cccccugccu ccuccaagug caucaacacc gaaggugguu     2760

augucugccg gugcucagaa ggcuaccaag gagaugggau ucacugucuu gauauugaug     2820

agugccaacu gggggagcac agcuguggag agaaugccag cugcacaaau acagagggag     2880

gcuauaccug caugugugcu ggacgccugu cugaaccagg acugauuugc ccugacucua     2940

cuccaccccc ucaccucagg gaagaugacc accacuauuc cguaagaaau agugacucug     3000

aauguccccu gucccacgau ggguacugcc uccaugaugg ugugugcaug uauauugaag     3060

cauuggacaa guaugcaugc aacuguguug uuggcuacau cggggagcga ugucaguacc     3120

gagaccugaa guggugggaa cugcgccacg cuggccacgg gcagcagcag aaggucaucg     3180

ugguggcugu cugcguggug gugcuuguca ugcugcuccu ccugagccug uggggggccc     3240

acuacuacag gacucagaag cugcuaucga aaaacccaaa gaauccuuau gaggagucga     3300

gcagagaugu gaggagucgc aggccugcug acacugagga ugggaugucc ucuugcccuc     3360

aaccuugguu ugugguuaua aaagaacacc aagaccucaa gaaugggggu caaccagugg     3420

cuggugagga uggccaggca gcagaugggu caaugcaacc aacuucaugg aggcaggagc     3480

cccaguuaug uggaaugggc acagagcaag gcugcuggau uccaguaucc agugauaagg     3540

gcuccugucc ccagguaaug gagcgaagcu uucauaugcc cuccuauggg acacagaccc     3600

uugaaggggg ugucgagaag ccccauucuc uccuaucagc uaacccauua uggcaacaaa     3660

gggcccugga cccaccacac caaauggagc ugacucagug aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  6267
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (wt)

<400>  6267
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgcgggga ggaggaugga gaugcucugu gccggcaggg      120

ucccugcgcu gcugcucugc cuggguuucc aucuucuaca ggcaguccuc aguacaacug      180

ugauuccauc auguauccca ggagagucca gugauaacug cacagcuuua guucagacag      240

aagacaaucc acguguggcu caagugucaa uaacaaagug uagcucugac augaauggcu      300

auuguuugca uggacagugc aucuaucugg uggacaugag ucaaaacuac ugcaggugug      360

aaguggguua uacugguguc cgaugugaac acuucuuuuu aaccguccac caaccuuuaa      420

gcaaagaaua uguggcuuug accgugauuc uuauuauuuu guuucuuauc acagucgucg      480

guuccacaua uuauuucugc agaugguaca gaaaucgaaa aaguaaagaa ccaaagaagg      540

aauaugagag aguuaccuca ggggauccag aguugccgca agucugagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  6268
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (wt)

<400>  6268
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcugaagggg aaaucaccac cuucacagcc cugaccgaga      120

aguuuaaucu gccuccaggg aauuacaaga agcccaaacu ccucuacugu agcaacgggg      180

gccacuuccu gaggauccuu ccggauggca caguggaugg gacaagggac aggagcgacc      240

agcacauuca gcugcagcuc agugcggaaa gcguggggga gguguauaua aagaguaccg      300

agacuggcca guacuuggcc auggacaccg acgggcuuuu auacggcuca cagacaccaa      360

augaggaaug uuuguuccug gaaaggcugg aggagaacca uuacaacacc uauauaucca      420

agaagcaugc agagaagaau ugguuuguug gccucaagaa gaaugggagc ugcaaacgcg      480

guccucggac ucacuauggc cagaaagcaa ucuuguuucu cccccugcca gucucuucug      540

auuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  6269
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (wt)

<400>  6269
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggugugg gggguggaga uguagaagau gugacgccgc      120

ggcccggcgg gugccagauu agcggacgcg gugcccgcgg uugcaacggg aucccgggcg      180

cugcagcuug ggaggcggcu cuccccaggc ggcguccgcg gagacaccca uccgugaacc      240

ccaggucccg ggccgccggc ucgccgcgca ccaggggccg gcggacagaa gagcggccga      300

gcggcucgag gcugggggac cgcgggcgcg gccgcgcgcu gccgggcggg aggcuggggg      360

gccggggccg gggccgugcc ccggagcggg ucggaggccg gggccggggc cgggggacgg      420

cggcuccccg cgcggcucca gcggcucggg gaucccggcc gggccccgca gggaccaugg      480

cagccgggag caucaccacg cugcccgccu ugcccgagga uggcggcagc ggcgccuucc      540

cgcccggcca cuucaaggac cccaagcggc uguacugcaa aaacgggggc uucuuccugc      600

gcauccaccc cgacggccga guugacgggg uccgggagaa gagcgacccu cacaucaagc      660

uacaacuuca agcagaagag agaggaguug ugucuaucaa aggagugugu gcuaaccguu      720

accuggcuau gaaggaagau ggaagauuac uggcuucuaa auguguuacg gaugaguguu      780

ucuuuuuuga acgauuggaa ucuaauaacu acaauacuua ccggucaagg aaauacacca      840

guugguaugu ggcacugaaa cgaacugggc aguauaaacu uggauccaaa acaggaccug      900

ggcagaaagc uauacuuuuu cuuccaaugu cugcuaagag cugaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  6270
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (wt)

<400>  6270
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uacugacaug gauccugcca acuuugcucu      120

acagaucaug cuuucacauu aucugucuag uggguacuau aucuuuagcu ugcaaugaca      180

ugacuccaga gcaaauggcu acaaauguga acuguuccag cccugagcga cacacaagaa      240

guuaugauua cauggaagga ggggauauaa gagugagaag acucuucugu cgaacacagu      300

gguaccugag gaucgauaaa agaggcaaag uaaaagggac ccaagagaug aagaauaauu      360

acaauaucau ggaaaucagg acaguggcag uuggaauugu ggcaaucaaa gggguggaaa      420

gugaauucua ucuugcaaug aacaaggaag gaaaacucua ugcaaagaaa gaaugcaaug      480

aagauuguaa cuucaaagaa cuaauucugg aaaaccauua caacacauau gcaucagcua      540

aauggacaca caacggaggg gaaauguuug uugccuuaaa ucaaaagggg auuccuguaa      600

gaggaaaaaa aacgaagaaa gaacaaaaaa cagcccacuu ucuuccuaug gcaauaacuu      660

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  6271
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (wt)

<400>  6271
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugcugc cgucgguggu gcugaagcuc uuucuggcug      120

caguucucuc ggcacuggug acuggcgaga gccuggagcg gcuucggaga gggcuagcug      180

cuggaaccag caacccggac ccucccacug uauccacgga ccagcugcua ccccuaggag      240

gcggccggga ccggaaaguc cgugacuugc aagaggcaga ucuggaccuu uugagaguca      300

cuuuauccuc caagccacaa gcacuggcca caccaaacaa ggaggagcac gggaaaagaa      360

agaagaaagg caaggggcua gggaagaaga gggacccaug ucuucggaaa uacaaggacu      420

ucugcaucca uggagaaugc aaauauguga aggagcuccg ggcucccucc ugcaucugcc      480

acccggguua ccauggagag aggugucaug ggcugagccu cccaguggaa aaucgcuuau      540

auaccuauga ccacacaacc auccuggccg ugguggcugu ggugcuguca ucugucuguc      600

ugcuggucau cguggggcuu cucauguuua gguaccauag gagaggaggu uaugaugugg      660

aaaaugaaga gaaagugaag uugggcauga cuaauuccca cugaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  6272
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (wt)

<400>  6272
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca aacuccugcc agcccugcug cugcagcaug      120

uccuccugca ucuccuccug cuccccaucg ccauccccua ugcagaggga caaaggaaaa      180

gaagaaauac aauucaugaa uucaaaaaau cagcaaagac uacccuaauc aaaauagauc      240

cagcacugaa gauaaaaacc aaaaaaguga auacugcaga ccaaugugcu aauagaugua      300

cuaggaauaa aggacuucca uucacuugca aggcuuuugu uuuugauaaa gcaagaaaac      360

aaugccucug guuccccuuc aauagcaugu caaguggagu gaaaaaagaa uuuggccaug      420

aauuugaccu cuaugaaaac aaagacuaca uuagaaacug caucauuggu aaaggacgca      480

gcuacaaggg aacaguaucu aucacuaaga guggcaucaa augucagccc uggaguucca      540

ugauaccaca cgaacacagc uuuuugccuu cgagcuaucg ggguaaagac cuacaggaaa      600

acuacugucg aaauccucga ggggaagaag ggggacccug guguuucaca agcaauccag      660

agguacgcua cgaagucugu gacauuccuc aguguucaga aguugaaugc augaccugca      720

auggggagag uuaucgaggu cucauggauc auacagaauc aggcaagauu ugucagcgcu      780

gggaucauca gacaccacac cggcacaaau ucuugccuga aagauauccc gacaagggcu      840

uugaugauaa uuauugccgc aaucccgaug gccagccgag gccauggugc uauacucuug      900

acccucacac ccgcugggag uacugugcaa uuaaaacaug cgcugacaau acuaugaaug      960

acacugaugu uccuuuggaa acaacugaau gcauccaagg ucaaggagaa ggcuacaggg     1020

gcacugucaa uaccauuugg aauggaauuc caugucagcg uugggauucu caguauccuc     1080

acgagcauga caugacuccu gaaaauuuca agugcaagga ccuacgagaa aauuacugcc     1140

gaaauccaga ugggucugaa ucacccuggu guuuuaccac ugauccaaac auccgaguug     1200

gcuacugcuc ccaaauucca aacugugaua ugucacaugg acaagauugu uaucguggga     1260

auggcaaaaa uuauaugggc aacuuauccc aaacaagauc uggacuaaca uguucaaugu     1320

gggacaagaa cauggaagac uuacaucguc auaucuucug ggaaccagau gcaaguaagc     1380

ugaaugagaa uuacugccga aauccagaug augaugcuca uggacccugg ugcuacacgg     1440

gaaauccacu cauuccuugg gauuauugcc cuauuucucg uugugaaggu gauaccacac     1500

cuacaauagu caauuuagac caucccguaa uaucuugugc caaaacgaaa caauugcgag     1560

uuguaaaugg gauuccaaca cgaacaaaca uaggauggau gguuaguuug agauacagaa     1620

auaaacauau cugcggagga ucauugauaa aggagaguug gguucuuacu gcacgacagu     1680

guuucccuuc ucgagacuug aaagauuaug aagcuuggcu uggaauucau gauguccacg     1740

gaagaggaga ugagaaaugc aaacagguuc ucaauguuuc ccagcuggua uauggcccug     1800

aaggaucaga ucugguuuua augaagcuug ccaggccugc uguccuggau gauuuuguua     1860

guacgauuga uuuaccuaau uauggaugca caauuccuga aaagaccagu ugcaguguuu     1920

auggcugggg cuacacugga uugaucaacu augauggccu auuacgagug gcacaucucu     1980

auauaauggg aaaugagaaa ugcagccagc aucaucgagg gaaggugacu cugaaugagu     2040

cugaaauaug ugcuggggcu gaaaagauug gaucaggacc augugagggg gauuauggug     2100

gcccacuugu uugugagcaa cauaaaauga gaaugguucu uggugucauu guuccugguc     2160

guggaugugc cauuccaaau cguccuggua uuuuuguccg aguagcauau uaugcaaaau     2220

ggauacacaa aauuauuuua acauauaagg uaccacaguc auagggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  6273
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (wt)

<400>  6273
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaagccg cggcgaucgg caucgaccug ggcaccaccu      120

acuccugcgu ggggguguuc caacacggca agguggagau caucgccaac gaccagggca      180

accgcaccac ccccagcuac guggccuuca cggacaccga gcggcucauc ggggaugcgg      240

ccaagaacca gguggcgcug aacccgcaga acaccguguu ugacgcgaag cggcugauug      300

gccgcaaguu cggcgacccg guggugcagu cggacaugaa gcacuggccu uuccagguga      360

ucaacgacgg agacaagccc aaggugcagg ugagcuacaa gggggagacc aaggcauucu      420

accccgagga gaucucgucc auggugcuga ccaagaugaa ggagaucgcc gaggcguacc      480

ugggcuaccc ggugaccaac gcggugauca ccgugccggc cuacuucaac gacucgcagc      540

gccaggccac caaggaugcg ggugugaucg cggggcucaa cgugcugcgg aucaucaacg      600

agcccacggc cgccgccauc gccuacggcc uggacagaac gggcaagggg gagcgcaacg      660

ugcucaucuu ugaccugggc gggggcaccu ucgacguguc cauccugacg aucgacgacg      720

gcaucuucga ggugaaggcc acggccgggg acacccaccu ggguggggag gacuuugaca      780

acaggcuggu gaaccacuuc guggaggagu ucaagagaaa acacaagaag gacaucagcc      840

agaacaagcg agccgugagg cggcugcgca ccgccugcga gagggccaag aggacccugu      900

cguccagcac ccaggccagc cuggagaucg acucccuguu ugagggcauc gacuucuaca      960

cguccaucac cagggcgagg uucgaggagc ugugcuccga ccuguuccga agcacccugg     1020

agcccgugga gaaggcucug cgcgacgcca agcuggacaa ggcccagauu cacgaccugg     1080

uccuggucgg gggcuccacc cgcaucccca aggugcagaa gcugcugcag gacuucuuca     1140

acgggcgcga ccugaacaag agcaucaacc ccgacgaggc uguggccuac ggggcggcgg     1200

ugcaggcggc cauccugaug ggggacaagu ccgagaacgu gcaggaccug cugcugcugg     1260

acguggcucc ccugucgcug gggcuggaga cggccggagg cgugaugacu gcccugauca     1320

agcgcaacuc caccaucccc accaagcaga cgcagaucuu caccaccuac uccgacaacc     1380

aacccggggu gcugauccag guguacgagg gcgagagggc caugacgaaa gacaacaauc     1440

uguuggggcg cuucgagcug agcggcaucc cuccggcccc caggggcgug ccccagaucg     1500

aggugaccuu cgacaucgau gccaacggca uccugaacgu cacggccacg gacaagagca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg ccgccugagc aaggaggaga     1620

ucgagcgcau ggugcaggag gcggagaagu acaaagcgga ggacgaggug cagcgcgaga     1680

gggugucagc caagaacgcc cuggaguccu acgccuucaa caugaagagc gccguggagg     1740

augaggggcu caagggcaag aucagcgagg cggacaagaa gaaggugcug gacaaguguc     1800

aagaggucau cucguggcug gacgccaaca ccuuggccga gaaggacgag uuugagcaca     1860

agaggaagga gcuggagcag guguguaacc ccaucaucag cggacuguac cagggugccg     1920

guggucccgg gccugggggc uucggggcuc agggucccaa gggagggucu gggucaggcc     1980

ccaccauuga ggagguagau uagggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6274
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (wt)

<400>  6274
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaagccg cggcgaucgg caucgaccug ggcaccaccu      120

acuccugcgu ggggguguuc caacacggca agguggagau caucgccaac gaccagggca      180

accgcaccac ccccagcuac guggccuuca cggacaccga gcggcucauc ggggaugcgg      240

ccaagaacca gguggcgcug aacccgcaga acaccguguu ugacgcgaag cggcugauug      300

gccgcaaguu cggcgacccg guggugcagu cggacaugaa gcacuggccu uuccagguga      360

ucaacgacgg agacaagccc aaggugcagg ugagcuacaa gggggagacc aaggcauucu      420

accccgagga gaucucgucc auggugcuga ccaagaugaa ggagaucgcc gaggcguacc      480

ugggcuaccc ggugaccaac gcggugauca ccgugccggc cuacuucaac gacucgcagc      540

gccaggccac caaggaugcg ggugugaucg cggggcucaa cgugcugcgg aucaucaacg      600

agcccacggc cgccgccauc gccuacggcc uggacagaac gggcaagggg gagcgcaacg      660

ugcucaucuu ugaccugggc gggggcaccu ucgacguguc cauccugacg aucgacgacg      720

gcaucuucga ggugaaggcc acggccgggg acacccaccu ggguggggag gacuuugaca      780

acaggcuggu gaaccacuuc guggaggagu ucaagagaaa acacaagaag gacaucagcc      840

agaacaagcg agccgugagg cggcugcgca ccgccugcga gagggccaag aggacccugu      900

cguccagcac ccaggccagc cuggagaucg acucccuguu ugagggcauc gacuucuaca      960

cguccaucac cagggcgagg uucgaggagc ugugcuccga ccuguuccga agcacccugg     1020

agcccgugga gaaggcucug cgcgacgcca agcuggacaa ggcccagauu cacgaccugg     1080

uccuggucgg gggcuccacc cgcaucccca aggugcagaa gcugcugcag gacuucuuca     1140

acgggcgcga ccugaacaag agcaucaacc ccgacgaggc uguggccuac ggggcggcgg     1200

ugcaggcggc cauccugaug ggggacaagu ccgagaacgu gcaggaccug cugcugcugg     1260

acguggcucc ccugucgcug gggcuggaga cggccggagg cgugaugacu gcccugauca     1320

agcgcaacuc caccaucccc accaagcaga cgcagaucuu caccaccuac uccgacaacc     1380

aacccggggu gcugauccag guguacgagg gcgagagggc caugacgaaa gacaacaauc     1440

uguuggggcg cuucgagcug agcggcaucc cuccggcccc caggggcgug ccccagaucg     1500

aggugaccuu cgacaucgau gccaacggca uccugaacgu cacggccacg gacaagagca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg ccgccugagc aaggaggaga     1620

ucgagcgcau ggugcaggag gcggagaagu acaaagcgga ggacgaggug cagcgcgaga     1680

gggugucagc caagaacgcc cuggaguccu acgccuucaa caugaagagc gccguggagg     1740

augaggggcu caagggcaag aucagcgagg cggacaagaa gaagguucug gacaaguguc     1800

aagaggucau cucguggcug gacgccaaca ccuuggccga gaaggacgag uuugagcaca     1860

agaggaagga gcuggagcag guguguaacc ccaucaucag cggacuguac cagggugccg     1920

guggucccgg gccuggcggc uucggggcuc agggucccaa gggagggucu gggucaggcc     1980

cuaccauuga ggagguggau uagggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6275
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (wt)

<400>  6275
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuacugcca agggaaucgc cauaggcauc gaccugggca      120

ccaccuacuc cugugugggg guguuccagc acggcaaggu ggagaucauc gccaacgacc      180

agggcaaccg caccaccccc agcuacgugg ccuucacaga caccgagcgg cucauugggg      240

augcggccaa gaaccaggua gcaaugaauc cccagaacac uguuuuugau gcuaaacguc      300

ugaucggcag gaaauuuaau gauccuguug uacaagcaga uaugaaacuu uggccuuuuc      360

aagugauuaa ugaaggaggc aagcccaaag uccuuguguc cuacaaaggg gagaauaaag      420

cuuucuaccc ugaggaaauc ucuucgaugg uauugacuaa guugaaggag acugcugagg      480

ccuuuuuggg ccacccuguc accaaugcag ugauuaccgu gccagccuau uucaaugacu      540

cucaacguca ggcuacuaag gaugcaggug ugauugcugg acuuaaugug cuaagaauca      600

ucaaugagcc cacggcugcu gccauugccu augguuuaga uaaaggaggu caaggagaac      660

gacauguccu gauuuuugau cuggguggag gcacauuuga ugugucaauu cugaccauag      720

augaugggau uuuugaggua aaggccacug cuggggacac ucaccugggu ggggaggacu      780

uugacaacag gcuugugagc cacuucgugg aggaguucaa gaggaaacac aaaaaggaca      840

ucagccagaa caagcgagcc gugaggcggc ugcgcaccgc cugcgagagg gccaagagga      900

cccugucguc cagcacccag gccaaccuag aaauugauuc acuuuaugaa ggcauugacu      960

ucuauacauc caucaccaga gcucgauuug aagaguugug ugcagaccug uuuaggggua     1020

cccuggagcc uguagaaaaa gcgcuucggg augccaagau ggauaaggcu aaaauccaug     1080

acauuguuuu aguagggggc uccacccgca uccccaaggu gcagcggcug cuucaggacu     1140

acuucaaugg acgugaucuc aacaagagca ucaacccuga ugaggccgua gcauaugggg     1200

cugcgguaca agcagccauc cugauggggg acaagucuga gaagguacag gaccugcugc     1260

ugcuggacgu ggcuccccug ucccuggggc uggagacggc ugggggcgug augacugccc     1320

ugauaaagcg caacuccacc auccccacca agcagacaca gauuuucacc accuacucug     1380

acaaccaacc cggggugcug auccaggugu augagggcga gagggccaug acaaaggaca     1440

acaaccugcu ggggcgguuu gaccugacug gaaucccucc agcacccagg ggaguuccuc     1500

agaucgaggu gacguuugac auugaugcca augguauucu caaugucaca gccacggaca     1560

agagcaccgg caaggugaac aagaucacca ucaccaauga caagggccgc cugagcaagg     1620

aggagauuga gcgcaugguu cuggaugcug agaaauauaa agcugaagau gagguccaga     1680

gggagaaaau ugcugcaaag aaugccuuag aauccuaugc uuuuaacaug aagaguguug     1740

ugagugauga agguuugaag ggcaagauua gugagucuga uaaaaauaaa auauuggaua     1800

aaugcaacga gcuccuuucg uggcuggagg ucaaucaacu ggcagagaaa gaugaguuug     1860

aucauaagag aaaggaauug gagcagaugu guaacccuau caucacaaaa cucuaccaag     1920

gaggaugcac ugggccugcc ugcggaacag gguaugugcc uggaaggccu gccacaggcc     1980

ccacaauuga agaaguagau uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6276
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (wt)

<400>  6276
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucugcccgug gcccggcuau cggcaucgac cugggcacca      120

ccuauucgug cgucgggguc uuccaacaug gcaaggugga gaucaucgcc aacgaccagg      180

gcaaucgcac cacccccagc uacguggccu ucacggacac cgagcgccuc aucggcgacg      240

ccgccaagaa ccagguggcc augaacccca ccaacaccau cuucgacgcc aagaggcuga      300

uuggacggaa auucgaggau gccacagugc agucggauau gaaacacugg ccguuccggg      360

uggugagcga gggaggcaag cccaaagugc aaguagagua caagggggag accaagaccu      420

ucuucccaga ggagauaucc uccauggucc ucacgaagau gaaggagauc gcggaagccu      480

accugggggg caaggugcac agcgcgguca uaacgguccc ggccuauuuc aacgacucgc      540

agcgccaggc caccaaggac gcaggcacca ucacggggcu caaugugcug cgcaucauca      600

acgagcccac ggcggcggcc aucgccuacg gccuggacaa gaagggcugc gcgggcggcg      660

agaagaacgu gcucaucuuu gaccugggcg guggcacuuu cgacgugucc auccugacca      720

ucgaggaugg caucuucgag gugaagucca cggccggcga cacccaccug ggcggugagg      780

acuucgacaa ccgcauggug agccaccugg cggaggaguu caagcgcaag cacaagaagg      840

acauugggcc caacaagcgc gccgugaggc ggcugcgcac cgcuugcgag cgcgccaagc      900

gcacccugag cucguccacg caggcgagca ucgagaucga cucgcucuac gagggcgugg      960

acuucuauac guccaucacg cgcgcccgcu ucgaggagcu caaugccgac cucuuucgcg     1020

ggacccugga gccgguggag aaggcgcugc gcgacgccaa gcuggacaag ggccagaucc     1080

aggagaucgu gcuggugggc ggcuccacuc guauccccaa gauccagaag cugcugcagg     1140

auuucuucaa cggcaaggag cugaacaaga gcaucaaccc cgacgaggcg guggccuaug     1200

gcgccgcggu gcaggcggcc auccucaucg gcgacaaauc agagaaugug caggaccugc     1260

ugcuacucga cgugaccccg uugucgcugg gcaucgagac agcuggcggu gucaugaccc     1320

cacucaucaa gaggaacacc acgaucccca ccaagcagac gcagaccuuc accaccuacu     1380

cggacaacca gagcagcgua cuggugcagg uauacgaggg cgaacgggcc augaccaagg     1440

acaauaaccu gcugggcaag uucgaccuga ccgggauucc cccugcgccu cgcggggucc     1500

cccaaaucga gguuaccuuc gacauugacg ccaauggcau ccuuaacguu accgccgccg     1560

acaagagcac cgguaaggaa aacaaaauca ccaucaccaa ugacaaaggu cgucugagca     1620

aggacgacau ugaccggaug gugcaggagg cggagcggua caaaucggaa gaugaggcga     1680

aucgcgaccg agucgcggcc aaaaacgccc uggaguccua uaccuacaac aucaagcaga     1740

cgguggaaga cgagaaacug aggggcaaga uuagcgagca ggacaaaaac aagauccucg     1800

acaaguguca ggaggugauc aacuggcucg accgaaacca gauggcagag aaagaugagu     1860

augaacacaa gcagaaagag cucgaaagag uuugcaaccc caucaucagc aaacuuuacc     1920

aagguggucc uggcggcggc agcggcggcg gcgguucagg agccuccggg ggacccacca     1980

ucgaagaagu ggacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  6277
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (wt)

<400>  6277
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucgguggugg gcauagaccu gggcuuccag agcugcuacg      120

ucgcuguggc ccgcgccggc ggcaucgaga cuaucgcuaa ugaguauagc gaccgcugca      180

cgccggcuug cauuucuuuu gguccuaaga aucguucaau uggagcagca gcuaaaagcc      240

agguaauuuc uaaugcaaag aacacagucc aaggauuuaa aagauuccau ggccgagcau      300

ucucugaucc auuuguggag gcagaaaaau cuaaccuugc auaugauauu gugcaguugc      360

cuacaggauu aacagguaua aaggugacau auauggagga agagcgaaau uuuaccacug      420

agcaagugac ugccaugcuu uuguccaaac ugaaggagac agccgaaagu guucuuaaga      480

agccuguagu ugacuguguu guuucgguuc cuuguuucua uacugaugca gaaagacgau      540

cagugaugga ugcaacacag auugcugguc uuaauugcuu gcgauuaaug aaugaaacca      600

cugcaguugc ucuugcauau ggaaucuaua agcaggaucu uccugccuua gaagagaaac      660

caagaaaugu aguuuuugua gacaugggcc acucugcuua ucaaguuucu guaugugcau      720

uuaauagagg aaaacugaaa guucuggcca cugcauuuga cacgacauug ggagguagaa      780

aauuugauga aguguuagua aaucacuucu gugaagaauu ugggaagaaa uacaagcuag      840

acauuaaguc caaaauccgu gcauuauuac gacucucuca ggagugugag aaacucaaga      900

aauugaugag ugcaaaugcu ucagaucucc cuuugagcau ugaauguuuu augaaugaug      960

uugauguauc uggaacuaug aauagaggca aauuucugga gaugugcaau gaucucuuag     1020

cuagagugga gccaccacuu cguaguguuu uggaacaaac caaguuaaag aaagaagaua     1080

uuuaugcagu ggagauaguu gguggugcua cacgaauccc ugcgguaaaa gagaagauca     1140

gcaaauuuuu cgguaaagaa cuuaguacaa cauuaaaugc ugaugaagcu gucacucgag     1200

gcugugcauu gcagugugcc aucuuaucgc cugcuuucaa agucagagaa uuuucuauca     1260

cugauguagu accauaucca auaucucuga gauggaauuc uccagcugaa gaagggucaa     1320

gugacuguga agucuuuucc aaaaaucaug cugcuccuuu cucuaaaguu cuuacauuuu     1380

auagaaagga accuuucacu cuugaggccu acuacagcuc uccucaggau uugcccuauc     1440

cagauccugc uauagcucag uuuucaguuc agaaagucac uccucagucu gauggcucca     1500

guucaaaagu gaaagucaaa guucgaguaa auguccaugg cauuuucagu guguccagug     1560

caucuuuagu ggagguucac aagucugagg aaaaugagga gccaauggaa acagaucaga     1620

augcaaagga ggaagagaag augcaagugg accaggagga accacauguu gaagagcaac     1680

agcagcagac accagcagaa aauaaggcag agucugaaga aauggagacc ucucaagcug     1740

gauccaagga uaaaaagaug gaccaaccac cccaagccaa gaaggcaaaa gugaagacca     1800

guacugugga ccugccaauc gagaaucagc uauuauggca gauagacaga gagaugcuca     1860

acuuguacau ugaaaaugag gguaagauga ucaugcagga uaaacuggag aaggagcgga     1920

augaugcuaa gaacgcagug gaggaauaug uguaugaaau gagagacaag cuuaguggug     1980

aauaugagaa guuugugagu gaagaugauc guaacaguuu uacuuugaaa cuggaagaua     2040

cugaaaauug guuguaugag gauggagaag accagccaaa gcaaguuuau guugauaagu     2100

uggcugaauu aaaaaaucua ggucaaccua uuaagauacg uuuccaggaa ucugaagaac     2160

gaccaaaauu auuugaagaa cuagggaaac agauccaaca guauaugaaa auaaucagcu     2220

cuuucaaaaa caaggaggac caguaugauc auuuggaugc ugcugacaug acaaagguag     2280

aaaaaagcac aaaugaagca auggagugga ugaauaacaa gcuaaaucug cagaacaagc     2340

agaguuugac cauggaucca guugucaagu caaaagagau ugaagcuaaa auuaaggagc     2400

ugacaaguac uuguagcccu auaauuucaa agcccaaacc caaaguggaa ccuccaaaag     2460

aggaacaaaa aaaugcagag cagaauggac caguggaugg acaaggagac aacccaggcc     2520

cccaggcugc ugagcagggu acagacacag cugugccuuc ggauucagac aagaagcuuc     2580

cugaaaugga cauugauuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  6278
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (wt)

<400>  6278
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucugugguug gcauugaccu cggcuuucuc aacugcuaca      120

uugcugucgc gagaaguggc ggcaucgaga ccaucgccaa ugaguacagc gacaggugua      180

ccccggccug uauaucauug ggaucaagaa cucgagccau uggaaaugca gcaaagagcc      240

agauagucac gaacguaaga aauacaauuc auggcuucaa aaagcuucau gggcgaucau      300

uugaugaucc cauugugcaa acugaaagga ucaggcuucc cuaugaacug cagaaaaugc      360

cuaauggaag ugcaggaguu aaggugcggu acuuagagga agagagaccu uuugcaauug      420

agcaaguuac uggaaugcug uuagccaagc uuaaagagac uucagaaaau gcuuugaaga      480

aaccaguggc ugacugugug auuucaauuc cuagcuuuuu uacugaugcc gagagaagau      540

cugugauggc ugcagcccag guugcaggcu uaaauuguuu aagguugaug aaugaaacua      600

cugcaguugc acuggcguau ggaauuuaua aacaggaucu ucccccauua gaugagaaac      660

caagaaaugu aguauuuauu gauaugggac auucugccua ucaggucuug guuugugcuu      720

uuaacaaagg aaaacuuaaa gucuuggcua cuaccuuuga uccauauuug gguggcagga      780

acuuugauga ggcuuuagua gacuacuucu gugaugaguu caagaccaaa uauaagauaa      840

augugaaaga aaacucucgg gccuuguugc guuuauauca ggaaugugaa aaacuaaaga      900

agcuaaugag ugcaaaugca ucagaucuuc cauugaacau ugaguguuuc augaaugacc      960

uugauguuuc uaguaaaaug aacagggcuc aauuugaaca acugugugcu ucccuuuugg     1020

ccaggguuga accaccuuua aaagcaguaa uggaacaagc uaacuuacaa cgugaagaca     1080

uuaguaguau agaaauugua ggaggagcaa cacgaauucc ugcagugaaa gaacaaauca     1140

cuaaauucuu ucuuaaagac auaaguacca cauuaaaugc ugaugaagcu guugcaagag     1200

gaugugcguu acagugugcg auucucucac cagcauuuaa agugcgugaa uuuuccauaa     1260

cagaccuugu ucccuauuca aucacauuaa gguggaagac cucuuuugaa gauggaagug     1320

gggaauguga aguuuucugu aagaaccauc cugccccauu cucaaaaguc auuacuuucc     1380

acaagaagga accauuugaa cuagaagcau uuuauacuaa uuuacaugaa gugccuuauc     1440

cugaugcaag aauugggagc uucacuauuc agaauguuuu uccacagucu gauggugaua     1500

guuccaaagu gaagguuaaa guucguguua acauccaugg aaucuucagu guggcuagcg     1560

caucaguaau ugagaagcaa aauuuggaag gcgaucacag ugaugcucca auggagacag     1620

aaacuucauu uaaaaaugaa aacaaagaua auauggauaa aaugcagguu gaucaagaag     1680

aagggcauca aaaaugucau gcugaacaca cuccagaaga ggaaauugau cauacaggag     1740

ccaaaacaaa gucagcuguc ucagacaaac aagaccgauu aaaucagaca cuuaaaaaag     1800

gaaaagucaa aaguauugau cuaccgaucc agaguagccu auguagacaa cuaggccaag     1860

aucuucucaa cagcuacauu gaaaaugagg ggaagaugau caugcaagau aaguuagaga     1920

aagaaagaaa ugaugcuaag aaugccguug aagaauaugu auaugauuuu agagacaggc     1980

ugggcacugu cuaugaaaaa uucaucacuc cagaagacuu gaguaaacug ucugcaguau     2040

uggaagacac agaaaauugg cuuuaugaag acggagagga ccaaccuaaa caaguuuaug     2100

uggauaagcu ucaagaacua aagaaauacg gccagccuau ucaaaugaag uacauggagc     2160

augaagagag accaaaagcc uuaaaugacu ugggaaaaaa gauccaacuu gucaugaaag     2220

ugauagaagc uuauagaaac aaggaugaaa gauaugauca ucuggauccu acugaaaugg     2280

aaaagguuga aaaauguauc agugaugcca ugaguuggcu gaauaguaag augaaugcac     2340

agaacaaacu aagucucacu caagauccug ugguaaaagu uucagaaaua guagcaaagu     2400

caaaggaacu ggauaauuuc uguaacccca ucauuuacaa gcccaaacca aaagcagaag     2460

uuccugaaga caaaccaaaa gcuaauagug aacacaaugg cccaauggau ggacagagug     2520

gaacugaaac uaaaucagau ucaacaaaag acagcucaca gcauacuaaa uccucuggag     2580

agauggaagu ggacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  6279
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (wt)

<400>  6279
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcucuccc ugguggccgc gaugcugcug cugcucagcg      120

cggcgcgggc cgaggaggag gacaagaagg aggacguggg cacggugguc ggcaucgacc      180

uggggaccac cuacuccugc gucggcgugu ucaagaacgg ccgcguggag aucaucgcca      240

acgaucaggg caaccgcauc acgccguccu augucgccuu cacuccugaa ggggaacguc      300

ugauuggcga ugccgccaag aaccagcuca ccuccaaccc cgagaacacg gucuuugacg      360

ccaagcggcu caucggccgc acguggaaug acccgucugu gcagcaggac aucaaguucu      420

ugccguucaa ggugguugaa aagaaaacua aaccauacau ucaaguugau auuggaggug      480

ggcaaacaaa gacauuugcu ccugaagaaa uuucugccau gguucucacu aaaaugaaag      540

aaaccgcuga ggcuuauuug ggaaagaagg uuacccaugc aguuguuacu guaccagccu      600

auuuuaauga ugcccaacgc caagcaacca aagacgcugg aacuauugcu ggccuaaaug      660

uuaugaggau caucaacgag ccuacggcag cugcuauugc uuauggccug gauaagaggg      720

agggggagaa gaacauccug guguuugacc uggguggcgg aaccuucgau gugucucuuc      780

ucaccauuga caaugguguc uucgaaguug uggccacuaa uggagauacu caucugggug      840

gagaagacuu ugaccagcgu gucauggaac acuucaucaa acuguacaaa aagaagacgg      900

gcaaagaugu caggaaagac aauagagcug ugcagaaacu ccggcgcgag guagaaaagg      960

ccaaacgggc ccugucuucu cagcaucaag caagaauuga aauugagucc uucuaugaag     1020

gagaagacuu uucugagacc cugacucggg ccaaauuuga agagcucaac auggaucugu     1080

uccggucuac uaugaagccc guccagaaag uguuggaaga uucugauuug aagaagucug     1140

auauugauga aauuguucuu guugguggcu cgacucgaau uccaaagauu cagcaacugg     1200

uuaaagaguu cuucaauggc aaggaaccau cccguggcau aaacccagau gaagcuguag     1260

cguauggugc ugcuguccag gcuggugugc ucucugguga ucaagauaca ggugaccugg     1320

uacugcuuga uguauguccc cuuacacuug guauugaaac ugugggaggu gucaugacca     1380

aacugauucc aaggaacaca guggugccua ccaagaaguc ucagaucuuu ucuacagcuu     1440

cugauaauca accaacuguu acaaucaagg ucuaugaagg ugaaagaccc cugacaaaag     1500

acaaucaucu ucuggguaca uuugaucuga cuggaauucc uccugcuccu cguggggucc     1560

cacagauuga agucaccuuu gagauagaug ugaaugguau ucuucgagug acagcugaag     1620

acaaggguac agggaacaaa aauaagauca caaucaccaa ugaccagaau cgccugacac     1680

cugaagaaau cgaaaggaug guuaaugaug cugagaaguu ugcugaggaa gacaaaaagc     1740

ucaaggagcg cauugauacu agaaaugagu uggaaagcua ugccuauucu cuaaagaauc     1800

agauuggaga uaaagaaaag cugggaggua aacuuuccuc ugaagauaag gagaccaugg     1860

aaaaagcugu agaagaaaag auugaauggc uggaaagcca ccaagaugcu gacauugaag     1920

acuucaaagc uaagaagaag gaacuggaag aaauuguuca accaauuauc agcaaacucu     1980

auggaagugc aggcccuccc ccaacuggug aagaggauac agcagaaaaa gaugaguugu     2040

agggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  6280
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (wt)

<400>  6280
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccac gggagcucgc ggugggcauc gaccugggca      120

ccaccuacuc gugcgugggc guguuucagc agggccgcgu ggagauccug gccaacgacc      180

agggcaaccg caccacgccc agcuacgugg ccuucaccga caccgagcgg cuggucgggg      240

acgcggccaa gagccaggcg gcccugaacc cccacaacac cguguucgau gccaagcggc      300

ugaucgggcg caaguucgcg gacaccacgg ugcagucgga caugaagcac uggcccuucc      360

ggguggugag cgagggcggc aagcccaagg ugcgcguaug cuaccgcggg gaggacaaga      420

cguucuaccc cgaggagauc ucguccaugg ugcugagcaa gaugaaggag acggccgagg      480

cguaccuggg ccagcccgug aagcacgcag ugaucaccgu gcccgccuau uucaaugacu      540

cgcagcgcca ggccaccaag gacgcggggg ccaucgcggg gcucaacgug uugcggauca      600

ucaaugagcc cacggcagcu gccaucgccu augggcugga ccggcggggc gcgggagagc      660

gcaacgugcu cauuuuugac cugggugggg gcaccuucga ugugucgguu cucuccauug      720

acgcuggugu cuuugaggug aaagccacug cuggagauac ccaccuggga ggagaggacu      780

ucgacaaccg gcucgugaac cacuucaugg aagaauuccg gcggaagcau gggaaggacc      840

ugagcgggaa caagcgugcc cugcgcaggc ugcgcacagc cugugagcgc gccaagcgca      900

cccuguccuc cagcacccag gccacccugg agauagacuc ccuguucgag ggcguggacu      960

ucuacacguc caucacucgu gcccgcuuug aggaacugug cucagaccuc uuccgcagca     1020

cccuggagcc gguggagaag gcccugcggg augccaagcu ggacaaggcc cagauucaug     1080

acgucguccu gguggggggc uccacacgca uccccaaggu gcagaaguug cugcaggacu     1140

ucuucaacgg caaggagcug aacaagagca ucaacccuga ugaggcugug gccuaugggg     1200

cugcugugca ggcggccgug uugauggggg acaaauguga gaaagugcag gaucuccugc     1260

ugcuggaugu ggcuccccug ucucuggggc uggagacagc agguggggug augaccacgc     1320

ugauccagag gaacgccacu auccccacca agcagaccca gacuuucacc accuacucgg     1380

acaaccagcc uggggucuuc auccaggugu augaggguga gagggccaug accaaggaca     1440

acaaccugcu ggggcguuuu gaacucagug gcaucccucc ugccccacgu ggaguccccc     1500

agauagaggu gacuuuugac auugaugcua auggcauccu gagcgugaca gccacugaca     1560

ggagcacagg uaaggcuaac aagaucacca ucaccaauga caagggccgg cugagcaagg     1620

aggaggugga gaggaugguu caugaagccg agcaguacaa ggcugaggau gaggcccaga     1680

gggacagagu ggcugccaaa aacucgcugg aggcccaugu cuuccaugug aaagguucuu     1740

ugcaagagga aagccuuagg gacaagauuc ccgaagagga caggcgcaaa augcaagaca     1800

agugucggga aguccuugcc uggcuggagc acaaccagcu ggcagagaag gaggaguaug     1860

agcaucagaa gagggagcug gagcaaaucu gucgccccau cuucuccagg cucuaugggg     1920

ggccuggugu cccugggggc agcaguugug gcacucaagc ccgccagggg gaccccagca     1980

ccggccccau cauugaggag guugauugag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  6281
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (wt)

<400>  6281
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccac gggagcucgc ggugggcauc gaccugggca      120

ccaccuacuc gugcgugggc guguuucagc agggccgcgu ggagauccug gccaacgacc      180

agggcaaccg caccacgccc agcuacgugg ccuucaccga caccgagcgg cuggucgggg      240

acgcggccaa gagccaggcg gcccugaacc cccacaacac cguguucgau gccaagcggc      300

ugaucgggcg caaguucgcg gacaccacgg ugcagucgga caugaagcac uggcccuucc      360

agguggugag cgagggcggc aagcccaagg ugcgcguaug cuaccgcggg gaggacaaga      420

cguucuaccc cgaggagauc ucguccaugg ugcugagcaa gaugaaggag acggccgagg      480

cguaccuggg ccagcccgug aagcacgcag ugaucaccgu gcccaccuau uucaguaacu      540

cgcagcgcca ggccaccaag gacgcggggg ccaucgcggg gcucaaggug cugccgauca      600

ucaaugaggc cacggcagca gccaucgccu augggcugga ccggcggggc gcgggaaagc      660

gcaacgugcu cauuuuugac cugggugggg gcaccuucga ugugucgguu cucuccauug      720

acgccggugu cuuugaggug aaagccacug cuggagauac ccaccuggga ggagaggacu      780

ucgacaaccg gcucgugaac cacuucaugg aagaauuccg gcggaagcau gggaaggacc      840

ugagcgggaa caagcgugcc cugcgcaggc ugcgcacagc cugugagcgc gccaagcgca      900

ccccguccuc cagcacccag gccacccugg agauagacuc ccuguucgag ggcguggacu      960

ucuacaaguc caucacucgu gcccgcuuug aggaacugug cucagaccuc uuccgcagca     1020

cccuggagcc gguggagaag gcccugcggg augccaagcu ggacaaggcc cagauucaug     1080

acuucguccu ggggggaggg cuccacucgc auccccaagg ugcagaaguu gcugcaggac     1140

uucuucaacg gcaaggagcu gaacaagagc aucaacccug aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  6282
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (wt)

<400>  6282
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccaagggac cugcaguugg uauugaucuu ggcaccaccu      120

acucuugugu ggguguuuuc cagcacggaa aagucgagau aauugccaau gaucagggaa      180

accgaaccac uccaagcuau gucgccuuua cggacacuga acgguugauc ggugaugccg      240

caaagaauca aguugcaaug aaccccacca acacaguuuu ugaugccaaa cgucugauug      300

gacgcagauu ugaugaugcu guuguccagu cugauaugaa acauuggccc uuuauggugg      360

ugaaugaugc uggcaggccc aagguccaag uagaauacaa gggagagacc aaaagcuucu      420

auccagagga ggugucuucu augguucuga caaagaugaa ggaaauugca gaagccuacc      480

uugggaagac uguuaccaau gcugugguca cagugccagc uuacuuuaau gacucucagc      540

gucaggcuac caaagaugcu ggaacuauug cuggucucaa uguacuuaga auuauuaaug      600

agccaacugc ugcugcuauu gcuuacggcu uagacaaaaa gguuggagca gaaagaaacg      660

ugcucaucuu ugaccuggga gguggcacuu uugauguguc aauccucacu auugaggaug      720

gaaucuuuga ggucaagucu acagcuggag acacccacuu ggguggagaa gauuuugaca      780

accgaauggu caaccauuuu auugcugagu uuaagcgcaa gcauaagaag gacaucagug      840

agaacaagag agcuguaaga cgccuccgua cugcuuguga acgugcuaag cguacccucu      900

cuuccagcac ccaggccagu auugagaucg auucucucua ugaaggaauc gacuucuaua      960

ccuccauuac ccgugcccga uuugaagaac ugaaugcuga ccuguuccgu ggcacccugg     1020

acccaguaga gaaagcccuu cgagaugcca aacuagacaa gucacagauu caugauauug     1080

uccugguugg ugguucuacu cguaucccca agauucagaa gcuucuccaa gacuucuuca     1140

auggaaaaga acugaauaag agcaucaacc cugaugaagc uguugcuuau ggugcagcug     1200

uccaggcagc caucuugucu ggagacaagu cugagaaugu ucaagauuug cugcucuugg     1260

augucacucc ucuuucccuu gguauugaaa cugcuggugg agucaugacu guccucauca     1320

agcguaauac caccauuccu accaagcaga cacagaccuu cacuaccuau ucugacaacc     1380

agccuggugu gcuuauucag guuuaugaag gcgagcgugc caugacaaag gauaacaacc     1440

ugcuuggcaa guuugaacuc acaggcauac cuccugcacc ccgagguguu ccucagauug     1500

aagucacuuu ugacauugau gccaauggua uacucaaugu cucugcugug gacaagagua     1560

cgggaaaaga gaacaagauu acuaucacua augacaaggg ccguuugagc aaggaagaca     1620

uugaacguau gguccaggaa gcugagaagu acaaagcuga agaugagaag cagagggaca     1680

aggugucauc caagaauuca cuugaguccu augccuucaa caugaaagca acuguugaag     1740

augagaaacu ucaaggcaag auuaacgaug aggacaaaca gaagauucug gacaagugua     1800

augaaauuau caacuggcuu gauaagaauc agacugcuga gaaggaagaa uuugaacauc     1860

aacagaaaga gcuggagaaa guuugcaacc ccaucaucac caagcuguac cagagugcag     1920

gaggcaugcc aggaggaaug ccugggggau uuccuggugg uggagcuccu cccucuggug     1980

gugcuuccuc agggcccacc auugaagagg uugauuaagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  6283
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (wt)

<400>  6283
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaagugcca gccgagcugc agcagcccgu cucgugggcg      120

ccgcagccuc ccggggcccu acggccgccc gccaccagga uagcuggaau ggccuuaguc      180

augaggcuuu uagacuuguu ucaaggcggg auuaugcauc agaagcaauc aagggagcag      240

uuguugguau ugauuugggu acuaccaacu ccugcguggc aguuauggaa gguaaacaag      300

caaaggugcu ggagaaugcc gaaggugcca gaaccacccc uucaguugug gccuuuacag      360

cagaugguga gcgacuuguu ggaaugccgg ccaagcgaca ggcugucacc aacccaaaca      420

auacauuuua ugcuaccaag cgucucauug gccggcgaua ugaugauccu gaaguacaga      480

aagacauuaa aaauguuccc uuuaaaauug uccgugccuc caauggugau gccuggguug      540

aggcucaugg gaaauuguau ucuccgaguc agauuggagc auuuguguug augaagauga      600

aagagacugc agaaaauuac uuggggcaca cagcaaaaaa ugcugugauc acagucccag      660

cuuauuucaa ugacucgcag agacaggcca cuaaagaugc uggccagaua ucuggacuga      720

augugcuucg ggugauuaau gagcccacag cugcugcucu ugccuauggu cuagacaaau      780

cagaagacaa agucauugcu guauaugauu uagguggugg aacuuuugau auuucuaucc      840

uggaaauuca gaaaggagua uuugagguga aauccacaaa uggggauacc uucuuaggug      900

gggaagacuu ugaccaggcc uugcuacggc acauugugaa ggaguucaag agagagacag      960

ggguugauuu gacuaaagac aacauggcac uucagagggu acgggaagcu gcugaaaagg     1020

cuaaauguga acucuccuca ucugugcaga cugacaucaa uuugcccuau cuuacaaugg     1080

auucuucugg acccaagcau uugaauauga aguugacccg ugcucaauuu gaagggauug     1140

ucacugaucu aaucagaagg acuaucgcuc caugccaaaa agcuaugcaa gaugcagaag     1200

ucagcaagag ugacauagga gaagugauuc uugugggugg caugacuagg augcccaagg     1260

uucagcagac uguacaggau cuuuuuggca gagccccaag uaaagcuguc aauccugaug     1320

aggcuguggc cauuggagcu gccauucagg gagguguguu ggccggcgau gucacggaug     1380

ugcugcuccu ugaugucacu ccccugucuc uggguauuga aacucuagga ggugucuuua     1440

ccaaacuuau uaauaggaau accacuauuc caaccaagaa gagccaggua uucucuacug     1500

ccgcugaugg ucaaacgcaa guggaaauua aaguguguca gggugaaaga gagauggcug     1560

gagacaacaa acuccuugga caguuuacuu ugauuggaau uccaccagcc ccucguggag     1620

uuccucagau ugaaguuaca uuugacauug augccaaugg gauaguacau guuucugcua     1680

aagauaaagg cacaggacgu gagcagcaga uuguaaucca gucuucuggu ggauuaagca     1740

aagaugauau ugaaaauaug guuaaaaaug cagagaaaua ugcugaagaa gaccggcgaa     1800

agaaggaacg aguugaagca guuaauaugg cugaaggaau cauucacgac acagaaacca     1860

agauggaaga auucaaggac caauuaccug cugaugagug caacaagcug aaagaagaga     1920

uuuccaaaau gagggagcuc cuggcuagaa aagacagcga aacaggagaa aauauuagac     1980

aggcagcauc cucucuucag caggcaucac ugaagcuguu cgaaauggca uacaaaaaga     2040

uggcaucuga gcgagaaggc ucuggaaguu cuggcacugg ggaacaaaag gaagaucaaa     2100

aggaggaaaa acaguaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  6284
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (wt)

<400>  6284
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcggacaagg aggccggcgg cagcgacggg ccccgagaaa      120

cggcucccac aucugcauau ucaucuccag cccggagucu uggggacaca ggaauaacgc      180

cucugucccc cucccauauu gugaacgaca cugacuccaa cgucucagaa cagcagucau      240

uucucguggu gguggccguc gacuuuggga ccacauccag uggcuaugcc uacagcuuca      300

ccaaggagcc ggaaugcauc caugugauga ggcgauggga gggaggugac ccuggugugu      360

ccaaucagaa gacuccaacc accaucuugc ugacucccga gaggaaguuc cacagcuucg      420

gguaugccgc cagggacuuu uaccaugacc uggaucccaa ugaggccaag caguggcugu      480

accuggagaa guucaagaug aagcugcaca ccacugggga ccucaccaug gauacagacc      540

ugacggcagc aaauggcaag aaagucaaag cccuugaaau cuuugcuuau gcccugcagu      600

acuuuaagga gcaggcgcug aaggagcuga gugaccaggc ggguucggag uucgagaacu      660

cugaugucag augggucauc acggugccug ccaucuggaa gcagccggcc aagcaguuca      720

ugagacaagc ugccuaccag gcaggccugg ccucccccga gaacucggag cagcucauca      780

uugccuugga gccugaggca gccucuaucu acugccgaaa gcugcggcua caccagauga      840

uugagcugag cagcaaggca gccgucaaug gguacagcgg cagugacaca guaggagcug      900

gguuuacaca ggcuaaggaa cacauacggc guaaucggca gagucggacc uuuuuggugg      960

agaaugucau aggagaaauc ugguccgagc uggaggaagg ugauaaguau gugguugugg     1020

acaguggcgg uggcaccgua gaccugacag uccaucagau ccgguuaccg gagggacacc     1080

uuaaggaacu guauaaagca acaggcggac ccuauggauc uuuaggagua gauuaugagu     1140

ucgaaaaacu ucuguauaaa auauuuggag aggauuuuau ugaacaauuc aaaaucaaac     1200

gcccugcagc cuggguugac uuaaugauug cguuugaguc ucgcaaaagg gcggcugccc     1260

cagacagaac uaacccgcug aacaucaccc ugcccuucuc cuucauugac uacuacaaga     1320

aguuccgcgg gcacagugug gagcacgccu ugcggaaaag caauguggau uuugugaagu     1380

gguccucgca ggggaugcug cggaugaguc cagaugccau gaacgcccuu uuuaagccga     1440

ccaucgauag caucauugag caucuccggg accuguuuca gaagcccgag guguccaccg     1500

ucaaguuccu cuuucuggug ggcggcuuug ccgaggcgcc ccugcugcag caggcggugc     1560

aggcugcuuu uggggaccag ugccggauca ucauccccca ggacgugggc cucaccaucc     1620

ucaagggugc cguccucuuu ggccuggacc ccgcggucau caaggugcgc cggucgccgc     1680

ucaccuacgg gguaggcgug cugaaccgcu acguggaggg caagcacccg ccugagaagc     1740

ugcuggugaa ggauggcacu cgguggugca ccgacgucuu ugacaaguuc aucucugccg     1800

accagucugu ggcucugggu gagcugguca agcguagcua caccccggcc aagcccuccc     1860

agcuggucau ugucaucaac aucuacagcu cugagcacga caacgucagc uucaucacug     1920

aucccggggu gaagaagugu ggcacgcucc gccuggaucu cacagggacc aguggcacug     1980

cggugcccgc ccggagggag auccagaccc uuaugcaguu cggggacacc gagaucaaag     2040

ccacagccau ugauauagcc acuucgaaga gugucaaagu ugggaucgac uucuuaaauu     2100

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  6285
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (wt)

<400>  6285
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuggcugucc cggagauggg ccugcagggg cuguacaucg      120

gcuccagccc ggagcggucc ccagugccua gcccacccgg cuccccgagg acccaggaaa      180

gcugcggcau ugccccccuc acacccucgc agucuccaaa acccgagguc cgagcccccc      240

agcaggccuc cuucucugug gugguggcca uugacuucgg caccacgucu aguggcuaug      300

cuuucagcuu ugccagugac ccugaggcca uccacaugau gaggaaaugg gagggcggag      360

acccgggcgu ggcccaccag aagaccccga ccugccugcu gcugacuccg gagggcgccu      420

uccacagcuu uggcuacacc gcccgcgauu acuaccauga ccuggacccc gaagaggcgc      480

gggacuggcu cuacuucgag aaguucaaga ugaagaucca cagcgccacg gaucucaccu      540

ugaagaccca gcuagaggca guaaauggaa agacgaugcc cgcccuggag guguucgccc      600

augcccugcg cuucuucagg gagcacgccc uucaggagcu gagggagcag agcccaucgc      660

ugccagagaa ggacacugug cgcugggugu ugacggugcc ugccaucugg aaacagccag      720

ccaagcaguu caugcgggag gcugccuacc uggcuggacu agugucccga gagaaugcag      780

agcagcuacu caucgcccug gagcccgagg ccgccucggu auacugccgc aagcugcgcc      840

ugcaccagcu ccuggaccug aguggccggg ccccaggugg ugggcgccug ggugagcgcc      900

gcuccaucga cuccagcuuc cgucaggcuc gggagcagcu gcgaaggucc cgccacagcc      960

gcacguuccu gguggaguca ggcguaggag agcugugggc agagaugcaa gcaggagacc     1020

gcuacguggu ggccgacugc ggcggaggca ccguggaccu gacggugcac cagcuggagc     1080

agccccaugg cacccucaag gagcucuaca aggcaucugg gggcccuuau ggcgcggugg     1140

gcguggaccu ggccuucgag cagcugcugu gccgcaucuu cggcgaggac uucaucgcca     1200

ccuucaaaag gcaacggccg gcagccuggg uagaucugac caucgccuuc gaggcucgca     1260

agcgcacugc uggcccacac cgugcagggg cgcucaacau cucgcugccc uucuccuuca     1320

uugacuucua ccgcaagcag cggggccaca acguggagac cgcucugcgc aggagcagcg     1380

ugaacuucgu gaaguggucc ucacagggga ugcuccgaau gucuugugaa gccaugaacg     1440

agcucuuuca gcccaccguc agcgggauca uccagcacau agaggcccug cuggcacggc     1500

cggaggugca gggugugaag cugcuguucc uagugggcgg cuucgccgag ucagcggugc     1560

ugcagcacgc ggugcaggcg gcgcugggcg cccgcggucu gcgugucgug gucccgcacg     1620

acgugggccu caccauccuc aaaggcgcgg ugcuguucgg ccaggcgccg ggcguggugc     1680

ggguccgccg cucgccgcuc accuauggcg ugggcgugcu caaccgcuuu gugccugggc     1740

gccacccgcc cgaaaagcug cugguucgcg acggccgccg cuggugcacc gacgucuucg     1800

agcgcuucgu ggccgccgag cagucggugg cccugggcga ggaggugcgg cgcagcuacu     1860

gcccggcgcg ucccggccag cggcgcguac ucaucaaccu guacugcugc gcggcagagg     1920

augcgcgcuu caucaccgac cccggcgugc gcaaaugcgg cgcgcucagc cucgagcuug     1980

agcccgccga cugcggccag gacaccgccg gcgcgccucc cggccgccgc gagauccgcg     2040

ccgccaugca guuuggcgac accgaaauua aggucaccgc cgucgacguc agcaccaauc     2100

gcuccgugcg cgcguccauc gacuuucuuu ccaacugagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  6286
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (wt)

<400>  6286
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagagaga ugacgaucuu aggaucggcu guuuugacuc      120

uccuguuggc cggcuauuug gcacaacagu auuuaccauu gccuacuccu aaagugauug      180

guauugaucu uggcaccacc uauuguucug uugggguguu uuuuccuggc acaggaaaag      240

uaaaggugau uccagaugaa aaugggcaua ucagcauacc cagcauggug ucuuuuacug      300

acaaugaugu auauguggga uaugaaagcg uagagcuggc agauucaaau ccucaaaaca      360

caauauauga ugccaaaaga uucauaggca agauuuuuac cgcagaagag uuggaggcug      420

aaauuggcag auacccauuu aagguuuuaa acaaaaaugg aaugguugag uuuucuguga      480

caaguaauga gaccaucaca guguccccag aauauguugg cucucgacua uuguugaagu      540

uaaaggaaau ggcagaggca uaucuuggaa ugccaguugc caaugcuguc auuucuguac      600

cagcagaauu ugaucuaaaa cagagaaauu caacaauuga agcugcuaac cuugcaggac      660

ugaagauuuu gaggguaaua aaugaaccca cagcagcagc uauggccuau ggucuccaca      720

aggcugacgu cuuccacguc uuggugauag acuugggcgg aggaacucua gaugugucuu      780

uacugaauaa acaaggaggg auguuucuaa cccgagcaau gucuggaaac aauaaacuug      840

gaggacagga cuucaaucag agauugcuuc aguacuuaua uaaacagauc uaucaaacau      900

auggcuucgu gcccucuagg aaagaggaaa uccacagauu gagacaagcu guggaaaugg      960

ucaaauuaaa ucugacucuu caucaaucug cucaguuguc aguauuacua acgguggagg     1020

agcaggacag gaaggaaccu cacaguagug acacugaacu gccaaaagac aaacuuuccu     1080

cagcagauga ccaucgcgug aacagugggu uuggacgugg ccuuucugau aagaaaagug     1140

gagaaaguca gguuuuauuu gaaacagaaa uaucacggaa acucuuugau acccuuaaug     1200

aagaccucuu ucagaaaaua cugguaccca uucagcaagu auugaaagaa ggccaccugg     1260

aaaagacuga gauugaugag gugguuuuag uugggggcuc cacucguauu ccucggaucc     1320

gucaagucau ucaagaguuc uuuggaaaag aucccaacac aucuguagac ccugaccuag     1380

caguaguaac gggaguggcu auccaagcag ggauugaugg aggcucuugg ccucuccaag     1440

ucagugcuuu agaaauuccc aauaagcauu uacaaaaaac caacuucaac ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6287
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (wt)

<400>  6287
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcggccaucg gaguucaccu gggcugcacc ucagccugug      120

uggccgucua uaaggauggc cgggcuggug ugguugcaaa ugaugccggu gaccgaguua      180

cuccagcugu uguugcuuac ucagaaaaug aagagauugu uggauuggca gcaaaacaaa      240

guagaauaag aaauauuuca aauacaguaa ugaaaguaaa gcagauccug ggcagaagcu      300

ccagugaucc acaagcucag aaauacaucg cggaaaguaa auguuuaguc auugaaaaaa      360

augggaaauu acgauaugaa auagauacug gagaagaaac aaaauuuguu aacccagaag      420

auguugccag acugauauuu aguaaaauga aagaaacggc acauucugua uugggcucag      480

augcaaauga uguaguuauu acugucccgu uugauuuugg agaaaagcaa aaaaaugcuc      540

uuggagaagc agcuagagcu gcuggauuua auguuuugcg auuaauucac gaaccgucug      600

cagcucuucu ugcuuaugga auuggacaag acuccccuac uggaaaaagc aauauuuugg      660

uguuuaagcu uggaggaaca uccuuaucuc ucagcgucau ggaaguuaac aguggaauau      720

aucggguucu uucaacaaac acugaugaua acaucggugg ugcacauuuc acagaaaccu      780

uagcacagua ucuagcuucu gaguuccaaa gauccuucaa acaugaugug agaggaaaug      840

cgcgagccau gaugaaauua acgaacagug cugaaguagc gaaacauucu uugucaaccu      900

ugggaagugc caacuguuuu cuugacucau uauaugaagg ucaagauuuu gauugcaaug      960

uguccagagc aagauuugaa cuucuuuguu cuccacuuuu uaauaagugu auagaagcaa     1020

ucagaggacu cuuagaucaa aauggauuua cagcagauga uaucaacaag guuguccuuu     1080

guggaggguc uucucgaauc ccaaagcuac agcaacugau uaaagaucuu uucccagcug     1140

uugagcuucu caauucuauc ccuccugaug aagugauccc uauuggugca gcuauagaag     1200

caggaauucu uauugggaaa gaaaaccugu ugguggaaga cucucuuaug auagaguguu     1260

cagccagaga uauuuuaguu aagggugugg acgaaucagg agccaguaga uucacagugc     1320

uguuuccauc agggacuccu uugccagcuc gaagacaaca cacauugcaa gccccuggaa     1380

gcauaucuuc agugugccuu gaacucuaug agucugaugg gaagaacucu gccaaagagg     1440

aaaccaaguu ugcacagguu guacuccagg auuuagauaa aaaagaaaau ggauuacgug     1500

auauauuagc uguucuuacu augaaaaggg auggaucuuu acaugugaca ugcacagauc     1560

aagaaacugg aaaaugugaa gcaaucucua uugagauagc aucuuaggga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  6288
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (wt)

<400>  6288
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucgguggugg gguuggacgu gggcucgcag agcugcuaca      120

ucgcgguagc ccgggccggg ggcaucgaga ccaucgccaa ugaguucagc gaccggugca      180

ccccgucagu cauaucauuu ggaucaaaaa auagaacaau cggaguugca gccaaaaauc      240

agcaaaucac ucaugcaaac aauacggugu cuaacuucaa aagauuucau ggccgagcau      300

ucaaugaccc cuucauucaa aaggagaagg aaaacuugag uuacgauuug guuccauuga      360

aaaauggugg aguuggaaua aagguaaugu acauggguga agaacaucua uuuagugugg      420

agcagauaac agccauguug uugacuaagc ugaaggaaac ugcugaaaac agccucaaga      480

aaccaguaac agauuguguu auuucagucc ccuccuucuu uacagaugcu gagaggcgau      540

cuguguuaga ugcugcacag auuguuggcc uaaacuguuu aagacuuaug aaugacauga      600

cagcuguugc uuugaauuac ggaauuuaua agcaggaucu cccaagccug gaugagaaac      660

cucggauagu gguuuuuguu gauaugggac auucagcuuu ucaagugucu gcuugugcuu      720

uuaacaaggg aaaauugaag guacugggaa cagcuuuuga uccuuucuua ggaggaaaaa      780

acuucgauga aaaguuagug gaacauuuuu gugcagaauu uaaaacuaag uacaaguugg      840

augcaaaauc caaaauacga gcacuccuac gucuguauca ggaaugugaa aaacugaaaa      900

agcuaaugag cucuaacagc acagaccuuc cacugaauau cgaaugcuuu augaaugaua      960

aagauguuuc cggaaagaug aacaggucac aauuugaaga acucugugcu gaacuucugc     1020

aaaagauaga aguaccccuu uauucacugu uggaacaaac ucaucucaaa guagaagaug     1080

ugagugcagu ugagauuguu ggaggcgcua cacgaauucc agcugugaag gaaagaauug     1140

ccaaauucuu uggaaaagau auuagcacaa cacucaaugc agaugaagca guagccagag     1200

gaugugcauu acagugugca auacuuuccc cggcauuuaa aguuagagaa uuuuccguca     1260

cagaugcagu uccuuuucca auaucucuga ucuggaacca ugauucagaa gauacugaag     1320

guguucauga agucuuuagu cgaaaccaug cugcuccuuu cuccaaaguu cucaccuuuc     1380

ugagaagggg gccuuuugag cuagaagcuu ucuauucuga uccccaagga guuccauauc     1440

cagaagcaaa aauaggccgc uuuguaguuc agaauguuuc ugcacagaaa gauggagaaa     1500

aaucuagagu aaaagucaaa gugcgaguca acacccaugg cauuuucacc aucucuacgg     1560

caucuauggu ggagaaaguc ccaacugagg agaaugaaau gucuucugaa gcugacaugg     1620

agugucugaa ucagagacca ccagaaaacc cagacacuga uaaaaauguc cagcaagaca     1680

acagugaagc uggaacacag ccccagguac aaacugaugc ucaacaaacc ucacagucuc     1740

ccccuucacc ugaacuuacc ucagaagaaa acaaaauccc agaugcugac aaagcaaaug     1800

aaaaaaaagu ugaccagccu ccagaagcua aaaagcccaa aauaaaggug gugaauguug     1860

agcugccuau ugaagccaac uuggucuggc aguuagggaa agaccuucuu aacauguaua     1920

uugagacaga ggguaagaug auaaugcaag auaaauugga aaaagaaagg aaugaugcua     1980

aaaaugcagu ugaggaauau guguaugagu ucagagacaa gcugugugga ccauaugaaa     2040

aauuuauaug ugagcaggau caucaaaauu uuuugagacu ccucacagaa acugaagacu     2100

ggcuguauga agaaggagag gaccaagcua aacaagcaua uguugacaag uuggaagaau     2160

uaaugaaaau uggcacucca guuaaaguuc gguuucagga agcugaagaa cggccaaaaa     2220

uguuugaaga acuaggacag aggcugcagc auuaugccaa gauagcagcu gacuucagaa     2280

auaaggauga gaaauacaac cauauugaug agucugaaau gaaaaaagug gagaagucug     2340

uuaaugaagu gauggaaugg augaauaaug ucaugaaugc ucaggcuaaa aagagucuug     2400

aucaggaucc aguuguacgu gcucaggaaa uuaaaacaaa aaucaaggaa uugaacaaca     2460

caugugaacc cguuguaaca caaccgaaac caaaaauuga aucacccaaa cuggaaagaa     2520

cuccaaaugg cccaaauauu gauaaaaagg aagaagauuu agaagacaaa aacaauuuug     2580

gugcugaacc uccacaucag aauggugaau guuacccuaa ugagaaaaau ucuguuaaua     2640

uggacuugga cuagggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  6289
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (wt)

<400>  6289
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagacaaag uuaggaggca gaggccgagg aggcgagucu      120

guugggccuu gguggcugug cucuuggcag accuguuggc acugagugau acacuggcag      180

ugaugucugu ggaccugggc agugagucca ugaagguggc cauugucaaa ccuggagugc      240

ccauggaaau ugucuugaau aaggaaucuc ggaggaaaac accggugauc gugacccuga      300

aagaaaauga aagauucuuu ggagacagug cagcaagcau ggcgauuaag aauccaaagg      360

cuacgcuacg uuacuuccag caccuccugg ggaagcaggc agauaacccc cauguagcuc      420

uuuaccaggc ccgcuucccg gagcacgagc ugacuuucga cccacagagg cagacugugc      480

acuuucagau cagcucgcag cugcaguucu caccugagga aguguugggc augguucuca      540

auuauucucg uucucuagcu gaagauuuug cagagcagcc caucaaggau gcagugauca      600

ccgugccagu cuucuucaac caggccgagc gccgagcugu gcugcaggcu gcucguaugg      660

cuggccucaa agugcugcag cucaucaaug acaacaccgc cacugcccuc agcuauggug      720

ucuuccgccg gaaagauauu aacaccacug cccagaauau cauguucuau gacaugggcu      780

caggcagcac cguaugcacc auugugaccu accagauggu gaagacuaag gaagcuggga      840

ugcagccaca gcugcagauc cggggaguag gauuugaccg uacccugggg ggccuggaga      900

uggagcuccg gcuucgagaa cgccuggcug ggcuuuucaa ugagcagcgc aagggucaga      960

gagcaaagga ugugcgggag aacccgcgug ccauggccaa gcugcugcgu gaggcuaauc     1020

ggcucaaaac cguccucagu gccaacgcug accacauggc acagauugaa ggccugaugg     1080

augaugugga cuucaaggca aaagugacuc guguggaauu ugaggaguug ugugcagacu     1140

uguuugagcg ggugccuggg ccuguacagc aggcccucca gagugccgaa augagucugg     1200

augagauuga gcaggugauc cuggugggug gggccacucg gguccccaga guucaggagg     1260

ugcugcugaa ggccgugggc aaggaggagc uggggaagaa caucaaugca gaugaagcag     1320

ccgccauggg ggcaguguac caggcagcug cgcucagcaa agccuuuaaa gugaagccau     1380

uugucguccg agaugcagug gucuacccca uccuggugga guucacgagg gagguggagg     1440

aggagccugg gauucacagc cugaagcaca auaaacgggu acucuucucu cggauggggc     1500

ccuacccuca acgcaaaguc aucaccuuua accgcuacag ccaugauuuc aacuuccaca     1560

ucaacuacgg cgaccugggc uuccuggggc cugaagaucu ucggguauuu ggcucccaga     1620

aucugaccac agugaagcua aaaggggugg gugacagcuu caagaaguau ccugacuacg     1680

aguccaaggg caucaaggcu cacuucaacc uggaugagag uggcgugcuc agucuagaca     1740

ggguggaguc uguauuugag acacugguag aggacagcgc agaagaggaa ucuacucuca     1800

ccaaacuugg caacaccauu uccagccugu uuggaggcgg uaccacacca gaugccaagg     1860

agaaugguac ugauacuguc caggaggaag aggagagccc ugcagagggg agcaaggacg     1920

agccugggga gcagguggag cucaaggagg aagcugaggc cccaguggag gauggcucuc     1980

agcccccacc cccugaaccu aagggagaug caaccccuga gggagaaaag gccacagaaa     2040

aagaaaaugg ggacaagucu gaggcccaga aaccaaguga gaaggcagag gcagggccug     2100

agggcgucgc uccagcccca gagggagaga agaagcagaa gcccgccagg aagcggcgaa     2160

ugguagagga gaucggggug gagcugguug uucuggaccu gccugacuug ccagaggaua     2220

agcuggcuca gucggugcag aaacuucagg acuugacacu ccgagaccug gagaagcagg     2280

aacgggaaaa agcugccaac agcuuggaag cauucauauu ugagacccag gacaagcugu     2340

accagcccga guaccaggaa guguccacag aggagcagcg ugaggagauc ucugggaagc     2400

ucagcgccgc auccaccugg cuggaggaug aggguguugg agccaccaca gugauguuga     2460

aggagaagcu ggcugagcug aggaagcugu gccaagggcu guuuuuucgg guagaggagc     2520

gcaagaagug gcccgaacgg cugucugccc ucgauaaucu ccucaaccau uccagcaugu     2580

uccucaaggg ggcccggcuc aucccagaga uggaccagau cuucacugag guggagauga     2640

caacguuaga gaaagucauc aaugagaccu gggccuggaa gaaugcaacu cuggccgagc     2700

aggcuaagcu gcccgccaca gagaagccug uguugcucuc aaaagacauu gaagcuaaga     2760

ugauggcccu ggaccgagag gugcaguauc ugcucaauaa ggccaaguuu accaagcccc     2820

ggccccggcc uaaggacaag aaugggaccc gggcagagcc accccucaau gccagugcca     2880

gugaccaggg ggagaagguc aucccuccag caggccagac ugaagaugca gagcccauuu     2940

cagaaccuga gaaaguagag acuggauccg agccaggaga cacugagccu uuggaguuag     3000

gagguccugg agcagaaccu gaacagaaag aacaaucgac aggacagaag cggccuuuga     3060

agaacgacga acuauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6290
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (wt)

<400>  6290
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccugaggaaa cccagaccca agaccaaccg auggaggagg      120

aggagguuga gacguucgcc uuucaggcag aaauugccca guugauguca uugaucauca      180

auacuuucua cucgaacaaa gagaucuuuc ugagagagcu cauuucaaau ucaucagaug      240

cauuggacaa aauccgguau gaaagcuuga cagaucccag uaaauuagac ucugggaaag      300

agcugcauau uaaccuuaua ccgaacaaac aagaucgaac ucucacuauu guggauacug      360

gaauuggaau gaccaaggcu gacuugauca auaaccuugg uacuaucgcc aagucuggga      420

ccaaagcguu cauggaagcu uugcaggcug gugcagauau cucuaugauu ggccaguucg      480

guguugguuu uuauucugcu uauuugguug cugagaaagu aacugugauc accaaacaua      540

acgaugauga gcaguacgcu ugggaguccu cagcaggggg aucauucaca gugaggacag      600

acacagguga accuaugggu cguggaacaa aaguuauccu acaccugaaa gaagaccaaa      660

cugaguacuu ggaggaacga agaauaaagg agauugugaa gaaacauucu caguuuauug      720

gauaucccau uacucuuuuu guggagaagg aacgugauaa agaaguaagc gaugaugagg      780

cugaagaaaa ggaagacaaa gaagaagaaa aagaaaaaga agagaaagag ucggaagaca      840

aaccugaaau ugaagauguu gguucugaug aggaagaaga aaagaaggau ggugacaaga      900

agaagaagaa gaagauuaag gaaaaguaca ucgaucaaga agagcucaac aaaacaaagc      960

ccaucuggac cagaaauccc gacgauauua cuaaugagga guacggagaa uucuauaaga     1020

gcuugaccaa ugacugggaa gaucacuugg cagugaagca uuuuucaguu gaaggacagu     1080

uggaauucag agcccuucua uuugucccac gacgugcucc uuuugaucug uuugaaaaca     1140

gaaagaaaaa gaacaacauc aaauuguaug uacgcagagu uuucaucaug gauaacugug     1200

aggagcuaau cccugaauau cugaacuuca uuagaggggu gguagacucg gaggaucucc     1260

cucuaaacau aucccgugag auguugcaac aaagcaaaau uuugaaaguu aucaggaaga     1320

auuuggucaa aaaaugcuua gaacucuuua cugaacuggc ggaagauaaa gagaacuaca     1380

agaaauucua ugagcaguuc ucuaaaaaca uaaagcuugg aauacacgaa gacucucaaa     1440

aucggaagaa gcuuucagag cuguuaaggu acuacacauc ugccucuggu gaugagaugg     1500

uuucucucaa ggacuacugc accagaauga aggagaacca gaaacauauc uauuauauca     1560

caggugagac caaggaccag guagcuaacu cagccuuugu ggaacgucuu cggaaacaug     1620

gcuuagaagu gaucuauaug auugagccca uugaugagua cuguguccaa cagcugaagg     1680

aauuugaggg gaagacuuua gugucaguca ccaaagaagg ccuggaacuu ccagaggaug     1740

aagaagagaa aaagaagcag gaagagaaaa aaacaaaguu ugagaaccuc ugcaaaauca     1800

ugaaagacau auuggagaaa aaaguugaaa aggugguugu gucaaaccga uuggugacau     1860

cuccaugcug uauugucaca agcacauaug gcuggacagc aaacauggag agaaucauga     1920

aagcucaagc ccuaagagac aacucaacaa uggguuacau ggcagcaaag aaacaccugg     1980

agauaaaccc ugaccauucc auuauugaga ccuuaaggca aaaggcagag gcugauaaga     2040

acgacaaguc ugugaaggau cuggucaucu ugcuuuauga aacugcgcuc cugucuucug     2100

gcuucagucu ggaagauccc cagacacaug cuaacaggau cuacaggaug aucaaacuug     2160

gucuggguau ugaugaagau gacccuacug cugaugauac cagugcugcu guaacugaag     2220

aaaugccacc ccuugaagga gaugacgaca caucacgcau ggaagaagua gacuaaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  6291
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (wt)

<400>  6291
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gauuccagua aauuagacuc ugggaaaggg cugcauauua      120

accuuguacc aaacaaacaa aaucaaaccc ucacuauugu ggacacuaga auuggaauga      180

ccaagacuga cuugaucaau aaccucggua cugucaccaa gucugggacc aaagcauuca      240

uggaagcuuu gcaggcugau gcagauaucu cuaugauugg ccauuucggg guugguuuuu      300

auucugcuua uuugguugcc aagaaaguaa cugugaucag caaacauaac aaugaugagc      360

aguacaccug ggaguccuca gcagggggau cauucacagu gaggacagac gagugaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  6292
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (wt)

<400>  6292
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccugaggaag ugcaccaugg agaggaggag guggagacuu      120

uugccuuuca ggcagaaauu gcccaacuca ugucccucau caucaauacc uucuauucca      180

acaaggagau uuuccuucgg gaguugaucu cuaaugcuuc ugaugccuug gacaagauuc      240

gcuaugagag ccugacagac ccuucgaagu uggacagugg uaaagagcug aaaauugaca      300

ucauccccaa cccucaggaa cguacccuga cuuugguaga cacaggcauu ggcaugacca      360

aagcugaucu cauaaauaau uugggaacca uugccaaguc ugguacuaaa gcauucaugg      420

aggcucuuca ggcuggugca gacaucucca ugauugggca guuugguguu ggcuuuuauu      480

cugccuacuu gguggcagag aaagugguug ugaucacaaa gcacaacgau gaugaacagu      540

augcuuggga gucuucugcu ggagguuccu ucacugugcg ugcugaccau ggugagccca      600

uuggcagggg uaccaaagug auccuccauc uuaaagaaga ucagacagag uaccuagaag      660

agaggcgggu caaagaagua gugaagaagc auucucaguu cauaggcuau cccaucaccc      720

uuuauuugga gaaggaacga gagaaggaaa uuagugauga ugaggcagag gaagagaaag      780

gugagaaaga agaggaagau aaagaugaug aagaaaaacc caagaucgaa gauguggguu      840

cagaugagga ggaugacagc gguaaggaua agaagaagaa aacuaagaag aucaaagaga      900

aauacauuga ucaggaagaa cuaaacaaga ccaagccuau uuggaccaga aacccugaug      960

acaucaccca agaggaguau ggagaauucu acaagagccu cacuaaugac ugggaagacc     1020

acuuggcagu caagcacuuu ucuguagaag gucaguugga auucagggca uugcuauuua     1080

uuccucgucg ggcucccuuu gaccuuuuug agaacaagaa gaaaaagaac aacaucaaac     1140

ucuauguccg ccguguguuc aucauggaca gcugugauga guugauacca gaguaucuca     1200

auuuuauccg uggugugguu gacucugagg aucugccccu gaacaucucc cgagaaaugc     1260

uccagcagag caaaaucuug aaagucauuc gcaaaaacau uguuaagaag ugccuugagc     1320

ucuucucuga gcuggcagaa gacaaggaga auuacaagaa auucuaugag gcauucucua     1380

aaaaucucaa gcuuggaauc cacgaagacu ccacuaaccg ccgccgccug ucugagcugc     1440

ugcgcuauca uaccucccag ucuggagaug agaugacauc ucugucagag uauguuucuc     1500

gcaugaagga gacacagaag uccaucuauu acaucacugg ugagagcaaa gagcaggugg     1560

ccaacucagc uuuuguggag cgagugcgga aacggggcuu cgagguggua uauaugaccg     1620

agcccauuga cgaguacugu gugcagcagc ucaaggaauu ugaugggaag agccuggucu     1680

caguuaccaa ggagggucug gagcugccug aggaugagga ggagaagaag aagauggaag     1740

agagcaaggc aaaguuugag aaccucugca agcucaugaa agaaaucuua gauaagaagg     1800

uugagaaggu gacaaucucc aauagacuug ugucuucacc uugcugcauu gugaccagca     1860

ccuacggcug gacagccaau auggagcgga ucaugaaagc ccaggcacuu cgggacaacu     1920

ccaccauggg cuauaugaug gccaaaaagc accuggagau caacccugac caccccauug     1980

uggagacgcu gcggcagaag gcugaggccg acaagaauga uaaggcaguu aaggaccugg     2040

uggugcugcu guuugaaacc gcccugcuau cuucuggcuu uucccuugag gauccccaga     2100

cccacuccaa ccgcaucuau cgcaugauca agcuaggucu agguauugau gaagaugaag     2160

uggcagcaga ggaacccaau gcugcaguuc cugaugagau ccccccucuc gagggcgaug     2220

aggaugcguc ucgcauggaa gaagucgauu agggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  6293
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (wt)

<400>  6293
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agggcccugu gggugcuggg ccucugcugc guccugcuga      120

ccuucggguc ggucagagcu gacgaugaag uugaugugga ugguacagua gaagaggauc      180

uggguaaaag uagagaagga ucaaggacgg augaugaagu aguacagaga gaggaagaag      240

cuauucaguu ggauggauua aaugcaucac aaauaagaga acuuagagag aagucggaaa      300

aguuugccuu ccaagccgaa guuaacagaa ugaugaaacu uaucaucaau ucauuguaua      360

aaaauaaaga gauuuuccug agagaacuga uuucaaaugc uucugaugcu uuagauaaga      420

uaaggcuaau aucacugacu gaugaaaaug cucuuucugg aaaugaggaa cuaacaguca      480

aaauuaagug ugauaaggag aagaaccugc ugcaugucac agacaccggu guaggaauga      540

ccagagaaga guugguuaaa aaccuuggua ccauagccaa aucugggaca agcgaguuuu      600

uaaacaaaau gacugaagca caggaagaug gccagucaac uucugaauug auuggccagu      660

uuggugucgg uuucuauucc gccuuccuug uagcagauaa gguuauuguc acuucaaaac      720

acaacaacga uacccagcac aucugggagu cugacuccaa ugaauuuucu guaauugcug      780

acccaagagg aaacacucua ggacggggaa cgacaauuac ccuugucuua aaagaagaag      840

caucugauua ccuugaauug gauacaauua aaaaucucgu caaaaaauau ucacaguuca      900

uaaacuuucc uauuuaugua uggagcagca agacugaaac uguugaggag cccauggagg      960

aagaagaagc agccaaagaa gagaaagaag aaucugauga ugaagcugca guagaggaag     1020

aagaagaaga aaagaaacca aagacuaaaa aaguugaaaa aacugucugg gacugggaac     1080

uuaugaauga uaucaaacca auauggcaga gaccaucaaa agaaguagaa gaagaugaau     1140

acaaagcuuu cuacaaauca uuuucaaagg aaagugauga ccccauggcu uauauucacu     1200

uuacugcuga aggggaaguu accuucaaau caauuuuauu uguacccaca ucugcuccac     1260

guggucuguu ugacgaauau ggaucuaaaa agagcgauua cauuaagcuc uaugugcgcc     1320

guguauucau cacagacgac uuccaugaua ugaugccuaa auaccucaau uuugucaagg     1380

guguggugga cucagaugau cuccccuuga auguuucccg cgagacucuu cagcaacaua     1440

aacugcuuaa ggugauuagg aagaagcuug uucguaaaac gcuggacaug aucaagaaga     1500

uugcugauga uaaauacaau gauacuuuuu ggaaagaauu ugguaccaac aucaagcuug     1560

gugugauuga agaccacucg aaucgaacac gucuugcuaa acuucuuagg uuccagucuu     1620

cucaucaucc aacugacauu acuagccuag accaguaugu ggaaagaaug aaggaaaaac     1680

aagacaaaau cuacuucaug gcugggucca gcagaaaaga ggcugaaucu ucuccauuug     1740

uugagcgacu ucugaaaaag ggcuaugaag uuauuuaccu cacagaaccu guggaugaau     1800

acuguauuca ggcccuuccc gaauuugaug ggaagagguu ccagaauguu gccaaggaag     1860

gagugaaguu cgaugaaagu gagaaaacua aggagagucg ugaagcaguu gagaaagaau     1920

uugagccucu gcugaauugg augaaagaua aagcccuuaa ggacaagauu gaaaaggcug     1980

uggugucuca gcgccugaca gaaucuccgu gugcuuuggu ggccagccag uacggauggu     2040

cuggcaacau ggagagaauc augaaagcac aagcguacca aacgggcaag gacaucucua     2100

caaauuacua ugcgagucag aagaaaacau uugaaauuaa ucccagacac ccgcugauca     2160

gagacaugcu ucgacgaauu aaggaagaug aagaugauaa aacaguuuug gaucuugcug     2220

ugguuuuguu ugaaacagca acgcuucggu caggguaucu uuuaccagac acuaaagcau     2280

auggagauag aauagaaaga augcuucgcc ucaguuugaa cauugacccu gaugcaaagg     2340

uggaagaaga gcccgaagaa gaaccugaag agacagcaga agacacaaca gaagacacag     2400

agcaagacga agaugaagaa auggaugugg gaacagauga agaagaagaa acagcaaagg     2460

aaucuacagc ugaaaaagau gaauuguaag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  6294
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (wt)

<400>  6294
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgcgcgagc ugcgggcgcu gcugcugugg ggccgccgcc      120

ugcggccuuu gcugcgggcg ccggcgcugg cggccgugcc gggaggaaaa ccaauucugu      180

guccucggag gaccacagcc caguugggcc ccaggcgaaa cccagccugg agcuugcagg      240

caggacgacu guucagcacg cagaccgccg aggacaagga ggaaccccug cacucgauua      300

ucagcagcac agagagcgug caggguucca cuuccaaaca ugaguuccag gccgagacaa      360

agaagcuuuu ggacauuguu gcccgguccc uguacucaga aaaagaggug uuuauacggg      420

agcugaucuc caaugccagc gaugccuugg aaaaacugcg ucacaaacug gugucugacg      480

gccaagcacu gccagaaaug gagauucacu ugcagaccaa ugccgagaaa ggcaccauca      540

ccauccagga uacugguauc gggaugacac aggaagagcu gguguccaac cuggggacga      600

uugccagauc ggggucaaag gccuuccugg augcucugca gaaccaggcu gaggccagca      660

gcaagaucau cggccaguuu ggaguggguu ucuacucagc uuucauggug gcugacagag      720

uggaggucua uucccgcucg gcagccccgg ggagccuggg uuaccagugg cuuucagaug      780

guucuggagu guuugaaauc gccgaagcuu cgggaguuag aaccgggaca aaaaucauca      840

uccaccugaa auccgacugc aaggaguuuu ccagcgaggc ccgggugcga gaugugguaa      900

cgaaguacag caacuucguc agcuuccccu uguacuugaa uggaaggcgg augaacaccu      960

ugcaggccau cuggaugaug gaccccaagg auguccguga guggcaacau gaggaguucu     1020

accgcuacgu cgcgcaggcu cacgacaagc cccgcuacac ccugcacuau aagacggacg     1080

caccgcucaa cauccgcagc aucuucuacg ugcccgacau gaaaccgucc auguuugaug     1140

ugagccggga gcugggcucc agcguugcac uguacagccg caaaguccuc auccagacca     1200

aggccacgga cauccugccc aaguggcugc gcuucauccg agguguggug gacagugagg     1260

acauuccccu gaaccucagc cgggagcugc ugcaggagag cgcacucauc aggaaacucc     1320

gggacguuuu acagcagagg cugaucaaau ucuucauuga ccagaguaaa aaagaugcug     1380

agaaguaugc aaaguuuuuu gaagauuacg gccuguucau gcgggagggc auugugaccg     1440

ccaccgagca ggaggucaag gaggacauag caaagcugcu gcgcuacgag uccucggcgc     1500

ugcccuccgg gcagcuaacc agccucucag aauacgccag ccgcaugcgg gccggcaccc     1560

gcaacaucua cuaccugugc gcccccaacc gucaccuggc agagcacuca cccuacuaug     1620

aggccaugaa gaagaaagac acagagguuc ucuucugcuu ugagcaguuu gaugagcuca     1680

cccugcugca ccuucgugag uuugacaaga agaagcugau cucuguggag acggacauag     1740

ucguggauca cuacaaggag gagaaguuug aggacagguc cccagccgcc gagugccuau     1800

cagagaagga gacggaggag cucauggccu ggaugagaaa ugugcugggg ucgcguguca     1860

ccaacgugaa ggugacccuc cgacuggaca cccacccugc cauggucacc gugcuggaga     1920

ugggggcugc ccgccacuuc cugcgcaugc agcagcuggc caagacccag gaggagcgcg     1980

cacagcuccu gcagcccacg cuggagauca accccaggca cgcgcucauc aagaagcuga     2040

aucagcugcg cgcaagcgag ccuggccugg cucagcugcu gguggaucag auauacgaga     2100

acgccaugau ugcugcugga cuuguugacg acccuagggc cauggugggc cgcuugaaug     2160

agcugcuugu caaggcccug gagcgacacu gaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  6295
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (wt)

<400>  6295
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaauca gcagucuucc aacccaauua uuuaagugcu      120

gcuuuuguga uuucuugaag gugaagaugc acaccauguc cuccucgcau cucuucuacc      180

uggcgcugug ccugcucacc uucaccagcu cugccacggc uggaccggag acgcucugcg      240

gggcugagcu gguggaugcu cuucaguucg uguguggaga caggggcuuu uauuucaaca      300

agcccacagg guauggcucc agcagucgga gggcgccuca gacaggcauc guggaugagu      360

gcugcuuccg gagcugugau cuaaggaggc uggagaugua uugcgcaccc cucaagccug      420

ccaagucagc ucgcucuguc cgugcccagc gccacaccga caugcccaag acccagaagg      480

aaguacauuu gaagaacgca aguagaggga gugcaggaaa caagaacuac aggauguagg      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  6296
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (wt)

<400>  6296
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaucccaa uggggaaguc gaugcuggug cuucucaccu      120

ucuuggccuu cgccucgugc ugcauugcug cuuaccgccc cagugagacc cugugcggcg      180

gggagcuggu ggacacccuc caguucgucu guggggaccg cggcuucuac uucagcaggc      240

ccgcaagccg ugugagccgu cgcagccgug gcaucguuga ggagugcugu uuccgcagcu      300

gugaccuggc ccuccuggag acguacugug cuacccccgc caaguccgag agggacgugu      360

cgaccccucc gaccgugcuu ccggacaacu uccccagaua ccccgugggc aaguucuucc      420

aauaugacac cuggaagcag uccacccagc gccugcgcag gggccugccu gcccuccugc      480

gugcccgccg gggucacgug cucgccaagg agcucgaggc guucagggag gccaaacguc      540

accguccccu gauugcucua cccacccaag accccgccca cgggggcgcc cccccagaga      600

uggccagcaa ucggaaguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  6297
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (wt)

<400>  6297
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccacaagcgc cuucggucca guugccuucu      120

cccuggggcu gcuccuggug uugccugcug ccuucccugc cccaguaccc ccaggagaag      180

auuccaaaga uguagccgcc ccacacagac agccacucac cucuucagaa cgaauugaca      240

aacaaauucg guacauccuc gacggcaucu cagcccugag aaaggagaca uguaacaaga      300

guaacaugug ugaaagcagc aaagaggcac uggcagaaaa caaccugaac cuuccaaaga      360

uggcugaaaa agauggaugc uuccaaucug gauucaauga ggagacuugc cuggugaaaa      420

ucaucacugg ucuuuuggag uuugagguau accuagagua ccuccagaac agauuugaga      480

guagugagga acaagccaga gcugugcaga ugaguacaaa aguccugauc caguuccugc      540

agaaaaaggc aaagaaucua gaugcaauaa ccaccccuga cccaaccaca aaugccagcc      600

ugcugacgaa gcugcaggca cagaaccagu ggcugcagga caugacaacu caucucauuc      660

ugcgcagcuu uaaggaguuc cugcagucca gccugagggc ucuucggcaa auguagggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  6298
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (wt)

<400>  6298
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccuugcuuu ggcugagagg auuucuguug gcaaguugcu      120

ggauuauagu gaggaguucc cccaccccag gauccgaggg gcacagcgcg gcccccgacu      180

guccguccug ugcgcuggcc gcccucccaa aggauguacc caacucucag ccagagaugg      240

uggaggccgu caagaagcac auuuuaaaca ugcugcacuu gaagaagaga cccgauguca      300

cccagccggu acccaaggcg gcgcuucuga acgcgaucag aaagcuucau gugggcaaag      360

ucggggagaa cggguaugug gagauagagg augacauugg aaggagggca gaaaugaaug      420

aacuuaugga gcagaccucg gagaucauca cguuugccga gucaggaaca gccaggaaga      480

cgcugcacuu cgagauuucc aaggaaggca gugaccuguc agugguggag cgugcagaag      540

ucuggcucuu ccuaaaaguc cccaaggcca acaggaccag gaccaaaguc accauccgcc      600

ucuuccagca gcagaagcac ccgcagggca gcuuggacac aggggaagag gccgaggaag      660

ugggcuuaaa gggggagagg agugaacugu ugcucucuga aaaaguagua gacgcucgga      720

agagcaccug gcaugucuuc ccugucucca gcagcaucca gcgguugcug gaccagggca      780

agagcucccu ggacguucgg auugccugug agcagugcca ggagaguggc gccagcuugg      840

uucuccuggg caagaagaag aagaaagaag aggaggggga agggaaaaag aagggcggag      900

gugaaggugg ggcaggagca gaugaggaaa aggagcaguc gcacagaccu uuccucaugc      960

ugcaggcccg gcagucugaa gaccacccuc aucgccggcg ucggcggggc uuggagugug     1020

auggcaaggu caacaucugc uguaagaaac aguucuuugu caguuucaag gacaucggcu     1080

ggaaugacug gaucauugcu cccucuggcu aucaugccaa cuacugcgag ggugagugcc     1140

cgagccauau agcaggcacg uccggguccu cacuguccuu ccacucaaca gucaucaacc     1200

acuaccgcau gcggggccau agccccuuug ccaaccucaa aucgugcugu gugcccacca     1260

agcugagacc cauguccaug uuguacuaug augaugguca aaacaucauc aaaaaggaca     1320

uucagaacau gaucguggag gagugugggu gcucauaggg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  6299
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (wt)

<400>  6299
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacgggcugc ccggucgggc gcugggggcc gccugccuuc      120

ugcugcuggc ggccggcugg cuggggccug aggccugggg cucacccacg cccccgccga      180

cgccugccgc gccgccgcca cccccgccac ccggaucccc ggguggcucg caggacaccu      240

guacgucgug cggcggcuuc cggcggccag aggagcucgg ccgaguggac ggcgacuucc      300

uggaggcggu gaagcggcac aucuugagcc gccugcagau gcggggccgg cccaacauca      360

cgcacgccgu gccuaaggcc gccaugguca cggcccugcg caagcugcac gcgggcaagg      420

ugcgcgagga cggccgcgug gagaucccgc accucgacgg ccacgccagc ccgggcgccg      480

acggccagga gcgcguuucc gaaaucauca gcuucgccga gacagauggc cucgccuccu      540

cccggguccg ccuauacuuc uucaucucca acgaaggcaa ccagaaccug uuuguggucc      600

aggccagccu guggcuuuac cugaaacucc ugcccuacgu ccuggagaag ggcagccggc      660

ggaaggugcg ggucaaagug uacuuccagg agcagggcca cggugacagg uggaacaugg      720

uggagaagag gguggaccuc aagcgcagcg gcuggcauac cuucccacuc acggaggcca      780

uccaggccuu guuugagcgg ggcgagcggc gacucaaccu agacgugcag ugugacagcu      840

gccaggagcu ggccguggug ccgguguucg uggacccagg cgaagagucg caccggcccu      900

uugugguggu gcaggcucgg cugggcgaca gcaggcaccg cauucgcaag cgaggccugg      960

agugcgaugg ccggaccaac cucuguugca ggcaacaguu cuucauugac uuccgccuca     1020

ucggcuggaa cgacuggauc auagcaccca ccggcuacua cgggaacuac ugugagggca     1080

gcugcccagc cuaccuggca gggguccccg gcucugccuc cuccuuccac acggcugugg     1140

ugaaccagua ccgcaugcgg ggucugaacc ccggcacggu gaacuccugc ugcauuccca     1200

ccaagcugag caccaugucc augcuguacu ucgaugauga guacaacauc gucaagcggg     1260

acgugcccaa caugauugug gaggagugcg gcugcgccug aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  6300
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (wt)

<400>  6300
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucucagag uccuucuguu aacagccuug accuuauguc      120

auggguucaa cuuggacacu gaaaacgcaa ugaccuucca agagaacgca aggggcuucg      180

ggcagagcgu gguccagcuu cagggaucca gggugguggu uggagccccc caggagauag      240

uggcugccaa ccaaaggggc agccucuacc agugcgacua cagcacaggc ucaugcgagc      300

ccauccgccu gcaggucccc guggaggccg ugaacauguc ccugggccug ucccuggcag      360

ccaccaccag ccccccucag cugcuggccu guggucccac cgugcaccag acuugcagug      420

agaacacgua ugugaaaggg cucugcuucc uguuuggauc caaccuacgg cagcagcccc      480

agaaguuccc agaggcccuc cgaggguguc cucaagagga uagugacauu gccuucuuga      540

uugauggcuc ugguagcauc aucccacaug acuuucggcg gaugaaggag uuugucucaa      600

cugugaugga gcaauuaaaa aaguccaaaa ccuuguucuc uuugaugcag uacucugaag      660

aauuccggau ucacuuuacc uucaaagagu uccagaacaa cccuaaccca agaucacugg      720

ugaagccaau aacgcagcug cuugggcgga cacacacggc cacgggcauc cgcaaagugg      780

uacgagagcu guuuaacauc accaacggag cccgaaagaa ugccuuuaag auccuaguug      840

ucaucacgga uggagaaaag uuuggcgauc ccuugggaua ugaggauguc aucccugagg      900

cagacagaga gggagucauu cgcuacguca uugggguggg agaugccuuc cgcagugaga      960

aaucccgcca agagcuuaau accaucgcau ccaagccgcc ucgugaucac guguuccagg     1020

ugaauaacuu ugaggcucug aagaccauuc agaaccagcu ucgggagaag aucuuugcga     1080

ucgaggguac ucagacagga aguagcagcu ccuuugagca ugagaugucu caggaaggcu     1140

ucagcgcugc caucaccucu aauggccccu ugcugagcac uguggggagc uaugacuggg     1200

cugguggagu cuuucuauau acaucaaagg agaaaagcac cuucaucaac augaccagag     1260

uggauucaga caugaaugau gcuuacuugg guuaugcugc cgccaucauc uuacggaacc     1320

gggugcaaag ccugguucug ggggcaccuc gauaucagca caucggccug guagcgaugu     1380

ucaggcagaa cacuggcaug ugggagucca acgcuaaugu caagggcacc cagaucggcg     1440

ccuacuucgg ggccucccuc ugcuccgugg acguggacag caacggcagc accgaccugg     1500

uccucaucgg ggccccccau uacuacgagc agacccgagg gggccaggug uccgugugcc     1560

ccuugcccag ggggagggcu cgguggcagu gugaugcugu ucucuacggg gagcagggcc     1620

aacccugggg ccgcuuuggg gcagcccuaa cagugcuggg ggacguaaau ggggacaagc     1680

ugacggacgu ggccauuggg gccccaggag aggaggacaa ccggggugcu guuuaccugu     1740

uucacggaac cucaggaucu ggcaucagcc ccucccauag ccagcggaua gcaggcucca     1800

agcucucucc caggcuccag uauuuugguc agucacugag ugggggccag gaccucacaa     1860

uggauggacu gguagaccug acuguaggag cccaggggca cgugcugcug cucagguccc     1920

agccaguacu gagagucaag gcaaucaugg aguucaaucc cagggaagug gcaaggaaug     1980

uauuugagug uaaugaucag guggugaaag gcaaggaagc cggagagguc agagucugcc     2040

uccaugucca gaagagcaca cgggaucggc uaagagaagg acagauccag aguguuguga     2100

cuuaugaccu ggcucuggac uccggccgcc cacauucccg cgccgucuuc aaugagacaa     2160

agaacagcac acgcagacag acacaggucu uggggcugac ccagacuugu gagacccuga     2220

aacuacaguu gccgaauugc aucgaggacc cagugagccc cauugugcug cgccugaacu     2280

ucucucuggu gggaacgcca uugucugcuu ucgggaaccu ccggccagug cuggcggagg     2340

augcucagag acucuucaca gccuuguuuc ccuuugagaa gaauuguggc aaugacaaca     2400

ucugccagga ugaccucagc aucaccuuca guuucaugag ccuggacugc cucguggugg     2460

gugggccccg ggaguucaac gugacaguga cugugagaaa ugauggugag gacuccuaca     2520

ggacacaggu caccuucuuc uucccgcuug accuguccua ccggaaggug uccacgcucc     2580

agaaccagcg cucacagcga uccuggcgcc uggccuguga gucugccucc uccaccgaag     2640

ugucuggggc cuugaagagc accagcugca gcauaaacca ccccaucuuc ccggaaaacu     2700

cagaggucac cuuuaauauc acguuugaug uagacucuaa ggcuucccuu ggaaacaaac     2760

ugcuccucaa ggccaaugug accagugaga acaacaugcc cagaaccaac aaaaccgaau     2820

uccaacugga gcugccggug aaauaugcug ucuacauggu ggucaccagc cauggggucu     2880

ccacuaaaua ucucaacuuc acggccucag agaauaccag ucgggucaug cagcaucaau     2940

aucaggucag caaccugggg cagaggagcc uccccaucag ccugguguuc uuggugcccg     3000

uccggcugaa ccagacuguc auaugggacc gcccccaggu caccuucucc gagaaccucu     3060

cgaguacgug ccacaccaag gagcgcuugc ccucucacuc cgacuuucug gcugagcuuc     3120

ggaaggcccc cguggugaac ugcuccaucg cugucugcca gagaauccag ugugacaucc     3180

cguucuuugg cauccaggaa gaauucaaug cuacccucaa aggcaaccuc ucguuugacu     3240

gguacaucaa gaccucgcau aaccaccucc ugaucgugag cacagcugag aucuuguuua     3300

acgauuccgu guucacccug cugccgggac agggggcguu ugugaggucc cagacggaga     3360

ccaaagugga gccguucgag guccccaacc cccugccgcu caucgugggc agcucugucg     3420

ggggacugcu gcuccuggcc cucaucaccg ccgcgcugua caagcucggc uucuucaagc     3480

ggcaauacaa ggacaugaug agugaagggg gucccccggg ggccgaaccc caguagggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  6301
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (wt)

<400>  6301
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucccuga agacgcuucc auuucugcuc uuacuccaug      120

ugcagauuuc caaggccuuu ccuguaucuu cuaaagagaa aaauacaaaa acuguucagg      180

acuaccugga aaaguucuac caauuaccaa gcaaccagua ucagucuaca aggaagaaug      240

gcacuaaugu gaucguugaa aagcuuaaag aaaugcagcg auuuuuuggg uugaauguga      300

cggggaagcc aaaugaggaa acucuggaca ugaugaaaaa gccucgcugu ggagugccug      360

acaguggugg uuuuauguua accccaggaa accccaagug ggaacgcacu aacuugaccu      420

acaggauucg aaacuauacc ccacagcugu cagaggcuga gguagaaaga gcuaucaagg      480

augccuuuga acucuggagu guugcaucac cucucaucuu caccaggauc ucacagggag      540

aggcagauau caacauugcu uuuuaccaaa gagaucacgg ugacaauucu ccauuugaug      600

gacccaaugg aauccuugcu caugccuuuc agccaggcca agguauugga ggagaugcuc      660

auuuugaugc cgaagaaaca uggaccaaca ccuccgcaaa uuacaacuug uuucuuguug      720

cugcucauga auuuggccau ucuuuggggc ucgcucacuc cucugacccu ggugccuuga      780

uguaucccaa cuaugcuuuc agggaaacca gcaacuacuc acucccucaa gaugacaucg      840

auggcauuca ggccaucuau ggacuuucaa gcaacccuau ccaaccuacu ggaccaagca      900

cacccaaacc cugugacccc aguuugacau uugaugcuau caccacacuc cguggagaaa      960

uacuuuucuu uaaagacagg uacuucugga gaaggcaucc ucagcuacaa agagucgaaa     1020

ugaauuuuau uucucuauuc uggccauccc uuccaacugg uauacaggcu gcuuaugaag     1080

auuuugacag agaccucauu uuccuauuua aaggcaacca auacugggcu cugaguggcu     1140

augauauucu gcaagguuau cccaaggaua uaucaaacua uggcuucccc agcagcgucc     1200

aagcaauuga cgcagcuguu uucuacagaa guaaaacaua cuucuuugua aaugaccaau     1260

ucuggagaua ugauaaccaa agacaauuca uggagccagg uuaucccaaa agcauaucag     1320

gugccuuucc aggaauagag aguaaaguug augcaguuuu ccagcaagaa cauuucuucc     1380

augucuucag uggaccaaga uauuacgcau uugaucuuau ugcucagaga guuaccagag     1440

uugcaagagg caauaaaugg cuuaacugua gauauggcug aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  6302
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (wt)

<400>  6302
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccucuggc agccccuggu ccuggugcuc cuggugcugg      120

gcugcugcuu ugcugccccc agacagcgcc aguccacccu ugugcucuuc ccuggagacc      180

ugagaaccaa ucucaccgac aggcagcugg cagaggaaua ccuguaccgc uaugguuaca      240

cucggguggc agagaugcgu ggagagucga aaucucuggg gccugcgcug cugcuucucc      300

agaagcaacu gucccugccc gagaccggug agcuggauag cgccacgcug aaggccaugc      360

gaaccccacg gugcgggguc ccagaccugg gcagauucca aaccuuugag ggcgaccuca      420

aguggcacca ccacaacauc accuauugga uccaaaacua cucggaagac uugccgcggg      480

cggugauuga cgacgccuuu gcccgcgccu ucgcacugug gagcgcggug acgccgcuca      540

ccuucacucg cguguacagc cgggacgcag acaucgucau ccaguuuggu gucgcggagc      600

acggagacgg guaucccuuc gacgggaagg acgggcuccu ggcacacgcc uuuccuccug      660

gccccggcau ucagggagac gcccauuucg acgaugacga guuguggucc cugggcaagg      720

gcgucguggu uccaacucgg uuuggaaacg cagauggcgc ggccugccac uuccccuuca      780

ucuucgaggg ccgcuccuac ucugccugca ccaccgacgg ucgcuccgac ggcuugcccu      840

ggugcaguac cacggccaac uacgacaccg acgaccgguu uggcuucugc cccagcgaga      900

gacucuacac ccaggacggc aaugcugaug ggaaacccug ccaguuucca uucaucuucc      960

aaggccaauc cuacuccgcc ugcaccacgg acggucgcuc cgacggcuac cgcuggugcg     1020

ccaccaccgc caacuacgac cgggacaagc ucuucggcuu cugcccgacc cgagcugacu     1080

cgacggugau ggggggcaac ucggcggggg agcugugcgu cuuccccuuc acuuuccugg     1140

guaaggagua cucgaccugu accagcgagg gccgcggaga ugggcgccuc uggugcgcua     1200

ccaccucgaa cuuugacagc gacaagaagu ggggcuucug cccggaccaa ggauacaguu     1260

uguuccucgu ggcggcgcau gaguucggcc acgcgcuggg cuuagaucau uccucagugc     1320

cggaggcgcu cauguacccu auguaccgcu ucacugaggg gccccccuug cauaaggacg     1380

acgugaaugg cauccggcac cucuaugguc cucgcccuga accugagcca cggccuccaa     1440

ccaccaccac accgcagccc acggcucccc cgacggucug ccccaccgga ccccccacug     1500

uccaccccuc agagcgcccc acagcuggcc ccacaggucc ccccucagcu ggccccacag     1560

guccccccac ugcuggcccu ucuacggcca cuacugugcc uuugaguccg guggacgaug     1620

ccugcaacgu gaacaucuuc gacgccaucg cggagauugg gaaccagcug uauuuguuca     1680

aggaugggaa guacuggcga uucucugagg gcagggggag ccggccgcag ggccccuucc     1740

uuaucgccga caaguggccc gcgcugcccc gcaagcugga cucggucuuu gaggagcggc     1800

ucuccaagaa gcuuuucuuc uucucugggc gccaggugug gguguacaca ggcgcgucgg     1860

ugcugggccc gaggcgucug gacaagcugg gccugggagc cgacguggcc caggugaccg     1920

gggcccuccg gaguggcagg gggaagaugc ugcuguucag cgggcggcgc cucuggaggu     1980

ucgacgugaa ggcgcagaug guggaucccc ggagcgccag cgagguggac cggauguucc     2040

ccggggugcc uuuggacacg cacgacgucu uccaguaccg agagaaagcc uauuucugcc     2100

aggaccgcuu cuacuggcgc gugaguuccc ggagugaguu gaaccaggug gaccaagugg     2160

gcuacgugac cuaugacauc cugcagugcc cugaggacua gggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  6303
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (wt)

<400>  6303
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauccagggg uccuggcugc cuuccucuuc uugagcugga      120

cucauugucg ggcccugccc cuucccagug guggugauga agaugauuug ucugaggaag      180

accuccaguu ugcagagcgc uaccugagau cauacuacca uccuacaaau cucgcgggaa      240

uccugaagga gaaugcagca agcuccauga cugagaggcu ccgagaaaug cagucuuucu      300

ucggcuuaga ggugacuggc aaacuugacg auaacaccuu agaugucaug aaaaagccaa      360

gaugcggggu uccugaugug ggugaauaca auguuuuccc ucgaacucuu aaauggucca      420

aaaugaauuu aaccuacaga auugugaauu acaccccuga uaugacucau ucugaagucg      480

aaaaggcauu caaaaaagcc uucaaaguuu gguccgaugu aacuccucug aauuuuacca      540

gacuucacga uggcauugcu gacaucauga ucucuuuugg aauuaaggag cauggcgacu      600

ucuacccauu ugaugggccc ucuggccugc uggcucaugc uuuuccuccu gggccaaauu      660

auggaggaga ugcccauuuu gaugaugaug aaaccuggac aaguaguucc aaaggcuaca      720

acuuguuucu uguugcugcg caugaguucg gccacuccuu aggucuugac cacuccaagg      780

acccuggagc acucauguuu ccuaucuaca ccuacaccgg caaaagccac uuuaugcuuc      840

cugaugacga uguacaaggg auccagucuc ucuauggucc aggagaugaa gaccccaacc      900

cuaaacaucc aaaaacgcca gacaaaugug acccuuccuu aucccuugau gccauuacca      960

gucuccgagg agaaacaaug aucuuuaaag acagauucuu cuggcgccug cauccucagc     1020

agguugaugc ggagcuguuu uuaacgaaau cauuuuggcc agaacuuccc aaccguauug     1080

augcugcaua ugagcacccu ucucaugacc ucaucuucau cuucagaggu agaaaauuuu     1140

gggcucuuaa ugguuaugac auucuggaag guuaucccaa aaaaauaucu gaacuggguc     1200

uuccaaaaga aguuaagaag auaagugcag cuguucacuu ugaggauaca ggcaagacuc     1260

uccuguucuc aggaaaccag gucuggagau augaugauac uaaccauauu auggauaaag     1320

acuauccgag acuaauagaa gaagacuucc caggaauugg ugauaaagua gaugcugucu     1380

augagaaaaa ugguuauauc uauuuuuuca acggacccau acaguuugaa uacagcaucu     1440

ggaguaaccg uauuguucgc gucaugccag caaauuccau uuuguggugu uaaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6304
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (wt)

<400>  6304
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacuccaa acaccacaga ggacuaugac acgaccacag      120

aguuugacua uggggaugca acuccgugcc agaaggugaa cgagagggcc uuuggggccc      180

aacugcugcc cccucuguac uccuugguau uugucauugg ccugguugga aacauccugg      240

ugguccuggu ccuugugcaa uacaagaggc uaaaaaacau gaccagcauc uaccuccuga      300

accuggccau uucugaccug cucuuccugu ucacgcuucc cuucuggauc gacuacaagu      360

ugaaggauga cuggguuuuu ggugaugcca uguguaagau ccucucuggg uuuuauuaca      420

caggcuugua cagcgagauc uuuuucauca uccugcugac gauugacagg uaccuggcca      480

ucguccacgc cguguuugcc uugcgggcac ggaccgucac uuuugguguc aucaccagca      540

ucaucauuug ggcccuggcc aucuuggcuu ccaugccagg cuuauacuuu uccaagaccc      600

aaugggaauu cacucaccac accugcagcc uucacuuucc ucacgaaagc cuacgagagu      660

ggaagcuguu ucaggcucug aaacugaacc ucuuugggcu gguauugccu uuguugguca      720

ugaucaucug cuacacaggg auuauaaaga uucugcuaag acgaccaaau gagaagaaau      780

ccaaagcugu ccguuugauu uuugucauca ugaucaucuu uuuucucuuu uggacccccu      840

acaauuugac uauacuuauu ucuguuuucc aagacuuccu guucacccau gagugugagc      900

agagcagaca uuuggaccug gcugugcaag ugacggaggu gaucgccuac acgcacugcu      960

gugucaaccc agugaucuac gccuucguug gugagagguu ccggaaguac cugcggcagu     1020

uguuccacag gcguguggcu gugcaccugg uuaaauggcu ccccuuccuc uccguggaca     1080

ggcuggagag ggucagcucc acaucucccu ccacagggga gcaugaacuc ucugcugggu     1140

ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  6305
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (wt)

<400>  6305
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aggaccuugg cuugccugcu gcuccucggc ugcggauacc      120

ucgcccaugu ucuggccgag gaagccgaga ucccccgcga ggugaucgag aggcuggccc      180

gcagucagau ccacagcauc cgggaccucc agcgacuccu ggagauagac uccguaggga      240

gugaggauuc uuuggacacc agccugagag cucacggggu ccaugccacu aagcaugugc      300

ccgagaagcg gccccugccc auucggagga agagaagcau cgaggaagcu guccccgcug      360

ucugcaagac caggacgguc auuuacgaga uuccucggag ucaggucgac cccacguccg      420

ccaacuuccu gaucuggccc ccgugcgugg aggugaaacg cugcaccggc ugcugcaaca      480

cgagcagugu caagugccag cccucccgcg uccaccaccg cagcgucaag guggccaagg      540

uggaauacgu caggaagaag ccaaaauuaa aagaagucca ggugagguua gaggagcauu      600

uggagugcgc cugcgcgacc acaagccuga auccggauua ucgggaagag gacacgggaa      660

ggccuaggga gucagguaaa aaacggaaaa gaaaaagguu aaaacccacc uaaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  6306
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (wt)

<400>  6306
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaucgcugcu gggcgcucuu ccugucucuc ugcugcuacc      120

ugcgucuggu cagcgccgag ggggacccca uucccgagga gcuuuaugag augcugagug      180

accacucgau ccgcuccuuu gaugaucucc aacgccugcu gcacggagac cccggagagg      240

aagauggggc cgaguuggac cugaacauga cccgcuccca cucuggaggc gagcuggaga      300

gcuuggcucg uggaagaagg agccuggguu cccugaccau ugcugagccg gccaugaucg      360

ccgagugcaa gacgcgcacc gagguguucg agaucucccg gcgccucaua gaccgcacca      420

acgccaacuu ccuggugugg ccgcccugug uggaggugca gcgcugcucc ggcugcugca      480

acaaccgcaa cgugcagugc cgccccaccc aggugcagcu gcgaccuguc caggugagaa      540

agaucgagau ugugcggaag aagccaaucu uuaagaaggc cacggugacg cuggaagacc      600

accuggcaug caagugugag acaguggcag cugcacggcc ugugacccga agcccggggg      660

guucccagga gcagcgagcc aaaacgcccc aaacucgggu gaccauucgg acggugcgag      720

uccgccggcc ccccaagggc aagcaccgga aauucaagca cacgcaugac aagacggcac      780

ugaaggagac ccuuggagcc uagggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  6307
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (wt)

<400>  6307
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccucuucg ggcuucuccu gcugacaucu gcccuggccg      120

gccagagaca ggggacucag gcggaaucca accugaguag uaaauuccag uuuuccagca      180

acaaggaaca gaacggagua caagauccuc agcaugagag aauuauuacu gugucuacua      240

auggaaguau ucacagccca agguuuccuc auacuuaucc aagaaauacg gucuugguau      300

ggagauuagu agcaguagag gaaaauguau ggauacaacu uacguuugau gaaagauuug      360

ggcuugaaga cccagaagau gacauaugca aguaugauuu uguagaaguu gaggaaccca      420

gugauggaac uauauuaggg cgcuggugug guucugguac uguaccagga aaacagauuu      480

cuaaaggaaa ucaaauuagg auaagauuug uaucugauga auauuuuccu ucugaaccag      540

gguucugcau ccacuacaac auugucaugc cacaauucac agaagcugug aguccuucag      600

ugcuaccccc uucagcuuug ccacuggacc ugcuuaauaa ugcuauaacu gccuuuagua      660

ccuuggaaga ccuuauucga uaucuugaac cagagagaug gcaguuggac uuagaagauc      720

uauauaggcc aacuuggcaa cuucuuggca aggcuuuugu uuuuggaaga aaauccagag      780

ugguggaucu gaaccuucua acagaggagg uaagauuaua cagcugcaca ccucguaacu      840

ucucaguguc cauaagggaa gaacuaaaga gaaccgauac cauuuucugg ccagguuguc      900

uccugguuaa acgcuguggu gggaacugug ccuguugucu ccacaauugc aaugaauguc      960

aauguguccc aagcaaaguu acuaaaaaau accacgaggu ccuucaguug agaccaaaga     1020

ccggugucag gggauugcac aaaucacuca ccgacguggc ccuggagcac caugaggagu     1080

gugacugugu gugcagaggg agcacaggag gauagggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  6308
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (wt)

<400>  6308
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccggcuca ucuuugucua cacucuaauc ugcgcaaacu      120

uuugcagcug ucgggacacu ucugcaaccc cgcagagcgc auccaucaaa gcuuugcgca      180

acgccaaccu caggcgagau gacuuguacc gaagagauga gaccauccag gugaaaggaa      240

acggcuacgu gcagaguccu agauucccga acagcuaccc caggaaccug cuccugacau      300

ggcggcuuca cucucaggag aauacacgga uacagcuagu guuugacaau caguuuggau      360

uagaggaagc agaaaaugau aucuguaggu augauuuugu ggaaguugaa gauauauccg      420

aaaccaguac cauuauuaga ggacgauggu guggacacaa ggaaguuccu ccaaggauaa      480

aaucaagaac gaaccaaauu aaaaucacau ucaaguccga ugacuacuuu guggcuaaac      540

cuggauucaa gauuuauuau ucuuugcugg aagauuucca acccgcagca gcuucagaga      600

ccaacuggga aucugucaca agcucuauuu cagggguauc cuauaacucu ccaucaguaa      660

cggaucccac ucugauugcg gaugcucugg acaaaaaaau ugcagaauuu gauacagugg      720

aagaucugcu caaguacuuc aauccagagu cauggcaaga agaucuugag aauauguauc      780

uggacacccc ucgguaucga ggcaggucau accaugaccg gaagucaaaa guugaccugg      840

auaggcucaa ugaugaugcc aagcguuaca guugcacucc caggaauuac ucggucaaua      900

uaagagaaga gcugaaguug gccaaugugg ucuucuuucc acguugccuc cucgugcagc      960

gcuguggagg aaauuguggc uguggaacug ucaacuggag guccugcaca ugcaauucag     1020

ggaaaaccgu gaaaaaguau caugagguau uacaguuuga gccuggccac aucaagagga     1080

gggguagagc uaagaccaug gcucuaguug acauccaguu ggaucaccau gaacgaugug     1140

auuguaucug cagcucaaga ccaccucgau aaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  6309
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (wt)

<400>  6309
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccaca gcaaguuucc cgccgccggg augagccgcc      120

cccuggacac cagccugcgc cucaagaccu ucagcuccaa gagcgaguac cagcuggugg      180

ugaacgcagu gcgcaagcug caggagagcg gcuucuacug gagcgcagug accggcggcg      240

aggcgaaccu gcugcucagu gccgagcccg ccggcaccuu ucugauccgc gacagcucgg      300

accagcgcca cuucuucacg cucagcguca agacccaguc ugggaccaag aaccugcgca      360

uccaguguga ggggggcagc uucucucugc agagcgaucc ccggagcacg cagcccgugc      420

cccgcuucga cugcgugcuc aagcuggugc accacuacau gccgcccccu ggagcccccu      480

ccuuccccuc gccaccuacu gaacccuccu ccgaggugcc cgagcagccg ucugcccagc      540

cacucccugg gagucccccc agaagagccu auuacaucua cuccgggggc gagaagaucc      600

cccugguguu gagccggccc cucuccucca acguggccac ucuucagcau cucugucgga      660

agaccgucaa cggccaccug gacuccuaug agaaagucac ccagcugccg gggcccauuc      720

gggaguuccu ggaccaguac gaugccccgc uuuaaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  6310
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (wt)

<400>  6310
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guccccucgg cuggacagcu cgcccuguuc gcucugggua      120

uuguguuggc ugcgugccag gccuuggaga acagcacguc cccgcugagu gcagacccgc      180

ccguggcugc agcaguggug ucccauuuua augacugccc agauucccac acucaguucu      240

gcuuccaugg aaccugcagg uuuuuggugc aggaggacaa gccagcaugu gucugccauu      300

cuggguacgu uggugcacgc ugugagcaug cggaccuccu ggccguggug gcugccagcc      360

agaagaagca ggccaucacc gccuuggugg uggucuccau cguggcccug gcuguccuua      420

ucaucacaug ugugcugaua cacugcugcc agguccgaaa acacugugag uggugccggg      480

cccucaucug ccggcacgag aagcccagcg cccuccugaa gggaagaacc gcuugcugcc      540

acucagaaac aguggucuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  6311
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (wt)

<400>  6311
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccgcccuccg ggcugcggcu gcugccgcug cugcuaccgc      120

ugcuguggcu acuggugcug acgccuggcc ggccggccgc gggacuaucc accugcaaga      180

cuaucgacau ggagcuggug aagcggaagc gcaucgaggc cauccgcggc cagauccugu      240

ccaagcugcg gcucgccagc cccccgagcc agggggaggu gccgcccggc ccgcugcccg      300

aggccgugcu cgcccuguac aacagcaccc gcgaccgggu ggccggggag agugcagaac      360

cggagcccga gccugaggcc gacuacuacg ccaaggaggu cacccgcgug cuaauggugg      420

aaacccacaa cgaaaucuau gacaaguuca agcagaguac acacagcaua uauauguucu      480

ucaacacauc agagcuccga gaagcgguac cugaacccgu guugcucucc cgggcagagc      540

ugcgucugcu gaggcucaag uuaaaagugg agcagcacgu ggagcuguac cagaaauaca      600

gcaacaauuc cuggcgauac cucagcaacc ggcugcuggc acccagcgac ucgccagagu      660

gguuaucuuu ugaugucacc ggaguugugc ggcagugguu gagccgugga ggggaaauug      720

agggcuuucg ccuuagcgcc cacugcuccu gugacagcag ggauaacaca cugcaagugg      780

acaucaacgg guucacuacc ggccgccgag gugaccuggc caccauucau ggcaugaacc      840

ggccuuuccu gcuucucaug gccaccccgc uggagagggc ccagcaucug caaagcuccc      900

ggcaccgccg agcccuggac accaacuauu gcuucagcuc cacggagaag aacugcugcg      960

ugcggcagcu guacauugac uuccgcaagg accucggcug gaaguggauc cacgagccca     1020

agggcuacca ugccaacuuc ugccucgggc ccugccccua cauuuggagc cuggacacgc     1080

aguacagcaa gguccuggcc cuguacaacc agcauaaccc gggcgccucg gcggcgccgu     1140

gcugcgugcc gcaggcgcug gagccgcugc ccaucgugua cuacgugggc cgcaagccca     1200

agguggagca gcuguccaac augaucgugc gcuccugcaa gugcagcuga ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  6312
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (wt)

<400>  6312
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugug ugcugagcgc uuuucugauc cugcaucugg      120

ucacggucgc gcucagccug ucuaccugca gcacacucga uauggaccag uucaugcgca      180

agaggaucga ggcgauccgc gggcagaucc ugagcaagcu gaagcucacc agucccccag      240

aagacuaucc ugagcccgag gaaguccccc cggaggugau uuccaucuac aacagcacca      300

gggacuugcu ccaggagaag gcgagccgga gggcggccgc cugcgagcgc gagaggagcg      360

acgaagagua cuacgccaag gagguuuaca aaauagacau gccgcccuuc uuccccuccg      420

aaaaugccau cccgcccacu uucuacagac ccuacuucag aauuguucga uuugacgucu      480

cagcaaugga gaagaaugcu uccaauuugg ugaaagcaga guucagaguc uuucguuugc      540

agaacccaaa agccagagug ccugaacaac ggauugagcu auaucagauu cucaagucca      600

aagauuuaac aucuccaacc cagcgcuaca ucgacagcaa aguugugaaa acaagagcag      660

aaggcgaaug gcucuccuuc gauguaacug augcuguuca ugaauggcuu caccauaaag      720

acaggaaccu gggauuuaaa auaagcuuac acugucccug cugcacuuuu guaccaucua      780

auaauuacau caucccaaau aaaagugaag aacuagaagc aagauuugca gguauugaug      840

gcaccuccac auauaccagu ggugaucaga aaacuauaaa guccacuagg aaaaaaaaca      900

gugggaagac cccacaucuc cugcuaaugu uauugcccuc cuacagacuu gagucacaac      960

agaccaaccg gcggaagaag cgugcuuugg augcggccua uugcuuuaga aaugugcagg     1020

auaauugcug ccuacgucca cuuuacauug auuucaagag ggaucuaggg uggaaaugga     1080

uacacgaacc caaaggguac aaugccaacu ucugugcugg agcaugcccg uauuuaugga     1140

guucagacac ucagcacagc aggguccuga gcuuauauaa uaccauaaau ccagaagcau     1200

cugcuucucc uugcugcgug ucccaagauu uagaaccucu aaccauucuc uacuacauug     1260

gcaaaacacc caagauugaa cagcuuucua auaugauugu aaagucuugc aaaugcagcu     1320

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  6313
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (wt)

<400>  6313
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacu ugcaaagggc ucuggugguc cuggcccugc      120

ugaacuuugc cacggucagc cucucucugu ccacuugcac caccuuggac uucggccaca      180

ucaagaagaa gaggguggaa gccauuaggg gacagaucuu gagcaagcuc aggcucacca      240

gccccccuga gccaacggug augacccacg uccccuauca gguccuggcc cuuuacaaca      300

gcacccggga gcugcuggag gagaugcaug gggagaggga ggaaggcugc acccaggaaa      360

acaccgaguc ggaauacuau gccaaagaaa uccauaaauu cgacaugauc caggggcugg      420

cggagcacaa cgaacuggcu gucugcccua aaggaauuac cuccaagguu uuccgcuuca      480

auguguccuc aguggagaaa aauagaacca accuauuccg agcagaauuc cgggucuugc      540

gggugcccaa ccccagcucu aagcggaaug agcagaggau cgagcucuuc cagauccuuc      600

ggccagauga gcacauugcc aaacagcgcu auaucggugg caagaaucug cccacacggg      660

gcacugccga guggcugucc uuugauguca cugacacugu gcgugagugg cuguugagaa      720

gagaguccaa cuuaggucua gaaaucagca uucacugucc augucacacc uuucagccca      780

auggagauau ccuggaaaac auucacgagg ugauggaaau caaauucaaa ggcguggaca      840

augaggauga ccauggccgu ggagaucugg ggcgccucaa gaagcagaag gaucaccaca      900

acccucaucu aauccucaug augauucccc cacaccggcu cgacaacccg ggccaggggg      960

gucagaggaa gaagcgggcu uuggacacca auuacugcuu ccgcaacuug gaggagaacu     1020

gcugugugcg cccccucuac auugacuucc gacaggaucu gggcuggaag uggguccaug     1080

aaccuaaggg cuacuaugcc aacuucugcu caggcccuug cccauaccuc cgcagugcag     1140

acacaaccca cagcacggug cugggacugu acaacacucu gaacccugaa gcaucugccu     1200

cgccuugcug cgugccccag gaccuggagc cccugaccau ccuguacuau guugggagga     1260

cccccaaagu ggagcagcuc uccaacaugg uggugaaguc uuguaaaugu agcugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6314
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (wt)

<400>  6314
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgcccgucg ccgucugggc cgcgcuggcc gucggacugg      120

agcucugggc ugcggcgcac gccuugcccg cccagguggc auuuacaccc uacgccccgg      180

agcccgggag cacaugccgg cucagagaau acuaugacca gacagcucag augugcugca      240

gcaaaugcuc gccgggccaa caugcaaaag ucuucuguac caagaccucg gacaccgugu      300

gugacuccug ugaggacagc acauacaccc agcucuggaa cuggguuccc gagugcuuga      360

gcuguggcuc ccgcuguagc ucugaccagg uggaaacuca agccugcacu cgggaacaga      420

accgcaucug caccugcagg cccggcuggu acugcgcgcu gagcaagcag gaggggugcc      480

ggcugugcgc gccgcugcgc aagugccgcc cgggcuucgg cguggccaga ccaggaacug      540

aaacaucaga cguggugugc aagcccugug ccccggggac guucuccaac acgacuucau      600

ccacggauau uugcaggccc caccagaucu guaacguggu ggccaucccu gggaaugcaa      660

gcauggaugc agucugcacg uccacguccc ccacccggag uauggcccca ggggcaguac      720

acuuacccca gccagugucc acacgauccc aacacacgca gccaacucca gaacccagca      780

cugcuccaag caccuccuuc cugcucccaa ugggccccag ccccccagcu gaagggagca      840

cuggcgacuu cgcucuucca guuggacuga uugugggugu gacagccuug ggucuacuaa      900

uaauaggagu ggugaacugu gucaucauga cccaggugaa aaagaagccc uugugccugc      960

agagagaagc caaggugccu cacuugccug ccgauaaggc ccgggguaca cagggccccg     1020

agcagcagca ccugcugauc acagcgccga gcuccagcag cagcucccug gagagcucgg     1080

ccagugcguu ggacagaagg gcgcccacuc ggaaccagcc acaggcacca ggcguggagg     1140

ccaguggggc cggggaggcc cgggccagca ccgggagcuc agauucuucc ccugguggcc     1200

augggaccca ggucaauguc accugcaucg ugaacgucug uagcagcucu gaccacagcu     1260

cacagugcuc cucccaagcc agcuccacaa ugggagacac agauuccagc cccucggagu     1320

ccccgaagga cgagcagguc cccuucucca aggaggaaug ugccuuucgg ucacagcugg     1380

agacgccaga gacccugcug gggagcaccg aagagaagcc ccugccccuu ggagugccug     1440

augcugggau gaagcccagu uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  6315
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (wt)

<400>  6315
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggucauga ggcuguuccc uugcuuccug cagcuccugg      120

ccgggcuggc gcugccugcu gugccccccc agcagugggc cuugucugcu gggaacggcu      180

cgucagaggu ggaaguggua cccuuccagg aagugugggg ccgcagcuac ugccgggcgc      240

uggagaggcu gguggacguc guguccgagu accccagcga gguggagcac auguucagcc      300

cauccugugu cucccugcug cgcugcaccg gcugcugcgg cgaugagaau cugcacugug      360

ugccggugga gacggccaau gucaccaugc agcuccuaaa gauccguucu ggggaccggc      420

ccuccuacgu ggagcugacg uucucucagc acguucgcug cgaaugccgg ccucugcggg      480

agaagaugaa gccggaaagg aggagaccca agggcagggg gaagaggagg agagagaagc      540

agagacccac agacugccac cugugcggcg augcuguucc ccggagguaa ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  6316
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (wt)

<400>  6316
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acggacagac agacagacac cgcccccagc cccagcuacc      120

accuccuccc cggccggcgg cggacagugg acgcggcggc gagccgcggg caggggccgg      180

agcccgcgcc cggaggcggg guggaggggg ucggggcucg cggcgucgca cugaaacuuu      240

ucguccaacu ucugggcugu ucucgcuucg gaggagccgu gguccgcgcg ggggaagccg      300

agccgagcgg agccgcgaga agugcuagcu cgggccggga ggagccgcag ccggaggagg      360

gggaggagga agaagagaag gaagaggaga gggggccgca guggcgacuc ggcgcucgga      420

agccgggcuc auggacgggu gaggcggcgg ugugcgcaga cagugcucca gccgcgcgcg      480

cuccccaggc ccuggcccgg gccucgggcc ggggaggaag aguagcucgc cgaggcgccg      540

aggagagcgg gccgccccac agcccgagcc ggagagggag cgcgagccgc gccggccccg      600

gucgggccuc cgaaaccaug aacuuucugc ugucuugggu gcauuggagc cuugccuugc      660

ugcucuaccu ccaccaugcc aagugguccc aggcugcacc cauggcagaa ggaggagggc      720

agaaucauca cgaaguggug aaguucaugg augucuauca gcgcagcuac ugccauccaa      780

ucgagacccu gguggacauc uuccaggagu acccugauga gaucgaguac aucuucaagc      840

cauccugugu gccccugaug cgaugcgggg gcugcugcaa ugacgagggc cuggagugug      900

ugcccacuga ggaguccaac aucaccaugc agauuaugcg gaucaaaccu caccaaggcc      960

agcacauagg agagaugagc uuccuacagc acaacaaaug ugaaugcaga ccaaagaaag     1020

auagagcaag acaagaaaaa aaaucaguuc gaggaaaggg aaaggggcaa aaacgaaagc     1080

gcaagaaauc ccgguauaag uccuggagcg uguacguugg ugcccgcugc ugucuaaugc     1140

ccuggagccu cccuggcccc caucccugug ggccuugcuc agagcggaga aagcauuugu     1200

uuguacaaga uccgcagacg uguaaauguu ccugcaaaaa cacagacucg cguugcaagg     1260

cgaggcagcu ugaguuaaac gaacguacuu gcagauguga caagccgagg cggugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6317
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (wt)

<400>  6317
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuucugc ugucuugggu gcauuggagc cuugccuugc      120

ugcucuaccu ccaccaugcc aagugguccc aggcugcacc cauggcagaa ggaggagggc      180

agaaucauca cgaaguggug aaguucaugg augucuauca gcgcagcuac ugccauccaa      240

ucgagacccu gguggacauc uuccaggagu acccugauga gaucgaguac aucuucaagc      300

cauccugugu gccccugaug cgaugcgggg gcugcugcaa ugacgagggc cuggagugug      360

ugcccacuga ggaguccaac aucaccaugc agauuaugcg gaucaaaccu caccaaggcc      420

agcacauagg agagaugagc uuccuacagc acaacaaaug ugaaugcaga ccaaagaaag      480

auagagcaag acaagaaaaa aaaucaguuc gaggaaaggg aaaggggcaa aaacgaaagc      540

gcaagaaauc ccgguauaag uccuggagcg uguacguugg ugcccgcugc ugucuaaugc      600

ccuggagccu cccuggcccc caucccugug ggccuugcuc agagcggaga aagcauuugu      660

uuguacaaga uccgcagacg uguaaauguu ccugcaaaaa cacagacucg cguugcaagg      720

cgaggcagcu ugaguuaaac gaacguacuu gcagauguga caagccgagg cggugaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  6318
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (wt)

<400>  6318
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcccucugc uccgccgccu gcugcucgcc gcacuccugc      120

agcuggcccc cgcccaggcc ccugucuccc agccugaugc cccuggccac cagaggaaag      180

uggugucaug gauagaugug uauacucgcg cuaccugcca gccccgggag gugguggugc      240

ccuugacugu ggagcucaug ggcaccgugg ccaaacagcu ggugcccagc ugcgugacug      300

ugcagcgcug ugguggcugc ugcccugacg auggccugga gugugugccc acugggcagc      360

accaaguccg gaugcagauc cucaugaucc gguacccgag cagucagcug ggggagaugu      420

cccuggaaga acacagccag ugugaaugca gaccuaaaaa aaaggacagu gcugugaagc      480

cagacagggc ugccacuccc caccaccguc cccagccccg uucuguuccg ggcugggacu      540

cugcccccgg agcacccucc ccagcugaca ucacccaucc cacuccagcc ccaggccccu      600

cugcccacgc ugcacccagc accaccagcg cccugacccc cggaccugcc gcugccgcug      660

ccgacgccgc agcuuccucc guugccaagg gcggggcuua gggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  6319
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (wt)

<400>  6319
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuugcugg gcuucuucuc uguggcgugu ucucugcucg      120

ccgcugcgcu gcucccgggu ccucgcgagg cgcccgccgc cgccgccgcc uucgaguccg      180

gacucgaccu cucggacgcg gagcccgacg cgggcgaggc cacggcuuau gcaagcaaag      240

aucuggagga gcaguuacgg ucugugucca guguagauga acucaugacu guacucuacc      300

cagaauauug gaaaauguac aagugucagc uaaggaaagg aggcuggcaa cauaacagag      360

aacaggccaa ccucaacuca aggacagaag agacuauaaa auuugcugca gcacauuaua      420

auacagagau cuugaaaagu auugauaaug aguggagaaa gacucaaugc augccacggg      480

agguguguau agaugugggg aaggaguuug gagucgcgac aaacaccuuc uuuaaaccuc      540

cauguguguc cgucuacaga uguggggguu gcugcaauag ugaggggcug cagugcauga      600

acaccagcac gagcuaccuc agcaagacgu uauuugaaau uacagugccu cucucucaag      660

gccccaaacc aguaacaauc aguuuugcca aucacacuuc cugccgaugc augucuaaac      720

uggauguuua cagacaaguu cauuccauua uuagacguuc ccugccagca acacuaccac      780

agugucaggc agcgaacaag accugcccca ccaauuacau guggaauaau cacaucugca      840

gaugccuggc ucaggaagau uuuauguuuu ccucggaugc uggagaugac ucaacagaug      900

gauuccauga caucugugga ccaaacaagg agcuggauga agagaccugu cagugugucu      960

gcagagcggg gcuucggccu gccagcugug gaccccacaa agaacuagac agaaacucau     1020

gccagugugu cuguaaaaac aaacucuucc ccagccaaug uggggccaac cgagaauuug     1080

augaaaacac augccagugu guauguaaaa gaaccugccc cagaaaucaa ccccuaaauc     1140

cuggaaaaug ugccugugaa uguacagaaa guccacagaa augcuuguua aaaggaaaga     1200

aguuccacca ccaaacaugc agcuguuaca gacggccaug uacgaaccgc cagaaggcuu     1260

gugagccagg auuuucauau agugaagaag ugugucguug ugucccuuca uauuggaaaa     1320

gaccacaaau gagcuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  6320
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (wt)

<400>  6320
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagagu ggguaguggu gaauguuuuc augauguugu      120

acguccagcu ggugcagggc uccaguaaug aacauggacc agugaagcga ucaucucagu      180

ccacauugga acgaucugaa cagcagauca gggcugcuuc uaguuuggag gaacuacuuc      240

gaauuacuca cucugaggac uggaagcugu ggagaugcag gcugaggcuc aaaaguuuua      300

ccaguaugga cucucgcuca gcaucccauc gguccacuag guuugcggca acuuucuaug      360

acauugaaac acuaaaaguu auagaugaag aauggcaaag aacucagugc agcccuagag      420

aaacgugcgu ggagguggcc agugagcugg ggaagaguac caacacauuc uucaagcccc      480

cuugugugaa cguguuccga ugugguggcu guugcaauga agagagccuu aucuguauga      540

acaccagcac cucguacauu uccaaacagc ucuuugagau aucagugccu uugacaucag      600

uaccugaauu agugccuguu aaaguugcca aucauacagg uuguaagugc uugccaacag      660

ccccccgcca uccauacuca auuaucagaa gauccaucca gaucccugaa gaagaucgcu      720

guucccauuc caagaaacuc uguccuauug acaugcuaug ggauagcaac aaauguaaau      780

guguuuugca ggaggaaaau ccacuugcug gaacagaaga ccacucucau cuccaggaac      840

cagcucucug ugggccacac augauguuug acgaagaucg uugcgagugu gucuguaaaa      900

caccaugucc caaagaucua auccagcacc ccaaaaacug caguugcuuu gagugcaaag      960

aaagucugga gaccugcugc cagaagcaca agcuauuuca cccagacacc ugcagcugug     1020

aggacagaug ccccuuucau accagaccau gugcaagugg caaaacagca ugugcaaagc     1080

auugccgcuu uccaaaggag aaaagggcug cccaggggcc ccacagccga aagaauccuu     1140

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  6321
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt1)

<400>  6321
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgacg agaccggcuu cgagcacucc gggcuguggg      120

ugagcguccu cgccggccug cugcucgggg ccugccaggc ccaccccauc ccggacucca      180

gcccccugcu gcaguucggc ggccaggugc gccagcggua ccucuacacc gacgacgccc      240

agcagacgga ggcccaccug gagauccgcg aggacgggac cgugggcggg gccgccgacc      300

agucccccga gagccugcuc cagcugaagg cgcugaagcc cggcgucauc cagauccucg      360

gggugaagac cucccgguuc cugugccagc gcccggacgg cgcccuguac gggagccucc      420

acuucgaccc cgaggccugc uccuuccggg agcugcugcu cgaggacggc uacaacgugu      480

accagagcga ggcccacggc cugccccugc accuccccgg gaacaagucc ccgcaccgcg      540

accccgcgcc ccggggcccc gcccgcuucc ugccgcugcc cgggcucccg cccgcccugc      600

ccgagccgcc cggcauccug gcgccccagc cgcccgacgu cggcagcucc gacccccuca      660

gcaugguggg gcccucccag ggccggagcc ccuccuacgc cagcugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  6322
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt1)

<400>  6322
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuucc cgccccugcu ccugcugcuc uucuggggcg      120

uggucuccca cagcuucccc gccacccugg agacccagga gcaggacgug gaccuggugc      180

agaaguaccu cgagaaguac uacaaccuga agaacgacgg gcgccagguc gagaagcggc      240

gcaacuccgg ccccguggug gagaagcuga agcagaugca ggaguucuuc gggcucaagg      300

ucacgggcaa gcccgacgcc gagacccuga aggugaugaa gcagccgcgg ugcggggugc      360

ccgacgucgc gcaguucgug cugaccgagg gcaacccccg cugggagcag acccaccuca      420

cguaccggau cgagaacuac acccccgacc ugccgcgcgc cgacguggac cacgccaucg      480

agaaggccuu ccagcugugg agcaacguca ccccgcucac cuucacgaag guguccgagg      540

gccaggccga caucaugauc agcuucgugc ggggcgacca ccgcgacaac ucccccuucg      600

acgggcccgg gggcaaccug gcgcacgccu uccagccggg gcccggcauc ggcggggacg      660

cccacuucga cgaggacgag cgguggacca acaacuuccg cgaguacaac cugcaccggg      720

ucgccgcgca cgagcucggc cacagccugg ggcuguccca cagcaccgac aucggcgccc      780

ucauguaccc cuccuacacc uucagcggcg acgugcagcu ggcccaggac gacaucgacg      840

ggauccaggc caucuacggc cgcucccaga accccgugca gccgaucggg ccccagacgc      900

ccaaggccug cgacagcaag cugaccuucg acgcgaucac caccauccgg ggcgagguca      960

uguucuucaa ggaccgcuuc uacaugcgga cgaaccccuu cuacccggag guggagcuca     1020

acuucaucuc cguguucugg ccccagcugc ccaacgggcu ggaggccgcc uacgaguucg     1080

ccgaccgcga cgagguccgg uucuucaagg gcaacaagua cugggccgug cagggccaga     1140

acgugcucca cggguacccc aaggacaucu acagcuccuu cggcuucccg cgcaccguca     1200

agcacaucga cgcggcccug agcgaggaga acaccgggaa gaccuacuuc uucguggcca     1260

acaaguacug gcgguacgac gaguacaagc gcuccaugga ccccggcuac cccaagauga     1320

ucgcccacga cuuccccggg aucggccaca aggucgacgc cguguucaug aaggacggcu     1380

ucuucuacuu cuuccacggg acgcggcagu acaaguucga cccgaagacc aagcgcaucc     1440

ugacccucca gaaggcgaac agcugguuca acugccgcaa gaacugagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  6323
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt1) 
       R6148/R6221

<400>  6323
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuucc cgccccugcu ccugcugcuc uucuggggcg      120

uggucuccca cagcuucgug cugaccgagg gcaacccccg cugggagcag acccaccuca      180

cguaccggau cgagaacuac acccccgacc ugccgcgcgc cgacguggac cacgccaucg      240

agaaggccuu ccagcugugg agcaacguca ccccgcucac cuucacgaag guguccgagg      300

gccaggccga caucaugauc agcuucgugc ggggcgacca ccgcgacaac ucccccuucg      360

acgggcccgg gggcaaccug gcgcacgccu uccagccggg gcccggcauc ggcggggacg      420

cccacuucga cgaggacgag cgguggacca acaacuuccg cgaguacaac cugcaccggg      480

ucgccgcgca cgagcucggc cacagccugg ggcuguccca cagcaccgac aucggcgccc      540

ucauguaccc cuccuacacc uucagcggcg acgugcagcu ggcccaggac gacaucgacg      600

ggauccaggc caucuacggc cgcucccaga accccgugca gccgaucggg ccccagacgc      660

ccaaggccug cgacagcaag cugaccuucg acgcgaucac caccauccgg ggcgagguca      720

uguucuucaa ggaccgcuuc uacaugcgga cgaaccccuu cuacccggag guggagcuca      780

acuucaucuc cguguucugg ccccagcugc ccaacgggcu ggaggccgcc uacgaguucg      840

ccgaccgcga cgagguccgg uucuucaagg gcaacaagua cugggccgug cagggccaga      900

acgugcucca cggguacccc aaggacaucu acagcuccuu cggcuucccg cgcaccguca      960

agcacaucga cgcggcccug agcgaggaga acaccgggaa gaccuacuuc uucguggcca     1020

acaaguacug gcgguacgac gaguacaagc gcuccaugga ccccggcuac cccaagauga     1080

ucgcccacga cuuccccggg aucggccaca aggucgacgc cguguucaug aaggacggcu     1140

ucuucuacuu cuuccacggg acgcggcagu acaaguucga cccgaagacc aagcgcaucc     1200

ugacccucca gaaggcgaac agcugguuca acugccgcaa gaacugagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  6324
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt1)

<400>  6324
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaagaaca uccugaagau ccucauggac agcuacucca      120

aggagagcaa gauccagacc gugcgccggg ucaccuccgu gagccugcug gccguguacc      180

ucacgaugaa caccuccagc cugguccugg ccaagcccau cgagaacacc aacgacaccu      240

ccaucaagaa cguggagaag cuccgcaacg cgcccaacga ggagaacagc aagaaggugg      300

aggacuccaa gaacgacaag gucgagcacg ugaagaacau cgaggaggcc aagguggagc      360

aggucgcccc cgaggugaag agcaagucca cgcugcggag cgccuccauc gccaacacca      420

acagcgagaa guacgacuuc gaguaccuga acggccucuc cuacaccgag cugaccaacc      480

ugaucaagaa caucaagugg aaccagauca acgggcucuu caacuacagc acgggcuccc      540

agaaguucuu cggggacaag aaccgcgugc aggcgaucau caacgcccug caggagagcg      600

gccggaccua caccgccaac gacaugaagg ggaucgagac cuucacggag guccugcgcg      660

ccggcuucua ccucggcuac uacaacgacg ggcuguccua ccugaacgac cggaacuucc      720

aggacaagug cauccccgcg augaucgcca uccagaagaa ccccaacuuc aagcucggca      780

ccgccgugca ggacgaggug aucaccagcc uggggaagcu gaucggcaac gccagcgcca      840

acgcggaggu cgugaacaac ugcgugccgg uccucaagca guuccgcgag aaccugaacc      900

aguacgcccc cgacuacgug aaggggaccg ccgugaacga gcugaucaag ggcaucgagu      960

ucgacuucuc cggcgccgcc uacgagaagg acgucaagac gaugcccugg uacgggaaga     1020

ucgaccccuu caucaacgag cucaaggcgc ugggccugua cgggaacauc accagcgcca     1080

ccgagugggc cuccgacgug ggcaucuacu accucagcaa guucggccug uacuccacca     1140

accggaacga caucgugcag agccuggaga aggccgucga cauguacaag uacgggaaga     1200

ucgccuucgu ggcgauggag cgcaucacgu gggacuacga cggcaucggg uccaacggca     1260

agaaggucga ccacgacaag uuccucgacg acgccgagaa gcacuaccug ccgaagaccu     1320

acaccuucga caacgggacc uucaucaucc gggccggcga caaggugagc gaggagaaga     1380

ucaagcgccu guacugggcc ucccgggagg ugaagagcca guuccaccgc gucgugggca     1440

acgacaaggc ccucgaggug gggaacgcgg acgacguccu gacgaugaag aucuucaacu     1500

cccccgagga guacaaguuc aacaccaaca ucaacggcgu gagcaccgac aacgggggcc     1560

uguacaucga gccgcggggg accuucuaca cguacgagcg caccccgcag caguccaucu     1620

ucagccucga ggagcuguuc cggcacgagu acacccacua ccugcaggcc cgcuaccucg     1680

uggacggccu guggggccag gggccguucu acgagaagaa ccggcugacc ugguucgacg     1740

agggcacggc cgaguucuuc gccgggucca cccgcaccag cggcguccuc ccccggaagu     1800

ccauccuggg guaccuggcg aaggacaagg uggaccaccg cuacagccuc aagaagaccc     1860

ugaacuccgg cuacgacgac agcgacugga uguucuacaa cuacggcuuc gccguggccc     1920

acuaccugua cgagaaggac augcccacgu ucaucaagau gaacaaggcc auccugaaca     1980

ccgacgucaa gagcuacgac gagaucauca agaagcucuc cgacgacgcc aacaagaaca     2040

ccgaguacca gaaccacauc caggagcugg cggacaagua ccagggggcc ggcauccccc     2100

uggugagcga cgacuaccuc aaggaccacg gguacaagaa ggccuccgag guguacagcg     2160

agaucuccaa ggccgccagc cugaccaaca ccuccgucac ggcggagaag agccaguacu     2220

ucaacaccuu cacccugcgc ggcaccuaca cgggcgagac cuccaagggg gaguucaagg     2280

acugggacga gaugagcaag aagcucgacg gcacccugga gucccuggcc aagaacagcu     2340

gguccgggua caagacccuc acggccuacu ucaccaacua ccgggugacc agcgacaaca     2400

aggugcagua cgacgucgug uuccacggcg ugcugaccga caacgccgac aucuccaaca     2460

acaaggcccc gaucgcgaag gucacggggc ccagcaccgg cgccgugggc cgcaacaucg     2520

aguucuccgg gaaggacagc aaggacgagg acggcaagau cgugagcuac gacugggacu     2580

ucggggacgg cgccaccucc cgggggaaga acagcgucca cgccuacaag aaggcgggca     2640

ccuacaacgu gacgcugaag gugaccgacg acaagggcgc caccgccacc gaguccuuca     2700

cgaucgagau caagaacgag gacaccacca cccccaucac gaaggagaug gagcccaacg     2760

acgacaucaa ggaggccaac gggccgaucg ucgagggcgu gaccgugaag ggggaccuca     2820

acggcagcga cgacgccgac accuucuacu ucgacgucaa ggaggacggg gacgugacca     2880

ucgagcugcc cuacuccggc agcuccaacu ucacguggcu gguguacaag gagggcgacg     2940

accagaacca caucgcgagc gggaucgaca agaacaacuc caaggucggc accuucaaga     3000

gcaccaaggg gcgccacuac guguucaucu acaagcacga cuccgccagc aacaucuccu     3060

acagccucaa caucaagggc cuggggaacg agaagcugaa ggagaaggag aacaacgacu     3120

ccagcgacaa ggccaccgug auccccaacu ucaacacgac caugcagggc ucccuccugg     3180

gcgacgacag ccgggacuac uacuccuucg aggucaagga ggagggggag gugaacaucg     3240

agcuggacaa gaaggacgag uucggcguga ccuggacccu ccaccccgag agcaacauca     3300

acgaccgcau cacguacggg caggucgacg gcaacaaggu gagcaacaag gugaagcugc     3360

ggccgggcaa guacuaccug cucgucuaca aguacuccgg gagcggcaac uacgagcugc     3420

gcgugaacaa gugaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  6325
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt1) 
       R6149/R6222

<400>  6325
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuc cuguucucca      120

gcgccuacuc caucgccaac accaacagcg agaaguacga cuucgaguac cugaacggcc      180

ucuccuacac cgagcugacc aaccugauca agaacaucaa guggaaccag aucaacgggc      240

ucuucaacua cagcacgggc ucccagaagu ucuucgggga caagaaccgc gugcaggcga      300

ucaucaacgc ccugcaggag agcggccgga ccuacaccgc caacgacaug aaggggaucg      360

agaccuucac ggagguccug cgcgccggcu ucuaccucgg cuacuacaac gacgggcugu      420

ccuaccugaa cgaccggaac uuccaggaca agugcauccc cgcgaugauc gccauccaga      480

agaaccccaa cuucaagcuc ggcaccgccg ugcaggacga ggugaucacc agccugggga      540

agcugaucgg caacgccagc gccaacgcgg aggucgugaa caacugcgug ccgguccuca      600

agcaguuccg cgagaaccug aaccaguacg cccccgacua cgugaagggg accgccguga      660

acgagcugau caagggcauc gaguucgacu ucuccggcgc cgccuacgag aaggacguca      720

agacgaugcc cugguacggg aagaucgacc ccuucaucaa cgagcucaag gcgcugggcc      780

uguacgggaa caucaccagc gccaccgagu gggccuccga cgugggcauc uacuaccuca      840

gcaaguucgg ccuguacucc accaaccgga acgacaucgu gcagagccug gagaaggccg      900

ucgacaugua caaguacggg aagaucgccu ucguggcgau ggagcgcauc acgugggacu      960

acgacggcau cggguccaac ggcaagaagg ucgaccacga caaguuccuc gacgacgccg     1020

agaagcacua ccugccgaag accuacaccu ucgacaacgg gaccuucauc auccgggccg     1080

gcgacaaggu gagcgaggag aagaucaagc gccuguacug ggccucccgg gaggugaaga     1140

gccaguucca ccgcgucgug ggcaacgaca aggcccucga gguggggaac gcggacgacg     1200

uccugacgau gaagaucuuc aacucccccg aggaguacaa guucaacacc aacaucaacg     1260

gcgugagcac cgacaacggg ggccuguaca ucgagccgcg ggggaccuuc uacacguacg     1320

agcgcacccc gcagcagucc aucuucagcc ucgaggagcu guuccggcac gaguacaccc     1380

acuaccugca ggcccgcuac cucguggacg gccugugggg ccaggggccg uucuacgaga     1440

agaaccggcu gaccugguuc gacgagggca cggccgaguu cuucgccggg uccacccgca     1500

ccagcggcgu ccucccccgg aaguccaucc ugggguaccu ggcgaaggac aagguggacc     1560

accgcuacag ccucaagaag acccugaacu ccggcuacga cgacagcgac uggauguucu     1620

acaacuacgg cuucgccgug gcccacuacc uguacgagaa ggacaugccc acguucauca     1680

agaugaacaa ggccauccug aacaccgacg ucaagagcua cgacgagauc aucaagaagc     1740

ucuccgacga cgccaacaag aacaccgagu accagaacca cauccaggag cuggcggaca     1800

aguaccaggg ggccggcauc ccccugguga gcgacgacua ccucaaggac cacggguaca     1860

agaaggccuc cgagguguac agcgagaucu ccaaggccgc cagccugacc aacaccuccg     1920

ucacggcgga gaagagccag uacuucaaca ccuucacccu gcgcggcacc uacacgggcg     1980

agaccuccaa gggggaguuc aaggacuggg acgagaugag caagaagcuc gacggcaccc     2040

uggagucccu ggccaagaac agcugguccg gguacaagac ccucacggcc uacuucacca     2100

acuaccgggu gaccagcgac aacaaggugc aguacgacgu cguguuccac ggcgugcuga     2160

ccgacaacgc cgacaucucc aacaacaagg ccccgaucgc gaaggucacg gggcccagca     2220

ccggcgccgu gggccgcaac aucgaguucu ccgggaagga cagcaaggac gaggacggca     2280

agaucgugag cuacgacugg gacuucgggg acggcgccac cucccggggg aagaacagcg     2340

uccacgccua caagaaggcg ggcaccuaca acgugacgcu gaaggugacc gacgacaagg     2400

gcgccaccgc caccgagucc uucacgaucg agaucaagaa cgaggacacc accaccccca     2460

ucacgaagga gauggagccc aacgacgaca ucaaggaggc caacgggccg aucgucgagg     2520

gcgugaccgu gaagggggac cucaacggca gcgacgacgc cgacaccuuc uacuucgacg     2580

ucaaggagga cggggacgug accaucgagc ugcccuacuc cggcagcucc aacuucacgu     2640

ggcuggugua caaggagggc gacgaccaga accacaucgc gagcgggauc gacaagaaca     2700

acuccaaggu cggcaccuuc aagagcacca aggggcgcca cuacguguuc aucuacaagc     2760

acgacuccgc cagcaacauc uccuacagcc ucaacaucaa gggccugggg aacgagaagc     2820

ugaaggagaa ggagaacaac gacuccagcg acaaggccac cgugaucccc aacuucaaca     2880

cgaccaugca gggcucccuc cugggcgacg acagccggga cuacuacucc uucgagguca     2940

aggaggaggg ggaggugaac aucgagcugg acaagaagga cgaguucggc gugaccugga     3000

cccuccaccc cgagagcaac aucaacgacc gcaucacgua cgggcagguc gacggcaaca     3060

aggugagcaa caaggugaag cugcggccgg gcaaguacua ccugcucguc uacaaguacu     3120

ccgggagcgg caacuacgag cugcgcguga acaagugagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  6326
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt1)

<400>  6326
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuc cuguucucca      120

gcgccuacuc caugaagaag aacauccuga agauccucau ggacagcuac uccaaggaga      180

gcaagaucca gaccgugcgc cgggucaccu ccgugagccu gcuggccgug uaccucacga      240

ugaacaccuc cagccugguc cuggccaagc ccaucgagaa caccaacgac accuccauca      300

agaacgugga gaagcuccgc aacgcgccca acgaggagaa cagcaagaag guggaggacu      360

ccaagaacga caaggucgag cacgugaaga acaucgagga ggccaaggug gagcaggucg      420

cccccgaggu gaagagcaag uccacgcugc ggagcgccuc ccgccggcgc cggaagcgca      480

ucgccaacac caacagcgag aaguacgacu ucgaguaccu gaacggccuc uccuacaccg      540

agcugaccaa ccugaucaag aacaucaagu ggaaccagau caacgggcuc uucaacuaca      600

gcacgggcuc ccagaaguuc uucggggaca agaaccgcgu gcaggcgauc aucaacgccc      660

ugcaggagag cggccggacc uacaccgcca acgacaugaa ggggaucgag accuucacgg      720

agguccugcg cgccggcuuc uaccucggcu acuacaacga cgggcugucc uaccugaacg      780

accggaacuu ccaggacaag ugcauccccg cgaugaucgc cauccagaag aaccccaacu      840

ucaagcucgg caccgccgug caggacgagg ugaucaccag ccuggggaag cugaucggca      900

acgccagcgc caacgcggag gucgugaaca acugcgugcc gguccucaag caguuccgcg      960

agaaccugaa ccaguacgcc cccgacuacg ugaaggggac cgccgugaac gagcugauca     1020

agggcaucga guucgacuuc uccggcgccg ccuacgagaa ggacgucaag acgaugcccu     1080

gguacgggaa gaucgacccc uucaucaacg agcucaaggc gcugggccug uacgggaaca     1140

ucaccagcgc caccgagugg gccuccgacg ugggcaucua cuaccucagc aaguucggcc     1200

uguacuccac caaccggaac gacaucgugc agagccugga gaaggccguc gacauguaca     1260

aguacgggaa gaucgccuuc guggcgaugg agcgcaucac gugggacuac gacggcaucg     1320

gguccaacgg caagaagguc gaccacgaca aguuccucga cgacgccgag aagcacuacc     1380

ugccgaagac cuacaccuuc gacaacggga ccuucaucau ccgggccggc gacaagguga     1440

gcgaggagaa gaucaagcgc cuguacuggg ccucccggga ggugaagagc caguuccacc     1500

gcgucguggg caacgacaag gcccucgagg uggggaacgc ggacgacguc cugacgauga     1560

agaucuucaa cucccccgag gaguacaagu ucaacaccaa caucaacggc gugagcaccg     1620

acaacggggg ccuguacauc gagccgcggg ggaccuucua cacguacgag cgcaccccgc     1680

agcaguccau cuucagccuc gaggagcugu uccggcacga guacacccac uaccugcagg     1740

cccgcuaccu cguggacggc cuguggggcc aggggccguu cuacgagaag aaccggcuga     1800

ccugguucga cgagggcacg gccgaguucu ucgccggguc cacccgcacc agcggcgucc     1860

ucccccggaa guccauccug ggguaccugg cgaaggacaa gguggaccac cgcuacagcc     1920

ucaagaagac ccugaacucc ggcuacgacg acagcgacug gauguucuac aacuacggcu     1980

ucgccguggc ccacuaccug uacgagaagg acaugcccac guucaucaag augaacaagg     2040

ccauccugaa caccgacguc aagagcuacg acgagaucau caagaagcuc uccgacgacg     2100

ccaacaagaa caccgaguac cagaaccaca uccaggagcu ggcggacaag uaccaggggg     2160

ccggcauccc ccuggugagc gacgacuacc ucaaggacca cggguacaag aaggccuccg     2220

agguguacag cgagaucucc aaggccgcca gccugaccaa caccuccguc acggcggaga     2280

agagccagua cuucaacacc uucacccugc gcggcaccua cacgggcgag accuccaagg     2340

gggaguucaa ggacugggac gagaugagca agaagcucga cggcacccug gagucccugg     2400

ccaagaacag cugguccggg uacaagaccc ucacggccua cuucaccaac uaccggguga     2460

ccagcgacaa caaggugcag uacgacgucg uguuccacgg cgugcugacc gacaacgccg     2520

acaucuccaa caacaaggcc ccgaucgcga aggucacggg gcccagcacc ggcgccgugg     2580

gccgcaacau cgaguucucc gggaaggaca gcaaggacga ggacggcaag aucgugagcu     2640

acgacuggga cuucggggac ggcgccaccu cccgggggaa gaacagcguc cacgccuaca     2700

agaaggcggg caccuacaac gugacgcuga aggugaccga cgacaagggc gccaccgcca     2760

ccgaguccuu cacgaucgag aucaagaacg aggacaccac cacccccauc acgaaggaga     2820

uggagcccaa cgacgacauc aaggaggcca acgggccgau cgucgagggc gugaccguga     2880

agggggaccu caacggcagc gacgacgccg acaccuucua cuucgacguc aaggaggacg     2940

gggacgugac caucgagcug cccuacuccg gcagcuccaa cuucacgugg cugguguaca     3000

aggagggcga cgaccagaac cacaucgcga gcgggaucga caagaacaac uccaaggucg     3060

gcaccuucaa gagcaccaag gggcgccacu acguguucau cuacaagcac gacuccgcca     3120

gcaacaucuc cuacagccuc aacaucaagg gccuggggaa cgagaagcug aaggagaagg     3180

agaacaacga cuccagcgac aaggccaccg ugauccccaa cuucaacacg accaugcagg     3240

gcucccuccu gggcgacgac agccgggacu acuacuccuu cgaggucaag gaggaggggg     3300

aggugaacau cgagcuggac aagaaggacg aguucggcgu gaccuggacc cuccaccccg     3360

agagcaacau caacgaccgc aucacguacg ggcaggucga cggcaacaag gugagcaaca     3420

aggugaagcu gcggccgggc aaguacuacc ugcucgucua caaguacucc gggagcggca     3480

acuacgagcu gcgcgugaac aagugaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  6327
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt1)

<400>  6327
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuga agaucauccu caaccgcggc aagaccauga      120

agcggaagug ccugagcaag cgccugaugc ucgccaucac cauggccacg aucuucaccg      180

ugaacuccac ccugcccauc uacgcggccg ucgacaagaa caacgccacc gccgccgugc      240

agaacgagag caagcgguac acgguguccu accugaagac ccucaacuac uacgaccugg      300

ucgaccugcu cgugaagacc gagaucgaga accugccgga ccuguuccag uacagcuccg      360

acgcgaagga guucuacggg aacaagaccc gcaugagcuu caucauggac gagaucggcc      420

ggcgcgcgcc ccaguacacg gagaucgacc acaaggggau ccccacccuc guggaggucg      480

ugcgggccgg cuucuaccug ggguuccaca acaaggagcu gaacgagauc aacaagcgcu      540

ccuucaagga gcgggugauc cccagcaucc ucgccaucca gaagaacccg aacuucaagc      600

ugggcaccga gguccaggac aagaucgugu ccgccaccgg ccugcucgcc gggaacgaga      660

cggccccgcc cgaggugguc aacaacuuca cccccauccu gcaggacugc aucaagaaca      720

ucgaccgcua cgcccuggac gaccucaaga gcaaggcccu guucaacgug cuggcggccc      780

cgaccuacga caucaccgag uaccuccggg ccacgaagga gaagcccgag aacacccccu      840

gguacggcaa gaucgacggg uucaucaacg agcugaagaa gcuggcccuc uacggcaaga      900

ucaacgacaa caacuccugg aucaucgaca acgggaucua ccacaucgcg ccccugggca      960

agcugcacag caacaacaag aucggcaucg agacccucac cgaggugaug aaggucuacc     1020

cguaccuguc caugcagcac cuccagagcg ccgaccagau caagcgccac uacgacucca     1080

aggacgccga ggggaacaag aucccccugg acaaguucaa gaaggagggc aaggagaagu     1140

acugccccaa gacguacacc uucgacgacg ggaaggugau caucaaggcc ggcgcccggg     1200

uggaggagga gaaggucaag cgccuguacu gggccagcaa ggaggugaac ucccaguucu     1260

uccgggugua cggcaucgac aagccccugg aggaggggaa cccggacgac auccucacca     1320

uggucaucua caacagcccc gaggaguaca agcugaacuc cgugcuguac ggcuacgaca     1380

ccaacaacgg gggcauguac aucgagcccg aggggacguu cuucaccuac gagcgcgagg     1440

cgcaggagag caccuacacc cucgaggagc uguuccggca cgaguacacg cacuaccugc     1500

agggccgcua cgccgugccc ggccaguggg ggcggaccaa gcucuacgac aacgaccgcc     1560

ugaccuggua cgaggagggc ggggccgagc uguucgccgg cagcacccgg acguccggga     1620

uccucccgcg caagagcauc gucuccaaca uccacaacac cacccgcaac aaccgguaca     1680

agcugagcga caccgugcac uccaaguacg gcgccagcuu cgaguucuac aacuacgcgu     1740

gcauguucau ggacuacaug uacaacaagg acaugggcau ccugaacaag cucaacgacc     1800

uggccaagaa caacgacguc gacggguacg acaacuacau ccgcgaccug uccagcaacu     1860

acgcccugaa cgacaaguac caggaccaca ugcaggagcg gaucgacaac uacgagaacc     1920

ucacggugcc cuucguggcc gacgacuacc ugguccgcca cgcguacaag aaccccaacg     1980

agaucuacuc cgagaucagc gagguggcca agcugaagga cgccaagucc gaggugaaga     2040

agucccagua cuucagcacc uucacccucc ggggcagcua caccgggggc gccuccaagg     2100

ggaagcugga ggaccagaag gccaugaaca aguucaucga cgacagccug aagaagcucg     2160

acaccuacuc cuggagcggc uacaagacgc ugaccgcgua cuucaccaac uacaaggucg     2220

acuccagcaa ccgcgugacc uacgacgugg ucuuccacgg cuaccugccc aacgaggggg     2280

acagcaagaa cucccucccg uacggcaaga ucaacgggac guacaagggc accgagaagg     2340

agaagaucaa guucagcucc gagggcagcu ucgaccccga cgggaagauc guguccuacg     2400

agugggacuu cggcgacggg aacaagagca acgaggagaa ccccgagcac uccuacgaca     2460

aggugggcac cuacaccguc aagcugaagg ugacggacga caagggggag agcuccguga     2520

gcaccaccac cgccgagauc aaggaccugu ccgagaacaa gcuccccguc aucuacaugc     2580

acgugcccaa gagcggcgcc cugaaccaga agguggucuu cuacggcaag gggacguacg     2640

accccgacgg cuccaucgcc ggguaccagu gggacuucgg cgacgggagc gacuucucca     2700

gcgagcagaa ccccucccac guguacacca agaagggcga guacaccgug acccugcggg     2760

ucauggacag cagcggccag auguccgaga agacgaugaa gaucaagauc accgacccgg     2820

uguaccccau cgggaccgag aaggagccca acaacagcaa ggagaccgcc uccggcccca     2880

ucgugccggg gauccccguc agcggcacga ucgagaacac cuccgaccag gacuacuucu     2940

acuucgacgu gaucaccccc ggggagguga agaucgacau caacaagcuc ggcuacggcg     3000

gggcgaccug ggucguguac gacgagaaca acaacgccgu gagcuacgcc acggacgacg     3060

gccagaaccu guccgggaag uucaaggccg acaagcccgg ccgcuacuac auccaccugu     3120

acauguucaa cgggagcuac augccguacc ggaucaacau cgagggcucc gucggccgcu     3180

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  6328
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt1)

<400>  6328
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcgcaagu gccugagcaa gcggcucaug cuggccauca      120

ccauggccac caucuucacg gugaacucca cccugcccau cuacgcggcc gucgacaaga      180

acaacgccac cgccgccgug cagaacgaga gcaagcgcua caccgugucc uaccucaaga      240

cgcugaacua cuacgaccug gucgaccucc uggugaagac cgagaucgag aaccugcccg      300

accucuucca guacagcucc gacgcgaagg aguucuacgg caacaagacc cggaugagcu      360

ucaucaugga cgagaucggg cgccgggccc cgcaguacac cgagaucgac cacaagggca      420

uccccacgcu gguggagguc gugcgcgccg gguucuaccu gggcuuccac aacaaggagc      480

ucaacgagau caacaagcgg uccuucaagg agcgcgugau ccccagcauc cuggccaucc      540

agaagaaccc gaacuucaag cuggggaccg agguccagga caagaucgug uccgcgaccg      600

gccuccuggc cggcaacgag accgccccgc ccgagguggu caacaacuuc acgcccaucc      660

ugcaggacug caucaagaac aucgaccggu acgcccucga cgaccugaag agcaaggccc      720

uguucaacgu gcucgcggcc ccgaccuacg acaucaccga guaccugcgc gccaccaagg      780

agaagcccga gaacacgccg ugguacggga agaucgacgg cuucaucaac gagcugaaga      840

agcucgcccu guacgggaag aucaacgaca acaacuccug gaucaucgac aacggcaucu      900

accacaucgc cccccugggg aagcuccaca gcaacaacaa gaucggcauc gagacccuga      960

ccgaggugau gaaggucuac ccguaccugu ccaugcagca ccuccagagc gcggaccaga     1020

ucaagcggca cuacgacucc aaggacgccg agggcaacaa gaucccccug gacaaguuca     1080

agaaggaggg gaaggagaag uacugcccca agaccuacac guucgacgac ggcaagguga     1140

ucaucaaggc cggggcccgc guggaggagg agaaggucaa gcggcuguac ugggccagca     1200

aggaggugaa cucccaguuc uuccgcgugu acggcaucga caagccccuc gaggagggca     1260

acccggacga cauccugacc auggucaucu acaacagccc cgaggaguac aagcugaacu     1320

ccgugcucua cggguacgac accaacaacg gcgggaugua caucgagccc gagggcaccu     1380

ucuucacgua cgagcgggag gcgcaggaga gcaccuacac ccuggaggag cuguuccgcc     1440

acgaguacac ccacuaccuc caggggcggu acgccgugcc cggccagugg ggccgcacga     1500

agcuguacga caacgaccgg cugaccuggu acgaggaggg cggcgccgag cucuucgccg     1560

ggagcacccg caccuccggg auccugccgc ggaagagcau cgucuccaac auccacaaca     1620

cgacccgcaa caaccgcuac aagcugagcg acaccgugca cuccaaguac ggggccagcu     1680

ucgaguucua caacuacgcg ugcauguuca uggacuacau guacaacaag gacaugggca     1740

uccucaacaa gcugaacgac cuggccaaga acaacgacgu cgacggcuac gacaacuaca     1800

uccgggaccu guccagcaac uacgcccuca acgacaagua ccaggaccac augcaggagc     1860

gcaucgacaa cuacgagaac cugaccgugc ccuucguggc cgacgacuac cugguccggc     1920

acgcguacaa gaaccccaac gagaucuacu ccgagaucag cgagguggcc aagcucaagg     1980

acgccaaguc cgaggugaag aagagccagu acuucuccac guucacccug cgcgggagcu     2040

acaccggcgg ggccuccaag ggcaagcugg aggaccagaa ggccaugaac aaguucaucg     2100

acgacagccu caagaagcug gacaccuacu ccuggagcgg guacaagacc cugacggcgu     2160

acuucaccaa cuacaagguc gacuccagca accgggugac cuacgacgug gucuuccacg     2220

gcuaccuccc caacgagggc gacagcaaga acucccugcc guacgggaag aucaacggca     2280

ccuacaaggg gacggagaag gagaagauca aguucagcuc cgagggcagc uucgaccccg     2340

acggcaagau cguguccuac gagugggacu ucggggacgg caacaagagc aacgaggaga     2400

accccgagca cuccuacgac aaggugggga ccuacaccgu caagcugaag gugaccgacg     2460

acaagggcga gagcuccgug agcacgacca ccgccgagau caaggaccuc uccgagaaca     2520

agcugcccgu caucuacaug cacgugccga agagcggggc ccugaaccag aagguggucu     2580

ucuacggcaa gggcaccuac gaccccgacg gguccaucgc cggcuaccag ugggacuucg     2640

gggacggcag cgacuucucc agcgagcaga accccuccca cguguacacg aagaaggggg     2700

aguacaccgu gacccuccgc gucauggaca gcagcggcca gauguccgag aagaccauga     2760

agaucaagau cacggacccg guguacccca ucggcaccga gaaggagccc aacaacagca     2820

aggagaccgc cuccgggccc aucgugccgg gcauccccgu cagcgggacc aucgagaaca     2880

cguccgacca ggacuacuuc uacuucgacg ugaucacccc cggcgaggug aagaucgaca     2940

ucaacaagcu gggguacggc ggcgcgaccu gggucgugua cgacgagaac aacaacgccg     3000

ugagcuacgc caccgacgac gggcagaacc uguccggcaa guucaaggcc gacaagcccg     3060

ggcgguacua cauccaccuc uacauguuca acggcagcua caugccguac cgcaucaaca     3120

ucgagggguc cgucggccgg ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  6329
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt1) 
       R6150/R6223

<400>  6329
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuc cuguucucca      120

gcgccuacuc cgugcagaac gagagcaagc gcuacaccgu guccuaccuc aagacgcuga      180

acuacuacga ccuggucgac cuccugguga agaccgagau cgagaaccug cccgaccucu      240

uccaguacag cuccgacgcg aaggaguucu acggcaacaa gacccggaug agcuucauca      300

uggacgagau cgggcgccgg gccccgcagu acaccgagau cgaccacaag ggcaucccca      360

cgcuggugga ggucgugcgc gccggguucu accugggcuu ccacaacaag gagcucaacg      420

agaucaacaa gcgguccuuc aaggagcgcg ugauccccag cauccuggcc auccagaaga      480

acccgaacuu caagcugggg accgaggucc aggacaagau cguguccgcg accggccucc      540

uggccggcaa cgagaccgcc ccgcccgagg uggucaacaa cuucacgccc auccugcagg      600

acugcaucaa gaacaucgac cgguacgccc ucgacgaccu gaagagcaag gcccuguuca      660

acgugcucgc ggccccgacc uacgacauca ccgaguaccu gcgcgccacc aaggagaagc      720

ccgagaacac gccgugguac gggaagaucg acggcuucau caacgagcug aagaagcucg      780

cccuguacgg gaagaucaac gacaacaacu ccuggaucau cgacaacggc aucuaccaca      840

ucgccccccu ggggaagcuc cacagcaaca acaagaucgg caucgagacc cugaccgagg      900

ugaugaaggu cuacccguac cuguccaugc agcaccucca gagcgcggac cagaucaagc      960

ggcacuacga cuccaaggac gccgagggca acaagauccc ccuggacaag uucaagaagg     1020

aggggaagga gaaguacugc cccaagaccu acacguucga cgacggcaag gugaucauca     1080

aggccggggc ccgcguggag gaggagaagg ucaagcggcu guacugggcc agcaaggagg     1140

ugaacuccca guucuuccgc guguacggca ucgacaagcc ccucgaggag ggcaacccgg     1200

acgacauccu gaccaugguc aucuacaaca gccccgagga guacaagcug aacuccgugc     1260

ucuacgggua cgacaccaac aacggcggga uguacaucga gcccgagggc accuucuuca     1320

cguacgagcg ggaggcgcag gagagcaccu acacccugga ggagcuguuc cgccacgagu     1380

acacccacua ccuccagggg cgguacgccg ugcccggcca guggggccgc acgaagcugu     1440

acgacaacga ccggcugacc ugguacgagg agggcggcgc cgagcucuuc gccgggagca     1500

cccgcaccuc cgggauccug ccgcggaaga gcaucgucuc caacauccac aacacgaccc     1560

gcaacaaccg cuacaagcug agcgacaccg ugcacuccaa guacggggcc agcuucgagu     1620

ucuacaacua cgcgugcaug uucauggacu acauguacaa caaggacaug ggcauccuca     1680

acaagcugaa cgaccuggcc aagaacaacg acgucgacgg cuacgacaac uacauccggg     1740

accuguccag caacuacgcc cucaacgaca aguaccagga ccacaugcag gagcgcaucg     1800

acaacuacga gaaccugacc gugcccuucg uggccgacga cuaccugguc cggcacgcgu     1860

acaagaaccc caacgagauc uacuccgaga ucagcgaggu ggccaagcuc aaggacgcca     1920

aguccgaggu gaagaagagc caguacuucu ccacguucac ccugcgcggg agcuacaccg     1980

gcggggccuc caagggcaag cuggaggacc agaaggccau gaacaaguuc aucgacgaca     2040

gccucaagaa gcuggacacc uacuccugga gcggguacaa gacccugacg gcguacuuca     2100

ccaacuacaa ggucgacucc agcaaccggg ugaccuacga cguggucuuc cacggcuacc     2160

uccccaacga gggcgacagc aagaacuccc ugccguacgg gaagaucaac ggcaccuaca     2220

aggggacgga gaaggagaag aucaaguuca gcuccgaggg cagcuucgac cccgacggca     2280

agaucguguc cuacgagugg gacuucgggg acggcaacaa gagcaacgag gagaaccccg     2340

agcacuccua cgacaaggug gggaccuaca ccgucaagcu gaaggugacc gacgacaagg     2400

gcgagagcuc cgugagcacg accaccgccg agaucaagga ccucuccgag aacaagcugc     2460

ccgucaucua caugcacgug ccgaagagcg gggcccugaa ccagaaggug gucuucuacg     2520

gcaagggcac cuacgacccc gacgggucca ucgccggcua ccagugggac uucggggacg     2580

gcagcgacuu cuccagcgag cagaaccccu cccacgugua cacgaagaag ggggaguaca     2640

ccgugacccu ccgcgucaug gacagcagcg gccagauguc cgagaagacc augaagauca     2700

agaucacgga cccgguguac cccaucggca ccgagaagga gcccaacaac agcaaggaga     2760

ccgccuccgg gcccaucgug ccgggcaucc ccgucagcgg gaccaucgag aacacguccg     2820

accaggacua cuucuacuuc gacgugauca cccccggcga ggugaagauc gacaucaaca     2880

agcuggggua cggcggcgcg accugggucg uguacgacga gaacaacaac gccgugagcu     2940

acgccaccga cgacgggcag aaccuguccg gcaaguucaa ggccgacaag cccgggcggu     3000

acuacaucca ccucuacaug uucaacggca gcuacaugcc guaccgcauc aacaucgagg     3060

gguccgucgg ccggugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6330
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt1)

<400>  6330
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuc cuguucucca      120

gcgccuacuc caugaagcgc aagugccuga gcaagcggcu caugcuggcc aucaccaugg      180

ccaccaucuu cacggugaac uccacccugc ccaucuacgc ggccgucgac aagaacaacg      240

ccaccgccgc ccgccggcgc cggaagcgcg ugcagaacga gagcaagcgc uacaccgugu      300

ccuaccucaa gacgcugaac uacuacgacc uggucgaccu ccuggugaag accgagaucg      360

agaaccugcc cgaccucuuc caguacagcu ccgacgcgaa ggaguucuac ggcaacaaga      420

cccggaugag cuucaucaug gacgagaucg ggcgccgggc cccgcaguac accgagaucg      480

accacaaggg cauccccacg cugguggagg ucgugcgcgc cggguucuac cugggcuucc      540

acaacaagga gcucaacgag aucaacaagc gguccuucaa ggagcgcgug auccccagca      600

uccuggccau ccagaagaac ccgaacuuca agcuggggac cgagguccag gacaagaucg      660

uguccgcgac cggccuccug gccggcaacg agaccgcccc gcccgaggug gucaacaacu      720

ucacgcccau ccugcaggac ugcaucaaga acaucgaccg guacgcccuc gacgaccuga      780

agagcaaggc ccuguucaac gugcucgcgg ccccgaccua cgacaucacc gaguaccugc      840

gcgccaccaa ggagaagccc gagaacacgc cgugguacgg gaagaucgac ggcuucauca      900

acgagcugaa gaagcucgcc cuguacggga agaucaacga caacaacucc uggaucaucg      960

acaacggcau cuaccacauc gccccccugg ggaagcucca cagcaacaac aagaucggca     1020

ucgagacccu gaccgaggug augaaggucu acccguaccu guccaugcag caccuccaga     1080

gcgcggacca gaucaagcgg cacuacgacu ccaaggacgc cgagggcaac aagauccccc     1140

uggacaaguu caagaaggag gggaaggaga aguacugccc caagaccuac acguucgacg     1200

acggcaaggu gaucaucaag gccggggccc gcguggagga ggagaagguc aagcggcugu     1260

acugggccag caaggaggug aacucccagu ucuuccgcgu guacggcauc gacaagcccc     1320

ucgaggaggg caacccggac gacauccuga ccauggucau cuacaacagc cccgaggagu     1380

acaagcugaa cuccgugcuc uacggguacg acaccaacaa cggcgggaug uacaucgagc     1440

ccgagggcac cuucuucacg uacgagcggg aggcgcagga gagcaccuac acccuggagg     1500

agcuguuccg ccacgaguac acccacuacc uccaggggcg guacgccgug cccggccagu     1560

ggggccgcac gaagcuguac gacaacgacc ggcugaccug guacgaggag ggcggcgccg     1620

agcucuucgc cgggagcacc cgcaccuccg ggauccugcc gcggaagagc aucgucucca     1680

acauccacaa cacgacccgc aacaaccgcu acaagcugag cgacaccgug cacuccaagu     1740

acggggccag cuucgaguuc uacaacuacg cgugcauguu cauggacuac auguacaaca     1800

aggacauggg cauccucaac aagcugaacg accuggccaa gaacaacgac gucgacggcu     1860

acgacaacua cauccgggac cuguccagca acuacgcccu caacgacaag uaccaggacc     1920

acaugcagga gcgcaucgac aacuacgaga accugaccgu gcccuucgug gccgacgacu     1980

accugguccg gcacgcguac aagaacccca acgagaucua cuccgagauc agcgaggugg     2040

ccaagcucaa ggacgccaag uccgagguga agaagagcca guacuucucc acguucaccc     2100

ugcgcgggag cuacaccggc ggggccucca agggcaagcu ggaggaccag aaggccauga     2160

acaaguucau cgacgacagc cucaagaagc uggacaccua cuccuggagc ggguacaaga     2220

cccugacggc guacuucacc aacuacaagg ucgacuccag caaccgggug accuacgacg     2280

uggucuucca cggcuaccuc cccaacgagg gcgacagcaa gaacucccug ccguacggga     2340

agaucaacgg caccuacaag gggacggaga aggagaagau caaguucagc uccgagggca     2400

gcuucgaccc cgacggcaag aucguguccu acgaguggga cuucggggac ggcaacaaga     2460

gcaacgagga gaaccccgag cacuccuacg acaagguggg gaccuacacc gucaagcuga     2520

aggugaccga cgacaagggc gagagcuccg ugagcacgac caccgccgag aucaaggacc     2580

ucuccgagaa caagcugccc gucaucuaca ugcacgugcc gaagagcggg gcccugaacc     2640

agaagguggu cuucuacggc aagggcaccu acgaccccga cggguccauc gccggcuacc     2700

agugggacuu cggggacggc agcgacuucu ccagcgagca gaaccccucc cacguguaca     2760

cgaagaaggg ggaguacacc gugacccucc gcgucaugga cagcagcggc cagauguccg     2820

agaagaccau gaagaucaag aucacggacc cgguguaccc caucggcacc gagaaggagc     2880

ccaacaacag caaggagacc gccuccgggc ccaucgugcc gggcaucccc gucagcggga     2940

ccaucgagaa cacguccgac caggacuacu ucuacuucga cgugaucacc cccggcgagg     3000

ugaagaucga caucaacaag cugggguacg gcggcgcgac cugggucgug uacgacgaga     3060

acaacaacgc cgugagcuac gccaccgacg acgggcagaa ccuguccggc aaguucaagg     3120

ccgacaagcc cgggcgguac uacauccacc ucuacauguu caacggcagc uacaugccgu     3180

accgcaucaa caucgagggg uccgucggcc ggugaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  6331
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt1)

<400>  6331
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggccgcgu      120

ucgccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc agcuacgagg      180

ugcucacccc gcugaagugg uaccagucca uccgcccgcc cuaccccagc uacggcuacg      240

agcccauggg cggguggcug caccaccaga ucauccccgu ccucucccag cagcacccgc      300

ccacgcacac ccugcagccg caccaccaca uccccguggu gcccgcccag cagcccguca      360

ucccccagca gcccaugaug cccgugcccg gccagcacag caugaccccg auccagcacc      420

accagcccaa ccugcccccg ccggcccagc agcccuacca gccccagccc gugcagcccc      480

agccccacca gcccaugcag ccgcagccgc ccguccaccc caugcagccg cucccgcccc      540

agcccccgcu gccgcccaug uuccccaugc agccccugcc gcccaugcuc cccgaccuga      600

cccuggaggc cuggcccucc acggacaaga ccaagcggga ggagguggac ugaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  6332
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt1)

<400>  6332
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucagcuacga ggugcucacc ccgcugaagu gguaccaguc cauccgcccg cccuacccca      180

gcuacggcua cgagcccaug ggcggguggu gaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  6333
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt1)

<400>  6333
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucagcuacga ggugcucacc ccgcugaagu gguaccaguc cauccgcccg ccgcccaugc      180

uccccgaccu gacccuggag gccuggcccu ccacggacaa gaccaagcgg gaggaggugg      240

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  6334
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt1)

<400>  6334
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg ccccgcggac ccugguccuc cugcugagcg      120

gcgcgcucgc ccugacccag acgugggcca ugccccugcc gccccacccc ggccaccccg      180

gguacaucaa cuucagcuac gaggugcuca ccccgcugaa gugguaccag uccauccgcc      240

cgcccuaccc cagcuacggc uacgagccca ugggcgggug gugaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  6335
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt1)

<400>  6335
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg ccccgcggac ccugguccuc cugcugagcg      120

gcgcgcucgc ccugacccag acgugggcca ugccccugcc gccccacccc ggccaccccg      180

gguacaucaa cuucagcuac gaggugcuca ccccgcugaa gugguaccag uccauccgcc      240

cgccgcccau gcuccccgac cugacccugg aggccuggcc cuccacggac aagaccaagc      300

gggaggaggu ggacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  6336
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt1)

<400>  6336
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccucgug ggggccgcgu      120

ucgccaugcc ccugccgccc caccccggcc accccgggua caucaacuuc agcuacgagg      180

uccugacccc gcucaagugg uaccagucca ugauccgccc gcccuacagc uccuacggcu      240

acgagcccau gggcgggugg cugcaccacc agaucauccc cguggugagc cagcagcacc      300

cccugacgca cacccuccag ucccaccacc acauccccgu cgugcccgcc cagcagccgc      360

gggugcgcca gcaggcccug augcccgucc ccggccagca gagcaugacc cccacccagc      420

accaccagcc gaaccugccc cuccccgccc agcagcccuu ccagccgcag cccgugcagc      480

cccagcccca ccagccgaug cagccccagc cgcccgugca gcccaugcag ccccugcugc      540

cccagccgcc ccucccgccc auguuccccc ugcggccccu gccgcccauc cuccccgacc      600

ugcaccugga ggcguggccc gccacggaca agaccaagca ggaggagguc gacugaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  6337
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt1)

<400>  6337
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucagcuacga gguccugacc ccgcucaagu gguaccaguc caugauccgc ccgcccuaca      180

gcuccuacgg cuacgagccc augggcgggu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6338
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt1)

<400>  6338
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucagcuacga gguccugacc ccgcucaagu gguaccaguc caugauccgc ccgccgccca      180

uccuccccga ccugcaccug gaggcguggc ccgccacgga caagaccaag caggaggagg      240

ucgacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6339
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt1)

<400>  6339
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg ccccgcggac ccugguccuc cugcugagcg      120

gcgcgcucgc ccugacccag acgugggcca ugccccugcc gccccacccc ggccaccccg      180

gguacaucaa cuucagcuac gagguccuga ccccgcucaa gugguaccag uccaugaucc      240

gcccgcccua cagcuccuac ggcuacgagc ccaugggcgg guggugagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6340
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt1)

<400>  6340
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg ccccgcggac ccugguccuc cugcugagcg      120

gcgcgcucgc ccugacccag acgugggcca ugccccugcc gccccacccc ggccaccccg      180

gguacaucaa cuucagcuac gagguccuga ccccgcucaa gugguaccag uccaugaucc      240

gcccgccgcc cauccucccc gaccugcacc uggaggcgug gcccgccacg gacaagacca      300

agcaggagga ggucgacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6341
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt1)

<400>  6341
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggccgcgu      120

ucagcaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacgagg      180

ugcucacccc gcugaagugg uaccagaaca ugauccgcca ccccuacacg agcuacggcu      240

acgagcccau gggcgggugg cugcaccacc agaucauccc cgucgugucc cagcagaccc      300

cgcagagcca cgcccuccag ccccaccacc acauccccau ggugcccgcc cagcagccgg      360

gcauccccca gcagcccaug augccccugc cggggcagca cuccaugacc cccacccagc      420

accaccagcc caaccugccc cucccggccc agcagcccuu ccagccccag cccguccagc      480

cgcagcccca ccagccccug cagccccaga gcccgaugca ccccauccag ccccugcucc      540

cgcagccgcc ccugcccccg auguucucca ugcagagccu gcuccccgac cugccccugg      600

aggccuggcc cgcgacggac aagaccaagc gggaggaggu ggacugagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6342
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt1)

<400>  6342
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucuccuacga ggugcucacc ccgcugaagu gguaccagaa caugauccgc caccccuaca      180

cgagcuacgg cuacgagccc augggcgggu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6343
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt1)

<400>  6343
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucuccuacga ggugcucacc ccgcugaagu gguaccagaa caugauccgc caccccagcc      180

ugcuccccga ccugccccug gaggccuggc ccgcgacgga caagaccaag cgggaggagg      240

uggacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6344
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt1)

<400>  6344
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg ccccgcggac ccugguccuc cugcugagcg      120

gcgcgcucgc ccugacccag acgugggcca ugccccugcc gccccacccc ggccaccccg      180

gguacaucaa cuucuccuac gaggugcuca ccccgcugaa gugguaccag aacaugaucc      240

gccaccccua cacgagcuac ggcuacgagc ccaugggcgg guggugagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6345
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt1)

<400>  6345
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg ccccgcggac ccugguccuc cugcugagcg      120

gcgcgcucgc ccugacccag acgugggcca ugccccugcc gccccacccc ggccaccccg      180

gguacaucaa cuucuccuac gaggugcuca ccccgcugaa gugguaccag aacaugaucc      240

gccaccccag ccugcucccc gaccugcccc uggaggccug gcccgcgacg gacaagacca      300

agcgggagga gguggacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6346
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt1)

<400>  6346
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggccgcgu      120

ucagcaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacaucc      180

gccacccgua caccagcuac ggcuacgagc ccaugggcgg guggcuccac caccagauca      240

uccccguggu cucccagcag acgccccaga gccacgcccu gcagccgcac caccacaucc      300

ccauggugcc cgcccagcag cccggcaucc cgcagcagcc caugaugccc cugcccgggc      360

agcacuccau gaccccgacc cagcaccacc agcccaaccu cccccugccc gcccagcagc      420

cguuccagcc ccagcccgug cagccccagc cgcaccagcc ccugcagccc cagagcccca      480

ugcacccgau ccagccccuc cugccccagc cgccccugcc gcccauguuc uccaugcaga      540

gccuccugcc cgaccugccc cucgaggccu ggcccgcgac cgacaagacg aagcgggagg      600

aggucgacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  6347
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt1)

<400>  6347
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuucgc cugccugcuc ggggccagcc      120

uggcgaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacgagg      180

ugcucacgcc ccugaagugg uaccagaaca ugauccgcca ccccuacacc agcuacggcu      240

acgagcccau gggcgggugg cugcaccacc agaucauccc cgucgugucc cagcagaccc      300

cgcagagcca cgcccuccag ccccaccacc acauccccau ggugcccgcc cagcagccgg      360

gcauccccca gcagcccaug augccccugc cggggcagca cuccaugacc cccacccagc      420

accaccagcc caaccugccc cucccggccc agcagcccuu ccagccccag cccguccagc      480

cgcagcccca ccagccccug cagccccaga gcccgaugca ccccauccag ccccugcucc      540

cgcagccgcc ccugccgccc auguucucca ugcagagccu gcuccccgac cugccccugg      600

aggccuggcc cgcgacggac aagaccaagc gggaggaggu ggacugagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6348
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt1)

<400>  6348
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggccgcgu      120

ucagcaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacgagg      180

ugcucacccc gcugaagugg uaccagaaca ugauccgcca ccccagccug cuccccgacc      240

ugccccugga ggccuggccg gccacggaca agaccaagcg ggaggagguc gacugaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  6349
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt1)

<400>  6349
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggccgcgu      120

ucagcaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacgagg      180

accucuaccu ggaggccauc cgcaucgacc ggaccgccuu cgugcugacg ccccucaagu      240

gguaccagaa caugauccgc caccccuaca ccagcuacgg cuacgagccc augggcgggu      300

ggcugcacca ccagaucauc cccgucgugu cccagcagac cccgcagagc cacgcccugc      360

agccccacca ccacaucccc auggugcccg cccagcagcc gggcaucccc cagcagccca      420

ugaugccccu cccggggcag cacuccauga cccccacgca gcaccaccag cccaaccugc      480

cccugccggc gcagcagccc uuccagcccc agcccgucca gccgcagccc caccagcccc      540

uccagcccca gagcccgaug caccccaucc agccccugcu gccgcagccg ccccugccgc      600

ccauguucuc caugcagagc cuccugcccg accucccccu ggaggccugg cccgccaccg      660

acaagaccaa gcgggaggag guggacugag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  6350
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt1)

<400>  6350
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggccgcgu      120

ucagcaugcc ccugccgccc caccccggcc accccgggua caucaacuuc uccuacgagg      180

ugcucacccc gcugaagugg uaccagaaca ugauccgcca ccccacgccc cagagccacg      240

cccugcagcc ccaccaccac aucccgaugg uccccgccca gcagcccggc aucccccagc      300

agccgaugau gccccucccc gggcagcacu ccaugacccc cacccagcac caccagccga      360

accugccccu gcccgcccag cagcccuucc agccgcagcc cgugcagccc cagccccacc      420

agccgcucca gccccagagc cccaugcacc ccauccagcc gcugcugccc cagcccccgc      480

ucccgcccau guucuccaug cagagccugc ugcccgaccu cccccuggag gccuggcccg      540

cgaccgacaa gacgaagcgg gaggaggugg acugaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  6351
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt1)

<400>  6351
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccgc cccaccccgg ccaccccggg uacaucaacu      120

ucagcuacga ggugcucacc ccgcugaagu gguaccagaa caugauccgc caccccuaca      180

ccuccuacgg cuacgagccc augggcgggu ggcugcacca ccagaucauc cccgucguga      240

gccagcagac gccgcagucc cacgcccucc agccccacca ccacaucccc auggugcccg      300

cccagcagcc cgggaucccc cagcagccca ugaugccccu gccgggccag cacagcauga      360

cccccaccca gcaccaccag cccaaccugc cccucccggc gcagcagccc uuccagcccc      420

agcccgucca gccgcagccc caccagcccc ugcagcccca guccccgaug caccccaucc      480

agccccugcu cccgcagccg ccccugccgc ccauguucag caugcagucc cugcuccccg      540

accugccccu ggaggccugg cccgccaccg acaagacgaa gcgggaggag guggacugag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  6352
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt1)

<400>  6352
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg cccgccugcc gcuccugcug gggcuccugc      120

ugcucccccg gcccggccgc ccccuggacc uggccgacua caccuacgac cucgccgagg      180

aggacgacag cgagccgcug aacuacaagg accccugcaa ggccgccgcc uuccuggggg      240

acaucgcccu cgacgaggag gaccugcggg cguuccaggu ccagcaggcc guggaccugc      300

gccggcacac cgcccgcaag uccagcauca aggccgcggu gcccggcaac acguccaccc      360

ccagcugcca guccaccaac gggcagccgc agcggggcgc cugcggccgc uggcgggggc      420

gcagccgguc ccgccgggcc gccaccagcc gccccgagcg ggucuggccc gacggcguga      480

uccccuucgu gaucgggggc aacuucacgg ggucccagcg cgccgucuuc cggcaggcga      540

ugcgccacug ggagaagcac acgugcguga ccuuccucga gcggaccgac gaggacagcu      600

acaucguguu caccuaccgc ccgugcggcu gcugcuccua cgucggccgg cgcgggggcg      660

ggccccaggc caucagcauc ggcaagaacu gcgacaaguu cggcaucgug gugcacgagc      720

uggggcacgu cgugggcuuc uggcacgagc acacccgccc cgaccgggac cgccacgugu      780

ccaucguccg ggagaacauc cagcccgggc aggaguacaa cuuccugaag auggagccgc      840

aggaggugga gagccucggc gagaccuacg acuucgacuc caucaugcac uacgcccgca      900

acaccuucag ccgggggauc uuccuggaca cgaucgugcc caaguacgag gucaacggcg      960

ugaagccgcc caucggccag cgcacccggc uguccaaggg ggacaucgcc caggcccgca     1020

agcucuacaa gugccccgcg ugcggcgaga cccugcagga cagcaccggg aacuucucca     1080

gccccgagua ccccaacggc uacagcgccc acaugcacug cguguggcgg aucuccguca     1140

cgcccgggga gaagaucauc cugaacuuca ccagccucga ccuguaccgc ucccggcugu     1200

gcugguacga cuacguggag gugcgcgacg gcuucuggcg gaaggccccg cuccgcggcc     1260

gguucugcgg gagcaagcug cccgagccca ucgucuccac cgacagccgc cugugggugg     1320

aguuccgguc cagcuccaac ugggucggca agggguucuu cgccguguac gaggccaucu     1380

gcggcgggga cgugaagaag gacuacggcc acauccagag ccccaacuac ccggacgacu     1440

accgccccuc caaggucugc aucuggcgga uccaggugag cgagggcuuc cacguggggc     1500

ucaccuucca guccuucgag aucgagcgcc acgacagcug cgcguacgac uaccuggagg     1560

uccgcgacgg ccacuccgag agcuccacgc ugaucgggcg guacugcggc uacgagaagc     1620

ccgacgacau caagagcacc uccagccgcc ucuggcugaa guucgugagc gacggcucca     1680

ucaacaaggc cggguucgcc gugaacuucu ucaaggaggu cgacgagugc agccggccga     1740

accgcggcgg gugcgagcag cggugccuga acacccucgg cuccuacaag ugcagcugcg     1800

accccgggua cgagcuggcc cccgacaagc gccggugcga ggccgcgugc ggcggcuucc     1860

ugaccaagcu caacgggucc aucacgagcc ccggcuggcc gaaggaguac ccgcccaaca     1920

agaacugcau cuggcagcug guggccccca cccaguaccg caucucccug caguucgacu     1980

ucuucgagac cgaggggaac gacgugugca aguacgacuu cgucgaggug cggagcggcc     2040

ucaccgccga cuccaagcug cacgggaagu ucugcggcag cgagaagccc gaggugauca     2100

cgucccagua caacaacaug cgcgucgagu ucaagagcga caacaccgug uccaagaagg     2160

gcuucaaggc ccacuucuuc agcgacaagg acgagugcuc caaggacaac gggggcugcc     2220

agcaggacug cgugaacacc uucgggagcu acgagugcca gugccggucc ggcuucgucc     2280

ugcacgacaa caagcacgac ugcaaggagg cggggugcga ccacaaggug accagcacga     2340

gcggcaccau caccuccccc aacuggcccg acaaguaccc cagcaagaag gagugcaccu     2400

gggccaucuc cagcacgccg ggccaccgcg ugaagcucac cuucauggag auggacaucg     2460

agucccagcc cgagugcgcc uacgaccacc uggaggucuu cgacgggcgg gacgccaagg     2520

cccccgugcu gggccgcuuc ugcgggagca agaagcccga gccggugcuc gcgaccggcu     2580

cccggauguu ccugcgcuuc uacagcgaca acuccgucca gcggaagggg uuccaggcca     2640

gccacgccac cgagugcggc ggccaggugc gcgccgacgu gaagaccaag gaccuguacu     2700

cccacgccca guucggggac aacaacuacc ccggcggggu cgacugcgag ugggugaucg     2760

uggcggagga gggcuacggc gucgagcugg uguuccagac guucgaggug gaggaggaga     2820

ccgacugcgg guacgacuac auggagcugu ucgacggcua cgacagcacc gcgccccggc     2880

ucgggcgcua cugcggcucc gggcccccgg aggaggucua cagcgccggc gacuccgugc     2940

uggugaaguu ccacagcgac gacaccauca cgaagaaggg cuuccaccuc cgguacaccu     3000

ccaccaaguu ccaggacacc cugcacagcc gcaagugagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  6353
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt1)

<400>  6353
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggca cccgcugccu gcucgcccug cugcuccccc      120

agguccugcu cgggggcgcg gccgggcugg ugccggagcu gggccggcgc aaguucgccg      180

ccgccagcuc cgggcggccc agcucccagc ccagcgacga ggugcugucc gaguucgagc      240

uccgccugcu gagcauguuc ggccucaagc agcggcccac cccgucccgc gacgcggucg      300

ugccgcccua caugcuggac cuguaccggc gccacagcgg ccagcccggg ucccccgccc      360

ccgaccaccg gcucgagcgc gccgccagcc gggcgaacac ggugcgcucc uuccaccacg      420

aggagagccu ggaggagcug cccgagaccu ccggcaagac cacccggcgc uucuucuuca      480

accucagcuc cauccccacg gaggaguuca ucaccagcgc cgagcugcag gucuuccggg      540

agcagaugca ggacgcccug gggaacaacu ccagcuucca ccaccgcauc aacaucuacg      600

agaucaucaa gccggccacc gccaacucca aguuccccgu gacccggcuc cuggacacgc      660

gccuggugaa ccagaacgcg agccgguggg agagcuucga cgucaccccc gccgugaugc      720

gcuggaccgc ccagggccac gccaaccacg gguucguggu cgagguggcc caccucgagg      780

agaagcaggg cguguccaag cggcacgucc gcaucagccg cucccugcac caggacgagc      840

acagcugguc ccagauccgg ccccugcucg ugaccuucgg ccacgacggg aagggccacc      900

cgcugcacaa gcgcgagaag cggcaggcga agcacaagca gcgcaagcgg cucaagagcu      960

ccugcaagcg ccacccccug uacguggacu ucagcgacgu cggguggaac gacuggaucg     1020

uggccccgcc cggcuaccac gccuucuacu gccacggcga gugccccuuc ccccuggccg     1080

accaccugaa cuccacgaac cacgccaucg ugcagacccu cgucaacagc gugaacucca     1140

agauccccaa ggcgugcugc gugcccaccg agcugagcgc caucuccaug cuguaccucg     1200

acgagaacga gaaggucgug cugaagaacu accaggacau ggucguggag gggugcggcu     1260

gccggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  6354
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt1)

<400>  6354
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auccccggca accgcaugcu gauggugguc cuccugugcc      120

aggugcugcu cgggggcgcc agccacgccu cccugauccc ggagaccggg aagaagaagg      180

uggcggagau ccagggccac gccgggggcc ggcgcagcgg ccagucccac gagcugcucc      240

gggacuucga ggccacccug cugcagaugu ucgggcuccg ccggcgcccc cagcccagca      300

aguccgccgu cauccccgac uacaugcggg accuguaccg ccugcagagc ggcgaggagg      360

aggaggagca gauccacucc acggggcucg aguacccgga gcggcccgcc agccgcgcga      420

acaccgugcg guccuuccac cacgaggagc accuggagaa cauccccggc accagcgaga      480

acuccgccuu ccgcuuccug uucaaccuca gcuccauccc cgagaacgag gugaucagcu      540

ccgccgagcu gcggcuguuc cgcgagcagg ucgaccaggg gccggacugg gagcggggcu      600

uccaccgcau caacaucuac gaggugauga agccgcccgc cgaggugguc cccggccacc      660

ucaucacccg gcugcuggac acgcgccucg ugcaccacaa cgugacccgg ugggagaccu      720

ucgacgucag ccccgcggug cugcgcugga cccgggagaa gcagcccaac uacgggcugg      780

ccaucgaggu gacgcaccuc caccagaccc gcacccacca gggccagcac guccgcaucu      840

cccggagccu gccccagggg uccggcaacu gggcccagcu gcgcccccuc cuggugaccu      900

ucggccacga cgggcggggc cacgcccuga cgcgccggcg ccgggccaag cgcagcccga      960

agcaccacag ccagcgggcg cgcaagaaga acaagaacug ccggcgccac ucccucuacg     1020

uggacuucag cgacgucggg uggaacgacu ggaucguggc cccgcccggc uaccaggccu     1080

ucuacugcca cggggacugc cccuuccccc uggccgacca ccugaacucc accaaccacg     1140

ccaucgugca gacccucguc aacagcguga acuccagcau ccccaaggcg ugcugcgugc     1200

ccaccgagcu guccgccauc agcaugcugu accucgacga guacgacaag gucgugcuga     1260

agaacuacca ggagaugguc guggagggcu gcggcugccg gugaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  6355
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt1)

<400>  6355
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggccugg ggcgccgggc ccaguggcuc ugcugguggu      120

ggggccugcu gugcagcugc ugcgggccgc cgccccuccg gccgccccug cccgccgcgg      180

ccgccgccgc cgcgggcggg cagcugcucg gcgacggcgg gucccccggc cggaccgagc      240

agcccccgcc cagcccccag uccagcuccg gguuccugua ccgccggcug aagacccagg      300

agaagcgcga gaugcagaag gagauccuca gcgugcuggg ccugccccac cggccccgcc      360

cccuccacgg gcugcagcag ccccagcccc cggcccugcg gcagcaggag gagcagcagc      420

agcagcagca gcucccccgc ggcgagcccc cgcccggccg gcugaagucc gcgccccugu      480

ucaugcucga ccuguacaac gcccugagcg ccgacaacga cgaggacggg gccuccgagg      540

gcgagcgcca gcagagcugg ccccacgagg ccgccuccag cucccagcgg cgccagcccc      600

cgcccggggc cgcgcacccc cucaaccgca agagccugcu ggcccccggc uccggcagcg      660

ggggcgccuc cccgcucacg agcgcccagg acuccgccuu ccugaacgac gcggacaugg      720

ucaugagcuu cgugaaccug guggaguacg acaaggaguu cagcccccgc cagcggcacc      780

acaaggaguu caaguucaac cucucccaga uccccgaggg ggaggucgug accgccgccg      840

aguuccgcau cuacaaggac ugcgugaugg gcagcuucaa gaaccagacc uuccugaucu      900

ccaucuacca gguccugcag gagcaccagc accgggacag cgaccucuuc cugcuggaca      960

cccgcguggu gugggccucc gaggaggggu ggcucgaguu cgacaucacg gccaccagca     1020

accugugggu cgugaccccg cagcacaaca ugggccugca gcucuccgug gucacccggg     1080

acggcgugca cgugcacccc cgcgcggccg ggcuggucgg ccgcgacggg cccuacgaca     1140

agcagcccuu caugguggcc uucuucaagg ugagcgaggu ccacgugcgg acgacccgcu     1200

ccgccagcuc ccggcgccgg cagcagagcc gcaaccgguc cacccagagc caggacgugg     1260

cccgcgucuc cagcgcgucc gacuacaaca gcuccgagcu gaagaccgcc ugccggaagc     1320

acgagcucua cgugagcuuc caggaccugg gcuggcagga cuggaucauc gccccgaagg     1380

gguacgccgc gaacuacugc gacggcgagu gcagcuuccc ccugaacgcc cacaugaacg     1440

ccacgaacca cgccaucgug cagacccucg uccaccugau gaaccccgag uacgugccca     1500

agccgugcug cgcccccacc aagcugaacg cgaucuccgu ccucuacuuc gacgacaaca     1560

gcaacgugau ccugaagaag uaccgcaaca uggugguccg ggccugcggc ugccacugag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  6356
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt1)

<400>  6356
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugcgca gccugcgggc cgccgcgccc cacuccuucg      120

ucgcccucug ggccccgcug uuccugcucc gcagcgcccu ggccgacuuc ucccuggaca      180

acgaggugca cagcuccuuc auccaccggc gccuccggag ccaggagcgc cgggagaugc      240

agcgcgagau ccuguccauc cugggccucc cccaccggcc ccgcccccac cuccagggga      300

agcacaacag cgcgccgaug uucaugcugg accuguacaa cgccauggcc guggaggagg      360

gcgggggccc cgggggccag ggcuucuccu accccuacaa ggccgucuuc agcacccagg      420

ggcccccgcu ggcgucccug caggacagcc acuuccucac cgacgccgac auggugaugu      480

ccuucgugaa ccuggucgag cacgacaagg aguucuucca cccccgguac caccaccgcg      540

aguuccgguu cgaccugagc aagauccccg agggcgaggc cgugacggcc gccgaguucc      600

gcaucuacaa ggacuacauc cgggagcgcu ucgacaacga gaccuuccgg aucuccgugu      660

accagguccu ccaggagcac cuggggcgcg agagcgaccu guuccuccug gacucccgga      720

cccugugggc gagcgaggag ggcuggcucg uguucgacau caccgccacg uccaaccacu      780

ggguggucaa cccccgccac aaccuggggc ugcagcucag cguggagacc cuggacggcc      840

agagcaucaa cccgaagcug gccggccuca ucgggcggca cggcccccag aacaagcagc      900

ccuucauggu ggccuucuuc aaggccaccg agguccacuu ccgcuccauc cgcagcaccg      960

gguccaagca gcggagccag aaccgcucca agacgcccaa gaaccaggag gcgcugcgga     1020

uggccaacgu ggccgagaac agcuccagcg accagcgcca ggccugcaag aagcacgagc     1080

uguacguguc cuuccgggac cucggcuggc aggacuggau caucgccccg gagggcuacg     1140

cggccuacua cugcgagggg gagugcgccu ucccccugaa cagcuacaug aacgccacca     1200

accacgccau cguccagacc cuggugcacu ucaucaaccc cgagaccgug cccaagccgu     1260

gcugcgcgcc cacgcagcuc aacgccaucu ccguccugua cuucgacgac agcuccaacg     1320

ugauccugaa gaaguaccgc aacauggugg uccgggccug cggcugccac ugaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  6357
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt1)

<400>  6357
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggccagcg ccgcgcugcu cugccugcug cucaccgccg      120

ccgccuucag cccccagggc cuggcccagc cgguggggau caacaccucc acgaccugcu      180

gcuaccgcuu caucaacaag aagaucccca agcagcggcu ggaguccuac cgccggacca      240

ccagcuccca cugcccccgc gaggcgguca ucuucaagac gaagcucgac aaggagaucu      300

gcgccgaccc cacccagaag ugggugcagg acuucaugaa gcaccuggac aagaagaccc      360

agaccccgaa gcugugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  6358
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt1)

<400>  6358
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucaccc ugaucauccu gcuccccgug gucagcaagu      120

ucuccuucgu gagccugucc gcgccccagc acuggagcug ccccgagggc acccuggccg      180

ggaacggcaa cuccacgugc guggggcccg cccccuuccu caucuucagc cacggcaacu      240

ccaucuuccg caucgacacc gaggggacca acuacgagca gcuggucgug gacgccggcg      300

ugagcgucau cauggacuuc cacuacaacg agaagcggau cuacugggug gaccuggagc      360

gccagcuccu gcagcgggug uuccugaacg gcucccgcca ggagcggguc ugcaacaucg      420

agaagaacgu gagcgggaug gccaucaacu ggaucaacga ggaggugauc ugguccaacc      480

agcaggaggg caucaucacc gucacggaca ugaaggggaa caacagccac auccuccugu      540

ccgcccugaa guacccggcc aacguggcgg uggaccccgu cgagcgcuuc aucuucugga      600

gcuccgaggu ggccggcagc cucuaccggg ccgaccugga cggggugggc gucaaggccc      660

ugcucgagac cuccgagaag aucaccgcgg ugagccugga cgugcuggac aagcgccucu      720

ucuggaucca guacaaccgg gagggcucca acagccugau cugcagcugc gacuacgacg      780

ggggcuccgu ccacaucagc aagcacccca cccagcacaa ccuguucgcc augucccucu      840

ucggggaccg caucuucuac agcacgugga agaugaagac caucuggauc gccaacaagc      900

acaccggcaa ggacauggug cggaucaacc ugcacuccag cuucgugccc cugggcgagc      960

ucaaggucgu gcacccgcug gcccagccca aggccgagga cgacaccugg gagcccgagc     1020

agaagcugug caagcuccgc aaggggaacu gcuccagcac ggucugcggc caggaccugc     1080

agucccaccu gugcaugugc gcggaggggu acgcccucag ccgggaccgc aaguacugcg     1140

aggacgugaa cgagugcgcc uucuggaacc acggcugcac ccuggggugc aagaacaccc     1200

ccggcuccua cuacugcacg ugcccggugg gcuucguccu gcuccccgac gggaagcggu     1260

gccaccagcu ggugagcugc ccccgcaacg uguccgagug cagccacgac ugcguccuga     1320

ccuccgaggg cccccucugc uucugcccgg aggggagcgu gcuggagcgg gacggcaaga     1380

ccugcuccgg gugcagcucc cccgacaacg gcggcugcag ccagcugugc gugccccuca     1440

gccccgucuc cugggagugc gacugcuucc cgggguacga ccugcagcug gacgagaagu     1500

ccugcgccgc cagcggcccc cagcccuucc uccuguucgc gaacagccag gacauccgcc     1560

acaugcacuu cgacgggacc gacuacggca cccugcucuc ccagcagaug gggauggugu     1620

acgcccugga ccacgacccc guggagaaca agaucuacuu cgcccacacg gcccugaagu     1680

ggaucgagcg ggccaacaug gacggcagcc agcgcgagcg gcugaucgag gagggcgucg     1740

acgugccgga ggggcucgcg guggacugga ucggccgccg cuucuacugg accgaccggg     1800

ggaagucccu gaucggccgc agcgaccuga acggcaagcg guccaagauc aucaccaagg     1860

agaacaucag ccagccccgc gggaucgccg uccaccccau ggccaagcgc cucuucugga     1920

ccgacacggg caucaacccc cggaucgagu ccagcucccu gcaggggcug ggccggcucg     1980

ugaucgccag cuccgaccug aucuggccga gcgggaucac caucgacuuc cugaccgaca     2040

agcucuacug gugcgacgcc aagcaguccg ugaucgagau ggcgaaccug gacggcagca     2100

agcgccggcg ccugacccag aacgacgucg gccaccccuu cgccguggcc guguucgagg     2160

acuacgucug guucagcgac ugggccaugc ccuccgugau gcgggugaac aagcgcacgg     2220

ggaaggaccg gguccgccuc cagggcagca ugcugaagcc guccagccug gugguggucc     2280

acccccucgc gaagcccggg gccgaccccu gccuguacca gaacggcggg ugcgagcaca     2340

ucugcaagaa gcggcugggc accgccuggu gcuccugccg cgagggcuuc augaaggcca     2400

gcgacgggaa gaccugccuc gcccuggacg gccaccagcu gcucgccggg ggcgaggugg     2460

accugaagaa ccaggugacc ccgcuggaca uccucuccaa gacgcggguc agcgaggaca     2520

acaucaccga gucccagcac augcuggugg ccgagaucau ggugagcgac caggacgacu     2580

gcgcccccgu cgggugcucc auguacgccc gcugcaucag cgagggcgag gacgcgaccu     2640

gccagugccu gaagggcuuc gcgggggacg gcaagcucug cuccgacauc gacgagugcg     2700

agaugggggu gcccgugugc ccgccggcca gcuccaagug caucaacacc gagggcgggu     2760

acgucugccg gugcagcgag ggcuaccagg gcgacgggau ccacugccug gacaucgacg     2820

agugccagcu gggcgagcac uccugcgggg agaacgccag cugcacgaac accgagggcg     2880

gcuacacgug caugugcgcc gggcgccucu ccgagcccgg ccugaucugc cccgacagca     2940

cgcccccgcc ccaccuccgc gaggacgacc accacuacag cgugcggaac uccgacagcg     3000

agugcccccu gucccacgac ggguacugcc ugcacgacgg cgugugcaug uacaucgagg     3060

cccuggacaa guacgcgugc aacugcgucg ugggguacau cggcgagcgc ugccaguacc     3120

gggaccucaa guggugggag cugcgccacg ccggccacgg gcagcagcag aaggugaucg     3180

ucguggccgu gugcgucgug gugcugguca ugcuccugcu gcucagccug uggggcgccc     3240

acuacuaccg gacccagaag cugcucucca agaaccccaa gaacccguac gaggagagcu     3300

cccgcgacgu gcggagccgc cggcccgcgg acaccgagga cgggaugucc agcugccccc     3360

agcccugguu cguggucauc aaggagcacc aggaccugaa gaacggcggg cagccggugg     3420

ccggcgagga cggccaggcc gccgacgggu ccaugcagcc caccagcugg cgccaggagc     3480

cccagcugug cggcaugggg accgagcagg gcugcuggau ccccgucucc agcgacaagg     3540

gguccugccc ccaggugaug gagcggagcu uccacaugcc cuccuacggc acccagaccc     3600

ucgagggcgg gguggagaag ccccacagcc ugcuguccgc caacccgcuc uggcagcagc     3660

gcgcgcugga cccgccccac cagauggagc ugacccagug aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  6359
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt1)

<400>  6359
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggcc gccggaugga gaugcugugc gccgggcgcg      120

ugcccgcgcu ccugcugugc cucggcuucc accuccugca ggccguccug agcaccacgg      180

ugaucccguc cugcaucccc ggggagagcu ccgacaacug caccgcccug gugcagaccg      240

aggacaaccc ccgggucgcc caggugagca ucaccaagug cuccagcgac augaacggcu      300

acugccugca cgggcagugc aucuaccucg uggacauguc ccagaacuac ugccgcugcg      360

aggucggcua cacgggcgug cggugcgagc acuucuuccu gaccgugcac cagccccuga      420

gcaaggagua cgucgcccuc accgugaucc ugaucauccu guuccucauc accguggucg      480

gguccacgua cuacuucugc cgcugguacc ggaaccgcaa gagcaaggag ccgaagaagg      540

aguacgagcg ggugaccucc ggcgaccccg agcugcccca ggugugagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  6360
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt1)

<400>  6360
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgagggcg agaucaccac cuucacggcc cugaccgaga      120

aguucaaccu gcccccgggg aacuacaaga agcccaagcu ccuguacugc agcaacggcg      180

ggcacuuccu ccgcauccug cccgacggca ccguggacgg gacccgggac cgcuccgacc      240

agcacaucca gcugcagcuc agcgcggagu ccgucggcga gguguacauc aagagcacgg      300

agaccggcca guaccuggcc auggacaccg acgggcugcu cuacggcucc cagaccccca      360

acgaggagug ccuguuccug gagcggcucg aggagaacca cuacaacacg uacaucagca      420

agaagcacgc cgagaagaac ugguucgugg ggcugaagaa gaacggcucc ugcaagcgcg      480

ggccgcggac ccacuacggc cagaaggcca uccuguuccu cccccugccc gucagcuccg      540

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  6361
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt1)

<400>  6361
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggcgucg ggggcgggga cguggaggac gugaccccgc      120

gcccgggcgg gugccagauc agcggccggg gcgcccgcgg gugcaacggc auccccgggg      180

ccgcggccug ggaggccgcc cugccccggc gccggccccg ccggcacccg uccgucaacc      240

cccgcagccg ggccgcgggc agcccccgca cccgggggcg ccggacggag gagcgccccu      300

ccggcucccg gcucggcgac cgcgggcggg gccgcgcccu gcccgggggc cggcugggcg      360

ggcgcggccg ggggcgcgcc cccgagcgcg ugggcgggcg gggccgcggc cgggggaccg      420

ccgcgccccg cgccgccccc gccgcccggg gcagccgccc ggggcccgcg ggcaccaugg      480

ccgccggguc caucaccacg cuccccgccc ugcccgagga cggcggcagc ggggccuucc      540

cgcccggcca cuucaaggac cccaagcggc uguacugcaa gaacgggggc uucuuccucc      600

gcauccaccc cgacgggcgg guggacggcg uccgcgagaa guccgacccg cacaucaagc      660

ugcagcugca ggcggaggag cggggcgugg ugagcaucaa gggggucugc gccaaccgcu      720

accucgccau gaaggaggac ggccggcugc uggccuccaa gugcgugacc gacgagugcu      780

ucuucuucga gcgccucgag agcaacaacu acaacaccua ccggucccgc aaguacacca      840

gcugguacgu ggcccugaag cggacggggc aguacaagcu gggcuccaag accggccccg      900

ggcagaaggc gauccucuuc cugcccauga gcgccaaguc cugaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  6362
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt1)

<400>  6362
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uccugaccug gauccucccc acccugcugu      120

accgcagcug cuuccacauc aucugccucg ugggcacgau cucccuggcc ugcaacgaca      180

ugaccccgga gcagauggcc accaacguca acugcagcuc ccccgagcgg cacacccgca      240

gcuacgacua cauggagggc ggggacaucc gggugcgccg gcuguucugc cgcacgcagu      300

gguaccuccg gaucgacaag cgcgggaagg ugaagggcac ccaggagaug aagaacaacu      360

acaacaucau ggagauccgg accgucgcgg uggggaucgu ggccaucaag ggcgucgagu      420

ccgaguucua ccuggccaug aacaaggagg gcaagcugua cgccaagaag gagugcaacg      480

aggacugcaa cuucaaggag cucauccugg agaaccacua caacaccuac gccagcgcga      540

aguggacgca caacgggggc gagauguucg uggcccugaa ccagaagggg auccccgugc      600

gcggcaagaa gaccaagaag gagcagaaga ccgcccacuu ccuccccaug gccaucaccu      660

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  6363
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt1)

<400>  6363
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugcucc ccagcguggu ccugaagcug uuccucgccg      120

ccgugcuguc cgcgcuggug accggcgaga gccucgagcg gcugcggcgc gggcuggccg      180

ccggcaccuc caacccggac ccgcccacgg ucagcaccga ccagcuccug ccccucgggg      240

gcgggcggga ccgcaaggug cgggaccugc aggaggccga ccuggaccug cuccgcguga      300

cccuguccag caagccccag gcccuggcga cccccaacaa ggaggagcac ggcaagcgga      360

agaagaaggg caaggggcuc ggcaagaagc gcgaccccug ccugcggaag uacaaggacu      420

ucugcaucca cggggagugc aaguacguca aggagcugcg cgcccccucc ugcaucugcc      480

acccgggcua ccacggggag cggugccacg gccucagccu gcccguggag aaccgccugu      540

acacguacga ccacaccacc auccucgccg uggucgccgu ggugcugucc agcgucugcc      600

ugcucgugau cgugggccug cugauguucc gguaccaccg ccgcgggggc uacgacgucg      660

agaacgagga gaaggugaag cucgggauga ccaacuccca cugaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  6364
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt1)

<400>  6364
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccugcug cuccagcacg      120

uccugcugca ccuccugcug cucccgaucg ccauccccua cgcggagggc cagcgcaagc      180

ggcgcaacac cauccacgag uucaagaagu ccgccaagac gacccugauc aagaucgacc      240

ccgcccugaa gaucaagacc aagaagguga acaccgccga ccagugcgcc aaccggugca      300

cgcgcaacaa ggggcucccc uucacgugca aggcguucgu guucgacaag gcccggaagc      360

agugccugug guucccguuc aacagcauga gcuccggcgu caagaaggag uucgggcacg      420

aguucgaccu guacgagaac aaggacuaca uccgcaacug caucaucggc aaggggcgga      480

gcuacaaggg caccgugucc aucaccaaga gcggcaucaa gugccagccc ugguccagca      540

ugauccccca cgagcacucc uuccucccca gcuccuaccg cgggaaggac cugcaggaga      600

acuacugccg gaacccgcgc ggcgaggagg gcgggcccug gugcuucacc agcaaccccg      660

aggugcggua cgaggucugc gacauccccc agugcuccga gguggagugc augaccugca      720

acggggagag cuaccgcggc cugauggacc acaccgaguc cggcaagauc ugccagcggu      780

gggaccacca gaccccgcac cgccacaagu uccuccccga gcgguacccc gacaaggggu      840

ucgacgacaa cuacugccgc aaccccgacg gccagccgcg gcccuggugc uacacgcugg      900

acccccacac ccgcugggag uacugcgcca ucaagaccug cgccgacaac accaugaacg      960

acacggacgu gccccuggag accaccgagu gcauccaggg gcagggcgag ggcuaccggg     1020

ggaccgucaa cacgaucugg aacggcaucc cgugccagcg cugggacagc caguaccccc     1080

acgagcacga caugaccccc gagaacuuca agugcaagga ccuccgggag aacuacugcc     1140

gcaaccccga cggguccgag agcccguggu gcuucaccac cgaccccaac auccgcgugg     1200

gcuacugcuc ccagaucccc aacugcgaca ugagccacgg gcaggacugc uaccggggca     1260

acggcaagaa cuacaugggg aaccugagcc agacgcgcuc cggccugacc ugcagcaugu     1320

gggacaagaa cauggaggac cuccaccggc acaucuucug ggagcccgac gcguccaagc     1380

ugaacgagaa cuacugccgc aacccggacg acgacgccca cgggcccugg ugcuacaccg     1440

gcaacccccu gaucccgugg gacuacugcc ccaucagccg gugcgagggg gacaccacgc     1500

ccaccaucgu gaaccucgac caccccguca ucuccugcgc caagaccaag cagcugcgcg     1560

uggugaacgg caucccgacc cggacgaaca ucggcuggau ggucagccug cgcuaccgga     1620

acaagcacau cugcgggggc ucccucauca aggagagcug ggugcugacc gcccgccagu     1680

gcuuccccuc ccgggaccug aaggacuacg aggccuggcu cgggauccac gacgugcacg     1740

gccgcgggga cgagaagugc aagcaggucc ugaacgugag ccagcuggug uacggccccg     1800

agggcuccga ccucguccug augaagcugg cgcggcccgc cgugcucgac gacuucguga     1860

gcaccaucga ccugccgaac uacgggugca ccauccccga gaagacgucc ugcagcgucu     1920

acggcugggg guacaccggc cugaucaacu acgacggccu ccugcgcgug gcccaccugu     1980

acaucauggg gaacgagaag ugcucccagc accaccgggg caaggucacc cucaacgaga     2040

gcgagaucug cgccggggcc gagaagaucg gcuccgggcc cugcgagggc gacuacggcg     2100

ggccccuggu gugcgagcag cacaagaugc gcauggugcu gggcgucauc gugccggggc     2160

ggggcugcgc gauccccaac cgccccggga ucuucgugcg ggucgccuac uacgccaagu     2220

ggauccacaa gaucauccuc accuacaagg ugccccagag cugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  6365
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt1)

<400>  6365
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggccg cggccaucgg caucgaccug gggaccaccu      120

acagcugcgu gggcguguuc cagcacggga agguggagau caucgccaac gaccagggca      180

accgcacgac ccccuccuac guggccuuca ccgacaccga gcggcucauc ggggacgccg      240

cgaagaacca ggucgcccug aacccgcaga acacgguguu cgacgccaag cgccugaucg      300

gccggaaguu cggcgacccc gugguccaga gcgacaugaa gcacuggccc uuccagguga      360

ucaacgacgg ggacaagccc aaggugcagg ucuccuacaa gggcgagacc aaggccuucu      420

acccggagga gaucagcucc auggugcuca ccaagaugaa ggagaucgcg gaggccuacc      480

ugggguaccc cgugaccaac gccgucauca cggugcccgc cuacuucaac gacagccagc      540

gccaggccac caaggacgcg ggcgugaucg ccgggcugaa cguccuccgg aucaucaacg      600

agcccaccgc cgccgccauc gcguacggcc uggaccgcac cggcaagggg gagcggaacg      660

ugcugaucuu cgaccucggc gggggcacgu ucgacguguc cauccugacc aucgacgacg      720

gcaucuucga ggucaaggcc accgccgggg acacccaccu gggcggggag gacuucgaca      780

accgccucgu gaaccacuuc guggaggagu ucaagcggaa gcacaagaag gacaucagcc      840

agaacaagcg cgccguccgg cgccugcgga cggccugcga gcgcgcgaag cggacccugu      900

ccagcuccac ccaggccagc cucgagaucg acucccuguu cgagggcauc gacuucuaca      960

ccagcaucac gcgcgcccgg uucgaggagc ugugcuccga ccucuuccgc agcacccugg     1020

agccggugga gaaggcccug cgggacgcca agcucgacaa ggcgcagauc cacgaccugg     1080

ugcuggucgg gggcuccacc cgcaucccca aggugcagaa gcuccugcag gacuucuuca     1140

acggccggga ccugaacaag agcaucaacc ccgacgaggc cgucgccuac ggggccgcgg     1200

ugcaggccgc cauccucaug ggcgacaagu ccgagaacgu gcaggaccug cugcuccugg     1260

acgucgcgcc ccugagccuc gggcuggaga ccgccggcgg ggugaugacg gcccugauca     1320

agcgcaacag caccaucccg accaagcaga cccagaucuu cacgaccuac uccgacaacc     1380

agcccggcgu gcucauccag gucuacgagg gcgagcgcgc caugaccaag gacaacaacc     1440

ugcuggggcg guucgagcuc agcggcaucc cgcccgcgcc ccgcggggug ccccagaucg     1500

aggugaccuu cgacaucgac gccaacggca uccugaacgu cacggccacc gacaagucca     1560

ccgggaaggc caacaagauc accaucacga acgacaaggg ccggcugagc aaggaggaga     1620

ucgagcgcau ggugcaggag gccgagaagu acaaggccga ggacgaggug cagcgggagc     1680

gcgucuccgc caagaacgcc cucgagagcu acgcguucaa caugaagucc gccguggagg     1740

acgagggccu gaaggggaag aucagcgagg ccgacaagaa gaaggugcug gacaagugcc     1800

aggaggucau cuccuggcuc gacgccaaca cccuggcgga gaaggacgag uucgagcaca     1860

agcggaagga gcuggagcag gucugcaacc ccaucaucag cggccucuac cagggggccg     1920

gcggccccgg gccgggcggg uucggcgccc aggggcccaa gggcggcucc gggagcggcc     1980

ccaccaucga ggagguggac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6366
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt1)

<400>  6366
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggccg cggccaucgg caucgaccug gggaccaccu      120

acagcugcgu gggcguguuc cagcacggga agguggagau caucgccaac gaccagggca      180

accgcacgac ccccuccuac guggccuuca ccgacaccga gcggcucauc ggggacgccg      240

cgaagaacca ggucgcccug aacccgcaga acacgguguu cgacgccaag cgccugaucg      300

gccggaaguu cggcgacccc gugguccaga gcgacaugaa gcacuggccc uuccagguga      360

ucaacgacgg ggacaagccc aaggugcagg ucuccuacaa gggcgagacc aaggccuucu      420

acccggagga gaucagcucc auggugcuca ccaagaugaa ggagaucgcg gaggccuacc      480

ugggguaccc cgugaccaac gccgucauca cggugcccgc cuacuucaac gacagccagc      540

gccaggccac caaggacgcg ggcgugaucg ccgggcugaa cguccuccgg aucaucaacg      600

agcccaccgc cgccgccauc gcguacggcc uggaccgcac cggcaagggg gagcggaacg      660

ugcugaucuu cgaccucggc gggggcacgu ucgacguguc cauccugacc aucgacgacg      720

gcaucuucga ggucaaggcc accgccgggg acacccaccu gggcggggag gacuucgaca      780

accgccucgu gaaccacuuc guggaggagu ucaagcggaa gcacaagaag gacaucagcc      840

agaacaagcg cgccguccgg cgccugcgga cggccugcga gcgcgcgaag cggacccugu      900

ccagcuccac ccaggccagc cucgagaucg acucccuguu cgagggcauc gacuucuaca      960

ccagcaucac gcgcgcccgg uucgaggagc ugugcuccga ccucuuccgc agcacccugg     1020

agccggugga gaaggcccug cgggacgcca agcucgacaa ggcgcagauc cacgaccugg     1080

ugcuggucgg gggcuccacc cgcaucccca aggugcagaa gcuccugcag gacuucuuca     1140

acggccggga ccugaacaag agcaucaacc ccgacgaggc cgucgccuac ggggccgcgg     1200

ugcaggccgc cauccucaug ggcgacaagu ccgagaacgu gcaggaccug cugcuccugg     1260

acgucgcgcc ccugagccuc gggcuggaga ccgccggcgg ggugaugacg gcccugauca     1320

agcgcaacag caccaucccg accaagcaga cccagaucuu cacgaccuac uccgacaacc     1380

agcccggcgu gcucauccag gucuacgagg gcgagcgcgc caugaccaag gacaacaacc     1440

ugcuggggcg guucgagcuc agcggcaucc cgcccgcgcc ccgcggggug ccccagaucg     1500

aggugaccuu cgacaucgac gccaacggca uccugaacgu cacggccacc gacaagucca     1560

ccgggaaggc caacaagauc accaucacga acgacaaggg ccggcugagc aaggaggaga     1620

ucgagcgcau ggugcaggag gccgagaagu acaaggccga ggacgaggug cagcgggagc     1680

gcgucuccgc caagaacgcc cucgagagcu acgcguucaa caugaagucc gccguggagg     1740

acgagggccu gaaggggaag aucagcgagg ccgacaagaa gaaggugcug gacaagugcc     1800

aggaggucau cuccuggcuc gacgccaaca cccuggcgga gaaggacgag uucgagcaca     1860

agcggaagga gcuggagcag gucugcaacc ccaucaucag cggccucuac cagggggccg     1920

gcggccccgg gccgggcggg uucggcgccc aggggcccaa gggcggcucc gggagcggcc     1980

ccaccaucga ggagguggac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6367
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt1)

<400>  6367
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaccgcca agggcaucgc gaucgggauc gaccugggca      120

ccacguacag cugcgugggg gucuuccagc acggcaaggu ggagaucauc gccaacgacc      180

aggggaaccg caccaccccc uccuacgugg ccuucaccga cacggagcgg cucaucggcg      240

acgccgccaa gaaccagguc gcgaugaacc cgcagaacac cguguucgac gccaagcgcc      300

ugaucggccg gaaguucaac gaccccgugg uccaggccga caugaagcug uggcccuucc      360

aggugaucaa cgagggcggg aagcccaagg ugcucgucag cuacaagggg gagaacaagg      420

ccuucuaccc ggaggagauc uccagcaugg ugcugaccaa gcugaaggag accgcggagg      480

ccuuccucgg ccaccccgug acgaacgccg ucaucaccgu gcccgccuac uucaacgacu      540

cccagcgcca ggccaccaag gacgcggggg ugaucgccgg ccugaacguc cugcggauca      600

ucaacgagcc caccgccgcc gccaucgcgu acggccucga caagggcggg cagggggagc      660

gccacgugcu gaucuucgac cugggcggcg ggacguucga cgugagcauc cucaccaucg      720

acgacggcau cuucgagguc aaggccaccg ccggggacac ccaccugggc ggggaggacu      780

ucgacaaccg gcuggugucc cacuucgugg aggaguucaa gcgcaagcac aagaaggaca      840

ucagccagaa caagcgggcc guccgccggc uccgcacggc cugcgagcgg gcgaagcgca      900

cccuguccag cuccacccag gccaaccugg agaucgacag ccucuacgag ggcaucgacu      960

ucuacaccuc caucacgcgg gcccgcuucg aggagcugug cgccgaccug uuccggggca     1020

cccucgagcc gguggagaag gcccugcgcg acgcgaagau ggacaaggcc aagauccacg     1080

acaucgugcu ggucgggggc agcacccgga uccccaaggu gcagcgccuc cugcaggacu     1140

acuucaacgg gcgggaccug aacaagucca ucaaccccga cgaggccguc gccuacggcg     1200

cggccgugca ggccgccauc cucauggggg acaagagcga gaaggugcag gaccugcugc     1260

uccuggacgu cgcgccccug ucccucggcc uggagaccgc cggcggggug augacggccc     1320

ugaucaagcg caacagcacc aucccgacca agcagaccca gaucuucacg accuacuccg     1380

acaaccagcc cggcgugcuc auccaggucu acgaggggga gcgcgccaug accaaggaca     1440

acaaccugcu gggccgguuc gaccucaccg ggaucccgcc cgcgccccgc ggcgugcccc     1500

agaucgaggu gacguucgac aucgacgcca acggcauccu gaacgucacc gccaccgaca     1560

agagcaccgg gaaggugaac aagaucacga ucaccaacga caagggccgg cugagcaagg     1620

aggagaucga gcgcauggug cucgacgccg agaaguacaa ggccgaggac gagguccagc     1680

gggagaagau cgccgccaag aacgcgcugg aguccuacgc cuucaacaug aaguccgugg     1740

ugagcgacga ggggcugaag ggcaagauca gcgaguccga caagaacaag auccucgaca     1800

agugcaacga gcugcugagc uggcucgagg ucaaccagcu ggccgagaag gacgaguucg     1860

accacaagcg caaggagcug gagcagaugu gcaaccccau caucaccaag cuguaccagg     1920

gcgggugcac cggccccgcc ugcgggaccg gcuacgugcc ggggcggccc gcgacgggcc     1980

ccaccaucga ggagguggac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6368
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt1)

<400>  6368
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgcccgcg gccccgccau cgggaucgac cugggcacca      120

ccuacuccug cguggggguc uuccagcacg gcaaggugga gaucaucgcg aacgaccagg      180

ggaaccggac gaccccgagc uacguggccu ucaccgacac cgagcgccuc aucggcgacg      240

ccgccaagaa ccaggucgcc augaacccca cgaacaccau cuucgacgcg aagcggcuga      300

ucggccgcaa guucgaggac gccaccgugc aguccgacau gaagcacugg cccuuccggg      360

uggucagcga gggcgggaag cccaaggucc agguggagua caagggggag accaagacgu      420

ucuucccgga ggagaucucc agcauggugc ugaccaagau gaaggagauc gccgaggccu      480

accucggcgg gaaggugcac uccgcgguga ucaccguccc cgccuacuuc aacgacagcc      540

agcgccaggc caccaaggac gccggcacga ucaccggccu gaacgugcug cggaucauca      600

acgagcccac cgccgcggcc aucgccuacg ggcucgacaa gaagggcugc gccgggggcg      660

agaagaacgu gcugaucuuc gaccugggcg ggggcaccuu cgacgucucc auccucacga      720

ucgaggacgg gaucuucgag gucaagagca ccgccggcga cacccaccuc gggggcgagg      780

acuucgacaa ccgcauggug ucccaccugg cggaggaguu caagcggaag cacaagaagg      840

acaucggccc caacaagcgc gccgugcggc gccugcggac cgccugcgag cgcgccaagc      900

ggacgcugag cuccagcacc caggccucca ucgagaucga cagccuguac gagggggugg      960

acuucuacac cuccaucacc cgcgcgcggu ucgaggagcu caacgccgac cuguuccgcg     1020

gcacgcugga gccgguggag aaggcccucc gggacgccaa gcuggacaag gggcagaucc     1080

aggagaucgu ccuggugggc gggagcaccc gcauccccaa gauccagaag cuccugcagg     1140

acuucuucaa cggcaaggag cugaacaagu ccaucaaccc cgacgaggcc guggcguacg     1200

gcgccgccgu ccaggccgcg auccucaucg gggacaagag cgagaacgug caggaccugc     1260

ugcuccugga cgucacgccc cugagccucg gcaucgagac cgccgggggc gugaugaccc     1320

cgcugaucaa gcggaacacc accaucccca ccaagcagac gcagaccuuc accaccuacu     1380

ccgacaacca gagcuccgug cugguccagg uguacgaggg ggagcgcgcc augacgaagg     1440

acaacaaccu ccugggcaag uucgaccuga ccggcauccc gcccgcgccc cgcggggugc     1500

cccagaucga ggucaccuuc gacaucgacg ccaacggcau ccucaacgug accgccgccg     1560

acaagagcac cgggaaggag aacaagauca cgaucaccaa cgacaagggc cggcugucca     1620

aggacgacau cgaccgcaug gugcaggagg ccgagcggua caagagcgag gacgaggcca     1680

accgcgaccg ggucgccgcg aagaacgccc uggaguccua caccuacaac aucaagcaga     1740

ccguggagga cgagaagcuc cgcggcaaga ucagcgagca ggacaagaac aagauccugg     1800

acaagugcca ggaggugauc aacuggcugg accggaacca gauggccgag aaggacgagu     1860

acgagcacaa gcagaaggag cucgagcgcg ucugcaaccc caucaucucc aagcuguacc     1920

agggcgggcc cgggggcggg agcggcggcg ggggcuccgg ggccagcggc gggccgacga     1980

ucgaggaggu ggacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  6369
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt1)

<400>  6369
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccag uccugcuacg      120

uggccguggc ccgcgcgggc gggaucgaga ccaucgccaa cgaguacagc gaccggugca      180

cccccgccug caucuccuuc ggcccgaaga accgcagcau cggggccgcc gcgaaguccc      240

aggucaucag caacgccaag aacacggugc agggcuucaa gcgguuccac ggccgcgccu      300

ucuccgaccc cuucguggag gccgagaagu ccaaccucgc guacgacauc guccagcugc      360

ccaccgggcu gaccggcauc aaggugaccu acauggagga ggagcggaac uucacgaccg      420

agcaggucac cgccaugcuc cugagcaagc ugaaggagac cgccgagagc gugcucaaga      480

agcccguggu ggacugcguc guguccgugc cgugcuucua cacggacgcc gagcgccgga      540

gcgucaugga cgccacccag aucgcggggc ugaacugccu gcgccucaug aacgagacca      600

ccgccguggc ccuggccuac ggcaucuaca agcaggaccu gcccgcccuc gaggagaagc      660

cccggaacgu ggucuucgug gacauggggc acuccgcgua ccaggugagc gucugcgccu      720

ucaaccgcgg caagcugaag gugcuggcca cggccuucga caccacccuc ggcgggcgga      780

aguucgacga ggugcugguc aaccacuucu gcgaggaguu cggcaagaag uacaagcugg      840

acaucaaguc caagauccgc gcccuccugc ggcugagcca ggagugcgag aagcucaaga      900

agcugauguc cgcgaacgcc agcgaccugc cccucuccau cgagugcuuc augaacgacg      960

uggacgucag cgggaccaug aaccgcggca aguuccugga gaugugcaac gaccugcucg     1020

cccgggugga gccgccccug cgcagcgugc uggagcagac gaagcucaag aaggaggaca     1080

ucuacgccgu cgagaucgug ggcggggcca cccggauccc cgcggugaag gagaagaucu     1140

ccaaguucuu cggcaaggag cugagcacca cccugaacgc cgacgaggcc gucacgcgcg     1200

ggugcgcccu ccagugcgcg auccuguccc ccgccuucaa ggugcgggag uucagcauca     1260

ccgacguggu cccguacccc aucucccugc gcuggaacag ccccgccgag gagggcucca     1320

gcgacugcga gguguucucc aagaaccacg ccgcccccuu cagcaaggug cucaccuucu     1380

accggaagga gccguucacc cuggaggcgu acuacuccag cccccaggac cugcccuacc     1440

ccgacccggc caucgcccag uucuccgucc agaaggugac gccccagagc gacgggucca     1500

gcuccaaggu gaaggucaag gugcgcguga acguccacgg caucuucagc guguccagcg     1560

ccagccucgu ggagguccac aaguccgagg agaacgagga gcccauggag accgaccaga     1620

acgccaagga ggaggagaag augcaggucg accaggagga gccccacgug gaggagcagc     1680

agcagcagac cccggcggag aacaaggccg agagcgagga gauggagacc ucccaggccg     1740

gcagcaagga caagaagaug gaccagccgc cccaggccaa gaaggccaag gugaagacgu     1800

ccaccgugga ccugcccauc gagaaccagc ugcucuggca gaucgaccgc gagaugcuga     1860

accuguacau cgagaacgag gggaagauga ucaugcagga caagcucgag aaggagcgga     1920

acgacgcgaa gaacgccgug gaggaguacg ucuacgagau gcgcgacaag cugagcggcg     1980

aguacgagaa guucgugucc gaggacgacc ggaacagcuu cacccugaag cucgaggaca     2040

ccgagaacug gcuguacgag gacggggagg accagcccaa gcaggucuac guggacaagc     2100

uggccgagcu gaagaaccuc ggccagccca ucaagauccg cuuccaggag uccgaggagc     2160

ggcccaagcu guucgaggag cuggggaagc agauccagca guacaugaag aucaucagcu     2220

ccuucaagaa caaggaggac caguacgacc accucgacgc cgcggacaug acgaaggugg     2280

agaaguccac caacgaggcc auggagugga ugaacaacaa gcugaaccug cagaacaagc     2340

agagccucac cauggacccg guggucaaga gcaaggagau cgaggccaag aucaaggagc     2400

ugaccuccac gugcagcccc aucaucucca agcccaagcc caagguggag ccgcccaagg     2460

aggagcagaa gaacgccgag cagaacggcc ccguggacgg ccagggggac aaccccggcc     2520

cgcaggccgc ggagcagggg accgacaccg ccguccccag cgacagcgac aagaagcugc     2580

ccgagaugga caucgacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  6370
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt1)

<400>  6370
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccuc aacugcuaca      120

ucgccguggc ccgcuccggc gggaucgaga ccaucgcgaa cgaguacagc gaccggugca      180

cccccgccug caucucccug ggcagccgca cgcgggccau cgggaacgcc gccaaguccc      240

agaucgugac caacguccgc aacaccaucc acggcuucaa gaagcugcac ggccggagcu      300

ucgacgaccc gaucgugcag accgagcgca uccggcuccc cuacgagcug cagaagaugc      360

ccaacggguc cgcgggcgug aagguccgcu accuggagga ggagcggccc uucgccaucg      420

agcaggucac ggggaugcuc cuggccaagc ugaaggagac cagcgagaac gcccucaaga      480

agccgguggc ggacugcgug aucuccaucc ccagcuucuu caccgacgcc gagcgccggu      540

ccgugauggc cgccgcccag guggcgggcc ugaacugccu gcgccucaug aacgagacca      600

cggccgucgc ccuggccuac gggaucuaca agcaggaccu gccgccccuc gacgagaagc      660

cccggaacgu gguguucauc gacaugggcc acagcgccua ccagguccug gugugcgcgu      720

ucaacaaggg caagcugaag gugcucgcca ccaccuucga ccccuaccuc gggggccgca      780

acuucgacga ggcccugguc gacuacuucu gcgacgaguu caagaccaag uacaagauca      840

acgugaagga gaacucccgg gcccugcugc gccuguacca ggagugcgag aagcucaaga      900

agcugaugag cgccaacgcg uccgaccugc cccucaacau cgagugcuuc augaacgacc      960

uggacgugag cuccaagaug aaccgggccc aguucgagca gcugugcgcc agccuccugg     1020

cccgcgucga gcccccgcug aaggccguga uggagcaggc gaaccuccag cgggaggaca     1080

ucuccagcau cgagaucguc gggggcgcca cgcgcauccc cgccgugaag gagcagauca     1140

ccaaguucuu ccugaaggac aucagcacca cccugaacgc cgacgaggcg guggcccggg     1200

gcugcgcccu ccagugcgcc auccuguccc ccgccuucaa gguccgcgag uucagcauca     1260

cggaccuggu gcccuacucc aucacccucc gcuggaagac cagcuucgag gacggguccg     1320

gcgagugcga gguguucugc aagaaccacc cggcgcccuu cagcaagguc aucaccuucc     1380

acaagaagga gcccuucgag cuggaggccu ucuacacgaa ccugcacgag gugcccuacc     1440

cggacgcccg gaucgggucc uucaccaucc agaacguguu cccccagagc gacggcgacu     1500

ccagcaaggu caaggugaag gugcgcguca acauccacgg gaucuucucc guggccagcg     1560

ccuccgugau cgagaagcag aaccucgagg gcgaccacag cgacgcgccc auggagaccg     1620

agaccuccuu caagaacgag aacaaggaca acauggacaa gaugcagguc gaccaggagg     1680

agggccacca gaagugccac gccgagcaca cgcccgagga ggagaucgac cacaccgggg     1740

ccaagaccaa gagcgccgug uccgacaagc aggaccggcu gaaccagacc cugaagaagg     1800

gcaaggucaa gagcaucgac cucccgaucc aguccagccu gugccgccag cuggggcagg     1860

accuccugaa cagcuacauc gagaacgagg gcaagaugau caugcaggac aagcuggaga     1920

aggagcggaa cgacgccaag aacgcggugg aggaguacgu guacgacuuc cgcgaccggc     1980

uggggacggu guacgagaag uucaucaccc ccgaggaccu cuccaagcug agcgccgucc     2040

uggaggacac cgagaacugg cucuacgagg acggcgagga ccagcccaag caggucuacg     2100

uggacaagcu gcaggagcug aagaaguacg gccagcccau ccagaugaag uacauggagc     2160

acgaggagcg cccgaaggcc cucaacgacc uggggaagaa gauccagcug gugaugaagg     2220

ugaucgaggc cuaccggaac aaggacgagc gcuacgacca ccucgacccc accgagaugg     2280

agaaggugga gaagugcauc uccgacgcga ugagcuggcu gaacuccaag augaacgccc     2340

agaacaagcu gagccucacg caggaccccg ucgugaaggu guccgagauc gucgccaaga     2400

gcaaggagcu ggacaacuuc ugcaacccga ucaucuacaa gcccaagccc aaggccgagg     2460

ugcccgagga caagccgaag gccaacuccg agcacaacgg ccccauggac gggcagagcg     2520

gcaccgagac caaguccgac agcaccaagg acuccagcca gcacacgaag uccagcgggg     2580

agauggaggu ggacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  6371
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt1)

<400>  6371
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugagcc ucguggccgc caugcugcug cuccuguccg      120

cggcccgcgc cgaggaggag gacaagaagg aggacgucgg caccguggug gggaucgacc      180

ugggcaccac guacagcugc gucggggugu ucaagaacgg ccggguggag aucaucgcca      240

acgaccaggg gaaccgcauc acccccuccu acgucgccuu caccccggag ggcgagcggc      300

ucaucggcga cgcggccaag aaccagcuga ccagcaaccc cgagaacacg guguucgacg      360

ccaagcgccu gaucgggcgg accuggaacg accccuccgu gcagcaggac aucaaguucc      420

uccccuucaa ggucguggag aagaagacca agccguacau ccagguggac aucggcgggg      480

gccagaccaa gacguucgcc cccgaggaga ucagcgcgau gguccugacc aagaugaagg      540

agaccgccga ggccuaccug gggaagaagg ugacccacgc cguggucacg gugcccgccu      600

acuucaacga cgcgcagcgc caggccacca aggacgccgg caccaucgcc ggccucaacg      660

ugaugcggau caucaacgag cccaccgccg cggccaucgc cuacgggcug gacaagcgcg      720

agggcgagaa gaacauccug gucuucgacc ucgggggcgg cacguucgac gugucccugc      780

ugaccaucga caacggggug uucgaggucg uggccaccaa cggcgacacc caccucgggg      840

gcgaggacuu cgaccagcgg gugauggagc acuucaucaa gcuguacaag aagaagacgg      900

ggaaggacgu ccgcaaggac aaccgggccg ugcagaagcu gcgccgggag gucgagaagg      960

cgaagcgcgc ccucagcucc cagcaccagg cccggaucga gaucgagagc uucuacgagg     1020

gcgaggacuu cuccgagacc cugacccgcg ccaaguucga ggagcugaac auggaccucu     1080

uccggagcac caugaagccg gugcagaagg ugcuggagga cuccgaccug aagaaguccg     1140

acaucgacga gaucguccuc gugggcggga gcacgcgcau ccccaagauc cagcagcugg     1200

ugaaggaguu cuucaacggc aaggagccca gccgggggau caaccccgac gaggccgucg     1260

cguacggcgc cgccgugcag gccggggugc uguccggcga ccaggacacc ggcgaccucg     1320

uccugcugga cgugugcccg cucacccugg ggaucgagac cgugggcggg gucaugacga     1380

agcugauccc ccgcaacacc guggugccca ccaagaaguc ccagaucuuc agcaccgcga     1440

gcgacaacca gcccacgguc accaucaagg uguacgaggg cgagcggccg cucaccaagg     1500

acaaccaccu ccuggggacc uucgaccuga cgggcauccc gcccgcgccc cgcggcgugc     1560

cccagaucga ggucaccuuc gagaucgacg ugaacgggau ccugcgcgug accgccgagg     1620

acaagggcac cgggaacaag aacaagauca ccaucacgaa cgaccagaac cggcugaccc     1680

ccgaggagau cgagcgcaug gucaacgacg ccgagaaguu cgccgaggag gacaagaagc     1740

ucaaggagcg gaucgacacc cgcaacgagc uggagagcua cgccuacucc cugaagaacc     1800

agaucggcga caaggagaag cucggcggga agcugagcuc cgaggacaag gagaccaugg     1860

agaaggccgu ggaggagaag aucgaguggc uggagagcca ccaggacgcc gacaucgagg     1920

acuucaaggc caagaagaag gagcucgagg agaucgugca gcccaucauc uccaagcugu     1980

acggcagcgc cgggcccccg cccacgggcg aggaggacac cgcggagaag gacgagcugu     2040

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  6372
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt1)

<400>  6372
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggcgcccc gcgagcuggc cgugggcauc gaccucggga      120

ccaccuacag cugcgucggc guguuccagc aggggcgggu ggagauccug gccaacgacc      180

agggcaaccg cacgaccccg uccuacgucg ccuucaccga caccgagcgg cugguggggg      240

acgccgccaa gagccaggcc gcgcucaacc cccacaacac gguguucgac gccaagcgcc      300

ugaucggccg gaaguucgcc gacaccaccg uccaguccga caugaagcac uggcccuucc      360

gcguggugag cgagggcggg aagcccaagg uccgggugug cuaccgcggc gaggacaaga      420

ccuucuaccc ggaggagauc uccagcaugg ugcuguccaa gaugaaggag acggccgagg      480

cguaccucgg gcagcccguc aagcacgccg ugaucaccgu gcccgccuac uucaacgaca      540

gccagcggca ggccaccaag gacgccggcg cgaucgccgg gcugaacguc cugcgcauca      600

ucaacgagcc caccgccgcc gccaucgcgu acggccucga ccggcgcggc gccggggagc      660

ggaacgugcu gaucuucgac cugggcgggg gcacguucga cguguccguc cucagcaucg      720

acgccggcgu guucgaggug aaggccaccg ccggggacac ccaccugggc ggggaggacu      780

ucgacaaccg ccuggucaac cacuucaugg aggaguuccg gcgcaagcac ggcaaggacc      840

ucuccgggaa caagcgggcg cugcgccggc ugcgcaccgc cugcgagcgg gccaagcgca      900

cgcucagcuc cagcacccag gccacccugg agaucgacuc ccuguucgag ggcguggacu      960

ucuacaccag caucacgcgc gcccgguucg aggagcucug cuccgaccug uuccgcagca     1020

cccuggagcc gguggagaag gcgcuccggg acgccaagcu ggacaaggcc cagauccacg     1080

acgucgugcu ggucggcggg uccacccgca uccccaaggu gcagaagcuc cugcaggacu     1140

ucuucaacgg caaggagcug aacaagagca ucaaccccga cgaggccgug gcguacgggg     1200

ccgccgucca ggccgccgug cucaugggcg acaagugcga gaaggugcag gaccugcugc     1260

uccuggacgu cgcgccccug agccucgggc uggagaccgc cggcggcgug augacgaccc     1320

ugauccagcg gaacgccacc aucccgacca agcagacgca gaccuucacc accuacuccg     1380

acaaccagcc cgggguguuc auccaggucu acgagggcga gcgcgccaug acgaaggaca     1440

acaaccuccu ggggcgguuc gagcugagcg gcaucccgcc cgcgccccgc ggggugcccc     1500

agaucgaggu gaccuucgac aucgacgcca acggcauccu cuccgucacc gccaccgacc     1560

ggagcacggg caaggccaac aagaucacca ucaccaacga caaggggcgc cuguccaagg     1620

aggaggugga gcggauggug cacgaggccg agcaguacaa ggccgaggac gaggcgcagc     1680

gcgaccgggu cgccgccaag aacagccugg aggcccacgu guuccacgug aagggcuccc     1740

uccaggagga gagccugcgc gacaagaucc ccgaggagga ccggcgcaag augcaggaca     1800

agugccggga gguccuggcg uggcucgagc acaaccagcu ggccgagaag gaggaguacg     1860

agcaccagaa gcgcgagcug gagcagaucu gccggcccau cuucucccgc cuguacgggg     1920

gcccgggcgu gcccgggggc agcuccugcg ggacccaggc ccgccagggc gaccccagca     1980

ccgggcccau caucgaggag guggacugag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  6373
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt1)

<400>  6373
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggcgcccc gcgagcuggc cgugggcauc gaccucggga      120

ccaccuacag cugcgucggc guguuccagc aggggcgggu ggagauccug gccaacgacc      180

agggcaaccg cacgaccccg uccuacgucg ccuucaccga caccgagcgg cugguggggg      240

acgccgccaa gagccaggcc gcgcucaacc cccacaacac gguguucgac gccaagcgcc      300

ugaucggccg gaaguucgcc gacaccaccg uccaguccga caugaagcac uggcccuucc      360

agguggugag cgagggcggg aagcccaagg uccgcgugug cuaccggggc gaggacaaga      420

ccuucuaccc ggaggagauc uccagcaugg ugcuguccaa gaugaaggag acggccgagg      480

cguaccucgg gcagcccguc aagcacgccg ugaucaccgu gcccaccuac uucagcaacu      540

cccagcgcca ggccaccaag gacgccggcg ccaucgcggg gcugaagguc cugcccauca      600

ucaacgaggc cacggccgcc gccaucgcgu acggccucga ccggcgcggc gccgggaagc      660

ggaacgugcu gaucuucgac cugggcgggg gcaccuucga cgugagcguc cucuccaucg      720

acgccggcgu guucgaggug aaggccaccg ccggggacac ccaccugggc ggggaggacu      780

ucgacaaccg ccuggucaac cacuucaugg aggaguuccg gcgcaagcac ggcaaggacc      840

ucagcgggaa caagcgggcg cugcgccggc ugcgcacggc cugcgagcgg gccaagcgca      900

ccccguccag cuccacccag gccacccucg agaucgacag ccuguucgag ggcguggacu      960

ucuacaaguc caucacgcgg gcccgcuucg aggagcugug cagcgaccuc uuccgcucca     1020

cccuggagcc cguggagaag gcgcugcggg acgccaagcu cgacaaggcc cagauccacg     1080

acuucguccu gggcgggggc cugcacagcc acccccaggg ggccgaggug gcggccggcc     1140

uccugcagcg ccagggggcc gagcaggagc accagcccug aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  6374
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt1)

<400>  6374
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaagggcc ccgccguggg gaucgaccug ggcaccaccu      120

acuccugcgu cgggguguuc cagcacggca agguggagau caucgccaac gaccagggga      180

accgcacgac ccccagcuac gucgcguuca ccgacaccga gcggcucauc ggcgacgccg      240

ccaagaacca gguggccaug aaccccacga acaccguguu cgacgccaag cgccugaucg      300

gccggcgcuu cgacgacgcg gucgugcagu ccgacaugaa gcacuggccc uucauggugg      360

ucaacgacgc cgggcggccc aagguccagg uggaguacaa gggcgagacc aagagcuucu      420

acccggagga gguguccagc auggugcuga ccaagaugaa ggagaucgcc gaggccuacc      480

ucgggaagac ggugaccaac gcggucguga ccgugcccgc cuacuucaac gacucccagc      540

gccaggccac caaggacgcc ggcacgaucg ccgggcugaa cguccugcgg aucaucaacg      600

agcccaccgc ggccgccauc gccuacggcc ucgacaagaa ggugggcgcc gagcgcaacg      660

ugcugaucuu cgaccucggg ggcgggaccu ucgacgucag cauccugacc aucgaggacg      720

gcaucuucga ggugaagucc acggcgggcg acacccaccu cgggggcgag gacuucgaca      780

accggauggu gaaccacuuc aucgccgagu ucaagcgcaa gcacaagaag gacaucagcg      840

agaacaagcg ggccguccgc cggcugcgca ccgccugcga gcgggccaag cgcacccugu      900

ccagcuccac gcaggcgagc aucgagaucg acucccugua cgaggggauc gacuucuaca      960

ccagcaucac ccgggcccgc uucgaggagc ugaacgccga ccucuuccgg ggcacccugg     1020

accccgugga gaaggcccug cgcgacgcca agcucgacaa gucccagauc cacgacaucg     1080

uccuggucgg gggcagcacg cggaucccga agauccagaa gcugcuccag gacuucuuca     1140

acggcaagga gcugaacaag uccaucaacc ccgacgaggc gguggccuac ggggccgccg     1200

ugcaggcggc cauccugagc ggcgacaaga gcgagaacgu gcaggaccuc cugcugcucg     1260

acgugacgcc ccugucccug gggaucgaga ccgccggcgg ggucaugacc gugcucauca     1320

agcgcaacac caccaucccc accaagcaga cccagacguu caccaccuac agcgacaacc     1380

agccgggcgu gcugauccag gucuacgagg gcgagcgcgc caugaccaag gacaacaacc     1440

ugcucgggaa guucgagcug acgggcaucc cgcccgcgcc ccgcggggug ccccagaucg     1500

aggugaccuu cgacaucgac gccaacggca uccugaacgu cuccgccgug gacaagagca     1560

ccgggaagga gaacaagauc accaucacca acgacaaggg ccggcucucc aaggaggaca     1620

ucgagcggau ggugcaggag gccgagaagu acaaggccga ggacgagaag cagcgcgaca     1680

aggucagcuc caagaacagc cuggaguccu acgccuucaa caugaaggcg acgguggagg     1740

acgagaagcu gcagggcaag aucaacgacg aggacaagca gaagauccuc gacaagugca     1800

acgagaucau caacuggcug gacaagaacc agaccgccga gaaggaggag uucgagcacc     1860

agcagaagga gcuggagaag gugugcaacc ccaucaucac caagcucuac cagagcgccg     1920

ggggcaugcc cgggggcaug cccggcgggu ucccgggcgg gggcgccccg cccuccgggg     1980

gcgccagcuc cggccccacc aucgaggagg ucgacugagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  6375
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt1)

<400>  6375
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucagcgccu cccgcgccgc ggccgcccgg cuggugggcg      120

ccgccgcgag ccgcgggccc accgccgccc ggcaccagga cuccuggaac ggccucagcc      180

acgaggccuu ccgccugguc ucccggcgcg acuacgcgag cgaggccauc aagggggccg      240

uggugggcau cgaccugggg accacgaacu ccugcgucgc cgugauggag ggcaagcagg      300

ccaaggugcu cgagaacgcg gagggcgccc ggaccacccc gagcgucgug gccuucaccg      360

ccgacgggga gcgccuggug ggcaugcccg ccaagcggca ggcggucacg aaccccaaca      420

acaccuucua cgccaccaag cgccugaucg ggcggcgcua cgacgacccc gaggugcaga      480

aggacaucaa gaacgugccg uucaagaucg uccgggccuc caacggcgac gccugggugg      540

aggcccacgg gaagcucuac agccccuccc agaucggcgc guucgugcug augaagauga      600

aggagaccgc cgagaacuac cugggccaca cggccaagaa cgccgucauc accgugcccg      660

ccuacuucaa cgacagccag cgccaggcga ccaaggacgc cgggcagauc uccggccuca      720

acgugcugcg ggucaucaac gagcccaccg ccgccgcgcu ggccuacggg cucgacaaga      780

gcgaggacaa ggugaucgcc guguacgacc ugggcggcgg gacguucgac aucuccaucc      840

uggagaucca gaagggcguc uucgagguca agagcaccaa cggggacacc uuccucggcg      900

gggaggacuu cgaccaggcc cugcugcgcc acaucgugaa ggaguucaag cgggagaccg      960

gcguggaccu cacgaaggac aacauggccc ugcagcgcgu gcgggaggcg gccgagaagg     1020

ccaagugcga gcuguccagc uccguccaga ccgacaucaa ccucccguac cugaccaugg     1080

acagcagcgg ccccaagcac cugaacauga agcucacccg cgcccaguuc gaggggaucg     1140

ugacggaccu gauccggcgc accaucgccc ccugccagaa ggcgaugcag gacgccgagg     1200

uguccaagag cgacaucggc gaggucaucc uggucggggg caugacccgc augcccaagg     1260

ugcagcagac cgugcaggac cucuucgggc gggccccguc caaggccgug aaccccgacg     1320

aggccguggc gaucggcgcc gccauccagg gcgggguccu ggccggcgac gugacggacg     1380

ugcugcuccu ggacgucacg ccccugagcc ucgggaucga gacccugggc gggguguuca     1440

ccaagcugau caaccgcaac accaccaucc ccaccaagaa gucccaggug uucagcaccg     1500

cggccgacgg ccagacgcag gucgagauca aggugugcca gggcgagcgg gagauggccg     1560

gggacaacaa gcuccugggc caguucaccc ugaucgggau cccgcccgcg ccccgcggcg     1620

ugccccagau cgaggucacc uucgacaucg acgccaacgg caucgugcac guguccgcca     1680

aggacaaggg gaccggccgg gagcagcaga ucgucaucca gagcuccggg ggccucagca     1740

aggacgacau cgagaacaug gugaagaacg ccgagaagua cgccgaggag gaccgccgga     1800

agaaggagcg cguggaggcc gucaacaugg ccgaggggau cauccacgac acggagacca     1860

agauggagga guucaaggac cagcugccgg cggacgagug caacaagcug aaggaggaga     1920

ucuccaagau gcgggagcuc cuggcccgca aggacagcga gaccggcgag aacauccggc     1980

aggccgccuc cagccugcag caggccuccc ucaagcuguu cgagauggcg uacaagaaga     2040

uggccagcga gcgcgagggc uccgggagcu ccggcaccgg ggagcagaag gaggaccaga     2100

aggaggagaa gcagugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  6376
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt1)

<400>  6376
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg aggccggcgg gagcgacggc ccccgcgaga      120

ccgcgccgac cuccgccuac agcucccccg cccggagccu gggggacacg ggcaucacgc      180

cccucucccc cagccacauc gugaacgaca ccgacuccaa cgucagcgag cagcaguccu      240

uccugguggu ggucgccgug gacuucggga ccaccagcuc cggcuacgcc uacagcuuca      300

ccaaggagcc ggagugcauc cacgugaugc gccgguggga gggcggggac cccggcgucu      360

ccaaccagaa gacccccacc acgauccugc ucacccccga gcgcaaguuc cacagcuucg      420

gguacgcggc ccgggacuuc uaccacgacc uggacccgaa cgaggccaag caguggcugu      480

accucgagaa guucaagaug aagcugcaca ccaccggcga ccugacgaug gacaccgacc      540

ucaccgccgc gaacgggaag aaggugaagg cccuggagau cuucgccuac gcccugcagu      600

acuucaagga gcaggcccuc aaggagcugu ccgaccaggc gggcagcgag uucgagaacu      660

ccgacgugcg cugggucauc accgugcccg ccaucuggaa gcagcccgcc aagcaguuca      720

ugcggcaggc cgccuaccag gcgggccugg ccagccccga gaacuccgag cagcucauca      780

ucgcccugga gccggaggcc gccagcaucu acugccgcaa gcugcggcuc caccagauga      840

ucgagcugag cuccaaggcg gccgugaacg gguacagcgg cuccgacacg gucggggccg      900

gcuucaccca ggccaaggag cacauccgcc ggaaccgcca gagccggacc uuccuggugg      960

agaacgugau cggcgagauc ugguccgagc ucgaggaggg ggacaaguac gucguggugg     1020

acagcggcgg gggcaccguc gaccugacgg ugcaccagau ccgccugccc gaggggcacc     1080

ucaaggagcu guacaaggcc accggcggcc ccuacggguc ccugggcgug gacuacgagu     1140

ucgagaagcu ccuguacaag aucuucgggg aggacuucau cgagcaguuc aagaucaagc     1200

ggcccgcggc cugggucgac cugaugaucg ccuucgagag ccgcaagcgg gccgcggccc     1260

cggaccgcac caacccccuc aacaucaccc ugcccuucuc cuucaucgac uacuacaaga     1320

aguuccgggg ccacagcgug gagcacgccc ugcgcaaguc caacguggac uucgucaagu     1380

ggagcuccca ggggaugcuc cggaugagcc ccgacgccau gaacgcccug uucaagccga     1440

cgaucgacuc caucaucgag caccuccgcg accuguucca gaagcccgag gugagcaccg     1500

ucaaguuccu guuccuggug ggcggcuucg cggaggcgcc ccuccugcag caggccgugc     1560

aggccgccuu cggggaccag ugccgcauca ucauccccca ggacgucggc cugaccaucc     1620

ucaagggggc cgugcuguuc ggccuggacc cggccgugau caagguccgg cgcagccccc     1680

ucaccuacgg ggugggcgug cugaaccggu acgucgaggg caagcacccg cccgagaagc     1740

ugcucgugaa ggacgggacg cgcuggugca ccgacguguu cgacaaguuc aucuccgccg     1800

accaguccgu cgcccugggc gagcugguga agcggagcua cacccccgcc aagcccagcc     1860

agcuggugau cgucaucaac aucuacucca gcgagcacga caacgugucc uucaucaccg     1920

accccggggu gaagaagugc ggcacgcucc gccuggaccu gaccggcacc agcgggaccg     1980

cggucccggc ccggcgcgag auccagacgc ucaugcaguu cggcgacacc gagaucaagg     2040

ccaccgccau cgacaucgcg accuccaaga gcgugaaggu ggggaucgac uuccugaacu     2100

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  6377
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt1)

<400>  6377
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuggccgugc ccgagauggg ccuccagggg cuguacaucg      120

gcagcucccc cgagcgcagc cccguccccu ccccgcccgg gagcccccgg acccaggagu      180

ccugcggcau cgccccgcug acccccagcc agucccccaa gcccgaggug cgcgcgcccc      240

agcaggccag cuucuccgug gucguggcca ucgacuucgg gacgaccagc uccggcuacg      300

ccuucagcuu cgccuccgac cccgaggcga uccacaugau gcggaagugg gagggcgggg      360

acccgggcgu ggcccaccag aagaccccga ccugccuccu gcugacgccc gagggggccu      420

uccacagcuu cggcuacacc gcccgcgacu acuaccacga ccucgacccc gaggaggcgc      480

gggacuggcu guacuucgag aaguucaaga ugaagaucca cuccgccacc gaccugaccc      540

ucaagacgca gcuggaggcc gucaacggga agaccaugcc cgcccuggag guguucgccc      600

acgcgcuccg cuucuuccgg gagcacgccc ugcaggagcu gcgcgagcag agccccuccc      660

uccccgagaa ggacaccgug cggugggucc ugaccgugcc cgccaucugg aagcagccgg      720

ccaagcaguu caugcgcgag gccgcguacc uggccggccu cgugagccgg gagaacgccg      780

agcagcugcu gaucgcccuc gagcccgagg ccgcguccgu cuacugccgc aagcugcggc      840

ugcaccagcu ccuggaccug agcggccgcg cccccggggg cgggcggcuc ggcgagcgcc      900

ggagcaucga cuccagcuuc cgccaggccc gggagcagcu gcgccggucc cgccacagcc      960

gcacguuccu gguggagucc ggcguggggg agcucugggc cgagaugcag gccggcgacc     1020

gguacgucgu ggcggacugc gggggcggga ccguggaccu gaccguccac cagcuggagc     1080

agccccacgg cacccucaag gagcuguaca aggccagcgg cgggccguac ggcgccgugg     1140

ggguggaccu ggccuucgag cagcuccugu gccgcaucuu cggcgaggac uucaucgcga     1200

cguucaagcg gcagcgcccc gccgccuggg ucgaccugac caucgccuuc gaggcccgga     1260

agcgcaccgc ggggccccac cgggccggcg cccucaacau cucccugccc uucagcuuca     1320

ucgacuucua ccgcaagcag cggggccaca acguggagac cgcccugcgc cgguccagcg     1380

ugaacuucgu caaguggucc agccagggga ugcuccgcau guccugcgag gccaugaacg     1440

agcuguucca gccgacggug agcggcauca uccagcacau cgaggcgcug cucgcccggc     1500

ccgaggucca gggggugaag cugcuguucc ucgugggcgg guucgccgag uccgccgucc     1560

ugcagcacgc cgugcaggcg gcccugggcg cccgcggccu gcgggugguc gugccccacg     1620

acguggggcu caccauccug aagggcgccg uccuguucgg gcaggcgccg ggcguggugc     1680

gcguccggcg cagcccccuc accuacggcg ugggggugcu gaaccgguuc guccccggcc     1740

gccacccgcc cgagaagcug cucgugcgcg acgggcggcg cuggugcacc gacguguucg     1800

agcgguucgu cgccgccgag caguccgugg cccugggcga ggaggugcgc cggagcuacu     1860

gccccgcccg ccccgggcag cggcgcgucc ugaucaaccu cuacugcugc gcggccgagg     1920

acgcccgguu caucacggac cccggcgugc gcaagugcgg cgcccugucc cuggagcucg     1980

agccggccga cugcgggcag gacaccgcgg gcgccccgcc cgggcggcgc gagauccggg     2040

ccgccaugca guucggcgac accgagauca aggugaccgc cgucgacgug agcacgaacc     2100

gcagcgugcg ggcguccauc gacuuccuga gcaacugagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  6378
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt1)

<400>  6378
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgggaga ugaccauccu gggcagcgcc gugcucaccc      120

ugcugcucgc gggguaccug gcccagcagu accugccccu cccgacgccc aaggucaucg      180

gcaucgaccu ggggaccacc uacugcuccg ugggcguguu cuuccccggg accggcaagg      240

ucaaggugau ccccgacgag aacggccaca ucagcauccc guccauggug agcuucacgg      300

acaacgacgu cuacgugggg uacgaguccg uggagcuggc cgacagcaac ccccagaaca      360

ccaucuacga cgccaagcgg uucaucggca agaucuucac cgccgaggag cucgaggcgg      420

agaucgggcg cuaccccuuc aagguccuga acaagaacgg caugguggag uucuccguga      480

ccagcaacga gacgaucacc gucucccccg aguacguggg gagccggcug cuccugaagc      540

ugaaggagau ggccgaggcc uaccucggca ugccgguggc caacgcgguc aucuccgugc      600

ccgccgaguu cgaccugaag cagcgcaaca gcaccaucga ggccgccaac cuggccggcc      660

ucaagauccu gcgggugauc aacgagccca ccgcggccgc cauggccuac gggcugcaca      720

aggccgacgu cuuccacgug cucgugaucg accugggcgg gggcacgcug gacgucuccc      780

uccugaacaa gcagggcggg auguuccuga cccgcgcgau gagcggcaac aacaagcucg      840

ggggccagga cuucaaccag cggcugcugc aguaccucua caagcagauc uaccagaccu      900

acggguucgu gcccucccgc aaggaggaga uccaccggcu gcgccaggcc guggagaugg      960

ucaagcugaa ccucacccug caccagagcg cccagcuguc cgugcuccug acggucgagg     1020

agcaggaccg gaaggagccg cacagcuccg acaccgagcu gcccaaggac aagcucagca     1080

gcgccgacga ccaccgcgug aacuccggcu ucggccgggg gcugagcgac aagaaguccg     1140

gcgagagcca ggugcuguuc gagaccgaga ucucccgcaa gcuguucgac acccugaacg     1200

aggaccuguu ccagaagauc cucgucccca uccagcaggu ccugaaggag gggcaccugg     1260

agaagacgga gaucgacgag guggugcucg ugggcgggag cacccggauc ccccgcaucc     1320

gccaggugau ccaggaguuc uucggcaagg acccgaacac cuccgucgac cccgaccugg     1380

ccguggugac cggcgucgcg auccaggccg ggaucgacgg cgggagcugg ccccuccagg     1440

uguccgcccu ggagaucccc aacaagcacc uccagaagac gaacuucaac ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6379
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt1)

<400>  6379
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgccaucg gcgugcaccu ggggugcacc agcgcgugcg      120

ucgccgugua caaggacggc cgcgccgggg uggucgccaa cgacgccggc gaccggguga      180

cccccgcggu ggucgccuac uccgagaacg aggagaucgu ggggcucgcc gccaagcaga      240

gccgcauccg gaacaucucc aacacgguga ugaaggucaa gcagauccug ggccgcagcu      300

ccagcgaccc gcaggcgcag aaguacaucg ccgaguccaa gugccuggug aucgagaaga      360

acggcaagcu ccgguacgag aucgacaccg gggaggagac caaguucgug aaccccgagg      420

acgucgcccg ccugaucuuc agcaagauga aggagaccgc ccacuccgug cugggcagcg      480

acgccaacga cguggucauc acggugcccu ucgacuucgg ggagaagcag aagaacgcgc      540

ucggcgaggc cgcccgggcc gccggguuca acgugcugcg ccugauccac gagcccuccg      600

cggcccuccu ggccuacggc aucggccagg acagcccgac cgggaagucc aacauccugg      660

ucuucaagcu cggcgggacc agccuguccc ugagcgugau ggaggugaac uccggcaucu      720

accggguccu cagcaccaac acggacgaca acaucggcgg ggcccacuuc accgagaccc      780

uggcccagua ccuggcgucc gaguuccagc gcagcuucaa gcacgacgug cggggcaacg      840

cccgcgccau gaugaagcuc accaacagcg ccgagguggc caagcacucc cugagcacgc      900

ugggguccgc gaacugcuuc cucgacagcc uguacgaggg ccaggacuuc gacugcaacg      960

ucucccgggc ccgcuucgag cugcucugca gcccccuguu caacaagugc aucgaggcca     1020

uccgggggcu gcucgaccag aacggcuuca ccgccgacga caucaacaag gugguccugu     1080

gcggcggguc cagccgcauc cccaagcugc agcagcucau caaggaccug uuccccgcgg     1140

uggagcugcu caacuccauc ccgcccgacg aggugauccc caucggcgcc gccaucgagg     1200

ccgggauccu gaucggcaag gagaaccugc ucgucgagga cagccugaug aucgagugcu     1260

ccgcccggga cauccuggug aagggggugg acgagagcgg cgcgucccgc uucaccgucc     1320

ucuuccccag cggcaccccg cugcccgccc ggcgccagca cacgcugcag gcccccgggu     1380

ccaucagcuc cgugugccuc gagcuguacg agagcgacgg caagaacucc gccaaggagg     1440

agaccaaguu cgcccaggug guccugcagg accucgacaa gaaggagaac gggcugcggg     1500

acauccuggc ggugcucacc augaagcgcg acggcagccu gcacgugacc ugcacggacc     1560

aggagaccgg gaagugcgag gccaucagca ucgagaucgc cuccugagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  6380
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt1)

<400>  6380
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gccuggacgu ggggucccag agcugcuaca      120

ucgccguggc ccgcgcgggc gggaucgaga ccaucgccaa cgaguucucc gaccggugca      180

cccccagcgu caucuccuuc ggcagcaaga accgcaccau cgggguggcc gccaagaacc      240

agcagaucac ccacgccaac aacaccgugu ccaacuucaa gcgguuccac ggccgcgcgu      300

ucaacgaccc guucauccag aaggagaagg agaaccucag cuacgaccug gucccccuga      360

agaacggcgg ggugggcauc aaggugaugu acauggggga ggagcaccuc uucuccgucg      420

agcagaucac cgccaugcug cugacgaagc ucaaggagac cgccgagaac agccugaaga      480

agcccgugac cgacugcgug aucuccgucc ccagcuucuu caccgacgcc gagcggcgcu      540

ccgugcugga cgcggcccag aucgugggcc ucaacugccu gcggcugaug aacgacauga      600

cggccgucgc ccucaacuac gggaucuaca agcaggaccu gccgagccug gacgagaagc      660

cccgcaucgu gguguucguc gacaugggcc acuccgccuu ccaggugagc gcgugcgccu      720

ucaacaaggg caagcucaag gugcugggga ccgccuucga ccccuuccug ggcgggaaga      780

acuucgacga gaagcucguc gagcacuucu gcgccgaguu caagaccaag uacaagcugg      840

acgccaaguc caagauccgg gcgcugcucc gccuguacca ggagugcgag aagcugaaga      900

agcucaugag cuccaacagc accgaccugc cccugaacau cgagugcuuc augaacgaca      960

aggacgugag cggcaagaug aaccgguccc aguucgagga gcucugcgcc gagcugcugc     1020

agaagaucga ggugccgcuc uacagccugc uggagcagac gcaccucaag gucgaggacg     1080

uguccgccgu cgagaucgug ggcggggcca cccgcauccc cgccgugaag gagcggaucg     1140

cgaaguucuu cggcaaggac aucagcacca cccugaacgc cgacgaggcc gucgcccgcg     1200

ggugcgcccu gcagugcgcg auccucuccc ccgccuucaa ggugcgggag uucagcguga     1260

cggacgccgu ccccuucccg aucucccuga ucuggaacca cgacagcgag gacaccgagg     1320

gcgugcacga gguguucucc cgcaaccacg ccgcgcccuu cagcaagguc cugaccuucc     1380

uccggcgcgg gcccuucgag cuggaggccu ucuacuccga cccccagggc gugccguacc     1440

ccgaggccaa gaucggccgg uucguggucc agaacgugag cgcccagaag gacggggaga     1500

agucccgcgu gaaggucaag gugcggguga acacccacgg caucuucacg aucagcaccg     1560

ccuccauggu cgagaaggug cccaccgagg agaacgagau gagcuccgag gcggacaugg     1620

agugccugaa ccagcggccc ccggagaacc ccgacaccga caagaacgug cagcaggaca     1680

acagcgaggc cgggacgcag ccccaggucc agaccgacgc ccagcagacc ucccagagcc     1740

cgcccagccc cgagcucacc uccgaggaga acaagauccc cgacgccgac aaggccaacg     1800

agaagaaggu ggaccagccc ccggaggcga agaagcccaa gaucaaggug gucaacgugg     1860

agcugcccau cgaggccaac cugguguggc agcucggcaa ggaccugcug aacauguaca     1920

ucgagacgga ggggaagaug aucaugcagg acaagcucga gaaggagcgc aacgacgcca     1980

agaacgccgu cgaggaguac guguacgagu uccgcgacaa gcugugcggc ccguacgaga     2040

aguucaucug cgagcaggac caccagaacu uccugcgccu gcucaccgag accgaggacu     2100

ggcuguacga ggagggcgag gaccaggcca agcaggcgua cguggacaag cuggaggagc     2160

ucaugaagau cgggaccccc gucaaggugc gguuccagga ggccgaggag cgccccaaga     2220

uguucgagga gcugggccag cggcugcagc acuacgccaa gaucgccgcg gacuuccgca     2280

acaaggacga gaaguacaac cacaucgacg agagcgagau gaagaaggug gagaaguccg     2340

ucaacgaggu gauggagugg augaacaacg ugaugaacgc ccaggccaag aagucccucg     2400

accaggaccc cgucgugcgg gcccaggaga ucaagacgaa gaucaaggag cugaacaaca     2460

cgugcgagcc gguggucacc cagcccaagc ccaagaucga gagccccaag cuggagcgca     2520

ccccgaacgg gcccaacauc gacaagaagg aggaggaccu cgaggacaag aacaacuucg     2580

gcgccgagcc gccccaccag aacggggagu gcuaccccaa cgagaagaac agcgugaaca     2640

uggaccugga cugaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  6381
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt1)

<400>  6381
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg ugcgccggca gcgcccccgg cgccgggucu      120

gcugggcccu gguggcggug cuccuggccg accugcucgc ccugagcgac acccuggccg      180

ucauguccgu ggaccucggc agcgagucca ugaagguggc caucgucaag ccgggggugc      240

ccauggagau cgugcugaac aaggagagcc gccggaagac ccccgucauc gugacgcuga      300

aggagaacga gcgcuucuuc ggcgacuccg cggccagcau ggccaucaag aaccccaagg      360

ccacccuccg guacuuccag caccuccugg ggaagcaggc ggacaacccg cacguggccc      420

uguaccaggc ccgcuucccc gagcacgagc ugaccuucga cccccagcgg cagaccgucc      480

acuuccagau cuccagccag cugcaguucu cccccgagga ggugcucggc auggugcuga      540

acuacagccg cucccuggcc gaggacuucg ccgagcagcc gaucaaggac gcggucauca      600

cggugcccgu guucuucaac caggccgagc ggcgcgccgu ccuccaggcc gcccggaugg      660

cggggcugaa ggugcugcag cucaucaacg acaacaccgc caccgcccug agcuacggcg      720

uguuccgccg gaaggacauc aacaccacgg cccagaacau cauguucuac gacaugggcu      780

ccgggagcac cgucugcacc aucgugaccu accagauggu gaagacgaag gaggccggca      840

ugcagcccca gcugcagauc cgcggggucg gcuucgaccg gacccucggg ggccuggaga      900

uggagcugcg ccuccgggag cgccuggcgg gccuguucaa cgagcagcgc aaggggcagc      960

gggccaagga cgugcgcgag aacccccggg ccauggccaa gcuccugcgc gaggccaacc     1020

ggcugaagac cguccucucc gcgaacgccg accacauggc ccagaucgag ggccugaugg     1080

acgacgugga cuucaaggcc aaggugaccc gcgucgaguu cgaggagcug ugcgcggacc     1140

ucuucgagcg ggugccgggg cccgugcagc aggcccugca gagcgccgag augucccugg     1200

acgagaucga gcaggucauc cucgugggcg gcgccacgcg cgugccccgg guccaggagg     1260

ugcugcugaa ggccgugggg aaggaggagc ucggcaagaa caucaacgcg gacgaggccg     1320

ccgccauggg ggccgucuac caggcggccg cccugagcaa ggccuucaag gugaagcccu     1380

ucgugguccg cgacgccgug guguacccga uccuggucga guucacccgg gagguggagg     1440

aggagcccgg cauccacucc cucaagcaca acaagcgcgu gcuguucagc cggauggggc     1500

ccuaccccca gcgcaagguc aucaccuuca accgguacag ccacgacuuc aacuuccaca     1560

ucaacuacgg cgaccugggc uuccucgggc cggaggaccu gcgcguguuc ggcucccaga     1620

accugaccac ggugaagcug aagggggucg gcgacagcuu caagaaguac cccgacuacg     1680

aguccaaggg gaucaaggcg cacuucaacc ucgacgagag cggcgugcug ucccuggacc     1740

ggguggagag cgucuucgag acccucgugg aggacuccgc cgaggaggag agcacccuga     1800

ccaagcuggg caacacgauc uccagccucu ucgggggcgg gaccaccccc gacgccaagg     1860

agaacggcac cgacacggug caggaggagg aggagucccc cgccgagggg agcaaggacg     1920

agccgggcga gcaggucgag cugaaggagg aggcggaggc ccccguggag gacggcuccc     1980

agccgccgcc gcccgagccc aagggggacg ccacccccga gggcgagaag gccaccgaga     2040

aggagaacgg ggacaagagc gaggcccaga agcccuccga gaaggcggag gccggccccg     2100

agggcguggc ccccgccccc gagggggaga agaagcagaa gcccgcccgc aagcggcgca     2160

uggucgagga gaucggcgug gagcuggugg uccucgaccu gcccgaccug cccgaggaca     2220

agcucgcgca gagcgugcag aagcugcagg accugacccu ccgcgaccug gagaagcagg     2280

agcgggagaa ggccgccaac ucccuggagg ccuucaucuu cgagacgcag gacaagcucu     2340

accagccgga guaccaggag gugagcaccg aggagcagcg cgaggagauc uccgggaagc     2400

ugagcgccgc gagcaccugg cuggaggacg agggcgucgg ggccaccacg gugaugcuca     2460

aggagaagcu ggccgagcug cggaagcucu gccagggccu guucuuccgc guggaggagc     2520

ggaagaagug gcccgagcgc cuguccgccc ucgacaaccu gcugaaccac agcuccaugu     2580

uccucaaggg cgcgcggcug auccccgaga uggaccagau cuucaccgag gucgagauga     2640

ccacccugga gaaggugauc aacgagaccu gggccuggaa gaacgccacg cucgccgagc     2700

aggccaagcu gcccgcgacc gagaagccgg ugcugcucag caaggacauc gaggccaaga     2760

ugauggcccu ggaccgcgag guccaguacc ugcucaacaa ggccaaguuc accaagcccc     2820

ggccccgccc caaggacaag aacgggaccc gggccgagcc gccccugaac gcguccgcca     2880

gcgaccaggg cgagaaggug aucccgcccg ccgggcagac ggaggacgcc gagcccaucu     2940

ccgagcccga gaagguggag accggcagcg agcccgggga caccgagccc cuggagcucg     3000

gcggcccggg ggccgagccc gagcagaagg agcaguccac cggccagaag cgcccccuga     3060

agaacgacga gcugugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6382
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt1)

<400>  6382
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaga cccagaccca ggaccagccc auggaggagg      120

aggaggugga gacguucgcc uuccaggccg agaucgcgca gcugaugagc cucaucauca      180

acaccuucua cuccaacaag gagaucuucc ugcgcgagcu gaucagcaac uccagcgacg      240

cccucgacaa gauccgguac gagucccuga ccgaccccag caagcuggac uccggcaagg      300

agcuccacau caaccugauc cccaacaagc aggaccgcac ccugacgauc gucgacaccg      360

ggaucggcau gaccaaggcc gaccucauca acaaccuggg gaccaucgcc aagagcggca      420

cgaaggccuu cauggaggcg cugcaggccg gggccgacau cuccaugauc ggccaguucg      480

gcgugggguu cuacagcgcc uaccucgugg cggagaaggu caccgugauc accaagcaca      540

acgacgacga gcaguacgcc ugggagucca gcgccggcgg guccuucacc gugcggacgg      600

acaccggcga gcccaugggg cgcggcacca aggucauccu gcaccugaag gaggaccaga      660

ccgaguaccu cgaggagcgg cgcaucaagg agaucgugaa gaagcacagc caguucaucg      720

gcuacccgau cacgcuguuc guggagaagg agcgggacaa ggaggucucc gacgacgagg      780

ccgaggagaa ggaggacaag gaggaggaga aggagaagga ggagaaggag agcgaggaca      840

agcccgagau cgaggacgug ggguccgacg aggaggagga gaagaaggac ggcgacaaga      900

agaagaagaa gaagaucaag gagaaguaca ucgaccagga ggagcugaac aagaccaagc      960

ccaucuggac ccgcaacccc gacgacauca ccaacgagga guacggggag uucuacaaga     1020

gccucacgaa cgacugggag gaccaccugg ccgugaagca cuucuccguc gagggccagc     1080

uggaguuccg ggcgcuccug uucgugccgc gccgggcccc cuucgaccug uucgagaacc     1140

gcaagaagaa gaacaacauc aagcucuacg ugcggcgcgu cuucaucaug gacaacugcg     1200

aggagcugau ccccgaguac cugaacuuca uccggggcgu gguggacagc gaggaccucc     1260

cccugaacau cagccgcgag augcugcagc aguccaagau ccucaagguc auccggaaga     1320

accuggugaa gaagugccug gagcuguuca ccgagcucgc cgaggacaag gagaacuaca     1380

agaaguucua cgagcaguuc agcaagaaca ucaagcuggg gauccacgag gacucccaga     1440

accgcaagaa gcucagcgag cugcugcggu acuacaccuc cgccagcggc gacgagaugg     1500

ugucccucaa ggacuacugc acccgcauga aggagaacca gaagcacauc uacuacauca     1560

cgggggagac caaggaccag gucgccaaca gcgcguucgu ggagcggcug cgcaagcacg     1620

gccuggaggu gaucuacaug aucgagccga ucgacgagua cugcguccag cagcucaagg     1680

aguucgaggg gaagacccug guguccguca ccaaggaggg ccuggagcuc cccgaggacg     1740

aggaggagaa gaagaagcag gaggagaaga agacgaaguu cgagaaccug ugcaagauca     1800

ugaaggacau ccuggagaag aagguggaga agguggucgu gagcaaccgc cucgugaccu     1860

cccccugcug caucgucacc agcaccuacg gcuggacggc caacauggag cggaucauga     1920

aggcccaggc ccugcgcgac aacuccacca ugggguacau ggccgcgaag aagcaccugg     1980

agaucaaccc cgaccacagc aucaucgaga cccugcggca gaaggccgag gccgacaaga     2040

acgacaaguc cgugaaggac cucgugaucc ugcuguacga gaccgcccuc cugagcuccg     2100

gcuucagccu ggaggacccg cagacgcacg ccaaccgcau cuaccggaug aucaagcucg     2160

ggcugggcau cgacgaggac gaccccaccg cggacgacac cuccgccgcc gucaccgagg     2220

agaugccgcc ccuggagggg gacgacgaca ccagccgcau ggaggaggug gacugaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  6383
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt1)

<400>  6383
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucca agcuggacag cggcaagggg cuccacauca      120

accuggugcc caacaagcag aaccagaccc ugaccaucgu cgacacgcgc aucggcauga      180

ccaagaccga ccucaucaac aaccugggga ccgugacgaa guccggcacc aaggccuuca      240

uggaggcccu gcaggcggac gccgacauca gcaugaucgg gcacuucggc gugggcuucu      300

acuccgccua ccucgucgcc aagaagguga ccgugaucag caagcacaac aacgacgagc      360

aguacaccug ggaguccagc gccgggggcu ccuucacggu ccggaccgac gagugaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  6384
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt1)

<400>  6384
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggagg ugcaccacgg cgaggaggag gucgagaccu      120

ucgccuucca ggccgagauc gcgcagcuga ugagccucau caucaacacc uucuacucca      180

acaaggagau cuuccugcgc gagcugauca gcaacgccuc cgacgcccuc gacaagaucc      240

gguacgagag ccugacggac ccguccaagc uggacagcgg gaaggagcuc aagaucgaca      300

ucauccccaa cccccaggag cgcacccuga cccuggugga caccggcauc gggaugacga      360

aggccgaccu caucaacaac cugggcacca ucgccaaguc cgggaccaag gcguucaugg      420

aggcccugca ggccggcgcc gacaucagca ugaucggcca guucggggug ggcuucuacu      480

ccgcguaccu cgucgccgag aagguggugg ucaucaccaa gcacaacgac gacgagcagu      540

acgccuggga gagcuccgcc gggggcagcu ucacggugcg ggccgaccac ggggagccca      600

ucggccgcgg caccaaggug auccugcacc ugaaggagga ccagaccgag uaccucgagg      660

agcggcgcgu caaggaggug gugaagaagc acucccaguu caucggguac ccgaucaccc      720

uguaccugga gaaggagcgg gagaaggaga ucagcgacga cgaggcggag gaggagaagg      780

gcgagaagga ggaggaggac aaggacgacg aggagaagcc caagaucgag gacgucgggu      840

ccgacgagga ggacgacagc ggcaaggaca agaagaagaa gacgaagaag aucaaggaga      900

aguacaucga ccaggaggag cucaacaaga ccaagcccau cuggacccgc aaccccgacg      960

acaucaccca ggaggaguac ggcgaguucu acaagucccu gacgaacgac ugggaggacc     1020

accuggccgu gaagcacuuc agcguggagg ggcagcucga guuccgggcc cugcuguuca     1080

ucccgcgccg ggcccccuuc gaccucuucg agaacaagaa gaagaagaac aacaucaagc     1140

uguacguccg ccggguguuc aucauggacu ccugcgacga gcugaucccc gaguaccuca     1200

acuucauccg cggcgugguc gacagcgagg accugccccu gaacaucagc cgggagaugc     1260

uccagcaguc caagauccug aaggugaucc gcaagaacau cgugaagaag ugccuggagc     1320

uguucagcga gcucgccgag gacaaggaga acuacaagaa guucuacgag gcguucucca     1380

agaaccugaa gcucgggauc cacgaggaca gcaccaaccg gcgccggcug uccgagcugc     1440

uccgcuacca caccagccag uccggcgacg agaugaccag ccuguccgag uacgucagcc     1500

ggaugaagga gacgcagaag uccaucuacu acaucaccgg ggagagcaag gagcaggucg     1560

ccaacuccgc cuucguggag cgcgugcgca agcggggcuu cgaggugguc uacaugaccg     1620

agccgaucga cgaguacugc gugcagcagc ugaaggaguu cgacggcaag agccucgugu     1680

ccgucaccaa ggaggggcug gagcugcccg aggacgagga ggagaagaag aagauggagg     1740

agagcaaggc caaguucgag aaccucugca agcugaugaa ggagauccug gacaagaagg     1800

uggagaaggu gacgaucucc aaccgccucg ucagcucccc cugcugcauc gugaccagca     1860

ccuacggcug gaccgccaac auggagcgga ucaugaaggc gcaggcccug cgcgacaaca     1920

gcacgauggg guacaugaug gccaagaagc accuggagau caaccccgac cacccgaucg     1980

uggagacccu gcggcagaag gccgaggccg acaagaacga caaggcgguc aaggaccucg     2040

uggugcugcu guucgagacc gcccuccugu ccagcggcuu cucccuggag gacccccaga     2100

cccacagcaa ccgcaucuac cggaugauca agcucgggcu gggcaucgac gaggacgagg     2160

ucgccgccga ggagcccaac gcggccgugc ccgacgagau cccgccccug gagggcgacg     2220

aggacgccuc ccgcauggag gagguggacu gaggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  6385
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt1)

<400>  6385
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcgcccugu gggugcucgg ccugugcugc guccugcuca      120

ccuucgggag cgugcgggcc gacgacgagg uggacgucga cggcaccgug gaggaggacc      180

uggggaaguc ccgcgagggc agccggacgg acgacgaggu gguccagcgc gaggaggagg      240

cgauccagcu ggacgggcuc aacgccuccc agauccggga gcugcgcgag aaguccgaga      300

aguucgccuu ccaggccgag gugaaccgga ugaugaagcu gaucaucaac agccucuaca      360

agaacaagga gaucuuccug cgcgagcuga ucagcaacgc cuccgacgcg cucgacaaga      420

uccggcugau cagccugacc gacgagaacg cccucuccgg caacgaggag cugaccguga      480

agaucaagug cgacaaggag aagaaccugc uccacgucac cgacacgggc guggggauga      540

cccgcgagga gcuggugaag aaccugggca ccaucgccaa gagcgggacc uccgaguucc      600

ucaacaagau gacggaggcc caggaggacg gccagagcac cuccgagcug aucgggcagu      660

ucggcgucgg cuucuacagc gcguuccugg uggccgacaa ggugaucguc accuccaagc      720

acaacaacga cacccagcac aucugggaga gcgacuccaa cgaguucagc gugaucgccg      780

acccccgggg gaacacgcuc ggccgcggga ccaccaucac ccuggugcug aaggaggagg      840

ccuccgacua ccucgagcug gacacgauca agaaccuggu caagaaguac agccaguuca      900

ucaacuuccc gaucuacgug uggagcucca agaccgagac cguggaggag cccauggagg      960

aggaggaggc cgcgaaggag gagaaggagg agagcgacga cgaggccgcc gucgaggagg     1020

aggaggagga gaagaagccc aagaccaaga agguggagaa gacggugugg gacugggagc     1080

ucaugaacga caucaagccc aucuggcagc ggccguccaa ggaggucgag gaggacgagu     1140

acaaggccuu cuacaagagc uucuccaagg agagcgacga ccccauggcc uacauccacu     1200

ucaccgcgga gggcgaggug accuucaagu ccauccuguu cguccccacc agcgcgcccc     1260

gcggccuguu cgacgaguac ggguccaaga aguccgacua caucaagcuc uacgugcggc     1320

gcguguucau cacggacgac uuccacgaca ugaugccgaa guaccugaac uucgucaagg     1380

gcguggugga cagcgacgac cugccccuca acgucagccg ggagacccug cagcagcaca     1440

agcugcucaa ggugauccgc aagaagcugg ugcggaagac ccuggacaug aucaagaaga     1500

ucgccgacga caaguacaac gacaccuucu ggaaggaguu cgggacgaac aucaagcucg     1560

gcgucaucga ggaccacucc aaccgcaccc ggcuggccaa gcugcuccgc uuccagagcu     1620

cccaccaccc caccgacauc accagccugg accaguacgu ggagcgcaug aaggagaagc     1680

aggacaagau cuacuucaug gccgggucca gccggaagga ggccgagucc agccccuucg     1740

uggagcgccu gcucaagaag ggcuacgagg ucaucuaccu gacggagccg guggacgagu     1800

acugcaucca ggcccugccc gaguucgacg gcaagcgguu ccagaacgug gccaaggagg     1860

gggucaaguu cgacgagagc gagaagacca aggagucccg cgaggccgug gagaaggagu     1920

ucgagccccu gcucaacugg augaaggaca aggcccugaa ggacaagauc gagaaggcgg     1980

uggucagcca gcggcugacc gagucccccu gcgcccucgu ggccagccag uacggcuggu     2040

ccgggaacau ggagcgcauc augaaggccc aggcguacca gaccggcaag gacaucagca     2100

cgaacuacua cgccucccag aagaagaccu ucgagaucaa cccgcggcac ccccugaucc     2160

gcgacaugcu gcggcgcauc aaggaggacg aggacgacaa gaccgugcuc gaccuggccg     2220

ucgugcuguu cgagaccgcc acccuccgga gcggguaccu gcugcccgac acgaaggccu     2280

acggcgaccg caucgagcgg augcuccgcc ugucccugaa caucgacccc gacgcgaagg     2340

uggaggagga gccggaggag gagcccgagg agaccgccga ggacaccacc gaggacacgg     2400

agcaggacga ggacgaggag auggacgucg gcaccgacga ggaggaggag accgccaagg     2460

agagcaccgc cgagaaggac gagcucugag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  6386
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt1)

<400>  6386
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgcgagc ugcgggcccu ccugcugugg ggccgccggc      120

uccgcccccu gcugcgggcg ccggcccucg ccgccgugcc cgggggcaag cccauccugu      180

gcccccgccg gaccaccgcc cagcuggggc cgcgccggaa ccccgcgugg agccuccagg      240

ccggccgccu guucuccacg cagaccgccg aggacaagga ggagccccug cacagcauca      300

ucuccagcac cgaguccguc caggggagca ccuccaagca cgaguuccag gccgagacga      360

agaagcuccu ggacaucgug gcgcggagcc uguacuccga gaaggaggug uucauccgcg      420

agcucaucag caacgccucc gacgcccugg agaagcugcg gcacaagcuc gucagcgacg      480

gccaggcccu gcccgagaug gagauccacc uccagaccaa cgccgagaag ggcaccauca      540

ccauccagga cacggggauc ggcaugaccc aggaggagcu gguguccaac cuggggacca      600

ucgcgcgcag cggcuccaag gccuuccugg acgcccucca gaaccaggcc gaggccagcu      660

ccaagaucau cgggcaguuc ggcgugggcu ucuacagcgc guucaugguc gccgaccggg      720

uggaggugua cucccgcagc gccgccccgg ggagccuggg cuaccagugg cuguccgacg      780

ggagcggcgu cuucgagauc gccgaggcgu ccggcgugcg gaccgggacg aagaucauca      840

uccaccucaa gagcgacugc aaggaguucu ccagcgaggc ccgcgugcgg gacgucguga      900

ccaaguacuc caacuucgug agcuuccccc uguaccugaa cggccgccgg augaacaccc      960

uccaggccau cuggaugaug gaccccaagg acguccgcga guggcagcac gaggaguucu     1020

accgcuacgu ggcccaggcc cacgacaagc cccgguacac ccugcacuac aagacggacg     1080

cgccgcugaa cauccgcucc aucuucuacg ugcccgacau gaagcccagc auguucgacg     1140

ucucccggga gcucgggagc uccguggccc uguacagccg caaggugcug auccagacca     1200

aggccaccga cauccucccc aaguggcugc gguucauccg cggcgucgug gacuccgagg     1260

acaucccgcu gaaccucagc cgggagcugc ugcaggaguc cgcccucauc cgcaagcugc     1320

gggacgugcu gcagcagcgc cucaucaagu ucuucaucga ccagagcaag aaggacgcgg     1380

agaaguacgc caaguucuuc gaggacuacg ggcuguucau gcgggagggc aucgucaccg     1440

ccacggagca ggaggugaag gaggacaucg ccaagcugcu ccgcuacgag uccagcgccc     1500

ugcccagcgg ccagcugacc ucccugagcg aguacgcguc ccggaugcgc gccgggaccc     1560

ggaacaucua cuaccucugc gcccccaacc gccaccuggc cgagcacagc cccuacuacg     1620

aggccaugaa gaagaaggac accgaggucc uguucugcuu cgagcaguuc gacgagcuca     1680

cgcugcugca ccuccgggag uucgacaaga agaagcugau cuccguggag accgacaucg     1740

uggucgacca cuacaaggag gagaaguucg aggaccgcag cccggcggcc gagugccugu     1800

ccgagaagga gaccgaggag cucauggccu ggaugcggaa cgugcugggc agccgcguga     1860

ccaacgucaa ggugacgcug cgccucgaca cccaccccgc cauggugacc guccuggaga     1920

ugggggccgc gcggcacuuc cugcgcaugc agcagcucgc caagacccag gaggagcggg     1980

cccagcugcu gcagcccacg cucgagauca acccccgcca cgcccugauc aagaagcuga     2040

accagcuccg ggcguccgag ccgggccugg cccagcugcu cguggaccag aucuacgaga     2100

acgccaugau cgccgccggg cugguggacg acccccgcgc gauggucggc cggcugaacg     2160

agcuccuggu gaaggcccug gagcgccacu gaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  6387
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt1)

<400>  6387
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagauca gcucccugcc cacccagcug uucaagugcu      120

gcuucugcga cuuccucaag gugaagaugc acaccaugag cuccagccac cuguucuacc      180

ucgcccugug ccugcucacg uucaccucca gcgccaccgc ggggccggag acccugugcg      240

gcgccgagcu ggucgacgcc cuccaguucg ugugcgggga ccgcggcuuc uacuucaaca      300

agcccacggg guacggcucc agcucccggc gcgcgcccca gaccggcauc guggacgagu      360

gcugcuuccg gagcugcgac cugcgccggc uggagaugua cugcgcgccc cucaagccgg      420

ccaaguccgc ccgcagcguc cgggcccagc gccacaccga caugcccaag acccagaagg      480

aggugcaccu gaagaacgcc ucccggggga gcgccggcaa caagaacuac cgcaugugag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  6388
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt1)

<400>  6388
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca uggggaaguc caugcuggug cuccugaccu      120

uccuggccuu cgccagcugc ugcaucgcgg ccuaccgccc gagcgagacc cucugcggcg      180

gggagcuggu cgacacgcug caguucgugu gcggcgaccg gggguucuac uucucccgcc      240

ccgccagccg ggugucccgc cggagccgcg gcaucgucga ggagugcugc uuccgguccu      300

gcgaccucgc ccugcuggag accuacugcg ccacccccgc caagagcgag cgcgacgugu      360

ccacgccccc gaccgugcuc cccgacaacu ucccccggua ccccgucggc aaguucuucc      420

aguacgacac cuggaagcag agcacccagc gccugcggcg cgggcugccg gcgcuccugc      480

gggcccgccg gggccacgug cuggccaagg agcucgaggc guuccgcgag gccaagcggc      540

accgcccccu gaucgcccug cccacccagg accccgccca cgggggcgcc ccgcccgaga      600

uggcguccaa ccggaaguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  6389
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt1)

<400>  6389
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagcuucu ccaccagcgc cuucggcccc guggccuucu      120

cccuggggcu ccugcugguc cucccggcgg ccuuccccgc ccccgugccc ccgggcgagg      180

acagcaagga cguggccgcg ccccaccgcc agccccugac cuccagcgag cggaucgaca      240

agcagauccg cuacauccug gacgggaucu ccgcccuccg gaaggagacg ugcaacaaga      300

gcaacaugug cgaguccagc aaggaggccc uggccgagaa caaccugaac cuccccaaga      360

uggccgagaa ggacggcugc uuccaguccg gguucaacga ggagaccugc cuggucaaga      420

ucaucaccgg ccugcucgag uucgaggugu accuggagua ccugcagaac cgcuucgaga      480

gcuccgagga gcaggcgcgg gccgugcaga ugagcaccaa gguccucauc caguuccugc      540

agaagaaggc caagaaccug gacgccauca cgaccccgga ccccaccacc aacgccuccc      600

uccugacgaa gcugcaggcg cagaaccagu ggcuccagga caugaccacc caccugaucc      660

ugcgcagcuu caaggaguuc cuccagucca gccugcgggc ccugcgccag augugaggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  6390
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt1)

<400>  6390
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcucu ggcugcgcgg cuuccugcuc gccagcugcu      120

ggaucaucgu gcgguccagc ccgacccccg gguccgaggg ccacagcgcc gcgcccgacu      180

gccccuccug cgcccuggcc gcccugccga aggacguccc caacagccag cccgagaugg      240

uggaggccgu gaagaagcac auccucaaca ugcugcaccu gaagaagcgc cccgacguca      300

cccagccggu gcccaaggcg gcccuccuga acgccauccg gaagcugcac guggggaagg      360

ucggcgagaa cggguacgug gagaucgagg acgacaucgg ccgccgggcc gagaugaacg      420

agcucaugga gcagacgucc gagaucauca ccuucgcgga gagcggcacc gcccgcaaga      480

cccugcacuu cgagaucucc aaggagggga gcgaccuguc cguggucgag cgggccgagg      540

uguggcuguu ccucaaggug cccaaggcca accgcacgcg gaccaagguc accauccgcc      600

uguuccagca gcagaagcac ccccagggca gccucgacac cggggaggag gccgaggagg      660

ugggccugaa gggggagcgg uccgagcugc uccugagcga gaaggugguc gacgcgcgca      720

aguccacgug gcacguguuc ccggugagcu ccagcaucca gcggcugcuc gaccagggca      780

aguccagccu ggacguccgc aucgccugcg agcagugcca ggagagcggc gccucccugg      840

ugcuccuggg gaagaagaag aagaaggagg aggagggcga ggggaagaag aagggcggcg      900

gggagggcgg ggccggcgcc gacgaggaga aggagcagag ccaccggccc uuccugaugc      960

uccaggcgcg ccaguccgag gaccaccccc accggcgccg gcgccggggg cuggagugcg     1020

acggcaaggu gaacaucugc ugcaagaagc aguucuucgu cagcuucaag gacaucggcu     1080

ggaacgacug gaucaucgcc cccuccgggu accacgccaa cuacugcgag ggcgagugcc     1140

cgagccacau cgccgggacc uccggcagcu cccugagcuu ccacuccacc gugaucaacc     1200

acuaccgcau gcgcgggcac agccccuucg ccaaccucaa guccugcugc gugcccacca     1260

agcugcggcc caugagcaug cuguacuacg acgacggcca gaacaucauc aagaaggaca     1320

uccagaacau gaucgucgag gagugcggcu gcuccugagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  6391
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt1)

<400>  6391
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccugc ccgggcgcgc ccucggcgcc gcgugccugc      120

ugcuccuggc cgccgggugg cugggcccgg aggccugggg gagccccacc ccgcccccga      180

cccccgccgc gcccccgccc ccgcccccgc ccggcucccc cggcgggagc caggacacgu      240

gcaccuccug cggcggguuc cggcgccccg aggagcucgg ccggguggac ggggacuucc      300

uggaggccgu caagcgccac auccugagcc ggcuccagau gcgcggccgg cccaacauca      360

cccacgccgu gcccaaggcc gcgaugguga ccgcccugcg caagcugcac gccggcaagg      420

uccgggagga cgggcgcgug gagauccccc accucgacgg ccacgccucc cccggggccg      480

acggccagga gcgggugagc gagaucaucu ccuucgcgga gacggacggc cuggccagcu      540

cccgcguccg gcuguacuuc uucaucagca acgaggggaa ccagaaccuc uucguggugc      600

aggccucccu guggcuguac cucaagcugc ugcccuacgu ccucgagaag ggcagccgcc      660

ggaaggugcg cgugaagguc uacuuccagg agcaggggca cggcgaccgg uggaacaugg      720

uggagaagcg cguggaccug aagcgguccg gguggcacac cuucccccug accgaggcca      780

uccaggcccu cuucgagcgc ggcgagcggc gccugaaccu ggacguccag ugcgacagcu      840

gccaggagcu cgcgguggug cccgucuucg uggaccccgg cgaggagucc caccgccccu      900

ucguggucgu gcaggcccgg cugggggaca gccgccaccg gauccgcaag cggggccugg      960

agugcgacgg gcgcaccaac cucugcugcc ggcagcaguu cuucaucgac uuccgccuga     1020

ucggcuggaa cgacuggauc aucgccccga cgggguacua cggcaacuac ugcgagggcu     1080

ccugccccgc cuaccuggcc ggggugcccg gcagcgcguc cagcuuccac accgccgucg     1140

ugaaccagua ccggaugcgc gggcucaacc ccggcaccgu caacagcugc ugcaucccga     1200

ccaagcuguc cacgaugagc augcuguacu ucgacgacga guacaacauc gugaagcggg     1260

acgugcccaa caugaucguc gaggagugcg ggugcgccug aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  6392
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt1)

<400>  6392
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugcgcg ugcuccugcu gaccgcccuc acccugugcc      120

acggcuucaa ccuggacacg gagaacgcga ugaccuucca ggagaacgcc cggggguucg      180

gccagagcgu cgugcagcuc cagggguccc gcguggucgu gggcgccccc caggagaucg      240

uggccgccaa ccagcggggg agccuguacc agugcgacua cuccaccggc agcugcgagc      300

cgauccgccu gcaggucccc guggaggcgg ugaacauguc ccucggccug agccuggccg      360

ccaccacguc ccccccccag cuccuggccu gcgggccgac cguccaccag accugcagcg      420

agaacaccua cgugaagggc cugugcuucc ucuucggguc caaccugcgg cagcagcccc      480

agaaguuccc cgaggcgcug cgcggcugcc cccaggagga cagcgacauc gccuuccuca      540

ucgacggguc cggcagcauc aucccgcacg acuuccggcg caugaaggag uucgugucca      600

cggucaugga gcagcugaag aaguccaaga cccuguucuc ccucaugcag uacagcgagg      660

aguuccggau ccacuucacc uucaaggagu uccagaacaa ccccaacccc cgcucccugg      720

ugaagcccau cacccagcug cucggccgga cgcacaccgc caccgggauc cgcaaggugg      780

uccgggagcu guucaacauc accaacggcg cccgcaagaa cgccuucaag auccuggugg      840

ugaucacgga cggggagaag uucggcgacc cgcucggcua cgaggacguc auccccgagg      900

cggaccggga gggggugauc cgcuacguga ucggcgucgg ggacgccuuc cggagcgaga      960

agucccgcca ggagcugaac accaucgcca gcaagccccc ccgggaccac guguuccagg     1020

ugaacaacuu cgaggcccug aagaccaucc agaaccagcu ccgcgagaag aucuucgcca     1080

ucgagggcac ccagacgggg agcuccagcu ccuucgagca cgagaugagc caggagggcu     1140

ucuccgcggc caucaccagc aacggcccgc ugcuguccac cgucgggagc uacgacuggg     1200

ccggcggggu guuccucuac accuccaagg agaaguccac guucaucaac augacccggg     1260

ucgacuccga caugaacgac gccuaccugg gcuacgccgc ggccaucauc cugcgcaacc     1320

gcgugcagag ccucgugcug ggggcccccc gguaccagca caucggccug gucgccaugu     1380

uccgccagaa caccggcaug ugggagucca acgccaacgu gaaggggacc cagaucggcg     1440

cguacuucgg ggccagccuc ugcuccgugg acgucgacag caacggcucc acggaccugg     1500

ugcugaucgg ggccccccac uacuacgagc agacccgggg cggccaggug agcgucugcc     1560

cccucccgcg cgggcgggcc cgcuggcagu gcgacgcggu gcuguacggc gagcaggggc     1620

agcccugggg ccgguucggc gccgcccuga ccgugcucgg ggacgucaac ggcgacaagc     1680

ugaccgacgu ggccaucggg gcccccggcg aggaggacaa ccgcggggcg guguaccugu     1740

uccacggcac guccggcagc gggaucagcc ccucccacag ccagcggauc gccggcucca     1800

agcucagccc gcgccugcag uacuucgggc agucccugag cggcgggcag gaccugacca     1860

uggacggccu cgucgaccug accgugggcg cccaggggca cgugcugcuc cugcgguccc     1920

agcccguccu gcgcgugaag gccaucaugg aguucaaccc ccgggaggug gcccgcaacg     1980

ucuucgagug caacgaccag guggugaagg gcaaggaggc gggggagguc cgggugugcc     2040

uccacgugca gaaguccacc cgcgaccggc ugcgcgaggg ccagauccag uccgucguga     2100

cguacgaccu ggcccucgac agcgggcggc cccacucccg cgccguguuc aacgagacca     2160

agaacagcac ccgccggcag acccaggucc ugggccugac ccagacgugc gagacccuca     2220

agcugcagcu gccgaacugc aucgaggacc ccgugucccc caucgugcuc cgccugaacu     2280

ucagccuggu cggcaccccg cucuccgccu ucgggaaccu gcggcccgug cuggccgagg     2340

acgcgcagcg ccucuucacc gcccuguucc ccuucgagaa gaacugcggc aacgacaaca     2400

ucugccagga cgaccugagc aucacguucu ccuucaugag ccucgacugc cugguggucg     2460

ggggcccccg ggaguucaac gugaccguga ccguccgcaa cgacggggag gacagcuacc     2520

ggacccaggu gacguucuuc uucccgcugg accucuccua ccgcaaggug agcacccugc     2580

agaaccagcg gucccagcgc agcuggcggc uggccugcga guccgccagc uccaccgagg     2640

ucagcggcgc gcucaagucc accagcugcu ccaucaacca ccccaucuuc cccgagaaca     2700

gcgaggugac guucaacauc accuucgacg uggacuccaa ggccagccug ggcaacaagc     2760

ugcuccugaa ggccaacguc accuccgaga acaacaugcc ccgcaccaac aagacggagu     2820

uccagcugga gcucccggug aaguacgccg uguacauggu cgugaccagc cacggggugu     2880

ccaccaagua ccugaacuuc accgccagcg agaacacguc ccgggucaug cagcaccagu     2940

accaggugag caaccugggc cagcgcagcc uccccaucuc ccuggucuuc cuggugcccg     3000

ugcggcucaa ccagaccguc aucugggacc gcccccaggu gaccuucagc gagaaccugu     3060

ccagcacaug ccacacgaag gagcggcugc cgucccacag cgacuuccuc gcggagcugc     3120

gcaaggcccc cguggucaac ugcuccaucg ccgugugcca gcggauccag ugcgacaucc     3180

ccuucuucgg gauccaggag gaguucaacg ccacccugaa gggcaaccuc agcuucgacu     3240

gguacaucaa gaccucccac aaccaccucc ugaucgugag caccgccgag auccucuuca     3300

acgacuccgu cuucacgcug cugcccggcc agggggcguu cgugcgcagc cagaccgaga     3360

ccaaggugga gccguucgag guccccaacc cccucccccu gaucgugggc uccagcgugg     3420

ggggccugcu ccugcuggcc cucaucaccg ccgcccugua caagcugggg uucuucaagc     3480

ggcaguacaa ggacaugaug uccgagggcg gcccgcccgg ggccgagccc cagugaggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  6393
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt1)

<400>  6393
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucagccuga agacccuccc cuuccugcug cuccugcacg      120

ugcagaucuc caaggccuuc ccggucagcu ccaaggagaa gaacaccaag acggugcagg      180

acuaccugga gaaguucuac cagcucccca gcaaccagua ccaguccacc cgcaagaacg      240

gcaccaacgu gaucgucgag aagcugaagg agaugcagcg guucuucggg cugaacguga      300

ccggcaagcc caacgaggag acgcucgaca ugaugaagaa gccccgcugc ggggugccgg      360

acagcggcgg guucaugcug acccccggca accccaagug ggagcggacc aaccugaccu      420

accgcauccg gaacuacacg ccccagcucu ccgaggccga ggucgagcgc gcgaucaagg      480

acgccuucga gcuguggagc guggccuccc cgcugaucuu cacccggauc agccagggcg      540

aggccgacau caacaucgcc uucuaccagc gcgaccacgg ggacaacucc cccuucgacg      600

gccccaacgg gauccucgcg cacgccuucc agcccggcca ggggaucggc ggcgacgccc      660

acuucgacgc cgaggagacc uggaccaaca cgagcgcgaa cuacaaccug uuccuggugg      720

ccgcccacga guucgggcac ucccucggcc uggcccacag cuccgacccg ggggcccuga      780

uguaccccaa cuacgcguuc cgggagacca gcaacuacuc ccucccccag gacgacaucg      840

acggcaucca ggccaucuac ggccugagcu ccaaccccau ccagccgacc gggcccagca      900

cccccaagcc cugcgacccg agccugacgu ucgacgccau caccacccuc cgcggcgaga      960

uccuguucuu caaggaccgg uacuucuggc gccggcaccc ccagcugcag cgcgucgaga     1020

ugaacuucau cucccucuuc uggcccagcc ugcccaccgg gauccaggcc gccuacgagg     1080

acuucgaccg ggaccugauc uuccucuuca agggcaacca guacugggcg cuguccgggu     1140

acgacauccu gcagggcuac ccgaaggaca ucagcaacua cggcuucccc uccagcgugc     1200

aggccaucga cgccgccgug uucuaccgcu ccaagacgua cuucuucguc aacgaccagu     1260

ucuggcggua cgacaaccag cgccaguuca uggagcccgg guaccccaag agcaucuccg     1320

gcgccuuccc ggggaucgag agcaaggugg acgcgguguu ccagcaggag cacuucuucc     1380

acgucuucuc cggcccccgg uacuacgccu ucgaccucau cgcccagcgc gugacccggg     1440

uggcccgcgg gaacaagugg cugaacugcc gcuacggcug aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  6394
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt1)

<400>  6394
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguggc agccccucgu gcugguccug cucgugcugg      120

gcugcugcuu cgccgccccg cgccagcggc aguccacccu gguccucuuc cccggggacc      180

ugcgcaccaa ccugacggac cggcagcucg cggaggagua ccuguaccgc uacggcuaca      240

cccggguggc cgagaugcgc ggggagagca agucccuggg ccccgcccuc cugcugcucc      300

agaagcagcu gagccugccc gagaccgggg agcucgacuc cgccacccug aaggccaugc      360

ggacgccgcg cugcggcgug cccgaccugg gccgguucca gaccuucgag ggggaccuca      420

aguggcacca ccacaacauc accuacugga uccagaacua cagcgaggac cugccccgcg      480

cggugaucga cgacgccuuc gcccgggccu ucgcgcugug guccgccguc acgccccuca      540

ccuucacccg cguguacagc cgggacgccg acaucgugau ccaguucggc gucgccgagc      600

acggggacgg cuacccguuc gacgggaagg acggccugcu ggcccacgcg uucccgcccg      660

gccccgggau ccagggcgac gcccacuucg acgacgacga gcucuggucc cuggggaagg      720

gcgugguggu ccccacccgc uucggcaacg ccgacggggc cgccugccac uuccccuuca      780

ucuucgaggg ccggagcuac uccgcgugca ccacggacgg gcgcagcgac ggccugcccu      840

ggugcuccac caccgccaac uacgacaccg acgaccgguu cggguucugc cccagcgagc      900

gccucuacac gcaggacggc aacgccgacg gcaagccgug ccaguucccc uucaucuucc      960

aggggcaguc cuacagcgcc ugcaccaccg acggccgguc cgacggguac cgcuggugcg     1020

ccaccacggc gaacuacgac cgggacaagc uguucggcuu cugccccacc cgcgccgaca     1080

gcaccgugau gggcggcaac uccgccggcg agcugugcgu guuccccuuc accuuccucg     1140

ggaaggagua cagcacgugc accagcgagg gccgcgggga cggccggcug uggugcgcca     1200

ccaccuccaa cuucgacagc gacaagaagu ggggguucug cccggaccag ggcuacuccc     1260

uguuccucgu cgccgcgcac gaguucggcc acgcccuggg gcuggaccac agcuccgugc     1320

ccgaggcccu cauguacccc auguaccgcu ucacggaggg gcccccgcug cacaaggacg     1380

acgugaacgg gauccggcac cuguacggcc cccgccccga gcccgagccg cggccgccca     1440

ccaccaccac gccccagccc accgccccgc ccaccgucug ccccaccggc ccgcccacgg     1500

ugcaccccag cgagcgcccc accgcggggc ccaccggccc gcccuccgcc gggcccaccg     1560

gcccgcccac cgccgggccc agcacggcca ccaccgugcc ccucuccccc gucgacgacg     1620

ccugcaacgu gaacaucuuc gacgcgaucg ccgagaucgg caaccagcug uaccuguuca     1680

aggacggcaa guacuggcgg uucagcgagg ggcgcggcuc ccggccccag gggcccuucc     1740

ucaucgccga caaguggccg gcccugcccc gcaagcugga cagcguguuc gaggagcggc     1800

ucuccaagaa gcuguucuuc uucagcggcc gccaggucug gguguacacc ggggccuccg     1860

uccugggccc ccggcgccug gacaagcucg gccugggggc ggacguggcc caggugacgg     1920

gcgcccugcg gagcgggcgc ggcaagaugc uccuguucuc cgggcggcgc cuguggcggu     1980

ucgacgucaa ggcccagaug guggaccccc gcagcgccuc cgagguggac cgcauguucc     2040

cgggcguccc ccucgacacc cacgacgugu uccaguaccg ggagaaggcg uacuucugcc     2100

aggaccgcuu cuacuggcgg gugagcagcc gcuccgagcu gaaccagguc gaccaggugg     2160

gcuacgugac cuacgacauc cugcagugcc ccgaggacug aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  6395
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt1)

<400>  6395
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg ugcuggccgc cuuccucuuc cugagcugga      120

cccacugccg cgcgcugccg cuccccuccg ggggcgacga ggacgaccug agcgaggagg      180

accugcaguu cgccgagcgg uaccuccgcu ccuacuacca ccccaccaac cuggccggga      240

uccugaagga gaacgccgcc agcuccauga cggagcggcu ccgcgagaug cagagcuucu      300

ucggccugga ggucaccggg aagcuggacg acaacacccu cgacgugaug aagaagcccc      360

ggugcggcgu gccggacguc ggcgaguaca acguguuccc ccgcacccug aaguggucca      420

agaugaaccu gacguaccgg aucgugaacu acacccccga caugacccac agcgaggucg      480

agaaggcguu caagaaggcc uucaaggugu gguccgacgu gacgccccuc aacuucaccc      540

gccugcacga cgggaucgcc gacaucauga ucagcuucgg caucaaggag cacggggacu      600

ucuacccguu cgacggcccc uccgggcugc ucgcccacgc guucccgccc ggccccaacu      660

acggcgggga cgcccacuuc gacgacgacg agaccuggac cagcuccagc aagggcuaca      720

accuguuccu ggucgccgcc cacgaguucg ggcacucccu cggccuggac cacagcaagg      780

accccggcgc ccugauguuc cccaucuaca ccuacacggg gaagucccac uucaugcucc      840

ccgacgacga cgugcagggc auccagagcc uguacgggcc gggcgacgag gaccccaacc      900

ccaagcaccc caagaccccg gacaagugcg accccucccu gagccucgac gcgaucacca      960

gccugcgcgg ggagaccaug aucuucaagg accgguucuu cuggcggcug cacccccagc     1020

aggucgacgc cgagcuguuc cugacgaagu ccuucuggcc cgagcugccg aaccgcaucg     1080

acgccgccua cgagcacccc agccacgacc ucaucuucau cuuccggggc cgcaaguucu     1140

gggcccugaa cggcuacgac auccuggagg gguaccccaa gaagaucucc gagcucggcc     1200

ugcccaagga ggugaagaag aucagcgcgg ccgugcacuu cgaggacacc gggaagaccc     1260

uccucuucuc cggcaaccag guguggcggu acgacgacac caaccacauc auggacaagg     1320

acuacccgcg ccugaucgag gaggacuucc ccgggaucgg cgacaagguc gacgccgugu     1380

acgagaagaa cggcuacauc uacuucuuca acgggcccau ccaguucgag uacagcaucu     1440

gguccaaccg gaucgugcgc gucaugccgg ccaacagcau ccuguggugc ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6396
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt1)

<400>  6396
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acaccacgga ggacuacgac accaccaccg      120

aguucgacua cggcgacgcc acgccgugcc agaaggugaa cgagcgcgcc uucggggcgc      180

agcugcuccc gccccuguac agccuggucu ucgugaucgg ccucgugggg aacauccugg      240

ucgugcuggu gcucguccag uacaagcggc ugaagaacau gaccuccauc uaccugcuca      300

accuggccau cagcgaccuc cucuuccugu ucacccugcc cuucuggauc gacuacaagc      360

ucaaggacga cuggguguuc ggcgacgcca ugugcaagau ccuguccggg uucuacuaca      420

ccggccugua cagcgagauc uucuucauca uccuccugac gaucgaccgc uaccuggcca      480

ucgugcacgc cgucuucgcg cuccgggccc gcaccgugac cuucggcgug aucaccucca      540

ucaucaucug ggcccuggcc auccuggcga gcaugcccgg gcucuacuuc uccaagacgc      600

agugggaguu cacccaccac acgugcagcc ugcacuuccc ccacgagucc cugcgggagu      660

ggaagcuguu ccaggcccug aagcugaacc ucuucggccu gguccugccc cuccugguga      720

ugaucaucug cuacaccggg aucaucaaga uccugcuccg ccggcccaac gagaagaagu      780

ccaaggccgu gcgccugauc uucgucauca ugaucaucuu cuuccuguuc uggaccccgu      840

acaaccucac cauccugauc agcguguucc aggacuuccu guucacccac gagugcgagc      900

agagccggca ccucgaccug gccgugcagg ucaccgaggu gaucgccuac acgcacugcu      960

gcgugaaccc cgucaucuac gcguucgugg gcgagcgcuu ccggaaguac cugcgccagc     1020

uguuccaccg gcgcguggcc guccaccucg ugaaguggcu gcccuuccuc uccgucgacc     1080

ggcuggagcg cgugagcucc accagccccu ccaccgggga gcacgagcug agcgccggcu     1140

ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  6397
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt1)

<400>  6397
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcacccugg ccugccuccu gcugcucggc ugcggguacc      120

uggcccacgu gcuggcggag gaggccgaga ucccccggga ggugaucgag cgccucgccc      180

ggagccagau ccacuccauc cgcgaccugc agcggcugcu cgagaucgac agcgugggcu      240

ccgaggacag ccuggacacc ucccugcgcg cccacggggu gcacgccacg aagcacgucc      300

cggagaagcg gccccucccc auccgccgga agcgcagcau cgaggaggcg gugcccgccg      360

ugugcaagac ccggaccguc aucuacgaga ucccgcgcuc ccagguggac cccaccagcg      420

ccaacuuccu gaucuggccg cccugcgugg aggucaagcg gugcacgggc ugcugcaaca      480

ccuccagcgu gaagugccag cccucccgcg ugcaccaccg gagcgucaag guggccaagg      540

uggaguacgu ccgcaagaag cccaagcuga aggaggucca ggugcggcuc gaggagcacc      600

uggagugcgc gugcgccacc accucccuga accccgacua ccgcgaggag gacacggggc      660

ggccccgcga gagcggcaag aagcggaagc gcaagcgccu caagccgacc ugaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  6398
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt1)

<400>  6398
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaccgcugcu gggcccuguu ccucagccug ugcugcuacc      120

ugcggcucgu guccgccgag ggcgacccca ucccggagga gcuguacgag augcugagcg      180

accacuccau ccgcagcuuc gacgaccucc agcggcugcu gcacggggac cccggcgagg      240

aggacggggc ggagcucgac cugaacauga cccgcuccca cagcggcggg gagcuggagu      300

cccucgcccg gggccgccgg agccugggcu cccugaccau cgccgagccc gccaugaucg      360

ccgagugcaa gacgcgcacc gaggucuucg agaucagccg gcgccucauc gaccggacca      420

acgcgaacuu ccuggugugg cccccgugcg uggaggucca gcgcugcucc gggugcugca      480

acaaccggaa cgugcagugc cgccccaccc aggugcagcu gcggcccguc caggugcgca      540

agaucgagau cgugcggaag aagcccaucu ucaagaaggc cacggucacc cucgaggacc      600

accuggccug caagugcgag accguggccg cggcccgccc ggugacccgg agccccggcg      660

ggucccagga gcagcgcgcc aagacgcccc agacccgggu caccauccgc accgugcgcg      720

ugcggcggcc cccgaagggc aagcaccgca aguucaagca cacgcacgac aagaccgccc      780

ugaaggagac ccucggggcc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  6399
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt1)

<400>  6399
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguucg gccuccugcu gcucaccucc gcccuggccg      120

ggcagcgcca gggcacccag gcggagagca accuguccag caaguuccag uucuccagca      180

acaaggagca gaacggggug caggaccccc agcacgagcg gaucaucacg gucuccacca      240

acggcagcau ccacuccccg cgcuuccccc acaccuaccc ccggaacacc gugcucgugu      300

ggcgccuggu cgccguggag gagaacgugu ggauccagcu gacguucgac gagcgguucg      360

ggcucgagga ccccgaggac gacaucugca aguacgacuu cgucgaggug gaggagccga      420

gcgacggcac cauccugggc cgcuggugcg gguccggcac cgugcccggg aagcagauca      480

gcaagggcaa ccagauccgg auccgcuucg ucuccgacga guacuucccc agcgagcccg      540

gguucugcau ccacuacaac aucgugaugc cgcaguucac cgaggccgug ucccccagcg      600

uccugccgcc cuccgcccuc ccccuggacc ugcucaacaa cgccaucacg gcguucagca      660

cccuggagga ccugauccgg uaccucgagc ccgagcgcug gcagcuggac cuggaggacc      720

ucuaccggcc caccuggcag cugcugggca aggccuucgu guucggccgc aagucccggg      780

uggucgaccu caaccugcug accgaggagg ugcgccucua cagcugcacg ccccggaacu      840

ucagcguguc cauccgcgag gagcugaagc ggaccgacac caucuucugg ccggggugcc      900

ugcucgucaa gcgcugcggc gggaacugcg ccugcugccu gcacaacugc aacgagugcc      960

agugcgugcc cagcaaggug accaagaagu accacgaggu ccugcagcuc cggcccaaga     1020

cgggcgugcg cggccugcac aagucccuga ccgacguggc ccucgagcac cacgaggagu     1080

gcgacugcgu cugccggggg agcaccggcg ggugaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  6400
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt1)

<400>  6400
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgccuga ucuucgugua cacccucauc ugcgccaacu      120

ucugcagcug ccgggacacc uccgccacgc cccagagcgc guccaucaag gcccugcgca      180

acgccaaccu gcggcgcgac gaccucuacc ggcgcgacga gaccauccag gucaagggca      240

acggguacgu gcagagcccc cgguucccca acuccuaccc ccgcaaccug cugcucaccu      300

ggcggcugca cagccaggag aacacccgca uccagcuggu guucgacaac caguucggcc      360

ucgaggaggc cgagaacgac aucugccggu acgacuucgu cgagguggag gacaucuccg      420

agaccagcac caucauccgc gggcgguggu gcggccacaa ggaggugccc ccgcgcauca      480

agucccggac caaccagauc aagaucaccu ucaagagcga cgacuacuuc gucgccaagc      540

ccggguucaa gaucuacuac ucccugcugg aggacuucca gcccgcggcc gccagcgaga      600

cgaacuggga guccgugacc agcuccauca gcggcguguc cuacaacagc cccuccguca      660

ccgacccgac ccucaucgcc gacgcgcugg acaagaagau cgccgaguuc gacacggugg      720

aggaccugcu caaguacuuc aaccccgaga gcuggcagga ggaccuggag aacauguacc      780

uggacacccc gcgcuaccgg ggccgcagcu accacgaccg gaaguccaag guggaccucg      840

accgccugaa cgacgacgcc aagcgguaca gcugcacgcc ccgcaacuac uccgucaaca      900

uccgcgagga gcugaagcuc gccaacgugg uguucuuccc ccggugccug cugguccagc      960

gcugcggggg caacugcggg ugcggcaccg ugaacuggcg gagcugcacg ugcaacuccg     1020

ggaagaccgu gaagaaguac cacgaggucc uccaguucga gcccggccac aucaagcgcc     1080

ggggccgcgc caagaccaug gcgcuggugg acauccagcu ggaccaccac gagcggugcg     1140

acugcaucug cagcucccgc ccgccccggu gaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  6401
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt1)

<400>  6401
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugacccaca gcaaguuccc cgccgccggc augucccgcc      120

cgcuggacac cagccuccgg cugaagacgu ucuccagcaa guccgaguac cagcuggucg      180

ugaacgcggu gcgcaagcuc caggagagcg gguucuacug guccgccguc accggcgggg      240

aggccaaccu gcugcucagc gccgagcccg ccggcaccuu ccugauccgg gacuccagcg      300

accagcgcca cuucuucacc cuguccguga agacgcagag cgggaccaag aaccuccgga      360

uccagugcga gggcggcucc uucagccugc aguccgaccc ccgcagcacc cagcccgugc      420

cgcgguucga cugcguccug aagcucgugc accacuacau gcccccgccc ggggcgcccu      480

ccuuccccag cccgcccacc gagcccucca gcgaggugcc cgagcagccc agcgcccagc      540

cccugccggg cuccccgccc cgccgggccu acuacaucua cagcgggggc gagaagaucc      600

cccugguccu cucccgcccc cugagcucca acguggccac gcugcagcac cucugccgga      660

agaccgugaa cgggcaccug gacagcuacg agaaggucac ccagcugccc ggccccaucc      720

gcgaguuccu cgaccaguac gacgcgcccc ugugaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  6402
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt1)

<400>  6402
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugcccagcg ccggccagcu ggcccucuuc gcgcugggga      120

ucguccuggc cgccugccag gcccucgaga acuccaccag cccgcugucc gccgacccgc      180

ccguggcggc cgccgugguc agccacuuca acgacugccc cgacucccac acccaguucu      240

gcuuccacgg cacgugccgc uuccuggugc aggaggacaa gcccgccugc gugugccaca      300

gcggguacgu cggcgcgcgg ugcgagcacg ccgaccuccu ggccguggug gccgccuccc      360

agaagaagca ggcgaucacc gcccuggucg uggugagcau cgucgcccuc gccgugcuga      420

ucaucacgug cgugcugauc cacugcugcc agguccgcaa gcacugcgag uggugccggg      480

cccucaucug ccgccacgag aagcccuccg cgcugcugaa ggggcggacc gccugcugcc      540

acagcgagac cgugguguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  6403
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt1)

<400>  6403
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccccgagcg gccugcgccu ccugccccug cuccugcccc      120

ugcucuggcu gcuggugcuc acccccgggc ggccggccgc cggccugucc acgugcaaga      180

ccaucgacau ggagcugguc aagcgcaagc ggaucgaggc gauccgcggg cagauccuca      240

gcaagcugcg gcuggccucc ccgcccagcc agggcgaggu gccgcccggg ccccuccccg      300

aggccgugcu ggcccuguac aacuccaccc gcgaccgggu cgccggcgag agcgcggagc      360

ccgagcccga gcccgaggcc gacuacuacg ccaaggaggu gacccgcgug cucauggucg      420

agacccacaa cgagaucuac gacaaguuca agcaguccac gcacagcauc uacauguucu      480

ucaacaccuc cgagcugcgg gaggccgugc ccgagcccgu gcugcucagc cgcgcggagc      540

ugcggcugcu ccgccugaag cugaaggucg agcagcacgu ggagcucuac cagaaguacu      600

ccaacaacag cuggcgguac cuguccaacc gccugcucgc cccgagcgac ucccccgagu      660

ggcugagcuu cgacgugacc ggcgucgugc ggcaguggcu gucccgcggg ggcgagaucg      720

agggguuccg gcucagcgcc cacugcuccu gcgacagccg cgacaacacc cuccaggugg      780

acaucaacgg cuucacgacc gggcggcgcg gcgaccuggc caccauccac ggcaugaacc      840

ggcccuuccu gcugcugaug gccacgcccc ucgagcgcgc gcagcaccuc cagagcuccc      900

gccaccggcg cgcccuggac accaacuacu gcuucagcuc caccgagaag aacugcugcg      960

uccggcagcu guacaucgac uuccgcaagg accuggggug gaaguggauc cacgagccga     1020

agggcuacca cgccaacuuc ugccuggggc ccugccccua caucuggagc cucgacaccc     1080

aguacuccaa ggugcuggcc cuguacaacc agcacaaccc cggcgccagc gcggccccgu     1140

gcugcgugcc ccaggcccuc gagccccugc ccaucgucua cuacgugggc cggaagccga     1200

agguggagca gcuguccaac augaucgucc gcagcugcaa gugcuccuga ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  6404
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt1)

<400>  6404
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg ugcugagcgc cuuccucauc cugcaccugg      120

ucaccguggc ccucucccug agcacgugcu ccacccugga cauggaccag uucaugcgca      180

agcggaucga ggcgauccgc ggccagaucc ucagcaagcu gaagcugacc agcccgcccg      240

aggacuaccc cgagcccgag gaggugcccc cggaggucau cuccaucuac aacuccaccc      300

gggaccuccu gcaggagaag gccagccgcc gggccgccgc cugcgagcgc gagcgguccg      360

acgaggagua cuacgcgaag gagguguaca agaucgacau gccgcccuuc uuccccagcg      420

agaacgccau cccgcccacc uucuaccgcc ccuacuuccg gaucgugcgc uucgacgucu      480

ccgccaugga gaagaacgcc agcaaccugg ugaaggcgga guuccgggug uuccgccucc      540

agaaccccaa ggcccggguc cccgagcagc gcaucgagcu guaccagauc cugaagucca      600

aggaccucac gagccccacc cagcgguaca ucgacuccaa gguggugaag acccgcgccg      660

agggggagug gcugagcuuc gacgucaccg acgccgugca cgaguggcug caccacaagg      720

accggaaccu cggcuucaag aucucccugc acugccccug cugcacguuc gugcccagca      780

acaacuacau caucccgaac aaguccgagg agcuggaggc ccgcuucgcg gggaucgacg      840

gcaccagcac cuacaccagc ggggaccaga agacgaucaa guccacccgg aagaagaaca      900

gcggcaagac gccccaccuc cugcugaugc uccugcccuc cuaccgccug gagagccagc      960

agaccaaccg gcgcaagaag cgcgcccucg acgccgccua cugcuuccgg aacguccagg     1020

acaacugcug ccugcgcccc cuguacaucg acuucaagcg ggaccucggc uggaagugga     1080

uccacgagcc gaagggguac aacgccaacu ucugcgcggg cgccugcccc uaccuguggu     1140

ccagcgacac ccagcacucc cgcgugcuga gccucuacaa caccaucaac cccgaggccu     1200

ccgccagccc cugcugcgug ucccaggacc uggagccgcu gaccauccuc uacuacaucg     1260

ggaagacccc caagaucgag cagcugagca acaugaucgu caaguccugc aagugcagcu     1320

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  6405
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt1)

<400>  6405
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacc uccagcgcgc ccucguggug cuggcccugc      120

ucaacuucgc gaccgugagc cugucccuga gcacgugcac cacccucgac uucggccaca      180

ucaagaagaa gcggguggag gccauccgcg ggcagauccu guccaagcug cggcucacca      240

gcccgcccga gcccaccguc augacgcacg ugcccuacca ggugcuggcc cuguacaacu      300

ccacccgcga gcuccuggag gagaugcacg gcgagcggga ggaggggugc acccaggaga      360

acaccgagag cgaguacuac gccaaggaga uccacaaguu cgacaugauc cagggccugg      420

ccgagcacaa cgagcucgcg gucugcccca aggggaucac guccaaggug uuccgcuuca      480

acgugagcuc cgucgagaag aaccggacca accuguuccg cgccgaguuc cgggugcugc      540

gcgugccgaa ccccagcucc aagcggaacg agcagcgcau cgagcuguuc cagauccugc      600

ggcccgacga gcacaucgcc aagcagcgcu acaucggcgg caagaaccug cccacccggg      660

ggaccgccga guggcucagc uucgacguca cggacaccgu gcgcgagugg cugcugcggc      720

gcgaguccaa ccucggccug gagaucagca uccacugccc gugccacacc uuccagccca      780

acggggacau ccuggagaac auccacgagg ugauggagau caaguucaag ggcgucgaca      840

acgaggacga ccacgggcgg ggcgaccucg gccgccugaa gaagcagaag gaccaccaca      900

acccccaccu gauccucaug augaucccgc cccaccggcu ggacaacccc gggcagggcg      960

ggcagcgcaa gaagcgcgcg cuggacacca acuacugcuu ccggaaccuc gaggagaacu     1020

gcugcgugcg cccccuguac aucgacuucc ggcaggaccu gggcuggaag ugggugcacg     1080

agcccaaggg cuacuacgcc aacuucugcu ccgggccgug ccccuaccuc cgcagcgccg     1140

acacgaccca cuccaccguc cugggccugu acaacacccu caaccccgag gccagcgccu     1200

cccccugcug cgugccgcag gaccuggagc cccugacgau ccucuacuac guggggcgga     1260

cccccaaggu cgagcagcug agcaacaugg uggucaagag cugcaagugc uccugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6406
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt1)

<400>  6406
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccccgugg ccgucugggc ggcccuggcc gugggccucg      120

agcugugggc cgccgcgcac gcccugccgg cccagguggc cuucaccccc uacgcgcccg      180

agcccgggag cacgugccgc cuccgggagu acuacgacca gaccgcccag augugcugcu      240

ccaagugcag cccgggccag cacgccaagg ucuucugcac caagaccucc gacaccgugu      300

gcgacagcug cgaggacucc acguacaccc agcuguggaa cugggugccc gagugccuga      360

gcugcggguc ccgcugcagc uccgaccagg ucgagaccca ggccugcacc cgggagcaga      420

accgcaucug cacgugccgg cccggcuggu acugcgcccu cagcaagcag gaggggugcc      480

gccugugcgc gccccugcgg aagugccgcc cgggcuucgg cguggcccgg cccgggaccg      540

agaccuccga cguggucugc aagcccugcg cccccggcac cuucagcaac acgaccucca      600

gcaccgacau cugccgcccg caccagaucu gcaacguggu ggccaucccc gggaacgccu      660

ccauggacgc ggucugcacc agcacguccc ccacccggag cauggccccc ggcgccgugc      720

accucccgca gcccgugucc acccgcagcc agcacaccca gcccacgccc gagccgagca      780

ccgcccccuc caccagcuuc cugcugccca uggggcccuc cccgcccgcc gagggcagca      840

ccggcgacuu cgcgcucccc gucgggcuga ucgugggcgu gacggcccug gggcuccuga      900

ucaucggcgu cgugaacugc gugaucauga cccaggucaa gaagaagccc cugugccucc      960

agcgggaggc caaggugccg caccuccccg ccgacaaggc ccgcggcacc caggggcccg     1020

agcagcagca ccuccugauc accgcgccgu ccagcuccag cuccagccug gaguccagcg     1080

ccuccgcccu ggaccggcgc gcccccacgc ggaaccagcc ccaggcgccc ggcguggagg     1140

ccagcggggc cggcgaggcc cgcgccucca ccgggagcuc cgacagcucc ccgggcggcc     1200

acgggaccca ggucaacgug accugcaucg ucaacgugug cagcagcucc gaccacagcu     1260

cccagugcag cucccaggcg agcuccacga ugggcgacac cgacagcucc cccagcgagu     1320

cccccaagga cgagcagguc cccuucagca aggaggagug cgccuuccgg ucccagcugg     1380

agaccccgga gacccugcug gggagcacgg aggagaagcc ccucccccug ggcgugcccg     1440

acgccgggau gaagccgucc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  6407
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt1)

<400>  6407
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgugaugc gccuguuccc gugcuuccuc cagcugcugg      120

ccggccucgc ccugcccgcg gucccgcccc agcagugggc ccugagcgcc gggaacggcu      180

ccagcgaggu ggaggugguc cccuuccagg aggugugggg gcgguccuac ugccgcgccc      240

ucgagcggcu gguggacguc gugagcgagu accccuccga gguggagcac auguucagcc      300

ccuccugcgu cagccugcuc cgcugcaccg gcugcugcgg ggacgagaac cugcacugcg      360

ugcccgugga gaccgccaac gucacgaugc agcugcucaa gauccggucc ggcgaccgcc      420

cgagcuacgu ggagcugacc uucucccagc acgugcggug cgagugccgc ccccugcggg      480

agaagaugaa gcccgagcgc cggcgcccca agggccgggg gaagcgccgg cgcgagaagc      540

agcggccgac cgacugccac cucugcggcg acgcgguccc ccgccgguga ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  6408
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt1)

<400>  6408
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgaccgcc agaccgacac ggcccccagc ccguccuacc      120

accuccugcc cggccggcgc cggaccgugg acgccgcggc cagccgcggg cagggccccg      180

agcccgcccc cgggggcggg gucgagggcg ugggcgcccg cgggguggcc cugaagcugu      240

ucguccagcu ccugggcugc ucccgguucg ggggcgcggu ggugcgggcc ggggaggccg      300

agcccagcgg cgccgcgcgc uccgccagcu ccggccggga ggagccccag cccgaggagg      360

gggaggagga ggaggagaag gaggaggagc gcggcccgca guggcggcug ggggcccgca      420

agcccggcag cuggaccggc gaggccgccg ucugcgcgga cuccgccccc gccgcccggg      480

ccccgcaggc gcucgcccgc gccagcgggc ggggcgggcg cguggcccgg cgcggcgccg      540

aggaguccgg gccgccccac agccccuccc ggcgcggcag cgcgucccgg gccggccccg      600

ggcgcgccag cgagaccaug aacuuccugc uguccugggu gcacuggagc cucgcccugc      660

ugcucuaccu gcaccacgcc aagugguccc aggcggcccc gauggccgag ggcgggggcc      720

agaaccacca cgaggucgug aaguucaugg acguguacca gcgcagcuac ugccacccca      780

ucgagacgcu ggucgacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      840

ccagcugcgu gccgcucaug cggugcgggg gcugcugcaa cgacgagggc cuggagugcg      900

ugcccaccga ggaguccaac aucaccaugc agaucaugcg caucaagccc caccaggggc      960

agcacaucgg cgagaugagc uuccugcagc acaacaagug cgagugccgg cccaagaagg     1020

accgcgcccg gcaggagaag aaguccgucc gcgggaaggg caaggggcag aagcggaagc     1080

gcaagaaguc ccgguacaag agcuggagcg uguacguggg cgcgcgcugc ugccucaugc     1140

cguggucccu gcccggcccc caccccugcg ggccgugcag cgagcggcgc aagcaccugu     1200

ucguccagga cccccagacc ugcaagugcu ccugcaagaa cacggacagc cggugcaagg     1260

cccgccagcu cgagcugaac gagcggaccu gccgcugcga caagccccgg cgcugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6409
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt1)

<400>  6409
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggucc cuggcccugc      120

uccuguaccu gcaccacgcc aaguggagcc aggcggcccc cauggccgag ggcgggggcc      180

agaaccacca cgaggucgug aaguucaugg acguguacca gcgcuccuac ugccacccga      240

ucgagacccu cgucgacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      300

ccagcugcgu gccccugaug cggugcgggg gcugcugcaa cgacgagggg cuggagugcg      360

ugccgaccga ggaguccaac aucacgaugc agaucaugcg caucaagccc caccagggcc      420

agcacaucgg cgagaugagc uuccuccagc acaacaagug cgagugccgg cccaagaagg      480

accgcgcccg gcaggagaag aaguccgucc gcgggaaggg caaggggcag aagcggaagc      540

gcaagaaguc ccgguacaag agcuggagcg uguacguggg cgcccgcugc ugccugaugc      600

ccuggucccu gccggggccc caccccugcg gccccugcag cgagcggcgc aagcaccucu      660

ucguccagga cccgcagacc ugcaagugcu ccugcaagaa caccgacagc cggugcaagg      720

cgcgccagcu ggagcugaac gagcggaccu gccgcugcga caagccccgg cgcugaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  6410
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt1)

<400>  6410
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcccccugc uccgccggcu gcugcucgcc gcccugcugc      120

agcucgcgcc ggcccaggcc cccguguccc agcccgacgc ccccggccac cagcgcaagg      180

ucgugagcug gaucgacgug uacacccggg cgaccugcca gccgcgcgag gucguggugc      240

cccugacggu cgagcugaug gggaccgugg ccaagcagcu cgugcccucc ugcgucaccg      300

ugcagcggug cggcgggugc ugccccgacg acggccugga gugcgugccg accgggcagc      360

accagguccg caugcagauc cugaugaucc gguaccccag cucccagcuc ggcgagauga      420

gccuggagga gcacucccag ugcgagugcc gccccaagaa gaaggacagc gccgugaagc      480

ccgaccgggc cgccacgccg caccaccgcc cccagccccg guccgugccc ggcugggaca      540

gcgcgccggg ggcccccucc cccgccgaca ucacccaccc caccccggcc cccggcccca      600

gcgcccacgc ggcccccucc accacgagcg cccugacccc ggggcccgcc gccgcggccg      660

ccgacgccgc cgcguccagc gucgccaagg gcggggccug aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  6411
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt1)

<400>  6411
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuccugg gcuucuucag cguggccugc ucccugcugg      120

ccgcggcccu ccugcccggg ccgcgcgagg cccccgccgc cgcggccgcc uucgagagcg      180

gccuggaccu cuccgacgcc gagcccgacg cgggggaggc caccgccuac gccagcaagg      240

accuggagga gcagcugcgg uccgucagcu ccguggacga gcucaugacc gugcuguacc      300

ccgaguacug gaagauguac aagugccagc ugcgcaaggg cggguggcag cacaaccggg      360

agcaggccaa ccucaacagc cgcacggagg agaccaucaa guucgcggcc gcccacuaca      420

acaccgagau ccugaagucc aucgacaacg aguggcggaa gacccagugc augccgcgcg      480

aggucugcau cgacgugggc aaggaguucg gcguggccac gaacaccuuc uucaagccgc      540

ccugcgucag cguguaccgg ugcgggggcu gcugcaacuc cgaggggcug cagugcauga      600

acaccagcac cuccuaccuc agcaagacgc uguucgagau caccgugccc cugucccagg      660

gccccaagcc cgucaccauc agcuucgcca accacaccuc cugccgcugc augagcaagc      720

ucgacgugua ccgccaggug cacuccauca uccggcggag ccugcccgcg acgcugcccc      780

agugccaggc cgccaacaag accugcccga ccaacuacau guggaacaac cacaucugcc      840

gcugccucgc ccaggaggac uucauguuca gcuccgacgc cggggacgac agcaccgacg      900

gcuuccacga caucugcggc cccaacaagg agcuggacga ggagacgugc cagugcgucu      960

gccgggcggg gcugcgcccc gccuccugcg gcccccacaa ggagcucgac cggaacagcu     1020

gccagugcgu gugcaagaac aagcuguucc cgucccagug cggggccaac cgcgaguucg     1080

acgagaacac gugccagugc gugugcaagc ggaccugccc ccgcaaccag ccccugaacc     1140

ccggcaagug cgccugcgag ugcaccgaga gcccgcagaa gugccuccug aagggcaaga     1200

aguuccacca ccagaccugc uccugcuacc ggcgccccug caccaaccgg cagaaggccu     1260

gcgagcccgg guucagcuac uccgaggagg ucugccgcug cgugcccagc uacuggaagc     1320

gcccgcagau guccugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  6412
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt1)

<400>  6412
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uaccgcgagu ggguggucgu gaacguguuc augaugcugu      120

acguccagcu cgugcagggc agcuccaacg agcacgggcc cgugaagcgg agcucccaga      180

gcacccugga gcgcuccgag cagcagaucc gggccgccag cucccuggag gagcuccugc      240

gcaucaccca cagcgaggac uggaagcugu ggcggugccg ccuccggcug aaguccuuca      300

cgagcaugga cucccgcagc gcgucccacc ggagcacccg cuucgccgcc accuucuacg      360

acaucgagac ccugaagguc aucgacgagg aguggcagcg gacgcagugc uccccgcgcg      420

agaccugcgu ggagguggcc agcgagcucg gcaaguccac caacaccuuc uucaagccgc      480

ccugcgucaa cguguuccgg ugcgggggcu gcugcaacga ggagagccug aucugcauga      540

acacguccac cagcuacauc agcaagcagc uguucgagau cuccgugccc cucaccagcg      600

uccccgagcu ggugcccgug aaggucgcca accacaccgg gugcaagugc cugcccacgg      660

cgccccgcca cccguacucc aucauccggc gcagcaucca gauccccgag gaggaccggu      720

gcucccacag caagaagcuc ugccccaucg acaugcugug ggacuccaac aagugcaagu      780

gcgugcugca ggaggagaac ccccucgccg gcaccgagga ccacagccac cuccaggagc      840

cggcccugug cggcccccac augauguucg acgaggaccg cugcgagugc gugugcaaga      900

cccccugccc caaggaccug auccagcacc cgaagaacug cuccugcuuc gagugcaagg      960

agagccugga gaccugcugc cagaagcaca agcuguucca ccccgacacg ugcuccugcg     1020

aggaccggug ccccuuccac acccgccccu gcgccagcgg gaagaccgcg ugcgccaagc     1080

acugccgguu cccgaaggag aagcgcgccg cccagggccc ccacucccgc aagaaccccu     1140

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  6413
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt2)

<400>  6413
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg agaccggcuu cgagcacucc ggccucuggg      120

ucuccguccu cgccggccuc cuccucggcg ccugccaggc ccaccccauc cccgacuccu      180

ccccccuccu ccaguucggc ggccaggucc gccagcgcua ccucuacacc gacgacgccc      240

agcagaccga ggcccaccuc gagauccgcg aggacggcac cgucggcggc gccgccgacc      300

agucccccga gucccuccuc cagcucaagg cccucaagcc cggcgucauc cagauccucg      360

gcgucaagac cucccgcuuc cucugccagc gccccgacgg cgcccucuac ggcucccucc      420

acuucgaccc cgaggccugc uccuuccgcg agcuccuccu cgaggacggc uacaacgucu      480

accaguccga ggcccacggc cucccccucc accuccccgg caacaagucc ccccaccgcg      540

accccgcccc ccgcggcccc gcccgcuucc ucccccuccc cggccucccc cccgcccucc      600

ccgagccccc cggcauccuc gccccccagc cccccgacgu cggcuccucc gacccccucu      660

ccauggucgg ccccucccag ggccgcuccc ccuccuacgc cuccugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  6414
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt2)

<400>  6414
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuccuucc ccccccuccu ccuccuccuc uucuggggcg      120

ucgucuccca cuccuucccc gccacccucg agacccagga gcaggacguc gaccucgucc      180

agaaguaccu cgagaaguac uacaaccuca agaacgacgg ccgccagguc gagaagcgcc      240

gcaacuccgg ccccgucguc gagaagcuca agcagaugca ggaguucuuc ggccucaagg      300

ucaccggcaa gcccgacgcc gagacccuca aggucaugaa gcagccccgc ugcggcgucc      360

ccgacgucgc ccaguucguc cucaccgagg gcaacccccg cugggagcag acccaccuca      420

ccuaccgcau cgagaacuac acccccgacc ucccccgcgc cgacgucgac cacgccaucg      480

agaaggccuu ccagcucugg uccaacguca ccccccucac cuucaccaag gucuccgagg      540

gccaggccga caucaugauc uccuucgucc gcggcgacca ccgcgacaac ucccccuucg      600

acggccccgg cggcaaccuc gcccacgccu uccagcccgg ccccggcauc ggcggcgacg      660

cccacuucga cgaggacgag cgcuggacca acaacuuccg cgaguacaac cuccaccgcg      720

ucgccgccca cgagcucggc cacucccucg gccucuccca cuccaccgac aucggcgccc      780

ucauguaccc cuccuacacc uucuccggcg acguccagcu cgcccaggac gacaucgacg      840

gcauccaggc caucuacggc cgcucccaga accccgucca gcccaucggc ccccagaccc      900

ccaaggccug cgacuccaag cucaccuucg acgccaucac caccauccgc ggcgagguca      960

uguucuucaa ggaccgcuuc uacaugcgca ccaaccccuu cuaccccgag gucgagcuca     1020

acuucaucuc cgucuucugg ccccagcucc ccaacggccu cgaggccgcc uacgaguucg     1080

ccgaccgcga cgagguccgc uucuucaagg gcaacaagua cugggccguc cagggccaga     1140

acguccucca cggcuacccc aaggacaucu acuccuccuu cggcuucccc cgcaccguca     1200

agcacaucga cgccgcccuc uccgaggaga acaccggcaa gaccuacuuc uucgucgcca     1260

acaaguacug gcgcuacgac gaguacaagc gcuccaugga ccccggcuac cccaagauga     1320

ucgcccacga cuuccccggc aucggccaca aggucgacgc cgucuucaug aaggacggcu     1380

ucuucuacuu cuuccacggc acccgccagu acaaguucga ccccaagacc aagcgcaucc     1440

ucacccucca gaaggccaac uccugguuca acugccgcaa gaacugagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  6415
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt2)

<400>  6415
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuccuucc ccccccuccu ccuccuccuc uucuggggcg      120

ucgucuccca cuccuucguc cucaccgagg gcaacccccg cugggagcag acccaccuca      180

ccuaccgcau cgagaacuac acccccgacc ucccccgcgc cgacgucgac cacgccaucg      240

agaaggccuu ccagcucugg uccaacguca ccccccucac cuucaccaag gucuccgagg      300

gccaggccga caucaugauc uccuucgucc gcggcgacca ccgcgacaac ucccccuucg      360

acggccccgg cggcaaccuc gcccacgccu uccagcccgg ccccggcauc ggcggcgacg      420

cccacuucga cgaggacgag cgcuggacca acaacuuccg cgaguacaac cuccaccgcg      480

ucgccgccca cgagcucggc cacucccucg gccucuccca cuccaccgac aucggcgccc      540

ucauguaccc cuccuacacc uucuccggcg acguccagcu cgcccaggac gacaucgacg      600

gcauccaggc caucuacggc cgcucccaga accccgucca gcccaucggc ccccagaccc      660

ccaaggccug cgacuccaag cucaccuucg acgccaucac caccauccgc ggcgagguca      720

uguucuucaa ggaccgcuuc uacaugcgca ccaaccccuu cuaccccgag gucgagcuca      780

acuucaucuc cgucuucugg ccccagcucc ccaacggccu cgaggccgcc uacgaguucg      840

ccgaccgcga cgagguccgc uucuucaagg gcaacaagua cugggccguc cagggccaga      900

acguccucca cggcuacccc aaggacaucu acuccuccuu cggcuucccc cgcaccguca      960

agcacaucga cgccgcccuc uccgaggaga acaccggcaa gaccuacuuc uucgucgcca     1020

acaaguacug gcgcuacgac gaguacaagc gcuccaugga ccccggcuac cccaagauga     1080

ucgcccacga cuuccccggc aucggccaca aggucgacgc cgucuucaug aaggacggcu     1140

ucuucuacuu cuuccacggc acccgccagu acaaguucga ccccaagacc aagcgcaucc     1200

ucacccucca gaaggccaac uccugguuca acugccgcaa gaacugagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  6416
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt2)

<400>  6416
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaagaaca uccucaagau ccucauggac uccuacucca      120

aggaguccaa gauccagacc guccgccgcg ucaccuccgu cucccuccuc gccgucuacc      180

ucaccaugaa caccuccucc cucguccucg ccaagcccau cgagaacacc aacgacaccu      240

ccaucaagaa cgucgagaag cuccgcaacg cccccaacga ggagaacucc aagaaggucg      300

aggacuccaa gaacgacaag gucgagcacg ucaagaacau cgaggaggcc aaggucgagc      360

aggucgcccc cgaggucaag uccaagucca cccuccgcuc cgccuccauc gccaacacca      420

acuccgagaa guacgacuuc gaguaccuca acggccucuc cuacaccgag cucaccaacc      480

ucaucaagaa caucaagugg aaccagauca acggccucuu caacuacucc accggcuccc      540

agaaguucuu cggcgacaag aaccgcgucc aggccaucau caacgcccuc caggaguccg      600

gccgcaccua caccgccaac gacaugaagg gcaucgagac cuucaccgag guccuccgcg      660

ccggcuucua ccucggcuac uacaacgacg gccucuccua ccucaacgac cgcaacuucc      720

aggacaagug cauccccgcc augaucgcca uccagaagaa ccccaacuuc aagcucggca      780

ccgccgucca ggacgagguc aucaccuccc ucggcaagcu caucggcaac gccuccgcca      840

acgccgaggu cgucaacaac ugcguccccg uccucaagca guuccgcgag aaccucaacc      900

aguacgcccc cgacuacguc aagggcaccg ccgucaacga gcucaucaag ggcaucgagu      960

ucgacuucuc cggcgccgcc uacgagaagg acgucaagac caugcccugg uacggcaaga     1020

ucgaccccuu caucaacgag cucaaggccc ucggccucua cggcaacauc accuccgcca     1080

ccgagugggc cuccgacguc ggcaucuacu accucuccaa guucggccuc uacuccacca     1140

accgcaacga caucguccag ucccucgaga aggccgucga cauguacaag uacggcaaga     1200

ucgccuucgu cgccauggag cgcaucaccu gggacuacga cggcaucggc uccaacggca     1260

agaaggucga ccacgacaag uuccucgacg acgccgagaa gcacuaccuc cccaagaccu     1320

acaccuucga caacggcacc uucaucaucc gcgccggcga caaggucucc gaggagaaga     1380

ucaagcgccu cuacugggcc ucccgcgagg ucaaguccca guuccaccgc gucgucggca     1440

acgacaaggc ccucgagguc ggcaacgccg acgacguccu caccaugaag aucuucaacu     1500

cccccgagga guacaaguuc aacaccaaca ucaacggcgu cuccaccgac aacggcggcc     1560

ucuacaucga gccccgcggc accuucuaca ccuacgagcg caccccccag caguccaucu     1620

ucucccucga ggagcucuuc cgccacgagu acacccacua ccuccaggcc cgcuaccucg     1680

ucgacggccu cuggggccag ggccccuucu acgagaagaa ccgccucacc ugguucgacg     1740

agggcaccgc cgaguucuuc gccggcucca cccgcaccuc cggcguccuc ccccgcaagu     1800

ccauccucgg cuaccucgcc aaggacaagg ucgaccaccg cuacucccuc aagaagaccc     1860

ucaacuccgg cuacgacgac uccgacugga uguucuacaa cuacggcuuc gccgucgccc     1920

acuaccucua cgagaaggac augcccaccu ucaucaagau gaacaaggcc auccucaaca     1980

ccgacgucaa guccuacgac gagaucauca agaagcucuc cgacgacgcc aacaagaaca     2040

ccgaguacca gaaccacauc caggagcucg ccgacaagua ccagggcgcc ggcauccccc     2100

ucgucuccga cgacuaccuc aaggaccacg gcuacaagaa ggccuccgag gucuacuccg     2160

agaucuccaa ggccgccucc cucaccaaca ccuccgucac cgccgagaag ucccaguacu     2220

ucaacaccuu cacccuccgc ggcaccuaca ccggcgagac cuccaagggc gaguucaagg     2280

acugggacga gauguccaag aagcucgacg gcacccucga gucccucgcc aagaacuccu     2340

gguccggcua caagacccuc accgccuacu ucaccaacua ccgcgucacc uccgacaaca     2400

agguccagua cgacgucguc uuccacggcg uccucaccga caacgccgac aucuccaaca     2460

acaaggcccc caucgccaag gucaccggcc ccuccaccgg cgccgucggc cgcaacaucg     2520

aguucuccgg caaggacucc aaggacgagg acggcaagau cgucuccuac gacugggacu     2580

ucggcgacgg cgccaccucc cgcggcaaga acuccgucca cgccuacaag aaggccggca     2640

ccuacaacgu cacccucaag gucaccgacg acaagggcgc caccgccacc gaguccuuca     2700

ccaucgagau caagaacgag gacaccacca cccccaucac caaggagaug gagcccaacg     2760

acgacaucaa ggaggccaac ggccccaucg ucgagggcgu caccgucaag ggcgaccuca     2820

acggcuccga cgacgccgac accuucuacu ucgacgucaa ggaggacggc gacgucacca     2880

ucgagcuccc cuacuccggc uccuccaacu ucaccuggcu cgucuacaag gagggcgacg     2940

accagaacca caucgccucc ggcaucgaca agaacaacuc caaggucggc accuucaagu     3000

ccaccaaggg ccgccacuac gucuucaucu acaagcacga cuccgccucc aacaucuccu     3060

acucccucaa caucaagggc cucggcaacg agaagcucaa ggagaaggag aacaacgacu     3120

ccuccgacaa ggccaccguc auccccaacu ucaacaccac caugcagggc ucccuccucg     3180

gcgacgacuc ccgcgacuac uacuccuucg aggucaagga ggagggcgag gucaacaucg     3240

agcucgacaa gaaggacgag uucggcguca ccuggacccu ccaccccgag uccaacauca     3300

acgaccgcau caccuacggc caggucgacg gcaacaaggu cuccaacaag gucaagcucc     3360

gccccggcaa guacuaccuc cucgucuaca aguacuccgg cuccggcaac uacgagcucc     3420

gcgucaacaa gugaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  6417
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt2)

<400>  6417
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguca ccuucaucuc ccuccucuuc cucuucuccu      120

ccgccuacuc caucgccaac accaacuccg agaaguacga cuucgaguac cucaacggcc      180

ucuccuacac cgagcucacc aaccucauca agaacaucaa guggaaccag aucaacggcc      240

ucuucaacua cuccaccggc ucccagaagu ucuucggcga caagaaccgc guccaggcca      300

ucaucaacgc ccuccaggag uccggccgca ccuacaccgc caacgacaug aagggcaucg      360

agaccuucac cgagguccuc cgcgccggcu ucuaccucgg cuacuacaac gacggccucu      420

ccuaccucaa cgaccgcaac uuccaggaca agugcauccc cgccaugauc gccauccaga      480

agaaccccaa cuucaagcuc ggcaccgccg uccaggacga ggucaucacc ucccucggca      540

agcucaucgg caacgccucc gccaacgccg aggucgucaa caacugcguc cccguccuca      600

agcaguuccg cgagaaccuc aaccaguacg cccccgacua cgucaagggc accgccguca      660

acgagcucau caagggcauc gaguucgacu ucuccggcgc cgccuacgag aaggacguca      720

agaccaugcc cugguacggc aagaucgacc ccuucaucaa cgagcucaag gcccucggcc      780

ucuacggcaa caucaccucc gccaccgagu gggccuccga cgucggcauc uacuaccucu      840

ccaaguucgg ccucuacucc accaaccgca acgacaucgu ccagucccuc gagaaggccg      900

ucgacaugua caaguacggc aagaucgccu ucgucgccau ggagcgcauc accugggacu      960

acgacggcau cggcuccaac ggcaagaagg ucgaccacga caaguuccuc gacgacgccg     1020

agaagcacua ccuccccaag accuacaccu ucgacaacgg caccuucauc auccgcgccg     1080

gcgacaaggu cuccgaggag aagaucaagc gccucuacug ggccucccgc gaggucaagu     1140

cccaguucca ccgcgucguc ggcaacgaca aggcccucga ggucggcaac gccgacgacg     1200

uccucaccau gaagaucuuc aacucccccg aggaguacaa guucaacacc aacaucaacg     1260

gcgucuccac cgacaacggc ggccucuaca ucgagccccg cggcaccuuc uacaccuacg     1320

agcgcacccc ccagcagucc aucuucuccc ucgaggagcu cuuccgccac gaguacaccc     1380

acuaccucca ggcccgcuac cucgucgacg gccucugggg ccagggcccc uucuacgaga     1440

agaaccgccu caccugguuc gacgagggca ccgccgaguu cuucgccggc uccacccgca     1500

ccuccggcgu ccucccccgc aaguccaucc ucggcuaccu cgccaaggac aaggucgacc     1560

accgcuacuc ccucaagaag acccucaacu ccggcuacga cgacuccgac uggauguucu     1620

acaacuacgg cuucgccguc gcccacuacc ucuacgagaa ggacaugccc accuucauca     1680

agaugaacaa ggccauccuc aacaccgacg ucaaguccua cgacgagauc aucaagaagc     1740

ucuccgacga cgccaacaag aacaccgagu accagaacca cauccaggag cucgccgaca     1800

aguaccaggg cgccggcauc ccccucgucu ccgacgacua ccucaaggac cacggcuaca     1860

agaaggccuc cgaggucuac uccgagaucu ccaaggccgc cucccucacc aacaccuccg     1920

ucaccgccga gaagucccag uacuucaaca ccuucacccu ccgcggcacc uacaccggcg     1980

agaccuccaa gggcgaguuc aaggacuggg acgagauguc caagaagcuc gacggcaccc     2040

ucgagucccu cgccaagaac uccugguccg gcuacaagac ccucaccgcc uacuucacca     2100

acuaccgcgu caccuccgac aacaaggucc aguacgacgu cgucuuccac ggcguccuca     2160

ccgacaacgc cgacaucucc aacaacaagg cccccaucgc caaggucacc ggccccucca     2220

ccggcgccgu cggccgcaac aucgaguucu ccggcaagga cuccaaggac gaggacggca     2280

agaucgucuc cuacgacugg gacuucggcg acggcgccac cucccgcggc aagaacuccg     2340

uccacgccua caagaaggcc ggcaccuaca acgucacccu caaggucacc gacgacaagg     2400

gcgccaccgc caccgagucc uucaccaucg agaucaagaa cgaggacacc accaccccca     2460

ucaccaagga gauggagccc aacgacgaca ucaaggaggc caacggcccc aucgucgagg     2520

gcgucaccgu caagggcgac cucaacggcu ccgacgacgc cgacaccuuc uacuucgacg     2580

ucaaggagga cggcgacguc accaucgagc uccccuacuc cggcuccucc aacuucaccu     2640

ggcucgucua caaggagggc gacgaccaga accacaucgc cuccggcauc gacaagaaca     2700

acuccaaggu cggcaccuuc aaguccacca agggccgcca cuacgucuuc aucuacaagc     2760

acgacuccgc cuccaacauc uccuacuccc ucaacaucaa gggccucggc aacgagaagc     2820

ucaaggagaa ggagaacaac gacuccuccg acaaggccac cgucaucccc aacuucaaca     2880

ccaccaugca gggcucccuc cucggcgacg acucccgcga cuacuacucc uucgagguca     2940

aggaggaggg cgaggucaac aucgagcucg acaagaagga cgaguucggc gucaccugga     3000

cccuccaccc cgaguccaac aucaacgacc gcaucaccua cggccagguc gacggcaaca     3060

aggucuccaa caaggucaag cuccgccccg gcaaguacua ccuccucguc uacaaguacu     3120

ccggcuccgg caacuacgag cuccgcguca acaagugagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  6418
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt2)

<400>  6418
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguca ccuucaucuc ccuccucuuc cucuucuccu      120

ccgccuacuc caugaagaag aacauccuca agauccucau ggacuccuac uccaaggagu      180

ccaagaucca gaccguccgc cgcgucaccu ccgucucccu ccucgccguc uaccucacca      240

ugaacaccuc cucccucguc cucgccaagc ccaucgagaa caccaacgac accuccauca      300

agaacgucga gaagcuccgc aacgccccca acgaggagaa cuccaagaag gucgaggacu      360

ccaagaacga caaggucgag cacgucaaga acaucgagga ggccaagguc gagcaggucg      420

cccccgaggu caaguccaag uccacccucc gcuccgccuc ccgccgccgc cgcaagcgca      480

ucgccaacac caacuccgag aaguacgacu ucgaguaccu caacggccuc uccuacaccg      540

agcucaccaa ccucaucaag aacaucaagu ggaaccagau caacggccuc uucaacuacu      600

ccaccggcuc ccagaaguuc uucggcgaca agaaccgcgu ccaggccauc aucaacgccc      660

uccaggaguc cggccgcacc uacaccgcca acgacaugaa gggcaucgag accuucaccg      720

agguccuccg cgccggcuuc uaccucggcu acuacaacga cggccucucc uaccucaacg      780

accgcaacuu ccaggacaag ugcauccccg ccaugaucgc cauccagaag aaccccaacu      840

ucaagcucgg caccgccguc caggacgagg ucaucaccuc ccucggcaag cucaucggca      900

acgccuccgc caacgccgag gucgucaaca acugcguccc cguccucaag caguuccgcg      960

agaaccucaa ccaguacgcc cccgacuacg ucaagggcac cgccgucaac gagcucauca     1020

agggcaucga guucgacuuc uccggcgccg ccuacgagaa ggacgucaag accaugcccu     1080

gguacggcaa gaucgacccc uucaucaacg agcucaaggc ccucggccuc uacggcaaca     1140

ucaccuccgc caccgagugg gccuccgacg ucggcaucua cuaccucucc aaguucggcc     1200

ucuacuccac caaccgcaac gacaucgucc agucccucga gaaggccguc gacauguaca     1260

aguacggcaa gaucgccuuc gucgccaugg agcgcaucac cugggacuac gacggcaucg     1320

gcuccaacgg caagaagguc gaccacgaca aguuccucga cgacgccgag aagcacuacc     1380

uccccaagac cuacaccuuc gacaacggca ccuucaucau ccgcgccggc gacaaggucu     1440

ccgaggagaa gaucaagcgc cucuacuggg ccucccgcga ggucaagucc caguuccacc     1500

gcgucgucgg caacgacaag gcccucgagg ucggcaacgc cgacgacguc cucaccauga     1560

agaucuucaa cucccccgag gaguacaagu ucaacaccaa caucaacggc gucuccaccg     1620

acaacggcgg ccucuacauc gagccccgcg gcaccuucua caccuacgag cgcacccccc     1680

agcaguccau cuucucccuc gaggagcucu uccgccacga guacacccac uaccuccagg     1740

cccgcuaccu cgucgacggc cucuggggcc agggccccuu cuacgagaag aaccgccuca     1800

ccugguucga cgagggcacc gccgaguucu ucgccggcuc cacccgcacc uccggcgucc     1860

ucccccgcaa guccauccuc ggcuaccucg ccaaggacaa ggucgaccac cgcuacuccc     1920

ucaagaagac ccucaacucc ggcuacgacg acuccgacug gauguucuac aacuacggcu     1980

ucgccgucgc ccacuaccuc uacgagaagg acaugcccac cuucaucaag augaacaagg     2040

ccauccucaa caccgacguc aaguccuacg acgagaucau caagaagcuc uccgacgacg     2100

ccaacaagaa caccgaguac cagaaccaca uccaggagcu cgccgacaag uaccagggcg     2160

ccggcauccc ccucgucucc gacgacuacc ucaaggacca cggcuacaag aaggccuccg     2220

aggucuacuc cgagaucucc aaggccgccu cccucaccaa caccuccguc accgccgaga     2280

agucccagua cuucaacacc uucacccucc gcggcaccua caccggcgag accuccaagg     2340

gcgaguucaa ggacugggac gagaugucca agaagcucga cggcacccuc gagucccucg     2400

ccaagaacuc cugguccggc uacaagaccc ucaccgccua cuucaccaac uaccgcguca     2460

ccuccgacaa caagguccag uacgacgucg ucuuccacgg cguccucacc gacaacgccg     2520

acaucuccaa caacaaggcc cccaucgcca aggucaccgg ccccuccacc ggcgccgucg     2580

gccgcaacau cgaguucucc ggcaaggacu ccaaggacga ggacggcaag aucgucuccu     2640

acgacuggga cuucggcgac ggcgccaccu cccgcggcaa gaacuccguc cacgccuaca     2700

agaaggccgg caccuacaac gucacccuca aggucaccga cgacaagggc gccaccgcca     2760

ccgaguccuu caccaucgag aucaagaacg aggacaccac cacccccauc accaaggaga     2820

uggagcccaa cgacgacauc aaggaggcca acggccccau cgucgagggc gucaccguca     2880

agggcgaccu caacggcucc gacgacgccg acaccuucua cuucgacguc aaggaggacg     2940

gcgacgucac caucgagcuc cccuacuccg gcuccuccaa cuucaccugg cucgucuaca     3000

aggagggcga cgaccagaac cacaucgccu ccggcaucga caagaacaac uccaaggucg     3060

gcaccuucaa guccaccaag ggccgccacu acgucuucau cuacaagcac gacuccgccu     3120

ccaacaucuc cuacucccuc aacaucaagg gccucggcaa cgagaagcuc aaggagaagg     3180

agaacaacga cuccuccgac aaggccaccg ucauccccaa cuucaacacc accaugcagg     3240

gcucccuccu cggcgacgac ucccgcgacu acuacuccuu cgaggucaag gaggagggcg     3300

aggucaacau cgagcucgac aagaaggacg aguucggcgu caccuggacc cuccaccccg     3360

aguccaacau caacgaccgc aucaccuacg gccaggucga cggcaacaag gucuccaaca     3420

aggucaagcu ccgccccggc aaguacuacc uccucgucua caaguacucc ggcuccggca     3480

acuacgagcu ccgcgucaac aagugaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  6419
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt2)

<400>  6419
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuca agaucauccu caaccgcggc aagaccauga      120

agcgcaagug ccucuccaag cgccucaugc ucgccaucac cauggccacc aucuucaccg      180

ucaacuccac ccuccccauc uacgccgccg ucgacaagaa caacgccacc gccgccgucc      240

agaacgaguc caagcgcuac accgucuccu accucaagac ccucaacuac uacgaccucg      300

ucgaccuccu cgucaagacc gagaucgaga accuccccga ccucuuccag uacuccuccg      360

acgccaagga guucuacggc aacaagaccc gcauguccuu caucauggac gagaucggcc      420

gccgcgcccc ccaguacacc gagaucgacc acaagggcau ccccacccuc gucgaggucg      480

uccgcgccgg cuucuaccuc ggcuuccaca acaaggagcu caacgagauc aacaagcgcu      540

ccuucaagga gcgcgucauc cccuccaucc ucgccaucca gaagaacccc aacuucaagc      600

ucggcaccga gguccaggac aagaucgucu ccgccaccgg ccuccucgcc ggcaacgaga      660

ccgccccccc cgaggucguc aacaacuuca cccccauccu ccaggacugc aucaagaaca      720

ucgaccgcua cgcccucgac gaccucaagu ccaaggcccu cuucaacguc cucgccgccc      780

ccaccuacga caucaccgag uaccuccgcg ccaccaagga gaagcccgag aacacccccu      840

gguacggcaa gaucgacggc uucaucaacg agcucaagaa gcucgcccuc uacggcaaga      900

ucaacgacaa caacuccugg aucaucgaca acggcaucua ccacaucgcc ccccucggca      960

agcuccacuc caacaacaag aucggcaucg agacccucac cgaggucaug aaggucuacc     1020

ccuaccucuc caugcagcac cuccaguccg ccgaccagau caagcgccac uacgacucca     1080

aggacgccga gggcaacaag aucccccucg acaaguucaa gaaggagggc aaggagaagu     1140

acugccccaa gaccuacacc uucgacgacg gcaaggucau caucaaggcc ggcgcccgcg     1200

ucgaggagga gaaggucaag cgccucuacu gggccuccaa ggaggucaac ucccaguucu     1260

uccgcgucua cggcaucgac aagccccucg aggagggcaa ccccgacgac auccucacca     1320

uggucaucua caacuccccc gaggaguaca agcucaacuc cguccucuac ggcuacgaca     1380

ccaacaacgg cggcauguac aucgagcccg agggcaccuu cuucaccuac gagcgcgagg     1440

cccaggaguc caccuacacc cucgaggagc ucuuccgcca cgaguacacc cacuaccucc     1500

agggccgcua cgccgucccc ggccaguggg gccgcaccaa gcucuacgac aacgaccgcc     1560

ucaccuggua cgaggagggc ggcgccgagc ucuucgccgg cuccacccgc accuccggca     1620

uccucccccg caaguccauc gucuccaaca uccacaacac cacccgcaac aaccgcuaca     1680

agcucuccga caccguccac uccaaguacg gcgccuccuu cgaguucuac aacuacgccu     1740

gcauguucau ggacuacaug uacaacaagg acaugggcau ccucaacaag cucaacgacc     1800

ucgccaagaa caacgacguc gacggcuacg acaacuacau ccgcgaccuc uccuccaacu     1860

acgcccucaa cgacaaguac caggaccaca ugcaggagcg caucgacaac uacgagaacc     1920

ucaccguccc cuucgucgcc gacgacuacc ucguccgcca cgccuacaag aaccccaacg     1980

agaucuacuc cgagaucucc gaggucgcca agcucaagga cgccaagucc gaggucaaga     2040

agucccagua cuucuccacc uucacccucc gcggcuccua caccggcggc gccuccaagg     2100

gcaagcucga ggaccagaag gccaugaaca aguucaucga cgacucccuc aagaagcucg     2160

acaccuacuc cugguccggc uacaagaccc ucaccgccua cuucaccaac uacaaggucg     2220

acuccuccaa ccgcgucacc uacgacgucg ucuuccacgg cuaccucccc aacgagggcg     2280

acuccaagaa cucccucccc uacggcaaga ucaacggcac cuacaagggc accgagaagg     2340

agaagaucaa guucuccucc gagggcuccu ucgaccccga cggcaagauc gucuccuacg     2400

agugggacuu cggcgacggc aacaagucca acgaggagaa ccccgagcac uccuacgaca     2460

aggucggcac cuacaccguc aagcucaagg ucaccgacga caagggcgag uccuccgucu     2520

ccaccaccac cgccgagauc aaggaccucu ccgagaacaa gcuccccguc aucuacaugc     2580

acguccccaa guccggcgcc cucaaccaga aggucgucuu cuacggcaag ggcaccuacg     2640

accccgacgg cuccaucgcc ggcuaccagu gggacuucgg cgacggcucc gacuucuccu     2700

ccgagcagaa ccccucccac gucuacacca agaagggcga guacaccguc acccuccgcg     2760

ucauggacuc cuccggccag auguccgaga agaccaugaa gaucaagauc accgaccccg     2820

ucuaccccau cggcaccgag aaggagccca acaacuccaa ggagaccgcc uccggcccca     2880

ucguccccgg cauccccguc uccggcacca ucgagaacac cuccgaccag gacuacuucu     2940

acuucgacgu caucaccccc ggcgagguca agaucgacau caacaagcuc ggcuacggcg     3000

gcgccaccug ggucgucuac gacgagaaca acaacgccgu cuccuacgcc accgacgacg     3060

gccagaaccu cuccggcaag uucaaggccg acaagcccgg ccgcuacuac auccaccucu     3120

acauguucaa cggcuccuac augcccuacc gcaucaacau cgagggcucc gucggccgcu     3180

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  6420
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt2)

<400>  6420
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcgcaagu gccucuccaa gcgccucaug cucgccauca      120

ccauggccac caucuucacc gucaacucca cccuccccau cuacgccgcc gucgacaaga      180

acaacgccac cgccgccguc cagaacgagu ccaagcgcua caccgucucc uaccucaaga      240

cccucaacua cuacgaccuc gucgaccucc ucgucaagac cgagaucgag aaccuccccg      300

accucuucca guacuccucc gacgccaagg aguucuacgg caacaagacc cgcauguccu      360

ucaucaugga cgagaucggc cgccgcgccc cccaguacac cgagaucgac cacaagggca      420

uccccacccu cgucgagguc guccgcgccg gcuucuaccu cggcuuccac aacaaggagc      480

ucaacgagau caacaagcgc uccuucaagg agcgcgucau ccccuccauc cucgccaucc      540

agaagaaccc caacuucaag cucggcaccg agguccagga caagaucguc uccgccaccg      600

gccuccucgc cggcaacgag accgcccccc ccgaggucgu caacaacuuc acccccaucc      660

uccaggacug caucaagaac aucgaccgcu acgcccucga cgaccucaag uccaaggccc      720

ucuucaacgu ccucgccgcc cccaccuacg acaucaccga guaccuccgc gccaccaagg      780

agaagcccga gaacaccccc ugguacggca agaucgacgg cuucaucaac gagcucaaga      840

agcucgcccu cuacggcaag aucaacgaca acaacuccug gaucaucgac aacggcaucu      900

accacaucgc cccccucggc aagcuccacu ccaacaacaa gaucggcauc gagacccuca      960

ccgaggucau gaaggucuac cccuaccucu ccaugcagca ccuccagucc gccgaccaga     1020

ucaagcgcca cuacgacucc aaggacgccg agggcaacaa gaucccccuc gacaaguuca     1080

agaaggaggg caaggagaag uacugcccca agaccuacac cuucgacgac ggcaagguca     1140

ucaucaaggc cggcgcccgc gucgaggagg agaaggucaa gcgccucuac ugggccucca     1200

aggaggucaa cucccaguuc uuccgcgucu acggcaucga caagccccuc gaggagggca     1260

accccgacga cauccucacc auggucaucu acaacucccc cgaggaguac aagcucaacu     1320

ccguccucua cggcuacgac accaacaacg gcggcaugua caucgagccc gagggcaccu     1380

ucuucaccua cgagcgcgag gcccaggagu ccaccuacac ccucgaggag cucuuccgcc     1440

acgaguacac ccacuaccuc cagggccgcu acgccguccc cggccagugg ggccgcacca     1500

agcucuacga caacgaccgc cucaccuggu acgaggaggg cggcgccgag cucuucgccg     1560

gcuccacccg caccuccggc auccuccccc gcaaguccau cgucuccaac auccacaaca     1620

ccacccgcaa caaccgcuac aagcucuccg acaccgucca cuccaaguac ggcgccuccu     1680

ucgaguucua caacuacgcc ugcauguuca uggacuacau guacaacaag gacaugggca     1740

uccucaacaa gcucaacgac cucgccaaga acaacgacgu cgacggcuac gacaacuaca     1800

uccgcgaccu cuccuccaac uacgcccuca acgacaagua ccaggaccac augcaggagc     1860

gcaucgacaa cuacgagaac cucaccgucc ccuucgucgc cgacgacuac cucguccgcc     1920

acgccuacaa gaaccccaac gagaucuacu ccgagaucuc cgaggucgcc aagcucaagg     1980

acgccaaguc cgaggucaag aagucccagu acuucuccac cuucacccuc cgcggcuccu     2040

acaccggcgg cgccuccaag ggcaagcucg aggaccagaa ggccaugaac aaguucaucg     2100

acgacucccu caagaagcuc gacaccuacu ccugguccgg cuacaagacc cucaccgccu     2160

acuucaccaa cuacaagguc gacuccucca accgcgucac cuacgacguc gucuuccacg     2220

gcuaccuccc caacgagggc gacuccaaga acucccuccc cuacggcaag aucaacggca     2280

ccuacaaggg caccgagaag gagaagauca aguucuccuc cgagggcucc uucgaccccg     2340

acggcaagau cgucuccuac gagugggacu ucggcgacgg caacaagucc aacgaggaga     2400

accccgagca cuccuacgac aaggucggca ccuacaccgu caagcucaag gucaccgacg     2460

acaagggcga guccuccguc uccaccacca ccgccgagau caaggaccuc uccgagaaca     2520

agcuccccgu caucuacaug cacgucccca aguccggcgc ccucaaccag aaggucgucu     2580

ucuacggcaa gggcaccuac gaccccgacg gcuccaucgc cggcuaccag ugggacuucg     2640

gcgacggcuc cgacuucucc uccgagcaga accccuccca cgucuacacc aagaagggcg     2700

aguacaccgu cacccuccgc gucauggacu ccuccggcca gauguccgag aagaccauga     2760

agaucaagau caccgacccc gucuacccca ucggcaccga gaaggagccc aacaacucca     2820

aggagaccgc cuccggcccc aucguccccg gcauccccgu cuccggcacc aucgagaaca     2880

ccuccgacca ggacuacuuc uacuucgacg ucaucacccc cggcgagguc aagaucgaca     2940

ucaacaagcu cggcuacggc ggcgccaccu gggucgucua cgacgagaac aacaacgccg     3000

ucuccuacgc caccgacgac ggccagaacc ucuccggcaa guucaaggcc gacaagcccg     3060

gccgcuacua cauccaccuc uacauguuca acggcuccua caugcccuac cgcaucaaca     3120

ucgagggcuc cgucggccgc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  6421
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt2)

<400>  6421
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguca ccuucaucuc ccuccucuuc cucuucuccu      120

ccgccuacuc cguccagaac gaguccaagc gcuacaccgu cuccuaccuc aagacccuca      180

acuacuacga ccucgucgac cuccucguca agaccgagau cgagaaccuc cccgaccucu      240

uccaguacuc cuccgacgcc aaggaguucu acggcaacaa gacccgcaug uccuucauca      300

uggacgagau cggccgccgc gccccccagu acaccgagau cgaccacaag ggcaucccca      360

cccucgucga ggucguccgc gccggcuucu accucggcuu ccacaacaag gagcucaacg      420

agaucaacaa gcgcuccuuc aaggagcgcg ucauccccuc cauccucgcc auccagaaga      480

accccaacuu caagcucggc accgaggucc aggacaagau cgucuccgcc accggccucc      540

ucgccggcaa cgagaccgcc ccccccgagg ucgucaacaa cuucaccccc auccuccagg      600

acugcaucaa gaacaucgac cgcuacgccc ucgacgaccu caaguccaag gcccucuuca      660

acguccucgc cgcccccacc uacgacauca ccgaguaccu ccgcgccacc aaggagaagc      720

ccgagaacac ccccugguac ggcaagaucg acggcuucau caacgagcuc aagaagcucg      780

cccucuacgg caagaucaac gacaacaacu ccuggaucau cgacaacggc aucuaccaca      840

ucgccccccu cggcaagcuc cacuccaaca acaagaucgg caucgagacc cucaccgagg      900

ucaugaaggu cuaccccuac cucuccaugc agcaccucca guccgccgac cagaucaagc      960

gccacuacga cuccaaggac gccgagggca acaagauccc ccucgacaag uucaagaagg     1020

agggcaagga gaaguacugc cccaagaccu acaccuucga cgacggcaag gucaucauca     1080

aggccggcgc ccgcgucgag gaggagaagg ucaagcgccu cuacugggcc uccaaggagg     1140

ucaacuccca guucuuccgc gucuacggca ucgacaagcc ccucgaggag ggcaaccccg     1200

acgacauccu caccaugguc aucuacaacu cccccgagga guacaagcuc aacuccgucc     1260

ucuacggcua cgacaccaac aacggcggca uguacaucga gcccgagggc accuucuuca     1320

ccuacgagcg cgaggcccag gaguccaccu acacccucga ggagcucuuc cgccacgagu     1380

acacccacua ccuccagggc cgcuacgccg uccccggcca guggggccgc accaagcucu     1440

acgacaacga ccgccucacc ugguacgagg agggcggcgc cgagcucuuc gccggcucca     1500

cccgcaccuc cggcauccuc ccccgcaagu ccaucgucuc caacauccac aacaccaccc     1560

gcaacaaccg cuacaagcuc uccgacaccg uccacuccaa guacggcgcc uccuucgagu     1620

ucuacaacua cgccugcaug uucauggacu acauguacaa caaggacaug ggcauccuca     1680

acaagcucaa cgaccucgcc aagaacaacg acgucgacgg cuacgacaac uacauccgcg     1740

accucuccuc caacuacgcc cucaacgaca aguaccagga ccacaugcag gagcgcaucg     1800

acaacuacga gaaccucacc guccccuucg ucgccgacga cuaccucguc cgccacgccu     1860

acaagaaccc caacgagauc uacuccgaga ucuccgaggu cgccaagcuc aaggacgcca     1920

aguccgaggu caagaagucc caguacuucu ccaccuucac ccuccgcggc uccuacaccg     1980

gcggcgccuc caagggcaag cucgaggacc agaaggccau gaacaaguuc aucgacgacu     2040

cccucaagaa gcucgacacc uacuccuggu ccggcuacaa gacccucacc gccuacuuca     2100

ccaacuacaa ggucgacucc uccaaccgcg ucaccuacga cgucgucuuc cacggcuacc     2160

uccccaacga gggcgacucc aagaacuccc uccccuacgg caagaucaac ggcaccuaca     2220

agggcaccga gaaggagaag aucaaguucu ccuccgaggg cuccuucgac cccgacggca     2280

agaucgucuc cuacgagugg gacuucggcg acggcaacaa guccaacgag gagaaccccg     2340

agcacuccua cgacaagguc ggcaccuaca ccgucaagcu caaggucacc gacgacaagg     2400

gcgaguccuc cgucuccacc accaccgccg agaucaagga ccucuccgag aacaagcucc     2460

ccgucaucua caugcacguc cccaaguccg gcgcccucaa ccagaagguc gucuucuacg     2520

gcaagggcac cuacgacccc gacggcucca ucgccggcua ccagugggac uucggcgacg     2580

gcuccgacuu cuccuccgag cagaaccccu cccacgucua caccaagaag ggcgaguaca     2640

ccgucacccu ccgcgucaug gacuccuccg gccagauguc cgagaagacc augaagauca     2700

agaucaccga ccccgucuac cccaucggca ccgagaagga gcccaacaac uccaaggaga     2760

ccgccuccgg ccccaucguc cccggcaucc ccgucuccgg caccaucgag aacaccuccg     2820

accaggacua cuucuacuuc gacgucauca cccccggcga ggucaagauc gacaucaaca     2880

agcucggcua cggcggcgcc accugggucg ucuacgacga gaacaacaac gccgucuccu     2940

acgccaccga cgacggccag aaccucuccg gcaaguucaa ggccgacaag cccggccgcu     3000

acuacaucca ccucuacaug uucaacggcu ccuacaugcc cuaccgcauc aacaucgagg     3060

gcuccgucgg ccgcugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6422
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt2)

<400>  6422
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguca ccuucaucuc ccuccucuuc cucuucuccu      120

ccgccuacuc caugaagcgc aagugccucu ccaagcgccu caugcucgcc aucaccaugg      180

ccaccaucuu caccgucaac uccacccucc ccaucuacgc cgccgucgac aagaacaacg      240

ccaccgccgc ccgccgccgc cgcaagcgcg uccagaacga guccaagcgc uacaccgucu      300

ccuaccucaa gacccucaac uacuacgacc ucgucgaccu ccucgucaag accgagaucg      360

agaaccuccc cgaccucuuc caguacuccu ccgacgccaa ggaguucuac ggcaacaaga      420

cccgcauguc cuucaucaug gacgagaucg gccgccgcgc cccccaguac accgagaucg      480

accacaaggg cauccccacc cucgucgagg ucguccgcgc cggcuucuac cucggcuucc      540

acaacaagga gcucaacgag aucaacaagc gcuccuucaa ggagcgcguc auccccucca      600

uccucgccau ccagaagaac cccaacuuca agcucggcac cgagguccag gacaagaucg      660

ucuccgccac cggccuccuc gccggcaacg agaccgcccc ccccgagguc gucaacaacu      720

ucacccccau ccuccaggac ugcaucaaga acaucgaccg cuacgcccuc gacgaccuca      780

aguccaaggc ccucuucaac guccucgccg cccccaccua cgacaucacc gaguaccucc      840

gcgccaccaa ggagaagccc gagaacaccc ccugguacgg caagaucgac ggcuucauca      900

acgagcucaa gaagcucgcc cucuacggca agaucaacga caacaacucc uggaucaucg      960

acaacggcau cuaccacauc gccccccucg gcaagcucca cuccaacaac aagaucggca     1020

ucgagacccu caccgagguc augaaggucu accccuaccu cuccaugcag caccuccagu     1080

ccgccgacca gaucaagcgc cacuacgacu ccaaggacgc cgagggcaac aagauccccc     1140

ucgacaaguu caagaaggag ggcaaggaga aguacugccc caagaccuac accuucgacg     1200

acggcaaggu caucaucaag gccggcgccc gcgucgagga ggagaagguc aagcgccucu     1260

acugggccuc caaggagguc aacucccagu ucuuccgcgu cuacggcauc gacaagcccc     1320

ucgaggaggg caaccccgac gacauccuca ccauggucau cuacaacucc cccgaggagu     1380

acaagcucaa cuccguccuc uacggcuacg acaccaacaa cggcggcaug uacaucgagc     1440

ccgagggcac cuucuucacc uacgagcgcg aggcccagga guccaccuac acccucgagg     1500

agcucuuccg ccacgaguac acccacuacc uccagggccg cuacgccguc cccggccagu     1560

ggggccgcac caagcucuac gacaacgacc gccucaccug guacgaggag ggcggcgccg     1620

agcucuucgc cggcuccacc cgcaccuccg gcauccuccc ccgcaagucc aucgucucca     1680

acauccacaa caccacccgc aacaaccgcu acaagcucuc cgacaccguc cacuccaagu     1740

acggcgccuc cuucgaguuc uacaacuacg ccugcauguu cauggacuac auguacaaca     1800

aggacauggg cauccucaac aagcucaacg accucgccaa gaacaacgac gucgacggcu     1860

acgacaacua cauccgcgac cucuccucca acuacgcccu caacgacaag uaccaggacc     1920

acaugcagga gcgcaucgac aacuacgaga accucaccgu ccccuucguc gccgacgacu     1980

accucguccg ccacgccuac aagaacccca acgagaucua cuccgagauc uccgaggucg     2040

ccaagcucaa ggacgccaag uccgagguca agaaguccca guacuucucc accuucaccc     2100

uccgcggcuc cuacaccggc ggcgccucca agggcaagcu cgaggaccag aaggccauga     2160

acaaguucau cgacgacucc cucaagaagc ucgacaccua cuccuggucc ggcuacaaga     2220

cccucaccgc cuacuucacc aacuacaagg ucgacuccuc caaccgcguc accuacgacg     2280

ucgucuucca cggcuaccuc cccaacgagg gcgacuccaa gaacucccuc cccuacggca     2340

agaucaacgg caccuacaag ggcaccgaga aggagaagau caaguucucc uccgagggcu     2400

ccuucgaccc cgacggcaag aucgucuccu acgaguggga cuucggcgac ggcaacaagu     2460

ccaacgagga gaaccccgag cacuccuacg acaaggucgg caccuacacc gucaagcuca     2520

aggucaccga cgacaagggc gaguccuccg ucuccaccac caccgccgag aucaaggacc     2580

ucuccgagaa caagcucccc gucaucuaca ugcacguccc caaguccggc gcccucaacc     2640

agaaggucgu cuucuacggc aagggcaccu acgaccccga cggcuccauc gccggcuacc     2700

agugggacuu cggcgacggc uccgacuucu ccuccgagca gaaccccucc cacgucuaca     2760

ccaagaaggg cgaguacacc gucacccucc gcgucaugga cuccuccggc cagauguccg     2820

agaagaccau gaagaucaag aucaccgacc ccgucuaccc caucggcacc gagaaggagc     2880

ccaacaacuc caaggagacc gccuccggcc ccaucguccc cggcaucccc gucuccggca     2940

ccaucgagaa caccuccgac caggacuacu ucuacuucga cgucaucacc cccggcgagg     3000

ucaagaucga caucaacaag cucggcuacg gcggcgccac cugggucguc uacgacgaga     3060

acaacaacgc cgucuccuac gccaccgacg acggccagaa ccucuccggc aaguucaagg     3120

ccgacaagcc cggccgcuac uacauccacc ucuacauguu caacggcucc uacaugcccu     3180

accgcaucaa caucgagggc uccgucggcc gcugaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  6423
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt2)

<400>  6423
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucgccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagucca uccgcccccc cuaccccucc uacggcuacg      240

agcccauggg cggcuggcuc caccaccaga ucauccccgu ccucucccag cagcaccccc      300

ccacccacac ccuccagccc caccaccaca uccccgucgu ccccgcccag cagcccguca      360

ucccccagca gcccaugaug cccguccccg gccagcacuc caugaccccc auccagcacc      420

accagcccaa ccuccccccc cccgcccagc agcccuacca gccccagccc guccagcccc      480

agccccacca gcccaugcag ccccagcccc ccguccaccc caugcagccc cucccccccc      540

agcccccccu cccccccaug uuccccaugc agccccuccc ccccaugcuc cccgaccuca      600

cccucgaggc cuggcccucc accgacaaga ccaagcgcga ggaggucgac ugaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  6424
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt2)

<400>  6424
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccaguc cauccgcccc cccuaccccu      180

ccuacggcua cgagcccaug ggcggcuggu gaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  6425
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt2)

<400>  6425
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccaguc cauccgcccc ccccccaugc      180

uccccgaccu cacccucgag gccuggcccu ccaccgacaa gaccaagcgc gaggaggucg      240

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  6426
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt2)

<400>  6426
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccag accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gagguccuca ccccccucaa gugguaccag uccauccgcc      240

cccccuaccc cuccuacggc uacgagccca ugggcggcug gugaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  6427
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt2)

<400>  6427
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccag accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gagguccuca ccccccucaa gugguaccag uccauccgcc      240

ccccccccau gcuccccgac cucacccucg aggccuggcc cuccaccgac aagaccaagc      300

gcgaggaggu cgacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  6428
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt2)

<400>  6428
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccucguc ggcgccgccu      120

ucgccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagucca ugauccgccc ccccuacucc uccuacggcu      240

acgagcccau gggcggcugg cuccaccacc agaucauccc cgucgucucc cagcagcacc      300

cccucaccca cacccuccag ucccaccacc acauccccgu cguccccgcc cagcagcccc      360

gcguccgcca gcaggcccuc augcccgucc ccggccagca guccaugacc cccacccagc      420

accaccagcc caaccucccc cuccccgccc agcagcccuu ccagccccag cccguccagc      480

cccagcccca ccagcccaug cagccccagc cccccgucca gcccaugcag ccccuccucc      540

cccagccccc ccuccccccc auguuccccc uccgcccccu cccccccauc cuccccgacc      600

uccaccucga ggccuggccc gccaccgaca agaccaagca ggaggagguc gacugaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  6429
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt2)

<400>  6429
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccaguc caugauccgc ccccccuacu      180

ccuccuacgg cuacgagccc augggcggcu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6430
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt2)

<400>  6430
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccaguc caugauccgc ccccccccca      180

uccuccccga ccuccaccuc gaggccuggc ccgccaccga caagaccaag caggaggagg      240

ucgacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6431
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt2)

<400>  6431
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccag accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gagguccuca ccccccucaa gugguaccag uccaugaucc      240

gcccccccua cuccuccuac ggcuacgagc ccaugggcgg cuggugagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6432
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt2)

<400>  6432
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccag accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gagguccuca ccccccucaa gugguaccag uccaugaucc      240

gccccccccc cauccucccc gaccuccacc ucgaggccug gcccgccacc gacaagacca      300

agcaggagga ggucgacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6433
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt2)

<400>  6433
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccuacacc uccuacggcu      240

acgagcccau gggcggcugg cuccaccacc agaucauccc cgucgucucc cagcagaccc      300

cccaguccca cgcccuccag ccccaccacc acauccccau gguccccgcc cagcagcccg      360

gcauccccca gcagcccaug augccccucc ccggccagca cuccaugacc cccacccagc      420

accaccagcc caaccucccc cuccccgccc agcagcccuu ccagccccag cccguccagc      480

cccagcccca ccagccccuc cagccccagu cccccaugca ccccauccag ccccuccucc      540

cccagccccc ccuccccccc auguucucca ugcagucccu ccuccccgac cucccccucg      600

aggccuggcc cgccaccgac aagaccaagc gcgaggaggu cgacugagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6434
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt2)

<400>  6434
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccagaa caugauccgc caccccuaca      180

ccuccuacgg cuacgagccc augggcggcu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6435
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt2)

<400>  6435
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccagaa caugauccgc caccccuccc      180

uccuccccga ccucccccuc gaggccuggc ccgccaccga caagaccaag cgcgaggagg      240

ucgacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6436
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt2)

<400>  6436
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccag accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gagguccuca ccccccucaa gugguaccag aacaugaucc      240

gccaccccua caccuccuac ggcuacgagc ccaugggcgg cuggugagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6437
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt2)

<400>  6437
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccag accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gagguccuca ccccccucaa gugguaccag aacaugaucc      240

gccaccccuc ccuccucccc gaccuccccc ucgaggccug gcccgccacc gacaagacca      300

agcgcgagga ggucgacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6438
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt2)

<400>  6438
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacaucc      180

gccaccccua caccuccuac ggcuacgagc ccaugggcgg cuggcuccac caccagauca      240

uccccgucgu cucccagcag accccccagu cccacgcccu ccagccccac caccacaucc      300

ccaugguccc cgcccagcag cccggcaucc cccagcagcc caugaugccc cuccccggcc      360

agcacuccau gacccccacc cagcaccacc agcccaaccu cccccucccc gcccagcagc      420

ccuuccagcc ccagcccguc cagccccagc cccaccagcc ccuccagccc caguccccca      480

ugcaccccau ccagccccuc cucccccagc ccccccuccc ccccauguuc uccaugcagu      540

cccuccuccc cgaccucccc cucgaggccu ggcccgccac cgacaagacc aagcgcgagg      600

aggucgacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  6439
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt2)

<400>  6439
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuucgc cugccuccuc ggcgccuccc      120

ucgccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccuacacc uccuacggcu      240

acgagcccau gggcggcugg cuccaccacc agaucauccc cgucgucucc cagcagaccc      300

cccaguccca cgcccuccag ccccaccacc acauccccau gguccccgcc cagcagcccg      360

gcauccccca gcagcccaug augccccucc ccggccagca cuccaugacc cccacccagc      420

accaccagcc caaccucccc cuccccgccc agcagcccuu ccagccccag cccguccagc      480

cccagcccca ccagccccuc cagccccagu cccccaugca ccccauccag ccccuccucc      540

cccagccccc ccuccccccc auguucucca ugcagucccu ccuccccgac cucccccucg      600

aggccuggcc cgccaccgac aagaccaagc gcgaggaggu cgacugagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6440
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt2)

<400>  6440
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccucccuc cuccccgacc      240

ucccccucga ggccuggccc gccaccgaca agaccaagcg cgaggagguc gacugaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  6441
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt2)

<400>  6441
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

accucuaccu cgaggccauc cgcaucgacc gcaccgccuu cguccucacc ccccucaagu      240

gguaccagaa caugauccgc caccccuaca ccuccuacgg cuacgagccc augggcggcu      300

ggcuccacca ccagaucauc cccgucgucu cccagcagac cccccagucc cacgcccucc      360

agccccacca ccacaucccc augguccccg cccagcagcc cggcaucccc cagcagccca      420

ugaugccccu ccccggccag cacuccauga cccccaccca gcaccaccag cccaaccucc      480

cccuccccgc ccagcagccc uuccagcccc agcccgucca gccccagccc caccagcccc      540

uccagcccca gucccccaug caccccaucc agccccuccu cccccagccc ccccuccccc      600

ccauguucuc caugcagucc cuccuccccg accucccccu cgaggccugg cccgccaccg      660

acaagaccaa gcgcgaggag gucgacugag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  6442
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt2)

<400>  6442
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgagg      180

uccucacccc ccucaagugg uaccagaaca ugauccgcca ccccaccccc cagucccacg      240

cccuccagcc ccaccaccac auccccaugg uccccgccca gcagcccggc aucccccagc      300

agcccaugau gccccucccc ggccagcacu ccaugacccc cacccagcac caccagccca      360

accucccccu ccccgcccag cagcccuucc agccccagcc cguccagccc cagccccacc      420

agccccucca gccccagucc cccaugcacc ccauccagcc ccuccucccc cagccccccc      480

ucccccccau guucuccaug cagucccucc uccccgaccu cccccucgag gccuggcccg      540

ccaccgacaa gaccaagcgc gaggaggucg acugaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  6443
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt2)

<400>  6443
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga gguccucacc ccccucaagu gguaccagaa caugauccgc caccccuaca      180

ccuccuacgg cuacgagccc augggcggcu ggcuccacca ccagaucauc cccgucgucu      240

cccagcagac cccccagucc cacgcccucc agccccacca ccacaucccc augguccccg      300

cccagcagcc cggcaucccc cagcagccca ugaugccccu ccccggccag cacuccauga      360

cccccaccca gcaccaccag cccaaccucc cccuccccgc ccagcagccc uuccagcccc      420

agcccgucca gccccagccc caccagcccc uccagcccca gucccccaug caccccaucc      480

agccccuccu cccccagccc ccccuccccc ccauguucuc caugcagucc cuccuccccg      540

accucccccu cgaggccugg cccgccaccg acaagaccaa gcgcgaggag gucgacugag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  6444
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt2)

<400>  6444
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgucg cccgccuccc ccuccuccuc ggccuccucc      120

uccucccccg ccccggccgc ccccucgacc ucgccgacua caccuacgac cucgccgagg      180

aggacgacuc cgagccccuc aacuacaagg accccugcaa ggccgccgcc uuccucggcg      240

acaucgcccu cgacgaggag gaccuccgcg ccuuccaggu ccagcaggcc gucgaccucc      300

gccgccacac cgcccgcaag uccuccauca aggccgccgu ccccggcaac accuccaccc      360

ccuccugcca guccaccaac ggccagcccc agcgcggcgc cugcggccgc uggcgcggcc      420

gcucccgcuc ccgccgcgcc gccaccuccc gccccgagcg cgucuggccc gacggcguca      480

uccccuucgu caucggcggc aacuucaccg gcucccagcg cgccgucuuc cgccaggcca      540

ugcgccacug ggagaagcac accugcguca ccuuccucga gcgcaccgac gaggacuccu      600

acaucgucuu caccuaccgc cccugcggcu gcugcuccua cgucggccgc cgcggcggcg      660

gcccccaggc caucuccauc ggcaagaacu gcgacaaguu cggcaucguc guccacgagc      720

ucggccacgu cgucggcuuc uggcacgagc acacccgccc cgaccgcgac cgccacgucu      780

ccaucguccg cgagaacauc cagcccggcc aggaguacaa cuuccucaag auggagcccc      840

aggaggucga gucccucggc gagaccuacg acuucgacuc caucaugcac uacgcccgca      900

acaccuucuc ccgcggcauc uuccucgaca ccaucguccc caaguacgag gucaacggcg      960

ucaagccccc caucggccag cgcacccgcc ucuccaaggg cgacaucgcc caggcccgca     1020

agcucuacaa gugccccgcc ugcggcgaga cccuccagga cuccaccggc aacuucuccu     1080

cccccgagua ccccaacggc uacuccgccc acaugcacug cgucuggcgc aucuccguca     1140

cccccggcga gaagaucauc cucaacuuca ccucccucga ccucuaccgc ucccgccucu     1200

gcugguacga cuacgucgag guccgcgacg gcuucuggcg caaggccccc cuccgcggcc     1260

gcuucugcgg cuccaagcuc cccgagccca ucgucuccac cgacucccgc cucugggucg     1320

aguuccgcuc cuccuccaac ugggucggca agggcuucuu cgccgucuac gaggccaucu     1380

gcggcggcga cgucaagaag gacuacggcc acauccaguc ccccaacuac cccgacgacu     1440

accgccccuc caaggucugc aucuggcgca uccaggucuc cgagggcuuc cacgucggcc     1500

ucaccuucca guccuucgag aucgagcgcc acgacuccug cgccuacgac uaccucgagg     1560

uccgcgacgg ccacuccgag uccuccaccc ucaucggccg cuacugcggc uacgagaagc     1620

ccgacgacau caaguccacc uccucccgcc ucuggcucaa guucgucucc gacggcucca     1680

ucaacaaggc cggcuucgcc gucaacuucu ucaaggaggu cgacgagugc ucccgcccca     1740

accgcggcgg cugcgagcag cgcugccuca acacccucgg cuccuacaag ugcuccugcg     1800

accccggcua cgagcucgcc cccgacaagc gccgcugcga ggccgccugc ggcggcuucc     1860

ucaccaagcu caacggcucc aucaccuccc ccggcuggcc caaggaguac ccccccaaca     1920

agaacugcau cuggcagcuc gucgccccca cccaguaccg caucucccuc caguucgacu     1980

ucuucgagac cgagggcaac gacgucugca aguacgacuu cgucgagguc cgcuccggcc     2040

ucaccgccga cuccaagcuc cacggcaagu ucugcggcuc cgagaagccc gaggucauca     2100

ccucccagua caacaacaug cgcgucgagu ucaaguccga caacaccguc uccaagaagg     2160

gcuucaaggc ccacuucuuc uccgacaagg acgagugcuc caaggacaac ggcggcugcc     2220

agcaggacug cgucaacacc uucggcuccu acgagugcca gugccgcucc ggcuucgucc     2280

uccacgacaa caagcacgac ugcaaggagg ccggcugcga ccacaagguc accuccaccu     2340

ccggcaccau caccuccccc aacuggcccg acaaguaccc cuccaagaag gagugcaccu     2400

gggccaucuc cuccaccccc ggccaccgcg ucaagcucac cuucauggag auggacaucg     2460

agucccagcc cgagugcgcc uacgaccacc ucgaggucuu cgacggccgc gacgccaagg     2520

cccccguccu cggccgcuuc ugcggcucca agaagcccga gcccguccuc gccaccggcu     2580

cccgcauguu ccuccgcuuc uacuccgaca acuccgucca gcgcaagggc uuccaggccu     2640

cccacgccac cgagugcggc ggccaggucc gcgccgacgu caagaccaag gaccucuacu     2700

cccacgccca guucggcgac aacaacuacc ccggcggcgu cgacugcgag ugggucaucg     2760

ucgccgagga gggcuacggc gucgagcucg ucuuccagac cuucgagguc gaggaggaga     2820

ccgacugcgg cuacgacuac auggagcucu ucgacggcua cgacuccacc gccccccgcc     2880

ucggccgcua cugcggcucc ggcccccccg aggaggucua cuccgccggc gacuccgucc     2940

ucgucaaguu ccacuccgac gacaccauca ccaagaaggg cuuccaccuc cgcuacaccu     3000

ccaccaaguu ccaggacacc cuccacuccc gcaagugagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  6445
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt2)

<400>  6445
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgccggca cccgcugccu ccucgcccuc cuccuccccc      120

agguccuccu cggcggcgcc gccggccucg uccccgagcu cggccgccgc aaguucgccg      180

ccgccuccuc cggccgcccc uccucccagc ccuccgacga gguccucucc gaguucgagc      240

uccgccuccu cuccauguuc ggccucaagc agcgccccac ccccucccgc gacgccgucg      300

ucccccccua caugcucgac cucuaccgcc gccacuccgg ccagcccggc ucccccgccc      360

ccgaccaccg ccucgagcgc gccgccuccc gcgccaacac cguccgcucc uuccaccacg      420

aggagucccu cgaggagcuc cccgagaccu ccggcaagac cacccgccgc uucuucuuca      480

accucuccuc cauccccacc gaggaguuca ucaccuccgc cgagcuccag gucuuccgcg      540

agcagaugca ggacgcccuc ggcaacaacu ccuccuucca ccaccgcauc aacaucuacg      600

agaucaucaa gcccgccacc gccaacucca aguuccccgu cacccgccuc cucgacaccc      660

gccucgucaa ccagaacgcc ucccgcuggg aguccuucga cgucaccccc gccgucaugc      720

gcuggaccgc ccagggccac gccaaccacg gcuucgucgu cgaggucgcc caccucgagg      780

agaagcaggg cgucuccaag cgccacgucc gcaucucccg cucccuccac caggacgagc      840

acuccugguc ccagauccgc ccccuccucg ucaccuucgg ccacgacggc aagggccacc      900

cccuccacaa gcgcgagaag cgccaggcca agcacaagca gcgcaagcgc cucaaguccu      960

ccugcaagcg ccacccccuc uacgucgacu ucuccgacgu cggcuggaac gacuggaucg     1020

ucgccccccc cggcuaccac gccuucuacu gccacggcga gugccccuuc ccccucgccg     1080

accaccucaa cuccaccaac cacgccaucg uccagacccu cgucaacucc gucaacucca     1140

agauccccaa ggccugcugc guccccaccg agcucuccgc caucuccaug cucuaccucg     1200

acgagaacga gaaggucguc cucaagaacu accaggacau ggucgucgag ggcugcggcu     1260

gccgcugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  6446
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt2)

<400>  6446
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auccccggca accgcaugcu cauggucguc cuccucugcc      120

agguccuccu cggcggcgcc ucccacgccu cccucauccc cgagaccggc aagaagaagg      180

ucgccgagau ccagggccac gccggcggcc gccgcuccgg ccagucccac gagcuccucc      240

gcgacuucga ggccacccuc cuccagaugu ucggccuccg ccgccgcccc cagcccucca      300

aguccgccgu cauccccgac uacaugcgcg accucuaccg ccuccagucc ggcgaggagg      360

aggaggagca gauccacucc accggccucg aguaccccga gcgccccgcc ucccgcgcca      420

acaccguccg cuccuuccac cacgaggagc accucgagaa cauccccggc accuccgaga      480

acuccgccuu ccgcuuccuc uucaaccucu ccuccauccc cgagaacgag gucaucuccu      540

ccgccgagcu ccgccucuuc cgcgagcagg ucgaccaggg ccccgacugg gagcgcggcu      600

uccaccgcau caacaucuac gaggucauga agccccccgc cgaggucguc cccggccacc      660

ucaucacccg ccuccucgac acccgccucg uccaccacaa cgucacccgc ugggagaccu      720

ucgacgucuc ccccgccguc cuccgcugga cccgcgagaa gcagcccaac uacggccucg      780

ccaucgaggu cacccaccuc caccagaccc gcacccacca gggccagcac guccgcaucu      840

cccgcucccu cccccagggc uccggcaacu gggcccagcu ccgcccccuc cucgucaccu      900

ucggccacga cggccgcggc cacgcccuca cccgccgccg ccgcgccaag cgcuccccca      960

agcaccacuc ccagcgcgcc cgcaagaaga acaagaacug ccgccgccac ucccucuacg     1020

ucgacuucuc cgacgucggc uggaacgacu ggaucgucgc cccccccggc uaccaggccu     1080

ucuacugcca cggcgacugc cccuuccccc ucgccgacca ccucaacucc accaaccacg     1140

ccaucgucca gacccucguc aacuccguca acuccuccau ccccaaggcc ugcugcgucc     1200

ccaccgagcu cuccgccauc uccaugcucu accucgacga guacgacaag gucguccuca     1260

agaacuacca ggagaugguc gucgagggcu gcggcugccg cugaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  6447
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt2)

<400>  6447
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggccucg gccgccgcgc ccaguggcuc ugcugguggu      120

ggggccuccu cugcuccugc ugcggccccc ccccccuccg ccccccccuc cccgccgccg      180

ccgccgccgc cgccggcggc cagcuccucg gcgacggcgg cucccccggc cgcaccgagc      240

agcccccccc cuccccccag uccuccuccg gcuuccucua ccgccgccuc aagacccagg      300

agaagcgcga gaugcagaag gagauccucu ccguccucgg ccucccccac cgcccccgcc      360

cccuccacgg ccuccagcag ccccagcccc ccgcccuccg ccagcaggag gagcagcagc      420

agcagcagca gcucccccgc ggcgagcccc cccccggccg ccucaagucc gccccccucu      480

ucaugcucga ccucuacaac gcccucuccg ccgacaacga cgaggacggc gccuccgagg      540

gcgagcgcca gcaguccugg ccccacgagg ccgccuccuc cucccagcgc cgccagcccc      600

cccccggcgc cgcccacccc cucaaccgca agucccuccu cgcccccggc uccggcuccg      660

gcggcgccuc cccccucacc uccgcccagg acuccgccuu ccucaacgac gccgacaugg      720

ucauguccuu cgucaaccuc gucgaguacg acaaggaguu cuccccccgc cagcgccacc      780

acaaggaguu caaguucaac cucucccaga uccccgaggg cgaggucguc accgccgccg      840

aguuccgcau cuacaaggac ugcgucaugg gcuccuucaa gaaccagacc uuccucaucu      900

ccaucuacca gguccuccag gagcaccagc accgcgacuc cgaccucuuc cuccucgaca      960

cccgcgucgu cugggccucc gaggagggcu ggcucgaguu cgacaucacc gccaccucca     1020

accucugggu cgucaccccc cagcacaaca ugggccucca gcucuccguc gucacccgcg     1080

acggcgucca cguccacccc cgcgccgccg gccucgucgg ccgcgacggc cccuacgaca     1140

agcagcccuu cauggucgcc uucuucaagg ucuccgaggu ccacguccgc accacccgcu     1200

ccgccuccuc ccgccgccgc cagcaguccc gcaaccgcuc cacccagucc caggacgucg     1260

cccgcgucuc cuccgccucc gacuacaacu ccuccgagcu caagaccgcc ugccgcaagc     1320

acgagcucua cgucuccuuc caggaccucg gcuggcagga cuggaucauc gcccccaagg     1380

gcuacgccgc caacuacugc gacggcgagu gcuccuuccc ccucaacgcc cacaugaacg     1440

ccaccaacca cgccaucguc cagacccucg uccaccucau gaaccccgag uacgucccca     1500

agcccugcug cgcccccacc aagcucaacg ccaucuccgu ccucuacuuc gacgacaacu     1560

ccaacgucau ccucaagaag uaccgcaaca uggucguccg cgccugcggc ugccacugag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  6448
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt2)

<400>  6448
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacguccgcu cccuccgcgc cgccgccccc cacuccuucg      120

ucgcccucug ggccccccuc uuccuccucc gcuccgcccu cgccgacuuc ucccucgaca      180

acgaggucca cuccuccuuc auccaccgcc gccuccgcuc ccaggagcgc cgcgagaugc      240

agcgcgagau ccucuccauc cucggccucc cccaccgccc ccgcccccac cuccagggca      300

agcacaacuc cgcccccaug uucaugcucg accucuacaa cgccauggcc gucgaggagg      360

gcggcggccc cggcggccag ggcuucuccu accccuacaa ggccgucuuc uccacccagg      420

gccccccccu cgccucccuc caggacuccc acuuccucac cgacgccgac auggucaugu      480

ccuucgucaa ccucgucgag cacgacaagg aguucuucca cccccgcuac caccaccgcg      540

aguuccgcuu cgaccucucc aagauccccg agggcgaggc cgucaccgcc gccgaguucc      600

gcaucuacaa ggacuacauc cgcgagcgcu ucgacaacga gaccuuccgc aucuccgucu      660

accagguccu ccaggagcac cucggccgcg aguccgaccu cuuccuccuc gacucccgca      720

cccucugggc cuccgaggag ggcuggcucg ucuucgacau caccgccacc uccaaccacu      780

gggucgucaa cccccgccac aaccucggcc uccagcucuc cgucgagacc cucgacggcc      840

aguccaucaa ccccaagcuc gccggccuca ucggccgcca cggcccccag aacaagcagc      900

ccuucauggu cgccuucuuc aaggccaccg agguccacuu ccgcuccauc cgcuccaccg      960

gcuccaagca gcgcucccag aaccgcucca agacccccaa gaaccaggag gcccuccgca     1020

uggccaacgu cgccgagaac uccuccuccg accagcgcca ggccugcaag aagcacgagc     1080

ucuacgucuc cuuccgcgac cucggcuggc aggacuggau caucgccccc gagggcuacg     1140

ccgccuacua cugcgagggc gagugcgccu ucccccucaa cuccuacaug aacgccacca     1200

accacgccau cguccagacc cucguccacu ucaucaaccc cgagaccguc cccaagcccu     1260

gcugcgcccc cacccagcuc aacgccaucu ccguccucua cuucgacgac uccuccaacg     1320

ucauccucaa gaaguaccgc aacauggucg uccgcgccug cggcugccac ugaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  6449
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt2)

<400>  6449
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggccuccg ccgcccuccu cugccuccuc cucaccgccg      120

ccgccuucuc cccccagggc cucgcccagc ccgucggcau caacaccucc accaccugcu      180

gcuaccgcuu caucaacaag aagaucccca agcagcgccu cgaguccuac cgccgcacca      240

ccuccuccca cugcccccgc gaggccguca ucuucaagac caagcucgac aaggagaucu      300

gcgccgaccc cacccagaag uggguccagg acuucaugaa gcaccucgac aagaagaccc      360

agacccccaa gcucugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  6450
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt2)

<400>  6450
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuccucaccc ucaucauccu ccuccccguc gucuccaagu      120

ucuccuucgu cucccucucc gccccccagc acugguccug ccccgagggc acccucgccg      180

gcaacggcaa cuccaccugc gucggccccg cccccuuccu caucuucucc cacggcaacu      240

ccaucuuccg caucgacacc gagggcacca acuacgagca gcucgucguc gacgccggcg      300

ucuccgucau cauggacuuc cacuacaacg agaagcgcau cuacuggguc gaccucgagc      360

gccagcuccu ccagcgcguc uuccucaacg gcucccgcca ggagcgcguc ugcaacaucg      420

agaagaacgu cuccggcaug gccaucaacu ggaucaacga ggaggucauc ugguccaacc      480

agcaggaggg caucaucacc gucaccgaca ugaagggcaa caacucccac auccuccucu      540

ccgcccucaa guaccccgcc aacgucgccg ucgaccccgu cgagcgcuuc aucuucuggu      600

ccuccgaggu cgccggcucc cucuaccgcg ccgaccucga cggcgucggc gucaaggccc      660

uccucgagac cuccgagaag aucaccgccg ucucccucga cguccucgac aagcgccucu      720

ucuggaucca guacaaccgc gagggcucca acucccucau cugcuccugc gacuacgacg      780

gcggcuccgu ccacaucucc aagcacccca cccagcacaa ccucuucgcc augucccucu      840

ucggcgaccg caucuucuac uccaccugga agaugaagac caucuggauc gccaacaagc      900

acaccggcaa ggacaugguc cgcaucaacc uccacuccuc cuucgucccc cucggcgagc      960

ucaaggucgu ccacccccuc gcccagccca aggccgagga cgacaccugg gagcccgagc     1020

agaagcucug caagcuccgc aagggcaacu gcuccuccac cgucugcggc caggaccucc     1080

agucccaccu cugcaugugc gccgagggcu acgcccucuc ccgcgaccgc aaguacugcg     1140

aggacgucaa cgagugcgcc uucuggaacc acggcugcac ccucggcugc aagaacaccc     1200

ccggcuccua cuacugcacc ugccccgucg gcuucguccu ccuccccgac ggcaagcgcu     1260

gccaccagcu cgucuccugc ccccgcaacg ucuccgagug cucccacgac ugcguccuca     1320

ccuccgaggg cccccucugc uucugccccg agggcuccgu ccucgagcgc gacggcaaga     1380

ccugcuccgg cugcuccucc cccgacaacg gcggcugcuc ccagcucugc gucccccucu     1440

cccccgucuc cugggagugc gacugcuucc ccggcuacga ccuccagcuc gacgagaagu     1500

ccugcgccgc cuccggcccc cagcccuucc uccucuucgc caacucccag gacauccgcc     1560

acaugcacuu cgacggcacc gacuacggca cccuccucuc ccagcagaug ggcauggucu     1620

acgcccucga ccacgacccc gucgagaaca agaucuacuu cgcccacacc gcccucaagu     1680

ggaucgagcg cgccaacaug gacggcuccc agcgcgagcg ccucaucgag gagggcgucg     1740

acguccccga gggccucgcc gucgacugga ucggccgccg cuucuacugg accgaccgcg     1800

gcaagucccu caucggccgc uccgaccuca acggcaagcg cuccaagauc aucaccaagg     1860

agaacaucuc ccagccccgc ggcaucgccg uccaccccau ggccaagcgc cucuucugga     1920

ccgacaccgg caucaacccc cgcaucgagu ccuccucccu ccagggccuc ggccgccucg     1980

ucaucgccuc cuccgaccuc aucuggcccu ccggcaucac caucgacuuc cucaccgaca     2040

agcucuacug gugcgacgcc aagcaguccg ucaucgagau ggccaaccuc gacggcucca     2100

agcgccgccg ccucacccag aacgacgucg gccaccccuu cgccgucgcc gucuucgagg     2160

acuacgucug guucuccgac ugggccaugc ccuccgucau gcgcgucaac aagcgcaccg     2220

gcaaggaccg cguccgccuc cagggcucca ugcucaagcc cuccucccuc gucgucgucc     2280

acccccucgc caagcccggc gccgaccccu gccucuacca gaacggcggc ugcgagcaca     2340

ucugcaagaa gcgccucggc accgccuggu gcuccugccg cgagggcuuc augaaggccu     2400

ccgacggcaa gaccugccuc gcccucgacg gccaccagcu ccucgccggc ggcgaggucg     2460

accucaagaa ccaggucacc ccccucgaca uccucuccaa gacccgcguc uccgaggaca     2520

acaucaccga gucccagcac augcucgucg ccgagaucau ggucuccgac caggacgacu     2580

gcgcccccgu cggcugcucc auguacgccc gcugcaucuc cgagggcgag gacgccaccu     2640

gccagugccu caagggcuuc gccggcgacg gcaagcucug cuccgacauc gacgagugcg     2700

agaugggcgu ccccgucugc ccccccgccu ccuccaagug caucaacacc gagggcggcu     2760

acgucugccg cugcuccgag ggcuaccagg gcgacggcau ccacugccuc gacaucgacg     2820

agugccagcu cggcgagcac uccugcggcg agaacgccuc cugcaccaac accgagggcg     2880

gcuacaccug caugugcgcc ggccgccucu ccgagcccgg ccucaucugc cccgacucca     2940

cccccccccc ccaccuccgc gaggacgacc accacuacuc cguccgcaac uccgacuccg     3000

agugcccccu cucccacgac ggcuacugcc uccacgacgg cgucugcaug uacaucgagg     3060

cccucgacaa guacgccugc aacugcgucg ucggcuacau cggcgagcgc ugccaguacc     3120

gcgaccucaa guggugggag cuccgccacg ccggccacgg ccagcagcag aaggucaucg     3180

ucgucgccgu cugcgucguc guccucguca ugcuccuccu ccucucccuc uggggcgccc     3240

acuacuaccg cacccagaag cuccucucca agaaccccaa gaaccccuac gaggaguccu     3300

cccgcgacgu ccgcucccgc cgccccgccg acaccgagga cggcaugucc uccugccccc     3360

agcccugguu cgucgucauc aaggagcacc aggaccucaa gaacggcggc cagcccgucg     3420

ccggcgagga cggccaggcc gccgacggcu ccaugcagcc caccuccugg cgccaggagc     3480

cccagcucug cggcaugggc accgagcagg gcugcuggau ccccgucucc uccgacaagg     3540

gcuccugccc ccaggucaug gagcgcuccu uccacaugcc cuccuacggc acccagaccc     3600

ucgagggcgg cgucgagaag ccccacuccc uccucuccgc caacccccuc uggcagcagc     3660

gcgcccucga ccccccccac cagauggagc ucacccagug aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  6451
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt2)

<400>  6451
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggcc gccgcaugga gaugcucugc gccggccgcg      120

uccccgcccu ccuccucugc cucggcuucc accuccucca ggccguccuc uccaccaccg      180

ucauccccuc cugcaucccc ggcgaguccu ccgacaacug caccgcccuc guccagaccg      240

aggacaaccc ccgcgucgcc caggucucca ucaccaagug cuccuccgac augaacggcu      300

acugccucca cggccagugc aucuaccucg ucgacauguc ccagaacuac ugccgcugcg      360

aggucggcua caccggcguc cgcugcgagc acuucuuccu caccguccac cagccccucu      420

ccaaggagua cgucgcccuc accgucaucc ucaucauccu cuuccucauc accgucgucg      480

gcuccaccua cuacuucugc cgcugguacc gcaaccgcaa guccaaggag cccaagaagg      540

aguacgagcg cgucaccucc ggcgaccccg agcuccccca ggucugagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  6452
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt2)

<400>  6452
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgagggcg agaucaccac cuucaccgcc cucaccgaga      120

aguucaaccu cccccccggc aacuacaaga agcccaagcu ccucuacugc uccaacggcg      180

gccacuuccu ccgcauccuc cccgacggca ccgucgacgg cacccgcgac cgcuccgacc      240

agcacaucca gcuccagcuc uccgccgagu ccgucggcga ggucuacauc aaguccaccg      300

agaccggcca guaccucgcc auggacaccg acggccuccu cuacggcucc cagaccccca      360

acgaggagug ccucuuccuc gagcgccucg aggagaacca cuacaacacc uacaucucca      420

agaagcacgc cgagaagaac ugguucgucg gccucaagaa gaacggcucc ugcaagcgcg      480

gcccccgcac ccacuacggc cagaaggcca uccucuuccu cccccucccc gucuccuccg      540

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  6453
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt2)

<400>  6453
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucggcgucg gcggcggcga cgucgaggac gucacccccc      120

gccccggcgg cugccagauc uccggccgcg gcgcccgcgg cugcaacggc auccccggcg      180

ccgccgccug ggaggccgcc cucccccgcc gccgcccccg ccgccacccc uccgucaacc      240

cccgcucccg cgccgccggc uccccccgca cccgcggccg ccgcaccgag gagcgccccu      300

ccggcucccg ccucggcgac cgcggccgcg gccgcgcccu ccccggcggc cgccucggcg      360

gccgcggccg cggccgcgcc cccgagcgcg ucggcggccg cggccgcggc cgcggcaccg      420

ccgccccccg cgccgccccc gccgcccgcg gcucccgccc cggccccgcc ggcaccaugg      480

ccgccggcuc caucaccacc cuccccgccc uccccgagga cggcggcucc ggcgccuucc      540

cccccggcca cuucaaggac cccaagcgcc ucuacugcaa gaacggcggc uucuuccucc      600

gcauccaccc cgacggccgc gucgacggcg uccgcgagaa guccgacccc cacaucaagc      660

uccagcucca ggccgaggag cgcggcgucg ucuccaucaa gggcgucugc gccaaccgcu      720

accucgccau gaaggaggac ggccgccucc ucgccuccaa gugcgucacc gacgagugcu      780

ucuucuucga gcgccucgag uccaacaacu acaacaccua ccgcucccgc aaguacaccu      840

ccugguacgu cgcccucaag cgcaccggcc aguacaagcu cggcuccaag accggccccg      900

gccagaaggc cauccucuuc cuccccaugu ccgccaaguc cugaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  6454
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt2)

<400>  6454
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uccucaccug gauccucccc acccuccucu      120

accgcuccug cuuccacauc aucugccucg ucggcaccau cucccucgcc ugcaacgaca      180

ugacccccga gcagauggcc accaacguca acugcuccuc ccccgagcgc cacacccgcu      240

ccuacgacua cauggagggc ggcgacaucc gcguccgccg ccucuucugc cgcacccagu      300

gguaccuccg caucgacaag cgcggcaagg ucaagggcac ccaggagaug aagaacaacu      360

acaacaucau ggagauccgc accgucgccg ucggcaucgu cgccaucaag ggcgucgagu      420

ccgaguucua ccucgccaug aacaaggagg gcaagcucua cgccaagaag gagugcaacg      480

aggacugcaa cuucaaggag cucauccucg agaaccacua caacaccuac gccuccgcca      540

aguggaccca caacggcggc gagauguucg ucgcccucaa ccagaagggc auccccgucc      600

gcggcaagaa gaccaagaag gagcagaaga ccgcccacuu ccuccccaug gccaucaccu      660

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  6455
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt2)

<400>  6455
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcuccucc ccuccgucgu ccucaagcuc uuccucgccg      120

ccguccucuc cgcccucguc accggcgagu cccucgagcg ccuccgccgc ggccucgccg      180

ccggcaccuc caaccccgac ccccccaccg ucuccaccga ccagcuccuc ccccucggcg      240

gcggccgcga ccgcaagguc cgcgaccucc aggaggccga ccucgaccuc cuccgcguca      300

cccucuccuc caagccccag gcccucgcca cccccaacaa ggaggagcac ggcaagcgca      360

agaagaaggg caagggccuc ggcaagaagc gcgaccccug ccuccgcaag uacaaggacu      420

ucugcaucca cggcgagugc aaguacguca aggagcuccg cgcccccucc ugcaucugcc      480

accccggcua ccacggcgag cgcugccacg gccucucccu ccccgucgag aaccgccucu      540

acaccuacga ccacaccacc auccucgccg ucgucgccgu cguccucucc uccgucugcc      600

uccucgucau cgucggccuc cucauguucc gcuaccaccg ccgcggcggc uacgacgucg      660

agaacgagga gaaggucaag cucggcauga ccaacuccca cugaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  6456
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt2)

<400>  6456
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggucacca agcuccuccc cgcccuccuc cuccagcacg      120

uccuccucca ccuccuccuc cuccccaucg ccauccccua cgccgagggc cagcgcaagc      180

gccgcaacac cauccacgag uucaagaagu ccgccaagac cacccucauc aagaucgacc      240

ccgcccucaa gaucaagacc aagaagguca acaccgccga ccagugcgcc aaccgcugca      300

cccgcaacaa gggccucccc uucaccugca aggccuucgu cuucgacaag gcccgcaagc      360

agugccucug guuccccuuc aacuccaugu ccuccggcgu caagaaggag uucggccacg      420

aguucgaccu cuacgagaac aaggacuaca uccgcaacug caucaucggc aagggccgcu      480

ccuacaaggg caccgucucc aucaccaagu ccggcaucaa gugccagccc ugguccucca      540

ugauccccca cgagcacucc uuccuccccu ccuccuaccg cggcaaggac cuccaggaga      600

acuacugccg caacccccgc ggcgaggagg gcggccccug gugcuucacc uccaaccccg      660

agguccgcua cgaggucugc gacauccccc agugcuccga ggucgagugc augaccugca      720

acggcgaguc cuaccgcggc cucauggacc acaccgaguc cggcaagauc ugccagcgcu      780

gggaccacca gaccccccac cgccacaagu uccuccccga gcgcuacccc gacaagggcu      840

ucgacgacaa cuacugccgc aaccccgacg gccagccccg ccccuggugc uacacccucg      900

acccccacac ccgcugggag uacugcgcca ucaagaccug cgccgacaac accaugaacg      960

acaccgacgu cccccucgag accaccgagu gcauccaggg ccagggcgag ggcuaccgcg     1020

gcaccgucaa caccaucugg aacggcaucc ccugccagcg cugggacucc caguaccccc     1080

acgagcacga caugaccccc gagaacuuca agugcaagga ccuccgcgag aacuacugcc     1140

gcaaccccga cggcuccgag ucccccuggu gcuucaccac cgaccccaac auccgcgucg     1200

gcuacugcuc ccagaucccc aacugcgaca ugucccacgg ccaggacugc uaccgcggca     1260

acggcaagaa cuacaugggc aaccucuccc agacccgcuc cggccucacc ugcuccaugu     1320

gggacaagaa cauggaggac cuccaccgcc acaucuucug ggagcccgac gccuccaagc     1380

ucaacgagaa cuacugccgc aaccccgacg acgacgccca cggccccugg ugcuacaccg     1440

gcaacccccu cauccccugg gacuacugcc ccaucucccg cugcgagggc gacaccaccc     1500

ccaccaucgu caaccucgac caccccguca ucuccugcgc caagaccaag cagcuccgcg     1560

ucgucaacgg cauccccacc cgcaccaaca ucggcuggau ggucucccuc cgcuaccgca     1620

acaagcacau cugcggcggc ucccucauca aggaguccug gguccucacc gcccgccagu     1680

gcuuccccuc ccgcgaccuc aaggacuacg aggccuggcu cggcauccac gacguccacg     1740

gccgcggcga cgagaagugc aagcaggucc ucaacgucuc ccagcucguc uacggccccg     1800

agggcuccga ccucguccuc augaagcucg cccgccccgc cguccucgac gacuucgucu     1860

ccaccaucga ccuccccaac uacggcugca ccauccccga gaagaccucc ugcuccgucu     1920

acggcugggg cuacaccggc cucaucaacu acgacggccu ccuccgcguc gcccaccucu     1980

acaucauggg caacgagaag ugcucccagc accaccgcgg caaggucacc cucaacgagu     2040

ccgagaucug cgccggcgcc gagaagaucg gcuccggccc cugcgagggc gacuacggcg     2100

gcccccucgu cugcgagcag cacaagaugc gcaugguccu cggcgucauc guccccggcc     2160

gcggcugcgc cauccccaac cgccccggca ucuucguccg cgucgccuac uacgccaagu     2220

ggauccacaa gaucauccuc accuacaagg ucccccaguc cugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  6457
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt2)

<400>  6457
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggccg ccgccaucgg caucgaccuc ggcaccaccu      120

acuccugcgu cggcgucuuc cagcacggca aggucgagau caucgccaac gaccagggca      180

accgcaccac ccccuccuac gucgccuuca ccgacaccga gcgccucauc ggcgacgccg      240

ccaagaacca ggucgcccuc aacccccaga acaccgucuu cgacgccaag cgccucaucg      300

gccgcaaguu cggcgacccc gucguccagu ccgacaugaa gcacuggccc uuccagguca      360

ucaacgacgg cgacaagccc aagguccagg ucuccuacaa gggcgagacc aaggccuucu      420

accccgagga gaucuccucc augguccuca ccaagaugaa ggagaucgcc gaggccuacc      480

ucggcuaccc cgucaccaac gccgucauca ccguccccgc cuacuucaac gacucccagc      540

gccaggccac caaggacgcc ggcgucaucg ccggccucaa cguccuccgc aucaucaacg      600

agcccaccgc cgccgccauc gccuacggcc ucgaccgcac cggcaagggc gagcgcaacg      660

uccucaucuu cgaccucggc ggcggcaccu ucgacgucuc cauccucacc aucgacgacg      720

gcaucuucga ggucaaggcc accgccggcg acacccaccu cggcggcgag gacuucgaca      780

accgccucgu caaccacuuc gucgaggagu ucaagcgcaa gcacaagaag gacaucuccc      840

agaacaagcg cgccguccgc cgccuccgca ccgccugcga gcgcgccaag cgcacccucu      900

ccuccuccac ccaggccucc cucgagaucg acucccucuu cgagggcauc gacuucuaca      960

ccuccaucac ccgcgcccgc uucgaggagc ucugcuccga ccucuuccgc uccacccucg     1020

agcccgucga gaaggcccuc cgcgacgcca agcucgacaa ggcccagauc cacgaccucg     1080

uccucgucgg cggcuccacc cgcaucccca agguccagaa gcuccuccag gacuucuuca     1140

acggccgcga ccucaacaag uccaucaacc ccgacgaggc cgucgccuac ggcgccgccg     1200

uccaggccgc cauccucaug ggcgacaagu ccgagaacgu ccaggaccuc cuccuccucg     1260

acgucgcccc ccucucccuc ggccucgaga ccgccggcgg cgucaugacc gcccucauca     1320

agcgcaacuc caccaucccc accaagcaga cccagaucuu caccaccuac uccgacaacc     1380

agcccggcgu ccucauccag gucuacgagg gcgagcgcgc caugaccaag gacaacaacc     1440

uccucggccg cuucgagcuc uccggcaucc cccccgcccc ccgcggcguc ccccagaucg     1500

aggucaccuu cgacaucgac gccaacggca uccucaacgu caccgccacc gacaagucca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg ccgccucucc aaggaggaga     1620

ucgagcgcau gguccaggag gccgagaagu acaaggccga ggacgagguc cagcgcgagc     1680

gcgucuccgc caagaacgcc cucgaguccu acgccuucaa caugaagucc gccgucgagg     1740

acgagggccu caagggcaag aucuccgagg ccgacaagaa gaagguccuc gacaagugcc     1800

aggaggucau cuccuggcuc gacgccaaca cccucgccga gaaggacgag uucgagcaca     1860

agcgcaagga gcucgagcag gucugcaacc ccaucaucuc cggccucuac cagggcgccg     1920

gcggccccgg ccccggcggc uucggcgccc agggccccaa gggcggcucc ggcuccggcc     1980

ccaccaucga ggaggucgac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6458
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt2)

<400>  6458
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggccg ccgccaucgg caucgaccuc ggcaccaccu      120

acuccugcgu cggcgucuuc cagcacggca aggucgagau caucgccaac gaccagggca      180

accgcaccac ccccuccuac gucgccuuca ccgacaccga gcgccucauc ggcgacgccg      240

ccaagaacca ggucgcccuc aacccccaga acaccgucuu cgacgccaag cgccucaucg      300

gccgcaaguu cggcgacccc gucguccagu ccgacaugaa gcacuggccc uuccagguca      360

ucaacgacgg cgacaagccc aagguccagg ucuccuacaa gggcgagacc aaggccuucu      420

accccgagga gaucuccucc augguccuca ccaagaugaa ggagaucgcc gaggccuacc      480

ucggcuaccc cgucaccaac gccgucauca ccguccccgc cuacuucaac gacucccagc      540

gccaggccac caaggacgcc ggcgucaucg ccggccucaa cguccuccgc aucaucaacg      600

agcccaccgc cgccgccauc gccuacggcc ucgaccgcac cggcaagggc gagcgcaacg      660

uccucaucuu cgaccucggc ggcggcaccu ucgacgucuc cauccucacc aucgacgacg      720

gcaucuucga ggucaaggcc accgccggcg acacccaccu cggcggcgag gacuucgaca      780

accgccucgu caaccacuuc gucgaggagu ucaagcgcaa gcacaagaag gacaucuccc      840

agaacaagcg cgccguccgc cgccuccgca ccgccugcga gcgcgccaag cgcacccucu      900

ccuccuccac ccaggccucc cucgagaucg acucccucuu cgagggcauc gacuucuaca      960

ccuccaucac ccgcgcccgc uucgaggagc ucugcuccga ccucuuccgc uccacccucg     1020

agcccgucga gaaggcccuc cgcgacgcca agcucgacaa ggcccagauc cacgaccucg     1080

uccucgucgg cggcuccacc cgcaucccca agguccagaa gcuccuccag gacuucuuca     1140

acggccgcga ccucaacaag uccaucaacc ccgacgaggc cgucgccuac ggcgccgccg     1200

uccaggccgc cauccucaug ggcgacaagu ccgagaacgu ccaggaccuc cuccuccucg     1260

acgucgcccc ccucucccuc ggccucgaga ccgccggcgg cgucaugacc gcccucauca     1320

agcgcaacuc caccaucccc accaagcaga cccagaucuu caccaccuac uccgacaacc     1380

agcccggcgu ccucauccag gucuacgagg gcgagcgcgc caugaccaag gacaacaacc     1440

uccucggccg cuucgagcuc uccggcaucc cccccgcccc ccgcggcguc ccccagaucg     1500

aggucaccuu cgacaucgac gccaacggca uccucaacgu caccgccacc gacaagucca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg ccgccucucc aaggaggaga     1620

ucgagcgcau gguccaggag gccgagaagu acaaggccga ggacgagguc cagcgcgagc     1680

gcgucuccgc caagaacgcc cucgaguccu acgccuucaa caugaagucc gccgucgagg     1740

acgagggccu caagggcaag aucuccgagg ccgacaagaa gaagguccuc gacaagugcc     1800

aggaggucau cuccuggcuc gacgccaaca cccucgccga gaaggacgag uucgagcaca     1860

agcgcaagga gcucgagcag gucugcaacc ccaucaucuc cggccucuac cagggcgccg     1920

gcggccccgg ccccggcggc uucggcgccc agggccccaa gggcggcucc ggcuccggcc     1980

ccaccaucga ggaggucgac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6459
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt2)

<400>  6459
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaccgcca agggcaucgc caucggcauc gaccucggca      120

ccaccuacuc cugcgucggc gucuuccagc acggcaaggu cgagaucauc gccaacgacc      180

agggcaaccg caccaccccc uccuacgucg ccuucaccga caccgagcgc cucaucggcg      240

acgccgccaa gaaccagguc gccaugaacc cccagaacac cgucuucgac gccaagcgcc      300

ucaucggccg caaguucaac gaccccgucg uccaggccga caugaagcuc uggcccuucc      360

aggucaucaa cgagggcggc aagcccaagg uccucgucuc cuacaagggc gagaacaagg      420

ccuucuaccc cgaggagauc uccuccaugg uccucaccaa gcucaaggag accgccgagg      480

ccuuccucgg ccaccccguc accaacgccg ucaucaccgu ccccgccuac uucaacgacu      540

cccagcgcca ggccaccaag gacgccggcg ucaucgccgg ccucaacguc cuccgcauca      600

ucaacgagcc caccgccgcc gccaucgccu acggccucga caagggcggc cagggcgagc      660

gccacguccu caucuucgac cucggcggcg gcaccuucga cgucuccauc cucaccaucg      720

acgacggcau cuucgagguc aaggccaccg ccggcgacac ccaccucggc ggcgaggacu      780

ucgacaaccg ccucgucucc cacuucgucg aggaguucaa gcgcaagcac aagaaggaca      840

ucucccagaa caagcgcgcc guccgccgcc uccgcaccgc cugcgagcgc gccaagcgca      900

cccucuccuc cuccacccag gccaaccucg agaucgacuc ccucuacgag ggcaucgacu      960

ucuacaccuc caucacccgc gcccgcuucg aggagcucug cgccgaccuc uuccgcggca     1020

cccucgagcc cgucgagaag gcccuccgcg acgccaagau ggacaaggcc aagauccacg     1080

acaucguccu cgucggcggc uccacccgca uccccaaggu ccagcgccuc cuccaggacu     1140

acuucaacgg ccgcgaccuc aacaagucca ucaaccccga cgaggccguc gccuacggcg     1200

ccgccgucca ggccgccauc cucaugggcg acaaguccga gaagguccag gaccuccucc     1260

uccucgacgu cgccccccuc ucccucggcc ucgagaccgc cggcggcguc augaccgccc     1320

ucaucaagcg caacuccacc auccccacca agcagaccca gaucuucacc accuacuccg     1380

acaaccagcc cggcguccuc auccaggucu acgagggcga gcgcgccaug accaaggaca     1440

acaaccuccu cggccgcuuc gaccucaccg gcaucccccc cgccccccgc ggcguccccc     1500

agaucgaggu caccuucgac aucgacgcca acggcauccu caacgucacc gccaccgaca     1560

aguccaccgg caaggucaac aagaucacca ucaccaacga caagggccgc cucuccaagg     1620

aggagaucga gcgcaugguc cucgacgccg agaaguacaa ggccgaggac gagguccagc     1680

gcgagaagau cgccgccaag aacgcccucg aguccuacgc cuucaacaug aaguccgucg     1740

ucuccgacga gggccucaag ggcaagaucu ccgaguccga caagaacaag auccucgaca     1800

agugcaacga gcuccucucc uggcucgagg ucaaccagcu cgccgagaag gacgaguucg     1860

accacaagcg caaggagcuc gagcagaugu gcaaccccau caucaccaag cucuaccagg     1920

gcggcugcac cggccccgcc ugcggcaccg gcuacguccc cggccgcccc gccaccggcc     1980

ccaccaucga ggaggucgac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6460
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt2)

<400>  6460
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgcccgcg gccccgccau cggcaucgac cucggcacca      120

ccuacuccug cgucggcguc uuccagcacg gcaaggucga gaucaucgcc aacgaccagg      180

gcaaccgcac cacccccucc uacgucgccu ucaccgacac cgagcgccuc aucggcgacg      240

ccgccaagaa ccaggucgcc augaacccca ccaacaccau cuucgacgcc aagcgccuca      300

ucggccgcaa guucgaggac gccaccgucc aguccgacau gaagcacugg cccuuccgcg      360

ucgucuccga gggcggcaag cccaaggucc aggucgagua caagggcgag accaagaccu      420

ucuuccccga ggagaucucc uccauggucc ucaccaagau gaaggagauc gccgaggccu      480

accucggcgg caagguccac uccgccguca ucaccguccc cgccuacuuc aacgacuccc      540

agcgccaggc caccaaggac gccggcacca ucaccggccu caacguccuc cgcaucauca      600

acgagcccac cgccgccgcc aucgccuacg gccucgacaa gaagggcugc gccggcggcg      660

agaagaacgu ccucaucuuc gaccucggcg gcggcaccuu cgacgucucc auccucacca      720

ucgaggacgg caucuucgag gucaagucca ccgccggcga cacccaccuc ggcggcgagg      780

acuucgacaa ccgcaugguc ucccaccucg ccgaggaguu caagcgcaag cacaagaagg      840

acaucggccc caacaagcgc gccguccgcc gccuccgcac cgccugcgag cgcgccaagc      900

gcacccucuc cuccuccacc caggccucca ucgagaucga cucccucuac gagggcgucg      960

acuucuacac cuccaucacc cgcgcccgcu ucgaggagcu caacgccgac cucuuccgcg     1020

gcacccucga gcccgucgag aaggcccucc gcgacgccaa gcucgacaag ggccagaucc     1080

aggagaucgu ccucgucggc ggcuccaccc gcauccccaa gauccagaag cuccuccagg     1140

acuucuucaa cggcaaggag cucaacaagu ccaucaaccc cgacgaggcc gucgccuacg     1200

gcgccgccgu ccaggccgcc auccucaucg gcgacaaguc cgagaacguc caggaccucc     1260

uccuccucga cgucaccccc cucucccucg gcaucgagac cgccggcggc gucaugaccc     1320

cccucaucaa gcgcaacacc accaucccca ccaagcagac ccagaccuuc accaccuacu     1380

ccgacaacca guccuccguc cucguccagg ucuacgaggg cgagcgcgcc augaccaagg     1440

acaacaaccu ccucggcaag uucgaccuca ccggcauccc ccccgccccc cgcggcgucc     1500

cccagaucga ggucaccuuc gacaucgacg ccaacggcau ccucaacguc accgccgccg     1560

acaaguccac cggcaaggag aacaagauca ccaucaccaa cgacaagggc cgccucucca     1620

aggacgacau cgaccgcaug guccaggagg ccgagcgcua caaguccgag gacgaggcca     1680

accgcgaccg cgucgccgcc aagaacgccc ucgaguccua caccuacaac aucaagcaga     1740

ccgucgagga cgagaagcuc cgcggcaaga ucuccgagca ggacaagaac aagauccucg     1800

acaagugcca ggaggucauc aacuggcucg accgcaacca gauggccgag aaggacgagu     1860

acgagcacaa gcagaaggag cucgagcgcg ucugcaaccc caucaucucc aagcucuacc     1920

agggcggccc cggcggcggc uccggcggcg gcggcuccgg cgccuccggc ggccccacca     1980

ucgaggaggu cgacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  6461
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt2)

<400>  6461
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgucgucg gcaucgaccu cggcuuccag uccugcuacg      120

ucgccgucgc ccgcgccggc ggcaucgaga ccaucgccaa cgaguacucc gaccgcugca      180

cccccgccug caucuccuuc ggccccaaga accgcuccau cggcgccgcc gccaaguccc      240

aggucaucuc caacgccaag aacaccgucc agggcuucaa gcgcuuccac ggccgcgccu      300

ucuccgaccc cuucgucgag gccgagaagu ccaaccucgc cuacgacauc guccagcucc      360

ccaccggccu caccggcauc aaggucaccu acauggagga ggagcgcaac uucaccaccg      420

agcaggucac cgccaugcuc cucuccaagc ucaaggagac cgccgagucc guccucaaga      480

agcccgucgu cgacugcguc gucuccgucc ccugcuucua caccgacgcc gagcgccgcu      540

ccgucaugga cgccacccag aucgccggcc ucaacugccu ccgccucaug aacgagacca      600

ccgccgucgc ccucgccuac ggcaucuaca agcaggaccu ccccgcccuc gaggagaagc      660

cccgcaacgu cgucuucguc gacaugggcc acuccgccua ccaggucucc gucugcgccu      720

ucaaccgcgg caagcucaag guccucgcca ccgccuucga caccacccuc ggcggccgca      780

aguucgacga gguccucguc aaccacuucu gcgaggaguu cggcaagaag uacaagcucg      840

acaucaaguc caagauccgc gcccuccucc gccucuccca ggagugcgag aagcucaaga      900

agcucauguc cgccaacgcc uccgaccucc cccucuccau cgagugcuuc augaacgacg      960

ucgacgucuc cggcaccaug aaccgcggca aguuccucga gaugugcaac gaccuccucg     1020

cccgcgucga gcccccccuc cgcuccgucc ucgagcagac caagcucaag aaggaggaca     1080

ucuacgccgu cgagaucguc ggcggcgcca cccgcauccc cgccgucaag gagaagaucu     1140

ccaaguucuu cggcaaggag cucuccacca cccucaacgc cgacgaggcc gucacccgcg     1200

gcugcgcccu ccagugcgcc auccucuccc ccgccuucaa gguccgcgag uucuccauca     1260

ccgacgucgu ccccuacccc aucucccucc gcuggaacuc ccccgccgag gagggcuccu     1320

ccgacugcga ggucuucucc aagaaccacg ccgcccccuu cuccaagguc cucaccuucu     1380

accgcaagga gcccuucacc cucgaggccu acuacuccuc cccccaggac cuccccuacc     1440

ccgaccccgc caucgcccag uucuccgucc agaaggucac cccccagucc gacggcuccu     1500

ccuccaaggu caaggucaag guccgcguca acguccacgg caucuucucc gucuccuccg     1560

ccucccucgu cgagguccac aaguccgagg agaacgagga gcccauggag accgaccaga     1620

acgccaagga ggaggagaag augcaggucg accaggagga gccccacguc gaggagcagc     1680

agcagcagac ccccgccgag aacaaggccg aguccgagga gauggagacc ucccaggccg     1740

gcuccaagga caagaagaug gaccagcccc cccaggccaa gaaggccaag gucaagaccu     1800

ccaccgucga ccuccccauc gagaaccagc uccucuggca gaucgaccgc gagaugcuca     1860

accucuacau cgagaacgag ggcaagauga ucaugcagga caagcucgag aaggagcgca     1920

acgacgccaa gaacgccguc gaggaguacg ucuacgagau gcgcgacaag cucuccggcg     1980

aguacgagaa guucgucucc gaggacgacc gcaacuccuu cacccucaag cucgaggaca     2040

ccgagaacug gcucuacgag gacggcgagg accagcccaa gcaggucuac gucgacaagc     2100

ucgccgagcu caagaaccuc ggccagccca ucaagauccg cuuccaggag uccgaggagc     2160

gccccaagcu cuucgaggag cucggcaagc agauccagca guacaugaag aucaucuccu     2220

ccuucaagaa caaggaggac caguacgacc accucgacgc cgccgacaug accaaggucg     2280

agaaguccac caacgaggcc auggagugga ugaacaacaa gcucaaccuc cagaacaagc     2340

agucccucac cauggacccc gucgucaagu ccaaggagau cgaggccaag aucaaggagc     2400

ucaccuccac cugcuccccc aucaucucca agcccaagcc caaggucgag ccccccaagg     2460

aggagcagaa gaacgccgag cagaacggcc ccgucgacgg ccagggcgac aaccccggcc     2520

cccaggccgc cgagcagggc accgacaccg ccguccccuc cgacuccgac aagaagcucc     2580

ccgagaugga caucgacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  6462
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt2)

<400>  6462
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgucgucg gcaucgaccu cggcuuccuc aacugcuaca      120

ucgccgucgc ccgcuccggc ggcaucgaga ccaucgccaa cgaguacucc gaccgcugca      180

cccccgccug caucucccuc ggcucccgca cccgcgccau cggcaacgcc gccaaguccc      240

agaucgucac caacguccgc aacaccaucc acggcuucaa gaagcuccac ggccgcuccu      300

ucgacgaccc caucguccag accgagcgca uccgccuccc cuacgagcuc cagaagaugc      360

ccaacggcuc cgccggcguc aagguccgcu accucgagga ggagcgcccc uucgccaucg      420

agcaggucac cggcaugcuc cucgccaagc ucaaggagac cuccgagaac gcccucaaga      480

agcccgucgc cgacugcguc aucuccaucc ccuccuucuu caccgacgcc gagcgccgcu      540

ccgucauggc cgccgcccag gucgccggcc ucaacugccu ccgccucaug aacgagacca      600

ccgccgucgc ccucgccuac ggcaucuaca agcaggaccu ccccccccuc gacgagaagc      660

cccgcaacgu cgucuucauc gacaugggcc acuccgccua ccagguccuc gucugcgccu      720

ucaacaaggg caagcucaag guccucgcca ccaccuucga ccccuaccuc ggcggccgca      780

acuucgacga ggcccucguc gacuacuucu gcgacgaguu caagaccaag uacaagauca      840

acgucaagga gaacucccgc gcccuccucc gccucuacca ggagugcgag aagcucaaga      900

agcucauguc cgccaacgcc uccgaccucc cccucaacau cgagugcuuc augaacgacc      960

ucgacgucuc cuccaagaug aaccgcgccc aguucgagca gcucugcgcc ucccuccucg     1020

cccgcgucga gcccccccuc aaggccguca uggagcaggc caaccuccag cgcgaggaca     1080

ucuccuccau cgagaucguc ggcggcgcca cccgcauccc cgccgucaag gagcagauca     1140

ccaaguucuu ccucaaggac aucuccacca cccucaacgc cgacgaggcc gucgcccgcg     1200

gcugcgcccu ccagugcgcc auccucuccc ccgccuucaa gguccgcgag uucuccauca     1260

ccgaccucgu ccccuacucc aucacccucc gcuggaagac cuccuucgag gacggcuccg     1320

gcgagugcga ggucuucugc aagaaccacc ccgcccccuu cuccaagguc aucaccuucc     1380

acaagaagga gcccuucgag cucgaggccu ucuacaccaa ccuccacgag guccccuacc     1440

ccgacgcccg caucggcucc uucaccaucc agaacgucuu cccccagucc gacggcgacu     1500

ccuccaaggu caaggucaag guccgcguca acauccacgg caucuucucc gucgccuccg     1560

ccuccgucau cgagaagcag aaccucgagg gcgaccacuc cgacgccccc auggagaccg     1620

agaccuccuu caagaacgag aacaaggaca acauggacaa gaugcagguc gaccaggagg     1680

agggccacca gaagugccac gccgagcaca cccccgagga ggagaucgac cacaccggcg     1740

ccaagaccaa guccgccguc uccgacaagc aggaccgccu caaccagacc cucaagaagg     1800

gcaaggucaa guccaucgac cuccccaucc aguccucccu cugccgccag cucggccagg     1860

accuccucaa cuccuacauc gagaacgagg gcaagaugau caugcaggac aagcucgaga     1920

aggagcgcaa cgacgccaag aacgccgucg aggaguacgu cuacgacuuc cgcgaccgcc     1980

ucggcaccgu cuacgagaag uucaucaccc ccgaggaccu cuccaagcuc uccgccgucc     2040

ucgaggacac cgagaacugg cucuacgagg acggcgagga ccagcccaag caggucuacg     2100

ucgacaagcu ccaggagcuc aagaaguacg gccagcccau ccagaugaag uacauggagc     2160

acgaggagcg ccccaaggcc cucaacgacc ucggcaagaa gauccagcuc gucaugaagg     2220

ucaucgaggc cuaccgcaac aaggacgagc gcuacgacca ccucgacccc accgagaugg     2280

agaaggucga gaagugcauc uccgacgcca uguccuggcu caacuccaag augaacgccc     2340

agaacaagcu cucccucacc caggaccccg ucgucaaggu cuccgagauc gucgccaagu     2400

ccaaggagcu cgacaacuuc ugcaacccca ucaucuacaa gcccaagccc aaggccgagg     2460

uccccgagga caagcccaag gccaacuccg agcacaacgg ccccauggac ggccaguccg     2520

gcaccgagac caaguccgac uccaccaagg acuccuccca gcacaccaag uccuccggcg     2580

agauggaggu cgacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  6463
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt2)

<400>  6463
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcucuccc ucgucgccgc caugcuccuc cuccucuccg      120

ccgcccgcgc cgaggaggag gacaagaagg aggacgucgg caccgucguc ggcaucgacc      180

ucggcaccac cuacuccugc gucggcgucu ucaagaacgg ccgcgucgag aucaucgcca      240

acgaccaggg caaccgcauc acccccuccu acgucgccuu cacccccgag ggcgagcgcc      300

ucaucggcga cgccgccaag aaccagcuca ccuccaaccc cgagaacacc gucuucgacg      360

ccaagcgccu caucggccgc accuggaacg accccuccgu ccagcaggac aucaaguucc      420

uccccuucaa ggucgucgag aagaagacca agcccuacau ccaggucgac aucggcggcg      480

gccagaccaa gaccuucgcc cccgaggaga ucuccgccau gguccucacc aagaugaagg      540

agaccgccga ggccuaccuc ggcaagaagg ucacccacgc cgucgucacc guccccgccu      600

acuucaacga cgcccagcgc caggccacca aggacgccgg caccaucgcc ggccucaacg      660

ucaugcgcau caucaacgag cccaccgccg ccgccaucgc cuacggccuc gacaagcgcg      720

agggcgagaa gaacauccuc gucuucgacc ucggcggcgg caccuucgac gucucccucc      780

ucaccaucga caacggcguc uucgaggucg ucgccaccaa cggcgacacc caccucggcg      840

gcgaggacuu cgaccagcgc gucauggagc acuucaucaa gcucuacaag aagaagaccg      900

gcaaggacgu ccgcaaggac aaccgcgccg uccagaagcu ccgccgcgag gucgagaagg      960

ccaagcgcgc ccucuccucc cagcaccagg cccgcaucga gaucgagucc uucuacgagg     1020

gcgaggacuu cuccgagacc cucacccgcg ccaaguucga ggagcucaac auggaccucu     1080

uccgcuccac caugaagccc guccagaagg uccucgagga cuccgaccuc aagaaguccg     1140

acaucgacga gaucguccuc gucggcggcu ccacccgcau ccccaagauc cagcagcucg     1200

ucaaggaguu cuucaacggc aaggagcccu cccgcggcau caaccccgac gaggccgucg     1260

ccuacggcgc cgccguccag gccggcgucc ucuccggcga ccaggacacc ggcgaccucg     1320

uccuccucga cgucugcccc cucacccucg gcaucgagac cgucggcggc gucaugacca     1380

agcucauccc ccgcaacacc gucgucccca ccaagaaguc ccagaucuuc uccaccgccu     1440

ccgacaacca gcccaccguc accaucaagg ucuacgaggg cgagcgcccc cucaccaagg     1500

acaaccaccu ccucggcacc uucgaccuca ccggcauccc ccccgccccc cgcggcgucc     1560

cccagaucga ggucaccuuc gagaucgacg ucaacggcau ccuccgcguc accgccgagg     1620

acaagggcac cggcaacaag aacaagauca ccaucaccaa cgaccagaac cgccucaccc     1680

ccgaggagau cgagcgcaug gucaacgacg ccgagaaguu cgccgaggag gacaagaagc     1740

ucaaggagcg caucgacacc cgcaacgagc ucgaguccua cgccuacucc cucaagaacc     1800

agaucggcga caaggagaag cucggcggca agcucuccuc cgaggacaag gagaccaugg     1860

agaaggccgu cgaggagaag aucgaguggc ucgaguccca ccaggacgcc gacaucgagg     1920

acuucaaggc caagaagaag gagcucgagg agaucgucca gcccaucauc uccaagcucu     1980

acggcuccgc cggccccccc cccaccggcg aggaggacac cgccgagaag gacgagcucu     2040

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  6464
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt2)

<400>  6464
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggcccccc gcgagcucgc cgucggcauc gaccucggca      120

ccaccuacuc cugcgucggc gucuuccagc agggccgcgu cgagauccuc gccaacgacc      180

agggcaaccg caccaccccc uccuacgucg ccuucaccga caccgagcgc cucgucggcg      240

acgccgccaa gucccaggcc gcccucaacc cccacaacac cgucuucgac gccaagcgcc      300

ucaucggccg caaguucgcc gacaccaccg uccaguccga caugaagcac uggcccuucc      360

gcgucgucuc cgagggcggc aagcccaagg uccgcgucug cuaccgcggc gaggacaaga      420

ccuucuaccc cgaggagauc uccuccaugg uccucuccaa gaugaaggag accgccgagg      480

ccuaccucgg ccagcccguc aagcacgccg ucaucaccgu ccccgccuac uucaacgacu      540

cccagcgcca ggccaccaag gacgccggcg ccaucgccgg ccucaacguc cuccgcauca      600

ucaacgagcc caccgccgcc gccaucgccu acggccucga ccgccgcggc gccggcgagc      660

gcaacguccu caucuucgac cucggcggcg gcaccuucga cgucuccguc cucuccaucg      720

acgccggcgu cuucgagguc aaggccaccg ccggcgacac ccaccucggc ggcgaggacu      780

ucgacaaccg ccucgucaac cacuucaugg aggaguuccg ccgcaagcac ggcaaggacc      840

ucuccggcaa caagcgcgcc cuccgccgcc uccgcaccgc cugcgagcgc gccaagcgca      900

cccucuccuc cuccacccag gccacccucg agaucgacuc ccucuucgag ggcgucgacu      960

ucuacaccuc caucacccgc gcccgcuucg aggagcucug cuccgaccuc uuccgcucca     1020

cccucgagcc cgucgagaag gcccuccgcg acgccaagcu cgacaaggcc cagauccacg     1080

acgucguccu cgucggcggc uccacccgca uccccaaggu ccagaagcuc cuccaggacu     1140

ucuucaacgg caaggagcuc aacaagucca ucaaccccga cgaggccguc gccuacggcg     1200

ccgccgucca ggccgccguc cucaugggcg acaagugcga gaagguccag gaccuccucc     1260

uccucgacgu cgccccccuc ucccucggcc ucgagaccgc cggcggcguc augaccaccc     1320

ucauccagcg caacgccacc auccccacca agcagaccca gaccuucacc accuacuccg     1380

acaaccagcc cggcgucuuc auccaggucu acgagggcga gcgcgccaug accaaggaca     1440

acaaccuccu cggccgcuuc gagcucuccg gcaucccccc cgccccccgc ggcguccccc     1500

agaucgaggu caccuucgac aucgacgcca acggcauccu cuccgucacc gccaccgacc     1560

gcuccaccgg caaggccaac aagaucacca ucaccaacga caagggccgc cucuccaagg     1620

aggaggucga gcgcaugguc cacgaggccg agcaguacaa ggccgaggac gaggcccagc     1680

gcgaccgcgu cgccgccaag aacucccucg aggcccacgu cuuccacguc aagggcuccc     1740

uccaggagga gucccuccgc gacaagaucc ccgaggagga ccgccgcaag augcaggaca     1800

agugccgcga gguccucgcc uggcucgagc acaaccagcu cgccgagaag gaggaguacg     1860

agcaccagaa gcgcgagcuc gagcagaucu gccgccccau cuucucccgc cucuacggcg     1920

gccccggcgu ccccggcggc uccuccugcg gcacccaggc ccgccagggc gaccccucca     1980

ccggccccau caucgaggag gucgacugag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  6465
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt2)

<400>  6465
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggcccccc gcgagcucgc cgucggcauc gaccucggca      120

ccaccuacuc cugcgucggc gucuuccagc agggccgcgu cgagauccuc gccaacgacc      180

agggcaaccg caccaccccc uccuacgucg ccuucaccga caccgagcgc cucgucggcg      240

acgccgccaa gucccaggcc gcccucaacc cccacaacac cgucuucgac gccaagcgcc      300

ucaucggccg caaguucgcc gacaccaccg uccaguccga caugaagcac uggcccuucc      360

aggucgucuc cgagggcggc aagcccaagg uccgcgucug cuaccgcggc gaggacaaga      420

ccuucuaccc cgaggagauc uccuccaugg uccucuccaa gaugaaggag accgccgagg      480

ccuaccucgg ccagcccguc aagcacgccg ucaucaccgu ccccaccuac uucuccaacu      540

cccagcgcca ggccaccaag gacgccggcg ccaucgccgg ccucaagguc cuccccauca      600

ucaacgaggc caccgccgcc gccaucgccu acggccucga ccgccgcggc gccggcaagc      660

gcaacguccu caucuucgac cucggcggcg gcaccuucga cgucuccguc cucuccaucg      720

acgccggcgu cuucgagguc aaggccaccg ccggcgacac ccaccucggc ggcgaggacu      780

ucgacaaccg ccucgucaac cacuucaugg aggaguuccg ccgcaagcac ggcaaggacc      840

ucuccggcaa caagcgcgcc cuccgccgcc uccgcaccgc cugcgagcgc gccaagcgca      900

cccccuccuc cuccacccag gccacccucg agaucgacuc ccucuucgag ggcgucgacu      960

ucuacaaguc caucacccgc gcccgcuucg aggagcucug cuccgaccuc uuccgcucca     1020

cccucgagcc cgucgagaag gcccuccgcg acgccaagcu cgacaaggcc cagauccacg     1080

acuucguccu cggcggcggc cuccacuccc acccccaggg cgccgagguc gccgccggcc     1140

uccuccagcg ccagggcgcc gagcaggagc accagcccug aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  6466
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt2)

<400>  6466
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccaagggcc ccgccgucgg caucgaccuc ggcaccaccu      120

acuccugcgu cggcgucuuc cagcacggca aggucgagau caucgccaac gaccagggca      180

accgcaccac ccccuccuac gucgccuuca ccgacaccga gcgccucauc ggcgacgccg      240

ccaagaacca ggucgccaug aaccccacca acaccgucuu cgacgccaag cgccucaucg      300

gccgccgcuu cgacgacgcc gucguccagu ccgacaugaa gcacuggccc uucauggucg      360

ucaacgacgc cggccgcccc aagguccagg ucgaguacaa gggcgagacc aaguccuucu      420

accccgagga ggucuccucc augguccuca ccaagaugaa ggagaucgcc gaggccuacc      480

ucggcaagac cgucaccaac gccgucguca ccguccccgc cuacuucaac gacucccagc      540

gccaggccac caaggacgcc ggcaccaucg ccggccucaa cguccuccgc aucaucaacg      600

agcccaccgc cgccgccauc gccuacggcc ucgacaagaa ggucggcgcc gagcgcaacg      660

uccucaucuu cgaccucggc ggcggcaccu ucgacgucuc cauccucacc aucgaggacg      720

gcaucuucga ggucaagucc accgccggcg acacccaccu cggcggcgag gacuucgaca      780

accgcauggu caaccacuuc aucgccgagu ucaagcgcaa gcacaagaag gacaucuccg      840

agaacaagcg cgccguccgc cgccuccgca ccgccugcga gcgcgccaag cgcacccucu      900

ccuccuccac ccaggccucc aucgagaucg acucccucua cgagggcauc gacuucuaca      960

ccuccaucac ccgcgcccgc uucgaggagc ucaacgccga ccucuuccgc ggcacccucg     1020

accccgucga gaaggcccuc cgcgacgcca agcucgacaa gucccagauc cacgacaucg     1080

uccucgucgg cggcuccacc cgcaucccca agauccagaa gcuccuccag gacuucuuca     1140

acggcaagga gcucaacaag uccaucaacc ccgacgaggc cgucgccuac ggcgccgccg     1200

uccaggccgc cauccucucc ggcgacaagu ccgagaacgu ccaggaccuc cuccuccucg     1260

acgucacccc ccucucccuc ggcaucgaga ccgccggcgg cgucaugacc guccucauca     1320

agcgcaacac caccaucccc accaagcaga cccagaccuu caccaccuac uccgacaacc     1380

agcccggcgu ccucauccag gucuacgagg gcgagcgcgc caugaccaag gacaacaacc     1440

uccucggcaa guucgagcuc accggcaucc cccccgcccc ccgcggcguc ccccagaucg     1500

aggucaccuu cgacaucgac gccaacggca uccucaacgu cuccgccguc gacaagucca     1560

ccggcaagga gaacaagauc accaucacca acgacaaggg ccgccucucc aaggaggaca     1620

ucgagcgcau gguccaggag gccgagaagu acaaggccga ggacgagaag cagcgcgaca     1680

aggucuccuc caagaacucc cucgaguccu acgccuucaa caugaaggcc accgucgagg     1740

acgagaagcu ccagggcaag aucaacgacg aggacaagca gaagauccuc gacaagugca     1800

acgagaucau caacuggcuc gacaagaacc agaccgccga gaaggaggag uucgagcacc     1860

agcagaagga gcucgagaag gucugcaacc ccaucaucac caagcucuac caguccgccg     1920

gcggcaugcc cggcggcaug cccggcggcu uccccggcgg cggcgccccc cccuccggcg     1980

gcgccuccuc cggccccacc aucgaggagg ucgacugagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  6467
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt2)

<400>  6467
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucuccgccu cccgcgccgc cgccgcccgc cucgucggcg      120

ccgccgccuc ccgcggcccc accgccgccc gccaccagga cuccuggaac ggccucuccc      180

acgaggccuu ccgccucguc ucccgccgcg acuacgccuc cgaggccauc aagggcgccg      240

ucgucggcau cgaccucggc accaccaacu ccugcgucgc cgucauggag ggcaagcagg      300

ccaagguccu cgagaacgcc gagggcgccc gcaccacccc cuccgucguc gccuucaccg      360

ccgacggcga gcgccucguc ggcaugcccg ccaagcgcca ggccgucacc aaccccaaca      420

acaccuucua cgccaccaag cgccucaucg gccgccgcua cgacgacccc gagguccaga      480

aggacaucaa gaacgucccc uucaagaucg uccgcgccuc caacggcgac gccugggucg      540

aggcccacgg caagcucuac ucccccuccc agaucggcgc cuucguccuc augaagauga      600

aggagaccgc cgagaacuac cucggccaca ccgccaagaa cgccgucauc accguccccg      660

ccuacuucaa cgacucccag cgccaggcca ccaaggacgc cggccagauc uccggccuca      720

acguccuccg cgucaucaac gagcccaccg ccgccgcccu cgccuacggc cucgacaagu      780

ccgaggacaa ggucaucgcc gucuacgacc ucggcggcgg caccuucgac aucuccaucc      840

ucgagaucca gaagggcguc uucgagguca aguccaccaa cggcgacacc uuccucggcg      900

gcgaggacuu cgaccaggcc cuccuccgcc acaucgucaa ggaguucaag cgcgagaccg      960

gcgucgaccu caccaaggac aacauggccc uccagcgcgu ccgcgaggcc gccgagaagg     1020

ccaagugcga gcucuccucc uccguccaga ccgacaucaa ccuccccuac cucaccaugg     1080

acuccuccgg ccccaagcac cucaacauga agcucacccg cgcccaguuc gagggcaucg     1140

ucaccgaccu cauccgccgc accaucgccc ccugccagaa ggccaugcag gacgccgagg     1200

ucuccaaguc cgacaucggc gaggucaucc ucgucggcgg caugacccgc augcccaagg     1260

uccagcagac cguccaggac cucuucggcc gcgcccccuc caaggccguc aaccccgacg     1320

aggccgucgc caucggcgcc gccauccagg gcggcguccu cgccggcgac gucaccgacg     1380

uccuccuccu cgacgucacc ccccucuccc ucggcaucga gacccucggc ggcgucuuca     1440

ccaagcucau caaccgcaac accaccaucc ccaccaagaa gucccagguc uucuccaccg     1500

ccgccgacgg ccagacccag gucgagauca aggucugcca gggcgagcgc gagauggccg     1560

gcgacaacaa gcuccucggc caguucaccc ucaucggcau cccccccgcc ccccgcggcg     1620

ucccccagau cgaggucacc uucgacaucg acgccaacgg caucguccac gucuccgcca     1680

aggacaaggg caccggccgc gagcagcaga ucgucaucca guccuccggc ggccucucca     1740

aggacgacau cgagaacaug gucaagaacg ccgagaagua cgccgaggag gaccgccgca     1800

agaaggagcg cgucgaggcc gucaacaugg ccgagggcau cauccacgac accgagacca     1860

agauggagga guucaaggac cagcuccccg ccgacgagug caacaagcuc aaggaggaga     1920

ucuccaagau gcgcgagcuc cucgcccgca aggacuccga gaccggcgag aacauccgcc     1980

aggccgccuc cucccuccag caggccuccc ucaagcucuu cgagauggcc uacaagaaga     2040

uggccuccga gcgcgagggc uccggcuccu ccggcaccgg cgagcagaag gaggaccaga     2100

aggaggagaa gcagugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  6468
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt2)

<400>  6468
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg aggccggcgg cuccgacggc ccccgcgaga      120

ccgcccccac cuccgccuac uccucccccg cccgcucccu cggcgacacc ggcaucaccc      180

cccucucccc cucccacauc gucaacgaca ccgacuccaa cgucuccgag cagcaguccu      240

uccucgucgu cgucgccguc gacuucggca ccaccuccuc cggcuacgcc uacuccuuca      300

ccaaggagcc cgagugcauc cacgucaugc gccgcuggga gggcggcgac cccggcgucu      360

ccaaccagaa gacccccacc accauccucc ucacccccga gcgcaaguuc cacuccuucg      420

gcuacgccgc ccgcgacuuc uaccacgacc ucgaccccaa cgaggccaag caguggcucu      480

accucgagaa guucaagaug aagcuccaca ccaccggcga ccucaccaug gacaccgacc      540

ucaccgccgc caacggcaag aaggucaagg cccucgagau cuucgccuac gcccuccagu      600

acuucaagga gcaggcccuc aaggagcucu ccgaccaggc cggcuccgag uucgagaacu      660

ccgacguccg cugggucauc accguccccg ccaucuggaa gcagcccgcc aagcaguuca      720

ugcgccaggc cgccuaccag gccggccucg ccucccccga gaacuccgag cagcucauca      780

ucgcccucga gcccgaggcc gccuccaucu acugccgcaa gcuccgccuc caccagauga      840

ucgagcucuc cuccaaggcc gccgucaacg gcuacuccgg cuccgacacc gucggcgccg      900

gcuucaccca ggccaaggag cacauccgcc gcaaccgcca gucccgcacc uuccucgucg      960

agaacgucau cggcgagauc ugguccgagc ucgaggaggg cgacaaguac gucgucgucg     1020

acuccggcgg cggcaccguc gaccucaccg uccaccagau ccgccucccc gagggccacc     1080

ucaaggagcu cuacaaggcc accggcggcc ccuacggcuc ccucggcguc gacuacgagu     1140

ucgagaagcu ccucuacaag aucuucggcg aggacuucau cgagcaguuc aagaucaagc     1200

gccccgccgc cugggucgac cucaugaucg ccuucgaguc ccgcaagcgc gccgccgccc     1260

ccgaccgcac caacccccuc aacaucaccc uccccuucuc cuucaucgac uacuacaaga     1320

aguuccgcgg ccacuccguc gagcacgccc uccgcaaguc caacgucgac uucgucaagu     1380

gguccuccca gggcaugcuc cgcauguccc ccgacgccau gaacgcccuc uucaagccca     1440

ccaucgacuc caucaucgag caccuccgcg accucuucca gaagcccgag gucuccaccg     1500

ucaaguuccu cuuccucguc ggcggcuucg ccgaggcccc ccuccuccag caggccgucc     1560

aggccgccuu cggcgaccag ugccgcauca ucauccccca ggacgucggc cucaccaucc     1620

ucaagggcgc cguccucuuc ggccucgacc ccgccgucau caagguccgc cgcucccccc     1680

ucaccuacgg cgucggcguc cucaaccgcu acgucgaggg caagcacccc cccgagaagc     1740

uccucgucaa ggacggcacc cgcuggugca ccgacgucuu cgacaaguuc aucuccgccg     1800

accaguccgu cgcccucggc gagcucguca agcgcuccua cacccccgcc aagcccuccc     1860

agcucgucau cgucaucaac aucuacuccu ccgagcacga caacgucucc uucaucaccg     1920

accccggcgu caagaagugc ggcacccucc gccucgaccu caccggcacc uccggcaccg     1980

ccguccccgc ccgccgcgag auccagaccc ucaugcaguu cggcgacacc gagaucaagg     2040

ccaccgccau cgacaucgcc accuccaagu ccgucaaggu cggcaucgac uuccucaacu     2100

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  6469
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt2)

<400>  6469
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cucgccgucc ccgagauggg ccuccagggc cucuacaucg      120

gcuccucccc cgagcgcucc cccguccccu ccccccccgg cuccccccgc acccaggagu      180

ccugcggcau cgccccccuc acccccuccc agucccccaa gcccgagguc cgcgcccccc      240

agcaggccuc cuucuccguc gucgucgcca ucgacuucgg caccaccucc uccggcuacg      300

ccuucuccuu cgccuccgac cccgaggcca uccacaugau gcgcaagugg gagggcggcg      360

accccggcgu cgcccaccag aagaccccca ccugccuccu ccucaccccc gagggcgccu      420

uccacuccuu cggcuacacc gcccgcgacu acuaccacga ccucgacccc gaggaggccc      480

gcgacuggcu cuacuucgag aaguucaaga ugaagaucca cuccgccacc gaccucaccc      540

ucaagaccca gcucgaggcc gucaacggca agaccaugcc cgcccucgag gucuucgccc      600

acgcccuccg cuucuuccgc gagcacgccc uccaggagcu ccgcgagcag ucccccuccc      660

uccccgagaa ggacaccguc cgcugggucc ucaccguccc cgccaucugg aagcagcccg      720

ccaagcaguu caugcgcgag gccgccuacc ucgccggccu cgucucccgc gagaacgccg      780

agcagcuccu caucgcccuc gagcccgagg ccgccuccgu cuacugccgc aagcuccgcc      840

uccaccagcu ccucgaccuc uccggccgcg cccccggcgg cggccgccuc ggcgagcgcc      900

gcuccaucga cuccuccuuc cgccaggccc gcgagcagcu ccgccgcucc cgccacuccc      960

gcaccuuccu cgucgagucc ggcgucggcg agcucugggc cgagaugcag gccggcgacc     1020

gcuacgucgu cgccgacugc ggcggcggca ccgucgaccu caccguccac cagcucgagc     1080

agccccacgg cacccucaag gagcucuaca aggccuccgg cggccccuac ggcgccgucg     1140

gcgucgaccu cgccuucgag cagcuccucu gccgcaucuu cggcgaggac uucaucgcca     1200

ccuucaagcg ccagcgcccc gccgccuggg ucgaccucac caucgccuuc gaggcccgca     1260

agcgcaccgc cggcccccac cgcgccggcg cccucaacau cucccucccc uucuccuuca     1320

ucgacuucua ccgcaagcag cgcggccaca acgucgagac cgcccuccgc cgcuccuccg     1380

ucaacuucgu caaguggucc ucccagggca ugcuccgcau guccugcgag gccaugaacg     1440

agcucuucca gcccaccguc uccggcauca uccagcacau cgaggcccuc cucgcccgcc     1500

ccgaggucca gggcgucaag cuccucuucc ucgucggcgg cuucgccgag uccgccgucc     1560

uccagcacgc cguccaggcc gcccucggcg cccgcggccu ccgcgucguc gucccccacg     1620

acgucggccu caccauccuc aagggcgccg uccucuucgg ccaggccccc ggcgucgucc     1680

gcguccgccg cuccccccuc accuacggcg ucggcguccu caaccgcuuc guccccggcc     1740

gccacccccc cgagaagcuc cucguccgcg acggccgccg cuggugcacc gacgucuucg     1800

agcgcuucgu cgccgccgag caguccgucg cccucggcga ggagguccgc cgcuccuacu     1860

gccccgcccg ccccggccag cgccgcgucc ucaucaaccu cuacugcugc gccgccgagg     1920

acgcccgcuu caucaccgac cccggcgucc gcaagugcgg cgcccucucc cucgagcucg     1980

agcccgccga cugcggccag gacaccgccg gcgccccccc cggccgccgc gagauccgcg     2040

ccgccaugca guucggcgac accgagauca aggucaccgc cgucgacguc uccaccaacc     2100

gcuccguccg cgccuccauc gacuuccucu ccaacugagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  6470
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt2)

<400>  6470
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgcgaga ugaccauccu cggcuccgcc guccucaccc      120

uccuccucgc cggcuaccuc gcccagcagu accucccccu ccccaccccc aaggucaucg      180

gcaucgaccu cggcaccacc uacugcuccg ucggcgucuu cuuccccggc accggcaagg      240

ucaaggucau ccccgacgag aacggccaca ucuccauccc cuccaugguc uccuucaccg      300

acaacgacgu cuacgucggc uacgaguccg ucgagcucgc cgacuccaac ccccagaaca      360

ccaucuacga cgccaagcgc uucaucggca agaucuucac cgccgaggag cucgaggccg      420

agaucggccg cuaccccuuc aagguccuca acaagaacgg cauggucgag uucuccguca      480

ccuccaacga gaccaucacc gucucccccg aguacgucgg cucccgccuc cuccucaagc      540

ucaaggagau ggccgaggcc uaccucggca ugcccgucgc caacgccguc aucuccgucc      600

ccgccgaguu cgaccucaag cagcgcaacu ccaccaucga ggccgccaac cucgccggcc      660

ucaagauccu ccgcgucauc aacgagccca ccgccgccgc cauggccuac ggccuccaca      720

aggccgacgu cuuccacguc cucgucaucg accucggcgg cggcacccuc gacgucuccc      780

uccucaacaa gcagggcggc auguuccuca cccgcgccau guccggcaac aacaagcucg      840

gcggccagga cuucaaccag cgccuccucc aguaccucua caagcagauc uaccagaccu      900

acggcuucgu ccccucccgc aaggaggaga uccaccgccu ccgccaggcc gucgagaugg      960

ucaagcucaa ccucacccuc caccaguccg cccagcucuc cguccuccuc accgucgagg     1020

agcaggaccg caaggagccc cacuccuccg acaccgagcu ccccaaggac aagcucuccu     1080

ccgccgacga ccaccgcguc aacuccggcu ucggccgcgg ccucuccgac aagaaguccg     1140

gcgaguccca gguccucuuc gagaccgaga ucucccgcaa gcucuucgac acccucaacg     1200

aggaccucuu ccagaagauc cucgucccca uccagcaggu ccucaaggag ggccaccucg     1260

agaagaccga gaucgacgag gucguccucg ucggcggcuc cacccgcauc ccccgcaucc     1320

gccaggucau ccaggaguuc uucggcaagg accccaacac cuccgucgac cccgaccucg     1380

ccgucgucac cggcgucgcc auccaggccg gcaucgacgg cggcuccugg ccccuccagg     1440

ucuccgcccu cgagaucccc aacaagcacc uccagaagac caacuucaac ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6471
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt2)

<400>  6471
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgccaucg gcguccaccu cggcugcacc uccgccugcg      120

ucgccgucua caaggacggc cgcgccggcg ucgucgccaa cgacgccggc gaccgcguca      180

cccccgccgu cgucgccuac uccgagaacg aggagaucgu cggccucgcc gccaagcagu      240

cccgcauccg caacaucucc aacaccguca ugaaggucaa gcagauccuc ggccgcuccu      300

ccuccgaccc ccaggcccag aaguacaucg ccgaguccaa gugccucguc aucgagaaga      360

acggcaagcu ccgcuacgag aucgacaccg gcgaggagac caaguucguc aaccccgagg      420

acgucgcccg ccucaucuuc uccaagauga aggagaccgc ccacuccguc cucggcuccg      480

acgccaacga cgucgucauc accguccccu ucgacuucgg cgagaagcag aagaacgccc      540

ucggcgaggc cgcccgcgcc gccggcuuca acguccuccg ccucauccac gagcccuccg      600

ccgcccuccu cgccuacggc aucggccagg acucccccac cggcaagucc aacauccucg      660

ucuucaagcu cggcggcacc ucccucuccc ucuccgucau ggaggucaac uccggcaucu      720

accgcguccu cuccaccaac accgacgaca acaucggcgg cgcccacuuc accgagaccc      780

ucgcccagua ccucgccucc gaguuccagc gcuccuucaa gcacgacguc cgcggcaacg      840

cccgcgccau gaugaagcuc accaacuccg ccgaggucgc caagcacucc cucuccaccc      900

ucggcuccgc caacugcuuc cucgacuccc ucuacgaggg ccaggacuuc gacugcaacg      960

ucucccgcgc ccgcuucgag cuccucugcu ccccccucuu caacaagugc aucgaggcca     1020

uccgcggccu ccucgaccag aacggcuuca ccgccgacga caucaacaag gucguccucu     1080

gcggcggcuc cucccgcauc cccaagcucc agcagcucau caaggaccuc uuccccgccg     1140

ucgagcuccu caacuccauc ccccccgacg aggucauccc caucggcgcc gccaucgagg     1200

ccggcauccu caucggcaag gagaaccucc ucgucgagga cucccucaug aucgagugcu     1260

ccgcccgcga cauccucguc aagggcgucg acgaguccgg cgccucccgc uucaccgucc     1320

ucuuccccuc cggcaccccc cuccccgccc gccgccagca cacccuccag gcccccggcu     1380

ccaucuccuc cgucugccuc gagcucuacg aguccgacgg caagaacucc gccaaggagg     1440

agaccaaguu cgcccagguc guccuccagg accucgacaa gaaggagaac ggccuccgcg     1500

acauccucgc cguccucacc augaagcgcg acggcucccu ccacgucacc ugcaccgacc     1560

aggagaccgg caagugcgag gccaucucca ucgagaucgc cuccugagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  6472
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt2)

<400>  6472
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgucgucg gccucgacgu cggcucccag uccugcuaca      120

ucgccgucgc ccgcgccggc ggcaucgaga ccaucgccaa cgaguucucc gaccgcugca      180

cccccuccgu caucuccuuc ggcuccaaga accgcaccau cggcgucgcc gccaagaacc      240

agcagaucac ccacgccaac aacaccgucu ccaacuucaa gcgcuuccac ggccgcgccu      300

ucaacgaccc cuucauccag aaggagaagg agaaccucuc cuacgaccuc gucccccuca      360

agaacggcgg cgucggcauc aaggucaugu acaugggcga ggagcaccuc uucuccgucg      420

agcagaucac cgccaugcuc cucaccaagc ucaaggagac cgccgagaac ucccucaaga      480

agcccgucac cgacugcguc aucuccgucc ccuccuucuu caccgacgcc gagcgccgcu      540

ccguccucga cgccgcccag aucgucggcc ucaacugccu ccgccucaug aacgacauga      600

ccgccgucgc ccucaacuac ggcaucuaca agcaggaccu ccccucccuc gacgagaagc      660

cccgcaucgu cgucuucguc gacaugggcc acuccgccuu ccaggucucc gccugcgccu      720

ucaacaaggg caagcucaag guccucggca ccgccuucga ccccuuccuc ggcggcaaga      780

acuucgacga gaagcucguc gagcacuucu gcgccgaguu caagaccaag uacaagcucg      840

acgccaaguc caagauccgc gcccuccucc gccucuacca ggagugcgag aagcucaaga      900

agcucauguc cuccaacucc accgaccucc cccucaacau cgagugcuuc augaacgaca      960

aggacgucuc cggcaagaug aaccgcuccc aguucgagga gcucugcgcc gagcuccucc     1020

agaagaucga ggucccccuc uacucccucc ucgagcagac ccaccucaag gucgaggacg     1080

ucuccgccgu cgagaucguc ggcggcgcca cccgcauccc cgccgucaag gagcgcaucg     1140

ccaaguucuu cggcaaggac aucuccacca cccucaacgc cgacgaggcc gucgcccgcg     1200

gcugcgcccu ccagugcgcc auccucuccc ccgccuucaa gguccgcgag uucuccguca     1260

ccgacgccgu ccccuucccc aucucccuca ucuggaacca cgacuccgag gacaccgagg     1320

gcguccacga ggucuucucc cgcaaccacg ccgcccccuu cuccaagguc cucaccuucc     1380

uccgccgcgg ccccuucgag cucgaggccu ucuacuccga cccccagggc guccccuacc     1440

ccgaggccaa gaucggccgc uucgucgucc agaacgucuc cgcccagaag gacggcgaga     1500

agucccgcgu caaggucaag guccgcguca acacccacgg caucuucacc aucuccaccg     1560

ccuccauggu cgagaagguc cccaccgagg agaacgagau guccuccgag gccgacaugg     1620

agugccucaa ccagcgcccc cccgagaacc ccgacaccga caagaacguc cagcaggaca     1680

acuccgaggc cggcacccag ccccaggucc agaccgacgc ccagcagacc ucccaguccc     1740

cccccucccc cgagcucacc uccgaggaga acaagauccc cgacgccgac aaggccaacg     1800

agaagaaggu cgaccagccc cccgaggcca agaagcccaa gaucaagguc gucaacgucg     1860

agcuccccau cgaggccaac cucgucuggc agcucggcaa ggaccuccuc aacauguaca     1920

ucgagaccga gggcaagaug aucaugcagg acaagcucga gaaggagcgc aacgacgcca     1980

agaacgccgu cgaggaguac gucuacgagu uccgcgacaa gcucugcggc cccuacgaga     2040

aguucaucug cgagcaggac caccagaacu uccuccgccu ccucaccgag accgaggacu     2100

ggcucuacga ggagggcgag gaccaggcca agcaggccua cgucgacaag cucgaggagc     2160

ucaugaagau cggcaccccc gucaaggucc gcuuccagga ggccgaggag cgccccaaga     2220

uguucgagga gcucggccag cgccuccagc acuacgccaa gaucgccgcc gacuuccgca     2280

acaaggacga gaaguacaac cacaucgacg aguccgagau gaagaagguc gagaaguccg     2340

ucaacgaggu cauggagugg augaacaacg ucaugaacgc ccaggccaag aagucccucg     2400

accaggaccc cgucguccgc gcccaggaga ucaagaccaa gaucaaggag cucaacaaca     2460

ccugcgagcc cgucgucacc cagcccaagc ccaagaucga gucccccaag cucgagcgca     2520

cccccaacgg ccccaacauc gacaagaagg aggaggaccu cgaggacaag aacaacuucg     2580

gcgccgagcc cccccaccag aacggcgagu gcuaccccaa cgagaagaac uccgucaaca     2640

uggaccucga cugaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  6473
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt2)

<400>  6473
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg uccgccgcca gcgcccccgc cgccgcgucu      120

gcugggcccu cgucgccguc cuccucgccg accuccucgc ccucuccgac acccucgccg      180

ucauguccgu cgaccucggc uccgagucca ugaaggucgc caucgucaag cccggcgucc      240

ccauggagau cguccucaac aaggaguccc gccgcaagac ccccgucauc gucacccuca      300

aggagaacga gcgcuucuuc ggcgacuccg ccgccuccau ggccaucaag aaccccaagg      360

ccacccuccg cuacuuccag caccuccucg gcaagcaggc cgacaacccc cacgucgccc      420

ucuaccaggc ccgcuucccc gagcacgagc ucaccuucga cccccagcgc cagaccgucc      480

acuuccagau cuccucccag cuccaguucu cccccgagga gguccucggc augguccuca      540

acuacucccg cucccucgcc gaggacuucg ccgagcagcc caucaaggac gccgucauca      600

ccguccccgu cuucuucaac caggccgagc gccgcgccgu ccuccaggcc gcccgcaugg      660

ccggccucaa gguccuccag cucaucaacg acaacaccgc caccgcccuc uccuacggcg      720

ucuuccgccg caaggacauc aacaccaccg cccagaacau cauguucuac gacaugggcu      780

ccggcuccac cgucugcacc aucgucaccu accagauggu caagaccaag gaggccggca      840

ugcagcccca gcuccagauc cgcggcgucg gcuucgaccg cacccucggc ggccucgaga      900

uggagcuccg ccuccgcgag cgccucgccg gccucuucaa cgagcagcgc aagggccagc      960

gcgccaagga cguccgcgag aacccccgcg ccauggccaa gcuccuccgc gaggccaacc     1020

gccucaagac cguccucucc gccaacgccg accacauggc ccagaucgag ggccucaugg     1080

acgacgucga cuucaaggcc aaggucaccc gcgucgaguu cgaggagcuc ugcgccgacc     1140

ucuucgagcg cguccccggc cccguccagc aggcccucca guccgccgag augucccucg     1200

acgagaucga gcaggucauc cucgucggcg gcgccacccg cgucccccgc guccaggagg     1260

uccuccucaa ggccgucggc aaggaggagc ucggcaagaa caucaacgcc gacgaggccg     1320

ccgccauggg cgccgucuac caggccgccg cccucuccaa ggccuucaag gucaagcccu     1380

ucgucguccg cgacgccguc gucuacccca uccucgucga guucacccgc gaggucgagg     1440

aggagcccgg cauccacucc cucaagcaca acaagcgcgu ccucuucucc cgcaugggcc     1500

ccuaccccca gcgcaagguc aucaccuuca accgcuacuc ccacgacuuc aacuuccaca     1560

ucaacuacgg cgaccucggc uuccucggcc ccgaggaccu ccgcgucuuc ggcucccaga     1620

accucaccac cgucaagcuc aagggcgucg gcgacuccuu caagaaguac cccgacuacg     1680

aguccaaggg caucaaggcc cacuucaacc ucgacgaguc cggcguccuc ucccucgacc     1740

gcgucgaguc cgucuucgag acccucgucg aggacuccgc cgaggaggag uccacccuca     1800

ccaagcucgg caacaccauc uccucccucu ucggcggcgg caccaccccc gacgccaagg     1860

agaacggcac cgacaccguc caggaggagg aggagucccc cgccgagggc uccaaggacg     1920

agcccggcga gcaggucgag cucaaggagg aggccgaggc ccccgucgag gacggcuccc     1980

agcccccccc ccccgagccc aagggcgacg ccacccccga gggcgagaag gccaccgaga     2040

aggagaacgg cgacaagucc gaggcccaga agcccuccga gaaggccgag gccggccccg     2100

agggcgucgc ccccgccccc gagggcgaga agaagcagaa gcccgcccgc aagcgccgca     2160

uggucgagga gaucggcguc gagcucgucg uccucgaccu ccccgaccuc cccgaggaca     2220

agcucgccca guccguccag aagcuccagg accucacccu ccgcgaccuc gagaagcagg     2280

agcgcgagaa ggccgccaac ucccucgagg ccuucaucuu cgagacccag gacaagcucu     2340

accagcccga guaccaggag gucuccaccg aggagcagcg cgaggagauc uccggcaagc     2400

ucuccgccgc cuccaccugg cucgaggacg agggcgucgg cgccaccacc gucaugcuca     2460

aggagaagcu cgccgagcuc cgcaagcucu gccagggccu cuucuuccgc gucgaggagc     2520

gcaagaagug gcccgagcgc cucuccgccc ucgacaaccu ccucaaccac uccuccaugu     2580

uccucaaggg cgcccgccuc auccccgaga uggaccagau cuucaccgag gucgagauga     2640

ccacccucga gaaggucauc aacgagaccu gggccuggaa gaacgccacc cucgccgagc     2700

aggccaagcu ccccgccacc gagaagcccg uccuccucuc caaggacauc gaggccaaga     2760

ugauggcccu cgaccgcgag guccaguacc uccucaacaa ggccaaguuc accaagcccc     2820

gcccccgccc caaggacaag aacggcaccc gcgccgagcc cccccucaac gccuccgccu     2880

ccgaccaggg cgagaagguc aucccccccg ccggccagac cgaggacgcc gagcccaucu     2940

ccgagcccga gaaggucgag accggcuccg agcccggcga caccgagccc cucgagcucg     3000

gcggccccgg cgccgagccc gagcagaagg agcaguccac cggccagaag cgcccccuca     3060

agaacgacga gcucugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6474
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt2)

<400>  6474
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaga cccagaccca ggaccagccc auggaggagg      120

aggaggucga gaccuucgcc uuccaggccg agaucgccca gcucaugucc cucaucauca      180

acaccuucua cuccaacaag gagaucuucc uccgcgagcu caucuccaac uccuccgacg      240

cccucgacaa gauccgcuac gagucccuca ccgaccccuc caagcucgac uccggcaagg      300

agcuccacau caaccucauc cccaacaagc aggaccgcac ccucaccauc gucgacaccg      360

gcaucggcau gaccaaggcc gaccucauca acaaccucgg caccaucgcc aaguccggca      420

ccaaggccuu cauggaggcc cuccaggccg gcgccgacau cuccaugauc ggccaguucg      480

gcgucggcuu cuacuccgcc uaccucgucg ccgagaaggu caccgucauc accaagcaca      540

acgacgacga gcaguacgcc ugggaguccu ccgccggcgg cuccuucacc guccgcaccg      600

acaccggcga gcccaugggc cgcggcacca aggucauccu ccaccucaag gaggaccaga      660

ccgaguaccu cgaggagcgc cgcaucaagg agaucgucaa gaagcacucc caguucaucg      720

gcuaccccau cacccucuuc gucgagaagg agcgcgacaa ggaggucucc gacgacgagg      780

ccgaggagaa ggaggacaag gaggaggaga aggagaagga ggagaaggag uccgaggaca      840

agcccgagau cgaggacguc ggcuccgacg aggaggagga gaagaaggac ggcgacaaga      900

agaagaagaa gaagaucaag gagaaguaca ucgaccagga ggagcucaac aagaccaagc      960

ccaucuggac ccgcaacccc gacgacauca ccaacgagga guacggcgag uucuacaagu     1020

cccucaccaa cgacugggag gaccaccucg ccgucaagca cuucuccguc gagggccagc     1080

ucgaguuccg cgcccuccuc uucguccccc gccgcgcccc cuucgaccuc uucgagaacc     1140

gcaagaagaa gaacaacauc aagcucuacg uccgccgcgu cuucaucaug gacaacugcg     1200

aggagcucau ccccgaguac cucaacuuca uccgcggcgu cgucgacucc gaggaccucc     1260

cccucaacau cucccgcgag augcuccagc aguccaagau ccucaagguc auccgcaaga     1320

accucgucaa gaagugccuc gagcucuuca ccgagcucgc cgaggacaag gagaacuaca     1380

agaaguucua cgagcaguuc uccaagaaca ucaagcucgg cauccacgag gacucccaga     1440

accgcaagaa gcucuccgag cuccuccgcu acuacaccuc cgccuccggc gacgagaugg     1500

ucucccucaa ggacuacugc acccgcauga aggagaacca gaagcacauc uacuacauca     1560

ccggcgagac caaggaccag gucgccaacu ccgccuucgu cgagcgccuc cgcaagcacg     1620

gccucgaggu caucuacaug aucgagccca ucgacgagua cugcguccag cagcucaagg     1680

aguucgaggg caagacccuc gucuccguca ccaaggaggg ccucgagcuc cccgaggacg     1740

aggaggagaa gaagaagcag gaggagaaga agaccaaguu cgagaaccuc ugcaagauca     1800

ugaaggacau ccucgagaag aaggucgaga aggucgucgu cuccaaccgc cucgucaccu     1860

cccccugcug caucgucacc uccaccuacg gcuggaccgc caacauggag cgcaucauga     1920

aggcccaggc ccuccgcgac aacuccacca ugggcuacau ggccgccaag aagcaccucg     1980

agaucaaccc cgaccacucc aucaucgaga cccuccgcca gaaggccgag gccgacaaga     2040

acgacaaguc cgucaaggac cucgucaucc uccucuacga gaccgcccuc cucuccuccg     2100

gcuucucccu cgaggacccc cagacccacg ccaaccgcau cuaccgcaug aucaagcucg     2160

gccucggcau cgacgaggac gaccccaccg ccgacgacac cuccgccgcc gucaccgagg     2220

agaugccccc ccucgagggc gacgacgaca ccucccgcau ggaggagguc gacugaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  6475
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt2)

<400>  6475
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccucca agcucgacuc cggcaagggc cuccacauca      120

accucguccc caacaagcag aaccagaccc ucaccaucgu cgacacccgc aucggcauga      180

ccaagaccga ccucaucaac aaccucggca ccgucaccaa guccggcacc aaggccuuca      240

uggaggcccu ccaggccgac gccgacaucu ccaugaucgg ccacuucggc gucggcuucu      300

acuccgccua ccucgucgcc aagaagguca ccgucaucuc caagcacaac aacgacgagc      360

aguacaccug ggaguccucc gccggcggcu ccuucaccgu ccgcaccgac gagugaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  6476
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt2)

<400>  6476
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggagg uccaccacgg cgaggaggag gucgagaccu      120

ucgccuucca ggccgagauc gcccagcuca ugucccucau caucaacacc uucuacucca      180

acaaggagau cuuccuccgc gagcucaucu ccaacgccuc cgacgcccuc gacaagaucc      240

gcuacgaguc ccucaccgac cccuccaagc ucgacuccgg caaggagcuc aagaucgaca      300

ucauccccaa cccccaggag cgcacccuca cccucgucga caccggcauc ggcaugacca      360

aggccgaccu caucaacaac cucggcacca ucgccaaguc cggcaccaag gccuucaugg      420

aggcccucca ggccggcgcc gacaucucca ugaucggcca guucggcguc ggcuucuacu      480

ccgccuaccu cgucgccgag aaggucgucg ucaucaccaa gcacaacgac gacgagcagu      540

acgccuggga guccuccgcc ggcggcuccu ucaccguccg cgccgaccac ggcgagccca      600

ucggccgcgg caccaagguc auccuccacc ucaaggagga ccagaccgag uaccucgagg      660

agcgccgcgu caaggagguc gucaagaagc acucccaguu caucggcuac cccaucaccc      720

ucuaccucga gaaggagcgc gagaaggaga ucuccgacga cgaggccgag gaggagaagg      780

gcgagaagga ggaggaggac aaggacgacg aggagaagcc caagaucgag gacgucggcu      840

ccgacgagga ggacgacucc ggcaaggaca agaagaagaa gaccaagaag aucaaggaga      900

aguacaucga ccaggaggag cucaacaaga ccaagcccau cuggacccgc aaccccgacg      960

acaucaccca ggaggaguac ggcgaguucu acaagucccu caccaacgac ugggaggacc     1020

accucgccgu caagcacuuc uccgucgagg gccagcucga guuccgcgcc cuccucuuca     1080

ucccccgccg cgcccccuuc gaccucuucg agaacaagaa gaagaagaac aacaucaagc     1140

ucuacguccg ccgcgucuuc aucauggacu ccugcgacga gcucaucccc gaguaccuca     1200

acuucauccg cggcgucguc gacuccgagg accucccccu caacaucucc cgcgagaugc     1260

uccagcaguc caagauccuc aaggucaucc gcaagaacau cgucaagaag ugccucgagc     1320

ucuucuccga gcucgccgag gacaaggaga acuacaagaa guucuacgag gccuucucca     1380

agaaccucaa gcucggcauc cacgaggacu ccaccaaccg ccgccgccuc uccgagcucc     1440

uccgcuacca caccucccag uccggcgacg agaugaccuc ccucuccgag uacgucuccc     1500

gcaugaagga gacccagaag uccaucuacu acaucaccgg cgaguccaag gagcaggucg     1560

ccaacuccgc cuucgucgag cgcguccgca agcgcggcuu cgaggucguc uacaugaccg     1620

agcccaucga cgaguacugc guccagcagc ucaaggaguu cgacggcaag ucccucgucu     1680

ccgucaccaa ggagggccuc gagcuccccg aggacgagga ggagaagaag aagauggagg     1740

aguccaaggc caaguucgag aaccucugca agcucaugaa ggagauccuc gacaagaagg     1800

ucgagaaggu caccaucucc aaccgccucg ucuccucccc cugcugcauc gucaccucca     1860

ccuacggcug gaccgccaac auggagcgca ucaugaaggc ccaggcccuc cgcgacaacu     1920

ccaccauggg cuacaugaug gccaagaagc accucgagau caaccccgac caccccaucg     1980

ucgagacccu ccgccagaag gccgaggccg acaagaacga caaggccguc aaggaccucg     2040

ucguccuccu cuucgagacc gcccuccucu ccuccggcuu cucccucgag gacccccaga     2100

cccacuccaa ccgcaucuac cgcaugauca agcucggccu cggcaucgac gaggacgagg     2160

ucgccgccga ggagcccaac gccgccgucc ccgacgagau ccccccccuc gagggcgacg     2220

aggacgccuc ccgcauggag gaggucgacu gaggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  6477
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt2)

<400>  6477
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcgcccucu ggguccucgg ccucugcugc guccuccuca      120

ccuucggcuc cguccgcgcc gacgacgagg ucgacgucga cggcaccguc gaggaggacc      180

ucggcaaguc ccgcgagggc ucccgcaccg acgacgaggu cguccagcgc gaggaggagg      240

ccauccagcu cgacggccuc aacgccuccc agauccgcga gcuccgcgag aaguccgaga      300

aguucgccuu ccaggccgag gucaaccgca ugaugaagcu caucaucaac ucccucuaca      360

agaacaagga gaucuuccuc cgcgagcuca ucuccaacgc cuccgacgcc cucgacaaga      420

uccgccucau cucccucacc gacgagaacg cccucuccgg caacgaggag cucaccguca      480

agaucaagug cgacaaggag aagaaccucc uccacgucac cgacaccggc gucggcauga      540

cccgcgagga gcucgucaag aaccucggca ccaucgccaa guccggcacc uccgaguucc      600

ucaacaagau gaccgaggcc caggaggacg gccaguccac cuccgagcuc aucggccagu      660

ucggcgucgg cuucuacucc gccuuccucg ucgccgacaa ggucaucguc accuccaagc      720

acaacaacga cacccagcac aucugggagu ccgacuccaa cgaguucucc gucaucgccg      780

acccccgcgg caacacccuc ggccgcggca ccaccaucac ccucguccuc aaggaggagg      840

ccuccgacua ccucgagcuc gacaccauca agaaccucgu caagaaguac ucccaguuca      900

ucaacuuccc caucuacguc ugguccucca agaccgagac cgucgaggag cccauggagg      960

aggaggaggc cgccaaggag gagaaggagg aguccgacga cgaggccgcc gucgaggagg     1020

aggaggagga gaagaagccc aagaccaaga aggucgagaa gaccgucugg gacugggagc     1080

ucaugaacga caucaagccc aucuggcagc gccccuccaa ggaggucgag gaggacgagu     1140

acaaggccuu cuacaagucc uucuccaagg aguccgacga ccccauggcc uacauccacu     1200

ucaccgccga gggcgagguc accuucaagu ccauccucuu cguccccacc uccgcccccc     1260

gcggccucuu cgacgaguac ggcuccaaga aguccgacua caucaagcuc uacguccgcc     1320

gcgucuucau caccgacgac uuccacgaca ugaugcccaa guaccucaac uucgucaagg     1380

gcgucgucga cuccgacgac cucccccuca acgucucccg cgagacccuc cagcagcaca     1440

agcuccucaa ggucauccgc aagaagcucg uccgcaagac ccucgacaug aucaagaaga     1500

ucgccgacga caaguacaac gacaccuucu ggaaggaguu cggcaccaac aucaagcucg     1560

gcgucaucga ggaccacucc aaccgcaccc gccucgccaa gcuccuccgc uuccaguccu     1620

cccaccaccc caccgacauc accucccucg accaguacgu cgagcgcaug aaggagaagc     1680

aggacaagau cuacuucaug gccggcuccu cccgcaagga ggccgagucc ucccccuucg     1740

ucgagcgccu ccucaagaag ggcuacgagg ucaucuaccu caccgagccc gucgacgagu     1800

acugcaucca ggcccucccc gaguucgacg gcaagcgcuu ccagaacguc gccaaggagg     1860

gcgucaaguu cgacgagucc gagaagacca aggagucccg cgaggccguc gagaaggagu     1920

ucgagccccu ccucaacugg augaaggaca aggcccucaa ggacaagauc gagaaggccg     1980

ucgucuccca gcgccucacc gagucccccu gcgcccucgu cgccucccag uacggcuggu     2040

ccggcaacau ggagcgcauc augaaggccc aggccuacca gaccggcaag gacaucucca     2100

ccaacuacua cgccucccag aagaagaccu ucgagaucaa cccccgccac ccccucaucc     2160

gcgacaugcu ccgccgcauc aaggaggacg aggacgacaa gaccguccuc gaccucgccg     2220

ucguccucuu cgagaccgcc acccuccgcu ccggcuaccu ccuccccgac accaaggccu     2280

acggcgaccg caucgagcgc augcuccgcc ucucccucaa caucgacccc gacgccaagg     2340

ucgaggagga gcccgaggag gagcccgagg agaccgccga ggacaccacc gaggacaccg     2400

agcaggacga ggacgaggag auggacgucg gcaccgacga ggaggaggag accgccaagg     2460

aguccaccgc cgagaaggac gagcucugag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  6478
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt2)

<400>  6478
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgcgagc uccgcgcccu ccuccucugg ggccgccgcc      120

uccgcccccu ccuccgcgcc cccgcccucg ccgccguccc cggcggcaag cccauccucu      180

gcccccgccg caccaccgcc cagcucggcc cccgccgcaa ccccgccugg ucccuccagg      240

ccggccgccu cuucuccacc cagaccgccg aggacaagga ggagccccuc cacuccauca      300

ucuccuccac cgaguccguc cagggcucca ccuccaagca cgaguuccag gccgagacca      360

agaagcuccu cgacaucguc gcccgcuccc ucuacuccga gaaggagguc uucauccgcg      420

agcucaucuc caacgccucc gacgcccucg agaagcuccg ccacaagcuc gucuccgacg      480

gccaggcccu ccccgagaug gagauccacc uccagaccaa cgccgagaag ggcaccauca      540

ccauccagga caccggcauc ggcaugaccc aggaggagcu cgucuccaac cucggcacca      600

ucgcccgcuc cggcuccaag gccuuccucg acgcccucca gaaccaggcc gaggccuccu      660

ccaagaucau cggccaguuc ggcgucggcu ucuacuccgc cuucaugguc gccgaccgcg      720

ucgaggucua cucccgcucc gccgcccccg gcucccucgg cuaccagugg cucuccgacg      780

gcuccggcgu cuucgagauc gccgaggccu ccggcguccg caccggcacc aagaucauca      840

uccaccucaa guccgacugc aaggaguucu ccuccgaggc ccgcguccgc gacgucguca      900

ccaaguacuc caacuucguc uccuuccccc ucuaccucaa cggccgccgc augaacaccc      960

uccaggccau cuggaugaug gaccccaagg acguccgcga guggcagcac gaggaguucu     1020

accgcuacgu cgcccaggcc cacgacaagc cccgcuacac ccuccacuac aagaccgacg     1080

ccccccucaa cauccgcucc aucuucuacg uccccgacau gaagcccucc auguucgacg     1140

ucucccgcga gcucggcucc uccgucgccc ucuacucccg caagguccuc auccagacca     1200

aggccaccga cauccucccc aaguggcucc gcuucauccg cggcgucguc gacuccgagg     1260

acaucccccu caaccucucc cgcgagcucc uccaggaguc cgcccucauc cgcaagcucc     1320

gcgacguccu ccagcagcgc cucaucaagu ucuucaucga ccaguccaag aaggacgccg     1380

agaaguacgc caaguucuuc gaggacuacg gccucuucau gcgcgagggc aucgucaccg     1440

ccaccgagca ggaggucaag gaggacaucg ccaagcuccu ccgcuacgag uccuccgccc     1500

uccccuccgg ccagcucacc ucccucuccg aguacgccuc ccgcaugcgc gccggcaccc     1560

gcaacaucua cuaccucugc gcccccaacc gccaccucgc cgagcacucc cccuacuacg     1620

aggccaugaa gaagaaggac accgaggucc ucuucugcuu cgagcaguuc gacgagcuca     1680

cccuccucca ccuccgcgag uucgacaaga agaagcucau cuccgucgag accgacaucg     1740

ucgucgacca cuacaaggag gagaaguucg aggaccgcuc ccccgccgcc gagugccucu     1800

ccgagaagga gaccgaggag cucauggccu ggaugcgcaa cguccucggc ucccgcguca     1860

ccaacgucaa ggucacccuc cgccucgaca cccaccccgc cauggucacc guccucgaga     1920

ugggcgccgc ccgccacuuc cuccgcaugc agcagcucgc caagacccag gaggagcgcg     1980

cccagcuccu ccagcccacc cucgagauca acccccgcca cgcccucauc aagaagcuca     2040

accagcuccg cgccuccgag cccggccucg cccagcuccu cgucgaccag aucuacgaga     2100

acgccaugau cgccgccggc cucgucgacg acccccgcgc cauggucggc cgccucaacg     2160

agcuccucgu caaggcccuc gagcgccacu gaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  6479
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt2)

<400>  6479
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagaucu ccucccuccc cacccagcuc uucaagugcu      120

gcuucugcga cuuccucaag gucaagaugc acaccauguc cuccucccac cucuucuacc      180

ucgcccucug ccuccucacc uucaccuccu ccgccaccgc cggccccgag acccucugcg      240

gcgccgagcu cgucgacgcc cuccaguucg ucugcggcga ccgcggcuuc uacuucaaca      300

agcccaccgg cuacggcucc uccucccgcc gcgcccccca gaccggcauc gucgacgagu      360

gcugcuuccg cuccugcgac cuccgccgcc ucgagaugua cugcgccccc cucaagcccg      420

ccaaguccgc ccgcuccguc cgcgcccagc gccacaccga caugcccaag acccagaagg      480

agguccaccu caagaacgcc ucccgcggcu ccgccggcaa caagaacuac cgcaugugag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  6480
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt2)

<400>  6480
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca ugggcaaguc caugcucguc cuccucaccu      120

uccucgccuu cgccuccugc ugcaucgccg ccuaccgccc cuccgagacc cucugcggcg      180

gcgagcucgu cgacacccuc caguucgucu gcggcgaccg cggcuucuac uucucccgcc      240

ccgccucccg cgucucccgc cgcucccgcg gcaucgucga ggagugcugc uuccgcuccu      300

gcgaccucgc ccuccucgag accuacugcg ccacccccgc caaguccgag cgcgacgucu      360

ccaccccccc caccguccuc cccgacaacu ucccccgcua ccccgucggc aaguucuucc      420

aguacgacac cuggaagcag uccacccagc gccuccgccg cggccucccc gcccuccucc      480

gcgcccgccg cggccacguc cucgccaagg agcucgaggc cuuccgcgag gccaagcgcc      540

accgcccccu caucgcccuc cccacccagg accccgccca cggcggcgcc ccccccgaga      600

uggccuccaa ccgcaaguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  6481
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt2)

<400>  6481
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccaccuccgc cuucggcccc gucgccuucu      120

cccucggccu ccuccucguc cuccccgccg ccuuccccgc ccccgucccc cccggcgagg      180

acuccaagga cgucgccgcc ccccaccgcc agccccucac cuccuccgag cgcaucgaca      240

agcagauccg cuacauccuc gacggcaucu ccgcccuccg caaggagacc ugcaacaagu      300

ccaacaugug cgaguccucc aaggaggccc ucgccgagaa caaccucaac cuccccaaga      360

uggccgagaa ggacggcugc uuccaguccg gcuucaacga ggagaccugc cucgucaaga      420

ucaucaccgg ccuccucgag uucgaggucu accucgagua ccuccagaac cgcuucgagu      480

ccuccgagga gcaggcccgc gccguccaga uguccaccaa gguccucauc caguuccucc      540

agaagaaggc caagaaccuc gacgccauca ccacccccga ccccaccacc aacgccuccc      600

uccucaccaa gcuccaggcc cagaaccagu ggcuccagga caugaccacc caccucaucc      660

uccgcuccuu caaggaguuc cuccaguccu cccuccgcgc ccuccgccag augugaggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  6482
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt2)

<400>  6482
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccucu ggcuccgcgg cuuccuccuc gccuccugcu      120

ggaucaucgu ccgcuccucc cccacccccg gcuccgaggg ccacuccgcc gcccccgacu      180

gccccuccug cgcccucgcc gcccucccca aggacguccc caacucccag cccgagaugg      240

ucgaggccgu caagaagcac auccucaaca ugcuccaccu caagaagcgc cccgacguca      300

cccagcccgu ccccaaggcc gcccuccuca acgccauccg caagcuccac gucggcaagg      360

ucggcgagaa cggcuacguc gagaucgagg acgacaucgg ccgccgcgcc gagaugaacg      420

agcucaugga gcagaccucc gagaucauca ccuucgccga guccggcacc gcccgcaaga      480

cccuccacuu cgagaucucc aaggagggcu ccgaccucuc cgucgucgag cgcgccgagg      540

ucuggcucuu ccucaagguc cccaaggcca accgcacccg caccaagguc accauccgcc      600

ucuuccagca gcagaagcac ccccagggcu cccucgacac cggcgaggag gccgaggagg      660

ucggccucaa gggcgagcgc uccgagcucc uccucuccga gaaggucguc gacgcccgca      720

aguccaccug gcacgucuuc cccgucuccu ccuccaucca gcgccuccuc gaccagggca      780

aguccucccu cgacguccgc aucgccugcg agcagugcca ggaguccggc gccucccucg      840

uccuccucgg caagaagaag aagaaggagg aggagggcga gggcaagaag aagggcggcg      900

gcgagggcgg cgccggcgcc gacgaggaga aggagcaguc ccaccgcccc uuccucaugc      960

uccaggcccg ccaguccgag gaccaccccc accgccgccg ccgccgcggc cucgagugcg     1020

acggcaaggu caacaucugc ugcaagaagc aguucuucgu cuccuucaag gacaucggcu     1080

ggaacgacug gaucaucgcc cccuccggcu accacgccaa cuacugcgag ggcgagugcc     1140

ccucccacau cgccggcacc uccggcuccu cccucuccuu ccacuccacc gucaucaacc     1200

acuaccgcau gcgcggccac ucccccuucg ccaaccucaa guccugcugc guccccacca     1260

agcuccgccc cauguccaug cucuacuacg acgacggcca gaacaucauc aagaaggaca     1320

uccagaacau gaucgucgag gagugcggcu gcuccugagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  6483
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt2)

<400>  6483
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccucc ccggccgcgc ccucggcgcc gccugccucc      120

uccuccucgc cgccggcugg cucggccccg aggccugggg cucccccacc ccccccccca      180

cccccgccgc cccccccccc cccccccccc ccggcucccc cggcggcucc caggacaccu      240

gcaccuccug cggcggcuuc cgccgccccg aggagcucgg ccgcgucgac ggcgacuucc      300

ucgaggccgu caagcgccac auccucuccc gccuccagau gcgcggccgc cccaacauca      360

cccacgccgu ccccaaggcc gccaugguca ccgcccuccg caagcuccac gccggcaagg      420

uccgcgagga cggccgcguc gagauccccc accucgacgg ccacgccucc cccggcgccg      480

acggccagga gcgcgucucc gagaucaucu ccuucgccga gaccgacggc cucgccuccu      540

cccgcguccg ccucuacuuc uucaucucca acgagggcaa ccagaaccuc uucgucgucc      600

aggccucccu cuggcucuac cucaagcucc uccccuacgu ccucgagaag ggcucccgcc      660

gcaagguccg cgucaagguc uacuuccagg agcagggcca cggcgaccgc uggaacaugg      720

ucgagaagcg cgucgaccuc aagcgcuccg gcuggcacac cuucccccuc accgaggcca      780

uccaggcccu cuucgagcgc ggcgagcgcc gccucaaccu cgacguccag ugcgacuccu      840

gccaggagcu cgccgucguc cccgucuucg ucgaccccgg cgaggagucc caccgccccu      900

ucgucgucgu ccaggcccgc cucggcgacu cccgccaccg cauccgcaag cgcggccucg      960

agugcgacgg ccgcaccaac cucugcugcc gccagcaguu cuucaucgac uuccgccuca     1020

ucggcuggaa cgacuggauc aucgccccca ccggcuacua cggcaacuac ugcgagggcu     1080

ccugccccgc cuaccucgcc ggcguccccg gcuccgccuc cuccuuccac accgccgucg     1140

ucaaccagua ccgcaugcgc ggccucaacc ccggcaccgu caacuccugc ugcaucccca     1200

ccaagcucuc caccaugucc augcucuacu ucgacgacga guacaacauc gucaagcgcg     1260

acguccccaa caugaucguc gaggagugcg gcugcgccug aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  6484
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt2)

<400>  6484
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccuccgcg uccuccuccu caccgcccuc acccucugcc      120

acggcuucaa ccucgacacc gagaacgcca ugaccuucca ggagaacgcc cgcggcuucg      180

gccaguccgu cguccagcuc cagggcuccc gcgucgucgu cggcgccccc caggagaucg      240

ucgccgccaa ccagcgcggc ucccucuacc agugcgacua cuccaccggc uccugcgagc      300

ccauccgccu ccaggucccc gucgaggccg ucaacauguc ccucggccuc ucccucgccg      360

ccaccaccuc ccccccccag cuccucgccu gcggccccac cguccaccag accugcuccg      420

agaacaccua cgucaagggc cucugcuucc ucuucggcuc caaccuccgc cagcagcccc      480

agaaguuccc cgaggcccuc cgcggcugcc cccaggagga cuccgacauc gccuuccuca      540

ucgacggcuc cggcuccauc aucccccacg acuuccgccg caugaaggag uucgucucca      600

ccgucaugga gcagcucaag aaguccaaga cccucuucuc ccucaugcag uacuccgagg      660

aguuccgcau ccacuucacc uucaaggagu uccagaacaa ccccaacccc cgcucccucg      720

ucaagcccau cacccagcuc cucggccgca cccacaccgc caccggcauc cgcaaggucg      780

uccgcgagcu cuucaacauc accaacggcg cccgcaagaa cgccuucaag auccucgucg      840

ucaucaccga cggcgagaag uucggcgacc cccucggcua cgaggacguc auccccgagg      900

ccgaccgcga gggcgucauc cgcuacguca ucggcgucgg cgacgccuuc cgcuccgaga      960

agucccgcca ggagcucaac accaucgccu ccaagccccc ccgcgaccac gucuuccagg     1020

ucaacaacuu cgaggcccuc aagaccaucc agaaccagcu ccgcgagaag aucuucgcca     1080

ucgagggcac ccagaccggc uccuccuccu ccuucgagca cgagaugucc caggagggcu     1140

ucuccgccgc caucaccucc aacggccccc uccucuccac cgucggcucc uacgacuggg     1200

ccggcggcgu cuuccucuac accuccaagg agaaguccac cuucaucaac augacccgcg     1260

ucgacuccga caugaacgac gccuaccucg gcuacgccgc cgccaucauc cuccgcaacc     1320

gcguccaguc ccucguccuc ggcgcccccc gcuaccagca caucggccuc gucgccaugu     1380

uccgccagaa caccggcaug ugggagucca acgccaacgu caagggcacc cagaucggcg     1440

ccuacuucgg cgccucccuc ugcuccgucg acgucgacuc caacggcucc accgaccucg     1500

uccucaucgg cgccccccac uacuacgagc agacccgcgg cggccagguc uccgucugcc     1560

cccucccccg cggccgcgcc cgcuggcagu gcgacgccgu ccucuacggc gagcagggcc     1620

agcccugggg ccgcuucggc gccgcccuca ccguccucgg cgacgucaac ggcgacaagc     1680

ucaccgacgu cgccaucggc gcccccggcg aggaggacaa ccgcggcgcc gucuaccucu     1740

uccacggcac cuccggcucc ggcaucuccc ccucccacuc ccagcgcauc gccggcucca     1800

agcucucccc ccgccuccag uacuucggcc agucccucuc cggcggccag gaccucacca     1860

uggacggccu cgucgaccuc accgucggcg cccagggcca cguccuccuc cuccgcuccc     1920

agcccguccu ccgcgucaag gccaucaugg aguucaaccc ccgcgagguc gcccgcaacg     1980

ucuucgagug caacgaccag gucgucaagg gcaaggaggc cggcgagguc cgcgucugcc     2040

uccacgucca gaaguccacc cgcgaccgcc uccgcgaggg ccagauccag uccgucguca     2100

ccuacgaccu cgcccucgac uccggccgcc cccacucccg cgccgucuuc aacgagacca     2160

agaacuccac ccgccgccag acccaggucc ucggccucac ccagaccugc gagacccuca     2220

agcuccagcu ccccaacugc aucgaggacc ccgucucccc caucguccuc cgccucaacu     2280

ucucccucgu cggcaccccc cucuccgccu ucggcaaccu ccgccccguc cucgccgagg     2340

acgcccagcg ccucuucacc gcccucuucc ccuucgagaa gaacugcggc aacgacaaca     2400

ucugccagga cgaccucucc aucaccuucu ccuucauguc ccucgacugc cucgucgucg     2460

gcggcccccg cgaguucaac gucaccguca ccguccgcaa cgacggcgag gacuccuacc     2520

gcacccaggu caccuucuuc uucccccucg accucuccua ccgcaagguc uccacccucc     2580

agaaccagcg cucccagcgc uccuggcgcc ucgccugcga guccgccucc uccaccgagg     2640

ucuccggcgc ccucaagucc accuccugcu ccaucaacca ccccaucuuc cccgagaacu     2700

ccgaggucac cuucaacauc accuucgacg ucgacuccaa ggccucccuc ggcaacaagc     2760

uccuccucaa ggccaacguc accuccgaga acaacaugcc ccgcaccaac aagaccgagu     2820

uccagcucga gcuccccguc aaguacgccg ucuacauggu cgucaccucc cacggcgucu     2880

ccaccaagua ccucaacuuc accgccuccg agaacaccuc ccgcgucaug cagcaccagu     2940

accaggucuc caaccucggc cagcgcuccc uccccaucuc ccucgucuuc cucguccccg     3000

uccgccucaa ccagaccguc aucugggacc gcccccaggu caccuucucc gagaaccucu     3060

ccuccaccug ccacaccaag gagcgccucc ccucccacuc cgacuuccuc gccgagcucc     3120

gcaaggcccc cgucgucaac ugcuccaucg ccgucugcca gcgcauccag ugcgacaucc     3180

ccuucuucgg cauccaggag gaguucaacg ccacccucaa gggcaaccuc uccuucgacu     3240

gguacaucaa gaccucccac aaccaccucc ucaucgucuc caccgccgag auccucuuca     3300

acgacuccgu cuucacccuc cuccccggcc agggcgccuu cguccgcucc cagaccgaga     3360

ccaaggucga gcccuucgag guccccaacc cccucccccu caucgucggc uccuccgucg     3420

gcggccuccu ccuccucgcc cucaucaccg ccgcccucua caagcucggc uucuucaagc     3480

gccaguacaa ggacaugaug uccgagggcg gcccccccgg cgccgagccc cagugaggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  6485
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt2)

<400>  6485
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucccuca agacccuccc cuuccuccuc cuccuccacg      120

uccagaucuc caaggccuuc cccgucuccu ccaaggagaa gaacaccaag accguccagg      180

acuaccucga gaaguucuac cagcuccccu ccaaccagua ccaguccacc cgcaagaacg      240

gcaccaacgu caucgucgag aagcucaagg agaugcagcg cuucuucggc cucaacguca      300

ccggcaagcc caacgaggag acccucgaca ugaugaagaa gccccgcugc ggcguccccg      360

acuccggcgg cuucaugcuc acccccggca accccaagug ggagcgcacc aaccucaccu      420

accgcauccg caacuacacc ccccagcucu ccgaggccga ggucgagcgc gccaucaagg      480

acgccuucga gcucuggucc gucgccuccc cccucaucuu cacccgcauc ucccagggcg      540

aggccgacau caacaucgcc uucuaccagc gcgaccacgg cgacaacucc cccuucgacg      600

gccccaacgg cauccucgcc cacgccuucc agcccggcca gggcaucggc ggcgacgccc      660

acuucgacgc cgaggagacc uggaccaaca ccuccgccaa cuacaaccuc uuccucgucg      720

ccgcccacga guucggccac ucccucggcc ucgcccacuc cuccgacccc ggcgcccuca      780

uguaccccaa cuacgccuuc cgcgagaccu ccaacuacuc ccucccccag gacgacaucg      840

acggcaucca ggccaucuac ggccucuccu ccaaccccau ccagcccacc ggccccucca      900

cccccaagcc cugcgacccc ucccucaccu ucgacgccau caccacccuc cgcggcgaga      960

uccucuucuu caaggaccgc uacuucuggc gccgccaccc ccagcuccag cgcgucgaga     1020

ugaacuucau cucccucuuc uggcccuccc uccccaccgg cauccaggcc gccuacgagg     1080

acuucgaccg cgaccucauc uuccucuuca agggcaacca guacugggcc cucuccggcu     1140

acgacauccu ccagggcuac cccaaggaca ucuccaacua cggcuucccc uccuccgucc     1200

aggccaucga cgccgccguc uucuaccgcu ccaagaccua cuucuucguc aacgaccagu     1260

ucuggcgcua cgacaaccag cgccaguuca uggagcccgg cuaccccaag uccaucuccg     1320

gcgccuuccc cggcaucgag uccaaggucg acgccgucuu ccagcaggag cacuucuucc     1380

acgucuucuc cggcccccgc uacuacgccu ucgaccucau cgcccagcgc gucacccgcg     1440

ucgcccgcgg caacaagugg cucaacugcc gcuacggcug aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  6486
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt2)

<400>  6486
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucccucuggc agccccucgu ccucguccuc cucguccucg      120

gcugcugcuu cgccgccccc cgccagcgcc aguccacccu cguccucuuc cccggcgacc      180

uccgcaccaa ccucaccgac cgccagcucg ccgaggagua ccucuaccgc uacggcuaca      240

cccgcgucgc cgagaugcgc ggcgagucca agucccucgg ccccgcccuc cuccuccucc      300

agaagcagcu cucccucccc gagaccggcg agcucgacuc cgccacccuc aaggccaugc      360

gcaccccccg cugcggcguc cccgaccucg gccgcuucca gaccuucgag ggcgaccuca      420

aguggcacca ccacaacauc accuacugga uccagaacua cuccgaggac cucccccgcg      480

ccgucaucga cgacgccuuc gcccgcgccu ucgcccucug guccgccguc accccccuca      540

ccuucacccg cgucuacucc cgcgacgccg acaucgucau ccaguucggc gucgccgagc      600

acggcgacgg cuaccccuuc gacggcaagg acggccuccu cgcccacgcc uucccccccg      660

gccccggcau ccagggcgac gcccacuucg acgacgacga gcucuggucc cucggcaagg      720

gcgucgucgu ccccacccgc uucggcaacg ccgacggcgc cgccugccac uuccccuuca      780

ucuucgaggg ccgcuccuac uccgccugca ccaccgacgg ccgcuccgac ggccuccccu      840

ggugcuccac caccgccaac uacgacaccg acgaccgcuu cggcuucugc cccuccgagc      900

gccucuacac ccaggacggc aacgccgacg gcaagcccug ccaguucccc uucaucuucc      960

agggccaguc cuacuccgcc ugcaccaccg acggccgcuc cgacggcuac cgcuggugcg     1020

ccaccaccgc caacuacgac cgcgacaagc ucuucggcuu cugccccacc cgcgccgacu     1080

ccaccgucau gggcggcaac uccgccggcg agcucugcgu cuuccccuuc accuuccucg     1140

gcaaggagua cuccaccugc accuccgagg gccgcggcga cggccgccuc uggugcgcca     1200

ccaccuccaa cuucgacucc gacaagaagu ggggcuucug ccccgaccag ggcuacuccc     1260

ucuuccucgu cgccgcccac gaguucggcc acgcccucgg ccucgaccac uccuccgucc     1320

ccgaggcccu cauguacccc auguaccgcu ucaccgaggg ccccccccuc cacaaggacg     1380

acgucaacgg cauccgccac cucuacggcc cccgccccga gcccgagccc cgccccccca     1440

ccaccaccac cccccagccc accgcccccc ccaccgucug ccccaccggc ccccccaccg     1500

uccaccccuc cgagcgcccc accgccggcc ccaccggccc ccccuccgcc ggccccaccg     1560

gcccccccac cgccggcccc uccaccgcca ccaccguccc ccucuccccc gucgacgacg     1620

ccugcaacgu caacaucuuc gacgccaucg ccgagaucgg caaccagcuc uaccucuuca     1680

aggacggcaa guacuggcgc uucuccgagg gccgcggcuc ccgcccccag ggccccuucc     1740

ucaucgccga caaguggccc gcccuccccc gcaagcucga cuccgucuuc gaggagcgcc     1800

ucuccaagaa gcucuucuuc uucuccggcc gccaggucug ggucuacacc ggcgccuccg     1860

uccucggccc ccgccgccuc gacaagcucg gccucggcgc cgacgucgcc caggucaccg     1920

gcgcccuccg cuccggccgc ggcaagaugc uccucuucuc cggccgccgc cucuggcgcu     1980

ucgacgucaa ggcccagaug gucgaccccc gcuccgccuc cgaggucgac cgcauguucc     2040

ccggcguccc ccucgacacc cacgacgucu uccaguaccg cgagaaggcc uacuucugcc     2100

aggaccgcuu cuacuggcgc gucuccuccc gcuccgagcu caaccagguc gaccaggucg     2160

gcuacgucac cuacgacauc cuccagugcc ccgaggacug aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  6487
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt2)

<400>  6487
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg uccucgccgc cuuccucuuc cucuccugga      120

cccacugccg cgcccucccc cuccccuccg gcggcgacga ggacgaccuc uccgaggagg      180

accuccaguu cgccgagcgc uaccuccgcu ccuacuacca ccccaccaac cucgccggca      240

uccucaagga gaacgccgcc uccuccauga ccgagcgccu ccgcgagaug caguccuucu      300

ucggccucga ggucaccggc aagcucgacg acaacacccu cgacgucaug aagaagcccc      360

gcugcggcgu ccccgacguc ggcgaguaca acgucuuccc ccgcacccuc aaguggucca      420

agaugaaccu caccuaccgc aucgucaacu acacccccga caugacccac uccgaggucg      480

agaaggccuu caagaaggcc uucaaggucu gguccgacgu caccccccuc aacuucaccc      540

gccuccacga cggcaucgcc gacaucauga ucuccuucgg caucaaggag cacggcgacu      600

ucuaccccuu cgacggcccc uccggccucc ucgcccacgc cuuccccccc ggccccaacu      660

acggcggcga cgcccacuuc gacgacgacg agaccuggac cuccuccucc aagggcuaca      720

accucuuccu cgucgccgcc cacgaguucg gccacucccu cggccucgac cacuccaagg      780

accccggcgc ccucauguuc cccaucuaca ccuacaccgg caagucccac uucaugcucc      840

ccgacgacga cguccagggc auccaguccc ucuacggccc cggcgacgag gaccccaacc      900

ccaagcaccc caagaccccc gacaagugcg accccucccu cucccucgac gccaucaccu      960

cccuccgcgg cgagaccaug aucuucaagg accgcuucuu cuggcgccuc cacccccagc     1020

aggucgacgc cgagcucuuc cucaccaagu ccuucuggcc cgagcucccc aaccgcaucg     1080

acgccgccua cgagcacccc ucccacgacc ucaucuucau cuuccgcggc cgcaaguucu     1140

gggcccucaa cggcuacgac auccucgagg gcuaccccaa gaagaucucc gagcucggcc     1200

uccccaagga ggucaagaag aucuccgccg ccguccacuu cgaggacacc ggcaagaccc     1260

uccucuucuc cggcaaccag gucuggcgcu acgacgacac caaccacauc auggacaagg     1320

acuacccccg ccucaucgag gaggacuucc ccggcaucgg cgacaagguc gacgccgucu     1380

acgagaagaa cggcuacauc uacuucuuca acggccccau ccaguucgag uacuccaucu     1440

gguccaaccg caucguccgc gucaugcccg ccaacuccau ccucuggugc ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6488
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt2)

<400>  6488
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acaccaccga ggacuacgac accaccaccg      120

aguucgacua cggcgacgcc acccccugcc agaaggucaa cgagcgcgcc uucggcgccc      180

agcuccuccc cccccucuac ucccucgucu ucgucaucgg ccucgucggc aacauccucg      240

ucguccucgu ccucguccag uacaagcgcc ucaagaacau gaccuccauc uaccuccuca      300

accucgccau cuccgaccuc cucuuccucu ucacccuccc cuucuggauc gacuacaagc      360

ucaaggacga cugggucuuc ggcgacgcca ugugcaagau ccucuccggc uucuacuaca      420

ccggccucua cuccgagauc uucuucauca uccuccucac caucgaccgc uaccucgcca      480

ucguccacgc cgucuucgcc cuccgcgccc gcaccgucac cuucggcguc aucaccucca      540

ucaucaucug ggcccucgcc auccucgccu ccaugcccgg ccucuacuuc uccaagaccc      600

agugggaguu cacccaccac accugcuccc uccacuuccc ccacgagucc cuccgcgagu      660

ggaagcucuu ccaggcccuc aagcucaacc ucuucggccu cguccucccc cuccucguca      720

ugaucaucug cuacaccggc aucaucaaga uccuccuccg ccgccccaac gagaagaagu      780

ccaaggccgu ccgccucauc uucgucauca ugaucaucuu cuuccucuuc uggacccccu      840

acaaccucac cauccucauc uccgucuucc aggacuuccu cuucacccac gagugcgagc      900

agucccgcca ccucgaccuc gccguccagg ucaccgaggu caucgccuac acccacugcu      960

gcgucaaccc cgucaucuac gccuucgucg gcgagcgcuu ccgcaaguac cuccgccagc     1020

ucuuccaccg ccgcgucgcc guccaccucg ucaaguggcu ccccuuccuc uccgucgacc     1080

gccucgagcg cgucuccucc accucccccu ccaccggcga gcacgagcuc uccgccggcu     1140

ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  6489
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt2)

<400>  6489
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcacccucg ccugccuccu ccuccucggc ugcggcuacc      120

ucgcccacgu ccucgccgag gaggccgaga ucccccgcga ggucaucgag cgccucgccc      180

gcucccagau ccacuccauc cgcgaccucc agcgccuccu cgagaucgac uccgucggcu      240

ccgaggacuc ccucgacacc ucccuccgcg cccacggcgu ccacgccacc aagcacgucc      300

ccgagaagcg cccccucccc auccgccgca agcgcuccau cgaggaggcc guccccgccg      360

ucugcaagac ccgcaccguc aucuacgaga ucccccgcuc ccaggucgac cccaccuccg      420

ccaacuuccu caucuggccc cccugcgucg aggucaagcg cugcaccggc ugcugcaaca      480

ccuccuccgu caagugccag cccucccgcg uccaccaccg cuccgucaag gucgccaagg      540

ucgaguacgu ccgcaagaag cccaagcuca aggaggucca gguccgccuc gaggagcacc      600

ucgagugcgc cugcgccacc accucccuca accccgacua ccgcgaggag gacaccggcc      660

gcccccgcga guccggcaag aagcgcaagc gcaagcgccu caagcccacc ugaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  6490
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt2)

<400>  6490
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaccgcugcu gggcccucuu ccucucccuc ugcugcuacc      120

uccgccucgu cuccgccgag ggcgacccca uccccgagga gcucuacgag augcucuccg      180

accacuccau ccgcuccuuc gacgaccucc agcgccuccu ccacggcgac cccggcgagg      240

aggacggcgc cgagcucgac cucaacauga cccgcuccca cuccggcggc gagcucgagu      300

cccucgcccg cggccgccgc ucccucggcu cccucaccau cgccgagccc gccaugaucg      360

ccgagugcaa gacccgcacc gaggucuucg agaucucccg ccgccucauc gaccgcacca      420

acgccaacuu ccucgucugg ccccccugcg ucgaggucca gcgcugcucc ggcugcugca      480

acaaccgcaa cguccagugc cgccccaccc agguccagcu ccgccccguc cagguccgca      540

agaucgagau cguccgcaag aagcccaucu ucaagaaggc caccgucacc cucgaggacc      600

accucgccug caagugcgag accgucgccg ccgcccgccc cgucacccgc ucccccggcg      660

gcucccagga gcagcgcgcc aagacccccc agacccgcgu caccauccgc accguccgcg      720

uccgccgccc ccccaagggc aagcaccgca aguucaagca cacccacgac aagaccgccc      780

ucaaggagac ccucggcgcc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  6491
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt2)

<400>  6491
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucccucuucg gccuccuccu ccucaccucc gcccucgccg      120

gccagcgcca gggcacccag gccgagucca accucuccuc caaguuccag uucuccucca      180

acaaggagca gaacggcguc caggaccccc agcacgagcg caucaucacc gucuccacca      240

acggcuccau ccacuccccc cgcuuccccc acaccuaccc ccgcaacacc guccucgucu      300

ggcgccucgu cgccgucgag gagaacgucu ggauccagcu caccuucgac gagcgcuucg      360

gccucgagga ccccgaggac gacaucugca aguacgacuu cgucgagguc gaggagcccu      420

ccgacggcac cauccucggc cgcuggugcg gcuccggcac cguccccggc aagcagaucu      480

ccaagggcaa ccagauccgc auccgcuucg ucuccgacga guacuucccc uccgagcccg      540

gcuucugcau ccacuacaac aucgucaugc cccaguucac cgaggccguc ucccccuccg      600

uccucccccc cuccgcccuc ccccucgacc uccucaacaa cgccaucacc gccuucucca      660

cccucgagga ccucauccgc uaccucgagc ccgagcgcug gcagcucgac cucgaggacc      720

ucuaccgccc caccuggcag cuccucggca aggccuucgu cuucggccgc aagucccgcg      780

ucgucgaccu caaccuccuc accgaggagg uccgccucua cuccugcacc ccccgcaacu      840

ucuccgucuc cauccgcgag gagcucaagc gcaccgacac caucuucugg cccggcugcc      900

uccucgucaa gcgcugcggc ggcaacugcg ccugcugccu ccacaacugc aacgagugcc      960

agugcguccc cuccaagguc accaagaagu accacgaggu ccuccagcuc cgccccaaga     1020

ccggcguccg cggccuccac aagucccuca ccgacgucgc ccucgagcac cacgaggagu     1080

gcgacugcgu cugccgcggc uccaccggcg gcugaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  6492
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt2)

<400>  6492
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgccuca ucuucgucua cacccucauc ugcgccaacu      120

ucugcuccug ccgcgacacc uccgccaccc cccaguccgc cuccaucaag gcccuccgca      180

acgccaaccu ccgccgcgac gaccucuacc gccgcgacga gaccauccag gucaagggca      240

acggcuacgu ccaguccccc cgcuucccca acuccuaccc ccgcaaccuc cuccucaccu      300

ggcgccucca cucccaggag aacacccgca uccagcucgu cuucgacaac caguucggcc      360

ucgaggaggc cgagaacgac aucugccgcu acgacuucgu cgaggucgag gacaucuccg      420

agaccuccac caucauccgc ggccgcuggu gcggccacaa ggaggucccc ccccgcauca      480

agucccgcac caaccagauc aagaucaccu ucaaguccga cgacuacuuc gucgccaagc      540

ccggcuucaa gaucuacuac ucccuccucg aggacuucca gcccgccgcc gccuccgaga      600

ccaacuggga guccgucacc uccuccaucu ccggcgucuc cuacaacucc cccuccguca      660

ccgaccccac ccucaucgcc gacgcccucg acaagaagau cgccgaguuc gacaccgucg      720

aggaccuccu caaguacuuc aaccccgagu ccuggcagga ggaccucgag aacauguacc      780

ucgacacccc ccgcuaccgc ggccgcuccu accacgaccg caaguccaag gucgaccucg      840

accgccucaa cgacgacgcc aagcgcuacu ccugcacccc ccgcaacuac uccgucaaca      900

uccgcgagga gcucaagcuc gccaacgucg ucuucuuccc ccgcugccuc cucguccagc      960

gcugcggcgg caacugcggc ugcggcaccg ucaacuggcg cuccugcacc ugcaacuccg     1020

gcaagaccgu caagaaguac cacgaggucc uccaguucga gcccggccac aucaagcgcc     1080

gcggccgcgc caagaccaug gcccucgucg acauccagcu cgaccaccac gagcgcugcg     1140

acugcaucug cuccucccgc cccccccgcu gaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  6493
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt2)

<400>  6493
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccacu ccaaguuccc cgccgccggc augucccgcc      120

cccucgacac cucccuccgc cucaagaccu ucuccuccaa guccgaguac cagcucgucg      180

ucaacgccgu ccgcaagcuc caggaguccg gcuucuacug guccgccguc accggcggcg      240

aggccaaccu ccuccucucc gccgagcccg ccggcaccuu ccucauccgc gacuccuccg      300

accagcgcca cuucuucacc cucuccguca agacccaguc cggcaccaag aaccuccgca      360

uccagugcga gggcggcucc uucucccucc aguccgaccc ccgcuccacc cagcccgucc      420

cccgcuucga cugcguccuc aagcucgucc accacuacau gccccccccc ggcgcccccu      480

ccuuccccuc cccccccacc gagcccuccu ccgagguccc cgagcagccc uccgcccagc      540

cccuccccgg cucccccccc cgccgcgccu acuacaucua cuccggcggc gagaagaucc      600

cccucguccu cucccgcccc cucuccucca acgucgccac ccuccagcac cucugccgca      660

agaccgucaa cggccaccuc gacuccuacg agaaggucac ccagcucccc ggccccaucc      720

gcgaguuccu cgaccaguac gacgcccccc ucugaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  6494
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt2)

<400>  6494
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guccccuccg ccggccagcu cgcccucuuc gcccucggca      120

ucguccucgc cgccugccag gcccucgaga acuccaccuc cccccucucc gccgaccccc      180

ccgucgccgc cgccgucguc ucccacuuca acgacugccc cgacucccac acccaguucu      240

gcuuccacgg caccugccgc uuccucgucc aggaggacaa gcccgccugc gucugccacu      300

ccggcuacgu cggcgcccgc ugcgagcacg ccgaccuccu cgccgucguc gccgccuccc      360

agaagaagca ggccaucacc gcccucgucg ucgucuccau cgucgcccuc gccguccuca      420

ucaucaccug cguccucauc cacugcugcc agguccgcaa gcacugcgag uggugccgcg      480

cccucaucug ccgccacgag aagcccuccg cccuccucaa gggccgcacc gccugcugcc      540

acuccgagac cgucgucuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  6495
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt2)

<400>  6495
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccccuccg gccuccgccu ccucccccuc cuccuccccc      120

uccucuggcu ccucguccuc acccccggcc gccccgccgc cggccucucc accugcaaga      180

ccaucgacau ggagcucguc aagcgcaagc gcaucgaggc cauccgcggc cagauccucu      240

ccaagcuccg ccucgccucc ccccccuccc agggcgaggu cccccccggc ccccuccccg      300

aggccguccu cgcccucuac aacuccaccc gcgaccgcgu cgccggcgag uccgccgagc      360

ccgagcccga gcccgaggcc gacuacuacg ccaaggaggu cacccgcguc cucauggucg      420

agacccacaa cgagaucuac gacaaguuca agcaguccac ccacuccauc uacauguucu      480

ucaacaccuc cgagcuccgc gaggccgucc ccgagcccgu ccuccucucc cgcgccgagc      540

uccgccuccu ccgccucaag cucaaggucg agcagcacgu cgagcucuac cagaaguacu      600

ccaacaacuc cuggcgcuac cucuccaacc gccuccucgc ccccuccgac ucccccgagu      660

ggcucuccuu cgacgucacc ggcgucgucc gccaguggcu cucccgcggc ggcgagaucg      720

agggcuuccg ccucuccgcc cacugcuccu gcgacucccg cgacaacacc cuccaggucg      780

acaucaacgg cuucaccacc ggccgccgcg gcgaccucgc caccauccac ggcaugaacc      840

gccccuuccu ccuccucaug gccacccccc ucgagcgcgc ccagcaccuc caguccuccc      900

gccaccgccg cgcccucgac accaacuacu gcuucuccuc caccgagaag aacugcugcg      960

uccgccagcu cuacaucgac uuccgcaagg accucggcug gaaguggauc cacgagccca     1020

agggcuacca cgccaacuuc ugccucggcc ccugccccua caucuggucc cucgacaccc     1080

aguacuccaa gguccucgcc cucuacaacc agcacaaccc cggcgccucc gccgcccccu     1140

gcugcguccc ccaggcccuc gagccccucc ccaucgucua cuacgucggc cgcaagccca     1200

aggucgagca gcucuccaac augaucgucc gcuccugcaa gugcuccuga ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  6496
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt2)

<400>  6496
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uccucuccgc cuuccucauc cuccaccucg      120

ucaccgucgc ccucucccuc uccaccugcu ccacccucga cauggaccag uucaugcgca      180

agcgcaucga ggccauccgc ggccagaucc ucuccaagcu caagcucacc uccccccccg      240

aggacuaccc cgagcccgag gagguccccc ccgaggucau cuccaucuac aacuccaccc      300

gcgaccuccu ccaggagaag gccucccgcc gcgccgccgc cugcgagcgc gagcgcuccg      360

acgaggagua cuacgccaag gaggucuaca agaucgacau gccccccuuc uuccccuccg      420

agaacgccau cccccccacc uucuaccgcc ccuacuuccg caucguccgc uucgacgucu      480

ccgccaugga gaagaacgcc uccaaccucg ucaaggccga guuccgcguc uuccgccucc      540

agaaccccaa ggcccgcguc cccgagcagc gcaucgagcu cuaccagauc cucaagucca      600

aggaccucac cucccccacc cagcgcuaca ucgacuccaa ggucgucaag acccgcgccg      660

agggcgagug gcucuccuuc gacgucaccg acgccgucca cgaguggcuc caccacaagg      720

accgcaaccu cggcuucaag aucucccucc acugccccug cugcaccuuc guccccucca      780

acaacuacau cauccccaac aaguccgagg agcucgaggc ccgcuucgcc ggcaucgacg      840

gcaccuccac cuacaccucc ggcgaccaga agaccaucaa guccacccgc aagaagaacu      900

ccggcaagac cccccaccuc cuccucaugc uccuccccuc cuaccgccuc gagucccagc      960

agaccaaccg ccgcaagaag cgcgcccucg acgccgccua cugcuuccgc aacguccagg     1020

acaacugcug ccuccgcccc cucuacaucg acuucaagcg cgaccucggc uggaagugga     1080

uccacgagcc caagggcuac aacgccaacu ucugcgccgg cgccugcccc uaccucuggu     1140

ccuccgacac ccagcacucc cgcguccucu cccucuacaa caccaucaac cccgaggccu     1200

ccgccucccc cugcugcguc ucccaggacc ucgagccccu caccauccuc uacuacaucg     1260

gcaagacccc caagaucgag cagcucucca acaugaucgu caaguccugc aagugcuccu     1320

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  6497
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt2)

<400>  6497
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacc uccagcgcgc ccucgucguc cucgcccucc      120

ucaacuucgc caccgucucc cucucccucu ccaccugcac cacccucgac uucggccaca      180

ucaagaagaa gcgcgucgag gccauccgcg gccagauccu cuccaagcuc cgccucaccu      240

ccccccccga gcccaccguc augacccacg uccccuacca gguccucgcc cucuacaacu      300

ccacccgcga gcuccucgag gagaugcacg gcgagcgcga ggagggcugc acccaggaga      360

acaccgaguc cgaguacuac gccaaggaga uccacaaguu cgacaugauc cagggccucg      420

ccgagcacaa cgagcucgcc gucugcccca agggcaucac cuccaagguc uuccgcuuca      480

acgucuccuc cgucgagaag aaccgcacca accucuuccg cgccgaguuc cgcguccucc      540

gcguccccaa ccccuccucc aagcgcaacg agcagcgcau cgagcucuuc cagauccucc      600

gccccgacga gcacaucgcc aagcagcgcu acaucggcgg caagaaccuc cccacccgcg      660

gcaccgccga guggcucucc uucgacguca ccgacaccgu ccgcgagugg cuccuccgcc      720

gcgaguccaa ccucggccuc gagaucucca uccacugccc cugccacacc uuccagccca      780

acggcgacau ccucgagaac auccacgagg ucauggagau caaguucaag ggcgucgaca      840

acgaggacga ccacggccgc ggcgaccucg gccgccucaa gaagcagaag gaccaccaca      900

acccccaccu cauccucaug augauccccc cccaccgccu cgacaacccc ggccagggcg      960

gccagcgcaa gaagcgcgcc cucgacacca acuacugcuu ccgcaaccuc gaggagaacu     1020

gcugcguccg cccccucuac aucgacuucc gccaggaccu cggcuggaag uggguccacg     1080

agcccaaggg cuacuacgcc aacuucugcu ccggccccug ccccuaccuc cgcuccgccg     1140

acaccaccca cuccaccguc cucggccucu acaacacccu caaccccgag gccuccgccu     1200

cccccugcug cgucccccag gaccucgagc cccucaccau ccucuacuac gucggccgca     1260

cccccaaggu cgagcagcuc uccaacaugg ucgucaaguc cugcaagugc uccugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6498
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt2)

<400>  6498
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccccgucg ccgucugggc cgcccucgcc gucggccucg      120

agcucugggc cgccgcccac gcccuccccg cccaggucgc cuucaccccc uacgcccccg      180

agcccggcuc caccugccgc cuccgcgagu acuacgacca gaccgcccag augugcugcu      240

ccaagugcuc ccccggccag cacgccaagg ucuucugcac caagaccucc gacaccgucu      300

gcgacuccug cgaggacucc accuacaccc agcucuggaa cugggucccc gagugccucu      360

ccugcggcuc ccgcugcucc uccgaccagg ucgagaccca ggccugcacc cgcgagcaga      420

accgcaucug caccugccgc cccggcuggu acugcgcccu cuccaagcag gagggcugcc      480

gccucugcgc cccccuccgc aagugccgcc ccggcuucgg cgucgcccgc cccggcaccg      540

agaccuccga cgucgucugc aagcccugcg cccccggcac cuucuccaac accaccuccu      600

ccaccgacau cugccgcccc caccagaucu gcaacgucgu cgccaucccc ggcaacgccu      660

ccauggacgc cgucugcacc uccaccuccc ccacccgcuc cauggccccc ggcgccgucc      720

accuccccca gcccgucucc acccgcuccc agcacaccca gcccaccccc gagcccucca      780

ccgcccccuc caccuccuuc cuccucccca ugggccccuc cccccccgcc gagggcucca      840

ccggcgacuu cgcccucccc gucggccuca ucgucggcgu caccgcccuc ggccuccuca      900

ucaucggcgu cgucaacugc gucaucauga cccaggucaa gaagaagccc cucugccucc      960

agcgcgaggc caaggucccc caccuccccg ccgacaaggc ccgcggcacc cagggccccg     1020

agcagcagca ccuccucauc accgcccccu ccuccuccuc cuccucccuc gaguccuccg     1080

ccuccgcccu cgaccgccgc gcccccaccc gcaaccagcc ccaggccccc ggcgucgagg     1140

ccuccggcgc cggcgaggcc cgcgccucca ccggcuccuc cgacuccucc cccggcggcc     1200

acggcaccca ggucaacguc accugcaucg ucaacgucug cuccuccucc gaccacuccu     1260

cccagugcuc cucccaggcc uccuccacca ugggcgacac cgacuccucc cccuccgagu     1320

cccccaagga cgagcagguc cccuucucca aggaggagug cgccuuccgc ucccagcucg     1380

agacccccga gacccuccuc ggcuccaccg aggagaagcc ccucccccuc ggcguccccg     1440

acgccggcau gaagcccucc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  6499
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt2)

<400>  6499
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgucaugc gccucuuccc cugcuuccuc cagcuccucg      120

ccggccucgc ccuccccgcc gucccccccc agcagugggc ccucuccgcc ggcaacggcu      180

ccuccgaggu cgaggucguc cccuuccagg aggucugggg ccgcuccuac ugccgcgccc      240

ucgagcgccu cgucgacguc gucuccgagu accccuccga ggucgagcac auguucuccc      300

ccuccugcgu cucccuccuc cgcugcaccg gcugcugcgg cgacgagaac cuccacugcg      360

uccccgucga gaccgccaac gucaccaugc agcuccucaa gauccgcucc ggcgaccgcc      420

ccuccuacgu cgagcucacc uucucccagc acguccgcug cgagugccgc ccccuccgcg      480

agaagaugaa gcccgagcgc cgccgcccca agggccgcgg caagcgccgc cgcgagaagc      540

agcgccccac cgacugccac cucugcggcg acgccguccc ccgccgcuga ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  6500
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt2)

<400>  6500
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgaccgcc agaccgacac cgcccccucc cccuccuacc      120

accuccuccc cggccgccgc cgcaccgucg acgccgccgc cucccgcggc cagggccccg      180

agcccgcccc cggcggcggc gucgagggcg ucggcgcccg cggcgucgcc cucaagcucu      240

ucguccagcu ccucggcugc ucccgcuucg gcggcgccgu cguccgcgcc ggcgaggccg      300

agcccuccgg cgccgcccgc uccgccuccu ccggccgcga ggagccccag cccgaggagg      360

gcgaggagga ggaggagaag gaggaggagc gcggccccca guggcgccuc ggcgcccgca      420

agcccggcuc cuggaccggc gaggccgccg ucugcgccga cuccgccccc gccgcccgcg      480

ccccccaggc ccucgcccgc gccuccggcc gcggcggccg cgucgcccgc cgcggcgccg      540

aggaguccgg ccccccccac ucccccuccc gccgcggcuc cgccucccgc gccggccccg      600

gccgcgccuc cgagaccaug aacuuccucc ucuccugggu ccacuggucc cucgcccucc      660

uccucuaccu ccaccacgcc aagugguccc aggccgcccc cauggccgag ggcggcggcc      720

agaaccacca cgaggucguc aaguucaugg acgucuacca gcgcuccuac ugccacccca      780

ucgagacccu cgucgacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      840

ccuccugcgu cccccucaug cgcugcggcg gcugcugcaa cgacgagggc cucgagugcg      900

uccccaccga ggaguccaac aucaccaugc agaucaugcg caucaagccc caccagggcc      960

agcacaucgg cgagaugucc uuccuccagc acaacaagug cgagugccgc cccaagaagg     1020

accgcgcccg ccaggagaag aaguccgucc gcggcaaggg caagggccag aagcgcaagc     1080

gcaagaaguc ccgcuacaag uccugguccg ucuacgucgg cgcccgcugc ugccucaugc     1140

ccuggucccu ccccggcccc caccccugcg gccccugcuc cgagcgccgc aagcaccucu     1200

ucguccagga cccccagacc ugcaagugcu ccugcaagaa caccgacucc cgcugcaagg     1260

cccgccagcu cgagcucaac gagcgcaccu gccgcugcga caagccccgc cgcugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6501
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt2)

<400>  6501
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc ucuccugggu ccacuggucc cucgcccucc      120

uccucuaccu ccaccacgcc aagugguccc aggccgcccc cauggccgag ggcggcggcc      180

agaaccacca cgaggucguc aaguucaugg acgucuacca gcgcuccuac ugccacccca      240

ucgagacccu cgucgacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      300

ccuccugcgu cccccucaug cgcugcggcg gcugcugcaa cgacgagggc cucgagugcg      360

uccccaccga ggaguccaac aucaccaugc agaucaugcg caucaagccc caccagggcc      420

agcacaucgg cgagaugucc uuccuccagc acaacaagug cgagugccgc cccaagaagg      480

accgcgcccg ccaggagaag aaguccgucc gcggcaaggg caagggccag aagcgcaagc      540

gcaagaaguc ccgcuacaag uccugguccg ucuacgucgg cgcccgcugc ugccucaugc      600

ccuggucccu ccccggcccc caccccugcg gccccugcuc cgagcgccgc aagcaccucu      660

ucguccagga cccccagacc ugcaagugcu ccugcaagaa caccgacucc cgcugcaagg      720

cccgccagcu cgagcucaac gagcgcaccu gccgcugcga caagccccgc cgcugaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  6502
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt2)

<400>  6502
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccccccucc uccgccgccu ccuccucgcc gcccuccucc      120

agcucgcccc cgcccaggcc cccgucuccc agcccgacgc ccccggccac cagcgcaagg      180

ucgucuccug gaucgacguc uacacccgcg ccaccugcca gccccgcgag gucgucgucc      240

cccucaccgu cgagcucaug ggcaccgucg ccaagcagcu cguccccucc ugcgucaccg      300

uccagcgcug cggcggcugc ugccccgacg acggccucga gugcgucccc accggccagc      360

accagguccg caugcagauc cucaugaucc gcuaccccuc cucccagcuc ggcgagaugu      420

cccucgagga gcacucccag ugcgagugcc gccccaagaa gaaggacucc gccgucaagc      480

ccgaccgcgc cgccaccccc caccaccgcc cccagccccg cuccgucccc ggcugggacu      540

ccgcccccgg cgcccccucc cccgccgaca ucacccaccc cacccccgcc cccggccccu      600

ccgcccacgc cgcccccucc accaccuccg cccucacccc cggccccgcc gccgccgccg      660

ccgacgccgc cgccuccucc gucgccaagg gcggcgccug aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  6503
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt2)

<400>  6503
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuccucg gcuucuucuc cgucgccugc ucccuccucg      120

ccgccgcccu ccuccccggc ccccgcgagg cccccgccgc cgccgccgcc uucgaguccg      180

gccucgaccu cuccgacgcc gagcccgacg ccggcgaggc caccgccuac gccuccaagg      240

accucgagga gcagcuccgc uccgucuccu ccgucgacga gcucaugacc guccucuacc      300

ccgaguacug gaagauguac aagugccagc uccgcaaggg cggcuggcag cacaaccgcg      360

agcaggccaa ccucaacucc cgcaccgagg agaccaucaa guucgccgcc gcccacuaca      420

acaccgagau ccucaagucc aucgacaacg aguggcgcaa gacccagugc augccccgcg      480

aggucugcau cgacgucggc aaggaguucg gcgucgccac caacaccuuc uucaagcccc      540

ccugcgucuc cgucuaccgc ugcggcggcu gcugcaacuc cgagggccuc cagugcauga      600

acaccuccac cuccuaccuc uccaagaccc ucuucgagau caccgucccc cucucccagg      660

gccccaagcc cgucaccauc uccuucgcca accacaccuc cugccgcugc auguccaagc      720

ucgacgucua ccgccagguc cacuccauca uccgccgcuc ccuccccgcc acccuccccc      780

agugccaggc cgccaacaag accugcccca ccaacuacau guggaacaac cacaucugcc      840

gcugccucgc ccaggaggac uucauguucu ccuccgacgc cggcgacgac uccaccgacg      900

gcuuccacga caucugcggc cccaacaagg agcucgacga ggagaccugc cagugcgucu      960

gccgcgccgg ccuccgcccc gccuccugcg gcccccacaa ggagcucgac cgcaacuccu     1020

gccagugcgu cugcaagaac aagcucuucc ccucccagug cggcgccaac cgcgaguucg     1080

acgagaacac cugccagugc gucugcaagc gcaccugccc ccgcaaccag ccccucaacc     1140

ccggcaagug cgccugcgag ugcaccgagu ccccccagaa gugccuccuc aagggcaaga     1200

aguuccacca ccagaccugc uccugcuacc gccgccccug caccaaccgc cagaaggccu     1260

gcgagcccgg cuucuccuac uccgaggagg ucugccgcug cguccccucc uacuggaagc     1320

gcccccagau guccugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  6504
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt2)

<400>  6504
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uaccgcgagu gggucgucgu caacgucuuc augaugcucu      120

acguccagcu cguccagggc uccuccaacg agcacggccc cgucaagcgc uccucccagu      180

ccacccucga gcgcuccgag cagcagaucc gcgccgccuc cucccucgag gagcuccucc      240

gcaucaccca cuccgaggac uggaagcucu ggcgcugccg ccuccgccuc aaguccuuca      300

ccuccaugga cucccgcucc gccucccacc gcuccacccg cuucgccgcc accuucuacg      360

acaucgagac ccucaagguc aucgacgagg aguggcagcg cacccagugc uccccccgcg      420

agaccugcgu cgaggucgcc uccgagcucg gcaaguccac caacaccuuc uucaagcccc      480

ccugcgucaa cgucuuccgc ugcggcggcu gcugcaacga ggagucccuc aucugcauga      540

acaccuccac cuccuacauc uccaagcagc ucuucgagau cuccgucccc cucaccuccg      600

uccccgagcu cguccccguc aaggucgcca accacaccgg cugcaagugc cuccccaccg      660

ccccccgcca ccccuacucc aucauccgcc gcuccaucca gauccccgag gaggaccgcu      720

gcucccacuc caagaagcuc ugccccaucg acaugcucug ggacuccaac aagugcaagu      780

gcguccucca ggaggagaac ccccucgccg gcaccgagga ccacucccac cuccaggagc      840

ccgcccucug cggcccccac augauguucg acgaggaccg cugcgagugc gucugcaaga      900

cccccugccc caaggaccuc auccagcacc ccaagaacug cuccugcuuc gagugcaagg      960

agucccucga gaccugcugc cagaagcaca agcucuucca ccccgacacc ugcuccugcg     1020

aggaccgcug ccccuuccac acccgccccu gcgccuccgg caagaccgcc ugcgccaagc     1080

acugccgcuu ccccaaggag aagcgcgccg cccagggccc ccacucccgc aagaaccccu     1140

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  6505
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt3)

<400>  6505
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgaug agaccggcuu cgaacacucc gggcuguggg      120

ugucuguccu cgccggacuu cuguugggug cuugccaggc acaucccauc ccugacucaa      180

guccauuacu gcaauuuggc gggcagguua gacagaggua ccuauauaca gaugacgccc      240

agcaaacuga ggcgcaccuc gaaauucggg aggauggaac ggugggcggu gcugccgacc      300

agagcccgga aucccugcuu cagcugaagg cauugaaacc cgggguaaua cagauccucg      360

gagugaagac cucucgcuuc cugugucaac gaccugaugg cgcccuguac ggcucgcucc      420

auuuugaccc agaggcuugc ucauuccgug aguuacugcu ugaagauggg uauaacgucu      480

accagagcga ggcacacgga uugccccugc aucuaccugg uaauaaaagu ccacacagag      540

accccgcccc uaggggccca gcucgguuuc ucccgcugcc cgggcuuccu ccagcccugc      600

ccgaaccucc aggaauuuug gcgccccagc cgccugaugu gggcuccucu gacccccuca      660

gcaugguugg uccaucccag gggcgcucac cuaguuaugc aagcugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  6506
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt3)

<400>  6506
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc ccccucugcu ccuucuguug uucuggggcg      120

uggucuccca uucuuuccca gccaccuuag agacacagga acaagacguu gaucuggugc      180

agaaguaccu agagaaauau uacaaccuca agaaugacgg gagacaggua gagaaaaggc      240

ggaacucagg accggugguc gaaaagcuga aacagaugca agaauuuuuc ggucuuaagg      300

ugacuggcaa gcccgaugcu gagacgcuga aaguuaugaa gcagccucgc ugcggggugc      360

cagacgucgc acaguuugug uugaccgagg gaaauccccg augggaacag acacaccuca      420

cuuaucguau cgagaacuac accccugauc ugccaagagc cgacguagau caugcgauug      480

aaaaggcuuu ccaacugugg aguaauguua caccccucac cuuuacuaaa gugagcgagg      540

gccaggccga cauaaugauc uccuucguca ggggugauca ccgggacaac ucuccuuuug      600

augggccagg aggcaauuua gcacaugccu uccagccggg ccccgggauu ggaggugacg      660

cucacuuuga ugaggacgaa cgcuggacaa acaauuucag agaguauaac cugcacaggg      720

uggcagccca ugaacuuggc cacucguugg ggcugucaca uagcaccgac aucggagcuc      780

uaauguaccc uaguuauacg uuuuccggcg augugcagcu cgcccaagac gauauugacg      840

guauccaggc gauauacggg cggucucaga auccagucca acccaucgga ccucagacuc      900

caaaagcaug ugauagcaag cugaccuucg acgccauuac aacuauccgc ggcgagguua      960

uguucuuuaa ggaucgauuc uacaugagaa ccaaccccuu uuauccggaa guggagcuua     1020

auuucauuuc cguauuuugg ccucagcugc ccaacggcuu ggaggcugcc uacgaguucg     1080

cagacaggga ugaagugcgg uuuuucaaag ggaauaagua uugggcuguc cagggacaaa     1140

acgugcucca cgguuaccca aaagacaucu auucaaguuu uggcuucccu cguacaguua     1200

agcacauaga ugccgcgcug agcgaagaga acaccgggaa aacguacuuu uucguggcca     1260

auaaguauug gcgcuacgac gaauacaaaa gaucuaugga ccccggauau ccaaagauga     1320

uugcacauga uuuucccggc aucggucaca aggucgacgc uguguucaug aaagaugggu     1380

ucuuuuacuu cuuucauggc acuaggcagu auaaguucga cccuaaaaca aagcggauuu     1440

uaacccugca gaaagccaac uccugguuua auugccgaaa gaacugagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  6507
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt3)

<400>  6507
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc ccccucugcu ccuucuguug uucuggggcg      120

uggucuccca uucuuucguu uuaaccgagg ggaacccaag augggaacag acacaccuga      180

cuuacaggau cgagaauuau acgccggacc uaccccgggc cgauguggac caugcuauug      240

aaaaggcauu ucaacucugg ucaaacguaa ccccucugac auucacuaaa gugagugagg      300

gacaggccga uauaaugauc agcuuugucc gcggugacca ccgagauaau uccccauucg      360

acggccccgg gggaaaccuu gcgcaugcuu uucagccugg cccagguauu gggggagaug      420

cccacuucga cgaagaugag cguuggacca auaacuuuag agaguacaau cugcacaggg      480

uggcagccca ugaauugggc cacucucucg gccugucgca uucaacagac aucggggcuc      540

ugauguaucc cagcuacacc uucaguggag auguucagcu cgcacaagac gauauugacg      600

guauccaggc cauauauggc cggucccaga acccugugca gccaaucggg ccgcaaacuc      660

ccaaggcuug cgacucuaaa uuaacauuug augccauuac cacgauccgc ggagagguca      720

uguucuuuaa ggacagauuc uacaugagga cuaauccuuu cuauccagaa guggagcuga      780

acuuuauuag cguauucugg ccccagcuuc cuaauggcuu ggaggcggca uacgaauuug      840

ccgaucggga cgagguucgc uucuuuaaag guaacaagua cugggcugug caggggcaga      900

auguccugca cggauaucca aaggauaucu acuccucauu cggcuuuccc cgaaccguga      960

aacacauaga cgccgcacua agugaagaga acacaggcaa gacuuauuuc uuuguggcua     1020

auaaauacug gagauaugau gaauacaaga ggagcaugga cccgggguau ccuaaaauga     1080

uugcccauga uuuccccgga aucggucaca aggucgacgc gguuuuuaug aaggauggcu     1140

ucuuuuacuu cuuccauggg acccggcaau acaaauuuga cccaaagaca aaacguauuc     1200

ucacccugca gaaggccaac ucuugguuca acugucgcaa aaauugagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  6508
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt3)

<400>  6508
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaaaaaca uccugaagau ucucauggac agcuacucca      120

aagagucuaa gauacagacc gugagaaggg ucacaucagu uagucuucug gccguguauu      180

ugacuaugaa uacgagcucc uuaguacugg cuaaacccau cgaaaacacc aaugauacau      240

cuauuaagaa cguggagaag cuacggaaug caccuaacga agaaaauucg aaaaaggucg      300

aagacucaaa gaacgauaag guggagcacg uuaaaaauau cgaggaagcc aagguggagc      360

aagucgcgcc agaaguaaag agcaaaagua cucuccgcuc cgcuucuauu gccaacacca      420

auagcgagaa guacgacuuc gaguaucuga acggccuuuc cuacacagaa cugaccaauu      480

ugaucaaaaa cauaaagugg aaucagauca acgggcucuu uaacuauuca acuggaaguc      540

agaaauucuu uggugauaag aaucgagugc aggcaauuau caacgcccug caagagagcg      600

gccguacaua caccgcuaau gacaugaaag ggauugaaac guucacugag guucugagag      660

caggauuuua ucucggcuac uacaacgaug guuuaucuua ucugaaugac aggaacuucc      720

aggauaagug caucccggcc augauagcua uucagaagaa ucccaacuuu aaacuuggga      780

ccgccgugca ggacgaaguc aucacauccu ugggaaagcu gauuggcaau gcgucagcaa      840

acgccgaggu ggugaauaac ugugucccug uucuaaaaca auuccgggag aaucucaacc      900

aguacgcucc agauuaugug aagggcacug ccguaaauga acugaucaaa gggaucgagu      960

uugacuucag cggagcagcu uacgaaaagg augugaagac caugcccugg uaugguaaaa     1020

uugacccuuu uauaaacgag cuuaaggccc ugggcuugua cgggaacauc acaagugcga     1080

ccgaaugggc cucugacguc ggaauuuauu accucuccaa auucggccug uacagcacga     1140

aucgcaacga uaucgugcag ucguuagaga aggcaguuga cauguauaaa uacgguaaga     1200

uagcuuuugu ggccauggag agaauuacuu gggauuauga cgggaucgga ucuaauggca     1260

agaaagucga ucaugacaag uuccuggaug acgcugaaaa acacuaccuc ccaaagacau     1320

auaccuucga uaacggcacu uuuaucauua gggccgggga caaagugucc gaggaaaaga     1380

ucaagcggcu uuacugggca ucacgcgagg uaaaaaguca guuccaucga guugugggaa     1440

augauaaggc ccuggaaguc gguaacgcug acgacguguu gacaaugaaa auuuuuaaua     1500

gccccgagga guauaaguuc aacaccaaua uaaacggcgu cuccacggau aaugggggac     1560

uauacaucga accuagaggc accuuuuaca cauaugagag gacuccacaa cagucuauuu     1620

ucagccugga ggagcucuuu cggcacgagu acacccauua ucugcaggcg cguuaccuug     1680

uggacggucu gugggggcaa ggcccguucu augaaaagaa ccgcuugaca ugguuugaug     1740

agggaacugc agaguucuuu gccggcucaa ccagaacaag ugggguucuc cccaggaagu     1800

ccauccuggg auacuuagcu aaagacaagg uggaucaccg guauagccug aagaaaaccc     1860

uaaauucugg uuacgacgau ucagacugga uguucuacaa cuauggcuuu gccguagcac     1920

acuaccucua ugaaaaggau augccuacuu ucaucaaaau gaauaaggcc auucugaaca     1980

cggacgucaa aaguuacgau gaaauaauca agaaacuuag cgacgaugcu aacaaaaaua     2040

cagaguauca gaaccauauu caggaguugg ccgacaagua ccagggggca ggaaucccac     2100

ugguguccga cgauuaucuc aaagaccacg gcuacaagaa agcgucugaa guuuacucgg     2160

agauuagcaa ggcugccucc cugaccaaua cuucagugac cgcagaaaag agucaauauu     2220

ucaacacauu uacccuucga gguacuuaca caggggagac gucuaaaggc gaguucaagg     2280

auugggacga aaugagcaaa aagcuggaug gaaccuugga gucccucgcc aaaaauucau     2340

ggagcggcua uaagacucug acagcuuacu uuaccaacua ucgcgucaca ucugacaaua     2400

aggugcagua cgauguagug uuccaugggg uuuuaacuga caacgccgau aucuccaaua     2460

acaaagcacc cauagcuaag gucaccggac cuaguacggg ugccgugggc agaaauaucg     2520

aauuuagcgg gaaagacucu aaggaugagg acggaaaaau uguguccuau gauugggacu     2580

ucggcgacgg ugcgaccuca agggggaaga acagugucca cgccuacaaa aaggcuggca     2640

cauacaaugu uacucugaag gugaccgaug acaaaggagc aacagccacu gagagcuuua     2700

ccaucgaaau uaagaacgaa gauacgacaa ccccaaucac uaaagagaug gagcccaaug     2760

acgauauaaa ggaagcuaac ggcccgauug uggagggggu aacagucaaa ggagaccuaa     2820

acggcucgga ugacgccgau accuucuauu uugacgugaa ggaagauggu gacguuacua     2880

ucgagcuccc uuacuccggg ucuagcaauu ucaccuggcu gguguauaag gagggagacg     2940

aucagaacca cauugcauca ggcaucgaca aaaauaacag uaaggucggu acauuuaaau     3000

ccacgaaggg ccggcauuac guguucauau auaaacacga uucugcgagc aauaucuccu     3060

acucacuuaa cauuaagggg uugggaaaug aaaagcugaa agagaaggaa aacaaugaca     3120

gcagugauaa agccaccguu auccccaacu uuaauacuac aaugcagggc ucucuccugg     3180

gggacgauuc ccgcgacuau uacagcuucg aggugaagga agagggagag guaaacauug     3240

aauuagauaa aaaggacgag uucggcguca ccuggacacu gcauccagaa ucgaauauca     3300

acgauagaau aacuuacggu caaguggacg ggaauaaggu gucaaacaaa gucaaacuua     3360

ggccuggaaa auauuacuug cucguuuaua aguacucugg cagugguaau uaugagcugc     3420

gugugaacaa augaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  6509
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt3)

<400>  6509
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuuuucuccu      120

cugccuacuc aauugcuaac acaaauagug agaaauauga cuuugaauac cugaacggcu      180

ugagcuauac ugaguuaacg aaucugauaa agaacaucaa auggaaucag auuaacgggc      240

uauucaauua cuccaccgga ucucaaaagu uuuucgguga uaaaaacaga guccaggcaa      300

ucauuaaugc ccuccaggaa ucgggcagga cauauacugc gaacgacaug aaggggaucg      360

agaccuuuac agaaguucug cgggcuggau ucuaccuugg cuauuacaau gauggucugu      420

cauacuugaa cgaccgcaau uuucaggaua agugcauacc cgccaugauc gcaauucaga      480

aaaacccuaa uuucaagcuc gggaccgccg ugcaagacga gguaaucacu agccugggaa      540

aacugauugg caacgcuagu gcaaacgccg agguggucaa uaacugugug ccaguucuca      600

agcaguuucg agaaaauuua aaccaguaug cuccggauua cgugaaaggc acagccguca      660

augagcugau caaggggaua gaauuugacu uuuccggagc ggcauaugag aaggauguga      720

aaaccaugcc cugguacggu aagauugacc cuuucaucaa cgagcuuaaa gccuugggcc      780

uguaugggaa uauuacgucu gcuacugaau gggccagcga uguaggaauc uacuaucuau      840

ccaaguucgg ccucuacuca accaaccgua augacaucgu ucaaagucug gagaaagcag      900

uggauaugua caaguauggu aaaauugcuu uugucgccau ggaaagaaua acaugggacu      960

acgacgggau cggaagcaac ggcaagaagg uggaucacga caaauuccuu gaugacgcgg     1020

agaagcauua ucugccaaaa acuuacaccu uugauaaugg cacauucauu aucagggccg     1080

gggacaaggu gucugaagag aaaauaaagc gguuguauug ggcaucccgc gaggucaagu     1140

cacaguuuca cagaguugug ggaaacgaua aagcucucga aguagguaau gccgacgaug     1200

ugcugaccau gaagauuuuc aacagccccg aggaauacaa auuuaauacg aacaucaacg     1260

gcgucaguac ugacaauggg ggauuauaua ucgagccuag gggcacauuc uacaccuacg     1320

aacggacucc acagcagucu auuuucuccc uggaggagcu guuccgccau gaauauacac     1380

acuaccuuca agcucgauau cugguggaug guuugugggg gcagggcccc uuuuacgaga     1440

agaacagacu aaccugguuc gacgaaggaa cggccgaguu uuucgcaggc agcaccagga     1500

caucgggggu ucugccucgg aaaucuaucc ucggauaucu ggccaaggac aagguggauc     1560

aucguuacuc ccuuaaaaag acucucaauu cagguuauga cgauagugac uggauguucu     1620

acaacuacgg cuuugcuguc gcgcacuauu uguacgaaaa agauaugcca accuucauua     1680

agaugaauaa agcaauacuc aacacagacg uaaagagcua ugaugagauc auuaagaaac     1740

uguccgacga ugccaauaag aacacugagu accagaauca cauccaagaa uuagcugaca     1800

aauaucaggg ggccggaauc ccgcuggugu cugaugacua ccuaaaggau cauggcuaua     1860

aaaaggcaag cgagguuuac ucagaaauua guaaagccgc uucccucacc aacacaagcg     1920

ugaccgccga gaagucucag uacuuuaaua cuuucacgcu gcgcgguaca uauaccgggg     1980

agacuucaaa gggcgaauuu aaagacuggg acgagaugag uaagaaacuu gauggaaccu     2040

uggaaagccu ggcaaagaac uccuggucug gcuacaaaac acucaccgcg uauuucacua     2100

auuacagagu cacaucggac aacaaggugc aguaugaugu cguguuucac gggguucuga     2160

cggacaaugc ugauauaagc aacaacaagg cccccaucgc aaaagugacc ggaccuucca     2220

cuggugccgu aggcaggaau auugaguucu cagggaagga caguaaagau gaagacggaa     2280

agaucgucuc uuacgauugg gacuuuggcg auggugcuac aagccggggg aaaaacuccg     2340

ugcaugccua uaagaaggca ggcaccuaca auguuacacu uaaagugacu gacgauaagg     2400

gagcuaccgc cacggaguca uucaccauug agaucaaaaa cgaagacaca acuaccccaa     2460

uaacaaagga gauggaaccc aaugacgaua ucaaagaggc gaacggcccu auugucgaag     2520

gggugacugu aaagggagac cugaauggca gcgaugacgc cgauaccuuu uacuucgacg     2580

ugaaggagga uggugacguu acgaucgagu ugccauauuc uggguccagu aacuuuacau     2640

ggcucgucua caaagaagga gaugaccaaa aucacauugc uagcggcauc gauaagaaca     2700

auucuaaagu ggguaccuuc aaguccacua aaggccgaca cuauguguuc auauacaagc     2760

augacucagc aaguaacauu agcuauucgc ugaauaucaa aggguuagga aacgagaagc     2820

ugaaggaaaa agagaauaac gacuccucug auaaggccac agucauuccc aacuuuaaua     2880

ccacuaugca gggcagccua cucggggacg auucacgcga cuacuauagu uucgaaguua     2940

aagaggaggg agaagugaac aucgagcugg auaagaaaga cgaauuuggc gugaccugga     3000

cacuucaccc ggaguccaau auaaacgaua gaaucacgua cggucaggua gacgggaaua     3060

aggucucuaa caaggugaaa uugaggccug gaaaguacua ucugcucguu uacaaauaua     3120

gcggcuccgg uaauuacgag cugcggguga acaagugagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  6510
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt3)

<400>  6510
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuuuucuccu      120

cugccuacuc aaugaaaaag aacauucuga aaauauugau ggacaguuau agcaaggagu      180

ccaaaaucca gacagucaga aggguuacuu cugugucguu acuggcugua uaccuaacga      240

ugaauaccuc aagccucgug cuggcaaagc ccauugaaaa cacaaaugau acuagcauca      300

agaacgucga gaaacuucgg aaugccccua acgaagaaaa uuccaagaaa guggaagacu      360

cuaagaacga uaaaguugag cacgugaaga auauugagga agcgaagguc gagcaagugg      420

cuccagaagu aaaaagcaag uccacccugc gcucagccag ucgacguaga aggaaacgga      480

ucgcaaacac aaauagcgag aaguaugacu uugaguacuu gaacggccuc ucuuauaccg      540

aacugacuaa ucugaucaaa aacauaaagu ggaaucagau uaacggacuc uucaacuacu      600

ccacaggauc acagaaauuu uucggugaua agaaucgcgu ucaggccauc auuaacgcuu      660

uacaagagag cggcagaacc uauacggcaa augacaugaa ggggaucgaa acuuuuaccg      720

aggugcugag ggccggauuc uaccuuggcu acuauaacga ugguuugagu uaccugaaug      780

accggaacuu ucaggauaaa ugcauaccgg cuaugauugc cauccagaag aaucccaacu      840

ucaaacuagg gacagcgguc caggacgaag ugauuacuuc ucucggaaag cugaucggca      900

augcauccgc caacgcugag guggucaaua acuguguucc ugugcuuaaa caauuucgcg      960

agaaucugaa ccaguaugcc ccagauuacg uaaagggcac cgcagugaau gaauugauca     1020

aggggauuga guucgacuuu agcggagcug ccuaugaaaa agaugucaag acaaugcccu     1080

gguacgguaa aauagacccu uucaucaacg agcucaaggc gcugggcuua uaugggaaca     1140

uuaccucggc cacggaaugg gcaucugacg ugggaaucua cuaccugucc aaauucggcc     1200

ucuauucaac uaaucgaaac gauauaguuc agagucuuga gaaggcugug gacauguaca     1260

aguaugguaa aauugccuuu gucgcuaugg agagaaucac augggauuac gacgggaucg     1320

gaagcaaugg caagaaagug gaucaugaca aguuccugga ugacgccgaa aaacacuauu     1380

ugccaaagac cuacacuuuu gauaacggca cauucauuau cagggcaggg gacaagguau     1440

ccgaggagaa aauuaagcgg cuauauuggg ccucucguga gguuaaaagc caguuucauc     1500

gcguggucgg aaaugauaag gcucuggaag uggguaacgc ggacgacguc cucaccauga     1560

aaauauucaa uucacccgag gaguacaagu uuaacacgaa uaucaacggc gugaguaccg     1620

auaauggggg acuguacauu gaaccuagag gcacauucua uacuuacgag aggaccccac     1680

aacaguccau cuuuagccuu gaggaacugu uccggcacga guauacacau uacuugcagg     1740

cacgauaucu cguugacggu cugugggggc aaggcccguu uuacgagaaa aaccgcuuaa     1800

cuugguucga ugaaggaacc gccgaauuuu ucgcuggcuc uacaagaacc ucaggggugc     1860

ugcccaggaa gaguauccua ggauaucucg ccaaggacaa aguagaucac cgguacagcc     1920

ugaagaaaac ucuuaauucc gguuacgacg auucugacug gauguucuau aacuacggcu     1980

uugcagucgc ccacuauuug uacgagaagg auaugccuac guucauuaaa augaauaagg     2040

cuauacugaa cacagacgug aagucguaug augaaaucau uaaaaagcuc agcgacgaug     2100

ccaacaaaaa uaccgaguac cagaaccaua uccaggagcu ggcagacaag uaucaggggg     2160

cggggauucc acuuguuucc gacgauuacc ugaaagacca cggcuacaag aaggcuucag     2220

aaguguauag ugagaucucu aaagccgcaa guuugacuaa uaccuccguc acagccgaaa     2280

agucacaaua cuuuaacacc uucacucucc gcgguacaua uacgggggag accagcaaag     2340

gcgaauuuaa ggauugggac gagaugucua aaaagcugga uggaacuuua gagucccugg     2400

cuaagaauag uuggagcggc uacaaaacac uaaccgccua uuucacaaac uacagaguga     2460

cuucugacaa uaagguacag uaugaugugg uuuuucaugg gguccucacc gacaacgcag     2520

auauauccaa uaacaaagcu cccaucgcca aggugacggg accuucaacc ggugcggugg     2580

gcaggaauau ugaguucagu gggaaagaca gcaaggauga agacggaaaa aucgucucgu     2640

acgauuggga cuuuggcgac ggugccacau cccgugggaa gaacucuguu cacgcuuaca     2700

agaaagcagg cacuuauaau gugacccuga aggugacaga ugacaaagga gccacugcua     2760

ccgagagcuu cacgauugaa aucaagaacg aagauacaac cacuccaaua acaaaagaga     2820

uggagcccaa ugacgauauu aaggaagcca acggcccgau cguagagggg gucaccguga     2880

agggagaccu uaacggcuca gaugacgcag auacuuuuua cuucgacguu aaagaagaug     2940

gugacgugac cauugaguug ccuuauagug gguccucuaa uuuuacaugg cuggucuaca     3000

aggagggaga cgaucagaac cacaucgcga gcggcauaga caaaaauaac uccaaggugg     3060

guacguucaa aucaaccaag ggccggcauu auguuuucau cuacaagcac gauagcgcca     3120

guaauauuuc uuauucccuc aacaucaaag ggcugggaaa ugaaaaguua aaagagaagg     3180

aaaacaauga cagcucggau aaagcuacug ugauucccaa cuuuaauaca accaugcagg     3240

gcucacugcu uggggacgau ucucgagacu acuacaguuu cgagguaaag gaagagggag     3300

aggucaacau cgaauuggau aagaaagacg aguuuggcgu gacauggacu cuccauccag     3360

aauccaauau aaacgauaga auuaccuaug gucaagugga cgggaauaag gucagcaaca     3420

aaguuaagcu gaggccugga aaauacuauc uacuggugua caaguauucu ggcagcggua     3480

auuacgagcu ccgcguaaac aagugaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  6511
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt3)

<400>  6511
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuga agaucauucu caauagaggc aaaaccauga      120

agaggaaaug ccuuagcaag cggcugaugu uggccauaac aauggcuacu aucuuuacgg      180

ugaacuccac cuuacccauu uacgcagccg ucgacaaaaa uaacgcgaca gcugccguuc      240

agaaugaguc uaagcgcuau acugugucau accugaagac ccuaaacuau uacgaucucg      300

uagaccugcu ugugaaaaca gaaaucgaga aucugccuga uuuguuccaa uauaguagcg      360

acgcaaagga auuuuacggg aacaaaaccc gaauguccuu cauuauggau gagaucggac      420

guagagcccc acaguauacu gaaauagacc acaaggguau cccgacacuc gucgaggugg      480

uuagggcugg cuuuuaccug ggguuccaua auaaagagcu gaacgaaauu aauaagcggu      540

cuuuuaagga gcgcgugauc cccucgauuc ucgcaaucca gaaaaacccu aauuucaagu      600

uaggaaccga aguccaggau aaaauagugu cagccacggg ccugcuugcu gguaacgaga      660

cugccccacc cgagguaguu aauaacuuua ccccuauuuu gcaagacugu aucaagaaca      720

uugauagaua cgcgcuggac gaucuaaaaa gcaaggcacu cuucaaugug cuggccgcuc      780

caacauauga caucacugaa uaccuuaggg ccaccaaaga gaagcccgaa aacacaccuu      840

gguaugggaa gaucgaugga uuuauuaaug agcugaaaaa guuggcacuc uacggcaaaa      900

uaaacgacaa uaacaguugg aucauugaca auggcaucua ucacauagcu ccacugggga      960

aguuacauuc caacaauaaa auuggaaucg aaacccugac ggaggucaug aagguguacc     1020

cguaucucuc uaugcagcac cuucagagcg ccgaucagau caagcggcau uacgacucca     1080

aagaugcgga ggguaacaag auuccccugg acaaauucaa gaaagaaggc aaggagaagu     1140

acugcccuaa aacuuauaca uuugaugacg ggaaggugau cauuaaagcc ggagcacgcg     1200

ucgaagagga aaagguuaaa cgauuguacu gggcuucaaa ggaggugaau agucaauucu     1260

ucagaguaua uggcauagau aagccacuag aggaagguaa ccccgacgau auccugacca     1320

uggugauuua caauagcccu gaggaauaua aacucaacuc uguccuguac ggguaugaca     1380

cuaauaacgg aggcauguac aucgagccag aaggcacauu uuucaccuac gagagggagg     1440

cccaggaauc cacguauacc cuugaggaac uguuucggca cgaguacaca cacuauuugc     1500

aggggcguua cgcugugccc ggacaguggg gucgcacuaa gcucuaugau aacgacagac     1560

ugaccuggua cgaggaaggc ggggccgagu uauucgcagg aucaacaagg acuagcggca     1620

uccugccgcg gaaaaguauu guuucuaaua uacauaacac cacacgaaau aaccgcuaua     1680

agcuauccga caccgugcac agcaaauacg gugccucguu ugaguucuac aauuaugcuu     1740

guauguuuau ggauuacaug uauaacaagg acauggggau ccucaauaaa cugaacgauc     1800

uugcgaagaa uaacgacguc gauggcuacg acaauuauau uagagauuug ucuuccaacu     1860

acgcacugaa ugacaaguau caagaucaua ugcaggaaag gaucgacaac uacgaaaauc     1920

ucacugugcc uuucguagcc gaugacuacc ugguucggca cgcuuauaaa aaccccaacg     1980

agauuuacuc agagaucagu gaaguggcca aacuuaagga ugcaaagagc gaggucaaaa     2040

agucccagua uuuuucuacg uucacacugc gcggaagcua caccggcggg gccucaaagg     2100

gaaaauugga agaccaaaag gcuaugaaua aauuuauaga cgauagucuc aagaaacugg     2160

acacuuauuc cuggagcggu uacaagaccu uaacagccua uuucaccaac uacaaggugg     2220

auucuucaaa uagagucacu uacgacgugg uuuuucacgg cuaucugcca aacgaggggg     2280

auaguaaaaa uagccuaccu uacggaaaga ucaacggcac auauaaaggu acggaaaagg     2340

agaaaauuaa guucuccucu gaggggucgu ucgaccccga uggcaagauc gugagcuacg     2400

aaugggacuu uggagauggc aauaaaucca acgaggaaaa uccagagcau ucauaugaca     2460

agguagggac cuacacuguc aaacucaagg ugacagauga caaaggagaa aguucuguua     2520

gcaccacaac ugcagagauu aaggaucugu ccgagaacaa acuucccgug aucuauaugc     2580

acgucccuaa gucaggugcg uugaaucaga aggugguauu cuacggcaaa gggaccuacg     2640

acccagacgg aagcauagcu ggcuaucagu gggauuuugg ugacgggucu gauuucucca     2700

gugaacagaa cccgagccau guguacacga agaaaggcga guauaccguu acacugaggg     2760

ucauggacuc uuccggacaa augucagaaa agacuaugaa aauuaagauc accgaucccg     2820

uguacccuau uggcacagag aaggagccaa auaacaguaa agaaacugcc agcgggccca     2880

ucgugccugg aauaccaguc ucgggcacca ucgagaauac guccgaccag gauuauuuuu     2940

acuucgacgu uauuacaccc ggugaaguga agaucgauau uaacaaacuc ggguauggag     3000

gcgcaaccug ggugguauac gacgagaaca auaacgccgu cucuuacgcu acugaugacg     3060

gucagaaucu gagcggcaag uuuaaagccg acaagccggg gcguuauuac auccacuuau     3120

auauguucaa cggaucauac augccuuauc ggauaaauau ugaaggcagu guggggcgau     3180

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  6512
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt3)

<400>  6512
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagagaaaau gccugagcaa gaggcucaug cuugccauca      120

ccauggcuac aauuuucacu gugaacucca cgcugcccau auacgcagcc gucgacaaaa      180

auaacgcgac cgcugccguu cagaaugagu cuaagcggua uacaguguca uacuugaaaa      240

cuuuaaacua uuacgaucug guagaccuac ucgugaagac cgaaaucgag aaucugccug      300

aucuuuuuca auauaguagc gacgcaaagg aguucuacgg caacaaaaca cgcauguccu      360

uuauuaugga ugaaaucggg cgacgugccc cacaguauac cgaaauugac cacaagggaa      420

ucccgacucu ggucgaggug guuagagcug guuucuacuu gggcuuucau aauaaagagc      480

ucaacgaaau aaauaagagg ucuuucaaag agcgggugau ccccucgauu cuggcaaucc      540

agaagaaccc uaauuuuaag cuggggacag aaguccagga uaaaauugug ucagccaccg      600

gacucuuagc uggcaacgag acggccccac ccgagguagu uaauaacuuc acuccuaucc      660

ugcaagacug uauaaagaau auugaucgcu acgcgcuuga cgauuugaaa agcaaggcac      720

uguuuaacgu gcuagccgcu ccaaccuaug acaucacaga auaccucaga gccacuaaag      780

agaagcccga aaacaccccu ugguauggua aaauugaugg guucaucaau gagcugaaga      840

agcuggcacu guacggaaaa aucaacgaca auaacaguug gauuauagac aauggcaucu      900

aucacauugc uccauugggc aagcuccauu ccaacaauaa aaucgggaua gaaacacuga      960

ccgaggucau gaagguguac ccguauuuau cuaugcagca ccuucagagc gccgaucaga     1020

uuaaaaggca uuacgacucc aaggaugcgg agggaaacaa gaucccccuc gacaaauuua     1080

agaaagaagg uaaggagaaa uacugcccua agacguauac uuucgaugac ggcaagguga     1140

ucauuaaagc cggggcacgg gucgaagagg aaaagguuaa acgccuuuac ugggcuucaa     1200

aggaggugaa uagucaauuu uuccgaguau auggaaucga uaaaccacug gaggaaggca     1260

accccgacga uauuuugaca auggugauau acaauagccc ugaggaauau aagcuaaacu     1320

cuguccugua cgguuaugac accaauaacg ggggaaugua caucgagcca gaaggcacuu     1380

ucuuuacaua cgagagagag gcccaggaau ccaccuauac gcucgaggaa cuguucaggc     1440

acgaguacac ccacuaucuu cagggccggu acgcugugcc cgggcagugg ggacguacaa     1500

agcuguauga uaaugaccgc uugacuuggu acgaggaagg uggcgccgag cucuuugcag     1560

ggucaaccag aacaagcggc auucugccga ggaaaaguau cguuucuaac auccauaaca     1620

cuacccggaa uaaccgauau aaguuauccg acacagugca cagcaaauac ggagccucgu     1680

ucgaauuuua caauuaugcu uguauguuca uggauuacau guauaacaag gacaugggua     1740

uucugaauaa acuaaacgau cucgcgaaga auaacgacgu cgauggguac gacaauuaua     1800

uacgcgaucu gucuuccaac uacgcacuua augacaaaua ucaagaucau augcaggaga     1860

gaaucgacaa cuacgaaaau uugaccgugc cuuuuguagc cgaugacuac cugguuaggc     1920

acgcuuauaa gaaccccaau gagauuuacu cagagaucag ugaaguggcc aagcucaaag     1980

augcaaagag cgaggucaaa aagucccagu auuucucuac uuuuacgcug cggggcagcu     2040

acacaggagg cgccucaaaa gggaaacuug aagaccaaaa ggcuaugaac aaguucauug     2100

acgauagucu gaagaaauug gacaccuauu ccuggagcgg auacaagacu cucaccgccu     2160

auuuuacaaa cuacaaagug gauucuucaa aucgcgucac cuacgacgug guuuuccacg     2220

guuaucugcc aaacgagggc gauaguaaga auagcuuacc uuacgggaag aucaacggaa     2280

cuuauaaagg cacagaaaag gagaaaauaa aguuuuccuc ugaggguucg uucgaccccg     2340

augggaaaau cgugagcuac gaaugggacu ucggcgaugg aaauaagucc aacgaggaaa     2400

auccagagca uucauaugac aagguaggca cguacaccgu caaacugaag gugacugaug     2460

acaaagggga aaguucuguu agcacaacca cagcagagau uaaggaucua uccgagaaca     2520

aacuccccgu gaucuauaug cacgucccua agucaggagc gcugaaucag aaagugguau     2580

uuuacgguaa gggcacuuac gacccagacg ggagcauugc uggauaucag ugggauuucg     2640

gcgacgguuc ugauuuuucc agugaacaga acccgagcca uguguacacc aagaaagggg     2700

aguauacggu uacccuuaga gucauggacu cuuccggcca aaugucagaa aagacaauga     2760

aaaucaagau aacugauccc guguacccua uuggaaccga gaaagagcca aauaacagua     2820

aggaaacagc cagcggcccc aucgugccug ggauuccagu cucgggaacu aucgagaaua     2880

ccuccgacca ggauuauuuc uacuuugacg uuauaacgcc cggcgaagug aagaucgaua     2940

uuaacaaauu ggguuauggg ggagcaacau gggugguaua cgacgagaau aacaacgccg     3000

ucucuuacgc uaccgaugac ggccagaauc ugagcgguaa guucaaagcc gacaagccgg     3060

gcagguauua cauccaccuc uauauguuua acgggucaua caugccuuau cguauuaaua     3120

ucgaaggaag ugugggccgg ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  6513
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt3)

<400>  6513
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuuuucuccu      120

cugccuacuc aguccagaac gagaguaaaa gauauacagu uagcuaccug aagacuuuga      180

auuauuacga cuuaguggau cugcuaguaa aaacggaaau ugagaaccuc cccgaccugu      240

uucaauauuc cucugaugcu aaggaguucu acggcaauaa aaccaggaug ucguuuauaa      300

uggacgaaau cggccggcgc gcaccucagu auacagaaau ugaucacaag ggaaucccaa      360

cucuugugga ggucgugcga gccgguuucu accugggcuu ucauaacaag gaguugaaug      420

aaauuaacaa acguucauuc aaggagagag uuaucccgag cauacucgcg auccagaaaa      480

aucccaacuu uaagcugggg accgaagugc aggacaaaau ugucagugcu acaggacugc      540

ucgccggcaa ugagaccgca ccuccagagg ugguaaacaa uuucacuccc aucuuacaag      600

auugcauuaa gaacaucgac agguacgccc uggaugaccu uaaguccaag gcuuuguuua      660

auguucuggc agccccuaca uaugauauaa ccgaauaccu acgggcuacg aaggagaaac      720

cagaaaacac ucccugguau gguaagauug acggguucau caaugagcuc aaaaagcugg      780

cccuuuacgg aaaaauuaac gauaacaauu cuuggaucau cgacaacggc auuuaucaca      840

uagcgccucu gggcaaguug cauagcaaua acaagaucgg gauugaaacc cucacagagg      900

ugaugaaagu cuacccauau cuguccaugc agcacuuaca gucagcagac cagaucaagc      960

gccauuacga uaguaaagac gccgagggaa auaagauacc gcuggauaaa uuuaagaagg     1020

aagguaaaga gaaguacugu cccaaaacuu auaccuucga cgauggcaag gugauuauca     1080

aagcuggggc cagaguggaa gaggaaaagg ucaagaggcu cuacugggca agcaaagagg     1140

uuaacucuca auucuuucgg guguauggaa ucgacaagcc ucuugaggaa ggcaauccag     1200

augacauucu gacaauggua aucuacaacu cccccgagga auauaaacua aauucagugu     1260

uguacgguua ugauaccaac aaugggggaa uguacauuga gccugaaggc acguucuuua     1320

cuuacgagcg cgaggcucag gaaagcacau auacccugga ggaacucuuc cgacacgagu     1380

acacucacua ucugcagggc agauacgccg ucccagggca guggggaagg acaaaacuuu     1440

augacaacga ucggcugacc ugguacgagg aagguggcgc ggaguuguuu gccgggagua     1500

cgcguaccuc uggaauacuc ccccgcaaau ccaucgugag caauauucau aacacaacua     1560

gaaauaacag guauaagcug ucggacaccg uucacucuaa guacggcgca uccuucgaau     1620

uuuacaacua ugcuugcaug uucauggacu acauguauaa uaaagauaug gguaucuuaa     1680

acaagcugaa ugaccuagcc aaaaacaaug auguggacgg guacgauaac uauauccggg     1740

accucucaag uaauuacgcu cugaacgaua aguaucaaga ccauaugcag gagcgaauug     1800

auaauuacga aaaccuuaca gucccguuug uggccgacga uuacuuggua cgccacgcau     1860

auaaaaaucc uaacgagaua uacagcgaga ucuccgaagu ugccaagcug aaagacgcua     1920

agucugaggu gaagaaaagc caguauuucu caacuuuuac ccucagaggc aguuacacag     1980

gaggcgcguc caaggggaaa cuggaagauc aaaaggcaau gaauaaauuc auugacgaca     2040

gccuuaagaa gcuggauacc uauucuuggu caggauacaa aacuuugacg gccuauuuua     2100

caaacuacaa ggucgacagu agcaauaggg ugaccuacga ugucguguuc cacgguuauc     2160

uccccaacga gggcgacucc aaaaacucuc ugccauacgg gaagaucaau ggaacuuaua     2220

aaggcaccga aaaggagaag auuaaauucu cgagcgaggg uuccuuugau ccugacggga     2280

agaucguuuc auacgaaugg gauuucggcg acggaaacaa aaguaaugag gaaaaccccg     2340

agcauucuua ugauaaggug ggcacauaca ccguaaaauu aaaggucacu gacgauaagg     2400

gggaaagcuc cgugucaaca acgaccgcug agauaaaaga ccugagcgag aauaagcuac     2460

caguuaucua uaugcacgug cccaaaucug gagcccucaa ccagaagguc guguuuuacg     2520

guaaaggcac uuacgauccu gacgggucca uugcaggaua ucagugggac uucggcgaug     2580

guagugacuu uagcucugaa cagaauccau cccauguaua cacaaagaaa ggggaguaua     2640

ccgugacacu gcggguuaug gauucaagug gccaaaugag cgaaaagacu augaagauca     2700

aaauuaccga cccggucuac cccaucggaa cggagaagga gccuaacaau ucgaaagaaa     2760

ccgccuccgg cccaauagug cccgggauuc cugugucugg aacaaucgag aacacuagcg     2820

aucaggacua uuucuacuuu gaugucauua ccccaggcga aguuaagauc gacauaaaua     2880

aacuugguua ugggggagcu acaugggugg uguacgauga gaacaauaac gccguaucau     2940

acgcaacuga cgauggccag aauuugagug guaaguucaa ggcggacaaa cccggccgcu     3000

auuacaucca ccuguauaug uuuaacgggu ccuacaugcc guauagaauu aacaucgaag     3060

gaucugucgg gaggugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6514
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt3)

<400>  6514
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuuuucuccu      120

cugccuacuc aaugaaaaga aagugccuga guaaaagguu gauguuagcu auuacaaugg      180

caacuauauu uacggucaac agcacccugc ccaucuaugc cgcgguugac aagaauaacg      240

cuacagccgc acggcgccga cguaaaagag ugcagaauga guccaagagg uacacuguau      300

cuuaucuaaa gacccucaac uacuaugauc ugguggaccu ucuggucaaa acagaaauug      360

agaauuugcc ugaucucuuc caauacucgu cagacgccaa ggaauuuuau ggcaacaaaa      420

cccggaugag cuucaucaug gaugagauug ggcgcagagc uccacaguac acugaaaucg      480

accacaaggg aauaccgaca cugguggagg uugugagggc agguuuuuac cugggcuucc      540

auaauaaaga gcucaacgaa aucaauaagc ggaguuuuaa ggagcgcguc auucccucca      600

ucuuagccau ucagaaaaac ccuaauuuca agcuggggac cgaagugcag gauaaaaucg      660

uaucugcuac gggacuuuug gccggcaacg agacugcgcc acccgagguu gugaauaacu      720

uuaccccuau acugcaagac uguauuaaga auaucgaucg auaugcacua gacgaucuca      780

aaagcaaggc ccuguucaac guccuugcug ccccaacaua cgacauuacu gaauaucuga      840

gagcaaccaa agagaagccc gaaaacacac cuugguacgg uaagaucgau ggguuuauca      900

augaguugaa aaagcucgcu cuguauggaa aaauuaacga caauaacucc uggauaaucg      960

acaauggcau uuaccacauc gccccauuag gcaagcugca uucaaacaau aaaauaggga     1020

uugaaacccu cacggaggug augaaggugu auccguaccu uaguaugcag caucugcaga     1080

gcgcggauca gaucaagagg cacuacgacu cuaaagaugc cgagggaaac aagauccccu     1140

uggacaaauu caagaaagaa gguaaggaga aguauugccc uaaaacuuac acauucgaug     1200

acggcaaggu cauuaucaaa gcaggggcuc ggguugaaga ggaaaaggug aaacgucuau     1260

auugggccuc caaggaggua aauucacaau uuuuccgcgu guacggaauu gauaagccac     1320

uggaggaagg caaccccgac gauauacuca ccauggucau cuauaauagc ccugaggaau     1380

acaaacugaa cagugugcuu uaugguuacg acacuaauaa cgggggaaug uacauugagc     1440

cagaaggcac auuuuucacc uaugagagag aggcucagga aucuacguac acccuggagg     1500

aauuguuuag gcacgaguau acacacuacc uccagggccg guaugccguu cccgggcagu     1560

ggggacgaac uaagcuguac gauaaugacc gcuuaaccug guaugaggaa gguggcgcag     1620

agcuguucgc cggguccaca agaacuagcg gaauccuacc gaggaaaucg aucgugucua     1680

acauucauaa caccacacgg aauaaccgcu acaagcucuc cgacaccguc cacucaaaau     1740

acggcgcuag uuuugaguuc uauaauuacg cguguauguu uauggauuau auguacaaca     1800

aggacauggg uauacugaau aaacuuaacg auuuggcaaa gaauaacgac guggaugggu     1860

augacaauua caucagagau cugagcucca acuaugcccu caaugacaag uaccaagauc     1920

auaugcagga aaggauugac aacuacgaaa aucugacugu accuuucguu gcugaugacu     1980

aucuugugcg ucacgccuac aaaaacccca augagaucua uucugagauu agcgaagucg     2040

caaagcugaa agaugccaag ucagagguga aaaagaguca guacuuuucc acguucacau     2100

ugcggggcag cuauaccgga ggcgcuucua aggggaaacu cgaagaccaa aaggccauga     2160

acaaauuuau cgacgauuca cugaagaaau uagacacuua caguuggagc ggauauaaga     2220

cccugacagc auacuucacc aacuacaagg ucgauuccuc uaaucgagug acuuaugacg     2280

uuguguucca cgguuaccua ccaaacgagg gcgauucgaa aaauagccuc ccuuauggga     2340

agauaaacgg aacauacaaa ggcacggaaa aggagaaaau caaguuuucc ucagagggua     2400

guuucgaccc cgaugggaag auuguaucuu augaauggga cuuuggcgau ggaaauaaaa     2460

gcaacgagga aaauccagag cauuccuacg acaaggucgg caccuauacu gugaaacuga     2520

agguuacaga ugacaaaggg gaaucaagcg ugucuaccac aacugcggag aucaaggauc     2580

uuuccgagaa caaauugccc gucauuuaca ugcacgugcc uaagagugga gcucugaauc     2640

agaagguagu guucuacggu aaaggcaccu augacccaga cgggagcauc gccggauacc     2700

agugggauuu uggcgacggu ucugauuucu ccucagaaca gaacccgagu cauguuuaua     2760

cgaagaaagg ggaguacacc gucacacuca gagugaugga cagcucgggc caaauguccg     2820

aaaagacuau gaaaauaaag auuaccgauc ccguguaucc uaucggaaca gagaaggagc     2880

caaauaacuc uaaagaaacu gcaagcggcc ccauuguccc ugggauccca guuucaggaa     2940

ccauagagaa uacgagugac caggauuacu uuuauuucga cgugaucaca cccggcgaag     3000

ugaagauuga uaucaacaaa cuggguuacg ggggagccac cuggguaguc uacgacgaga     3060

auaacaacgc uguguccuau gccacugaug acggccagaa uuuaucuggu aaguuuaaag     3120

cagacaagcc gggcagguac uauauucacc uguacauguu caacgggagc uauaugccuu     3180

accgcaucaa uauagaagga uccguuggcc ggugaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  6515
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt3)

<400>  6515
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccuu ggggcugcau      120

uugccaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc agcuaugagg      180

uguugacacc uuuaaagugg uaccagucca uaagaccacc cuauccuucu uacggcuaug      240

aaccaauggg aggguggcug caccaucaaa ucauucccgu ccuaucacag cagcacccuc      300

caacucauac gcuccagccg caccaccaua uccccguugu gccugcgcaa cagccaguaa      360

uuccccagca gccuaugaug ccagugcccg gccaacacag uaugaccccg auccagcauc      420

accagccuaa ucugcccccu ccagcucagc aacccuacca gccacagccc guccaaccuc      480

agccacacca gccgaugcag ccccaaccuc cagugcaucc caugcagccu cuuccacccc      540

agccgccucu gccacccaug uuuccuaugc agcccuugcc accuaugcuc cccgaccuga      600

cacuggaggc cuggccaagc acugauaaaa ccaagaggga agagguugac ugaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  6516
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt3)

<400>  6516
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccaguc cauuagacca cccuauccuu      180

cuuacggaua ugaaccaaug gguggcuggu gaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  6517
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt3)

<400>  6517
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccaguc cauuagacca cccccuaugc      180

ugccagacuu gacauuagaa gccuggcccu cuacugauaa aacgaagagg gaggaagucg      240

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  6518
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt3)

<400>  6518
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cuucugagcg      120

gcgcauuggc cuuaacacag acuugggcga ugccucugcc accgcacccc gggcauccug      180

gauacaucaa cuucuccuau gagguucuaa cgccacucaa gugguaccaa ucuauuaggc      240

ccccuuaucc aucauacggu uaugaaccca ugggcgggug gugaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  6519
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt3)

<400>  6519
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cuucugagcg      120

gcgcauuggc cuuaacacag acuugggcga ugccucugcc accgcacccc gggcauccug      180

gauacaucaa cuucuccuau gagguucuaa cgccacucaa gugguaccaa ucuauuaggc      240

ccccuccaau gcugcccgac cuuacccugg aggcuuggcc uucaacagau aaaacuaagc      300

gggaagaagu ggacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  6520
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt3)

<400>  6520
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccucgug ggggcugcau      120

uugccaugcc ccuuccucca cacccgggac aucccgguua cauuaacuuc agcuaugagg      180

uccugacacc uuugaagugg uaccagucca ugauaagacc acccuauucu ucauacggcu      240

augaaccuau gggagggugg uuacaccauc aaaucauucc aguugugagu cagcagcacc      300

cccugacuca uacgcuacag agccaccacc auaucccugu agugccagcg caacagccga      360

ggguccggca gcaggcucuc augcccgugc cuggccaaca guccaugacc ccaacacagc      420

accaucagcc caaucugccu cuuccagccc aacagcccuu ucagccgcaa ccuguucagc      480

cccagccaca ccagccuaug caaccccagc cacccgugca gccuaugcag ccacuguugc      540

cgcaaccccc ucucccaccc auguucccuc ugcgcccacu gcccccgauu cucccugacu      600

uacaccugga ggcauggcca gccacugaua aaaccaagca ggaagagguc gacugaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  6521
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt3)

<400>  6521
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccaguc caugauuaga ccacccuauu      180

cuucauacgg auaugaaccu auggguggcu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6522
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt3)

<400>  6522
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccaguc caugauuaga ccacccccua      180

uacugccaga cuugcacuua gaagccuggc ccgcuacaga uaaaacuaag caagaggaag      240

ucgacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6523
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt3)

<400>  6523
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cuucugagcg      120

gcgcauuggc cuuaacacag acuugggcga ugccucugcc accgcacccc gggcauccug      180

gauacaucaa cuucuccuau gagguucuaa cgccacucaa gugguaccaa ucuaugauua      240

ggcccccuua uucaaguuac gguuaugaac caaugggcgg guggugagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6524
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt3)

<400>  6524
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cuucugagcg      120

gcgcauuggc cuuaacacag acuugggcga ugccucugcc accgcacccc gggcauccug      180

gauacaucaa cuucuccuau gagguucuaa cgccacucaa gugguaccaa ucuaugauua      240

ggcccccucc aauacugccc gaccuucacc uggaggcuug gccugccacc gauaaaacaa      300

agcaggaaga aguggacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6525
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt3)

<400>  6525
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccuu ggggcugcau      120

uuagcaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc uccuaugagg      180

uguugacacc uuuaaagugg uaccagaaua ugauaagaca cccauauacu ucuuacggcu      240

augaacccau gggagggugg cugcaucacc aaaucauucc ugucguuuca cagcagacgc      300

cacagaguca ugcccuacaa ccccaccacc auaucccuau ggugccagcg cagcagccgg      360

gcauucccca gcaaccuaug augccacucc ccggucagca cagcaugacc ccuacacagc      420

aucaccagcc aaaccugccc cuuccggcuc aacagccuuu ucagccccaa ccaguacagc      480

cucagcccca ccagccacug caaccccagu ccccuaugca uccaauccag ccguugcucc      540

cccagccucc acugcccccu auguucucua ugcaaucgcu gcucccagac uuaccccugg      600

aggccuggcc ggcaacugau aaaaccaaga gggaagaggu ggacugagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6526
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt3)

<400>  6526
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccagaa uaugauuaga cacccauaua      180

cauccuacgg auaugaaccc auggguggcu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6527
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt3)

<400>  6527
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccagaa uaugauuaga cacccauccc      180

uguugcccga cuuaccucug gaagccuggc cagcuacaga uaaaacuaag agggaggaag      240

ucgacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6528
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt3)

<400>  6528
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cuucugagcg      120

gcgcauuggc cuuaacacag acuugggcga ugccucugcc accgcacccc gggcauccug      180

gauacaucaa cuucuccuau gagguucuaa cgccacucaa gugguaccaa aauaugauua      240

ggcaccccua uaccucuuac gguuaugaac cuaugggcgg guggugagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6529
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt3)

<400>  6529
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cuucugagcg      120

gcgcauuggc cuuaacacag acuugggcga ugccucugcc accgcacccc gggcauccug      180

gauacaucaa cuucuccuau gagguucuaa cgccacucaa gugguaccaa aauaugauua      240

ggcaccccuc ucugcuuccu gaccugccau uggaggcuug gcccgccacc gauaaaacaa      300

agcgggaaga aguggacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6530
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt3)

<400>  6530
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccuu ggggcugcau      120

uuagcaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc uccuauauaa      180

gacacccuua cacaucuuau ggcuacgagc caaugggagg gugguugcau caccagauca      240

uucccguggu cucacaacag acuccucaga gucaugccuu acagccacac caccauaucc      300

ccaugguucc ugcgcaacag ccaggcauuc cgcagcagcc caugaugccu cugccagguc      360

aacacagcau gacgcccacc cagcaucacc agccuaaucu accacucccc gcucagcaac      420

cguuucagcc ucagcccgug caaccacagc cucaccagcc ccugcagcca caauccccca      480

ugcauccuau ccagccacuu cugccgcagc ccccuuugcc acccauguuc ucuaugcagu      540

cgcuccugcc ugaccugcca cucgaagccu ggcccgcaac agauaagacu aaaagggagg      600

aaguagacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  6531
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt3)

<400>  6531
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuuugc cugccugcuc ggggcuagcc      120

uugcaaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc uccuaugagg      180

uguugacacc uuuaaagugg uaccagaaua ugauaagaca cccauauacu ucuuacggcu      240

augaacccau gggagggugg cugcaucacc aaaucauucc ugucguuuca cagcagacgc      300

cacagaguca ugcccuacaa ccccaccacc auaucccuau ggugccagcg cagcagccgg      360

gcauucccca gcaaccuaug augccacucc ccggucagca cagcaugacc ccuacacagc      420

aucaccagcc aaaccugccc cuuccggcuc aacagccuuu ucagccccaa ccaguacagc      480

cucagcccca ccagccacug caaccccagu ccccuaugca uccaauccag ccguugcucc      540

cccagccucc acugcccccu auguucucua ugcaaucgcu gcucccagac uuaccccugg      600

aggccuggcc ggcaacugau aaaaccaaga gggaagaggu ggacugagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6532
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt3)

<400>  6532
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccuu ggggcugcau      120

uuagcaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc uccuaugagg      180

uguugacacc uuuaaagugg uaccagaaua ugauaagaca cccaucucug cuacccgacc      240

ucccucugga agccuggcca gcgacugaua aaacgaagag ggaggaaguc gacugaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  6533
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt3)

<400>  6533
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccuu ggggcugcau      120

uuagcaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc uccuaugagg      180

acuuguacuu agaagccaua agaaucgaua ggacagcguu ugugcugacu ccucuaaagu      240

gguaucagaa uaugauucgg cacccauaca cgucuuaugg cuacgagccc augggagggu      300

ggcuccauca ccaaaucauu ccugucguuu cacagcagac cccacagagu caugcucugc      360

aaccccacca ccauaucccu auggugccag cccagcagcc gggcauaccc cagcaaccua      420

ugaugccacu ucccggucag cacagcauga caccuacuca gcaucaccag ccaaaccugc      480

ccuugccggc acaacagccu uuccagcccc aaccaguaca gccucagccc caccagccac      540

uccaacccca guccccuaug cauccaaucc agccgcugcu gccccagccu ccauuacccc      600

cuauguuuuc uaugcaaucg cuccugccag accuucccuu ggaagccugg ccggcuaccg      660

auaaaacaaa gcgcgaggaa guggacugag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  6534
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt3)

<400>  6534
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccuu ggggcugcau      120

uuagcaugcc ccugccucca cacccgggac aucccgguua cauuaacuuc uccuaugagg      180

uguugacacc uuuaaagugg uaccagaaua ugauaagaca cccaacuccc caaucucaug      240

cccugcagcc ucaccaucac aucccaaugg uccccgcgca gcagccuggc auuccacaac      300

agccgaugau gccccuaccu gggcagcacu caaugacgcc aacccagcau caccaaccca      360

accucccucu gccagcucag cagcccuuuc agccgcaacc uguucagccc cagccacauc      420

aaccucuuca gccccagagu ccaaugcacc ccauccagcc ucuguugcca caaccgcccc      480

ucccuccaau guucagcaug cagucccugc ugcccgaccu cccuuuagaa gccuggccag      540

caacagauaa aacuaagagg gaggaagugg acugaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  6535
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt3)

<400>  6535
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cacacccggg ccaucccggg uacaucaacu      120

ucagcuauga ggugcucacc ccucuuaagu gguaccagaa uaugauuaga cacccauaua      180

cauccuacgg auaugaaccc auggguggcu ggcugcauca ccaaauaauc ccugucguuu      240

cucagcagac uccacaguca caugccuugc aaccccacca ccauauuccu auggugccag      300

cucagcagcc ggggaucccc cagcaaccua ugaugccauu acccggacag cacaguauga      360

cgccuaccca gcaucaccag ccaaaccugc cccuaccggc acaacagccu uuucagcccc      420

aaccaguaca gccucagccc caccagccac uccaacccca gagcccuaug cauccaauuc      480

agccgcugcu uccccagccu ccacugcccc cuauguucuc caugcaaucu uugcucccag      540

accugccccu ggaggccugg ccggcgacag auaaaacuaa gagggaagag guggacugag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  6536
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt3)

<400>  6536
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg ccagacugcc ucuccuucug ggguuguuac      120

ugcuaccaag gccgggacgg ccccucgacc uggcugauua caccuaugac cuugcagagg      180

aagaugacag cgagccucug aacuacaagg auccaugcaa agccgcggcu uucuugggug      240

acaucgcccu cgaugaagag gaccugcgcg cauuucaggu ccaacaggcc guugaucugc      300

gacgucacac agcuagaaag uccucuauua aagcagccgu gcccggcaau acuucaacgc      360

cuaguuguca gagcaccaac gggcagccac aaaggggagc uugcggccgg uggcgcggua      420

gauccagguc ucggcgcgcc gcgacaucgc gacccgaaag aguauggccu gacgggguga      480

uaccauucgu caucggaggc aauuuuacug gcucacagag ggcaguguuc cggcaggcca      540

ugcgucauug ggagaagcac accuguguua cauuucucga gcgcaccgau gaagacagcu      600

auauuguguu cacuuacaga ccgugcgggu guugcaguua ugucggaagg cgggguggcg      660

ggccccaggc uaucuccauu ggaaagaacu gugauaaguu uggcaucgug guacaugagu      720

uaggucacgu ugugggguuc uggcaugaac acacacgacc ugaccgcgac agacacgucu      780

cuauagugag ggagaauauc caaccaggac aggaguacaa cuuucugaag auggaacccc      840

aggaggugga aagccuuggc gagaccuaug auuucgacuc cauuaugcau uacgcccgga      900

auacguuuuc acgcggcauc uucuuggaua cuauuguccc uaaauacgaa guuaacgggg      960

ugaagccacc caucggacag agaaccaggc ugaguaaagg ugacauagca caagcucgua     1020

agcuauauaa augcccggcc uguggcgaga cacuccagga uagcacuggg aauuuuucuu     1080

ccccugagua ccccaacgga uauucagcgc acaugcauug cguauggcgg auuagcguga     1140

ccccaggcga aaagaucauu cugaauuuca caagucuuga ccuguaccga ucuagauugu     1200

guugguauga uuacgucgag gugagggacg guuucuggcg caaggccccu cuccggggga     1260

gauuuugcgg cuccaaacug cccgaaccaa ucguuagcac cgauucgagg uuaugggugg     1320

aguuccgauc uuccucaaac ugggucggaa agggcuuuuu cgcaguguau gaagcuaucu     1380

gcgggggaga cguuaaaaag gauuacgguc acauucagag ucccaauuac ccugacgacu     1440

aucgcccaag caaaguaugu auauggcgga uccaaguguc cgagggcuuu cacgucgggc     1500

ugacguucca gucuuuugag auugaacguc augauagcug cgccuacgac uaucucgagg     1560

ugagagaugg acacucagaa aguuccacuc uuaucggcag guacuguggu uaugagaagc     1620

cggacgauau aaaaagcaca ucuucacgcc ugugguugaa guucgucagu gacgggagca     1680

uuaacaaggc uggcuuugcc gugaauuucu uuaaagaagu ugaugagugc ucccggccca     1740

acagaggagg cugugagcag aggugccuaa acacccuggg gucuuacaag uguucgugcg     1800

acccuggaua ugaacucgca ccagauaaac gacgcuguga ggccgcuugc gguggcuucc     1860

ugacuaaacu uaaugggagc aucacauccc ccggauggcc uaaagaauac ccacccaaca     1920

agaauuguau cuggcagcug guggcgccga cccaauaccg gauuucauug caguuugacu     1980

ucuucgagac ggagggcaac gauguaugca aguaugacuu ugucgaagug agaagugguc     2040

ucaccgcaga uucuaaacug caugggaagu ucugcggcag cgagaaaccu gaaguuauca     2100

caucccagua caauaacaug aggguggagu uuaagucaga caauacuguc agcaaaaagg     2160

gauucaaggc ccacuuuuuc ucugacaaag augaauguuc caaggacaac ggcgggugcc     2220

agcaagauug ugugaauacc uuuggaaguu augagugcca gugucguagc ggcuucguau     2280

uacaugacaa caaacacgau ugcaaggagg cugguuguga ccacaaagug acaucuacuu     2340

ccgggaccau uacaucacca aauuggcccg auaaguaccc uaguaagaaa gaaugcaccu     2400

gggccauaag cucgacuccc ggacaucgcg uuaagcugac guuuauggag auggacaucg     2460

aaucccagcc agagugugca uaugaucacc uagaagucuu cgacggccgg gaugccaaag     2520

cuccugugcu cgguagauuu ugcggcucua agaaacccga gccagugcug gccacaggga     2580

gcaggauguu ccuucgauuu uacucagaca acagugucca gcggaaggga uuccaagcau     2640

cccaugcgac cgaguguggc gggcagguuc gcgcugaugu gaaaacuaag gacuuguauu     2700

cucacgccca guucggagac aauaacuacc cgggcggugu ggauugcgaa uggguaauug     2760

ucgcagagga aggguacgga guggagcugg uuuuucagac cuucgaagug gaggaggaaa     2820

cagacugcgg cuaugauuac auggagcucu uugacgguua ugauagcacc gccccuagac     2880

ugggcaggua cugugggucc ggacccccag aagaggucua uucagcuggc gacagcgugc     2940

uuguuaaguu ccacagugau gacacuauca cgaaaaaggg guuucaucug cgguacacau     3000

cuaccaaauu ccaagauacu uugcacuccc gaaagugagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  6537
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt3)

<400>  6537
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggca ccagaugccu gcucgcuuug cuguugcccc      120

aggucuuacu gggaggggca gccggucuag uuccugagcu cggcaggcgg aaguucgcgg      180

cugccagcuc cgggcgccca ucuucacaac cgagugacga agugcugagc gaguuugaac      240

uucgacuguu guccauguuc ggacucaaac agcgucccac accuucuaga gaugcaguag      300

ugccacccua caugcuggac cuguauaggc ggcacucggg ccagccuggu ucaccagccc      360

ccgaucaucg ccucgagaga gcugcaagca gggccaacac uguccggagu uuucaccaug      420

aagaguccuu agaggaacug ccugagacgu cugggaagac cacacgccga uucuuuuuca      480

aucuuagcuc caucccaacu gaagaguuua uuaccucagc ugagcuucag guguucagag      540

aacaaaugca ggacgcccug ggaaacaaua guagcuuuca ccauaggaua aacaucuacg      600

agauuaucaa accggcgaca gcaaauucua aguuccccgu uacccggcua cucgauacuc      660

gucuggugaa ccagaaugcc ucccgcuggg aaucauuuga cgucaccccu gcugugauga      720

gauggacagc ccagggccac gcaaaccacg gcuucguagu ugagguggcu caucuugaag      780

agaaacaagg ggucagcaag aggcacgugc ggauuagucg aucucugcau caggaugagc      840

acuccuggag ccagauccgc ccauugcucg ugacguuugg acacgacggu aagggccauc      900

cccugcacaa aagagaaaag aggcaggcca aacauaagca acggaaacgc uuaaagucgu      960

cuuguaagag acacccucug uaugucgauu ucuccgacgu uggguggaau gauuggauag     1020

uggcgccacc cggauaccau gccuucuauu gccacggcga guguccguuu ccucucgcag     1080

accaccuuaa cucaacuaau caugcuaucg uacagacccu ggugaacagu gucaauagca     1140

aaauucccaa ggccugcugu gugccaacag aauuguccgc uaucucuaug cuauaccugg     1200

augagaacga aaaaguugug cucaagaauu aucaggacau ggucguggag gguugcgggu     1260

guaggugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  6538
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt3)

<400>  6538
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auccccggca acagaaugcu gauggugguc cuccuuugcc      120

agguucuguu agggggagcc agccacgcuu ccuugauucc ugagaccggu aagaaaaagg      180

uggcagaaau acaaggccau gccgggggaa ggcggucugg ccagucacac gagcugcuac      240

gcgacuucga agcgacacuc cugcagaugu uuggucuucg acguagacca cagccgagua      300

aaagcgcugu aauccccgau uacaugaggg accuguaucg guugcaaucc ggggaggaag      360

aggaggaaca gauucauucu acuggacucg aguacccuga acgcccagcc ucgagagcaa      420

auacggugag gucauuccac caugaggagc accuggaaaa cauccccggc accagcgaga      480

auagugccuu ucgguuccug uuuaaccucu ccucuauucc ugaaaaugag gucaucagcu      540

ccgcugaauu acgccuguuc cgagaacagg uggaucaggg cccagacugg gagagagggu      600

uucacaggau aaacaucuau gagguuauga agcccccugc agaggugguc ccaggacauc      660

uuauuacacg guugcuggau acucgucuag ugcaccauaa uguaacccgc ugggaaacau      720

ucgacguuuc accggccgug cucagaugga ccagggagaa acaacccaac uacggucugg      780

cuaucgaagu cacucaccuu caccagacac ggacccauca gggccagcac gugcgaauua      840

gucgcagccu gccucaaggg ucuggaaauu gggcccaguu gagaccacuc cuggugacgu      900

uuggccauga ugguaggggg cacgcguuaa cucggcgcag aagggcaaag cguuccccca      960

agcaucacuc acagcgggcc cgaaagaaaa acaaaaauug uagaaggcac agccuguaug     1020

ucgacuucag ugauguugga uggaacgacu ggaucguggc uccuccaggc uaccaagccu     1080

uuuauugcca uggcgauugu cccuucccgc ucgcagacca ccuuaauucu accaaccaug     1140

cuauaguaca gacacugguc aauuccguga acagcucgau uccuaaggcc ugcugugugc     1200

ccacugaguu gucugcgauc uccaugcuau accuggauga guacgacaaa guugugcuca     1260

agaacuauca ggaaaugguc guggaggggu gcggaugucg cugaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  6539
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt3)

<400>  6539
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggccuag ggagaagggc ccaguggcuc ugcugguggu      120

ggggacuucu guguagcugc ugugguccuc caccguugcg gcccccuuua ccagcugcag      180

ccgcggcugc cgcaggcggg caacugcuag gagacggcgg uucccccggg cgcaccgagc      240

agccuccacc cucuccucag ucaaguagcg gauuccucua ccgacgucug aagacacagg      300

agaaaagaga aaugcaaaag gaaauccuuu ccgugcuggg cuugccacac aggccgcggc      360

cccuccaugg ccugcagcag ccucagccac ccgcccugcg ccaacaggag gaacagcagc      420

aacagcagca acucccuaga ggggagccac ccccgggaag guuaaaaucu gcuccucugu      480

uuaugcuuga uuuguauaac gcacugucgg ccgacaauga ugaggacggu gcuucagaag      540

gcgagcggca gcagagcugg ccccacgaag ccgcgaguuc cucucagcgc cgacaaccac      600

cucccggggc agcccaucca cuaaacagaa agagccuccu ggcucccgga uccggcucag      660

guggggccag uccucuuacu agcgcacagg auucugcuuu ccugaaugac gccgauaugg      720

ucauguccuu uguuaacuug guggaguacg acaaagaguu cucaccaagg cagcggcacc      780

auaaggaauu uaaguucaau cucagccaga uuccggaggg agaaguagug acggcggccg      840

aguuucguau auauaaagau ugcgucaugg gcaguuucaa gaaccaaacc uuucugaucu      900

cuauuuacca gguguuacag gaacaccagc accgcgacuc cgaucuguuc cuccuugaca      960

caagaguugu gugggcaagc gaggagggcu ggcuggaauu ugauaucacu gcuaccucga     1020

auuugugggu cgugacaccc caacauaaca uggggcuaca gcugucugua guuaccaggg     1080

acggagugca cguccauccu cgggccgcug gucucguggg ccgagacggg ccauaugaua     1140

aacagcccuu caugguggcc uuuuucaagg ucuccgaggu ucacgugcgc acuacaagau     1200

cagcaaguag caggcggcgc cagcaaucca gaaauagguc uacccagagc caggacguag     1260

cccguguguc aagugcuucc gauuacaaca gcucugaacu gaaaacggcg ugucggaagc     1320

acgagcuuua ugucucauuc caagaccugg gauggcagga uuggauuauc gcaccuaagg     1380

gcuacgccgc uaauuacugc gacggugaau guaguuuucc auugaacgcc cauaugaaug     1440

caacuaacca cgccauagug cagacccucg uucaucugau gaaucccgag uaugugccga     1500

aaccuugcug ugcuccaaca aaguuaaacg ccaucagcgu ccuguacuuc gaugacaacu     1560

ccaaugugau ucugaaaaag uaucgaaaca ugguaguuag agcaugcggg ugucacugag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  6540
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt3)

<400>  6540
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugagaa gccugagggc cgcugcaccc cauuccuucg      120

ucgcccucug ggcgccucuu uuucuguugc ggucugcuuu agccgacuuc ucacuggaua      180

acgagguuca caguagcuuu auccaucgcc gacuacguuc ccaggaaaga agggagaugc      240

aacgggaaau ucucucuaua cugggccuuc cacaccgccc gagaccccau cugcagggga      300

agcacaauuc ggcaccuaug uucauguugg accucuacaa cgccauggcu guggaggaag      360

gagguggccc agggggacag ggcuuuucau aucccuacaa agcaguauuc agcacccagg      420

guccuccacu ggccagucug caagauuccc acuuucucac agacgcugau auggugaugu      480

cuuucgucaa uuuaguggag caugacaagg aguuuuucca ccccagguau caucaccggg      540

aauuucgcuu cgaucugagc aaaaucccug agggggaagc cguuacugcg gcagaguuuc      600

gaauuuacaa ggacuauauc agagagaggu ucgauaacga aacguuccgg auuuccgugu      660

accagguccu ucaggagcac uugggacgug aaucagaccu guuucuacuc gauagucgca      720

cccugugggc cagcgaggaa ggcuggcuug uguucgacau cacagcuacu ucuaaucauu      780

ggguaguuaa cccaagacac aaucugggcu ugcagcucuc cguggagacc cuggaugggc      840

aaucaauaaa cccgaaauua gccggacuga ucgguaggca uggcccccag aauaagcagc      900

cuuuuauggu cgcauucuuu aaggcuacag aggugcacuu ccggagcauu cgaaguaccg      960

ggucuaaaca gcgcucccaa aacagaagca agacucccaa aaaucaggaa gcccucagga     1020

uggcgaacgu ggccgaaaau ucgucuuccg accagcggca agcaugcaag aaacaugagc     1080

uuuaugucuc auuucgcgac cugggauggc aggauuggau cauugcucca gagggcuacg     1140

ccgcuuacua uugugaaggu gagugcgccu ucccuuugaa caguuacaug aaugcaacaa     1200

accacgccau cguucagacc cuagugcacu uuauaaaccc agagacggua cccaagccgu     1260

guugcgcucc uacucagcug aaugcgauua gcgugcucua uuucgacgau uccucuaacg     1320

ucauccugaa gaaauacaga aauauggugg uuagggcaug ugggugccau ugaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  6541
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt3)

<400>  6541
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggccagcg cugcacugcu cugccuucug uugaccgccg      120

cggcuuucuc uccccagggc uuagcccaac cuguggggau caacacaucc acuacguguu      180

gcuacagauu uauuaauaaa aagauaccaa aacagaggcu ggagucauau cggcgcacca      240

caaguagcca cuguccgcga gaagcaguca ucuucaagac uaaacuagac aaggagauuu      300

gcgccgaucc cacccagaag uggguucagg acuuuaugaa acaucucgau aagaaaacac      360

aaaccccuaa gcugugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  6542
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt3)

<400>  6542
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucaccc uuaucauucu guugcccgug gucagcaagu      120

ucuccuuugu uucuuuauca gccccucagc acuggaguug cccagagggc acacuggcug      180

ggaacggaaa uagcacuugu guggguccgg cacccuuccu aauauuuucc cauggcaacu      240

cuaucuucag aauugacacg gaagggacca auuacgagca acucguagug gacgccggag      300

ucucggugau cauggacuuu cacuauaacg aaaagaggau uuacuggguu gaucuggagc      360

ggcagcuucu gcagcgcgug uucuugaaug gcucacgaca ggaacguguc ugcaacaucg      420

agaagaaugu gagcgguaug gcgauaaacu ggaucaauga ggaaguaauu uggaguaacc      480

aacaggaggg gaucauuaca guuacugaca ugaaaggaaa uaacucccau auccuccugu      540

cugcucugaa guauccugcc aauguggcag ucgauccagu ggaaagauuu auauucugga      600

gcuccgaggu ggccggcuca cucuacaggg cugacuuaga uggcgucggg guuaaagcac      660

ugcuugagac cagugaaaag auuacagccg ugagcuugga cguacuggau aagcggcuau      720

uuuggaucca guauaaccgc gagggaucua auucccucau uuguucaugc gacuacgaug      780

guggcagcgu gcacaucagu aaacauccca cccagcacaa ccuguucgcu augucucuuu      840

uuggggacag aaucuucuau uccacuugga agaugaaaac aauuuggaua gccaacaagc      900

acaccggaaa agauaugguc aggaucaauc ugcauagcuc guuugugccu uugggcgaac      960

ucaagguugu gcacccacug gcgcaaccca aggcagagga cgacacgugg gaaccugagc     1020

agaaauuaug uaagcugcgg aaagguaacu gcucauccac ugucuguggg caggaucucc     1080

agucacaucu uugcaugugu gccgagggau acgcucugag ucgcgaccga aaguacugcg     1140

aagaugugaa ugagugugcc uucuggaacc acggcugcac cuugggcugc aaaaauacac     1200

cagggagcua uuacuguacu ugcccgguag gauucguucu acugcccgac gguaagagau     1260

gucaccaacu cguguccugc ccuaggaacg ucucugaaug uagccaugau ugcgugcuga     1320

ccucagaggg cccacuuugu uuuugccccg aagggagugu ccuggagcgg gacggaaaaa     1380

cauguuccgg cugcagcucu ccugauaaug guggguguuc acaguugugc gugccacuca     1440

gucccguuag cugggagugc gacuguuucc cgggcuauga ucugcaguua gacgaaaagu     1500

ccugcgcagc uucuggaccu caacccuuuc ugcuauucgc caacucgcag gauauucguc     1560

acaugcauuu ugacggcacc gacuacggga cgcuccugag ccagcagaug ggaauggugu     1620

augcgcuuga ucacgaccca guagagaaua agaucuacuu cgcccauacu gcauugaaau     1680

ggauagaacg cgcuaacaug gaugguuccc aaagagagag gcugauugaa gagggcgucg     1740

acgugccuga ggggcucgcc guugauugga ucggacggcg auuuuauugg acagaccgcg     1800

gcaagucacu gaucgguaga agugaucuua augggaaaag gucuaagauu aucaccaaag     1860

aaaacauuag ccagccccgg ggcauagcug ugcacccaau ggccaagcgc cuguucugga     1920

cugacacagg aaucaauccc agaauugagu ccucuagcuu gcagggccuc gggaggcugg     1980

ucaucgcauc uuccgauuua aucuggccua guggaauuac cauagacuuu cugacggaua     2040

agcuauacug gugugacgcc aaacagagcg ugaucgaaau ggcuaaccuc gaugguucua     2100

agcgucggcg acugacccaa aaugacguag gccacccauu cgcgguggca guuuuugagg     2160

acuacgucug guucuccgau ugggccaugc cgucagugau gagagugaac aaaaggacag     2220

ggaaggaccg cguccggcuu cagggaagua uguugaaacc cagcucgcug guuguggugc     2280

auccucucgc uaagccaggc gccgaucccu gccuguauca gaacgguggg ugugagcaca     2340

uuugcaagaa aagauuaggc acugcauggu guuccugcag ggaaggauuu augaaggccu     2400

cugacggcaa aaccugucug gcucuugaug ggcaucaguu gcucgccgga ggcgagguag     2460

accugaagaa ucaagucaca ccucuagaua uccugagcaa aacucgcgug ucagaagaca     2520

acauuaccga gagucagcac augcucguug cagaaaucau gguguccgau caggacgauu     2580

gcgcgccagu cgguuguucu auguacgcuc gaugcauaag cgagggggag gacgccacau     2640

gccagugucu gaagggauuc gcaggcgaug guaaacuuug cuccgacauc gacgaaugug     2700

agaugggcgu gcccguuugc ccgccugccu caagcaaaug uauuaauacc gaagggggau     2760

augugugccg guguagugag ggcuaccaag gggauggaau ccacugcuug gacauugaug     2820

aaugucagcu gggcgagcau ucuugcggug agaacgcuuc cuguacuaau acggaagggg     2880

gauauacaug caugugcgcc ggccguuuaa gcgagccagg ucucaucugu cccgacucga     2940

ccccuccccc acaccugaga gaagaugacc aucacuacuc aguaaggaac ucugauagug     3000

agugcccucu uucccaugac ggcuauuguc ugcacgaugg ggucugcaug uacauagaag     3060

cauuggacaa guacgcuugu aauugcgugg ugggauauau uggcgagcgc ugucaguacc     3120

gggaucucaa auggugggag cugagacacg ccgggcaugg acaacagcag aaggucaucg     3180

uuguggcggu augcgugguc gugcuaguua ugcugcuccu gcuuagcuug uggggcgccc     3240

acuauuacag gacucagaaa cuguuaucua agaaccccaa aaauccauau gaagagagcu     3300

cccgagacgu gcgcucacgg agaccggcug acaccgaaga ugguaugagu agcuguccuc     3360

aacccugguu cgucgugauu aaggagcauc aggaccucaa gaacggggga cagccaguug     3420

caggcgagga uggucaggcc gcugacggcu cuaugcaacc cacauccugg aggcaggaac     3480

cucagcugug cgggauggga accgagcagg gcuguuggau cccaguguca agugauaaag     3540

ggagcugccc ccaagucaug gaacguuccu uucacaugcc uucuuacgga acucagacac     3600

uugagggcgg uguagaaaag ccgcauucgc ugcuaagcgc caauccacuc uggcagcaac     3660

gcgcacugga ucccccucac cagauggagu ugacgcagug aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  6543
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt3)

<400>  6543
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggca gaaggaugga gaugcugugc gcugggcggg      120

ugcccgcacu ccuucugugu uugggauucc acuuacugca ggccguccua agcacaacug      180

uuaucccuuc cugcauucca ggugaaucuu cagacaacug uacggcgcuc gugcaaaccg      240

aggauaaucc gcgcguagcu caggugagua uaacaaagug cagcuccgac augaacggcu      300

acugucugca ugggcagugc aucuaucuug ucgauauguc ucagaauuac ugucgaugcg      360

aagugggaua uacuggcguu cguugugagc acuuuuuccu gaccgugcau caacccuugu      420

cgaaagaaua cgucgcccuc acagugauuc ugaucauucu guuucucauc accguaguug      480

guucaacuua uuacuucugc agaugguaua ggaaccgcaa gagcaaagag ccuaagaaag      540

aguacgaacg ggugacaagu ggggacccag aguuacccca ggucugagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  6544
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt3)

<400>  6544
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgagggcg aaaucaccac auucacugcu cugacggaga      120

aguuuaaccu ucccccuggg aauuacaaaa agccaaaacu ccuguauugc agcaacggag      180

gucacuucuu gagaauuuua ccggacggca ccguggaugg gacaagggac cgguccgauc      240

agcauauaca acugcagcua ucugcagaau cagucggaga gguuuacauc aagaguacug      300

aaaccggcca guaucucgcc auggacacag auggucugcu uuacgggagc cagaccccca      360

augaggagug ucuguuuuug gaacgccucg aggaaaacca cuauaauacu uacauuucca      420

aaaagcaugc ggagaagaac ugguucgugg gacugaaaaa gaauggcucu ugcaaacgag      480

gcccucguac acacuauggg caaaaggcua uccuguuucu cccauuaccc guaucgucag      540

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  6545
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt3)

<400>  6545
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggcgucg ggggagguga cguugaggau gugaccccca      120

gaccuggcgg gugccagauc agcggaaggg gcgcccgggg uuguaacggg auuccaggag      180

cugcagccug ggaagcggcu cugccgcgcc gacgucccag aaggcacccu uccguaaauc      240

cacggucucg cgccgcaggc ucacccagaa caaggggccg gcgcacugag gaacgaccua      300

gugggagcag acucggagac aggggucggg gccgugcccu uccaggggga cgccugggcg      360

guagagggag gggacgggcu cccgagcgag ugggcggccg cgggagagga agggguacgg      420

cagccccucg ggcugcccca gcggcacgcg gcuccagacc ggggcccgcc ggaaccaugg      480

cugccggcuc uauaacaacu uugccugcau uaccagaaga uggugggucg ggcgcuuuuc      540

ccccuggaca uuucaaggac ccaaaaaggc uguacugcaa gaacggcggg uucuuucuac      600

guauccaccc cgauggacgg gucgacggug ugcgagagaa aucagauccg cauauuaagc      660

uccaacugca ggccgaggaa agaggcguug ugagcaucaa aggggucugu gcgaauaggu      720

aucuugccau gaaggaggac ggacgccugu uggcaaguaa gugcgugacc gaugaauguu      780

ucuuuuucga gcggcucgag uccaacaauu acaacacaua uagaucuagg aaauacacca      840

gcugguaugu agcucugaag cgcacuggcc aguacaaacu ggguuccaag acagggccug      900

gccagaaagc cauucucuuu uuacccaugu cagcuaagag uugaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  6546
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt3)

<400>  6546
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uccugaccug gauucucccc acacuucugu      120

acagaagcug cuuccauaua aucuguuugg ugggcacuau uuccuuagcc ugcaacgaca      180

ugacgccuga gcagauggcu accaauguca acuguucuuc accagaaagg cacacacgga      240

guuaugauua cauggaggga ggagacaucc gcguucgacg ucuguuuugc agaacucaau      300

gguaucuaag gauugauaaa cgggguaagg ugaaaggcac ccaggaaaug aagaauaacu      360

acaauaucau ggagauacgc acaguagcag uggggaucgu cgccauuaaa ggaguggaaa      420

gcgaguucua ucucgcgaug aacaaggagg gcaagcugua cgcuaaaaag gaauguaaug      480

aggacugcaa cuuuaaagaa cuuauccugg agaaucauua uaacaccuac gccuccgcaa      540

aguggacuca caaugguggg gagauguucg uugccuugaa ccagaaaggg auuccgguga      600

gaggcaagaa gaccaaaaag gaacagaaaa cagcucauuu ucuccccaug gcaaucacgu      660

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  6547
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt3)

<400>  6547
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugcucc ccagcguggu ccuuaaacug uucuuggccg      120

cuguuuuauc cgcacuggug accggcgagu cucuagaaag acucaggcgg gggcuggccg      180

cgggaacauc aaacccugac ccaccgacug uaaguacgga ucagcuucug cccuugggug      240

gcgggcgcga ccgaaaggug cgugaucucc aagaggcuga ccuggaucug cucagaguca      300

ccuuaagcuc caaaccucag gcccuggcaa caccaaauaa ggaggaacac ggaaaaagga      360

agaagaaagg caagggucuu gggaaaaagc gggaccccug cuugcgcaaa uacaaggauu      420

uuuguaucca uggagaaugc aaguauguga aagagcugag agccccuucu uguauuugcc      480

acccaggcua ccauggcgag aggugucacg ggcuaucgcu ccccguugaa aaccggcugu      540

auacuuacga ccauaccaca auacuugcug uggucgcagu gguacuguca agcguuugcu      600

ugcucgugau cgucggacug uuaauguucc gcuaucaccg aagagguggc uacgaugugg      660

agaaugaaga gaaggugaaa cuggggauga ccaacaguca cugaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  6548
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt3)

<400>  6548
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccuucug uugcagcacg      120

ucuuacugca ucuacuccug cuuccuaucg cuauuccaua cgcagagggc caaagaaaaa      180

ggcggaacac aauacacgag uucaagaaaa gcgccaagac uacgcugauc aaaauugacc      240

cggcguugaa gaucaagacc aaaaagguua auacagcuga ucagugcgcc aaccgcugua      300

cucgaaauaa agggcucccc uuuaccugca aggcauucgu guuugacaaa gcccguaagc      360

agugucugug guucccuuuu aacuccaugu cuucaggagu aaagaaagag uucggucaug      420

aauuugaucu guaugagaau aaggacuaca uuagaaacug caucauaggc aaagggagga      480

guuauaaggg aacagugagc aucaccaaau ccggcauuaa gugucagcca uggucuucga      540

ugauccccca cgaacauuca uuccucccua gcaguuaccg ggguaaagau uuacaagaga      600

auuauugccg caacccaaga ggggaggaag gaggccccug guguuuuacu uccaauccug      660

aggucaggua cgaagugugc gacauuccac aguguucuga gguugagugc augacaugua      720

acggcgaaag cuaucggggg cugauggauc acaccgaguc cggaaagauc ugccagcgcu      780

gggaccacca gacgccgcau cgacacaagu uccuucccga aagauacccu gauaaagguu      840

uugacgauaa uuacugcagg aacccagacg gccaaccccg gccuuggugu uauacuuugg      900

auccacauac ccguugggaa uacugcgcua uaaagacaug ugcagacaau acuaugaacg      960

acaccgaugu gccccuggaa acaaccgagu gcauucaggg gcagggagag ggcuaucgcg     1020

guacggucaa uacuaucugg aacgggauuc cgugucagag augggacuca caauacccuc     1080

acgaacacga uaugacaccc gagaacuuca aaugcaagga ccuaagggaa aauuauuguc     1140

ggaacccaga uggaagugag agcccuuggu gcuuuaccac ugaccccaau auccgagugg     1200

gcuacuguuc ucagauccca aacugcgaua ugucccaugg ccaggacugu uaucgcggga     1260

augguaaaaa cuacauggga aaucucucac aaacaagaag cggccugacc ugcaguaugu     1320

gggauaagaa cauggaagac cuucacaggc auauuuucug ggagcccgau gccucuaagc     1380

ugaaugagaa cuacugccgg aauccugacg acgaugcuca cgggccaugg uguuauacgg     1440

gaaacccguu gauacccugg gacuacugcc cuaucucccg cugugaaggc gauaccacac     1500

caacuauugu aaaucucgac caucccguua ucagcugcgc caaaaccaag cagcugagag     1560

uggucaacgg uauaccuaca aggacuaaua uuggguggau ggugucguua cguuaucgga     1620

acaaacacau cuguggcgga ucucugauca aggaguccug ggugcucacc gcgcgacagu     1680

gcuucccauc aagagaucuu aaagacuacg aagcauggcu gggcauucac gauguccaug     1740

ggaggggaga cgagaagugu aagcagguuu ugaacgugag ucagcuagua uauggucccg     1800

aaggcagcga ucuggugcuc augaaacugg cccgcccggc uguccuugac gauuuugugu     1860

ccacaaucga ccugccuaau uacgggugca ccauuccaga gaagacuucu uguagcguuu     1920

auggaugggg cuacacgggu uugauaaacu acgaugggcu ccugcgggug gcccacuuau     1980

auaucauggg caaugagaaa ugcucacaac aucacagagg aaaggucaca cugaacgaaa     2040

gugagauuug ugcaggcgcu gagaaaaucg gguccggacc cugcgaaggu gacuacggcg     2100

ggccucuagu gugcgagcag cacaagauga ggaugguacu cggaguuauc gugcccggcc     2160

gcgguugugc cauuccaaau cgaccuggga uauucguccg gguggcguau uacgccaagu     2220

ggauccauaa aauuauccug accuauaagg ucccccagag cugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  6549
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt3)

<400>  6549
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggcug cagccaucgg cauugaccug gggaccacau      120

acagcugcgu gggagucuuc cagcacggua aaguugagau aaucgcgaac gaucaaggca      180

auagaacuac gcccuccuau guggcuuuua ccgacacaga aaggcucauu ggggaugccg      240

caaagaacca gguagcccuu aauccucaga acacuguguu cgacgcuaaa cggcugaucg      300

gacgcaaguu uggcgaucca gucgugcagu cugacaugaa acauuggccg uuccaaguua      360

uuaaugaugg ugacaagccc aaggugcagg ucucauacaa aggggagacc aaggcauuuu      420

auccugaaga gaucaguagc augguguuga caaaaaugaa ggaaauagcc gaggcuuacu      480

uaggauaucc aguaaccaac gccguuauca cugugcccgc guacuucaau gauucccagc      540

gacaggcaac aaaagacgcc ggcgucauug cuggccugaa cgugcuacgu aucauuaaug      600

agccuaccgc cgcagcuauc gccuaugggc ucgauagaac gggaaagggu gaaaggaacg      660

ugcugauauu ugaccuuggc gggggaacuu ucgaugucuc uauucugacc aucgacgacg      720

gcauuuuuga gguuaaggcg acagccggug auacucaccu ugggggagaa gacuucgaua      780

aucggcucgu gaaccauuuu guagaggagu ucaaacgcaa gcacaaaaag gacaucucgc      840

aaaauaaaag agcagugagg cggcugcgca ccgcuuguga acgagccaag agaacacugu      900

caagcaguac ccaggcuucc cucgagaucg auucuuuauu ugaaggcauu gacuucuaca      960

cgagcauaac uagggcccgg uucgaggaac ugugcuccga ucuuuuucgu ucaacauugg     1020

agccagucga gaaagcacug cgcgacgcca agcuagauaa ggcucagauc caugaccucg     1080

ugcugguugg cgggaguacc cggauuccca aagugcagaa guugcugcaa gauuucuuua     1140

acggaaggga cuugaauaaa agcaucaacc cugacgaagc ggucgcauac ggugccgcug     1200

ugcaggccgc aauacucaug ggcgauaagu cugagaacgu acaggaccug uuacugcucg     1260

auguugcccc acuuucccug ggguuggaaa cugcuggagg cgugaugaca gcccuaauua     1320

aaagaaauuc aaccaucccg acgaagcaaa cccagaucuu cacaacuuau agcgacaacc     1380

agcccggugu ccugauucag guguacgagg gggaacgagc aaugaccaag gauaauaacc     1440

uccugggccg cuuugagcuu aguggaaucc cuccagcgcc cagaggcguc ccucaaauug     1500

aggugacauu cgacauagau gcuaauggga uccugaacgu uacugccacc gacaaaucua     1560

caggaaaggc aaauaaaauu accaucacua acgauaaggg uagguugucc aaagaagaga     1620

ucgaacggau ggugcaggag gccgaaaagu auaaggcuga ggacgaggua cagcgcgaaa     1680

gagucagcgc caaaaaugca cucgagucgu acgcuuuuaa caugaagucu gccguggaag     1740

augagggccu gaaagggaag auuuccgagg cggacaaaaa gaagguuuua gauaaauguc     1800

aggaagugau aucauggcug gacgccaaua cgcuagcuga gaaggacgag uucgaacaca     1860

aaaggaagga acucgagcaa gucugcaacc caaucauuag uggacuguau cagggcgccg     1920

gugggcccgg cccgggaggc uuuggggcac agggaccuaa agguggcagc ggguccggac     1980

ccacaaucga ggaaguggau ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6550
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt3)

<400>  6550
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggcug cagccaucgg cauugaccug gggaccacau      120

acagcugcgu gggagucuuc cagcacggua aaguugagau aaucgcgaac gaucaaggca      180

auagaacuac gcccuccuau guggcuuuua ccgacacaga aaggcucauu ggggaugccg      240

caaagaacca gguagcccuu aauccucaga acacuguguu cgacgcuaaa cggcugaucg      300

gacgcaaguu uggcgaucca gucgugcagu cugacaugaa acauuggccg uuccaaguua      360

uuaaugaugg ugacaagccc aaggugcagg ucucauacaa aggggagacc aaggcauuuu      420

auccugaaga gaucaguagc augguguuga caaaaaugaa ggaaauagcc gaggcuuacu      480

uaggauaucc aguaaccaac gccguuauca cugugcccgc guacuucaau gauucccagc      540

gacaggcaac aaaagacgcc ggcgucauug cuggccugaa cgugcuacgu aucauuaaug      600

agccuaccgc cgcagcuauc gccuaugggc ucgauagaac gggaaagggu gaaaggaacg      660

ugcugauauu ugaccuuggc gggggaacuu ucgaugucuc uauucugacc aucgacgacg      720

gcauuuuuga gguuaaggcg acagccggug auacucaccu ugggggagaa gacuucgaua      780

aucggcucgu gaaccauuuu guagaggagu ucaaacgcaa gcacaaaaag gacaucucgc      840

aaaauaaaag agcagugagg cggcugcgca ccgcuuguga acgagccaag agaacacugu      900

caagcaguac ccaggcuucc cucgagaucg auucuuuauu ugaaggcauu gacuucuaca      960

cgagcauaac uagggcccgg uucgaggaac ugugcuccga ucuuuuucgu ucaacauugg     1020

agccagucga gaaagcacug cgcgacgcca agcuagauaa ggcucagauc caugaccucg     1080

ugcugguugg cgggaguacc cggauuccca aagugcagaa guugcugcaa gauuucuuua     1140

acggaaggga cuugaauaaa agcaucaacc cugacgaagc ggucgcauac ggugccgcug     1200

ugcaggccgc aauacucaug ggcgauaagu cugagaacgu acaggaccug uuacugcucg     1260

auguugcccc acuuucccug ggguuggaaa cugcuggagg cgugaugaca gcccuaauua     1320

aaagaaauuc aaccaucccg acgaagcaaa cccagaucuu cacaacuuau agcgacaacc     1380

agcccggugu ccugauucag guguacgagg gggaacgagc aaugaccaag gauaauaacc     1440

uccugggccg cuuugagcuu aguggaaucc cuccagcgcc cagaggcguc ccucaaauug     1500

aggugacauu cgacauagau gcuaauggga uccugaacgu uacugccacc gacaaaucua     1560

caggaaaggc aaauaaaauu accaucacua acgauaaggg uagguugucc aaagaagaga     1620

ucgaacggau ggugcaggag gccgaaaagu auaaggcuga ggacgaggua cagcgcgaaa     1680

gagucagcgc caaaaaugca cucgagucgu acgcuuuuaa caugaagucu gccguggaag     1740

augagggccu gaaagggaag auuuccgagg cggacaaaaa gaagguuuua gauaaauguc     1800

aggaagugau aucauggcug gacgccaaua cgcuagcuga gaaggacgag uucgaacaca     1860

aaaggaagga acucgagcaa gucugcaacc caaucauuag uggacuguau cagggcgccg     1920

gugggcccgg cccgggaggc uuuggggcac agggaccuaa agguggcagc ggguccggac     1980

ccacaaucga ggaaguggau ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6551
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt3)

<400>  6551
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaccgcua agggcaucgc aauugggaua gaccugggaa      120

caacuuacag cugcgugggu gucuuccagc acggcaaagu ugagaucauu gccaacgauc      180

aagggaauag aacgaccccc uccuaugugg cguuuacaga cacugaaagg cucaucggag      240

augcugccaa gaaccaggua gcaaugaauc cucagaacac cguguucgac gccaaacggc      300

uuauuggccg caaguuuaau gauccagucg ugcaggcuga caugaaacug uggccguucc      360

aaguuaucaa cgaggguggg aagcccaagg uguuggucuc uuacaaagga gaaaauaagg      420

cauuuuaucc ugaggaaaua ucaaguaugg uguuaacaaa acugaaggag accgccgagg      480

cuuuccuagg ccauccagua acuaacgccg uuaucacagu gcccgcguac uuuaaugaua      540

gccagcgaca ggcaaccaaa gacgccggcg ucauugcugg gcucaacgug cugcguauca      600

uuaaugaacc uacggccgca gcuaucgccu auggacuuga uaaggguggc cagggggaga      660

gacacgugcu gauauucgac uugggaggcg guacuuuuga ugucuccauu cucaccaucg      720

acgaugggau uuucgaaguu aaggcgacag ccggagacac ucaucugggc ggcgaggacu      780

uugauaacag gcuggugucu cacuucguag aggaauuuaa acggaagcau aaaaaggaca      840

ucucgcaaaa uaaacgcgca gugagaaggc uccggaccgc uugugagcgc gccaagcgaa      900

cauuaucaag caguacccag gcuaaccugg aaaucgauuc ccuuuacgag gggauugacu      960

ucuauacguc uauaacuaga gccagguucg aagaguugug cgcagaucug uuucggggaa     1020

cacuagagcc agucgaaaaa gcccuccgug acgcuaagau ggauaaggcg aaaauccacg     1080

acauugugcu gguugguggc agcacccgca uccccaaggu gcagagacuu cugcaggauu     1140

acuucaaugg gagggacuug aacaaaucca uaaacccuga ugaggcaguc gccuacggag     1200

cugccgugca agcagccauu cucaugggcg acaagucaga aaaaguacag gaccuguuac     1260

ugcucgaugu ugcuccacuu agucuggguu uggagacugc cgggggcgug augacagcac     1320

uaaucaagcg gaauagcacc aucccgacga agcagaccca aauuuuuaca acuuauucug     1380

acaaccagcc cggaguccug auccaggugu acgaaggcga gcgagcgaug accaaagaua     1440

auaaccuccu ggggcgcuuc gaccuuacag ggauuccucc agcucccaga ggugucccuc     1500

agauagaggu gacuuuugau aucgacgcca auggcauucu gaacguuacc gcaacagaua     1560

aguccaccgg gaaagugaau aagaucacua ucacgaacga caaaggaagg uugucaaagg     1620

aagagauuga acggauggua cucgaugccg agaaguauaa agcugaagac gagguccaac     1680

gcgagaagau agccgcuaaa aaugcacugg aaagcuacgc cuucaacaug aagagugugg     1740

uuucugauga gggcuuaaaa gguaagaucu ccgaaagcga caagaauaaa auucuggaua     1800

aguguaacga gcuacucucg uggcuggagg ugaaucagcu ugcggaaaaa gacgaguuug     1860

accacaagag aaaagaauug gagcagaugu gcaacccaau cauuacaaag cuguaucagg     1920

gaggcuguac cggacccgcc ugcggcacug gguacguccc gggaaggccu gcuaccgguc     1980

ccacaaucga agagguggau ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6552
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt3)

<400>  6552
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgccagag gccccgcuau cgggauugac cugggaacca      120

cauacuccug cguggguguc uuccagcacg gcaagguuga gauaaucgca aacgaucaag      180

ggaauaggac uacgccuucu uauguggccu uuaccgacac agaacggcuc auuggagaug      240

cggcuaaaaa ccagguagcc augaauccaa cuaacaccau cuucgacgca aagcgccuua      300

uuggccgaaa auuugaggau gccacagugc agucagacau gaagcauugg ccguuccgug      360

ucgugaguga aggugggaaa cccaagguuc agguggagua caagggagaa accaaaacau      420

uuuucccuga ggagaucagc uccauggucc ugacuaagau gaaagaaaua gcugaggcau      480

auuugggcgg caaggugcac ucugccguaa ucaccguucc agcuuacuuu aaugauucgc      540

aaagacaggc cacgaaagac gcggggacua uuaccggauu aaacgugcug aggaucauua      600

augaacccac agcagccgcu aucgccuaug gucuagauaa gaagggcugu gcagggggag      660

agaaaaacgu ccucauauuc gaccugggcg gugggacuuu ugauguguca auucuuacca      720

ucgaggacgg aauuuucgaa gucaagagca cagcuggcga uacccaucug ggcggggagg      780

acuuugacaa ucggauggug agucacuugg ccgaagaguu caaacgcaag cauaaaaagg      840

auaucggacc uaacaaaaga gcgguuaggc ggcuccgcac ggccugcgaa cgagcaaaga      900

gaacucuguc cucuagcaca caggcuucca ucgagauuga cucacuguac gagggugugg      960

auuuuuauac caguauaacu agggcccggu ucgaggaacu caaugcugac uuauuccgug     1020

gcacacugga accaguagag aaggcccuuc gcgaugcaaa auuggacaag gggcagaucc     1080

aagaaauugu gcuggucgga ggcagcacca gaauccccaa aauacagaag cuacuccagg     1140

acuuuuucaa cgguaaagag cugaauaagu cuauuaaccc ugaugaggcc guggcuuacg     1200

gggcggcagu ucaggccgcu auccuuaucg gcgauaaguc cgaaaaugug caagaccugu     1260

ugcuccugga ugucacgcca uuaucacugg gaauugagac cgccggcggg gugaugacac     1320

cgcucaucaa aaggaacacu accauuccca caaagcagac ucagaccuuu acaaccuaca     1380

gcgacaacca aaguucugua cuuguucagg uguaugaagg agagcgggca augacuaaag     1440

acaauaaccu guuggguaag uucgaucuaa cgggcauacc uccagcuccc cgaggggucc     1500

cucagaucga agugacauuu gacauugaug ccaauggaau ccugaacguc accgccgcag     1560

acaaauccac uggcaaggag aauaagauca ccauuacaaa cgauaaaggu cgccucagca     1620

aggacgauau agacagaaug gugcaggagg cggaaaggua caaaucggag gaugaagcua     1680

aucgggaccg cguugccgca aagaacgccc uggagucuua uaccuacaau aucaaacaaa     1740

cuguggagga ugaaaaacuu agagggaaga uuuccgagca ggacaagaac aagauccugg     1800

auaaauguca ggaaguaauu aauugguugg acaggaacca gauggcugag aaggacgaau     1860

augagcacaa acaaaaggag cucgaacgug ucugcaaucc aaucauauca aaacuguacc     1920

agggcggacc cggcggggga agugguggcg ggggaagcgg cgccuccggu gggccgacaa     1980

ucgaggaagu ggauugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  6553
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt3)

<400>  6553
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccag uccugcuacg      120

uugccguggc uagagcagga gguauugaga ccauagccaa cgaauauucu gauaggugua      180

cacccgcgug caucucauuu ggcccuaaga aucggaguau uggggcugcc gcaaaaagcc      240

aaguaaucuc caacgccaag aauacugugc agggauucaa acgcuuucac ggccgagcuu      300

ucucugaccc auuugucgag gcagaaaagu cgaaccucgc cuacgauauu gugcagcuuc      360

cgacgggucu gaccgggauc aaaguuacau auauggagga agaacguaau uucacuaccg      420

aacaggugac agcuauguug uuaucaaagc ugaaggaaac cgccgagagc guccucaaaa      480

agcccguggu agacuguguu gugagugucc cuugcuuuua cacugaugcg gaaagaaggu      540

ccgugaugga cgcaacacaa auagccggac uaaacugucu gcggcuuaug aaugagacca      600

cggcuguggc ccuggcauau ggcaucuaca aacaggauuu gccagcucuc gaggaaaagc      660

cccgcaacgu cguuuucgug gacaugggcc auucugccua ucagguaagc gugugcgcgu      720

uuaauagagg gaaacugaag guccuggcca cugcauucga uaccacacuc ggagguagga      780

aguuugacga gguguuaguu aaccacuucu gugaagaguu uggcaaaaag uacaaacugg      840

auauuaaguc caaaauccgg gcucuuuugc gccugucaca ggaaugcgag aagcucaaaa      900

agcuaaugag ugccaaugcu agcgaccugc cucuuucuau ugaguguuuc augaacgaug      960

uggacgucuc cgggacuaug aaucgaggaa aguuccugga aaugugcaac gacuugcucg     1020

ccagagugga gccaccccug aggucaguau uagaacaaac caaacugaag aaagaggaua     1080

ucuacgcagu ugaaauagug ggcggugcca cacggauucc ugcugucaag gagaaaauca     1140

gcaaguuuuu cgggaaggag cucaguacca cgcuuaaugc ggacgaagca gugacucgug     1200

gaugugcccu gcagugcgcu auuuugucuc cagccuuuaa aguccgcgag uucuccauca     1260

cagauguggu uccguauccc aucagccuaa gauggaacuc gccugcagaa gaggggucuu     1320

ccgacugcga aguguuuuca aagaaccaug ccgcuccauu caguaaagua cugaccuuuu     1380

acaggaagga gcccuucacu cucgaggccu auuacagcuc cccucaggau cugccauauc     1440

ccgacccggc aauugcgcag uuuucugucc aaaaagugac accucagagc gauggcucaa     1500

guuccaaggu uaaggugaaa guccggguga auguacacgg cauauucagc gugucuucag     1560

cuagucuugu ugaaguccau aagagcgagg aaaacgagga gcccauggaa accgaccaga     1620

augccaaaga ggaagagaag augcaagugg aucaggagga gccacacgug gaggaacagc     1680

agcaacagac gccugcagag aacaaagccg aauccgagga aauggagacc ucucaggcug     1740

gaucgaagga caagaaaaug gaucagcccc cacaagccaa gaaagcaaag gucaaaacaa     1800

gcacuguuga ccugcccauc gagaaucagu ugcucuggca gauugaccga gaaaugcuga     1860

acuuauacau cgagaaugaa gguaagauga uaaugcagga uaaacuggag aaggaacgca     1920

acgacgcuaa gaaugccgug gaggaguaug uguacgaaau gagagauaaa cuauccggcg     1980

aguacgaaaa guuuguauca gaggacgaua ggaacaguuu cacccucaaa cuggaggaca     2040

cagaaaauug gcuuuaugag gauggggaag accaaccuaa gcaggucuac guggauaaau     2100

uggcggagcu gaagaaccuc ggacagccaa uuaagauccg guuucaggaa ucugaggagc     2160

gcccgaaacu guucgaggag cuuggcaagc aaauccagca guauaugaaa auuaucagcu     2220

ccuucaagaa uaaagaagac caauacgauc accuggacgc cgcugauaug acuaagguug     2280

agaagucaac caacgaagca auggagugga ugaauaacaa auugaaccuc cagaauaagc     2340

agagccugac aauggacccc guggucaaau cuaaggagau ugaagccaaa auaaaggagu     2400

uaaccuccac uuguaguccu aucauuagca agccaaaacc caagguggaa ccuccaaaag     2460

aggaacagaa gaacgcugag caaaaugguc ccguugacgg gcagggcgau aacccgggac     2520

cucaggccgc agagcagggc acggacacag cggugccauc ugauuccgac aaaaagcugc     2580

ccgaaaugga uaucgacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  6554
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt3)

<400>  6554
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccuc aacugcuaca      120

uugccguugc uagauccgga gguauagaga ccaucgcaaa ugaauauucu gauaggugua      180

cacccgccug cauuucacuu ggcagucgga cucgcgcgau cgggaacgcu gccaagagcc      240

agauugugac gaauguacga aacaccaucc acggauuuaa aaagcugcau ggccguuccu      300

ucgacgaucc uauagugcaa acagagagaa ucagguugcc auacgaauua cagaaaaugc      360

cgaaugguuc ugcagggguc aaggugcggu aucuggagga agagagaccc uuugccauug      420

agcagguuac uggaaugcua cucgcuaaac ugaaggaaac cucggagaac gcacuuaaga      480

aaccuguggc cgacuguguc aucucaauuc ccagcuucuu uacagaugcu gaaagaagga      540

gugugauggc cgcggcacag guagccggcc ugaauugcuu gcggcucaug aacgagacca      600

cugcuguugc ccuggcauac ggcaucuaua agcaagaccu gccaccucuc gaugagaaac      660

cacgcaaugu ggucuucaua gacauggggc acuccgcuua ccagguguua gugugugccu      720

uuaacaaggg aaaacugaag guccuugcga caaccuucga ucccuauuug gguggccgaa      780

auuuugacga agcccugguu gauuacuucu gcgacgaguu uaagacgaaa uacaagauua      840

acgugaaaga aaauucuaga gcacuacuca ggcuguauca ggagugugaa aaacuuaaga      900

agcugaugag cgcuaacgcc uccgauuugc cucucaauau cgagugcuuc augaacgacc      960

uggacguauc aaguaaaaug aaccgggcuc aguuugagca auuaugugcc agccugcucg     1020

cacgugugga accaccgcuu aaggccguca uggagcaggc uaaucugcag cgcgaagaua     1080

uuucuuccau cgagaucguu gggggagcga cucgcauucc cgcagugaag gaacagauaa     1140

ccaaauucuu cuugaaggac aucucaacaa cucuaaacgc cgaugaggcu guggccaggg     1200

gcugcgcacu gcaaugugcc auucucagcc cugcuuuuaa aguccgggag uucaguauca     1260

ccgaccuggu gccauacucu auaacacuuc gauggaagac cuccuuugaa gaugguagcg     1320

gggagugcga aguauucugc aaaaaucauc ccgccccuuu uucgaagguu auuacguucc     1380

acaagaaaga gccauuugaa cuggaggcau ucuauacuaa cuugcaugag gugcccuacc     1440

cggacgcgcg caucggaucu uuuacaaucc agaaugucuu cccucagucc gauggcgacu     1500

caaguaaggu gaaagucaag gugagaguua acauucacgg caucuuuagc guggcuuccg     1560

ccucuguaau ugaaaaacaa aaucucgagg gggaucacag cgacgcaccc auggaaaccg     1620

agacuucauu caagaacgag aauaaggaua acauggacaa aaugcagguc gaccaggaag     1680

agggacauca gaagugucac gccgaacaua caccagagga agagauagau cacaccggug     1740

cuaaaacgaa gagugccgug uccgacaaac aagauaggcu gaaucagacc uuaaagaagg     1800

gcaaaguuaa gagcaucgac cugccuauuc agucuucacu augccggcag cucgggcaag     1860

aucugcuuaa caguuauauc gagaaugaag gaaaaaugau caugcaggac aaguuggaga     1920

aagaacgcaa cgaugcaaag aaugcugugg aggaauacgu cuaugacuuu agagauaggc     1980

ugggcacagu guacgagaaa uucauuacuc ccgaggaccu cagcaagcug uccgccguac     2040

uugaagauac cgagaacugg cuguacgaag acggugagga ucagccaaaa cagguguaug     2100

uugacaaguu gcaagaacuc aagaaauacg ggcagcccau acagaugaag uauauggagc     2160

acgaggaacg uccuaaagcg cugaacgacu uaggcaagaa gauccagcug gucaugaaag     2220

ugauugaggc cuaccggaau aaggaugaac gauaugacca ucuagaucca acagagaugg     2280

agaaagugga aaaguguauc ucugacgcua ugucguggcu caacagcaaa augaaugcac     2340

aaaacaagcu gucccuuacu caggauccgg ucguuaaggu gucagagauu guggccaaaa     2400

guaaggaauu ggacaauuuc ugcaacccca ucauauacaa accuaagcca aaagcugagg     2460

uacccgaaga uaagccuaag gccaauucug agcacaacgg accaauggac ggccagagcg     2520

ggaccgagac aaaauccgau ucaaccaagg acagcucuca acauacuaaa uccaguggag     2580

aaauggaggu cgauugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  6555
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt3)

<400>  6555
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugagcc ucguggccgc uaugcuucug uuguuauccg      120

cagccagagc ggaggaagag gacaaaaagg aagaugucgg caccguugug gggaucgacc      180

ugggaacaac uuacucuugc guaggugugu ucaaaaacgg cagggucgag auuauagcua      240

augaucaggg gaaccggauc acgcccucau auguggccuu uaccccugaa ggagagcgcc      300

uaauuggcga cgcagccaag aaucaacuca caaguaaccc agagaauacu guuuucgaug      360

cuaaacgacu gaucggucgu accuggaacg acccgagcgu gcagcaggau auuaaguuuc      420

uucccuucaa ggucguggaa aagaagacaa aaccuuacau ccagguagac auagggggag      480

gccaaaccaa gacuuuugca ccagaggaaa ucuccgccau gguucugaca aaaaugaagg      540

agaccgcuga ggccuauuug ggcaagaaag ugacgcacgc ggucgugacu gugcccgcau      600

acuucaauga ugcccagaga caggcuacca aggacgccgg gacaauugca ggacucaacg      660

ucaugaggau cauuaaugaa ccuacugcug ccgcgaucgc cuauggucug gauaaacggg      720

agggcgaaaa gaacauacug guuuuugacc ucgggggagg caccuucgau gugucuuuac      780

ugacaauuga caauggugua uuugaggugg ucgcaaccaa cggggacacg caucuuggag      840

gcgaagauuu cgaccagcgc gugauggagc acuuuaucaa auuguacaag aaaaagacug      900

gcaaggaugu uagaaaagac aauagggcug ugcaaaagcu gcggcgcgag gucgaaaaag      960

ccaagcgagc ucuaucguca cagcaucagg ccagaauuga gaucgaaucu uucuaugagg     1020

gggaagauuu uagugagaca cucaccaggg caaaauucga ggaacugaac auggaccuuu     1080

uccgguccac uaugaagcca gugcagaagg uacuggagga uucugacuug aaaaagagcg     1140

auaucgacga aauuguucuc gugggagguu ccacacguau acccaaaauc caacagcugg     1200

ucaaggaguu uuucaauggc aaagaaccuu cacgcgggau uaacccagau gaggccgugg     1260

cuuacggagc ggcaguccag gccggcgugu uaagugguga ccaagacacc ggggaucugg     1320

uucuccuuga cguguguccg cugacguugg gcaucgagac cguaggaggc gucaugacaa     1380

agcuaauacc cagaaacacu gugguuccua ccaagaaaag ccagauuuuu agcacagcuu     1440

ccgauaauca gccaacugug accaucaagg ucuacgaagg ggagaggccc cugacaaaag     1500

acaaccaccu ccugggaacc uucgaucuua cugguauccc uccagcaccc cggggcgugc     1560

cgcagauuga aguaacguuu gagaucgacg ugaaugggau ucugcgaguu acagccgagg     1620

auaagggaac cggcaacaaa aauaagauaa cuaucaccaa cgaccaaaau cgcuugacac     1680

cugaagagau ugaaagaaug gucaacgaug ccgagaaguu cgcugaagag gacaaaaagc     1740

ucaaagagag gaucgauacc cggaaugaac uggagucaua ugccuacagc uuaaagaacc     1800

agaucgguga caaagaaaag cuagggggca aacugaguuc ugaggauaag gaaacuaugg     1860

agaaggcagu ggaggagaaa auugaauggc ucgaauccca ucaggacgcg gacauagagg     1920

auuuuaaggc uaaaaagaaa gaacuggagg agaucgugca gcccauuauc agcaaacuuu     1980

auggaucggc cggcccaccu cccacagggg aagaggacac ggcagaaaag gaugaguugu     2040

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  6556
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt3)

<400>  6556
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gagagcuggc ugugggcauc gaccucggga      120

ccacauacag cugcgucgga guuuuccaac aggguagggu ggaaauucuu gcaaacgauc      180

agggcaaucg gacuacgccu uccuauguag ccuuuaccga cacagagcgc cugguggggg      240

augcggcuaa gucucaggcc gcauugaacc cacacaauac ugucuucgac gccaaacgau      300

uaauaggacg uaaguuugcu gauaccacag ugcaaucaga caugaaacau uggccguuca      360

gaguugugag ugaaggcggu aagcccaaag ucagggugug uuaccgcggg gaggauaaga      420

ccuuuuaucc ugaagagauc agcuccaugg uacugucuaa gaugaaagag acugcagaag      480

ccuaccuagg acagccaguu aagcacgcug ugauuacagu ccccgccuau uucaacgacu      540

cgcagcggca ggcgaccaaa gaugcaggcg ccaucgcugg ccucaaugug cugagaauua      600

ucaacgagcc uacggccgca gcuauagccu acgggcuuga caggcgggga gcgggugaac      660

gcaaugugcu gaucuuugau uugggcgggg gaacuuucga cgucucaguu cucagcauug      720

augccggcgu guuugaggua aaggcaaccg cuggugacac acaucucggg ggagaggacu      780

ucgauaaccg acuggugaau cacuuuaugg aagaguucag aaggaaacau ggcaaggacc      840

ugaguggcaa caagcgggcc uuacgucgcc ugagaacugc uugcgaaagg gccaaacgga      900

cccuuuccuc uagcacacaa gcaaccuugg agaucgauuc ccuguuugaa ggggucgacu      960

ucuauacguc aauuacucga gcccgcuucg aggagcuaug uagugaucuc uuuagaagca     1020

cacuggaacc aguggagaag gcucuuaggg acgcgaaacu ggauaaggca cagauccacg     1080

acguuguguu ggucggaggu ucuacccgga uacccaaagu gcagaagcuc cugcaggauu     1140

ucuuuaaugg caaagaauua aacaagucca uuaauccuga cgaggccgua gcuuacgggg     1200

ccgcaguuca agccgcugug cugaugggag auaagugcga aaaaguccag gaccuccuuc     1260

uguuggacgu ggccccacua ucacugggcc ucgagacugc cggugggguc augacaaccc     1320

ugauccagcg caacgcgacg auuccgacca agcaaacaca gacuuucacc acauacagcg     1380

auaaucagcc cggcguguuu auccagguuu augagggaga aagagcuaug acuaaagaca     1440

acaaccuucu gggcagguuc gaguugagug ggaucccucc agcaccccgu ggagugccuc     1500

aaauugaagu aaccuuugau auagacgcaa augguauccu cucugucaca gccaccgauc     1560

gguccacugg caaggcuaac aaaauuacga ucacaaauga caaggggcga cugagcaagg     1620

aggaagugga gagaaugguu cacgaggccg aacaguacaa agcagaggau gaagcucaga     1680

gggaccgcgu ggccgcgaag aacucguuag aggcccaugu cuuccacgug aaaggaucuc     1740

ugcaggagga aucccuacgg gauaagauac cagaggaaga cagaaggaaa augcaagaua     1800

agugucgcga gguacucgcu uggcuggaac auaaucagcu ugcagagaag gaggaauaug     1860

agcaccagaa acgagaauug gagcagauuu gccggcccau cuuuucacgu cuguacggcg     1920

guccgggggu gccuggcgga aguagcugug gcacccaagc cagacagggg gaccccucca     1980

cuggaccaau cauugaagag guugauugag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  6557
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt3)

<400>  6557
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gagagcuggc ugugggcauc gaccucggga      120

ccacauacag cugcgucgga guuuuccaac aggguagggu ggaaauucuu gcaaacgauc      180

agggcaaucg gacuacgccu uccuauguag ccuuuaccga cacagagcgc cugguggggg      240

augcggcuaa gucucaggcc gcauugaacc cacacaauac ugucuucgac gccaaacgau      300

uaauaggacg uaaguuugcu gauaccacag ugcaaucaga caugaaacau uggccguucc      360

agguugugag ugaaggcggu aagcccaaag ucagagugug uuacagggga gaggauaaga      420

ccuuuuaucc ugaagagauc agcuccaugg uacugucuaa gaugaaagag acugcagaag      480

ccuaccuagg gcagccaguu aagcacgcug ugauuacagu ccccaccuau uucucgaacu      540

cacagcggca agccacgaaa gacgcgggcg caaucgccgg ccucaaggug cugccuauua      600

ucaaugaggc uacugccgca gcuauagccu acgggcuuga ucgcagagga gcggguaaaa      660

ggaacgugcu gaucuuugac uugggcgggg gaaccuucga ugucagcguu cucaguauug      720

acgccggcgu guuugaagua aaggcaacag cuggugauac ucaucuuggg ggagaggacu      780

ucgacaaucg gcuggugaac cacuuuaugg aggaguuccg ccgaaagcau ggcaaagauc      840

ucuccggcaa uaagagagcc uuaaggcggc ugcguaccgc uugcgagcgc gccaaaagaa      900

caccaucuag cuccacccag gcaacgcuug aaaucgacuc auuguuugag ggggucgauu      960

ucuauaagag uauuacuagg gcccgguucg aagaacugug uagcgaccua uuucgaucua     1020

cacucgagcc cguggaaaaa gcucugcgcg augcgaagcu ggacaaagca cagauccacg     1080

auuucguucu gggagguggc uugcacuccc auccucaggg ggccgaggug gcugccggac     1140

uccugcaaag acagggcgca gaacaggagc accaaccaug aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  6558
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt3)

<400>  6558
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaagggcc ccgccguggg gaucgaccug ggaaccacau      120

acuccugcgu cgguguuuuc cagcacggca aaguggagau uauagcuaac gaucaaggga      180

auagaacuac gccuucuuau guagcauuua ccgacacaga aaggcucauc ggagaugccg      240

cgaagaacca gguggcuaug aauccaacua acaccgucuu cgacgccaaa cggcuuauug      300

gccgccgauu ugaugacgca gugguucagu cagauaugaa gcauuggccg uucauggugg      360

ucaaugacgc cggucguccc aaagugcagg uagaguacaa gggggaaaca aagaguuuuu      420

auccugagga aguuagcucc auggugcuga ccaaaaugaa ggagaucgcu gaggcauacu      480

ugggaaaaac ugucacaaac gccgugguga ccgucccagc uuauuucaau gauucucaaa      540

gacaggccac gaaggacgcg ggcacuauug caggcuuaaa cguucugagg aucauaaaug      600

aacccaccgc cgcugccauc gcauacgggc uagauaaaaa ggugggagcu gagcggaacg      660

uacucauuuu ugaccugggu ggcgggacau ucgauguguc gauccuuacu auugaagacg      720

gaaucuuuga ggucaaguca accgccggcg acacacaccu ggguggggag gauuucgaca      780

aucgcauggu gaaccauuuu auagcggaau uuaaaagaaa gcacaaaaag gauauuagcg      840

agaauaaaag ggccguucgg cgcuugcgaa ccgcauguga aagagcuaag aggacgcuca      900

guuccucuac ucaggccagc aucgagauug acucccugua ugaaggaauc gauuuuuaca      960

caucaaucac ccgggcucgu uucgaggagc ugaacgccga ccucuuccgc ggcacuuuag     1020

auccugugga aaaagcacug agagacgcca aacuugauaa gagucagauu caugacauag     1080

ucuugguggg cgggagcaca aggaucccaa agauucaaaa gcugcuacag gauuucuuca     1140

auggaaaaga gcucaacaag ucuaucaacc ccgacgaagc uguagcguac ggugcagccg     1200

uucaggcugc cauacugucc ggcgacaaau cagagaaugu gcaggaucuu cuguugcucg     1260

acgucacccc ucugagcuua gggauugaaa cggcaggagg cgugaugacc guccugauca     1320

agcggaacac aacuauccca accaagcaaa cacagacuuu uaccacauau agugauaauc     1380

agccgggugu gcucauucaa guuuacgagg gggagcgagc caugaccaaa gacaacaauc     1440

uucugggcaa guucgaauug acuggaaucc cucccgcucc acgcggcgug ccccagauug     1500

agguaacguu ugauauagac gccaacggga uccuaaaugu cucugcagug gauaaaucca     1560

caggaaagga aaacaaaauu accaucacua augacaaggg uagacugagc aaggaggaua     1620

ucgaaaggau gguucaggag gcggagaaau auaaggcuga agacgagaaa cagcgggaua     1680

aggugucguc uaaaaacucc cucgaaucau acgccuucaa uaugaaggca accgucgagg     1740

acgagaagcu gcaaggcaaa auuaacgaug aagacaagca gaaaauacuu gacaagugca     1800

augagaucau uaacuggcug gauaaaaauc agacagccga aaaggaggaa uuugagcacc     1860

agcaaaaaga guuggaaaag guguguaacc cuaucauuac caagcucuau cagagugcug     1920

ggggaaugcc aggcgguaug cccgggggcu ucccgggagg cggggccccu cccagcggag     1980

gugcauccuc uggcccaacu aucgaggaag uagacugagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  6559
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt3)

<400>  6559
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucagcgccu ccagagcugc agccgcgagg cuggugggcg      120

cugccgcauc ucgggggccc accgccgcuc gccaccagga cucauggaac ggacucaguc      180

augaggcauu ccgacuuguc agccguagag auuacgccuc cgaagcuauu aagggugccg      240

uugugggcau agaccugggg acaacuaauu cuugcguagc ggugauggag ggaaaacaag      300

caaaggucuu ggaaaacgcc gagggcgcua ggacgacccc uucggugguu gccuuuacag      360

cagaugguga acgguuagug gggaugccag cuaaacgcca ggccgucacu aauccgaaca      420

auaccuucua ugcgacaaag agacugaucg gaaggcggua cgacgauccc gaggugcaga      480

aagacauuaa gaacguaccu uuuaagaucg uucgcgccuc aaauggcgau gcaugggugg      540

aggcucacgg caaacuauau agcccaaguc agauuggggc cuucguccuc augaagauga      600

aagaaaccgc ugagaacuac cugggacaua cugccaagaa ugcagugauc acagugcccg      660

ccuauuuuaa cgacucccaa cgacaggcua ccaaagaugc gggucagaua ucuggccuua      720

auguccugag aguuaucaac gaaccuacgg cagccgcuuu ggccuacggg cucgacaaga      780

gcgaggauaa ggugauugca guauaugacc ugggaggcgg uacuuucgau aucuccauuc      840

uggagaucca gaaaggggug uuugaaguca agucaaccaa uggagacaca uuccucggcg      900

gcgaggacuu ugaucaagcc uuacugaggc acauagugaa agaguucaag cgggaaacug      960

ggguugaccu uaccaaagau aacauggcuu ugcagcgugu gcgcgaagcc gcagagaagg     1020

cgaaauguga gcugaguagc ucuguccaga cagacauuaa ucuaccauac cucaccaugg     1080

auuccucagg acccaagcau cugaacauga aguugacgag agcucaguuu gaagguaucg     1140

ugacugaccu gauuaggcgg acaaucgccc cuugccaaaa agcaaugcag gaugccgagg     1200

uaagcaagag ugacaucggc gaaguuauuu uggucggggg aaugacccga augccaaaag     1260

ugcagcaaac ugugcaggau cucuucggcc gcgcuccguc uaaggccguc aaccccgacg     1320

aggcaguggc uauaggugcc gcgauccaag ggggcguucu ggccggagau gugacagacg     1380

uauuacugcu cgacgucacc ccucuuuccc ugggcauuga aacgcuuggg ggaguguuua     1440

ccaaacuaau caauagaaac acaacuauac caaccaaaaa gagccagguu uucucgacag     1500

cugcagaugg ucagacucag guggagauua aggucuguca gggcgagagg gaaauggccg     1560

gggacaauaa gcugcucgga caguucaccc ugaucggcau ucccccugcu ccacggggug     1620

ugccccaaau cgagguaaca uuugauaucg acgccaacgg gauugugcac guuucugcaa     1680

aagauaaggg caccggacgc gaacagcaga uagucaucca guccucaggc gggcuuagua     1740

aagacgauau ugagaauaug gugaagaacg cggaaaagua cgccgaggag gacagaagga     1800

aaaaggaacg uguggaggcu gucaauaugg ccgaaggaau cauccacgau acugagacga     1860

aaauggagga guucaaggac caacugccgg cagaugaaug caacaaauug aaggaagaga     1920

uuagcaagau gcgggaacuc cuggcucgaa aagacuccga gacaggugag aauauaagac     1980

aggccgcauc uagcuuacag caggccucac ugaagcuauu ugaaauggcu uauaaaaaga     2040

uggcgaguga gagggaaggc uccgggagcu cuggaaccgg cgagcaaaaa gaagaucaga     2100

aggaggagaa acagugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  6560
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt3)

<400>  6560
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg aggcuggcgg gagcgaugga cccagagaaa      120

ccgcaccuac auccgccuac ucuucaccag cgaggagucu gggugacacu ggcaucacgc      180

cgcucagccc cucccacauu gugaacgaua ccgacucuaa ugucucggag cagcaaucau      240

uccuuguugu gguagcugug gauuuuggga caacuagcag uggauaugcc uacuccuuca      300

ccaaagaacc ugagugcaua caugucaugc ggcgcuggga aggcggugac ccaggggugu      360

cuaaccagaa gacacccacc acuauccugu ugacaccuga gcgaaaauuu cacagcuucg      420

gauaugcagc ccgugauuuu uaccaugacu uagauccaaa ugaggcuaag caguggcugu      480

aucuagaaaa auucaagaug aagcuccaca ccacgggcga ccugacuaug gauaccgacc      540

uuacagcagc caacggcaaa aagguuaaag cucuggagau uuuugccuac gcguugcagu      600

auuucaagga acaagcacuc aaagagcugu ccgaucaggc cgggucagag uuugaaaaua      660

gugacgugag augggucauc acugugcccg cuauuuggaa gcagccugcc aagcaguuca      720

ugaggcaagc agcuuaccag gccggacugg cgagcccaga gaacucugaa cagcucauca      780

uagccuuaga gccggaagca gcuuccaucu acugucggaa acugcgccuu caucagauga      840

uugaguuguc aagcaaggcc gcuguaaaug guuauagugg cucugacacc guuggggccg      900

gauuuacaca agcaaaagag cacaucagaa ggaaccggca gucccgcacc uuccuggugg      960

aaaaugucau uggcgagauc uggagcgaac uagaggaagg ugauaaguac gugguggucg     1020

acuccggggg aggcacgguu gaucucacug ugcaccagau acgacugccc gagggccauc     1080

uuaaagagcu guauaaggcc acagggggac cuuacgguuc uuugggcgua gacuaugaau     1140

uugagaaacu ccuguacaag auuuucgggg aagauuucau cgagcaauuu aagauuaaaa     1200

gaccagcugc guggguggac uuaaugaucg cauucgaauc caggaagcgg gccgcugccc     1260

ccgaucguac caacccucug aauaucacuc ucccauuuuc auucauugac uauuacaaaa     1320

aguuucgcgg acacaguguc gagcaugcac uuagaaaaag caacguggau uucguuaagu     1380

gguccucuca gggcaugcug aggaugagcc ccgacgccau gaaugcuuug uuuaagccga     1440

caauagauuc aaucauugag caccuacggg accuguucca gaaaccugaa gugaguaccg     1500

ucaaguuucu cuuccuggug gguggguuug ccgaggcacc ccuucugcag caagcgguac     1560

aggcugccuu cggcgaccag ugccgaauca uaauuccaca ggauguugga uugacgaucc     1620

ucaaaggcgc agugcuguuu ggguuagacc cugccgucau caaggugcgc agaucgcccc     1680

ugaccuacgg agucggugug cuaaacaggu auguugaagg caaacaccca cccgagaagc     1740

uccuggugaa ggaugggaca cgguggugua cugacguauu cgauaaauuc auuagcgcug     1800

accaaucugu cgcccuugga gaguugguga agcgcucaua caccccugca aaaccaaguc     1860

agcugguuau cgugauuaau auauauagcu ccgaacauga uaacgucucu uuuaucacag     1920

acccgggcgu gaagaaaugc gguacucuca gacuggaucu uaccgggaca ucgggcaccg     1980

cuguacccgc caggcgugag auucagacuc ugaugcaguu cggagacacg gaaaucaagg     2040

cgacagccau cgauauugcu accagcaagu ccgugaaagu uggcauagac uuuuugaacu     2100

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  6561
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt3)

<400>  6561
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuggccgugc ccgagauggg ccuccagggg cuuuacaucg      120

gaagcucccc ugaaagaucu ccagucccgu cacccccugg uaguccaagg acccaagaga      180

gcugcggcau ugcuccccug acaccuuccc agucuccaaa gcccgaaguu cgggcaccuc      240

agcaggccuc guucucagug guaguggcga uagacuuugg gacuacgagc aguggauaug      300

cuuucuccuu ugccucugau ccagaggcaa uccacaugau gcgcaaaugg gaaggcggug      360

acccgggggu cgcccaccaa aagaccccca cauguuuguu acugacuccu gagggagcuu      420

uccacagcuu uggcuacacc gcacgagauu auuaccauga ccuagaucca gaggaagccc      480

gugacuggcu cuauuucgag aaauuuaaga ugaaaauuca cuccgcuaca gaucugaccc      540

uuaagacuca gcuggaagcc gugaacggca agacaaugcc cgcguuggag guuuucgcac      600

augcccucag auuuuucagg gagcacgcuc ugcaggaacu gcgggagcag ucaccuaguc      660

ucccagaaaa agacaccgug cgcugggucu uaacggugcc cgccaucugg aagcaaccgg      720

caaaacaguu uaugagagag gcugccuacc uggcggggcu uguaagcagg gaaaaugccg      780

agcaguugcu gauugcacua gagccugaag cugccucugu uuauugccgg aagcuccgcc      840

ugcaccagcu ucuggauuug uccggacgag cucccggugg cgggagacuc ggagagaggc      900

ggucaaucga cagcaguuuc cgucaagccc gcgaacagcu gagaaggucu cggcauuccc      960

gaaccuuuuu aguggagagc ggcgucggug aacugugggc agagaugcag gccggggauc     1020

gcuacguggu ggcugacugu ggaggcggca cugucgaucu cacaguucac caacuugagc     1080

agccacaugg gacucugaaa gaauuguaca aggcgucggg agguccuuau ggcgcagugg     1140

ggguagaccu agccuucgag cagcugcucu gcagaauauu cggagaagac uuuaucgcua     1200

ccuucaagag gcagcggccc gccgcauggg uggaucugac aauugccuuu gaggcucgca     1260

aaagaaccgc cggcccacac agggcgggug cacuuaacau cucucugccc uucuccuuua     1320

uugacuucua ccguaagcaa cgggggcaca augucgaaac ggcuuugcga agaucaagug     1380

ugaacuuugu uaaauggagc ucccagggca ugcucaggau gucuugugag gccaugaaug     1440

agcuguucca gccuacugug agcggaauca uacagcauau ugaagcauua cuggcccgcc     1500

cagaggucca aggcgugaag cuacucuuuc ugguaggggg auucgcugaa ucagccguuc     1560

uucagcacgc agugcaggcu gccuugggug cgcggggccu gagagucgug gucccgcaug     1620

auguggggcu cacaauccug aaaggagccg uucuuuuugg ccaggcuccc ggugugguaa     1680

ggguccgccg aaguccucug accuaugggg ugggcguuuu gaaccgguuc gugccaggac     1740

gucauccccc ugagaagcuc cuggucagag acggcaggcg cuggugcacu gauguguuug     1800

agcgguucgu agcagccgaa caauccgugg cuuuagggga ggaaguuaga aggagcuacu     1860

guccagcccg acccggacag cgccgggucc ugauuaaucu auauugcugu gcagcggagg     1920

acgccagauu caucacagau ccggguguga ggaaaugcgg cgcucucucu cuggaacuug     1980

agccugccga cugugggcag gauaccgcag gagcuccacc cggccgucgc gagauccggg     2040

ccgcaaugca guuuggugac acggaaauua aggugaccgc cgucgauguu ucaacaaaca     2100

gaagugugag ggcuagcaua gacuucuugu ccaauugagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  6562
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt3)

<400>  6562
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgggaga ugaccauccu gggcagcgcu gugcucacac      120

uucuguuggc aggguacuua gcccagcaau aucugccccu accuacucca aaggucauug      180

gaauagaccu cgguacgacc uacugcuccg uuggcguguu cuuuccgggg acaggaaaag      240

uaaaggugau ccccgaugaa aacggccaca uuucuauccc uucaaugguc aguuucacug      300

acaaugaugu guauguuggu uacgagagcg uggaacuggc ggacuccaac ccacagaaua      360

ccauuuauga ugcuaaaagg uuuaucggga agauauucac agccgaggaa cuugaggcag      420

agaucggacg guaccccuuu aaaguccuga acaagaaugg caugguggag uucucuguaa      480

ccucgaacga aacuauuaca guuucaccug aauauguggg cagccgcuug cuccugaagc      540

ugaaagagau ggccgaggcu uaccucggga ugccagucgc aaaugccgug aucagugugc      600

ccgcugaauu ugacuuaaag cagcgaaacu ccaccauuga ggccgcgaau cuggcaggac      660

uuaaaaucuu gcgugucaua aacgaaccua cggccgcugc cauggcauac ggucugcaua      720

aggcugaugu uuuccacgug cuaguaauug accucggcgg gggaacucug gaugugucuc      780

uucugaauaa acagggcggu auguuuuuga ccagagccau gagcgggaac aauaagcucg      840

gaggccaaga cuucaaccag aggcuguuac aguaucugua caagcagauc uaucaaacau      900

acggcuuugu cccaucccgg aaagaggaaa uucaucgccu cagacaggcg guggagaugg      960

uuaaguugaa ucugacuuug caccagucag cccagcuaag ugugcugcuc accgucgagg     1020

aacaagauag gaaagagccg cauagcucug acacagaacu gcccaaggau aaacuuuccu     1080

cagcagacga ccaccgggug aacagcgggu ucggacgcgg ucugagugau aagaaaucug     1140

gcgaguccca gguauuguuu gaaaccgaga ucagccgaaa acucuucgac acgcugaacg     1200

aggauuuauu ccagaagauc cugguuccua uucaacaggu gcuaaaggaa gggcaccucg     1260

agaagacuga aauagacgag gucgugcugg ucggaggcuc gacaagaauc ccaaggauua     1320

gacaggugau ccaggaauuu uucgguaaag aucccaauac cucuguugac ccugaucuug     1380

cugugguaac uggggucgcc auacaagcug gcauugacgg aggcuccugg ccacuucagg     1440

ugucagcccu ggagaucccc aacaagcauc uccagaaaac aaauuuuaac ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6563
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt3)

<400>  6563
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgcuaucg gcgugcaccu ggggugcacc agcgcaugug      120

ucgccguuua caaggacggu agagcgggag ugguagcuaa cgaugccggc gacaggguga      180

cacccgcagu cguggccuau uccgagaaug aagagauugu ugggcucgcu gcaaaacagu      240

cucggauacg caacaucuca aauacuguga ugaaggucaa acaaauucuu ggacgaagua      300

gcuccgaucc ucaggcccag aaguacaucg cugaaucuaa augccuggug auugagaaga      360

acggcaaguu gcguuaugaa aucgacacgg gugaggagac caaauucgua aauccagaag      420

auguugccag auuaauauuu ucgaagauga aagagacagc gcauucagug cuggggagcg      480

acgcaaacga ugucgugauc acugugccgu ucgacuuugg agaaaagcag aaaaaugccc      540

uaggcgaggc ugccagggca gcuggcuuca acguccuccg gcugauucac gagcccagug      600

ccgcgcuucu ggccuacggg aucggacaag auuccccuac cgguaagucu aauauuuugg      660

uuuuuaagcu cggcgggaca agccuguccc ugucagugau ggaaguaaac aguggaaucu      720

aucgcgugcu cagcaccaau acugacgaua acauaggcgg ugcacauuuc acagagaccu      780

uagcucagua ccuggccucu gaauuucaga gauccuucaa acacgacguc agggggaaug      840

cucgggccau gaugaagcug acgaacucag cagagguggc caaacauagc uugaguacuc      900

ugggaucugc uaauuguuuu cuagauuccc ucuaugaagg ccaggacuuc gacugcaacg      960

uuagccgcgc gcgauuugag cugcuuuguu cgccacuguu caacaagugc auugaggcaa     1020

ucagaggcuu gcucgaucaa aauggguuua ccgccgacga uauuaacaaa gugguccugu     1080

guggagguuc uuccaggauc cccaaguuac agcagcugau caaagaccuc uucccugcug     1140

uggaacuucu uaauucaauu ccacccgaug agguaauacc uaucggcgcc gcaauugaag     1200

ccgggaucuu gauaggaaag gagaaccuac ugguugaaga cagucucaug auugagugca     1260

gcgcucggga uauccuggug aagggcgucg acgaguccgg ugccucucgu uucacagugc     1320

uuuuuccaag cgggacuccg cugcccgcac gcagacagca caccuugcaa gcgccuggcu     1380

caaucaguuc cgucugucuc gaacuguacg agagcgaugg caaaaauucu gcuaaggaag     1440

agacaaaauu cgcccaggug guuuuacagg accuggauaa gaaagaaaac ggacuaaggg     1500

acauucucgc agugcugacc augaagcggg acgggucacu ucacguaacg ugcacugauc     1560

aagagacagg aaagugugag gccaucagua uugaaauagc uagcugagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  6564
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt3)

<400>  6564
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gccuggacgu ugggucccag ucuugcuaca      120

ucgccguggc uagagcagga gguauugaga ccauagccaa cgaguucuca gauaggugua      180

cacccagugu aaucagcuuu ggcuccaaga aucggacuau ugggguggcg gcuaaaaacc      240

aacagaucac gcacgccaau aacaccgucu cuaauuucaa gcgcuuucau ggacgagcau      300

ucaacgaccc uuuuauucag aaagagaagg aaaaucucuc guaugaucuu gugccacuga      360

aaaacggcgg uguugggauc aaggugaugu acaugggaga ggaacacuug uucucagucg      420

agcagauaac agccauguua cugacuaagc uaaaagagac cgcugaaaau agccucaaga      480

aaccggugac agacugcgua aucaguguuc ccuccuuuuu caccgaugca gagcguagau      540

cugugcugga cgccgcucaa auugucggcc uuaacugucu gagguugaug aaugauauga      600

cugccguggc gcucaacuau ggcaucuaca agcaggaccu gccuagccug gaugaaaaac      660

cacggauugu ggucuuuguu gacauggggc auuccgcauu ccagguguca gccugcgcuu      720

uuaauaaggg aaagcucaaa guauuaggua cagccuucga ucccuuucug ggcgggaaga      780

acuucgacga gaaacuugug gagcacuucu gugcagaauu uaagaccaaa uauaaguugg      840

augcuaaaag uaagauccgc gcccugcuaa gacucuacca ggagugcgaa aagcugaaaa      900

agcugaugag cucuaauucc acggaccuuc cuuugaacau agaguguuuc augaacgaca      960

aagaugucuc aggaaagaug aauaggagcc aauuugaaga acucugcgcg gagcuguuac     1020

agaaaauuga agugccacug uauagucucc uugagcagac ucaucugaag guugaagacg     1080

ugucugccgu cgagaucgug ggcggugcaa cccggauucc cgcuguaaag gaacgcaucg     1140

ccaaauucuu ugggaaggau aucuccacaa cuuugaacgc ugacgaggcc guugcacgag     1200

gaugugcccu acagugcgcu auucugagcc cugcguucaa agugagagag uuuucgguca     1260

ccgaugcagu gccauucccg auaucucuca ucuggaauca cgacuccgaa gauacagagg     1320

gcguccacga aguguuuuca aggaaccaug ccgcucccuu caguaagguu cugaccuuuc     1380

uucggcgugg cccuuucgag cuggaagccu uuuacagcga cccacaaggg gugcccuacc     1440

cugaggcaaa aauuggacgc uucguagucc agaauguguc cgcccagaag gauggugaga     1500

agucuagagu uaaagugaag gucaggguga acacgcacgg caucuucacu auaagcacag     1560

cuucaauggu agaaaaagug ccaaccgagg aaaaugagau gaguuccgag gccgacaugg     1620

aauguuugaa ccaacggccc ccggagaauc cugauacuga caagaacguu cagcaggaca     1680

auagcgaagc agggacacag ccccaagucc agaccgaugc gcagcagacg ucucaaucac     1740

caccuagucc cgagcucacc agcgaagaga acaaaauucc agacgcugau aaggccaaug     1800

agaagaaagu ggaccagccc ccugaagcaa agaaaccaaa gaucaaagug gucaacguug     1860

agcugccgau cgaagccaau uuaguguggc agcugggaaa ggaucuacuc aacauguaua     1920

uugagacaga aggcaaaaug aucaugcagg acaagcugga gaaggagcga aacgaugcua     1980

aaaaugccgu ggaagaguac guauaugaau uucgcgacaa acuuugcggu cccuacgaga     2040

aauucauuug cgaacaagau caucagaacu uuuugagacu gcucacugag accgaggacu     2100

ggcuguauga agagggggaa gaucaggcaa agcaggcuua cgucgacaaa cuugaggagc     2160

ugaugaagau aggcacaccu gugaagguua gguuccaaga agccgaggaa cggccaaaaa     2220

uguuugagga auugggacag cgccuccagc acuaugcgaa gaucgccgcu gauuucagaa     2280

auaaagacga gaaguacaac cacauugacg aguccgaaau gaaaaaggug gagaagucug     2340

ucaaugaagu gauggagugg augaacaaug uuaugaacgc acaagccaaa aagucgcugg     2400

aucaggaccc cgugguaagg gcucaggaaa ucaaaacuaa gaucaaagag uuaaauaaca     2460

ccugugagcc ugucgugaca cagccaaagc ccaagauuga aagcccgaaa cuggagcgua     2520

ccccuaaugg cccaaacaua gauaagaaag aagaggaccu agaagauaag aauaacuuug     2580

gggccgagcc cccucaucaa aauggagagu gcuaccccaa cgaaaagaac uccgugaaua     2640

uggaccucga uugaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  6565
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt3)

<400>  6565
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg ugagaaggca gcggccccgc cgacgugucu      120

gcugggcucu gguugcagug cuccuugccg aucuguuggc guuaagcgac acccuggcug      180

uaauguccgu ggaucuaggc ucugagucaa ugaaagucgc caucgugaag ccugggguuc      240

caauggaaau ugugcucaac aaagagagua gaaggaagac accggucaua gugacucuga      300

aagaaaauga gcgguucuuu ggagacagcg cagccuccau ggcuaucaag aaccccaagg      360

caacgcuucg cuacuuccaa caccuguugg guaaacaggc cgauaauccu cauguagcuc      420

ucuaucaggc cagauuucca gaacacgagc ugaccuucga cccccagagg caaacaguuc      480

auuuucagau uucuucgcag cugcaguucu caccugagga agugcucggc auggucuuaa      540

acuacagccg gagucuggcg gaggauuuug cagaacaacc aaucaaggac gccgugauua      600

cugugcccgu cuucuuuaau caggcugagc gccgagccgu ucuucaggca gcuagaaugg      660

ccggguugaa agugcugcag cuaaucaacg auaauaccgc gacagcccuc uccuauggag      720

uauucaggcg gaaggacaua aacaccacug cacaaaauau cauguuuuac gauaugggcu      780

cugguagcac aguguguacc auugucacgu aucagauggu gaaaacuaag gaggcuggga      840

ugcagccuca acugcagauc cguggaguug gcuucgaccg cacccuuggc gggcuggaaa      900

uggaguugag acucagggaa cggcuggccg gauuauuuaa cgagcagcga aagggucagc      960

gcgcuaaaga ugugagagaa aauccaaggg ccauggcaaa gcugcuccgg gaggccaacc     1020

gccuuaaaac aguccugucc gcuaaugcgg accacauggc acaaauugag ggcuugaugg     1080

acgaugugga cuucaaggcc aaaguaacua gaguugaguu cgaggaacua ugcgcugauc     1140

uguuugagag ggugccgggg cccguccagc aggcccucca gucagcagaa augagucugg     1200

acgagaucga gcaagugaua cuugucggag gcgccacccg ugugccucgg guucaggaag     1260

ugcuguugaa ggcuguaggu aaagaggaac ucgggaagaa cauuaaugcc gaugaggcag     1320

cggcuauggg agccgucuac caggcagccg cucugagcaa ggccuucaaa gugaagccau     1380

uuguugugcg agacgcaguc guguauccca ucuuaguaga guucacaaga gagguggagg     1440

aagaaccugg cauucauucu cugaaacaca acaagagggu ucuauuuucc cgcaugggcc     1500

cauaccccca gcggaaaguc aucaccuuca acagauacuc acacgauuuu aauuuccaua     1560

ucaacuaugg ggaccucgga uuucuggguc cggaagaucu uaggguguuc ggcagccaaa     1620

auuugacgac ugugaagcug aagggggucg gagacaguuu uaaaaaguac ccugauuaug     1680

agucuaaagg cauuaaggcu cacuucaacc ucgacgaguc cgguguucug agccuugacc     1740

gcguggaauc gguguuugag acacugguag aagauucugc cgaggaagag uccaccuuga     1800

cuaaacucgg gaauacaaua ucaagucugu ucggcggagg caccacgccc gacgcgaagg     1860

agaacgggac cgauacaguc caggaagagg aagagagccc agccgaagga uccaaggacg     1920

agccugguga acagguggaa uuaaaagagg aagcugaggc acccguugaa gauggcucuc     1980

agccaccccc uccagagccg aagggggacg ccacucccga gggagaaaaa gcuaccgaga     2040

aggaaaaugg cgauaaaagc gaggcccaaa agccuucaga gaaggcagaa gcggguccag     2100

aggggguggc ccccgcuccu gaaggcgaga aaaagcagaa accagcccga aagcggcgua     2160

uggucgaaga gaucggagug gagcugguug ugcuagaccu ccccgaucug ccggaagaca     2220

aacuugcaca gaguguacaa aaguugcagg aucugacacu cagagaccug gagaaacagg     2280

aaagggagaa ggcugccaac uccuuagaag cauucauuuu ugagacucag gauaagcugu     2340

accaaccuga guaucaggaa gucagcaccg aggaacagcg cgaggaaauc ucuggcaaac     2400

uuucagccgc uaguacaugg uuggaggacg aggggguggg agcgaccacu gugaugcuca     2460

aggaaaaacu ggccgagcua cggaagcugu gucagggucu cuucuuuaga gucgaagaga     2520

ggaaaaagug gccagagcga cugagcgcac uugacaauuu gcugaaccau uccucuaugu     2580

ucuuaaaggg cgcucgccuc auacccgaaa uggaucaaau uuuuacggag guugaaauga     2640

caacccugga gaaagugauc aaugaaacuu gggccuggaa gaacgccacc cuugcugagc     2700

aggcaaaacu gccugccaca gagaagcccg uauugcucuc gaaagacauc gaagcgaaga     2760

ugauggcucu ggaucgggag gugcaguacc uacugaauaa ggccaaauuc accaagccaa     2820

gaccuaggcc caaagacaag aacgggacuc gugcagaacc accgcucaau gccagcgcuu     2880

ccgaucaggg agagaaaguc auuccucccg caggccaaac agaagacgcc gagccaaucu     2940

cagagcccga aaagguggag acggguagug aaccugggga uaccgagcca cuggaacuug     3000

gcggacccgg cgcggagccu gagcagaagg aacagucuac ugggcaaaaa cgcccguuga     3060

agaacgacga gcugugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6566
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt3)

<400>  6566
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaaa cccagacaca agaccagccu auggaggaag      120

aggaagugga gacuuucgcc uuucaggcug agaucgcaca gcugaugagc cucauuauaa      180

acacguucua cuccaauaag gaaaucuuuc uuagagagcu gauuucuaac ucaagugaug      240

ccuuggacaa aaucagguau gagagcuuaa ccgauccauc caagcuggac ucuggcaaag      300

agcuacacau uaaucucauc ccgaacaagc aagaucggac acugacuaua gucgacaccg      360

ggaucggaau gacaaaagcg gaucuuauua auaaccuggg uaccaucgcu aagucgggca      420

cuaaggccuu cauggaggca uugcaggccg gggcugacau uucaaugauc ggacaguuug      480

gcguugguuu cuacagcgca uaucucgugg ccgaaaaagu aacagugaua accaagcaua      540

augaugacga gcaguacgcu ugggaaaguu ccgccggggg aucuuuuacg guccgcacug      600

auaccggcga gcccaugggc cgagggacaa aagugauucu gcaccugaag gaagaccaaa      660

cugaguaucu cgaggaacgu agaaucaaag agauuguuaa gaagcauagc caguucaucg      720

gauacccuau caccuuauuu guggaaaaag agagggauaa ggaagucucc gacgacgagg      780

cggaggaaaa agaggauaag gaagaggaaa aagagaagga ggaaaaagag ucagaagaca      840

agccagagau ugaggaugug gguagugacg aagaggaaga gaagaaagau ggcgacaaga      900

aaaagaaaaa gaagauaaaa gaaaaguaua ucgaucagga ggagcugaac aaaacaaagc      960

ccauuuggac ccggaauccu gacgauauca cgaacgaaga guacggggag uucuacaaaa     1020

gccuuacuaa ugacugggaa gaucacuugg caguaaagca uuuuucuguu gaaggacagc     1080

uggaguuccg cgcccuacuc uuugugccaa gaagggcucc cuucgaccug uucgagaacc     1140

ggaagaaaaa gaauaacaua aaacuuuaug uccgccgagu guuuauuaug gacaauugcg     1200

aagaacugau cccugaauac uugaacuuca ucagaggcgu ggucgauucc gaggaccucc     1260

cacugaacau uucaagggaa auguuacaac agagcaagau ccugaaaguu auucggaaga     1320

aucucgugaa gaaaugucuu gagcuguuua cagaguuggc cgaagauaag gagaacuaua     1380

aaaaguucua cgaacaguuu aguaaaaaua uaaagcuagg uauccacgag gacucucaaa     1440

accguaaaaa gcuguccgag cuccugcgcu auuacaccag cgcaucgggg gaugaaaugg     1500

uaucucuuaa ggacuauugc acuagaauga aagagaauca gaagcacauu uacuacauca     1560

caggagaaac caaagaucag guggcuaacu ccgccuucgu cgagaggcug cggaagcaug     1620

gcuuggaagu gaucuauaug auugagccga uagacgagua cuguguucag caacucaaag     1680

aauuugaggg caagacgcug gugucaguca ccaaggaagg guuagagcug cccgaagaug     1740

aggaggagaa aaagaaacag gaagaaaaga aaacaaaguu cgagaaucua ugcaagauca     1800

ugaaagacau ucucgaaaag aaaguggaga agguaguugu gaguaaccga cuggucacua     1860

gcccuuguug caucgugacc uccacauaug gauggacugc gaauauggag cgcauuauga     1920

aagcccaggc acuuagagau aacucuacca uggguuacau ggcugccaag aagcacuugg     1980

aaaucaaucc agaccauagc auaaucgaga cacugaggca gaaagcugaa gccgauaaga     2040

acgacaaauc agucaaggac cucgugauuc ugcuuuauga gaccgcacug uugaguuccg     2100

gcuuuagccu cgaggauccc caaacucacg ccaaucggau cuaccgcaug auuaaacugg     2160

gguuaggaau cgacgaagau gacccuacgg cugaugacac aucugcggca guuaccgagg     2220

aaaugccacc ccuggagggc gaugacgaua cuucaagaau ggaagaggug gacugaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  6567
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt3)

<400>  6567
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucca agcuggauuc uggcaaaggg cuccacauca      120

accuugugcc caauaagcag aaccaaaccc ugacaauugu cgacacuaga auaggaauga      180

cgaaaaccga uuugaucaau aacuuaggua caguuacuaa gucaggcacc aaagccuuca      240

uggaggcucu gcaggcagac gccgauauua guaugaucgg gcauuuugga gugggcuucu      300

acagcgcgua ucuaguagcu aagaagguga cagucauuuc caaacacaau aacgacgaac      360

aguacaccug ggagucuucg gccggugggu cauuuacugu gaggacagau gaaugaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  6568
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt3)

<400>  6568
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaag ugcaccaugg cgaggaagag gucgaaaccu      120

ucgccuuuca ggcugagauc gcacaacuga ugagccucau uauaaacaca uucuacucca      180

auaaggagau cuuucuuaga gaacugauuu cuaacgccuc agacgcguug gauaaaauca      240

gguaugagag uuuaacugac ccuagcaagc uggauuccgg gaaagaacua aagauugaca      300

ucauaccaaa uccgcaggag cggacgcuca cccugguuga uacaggaauc gguaugacua      360

aagcugaccu uauuaacaau cugggcacca ucgccaaguc ugggacaaag gcauucaugg      420

aggccuugca ggcuggagca gauauuucga ugaucggcca guuuggugug ggguucuacu      480

cagccuaucu cguagcugaa aaaguggucg ugauaaccaa gcacaacgac gaugagcaau      540

acgccuggga aagcagugcg ggaggcuccu uuacuguucg cgcagaccau ggcgagccca      600

uugggcgagg aacaaaagug auccugcacc ugaaggaaga ucagaccgag uaucucgagg      660

aacguagagu caaagaggug guaaagaagc auucucaguu cauugguuac ccuaucacgu      720

uauaucugga aaaagagagg gaaaaggaga ucagcgacga ugaggccgaa gaggaaaaag      780

gcgagaagga agaggaggac aaagacgaug aagagaagcc aaaaauugaa gacguugggu      840

ccgaugagga ggacgauuca ggaaaggaca agaaaaagaa aacuaagaaa auaaaggaaa      900

aguacaucga ucaggaggaa cuuaauaaaa ccaagcccau uuggacacgg aacccugacg      960

auaucacuca agaggaauac ggcgaguuuu auaaaaguuu gaccaaugac ugggaggauc     1020

accuggcugu gaagcacuuc agcgucgaag gucagcuaga guuucgcgcc cuccuguuca     1080

uaccaagaag ggcacccuuu gaccuuuucg aaaacaaaaa gaagaaaaau aacauuaagc     1140

uguacgugcg gcgcguguuc aucauggacu cuugcgauga guugaucccu gaauaucuca     1200

auuuuauucg aggggucguu gacuccgagg aucugccauu aaacaucuca agagagaugc     1260

ugcagcagag caaaauucuc aaggugauaa ggaaaaauau cguaaagaag ugucuugaac     1320

uguucaguga guuggcugaa gacaaagaga acuacaagaa auuuuaugaa gccuucucua     1380

agaaccuaaa acugggcauu caugaggauu ccacaaaucg gcgucgccuc agcgagcugc     1440

uuagauacca caccucgcaa ucuggagacg aaaugacguc ccugucagag uaugugagua     1500

ggaugaagga aacucagaaa agcaucuacu acaucacagg cgaguccaag gagcaggucg     1560

cgaacucugc cuuuguggaa cggguucgaa agcgcggguu cgaggugguc uauaugaccg     1620

aaccgauuga ugaguacugc gugcaacagu ugaaagaauu ugacggaaag agccucguau     1680

caguuacuaa agagggucug gaguuacccg aagaugagga agagaagaaa aagauggaag     1740

agaguaaggc aaaauucgag aaucugugua agcuaaugaa agaaauacuc gacaagaaag     1800

uggagaaggu cacaaucucc aacagacugg ugagcucucc uugcuguauu gucaccucaa     1860

cguauggcug gaccgcuaau auggaaagga ucaugaaggc ccaggcccuu cgggauaaca     1920

guacaauggg guacaugaug gcuaaaaagc auuuggagau uaauccagac caccccaucg     1980

uggaaacucu gcgccagaaa gcagaggccg auaagaacga caaagcuguu aaggaccucg     2040

ugguacugcu uuuugagacc gcgcuguuga gcuccggauu cucucucgaa gauccucaaa     2100

cacacucgaa uagaauauau aggaugauca agcugggcuu agguauugac gaggaugaag     2160

ucgcagccga ggagccaaac gcugccgugc ccgacgaaau cccgccucug gagggggaug     2220

aagacgcaag ccguauggag gaaguugauu gaggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  6569
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt3)

<400>  6569
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agagcccugu gggugcucgg ccuuugcugu guccuguuga      120

ccuucgggag cguuagggcu gacgaugagg uggacguaga uggaacagug gaagaggacu      180

uagguaaguc ccgggaaggc ucucgcacug augacgaggu cgugcagcga gaagaggagg      240

caauccaacu ggaugggcua aacgccucac agauucguga acucagagag aaaagugaaa      300

aguuugcguu ccaggcugag guuaauagga ugaugaaacu gauaaucaac agccuuuaca      360

agaauaaaga gauuuuucug cgggaauuga ucuccaacgc cucugacgca cucgauaaga      420

uucgccugau cucgcugacg gacgagaaug cccucucagg aaacgaagag uuaaccguga      480

agauaaaaug cgauaaggag aaaaaucugc uucacgucac agacacuggc guggguauga      540

ccagagagga guugguaaag aaccugggga caaucgcuaa aagcggaacc agugaguucc      600

uaaauaagau gacugaagca caggaagaug gccaauccac aucugagcuc auuggccagu      660

uugggguugg auucuauagc gccuuucugg uggcugacaa ggucaucgug accuccaaac      720

auaacaauga cacgcagcac auuugggaau cagauaguaa cgaguucagc gugaucgccg      780

accccagggg uaauacucuu ggccggggga ccacaauaac ucuggucuug aaggaggaag      840

cgucugauua ccucgagcug gacaccauua aaaacuuagu uaagaaauau ucccaguuua      900

ucaauuuccc uauuuacgug uggucaagca agacagaaac cguagaggaa ccaauggagg      960

aggaagaggc agccaaagaa gagaaggagg aaagugauga cgaggcugcc guggaagagg     1020

aagaggagga aaagaaaccg aagacgaaaa aggucgagaa aacugugugg gauugggaac     1080

ugaugaacga caucaagccc aucuggcaac gcccuucuaa ggagguugaa gaggaugagu     1140

auaaagcauu uuacaagucc uucagcaaag aaucggacga uccaauggcu uauauucauu     1200

uuacagccga gggagaagug accuucaagu cuauacucuu cguccccacu uccgcgccuc     1260

gaggccuuuu ugacgaguac gguaguaaaa agucagacua caucaagcug uaugugagaa     1320

ggguauucau uacagaugac uuucacgaua ugaugccaaa auacuugaac uucguuaagg     1380

ggguggucga cagcgaugac cuaccccuga augugucccg ggaaacccuc cagcagcaua     1440

aacugcuuaa ggucauccgu aaaaagcugg ugcgcaagac guuggauaug auuaaaaaga     1500

uagccgacga uaaauauaac gacaccuuuu ggaaggaguu cggaacaaau aucaaacucg     1560

gcguuaucga ggaucacucu aacagaacua ggcuggcaaa guuacugcgg uuucagagcu     1620

cacaccaucc uaccgacauu acaagucuag aucaauacgu ggaacgaaug aaagagaagc     1680

aggacaagau cuauuucaug gcuggcucca gccgcaaaga agccgagucu ucaccauuug     1740

uagagagacu ccugaagaaa ggguacgaag ucauuuaucu uacugagccg guggacgaau     1800

acuguauaca ggcuuugccc gaguucgaug gaaagagguu ucaaaauguu gccaaagaag     1860

gugugaaguu cgacgagagu gagaagacca aagaaagccg ggaggcaguc gaaaaggagu     1920

uugaaccucu gcucaacugg augaaagaua aggcccugaa agacaagauc gagaaggcug     1980

ugguauccca gcgccuuaca gagucuccau gcgcgcuggu ggcaucgcag uacggcugga     2040

gcgggaauau ggaaagaauu augaaagccc aggcuuauca aaccggaaag gauaucucca     2100

cuaacuacua ugccucacag aaaaagacgu ucgagaucaa ucccaggcac ccuuugauuc     2160

gugacaugcu ccggcgaaua aaagaagaug aggacgauaa gacaguucug gacuuagcag     2220

ucgugcuguu cgaaaccgcc acucuaagaa guggcuaccu ccugccagau accaaggcuu     2280

auggugacag gaucgagcgc augcuucggu ugucucugaa cauugauccc gacgccaaag     2340

uggaggaaga accggaagag gagccugaag agacagcaga agacaccacu gaggauacag     2400

aacaggacga ggaugaggaa auggacgucg ggacggauga ggaagaggaa accgcgaagg     2460

agagcacugc ugagaaagac gaacucugag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  6570
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt3)

<400>  6570
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagagagc ugagggcucu ccuucugugg ggccggcgcu      120

ugcgacccuu acugcgugcu ccugcccuag cggcugugcc agggggaaag ccgauccucu      180

gccccagaag gaccacagcc cagcuggguc cucggcgcaa cccagcaugg agccuucaag      240

ccggcagacu guucuccacu cagacggcug aagacaaaga ggaacccuug cacucuauua      300

uaucaaguac cgagagcguc caggggucca caucuaagca ugaauuucag gcagagacua      360

aaaagcuccu ggauaucguu gccaggucgc uguacucaga gaaagaagug uucauucggg      420

agcucaucag caaugcuagu gacgccuuag aaaagcugcg ccacaagcua guauccgaug      480

gacaagcguu gccugagaug gagauucauc ugcagaccaa cgcagaaaaa ggcacaauca      540

ccauacagga cacugguauc gggaugacac aggaggaacu ugugucuaau cucggaacca      600

uugcccgaag cggcuccaag gcuuuucugg augcccuuca aaaccaggca gaggcuucaa      660

guaaaaucau uggccaguuc ggggucggau uuuauagcgc cuucauggug gcggacagag      720

uugaagugua cucuaggucc gccgcaccag guucacuggg cuaucagugg uugagcgaug      780

ggaguggagu cuuugagauc gcugaggccu cuggcgugcg gacggguacu aagauaauua      840

uccaccucaa auccgacugu aaggaauuua gcucggaggc ucguguacgc gauguuguga      900

ccaaguacuc uaauuuuguc uccuuccccc uguauuuaaa cgggagaagg augaauacac      960

ugcaagccau uuggaugaug gacccuaaag augugcggga auggcagcau gaggaauuuu     1020

accgauaugu ggcacaggcc cacgacaagc cacgcuacac ucuccacuac aaaaccgaug     1080

cuccgcuuaa caucagauca aucuucuaug uccccgacau gaagccuagu auguuugacg     1140

uuagcaggga gcugggaucc ucuguggcgu uguacagccg gaaaguacua auucaaacaa     1200

aggcaaccga uauacugcca aaauggcucc gcuucaucag aggcgugguc gacucagagg     1260

auauuccccu gaaucuuagu agggaacugu ugcaggaguc cgcccucauc cguaagcugc     1320

gggacguguu acagcagcga cugauaaagu ucuuuauuga ucaaagcaaa aaggacgcug     1380

aaaaauaugc caaguucuuu gaggauuacg gccuauucau gagagaaggg aucguuacgg     1440

caacugagca ggaggugaaa gaagacaucg ccaagcuccu gagguaugag ucuucagcac     1500

uuccuagugg acaguugaca agccuguccg aauacgccuc ucgcaugcgg gcagguacca     1560

gaaacauuua uuaccucugc gcgccaaaua ggcaucuggc ugagcacucg cccuacuaug     1620

aggccaugaa gaaaaaggau acugaagucc uuuucuguuu cgagcaguuu gacgaacuga     1680

cauugcucca ucugcgcgag uucgauaaaa agaaauuaau cagcguggaa accgacauug     1740

uaguugacca cuacaaggag gagaaguuug aagaucgauc cccggcagcc gagugccugu     1800

cagaaaaaga gacggaagaa cuaauggcuu ggaugcggaa cgugcucggc agucguguca     1860

ccaaugugaa ggucacacug agacuugaca cucacccugc cauggugacc guuuuggaga     1920

ugggggcagc uaggcauuuc cugcgcaugc aacagcucgc caaaacacag gaggagcggg     1980

cgcagcuguu acaacccacu cuggaaauaa acccaagaca cgcccuuauc aagaaauuga     2040

aucagcucag ggcuucugag ccuggacugg cacagcuacu gguggaucag auuuaugaaa     2100

acgccaugau cgcugccggc cucguagacg auccccgagc aauggucggu cgccugaacg     2160

agcuuuuggu gaaggcgcug gagcggcauu gaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  6571
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt3)

<400>  6571
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagauca gcucccugcc cacccaacuc uucaaaugcu      120

guuuuugcga cuuccuuaag gugaaaaugc acacaauguc uucaagucau cuguuuuacu      180

uggccuuaug ucugcuaacu uucacgagcu ccgcuaccgc agggccugag acacucugcg      240

gagccgaacu ggucgaugcg cuucaguuug uuugugguga cagaggcuuc uauuuuaaca      300

agccaacugg guacggaucu ucgucaaggc gggcuccgca gaccggcauu guggaugagu      360

gcuguuuccg cagcugcgac cugcgacguu uggaaaugua uugugcaccc cucaaaccug      420

ccaagagugc cagauccgua agggcucagc ggcacacaga uaugccaaag acccagaaag      480

aggugcaucu gaagaaugca ucucgcggua gcgccgggaa caaaaauuac agaaugugag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  6572
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt3)

<400>  6572
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca ugggaaagag caugcuggug cuccuuaccu      120

uccuggccuu ugcuuccugc uguauugcag ccuacagacc uucugagaca uugugcgggg      180

gugaauuagu cgacacucug caguucguuu guggcgauag gggguuuuau uucucacggc      240

cagcgagucg cgugagccga cguuccagag gaauaguaga ggaaugcugu uuuaggucuu      300

gcgaccuagc ucuccuggag acguacugug ccaccccggc aaaaucggaa cgggaugugu      360

caacaccccc uacuguccuu ccagacaacu ucccccgcua uccugugggc aaguuuuucc      420

aauacgauac cuggaaacag agcacacaga gacugaggcg ggguuugcca gcccuccugc      480

gcgcucgaag agggcacguu cuggcaaagg agcucgaggc cuuuagggaa gcuaaacggc      540

aucgucccuu aaucgcccug ccuacccagg acccagcgca cggaggcgca ccgcccgaga      600

uggccaguaa ucgcaaguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  6573
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt3)

<400>  6573
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagcuucu ccaccucugc cuuuggcccc guggcuuucu      120

cacuggggcu ccuucugguc uugccugcag ccuuuccagc gccgguuccc ccuggagagg      180

acaguaagga uguggcugcc ccacacagac agcccuuaac aagcuccgaa aggaucgaca      240

aacaaauucg guacauacug gaugguaucu cugcacuacg caaggagacu ugcaauaaau      300

cgaacaugug ugaaucaagc aaggaggccc ucgcugaaaa uaaccugaau cuuccuaaaa      360

uggcagagaa ggacggcugc uuccagagug gguuuaacga ggaaacgugu cugguaaaga      420

uuaucaccgg auugcucgag uucgaagugu aucuggagua ccugcagaau cgauuugagu      480

ccucugaaga acaggcccgu gcuguccaaa ugagcacaaa agugcucauu caguucuuac      540

agaagaaagc caagaaccug gaugcgauca cuaccccaga ccccacaacc aaugcauccc      600

uuuugacuaa acugcaggcc caaaaccagu ggcuacagga uaugacaacc caucucauac      660

ugagaucauu uaaggaguuc cuucagagua gccugagggc uuugcggcaa augugaggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  6574
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt3)

<400>  6574
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcucu ggcuuagagg cuuccuguug gccagcugcu      120

ggaucauugu gagguccucu ccuaccccag ggucagaggg acacagugcu gcaccggacu      180

gucccagcug cgccuuagcg gcucugccua aggauguccc aaacucccag cccgaaaugg      240

uugaggccgu gaaaaagcau auacuaaaua ugcuccaccu gaaaaagcgg ccugacguaa      300

cacaaccagu gcccaaagca gcccuucuga acgcuauccg caaguugcau gucgguaagg      360

ugggcgaaaa uggguacguu gagauugaag augacaucgg acgacgugca gagaugaacg      420

agcucaugga acagacuucu gagauuauca cguuugccga aucgggcacc gcuagaaaaa      480

cacugcacuu cgagauauca aaggagggua gcgaucugag uguggucgaa agggccgagg      540

uguggcucuu uuuaaaagua ccuaaggcga aucggacucg caccaaaguu acaaucagac      600

uguuccagca gcaaaagcau ccacaggggu cccuugacac cggagaagag gcagaagagg      660

ugggcuugaa gggcgagagg ucugaacugc uacucagcga gaaagucgug gaugcccgga      720

aguccacuug gcacguguuu ccggucucaa guagcauuca gcgccugcuu gaccagggga      780

aaucuucccu ggauguucga aucgcuugug aacaaugcca ggagucagga gccagcuugg      840

ugcuccuggg uaagaaaaag aaaaaggaag aggagggcga agggaagaaa aagggaggcg      900

gugaaggggg agcaggcgcu gacgaggaga aagaacagag ucacagaccc uucuuaaugc      960

ugcaggccag gcaaucugag gaucauccuc accggcgucg cagaaggggc cucgagugug     1020

acgggaaggu aaacauuugc uguaaaaagc aguuuuucgu guccuuuaag gauaucggau     1080

ggaaugacug gauaauugcg ccaagcgguu aucaugccaa cuacugcgaa ggcgaguguc     1140

ccucgcacau cgcagggaca ucuggauccu cacuuaguuu ccacagcacc gucauuaauc     1200

auuaucggau gcgaggccac uccccuuuug cuaaccugaa aucuugcugu gugccaacga     1260

aguugcgccc caugagcaug cuauacuaug acgaugguca gaauaucauc aaaaaggaca     1320

uucaaaacau gauaguugaa gagugcgggu gcucaugagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  6575
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt3)

<400>  6575
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccugc ccgggagagc ccucggagcu gcaugccuuc      120

uguuguuagc cgcggguugg cugggcccug aggcuugggg gagcccaacc ccgcccccua      180

caccagccgc acccccucca cccccuccac cgggaucccc cggcgguucu caggauacuu      240

guacgucaug cgggggauuc aggcggccug aggaacuagg ccgcguggac ggcgauuuuc      300

ucgaagccgu caagcgacac auccugaguc gucuucaaau gagagggagg ccaaacauua      360

cccaugcugu ucccaaagca gccaugguga cagcucugcg gaaguugcac gccggaaaag      420

uacgcgagga cgguagagug gaaauaccuc aucucgaugg ccacgcgagc ccaggggcag      480

acggacagga gagggucucc gagaucauuu cuuucgccga aacugauggc cuggcuucgu      540

cacgggugcg ccuguacuuu uucaucagca augaggguaa ccagaaucuc uuuguugugc      600

aggccaguuu auggcuguau cuuaaguugc ugcccuacgu ccuagaaaaa gggucccgaa      660

gaaaggugag gguaaagguu uauuuccaag agcagggaca uggcgaccgg uggaacaugg      720

uggagaaacg ugucgaucuc aagcgcucug gcuggcacac cuuuccgcug acagaagcaa      780

uucaggcucu uuucgagaga ggggaaaggc ggcugaauuu ggacgugcag ugugauagcu      840

gccaagagcu cgccgugguc ccuguuuuug uggaccccgg agaagagucc caccgaccau      900

ucguaguggu ccaggcgcgc cugggugauu caagacauag gauccggaaa cgcggcuuag      960

agugugacgg gagaaccaac cugugcugua ggcagcaguu uuucauagac uuucgucuca     1020

ucggauggaa ugauuggauu aucgccccua cuggcuacua ugguaacuac ugcgaaggga     1080

guugucccgc auaucuugcu ggcgugccag gaagcgccuc uuccuuccac acagcuguug     1140

ugaaucaaua ccggaugcga ggccugaacc ccgggaccgu caauucaugc uguauuccua     1200

cgaaguugag cacuaugagu augcuauacu ucgacgauga guauaacauc gugaaaagag     1260

acguaccaaa uaugauaguu gaagagugcg gaugcgccug aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  6576
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt3)

<400>  6576
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagag ugcuccuucu gaccgcuuug acauuaugcc      120

acggcuucaa ccuggacacu gagaaugcaa ugacguuuca ggaaaacgcc aggggguucg      180

gacaaagcgu cguucagcua caggguuccc gggugguagu gggcgcgccc caggagaucg      240

ucgcugccaa ucaacgcggg ucucucuacc agugugauua uucaaccgga aguugcgaac      300

cuauucgacu gcaagugcca guugaggcag ugaacaugag ccuuggccug uccuuggccg      360

cuacaacuuc uccgccccag cuccuggcau gugguccuac cguccaucaa acaugcucgg      420

aaaauaccua cgugaagggg cuguguuuuc ucuucggauc aaacuuacgu cagcagccac      480

agaaauuucc cgaggcccug agaggcugcc cucaagagga cagcgauaua gcuuuccuua      540

ucgacggcag uggguccauu aucccacacg auuuuaggcg gaugaaggag uucguaucua      600

cuguuaugga acaguugaaa aagagcaaaa cacuguuuuc ccuaaugcag uauucagaag      660

aguuccgcau ucauuuuacc uucaaggagu uucaaaauaa ccccaauccu agaagucucg      720

ugaagccaau cacgcagcug cuuggaagga cucacaccgc cacagguaua cggaaagucg      780

ugcgcgaacu guucaacauc acuaauggcg cgcgaaagaa cgcauucaaa auuuuggugg      840

ucaucaccga cggggagaag uuuggagauc cgcucggcua cgaagacguu auucccgagg      900

ccgauagaga aggugugauc agguauguaa uagggguggg agacgcuuuc cggagcgaga      960

aaucucguca ggagcugaau acaauugccu ccaagccucc acgcgaucau gucuuucagg     1020

ugaacaauuu cgaagcauua aagaccaucc aaaaccagcu gagagagaaa auuuuugcua     1080

ucgaaggcac gcagacuggc ucaagcaguu cuuucgagca cgaaaugucc caggaggggu     1140

uuagcgccgc gaucacaucg aacggacccc uccuuucuac cguugguucc uacgacuggg     1200

ccggcggggu guuccuguau acuucaaagg agaaaaguac auuuauuaau augaccaggg     1260

ucgauagcga caugaacgac gcauacuugg gauacgcugc cgcuauaauc cuacggaauc     1320

gagugcaauc ccugguacuc ggcgccccuc gcuaucagca cauuggucug guugcaaugu     1380

ucagacagaa cacggggaug ugggaaucua augccaacgu gaagggcacc cagaucggag     1440

cuuacuuugg cgcgagccuu uguucagucg auguggacag uaaugggucc acagaucugg     1500

ucuugauagg agcaccacau uauuacgagc aaacuagggg uggccaggug agcguuugcc     1560

cccucccgcg ggggcgcgcc agauggcagu gugacgcugu gcuguaugga gaacagggcc     1620

aaccuugggg uagguucggg gccgcauuaa ccguacuggg cgaugucaac ggagacaaac     1680

uaacagaugu ggccauuggc gcucccgggg aggaagacaa ucguggagcc guuuaccucu     1740

uucacgguac uucuggcuca gggaucaguc caagccauuc ccagcggauc gcaggaucua     1800

agcugucgcc ucgacuucag uauuucggcc agagcuuguc cggugggcag gaucugacca     1860

uggacggccu cguggaucug acagucggag cgcagggcca cgugcuucug uugagaucac     1920

agcccguacu cagggugaaa gcuauuaugg aguucaaccc acgcgagguu gcccggaaug     1980

ucuuugaaug caacgaccaa guggugaagg ggaaggaggc aggagaaguc agaguuuguc     2040

ugcacgugca gaaaaguacc agggaccgcu uacgagaggg ccagauccag ucugugguaa     2100

cuuacgaucu ggcccuagac agcggucggc cccauucccg ugcugucuuc aaugagacga     2160

agaacucaac aagaaggcaa acccaggugc ucgggcugac ucagaccugc gaaacacuua     2220

aauugcagcu gccuaauugc auugaggauc caguuagccc gauagugcuc cgccugaacu     2280

uuucuuuagu cggaaccccu cuguccgccu ucggcaaccu ucggccugug uuggcagaag     2340

acgcucaaag acucuuuacu gcccuguucc cauuugagaa gaauuguggu aacgauaaua     2400

ucugccagga cgaucuaagu auuacauuca gcuuuauguc ucuggacugu cucguugugg     2460

gcgggcccag ggaguucaac guaacgguca ccgugcgaaa ugauggagaa gacuccuacc     2520

gcacucaggu gacauuuuuc uuuccucugg aucuuucaua ucggaaaguc aguaccuugc     2580

aaaaccagag aagccagagg ucguggcguc uggcgugcga guccgccucu agcacagaag     2640

uuucaggcgc uuuaaagagu acuuccuguu cuaucaauca cccaaucuuc cccgagaaca     2700

gcgaagugac cuucaauauu acguuugacg uagauuccaa ggcaucacuc gggaacaaac     2760

ugcuucugaa ggccaaugug accagcgaga acaauaugcc gcgcacaaac aaaacugagu     2820

uccaguugga acucccuguc aaguacgcug uguauauggu ugugaccagu cauggagucu     2880

cuacaaaaua ccugaauuuu acugccuccg agaacaccag ccgggugaug caacaccagu     2940

aucagguuuc gaaccuaggc cagagaucac ugccaauauc ucucguguuc cugguccccg     3000

uaaggcuuaa ucaaacggug aucugggacc gaccucaggu uacauuuagu gaaaacuugu     3060

ccucuaccug ccauacuaag gagcggcugc ccagccacag cgacuucuua gcagaacucc     3120

gcaaggcgcc aguggucaau uguuccauug ccgugugcca gagaauccag ugugauauuc     3180

ccuuuuucgg uauccaagag gaauuuaacg cuacacugaa agggaaucuu ucauucgacu     3240

gguacauaaa gaccagucac aaccaucugc uaaucguaag cacugccgag auucucuuua     3300

augauucugu guucacccug uugcccggac agggcgcauu cgucaggucc cagacagaga     3360

cgaaaguuga accauuugag gugccgaacc cucugcccuu aaucgugggu ucaagugucg     3420

gcgggcuccu gcuucuggcu uugauuaccg ccgcacucua uaagcuggga uucuuuaaac     3480

ggcaguacaa ggacaugaug agcgaaggcg ggccacccgg agccgagccu caaugaggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  6577
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt3)

<400>  6577
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucagccuga agacccuccc cuuucuucug uuguuacacg      120

ugcagaucuc caaagccuuc ccugucucuu caaaggagaa aaacacaaag acuguucaag      180

acuaccugga aaaauuuuau cagcuaccaa guaaucagua ccagagcacg agaaagaacg      240

gcaccaaugu gauuguagag aagcucaaag aaaugcaaag guucuuuggg cugaacguga      300

caggaaagcc gaaugaggaa acucuugaua ugaugaaaaa gccccggugc ggugucccug      360

acuccggcgg guucaugcug accccaggaa accccaaaug ggagcgcaca aauuugaccu      420

aucgaauacg uaacuacacu ccucagcucu cugaggcuga aguggagaga gcaaucaagg      480

augccuuuga acuguggucg guugcgucac cacugauuuu cacaaggauc agccagggcg      540

aggcugacau uaauaucgcc uuuuaucagc gggaucaugg ugacaacagu cccuucgaug      600

ggccuaaugg aauacucgca cacgccuuuc aaccaggcca gggcaucggg ggagacgcuc      660

auuucgaugc agaggaaacc uggacgaaca cuuccgccaa uuacaacuua uuucuggugg      720

cugcccacga guucggucau ucucuuggcu uggcgcacag cuccgacccg ggggcacuga      780

uguaucccaa uuacgccuuc cgcgaaaccu caaacuacag ucuaccucag gaugacauug      840

auggaaucca ggcuauuuau ggccucagcu cuaacccaau ccaacccaca gguccuucca      900

cuccaaagcc cugugacccg ucacugaccu uugacgccau aacaacccuu agaggggaga      960

uucuguucuu uaaagauagg uacuucuggc ggcgccaccc ucaguugcag cgagucgaaa     1020

ugaauuuuau cagccucuuc uggcccaguc ugccaacggg cauucaagca gcuuaugagg     1080

acuuugauag agacuuaauc uuccuguuua agggaaacca guacugggcc cucucuggcu     1140

augauauccu ucagggguac ccuaaagaca uuuccaauua uggauucccc agcucggugc     1200

aggcgauaga ugccgcagua uuuuacaggu cuaagacuua cuucuuuguu aacgaccaau     1260

ucuggcggua ugauaaucag cgucaguuca uggagccagg uuaccccaaa uccaucucag     1320

gcgcuuuucc ugggauugaa aguaaggugg acgccgucuu ccagcaagag cacuuuuucc     1380

auguguuuag cggaccacgc uauuacgcuu ucgaucugau cgcccagaga gugacaaggg     1440

ucgcacgggg caacaaaugg uugaauugcc gauaugguug aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  6578
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt3)

<400>  6578
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguggc agccccucgu gcuuguccug uugguuuuag      120

gcugcuguuu cgccgcuccu agacaaaggc aguccacccu ggugcuauuu ccaggggacc      180

uccggacaaa ccugacugau cgccagcuug cagaggaaua ccuguaucga uacggauaua      240

cgcguguagc cgagaugaga ggugaaucua aaucauuggg cccggcgcuc cugcugcucc      300

agaaacaauu aagucugccc gagaccgggg aacuugacag cgcuacauug aaggccauga      360

ggacuccucg gugcggagug ccagaucugg gccgcuucca gaccuuugag ggugaccuaa      420

aauggcacca ucacaauauc acauacugga uucagaacua uuccgaggau cuccccagag      480

cagucauaga cgaugccuuc gcuagggcau uugcccugug gucugcugug accccucuua      540

cuuucacacg gguuuacucg cgcgacgccg auaucgugau ucaguuuggg gucgcggaac      600

auggagacgg cuauccauuc gauggcaagg acgggcuguu ggcacacgcc uuucccccug      660

gaccagguau ccaaggcgau gcucauuucg acgacgauga gcucugguca cuggggaaag      720

gagugguagu uccgacccga uuuggcaaug ccgacggugc agcuugucac uuccccuuua      780

uuuucgaagg gagaagcuac agugccugca cgacugaugg aagguccgac ggcuuaccuu      840

gguguucuac cacagcgaac uacgauacug acgaucgguu cggcuuuugc ccaagcgagc      900

gucuguauac ccaggacggg aaugccgaug gaaagcccug ucaguucccu uuuaucuucc      960

agggucaauc cuacucagca ugcacaaccg acggccgcag ugauggguau agauggugug     1020

cuacgacugc caacuacgac agggacaagc ucuuuggauu cugcccaaca cgggcugaua     1080

gcaccgugau gggcgguaau ucugccgggg agcuuugugu cuuucccuuc acuuuucugg     1140

gcaaagaaua uuccacaugc accucagagg gacgaggcga cgggcgcuug uggugcgcaa     1200

cgaccagcaa cuucgauagu gacaagaaau ggggauuuug uccggaucag gguuacucuc     1260

uauuccuggu ggccgcucac gaauuuggcc augcgcucgg gcuggaccac uccagcgugc     1320

cugaggcacu uauguauccc auguacagau ucacagaagg accaccucug cauaaggaug     1380

acgucaaugg cauaaggcac uuguacgguc cccggccaga gcccgagccu cgcccaccga     1440

cuaccacaac uccccagccu accgccccac ccacaguuug cccuaccggg ccacccacug     1500

ugcacccguc ggaaagaccu acggcuggcc caacaggacc cccuucugcc ggccccaccg     1560

ggccaccuac ugcaggaccc uccaccgcca caaccguacc acucucaccg guggaugacg     1620

cuuguaacgu caauaucuuc gaugccauug cagagaucgg uaaccaacug uauuuauuua     1680

aagacggcaa guacuggagg uucagugaag ggcguggaag ccggccucag ggccccuuuc     1740

ugauugcgga uaaguggcca gcucuacccc gaaaacucga cuccguguuc gaggaaagac     1800

ugucuaagaa auuguuuuuc uuuagcggua ggcagguuug gguguauacu ggggccucag     1860

uccuuggccc ucgccggcug gacaagcucg gacugggcgc agauguggcc cagguaacag     1920

gggcucuuag aaguggaagg ggcaaaaugc uguuguucuc cggucgccga cucuggcggu     1980

uugacguuaa ggcccaaaug guggauccac guagcgcauc ugaggucgac agaauguucc     2040

ccggggugcc ucuggauacg caugacgucu uucaguacag ggagaaggcu uauuucugcc     2100

aggaucgcuu uuacuggcgg gugucaagua gaagcgaauu aaaucagguu gaccaagugg     2160

gauauguaac cuacgauauc cugcaguguc cggaggacug aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  6579
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt3)

<400>  6579
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg ugcuggccgc uuuccucuuu cuuagcugga      120

cccauugcag agcacugccu uugccauccg ggggagacga ggaugacuua ucugaagagg      180

aucugcaguu cgccgaaagg uaccuacggu cauauuacca cccgacaaac cucgcgggua      240

uccugaagga gaaugcugcc aguagcauga cugaacgccu ucgagagaug caauccuuuu      300

ucggccugga ggucacgggg aaauuggacg auaacacccu cgacguuaug aagaaacccc      360

guuguggagu gccugaugua ggcgaauaua auguguuucc aagaacacug aaguggucua      420

aaaugaaccu gacuuacagg auugucaauu auacccccga caugacacau ucggaggugg      480

aaaaggcauu caagaaagcc uuuaagguuu ggucagaugu gaccccucuc aacuucacuc      540

gguuacacga cgguauagcu gauaucauga uuagcuuugg gaucaaagag cauggagacu      600

ucuacccauu ugauggcccc aguggccugc uugcacacgc cuucccucca gggccgaauu      660

auggagguga cgcucacuuu gacgaugacg agacauggac cuccucuagc aagggcuaca      720

acuuguuccu ggucgccgcg caugaguucg ggcacucccu aggacucgau cauucaaaag      780

accccggcgc acugauguuu ccuauuuaca cguauacugg uaagagucac uucaugcuuc      840

cagaugacga ugugcagggg auccagagcc uguacggacc cggcgacgaa gauccuaauc      900

caaagcaccc caaaaccccg gacaagugcg auccuucuuu gucccucgac gccauaacau      960

cacugcgcgg cgaaacuaug aucuuuaaag acagauucuu uuggagguua cauccccagc     1020

aaguagaugc ugagcuguuc cucaccaaga gcuuuuggcc agaacuuccu aaccggauug     1080

acgccgcaua ugagcacccc agucaugauc ugaucuucau uuuucgcggg cgaaaauucu     1140

gggcuuugaa uggauacgac auccuagagg guuauccaaa gaaaauaucu gaacugggcc     1200

uccccaagga gguuaagaaa auuuccgccg cggugcacuu ugaagauaca gggaagaccc     1260

ugcuuuucag cggaaaccag gucuggagau acgacgauac gaaucauauc auggacaaag     1320

auuauccuag gcugauugag gaagacuuuc caggcaucgg ugauaaggug gacgccgugu     1380

acgagaaaaa cggguacauc uauuucuuca auggcccgau ucaguuugag uacucgauau     1440

ggucuaaccg gaucguccgu guuaugcccg caaacuccau uuuguggugu ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6580
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt3)

<400>  6580
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acacaacuga agacuacgau acgaccacag      120

aguucgacua uggcgaugcc acuccuugcc agaaggugaa ugaaagagcu uuuggggcac      180

aacugcuccc accgcuuuac agccuggucu ucguuaucgg auuggugggu aacauuuuag      240

uagugcuggu ccuagugcag uauaaaaggc ucaagaauau gaccuccaua uaccugcuua      300

accuggccau cucugacuug cucuuucugu ucacacugcc cuuuuggauu gauuauaaac      360

ucaaggacga uuggguuuuc ggcgacgcga uguguaaaau cuuaucaggg uuuuacuaua      420

ccggacugua cagugagauu uucuuuauca uacuuuugac uaucgaucgg uaccuggcua      480

uugugcacgc cgucuucgca cuacgcgccc gaacagugac cuuuggcgua aucacgagca      540

uuaucauaug ggcucucgca auucuggccu ccaugccugg ucuuuauuuc ucuaagacuc      600

agugggaauu uacccaucac acaugcucgc ugcauuuccc acacgaguca uugcgugagu      660

ggaaacucuu ccaggcucug aaguuaaauc uguuugggcu cguucuuccc cuguugguga      720

ugaucauuug uuacacugga aucaucaaga uucuacugag aaggccuaac gagaaaaaga      780

gcaaagccgu ccggcucaua uucgugauca ugauuaucuu uuuccuguuu uggaccccau      840

auaaucuuac aauacugauu aguguguucc aagacuuuuu guucacccau gaaugcgaac      900

agucccgcca ccucgaucug gcgguccagg uuacggaggu gaucgcauac acucacuguu      960

gcguaaaccc cgugaucuau gccuuugucg gcgagagauu caggaaguac uuacggcagc     1020

uguuucaucg ccgaguggcu guucaccuag ugaaguggcu cccuuuccug ucugucgaca     1080

gacuugaaag ggugagcucc acaucaccaa guaccggcga gcaugaauug agcgccgggu     1140

uuugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  6581
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt3)

<400>  6581
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agaacccugg ccugccuccu ucuguuggga uguggguacu      120

uagcucacgu gcuggcagag gaagccgaga uccccaggga agucauugag cggcuagcgc      180

gcagccagau acauuccauc cgagaccucc aacgucugcu ugaaauugau ucuguuggau      240

cagaggacag ucuggauacu agcuugagag cucacggugu gcaugccaca aagcacguac      300

cugagaaaag gccacucccg auccggcgca agagauccau ugaagaggca gugcccgccg      360

ucugcaaaac gaggaccgug aucuaugaaa uaccucgguc ucagguugac ccaacaucgg      420

cuaacuuccu gaucuggccc ccuugugugg aggucaagcg cugcacuggc uguugcaaua      480

ccucaagcgu gaaaugucag ccaagucgag uacaucacag auccguuaag guggcaaagg      540

ucgaguacgu gaggaaaaag cccaaacuga aggaagugca gguccggcuc gaggaacacu      600

uagagugcgc cugugcuaca accucucuga acccugauua ucgugaagag gacacugggc      660

gcccaagaga gagcggcaaa aagaggaagc ggaaacgacu uaagccgaca ugaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  6582
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt3)

<400>  6582
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagaugcu gggcccuguu ccucagccuu uguugcuacc      120

ugagguuggu guccgcugag ggcgacccca ucccugaaga guuauaugaa augcugucug      180

aucacucaau ucggaguuuu gacgaucuac agcgccuccu gcauggggac ccaggagagg      240

aagauggugc agagcuugac cugaauauga cccgaagcca cuccggcggg gaguuggaau      300

cucucgcccg uggaagaagg ucgcugggcu cacugacaau agcggagccg gcuaugaucg      360

ccgaauguaa gacucggacg gaggucuucg agauuagccg cagacucauc gauaggacca      420

acgcaaacuu uuuaguuugg cccccuugcg uggaaguaca acgguguagu gguugcugua      480

auaaucgcaa cgugcagugc cgaccaacac agguccagcu gagacccgug caaguuagga      540

aaauugagau cgugcggaag aaaccuauau ucaagaaagc cacugucacc cuugaagacc      600

auuuggcuug uaagugcgag acaguggcag ccgcucgucc aguaacccgc ucccccgggg      660

gaucucagga acagagagcc aagacuccuc agacaagggu uaccauccgg acggugcgag      720

uccgcagacc accgaaaggc aagcacagga aauuuaagca uacucacgau aaaaccgcgc      780

ugaaggagac acuaggcgca ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  6583
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt3)

<400>  6583
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguucg gccuccuucu guugaccucc gccuuagcug      120

ggcagagaca aggaacacag gcagagucua accugucaag uaaguuucag uucagcucca      180

auaaagaaca gaacggugug caagaccccc agcacgagag gaucauuacu gucucuacga      240

auggcucgau acauucaccu cgguuuccac acaccuaccc gcgcaacaca guucuagugu      300

ggcgacucgu agccguggaa gagaaugucu ggauccagcu gacuuucgau gaacguuuug      360

ggcuugagga ccccgaggau gacauuugca aguaugauuu cguggaaguu gaggaaccua      420

gcgacggaac cauccugggc agauggugug guagugggac agugccagga aaacagauuu      480

ccaagggcaa ccaaaucagg auacgguuug ucucugauga guacuucccc agcgagccug      540

gcuuuugcau ccauuauaau auugugaugc cacaguucac cgaagcggua ucccccucag      600

uuuugccucc aagugcucuc ccgcuggacc ugcucaacaa ugccaucacu gcauuuagca      660

cauuagagga ucugauucgc uaccuugaac ccgagagaug gcaguuggac cuggaagauc      720

uauauaggcc uaccuggcag cuccugggga aagccuucgu guuuggacgg aagucucgcg      780

ucguggaccu uaaccuguug acggaggagg ugcgacucua cuccuguacu ccaagaaauu      840

ucucagucag caucagggag gaacugaagc ggaccgauac aauauucugg cccgguugcu      900

uacugguuaa acguuguggc gggaacugcg cuuguugccu ccacaauugu aacgaaugcc      960

aaugugugcc uaguaaggua acuaaaaagu aucaugaggu gcuucagcug cgcccaaaaa     1020

ccggagucag aggcuugcac aagucucuaa cagacguggc acuggaacac caugaggagu     1080

gcgacugcgu uuguaggggu uccaccgggg gaugaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  6584
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt3)

<400>  6584
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagacuga ucuucgugua cacccucauu ugcgccaacu      120

uuuguagcug cagggacaca uccgcuacuc cccagucugc aucaauaaag gcccuucgga      180

augcgaaccu gcgccgagau gacuuguauc guagagauga gacgauccaa gucaaaggaa      240

auggguacgu ucagaguccu agguucccaa acagcuaucc gcggaauuua cugcuaaccu      300

ggcgccucca uucccaggaa aacacaagga uucagcuggu guuugacaau caauucggac      360

uugaggaagc ugagaacgau aucuguagau acgacuuugu agaaguggag gauauuucug      420

agacuucgac caucauacgg ggucgcuggu gcggccacaa ggaagugccc ccucgaauca      480

aaucaagaac aaaucagauu aagaucaccu ucaaaagcga cgauuauuuu gucgccaagc      540

caggguucaa gauuuacuau agucuguugg aggacuuuca gcccgcagcc gcuuccgaaa      600

cuaacuggga gucuguuaca agcuccaucu caggagugag uuacaauagc ccuucuguca      660

ccgauccaac gcucauagca gacgcccugg auaaaaagau ugcugaguuc gacacugugg      720

aagaccugcu caaauacuuu aaccccgagu ccuggcagga agauuuagag aauauguauc      780

uggacacccc uagguaccgg ggccguucau aucaugaucg caagagcaaa guagaccuug      840

auagauugaa cgacgaugcc aagagguaca guuguacacc acggaauuau ucuguuaaca      900

uccgagagga acugaagcua gcgaacgugg ucuucuuucc gcgcugccuc cuggugcaaa      960

gauguggugg gaauugcgga uguggcacug ugaacuggag guccugcacc uguaauagcg     1020

gcaaaacagu caagaaauac cacgagguuc uucaguucga acccgggcau auuaagcggc     1080

gcggcagagc aaaaaccaug gcccuggugg acauccaguu ggaucaccac gagaggugcg     1140

acugcaucug uucgucucgu ccuccacggu gaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  6585
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt3)

<400>  6585
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugacccaca gcaaguuccc cgccgcuggc auguccagac      120

cucuggacac aucucucagg cuuaaaacuu uuucaaguaa gagcgaguac cagcuggucg      180

uuaacgcagu gcggaaauug caagaauccg gguucuauug gucugccgua acgggaggug      240

aggcgaauuu acugcuaucg gcugaaccag ccggcaccuu ucucauccgc gauucaagcg      300

accagcgaca uuucuuuaca cugaguguga agacucaguc cgggaccaaa aaccuucgua      360

uucagugcga gggaggcucu uucagccugc aauccgaucc gagaucaaca cagcccgucc      420

cuagguuuga cuguguguug aagcucguuc accauuacau gccacccccu ggugcaccaa      480

guuuccccag cccuccaacc gaaccgucuu ccgaggugcc cgagcagccu ucagcccagc      540

cacugcccgg gagcccucca cggcgcgcuu auuacauaua uaguggaggc gaaaagaucc      600

cccugguccu cucuagaccg uuauccagca auguggcaac ucugcaacac cuuugcagga      660

aaacaguaaa cggccauuug gauucguacg agaagguuac ccagcugccu gggcccauuc      720

gggaauuucu agaccaguau gaugccccac ucugaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  6586
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt3)

<400>  6586
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugcccagcg ccggccagcu ggcucucuuc gcacuuggga      120

ucguccuggc cgcgugccag gcuuuggaga acuccaccuc uccuuuauca gccgacccac      180

cgguugcagc cgcuguggua agucacuuua augauugucc cgacagccau acacaauucu      240

gcuuucacgg aacuuguaga uuccuggugc aggaagauaa gccugcaugc gucugucauu      300

ccgguuacgu gggcgccagg ugcgagcacg cugaccuacu cgccguugug gcggcaucuc      360

agaaaaagca agccauuacg gcucuggucg ugguaucgau aguugcccuu gcagugcuga      420

ucauuaccug ugucuugauc cauugcuguc aggugcggaa acacugcgaa uggugucgcg      480

cucucauuug ccgacacgag aagccaucag cccugcugaa agggcguaca gcgugcuguc      540

auagcgaaac uguggucuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  6587
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt3)

<400>  6587
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccccuagcg gccugagacu ccuuccacug uuguuaccgc      120

ugcuauggcu ccuggugcuu acccccggga ggccugccgc uggacugucc acaugcaaga      180

cuaucgacau ggaguugguc aaacggaagc gcauugaagc aauacgaggu cagauccucu      240

cuaaacugcg ucuggccuca ccacccaguc aaggcgaggu uccuccaggg ccccucccug      300

aagcgguguu agcucuguac aacagcacga gagauagggu agccggagag uccgcagaac      360

cagagccgga gcccgaagcc gacuauuacg cuaaggaggu gacccggguc cuuauggugg      420

aaacacacaa ugagauuuau gauaaauuca agcagucuac ucauucgauc uacauguuuu      480

ucaacaccuc agaguugcgc gaagcaguuc cugagccagu gcugcuaagc agagccgaac      540

ucaggcugcu ucggcugaag uugaaagucg agcagcacgu ggaacucuau cagaaguaca      600

guaauaacuc cuggcgcuau cugucuaauc gauuacuggc ucccagcgac uccccugagu      660

ggcucucauu ugauguaaca ggcguuguga gacaauggcu uaguaggggu ggggagauug      720

aaggauuccg gcugagcgcc cauuguucuu gcgacucccg ugauaacacc uugcaggucg      780

acaucaaugg cuuuacuaca ggccgcagag gggaucuagc gaccauacac ggaaugaaca      840

ggccauuccu gcuccugaug gcaacgcccc uugagcgggc ccagcaucug cagucaagcc      900

gacaccgcag agcuuuggac acuaauuacu guuuuaguuc uaccgagaaa aacugcugug      960

ugaggcaacu cuacaucgau uuccggaagg accuggguug gaaauggauu cacgaaccga     1020

agggcuauca ugccaauuuu ugcuuagggc cuugucccua caucuggucc cuggauacac     1080

aguauagcaa ggugcuagca cucuacaacc agcacaaucc aggagcuucg gccgcgccuu     1140

gcuguguccc ccaggcccug gaaccacuuc ccauuguuua uuacgugggc cgcaaaccua     1200

agguagagca auugucuaac augaucguga gauccugcaa auguucauga ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  6588
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt3)

<400>  6588
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg ugcugagcgc cuuccucauc cuucaucugg      120

ucaccguugc uuuguccuua ucuacauguu caacucugga cauggaucag uuuaugagaa      180

agaggauuga ggcaauacgg ggccaaaucc uaaguaaacu caagcugacg agcccucccg      240

aagacuaucc agagccggaa gaggugcccc cugaaguaau uuccaucuac aacucuaccc      300

gcgaucuucu gcaggagaaa gccucgcgac gugcggcugc cugcgagaga gaaaggucag      360

acgaggaaua uuacgcaaag gagguguaua aaauugauau gccacccuuc uuuccuagcg      420

agaaugccau cccacccaca uucuaccggc cuuauuuucg cauagucaga uucgacguga      480

gugcuaugga aaagaacgca uccaauuugg uuaaggccga guuuagggug uuccggcucc      540

agaacccaaa agcucgcguc ccggaacagc gaaucgagcu guaccaaauu cugaagucua      600

aagaucucac uagccccacc cagagauaca ucgacuccaa ggugguaaaa acaagggccg      660

aaggggagug guuaucauuu gauguuaccg acgcggugca cgaguggcug caucacaagg      720

aucggaaucu uggauucaag auuaguuugc auuguccuug cuguacuuuu gucccaagca      780

acaauuauau cauacccaac aaaucugagg aacuggaagc acguuucgcc gguauugacg      840

gcacauccac cuacacguca ggggaucaga agacuaucaa aagcacccgc aagaaaaaua      900

guggaaagac accucaccua cuccugaugc uucugccauc uuauagauug gagucccagc      960

aaacuaacag gcggaaaaag cgagcucucg acgccgcaua cugcuuucgc aaugugcagg     1020

acaacuguug ccugagaccc uuauauauug auuucaagag ggaccugggc uggaaaugga     1080

uccacgaacc gaaggguuac aaugcuaacu ucugugccgg ggcgugcccu uaucucugga     1140

gcucggauac ccagcauucu cgggugcuuu cccuguacaa uacaaucaac cccgaggccu     1200

cagcaagucc auguugcguc agccaggacu uggagccucu aaccauucug uacuauauag     1260

gaaaaacgcc caagaucgaa caacucucca acaugauugu uaaaucuugc aaguguagcu     1320

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  6589
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt3)

<400>  6589
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcauc ugcagagagc ccucgugguc cuugcucugu      120

ugaacuucgc aaccguuagc uuaucccugu cuacaugcac uacgcuagac uuuggccaca      180

ucaaaaagaa aaggguggag gccauucggg ggcaaauacu cucaaagcug cgccuuacca      240

gucccccuga accaacagua augacucacg ugccguacca gguccuggcg uuguauaaua      300

gcacccgaga gcuccuggaa gagaugcaug gagaacguga ggaggguugu acacaggaaa      360

acaccgaguc cgaauacuau gcuaaagaga uccacaaguu cgauaugauu cagggccugg      420

ccgagcauaa ugaacucgca gugugcccca aggggaucac uucuaaaguu uuuagauuca      480

acgugucguc agucgagaag aauaggacaa acuuauuucg ggccgaguuc cgcgugcuga      540

gaguaccuaa uccaagcagu aaaaggaacg aacaacggau ugaacuuuuu cagaucuugc      600

gccccgacga gcacauagcu aagcagcgau acaucggagg caaaaaucug ccuaccagag      660

guacggcaga guggcuaucc uucgauguua cugacaccgu gagggaaugg cuccugcggc      720

gugagucuaa ccuugggcug gaaauuagca uccacugucc augccauaca uuucagccca      780

auggagauau uuuggagaac auccacgaag ucauggagau aaaguucaag ggcguggaca      840

augaggauga ccauggccgc ggggaucucg gaagacugaa aaagcaaaaa gaccaccaca      900

acccucauuu aauucugaug augaucccac cgcacaggcu cgauaauccc ggucagggcg      960

ggcagcggaa gaaacgagcc cuugacacua acuauuguuu ucgcaaccug gaagagaauu     1020

gcugugugag accuuuguac auugauuuca ggcaggaccu aggauggaag uggguccaug     1080

aaccaaaagg cuauuacgcu aacuuuugcu ccggucccug uccuuaccug cggucagccg     1140

acaccacaca caguaccguu cucgggcugu auaauacgcu uaacccagag gcgagcgcau     1200

cucccugcug ugugccgcaa gaucuggaac cuuugacuau ccucuacuau guaggacgca     1260

cacccaaggu ggagcagcug uccaauaugg ucgugaaguc augcaaaugc agcugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6590
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt3)

<400>  6590
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccccgugg cugucugggc agcccuggcg guuggccucg      120

agcuuugggc ugccgcacac gcccugccug cucagguggc auucacccca uacgccccgg      180

aacccgggag cacaugcaga uugagggagu auuacgacca aacugcucag auguguugcu      240

ccaaguguuc uccuggacag caugccaaag uauuuugcac gaagaccuca gauacagugu      300

gugacaguug cgaagauagc acuuauaccc aguuauggaa cuggguccca gagugucugu      360

ccugcgguuc ucgguguucg ucagaccaag uggaaacaca ggcgugcacc cgcgagcaga      420

aucgaaucug uacuugccgu cccggcuggu acugcgcacu aagcaaacag gaggggugua      480

gacucugcgc cccucugagg aagugucggc caggauucgg cguugcucgc cccgguacag      540

aaaccaguga uguggucugc aaaccuugug ccccagggac guuuuccaac acuaccucua      600

gcacagacau uugcagaccg caccaaauau guaauguggu agcaaucccc ggaaacgcuu      660

ccauggaugc cguuugcacu ucaaccaguc cuacaaggag cauggcgcca ggcgccgugc      720

aucuucccca gccugucucu acccgguccc agcacacgca gccaacuccc gagccgucaa      780

cagcaccuag caccaguuuc cuguugccca ugggcccauc uccucccgcu gaagggucca      840

cuggagacuu ugcccuccca gugggucuga uugugggcgu cacagcucug gggcucuuaa      900

ucauuggagu ugugaauugu guaaucauga cccaagugaa gaagaaaccc cugugccuuc      960

agcgcgaggc caaggucccu cauuugccag cagauaaagc ccgaggcacg caggguccgg     1020

agcaacagca ucugcuaaua accgcuccca gcucgucuuc cucaagucuc gaaagcuccg     1080

cgucugcacu ggacagaagg gccccuacac ggaaccagcc acaggcuccc gggguggagg     1140

ccagcggagc aggcgaagcc cgugcuucaa cuggcaguuc cgauagcucu ccugggggac     1200

acgguaccca aguuaaugug acauguaucg ucaacgugug cucaaguagc gaccacuccu     1260

cucagugcuc gagccaggcc uccucaacua ugggcgauac cgacaguucu ccaagcgagu     1320

cccccaagga cgaacaggua ccguucucaa aagaggagug ugcauuucgc agccaacuug     1380

aaacaccuga gacccuguug gggucuacug aagagaagcc acucccccug ggaguuccug     1440

augcgggcau gaagcccucc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  6591
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt3)

<400>  6591
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgugauga gacuguuccc uugcuuucuc cagcuucugg      120

ccggcuuggc uuuaccagca gucccgcccc aacagugggc ccugagcgcg gggaacggau      180

ccucugaggu ugaaguggua ccuuuccagg aggugugggg uaggucauac ugucgggcuc      240

uagaacgccu cgucgacgug guuagugagu auccaagcga aguggagcac auguuuuccc      300

ccucuugcgu cucgcugcuu cgauguaccg gcugcugugg ggaugagaau cugcauugcg      360

ugccuguaga aacagccaac guuacuaugc aguugcucaa gauccguuca ggagacagac      420

caagcuacgu ggagcugacg uucagucaac acgucaggug ugaaugccgg ccccugcgcg      480

agaaaaugaa gccugagaga aggcggccaa aaggccgcgg uaagcgaaga agggaaaaac      540

agcggccgac cgauugucau cucugcgggg acgcagugcc ccgucgcuga ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  6592
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt3)

<400>  6592
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgacagac agacagauac ugcccccagc ccuuccuacc      120

aucugcuccc aggcaggcgg cgcacggugg acgcugcagc cucucgaggg caaggaccgg      180

agcccgcgcc ugguggcggg gucgaaggag uuggcgcucg ugguguggcc cuuaagcugu      240

ucguacaguu guuagggugc ucaagauuug gaggcgcagu ggucagggcc ggcgaggcug      300

aaccaagugg ggcagcccgg agcgcuuccu cuggacgcga ggaaccccag ccugaggagg      360

gugaagagga agaggagaaa gaagaggaaa gaggcccaca guggaggcug ggggcccgga      420

agcccggauc guggaccggc gaggcggcag ugugugccga uucagcuccu gccgcacgcg      480

cuccacaagc ccuagcgcga gccagcggua gagggggaag gguugcacgg cguggcgcug      540

aagagagugg cccgccccac uccccuucuc gcagagggag cgccuccagg gcuggaccag      600

gucgggccuc agagacaaug aacuuccucc ugaguugggu gcacuggagc cuugcacugu      660

ugcucuaucu gcaucacgcc aaauggucuc aggcugcgcc cauggcagaa ggcgggggac      720

agaaucauca cgaggucgug aaguuuaugg acguauacca gcgauccuau ugccacccua      780

ucgaaacucu gguugauauu uuccaagagu acccagacga aauagaguau aucuuuaaac      840

ccucaugugu gccgcucaug cgcugcggcg guuguugcaa cgaugagggg uuagaaugug      900

ucccuaccga ggaaagcaau auuacaaugc agaucaugag aauuaagccc caucagggcc      960

agcacaucgg agagaugagu uuccugcaac auaacaagug cgaauguagg ccuaaaaagg     1020

accgggcccg ccaggagaaa aagucuguga gaggcaaagg gaagggacag aagaggaaac     1080

guaagaaauc ccgguacaag agcuggucgg uguaugucgg ugcucgaugc ugucuuaugc     1140

cauggucuuu gcccggccca caccccugcg ggccuugcuc cgagagaagg aaacaccugu     1200

uuguucaaga uccacagacc uguaagugcu cauguaaaaa uacugacagu cgcugcaagg     1260

cccggcagcu agaacucaac gagagaacau guaggugcga uaagccgcgc cgaugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6593
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt3)

<400>  6593
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggucc cuugcccugu      120

uguuauaccu gcaucacgcu aaguggucuc aggcagcccc cauggcggag ggcgggggac      180

aaaaucauca cgaagucguu aaauuuaugg acguguauca gagaucauac ugccauccua      240

ucgagacccu aguagauauu uuccaggaau auccagacga gauagaauac aucuuuaagc      300

cgaguugugu gccccucaug aggugcggug gcuguugcaa cgaugagggg cuggagugug      360

ucccuacaga agagagcaau auuacuaugc agaucaugcg gauuaaacca caccaaggac      420

agcacaucgg cgaaaugucc uuccuucagc auaacaagug cgagugucgc cccaaaaagg      480

accgagcucg ucaggagaag aaaucuguga gagguaaggg gaaaggacaa aagaggaaac      540

ggaagaaguc gcgcuauaaa ucauggagcg uuuacguggg cgccagaugc ugucugaugc      600

cuuggaguuu gccaggcccc cacccuugcg ggccauguuc cgaaaggcgg aagcaucucu      660

uuguccagga uccgcagacg ugcaaaugcu cuuguaagaa uaccgacagc cgcugcaaag      720

cacgacagcu ggagcugaac gaaagaacau guaggugcga uaagccccgg cguugaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  6594
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt3)

<400>  6594
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcccccugc ucagaaggcu ucuguuggcc gcuuuacugc      120

agcuagcccc ugcacaagcg ccaguguccc agccggacgc ucccggccac cagcggaagg      180

ucguuucuug gaucgaugug uacacccgcg ccacaugcca gccucgagag guaguggucc      240

cacucacugu ggaacugaug gggacgguug caaaacaacu ugugcccuca ugugucaccg      300

ugcagcguug cggagguugu ugcccugacg auggccugga guguguacca acagggcagc      360

aucagguuag aaugcaaauu uugaugauaa gguaucccag uagccagcuc ggagaaaugu      420

cccuggagga acacucucag ugcgaguguc ggccuaagaa aaaggacucg gccgugaaac      480

cagaucgcgc ugcaacuccg caucacagac cccagccuag gucaguccca ggcugggaca      540

gcgcccccgg ugcuccuagu ccagccgaua ucacccaucc cacaccggcg ccugggcccu      600

ccgcacacgc cgcuccaucu accacuagcg cccugacacc uggacccgca gcugccgcgg      660

ccgacgcagc ugccuccuca guggcuaagg gcggcgccug aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  6595
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt3)

<400>  6595
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuucucg gcuucuuuag cguggccugc ucccuucugg      120

cugcagccuu guuacccggg ccuagagagg cgccagcugc cgcagccgcu uucgaaucug      180

gacuggaccu aucagaugca gagccggacg ccggugaagc uaccgccuac gcgaguaagg      240

aucucgagga acagcugagg agcgucuccu cuguugacga gcuuaugaca gugcuguauc      300

ccgaguacug gaaaauguau aagugucaau ugcggaaagg cggguggcag cauaaccgcg      360

aacaggcaaa ucucaacucg cgaacugagg aaacgaucaa guuugccgcu gcccacuaca      420

auaccgagau ucugaaauca auagauaacg aguggcguaa gacacagugc augccuagag      480

aaguauguau cgacguggga aaggaguucg gcgucgcaac uaauaccuuu uucaaaccac      540

ccugcgugag cguuuauagg uguggugggu gcuguaacag ugaaggacug caaugcauga      600

auacauccac cucuuaccuc agcaagacuu uauuugagau uacagugccu cugucccagg      660

gcccaaaacc cgucaccauc ucauucgcua accauacgag uugucggugc augagcaagc      720

uggaugugua ucgccaggua cacucuauua ucagaagguc cuugccugcc acucugccac      780

agugucaagc ggccaauaaa accugcccga caaacuacau guggaauaac cauauaugcc      840

ggugucuagc acaggaagac uuuauguucu caagcgaugc uggcgacgau aguacugacg      900

gguuucacga uaucugcgga cccaauaagg agcucgacga ggaaaccugu cagugcguuu      960

gucgcgccgg ucugcgaccu gcuucuugcg gcccacacaa ggagcuugac agaaacuccu     1020

gucagugcgu guguaaaaau aagcuguucc ccagccaaug cggggccaac agggaauuug     1080

augagaacac augucagugc gucugcaaac ggaccugucc ucguaaucag ccauugaacc     1140

ccggaaagug cgcaugugaa ugcacggagu cgccgcaaaa augucuccug aagggcaaaa     1200

aguuccauca ccagacuugc ucuuguuacc gcagaccuug cacaaauagg cagaaggccu     1260

gugagcccgg uuucuccuau ucagaagagg ugugccggug ugugccaagu uacuggaaac     1320

gaccucagau gagcugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  6596
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt3)

<400>  6596
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagagu ggguggucgu uaacguguuc augaugcugu      120

auguacagcu cgugcaaggc agcuccaaug aacacgggcc cgucaagagg ucuucacaga      180

guacccuuga gcggagcgaa cagcagaucc gcgccgcuuc cucucuggag gaauuguuac      240

gaauuacaca uucggaggac uggaaacugu ggcguugcag acuaaggcuc aagucauuua      300

cuagcaugga uagucggucc gcaucucacc gcagcacgag auucgccgcg accuuuuacg      360

acauagagac acugaaagug aucgaugaag aguggcaaag gacucagugu uccccucggg      420

aaaccugcgu ugagguggcu ucagagcuug gaaagaguac aaacaccuuc uuuaaaccac      480

cgugugucaa uguguuccgc ugcgguggcu guugcaacga agagagccug auuuguauga      540

auacuucuac auccuauauc ucaaagcagu uguuugaaau uagcguaccc cucaccagug      600

uuccugagcu ggugccaguc aagguggcca accauacggg gugcaaaugu cugcccacug      660

caccucgaca cccauacucu aucauaagaa gguccaucca gauucccgaa gaggaccggu      720

gcagccauuc gaagaaacuc uguccuaucg auauguuaug ggacucuaau aagugcaaau      780

gcgugcugca agaggaaaac ccacuugccg gaaccgagga ucacucccac uugcaggaac      840

cggcucugug uggcccccau augauguucg acgaggaucg uugcgaaugu gucugcaaga      900

caccuugucc aaaggaccua auucagcacc ccaaaaauug cucauguuuu gagugcaagg      960

agagucucga aacuuguugc cagaaacaua agcuguucca cccugauacc uguagcugcg     1020

aggaccgcug cccauuucac acaagacccu gugcauccgg uaaaaccgcc ugcgcuaagc     1080

auuguagguu cccgaaagaa aagcgggccg cgcaagggcc ucacucucga aagaaccccu     1140

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  6597
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt4)

<400>  6597
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgacg agaccggcuu cgagcacagc ggccuguggg      120

ugagcgugcu ggccggccug cugcugggcg ccugccaggc ccaccccauc cccgacagca      180

gcccccugcu gcaguucggc ggccagguga gacagagaua ccuguacacc gacgacgccc      240

agcagaccga ggcccaccug gagaucagag aggacggcac cgugggcggc gccgccgacc      300

agagccccga gagccugcug cagcugaagg cccugaagcc cggcgugauc cagauccugg      360

gcgugaagac cagcagauuc cugugccaga gacccgacgg cgcccuguac ggcagccugc      420

acuucgaccc cgaggccugc agcuucagag agcugcugcu ggaggacggc uacaacgugu      480

accagagcga ggcccacggc cugccccugc accugcccgg caacaagagc ccccacagag      540

accccgcccc cagaggcccc gccagauucc ugccccugcc cggccugccc cccgcccugc      600

ccgagccccc cggcauccug gccccccagc cccccgacgu gggcagcagc gacccccuga      660

gcaugguggg ccccagccag ggcagaagcc ccagcuacgc cagcugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  6598
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt4)

<400>  6598
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuucc ccccccugcu gcugcugcug uucuggggcg      120

uggugagcca cagcuucccc gccacccugg agacccagga gcaggacgug gaccuggugc      180

agaaguaccu ggagaaguac uacaaccuga agaacgacgg cagacaggug gagaagagaa      240

gaaacagcgg ccccguggug gagaagcuga agcagaugca ggaguucuuc ggccugaagg      300

ugaccggcaa gcccgacgcc gagacccuga aggugaugaa gcagcccaga ugcggcgugc      360

ccgacguggc ccaguucgug cugaccgagg gcaaccccag augggagcag acccaccuga      420

ccuacagaau cgagaacuac acccccgacc ugcccagagc cgacguggac cacgccaucg      480

agaaggccuu ccagcugugg agcaacguga ccccccugac cuucaccaag gugagcgagg      540

gccaggccga caucaugauc agcuucguga gaggcgacca cagagacaac agccccuucg      600

acggccccgg cggcaaccug gcccacgccu uccagcccgg ccccggcauc ggcggcgacg      660

cccacuucga cgaggacgag agauggacca acaacuucag agaguacaac cugcacagag      720

uggccgccca cgagcugggc cacagccugg gccugagcca cagcaccgac aucggcgccc      780

ugauguaccc cagcuacacc uucagcggcg acgugcagcu ggcccaggac gacaucgacg      840

gcauccaggc caucuacggc agaagccaga accccgugca gcccaucggc ccccagaccc      900

ccaaggccug cgacagcaag cugaccuucg acgccaucac caccaucaga ggcgagguga      960

uguucuucaa ggacagauuc uacaugagaa ccaaccccuu cuaccccgag guggagcuga     1020

acuucaucag cguguucugg ccccagcugc ccaacggccu ggaggccgcc uacgaguucg     1080

ccgacagaga cgaggugaga uucuucaagg gcaacaagua cugggccgug cagggccaga     1140

acgugcugca cggcuacccc aaggacaucu acagcagcuu cggcuucccc agaaccguga     1200

agcacaucga cgccgcccug agcgaggaga acaccggcaa gaccuacuuc uucguggcca     1260

acaaguacug gagauacgac gaguacaaga gaagcaugga ccccggcuac cccaagauga     1320

ucgcccacga cuuccccggc aucggccaca agguggacgc cguguucaug aaggacggcu     1380

ucuucuacuu cuuccacggc accagacagu acaaguucga ccccaagacc aagagaaucc     1440

ugacccugca gaaggccaac agcugguuca acugcagaaa gaacugagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  6599
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt4)

<400>  6599
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuucc ccccccugcu gcugcugcug uucuggggcg      120

uggugagcca cagcuucgug cugaccgagg gcaaccccag augggagcag acccaccuga      180

ccuacagaau cgagaacuac acccccgacc ugcccagagc cgacguggac cacgccaucg      240

agaaggccuu ccagcugugg agcaacguga ccccccugac cuucaccaag gugagcgagg      300

gccaggccga caucaugauc agcuucguga gaggcgacca cagagacaac agccccuucg      360

acggccccgg cggcaaccug gcccacgccu uccagcccgg ccccggcauc ggcggcgacg      420

cccacuucga cgaggacgag agauggacca acaacuucag agaguacaac cugcacagag      480

uggccgccca cgagcugggc cacagccugg gccugagcca cagcaccgac aucggcgccc      540

ugauguaccc cagcuacacc uucagcggcg acgugcagcu ggcccaggac gacaucgacg      600

gcauccaggc caucuacggc agaagccaga accccgugca gcccaucggc ccccagaccc      660

ccaaggccug cgacagcaag cugaccuucg acgccaucac caccaucaga ggcgagguga      720

uguucuucaa ggacagauuc uacaugagaa ccaaccccuu cuaccccgag guggagcuga      780

acuucaucag cguguucugg ccccagcugc ccaacggccu ggaggccgcc uacgaguucg      840

ccgacagaga cgaggugaga uucuucaagg gcaacaagua cugggccgug cagggccaga      900

acgugcugca cggcuacccc aaggacaucu acagcagcuu cggcuucccc agaaccguga      960

agcacaucga cgccgcccug agcgaggaga acaccggcaa gaccuacuuc uucguggcca     1020

acaaguacug gagauacgac gaguacaaga gaagcaugga ccccggcuac cccaagauga     1080

ucgcccacga cuuccccggc aucggccaca agguggacgc cguguucaug aaggacggcu     1140

ucuucuacuu cuuccacggc accagacagu acaaguucga ccccaagacc aagagaaucc     1200

ugacccugca gaaggccaac agcugguuca acugcagaaa gaacugagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  6600
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt4)

<400>  6600
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaagaaca uccugaagau ccugauggac agcuacagca      120

aggagagcaa gauccagacc gugagaagag ugaccagcgu gagccugcug gccguguacc      180

ugaccaugaa caccagcagc cuggugcugg ccaagcccau cgagaacacc aacgacacca      240

gcaucaagaa cguggagaag cugagaaacg cccccaacga ggagaacagc aagaaggugg      300

aggacagcaa gaacgacaag guggagcacg ugaagaacau cgaggaggcc aagguggagc      360

agguggcccc cgaggugaag agcaagagca cccugagaag cgccagcauc gccaacacca      420

acagcgagaa guacgacuuc gaguaccuga acggccugag cuacaccgag cugaccaacc      480

ugaucaagaa caucaagugg aaccagauca acggccuguu caacuacagc accggcagcc      540

agaaguucuu cggcgacaag aacagagugc aggccaucau caacgcccug caggagagcg      600

gcagaaccua caccgccaac gacaugaagg gcaucgagac cuucaccgag gugcugagag      660

ccggcuucua ccugggcuac uacaacgacg gccugagcua ccugaacgac agaaacuucc      720

aggacaagug cauccccgcc augaucgcca uccagaagaa ccccaacuuc aagcugggca      780

ccgccgugca ggacgaggug aucaccagcc ugggcaagcu gaucggcaac gccagcgcca      840

acgccgaggu ggugaacaac ugcgugcccg ugcugaagca guucagagag aaccugaacc      900

aguacgcccc cgacuacgug aagggcaccg ccgugaacga gcugaucaag ggcaucgagu      960

ucgacuucag cggcgccgcc uacgagaagg acgugaagac caugcccugg uacggcaaga     1020

ucgaccccuu caucaacgag cugaaggccc ugggccugua cggcaacauc accagcgcca     1080

ccgagugggc cagcgacgug ggcaucuacu accugagcaa guucggccug uacagcacca     1140

acagaaacga caucgugcag agccuggaga aggccgugga cauguacaag uacggcaaga     1200

ucgccuucgu ggccauggag agaaucaccu gggacuacga cggcaucggc agcaacggca     1260

agaaggugga ccacgacaag uuccuggacg acgccgagaa gcacuaccug cccaagaccu     1320

acaccuucga caacggcacc uucaucauca gagccggcga caaggugagc gaggagaaga     1380

ucaagagacu guacugggcc agcagagagg ugaagagcca guuccacaga guggugggca     1440

acgacaaggc ccuggaggug ggcaacgccg acgacgugcu gaccaugaag aucuucaaca     1500

gccccgagga guacaaguuc aacaccaaca ucaacggcgu gagcaccgac aacggcggcc     1560

uguacaucga gcccagaggc accuucuaca ccuacgagag aaccccccag cagagcaucu     1620

ucagccugga ggagcuguuc agacacgagu acacccacua ccugcaggcc agauaccugg     1680

uggacggccu guggggccag ggccccuucu acgagaagaa cagacugacc ugguucgacg     1740

agggcaccgc cgaguucuuc gccggcagca ccagaaccag cggcgugcug cccagaaaga     1800

gcauccuggg cuaccuggcc aaggacaagg uggaccacag auacagccug aagaagaccc     1860

ugaacagcgg cuacgacgac agcgacugga uguucuacaa cuacggcuuc gccguggccc     1920

acuaccugua cgagaaggac augcccaccu ucaucaagau gaacaaggcc auccugaaca     1980

ccgacgugaa gagcuacgac gagaucauca agaagcugag cgacgacgcc aacaagaaca     2040

ccgaguacca gaaccacauc caggagcugg ccgacaagua ccagggcgcc ggcauccccc     2100

uggugagcga cgacuaccug aaggaccacg gcuacaagaa ggccagcgag guguacagcg     2160

agaucagcaa ggccgccagc cugaccaaca ccagcgugac cgccgagaag agccaguacu     2220

ucaacaccuu cacccugaga ggcaccuaca ccggcgagac cagcaagggc gaguucaagg     2280

acugggacga gaugagcaag aagcuggacg gcacccugga gagccuggcc aagaacagcu     2340

ggagcggcua caagacccug accgccuacu ucaccaacua cagagugacc agcgacaaca     2400

aggugcagua cgacguggug uuccacggcg ugcugaccga caacgccgac aucagcaaca     2460

acaaggcccc caucgccaag gugaccggcc ccagcaccgg cgccgugggc agaaacaucg     2520

aguucagcgg caaggacagc aaggacgagg acggcaagau cgugagcuac gacugggacu     2580

ucggcgacgg cgccaccagc agaggcaaga acagcgugca cgccuacaag aaggccggca     2640

ccuacaacgu gacccugaag gugaccgacg acaagggcgc caccgccacc gagagcuuca     2700

ccaucgagau caagaacgag gacaccacca cccccaucac caaggagaug gagcccaacg     2760

acgacaucaa ggaggccaac ggccccaucg uggagggcgu gaccgugaag ggcgaccuga     2820

acggcagcga cgacgccgac accuucuacu ucgacgugaa ggaggacggc gacgugacca     2880

ucgagcugcc cuacagcggc agcagcaacu ucaccuggcu gguguacaag gagggcgacg     2940

accagaacca caucgccagc ggcaucgaca agaacaacag caaggugggc accuucaaga     3000

gcaccaaggg cagacacuac guguucaucu acaagcacga cagcgccagc aacaucagcu     3060

acagccugaa caucaagggc cugggcaacg agaagcugaa ggagaaggag aacaacgaca     3120

gcagcgacaa ggccaccgug auccccaacu ucaacaccac caugcagggc agccugcugg     3180

gcgacgacag cagagacuac uacagcuucg aggugaagga ggagggcgag gugaacaucg     3240

agcuggacaa gaaggacgag uucggcguga ccuggacccu gcaccccgag agcaacauca     3300

acgacagaau caccuacggc cagguggacg gcaacaaggu gagcaacaag gugaagcuga     3360

gacccggcaa guacuaccug cugguguaca aguacagcgg cagcggcaac uacgagcuga     3420

gagugaacaa gugaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  6601
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt4)

<400>  6601
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcuguuc cuguucagca      120

gcgccuacag caucgccaac accaacagcg agaaguacga cuucgaguac cugaacggcc      180

ugagcuacac cgagcugacc aaccugauca agaacaucaa guggaaccag aucaacggcc      240

uguucaacua cagcaccggc agccagaagu ucuucggcga caagaacaga gugcaggcca      300

ucaucaacgc ccugcaggag agcggcagaa ccuacaccgc caacgacaug aagggcaucg      360

agaccuucac cgaggugcug agagccggcu ucuaccuggg cuacuacaac gacggccuga      420

gcuaccugaa cgacagaaac uuccaggaca agugcauccc cgccaugauc gccauccaga      480

agaaccccaa cuucaagcug ggcaccgccg ugcaggacga ggugaucacc agccugggca      540

agcugaucgg caacgccagc gccaacgccg agguggugaa caacugcgug cccgugcuga      600

agcaguucag agagaaccug aaccaguacg cccccgacua cgugaagggc accgccguga      660

acgagcugau caagggcauc gaguucgacu ucagcggcgc cgccuacgag aaggacguga      720

agaccaugcc cugguacggc aagaucgacc ccuucaucaa cgagcugaag gcccugggcc      780

uguacggcaa caucaccagc gccaccgagu gggccagcga cgugggcauc uacuaccuga      840

gcaaguucgg ccuguacagc accaacagaa acgacaucgu gcagagccug gagaaggccg      900

uggacaugua caaguacggc aagaucgccu ucguggccau ggagagaauc accugggacu      960

acgacggcau cggcagcaac ggcaagaagg uggaccacga caaguuccug gacgacgccg     1020

agaagcacua ccugcccaag accuacaccu ucgacaacgg caccuucauc aucagagccg     1080

gcgacaaggu gagcgaggag aagaucaaga gacuguacug ggccagcaga gaggugaaga     1140

gccaguucca cagaguggug ggcaacgaca aggcccugga ggugggcaac gccgacgacg     1200

ugcugaccau gaagaucuuc aacagccccg aggaguacaa guucaacacc aacaucaacg     1260

gcgugagcac cgacaacggc ggccuguaca ucgagcccag aggcaccuuc uacaccuacg     1320

agagaacccc ccagcagagc aucuucagcc uggaggagcu guucagacac gaguacaccc     1380

acuaccugca ggccagauac cugguggacg gccugugggg ccagggcccc uucuacgaga     1440

agaacagacu gaccugguuc gacgagggca ccgccgaguu cuucgccggc agcaccagaa     1500

ccagcggcgu gcugcccaga aagagcaucc ugggcuaccu ggccaaggac aagguggacc     1560

acagauacag ccugaagaag acccugaaca gcggcuacga cgacagcgac uggauguucu     1620

acaacuacgg cuucgccgug gcccacuacc uguacgagaa ggacaugccc accuucauca     1680

agaugaacaa ggccauccug aacaccgacg ugaagagcua cgacgagauc aucaagaagc     1740

ugagcgacga cgccaacaag aacaccgagu accagaacca cauccaggag cuggccgaca     1800

aguaccaggg cgccggcauc ccccugguga gcgacgacua ccugaaggac cacggcuaca     1860

agaaggccag cgagguguac agcgagauca gcaaggccgc cagccugacc aacaccagcg     1920

ugaccgccga gaagagccag uacuucaaca ccuucacccu gagaggcacc uacaccggcg     1980

agaccagcaa gggcgaguuc aaggacuggg acgagaugag caagaagcug gacggcaccc     2040

uggagagccu ggccaagaac agcuggagcg gcuacaagac ccugaccgcc uacuucacca     2100

acuacagagu gaccagcgac aacaaggugc aguacgacgu gguguuccac ggcgugcuga     2160

ccgacaacgc cgacaucagc aacaacaagg cccccaucgc caaggugacc ggccccagca     2220

ccggcgccgu gggcagaaac aucgaguuca gcggcaagga cagcaaggac gaggacggca     2280

agaucgugag cuacgacugg gacuucggcg acggcgccac cagcagaggc aagaacagcg     2340

ugcacgccua caagaaggcc ggcaccuaca acgugacccu gaaggugacc gacgacaagg     2400

gcgccaccgc caccgagagc uucaccaucg agaucaagaa cgaggacacc accaccccca     2460

ucaccaagga gauggagccc aacgacgaca ucaaggaggc caacggcccc aucguggagg     2520

gcgugaccgu gaagggcgac cugaacggca gcgacgacgc cgacaccuuc uacuucgacg     2580

ugaaggagga cggcgacgug accaucgagc ugcccuacag cggcagcagc aacuucaccu     2640

ggcuggugua caaggagggc gacgaccaga accacaucgc cagcggcauc gacaagaaca     2700

acagcaaggu gggcaccuuc aagagcacca agggcagaca cuacguguuc aucuacaagc     2760

acgacagcgc cagcaacauc agcuacagcc ugaacaucaa gggccugggc aacgagaagc     2820

ugaaggagaa ggagaacaac gacagcagcg acaaggccac cgugaucccc aacuucaaca     2880

ccaccaugca gggcagccug cugggcgacg acagcagaga cuacuacagc uucgagguga     2940

aggaggaggg cgaggugaac aucgagcugg acaagaagga cgaguucggc gugaccugga     3000

cccugcaccc cgagagcaac aucaacgaca gaaucaccua cggccaggug gacggcaaca     3060

aggugagcaa caaggugaag cugagacccg gcaaguacua ccugcuggug uacaaguaca     3120

gcggcagcgg caacuacgag cugagaguga acaagugagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  6602
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt4)

<400>  6602
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcuguuc cuguucagca      120

gcgccuacag caugaagaag aacauccuga agauccugau ggacagcuac agcaaggaga      180

gcaagaucca gaccgugaga agagugacca gcgugagccu gcuggccgug uaccugacca      240

ugaacaccag cagccuggug cuggccaagc ccaucgagaa caccaacgac accagcauca      300

agaacgugga gaagcugaga aacgccccca acgaggagaa cagcaagaag guggaggaca      360

gcaagaacga caagguggag cacgugaaga acaucgagga ggccaaggug gagcaggugg      420

cccccgaggu gaagagcaag agcacccuga gaagcgccag cagaagaaga agaaagagaa      480

ucgccaacac caacagcgag aaguacgacu ucgaguaccu gaacggccug agcuacaccg      540

agcugaccaa ccugaucaag aacaucaagu ggaaccagau caacggccug uucaacuaca      600

gcaccggcag ccagaaguuc uucggcgaca agaacagagu gcaggccauc aucaacgccc      660

ugcaggagag cggcagaacc uacaccgcca acgacaugaa gggcaucgag accuucaccg      720

aggugcugag agccggcuuc uaccugggcu acuacaacga cggccugagc uaccugaacg      780

acagaaacuu ccaggacaag ugcauccccg ccaugaucgc cauccagaag aaccccaacu      840

ucaagcuggg caccgccgug caggacgagg ugaucaccag ccugggcaag cugaucggca      900

acgccagcgc caacgccgag guggugaaca acugcgugcc cgugcugaag caguucagag      960

agaaccugaa ccaguacgcc cccgacuacg ugaagggcac cgccgugaac gagcugauca     1020

agggcaucga guucgacuuc agcggcgccg ccuacgagaa ggacgugaag accaugcccu     1080

gguacggcaa gaucgacccc uucaucaacg agcugaaggc ccugggccug uacggcaaca     1140

ucaccagcgc caccgagugg gccagcgacg ugggcaucua cuaccugagc aaguucggcc     1200

uguacagcac caacagaaac gacaucgugc agagccugga gaaggccgug gacauguaca     1260

aguacggcaa gaucgccuuc guggccaugg agagaaucac cugggacuac gacggcaucg     1320

gcagcaacgg caagaaggug gaccacgaca aguuccugga cgacgccgag aagcacuacc     1380

ugcccaagac cuacaccuuc gacaacggca ccuucaucau cagagccggc gacaagguga     1440

gcgaggagaa gaucaagaga cuguacuggg ccagcagaga ggugaagagc caguuccaca     1500

gagugguggg caacgacaag gcccuggagg ugggcaacgc cgacgacgug cugaccauga     1560

agaucuucaa cagccccgag gaguacaagu ucaacaccaa caucaacggc gugagcaccg     1620

acaacggcgg ccuguacauc gagcccagag gcaccuucua caccuacgag agaacccccc     1680

agcagagcau cuucagccug gaggagcugu ucagacacga guacacccac uaccugcagg     1740

ccagauaccu gguggacggc cuguggggcc agggccccuu cuacgagaag aacagacuga     1800

ccugguucga cgagggcacc gccgaguucu ucgccggcag caccagaacc agcggcgugc     1860

ugcccagaaa gagcauccug ggcuaccugg ccaaggacaa gguggaccac agauacagcc     1920

ugaagaagac ccugaacagc ggcuacgacg acagcgacug gauguucuac aacuacggcu     1980

ucgccguggc ccacuaccug uacgagaagg acaugcccac cuucaucaag augaacaagg     2040

ccauccugaa caccgacgug aagagcuacg acgagaucau caagaagcug agcgacgacg     2100

ccaacaagaa caccgaguac cagaaccaca uccaggagcu ggccgacaag uaccagggcg     2160

ccggcauccc ccuggugagc gacgacuacc ugaaggacca cggcuacaag aaggccagcg     2220

agguguacag cgagaucagc aaggccgcca gccugaccaa caccagcgug accgccgaga     2280

agagccagua cuucaacacc uucacccuga gaggcaccua caccggcgag accagcaagg     2340

gcgaguucaa ggacugggac gagaugagca agaagcugga cggcacccug gagagccugg     2400

ccaagaacag cuggagcggc uacaagaccc ugaccgccua cuucaccaac uacagaguga     2460

ccagcgacaa caaggugcag uacgacgugg uguuccacgg cgugcugacc gacaacgccg     2520

acaucagcaa caacaaggcc cccaucgcca aggugaccgg ccccagcacc ggcgccgugg     2580

gcagaaacau cgaguucagc ggcaaggaca gcaaggacga ggacggcaag aucgugagcu     2640

acgacuggga cuucggcgac ggcgccacca gcagaggcaa gaacagcgug cacgccuaca     2700

agaaggccgg caccuacaac gugacccuga aggugaccga cgacaagggc gccaccgcca     2760

ccgagagcuu caccaucgag aucaagaacg aggacaccac cacccccauc accaaggaga     2820

uggagcccaa cgacgacauc aaggaggcca acggccccau cguggagggc gugaccguga     2880

agggcgaccu gaacggcagc gacgacgccg acaccuucua cuucgacgug aaggaggacg     2940

gcgacgugac caucgagcug cccuacagcg gcagcagcaa cuucaccugg cugguguaca     3000

aggagggcga cgaccagaac cacaucgcca gcggcaucga caagaacaac agcaaggugg     3060

gcaccuucaa gagcaccaag ggcagacacu acguguucau cuacaagcac gacagcgcca     3120

gcaacaucag cuacagccug aacaucaagg gccugggcaa cgagaagcug aaggagaagg     3180

agaacaacga cagcagcgac aaggccaccg ugauccccaa cuucaacacc accaugcagg     3240

gcagccugcu gggcgacgac agcagagacu acuacagcuu cgaggugaag gaggagggcg     3300

aggugaacau cgagcuggac aagaaggacg aguucggcgu gaccuggacc cugcaccccg     3360

agagcaacau caacgacaga aucaccuacg gccaggugga cggcaacaag gugagcaaca     3420

aggugaagcu gagacccggc aaguacuacc ugcuggugua caaguacagc ggcagcggca     3480

acuacgagcu gagagugaac aagugaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  6603
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt4)

<400>  6603
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuga agaucauccu gaacagaggc aagaccauga      120

agagaaagug ccugagcaag agacugaugc uggccaucac cauggccacc aucuucaccg      180

ugaacagcac ccugcccauc uacgccgccg uggacaagaa caacgccacc gccgccgugc      240

agaacgagag caagagauac accgugagcu accugaagac ccugaacuac uacgaccugg      300

uggaccugcu ggugaagacc gagaucgaga accugcccga ccuguuccag uacagcagcg      360

acgccaagga guucuacggc aacaagacca gaaugagcuu caucauggac gagaucggca      420

gaagagcccc ccaguacacc gagaucgacc acaagggcau ccccacccug guggaggugg      480

ugagagccgg cuucuaccug ggcuuccaca acaaggagcu gaacgagauc aacaagagaa      540

gcuucaagga gagagugauc cccagcaucc uggccaucca gaagaacccc aacuucaagc      600

ugggcaccga ggugcaggac aagaucguga gcgccaccgg ccugcuggcc ggcaacgaga      660

ccgccccccc cgagguggug aacaacuuca cccccauccu gcaggacugc aucaagaaca      720

ucgacagaua cgcccuggac gaccugaaga gcaaggcccu guucaacgug cuggccgccc      780

ccaccuacga caucaccgag uaccugagag ccaccaagga gaagcccgag aacacccccu      840

gguacggcaa gaucgacggc uucaucaacg agcugaagaa gcuggcccug uacggcaaga      900

ucaacgacaa caacagcugg aucaucgaca acggcaucua ccacaucgcc ccccugggca      960

agcugcacag caacaacaag aucggcaucg agacccugac cgaggugaug aagguguacc     1020

ccuaccugag caugcagcac cugcagagcg ccgaccagau caagagacac uacgacagca     1080

aggacgccga gggcaacaag aucccccugg acaaguucaa gaaggagggc aaggagaagu     1140

acugccccaa gaccuacacc uucgacgacg gcaaggugau caucaaggcc ggcgccagag     1200

uggaggagga gaaggugaag agacuguacu gggccagcaa ggaggugaac agccaguucu     1260

ucagagugua cggcaucgac aagccccugg aggagggcaa ccccgacgac auccugacca     1320

uggugaucua caacagcccc gaggaguaca agcugaacag cgugcuguac ggcuacgaca     1380

ccaacaacgg cggcauguac aucgagcccg agggcaccuu cuucaccuac gagagagagg     1440

cccaggagag caccuacacc cuggaggagc uguucagaca cgaguacacc cacuaccugc     1500

agggcagaua cgccgugccc ggccaguggg gcagaaccaa gcuguacgac aacgacagac     1560

ugaccuggua cgaggagggc ggcgccgagc uguucgccgg cagcaccaga accagcggca     1620

uccugcccag aaagagcauc gugagcaaca uccacaacac caccagaaac aacagauaca     1680

agcugagcga caccgugcac agcaaguacg gcgccagcuu cgaguucuac aacuacgccu     1740

gcauguucau ggacuacaug uacaacaagg acaugggcau ccugaacaag cugaacgacc     1800

uggccaagaa caacgacgug gacggcuacg acaacuacau cagagaccug agcagcaacu     1860

acgcccugaa cgacaaguac caggaccaca ugcaggagag aaucgacaac uacgagaacc     1920

ugaccgugcc cuucguggcc gacgacuacc uggugagaca cgccuacaag aaccccaacg     1980

agaucuacag cgagaucagc gagguggcca agcugaagga cgccaagagc gaggugaaga     2040

agagccagua cuucagcacc uucacccuga gaggcagcua caccggcggc gccagcaagg     2100

gcaagcugga ggaccagaag gccaugaaca aguucaucga cgacagccug aagaagcugg     2160

acaccuacag cuggagcggc uacaagaccc ugaccgccua cuucaccaac uacaaggugg     2220

acagcagcaa cagagugacc uacgacgugg uguuccacgg cuaccugccc aacgagggcg     2280

acagcaagaa cagccugccc uacggcaaga ucaacggcac cuacaagggc accgagaagg     2340

agaagaucaa guucagcagc gagggcagcu ucgaccccga cggcaagauc gugagcuacg     2400

agugggacuu cggcgacggc aacaagagca acgaggagaa ccccgagcac agcuacgaca     2460

aggugggcac cuacaccgug aagcugaagg ugaccgacga caagggcgag agcagcguga     2520

gcaccaccac cgccgagauc aaggaccuga gcgagaacaa gcugcccgug aucuacaugc     2580

acgugcccaa gagcggcgcc cugaaccaga aggugguguu cuacggcaag ggcaccuacg     2640

accccgacgg cagcaucgcc ggcuaccagu gggacuucgg cgacggcagc gacuucagca     2700

gcgagcagaa ccccagccac guguacacca agaagggcga guacaccgug acccugagag     2760

ugauggacag cagcggccag augagcgaga agaccaugaa gaucaagauc accgaccccg     2820

uguaccccau cggcaccgag aaggagccca acaacagcaa ggagaccgcc agcggcccca     2880

ucgugcccgg cauccccgug agcggcacca ucgagaacac cagcgaccag gacuacuucu     2940

acuucgacgu gaucaccccc ggcgagguga agaucgacau caacaagcug ggcuacggcg     3000

gcgccaccug ggugguguac gacgagaaca acaacgccgu gagcuacgcc accgacgacg     3060

gccagaaccu gagcggcaag uucaaggccg acaagcccgg cagauacuac auccaccugu     3120

acauguucaa cggcagcuac augcccuaca gaaucaacau cgagggcagc gugggcagau     3180

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  6604
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt4)

<400>  6604
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagagaaagu gccugagcaa gagacugaug cuggccauca      120

ccauggccac caucuucacc gugaacagca cccugcccau cuacgccgcc guggacaaga      180

acaacgccac cgccgccgug cagaacgaga gcaagagaua caccgugagc uaccugaaga      240

cccugaacua cuacgaccug guggaccugc uggugaagac cgagaucgag aaccugcccg      300

accuguucca guacagcagc gacgccaagg aguucuacgg caacaagacc agaaugagcu      360

ucaucaugga cgagaucggc agaagagccc cccaguacac cgagaucgac cacaagggca      420

uccccacccu gguggaggug gugagagccg gcuucuaccu gggcuuccac aacaaggagc      480

ugaacgagau caacaagaga agcuucaagg agagagugau ccccagcauc cuggccaucc      540

agaagaaccc caacuucaag cugggcaccg aggugcagga caagaucgug agcgccaccg      600

gccugcuggc cggcaacgag accgcccccc ccgagguggu gaacaacuuc acccccaucc      660

ugcaggacug caucaagaac aucgacagau acgcccugga cgaccugaag agcaaggccc      720

uguucaacgu gcuggccgcc cccaccuacg acaucaccga guaccugaga gccaccaagg      780

agaagcccga gaacaccccc ugguacggca agaucgacgg cuucaucaac gagcugaaga      840

agcuggcccu guacggcaag aucaacgaca acaacagcug gaucaucgac aacggcaucu      900

accacaucgc cccccugggc aagcugcaca gcaacaacaa gaucggcauc gagacccuga      960

ccgaggugau gaagguguac cccuaccuga gcaugcagca ccugcagagc gccgaccaga     1020

ucaagagaca cuacgacagc aaggacgccg agggcaacaa gaucccccug gacaaguuca     1080

agaaggaggg caaggagaag uacugcccca agaccuacac cuucgacgac ggcaagguga     1140

ucaucaaggc cggcgccaga guggaggagg agaaggugaa gagacuguac ugggccagca     1200

aggaggugaa cagccaguuc uucagagugu acggcaucga caagccccug gaggagggca     1260

accccgacga cauccugacc auggugaucu acaacagccc cgaggaguac aagcugaaca     1320

gcgugcugua cggcuacgac accaacaacg gcggcaugua caucgagccc gagggcaccu     1380

ucuucaccua cgagagagag gcccaggaga gcaccuacac ccuggaggag cuguucagac     1440

acgaguacac ccacuaccug cagggcagau acgccgugcc cggccagugg ggcagaacca     1500

agcuguacga caacgacaga cugaccuggu acgaggaggg cggcgccgag cuguucgccg     1560

gcagcaccag aaccagcggc auccugccca gaaagagcau cgugagcaac auccacaaca     1620

ccaccagaaa caacagauac aagcugagcg acaccgugca cagcaaguac ggcgccagcu     1680

ucgaguucua caacuacgcc ugcauguuca uggacuacau guacaacaag gacaugggca     1740

uccugaacaa gcugaacgac cuggccaaga acaacgacgu ggacggcuac gacaacuaca     1800

ucagagaccu gagcagcaac uacgcccuga acgacaagua ccaggaccac augcaggaga     1860

gaaucgacaa cuacgagaac cugaccgugc ccuucguggc cgacgacuac cuggugagac     1920

acgccuacaa gaaccccaac gagaucuaca gcgagaucag cgagguggcc aagcugaagg     1980

acgccaagag cgaggugaag aagagccagu acuucagcac cuucacccug agaggcagcu     2040

acaccggcgg cgccagcaag ggcaagcugg aggaccagaa ggccaugaac aaguucaucg     2100

acgacagccu gaagaagcug gacaccuaca gcuggagcgg cuacaagacc cugaccgccu     2160

acuucaccaa cuacaaggug gacagcagca acagagugac cuacgacgug guguuccacg     2220

gcuaccugcc caacgagggc gacagcaaga acagccugcc cuacggcaag aucaacggca     2280

ccuacaaggg caccgagaag gagaagauca aguucagcag cgagggcagc uucgaccccg     2340

acggcaagau cgugagcuac gagugggacu ucggcgacgg caacaagagc aacgaggaga     2400

accccgagca cagcuacgac aaggugggca ccuacaccgu gaagcugaag gugaccgacg     2460

acaagggcga gagcagcgug agcaccacca ccgccgagau caaggaccug agcgagaaca     2520

agcugcccgu gaucuacaug cacgugccca agagcggcgc ccugaaccag aagguggugu     2580

ucuacggcaa gggcaccuac gaccccgacg gcagcaucgc cggcuaccag ugggacuucg     2640

gcgacggcag cgacuucagc agcgagcaga accccagcca cguguacacc aagaagggcg     2700

aguacaccgu gacccugaga gugauggaca gcagcggcca gaugagcgag aagaccauga     2760

agaucaagau caccgacccc guguacccca ucggcaccga gaaggagccc aacaacagca     2820

aggagaccgc cagcggcccc aucgugcccg gcauccccgu gagcggcacc aucgagaaca     2880

ccagcgacca ggacuacuuc uacuucgacg ugaucacccc cggcgaggug aagaucgaca     2940

ucaacaagcu gggcuacggc ggcgccaccu ggguggugua cgacgagaac aacaacgccg     3000

ugagcuacgc caccgacgac ggccagaacc ugagcggcaa guucaaggcc gacaagcccg     3060

gcagauacua cauccaccug uacauguuca acggcagcua caugcccuac agaaucaaca     3120

ucgagggcag cgugggcaga ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  6605
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt4)

<400>  6605
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcuguuc cuguucagca      120

gcgccuacag cgugcagaac gagagcaaga gauacaccgu gagcuaccug aagacccuga      180

acuacuacga ccugguggac cugcugguga agaccgagau cgagaaccug cccgaccugu      240

uccaguacag cagcgacgcc aaggaguucu acggcaacaa gaccagaaug agcuucauca      300

uggacgagau cggcagaaga gccccccagu acaccgagau cgaccacaag ggcaucccca      360

cccuggugga gguggugaga gccggcuucu accugggcuu ccacaacaag gagcugaacg      420

agaucaacaa gagaagcuuc aaggagagag ugauccccag cauccuggcc auccagaaga      480

accccaacuu caagcugggc accgaggugc aggacaagau cgugagcgcc accggccugc      540

uggccggcaa cgagaccgcc ccccccgagg uggugaacaa cuucaccccc auccugcagg      600

acugcaucaa gaacaucgac agauacgccc uggacgaccu gaagagcaag gcccuguuca      660

acgugcuggc cgcccccacc uacgacauca ccgaguaccu gagagccacc aaggagaagc      720

ccgagaacac ccccugguac ggcaagaucg acggcuucau caacgagcug aagaagcugg      780

cccuguacgg caagaucaac gacaacaaca gcuggaucau cgacaacggc aucuaccaca      840

ucgccccccu gggcaagcug cacagcaaca acaagaucgg caucgagacc cugaccgagg      900

ugaugaaggu guaccccuac cugagcaugc agcaccugca gagcgccgac cagaucaaga      960

gacacuacga cagcaaggac gccgagggca acaagauccc ccuggacaag uucaagaagg     1020

agggcaagga gaaguacugc cccaagaccu acaccuucga cgacggcaag gugaucauca     1080

aggccggcgc cagaguggag gaggagaagg ugaagagacu guacugggcc agcaaggagg     1140

ugaacagcca guucuucaga guguacggca ucgacaagcc ccuggaggag ggcaaccccg     1200

acgacauccu gaccauggug aucuacaaca gccccgagga guacaagcug aacagcgugc     1260

uguacggcua cgacaccaac aacggcggca uguacaucga gcccgagggc accuucuuca     1320

ccuacgagag agaggcccag gagagcaccu acacccugga ggagcuguuc agacacgagu     1380

acacccacua ccugcagggc agauacgccg ugcccggcca guggggcaga accaagcugu     1440

acgacaacga cagacugacc ugguacgagg agggcggcgc cgagcuguuc gccggcagca     1500

ccagaaccag cggcauccug cccagaaaga gcaucgugag caacauccac aacaccacca     1560

gaaacaacag auacaagcug agcgacaccg ugcacagcaa guacggcgcc agcuucgagu     1620

ucuacaacua cgccugcaug uucauggacu acauguacaa caaggacaug ggcauccuga     1680

acaagcugaa cgaccuggcc aagaacaacg acguggacgg cuacgacaac uacaucagag     1740

accugagcag caacuacgcc cugaacgaca aguaccagga ccacaugcag gagagaaucg     1800

acaacuacga gaaccugacc gugcccuucg uggccgacga cuaccuggug agacacgccu     1860

acaagaaccc caacgagauc uacagcgaga ucagcgaggu ggccaagcug aaggacgcca     1920

agagcgaggu gaagaagagc caguacuuca gcaccuucac ccugagaggc agcuacaccg     1980

gcggcgccag caagggcaag cuggaggacc agaaggccau gaacaaguuc aucgacgaca     2040

gccugaagaa gcuggacacc uacagcugga gcggcuacaa gacccugacc gccuacuuca     2100

ccaacuacaa gguggacagc agcaacagag ugaccuacga cgugguguuc cacggcuacc     2160

ugcccaacga gggcgacagc aagaacagcc ugcccuacgg caagaucaac ggcaccuaca     2220

agggcaccga gaaggagaag aucaaguuca gcagcgaggg cagcuucgac cccgacggca     2280

agaucgugag cuacgagugg gacuucggcg acggcaacaa gagcaacgag gagaaccccg     2340

agcacagcua cgacaaggug ggcaccuaca ccgugaagcu gaaggugacc gacgacaagg     2400

gcgagagcag cgugagcacc accaccgccg agaucaagga ccugagcgag aacaagcugc     2460

ccgugaucua caugcacgug cccaagagcg gcgcccugaa ccagaaggug guguucuacg     2520

gcaagggcac cuacgacccc gacggcagca ucgccggcua ccagugggac uucggcgacg     2580

gcagcgacuu cagcagcgag cagaacccca gccacgugua caccaagaag ggcgaguaca     2640

ccgugacccu gagagugaug gacagcagcg gccagaugag cgagaagacc augaagauca     2700

agaucaccga ccccguguac cccaucggca ccgagaagga gcccaacaac agcaaggaga     2760

ccgccagcgg ccccaucgug cccggcaucc ccgugagcgg caccaucgag aacaccagcg     2820

accaggacua cuucuacuuc gacgugauca cccccggcga ggugaagauc gacaucaaca     2880

agcugggcua cggcggcgcc accugggugg uguacgacga gaacaacaac gccgugagcu     2940

acgccaccga cgacggccag aaccugagcg gcaaguucaa ggccgacaag cccggcagau     3000

acuacaucca ccuguacaug uucaacggca gcuacaugcc cuacagaauc aacaucgagg     3060

gcagcguggg cagaugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6606
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt4)

<400>  6606
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcuguuc cuguucagca      120

gcgccuacag caugaagaga aagugccuga gcaagagacu gaugcuggcc aucaccaugg      180

ccaccaucuu caccgugaac agcacccugc ccaucuacgc cgccguggac aagaacaacg      240

ccaccgccgc cagaagaaga agaaagagag ugcagaacga gagcaagaga uacaccguga      300

gcuaccugaa gacccugaac uacuacgacc ugguggaccu gcuggugaag accgagaucg      360

agaaccugcc cgaccuguuc caguacagca gcgacgccaa ggaguucuac ggcaacaaga      420

ccagaaugag cuucaucaug gacgagaucg gcagaagagc cccccaguac accgagaucg      480

accacaaggg cauccccacc cugguggagg uggugagagc cggcuucuac cugggcuucc      540

acaacaagga gcugaacgag aucaacaaga gaagcuucaa ggagagagug auccccagca      600

uccuggccau ccagaagaac cccaacuuca agcugggcac cgaggugcag gacaagaucg      660

ugagcgccac cggccugcug gccggcaacg agaccgcccc ccccgaggug gugaacaacu      720

ucacccccau ccugcaggac ugcaucaaga acaucgacag auacgcccug gacgaccuga      780

agagcaaggc ccuguucaac gugcuggccg cccccaccua cgacaucacc gaguaccuga      840

gagccaccaa ggagaagccc gagaacaccc ccugguacgg caagaucgac ggcuucauca      900

acgagcugaa gaagcuggcc cuguacggca agaucaacga caacaacagc uggaucaucg      960

acaacggcau cuaccacauc gccccccugg gcaagcugca cagcaacaac aagaucggca     1020

ucgagacccu gaccgaggug augaaggugu accccuaccu gagcaugcag caccugcaga     1080

gcgccgacca gaucaagaga cacuacgaca gcaaggacgc cgagggcaac aagauccccc     1140

uggacaaguu caagaaggag ggcaaggaga aguacugccc caagaccuac accuucgacg     1200

acggcaaggu gaucaucaag gccggcgcca gaguggagga ggagaaggug aagagacugu     1260

acugggccag caaggaggug aacagccagu ucuucagagu guacggcauc gacaagcccc     1320

uggaggaggg caaccccgac gacauccuga ccauggugau cuacaacagc cccgaggagu     1380

acaagcugaa cagcgugcug uacggcuacg acaccaacaa cggcggcaug uacaucgagc     1440

ccgagggcac cuucuucacc uacgagagag aggcccagga gagcaccuac acccuggagg     1500

agcuguucag acacgaguac acccacuacc ugcagggcag auacgccgug cccggccagu     1560

ggggcagaac caagcuguac gacaacgaca gacugaccug guacgaggag ggcggcgccg     1620

agcuguucgc cggcagcacc agaaccagcg gcauccugcc cagaaagagc aucgugagca     1680

acauccacaa caccaccaga aacaacagau acaagcugag cgacaccgug cacagcaagu     1740

acggcgccag cuucgaguuc uacaacuacg ccugcauguu cauggacuac auguacaaca     1800

aggacauggg cauccugaac aagcugaacg accuggccaa gaacaacgac guggacggcu     1860

acgacaacua caucagagac cugagcagca acuacgcccu gaacgacaag uaccaggacc     1920

acaugcagga gagaaucgac aacuacgaga accugaccgu gcccuucgug gccgacgacu     1980

accuggugag acacgccuac aagaacccca acgagaucua cagcgagauc agcgaggugg     2040

ccaagcugaa ggacgccaag agcgagguga agaagagcca guacuucagc accuucaccc     2100

ugagaggcag cuacaccggc ggcgccagca agggcaagcu ggaggaccag aaggccauga     2160

acaaguucau cgacgacagc cugaagaagc uggacaccua cagcuggagc ggcuacaaga     2220

cccugaccgc cuacuucacc aacuacaagg uggacagcag caacagagug accuacgacg     2280

ugguguucca cggcuaccug cccaacgagg gcgacagcaa gaacagccug cccuacggca     2340

agaucaacgg caccuacaag ggcaccgaga aggagaagau caaguucagc agcgagggca     2400

gcuucgaccc cgacggcaag aucgugagcu acgaguggga cuucggcgac ggcaacaaga     2460

gcaacgagga gaaccccgag cacagcuacg acaagguggg caccuacacc gugaagcuga     2520

aggugaccga cgacaagggc gagagcagcg ugagcaccac caccgccgag aucaaggacc     2580

ugagcgagaa caagcugccc gugaucuaca ugcacgugcc caagagcggc gcccugaacc     2640

agaagguggu guucuacggc aagggcaccu acgaccccga cggcagcauc gccggcuacc     2700

agugggacuu cggcgacggc agcgacuuca gcagcgagca gaaccccagc cacguguaca     2760

ccaagaaggg cgaguacacc gugacccuga gagugaugga cagcagcggc cagaugagcg     2820

agaagaccau gaagaucaag aucaccgacc ccguguaccc caucggcacc gagaaggagc     2880

ccaacaacag caaggagacc gccagcggcc ccaucgugcc cggcaucccc gugagcggca     2940

ccaucgagaa caccagcgac caggacuacu ucuacuucga cgugaucacc cccggcgagg     3000

ugaagaucga caucaacaag cugggcuacg gcggcgccac cuggguggug uacgacgaga     3060

acaacaacgc cgugagcuac gccaccgacg acggccagaa ccugagcggc aaguucaagg     3120

ccgacaagcc cggcagauac uacauccacc uguacauguu caacggcagc uacaugcccu     3180

acagaaucaa caucgagggc agcgugggca gaugaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  6607
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt4)

<400>  6607
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccugcug ggcgccgccu      120

ucgccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagagca ucagaccccc cuaccccagc uacggcuacg      240

agcccauggg cggcuggcug caccaccaga ucauccccgu gcugagccag cagcaccccc      300

ccacccacac ccugcagccc caccaccaca uccccguggu gcccgcccag cagcccguga      360

ucccccagca gcccaugaug cccgugcccg gccagcacag caugaccccc auccagcacc      420

accagcccaa ccugcccccc cccgcccagc agcccuacca gccccagccc gugcagcccc      480

agccccacca gcccaugcag ccccagcccc ccgugcaccc caugcagccc cugccccccc      540

agcccccccu gccccccaug uuccccaugc agccccugcc ccccaugcug cccgaccuga      600

cccuggaggc cuggcccagc accgacaaga ccaagagaga ggagguggac ugaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  6608
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt4)

<400>  6608
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagag caucagaccc cccuacccca      180

gcuacggcua cgagcccaug ggcggcuggu gaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  6609
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt4)

<400>  6609
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagag caucagaccc ccccccaugc      180

ugcccgaccu gacccuggag gccuggccca gcaccgacaa gaccaagaga gaggaggugg      240

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  6610
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt4)

<400>  6610
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cccccagaac ccuggugcug cugcugagcg      120

gcgcccuggc ccugacccag accugggcca ugccccugcc cccccacccc ggccaccccg      180

gcuacaucaa cuucagcuac gaggugcuga ccccccugaa gugguaccag agcaucagac      240

cccccuaccc cagcuacggc uacgagccca ugggcggcug gugaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  6611
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt4)

<400>  6611
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cccccagaac ccuggugcug cugcugagcg      120

gcgcccuggc ccugacccag accugggcca ugccccugcc cccccacccc ggccaccccg      180

gcuacaucaa cuucagcuac gaggugcuga ccccccugaa gugguaccag agcaucagac      240

ccccccccau gcugcccgac cugacccugg aggccuggcc cagcaccgac aagaccaaga      300

gagaggaggu ggacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  6612
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt4)

<400>  6612
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuggug ggcgccgccu      120

ucgccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagagca ugaucagacc ccccuacagc agcuacggcu      240

acgagcccau gggcggcugg cugcaccacc agaucauccc cguggugagc cagcagcacc      300

cccugaccca cacccugcag agccaccacc acauccccgu ggugcccgcc cagcagccca      360

gagugagaca gcaggcccug augcccgugc ccggccagca gagcaugacc cccacccagc      420

accaccagcc caaccugccc cugcccgccc agcagcccuu ccagccccag cccgugcagc      480

cccagcccca ccagcccaug cagccccagc cccccgugca gcccaugcag ccccugcugc      540

cccagccccc ccugcccccc auguuccccc ugagaccccu gccccccauc cugcccgacc      600

ugcaccugga ggccuggccc gccaccgaca agaccaagca ggaggaggug gacugaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  6613
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt4)

<400>  6613
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagag caugaucaga ccccccuaca      180

gcagcuacgg cuacgagccc augggcggcu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6614
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt4)

<400>  6614
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagag caugaucaga ccccccccca      180

uccugcccga ccugcaccug gaggccuggc ccgccaccga caagaccaag caggaggagg      240

uggacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6615
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt4)

<400>  6615
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cccccagaac ccuggugcug cugcugagcg      120

gcgcccuggc ccugacccag accugggcca ugccccugcc cccccacccc ggccaccccg      180

gcuacaucaa cuucagcuac gaggugcuga ccccccugaa gugguaccag agcaugauca      240

gaccccccua cagcagcuac ggcuacgagc ccaugggcgg cuggugagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6616
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt4)

<400>  6616
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cccccagaac ccuggugcug cugcugagcg      120

gcgcccuggc ccugacccag accugggcca ugccccugcc cccccacccc ggccaccccg      180

gcuacaucaa cuucagcuac gaggugcuga ccccccugaa gugguaccag agcaugauca      240

gacccccccc cauccugccc gaccugcacc uggaggccug gcccgccacc gacaagacca      300

agcaggagga gguggacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6617
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt4)

<400>  6617
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccugcug ggcgccgccu      120

ucagcaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccuacacc agcuacggcu      240

acgagcccau gggcggcugg cugcaccacc agaucauccc cguggugagc cagcagaccc      300

cccagagcca cgcccugcag ccccaccacc acauccccau ggugcccgcc cagcagcccg      360

gcauccccca gcagcccaug augccccugc ccggccagca cagcaugacc cccacccagc      420

accaccagcc caaccugccc cugcccgccc agcagcccuu ccagccccag cccgugcagc      480

cccagcccca ccagccccug cagccccaga gccccaugca ccccauccag ccccugcugc      540

cccagccccc ccugcccccc auguucagca ugcagagccu gcugcccgac cugccccugg      600

aggccuggcc cgccaccgac aagaccaaga gagaggaggu ggacugagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6618
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt4)

<400>  6618
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagaa caugaucaga caccccuaca      180

ccagcuacgg cuacgagccc augggcggcu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6619
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt4)

<400>  6619
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagaa caugaucaga caccccagcc      180

ugcugcccga ccugccccug gaggccuggc ccgccaccga caagaccaag agagaggagg      240

uggacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6620
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt4)

<400>  6620
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cccccagaac ccuggugcug cugcugagcg      120

gcgcccuggc ccugacccag accugggcca ugccccugcc cccccacccc ggccaccccg      180

gcuacaucaa cuucagcuac gaggugcuga ccccccugaa gugguaccag aacaugauca      240

gacaccccua caccagcuac ggcuacgagc ccaugggcgg cuggugagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6621
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt4)

<400>  6621
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cccccagaac ccuggugcug cugcugagcg      120

gcgcccuggc ccugacccag accugggcca ugccccugcc cccccacccc ggccaccccg      180

gcuacaucaa cuucagcuac gaggugcuga ccccccugaa gugguaccag aacaugauca      240

gacaccccag ccugcugccc gaccugcccc uggaggccug gcccgccacc gacaagacca      300

agagagagga gguggacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6622
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt4)

<400>  6622
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccugcug ggcgccgccu      120

ucagcaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacauca      180

gacaccccua caccagcuac ggcuacgagc ccaugggcgg cuggcugcac caccagauca      240

uccccguggu gagccagcag accccccaga gccacgcccu gcagccccac caccacaucc      300

ccauggugcc cgcccagcag cccggcaucc cccagcagcc caugaugccc cugcccggcc      360

agcacagcau gacccccacc cagcaccacc agcccaaccu gccccugccc gcccagcagc      420

ccuuccagcc ccagcccgug cagccccagc cccaccagcc ccugcagccc cagagcccca      480

ugcaccccau ccagccccug cugccccagc ccccccugcc ccccauguuc agcaugcaga      540

gccugcugcc cgaccugccc cuggaggccu ggcccgccac cgacaagacc aagagagagg      600

agguggacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  6623
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt4)

<400>  6623
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuucgc cugccugcug ggcgccagcc      120

uggccaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccuacacc agcuacggcu      240

acgagcccau gggcggcugg cugcaccacc agaucauccc cguggugagc cagcagaccc      300

cccagagcca cgcccugcag ccccaccacc acauccccau ggugcccgcc cagcagcccg      360

gcauccccca gcagcccaug augccccugc ccggccagca cagcaugacc cccacccagc      420

accaccagcc caaccugccc cugcccgccc agcagcccuu ccagccccag cccgugcagc      480

cccagcccca ccagccccug cagccccaga gccccaugca ccccauccag ccccugcugc      540

cccagccccc ccugcccccc auguucagca ugcagagccu gcugcccgac cugccccugg      600

aggccuggcc cgccaccgac aagaccaaga gagaggaggu ggacugagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6624
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt4)

<400>  6624
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccugcug ggcgccgccu      120

ucagcaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccagccug cugcccgacc      240

ugccccugga ggccuggccc gccaccgaca agaccaagag agaggaggug gacugaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  6625
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt4)

<400>  6625
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccugcug ggcgccgccu      120

ucagcaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

accuguaccu ggaggccauc agaaucgaca gaaccgccuu cgugcugacc ccccugaagu      240

gguaccagaa caugaucaga caccccuaca ccagcuacgg cuacgagccc augggcggcu      300

ggcugcacca ccagaucauc cccgugguga gccagcagac cccccagagc cacgcccugc      360

agccccacca ccacaucccc auggugcccg cccagcagcc cggcaucccc cagcagccca      420

ugaugccccu gcccggccag cacagcauga cccccaccca gcaccaccag cccaaccugc      480

cccugcccgc ccagcagccc uuccagcccc agcccgugca gccccagccc caccagcccc      540

ugcagcccca gagccccaug caccccaucc agccccugcu gccccagccc ccccugcccc      600

ccauguucag caugcagagc cugcugcccg accugccccu ggaggccugg cccgccaccg      660

acaagaccaa gagagaggag guggacugag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  6626
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt4)

<400>  6626
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccugcug ggcgccgccu      120

ucagcaugcc ccugcccccc caccccggcc accccggcua caucaacuuc agcuacgagg      180

ugcugacccc ccugaagugg uaccagaaca ugaucagaca ccccaccccc cagagccacg      240

cccugcagcc ccaccaccac auccccaugg ugcccgccca gcagcccggc aucccccagc      300

agcccaugau gccccugccc ggccagcaca gcaugacccc cacccagcac caccagccca      360

accugccccu gcccgcccag cagcccuucc agccccagcc cgugcagccc cagccccacc      420

agccccugca gccccagagc cccaugcacc ccauccagcc ccugcugccc cagccccccc      480

ugccccccau guucagcaug cagagccugc ugcccgaccu gccccuggag gccuggcccg      540

ccaccgacaa gaccaagaga gaggaggugg acugaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  6627
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt4)

<400>  6627
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcccc cccaccccgg ccaccccggc uacaucaacu      120

ucagcuacga ggugcugacc ccccugaagu gguaccagaa caugaucaga caccccuaca      180

ccagcuacgg cuacgagccc augggcggcu ggcugcacca ccagaucauc cccgugguga      240

gccagcagac cccccagagc cacgcccugc agccccacca ccacaucccc auggugcccg      300

cccagcagcc cggcaucccc cagcagccca ugaugccccu gcccggccag cacagcauga      360

cccccaccca gcaccaccag cccaaccugc cccugcccgc ccagcagccc uuccagcccc      420

agcccgugca gccccagccc caccagcccc ugcagcccca gagccccaug caccccaucc      480

agccccugcu gccccagccc ccccugcccc ccauguucag caugcagagc cugcugcccg      540

accugccccu ggaggccugg cccgccaccg acaagaccaa gagagaggag guggacugag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  6628
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt4)

<400>  6628
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg ccagacugcc ccugcugcug ggccugcugc      120

ugcugcccag acccggcaga ccccuggacc uggccgacua caccuacgac cuggccgagg      180

aggacgacag cgagccccug aacuacaagg accccugcaa ggccgccgcc uuccugggcg      240

acaucgcccu ggacgaggag gaccugagag ccuuccaggu gcagcaggcc guggaccuga      300

gaagacacac cgccagaaag agcagcauca aggccgccgu gcccggcaac accagcaccc      360

ccagcugcca gagcaccaac ggccagcccc agagaggcgc cugcggcaga uggagaggca      420

gaagcagaag cagaagagcc gccaccagca gacccgagag aguguggccc gacggcguga      480

uccccuucgu gaucggcggc aacuucaccg gcagccagag agccguguuc agacaggcca      540

ugagacacug ggagaagcac accugcguga ccuuccugga gagaaccgac gaggacagcu      600

acaucguguu caccuacaga cccugcggcu gcugcagcua cgugggcaga agaggcggcg      660

gcccccaggc caucagcauc ggcaagaacu gcgacaaguu cggcaucgug gugcacgagc      720

ugggccacgu ggugggcuuc uggcacgagc acaccagacc cgacagagac agacacguga      780

gcaucgugag agagaacauc cagcccggcc aggaguacaa cuuccugaag auggagcccc      840

aggaggugga gagccugggc gagaccuacg acuucgacag caucaugcac uacgccagaa      900

acaccuucag cagaggcauc uuccuggaca ccaucgugcc caaguacgag gugaacggcg      960

ugaagccccc caucggccag agaaccagac ugagcaaggg cgacaucgcc caggccagaa     1020

agcuguacaa gugccccgcc ugcggcgaga cccugcagga cagcaccggc aacuucagca     1080

gccccgagua ccccaacggc uacagcgccc acaugcacug cguguggaga aucagcguga     1140

cccccggcga gaagaucauc cugaacuuca ccagccugga ccuguacaga agcagacugu     1200

gcugguacga cuacguggag gugagagacg gcuucuggag aaaggccccc cugagaggca     1260

gauucugcgg cagcaagcug cccgagccca ucgugagcac cgacagcaga cugugggugg     1320

aguucagaag cagcagcaac ugggugggca agggcuucuu cgccguguac gaggccaucu     1380

gcggcggcga cgugaagaag gacuacggcc acauccagag ccccaacuac cccgacgacu     1440

acagacccag caaggugugc aucuggagaa uccaggugag cgagggcuuc cacgugggcc     1500

ugaccuucca gagcuucgag aucgagagac acgacagcug cgccuacgac uaccuggagg     1560

ugagagacgg ccacagcgag agcagcaccc ugaucggcag auacugcggc uacgagaagc     1620

ccgacgacau caagagcacc agcagcagac uguggcugaa guucgugagc gacggcagca     1680

ucaacaaggc cggcuucgcc gugaacuucu ucaaggaggu ggacgagugc agcagaccca     1740

acagaggcgg cugcgagcag agaugccuga acacccuggg cagcuacaag ugcagcugcg     1800

accccggcua cgagcuggcc cccgacaaga gaagaugcga ggccgccugc ggcggcuucc     1860

ugaccaagcu gaacggcagc aucaccagcc ccggcuggcc caaggaguac ccccccaaca     1920

agaacugcau cuggcagcug guggccccca cccaguacag aaucagccug caguucgacu     1980

ucuucgagac cgagggcaac gacgugugca aguacgacuu cguggaggug agaagcggcc     2040

ugaccgccga cagcaagcug cacggcaagu ucugcggcag cgagaagccc gaggugauca     2100

ccagccagua caacaacaug agaguggagu ucaagagcga caacaccgug agcaagaagg     2160

gcuucaaggc ccacuucuuc agcgacaagg acgagugcag caaggacaac ggcggcugcc     2220

agcaggacug cgugaacacc uucggcagcu acgagugcca gugcagaagc ggcuucgugc     2280

ugcacgacaa caagcacgac ugcaaggagg ccggcugcga ccacaaggug accagcacca     2340

gcggcaccau caccagcccc aacuggcccg acaaguaccc cagcaagaag gagugcaccu     2400

gggccaucag cagcaccccc ggccacagag ugaagcugac cuucauggag auggacaucg     2460

agagccagcc cgagugcgcc uacgaccacc uggagguguu cgacggcaga gacgccaagg     2520

cccccgugcu gggcagauuc ugcggcagca agaagcccga gcccgugcug gccaccggca     2580

gcagaauguu ccugagauuc uacagcgaca acagcgugca gagaaagggc uuccaggcca     2640

gccacgccac cgagugcggc ggccagguga gagccgacgu gaagaccaag gaccuguaca     2700

gccacgccca guucggcgac aacaacuacc ccggcggcgu ggacugcgag ugggugaucg     2760

uggccgagga gggcuacggc guggagcugg uguuccagac cuucgaggug gaggaggaga     2820

ccgacugcgg cuacgacuac auggagcugu ucgacggcua cgacagcacc gcccccagac     2880

ugggcagaua cugcggcagc ggcccccccg aggaggugua cagcgccggc gacagcgugc     2940

uggugaaguu ccacagcgac gacaccauca ccaagaaggg cuuccaccug agauacacca     3000

gcaccaaguu ccaggacacc cugcacagca gaaagugagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  6629
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt4)

<400>  6629
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggca ccagaugccu gcuggcccug cugcugcccc      120

aggugcugcu gggcggcgcc gccggccugg ugcccgagcu gggcagaaga aaguucgccg      180

ccgccagcag cggcagaccc agcagccagc ccagcgacga ggugcugagc gaguucgagc      240

ugagacugcu gagcauguuc ggccugaagc agagacccac ccccagcaga gacgccgugg      300

ugccccccua caugcuggac cuguacagaa gacacagcgg ccagcccggc agccccgccc      360

ccgaccacag acuggagaga gccgccagca gagccaacac cgugagaagc uuccaccacg      420

aggagagccu ggaggagcug cccgagacca gcggcaagac caccagaaga uucuucuuca      480

accugagcag cauccccacc gaggaguuca ucaccagcgc cgagcugcag guguucagag      540

agcagaugca ggacgcccug ggcaacaaca gcagcuucca ccacagaauc aacaucuacg      600

agaucaucaa gcccgccacc gccaacagca aguuccccgu gaccagacug cuggacacca      660

gacuggugaa ccagaacgcc agcagauggg agagcuucga cgugaccccc gccgugauga      720

gauggaccgc ccagggccac gccaaccacg gcuucguggu ggagguggcc caccuggagg      780

agaagcaggg cgugagcaag agacacguga gaaucagcag aagccugcac caggacgagc      840

acagcuggag ccagaucaga ccccugcugg ugaccuucgg ccacgacggc aagggccacc      900

cccugcacaa gagagagaag agacaggcca agcacaagca gagaaagaga cugaagagca      960

gcugcaagag acacccccug uacguggacu ucagcgacgu gggcuggaac gacuggaucg     1020

uggccccccc cggcuaccac gccuucuacu gccacggcga gugccccuuc ccccuggccg     1080

accaccugaa cagcaccaac cacgccaucg ugcagacccu ggugaacagc gugaacagca     1140

agauccccaa ggccugcugc gugcccaccg agcugagcgc caucagcaug cuguaccugg     1200

acgagaacga gaagguggug cugaagaacu accaggacau ggugguggag ggcugcggcu     1260

gcagaugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  6630
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt4)

<400>  6630
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auccccggca acagaaugcu gaugguggug cugcugugcc      120

aggugcugcu gggcggcgcc agccacgcca gccugauccc cgagaccggc aagaagaagg      180

uggccgagau ccagggccac gccggcggca gaagaagcgg ccagagccac gagcugcuga      240

gagacuucga ggccacccug cugcagaugu ucggccugag aagaagaccc cagcccagca      300

agagcgccgu gauccccgac uacaugagag accuguacag acugcagagc ggcgaggagg      360

aggaggagca gauccacagc accggccugg aguaccccga gagacccgcc agcagagcca      420

acaccgugag aagcuuccac cacgaggagc accuggagaa cauccccggc accagcgaga      480

acagcgccuu cagauuccug uucaaccuga gcagcauccc cgagaacgag gugaucagca      540

gcgccgagcu gagacuguuc agagagcagg uggaccaggg ccccgacugg gagagaggcu      600

uccacagaau caacaucuac gaggugauga agccccccgc cgagguggug cccggccacc      660

ugaucaccag acugcuggac accagacugg ugcaccacaa cgugaccaga ugggagaccu      720

ucgacgugag ccccgccgug cugagaugga ccagagagaa gcagcccaac uacggccugg      780

ccaucgaggu gacccaccug caccagacca gaacccacca gggccagcac gugagaauca      840

gcagaagccu gccccagggc agcggcaacu gggcccagcu gagaccccug cuggugaccu      900

ucggccacga cggcagaggc cacgcccuga ccagaagaag aagagccaag agaagcccca      960

agcaccacag ccagagagcc agaaagaaga acaagaacug cagaagacac agccuguacg     1020

uggacuucag cgacgugggc uggaacgacu ggaucguggc cccccccggc uaccaggccu     1080

ucuacugcca cggcgacugc cccuuccccc uggccgacca ccugaacagc accaaccacg     1140

ccaucgugca gacccuggug aacagcguga acagcagcau ccccaaggcc ugcugcgugc     1200

ccaccgagcu gagcgccauc agcaugcugu accuggacga guacgacaag guggugcuga     1260

agaacuacca ggagauggug guggagggcu gcggcugcag augaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  6631
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt4)

<400>  6631
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggccugg gcagaagagc ccaguggcug ugcugguggu      120

ggggccugcu gugcagcugc ugcggccccc ccccccugag acccccccug cccgccgccg      180

ccgccgccgc cgccggcggc cagcugcugg gcgacggcgg cagccccggc agaaccgagc      240

agcccccccc cagcccccag agcagcagcg gcuuccugua cagaagacug aagacccagg      300

agaagagaga gaugcagaag gagauccuga gcgugcuggg ccugccccac agacccagac      360

cccugcacgg ccugcagcag ccccagcccc ccgcccugag acagcaggag gagcagcagc      420

agcagcagca gcugcccaga ggcgagcccc cccccggcag acugaagagc gccccccugu      480

ucaugcugga ccuguacaac gcccugagcg ccgacaacga cgaggacggc gccagcgagg      540

gcgagagaca gcagagcugg ccccacgagg ccgccagcag cagccagaga agacagcccc      600

cccccggcgc cgcccacccc cugaacagaa agagccugcu ggcccccggc agcggcagcg      660

gcggcgccag cccccugacc agcgcccagg acagcgccuu ccugaacgac gccgacaugg      720

ugaugagcuu cgugaaccug guggaguacg acaaggaguu cagccccaga cagagacacc      780

acaaggaguu caaguucaac cugagccaga uccccgaggg cgagguggug accgccgccg      840

aguucagaau cuacaaggac ugcgugaugg gcagcuucaa gaaccagacc uuccugauca      900

gcaucuacca ggugcugcag gagcaccagc acagagacag cgaccuguuc cugcuggaca      960

ccagaguggu gugggccagc gaggagggcu ggcuggaguu cgacaucacc gccaccagca     1020

accugugggu ggugaccccc cagcacaaca ugggccugca gcugagcgug gugaccagag     1080

acggcgugca cgugcacccc agagccgccg gccugguggg cagagacggc cccuacgaca     1140

agcagcccuu caugguggcc uucuucaagg ugagcgaggu gcacgugaga accaccagaa     1200

gcgccagcag cagaagaaga cagcagagca gaaacagaag cacccagagc caggacgugg     1260

ccagagugag cagcgccagc gacuacaaca gcagcgagcu gaagaccgcc ugcagaaagc     1320

acgagcugua cgugagcuuc caggaccugg gcuggcagga cuggaucauc gcccccaagg     1380

gcuacgccgc caacuacugc gacggcgagu gcagcuuccc ccugaacgcc cacaugaacg     1440

ccaccaacca cgccaucgug cagacccugg ugcaccugau gaaccccgag uacgugccca     1500

agcccugcug cgcccccacc aagcugaacg ccaucagcgu gcuguacuuc gacgacaaca     1560

gcaacgugau ccugaagaag uacagaaaca ugguggugag agccugcggc ugccacugag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  6632
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt4)

<400>  6632
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugagaa gccugagagc cgccgccccc cacagcuucg      120

uggcccugug ggccccccug uuccugcuga gaagcgcccu ggccgacuuc agccuggaca      180

acgaggugca cagcagcuuc auccacagaa gacugagaag ccaggagaga agagagaugc      240

agagagagau ccugagcauc cugggccugc cccacagacc cagaccccac cugcagggca      300

agcacaacag cgcccccaug uucaugcugg accuguacaa cgccauggcc guggaggagg      360

gcggcggccc cggcggccag ggcuucagcu accccuacaa ggccguguuc agcacccagg      420

gccccccccu ggccagccug caggacagcc acuuccugac cgacgccgac auggugauga      480

gcuucgugaa ccugguggag cacgacaagg aguucuucca ccccagauac caccacagag      540

aguucagauu cgaccugagc aagauccccg agggcgaggc cgugaccgcc gccgaguuca      600

gaaucuacaa ggacuacauc agagagagau ucgacaacga gaccuucaga aucagcgugu      660

accaggugcu gcaggagcac cugggcagag agagcgaccu guuccugcug gacagcagaa      720

cccugugggc cagcgaggag ggcuggcugg uguucgacau caccgccacc agcaaccacu      780

ggguggugaa ccccagacac aaccugggcc ugcagcugag cguggagacc cuggacggcc      840

agagcaucaa ccccaagcug gccggccuga ucggcagaca cggcccccag aacaagcagc      900

ccuucauggu ggccuucuuc aaggccaccg aggugcacuu cagaagcauc agaagcaccg      960

gcagcaagca gagaagccag aacagaagca agacccccaa gaaccaggag gcccugagaa     1020

uggccaacgu ggccgagaac agcagcagcg accagagaca ggccugcaag aagcacgagc     1080

uguacgugag cuucagagac cugggcuggc aggacuggau caucgccccc gagggcuacg     1140

ccgccuacua cugcgagggc gagugcgccu ucccccugaa cagcuacaug aacgccacca     1200

accacgccau cgugcagacc cuggugcacu ucaucaaccc cgagaccgug cccaagcccu     1260

gcugcgcccc cacccagcug aacgccauca gcgugcugua cuucgacgac agcagcaacg     1320

ugauccugaa gaaguacaga aacauggugg ugagagccug cggcugccac ugaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  6633
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt4)

<400>  6633
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggccagcg ccgcccugcu gugccugcug cugaccgccg      120

ccgccuucag cccccagggc cuggcccagc ccgugggcau caacaccagc accaccugcu      180

gcuacagauu caucaacaag aagaucccca agcagagacu ggagagcuac agaagaacca      240

ccagcagcca cugccccaga gaggccguga ucuucaagac caagcuggac aaggagaucu      300

gcgccgaccc cacccagaag ugggugcagg acuucaugaa gcaccuggac aagaagaccc      360

agacccccaa gcugugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  6634
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt4)

<400>  6634
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcugaccc ugaucauccu gcugcccgug gugagcaagu      120

ucagcuucgu gagccugagc gccccccagc acuggagcug ccccgagggc acccuggccg      180

gcaacggcaa cagcaccugc gugggccccg cccccuuccu gaucuucagc cacggcaaca      240

gcaucuucag aaucgacacc gagggcacca acuacgagca gcugguggug gacgccggcg      300

ugagcgugau cauggacuuc cacuacaacg agaagagaau cuacugggug gaccuggaga      360

gacagcugcu gcagagagug uuccugaacg gcagcagaca ggagagagug ugcaacaucg      420

agaagaacgu gagcggcaug gccaucaacu ggaucaacga ggaggugauc uggagcaacc      480

agcaggaggg caucaucacc gugaccgaca ugaagggcaa caacagccac auccugcuga      540

gcgcccugaa guaccccgcc aacguggccg uggaccccgu ggagagauuc aucuucugga      600

gcagcgaggu ggccggcagc cuguacagag ccgaccugga cggcgugggc gugaaggccc      660

ugcuggagac cagcgagaag aucaccgccg ugagccugga cgugcuggac aagagacugu      720

ucuggaucca guacaacaga gagggcagca acagccugau cugcagcugc gacuacgacg      780

gcggcagcgu gcacaucagc aagcacccca cccagcacaa ccuguucgcc augagccugu      840

ucggcgacag aaucuucuac agcaccugga agaugaagac caucuggauc gccaacaagc      900

acaccggcaa ggacauggug agaaucaacc ugcacagcag cuucgugccc cugggcgagc      960

ugaagguggu gcacccccug gcccagccca aggccgagga cgacaccugg gagcccgagc     1020

agaagcugug caagcugaga aagggcaacu gcagcagcac cgugugcggc caggaccugc     1080

agagccaccu gugcaugugc gccgagggcu acgcccugag cagagacaga aaguacugcg     1140

aggacgugaa cgagugcgcc uucuggaacc acggcugcac ccugggcugc aagaacaccc     1200

ccggcagcua cuacugcacc ugccccgugg gcuucgugcu gcugcccgac ggcaagagau     1260

gccaccagcu ggugagcugc cccagaaacg ugagcgagug cagccacgac ugcgugcuga     1320

ccagcgaggg cccccugugc uucugccccg agggcagcgu gcuggagaga gacggcaaga     1380

ccugcagcgg cugcagcagc cccgacaacg gcggcugcag ccagcugugc gugccccuga     1440

gccccgugag cugggagugc gacugcuucc ccggcuacga ccugcagcug gacgagaaga     1500

gcugcgccgc cagcggcccc cagcccuucc ugcuguucgc caacagccag gacaucagac     1560

acaugcacuu cgacggcacc gacuacggca cccugcugag ccagcagaug ggcauggugu     1620

acgcccugga ccacgacccc guggagaaca agaucuacuu cgcccacacc gcccugaagu     1680

ggaucgagag agccaacaug gacggcagcc agagagagag acugaucgag gagggcgugg     1740

acgugcccga gggccuggcc guggacugga ucggcagaag auucuacugg accgacagag     1800

gcaagagccu gaucggcaga agcgaccuga acggcaagag aagcaagauc aucaccaagg     1860

agaacaucag ccagcccaga ggcaucgccg ugcaccccau ggccaagaga cuguucugga     1920

ccgacaccgg caucaacccc agaaucgaga gcagcagccu gcagggccug ggcagacugg     1980

ugaucgccag cagcgaccug aucuggccca gcggcaucac caucgacuuc cugaccgaca     2040

agcuguacug gugcgacgcc aagcagagcg ugaucgagau ggccaaccug gacggcagca     2100

agagaagaag acugacccag aacgacgugg gccaccccuu cgccguggcc guguucgagg     2160

acuacgugug guucagcgac ugggccaugc ccagcgugau gagagugaac aagagaaccg     2220

gcaaggacag agugagacug cagggcagca ugcugaagcc cagcagccug gugguggugc     2280

acccccuggc caagcccggc gccgaccccu gccuguacca gaacggcggc ugcgagcaca     2340

ucugcaagaa gagacugggc accgccuggu gcagcugcag agagggcuuc augaaggcca     2400

gcgacggcaa gaccugccug gcccuggacg gccaccagcu gcuggccggc ggcgaggugg     2460

accugaagaa ccaggugacc ccccuggaca uccugagcaa gaccagagug agcgaggaca     2520

acaucaccga gagccagcac augcuggugg ccgagaucau ggugagcgac caggacgacu     2580

gcgcccccgu gggcugcagc auguacgcca gaugcaucag cgagggcgag gacgccaccu     2640

gccagugccu gaagggcuuc gccggcgacg gcaagcugug cagcgacauc gacgagugcg     2700

agaugggcgu gcccgugugc ccccccgcca gcagcaagug caucaacacc gagggcggcu     2760

acgugugcag augcagcgag ggcuaccagg gcgacggcau ccacugccug gacaucgacg     2820

agugccagcu gggcgagcac agcugcggcg agaacgccag cugcaccaac accgagggcg     2880

gcuacaccug caugugcgcc ggcagacuga gcgagcccgg ccugaucugc cccgacagca     2940

cccccccccc ccaccugaga gaggacgacc accacuacag cgugagaaac agcgacagcg     3000

agugcccccu gagccacgac ggcuacugcc ugcacgacgg cgugugcaug uacaucgagg     3060

cccuggacaa guacgccugc aacugcgugg ugggcuacau cggcgagaga ugccaguaca     3120

gagaccugaa guggugggag cugagacacg ccggccacgg ccagcagcag aaggugaucg     3180

ugguggccgu gugcguggug gugcugguga ugcugcugcu gcugagccug uggggcgccc     3240

acuacuacag aacccagaag cugcugagca agaaccccaa gaaccccuac gaggagagca     3300

gcagagacgu gagaagcaga agacccgccg acaccgagga cggcaugagc agcugccccc     3360

agcccugguu cguggugauc aaggagcacc aggaccugaa gaacggcggc cagcccgugg     3420

ccggcgagga cggccaggcc gccgacggca gcaugcagcc caccagcugg agacaggagc     3480

cccagcugug cggcaugggc accgagcagg gcugcuggau ccccgugagc agcgacaagg     3540

gcagcugccc ccaggugaug gagagaagcu uccacaugcc cagcuacggc acccagaccc     3600

uggagggcgg cguggagaag ccccacagcc ugcugagcgc caacccccug uggcagcaga     3660

gagcccugga ccccccccac cagauggagc ugacccagug aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  6635
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt4)

<400>  6635
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggca gaagaaugga gaugcugugc gccggcagag      120

ugcccgcccu gcugcugugc cugggcuucc accugcugca ggccgugcug agcaccaccg      180

ugauccccag cugcaucccc ggcgagagca gcgacaacug caccgcccug gugcagaccg      240

aggacaaccc cagaguggcc caggugagca ucaccaagug cagcagcgac augaacggcu      300

acugccugca cggccagugc aucuaccugg uggacaugag ccagaacuac ugcagaugcg      360

aggugggcua caccggcgug agaugcgagc acuucuuccu gaccgugcac cagccccuga      420

gcaaggagua cguggcccug accgugaucc ugaucauccu guuccugauc accguggugg      480

gcagcaccua cuacuucugc agaugguaca gaaacagaaa gagcaaggag cccaagaagg      540

aguacgagag agugaccagc ggcgaccccg agcugcccca ggugugagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  6636
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt4)

<400>  6636
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgagggcg agaucaccac cuucaccgcc cugaccgaga      120

aguucaaccu gccccccggc aacuacaaga agcccaagcu gcuguacugc agcaacggcg      180

gccacuuccu gagaauccug cccgacggca ccguggacgg caccagagac agaagcgacc      240

agcacaucca gcugcagcug agcgccgaga gcgugggcga gguguacauc aagagcaccg      300

agaccggcca guaccuggcc auggacaccg acggccugcu guacggcagc cagaccccca      360

acgaggagug ccuguuccug gagagacugg aggagaacca cuacaacacc uacaucagca      420

agaagcacgc cgagaagaac ugguucgugg gccugaagaa gaacggcagc ugcaagagag      480

gccccagaac ccacuacggc cagaaggcca uccuguuccu gccccugccc gugagcagcg      540

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  6637
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt4)

<400>  6637
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggcgugg gcggcggcga cguggaggac gugaccccca      120

gacccggcgg cugccagauc agcggcagag gcgccagagg cugcaacggc auccccggcg      180

ccgccgccug ggaggccgcc cugcccagaa gaagacccag aagacacccc agcgugaacc      240

ccagaagcag agccgccggc agccccagaa ccagaggcag aagaaccgag gagagaccca      300

gcggcagcag acugggcgac agaggcagag gcagagcccu gcccggcggc agacugggcg      360

gcagaggcag aggcagagcc cccgagagag ugggcggcag aggcagaggc agaggcaccg      420

ccgcccccag agccgccccc gccgccagag gcagcagacc cggccccgcc ggcaccaugg      480

ccgccggcag caucaccacc cugcccgccc ugcccgagga cggcggcagc ggcgccuucc      540

cccccggcca cuucaaggac cccaagagac uguacugcaa gaacggcggc uucuuccuga      600

gaauccaccc cgacggcaga guggacggcg ugagagagaa gagcgacccc cacaucaagc      660

ugcagcugca ggccgaggag agaggcgugg ugagcaucaa gggcgugugc gccaacagau      720

accuggccau gaaggaggac ggcagacugc uggccagcaa gugcgugacc gacgagugcu      780

ucuucuucga gagacuggag agcaacaacu acaacaccua cagaagcaga aaguacacca      840

gcugguacgu ggcccugaag agaaccggcc aguacaagcu gggcagcaag accggccccg      900

gccagaaggc cauccuguuc cugcccauga gcgccaagag cugaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  6638
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt4)

<400>  6638
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uccugaccug gauccugccc acccugcugu      120

acagaagcug cuuccacauc aucugccugg ugggcaccau cagccuggcc ugcaacgaca      180

ugacccccga gcagauggcc accaacguga acugcagcag ccccgagaga cacaccagaa      240

gcuacgacua cauggagggc ggcgacauca gagugagaag acuguucugc agaacccagu      300

gguaccugag aaucgacaag agaggcaagg ugaagggcac ccaggagaug aagaacaacu      360

acaacaucau ggagaucaga accguggccg ugggcaucgu ggccaucaag ggcguggaga      420

gcgaguucua ccuggccaug aacaaggagg gcaagcugua cgccaagaag gagugcaacg      480

aggacugcaa cuucaaggag cugauccugg agaaccacua caacaccuac gccagcgcca      540

aguggaccca caacggcggc gagauguucg uggcccugaa ccagaagggc auccccguga      600

gaggcaagaa gaccaagaag gagcagaaga ccgcccacuu ccugcccaug gccaucaccu      660

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  6639
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt4)

<400>  6639
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugcugc ccagcguggu gcugaagcug uuccuggccg      120

ccgugcugag cgcccuggug accggcgaga gccuggagag acugagaaga ggccuggccg      180

ccggcaccag caaccccgac ccccccaccg ugagcaccga ccagcugcug ccccugggcg      240

gcggcagaga cagaaaggug agagaccugc aggaggccga ccuggaccug cugagaguga      300

cccugagcag caagccccag gcccuggcca cccccaacaa ggaggagcac ggcaagagaa      360

agaagaaggg caagggccug ggcaagaaga gagaccccug ccugagaaag uacaaggacu      420

ucugcaucca cggcgagugc aaguacguga aggagcugag agcccccagc ugcaucugcc      480

accccggcua ccacggcgag agaugccacg gccugagccu gcccguggag aacagacugu      540

acaccuacga ccacaccacc auccuggccg ugguggccgu ggugcugagc agcgugugcc      600

ugcuggugau cgugggccug cugauguuca gauaccacag aagaggcggc uacgacgugg      660

agaacgagga gaaggugaag cugggcauga ccaacagcca cugaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  6640
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt4)

<400>  6640
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcugcc cgcccugcug cugcagcacg      120

ugcugcugca ccugcugcug cugcccaucg ccauccccua cgccgagggc cagagaaaga      180

gaagaaacac cauccacgag uucaagaaga gcgccaagac cacccugauc aagaucgacc      240

ccgcccugaa gaucaagacc aagaagguga acaccgccga ccagugcgcc aacagaugca      300

ccagaaacaa gggccugccc uucaccugca aggccuucgu guucgacaag gccagaaagc      360

agugccugug guuccccuuc aacagcauga gcagcggcgu gaagaaggag uucggccacg      420

aguucgaccu guacgagaac aaggacuaca ucagaaacug caucaucggc aagggcagaa      480

gcuacaaggg caccgugagc aucaccaaga gcggcaucaa gugccagccc uggagcagca      540

ugauccccca cgagcacagc uuccugccca gcagcuacag aggcaaggac cugcaggaga      600

acuacugcag aaaccccaga ggcgaggagg gcggccccug gugcuucacc agcaaccccg      660

aggugagaua cgaggugugc gacauccccc agugcagcga gguggagugc augaccugca      720

acggcgagag cuacagaggc cugauggacc acaccgagag cggcaagauc ugccagagau      780

gggaccacca gaccccccac agacacaagu uccugcccga gagauacccc gacaagggcu      840

ucgacgacaa cuacugcaga aaccccgacg gccagcccag acccuggugc uacacccugg      900

acccccacac cagaugggag uacugcgcca ucaagaccug cgccgacaac accaugaacg      960

acaccgacgu gccccuggag accaccgagu gcauccaggg ccagggcgag ggcuacagag     1020

gcaccgugaa caccaucugg aacggcaucc ccugccagag augggacagc caguaccccc     1080

acgagcacga caugaccccc gagaacuuca agugcaagga ccugagagag aacuacugca     1140

gaaaccccga cggcagcgag agccccuggu gcuucaccac cgaccccaac aucagagugg     1200

gcuacugcag ccagaucccc aacugcgaca ugagccacgg ccaggacugc uacagaggca     1260

acggcaagaa cuacaugggc aaccugagcc agaccagaag cggccugacc ugcagcaugu     1320

gggacaagaa cauggaggac cugcacagac acaucuucug ggagcccgac gccagcaagc     1380

ugaacgagaa cuacugcaga aaccccgacg acgacgccca cggccccugg ugcuacaccg     1440

gcaacccccu gauccccugg gacuacugcc ccaucagcag augcgagggc gacaccaccc     1500

ccaccaucgu gaaccuggac caccccguga ucagcugcgc caagaccaag cagcugagag     1560

uggugaacgg cauccccacc agaaccaaca ucggcuggau ggugagccug agauacagaa     1620

acaagcacau cugcggcggc agccugauca aggagagcug ggugcugacc gccagacagu     1680

gcuuccccag cagagaccug aaggacuacg aggccuggcu gggcauccac gacgugcacg     1740

gcagaggcga cgagaagugc aagcaggugc ugaacgugag ccagcuggug uacggccccg     1800

agggcagcga ccuggugcug augaagcugg ccagacccgc cgugcuggac gacuucguga     1860

gcaccaucga ccugcccaac uacggcugca ccauccccga gaagaccagc ugcagcgugu     1920

acggcugggg cuacaccggc cugaucaacu acgacggccu gcugagagug gcccaccugu     1980

acaucauggg caacgagaag ugcagccagc accacagagg caaggugacc cugaacgaga     2040

gcgagaucug cgccggcgcc gagaagaucg gcagcggccc cugcgagggc gacuacggcg     2100

gcccccuggu gugcgagcag cacaagauga gaauggugcu gggcgugauc gugcccggca     2160

gaggcugcgc cauccccaac agacccggca ucuucgugag aguggccuac uacgccaagu     2220

ggauccacaa gaucauccug accuacaagg ugccccagag cugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  6641
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt4)

<400>  6641
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggccg ccgccaucgg caucgaccug ggcaccaccu      120

acagcugcgu gggcguguuc cagcacggca agguggagau caucgccaac gaccagggca      180

acagaaccac ccccagcuac guggccuuca ccgacaccga gagacugauc ggcgacgccg      240

ccaagaacca gguggcccug aacccccaga acaccguguu cgacgccaag agacugaucg      300

gcagaaaguu cggcgacccc guggugcaga gcgacaugaa gcacuggccc uuccagguga      360

ucaacgacgg cgacaagccc aaggugcagg ugagcuacaa gggcgagacc aaggccuucu      420

accccgagga gaucagcagc auggugcuga ccaagaugaa ggagaucgcc gaggccuacc      480

ugggcuaccc cgugaccaac gccgugauca ccgugcccgc cuacuucaac gacagccaga      540

gacaggccac caaggacgcc ggcgugaucg ccggccugaa cgugcugaga aucaucaacg      600

agcccaccgc cgccgccauc gccuacggcc uggacagaac cggcaagggc gagagaaacg      660

ugcugaucuu cgaccugggc ggcggcaccu ucgacgugag cauccugacc aucgacgacg      720

gcaucuucga ggugaaggcc accgccggcg acacccaccu gggcggcgag gacuucgaca      780

acagacuggu gaaccacuuc guggaggagu ucaagagaaa gcacaagaag gacaucagcc      840

agaacaagag agccgugaga agacugagaa ccgccugcga gagagccaag agaacccuga      900

gcagcagcac ccaggccagc cuggagaucg acagccuguu cgagggcauc gacuucuaca      960

ccagcaucac cagagccaga uucgaggagc ugugcagcga ccuguucaga agcacccugg     1020

agcccgugga gaaggcccug agagacgcca agcuggacaa ggcccagauc cacgaccugg     1080

ugcugguggg cggcagcacc agaaucccca aggugcagaa gcugcugcag gacuucuuca     1140

acggcagaga ccugaacaag agcaucaacc ccgacgaggc cguggccuac ggcgccgccg     1200

ugcaggccgc cauccugaug ggcgacaaga gcgagaacgu gcaggaccug cugcugcugg     1260

acguggcccc ccugagccug ggccuggaga ccgccggcgg cgugaugacc gcccugauca     1320

agagaaacag caccaucccc accaagcaga cccagaucuu caccaccuac agcgacaacc     1380

agcccggcgu gcugauccag guguacgagg gcgagagagc caugaccaag gacaacaacc     1440

ugcugggcag auucgagcug agcggcaucc cccccgcccc cagaggcgug ccccagaucg     1500

aggugaccuu cgacaucgac gccaacggca uccugaacgu gaccgccacc gacaagagca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg cagacugagc aaggaggaga     1620

ucgagagaau ggugcaggag gccgagaagu acaaggccga ggacgaggug cagagagaga     1680

gagugagcgc caagaacgcc cuggagagcu acgccuucaa caugaagagc gccguggagg     1740

acgagggccu gaagggcaag aucagcgagg ccgacaagaa gaaggugcug gacaagugcc     1800

aggaggugau cagcuggcug gacgccaaca cccuggccga gaaggacgag uucgagcaca     1860

agagaaagga gcuggagcag gugugcaacc ccaucaucag cggccuguac cagggcgccg     1920

gcggccccgg ccccggcggc uucggcgccc agggccccaa gggcggcagc ggcagcggcc     1980

ccaccaucga ggagguggac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6642
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt4)

<400>  6642
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggccg ccgccaucgg caucgaccug ggcaccaccu      120

acagcugcgu gggcguguuc cagcacggca agguggagau caucgccaac gaccagggca      180

acagaaccac ccccagcuac guggccuuca ccgacaccga gagacugauc ggcgacgccg      240

ccaagaacca gguggcccug aacccccaga acaccguguu cgacgccaag agacugaucg      300

gcagaaaguu cggcgacccc guggugcaga gcgacaugaa gcacuggccc uuccagguga      360

ucaacgacgg cgacaagccc aaggugcagg ugagcuacaa gggcgagacc aaggccuucu      420

accccgagga gaucagcagc auggugcuga ccaagaugaa ggagaucgcc gaggccuacc      480

ugggcuaccc cgugaccaac gccgugauca ccgugcccgc cuacuucaac gacagccaga      540

gacaggccac caaggacgcc ggcgugaucg ccggccugaa cgugcugaga aucaucaacg      600

agcccaccgc cgccgccauc gccuacggcc uggacagaac cggcaagggc gagagaaacg      660

ugcugaucuu cgaccugggc ggcggcaccu ucgacgugag cauccugacc aucgacgacg      720

gcaucuucga ggugaaggcc accgccggcg acacccaccu gggcggcgag gacuucgaca      780

acagacuggu gaaccacuuc guggaggagu ucaagagaaa gcacaagaag gacaucagcc      840

agaacaagag agccgugaga agacugagaa ccgccugcga gagagccaag agaacccuga      900

gcagcagcac ccaggccagc cuggagaucg acagccuguu cgagggcauc gacuucuaca      960

ccagcaucac cagagccaga uucgaggagc ugugcagcga ccuguucaga agcacccugg     1020

agcccgugga gaaggcccug agagacgcca agcuggacaa ggcccagauc cacgaccugg     1080

ugcugguggg cggcagcacc agaaucccca aggugcagaa gcugcugcag gacuucuuca     1140

acggcagaga ccugaacaag agcaucaacc ccgacgaggc cguggccuac ggcgccgccg     1200

ugcaggccgc cauccugaug ggcgacaaga gcgagaacgu gcaggaccug cugcugcugg     1260

acguggcccc ccugagccug ggccuggaga ccgccggcgg cgugaugacc gcccugauca     1320

agagaaacag caccaucccc accaagcaga cccagaucuu caccaccuac agcgacaacc     1380

agcccggcgu gcugauccag guguacgagg gcgagagagc caugaccaag gacaacaacc     1440

ugcugggcag auucgagcug agcggcaucc cccccgcccc cagaggcgug ccccagaucg     1500

aggugaccuu cgacaucgac gccaacggca uccugaacgu gaccgccacc gacaagagca     1560

ccggcaaggc caacaagauc accaucacca acgacaaggg cagacugagc aaggaggaga     1620

ucgagagaau ggugcaggag gccgagaagu acaaggccga ggacgaggug cagagagaga     1680

gagugagcgc caagaacgcc cuggagagcu acgccuucaa caugaagagc gccguggagg     1740

acgagggccu gaagggcaag aucagcgagg ccgacaagaa gaaggugcug gacaagugcc     1800

aggaggugau cagcuggcug gacgccaaca cccuggccga gaaggacgag uucgagcaca     1860

agagaaagga gcuggagcag gugugcaacc ccaucaucag cggccuguac cagggcgccg     1920

gcggccccgg ccccggcggc uucggcgccc agggccccaa gggcggcagc ggcagcggcc     1980

ccaccaucga ggagguggac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6643
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt4)

<400>  6643
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaccgcca agggcaucgc caucggcauc gaccugggca      120

ccaccuacag cugcgugggc guguuccagc acggcaaggu ggagaucauc gccaacgacc      180

agggcaacag aaccaccccc agcuacgugg ccuucaccga caccgagaga cugaucggcg      240

acgccgccaa gaaccaggug gccaugaacc cccagaacac cguguucgac gccaagagac      300

ugaucggcag aaaguucaac gaccccgugg ugcaggccga caugaagcug uggcccuucc      360

aggugaucaa cgagggcggc aagcccaagg ugcuggugag cuacaagggc gagaacaagg      420

ccuucuaccc cgaggagauc agcagcaugg ugcugaccaa gcugaaggag accgccgagg      480

ccuuccuggg ccaccccgug accaacgccg ugaucaccgu gcccgccuac uucaacgaca      540

gccagagaca ggccaccaag gacgccggcg ugaucgccgg ccugaacgug cugagaauca      600

ucaacgagcc caccgccgcc gccaucgccu acggccugga caagggcggc cagggcgaga      660

gacacgugcu gaucuucgac cugggcggcg gcaccuucga cgugagcauc cugaccaucg      720

acgacggcau cuucgaggug aaggccaccg ccggcgacac ccaccugggc ggcgaggacu      780

ucgacaacag acuggugagc cacuucgugg aggaguucaa gagaaagcac aagaaggaca      840

ucagccagaa caagagagcc gugagaagac ugagaaccgc cugcgagaga gccaagagaa      900

cccugagcag cagcacccag gccaaccugg agaucgacag ccuguacgag ggcaucgacu      960

ucuacaccag caucaccaga gccagauucg aggagcugug cgccgaccug uucagaggca     1020

cccuggagcc cguggagaag gcccugagag acgccaagau ggacaaggcc aagauccacg     1080

acaucgugcu ggugggcggc agcaccagaa uccccaaggu gcagagacug cugcaggacu     1140

acuucaacgg cagagaccug aacaagagca ucaaccccga cgaggccgug gccuacggcg     1200

ccgccgugca ggccgccauc cugaugggcg acaagagcga gaaggugcag gaccugcugc     1260

ugcuggacgu ggccccccug agccugggcc uggagaccgc cggcggcgug augaccgccc     1320

ugaucaagag aaacagcacc auccccacca agcagaccca gaucuucacc accuacagcg     1380

acaaccagcc cggcgugcug auccaggugu acgagggcga gagagccaug accaaggaca     1440

acaaccugcu gggcagauuc gaccugaccg gcaucccccc cgcccccaga ggcgugcccc     1500

agaucgaggu gaccuucgac aucgacgcca acggcauccu gaacgugacc gccaccgaca     1560

agagcaccgg caaggugaac aagaucacca ucaccaacga caagggcaga cugagcaagg     1620

aggagaucga gagaauggug cuggacgccg agaaguacaa ggccgaggac gaggugcaga     1680

gagagaagau cgccgccaag aacgcccugg agagcuacgc cuucaacaug aagagcgugg     1740

ugagcgacga gggccugaag ggcaagauca gcgagagcga caagaacaag auccuggaca     1800

agugcaacga gcugcugagc uggcuggagg ugaaccagcu ggccgagaag gacgaguucg     1860

accacaagag aaaggagcug gagcagaugu gcaaccccau caucaccaag cuguaccagg     1920

gcggcugcac cggccccgcc ugcggcaccg gcuacgugcc cggcagaccc gccaccggcc     1980

ccaccaucga ggagguggac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6644
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt4)

<400>  6644
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgccagag gccccgccau cggcaucgac cugggcacca      120

ccuacagcug cgugggcgug uuccagcacg gcaaggugga gaucaucgcc aacgaccagg      180

gcaacagaac cacccccagc uacguggccu ucaccgacac cgagagacug aucggcgacg      240

ccgccaagaa ccagguggcc augaacccca ccaacaccau cuucgacgcc aagagacuga      300

ucggcagaaa guucgaggac gccaccgugc agagcgacau gaagcacugg cccuucagag      360

uggugagcga gggcggcaag cccaaggugc agguggagua caagggcgag accaagaccu      420

ucuuccccga ggagaucagc agcauggugc ugaccaagau gaaggagauc gccgaggccu      480

accugggcgg caaggugcac agcgccguga ucaccgugcc cgccuacuuc aacgacagcc      540

agagacaggc caccaaggac gccggcacca ucaccggccu gaacgugcug agaaucauca      600

acgagcccac cgccgccgcc aucgccuacg gccuggacaa gaagggcugc gccggcggcg      660

agaagaacgu gcugaucuuc gaccugggcg gcggcaccuu cgacgugagc auccugacca      720

ucgaggacgg caucuucgag gugaagagca ccgccggcga cacccaccug ggcggcgagg      780

acuucgacaa cagaauggug agccaccugg ccgaggaguu caagagaaag cacaagaagg      840

acaucggccc caacaagaga gccgugagaa gacugagaac cgccugcgag agagccaaga      900

gaacccugag cagcagcacc caggccagca ucgagaucga cagccuguac gagggcgugg      960

acuucuacac cagcaucacc agagccagau ucgaggagcu gaacgccgac cuguucagag     1020

gcacccugga gcccguggag aaggcccuga gagacgccaa gcuggacaag ggccagaucc     1080

aggagaucgu gcuggugggc ggcagcacca gaauccccaa gauccagaag cugcugcagg     1140

acuucuucaa cggcaaggag cugaacaaga gcaucaaccc cgacgaggcc guggccuacg     1200

gcgccgccgu gcaggccgcc auccugaucg gcgacaagag cgagaacgug caggaccugc     1260

ugcugcugga cgugaccccc cugagccugg gcaucgagac cgccggcggc gugaugaccc     1320

cccugaucaa gagaaacacc accaucccca ccaagcagac ccagaccuuc accaccuaca     1380

gcgacaacca gagcagcgug cuggugcagg uguacgaggg cgagagagcc augaccaagg     1440

acaacaaccu gcugggcaag uucgaccuga ccggcauccc ccccgccccc agaggcgugc     1500

cccagaucga ggugaccuuc gacaucgacg ccaacggcau ccugaacgug accgccgccg     1560

acaagagcac cggcaaggag aacaagauca ccaucaccaa cgacaagggc agacugagca     1620

aggacgacau cgacagaaug gugcaggagg ccgagagaua caagagcgag gacgaggcca     1680

acagagacag aguggccgcc aagaacgccc uggagagcua caccuacaac aucaagcaga     1740

ccguggagga cgagaagcug agaggcaaga ucagcgagca ggacaagaac aagauccugg     1800

acaagugcca ggaggugauc aacuggcugg acagaaacca gauggccgag aaggacgagu     1860

acgagcacaa gcagaaggag cuggagagag ugugcaaccc caucaucagc aagcuguacc     1920

agggcggccc cggcggcggc agcggcggcg gcggcagcgg cgccagcggc ggccccacca     1980

ucgaggaggu ggacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  6645
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt4)

<400>  6645
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggugg gcaucgaccu gggcuuccag agcugcuacg      120

uggccguggc cagagccggc ggcaucgaga ccaucgccaa cgaguacagc gacagaugca      180

cccccgccug caucagcuuc ggccccaaga acagaagcau cggcgccgcc gccaagagcc      240

aggugaucag caacgccaag aacaccgugc agggcuucaa gagauuccac ggcagagccu      300

ucagcgaccc cuucguggag gccgagaaga gcaaccuggc cuacgacauc gugcagcugc      360

ccaccggccu gaccggcauc aaggugaccu acauggagga ggagagaaac uucaccaccg      420

agcaggugac cgccaugcug cugagcaagc ugaaggagac cgccgagagc gugcugaaga      480

agcccguggu ggacugcgug gugagcgugc ccugcuucua caccgacgcc gagagaagaa      540

gcgugaugga cgccacccag aucgccggcc ugaacugccu gagacugaug aacgagacca      600

ccgccguggc ccuggccuac ggcaucuaca agcaggaccu gcccgcccug gaggagaagc      660

ccagaaacgu gguguucgug gacaugggcc acagcgccua ccaggugagc gugugcgccu      720

ucaacagagg caagcugaag gugcuggcca ccgccuucga caccacccug ggcggcagaa      780

aguucgacga ggugcuggug aaccacuucu gcgaggaguu cggcaagaag uacaagcugg      840

acaucaagag caagaucaga gcccugcuga gacugagcca ggagugcgag aagcugaaga      900

agcugaugag cgccaacgcc agcgaccugc cccugagcau cgagugcuuc augaacgacg      960

uggacgugag cggcaccaug aacagaggca aguuccugga gaugugcaac gaccugcugg     1020

ccagagugga gcccccccug agaagcgugc uggagcagac caagcugaag aaggaggaca     1080

ucuacgccgu ggagaucgug ggcggcgcca ccagaauccc cgccgugaag gagaagauca     1140

gcaaguucuu cggcaaggag cugagcacca cccugaacgc cgacgaggcc gugaccagag     1200

gcugcgcccu gcagugcgcc auccugagcc ccgccuucaa ggugagagag uucagcauca     1260

ccgacguggu gcccuacccc aucagccuga gauggaacag ccccgccgag gagggcagca     1320

gcgacugcga gguguucagc aagaaccacg ccgcccccuu cagcaaggug cugaccuucu     1380

acagaaagga gcccuucacc cuggaggccu acuacagcag cccccaggac cugcccuacc     1440

ccgaccccgc caucgcccag uucagcgugc agaaggugac cccccagagc gacggcagca     1500

gcagcaaggu gaaggugaag gugagaguga acgugcacgg caucuucagc gugagcagcg     1560

ccagccuggu ggaggugcac aagagcgagg agaacgagga gcccauggag accgaccaga     1620

acgccaagga ggaggagaag augcaggugg accaggagga gccccacgug gaggagcagc     1680

agcagcagac ccccgccgag aacaaggccg agagcgagga gauggagacc agccaggccg     1740

gcagcaagga caagaagaug gaccagcccc cccaggccaa gaaggccaag gugaagacca     1800

gcaccgugga ccugcccauc gagaaccagc ugcuguggca gaucgacaga gagaugcuga     1860

accuguacau cgagaacgag ggcaagauga ucaugcagga caagcuggag aaggagagaa     1920

acgacgccaa gaacgccgug gaggaguacg uguacgagau gagagacaag cugagcggcg     1980

aguacgagaa guucgugagc gaggacgaca gaaacagcuu cacccugaag cuggaggaca     2040

ccgagaacug gcuguacgag gacggcgagg accagcccaa gcagguguac guggacaagc     2100

uggccgagcu gaagaaccug ggccagccca ucaagaucag auuccaggag agcgaggaga     2160

gacccaagcu guucgaggag cugggcaagc agauccagca guacaugaag aucaucagca     2220

gcuucaagaa caaggaggac caguacgacc accuggacgc cgccgacaug accaaggugg     2280

agaagagcac caacgaggcc auggagugga ugaacaacaa gcugaaccug cagaacaagc     2340

agagccugac cauggacccc guggugaaga gcaaggagau cgaggccaag aucaaggagc     2400

ugaccagcac cugcagcccc aucaucagca agcccaagcc caagguggag ccccccaagg     2460

aggagcagaa gaacgccgag cagaacggcc ccguggacgg ccagggcgac aaccccggcc     2520

cccaggccgc cgagcagggc accgacaccg ccgugcccag cgacagcgac aagaagcugc     2580

ccgagaugga caucgacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  6646
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt4)

<400>  6646
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggugg gcaucgaccu gggcuuccug aacugcuaca      120

ucgccguggc cagaagcggc ggcaucgaga ccaucgccaa cgaguacagc gacagaugca      180

cccccgccug caucagccug ggcagcagaa ccagagccau cggcaacgcc gccaagagcc      240

agaucgugac caacgugaga aacaccaucc acggcuucaa gaagcugcac ggcagaagcu      300

ucgacgaccc caucgugcag accgagagaa ucagacugcc cuacgagcug cagaagaugc      360

ccaacggcag cgccggcgug aaggugagau accuggagga ggagagaccc uucgccaucg      420

agcaggugac cggcaugcug cuggccaagc ugaaggagac cagcgagaac gcccugaaga      480

agcccguggc cgacugcgug aucagcaucc ccagcuucuu caccgacgcc gagagaagaa      540

gcgugauggc cgccgcccag guggccggcc ugaacugccu gagacugaug aacgagacca      600

ccgccguggc ccuggccuac ggcaucuaca agcaggaccu gcccccccug gacgagaagc      660

ccagaaacgu gguguucauc gacaugggcc acagcgccua ccaggugcug gugugcgccu      720

ucaacaaggg caagcugaag gugcuggcca ccaccuucga ccccuaccug ggcggcagaa      780

acuucgacga ggcccuggug gacuacuucu gcgacgaguu caagaccaag uacaagauca      840

acgugaagga gaacagcaga gcccugcuga gacuguacca ggagugcgag aagcugaaga      900

agcugaugag cgccaacgcc agcgaccugc cccugaacau cgagugcuuc augaacgacc      960

uggacgugag cagcaagaug aacagagccc aguucgagca gcugugcgcc agccugcugg     1020

ccagagugga gcccccccug aaggccguga uggagcaggc caaccugcag agagaggaca     1080

ucagcagcau cgagaucgug ggcggcgcca ccagaauccc cgccgugaag gagcagauca     1140

ccaaguucuu ccugaaggac aucagcacca cccugaacgc cgacgaggcc guggccagag     1200

gcugcgcccu gcagugcgcc auccugagcc ccgccuucaa ggugagagag uucagcauca     1260

ccgaccuggu gcccuacagc aucacccuga gauggaagac cagcuucgag gacggcagcg     1320

gcgagugcga gguguucugc aagaaccacc ccgcccccuu cagcaaggug aucaccuucc     1380

acaagaagga gcccuucgag cuggaggccu ucuacaccaa ccugcacgag gugcccuacc     1440

ccgacgccag aaucggcagc uucaccaucc agaacguguu cccccagagc gacggcgaca     1500

gcagcaaggu gaaggugaag gugagaguga acauccacgg caucuucagc guggccagcg     1560

ccagcgugau cgagaagcag aaccuggagg gcgaccacag cgacgccccc auggagaccg     1620

agaccagcuu caagaacgag aacaaggaca acauggacaa gaugcaggug gaccaggagg     1680

agggccacca gaagugccac gccgagcaca cccccgagga ggagaucgac cacaccggcg     1740

ccaagaccaa gagcgccgug agcgacaagc aggacagacu gaaccagacc cugaagaagg     1800

gcaaggugaa gagcaucgac cugcccaucc agagcagccu gugcagacag cugggccagg     1860

accugcugaa cagcuacauc gagaacgagg gcaagaugau caugcaggac aagcuggaga     1920

aggagagaaa cgacgccaag aacgccgugg aggaguacgu guacgacuuc agagacagac     1980

ugggcaccgu guacgagaag uucaucaccc ccgaggaccu gagcaagcug agcgccgugc     2040

uggaggacac cgagaacugg cuguacgagg acggcgagga ccagcccaag cagguguacg     2100

uggacaagcu gcaggagcug aagaaguacg gccagcccau ccagaugaag uacauggagc     2160

acgaggagag acccaaggcc cugaacgacc ugggcaagaa gauccagcug gugaugaagg     2220

ugaucgaggc cuacagaaac aaggacgaga gauacgacca ccuggacccc accgagaugg     2280

agaaggugga gaagugcauc agcgacgcca ugagcuggcu gaacagcaag augaacgccc     2340

agaacaagcu gagccugacc caggaccccg uggugaaggu gagcgagauc guggccaaga     2400

gcaaggagcu ggacaacuuc ugcaacccca ucaucuacaa gcccaagccc aaggccgagg     2460

ugcccgagga caagcccaag gccaacagcg agcacaacgg ccccauggac ggccagagcg     2520

gcaccgagac caagagcgac agcaccaagg acagcagcca gcacaccaag agcagcggcg     2580

agauggaggu ggacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  6647
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt4)

<400>  6647
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugagcc ugguggccgc caugcugcug cugcugagcg      120

ccgccagagc cgaggaggag gacaagaagg aggacguggg caccguggug ggcaucgacc      180

ugggcaccac cuacagcugc gugggcgugu ucaagaacgg cagaguggag aucaucgcca      240

acgaccaggg caacagaauc acccccagcu acguggccuu cacccccgag ggcgagagac      300

ugaucggcga cgccgccaag aaccagcuga ccagcaaccc cgagaacacc guguucgacg      360

ccaagagacu gaucggcaga accuggaacg accccagcgu gcagcaggac aucaaguucc      420

ugcccuucaa ggugguggag aagaagacca agcccuacau ccagguggac aucggcggcg      480

gccagaccaa gaccuucgcc cccgaggaga ucagcgccau ggugcugacc aagaugaagg      540

agaccgccga ggccuaccug ggcaagaagg ugacccacgc cguggugacc gugcccgccu      600

acuucaacga cgcccagaga caggccacca aggacgccgg caccaucgcc ggccugaacg      660

ugaugagaau caucaacgag cccaccgccg ccgccaucgc cuacggccug gacaagagag      720

agggcgagaa gaacauccug guguucgacc ugggcggcgg caccuucgac gugagccugc      780

ugaccaucga caacggcgug uucgaggugg uggccaccaa cggcgacacc caccugggcg      840

gcgaggacuu cgaccagaga gugauggagc acuucaucaa gcuguacaag aagaagaccg      900

gcaaggacgu gagaaaggac aacagagccg ugcagaagcu gagaagagag guggagaagg      960

ccaagagagc ccugagcagc cagcaccagg ccagaaucga gaucgagagc uucuacgagg     1020

gcgaggacuu cagcgagacc cugaccagag ccaaguucga ggagcugaac auggaccugu     1080

ucagaagcac caugaagccc gugcagaagg ugcuggagga cagcgaccug aagaagagcg     1140

acaucgacga gaucgugcug gugggcggca gcaccagaau ccccaagauc cagcagcugg     1200

ugaaggaguu cuucaacggc aaggagccca gcagaggcau caaccccgac gaggccgugg     1260

ccuacggcgc cgccgugcag gccggcgugc ugagcggcga ccaggacacc ggcgaccugg     1320

ugcugcugga cgugugcccc cugacccugg gcaucgagac cgugggcggc gugaugacca     1380

agcugauccc cagaaacacc guggugccca ccaagaagag ccagaucuuc agcaccgcca     1440

gcgacaacca gcccaccgug accaucaagg uguacgaggg cgagagaccc cugaccaagg     1500

acaaccaccu gcugggcacc uucgaccuga ccggcauccc ccccgccccc agaggcgugc     1560

cccagaucga ggugaccuuc gagaucgacg ugaacggcau ccugagagug accgccgagg     1620

acaagggcac cggcaacaag aacaagauca ccaucaccaa cgaccagaac agacugaccc     1680

ccgaggagau cgagagaaug gugaacgacg ccgagaaguu cgccgaggag gacaagaagc     1740

ugaaggagag aaucgacacc agaaacgagc uggagagcua cgccuacagc cugaagaacc     1800

agaucggcga caaggagaag cugggcggca agcugagcag cgaggacaag gagaccaugg     1860

agaaggccgu ggaggagaag aucgaguggc uggagagcca ccaggacgcc gacaucgagg     1920

acuucaaggc caagaagaag gagcuggagg agaucgugca gcccaucauc agcaagcugu     1980

acggcagcgc cggccccccc cccaccggcg aggaggacac cgccgagaag gacgagcugu     2040

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  6648
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt4)

<400>  6648
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gagagcuggc cgugggcauc gaccugggca      120

ccaccuacag cugcgugggc guguuccagc agggcagagu ggagauccug gccaacgacc      180

agggcaacag aaccaccccc agcuacgugg ccuucaccga caccgagaga cuggugggcg      240

acgccgccaa gagccaggcc gcccugaacc cccacaacac cguguucgac gccaagagac      300

ugaucggcag aaaguucgcc gacaccaccg ugcagagcga caugaagcac uggcccuuca      360

gaguggugag cgagggcggc aagcccaagg ugagagugug cuacagaggc gaggacaaga      420

ccuucuaccc cgaggagauc agcagcaugg ugcugagcaa gaugaaggag accgccgagg      480

ccuaccuggg ccagcccgug aagcacgccg ugaucaccgu gcccgccuac uucaacgaca      540

gccagagaca ggccaccaag gacgccggcg ccaucgccgg ccugaacgug cugagaauca      600

ucaacgagcc caccgccgcc gccaucgccu acggccugga cagaagaggc gccggcgaga      660

gaaacgugcu gaucuucgac cugggcggcg gcaccuucga cgugagcgug cugagcaucg      720

acgccggcgu guucgaggug aaggccaccg ccggcgacac ccaccugggc ggcgaggacu      780

ucgacaacag acuggugaac cacuucaugg aggaguucag aagaaagcac ggcaaggacc      840

ugagcggcaa caagagagcc cugagaagac ugagaaccgc cugcgagaga gccaagagaa      900

cccugagcag cagcacccag gccacccugg agaucgacag ccuguucgag ggcguggacu      960

ucuacaccag caucaccaga gccagauucg aggagcugug cagcgaccug uucagaagca     1020

cccuggagcc cguggagaag gcccugagag acgccaagcu ggacaaggcc cagauccacg     1080

acguggugcu ggugggcggc agcaccagaa uccccaaggu gcagaagcug cugcaggacu     1140

ucuucaacgg caaggagcug aacaagagca ucaaccccga cgaggccgug gccuacggcg     1200

ccgccgugca ggccgccgug cugaugggcg acaagugcga gaaggugcag gaccugcugc     1260

ugcuggacgu ggccccccug agccugggcc uggagaccgc cggcggcgug augaccaccc     1320

ugauccagag aaacgccacc auccccacca agcagaccca gaccuucacc accuacagcg     1380

acaaccagcc cggcguguuc auccaggugu acgagggcga gagagccaug accaaggaca     1440

acaaccugcu gggcagauuc gagcugagcg gcaucccccc cgcccccaga ggcgugcccc     1500

agaucgaggu gaccuucgac aucgacgcca acggcauccu gagcgugacc gccaccgaca     1560

gaagcaccgg caaggccaac aagaucacca ucaccaacga caagggcaga cugagcaagg     1620

aggaggugga gagaauggug cacgaggccg agcaguacaa ggccgaggac gaggcccaga     1680

gagacagagu ggccgccaag aacagccugg aggcccacgu guuccacgug aagggcagcc     1740

ugcaggagga gagccugaga gacaagaucc ccgaggagga cagaagaaag augcaggaca     1800

agugcagaga ggugcuggcc uggcuggagc acaaccagcu ggccgagaag gaggaguacg     1860

agcaccagaa gagagagcug gagcagaucu gcagacccau cuucagcaga cuguacggcg     1920

gccccggcgu gcccggcggc agcagcugcg gcacccaggc cagacagggc gaccccagca     1980

ccggccccau caucgaggag guggacugag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  6649
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt4)

<400>  6649
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gagagcuggc cgugggcauc gaccugggca      120

ccaccuacag cugcgugggc guguuccagc agggcagagu ggagauccug gccaacgacc      180

agggcaacag aaccaccccc agcuacgugg ccuucaccga caccgagaga cuggugggcg      240

acgccgccaa gagccaggcc gcccugaacc cccacaacac cguguucgac gccaagagac      300

ugaucggcag aaaguucgcc gacaccaccg ugcagagcga caugaagcac uggcccuucc      360

agguggugag cgagggcggc aagcccaagg ugagagugug cuacagaggc gaggacaaga      420

ccuucuaccc cgaggagauc agcagcaugg ugcugagcaa gaugaaggag accgccgagg      480

ccuaccuggg ccagcccgug aagcacgccg ugaucaccgu gcccaccuac uucagcaaca      540

gccagagaca ggccaccaag gacgccggcg ccaucgccgg ccugaaggug cugcccauca      600

ucaacgaggc caccgccgcc gccaucgccu acggccugga cagaagaggc gccggcaaga      660

gaaacgugcu gaucuucgac cugggcggcg gcaccuucga cgugagcgug cugagcaucg      720

acgccggcgu guucgaggug aaggccaccg ccggcgacac ccaccugggc ggcgaggacu      780

ucgacaacag acuggugaac cacuucaugg aggaguucag aagaaagcac ggcaaggacc      840

ugagcggcaa caagagagcc cugagaagac ugagaaccgc cugcgagaga gccaagagaa      900

cccccagcag cagcacccag gccacccugg agaucgacag ccuguucgag ggcguggacu      960

ucuacaagag caucaccaga gccagauucg aggagcugug cagcgaccug uucagaagca     1020

cccuggagcc cguggagaag gcccugagag acgccaagcu ggacaaggcc cagauccacg     1080

acuucgugcu gggcggcggc cugcacagcc acccccaggg cgccgaggug gccgccggcc     1140

ugcugcagag acagggcgcc gagcaggagc accagcccug aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  6650
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt4)

<400>  6650
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaagggcc ccgccguggg caucgaccug ggcaccaccu      120

acagcugcgu gggcguguuc cagcacggca agguggagau caucgccaac gaccagggca      180

acagaaccac ccccagcuac guggccuuca ccgacaccga gagacugauc ggcgacgccg      240

ccaagaacca gguggccaug aaccccacca acaccguguu cgacgccaag agacugaucg      300

gcagaagauu cgacgacgcc guggugcaga gcgacaugaa gcacuggccc uucauggugg      360

ugaacgacgc cggcagaccc aaggugcagg uggaguacaa gggcgagacc aagagcuucu      420

accccgagga ggugagcagc auggugcuga ccaagaugaa ggagaucgcc gaggccuacc      480

ugggcaagac cgugaccaac gccgugguga ccgugcccgc cuacuucaac gacagccaga      540

gacaggccac caaggacgcc ggcaccaucg ccggccugaa cgugcugaga aucaucaacg      600

agcccaccgc cgccgccauc gccuacggcc uggacaagaa ggugggcgcc gagagaaacg      660

ugcugaucuu cgaccugggc ggcggcaccu ucgacgugag cauccugacc aucgaggacg      720

gcaucuucga ggugaagagc accgccggcg acacccaccu gggcggcgag gacuucgaca      780

acagaauggu gaaccacuuc aucgccgagu ucaagagaaa gcacaagaag gacaucagcg      840

agaacaagag agccgugaga agacugagaa ccgccugcga gagagccaag agaacccuga      900

gcagcagcac ccaggccagc aucgagaucg acagccugua cgagggcauc gacuucuaca      960

ccagcaucac cagagccaga uucgaggagc ugaacgccga ccuguucaga ggcacccugg     1020

accccgugga gaaggcccug agagacgcca agcuggacaa gagccagauc cacgacaucg     1080

ugcugguggg cggcagcacc agaaucccca agauccagaa gcugcugcag gacuucuuca     1140

acggcaagga gcugaacaag agcaucaacc ccgacgaggc cguggccuac ggcgccgccg     1200

ugcaggccgc cauccugagc ggcgacaaga gcgagaacgu gcaggaccug cugcugcugg     1260

acgugacccc ccugagccug ggcaucgaga ccgccggcgg cgugaugacc gugcugauca     1320

agagaaacac caccaucccc accaagcaga cccagaccuu caccaccuac agcgacaacc     1380

agcccggcgu gcugauccag guguacgagg gcgagagagc caugaccaag gacaacaacc     1440

ugcugggcaa guucgagcug accggcaucc cccccgcccc cagaggcgug ccccagaucg     1500

aggugaccuu cgacaucgac gccaacggca uccugaacgu gagcgccgug gacaagagca     1560

ccggcaagga gaacaagauc accaucacca acgacaaggg cagacugagc aaggaggaca     1620

ucgagagaau ggugcaggag gccgagaagu acaaggccga ggacgagaag cagagagaca     1680

aggugagcag caagaacagc cuggagagcu acgccuucaa caugaaggcc accguggagg     1740

acgagaagcu gcagggcaag aucaacgacg aggacaagca gaagauccug gacaagugca     1800

acgagaucau caacuggcug gacaagaacc agaccgccga gaaggaggag uucgagcacc     1860

agcagaagga gcuggagaag gugugcaacc ccaucaucac caagcuguac cagagcgccg     1920

gcggcaugcc cggcggcaug cccggcggcu uccccggcgg cggcgccccc cccagcggcg     1980

gcgccagcag cggccccacc aucgaggagg uggacugagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  6651
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt4)

<400>  6651
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucagcgcca gcagagccgc cgccgccaga cuggugggcg      120

ccgccgccag cagaggcccc accgccgcca gacaccagga cagcuggaac ggccugagcc      180

acgaggccuu cagacuggug agcagaagag acuacgccag cgaggccauc aagggcgccg      240

uggugggcau cgaccugggc accaccaaca gcugcguggc cgugauggag ggcaagcagg      300

ccaaggugcu ggagaacgcc gagggcgcca gaaccacccc cagcguggug gccuucaccg      360

ccgacggcga gagacuggug ggcaugcccg ccaagagaca ggccgugacc aaccccaaca      420

acaccuucua cgccaccaag agacugaucg gcagaagaua cgacgacccc gaggugcaga      480

aggacaucaa gaacgugccc uucaagaucg ugagagccag caacggcgac gccugggugg      540

aggcccacgg caagcuguac agccccagcc agaucggcgc cuucgugcug augaagauga      600

aggagaccgc cgagaacuac cugggccaca ccgccaagaa cgccgugauc accgugcccg      660

ccuacuucaa cgacagccag agacaggcca ccaaggacgc cggccagauc agcggccuga      720

acgugcugag agugaucaac gagcccaccg ccgccgcccu ggccuacggc cuggacaaga      780

gcgaggacaa ggugaucgcc guguacgacc ugggcggcgg caccuucgac aucagcaucc      840

uggagaucca gaagggcgug uucgagguga agagcaccaa cggcgacacc uuccugggcg      900

gcgaggacuu cgaccaggcc cugcugagac acaucgugaa ggaguucaag agagagaccg      960

gcguggaccu gaccaaggac aacauggccc ugcagagagu gagagaggcc gccgagaagg     1020

ccaagugcga gcugagcagc agcgugcaga ccgacaucaa ccugcccuac cugaccaugg     1080

acagcagcgg ccccaagcac cugaacauga agcugaccag agcccaguuc gagggcaucg     1140

ugaccgaccu gaucagaaga accaucgccc ccugccagaa ggccaugcag gacgccgagg     1200

ugagcaagag cgacaucggc gaggugaucc uggugggcgg caugaccaga augcccaagg     1260

ugcagcagac cgugcaggac cuguucggca gagcccccag caaggccgug aaccccgacg     1320

aggccguggc caucggcgcc gccauccagg gcggcgugcu ggccggcgac gugaccgacg     1380

ugcugcugcu ggacgugacc ccccugagcc ugggcaucga gacccugggc ggcguguuca     1440

ccaagcugau caacagaaac accaccaucc ccaccaagaa gagccaggug uucagcaccg     1500

ccgccgacgg ccagacccag guggagauca aggugugcca gggcgagaga gagauggccg     1560

gcgacaacaa gcugcugggc caguucaccc ugaucggcau cccccccgcc cccagaggcg     1620

ugccccagau cgaggugacc uucgacaucg acgccaacgg caucgugcac gugagcgcca     1680

aggacaaggg caccggcaga gagcagcaga ucgugaucca gagcagcggc ggccugagca     1740

aggacgacau cgagaacaug gugaagaacg ccgagaagua cgccgaggag gacagaagaa     1800

agaaggagag aguggaggcc gugaacaugg ccgagggcau cauccacgac accgagacca     1860

agauggagga guucaaggac cagcugcccg ccgacgagug caacaagcug aaggaggaga     1920

ucagcaagau gagagagcug cuggccagaa aggacagcga gaccggcgag aacaucagac     1980

aggccgccag cagccugcag caggccagcc ugaagcuguu cgagauggcc uacaagaaga     2040

uggccagcga gagagagggc agcggcagca gcggcaccgg cgagcagaag gaggaccaga     2100

aggaggagaa gcagugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  6652
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt4)

<400>  6652
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg aggccggcgg cagcgacggc cccagagaga      120

ccgcccccac cagcgccuac agcagccccg ccagaagccu gggcgacacc ggcaucaccc      180

cccugagccc cagccacauc gugaacgaca ccgacagcaa cgugagcgag cagcagagcu      240

uccugguggu gguggccgug gacuucggca ccaccagcag cggcuacgcc uacagcuuca      300

ccaaggagcc cgagugcauc cacgugauga gaagauggga gggcggcgac cccggcguga      360

gcaaccagaa gacccccacc accauccugc ugacccccga gagaaaguuc cacagcuucg      420

gcuacgccgc cagagacuuc uaccacgacc uggaccccaa cgaggccaag caguggcugu      480

accuggagaa guucaagaug aagcugcaca ccaccggcga ccugaccaug gacaccgacc      540

ugaccgccgc caacggcaag aaggugaagg cccuggagau cuucgccuac gcccugcagu      600

acuucaagga gcaggcccug aaggagcuga gcgaccaggc cggcagcgag uucgagaaca      660

gcgacgugag augggugauc accgugcccg ccaucuggaa gcagcccgcc aagcaguuca      720

ugagacaggc cgccuaccag gccggccugg ccagccccga gaacagcgag cagcugauca      780

ucgcccugga gcccgaggcc gccagcaucu acugcagaaa gcugagacug caccagauga      840

ucgagcugag cagcaaggcc gccgugaacg gcuacagcgg cagcgacacc gugggcgccg      900

gcuucaccca ggccaaggag cacaucagaa gaaacagaca gagcagaacc uuccuggugg      960

agaacgugau cggcgagauc uggagcgagc uggaggaggg cgacaaguac gugguggugg     1020

acagcggcgg cggcaccgug gaccugaccg ugcaccagau cagacugccc gagggccacc     1080

ugaaggagcu guacaaggcc accggcggcc ccuacggcag ccugggcgug gacuacgagu     1140

ucgagaagcu gcuguacaag aucuucggcg aggacuucau cgagcaguuc aagaucaaga     1200

gacccgccgc cuggguggac cugaugaucg ccuucgagag cagaaagaga gccgccgccc     1260

ccgacagaac caacccccug aacaucaccc ugcccuucag cuucaucgac uacuacaaga     1320

aguucagagg ccacagcgug gagcacgccc ugagaaagag caacguggac uucgugaagu     1380

ggagcagcca gggcaugcug agaaugagcc ccgacgccau gaacgcccug uucaagccca     1440

ccaucgacag caucaucgag caccugagag accuguucca gaagcccgag gugagcaccg     1500

ugaaguuccu guuccuggug ggcggcuucg ccgaggcccc ccugcugcag caggccgugc     1560

aggccgccuu cggcgaccag ugcagaauca ucauccccca ggacgugggc cugaccaucc     1620

ugaagggcgc cgugcuguuc ggccuggacc ccgccgugau caaggugaga agaagccccc     1680

ugaccuacgg cgugggcgug cugaacagau acguggaggg caagcacccc cccgagaagc     1740

ugcuggugaa ggacggcacc agauggugca ccgacguguu cgacaaguuc aucagcgccg     1800

accagagcgu ggcccugggc gagcugguga agagaagcua cacccccgcc aagcccagcc     1860

agcuggugau cgugaucaac aucuacagca gcgagcacga caacgugagc uucaucaccg     1920

accccggcgu gaagaagugc ggcacccuga gacuggaccu gaccggcacc agcggcaccg     1980

ccgugcccgc cagaagagag auccagaccc ugaugcaguu cggcgacacc gagaucaagg     2040

ccaccgccau cgacaucgcc accagcaaga gcgugaaggu gggcaucgac uuccugaacu     2100

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  6653
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt4)

<400>  6653
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuggccgugc ccgagauggg ccugcagggc cuguacaucg      120

gcagcagccc cgagagaagc cccgugccca gcccccccgg cagccccaga acccaggaga      180

gcugcggcau cgccccccug acccccagcc agagccccaa gcccgaggug agagcccccc      240

agcaggccag cuucagcgug gugguggcca ucgacuucgg caccaccagc agcggcuacg      300

ccuucagcuu cgccagcgac cccgaggcca uccacaugau gagaaagugg gagggcggcg      360

accccggcgu ggcccaccag aagaccccca ccugccugcu gcugaccccc gagggcgccu      420

uccacagcuu cggcuacacc gccagagacu acuaccacga ccuggacccc gaggaggcca      480

gagacuggcu guacuucgag aaguucaaga ugaagaucca cagcgccacc gaccugaccc      540

ugaagaccca gcuggaggcc gugaacggca agaccaugcc cgcccuggag guguucgccc      600

acgcccugag auucuucaga gagcacgccc ugcaggagcu gagagagcag agccccagcc      660

ugcccgagaa ggacaccgug agaugggugc ugaccgugcc cgccaucugg aagcagcccg      720

ccaagcaguu caugagagag gccgccuacc uggccggccu ggugagcaga gagaacgccg      780

agcagcugcu gaucgcccug gagcccgagg ccgccagcgu guacugcaga aagcugagac      840

ugcaccagcu gcuggaccug agcggcagag cccccggcgg cggcagacug ggcgagagaa      900

gaagcaucga cagcagcuuc agacaggcca gagagcagcu gagaagaagc agacacagca      960

gaaccuuccu gguggagagc ggcgugggcg agcugugggc cgagaugcag gccggcgaca     1020

gauacguggu ggccgacugc ggcggcggca ccguggaccu gaccgugcac cagcuggagc     1080

agccccacgg cacccugaag gagcuguaca aggccagcgg cggccccuac ggcgccgugg     1140

gcguggaccu ggccuucgag cagcugcugu gcagaaucuu cggcgaggac uucaucgcca     1200

ccuucaagag acagagaccc gccgccuggg uggaccugac caucgccuuc gaggccagaa     1260

agagaaccgc cggcccccac agagccggcg cccugaacau cagccugccc uucagcuuca     1320

ucgacuucua cagaaagcag agaggccaca acguggagac cgcccugaga agaagcagcg     1380

ugaacuucgu gaaguggagc agccagggca ugcugagaau gagcugcgag gccaugaacg     1440

agcuguucca gcccaccgug agcggcauca uccagcacau cgaggcccug cuggccagac     1500

ccgaggugca gggcgugaag cugcuguucc uggugggcgg cuucgccgag agcgccgugc     1560

ugcagcacgc cgugcaggcc gcccugggcg ccagaggccu gagaguggug gugccccacg     1620

acgugggccu gaccauccug aagggcgccg ugcuguucgg ccaggccccc ggcgugguga     1680

gagugagaag aagcccccug accuacggcg ugggcgugcu gaacagauuc gugcccggca     1740

gacacccccc cgagaagcug cuggugagag acggcagaag auggugcacc gacguguucg     1800

agagauucgu ggccgccgag cagagcgugg cccugggcga ggaggugaga agaagcuacu     1860

gccccgccag acccggccag agaagagugc ugaucaaccu guacugcugc gccgccgagg     1920

acgccagauu caucaccgac cccggcguga gaaagugcgg cgcccugagc cuggagcugg     1980

agcccgccga cugcggccag gacaccgccg gcgccccccc cggcagaaga gagaucagag     2040

ccgccaugca guucggcgac accgagauca aggugaccgc cguggacgug agcaccaaca     2100

gaagcgugag agccagcauc gacuuccuga gcaacugagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  6654
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt4)

<400>  6654
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagagaga ugaccauccu gggcagcgcc gugcugaccc      120

ugcugcuggc cggcuaccug gcccagcagu accugccccu gcccaccccc aaggugaucg      180

gcaucgaccu gggcaccacc uacugcagcg ugggcguguu cuuccccggc accggcaagg      240

ugaaggugau ccccgacgag aacggccaca ucagcauccc cagcauggug agcuucaccg      300

acaacgacgu guacgugggc uacgagagcg uggagcuggc cgacagcaac ccccagaaca      360

ccaucuacga cgccaagaga uucaucggca agaucuucac cgccgaggag cuggaggccg      420

agaucggcag auaccccuuc aaggugcuga acaagaacgg caugguggag uucagcguga      480

ccagcaacga gaccaucacc gugagccccg aguacguggg cagcagacug cugcugaagc      540

ugaaggagau ggccgaggcc uaccugggca ugcccguggc caacgccgug aucagcgugc      600

ccgccgaguu cgaccugaag cagagaaaca gcaccaucga ggccgccaac cuggccggcc      660

ugaagauccu gagagugauc aacgagccca ccgccgccgc cauggccuac ggccugcaca      720

aggccgacgu guuccacgug cuggugaucg accugggcgg cggcacccug gacgugagcc      780

ugcugaacaa gcagggcggc auguuccuga ccagagccau gagcggcaac aacaagcugg      840

gcggccagga cuucaaccag agacugcugc aguaccugua caagcagauc uaccagaccu      900

acggcuucgu gcccagcaga aaggaggaga uccacagacu gagacaggcc guggagaugg      960

ugaagcugaa ccugacccug caccagagcg cccagcugag cgugcugcug accguggagg     1020

agcaggacag aaaggagccc cacagcagcg acaccgagcu gcccaaggac aagcugagca     1080

gcgccgacga ccacagagug aacagcggcu ucggcagagg ccugagcgac aagaagagcg     1140

gcgagagcca ggugcuguuc gagaccgaga ucagcagaaa gcuguucgac acccugaacg     1200

aggaccuguu ccagaagauc cuggugccca uccagcaggu gcugaaggag ggccaccugg     1260

agaagaccga gaucgacgag guggugcugg ugggcggcag caccagaauc cccagaauca     1320

gacaggugau ccaggaguuc uucggcaagg accccaacac cagcguggac cccgaccugg     1380

ccguggugac cggcguggcc auccaggccg gcaucgacgg cggcagcugg ccccugcagg     1440

ugagcgcccu ggagaucccc aacaagcacc ugcagaagac caacuucaac ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6655
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt4)

<400>  6655
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgccaucg gcgugcaccu gggcugcacc agcgccugcg      120

uggccgugua caaggacggc agagccggcg ugguggccaa cgacgccggc gacagaguga      180

cccccgccgu gguggccuac agcgagaacg aggagaucgu gggccuggcc gccaagcaga      240

gcagaaucag aaacaucagc aacaccguga ugaaggugaa gcagauccug ggcagaagca      300

gcagcgaccc ccaggcccag aaguacaucg ccgagagcaa gugccuggug aucgagaaga      360

acggcaagcu gagauacgag aucgacaccg gcgaggagac caaguucgug aaccccgagg      420

acguggccag acugaucuuc agcaagauga aggagaccgc ccacagcgug cugggcagcg      480

acgccaacga cguggugauc accgugcccu ucgacuucgg cgagaagcag aagaacgccc      540

ugggcgaggc cgccagagcc gccggcuuca acgugcugag acugauccac gagcccagcg      600

ccgcccugcu ggccuacggc aucggccagg acagccccac cggcaagagc aacauccugg      660

uguucaagcu gggcggcacc agccugagcc ugagcgugau ggaggugaac agcggcaucu      720

acagagugcu gagcaccaac accgacgaca acaucggcgg cgcccacuuc accgagaccc      780

uggcccagua ccuggccagc gaguuccaga gaagcuucaa gcacgacgug agaggcaacg      840

ccagagccau gaugaagcug accaacagcg ccgagguggc caagcacagc cugagcaccc      900

ugggcagcgc caacugcuuc cuggacagcc uguacgaggg ccaggacuuc gacugcaacg      960

ugagcagagc cagauucgag cugcugugca gcccccuguu caacaagugc aucgaggcca     1020

ucagaggccu gcuggaccag aacggcuuca ccgccgacga caucaacaag guggugcugu     1080

gcggcggcag cagcagaauc cccaagcugc agcagcugau caaggaccug uuccccgccg     1140

uggagcugcu gaacagcauc ccccccgacg aggugauccc caucggcgcc gccaucgagg     1200

ccggcauccu gaucggcaag gagaaccugc ugguggagga cagccugaug aucgagugca     1260

gcgccagaga cauccuggug aagggcgugg acgagagcgg cgccagcaga uucaccgugc     1320

uguuccccag cggcaccccc cugcccgcca gaagacagca cacccugcag gcccccggca     1380

gcaucagcag cgugugccug gagcuguacg agagcgacgg caagaacagc gccaaggagg     1440

agaccaaguu cgcccaggug gugcugcagg accuggacaa gaaggagaac ggccugagag     1500

acauccuggc cgugcugacc augaagagag acggcagccu gcacgugacc ugcaccgacc     1560

aggagaccgg caagugcgag gccaucagca ucgagaucgc cagcugagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  6656
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt4)

<400>  6656
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggugg gccuggacgu gggcagccag agcugcuaca      120

ucgccguggc cagagccggc ggcaucgaga ccaucgccaa cgaguucagc gacagaugca      180

cccccagcgu gaucagcuuc ggcagcaaga acagaaccau cggcguggcc gccaagaacc      240

agcagaucac ccacgccaac aacaccguga gcaacuucaa gagauuccac ggcagagccu      300

ucaacgaccc cuucauccag aaggagaagg agaaccugag cuacgaccug gugccccuga      360

agaacggcgg cgugggcauc aaggugaugu acaugggcga ggagcaccug uucagcgugg      420

agcagaucac cgccaugcug cugaccaagc ugaaggagac cgccgagaac agccugaaga      480

agcccgugac cgacugcgug aucagcgugc ccagcuucuu caccgacgcc gagagaagaa      540

gcgugcugga cgccgcccag aucgugggcc ugaacugccu gagacugaug aacgacauga      600

ccgccguggc ccugaacuac ggcaucuaca agcaggaccu gcccagccug gacgagaagc      660

ccagaaucgu gguguucgug gacaugggcc acagcgccuu ccaggugagc gccugcgccu      720

ucaacaaggg caagcugaag gugcugggca ccgccuucga ccccuuccug ggcggcaaga      780

acuucgacga gaagcuggug gagcacuucu gcgccgaguu caagaccaag uacaagcugg      840

acgccaagag caagaucaga gcccugcuga gacuguacca ggagugcgag aagcugaaga      900

agcugaugag cagcaacagc accgaccugc cccugaacau cgagugcuuc augaacgaca      960

aggacgugag cggcaagaug aacagaagcc aguucgagga gcugugcgcc gagcugcugc     1020

agaagaucga ggugccccug uacagccugc uggagcagac ccaccugaag guggaggacg     1080

ugagcgccgu ggagaucgug ggcggcgcca ccagaauccc cgccgugaag gagagaaucg     1140

ccaaguucuu cggcaaggac aucagcacca cccugaacgc cgacgaggcc guggccagag     1200

gcugcgcccu gcagugcgcc auccugagcc ccgccuucaa ggugagagag uucagcguga     1260

ccgacgccgu gcccuucccc aucagccuga ucuggaacca cgacagcgag gacaccgagg     1320

gcgugcacga gguguucagc agaaaccacg ccgcccccuu cagcaaggug cugaccuucc     1380

ugagaagagg ccccuucgag cuggaggccu ucuacagcga cccccagggc gugcccuacc     1440

ccgaggccaa gaucggcaga uucguggugc agaacgugag cgcccagaag gacggcgaga     1500

agagcagagu gaaggugaag gugagaguga acacccacgg caucuucacc aucagcaccg     1560

ccagcauggu ggagaaggug cccaccgagg agaacgagau gagcagcgag gccgacaugg     1620

agugccugaa ccagagaccc cccgagaacc ccgacaccga caagaacgug cagcaggaca     1680

acagcgaggc cggcacccag ccccaggugc agaccgacgc ccagcagacc agccagagcc     1740

cccccagccc cgagcugacc agcgaggaga acaagauccc cgacgccgac aaggccaacg     1800

agaagaaggu ggaccagccc cccgaggcca agaagcccaa gaucaaggug gugaacgugg     1860

agcugcccau cgaggccaac cugguguggc agcugggcaa ggaccugcug aacauguaca     1920

ucgagaccga gggcaagaug aucaugcagg acaagcugga gaaggagaga aacgacgcca     1980

agaacgccgu ggaggaguac guguacgagu ucagagacaa gcugugcggc cccuacgaga     2040

aguucaucug cgagcaggac caccagaacu uccugagacu gcugaccgag accgaggacu     2100

ggcuguacga ggagggcgag gaccaggcca agcaggccua cguggacaag cuggaggagc     2160

ugaugaagau cggcaccccc gugaagguga gauuccagga ggccgaggag agacccaaga     2220

uguucgagga gcugggccag agacugcagc acuacgccaa gaucgccgcc gacuucagaa     2280

acaaggacga gaaguacaac cacaucgacg agagcgagau gaagaaggug gagaagagcg     2340

ugaacgaggu gauggagugg augaacaacg ugaugaacgc ccaggccaag aagagccugg     2400

accaggaccc cguggugaga gcccaggaga ucaagaccaa gaucaaggag cugaacaaca     2460

ccugcgagcc cguggugacc cagcccaagc ccaagaucga gagccccaag cuggagagaa     2520

cccccaacgg ccccaacauc gacaagaagg aggaggaccu ggaggacaag aacaacuucg     2580

gcgccgagcc cccccaccag aacggcgagu gcuaccccaa cgagaagaac agcgugaaca     2640

uggaccugga cugaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  6657
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt4)

<400>  6657
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg ugagaagaca gagacccaga agaagagugu      120

gcugggcccu gguggccgug cugcuggccg accugcuggc ccugagcgac acccuggccg      180

ugaugagcgu ggaccugggc agcgagagca ugaagguggc caucgugaag cccggcgugc      240

ccauggagau cgugcugaac aaggagagca gaagaaagac ccccgugauc gugacccuga      300

aggagaacga gagauucuuc ggcgacagcg ccgccagcau ggccaucaag aaccccaagg      360

ccacccugag auacuuccag caccugcugg gcaagcaggc cgacaacccc cacguggccc      420

uguaccaggc cagauucccc gagcacgagc ugaccuucga cccccagaga cagaccgugc      480

acuuccagau cagcagccag cugcaguuca gccccgagga ggugcugggc auggugcuga      540

acuacagcag aagccuggcc gaggacuucg ccgagcagcc caucaaggac gccgugauca      600

ccgugcccgu guucuucaac caggccgaga gaagagccgu gcugcaggcc gccagaaugg      660

ccggccugaa ggugcugcag cugaucaacg acaacaccgc caccgcccug agcuacggcg      720

uguucagaag aaaggacauc aacaccaccg cccagaacau cauguucuac gacaugggca      780

gcggcagcac cgugugcacc aucgugaccu accagauggu gaagaccaag gaggccggca      840

ugcagcccca gcugcagauc agaggcgugg gcuucgacag aacccugggc ggccuggaga      900

uggagcugag acugagagag agacuggccg gccuguucaa cgagcagaga aagggccaga      960

gagccaagga cgugagagag aaccccagag ccauggccaa gcugcugaga gaggccaaca     1020

gacugaagac cgugcugagc gccaacgccg accacauggc ccagaucgag ggccugaugg     1080

acgacgugga cuucaaggcc aaggugacca gaguggaguu cgaggagcug ugcgccgacc     1140

uguucgagag agugcccggc cccgugcagc aggcccugca gagcgccgag augagccugg     1200

acgagaucga gcaggugauc cuggugggcg gcgccaccag agugcccaga gugcaggagg     1260

ugcugcugaa ggccgugggc aaggaggagc ugggcaagaa caucaacgcc gacgaggccg     1320

ccgccauggg cgccguguac caggccgccg cccugagcaa ggccuucaag gugaagcccu     1380

ucguggugag agacgccgug guguacccca uccuggugga guucaccaga gagguggagg     1440

aggagcccgg cauccacagc cugaagcaca acaagagagu gcuguucagc agaaugggcc     1500

ccuaccccca gagaaaggug aucaccuuca acagauacag ccacgacuuc aacuuccaca     1560

ucaacuacgg cgaccugggc uuccugggcc ccgaggaccu gagaguguuc ggcagccaga     1620

accugaccac cgugaagcug aagggcgugg gcgacagcuu caagaaguac cccgacuacg     1680

agagcaaggg caucaaggcc cacuucaacc uggacgagag cggcgugcug agccuggaca     1740

gaguggagag cguguucgag acccuggugg aggacagcgc cgaggaggag agcacccuga     1800

ccaagcuggg caacaccauc agcagccugu ucggcggcgg caccaccccc gacgccaagg     1860

agaacggcac cgacaccgug caggaggagg aggagagccc cgccgagggc agcaaggacg     1920

agcccggcga gcagguggag cugaaggagg aggccgaggc ccccguggag gacggcagcc     1980

agcccccccc ccccgagccc aagggcgacg ccacccccga gggcgagaag gccaccgaga     2040

aggagaacgg cgacaagagc gaggcccaga agcccagcga gaaggccgag gccggccccg     2100

agggcguggc ccccgccccc gagggcgaga agaagcagaa gcccgccaga aagagaagaa     2160

ugguggagga gaucggcgug gagcuggugg ugcuggaccu gcccgaccug cccgaggaca     2220

agcuggccca gagcgugcag aagcugcagg accugacccu gagagaccug gagaagcagg     2280

agagagagaa ggccgccaac agccuggagg ccuucaucuu cgagacccag gacaagcugu     2340

accagcccga guaccaggag gugagcaccg aggagcagag agaggagauc agcggcaagc     2400

ugagcgccgc cagcaccugg cuggaggacg agggcguggg cgccaccacc gugaugcuga     2460

aggagaagcu ggccgagcug agaaagcugu gccagggccu guucuucaga guggaggaga     2520

gaaagaagug gcccgagaga cugagcgccc uggacaaccu gcugaaccac agcagcaugu     2580

uccugaaggg cgccagacug auccccgaga uggaccagau cuucaccgag guggagauga     2640

ccacccugga gaaggugauc aacgagaccu gggccuggaa gaacgccacc cuggccgagc     2700

aggccaagcu gcccgccacc gagaagcccg ugcugcugag caaggacauc gaggccaaga     2760

ugauggcccu ggacagagag gugcaguacc ugcugaacaa ggccaaguuc accaagccca     2820

gacccagacc caaggacaag aacggcacca gagccgagcc cccccugaac gccagcgcca     2880

gcgaccaggg cgagaaggug aucccccccg ccggccagac cgaggacgcc gagcccauca     2940

gcgagcccga gaagguggag accggcagcg agcccggcga caccgagccc cuggagcugg     3000

gcggccccgg cgccgagccc gagcagaagg agcagagcac cggccagaag agaccccuga     3060

agaacgacga gcugugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6658
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt4)

<400>  6658
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaga cccagaccca ggaccagccc auggaggagg      120

aggaggugga gaccuucgcc uuccaggccg agaucgccca gcugaugagc cugaucauca      180

acaccuucua cagcaacaag gagaucuucc ugagagagcu gaucagcaac agcagcgacg      240

cccuggacaa gaucagauac gagagccuga ccgaccccag caagcuggac agcggcaagg      300

agcugcacau caaccugauc cccaacaagc aggacagaac ccugaccauc guggacaccg      360

gcaucggcau gaccaaggcc gaccugauca acaaccuggg caccaucgcc aagagcggca      420

ccaaggccuu cauggaggcc cugcaggccg gcgccgacau cagcaugauc ggccaguucg      480

gcgugggcuu cuacagcgcc uaccuggugg ccgagaaggu gaccgugauc accaagcaca      540

acgacgacga gcaguacgcc ugggagagca gcgccggcgg cagcuucacc gugagaaccg      600

acaccggcga gcccaugggc agaggcacca aggugauccu gcaccugaag gaggaccaga      660

ccgaguaccu ggaggagaga agaaucaagg agaucgugaa gaagcacagc caguucaucg      720

gcuaccccau cacccuguuc guggagaagg agagagacaa ggaggugagc gacgacgagg      780

ccgaggagaa ggaggacaag gaggaggaga aggagaagga ggagaaggag agcgaggaca      840

agcccgagau cgaggacgug ggcagcgacg aggaggagga gaagaaggac ggcgacaaga      900

agaagaagaa gaagaucaag gagaaguaca ucgaccagga ggagcugaac aagaccaagc      960

ccaucuggac cagaaacccc gacgacauca ccaacgagga guacggcgag uucuacaaga     1020

gccugaccaa cgacugggag gaccaccugg ccgugaagca cuucagcgug gagggccagc     1080

uggaguucag agcccugcug uucgugccca gaagagcccc cuucgaccug uucgagaaca     1140

gaaagaagaa gaacaacauc aagcuguacg ugagaagagu guucaucaug gacaacugcg     1200

aggagcugau ccccgaguac cugaacuuca ucagaggcgu gguggacagc gaggaccugc     1260

cccugaacau cagcagagag augcugcagc agagcaagau ccugaaggug aucagaaaga     1320

accuggugaa gaagugccug gagcuguuca ccgagcuggc cgaggacaag gagaacuaca     1380

agaaguucua cgagcaguuc agcaagaaca ucaagcuggg cauccacgag gacagccaga     1440

acagaaagaa gcugagcgag cugcugagau acuacaccag cgccagcggc gacgagaugg     1500

ugagccugaa ggacuacugc accagaauga aggagaacca gaagcacauc uacuacauca     1560

ccggcgagac caaggaccag guggccaaca gcgccuucgu ggagagacug agaaagcacg     1620

gccuggaggu gaucuacaug aucgagccca ucgacgagua cugcgugcag cagcugaagg     1680

aguucgaggg caagacccug gugagcguga ccaaggaggg ccuggagcug cccgaggacg     1740

aggaggagaa gaagaagcag gaggagaaga agaccaaguu cgagaaccug ugcaagauca     1800

ugaaggacau ccuggagaag aagguggaga aggugguggu gagcaacaga cuggugacca     1860

gccccugcug caucgugacc agcaccuacg gcuggaccgc caacauggag agaaucauga     1920

aggcccaggc ccugagagac aacagcacca ugggcuacau ggccgccaag aagcaccugg     1980

agaucaaccc cgaccacagc aucaucgaga cccugagaca gaaggccgag gccgacaaga     2040

acgacaagag cgugaaggac cuggugaucc ugcuguacga gaccgcccug cugagcagcg     2100

gcuucagccu ggaggacccc cagacccacg ccaacagaau cuacagaaug aucaagcugg     2160

gccugggcau cgacgaggac gaccccaccg ccgacgacac cagcgccgcc gugaccgagg     2220

agaugccccc ccuggagggc gacgacgaca ccagcagaau ggaggaggug gacugaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  6659
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt4)

<400>  6659
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcagca agcuggacag cggcaagggc cugcacauca      120

accuggugcc caacaagcag aaccagaccc ugaccaucgu ggacaccaga aucggcauga      180

ccaagaccga ccugaucaac aaccugggca ccgugaccaa gagcggcacc aaggccuuca      240

uggaggcccu gcaggccgac gccgacauca gcaugaucgg ccacuucggc gugggcuucu      300

acagcgccua ccugguggcc aagaagguga ccgugaucag caagcacaac aacgacgagc      360

aguacaccug ggagagcagc gccggcggca gcuucaccgu gagaaccgac gagugaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  6660
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt4)

<400>  6660
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggagg ugcaccacgg cgaggaggag guggagaccu      120

ucgccuucca ggccgagauc gcccagcuga ugagccugau caucaacacc uucuacagca      180

acaaggagau cuuccugaga gagcugauca gcaacgccag cgacgcccug gacaagauca      240

gauacgagag ccugaccgac cccagcaagc uggacagcgg caaggagcug aagaucgaca      300

ucauccccaa cccccaggag agaacccuga cccuggugga caccggcauc ggcaugacca      360

aggccgaccu gaucaacaac cugggcacca ucgccaagag cggcaccaag gccuucaugg      420

aggcccugca ggccggcgcc gacaucagca ugaucggcca guucggcgug ggcuucuaca      480

gcgccuaccu gguggccgag aagguggugg ugaucaccaa gcacaacgac gacgagcagu      540

acgccuggga gagcagcgcc ggcggcagcu ucaccgugag agccgaccac ggcgagccca      600

ucggcagagg caccaaggug auccugcacc ugaaggagga ccagaccgag uaccuggagg      660

agagaagagu gaaggaggug gugaagaagc acagccaguu caucggcuac cccaucaccc      720

uguaccugga gaaggagaga gagaaggaga ucagcgacga cgaggccgag gaggagaagg      780

gcgagaagga ggaggaggac aaggacgacg aggagaagcc caagaucgag gacgugggca      840

gcgacgagga ggacgacagc ggcaaggaca agaagaagaa gaccaagaag aucaaggaga      900

aguacaucga ccaggaggag cugaacaaga ccaagcccau cuggaccaga aaccccgacg      960

acaucaccca ggaggaguac ggcgaguucu acaagagccu gaccaacgac ugggaggacc     1020

accuggccgu gaagcacuuc agcguggagg gccagcugga guucagagcc cugcuguuca     1080

uccccagaag agcccccuuc gaccuguucg agaacaagaa gaagaagaac aacaucaagc     1140

uguacgugag aagaguguuc aucauggaca gcugcgacga gcugaucccc gaguaccuga     1200

acuucaucag aggcguggug gacagcgagg accugccccu gaacaucagc agagagaugc     1260

ugcagcagag caagauccug aaggugauca gaaagaacau cgugaagaag ugccuggagc     1320

uguucagcga gcuggccgag gacaaggaga acuacaagaa guucuacgag gccuucagca     1380

agaaccugaa gcugggcauc cacgaggaca gcaccaacag aagaagacug agcgagcugc     1440

ugagauacca caccagccag agcggcgacg agaugaccag ccugagcgag uacgugagca     1500

gaaugaagga gacccagaag agcaucuacu acaucaccgg cgagagcaag gagcaggugg     1560

ccaacagcgc cuucguggag agagugagaa agagaggcuu cgagguggug uacaugaccg     1620

agcccaucga cgaguacugc gugcagcagc ugaaggaguu cgacggcaag agccugguga     1680

gcgugaccaa ggagggccug gagcugcccg aggacgagga ggagaagaag aagauggagg     1740

agagcaaggc caaguucgag aaccugugca agcugaugaa ggagauccug gacaagaagg     1800

uggagaaggu gaccaucagc aacagacugg ugagcagccc cugcugcauc gugaccagca     1860

ccuacggcug gaccgccaac auggagagaa ucaugaaggc ccaggcccug agagacaaca     1920

gcaccauggg cuacaugaug gccaagaagc accuggagau caaccccgac caccccaucg     1980

uggagacccu gagacagaag gccgaggccg acaagaacga caaggccgug aaggaccugg     2040

uggugcugcu guucgagacc gcccugcuga gcagcggcuu cagccuggag gacccccaga     2100

cccacagcaa cagaaucuac agaaugauca agcugggccu gggcaucgac gaggacgagg     2160

uggccgccga ggagcccaac gccgccgugc ccgacgagau ccccccccug gagggcgacg     2220

aggacgccag cagaauggag gagguggacu gaggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  6661
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt4)

<400>  6661
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agagcccugu gggugcuggg ccugugcugc gugcugcuga      120

ccuucggcag cgugagagcc gacgacgagg uggacgugga cggcaccgug gaggaggacc      180

ugggcaagag cagagagggc agcagaaccg acgacgaggu ggugcagaga gaggaggagg      240

ccauccagcu ggacggccug aacgccagcc agaucagaga gcugagagag aagagcgaga      300

aguucgccuu ccaggccgag gugaacagaa ugaugaagcu gaucaucaac agccuguaca      360

agaacaagga gaucuuccug agagagcuga ucagcaacgc cagcgacgcc cuggacaaga      420

ucagacugau cagccugacc gacgagaacg cccugagcgg caacgaggag cugaccguga      480

agaucaagug cgacaaggag aagaaccugc ugcacgugac cgacaccggc gugggcauga      540

ccagagagga gcuggugaag aaccugggca ccaucgccaa gagcggcacc agcgaguucc      600

ugaacaagau gaccgaggcc caggaggacg gccagagcac cagcgagcug aucggccagu      660

ucggcguggg cuucuacagc gccuuccugg uggccgacaa ggugaucgug accagcaagc      720

acaacaacga cacccagcac aucugggaga gcgacagcaa cgaguucagc gugaucgccg      780

accccagagg caacacccug ggcagaggca ccaccaucac ccuggugcug aaggaggagg      840

ccagcgacua ccuggagcug gacaccauca agaaccuggu gaagaaguac agccaguuca      900

ucaacuuccc caucuacgug uggagcagca agaccgagac cguggaggag cccauggagg      960

aggaggaggc cgccaaggag gagaaggagg agagcgacga cgaggccgcc guggaggagg     1020

aggaggagga gaagaagccc aagaccaaga agguggagaa gaccgugugg gacugggagc     1080

ugaugaacga caucaagccc aucuggcaga gacccagcaa ggagguggag gaggacgagu     1140

acaaggccuu cuacaagagc uucagcaagg agagcgacga ccccauggcc uacauccacu     1200

ucaccgccga gggcgaggug accuucaaga gcauccuguu cgugcccacc agcgccccca     1260

gaggccuguu cgacgaguac ggcagcaaga agagcgacua caucaagcug uacgugagaa     1320

gaguguucau caccgacgac uuccacgaca ugaugcccaa guaccugaac uucgugaagg     1380

gcguggugga cagcgacgac cugccccuga acgugagcag agagacccug cagcagcaca     1440

agcugcugaa ggugaucaga aagaagcugg ugagaaagac ccuggacaug aucaagaaga     1500

ucgccgacga caaguacaac gacaccuucu ggaaggaguu cggcaccaac aucaagcugg     1560

gcgugaucga ggaccacagc aacagaacca gacuggccaa gcugcugaga uuccagagca     1620

gccaccaccc caccgacauc accagccugg accaguacgu ggagagaaug aaggagaagc     1680

aggacaagau cuacuucaug gccggcagca gcagaaagga ggccgagagc agccccuucg     1740

uggagagacu gcugaagaag ggcuacgagg ugaucuaccu gaccgagccc guggacgagu     1800

acugcaucca ggcccugccc gaguucgacg gcaagagauu ccagaacgug gccaaggagg     1860

gcgugaaguu cgacgagagc gagaagacca aggagagcag agaggccgug gagaaggagu     1920

ucgagccccu gcugaacugg augaaggaca aggcccugaa ggacaagauc gagaaggccg     1980

uggugagcca gagacugacc gagagccccu gcgcccuggu ggccagccag uacggcugga     2040

gcggcaacau ggagagaauc augaaggccc aggccuacca gaccggcaag gacaucagca     2100

ccaacuacua cgccagccag aagaagaccu ucgagaucaa ccccagacac ccccugauca     2160

gagacaugcu gagaagaauc aaggaggacg aggacgacaa gaccgugcug gaccuggccg     2220

uggugcuguu cgagaccgcc acccugagaa gcggcuaccu gcugcccgac accaaggccu     2280

acggcgacag aaucgagaga augcugagac ugagccugaa caucgacccc gacgccaagg     2340

uggaggagga gcccgaggag gagcccgagg agaccgccga ggacaccacc gaggacaccg     2400

agcaggacga ggacgaggag auggacgugg gcaccgacga ggaggaggag accgccaagg     2460

agagcaccgc cgagaaggac gagcugugag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  6662
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt4)

<400>  6662
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagagagc ugagagcccu gcugcugugg ggcagaagac      120

ugagaccccu gcugagagcc cccgcccugg ccgccgugcc cggcggcaag cccauccugu      180

gccccagaag aaccaccgcc cagcugggcc ccagaagaaa ccccgccugg agccugcagg      240

ccggcagacu guucagcacc cagaccgccg aggacaagga ggagccccug cacagcauca      300

ucagcagcac cgagagcgug cagggcagca ccagcaagca cgaguuccag gccgagacca      360

agaagcugcu ggacaucgug gccagaagcc uguacagcga gaaggaggug uucaucagag      420

agcugaucag caacgccagc gacgcccugg agaagcugag acacaagcug gugagcgacg      480

gccaggcccu gcccgagaug gagauccacc ugcagaccaa cgccgagaag ggcaccauca      540

ccauccagga caccggcauc ggcaugaccc aggaggagcu ggugagcaac cugggcacca      600

ucgccagaag cggcagcaag gccuuccugg acgcccugca gaaccaggcc gaggccagca      660

gcaagaucau cggccaguuc ggcgugggcu ucuacagcgc cuucauggug gccgacagag      720

uggaggugua cagcagaagc gccgcccccg gcagccuggg cuaccagugg cugagcgacg      780

gcagcggcgu guucgagauc gccgaggcca gcggcgugag aaccggcacc aagaucauca      840

uccaccugaa gagcgacugc aaggaguuca gcagcgaggc cagagugaga gacgugguga      900

ccaaguacag caacuucgug agcuuccccc uguaccugaa cggcagaaga augaacaccc      960

ugcaggccau cuggaugaug gaccccaagg acgugagaga guggcagcac gaggaguucu     1020

acagauacgu ggcccaggcc cacgacaagc ccagauacac ccugcacuac aagaccgacg     1080

ccccccugaa caucagaagc aucuucuacg ugcccgacau gaagcccagc auguucgacg     1140

ugagcagaga gcugggcagc agcguggccc uguacagcag aaaggugcug auccagacca     1200

aggccaccga cauccugccc aaguggcuga gauucaucag aggcguggug gacagcgagg     1260

acaucccccu gaaccugagc agagagcugc ugcaggagag cgcccugauc agaaagcuga     1320

gagacgugcu gcagcagaga cugaucaagu ucuucaucga ccagagcaag aaggacgccg     1380

agaaguacgc caaguucuuc gaggacuacg gccuguucau gagagagggc aucgugaccg     1440

ccaccgagca ggaggugaag gaggacaucg ccaagcugcu gagauacgag agcagcgccc     1500

ugcccagcgg ccagcugacc agccugagcg aguacgccag cagaaugaga gccggcacca     1560

gaaacaucua cuaccugugc gcccccaaca gacaccuggc cgagcacagc cccuacuacg     1620

aggccaugaa gaagaaggac accgaggugc uguucugcuu cgagcaguuc gacgagcuga     1680

cccugcugca ccugagagag uucgacaaga agaagcugau cagcguggag accgacaucg     1740

ugguggacca cuacaaggag gagaaguucg aggacagaag ccccgccgcc gagugccuga     1800

gcgagaagga gaccgaggag cugauggccu ggaugagaaa cgugcugggc agcagaguga     1860

ccaacgugaa ggugacccug agacuggaca cccaccccgc cauggugacc gugcuggaga     1920

ugggcgccgc cagacacuuc cugagaaugc agcagcuggc caagacccag gaggagagag     1980

cccagcugcu gcagcccacc cuggagauca accccagaca cgcccugauc aagaagcuga     2040

accagcugag agccagcgag cccggccugg cccagcugcu gguggaccag aucuacgaga     2100

acgccaugau cgccgccggc cugguggacg accccagagc cauggugggc agacugaacg     2160

agcugcuggu gaaggcccug gagagacacu gaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  6663
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt4)

<400>  6663
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagauca gcagccugcc cacccagcug uucaagugcu      120

gcuucugcga cuuccugaag gugaagaugc acaccaugag cagcagccac cuguucuacc      180

uggcccugug ccugcugacc uucaccagca gcgccaccgc cggccccgag acccugugcg      240

gcgccgagcu gguggacgcc cugcaguucg ugugcggcga cagaggcuuc uacuucaaca      300

agcccaccgg cuacggcagc agcagcagaa gagcccccca gaccggcauc guggacgagu      360

gcugcuucag aagcugcgac cugagaagac uggagaugua cugcgccccc cugaagcccg      420

ccaagagcgc cagaagcgug agagcccaga gacacaccga caugcccaag acccagaagg      480

aggugcaccu gaagaacgcc agcagaggca gcgccggcaa caagaacuac agaaugugag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  6664
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt4)

<400>  6664
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca ugggcaagag caugcuggug cugcugaccu      120

uccuggccuu cgccagcugc ugcaucgccg ccuacagacc cagcgagacc cugugcggcg      180

gcgagcuggu ggacacccug caguucgugu gcggcgacag aggcuucuac uucagcagac      240

ccgccagcag agugagcaga agaagcagag gcaucgugga ggagugcugc uucagaagcu      300

gcgaccuggc ccugcuggag accuacugcg ccacccccgc caagagcgag agagacguga      360

gcaccccccc caccgugcug cccgacaacu uccccagaua ccccgugggc aaguucuucc      420

aguacgacac cuggaagcag agcacccaga gacugagaag aggccugccc gcccugcuga      480

gagccagaag aggccacgug cuggccaagg agcuggaggc cuucagagag gccaagagac      540

acagaccccu gaucgcccug cccacccagg accccgccca cggcggcgcc ccccccgaga      600

uggccagcaa cagaaaguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  6665
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt4)

<400>  6665
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagcuuca gcaccagcgc cuucggcccc guggccuuca      120

gccugggccu gcugcuggug cugcccgccg ccuuccccgc ccccgugccc cccggcgagg      180

acagcaagga cguggccgcc ccccacagac agccccugac cagcagcgag agaaucgaca      240

agcagaucag auacauccug gacggcauca gcgcccugag aaaggagacc ugcaacaaga      300

gcaacaugug cgagagcagc aaggaggccc uggccgagaa caaccugaac cugcccaaga      360

uggccgagaa ggacggcugc uuccagagcg gcuucaacga ggagaccugc cuggugaaga      420

ucaucaccgg ccugcuggag uucgaggugu accuggagua ccugcagaac agauucgaga      480

gcagcgagga gcaggccaga gccgugcaga ugagcaccaa ggugcugauc caguuccugc      540

agaagaaggc caagaaccug gacgccauca ccacccccga ccccaccacc aacgccagcc      600

ugcugaccaa gcugcaggcc cagaaccagu ggcugcagga caugaccacc caccugaucc      660

ugagaagcuu caaggaguuc cugcagagca gccugagagc ccugagacag augugaggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  6666
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt4)

<400>  6666
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcugu ggcugagagg cuuccugcug gccagcugcu      120

ggaucaucgu gagaagcagc cccacccccg gcagcgaggg ccacagcgcc gcccccgacu      180

gccccagcug cgcccuggcc gcccugccca aggacgugcc caacagccag cccgagaugg      240

uggaggccgu gaagaagcac auccugaaca ugcugcaccu gaagaagaga cccgacguga      300

cccagcccgu gcccaaggcc gcccugcuga acgccaucag aaagcugcac gugggcaagg      360

ugggcgagaa cggcuacgug gagaucgagg acgacaucgg cagaagagcc gagaugaacg      420

agcugaugga gcagaccagc gagaucauca ccuucgccga gagcggcacc gccagaaaga      480

cccugcacuu cgagaucagc aaggagggca gcgaccugag cgugguggag agagccgagg      540

uguggcuguu ccugaaggug cccaaggcca acagaaccag aaccaaggug accaucagac      600

uguuccagca gcagaagcac ccccagggca gccuggacac cggcgaggag gccgaggagg      660

ugggccugaa gggcgagaga agcgagcugc ugcugagcga gaagguggug gacgccagaa      720

agagcaccug gcacguguuc cccgugagca gcagcaucca gagacugcug gaccagggca      780

agagcagccu ggacgugaga aucgccugcg agcagugcca ggagagcggc gccagccugg      840

ugcugcuggg caagaagaag aagaaggagg aggagggcga gggcaagaag aagggcggcg      900

gcgagggcgg cgccggcgcc gacgaggaga aggagcagag ccacagaccc uuccugaugc      960

ugcaggccag acagagcgag gaccaccccc acagaagaag aagaagaggc cuggagugcg     1020

acggcaaggu gaacaucugc ugcaagaagc aguucuucgu gagcuucaag gacaucggcu     1080

ggaacgacug gaucaucgcc cccagcggcu accacgccaa cuacugcgag ggcgagugcc     1140

ccagccacau cgccggcacc agcggcagca gccugagcuu ccacagcacc gugaucaacc     1200

acuacagaau gagaggccac agccccuucg ccaaccugaa gagcugcugc gugcccacca     1260

agcugagacc caugagcaug cuguacuacg acgacggcca gaacaucauc aagaaggaca     1320

uccagaacau gaucguggag gagugcggcu gcagcugagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  6667
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt4)

<400>  6667
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccugc ccggcagagc ccugggcgcc gccugccugc      120

ugcugcuggc cgccggcugg cugggccccg aggccugggg cagccccacc ccccccccca      180

cccccgccgc cccccccccc cccccccccc ccggcagccc cggcggcagc caggacaccu      240

gcaccagcug cggcggcuuc agaagacccg aggagcuggg cagaguggac ggcgacuucc      300

uggaggccgu gaagagacac auccugagca gacugcagau gagaggcaga cccaacauca      360

cccacgccgu gcccaaggcc gccaugguga ccgcccugag aaagcugcac gccggcaagg      420

ugagagagga cggcagagug gagauccccc accuggacgg ccacgccagc cccggcgccg      480

acggccagga gagagugagc gagaucauca gcuucgccga gaccgacggc cuggccagca      540

gcagagugag acuguacuuc uucaucagca acgagggcaa ccagaaccug uucguggugc      600

aggccagccu guggcuguac cugaagcugc ugcccuacgu gcuggagaag ggcagcagaa      660

gaaaggugag agugaaggug uacuuccagg agcagggcca cggcgacaga uggaacaugg      720

uggagaagag aguggaccug aagagaagcg gcuggcacac cuucccccug accgaggcca      780

uccaggcccu guucgagaga ggcgagagaa gacugaaccu ggacgugcag ugcgacagcu      840

gccaggagcu ggccguggug cccguguucg uggaccccgg cgaggagagc cacagacccu      900

ucgugguggu gcaggccaga cugggcgaca gcagacacag aaucagaaag agaggccugg      960

agugcgacgg cagaaccaac cugugcugca gacagcaguu cuucaucgac uucagacuga     1020

ucggcuggaa cgacuggauc aucgccccca ccggcuacua cggcaacuac ugcgagggca     1080

gcugccccgc cuaccuggcc ggcgugcccg gcagcgccag cagcuuccac accgccgugg     1140

ugaaccagua cagaaugaga ggccugaacc ccggcaccgu gaacagcugc ugcaucccca     1200

ccaagcugag caccaugagc augcuguacu ucgacgacga guacaacauc gugaagagag     1260

acgugcccaa caugaucgug gaggagugcg gcugcgccug aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  6668
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt4)

<400>  6668
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagag ugcugcugcu gaccgcccug acccugugcc      120

acggcuucaa ccuggacacc gagaacgcca ugaccuucca ggagaacgcc agaggcuucg      180

gccagagcgu ggugcagcug cagggcagca gagugguggu gggcgccccc caggagaucg      240

uggccgccaa ccagagaggc agccuguacc agugcgacua cagcaccggc agcugcgagc      300

ccaucagacu gcaggugccc guggaggccg ugaacaugag ccugggccug agccuggccg      360

ccaccaccag ccccccccag cugcuggccu gcggccccac cgugcaccag accugcagcg      420

agaacaccua cgugaagggc cugugcuucc uguucggcag caaccugaga cagcagcccc      480

agaaguuccc cgaggcccug agaggcugcc cccaggagga cagcgacauc gccuuccuga      540

ucgacggcag cggcagcauc aucccccacg acuucagaag aaugaaggag uucgugagca      600

ccgugaugga gcagcugaag aagagcaaga cccuguucag ccugaugcag uacagcgagg      660

aguucagaau ccacuucacc uucaaggagu uccagaacaa ccccaacccc agaagccugg      720

ugaagcccau cacccagcug cugggcagaa cccacaccgc caccggcauc agaaaggugg      780

ugagagagcu guucaacauc accaacggcg ccagaaagaa cgccuucaag auccuggugg      840

ugaucaccga cggcgagaag uucggcgacc cccugggcua cgaggacgug auccccgagg      900

ccgacagaga gggcgugauc agauacguga ucggcguggg cgacgccuuc agaagcgaga      960

agagcagaca ggagcugaac accaucgcca gcaagccccc cagagaccac guguuccagg     1020

ugaacaacuu cgaggcccug aagaccaucc agaaccagcu gagagagaag aucuucgcca     1080

ucgagggcac ccagaccggc agcagcagca gcuucgagca cgagaugagc caggagggcu     1140

ucagcgccgc caucaccagc aacggccccc ugcugagcac cgugggcagc uacgacuggg     1200

ccggcggcgu guuccuguac accagcaagg agaagagcac cuucaucaac augaccagag     1260

uggacagcga caugaacgac gccuaccugg gcuacgccgc cgccaucauc cugagaaaca     1320

gagugcagag ccuggugcug ggcgccccca gauaccagca caucggccug guggccaugu     1380

ucagacagaa caccggcaug ugggagagca acgccaacgu gaagggcacc cagaucggcg     1440

ccuacuucgg cgccagccug ugcagcgugg acguggacag caacggcagc accgaccugg     1500

ugcugaucgg cgccccccac uacuacgagc agaccagagg cggccaggug agcgugugcc     1560

cccugcccag aggcagagcc agauggcagu gcgacgccgu gcuguacggc gagcagggcc     1620

agcccugggg cagauucggc gccgcccuga ccgugcuggg cgacgugaac ggcgacaagc     1680

ugaccgacgu ggccaucggc gcccccggcg aggaggacaa cagaggcgcc guguaccugu     1740

uccacggcac cagcggcagc ggcaucagcc ccagccacag ccagagaauc gccggcagca     1800

agcugagccc cagacugcag uacuucggcc agagccugag cggcggccag gaccugacca     1860

uggacggccu gguggaccug accgugggcg cccagggcca cgugcugcug cugagaagcc     1920

agcccgugcu gagagugaag gccaucaugg aguucaaccc cagagaggug gccagaaacg     1980

uguucgagug caacgaccag guggugaagg gcaaggaggc cggcgaggug agagugugcc     2040

ugcacgugca gaagagcacc agagacagac ugagagaggg ccagauccag agcgugguga     2100

ccuacgaccu ggcccuggac agcggcagac cccacagcag agccguguuc aacgagacca     2160

agaacagcac cagaagacag acccaggugc ugggccugac ccagaccugc gagacccuga     2220

agcugcagcu gcccaacugc aucgaggacc ccgugagccc caucgugcug agacugaacu     2280

ucagccuggu gggcaccccc cugagcgccu ucggcaaccu gagacccgug cuggccgagg     2340

acgcccagag acuguucacc gcccuguucc ccuucgagaa gaacugcggc aacgacaaca     2400

ucugccagga cgaccugagc aucaccuuca gcuucaugag ccuggacugc cugguggugg     2460

gcggccccag agaguucaac gugaccguga ccgugagaaa cgacggcgag gacagcuaca     2520

gaacccaggu gaccuucuuc uucccccugg accugagcua cagaaaggug agcacccugc     2580

agaaccagag aagccagaga agcuggagac uggccugcga gagcgccagc agcaccgagg     2640

ugagcggcgc ccugaagagc accagcugca gcaucaacca ccccaucuuc cccgagaaca     2700

gcgaggugac cuucaacauc accuucgacg uggacagcaa ggccagccug ggcaacaagc     2760

ugcugcugaa ggccaacgug accagcgaga acaacaugcc cagaaccaac aagaccgagu     2820

uccagcugga gcugcccgug aaguacgccg uguacauggu ggugaccagc cacggcguga     2880

gcaccaagua ccugaacuuc accgccagcg agaacaccag cagagugaug cagcaccagu     2940

accaggugag caaccugggc cagagaagcc ugcccaucag ccugguguuc cuggugcccg     3000

ugagacugaa ccagaccgug aucugggaca gaccccaggu gaccuucagc gagaaccuga     3060

gcagcaccug ccacaccaag gagagacugc ccagccacag cgacuuccug gccgagcuga     3120

gaaaggcccc cguggugaac ugcagcaucg ccgugugcca gagaauccag ugcgacaucc     3180

ccuucuucgg cauccaggag gaguucaacg ccacccugaa gggcaaccug agcuucgacu     3240

gguacaucaa gaccagccac aaccaccugc ugaucgugag caccgccgag auccuguuca     3300

acgacagcgu guucacccug cugcccggcc agggcgccuu cgugagaagc cagaccgaga     3360

ccaaggugga gcccuucgag gugcccaacc cccugccccu gaucgugggc agcagcgugg     3420

gcggccugcu gcugcuggcc cugaucaccg ccgcccugua caagcugggc uucuucaaga     3480

gacaguacaa ggacaugaug agcgagggcg gcccccccgg cgccgagccc cagugaggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  6669
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt4)

<400>  6669
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucagccuga agacccugcc cuuccugcug cugcugcacg      120

ugcagaucag caaggccuuc cccgugagca gcaaggagaa gaacaccaag accgugcagg      180

acuaccugga gaaguucuac cagcugccca gcaaccagua ccagagcacc agaaagaacg      240

gcaccaacgu gaucguggag aagcugaagg agaugcagag auucuucggc cugaacguga      300

ccggcaagcc caacgaggag acccuggaca ugaugaagaa gcccagaugc ggcgugcccg      360

acagcggcgg cuucaugcug acccccggca accccaagug ggagagaacc aaccugaccu      420

acagaaucag aaacuacacc ccccagcuga gcgaggccga gguggagaga gccaucaagg      480

acgccuucga gcuguggagc guggccagcc cccugaucuu caccagaauc agccagggcg      540

aggccgacau caacaucgcc uucuaccaga gagaccacgg cgacaacagc cccuucgacg      600

gccccaacgg cauccuggcc cacgccuucc agcccggcca gggcaucggc ggcgacgccc      660

acuucgacgc cgaggagacc uggaccaaca ccagcgccaa cuacaaccug uuccuggugg      720

ccgcccacga guucggccac agccugggcc uggcccacag cagcgacccc ggcgcccuga      780

uguaccccaa cuacgccuuc agagagacca gcaacuacag ccugccccag gacgacaucg      840

acggcaucca ggccaucuac ggccugagca gcaaccccau ccagcccacc ggccccagca      900

cccccaagcc cugcgacccc agccugaccu ucgacgccau caccacccug agaggcgaga      960

uccuguucuu caaggacaga uacuucugga gaagacaccc ccagcugcag agaguggaga     1020

ugaacuucau cagccuguuc uggcccagcc ugcccaccgg cauccaggcc gccuacgagg     1080

acuucgacag agaccugauc uuccuguuca agggcaacca guacugggcc cugagcggcu     1140

acgacauccu gcagggcuac cccaaggaca ucagcaacua cggcuucccc agcagcgugc     1200

aggccaucga cgccgccgug uucuacagaa gcaagaccua cuucuucgug aacgaccagu     1260

ucuggagaua cgacaaccag agacaguuca uggagcccgg cuaccccaag agcaucagcg     1320

gcgccuuccc cggcaucgag agcaaggugg acgccguguu ccagcaggag cacuucuucc     1380

acguguucag cggccccaga uacuacgccu ucgaccugau cgcccagaga gugaccagag     1440

uggccagagg caacaagugg cugaacugca gauacggcug aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  6670
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt4)

<400>  6670
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguggc agccccuggu gcuggugcug cuggugcugg      120

gcugcugcuu cgccgccccc agacagagac agagcacccu ggugcuguuc cccggcgacc      180

ugagaaccaa ccugaccgac agacagcugg ccgaggagua ccuguacaga uacggcuaca      240

ccagaguggc cgagaugaga ggcgagagca agagccuggg ccccgcccug cugcugcugc      300

agaagcagcu gagccugccc gagaccggcg agcuggacag cgccacccug aaggccauga      360

gaacccccag augcggcgug cccgaccugg gcagauucca gaccuucgag ggcgaccuga      420

aguggcacca ccacaacauc accuacugga uccagaacua cagcgaggac cugcccagag      480

ccgugaucga cgacgccuuc gccagagccu ucgcccugug gagcgccgug accccccuga      540

ccuucaccag aguguacagc agagacgccg acaucgugau ccaguucggc guggccgagc      600

acggcgacgg cuaccccuuc gacggcaagg acggccugcu ggcccacgcc uucccccccg      660

gccccggcau ccagggcgac gcccacuucg acgacgacga gcuguggagc cugggcaagg      720

gcgugguggu gcccaccaga uucggcaacg ccgacggcgc cgccugccac uuccccuuca      780

ucuucgaggg cagaagcuac agcgccugca ccaccgacgg cagaagcgac ggccugcccu      840

ggugcagcac caccgccaac uacgacaccg acgacagauu cggcuucugc cccagcgaga      900

gacuguacac ccaggacggc aacgccgacg gcaagcccug ccaguucccc uucaucuucc      960

agggccagag cuacagcgcc ugcaccaccg acggcagaag cgacggcuac agauggugcg     1020

ccaccaccgc caacuacgac agagacaagc uguucggcuu cugccccacc agagccgaca     1080

gcaccgugau gggcggcaac agcgccggcg agcugugcgu guuccccuuc accuuccugg     1140

gcaaggagua cagcaccugc accagcgagg gcagaggcga cggcagacug uggugcgcca     1200

ccaccagcaa cuucgacagc gacaagaagu ggggcuucug ccccgaccag ggcuacagcc     1260

uguuccuggu ggccgcccac gaguucggcc acgcccuggg ccuggaccac agcagcgugc     1320

ccgaggcccu gauguacccc auguacagau ucaccgaggg ccccccccug cacaaggacg     1380

acgugaacgg caucagacac cuguacggcc ccagacccga gcccgagccc agacccccca     1440

ccaccaccac cccccagccc accgcccccc ccaccgugug ccccaccggc ccccccaccg     1500

ugcaccccag cgagagaccc accgccggcc ccaccggccc ccccagcgcc ggccccaccg     1560

gcccccccac cgccggcccc agcaccgcca ccaccgugcc ccugagcccc guggacgacg     1620

ccugcaacgu gaacaucuuc gacgccaucg ccgagaucgg caaccagcug uaccuguuca     1680

aggacggcaa guacuggaga uucagcgagg gcagaggcag cagaccccag ggccccuucc     1740

ugaucgccga caaguggccc gcccugccca gaaagcugga cagcguguuc gaggagagac     1800

ugagcaagaa gcuguucuuc uucagcggca gacaggugug gguguacacc ggcgccagcg     1860

ugcugggccc cagaagacug gacaagcugg gccugggcgc cgacguggcc caggugaccg     1920

gcgcccugag aagcggcaga ggcaagaugc ugcuguucag cggcagaaga cuguggagau     1980

ucgacgugaa ggcccagaug guggacccca gaagcgccag cgagguggac agaauguucc     2040

ccggcgugcc ccuggacacc cacgacgugu uccaguacag agagaaggcc uacuucugcc     2100

aggacagauu cuacuggaga gugagcagca gaagcgagcu gaaccaggug gaccaggugg     2160

gcuacgugac cuacgacauc cugcagugcc ccgaggacug aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  6671
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt4)

<400>  6671
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg ugcuggccgc cuuccuguuc cugagcugga      120

cccacugcag agcccugccc cugcccagcg gcggcgacga ggacgaccug agcgaggagg      180

accugcaguu cgccgagaga uaccugagaa gcuacuacca ccccaccaac cuggccggca      240

uccugaagga gaacgccgcc agcagcauga ccgagagacu gagagagaug cagagcuucu      300

ucggccugga ggugaccggc aagcuggacg acaacacccu ggacgugaug aagaagccca      360

gaugcggcgu gcccgacgug ggcgaguaca acguguuccc cagaacccug aaguggagca      420

agaugaaccu gaccuacaga aucgugaacu acacccccga caugacccac agcgaggugg      480

agaaggccuu caagaaggcc uucaaggugu ggagcgacgu gaccccccug aacuucacca      540

gacugcacga cggcaucgcc gacaucauga ucagcuucgg caucaaggag cacggcgacu      600

ucuaccccuu cgacggcccc agcggccugc uggcccacgc cuuccccccc ggccccaacu      660

acggcggcga cgcccacuuc gacgacgacg agaccuggac cagcagcagc aagggcuaca      720

accuguuccu gguggccgcc cacgaguucg gccacagccu gggccuggac cacagcaagg      780

accccggcgc ccugauguuc cccaucuaca ccuacaccgg caagagccac uucaugcugc      840

ccgacgacga cgugcagggc auccagagcc uguacggccc cggcgacgag gaccccaacc      900

ccaagcaccc caagaccccc gacaagugcg accccagccu gagccuggac gccaucacca      960

gccugagagg cgagaccaug aucuucaagg acagauucuu cuggagacug cacccccagc     1020

agguggacgc cgagcuguuc cugaccaaga gcuucuggcc cgagcugccc aacagaaucg     1080

acgccgccua cgagcacccc agccacgacc ugaucuucau cuucagaggc agaaaguucu     1140

gggcccugaa cggcuacgac auccuggagg gcuaccccaa gaagaucagc gagcugggcc     1200

ugcccaagga ggugaagaag aucagcgccg ccgugcacuu cgaggacacc ggcaagaccc     1260

ugcuguucag cggcaaccag guguggagau acgacgacac caaccacauc auggacaagg     1320

acuaccccag acugaucgag gaggacuucc ccggcaucgg cgacaaggug gacgccgugu     1380

acgagaagaa cggcuacauc uacuucuuca acggccccau ccaguucgag uacagcaucu     1440

ggagcaacag aaucgugaga gugaugcccg ccaacagcau ccuguggugc ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6672
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt4)

<400>  6672
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acaccaccga ggacuacgac accaccaccg      120

aguucgacua cggcgacgcc acccccugcc agaaggugaa cgagagagcc uucggcgccc      180

agcugcugcc cccccuguac agccuggugu ucgugaucgg ccuggugggc aacauccugg      240

uggugcuggu gcuggugcag uacaagagac ugaagaacau gaccagcauc uaccugcuga      300

accuggccau cagcgaccug cuguuccugu ucacccugcc cuucuggauc gacuacaagc      360

ugaaggacga cuggguguuc ggcgacgcca ugugcaagau ccugagcggc uucuacuaca      420

ccggccugua cagcgagauc uucuucauca uccugcugac caucgacaga uaccuggcca      480

ucgugcacgc cguguucgcc cugagagcca gaaccgugac cuucggcgug aucaccagca      540

ucaucaucug ggcccuggcc auccuggcca gcaugcccgg ccuguacuuc agcaagaccc      600

agugggaguu cacccaccac accugcagcc ugcacuuccc ccacgagagc cugagagagu      660

ggaagcuguu ccaggcccug aagcugaacc uguucggccu ggugcugccc cugcugguga      720

ugaucaucug cuacaccggc aucaucaaga uccugcugag aagacccaac gagaagaaga      780

gcaaggccgu gagacugauc uucgugauca ugaucaucuu cuuccuguuc uggacccccu      840

acaaccugac cauccugauc agcguguucc aggacuuccu guucacccac gagugcgagc      900

agagcagaca ccuggaccug gccgugcagg ugaccgaggu gaucgccuac acccacugcu      960

gcgugaaccc cgugaucuac gccuucgugg gcgagagauu cagaaaguac cugagacagc     1020

uguuccacag aagaguggcc gugcaccugg ugaaguggcu gcccuuccug agcguggaca     1080

gacuggagag agugagcagc accagcccca gcaccggcga gcacgagcug agcgccggcu     1140

ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  6673
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt4)

<400>  6673
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agaacccugg ccugccugcu gcugcugggc ugcggcuacc      120

uggcccacgu gcuggccgag gaggccgaga uccccagaga ggugaucgag agacuggcca      180

gaagccagau ccacagcauc agagaccugc agagacugcu ggagaucgac agcgugggca      240

gcgaggacag ccuggacacc agccugagag cccacggcgu gcacgccacc aagcacgugc      300

ccgagaagag accccugccc aucagaagaa agagaagcau cgaggaggcc gugcccgccg      360

ugugcaagac cagaaccgug aucuacgaga uccccagaag ccagguggac cccaccagcg      420

ccaacuuccu gaucuggccc cccugcgugg aggugaagag augcaccggc ugcugcaaca      480

ccagcagcgu gaagugccag cccagcagag ugcaccacag aagcgugaag guggccaagg      540

uggaguacgu gagaaagaag cccaagcuga aggaggugca ggugagacug gaggagcacc      600

uggagugcgc cugcgccacc accagccuga accccgacua cagagaggag gacaccggca      660

gacccagaga gagcggcaag aagagaaaga gaaagagacu gaagcccacc ugaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  6674
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt4)

<400>  6674
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagaugcu gggcccuguu ccugagccug ugcugcuacc      120

ugagacuggu gagcgccgag ggcgacccca uccccgagga gcuguacgag augcugagcg      180

accacagcau cagaagcuuc gacgaccugc agagacugcu gcacggcgac cccggcgagg      240

aggacggcgc cgagcuggac cugaacauga ccagaagcca cagcggcggc gagcuggaga      300

gccuggccag aggcagaaga agccugggca gccugaccau cgccgagccc gccaugaucg      360

ccgagugcaa gaccagaacc gagguguucg agaucagcag aagacugauc gacagaacca      420

acgccaacuu ccuggugugg ccccccugcg uggaggugca gagaugcagc ggcugcugca      480

acaacagaaa cgugcagugc agacccaccc aggugcagcu gagacccgug caggugagaa      540

agaucgagau cgugagaaag aagcccaucu ucaagaaggc caccgugacc cuggaggacc      600

accuggccug caagugcgag accguggccg ccgccagacc cgugaccaga agccccggcg      660

gcagccagga gcagagagcc aagacccccc agaccagagu gaccaucaga accgugagag      720

ugagaagacc ccccaagggc aagcacagaa aguucaagca cacccacgac aagaccgccc      780

ugaaggagac ccugggcgcc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  6675
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt4)

<400>  6675
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguucg gccugcugcu gcugaccagc gcccuggccg      120

gccagagaca gggcacccag gccgagagca accugagcag caaguuccag uucagcagca      180

acaaggagca gaacggcgug caggaccccc agcacgagag aaucaucacc gugagcacca      240

acggcagcau ccacagcccc agauuccccc acaccuaccc cagaaacacc gugcuggugu      300

ggagacuggu ggccguggag gagaacgugu ggauccagcu gaccuucgac gagagauucg      360

gccuggagga ccccgaggac gacaucugca aguacgacuu cguggaggug gaggagccca      420

gcgacggcac cauccugggc agauggugcg gcagcggcac cgugcccggc aagcagauca      480

gcaagggcaa ccagaucaga aucagauucg ugagcgacga guacuucccc agcgagcccg      540

gcuucugcau ccacuacaac aucgugaugc cccaguucac cgaggccgug agccccagcg      600

ugcugccccc cagcgcccug ccccuggacc ugcugaacaa cgccaucacc gccuucagca      660

cccuggagga ccugaucaga uaccuggagc ccgagagaug gcagcuggac cuggaggacc      720

uguacagacc caccuggcag cugcugggca aggccuucgu guucggcaga aagagcagag      780

ugguggaccu gaaccugcug accgaggagg ugagacugua cagcugcacc cccagaaacu      840

ucagcgugag caucagagag gagcugaaga gaaccgacac caucuucugg cccggcugcc      900

ugcuggugaa gagaugcggc ggcaacugcg ccugcugccu gcacaacugc aacgagugcc      960

agugcgugcc cagcaaggug accaagaagu accacgaggu gcugcagcug agacccaaga     1020

ccggcgugag aggccugcac aagagccuga ccgacguggc ccuggagcac cacgaggagu     1080

gcgacugcgu gugcagaggc agcaccggcg gcugaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  6676
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt4)

<400>  6676
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagacuga ucuucgugua cacccugauc ugcgccaacu      120

ucugcagcug cagagacacc agcgccaccc cccagagcgc cagcaucaag gcccugagaa      180

acgccaaccu gagaagagac gaccuguaca gaagagacga gaccauccag gugaagggca      240

acggcuacgu gcagagcccc agauucccca acagcuaccc cagaaaccug cugcugaccu      300

ggagacugca cagccaggag aacaccagaa uccagcuggu guucgacaac caguucggcc      360

uggaggaggc cgagaacgac aucugcagau acgacuucgu ggagguggag gacaucagcg      420

agaccagcac caucaucaga ggcagauggu gcggccacaa ggaggugccc cccagaauca      480

agagcagaac caaccagauc aagaucaccu ucaagagcga cgacuacuuc guggccaagc      540

ccggcuucaa gaucuacuac agccugcugg aggacuucca gcccgccgcc gccagcgaga      600

ccaacuggga gagcgugacc agcagcauca gcggcgugag cuacaacagc cccagcguga      660

ccgaccccac ccugaucgcc gacgcccugg acaagaagau cgccgaguuc gacaccgugg      720

aggaccugcu gaaguacuuc aaccccgaga gcuggcagga ggaccuggag aacauguacc      780

uggacacccc cagauacaga ggcagaagcu accacgacag aaagagcaag guggaccugg      840

acagacugaa cgacgacgcc aagagauaca gcugcacccc cagaaacuac agcgugaaca      900

ucagagagga gcugaagcug gccaacgugg uguucuuccc cagaugccug cuggugcaga      960

gaugcggcgg caacugcggc ugcggcaccg ugaacuggag aagcugcacc ugcaacagcg     1020

gcaagaccgu gaagaaguac cacgaggugc ugcaguucga gcccggccac aucaagagaa     1080

gaggcagagc caagaccaug gcccuggugg acauccagcu ggaccaccac gagagaugcg     1140

acugcaucug cagcagcaga ccccccagau gaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  6677
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt4)

<400>  6677
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugacccaca gcaaguuccc cgccgccggc augagcagac      120

cccuggacac cagccugaga cugaagaccu ucagcagcaa gagcgaguac cagcuggugg      180

ugaacgccgu gagaaagcug caggagagcg gcuucuacug gagcgccgug accggcggcg      240

aggccaaccu gcugcugagc gccgagcccg ccggcaccuu ccugaucaga gacagcagcg      300

accagagaca cuucuucacc cugagcguga agacccagag cggcaccaag aaccugagaa      360

uccagugcga gggcggcagc uucagccugc agagcgaccc cagaagcacc cagcccgugc      420

ccagauucga cugcgugcug aagcuggugc accacuacau gccccccccc ggcgccccca      480

gcuuccccag cccccccacc gagcccagca gcgaggugcc cgagcagccc agcgcccagc      540

cccugcccgg cagccccccc agaagagccu acuacaucua cagcggcggc gagaagaucc      600

cccuggugcu gagcagaccc cugagcagca acguggccac ccugcagcac cugugcagaa      660

agaccgugaa cggccaccug gacagcuacg agaaggugac ccagcugccc ggccccauca      720

gagaguuccu ggaccaguac gacgcccccc ugugaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  6678
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt4)

<400>  6678
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugcccagcg ccggccagcu ggcccuguuc gcccugggca      120

ucgugcuggc cgccugccag gcccuggaga acagcaccag cccccugagc gccgaccccc      180

ccguggccgc cgccguggug agccacuuca acgacugccc cgacagccac acccaguucu      240

gcuuccacgg caccugcaga uuccuggugc aggaggacaa gcccgccugc gugugccaca      300

gcggcuacgu gggcgccaga ugcgagcacg ccgaccugcu ggccguggug gccgccagcc      360

agaagaagca ggccaucacc gcccuggugg uggugagcau cguggcccug gccgugcuga      420

ucaucaccug cgugcugauc cacugcugcc aggugagaaa gcacugcgag uggugcagag      480

cccugaucug cagacacgag aagcccagcg cccugcugaa gggcagaacc gccugcugcc      540

acagcgagac cgugguguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  6679
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt4)

<400>  6679
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccccagcg gccugagacu gcugccccug cugcugcccc      120

ugcuguggcu gcuggugcug acccccggca gacccgccgc cggccugagc accugcaaga      180

ccaucgacau ggagcuggug aagagaaaga gaaucgaggc caucagaggc cagauccuga      240

gcaagcugag acuggccagc ccccccagcc agggcgaggu gccccccggc ccccugcccg      300

aggccgugcu ggcccuguac aacagcacca gagacagagu ggccggcgag agcgccgagc      360

ccgagcccga gcccgaggcc gacuacuacg ccaaggaggu gaccagagug cugauggugg      420

agacccacaa cgagaucuac gacaaguuca agcagagcac ccacagcauc uacauguucu      480

ucaacaccag cgagcugaga gaggccgugc ccgagcccgu gcugcugagc agagccgagc      540

ugagacugcu gagacugaag cugaaggugg agcagcacgu ggagcuguac cagaaguaca      600

gcaacaacag cuggagauac cugagcaaca gacugcuggc ccccagcgac agccccgagu      660

ggcugagcuu cgacgugacc ggcgugguga gacaguggcu gagcagaggc ggcgagaucg      720

agggcuucag acugagcgcc cacugcagcu gcgacagcag agacaacacc cugcaggugg      780

acaucaacgg cuucaccacc ggcagaagag gcgaccuggc caccauccac ggcaugaaca      840

gacccuuccu gcugcugaug gccacccccc uggagagagc ccagcaccug cagagcagca      900

gacacagaag agcccuggac accaacuacu gcuucagcag caccgagaag aacugcugcg      960

ugagacagcu guacaucgac uucagaaagg accugggcug gaaguggauc cacgagccca     1020

agggcuacca cgccaacuuc ugccugggcc ccugccccua caucuggagc cuggacaccc     1080

aguacagcaa ggugcuggcc cuguacaacc agcacaaccc cggcgccagc gccgcccccu     1140

gcugcgugcc ccaggcccug gagccccugc ccaucgugua cuacgugggc agaaagccca     1200

agguggagca gcugagcaac augaucguga gaagcugcaa gugcagcuga ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  6680
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt4)

<400>  6680
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg ugcugagcgc cuuccugauc cugcaccugg      120

ugaccguggc ccugagccug agcaccugca gcacccugga cauggaccag uucaugagaa      180

agagaaucga ggccaucaga ggccagaucc ugagcaagcu gaagcugacc agcccccccg      240

aggacuaccc cgagcccgag gaggugcccc ccgaggugau cagcaucuac aacagcacca      300

gagaccugcu gcaggagaag gccagcagaa gagccgccgc cugcgagaga gagagaagcg      360

acgaggagua cuacgccaag gagguguaca agaucgacau gccccccuuc uuccccagcg      420

agaacgccau cccccccacc uucuacagac ccuacuucag aaucgugaga uucgacguga      480

gcgccaugga gaagaacgcc agcaaccugg ugaaggccga guucagagug uucagacugc      540

agaaccccaa ggccagagug cccgagcaga gaaucgagcu guaccagauc cugaagagca      600

aggaccugac cagccccacc cagagauaca ucgacagcaa gguggugaag accagagccg      660

agggcgagug gcugagcuuc gacgugaccg acgccgugca cgaguggcug caccacaagg      720

acagaaaccu gggcuucaag aucagccugc acugccccug cugcaccuuc gugcccagca      780

acaacuacau cauccccaac aagagcgagg agcuggaggc cagauucgcc ggcaucgacg      840

gcaccagcac cuacaccagc ggcgaccaga agaccaucaa gagcaccaga aagaagaaca      900

gcggcaagac cccccaccug cugcugaugc ugcugcccag cuacagacug gagagccagc      960

agaccaacag aagaaagaag agagcccugg acgccgccua cugcuucaga aacgugcagg     1020

acaacugcug ccugagaccc cuguacaucg acuucaagag agaccugggc uggaagugga     1080

uccacgagcc caagggcuac aacgccaacu ucugcgccgg cgccugcccc uaccugugga     1140

gcagcgacac ccagcacagc agagugcuga gccuguacaa caccaucaac cccgaggcca     1200

gcgccagccc cugcugcgug agccaggacc uggagccccu gaccauccug uacuacaucg     1260

gcaagacccc caagaucgag cagcugagca acaugaucgu gaagagcugc aagugcagcu     1320

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  6681
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt4)

<400>  6681
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacc ugcagagagc ccugguggug cuggcccugc      120

ugaacuucgc caccgugagc cugagccuga gcaccugcac cacccuggac uucggccaca      180

ucaagaagaa gagaguggag gccaucagag gccagauccu gagcaagcug agacugacca      240

gcccccccga gcccaccgug augacccacg ugcccuacca ggugcuggcc cuguacaaca      300

gcaccagaga gcugcuggag gagaugcacg gcgagagaga ggagggcugc acccaggaga      360

acaccgagag cgaguacuac gccaaggaga uccacaaguu cgacaugauc cagggccugg      420

ccgagcacaa cgagcuggcc gugugcccca agggcaucac cagcaaggug uucagauuca      480

acgugagcag cguggagaag aacagaacca accuguucag agccgaguuc agagugcuga      540

gagugcccaa ccccagcagc aagagaaacg agcagagaau cgagcuguuc cagauccuga      600

gacccgacga gcacaucgcc aagcagagau acaucggcgg caagaaccug cccaccagag      660

gcaccgccga guggcugagc uucgacguga ccgacaccgu gagagagugg cugcugagaa      720

gagagagcaa ccugggccug gagaucagca uccacugccc cugccacacc uuccagccca      780

acggcgacau ccuggagaac auccacgagg ugauggagau caaguucaag ggcguggaca      840

acgaggacga ccacggcaga ggcgaccugg gcagacugaa gaagcagaag gaccaccaca      900

acccccaccu gauccugaug augauccccc cccacagacu ggacaacccc ggccagggcg      960

gccagagaaa gaagagagcc cuggacacca acuacugcuu cagaaaccug gaggagaacu     1020

gcugcgugag accccuguac aucgacuuca gacaggaccu gggcuggaag ugggugcacg     1080

agcccaaggg cuacuacgcc aacuucugca gcggccccug ccccuaccug agaagcgccg     1140

acaccaccca cagcaccgug cugggccugu acaacacccu gaaccccgag gccagcgcca     1200

gccccugcug cgugccccag gaccuggagc cccugaccau ccuguacuac gugggcagaa     1260

cccccaaggu ggagcagcug agcaacaugg uggugaagag cugcaagugc agcugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6682
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt4)

<400>  6682
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccccgugg ccgugugggc cgcccuggcc gugggccugg      120

agcugugggc cgccgcccac gcccugcccg cccagguggc cuucaccccc uacgcccccg      180

agcccggcag caccugcaga cugagagagu acuacgacca gaccgcccag augugcugca      240

gcaagugcag ccccggccag cacgccaagg uguucugcac caagaccagc gacaccgugu      300

gcgacagcug cgaggacagc accuacaccc agcuguggaa cugggugccc gagugccuga      360

gcugcggcag cagaugcagc agcgaccagg uggagaccca ggccugcacc agagagcaga      420

acagaaucug caccugcaga cccggcuggu acugcgcccu gagcaagcag gagggcugca      480

gacugugcgc cccccugaga aagugcagac ccggcuucgg cguggccaga cccggcaccg      540

agaccagcga cguggugugc aagcccugcg cccccggcac cuucagcaac accaccagca      600

gcaccgacau cugcagaccc caccagaucu gcaacguggu ggccaucccc ggcaacgcca      660

gcauggacgc cgugugcacc agcaccagcc ccaccagaag cauggccccc ggcgccgugc      720

accugcccca gcccgugagc accagaagcc agcacaccca gcccaccccc gagcccagca      780

ccgcccccag caccagcuuc cugcugccca ugggccccag cccccccgcc gagggcagca      840

ccggcgacuu cgcccugccc gugggccuga ucgugggcgu gaccgcccug ggccugcuga      900

ucaucggcgu ggugaacugc gugaucauga cccaggugaa gaagaagccc cugugccugc      960

agagagaggc caaggugccc caccugcccg ccgacaaggc cagaggcacc cagggccccg     1020

agcagcagca ccugcugauc accgccccca gcagcagcag cagcagccug gagagcagcg     1080

ccagcgcccu ggacagaaga gcccccacca gaaaccagcc ccaggccccc ggcguggagg     1140

ccagcggcgc cggcgaggcc agagccagca ccggcagcag cgacagcagc cccggcggcc     1200

acggcaccca ggugaacgug accugcaucg ugaacgugug cagcagcagc gaccacagca     1260

gccagugcag cagccaggcc agcagcacca ugggcgacac cgacagcagc cccagcgaga     1320

gccccaagga cgagcaggug cccuucagca aggaggagug cgccuucaga agccagcugg     1380

agacccccga gacccugcug ggcagcaccg aggagaagcc ccugccccug ggcgugcccg     1440

acgccggcau gaagcccagc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  6683
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt4)

<400>  6683
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgugauga gacuguuccc cugcuuccug cagcugcugg      120

ccggccuggc ccugcccgcc gugccccccc agcagugggc ccugagcgcc ggcaacggca      180

gcagcgaggu ggagguggug cccuuccagg aggugugggg cagaagcuac ugcagagccc      240

uggagagacu gguggacgug gugagcgagu accccagcga gguggagcac auguucagcc      300

ccagcugcgu gagccugcug agaugcaccg gcugcugcgg cgacgagaac cugcacugcg      360

ugcccgugga gaccgccaac gugaccaugc agcugcugaa gaucagaagc ggcgacagac      420

ccagcuacgu ggagcugacc uucagccagc acgugagaug cgagugcaga ccccugagag      480

agaagaugaa gcccgagaga agaagaccca agggcagagg caagagaaga agagagaagc      540

agagacccac cgacugccac cugugcggcg acgccgugcc cagaagauga ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  6684
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt4)

<400>  6684
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgacagac agaccgacac cgcccccagc cccagcuacc      120

accugcugcc cggcagaaga agaaccgugg acgccgccgc cagcagaggc cagggccccg      180

agcccgcccc cggcggcggc guggagggcg ugggcgccag aggcguggcc cugaagcugu      240

ucgugcagcu gcugggcugc agcagauucg gcggcgccgu ggugagagcc ggcgaggccg      300

agcccagcgg cgccgccaga agcgccagca gcggcagaga ggagccccag cccgaggagg      360

gcgaggagga ggaggagaag gaggaggaga gaggccccca guggagacug ggcgccagaa      420

agcccggcag cuggaccggc gaggccgccg ugugcgccga cagcgccccc gccgccagag      480

ccccccaggc ccuggccaga gccagcggca gaggcggcag aguggccaga agaggcgccg      540

aggagagcgg ccccccccac agccccagca gaagaggcag cgccagcaga gccggccccg      600

gcagagccag cgagaccaug aacuuccugc ugagcugggu gcacuggagc cuggcccugc      660

ugcuguaccu gcaccacgcc aaguggagcc aggccgcccc cauggccgag ggcggcggcc      720

agaaccacca cgagguggug aaguucaugg acguguacca gagaagcuac ugccacccca      780

ucgagacccu gguggacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      840

ccagcugcgu gccccugaug agaugcggcg gcugcugcaa cgacgagggc cuggagugcg      900

ugcccaccga ggagagcaac aucaccaugc agaucaugag aaucaagccc caccagggcc      960

agcacaucgg cgagaugagc uuccugcagc acaacaagug cgagugcaga cccaagaagg     1020

acagagccag acaggagaag aagagcguga gaggcaaggg caagggccag aagagaaaga     1080

gaaagaagag cagauacaag agcuggagcg uguacguggg cgccagaugc ugccugaugc     1140

ccuggagccu gcccggcccc caccccugcg gccccugcag cgagagaaga aagcaccugu     1200

ucgugcagga cccccagacc ugcaagugca gcugcaagaa caccgacagc agaugcaagg     1260

ccagacagcu ggagcugaac gagagaaccu gcagaugcga caagcccaga agaugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6685
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt4)

<400>  6685
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ugagcugggu gcacuggagc cuggcccugc      120

ugcuguaccu gcaccacgcc aaguggagcc aggccgcccc cauggccgag ggcggcggcc      180

agaaccacca cgagguggug aaguucaugg acguguacca gagaagcuac ugccacccca      240

ucgagacccu gguggacauc uuccaggagu accccgacga gaucgaguac aucuucaagc      300

ccagcugcgu gccccugaug agaugcggcg gcugcugcaa cgacgagggc cuggagugcg      360

ugcccaccga ggagagcaac aucaccaugc agaucaugag aaucaagccc caccagggcc      420

agcacaucgg cgagaugagc uuccugcagc acaacaagug cgagugcaga cccaagaagg      480

acagagccag acaggagaag aagagcguga gaggcaaggg caagggccag aagagaaaga      540

gaaagaagag cagauacaag agcuggagcg uguacguggg cgccagaugc ugccugaugc      600

ccuggagccu gcccggcccc caccccugcg gccccugcag cgagagaaga aagcaccugu      660

ucgugcagga cccccagacc ugcaagugca gcugcaagaa caccgacagc agaugcaagg      720

ccagacagcu ggagcugaac gagagaaccu gcagaugcga caagcccaga agaugaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  6686
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt4)

<400>  6686
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcccccugc ugagaagacu gcugcuggcc gcccugcugc      120

agcuggcccc cgcccaggcc cccgugagcc agcccgacgc ccccggccac cagagaaagg      180

uggugagcug gaucgacgug uacaccagag ccaccugcca gcccagagag gugguggugc      240

cccugaccgu ggagcugaug ggcaccgugg ccaagcagcu ggugcccagc ugcgugaccg      300

ugcagagaug cggcggcugc ugccccgacg acggccugga gugcgugccc accggccagc      360

accaggugag aaugcagauc cugaugauca gauaccccag cagccagcug ggcgagauga      420

gccuggagga gcacagccag ugcgagugca gacccaagaa gaaggacagc gccgugaagc      480

ccgacagagc cgccaccccc caccacagac cccagcccag aagcgugccc ggcugggaca      540

gcgcccccgg cgcccccagc cccgccgaca ucacccaccc cacccccgcc cccggcccca      600

gcgcccacgc cgcccccagc accaccagcg cccugacccc cggccccgcc gccgccgccg      660

ccgacgccgc cgccagcagc guggccaagg gcggcgccug aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  6687
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt4)

<400>  6687
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccugcugg gcuucuucag cguggccugc agccugcugg      120

ccgccgcccu gcugcccggc cccagagagg cccccgccgc cgccgccgcc uucgagagcg      180

gccuggaccu gagcgacgcc gagcccgacg ccggcgaggc caccgccuac gccagcaagg      240

accuggagga gcagcugaga agcgugagca gcguggacga gcugaugacc gugcuguacc      300

ccgaguacug gaagauguac aagugccagc ugagaaaggg cggcuggcag cacaacagag      360

agcaggccaa ccugaacagc agaaccgagg agaccaucaa guucgccgcc gcccacuaca      420

acaccgagau ccugaagagc aucgacaacg aguggagaaa gacccagugc augcccagag      480

aggugugcau cgacgugggc aaggaguucg gcguggccac caacaccuuc uucaagcccc      540

ccugcgugag cguguacaga ugcggcggcu gcugcaacag cgagggccug cagugcauga      600

acaccagcac cagcuaccug agcaagaccc uguucgagau caccgugccc cugagccagg      660

gccccaagcc cgugaccauc agcuucgcca accacaccag cugcagaugc augagcaagc      720

uggacgugua cagacaggug cacagcauca ucagaagaag ccugcccgcc acccugcccc      780

agugccaggc cgccaacaag accugcccca ccaacuacau guggaacaac cacaucugca      840

gaugccuggc ccaggaggac uucauguuca gcagcgacgc cggcgacgac agcaccgacg      900

gcuuccacga caucugcggc cccaacaagg agcuggacga ggagaccugc cagugcgugu      960

gcagagccgg ccugagaccc gccagcugcg gcccccacaa ggagcuggac agaaacagcu     1020

gccagugcgu gugcaagaac aagcuguucc ccagccagug cggcgccaac agagaguucg     1080

acgagaacac cugccagugc gugugcaaga gaaccugccc cagaaaccag ccccugaacc     1140

ccggcaagug cgccugcgag ugcaccgaga gcccccagaa gugccugcug aagggcaaga     1200

aguuccacca ccagaccugc agcugcuaca gaagacccug caccaacaga cagaaggccu     1260

gcgagcccgg cuucagcuac agcgaggagg ugugcagaug cgugcccagc uacuggaaga     1320

gaccccagau gagcugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  6688
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt4)

<400>  6688
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagagu gggugguggu gaacguguuc augaugcugu      120

acgugcagcu ggugcagggc agcagcaacg agcacggccc cgugaagaga agcagccaga      180

gcacccugga gagaagcgag cagcagauca gagccgccag cagccuggag gagcugcuga      240

gaaucaccca cagcgaggac uggaagcugu ggagaugcag acugagacug aagagcuuca      300

ccagcaugga cagcagaagc gccagccaca gaagcaccag auucgccgcc accuucuacg      360

acaucgagac ccugaaggug aucgacgagg aguggcagag aacccagugc agccccagag      420

agaccugcgu ggagguggcc agcgagcugg gcaagagcac caacaccuuc uucaagcccc      480

ccugcgugaa cguguucaga ugcggcggcu gcugcaacga ggagagccug aucugcauga      540

acaccagcac cagcuacauc agcaagcagc uguucgagau cagcgugccc cugaccagcg      600

ugcccgagcu ggugcccgug aagguggcca accacaccgg cugcaagugc cugcccaccg      660

cccccagaca ccccuacagc aucaucagaa gaagcaucca gauccccgag gaggacagau      720

gcagccacag caagaagcug ugccccaucg acaugcugug ggacagcaac aagugcaagu      780

gcgugcugca ggaggagaac ccccuggccg gcaccgagga ccacagccac cugcaggagc      840

ccgcccugug cggcccccac augauguucg acgaggacag augcgagugc gugugcaaga      900

cccccugccc caaggaccug auccagcacc ccaagaacug cagcugcuuc gagugcaagg      960

agagccugga gaccugcugc cagaagcaca agcuguucca ccccgacacc ugcagcugcg     1020

aggacagaug ccccuuccac accagacccu gcgccagcgg caagaccgcc ugcgccaagc     1080

acugcagauu ccccaaggag aagagagccg cccagggccc ccacagcaga aagaaccccu     1140

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  6689
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt5)

<400>  6689
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgaug agaccggcuu cgaacacucc gggcuguggg      120

ugucuguccu cgccggacug cuucugggcg cuugccaggc ccaucccauc ccugacagcu      180

ccccgcuccu gcaauuuggg ggacagguua gacagcggua ccuuuauaca gaugacgcgc      240

agcaaacgga ggcucaccug gaaauucgcg aggauggcac cgugggcgga gccgccgacc      300

agucucccga aagccuccug cagcugaagg cucucaaacc uggcgugauc cagauucugg      360

gcgucaagac auccagauuc cuuugucaac ggcccgaugg ggcccuguac ggaucucucc      420

auuuugaccc ugaggcuugc agcuuccgcg agcugcuucu ggaagauggc uauaacgugu      480

accaguccga ggcccacggg cucccccugc aucugccugg aaauaaaagc ccgcacagag      540

accccgcgcc ucggggcccc gcccgcuuuc ucccucugcc cgggcuuccg ccugcucugc      600

ccgaaccucc cggaauccuc gcuccccagc cuccggaugu ugggucuucc gacccccuga      660

gcaugguggg cccuucucag gggagauccc ccagcuaugc cucuugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  6690
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt5)

<400>  6690
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc ccccucugcu ccugcuucug uucuggggcg      120

uggucuccca uucuuucccg gccacccucg agacacagga acaagacguu gaucuggugc      180

agaaguaccu ugagaaauau uacaaccuga agaaugacgg gagacaggug gaaaaacggc      240

gcaacagcgg acccgucgug gagaagcuca aacagaugca agaauuuuuc ggccugaagg      300

uuacggggaa gccugaugcu gagacccuga aagugaugaa gcagcccaga ugcggagucc      360

cugacguggc ccaguuuguu cucacagagg gcaauccccg gugggaacag acccaccuga      420

cauaucgcau cgagaacuac accccugauc uuccgagagc ggacguggau caugcuauug      480

aaaaagccuu ccaacugugg uccaauguca caccccucac cuuuacgaag gugucugagg      540

ggcaggccga caucaugauu agcuucgugc ggggagauca ccgcgacaac uccccuuuug      600

auggccccgg cgggaaucug gcucaugccu uccagccugg acccggcauc gggggagacg      660

cucacuuuga ugaggacgaa agauggacca acaauuuccg ggaguauaac cuucaccgcg      720

ucgccgcgca ugaacugggc cacucucucg ggcugagcca uuccacagac auuggagccc      780

ugauguaccc gagcuauacc uuuucuggcg auguucagcu cgcucaagac gauaucgacg      840

gcauccaggc cauuuacggg agaucccaga auccugugca acccaucgga ccucagacac      900

ccaaggcuug ugauagcaaa cugaccuucg acgccauuac gacaauccgg ggcgagguga      960

uguucuuuaa ggaucgcuuc uacaugagaa ccaaccccuu uuauccugaa gucgagcuua     1020

auuucauuuc uguguuuugg ccgcagcugc ccaacgggcu cgaggcggcc uacgaguucg     1080

cugaccggga ugaaguucgc uuuuucaaag gaaauaagua uugggccgug cagggccaaa     1140

acguccugca cggguacccu aaagacaucu auuccagcuu uggauucccc agaacaguga     1200

agcacauuga ugcugcccuu ucugaagaga acaccggcaa aaccuacuuu uucguugcca     1260

auaaguauug gcgguacgac gaauacaaaa gauccaugga cccuggcuau cccaagauga     1320

ucgcucauga uuuuccgggg aucggacaca agguggacgc ggucuucaug aaagauggcu     1380

ucuuuuacuu cuuucauggg acacgccagu auaaguucga cccuaaaacg aagcggauuc     1440

ugacccucca gaaagccaac agcugguuua auugcagaaa gaacugagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  6691
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt5)

<400>  6691
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc ccccucugcu ccugcuucug uucuggggcg      120

uggucuccca uucuuucguu cucaccgagg ggaacccgag augggaacag acacaccuga      180

cguaccggau ugagaauuau acccccgacc uuccucgcgc cgauguggac caugcuauug      240

aaaaggccuu ucaacugugg agcaacguga caccccucac cuucacaaaa gucuccgagg      300

gacaggcgga uaucaugauu ucuuuuguga gaggcgacca ccgggauaau agcccuuucg      360

acgggcccgg aggcaaccug gcucaugccu uucagccugg gccgggaauc ggcggcgaug      420

cccacuucga cgaagaugag cgcuggacca auaacuuuag agaguacaau cugcaccggg      480

uugcugccca ugaacucggg cacucccugg gacuuucuca uagcacagac auuggcgcuc      540

ugauguaucc cuccuacacc uucagcgggg augugcagcu cgcccaagac gauaucgacg      600

gaauccaggc gauuuauggc cgcucucaga acccugucca gcccaucggg ccucaaacgc      660

ccaaggccug cgacuccaaa cugaccuuug augcuauuac aaccaucaga ggagagguga      720

uguucuuuaa ggaccgguuc uacaugcgca caaauccguu cuauccugaa guugagcuua      780

acuuuauuag cguguucugg ccccagcugc cuaauggccu cgaggccgcu uacgaauuug      840

ccgauagaga cgagguccgg uucuuuaaag gcaacaagua cugggcggug caggggcaga      900

augugcugca cggauauccc aaggauaucu acucuuccuu cggcuuuccc cgcaccguca      960

aacacauuga cgccgcucug agcgaagaga acacggggaa gacauauuuc uuuguugcca     1020

auaaauacug gagauaugau gaauacaagc ggucuaugga cccuggauau ccgaaaauga     1080

ucgcucauga uuuccccggc aucgggcaca agguggacgc cguguuuaug aaggauggau     1140

ucuuuuacuu cuuccauggc acccgccaau acaaauuuga cccuaagaca aaaagaaucc     1200

ucacccugca gaaggccaac uccugguuca acugucggaa aaauugagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  6692
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt5)

<400>  6692
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaaaaaca uccugaagau ucucauggac agcuacucca      120

aagagucuaa gauccagacc gugagacggg ucacaagcgu uucccugcuu gccguguauc      180

ugacgaugaa uaccucuagc cucgugcugg cuaaacccau ugaaaacaca aaugauaccu      240

ccaucaagaa cgucgagaaa cuucgcaaug ccccuaacga agaaaauucu aaaaaggugg      300

aagacagcaa aaacgauaag guugagcacg ugaaaaauau ugaggaagcg aaggucgagc      360

aaguggcucc ggaaguuaag uccaaaagca cacugagauc ugccuccauc gccaacacca      420

auagcgagaa guacgacuuc gaguaucuca acggccuguc uuacacagaa cugaccaauc      480

ucaucaaaaa cauuaagugg aaucagauca acgggcuguu uaacuauucc acgggaagcc      540

agaaauucuu uggcgauaag aaucgggugc aggcuauuau caacgcccuu caagagucug      600

ggcgcaccua cacagcuaau gacaugaaag gaauugaaac cuucacagag guccugagag      660

ccggcuuuua ucucggguac uacaacgaug gacuguccua ucuuaaugac cggaacuucc      720

aggauaagug cauccccgcg augauugcca uccagaagaa uccuaacuuu aaacugggca      780

ccgcugugca ggacgaagug aucacgagcc ucggcaagcu gauugggaau gccuccgcua      840

acgccgaggu cguuaauaac ugugugcccg ugcugaaaca auuccgcgag aaucucaacc      900

aguacgcgcc ugauuauguc aagggaacag ccgugaauga acugaucaaa ggcauugagu      960

uugacuucuc uggggcugcc uacgaaaagg auguuaagac caugcccugg uauggaaaaa     1020

ucgacccuuu uauuaacgag cuuaaggcuc ugggccucua cgggaacauc acaagcgcca     1080

ccgaaugggc cuccgacgug ggaaucuauu accugagcaa auucggccuu uacucuacca     1140

auagaaacga uauuguccag ucccuggaga aggcugugga cauguauaaa uacggcaaga     1200

ucgcguuugu ugccauggag cggauuacau gggauuauga cgggaucgga agcaauggca     1260

agaaagugga ucaugacaag uuccucgaug acgcugaaaa acacuaccug ccgaagacgu     1320

auaccuucga uaacgggaca uuuauuaucc gcgccggaga caaagucucu gaggaaaaga     1380

ucaagagacu guacugggcc agccgggagg ugaaauccca guuccaucgc gucgugggca     1440

augauaaggc ucucgaaguu gggaacgccg acgacgugcu gaccaugaaa auuuuuaauu     1500

cucccgagga guauaaguuc aacacaaaua ucaacggagu cagcaccgau aauggcggcc     1560

uuuacauuga accuagaggg acguuuuaca cauaugagcg gacaccccaa caguccaucu     1620

ucagccugga ggagcucuuu cgccacgagu acacccauua ucugcaggcg agauaccuug     1680

uggacggacu guggggccaa gggccuuucu augagaaaaa ccggcucacc ugguuugaug     1740

aaggaaccgc ugaguucuuu gccggcucua caagaacguc cgggguucug ccccgcaaga     1800

gcauucuggg cuaccucgcc aaagacaagg uggaucaccg guauucucug aagaaaaccc     1860

uuaauuccgg auacgacgau agcgacugga uguucuacaa cuauggcuuu gcugucgccc     1920

acuaccugua ugaaaaggau augccgacau ucaucaaaau gaauaaggcu auucucaaca     1980

ccgacgugaa auccuacgau gaaaucauca agaagcuguc ugacgaugcc aacaaaaaua     2040

cagaguauca gaaccauauu caggagcugg cggacaagua ccagggggcc ggaaucccuc     2100

uugugagcga cgauuaucuc aaagaccacg gcuacaagaa ggcuuccgaa guuuacucug     2160

agauuagcaa ggccgcuucc cugaccaaua cgagcgucac cgccgaaaag ucucaauauu     2220

ucaacacauu uacccugaga gggacauaca ccggagagac guccaaaggc gaguucaagg     2280

auugggacga aaugagcaaa aagcucgaug ggacacugga gucucuugcg aaaaauuccu     2340

ggagcggcua uaagacccug acagccuacu uuaccaacua ucgcgugacc ucugacaaua     2400

aggugcagua cgaugucgug uuccauggag uucucacaga caacgcugau aucagcaaua     2460

acaaagcccc cauugcuaag gugacgggcc cuuccaccgg ggccgucgga cggaauaucg     2520

aauuuagcgg caaagacucu aaggaugagg acgggaaaau cguguccuau gauugggacu     2580

ucggagacgg cgccacaagc agagggaaga acuccguuca cgcuuacaaa aaggcgggca     2640

ccuacaaugu gacacugaag gucaccgaug acaaaggagc cacggcuaca gaaucuuuua     2700

ccauugagau caagaacgaa gauaccacaa cccccauuac aaaagagaug gagcccaaug     2760

acgauaucaa ggaagccaac ggcccuauug uggagggggu uacggugaaa ggagaccuga     2820

acggcagcga ugacgccgau accuucuauu uugacgucaa ggaagauggg gacgugacaa     2880

ucgagcuucc guacuccgga ucuagcaauu ucaccuggcu cguguauaag gagggcgacg     2940

aucagaacca caucgcuucc gggauugaca aaaauaacuc uaaggucggc acauuuaaaa     3000

gcaccaaggg acgccauuac guuuucaucu auaaacacga uuccgccagc aauauuucuu     3060

acucccugaa caucaagggc cuggggaaug aaaagcucaa agagaaggaa aacaaugaca     3120

gcucugauaa agcgacggug auucccaacu uuaauaccac aaugcaggga ucccugcuug     3180

gcgacgauag ccgggacuau uacucuuucg aggugaagga agagggggag gucaacaucg     3240

aacuggauaa aaaggacgag uucggaguga ccuggacacu ccauccugaa uccaauauca     3300

acgauagaau uaccuacggc caaguugacg gcaauaaggu gagcaacaaa gucaagcugc     3360

gccccgggaa auauuaccug cuuguguaua aguacuccgg aagcggcaau uaugagcucc     3420

ggguuaacaa augaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  6693
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt5)

<400>  6693
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucuccu      120

cugccuacag cauugcuaac acaaauuccg agaaauauga cuuugaauac cuuaacggcc      180

ugucuuauac ggagcucacc aaucugauca agaacauuaa auggaaucag aucaacgggc      240

uuuucaauua cagcacagga ucccaaaagu uuuucggcga uaaaaacaga guccaggcca      300

uuaucaaugc gcugcaggaa ucugggcgga ccuauacagc uaacgacaug aagggaaucg      360

agaccuuuac agaaguucuc cgcgccggcu ucuaccuggg guauuacaau gauggacuga      420

gcuaccucaa cgacagaaau uuucaggaua agugcauucc cgccaugauc gcuauucaga      480

aaaacccuaa uuucaagcug ggcaccgccg ugcaagacga ggugaucacg ucccuuggca      540

aacugauugg gaacgcuagc gccaacgcgg aggucgugaa uaacuguguu ccggugcuca      600

agcaguuucg ggaaaaucug aaccaguaug cccccgauua cgucaaagga accgcuguga      660

augagcuuau caagggcauu gaguucgacu uuucuggggc cgcuuaugaa aaggauguua      720

aaacaaugcc uugguacgga aagaucgacc ccuucaucaa cgagcugaaa gcccucggcc      780

uguaugggaa uauuaccucc gcgacagaau gggccagcga ugugggaauc uacuaucugu      840

cuaaguucgg ccucuacucc accaaccgca augacauugu ccaaagccug gagaaagcug      900

uggauaugua caaguauggc aaaaucgccu uuguggcuau ggaaagaauu acgugggacu      960

acgacgggau cggaucuaac ggcaagaagg ucgaucacga caaauuccuu gaugacgccg     1020

agaagcauua ucugccuaaa acauacaccu uugauaaugg gacauucauc auucgggccg     1080

gagacaaggu uuccgaagag aaaaucaagc gccucuauug ggcuagcaga gaggugaagu     1140

cccaguuuca ccgggugguc ggcaacgaua aagcgcugga aguggggaau gccgacgaug     1200

uucuuaccau gaagauuuuc aacucucccg aggaauacaa auuuaauacc aacaucaacg     1260

gagugagcac agacaauggc ggccuguaua uugagccucg cgggacguuc uacaccuacg     1320

aaagaacacc gcagcagucc aucuuuagcc ucgaggagcu guuccggcau gaauauaccc     1380

acuaccugca agcucgcuau cucgucgaug gacugugggg ccaggggccc uuuuacgaga     1440

agaacagacu uacaugguuc gacgaaggaa ccgccgaguu uuucgccggc ucuacgcgga     1500

cauccggggu gcugccucgc aaaagcaucc ucggcuaucu ggcuaaggac aagguugauc     1560

auagauacuc ucuuaaaaag acccugaaua gcggauauga cgauuccgac uggauguucu     1620

acaacuacgg cuuugccgug gcgcacuauc ucuacgaaaa agauaugccc accuucauua     1680

agaugaauaa agcuauccug aacacagacg ucaagucuua ugaugagauu aucaagaaac     1740

ugagcgacga ugccaauaag aacaccgagu accagaauca cauucaagaa cucgccgaca     1800

aauaucaggg ggcuggaauc ccucuggugu ccgaugacua ccuuaaggau cauggcuaua     1860

aaaaggccag cgaggucuac ucugaaauuu ccaaagcugc cagccugaca aacacgucug     1920

ugaccgcgga gaagucccag uacuuuaaua cauucacccu ccgggggaca uauaccggag     1980

agacgagcaa gggcgaauuu aaagacuggg acgagauguc caagaaacug gaugggaccc     2040

uggaaucucu ugccaagaac agcugguccg gcuacaaaac acucaccgcu uauuucacaa     2100

auuacagagu uaccucugac aacaaggugc aguaugaugu cguguuucac ggaguucuga     2160

cggacaaugc cgauaucagc aacaacaagg cucccaucgc caaagugaca ggcccgucca     2220

ccggggcggu cggacgcaau auugaguuca gcggcaagga cucuaaagau gaagacggga     2280

agaucguguc cuacgauugg gacuuuggag auggcgccac aagccggggg aaaaacucug     2340

ugcaugcuua uaagaaggcc ggcaccuaca auguuacccu gaaagucaca gacgauaagg     2400

gagcuacggc caccgagucc uucacaauug agaucaaaaa cgaagacacc acaaccccua     2460

uuacgaagga gauggaaccc aaugacgaua ucaaagaggc caacggcccu aucguggaag     2520

gggugacagu caagggagac cucaauggca gcgaugacgc ugauaccuuu uacuucgacg     2580

ugaaggagga uggggacguu accauugagc ugcccuauuc uggaagcucc aacuuuacau     2640

ggcuugugua caaagaaggc gaugaccaaa aucacaucgc gagcgggauu gauaagaaca     2700

auucuaaagu cggcaccuuc aaguccacaa aaggaagaca cuauguguuc aucuacaagc     2760

augacagcgc cuccaacauu ucuuauagcc ugaauaucaa aggccucggg aacgagaagc     2820

ugaaggaaaa agagaauaac gacuccucug auaaggcuac gguuaucccc aacuuuaaua     2880

ccacaaugca gggaagccug cuuggcgacg auucccgcga cuacuauucu uucgaaguga     2940

aagaggaggg ggaagucaac auugagcucg auaagaaaga cgaauuugga gugaccugga     3000

cacugcaccc ugagagcaau aucaacgauc ggauuaccua cggccagguu gacggcaaua     3060

agguguccaa caaggucaaa cugagaccgg ggaaguacua ucuccuggug uacaaauaua     3120

gcggaucugg caauuacgag cuucgcguga acaagugagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  6694
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt5)

<400>  6694
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucuccu      120

cugccuacag caugaaaaag aacauucuua aaauccugau ggacuccuau ucuaaggaga      180

gcaaaauuca gacagucaga cggguuacgu ccgugucucu ccuggcugug uaccuuacca      240

ugaauacaag cucccugguc cucgccaagc ccaucgaaaa caccaaugau acaagcauua      300

agaacgugga gaaacugcgc aaugcgccua acgaagaaaa uucuaagaaa guugaagacu      360

ccaagaacga uaaaguggag cacgucaaga auaucgagga agcuaaggug gagcaaguug      420

ccccggaagu gaaaagcaag ucuacccuga gauccgccag ccggcgcaga cggaaacgca      480

ucgcuaacac aaauucugag aaguaugacu uugaguaccu caacggccug uccuauaccg      540

aacuuacgaa ucugauuaaa aacaucaagu ggaaucagau uaacggacuc uucaacuaca      600

gcaccggauc ccagaaauuu uucggcgaua agaauagagu ccaggccauc auuaacgcuc      660

ugcaagaguc ugggcggaca uauaccgcca augacaugaa gggaaucgaa acauuuaccg      720

aggugcuucg cgcgggcuuc uaccuggggu acuauaacga uggacucagc uaccugaaug      780

acagaaacuu ucaggauaaa ugcauucccg ccaugaucgc uauccagaag aauccuaacu      840

ucaaacuggg cacggccgug caggacgaag ucauuacauc ccucggcaag cugaucggga      900

augcuagcgc caacgcggag guugugaaua acugugugcc cguccuuaaa caauuucggg      960

agaaucugaa ccaguaugcc ccugauuacg ugaagggaac cgcuguuaau gaacucauua     1020

agggcaucga guucgacuuu ucuggggccg cuuaugaaaa agaugugaag acaaugcccu     1080

gguacggaaa aauugacccu uucaucaacg agcugaaggc ccuuggccug uaugggaaca     1140

ucaccuccgc caccgaaugg gcuagcgacg ucggaauuua cuaccucucu aaauucggcc     1200

uguauagcac aaaucgcaac gauaucgugc agucccugga gaaggcgguu gacauguaca     1260

aguauggcaa aauugccuuu guggcuaugg agagaaucac gugggauuac gacgggauug     1320

gaucuaaugg caagaaaguc gaucaugaca aguuccucga ugacgccgaa aaacacuauc     1380

ugccgaagac cuacacauuu gauaacggga ccuucaucau ccgggccgga gacaagguga     1440

gcgaggaaaa gauuaagcgc cuuuauuggg cuuccagaga ggucaaaagc caguuucauc     1500

gggugguugg caaugauaag gcccuggaag uggggaacgc ggacgacguc cucacaauga     1560

aaaucuucaa uucucccgag gaguacaagu uuaacaccaa uauuaacgga guguccacgg     1620

auaauggcgg ccuguacauc gaaccuagag ggacauucua uaccuacgag cgcacacccc     1680

aacagagcau uuuuagccuu gaggagcugu uccggcacga guauacccau uaccuccagg     1740

cuagauaucu gguugacgga cuguggggcc aagggccuuu uuacgagaaa aaccgccuca     1800

ccugguucga ugaaggaaca gccgaauuuu ucgccggcuc cacgcggacc agcggggugc     1860

ugcccagaaa guccauccuu ggcuaucugg cuaaggacaa agucgaucac cgcuacucuc     1920

ucaagaaaac acugaauagc ggauacgacg auuccgacug gauguucuau aacuacggcu     1980

uugccguggc ucacuaucug uacgagaagg auaugccgac cuucauuaaa augaauaagg     2040

ccauccuuaa cacagacgug aagucuuaug augaaaucau uaaaaagcuc agcgacgaug     2100

cgaacaaaaa uaccgaguac cagaaccaua uccaggagcu ggccgacaag uaucaggggg     2160

cugggauucc ucugguuucc gacgauuacc ucaaagacca cggcuacaag aaggccagcg     2220

aagucuauuc ugagaucucc aaagcugcca gccugacgaa uaccucugug acagcggaaa     2280

agucccaaua cuuuaacacc uucacacuuc gggggaccua uacgggagag acaagcaaag     2340

gcgaauuuaa ggauugggac gagaugucua aaaagcugga ugggacccuc gagagccugg     2400

ccaaaaauuc cuggagcggc uacaaaacac ugaccgcuua uuucaccaac uacagaguga     2460

caucugacaa uaagguccag uaugaugugg uuuuucaugg agugcuuacg gacaacgccg     2520

auauuuccaa uaacaaagcu cccaucgcca aggucaccgg cccuagcaca ggggccgugg     2580

gacgcaauau cgaguucucc ggcaaagacu cuaaggauga agacgggaaa auuguuagcu     2640

acgauuggga cuuuggagac ggcgcuaccu cccgggggaa gaacucugug cacgcguaca     2700

agaaagccgg cacauauaau gucacccuca aggugacgga ugacaaagga gcuacagcca     2760

ccgaaucuuu caccaucgag auuaagaacg aagauacaac cacacccauc acgaaagaga     2820

uggagcccaa ugacgauauu aaggaagcca acggcccuau cguugagggg gugaccguca     2880

agggagaccu gaacggcucc gaugacgcug auacauuuua cuucgacgug aaagaagaug     2940

gggacgugac caucgagcug ccguauucug gaagcuccaa uuuuacaugg cucgucuaca     3000

aggagggcga cgaucagaac cacauugcca gcgggaucga caaaaauaac ucuaagguug     3060

gcaccuucaa auccacgaag ggaagacauu auguguucau uuacaagcac gauagcgcgu     3120

cuaauaucuc cuauagccug aacauuaaag gccuugggaa ugaaaagcug aaagagaagg     3180

aaaacaauga cucuuccgau aaagcuaccg ugauccccaa cuuuaauaca accaugcagg     3240

gaagccuccu gggcgacgau ucccgcgacu acuacagcuu cgaggucaag gaagaggggg     3300

aggugaacau cgaacuggau aagaaagacg aguuuggagu uacauggacc cuucauccug     3360

aaucuaauau uaacgaucgg aucacauaug gccaagugga cggcaauaag gucagcaaca     3420

aagugaagcu cagacccggg aaauacuauc ugcugguuua caaguauucc ggaucuggca     3480

auuacgagcu ccgggugaac aagugaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  6695
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt5)

<400>  6695
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuga agaucauucu caauagaggc aaaaccauga      120

agcggaaaug ccugagcaag cgccuuaugc uggccaucac aauggcuacg auuuuuaccg      180

ugaacuccac acuccccauc uacgccgcgg ucgacaaaaa uaacgcuacc gccgccguuc      240

agaaugaguc uaagagauau acagugagcu accugaagac ccuuaacuau uacgaucugg      300

uggaccuccu ggucaaaaca gaaauugaga aucugccuga ucucuuccaa uauuccucug      360

acgcuaagga auuuuacggg aacaaaaccc ggaugagcuu caucauggau gagaucggac      420

gcagagcccc gcaguauacg gaaauugacc acaagggcau ccccacccug guggagguug      480

ugcgggcugg guuuuaccuu ggauuccaua auaaagagcu gaacgaaauu aauaagcgcu      540

ccuuuaagga gagagucauc ccuucuauuc ucgccaucca gaaaaacccc aauuucaagc      600

ugggcacaga agugcaggau aaaauuguua gcgcgaccgg gcuucuggcc ggaaacgaga      660

cagcuccucc cgaggugguc aauaacuuua ccccuauccu ccaagacugu aucaagaaca      720

uugaucggua cgcccuggac gaucugaaau ccaaggcucu cuucaaugug cuggccgcgc      780

cgacguauga caucacagaa uaccuucgcg ccaccaaaga gaagcccgaa aacacaccuu      840

gguauggcaa gauugauggc uuuaucaaug agcugaaaaa gcucgcucug uacgggaaaa      900

uuaacgacaa uaacagcugg aucaucgaca auggaauuua ucacaucgcu ccccuuggca      960

agcugcauuc uaacaauaaa auugggaucg aaacccucac cgaggugaug aaggucuacc     1020

cuuaucuguc caugcagcac cuucagagcg ccgaucagau uaagagacau uacgacucua     1080

aagaugccga gggaaacaag aucccccucg acaaauucaa gaaagaaggc aaggagaagu     1140

acugcccgaa aacauauacg uuugaugacg ggaagguuau cauuaaagcc ggagcucggg     1200

uggaagagga aaaggugaaa cgccuguacu gggcguccaa ggaggucaau agccaauucu     1260

ucagagugua uggcaucgau aagccucuug aggaaggcaa ccccgacgau auucugacca     1320

ugguuaucua caauucuccu gaggaauaua aacucaacuc cgugcuguac ggguaugaca     1380

caaauaacgg aggcauguac auugagcccg aagggaccuu uuucacauac gagcgggagg     1440

cccaggaaag caccuauacg cuugaggaac uguuucgcca cgaguacaca cacuaucucc     1500

agggaagaua cgcugucccc ggccaguggg ggcggaccaa gcuguaugau aacgacagac     1560

ugaccuggua cgaggaagga ggcgccgaac ucuucgccgg cuccacacgc accucuggga     1620

uccugccucg gaaaagcauu guguccaaua uccauaacac aacgagaaau aaccgcuaua     1680

agcugagcga caccguucac ucuaaauacg gagcuuccuu ugaguucuac aauuaugccu     1740

guauguuuau ggauuacaug uauaacaagg acaugggcau ccugaauaaa cucaacgauc     1800

uggcgaagaa uaacgacgug gauggguacg acaauuauau ucgggaucug agcucuaacu     1860

acgcucuuaa ugacaaguau caagaucaua ugcaggagag aaucgacaac uacgaaaauc     1920

ucacaguccc guucguggcc gaugacuacc ugguccgcca cgccuauaaa aaccccaacg     1980

agauuuacag cgagaucucc gaaguggcua agcugaaaga ugccaagucu gagguuaaaa     2040

agagccagua uuuuuccacc uucacacucc ggggaagcua caccggcggg gcuucuaagg     2100

gcaaacugga agaccaaaag gccaugaaua aauuuauuga cgauucccuu aagaaacugg     2160

acacguauag cuggucugga uacaagaccc ucacagcgua uuucaccaac uacaaggugg     2220

auuccagcaa uagagucaca uacgacgugg uuuuucacgg cuaucugccu aacgaggggg     2280

auuccaaaaa uucucugccc uacggaaaga ucaacggcac cuauaaaggg acggaaaagg     2340

agaaaaucaa guucagcucc gagggaucuu ucgacccuga uggcaagauu gugagcuacg     2400

aaugggacuu uggggauggc aauaaaucca acgaggaaaa ucccgagcau agcuaugaca     2460

aggucggaac auacaccgug aaacuuaagg ugacagauga caaaggcgaa ucuuccguua     2520

gcaccaccac agccgagauc aaggaucucu cugagaacaa acugccgguc auuuauaugc     2580

acgugccuaa guccggggcu cugaaucaga agguggucuu cuacggaaaa ggcacguacg     2640

accccgacgg gagcaucgcc ggauaucagu gggauuuugg cgacgggucu gauuucagcu     2700

ccgaacagaa cccuagccau guguacacca agaaaggcga guauacaguu acccuccgcg     2760

ugauggacuc uuccggacaa augagcgaaa agacaaugaa aauuaagauc accgaucccg     2820

ucuacccuau cggcacggag aaggagccca auaacuccaa agaaacagcu ucugggccga     2880

uugugccugg aauccccguu agcggcacca uugagaauac cuccgaccag gauuauuuuu     2940

acuucgacgu gaucacaccc ggggaaguca agauugauau caacaaacug ggauauggcg     3000

gggccaccug ggugguuuac gacgagaaca auaacgcggu gucuuacgcc acagaugacg     3060

gccagaaucu uagcggaaag uuuaaagcug acaagccugg ccgguauuac auccaccugu     3120

auauguucaa cggguccuac augccguaua gaauuaauau cgaaggaucu gucggccgcu     3180

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  6696
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt5)

<400>  6696
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagagaaaau gccugagcaa gcggcucaug cuggccauca      120

ccauggcuac aauuuucacg gugaacucca cccuucccau cuacgccgcg gucgacaaaa      180

auaacgcuac agccgccguu cagaaugagu cuaagcgcua uaccgugagc uaccugaaaa      240

cacucaacua uuacgaucug guggaccuuc uggucaagac cgaaauugag aaucucccug      300

aucuguuuca auauuccucu gacgcuaagg aguucuacgg caacaaaaca agaaugagcu      360

uuaucaugga ugaaauuggg cggcgcgccc cgcaguauac cgaaaucgac cacaagggaa      420

uccccacgcu gguggagguu gugagagcug gcuucuaccu cggguuucau aauaaagagc      480

ugaacgaaau uaauaagcgg uccuucaaag agcgcgucau cccuucuauu cuugccaucc      540

agaagaaccc caauuuuaag cugggaaccg aagugcagga uaaaauuguu agcgcgacag      600

gccuccuggc cgggaacgag accgcuccuc ccgagguggu caauaacuuc acaccuaucc      660

uucaagacug uauuaagaau aucgauagau acgcccugga cgaucucaaa uccaaggcuc      720

uguuuaacgu gcuggccgcg ccgaccuaug acaucacgga auaccuccgg gccacaaaag      780

agaagcccga aaacaccccu ugguauggaa aaauugaugg cuucaucaau gagcugaaga      840

aacuugcucu guacggcaag auuaacgaca auaacagcug gaucauugac aaugggaucu      900

aucacaucgc uccccucgga aagcugcauu cuaacaauaa aauuggcauc gaaacacuua      960

ccgaggugau gaaggucuac ccuuaucugu ccaugcagca ccuccagagc gccgaucaga     1020

uuaaacgcca uuacgacucu aaggaugccg aggggaacaa gaucccccug gacaaauuua     1080

agaaagaagg aaaggagaaa uacugcccga agaccuauac auucgaugac ggcaagguua     1140

uuaucaaagc cggggcuaga guggaagagg aaaaggugaa acggcuguac ugggcgucca     1200

aggaggucaa uagccaauuu uuccgcgugu auggaaucga uaaaccucuc gaggaaggca     1260

accccgacga uauucugacg augguuaucu acaauucucc ugaggaauau aaacuuaacu     1320

ccgugcugua cggcuaugac accaauaacg ggggaaugua cauugagccc gaaggcacau     1380

ucuuuaccua cgagagagag gcccaggaaa gcacauauac ccucgaggaa cuguuccggc     1440

acgaguacac gcacuaucuu caggggcgcu acgcuguccc cggacagugg ggcagaacaa     1500

agcuguauga uaaugaccgg cucaccuggu acgaggaagg gggagccgag cuguuugccg     1560

gcuccaccag aacaucuggc auccugccuc gcaagagcau uguguccaac auccauaaca     1620

ccacacggaa uaacagauau aagcucagcg acacgguuca cucuaaauac ggggcuuccu     1680

ucgaauuuua caauuaugcc uguauguuca uggauuacau guauaacaag gacaugggca     1740

uucugaauaa acuuaacgau cuggcgaaga auaacgacgu ggauggauac gacaauuaua     1800

uccgcgaucu cagcucuaac uacgcucuga augacaaaua ucaagaucau augcaggagc     1860

ggaucgacaa cuacgaaaau cugaccgucc cguuuguggc cgaugacuac cuugucagac     1920

acgccuauaa gaaccccaau gagauuuaca gcgagaucuc cgaaguggcu aagcucaaag     1980

augccaaguc ugagguuaaa aagagccagu auuucuccac auuuacccug cgcgggagcu     2040

acacaggagg cgcuucuaaa gggaagcugg aagaccaaaa ggccaugaac aaauucauug     2100

acgauucccu caagaaacug gacaccuaua gcuggucugg cuacaagacg cuuaccgcgu     2160

auuuuacaaa cuacaaagug gauuccagca aucgggucac cuacgacgug guuuuccacg     2220

gauaucugcc uaacgagggc gauuccaaaa auucucuccc cuacgggaag aucaacggaa     2280

cauauaaggg caccgaaaag gagaaaauua aguuuagcuc cgaggggucu uucgacccug     2340

auggaaaaau cgugagcuac gaaugggacu ucggcgaugg gaauaagucc aacgaggaaa     2400

aucccgagca uagcuaugac aaggucggca cguacacagu gaaacugaag gugaccgaug     2460

acaaaggaga aucuuccguu agcacaacca ccgccgagau caaggaucug ucugagaaca     2520

aacuuccggu cauuuauaug cacgugccua aguccggcgc ucucaaucag aaaguggucu     2580

uuuacgggaa gggaacauac gaccccgacg gcagcaucgc cggguaucag ugggauuucg     2640

gagacggcuc ugauuuuagc uccgaacaga acccuagcca uguguacacg aagaaagggg     2700

aguauaccgu uacacugaga gugauggacu cuuccggcca aaugagcgaa aagaccauga     2760

aaauuaagau cacagauccc gucuacccua uuggaaccga gaaagagccc aauaacucca     2820

aggaaacggc uucuggcccg aucgugccug ggauccccgu uagcggaaca auugagaaua     2880

ccuccgacca ggauuauuuc uacuuugacg ugaucacccc cggcgaaguc aagauugaua     2940

ucaacaaacu gggguaugga ggcgccacau gggugguuua cgacgagaau aacaacgcgg     3000

ugucuuacgc caccgaugac gggcagaauc ucagcggcaa guucaaagcu gacaagccug     3060

gacgcuauua cauucaccug uauauguuua acggcuccua caugccguau cggaucaaua     3120

ucgaaggguc ugucggaaga ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  6697
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt5)

<400>  6697
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucuccu      120

cugccuacag cguccagaac gaguccaaaa gauauacagu uucuuaccuu aagacgcuga      180

auuauuacga ccucguggau cugcuuguga aaaccgaaau ugagaaccug cccgaccucu      240

uucaauauag cuccgaugcu aaggaguucu acggcaauaa aacacggaug ucuuuuauca      300

uggacgaaau ugggcgcaga gccccucagu auaccgaaau cgaucacaag ggcauuccga      360

cacuggucga ggugguucgg gcgggauucu accugggguu ucauaacaag gagcucaaug      420

aaaucaacaa acgcagcuuc aaggagagag ugauccccuc cauucuggcu auccagaaaa      480

auccuaacuu uaagcuggga accgaagucc aggacaaaau ugugagcgcc acaggccugc      540

ucgccgggaa ugagaccgcu cccccugagg uugugaacaa uuucacgccc auccugcaag      600

auugcauuaa gaacaucgac cgguacgccc uugaugaccu gaagucuaaa gcucucuuua      660

auguccuggc cgcgccuacc uaugauauua cagaauaccu gcgcgccacc aaggagaaac      720

cggaaaacac acccugguau ggaaagaucg acggcuucau caaugagcuc aaaaagcugg      780

cucuuuacgg caaaauuaac gauaacaauu ccuggaucau ugacaacggg aucuaucaca      840

uugccccucu gggaaagcuc cauagcaaua acaagaucgg caucgaaacc cugacggagg      900

ugaugaaagu guaccccuau cuuucuaugc agcaccuuca guccgcugac cagauuaaga      960

gacauuacga uagcaaagac gccgagggga auaagauccc ucucgauaaa uuuaagaagg     1020

aaggaaaaga gaaguacugu cccaaaacau auaccuucga cgauggcaag gucauuauca     1080

aagcgggggc ccggguugaa gaggaaaagg ugaagcgccu guacugggcu ucuaaagagg     1140

ugaacuccca auucuuuaga gucuauggaa uugacaagcc gcuggaggaa ggcaauccug     1200

augacauccu cacaauggug aucuacaaca gccccgagga auauaaacuu aauuccguuc     1260

uuuacggcua ugauaccaac aaugggggaa uguacauuga gccugaaggc accuucuuua     1320

cauacgagcg ggaggcccag gaaucuacgu auacccugga ggaacucuuc cgccacgagu     1380

acacacacua ucugcagggg agauacgcug ugcccggaca guggggccgg accaagcugu     1440

augacaacga ucgccugaca ugguacgagg aagggggagc cgagcucuuu gccggcagca     1500

ccagaacguc cggcauccug ccccggaaaa gcauugucuc uaauauccau aacacaacca     1560

gaaauaaccg cuauaagcug uccgacaccg ugcacagcaa guacggggcu ucuuucgaau     1620

uuuacaacua ugcgugcaug uucauggacu acauguauaa uaaagauaug ggcauucuca     1680

acaagcugaa ugaccuugcc aaaaacaaug auguugacgg auacgauaac uauauccggg     1740

accugagcuc caauuacgcu cucaacgaua aguaucaaga ccauaugcag gagagaauug     1800

auaauuacga aaaccugaca gugccuuuug ucgccgacga uuaccuggug cgccacgccu     1860

auaaaaaucc gaacgagauc uacucugaga ucagcgaagu cgcuaaacuu aaggacgcca     1920

aguccgaggu gaagaaaagc caguauuucu cuaccuuuac acuccggggg uccuacacgg     1980

gaggcgcgag caaggggaaa cuggaagauc aaaaggcuau gaauaaauuc auugacgacu     2040

cucugaagaa gcucgauacc uauuccugga gcggcuacaa aacacugacc gccuauuuua     2100

caaacuacaa gguugacucc ucuaauagag ugaccuacga ugucguguuc cacggauauc     2160

uucccaacga gggcgacagc aaaaacuccc ugccuuacgg gaagaucaau ggaacguaua     2220

aaggcaccga aaaggagaag auuaaauucu cuagcgaggg guccuuugau cccgacggaa     2280

agaucguuag cuacgaaugg gauuucggcg acgggaacaa aucuaaugag gaaaacccug     2340

agcauuccua ugauaaggug ggcacauaca ccgucaaacu caaggugaca gacgauaagg     2400

gagaaagcuc uguguccacc acgacagccg agauuaaaga ccugagcgag aauaagcugc     2460

ccguuaucua uaugcacguc ccgaaaucug gcgcucuuaa ccagaaggug guguuuuacg     2520

ggaaaggaac cuacgauccu gacggcagca ucgccgggua ucagugggac uucggagaug     2580

gcuccgacuu uagcucugaa cagaaucccu cccaugucua cacaaagaaa ggggaguaua     2640

ccgugacccu ccgcguuaug gauagcuccg gccaaauguc ugaaaagaca augaagauua     2700

aaaucacgga cccuguguac cccauuggaa ccgagaagga gccuaacaau agcaaagaaa     2760

cagcuuccgg ccccaucguc ccggggauuc cugugucugg aaccaucgag aacacaagcg     2820

aucaggacua uuucuacuuu gauguuauca cccccggcga agugaagauu gacaucaaua     2880

aacuggggua uggaggcgcc acgugggucg uguacgauga gaacaauaac gcgguuuccu     2940

acgccacaga cgaugggcag aaucugucug gcaaguucaa ggcugacaaa cccggacggu     3000

auuacauuca ccucuauaug uuuaacggca gcuacaugcc uuauagaauc aacauugaag     3060

gguccguggg acgcugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6698
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt5)

<400>  6698
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucuccu      120

cugccuacag caugaaaaga aagugccuuu ccaaacggcu gaugcucgcu auuacaaugg      180

ccacgaucuu uaccgucaac ucuacacugc ccauuuaugc ggcuguugac aagaauaacg      240

ccaccgccgc ucgcagacgg cgcaaaagag ugcagaauga gagcaagcgg uacacagugu      300

ccuaucuuaa gacccugaac uacuaugauc ucgucgaccu gcuggugaaa acagaaaucg      360

agaaucuccc ugaucuguuc caauacucua gcgacgccaa ggaauuuuau ggcaacaaaa      420

cccgcauguc cuucauuaug gaugagaucg ggagacgggc uccgcaguac acggaaaucg      480

accacaaggg cauucccacc cuuguugagg ugguccgcgc cggauuuuac cugggguucc      540

auaauaaaga gcucaacgaa aucaauaaga gauccuuuaa ggagcgggug auuccuucua      600

uccuggcgau ucagaaaaac cccaauuuca aacuuggaac agaaguucag gauaagaucg      660

uguccgccac cggccugcuc gcugggaacg agacagcccc ucccgagguc gugaauaacu      720

uuaccccuau ucugcaagac uguaucaaga auaucgaucg cuaugcucug gacgaucuca      780

aaagcaaggc ccuguucaac gugcuugcgg ccccgacgua cgacauuaca gaauaucuga      840

gagcuaccaa agagaagccc gaaaacacac cuugguacgg aaagaucgau ggcuuuauua      900

augagcucaa aaagcuggcc cuuuauggca aaaucaacga caauaacucu uggauuaucg      960

acaaugggau cuaccacauu gcuccccugg gaaagcucca uuccaacaau aaaaucggca     1020

uugaaacccu gaccgagguc augaagguuu auccuuaccu gagcaugcag caccuccagu     1080

cugccgauca gaucaagcgg cauuacgacu ccaaagaugc cgaggggaac aagauucccc     1140

uggacaaauu caagaaagaa ggaaaggaga aguauugccc gaaaacauac acguucgaug     1200

acggcaaggu gaucaucaaa gcuggggcgc gcguggaaga ggaaaagguc aaaagacuuu     1260

auugggccag caaggaggug aauagccaau uuuuccgggu uuacggaauu gauaagccuc     1320

uggaggaagg caaccccgac gauauccuca ccauggugau uuauaauucu ccugaggaau     1380

acaaacugaa cagcguccuu uauggcuacg acacaaauaa cgggggaaug uacaucgagc     1440

ccgaaggcac cuuuuucaca uaugagagag aggcucagga auccaccuac acgcuggagg     1500

aacucuuucg ccacgaguau acacacuacc ugcaggggcg guaugccgug cccggacagu     1560

ggggcagaac caagcuguac gauaaugacc gccucaccug guaugaggaa gggggagccg     1620

agcuguucgc uggcagcaca cggaccucug gcauucuucc uagaaaaucc aucguuagca     1680

acauucauaa cacaacgcgc aauaaccggu acaagcuguc ugacaccgug cacagcaaau     1740

acggggccuc cuuugaguuc uauaauuacg cguguauguu uauggauuau auguacaaca     1800

aggacauggg aauccucaau aaacugaacg aucuggcuaa gaauaacgac gucgauggcu     1860

augacaauua caucagagau cuuucuagca acuaugcccu caaugacaag uaccaagauc     1920

auaugcagga acgcauugac aacuacgaaa aucugacagu gccguucguc gccgaugacu     1980

aucuggugcg gcacgcuuac aaaaacccca augagaucua uuccgagauu agcgaaguug     2040

ccaagcucaa agaugcuaag ucugagguga aaaaguccca guacuuuagc accuucacac     2100

ugagaggguc uuauaccgga ggcgccucca aggggaaacu ugaagaccaa aaggcgauga     2160

acaaauuuau cgacgauagc cugaagaaac ucgacacgua cuccuggucu ggcuauaaga     2220

cccugacagc cuacuucacc aacuacaagg ucgauagcuc caaucgcgug acauaugacg     2280

uuguguucca cggauaccug ccuaacgagg gcgauucuaa aaauagccuu cccuauggga     2340

agauuaacgg aaccuacaaa ggcacggaaa aggagaaaau caaguuuucc agcgaggggu     2400

cuuucgaccc ugauggaaag aucgucuccu augaauggga cuuuggcgau gggaauaaaa     2460

gcaacgagga aaaucccgag cauucuuacg acaagguggg cacauauacc gugaaacuca     2520

agguuacaga ugacaaagga gaauccagcg ucucuaccac cacagcugag auuaaggauc     2580

ugagcgagaa caaacugccg gugaucuaca ugcacgugcc uaaguccggc gcccucaauc     2640

agaaggucgu guucuacggg aaaggaacgu augaccccga cggcagcauu gcuggguacc     2700

agugggauuu uggagacggc ucugauuucu ccagcgaaca gaacccuucc cauguuuaua     2760

ccaagaaagg ggaguacaca gugacccugc gggucaugga cucuagcggc caaauguccg     2820

aaaagacaau gaaaaucaag auuaccgauc ccguguaucc uaucggaacg gagaaggagc     2880

ccaauaacuc uaaagaaaca gccagcggcc cgaucguucc ugggauuccc guguccggaa     2940

ccaucgagaa uaccucugac caggauuacu uuuauuucga cgucauuaca cccggcgaag     3000

ugaagaucga uauuaacaaa cuuggguacg gaggcgcgac cuggguugug uacgacgaga     3060

auaacaacgc cgucagcuau gcuacagaug acgggcagaa ucuguccggc aaguuuaaag     3120

ccgacaagcc uggaagauac uauauccacc ucuacauguu caacggcagc uauaugccgu     3180

accggaucaa uauugaaggg ucugugggac gcugaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  6699
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt5)

<400>  6699
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcugccu      120

uugcgaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc agcuaugagg      180

ugcugacacc ccucaagugg uaccagucca ucagaccucc cuauccuucu uacggguaug      240

aaccgauggg aggcuggcug caccaucaaa uuauccccgu ccuuagccag cagcacccuc      300

ccacgcauac ccugcagccu caccaccaua uucccguugu gccggcucaa cagccuguga      360

ucccccagca gccuaugaug cccguccccg ggcaacacuc caugacaccu auccagcauc      420

accagccgaa ucugcccccu cccgcccagc aaccuuacca gccccagccg gugcaaccuc      480

agccccacca gccuaugcag ccccaaccuc ccguucaucc gaugcagccu cucccucccc      540

agcccccgcu gcccccuaug uuucccaugc agccucugcc cccuaugcuc cccgaccuua      600

cccuggaggc cuggccgucu acagauaaaa ccaagcggga agagguggac ugaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  6700
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt5)

<400>  6700
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucacc ccucugaagu gguaccaguc cauuagaccu cccuaucccu      180

cuuacggaua ugaaccgaug ggcggguggu gaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  6701
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt5)

<400>  6701
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucaca ccccugaagu gguaccaguc cauuagaccu cccccuaugc      180

uuccggaccu gacccucgaa gccuggcccu cuacggauaa aaccaagcgg gaggaagucg      240

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  6702
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt5)

<400>  6702
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cugcuuagcg      120

gcgcccuggc gcucacacag acgugggcua ugccucugcc gccccacccu gggcaucccg      180

gauacaucaa cuucuccuau gagguucuua ccccucugaa gugguaccaa ucuauucggc      240

ccccuuaucc gagcuacggc uaugaaccca ugggagggug gugaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  6703
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt5)

<400>  6703
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cugcuuagcg      120

gcgcccuggc gcucacacag acgugggcua ugccucugcc gccccacccu gggcaucccg      180

gauacaucaa cuucuccuau gagguucuua ccccucugaa gugguaccaa ucuauucggc      240

ccccuccgau gcuccccgac cugacacugg aagccuggcc uagcaccgau aaaacaaagc      300

gcgaggaagu ggacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  6704
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt5)

<400>  6704
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccucgug ggggcugccu      120

uugcgaugcc ccugccuccg caccccggac auccuggcua cauuaacuuc agcuaugagg      180

uccuuacacc ccugaagugg uaccagucca ugaucagacc ucccuauucu agcuacgggu      240

augaaccuau gggaggcugg cuccaccauc aaauuauccc gguugugucc cagcagcacc      300

cccugacgca uacccuucag ucucaccacc auauuccugu gguccccgcu caacagccuc      360

gggugcgcca gcaggcccug augcccguuc cggggcaaca gagcaugaca ccuacccagc      420

accaucagcc caaucucccu cugcccgccc aacagcccuu ucagccucaa ccggugcagc      480

cccagccuca ccagcccaug caaccucagc ccccggucca gccuaugcag ccccugcucc      540

cucaaccccc ucugcccccg auguucccuc uuagaccccu gcccccuauc cucccggacc      600

ugcaccuuga ggcuuggccc gccacagaua aaaccaagca ggaagaggug gacugaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  6705
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt5)

<400>  6705
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucacc ccucugaagu gguaccaguc caugauuaga ccucccuauu      180

cuagcuacgg auaugaaccc augggcgggu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6706
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt5)

<400>  6706
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucaca ccccugaagu gguaccaguc caugauuaga ccucccccua      180

uccuuccgga ccugcaccuc gaagccuggc ccgcuaccga uaaaacgaag caagaggaag      240

ucgacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6707
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt5)

<400>  6707
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cugcuuagcg      120

gcgcccuggc gcucacacag acgugggcua ugccucugcc gccccacccu gggcaucccg      180

gauacaucaa cuucuccuau gagguucuua ccccucugaa gugguaccaa ucuaugauuc      240

ggcccccuua uagcuccuac ggcuaugaac cgaugggagg guggugagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6708
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt5)

<400>  6708
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cugcuuagcg      120

gcgcccuggc gcucacacag acgugggcua ugccucugcc gccccacccu gggcaucccg      180

gauacaucaa cuucuccuau gagguucuua ccccucugaa gugguaccaa ucuaugauuc      240

ggcccccucc gauccucccc gaccugcacc uggaagccug gccugccaca gauaaaacca      300

agcaggagga aguggacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6709
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt5)

<400>  6709
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcugccu      120

uuagcaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc uccuaugagg      180

ugcugacacc ccucaagugg uaccagaaua ugaucagaca cccuuauacg ucuuacgggu      240

augaacccau gggaggcugg cugcaucacc aaauuauccc ugucguuagc cagcagaccc      300

cgcaguccca ugcgcuucaa ccccaccacc auauuccuau ggugcccgcu cagcagccug      360

ggauccccca gcaaccgaug augccucugc ccggacagca cucuaugaca ccuacccagc      420

aucaccagcc caaccucccc cugccugccc aacagccguu ucagccccaa ccugugcagc      480

cccagccuca ccagccccug caaccgcaga gcccuaugca ucccauccag ccucuccugc      540

cccagccucc ccuuccgccu auguucucca ugcaaucucu gcuccccgac cugccccuug      600

aggccuggcc ugcuacagau aaaaccaagc gggaagaggu cgacugagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6710
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt5)

<400>  6710
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucaca ccccugaagu gguaccagaa uaugauuaga cacccuuaua      180

ccuccuacgg auaugaaccc augggcgggu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6711
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt5)

<400>  6711
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucaca ccccugaagu gguaccagaa uaugauuaga cacccuuccc      180

uucugcccga ccucccucug gaagccuggc cggcuaccga uaaaacgaag cgggaggaag      240

ucgacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6712
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt5)

<400>  6712
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cugcuuagcg      120

gcgcccuggc gcucacacag acgugggcua ugccucugcc gccccacccu gggcaucccg      180

gauacaucaa cuucuccuau gagguucuua ccccucugaa gugguaccaa aauaugauuc      240

ggcaccccua uacaucuuac ggcuaugaac cuaugggagg guggugagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6713
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt5)

<400>  6713
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cucccagaac ccugguccuc cugcuuagcg      120

gcgcccuggc gcucacacag acgugggcua ugccucugcc gccccacccu gggcaucccg      180

gauacaucaa cuucuccuau gagguucuua ccccucugaa gugguaccaa aauaugauuc      240

ggcaccccuc ucuccugccu gaccugccgc ucgaagccug gcccgccaca gauaaaacca      300

agcgcgagga aguggacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6714
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt5)

<400>  6714
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcugccu      120

uuagcaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc uccuauauca      180

gacaccccua cacaucuuau ggguacgagc cuaugggagg cuggcugcau caccagauua      240

uccccguggu cagccaacag acgccucagu cccaugcgcu ccagccgcac caccauauuc      300

ccaugguucc ugcucaacag cccgggaucc cucagcagcc caugaugccg cugccuggac      360

aacacucuau gacccccaca cagcaucacc agccuaaucu uccccugccc gcccagcaac      420

cuuuucagcc gcagcccgug caaccucagc cccaccagcc ucuccagccc caaagcccga      480

ugcauccuau ccagccccug cugccucagc ccccucugcc cccgauguuc uccaugcagu      540

cucuccuucc ugaccugccc cucgaagccu ggcccgcuac cgauaagaca aaacgggagg      600

aaguggacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  6715
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt5)

<400>  6715
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuuugc cugccugcuc ggggcuagcc      120

uggccaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc uccuaugagg      180

ugcugacacc ccucaagugg uaccagaaua ugaucagaca cccuuauacg ucuuacgggu      240

augaacccau gggaggcugg cugcaucacc aaauuauccc ugucguuagc cagcagaccc      300

cgcaguccca ugcgcuucaa ccccaccacc auauuccuau ggugcccgcu cagcagccug      360

ggauccccca gcaaccgaug augccucugc ccggacagca cucuaugaca ccuacccagc      420

aucaccagcc caaccucccc cugccugccc aacagccguu ucagccccaa ccugugcagc      480

cccagccuca ccagccccug caaccgcaga gcccuaugca ucccauccag ccucuccugc      540

cccagccucc ccuuccgccu auguucucca ugcaaucucu gcuccccgac cugccccuug      600

aggccuggcc ugcuacagau aaaaccaagc gggaagaggu cgacugagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6716
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt5)

<400>  6716
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcugccu      120

uuagcaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc uccuaugagg      180

ugcugacacc ccucaagugg uaccagaaua ugaucagaca cccuucucug cuucccgacc      240

ugccucucga agcguggccg gcuacggaua aaaccaagcg ggaggaaguc gacugaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  6717
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt5)

<400>  6717
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcugccu      120

uuagcaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc uccuaugagg      180

accuguaccu cgaagcgauc agaauugauc ggacagcuuu ugugcugacg ccccuuaagu      240

gguaucagaa uaugauccgc cacccuuaca ccucuuaugg guacgagccc augggaggcu      300

ggcugcauca ccaaauuauc ccugucguua gccagcagac accgcagucc caugcccucc      360

aaccccacca ccauaucccu auggugcccg cccagcagcc ugggauuccc cagcaaccga      420

ugaugccucu gcccggacag cacucuauga ccccuacaca gcaucaccag cccaaccugc      480

cccucccugc ucaacagccg uuccagcccc aaccugugca gccccagccu caccagcccc      540

ugcaaccgca gagcccuaug caucccaucc agccucuucu gccccagccu ccccucccgc      600

cuauguuuuc caugcaaucu cugcuucccg accugccccu cgaagccugg ccugcuaccg      660

auaaaacaaa gagagaggaa gucgacugag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  6718
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt5)

<400>  6718
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcugccu      120

uuagcaugcc ccuuccuccg caccccggac auccuggcua cauuaacuuc uccuaugagg      180

ugcugacacc ccucaagugg uaccagaaua ugaucagaca cccuacgccc caaucucaug      240

cgcugcagcc ucaccaucac auuccgaugg uccccgcuca gcagccuggg aucccccaac      300

agccuaugau gccccuuccg ggacagcaca gcaugacccc uacacagcau caccaaccca      360

accugccucu ccccgcccag cagcccuuuc agccucaacc gguucagccc cagccucauc      420

aaccccugca gccucagucc cccaugcacc cgauucagcc ucugcucccc caaccucccc      480

ugccucccau guucucuaug cagagccuuc ugccggaccu cccucuggaa gccuggcccg      540

cuaccgauaa aacaaagcgg gaggaagugg acugaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  6719
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt5)

<400>  6719
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccuc cgcaccccgg ccauccuggg uacaucaacu      120

ucagcuauga ggugcucaca ccccugaagu gguaccagaa uaugauuaga cacccuuaua      180

ccuccuacgg auaugaaccc augggcgggu ggcuucauca ccaaaucauu ccugucguuu      240

cucagcagac gccgcagagc caugcccugc aaccccacca ccauaucccu auggugcccg      300

cucagcagcc uggcauuccc cagcaaccga ugaugccucu ccccggacag cacuccauga      360

ccccuacaca gcaucaccag cccaaccugc cccuuccugc ccaacagccg uuucagcccc      420

aaccugugca gccccagccu caccagcccc ugcaaccgca gucuccuaug caucccaucc      480

agccucuccu gccccagccu ccccugccgc cuauguucag caugcaaucc cuccugcccg      540

accuuccccu ggaggcgugg ccugcuaccg auaaaacaaa gcgggaagag gucgacugag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  6720
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt5)

<400>  6720
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg ccagacugcc ucuccugcuu gggcugcucc      120

ugcuuccgcg gcccggacgc ccucuggacc ucgcugauua caccuaugac cuggccgagg      180

aagaugacag cgagccccug aacuacaagg auccuugcaa agcggcugcc uuccucggcg      240

acaucgcccu ggaugaagag gaccuuagag cuuuucaggu ccaacaggcc guugaucugc      300

ggcgccacac agcuagaaag uccucuauua aagccgcggu gcccgggaau acgagcaccc      360

cuuccuguca gucuacaaac ggacagccgc aacggggcgc cugcgggcgc uggagaggac      420

ggagccgcuc cagacgggcu gccaccucuc gccccgaaag aguguggccu gacggcguca      480

uccccuucgu gauuggcggg aauuuuacag gaagccagcg ggcuguuuuc cgccaggcca      540

ugagacauug ggagaagcac accuguguga cauuucucga gcggaccgau gaagacuccu      600

auaucgucuu cacguacaga ccuugcggcu guugcagcua uguggggcgc cggggaggcg      660

ggccccaggc gauuucuauc ggaaagaacu gugauaaguu uggcaucguu gugcaugagc      720

ugggccacgu cgugggguuc uggcaugaac acaccagacc ggaccgcgac cggcacgugu      780

ccauugucag agagaauauc caaccuggac aggaguacaa cuuucuuaag auggaacccc      840

aggagguuga aagccugggc gagacauaug auuucgacuc uauuaugcau uacgcccgca      900

auaccuuuuc ccgggggauc uuccucgaua caauugugcc uaaauacgaa gugaacggag      960

ucaagccucc caucggccag agaacccgcc ugagcaaagg ggacauugcu caagcccgga     1020

agcuguauaa augccccgcu uguggagaga cgcuccagga uucuacaggc aauuuuucca     1080

gcccggagua ccccaacggc uauuccgccc acaugcauug cguguggaga aucucuguua     1140

ccccugggga aaagaucauu cugaauuuca caagccuuga ccuguaccgc ucccggcucu     1200

guugguauga uuacguggag gucagagacg gauucuggcg gaaggcuccc cugcgcggca     1260

gauuuugcgg gagcaaacuu ccugaaccca ucgugucuac cgauucccgg cuguggguug     1320

aguucagaag cucuagcaac ugggugggaa agggcuuuuu cgccgucuau gaagcgauuu     1380

gcgggggcga cgugaaaaag gauuacggac acauccaguc cccgaauuac ccugacgacu     1440

aucgccccuc uaaagucugu auuuggcgga uccaagugag cgagggcuuu cacguugggc     1500

ucaccuucca guccuuugag aucgaaagac augauagcug cgccuacgac uaucuggagg     1560

ugcgcgaugg acacucugaa uccagcacac ugauuggcag auacuguggg uaugagaagc     1620

cugacgauau caaaucuacg uccagccggc ucuggcugaa guucgucucc gacggaucua     1680

uuaacaaggc uggcuuugcc gugaauuucu uuaaagaagu ugaugagugc agccgcccca     1740

acagaggggg cugugagcag cggugccuua acacccuggg auccuacaag uguucuugcg     1800

acccuggcua ugaacucgcc cccgauaaac gcagauguga ggcugccugc gggggauucc     1860

ugacaaaacu uaauggcagc aucaccuccc cgggguggcc uaaagaauac ccucccaaca     1920

agaauuguau uuggcagcug guggcgccca cacaauaccg gaucagccuc caguuugacu     1980

ucuucgagac cgagggaaac gaugucugca aguaugacuu uguggaagug cgcucuggcc     2040

ugacggcuga uuccaaacug caugggaagu ucugcggcag cgagaaaccg gaaguuauca     2100

caucucagua caauaacaug agagucgagu uuaaguccga caauaccgug agcaaaaagg     2160

gauucaaggc ccacuuuuuc ucugacaaag augaauguag caaggacaac ggcgggugcc     2220

agcaagauug ugugaauacc uuuggauccu augagugcca gugucggagc ggcuucgucc     2280

uccaugacaa caaacacgau ugcaaggagg ccggguguga ccacaaagug acaucuaccu     2340

ccggaacaau uacgagcccc aauuggccug auaaguaccc cuccaagaaa gaaugcaccu     2400

gggcuaucuc uagcacaccu ggccaucgcg uuaagcugac cuuuauggag auggacauug     2460

aaucccagcc cgagugugcc uaugaucacc uugaaguguu cgacgggaga gaugcuaaag     2520

ccccuguccu gggccgguuu ugcggaucua agaaacccga gccggugcuc gcgacaggca     2580

gcagaauguu ccugcgcuuu uacuccgaca acucuguuca gcggaagggg uuccaagcca     2640

gccaugcuac cgagugugga ggccagguga gagccgaugu caaaacgaag gaccuguauu     2700

cccacgcuca guucggggac aauaacuacc cuggaggcgu ggauugcgaa uggguuaucg     2760

uggccgagga aggcuacggg gucgagcuug uguuucagac cuucgaagug gaggaggaaa     2820

cagacugcgg auaugauuac auggagcucu uugacggcua ugauagcacc gcgccccgcc     2880

uggggcggua cuguggaucu ggcccucccg aagaggucua uuccgccggg gacagcguuc     2940

uggugaaguu ccacucugau gacacaauua ccaaaaaggg auuucaucuc agauacacgu     3000

ccacaaaauu ccaagauacc cugcacagcc gcaagugagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  6721
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt5)

<400>  6721
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggca ccagaugccu gcucgcucug cuucugcccc      120

agguccuccu ugggggagcc gcgggccugg uuccugagcu ggggcggcgc aaguucgcug      180

ccgccagcuc cggaagaccg ucuagccaac ccuccgacga agugcucucu gaguuugaac      240

ugcggcugcu cagcauguuc ggccugaaac agcgcccuac acccuccaga gaugcugugg      300

ucccucccua caugcuugac cuguaucggc gccacucugg gcagccugga agcccggccc      360

ccgaucauag acucgagcgg gcugccuccc gcgcgaacac ggugagaucu uuucaccaug      420

aagagucucu ggaggaacuu ccugagaccu ccggcaagac aacccggcgc uucuuuuuca      480

aucugagcuc uauccccaca gaagaguuua uuaccuccgc cgagcuccag guuuucagag      540

aacaaaugca ggacgcucug ggcaacaaua gcucuuuuca ccaucggauc aacauuuacg      600

agaucauuaa accugccaca gcuaauucca aguuccccgu gacccgccug cucgauacga      660

gacuggucaa ccagaaugcc agccgguggg aauccuuuga cgugaccccg gcgguuauga      720

gauggacagc ccaggggcac gcuaaccacg gauucguggu cgagguggcc caucuugaag      780

agaaacaagg cgugucuaag cgccacgucc ggaucagcag aucccugcau caggaugagc      840

acagcugguc ucagauccgc ccucuccugg uuaccuuugg gcacgacgga aagggccauc      900

cccuucacaa acgggaaaag agacaggcua aacauaagca acgcaaacgg cugaagucca      960

gcuguaagag acacccucuc uauguggauu ucucugacgu gggguggaau gauuggauug     1020

ucgccccucc cggauaccau gccuucuauu gccacggcga gugucccuuu ccgcuggcug     1080

accaccugaa cagcacaaau caugcgaucg ugcagacccu cguuaacucc gugaauagca     1140

aaauucccaa ggccugcugu gucccuacgg aacugagcgc uaucuccaug cuuuaccugg     1200

augagaacga aaaagugguu cucaagaauu aucaggacau gguggucgag ggcugcgggu     1260

gucgcugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  6722
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt5)

<400>  6722
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auccccggca acagaaugcu gauggugguc cuccugugcc      120

agguucuucu cgggggagcc agccacgcuu cccugauucc ugagaccggc aagaaaaagg      180

uggccgaaau ccaagggcau gcgggaggcc ggcgcucugg gcagagccac gagcugcuua      240

gagacuucga agcuacacug cuccagaugu uuggacugcg gcgcagaccg cagcccucca      300

aaucugccgu gauuccugau uacaugcggg accuguaucg ccuccaaagc ggcgaggaag      360

aggaggaaca gauccauucc acgggccugg aguaccccga aagaccugcc ucucgggcua      420

auaccguccg cagcuuccac caugaggagc accuugaaaa cauucccggg acauccgaga      480

auagcgccuu uagauuccug uuuaaccucu cuuccauccc ugaaaaugag gugaucagcu      540

cugcugaacu gcggcuuuuc cgcgagcagg uugaucaggg accggacugg gagagaggcu      600

uucaccggau uaacaucuau gaagugauga agcccccugc cgaggucgug cccgggcauc      660

ugauuacccg ccuccuggau acaagacugg uucaccauaa ugugacccgg ugggaaacau      720

ucgacgucuc cccugcggug cucagaugga cccgcgagaa acaacccaac uacggacugg      780

ccaucgaagu gacgcaccuu caccagaccc ggacacauca gggccagcac gucagaauua      840

gccgcucucu gccgcaaggg uccggaaauu gggcucagcu ccggccucug cuuguuaccu      900

uuggccauga uggcagaggg cacgcccuga cacgccggag acgcgcuaag cggagcccca      960

agcaucacuc ccagagagcc cgcaaaaaga acaaaaauug ucggagacac ucucucuaug     1020

uggacuucag cgauguggga uggaacgacu ggaucgucgc gccucccggc uaccaagccu     1080

uuuauugcca uggggauugu cccuucccuc uggcugacca ccucaauucc accaaccaug     1140

ccauugugca gacgcugguu aauagcguga acucuuccau cccgaaggcu ugcugugucc     1200

ccacagagcu gagcgccauc ucuaugcuuu accuggauga guacgacaaa gugguucuca     1260

agaacuauca ggaaauggug gucgagggau gcggcugucg gugaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  6723
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt5)

<400>  6723
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggccugg ggagacgggc ccaguggcuc ugcugguggu      120

ggggacugcu uuguagcugc uguggcccuc cgccccugcg cccuccccuc ccugcugccg      180

cggcugccgc cgcuggggga caacugcuug gcgacggggg aucccccggc agaaccgagc      240

agccuccgcc cucuccucag agcuccucug gcuuccugua ccggcgccuc aagacacagg      300

agaaaagaga aaugcaaaag gaaauccuga gcgugcuggg gcucccccac cggccucgcc      360

cccugcaugg acuucagcag ccgcagccuc ccgcccugag acaacaggag gaacagcagc      420

aacagcagca acucccucgg ggcgagcccc cucccgggcg ccugaaaucc gcuccgcuuu      480

uuaugcugga ucucuauaac gcccugucug cggacaauga ugaggacgga gccagcgaag      540

gcgagagaca gcaguccugg ccccacgaag cugccuccuc uucccagcgg cgccaaccuc      600

ccccuggggc ugcccauccc cugaacagaa agagccuccu ggcgccggga ucuggcuccg      660

gcggggccag cccucuuacg ucugcucagg auuccgccuu ccugaaugac gcugauaugg      720

ucaugagcuu uguuaaccuc guggaguacg acaaagaguu cagcccccgg cagcgccacc      780

auaaggaauu uaaguucaau cugucucaga uuccugaggg agaagugguc accgccgccg      840

aguuuagaau cuauaaagau ugcgugaugg gcagcuucaa gaaccaaaca uuucuuauuu      900

ccaucuacca gguucugcag gaacaccagc accgggacag cgaucucuuc cugcuggaca      960

ccagaguggu cugggcuucu gaggaggggu ggcucgaauu ugauauuaca gcgaccucca     1020

aucugugggu gguuacaccc caacauaaca ugggacuuca gcugagcgug gucacccgcg     1080

acggcgugca cgugcauccu cgggccgcug ggcucgucgg aagagacggc cccuaugaua     1140

aacagccguu caugguugcc uuuuucaagg ugucugaggu gcacguccgc acgacccgga     1200

gcgccuccuc uagacgccgg cagcaaagca gaaaucgcuc cacacagagc caggacgugg     1260

cucggguuuc uuccgccagc gauuacaacu cuuccgaacu gaaaaccgcg uguagaaagc     1320

acgagcuuua ugugagcuuc caagaccugg gcuggcagga uuggaucauc gcuccuaagg     1380

gguacgccgc caauuacugc gacggagaau guuccuuucc ccucaacgcu cauaugaaug     1440

ccacaaacca cgcuauuguc cagacccugg ugcaucugau gaaucccgag uauguuccua     1500

aaccgugcug ugcccccacg aagcucaacg cgaucucugu gcuguacuuc gaugacaaca     1560

gcaaugucau ucuuaaaaag uaucgcaaca uggugguccg ggccugcggc ugucacugag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  6724
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt5)

<400>  6724
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugagaa gccugcgggc cgcugcuccc cauuccuucg      120

ucgcgcucug ggcuccucug uuucuucugc gcucugcccu cgccgacuuc agccuggaua      180

acgagguuca cuccucuuuu auccauagac ggcuucgcag ccaggaaaga cgggagaugc      240

aacgcgaaau ucuguccauc cucggccugc cgcacagacc ccggccucau cugcagggga      300

agcacaauuc ugcucccaug uucaugcucg accuguacaa cgccauggcu guggaggaag      360

gaggcgggcc uggaggccag ggguuuagcu aucccuacaa agccguguuc uccacccagg      420

gaccuccgcu ugcgagccug caagauucuc acuuucucac agacgccgau auggucaugu      480

ccuucgugaa ucugguugag caugacaagg aguuuuucca cccccgcuau caucacagag      540

aauuucgguu cgaucuuagc aaaauuccug agggcgaagc ugugacggcc gcugaguuuc      600

gcaucuacaa ggacuauauu agagagcggu ucgauaacga aaccuuccgc aucucugucu      660

accaggugcu gcaggagcac cucggcagag aauccgaccu guuucugcuc gauagccgga      720

cacugugggc cucugaggaa ggguggcuug uuuucgacau caccgcgaca uccaaucauu      780

ggguggucaa ccccagacac aaucugggac uccagcugag cguggagacc cuugauggcc      840

aauccauuaa cccuaaacug gccgggcuca ucggacgcca uggcccccag aauaagcagc      900

cguuuauggu ggcuuucuuu aaggccacag agguccacuu ccggucuauu agaagcaccg      960

gguccaaaca gcgcagccaa aaccggucua agacgccuaa aaaucaggaa gcucugagaa     1020

uggccaacgu ugccgaaaau uccagcucug accagcgcca agccugcaag aaacaugagc     1080

uguaugugag cuuucgggac cucggauggc aggauuggau cauugcgccc gagggcuacg     1140

ccgcuuacua uugugaaggc gagugcgccu ucccucugaa cuccuacaug aaugccacca     1200

accacgcuau cgugcagaca cuuguccacu uuauuaaccc cgagaccgug cccaagccuu     1260

guugcgcccc gacacagcug aaugcgaucu cuguucucua uuucgacgau agcuccaacg     1320

ugauccugaa gaaauacaga aauauggucg ugcgcgcuug ugggugccau ugaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  6725
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt5)

<400>  6725
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggccagcg cugcccugcu cugccugcuu cugaccgcgg      120

cugccuucuc uccccagggc cucgcccaac cuguggggau caacacaucc acgaccuguu      180

gcuacagauu uauuaauaaa aagaucccga aacagcggcu ggagagcuau cgcagaacaa      240

ccuccucuca cuguccccgg gaagcuguca uuuucaagac aaaacuugac aaggagaucu      300

gcgccgaucc uacccagaag uggguucagg acuuuaugaa acaucuggau aagaaaacac      360

aaacccccaa gcucugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  6726
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt5)

<400>  6726
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucaccc ugaucauucu ucugcccgug gucagcaagu      120

ucuccuuugu uucucucagc gccccucagc acugguccug cccggagggc acacuggcug      180

ggaacggaaa uucuacgugu gugggccccg ccccuuuccu uaucuuuagc caugggaacu      240

ccauuuucag aaucgacacc gaaggaacaa auuacgagca acuggugguc gaugcgggcg      300

ugucuguuau uauggacuuu cacuauaacg aaaaacggau cuacugggug gaucucgagc      360

gccagcugcu gcagagaguc uuccucaaug ggagccggca ggaacgcgug ugcaacaucg      420

agaagaaugu uuccggaaug gcuauuaacu ggaucaauga ggaagugauu uggagcaacc      480

aacaggaggg caucauuacc gucacagaca ugaaaggcaa uaacucucau auccugcuuu      540

ccgcccugaa guaucccgcc aauguggcug uggauccugu cgaaagauuu auuuucugga      600

gcucugaggu ugccgggucc cucuaccggg cugaccugga uggagugggc gugaaagccc      660

uucuggagac cagcgaaaag aucacagcgg ucucucucga cgugcuggau aagcgccugu      720

uuuggaucca guauaacaga gaggggucca auagccucau uuguuccugc gacuacgaug      780

gaggcucugu ucacaucagc aaacauccca cccagcacaa ccuguucgcc augucccuuu      840

uuggggaccg gauuuucuau agcacgugga agaugaaaac caucuggauu gcuaacaagc      900

acacaggaaa agauauggug cgcaucaauc ugcauucuuc cuuugucccu cucggcgaac      960

ugaagguggu ucacccgcuu gcccaaccca aggcugagga cgacaccugg gaaccugagc     1020

agaaacugug uaagcucaga aaaggcaacu gcagcucuac aguguguggg caggaucugc     1080

agagccaucu gugcaugugu gccgagggau acgcgcucuc ccgggaccgc aaguacugcg     1140

aagaugucaa ugagugugcc uucuggaacc acggcugcac ccuggggugc aaaaauacgc     1200

ccggaucuua uuacuguaca ugcccugugg gcuucguccu ucugcccgac gggaagagau     1260

gucaccaacu cgugagcugc ccgcggaacg uuuccgaaug uagccaugau ugcgugcuga     1320

ccucugaggg accucuuugu uuuugccccg aaggcuccgu ccuggagcgc gacggcaaaa     1380

cauguagcgg guguucuucc ccugauaaug gaggcugcag ccagcucugc gugccccugu     1440

cccccguuuc uugggagugc gacuguuucc cuggguauga ucugcagcuc gacgaaaaga     1500

gcugcgcugc cuccggaccg caacccuuuc ugcuuuucgc uaacucucag gauaucagac     1560

acaugcauuu ugacggcacc gacuacggga cccugcucag ccagcagaug ggcauggugu     1620

augcccugga ucacgacccu gucgagaaua agauuuacuu cgcccauaca gcucugaaau     1680

ggaucgaacg ggcgaacaug gauggauccc aaagagagcg ccuuauugaa gagggcgugg     1740

acgugcccga ggggcucgcc guugauugga ucggacggag auuuuauugg acggaccgcg     1800

gcaagagccu gauugggcgg ucugaucuga auggaaaaag auccaagauc aucaccaaag     1860

aaaacauuag ccagccucgc ggcaucgcug uccaccccau ggccaagcgg cuuuucugga     1920

cagacaccgg gauuaauccg agaaucgagu cuuccagccu gcagggccuu ggacgccugg     1980

ugauugccuc uagcgaucuc aucuggccuu ccggcauuac aaucgacuuu cugaccgaua     2040

agcuguacug gugugacgcu aaacagagcg ugaucgaaau ggccaaccuu gaugggucua     2100

agcggagacg ccucacgcaa aaugacgucg gacaccccuu cgcgguggcu guuuuugagg     2160

acuacgugug guucuccgau ugggccaugc cuagcgucau gcgggugaac aaaagaacag     2220

gcaaggaccg gguucgccug caggggucca ugcugaaacc cucuagccuc guggucgugc     2280

auccucuggc caagcccgga gcugauccgu gccuuuauca gaacggcggg ugugagcaca     2340

uuugcaagaa aagacugggc accgccuggu guuccugccg ggaaggauuu augaaggcuu     2400

cugacggcaa aaccugucuc gcccuggaug ggcaucagcu gcuugcggga ggcgagguug     2460

accucaagaa ucaagugaca ccucuggaua uccugagcaa aaccagaguc uccgaagaca     2520

acauuacaga gucucagcac augcucgugg ccgaaaucau ggugagcgau caggacgauu     2580

gcgcucccgu cggguguucc auguacgccc gcugcauuag cgagggagag gacgcuacgu     2640

gccagugucu gaagggcuuc gccggggaug gcaagcucug cucugacauc gacgaaugug     2700

agaugggagu ucccgugugc ccuccggcgu ccagcaaaug uaucaauacc gaaggcgggu     2760

augugugccg guguucugag ggauaccaag gcgaugggau ucacugccug gacaucgaug     2820

aaugucagcu cggagagcau uccugcggcg agaacgccag cuguacaaau accgaaggcg     2880

gguauacaug caugugcgcu ggaagacugu cugagcccgg ccugauuugu ccugacucca     2940

cgcccccucc ccaccuucgc gaagaugacc aucacuacag cgucagaaac uccgauagcg     3000

agugcccucu cucucaugac ggguauuguc ugcacgaugg agugugcaug uacaucgaag     3060

cccuggacaa guacgcuugu aauugcguug ugggcuauau uggggagcgg ugucaguacc     3120

gcgaucucaa auggugggag cugagacacg ccggacaugg ccaacagcag aaggucaucg     3180

ugguugccgu gugcgucgug guucuuguga ugcugcuccu gcugagccuu uggggcgcuc     3240

acuauuaccg gacccagaaa cugcucucca agaaccccaa aaauccguau gaagagucua     3300

gccgcgacgu cagaucccgg cgcccugcgg acaccgaaga ugggaugucu agcugucccc     3360

aaccuugguu cguggugauc aaggagcauc aggaccugaa gaacggaggc cagcccgucg     3420

ccggggagga uggacaggcu gccgacggcu ccaugcaacc gacaucuugg agacaggaac     3480

cucagcucug cgggauggga accgagcagg gcuguuggau ucccguuagc uccgauaaag     3540

gcagcugccc ucaagugaug gaacggucuu uucacaugcc cuccuacggg acacagaccc     3600

uggagggagg cguggaaaag ccccauagcc uucugucugc caauccucuc uggcagcaac     3660

gcgcucugga cccgccccac cagauggagc ugacgcagug aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  6727
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt5)

<400>  6727
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggca gacggaugga gaugcugugc gcugggcgcg      120

ugcccgcccu ccugcuuugu cugggauucc accuccugca ggcgguccuu agcacaacgg      180

uuaucccuuc cugcauuccg ggcgaaucua gcgacaacug uaccgcucug gugcaaacag      240

aggauaaucc cagaguggcc caggucucca ucaccaagug cucuagcgac augaacgggu      300

acugucucca uggacagugc auuuaucugg uggauauguc ccagaauuac ugucggugcg      360

aaguuggcua uacaggggug cgcugugagc acuuuuuccu gaccguccau caaccucucu      420

cuaaagaaua cguggcccug acaguuaucc uuauuauccu guuucucauc accguggucg      480

gaagcacgua uuacuucugc agaugguauc ggaaccgcaa guccaaagag cccaagaaag      540

aguacgaaag agugaccagc ggcgacccug agcugcccca ggugugagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  6728
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt5)

<400>  6728
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgagggcg aaaucaccac auucacggcu cugaccgaga      120

aguuuaaccu gcccccuggg aauuacaaaa agccgaaacu ccuuuauugc agcaacggag      180

gccacuuccu gcggauucuc cccgacggga caguggaugg aaccagagac cgcuccgauc      240

agcauaucca acugcagcuu ucugccgaaa gcgucggcga gguuuacauu aaguccacag      300

aaaccgggca guaucuggcg auggacacag auggacuccu guacggcucu cagaccccua      360

augaggagug ucuguuucuc gaaagacugg aggaaaacca cuauaauacg uacaucagca      420

aaaagcaugc ugagaagaac ugguucgugg gccuuaaaaa gaaugggucc ugcaaacggg      480

gaccccgcac ccacuauggc caaaaggcca uucuguuucu cccucugccc gugucuagcg      540

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  6729
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt5)

<400>  6729
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggcgucg ggggaggcga cguugaggau gugaccccca      120

gaccuggggg augccagauc agcggccgcg gggcccgggg auguaacggc auuccgggcg      180

cugccgcgug ggaagcugcc cugcccagac ggcgcccuag acggcacccc uccgugaauc      240

cucgcucuag agccgcuggg agcccccgga cacgcggaag acggacggag gaacgcccuu      300

ccggcucuag acucggggac cggggacgcg gcagagcccu gcccggggga cggcuuggcg      360

gcagagggcg cggacgggcu cccgagagag ucggcgggcg cggacggggc agagggaccg      420

ccgcgccucg cgccgcuccc gccgcucggg gaagcagacc uggccccgcc ggcacaaugg      480

cggccggguc caucaccaca cugccggcuc ucccugaaga uggaggcucu ggggccuucc      540

cgccuggaca uuuuaaggac cccaaacgcc uguacugcaa gaacggcggg uucuuucuuc      600

ggauucaccc cgauggcaga guggacggag uucgcgagaa aagcgauccu cauaucaagc      660

ugcaacucca ggcugaggaa cggggcgugg ucuccauuaa aggggugugu gccaauagau      720

aucuggccau gaaggaggac ggacggcugc ucgcuagcaa gugcguuacc gaugaauguu      780

ucuuuuucga gcgccuggag ucuaacaauu acaacacaua uagaucccgg aaauacacca      840

gcugguaugu ggcgcuuaag agaacgggcc aguacaaacu ggggucuaag accggaccgg      900

gccagaaagc cauccucuuu cugcccaugu ccgcuaagag cugaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  6730
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt5)

<400>  6730
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uccugaccug gauucucccc acacugcuuu      120

acagaagcug cuuccauauc auuugucugg ugggcacgau cucccucgcc ugcaacgaca      180

ugaccccuga gcagauggcu acaaauguca acuguucuag cccggaacgg cacacccgcu      240

ccuaugauua cauggaaggg ggagacauua gaguucggcg ccuguuuugc agaacacaau      300

gguaucuucg gaucgauaaa cgcggcaagg ugaaagggac ccaggagaug aagaauaacu      360

acaauaucau ggagauuaga acaguggccg ucggaaucgu ggcgauuaaa ggcguugaau      420

cugaguucua ucuggcuaug aacaaggagg ggaagcucua cgccaaaaag gaauguaaug      480

aggacugcaa cuuuaaagaa cugauccugg agaaucauua uaacaccuac gccagcgcua      540

aguggacgca caauggaggc gagauguucg uggcccucaa ccagaaaggc auucccgucc      600

gggggaagaa gaccaaaaag gaacagaaaa cagcucauuu ucugccuaug gccaucaccu      660

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  6731
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt5)

<400>  6731
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugcucc ccagcguggu ccugaaacuu uuccuggccg      120

cuguucucuc cgcccuggug accggcgagu cucuugaaag acugcggcgc gggcucgcgg      180

cuggaacaag caacccugac ccgcccacgg uguccaccga ucagcugcug ccucucggcg      240

ggggaagaga ccggaagguc cgcgaucugc aagaggccga ccuugaucug cucagaguga      300

cacugucuag caaaccccag gcccuugcua ccccuaauaa ggaggaacac ggcaaacgga      360

agaagaaagg gaagggacug ggcaaaaagc gcgaccccug ccucagaaaa uacaaggauu      420

uuuguaucca uggcgaaugc aaguauguua aagagcugcg ggccccuucc uguauuugcc      480

acccggggua ccauggagag cgcugucacg gccugucucu ccccguggaa aacagacugu      540

auacauacga ccauaccaca auccuugcug ucguggccgu ugugcugagc uccgucugcc      600

uccuggugau uguggggcuu cugauguucc gguaucaccg cagaggaggc uacgaugucg      660

agaaugaaga gaagguuaaa cucgggauga ccaacagcca cugaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  6732
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt5)

<400>  6732
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccugcuu cugcagcacg      120

uccuccugca ucuucugcuc cugccuaucg cuauuccgua cgccgagggc caaagaaaac      180

ggcgcaacac aauccacgag uucaagaaaa gcgcgaagac gacccugauu aaaaucgacc      240

ccgcucucaa gauuaagacc aaaaagguua auaccgccga ucagugcgcc aacagaugua      300

cacggaauaa agggcugccu uuuaccugca aggcuuucgu guuugacaaa gcccgcaagc      360

agugucuuug guuccccuuu aacuccaugu cuagcggagu gaagaaagag uucggccaug      420

aauuugaucu guaugagaau aaggacuaca ucagaaacug caucauuggg aaaggacggu      480

ccuauaaggg cacagucucu aucaccaaaa gcgggauuaa gugucagccu ugguccucua      540

ugauccccca cgaacauagc uuccucccuu ccagcuaccg cggaaaagau cugcaagaga      600

auuauugcag aaacccgcgg ggcgaggaag gcgggcccug guguuuuacg ucuaauccug      660

aggugcgcua cgaaguuugc gacauucccc aguguuccga gguggagugc augaccugua      720

acggagaaag cuauagaggc cuuauggauc acacagaguc ugggaagauc ugccagcggu      780

gggaccacca gaccccucau cgccacaagu uccugcccga aagauacccg gauaaaggau      840

uugacgauaa uuacugccgg aacccugacg gccaaccccg cccuuggugu uauacacucg      900

auccccauac aagaugggaa uacugcgcua uuaagacgug ugccgacaau acaaugaacg      960

acaccgaugu cccccuggaa acaaccgagu gcauccaggg gcagggagag ggcuaucggg     1020

gcaccgugaa uacaaucugg aacgggauuc cuugucagag augggacucc caauacccgc     1080

acgaacacga uaugacgccc gagaacuuca aaugcaagga ccugcgcgaa aauuauuguc     1140

ggaacccuga uggaagcgag ucucccuggu gcuuuaccac agacccuaau aucagaguug     1200

gcuacuguuc ccagauuccc aacugcgaua ugagccaugg gcaggacugu uaucgcggaa     1260

auggcaaaaa cuacaugggg aaucucuccc aaacccgguc uggacugaca ugcagcaugu     1320

gggauaagaa cauggaagac cuucacagac auaucuucug ggagccggau gcguccaagc     1380

ugaaugagaa cuacugccgc aauccugacg acgaugccca cggccccugg uguuauaccg     1440

gcaacccucu cauucccugg gacuacugcc cuaucagccg gugugaaggg gauacgacac     1500

ccaccaucgu gaaucuggac cauccgguca uuucuugcgc uaaaaccaag cagcuuagag     1560

uggugaacgg aaucccuaca cgcaccaaua uuggcuggau ggucucccug cgguauagaa     1620

acaaacacau cuguggggga agccucauua aggagucuug gguucugaca gcccgccagu     1680

gcuuccccag ccgggaucug aaagacuacg aggcuuggcu cggcauccac gaugugcaug     1740

ggagaggcga cgaaaagugu aaacaggugc ugaacgucuc ccaacuugug uauggacccg     1800

aaggcucuga ucugguucuc augaagcugg cccggccugc ggugcuugac gauuuuguca     1860

gcacgaucga ccugccgaau uacgggugca ccauucccga gaagacaucc uguagcgugu     1920

auggaugggg cuacaccggg cucaucaacu acgauggacu gcugcgcguu gcccaccucu     1980

auauuauggg caaugagaaa ugcucucagc aucacagagg gaaggugaca cugaacgaau     2040

ccgagaucug ugcuggcgcc gagaaaauug gaagcggccc uugcgaaggg gacuacggag     2100

gcccccuugu cugcgagcag cacaagaugc ggauggugcu gggggucauc gugccuggaa     2160

gaggcugugc uauucccaau cgcccuggga ucuucguucg gguggccuau uacgccaagu     2220

ggauccauaa aauuauccuc accuauaagg ucccccaguc uugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  6733
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt5)

<400>  6733
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggcug ccgcgaucgg cauugaccug gggaccacau      120

acagcugcgu gggagucuuc cagcacggca aaguugagau cauugcuaac gaucaaggga      180

auagaacgac ccccuccuau guggccuuua cagacaccga acggcucauc ggagaugccg      240

cuaagaacca gguggcccug aauccucaga acacagucuu cgacgcuaaa cgccuuauug      300

gcagaaaguu uggggauccg gugguucagu cugacaugaa acauuggccc uuccaaguga      360

ucaaugaugg agacaagccu aagguccagg ugagcuacaa aggcgagacc aaggccuuuu      420

aucccgaaga gaucuccucu augguucuga caaaaaugaa ggaaauugcg gaggccuacc      480

ucggcuaucc ugugaccaac gcugucauca cggugcccgc cuacuucaau gauagccagc      540

ggcaggcuac caaagacgcc ggggugauug cgggacugaa cguccuucgc aucauuaaug      600

agccuacagc cgcugccauc gcuuauggcc uggauagaac cgggaaggga gaacggaacg      660

uucucauuuu ugaccugggc gggggaacau ucgauguguc cauccugacc aucgacgacg      720

gcauuuuuga ggugaaggcc acggccggcg auacacaccu cgggggagaa gacuucgaua      780

aucgccuggu caaccauuuu guggaggagu ucaaaagaaa gcacaaaaag gacaucucuc      840

aaaauaaacg ggcuguucgc agacuucgga ccgcguguga acgcgccaag agaacacuga      900

gcuccagcac ccaggcuucu cucgagauug auucccuguu ugaaggcauc gacuucuaca      960

ccagcauuac acgggcccgc uucgaggaac uuugcucuga ucuguuuaga uccacgcucg     1020

agccggugga gaaagcccug cgggacgcua agcuggauaa ggcccagauc caugaccucg     1080

uccugguugg gggaagcacc agaaucccca aagugcagaa acuucugcaa gauuucuuua     1140

acggccgcga ccucaauaag ucuauuaacc cugacgaagc gguggcuuac ggggccgccg     1200

uccaggcugc cauccugaug ggagauaagu ccgagaacgu gcaggaccuu cugcuccugg     1260

augucgcucc ccugagccuc ggccuggaaa cagccggcgg ggugaugacc gcgcuuauua     1320

aacggaauag cacaaucccu accaagcaaa cgcagauuuu cacaaccuau ucugacaacc     1380

agcccggagu ucugauccag guguacgagg gcgaaagagc caugaccaag gauaauaacc     1440

uccuggggcg cuuugagcuu agcggaaucc cgccugcucc ccggggcguc ccucaaauug     1500

aggugacauu cgacaucgau gccaauggga uucugaacgu uaccgcuaca gacaaaucca     1560

cgggcaaggc caauaaaauc accauuacaa acgauaaggg aagacucagc aaagaagaga     1620

ucgaacgcau ggugcaggag gcggaaaagu auaaggccga ggacgagguc cagcgggaaa     1680

gagugucugc uaaaaaugcc cuggaguccu acgcuuuuaa caugaagucc gccguggaag     1740

augagggccu gaaagggaag auuucugagg ccgacaaaaa gaagguucuc gauaaauguc     1800

aggaagucau cagcuggcug gacgcuaaua cccuugcgga gaaggacgag uucgaacaca     1860

aacgcaagga acuggagcaa gugugcaacc ccaucauuuc cggacucuau cagggcgccg     1920

ggggacccgg cccugggggc uuuggagcuc agggcccgaa agggggaucu ggcagcgggc     1980

ccacaaucga ggaaguggau ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6734
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt5)

<400>  6734
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggcug ccgcgaucgg cauugaccug gggaccacau      120

acagcugcgu gggagucuuc cagcacggca aaguugagau cauugcuaac gaucaaggga      180

auagaacgac ccccuccuau guggccuuua cagacaccga acggcucauc ggagaugccg      240

cuaagaacca gguggcccug aauccucaga acacagucuu cgacgcuaaa cgccuuauug      300

gcagaaaguu uggggauccg gugguucagu cugacaugaa acauuggccc uuccaaguga      360

ucaaugaugg agacaagccu aagguccagg ugagcuacaa aggcgagacc aaggccuuuu      420

aucccgaaga gaucuccucu augguucuga caaaaaugaa ggaaauugcg gaggccuacc      480

ucggcuaucc ugugaccaac gcugucauca cggugcccgc cuacuucaau gauagccagc      540

ggcaggcuac caaagacgcc ggggugauug cgggacugaa cguccuucgc aucauuaaug      600

agccuacagc cgcugccauc gcuuauggcc uggauagaac cgggaaggga gaacggaacg      660

uucucauuuu ugaccugggc gggggaacau ucgauguguc cauccugacc aucgacgacg      720

gcauuuuuga ggugaaggcc acggccggcg auacacaccu cgggggagaa gacuucgaua      780

aucgccuggu caaccauuuu guggaggagu ucaaaagaaa gcacaaaaag gacaucucuc      840

aaaauaaacg ggcuguucgc agacuucgga ccgcguguga acgcgccaag agaacacuga      900

gcuccagcac ccaggcuucu cucgagauug auucccuguu ugaaggcauc gacuucuaca      960

ccagcauuac acgggcccgc uucgaggaac uuugcucuga ucuguuuaga uccacgcucg     1020

agccggugga gaaagcccug cgggacgcua agcuggauaa ggcccagauc caugaccucg     1080

uccugguugg gggaagcacc agaaucccca aagugcagaa acuucugcaa gauuucuuua     1140

acggccgcga ccucaauaag ucuauuaacc cugacgaagc gguggcuuac ggggccgccg     1200

uccaggcugc cauccugaug ggagauaagu ccgagaacgu gcaggaccuu cugcuccugg     1260

augucgcucc ccugagccuc ggccuggaaa cagccggcgg ggugaugacc gcgcuuauua     1320

aacggaauag cacaaucccu accaagcaaa cgcagauuuu cacaaccuau ucugacaacc     1380

agcccggagu ucugauccag guguacgagg gcgaaagagc caugaccaag gauaauaacc     1440

uccuggggcg cuuugagcuu agcggaaucc cgccugcucc ccggggcguc ccucaaauug     1500

aggugacauu cgacaucgau gccaauggga uucugaacgu uaccgcuaca gacaaaucca     1560

cgggcaaggc caauaaaauc accauuacaa acgauaaggg aagacucagc aaagaagaga     1620

ucgaacgcau ggugcaggag gcggaaaagu auaaggccga ggacgagguc cagcgggaaa     1680

gagugucugc uaaaaaugcc cuggaguccu acgcuuuuaa caugaagucc gccguggaag     1740

augagggccu gaaagggaag auuucugagg ccgacaaaaa gaagguucuc gauaaauguc     1800

aggaagucau cagcuggcug gacgcuaaua cccuugcgga gaaggacgag uucgaacaca     1860

aacgcaagga acuggagcaa gugugcaacc ccaucauuuc cggacucuau cagggcgccg     1920

ggggacccgg cccugggggc uuuggagcuc agggcccgaa agggggaucu ggcagcgggc     1980

ccacaaucga ggaaguggau ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6735
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt5)

<400>  6735
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaccgcua agggcaucgc cauugggauc gaccugggaa      120

caacguacag cugcgugggc gucuuccagc acgggaaggu ugagauuauc gcgaacgauc      180

aaggaaauag aaccacaccc uccuaugugg cuuuuaccga cacagaacgg cucauuggcg      240

augccgccaa gaaccaggug gcuaugaauc cucagaacac cgucuucgac gccaaacgcc      300

ugaucgggag aaaguuuaau gauccggugg uucaggcuga caugaaacuu uggcccuucc      360

aagugaucaa cgagggaggc aagccuaagg uccugguguc uuacaaaggc gaaaauaagg      420

ccuuuuaucc cgaggaaauu agcuccaugg uucucacaaa acugaaggag accgcggagg      480

ccuuccuugg gcauccugug acgaacgcug ucaucaccgu gcccgccuac uuuaaugauu      540

cucagcggca ggcuacaaaa gacgccggag ugauugcggg ccugaacguc cuccgcauca      600

uuaaugaacc uaccgccgcu gccaucgcuu augggcugga uaagggaggc cagggggaga      660

gacacguucu gauuuucgac cucggaggcg gcacauuuga ugugagcauc cugaccaucg      720

acgaugggau uuucgaagug aaggccacgg ccggagacac acaucuuggc ggggaggacu      780

uugauaaccg gcuggucucc cacuucgugg aggaauuuaa acgcaagcau aaaaaggaca      840

ucucucaaaa uaaaagagcu guucggcgcc ucagaaccgc gugugagcgg gccaagcgca      900

cacugagcuc cagcacccag gcuaaccuug aaauugauuc ucuguacgag ggaaucgacu      960

ucuauaccuc cauuacaaga gcccgguucg aggaacucug cgccgaucug uuucgcggca     1020

cgcuggagcc gguggaaaaa gcucucagag acgccaagau ggauaaggcg aaaauccacg     1080

acaucguccu gguuggggga agcacccgga uucccaaggu gcagagacuu cugcaggauu     1140

acuucaaugg ccgcgaccuc aacaaaucua ucaacccuga ugaggcugug gccuacggcg     1200

ccgcugucca agccgcuauu cugauggggg acaaguccga aaaagugcag gaccuucugc     1260

uccuggaugu cgcgccccug agccucggac uggagacagc cggcggggug augaccgccc     1320

uuaucaagcg gaauagcaca auuccuacca agcagacgca aaucuuuaca accuauuccg     1380

acaaccagcc cggaguucug auccaggugu acgaaggcga gagagcuaug accaaagaua     1440

auaaccuccu ggggcgcuuc gaccuuacag gcauuccgcc ugcuccccgg ggagucccuc     1500

agaucgaggu gaccuuugau auugacgcca auggcauccu gaacguuaca gccacggaua     1560

agagcaccgg gaaagugaau aagauuacaa ucaccaacga caaaggaaga cucuccaagg     1620

aagagauuga acgcaugguc cuggaugcgg agaaguauaa agccgaagac gaggugcaac     1680

gggagaagau cgcugccaaa aaugcucugg aaucuuacgc cuucaacaug aagucugugg     1740

uuuccgauga gggccucaaa gggaagauca gcgaaucuga caagaauaaa auucuggaua     1800

aguguaacga gcuucugucc uggcucgagg ucaaucagcu ggccgaaaaa gacgaguuug     1860

accacaagag aaaagaacug gagcagaugu gcaaccccau cauuacaaaa cuuuaucagg     1920

gaggcuguac cgggcccgcu ugcggcacgg gauacgugcc uggccgcccg gcgaccgggc     1980

ccacaaucga agagguggau ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6736
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt5)

<400>  6736
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgccagag gccccgcuau cgggauugac cugggaacca      120

cauacuccug cgugggcguc uuccagcacg ggaagguuga gaucauugcc aacgaucaag      180

gaaaucggac gaccccuucu uauguggcgu uuacagacac cgaacgccuc aucggcgaug      240

cugccaaaaa ccagguggcc augaauccga caaacaccau uuucgacgcu aagagacuga      300

ucgggcggaa auuugaggau gccacagucc agagcgacau gaagcauugg cccuuccgcg      360

ugguuuccga aggaggcaaa ccuaaggugc aggucgagua caagggcgaa accaaaacgu      420

uuuuccccga ggagaucucu agcauggugc uuaccaagau gaaagaaauu gcugaggccu      480

aucugggagg aaagguucac uccgcgguga ucacaguccc ugccuacuuu aaugauucuc      540

aaagacaggc uaccaaagac gccggcacaa uuaccgggcu caacgugcug cggaucauua      600

augaacccac ggcugccgcg aucgccuaug gacuugauaa gaagggcugu gcugggggag      660

agaaaaacgu gcugauuuuc gaccucggcg gcgggacauu ugaugucagc auccugacca      720

ucgaggacgg aauuuucgaa guuaagucca cagccggcga uacccaucuu gggggagagg      780

acuuugacaa ucgcauggug agccaccucg cugaagaguu caaaagaaag cauaaaaagg      840

auaucggccc uaacaaacgg gccgugcgca gacugcggac cgccugcgaa cgcgcuaaga      900

gaacacuuuc uuccagcacg caggcgucua uugagaucga cucccuguac gagggggucg      960

auuuuuauac cagcauuaca cgggcccgcu ucgaggaacu caaugcugac cuguucagag     1020

gaacccuuga accgguggag aaggcccugc gggaugccaa acucgacaag ggccagaucc     1080

aagaaaucgu ucuggugggc gggucuacac gcauucccaa aauccagaag cugcuccagg     1140

acuuuuucaa cggaaaagag cugaauaagu ccauuaaccc ugaugaggcu gucgccuacg     1200

gcgcggcugu gcaggccgcc auccuuauug gggauaagag cgaaaauguu caagaccugc     1260

uccugcuuga ugugacgccc cugucccucg gaaucgagac cgcuggcggg gucaugacac     1320

cucugaucaa aagaaacacc accauuccca caaagcagac ccagacauuu acgaccuacu     1380

cugacaacca aagcuccgug cugguccagg uguaugaagg cgagcgggcc augacaaaag     1440

acaauaaccu ccugggaaag uucgaucuua ccggcauccc gccugcuccc agagggguuc     1500

cucagauuga agugacauuu gacaucgaug ccaaugggau ucugaacguc accgcggccg     1560

acaaaagcac gggcaaggag aauaagauca ccauuacaaa cgauaaaggg cgccucucua     1620

aggacgauau cgaccggaug gugcaggagg cugaaagaua caaauccgag gaugaagcca     1680

aucgcgaccg gguugcugcc aagaacgcgc uggagagcua uaccuacaau aucaaacaaa     1740

caguggagga ugaaaagcug agaggaaaga uuucugagca ggacaaaaac aagauccugg     1800

auaaauguca ggaagucauu aauuggcucg accgcaacca gauggccgag aaggacgaau     1860

augagcacaa acaaaaggag cuggaacggg ugugcaaucc caucauuagc aaacuguacc     1920

agggcgggcc cggcggaggc uccgggggag gcgggucugg agcuagcggc gggccuacca     1980

ucgaggaagu ggauugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  6737
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt5)

<400>  6737
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccag uccugcuacg      120

uugccguggc uagagccgga ggcauugaga ccaucgcgaa cgaauauucu gaucggugua      180

cacccgcuug cauuagcuuu gggccuaaga aucgcuccau cggagccgcc gcuaaaucuc      240

aagugauuag caacgccaag aauacggucc agggcuucaa aagauuucac gggcgggcuu      300

ucuccgaccc guuuguggag gccgaaaagu cuaaccucgc guacgauauc guucagcugc      360

ccaccggacu uacaggcauc aaagugaccu auauggagga agaacgcaau uucacaaccg      420

agcaggucac agccaugcug cucagcaagc ugaaggaaac cgcugagucc gugcuuaaaa      480

agccuguugu ggacuguguc gugagcgugc ccugcuuuua cacggaugcc gaaagacggu      540

cugucaugga cgcuacccaa auugccggcc ugaacugucu ccgccugaug aaugagacaa      600

ccgcgguugc ccuggcuuau gggaucuaca aacaggaucu cccugcccug gaggaaaagc      660

ccagaaacgu gguguucguc gacaugggac auuccgcuua ucaggugagc guuugcgccu      720

uuaaucgggg caaacuuaag gugcuggcca cagcuuucga uaccacgcuc gggggacgca      780

aguuugacga gguccuggug aaccacuucu gugaagaguu uggcaaaaag uacaaacuug      840

auauuaaguc uaaaaucaga gcgcugcucc ggcuguccca ggaaugcgag aagcugaaaa      900

agcucaugag cgccaaugcu ucugaccugc cucuuuccau ugaguguuuc augaacgaug      960

uugacgugag cgggacaaug aaucgcggaa aguuccugga aaugugcaac gaccuccugg     1020

ccagagucga gccgccccuu cgguccgugc uggaacaaac caaacucaag aaagaggaua     1080

ucuacgccgu cgaaauugug ggcggcgcua cacgcauccc ugccguuaag gagaaaaucu     1140

cuaaguuuuu cgggaaggag cugagcacca cccugaaugc ggacgaagcu gugacaagag     1200

gaugugcccu ccagugcgcc auucuguccc ccgcuuuuaa aguccgggag uucagcauca     1260

cggauguggu uccuuauccc auuucucuua gauggaacuc cccggccgaa gagggcagcu     1320

cugacugcga aguguuuagc aagaaccaug cugccccuuu cuccaaaguc cugaccuuuu     1380

accgcaagga gcccuucaca cucgaggcgu auuacucuag cccucaggau cugcccuauc     1440

ccgacccugc caucgcucag uuuuccgugc aaaaagugac cccgcagagc gaugggucuu     1500

ccagcaaggu uaaggucaaa gugcggguga auguccacgg aauuuucucu guguccagcg     1560

ccucccuugu ugaagugcau aagucugagg aaaacgagga gcccauggaa acagaccaga     1620

augcuaaaga ggaagagaag augcaagucg aucaggagga gccucacgug gaggaacagc     1680

agcaacagac ccccgccgag aacaaagcgg aaagcgagga aauggagacg ucccaggccg     1740

gcucuaagga caagaaaaug gaucagccuc cccaagcuaa gaaagccaag guuaaaacaa     1800

gcaccgugga ccugccgauc gagaaucagc uccuguggca gaucgacaga gaaaugcuga     1860

accucuacau ugagaaugaa gggaagauga ucaugcagga uaaacuggag aaggaacgca     1920

acgacgcuaa gaaugccguc gaggaguaug uguacgaaau gcgggauaaa cuuuccggag     1980

aguacgaaaa guuuguuagc gaggacgaua gaaacucuuu cacccugaaa cucgaggaca     2040

cagaaaauug gcuguaugag gauggcgaag accaaccuaa acagguguac gucgauaagc     2100

uggccgagcu uaagaaccuc ggccagccca uuaagauccg cuuucaggaa uccgaggagc     2160

ggccuaaacu guucgaggaa cuggggaagc aaauucagca guauaugaaa aucaucagcu     2220

cuuucaagaa uaaagaagac caauacgauc accucgacgc ugcggauaug accaaggugg     2280

agaaguccac aaacgaagcc auggagugga ugaauaacaa acugaaccuu cagaauaagc     2340

agagccugac gauggacccc guggucaaau cuaaggagau ugaagcuaaa aucaaggagc     2400

ucaccagcac auguuccccu auuaucagca agcccaaacc gaagguugaa ccucccaaag     2460

aggaacagaa gaacgccgag caaaauggac ccguggacgg ccagggggau aacccuggac     2520

cgcaggccgc ugagcagggc accgacacag ccgugcccuc ugauuccgac aaaaagcugc     2580

cugaaaugga uauugacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  6738
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt5)

<400>  6738
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccuc aacugcuaca      120

uugccguugc uagauccgga ggcaucgaga ccauugccaa ugaauauucu gaucggugua      180

cacccgcgug caucagccug gggucccgca cgagagcuau uggaaacgcc gccaagucuc      240

agaucgugac caaugugcgg aacacaaucc acggcuuuaa aaagcugcau gggcgcagcu      300

ucgacgaucc uauuguccaa accgagagaa uccggcuucc guacgaacuc cagaaaaugc      360

ccaauggauc cgcuggcgug aagguucgcu aucuggagga agagagaccu uuugccauug      420

aacaggugac aggcaugcuu cuggcuaaac ucaaggagac cucugagaac gcccugaaga      480

aacccgucgc ggacugugug aucagcauuc cuuccuucuu uacagaugcc gaacggcgca      540

gcguuauggc ugccgcucag guggccgggc ugaauugccu cagacugaug aacgagacca      600

cggcggucgc ccuugcuuac ggaaucuaua agcaagaccu gcccccucuc gaugagaaac      660

cgcggaaugu gguguucauu gacaugggcc acucugccua ccagguccug guuugugcuu      720

uuaacaaggg gaaacuuaag gugcuggcca ccacauucga ucccuaucuc ggaggccgca      780

auuuugacga agcccuggug gauuacuucu gcgacgaguu uaagaccaaa uacaagauca      840

acgucaaaga aaauuccaga gcucugcucc ggcuguauca ggagugugaa aaacuuaaga      900

agcugaugag cgcgaacgcc ucugaucucc cucugaauau cgagugcuuc augaacgacc      960

uugacguguc cagcaaaaug aaccgcgcuc aguuugagca acugugugcc ucucuccugg     1020

ccagaguuga acccccucug aaggcuguga uggagcaggc caaucuccag cgggaagaua     1080

uuuccagcau cgagauuguc gggggagcga caagaauccc cgcugugaag gaacagauua     1140

ccaaauucuu ccugaaggac aucuccacga cacuuaacgc cgaugaggcc guugcucgcg     1200

gcugcgcccu gcaaugugcu auccucucuc cggccuuuaa agugcgggag uucagcauua     1260

ccgaccuggu cccuuacucc aucacacuua gauggaagac cagcuuugaa gauggcucug     1320

gggagugcga aguguucugc aaaaaucauc ccgcgccuuu uuccaagguc auuaccuucc     1380

acaagaaaga gcccuuugaa cuggaggccu ucuauacaaa ccuccaugag gugcccuacc     1440

cugacgcucg caucggcagc uuuacgauuc agaauguuuu cccgcagucu gauggagaca     1500

gcuccaaggu gaaagucaag gugcggguua acauccacgg gaucuuuucu guggccagcg     1560

cuuccgucau ugaaaaacaa aaucuggagg gagaucacag cgacgccccc auggaaaccg     1620

agacaucuuu caagaacgag aauaaggaua acauggacaa aaugcaagug gaccaggaag     1680

agggccauca gaagugucac gcggaacaua ccccugagga agagaucgau cacacagggg     1740

ccaaaaccaa guccgcugug agcgacaaac aggauagacu gaaucagacg cucaagaagg     1800

gaaaaguuaa gucuauugac cugcccaucc aguccagccu uugccgccag cugggccaag     1860

aucuccugaa cuccuauauu gagaaugaag gcaaaaugau caugcaggac aagcuggaga     1920

aagaacggaa cgaugccaag aaugcugucg aggaauacgu guaugacuuu agagaucgcc     1980

uugggacagu guacgagaaa uucauuaccc cugaggaccu cucuaagcug agcgccgucc     2040

uggaagauac cgagaacugg cucuacgaag acggagagga ucagcccaaa cagguguaug     2100

uugacaagcu gcaagaacuu aagaaauacg gccagccgau ccagaugaag uauauggagc     2160

acgaggaacg gccuaaagcc cugaacgacc ucgggaagaa gauccagcug gugaugaaag     2220

ucauugaggc uuacagaaau aaggaugaac gcuaugacca ucuggauccc acagagaugg     2280

agaaagugga aaaguguauc uccgacgcga ugucuuggcu uaacagcaaa augaaugccc     2340

aaaacaagcu cucccugacc caggauccug uugugaaggu cagcgagauu guggcuaaau     2400

cuaaggaacu ggacaauuuc ugcaacccca ucauuuacaa accuaagccc aaagccgagg     2460

uuccggaaga uaagccuaag gccaauuccg agcacaacgg acccauggac ggccagagcg     2520

ggacagagac gaaaucugau uccaccaagg acagcucuca acauacaaaa agcuccggcg     2580

aaauggaggu ggauugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  6739
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt5)

<400>  6739
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugagcc ucguggccgc uaugcugcuu cugcucuccg      120

ccgcgagagc ugaggaagag gacaaaaagg aagaugucgg caccguugug gggaucgacc      180

ugggaacaac guacucuugc gugggcgucu ucaaaaacgg gcggguggag auuaucgcca      240

augaucaggg aaaccgcauu acccccagcu auguugccuu uacaccugaa ggcgagagac      300

uuaucgggga cgcugccaag aaucaacuga ccuccaaccc ggagaauaca guguucgaug      360

cuaaacggcu cauuggacgc accuggaacg accccucugu ccagcaggau aucaaguuuc      420

ugccuuucaa ggugguugaa aagaagacaa aacccuacau ccagguggac auuggcggcg      480

ggcaaaccaa gacguuugcc ccugaggaaa ucagcgcgau gguccugacc aaaaugaagg      540

agacagccga ggcuuaucuc ggaaagaaag ugacccacgc cguggucaca guucccgcuu      600

acuucaauga ugcccagaga caggcgacca aggacgccgg cacgauugcu gggcugaacg      660

ugaugcggau cauuaaugaa ccuacagccg cugccaucgc cuauggacuu gauaaacgcg      720

agggcgaaaa gaacauucug guguuugacc ucgggggagg caccuucgau gucucccugc      780

uuacaaucga caauggcgug uuugagguug uggcuaccaa cggggacacc caucugggag      840

gcgaagauuu cgaccagaga gucauggagc acuuuaucaa acucuacaag aaaaagacag      900

ggaaggaugu gcggaaagac aaucgcgcgg uucaaaagcu gagacgggag guggaaaaag      960

ccaagcgcgc ucugucuagc cagcaucagg ccagaauuga gaucgaaucc uucuaugagg     1020

gagaagauuu uagcgagacg cucacccggg ccaaauucga ggaacugaac auggaccuuu     1080

uccgcucuac aaugaagccg guccagaagg ugcuggagga uuccgaccuc aaaaagagcg     1140

auauugacga aaucguccug gugggcgggu cuacccggau ucccaaaauc caacagcuug     1200

uuaaggaguu uuucaaugga aaagaaccuu ccagaggcau caaccccgau gaggcugugg     1260

ccuacggcgc ggcuguccag gccggggugc ugagcggaga ccaagacaca ggcgaucucg     1320

uucugcugga cguguguccu cucacccugg ggauugagac ggucggaggc gugaugacaa     1380

aacuuauccc cagaaacacc gugguuccga ccaagaaauc ucagaucuuu uccacagcca     1440

gcgauaauca gccuaccguc acaauuaagg uguacgaagg ggagcgcccc cugacgaaag     1500

acaaccaccu ccugggcacc uucgaucuua caggcauucc ucccgcuccc cggggagugc     1560

cucagaucga agucaccuuu gagaucgacg ugaaugggau ucugagaguu acagccgagg     1620

auaagggaac cggcaacaaa aauaagauca cgauuaccaa cgaccaaaau cgccucacac     1680

cggaagagau cgaacggaug gugaacgaug cugagaaguu cgccgaagag gacaaaaagc     1740

ugaaagagag aauugauacc cgcaaugaac uggaguccua ugcguacucu cucaagaacc     1800

agaucgggga caaagaaaag cugggaggca aacuuagcuc cgaggauaag gaaacaaugg     1860

agaaggccgu cgaggagaaa auugaauggc uggaaagcca ucaggacgcu gacaucgagg     1920

auuuuaaggc caaaaagaaa gaacucgagg agaucgugca gcccauuauc ucuaagcugu     1980

auggguccgc uggcccuccc ccuaccggag aagaggacac ggccgaaaag gaugagcugu     2040

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  6740
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt5)

<400>  6740
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gagagcuggc ugugggcauc gaccucggga      120

ccacauacag cugcgucgga guuuuccaac agggccgggu ggaaauucug gccaacgauc      180

aggggaaucg cacgaccccu uccuaugugg cguuuacaga caccgagaga cuugucggag      240

augcugccaa gucucaggcc gcucugaacc cgcacaauac aguguucgac gccaaacggc      300

ucaucggccg caaguuugcu gauaccacag uucaaagcga caugaaacau uggcccuuca      360

gaguggucuc cgaaggggga aagccuaaag ugcggguuug uuaccgcggc gaggauaaga      420

ccuuuuaucc cgaagagauu ucuagcaugg ugcuguccaa gaugaaagag acggccgaag      480

cguaccuugg ccagccuguc aagcacgccg ugaucaccgu gcccgcuuau uucaacgacu      540

cucagagaca ggccacaaaa gaugcugggg ccauugcggg acugaauguc cuccggauca      600

ucaacgagcc uaccgccgcu gccauugcuu acggccugga ccgcagaggg gccggagaac      660

ggaauguucu gaucuuugau cucggcgggg gaacauucga cgugagcgug cuguccauug      720

augccggcgu cuuugaggug aaggcuaccg cgggcgacac gcaucuuggg ggagaggacu      780

ucgauaaccg ccugguuaau cacuuuaugg aagaguucag acggaaacau ggcaaggacc      840

ucagcgggaa caagcgcgcc cugagacggc uuagaacagc uugcgaacgc gccaaacgga      900

cccugucuuc cagcacacaa gccacccucg agaucgauuc ucuguuugaa ggaguggacu      960

ucuauaccuc cauuacaaga gcucgcuucg aggagcugug uagcgaucuc uuucggucua     1020

cgcuggaacc ggucgagaag gcccuuagag acgcgaaacu ggauaaggcu cagauccacg     1080

acgugguucu cgugggcggg uccacccgca uucccaaagu ccagaagcug cuucaggauu     1140

ucuuuaaugg aaaagaacug aacaagagca ucaauccuga cgaggccgug gccuacggcg     1200

cugccgucca agcugccgug cucaugggcg auaagugcga aaaaguucag gaccugcugc     1260

uccuggacgu ggcgccccuu ucccuggggc ucgagacagc cggaggcguc augaccacac     1320

ugauccagcg gaacgcuacc auuccuacga agcaaacaca gaccuucacc acauacucug     1380

auaaucagcc cgggguguuu auccagguuu augagggaga aagagccaug accaaagaca     1440

acaaccuucu gggccgcuuc gagcucagcg ggauuccgcc ugcuccccgg ggcgugccuc     1500

aaaucgaagu cacauuugau auugacgcca auggaauccu guccgugacg gcgaccgaua     1560

gaagcacagg caaggccaac aaaaucacca uuacaaauga caaggggcgc cugucuaagg     1620

aggaagugga gcggaugguu cacgaggcug aacaguacaa agccgaggau gaagcucaga     1680

gagaccgggu cgccgccaag aacucccucg aggcucaugu guuccacgug aaaggaagcc     1740

ugcaggagga aucucuucgc gauaagaucc ccgaggaaga cagacggaaa augcaagaua     1800

aguguagaga gguccuggcg uggcucgaac auaaucagcu ggccgagaag gaggaauaug     1860

agcaccagaa acgcgaacug gagcagauuu gccggcccau cuuuagcaga cuuuacggcg     1920

ggccuggagu gccgggcggg uccucuugug gcacccaagc ucgccaggga gaccccagca     1980

cgggcccuau uaucgaagag guugauugag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  6741
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt5)

<400>  6741
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gagagcuggc ugugggcauc gaccucggga      120

ccacauacag cugcgucgga guuuuccaac agggccgggu ggaaauucug gccaacgauc      180

aggggaaucg cacgaccccu uccuaugugg cguuuacaga caccgagaga cuugucggag      240

augcugccaa gucucaggcc gcucugaacc cgcacaauac aguguucgac gccaaacggc      300

ucaucggccg caaguuugcu gauaccacag uucaaagcga caugaaacau uggcccuucc      360

agguggucuc cgaaggggga aagccuaaag ugagaguuug uuaccggggc gaggauaaga      420

ccuuuuaucc cgaagagauu ucuagcaugg ugcuguccaa gaugaaagag acggccgaag      480

cguaccuugg ccagccuguc aagcacgccg ugaucaccgu gcccacauau uucucuaaca      540

gccagcgcca agcuaccaaa gacgccgggg cuauugccgg acugaagguc cucccuauca      600

ucaaugaggc gacagccgcu gccauugcuu acggccugga uagacgcggg gccggaaaac      660

ggaacguucu gaucuuugac cucggcgggg gaaccuucga uguguccgug cugagcauug      720

acgccggcgu cuuugaagug aaggcuacgg cgggcgauac acaucuuggg ggagaggacu      780

ucgacaauag acugguuaac cacuuuaugg aggaguuccg gcgcaagcau ggcaaagauc      840

ucucugggaa uaagagagcc cugcggcgcc uuagaaccgc uugcgagcgg gccaaaagaa      900

caccguccag cucuacccag gccacccugg aaaucgacuc ccucuuugag ggaguggauu      960

ucuauaagag cauuacacgc gcucgguucg aagaacugug uucugaccug uuuagaucca     1020

cgcucgagcc cgucgaaaaa gcccugcgcg augcgaaacu ugacaaggcu cagauccacg     1080

auuucgugcu gggcggggga cuccacagcc auccucaggg cgccgagguu gccgcuggcc     1140

ugcuucaacg gcagggggcc gaacaggagc accaacccug aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  6742
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt5)

<400>  6742
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaagggcc ccgccguggg gaucgaccug ggaaccacau      120

acuccugcgu cggcguuuuc cagcacggga aaguggagau uaucgcuaac gaucaaggaa      180

auagaacgac cccuucuuau guggccuuua cagacaccga acggcucauu ggcgaugcgg      240

cuaagaacca ggucgccaug aauccgacaa acaccguguu cgacgccaaa cgccugaucg      300

ggagacgguu ugaugacgcu guugugcaga gcgauaugaa gcauuggccc uucauggucg      360

ugaaugacgc cggacgcccu aaaguucagg uggaguacaa gggcgaaaca aaguccuuuu      420

aucccgagga agucucuagc auggugcuua ccaaaaugaa ggagauugcu gaggccuacc      480

ugggcaaaac ggugaccaac gcggucguua cagugccugc cuauuucaau gauucccaaa      540

gacaggcuac caaggacgcc gggacaaucg cuggacucaa cgugcugcgg aucauuaaug      600

aacccaccgc cgcggccauc gcuuacggcc uugauaaaaa ggucggggcc gagcgcaacg      660

ugcugauuuu ugaccucgga ggcgggacgu ucgauguuuc uauccugaca auugaagacg      720

gaaucuuuga ggugaagucu accgcuggcg acacacaccu gggcggggag gauuucgaca      780

auagaauggu caaccauuuu auugccgaau uuaaacggaa gcacaaaaag gauaucuccg      840

agaauaaacg cgccgugaga cggcuccgca ccgcuuguga aagagcgaag cggacccuga      900

gcagcuccac acaggccagc aucgagauug acucucuuua ugaaggaauc gauuuuuaca      960

cguccauuac ccgcgcuaga uucgaggagc ugaacgccga ccucuuccgg ggcacacugg     1020

auccuguuga aaaagcccuu agagacgcua agcuggauaa gagccagauc caugacauug     1080

ugcucgucgg gggaucuacc cgcaucccga aaauccaaaa gcugcugcag gauuucuuca     1140

auggcaaaga gcucaacaag uccauuaacc ccgacgaagc cguggcguac ggggcugccg     1200

uccaggccgc uauccugagc ggagacaaau ccgagaaugu gcaggaucuu cugcuccugg     1260

acguuacacc ucuuucucug ggcauugaaa ccgccggcgg ggugaugacg guccucauca     1320

agcggaacac aaccauuccc accaagcaaa cacagaccuu uacaacguau agcgauaauc     1380

agccuggagu gcugauccaa guuuacgagg gcgagagagc uaugaccaaa gacaacaauc     1440

ugcucgggaa guucgaacug acaggaaucc cgcccgcccc ucgcggcgug ccccagauug     1500

aggucaccuu ugauaucgac gcgaacggga uucuuaaugu guccgccgug gauaaaagca     1560

caggcaagga aaacaaaauc accauuacga augacaaggg acggcugucu aaggaggaua     1620

ucgaaagaau gguucaggag gcugagaaau auaaggccga agacgagaaa cagcgcgaua     1680

aggucuccag caaaaacucu cucgaaagcu acgcuuucaa uaugaaggcc accguggagg     1740

acgagaagcu gcaaggcaaa auuaacgaug aagacaagca gaaaauccuu gacaagugca     1800

augagaucau uaacuggcug gauaaaaauc agacagcgga aaaggaggaa uuugagcacc     1860

agcaaaaaga gcucgaaaag guguguaacc cuaucauuac caagcuguau caguccgccg     1920

ggggaaugcc cggcgggaug cccggaggcu ucccuggggg cggagcuccg cccucuggcg     1980

gggccagcuc cggaccuaca aucgaggaag ucgacugagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  6743
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt5)

<400>  6743
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucagcgccu ccagagcugc cgcggcucgg cuggugggcg      120

ccgccgcuuc ucgcgggccc accgccgcua gacaccagga cagcuggaac ggacucuccc      180

augaggccuu ccggcugguc ucucgcagag auuacgcgag cgaagccauu aagggcgcug      240

uuguggggau cgaccuugga acaacgaaua gcugcguggc cgucauggag ggcaaacaag      300

cuaaggugcu ggaaaacgcc gagggggcgc ggaccacacc uucuguugug gccuuuaccg      360

cugauggaga acgccucguc ggcaugccgg ccaaaagaca ggcugugaca aaucccaaca      420

auaccuucua ugccacaaag cggcugauug gccgcagaua cgacgauccu gagguucaga      480

aagacaucaa gaacgugccc uuuaagauug uccgggccag caauggggau gcuugggugg      540

aggcgcacgg aaaacuuuau uccccuagcc agaucggcgc cuucgugcug augaagauga      600

aagaaaccgc ugagaacuac cucgggcaua cggccaagaa ugccgucauc accguucccg      660

cuuauuuuaa cgacucucaa cgccaggcca caaaagaugc gggacagauu uccggccuga      720

augugcugag agugaucaac gaaccuaccg cugccgcccu cgcuuacggg cuggacaaga      780

gcgaggauaa ggucauugcc guguaugacc uuggaggcgg cacauucgau aucucuauuc      840

uggagaucca gaaagggguu uuugaaguga aguccaccaa uggagacacg uuccucggcg      900

gggaggacuu ugaucaagcu cugcuucggc acauugucaa agaguucaag cgcgaaacag      960

gaguggaccu gaccaaagau aacauggccc uccagagagu ucgggaagcg gccgagaagg     1020

cuaaauguga gcuguccucu uccgugcaga cagacaucaa ucugccguac cucaccaugg     1080

auagcuccgg ccccaagcau cugaacauga aacuuaccag agcccaguuu gaagggaucg     1140

ucacagaccu gauucgccgg acgaucgcuc cuugccaaaa ggccaugcag gaugcggagg     1200

ugucuaagag cgacauugga gaagucaucc ucgugggcgg caugaccaga augcccaaag     1260

uucagcaaac agugcaggau cuguucgggc gcgccccuuc caaggcuguc aaccccgacg     1320

aggccguggc uauuggagcc gccauccagg gcgggguucu ugcuggagau gugaccgacg     1380

uccugcuccu ggacgugaca ccgcugagcc ucggcaucga aacccugggc ggcguguuua     1440

cgaaacuuau uaaucggaac acaaccaucc cuaccaagaa gucucagguu uucuccacag     1500

cggccgaugg acaaacccag gucgagauua aaguguguca gggcgagaga gaaauggcug     1560

gggacaauaa gcugcucgga caguucacac ugaucggcau ucccccugcu ccccgcgggg     1620

ugccccaaau cgaggucacg uuugauaucg acgccaacgg aauugugcac guuagcgcca     1680

aagauaaggg caccgggcgg gaacagcaga ucgugauuca gucuagcggc ggacuuucca     1740

aagacgauau cgagaauaug gucaagaacg ccgaaaagua cgcggaggag gacagacgca     1800

aaaaggaacg gguggaggcu guuaauaugg ccgaaggcau uauccacgau acagagacca     1860

aaauggagga guucaaggac caacugccug ccgaugaaug caacaaacuc aaggaagaga     1920

uuucuaagau gagagaacug cuggcucgca aagacagcga gacaggggag aauauccggc     1980

aggccgcguc cagccuccag caggcuucuc ugaaacuuuu ugaaauggcc uauaagaaga     2040

uggccuccga gagagaagga agcgggucuu ccgggaccgg agagcaaaaa gaagaucaga     2100

aggaggagaa acagugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  6744
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt5)

<400>  6744
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg aggcuggcgg gagcgaugga cccagagaaa      120

ccgccccuac auccgcguac ucuagcccgg cucggucccu gggcgacacg gggaucacac      180

cccucucucc uagccacauu gugaacgaua ccgacuccaa ugucucugag cagcagagcu      240

uccugguugu gguggccguc gauuuuggaa ccacauccag cggcuaugcc uacucuuuca      300

ccaaagaacc cgagugcauc caugugaugc gcagauggga agggggagac ccuggcguuu      360

ccaaccaaaa gacacccacc acgauucuuc ugaccccuga gcggaaauuu cacagcuucg      420

gcuaugcugc ccgcgauuuu uaccaugacc ucgauccgaa ugaggcuaag caguggcugu      480

aucuugaaaa auucaagaug aagcugcaca caaccgggga ccucacaaug gauaccgacc      540

ugacggccgc gaacggcaaa aaggugaaag cccuggagau cuuugcuuac gcccuccagu      600

auuucaagga acaagcucug aaagagcuuu cugaucaggc cggauccgag uuugaaaaua      660

gcgacgucag augggugauu acaguucccg cgaucuggaa gcagccugcc aagcaguuca      720

ugcggcaagc ugccuaccag gcugggcugg ccucucccga gaacuccgaa cagcucauca      780

uugcccugga gccugaagcu gcgagcaucu acugucgcaa acuuagacug caucagauga      840

uugagcucuc cucuaaggcc gcugugaaug gauauagcgg cuccgacacc gucggggccg      900

gauuuacaca agccaaagag cacauccggc gcaacagaca gagccggacc uuccuggugg      960

aaaaugugau uggcgagauc uggucugaac uggaggaagg cgauaaguac gucguugugg     1020

acuccggggg aggcaccgug gaucucacag uccaccagau ucgccugccc gaggggcauc     1080

uuaaagagcu guauaaggcu acgggaggcc cguacgggag ccucggagug gacuaugaau     1140

uugagaaacu gcuuuacaag aucuucggcg aagauuucau cgagcaauuu aagauuaaaa     1200

gaccugccgc guggguugac cugaugaucg cuuucgaauc ucggaagcgc gccgccgcuc     1260

ccgauagaac caacccucuc aauauuacac ugcccuuuag cuucaucgac uauuacaaaa     1320

aguuucgggg ccacuccgug gagcaugccc ugagaaaauc uaacgucgau uucgugaagu     1380

ggagcuccca ggggaugcuc cgcaugagcc ccgacgcuau gaaugcccug uuuaagccua     1440

ccauugauuc uaucaucgag caccuucggg accuguucca gaaaccggaa guuuccacag     1500

ugaaguuucu cuuccugguc ggaggcuuug cggaggcucc ccuucugcag caagccgugc     1560

aggccgcuuu cggggaccag ugcagaauua ucauuccuca ggaugucgga cucaccaucc     1620

ugaaaggcgc cgugcuguuu gggcucgacc ccgcgguuau uaaggugcgc cggagcccuc     1680

ugacguacgg cgucggagug cuuaacagau auguugaagg caaacauccc ccggagaagc     1740

ugcucgugaa ggaugggaca cgcuggugua ccgacgucuu cgauaaauuc aucucugccg     1800

accaauccgu ggcucuggga gagcugguga agcggagcua caccccugcc aaacccuccc     1860

agcuuguuau cgucauuaau aucuauucua gcgaacacga uaacgugucc uuuauuacag     1920

acccuggcgu gaagaaaugc gggacccuca gacuggaucu gacaggaacg ucuggcaccg     1980

cuguccccgc ccgccgggag auccagacac ucaugcaguu cggggacacc gaaauuaagg     2040

ccacagcuau cgauauugcg accagcaagu ccgugaaagu uggcaucgac uuucugaacu     2100

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  6745
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt5)

<400>  6745
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuggccgugc ccgagauggg ccuccagggg cuguacaucg      120

gaagcucccc ugaaagaucu ccggucccca gcccucccgg cuccccucgg acccaagagu      180

cuugcgggau ugcuccccuu acaccuagcc aguccccgaa gcccgaaguu cgcgccccuc      240

agcaggcguc uuucagcgug guggucgcua ucgacuuugg aacgaccucc agcggcuaug      300

ccuucucuuu ugccuccgau cccgaggcua uucacaugau gagaaaaugg gaagggggag      360

acccuggcgu ggcccaucaa aagacaccca ccugucugcu ccugacaccg gagggcgcuu      420

uccacagcuu uggguacacc gcccgggauu auuaccauga ccuugauccu gaggaagcgc      480

gcgacuggcu guauuucgag aaauuuaaga ugaaaaucca cucugccaca gaucucaccc      540

ugaagacgca gcuggaagcu guuaacggaa agaccaugcc cgcccucgag guguucgcuc      600

augcccugag auuuuuccgg gagcacgcgc uucaggaacu gcgcgagcag uccccuagcc      660

uccccgaaaa agacacaguc agaugggugc ugaccguucc cgccauuugg aagcaaccug      720

cuaaacaguu uaugcgggag gccgcuuacc uugccggccu ggugucucgc gaaaaugccg      780

agcagcuccu gaucgcucug gagccggaag cggccuccgu cuauugcaga aagcuccggc      840

ugcaccagcu ucuggaucuc agcgggcgcg cucccggagg cgggagacug ggagagcggc      900

gcuccaucga cucuagcuuc agacaagccc gggaacagcu uagacgcucc cggcauagca      960

gaacauuucu gguggagucu ggcgugggcg aacucugggc cgagaugcag gcuggggauc     1020

gcuacgucgu ugccgacugu ggaggcggga ccguggaucu gacggugcac caacuggagc     1080

agccucaugg aacacucaaa gaacuguaca aggcguccgg cgggcccuau ggagcugucg     1140

gcguggaccu ugccuucgag cagcugcucu gccggauuuu cggcgaagac uuuaucgcca     1200

ccuucaagag acagcgcccu gcugccuggg uugaucugac aauugcuuuu gaggcccgga     1260

aaagaaccgc ggggccccac cgcgccggag cucuuaacau cagccugccg uucucuuuua     1320

uugacuucua ccggaagcaa agaggccaca auguggaaac cgcccuccgc cggagcuccg     1380

ucaacuuugu gaaauggucu agccagggga ugcugagaau guccugugag gcuaugaaug     1440

agcuguucca gccuacaguu agcggaauca uucagcauau cgaagcccuc cuggcgcggc     1500

ccgaggugca aggcgucaaa cuucuguuuc ucgucggggg cuucgccgaa ucugcugugc     1560

ugcagcacgc cgugcaggcu gcccugggag cccgcggccu uagaguugug gucccucaug     1620

auguggggcu cacgauccug aagggagcug uucuguuugg ccaggcgccc gggguggucc     1680

gggugagacg cuccccucuc accuauggag ugggcguucu gaaccgguuc guccccggga     1740

gacacccgcc ugagaaacuu cuggugcgcg acggcagacg guggugcaca gauguguuug     1800

agcgcuucgu cgccgcugaa caaagcgugg cccucggaga ggaaguuaga cggucuuacu     1860

gucccgcccg ccccggccag agacgggugc ugauuaaucu guauugcugu gcugccgagg     1920

acgcgcgcuu caucaccgau ccugggguca gaaagugcgg agcucuuucc cucgaacugg     1980

agccggccga cuguggccag gauacagccg gggcuccccc uggacggcgc gagauuagag     2040

ccgcgaugca guuuggcgac accgaaauca aggugacggc uguugaugug agcacaaacc     2100

gguccgucag agccucuauu gacuuccuga gcaauugagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  6746
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt5)

<400>  6746
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagagaga ugaccauccu gggcagcgcu gugcucacac      120

ugcuucuggc cggguaccuc gcgcagcaau aucugccccu uccuacgccg aaggucauug      180

gaaucgaccu gggcaccaca uacugcuccg uugggguguu cuuucccgga accggcaaag      240

ugaaggucau uccugaugaa aacgggcaca ucucuauucc cagcauggug uccuucacag      300

acaaugaugu uuauguggga uacgagucug ucgaacucgc ugacagcaac ccucagaaua      360

ccaucuauga ugccaaacgg uuuaucggca agauuuucac agccgaggaa cuggaggcug      420

agaucggccg cuaccccuuu aaagugcuga acaagaaugg gaugguugag uucuccguga      480

ccucuaacga aacgauuacc gucagcccug aauauguggg auccagacuc cugcuuaagc      540

ugaaagagau ggccgaggcu uaccucggca ugccgguggc caaugcgguc aucagcguuc      600

ccgccgaauu ugaccugaag cagcggaacu cuacaauuga ggcugccaau cuugcugggc      660

ugaaaauccu ccgcgugauu aacgaaccua ccgccgcggc cauggcuuac ggacugcaua      720

aggccgaugu guuccacguc cuggugaucg accucggcgg gggaacacug gauguuuccc      780

uucugaauaa acagggcggc auguuucuca ccagagcuau gagcgggaac aauaagcugg      840

gaggccaaga cuucaaccag cggcuucugc aguaucucua caagcagauc uaucaaacgu      900

acggguuugu gcccucucgc aaagaggaaa uucauagacu gcggcaggcc gucgagaugg      960

ugaagcugaa ucucacacug caccaguccg cccagcuuag cguucugcuc accguggagg     1020

aacaagaucg caaagagccu cauucuuccg acacagaacu gcccaaggau aaacuuagcu     1080

ccgcugacga ccacagaguc aacucuggau ucggccgggg gcugagcgau aagaaauccg     1140

gagagagcca ggugcucuuu gaaaccgaga ucucucgcaa gcuguucgac acccugaacg     1200

aggaucucuu ccagaagauu cuggucccga uccaacaggu gcuuaaagaa ggccaccugg     1260

agaagacaga aauugacgag guugugcucg ucggcggguc cacgagaauc ccucggaucc     1320

gccaggugau ucaggaauuu uucggaaaag aucccaauac cagcguugac ccugaucugg     1380

cgguggucac aggcguggcc auccaagcug ggauugacgg aggcucuugg ccccuucagg     1440

ugagcgcccu ggagaucccc aacaagcauc uccagaaaac caauuuuaac ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6747
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt5)

<400>  6747
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgcuaucg gcguccaccu ggggugcacc agcgccugug      120

ucgcgguuua caaggacggc agagcuggag ugguggccaa cgaugccggg gaccggguca      180

cacccgcugu gguugccuau uccgagaaug aagagauugu gggacucgcu gccaaacagu      240

cucgcaucag aaacauuagc aauacgguca ugaaggugaa acaaauccug ggccgguccu      300

cuagcgaucc ucaggcgcag aaguacauug ccgaauccaa augccuuguu aucgagaaga      360

acgggaagcu gcgcuaugaa aucgacaccg gagaggagac aaaauucgug aauccggaag      420

augucgcuag acucaucuuu ucuaagauga aagagaccgc ccauagcgug cugggcuccg      480

acgcuaacga uguggucauu acaguucccu ucgacuuugg cgaaaagcag aaaaaugccc      540

uuggggaggc ggcccgggcu gccggauuca acgugcugcg ccucauucac gagccuagcg      600

cugcccugcu ggccuacggc aucgggcaag auucucccac cggaaagucc aauauucucg      660

uguuuaagcu gggcgggaca agccuuucuc uguccgucau ggaagugaac agcggaaucu      720

auagaguucu cucuaccaau acggacgaua acauuggcgg cgcucauuuc accgagacac      780

uggcgcagua ccuugccucc gaauuucagc ggagcuucaa acacgacgug cgcgggaaug      840

cuagagccau gaugaagcug accaacuccg ccgaggucgc uaaacauucu cucagcacac      900

ugggauccgc caauuguuuu cuggauagcc ucuaugaagg ccaggacuuc gacugcaacg      960

ugucucgggc gcgcuuugag cugcuuuguu ccccucuguu caacaagugc aucgaggcua     1020

ucagagggcu ccuggaucaa aauggauuua ccgccgacga uauuaacaaa guugugcuuu     1080

guggcgggag cucucggauc cccaagcugc agcagcucau uaaagaccug uucccugccg     1140

ucgaacugcu caauagcauc ccgcccgaug aggugauucc uaucggagcu gccaucgaag     1200

cuggcauucu gaucggcaag gagaaccuuc uggucgaaga cucccucaug auugagugcu     1260

cugcccgcga uauccuggug aaggggguug acgagagcgg agcguccaga uucacggugc     1320

uuuuucccag cggcacaccu cugcccgccc ggagacagca cacccuccaa gcuccggggu     1380

cuauuuccag cgucugucug gaacuguacg agucugaugg caaaaauucc gccaaggaag     1440

agacaaaauu cgcucaggug guucuccagg accuggauaa gaaagaaaac ggacuucgcg     1500

acauccuggc cgugcucacc augaagcggg acgggagccu gcacgugacc ugcacagauc     1560

aagagacggg caagugugag gcgaucucca uugaaaucgc cucuugagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  6748
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt5)

<400>  6748
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gccuggacgu ugggucccag ucuugcuaca      120

ucgccguggc uagagccgga ggcauugaga ccaucgcgaa cgaauuuagc gaucggugua      180

cacccuccgu gauuucuuuu gggagcaaga aucgcacgau cggagucgcu gccaaaaacc      240

aacagauuac ccacgccaau aacacagugu ccaauuucaa gagauuucau ggccgggcuu      300

ucaacgaccc uuuuauccag aaagagaagg aaaaucucuc uuaugaucug guuccgcuua      360

aaaacggggg agugggcauc aaggucaugu acaugggcga ggaacaccug uucagcgugg      420

agcagauuac cgccaugcuc cugacaaaac uuaaagagac cgcugaaaau ucccugaaga      480

aacccguuac agacugcgug aucagcgucc cuucuuucuu caccgaugcc gagcgcagau      540

ccgugcucga cgcggcccaa auuguggggc ugaacugucu gcggcucaug aaugauauga      600

cggcugucgc ccugaacuau ggaaucuaca agcaggaccu ucccagccug gaugaaaaac      660

cucgcauugu uguguuugug gacaugggcc auucugcuuu ccaggucucc gccugcgcgu      720

uuaauaaggg gaagcucaaa gugcugggaa ccgccuucga ucccuuucuu ggcgggaaga      780

acuucgacga gaaacugguu gagcacuucu gugcugaauu uaagacaaaa uauaagcucg      840

augccaaaag caagaucaga gcucugcugc ggcucuacca ggagugcgaa aagcugaaaa      900

agcugauguc uuccaauagc accgaccuuc cucucaacau ugaguguuuc augaacgaca      960

aagauguguc cggaaagaug aaucgcucuc aauuugagga acugugcgcc gagcuucugc     1020

agaaaaucga agucccgcuc uauagccugc uggagcagac acaucucaag guggaagacg     1080

uuuccgccgu ggagaucguc ggcggcgcua cccggauucc cgcggugaag gaaagaaucg     1140

ccaaauucuu ugggaaggau auuagcacga cacugaacgc ugacgaggcc gucgcccgcg     1200

gaugugcccu ucagugcgcu auccugucuc cugcguucaa agugagagag uuuuccguua     1260

ccgaugcugu gcccuucccu auuagccuca ucuggaauca cgacucugaa gauacagagg     1320

gcguccacga aguguuuagc cggaaccaug ccgcccccuu cuccaagguu cugaccuuuc     1380

uucgcagagg gccguucgag cuggaggcuu uuuacucuga cccucaagga gugcccuacc     1440

cugaagccaa aaucggccgg uucgucgugc agaaugugag cgcucagaag gauggggaga     1500

aguccagagu uaaagucaag gugcgcguga acacccacgg aauuuucaca aucagcacgg     1560

ccucuauggu cgaaaaagug cccaccgagg aaaaugagau guccagcgag gcggacaugg     1620

aaugucucaa ccaacggccc ccugagaauc cggauacaga caagaacguu cagcaggaca     1680

auucugaagc cggcacccag ccccaagugc agacagaugc ucagcagacc ucccaaagcc     1740

cucccucccc ugagcugacg ucugaagaga acaaaauucc cgacgccgau aaggcuaaug     1800

agaagaaagu cgaccagccg ccugaagcca agaaacccaa gaucaaagug guuaacgugg     1860

agcugccuau ugaagcgaau cucgucuggc agcugggcaa ggaucuucug aacauguaua     1920

ucgagacaga agggaaaaug aucaugcagg acaagcucga gaaggagaga aacgaugcca     1980

aaaaugcugu ggaagaguac guuuaugaau uucgcgacaa gcugugcgga cccuacgaga     2040

aauucauuug cgaacaagau caucagaacu uucugcggcu ucucaccgag accgaggacu     2100

ggcuguauga agagggcgaa gaucaggcca agcaggcuua cguggacaaa cuggaggagc     2160

ucaugaagau cgggacaccu gucaagguga gauuccaaga agccgaggaa cgccccaaaa     2220

uguuugagga acugggacag cggcuucagc acuaugccaa gauugcugcg gauuucagaa     2280

auaaagacga gaaguacaac cacaucgacg agagcgaaau gaaaaaggug gagaaguccg     2340

ucaaugaagu uauggagugg augaacaaug ugaugaacgc ccaagcuaaa aagucucugg     2400

aucaggaccc ggugguccgc gcccaggaaa uuaaaaccaa gaucaaagag cucaauaaca     2460

caugugagcc ugugguuacg cagcccaagc ccaagauuga aagcccuaaa cuggagcgga     2520

ccccgaaugg ccccaacauc gauaagaaag aagaggaccu ggaagauaag aauaacuuug     2580

gggccgagcc uccccaucaa aauggcgagu gcuacccuaa cgaaaagaac uccgugaaua     2640

uggaccuuga uugaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  6749
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt5)

<400>  6749
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg ugagacggca gcgccccaga cggcgcgucu      120

gcugggcucu gguugccgug cuccuggcgg aucuucuggc ucucagcgac acccuggccg      180

ugauguccgu cgaucuuggc ucugagagca ugaaaguggc caucguuaag ccuggggugc      240

cgauggaaau cguccugaac aaagagucca gacggaagac acccgugauc guuacgcuca      300

aagaaaauga gcgcuucuuu ggagacucug cugccagcau ggcuauuaag aacccuaagg      360

ccacccugag auacuuccaa caucugcucg gcaaacaggc ggauaauccc cacguggccc      420

uguaucaggc ucgguuuccu gaacacgagc uuacauucga cccccagcgc caaaccgucc      480

auuuucagau cuccucucag cugcaguuca gcccugagga agugcucggg auggugcuga      540

acuacuccag aagccuugcc gaggauuuug cugaacaacc gauuaaggac gccgucauca      600

caguucccgu guucuuuaau caggcggagc ggcgcgccgu gcugcaggcu gccagaaugg      660

cuggacucaa aguccugcag cugaucaacg auaauaccgc cacagcccuc ucuuauggcg      720

uguuccggcg caaggacauu aacaccacgg cucaaaauau cauguuuuac gauauggggu      780

ccggaagcac cguuuguaca auugugaccu aucagauggu caaaacaaag gaggcgggca      840

ugcagccuca acugcagauc agaggcgugg gguucgaccg gacccuugga ggccuggaaa      900

uggagcucag acugcgcgaa cggcuugccg ggcuguuuaa cgagcagaga aagggacagc      960

gcgcuaaaga uguucgggaa aaucccagag ccauggccaa gcuccugcgc gaggcuaacc     1020

ggcugaaaac ggugcucucu gccaaugcgg accacauggc ucaaauugag ggccugaugg     1080

acgaugucga cuucaaggcc aaagugacaa gagucgaguu cgaggaacuu ugcgccgauc     1140

uguuugagcg cgugccuggg cccguucagc aggcucucca guccgccgaa augagccugg     1200

acgagaucga gcaagugauu cuugucggag gcgcuacccg ggugccgaga guucaggaag     1260

ugcugcucaa ggccgucggc aaagaggaac uggggaagaa caucaaugcg gaugaggccg     1320

cugccauggg agcuguguac caggccgcgg cccugucuaa ggcuuucaaa gugaagccuu     1380

uuguuguccg cgacgccgug guguauccca uccucgucga guucacacgg gagguggagg     1440

aagaaccugg cauucauucc cugaaacaca acaagagagu ucuuuuuagc cggauggggc     1500

ccuaccccca gcgcaaagug aucaccuuca acagauacuc ccacgauuuu aauuuccaua     1560

uuaacuaugg agaccugggc uuucucgggc cugaagaucu gcgggucuuc ggaucucaaa     1620

aucugaccac agugaagcuc aagggcguug gcgacagcuu uaaaaaguac ccggauuaug     1680

aguccaaagg gaucaaggcu cacuucaacc ucgacgagag cggagugcug ucucuggaca     1740

gagucgaauc cguguuugag acgcucguug aagauagcgc cgaggaagag ucuacccuga     1800

caaaacuugg caauaccauu agcucccugu ucgggggagg cacaaccccc gacgccaagg     1860

agaacgggac ggauacagug caggaagagg aagagucucc ugcugaaggc agcaaggacg     1920

agcccggaga gcaggucgaa cucaaagagg aagcggaggc cccuguggaa gauggcuccc     1980

agcccccgcc ucccgagccu aagggggacg cuacccccga gggagaaaaa gccaccgaga     2040

aggaaaaugg cgauaaaagc gaggcccaaa agccuucuga gaaggcugaa gccgggcccg     2100

agggaguggc gccggcuccu gaaggcgaga aaaagcagaa acccgcccgc aagcggagaa     2160

uggucgaaga gaucgggguu gagcuggugg ugcuggaccu ucccgaucuc ccugaagaca     2220

aacuggccca guccguccaa aagcugcagg aucucacacu gcgcgaccuu gagaaacagg     2280

aaagagagaa ggcugccaac agccuggaag cguucaucuu ugagacccag gauaagcucu     2340

accaaccgga guaucaggaa gugucuacag aggaacagcg ggaggaaauu uccggcaaac     2400

ugagcgcugc cuccacgugg cuggaggacg agggaguugg cgccaccaca gugaugcuua     2460

aggaaaaacu cgcugagcug cgcaagcugu gucaggggcu uuucuuuaga gucgaagaac     2520

ggaaaaagug gcccgagcgc cugucugccc uugacaaucu gcucaaccau agcuccaugu     2580

uccugaaggg agcuagacug aucccugaaa uggaucaaau uuuuaccgag guggaaauga     2640

caacccuuga gaaaguuauc aaugaaacgu gggccuggaa gaacgcgacc cucgccgagc     2700

aggcuaaacu gcccgccaca gagaagccug ugcugcucuc uaaagacauu gaagcuaaga     2760

ugauggcccu ggaucgggag guccaguacc uucugaauaa ggccaaauuc accaagcccc     2820

gcccuagacc caaagacaag aacggcacac gggcugaacc gccucucaau gcgagcgccu     2880

ccgaucaggg ggagaaagug auucccccug cuggacaaac cgaagacgcc gagcccauca     2940

gcgagccgga aaagguugag acgggcucug aaccugggga uacagagccc cuggaacugg     3000

gcggaccugg cgccgagccc gagcagaagg aacaguccac cgggcaaaaa cgcccccuua     3060

agaacgacga gcugugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6750
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt5)

<400>  6750
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaaa cccagacaca agaccagccc auggaggaag      120

aggaagugga gacguucgcc uuucaggcug agaucgccca gcugaugagc cucauuauca      180

acaccuucua cuccaauaag gaaauuuuuc ugagagagcu uaucucuaac agcuccgaug      240

cgcuggacaa aauucgguau gaaucucuca cagauccgag caagcuggac uccggcaaag      300

agcuucacau caaucugauc cccaacaagc aagaucgcac ccucacaauu gucgacaccg      360

ggaucggaau gacaaaagcu gaucugauua auaaccuggg caccaucgcc aagucuggga      420

cgaaggccuu cauggaggcu cuccaggccg gagcugacau uagcaugauc ggccaguuug      480

ggguuggauu cuacuccgcc uaucuggugg cggaaaaagu gaccgucauu acaaagcaua      540

augaugacga gcaguacgcc ugggaaagcu cugcuggcgg cuccuuuacc gugagaacag      600

auaccgggga gccuauggga cggggcacga aaguuauccu ucaccugaag gaagaccaaa      660

cagaguaucu cgaggaacgc agaaucaaag agauugugaa gaagcauagc caguucaucg      720

gguaccccau uacccuguuu gucgaaaaag agcgggauaa ggaagugucu gacgacgagg      780

ccgaggaaaa agaggauaag gaagaggaaa aagagaagga ggaaaaagag uccgaagaca      840

agccugagau cgaggauguu ggaagcgacg aagaggaaga gaagaaagau ggcgacaaga      900

aaaagaaaaa gaagauuaaa gaaaaguaua ucgaucagga ggagcuuaac aaaacaaagc      960

ccaucuggac ccgcaauccu gacgauauua ccaacgaaga guacggggag uucuacaaau     1020

cucugacaaa ugacugggag gaucaccucg cugugaagca uuuuuccguc gaaggacagc     1080

uggaguucag agcccugcuc uuugugccgc ggcgcgcgcc cuucgaccug uucgagaaca     1140

gaaagaaaaa gaauaacauc aaacuuuaug ugcggcgcgu cuuuauuaug gacaauugcg     1200

aagaacugau cccugaauac cucaacuuca uuagaggcgu uguggauagc gaggaccugc     1260

cccuuaacau cucccgggaa augcugcaac agucuaagau ccucaaagug auucgcaaga     1320

aucuggucaa gaaaugucug gagcucuuua cggagcuggc cgaagauaag gagaacuaua     1380

aaaaguucua cgaacaguuu agcaaaaaua ucaaacuugg cauucacgag gacucccaaa     1440

acagaaagaa gcugagcgag cuccugcggu auuacaccuc ugcuuccggg gaugaaaugg     1500

ugagccuuaa ggacuauugc acaagaauga aagagaauca gaagcacauc uacuacauua     1560

ccggagaaac aaaagaucag guugccaacu cugcuuucgu ggagcgccug cggaagcaug     1620

gccucgaagu caucuauaug auugagccua ucgacgagua cugugugcag caacugaaag     1680

aauuugaggg gaagacccug guuagcguga cgaaggaagg acucgagcug cccgaagaug     1740

aggaggagaa aaagaaacag gaagaaaaga aaacaaaguu cgagaaucuu ugcaagauca     1800

ugaaagacau ucuggaaaag aaagucgaga agguggucgu guccaacaga cucguuaccu     1860

cuccguguug caucgugacc agcacauaug gcuggaccgc caauauggag cgcauuauga     1920

aagcccaggc ucugcgggau aacuccacaa ugggguacau ggcggccaag aagcaccugg     1980

aaaucaaucc ugaccauagc auuaucgaga cgcuuagaca gaaagcugaa gccgauaaga     2040

acgacaaauc ugucaaggac cucgugaucc ugcuguauga gaccgcccuc cuguccagcg     2100

gauuuucucu ugaggauccc caaacacacg cuaaucgcau uuaccggaug aucaaacugg     2160

gccucggcau ugacgaagau gacccuaccg ccgaugacac auccgcggcu guuaccgagg     2220

aaaugccucc ccuggagggg gaugacgaua cgagcagaau ggaagaggug gacugaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  6751
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt5)

<400>  6751
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucca agcuggauuc uggcaaaggg cuccacauca      120

accuggugcc caauaagcag aaccaaaccc uuacaauugu cgacacgaga aucggaauga      180

ccaaaacaga ucugauuaau aaccucggca ccguuacaaa gagcgggacc aaagccuuca      240

uggaggcucu gcaggccgac gcggauaucu ccaugauugg acauuuuggc gugggguucu      300

acucugcuua ucuuguggcc aagaagguca cagugaucag caaacacaau aacgacgaac      360

aguacaccug ggaguccucu gccggaggca gcuuuacggu ucggaccgau gaaugaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  6752
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt5)

<400>  6752
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaag ugcaccaugg cgaggaagag gucgaaaccu      120

ucgccuuuca ggcugagauc gcccaacuga ugagccucau uaucaacaca uucuacucca      180

auaaggagau uuuucugaga gaacuuaucu cuaacgcgag cgacgcucug gauaaaauuc      240

gguaugaguc ccucacggac ccuucuaagc uggauagcgg gaaagaacuu aagaucgaca      300

ucauuccgaa uccccaggag cgcacccuga cacucguuga uaccggaauc ggcaugacaa      360

aagccgaccu gauuaacaau cuggggacca ucgccaaguc cggaacaaag gcuuucaugg      420

aggcccucca ggcuggcgcc gauauuucua ugaucgggca guuuggagug ggcuucuaca      480

gcgcguaucu gguggccgaa aaagucgugg uuauuaccaa gcacaacgac gaugagcaau      540

acgcuuggga auccagcgcc ggcgggucuu uuacggugag agcugaccau ggagagccua      600

ucggccgggg gaccaaaguc auccuucacc ugaaggaaga ucagacagag uaucucgagg      660

aacgcagagu gaaagagguu gugaagaagc auucccaguu cauuggauac cccaucaccc      720

uguaucuuga aaaagagcgg gaaaaggaga uuagcgacga ugaggccgaa gaggaaaaag      780

gcgagaagga agaggaggac aaagacgaug aagagaagcc uaaaaucgaa gacgucgggu      840

cugaugagga ggacgauucc ggaaaggaca agaaaaagaa aacaaagaaa auuaaggaaa      900

aguacaucga ucaggaggaa cugaauaaaa ccaagcccau cuggacgcgc aacccugacg      960

auauuacaca agaggaauac ggcgaguuuu auaaaagccu caccaaugac ugggaggauc     1020

accuggcggu gaagcacuuc ucuguggaag gccagcugga guuuagagcc cuccuguuca     1080

ucccgcggcg cgcucccuuu gaccuuuucg aaaacaaaaa gaagaaaaau aacauuaagc     1140

uguacgucag acggguuuuc aucauggacu ccugcgauga gcucauuccu gaauaucuga     1200

auuuuauccg cgggguggug gacagcgagg aucuuccccu gaacaucucc agagagaugc     1260

uccagcaguc uaaaauucug aaggucaucc ggaaaaauau ugugaagaag ugucuggaac     1320

ucuucagcga gcuggccgaa gacaaagaga acuacaagaa auuuuaugag gcuuucucca     1380

agaaccuuaa acugggaauc caugaggaua gcacaaaucg cagacggcuc ucugagcugc     1440

uuagauacca caccucccaa agcggcgacg aaaugaccuc ucugagcgag uauguuuccc     1500

gcaugaagga aacacagaaa ucuauuuacu acaucacggg ggagagcaag gaacaggugg     1560

ccaacuccgc cuuugucgaa cgggugagaa agcgcggauu cgagguugug uauaugaccg     1620

aaccuauuga ugaguacugc guccaacagc ucaaagaauu ugacggcaag agccuggugu     1680

cugucacaaa agaggggcug gagcuccccg aagaugagga agagaagaaa aagauggaag     1740

aguccaaggc uaaauucgag aaucugugua aacuuaugaa ggaaauccug gacaagaaag     1800

uggagaaggu uaccaucagc aaccggcucg ugucuucccc gugcuguauu gucacaagca     1860

ccuauggaug gacggcgaau auggaaagaa ucaugaaggc ccaggcucug cgcgauaacu     1920

ccacaauggg cuacaugaug gccaaaaagc aucuggagau uaauccugac caccccaucg     1980

uggaaacccu ucggcagaaa gccgaggcug auaagaacga caaagccguu aaggaccucg     2040

ugguccugcu guuugagacc gcgcuccugu cuagcggcuu cucccuugaa gauccucaaa     2100

cacacucuaa uagaauuuau cgcaugauca agcuggggcu cggaaucgac gaggaugaag     2160

uggcugccga ggagcccaac gccgcugugc ccgacgaaau uccuccgcug gagggcgaug     2220

aagacgccag ccggauggag gaaguugauu gaggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  6753
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt5)

<400>  6753
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agagcccugu gggugcucgg ccugugcugu guccuucuga      120

ccuucgggag cguucgggcu gacgaugagg uggacgugga uggaacaguc gaagaggacc      180

ucggcaaguc ccgcgaaggg ucuagaacgg augacgaggu gguucagcgg gaagaggagg      240

ccauccaacu ggauggacuu aacgcgagcc agauucgcga acugagagag aaauccgaaa      300

aguuugcuuu ccaggccgag gugaaucgga ugaugaaacu caucauuaac ucucuguaca      360

agaauaaaga gaucuuucug cgcgaacuca uuagcaacgc cuccgacgcu cuggauaaga      420

ucagacuuau cucucugacc gacgagaaug cccucagcgg caacgaagaa cugacaguca      480

agauuaaaug cgauaaggag aaaaaucuuc ugcacgugac cgacacaggg guuggaauga      540

cccgggagga gcucgugaag aaccugggca caaucgcuaa auccggcacc agcgaguucc      600

ugaauaagau gacggaggcc caggaagaug ggcaaucuac cuccgagcuc auuggacagu      660

uuggcgucgg guucuauagc gcguuucugg uggccgacaa ggugaucguc acaucuaaac      720

auaacaauga cacccagcac auuugggaau ccgauagcaa cgaguucucu guuaucgcug      780

acccccgcgg aaauacacuu ggcagaggga ccacgauuac acuggugcuc aaggaggaag      840

ccuccgauua ccuggagcuu gacaccauca aaaaccuggu gaagaaauau agccaguuua      900

ucaauuuccc uauuuacguc ugguccucua agacagaaac cguggaggaa ccgauggagg      960

aggaagaggc ugccaaagaa gagaaggagg aaagcgauga cgaggcggcc guugaagagg     1020

aagaggagga aaagaaaccc aagaccaaaa agguggagaa aacagucugg gauugggaac     1080

ucaugaacga caucaagccu auuuggcaac ggcccuccaa ggagguggaa gaggaugagu     1140

auaaagccuu uuacaagagc uucucuaaag aauccgacga uccuauggcu uauauccauu     1200

uuacggcuga gggagaaguu accuucaaga gcauucuguu cgugcccaca ucugccccuc     1260

gcggccuguu ugacgaguac ggcagcaaaa aguccgacua caucaagcuc uaugucagac     1320

ggguguucau caccgaugac uuucacgaua ugaugccgaa auaccugaac uucgucaagg     1380

gggugguuga cucugaugac cuuccccuga augugagccg cgaaacacuc cagcagcaua     1440

aacugcuuaa ggucauucgg aaaaagcugg ugagaaagac ccucgauaug aucaaaaaga     1500

uugccgacga uaaauauaac gacacguuuu ggaaggaguu cggaacaaau aucaaacugg     1560

gcguuauuga ggaucacucc aacagaaccc gccuggcuaa gcuccugcgg uuucagagcu     1620

cucaccaucc uaccgacauc acaucccuug aucaauacgu ggaaagaaug aaagagaagc     1680

aggacaagau cuauuucaug gcggggagcu cucgcaaaga agccgagucc agccccuuug     1740

ucgagcggcu gcucaagaaa ggauacgaag ugauuuaucu gaccgagccu guggacgaau     1800

acuguaucca ggcucugccc gaguucgaug gcaagagauu ucaaaauguu gccaaagaag     1860

gggucaaguu cgacgagucc gagaagacaa aagaaucucg cgaggccgug gaaaaggagu     1920

uugaaccgcu ucucaacugg augaaagaua aggcucugaa agacaagauu gagaaggccg     1980

uggucagcca gcggcugacg gaguccccuu gcgcgcucgu ggcuucucag uacggaugga     2040

gcggcaauau ggaaagaauc augaaagccc aggccuauca aaccggcaag gauauuucca     2100

caaacuacua ugcuagccag aaaaagaccu ucgagaucaa uccccgccac ccucugauuc     2160

gggacaugcu uagacgcauc aaagaagaug aggacgauaa gacaguucug gaccucgccg     2220

ugguccuguu cgaaaccgcu acgcugcggu cuggguaccu ucuccccgau accaaggccu     2280

auggagacag aaucgagcgg augcugcgcc ugucccucaa cauugauccc gacgcgaaag     2340

uggaggaaga accugaagag gagccggaag agacagccga agacaccaca gaggauaccg     2400

aacaggacga ggaugaggaa auggacguug gcacggauga ggaagaggaa acagcuaagg     2460

agagcaccgc cgagaaagac gaacugugag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  6754
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt5)

<400>  6754
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagagagc ugcgggcucu ccugcuuugg ggccgcagac      120

ugcggccccu ccugcgcgcc ccugcgcuug cugccgugcc cgggggaaag ccgauccugu      180

gcccuagacg gaccacagcc cagcucggcc cccgcagaaa cccugcuugg agccugcaag      240

ccgggcggcu guucuccacg cagaccgcug aagacaaaga ggaaccccuc cacucuauua      300

ucagcuccac agagucuguc cagggaagca ccuccaagca ugaauuucag gccgagacaa      360

agaagcugcu ugauauuguu gcgcgcucuc uguacagcga gaaagaagug uucaucagag      420

agcucauuuc caaugccagc gacgcucugg aaaaacuucg gcacaagcug gugucugaug      480

gccaagcccu cccugagaug gagauccauc ugcagaccaa cgcugaaaaa gggacaauca      540

ccauucagga cacgggaauc ggcaugaccc aggaggaacu ggucuccaau cucggcacaa      600

uugcccgcag cgggucuaag gcguuucugg augcccuuca aaaccaggcu gaggccucca      660

gcaaaaucau uggacaguuc ggcguggggu uuuauucugc uuucaugguu gccgacagag      720

uggaagucua cucccggagc gccgcuccgg gaucccuggg cuaucagugg cucucugaug      780

ggagcggagu guuugagauc gcggaggccu ccggcguucg caccggcaca aagauuauca      840

uccaccugaa aagcgacugu aaggaguucu cuuccgaggc uagagugcgg gaugucguga      900

ccaaguacag caauuuugug ucuuuccccc uuuaucugaa cgggagacgc augaauacgc      960

uccaagccau uuggaugaug gacccuaaag auguccggga auggcagcau gaggaauuuu     1020

acagauaugu ugcccaggcu cacgacaagc cccgcuacac acugcacuac aaaaccgaug     1080

ccccucugaa cauccggagc auuuucuaug ugcccgacau gaagccgucc auguuugacg     1140

ugucuagaga gcucggaagc uccgucgcgc uguacagccg caaagugcuu auccaaacaa     1200

aggcuaccga uauucugccu aaauggcucc gguucaucag aggcguugug gacucugagg     1260

auaucccccu gaaucuuucc cgcgaacugc uccaggagag cgcccugauu cggaagcuga     1320

gagacguccu ccagcagcgc cugaucaagu ucuuuauuga ucaaucuaaa aaggacgccg     1380

aaaaauaugc uaaguucuuu gaggauuacg ggcuuuucau gcgggaagga aucgugaccg     1440

ccacagagca ggagguuaaa gaagacauug cuaagcugcu cagauaugag uccagcgccc     1500

ugccuuccgg ccagcugacg ucucuuagcg aauacgcguc ccggaugcgc gccgggacca     1560

gaaacaucua uuaccucugc gcucccaauc ggcaucuggc cgagcacucu cccuacuaug     1620

aggcuaugaa gaaaaaggau acagaagugc uguuuuguuu cgagcaguuu gacgaacuca     1680

cccugcuuca ucugagagag uucgauaaaa agaaacucau cagcgucgaa acagacauug     1740

uggucgacca cuacaaggag gagaaguuug aagaucgcuc cccugccgcg gagugccuga     1800

gcgaaaaaga gaccgaagaa cugauggccu ggaugcggaa cgugcuugga ucuagaguua     1860

cgaaugugaa ggucacacuc cgccuggaca cccacccggc uauggugacc guucuggaga     1920

ugggcgccgc uagacauuuc cuccggaugc aacagcuggc caaaacacag gaggaacgcg     1980

cccagcuucu gcaacccacc cucgaaauca acccuagaca cgcucugauu aagaaacuga     2040

aucagcuucg ggcguccgag cccggccucg cccagcugcu gguggaucag aucuaugaaa     2100

acgcuaugau ugccgccggg cucgucgacg auccucgcgc uaugguggga agacugaacg     2160

agcuucuggu gaaggcccuc gagcggcauu gaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  6755
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt5)

<400>  6755
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagauca gcucccugcc cacccagcuu uucaaaugcu      120

guuuuugcga cuuccugaag gugaaaaugc acacaauguc uagcucccau cucuuuuacc      180

uggcccucug ucugcuuacg uucaccucua gcgcuacagc cgggccugag acccugugcg      240

gagcggaacu cgucgaugcu cugcaauuug uuuguggcga cagaggguuc uauuuuaaca      300

agccgacagg auacggcucc ucuagccggc gcgcucccca gaccgggauu guggaugagu      360

gcuguuucag auccugcgac cugcggcgcc ucgaaaugua uugugccccu cugaaacccg      420

ccaagagcgc cagaucugug cgggcucagc gccacacaga uaugccuaag acccagaaag      480

agguccaucu uaagaaugcc uccagaggaa gcgcgggcaa caaaaauuac cggaugugag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  6756
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt5)

<400>  6756
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca ugggaaagag caugcuggug cuccugaccu      120

uccuugccuu ugcuuccugc uguauugccg cguacagacc uucugagaca cugugcgggg      180

gcgaacucgu cgacacgcug caguucguuu guggggaucg gggauuuuau uucagccgcc      240

cggcuuccag agugucucgg cgcagcagag gcaucgugga ggaaugcugu uuucgguccu      300

gcgaccuugc ccugcucgag accuacugug ccacacccgc uaaaucugaa cgcgauguca      360

gcaccccucc cacagugcug ccugacaacu uccccagaua uccuguuggg aaguuuuucc      420

aauacgauac cuggaaacag uccacacagc ggcugcgcag aggacucccg gcccugcuuc      480

gggcucgcag aggccacgug cuggccaagg agcucgaggc guuucgggaa gccaaacgcc      540

auagaccccu gauugcccuu ccuacccagg accccgcuca cggcggggcu ccucccgaga      600

uggccagcaa ucggaaguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  6757
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt5)

<400>  6757
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagcuucu ccaccucugc cuuuggcccc guggcuuuca      120

gccuggggcu ccugcuuguc cugccugccg cguuuccggc ucccguuccu cccggagagg      180

acuccaagga uguggccgcc ccucacagac agccccucac aucuagcgaa cggaucgaca      240

aacaaauucg cuacauccug gauggcauuu ccgcucuuag aaaggagacg ugcaauaaau      300

cuaacaugug ugaaagcucc aaggaggccc uggcugaaaa uaaccucaau cugccuaaaa      360

uggccgagaa ggacgggugc uuccagagcg gauuuaacga ggaaaccugu cuggugaaga      420

ucauuacagg ccuccuggag uucgaagucu aucuugagua ccugcagaau cgguuugagu      480

cuuccgaaga acaggcgcgc gccgugcaaa ugagcaccaa aguucucauc caguuccugc      540

agaagaaagc uaagaaccuu gaugccauca caaccccgga ccccacaacc aaugcuucuc      600

ugcucacgaa acugcaggcc caaaaccagu ggcugcagga uaugaccaca caucucauuc      660

ugagauccuu uaaggaguuc cuucagagcu cucugcgggc gcuccgccaa augugaggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  6758
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt5)

<400>  6758
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcucu ggcugagagg cuuccuucug gccagcugcu      120

ggaucauugu gcgguccucu ccuaccccgg ggagcgaggg acacuccgcu gcccccgacu      180

guccuucuug cgcgcucgcu gcccugccca aggauguccc uaacagccag cccgaaaugg      240

uugaggccgu gaaaaagcau auccuuaaua ugcugcaccu caaaaagcgc ccugacguga      300

cacaaccggu ccccaaagcu gcccugcuga acgcuauuag aaagcuccau gugggcaagg      360

uuggggaaaa uggauacgug gagaucgaag augacauugg ccggcgcgcc gagaugaacg      420

agcugaugga acagacgucc gagaucauca ccuuugcgga aucugggaca gccagaaaaa      480

cccuucacuu cgagauuagc aaggagggau ccgaucugag cgucguggaa cgggcugagg      540

uuuggcucuu ucugaaagug ccuaaggcca aucgcacaag aaccaaaguc acaauccggc      600

uuuuccagca gcaaaagcau ccccagggcu cucuggacac cggcgaagag gcugaagagg      660

uggggcucaa gggagagcgc uccgaacugc ugcucagcga gaaagugguc gaugccagaa      720

agucuacgug gcacguuuuu ccugugucca gcucuauuca gcggcugcuu gaccagggca      780

aauccagccu ggaugugcgc aucgcgugug aacaaugcca ggaguccggg gccucucucg      840

uccugcuugg aaagaaaaag aaaaaggaag aggagggcga agggaagaaa aagggaggcg      900

gcgaaggggg agcuggcgcc gacgaggaga aagaacagag ccacagaccc uuccugaugc      960

uccaggcucg gcaauccgag gaucauccgc accgcagacg gagacgcggg cuggagugug     1020

acggaaaggu gaacauuugc uguaaaaagc aguuuuucgu uagcuuuaag gauaucggcu     1080

ggaaugacug gauuaucgcc ccuucugggu aucaugccaa cuacugcgaa ggagaguguc     1140

ccucccacau cgcuggcacc agcggcucua gccuguccuu ccacucuaca gugauuaauc     1200

auuaucggau gagagggcac agcccuuuug cgaaccucaa auccugcugu guccccacca     1260

agcugcgccc caugagcaug cuuuacuaug acgauggaca gaauaucauu aaaaaggaca     1320

uccaaaacau gauuguggaa gagugcggcu gcucuugagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  6759
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt5)

<400>  6759
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccugc ccgggagagc ccucggagcu gccugccugc      120

uucugcucgc ggcuggcugg cuggggccug aggccugggg aagcccgaca cccccuccca      180

ccccugccgc ucccccuccg cccccucccc cuggcucccc cgggggaucu caggauacgu      240

guaccagcug cggcggcuuc cggcgcccgg aggaacuugg gagaguggac ggagauuuuc      300

uggaagccgu caagcggcac auccucuccc gccugcaaau gagaggccgg ccuaacauua      360

cacaugcugu ucccaaagcc gcgaugguga ccgcccugcg caagcuccac gcugggaaag      420

ugagagagga cggacggguc gaaaucccuc aucuggaugg ccacgccucu cccggggcug      480

acggacagga gcgcgugagc gagauuaucu ccuucgccga aacagauggc cuugcgucua      540

gcagaguucg gcuguacuuu uucauuucca augagggcaa ccagaaucuc uuuguggucc      600

aggccagccu guggcuuuau cugaagcucc ugcccuacgu gcuggaaaaa gggucucgca      660

gaaagguucg ggugaagguc uauuuccaag agcagggaca uggcgaccgc uggaacaugg      720

uggagaaaag aguggaucuc aagcgguccg gguggcacac cuuuccucug acagaagcua      780

uccaggcccu uuucgagaga ggagaacgcc ggcugaaucu cgacguccag ugugauagcu      840

gccaagagcu ggcuguugug ccgguguuug ucgaccccgg cgaagagucu cacagaccuu      900

ucgugguugu gcaggcccgc cuuggggauu cccggcauag aauccgcaaa cggggacugg      960

agugugacgg cagaaccaac cucugcuguc gccagcaguu uuucauugac uuucggcuga     1020

ucggcuggaa ugauuggauu aucgccccca cgggguacua uggaaacuac ugcgaaggca     1080

gcuguccugc uuaucuggcg gggguccccg gaucugccuc cagcuuccac accgcugugg     1140

uuaaucaaua cagaaugcgc ggccucaacc cggggacagu caauuccugc uguauuccua     1200

ccaagcuguc uacaaugagc augcuuuacu ucgacgauga guauaacauc gugaaacggg     1260

acgugcccaa uaugauuguc gaagagugcg gcugcgccug aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  6760
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt5)

<400>  6760
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugagag ugcuccugcu uaccgcucug acacucugcc      120

acggcuucaa ccuggacacg gagaaugcca ugaccuuuca ggaaaacgcg cggggguucg      180

gacaaagcgu gguucagcuu cagggcuccc gcgugguggu cggggcuccc caggagaucg      240

uggccgccaa ucaaagagga ucucuguacc agugugauua uagcacaggc uccugcgaac      300

cuauucggcu ccagguuccg guggaggcug ucaacauguc ucuggggcug agccucgccg      360

cuaccacauc cccuccucag cugcuugccu guggacccac cgugcaucaa acaugcucug      420

aaaauaccua cguuaagggc cuguguuuuc ucuucggcag caaccugcgc cagcagccuc      480

agaaauuucc cgaggcgcuu agagggugcc cucaagagga cuccgauauc gccuuccuga      540

uugacggaag cggcucuauc auuccgcacg auuuucggcg caugaaggag uucgugucca      600

cggucaugga acagcucaaa aagagcaaaa cccuguuuuc ucugaugcag uauuccgaag      660

aguucagaau ccauuuuaca uucaaggagu uucaaaauaa ccccaauccu cggagccucg      720

ugaagcccau cacccagcug cuugggcgca cacacaccgc uacgggaauu agaaaagugg      780

uccgggaacu guucaacauc acaaauggcg cccgcaagaa cgcuuucaaa auucucguug      840

ugaucaccga cggggagaag uuuggagauc cucugggcua cgaagacgug auucccgagg      900

ccgauagaga aggcgucauc cgguauguga uugggguugg agacgcguuc cgcucugaga      960

aauccagaca ggagcuuaau acaaucgcca gcaagccgcc ucgggaucau guguuucagg     1020

ucaacaauuu cgaagcucug aagaccaucc aaaaccagcu cagagagaaa auuuuugcca     1080

ucgaaggcac ccagacaggg uccucuagcu ccuucgagca cgaaaugagc caggagggau     1140

uuucugcugc cauuacgucc aacggccccc ugcugagcac cguggggucu uacgacuggg     1200

ccggaggcgu uuuccucuau acaagcaagg agaaauccac cuuuaucaau augacacgcg     1260

uggauucuga caugaacgac gcuuaccugg gcuacgcggc cgcuauuauc cuucggaaua     1320

gaguccaaag ccuggugcuc ggggccccuc gcuaucagca caucggacug gucgccaugu     1380

uccggcagaa caccggcaug ugggaaucca augcuaacgu gaaggggacg cagauuggag     1440

ccuacuuugg cgcgagccuu uguucuguug auguggacuc caaugggagc acagaucugg     1500

uccucaucgg cgcuccccau uauuacgagc aaaccagagg aggccaggug ucuguuugcc     1560

cccugccucg cgggcgggcc agauggcagu gugacgccgu gcuguaugga gaacagggcc     1620

aaccgugggg gcgcuucgga gcugcccuca ccguccuggg cgaugugaac ggggacaaac     1680

uuacagaugu ggcuauuggc gcccccggag aggaagacaa ucggggcgcg guuuaccugu     1740

uucacgggac cuccggaagc ggcaucuccc cuucucauag ccagagaauu gccgggucca     1800

agcucucucc ccgccugcag uauuucggac aaagccuguc cggcgggcag gaucuuacaa     1860

uggacggccu cgucgaucug acggugggag cucagggcca cgugcugcuc cugcggagcc     1920

agccuguccu uagagugaaa gccaucaugg aguucaaccc ccgggagguu gcucgcaaug     1980

uguuugaaug caacgaccaa gucgugaagg ggaaggaggc cggagaaguu agaguguguc     2040

ugcacgucca gaaaucuacc cgggacagac uccgcgaggg ccagauccag uccgugguua     2100

cauacgaucu ggcgcuggac agcgggcggc cgcauucuag agccguguuc aaugagacca     2160

agaacuccac acgcagacaa acccaggucc uuggacucac gcagaccugc gaaacacuga     2220

aacugcagcu cccuaauugc auugaggauc ccgugagccc uaucgugcug cggcuuaacu     2280

uuucucuggu cggcacaccc cucagcgcuu ucgggaaccu gcgcccuguu cuggccgaag     2340

acgcucaaag acuuuuuacc gcccucuucc ccuuugagaa gaauuguggc aacgauaaua     2400

uuugccagga cgaucugucc aucaccuuca gcuuuauguc ucuggacugu cucguggugg     2460

gaggcccgcg ggaguucaac gucacgguga caguucgcaa ugauggggaa gacuccuaca     2520

gaacccaggu gacauuuuuc uuuccucugg aucuuagcua ucggaaaguc uccacccugc     2580

aaaaccagcg cucucagaga agcuggcggc ucgccugcga guccgcuucu agcaccgaag     2640

uguccggagc gcugaagucu acaagcuguu ccauuaauca ccccaucuuc cccgagaaca     2700

gcgaaguuac guucaauauu accuuugacg uggauucuaa ggccucccug ggcaacaaac     2760

uucuccugaa ggcuaauguc acaagcgaga acaauaugcc ucgcaccaac aaaacagagu     2820

uccagcugga acucccggug aaguacgccg uuuauauggu ggucaccucu cauggggugu     2880

ccacgaaaua ccugaauuuu acagccagcg agaacaccuc uagagugaug caacaccagu     2940

aucaggucuc caaccuugga cagcggagcc ugcccaucuc ccucguuuuc cuggugccug     3000

ugagacugaa ucaaaccguc aucugggacc gcccccaggu gacauuuagc gaaaaccuuu     3060

cuagcacaug ccauaccaag gagcggcugc cuucccacuc ugacuuccuc gcugaacuga     3120

gaaaggcccc cguugugaau uguagcauug cggucugcca gcgcauccag ugugauauuc     3180

ccuuuuucgg cauccaagag gaauuuaacg cuacgcucaa aggcaaucug uccuucgacu     3240

gguacauuaa gaccucucac aaccaucuuc ugaucgugag cacagccgag auccucuuua     3300

augauuccgu uuucacccug cugcccgggc agggagccuu cgugcggucu cagacagaga     3360

ccaaagucga accguuugag gugccuaacc cccuuccucu gauugucggc agcuccgucg     3420

ggggacuccu gcuccuggcu cuuaucacgg ccgcgcugua uaagcucggc uucuuuaaaa     3480

gacaguacaa ggacaugaug agcgaagggg gacccccggg cgcugagccu caaugaggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  6761
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt5)

<400>  6761
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucagccuga agacccuccc cuuucugcuu cugcuccacg      120

ugcagaucuc caaagccuuc ccugucucua gcaaggagaa aaacacaaag acgguucaag      180

acuaccugga aaaauuuuau cagcuuccgu ccaaucagua ccagucuacc agaaagaacg      240

gcacaaaugu gauuguggag aagcugaaag aaaugcaacg guucuuuggg cucaacguca      300

ccggaaagcc caaugaggaa acacuggaua ugaugaaaaa gccucgcugc ggcgugcccg      360

acagcggggg auucaugcug accccuggca accccaaaug ggagagaaca aaucucaccu      420

aucggauccg caacuacacg ccucagcugu ccgaggcuga aguugagaga gccauuaagg      480

augcguuuga acuuuggucu guggcuagcc cgcugaucuu cacccggauu ucccaggggg      540

aggccgacau caauaucgcc uuuuaucagc gcgaucaugg agacaacagc cccuucgaug      600

gcccuaaugg cauucucgcu cacgccuuuc aacccgggca gggaaucggc ggggacgcuc      660

auuucgaugc cgaggaaaca uggaccaaca caucugcgaa uuacaaccug uuucuugucg      720

ccgcucacga guucggacau ucccugggcc ucgcccacag cucugacccu ggggcucuga      780

uguaucccaa uuacgccuuc agagaaaccu ccaacuacag ccugccgcag gaugacauug      840

auggaaucca ggcgauuuau ggccucucuu ccaacccuau ccaacccacg ggcccuagca      900

cacccaagcc cugugacccu ucccugaccu uugacgccau uacaacccuu cggggagaga      960

uccuguucuu uaaagaucgc uacuucugga gacggcaccc gcagcuccag cgcguggaaa     1020

ugaauuuuau cucucuguuc uggcccagcc uuccuaccgg gauucaagcu gccuaugagg     1080

acuuugauag agaccugauc uuccucuuua agggcaacca guacugggcu cuguccgggu     1140

augauauucu gcagggauac cccaaagaca ucagcaauua uggcuucccu ucuuccguuc     1200

aggccauuga ugccgcugug uuuuaccgga gcaagacaua cuucuuuguc aacgaccaau     1260

ucuggcgcua ugauaaucag agacaguuca uggagcccgg guacccgaaa ucuaucagcg     1320

gagcguuucc uggcaucgaa uccaaggugg acgccguguu ccagcaagag cacuuuuucc     1380

augucuuuuc uggcccccgg uauuacgcuu ucgaucucau ugcccagaga guuacgcgcg     1440

uggcccgggg gaacaaaugg cugaauugca gauauggaug aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  6762
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt5)

<400>  6762
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguggc agccccucgu gcugguccuu cugguucucg      120

gcugcuguuu cgccgcuccu agacaacggc aguccacccu ggugcuuuuu ccgggggacc      180

ugcgcacaaa ccucacggau agacagcugg ccgaggaaua ccuguaucgg uacggauaua      240

cccgcguggc ggagaugaga ggcgaaucua aaagccucgg gcccgcucug cuucugcucc      300

agaaacaacu gucccuuccu gagacaggag aacuggacuc ugccacccuc aaggccaugc      360

ggacaccccg cugcggcguc ccugaucugg ggagauucca gaccuuugag ggagaccuga      420

aauggcacca ucacaauauc acauacugga uucagaacua uagcgaggau cucccccggg      480

cugugaucga cgaugccuuc gcucgcgccu uugcgcugug guccgccguu accccucuua      540

cguucaccag aguguacucu cgggacgcug auauugucau ccaguuuggc guggccgaac      600

auggcgacgg guauccguuc gauggaaagg acggccugcu cgcucacgcc uuucccccug      660

ggcccgggau ucaaggcgau gcgcauuucg acgacgauga gcuguggagc cuugggaaag      720

gaguuguggu cccuacacgc uuuggcaaug ccgacggcgc ugccugucac uuccccuuua      780

ucuucgaagg gagauccuac agcgcuugca ccacagaugg acggucugac ggccugccgu      840

gguguuccac cacggccaac uacgauacag acgaucgcuu cggguuuugc ccuagcgaga      900

gacucuauac ccaggacgga aaugccgaug gcaagcccug ucaguucccu uuuaucuucc      960

aggggcaauc uuacuccgcu ugcacaaccg acggacggag cgauggcuau agauggugug     1020

cgaccacagc caacuacgac cgcgacaagc uguuuggcuu cugccccacg cgggcugauu     1080

cuaccgugau gggaggaaau uccgccggcg agcugugugu guuucccuuc acauuucucg     1140

ggaaagaaua uagcacaugc accuccgagg gaagaggcga cgggcgccug uggugcgcca     1200

ccacgucuaa cuucgauagc gacaagaaau ggggcuuuug uccugaucag ggauacuccc     1260

uuuuccuggu cgcugcccac gaauuuggcc augcgcucgg gcuggaccac agcucuguuc     1320

cggaggcucu uauguauccc auguaccggu ucacagaagg accuccccug cauaaggaug     1380

acgugaaugg cauuagacac cucuacgggc cucgccccga gccggagccu cggcccccua     1440

ccaccacaac accccagccu accgcgcccc cgacggugug cccuaccgga ccucccacag     1500

uccaccccuc cgaaagaccg accgccggcc ccacagggcc ucccagcgcu ggcccuaccg     1560

gacccccuac ggccggcccc ucuaccgcua caaccgugcc gcugagcccu guugaugacg     1620

ccuguaacgu gaauaucuuc gaugcgauug ccgagaucgg gaaccaacug uaucucuuua     1680

aagacggaaa guacuggcgc uucuccgaag gccggggguc uagaccccag ggaccuuuuc     1740

ugauugcuga uaaguggccc gcccuuccgc gcaaacugga cagcgucuuc gaggaacggc     1800

ucuccaagaa acuguuuuuc uuuagcggca gacaggugug gguuuauaca ggggcuucug     1860

ugcugggccc ucggcgccuu gacaagcucg gacugggcgc cgaugucgcc caggugaccg     1920

gggcccugag auccggacgg ggcaaaaugc uccuguucag cgggagacgc cuuuggcggu     1980

uugacgucaa ggcucaaaug guggauccca gaucugccuc cgagguugac cgcauguucc     2040

cuggagugcc ccuggauacg caugacgucu uucaguacag agagaaggcu uauuucugcc     2100

aggaucgguu uuacuggcgc gugagcucca gaucugaacu caaucagguu gaccaagugg     2160

gcuaugucac auacgauauc cugcaguguc ccgaggacug aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  6763
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt5)

<400>  6763
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg ugcuggccgc uuuccucuuu cugagcugga      120

cccauugcag agcccuuccu cugccguccg ggggagacga ggaugaccuc ucugaagagg      180

aucugcaguu cgcggaacgg uaccuucgca gcuauuacca ccccacaaac cuggcuggca      240

uccucaagga gaaugccgcc uccucuauga cggaaagacu gcgggagaug cagagcuuuu      300

ucgggcugga ggucaccgga aaacucgacg auaacacacu ggacguuaug aagaaaccuc      360

gcuguggcgu gcccgaugug ggggaauaua augucuuucc uagaacccuu aaguggucca      420

aaaugaaccu gacauaccgg auugugaauu auacccccga caugacacau ucugagguug      480

aaaaggcuuu caagaaagcc uuuaaggugu ggagcgaugu caccccucuc aacuucacgc      540

gccugcacga cggaaucgcu gauauuauga ucuccuuugg cauuaaagag cauggcgacu      600

ucuacccguu ugaugggccc agcggacuuc uggcccacgc guucccuccc ggcccuaauu      660

augggggaga cgcccacuuu gacgaugacg agaccuggac aucuuccagc aagggcuaca      720

accucuuccu gguggcugcc caugaguucg ggcacucucu gggacucgau cauuccaaag      780

accccggcgc ucugauguuu ccgaucuaca ccuauacagg caagagccac uucaugcuuc      840

cugaugacga uguucaaggg auccagucuc uguacggacc cggcgacgag gauccuaauc      900

ccaagcaccc caaaaccccu gacaagugcg auccgucccu cagccuggac gccauuacgu      960

cccuuagagg ggaaacaaug aucuuuaaag accgguucuu uuggcgccug cauccccagc     1020

aaguggaugc ggaacucuuc cugaccaagu cuuuuuggcc ugaacugccc aacagaauug     1080

acgccgcuua ugagcacccu agccaugauc ucaucuucau uuuucgggga cgcaaauucu     1140

gggcccugaa uggcuacgac auccuugagg gguaucccaa gaaaauuucc gaacugggac     1200

ucccgaagga ggucaagaaa aucagcgcug ccgugcacuu ugaagauaca ggcaagaccc     1260

ugcuuuucuc uggcaaccag guguggagau acgacgauac caaucauauc auggacaaag     1320

auuauccucg gcugauugag gaagacuuuc ccgggaucgg agauaagguc gacgccguuu     1380

acgagaaaaa cggcuacauu uauuucuuca augggccuau ccaguuugag uacuccauuu     1440

ggagcaaccg caucgugaga gugaugcccg cuaacucuau ccucuggugu ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6764
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt5)

<400>  6764
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acacaacgga agacuacgau accacaaccg      120

aguucgacua uggcgaugcc acaccuugcc agaaggugaa ugaaagagcu uuuggggccc      180

aacugcuccc gccccuguac agccuugucu ucguuaucgg acuggugggc aacauucucg      240

ugguccuggu gcuuguucag uauaaacggc ugaagaauau gaccuccauc uaccuccuga      300

accuggcgau uucugaccuc cuguuucuuu ucacacugcc uuuuuggauc gauuauaaac      360

ucaaggacga uuggguguuc ggggacgcua uguguaaaau ucugagcgga uuuuacuaua      420

ccggccuuua cuccgagauc uucuuuauca uucugcucac gaucgaucgc uaccuggcca      480

uuguccacgc cguguucgcu cugagagccc ggaccguuac auuuggggug aucaccucua      540

uuaucauuug ggcucucgcc auccuggcga gcaugcccgg acuuuauuuc uccaagacac      600

agugggaauu uacccaucac acgugcucuc ugcauuuccc ucacgagagc cuccgcgagu      660

ggaagcuguu ccaggcccuu aaacugaauc ucuuuggccu gguccugccc cuccugguga      720

ugaucauuug uuacacaggc aucauuaaga uccuucugag acggccuaac gagaaaaagu      780

ccaaagcugu gcgccucauu uucgucauca ugaucaucuu uuuccuguuu uggaccccgu      840

auaaucuuac aauucugauu agcguuuucc aagacuuucu cuucacccau gaaugcgaac      900

agucuagaca ccuggaucug gccguccagg ugaccgaggu gaucgcuuac acacacuguu      960

gcgugaaccc cguuauuuau gccuuugugg gggagcgguu ccgcaaguac cucagacagc     1020

uguuucaucg gcgcgucgcg gugcaccuug uuaaguggcu gccuuuccuc uccguggaca     1080

gacuggaacg ggucagcucu acguccccca gcaccggaga gcaugaacug ucugccggcu     1140

uuugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  6765
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt5)

<400>  6765
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agaacccugg ccugccuccu gcuucugggc uguggguacc      120

ucgcucacgu gcuggccgag gaagcggaga ucccccggga agucauugag cgccuugcua      180

gaagccagau ccauuccauu cgggaccugc aacgccuccu ggaaaucgau ucuguuggaa      240

gcgaggacuc ccuggauaca ucucucagag cccacggcgu gcaugccacg aagcacgugc      300

cugagaaacg gccgcugccc auucgcagaa agcggagcau cgaagaggcu gucccugccg      360

ugugcaaaac ccgcacaguu aucuaugaaa uucccagauc ccagguggac ccuaccucug      420

cuaacuuccu uaucuggccc ccuugugucg aggugaagcg gugcacaggg uguugcaaua      480

ccagcuccgu uaaaugucag ccgagccgcg ugcaucacag aucugucaag guggccaagg      540

uggaguacgu ccggaaaaag cccaaacuga aggaaguuca ggugcgccuc gaggaacacc      600

uggagugcgc gugugccaca accucccuua acccugauua uagagaagag gacacgggac      660

ggcccagaga gagcggcaaa aagcgcaagc ggaaaagacu gaagccuacc ugaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  6766
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt5)

<400>  6766
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagaugcu gggcccuguu ccucagccug uguugcuacc      120

uucggcuggu guccgcugag ggcgacccca ucccugagga acucuaugaa augcugucug      180

aucacagcau ucgcuccuuu gacgaucuuc agagacugcu ccauggggac ccgggagagg      240

aagauggcgc cgagcuggac cugaauauga cccggucuca cagcggggga gagcucgaau      300

cccuggcgcg cggcagacgg ucucuuggga gccugacaau cgcugagccc gccaugauug      360

ccgaauguaa gacgcgcacc gaggucuucg agaucuccag acggcucauu gaucgcacaa      420

acgcuaauuu ucugguuugg ccucccugcg uggaagugca aagauguagc ggaugcugua      480

acaaucggaa cguccagugc cgcccuaccc aggugcagcu uagacccguu caagugcgga      540

aaaucgagau cguccgcaag aaaccuauuu ucaagaaagc cacagugacc cuggaagacc      600

aucucgcuug uaagugcgag acaguugccg cggccagacc ggugacccgg ucucccggcg      660

gcucccagga acagagagcu aagacgccuc agacccgcgu cacaauccgg accgugagag      720

ugcgccggcc cccuaaaggg aagcacagaa aauuuaagca uacacacgau aaaaccgccc      780

ugaaggagac gcugggagcu ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  6767
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt5)

<400>  6767
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguucg gccuccugcu ucugaccucc gcccucgcug      120

ggcagagaca aggaacacag gccgagucua accugagcuc caaguuucag uucucuagca      180

auaaagaaca gaacggcgug caagaccccc agcacgagcg gaucauuacg gucuccacca      240

augggucuau ccauagcccu cgcuuuccgc acacauaccc cagaaacacc guucuugugu      300

ggcggcuggu ggcggucgaa gagaaugugu ggauucagcu cacauucgau gaacgcuuug      360

gacuggagga cccugaggau gacaucugca aguaugauuu cguugaagug gaggaacccu      420

ccgacggcac cauucugggg agauggugug gaagcggcac agucccuggc aaacagaucu      480

cuaaggggaa ccaaauccgg auucgcuuug uguccgauga guacuucccc agcgagccug      540

gauuuugcau ccauuauaau auuguuaugc cgcaguucac cgaagcugug ucucccuccg      600

uccucccucc cagcgcccug ccucuugacc ugcucaacaa ugccaucacg gcuuuuucua      660

cccuggagga ucuuauuaga uaccuggaac ccgagcggug gcagcucgac cuggaagauc      720

uguaucgccc gacauggcag cuccugggca aagccuucgu guuugggaga aagucccggg      780

uggucgaccu uaaccugcuc accgaggagg uucgccugua cagcuguaca ccuagaaauu      840

ucuccguguc uauccgggag gaacuuaagc gcaccgauac gauuuucugg cccggaugcc      900

ugcucgugaa aagauguggc gggaacugcg cuuguugccu gcacaauugu aacgaaugcc      960

aauguguccc uagcaaggug accaaaaagu aucaugaggu ucugcagcuc cggcccaaaa     1020

caggagugag aggccugcac aagucccuua cagacgucgc ccuggaacac caugaggagu     1080

gcgacugcgu gugucgcggc agcaccgggg gaugaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  6768
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt5)

<400>  6768
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagacuga ucuucgugua cacccucauu ugcgccaacu      120

uuuguagcug ccgggacaca uccgcuacgc cccagucugc cagcaucaag gcgcugcgca      180

augcuaaccu uagacgggau gaccuguauc gcagagauga gaccauucaa gucaaaggca      240

auggguacgu ucaguccccu cgguucccga acucuuaucc ccgcaaucuc cugcuuacau      300

ggagacugca uagccaggaa aacacccgga uccagcucgu guuugacaau caauucggac      360

uggaggaagc cgagaacgau auuugucgcu acgacuuugu ggaagucgag gauaucuccg      420

agacaucuac caucauuaga ggccgguggu gcgggcacaa ggaagugccu ccccgcauca      480

aaagcagaac aaaucagauu aagaucaccu ucaaauccga cgauuauuuu guugccaagc      540

cuggauucaa gauuuacuau agccugcucg aggacuuuca gcccgcugcc gcuucugaaa      600

cgaacuggga guccgugacc agcucuaucu ccggcgucag cuacaauucu ccuuccguga      660

cagauccgac ccugauugcc gacgcgcuug auaaaaagau cgccgaguuc gacacaguug      720

aagaccugcu caaauacuuu aaccccgaga gcuggcagga agaucuggag aauauguauc      780

uugacacccc ucgguaccgc gggagauccu aucaugaucg gaagucuaaa guggaccugg      840

auagacucaa cgacgaugcu aagcgcuaca gcuguacgcc ccggaauuau uccgucaaca      900

ucagagagga acugaagcug gccaacgugg uguucuuucc ucgcugccuc cugguccaac      960

gguguggagg caauugcggc ugugggacag uuaacuggag aagcugcacc uguaauucug     1020

gaaaaacagu gaagaaauac cacgaggugc uucaguucga acccggccau auuaagcgcc     1080

gggggagagc uaaaaccaug gcccuggucg acauccagcu cgaucaccac gagcgcugcg     1140

acugcauuug uuccagccgg ccgccuagau gaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  6769
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt5)

<400>  6769
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugacccaca gcaaguuccc cgccgcuggc auguccagac      120

cucuggacac aucucuccgg cugaaaacgu uuagcuccaa gucugaguac cagcuugucg      180

uuaacgccgu gcgcaaacug caagaaagcg gguucuauug guccgcggug accggaggcg      240

aggcuaaucu ccugcuuucu gccgaaccgg ccgggacauu ucugaucaga gauagcuccg      300

accagcggca uuucuuuacc cucagcguca agacacaguc uggaaccaaa aaccugcgca      360

uucagugcga gggcgggucc uucagccugc aaucugaucc cagauccaca cagccugugc      420

cccgguuuga cuguguucuc aagcuggugc accauuacau gccucccccu ggagcuccga      480

gcuuccccuc uccucccacc gaaccuucca gcgagguccc cgagcagccg uccgcccagc      540

cucuucccgg cucuccuccc cgcagagcuu auuacaucua uagcggcggg gaaaagauuc      600

cccuggugcu cucccggccu cugagcucua auguugccac gcuucaacac cugugccgca      660

aaaccgugaa cggacaucuc gauuccuacg agaaggucac acagcugccg ggccccauca      720

gagaauuucu ggaccaguau gaugcgccuc ucugaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  6770
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt5)

<400>  6770
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugcccagcg ccggccagcu ggcucucuuc gcccugggga      120

ucguccuugc ggcuugccaa gcccuggaga acuccaccuc uccucucagc gccgacccgc      180

ccguugcugc cgcuguggug ucccacuuua augauugucc ugacucucau acacaguucu      240

gcuuucacgg aacguguaga uuccuggucc aggaagauaa gcccgccugc gugugucaua      300

gcggcuacgu uggggcgcgg ugcgagcacg ccgaccuucu ggcugugguc gccgcuuccc      360

agaaaaagca agccauuacc gcgcucgugg uugugucuau cgucgcccug gcugugcuga      420

uuaucacaug ugugcucauu cauugcuguc agguccgcaa acacugcgaa ugguguagag      480

cccugaucug ccggcacgag aagccuagcg cccuucugaa aggacgcacc gcuugcuguc      540

auuccgaaac aguuguguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  6771
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt5)

<400>  6771
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccccuagcg gccugagacu ccugccgcuu cugcuccccc      120

ugcuuuggcu gcucgugcug accccugggc ggcccgccgc uggacugucc acaugcaaga      180

cgaucgacau ggagcucguc aaacgcaaga gaauugaagc cauccggggc cagauucugu      240

cuaaacuucg ccuggcgagc ccucccuccc aaggggaggu uccuccggga ccccucccug      300

aagcugugcu ggcccuuuac aacucuacca gagaucgggu ggccggcgag agcgcugaac      360

ccgagccuga gcccgaagcc gacuauuacg cuaaggaggu cacacgcgug cugaugguug      420

aaacccacaa ugagaucuau gauaaauuca agcaguccac acauucuauu uacauguuuu      480

ucaacaccag cgagcucaga gaagccgugc cggagccugu ccugcugucc cgggcggaac      540

uccgccugcu uagacugaag cucaaagugg agcagcacgu ugaacuguau cagaaguaca      600

gcaauaacuc uuggcgguau cuuuccaauc gccugcucgc ccccagcgac ucuccugagu      660

ggcuguccuu ugaugugaca ggggucguga gacaauggcu gagccgggga ggcgagaucg      720

aaggcuuccg ccucucugcu cauuguuccu gcgacagcag agauaacacc cuucaggugg      780

acaucaaugg guuuacgacc ggacggagag gcgaucuggc cacaauucac gggaugaacc      840

gccccuuccu gcuccugaug gcuacacccc uugagcgggc ccagcaucug caguccucua      900

gacaccgccg ggcgcucgac accaauuacu guuuuagcuc caccgagaaa aacugcugug      960

ucagacaacu guacaucgau uuccgcaagg accugggaug gaaauggauu cacgaaccua     1020

agggcuauca ugccaauuuu ugccucgggc cgugucccua caucuggagc cuggauacgc     1080

aguauucuaa gguucuugcu cuguacaacc agcacaaucc uggagccucc gcugcccccu     1140

gcugugugcc ucaggcccuc gaaccccugc cgauugugua uuacgucggc cggaaaccua     1200

agguggagca acugagcaac augaucguua gaucuugcaa auguagcuga ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  6772
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt5)

<400>  6772
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg ugcugagcgc cuuccucauc cugcaucuug      120

ucaccguugc ucugucccuc ucuacaugua gcacgcugga cauggaucag uuuaugagaa      180

agcggauuga ggccauccgc ggccaaauuc uuuccaaacu gaagcucacc ucucccccug      240

aagacuaucc ggagcccgaa gaggugccuc ccgaagugau cagcauuuac aacuccacaa      300

gagaucugcu gcaggagaaa gcgucucggc gcgcugccgc cugcgagaga gaacggagcg      360

acgaggaaua uuacgcuaag gaggucuaua aaaucgauau gccucccuuc uuuccuuccg      420

agaaugccau cccgcccacc uucuaccgcc cuuauuuuag aauugugcgg uucgacguua      480

gcgcuaugga aaagaacgcc ucuaaucucg ugaaggcgga guuucgcguc uucagacugc      540

agaaccccaa agcccgggug ccugaacagc gcaucgagcu uuaccaaauu cugaagucca      600

aagaucucac aagccccacc cagagauaca ucgacucuaa gguugugaaa acacgggcug      660

aaggggagug gcuguccuuu gaugucaccg acgccgugca cgaguggcuu caucacaagg      720

aucgcaaucu gggauucaag auuagccucc auuguccgug cuguacguuu gugccuucua      780

acaauuauau cauucccaac aaauccgagg aacuggaagc uagauucgcc ggcaucgacg      840

ggaccagcac auacaccucc ggagaucaga agacaaucaa aucuacccgg aagaaaaaua      900

gcggcaagac gccucaucug cuccugaugc uucugcccuc cuauagacuc gagagccagc      960

aaacaaaccg ccggaaaaag agagcgcugg acgccgcuua cugcuuucgc aauguccagg     1020

acaacuguug ccuucggccc cuguauauug auuucaagag agaccucggg uggaaaugga     1080

uccacgaacc uaagggauac aaugccaacu ucugugcugg cgccugcccg uaucuguggu     1140

cuuccgauac ccagcacagc cgcguucugu cucucuacaa uacaauuaac cccgaggcca     1200

gcgcuucccc uuguugcgug ucucaggacc uggagccccu uaccauccug uacuauauug     1260

gcaaaacccc uaagaucgaa caacucagca acaugaucgu gaaauccugc aaguguagcu     1320

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  6773
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt5)

<400>  6773
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacc uucagagagc ccucgugguc cuggcucugc      120

ugaacuucgc caccguuagc cucucccugu cuacaugcac gacccuugac uuuggccaua      180

ucaaaaagaa acggguggag gcgauucgcg ggcaaauccu gagcaagcuc agacugacau      240

cucccccuga accgaccgug augacacacg uccccuacca ggugcuggcu cucuauaauu      300

ccacccggga gcugcuugaa gagaugcaug gagaacgcga ggagggcugu acacaggaaa      360

acaccgagag cgaauacuau gccaaagaga uucacaaguu cgauaugauc caggggcugg      420

ccgagcauaa ugaacucgcu guuugcccua agggaauuac guccaaagug uuuagauuca      480

acgucucuag cguggagaag aaucggacca accuguuucg cgccgaguuc agaguucuuc      540

gggugcccaa uccuuccagc aaacgcaacg aacaaagaau cgaacuguuu cagauccucc      600

ggcccgacga gcacauugcu aagcagcgcu acaucggcgg gaaaaaucug ccuacaagag      660

gaaccgccga guggcugucu uucgauguca cagacaccgu gcgggaaugg cuccugcgca      720

gagaguccaa ccuuggccug gaaauuagca uccacugucc gugccauacg uuucagccca      780

auggcgauau ucucgagaac auccacgaag ugauggagau uaaguucaag ggggucgaca      840

augaggauga ccauggacgg ggcgaucugg ggagacuuaa aaagcaaaaa gaccaccaca      900

acccucaucu gauccucaug augauucccc cucaccgccu ggauaauccc ggacagggcg      960

ggcagcggaa gaaaagagcg cuggacacaa acuauuguuu ucgcaaccuc gaagagaauu     1020

gcuguguucg gccgcuguac aucgauuuca gacaggaccu uggauggaag ugggugcaug     1080

aaccuaaagg cuauuacgcc aacuuuugcu cuggccccug uccuuaccug cgcuccgcug     1140

acaccacaca cagcaccgug cucgggcugu auaauacccu uaaccccgag gccucugcuu     1200

cccccugcug ugucccucaa gaucuggaac cgcucacaau ccuguacuau gugggacgga     1260

cgcccaaggu ugagcagcug agcaauaugg uggucaaguc cugcaaaugc ucuugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6774
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt5)

<400>  6774
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccccgugg cugucugggc cgcgcuggcu guuggccucg      120

agcugugggc cgccgcucac gcccuuccug cucagguggc cuucaccccg uacgcgcccg      180

aaccugggag cacaugcaga cugcgggagu auuacgacca aacggcccag auguguugcu      240

ccaaguguuc ucccggacag caugcuaaag uguuuugcac caagacaagc gauaccgucu      300

gugacuccug cgaagauucu acauauaccc agcucuggaa cugggugccu gagugucuga      360

gcugcggcuc ccgcuguucu agcgaccaag uugaaacaca ggccugcacc agagagcaga      420

aucggaucug uacgugccgc cccggguggu acugcgcucu uuccaaacag gagggaugua      480

gacugugcgc cccucuccgg aagugucgcc cgggcuucgg gguggcgaga cccggaaccg      540

aaacaagcga ugucgugugc aaaccuugug cccccggcac cuuuucuaac acaaccucca      600

gcacggacau uugccggccu caccaaaucu guaauguugu ggcuauuccc ggcaacgccu      660

cuauggaugc ugucugcaca uccaccagcc cgacacgcuc uauggccccu ggggccgugc      720

aucugcccca gccugugucc accagaagcc agcacaccca gcccacaccc gagccuucca      780

cggcuccguc uaccagcuuc cugcucccca ugggaccuuc cccucccgcg gaaggcagca      840

caggggacuu ugcccugccc gucggacuua ucguuggcgu gaccgcucug gggcuccuga      900

uuaucggagu ggucaauugu gugaucauga cacaaguuaa gaagaaaccg cuuugccugc      960

agcgggaggc caaggugccu caucuccccg ccgauaaagc ucgcggcacc cagggcccug     1020

agcaacagca ucugcugauu acggcccccu cuuccagcuc uagcucccuc gaaucuagcg     1080

cguccgcucu ggacagacgg gccccuacac gcaaccagcc ccaggccccg ggggucgagg     1140

cuagcggagc cggcgaagcu agagccucua ccggguccag cgauucuucc ccuggaggcc     1200

acgggaccca agugaauguu acauguaucg ugaacgucug cagcuccucu gaccacagcu     1260

cccagugcuc uagccaggcg uccagcacca ugggagauac agacucuucc cccagcgagu     1320

cucccaagga cgaacaggug ccuuucucca aagaggagug ugccuuucgg agccaacuug     1380

aaacgccgga gacccugcuc ggcucuacag aagagaagcc ccugccucuu ggcguccccg     1440

augcugggau gaagccuagc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  6775
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt5)

<400>  6775
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgugauga gacuguuccc uugcuuucuc cagcugcuug      120

ccggccuggc ucucccggcc guucccccuc aacagugggc gcugagcgcu gggaacggau      180

ccucugaggu cgaaguggug cccuuccagg aggucugggg ccggagcuac ugucgcgccc      240

uugaaagacu gguggacguu guguccgagu auccuucuga agucgagcac auguuuagcc      300

ccuccugcgu gucucuccug cgguguaccg ggugcugugg agaugagaau cugcauugcg      360

uuccugugga aacagccaac gucacgaugc agcuccugaa gauccgcagc ggcgacagac      420

cguccuacgu ggagcuuacc uucagccaac acgugcggug ugaaugccgc ccccugagag      480

agaaaaugaa gccugagcgg cgcagaccca aagggcgggg aaagcgcaga cgggaaaaac      540

agcgcccuac agauugucau cucugcggcg acgcuguccc cagacgguga ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  6776
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt5)

<400>  6776
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgacagac agacagauac ggcccccagc ccuuccuacc      120

accuucuccc gggccggcgc agaaccgugg acgcugccgc gucucggggg caaggacccg      180

agccugcucc cggcggggga gucgaaggcg uuggggcccg cggaguggcc cugaagcugu      240

ucgugcagcu gcucggcugc agcagauuug gcggggcugu cgugcgggcc ggagaggcug      300

aaccuuccgg cgccgcgcgc ucugccagcu ccgggagaga ggaaccccag ccugaggagg      360

gagaagagga agaggagaaa gaagaggaac ggggcccgca guggcgccug ggggcuagaa      420

agcccggauc uuggacaggc gaggccgcug uuugugccga uagcgcgccu gccgcucggg      480

cuccccaagc ccuugcccgc gccuccggca gagggggacg gguggcucgc agaggcgcgg      540

aagagagcgg gccuccccau ucuccguccc ggagaggaag cgccucucgc gcuggcccug      600

ggcgggccuc cgagaccaug aacuuccugc ucagcugggu ccacuggucu cuggcccugc      660

uccuguaucu ucaucacgcu aaaugguccc aggccgcgcc cauggcugaa ggaggcggcc      720

agaaucauca cgaggugguu aaguuuaugg acguguacca gagaagcuau ugccacccua      780

ucgaaacacu ggucgauauu uuccaagagu accccgacga aaucgaguau auuuuuaaac      840

ccuccugugu gccucucaug cgcugcgggg gauguugcaa cgaugagggc cuggaaugug      900

ugccgaccga ggaaucuaau aucacaaugc agauuaugcg gaucaagccc caucaggggc      960

agcacaucgg agagaugagc uuccuucaac auaacaagug cgaauguaga ccuaaaaagg     1020

accgcgcccg gcaggagaaa aaguccguca gaggcaaagg gaagggccag aagcgcaaac     1080

ggaagaaaag cagauacaag ucuugguccg uuuauguggg agcccgcugc ugucugaugc     1140

ccuggagccu cccuggcccc cacccgugcg ggccuugcuc ugagcggaga aaacaccugu     1200

uugugcaaga uccccagacc uguaagugca gcuguaaaaa uacggacucc cggugcaagg     1260

cucgccagcu ggaacucaac gagagaaccu gucggugcga uaagccuaga cgcugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6777
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt5)

<400>  6777
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggucc cuggcccuuc      120

ugcucuaccu gcaucacgcu aaguggucuc aggccgcgcc cauggcugag ggcgggggac      180

aaaaucauca cgaagucguu aaauuuaugg acguguauca gagaagcuac ugccauccua      240

ucgagacccu uguggauauu uuccaggaau auccggacga gaucgaauac auuuuuaagc      300

ccuccugugu cccucugaug cggugcggcg gguguugcaa cgaugaggga cucgagugug      360

ugcccacaga agagucuaau aucacgaugc agauuaugcg caucaaaccu caccaaggcc      420

agcacaucgg ggaaaugagc uuccugcagc auaacaagug cgaguguaga cccaaaaagg      480

accgggcccg ccaggagaag aaauccguua gaggaaaggg caaaggccaa aagcggaaac      540

gcaagaaguc uagauauaaa agcugguccg uguacgucgg ggcccggugc ugucugaugc      600

cuuggagccu cccgggaccc cacccuugcg gccccuguuc ugaacgcaga aagcaucugu      660

uugugcagga uccucagacc ugcaaaugcu ccuguaagaa uacagacagc cggugcaaag      720

cucgccagcu ugagcugaac gaaagaaccu gucggugcga uaagccccgc agaugaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  6778
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt5)

<400>  6778
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcccccugc ucagacggcu gcuucuggcc gcucuccugc      120

agcuugcccc ugcgcaagcu ccgguguccc agcccgacgc cccuggccac cagcgcaagg      180

ucguuucuug gaucgaugug uacaccagag ccacaugcca gccccgggag guggucgugc      240

cucugacggu ugaacucaug gggaccgugg cuaagcaacu gguccccagc ugugugacag      300

uucagcgcug cggaggcugu ugcccugacg augggcugga gugugugccg accggacagc      360

aucaggucag aaugcaaauu cucaugaucc gguaucccuc cucucagcug ggcgaaauga      420

gccuugagga acacucccag ugcgaguguc gcccuaagaa aaaggacucu gccgugaaac      480

ccgauagagc ugccacaccu caucaccggc cccagccgcg cagcgugccu gggugggacu      540

ccgcgcccgg agccccuagc cccgcugaua uuacccaucc caccccugcc ccgggccccu      600

cugcucacgc cgcgccuucc acaacgagcg cccugacccc cggcccugcu gccgcugccg      660

ccgacgcugc ggccucuucc gucgcuaaag ggggagccug aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  6779
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt5)

<400>  6779
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caucugcucg gcuucuuuag cguggccugc ucccugcuug      120

cugccgcgcu gcuccccggg ccuagagagg cuccggccgc cgcugccgcu uucgaaucug      180

gacuggaccu uagcgaugcc gagcccgacg cgggcgaagc caccgcuuac gccuccaagg      240

aucuggagga acagcuccgg ucugucagcu ccguugacga gcugaugaca gugcuguauc      300

cugaguacug gaaaauguau aagugucaac uccgcaaagg gggauggcag cacaacagag      360

aacaggcuaa ucugaacucu cggacggagg aaaccaucaa guuugccgcg gcccacuaca      420

auacagagau ucuuaaaagc aucgauaacg aguggcgcaa gacccagugc augcccagag      480

aaguguguau ugacgucggc aaggaguucg ggguggcuac aaauaccuuu uucaaaccuc      540

ccugcguuuc cguguaucgg uguggaggcu gcuguaacag cgaaggccug caaugcauga      600

auacaucuac cuccuaccuc agcaagacgc uguuugagau caccgucccu cuuucucagg      660

ggccgaaacc cgugacaauu uccuucgcca accauaccag cugucgcugc augucuaagc      720

uggauguuua uagacaggug cacuccauca uccggcgcag ccucccugcu acacugcccc      780

agugucaagc cgccaauaaa accugcccua cgaacuacau guggaauaac cauauuugca      840

gaugucuggc ucaggaagac uuuauguucu ccucugaugc gggagacgau agcacagacg      900

gcuuucacga uaucugcggg cccaauaagg agcucgacga ggaaaccugu cagugcgucu      960

gucgggccgg acugcgcccg gcuuccugcg gcccucacaa ggagcuugac agaaacagcu     1020

gucagugcgu guguaaaaau aagcuguucc ccucucaaug cggggccaac cgggaauuug     1080

augagaacac augucagugc gugugcaaac gcaccugucc uagaaaucag ccccucaacc     1140

ccggaaagug cgccugugaa ugcaccgagu ccccucaaaa augucugcuu aagggcaaaa     1200

aguuccauca ccagacaugc agcuguuacc ggagaccgug cacgaaucgc cagaaggcuu     1260

gugagcccgg cuucucuuau agcgaagagg ucugccggug uguuccuucc uacuggaaaa     1320

gaccccagau gucuugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  6780
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt5)

<400>  6780
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagagu ggguggucgu uaacguguuc augaugcugu      120

augugcagcu cguccaaggc agcuccaaug aacacgggcc cgugaagcgg ucuagccagu      180

ccacccugga gcgcucugaa cagcagauca gagccgcuag cucccuugag gaacugcucc      240

ggauuacaca uucugaggac uggaaacugu ggcgcugcag acuucggcuc aagagcuuua      300

cguccaugga uagccgcucu gccucccaca gaagcacccg guucgcggcu acauuuuacg      360

acaucgagac ccugaaaguu auugaugaag aguggcaacg cacacagugu ucuccuagag      420

aaaccugcgu ggaggucgcc uccgagcugg gaaagagcac aaacaccuuc uuuaaaccgc      480

ccugugugaa uguuuuccgg ugcggcgggu guugcaacga agagucucug aucuguauga      540

auacguccac cagcuauauu uccaagcagc ucuuugaaau cucugugccu cugacaagcg      600

uccccgagcu ugugccugug aaggucgcca accauaccgg augcaaaugu cugcccacag      660

cuccucgcca cccguacucc aucauuagac ggagcaucca gauucccgaa gaggaccgcu      720

gcucucauuc caagaaacuc uguccuaucg auaugcugug ggacagcaau aagugcaaau      780

gcguucuuca agaggaaaac ccccuggccg gcaccgagga ucacucucac cuccaggaac      840

cugcucugug ugggccccau augauguucg acgaggauag augcgaaugu gugugcaaga      900

cgccgugucc uaaggaccug auucagcacc ccaaaaauug cagcuguuuu gagugcaagg      960

agucccucga aacauguugc cagaaacaua agcuguucca cccugauacc uguucuugcg     1020

aggaccggug ccccuuucac acaagacccu gugccagcgg aaaaaccgcg ugcgccaagc     1080

auugucgcuu cccuaaagaa aagcgggcug cccaaggccc gcacuccaga aagaaccccu     1140

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  6781
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt6)

<400>  6781
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucagacg aaacaggauu ugaacacuca ggauuauggg      120

uaucaguauu agcaggauua cuacucggag caugccaagc acacccaauc ccagacucau      180

caccauuauu acaauucgga ggacaaguca gacaacgaua cuuauacaca gacgacgcac      240

aacaaacaga agcacauuua gaaauaagag aagacggaac aguaggcgga gcagcagauc      300

aaucaccaga aucacuacua caacuaaaag cacuaaaacc aggaguaaua caaauauuag      360

gaguaaaaac aucaagauuc uuaugccaaa gaccagacgg agcacuauac ggaucauuac      420

acuuugaucc agaagcaugc ucuuucagag aacuacuacu agaagacgga uacaacguau      480

accaaucaga agcucaugga cuaccuuuac accuaccagg aaacaaauca ccacacagag      540

auccagcucc cagaggaccc gcaagauucc uaccauuacc aggauuacca ccagcauuac      600

cagaaccacc aggaauacua gcaccacaac caccagacgu aggaucauca gacccauuau      660

caaugguagg accaucacaa ggaagaucac caucauacgc aucauaagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  6782
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt6)

<400>  6782
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacucauuuc caccacuauu auuacuacua uuuuggggag      120

ucguaucaca uagcuuuccc gcaacacuag aaacccaaga acaagacgua gacuuaguac      180

aaaaauaucu agaaaaauac uauaaccuca aaaacgacgg aagacaaguc gaaaaaagaa      240

gaaacagcgg accaguugua gaaaaacuaa aacaaaugca agaauuuuuc ggauuaaaag      300

uuacuggaaa accagacgca gaaacacuaa aaguaaugaa acaaccaaga ugcggaguac      360

cagauguagc acaguucgua uuaacagaag gaaacccacg uugggaacaa acacaucuua      420

cauacagaau ugaaaauuac acaccugacc uaccaagagc agacguagac cacgcaauag      480

aaaaagccuu ucaauuaugg ucaaacguaa caccauuaac auucacaaaa guuucugaag      540

ggcaagcaga cauaaugauc ucauuuguua gaggagacca ccgagacaau agcccauucg      600

acgggccagg aggaaaccua gcacaugcuu uccaaccagg accuggaaua ggaggcgacg      660

cacauuucga cgaagacgaa cgauggacaa acaauuucag agaauacaac cuacauagag      720

uagcagccca cgaauuaggc cacagccuag gcuuaucaca cucaacagac auuggagcuc      780

uaauguaccc uuccuacaca uuuucaggag acguacaauu agcccaagac gauauagacg      840

gaauacaagc aauauacgga cgaucacaaa acccaguaca accaauagga ccacaaacac      900

caaaagcaug cgacucaaaa uuaacauuug acgccauaac aacaauaaga ggagaaguaa      960

uguuuuucaa agaccgauuu uauaugagaa caaauccauu cuacccagaa guagaauuaa     1020

acuuuauaag uguauucugg ccucaauuac caaacggauu agaagcagca uaugaauuug     1080

cagacagaga cgaaguacga uucuuuaaag gaaauaaaua cugggccgua caaggacaaa     1140

acguauuaca uggauaccca aaagacauau acagcucauu cggguuucca agaacaguaa     1200

aacacauaga cgccgcauua ucagaagaaa acacaggcaa aacauauuuu uucguagcaa     1260

acaaauacug gagauacgac gaauacaaaa gaucaaugga cccaggauau ccaaaaauga     1320

uagcacacga uuucccuggc auugggcaca aaguagaugc aguauucaug aaagauggcu     1380

uuuucuacuu cuuucacgga acucgacaau acaaauucga cccaaaaaca aaaagaauac     1440

ucacacuaca aaaagcaaac aguugguuca auuguagaaa aaacuaagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  6783
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt6)

<400>  6783
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauucauucc caccacuacu auuauuauua uucuggggag      120

uaguaucaca uucauuugua cuaacugaag gaaauccuag augggaacaa acucacuuaa      180

ccuauagaau agaaaacuau acaccagacc uaccaagagc cgacgucgac cacgcaauug      240

aaaaagcauu ccaauuaugg aguaacguaa caccacuaac auucacaaaa guaucagaag      300

gacaagcaga cauaaugaua ucauuuguca gaggagacca ccgagacaac ucaccauuug      360

acggaccugg aggaaaucuc gcacacgcau uccaaccagg accaggaaua ggaggagacg      420

cacauuuuga ugaagaugaa cgauggacca acaauuuuag agaauacaac cuacaccgag      480

uagccgcaca cgaacucgga cacagccuag gacuaucaca cucaaccgac aucggagcac      540

uaauguaccc aucauacaca uucuccggag acguccaacu agcucaagac gacauagacg      600

gaauacaagc aauauacgga agaucacaaa auccuguaca accaauagga ccacaaaccc      660

caaaagcaug cgacucaaaa uuaacauuug acgcaauaac cacaauuaga ggugaaguaa      720

uguuuuucaa agauagauuu uacaugagaa caaaucccuu cuauccagaa guagaauuaa      780

auuucauauc aguauucugg ccacaacuac caaauggauu agaagcagca uacgaauuug      840

cagauagaga cgaaguaaga uucuucaaag gcaacaaaua cugggcagua caaggccaaa      900

acguacuaca cggauauccu aaagacauau acucuuccuu uggauuuccu agaacaguaa      960

aacacauaga ugccgcacua ucagaagaaa acaccggaaa aacauacuuc uucgucgcca     1020

auaaauacug gagauacgac gaauauaaac gaucaaugga cccagguuac ccaaaaauga     1080

uagcacacga uuucccagga auaggacaca aaguugacgc agucuuuaug aaagacggau     1140

uuuucuacuu cuuucacgga acacgacaau acaaauucga ucccaaaacu aaaagaaucc     1200

uaacuuuaca aaaagccaau ucuugguuua auuguagaaa aaacuaagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  6784
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt6)

<400>  6784
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaaaaaca uacucaaaau ucuaauggac ucauacucga      120

aagaaucaaa aauacaaaca guccgcagag uuacaucagu cucguuacua gcaguauacc      180

ugacgaugaa cacauccucg uuaguacucg cuaaaccuau agaaaauacc aacgauacca      240

guauaaaaaa cguagaaaaa uuaagaaaug caccaaacga agaaaacagu aaaaaaguag      300

aagacaguaa aaaugacaaa guagaacaug uaaaaaacau agaagaagca aaaguugaac      360

aaguagcacc agagguaaaa uccaaaagca cauuaagaag cgcgucaauc gccaacacaa      420

auucagagaa guacgacuuc gaauacuuaa acggauuaag uuauacagaa cuaacaaauc      480

ucauuaaaaa uaucaaaugg aaccagauaa auggacuauu uaauuacuca acaggaucac      540

aaaaauuuuu cggagacaaa aauagaguac aagcaauuau aaacgcuuua caagaaagcg      600

gacgaacgua uacagcaaac gauaugaaag gaauugaaac auucacagaa guacuacgcg      660

cugguuuuua ucugggcuau uauaacgacg gacuaucaua ccucaacgac cgaaacuucc      720

aagauaaaug cauaccagcg augauugcaa uucaaaaaaa cccaaacuuu aaacuaggaa      780

ccgcagucca agaugaagua auaacgucgc ucggaaaacu aauaggaaau gcaagcgcua      840

augcagaagu uguaaauaac uguguucccg uacuaaaaca auuccgagaa aauuuaaauc      900

aauacgcacc agauuacguc aaaggaacgg ccguuaauga acuuaucaaa ggaauagaau      960

uugauuucuc aggagcagcu uaugaaaaag acguaaagac uaugccaugg uacggaaaaa     1020

uagaucccuu uauaaaugag cugaaggcac uaggccuuua cggaaacauc acaucagcua     1080

cagaaugggc gucagauguc gggauauacu aucuaucaaa auucggacuu uacucaacca     1140

accgaaauga uauaguacaa uccuuagaaa aagcaguaga uauguauaaa uacggaaaaa     1200

uagcuuucgu cgcaauggaa cgaaucacau gggauuauga cgguauagga agcaauggaa     1260

aaaaaguaga ucaugacaaa uuccuagaug acgcagaaaa acauuaccuc cccaaaacau     1320

acaccuucga uaacggcaca uucauaauaa gagcuggaga caaaguauca gaagaaaaaa     1380

ucaaacguuu auacugggca ucacgagagg uuaaaucaca auuccauaga guagucggua     1440

augacaaagc auuagaagua ggcaaugcag acgacguacu cacaaugaaa auauucaauu     1500

cuccugaaga auauaaauuu aauaccaaca uuaacggagu aucuacagac aauggaggcc     1560

uuuacauaga accaagagga acguucuaua ccuacgaaag aacaccacaa caaucaaucu     1620

uuucauuaga agaacuauuu agacacgaau acacacacua ucugcaagca cgauaccugg     1680

uggauggacu auggggacaa gggccauuuu augaaaaaaa ccgcuuaaca ugguuugaug     1740

aaggcacagc cgaauuuuuc gcaggaucaa ccagaacauc gggugucuua ccacggaaau     1800

caauacucgg guacuuagca aaagacaaag uagaucauag auauucauua aaaaaaacac     1860

uaaauagugg auaugaugac ucggauugga uguuuuacaa cuaugguuuu gcgguagcac     1920

auuauuuaua ugaaaaagau augcccacau ucauaaaaau gaacaaagcu auauuaaaua     1980

ccgauguaaa gagcuaugau gaaauaauaa aaaaacucag ugaugaugca aauaaaaaca     2040

cugaauauca aaaccacaua caagaacuag cagacaaaua ccaaggagca gguauuccgu     2100

uaguuucaga ugauuacuua aaagaccacg gauauaaaaa agcaucagaa guauacagug     2160

aaauaucgaa agcagccagc cuuacaaaca ccucaguaac agcagagaaa agucaauauu     2220

ucaacacauu uacacuaaga ggaacauaca cgggggaaac cucaaaagga gaauuuaaag     2280

auugggauga aauguccaaa aaacuagacg gaacacuaga gagcuuagcu aaaaacaguu     2340

ggagcggaua caaaacuuua acggcauacu uuacuaacua ccgaguuaca agugacaaua     2400

agguucaaua cgacguagua uuucacggag uacuaacaga caacgcugau auuaguaaca     2460

acaaagcgcc uaucgcuaaa guaacaggac caucgacugg ggcagucgga aggaacauag     2520

aauuuucugg gaaagacagu aaagaugaag acggaaaaau aguuaguuac gauugggauu     2580

uuggcgaugg agcuaccucu cguggaaaga acucugugca ugcauacaaa aaagcaggaa     2640

cauauaacgu aacccuaaaa guaacagacg acaaaggagc aacagcuaca gagagcuuua     2700

ccauagaaau aaaaaacgaa gauacaacga caccaauaac aaaagagaug gaaccuaaug     2760

augacauaaa agaagcuaac ggacccauag uggaaggagu aacagugaaa ggagaccuga     2820

auggcagcga ugacgcugau acuuuuuauu ucgaugucaa agaagacggu gacguaacca     2880

uugaacuacc guacagcggc aguucaaauu uuacaugguu gguauauaaa gaaggagacg     2940

accaaaacca cauagcaucu ggaauagaua aaaauaacuc aaaaguuggu acauuuaaaa     3000

guacaaaagg uagacacuau guauucaucu auaaacacga cagcgcauca aacauauccu     3060

auucccucaa uauaaaggga cuaggaaaug aaaaacugaa agaaaaagaa aauaacgauu     3120

ccagugacaa agcaacugua aucccaaauu uuaauacaac aaugcaagga ucuuuauuag     3180

gagacgauag ucgcgacuau uacucauuug aagugaaaga agaaggagaa guaaauauag     3240

aacuugacaa aaaagacgag uucggaguaa ccuggacucu ccacccagaa ucaaauauaa     3300

acgauagaau cacauacgga caaguagacg guaacaaagu cucaaauaag guaaaacuua     3360

gaccagggaa auacuauuua cucguauaua aauacucugg cagcggcaac uacgaguuac     3420

ggguuaacaa auaaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  6785
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt6)

<400>  6785
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguca ccuuuauaag ucuacuuuuc uuauuuuccu      120

cagcauauag cauagcaaau acaaauuccg aaaaauauga cuucgaauac cuaaacgguc      180

uuaguuacac agaauuaacu aaccuaauua aaaacauaaa auggaaucaa auaaauggcu      240

uauuuaauua uucaacaggu agucaaaaau ucuucggaga uaaaaacaga gugcaagcaa      300

uaauaaacgc ccuacaagag ucaggacgaa cauauacagc aaaugacaug aaaggaauag      360

agacauucac agagguauua cgugccggau ucuaccuagg auacuacaac gacgguuuau      420

cuuacuuaaa ugacagaaac uuccaggaua aauguauacc agcaaugaua gcaauacaga      480

aaaacccuaa uuucaaacuc ggaacggcgg uucaagacga aguaauuaca ucuuuaggua      540

aauugauagg aaacgcauca gcgaacgccg agguaguaaa caauugcgua ccgguccuua      600

aacaauuuag agaaaaucua aaccaauaug caccagacua cgugaaagga acagcaguga      660

augaauuaau aaaaggcauu gaguucgacu ucucaggagc agcauaugaa aaagauguaa      720

aaacaaugcc augguacgga aaaauagauc cauucauaaa ugaacuaaaa gcauuaggau      780

uauacggcaa caucaccagu gcaacugaau gggcaucaga ugucgggaua uacuauuuau      840

caaaauucgg acucuauagc acaaaccgaa acgacauagu acaaucacua gagaaagcag      900

uagacaugua caaauacggg aaaauagcau uuguagccau ggaacgaauu acaugggacu      960

acgauggcau agguagcaau ggaaagaaag uagaucacga uaaauuccuu gacgacgcag     1020

aaaaacacua ucuuccuaaa acauacacuu uugauaacgg uaccuucaua auacgagccg     1080

gugauaaagu aagcgaagag aaaauaaaaa ggcuauauug ggcaagcaga gaagucaaaa     1140

gccaauuuca uagaguagua ggaaaugaca aagcacuaga aguuggaaac gcugacgaug     1200

uucuaacaau gaaaaucuuc aacucaccug aagaauacaa auucaacaca aacauaaaug     1260

gaguaaguac cgacaacgga ggauuauaua uagaacccag ggggacguuu uauaccuacg     1320

agagaacccc ucaacaaucu auauuuuccu uagaagaauu auuucgacau gaauacacac     1380

acuauuuaca agcacgauau uugguagaug gacuaugggg acaaggacca uuuuaugaga     1440

aaaacagacu uacgugguuc gacgaaggaa cggcagaguu cuuugcagga aguacaagaa     1500

caaguggagu auuaccaaga aaaucaauac uagguuacuu agcaaaagac aaaguagauc     1560

acagauacag ccuaaagaaa acacugaaua gcgguuauga ugacagugau uggauguucu     1620

auaauuacgg auucgcagua gcucacuauc uauaugaaaa agauaugcca acauucauca     1680

aaaugaauaa agcaauacuu aacaccgacg uuaaaucaua ugacgaaaua auaaagaaau     1740

uaagugacga cgcaaacaaa aauaccgaau accaaaacca cauccaagaa cuagcagaca     1800

aauaucaagg ugcaggaaua ccauuaguau cagacgacua ccucaaagac cauggauaca     1860

agaaagcguc cgaaguauac ucagaaauaa guaaagcagc aucauugacu aauacuucag     1920

uaacagcaga aaaaucacaa uacuuuaaca cauucacacu ucgcggaaca uauacgggag     1980

aaaccucaaa aggugaauuu aaagauuggg acgaaaugag uaaaaagcuc gacggcacuc     2040

uagaaucauu ggcuaaaaac uccuggucag gauauaaaac acuaacagcc uacuucacca     2100

auuacagagu caccucagau aauaaaguac aauaugacgu aguauuucau ggagucuuaa     2160

cagacaacgc ugauauaagu aacaauaaag cgccuauagc gaaaguaaca ggaccaucaa     2220

cgggagcagu aggaagaaau auugaguucu caggaaagga uagcaaagac gaagacggaa     2280

aaauuguauc uuaugauugg gauuucggag auggagcaac cucaagaggg aaaaacagug     2340

ugcaugccua caagaaagca ggaacuuaua auguaacacu aaaagugaca gaugacaaag     2400

gagcgacagc aacagagagc uucacgauug aaauuaaaaa cgaagauacu acaacaccca     2460

uaacaaaaga aauggaacca aaugaugaca uaaaagaagc aaacggaccg auaguggaag     2520

gcguaacggu aaaaggagac uuaaauggaa gugaugacgc cgacacauuu uacuuugaug     2580

uuaaagaaga cggugauguc acaauagaau uacccuacuc ugguaguucc aacuucacuu     2640

gguuaguaua caaagaagga gaugaucaaa aucauauagc auccggaaua gacaaaaaca     2700

auagcaaagu aggcacauuu aaauccacaa aaggacguca uuauguuuuc auuuacaaac     2760

acgauagugc aaguaacaua aguuauucuc uaaauauaaa aggacuaggu aaugaaaaac     2820

uaaaagaaaa agaaaacaac gauagcagug acaaagcuac uguuauccca aacuucaaca     2880

ccacaaugca aggcagcuua cucggagacg auucacgaga uuauuacagc uucgaaguaa     2940

aagaagaggg ggaaguaaac auagaacuag auaagaaaga cgaauuugga guaacaugga     3000

cacuacaccc ggaaucgaac auaaaugaca gaaucacaua uggacaagua gacggaaaca     3060

aaguaucaaa uaaagucaaa cuaagaccug gcaaauauua ccuauuagug uauaaauauu     3120

caggaucagg uaauuacgaa cugagaguca auaaauaagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  6786
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt6)

<400>  6786
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguaa cuuucauaag ucuucuuuuc cuuuucucuu      120

cagcauacuc gaugaagaaa aacauacuaa aaauacucau ggauuccuau agcaaagaaa      180

guaaaauaca aacaguacgg agaguuacau caguaagucu auuagcagua uaccuaacaa      240

ugaauacaag cuccuuagua uuagcaaagc caaucgaaaa cacaaacgau acgucaauua      300

aaaacguaga aaaauuacga aacgcaccua augaagaaaa cucaaagaaa gucgaagaca      360

gcaaaaacga uaaagucgag cacgugaaaa auauagaaga agcaaaagua gaacaaguag      420

ccccagaagu aaaaaguaaa ucaacucuaa gaucugcuuc acgcagacga cguaaacgaa      480

uagccaacac aaauucagaa aaauaugauu ucgaauaccu aaacggguua ucauacacag      540

agcuaacgaa ucuaaucaaa aacauaaaau ggaaccaaau aaauggccua uuuaauuaua      600

gcacaggauc ccaaaaauuc uucggcgaca aaaaucgagu acaagcaaua auuaaugcac      660

uacaggaauc uggcagaaca uauacugcua augacaugaa aggaauagaa acauuuacag      720

aaguacucag agcaggauuu uauuuagguu auuauaauga cggcuuaagu uaccuaaaug      780

auagaaacuu ucaagauaaa ugcauaccug caaugaucgc aauacagaaa aacccaaacu      840

uuaaacuagg gacagcggua caagacgaag uaauaaccag cuuaggaaaa cucaucggaa      900

acgcuucugc aaacgcggaa guuguaaaca acugcguacc aguacuaaaa caauuccgag      960

aaaaccuaaa ucaauacgcu ccagauuaug uaaaaggaac ggcuguaaac gaauuaauaa     1020

aagguaucga auuugauuuc agcggcgcag ccuaugaaaa ggacgucaaa acgaugccau     1080

gguauggaaa aauagaccca uucauaaaug aacugaaagc acucggacuu uacgguaaua     1140

uaacaagugc uacagaaugg gcaucagacg uaggaauaua uuauuuauca aaauucggau     1200

uauacucaac aaauagaaau gacauaguac aaagucuaga aaaagcgguc gacauguaca     1260

aauauggcaa aauagcauuu guagcuaugg aacgcauaac augggacuau gauggaauag     1320

guucuaacgg uaagaaaguu gaucaugaua aauucuuaga ugacgcagaa aaacacuacu     1380

uaccaaaaac auauacauuc gacaacggca ccuuuauaau acgugccgga gacaaaguua     1440

gugaagagaa aauuaaacga cuauacuggg cuucgagaga aguaaaaucu caauuucaca     1500

gagucguggg aaacgauaaa gcacuagaag uuggaaacgc agaugauguc cucacaauga     1560

aaaucuuuaa uuccccggaa gaauacaaau uuaauacgaa uaucaacggc gugucaacug     1620

auaauggagg acuguauaua gaaccacgag gaacauucua cacuuaugaa agaaccccgc     1680

aacaaagcau uuucucccua gaagaacuau ucaggcauga auauacacau uaccuccaag     1740

ccagauaccu aguugaugga cuauggggac aaggaccguu uuacgagaaa aaucgauuaa     1800

ccugguuuga ugaaggaacg gcagaguucu uugcaggauc aacaagaaca agcggaguac     1860

uaccaagaaa auccauacua gguuacuuag caaaagauaa aguugaccac agauauaguu     1920

uaaagaaaac ccucaacagu gguuacgaug auucggauug gauguuuuac aacuacggau     1980

ucgcaguugc gcacuacuua uacgaaaaag auaugccaac guucauaaaa augaacaaag     2040

caauacuaaa uacugauguc aaaagcuacg augaaauaau aaagaaacua agugacgacg     2100

ccaauaaaaa uacagaauac caaaaccaua uacaagaacu agcugacaaa uaccaaggug     2160

cgggaauacc ucuaguaagu gacgacuauc uaaaagauca uggauauaag aaagcaucag     2220

aaguuuacuc ugaaaucagc aaagccgcau cauuaacaaa caccucagua acagcugaaa     2280

aaucacaaua uuucaacaca uucacacuaa gggguacaua uacaggcgaa accaguaaag     2340

gagaauuuaa agauugggac gaaaugagca agaaauuaga uggaacucua gaaucuuuag     2400

ccaaaaacuc uuggucagga uacaaaacau uaacggcaua uuucacgaac uauagaguua     2460

caagugauaa uaaagugcaa uaugacguag uauuucacgg aguccucaca gauaacgccg     2520

auauuucaaa uaauaaagcu ccgauagcua aaguaaccgg uccauccaca ggagcaguag     2580

gcagaaacau ugaguucucu gguaaagaua guaaagauga agauggaaaa auagucucau     2640

acgacuggga uuucggagau ggagcaacau caagagggaa aaacucagua caugccuaua     2700

agaaagcggg aaccuauaac guaacccuaa aagucacaga ugacaaggga gcaacggcua     2760

cagaaaguuu uacaaucgaa auuaaaaaug aagacacaac aacaccaaua acgaaggaaa     2820

uggaaccaaa cgacgacauc aaagaagcua acggaccaau aguugaagga guaacaguua     2880

aaggagauuu aaacggauca gaugaugcgg acacuuuuua cuucgauguc aaagaagaug     2940

gagacgucac cauugaauua ccuuauucag gaagcaguaa cuucaccugg uuaguauaua     3000

aagaaggaga cgaucaaaac cacaucgcua gcggcauaga uaaaaauaau ucaaagguug     3060

gaaccuuuaa gucaacaaaa ggaagacacu auguauuuau cuacaaacau gauuccgccu     3120

caaacauauc cuauagccug aauaucaaag gccuaggaaa cgaaaaauua aaagaaaaag     3180

aaaauaacga cagcucagau aaagcaacag uaauuccuaa cuuuaacacu acaaugcaag     3240

guagccuauu gggugacgau aguagagacu auuacagcuu ugaagucaaa gaagaaggag     3300

aaguuaauau agaacuagac aagaaagaug aguuuggagu aaccuggaca uugcacccug     3360

aauccaauau aaaugacaga auuacuuaug gccaagucga cggaaauaaa gucucaaaca     3420

aagugaaacu aagaccgggu aaauauuacc uuuuggugua caaauauagu ggcucaggaa     3480

acuaugaauu aagggucaac aaaugaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  6787
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt6)

<400>  6787
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuucuca aaauaauacu gaaccguggc aaaacaauga      120

aaagaaaaug ccuaaguaaa agacucaugc uggccaucac aauggcuaca auauucaccg      180

ucaacagcac cuuaccuauu uaugcagccg uagacaaaaa uaacgcuacu gccgccguac      240

aaaaugaaag caaaagauac acugucucgu aucuuaaaac acuaaauuac uacgaccuag      300

uagauuuauu aguaaaaaca gaaauagaaa accuaccuga ucucuuucaa uacucaucag      360

augccaaaga auuuuacgga aacaaaacac gaaugucuuu uauaauggau gaaauaggcc      420

gcagagcucc acaauacacc gaaaucgacc acaaaggaau accaacauua guggaagugg      480

uaagagcagg auuuuauuua ggcuuccaca acaaagaacu aaacgaaaua aauaaaagau      540

ccuucaagga aaggguaaua cccucaauau uagcaauaca gaaaaacccc aauuucaaac      600

uaggaacaga agugcaagac aaaaucguca gcgcaacggg acuucuagcc gguaacgaaa      660

cugcuccacc agaaguagua aacaacuuca ccccaauccu acaagacugu auuaaaaaca      720

uagacagaua ugcauuagac gaucuaaagu caaaggcuuu auuuaacguc uuagcugcac      780

cuacuuacga cauaacagaa uaccucaggg caacaaaaga aaaaccggaa aauacaccuu      840

gguacggaaa aauagauggc uucauaaacg aacuaaagaa auuagccuua uacggaaaaa      900

uuaacgauaa uaacucuugg auaauagaua augguauuua ccacauagcu ccguuaggga      960

aacugcauag uaacaauaaa aucggaauag aaacauuaac cgaagucaug aaaguauacc     1020

cauauuuauc aaugcaacac uuacaauccg ccgaccaaau caaaagacac uacgacagca     1080

aagaugcaga aggaaauaaa auaccauuag auaaauucaa gaaagaagga aaagaaaaau     1140

acugcccaaa aaccuauacu uucgacgaug gaaaaguaau aauaaaagcu ggagcaagag     1200

ucgaagaaga aaaaguaaaa cgacucuacu gggcaucaaa agaagucaac ucacaauucu     1260

ucagagucua uggcauagau aaaccgcuag aagagggaaa ccccgaugac auccuaacaa     1320

ugguaauaua caauucacca gaagaguaua aacuaaauag cguauuauac ggauacgaca     1380

caaauaacgg cggaauguac aucgaaccug aaggaaccuu cuucaccuau gagcgagaag     1440

cccaagaaag uacauacacc cuggaagaac uauucagaca ugaauacaca cauuaccuac     1500

aaggacgaua cgccgugcca ggacaauggg ggcgaacgaa auuauacgac aacgacagac     1560

ucacauggua ugaagaaggu ggagcagaau uauucgcagg caguacccgu acaucaggua     1620

uccuaccaag aaaaucuauc gucaguaaca uacacaacac aacuaggaau aaucgauaca     1680

aauuaucaga cacaguacau uccaaauacg gggccuccuu cgaauuuuac aacuacgcgu     1740

gcauguuuau ggauuauaug uauaacaaag auauggguau ucuaaacaaa uuaaacgacc     1800

uagccaagaa uaaugacgug gacggauacg acaacuauau uagggaccua ucaucaaauu     1860

augcauuaaa cgacaaauac caagaccaca ugcaagagag gauagauaau uacgaaaacc     1920

uaacaguacc auuugucgca gacgauuauu uagugcgaca ugcauacaaa aauccaaacg     1980

aaaucuacag ugagauuuca gagguagcaa aacucaagga ugcgaaaucc gaagucaaga     2040

aaagucaaua cuucaguaca uucacgcuaa gaggaucaua uacaggagga gccucaaaag     2100

gaaaauuaga agaccaaaaa gcaaugaaua aauucauaga cgauucauua aagaaacuag     2160

auaccuacag uuggaguggc uauaaaacac ucacugcaua uuucacaaau uacaaaguag     2220

acucaucuaa uaggguaacc uacgauguag uauuccacgg auaccuccca aaugaaggcg     2280

acagcaaaaa cucucuccca uacggaaaaa uaaacgggac auacaaaggu acugaaaaag     2340

agaaaaucaa auucagcagc gaaggauccu ucgacccaga cggaaaaauu guuaguuaug     2400

aaugggacuu cggagaugga aacaaaagua augaagaaaa cccagaacau uccuaugaca     2460

aagucgggac uuacaccgua aaauuaaaag uuacagauga uaaaggcgaa uccaguguau     2520

caacaacaac agccgaaauc aaagacuuaa gcgaaaauaa acuuccagua auauauaugc     2580

acguaccaaa aucuggagca cuuaaccaaa aaguaguauu cuacgguaaa gguacauacg     2640

auccagacgg aucaauagcu ggguaucaau gggacuuugg agacgguuca gauuucucau     2700

cagaacaaaa ucccucccac guauacacaa agaaagguga auacacagug acacuaagag     2760

ucauggauag cagcggccaa augucagaga aaacaaugaa aaucaaaaua acugaucccg     2820

uauauccaau aggcacagaa aaagaaccaa acaacagcaa agaaacagcc agcggaccaa     2880

uaguaccagg cauacccguc aguggaacua uagaaaauac auccgaccaa gacuacuuuu     2940

acuucgaugu aauaaccccu ggagaaguaa aaauagacau aaacaaauua gguuaugggg     3000

gcgcaacaug gguaguguac gaugaaaaua auaacgcagu aaguuaugcu acagacgacg     3060

gccaaaaucu auccggaaaa uucaaagcag acaaaccagg cagauacuau auucaucuau     3120

auauguuuaa cgguagcuac augccuuaca ggaucaacau agaaggaagc guagguagau     3180

agggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  6788
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt6)

<400>  6788
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacguaaau gccuuucaaa acgucuaaug uuggcaauua      120

cuauggcaac aauauuuaca guuaauucca cacuaccaau auaugcagcu guagacaaaa      180

acaaugccac agccgcagua caaaaugaau ccaaaaggua cacugucagu uaucuaaaaa      240

cucuuaacua uuacgaccua guugaccuau uaguaaaaac agaaauagaa aaccuaccag      300

acuuauucca auacucaucu gaugcuaaag aauuuuacgg aaauaaaacc cgcaugaguu      360

uuaucaugga ugaaauagga agacgagcgc cucaauauac ugaaaucgau cacaaaggaa      420

uaccgacgcu aguagaaguu guaagagccg guuuuuacuu aggcuuucac aacaaagaac      480

uaaacgaaau aaauaaacga ucauuuaaag agagaguaau acccagcauc cuugccauac      540

aaaagaaucc aaacuucaaa uuaggaacag agguacaaga caaaauagua uccgccacag      600

gccuauuagc aggaaaugag acagcacccc cugagguagu gaacaauuuc acaccaauau      660

uacaagauug cauuaaaaau auagauagau augcucuaga ugaucuaaaa ucaaaagcac      720

uauucaacgu acuagcagca cccacauacg auauaacaga auacuuacga gcgaccaaag      780

aaaaaccaga aaacacacca ugguacggaa aaauagacgg cuuuauaaau gaguuaaaga      840

aauuagcauu auaugguaaa auaaaugaua auaacagcug gauuauagac aacgggauau      900

aucauauagc accccuagga aaacuacacu caaacaauaa aauaggaaua gaaacauuaa      960

ccgaagucau gaaaguuuau ccuuacuuau ccaugcaaca cuuacaauca gcagaucaaa     1020

uaaaaagaca uuaugauuca aaagacgcag aagguaacaa aauaccccua gacaaauuua     1080

agaaagaagg aaaagaaaaa uauugcccaa aaacauacac auuugacgac gggaaaguaa     1140

ucauaaaagc aggagcgaga gucgaagaag aaaaaguaaa aagacucuac ugggcaucua     1200

aagaaguaaa cucccaauuc uucaggguau auggaauaga caaaccauua gaagaaggaa     1260

aucccgauga cauuuugaca augguaaucu auaauagucc ggaagaauau aaacugaaca     1320

gugucuuaua cggauaugau accaacaacg guggaaugua uauagaacca gagggaaccu     1380

ucuucaccua ugaaagggaa gcccaagaau caacauacac ucucgaggaa cuauuuaggc     1440

acgaauauac acacuauuua caaggacgau acgcaguacc aggacaaugg ggcaggacaa     1500

aacuuuacga uaacgacaga cuaacuuggu augaagaagg uggcgccgaa cuauucgccg     1560

guucaacucg cacaagcgga auauugccac gaaaaucaau cguaucuaac auacacaaca     1620

caacaagaaa uaaccguuac aaacuaucag auacaguuca cuccaaauac ggagcaaguu     1680

uugaauuuua caacuacgcc uguauguuua uggacuacau guauaauaaa gauaugggca     1740

uacuaaauaa acugaacgau uuagcuaaaa acaaugacgu agacggcuac gacaacuaca     1800

uaagagauuu aaguuccaac uaugcacuaa augauaaaua ucaagaucac augcaagaaa     1860

gaauagauaa cuaugaaaau uuaacaguac cuuuuguggc agacgauuac cuuguucgac     1920

acgcauauaa aaaccccaau gagauauauu cagaaauuuc agaaguagca aaauuaaaag     1980

augcaaaaag cgaaguaaag aaaagccaau acuucuccac auuuacccuc cgaggaucau     2040

acaccggcgg agccuccaaa ggaaaacuag aagaccaaaa agcuaugaac aaauucauag     2100

augacucccu aaagaaauua gacacauauu caugguccgg auacaaaacc cuaacggcuu     2160

acuucacaaa uuacaaaguc gacuccucaa auaggguuac auacgacguc guauuucacg     2220

gauaucuccc caaugaggga gacaguaaaa auucccuacc auacgggaaa auaaacggaa     2280

cauauaaagg gacagaaaaa gagaaaauaa aauucucguc ugaaggaucu uuugaccccg     2340

acgggaaaau ugugucauau gaaugggauu uuggagaugg aaauaaauca aaugaagaaa     2400

acccagaaca cagcuaugac aaaguaggca cauacaccgu aaaauuaaaa guaacagacg     2460

acaaaggaga aucaucagua uccaccacca cagcagaaau uaaagaucua ucugaaaaca     2520

aacucccagu aaucuauaug cacguaccua aaaguggcgc ucucaaucaa aaaguaguau     2580

uuuacggaaa aggaacauau gacccagacg gaagcauagc aggguaucaa ugggauuucg     2640

gagauggauc ugauuuuucu ucagaacaaa acccaucgca cguauacacc aagaaaggag     2700

aauauacagu aacacuaaga guuauggauu caucuggaca aaugucugag aaaacuauga     2760

aaauaaaaau aacagaccca guuuauccaa uaggcacaga aaaagaacca aacaacagua     2820

aagaaacagc aucaggacca aucgucccgg gcauaccagu aaguggaaca auagaaaaua     2880

caagcgacca agauuacuuc uacuucgaug uaauaacacc aggcgaaguu aaaauugaca     2940

uaaacaaacu cggauaugga ggagcaacau ggguaguaua ugaugaaaac aauaaugccg     3000

uaucuuacgc cacagacgau ggacaaaacc uaaguggaaa auuuaaagcu gauaaacccg     3060

gacgcuacua cauacaccug uauauguuua acgguucaua caugccauac aggauaaaca     3120

uagaagggag ugugggaaga uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  6789
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt6)

<400>  6789
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguua cuuuuauauc auuacuauuc cuauucucau      120

cagcauacag cguacagaac gaaucaaaaa gauacacagu aaguuacuua aaaacguuaa      180

acuacuacga ccuaguagau uuauuaguca aaaccgaaau ugaaaauuua cccgaccuuu      240

uccaauacuc uuccgaugca aaagaauuuu acggcaauaa aacacgaaug agcuucauaa      300

uggaugaaau cgguagacga gcuccccaau acacagaaau agaccacaaa ggaaucccua      360

cauuaguuga aguaguuaga gcaggauucu accuagguuu ucauaacaag gaauuaaaug      420

aaauaaauaa acgaucauuc aaagaacgag uaauaccauc aauacuugca auacagaaaa      480

acccaaacuu uaaacuugga acugaaguuc aagacaaaau agugucagca acaggacucc      540

uagcuggcaa ugaaacagcu ccaccagaag uaguaaacaa cuuuacacca auauuacaag      600

auugcauuaa aaauauagac cgcuacgcuu uagaugaucu aaaaaguaaa gcacuauuua      660

acguacuggc agcaccuacu uacgacauaa ccgaauaccu acgagcaaca aaagaaaaac      720

cugaaaacac ccccugguac ggaaaaauag acggauuuau caacgaacua aagaaauuag      780

cacuuuaugg aaaaauuaac gauaauaauu ccuggaucau cgacaauggc auauaccaua      840

uagcuccacu aggaaaauua cacucaaaca acaaaauagg aauagaaaca cuaacggagg      900

uaaugaaagu auacccauau cuaucaaugc aacaccuaca aucagccgau caaauaaaaa      960

gacauuauga cucaaaagau gcagaaggca acaaaauacc acuagacaaa uucaagaaag     1020

aaggaaaaga aaaauauugu ccgaaaacau acaccuuuga ugauggaaaa guaauuauaa     1080

aagcuggagc aagagucgaa gaagaaaaag uuaaacgauu auauugggca ucaaaagaag     1140

uaaauaguca auuuuuccgc gucuauggaa uagauaaacc ccuugaggaa ggaaauccag     1200

acgacauccu aacaauggua auauauaauu caccugaaga auacaaauua aauucaguac     1260

uauauggaua cgacacaaac aacggaggaa uguacauaga accagaaggu acauucuuua     1320

cauaugagag agaagcacaa gaaagcacau acacucuaga agaacuauuc agacacgagu     1380

acacccacua ccuacaaggu cgauaugcug uaccaggaca auggggaagg acaaaacuau     1440

acgauaauga cagacuaacc ugguacgaag aaggaggagc cgaacuauuc gcaggaagca     1500

cacguacauc agguauacua ccaagaaaau ccauagucag caacauacau aacacgacac     1560

guaacaacag auacaaauua agugacacag uucauagcaa auauggagcu ucauuugagu     1620

uuuauaacua cgcauguaug uucauggauu acauguacaa caaagacaug ggaaucuuaa     1680

auaaacuaaa cgauuuagcu aaaaauaaug auguagaugg auacgacaac uauauacgcg     1740

auuuaagcag uaacuacgca cuaaacgaua aauaccaaga ucacaugcaa gaaaggauag     1800

acaacuacga aaauuuaaca gucccauucg ucgcagacga uuaccuaguc agacacgccu     1860

auaaaaaucc uaacgaaaua uacucagaga uuagcgaggu cgcaaaauua aaagacgcaa     1920

aaagugaagu aaagaaaagu caauauuuca guacauuuac cuuaagaggc ucauauacag     1980

gcggagcaag uaaaggaaaa uuagaagauc aaaaagcaau gaauaaauuc auugaugaca     2040

gccuaaagaa auuagacaca uacucauggu cgggcuacaa aacccuuacc gcuuacuuua     2100

caaacuauaa agucgacagu ucaaacaggg ucacauacga cguuguauuc cacggcuacu     2160

uaccaaauga aggagacagu aaaaacuccc uaccauacgg aaaaauaaau ggaacguaua     2220

aaggaacaga aaaagagaaa auaaaauucu caucagaagg aucauucgac ccggacggaa     2280

aaauuguuuc cuacgaaugg gacuucgggg acgguaacaa aucgaacgaa gaaaauccug     2340

aacauucaua ugauaaagua ggaacauaca caguaaaacu aaaagucaca gaugacaaag     2400

gagaaucguc cguaucuacc acaacagcgg aaauaaaaga uuuaucagaa aauaaacuac     2460

ccguuauuua caugcauguc ccaaaaagcg gagcauuaaa ccaaaaagua guauuuuacg     2520

gaaaaggcac auaugaucca gacggaucaa uugccgguua ucaaugggac uucggagacg     2580

gaagcgacuu caguagugaa caaaaccccu cccauguaua cacaaagaaa ggugaauaca     2640

cagucaccuu aagaguaaug gacucaucag gacagaugag ugagaaaaca augaaaauaa     2700

aaauaaccga ccccgucuau ccaauaggaa ccgaaaaaga accaaauaau ucaaaagaaa     2760

cagcaucagg accaauagua cccggcaucc caguaucugg caccaucgaa aacaccucug     2820

aucaagacua cuucuacuuc gacguaauaa caccagguga aguaaaaauu gauaucaaua     2880

aacuaggaua cggcggagca acauggguag uuuacgacga aaacaacaac gcaguuagcu     2940

acgcuacaga ugacggacaa aaccuaagug ggaaauuuaa agcagacaaa ccuggaagau     3000

auuauaucca ucucuacaug uucaacgguu cuuauaugcc auauagaaua aacauagaag     3060

gcucaguagg aagauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6790
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt6)

<400>  6790
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguua cauucaucag cuuacuauuc cuauucagua      120

gcgccuacag caugaaaaga aaauguuuau ccaaaagacu aaugcuagcu aucacaaugg      180

cuacaauuuu cacagugaac ucuacauuac caauauacgc ugcaguugau aaaaacaacg      240

caacagccgc uagaagaaga agaaaacgag uacaaaacga aagcaaaaga uacaccgucu      300

cuuacuuaaa aacacuaaau uacuacgauc ugguagaccu ucuaguaaaa acugaaauag      360

aaaaucuacc agacuuauuc caauauucaa gcgacgcaaa agaauuuuac ggaaacaaga      420

caagaaugag uuuuauuaug gaugaaauug gacguagagc accccaauac accgaaauag      480

aucacaaagg cauacccacc uuaguggaag uuguaagagc cggguucuac uuaggauuuc      540

auaauaaaga auuaaaugaa auaaauaaac gauccuucaa agaaagaguc auaccaagca      600

uucucgcaau ucagaaaaac ccaaauuuca aacuaggaac cgaaguacaa gauaaaauug      660

uaucagcaac cggauuauua gcugguaacg aaacagcucc cccugaagua guaaauaacu      720

uuacccccau auuacaagau ugcauuaaaa auauagacag auacgccuua gacgaccuaa      780

aaucaaaagc acuauucaau guccucgcug cuccaacaua ugacauaaca gaauaccuua      840

gagcgacuaa ggaaaaaccc gaaaacaccc caugguaugg uaaaauagau gguuucauaa      900

acgaacuaaa gaaacucgca cuauacggaa aaauaaacga caacaauagc uggauaauag      960

acaauggaau auaucauaua gcaccauuag gaaaacuaca uucaaacaau aaaaucggaa     1020

uagaaacauu aacagaagua augaaaguau aucccuauuu aagcaugcaa caucuacagu     1080

cugcggacca aauaaaacgu cauuacgacu cuaaagacgc agaaggaaac aaaauuccac     1140

uagacaaauu uaagaaagaa gggaaagaaa aauacugccc aaaaaccuac acuuuugaug     1200

auggaaaagu aauuauaaaa gcuggagcac gcguagaaga agaaaaagua aaacgauuau     1260

acugggccag uaaagaagug aauagucaau ucuucagagu cuauggaauu gacaaaccuc     1320

uagaagaagg caacccagac gauauacuaa ccaugguuau auauaauucu ccagaagaau     1380

acaaacuaaa uucaguauua uacggauaug auaccaacaa cggagggaug uacauagaac     1440

cugaagguac uuucuuuaca uacgaaagag aagcacaaga aagcacauau accuuagagg     1500

aacuauuuag acacgaauau acacacuacc ugcaaggaag auaugcugug ccaggacaau     1560

ggggacguac uaaacuauac gacaacgaua gacuaacaug guaugaagaa ggaggagcag     1620

aacucuuugc uggcuccacc agaacaagug gaaucuuacc aagaaaaagu auaguaucaa     1680

acauacauaa cacaacaaga aauaacagau acaaacucag cgacacagua cacucaaaau     1740

acggagcuag cuucgaauuu uauaauuacg caugcauguu cauggacuac auguacaaca     1800

aagauauggg aaucuuaaac aaacuaaaug aucuagcgaa aaauaaugau guugaugguu     1860

acgacaacua uauccgugau cucucaucaa acuacgcacu gaacgacaaa uaccaagauc     1920

auaugcaaga acguauagau aauuaugaaa auuuaacugu acccuucgua gcagaugauu     1980

acuugguuag gcaugcauac aaaaauccua augaaauaua cucagaaaua ucugaaguag     2040

ccaaacuaaa agaugcaaaa agugaaguua agaaaagcca auauuuuucc acauuuacau     2100

uacgaggauc cuauacugga ggggccagua aagguaaacu agaagaccaa aaagcaauga     2160

acaaauucau cgaugauucc cuaaagaaau uagauacaua uaguugguca ggcuacaaaa     2220

cacuaacagc cuauuuuaca aauuacaaag uagauucaag caauagaguu acauacgacg     2280

uaguauucca ugguuauuua ccaaaugaag gcgacaguaa aaauucauua ccauacggaa     2340

aaauaaaugg aacauauaaa ggaacggaaa aagagaaaau aaaauucucc ucugaaggau     2400

ccuuugaccc agacggaaaa aucguuagcu acgaauggga cuucggugau gguaacaaau     2460

caaacgaaga aaacccugaa cacagcuacg acaaaguagg aaccuacaca gucaaacuca     2520

aaguaacaga ugauaaaggu gaaucuucug uuucuacgac aacagcagaa aucaaagauu     2580

uauccgaaaa caaacuccca gucauauaua ugcacguacc aaaaucaggu gcacuuaauc     2640

aaaagguugu auuuuaugga aaagguacau augaucccga cggaucaauc gcaggauacc     2700

aaugggacuu cggagacggg ucagauuucu ccucugaaca aaacccaagc cacguauaca     2760

ccaagaaagg agaauauacc guaaccuuac gagucaugga uaguucaggu caaaugucag     2820

agaaaacaau gaaaaucaaa auaacugauc caguauaccc aaucggaaca gaaaaagaac     2880

caaauaauag caaagaaaca gcaaguggac ccaucgugcc aggcauccca guaucgggca     2940

caauagaaaa uacgagcgac caagacuauu ucuacuuuga cgucauaaca ccaggagaag     3000

uaaaaaucga uauaaauaaa cuaggauacg gaggagccac augggucguc uacgaugaaa     3060

acaacaaugc cgugagcuau gcaacagacg auggacagaa ucuuucuggg aaauucaaag     3120

cagauaaacc aggacgauac uauauacacu uauacauguu uaaugguagu uacaugccau     3180

accgaauaaa cauugaagga agcguuggaa gaugaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  6791
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt6)

<400>  6791
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gguaccugga uauuauucgc augccuacua ggcgcagcau      120

ucgccaugcc auuaccacca cacccaggac acccaggaua caucaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc auacccauca uacggauacg      240

aaccaauggg uggauggcua caccaccaaa uaauaccagu acuaucacaa caacacccac      300

caacacacac acuacaacca caccaucaca uaccaguagu accagcacaa caaccaguaa      360

uaccacaaca accaaugaug ccaguaccag gacaacacuc caugacacca auacaacauc      420

accaaccaaa ccuaccaccc ccagcacaac aaccauacca accacaacca guacaaccac      480

aaccacacca accaaugcaa ccacaaccac caguacaccc caugcaacca cucccaccac      540

aaccaccacu accaccaaug uucccaaugc aacccuuacc accaaugcua ccagaccuaa      600

cacuagaagc auggcccuca acagacaaaa caaaaagaga agaagucgac uaaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  6792
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt6)

<400>  6792
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca ccauacccau      180

cauacggaua cgaaccaaug ggaggauggu aaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  6793
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt6)

<400>  6793
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca ccaccaaugc      180

uaccagaccu aacacuagaa gcauggccau caacagacaa aacaaaaaga gaagaaguag      240

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  6794
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt6)

<400>  6794
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa ucaauaagac      240

caccauaccc aucauacgga uacgaaccaa ugggaggaug guaaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  6795
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt6)

<400>  6795
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa ucaauaagac      240

caccaccaau gcuaccagac cuaacacuag aagcauggcc aucaacagac aaaacaaaaa      300

gagaagaagu agacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  6796
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt6)

<400>  6796
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augcuuagua ggagcagcau      120

ucgccaugcc acuaccacca caccccggcc acccaggaua cauaaacuuc ucauacgaag      180

uauuaacacc acuaaaaugg uaccaaucaa ugauacgccc accauacucc ucauacggau      240

acgaaccaau gggcggcugg uuacaccauc aaauaauacc aguaguaucc caacaacacc      300

cacuaacaca cacacuacaa ucacaccacc acauaccagu aguaccagca caacaaccac      360

gaguacgcca acaagcacua augccaguac caggacaaca aucaaugaca ccaacacaac      420

accaccaacc aaaccuacca uuaccagcac aacaaccauu ccaaccacaa ccaguacaac      480

cccaaccaca ccaaccaaug caaccacaac caccaguaca accaaugcaa ccacuccuac      540

cccaaccacc acuaccacca auguucccac uaagaccacu accaccaaua cuaccagacc      600

uacaccuaga agcauggcca gcaacagaca aaacaaaaca agaagaagua gacuaaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  6797
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt6)

<400>  6797
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aaugauaaga ccaccauacu      180

caucauacgg auacgaacca augggaggau gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6798
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt6)

<400>  6798
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguauuaaca ccacuaaaau gguaccaauc aaugauaaga ccaccaccaa      180

uacuaccaga ccuacaccua gaagcauggc cagcaacaga caaaacaaaa caagaagaag      240

uagacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6799
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt6)

<400>  6799
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaucca ggacacccag      180

gauauauaaa uuucucauac gaaguauuaa caccacuaaa augguaucaa ucaaugauaa      240

gaccaccaua cagcucauac ggauacgaac caaugggagg augguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6800
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt6)

<400>  6800
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaucaa ucaaugauaa      240

gaccaccacc aauacuacca gaccuacacc uagaagcaug gccagcaaca gacaaaacaa      300

aacaagaaga aguagacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6801
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt6)

<400>  6801
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaccugga uauuauucgc augccuacua ggagccgcau      120

ucuccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uauuaacccc auuaaaaugg uaucaaaaca ugauaagaca cccauacaca ucauacggau      240

acgaaccaau gggaggaugg cuacaccacc aaauaauacc aguaguaucc caacaaacac      300

cacaaucaca cgcacuacaa ccacaccacc auauaccaau gguaccagca caacaaccag      360

gaauaccaca acaaccaaug augccacuac caggacaaca cucaaugaca ccaacacaac      420

accaccaacc aaaccuacca cuaccagccc aacaaccauu ccaaccacaa ccaguacaac      480

cacaaccaca ccaaccacua caaccccaau ccccaaugca cccaauacaa ccacuacuac      540

cacaaccacc acuaccccca auguucucaa ugcaaucacu acuaccagac cuaccacuag      600

aagcauggcc agccacagac aaaacaaaaa gagaagaagu agacuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6802
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt6)

<400>  6802
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa uaugauaaga cacccauaca      180

caucauacgg auacgaacca augggaggau gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6803
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt6)

<400>  6803
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa caugauaaga cacccaucac      180

uacuaccaga ccuaccacua gaagcauggc cagcaacaga caaaacaaaa agagaagaag      240

uagacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6804
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt6)

<400>  6804
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaucca ggacacccag      180

gauauauaaa uuucucauac gaaguauuaa caccacuaaa augguaucaa aauaugauaa      240

gacauccaua uacaucauac ggauacgaac caaugggagg augguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6805
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt6)

<400>  6805
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa aacaugauaa      240

gacacccauc acuacuacca gaccuaccac uagaagcaug gccagcaaca gacaaaacaa      300

aaagagaaga aguagacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6806
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt6)

<400>  6806
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacuc ggugcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacauac      180

gacacccaua cacaucauac ggauacgaac caaugggagg auggcuacac caccaaauaa      240

uacccguagu aucucaacaa acaccacaau cacacgcacu acaaccacac caccacauac      300

caaugguacc agcacaacaa ccaggaauac cacaacaacc aaugaugcca uuaccaggac      360

aacacucaau gacaccaaca caacaccacc aaccaaaccu accacuacca gcacaacaac      420

cuuuccaacc acaaccagua caaccacaac cacaccaacc acuacaacca caaucaccaa      480

ugcacccaau acaaccauua cuaccacaac caccacuacc accaauguuc ucaaugcaau      540

cacuacuacc agaccuacca cuagaagcau ggccagcaac agacaaaacc aaaagagaag      600

aaguagacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  6807
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt6)

<400>  6807
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uauucuucgc cugccuacua ggcgcaucac      120

uagcaaugcc acuaccacca cacccaggac acccaggaua uauaaacuuc ucauacgaag      180

uacuaacacc ucuaaaaugg uaccaaaaca ugauaagaca uccauacaca ucauacggau      240

acgaaccaau gggcggaugg uuacaccacc aaauaauacc aguagucucc caacaaacac      300

cacaaucaca cgcauuacaa ccccaccacc acauacccau gguaccagcc caacaaccag      360

gaauaccaca acaaccaaug augccacuac caggacaaca cucaaugaca ccaacacaac      420

accaccaacc aaaccuccca uuaccagcac aacaacccuu ccaaccacaa cccguacaac      480

cacaaccaca ccaaccacua caaccacaau caccaaugca cccaauacaa ccacuacuac      540

cccaaccacc acuaccacca auguucucaa ugcaaucacu acuacccgac cuaccauuag      600

aagcauggcc agcaacagac aaaacaaaaa gagaagaagu agacuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6808
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt6)

<400>  6808
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaucaaaaca ugauaagaca cccaucacua uuaccagacc      240

uaccacuaga agcauggcca gcaacagaca aaacaaaaag agaagaagua gauuaaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  6809
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt6)

<400>  6809
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggagccgcau      120

ucucaaugcc ccuaccacca cacccaggac acccaggcua cauaaacuuc ucauacgaag      180

accuauaccu agaagcaaua agaauagaca gaacagcauu cguccuaaca ccauuaaaau      240

gguaccaaaa caugauaaga cacccauaca caucauacgg auacgaacca augggaggcu      300

ggcuacacca ccaaauaaua cccguaguau cccaacaaac accacaauca cacgcacucc      360

aaccacacca ucacauaccu augguaccag cacaacaacc cggaauacca caacaaccaa      420

ugaugccacu accaggacaa cacucaauga caccuacaca acaccaccaa ccaaaccuac      480

cauuaccagc acaacaacca uuccaaccac aaccaguaca accacaacca caccaacccc      540

uacaaccaca aucaccaaug cacccaauac aaccacuacu cccacaacca ccccuaccac      600

ccauguucuc aaugcaaucu uuacuaccag auuuaccauu agaagcaugg ccagcaacag      660

acaaaacaaa aagagaagaa guagauuaag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  6810
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt6)

<400>  6810
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcacaugga uacuauucgc augccuacua ggagcagcau      120

ucuccaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacucacccc acuaaaaugg uaccaaaaca ugauaagaca cccaacacca caaucccacg      240

cacuccaacc acaccaccac auaccaaugg uaccagcaca acaaccagga auaccacaac      300

aaccaaugau gccacuacca ggacaacacu caaugacacc aacacaacac caccaaccca      360

accuaccacu accagcacaa caaccauuuc aaccacaacc aguacaacca caaccacacc      420

aaccacuaca accacaauca ccaaugcacc caauacaacc acuacuccca caaccaccac      480

uacccccaau guucucaaug caaucacuau uaccagaccu accacuagaa gcauggccag      540

caacagacaa aacaaaacga gaagaaguag acuaaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  6811
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt6)

<400>  6811
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

uuucauacga aguacuaacc ccacuaaaau gguaccaaaa caugauaaga caccccuaca      180

caucauacgg cuacgaacca augggaggau ggcuacacca ccaaauaaua ccaguaguau      240

cacaacaaac accacaauca cacgcacucc aaccacacca ccacauacca augguaccag      300

cacaacaacc cggaauacca caacaaccaa ugaugccacu cccaggacaa cacucaauga      360

caccaacaca acaccaccaa ccaaaccuac cacuaccagc ccaacaacca uuccaaccac      420

aaccaguaca accacaacca caccaaccac uacaaccaca aucaccaaug cacccaauac      480

aaccacuacu accacaaccc ccacuacccc caauguucuc aaugcaauca cuacuaccag      540

accuaccacu agaagcaugg ccagcaaccg acaaaacaaa aagagaagaa gucgacuaag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  6812
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt6)

<400>  6812
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagggguag cuagacuacc ucuacucuua ggacuccuau      120

uguuaccacg gccaggaaga ccguuagauc uagcggacua cacauaugau cucgcagaag      180

aagacgacag ugaaccgcua aauuacaaag auccauguaa agcggccgca uuuuugggag      240

auauagcauu agaugaagaa gacuuaagag cauuucaagu acaacaagcu guugaucuaa      300

gaagacacac ggcccgaaaa agcaguauaa aagcagcggu accaggcaac acaagcacgc      360

caucaugcca aaguacaaac ggacaaccac aaagaggggc uugcgggaga uggagaggaa      420

gaagcagaag cagacgcgca gcuacuucaa gaccugaaag aguuuggccu gacggcguaa      480

uaccauucgu aauaggaggc aauuuuacag gaagucagcg cgcaguuuuu cggcaagcaa      540

ugcgccacug ggaaaaacau acuuguguaa cauucuuaga gcgaacagau gaagauuccu      600

auauaguuuu cacauacagg cccugcggau guuguucaua uguaggaaga cgcgggggag      660

gaccacaagc gauaaguaua ggaaaaaauu gugacaaauu cggaauaguu guccaugaau      720

uaggucacgu ugugggauuc uggcacgaac acacacgacc agauagagac agacauguaa      780

guauaguaag ggaaaauaua caaccagggc aggaauacaa cuuuuuaaaa auggaacccc      840

aagagguaga aucacuuggc gaaacuuacg auuucgauag uauaaugcau uaugcuagaa      900

auacauuuuc gagaggaaua uuccuagaca cuauaguacc gaaauacgaa guaaauggag      960

ugaaaccccc aauaggccaa agaacuagac uaucaaaagg agacauagca caggcaagaa     1020

aauuauauaa augucccgcg uguggugaaa cauuacaaga uucuacagga aauuuuucau     1080

cuccugaaua uccuaauggc uauagugcac acaugcauug uguauggcgc auuucaguaa     1140

caccaggaga aaaaauuauu uugaauuuca caagucuaga cuuauacaga aguagauuau     1200

guugguauga cuauguagaa gucagggaug gauucuggag aaaagcuccu cuaaggggaa     1260

gauuuugugg aagcaaauua ccugaaccaa uaguuagcac agauucaaga cuuuggguag     1320

aauuuagaag uaguucaaau uggguaggaa aaggauuuuu cgcaguguau gaagcaauuu     1380

gcgguggaga uguaaaaaaa gacuaugggc acauacaaag cccaaacuau ccugaugauu     1440

auagaccauc aaaaguaugu auauggcgaa uacaaguuag ugaaggguuu cacguaggau     1500

uaacuuuuca auccuucgaa auagaaagac augacucuug cgcauaugau uauuuagaag     1560

uuagagacgg acauagugag aguaguacuc uaaucggaag auacugcggc uaugaaaaac     1620

cugaugacau uaaaagcacu agcucuagau uauggcuaaa auuuguaagu gaugguagca     1680

uaaauaaggc agguuuugca guaaacuuuu uuaaagaggu ugaugaaugu ucgaggccua     1740

auagaggugg uugugaacaa cggugcuuga auacacuagg aagcuacaaa ugcucaugcg     1800

auccaggcua cgaauuagcg ccagauaaaa gaagauguga agcagcaugu ggaggauuuu     1860

ugacuaaacu aaauggauca auaacaaguc cagguuggcc gaaagaauac ccuccuaaua     1920

aaaacuguau uuggcaacuu guagcaccua cucaauauag aauaucauug caauucgauu     1980

uuuucgagac agaaggaaac gacguaugua aauaugacuu uguggaagua agaagugguc     2040

uaaccgcuga uaguaagcua cacggaaaau ucugcgguag ugagaaacca gaaguaauaa     2100

cgucacaaua caauaauaug agaguugaau uuaagaguga caauacaguu ucaaaaaaag     2160

gauuuaaagc acauuuuuuc ucagacaaag augaguguag uaaagauaau ggaggaugcc     2220

agcaagacug cguaaauaca uucggaagcu augaauguca augucgaucc ggcuuuguau     2280

uacacgauaa uaaacacgau uguaaagaag cuggaugcga ucacaaagua acgaguacua     2340

gcggaacaau uacaagccca aauuggccgg acaaauaucc cucaaaaaaa gaauguacuu     2400

gggcaauauc uucuacaccg ggucauagag ugaaauuaac auucauggaa auggacauag     2460

aaucacaacc agaaugugca uaugaucacc uugaaguauu cgaugguaga gaugcuaaag     2520

cuccaguacu gggucgcuuu uguggaagua aaaaacccga gccuguauua gcaacaggau     2580

caagaauguu ccuuagauuc uacuccgaca auucaguaca gagaaaaggu uuccaagcuu     2640

cucacgcaac agaaugugga ggccaagugc gagcggaugu aaaaacaaaa gacuuauauu     2700

cucacgcaca guuuggagac aauaauuauc caggaggugu ggauugugaa uggguuauag     2760

ucgcagaaga aggauacgga guagagcuag ucuuucaaac auuugaggua gaagaagaaa     2820

cugauugugg auacgacuau auggaacucu uugauggaua cgacucaaca gcaccccgau     2880

uagguagaua uuguggaucu ggaccacccg aagaaguaua uuccgcagga gacagcguau     2940

uagucaaguu ccacuccgau gauaccauca cuaaaaaagg auuucaucuu agauauacaa     3000

gcacaaaauu ucaagacacu cuucacagcc gaaaauaggg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  6813
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt6)

<400>  6813
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guagcuggua cuagaugccu acuagcauua cucuuaccac      120

aaguauuacu aggaggagca gcaggauuag ucccagaacu agguagaaga aaauucgcag      180

cugccucauc aggaagaccc agcucacaac cuucagacga aguccuauca gaauuugaau      240

ugagauuacu aucaauguuc ggacuuaaac aaagaccaac accaucaaga gaugcaguag      300

uaccaccaua uaugcuagau uuauauagaa gacacucagg acaaccagga aguccagcuc      360

cagaccauag auuagaaaga gcagcaagua gagcaaacac agucaggagc uuucaucacg      420

aagaaucacu agaagaauua ccagaaacau caggaaaaac cacaagaaga uuuuucuuua      480

accuuaguuc aauaccaaca gaagaauuca ucacaagugc agaacuacaa gucuucaggg      540

aacaaaugca ggacgcacua ggaaauaauu caucauucca ucauagaaua aauaucuaug      600

aaauaauaaa accagcaaca gccaacucaa aauucccagu aacaagacua cuagacacaa      660

gacuaguaaa ccaaaacgca agcagauggg aaagcuuuga uguaacacca gcaguaaugc      720

gauggacagc acaaggucac gcaaaucacg gauucguagu cgaagucgcg caucuagaag      780

aaaaacaagg uguaagcaaa cgacauguaa gaauaaguag aaguuuacac caagaugaac      840

auucaugguc acaaauaaga ccacuccuag uaacauucgg acaugacggu aaaggacacc      900

cacuacacaa acgagaaaaa agacaagcaa aacauaaaca aagaaaaaga cuaaaaucau      960

caugcaaaag acauccguua uauguugacu uuucagaugu aggauggaac gacuggaucg     1020

uagcaccccc aggauaucac gcauucuauu gucauggaga auguccauuu ccauuagcag     1080

aucacuuaaa uagcacaaac cacgccauug uacaaacucu agucaauuca gucaauucaa     1140

aaaucccaaa agcaugcugc guaccuacag aacuaucagc aauuucaaug cuauaccuag     1200

acgaaaauga aaaaguagua cuuaaaaacu aucaagacau gguuguagaa ggauguggau     1260

gcagauaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  6814
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt6)

<400>  6814
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auacccggaa acagaaugcu aaugguagua uuacuaugcc      120

aaguauuacu aggaggagcu agccaugcca gcuuaauucc ugaaacaggc aaaaagaaag      180

uagcagaaau acaaggacac gcaggaggaa gaagaucagg acaaagccau gaacuacuaa      240

gagacuucga agcaacauua cuacaaaugu uuggacuacg acgaagacca caaccuagua      300

aaagcgcagu cauaccagac uauaugagag aucuauaucg cuuacaaagc ggagaagaag      360

aagaagaaca aauacauuca acaggauuag aauacccaga aagacccgca ucaagagcaa      420

auacagugag gucauuccau caugaagaac aucuagaaaa uauaccagga acaucagaaa      480

auucagcauu cagauuuuua uucaauuuaa guucuauacc agaaaacgaa guaauaucau      540

cugcagaacu aagauuauuc agagaacaag uugaucaagg accagacugg gaaagagguu      600

uucacagaau aaauaucuau gaaguaauga aaccuccagc agaaguaguu ccagggcauc      660

uaaucacaag auuacucgau acaagauuag uacaccauaa cguaacacga ugggaaacau      720

uugauguauc accagcaguu cuaagaugga caagagaaaa acaaccgaau uacggauuag      780

caauagaagu uacucacuua caucaaacaa gaacccacca aggacaacau guaagaauau      840

cccgaucauu accacaaggc ucaggaaauu gggcacaacu aagaccacuc cucguaacau      900

uuggacauga cggaagagga caugcucuca ccagaagaag acgagcaaaa agaucaccaa      960

aacaccauag ccaaagagcu agaaagaaaa auaaaaauug cagaagacau aguuuauacg     1020

uugacuucuc agauguagga uggaaugauu ggauaguagc accaccuggu uaccaagcau     1080

uuuauuguca cggagacugu ccauuuccuu uagcagauca cuuaaacagu acaaaucacg     1140

caauaguaca aacucuaguu aacucaguaa acagcucuau accaaaagca ugcugugucc     1200

caacagaacu aucggcaauu ucaauguuau auuuagauga auaugauaaa guaguacuua     1260

aaaauuauca agaaauggua guagaaggau gcggauguag auaaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  6815
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt6)

<400>  6815
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaggauuag gucguagagc acaaugguua ugcugguggu      120

gggguuuacu auguucaugu uguggcccac caccccuaag accaccauua cccgcagcag      180

cggcugcagc cgcaggagga caacuauuag gagauggagg aaguccaggc agaacagaac      240

aaccaccgcc aagcccccaa agcucaucug gauuucuaua cagaagauua aaaacacaag      300

aaaagagaga aaugcaaaaa gaaauacuau cgguauuagg acugccacau cgacccagac      360

cacuacacgg auuacaacaa ccccaaccac ccgcacuucg acaacaagaa gaacaacaac      420

aacaacaaca acuaccaaga ggcgaaccuc caccaggaag auuaaaauca gcaccacuau      480

uuauguuaga uuuauauaac gcauuaucag cagacaauga cgaagacgga gcaucagaag      540

gagaaagaca acaaucaugg ccccaugaag cagcaucaag uucacaacga agacaaccac      600

cuccaggagc ugcucaucca uuaaacagaa aaucacuucu cgccccagga aguggcucug      660

gaggugcaag uccauuaaca ucagcacaag auagcgcuuu cuuaaaugau gcagauaugg      720

uaaugucauu uguaaaucua gucgaauacg auaaagaauu uucaccaaga caacgacauc      780

auaaagaauu uaaauucaau uuaagucaaa uaccugaagg ugaaguaguu acagcugcug      840

aauuucgaau auauaaagac uguguaaugg gaucauuuaa aaaccaaaca uucuuaauau      900

caauauauca aguuuuacaa gaacaucaac auagagauag ugaucucuuu uuacuagaua      960

caagaguagu augggcuagu gaagaagguu gguuagaauu ugacauaaca gcuacgagua     1020

auuuaugggu uguaacacca caacauaaua ugggucuaca acuuagcgua guuacacgag     1080

augguguaca uguacaccca agagcagcag gucuaguagg aagggaugga ccuuaugaca     1140

agcaaccauu caugguagca uucuuuaaag uaagcgaagu ucauguaaga acuacaagau     1200

cagcuucauc aagaagaaga caacaaaguc gaaacagaag uacacaaagu caagauguug     1260

caagaguauc cagugcaucu gauuauaaca guagcgaacu aaaaaccgca uguagaaaac     1320

acgaauuaua cgucagcuuu caagaucuag gauggcaaga uuggauaauc gcaccaaaag     1380

gauaugcagc caauuauugu gauggagaau gcaguuuucc uuuaaaugca cacaugaaug     1440

caacaaauca cgcuauaguu caaacacuug uucacuuaau gaauccugaa uacguaccaa     1500

aaccauguug cgcaccuaca aaauuaaacg caauaucagu acuauacuuu gaugauaauu     1560

caaacguaau acuuaaaaag uauagaaaua ugguaguaag agcauguggu ugucacuaag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  6816
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt6)

<400>  6816
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauguaagau cacuccgagc agcagcacca cacucauuug      120

uagcauuaug ggcaccacua uucuuauuaa gauccgcacu cgcagacuuc aguuuagaca      180

augaaguaca cucaucauuu auacaucgaa gauuacgauc ccaagaaagg agagaaaugc      240

aaagagaaau acucucaaua cuagguuuac cccacagacc aagaccacac cuacaaggaa      300

aacauaauuc cgcaccaaug uucaugcuag aucuauacaa cgcaauggca guagaagaag      360

gaggaggacc aggaggccaa gguuucucau acccauauaa agcaguauuc aguacacaag      420

gaccuccacu agcaucccua caagauucuc acuucuuaac ugaugcagau auggucaugu      480

cauucguuaa cuuaguagaa caugauaaag aauuuuuuca cccaagauau caccaucgug      540

aauuuagauu cgaccuauca aaaauuccag aaggagaagc cguaacagca gcagaauuca      600

ggauuuauaa agacuauauc cgagaacgau ucgacaacga aacauucaga auaucaguau      660

aucaagucuu acaagaacau cucggccgag aaucagacuu auucuuauua gauucgagaa      720

cucuaugggc aucugaagaa ggaugguuag uauuugauau aacagcaaca agcaaucauu      780

ggguaguaaa cccccgacau aaucuaggau uacaauuauc aguagaaaca cuugauggcc      840

aaagcauuaa cccaaaauua gcaggacuaa uaggcagaca ugguccacaa aacaaacaac      900

cauucauggu agcauuuuuc aaagcaacag aaguccauuu cagaaguaua agaucaacag      960

gaaguaaaca aagaucacaa aacagaucaa aaacaccaaa aaaucaagaa gcacuaagaa     1020

uggcuaacgu agcagaaaau agcucuagug accaaaggca agccuguaaa aaacacgaau     1080

uauauguauc auucagagau uuaggauggc aagauuggau cauagcacca gaaggauaug     1140

cagcauauua cugugaagga gaaugugcuu ucccauuaaa cucauacaug aacgcaacaa     1200

aucacgcaau cguacaaaca cucguacacu uuauuaaucc agaaacagua ccaaaacccu     1260

gcugcgcacc cacacaauua aacgcaauau caguacuaua cuuugacgau ucaucaaacg     1320

uaauauuaaa aaaauacaga aacauggucg uaagagcaug ugguugccau uaaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  6817
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt6)

<400>  6817
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagcaucag cagcacuacu augccuacua cuaacagcag      120

cagcauucuc accacaagga cuagcacaac caguaggaau aaacacauca acaacaugcu      180

gcuacagauu cauaaacaaa aaaauaccaa aacaaagacu agaaucauac agaagaacaa      240

caucaucaca cugcccaaga gaagcaguaa uauucaaaac aaaacuagac aaagaaauau      300

gcgcagaccc aacacaaaaa uggguacaag acuucaugaa acaccuagac aaaaaaacac      360

aaacaccaaa acuauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  6818
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt6)

<400>  6818
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuacuaacuu ugauaauauu auuaccaguu guuucaaaau      120

uuucuuuugu gucauuaucu gcaccgcaac acuggaguug uccagaagga acucuagcug      180

gaaauggaaa uucuacaugu guugggccug caccauuucu aauauucagc cauggaaacu      240

caauuuucag aauagauacu gagggaacca acuaugagca acucguuguc gacgcuggag      300

uaucuguaau aauggauuuu cauuacaaug agaaacgcau auacuggguu gacuuagaac      360

gacaauuauu acaaagagua uuucuaaaug gaagcagaca agaaagggua ugcaauauag      420

agaaaaaugu gaguggaaug gcaaucaauu ggauaaauga agaagugaua uggucaaacc      480

aacaagaagg aauuauaaca guaacagaua ugaaaggcaa uaauagccau auacuguuga      540

gcgcccuuaa auauccagcu aacguagcag uagauccagu agaaagauuu auauuuugga      600

guucugaagu cgcaggauca cuauaccgag cugaccuuga uggaguaggu guaaaggcuu      660

uacuagaaac aucagagaaa aucacagcag uaagucuuga cguacuagau aaaagauuau      720

ucuggaucca auauaaccgc gaagggucua auucccuuau auguucaugu gacuacgacg      780

gaggcucagu acauauauca aaacauccga cccaacauaa ucuauuugcu augagccuuu      840

ucggggacag aaucuuuuau ucgacaugga aaaugaaaac aauuuggaua gcaaauaaac      900

acacaggaaa agacauggua agaauuaauu uacauagcuc uuucguaccu uugggagaau      960

uaaaaguagu acauccguug gcacagccua aagcagaaga cgauacaugg gaaccugaac     1020

aaaaauugug caaauugcga aaaggaaacu guucaucgac cguuugugga caagacuuac     1080

aaagucacuu gugcaugugu gcggaaggau augcucuauc cagagauaga aaauauugug     1140

aagaugucaa cgaaugugcu uuuuggaauc auggaugcac acuaggaugc aaaaacacac     1200

cagguucuua uuacuguacc uguccaguag guuuuguuuu acuaccagac gguaaaagau     1260

gucaccagcu aguaucgugu ccacgcaacg uaucugaaug uucucacgau uguguacuua     1320

ccagcgaagg accauuaugu uuuuguccgg agggaagugu acuagaacgu gacgguaaaa     1380

cauguucagg augcucauca ccugauaacg gugguuguag ucaauuaugc gucccacuua     1440

guccuguaag uugggaaugu gacugcuucc caggauauga uuugcaauua gaugagaaaa     1500

gcugugcagc cagcggaccu caacccuuuc uccuuuucgc aaacagccaa gauauaagac     1560

auaugcauuu ugauggaacu gauuauggaa cgcuauuaag ucaacaaaug ggaaugguuu     1620

acgcacuaga ucaugauccu guagaaaaua aaauauauuu ugcucacaca gccuuaaaau     1680

ggauagaacg ggcaaauaug gacgguagcc aaagagaacg acuaaucgaa gaaggaguag     1740

auguuccuga aggauuagca guagauugga ucggaagacg auuuuauugg acggauaggg     1800

gaaaaagccu aauugguaga uccgaccuua auggaaaaag aucaaaaaua auaacaaaag     1860

aaaacauaag ccaaccacgc ggaauugcgg uacauccaau ggcaaaacgg cuauuuugga     1920

cagauacagg aauaaaccca agaauagaaa guucuucuuu acagggacua ggacgucuag     1980

uaauagcaag cuccgauuua auuuggccca gugguauaac gauagacuuu uuaacugaua     2040

aacuauacug gugugaugca aagcaaucag ucauugaaau ggcaaaucua gauggaucua     2100

aaagaagaag acuaacucaa aacgauguag gacacccauu ugccguagca guauuugaag     2160

auuauguuug guucucagau ugggcaaugc caagcguaau gagaguaaau aaaagaacag     2220

gaaaagauag agucagauug caaggaagca uguuaaaacc guccagucuu gucgucguuc     2280

auccccuugc aaaaccaggu gcggauccau gucuauauca aaacggagga ugugaacaua     2340

uuugcaagaa acgguuaggu acugcauggu gcagcugucg agaaggauuc augaaagcga     2400

gcgaugguaa aacauguuua gcacucgaug gacaucaacu acuagcuggc ggagaaguag     2460

accugaaaaa ccaagugaca ccccuugaua uacuuaguaa aaccagagua agugaagaua     2520

auauaacgga aucacaacau auguuaguag cagaaaucau ggugagcgau caagaugauu     2580

gugcacccgu aggauguagu auguaugcaa gaugcaucuc agaaggagaa gacgcaaccu     2640

gccagugcuu aaaaggcuuu gccggcgacg gcaaacugug cucagauauu gaugagugcg     2700

aaaugggugu gcccguuugu ccuccagcgu cauccaaaug uauaaauaca gaaggagguu     2760

auguauguag augcagcgag gguuaucaag gugauggcau acacuguuug gauaucgaug     2820

aaugucaauu aggagaacau ucuugugggg aaaaugcaag uuguacaaau acagaaggag     2880

guuauacuug uaugugugcu ggccguuuaa gugaaccugg cuuaauaugu ccagacagca     2940

cuccgccucc ucaccuaaga gaggaugauc accauuacag cguacgcaau agcgauucag     3000

aaugcccucu aagucacgac ggguacuguc uacaugacgg aguauguaug uacauagagg     3060

cuuuagauaa guaugcaugu aacugugucg uugguuacau aggagaaaga ugucaauauc     3120

gagauuuaaa auggugggaa uuaagacacg cgggacaugg ccaacaacaa aaaguaauag     3180

ucguagccgu cugcguaguu guucuaguaa uguuacuacu acugagucuu uggggugcac     3240

acuauuauag aacacaaaaa cuacuaucga aaaaucccaa aaauccauau gaagaaagca     3300

guagagaugu aaggucaaga cgaccggcug acacagaaga ugggauguca aguugcccac     3360

aaccaugguu uguaguaaua aaagagcauc aagaccuuaa aaacggaggu cagccaguag     3420

cuggagaaga cggucaggcu gcggauggga guaugcaacc aacaucuugg agacaagaac     3480

cucaacugug cggaaugggu acggagcaag gcugcuggau cccugucagc ucagacaaag     3540

gcagcugucc ucaagugaug gaacgaucau uccauaugcc gucauacggg acacaaacgu     3600

uggaaggagg aguggaaaaa ccacauaguc uauuauccgc aaacccauua uggcaacaac     3660

gagcauuaga uccaccucau caaauggaau uaacucaaua aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  6819
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt6)

<400>  6819
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagcaggua gaagaaugga aauguuaugc gcaggaagag      120

uacccgcacu acuacuaugc cuaggauucc accuauuaca agcaguacua ucaacaacag      180

uaauaccaag cugcauacca ggagaaucau cagacaacug cacagcacua guacaaacag      240

aagacaaucc aagaguagca caaguaucaa uaaccaaaug cucaucagac augaacggau      300

acugcuuaca cggacaaugc auauaccuag uagacauguc acaaaacuac ugcagaugcg      360

aagucggaua cacaggagua agaugugaac acuuuuuucu aacaguacau caaccacuau      420

caaaagaaua cguagcacua acaguaauau uaauaauacu auuucuaaua acaguagucg      480

gaucaacaua cuacuucugc agaugguaca gaaacagaaa aucaaaagaa ccaaaaaaag      540

aauacgaaag aguaacauca ggagacccag aacuaccaca aguauaagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  6820
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt6)

<400>  6820
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagaaggag aaauaacaac auucacagca cuaacagaaa      120

aauucaaccu accaccagga aacuacaaaa aaccaaaacu acuauacugc ucaaacggag      180

gacacuuccu aagaauacua ccagacggaa caguagacgg aacaagagac agaagcgacc      240

aacacauaca acuacaacua ucagcagaau caguaggaga aguauacaua aaaucaacag      300

aaacaggaca auaccuagca auggacacag acggacuacu auacggauca caaacaccaa      360

acgaagaaug ccuauucuua gaaagacuag aagaaaacca cuacaacaca uacauaucaa      420

aaaaacaugc agaaaaaaac ugguucguag gacuaaaaaa aaacggauca uguaaaagag      480

gaccaagaac acacuacgga caaaaagcaa uacuauuccu accauuacca gucucaagcg      540

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  6821
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt6)

<400>  6821
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guugggguag gaggaggaga cguagaagau guaacaccaa      120

ggccaggagg augucaaaua agcggaagag gagcaagagg auguaauggg auaccaggag      180

cggcagcaug ggaagcugca uuaccaagaa gaagaccuag gagacaucca aguguuaauc      240

caagaucuag agcagcgggg aguccaagaa caagaggaag aagaacagaa gaaagaccaa      300

gugggucaag auuaggagau agagguaggg ggagagcauu accaggugga agauuaggag      360

guagaggaag aggaagagca ccagaaagag ugggaggaag aggaagggga agaggaacag      420

cagcaccaag agcagcacca gcugcaagag gaaguagacc agggccggca ggaacaaugg      480

cagcaggaag uauaacaaca uuaccagcau uaccagaaga cggaggauca ggagcauuuc      540

caccaggaca uuuuaaagac ccaaaaagau uauauuguaa aaacggagga uuuuuucuaa      600

gaauacaucc agauggaaga gucgauggug ugagggaaaa aagugauccg cauauaaaau      660

uacaauuaca agcagaagaa cgaggaguug uaaguauaaa aggaguaugu gcaaauagau      720

aucuagcaau gaaagaagau ggaagauuau uagcaaguaa auguguaaca gacgaauguu      780

uuuuuuuuga aagauuagaa agcaauaauu auaauacuua uagaaguaga aaauauacaa      840

gcugguaugu agcuuuaaaa agaacaggac aauauaaacu aggaaguaaa acaggaccag      900

gacaaaaagc aauacuauuu cuaccaauga gcgcaaaguc auaaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  6822
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt6)

<400>  6822
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uacuaacaug gauacuacca acacuacuau      120

acagaagcug cuuccacaua auaugccuag uaggaacaau aagccuagca ugcaacgaca      180

ugacaccaga acaaauggca acaaacguaa acugcucauc accagaacga cacacaagau      240

cauacgacua cauggaagga ggagacauac gaguaagaag acuauucugc agaacacaau      300

gguaccuaag aauagacaaa agaggaaaag uaaaaggcac ucaagaaaug aaaaacaacu      360

acaacauaau ggaaauaaga acaguagcag ucggaaucgu agcaauaaaa ggaguagaau      420

cagaauucua uuuagcaaug aacaaagaag gaaaacuaua cgcaaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa uuaauacuag aaaaccacua caacacauac gcaucagcca      540

aauggacaca caacggagga gaaauguucg uagcacuaaa ccaaaaagga auaccaguaa      600

gaggaaaaaa aacaaaaaaa gaacaaaaaa cagcacacuu ccuaccaaug gcaauaacau      660

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  6823
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt6)

<400>  6823
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuacuac caucaguagu acuaaaacua uuuuuagcag      120

caguacuauc agcacuagua acuggagaau cacuagaaag auuaagaaga ggacuagcag      180

caggaaccuc aaauccagac ccaccaacag uaagcacaga ccaauuauua ccacuaggag      240

gaggaagaga cagaaaagua agagaccuac aagaagcaga ccuagaccua uuaagaguaa      300

cacuaucauc aaaaccacaa gcacuagcaa caccaaacaa agaagaacac ggaaaaagaa      360

aaaaaaaagg aaaaggacua ggaaaaaaaa gagacccaug ccuaagaaaa uauaaagacu      420

ucugcauaca cggagaaugc aaauacguca aagaacuaag agcaccaagc ugcauaugcc      480

accccggaua ccauggagaa agaugccacg gacuaucacu accaguagaa aaccgacuau      540

acacauacga ucacacaaca auauuagcag uaguagcagu aguauuauca ucaguaugcu      600

uacuaguaau aguaggacua uuaauguuca gauaccacag acgaggagga uacgauguag      660

aaaaugaaga aaaaguaaaa cuaggaauga caaauucaca uuaaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  6824
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt6)

<400>  6824
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uggguaacua aacuuuuacc agcguuauua cuccaacacg      120

uauuacuaca ccuccuauua uuaccaauag cuauaccaua ugcagaagga caaagaaaac      180

gcagaaacac cauacaugaa uuuaaaaaau cggccaaaac aacucuaauc aaaauagauc      240

cagcauuaaa aauaaaaaca aaaaaaguua acacagccga ucaaugugca aaccgcugca      300

cacguaauaa aggccuacca uucacaugca aagcauuugu auuugauaaa gcacguaagc      360

aaugucuaug guuuccauuu aauagcauga gcucuggcgu aaaaaaagaa uuuggacaug      420

aauuugaccu auacgaaaau aaagacuaua uuagaaacug uauuauagga aaaggaagau      480

cauauaaggg cacaguaucc auaacaaaau caggaauuaa augucaacca uggucaucca      540

ugauacccca cgaacauuca uuuuuaccau caaguuauag aggaaaagau uuacaagaaa      600

acuauugccg aaacccaaga ggagaagaag gcggaccuug guguuuuaca ucaaacccag      660

aagucagaua ugaaguuugu gauauacccc aauguucaga aguagaaugu augacaugua      720

auggagaauc auauagaggu cuaauggauc acacagaaag ugguaagaua ugccaaagau      780

gggaucauca gacaccacac cgacauaaau uuuuacccga aagauacccu gauaaaggau      840

uugaugauaa uuacugucga aacccugaug ggcagccaag accauggugu uauacuuuag      900

acccccacac aagaugggaa uauugcgcua uaaaaacaug cgcggauaau acaaugaaug      960

auacagaugu acccuuagaa acuacugaau guauacaagg acaaggugag gguuaucgcg     1020

gcacugucaa uacuauaugg aauggcaucc ccugucaaag augggauuca caauaucccc     1080

augaacauga uaugacacca gaaaacuuua aauguaaaga uuuacgagaa aauuauugcc     1140

guaauccaga ugguucagaa ucucccuggu gcuuuacaac cgauccaaau aucagagucg     1200

gguacuguuc acagauacca aauugcgaca ugucucaugg ucaagauugu uauaggggaa     1260

acggaaaaaa uuauauggga aacuuaucuc aaacuagauc agguuuaacu uguaguaugu     1320

gggauaaaaa uauggaagau uuacacagac auauauucug ggaaccugau gcaagcaaac     1380

uaaacgaaaa cuacuguagg aauccagacg augaugcaca uggcccuugg ugcuauacag     1440

gaaauccauu aaucccgugg gauuauuguc ccauaucgcg augugaaggc gacacaacgc     1500

caacuauagu aaaccuagau cauccaguga uaucaugugc aaaaacuaaa caauuaagag     1560

ucguaaaugg aauaccaaca agaacaaaca uuggauggau gguaucacuc cgauacagaa     1620

auaaacauau auguggagga ucauuaauaa aagaaagcug gguuuuaacc gcaagacaau     1680

guuuuccauc ucgagaccuu aaagacuaug aagcaugguu aggaauacac gacguacaug     1740

guagaggaga cgaaaaaugu aaacaaguac uaaauguuuc ccaacuugua uaugguccag     1800

aagguucaga uuuaguauua augaaauuag cgagacccgc aguuuuagau gauuucguaa     1860

gcaccauaga ccuaccgaau uauggaugua cuauaccaga aaaaacaagu uguaguguau     1920

acggaugggg auauacaggc cuaauaaauu augacggauu acuaagaguc gcacacuuau     1980

auauaauggg aaacgaaaaa uguucacaac aucacagagg uaaaguaaca uuaaaugaaa     2040

gugaaauaug ugcaggagcu gaaaaaauag gcucaggacc gugugaagga gauuauggag     2100

gcccacuagu augugaacag cacaaaauga gaaugguacu aggaguaaua guaccaggcc     2160

gaggaugugc aaucccaaac agaccaggaa ucuuuguuag agucgcuuac uaugcuaaau     2220

ggauacauaa aauaauacua acauauaaag uaccacaauc auaaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  6825
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt6)

<400>  6825
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaaagcag cagcaauugg aauagauuug gguacaacau      120

acaguugcgu gggcguguuu caacacggaa aaguagaaau aauagcaaac gaucaaggaa      180

acaggacaac accaucauac guggcauuua cagacacaga acgauuaaua ggggacgcug      240

cuaaaaacca aguagcauua aacccccaaa acacaguguu cgaugcgaaa aggcuuauag      300

gucggaaauu uggggauccc guaguccaaa gcgauaugaa acauuggcca uuccaaguca      360

uuaaugaugg agauaaacca aaagugcaag uaaguuacaa gggugaaaca aaagcauuuu      420

acccggaaga aauaucaagu augguacuaa cuaaaaugaa ggaaauagcu gaagcauacc      480

uaggauaccc aguaacaaau gcgguaauaa cagugccagc cuacuuuaac gauucgcaac      540

gacaagcaac gaaagacgca ggggucauag ccggucuaaa ugucuuaaga auaauaaaug      600

aaccaacagc agcagcgaua gcuuacggac uagauagaac aggaaaaggu gaaagaaacg      660

uacuaauauu ugauuuggga ggaggaacau uugacguauc gauauuaacc auagaugacg      720

gcauauuuga aguaaaggca acggcaggag acacacaucu gggaggagaa gacuuugaua      780

aucggcuagu aaaucacuuu gucgaagaau uuaaaagaaa acacaagaaa gauauaaguc      840

aaaacaaaag agcaguaaga agacuuagaa ccgccugcga aagagcaaaa agaacacuaa      900

gcucaucaac acaagcaagu uuggaaauag auucauuauu ugaagguaua gacuucuaua      960

cuucaauuac aagagccaga uucgaagaac uauguaguga uuuauuuaga aguacguuag     1020

aaccgguaga aaaagcguua agagaugcua aacuagauaa agcucaaauc caugaucuag     1080

uauuaguagg aggaaguaca agaauaccaa aagugcaaaa auuacuucaa gauuucuuua     1140

acggaagaga ucuaaauaaa ucgauaaauc cagaugaagc gguagcguac ggagcagcag     1200

uacaagcagc aauauugaug ggagauaaaa gugaaaacgu ucaagauuua uuauuacuag     1260

auguagcccc auuaaguuua ggacucgaga cagcuggugg aguuaugaca gcgcuaauaa     1320

aaaggaacuc aacaauacca acaaaacaaa cacaaauauu uacaacauau agugauaauc     1380

aaccaggagu acuaauacaa guauaugaag gagaaagagc gaugacaaaa gacaauaauu     1440

uacuuggaag auucgaacuu aguggaauac caccagcacc acgaggagua ccacaaauag     1500

aaguaacguu ugauauugac gcaaacggaa uacuaaaugu aaccgcuaca gauaaaagca     1560

caggaaaagc aaacaaaaua acuauaacaa augauaaagg uagauuaagu aaagaagaaa     1620

uagaacguau gguacaagaa gcagaaaaau acaaagcaga agacgaagua caaagagaaa     1680

gggucagcgc gaaaaaugca cuagaaaguu acgcauucaa uaugaaaagu gcaguagaag     1740

augaaggacu caaaggaaaa auaagugaag cagauaaaaa gaaagucuua gauaaauguc     1800

aagaagugau aagcuggcua gaugcaaaua cauuagcuga aaaagacgaa uuugaacaua     1860

aaagaaaaga acuagagcaa guaugcaacc caauaauaag uggcuuguac caaggggcag     1920

gaggaccggg gccaggaggc uuuggagcuc aaggaccuaa aggaggaagc gguagcggac     1980

caacaauaga agaaguagac uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6826
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt6)

<400>  6826
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaaagcag cagcgauagg aauagauuua gggacaacuu      120

auaguugugu aggaguauuc caacauggaa aaguagaaau aauagcuaau gaccaaggaa      180

auagaacaac uccuaguuau guagcauuua cagacacaga aagacuaaua ggagacgccg      240

cuaaaaauca aguagcccuc aauccacaga auacaguauu cgacgcaaaa agacuuauag      300

guaggaaauu cggagaucca gugguacaaa gcgauaugaa acauuggcca uuucaaguaa      360

uaaaugacgg agauaaacca aaaguacaag uaucauacaa aggagaaaca aaagcauuuu      420

auccugaaga aaucucaagu augguacuaa caaagaugaa ggaaauugca gaagcauauc      480

uuggauaccc aguaacgaac gcaguaauaa caguaccugc cuacuuuaac gacagccaac      540

gucaagcaac uaaagacgca ggaguaauag cuggucuaaa cguacuuaga auuaucaaug      600

aaccaacugc agccgcaauc gcauacggac uagaccgaac gggaaaagga gaaaggaaug      660

uauuaauuuu cgaccuagga ggaggaacau ucgaugucuc uauauuaacu auagacgaug      720

gaauuuuuga aguaaaagca acggcaggag acacgcauuu aggaggagaa gauuucgaua      780

accgucuagu aaaucauuuc guugaagaau uuaaaagaaa acauaaaaag gacauuucgc      840

aaaauaaaag agcagugaga agauuaagaa ccgccuguga aagagcaaaa agaacauuaa      900

gcagcaguac gcaagcaagc cuugaaauag auucacuauu ugaaggaaua gauuucuaca      960

caucaauaac aagagcucga uuugaagaau uauguagcga cuuguucaga ucaacauuag     1020

agccaguaga aaaagcacua agagacgcaa aauuagacaa agcacaaaua caugaccuag     1080

uauuaguugg aggcaguaca cgaauaccaa aaguacaaaa acuucuacaa gacuucuuua     1140

auggaagaga ucuaaauaaa ucaauaaauc cagaugaagc aguagccuac ggugcggcgg     1200

uucaagcagc aauacugaug ggggacaaau cagaaaaugu acaagauuua uuauuauuag     1260

auguggcacc acuaucauua ggauuagaaa cagcuggagg uguaaugaca gcacuaauua     1320

aacgaaacag caccauacca acgaaacaaa cacaaauauu uaccacguac ucggacaauc     1380

aaccgggagu auugauacaa guauacgaag gagaaagagc aaugacuaaa gacaacaauc     1440

uauuaggaag auucgaauua ucaggaauac cgccagcacc aagaggagua ccacaaauag     1500

aaguaacauu cgauauagac gcaaauggca uuuuaaacgu aacagcaaca gacaaaucaa     1560

cagguaaagc aaacaaaaua acaauaacaa augauaaagg aagacuaucu aaagaagaaa     1620

uagaaagaau gguacaagaa gccgaaaaau acaaagcaga agaugaaguu caaagagaac     1680

gugugagugc caagaaugca cuugaaucgu augcguucaa uaugaaaagc gcaguagaag     1740

augagggccu aaaaggaaaa auaucagaag cagacaaaaa gaaagucuug gauaaguguc     1800

aagaaguaau aaguugguua gaugcaaaca cacucgcaga aaaagaugaa uuugaacaua     1860

aaagaaaaga acuagaacaa guaugcaauc caauaauauc aggguuauac caaggagcag     1920

gcggaccagg acccggggga uucggugccc agggaccaaa aggcgguagu ggcagcggac     1980

caaccauuga agaaguagau uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6827
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt6)

<400>  6827
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuacagcaa aaggaauagc aauaggaaua gauuuaggaa      120

caacauauuc guguguugga guauuccaac acggaaaagu agaaaucaua gcaaaugacc      180

aaggaaacag aacaacacca agcuauguag cauuuacgga uacagaaaga uuaauaggag      240

acgcagccaa aaaccaagua gcuaugaauc cacaaaauac aguauucgau gcaaaaagac      300

uaauaggaag aaaauuuaau gacccaguag uacaagcaga uaugaagcua uggcccuucc      360

aaguuauaaa ugaaggaggg aaaccaaaag uucuaguaag uuauaaaggu gaaaauaaag      420

ccuucuaucc agaagaaaua ucaagcaugg uccuaacaaa acuaaaagaa accgcagaag      480

cauucuuagg acauccuguc acuaacgcag uaauaacagu accagcauac uucaacgaua      540

gucaacguca agcaacaaaa gaugcuggag uuauagcagg acuaaaugua cuacgaauaa      600

ucaacgaacc gacagcagca gcuauagcau auggacucga caaaggcgga caaggagaaa      660

gacacgugcu caucuucgac uuaggcggug gcacauuuga uguauccaua cuaaccauug      720

acgauggaau uuucgaagua aaagccacag ccggagacac ccaucuaggg ggagaagauu      780

ucgauaaccg guuaguaagu cacuucguag aagaauuuaa aagaaaacac aagaaagaua      840

uaagucaaaa uaaacgagca guaagaagau uaagaacagc augugaaaga gccaaaagaa      900

cacuuaguag uucaacacaa gcaaacuuag aaauagauuc auuauacgaa ggaauagauu      960

ucuauaccag uauaacaaga gcaagauuug aagaacuaug cgcugauuua uuucgcggaa     1020

cauuagaacc cgucgaaaaa gcauuaagag augcaaaaau ggauaaagca aaaauacacg     1080

acauaguauu agugggaggu agcacgcgaa uaccaaaggu ucaacgauua uuacaagacu     1140

auuuuaaugg cagagaccuc aauaaaagua uaaacccuga ugaagcaguu gcauacggag     1200

cugcaguaca agcagcuaua cugaugggag acaaaucaga aaaaguacaa gaucuccuac     1260

uacuagacgu agcuccacua ucacuggguc uugagacagc gggaggcgua augacagcau     1320

uaauuaaaag gaacucgacc auacccacaa aacaaacaca aauauuuacc acauauucag     1380

auaaccaacc uggagugcuu auucaaguau acgaaggaga aagagcaaug acgaaagaua     1440

auaacuugcu aggaagauuu gaucuaacag ggauuccacc agcaccaaga ggcgugccac     1500

aaauagaagu caccuucgac auagacgcaa acggaauauu aaacgucaca gcaaccgaua     1560

aaucaacagg uaaggucaau aaaauuacaa uaacaaacga uaaaggaaga cuaucaaaag     1620

aagaaauaga aagaauggua cuagaugcag aaaaauacaa agcagaagac gaaguacaaa     1680

gagagaaaau agcagcuaaa aacgcgcuag aaaguuacgc auuuaacaug aaaaguguag     1740

uaucugauga aggauuaaaa ggcaaaauuu cagaaagcga uaaaaauaaa auacuagaca     1800

aaugcaauga acuacuuagu ugguuagaag uaaaucaacu agccgaaaag gaugaauuug     1860

accauaaaag aaaagaacug gaacaaaugu guaaucccau cauaacaaaa cuauaucaag     1920

gaggcugcac aggaccagca uguggaaccg gauauguacc aggacgucca gcaacaggac     1980

caacaauaga agaaguagac uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6828
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt6)

<400>  6828
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucagcaagag gaccagcaau ugggauagau cuaggcacaa      120

cuuacucaug cguaggugua uuccaacacg gaaaaguaga aauuauagca aacgaucaag      180

ggaacagaac aacaccaagu uauguagcau uuacagacac ugaaagauua auaggugacg      240

cagcuaaaaa ucaaguagca augaacccua caaacacaau uuuugacgca aaacgacuaa      300

ucggaagaaa auucgaagac gcaacaguac aaucagauau gaaacauugg ccguucagag      360

uaguaagcga aggagggaaa ccaaaaguac agguugaaua caaaggagaa acaaaaacuu      420

ucuucccaga agaaauuagu aguauggucc ucacaaaaau gaaagaaaua gcagaagcau      480

accuuggagg aaaaguucac ucagcaguaa uuacaguacc agcauacuuc aacgauuccc      540

aaagacaagc aacgaaagac gccgguacaa uaacaggauu aaacguguua agaauuauaa      600

acgaaccuac cgcagcagcc auagcguaug gauuagauaa gaaaggaugu gcaggaggag      660

agaaaaaugu auuaauauuu gacuuaggcg gugggacauu ugauguaagu auacugacaa      720

uagaagaugg gauauuugaa gucaaaucga cagcaggaga cacacauuua gggggagaag      780

acuuugacaa cagaauggua agccaucuag cagaagaguu caaaagaaaa cacaagaaag      840

acauaggacc caauaaaaga gcugucagga gacuuagaac agcaugcgaa agagcaaaaa      900

gaacauuauc aaguucaaca caagcaagua uagaaauaga uucgcuauau gaaggaguug      960

auuucuauac aaguauaaca agagcaagau uugaagaacu aaacgccgau cuauuuagag     1020

gaacauuaga accgguugaa aaagcacuua gagacgcaaa auuggauaaa ggccaaauac     1080

aagaaauugu ucuaguagga ggaaguacac gcauuccaaa aauacaaaaa cuauuacaag     1140

acuuuuucaa uggaaaagaa cucaauaaau caauaaaccc ugaugaagcg guagcguaug     1200

gugcagccgu acaagccgca auauuaaucg gagacaaaag ugaaaacgua caagaccuac     1260

uauuguuaga uguaacacca uuaucacucg gaauugaaac agcuggagga guaaugacac     1320

cacucauaaa aagaaauaca accauuccca caaaacaaac acaaacauuc acaacguaca     1380

gcgauaacca aaguagcguc cuaguacaag uauaugaagg cgaaagagca augaccaaag     1440

acaacaaucu auuaggaaaa uucgacuuaa caggaauacc uccagcacca aggggaguac     1500

cacaaauaga aguuacauuu gacauagaug cuaacggaau auuaaacgua acagcagcag     1560

auaaaagcac aggaaaagag aauaaaauaa caauuacaaa cgauaaagga agacuaagca     1620

aagacgauau agauagaaug guacaagaag cagaaagaua uaaaagcgaa gacgaagcua     1680

acagggaucg agucgcagcc aaaaaugcau uggaaagcua uacauacaau auaaaacaaa     1740

cuguagaaga ugaaaaauua agaggaaaga uaagugaaca agauaaaaau aaaauuuuag     1800

acaaauguca agaaguuaua aacugguuag auagaaacca aauggccgaa aaagacgagu     1860

acgaacauaa acaaaaagaa cuagaaagag ucuguaaucc cauaauuagc aaauuauacc     1920

aaggaggacc cggaggugga aguggaggag gaggaucagg agcaagcgga ggcccaacaa     1980

uagaagaggu ugauuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  6829
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt6)

<400>  6829
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgugguag guauagaucu uggauuccaa ucauguuacg      120

uugccguagc aagagcagga ggaauagaaa caauagccaa cgaauacagu gacagaugua      180

caccggccug cauauccuuu ggaccuaaaa acagaucaau cggcgcagcc gcaaaaucac      240

aagugauuuc aaaugcuaaa aacacagugc aagguuucaa aagauuccac ggacgagcau      300

uuagcgaccc auuuguugaa gcagaaaaau caaacuuagc uuaugauauc guacaauuac      360

ccacaggacu aacagguaua aaagucacau auauggaaga ggaaagaaac uucacaaccg      420

aacaaguaac cgcgaugcua uuaucaaaac ucaaagaaac agcagaaucc gucuuaaaga      480

aaccugucgu ugacugugua guaucaguac ccugcuucua cacagacgca gaaagaagau      540

ccguaaugga ugccacacaa auagcugguc ugaauugcuu acgacuaaug aaugaaacga      600

cggcaguugc auuagcuuac ggaauauaua aacaagacuu acccgcacua gaagaaaaac      660

caagaaacgu cguauuugua gauauggguc acagugcaua ucaagugucc guaugugcuu      720

uuaacagagg uaaacuaaaa guauuagcaa cagcuuuuga uacuacuuua ggcggacgaa      780

aauuugauga aguucuagua aaucauuuuu gcgaagaauu ugguaagaaa uacaaacucg      840

auaucaaauc aaaaauacgu gcauuauuac gacuuucaca agaaugugaa aaacuaaaga      900

aauuaaugag ugcaaacgca agcgaccugc cuuuaucuau agaauguuuc augaacgaug      960

uagauguauc gggcacaaug aacagaggua aauuccucga aaugugcaac gaucuguuag     1020

caagaguaga accaccacua cgaaguguau uagaacaaac aaaacuaaag aaagaagaca     1080

uuuaugcagu agaaauaguu ggaggggcaa cacgaauacc agcgguaaaa gagaaaauuu     1140

caaaauucuu uggcaaagaa uuaucaacua cacuuaaugc agaugaagcc guaacuagag     1200

gaugugcacu ccaaugugca auauuaucac cagcuuucaa aguaagagaa uuuagcauaa     1260

cagauguagu accauaccca auuucacuga gauggaacuc accagcagaa gaagggucau     1320

ccgacugcga aguauucagu aaaaaucaug cugccccuuu uucaaaagua cuaacauucu     1380

auagaaaaga accuuuuacc cuagaagcau acuauucauc accccaagau cuuccauacc     1440

ccgauccagc aauagcccaa uuuagcgugc aaaaaguuac accucaaagu gauggaucaa     1500

gcaguaaagu uaaaguaaaa guccguguga acguucaugg uauauuuagu guaucuucag     1560

ccagccuagu agaaguacac aaaagcgaag aaaaugaaga accaauggaa acggaucaaa     1620

augcuaaaga agaagagaaa augcaaguag accaagaaga accacaugua gaggaacaac     1680

aacaacaaac acccgcagaa aacaaagccg aaagugaaga aauggaaaca ucucaagcag     1740

gaucaaagga uaagaaaaug gaucaaccuc cucaagcgaa gaaagcaaaa guaaaaacau     1800

cuacagucga ucuuccaaua gaaaaccaac uuuuauggca aaucgauaga gaaauguuaa     1860

accuauauau agaaaacgaa ggaaaaauga uaaugcaaga caaauuagaa aaagaaagaa     1920

acgacgcuaa aaacgcagua gaagaauaug uuuaugaaau gagagauaaa cugagcggag     1980

aauacgaaaa auucguaagc gaagacgauc gaaauucauu cacccuaaaa cuugaagaca     2040

cugaaaacug gcucuacgaa gauggagaag accaaccaaa acaaguauac guagauaaac     2100

uagcagaacu gaaaaaccua ggacaaccaa uaaaaauaag auuccaagaa agugaagaac     2160

guccuaaauu auucgaagaa cuaggaaaac aaauacaaca auauaugaaa aucauaucaa     2220

guuuuaaaaa caaagaagau caauacgacc acuuagaugc cgcagacaug acaaaaguag     2280

aaaaaucuac uaacgaagcc auggaaugga ugaauaauaa auuaaaccuc cagaacaaac     2340

aaucgcuaac aauggaucca guggucaaau caaaagaaau agaagcaaaa auuaaagaac     2400

uaacaaguac uugcucacca aucauaagca aaccaaaacc caaagucgaa ccaccaaaag     2460

aagaacagaa aaacgcagaa caaaauggac caguagacgg ccaaggugac aacccaggac     2520

cacaagcagc ggaacaaggu acugacacag caguacccuc agacagugau aagaaacuac     2580

cagaaaugga uauagacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  6830
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt6)

<400>  6830
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaguagucg gaauugaccu uggauuuuua aacugcuaca      120

uagcaguagc uaggucagga ggaaucgaaa caauagcaaa cgaauauagc gauagaugca      180

ccccugccug cauaucauua ggaucacgca cuagagcaau cgggaacgca gccaaaucac      240

aaauaguuac aaacguaaga aauacaaucc acggauucaa aaaacuacac ggcagguccu      300

uugaugaucc aauaguacaa acggaaagaa uaagacuacc cuacgaacug caaaaaaugc      360

ccaauggaag ugcaggcguc aaagucagau aucuagaaga agaaagaccu uuugcaauag      420

aacaaguaac cggaauguua uuggcuaagc uaaaagaaac uucagaaaac gcauuaaaga      480

aaccuguagc agauuguguu auaucaauac caucguuuuu cacagaugca gaacgaagau      540

caguaauggc agcagcacaa guagccggcc uaaacugucu ucgacuaaug aaugaaacaa      600

cugcaguugc ccuagcuuau ggaauuuaua aacaagauuu accuccucua gacgaaaaac      660

ccaggaacgu aguauucaua gauauggguc auagugcaua ucaaguucua gugugugcau      720

uuaauaaagg aaaauuaaaa guccuagcaa caacauucga uccguaucua ggagggcgaa      780

acuucgauga ggcacuggua gacuacuuuu gugacgaauu caaaacgaaa uacaagauua      840

acguaaaaga aaacagcaga gcucuucuaa ggcuauacca agaaugugaa aaacucaaaa      900

aauuaauguc cgcuaaugcc ucagaccuac cacuaaauau agaauguuuc augaaugauu      960

uagauguguc aaguaaaaug aacagagcac aauuugaaca auuaugcgca ucauuacuag     1020

cucgaguaga accaccauua aaagccguaa uggaacaagc uaauuuacaa cgagaagaua     1080

ucucaucaau agaaaucguu ggaggagcca ccagaauucc agcgguaaaa gaacaaauua     1140

cuaaauuuuu ucuuaaagac aucucaacaa cacuaaaugc ugacgaagca guugcccggg     1200

gaugcgcccu ccaaugugca auacuuagcc cugcauuuaa aguacgagaa uuuucaauaa     1260

cagacuuagu uccauauucg aucacauuaa gauggaaaac aucauucgaa gacggcagcg     1320

gcgaauguga aguauucugc aaaaaccacc cagccccuuu uagcaaagua auaacauuuc     1380

auaaaaaaga accguuugaa uuagaagcau uuuacacaaa cuuacacgaa guaccauacc     1440

cugaugcacg aauagguagc uuuacuauac aaaacguauu cccacaaucc gauggcgaca     1500

gcucaaaagu uaaaguaaaa gucagaguaa acauacaugg aauuuucucu gucgcaucag     1560

caucuguuau cgaaaaacaa aaucuagaag gggaccauuc cgacgcccca auggaaaccg     1620

aaacaagcuu uaaaaaugaa aacaaagaca auauggauaa aaugcaagua gaucaagaag     1680

aaggacauca aaaaugccau gcugagcaua caccagaaga agagauagac cacacugggg     1740

caaaaacaaa aucagccguu ucagauaaac aagauagauu aaaucaaaca cuaaaaaaag     1800

gcaagguaaa aucuauugau uuaccaaucc aauccucacu cugcagacaa uuaggacaag     1860

aucuauuaaa uagcuauaua gaaaaugaag gaaaaaugau caugcaagac aaacuagaaa     1920

aagaaagaaa cgacgccaaa aaugcaguug aagaauacgu auaugauuuc agggaccgac     1980

uaggaaccgu uuaugaaaaa uuuauaacgc cagaagaccu uucaaaacua agugcaguau     2040

uagaagacac agagaacugg uuauaugaag auggagaaga ccaaccaaaa caaguauacg     2100

uugacaaauu acaagaacua aagaaauacg gacaaccaau acaaaugaaa uacauggagc     2160

acgaagaacg uccaaaagca cuaaacgacc uaggcaaaaa gauccaacuu guaaugaaag     2220

uaauagaagc uuauagaaau aaagaugaac gguaugacca ucuugacccc acagaaaugg     2280

aaaaaguuga aaaaugcaua agcgacgcaa ugagcuggcu caacagcaaa augaacgcac     2340

aaaacaaauu aucacuaaca caagauccag uaguaaaagu cagugaaaua guagcaaaau     2400

caaaagaacu agacaauuuc uguaauccaa uaauauacaa acccaaacca aaagccgaag     2460

uccccgaaga caaaccaaaa gcaaacucag aacauaaugg uccaauggau ggacaaucug     2520

gaacagagac aaaaucagac ucaacuaaag auucauccca acauaccaag aguagcgggg     2580

aaauggaagu cgacuaggga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  6831
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt6)

<400>  6831
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauuaaguu ugguggcagc aaugcuauua uuauuaagcg      120

cugcaagagc agaagaagag gauaaaaaag aagauguugg uacggugguu ggaauugacc      180

uuggaacaac auacagcugu gucggaguau uuaaaaaugg aagaguugaa auuauagcua      240

acgaucaggg gaauagaaua acaccaaguu acguagcauu cacaccagag ggagaaagau      300

uaaucggaga cgcagcaaaa aaccaacuua cuaguaaucc agaaaauaca guauucgaug      360

caaaaagauu aauaggaaga acauggaacg acccuuccgu acaacaagau aucaaauucc      420

uaccauuuaa aguuguagaa aaaaagacaa aaccauacau acaagucgau auaggaggag      480

gacaaacaaa aacauuugcg ccagaggaaa ucagugcaau gguauuaacu aaaaugaaag      540

agacagcaga agcauacuua gguaaaaaag uaacacacgc aguagucaca guaccagcau      600

auuuuaacga cgcacaaaga caagcaacaa aggaugcagg aacaaucgca ggauuaaacg      660

uaaugagaau aauaaaugag ccaacagcag cagcaauugc auauggauua gacaaacgag      720

aaggugagaa aaacauccug guauucgacu uaggaggggg cacauuugac guaaguuuau      780

uaacuauaga uaauggagua uuugaaguag uagcaacaaa cggugacaca cauuuaggag      840

gagaagauuu cgaucagaga guaauggaac auuuuauaaa auuauacaaa aaaaaaacag      900

gaaaagaugu aaggaaagac aauagagcag ugcaaaaacu uaggagagaa gucgaaaaag      960

caaaacgagc ccuaaguagc caacaucaag caagaauaga aauagaaagc uuuuaugaag     1020

gggaagacuu cagugaaaca cuuacgagag caaaauuuga agaauuaaac auggaccuau     1080

uuagaagcac aaugaaaccu guacaaaaag ugcucgaaga uucagaccua aaaaaaagcg     1140

acauagauga gauugucuua guaggaggaa guacaagaau uccaaaaauc caacaacuag     1200

uaaaagaauu uuucaaugga aaagaaccua guagaggaau aaacccagac gaagcaguag     1260

cauauggagc ugcaguacaa gcuggaguuc uaaguggcga ccaagacaca ggagacuuag     1320

uauuacuaga cguauguccg uuaacauuag gaauagaaac aguaggagga guaaugacca     1380

aauugauacc uaggaacacu guuguaccaa cgaaaaaauc acaaauauuu aguacagcau     1440

cagauaacca accaacugua acuauaaaag uauacgaagg agaaaggccu cuaacaaaag     1500

acaaucaccu ucugggaacc uuugaucuca caggaauacc accagcacca cggggaguac     1560

cgcaaauaga aguaacauuc gaaauagacg ucaacgguau ucuaagagua acggccgaag     1620

auaaaggaac aggaaacaag aauaagauaa cuauuacaaa ugaccaaaau cgauuaacuc     1680

cagaagaaau agaacgaaug gucaacgacg cagaaaaauu ugccgaagaa gauaaaaaau     1740

uaaaagagag aauagauacu cgaaacgaac uagaaaguua cgccuacuca cucaaaaacc     1800

aaaucgggga uaaagaaaag uuaggaggua aauuaucaag ugaagauaaa gaaacaaugg     1860

aaaaagcagu cgaagaaaaa auugaauggc uagaaucaca ccaagacgca gauauagaag     1920

auuucaaagc aaaaaaaaaa gaauuagaag aaauuguaca acccauaauu aguaaauuau     1980

auggaagugc agggccacca ccaacaggcg aagaagacac agcagaaaaa gaugaauuau     2040

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  6832
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt6)

<400>  6832
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcaccaa gagaacuagc gguaggaaua gauuuaggaa      120

caacuuacuc auguguagga guauuucaac aaggaagagu agaaauauua gcaaaugacc      180

aaggaaauag aacaacaccc ucauacguag ccuuuacaga caccgaacga uuaguaggag      240

augcagcaaa aagccaagca gcacucaacc cacauaauac ggucuuugac gcaaaaagau      300

uaauaggccg aaaauuugcg gauacuacag uacaaaguga uaugaaacac uggcccuuuc      360

gaguaguauc ugaaggagga aaaccgaagg uaagaguaug uuaucgagga gaagacaaaa      420

cauucuaucc agaagaaaua ucuucuaugg uauugucgaa aaugaaagaa acggcugaag      480

cguaucuagg acaaccagua aaacaugcag uaauaacugu accagcuuac uuuaaugaua      540

gccagagaca agcaacaaaa gaugcaggag ccauagcagg auuaaaugua uugaggauaa      600

uaaaugaacc aacugcagcc gcaauagcau acggguuaga ccgaagagga gccggugaaa      660

gaaaugucuu aauauuugau uugggcggag gaacauuuga uguaagugua uuaucaauag      720

acgcaggagu uuuugaaguc aaagcaacgg caggagacac acauuuagga ggggaagacu      780

uugauaauag gcuaguaaau cauuucaugg aagaauuucg aagaaaacac ggaaaagauu      840

uaucuggaaa uaaacgagcu uuaagaaggu uaagaacagc cugugaaaga gcaaaaagaa      900

cauuaucauc aaguacacaa gcaacauuag aaauugacuc acucuucgaa ggagucgacu      960

ucuauacauc aauaacacga gcaagauuug aagaacuaug cucagaucua uuucgaucaa     1020

cauuagaacc aguggaaaaa gcauugcggg augcgaaauu agacaaagca caaauacaug     1080

acguaguuuu aguaggcggc ucaacaagaa uaccaaaagu gcaaaaacua uuacaagauu     1140

ucuucaacgg gaaagaauua aacaaaucaa uuaauccgga ugaagcugua gcuuauggag     1200

cagcaguuca agccgccguc uuaaugggag acaaaugcga aaaaguucaa gauuuauuac     1260

uacuagaugu ggcaccacuc ucucuugguc ucgaaacagc gggaggaguu augacuacgu     1320

uaauccaaag aaaugcaaca auuccaacaa aacaaaccca gacauucaca acauacucug     1380

auaaucaacc aggagucuuu auacaaguuu acgaaggcga acgagcaaug acaaaagaua     1440

auaauuuauu gggaagauuu gaacuuucag gaauaccccc agcaccuaga ggaguaccuc     1500

aaauagaagu aaccuucgac auagacgcua auggaauacu uagcguaacu gcaacugaua     1560

gaaguacagg aaaagcaaac aaaauaacaa uaacaaacga uaaaggccga cuaagcaaag     1620

aagaaguaga aagaauggua caugaagcug aacaauacaa agccgaagau gaagcacaac     1680

gagauagagu ugcagcuaaa aauagucuag aggcacaugu auuucaugua aaaggcagcc     1740

uacaagaaga gagcuuaaga gacaaaauac cagaagaaga cagaagaaaa augcaagaua     1800

aguguagaga aguauuggca ugguuagaac auaaucaauu agcagaaaaa gaagaauaug     1860

aacaucaaaa acgagaauua gaacaaauau gucgaccaau auuuucaagg uuauauggag     1920

gcccaggagu accaggggga aguucaugug guacacaagc aagacaaggu gauccgucaa     1980

caggaccaau caucgaagaa guagacuaag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  6833
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt6)

<400>  6833
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcaccaa gagaauuagc uguaggaaua gacuuaggaa      120

caacauauuc cuguguagga guauuucaac aaggaagagu agaaauuuua gcaaaugauc      180

aaggaaauag aacaacacca ucauauguag cauuuacuga uaccgaaaga uuagucggag      240

augcagcaaa gucacaagca gcauuaaauc cucacaauac aguuuuugau gcaaaaagau      300

uaauaggaag aaaauucgcu gauacaacag uacaaagcga caugaaacau uggccauucc      360

aaguuguaag cgaaggugga aaaccaaaag uacgaguaug uuauagagga gaagacaaaa      420

cauucuaccc cgaagaaaua ucaaguaugg uucuaucaaa aaugaaagaa acagcagaag      480

cauauuuagg acaaccaguu aaacaugcag uaauaaccgu uccaacauau uuuagcaaua      540

gucaaagaca agcaacuaaa gaugcaggag caauagcagg acuuaaagua cugccaauaa      600

uaaaugaagc aacagcagca gcaauagccu auggccuaga cagaagagga gcuggaaaaa      660

gaaacguauu aauauuugau uuaggaggag gaacuuuuga uguaagugua uuaaguauug      720

acgcaggcgu uuuugaagua aaagcaacug cuggugauac ucacuugggu ggagaagauu      780

uugauaauag auuaguaaau cauuuuaugg aagaauuuag aagaaaacac ggaaaagauc      840

uaaguggaaa uaaaagggca uugagaagau uaagaacagc augugaaaga gcaaaaagaa      900

caccuagcuc aaguacacaa gcaacgcuag aaauagauuc auuauucgaa ggaguagauu      960

uuuauaaauc aaucacaagg gcaagauuug aagaauuaug cagugacuua uucaggagca     1020

cauuagaacc aguagaaaaa gcauuaagag augcaaaauu agauaaagca caaauacaug     1080

auuuugugcu aggaggggga uuacauucac auccacaagg agcagaaguu gcagcaggau     1140

uauuacaaag acaaggagca gaacaagaac accaaccaua aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  6834
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt6)

<400>  6834
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaaagggc cagcaguagg aauagauuua gguaccaccu      120

acagcugugu aggaguauuc caacacggaa aaguggaaau aauagcaaau gaccaaggca      180

auaggacaac accaucauac guugcauuca cagauaccga gcgacuaauu ggagaugcag      240

cuaaaaauca aguagcaaug aauccaacaa auacgguauu ugacgcaaaa agacuaauag      300

gcaggagguu ugaugacgca guuguacaaa gcgauaugaa acacuggcca uuuaugguag      360

uaaaugaugc uggaagacca aaaguacaag uagaauacaa aggcgaaacu aaaaguuucu      420

accccgaaga aguaucuuca augguauuaa caaaaaugaa agaaaucgca gaagcauacu      480

uaggaaaaac gguuacaaac gcaguaguaa caguaccagc auauuuuaac gacucccaaa      540

ggcaagcaac aaaagacgcu gggacaauug ccgggcuuaa uguauuaaga aucauaaaug      600

aaccaacagc agcagcaaua gccuacggau uagauaagaa aguaggugca gaaagaaacg      660

uauuaauauu ugacuuaggc gguggaacau uugauguauc aauauuaaca auagaagacg      720

gaauauuuga aguaaaaucu acagcuggag acacacaccu aggaggagaa gauuucgaua      780

acagaauggu aaaucauuuu auagccgaau uuaaaaggaa acauaagaaa gauauaagug      840

aaaauaaaag agcaguaaga agauuaagaa cagcaugcga gcgagcgaaa aggacuuuau      900

caucgagcac acaagcaagc auagaaauug auagccuaua ugaagguaua gacuuuuaca      960

caucaauaac aagagcccga uucgaagaau uaaacgcaga ucuauuuaga ggaacguuag     1020

acccaguaga aaaagcauua agagaugcaa aauuagauaa aagccaaaua caugacaucg     1080

uauugguugg aggaucuaca agaauaccua aaauacaaaa auuacuacaa gacuucuuua     1140

acggcaaaga auuaaacaaa ucaauaaauc cagacgaagc aguagcguau ggugcggcgg     1200

uacaagccgc uauauuaucc ggagacaaaa gugaaaacgu acaagaucua cuauuacuag     1260

acguaacacc ccuaucauua ggaauugaaa cagcaggagg aguaaugaca guuuuaauaa     1320

aaagaaauac aacaauacca acuaaacaaa cccaaacauu uacaacuuac agugacaauc     1380

aaccaggagu gcucauacaa guuuacgaag gagaacgagc aaugacaaaa gacaacaauc     1440

uauuaggaaa auuugaacua accggaauac caccagcacc uagaggcgug ccacaaauag     1500

aagucacauu ugacauagau gcaaauggaa uacuaaacgu cagcgcaguc gauaaaucaa     1560

caggaaaaga aaacaaaaua accauaacaa acgacaaagg acgccugagc aaagaagaua     1620

ucgaacgaau gguacaagaa gcagaaaaau auaaagcgga ggacgaaaaa caacgagaca     1680

aaguaagcag uaaaaacagc uuagaaucau augcauuuaa uaugaaagca acuguagaag     1740

acgaaaaauu acaaggaaaa auaaacgaug aagauaaaca gaaaauacua gacaaaugua     1800

acgagauaau aaauuggcug gacaaaaauc aaacggcaga aaaagaagaa uuugaacauc     1860

aacaaaaaga gcuugaaaaa guuuguaauc caauaauaac aaaacuauau caaagugcag     1920

gaggaaugcc aggaggaaug cccggaggau ucccuggagg aggcgcaccc ccaaguggag     1980

gagccaguuc aggcccaaca auagaagaag uagauuaggg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  6835
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt6)

<400>  6835
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaucagcaa gcagagcagc agcagcaaga cuugugggag      120

cagcagcauc aagaggaccu acagcagcaa ggcaucaaga uucguggaau ggguuaagcc      180

augaggcguu uagacuugug ucuaggagag auuacgccag cgaagcaauu aaaggugcgg      240

uuguaggaau agaucuagga acgacaaacu cauguguagc agucauggaa ggaaaacaag      300

caaaagugcu agaaaaugca gaaggcgcaa gaacaacacc aucaguaguu gcauuuacag      360

cagauggaga aagguuaguu gguaugccag caaaaagaca agcaguaaca aauccgaaca      420

auacauuuua cgcuacaaaa agguuaauag gaagaagaua cgaugaccca gaagugcaaa      480

aagauauuaa aaauguaccu uuuaaaauag ucagagcauc uaauggugau gcauggguag      540

aggcccacgg aaaacucuac ucuccaaguc aaauaggagc cuucguauua augaagauga      600

aagaaacagc ugaaaauuau uuaggacaca cagcgaaaaa ugcaguaaua acgguaccag      660

cauacuucaa cgacagucaa agacaggcaa caaaagacgc aggacaaaua aguggauuaa      720

acguauuaag aguaauaaau gaaccuacag cagcagcauu agcauauggc cuagauaaau      780

cagaagacaa aguaauagcg guauaugauu uaggcggagg aacauuugac auuucaauau      840

uagagauaca aaaaggugua uuugaaguua aaaguacaaa uggugacaca uuuuugggag      900

gagaagauuu cgaucaagca cuacuucgac auauaguuaa agaguuuaaa agagaaacag      960

ggguagaucu cacuaaagau aauauggcau ugcaaagggu aagggaagca gcugaaaaag     1020

caaagugcga gcuaagcuca ucuguacaaa cggauauuaa ucuaccauau uuaacaaugg     1080

acagcucagg uccaaaacau cucaauauga aauuaacaag agcucaauuc gaaggaauag     1140

uaacggacuu aauaagaaga acuauagcac caugucaaaa agcuaugcag gaugcggaag     1200

ugagcaagag ugacauagga gaaguuaucu ugguaggugg aaugacaaga augccaaaag     1260

uucaacagac aguacaagau cuauucggga gagcuccuag uaaagcuguu aauccagacg     1320

aagccguagc cauaggagca gcaauacaag gaggaguauu agcaggagau guaacugaug     1380

uacuacuauu agauguaaca ccguugagcc uuggaauaga aacuuuagga ggaguguuca     1440

cuaaauuaau caauagaaau acaacgauac cuacgaagaa aucacaagua uucaguacag     1500

cagccgaugg gcaaacacaa guagaaauaa aagucugcca aggagaaaga gagauggcag     1560

gagauaauaa auuguuaggg caauuuacau uaauagguau accuccagca ccgagaggag     1620

uaccucagau agaaguuaca uucgauauag augcaaaugg uauaguucau guaucagcaa     1680

aagacaaagg aacuggaaga gaacaacaaa uagugauaca aagcagugga ggacuaagua     1740

aagaugauau agaaaacaug guuaaaaacg cggaaaaaua ugcagaagaa gauagaagaa     1800

agaaagagag aguagaagca guuaacaugg cugaaggaau aauacaugac acugaaacaa     1860

aaauggaaga auuuaaagau cagcuaccag cagaugaaug uaauaaacua aaagaggaaa     1920

uaaguaaaau gagagaauug uuagcuagaa aagacaguga gacuggagaa aauauuagac     1980

aagcagcaag cucauuacaa caagcaagcc ucaaauuauu ugagauggca uauaagaaaa     2040

uggcaucaga aagggaagga uccggaucaa gcggaacggg agaacaaaaa gaagaucaaa     2100

aagaagaaaa acaauaggga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  6836
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt6)

<400>  6836
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagacaaag aagcaggcgg aagugauggg ccaagagaaa      120

cagcaccaac aucagcauac aguucaccag caagaagccu aggagacaca ggaauaaccc      180

cauuaagucc aucgcacauu guaaacgaca cagacuccaa cguaagcgaa caacaaaguu      240

uccuaguagu aguagcugua gauuuuggaa ccacaucauc aggauacgca uacucauuua      300

caaaagaacc ugaauguaua caugucauga gaagauggga aggcggagau ccuggaguaa      360

guaaucaaaa aacuccaaca acaauacuuc ucacaccaga acgaaaauuc cacucauuug      420

gauaugcagc cagagacuuu uaccacgauu uagauccaaa ugaagcaaaa caaugguuau      480

accuagaaaa auucaaaaug aaacuucaua ccacuggaga uuuaacaaug gacacagacc      540

uaacagcagc caauggaaaa aaaguaaaag cacuagagau auuugcauac gcacuacaau      600

acuuuaaaga acaagcacua aaagaauuaa gcgaccaagc agguuccgaa uuugaaaauu      660

cagacguaag auggguaaua acaguccccg caauauggaa acaacccgcc aagcaauuua      720

ugagacaggc agcauaccaa gcgggacuag ccuccccaga aaacucagaa caacuaauua      780

uagcacuuga accagaggca gcgucaauau auuguagaaa acuacgauua caucaaauga      840

uagaauuaag uucaaaagca gcaguaaaug gauacucagg aucagauaca gugggagcag      900

gauuuacaca agcuaaagaa cauauuagaa gaaacagaca aagcagaaca uuucuuguag      960

aaaacgucau aggagaaaua ugguccgaac uagaagaagg agauaaauau guaguaguug     1020

acagcggagg aggaacagua gaucuaacug uccaucaaau cagacuaccc gaagggcacu     1080

uaaaggaacu auacaaagca acgggaggcc cauacggcuc auuaggaguu gacuacgaau     1140

ucgaaaaauu auuauacaaa auauucggag aagauuuuau agaacaauuu aaaaucaaaa     1200

ggccugcagc auggguagau uuaaugauag cauuugaaag cagaaaaaga gccgcagcac     1260

ccgauagaac aaacccacua aauauaacac uaccguucuc auuuauagau uacuauaaaa     1320

aauuuagagg acauucggua gaacaugcac uaagaaaaag caacguugac uuugucaaau     1380

ggagcaguca aggaauguua cggaugagcc cagaugcaau gaaugcacua uucaaaccaa     1440

caauagauag uaucauagaa cauuuaagag auuuauuuca aaaaccagaa gucaguacag     1500

uaaaauuccu auucuuagua ggcggauucg cagaagcacc ccuauuacaa caagccguac     1560

aagcagcauu cggagaucaa uguagaauaa uaaucccaca agaugucgga cucacaauac     1620

ucaaaggagc aguucuauuc ggacucgacc cagcaguaau uaaaguaaga agaucaccac     1680

uuaccuaugg uguuggugua uuaaauagau auguagaagg aaaacacccu ccagaaaaau     1740

uauuaguaaa agauggaaca agauggugca cugacguauu ugauaaauuu auuucggcag     1800

accaaucagu agcucuaggu gaacuuguaa aacgauccua uacaccugca aaaccaucac     1860

aacuagucau aguaauaaau auauacuccu cagaacacga uaaugucuca uuuaucacug     1920

acccaggagu aaaaaaaugu ggcacauuaa gauuagauuu gacagguaca agugguacug     1980

caguacccgc acgaagagaa auccagacau uaaugcaauu uggcgacaca gaaaucaaag     2040

ccacagcaau agacauagcc acaucuaaau caguaaaagu aggaauagac uucuuaaauu     2100

auuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  6837
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt6)

<400>  6837
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuugcaguuc cagaaauggg acuacaagga cuauauauag      120

gcaguucacc agaacgaagu ccgguaccca guccaccggg aucaccaagg acacaagaaa      180

guugcggaau agcaccucua acaccuagcc aaucaccuaa accugaagug agagcaccac      240

aacaagcgag uuucucgguu guaguagcaa uagauuucgg aacaacauca agugguuaug      300

cauuuucauu ugcuucagau ccagaagcua uacauaugau gcgaaaaugg gaaggaggcg      360

auccuggcgu agcacaucag aaaaccccua cuugucuauu gcuaacacca gaaggagcau      420

uucauaguuu uggauauacc gcucgagauu acuaucauga cuuagaucca gaagaagcaa      480

gggauugguu auacuuugaa aaauuuaaaa ugaaaauaca uagugccacg gaucuaacau      540

uaaaaacaca auuagaagca guaaauggaa aaacaaugcc agcauuagaa guauuugcac      600

acgcauugag auucuuucgc gaacaugccu uacaagaacu acgcgaacaa uccccuuccu      660

uaccagaaaa ggauacugua cgauggguau uaacaguccc cgcuauaugg aaacaaccgg      720

cuaaacaauu uaugagagaa gcagcauauu uggcuggccu agucagccgg gaaaacgcug      780

aacaauuacu aauagcauua gaaccagaag cugcaagcgu auacuguaga aaacuaagac      840

uucaucaauu acuagaucua agcggaaggg caccuggagg agggcgauua ggagaaagaa      900

gaucuauaga uucaucauuu agacaagcua gagaacaauu aagaagauca cgucacucaa      960

gaacauuucu aguugaauca gguguaggcg aacuuugggc agaaaugcaa gcaggagaca     1020

gauauguagu ggcugacugc ggagggggua caguugaccu aacaguacau caauuagaac     1080

aaccacacgg aacacuaaaa gaauuauaua aggcuucagg aggaccauac ggggcaguag     1140

gaguugaucu agcuuuugaa caacuacuuu gucgaauauu cggugaagau uuuauagcaa     1200

cauuuaaaag gcaaagaccu gcugcauggg uagaucuaac uauagcauuc gaggcaagaa     1260

aacgaacagc aggaccacau agagcuggug cuuuaaacau uucauuacca uuuucauuca     1320

uagauuuuua cagaaaacaa agaggacaua auguagaaac agcauuaaga agaaguucag     1380

uaaauuuugu aaaauggucu agucaaggaa ugcuaagaau gucaugcgaa gcuaugaacg     1440

aacuauuuca acccacagua uccgguauaa uacaacauau agaagcacua uuagcuagac     1500

cugaaguaca aggaguaaaa uuauuauuuu uaguaggagg auucgcagaa ucagcugugu     1560

uacaacaugc ugugcaagca gcguugggcg cuagaggucu aagaguagua guuccucacg     1620

auguaggacu aacaauacua aaaggagcag uauuauucgg ccaagcgccu ggaguaguuc     1680

gaguaagaag aucuccauua acauauggug ugggaguauu aaauagauuc gugccaggua     1740

gacauccacc agagaagcua uuaguaagag auggcaggag gugguguacu gaugucuucg     1800

aaagguuugu ugcagccgaa caaagcguug cacuaggaga agaaguuaga agaucauacu     1860

guccagcacg gccaggacaa agaagagugc uaauuaacuu auauuguugc gcagcagaag     1920

augcaagauu uauuacagac ccagguguaa gaaagugugg agcccucagu uuagaacuug     1980

aaccagcuga uugcggccaa gauacagcag gcgcaccccc aggcagacga gaaauaagag     2040

cggcaaugca auuuggagau acagaaauaa aaguuacagc uguagaugua agcacaaaca     2100

gaaguguuag agcaucaaua gacuuucuaa guaacuaagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  6838
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt6)

<400>  6838
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuagagaaa ugacaauacu cggcucugca guauuaaccu      120

uacuauuagc aggauauuua gcacaacaau accuucccuu accaacacca aaaguaauag      180

guauagaucu cgguacaaca uauuguuccg ucggaguuuu cuuuccagga accggaaaag      240

uuaaaguuau accagacgaa aauggacaca uauccauacc aaguauggua aguuuuaccg      300

acaacgaugu auaugucggu uacgaaagcg uagaauuagc agauaguaau ccacaaaaca      360

caauauauga cgcaaaaaga uucauaggaa aaaucuucac cgcagaagaa cuggaagcag      420

aaauaggaag auauccauuc aaaguacuaa auaaaaaugg aaugguagaa uucucaguaa      480

cuuccaauga aacaauaaca guaucaccag aauaugucgg cucaagauua uuauuaaaau      540

uaaaagaaau ggcagaagca uacuuaggaa ugccaguagc aaacgcagua aucucaguac      600

cagccgaauu cgauuuaaaa caaagaaauu ccacuauaga agcagcaaau cuagcagguc      660

uuaaaauauu aagaguaaua aaugaaccca cagcagcagc aauggcauau ggacuacaca      720

aagcagaugu uuuucacgua cuagugauag auuuaggagg cggcacauua gacguaaguc      780

uacucaauaa acaaggcggu auguuucuaa caagagccau gaguggaaac aacaaauuag      840

gaggacaaga cuuuaaccaa agacuacuac aauauuuaua caaacaaauu uaccaaacau      900

auggauucgu cccaucaaga aaagaggaaa uccacagacu aaggcaagca guagagaugg      960

ucaaacuaaa cuuaacauua caucaaucag cacaacuauc agucuuauua acaguagaag     1020

agcaagauag aaaagaaccu cacuccagug acacagaacu cccuaaagau aaacuaucau     1080

cagcagauga ccaccgaguc aacaguggau ucggaagagg ccuaagugac aaaaaaagcg     1140

gagaaucaca aguauuauuu gaaacugaaa uuagcagaaa acuauuugau acauuaaaug     1200

aagaccuauu ucaaaaaaua cuaguaccaa uacaacaagu acucaaagaa ggacauuuag     1260

aaaaaacaga aauagacgaa guaguacuag uaggaggaag cacacgaauu ccuagaauaa     1320

gacaaguaau acaagaauuu uucggcaaag acccuaauac aucaguagac ccagaucuag     1380

ccgucguaac aggaguagca auacaggcag gaauagaugg aggaagcugg ccacuucaag     1440

ucagugccuu agaaauccca aacaaacauu uacaaaaaac caauuucaac uaaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6839
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt6)

<400>  6839
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagcaauag gaguacaccu aggauguaca ucagcaugug      120

uagccguaua uaaagauggu agagcaggag uuguggccaa ugaugccgga gauagaguaa      180

cuccugcagu aguugcauac agcgaaaaug aagagauagu uggacuagcu gcaaaacaaa      240

gcagaauaag aaauauaagu aauacaguaa ugaaagucaa acaaauauua ggaagaucaa      300

guucagaccc ucaagcucaa aaauacauug cugaaagcaa augucuagua auagagaaaa      360

auggaaaacu aagauaugaa auugauacgg gugaagaaac uaaauucgua aacccagaag      420

auguagcaag acuaauauuu aguaaaauga aagaaacagc ucauucagua uuaggaucag      480

acgcaaauga cguaguaaua acuguaccau ucgauuuugg agaaaaacaa aagaacgcuu      540

uaggagaagc ggcuagagca gcagguuuua auguauuaag acuaauacau gaaccauccg      600

cugcacuauu agcauacgga auaggacaag auaguccaac agguaaauca aauauccuag      660

uauucaaauu aggaggaaca ucauuaucgu uaucaguaau ggaaguaaau agugggauau      720

auagaguauu gagcacaaau acagaugaua auauaggcgg agcacauuuu acagaaacuc      780

uagcacaaua ucuagcaagu gaauuucaaa gaaguuuuaa acaugauguu cgaggaaaug      840

caagagcaau gaugaaauua acaaauucag cggaaguagc aaaacacuca uuaagcacgu      900

uagguagugc aaauuguuuc uuagauaguu uauaugaagg acaagauuuu gauuguaaug      960

uaucacgagc ccgauuugaa uuauuaugua gcccucuauu uaauaaaugu auagaagcaa     1020

uaaggggauu acucgaucaa aauggauuca cagcugauga uauaaauaaa guaguauuau     1080

guggagguuc aaguagaaua ccuaaauuac aacaacuaau aaaagacuua uuuccagcag     1140

uagaacugcu aaauaguaua ccgccagacg aaguaauacc aauaggagca gcaauugaag     1200

ccggaauacu aauuggaaaa gaaaaucuau uaguagaaga cagccuuaug auagaaugua     1260

gugcaagaga cauacucguc aaaggcguag augaauccgg agcaaguaga uucacuguau     1320

uauucccauc aggaacgcca cuaccagcaa gaagacaaca uacacuacaa gcaccaggaa     1380

gcauaucaag uguaugucua gaacuauaug aaucagacgg gaaaaauagc gcaaaagaag     1440

aaacaaaauu ugcacaagua guauuacaag auuuagacaa gaaagaaaau ggauuaagag     1500

auauauuagc aguauuaacu augaaacgag acggaagucu acauguaaca uguacagauc     1560

aagagacagg aaaaugugaa gcgauaucaa uagaaauugc uagcuaagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  6840
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt6)

<400>  6840
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaguaguag gacuugaugu aggaucacaa ucauguuaua      120

uagcaguagc acgagcagga gguauagaaa caauagcaaa ugaauucagc gauagaugua      180

caccuucagu cauaucuuuc ggaucaaaga aucgaaccau uggcguagcc gcaaaaaacc      240

aacaaaucac gcacgcuaac aauacaguau caaacuuuaa aagauuucac ggucgagcgu      300

uuaaugaccc cuucauucaa aaagaaaaag aaaacuuaag cuaugaccuu guaccacuua      360

aaaauggagg aguaggcauu aaaguaaugu acaugggaga agaacaccua uuuaguguag      420

aacaaaucac cgcgaugcua cuaacaaaac uaaaagaaac agcagagaau agccuaaaaa      480

aaccaguuac ugacugcgua auaaguguac caucuuucuu uaccgacgca gaaagacggu      540

ccguucuaga ugcagcccaa auaguaggau uaaacugucu cagacuaaug aaugauauga      600

cugcaguggc ucuaaauuau ggaauauaua aacaagacuu gccaucacua gaugaaaaac      660

caagaaucgu agucuucguc gauaugggcc auagcgcauu ucaaguuuca gcaugugcuu      720

ucaacaaagg aaaacugaaa guucuaggaa cggcauucga uccauuucua gggggaaaaa      780

auuuugacga aaaauuagua gaacacuuuu gcgccgaauu caaaacaaaa uacaaacuag      840

acgcaaaaag uaaaauaaga gcauuauuga gauuauacca agaaugcgaa aaacuaaaaa      900

aauuaaugag cuccaacuca acagacuugc cauuaaacau agaaugcuuc augaaugaua      960

aagacguauc cgguaaaaug aauagauccc aguucgagga acuaugugcc gaacuacuuc     1020

aaaaaauaga aguaccauua uacucacuau uagaacaaac ucaccuaaaa gucgaagacg     1080

uaagugcagu agaaauugua gguggagcaa caagaauacc ggcuguaaaa gaaagaauag     1140

caaaauucuu uggaaaagau auaucaacaa cauuaaacgc cgaugaagcc guagcuagag     1200

ggugcgcacu ucaaugcgcc auauuaucac cagcguuuaa agucagagaa uucaguguua     1260

ccgaugcagu accauuccca auaaguuuaa uauggaacca ugacucagaa gacaccgaag     1320

gaguucauga aguauuuagc cgaaaccacg ccgcaccauu uaguaaagua uuaacauuuc     1380

uaagacgugg uccauuugag cuugaagcau uuuauucuga uccacaagga guaccauacc     1440

cagaagcaaa aauaggcaga uuugucguac aaaacguauc ggcacaaaaa gauggagaaa     1500

aaucacgagu caaaguaaag gugagaguaa acacacaugg aauauucaca auaaguacag     1560

ccagcauggu ggaaaaaguu ccaacagaag aaaacgaaau gagcagcgaa gcagauaugg     1620

aaugucuaaa ccaaagaccg ccagaaaacc cagacacaga uaagaauguc caacaagaca     1680

acucugaagc aggcacucaa ccacaaguuc aaacagaugc acaacaaacu ucacaaucac     1740

caccgucucc agaauuaacc agugaagaaa acaaaauacc cgacgcagau aaagcaaacg     1800

aaaaaaaagu agaccaacca ccagaagcaa agaaaccaaa aauuaaaguc gugaacguag     1860

aauuaccaau agaagcaaau cuaguauggc aauuaggcaa agaccuauua aauauguaua     1920

ucgagaccga agguaaaaug auaaugcaag acaaauuaga gaaagaacga aaugaugcaa     1980

aaaaugcagu agaagaauau guauaugaau uuagagauaa acuaugugga ccguacgaaa     2040

aauuuauaug ugaacaagac caucaaaauu uucuacgacu ucuaacugag acagaagacu     2100

ggcuauacga agaaggagaa gaucaagcaa aacaagcgua uguagacaaa cuagaagaau     2160

uaaugaagau agguacacca guaaaaguac gauuccaaga agcagaagag agaccaaaaa     2220

uguuugaaga acugggucaa agauuacaac acuaugcaaa aaucgccgca gacuuucgaa     2280

acaaagacga aaaguauaau cauauagaug aaucagaaau gaaaaaaguc gaaaaaagug     2340

ucaacgaagu gauggagugg augaauaacg uuaugaaugc acaagccaaa aaaagccuag     2400

aucaagaucc uguaguaaga gcacaagaga ucaaaaccaa aauaaaagaa cuaaauaaca     2460

ccugcgagcc agugguuacc cagccaaaac caaaaauaga aagucccaaa uuagagagaa     2520

cccccaaugg accaaauaua gauaaaaaag aagaagaccu agaggauaaa aauaacuucg     2580

gagccgaacc accacaccaa aauggggaau guuaccccaa cgaaaaaaau aguguaaaca     2640

uggauuuaga cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  6841
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt6)

<400>  6841
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcugauaaag ucagacgaca acggccaaga agaaggguau      120

gcugggcacu gguagcaguu cugcuagccg auuuauuagc guuaucagau acccuagcug      180

uaaugagcgu agacuuaggc agugaaagua ugaaaguggc aauaguaaaa ccaggaguac      240

ccauggagau uguuuuaaau aaagaaucaa gaagaaagac gccaguaaua guaacgcuaa      300

aagagaacga aagauucuuu ggagacucag cagcaaguau ggcaauuaaa aacccaaaag      360

caacccugag auacuuucaa caucuguugg gcaaacaagc agacaaccca cauguagcgc      420

uauaccaagc gagguuuccu gaacacgaac uaacauucga cccacaaaga caaacaguac      480

acuuccaaau aucuucacaa cuccaauuuu caccugagga aguacuugga auggucuuaa      540

acuacagucg aaguuuggcg gaagauuuug ccgaacaacc uauaaaagau gcaguaauaa      600

caguaccugu auucuuuaau caagccgaga ggagagcugu auuacaagcu gcaagaaugg      660

cuggacuuaa aguacuacaa cucauaaaug acaauacagc uacugcacua ucauauggug      720

uuuuuagaag aaaagacaua aacacaacug cacaaaauau cauguuuuac gauaugggaa      780

gcggaagcac agucugcacu auagucaccu aucagauggu gaaaacaaaa gaagcaggaa      840

ugcagccuca auuacaaaua agaggaguag guuuugacag aacgcugggu ggauuagaaa      900

uggaacugag auuaagagaa cgauuggcag gacuauucaa ugagcaacga aagggucaga      960

gagcuaaaga cguuagagaa aauccucgcg caauggcuaa acuuuuacgc gaagcaaaua     1020

gauuaaagac aguacuuagu gcaaacgcag accauauggc ucaaauagaa ggacuaaugg     1080

augacguaga cuuuaaagca aaaguaacac gaguagaguu cgaagaacua ugugcagauc     1140

ucuuugaaag aguaccuggu ccaguacaac aagcucuaca aagugcugaa augucuuuag     1200

acgaaauuga acaaguaaua uuggucggcg gagcaacacg aguuccuaga guacaagaag     1260

uauugcuuaa ggcaguagga aaagaagaac uagggaaaaa uauaaacgcu gacgaagcag     1320

cagcaauggg agccguuuac caagcggcag cacuaagcaa ggcuuuuaaa guuaaaccau     1380

uuguaguaag agaugcaguu guauauccaa uuuuaguaga auuuacucga gaaguagaag     1440

aagaaccagg gauacacuca cuaaaacaca acaaaagagu acucuuuagc aggaugggac     1500

cguauccaca acguaaaguc auaacauuua acagauauuc ucaugauuuu aauuuccaua     1560

uaaacuacgg agacuuaggc uuuuuagguc cagaagaucu aaggguauuu gguucacaaa     1620

aucucacaac gguuaaacua aaagggguag gagauaguuu caagaaauac ccagacuaug     1680

aaucuaaagg aauaaaagca cauuuuaauc uagaugaaag ugggguauug agucuagacc     1740

gagucgagag cguauucgaa acucugguug aagauagugc cgaagaggaa ucaaccuuga     1800

cuaaacuagg uaauacgaua agcagcuuau ucggaggugg cacaacacca gaugcaaaag     1860

aaaauggaac agacacagua caggaagaag aagaaagccc ggcagagggc ucaaaagaug     1920

aaccugggga acaaguagag uuaaaagaag aagcagaagc accaguggaa gacgguucgc     1980

aaccaccucc cccagagcca aaaggugaug caacaccaga aggcgaaaaa gcaacagaaa     2040

aagaaaaugg ggauaaauca gaagcacaaa agccaaguga aaaagcagaa gcuggaccag     2100

aaggaguugc uccugcacca gaaggagaaa agaaacaaaa acccgcacgc aaaagaagaa     2160

ugguagagga aauagguguc gagcuaguag uauuagaucu accagaucuc ccagaagaca     2220

aauuggcaca aaguguacaa aaacugcagg acuuaaccuu aagagacuua gaaaaacaag     2280

aaagggaaaa agcugcaaau ucuuuggaag cauucauauu cgaaacacag gacaaauuau     2340

aucaacccga auaucaggaa guauccacag aagaacaaag agaagaaaua ucaggaaaac     2400

ucucagcagc aucaacgugg uuggaagaug aaggaguagg ugcaacaaca guaauguuaa     2460

aagaaaaauu agcagaacua aggaaacugu gccaaggauu auuuuucaga gucgaagaaa     2520

gaaagaaaug gccagaacgg uuaucugcau uagauaauuu acuaaaccac ucuaguaugu     2580

uucuaaaagg ggccagauua auaccagaaa uggaucaaau uuuuacugaa guagaaauga     2640

caacacuaga aaaaguaauc aacgaaacau gggcauggaa aaaugcaacu uuagcagaac     2700

aagcaaaauu accggcaaca gaaaaaccag ucuuacuauc aaaagacaua gaagcgaaaa     2760

ugauggcauu agacagagaa guccaauacc uacuaaacaa agcaaaguuc acaaaaccca     2820

gaccgcggcc aaaagauaaa aacggaaccc gagccgagcc accacuaaau gcaagcgcaa     2880

gugaucaagg ggagaaggua auaccgccug caggacaaac agaagacgca gaaccaaucu     2940

ccgaaccaga aaaaguagaa acaggaucgg aaccuggaga uacagaaccc cuagaauuag     3000

gaggaccugg agcugagcca gaacaaaaag aacaaaguac aggacaaaaa cgaccucuua     3060

aaaaugacga acuauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6842
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt6)

<400>  6842
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaagaaa cccaaacaca agaccaaccc auggaagaag      120

aggaaguaga aacauucgcu uuccaagcag aaauugcaca auuaaugagu cuaauuauaa      180

acacauucua cucaaacaaa gaaauauuuu uacgcgaacu aauaagcaac ucaagcgaug      240

cauuagauaa aauuagauau gaaucguuaa cagauccaag caaauuagac ucaggaaaag      300

aauuacacau aaaucuuauc ccaaacaaac aagauagaac acuuaccaua gucgacaccg      360

gaauaggaau gacaaaagcu gaccuaauaa acaauuuagg uacaauagca aaaucgggua      420

ccaaagcauu cauggaagca cuacaagcag gugccgacau cucgaugaua ggacaauuug      480

gaguaggauu cuacagcgca uaccuaguag cagagaaagu aacaguuaua acaaagcaca      540

acgacgacga acaauacgcc ugggaaucaa gugcaggagg aucauucaca guaagaacag      600

acacagguga accaaugggc agagguacga aaguaauacu ucaucuuaaa gaagaccaaa      660

cagaauaccu agaggaaaga agaaucaaag aaauaguaaa aaaacacuca caauucauag      720

gauauccaau aacacucuuu guagagaaag aaagagacaa agaagucagu gacgaugaag      780

cagaggaaaa agaagauaaa gaagaagaaa aagaaaaaga agaaaaagaa agugaagaca      840

aaccagaaau agaagacgua ggaucggaug aggaggaaga aaaaaaagau ggagacaaaa      900

aaaaaaagaa aaaaauaaaa gaaaaauaca uagaucaaga agaacugaac aaaaccaaac      960

caauauggac aaggaacccc gacgacauca caaacgaaga auacggagaa uuuuacaaau     1020

cacuuacaaa ugacugggaa gaccaccucg ccgucaaaca cuuuagcgua gaaggucaau     1080

uagaauucag agcccuacug uuuguaccua gaagagcacc auucgauuug uuugagaaua     1140

gaaaaaaaaa aaauaauauc aaacuauacg uaagaagagu auuuauaaug gacaauugcg     1200

aagaauuaau accagaauau cuaaauuuua ucaggggagu agucgacagc gaagauuuac     1260

cauuaaacau aucgcgagag auguuacaac aaucaaaaau ucugaaagua auaagaaaaa     1320

aucuagucaa aaaaugucua gaacuauuca cagaacuagc agaagacaaa gaaaacuaca     1380

aaaaauucua ugaacaauuc ucaaaaaaua uaaaauuggg cauacacgaa gacucucaga     1440

auagaaaaaa acuaucagaa uuacuaagau auuauacguc agcuagugga gacgagaugg     1500

uaucccuaaa agacuacugc acaaggauga aagaaaauca aaaacauaua uacuacauaa     1560

cuggagaaac caaggaccaa gucgcaaacu cagcauucgu agaaagauua cgaaagcaug     1620

gacuggaagu aauauacaug auagaaccca uagaugaaua uugcguacaa caauuaaaag     1680

aauucgaagg aaaaacuuua guaagcguaa cgaaagaagg acuagaauua cccgaagaug     1740

aagaagagaa aaaaaaacaa gaagagaaaa aaaccaaauu cgaaaacuua uguaaaauaa     1800

ugaaagacau auuagaaaaa aaaguagaaa aaguuguagu aucaaacaga cuaguaacaa     1860

gcccauguug cauaguaaca aguaccuacg gguggacggc aaacauggaa agaauaauga     1920

aagcccaagc uuuacgagac aauaguacga ugggauacau ggcagccaaa aagcauuuag     1980

aaauaaaccc agaccacagc auaaucgaaa cacuuagaca aaaagccgaa gcugauaaaa     2040

acgacaaauc cgugaaagac cucgucaucu uacuuuauga aacagcauua uuaaguagug     2100

gauucucccu agaagacccg caaacacacg cuaaucgaau auaccgaaug auuaagcucg     2160

gauuaggaau agacgaagau gacccaacag cggaugauac aagcgcagca guaacugaag     2220

agaugccacc auuagaagga gaugaugaua cgucaaggau ggaagaaguc gacuaaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  6843
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt6)

<400>  6843
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucaagca aacuagacag cggaaaagga cuacacauaa      120

acuuaguacc aaacaaacaa aaccaaacac uaacaauagu agacacaaga auaggaauga      180

caaaaacaga cuuaauaaac aaccuaggaa caguaacaaa aucaggaaca aaagcauuca      240

uggaagcacu acaagcagac gcagacauau caaugauagg acacuucgga guaggauucu      300

acucagcaua ccuaguagca aaaaaaguaa caguaauauc aaaacacaac aacgacgaac      360

aauacacaug ggaaucauca gcaggaggau cauucacagu aagaacagac gaauaaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  6844
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt6)

<400>  6844
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaagaag ugcaucaugg cgaagaggag guagaaacau      120

ucgcuuuuca agcugaaaua gcucagcuaa ugagccuaau aauaaacacu uuuuacagca      180

acaaagaaau auuucuccgc gaguuaauau caaacgcuuc agaugcacuu gauaaaauaa      240

gauacgagag ccuaacagac ccuaguaaac uagauagcgg uaaagaacua aaaauagaca      300

uaauacccaa cccgcaagaa agaacacuua cacuugucga uacuggaaua ggaaugacaa      360

aagcagaucu aauaaauaac uuaggaacaa uagcaaaauc agggacgaaa gcguuuaugg      420

aagcauuaca agcaggagca gauauuagua ugauaggaca auuuggagua ggauucuaca      480

gugcuuaucu uguagcagaa aaaguaguag uaauaacaaa acacaaugac gacgaacaau      540

augcuuggga aucuucagcc ggagggucau ucacgguuag agcagaccac ggagaaccaa      600

uaggaagagg cacuaaggua auacuacauu uaaaggaaga ucagacagaa uaccuugaag      660

aacgaagagu aaaagaagua guaaaaaaac auucacaauu uauaggauac cccauaacau      720

uauaccugga aaaagaaaga gaaaaagaaa uaucugacga cgaagccgaa gaagaaaaag      780

gagaaaaaga agaagaagac aaagaugaug aagaaaaacc gaaaaucgaa gacguaggau      840

cagacgaaga agacgacuca ggaaaagaca aaaaaaaaaa aacaaaaaaa auaaaagaaa      900

aauacauaga ucaagaagaa uugaacaaaa caaaaccaau auggacaaga aauccagaug      960

auauaacaca agaagaauau ggagaauucu acaaaagucu uacaaaugac ugggaagacc     1020

aucuagcagu caaacauuuu ucaguagaag gacaacuaga auucagagcg uuauuauuua     1080

uaccaagaag agcgccauuc gaccuauuug aaaacaaaaa aaaaaaaaac aauauaaaac     1140

uauacguaag aagagucuuc auaauggacu cgugcgauga auuaauacca gaauacuuaa     1200

auuucauaag aggaguaguc gauuccgaag acuuaccacu aaauauaucu cgagaaaugu     1260

uacaacaauc caaaauacua aaagugauaa gaaaaaauau cguaaaaaaa ugucuugaac     1320

uauuuucgga acuugcggaa gacaaggaaa auuauaaaaa auuuuaugaa gcguucagua     1380

aaaacuuaaa gcuaggcaua caugaagacu ccacaaauag aagaagacua agcgaacuau     1440

uaagauacca uacaucacaa ucaggagacg aaaugacauc ucuaagugaa uaugugagca     1500

ggaugaaaga aacccaaaaa ucaauauacu acauaacagg agaaucgaaa gaacagguag     1560

caaauucagc auucgucgaa cguguacgca aaagaggauu ugaaguagua uacaugacug     1620

agccaauaga cgaauauugu guacaacaac uaaaagaauu cgacggaaaa agucuaguca     1680

guguaacaaa agaaggacua gaacuaccag aagaugaaga agaaaaaaaa aaaauggaag     1740

aaagcaaagc aaaguucgaa aauuuaugca aauuaaugaa agaaauacua gauaaaaaag     1800

ucgaaaaagu uacaauuuca aauagacuag ucucaucacc augcugcaua gucacaagca     1860

cauacggaug gaccgccaau auggaaagaa uaaugaaggc acaagcauua agagauaaca     1920

gcacgauggg auacaugaug gcaaaaaaac aucuugaaau aaauccagac cacccaauag     1980

ucgaaacacu aagacagaaa gcagaagcag auaaaaacga caaagcugua aaagaccucg     2040

ugguccugcu cuucgaaaca gcauuacuga guucaggauu cucgcuggaa gacccacaga     2100

cucauucaaa uagaauuuac agaaugauaa aacuaggauu aggaaucgau gaagacgaag     2160

uggcagcaga agaaccaaac gccgcggucc cagacgaaau accuccauua gaaggagacg     2220

aggaugcaag ccgaauggaa gaaguagauu aaggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  6845
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt6)

<400>  6845
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgagcuuuau ggguacuagg cuuauguugc guauuacuua      120

cauucggauc aguacgugca gacgaugaag uagauguaga ugguacagua gaagaagauu      180

uaggcaaauc aagagaagga aguaggacag acgaugaggu aguacaaaga gaagaagaag      240

caauucaacu agacggacuu aacgcaucuc aaauaagaga auuacgagaa aaaucagaaa      300

aauuugcauu ccaggcagaa guaaauagaa ugaugaaacu aaucauaaau agucucuaua      360

aaaacaaaga aauauucuua cgagaacuaa uaucaaaugc aagugaugcu uuagacaaaa      420

uacgacuuau cagucuaaca gaugaaaaug cacucagugg caaugaagaa cuaacaguua      480

aaauaaaaug cgauaaagag aaaaauuuac uacauguuac agacaccggu guaggaauga      540

caagagaaga auuaguuaaa aauuuaggaa caauagcaaa aaguggaaca agugaauuuc      600

uaaauaaaau gacugaagcu caggaagaug gacaaagcac uucagaacua auuggacaau      660

ucggaguagg auucuacuca gcauuccuug uagcugauaa aguaaucgua acuagcaaac      720

acaauaacga cacacaacau auaugggaau cagauucaaa cgaauuuagc guaauugcag      780

auccaagagg aaauacacua ggaagaggga ccacaauaac auuaguacua aaagaggaag      840

caagcgacua cuuagaacuc gauacgauua aaaauuuagu aaagaaauac ucacaguuua      900

uaaauuuccc aauauacguc uggaguagua aaacagaaac aguagaagaa ccaauggagg      960

aagaagaagc agccaaagaa gaaaaagaag aaucggacga cgaagcugcu gucgaagaag     1020

aagaagaaga aaagaaacca aaaacaaaga aaguagagaa aacuguuugg gauugggaau     1080

uaaugaacga uaucaaacca auauggcaaa gacccucaaa agaagucgaa gaagacgaau     1140

auaaagccuu uuacaaguca uuuuccaaag aaucggauga cccaauggca uauauucacu     1200

uuacagcaga gggagaaguc acauuuaaau cuauacuuuu ugucccaaca agugcaccga     1260

gaggauuauu ugaugaauac gguucaaaga aaucagacua uauaaaauua uauguaagaa     1320

gaguguucau aacagacgac uuucacgaua ugaugccgaa auacuuaaac uuuguuaaag     1380

gagucguuga cagcgaugac cuaccacuca acguaaguag agaaacacua caacaacaua     1440

aacuauugaa aguuauaaga aagaaacucg uaagaaaaac uuuagacaug auuaagaaaa     1500

uagcagacga caaauauaac gauacauuuu ggaaagaguu cgguacaaau auaaaacuag     1560

gaguaauaga agaccacagu aauagaaccc gauuagccaa auuacucagg uuccaaucau     1620

cgcaucaccc aacagacauc acgagcuuag aucaauaugu agaaagaaug aaagaaaaac     1680

aagauaaaau auacuuuaug gcgggaucau caagaaaaga agccgaaucu ucuccauucg     1740

uugaacgacu auuaaagaaa ggauaugaag uaauauaccu aacagaaccu guagaugaau     1800

auuguauaca agcacuacca gaauuugaug gcaaacgcuu ccaaaaugua gcaaaagaag     1860

gcguuaaauu ugaugaaagc gaaaagacaa aagaaaguag agaagcgguu gaaaaagagu     1920

ucgaaccauu auuaaauugg augaaagaca aagcacuaaa agauaaaaua gaaaaagcug     1980

uaguaucuca aagauuaacc gaauccccgu gcgcacucgu agccagucaa uauggcuggu     2040

cagguaacau ggaaagaaua augaaagcuc aagcauauca aacaggaaaa gauauaagua     2100

cgaacuauua cgcaucucaa aagaaaacau ucgaaauaaa uccaagacac ccacugauaa     2160

gagauauguu aaggcgaaua aaagaagaug aagacgacaa aacaguucua gacuuagcug     2220

ucguacuauu cgaaacagca acauuaagaa gcggauacuu acuaccagac acaaaagcau     2280

auggagauag gauagaacgg auguuacgac uaagucucaa cauagaucca gaugccaaag     2340

uugaagaaga accagaagag gaaccagaag agaccgcaga agacacaaca gaagacacag     2400

aacaggacga agacgaagaa auggacguag gaacugacga agaagaagaa acagcaaaag     2460

aaucuacagc agaaaaagac gagcuguaag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  6846
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt6)

<400>  6846
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacgagaau uaagagcucu uuuacuaugg gguagacgac      120

ugagaccauu auuaagggcg ccagcccucg cagcaguacc aggaggaaaa ccaauacucu      180

gcccaagaag aacaaccgca caauuaggcc caagaagaaa uccagcaugg ucauuacaag      240

cuggaagacu auuuuccacc caaacagcag aagauaaaga agaacccuua cauucaauaa      300

uaucaagcac agaaucaguc caaggaucaa caucaaaaca ugaauuucaa gcagaaacaa      360

agaaacuauu agauauuguu gcuagaagcc uuuauucuga aaaagaagua uuuauaagag      420

aacuaauuag uaacgcuagc gacgccuuag aaaagcuaag acacaaguua guaagugaug      480

gacaagcauu accagaaaug gaaauacacc ugcaaaccaa ugcagaaaaa ggaacaauaa      540

ccauacaaga uaccggcaua ggaaugacac aagaagaauu aguaaguaac cuuggaacaa      600

uagcuagaag cggaucaaaa gcauuccucg acgcacuaca aaaccaagca gaagcaucau      660

ccaaaauaau uggacaauuu ggcguaggau ucuauagugc cuuuauggua gcagaucgug      720

ucgaagucua uucacgauca gcagcaccag gaucacuagg guaucaaugg uuaucagacg      780

gauccggugu auucgaaauu gccgaagccu cgggcguaag aacggguacu aaaauaauaa      840

uacauuuaaa aucagauugc aaagaauucu cuucagaagc acgaguccga gauguaguaa      900

cgaaauauuc aaacuuuguu aguuuucccu uauauuuaaa uggucguaga augaauaccu      960

uacaagcaau auggaugaug gauccaaaag auguuagaga auggcaacau gaagaauuuu     1020

auagauaugu ugcucaagcu caugacaaac cccgauauac uuuacacuac aaaacagacg     1080

caccauuaaa uaucaggagu auauuuuaug ugccagauau gaaacccucg auguuugaug     1140

ucaguagaga auuaggaagc aguguggcuc uauauucuag aaaaguacuc auacaaacca     1200

aagcaacgga uauauuacca aaauggcuca gauuuauaag aggaguuguu gauucagaag     1260

acauacccuu aaaucuuagu agagaacuac uucaagaauc agcauuaaua agaaaauuaa     1320

gagacguccu ucaacaaaga uuaauuaaau ucuuuauaga ccaaucaaaa aaagaugcag     1380

aaaaauaugc aaaauucuuc gaagacuaug gauuauuuau gagagaagga auaguaacag     1440

caacagaaca agaaguaaaa gaggauauag caaaauuauu acgguacgaa ucaucagcau     1500

uaccaucagg acaacuuaca ucauuauccg aauacgccag ucgaaugaga gcaggcacaa     1560

gaaacauaua uuaccuaugu gcaccaaaca gacaucuagc agagcacuca ccuuauuacg     1620

aagcaaugaa aaaaaaagau acagaaguuc uauuuugcuu ugaacaauuu gacgagcuua     1680

ccuuacucca ucuaagagaa uuugacaaaa aaaaauuaau aaguguugaa acagacauag     1740

uaguugauca uuauaaagaa gaaaaauuug aagaucgaag cccagcagca gaaugccuau     1800

cagaaaaaga aaccgaagaa uuaauggccu ggaugcguaa uguucuagga agcagaguua     1860

caaacguaaa aguaacgcua agauuagaua cucauccagc caugguaacu gugcuagaaa     1920

ugggcgcagc caggcacuuc cuaagaaugc aacaauuagc aaaaacacaa gaagaaagag     1980

cacaauuacu ucaaccaaca cuugagauaa aucccagaca ugcauuaauc aaaaaacuaa     2040

accaacuucg ugcaagcgaa ccaggauuag cacaacuuuu aguugaucaa auauaugaaa     2100

acgcaaugau agcagcugga cucgucgaug auccaagagc aaugguggga cgccuuaaug     2160

aauuauuggu aaaagcauug gaacgacauu aaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  6847
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt6)

<400>  6847
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaauau caucacuacc aacacaacua uucaaaugcu      120

gcuucugcga cuuccuaaaa guaaaaaugc acacaauguc aucaucacac cuauucuacc      180

uagcacuaug ccuacuaaca uucacaucau cagcaacagc aggaccagaa acacuaugcg      240

gcgcagaacu aguagacgca uuacaauucg uaugcggaga cagaggauuc uacuucaaca      300

aaccaacagg auacggauca ucaucaagaa gagcaccaca aacaggcaua guagacgaau      360

gcugcuuccg aucaugcgac cuaagaagac uagaaaugua cugcgcacca cuaaaaccag      420

caaaaucagc aagaucagua agagcacaaa gacacacaga caugcccaaa acacaaaaag      480

aaguacaccu aaaaaacgca uccagaggau cagcaggaaa caaaaacuac agaauguaag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  6848
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt6)

<400>  6848
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaauaccaa ugggaaaauc aaugcuagua cuauuaacau      120

uucuagcauu ugcaagcugu ugcauugcag cauacagacc aucagaaaca cuauguggag      180

gagaauuagu agauacauua caauuuguau guggagauag aggauucuau uucucaagac      240

cagcaucaag aguuagcaga agaaguagag gaauaguaga agaaugcugu uucagaagcu      300

gugauuuagc auuacuagaa acauauugcg caacaccagc aaaaagugaa agagauguau      360

caacaccacc aacuguauua ccagauaacu uuccaagaua cccaguagga aaauucuuuc      420

aauacgauac auggaaacaa agcacacaaa gacuaagaag aggacuacca gcauuauuaa      480

gagcaagaag aggacacguu cuagcaaaag aacuagaagc auuuagagaa gcaaaaagac      540

auagaccacu aauagcauua ccaacacaag auccagcaca cggaggagca ccaccagaaa      600

uggcaucaaa cagaaaauaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  6849
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt6)

<400>  6849
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aauuccuucu caacaucagc cuucggacca guagccuucu      120

cacuaggacu acuacuagua cuacccgcag cauucccagc accaguccca ccaggagaag      180

acucaaaaga cguagcagca ccacacagac aaccauuaac aucaucagaa cgaauagaca      240

aacaaauaag auacauauua gacggaauau cagcacuaag aaaagaaaca ugcaacaaau      300

caaacaugug cgaaucauca aaagaagccc uagcagaaaa caaccuuaau cuaccaaaaa      360

uggcagaaaa agacggaugc uuccaaucag gauucaacga agaaacaugc cuaguaaaaa      420

uaauaacagg acuacuagaa uucgaaguau accucgaaua ccuacaaaac agauucgaau      480

ccucagaaga acaagcccga gcaguccaaa ugucaacaaa aguacuaaua caauucuuac      540

aaaaaaaagc aaaaaaucua gacgcaauaa caacaccaga cccaacaaca aacgccuccu      600

uacuaacaaa acuacaagca caaaaccaau gguuacaaga caugacaaca caccucauac      660

uaagaucauu caaagaauuc cuacaauccu cacuaagagc acuuagacaa auguaaggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  6850
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt6)

<400>  6850
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuacugu gguuaagagg uuuccuauua gcaagcugcu      120

ggauaauagu aagaagcagu ccaacaccag ggagcgaagg acacagugcg gcaccagacu      180

gcccaucaug ugcgcuagca gcauuaccaa aagacguucc aaauagucaa ccagaaaugg      240

uugaagcagu aaaaaaacau auauuaaaua ugcuacaucu aaaaaaaaga ccagauguaa      300

cacaaccagu accgaaagca gcauuauuaa augcaauacg aaaauuacau gucggaaaag      360

uaggagaaaa cggauaugua gaaauagaag acgacauugg aagaagagca gaaaugaacg      420

aauuaaugga acaaacaagu gaaauuauaa cguuugcaga aucaggaaca gccagaaaaa      480

cacuacacuu ugaaauauca aaagaaggcu cagaccuauc aguuguagaa agagcggaag      540

uaugguuauu ucuaaaagua ccuaaagcaa acagaacaag aacaaaagua acaauuagac      600

uauuucaaca acaaaaacac ccacaaggaa gucuagauac aggagaagaa gcagaagaag      660

uaggauuaaa aggagaaagg agugaauuac uauuaaguga aaaaguagua gacgcaagaa      720

aaucaacaug gcacguauuu ccaguaucau caagcauaca acgacuacua gaccaaggaa      780

aauccucauu agauguaaga aucgcaugcg aacaauguca agaaaguggu gcaucauuag      840

uacuauuagg aaaaaaaaaa aaaaaagaag aagaaggaga aggaaaaaaa aaaggaggag      900

gagaaggagg ugcaggagca gacgaagaaa aagaacaaag ccauagacca uucuuaaugu      960

uacaagcaag acaaagugaa gaccauccuc auaggagaag aagaagagga cuugaaugcg     1020

acggaaaagu aaauauaugu uguaaaaaac aauucuuugu aagcuuuaaa gauauaggau     1080

ggaacgauug gauaauagcu ccaaguggau aucacgcaaa uuacugcgaa ggagaaugcc     1140

caucacacau agcgggaaca agcggaagcu cacuaucauu ccauagcaca guaauaaacc     1200

auuacagaau gagaggacau aguccauucg caaacuuaaa aucaugcugu gucccaacaa     1260

aacuaagacc aauguccaug uuauauuaug augacgguca aaauauaaua aaaaaagaua     1320

uacaaaacau gauaguagaa gaauguggcu guagcuaagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  6851
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt6)

<400>  6851
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gauggauuac ccgggagggc acuaggugca gcuugccuau      120

uacuacuagc agcaggaugg cuaggaccag aagcaugggg aagcccgaca ccaccuccua      180

caccagcagc accaccacca ccuccuccac caggaucacc aggaggaagu caagacacau      240

guacaucaug cggaggauuc cgaagaccag aagaacuagg aagaguagau ggagauuuuc      300

uagaagcagu uaaacgacau auacuaucua gacuacaaau gcgaggaaga ccaaauauaa      360

cacacgcagu uccaaaagca gcaaugguaa cagcacuuag aaaauuacau gcagguaaag      420

uacgugaaga uggaagagua gaaauaccac aucuagacgg ucacgcuuca ccaggagcug      480

acggucaaga aagaguauca gaaaucauca gcuuugccga aacugaugga cuagcaucau      540

cacgaguuag auuauauuuu uuuauuagua augaaggaaa ucaaaauuua uucguugucc      600

aagcuucauu auggcuuuau uuaaaauuac uaccuuaugu auuagaaaaa ggaucaagaa      660

gaaaaguaag aguuaaaguc uauuuccaag aacaagguca uggagauaga uggaauaugg      720

uagaaaaaag aguagaccua aaaagaucag gauggcacac uuucccauua acagaagcaa      780

uacaagcauu auucgaaaga ggagaaagaa gacuaaauuu agacguucaa ugugacucau      840

gucaagaauu agcaguagua ccaguuuuug ucgauccagg agaagaaagu cauagaccuu      900

uuguaguagu acaagcgaga uuaggagauu caagacacag aauaaggaaa agaggauuag      960

aaugugacgg gagaacaaac uuauguugua gacaacaauu uuuuauagau uuucgacuaa     1020

uaggauggaa ugauuggaua auagcaccua caggauauua uggaaauuau ugugaaggaa     1080

guuguccagc auauuuagca ggaguaccag gaucagcaag caguuuucau acagcaguag     1140

uuaaucaaua uagaaugaga ggacuaaauc cuggaacggu aaauucgugu ugcauuccua     1200

caaaacuauc aacaaugagc auguuauacu ucgaugacga auauaauaua guuaaaagag     1260

acguaccaaa caugauugua gaagaaugug gaugugcuug aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  6852
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt6)

<400>  6852
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucucagag uacuacuacu aacugcacua acuuuaugcc      120

acggcuucaa cuuagauacc gaaaacgcca ugacuuuuca agaaaaugca agagguuucg      180

gacaaucugu aguacaacua caaggcucaa ggguaguugu aggcgccccu caagaaaucg      240

uagccgcuaa ucagcgaggu ucucuuuauc aaugugauua uucaacugga uccugugaac      300

ccauccgauu acaaguaccu guagaagcug uaaauauguc acuuggacua agucucgcug      360

caacaacauc acccccgcaa cuacucgcau guggcccaac cguacaucag acauguucug      420

aaaacacaua cguaaaagga uuauguuucc uauuuggcag uaacuuacga caacaaccac      480

aaaaauuccc agaagccuua agaggauguc cucaagaaga uagcgauauu gcauuccuca      540

uagauggauc ugguuccauu auaccucaug auuuccggcg aaugaaagaa uuuguuucaa      600

cagucaugga acaacuaaag aaaucaaaaa cauuauuuuc cuuaaugcaa uauagugaag      660

aguuccgaau acauuuuacc uucaaagaau uucaaaauaa cccaaacccg cgaagucucg      720

uaaaacccau uacccaacuu cuagguagaa cucacacagc aacagguauu agaaaaguug      780

uucgagaguu auuuaauauu acaaacggag cacguaaaaa cgcuuucaaa auccuaguug      840

uaauaacaga cggagaaaaa uuuggugacc cacuagguua ugaagauguu aucccagagg      900

cugacagaga aggagucauu agauauguca uaggaguagg agaugcauuc cgcagugaga      960

aaaguagaca ggaacuuaac acgauagccu cuaaaccccc aagggaucac gucuuccaag     1020

uaaacaacuu ugaggcuuua aaaaccauac aaaaccaauu gcgugagaaa auuuuugcua     1080

uagaagggac acaaacugga uccucaucuu cauuugaaca ugaaaugucu caagaaggau     1140

uuucagcagc caucacauca aacggaccuu uacuaucaac cguuggcucc uaugauuggg     1200

cuggaggagu cuuccuuuau acuucuaaag aaaaauccac uuuuauaaau augacccggg     1260

uugauagcga caugaaugac gccuauuugg guuaugcagc ugcuauaaua cuacgaaauc     1320

guguccaaag uuuaguccua ggagcuccca gauaucagca uauugguuua guugcgaugu     1380

uuagacaaaa cacagguaug ugggaaucaa augcaaaugu uaaaggaaca caaauugggg     1440

cauauuucgg cgcuucccua uguucaguag acgucgauuc aaauggaucc acggauuuag     1500

uucucauagg ugcaccacac uauuaugaac aaacccgagg uggccaaguc uccguaugcc     1560

cccuaccacg cggccgugca cguuggcagu gcgacgcugu acuuuauggu gaacaaggac     1620

aaccuugggg acguuuugga gcagcccuaa cuguacuugg agacguuaau ggcgacaaau     1680

uaacggaugu ugcgaucggg gcaccaggcg aagaagauaa uagaggagcc guauacuuau     1740

uucauggcac aagcggcuca ggaauaucac cuucacauag ucaaagaaua gcaggaucaa     1800

aacuaucucc aagauuacaa uacuuugggc aaagucuaag cggcggacaa gaccuuacaa     1860

uggauggauu aguagaucua accguuggag cacaaggaca uguauuauua uuaagauccc     1920

aaccuguucu uagagucaaa gcuauuaugg aauuuaaccc uagagaagua gcucgcaaug     1980

uuuuugaaug uaaugaucag guuguuaaag guaaagaagc aggagaaguc cguguuuguc     2040

uucacguaca gaaaucaacu agggauagac uaagagaagg acaaauacaa aguguuguua     2100

cauaugauuu agcacuagac ucuggucgac cacauucaag agcaguuuuc aacgagacua     2160

aaaacucaac acgaagacaa acccagguau uagguuuaac acaaacuugc gaaacacuua     2220

aacuacaauu accuaauugc auagaagauc caguuucacc aauaguccua cgauuaaacu     2280

ucucauuagu uggcacccca cuguccgcuu ucggaaaccu acgucccguc cucgcagaag     2340

acgcacaaag acuauuuaca gcuuuauucc cuuuugaaaa gaauugcggc aaugauaaua     2400

uaugucaaga cgaucuuuca auuacuuuua guuuuauguc acuagauugc cuaguaguag     2460

gaggaccaag agaauuuaau guaacaguua caguacgcaa cgacggagaa gacucuuauc     2520

gaacacaagu uacauuuuuc uuuccauuag acuuaaguua ccgaaaagua ucaacccuuc     2580

aaaaucaacg aucacaaaga ucauggaggu uagccugcga aucggcauca uccacugaag     2640

uaucuggugc acucaaaagu acuucauguu ccauuaauca uccuauauuu ccugaaaauu     2700

ccgaaguaac cuuuaacaua acauuugaug uugauucaaa agccucucuc gguaauaaau     2760

uacuacuuaa agcaaacgug acauccgaaa auaacaugcc aagaacuaau aaaacggaau     2820

uucaauuaga auuaccuguu aaguacgcag ucuacauggu ugugacaagu cauggcguuu     2880

ccacaaaaua ucuuaacuuu acagcaagug aaaacacauc aaggguuaug caacaucaau     2940

aucaagucag uaaccuuggu caacgaagcc uaccaaucuc auuggucuuu cucgucccag     3000

uaagacuaaa ucaaaccgua auaugggauc gaccgcaagu uacuuucagu gaaaacuuaa     3060

guucuacaug ccacacaaaa gaaagacuuc caucucacuc ugacuuucua gcugaacuac     3120

gaaaagcucc cguuguaaac uguucuauag caguuuguca acguauacaa ugugauauuc     3180

cauucuuugg aauacaagaa gaguucaaug cuacauuaaa agguaauuua ucguuugauu     3240

gguacauuaa aacuagccau aaucauuuau uaauaguuuc uacugcagaa auccuguuua     3300

augauuccgu auucacucua uuacccggac aaggagcauu uguaagaucc caaaccgaaa     3360

caaaaguaga accuuuugaa guccccaacc cucuuccuuu aaucguugga ucaagcguug     3420

gcggacuauu acuuuuagcc uuaauaacgg cggcauuaua uaaauuagga uucuucaaac     3480

gccaauauaa agauaugaug ucugaaggug gaccuccugg agcagaacca caauaaggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  6853
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt6)

<400>  6853
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuuucacuaa aaacauuacc uuuccuacuu cuacuacacg      120

uacaaauauc aaaagcauuu ccagucucau caaaagaaaa aaacacaaaa acaguacaag      180

auuaucucga aaaauuuuac caauuaccau caaaucaaua ucaaucaaca cgaaaaaaug      240

gaacaaacgu aauaguugaa aaauuaaaag aaaugcaaag auucuuugga cucaauguca      300

caggcaaacc uaacgaagaa acacuagaca ugaugaaaaa accaagaugc ggaguaccag      360

acucaggagg auucauguua accccaggca acccuaaaug ggaaagaaca aaucuaacau      420

acagaauacg aaacuauaca ccacaacuau ccgaagcaga agucgaaaga gcaauaaaag      480

acgcuuuuga acuuugguca guagccuccc cacuaauauu cacacgaaua ucacaaggag      540

aagccgacau caacauagca uuuuaucaac gagaccacgg agacaauucc cccuucgacg      600

gaccaaaugg aauacuagca cacgcauucc aaccuggaca aggaauagga ggagaugcac      660

auuucgacgc agaagaaaca uggacaaaca caucagcaaa cuacaaccua uucuuagucg      720

cagcacacga auucggacau ucucuaggac uagcccauuc aucugacccc ggcgcacuaa      780

uguauccaaa cuacgcauuu agagaaacau ccaacuacuc ccuaccccaa gacgauauag      840

augguaucca agcaauauac ggacuauccu caaauccaau acaaccaaca ggccccucua      900

caccaaaacc augcgaccca ucccuuacau ucgacgcaau aacaacccuc cgaggagaaa      960

uauuauucuu uaaagacaga uacuucugga gaagacaccc ucaacuccaa cgaguugaaa     1020

ugaacuucau aucuuuauuu uggccaucuc uaccaacagg gauccaagca gcuuacgaag     1080

auuuugaucg cgacuuaaua uuuuuauuca aaggaaauca auacugggca uuaucaggau     1140

augauauacu acaaggauac cccaaagaca uaucaaauua uggauucccc uccucagucc     1200

aagccaucga cgcugcagua uucuaccgau caaaaaccua cuucuuugua aaugaccaau     1260

uuuggagaua cgauaaucaa cgucaauuca uggaaccugg uuauccaaaa ucaauaucug     1320

gcgcauuucc cggaauagaa agcaaaguag acgcagucuu ucaacaagaa cacuucuucc     1380

acguauuuag cggaccaaga uacuacgccu uugacuuaau agcacaaaga guaacacgag     1440

uugcaagagg aaacaaaugg cuaaacugua gauacggaua aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  6854
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt6)

<400>  6854
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agucuauggc aaccauuagu auuaguuuua cuuguacucg      120

guuguugcuu cgcugcaccu agacaacguc aaucaacccu cgugcucuuu ccaggagauc      180

uucgaacuaa uuuaacagau agacaauuag cagaagaaua uuuauauagg uauggcuaua      240

cacgaguagc ugaaaugcga ggagaaagua aaagccuagg accugccuua uuacuacuac      300

aaaaacaacu aucauuacca gaaacuggag aauuagacuc cgcuacucua aaagcaaugc      360

gcaccccacg uugcggagua ccagauuuag gacgauuuca aacauuugaa ggagauuuaa      420

aauggcauca ucacaauaua acauacugga uucaaaacua cagugaagau uuacccaggg      480

caguaauaga cgaugcauuu gcaagggcau uugcauuaug gucagcuguu acuccacuca      540

cuuucacuag aguuuacagu agagaugcag auaucguaau acaauuugga guagcagaac      600

acggcgacgg auacccauuc gacgguaaag auggacuacu agcucaugcc uucccaccag      660

guccagguau acaaggagac gcacauuuug augaugauga auuauggagu uuaggcaagg      720

gaguugucgu accaacucga uuuggaaaug cugauggugc agcuugccau uuucccuuua      780

uuuucgaagg gagaucguau ucagcuugca caacagacgg aagauccgau ggucuaccau      840

ggugcucuac aacagcuaac uaugacacag acgauagauu cggauucugc ccauccgaac      900

gauuauauac ucaagaugga aaugcagacg guaaaccaug ucaauuccca uuuauauucc      960

aaggacaauc auauagcgcu ugcacaacag auggaagaag cgauggauac agauggugcg     1020

caacaacagc uaacuaugau cgagacaaac uauuuggauu uuguccaaca cgugcugauu     1080

ccacaguaau gggaggaaau ucugcuggug aacuaugugu auucccauuu acauuccuug     1140

guaaagaaua cucuacaugu acaagcgaag gcagaggcga cggaagacuu uggugugcua     1200

caacaucuaa uuuugauagu gauaaaaaau ggggauucug uccagaccaa ggauacucau     1260

uauuucuagu agcugcacau gaauuuggac augccuuagg auuagaucau aguucuguac     1320

cagaagcucu gauguauccu auguaccgau ucacugaagg accaccacuc cauaaagacg     1380

auguuaaugg aauaagacau uuguacggac ccaggccaga accagaacca agaccaccaa     1440

caacaacaac uccucaaccg acagcaccac caacaguuug uccaacagga ccccccacag     1500

uacauccauc agaaagaccu acagcaggac caacaggucc gccaucagcc ggaccaacug     1560

gaccuccaac agcaggcccc uccacagcaa caacaguacc auuaucacca guagaugaug     1620

caugcaaugu aaauauauuu gaugcuauag cagagauagg caaucaacua uaucucuuua     1680

aagacggaaa auauuggaga uucucagagg gcagaggauc aagaccccaa ggaccauuuu     1740

uaauugcaga uaaauggcca gcuuuaccaa ggaaauuaga uucagucuuu gaagagcgcc     1800

ucucaaaaaa auuauuuuuu uucucaggaa gacaagucug gguuuauacc ggagcauccg     1860

uauuaggacc aagaagauua gacaaauuag guuuaggugc ugaugucgca caaguuacag     1920

gagcuuuacg aagcggucga ggaaaaaugc uacuguucuc ugguagaaga cuauggagau     1980

uugacguaaa agcgcaaaug guagacccuc gaagcgcuag ugaaguagau agaauguucc     2040

cugguguacc ucuugacacc caugacguuu uucaauacag agaaaaagca uauuuuugcc     2100

aagaucgcuu cuacuggcga guuaguucac guagcgaacu aaaucaagua gaccaaguug     2160

gauaugucac auacgauaua cuacaauguc cagaagacua aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  6855
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt6)

<400>  6855
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacccaggug uacuugcagc cuucuuauuu uuaucaugga      120

cucacuguag agcacuccca cuaccaucag gaggagacga agaugauuua ucagaagaag      180

accuccaauu cgcagaaaga uaucuaagau cuuacuauca cccaacaaac uuagcaggua      240

uacuaaaaga aaacgcagca ucaucaauga cagaaagacu aagagaaaug caaucauucu      300

uuggauuaga aguaacagga aaacuagaug auaauacacu agacguaaug aaaaaaccca      360

gaugcggagu accugaugua ggagaauaca acguauuccc aagaacacua aaauggucaa      420

aaaugaaucu aacauacaga aucguaaacu auaccccaga caugacacau agugaaguag      480

aaaaagcauu caaaaaagca uucaaaguau ggucagacgu aacaccauua aacuucacca      540

gacuucacga uggaauagca gacauuauga uuucauuugg cauaaaagaa cauggcgacu      600

ucuacccauu cgacggucca agcgguuuac uagcccaugc auucccaccu ggaccuaacu      660

auggcggaga cgcacacuuu gacgaugacg aaacauggac caguucaagu aaaggauaca      720

aucuauuuuu gguagcugcc cacgaauucg gccacucacu aggacuagac cauucaaaag      780

acccuggugc auuaauguuc ccaauauaua ccuauacagg aaaaucacau uucauguuac      840

cagaugauga uguacaaggc auccaaucau uauacggccc aggagacgaa gauccaaacc      900

caaaacaccc aaaaacacca gacaaaugcg acccuucacu aucucuagac gcaauaacuu      960

cuuuaagagg agaaacaaug auauucaaag aucgauucuu cuggagacuu cacccacaac     1020

aaguagaugc agaacuauuc uuaacaaaau cuuucuggcc agaacuacca aaccguaucg     1080

acgcagcaua ugaacaccca ucacaugacu uaauauuuau auuuagagga cgaaaauuuu     1140

gggcauuaaa cggauaugau auauuagaag gauacccuaa aaaaauauca gaacucggau     1200

uaccaaaaga aguuaaaaaa auaucggcag cuguacacuu cgaagacaca ggcaaaaccc     1260

uauuauuuuc aggaaaccaa guauggcgau augacgacac aaaucauaua auggauaaag     1320

auuacccaag auuaauagaa gaagauuucc caggaauagg ugacaaagua gacgcaguau     1380

acgaaaaaaa ugguuacaua uauuuuuuua acggacccau acaauucgaa uacucaauau     1440

ggucaaacag aauaguacga gucaugccag caaauucgau acuuuggugc uaaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6856
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt6)

<400>  6856
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacaccaa acacaacaga agacuacgau acaacaacug      120

aauucgacua cggagacgca acaccauguc aaaaagucaa cgaacgagca uucggagcac      180

aauuacuacc uccacuauac ucauuaguau uuguaauagg cuuagucgga aacauacuag      240

uaguacuagu uuuaguucaa uacaaaagac uaaaaaacau gacaucuaua uacuuacuaa      300

acuuagcaau aucagaucuu cuauucuuau ucacccuucc auucuggaua gacuacaaau      360

uaaaagacga cuggguauuc ggcgacgcaa ugugcaaaau auuauccgga uucuauuaca      420

caggacuaua cucagaaaua uuuuucauaa uacuccuaac aauagacaga uaccuagcaa      480

uaguucacgc aguauucgcu uuaagagcaa gaaccguaac auucggaguu auaacaucaa      540

uuauaaucug ggcacuagcc auacuagccu caaugccagg acuauacuuc ucuaaaacuc      600

aaugggaauu cacacaccau acauguucac uccacuuucc ccaugaaucc uuaagagaau      660

ggaaacucuu ccaagcacua aaauuaaacu uauucggacu aguauuacca cuacuaguaa      720

ugauaauaug cuacacagga auuauaaaaa uccuacuuag aagaccaaac gaaaaaaaau      780

caaaagcagu cagacuaaua uucgucauaa ugauaaucuu uuuuuuauuc uggacaccuu      840

acaaucucac uaucuuaaua ucaguuuucc aagacuuccu auucacacac gaaugugaac      900

aaucaagaca cuuagacuua gcaguacaag ucacugaagu aauagcauac acacacugcu      960

gcguaaaccc aguaaucuac gcauucguag gagaaagauu uagaaaauac cuaagacaac     1020

uauuccacag aagaguugcu guacaccuag uaaaaugguu acccuucuua ucagucgauc     1080

guuuagaaag agucucauca acaucacccu caacagguga acacgaacua ucagccggau     1140

uuuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  6857
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt6)

<400>  6857
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agaacauuag caugcuuauu acuauuagga uguggauacu      120

uagcacacgu auuagcggaa gaagcagaaa uaccaagaga aguaauagaa agacuagcac      180

gaucacaaau acacucaaua agggaccuac aaagauuacu agaaauagac ucaguaggaa      240

gcgaagacuc acuagacaca ucauuaagag cacacggagu acacgcaaca aaacacguac      300

cagaaaaaag accacuacca auaagaagaa aaagaagcau agaagaagca guaccagcag      360

uaugcaaaac aagaacagua auauaugaaa uaccacgauc acaaguagac ccaacaucag      420

caaacuucuu aauauggcca ccaugcguag aagugaaaag augcacaggc ugcugcaaca      480

caucgucagu aaaaugccaa ccaagcagag uacaccacag aucaguaaaa guagcuaaag      540

uagaauacgu aagaaaaaaa ccaaaacuaa aagaaguaca aguaagacua gaagaacacc      600

uagaaugcgc augcgcaaca acaagccuaa acccagacua ccgagaagaa gauacaggaa      660

gaccgcgaga aaguggaaaa aaacgaaaaa gaaaaagacu aaaaccaacc uaaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  6858
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt6)

<400>  6858
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aauagaugcu gggcacuauu cuuaagcuua uguugcuacu      120

uaagacuagu aucagcagaa ggagauccaa uaccagaaga auuauacgaa augcuaagcg      180

accacucaau cagaagcuuu gacgauuuac aaagacuacu acauggagau ccaggagaag      240

aagacggagc agaacuagac uuaaauauga caagaucaca cucaggagga gaauuagaau      300

cacuagcaag aggaagaaga agucuaggau cacuaacaau agcggaacca gcaaugauag      360

cagaauguaa aacacgaaca gaaguauucg aaauaucaag aagauuaaua gacagaacaa      420

augcaaacuu ccuaguaugg ccaccaugcg uagaaguaca aagaugcuca ggauguugca      480

auaacagaaa cguacaaugu aggccaacac aaguacaauu aagaccagug caaguaagaa      540

aaauagaaau aguacguaaa aaaccaauau uuaaaaaagc aacaguaaca cuagaagacc      600

aucuagcaug uaaaugcgaa acaguagcag cggccagacc aguaacaaga agcccaggag      660

gaagucaaga acaaagagca aaaacaccac aaacuagagu uacaauaaga acaguaagag      720

uaagaagacc accaaaagga aaacauagaa aauucaaaca cacacaugau aaaacagcac      780

uaaaagaaac cuuaggagca ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  6859
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt6)

<400>  6859
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcuuauucg gacuacuacu ccuuacuuca gcacuagcag      120

gacaaagaca aggaacacaa gcagaaucaa accuaagcuc aaaauuccaa uuuucaucaa      180

acaaagaaca aaauggagua caagauccac aacacgaaag gauuauuaca gucucaacaa      240

acggaaguau acacagucca agauucccac auacauaccc aagaaacaca guuuuagucu      300

ggcgacuagu agcaguagaa gaaaauguau ggauacaacu aacauucgau gaaagauucg      360

gauuagaaga cccagaagac gacauaugca aauaugacuu uguagaaguc gaagaaccaa      420

gugacgguac aauacuagga agauggugcg gaucaggaac aguaccaggc aaacaaauaa      480

guaaaggaaa ccaaauuaga auaagauucg uaucagauga auacuuucca ucagaaccag      540

gauucugcau acauuacaac auaguaaugc cacaauucac cgaagcaguu ucaccaucag      600

uuuuaccacc aagugcccuc ccauuagacc uacuaaacaa cgcaauaacu gcauucagua      660

cucuagaaga ccuaauaaga uaccuagaac cagaaagaug gcaauuagau cucgaagacc      720

uauauagacc aacauggcaa cuauuaggca aagcauuugu auucggaaga aaaucaagag      780

uaguagacuu aaaccuauua acagaagaag uaagacuaua cagcugcaca ccaagaaacu      840

uuucaguuuc aauaagagaa gaauuaaaaa gaacagauac aaucuucugg ccaggauguc      900

uauuagucaa aagaugcggc ggaaacugcg caugcugccu acauaacugc aacgaaugcc      960

aaugcguacc aaguaaagua acaaaaaaau accacgaagu auuacaacua agaccaaaaa     1020

cuggaguaag aggucuacac aaaucacuaa cugacguagc auuagaacau cacgaagaau     1080

gugacugcgu cugcagagga ucaacaggag gauaaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  6860
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt6)

<400>  6860
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagacuaa uauucguaua cacacucaua ugcgcaaauu      120

ucugcucaug uagagacaca ucagcaacac cacaaucagc aucaauaaaa gcacuaagaa      180

acgccaaccu aagacgagac gauuuauaca gaagagacga aacaauacaa guaaaaggua      240

acggauaugu acaaucacca agauucccaa acaguuaccc aagaaaucua cuacuaacau      300

ggagacuaca cucacaagaa aacacaagaa uacaacuagu auuugacaac caauuuggac      360

uagaagaagc ugaaaacgac auauguagau augacuucgu agaaguagaa gacauaagug      420

aaacaucaac aauaauuaga ggaagauggu gcggccacaa agaaguacca ccccgaauaa      480

aaucaaggac aaaccaaauc aaaauaacuu ucaaaucaga cgacuacuuu guagcaaaac      540

caggcuuuaa aauauacuau agcuuacuag aagacuucca accagcagcc gcaagugaaa      600

caaacuggga aagcguaaca ucaagcaucu caggaguaag cuauaacuca ccaucaguaa      660

cagacccaac acuaauagca gacgcauuag acaaaaaaau agcagaauuc gacacaguag      720

aagauuuauu aaaauacuuc aacccagaau cauggcaaga agaccuagaa aauauguacc      780

ucgacacacc aagauauaga ggaagaagcu aucacgauag aaaaucaaaa guagaccuag      840

acagacuaaa ugacgacgcu aaacgauaua guuguacacc aagaaacuac agugucaaca      900

uacgagaaga acuaaaacua gcaaacguag uauucuuucc acgaugucua cuaguacaaa      960

gauguggagg aaacugcgga ugcggaacag uaaauuggag aucaugcacc ugcaacagcg     1020

gaaaaacagu uaaaaaauac cacgaaguac uacaauucga accuggccac auaaaacgaa     1080

ggggaagagc aaaaaccaug gcacuaguag auauccaacu agaucaucac gagagaugug     1140

acuguauaug uaguucaaga ccaccaagau aaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  6861
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt6)

<400>  6861
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaacacacu caaaauuccc agcagcagga augucaagac      120

cauuagacac aucauuaaga cuaaaaacau ucucaucaaa aucagaauau caacuaguag      180

uaaacgcagu aagaaaacua caagaaucag gauucuacug gucagcagua acaggaggag      240

aagccaaccu acuccuauca gcagaaccag caggaaccuu ccuaauaaga gacucaucag      300

accaacgaca cuucuucaca cuaucaguaa aaacacaauc cggaacaaaa aaccucagaa      360

uacaaugcga aggaggauca uucucacuac aaucagaccc acgcuccaca caaccaguac      420

caagauucga cugcguacua aaacuaguac accacuacau gccaccacca ggagccccau      480

cauuuccauc accaccaaca gaaccaucau cagaaguacc cgaacaacca ucagcacaac      540

cacuccccgg aucaccacca agaagagcau acuacauaua cucaggagga gaaaaaauac      600

cauuaguacu auccagacca uuaucuucaa acgucgcaac acuacaacau cuaugcagaa      660

aaacaguaaa cggacacuua gacucauacg aaaaaguaac ccaacuacca ggccccauac      720

gagaauuccu agaccaauac gacgcaccac uauaaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  6862
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt6)

<400>  6862
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaccaucag caggacaauu agcauuauuc gcauuaggaa      120

uaguauuagc agcaugucaa gcauuagaaa auucaacauc accacuauca gcagauccac      180

caguagcagc agcuguagua ucacauuuua augacugucc agauucacau acucaauucu      240

guuuucaugg aacauguaga uucuuaguac aagaagacaa accagcaugu guaugucauu      300

caggauaugu aggagcaaga ugugaacaug cagauuuauu agcaguaguc gcagcaucac      360

aaaaaaaaca agcaauaaca gcauuaguag uaguaucaau aguagcauua gcaguacuaa      420

uuauaacaug uguacuaaua cauuguuguc aaguaagaaa acauugugaa uggugcagag      480

cauuaauaug uagacaugaa aaaccaucag cauuauuaaa aggaagaaca gcauguuguc      540

auucagaaac aguaguauaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  6863
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt6)

<400>  6863
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaccuagcg gacucagauu auuacccuua cuacucccac      120

uccuauggcu acuaguacua acuccaggaa gaccagcagc aggacuaagu acauguaaaa      180

cuauagacau ggaauuagua aaaagaaaaa gaauagaagc cauacgugga caaauccuau      240

cuaaauugag acuagccuca ccuccaucac aaggagaagu accaccagga ccccuacccg      300

aagcaguacu agcacuauac aacucaacaa gagauagagu agcaggagaa ucagcagaac      360

cagaaccaga accagaagca gauuauuacg caaaagaagu aacacgcgua uuaaugguag      420

aaacacauaa cgaaauauau gauaaauuca aacaaucuac acacucuaua uacauguucu      480

uuaauacauc agaacucaga gaagccguac ccgaaccagu auuauuauca agagcagaac      540

uaagacuucu aagacuaaaa cucaaaguug aacaacacgu agaacuauac caaaaauacu      600

caaacaauuc uuggagauau uuaucuaaca gacuacuagc ccccucagac uccccugaau      660

ggcuaucauu cgacguaaca ggaguaguca gacaaugguu aucuagagga ggagaaauag      720

aaggauuccg acuuucagca cacuguucuu gugauagucg cgacaacaca uuacaaguag      780

acauaaacgg uuucacaacu ggacguagag gagaccuugc aacaauacau gguaugaaca      840

gaccauucuu acuacuaaug gcaacaccac ucgaacgagc acaacaucua caauccucac      900

gccacagacg agcccuagac acaaacuacu gcuucucauc aaccgaaaaa aauuguugcg      960

uaagacaauu auacauagau uucagaaaag accuaggaug gaaauggaua caugaaccua     1020

aaggauacca cgccaauuuu uguuuaggcc cauguccaua cauaugguca cuagacacac     1080

aauacucuaa aguauuagcu cuauacaacc aacacaaccc aggcgcauca gcagcaccau     1140

gcuguguucc acaagcuuua gaaccauuac caaucguaua uuacguagga agaaaaccca     1200

aaguagaaca auuaucaaac augauaguca gaucauguaa augcucuuaa ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  6864
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt6)

<400>  6864
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauuacugcg uacuaucagc auuccuaaua cuacaccuag      120

uaacaguagc auuaucccua ucaacuugcu ccacccuaga cauggaccaa uuuaugagaa      180

aacgcauaga agcaauaaga ggacaaauuu uaucaaaacu caaacuaaca agcccaccag      240

aagacuaccc agaaccagaa gaaguaccac cggaagucau uucaauauac aauucaacaa      300

gagaccuacu acaagaaaaa gcaucaagaa gagcugcagc augugaaaga gaacgcagcg      360

acgaagaaua cuacgcaaaa gaaguauaca aaaucgacau gccuccauuc uucccaagcg      420

aaaacgcaau accaccaaca uucuaucgac cauauuuuag aauaguaaga uucgacgucu      480

cagccaugga aaaaaaugcu agcaauuuag uaaaagcaga auuuagaguu uucagacuac      540

aaaacccaaa agcacgaguc cccgaacaac gaauagaauu auaccaaaua cuaaaaucaa      600

aagaccuaac auccccaaca caaagauaca uagacucaaa aguaguuaaa acccgagcag      660

aaggcgaaug gcuaucuuuc gauguaacag acgcaguaca cgaaugguua caccacaaag      720

auagaaaccu agguuucaaa auaucucucc acugcccaug cugcacauuc guaccaucca      780

acaacuacau aauaccaaac aaaucugaag aauuagaagc aagauucgca ggaauagacg      840

guacaucaac cuacacauca ggagaucaaa aaacaauaaa auccacaaga aaaaaaaauu      900

caggaaaaac accacaccua cuacuaaugc uacuaccaag cuacagauua gaaucacaac      960

aaacaaacag acgaaaaaaa agagcacuag augcagcaua cugcuucaga aacguacaag     1020

acaacugcug ucuccgccca cuauacauag auuucaaacg agauuuagga uggaaaugga     1080

uacacgaacc caaaggauau aacgccaacu ucugcgcagg agcaugccca uauuuauggu     1140

cauccgacac ccaacacucc agaguccuau cucucuacaa caccauaaac ccagaagcau     1200

cagcaucacc cugcugugua ucccaagacu uagaaccacu uacaauauua uacuacauag     1260

gaaaaacacc aaaaauagaa caacuaucaa acaugauagu caaauccugu aaaugcucau     1320

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  6865
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt6)

<400>  6865
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaugcacu uacaaagagc auuaguugua cuagcacuuc      120

ucaacuuugc aacaguauca cuaucauuau caaccugcac aacacuagac uuuggacaca      180

uaaaaaaaaa acgaguagaa gccauaagag gacaaauacu aucaaaacua agacuaacau      240

caccaccaga accaaccgua augacacacg ucccauacca aguauuagcc cuauacaaca      300

guacaagaga acuacucgaa gaaaugcacg gagaacgaga agaaggaugc acucaagaaa      360

auacagaauc agaauacuac gcaaaagaaa uacacaaauu ugauaugaua caaggauuag      420

cagaacacaa ugaacuagcc guaugcccaa aaggaauaac aucaaaagua uuuagauuua      480

acguaucauc agucgaaaaa aaccgcacaa aucuuuucag agcagaauuu cgagugcuac      540

gaguaccaaa uccaucauca aaaagaaacg aacaacgcau agaacuauuu caaauccuac      600

gaccagacga acacauagca aaacaaagau acauaggagg caaaaaccuc cccacaagag      660

guaccgcaga augguuauca uucgauguca ccgacacagu acgagaaugg uuacuaagaa      720

gagaaucaaa ccuaggcuua gaaauaucaa uccacugccc augccacacc uuucaaccaa      780

auggagacau auuagaaaac auacacgaag uuauggaaau aaaauucaaa ggaguagaua      840

augaagauga ccacggacga ggugaucuug gaagacuaaa aaaacaaaaa gaccaccaca      900

acccacaucu aauauuaaug augauaccuc cacacagauu agacaacccc ggacagggag      960

gacaaagaaa aaaaagagca cuagauacaa acuauugcuu cagaaaccua gaagaaaacu     1020

gcugcgucag accuuuauac auagauuuca gacaagaucu cggauggaaa uggguccacg     1080

aaccaaaagg auacuaugca aacuuuugcu ccggccccug cccauaucua cgaucagcag     1140

acacaacaca cucaacagua cucggacuuu auaacacucu aaaccccgaa gcauccgccu     1200

ccccaugcug uguuccacaa gacuuagaac cacuaacaau auuauacuau guaggacgaa     1260

caccaaaagu ugaacaauua agcaacaugg uaguaaaauc augcaaaugu agcuaaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6866
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt6)

<400>  6866
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacccguag cugucugggc agcauuagca guuggauuag      120

aauuaugggc agcugcccac gcacuaccag cccaaguagc auucacaccu uacgccccag      180

aaccuggauc uaccugcaga cuaagagaau auuacgauca aacagcucaa auguguuguu      240

caaaauguuc accaggccaa caugcaaaag uauucuguac aaaaacauca gauacaguau      300

gugauucaug cgaagauuca acuuauacac aauuauggaa uuggguuccc gaaugccuau      360

ccuguggauc aagauguuca ucagaucaag uagaaaccca agcauguaca agagaacaaa      420

auagaauaug uacaugcaga ccagguuggu auugugcacu aagcaaacaa gaaggaugca      480

gauuaugugc cccauuaaga aaaugucgac caggcuucgg aguagcacga ccuggaaccg      540

aaaccucuga uguaguaugc aaaccaugug caccaggaac auuuucaaac acaacaucuu      600

caacagacau augcagacca caccaaauau guaacguugu agcaauaccu ggcaaugccu      660

caauggaugc aguuuguaca ucaacauccc caacaagauc uauggcacca ggagccguac      720

auuuaccaca accaguuagu acucgaucac aacauaccca acccacaccc gaaccaucca      780

cugcuccguc caccucauuc cuacuaccaa ugggacccuc uccaccagcu gaagguucua      840

caggagacuu cgcacuacca guuggauuaa uaguaggagu aaccgcacua ggacuucuaa      900

ucauaggagu aguuaauugu guaaucauga cucaaguuaa aaaaaaaccu uuauguuuac      960

aacgagaagc aaaaguacca cauuuaccgg cagauaaagc aagaggaacu caaggaccag     1020

aacaacaaca ucuauuaauu acagcuccau caucaucauc aucaucacua gaaucaucag     1080

cuucagcacu ugaucgaaga gcaccuacac guaaccaacc acaagcacca gguguggaag     1140

cuucaggugc aggagaagca agagcaagua caggaucauc agacaguuca ccaggagguc     1200

auggaacaca aguaaaugua acuuguauag uaaaugucug uagcucauca gaucauucau     1260

cccaaugcuc aucucaagcc uccucaacaa ugggagacac agauuccucu ccaucagaau     1320

caccaaaaga cgaacaagua ccauuuucaa aagaagaaug ugccuucaga ucacaacuag     1380

aaacaccaga aacuuuauua ggaucaacug aagaaaaacc gcuacccuua ggaguaccag     1440

acgccggaau gaaacccucu uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  6867
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt6)

<400>  6867
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaguaauga gauuauuucc auguuuucua caauuauuag      120

caggauuagc acuaccagca guaccaccac aacaaugggc auuaucagca ggaaauggaa      180

guucagaagu agaaguagua ccauuucaag aagugugggg aagaucauau uguagagcau      240

uagaaagauu aguagaugua guaagugaau auccaaguga aguagaacau auguuuucac      300

caaguugugu aaguuuauua agauguacag guuguugugg agaugaaaac cuacauugug      360

uaccaguaga aacagcaaau guaacaaugc aauuauuaaa aauaagaagu ggagauagac      420

caucauaugu ugaauuaaca uuuagucaac auguaagaug ugaaugcaga ccacuaagag      480

aaaaaaugaa accagaaaga agacgaccaa aaggaagagg aaaaagaaga agagaaaaac      540

aaagaccaac agauugucau uuauguggag augcaguacc aagaagauaa ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  6868
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt6)

<400>  6868
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagauagac aaacugauac agcaccgagu ccgaguuauc      120

auuuauuacc aggaagaagg agaacaguag augcagcagc aucaagagga caaggaccug      180

aaccagcacc aggaggaggg guagaaggag uuggagcuag aggaguagca uuaaaauuau      240

uuguccaguu auuaggaugc aguagauuug gaggagccgu aguaagggca ggagaagcag      300

aaccaucagg ggcagcacga agugcaucaa guggaagaga agaaccacaa ccagaagaag      360

gagaagaaga agaggagaaa gaagaagaaa gaggaccaca auggcggcug ggugcgagaa      420

aaccaggaag uuggacagga gaagcagcag uaugcgcaga uucagcuccc gcagcgagag      480

caccucaagc auuagcaaga gcaagcggaa gaggaggaag aguagcaaga agaggagcag      540

aagaaucagg gccaccucau agcccaagua gaagggguag ugcaaguaga gcaggaccag      600

gaagagcaag cgaaacaaug aauuuuuuau uaagcugggu acauugguca uuagcgcuau      660

uacuauauuu acaucaugca aaauggagcc aagcagcacc aauggcagaa ggaggagguc      720

aaaaccauca cgaaguagua aaauuuaugg auguuuauca aaggucauac ugccacccaa      780

uagaaacacu aguagauaua uuucaagaau acccagacga aauagaauau auauuuaaac      840

caagcugugu accacuaaug agauguggug gauguugcaa cgaugaagga cuagaaugug      900

uaccaacaga agaaucuaau auaacaaugc agauaaugag aauaaaacca caccaaggac      960

aacauauagg agaaaugagu uuuuuacaac auaauaaaug ugaauguaga ccaaaaaagg     1020

auagagcaag gcaagaaaaa aaaucaguaa gaggcaaagg aaaaggacaa aaaaggaaaa     1080

gaaaaaagag cagauauaaa aguuggagcg uguauguagg agcaagaugc ugucuaaugc     1140

cauggucacu accaggaccu cauccaugug gaccauguag ugaacgaaga aaacaucuau     1200

uuguacagga uccacaaaca uguaaaugua gcuguaaaaa uacagauagu agauguaaag     1260

caaggcaauu agaauuaaau gaaaggacuu guagaugcga uaaaccuaga agguagggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6869
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt6)

<400>  6869
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuucuau uaagcugggu acauugguca cuugcauuau      120

uacuauauuu acaucacgca aaauggagcc aagcagcacc aauggcagaa ggaggaggac      180

aaaaccauca cgaaguagua aaauuuaugg auguauauca aaggaguuac ugccauccaa      240

uagaaacacu aguggacaua uuccaagaau auccagauga aauagaauau auauuuaaac      300

caagcugugu accacuaaug agauguggag gaugcuguaa cgaugaagga cuagaaugcg      360

uaccaacaga agaaagcaau auaacaaugc aaauaaugag aauaaaacca caccaaggac      420

aacacauagg agaaauguca uucuuacaac auaacaaaug cgaaugcaga ccaaaaaaag      480

aucgagcaag acaagaaaaa aaaucaguaa gaggaaaagg aaaaggacaa aaaagaaaaa      540

gaaaaaaaag cagauacaaa aguuggagcg uauacguagg agcaagaugu ugcuuaaugc      600

cauggucacu accaggacca cacccaugcg gacccuguag cgaaagaaga aaacaucuau      660

ucguacaaga cccacaaaca ugcaaaugcu caugcaaaaa cacagacuca agauguaaag      720

caagacaacu agaacuaaau gaaagaacau guagauguga caaaccaaga agauaaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  6870
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt6)

<400>  6870
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaccauuac uaagaagacu auuacuagca gcauuauuac      120

aacuagcacc agcacaagca ccaguaucac aaccugaugc accaggacau caaagaaaag      180

uaguaucaug gauagaugua uauacaagag caacaugcca accaagagaa guaguaguac      240

cacuaacagu agaauuaaug ggaacaguag caaaacaauu aguacccuca ugcguaacag      300

uacaaagaug cggagguugu uguccagacg auggacuaga auguguaccu acaggucaac      360

aucaaguaag aaugcaaaua uuaaugauaa gauacccaag uucacaauua ggagaaaugu      420

cauuagaaga acauucacaa ugcgaaugua gaccaaaaaa aaaagacuca gcaguaaaac      480

cagacagagc agcaacacca caccauagac cucaaccaag aucuguacca ggaugggacu      540

cagcaccagg agcuccauca ccagcagaca uaacucaucc aacaccagca ccaggacccu      600

cagcacaugc agcuccauca acuacaucag cauuaacacc aggaccagca gcagcugcug      660

cagacgcagc agccucauca guagcaaaag gaggagcaua aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  6871
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt6)

<400>  6871
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuauuag gauuuuucuc aguagcaugu ucauuacuug      120

cagcagcauu acuccccgga ccaagagaag caccagcugc agcagcagca uucgaaucag      180

gacuagaccu aagcgaugca gaaccagacg caggagaagc aacagcauau gcaaguaaag      240

accuagaaga acaauuaaga aguguaucau caguagacga acuaaugaca guacucuacc      300

ccgaauacug gaaaauguac aaaugccaau uaagaaaagg aggauggcaa cacaacagag      360

aacaagcuaa ccuaaacuca agaacugaag aaacaauaaa auuugcagca gcccacuaca      420

auacagaaau auuaaaauca aucgauaacg aauggcgaaa aacacaaugu augccaagag      480

aaguuuguau agacguagga aaagaauuug gaguugcaac aaauacauuu uuuaaaccac      540

caugcgucuc aguauacaga ugcggaggau gcugcaauag cgaaggauua caauguauga      600

auacaucaac aagcuacuua agcaaaacac uauuugaaau aacaguaccc uuaucacaag      660

gacccaaacc aguuacaaua aguuuugcaa aucauacuuc augcagaugu augaguaaau      720

uagauguuua ucgccaagua cauucaauaa uacgacgcag ucuaccagca acauuaccac      780

aaugccaagc ugcaaauaaa acaugcccaa cuaauuauau guggaauaau cacaucugca      840

gaugucuugc acaagaagac uucauguuuu ccucagaugc aggagacgau ucaacagacg      900

gcuuccacga cauaugugga ccaaauaaag aacuagauga agaaacaugu caaugcgucu      960

gcagagcagg auuaagacca gcaucaugug gaccacacaa agaauuagac aggaauuccu     1020

gccaaugugu auguaaaaau aaacuauuuc caucacaaug cggagccaau cgagaauucg     1080

acgaaaauac augccaaugu gucuguaaaa gaaccugucc cagaaaucaa ccauuaaacc     1140

cuggaaaaug ugccugugaa ugcacagagu caccacaaaa auguuuacua aaaggaaaaa     1200

aauuccauca ucaaacaugc uccuguuaca gaagacccug cacaaacaga caaaaagcau     1260

gcgaaccagg auucagcuac agugaagaag uaugcagaug uguaccauca uauuggaaac     1320

gaccacaaau gucauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  6872
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt6)

<400>  6872
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagaau ggguaguagu aaacguauuc augaugcuau      120

acguacaauu aguacaaggu uccucaaacg aacacggccc aguaaaaaga ucaucccaaa      180

gcacacuaga aagaucugaa caacaaauaa gagcagcauc uucacuagaa gaacuuuuaa      240

gaauaacaca cucagaagac uggaaacuau ggagaugcag acuaagacua aaaucauuca      300

caucuaugga cagcaggucc gcaagucaca gaucaaccag auucgccgca acauuuuaug      360

acauagaaac acucaaagua auagacgaag aauggcaaag aacacaaugc aguccaagag      420

aaacaugugu agaaguagcc ucagaacuag gaaaaagcac uaacacauuc uucaaaccac      480

caugcguaaa uguauucaga ugcggcggau guugcaacga agaaucucuc auauguauga      540

acacaaguac aucauacauc ucaaaacaac uauucgaaau aucaguccca uuaacaucag      600

uaccagaacu aguaccagua aaaguagcaa accacacagg auguaaaugc cuaccaacag      660

caccaagaca cccauacagu aucauaagaa gaucaaucca aauaccagaa gaagaccgau      720

gcucccacuc aaaaaaauua ugcccaauag acaugcuaug ggauucaaac aaaugcaaau      780

gcguacuaca agaagaaaac ccauuagcag gaacagaaga ccacucucac uuacaagaac      840

cagcauuaug cggaccacau augauguucg acgaagauag augugaaugu guaugcaaaa      900

cuccaugccc aaaagaccua auacaacacc caaaaaacug cucauguuuc gaaugcaaag      960

aaucucuaga aacaugcugc caaaaacaca aauuauuuca cccagacaca ugcucaugcg     1020

aagacagaug cccuuuccac accagaccau gugccagcgg aaaaacagca ugugcaaaac     1080

acuguagauu uccaaaagaa aaacgagcag cccaaggacc acacucaaga aaaaauccau     1140

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  6873
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt7)

<400>  6873
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcgaug agaccggcuu cgaacacucc gggcuguggg      120

ugaguguccu cgccggucug uugcugggcg caugccaggc ccaucccauc ccagacagcu      180

ccccgcuccu gcaauuuggg ggccagguga ggcagcggua cuuguauacu gaugacgcgc      240

agcaaaccga ggcccaccug gaaauucgcg aggaugguac gguagggggc gcagccgacc      300

agagucccga aagccuccug cagcugaagg cacucaaacc aggcgugauc cagauucugg      360

gggucaagac uuccagguuc uugugucaac ggcccgaugg ugcccuguac ggcagccucc      420

auuuugaccc agaggcgugc uccuuccgcg agcugcuguu ggaagauggg uauaacgugu      480

accagaguga ggcccacggc cucccccugc aucugccagg uaauaaaagc ccgcacaggg      540

accccgcacc acgggggccc gcccgcuuuc ucccacugcc cggcuugccg cccgcccugc      600

cagaaccccc aggcauccuc gcaccccagc caccggaugu gggguccagc gacccccuga      660

guauggucgg uccaucccag ggcaggagcc ccuccuaugc caguugagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  6874
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt7)

<400>  6874
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc ccccacugcu ccuguugcug uucuggggcg      120

uggucuccca uaguuucccg gccacccucg agacucagga acaagacgug gaucugguac      180

agaaguacuu ggagaaauau uacaaccuga agaaugacgg gaggcaagug gaaaaacggc      240

gcaacagcgg ucccgucgug gagaagcuca aacagaugca ggaauuuuuc ggccugaagg      300

ugaccgggaa gccagaugca gagacgcuga aagucaugaa gcagcccagg ugcggcgugc      360

cagacguagc ccaguuugug cucacugagg guaauccccg gugggaacag acccaccuga      420

ccuaucgcau cgagaacuac acuccagauu ugccgagggc ggacgucgau caugccauug      480

aaaaagcauu ccaacugugg uccaauguga cgccccucac cuuuacuaag gugagugagg      540

ggcaggccga caucaugauu agcuucgucc ggggcgauca ccgcgacaac uccccauuug      600

auggccccgg ggguaaucug gcacaugccu uccagccagg ccccgggauc ggcggugacg      660

cgcacuuuga ugaggacgaa agguggacca acaauuuccg ggaguauaac cugcaccgcg      720

uggccgcaca ugaauugggg cacagccucg gccuguccca uaguacugac auuggcgccc      780

ugauguaccc gagcuauacc uucuccgggg auguacagcu cgcccaagac gauaucgacg      840

guauccaggc aauuuacggc aggagccaga aucccgugca accaaucggg ccccagaccc      900

caaaagccug ugauaguaag cugacguuug acgcgauuac uaccauccgg ggcgagguca      960

uguucuuuaa agaucgcuuc uacaugagga cuaaccccuu uuauccagaa guggaguuga     1020

auuucauuuc cguguuuugg ccgcagcugc ccaacggucu cgaggccgca uacgaguucg     1080

ccgaccggga ugaaguccgc uuuuucaagg gcaauaagua uugggcagug caggggcaaa     1140

acguacugca cggcuaccca aaagacaucu auagcuccuu uggguucccc aggaccguga     1200

agcacauuga ugccgcccug agugaagaga acaccgguaa aacuuacuuu uucgucgcga     1260

auaaguauug gcgguacgac gaauacaaac gcagcaugga cccaggcuau cccaagauga     1320

ucgcacauga uuucccgggg aucggccaca agguggacgc cgucuuuaug aaagaugguu     1380

ucuuuuacuu cuuucauggc acgaggcagu auaaguucga cccaaaaacc aagcggauuu     1440

ugacucucca gaaagccaac uccugguuua auugcaggaa gaacugagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  6875
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt7)

<400>  6875
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuuuc ccccacugcu ccuguugcug uucuggggcg      120

uggucuccca uaguuucgug cucaccgagg ggaacccgag gugggaacag acucaccuga      180

ccuaccggau cgagaauuau acgcccgacu ugccacgcgc cgauguagac caugcaauug      240

aaaaggccuu ucaacugugg agcaacguga cuccccucac cuucaccaaa gucuccgagg      300

gucaggcgga uaucaugauu aguuuuguga ggggcgacca ccgggauaau agcccauucg      360

acgggcccgg cgguaaccug gcccaugcau uucagccagg gccgggcauc ggcggggaug      420

cccacuucga cgaagaugag cgcuggacua auaacuuuag ggaguacaau cugcaccggg      480

uggcagccca ugaacucggu cacucccugg gcuugagcca uuccaccgac auuggggcgc      540

ugauguaucc caguuacacg uucagcggcg auguccagcu cgcccaagac gauaucgacg      600

guauccaggc aauuuauggg cgcucccaga acccagugca gcccaucggc ccacaaacuc      660

ccaaggccug cgacagcaaa cugaccuuug augccauuac uaccaucagg ggcgagguaa      720

uguucuucaa ggaccgguuu uacaugcgca ccaauccguu cuaucccgaa guggagcuga      780

acuuuauuag ugucuucugg ccacaguugc ccaaugggcu cgaggcagcc uacgaauuug      840

cggauaggga cgaggugcgg uucuuuaaag guaacaagua cugggccgug cagggccaga      900

auguccugca cggguaucca aaggauaucu acuccagcuu cggcuuuccc cgcacgguga      960

aacacauuga cgcagcccug uccgaagaga acacugguaa gaccuauuuc uuuguagcaa     1020

auaaauacug gagguaugau gaauacaagc ggaguaugga cccaggcuau ccgaaaauga     1080

ucgcccauga uuuccccggg aucggccaca agguggacgc cgucuuuaug aaagaugggu     1140

ucuucuacuu uuuccauggu acucgccaau acaaguuuga cccaaagacc aaaaggauuc     1200

ucacccugca gaaggcgaac agcugguuca acugucggaa aaauugagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  6876
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt7)

<400>  6876
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaaaaaca uccugaagau ucucauggac agcuacucca      120

aagagaguaa gauccagacc gugaggcggg ucacuagcgu gucccuguug gccguauauc      180

ugaccaugaa uacgaguagc cucgugcugg caaaacccau ugaaaacacu aaugauaccu      240

ccaucaagaa cgucgagaag uugcgcaaug ccccaaacga agagaauagc aaaaaggugg      300

aagacuccaa aaacgauaag guggagcacg ucaaaaauau ugaggaagcg aagguggagc      360

aaguagcccc ggaagugaaa aguaagagca cccugagguc cgcaagcauc gccaacacua      420

auagugagaa guacgacuuc gaguaucuca acggccuguc cuacaccgaa cugacgaauc      480

ucaucaaaaa cauuaagugg aaucagauca acgggcuguu uaacuauagc acugguuccc      540

agaaauucuu uggcgauaag aaucgggucc aggcaauuau caacgccuug caagagagug      600

ggcgcaccua cacugcgaau gacaugaaag gcauugaaac cuucaccgag gugcugaggg      660

ccgguuuuua ucucggguac uacaacgaug gccugagcua ucugaaugac cggaacuucc      720

aggauaagug cauccccgca augauugcca uccagaagaa uccaaacuuu aaauugggca      780

cggccgugca ggacgaaguc aucacuuccc ucgggaagcu gauugguaau gcaagcgcca      840

acgcggaggu gguaaauaac ugugugcccg uccugaaaca auuccgcgag aaucucaacc      900

aguacgcccc agauuaugug aagggcaccg cagugaauga acugaucaaa gggauugagu      960

uugacuucag uggcgccgca uacgaaaagg augucaagac uaugcccugg uaugguaaaa     1020

ucgacccauu uauuaacgag uugaaggccc uggggcucua cggcaacauc accuccgcca     1080

ccgaaugggc gagcgacgug ggcaucuauu accugaguaa auucgggcug uacuccacua     1140

auaggaacga uauuguacag agcuuggaga aggcagugga cauguauaaa uacgguaaga     1200

ucgccuucgu cgccauggag cggauuacgu gggauuauga cggcaucggg agcaauggca     1260

agaaagugga ucaugacaag uuucucgaug acgcagaaaa acacuaccug ccgaagaccu     1320

auacuuucga uaacgguacc uuuauuaucc gcgccggcga caaagucucc gaggaaaaga     1380

ucaaaaggcu guacugggcg agucgggagg uaaagagcca guuccaucgc guggugggga     1440

augauaaggc ccucgaagug ggcaacgcag acgacguccu gaccaugaaa auuuuuaauu     1500

cccccgagga guauaaguuc aacacuaaua ucaacggggu gagcacggau aaugguggcu     1560

uguacauuga accaaggggg accuuuuaca cuuaugagcg gacuccccaa cagaguaucu     1620

ucucccugga ggaacucuuu cgccacgagu acacccauua ucugcaggcc agguaccugg     1680

ucgacggcuu guggggucaa ggcccauucu augagaaaaa ccggcucacc ugguuugaug     1740

aagggacggc agaguucuuu gccggcagca cccgcacuuc cggggugcug cccaggaaga     1800

guauucuggg cuaccucgcc aaagacaagg uggaucaccg guauagccug aagaaaaccu     1860

ugaacuccgg uuacgacgau agcgacugga uguucuacaa uuauggguuc gcaguagccc     1920

acuaccugua ugaaaaggau augccgacuu uuaucaaaau gaauaaggcg auucucaaca     1980

ccgacgugaa aaguuacgau gaaaucauca agaagcuguc cgacgaugcc aacaaaaaua     2040

cggaguauca gaaccauauu caggagcugg cagacaagua ccagggcgcc gguauccccu     2100

uggucagcga cgauuaucug aaagaccacg gcuacaagaa agccuccgaa guguacagug     2160

agauuagcaa ggcagcgucc cucaccaaua cuagcgucac cgccgagaaa agucaauauu     2220

ucaacacuuu uacccugagg gggacguaca ccggcgaaac uuccaagggg gaguucaagg     2280

auugggacga aaugagcaaa aagcucgaug gcacccugga guccuuggcc aaaaauagcu     2340

ggagugguua uaagacucug accgcauacu uuacgaacua ucgcgugacc agcgacaaua     2400

aagugcagua cgauguaguc uuccaugggg ugcucacuga caacgccgau aucuccaaua     2460

acaaggcacc aauugccaag gugaccggcc ccaguacugg cgcggucggg cggaauaucg     2520

aauuuagcgg uaaagacucc aaggaugagg acggcaaaau cgugagcuac gacugggauu     2580

ucggggacgg cgccaccucc agggguaaga acagugugca cgcauauaaa aaggccggga     2640

cguacaaugu aacccugaag gucacugaug acaaaggcgc caccgcaacu gagagcuuua     2700

ccauugaaau caagaacgaa gauacuacca cgccaauuac caaagagaug gagcccaaug     2760

acgauaucaa ggaagccaac ggcccaauug uggagggggu gacugucaaa ggugaccuga     2820

acggcuccga ugacgcggau accuucuauu uugacgugaa ggaagauggg gacguaacua     2880

ucgaguugcc guacaguggc agcuccaauu ucaccuggcu gguguauaaa gagggugacg     2940

aucagaacca caucgccagc gggauugaca agaauaacag uaaggucggc acguucaaau     3000

ccaccaaggg ccgccauuac guguuuaucu auaaacacga uagcgcaucc aauauuagcu     3060

acagucucaa caucaagggg cuggguaaug aaaaacucaa ggagaaggaa aacaaugacu     3120

ccagcgauaa agccacugug auucccaacu ucaauaccac uaugcagggc agucuguugg     3180

gggacgauuc ccgggacuac uauagcuuug aggucaagga agagggcgag gugaacaucg     3240

aacuggauaa aaaggacgag uucgguguaa ccuggacgcu gcauccagaa uccaauauua     3300

acgauaggau caccuacggg caaguggacg gcaauaaagu cagcaacaag gugaagcucc     3360

gccccggcaa auauuaccug uugguguaua aguacagugg gagcgguaac uaugagcugc     3420

gggucaauaa augaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  6877
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt7)

<400>  6877
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucucca      120

gugccuacag cauugcaaac acuaauuccg agaaauauga cuuugaauac uugaacggcc      180

ugaguuauac cgagcucacg aaucugauca agaacauuaa auggaaucag aucaacgggu      240

uguucaauua cagcacuggu ucccaaaagu uuuucggcga uaaaaacagg guccaggcca      300

uuaucaaugc gcugcaggaa agcgggcgga ccuauaccgc caacgacaug aagggcaucg      360

agacuuuuac cgaagugcuc cgcgcagguu ucuaccuggg guauuacaau gauggccugu      420

ccuaccucaa cgacaggaau uuucaggaua agugcauucc cgccaugauc gcaauucaga      480

aaaacccaaa uuucaagcug ggcacggccg uacaggacga ggugaucacu agcuugggga      540

aacugauugg uaacgcgagc gccaacgcag aggucgugaa uaacugugug ccgguccuca      600

agcaguuucg ggaaaaucug aaccaguaug cccccgauua cgugaaaggc accgccguaa      660

augagcugau caaggggauu gaguucgacu ucuccggcgc agccuaugaa aaagauguga      720

agacuaugcc augguacggu aagaucgacc ccuuuaucaa cgaguugaaa gcgcucgggc      780

uguauggcaa uauuaccagc gccaccgaau gggcaaguga ugucggcauc uacuaucugu      840

ccaaguucgg gcucuacagc acgaaccgca augacauugu gcaaucccug gagaaagccg      900

uggauaugua caaguauggu aaaaucgcau uugucgccau ggaaaggauu acuugggacu      960

acgacggcau cgggaguaac ggcaagaagg uggaucacga caaauucuug gaugacgccg     1020

agaagcauua ucugccaaaa accuacacuu uugauaaugg uaccuucauc auucgggcgg     1080

gcgacaaggu aagcgaagag aaaaucaagc gccucuauug ggcauccagg gaggugaaga     1140

gucaguuuca ccgggucgug gggaacgaua aagcccugga agugggcaau gccgacgaug     1200

uccugaccau gaagauuuuc aacagucccg aggaauacaa auuuaauacu aacaucaacg     1260

ggguguccac ggacaauggu ggcuuguaua uugagccacg cgggaccuuc uacacuuacg     1320

aaaggacccc gcagcagagc aucuuuaguc ucgaggagcu guuccggcau gaauauaccc     1380

acuaccugca agcacgcuau cucguagaug gccugugggg ucagggcccc uuuuacgaga     1440

agaacagguu gacuugguuc gacgaaggga cggccgaguu cuuugcgggc uccacccgga     1500

cuagcggggu gcugccacgc aaaagcaucc ucggcuaucu ggccaaggac aaggucgauc     1560

auagguacuc ccugaaaaag accuugaaua gugguuauga cgauagcgac uggauguucu     1620

acaacuacgg guuugcagug gcccacuauc ucuacgaaaa agauaugccc accuucauua     1680

agaugaauaa agcaauccug aacacugacg ucaaguccua ugaugagauu aucaaaaagc     1740

ugagcgacga ugccaauaag aacacggagu accagaauca cauucaagaa cucgccgaca     1800

aauaucaggg cgcagguauc ccacugguga gugaugacua cuugaaggau cauggcuaua     1860

aaaaggccuc cgagguguac agcgaaauuu ccaaagcggc cagucugacc aacacuagcg     1920

uaaccgcaga gaagucccag uacuuuaaua cuuucacccu ccgggggacg uauaccggcg     1980

agacuagcaa gggggaauuu aaagacuggg acgagaugag uaagaaacug gauggcaccc     2040

uggaauccuu ggccaagaac agcugguccg guuacaaaac ucugaccgcc uauuucacga     2100

auuaccgcgu gaccagugac aacaaggucc aguaugaugu ggucuuucac ggggugcuca     2160

cugacaaugc agauaucagc aacaacaagg cgcccaucgc caaagugacc ggcccgucca     2220

cuggcgcagu agggaggaau auugaguuca gcgguaagga caguaaagau gaagacggca     2280

agaucguguc cuacgauugg gacuuugggg auggcgccac cagccggggu aaaaacuccg     2340

uccaugccua caagaaagca gggacguaua augugacccu gaaggucacu gacgacaagg     2400

gcgccaccgc gacugagagc uucaccauug agaucaaaaa cgaagauacg accacuccca     2460

uuaccaagga gauggaacca aaugacgaua ucaaagaggc caacggcccc aucguggaag     2520

gggugacugu aaagggugac cucaauggca gugaugacgc agauaccuuc uacuuugacg     2580

ucaaagagga uggggacgug acuauugagc ugccauauag cggcuccagu aacuucaccu     2640

gguuggugua caaggaaggu gaugaccaaa aucacaucgc cagcgggauu gauaagaaca     2700

auuccaaagu cggcacguuu aagagcacca aaggcaggca cuauguguuc aucuacaagc     2760

augacuccgc caguaacauu agcuauuccc ugaauaucaa agggcucggu aacgagaagc     2820

ugaaggaaaa agagaauaac gacaguagcg auaaggcaac ugugaucccc aacuuuaaua     2880

ccacuaugca gggcucccug uugggggacg auagccgcga cuacuacagu uucgaaguaa     2940

aagaggaggg cgaagucaac auugagcugg auaagaaaga cgaauuuggu gugaccugga     3000

cgcuccaccc agaguccaau aucaacgauc ggauuaccua ugggcaagug gacggcaaua     3060

aggucagcaa caaagugaag cugaggccgg gcaaguacua ucuccuggua uacaaauauu     3120

ccgggagcgg uaauuacgag uugcgcguga acaagugagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  6878
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt7)

<400>  6878
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucucca      120

gugccuacag caugaaaaag aacauuuuga aaauccugau ggacuccuau aguaaggaga      180

gcaaaauuca gacugucagg cgggugaccu ccguaagccu ccuggcagug uacuugacga      240

ugaauacuuc cagucugguc cucgccaagc ccaucgaaaa caccaaugau accagcauua      300

agaacgugga gaaacugcgc aaugcgccaa acgaagaaaa uuccaagaaa guggaagaca      360

gcaagaacga uaaagucgag cacgugaaga auaucgagga agccaaagua gagcaagugg      420

caccggaagu caagaguaag uccacucuga ggagcgccuc ccggcgcagg cggaaacgca      480

ucgcaaacac caauagugag aaguaugacu uugaguaccu caacggccug agcuauacgg      540

aauugacuaa ucugauuaaa aacaucaagu ggaaucagau uaacggucuc uucaacuacu      600

ccaccgggag ccagaaauuu uucggcgaua agaauagggu gcaggccauc auuaacgcgc      660

ugcaagagag ugggcggacu uauaccgcca augacaugaa gggcaucgaa accuuuacgg      720

aggugcugcg cgcagguuuc uacuuggggu acuauaacga uggccucucc uaccugaaug      780

acaggaacuu ucaggauaaa ugcauucccg ccaugaucgc cauccagaag aauccaaacu      840

ucaaacuggg cacugcaguc caggacgaag ugauuaccag ccucgggaag cugaucggua      900

augccagugc gaacgccgag guagugaaua acuguguccc cguguugaaa caauuucggg      960

agaaucugaa ccaguaugca ccagauuacg ugaagggcac ugccgucaau gaacucauua     1020

aggggaucga guucgacuuc uccggcgcag ccuaugaaaa agaugugaag accaugcccu     1080

gguacgguaa aauugaccca uuuaucaacg agcugaaggc ccugggguug uauggcaaca     1140

ucaccagcgc gacugaaugg gcaagcgacg uaggcauuua cuaccucucc aaauucgggc     1200

uguauaguac gaaucgcaac gauaucgugc agagccugga gaaggccguc gacauguaca     1260

aguaugguaa aauugccuuu guggcaaugg agaggaucac cugggauuac gacggcauug     1320

gguccaaugg caagaaaguc gaucaugaca aguuccucga ugacgccgaa aaacacuauc     1380

ugccgaagac uuacaccuuu gauaacggua ccuucaucau ccgggcgggc gacaaaguga     1440

gcgaggaaaa gauuaagcgc uuguauuggg ccaguaggga ggugaaaucc caguuucauc     1500

ggguaguggg gaaugauaag gcacuggaag ucggcaacgc cgacgacgug cucacuauga     1560

aaaucuucaa uagccccgag gaguacaagu uuaacacgaa uauuaacggg gucuccaccg     1620

auaauggugg ccuguacauc gaaccacgcg ggacuuucua uaccuacgag aggacucccc     1680

aacagaguau uuuuagccug gaagaguugu uccggcacga guauacccau uaccuccagg     1740

caagguaucu gguggacggc cugugggguc aaggcccauu uuacgagaaa aaccgccuca     1800

cgugguucga ugaggggacc gccgaguucu uugccggcuc cacucggacc agcggggugc     1860

ugcccaggaa gaguaucuug ggcuaucugg caaaggacaa aguagaucac cgcuacuccc     1920

ucaagaaaac ucugaauagc gguuacgacg auuccgacug gauguucuau aacuacgggu     1980

uugccguggc gcacuaucug uacgaaaagg auaugccgac cuucauuaaa augaauaagg     2040

ccaucuugaa cacggacguc aagaguuaug augaaaucau uaaaaagcug agcgacgaug     2100

caaacaaaaa uaccgaguac cagaaccaua uccaggagcu cgccgacaag uaucagggcg     2160

ccgguauucc ccuggugucc gacgauuacc ucaaagacca cggcuacaag aaagcaagcg     2220

aagucuauag ugagaucucc aaggcggcca gccugacuaa uaccuccgug acugcagaaa     2280

agagccaaua cuuuaacacc uucacguugc gggggaccua uacuggcgag accaguaaag     2340

gggaauuuaa ggauugggac gagaugagca aaaagcugga uggcacucuc gagucccugg     2400

ccaaaaauag uuggagcggu uacaagaccc ugacggccua uuucaccaac uacaggguga     2460

cuuccgacaa uaagguacag uacgaugucg uguuucaugg gguguugacc gacaacgcag     2520

auauuagcaa uaacaaagcc ccaaucgcga aggucacugg ccccuccacc ggcgccgugg     2580

ggcgcaauau cgaguucagu gguaaagaca gcaaggauga agacggcaaa auuguguccu     2640

augacuggga uuuuggggac ggcgcaacga gucgggguaa gaacagcgua cacgccuaca     2700

agaaagccgg gaccuauaau gucacucuga aggugaccga ugacaaaggc gcaacugcca     2760

ccgaauccuu cacuaucgag auuaagaacg aagauaccac gaccccaauc acuaaagaga     2820

uggagcccaa ugacgauauu aaggaagcga acggcccaau cguggagggg gucaccguga     2880

aaggugaccu caacggcagc gaugacgccg auacuuucua cuuugacgua aaggaagaug     2940

gggacgugac caucgagcug ccguauagug gcuccagcaa uuucacgugg cucgucuaca     3000

aggaggguga cgaucagaac cacauugcau ccgggaucga caaaaauaac agcaaggugg     3060

gcaccuuuaa aaguacuaag ggcaggcauu auguguucau uuacaaacac gauuccgcca     3120

gcaauaucag uuacucccug aacauuaagg gguuggguaa ugaaaagcug aaagagaagg     3180

aaaacaauga cagcuccgau aaagcaaccg ucauccccaa cuuuaauacu accaugcagg     3240

gcagccugcu cggggacgau agucgggacu auuacagcuu cgaggugaag gaagagggcg     3300

agguaaacau ugaacuggau aaaaaggacg aguuuggugu gacguggacc uugcauccag     3360

aauccaauau caacgaucgc aucacuuaug ggcaagucga cggcaauaag gugaguaaca     3420

aagugaagcu gaggcccggc aaauacuauc uccuggucua caaguauagc ggguccggua     3480

acuacgagcu ccgggugaau aaaugaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  6879
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt7)

<400>  6879
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuga agaucauucu caauaggggc aaaaccauga      120

agcggaaaug ccugagcaag cgcuugaugc uggccaucac uauggcaacc auuuuuacgg      180

ugaacuccac ucuccccauc uacgccgcgg ucgacaaaaa uaacgccacc gcagccgugc      240

agaaugagag uaagagguau accguaagcu accugaagac uuugaacuau uacgaucugg      300

uggaccuccu ggucaaaacc gaaauugaga aucugccaga ucucuuccaa uauuccagug      360

acgcaaagga auuuuacggg aacaaaacgc ggaugagcuu caucauggau gagaucgguc      420

gcagggcccc gcaguauacu gaaauugacc acaagggcau ccccacccug guggaggugg      480

uccgggcggg guuuuacuug ggcuuccaua auaaagagcu gaacgaaauu aauaagcgcu      540

ccuuuaaaga gagggugauc ccaagcauuc ucgccaucca gaagaacccc aauuucaagc      600

uggguacuga aguacaggau aaaauugugu ccgcaaccgg gcuguuggcc ggcaacgaga      660

ccgccccacc cgaggucgug aauaacuuua cgccaauccu ccaagacugu aucaagaaca      720

uugaucggua cgcacuggac gaucugaaaa guaaggcccu cuucaaugug cuggcggccc      780

cgacuuauga caucaccgaa uacuugcgcg caacuaaaga gaagcccgaa aacaccccau      840

gguauggcaa gauugauggg uuuaucaaug agcugaaaaa gcucgcccug uacgguaaaa      900

uuaacgacaa uaacagcugg aucaucgaca auggcauuua ucacaucgca ccccugggga      960

aguugcauuc caacaauaaa auuggcaucg aaacccucac ugaggucaug aagguguacc     1020

cauaucugag caugcagcau cugcagagug ccgaucagau uaagaggcac uacgacucca     1080

aagaugccga ggguaacaag aucccccucg acaaauucaa gaaagaaggg aaggagaagu     1140

acugcccgaa aacguauacc uucgaugacg gcaagguaau cauuaaagcg ggcgcacggg     1200

uggaagagga aaaggucaaa cgccuguacu gggccagcaa ggaggugaau agucaauuuu     1260

ucagggugua ugggaucgau aaacccuugg aggaagguaa cccagacgau auucugacua     1320

uggucaucua caauaguccc gaggaauaua agcucaacag cgugcuguac ggcuaugaca     1380

ccaauaacgg gggcauguac auugagccag aagguaccuu uuucacuuac gagcgggagg     1440

cccaggaauc cacguauacc cuggaggaau uguuucgcca cgaguacacu cacuaucucc     1500

agggcaggua cgcaguaccc gggcaguggg gccggaccaa gcuguaugau aacgaccgcc     1560

ugaccuggua cgaggaaggg ggugccgaac ucuucgcggg cagcacuagg acgaguggga     1620

uccugccacg gaaauccauu gugagcaaua uccauaacac cacuaggaau aaccgcuaua     1680

aguugaguga caccguccac uccaaauacg gcgccagcuu ugaguucuac aauuaugcau     1740

guauguuuau ggauuacaug uauaacaagg acauggguau ccugaauaaa cucaacgauc     1800

uggccaagaa uaacgacgug gauggcuacg acaauuauau ucgggaucug agcuccaacu     1860

acgcauugaa ugacaaguau caagaucaua ugcaggagag gaucgacaac uacgaaaauc     1920

ugacuguccc guucguggcc gaugacuacc ucgugcgcca cgccuauaaa aaccccaacg     1980

agauuuacag ugagaucagc gaaguagcaa agcugaaaga ugccaagucc gaggugaaaa     2040

agagccagua uuuuaguacc uucacgcucc ggggguccua caccggcggg gcgagcaagg     2100

gcaaacugga agaccaaaag gccaugaaua aauuuauuga cgauuccuug aagaaacugg     2160

acacuuauag uuggagcggu uacaagaccc ucacugcaua cuucaccaac uauaaagucg     2220

auuccagcaa uagggugacg uacgacgucg uguuccacgg guaucugcca aacgagggcg     2280

auaguaaaaa uucccugccc uacgguaaga ucaacggcac cuauaagggg acugaaaagg     2340

agaaaaucaa guuuagcucc gagggcaguu ucgacccaga ugggaaaauu gugagcuacg     2400

aaugggacuu uggcgauggu aauaagucca acgaggaaaa ucccgagcau agcuaugaca     2460

agguagggac cuacacugug aaauugaagg ucaccgauga caaaggcgaa aguuccguga     2520

gcacgaccac ugccgagauc aaggaccugu ccgagaacaa acucccgguc auuuacaugc     2580

acgugccaaa gagcggcgcc cugaaucaga aggugguauu cuaugggaaa gguaccuacg     2640

aucccgacgg caguaucgca ggguaucagu gggauuuugg cgacgguagc gauuucucca     2700

gugaacagaa ccccagccau gucuacacua agaaagggga guauaccgug acgcuccgcg     2760

ugauggacuc cagcggccaa auguccgaaa agaccaugaa aauuaagauc acugauccag     2820

ucuaccccau cggcaccgag aaagagccaa auaacaguaa ggaaacugcg agcgggccga     2880

uugugcccgg uaucccagug uccggcacca uugagaauac uuccgaccag gauuauuuuu     2940

acuucgacgu aaucaccccc ggggaaguca agauugauau caacaaacug ggcuacggug     3000

gggccacgug ggugguguau gacgagaaca auaacgcagu cagcuacgcc accgaugacg     3060

gccagaauuu guccggcaag uuuaaagccg acaagccagg gcgguauuac auucaccugu     3120

auauguucaa cgguagcuac augcccuaua ggaucaauau cgaaggcagu guggggcggu     3180

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  6880
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt7)

<400>  6880
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaggaaau gccugagcaa gcggcucaug cuggccauca      120

ccauggcaac uauuuucacc gugaacucca cguugcccau cuacgccgcg gucgacaaaa      180

auaacgccac ugcagccgug cagaaugaga guaagcgcua uaccguaagc uaccugaaaa      240

cccucaacua uuacgaucug guggacuugc uggucaagac ugaaauugag aaucucccag      300

aucuguuuca auauuccagu gacgcaaagg aguucuacgg caacaaaacc aggaugagcu      360

uuaucaugga ugaaauuggg cggcgcgccc cgcaguauac ggaaaucgac cacaagggua      420

uccccacucu gguggaggug gucagggcgg gcuucuaccu cggguuucau aauaaagagc      480

ugaacgaaau uaauaagcgg uccuucaaag agcgcgugau cccaagcauu uuggccaucc      540

agaagaaccc caauuuuaaa cugggcaccg aaguacagga uaagauugug uccgcaacug      600

gucuccuggc cgggaacgag accgccccac ccgaggucgu gaauaacuuc accccaaucc      660

ugcaagacug uauuaagaau aucgauaggu acgcauugga cgaucucaaa aguaaggccc      720

uguuuaacgu gcuggcggcc ccgacguaug acaucacuga auaccuccgg gcaaccaaag      780

agaagcccga aaacacucca ugguauggca aaauugaugg cuucaucaau gagcugaaga      840

aguuggcccu guacgggaaa auuaacgaca auaacagcug gaucauugac aaugguaucu      900

aucacaucgc accccucggc aagcugcauu ccaacaauaa aauugggauc gaaacccuga      960

ccgaggucau gaagguguac ccauauuuga gcaugcagca ccuccagagu gccgaucaga     1020

uuaaacgcca uuacgacucc aaggaugccg agggcaacaa gaucccccug gacaaauuua     1080

agaaagaagg uaaggagaaa uacugcccga agacuuauac guucgaugac gggaagguaa     1140

uuaucaaagc gggcgcaagg guggaagagg aaaaggucaa acggcuguac ugggccagca     1200

aggaggugaa uagucaauuc uuucgcgugu auggcaucga uaaaccccuc gaggaaggga     1260

acccagacga uauucugacc auggucaucu acaauagucc cgaggaauau aaguugaaca     1320

gcgugcugua cgguuaugac acuaauaacg gcgggaugua cauugagcca gaaggcaccu     1380

ucuuuaccua cgagagggag gcccaggaau ccacuuauac gcucgaggaa cuguuccggc     1440

acgaguacac ccacuaucug cagggucgcu acgcaguacc cggccagugg gggaggacua     1500

aauuguauga uaaugaccgg cucaccuggu acgaggaagg cggggccgag cuguuugcgg     1560

guagcacccg cacuuccggc auccugccaa ggaaguccau ugugagcaac auccauaaca     1620

cgacccggaa uaacagguau aagcucagug acacugucca cuccaaauac ggggccagcu     1680

ucgaauuuua caauuaugca uguauguuca uggauuacau guauaacaag gacaugggca     1740

uucugaauaa auugaacgau cuggccaaga auaacgacgu ggaugguuac gacaauuaua     1800

uccgcgaucu cagcuccaac uacgcacuga augacaaaua ucaagaucau augcaggagc     1860

ggaucgacaa cuacgaaaau cugaccgucc cguuuguggc cgaugacuac uuggugaggc     1920

acgccuauaa gaaccccaau gagauuuaca gugagaucag cgaaguagca aagcugaaag     1980

augccaaguc cgaggugaaa aagagccagu auuucaguac uuuuacccuc cgcggcuccu     2040

acacgggcgg cgcgagcaaa gggaagcugg aagaccaaaa ggccaugaac aaauucauug     2100

acgauucccu caagaaacug gacaccuaua guuggagcgg cuacaagacu uugaccgcau     2160

acuuuacuaa cuauaaaguc gauuccagca aucgggugac cuacgacguc guguuccacg     2220

guuaucugcc aaacgagggg gauaguaaaa auucccuccc cuacggcaag aucaacggua     2280

cguauaaggg caccgaaaag gagaaaauua aguucagcuc cgaggggagu uuugacccag     2340

auggcaaaau cgugagcuac gaaugggacu ucggggaugg caauaagucc aacgaggaaa     2400

aucccgagca uagcuaugac aaaguaggua cuuacaccgu gaagcugaag gucacugaug     2460

acaaagggga aaguuccgug agcaccacga ccgccgagau caaggaccug uccgagaaca     2520

aauugccggu cauuuacaug cacgugccaa agagcggcgc ccugaaucag aaagugguau     2580

uuuauggcaa ggggacuuac gaucccgacg guaguaucgc aggcuaucag ugggauuucg     2640

gggacggcag cgauuuuucc agugaacaga accccagcca ugucuacacc aagaaaggug     2700

aguauacugu gacccucagg gugauggacu ccagcgggca aauguccgaa aagacgauga     2760

aaauuaagau caccgaucca gucuacccca uuggcacuga gaaagagcca aauaacagua     2820

aggaaaccgc gagcggcccg aucgugcccg ggaucccagu guccgguacu auugagaaua     2880

ccagugacca ggauuauuuc uacuuugacg uaaucacucc cggcgaaguc aaaauugaua     2940

ucaacaagcu gggguacggc ggugccaccu ggguggugua ugacgagaau aacaacgcag     3000

ucagcuacgc cacggaugac gggcagaauc ucuccggcaa guucaaagcc gacaagccag     3060

gccgcuauua cauucaccug uauauguuua acgggagcua caugcccuau cggaucaaua     3120

uugaagguag uguggggagg ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  6881
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt7)

<400>  6881
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucucca      120

gugccuacag cguccagaac gaguccaaaa gguauacugu gaguuacuug aagacccuga      180

auuauuacga ccucguagau cuguugguga aaacggaaau ugagaaccug cccgaccucu      240

uucaauauag cuccgaugca aaggaguucu acggcaauaa aacucggaug agcuuuauca      300

uggacgaaau ugggcgcagg gccccacagu auaccgaaau cgaucacaag gguauuccga      360

cccuggucga gguggugcgg gcgggcuucu accugggguu ucauaacaag gagcucaaug      420

aaaucaacaa acgcuccuuc aaggagaggg ucauccccag uauucuggcc auccagaaaa      480

auccaaacuu uaaguugggc acugaagugc aggacaaaau uguaagcgca accggucugc      540

ucgccgggaa ugagacggca cccccagagg uggucaacaa uuucacuccc auccugcaag      600

auugcauuaa gaacaucgac cgguacgccc uggaugacuu gaaauccaag gcgcucuuua      660

augugcuggc cgcaccaacc uaugauauua cugaauaccu gcgcgccacc aaggagaaac      720

cggaaaacac ccccugguau ggcaagaucg acggcuucau caaugagcuc aaaaagcugg      780

ccuuguacgg gaaaauuaac gauaacaaua gcuggaucau ugacaacggu aucuaucaca      840

uugcaccacu gggcaagcuc cauaguaaua acaagaucgg gaucgaaacg cugacugagg      900

ugaugaaagu cuaccccuau cuguccaugc agcacuugca gagcgccgac cagauuaaga      960

ggcauuacga uuccaaagac gcggagggca auaagauccc acucgauaaa uucaagaagg     1020

aagguaaaga gaaguacugu cccaaaaccu auacuuuuga cgaugggaag gugauuauca     1080

aagccggcgc acggguagaa gaggaaaagg ugaagcgccu guacugggcc aguaaagagg     1140

ucaacagcca auucuuuagg guguauggca uugacaagcc gcuggaggaa gggaaucccg     1200

augacauccu caccauggug aucuacaacu ccccagagga auauaaacug aauagcgucu     1260

uguacgguua ugauaccaac aauggcggga uguacauuga gcccgaaggc acuuucuuua     1320

cguacgagcg ggaggcacag gaaaguaccu auacucugga ggaacucuuc cgccacgagu     1380

acacccacua ucugcagggu agguacgccg ugccaggcca gugggggcgg accaagcugu     1440

augacaacga ucgcuugacu ugguacgagg aaggcggggc cgagcucuuu gcggguucca     1500

cgaggaccag cggcauccug ccccggaaaa guauuguauc caauauccau aacacuaccc     1560

gcaauaacag guauaagcug agcgacaccg ugcacagcaa auacggggca uccuucgaau     1620

uuuacaacua ugccugcaug uucauggacu acauguauaa uaaggauaug ggcauucuca     1680

acaagcugaa ugacuuggcc aaaaacaaug augucgacgg uuacgauaac uauauccggg     1740

accugaguag caauuacgca cucaacgaua aguaucaaga ccauaugcag gagaggauug     1800

auaauuacga aaaccugacu gugccauuug ucgccgacga uuaccuggug cgccacgcgu     1860

auaaaaaucc gaacgagauc uacuccgaga ucagcgaagu ggccaaguug aaagacgcaa     1920

agagugaggu aaagaaaucc caguauuuca gcacguuuac ccugcggggc uccuacacug     1980

ggggcgccag uaaggggaaa cucgaagauc aaaaggcaau gaauaaauuc auugacgaca     2040

gccugaagaa gcucgauacc uauuccugga gcggcuacaa aacucugacc gccuacuuca     2100

cgaacuauaa gguggacagu uccaauaggg ucaccuacga uguggucuuu cacgguuauu     2160

ugcccaacga gggggacagc aaaaacuccc ugccauacgg caagaucaau gguacuuaua     2220

aaggcaccga aaaggagaaa auuaaguuca guagcgaggg guccuuugau cccgacggca     2280

agaucgugag cuacgaaugg gauuucgggg acggcaacaa aaguaaugag gaaaacccag     2340

agcauuccua ugauaaggug gguacuuaca ccguaaaacu caaggugacg gacgauaaag     2400

gggaaagcuc cgucagcacc acuaccgccg agauuaagga ccugagugag aauaagcugc     2460

ccgugaucua caugcacguc ccgaaaagcg gcgcauugaa ccagaaggug guguuuuaug     2520

gcaaagggac uuacgaccca gaugguucca ucgccggcua ucagugggac uucggggaug     2580

gcagugacuu uagcuccgaa cagaauccca gccauguaua caccaagaaa ggugaguaua     2640

cggucacccu gcgcgugaug gauuccagug ggcaaaugag cgaaaagacu augaagauua     2700

aaaucaccga ccccguguac ccaauuggca cugagaagga gcccaacaau uccaaagaaa     2760

ccgcgagugg cccaaucguc ccggggauuc ccgugagcgg uacgaucgag aacaccuccg     2820

aucaggacua uuucuacuuu gaugugauca cuccaggcga aguaaagauu gacaucaaua     2880

aacucgggua cggcggugcc accugggucg uguaugauga gaacaauaac gcagugagcu     2940

acgccacuga cgaugggcag aaucugagug gcaaguucaa agccgacaag cccggccggu     3000

auuacauuca ccucuauaug uuuaacgggu ccuacaugcc auauaggauc aacauugaag     3060

guagcgucgg ccgcugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6882
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt7)

<400>  6882
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcucuuu cuguucucca      120

gugccuacag caugaaaagg aagugcuugu ccaaacggcu gaugcucgca auuacuaugg      180

ccaccaucuu uacggucaac aguacucugc ccauuuaugc ggccguggac aagaauaacg      240

caaccgccgc acgcaggcgg cgcaaaaggg uacagaauga gagcaagcgg uacaccgugu      300

ccuauuugaa gacucugaac uacuaugauc ucgucgaccu gcuggugaaa accgaaaucg      360

agaaucuccc agaucuguuc caauacagcu ccgacgccaa ggaauuuuau ggcaacaaaa      420

cgcgcaugag uuucauuaug gaugagaucg ggaggcgggc gccgcaguac acugaaaucg      480

accacaaggg uauucccacc uugguggagg ucgugcgcgc cggcuuuuac cugggguucc      540

auaauaaaga gcucaacgaa aucaauaaga ggagcuuuaa agagcgggua auuccaucca      600

uccuggcaau ucagaagaac cccaauuuca agcugggcac ugaagugcag gauaaaaucg      660

ucagcgccac cgguuugcuc gccgggaacg agaccgcacc acccgaggug gugaauaacu      720

uuacgccaau ucugcaagac uguaucaaga auaucgaucg cuaugcccug gacgaucuca      780

aaaguaaggc gcuguucaac gucuuggccg caccgacuua cgacauuacc gaauaucuga      840

gggccacuaa agagaagccc gaaaacaccc caugguacgg caagaucgau ggcuucauua      900

augagcucaa aaagcuggca cuguauggga aaaucaacga caauaacucc uggauuaucg      960

acaaugguau cuaccacauu gcccccuugg gcaagcucca uagcaacaau aaaaucggga     1020

uugaaacccu gacugaggug augaagguau auccauaccu guccaugcag caccuccaga     1080

gugccgauca gaucaagcgg cauuacgaca gcaaagaugc ggagggcaac aagauucccc     1140

uggacaaauu uaagaaagaa gguaaggaga aguauugccc gaaaacguac accuucgaug     1200

acgggaaggu gaucaucaaa gcaggcgccc gcgucgaaga ggaaaaggug aaaagguugu     1260

auugggccuc caaggaggug aauagccaau uuuuccgggu cuacggcauu gauaaacccc     1320

uggaggaagg gaacccagac gauauccuca cuauggugau uuauaauagu cccgaggaau     1380

acaagcugaa cuccguacug uaugguuacg acaccaauaa cggcgggaug uacaucgagc     1440

cagaaggcac cuuuuucacu uaugagcgcg aggcacagga aagcacguac accuuggagg     1500

aacucuuuag gcacgaguau acucacuacc ugcagggucg guaugccgug cccggccagu     1560

gggggaggac caagcuguac gauaaugacc gccucaccug guaugaggaa ggcggggcgg     1620

agcuguucgc cgguaguacu cggacguccg gcauuuugcc aaggaaaagc aucgucagca     1680

acauucauaa caccacucgc aauaaccggu acaagcuguc cgacaccgug cacaguaaau     1740

acggggcgag cuuugaguuc uauaauuacg ccuguauguu uauggauuau auguacaaca     1800

aggacauggg cauccucaau aaacugaacg aucuggcaaa gaauaacgac gucgaugguu     1860

augacaauua caucagggau uuguccagca acuaugcccu gaaugacaag uaccaagauc     1920

auaugcagga acgcauugac aacuacgaaa aucucacugu gccguucgug gccgaugacu     1980

aucugguacg gcacgcauac aaaaacccca augagaucua uagugagauu uccgaagugg     2040

ccaagcucaa agaugcaaag agcgagguca aaaaguccca guacuuuagu accuucacgc     2100

ugaggggcag cuauaccggg ggcgccucca aggggaaauu ggaagaccaa aaggcaauga     2160

acaaauucau cgacgauagc cugaagaaac ucgacacuua caguuggucc ggcuacaaga     2220

cccugacugc cuauuuuacc aacuacaaag uggauagcuc caaucggguc acguaugacg     2280

ugguguucca cgguuaccug ccaaacgagg gggauaguaa gaauagcuug cccuauggca     2340

agauuaacgg uaccuacaaa ggcacugaaa aggagaaaau caaguuuucc agcgagggga     2400

guuucgaccc agauggcaaa aucguauccu augaauggga cuuuggggau ggcaauaaga     2460

gcaacgagga aaaucccgag cauuccuacg acaagguggg uaccuacacu gucaaacuga     2520

aggugaccga ugacaaaggg gaaagcagug ucagcacgac cacugccgag auuaaggacc     2580

ucuccgagaa caaacugccg gugaucuaua ugcacgugcc aaagaguggc gcacucaauc     2640

agaagguagu cuucuacggc aaagggaccu augaucccga cgguagcauu gcgggcuacc     2700

agugggauuu uggggacggc uccgauuuca gcuccgaaca gaaccccagu cauguguaua     2760

cuaagaaagg ugaguacacc gugacgcugc gcgucaugga cagcuccggg caaaugagug     2820

aaaagaccau gaaaaucaag auuacugauc caguguaucc caucggcacc gagaaagagc     2880

caaauaacag caaggaaacu gccuccggcc cgaucgugcc cgggauucca guaagcggua     2940

ccaucgagaa uaccagugac caggauuacu uuuacuucga cgucauuacu cccggcgaag     3000

ugaagaucga uauuaacaaa uugggguaug gcggugcaac gugggugguc uacgacgaga     3060

auaacaacgc cguguccuau gccaccgaug acgggcagaa ucugagcggc aaguuuaaag     3120

cagacaagcc aggcagguac uauauccacc uguacauguu caacgggucc uauaugcccu     3180

accggauuaa uaucgaaggu agcguaggcc gcugaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  6883
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt7)

<400>  6883
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcagccu      120

uugcgaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc agcuaugagg      180

ugcugacucc ccucaagugg uaccagucca ucaggccacc cuauccaagu uacggguaug      240

aaccgauggg cgguuggcug caccaucaaa uuauccccgu cuugagccag cagcacccac      300

ccacccauac gcugcagcca caccaccaua uucccguggu accggcccaa cagcccguga      360

ucccacagca gcccaugaug ccaguccccg ggcaacacuc caugacucca auccagcauc      420

accagccgaa ucugccccca cccgcacagc aaccauacca gccccagccg gugcaaccac      480

agccccacca gcccaugcag ccacaacccc cagugcaucc gaugcagccc cucccacccc      540

agccaccccu gccgccaaug uuucccaugc agccacugcc cccgaugcuc cccgacuuga      600

cccuggaggc cuggccaagu accgauaaaa cuaagcggga agaggucgac ugaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  6884
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt7)

<400>  6884
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacc ccacugaagu gguaccaguc cauuaggcca cccuauccca      180

guuacgguua ugaaccgaug ggcggguggu gaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  6885
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt7)

<400>  6885
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacu ccccugaagu gguaccaguc cauuaggcca cccccaaugu      180

ugccggaccu gacccucgaa gccuggccca guaccgauaa aacgaagcgg gaggaagucg      240

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  6886
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt7)

<400>  6886
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cacccaggac ccugguccuc cuguugagcg      120

gcgcccuggc gcucacucag accugggcca ugccacugcc gccccaccca gggcaucccg      180

guuacaucaa cuucuccuau gagguguuga cgccacugaa gugguaccaa aguauucggc      240

ccccauaucc gagcuacggc uaugaaccca ugggcgggug gugaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  6887
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt7)

<400>  6887
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cacccaggac ccugguccuc cuguugagcg      120

gcgcccuggc gcucacucag accugggcca ugccacugcc gccccaccca gggcaucccg      180

guuacaucaa cuucuccuau gagguguuga cgccacugaa gugguaccaa aguauucggc      240

ccccaccgau gcuccccgac cugacucugg aagcauggcc aagcaccgau aaaaccaagc      300

gcgaggaagu agacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  6888
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt7)

<400>  6888
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccucgug ggggcagccu      120

uugcgaugcc ccugccaccg caccccgguc auccaggcua cauuaacuuc agcuaugagg      180

ucuugacucc ccugaagugg uaccagucca ugaucaggcc acccuauagu agcuacgggu      240

augaaccaau gggcgguugg cuccaccauc aaauuauccc ggugguaucc cagcagcacc      300

cccugaccca uacguugcag agucaccacc auauuccagu gguccccgcc caacagccac      360

gggugcgcca gcaggcacug augcccgugc cggggcaaca gagcaugacu cccacccagc      420

accaucagcc aaaucucccc cugccagccc aacagcccuu ucagccacaa ccgguccagc      480

cccagccaca ccagcccaug caaccacagc ccccggugca gccaaugcag ccccugcucc      540

cccaaccacc ccugccaccg auguuccccu ugaggccacu gcccccaauc cuccccgacc      600

ugcaccugga ggcauggccg gccaccgaua aaacuaagca ggaagaggua gacugaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  6889
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt7)

<400>  6889
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacc ccacugaagu gguaccaguc caugauuagg ccacccuaua      180

guagcuacgg uuaugaaccc augggcgggu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6890
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt7)

<400>  6890
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacu ccccugaagu gguaccaguc caugauuagg ccacccccaa      180

ucuugccgga ccugcaccuc gaagccuggc ccgcaaccga uaaaaccaag caagaggaag      240

ucgacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6891
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt7)

<400>  6891
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cacccaggac ccugguccuc cuguugagcg      120

gcgcccuggc gcucacucag accugggcca ugccacugcc gccccaccca gggcaucccg      180

guuacaucaa cuucuccuau gagguguuga cgccacugaa gugguaccaa aguaugauuc      240

ggcccccaua uagcuccuac ggcuaugaac cgaugggcgg guggugagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6892
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt7)

<400>  6892
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cacccaggac ccugguccuc cuguugagcg      120

gcgcccuggc gcucacucag accugggcca ugccacugcc gccccaccca gggcaucccg      180

guuacaucaa cuucuccuau gagguguuga cgccacugaa gugguaccaa aguaugauuc      240

ggcccccacc gauccucccc gaccugcacc uggaagcaug gccagccacu gauaaaacca      300

agcaggagga aguagacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6893
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt7)

<400>  6893
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcagccu      120

uuagcaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc uccuaugagg      180

ugcugacucc ccucaagugg uaccagaaua ugaucaggca cccauauacc aguuacgggu      240

augaacccau gggcgguugg cugcaucacc aaauuauccc agucgugagc cagcagacgc      300

cgcaguccca ugcguugcaa ccccaccacc auauuccaau gguacccgcc cagcagccag      360

ggauccccca gcaaccgaug augccccugc caggccagca caguaugacu cccacccagc      420

aucaccagcc aaaccucccc cugccagcac aacagccguu ucagccccaa ccagugcagc      480

cccagccaca ccagccccug caaccgcaga gcccaaugca ucccauccag ccccuccugc      540

cacagccccc auugccgccc auguucucca ugcaaagccu gcucccagac cugccccugg      600

aggccuggcc agcaaccgau aaaacuaagc gggaagaggu cgacugagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6894
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt7)

<400>  6894
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacu ccccugaagu gguaccagaa uaugauuagg cacccauaua      180

ccuccuacgg uuaugaaccc augggcgggu ggugaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6895
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt7)

<400>  6895
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacu ccccugaagu gguaccagaa uaugauuagg cacccauccu      180

ugcugcccga ccucccacug gaagccuggc cggcaaccga uaaaaccaag cgggaggaag      240

ucgacugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6896
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt7)

<400>  6896
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cacccaggac ucugguccuc cuguugagcg      120

gcgcccuggc gcucacucag accugggcca ugccacugcc gccccaccca gggcaucccg      180

guuacaucaa cuucuccuau gagguguuga cgccacugaa gugguaccaa aauaugauuc      240

ggcaccccua uaccaguuac ggcuaugaac caaugggcgg guggugagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6897
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt7)

<400>  6897
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgugaugg cacccaggac ccugguccuc cuguugagcg      120

gcgcccuggc gcucacucag accugggcca ugccacugcc gccccaccca gggcaucccg      180

guuacaucaa cuucuccuau gagguguuga cgccacugaa gugguaccaa aauaugauuc      240

ggcaccccag ucuccugcca gaccugccgc ucgaagcaug gcccgccacu gauaaaacca      300

agcgcgagga aguagacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6898
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt7)

<400>  6898
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcagccu      120

uuagcaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc uccuauauca      180

ggcaccccua caccaguuau ggguacgagc caaugggcgg uuggcugcau caccagauua      240

uccccguggu cagccaacag acuccacagu cccaugcgcu ccagccgcac caccauauuc      300

ccauggugcc agcccaacag cccgggaucc cacagcagcc caugaugccg cugcccggcc      360

aacacaguau gacgccaacu cagcaucacc agcccaauuu gccacugccc gcacagcaac      420

cauuucagcc gcagcccgua caaccacagc cccaccagcc acuccagccc caaagcccga      480

ugcauccaau ccagccccug cugccccagc caccccuccc accgauguuc uccaugcaga      540

gccuguugcc cgaccugcca cucgaagccu ggcccgcaac cgauaagacc aaacgggagg      600

aaguggacug aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  6899
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt7)

<400>  6899
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuuugc cugccugcuc ggggcaagcc      120

uggccaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc uccuaugagg      180

ugcugacucc ccucaagugg uaccagaaua ugaucaggca cccauauacc aguuacgggu      240

augaacccau gggcgguugg cugcaucacc aaauuauccc agucgugagc cagcagacgc      300

cgcaguccca ugcguugcaa ccccaccacc auauuccaau gguacccgcc cagcagccag      360

ggauccccca gcaaccgaug augccccugc caggccagca caguaugacu cccacccagc      420

aucaccagcc aaaccucccc cugccagcac aacagccguu ucagccccaa ccagugcagc      480

cccagccaca ccagccccug caaccgcaga gcccaaugca ucccauccag ccccuccugc      540

cacagccccc auugccgccc auguucucca ugcaaagccu gcucccagac cugccccugg      600

aggccuggcc agcaaccgau aaaacuaagc gggaagaggu cgacugagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6900
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt7)

<400>  6900
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcagccu      120

uuagcaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc uccuaugagg      180

ugcugacucc ccucaagugg uaccagaaua ugaucaggca cccaagucug uugcccgacc      240

ugccacucga agcguggccg gccaccgaua aaacgaagcg ggaggaaguc gacugaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  6901
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt7)

<400>  6901
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcagccu      120

uuagcaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc uccuaugagg      180

accuguaccu cgaagcgauc aggauugauc ggacugccuu ugugcugacc cccuugaagu      240

gguaucagaa uaugauccgc cacccauaca cgaguuaugg guacgagccc augggcgguu      300

ggcugcauca ccaaauuauc ccagucguga gccagcagac uccgcagucc caugcacucc      360

aaccccacca ccauauccca augguacccg cccagcagcc agggauuccc cagcaaccga      420

ugaugccccu gccaggccag cacaguauga cccccaccca gcaucaccag ccaaaccugc      480

cccucccagc acaacagccg uuccagcccc aaccagugca gccccagcca caccagcccc      540

ugcaaccgca gagcccaaug caucccaucc agcccuugcu gccacagccc ccacucccgc      600

ccauguuuuc caugcaaagc cugcugccag acuugccccu cgaagccugg ccagcgacug      660

auaaaaccaa gagggaggaa gucgacugag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  6902
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt7)

<400>  6902
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuguucgc cugccuccug ggggcagccu      120

uuagcaugcc cuugccaccg caccccgguc auccaggcua cauuaacuuc uccuaugagg      180

ugcugacucc ccucaagugg uaccagaaua ugaucaggca cccaacgccc caaagucaug      240

cgcugcagcc acaccaucac auuccgaugg uccccgccca gcagccaggg aucccccaac      300

agccaaugau gcccuugccg ggccagcaca gcaugacccc cacucagcau caccaaccaa      360

accugccccu cccagcacag cagcccuuuc agccacaacc ggugcagccc cagccacauc      420

aaccccugca gccacagucc cccaugcacc cgauucagcc acugcucccc caacccccac      480

ugcccccaau guucaguaug cagagcuugc ugccggaccu cccccuggaa gccuggccag      540

caaccgauaa aaccaagcgg gaggaaguag acugaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  6903
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt7)

<400>  6903
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugccac cgcaccccgg ccauccaggg uacaucaacu      120

ucagcuauga ggugcucacu ccccugaagu gguaccagaa uaugauuagg cacccauaua      180

ccuccuacgg uuaugaaccc augggcgggu gguugcauca ccaaaucauu ccagucguga      240

gucagcagac cccgcagagc caugcccugc aaccccacca ccauauccca augguacccg      300

cacagcagcc aggcauuccc cagcaaccga ugaugccccu cccaggucag cacuccauga      360

cgcccacuca gcaucaccag ccaaaccugc ccuugccagc ccaacagccg uuucagcccc      420

aaccagugca gccccagcca caccagcccc ugcaaccgca gaguccaaug caucccaucc      480

agccccuccu gccacagccc ccacugccgc ccauguucag caugcaaucc cuccugccag      540

acuugccccu ggaggcgugg ccagccaccg auaaaaccaa gcgggaagag gucgacugag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  6904
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt7)

<400>  6904
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggcgugg ccaggcugcc acuccuguug gggcugcucc      120

uguugccgcg gcccggucgc ccacuggacc ucgcagauua caccuaugac cuggccgagg      180

aagaugacag cgagccccug aacuacaagg auccaugcaa agcggccgca uuccucggcg      240

acaucgcccu ggaugaagag gacuugaggg cauuucaggu ccaacaggcc guggaucugc      300

ggcgccacac ugcgaggaag uccaguauua aagccgcagu acccgggaau accagcacgc      360

cauccuguca gaguacuaac ggccagccgc aacggggugc cugcgggcgc uggaggggcc      420

ggagccgcuc caggcgggcc gcaaccagcc gccccgaaag gguguggcca gacggcguca      480

uccccuucgu gauugggggu aauuuuaccg gcucccagcg ggccguguuc cgccaggcga      540

ugaggcauug ggagaagcac acuuguguca ccuuucucga gcggacggau gaagacaguu      600

auaucguguu cacuuaccgc ccaugcgggu guugcagcua uguaggcagg cggggugggg      660

gcccccaggc cauuuccauc ggcaaaaacu gugauaaguu ugggaucgug guccaugagc      720

ugggucacgu ggugggcuuc uggcaugaac acaccaggcc ggaccgcgac cggcacguca      780

gcauugugag ggagaauauc caacccgggc aggaguacaa cuuucugaag auggaaccac      840

aggagguaga aaguuugggc gagacuuaug auuucgacuc cauuaugcau uacgcacgca      900

auaccuuuag ccgggguauc uuccucgaua ccauugugcc caaauacgaa gucaacggcg      960

ugaagccacc caucgggcag aggacgcgcc uguccaaagg cgacauugcc caagcacgga     1020

agcuguauaa augcccagcc uguggggaga cucuccagga uaguaccggu aauuucagcu     1080

ccccggagua ccccaacggc uauagcgccc acaugcauug cguguggagg aucaguguca     1140

cuccagggga aaagaucauu cugaauuuua ccuccuugga ccuguaccgg agccgccucu     1200

gcugguauga uuacguggag guaagggacg gcuucuggcg gaaagcgccc cugcgcggua     1260

gguuuugugg caguaagcug ccagaaccca ucguguccac cgauagccgg uugugggucg     1320

aguuccgcag cuccaguaac ugggugggga agggcuuuuu cgcagucuau gaagccauuu     1380

gcgggggcga cgugaaaaag gauuacgguc acauccagag cccgaauuac ccagacgacu     1440

auaggcccuc caaagugugu auuuggcgga uccaaguaag cgagggguuu cacgugggcc     1500

ucacuuucca gaguuuugag aucgaaaggc augauuccug cgccuacgac uaucuggagg     1560

uccgcgaugg ucacagcgaa uccaguacgc ugauuggccg guacuguggg uaugagaagc     1620

ccgacgauau caaaagcacc uccagcaggc ucuggcugaa guucgugagu gacggcucca     1680

uuaacaaggc aggguuugcc gucaauuucu uuaaagaagu ggaugagugc agccgcccaa     1740

accggggcgg uugugagcag aggugcuuga acacucuggg guccuacaag uguaguugcg     1800

accccggcua ugaacucgcg ccagauaaac gccggugcga ggccgcaugu ggcggguucc     1860

ugaccaagcu gaaugguagc aucaccuccc cgggcuggcc caaagaauac ccacccaaca     1920

agaauugcau uuggcaguug guggccccaa cucaauacag gaucagccuc caguucgacu     1980

uuuucgagac ggaggggaac gauguaugua aguaugacuu uguggaaguc cgcaguggcc     2040

ugaccgcaga uuccaaacug caugguaagu ucugcgggag cgagaaaccc gaagugauca     2100

cuucccagua caauaacaug cgggucgagu uuaagagcga caauaccgug aguaaaaagg     2160

gcuucaaggc ccacuuuuuc agcgacaaag augaauguuc caaggacaac ggcgggugcc     2220

agcaagauug ugugaauacc uuugguaguu augagugcca guguaggagc ggcuucguac     2280

uccaugacaa caaacacgau ugcaaggagg ccggguguga ccacaaaguc acuuccacga     2340

gcggcaccau uacuuccccg aauuggccag auaaguaccc caguaaaaag gaaugcaccu     2400

gggcaaucag cuccacucca ggucaucgcg ugaagcugac cuuuauggag auggacauug     2460

aaagucagcc cgagugcgcc uaugaucacu uggaaguguu cgacgggcgg gaugcgaaag     2520

ccccgguccu gggcagguuc uguggcagca agaaacccga gccagugcuc gcaacggggu     2580

cccgcauguu ucugcgguuc uacagcgaca acagugugca gaggaagggu uuucaagccu     2640

cccaugccac cgagugcggc gggcagguac gcgcagacgu caaaacuaag gaucuguaua     2700

gccacgcgca guucggcgac aauaacuacc ccgguggggu ggauugugaa ugggugaucg     2760

ucgccgagga aggcuacggc guggaguugg uauuucagac cuucgaagug gaggaggaaa     2820

cugacugcgg guaugauuac auggagcugu uugacgguua ugauuccacc gcaccaaggc     2880

ucggccggua cugugggagc ggucccccag aagaggucua uagugccggc gacuccgugc     2940

uggugaaguu ccacagcgau gacacgauua ccaaaaaggg cuuucaucuc agguacacca     3000

guacuaaauu ccaagauacu cugcacuccc gcaagugagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  6905
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt7)

<400>  6905
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggccggca ccaggugccu gcucgcacug uugcugcccc      120

agguccuccu ggguggggcc gcgggcuugg ugccagagcu ggggcggcgc aaguucgccg      180

cagccagcuc cggcaggccg aguagccaac ccuccgacga aguacucagu gaguuugaac      240

ugcggcugcu cagcauguuc ggucugaaac agcgcccaac ucccuccagg gaugcagugg      300

ucccacccua cauguuggac cuguaucggc gccacagcgg gcagccaggc uccccggccc      360

ccgaucauag gcucgagcgg gcggccaguc gcgcaaacac cgugaggagc uuucaccaug      420

aagagucccu ggaggaacug ccagagacga gcggcaagac uacccggcgc uucuuuuuca      480

auuugaguuc cauccccacc gaagaguuua uuacuagcgc cgagcuccag guguucaggg      540

aacaaaugca ggacgcccug gggaacaauu ccaguuuuca ccaucggauc aacauuuacg      600

agaucauuaa accagcaacc gccaauagca aguuccccgu cacgcgccug cucgauacua      660

ggcuggugaa ccagaaugcg ucccgguggg aauccuuuga cguaaccccg gccgugaugc      720

gcuggacugc acagggucac gccaaccacg gcuucgucgu ggagguggca cauuuggaag      780

agaaacaagg ggucaguaag aggcacgugc ggaucuccag gagccugcau caggaugagc      840

acaguugguc ccagauccgc ccccuccugg uaaccuucgg ccacgacggu aaggggcauc      900

cacugcacaa acgggaaaag aggcaggcca aacauaagca acgcaaacgg cucaagagca      960

gcuguaaaag gcaccccuug uauguggauu uuuccgacgu cggcuggaau gauuggauug     1020

uggccccacc cggcuaccau gcguucuauu gccacgggga guguccauuu ccgcuggcag     1080

accaccugaa caguaccaau caugccaucg ugcagacgcu cgucaacagc gugaauagca     1140

agauucccaa ggccugcugu guaccaacug aacugagcgc aaucaguaug uuguaccugg     1200

augagaacga aaaagugguc cucaagaauu aucaggacau gguggucgag gguugcggcu     1260

gucgcugagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  6906
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt7)

<400>  6906
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auccccggca acaggaugcu gauggugguc cuccugugcc      120

agguguugcu cgggggugcc agccacgcau cccugauucc agagaccggc aagaaaaagg      180

uagccgaaau ccaagggcau gcgggcgguc ggcgcagugg gcagagccac gagcuguuga      240

gggacuucga agccacucug cuccagaugu uuggccugcg gcgcaggccg cagcccucca      300

aaagugcagu gauuccagau uacaugcggg accuguaucg ccuccaaagc ggcgaggaag      360

aggaggaaca gauccauucc accgggcugg aguaccccga aaggccagcc agccgggcaa      420

auacgguccg cuccuuccac caugaggagc acuuggaaaa cauucccggu accagugaga      480

auagcgccuu uagguuccug uuuaaccucu ccagcauccc agaaaaugag gugaucaguu      540

ccgcggaacu gcggcuguuc cgcgaacagg uggaucaggg cccggacugg gagagggggu      600

uucaccggau uaacaucuau gaggucauga agcccccagc cgagguggua cccggccauu      660

ugauuacucg ccuccuggau accaggcugg ugcaccauaa ugucacucgg ugggaaaccu      720

ucgacgugag cccagcagug cuccgcugga cgagggagaa acaacccaac uacggucugg      780

ccaucgaagu cacucacuug caccagaccc ggacucauca ggggcagcac gugaggauuu      840

cccgcagucu gccgcaaggc agcggcaauu gggcccagcu ccggccccug cugguaaccu      900

uugggcauga ugguaggggc cacgcauuga cccgccggag gcgcgccaag cgguccccaa      960

agcaucacag ccagagggcg cggaaaaaga acaaaaauug ucgcaggcac agucucuaug     1020

uggacuucuc cgaugucggg uggaacgacu ggaucguggc acccccaggc uaccaagccu     1080

uuuauugcca uggugauugu cccuucccac uggccgacca ccugaauagc acgaaccaug     1140

caauugugca gacucucguc aauaguguga acuccagcau cccgaaggcc ugcuguguac     1200

ccaccgagcu gagcgccauc uccauguugu accuggauga guacgacaaa gugguccuca     1260

agaacuauca ggaaauggug gucgagggcu gcgggugucg gugaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  6907
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt7)

<400>  6907
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggccugg ggaggcgggc ccaguggcuc ugcugguggu      120

ggggucuguu guguagcugc uguggcccac cgccccugcg cccaccccuc ccagcagccg      180

cggccgcagc cgcagggggc caacuguugg gugacggggg cucccccggc aggaccgagc      240

agccaccgcc caguccacag agcuccagug gguuccugua ccggcgccuc aagacucagg      300

agaaaaggga aaugcaaaag gaaauccuga gcgugcuggg ucucccccac cggccacgcc      360

cccugcaugg cuugcagcag ccgcagcccc cagcccugag gcaacaggag gaacagcagc      420

aacagcagca acucccccgc ggggagccac ccccaggccg gcugaaaucc gcgccgcugu      480

uuauguugga ucucuauaac gcccugagcg cagacaauga ugaggacggu gccuccgaag      540

gggagaggca gcagaguugg ccccacgaag ccgcaagcuc cagccagcgg cgccaaccac      600

ccccaggcgc cgcgcauccc cugaacagga agagucuccu ggccccgggc uccgggagcg      660

guggcgcauc cccauugacc agugcccagg auagcgcauu ccugaaugac gccgauaugg      720

ucauguccuu ugugaaccuc guagaguacg acaaagaguu cagcccccgg cagcgccacc      780

auaaggaauu uaaguucaau cugagucaga uucccgaggg ggaagugguc acggccgcgg      840

aguuuaggau cuauaaagau ugcgugaugg gcuccuucaa gaaccaaacu uuucugauua      900

gcaucuacca gguguugcag gaacaccagc accgggacag ugaucucuuc cugcuggaca      960

cccgcgucgu gugggcaucc gaggaggguu ggcucgaauu ugauauuacc gccacuagca     1020

aucugugggu agugacccca caacauaaca ugggcuugca gcugagcguc gugacgaggg     1080

acggggugca cguccauccc cgggccgcag gccucguggg gagggacggu ccauaugaua     1140

aacagccguu caugguagcc uucuuuaagg uguccgaggu ccacgugcgc acuacccgga     1200

gugcgagcuc caggcgccgg cagcaaagca ggaaucgcag uacucagucc caggacgugg     1260

cccgggucag cuccgcaagu gauuacaaca gcuccgaacu gaaaaccgcc uguaggaagc     1320

acgagcugua ugugagcuuc caagacuugg gcuggcagga uuggaucauc gcacccaaag     1380

gguacgccgc caauuacugc gacggcgaau guaguuuucc acucaacgca cauaugaaug     1440

ccaccaacca cgcgauugua cagacgcugg ugcaucugau gaaucccgag uaugucccaa     1500

agcccugcug ugccccgacu aagcucaacg caaucuccgu gcuguacuuc gaugacaaca     1560

gcaaugucau uuugaaaaag uaucggaaca ugguggugcg cgccugcggu ugccacugag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  6908
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt7)

<400>  6908
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugagga gccugcgggc cgcagcgccc cauuccuucg      120

ucgcccucug ggccccacug uuuuugcugc gcagugcacu cgccgacuuc agccuggaua      180

acgaggugca cuccaguuuu auccauaggc gguugcgcag ccaggaaagg cgggagaugc      240

aacgcgaaau ucuguccauc cucggccugc cgcacaggcc ccggccacau cugcagggga      300

agcacaauag cgcacccaug uucaugcucg accuguacaa cgccauggcg guagaggaag      360

guggcgggcc aggcggucag ggguuuuccu aucccuacaa agccguguuc aguacccagg      420

gcccaccguu ggcaagccug caagauuccc acuuucucac ugacgccgau auggucauga      480

gcuucgugaa ucugguggag caugacaagg aguuuuucca cccccgcuau caucacaggg      540

aauuucgguu cgaucugagu aaaauuccag agggcgaagc cgucaccgca gccgaguucc      600

gcaucuacaa ggacuauauu agggagcggu uugauaacga aacguuccgc aucuccgugu      660

accagguauu gcaggagcac cucgggaggg aaagcgaccu guuucugcuc gauucccgga      720

cucugugggc gagugaggaa gguugguugg uguucgacau caccgccacc agcaaucauu      780

gggucgugaa cccccgccac aaucugggcc uccagcuguc cguggagacu cuggaugggc      840

aaagcauuaa cccaaaauug gcaggccuca ucgguaggca ugggccccag aauaagcagc      900

cguuuauggu cgccuucuuu aaggcaaccg aggugcacuu ccggaguauu agguccacgg      960

gcagcaaaca gcgcagucaa aaccggucca agacucccaa aaaucaggaa gcccugagga     1020

uggccaacgu agcggagaau agcagcuccg accagcgcca agcaugcaag aaacaugaac     1080

uguaugugag uuuucgggac cucggcuggc aggauuggau cauugcccca gagggguacg     1140

ccgcauacua uugugaaggu gagugcgccu ucccccugaa cagcuacaug aaugcgacca     1200

accacgccau cguccagacu uuggugcacu uuauuaaccc agagaccgug cccaagccau     1260

guugcgcacc gacccagcug aaugccaucu ccguccucua uuucgacgau agcaguaacg     1320

ugauccugaa aaaguacagg aauaugguag ugcgcgcaug uggcugccau ugaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  6909
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt7)

<400>  6909
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaggccagcg cagcccugcu cugccuguug cugaccgcgg      120

ccgcauucag uccccagggc cucgcccaac caguggggau caacacuucc accacguguu      180

gcuacagguu uauuaauaaa aagaucccga aacagcggcu ggagagcuau cgcaggacua      240

ccuccaguca cuguccccgg gaagcaguca uuuucaagac caaauuggac aaggagaucu      300

gcgccgaucc aacucagaag ugggugcagg acuuuaugaa acaucuggau aagaaaaccc      360

aaacgcccaa gcucugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  6910
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt7)

<400>  6910
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucaccc ugaucauuuu gcugcccgug gucagcaagu      120

ucuccuuugu gagucucagc gccccacagc acugguccug cccggagggc acucuggcag      180

ggaacgguaa uaguaccugu guaggccccg ccccauucuu gaucuuuagc caugggaacu      240

ccauuuucag gaucgacacg gaaggcacua auuacgagca acuggugguc gacgcgggug      300

ugagcgugau uauggacuuu cacuauaacg aaaaacggau cuacuggguc gaucucgagc      360

gccagcugcu gcagagggug uuccucaaug ggucccggca ggaacgcgua ugcaacaucg      420

agaagaaugu gaguggcaug gccauuaacu ggaucaauga ggaagucauu uggagcaacc      480

aacaggaggg caucauuacc gugaccgaca ugaaagggaa uaacucccau auccuguuga      540

gcgcacugaa guaucccgcc aauguggcag ucgauccagu ggaaagguuu auuuucugga      600

guuccgaggu agccgguagc cucuaccggg cggaccugga uggcgugggg gucaaagccc      660

uguuggagac uuccgaaaag aucaccgcag ugagucucga cgugcuggau aagcgccugu      720

uuuggaucca guauaacagg gagggcagca auucccucau uuguagcugc gacuacgaug      780

gugggagugu ccacaucucc aaacauccca cgcagcacaa ccuguucgcc augagcuugu      840

uuggcgaccg gauuuucuau aguacuugga agaugaaaac caucuggauu gccaacaagc      900

acacuggcaa agauauggug cgcaucaauc ugcauuccag cuucguacca cucggggaac      960

ugaagguggu ccacccgcug gcacaaccca aagccgagga cgacaccugg gaaccagagc     1020

agaaguugug uaagcucagg aaagguaacu gcagcuccac cguguguggc caggaucugc     1080

agagucaucu gugcaugugu gcggaggggu acgcccucag ccgggaccgc aaguacugcg     1140

aagaugucaa ugagugcgca uuuuggaacc acggcuguac gcuggguugc aaaaauacuc     1200

ccggcuccua uuacuguacc ugcccagugg gguucguguu gcugcccgac ggcaagaggu     1260

gucaccaacu cguaagcugc ccgcggaacg ugagugaaug uucccaugau ugcguccuga     1320

cuagcgaggg gccccugugu uuuugcccag aagguuccgu guuggagcgc gacggcaaaa     1380

ccugcagugg guguagcucc cccgauaaug gcgguugcag ccagcucugu gucccacuga     1440

gucccguguc cugggagugc gacuguuucc caggcuauga ucugcagcuc gacgaaaaga     1500

gcugcgccgc auccgggccg caacccuuuc uguuguucgc caacagucag gauaucaggc     1560

acaugcauuu ugacggcacc gacuacggga cucugcucag ccagcagaug ggcauggugu     1620

augcccugga ucacgaccca guagagaaua agauuuacuu cgcgcauacg gcacugaaau     1680

ggaucgaacg ggccaacaug gaugguuccc aacgcgagag guugauugaa gagggggugg     1740

acguccccga gggccuggcc guggauugga ucggucggag guuuuauugg accgaccgcg     1800

gcaagagccu cauugggcgg agugaucuga auggcaaaag guccaagauc aucacuaaag     1860

aaaacauuag ccagccacgc gggaucgcag uccaccccau ggccaagcgg cuguucugga     1920

ccgacaccgg cauuaauccg aggaucgagu ccagcagucu ccaggguuug gggcgccugg     1980

ugauugcgag cuccgaucuc aucuggccaa guggcauuac uaucgacuuu cugacggaua     2040

agcuguacug gugugacgcc aaacagagcg ugaucgaaau ggcaaacuug gauggcucca     2100

agcggaggcg gcugacccaa aaugacguag ggcaccccuu cgccgucgca guguuugagg     2160

acuacgugug guucagcgau ugggccaugc ccuccgucau gcgcgugaac aaaaggacug     2220

guaaggaccg ggugcgccuc cagggcagua ugcugaaacc aagcucccuc guagucgugc     2280

auccccuggc caagccaggg gcagauccgu gcuuguauca gaacggcggu ugugagcaca     2340

uuugcaagaa aaggcugggg accgccuggu guaguugccg ggaaggcuuc augaaggcga     2400

gcgacggcaa aaccugccug gcccucgaug ggcaucagcu guuggccggu ggcgaggugg     2460

accugaagaa ucaagucacu ccccucgaua uccuguccaa aacgcgcgug agcgaagaca     2520

acauuaccga gagucagcac augcucguag cagaaaucau gguguccgau caggacgauu     2580

gugccccagu cgggugcagc auguacgcaa gguguauuuc cgagggcgag gacgcgacuu     2640

gccagugucu gaaggguuuu gccggggacg gcaaauugug cagcgauauc gacgaaugug     2700

agaugggcgu gcccgugugc ccacccgcaa guuccaagug uaucaauacc gaaggggguu     2760

augucugccg gugcagcgag ggcuaccaag gggauggcau ucacugucug gacaucgaug     2820

aaugccagcu gggugagcau aguugugggg agaacgccuc cugcacuaau accgaaggcg     2880

gcuauacgug uaugugcgcc gggaggcuca gcgagccggg ucugauuugu ccagacucca     2940

cucccccacc ccacuugcgc gaagaugacc aucacuacag cgugcggaac agugauagcg     3000

agugcccgcu gucccaugac ggcuauuguc uccacgaugg gguaugcaug uacaucgaag     3060

cacuggacaa guacgccugc aauugugugg ucggcuauau uggugagagg ugccaguacc     3120

gcgaucugaa auggugggag cuccggcacg cgggccaugg gcaacagcag aaggugaucg     3180

uggucgccgu guguguagug guccugguga uguugcugcu ccugaguuug uggggcgcac     3240

acuauuacag gacccagaaa cugcucagca agaaccccaa aaauccauau gaagagucca     3300

gccgcgacgu gcgguccagg cgccccgccg acaccgaaga ugggaugagu agcugcccac     3360

aacccugguu cgucgugauc aaggagcauc aggaccugaa gaacgguggc cagccaguag     3420

ccggggagga uggccaggca gccgacgguu ccaugcaacc gacuagcugg cggcaggaac     3480

cccagcugug uggcaugggg accgagcagg gcugcuggau uccagugagu uccgauaaag     3540

ggagcugucc ccaagucaug gaaagguccu uucacaugcc aaguuacggu acgcagaccc     3600

ucgagggcgg gguggaaaag ccccacagcc uguuguccgc gaauccgcug uggcagcaac     3660

gcgcccucga ucccccacau cagauggagc ugacucagug aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  6911
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt7)

<400>  6911
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggca ggcggaugga gaugcugugc gcagggcgcg      120

ugcccgcccu ccuguugugc cuggguuucc accuccugca ggcggucuug agcacuaccg      180

ugaucccauc cugcauuccg ggcgaaagua gcgacaacug uacggcccug guacaaacug      240

aggauaaucc caggguggca caggucucca ucaccaagug caguagcgac augaacgggu      300

acugucucca uggccagugc auuuaucugg uggauauguc ccagaauuac ugucggugcg      360

aaguggguua uaccgggguc cgcugugagc acuuuuuccu gacugugcau caaccacuca      420

gcaaagaaua cguagcccug accgugaucu ugauuauccu guuucucauc acggucgugg      480

gcuccacuua uuacuucugu aggugguauc ggaaccgcaa gaguaaagag cccaagaaag      540

aguacgaaag ggugaccagc ggcgacccag agcugcccca ggucugagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  6912
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt7)

<400>  6912
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgagggcg aaaucaccac uuucaccgca cugacggaga      120

aguuuaaccu gcccccaggg aauuacaaaa agccgaaacu cuuguauugc agcaacggug      180

gccacuuccu gaggauucuc cccgacggga cuguggaugg cacccgggac cgcuccgauc      240

agcauaucca acugcaguug agugccgaaa gcgucgguga gguguacauu aaguccaccg      300

aaacugggca guaucuggcg auggacaccg auggccuccu guacggcagu cagacgccaa      360

augaggagug ucuguuucuc gaaaggcugg aggaaaacca cuauaauacu uacaucagca      420

aaaagcaugc cgagaagaac ugguucguag gguugaaaaa gaaugguucc ugcaaacggg      480

gcccccgcac ccacuauggg caaaaggcaa uucuguuucu cccacugccc gugagcuccg      540

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  6913
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt7)

<400>  6913
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugggcgucg gggguggcga cguggaggau guaaccccca      120

ggccaggggg cugccagauc agcggucgcg gggcccgggg cuguaacggc auuccggggg      180

cagccgcgug ggaagccgca cugcccaggc ggcgcccaag gcggcacccc uccgugaauc      240

cacgcaguag ggccgcaggu agcccccgga cucgcggcag gcggaccgag gaacgcccau      300

ccgggaguag gcucggcgac cggggucgcg ggagggcccu gccgggcggc cgguugggug      360

ggcgcggcag ggggcgggcg cccgagaggg ucggcggucg cggccggggg aggggcacgg      420

ccgcaccacg cgccgccccc gcagcccggg ggagcaggcc aggucccgcg ggcacuaugg      480

ccgcaggguc caucaccacc cugccggccc uccccgaaga uggcgguagc ggcgcauucc      540

cacccgggca uuuuaaggac ccaaaacgcc uguacugcaa gaacggcggg uucuuuuugc      600

ggauucaccc cgauggcagg guggacggug ugcgggagaa auccgaucca cauaucaagc      660

ugcaacucca ggccgaggaa cgcggggucg ugaguauuaa aggcguaugu gccaauaggu      720

aucuggcgau gaaggaggac ggucggcugc ucgcaagcaa gugcgugacu gaugaauguu      780

ucuuuuucga gcgccuggag uccaacaauu acaacaccua uaggagccgg aaauacacga      840

guugguaugu cgccuugaag cgcacuggcc aguacaaacu gggguccaag accggcccgg      900

ggcagaaagc cauccucuuu cugcccauga gcgcaaaguc cugaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  6914
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt7)

<400>  6914
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaagugga uccugaccug gauucucccc acucuguugu      120

acaggagcug cuuccauauc auuugucugg ugggcaccau cucccucgcc ugcaacgaca      180

ugacgccaga gcagauggca acuaauguca acuguaguag cccggaacgg cacacccgcu      240

ccuaugauua cauggaaggg ggugacauua gggugcggcg ccuguuuugc aggacccaau      300

gguauuugcg gaucgauaaa cgcggcaagg uaaaagggac ucaggagaug aagaauaacu      360

acaauaucau ggagauuagg accguggccg ucggcaucgu ggcgauuaaa gguguggaaa      420

gugaguucua ucuggccaug aacaaggagg ggaagcucua cgccaaaaag gaauguaaug      480

aggacugcaa cuuuaaagaa cugauccugg agaaucauua uaacacguac gcaagcgcaa      540

aguggacuca caauggcggc gagauguucg ucgcccucaa ccagaaaggg auucccgugc      600

gggguaagaa aaccaagaag gaacagaaaa cugcgcauuu ucugccaaug gccaucaccu      660

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  6915
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt7)

<400>  6915
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugcucc ccagcguggu ccugaaauug uuccuggccg      120

cagugcucuc cgcccuggua accggcgaga guuuggaaag gcugcggcgc gggcucgcgg      180

ccgguacuag caacccagac ccgcccaccg uguccacgga ucagcugcug ccacucggcg      240

ggggcaggga ccggaagguc cgcgaucugc aagaggcaga cuuggaucug cucaggguga      300

cucugaguag caaaccccag gcccuggcaa ccccaaauaa ggaggaacac gguaaacgga      360

agaagaaagg gaagggcuug ggcaaaaagc gcgaccccug ccucaggaaa uacaaggauu      420

uuuguaucca uggggaaugc aaauauguga aggagcugcg ggccccaucc uguauuugcc      480

acccggguua ccauggcgag cgcugucacg ggcugagccu ccccgucgaa aacaggcugu      540

auaccuacga ccauacuacc aucuuggcgg ugguagccgu gguccugucc agugugugcc      600

uccuggugau ugucggccug uugauguucc gguaucaccg cagggguggg uacgaugugg      660

agaaugaaga gaagguaaaa cucggcauga cgaacagcca cugaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  6916
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt7)

<400>  6916
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggugacca agcugcuccc cgcccuguug cugcagcacg      120

uccuccugca uuugcugcuc cugccaaucg caauuccgua cgccgagggc caaaggaaac      180

ggcgcaacac uauccacgaa uuuaagaaaa gcgcgaagac cacgcugauu aaaaucgacc      240

ccgcccucaa gauuaagacu aaaaagguga auaccgcaga ucagugcgcc aacaggugua      300

cccggaauaa agggcugcca uucacuugca aggcauucgu auuugacaaa gcccgcaagc      360

aguguuugug guuccccuuu aacuccauga guagcggugu gaaaaaggag uucggccaug      420

aauuugaucu guaugagaau aaggacuaca ucaggaacug caucauuggg aaaggccggu      480

ccuauaaggg uaccgucagu aucacgaaaa gcgggauuaa gugucagcca ugguccagca      540

ugauccccca cgaacauucc uuccucccaa guagcuaccg cggcaaagau cugcaagaga      600

auuauugcag gaacccgcgg ggcgaggaag ggggucccug guguuuuacu uccaauccag      660

aggugcgcua cgaagugugc gacauucccc aguguagcga ggucgagugc augaccugca      720

acggcgaaag uuauaggggg cugauggauc acacugaguc cggcaagauc ugucagcggu      780

gggaccacca gaccccacau cgccacaagu ucuugcccga aagguacccg gauaaagguu      840

uugacgauaa uuacugccgg aaccccgacg ggcaaccacg ccccuggugu uauacccucg      900

auccacauac gaggugggag uacugcgcga uuaagacuug ugccgacaau accaugaacg      960

acacugaugu gccccuggaa accaccgagu gcauccaggg ccagggcgag ggguaucggg     1020

guacuguaaa uacgaucugg aacggcauuc caugucagcg cugggacagc caauacccgc     1080

acgaacacga uaugaccccc gagaacuuca aaugcaagga ccugagggaa aauuauuguc     1140

ggaacccaga uggguccgag agucccuggu gcuucacuac cgacccaaau aucagggugg     1200

gcuacugcag ccagauuccc aacugugaua ugucccaugg ucaggacugc uaucgcggca     1260

augggaaaaa cuacaugggc aaucucagcc aaacccggag ugggcugacu uguuccaugu     1320

gggauaagaa cauggaagac uugcacaggc auaucuuuug ggagccggau gcaagcaagc     1380

ugaaugagaa cuacugccgc aauccagacg acgaugccca cggucccugg uguuauacgg     1440

gcaacccccu cauuccaugg gacuacugcc ccaucagucg gugugaaggg gauaccacuc     1500

caaccaucgu caaucuggac cauccgguga uuuccugcgc caaaaccaag cagcugaggg     1560

uggucaacgg cauccccacu cgcacgaaua uugguuggau ggugagcuug cgguauagga     1620

acaaacacau cuguggcggg agccucauua aggaguccug gguacugacc gcacggcagu     1680

gcuucccaag ucgcgaucug aaagacuacg aagccuggcu cggcauccac gaugugcaug     1740

ggaggggcga cgagaagugu aagcaggucc ugaacgugag ccaauuggug uauggucccg     1800

aaggguccga ucugguccuc augaaacugg cgcggccagc cgugcuggac gauuuuguaa     1860

gcacuaucga cuugcccaau uacggcugca ccauuccgga gaagaccagu ugcuccgugu     1920

augguugggg cuacacuggg cucaucaacu acgauggccu gcugcgcguc gcacaccucu     1980

auauuauggg gaaugagaaa uguagccagc aucacagggg caaggugacg cugaacgaau     2040

ccgagaucug cgccggugca gagaaaauug ggaguggccc augugaaggc gacuacgggg     2100

gucccuuggu cugcgagcag cacaagaugc ggauggugcu gggcgugauc guaccagggc     2160

gcggcugugc cauucccaau aggccgggua ucuucgugcg ggucgccuau uacgcgaaau     2220

ggauccauaa gauuauccuc accuauaagg ugccccagag cugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  6917
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt7)

<400>  6917
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggcag ccgcgaucgg cauugaccug gggaccacuu      120

acagcugcgu gggugucuuc cagcacggca aaguggagau cauugccaac gaucaaggga      180

auaggaccac gcccuccuau guagcauuua cugacaccga acggcucauc ggcgaugccg      240

caaagaacca gguggcccug aauccacaga acaccgucuu cgacgcgaaa cgcuugauug      300

guaggaaguu uggggauccg guggugcaga gugacaugaa acauuggccc uuccaaguca      360

ucaaugaugg cgacaagcca aaggugcagg uaagcuacaa aggcgagacu aaggccuuuu      420

aucccgaaga gaucuccagu auggugcuga ccaaaaugaa ggaaauugca gaggccuacc      480

ucggguaucc agucacgaac gccgugauca cugugcccgc auacuucaau gauagccagc      540

ggcaggccac caaagacgcg ggugucauug ccggccugaa cguguugcgc aucauuaaug      600

agccaacugc agccgcaauc gccuaugggc uggauaggac cggcaagggu gaacggaacg      660

uacucauuuu ugaccucggg ggcggcaccu ucgauguguc cauccugacg aucgacgacg      720

ggauuuuuga ggucaaagcc acugcgggug auacccaccu gggcggggaa gacuucgaua      780

aucgccuggu gaaccauuuu guggaggagu ucaagaggaa gcacaaaaag gacaucagcc      840

aaaauaaacg ggcaguccgc agguugcgga cugccuguga acgcgccaag aggacccugu      900

ccaguagcac ccaggcaucc cucgagauug auagccuguu cgaaggcauc gacuuuuaca      960

cuagcauuac gcgggcccgc uucgaggaac ugugcuccga uuuguuuagg agcacccucg     1020

agccggugga gaaagcgcug cgggacgcca agcuggauaa ggcacagauc caugaccucg     1080

uacugguggg uggcuccacu cgcaucccca aaguccagaa guugcugcaa gauuucuuua     1140

acgggaggga ccucaauaaa aguauuaacc cagacgaagc cguggcauac ggcgccgccg     1200

uccaggcagc cauccugaug ggggauaaga gcgagaacgu gcaggaccug uugcuccugg     1260

auguggcgcc ccugucccuc ggucuggaaa ccgccggcgg gguaaugacc gcauugauua     1320

aacggaauag cacuauccca acgaagcaaa cccagauuuu cacuaccuau agugacaacc     1380

agcccggcgu gcugauccag gucuacgagg gugaaagggc caugaccaag gauaauaacc     1440

uccugggccg cuuugagcug uccgggaucc cgcccgcccc acggggcgug ccccaaauug     1500

aggucacuuu cgacaucgau gcaaauggga uuuugaacgu gacggcgacc gacaaaagca     1560

cuggcaaggc caauaaaauc accauuacua acgauaaggg uaggcucagu aaagaagaga     1620

ucgaacgcau ggugcaggag gcagaaaagu auaaggccga ggacgaggua cagcgggaaa     1680

ggguguccgc caaaaaugca cuggagagcu acgccuuuaa caugaagagu gcggucgaag     1740

augaggggcu gaaaggcaag auuuccgagg ccgacaaaaa gaaagugcuc gauaaguguc     1800

aggaagucau caguuggcug gacgcaaaua ccuuggccga gaaggacgag uucgaacaca     1860

aacgcaagga acuggagcaa gugugcaacc caaucauuag cggucucuau cagggcgccg     1920

ggggccccgg gccaggcggu uuuggggcac agggcccgaa aggcgggucc gguagcggcc     1980

ccacgaucga ggaaguggau ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6918
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt7)

<400>  6918
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaggcag ccgcgaucgg cauugaccug gggaccacuu      120

acagcugcgu gggugucuuc cagcacggca aaguggagau cauugccaac gaucaaggga      180

auaggaccac gcccuccuau guagcauuua cugacaccga acggcucauc ggcgaugccg      240

caaagaacca gguggcccug aauccacaga acaccgucuu cgacgcgaaa cgcuugauug      300

guaggaaguu uggggauccg guggugcaga gugacaugaa acauuggccc uuccaaguca      360

ucaaugaugg cgacaagcca aaggugcagg uaagcuacaa aggcgagacu aaggccuuuu      420

aucccgaaga gaucuccagu auggugcuga ccaaaaugaa ggaaauugca gaggccuacc      480

ucggguaucc agucacgaac gccgugauca cugugcccgc auacuucaau gauagccagc      540

ggcaggccac caaagacgcg ggugucauug ccggccugaa cguguugcgc aucauuaaug      600

agccaacugc agccgcaauc gccuaugggc uggauaggac cggcaagggu gaacggaacg      660

uacucauuuu ugaccucggg ggcggcaccu ucgauguguc cauccugacg aucgacgacg      720

ggauuuuuga ggucaaagcc acugcgggug auacccaccu gggcggggaa gacuucgaua      780

aucgccuggu gaaccauuuu guggaggagu ucaagaggaa gcacaaaaag gacaucagcc      840

aaaauaaacg ggcaguccgc agguugcgga cugccuguga acgcgccaag aggacccugu      900

ccaguagcac ccaggcaucc cucgagauug auagccuguu cgaaggcauc gacuuuuaca      960

cuagcauuac gcgggcccgc uucgaggaac ugugcuccga uuuguuuagg agcacccucg     1020

agccggugga gaaagcgcug cgggacgcca agcuggauaa ggcacagauc caugaccucg     1080

uacugguggg uggcuccacu cgcaucccca aaguccagaa guugcugcaa gauuucuuua     1140

acgggaggga ccucaauaaa aguauuaacc cagacgaagc cguggcauac ggcgccgccg     1200

uccaggcagc cauccugaug ggggauaaga gcgagaacgu gcaggaccug uugcuccugg     1260

auguggcgcc ccugucccuc ggucuggaaa ccgccggcgg gguaaugacc gcauugauua     1320

aacggaauag cacuauccca acgaagcaaa cccagauuuu cacuaccuau agugacaacc     1380

agcccggcgu gcugauccag gucuacgagg gugaaagggc caugaccaag gauaauaacc     1440

uccugggccg cuuugagcug uccgggaucc cgcccgcccc acggggcgug ccccaaauug     1500

aggucacuuu cgacaucgau gcaaauggga uuuugaacgu gacggcgacc gacaaaagca     1560

cuggcaaggc caauaaaauc accauuacua acgauaaggg uaggcucagu aaagaagaga     1620

ucgaacgcau ggugcaggag gcagaaaagu auaaggccga ggacgaggua cagcgggaaa     1680

ggguguccgc caaaaaugca cuggagagcu acgccuuuaa caugaagagu gcggucgaag     1740

augaggggcu gaaaggcaag auuuccgagg ccgacaaaaa gaaagugcuc gauaaguguc     1800

aggaagucau caguuggcug gacgcaaaua ccuuggccga gaaggacgag uucgaacaca     1860

aacgcaagga acuggagcaa gugugcaacc caaucauuag cggucucuau cagggcgccg     1920

ggggccccgg gccaggcggu uuuggggcac agggcccgaa aggcgggucc gguagcggcc     1980

ccacgaucga ggaaguggau ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6919
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt7)

<400>  6919
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaccgcaa agggcaucgc cauugggauc gaccugggua      120

cuaccuacag cugcgugggc gucuuccagc acgggaaagu ggagauuauc gcgaacgauc      180

aaggcaauag gacgacuccc uccuauguag ccuuuaccga caccgaacgg cucauuggug      240

augcagccaa gaaccaggug gcaaugaauc cacagaacac ugucuucgac gccaaacgcc      300

ugaucgggag gaaguuuaau gauccggugg ugcaggcgga caugaaauug uggcccuucc      360

aagucaucaa cgagggcggc aagccaaagg ugcugguaag uuacaaaggg gaaaauaagg      420

ccuuuuaucc cgaggaaauu agcuccaugg ugcucaccaa acugaaggag acggcagagg      480

ccuucuuggg ucauccaguc acuaacgccg ugaucaccgu gcccgcauac uuuaaugaua      540

gucagcggca ggccacuaaa gacgcgggcg ucauugccgg gcugaacgug cuccgcauca      600

uuaaugaacc aaccgcagcc gcaaucgccu auggccugga uaaggguggg cagggcgaga      660

ggcacguacu gauuuucgac cucggcgggg guaccuuuga ugugagcauc cugacgaucg      720

acgauggcau uuucgaaguc aaagccacug cgggggacac ccauuugggc ggugaggacu      780

uugauaaccg gcuggugucc cacuucgugg aggaguucaa gcgcaagcau aaaaaggaca      840

ucagccaaaa uaaaagggca guccggcgcc ucaggacugc cugugagcgg gccaagcgca      900

cccuguccag uagcacccag gcaaaccugg aaauugauuc cuuguacgag ggcaucgacu      960

uuuauacuag cauuacgagg gcccgguucg aagaacucug cgcggaucug uuucgcggga     1020

cccuggagcc gguggaaaaa gcccucaggg acgcaaagau ggauaaggcc aaaauccacg     1080

acaucguacu ggugggcggg aguacucgga uucccaaggu ccagcgcuug cugcaggauu     1140

acuucaaugg uagggaccuc aacaaaucca ucaacccaga ugaggcagug gccuacggcg     1200

ccgcagucca agccgcgauu cugauggggg acaagagcga aaaagugcag gaccuguugc     1260

uccuggaugu ggcaccccug ucccucggcc uggagaccgc cgguggcgua augaccgccu     1320

ugaucaagcg gaauaguacu auuccaacga agcagaccca aaucuuuacu accuauagcg     1380

acaaccagcc cggggugcug auccaggucu acgaaggcga gagggccaug accaaagaua     1440

auaaccuccu ggggcgcuuc gaccugacug gcauuccgcc cgcaccacgg ggugugcccc     1500

agaucgaggu cacguuugau auugacgcga augggaucuu gaacgugacc gccacugaua     1560

aguccaccgg caaagugaau aagauuacua ucaccaacga caaagguagg cucagcaagg     1620

aagagauuga acgcauggua cuggaugcag agaaguauaa agccgaagac gaggugcaac     1680

gggagaagau cgccgccaaa aaugcacugg aaaguuacgc guucaacaug aaguccgucg     1740

ugagcgauga gggccucaaa gggaagauca gugaauccga caaaaauaag auucuggaua     1800

aguguaacga guugcugagc uggcucgagg ucaaucagcu ggccgaaaaa gacgaguuug     1860

accacaagag gaaagaacug gagcagaugu gcaacccaau cauuacgaag uuguaucagg     1920

gcggguguac cggccccgca ugcgguacug gguacgugcc aggccgcccg gccaccggcc     1980

ccacuaucga agagguggau ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  6920
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt7)

<400>  6920
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgccaggg gccccgcaau cgggauugac cuggguacca      120

cuuacuccug cgugggcguc uuccagcacg ggaaggugga gaucauugcc aacgaucagg      180

gcaaucggac cacgccaagu uauguagcgu uuacugacac cgaacgccuc aucggugaug      240

ccgccaaaaa ccagguggca augaauccga ccaacacuau uuucgacgca aagaggcuga      300

ucgggcggaa auuugaggau gccaccgucc agagcgacau gaagcauugg cccuuccgcg      360

ugguguccga aggcggcaaa ccaaaggucc agguggagua caagggggaa acgaaaaccu      420

uuuuccccga ggagaucagu agcaugguau ugacuaagau gaaagaaauu gcggaggccu      480

aucugggugg caaggugcac uccgcaguca ucacugugcc agccuacuuu aaugauagcc      540

aaaggcaggc caccaaagac gcagggacca uuacgggccu caacgugcug cggaucauua      600

augaacccac ugccgcggcc aucgcauaug guuuggauaa gaaagggugu gccggcggcg      660

agaagaacgu ccugauuuuc gaccucgggg guggcaccuu ugaugugucc auccugacua      720

ucgaggacgg gauuuucgaa guaaagagua ccgcaggcga uacccaucug gguggcgagg      780

acuuugacaa ucgcauggug agccaccucg ccgaagaguu caaaaggaag cauaaaaagg      840

auaucgggcc aaacaaacgg gccguccgca ggcugcggac ugcgugcgaa cgcgcaaaga      900

ggacguuguc cagcaguacc caggccucca uugagaucga cagccuguac gagggcgugg      960

auuucuauac uuccauuacc cgggcccgcu uugaggaacu caaugcagac cuguucaggg     1020

ggacccugga accgguggag aaggccuugc gggaugcgaa acucgacaag ggucagaucc     1080

aagaaaucgu ccuggugggc gggaguacuc gcauucccaa aauccagaag cugcuccagg     1140

acuuuuucaa cggcaaagag cugaauaaga gcauuaaccc agaugaggcc guagcauacg     1200

gugccgcagu gcaggccgcc aucuugauug gcgauaaguc cgaaaauguc caagaccugc     1260

uccugcugga ugugacgccc uugagccucg ggaucgagac cgcaggcggg gucaugacuc     1320

cacugaucaa aaggaacacc accauuccca cuaagcagac gcagaccuuu acuaccuaca     1380

gugacaacca auccagcgug cuggugcagg uauaugaagg cgagcgggcc augacuaaag     1440

acaauaaccu ccuggguaag uucgauuuga ccgggauccc gcccgcgcca aggggcgugc     1500

cccagauuga agucacguuu gacaucgaug ccaaugguau ucugaacgug accgcagccg     1560

acaaaaguac uggcaaggag aauaagauca ccauuacuaa cgauaaaggg cgccucucca     1620

aggacgauau cgaccggaug guccaggagg ccgaaaggua caaaagcgag gaugaagcaa     1680

aucgcgaccg gguggcggcc aagaacgcac uggagagcua uaccuacaau aucaaacaaa     1740

cgguggagga ugaaaagcug aggggcaaaa uuuccgagca ggacaagaac aagaucuugg     1800

auaaauguca ggaaguaauu aauuggcucg accgcaacca gauggccgag aaggacgaau     1860

augagcacaa acaaaaggag cuggaacggg ugugcaaucc aaucauuagu aaacuguacc     1920

aagggggccc cggugggggc agcggcgggg guggcuccgg ggccagcggc gguccaacca     1980

ucgaggaagu cgauugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  6921
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt7)

<400>  6921
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccag uccugcuacg      120

uggccguagc aagggccggu ggcauugaga ccaucgcgaa cgaauauagu gaucggugua      180

cucccgccug cauuagcuuu gggccaaaga aucgcuccau cggcgcagcc gcaaaaaguc      240

aagugauuag caacgccaag aauaccgucc aggguuucaa aagguuucac gggcgggcgu      300

ucuccgaccc guuuguggag gccgaaaaga gcaaccucgc auacgauauc gugcagcugc      360

ccacgggcuu gacuggcauc aaagucaccu auauggagga agaacgcaau uucaccacug      420

aacaggugac cgccaugcug cucuccaagc ugaaggaaac ggccgagagu guauugaaaa      480

agccaguggu cgacugugug gugagcgucc ccugcuuuua cacugaugca gaaaggcggu      540

ccgugaugga cgccacccaa auugcggggc ugaacugucu ccgccugaug aaugagacua      600

ccgccguagc acuggccuau gguaucuaca aacaggaucu cccagcacug gaggaaaagc      660

ccaggaacgu ggucuucgug gacaugggcc auagcgccua ucaggugagu gucugcgccu      720

uuaaucgggg gaaauugaag gugcuggcga ccgcauucga uacgacucuc ggcggucgca      780

aauuugacga gguacuggug aaccacuucu gugaagaguu cgggaagaag uacaaacugg      840

auauuaaguc caaaaucagg gccuugcucc ggcugagcca ggaaugcgag aagcugaaaa      900

agcucauguc cgccaaugca agugaccugc cauugagcau ugaguguuuu augaacgaug      960

ucgacguguc cggcaccaug aaucgcggca aguuccugga aaugugcaac gaccuccugg     1020

ccagggucga gccgccccug cggagcgugu uggaacaaac uaaacucaag aaagaggaua     1080

ucuacgcggu ggaaauugua gggggugcca cccgcauccc agcagugaag gagaaaauca     1140

guaaguuuuu cggcaaggag cuguccacca cucugaaugc cgacgaagca gucacgaggg     1200

ggugcgcccu ccagugugcc auucugagcc ccgcauuuaa agugcgggag uucaguauca     1260

ccgaugucgu gccauauccc auuuccuugc gcuggaacag cccggccgaa gagggcagcu     1320

ccgacugcga aguguuuagu aagaaccaug cggcccccuu cagcaaagua cugacuuuuu     1380

acaggaagga gccauucacc cucgaggcau auuacuccag cccccaggau cugccauauc     1440

ccgacccagc caucgcccag uuuagugugc aaaaagucac cccgcagucc gaugguagcu     1500

ccaguaaggu gaaggucaaa gugcggguga auguacacgg cauuuucagc gucuccagcg     1560

caagucuggu ggaagugcau aaguccgagg aaaacgagga gcccauggaa acugaccaga     1620

augcgaaaga ggaagagaag augcaagucg aucaggagga gccacacgug gaggaacagc     1680

agcaacagac gcccgccgag aacaaagcag aaagcgagga aauggagacc ucccaggccg     1740

ggaguaagga caaaaagaug gaucagccac cccaagccaa gaaagcaaag gugaaaacua     1800

gcaccguaga cuugccgauc gagaaucagc uccuguggca gaucgacagg gaaaugcuga     1860

accucuacau ugagaaugaa ggcaagauga ucaugcagga uaaacuggag aaggaacgca     1920

acgacgccaa gaaugcgguc gaggaguaug uguacgaaau gcgggauaaa uuguccgggg     1980

aguacgaaaa guuugugagc gaggacgaua ggaacaguuu cacccugaaa cucgaggaca     2040

cugaaaauug gcuguaugag gauggugaag accaaccaaa gcaggucuac guggauaaac     2100

uggccgaguu gaagaaccug ggccagccca uuaagauccg cuuccaggaa uccgaggagc     2160

ggcccaaacu cuuugaggag cuggggaagc aaauucagca guauaugaaa aucaucagcu     2220

ccuucaagaa uaaagaagac caauacgauc accucgacgc agccgauaug acgaagguag     2280

agaaaagcac caacgaagcc auggagugga ugaauaacaa gcugaacuug cagaauaagc     2340

agagucugac uauggaccca guggucaaaa gcaaggagau ugaagcaaaa aucaaggagc     2400

ucaccuccac uuguaguccc auuaucagca aaccaaagcc gaagguggaa cccccaaaag     2460

aggagcagaa gaacgccgaa caaaauggcc ccguggacgg ucagggcgau aacccagggc     2520

cccaggcggc cgagcagggc accgacacgg cagucccguc cgauagcgac aaaaagcugc     2580

cagaaaugga uauugacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  6922
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt7)

<400>  6922
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gcaucgaccu gggguuccuc aacugcuaca      120

uugccguggc aagguccggu ggcaucgaga ccauugccaa ugaauauagu gaucggugua      180

cucccgcgug caucagccug gggucccgca ccagggccau uggcaacgca gccaagaguc      240

agaucguaac gaaugugcgg aacacuaucc acgguuuuaa aaaguugcau gggcgcagcu      300

ucgacgaucc aauuguccaa accgagagga uccggcugcc guacgaacuc cagaaaaugc      360

ccaauggcuc cgcaggcgug aaggugcgcu aucuggagga agagaggcca uuugccauug      420

agcaggucac cgggauguug cuggcgaaac ucaaggaaac uagcgagaac gcccugaaga      480

aacccguggc agacugugua aucuccauuc caaguuucuu uaccgaugcc gaacggcgca      540

gcgugauggc cgcagcccag gucgcggguc ugaauugccu caggcugaug aacgagacga      600

cugccguggc auuggccuac ggcaucuaua agcaagaccu gcccccacuc gaugagaaac      660

cgcggaaugu ggucuucauu gacauggggc acuccgcaua ccaggugcug guaugugccu      720

uuaacaaggg caaacugaag guguuggcca ccacuuucga ucccuaucuc ggugggcgca      780

auuuugacga agcgcugguc gauuacuucu gcgacgaguu uaaaaccaag uacaagauca      840

acgugaaaga aaauagcagg gcacugcucc ggcuguauca ggagugugaa aaguugaaaa      900

agcugaugag ugccaacgcc uccgaucucc cacugaauau cgagugcuuc augaacgacc      960

uggacgugag cuccaaaaug aaccgcgcac aguucgagca auugugugcc agucuccugg     1020

cgagggucga acccccacug aaggccguga uggagcaggc aaaucuccag cgggaagaua     1080

uuagcuccau cgagauugua ggcggcgcca cccgcauccc cgcagugaag gaacagauua     1140

cgaaauuuuu ccugaaggac aucagcacua ccuugaacgc cgaugaggcc gucgcaaggg     1200

ggugcgcccu gcaaugcgcg auccucaguc cggccuuuaa agugcgggag uucuccauua     1260

cugaccuggu ccccuacagc aucacccuga gguggaagac caguuuugaa gaugguuccg     1320

gcgaguguga aguguucugc aaaaaucauc cagcacccuu uagcaaggug auuacuuucc     1380

acaagaaaga gccauuugaa uuggaggccu ucuauacgaa ccuccaugag guacccuacc     1440

cagacgcccg caucgggagc uuuaccauuc agaauguguu cccgcagucc gauggcgaca     1500

guagcaaggu caaagugaag guccggguga acauccacgg uaucuuuucc guggcaagcg     1560

cgaguguaau ugaaaaacaa aaucuggagg gcgaucacuc cgacgccccc auggaaacug     1620

agaccagcuu caagaacgag aauaaggaua acauggacaa aaugcaagug gaccaggaag     1680

aggggcauca gaagugucac gcagaacaua ccccagagga agagaucgau cacacuggcg     1740

ccaaaacgaa guccgccguc agugacaaac aggauaggcu gaaucagacc cucaagaaag     1800

ggaaggugaa guccauugac cugcccaucc aguccagcuu gugccgccag cugggucaag     1860

aucuccugaa caguuauauu gagaaugaag gcaaaaugau caugcaggac aagcuggaga     1920

aagaacggaa cgaugcaaag aaugccgucg aggaauacgu guaugacuuc agggaucgcu     1980

uggggacugu guacgagaaa uuuauuaccc cagaggaccu guccaagcuc agcgcgguac     2040

uggaagauac cgagaacugg cucuacgaag acggcgagga ucagcccaag caggucuaug     2100

uggacaaacu gcaagaauug aagaaauacg gucagccgau ccagaugaag uauauggagc     2160

acgaggaacg gccaaaagcc cugaacgacc ucggcaagaa gauccagcug gugaugaaag     2220

ucauugaggc auacaggaau aaggaugaac gguaugacca ucuggauccc acugagaugg     2280

agaaagugga aaaguguauc uccgacgcca ugaguugguu gaacagcaaa augaaugccc     2340

aaaacaagcu gucccucacg caggaucccg ugguaaaagu cagcgagauu guggcaaaga     2400

guaaggaacu ggacaauuuc ugcaacccaa ucauuuacaa acccaagcca aaagccgagg     2460

ugccggaaga uaagcccaaa gcgaauagcg agcacaacgg gccaauggac ggccagagcg     2520

ggaccgagac uaaguccgau agcaccaagg acaguagcca acauacuaaa uccaguggcg     2580

aaauggaggu cgauugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  6923
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt7)

<400>  6923
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcugagcc ucguggccgc aaugcuguug cugcucuccg      120

ccgcgagggc cgaggaagag gacaaaaagg aagaugucgg caccguggua gggaucgacc      180

uggguacuac cuacaguugc gugggcgucu ucaaaaacgg gcggguggag auuaucgcaa      240

augaucaggg caaccgcauu acgcccagcu auguggccuu uacuccagaa ggugagaggu      300

ugaucgggga cgcagccaag aaucaacuga ccuccaaccc ggagaauacc gucuucgaug      360

cgaaacggcu cauuggccgc acuuggaacg accccagugu gcagcaggau aucaaguuuc      420

ugccauucaa gguaguggag aaaaagacca aacccuacau ccaggucgac auuggcgggg      480

gucaaacgaa gacuuuugcc ccagaagaaa ucagcgcaau ggugcugacc aaaaugaagg      540

agacugccga ggccuaucuc ggcaaaaagg ugacccacgc agucgugacc guacccgccu      600

acuucaauga ugcgcagagg caggccacga aggacgcagg gacuauugcc ggccugaacg      660

ugaugcggau cauuaaugaa ccaaccgcag ccgccaucgc guaugguuug gauaaacgcg      720

agggggaaaa gaacauucug gucuuugacc ucggcggcgg gacuuucgau gugucccugc      780

ugaccaucga caauggugug uuugaggucg uggcaaccaa cggcgacacu caucucgggg      840

gcgaagauuu cgaccagagg guaauggagc acuuuaucaa auuguacaag aaaaagacgg      900

guaaggaugu gcggaaagac aaucgcgccg uccaaaagcu gaggcgggag guggaaaaag      960

ccaagcgcgc acugagcucc cagcaucagg ccaggauuga gaucgaaagu uucuaugagg     1020

gcgaagauuu cagcgagacc cucacucggg cgaaauuuga ggaacugaac auggacuugu     1080

uccgcuccac caugaagccg guccagaagg ugcuggagga uagcgaccuc aaaaagagug     1140

auauugacga aaucgugcug guagggggcu ccaccaggau ucccaaaauc caacagcugg     1200

ugaaggaguu uuucaauggg aaagaaccaa gccgggguau caaccccgau gaggccgucg     1260

cauacggcgc cgcagugcag gccggggucu uguccggcga ccaagacacu ggugaucucg     1320

ugcugcugga cgugugucca cucacgcugg gcauugagac cguagggggc gugaugacua     1380

aguugauccc ccgcaacacc gucgugccga ccaagaaaag ucagauuuuu agcacugccu     1440

ccgauaauca gcccacgguc accaucaagg uguacgaagg ggagaggcca cugacuaaag     1500

acaaccaccu ccugggcacc uucgaucuga cugguauucc cccagcaccc cggggcgugc     1560

cacagaucga aguaaccuuu gagaucgacg ucaaugggau uuugagggug acggccgagg     1620

auaaggguac cggcaacaaa aauaagauca cuauuaccaa cgaccaaaau cgccucacuc     1680

cggaagagau cgaacggaug gugaacgaug cggagaaauu cgccgaagag gacaagaagc     1740

ugaaagagag gauugauacc cgcaaugaac uggagagcua ugcauacagu cucaagaacc     1800

agaucgggga caaagaaaag cugggcggga aauuguccag cgaggauaag gaaacgaugg     1860

agaaggccgu cgaggagaaa auugaauggc uggaaaguca ucaggacgcc gacaucgagg     1920

auuuuaaggc gaaaaagaaa gaacucgagg agaucgugca gcccauuauc uccaagcugu     1980

auggcagcgc agguccaccc ccaaccgggg aagaggacac ugccgaaaag gaugagcugu     2040

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  6924
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt7)

<400>  6924
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gggagcuggc agugggcauc gaccucggga      120

ccacuuacag cugcgucggu guguuccaac agggccgggu agaaauucug gccaacgauc      180

aggggaaucg caccacgcca uccuaugugg cguuuacuga caccgagagg uuggucggcg      240

augccgcaaa gagucaggcc gcacugaacc cgcacaauac cguguucgac gccaaacggc      300

ucaucggucg caaguuugcg gauacuaccg ugcaaagcga caugaaacau uggcccuuca      360

gggucguguc cgaagggggc aagccaaaag uacgggugug uuaccgcggc gaggauaaga      420

cguuuuaucc cgaagagauu aguagcaugg uccuguccaa gaugaaagag acugccgaag      480

cauacuuggg gcagccagug aagcacgccg ugaucaccgu ccccgccuau uucaacgaca      540

gccagaggca ggcaacuaaa gaugccggug cgauugccgg ccugaaugug cuccggauca      600

ucaacgagcc aaccgcagcc gcaauugccu acgggcugga ccgcaggggc gccggugaac      660

ggaauguacu gaucuuugau cucgggggcg gcaccuucga cguguccguc cugaguauug      720

augcgggggu guuugaggug aaggcaacgg ccggugacac ucauuugggc ggggaggacu      780

ucgauaaccg ccuggucaau cacuuuaugg aagaguucag gcggaaacau ggcaaggacc      840

ucagcgguaa caaacgcgcc cugaggcggc ugcgcaccgc augcgaaagg gccaagcgga      900

cuuuguccag caguacccaa gcgacccucg agaucgauuc ccuguucgaa ggcguggacu      960

uuuauacuag cauuacgagg gcccgcuucg aggagcugug uuccgaucuc uuucggagua     1020

cccuggaacc gguagagaag gcauugaggg acgccaaacu ggauaaggca cagauccacg     1080

acgugguccu cgucgggggc agcacucgca uucccaaagu gcagaagcug cugcaggauu     1140

ucuuuaaugg gaaagaauug aacaagucca ucaauccaga cgaggccgug gccuacggug     1200

cagccgugca agcggccgua cucaugggcg auaagugcga aaaagugcag gaccugcugc     1260

uccuggacgu cgcacccuug agccuggggc ucgagaccgc cggcggugug augaccacuc     1320

ugauccagcg gaacgccacg auuccaacca agcaaacuca gaccuucacc acuuacagug     1380

auaaucagcc cggcgucuuu auccaggugu augaggggga aagggcaaug acgaaagaca     1440

acaaccuguu gggccgcuuc gagcucuccg ggauuccgcc cgcgccacgg ggcgugcccc     1500

aaaucgaagu aaccuuugau auugacgcca augguauccu gagcgugacu gcaaccgaua     1560

ggaguacugg gaaggccaac aaaaucacca uuacgaauga caagggccgg cuguccaagg     1620

aggaagucga gcgcauggug cacgaggccg aacaguacaa agcagaggau gaagcccaga     1680

gggaccgggu cgcggccaag aacagccucg aggcacaugu guuccacgug aaagguagcc     1740

ugcaggagga auccuugcgc gauaagaucc cagaggaaga caggcggaaa augcaagaua     1800

agugucgcga gguacuggcc uggcucgaac auaaucagcu ggccgagaag gaggaauaug     1860

agcaccagaa aagggaacug gagcagauuu gccggcccau cuuuaguagg uuguacggcg     1920

ggccaggcgu ccccgggggc agcuccugug guacccaagc acgccagggg gacccgagca     1980

cuggcccaau uaucgaagag guggauugag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  6925
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt7)

<400>  6925
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caggccccca gggagcuggc agugggcauc gaccucggga      120

ccacuuacag cugcgucggu guguuccaac agggccgggu agaaauucug gccaacgauc      180

aggggaaucg caccacgcca uccuaugugg cguuuacuga caccgagagg uuggucggcg      240

augccgcaaa gagucaggcc gcacugaacc cgcacaauac cguguucgac gccaaacggc      300

ucaucggucg caaguuugcg gauacuaccg ugcaaagcga caugaaacau uggcccuucc      360

aggucguguc cgaagggggc aagccaaaag uaagggugug uuaccggggc gaggauaaga      420

cguuuuaucc cgaagagauu aguagcaugg uccuguccaa gaugaaagag acugccgaag      480

cauacuuggg gcagccagug aagcacgccg ugaucaccgu ccccacuuau uucagcaacu      540

cccagcgcca agccaccaaa gacgcagggg ccauugcggg ccugaaggug cucccaauca      600

ucaaugaggc caccgcagcc gcaauugccu acgggcugga uaggcggggc gccgguaaac      660

gcaacguacu gaucuuugac cucgggggcg gcacguucga ugugaguguc cugagcauug      720

acgcgggggu guuugaagug aaggcaacug ccggugauac ccauuugggc ggggaggacu      780

ucgacaauag gcuggucaac cacuuuaugg aggaguuccg gcgcaaacau ggcaaggauc      840

ucuccgguaa uaagagggcc cugcggcgcc ugaggacugc augcgagcgg gccaaacgca      900

ccccgagcag uuccacccag gcgacuuugg aaaucgacag ccucuucgag ggcguggauu      960

uuuauaaguc cauuacgagg gcccgguucg aagaacugug uagugaccug uuuaggagca     1020

cccucgagcc cguagaaaaa gcacugcgcg augccaaguu ggacaaagca cagauccacg     1080

auuucgugcu ggguggcggg cuccacuccc auccacaggg ugccgagguc gccgcaggcc     1140

ugcugcaacg gcagggggcc gaacaggagc accaacccug aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  6926
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt7)

<400>  6926
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaagggcc ccgccguggg gaucgaccug gguaccacuu      120

acuccugcgu cggcguguuc cagcacggga aaguagagau uaucgcaaac gaucaaggca      180

auaggaccac gccaaguuau guggccuuua cugacaccga acggcucauu ggugaugcgg      240

ccaagaacca ggucgcaaug aauccgacca acacuguguu cgacgccaaa cgccugaucg      300

ggaggcgguu ugaugacgca gugguccaga gcgauaugaa gcauuggccc uucauggugg      360

uaaaugacgc cggccgccca aaagugcagg ucgaguacaa gggcgaaacc aaguccuuuu      420

aucccgagga agugaguagc augguguuga cgaaaaugaa ggagauugcg gaggccuacc      480

uggggaaaac ugucaccaac gcagugguaa cugugccagc cuauuucaau gauucccaaa      540

ggcaggccac caaggacgca gguaccaucg ccggccucaa cguccugcgg aucauuaaug      600

aacccacggc ggccgcaauc gccuacgggu uggauaaaaa ggugggcgca gagcgcaacg      660

ugcugauuuu ugaccucggu gggggcacuu ucgaugucag cauccugacc auugaagacg      720

gcaucuuuga ggugaaaucc acugccgggg acacccaccu ggguggcgag gauuucgaca      780

auaggauggu aaaccauuuu auugccgaau uuaagcggaa gcacaaaaag gauaucagug      840

agaauaaacg cgcggugagg cggcuccgca ccgcauguga aagggccaag cggacucuga      900

gcuccagcac gcaggccagu aucgagauug acuccuugua ugaagggauc gauuucuaca      960

ccagcauuac ucgcgcaagg uuugaggagc ugaacgccga ccucuuccgg ggcacccugg     1020

auccagucga aaaagcgcug cgcgacgcca aguuggauaa gucccagauc caugacauug     1080

ugcucgucgg uggcaguacc aggaucccga aaauccaaaa gcugcugcag gauuucuuca     1140

augggaaaga gcucaacaag agcauuaacc ccgacgaagc aguggccuac ggcgcagccg     1200

ugcaggccgc aauccugucc ggggacaaaa gcgagaaugu acaggauuug cugcuccugg     1260

acgugacucc acugaguuug gguauugaaa cggccggcgg ggucaugacc gugcucauca     1320

agcggaacac uaccauuccc accaagcaaa cucagacguu uaccacuuau uccgauaauc     1380

agccaggcgu ccugauccaa guguacgagg gugagagggc gaugaccaaa gacaacaauc     1440

ugcucggcaa guucgaacug acugggauuc ccccggcacc ccgcggcgug ccacagaucg     1500

agguaaccuu ugauaucgac gccaacggga uuuugaaugu gagcgccguc gauaaaagua     1560

cgggcaagga aaacaaaauc accauuacua augacaaggg ucggcugucc aaggaggaua     1620

ucgaaaggau ggugcaggag gccgagaaau auaaggcaga agacgagaaa cagcgcgaua     1680

aggucagcag caaaaacucc cucgaaaguu acgcguucaa uaugaaggcc accguggagg     1740

acgagaaacu gcaagggaag auuaacgaug aagacaagca gaaaauccug gacaagugca     1800

augagaucau uaacugguug gauaaaaauc agacugcaga aaaggaggaa uuugagcacc     1860

agcaaaaaga gcucgaaaag guguguaacc ccaucauuac caagcuguau cagagcgccg     1920

gcgguaugcc aggcgggaug cccggcgggu ucccaggcgg uggggccccg cccuccggcg     1980

gcgcaagcag ugggccaacg aucgaggaag uagacugagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  6927
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt7)

<400>  6927
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucagcgccu ccagggcagc cgcggcccgg cuggugggcg      120

cagccgcaag ucgcgggccc accgccgcga ggcaccagga cagcuggaac ggucucuccc      180

augaggccuu ccggcugguc agucgcaggg auuacgcaag cgaagccauu aagggcgccg      240

ugguagggau cgacuugggc acuaccaauu ccugcguggc agucauggag gguaaacaag      300

ccaaggugcu ggaaaacgcg gagggggccc ggacgacucc aagcgugguc gcauuuaccg      360

ccgauggcga acgccucgug ggcaugccgg caaaaaggca ggccguaacc aaucccaaca      420

auacuuucua ugccaccaag cggcugauug ggcgcaggua cgacgaucca gaggugcaga      480

aagacaucaa gaacgucccc uuuaagauug ugcgggcguc caauggugau gcaugggugg      540

aggcccacgg caaauuguau aguccaagcc agaucggggc cuucguccug augaagauga      600

aagaaacggc agagaacuac cucggccaua cugccaagaa ugcggugauc accguacccg      660

ccuauuuuaa cgacucccaa cgccaggcaa cuaaagaugc cggucagauu agcgggcuga      720

augugcugag ggucaucaac gaaccaaccg cagccgcccu cgcauacggc cuggacaaga      780

gugaggauaa agugauugcc guguaugacu ugggcggggg uaccuucgau aucuccauuc      840

uggagaucca gaagggcguc uuugaaguaa agagcacgaa uggggacacu uuccucggcg      900

gugaggacuu ugaucaagcg cugcugcggc acauugugaa agaguucaag cgcgaaaccg      960

gcguggacuu gacuaaagau aacauggccc uccagagggu ccgggaagca gccgagaagg     1020

ccaaauguga gcuguccagu agcgugcaga ccgacaucaa ucugccguac cucaccaugg     1080

auuccagcgg gcccaagcau cugaacauga aguugacucg cgcacaguuu gaaggcaucg     1140

ucacggaccu gauuaggcgg accaucgcgc caugccaaaa agccaugcag gaugcagagg     1200

ugaguaaguc cgacauuggg gaagugaucc ucguaggugg caugacuagg augcccaaag     1260

ugcagcaaac cguccaggau cuguucgggc gcgccccaag caaggccgug aaccccgacg     1320

aggcagucgc cauuggcgcg gccauccagg guggcgugcu ggcaggggau gugaccgacg     1380

uauugcuccu ggacgugacu ccgcugaguc ucggcaucga aacgcugggc ggggucuuca     1440

ccaaauugau uaaucggaac acuaccaucc ccaccaagaa gucccaggug uuuagcacug     1500

ccgccgaugg ucaaacgcag gucgagauua aaguguguca gggggagagg gaaauggcag     1560

gcgacaauaa gcugcucggu caguucaccc ugaucggcau uccacccgcc ccacgcgggg     1620

ugccccaaau cgagguaacu uuugauaucg acgcgaacgg cauuguccac gugagcgcca     1680

aagauaaggg gaccggccgg gaacagcaga ucgugauuca guccaguggu gggcugagca     1740

aagacgauau cgagaauaug gucaagaacg cagaaaagua cgccgaggag gacaggcgca     1800

aaaaggaacg gguggaggca gugaauaugg ccgaaggcau uauccacgau acugagacca     1860

aaauggagga guucaaggac caauugccag cggaugaaug caacaaacuc aaggaagaga     1920

uuuccaaaau gagggaacug cuggcccgga aggacagcga gacgggcgag aauauccgcc     1980

aggcagccag uucccuccag caggccagcc ugaaguuguu ugaaauggca uauaaaaaga     2040

uggccuccga gagggaaggg agugguagcu ccggcaccgg ggagcaaaaa gaagaucaga     2100

aggaggagaa acagugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  6928
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt7)

<400>  6928
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg aggcaggcgg gagcgauggu cccagggaaa      120

ccgccccaac uuccgcguac aguagcccgg cccggucccu gggcgacacc gggaucacgc      180

cccucagucc aagccacauu gugaacgaua cugacuccaa ugucagcgag cagcaauccu      240

uccugguggu aguggcaguc gauuuuggca ccaccaguag cgguuaugcc uacuccuuca      300

cuaaagaacc cgagugcauc caugugauga ggcgcuggga agggggcgac ccaggcguga      360

gcaaccagaa gacccccacg acuauuuugc ugaccccaga gcggaaauuu cacaguuucg      420

gguaugcagc ccgcgauuuu uaccaugacc ucgauccgaa ugaggcgaag caguggcugu      480

auuuggaaaa auucaagaug aagcugcaca cuaccgguga ccucaccaug gauacggacc      540

ugacugccgc aaacggcaaa aaggucaaag cccuggagau cuuugccuac gcacuccagu      600

auuucaagga acaagcccug aaagaguugu ccgaucaggc ggggagcgag uuugaaaauu      660

ccgacgugag guggguaauu accgugcccg ccaucuggaa gcagccagca aaacaguuca      720

ugcggcaagc cgcauaccag gccggccugg ccagucccga gaacagcgaa cagcucauca      780

uugcgcugga gccagaagca gccuccaucu acugucgcaa gcugagguug caucagauga      840

uugagcucag caguaaggcc gcagucaaug guuauuccgg gagcgacacu gugggcgccg      900

gcuuuaccca agcgaaagag cacauccggc gcaacaggca gagucggacc uuccuggugg      960

aaaaugucau uggggagauc ugguccgaac uggaggaagg ugauaaguac gugguagugg     1020

acagcggcgg gggcacuguc gaucucacgg ugcaccagau ucgccugccc gagggucauu     1080

ugaaagagcu guauaaggcc accggcgggc cguacggcag ccucggggug gacuaugagu     1140

ucgaaaaacu gcuguacaag aucuuuggug aagauuucau cgagcaauuu aagauuaaaa     1200

ggcccgcagc cugggucgac uugaugaucg cauucgaauc ccggaagcgc gccgccgcac     1260

cagauaggac uaacccccuc aauauuaccc ugccauuuag uuucaucgac uauuacaaaa     1320

aguuucgggg ccacagcgug gagcaugccc ugcgcaaauc caacguagau uucgugaagu     1380

ggagcaguca ggggaugcuc aggauguccc ccgacgcgau gaaugcccug uuuaagccaa     1440

ccauugauag caucaucgag cacuugcggg accuguucca gaaaccggaa gucuccacug     1500

ugaaguuucu cuuccugguc ggcgguuuug cagaggcacc ccuguugcag caagccgugc     1560

aggccgcguu cggcgaccag ugcaggauua ucauuccaca ggaugugggg cucacgaucc     1620

ugaaaggcgc cguacuguuc gggcucgacc ccgcagugau uaagguccgc cggaguccac     1680

ugaccuacgg cguggguguc uugaacaggu auguggaagg gaaacauccc ccggagaagc     1740

ugcucgugaa ggauggcacu cgcuggugua ccgacguauu ugauaaauuc aucagcgccg     1800

accaauccgu ggcccugggu gagcugguca agcggagcua caccccagca aaacccaguc     1860

aguuggugau cgucauuaau aucuauucca gcgaacacga uaacgugucc uuuauuacug     1920

accccggcgu gaagaaaugc gggacgcuga ggcucgaucu gaccggcacc agugggacug     1980

ccguaccagc gcgccgggag auccagacuc ucaugcaguu cggcgacacc gaaauuaagg     2040

ccacggcaau cgauauugcc accagcaaau ccgucaaggu ggguaucgac uuucugaacu     2100

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  6929
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt7)

<400>  6929
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuggccgugc ccgagauggg ccuccagggg cuguacaucg      120

guagcucccc agaaaggagu ccggucccca gcccacccgg cuccccacgg acccaagaga      180

guugcgggau ugcacccuug acuccaagcc aguccccgaa gcccgaagug cgcgccccac      240

agcaggcgag cuucuccgua guggucgcca ucgacuuugg caccacgagu agcgguuaug      300

cauucuccuu ugccagcgau cccgaggcaa uucacaugau gaggaaaugg gaagggggcg      360

acccaggcgu ggcccaucaa aagacuccca ccugucugcu ccugaccccg gagggggcgu      420

uccacaguuu ugguuacacu gcccgggauu auuaccauga cuuggauccc gaggaagcac      480

gcgacuggcu guauuucgag aaauuuaaga ugaaaaucca cuccgccacc gaucucacgc      540

ugaagacuca gcuggaagcc gugaacggca agaccaugcc agcacucgag gucuucgccc      600

augcgcugag guuuuuccgg gagcacgccu ugcaggaacu gcgcgagcag agccccuccc      660

ucccagaaaa agacacugug agguggguac ugaccgugcc cgcaauuugg aagcaaccag      720

ccaaacaguu uaugcgggag gcagccuacc uggccggguu ggucagucgc gaaaaugcgg      780

agcagcuccu gaucgcacug gagccggaag ccgccagcgu guauugcagg aagcuccggc      840

ugcaccaguu gcuggaucuc uccggccgcg cacccggugg gggcaggcug ggcgagcggc      900

gcagcaucga caguuccuuc aggcaagccc gggaacagcu gcgcaggagc cggcauagua      960

ggaccuucuu gguggagucc ggggucggug aacucugggc ggagaugcag gccggcgauc     1020

gcuacguggu agcagacugu gggggcggua cgguggaucu gacuguccac caacuggagc     1080

agccacaugg cacccucaaa gaacuguaca aggccagcgg gggccccuau ggggcagugg     1140

guguggacuu ggccuuugag cagcugcucu gccggauuuu cggcgaagac uuuaucgcca     1200

cuuucaaaag gcagcgccca gcagccuggg ucgaucugac cauugcguuu gaggcccgga     1260

agaggaccgc agggccccac cgcgccggcg cccugaacau cagcuugccg uucuccuuua     1320

uugacuucua ccggaagcaa aggggucaca auguggaaac ugcacuccgg cgcaguagcg     1380

uaaacuuugu gaaauggucc agccagggca ugcugaggau gaguugugag gcgaugaaug     1440

agcuguucca gccaacgguc uccgggauca uucagcauau cgaagcccuc cuggcacggc     1500

ccgaggugca aggcgucaag uugcuguuuc ucguaggggg cuucgccgaa agcgccgugc     1560

ugcagcacgc agugcaggcc gcgcugggug cccgcggguu gagggugguc gugccccaug     1620

augucggccu gaccauccuc aaaggugcag ugcuguuugg ccaggcccca ggggugguac     1680

gggugcgcag gaguccccuc acuuauggcg ucggggugcu gaaccgguuc gucccaggca     1740

ggcacccgcc cgagaaguug cuggugcgcg acggucggag guggugcacc gauguguucg     1800

agcgcuuugu agccgcagaa caauccgucg cccucgggga ggaagugcgg aggagcuacu     1860

guccagcgcg ccccggccag cggagggugc ugauuaaucu guauugcugu gccgcagagg     1920

acgcccgcuu caucaccgau ccaggcgucc ggaaaugcgg ggcauugucc cuggaacucg     1980

agcccgccga cugcggucag gauacugcgg gcgccccgcc agggaggcgc gagauucggg     2040

cagccaugca guuuggcgac acggaaauca aggugaccgc cguggaugua agcacuaaca     2100

ggaguguccg cgcauccauu gacuuccuga gcaauugagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  6930
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt7)

<400>  6930
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagggaga ugaccauccu gggcagcgca gugcucacuc      120

uguugcuggc cggguaccuc gcgcagcaau aucugcccuu gccaaccccg aaggucauug      180

guaucgaccu gggcacgacu uacugcuccg uggggguauu cuuucccggc accgguaaag      240

ugaaggucau uccagaugaa aacgggcaca ucaguauucc cagcauggug uccuucaccg      300

acaaugaugu guaugucggc uacgagagug uggaacucgc cgacagcaac ccacagaaua      360

cuaucuauga ugcaaaacgg uuuaucggca agauuuucac cgccgaggaa cuggaggcag      420

agaucgggcg cuaccccuuu aaaguacuga acaagaaugg uaugguggag uucuccguca      480

cgagcaacga aacuauuacc guguccccag aauauguggg caguaggcuc cuguugaagc      540

ugaaagagau ggccgaggcg uaccucggga ugccggucgc caaugcagug aucagcguac      600

ccgccgaauu ugaccugaag cagcggaacu ccacuauuga ggccgcaaau cuggccggcu      660

ugaaaauccu ccgcgugauu aacgaaccaa ccgcggccgc aauggccuac ggucugcaua      720

aggcagaugu cuuccacgug cuggugaucg accucggggg cggcacccug gaugucagcu      780

ugcugaauaa acaagggggu auguuucuca cgagggccau gaguggcaac aauaagcucg      840

ggggccagga cuucaaccag cggcuguugc aguaucucua caaacagauc uaucaaacuu      900

acgguuuugu gcccucccgc aaggaggaaa uucauaggcu gcggcaggcc guagagaugg      960

ugaagcugaa ucucacccug caccagagcg cgcaguuguc cguccugcuc acuguggagg     1020

aacaagaucg caaagagcca cauaguagcg acaccgaacu gcccaaggau aaacugucca     1080

gcgcagacga ccacaggguc aacaguggcu ucgggcgggg cuuguccgau aagaaaagcg     1140

gggagaguca ggugcuguuc gaaaccgaga ucucccgcaa gcuguuugac acucugaacg     1200

aggaucucuu ccagaagauu cuggugccga uccaacaggu auugaaagaa ggucaccugg     1260

agaagacgga aauugacgag gugguccucg ugggcgggag caccaggauc ccccggaucc     1320

gccaggucau ucaggaauuu uucggcaaag auccaaauac uagcguggac cccgaucugg     1380

ccgugguaac cgguguggcc auccaagcag gcauugacgg gggcuccugg ccacugcagg     1440

ucagugccuu ggagaucccc aacaagcauc ugcagaaaac caauuuuaac ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6931
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt7)

<400>  6931
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgcaaucg gcgugcaccu ggggugcacc agcgccugug      120

ucgcggugua caaggacggu agggccggcg uaguggcaaa cgaugccggg gaccggguca      180

cucccgcagu gguggccuau uccgagaaug aagagauugu cggccucgcg gccaaacaga      240

gucgcaucag gaacauuagc aauaccguga ugaagguaaa acaaauccug ggucggucca      300

guagcgaucc acaggcacag aaguacauug ccgaauccaa augcuuggug aucgagaaga      360

acgggaagcu gcgcuaugaa aucgacacgg gcgaggagac uaaauucguc aauccggaag      420

auguggccag gcucauuuuu agcaagauga aagagaccgc acauuccgug cugggcagug      480

acgccaacga ugucgugauc accguacccu ucgacuuugg ggaaaagcag aaaaaugcgu      540

ugggugaggc cgcacgggcc gcaggcuuca acgugcugcg ccucauucac gagccaagcg      600

ccgcccugcu ggcguacggg aucggccaag auucccccac ugguaagagc aauauucucg      660

ucuuuaaacu gggcgggacc aguuuguccc ugagcgugau ggaagugaac uccggcaucu      720

auaggguccu caguacgaau acugacgaua acauuggggg ugcacauuuc accgagacuc      780

uggcccagua ccuggccagc gaauuucagc gguccuucaa gcacgacgug cgcggcaaug      840

caagggccau gaugaaguug accaacagcg cggagguagc caaacauagu cucuccaccc      900

uggggagcgc aaauuguuuu cuggauaguc ucuaugaagg ccaggacuuc gacugcaacg      960

ugucccgggc ccgcuuugag cuguugugua gcccacuguu caacaagugc aucgaggcaa     1020

ucaggggucu ccuggaucaa aauggcuuca cggccgacga uauuaacaaa gucgugcugu     1080

gugggggcag cucccggauc cccaaguugc agcagcucau uaaagaccug uuuccagccg     1140

ucgaacugcu caauaguauc ccgcccgaug aggugauucc aaucggggca gccaucgaag     1200

cggguauucu gaucggcaag gagaacuugc ugguggaaga cagccucaug auugagugcu     1260

ccgcccgcga uauccuggua aagggggugg acgagagcgg cgcaaguagg uucacugucc     1320

uguuucccuc cgguacccca uugcccgccc ggcgccagca cacucuccaa gccccgggca     1380

gcauuuccag ugugugucug gaacuguacg agagcgaugg gaaaaauucc gcaaaggaag     1440

agaccaaauu cgcgcagguc gugcuccagg accuggauaa gaaagaaaac ggcuugaggg     1500

acauccuggc cgugcucacc augaagcggg acgggagccu gcacguaacu ugcacggauc     1560

aagagaccgg caagugcgag gcaaucagua uugaaaucgc cuccugagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  6932
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt7)

<400>  6932
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguggucg gccuggacgu ggggucccag aguugcuaca      120

ucgccguagc aagggccggu ggcauugaaa ccaucgcgaa cgaguucagc gaucggugua      180

cucccuccgu gauuaguuuu gggagcaaga aucgcaccau cggcgucgcc gccaaaaacc      240

aacagauuac gcacgcaaau aacacugugu ccaauuucaa gagguuucau ggucgggcau      300

ucaacgaccc auuuauccag aaagagaagg aaaaucucag cuaugaucug gugccguuga      360

aaaacggggg cgucggcauc aaggugaugu acauggggga ggaacaccug uucuccguag      420

agcagauuac cgccaugcuc cugaccaagu ugaaagagac ugcggaaaau agucugaaga      480

aacccgugac cgacugcguc aucagcgugc cauccuuuuu cacggaugcc gagcgcagga      540

gcgugcucga cgcagcccaa auugucgguc ugaacugucu gcggcucaug aaugauauga      600

cugccguggc acugaacuau ggcaucuaca agcaggacuu gcccagucug gaugaaaaac      660

cacgcauugu aguguuuguc gacauggggc auuccgccuu ccaggugagc gcgugcgccu      720

uuaauaaggg caaacucaag gugcugggua ccgcauucga ucccuuccug ggcgggaaga      780

acuuugacga gaaauugguc gagcacuucu gugccgaauu uaagacuaaa uauaagcucg      840

augcaaaauc caagaucagg gcccugcugc ggcucuacca ggagugcgaa aagcugaaaa      900

aguugaugag uagcaauucc accgaccugc cacucaacau ugaguguuuc augaacgaca      960

aagaugugag cggcaagaug aaucgcaguc aauuugaaga acugugcgcc gagcuguugc     1020

agaaaaucga aguaccgcuc uauucccugc uggagcagac ccaucucaag guggaagacg     1080

ucagcgcggu ggagaucguc gggggugcaa cgaggauucc cgccgugaag gaacggaucg     1140

ccaaauucuu uggcaaggau auuaguacua cccugaacgc agacgaggcc guggcgcgcg     1200

ggugugccuu gcagugcgca auccuguccc cagccuucaa aguaagggag uuuagcguga     1260

cugaugcagu ccccuuccca auuagccuca ucuggaauca cgacuccgaa gauaccgagg     1320

gcgugcacga agucuuuagu cggaaccaug ccgcccccuu cagcaaggug cugaccuuuc     1380

ugcgcagggg uccguucgag uuggaagcau ucuacuccga cccccaaggc gugccauacc     1440

ccgaggccaa aaucgggcgg uuuguagugc agaaugucag cgcgcagaag gauggcgaga     1500

agagucgcgu gaaagucaag gugaggguga acacucacgg gauuuucacg aucuccaccg     1560

ccagcauggu agaaaaaguc ccaacugagg aaaaugagau guccagugag gcagacaugg     1620

aaugccucaa ccaacggccc ccagagaauc cggauaccga caagaacgug cagcaggaca     1680

auagcgaagc cgguacccag ccccaagugc agacugaugc ccagcagacg ucccaaagcc     1740

cacccagucc agagcugacc uccgaagaga acaaaauucc cgacgcagau aaggcgaaug     1800

agaaaaaggu cgaccagccg ccagaagcca agaaacccaa gaucaaagug gugaacguag     1860

agcugcccau ugaagcaaau cucgucuggc agcugggcaa ggauuugcug aacauguaua     1920

ucgagacuga agggaaaaug aucaugcagg acaagcucga gaaggagagg aacgaugcca     1980

aaaaugccgu ggaagaguac guguaugaau uucgcgacaa gcuguguggc ccauacgaga     2040

aauucauuug cgaacaagau caucagaacu uucugcgguu gcugaccgag accgaggacu     2100

ggcucuauga agagggugaa gaucaggcaa agcaggccua cgucgacaaa cuggaggagc     2160

ucaugaagau cggcacuccc gugaagguaa gguuccaaga agcggaggaa cgcccaaaaa     2220

uguuugagga acuggggcag cgguugcagc acuaugccaa gauugcagcc gauuucagga     2280

auaaagacga gaaguacaac cacaucgacg agagcgaaau gaaaaaggug gagaaauccg     2340

ucaaugaagu gauggagugg augaacaaug ugaugaacgc ccaagcaaag aagagucugg     2400

aucaggaccc ggucgugcgc gcccaggaaa uuaaaacgaa gaucaaagag cucaauaaca     2460

ccugugagcc cguagugacu cagccaaagc ccaaaauuga aagcccaaag cuggagcgga     2520

cccccaaugg cccgaacauc gauaagaaag aagaggaccu ggaggauaag aauaacuuug     2580

gggcggaacc accccaucaa aauggcgagu gcuacccaaa cgagaaaaac uccgucaaua     2640

uggacuugga uugaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  6933
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt7)

<400>  6933
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaagg ugaggcggca gcgccccagg cggcgcgucu      120

gcugggcacu gguggccgua cuccuggcgg auuugcuggc ccucagcgac acccuggcag      180

ugauguccgu cgauuugggc agugagagca ugaaaguggc caucgugaag ccaggggucc      240

cgauggaaau ugugcugaac aaagagucca ggcggaagac ucccguaauc gugacccuca      300

aagaaaauga gcgcuucuuu ggugacagug cagccagcau ggcgauuaag aacccaaagg      360

ccacgcugag guacuuccaa caucugcucg gcaaacaggc agauaauccc cacgucgccc      420

uguaucaggc ccgguuucca gaacacgagu ugacuuucga cccccagcgc caaaccgugc      480

auuuucagau cuccagccag cugcaguucu ccccagagga agugcucggg augguccuga      540

acuacaguag gagccuggca gaggauuuug ccgaacaacc gauuaaggac gcggugauca      600

ccguacccgu guucuuuaau caggccgagc ggcgcgcagu cuugcaggcc gcaaggaugg      660

ccggccucaa agugcugcag cugaucaacg auaauacugc caccgcgcuc uccuauggug      720

uguuccggcg caaggacauu aacacgacug cacaaaauau cauguuuuac gauaugggga      780

gcggcaguac cgucuguacu auugugaccu aucagauggu aaaaaccaag gaggccggca      840

ugcagccaca acugcagauc aggggugugg gguucgaccg gacguugggc gggcuggaaa      900

uggagcuccg ccugagggaa cggcuggccg gcuuguucaa cgagcagagg aaaggucagc      960

gcgcaaagga uguccgggaa aaucccaggg ccauggcgaa gcuccugcgc gaggccaacc     1020

ggcugaaaac ugugcucucc gcaaaugccg accacauggc acaaauugag gggcugaugg     1080

acgaugucga cuuuaaggcc aaagugacca ggguggaguu cgaggaauug ugcgccgauc     1140

uguuugagcg cguaccaggc cccgugcagc aggcacucca gagcgccgaa augucccugg     1200

acgagaucga gcaagucauu cuggugggcg gggcgacucg ggucccgagg gugcaggaag     1260

uguugcucaa ggccguaggu aaagaggaac ugggcaagaa caucaaugca gaugaggccg     1320

ccgcaauggg ggcgguguac caggccgcag cccugaguaa ggccuucaaa gucaagcccu     1380

uugugguccg ggacgcagug guguauccaa uccucguaga guucacccgc gaggucgagg     1440

aagaacccgg cauucauagc cugaaacaca acaagagggu guuguuuucc cggauggguc     1500

cauaccccca gcgcaaagug aucaccuuca acagguacag ccacgauuuu aauuuccaua     1560

uuaacuaugg cgaccugggg uuucucggcc cagaagaucu gcgggucuuc gggagucaaa     1620

aucugacuac ggugaaguug aagggugugg gcgacuccuu uaaaaaguac ccggauuaug     1680

agagcaaagg gaucaaggcc cacuucaacc uggacgagag uggcguacuc ucccuggacc     1740

gcgucgaaag cguguucgag acccucgugg aagauagcgc ggaggaagag uccacucuga     1800

ccaaauuggg uaauaccauu aguagccugu uuggcggggg cacuacgccc gacgccaagg     1860

agaacgggac cgauacuguc caggaagagg aagagucccc agcagaaggc agcaaggacg     1920

agcccgguga acagguggaa cucaaagagg aagccgaggc cccaguagaa gaugggaguc     1980

agcccccgcc acccgagccc aagggcgacg caaccccaga gggugaaaaa gccaccgaga     2040

aggaaaaugg cgauaaaucc gaggcgcaaa agcccagcga gaaagccgaa gcagggccag     2100

agggcguggc cccggcaccc gaaggggaga agaagcagaa accagccagg aagcggagga     2160

uggucgaaga gaucggcgug gagcuggugg uccuggacuu gcccgaucug ccagaagaca     2220

aacucgcgca guccgugcaa aagcugcagg aucucacucu gcgcgacuug gagaaacagg     2280

aacgggagaa ggccgcaaac agucuggaag ccuucaucuu ugagacgcag gauaagcugu     2340

accaacccga guaucaggaa guaagcaccg aggaacagag ggaggagauu uccgguaaac     2400

ucagcgccgc aaguacuugg cuggaagacg aggggguggg cgccaccacu gucauguuga     2460

aggaaaaacu ggcggagcuc cgcaagcugu gucagggccu cuucuuucgg guggaagaga     2520

ggaaaaagug gccggagcgc cuguccgccu uggacaaucu gcugaaccau agcuccaugu     2580

uccucaaggg ggcacggcug aucccagaaa uggaucaaau uuuuaccgag guggaaauga     2640

cgaccuugga gaaagucauc aaugaaacuu gggccuggaa gaacgcaacc cuggccgagc     2700

aggccaaacu ccccgcaacu gagaagccag ugcugcugag uaaagacauu gaagcgaaga     2760

ugauggcccu cgauagggag guacaguacc uguugaauaa agccaaguuc accaagcccc     2820

gcccgcggcc caaagacaag aacgguacga gggcagaacc accccugaau gccagcgcau     2880

ccgaucaggg cgagaaagug aucccacccg ccgggcaaac cgaagacgcg gagccaauca     2940

gcgagccgga aaaggucgag acuggcagug aacccgguga uaccgagcca cucgagcugg     3000

gcgggcccgg cgccgaacca gagcagaaag aacaguccac ugggcaaaag cgccccuuga     3060

agaacgacga gcugugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6934
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt7)

<400>  6934
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaaa cccagacuca agaccagcca auggaggaag      120

aggaagugga gaccuucgcc uuucaggcag agaucgccca gcugaugagc cucauuauca      180

acacguucua cuccaauaag gaaauuuuuc ugagggaguu gaucaguaac agcuccgaug      240

cgcuggacaa aauucgguau gaaagucuca cugauccgag caagcuggac uccggcaaag      300

aguugcacau caaucugauc cccaacaagc aagaucgcac ccucaccauu gucgacacug      360

ggaucgguau gaccaaagcc gaucugauua auaaccuggg cacgaucgca aagagcggga      420

cuaaggccuu cauggaggca cuccaggccg gcgcggacau uuccaugauc ggucaguuug      480

gggugggcuu cuacagugcc uaucugguag cagaaaaagu gaccgucauu acuaagcaua      540

augaugacga gcaguacgcc ugggaaagcu ccgccggcgg gagcuuuacc gugaggaccg      600

auacggguga gccaaugggc cgggggacua aagugaucuu gcaccugaag gaagaccaaa      660

ccgaguaucu cgaggaacgc aggaucaaag agauugucaa gaaacauagu caguucaucg      720

gcuaccccau uacucuguuu guggaaaagg agcgggauaa ggaaguaucc gacgacgagg      780

cagaggaaaa agaggauaag gaagaggaaa aagagaagga ggaaaaagag agcgaagaca      840

agccagagau cgaggaugug gguuccgacg aagaggaaga gaagaaagau ggggacaaga      900

aaaagaaaaa gaagauuaaa gaaaaguaua ucgaucagga ggagcugaac aaaaccaagc      960

ccaucuggac ccgcaaucca gacgauauua cuaacgaaga guacggcgag uucuacaaaa     1020

guuugacgaa ugacugggag gaucaccucg ccgucaagca uuuuagcgug gaaggccagc     1080

uggaguucag ggcgcuccug uucgugccgc ggcgcgcccc cuuugaccug uucgagaaca     1140

ggaagaaaaa gaauaacauc aaauuguaug uccggcgcgu guuuauuaug gacaauugcg     1200

aagaacugau cccagaauac cucaacuuca uuaggggugu aguggauucc gaggaccugc     1260

cccugaacau cagccgggaa auguugcaac agaguaagau ccucaaaguc auucgcaaga     1320

aucuggugaa aaagugucug gagcucuuua ccgagcuggc agaagauaag gagaacuaua     1380

aaaaguucua cgaacaguuu uccaaaaaua ucaaguuggg gauucacgag gacagccaaa     1440

acaggaaaaa gcugagugag cuccugcggu auuacacuuc cgccagcggc gaugaaaugg     1500

ugagccugaa ggacuauugc acccgcauga aagagaauca gaagcacauc uacuacauua     1560

ccggggaaac uaaagaucag gucgcaaacu ccgccuucgu ggagagguug cggaagcaug     1620

gccucgaagu aaucuauaug auugagccaa ucgacgagua cugugugcag caacugaaag     1680

aauuugaggg uaagacgcug gucaguguga ccaaggaagg ccucgagcug cccgaagaug     1740

aggaggagaa aaagaaacag gaagaaaaga aaacuaaguu cgagaauuug ugcaaaauca     1800

ugaaggacau ucuggagaag aaagucgaaa aggugguggu aagcaacagg cucgugaccu     1860

ccccguguug caucgucacc agcacuuaug gguggacggc caauauggag cgcauuauga     1920

aagcgcaggc acugcgggau aacaguacca ugggcuacau ggccgccaag aaacaccugg     1980

aaaucaaucc cgaccauucc auuaucgaga cuuugaggca gaaggcagaa gccgauaaga     2040

acgacaaaag cgugaaggac cuggucaucc uccuguauga gaccgcgcuc cuguccagug     2100

gguuuagcuu ggaggaucca caaacucacg ccaaucgcau uuaccggaug aucaaacugg     2160

gucucggcau ugacgaagau gaccccaccg cagaugacac guccgccgca gugaccgagg     2220

aaaugccacc ccuggagggg gaugacgaua cuagcaggau ggaagaggug gacugaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  6935
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt7)

<400>  6935
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucca agcuggauag uggcaaaggg cuccacauca      120

accuggugcc caauaagcag aaccaaaccu ugacuauugu cgacaccagg aucgguauga      180

cgaaaacuga ucugauuaau aaccucggca ccgugaccaa gagcgggacu aaagccuuca      240

uggaggcacu gcaggccgac gcggauaucu ccaugauugg ccauuuuggu guaggguucu      300

acagugccua uuugguggca aagaagguca ccgugaucag caaacacaau aacgacgaac      360

aguacacgug ggaguccagc gccggcggcu ccuuuacugu gcggaccgau gaaugaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  6936
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt7)

<400>  6936
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaag ugcaccaugg cgaggaagag gucgaaaccu      120

ucgccuuuca ggcagagauc gcccaacuga ugagccucau uaucaacacu uucuacucca      180

auaaggagau uuuucugagg gaauugauca guaacgcgag cgacgcccug gauaaaauuc      240

gguaugaguc ccucaccgac ccaaguaagc uggauagcgg gaaagaauug aagaucgaca      300

ucauuccgaa uccccaggag cgcacgcuga cucucgugga uaccgguauc ggcaugacca      360

aagcagaccu gauuaacaau cuggggacua ucgccaaguc cggcaccaag gcauucaugg      420

aggcccucca ggcgggugcc gauauuagca ugaucgggca guuuggcgua ggcuucuacu      480

ccgcauaucu gguggccgaa aaagucgugg ugauuacgaa gcacaacgac gaugagcaau      540

acgccuggga aaguagcgca ggggguuccu uuacugucag ggccgaccau ggcgagccaa      600

ucgggcgggg caccaaagug aucuugcacc ugaaggaaga ucagacugag uaucucgagg      660

aacgcagggu aaaagaggug gucaagaaac auagccaguu cauugguuac cccaucaccc      720

uguaucugga aaaggagcgg gaaaaggaga uuagugacga ugaggcggaa gaggaaaaag      780

gggagaagga agaggaggac aaagacgaug aagagaagcc aaaaaucgaa gacgugggcu      840

ccgaugagga ggacgauagc ggcaaggaca agaaaaagaa aaccaagaaa auuaaggaaa      900

aguacaucga ucaggaggaa uugaauaaaa cgaagcccau cuggacucgc aacccagacg      960

auauuaccca agaggaauac ggggaguuuu auaaaucccu cacuaaugac ugggaggauc     1020

accuggccgu gaagcacuuc agugucgaag gucagcugga guuuagggca cuccuguuca     1080

ucccgcggcg cgcccccuuc gacuuguuug aaaacaaaaa gaagaaaaau aacauuaagc     1140

uguacgugag gcggguauuc aucauggaca gcugcgauga gcucauucca gaauaucuga     1200

auuuuauccg cggcgugguc gacuccgagg aucugcccuu gaacaucagc agggagaugc     1260

uccagcagag uaaaauucug aaggugaucc ggaaaaauau ugugaagaaa ugucuggaac     1320

ucuucuccga gcuggcagaa gacaaggaga acuacaagaa auuuuaugaa gccuucagca     1380

agaacuugaa acuggggauc caugaggaua guaccaaucg caggcggcuc uccgagcugc     1440

ugcgcuacca caccagccaa agcggcgacg aaaugacuuc cuugagugag uaugucagca     1500

ggaugaagga aacgcagaaa uccauuuacu acaucaccgg ugagagcaag gaacaggugg     1560

ccaacagugc guuuguagag cgggugagga agcgcggcuu cgaggucgug uauaugacug     1620

aaccaauuga ugaguacugc guccaacagc ucaaagaauu ugacgggaag ucccugguga     1680

gcgugaccaa agagggccug gagcuccccg aagaugagga agagaagaaa aagauggaag     1740

aguccaaggc aaaauucgag aaucugugua aguugaugaa agaaauccug gacaagaaag     1800

uagagaaggu gaccaucagu aaccggcucg ucagcucccc gugcuguauu gugacuagca     1860

cguaugggug gaccgccaau auggaaagga ucaugaaagc ccaggcacug cgcgauaaca     1920

guacuauggg uuacaugaug gccaagaagc aucuggagau uaaucccgac cacccaaucg     1980

ucgagaccuu gcggcagaaa gcggaagccg auaagaacga caaagcagug aaggaccugg     2040

ugguacuccu guuugagacc gcccuccugu ccagcggcuu cuccuuggaa gauccccaaa     2100

cucacaguaa uaggauuuau cgcaugauca aacuggggcu cggcaucgac gaggaugaag     2160

uggcagccga ggagccaaac gccgcagucc ccgacgaaau uccaccgcug gagggugaug     2220

aagacgccag ccggauggag gaaguggauu gaggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  6937
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt7)

<400>  6937
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agggcccugu gggugcucgg ccugugcugu gucuugcuga      120

ccuucgggag cgugcgggca gacgaugagg uagacgugga ugguacuguc gaagaggacc      180

ucggcaaguc ccgcgaaggg aguaggaccg augacgaggu ggugcagcgg gaagaggagg      240

ccauccaacu ggauggcuug aacgcgagcc agauucgcga acugagggag aaauccgaaa      300

aguuugccuu ccaggcagag gucaaucgga ugaugaaacu caucauuaac agucuguaca      360

agaauaaaga gaucuuucug cgcgaacuca uuagcaacgc cuccgacgca cuggauaaga      420

ucagguugau cagccugacg gacgagaaug cccucuccgg uaacgaagaa cugacuguga      480

agauuaaaug cgauaaggag aaaaaucugu ugcacguaac cgacaccggg gugggcauga      540

cucgggagga gcucgucaag aaccugggca ccaucgcgaa aagugggacg agcgaguucc      600

ugaauaagau gacugaggcc caggaagaug gucaauccac cagcgagcuc auuggccagu      660

uugggguggg cuucuauagu gcauuucugg uggccgacaa agucaucgug acuuccaagc      720

auaacaauga cacccagcac auuugggaaa gcgauuccaa cgaguucagu guaaucgccg      780

acccccgcgg uaauaccuug gggaggggca cgacuauuac ccuggugcuc aaggaggaag      840

caagcgauua ccuggagcug gacacuauca aaaacuuggu caagaaauau ucccaguuua      900

ucaauuuccc aauuuacgug uggagcagua agaccgaaac cguggaggaa ccgauggagg      960

aggaagaggc cgcgaaagaa gagaaggagg aauccgauga cgaggccgca gucgaagagg     1020

aagaggagga aaagaaaccc aagacuaaaa agguggagaa aacgguaugg gauugggaac     1080

ucaugaacga caucaagcca auuuggcaac ggcccagcaa ggagguggaa gaggaugagu     1140

auaaagccuu uuacaagagu uucuccaaag aaagcgacga uccaauggca uauauccauu     1200

ucaccgccga gggcgaaguc acuuuuaaga gcauucuguu cgugcccacc uccgccccac     1260

gcgggcuguu ugacgaguac gguaguaaaa agagcgacua caucaagcuc uaugucaggc     1320

ggguguucau caccgaugac uuucacgaua ugaugccgaa auaccugaac uucgugaagg     1380

gcguagugga cuccgaugac uugccccuga augucagccg cgaaacucuc cagcagcaua     1440

aacugcugaa ggugauuagg aaaaaguugg uccggaaaac gcucgauaug aucaagaaga     1500

uugcggacga uaaauauaac gacaccuuuu ggaaggaguu cgggacuaau aucaaacugg     1560

gcgugauuga ggaucacagu aaccgcacca ggcuggcaaa gcuccugcgg uuucagucca     1620

gccaccaucc aaccgacauc acuuccuugg aucaauacgu ggaaaggaug aaagagaagc     1680

aggacaagau cuauuucaug gccgguagua gccgcaaaga agccgagucc agccccuuug     1740

uagagcggcu gcucaagaaa ggcuacgaag ugauuuaucu gacggagcca gucgacgaau     1800

acuguaucca ggcacugccc gaguucgaug ggaagagguu ucaaaaugug gccaaagaag     1860

gcgucaaguu cgacgagagu gagaagacca aagaaucccg cgaggcggug gaaaaggagu     1920

ucgaaccguu gcugaacugg augaaagaua aggcccucaa agacaagauu gagaaagcag     1980

ugguaagcca gcggcugacu gagucccccu gcgcccucgu cgcaagucag uacgggugga     2040

gcgguaauau ggaaaggauc augaaggccc aggccuauca aaccggcaag gauauuucca     2100

cuaacuacua ugcaagccag aaaaagaccu uugagaucaa uccacgccac ccccugauuc     2160

gggacauguu gaggcggauc aaagaagaug aggacgauaa gacggugcug gaccucgccg     2220

ugguccuguu cgagaccgcg acucugcgca guggguacuu gcugccagau accaaagccu     2280

auggcgacag gaucgaacgg augcuccgcc ugucccucaa cauugacccc gaugcaaagg     2340

uggaggaaga accagaagag gagccggaag agacugccga agacaccacg gaggauaccg     2400

aacaggacga ggaugaggaa auggacgugg guacugauga ggaagaggaa accgccaagg     2460

agagcacugc agagaaagac gaacugugag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  6938
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt7)

<400>  6938
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccagggagc ugcgggcacu ccuguugugg ggccgcaggc      120

ugcggccccu ccugcgcgcc ccagcguugg ccgcagugcc cggggguaag ccgauccugu      180

gcccaaggcg gaccacugcc cagcucggcc cccgcaggaa cccagcaugg agccugcaag      240

ccgggcggcu guucuccacc cagacggcgg aagacaaaga ggaaccccuc cacaguauua      300

ucagcuccac ugagaguguc cagggcagca ccuccaagca ugaauuucag gccgagacca      360

aaaagcuguu ggauauugug gcacgcagcc uguacuccga gaaagaagua uucaucaggg      420

agcucauuag uaaugccagc gacgcccugg aaaagcugcg gcacaaguug guguccgaug      480

gucaagcacu cccagagaug gagauccauc ugcagacuaa cgccgaaaaa gggaccauca      540

cgauucagga cacuggcauc ggcaugaccc aggaggaacu ggucagcaau cucgggacua      600

uugcgcgcag ugguuccaag gccuuucugg augcauugca aaaccaggcc gaggcaagcu      660

ccaaaaucau uggccaguuc ggggugggcu uuuauagugc cuucauggug gccgacaggg      720

ucgaagugua cagccggucc gcggcaccgg guagccuggg guaucagugg cucagugaug      780

gcuccggcgu auuugagauc gccgaggcca gcggggugcg caccgguacc aagauuauca      840

uccaccugaa aagugacugu aaggaguucu ccagcgaggc aaggguccgg gaugugguga      900

cgaaauacag caauuuuguc uccuuccccc uguauuugaa cggccgcagg augaauacuc      960

uccaagccau uuggaugaug gacccaaagg augugcggga auggcagcau gaggaauuuu     1020

acagguaugu agcgcaggcc cacgacaagc cccgcuacac ccugcacuac aaaacugaug     1080

caccacugaa cauccggagu auuuucuaug ugcccgacau gaagccgagc auguucgacg     1140

ucuccaggga gcucgggagc aguguggccc uguacucccg caaaguguug auccaaacca     1200

aggcaaccga uauucugccc aaauggcucc gguuuaucag gggcgucgug gacagcgagg     1260

auaucccacu gaaucugucc cgcgaauugc uccaggagag ugcccugauu cggaagcuga     1320

gggacguacu ccagcagcgg cugaucaagu ucuuuauuga ucaaagcaaa aaggacgccg     1380

aaaaauaugc aaaguucuuu gaggauuacg guuuguucau gcgcgaaggc aucgugacug     1440

ccacggagca ggaggucaaa gaagacauug cgaagcugcu cagguaugag uccagcgccc     1500

ugcccagugg gcagcugacc uccuugagcg aauacgcauc ccggaugcgc gccggcacua     1560

ggaacaucua uuaccugugc gccccaaauc ggcaucucgc agagcacagu cccuacuaug     1620

aggcgaugaa gaaaaaggau accgaagugc uguuuuguuu cgagcaguuu gacgaacuca     1680

cccuguugca ucugcgcgag uucgauaaaa agaaacucau cagcgucgaa acugacauug     1740

ugguggacca cuacaaggag gagaaguuug aagauagguc cccagccgca gagugccuga     1800

gcgaaaaaga gacggaagaa cugauggccu ggaugcggaa cguauugggg aguaggguga     1860

ccaaugucaa ggugacucug cgccucgaca cccacccggc cauggucacc gugcuggaga     1920

ugggugcagc ccggcauuuc cucaggaugc aacagcuggc gaaaacucag gaggaacgcg     1980

cccaguugcu gcaacccacg cuggaaauca acccacggca cgcacucauu aagaaacuga     2040

aucaguugag ggccuccgag cccggccugg cccagcuccu gguggaucag aucuaugaaa     2100

acgcaaugau ugccgcgggg cucguagacg auccacgcgc cauggugggc cggcugaacg     2160

aguugcuggu caaggcacug gagaggcauu gaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  6939
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt7)

<400>  6939
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaagauca gcucccugcc cacccaacuc uucaaaugcu      120

guuuuugcga cuuccugaag gugaaaaugc acacuaugag uagcucccau uuguuuuacc      180

uggcccucug ucuguugacc uucacgagua gcgcaacugc cgggccagag acccugugcg      240

gugcggaacu cgucgaugcc cugcaguuug uguguggcga caggggguuc uauuuuaaca      300

agccgaccgg cuacgguucc agcucccggc gcgcacccca gacugggauu guagaugagu      360

gcuguuucag gaguugcgac cugcggcgcc ucgaaaugua uugugcccca cugaaacccg      420

caaagagcgc cagguccgug cgggcgcagc gccacaccga uaugccaaag acgcagaaag      480

agguccauuu gaagaaugcc agcaggggca gugcaggcaa caaaaauuac cggaugugag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  6940
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt7)

<400>  6940
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca uggguaagag caugcuggug cuccugaccu      120

ucuuggccuu ugcauccugc uguauugccg cguacaggcc aagugagacu cugugcgggg      180

gcgaacucgu cgacacccug caguucgugu guggggaucg gggcuuuuau uucagccgcc      240

cggccuccag gguaagucgg cgcagcaggg guaucgugga ggaaugcugu uuucgguccu      300

gcgacuuggc acugcucgag acguacugug ccacucccgc aaaaagcgaa cgcgaugucu      360

ccaccccacc caccgugcug ccagacaacu uccccaggua uccagugggg aaguuuuucc      420

aauacgauac uuggaaacag aguacccagc ggcugcgcag gggccucccg gcccuguugc      480

gggcgcgcag gggccacguc cuggccaagg agcucgaggc auuucgggaa gccaaacgcc      540

auaggccccu gauugcccug ccaacgcagg accccgcaca cgggggugcc ccacccgaga      600

uggcgagcaa ucggaaguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  6941
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt7)

<400>  6941
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagcuucu ccaccagugc cuuuggcccc guggcauuca      120

gccuggggcu ccuguugguc cugccagccg cguuuccggc ccccgugcca cccggugagg      180

acuccaagga uguagcagcc ccacacaggc agccccucac caguagcgaa cggaucgaca      240

aacaaauucg cuacauccug gauggcauuu ccgcauugag gaaggagacu ugcaauaaaa      300

gcaacaugug ugaauccagu aaggaggccc uggcggaaaa uaaccucaau cugccaaaaa      360

uggccgagaa ggacgggugc uuccagagcg gcuuuaacga ggaaacgugu cuggugaaga      420

ucauuacugg ucuccuggag uucgaagucu auuuggagua ccugcagaau cgguuugagu      480

ccagcgaaga acaggcacgc gccgugcaaa ugaguaccaa agugcucauc caguuccugc      540

agaagaaagc caagaaccug gaugcaauca ccacuccgga ccccaccacg aaugccuccu      600

ugcucacuaa acugcaggcg caaaaccagu ggcugcagga uaugaccacu caucucauuc      660

ugaggagcuu uaaggaguuc uugcagucca gucugcgggc ccuccgccaa augugaggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  6942
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt7)

<400>  6942
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccugcucu ggcugagggg cuucuugcug gccagcugcu      120

ggaucauugu gcgguccagu ccaaccccgg ggagcgaggg ucacuccgca gcccccgacu      180

guccaaguug cgcgcucgcc gcacugccca aggauguccc aaacagccag cccgaaaugg      240

uggaggccgu gaaaaagcau aucuugaaua ugcugcaccu caaaaagcgc ccagacguaa      300

cucaaccggu ccccaaagca gcccugcuga acgcgauuag gaagcuccau gugggcaagg      360

ugggggaaaa uggcuacguc gagaucgaag augacauugg ucggcgcgcc gagaugaacg      420

agcugaugga acagaccucc gagaucauca cguuugcaga aagcgggacu gccaggaaaa      480

ccuugcacuu cgagauuucc aaggagggca gugaucugag cgugguagaa cgggccgagg      540

uguggcucuu ucugaaaguc ccaaaggcaa aucgcaccag gacuaaagug accauccggc      600

uguuccagca gcaaaagcau ccccagggcu ccuuggacac gggggaagag gccgaagagg      660

ugggucucaa aggcgagcgc agcgaacugc ugcucaguga gaaggucgug gaugcgagga      720

aguccacuug gcacguauuu ccagugagcu ccaguauuca gcggcuguug gaccagggga      780

aaagcucccu ggauguccgc aucgccugug aacaaugcca ggagagcggc gcaagucucg      840

ugcugcuggg uaagaaaaag aaaaaggaag aggaggggga aggcaagaaa aagggcgggg      900

gugagggcgg ggccggcgca gacgaagaga aagaacaguc ccacaggccc uucuugaugc      960

uccaggcccg gcaaagcgag gaucauccgc accgcaggcg gcgcaggggu cuggagugug     1020

acggcaaggu gaacauuugc uguaaaaagc aguuuuucgu caguuuuaag gauaucgggu     1080

ggaaugacug gauuaucgcc cccuccggcu aucaugcgaa cuacugcgaa ggggaguguc     1140

caagccacau cgcagguacc agcggcucca gucugagcuu ccacuccacu gugauuaauc     1200

auuaucggau gagggggcac agccccuuug ccaaccucaa aaguugcugc guaccaacca     1260

agcugcgccc cauguccaug uuguacuaug acgauggcca gaauaucauu aaaaaggaca     1320

uccaaaacau gauuguggaa gagugugguu gcagcugagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  6943
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt7)

<400>  6943
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccugc ccgggagggc ccucggugca gccugccugu      120

ugcugcucgc ggccggcugg cuggggccag aggcaugggg cagcccgacu cccccaccca      180

ccccagccgc acccccaccg cccccacccc cagguucccc cgggggcagu caggauaccu      240

guacgagcug cggcggguuc cggcgcccgg aagaguuggg uaggguggac ggcgauuuuc      300

uggaagccgu caagcggcac auccucuccc gccugcaaau gagggggcgg cccaacauua      360

cucaugcggu gccaaaagcc gcaaugguaa ccgcccugcg caagcuccac gccggcaaag      420

ugagggagga cggucggguc gaaauccccc aucuggaugg gcacgcaagu ccaggcgccg      480

acggccagga gcgcgugagc gagauuaucu ccuucgcgga aaccgauggg uuggccagcu      540

ccagggugcg gcuguacuuu uucauuagua augaggguaa ccagaaucuc uuugucgugc      600

aggcaagccu guggcuguau uugaagcucc ugcccuacgu acuggaaaaa ggcucccgca      660

ggaaggugcg ggucaaggug uauuuccaag agcaggggca uggcgaccgc uggaacaugg      720

uggagaaaag ggucgaucuc aagcggagcg guuggcacac uuuuccacug accgaagcca      780

uccaggcauu guucgagcgc ggcgaaaggc ggcugaaucu cgacgugcag ugugauaguu      840

gccaagagcu ggccguagug ccggucuuug uggaccccgg ggaagagucc cacaggccau      900

ucguggucgu gcaggcccgc cugggcgaua gccggcauag gauccgcaaa cggggguugg      960

agugugacgg uaggacgaac cucugcuguc gccagcaguu uuucauugac uuccggcuga     1020

ucggcuggaa ugauuggauu aucgcgccca cuggguacua uggcaacuac ugcgaagguu     1080

ccuguccagc auaucuggcc ggcguacccg ggagugccag cuccuuucac accgcagugg     1140

ucaaucaaua caggaugcgg ggccucaacc cggggacugu gaauagcugc ugcauuccaa     1200

ccaagcugag uaccaugucc auguuguacu ucgacgauga guauaacauc gucaaacgcg     1260

acgugcccaa uaugauugug gaagagugug gcugcgccug aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  6944
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt7)

<400>  6944
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccugaggg ugcuccuguu gaccgcacug acucucugcc      120

acggcuucaa ccuggacacc gagaaugcca ugacguuuca ggaaaacgcg cggggguucg      180

gucaaagcgu cgugcaguug cagggcuccc gcguaguggu cggggcgccc caggagaucg      240

uggcagccaa ucaaaggggc agucuguacc agugugauua uagcacuggu uccugcgaac      300

caauucggcu ccaggugccg gucgaggcag ugaacaugag ucuggggcug agccucgccg      360

cgaccaccuc cccaccccag cuguuggccu guggccccac uguacaucaa accugcagcg      420

aaaauacgua cgugaagggc cuguguuuuc ucuucggguc caaccugcgc cagcagccac      480

agaaauuucc cgaggcacug agggguugcc cacaagagga cagugauauc gccuucuuga      540

uugacggcag cggguccauc auuccgcacg auuuucggcg caugaaggag uucgucagca      600

cugugaugga acagcucaaa aagaguaaaa cccuguuuuc ccugaugcag uauagcgaag      660

aguucaggau ccauuuuacu uucaaggagu uccaaaauaa ccccaaucca cggucccucg      720

ugaagcccau cacccagcug uugggccgca cccacacggc cacugguauu aggaaagucg      780

ugcgggaacu guuuaacauc accaaugggg cacgcaagaa cgccuucaaa auucucguag      840

ugaucacuga cggcgagaag uuuggcgauc cacuggggua cgaagacguc auucccgagg      900

cggauaggga aggugugauc cgguauguga uuggcgucgg ggacgccuuc cgcagugaga      960

aaagcaggca ggagcugaau accaucgcau ccaagccgcc ccgggaucau guguuucagg     1020

uaaacaauuu cgaagccuug aaaaccaucc aaaaccagcu ccgcgagaag auuuuugcaa     1080

ucgaaggcac ucagacgggu agcaguucca gcuucgagca cgaaaugagu caggagggcu     1140

uuuccgccgc cauuaccagc aacgggccac ugcugagcac ugugggcucc uacgacuggg     1200

ccgggggugu cuuccucuau accaguaagg agaaaagcac cuuuaucaau augacuaggg     1260

uggauuccga caugaacgac gcauaccugg gcuacgccgc cgcaauuauc uugcggaaua     1320

ggguccaaag ccuggugcuc ggggcgcccc gcuaucagca caucggccug guggccaugu     1380

uccggcagaa cacggguaug ugggaaagua augccaacgu aaagggcacc cagauugggg     1440

cauacuuugg cgccucccug uguagcgugg augucgacuc caaugggagu acugauuugg     1500

ugcucaucgg cgcaccacau uauuacgagc aaaccagggg ugggcagguc agcgugugcc     1560

cccugccacg cggccgggcc agguggcagu gugacgccgu gcuguauggu gaacagggcc     1620

aaccgugggg gcgcuucggc gcagcccuca ccguacuggg ggaugugaac ggcgacaaau     1680

ugacugaugu cgcgauuggu gcccccgggg aggaagacaa ucggggcgca guguaccugu     1740

uccacggcac guccgggagc gguaucaguc caucccauag ccagaggauu gccggcucca     1800

agcucagucc ccggcugcag uauuuugggc aaagccuguc cggcggucag gauuugacca     1860

uggacgggcu ggucgaucuc acugugggcg cccagggcca cgugcugcuc cugcgcagcc     1920

agccaguauu gagggucaaa gcaaucaugg aguucaaccc ccgggaggug gcgcgcaaug     1980

uguuugaaug caacgaccaa gucgugaagg ggaaggaggc cggugaagug aggguaugcc     2040

ugcacgucca gaaaaguacc cgggaccgcc ucagggaggg ccagauccag uccgugguga     2100

cuuacgaucu ggcacuggac agcgggcggc cgcauuccag ggccgucuuc aaugagacca     2160

agaacagcac gcgccggcaa acccaggugu ugggccugac ucagaccugu gaaacucuca     2220

aacugcagcu cccaaauugc auugaggauc ccguaagucc caucgugcug agguugaacu     2280

uuagccuggu cgguacccca cuguccgccu ucgggaaccu ccgccccgug cuggcagaag     2340

acgcccaacg guuguuuacg gcgcuguucc cauuugagaa gaauuguggc aacgauaaua     2400

uuugccagga cgaucucagu aucaccuuca gcuuuauguc ccuggacugu cucguggucg     2460

gcgggccgag ggaguucaac gugacuguaa ccgugcgcaa ugauggugaa gacagcuacc     2520

ggacucaggu caccuucuuu uucccccugg auuuguccua uaggaaagug aguacgcugc     2580

aaaaccagcg cagccagcgg uccuggaggc uggccugcga gagugcaagc uccaccgaag     2640

ugagcggcgc ccucaagagu acuuccugua gcauuaauca cccaaucuuu cccgagaacu     2700

ccgaagucac cuucaauauu acuuuugacg uggauagcaa ggccagucug gggaacaaau     2760

ugcugcucaa ggcaaaugua accuccgaga acaauaugcc acgcacgaac aaaaccgagu     2820

uccagcugga acugcccgug aaguacgccg ucuauauggu ggugacuagc cauggcguca     2880

guaccaaaua ccucaauuuu acugcguccg agaacaccag ccgggugaug caacaccagu     2940

aucagguauc caaccugggu cagaggagcu ugccgaucag ucugguguuc cucgucccag     3000

ugcgccugaa ucaaacugug aucugggacc ggccccaggu caccuuuagc gaaaacuugu     3060

ccaguacgug ccauaccaag gagaggcugc caagccacuc cgacuuccuc gccgaacugc     3120

gcaaggcacc cgugguaaau uguagcauug ccgugugcca gaggauccag ugcgauauuc     3180

cguuuuucgg gauccaagag gaauuuaacg caacucugaa aggcaaucuc uccuucgacu     3240

gguacauuaa gaccagucac aaccaucugu ugaucgucag cacugccgag auccuguuca     3300

augauuccgu guuuacccuc cugcccggcc agggggcguu cgugcggagc cagacggaga     3360

ccaaagucga accauuugag gugcccaacc cauugccccu gauuguaggu aguuccgugg     3420

gcgggcuccu gcugcucgcc cugaucacug cagccuugua uaagcugggc uucuuuaaaa     3480

ggcaguacaa ggacaugaug agcgaaggug gcccaccggg ggccgagccc caaugaggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  6945
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt7)

<400>  6945
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucagccuga agacccuccc cuuucuguug cugcuccacg      120

ugcagaucuc caaagccuuc ccagucagua gcaaggagaa aaacacuaag accgugcaag      180

acuaccugga aaaauuuuau caguugccgu ccaaucagua ccagaguacg aggaagaacg      240

gcacuaaugu aauuguggag aagcugaaag aaaugcaacg guucuuuggg cucaacguca      300

ccgguaagcc caaugaggaa acccuggaua ugaugaaaaa gccacgcugc ggcgugcccg      360

acagcggggg cuucaugcug acuccaggua accccaaaug ggagaggacc aaucucacgu      420

aucggauccg caacuacacu ccacagcugu ccgaggcaga aguggagagg gccauuaagg      480

augcguuuga auuguggagc gucgccuccc cgcugaucuu cacccggauu agucaggggg      540

aggcagacau caauaucgcc uuuuaucagc gcgaucaugg cgacaacagc cccuucgaug      600

gcccaaaugg gauucucgca cacgccuuuc aacccgguca gggcaucggg ggcgacgcgc      660

auuucgaugc cgaggaaacu uggaccaaca ccuccgcaaa uuacaaccug uuccuggugg      720

ccgcccacga guuuggucau agcuuggggc ucgcacacag uuccgaccca ggcgcccuga      780

uguaucccaa uuacgcguuc agggaaacga gcaacuacuc ccugccgcag gaugacauug      840

auggcaucca ggccauuuau gggcucagua gcaaccccau ccaaccaacu ggucccucca      900

ccccaaaacc cugugaccca agccugacuu uugacgcaau uaccaccuug cggggcgaga      960

uccuguucuu uaaggaucgc uacuucugga ggcggcaccc gcagcuccag cgcguagaaa     1020

ugaauuuuau cagucuguuc uggcccuccc ugccaacugg gauucaagcc gcauaugagg     1080

acuuugauag ggacuugauc uuccucuuua agggcaacca guacugggcc cugagcgguu     1140

augauauucu gcagggcuac cccaaagaca ucaguaauua uggguuccca uccagcgugc     1200

aggccauuga ugcggcaguc uuuuaccgga gcaagacgua cuucuucgug aacgaccaau     1260

uuuggcgcua ugauaaucag aggcaguuca uggagcccgg cuacccgaaa uccaucagug     1320

gggccuuucc agguaucgaa agcaaggugg acgccgucuu ccagcaagag cacuuuuucc     1380

auguguuuuc cggcccccgg uauuacgcau ucgaucucau ugcccagcgc guaaccaggg     1440

uggcgcgggg gaacaaaugg cugaauugca gguauggcug aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  6946
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt7)

<400>  6946
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguggc agccccucgu gcuggucuug cuggugcucg      120

gcugcuguuu cgccgcacca aggcaacggc aguccacccu gguauuguuu ccgggggacc      180

ugcgcacuaa ccucaccgau aggcagcugg ccgaggaaua ccuguaucgg uacgguuaua      240

cgcgcguggc ggagaugagg ggcgaaagua agagccucgg gcccgcccug uugcugcucc      300

agaaacaacu gucccugcca gagacuggcg aauuggacag ugcaacccuc aaggccaugc      360

ggacccccag gugcgguguc ccagaucugg ggagguucca gacuuuugag ggcgaccuga      420

aauggcacca ucacaauauc accuacugga uucagaacua uagcgaggau cucccccggg      480

cagugaucga cgaugccuuc gcgcgcgccu uugcacugug guccgccgug acgccauuga      540

cuuucaccag ggucuacagc cgggacgccg auauugugau ccaguuuggc guagcagaac      600

auggggacgg uuauccguuc gauggcaagg acgggcugcu cgcccacgcg uuucccccag      660

gccccgguau ucaaggggau gcccauuucg acgacgauga gcuguggucc cugggcaaag      720

gcguggucgu gccaacucgc uuugggaaug cagacggugc cgcaugucac uuccccuuca      780

ucuuugaagg caggaguuac agcgccugca ccaccgaugg gcgguccgac ggcuugccgu      840

gguguagcac gacugccaac uacgauaccg acgaucgcuu cgguuuuugc cccagugaga      900

ggcucuauac ucaggacggc aaugcggaug ggaagccaug ucaguucccc uuuaucuucc      960

agggccaauc cuacagcgca ugcaccaccg acgggcgguc cgaugguuau cgcuggugug     1020

ccacuacggc caacuacgac agggacaagc uguuuggcuu cugcccaacc cgggcagaua     1080

guacugugau gggcgggaau agcgccggug agcugugcgu cuuucccuuc accuuucucg     1140

gcaaagaaua uuccaccugu acuagcgagg ggaggggcga cgggcgccug uggugcgcga     1200

cgaccaguaa cuucgauucc gacaagaaau ggggcuuuug uccagaucag gguuacagcu     1260

uguuccuggu ggccgcacac gaguucgggc augcccucgg ccuggaccac aguuccguac     1320

cggaagcacu gauguauccc auguaccggu uuacugaagg uccacccuug cauaaggaug     1380

acgugaaugg cauuaggcac cucuacgggc cacgccccga gccggagcca cggccaccca     1440

ccaccacuac gccccagccc accgccccac cgacugucug ccccaccggc ccacccacug     1500

ugcacccaag cgaaaggccc accgccgggc cgacgggccc acccagcgca gguccaaccg     1560

ggcccccgac ugccggcccc uccaccgcga cuaccgugcc acugaguccc gucgaugacg     1620

ccuguaacgu gaauaucuuc gaugcaauug ccgagaucgg caaccaacug uaucucuuua     1680

aagacgggaa guacuggcgc uucagcgaag gucggggcuc caggccacag gggcccuuuc     1740

ugauugccga uaaauggcca gcauugccgc ggaagcugga cagcguauuc gaggaacgcc     1800

ucaguaagaa acuguuuuuc uuuuccggcc gccaggugug ggucuauacg ggugcgagcg     1860

ugcuggggcc ccggcgcuug gacaagcugg gccucggcgc cgaugucgca caggugaccg     1920

gggcccugag guccggucgg ggcaaaaugc uccuguucag ugggcgcagg uuguggcggu     1980

uugacgugaa ggcccaaaug guagauccaa ggagcgcauc cgagguggac cgcauguucc     2040

ccggcguccc acuggauacu caugacgugu uccaguaccg ggagaaagcc uauuuuugcc     2100

aggauagguu cuacuggcgc gucagcaguc gguccgaacu caaucaggug gaccaagugg     2160

guuauguaac cuacgauauc cugcaguguc ccgaggacug aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  6947
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt7)

<400>  6947
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg ugcuggccgc auuccucuuu cugagcugga      120

cccauugcag ggccuugcca cugccguccg ggggugacga ggaugaccuc agugaagagg      180

aucugcaguu cgcggaacgg uacuugcgca gcuauuacca ccccacuaac cuggccggca      240

uccucaagga gaaugcagcc uccaguauga ccgaaaggcu gcgggagaug cagagcuuuu      300

ucgggcugga ggucacgggc aaacucgacg auaacacucu ggacgugaug aagaaaccac      360

gcuguggugu acccgaugug ggggaauaua augucuuucc aaggaccuug aaguggucca      420

aaaugaaccu gaccuaccgg auugugaauu auacucccga caugacccau agcgaggugg      480

aaaaggcauu caagaaagcc uuuaaggucu gguccgaugu gacgccacuc aacuucacuc      540

gccugcacga cggcaucgcg gauauuauga ucaguuuugg cauuaaagag cauggggacu      600

ucuacccguu ugaugguccc agcggccugu uggcccacgc auucccaccc gggccaaauu      660

auggcgguga cgcccacuuc gacgaugacg agaccuggac uuccagcagu aagggguaca      720

accucuuucu gguagccgca caugaguucg gccacucccu gggccucgau cauagcaaag      780

accccggggc ccugauguuu ccgaucuaca ccuauaccgg uaagucccac uucauguugc      840

ccgaugacga ugugcaaggc auccagaguc uguacgggcc aggcgacgag gaucccaauc      900

caaaacaccc caagacgcca gacaagugcg auccgagccu cucccuggac gcgauuacua      960

gccugagggg ugaaaccaug aucuuuaaag accgguucuu uuggcgcuug cauccccagc     1020

aagucgaugc cgaacucuuc cugacuaaga guuuuuggcc agaacugccc aacaggauug     1080

acgcagccua ugagcaccca ucccaugauc ucaucuucau uuuucggggc cgcaaauucu     1140

gggcacugaa uggguacgac aucuuggagg gcuaucccaa gaaaauuagc gaacuggggc     1200

ucccgaagga ggugaagaaa aucagugccg ccgugcacuu ugaagauacc gguaagaccc     1260

ugcuguucuc cggcaaccag gucuggaggu acgacgauac uaaucauauc auggacaaag     1320

auuauccacg guugauugag gaagacuucc ccgggaucgg cgauaaggug gacgcgguau     1380

acgagaaaaa cgguuacauu uacuuuuuca auggccccau ccaguuugag uauagcauuu     1440

ggagcaaccg caucgugagg gucaugccag caaacuccau ccucuggugu ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  6948
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt7)

<400>  6948
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acacuaccga agacuacgau acgacuaccg      120

aguucgacua uggcgaugcc accccaugcc agaaggugaa ugaaagggca uuuggggccc      180

aacugcuccc gccccuguac agcuuggucu ucgugaucgg ucugguaggc aacauucucg      240

ugguccuggu guuggugcag uauaaacggc ugaagaauau gacuuccauc uaccuccuga      300

accuggcgau uagugaccuc cuguuuuugu ucacccugcc auuuuggauc gauuauaaac      360

ucaaggacga uugggucuuc ggggacgcca uguguaaaau ucugagcggc uuuuacuaua      420

cgggucugua cuccgagauc uucuuuauca uuuugcucac uaucgaucgc uaccuggcaa      480

uugugcacgc cguauucgca cugagggccc ggaccgugac uuuugggguc aucaccagua      540

uuaucauuug ggcgcucgcc auccuggcaa gcaugcccgg cuuguauuuc uccaagaccc      600

agugggaauu uacgcaucac acuugcagcc ugcauuuucc acacgagucc cuccgcgagu      660

ggaagcuguu ccaggcccug aaauugaauc ucuuuggccu ggugcugccc cuccugguga      720

ugaucauuug uuacaccggg aucauuaaga ucuugcugag gcggccaaac gagaaaaaga      780

guaaagccgu ccgccucauu uucgugauca ugaucauuuu cuuccuguuu uggacuccgu      840

auaaucugac caucuugauu agcguauucc aagacuuucu cuucacccau gaaugcgaac      900

aguccaggca ccuggaucug gcagugcagg ucacugaggu gaucgccuac acgcacuguu      960

gcgugaaccc cgucauuuau gcguuugugg gugagcgguu ccgcaaguac cucaggcagc     1020

uguuucaucg gcgcguagcc gugcacuugg ucaaauggcu gccauuccuc agcguggaca     1080

ggcuggaacg ggucaguucc accagccccu ccacuggcga gcaugaacug agugcagggu     1140

ucugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  6949
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt7)

<400>  6949
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aggacccugg ccugccuccu guugcugggc uguggguacc      120

ucgcacacgu gcuggccgag gaagcggaga ucccccggga agucauugag cgcuuggcca      180

ggagccagau ccauuccauu cgggaccugc aacgccuccu ggaaaucgau agugugggua      240

gcgaggacuc ccuggauacc agucucaggg cacacggcgu acaugccacu aagcacgugc      300

cagagaaacg gccgcugccc auucgcagga agcggagcau cgaagaggca gucccagccg      360

ugugcaaaac gcgcacugug aucuaugaaa uucccagguc ccaggucgac ccaaccagcg      420

cgaacuucuu gaucuggccc ccaugugugg agguaaagcg gugcaccggg uguugcaaua      480

cuuccagugu gaaaugucag ccgagccgcg uccaucacag guccgugaag guggccaagg      540

ucgaguacgu gcggaaaaag cccaaacuga aggaaguaca ggugcgccuc gaggaacacc      600

uggagugcgc augugccacc acgagccuga acccagauua uagggaagag gacacuggcc      660

ggccccgcga gagugguaaa aagaggaaac ggaagagguu gaagccaacc ugaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  6950
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt7)

<400>  6950
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacaggugcu gggcccuguu ccucagccug uguugcuacu      120

ugcggcuggu guccgcagag ggcgacccca ucccagagga acucuaugaa augcugagug      180

aucacagcau ucgcuccuuu gacgauuugc agaggcugcu ccauggggac ccgggugagg      240

aagauggcgc cgagcuggac cugaauauga cccggaguca cagcgggggc gagcucgaau      300

cccuggcgcg cgguaggcgg agcuuggggu cccugacuau cgccgagccc gcaaugauug      360

ccgaauguaa gacccgcacg gaggucuucg agaucaguag gcggcucauu gaucgcacua      420

acgcaaauuu ucuggugugg ccacccugcg uagaagugca aagguguagc ggcugcugua      480

acaaucggaa cguccagugc cgcccaaccc aggugcagcu gaggcccgug caaguccgga      540

aaaucgagau cgugcgcaag aaaccaauuu ucaagaaagc caccguaacu uuggaagacc      600

aucucgcgug uaagugcgag accguggccg cagccaggcc ggucacgcgg ucccccggcg      660

ggagccagga acagcgcgcc aagacuccac agaccagggu gacuauccgg accgugaggg      720

uccgccggcc cccaaaaggu aagcacagga aauuuaagca uacccacgau aaaacggcac      780

ugaaggagac ucugggcgcc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  6951
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt7)

<400>  6951
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguucg gccuccuguu gcugaccucc gcccucgcag      120

ggcagaggca agguacucag gccgagagua accugagcuc caaguuucag uucaguagca      180

auaaagaaca gaacggcgug caagaccccc agcacgagcg gaucauuacc gucuccacga      240

augggagcau ccauucccca cgcuuuccgc acacuuaccc caggaacacc guguugguau      300

ggcggcuggu ggcggucgaa gagaaugugu ggauucagcu caccuucgau gaacgcuuug      360

gccuggagga cccagaggau gacaucugca aguaugauuu cguggaaguc gaggaaccca      420

gugacgguac uauucugggg agguggugug gcagcggcac cgugccaggg aaacagaucu      480

ccaaggguaa ccaaauccgg auucgcuuug uaagcgauga guacuucccc agugagccag      540

gcuuuugcau ccauuauaau auugugaugc cgcaguucac ggaagccguc ucccccagcg      600

ugcucccacc cuccgcacug ccauuggacc ugcucaacaa ugccaucacu gcauuuagua      660

cccuggagga ucugauuagg uacuuggaac ccgagcggug gcagcucgac cuggaagauc      720

uguaucgccc gacuuggcag cuccugggga aagccuucgu guucggcagg aaaagccggg      780

ucguggacuu gaaccugcuc accgaggagg uacgccugua cuccuguacc cccaggaauu      840

uuagcgugag uauccgggag gaacugaagc gcacggauac uauuuucugg ccagguugcu      900

ugcucgucaa gagguguggg ggcaacugcg cguguugccu gcacaauugu aacgaaugcc      960

aaugcgugcc cuccaaggug accaaaaagu aucaugaggu ccugcagcuc cggccaaaaa     1020

cuggcgugcg cgggcugcac aagagcuuga ccgacguagc ccuggaacac caugaggagu     1080

gugacugcgu guguaggggu aguaccggcg ggugaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  6952
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt7)

<400>  6952
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaggcuga ucuucgugua cacccucauu ugcgccaacu      120

uuuguagcug ccgggacacu uccgcaacgc cccagagugc cagcaucaag gcgcugcgca      180

augccaacuu gaggcgggau gaccuguauc gcagggauga gaccauucaa gucaaaggca      240

auggguacgu gcagucccca cgguucccga acaguuaucc ccgcaaucuc cuguugacuu      300

ggaggcugca uagccaggaa aacacccgga uccagcucgu auuugacaau caauucgguc      360

uggaggaagc agagaacgau auuugucgcu acgacuuugu ggaagucgag gauaucuccg      420

agaccagcac uaucauuagg ggccgguggu gcgggcacaa ggaagugcca ccccgcauca      480

aauccaggac caaucagauu aagaucacgu ucaaaaguga cgauuauuuu guggccaagc      540

caggcuucaa gauuuacuau agccugcucg aggacuuuca gcccgcagcc gcguccgaaa      600

cuaacuggga gagcgucacc aguuccauca gcgguguguc cuacaauagu ccaagcguaa      660

cugauccgac ccugauugcc gacgcauugg auaaaaagau cgccgaguuc gacaccgugg      720

aagaccugcu caaauacuuu aaccccgagu ccuggcagga agaucuggag aauauguauc      780

uggacacgcc acgguaccgc gggaggagcu aucaugaucg gaagaguaaa gucgacuugg      840

aucgccucaa cgacgaugcc aagagguacu ccuguacucc ccggaauuau agcgugaaca      900

ucagggagga acugaaacug gcaaacgugg ucuucuuccc acgcugccuc cuggugcaac      960

gguguggcgg caauugcggg ugugguaccg uaaacuggag gaguugcacu ugcaauuccg     1020

gcaagaccgu gaagaaauac cacgaggucu ugcaguuuga acccgggcau auuaagcgcc     1080

ggggcagggc caaaaccaug gcgcuggugg acauccagcu cgaucaccac gagcgcugug     1140

acugcauuug uagcagccgg ccgcccaggu gaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  6953
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt7)

<400>  6953
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugacccaca gcaaguuccc cgccgcaggc auguccaggc      120

cacuggacac cagucuccgg cugaaaacuu uuagcuccaa gagugaguac caguuggucg      180

ugaacgccgu acgcaaacug caagaaagcg gguucuauug guccgcggug acggguggcg      240

aggccaaucu ccuguugagc gcagaaccgg ccgggacuuu ucugaucagg gauuccagug      300

accagcggca uuucuuuacc cucagcguca agacccaguc cggcacuaaa aaccugcgca      360

uucagugcga gggugggagc uucagucugc aauccgaucc caggagcacc cagccagugc      420

cccgguuuga cugugugcuc aagcuggucc accauuacau gccaccccca ggcgcaccgu      480

ccuuccccag uccacccacg gaaccaagcu ccgaggugcc cgagcagccg agcgcccagc      540

ccuugccagg caguccccca cgcagggcgu auuacaucua uuccgggggu gaaaagauuc      600

cccugguacu cagccggcca cugaguucca auguggccac ucugcaacac uugugccgca      660

aaaccgucaa cggccaucuc gauagcuacg agaaggugac ucagcugccg gggcccauca      720

gggaauuucu ggaccaguau gaugcaccac ucugaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  6954
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt7)

<400>  6954
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gugcccagcg ccggccagcu ggcacucuuc gcccugggga      120

ucgucuuggc ggccugccaa gcacuggaga acuccaccag uccacucagc gccgacccgc      180

ccguggcagc cgcgguagug ucccacuuua augauugucc agacagucau acucaguucu      240

gcuuucacgg uaccuguagg uuccuggucc aggaagauaa gcccgccugc gugugucaua      300

gcggcuacgu gggggcacgg ugcgagcacg ccgacuugcu ggccgucgug gcagccuccc      360

agaaaaagca agcgauuacg gcccucguag uggucagcau cguggcacug gccgugcuga      420

uuaucacuug uguccucauu cauugcuguc aggugcgcaa acacugcgaa uggugcaggg      480

cacugaucug ucggcacgag aagccauccg ccuugcugaa aggccgcacc gccugcuguc      540

auagugaaac cguaguguga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  6955
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt7)

<400>  6955
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccccaagcg gccugaggcu ccugccguug cugcuccccc      120

uguuguggcu gcucgugcug accccagggc ggcccgccgc aggucugucc acuugcaaga      180

ccaucgacau ggagcucguc aaacgcaaga ggauugaagc cauccggggc cagauucuga      240

guaaauugcg ccuggcgagc ccacccuccc aaggggaggu gccaccgggc ccccucccag      300

aagccguacu ggcacuguac aacaguacga gggaucgggu ggccggugag agcgcagaac      360

ccgagccaga gcccgaagcc gacuauuacg cgaaggaggu cacucgcgug uugauggugg      420

aaacccacaa ugagaucuau gauaaauuca agcaguccac ccauagcauu uacauguuuu      480

ucaacacuuc cgagcucagg gaagccgucc cggagcccgu gcugcugagu cgggcagaac      540

uccgccuguu gaggcugaag cucaaaguag agcagcacgu ggaacuguau cagaaguaca      600

gcaauaacuc cuggcgguau cugagcaauc gcuugcucgc cccaagugac ucccccgagu      660

ggcugagcuu ugaugucacc ggggugguga ggcaauggcu gucccggggc ggcgagaucg      720

aaggguuccg ccucagugcc cauuguagcu gcgacuccag ggauaacacg cugcaggucg      780

acaucaaugg uuuuacuacc ggccggcgcg gggauuuggc aacuauucac ggcaugaaca      840

ggccauuccu gcuccugaug gccacgcccc uggagcgggc gcagcauuug cagagcagua      900

ggcaccgccg ggcccucgac accaauuacu guuuuuccag caccgagaaa aacugcugug      960

ugaggcaacu guacaucgau uuccgcaagg accuggguug gaaauggauu cacgaaccaa     1020

agggguauca ugcaaauuuu ugccucggcc cgugucccua caucuggagu cuggauacuc     1080

aguauuccaa aguauuggcc cuguacaacc agcacaaucc aggcgcaagc gccgcccccu     1140

gcugugugcc acaggcgcuc gaaccccugc cgauugucua uuacgugggg cggaagccaa     1200

agguggagca acugagcaac augaucguca gguccugcaa augcaguuga ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  6956
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt7)

<400>  6956
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg ugcugagcgc cuuccucauc cugcauuugg      120

ucaccguggc acugucccuc aguacuugua gcacccugga cauggaucag uuuaugagga      180

agcggauuga ggccauccgc ggccaaauuu uguccaaacu gaagcucacg agucccccag      240

aagacuaucc ggagcccgaa gagguaccac ccgaagugau cagcauuuac aacuccacua      300

gggaucugcu gcaggagaaa gcgagccggc gcgccgcagc cugcgagagg gaacgguccg      360

acgaggaaua uuacgcaaag gaggucuaua aaaucgauau gccacccuuc uuuccaagug      420

agaaugccau cccgcccacc uucuaccgcc cauauuuuag gauugugcgg uucgacguga      480

gcgcgaugga aaagaacgcc uccaaucucg ucaaggcaga guuucgcgug uucaggcugc      540

agaaccccaa agcccgggua ccagaacagc gcaucgaguu guaccaaauu cucaagagca      600

aagaucugac cagucccacu cagagguaca ucgacuccaa gguggucaaa acccgggccg      660

aaggggagug gcugagcuuu gaugugacgg acgcagugca cgaguggcug caucacaagg      720

aucgcaauuu ggguuucaaa auuucccucc auuguccgug cuguacuuuu guccccagua      780

acaauuauau cauuccaaac aagagcgagg aacuggaagc cagguucgcg ggcaucgacg      840

ggaccuccac uuacaccagc ggcgaucaga agaccaucaa aaguacgcgg aagaaaaauu      900

ccgguaagac uccccaucug cuccugaugu ugcugccaag cuaucgccuc gagagucagc      960

aaaccaacag gcggaaaaag agggcccugg acgcagccua cugcuuccgc aaugugcagg     1020

acaacuguug ccugcggccc uuguauauug auuuuaagag ggaccucggg uggaaaugga     1080

uccacgaacc aaagggcuac aaugcaaacu ucugugccgg cgccugcccg uaucuguggu     1140

ccagcgauac ucagcacagc cgcguacugu cccucuacaa uaccauuaac cccgaggcga     1200

gugcaagccc augcugugug ucccaggacc uggagcccuu gaccauccug uacuauauug     1260

ggaaaacucc aaagaucgaa caacucagca acaugaucgu caaaaguugc aaguguuccu     1320

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  6957
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt7)

<400>  6957
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcauc ugcagagggc ccucgugguc cuggcauugc      120

ugaacuucgc caccgugagc cucucccuga guacuugcac cacguuggac uuuggccaca      180

ucaaaaagaa acggguagag gcgauucgcg ggcaaauccu gagcaagcuc aggcugacuu      240

ccccacccga accgaccgug augacccacg uccccuacca ggugcuggcc cucuauaaua      300

guacucggga gcuguuggaa gagaugcaug gugaacgcga ggagggcugu acccaggaaa      360

acacggagag cgaauacuau gcaaaagaga uucacaaguu cgauaugauc caggggcugg      420

ccgagcauaa ugaacucgca gugugcccaa agggcauuac uuccaaaguc uuuagguuca      480

acgugagcuc cguagagaag aaucggacca accuguuucg cgccgaguuc agggugcugc      540

ggguccccaa uccaaguagc aaacgcaacg aacaaaggau cgaauuguuu cagauccucc      600

ggcccgacga gcacauugcg aagcagcgcu acaucggugg gaaaaaucug ccaacuaggg      660

gcaccgccga guggcugucc uucgauguga ccgacacggu gcgggaaugg cuccugcgca      720

gggagagcaa cuugggccug gaaauuagua uccacugucc gugccauacu uuucagccca      780

auggggauau ucucgagaac auccacgaag ucauggagau uaaguucaaa gguguggaca      840

augaggauga ccauggccgc ggggaucugg gccggcugaa gaagcaaaaa gaccaccaca      900

acccacauuu gauccucaug augauucccc cacacaggcu ggauaauccc ggucaagggg      960

gccagcggaa gaaaagggca cuggacacca acuauuguuu ucgcaaccuc gaagagaauu     1020

gcuguguacg gccgcuguac aucgauuuca ggcaggacuu gggcuggaag ugggugcaug     1080

aacccaaagg guauuacgcc aacuucugcu ccgguccaug ucccuaccug cgcagcgccg     1140

acacuaccca cuccaccguc cucggccugu auaauacucu gaacccagag gcaagugcca     1200

gccccugcug cgugccacag gauuuggaac cgcucacgau ccuguacuau guggggcgga     1260

cccccaaggu cgagcagcug uccaauaugg ugguaaagag cuguaaaugc aguugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6958
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt7)

<400>  6958
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccccgugg cagucugggc cgcgcuggcc gugggccucg      120

agcugugggc agccgcacac gccuugccag cgcagguagc cuucaccccg uacgcacccg      180

aaccagggag cacuugcagg cugcgggagu auuacgacca aaccgcccag auguguugcu      240

ccaaguguag ucccggucag caugccaaag uguuuugcac gaagacuagc gauaccgucu      300

gugacuccug cgaagauagu accuauacuc agcucuggaa cugggugcca gagugucuga      360

gcugcggcuc ccgcuguagc uccgaccaag uggaaaccca ggcaugcacg agggagcaga      420

aucggaucug cacuugucgc cccggguggu acugcgccuu gaguaaacag gagggcugua      480

ggcugugcgc gccacuccgg aagugucgcc cggguuucgg ggucgccagg cccggcaccg      540

aaacuagcga ugugguaugc aaaccaugug cacccggcac cuuuuccaac accacgagca      600

guacugacau uugccggcca caccaaaucu guaauguggu cgccauuccc gggaacgcau      660

ccauggaugc cgugugcacc agcacuuccc cgacccgcag uauggccccc ggugcggugc      720

aucugccaca gcccgucagc accagguccc agcacacuca gccaacgccc gagccaagca      780

ccgcaccgag uacuuccuuc cugcucccca ugggcccaag ucccccagcc gaagggagca      840

ccggcgacuu ugcccugccc guggguuuga ucguaggggu gaccgcacug ggccuccuga      900

uuaucggcgu cgugaauugc gugaucauga cucaagucaa gaagaaaccg cuguguuugc      960

agcgggaggc caaggugcca caucuccccg cggauaaagc ccgcgggacg cagggucccg     1020

agcaacagca ucugcugauu accgcaccau ccagcagcuc caguagccuc gaauccagcg     1080

ccagugcacu ggacaggcgg gcccccacuc gcaaccagcc acaggccccg ggcguagagg     1140

cauccggggc cggcgaagcg agggccagca ccgguuccag ugauagcucc cccggcgggc     1200

acggcaccca agugaauguc acuugcaucg ugaacgucug uagcaguucc gaccacagcu     1260

cccagugcag uagccaggca uccagcacga ugggggauac cgacaguucc ccaagcgagu     1320

cccccaagga cgaacaggug ccauucagca aagaggagug ugccuuucgg agucaauugg     1380

aaacucccga gacccugcuc gguagcacug aagagaagcc gcugccacug ggcgugcccg     1440

augccgggau gaaaccaucc ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  6959
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt7)

<400>  6959
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgugauga ggcuguuccc augcuuucuc cagcuguugg      120

ccggccuggc acucccggcc gugcccccac aacagugggc gcugagcgcc gggaacgguu      180

ccagugaggu cgaaguagug cccuuccagg aggucugggg ccggagcuac ugucgcgcau      240

uggaaaggcu gguggacgug gucuccgagu auccaaguga aguggagcac auguuuagcc      300

ccuccugcgu aagccuccug cgguguaccg ggugcugugg cgaugagaau cugcauugcg      360

ugccagucga aacugccaac gugaccaugc agcuccugaa gauccgcucc ggugacaggc      420

cgaguuacgu ggaguugacg uucagccaac acguccggug ugaaugccgc ccccugaggg      480

agaaaaugaa gccagagcgg cgcaggccca aagggcgggg caagcgcagg cgggaaaaac      540

agcgcccaac ugauugucau cucugcggcg acgcagugcc caggcgguga ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  6960
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt7)

<400>  6960
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgacaggc agacugauac cgcccccagc ccauccuacc      120

aucugcuccc gggccggcgc aggacggugg acgcagccgc gagucggggg caaggucccg      180

agccagcccc cggcgggggc gucgaaggug ugggggcacg cggcguagcc cugaaguugu      240

ucgugcagcu gcucggcugc agcagguuug ggggugcagu cgugcgggcc ggcgaggcgg      300

aaccauccgg ggccgcacgc agugccagcu ccggcaggga ggaaccccag ccagaggagg      360

gugaagagga agaggagaaa gaagaggaac gggggccgca guggcgccug ggcgccagga      420

agcccggcag cuggacuggg gaggcagccg ugugugcgga uuccgcccca gcagcccggg      480

caccccaagc cuuggcccgc gcgaguggua ggggcgggcg ggucgcacgc aggggcgccg      540

aagagagcgg uccaccccac uccccgagcc ggcgcggcag ugccuccagg gcagggcccg      600

gccgggccag cgagaccaug aacuuccugc ucuccugggu gcacuggagu cuggcgcugc      660

uccuguauuu gcaucacgcc aaauggagcc aggcagcccc aauggcagaa ggggguggcc      720

agaaucauca cgagguagug aaguuuaugg acgucuacca gagguccuau ugccacccca      780

ucgaaacccu gguggauauu uuccaagagu acccagacga aaucgaguau auuuuuaaac      840

ccagcugugu gccacucaug cgcugcgggg gcuguugcaa cgaugagggu cuggaaugug      900

ucccgacuga ggaaaguaau aucaccaugc agauuaugcg gaucaagccc caucagggcc      960

agcacaucgg ggagaugucc uuccugcaac auaacaagug cgaauguagg cccaaaaagg     1020

accgcgcccg gcaggagaaa aagagcguga ggggcaaagg gaagggccag aaacgcaagc     1080

ggaagaaaag uagguacaag uccuggagcg uauauguggg ugcccggugc ugcuugaugc     1140

cauggagccu cccagggccc cacccgugug gcccaugcuc cgagcgcagg aaacaccugu     1200

uuguccaaga uccccagacg uguaagugca guuguaaaaa uacugacagc cggugcaagg     1260

cacgccagcu ggaacucaac gagaggaccu gucggugcga uaagcccagg cgcugaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  6961
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt7)

<400>  6961
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccugc ucagcugggu gcacuggucc cuggccuugc      120

ugcucuaccu gcaucacgca aaguggaguc aggccgcgcc cauggccgag ggcggggguc      180

aaaaucauca cgaagucgug aaauuuaugg acguauauca gaggagcuac ugccauccaa      240

ucgagaccuu gguggauauu uuccaggaau auccggacga gaucgaauac auuuuuaagc      300

ccuccugugu cccacugaug cggugcggcg gguguugcaa cgaugagggc cucgagugug      360

ugcccacuga agagaguaau aucaccaugc agauuaugcg caucaaacca caccaagguc      420

agcacaucgg ggaaaugagc uuccugcagc auaacaagug cgaguguagg cccaaaaagg      480

accgggcacg ccaggagaag aaauccguga ggggcaaggg caaagggcaa aagcggaaac      540

gcaagaaaag cagguauaag uccuggagug ucuacguggg ugcccggugc ugucugaugc      600

cauggagccu cccgggcccc cacccaugcg ggcccugcuc cgaacgcagg aagcaucugu      660

uuguacagga uccacagacg uguaaaugca gcuguaagaa uacugacagu cggugcaaag      720

cacgccaguu ggagcugaac gaaaggaccu gucggugcga uaagcccagg cgcugaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  6962
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt7)

<400>  6962
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcccccugc ucaggcggcu guugcuggcc gcacuccugc      120

aguuggcccc agcgcaagcc ccgguguccc agcccgacgc accaggccac cagcgcaagg      180

ucgugaguug gaucgaugua uacaccaggg ccacuugcca gccccgggag guggucgugc      240

cacugaccgu ggaacucaug gggacggucg caaaacaacu ggugcccagc uguguaacug      300

ugcagcgcug cgguggcugu ugcccagacg augggcugga gugugucccg accggccagc      360

aucaggugag gaugcaaauu cucaugaucc gguaucccuc cagucagcug ggugaaauga      420

gcuuggagga acacucccag ugcgaguguc gcccaaagaa aaaggacagc gccgugaaac      480

ccgauagggc ggccacccca caucaccggc cccagccgcg cuccgucccc gggugggaca      540

gugcaccagg cgcccccagc ccagccgaua uuacucaucc caccccagca ccgggccccu      600

ccgcccacgc ggccccaagc acgaccagug cacugacucc cgggccagcc gcagccgccg      660

cggacgcagc cgccuccagc guggcaaagg guggcgccug aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  6963
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt7)

<400>  6963
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caucugcucg gcuucuuuag cguggccugc ucccuguugg      120

cagccgcgcu gcuccccggg ccaagggagg ccccggcagc cgcagccgcg uucgaaagug      180

gucuggacuu gagcgaugcc gagcccgacg caggcgaagc caccgccuac gcauccaagg      240

aucuggagga acagcuccgg agugucagcu ccguggacga gcugaugacu guacuguauc      300

cagaguacug gaaaauguau aagugucaac uccgcaaagg gggcuggcag cacaacaggg      360

aacaggccaa ucugaacagc cggaccgagg aaacgaucaa guuugcggcc gcacacuaca      420

auacugagau uuugaaaucc aucgauaacg aguggcgcaa gacccagugc augcccaggg      480

aaguguguau ugacgucggu aaggaguucg ggguggccac caauacuuuc uucaaaccac      540

ccugcgugag ugucuaucgg uguggcggcu gcuguaacag cgaagggcug caaugcauga      600

auaccuccac gagcuaccuc aguaagacuc uguuugagau caccgugcca cugucccagg      660

guccgaaacc cguaacuauu agcuucgcaa accauaccuc cugucgcugc augaguaagu      720

uggaugugua uaggcagguc cacagcauca uccggcgcuc ccucccagcc acccugcccc      780

agugccaagc cgcgaauaaa acguguccaa cuaacuacau guggaauaac cauauuugua      840

ggugccuggc acaggaagac uuuauguuca gcagugaugc cggcgacgau uccaccgacg      900

gguuucacga uaucugcggc cccaauaagg agcucgacga ggaaacuugu cagugcgugu      960

gucgggccgg ucugcgcccg gcaagcugcg ggccccacaa agaguuggac aggaacaguu     1020

gucagugcgu gugcaagaau aagcuguucc caucccaaug uggcgccaac cgggaauuug     1080

augagaauac cugccagugu gucugcaaac gcaccugucc caggaaccag ccacucaacc     1140

ccggcaagug cgcgugugaa ugcacugaga gcccacaaaa augucugcug aaggggaaaa     1200

aguuucauca ccagacgugc agcuguuacc ggcgcccgug caccaauagg cagaaggccu     1260

gcgagcccgg uuucuccuau agugaagagg ugugucggug cguaccaagc uacuggaaaa     1320

ggccccagau guccugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  6964
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt7)

<400>  6964
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagggagu ggguggucgu gaacguauuc augaugcugu      120

augugcagcu cguccaaggc agcuccaaug aacacgggcc cgugaagcgg aguagccagu      180

ccacccugga gcgcagugaa cagcagauca gggccgcaag cuccuuggag gaacugcucc      240

ggauuacuca uagcgaggac uggaaacugu ggcgcugcag guugcggcug aaguccuuua      300

ccaguaugga uagccgcucc gccagccaca ggaguacgcg guucgcggcc acuuuuuacg      360

acaucgagac ccucaaagug auugaugaag aguggcaacg cacccagugu uccccaaggg      420

aaacuugcgu cgagguggca agcgagcugg guaaguccac caacacguuc uuuaaaccgc      480

ccuguguaaa uguguuccgg ugcggcgggu guugcaacga agagagucug aucuguauga      540

auacuagcac cuccuauauu agcaagcagc ucuuugaaau caguguccca cugacuuccg      600

ugcccgaguu ggugccaguc aagguggcca accauaccgg cugcaaaugu cugcccaccg      660

caccacgcca cccguacagc aucauuaggc ggaguaucca gauucccgaa gaggaccgcu      720

gcucccauag caagaaacuc ugcccaaucg auaugcugug ggacagcaau aaguguaaau      780

gcguacugca agaggaaaac cccuuggccg guacggagga ucacucccac cuccaggaac      840

cagcgcugug ugggccccau augauguucg acgaggauag gugcgaaugu gugugcaaga      900

cuccgugucc caaagaccug auucagcacc caaagaauug caguuguuuu gagugcaagg      960

agagccucga aaccugcugu cagaaacaua agcuguucca ccccgauacu ugcuccugug     1020

aggaccggug cccauuucac acccgccccu gugccagcgg caaaaccgca ugcgccaagc     1080

auuguagguu cccaaaagaa aagcgggccg cacaaggccc gcacaguagg aagaaccccu     1140

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  6965
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt8)

<400>  6965
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg aaaccggcuu cgaacacucc ggccucuggg      120

ucuccguccu cgccggccua cuacuaggcg ccugccaagc ccaccccauc cccgacucau      180

ccccacuucu acaauucggc ggacaaguca gacaacgaua ccucuacacc gacgacgccc      240

aacaaacaga agcccaucuc gaaauaagag aagacggcac cgucggcggc gccgccgacc      300

aaucccccga aucccuacuc caacucaaag cacucaaacc cggcgucauc caaauccucg      360

gcgucaaaac cucccgcuuc cuaugccaac gccccgacgg cgccuuauac ggcucccuac      420

acuucgaccc cgaagccugc ucuuuucgcg aacuccuacu cgaagacggc uacaacguau      480

accaauccga agcccacggc cuaccccuac accuccccgg caacaaauca ccccaccgcg      540

acccagcccc acguggcccc gcacgcuucc ucccacuacc aggccuccca cccgcccucc      600

ccgaaccacc cggcauccuc gcaccccaac cacccgacgu aggcuccuca gacccccucu      660

ccauggucgg ccccucccaa ggccgcucac ccucauacgc cucauaagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  6966
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt8)

<400>  6966
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuccuucc caccccuccu ccuacuucuc uucuggggcg      120

uaguauccca cuccuucccc gccacacuag aaacccaaga acaagacgua gaccuggucc      180

aaaaauaccu agaaaaauac uacaaccuca agaacgaugg acgacaaguc gaaaaacgcc      240

gcaacuccgg cccggucgua gaaaagcuaa aacaaaugca agaguucuuc ggccuaaaag      300

ucacuggcaa accagacgcc gaaacccuca aagucaugaa acaaccacga ugcggcgucc      360

cagacgucgc acaauucguc cucacagaag gcaacccccg augggaacaa acccaccuca      420

ccuaccgaau ugaaaacuac acaccugacc ugcccagagc cgacguagac cacgccauag      480

aaaaagccuu ucaacucugg ucaaacguca caccccucac cuuuaccaaa gucucggaag      540

gccaagccga cauaaugauu agcuucguuc gaggcgacca cagagacaac ucccccuucg      600

acggacccgg cggcaaccuc gcccacgccu uccaacccgg cccggguaua ggcggagaug      660

cacauuucga cgaagacgaa cgcuggacaa acaacuucag agaauacaac cuccaccgug      720

uagcagccca cgaacuaggc cacucacucg gacucucaca cagcaccgac aucggagccc      780

uaauguaccc auccuacacu uucuccggag acguucaacu cgcccaagac gacaucgacg      840

gcauccaagc aaucuacggc cgcucccaaa acccaguaca acccaucgga ccacagacuc      900

ccaaagccug cgacuccaaa cucaccuuug acgcaaucac caccauccga ggcgaaguca      960

uguucuucaa agaccgcuuc uacaugcgca cgaaccccuu cuacccagaa gucgaacuca     1020

acuucauauc agucuucugg ccccaacuac caaacggccu ugaagcagca uacgaauuug     1080

ccgacagaga cgaaguccgc uucuucaaag gaaacaaaua cugggccguc caaggccaaa     1140

acguccuuca cggcuacccc aaggacauau acuccuccuu cggcuucccc cgaacaguca     1200

aacacaucga cgcggcacug uccgaagaaa auaccggcaa gacauacuuc uucgucgcca     1260

acaaauacug gcgguacgac gaauacaaac gauccaugga ccccggcuac cccaaaauga     1320

uagcacacga cuucccggga aucggccaca aagucgaugc aguauucaug aaagacggau     1380

ucuucuacuu cuuccacggc acacgccaau acaaauucga ccccaaaaca aaacgcaucc     1440

ucacccucca gaaagccaac agcugguuca auugccgcaa aaacuaagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  6967
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt8)

<400>  6967
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuccuucc cuccccuacu acuccuacua uucuggggag      120

ucguaucaca cuccuucguc cucaccgaag gcaacccucg augggaacaa acccaccuca      180

cuuaccgaau cgagaacuac acccccgacc ucccacgagc cgacgucgac cacgccaucg      240

aaaaagccuu ucaacuaugg uccaacguca caccccucac cuucacuaaa guaagcgaag      300

gccaagccga caucaugauc agcuucgucc gcggagacca ccgagacaau ucccccuucg      360

acggcccagg aggcaaccua gcccacgccu uucaaccagg acccggcaua ggaggcgacg      420

cccacuucga cgaagacgaa cgauggacaa acaacuuccg cgaauacaac cuccacagag      480

uagccgccca cgaauuaggc cacucccuag gacucucaca cucaaccgac auaggugccc      540

ucauguaccc cuccuacacc uucagcggcg acguccaacu agcccaagac gacaucgacg      600

gcauacaggc caucuacggc cgaucucaaa auccagucca acccauagga ccacagacac      660

caaaagccug ugacuccaaa cucaccuucg acgccaucac caccauacgc ggagaaguca      720

uguucuuuaa agacagauuc uacaugcgua ccaaccccuu cuacccagaa guagaacuaa      780

acuucauauc ugucuucugg ccacaacucc ccaacggccu agaagcagca uacgaauuug      840

cugacagaga cgaaguacga uucuucaaag gcaacaaaua cugggccguc caaggccaaa      900

acguacuaca cggcuaccca aaagacaucu acuccuccuu cggcuucccc cgcacaguca      960

aacacaucga ugccgcacuc agcgaagaaa acaccggaaa aaccuacuuc uucgucgcca     1020

acaaauacug gcgauacgau gaauacaaac gauccaugga ccccggauac cccaaaauga     1080

ucgcccacga cuuccccgga auaggccaca aagucgacgc aguuuucaug aaagacggcu     1140

ucuucuacuu cuuccacgga accagacaau acaaauucga ccccaaaacc aaacgcaucc     1200

ucacccucca aaaagccaac uccugguuca acugccgcaa aaacuaagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  6968
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt8)

<400>  6968
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaaaaaca uccucaaaau acucauggac ucguauucua      120

aggaauccaa aauccaaacc gucagacgcg ucacuagcgu cucccuccuc gcgguguacc      180

uaacuaugaa uacguccagc cuaguccucg caaagccuau cgagaacacc aacgacacca      240

gcauuaaaaa cguugagaag cuacgcaacg cgccaaacga ggaaaacuca aagaaagucg      300

aagacagcaa aaaugacaaa guagagcacg uuaaaaacau agaagaagcc aagguggaac      360

aaguagcacc ggaagucaaa agcaaaagua cccuacgcag cgccagcauu gccaacacca      420

acagcgaaaa guacgacuuc gaguaucuua acgggcucag cuacacagaa cuaacaaacc      480

ugaucaaaaa cauaaaaugg aaccaaauaa acgguuuguu caacuacagc acagggucac      540

aaaaauucuu cggcgauaaa aaccgcgucc aggccaucau aaacgcccua caagaaagcg      600

gccgcacaua caccgcgaac gacaugaagg gaauagaaac cuucacggag guauuaaggg      660

cgggguucua ccuaggcuac uacaaugacg gacucucaua ccuaaacgac cgcaacuucc      720

aagacaagug cauccccgcc augauagcca uacagaaaaa cccaaauuuu aaacucggca      780

cggccgucca agacgaaguu auaacauccu uagggaaacu caucggaaac gccucggcca      840

acgccgaagu ggugaacaac ugcguccccg uacuuaagca auuccgcgaa aaccuaaacc      900

aauacgcacc cgacuacguu aaggggaccg cggucaacga auugauaaaa ggaaucgagu      960

ucgacuuuag cggagcagca uaugaaaagg acgugaagac aaugcccugg uacggcaaga     1020

uugauccguu cauuaacgaa cucaaggccc ucggacuaua cggaaacaua accucagcaa     1080

ccgagugggc uucagaugua ggcaucuacu accugagcaa guucggccua uacagcacca     1140

accgcaacga cauugugcaa aguuuagaaa aagcagucga cauguacaag uacggcaaga     1200

uugcauuugu agcgauggaa cgaauaacgu gggacuacga cggcaucggc uccaacggaa     1260

agaaagucga ccacgacaag uuccuggaug acgccgagaa gcacuaccuc cccaagacau     1320

acaccuucga caacggcacc uucaucaucc gagccggcga caaaguaucg gaagaaaaga     1380

ucaagagacu auacugggcc uccagagaag ucaaauccca auuccaccga gucgucggaa     1440

acgacaaggc ccuagaagua ggaaacgccg acgacguauu aacuaugaaa auuuuuaaca     1500

gcccagaaga auacaaauuc aacaccaaua uuaacggcgu aucaacagac aacggaggac     1560

uguacauaga accccgaggg acauucuaca cauacgaacg gaccccacaa caauccaucu     1620

uuagccugga agaacucuuc agacacgaau acacccacua ccuacaggcc agauaccuag     1680

ucgacgguuu auggggacaa ggccccuucu acgagaaaaa ccgacucaca ugguuugacg     1740

agggcacagc cgaguucuuc gcaggaucaa caagaaccag cggcgugcuc ccgcgaaagu     1800

cgauccuugg cuauuuagcg aaagacaaag uagaccacag auacagccua aagaaaacac     1860

ugaacucagg cuacgacgau agcgacugga uguucuacaa cuauggcuuc gcaguagcgc     1920

acuaccuuua cgaaaaagac augccgacgu ucaucaagau gaacaaagca auacuaaaca     1980

ccgacguuaa aucguacgac gaaauaauca aaaagcuguc cgacgaugcc aacaaaaaca     2040

cagaauacca aaaccauauc caggaacucg cggacaagua ccagggggca ggaauccccc     2100

uagucucgga cgacuaccua aaagaccacg gcuacaagaa agcaagcgaa guauacagug     2160

agaucagcaa agccgccucc cuaacgaaca caucagugac ugcugagaaa agccaguacu     2220

ucaacaccuu cacacuccga ggaacuuaca cgggagaaac aucaaaaggc gaguucaaag     2280

acugggacga aaugagcaag aaauuagacg gcacccuaga aucacuagcg aaaaacucuu     2340

ggagcggaua caagacccuu accgcauacu ucacgaacua cagggucacc agugacaaca     2400

aagugcagua cgacgucgug uuccacggag uucuaacaga caacgccgac aucuccaaua     2460

acaaagcacc aaucgccaag gugacggggc caagcacagg agccgucgga cgaaacauag     2520

aguucucagg caaagacagc aaggacgaag acgggaagau aguaaguuac gacugggacu     2580

ucggugacgg agcaacaucc cgcgguaaga acagugugca cgcauauaag aaggccggaa     2640

cauacaacgu aacccuaaag guaacggacg acaaaggagc gacagcgacc gaaucguuua     2700

cuaucgaaau aaagaacgaa gacacgacca cuccaauaac aaaagaaaug gaaccaaacg     2760

augacaucaa agaagccaac ggcccuauag ucgaaggugu aaccguaaaa ggcgaccuca     2820

acggcuccga cgacgcagac acguucuacu ucgacgugaa agaagacggg gacguaacaa     2880

ucgaacuccc cuacuccggc uccucaaacu ucaccuggcu aguauacaag gaaggggacg     2940

aucaaaacca caucgcaagc ggaaucgaua aaaacaauag uaaaguaggg accuucaaau     3000

cgacaaaggg aaggcacuac gucuucauuu acaagcacga cagcgccagc aacauaaguu     3060

acuccuuaaa caucaaagga cuaggcaacg aaaaacuuaa ggaaaaagag aacaacgacu     3120

caagcgacaa agcgacugua aucccaaacu ucaauacgac aaugcaaggu ucccuccucg     3180

gagacgacuc acgggacuac uacagcuucg aagucaagga agaaggcgaa gugaacaucg     3240

aacuggacaa aaaggacgag uucggcguaa ccuggacccu gcaccccgaa agcaacauca     3300

acgacaggau caccuacggc caaguagacg gcaacaaagu cagcaacaaa gucaaacucc     3360

gccccggcaa guacuaccua cuggucuaca aguacagcgg cucaggaaac uacgaacucc     3420

gcgucaacaa guaaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  6969
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt8)

<400>  6969
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguca ccuucauaag ccuccucuuu cuguucagca      120

gcgcauacuc aauagccaac accaacucag aaaaauacga cuucgaauac cuaaacggcc      180

uaagcuacac cgaacuaacc aaccucauca aaaacauaaa auggaaccaa auaaacggcc      240

uauucaacua cagcaccggc agucaaaagu ucuucgguga caagaaccgc guccaggcga      300

uaaucaacgc ccuacaagaa uccggccgca ccuacacagc caacgacaug aaaggcauag      360

aaacauucac ggaaguacua cgugcuggau ucuaucuagg cuauuauaac gacggacuga      420

gcuaccuaaa cgacaggaac uuucaagaca aaugcauccc cgccaugaua gcaauccaga      480

aaaaucccaa cuuuaaacuc ggaacggcgg uccaagacga ggugaucacg ucacuuggaa      540

aacucauagg aaacgcgagc gccaacgccg agguaguaaa uaacugcgua ccaguccuga      600

agcaauuccg ugaaaaucuu aaccaauacg ccccagacua cguaaaagga acugcgguca      660

acgagcucau aaaaggaaua gaguucgacu ucagcggagc cgcauaugaa aaagacguaa      720

agaccaugcc cugguacggc aaaauagacc cguucaucaa cgaacucaag gcacuaggcc      780

uauacggcaa caucacaagc gccaccgaau gggccucaga cgucgggauc uacuaccuau      840

caaaauucgg acucuacagc acaaaccgaa acgacaucgu acaaucccua gaaaaagcag      900

ucgacaugua caaauacgga aagaucgcau ucgucgccau ggagcgcauc acgugggauu      960

acgacggaau aggcucaaac ggaaagaaag ucgaccacga caaauuccuc gacgacgcag     1020

aaaaacacua ccugccgaaa acuuauacgu uugacaacgg caccuucauu auccgcgcgg     1080

gcgacaaagu aucugaggaa aagaucaaac gacuauacug ggcuagccga gaaguaaaaa     1140

gccaguucca ccgaguaguc ggaaacgaua aggcgcucga aguaggaaac gccgacgacg     1200

uccuuacuau gaagaucuuc aacagccccg aagaauacaa auucaacacu aacaucaacg     1260

gcguauccac agacaacgga ggccuauaca ucgaaccuag gggcaccuuc uacaccuacg     1320

aacgcacccc acaacaauca aucuucucuc uugaagaacu cuuccggcac gaguacaccc     1380

acuaccuaca agcacgauac cucgucgacg gccuaugggg ccaaggacca uucuacgaga     1440

aaaacagacu caccugguuu gacgaaggga ccgcugaguu cuucgccggc agcacaagaa     1500

caucaggagu ccucccccga aagagcaucc uaggauaccu ggccaaggac aagguagauc     1560

accgcuacag ccuaaagaag acacuaaaca gcggcuacga cgacuccgac uggauguucu     1620

auaauuacgg cuucgcggua gcacacuacc uguaugaaaa agacaugcca accuucauca     1680

aaaugaacaa agcaauacua aacaccgaug ucaaaagcua cgaugaaauu aucaaaaagc     1740

ugagcgacga cgcaaauaaa aacaccgaau aucaaaacca cauccaggaa cucgccgaca     1800

aauaccaagg cgcagggauc ccccuggugu cagacgacua ccuaaaagac cacggcuaca     1860

agaaagccuc ggaagucuac uccgaaauca guaaagcagc cagccuaacc aauacaucag     1920

uuacagccga aaagagccag uacuucaaca cauucacacu gaggggcacc uacacaggcg     1980

aaacuuccaa aggggaguuc aaggacuggg acgaaaugag caagaagcuc gacggcaccc     2040

ucgaaucacu cgcuaaaaau ucauggucgg gauacaagac uuuaacggca uacuucacga     2100

acuaccgagu gacaagcgac aacaaagucc aauacgacgu cgucuuucac ggcguccuga     2160

ccgacaacgc agacauaucc aacaacaaag caccgaucgc aaaagucacc ggaccgagca     2220

ccggggcagu cgggagaaac aucgaguucu caggcaaaga cuccaaggac gaggacggca     2280

aaaucgucag cuacgacugg gacuucggag acggcgcaac aagccggggc aagaacucag     2340

uccacgccua caagaaagca ggaaccuaca acguaacacu aaaaguaacc gacgacaaag     2400

gggcaacagc caccgaaucg uucaccauag aaaucaaaaa cgaagacacc accaccccca     2460

uuacgaaaga gauggaaccg aaugacgaca ucaaagaggc uaacggcccu aucgucgagg     2520

gcguaaccgu aaaaggcgac cuuaacggau cggaugacgc agacaccuuc uacuucgacg     2580

uaaaagaaga uggcgacguc acuaucgagc ucccauacuc cggcuccagc aacuucaccu     2640

ggcucguaua caaggaaggu gacgaccaga accacaucgc uucggggaua gacaaaaaua     2700

acucuaaagu uggcacauuc aagagcacaa aaggccggca uuacguuuuc auauacaagc     2760

acgacuccgc uucaaacauc aguuacagcc ucaacaucaa gggacuggga aaugagaagc     2820

ucaaagagaa agagaacaac gacuccuccg acaaagccac gguaauaccc aacuucaaua     2880

cgaccaugca agguucucua cucggcgacg acagcaggga cuacuacucg uuugagguca     2940

aggaggaagg cgaaguaaac auagagcuug acaagaaaga cgaguucggu gugacgugga     3000

cacuacaccc agaguccaac auaaaugaca gaauaacaua cggccaggua gacggcaaca     3060

aggugagcaa caaagucaaa cuccgacccg guaaauacua ccuauuaguc uacaaauacu     3120

ccggaagcgg gaacuacgag cuacgcguca auaagugagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  6970
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt8)

<400>  6970
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguaa ccuucauauc ccuccuguuc cuauucucau      120

cagcauacag caugaagaaa aacauccuca aaauccuaau ggauagcuac ucaaaggaaa      180

guaaaaucca gacgguucgc cgagugacgu ccgucucccu ucuagcagua uaccucacua      240

ugaacacaag cucccuaguc cuggccaaac ccauugaaaa caccaacgac accucuauaa      300

agaacguaga aaaacuccga aacgccccaa acgaggaaaa cucaaagaaa guagaggauu      360

cuaaaaacga caaaguagaa cacgucaaaa acauagaaga ggccaaagua gaacaagucg      420

ccccggaagu caaauccaaa agcacgcugc ggucggcguc ucgccggcga cggaaacgca      480

uagcaaacac aaacucggaa aaauacgacu ucgaauaccu caacggacuc agcuacaccg      540

aacugacgaa ccucaucaaa aacaucaaau ggaaccaaau caacggacug uucaacuacu      600

ccacaggauc ccaaaaguuc uucggcgaca aaaaccgagu acaggcgauc auaaaugccc      660

ugcaggaaag cggcagaacu uauaccgcaa augacaugaa gggcaucgaa acguucaccg      720

agguccugag agcgggcuuc uaccuaggau acuacaacga cggacucagc uaccucaacg      780

accgcaacuu ucaggauaaa ugcauaccgg caaugaucgc aauccagaaa aaccccaacu      840

ucaaacuugg aacagcggua caagaugagg ucaucacauc gcugggaaag cuaauaggaa      900

acgccuccgc aaacgccgaa guagucaaca acugcguccc uguauuaaaa caauuccgug      960

agaaccucaa ccaauacgcc cccgacuacg ucaaaggcac cgccgucaac gaacugauaa     1020

agggcauaga guucgacuuc aguggagcag cauacgaaaa agacgucaag accaugcccu     1080

gguacggcaa aaucgauccc uucaucaaug aacucaaagc gcuuggccuc uacggaaaca     1140

uaaccucugc cacagaaugg gcaagcgacg ucggaauaua uuaccuaucc aaauucggcc     1200

ucuacagcac aaacagaaac gacauaguac agucacucga aaaagcuguc gacauguaca     1260

aauacggaaa gauagcauuc gucgcaaugg aacgcauaac augggacuac gacggcauag     1320

gguccaacgg caagaaagua gaccaugaca aguuccuaga cgacgcagaa aaacacuacc     1380

ugcccaagac cuacaccuuc gacaacggaa ccuucauaau ccgagcaggc gacaaaguaa     1440

gcgaagagaa aauaaaacgc cuauacuggg ccagucgaga agucaaauca caauuccacc     1500

gagucguagg caacgacaag gcacuagaag ugggaaacgc cgacgauguc cuaacuauga     1560

aaaucuucaa cagcccggaa gaauacaaau ucaacaccaa caucaacggg gucucaaccg     1620

acaacggcgg gcuguacaua gagccgcgcg gcacguucua cacguacgag cgcacacccc     1680

aacaaagcau cuuuucgcua gaagaacuuu uccgacacga auauacccac uacuuacagg     1740

cucgauaccu cguagauggc cuauggggcc aaggcccauu cuacgaaaag aacagacuca     1800

ccugguucga cgaaggaacc gcagaguucu ucgcaggauc gaccaggacg agcggcgucc     1860

ucccaaggaa auccauacuu ggauaccucg caaaagauaa gguagaccac cgguacucac     1920

uuaaaaagac ucucaacuca ggauacgacg acuccgacug gauguucuac aacuacggcu     1980

uugccguggc ucacuaucug uacgaaaagg acaugcccac cuucaucaag augaacaaag     2040

ccauccucaa caccgacgua aaaagcuacg acgaaauaau caagaaacuc ucagacgacg     2100

cgaauaaaaa cacagaauac caaaaucaca uacaagagcu cgccgacaaa uaccagggcg     2160

cggggauacc gcucgucucu gacgacuacc ucaaagacca cggguacaag aaagccagcg     2220

aggucuacag ugaaaucagc aaagccgccu cgcuaaccaa caccagcgua acggcggaga     2280

aaagccagua cuucaacacc uucacacuaa gaggaaccua uaccggugag accagcaaag     2340

gcgaguucaa ggacugggac gaaaugucca agaaauuaga cgggacccua gaaucgcugg     2400

ccaaaaacuc cuggaguggg uauaagaccc uuaccgcgua cuucacaaac uacagaguga     2460

ccagcgacaa uaaaguccag uacgaugucg uguuccacgg cgugcuaaca gacaaugcag     2520

acaucucaaa caacaaagcc ccaaucgcca aagucacggg acccagcaca ggcgccguag     2580

gccgcaacau cgaauuuuca gguaaggauu caaaagacga agacggcaag aucgucagcu     2640

acgacuggga cuucggagac ggcgccacca gcagagggaa aaacucagua cacgcguaca     2700

agaaggccgg gaccuacaac gucacccuaa aaguuacgga ugacaaaggc gccacagcca     2760

cggaauccuu caccauagaa aucaagaacg aggacacaac uacccccaua accaaagaga     2820

uggagccaaa cgaugacaua aaagaagcua acggcccaau cguggaaggc guuacuguca     2880

aaggggaccu aaacggcuca gacgacgccg acaccuucua cuuugacgua aaagaagacg     2940

gggacgucac aauagaacuc ccauacuccg gaaguagcaa cuucaccugg cuaguguaca     3000

aggaagggga ugaucaaaac cacauagcau ccggcauaga caagaacaac ucaaaaguug     3060

ggaccuucaa aucgaccaaa ggccggcacu acguauucau cuacaaacac gacuccgcaa     3120

guaauauauc auacagccua aacauaaagg ggcugggaaa ugaaaaacuu aaggaaaaag     3180

aaaacaacga caguagcgac aaagcaacag ugauccccaa cuucaauaca accaugcaag     3240

gcucacuccu cggagaugac ucaagggacu acuacucauu cgaagugaag gaagaaggcg     3300

aagucaacau cgaacucgac aagaaggacg aguucggcgu caccuggacc cuccacccug     3360

aaucaaacau aaacgacagg aucaccuacg gccaaguaga cggaaacaaa gugucaaaca     3420

agguaaaacu cagaccgggg aaauauuacc uacuggugua caaauauucu ggaagcggaa     3480

acuacgaacu acgagucaac aaauagggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  6971
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt8)

<400>  6971
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuca aaauaauccu aaaccgaggc aaaaccauga      120

agcgcaaaug ccucagcaag agacucaugc ucgcaaucac cauggcuaca aucuucacag      180

uuaacucaac ucuccccauc uacgccgcgg uagacaaaaa caacgcaacc gccgccgucc      240

aaaaugaauc uaaacgauac acagucagcu accuaaaaac ccuuaacuac uacgaccucg      300

uagaccugcu cgugaaaacc gaaaucgaga accucccgga ccuguuccaa uauuccagcg      360

augccaaaga guucuacggg aacaaaacac gaaugucguu caucauggac gaaaucggac      420

gccgagcgcc ccaauacacc gagauugauc auaagggaau cccgacgcuc gucgaagucg      480

uccgagccgg guucuaucuc ggcuuccaca acaaggaacu caacgagaua aacaaacgcu      540

cuuucaagga acgcgucaua ccguccauac uugccauaca gaaaaacccc aauuucaagc      600

ucggaacaga aguacaagac aaaaucguau ccgccaccgg ccugcuagcc ggaaacgaaa      660

ccgcaccacc agaagucguc aacaacuuca cucccauccu ucaagacugc aucaagaaca      720

ucgacagaua ugcauuggac gaccuaaaau caaaagcacu guucaacguu cuagccgcgc      780

ccacauauga uauaaccgaa uaccucagag caacaaagga gaaacccgaa aacacucccu      840

gguacggcaa aaucgacggc uucaucaacg aacuaaagaa acucgcauua uacggcaaaa      900

ucaacgacaa caacaguugg aucauagaca acggcauaua ccacaucgcg ccacuaggaa      960

aacuacacuc uaacaacaaa aucggaaucg aaacacuaac cgaagucaug aagguauacc     1020

ccuaccugag caugcaacac cuucaaucug cagaucaaau caaacgacac uacgacagca     1080

aagacgccga gggaaacaag aucccauuag acaaauucaa gaaagaagga aaagagaaau     1140

acugcccaaa gaccuacacg uuugaugaug gcaaaguaau cauaaaggcc ggcgcacgcg     1200

ucgaggaaga aaaagucaaa cgccuguacu gggcgucaaa agaagucaac ucccaauucu     1260

uccgagucua uggcaucgac aaaccccucg aggaaggcaa ccccgacgac auacugacaa     1320

uggucauuua caacucgccu gaggaauaca aacugaacuc agugcuauac ggcuacgaca     1380

ccaacaacgg cggcauguac aucgaacccg aaggcacuuu cuucacuuac gagagagagg     1440

cccaagaauc cacguacaca cuagaagaac uuuuccgaca cgaguacacc cacuaccucc     1500

aaggccguua cgcagucccg ggacaauggg gacgaacgaa acucuacgac aacgacaggc     1560

ugaccuggua cgaagagggc ggggcggaac uauucgcagg gagcaccagg acaucgggga     1620

uacuucccag gaaauccauc gucuccaaca uccacaacac aacacgaaau aaucgguaua     1680

aacugagcga uaccguccac ucaaaauacg gcgcgucauu cgaguucuac aacuacgccu     1740

guauguucau ggacuacaug uacaacaaag auaugggaau ccucaacaaa uuaaacgacc     1800

ucgcuaagaa caacgacgua gacggcuacg acaacuacau aagagaccua uccucaaacu     1860

acgcucugaa cgacaaauac caagaccaca ugcaggaacg aaucgacaac uacgaaaacc     1920

ucaccguccc guucgucgcc gacgacuacc ucgugagaca cgccuacaaa aaccccaacg     1980

aaaucuacag cgagaucagc gaagucgcca aacucaagga cgcaaaaucc gaggucaaaa     2040

agucucaaua cuucagcacc uucacucuac gcggcucaua cacgggcggc gccuccaaag     2100

gcaaauuaga agaccaaaaa gccaugaaca aguuuaucga cgacagccuc aagaaacuug     2160

acaccuacuc guggaguggc uacaaaacuc uaaccgccua cuuuacaaac uacaaagucg     2220

acucguccaa ccgcgugaca uacgacguag ucuuccacgg guaccuaccg aacgagggag     2280

acagcaaaaa cagccucccc uacggaaaaa uaaacggcac auacaaggga accgaaaaag     2340

agaaaauaaa auucuccucc gaaggcucgu ucgaccccga ugguaagaua guauccuacg     2400

aaugggacuu cggagacggc aauaaaagca augaggaaaa cccagaacac ucauacgaca     2460

aaguagggac cuacaccguu aaauuaaaag ucacggacga caaaggagag ucgagcgucu     2520

caaccaccac cgccgagaua aaagaccuau ccgaaaacaa acuacccgua aucuauaugc     2580

acgucccaaa aucaggcgca cucaaucaaa agguugucuu cuauggaaaa ggcaccuacg     2640

acccggacgg cagcauagcg ggcuaccaau gggacuuugg cgacgguucg gacuucucgu     2700

cagagcaaaa cccuagccau guauacacca agaaaggaga auacaccgua acccugcgag     2760

ugauggauuc aucuggccaa augucugaga aaacaaugaa aauaaaaauc accgacccag     2820

uauaccccau cgguaccgaa aaagaaccua acaacaguaa agaaacugca agcggaccca     2880

ucguccccgg cauuccuguc ucaggaacca ucgaaaacac cagcgaucag gacuacuucu     2940

acuuugaugu aaucaccccc ggcgaaguca aaaucgacau caacaaacua ggauacggcg     3000

gagccacaug gguggucuac gacgagaaca auaacgccgu cucuuacgca accgacgaug     3060

gacaaaaccu cagcgguaaa uuuaaagcag acaagcccgg acgcuacuac auccaccuau     3120

acauguuuaa cggcuccuac augcccuauc gaauuaacau ugagggcuca guaggccgcu     3180

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  6972
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt8)

<400>  6972
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaagaaaau gccuauccaa acgccucaug cuugcaauaa      120

caauggccac aauauuuacc gucaacucca cccuaccaau cuacgccgcc guagauaaaa      180

acaacgcaac agcagccguc caaaacgaga gcaaacgaua caccguauca uaccucaaga      240

cccuaaacua uuacgaucua guggaccucc ucguaaagac ggagaucgaa aacuuaccgg      300

aucuauuuca auacuccucc gacgcaaaag aguucuacgg uaacaagaca cgaauguccu      360

ucaucaugga cgaaaucgga cggcgcgcac cccaauacac cgaaaucgac cacaaaggca      420

uacccacccu ugucgaaguu guacgagccg gcuucuacuu aggauuccac aacaaggaac      480

ucaacgaaau caacaaacgc uccuucaaag aacgagucau ccccuccauc cucgcuauuc      540

agaagaaccc aaacuucaag cucgggaccg agguacaaga uaagauaguc agcgccaccg      600

gccugcuggc cggcaaugag accgcgcccc cagagguagu aaacaauuuc accccaaucc      660

uacaagauug caucaagaau aucgaccgcu acgcccugga cgaccuaaaa uccaaggccc      720

ucuucaacgu gcuggccgcg cccaccuacg auaucaccga auaccucaga gcuaccaaag      780

agaaacccga gaacacuccc ugguauggca agauagacgg cuuuauaaac gaacucaaaa      840

agcuagcacu guacggcaag aucaaugaua acaauucaug gaucaucgac aacgggauau      900

accacauugc cccguuaggu aaacugcaca gcaacaauaa aauaggaauc gagacccuaa      960

cugaggucau gaaaguauau cccuaucuua gcaugcaaca ccuacaaucc gcggaccaaa     1020

ucaagcgcca cuacgacagc aaagacgcug aggggaacaa aaucccccug gacaaguuca     1080

agaaagaggg caaggagaaa uacugcccaa aaaccuacac cuucgacgac ggcaaaguca     1140

uaaucaaagc cggcgcgaga guagaggaag aaaaaguaaa gcggcucuac ugggccagca     1200

aagaagucaa cagucaauuc uuccgcgucu acggcaucga uaaaccacua gaagagggaa     1260

aucccgacga cauacuaaca augguaauau acaacagccc agaggaguac aaacugaacu     1320

ccguccuuua cggauacgau acaaacaacg ggggaaugua uauagaaccg gaaggcacau     1380

uuuucaccua cgaacgcgag gcccaggaau caacauauac acucgaggag uuauuccgcc     1440

acgaauacac ccacuaccua cagggacgcu acgcaguacc agggcagugg ggccgcacaa     1500

agcucuacga uaacgaccgc cuaacguggu acgaagaagg gggcgccgaa cucuucgccg     1560

gauccacccg caccagcggg auccuaccgc gaaagaguau agugagcaac auccauaaca     1620

ccacgcgcaa caaccgcuac aagcucucag acacagucca cagcaaguac ggagcaucgu     1680

ucgaguucua caacuacgca uguauguuca uggacuacau guacaacaaa gacaugggca     1740

uccucaacaa acucaacgau cucgcgaaaa auaacgacgu cgacggauac gacaacuaua     1800

uccgcgaccu cucauccaac uacgcacuca acgacaaaua ccaagaccac augcaggaac     1860

gaauagacaa cuacgaaaau uuaaccguac cauucguagc cgacgacuac cuaguacgac     1920

acgccuacaa aaacccuaac gaaaucuacu ccgagaucuc cgaaguugcc aaacucaaag     1980

augccaaauc agaagucaag aaaucccagu acuucagcac auucacucug agaggcagcu     2040

acacgggcgg cgcguccaaa ggaaaacuag aagaucagaa agccaugaac aaauucaucg     2100

acgacucucu aaagaaacuc gacacauacu cguggagcgg uuacaaaaca cugacugccu     2160

acuuuaccaa cuacaaaguc gacaguucaa aucgagucac cuacgacgug guauuucacg     2220

guuaccuacc caacgaaggg gacuccaaaa acucacuacc uuacggaaaa auaaauggga     2280

ccuacaaagg cacagaaaaa gagaaaauca aauucuccuc cgaaggcagc uucgacccug     2340

acggaaagau cgugagcuau gaaugggacu ucggcgacgg caacaaauca aacgaagaaa     2400

accccgagca uucauaugac aagguaggaa ccuacacagu caagcugaaa guaaccgacg     2460

acaaagggga aucaagcgua agcacuacca ccgccgagau caaggacuua agcgaaaaca     2520

aacugccagu aauuuauaug cacgucccaa aaucaggcgc ccuaaaccag aaggugguau     2580

uuuacgguaa agggacguac gaucccgacg gcagcaucgc cggcuaucag ugggacuucg     2640

gugacggcag cgacuucuca agcgaacaaa accccagcca cguuuacacg aaaaagggcg     2700

aauacacagu gacacuuaga gucauggaua gcucggguca aaugagugag aaaacgauga     2760

aaauaaagau caccgacccc guguacccca ucggcaccga aaaggaaccg aacaacucaa     2820

aagaaaccgc cuccgggccc aucguacccg ggaucccugu aucuggcaca auagaaaaca     2880

caagcgacca agacuacuuc uacuucgacg ucauaacccc cggcgaaguc aaaaucgaua     2940

ucaacaaacu cggauacggc ggagcgacau ggguagugua cgacgaaaac aacaacgcag     3000

uauccuacgc cacagacgac ggccaaaacc ucuccggcaa auucaaggcc gacaagcccg     3060

gacgauacua cauacaccuc uacauguuca acggaucaua caugcccuac cggauaaaca     3120

ucgaaggauc ggugggacgg uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  6973
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt8)

<400>  6973
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguca cauuuaucag ccuccuuuuc cuuuucagcu      120

cggccuacag cguccaaaac gaaaguaaaa gauauaccgu auccuaucuc aaaacuuuaa      180

acuauuacga ccuaguagac cuccugguaa agacugaaau agaaaaccug ccagaccuau      240

uccaauacag cuccgacgcu aaggaguucu acgggaacaa aacccgcaug uccuucauca      300

uggacgaaau cgggcgacgc gcaccacagu acaccgaaau agaccacaaa gggauuccca      360

cucuagucga ggugguacga gccggauuuu accuuggauu ccacaacaaa gaacucaacg      420

aaauaaauaa gcgaucauuc aaagagcggg uuaucccaag cauacuggca auccaaaaga      480

auccaaacuu caaacuuggc acagaagucc aggacaaaau agucuccgcc accgggcucc      540

ucgccgggaa ugaaaccgca cccccagaag ucgugaauaa cuucaccccc auucuccagg      600

acuguauaaa gaacaucgac cgcuacgcac ucgacgaccu uaagucaaaa gcgcucuuua      660

acguccucgc ggcgccuaca uacgacauca cagaauaccu ucgcgcgacc aaggaaaagc      720

cagaaaacac cccaugguac ggaaaaauag acggguucau caacgaacua aagaaacuag      780

cgcuauacgg caaaaucaac gacaacaaca gcuggaucau ugacaacggc auauaucaca      840

uagcaccccu gggaaaacuc cacagcaaua acaagaucgg caucgaaacc cuaaccgaag      900

uaaugaaagu cuacccguac cucuccaugc agcaucucca gagcgccgac cagauaaaac      960

gacacuacga cucaaaagac gcagaaggua auaagauccc acuggacaag uucaaaaagg     1020

agggcaaaga aaaauacugc ccuaaaacau acaccuucga cgacggaaag guaauaauua     1080

aagccggagc acgaguagaa gaagaaaaag uaaaacgccu cuacugggcc ucaaaggaag     1140

uuaauucaca guucuuccga guguacggua uagacaaacc acuggaggag ggaaacccag     1200

augacauacu gacgauggua auauacaacu ccccggaaga auacaaacua aauucaguac     1260

uguacggaua cgacaccaac aaugggggaa uguacaucga accagaaggc accuucuuca     1320

ccuacgagcg cgaagcccag gagucgacau auacccuaga agaacuguuu cgccacgagu     1380

acacgcacua cuuacaaggg cgcuacgccg uccccgggca guggggccga accaaacugu     1440

acgacaacga ccgccucacc ugguacgaag aagggggagc agaacucuuc gcaggaucga     1500

cccgcaccag cggaauacuc ccccgcaaga guauagucag caacauccac aacaccacca     1560

ggaacaacag auacaaacuu ucagacaccg uucacagcaa guacggggcc uccuucgagu     1620

uuuacaacua cgcaugcaug uucauggauu auauguacaa caaagacaug ggaauacuaa     1680

acaaacucaa ugaccucgcc aaaaacaacg acgucgacgg cuacgacaac uacauccgag     1740

accucagcag caacuacgcc cuaaacgaca aauaucaaga ccacaugcag gagaggauag     1800

auaacuacga aaaucucacc gugccauucg uagccgacga cuaccucgua cgucacgccu     1860

acaaaaaccc caacgaaauc uacagcgaga ucucggaagu agcaaaacua aaagaugcua     1920

aaucagaggu gaagaaaucc caauacuucu cgaccuucac ucuccgcggc uccuacacag     1980

gaggagccag caaagguaaa cuagaggacc aaaaagcaau gaacaaauuc aucgacgacu     2040

cccucaagaa acucgauacc uacagcugga gcggauacaa aacguuaacc gcauauuuca     2100

ccaauuacaa aguggacagu uccaaccgag uaaccuacga uguaguguuc cauggcuacc     2160

uacccaacga gggcgacagc aaaaacucac uccccuacgg aaagaucaac gggacauaca     2220

agggcacgga aaaagagaaa aucaaauuca gcucagaagg cuccuucgac cccgacggca     2280

agauugucuc cuacgagugg gacuucgggg acggcaacaa aucgaacgag gagaacccag     2340

aacacagcua cgacaagguc ggcacguaca ccgucaagcu caaaguaaca gacgacaagg     2400

gggaauccag cguaagcacg acaacagcag aaaucaagga ccuauccgaa aauaaacuac     2460

cggugauaua caugcauguc ccuaaauccg gcgcucugaa ucagaaggug guauucuacg     2520

ggaagggcac guacgacccc gacggaucca uagcaggcua ccaaugggac uucggcgaug     2580

guucggacuu uucguccgag cagaacccaa gccacguaua cacaaagaaa ggggaguaua     2640

ccgucacacu ucgagucaug gacagcagug gccagaugag ugagaaaaca augaaaauca     2700

aaaucacaga ucccguuuac ccgaucggca cagaaaaaga accaaacaau uccaaagaga     2760

cggcgucagg cccaaucgug cccggaaucc ccguuucggg aaccauagag aacacaagcg     2820

accaagacua cuucuacuuc gacgucauca ccccaggcga gguaaaaaua gacauaaaca     2880

aacuaggaua cggaggcgca acaugggugg uauacgacga aaacaacaac gcggucagcu     2940

augcaacgga cgacggccaa aaccuaucag gaaaguucaa ggccgacaag cccggaaggu     3000

acuauauaca uuuguacaug uucaacggca gcuacaugcc cuacagaauc aacaucgaag     3060

gcagcgucgg ccgcugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  6974
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt8)

<400>  6974
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguga ccuucauauc acuccuuuuc cuauucucau      120

cagcauacuc gaugaaacgc aaaugccuca gcaaacgacu caugcuagcu aucaccaugg      180

ccacaauauu caccguaaac uccacccuac ccaucuacgc ggcaguggac aaaaacaacg      240

ccaccgccgc acgucgccgc cggaaacgcg uccaaaacga aaguaagcgc uauacgguga      300

gcuaccucaa aacucucaac uacuaugauc uaguagaccu ccuagucaaa acggaaauug      360

aaaaccuccc cgaccuauuc caguacucau cagacgcgaa agaguucuac ggcaacaaaa      420

cccggauguc cuucauaaug gacgaaaucg gaaggcgagc accccaguau accgagaucg      480

accacaaggg cauccccacg cucguagaag uaguuagagc aggcuucuac cucggguucc      540

acaacaaaga acuaaaugag aucaacaaac gcuccuucaa agaacgcguc auccccucaa      600

uacuagcaau ccagaaaaac cccaauuuca aacuaggcac cgagguacaa gauaaaaucg      660

uguccgcaac aggccuccug gcagguaaug aaaccgcgcc gccagaagua gucaacaacu      720

ucacacccau ccuucaggac ugcaucaaaa acauagacag auacgcacuc gacgaccuca      780

aaagcaaagc acuauucaac guccucgcag cacccacaua ugacauaacg gaauaccuua      840

gagcaaccaa agaaaaaccc gaaaacacac ccugguaugg gaaaauagac ggcuucauca      900

acgagcuuaa aaagcuggca cuuuacggga aaauaaacga caacaacagc uggaucauag      960

acaacggcau uuaccacauc gcaccccugg ggaaauugca cagcaacaac aaaaucggca     1020

uagaaacccu cacggagguc augaaaguuu acccauaccu gucaaugcaa caccuccaau     1080

ccgccgacca gaucaaacga cacuacgaca gcaaagacgc cgaaggcaac aagauaccac     1140

uagacaaguu caagaaagaa ggcaaagaaa aauauugccc uaaaaccuac acauucgacg     1200

acggaaaagu aaucauuaaa gccggcgccc guguagaaga agaaaagguc aaacgccuau     1260

acugggccag caaagaagua aauagccaau ucuuccgcgu auacgggaua gacaaaccgc     1320

uagaagaagg aaaccccgac gacauacuga ccaugguaau auauaacuca ccggaagaau     1380

acaaacucaa cagcguacua uacggcuaug acaccaauaa cggaggaaug uacaucgagc     1440

cagaaggaac auucuucacg uacgaacgug aagcacaaga auccacauac acccucgagg     1500

aacucuuccg ucacgaguac acccacuacc uacaggggcg auacgccgua cccggccaau     1560

ggggccgcac caaacuguau gacaacgacc ggcucaccug guacgaagaa gggggcgccg     1620

aacucuucgc cgguucgacc aggacuucag gaauacugcc ccgcaagagc aucguaagca     1680

acauccacaa uacaacccgc aacaaccgcu acaaacuauc agacacaguc cacuccaaau     1740

acggagcguc auuugaguuc uacaacuacg cuugcauguu uauggauuau auguacaaca     1800

aagauauggg gauccugaau aaacuaaacg accuagcgaa aaacaacgac guugacggcu     1860

acgacaacua cauacgugac cucucaucaa acuacgcccu aaacgacaaa uaccaggacc     1920

acaugcaaga acgcaucgac aauuacgaaa accuaacagu gccuuuuguc gccgacgacu     1980

accucguacg gcacgcuuac aaaaacccca acgaaaucua uucagaaauc ucagaagucg     2040

ccaaauuaaa agacgcuaaa uccgaaguca agaaguccca auacuucucc acauuuaccc     2100

ucagaggcuc auacaccgga ggcgcaucca aaggcaaacu ggaggaccaa aaagccauga     2160

acaaauucau cgaugacagu cuaaagaaac ucgacaccua cuccuggucc ggauacaaaa     2220

cgcuaacagc cuacuucaca aacuacaaag uagacagcuc caaccgaguc accuacgacg     2280

ucgucuucca ugguuaccuc cccaacgaag gugacagcaa aaauucacuc cccuacggca     2340

aaauaaacgg caccuacaaa ggcaccgaaa aggagaaaau caaauucuca ucggaaggca     2400

gcuucgaccc agacgggaag auaguaucgu augaauggga cuucggggac ggcaacaaau     2460

ccaaugaaga gaaccccgaa cauuccuaug acaaaguggg gaccuacaca guuaagcuaa     2520

aaguaaccga cgacaaaggc gaaucauccg uaucaaccac aacggccgag auaaaagauc     2580

uaagcgaaaa caaacucccc guaauauaca ugcacguccc uaaaucggga gcucucaacc     2640

aaaaagucgu auucuacgga aaaggaacau acgacccuga cggcuccaua gccggcuacc     2700

aaugggacuu uggcgacggc agcgacuucu ccagugagca aaaccccuca cacgucuaca     2760

cgaaaaaggg cgaauacacc gugacacuuc gcguaaugga cagcagcggc cagauguccg     2820

agaaaaccau gaaaaucaag auuaccgacc cagucuaccc cauaggcacc gaaaaggaac     2880

cgaacaauag caaggaaaca gccagcggcc caauaguccc ggggaucccc gucuccggca     2940

cgaucgaaaa cacuuccgac caggacuacu ucuacuucga cguaauaacc cccggcgaag     3000

uaaaaaucga caucaacaaa cuaggauacg gaggcgccac cugggucguc uacgaugaaa     3060

acaacaacgc cguauccuau gccacagacg auggccagaa cuugucaggc aaguucaaag     3120

cugacaagcc cggacgcuac uacauccacc uguacauguu caauggcucc uacaugccau     3180

accgaauaaa caucgaagga ucggucggac gcugaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  6975
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt8)

<400>  6975
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuauucgc augccuccuc ggagccgccu      120

ucgccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc ucuuacgaag      180

uccucacccc ccuaaaaugg uaccaaucaa uucgcccccc cuauccaucc uacggcuacg      240

aacccauggg cggcuggcua caccaccaaa uaauacccgu ccucucccaa caacaccccc      300

ccacccacac ccuccaaccc caccaccaca uccccgucgu ccccgcacaa caacccguca      360

ucccccaaca accaaugaug ccagucccag gccaacacuc uaugaccccc auccaacacc      420

accaacccaa ccuccccccc cccgcacaac aaccauacca accccaaccc guccaaccac      480

aaccccacca acccaugcaa ccccaacccc ccguccaccc caugcaaccc cucccacccc      540

aaccaccccu cccccccaug uuccccaugc aaccccuccc ccccaugcua cccgaccuaa      600

cccucgaagc cuggcccucc acagacaaaa caaaacgaga agaagucgac uaaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  6976
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt8)

<400>  6976
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccucccac cccaccccgg ccaccccgga uacauaaacu      120

ucuccuacga aguccuaaca ccccuaaaau gguaccaauc cauacgccca cccuaccccu      180

ccuacggcua cgaacccaug ggcggauggu aaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  6977
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt8)

<400>  6977
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccucccac cccaccccgg ccaccccggc uacauaaacu      120

ucuccuacga aguccucaca ccacucaaau gguaccaauc cauccgccca ccacccaugc      180

uccccgaccu cacccucgaa gccuggcccu ccaccgacaa aacaaaacgc gaagaagucg      240

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  6978
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt8)

<400>  6978
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg caccccgaac ccuaguccua cuccuauccg      120

gcgcccuagc ccucacccaa accugggcca ugccacuacc accccaccca ggccaccccg      180

gcuacaucaa cuucuccuac gaaguacuca caccacuaaa augguaccaa uccauccgac      240

cacccuaccc cuccuacggc uacgaaccca ugggcggcug guaaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  6979
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt8)

<400>  6979
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccguaaugg caccccgaac acucguacuc cuccucuccg      120

gagcacuagc ccucacccaa accugggcca ugccccuccc cccacacccc ggccaccccg      180

gcuacauaaa uuucuccuac gaaguccuca ccccccucaa augguaccaa uccauccgcc      240

ccccccccau gcuccccgac cuaacacucg aagccuggcc cucaaccgac aaaacaaaac      300

gcgaagaagu cgacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  6980
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt8)

<400>  6980
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccuauucgc augccuaguc ggcgccgccu      120

ucgccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uacucacccc acucaaaugg uaccaaucca ugauacgccc acccuacucc uccuacggau      240

acgaacccau gggcggcugg cuccaccacc aaauaauccc cgucguuucc caacaacacc      300

cccucaccca cacccuccaa ucacaccacc acauccccgu aguccccgcc caacaacccc      360

gaguccgcca gcaagcccuc augcccguac caggccaaca aucaaugacc cccacccaac      420

accaccaacc caaccucccc cuccccgccc aacaacccuu ccaaccccaa cccguccaac      480

cccaaccaca ccaaccaaug caaccccaac cacccgucca acccaugcaa ccccuucucc      540

cccaaccucc ccuaccaccc auguuccccc uccguccucu cccacccauc cuccccgacc      600

uccaccucga agccuggccc gccaccgaca aaaccaaaca agaagaagua gacugaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  6981
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt8)

<400>  6981
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuaccac cccaccccgg ccaccccggc uacauaaacu      120

ucuccuacga aguccucacc ccacucaaau gguaccaauc aaugauacga ccacccuacu      180

ccucauacgg cuacgaaccc augggcggcu gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6982
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt8)

<400>  6982
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cacaccccgg ccaccccggc uacauaaacu      120

ucuccuacga aguccuaaca ccacucaaau gguaccaauc caugauccgc ccccccccca      180

uacuccccga ccuccaccuc gaagccuggc ccgccacaga caaaaccaaa caagaagaag      240

ucgacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6983
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt8)

<400>  6983
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccacgcac acucguccuc cuacucucag      120

gagcccucgc acucacacaa accugggcca ugccacuccc accacacccc ggccaccccg      180

gcuacaucaa cuucucauac gaaguccuca ccccacucaa augguaccaa ucaaugauac      240

gcccacccua cuccuccuac ggcuacgaac ccaugggcgg augguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6984
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt8)

<400>  6984
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagucaugg caccccgcac ccucguccua cuacucuccg      120

gcgcccucgc ccucacccaa acaugggcca ugccacuccc accccacccc ggacaccccg      180

gcuacaucaa cuucucauac gaaguccuca ccccacucaa augguaccaa uccaugaucc      240

gacccccacc cauccuaccc gaccuccacc ucgaagccug gcccgccacc gacaaaacca      300

aacaagaaga agucgacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6985
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt8)

<400>  6985
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc augccuccuc ggcgccgccu      120

ucuccaugcc ucuaccaccc caccccggcc accccggcua cauuaacuuc uccuacgaag      180

uccuaacucc ccuaaaaugg uaccaaaaca ugauccgaca ccccuacacc uccuacggau      240

acgaacccau gggcggaugg cuccaccacc aaaucauccc cgucgucucc caacaaacac      300

cccaauccca cgcccuacaa ccccaccacc acauccccau gguacccgcc caacaacccg      360

guauacccca acaacccaug augccccucc ccggccaaca cucaaugacc cccacccaac      420

accaccaacc caaccuaccc cuacccgcac aacaacccuu ccaaccccaa ccaguccaac      480

cccaacccca ccaaccacuc caaccccaau cccccaugca ccccauccaa ccccuccucc      540

cacaaccacc ccucccaccc auguucucca ugcaaucacu ccuccccgac cucccccucg      600

aagccuggcc cgcaaccgac aaaaccaaac gcgaagaagu cgacuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6986
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt8)

<400>  6986
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuaccac cccacccagg ccaccccggc uacaucaacu      120

ucuccuacga aguccucaca ccacucaaau gguaccaaaa caugaucaga cacccauaca      180

ccucauacgg cuacgaaccc augggcggcu gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  6987
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt8)

<400>  6987
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuacccc cacaccccgg ccaccccggc uacauaaacu      120

ucucauacga aguacucacc ccacucaaau gguaccaaaa caugauccga caccccuccc      180

uccuccccga ccucccccuc gaagccuggc ccgccaccga caaaaccaaa cgcgaagaag      240

ucgacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  6988
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt8)

<400>  6988
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagucaugg caccccgcac acucguccuc cuacuaucag      120

gagcccucgc acucacacaa acaugggcca ugccccuacc accccacccc ggacaccccg      180

gcuacauaaa cuucuccuac gaaguccuaa caccccuaaa augguaccaa aacaugaucc      240

gacaccccua caccuccuac ggcuacgaac ccaugggcgg cugguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  6989
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt8)

<400>  6989
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccacgcac ccuaguccuc cuccuauccg      120

gcgcacucgc acucacacaa accugggcca ugccccuccc accacacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca caccccucaa augguaccaa aacaugaucc      240

gccacccauc acuccuccca gaccucccac ucgaagccug gcccgccacc gacaaaacca      300

aacgcgaaga aguagacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  6990
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt8)

<400>  6990
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uacucuucgc augccuccuc ggcgccgccu      120

ucuccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc uccuacaucc      180

gccacccaua caccuccuac ggcuacgaac ccaugggcgg cuggcuacac caccaaauca      240

uccccgucgu cucccaacaa acaccccaau cccacgcccu acaaccccac caccacaucc      300

caaugguccc cgcccaacaa ccaggcaucc cacaacaacc caugaugccc cuacccggcc      360

aacacucaau gaccccaacu caacaccacc aacccaaccu accccuaccc gcccaacaac      420

ccuuccaacc ccaacccguc caaccccaac cccaccaacc ccuccaaccc caauccccca      480

ugcaccccau ccaaccccuc cuaccccaac caccccuccc acccauguuc ucaaugcaau      540

cccuacuccc cgaccuaccc cucgaagcau ggcccgcuac agacaaaaca aaacgcgaag      600

aagucgacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  6991
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt8)

<400>  6991
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaccugga ucuucuucgc cugccuccuc ggcgccuccc      120

ucgcaaugcc ccucccaccc caccccggcc accccggcua caucaacuuc uccuaugaag      180

uacucacacc ccucaaaugg uaucaaaaca ugauccgcca ccccuacaca uccuacggcu      240

acgaacccau gggcggcugg cuacaccacc aaaucauacc cgucgucuca caacaaacac      300

cccaaucaca cgcccuccaa ccccaccacc acauccccau gguccccgcc caacaacccg      360

gcauccccca acaacccaug augccccuac caggacaaca cuccaugacc ccaacccaac      420

aucaccaacc uaaucucccc cuccccgccc aacaacccuu ccaaccccaa cccguccaac      480

cccaacccca ccaaccccuc caaccccaau cccccaugca cccuauccaa ccccuccucc      540

cccaaccacc ccucccaccc auguucucca ugcaaucacu ccuacccgac cucccccucg      600

aagccuggcc ugccaccgac aaaacaaaac gcgaagaagu cgacuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  6992
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt8)

<400>  6992
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uacucuucgc cugccuccuc ggcgccgcau      120

ucucaaugcc ccucccacca cacccaggcc accccggaua caucaacuuc uccuacgaag      180

uacucacccc acucaaaugg uaccaaaaca ugauccgaca ccccucacuc cuccccgacc      240

ucccccuaga agccuggcca gccaccgaca aaaccaaacg cgaagaaguc gacuaaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  6993
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt8)

<400>  6993
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccua ggcgcugccu      120

ucuccaugcc acucccaccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

accuauaccu cgaagccaua cgcaucgacc gcaccgcauu uguccuaacc ccacucaaau      240

gguaccaaaa caugauccga cacccauaca ccuccuacgg cuaugaaccc augggaggcu      300

ggcuacacca ccaaaucauc ccagucgucu cacaacaaac cccucaaucu cacgcccucc      360

aaccacacca ccacaucccc augguccccg cccaacaacc cggcaucccc caacaaccca      420

ugaugccccu ccccggccaa cacuccauga cccccaccca acaccaccaa cccaaccucc      480

cccuccccgc acaacaaccc uuccaacccc aaccagucca accccaacca caccaacccc      540

uucaacccca aucccccaug caccccaucc aaccccuccu accacaacca cccuuaccuc      600

ccauguuuuc uaugcaaucc cuccuccccg accucccccu cgaagccugg cccgccaccg      660

acaaaacaaa acgcgaagaa guagacuaag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  6994
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt8)

<400>  6994
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaccugga uccuauucgc cugccuccua ggagccgccu      120

ucucaaugcc ccuaccaccc caccccggcc accccggcua caucaacuuu uccuacgaag      180

uccucacccc acucaaaugg uaccaaaaca ugauacgcca ccccacaccc caaucccacg      240

cccuacaacc ccaccaccac auccccaugg uccccgccca acaacccggc aucccccaac      300

aacccaugau gccccucccc ggccaacacu ccaugacccc cacccaacac caccaaccca      360

accucccccu ccccgcccaa caacccuuuc aaccccaacc cguccaaccc caaccacacc      420

aaccacucca accccaaucc cccaugcacc caauccaacc ccuccucccc caaccacccc      480

ucccacccau guucucaaug caaucacuac uccccgaccu cccccucgaa gccuggcccg      540

ccaccgacaa aaccaaaaga gaagaagucg acuaaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  6995
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt8)

<400>  6995
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucucccac cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucaca ccccucaaau gguaccaaaa caugauccgc caccccuaca      180

ccucauacgg cuacgaaccc augggcggcu ggcuccacca ccaaaucauc cccgucgucu      240

cccaacaaac accccaauca cacgcacucc aaccccacca ccacaucccc augguccccg      300

cccaacaacc cggcaucccc caacaaccca ugaugccacu ccccggccaa cacucaauga      360

cccccaccca acaccaccaa cccaaccucc cacuccccgc acaacaaccc uuccaaccac      420

aacccguaca accccaaccc caccaaccac uccaacccca aucccccaug caccccaucc      480

aaccccuacu cccccaacca ccccuacccc caauguucuc aaugcaaucc cuccuccccg      540

accucccccu cgaagcaugg ccagccacag acaaaaccaa acgcgaagaa gucgacuaag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  6996
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt8)

<400>  6996
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaggcguug caagacuacc acuacucuua ggacuacuac      120

uacuaccgcg accaggacga ccccucgacc uagcagacua caccuaugac cucgccgaag      180

aagaugauag cgaaccgcua aauuacaaag acccguguaa agcagcagcu uuucuaggcg      240

acauagcccu ggacgaggaa gaccuucggg cguuccaagu acaacaggca guagauuuac      300

gccgacacac ggcucgaaaa ucaucaauca aagcagccgu uccaggaaac acgucaaccc      360

caagcuguca gucaacaaau gggcaacccc aacgcggagc gugcggacga uggcgaggcc      420

gcagcagguc ccgcagagca gccaccuccc gccccgaaag agucuggccc gauggaguaa      480

uaccguucgu aauaggcggc aauuucaccg gaucccagcg cgcggucuuc cgccaagcca      540

ugagacacug ggagaaacau accugcguga cauuccucga aagaacagac gaagacucau      600

acauaguauu caccuaccga ccgugcggcu gcugcagcua cguaggccgc agaggcggcg      660

ggccacaagc gaucagcauc ggcaaaaacu gcgacaaauu cggaauaguc guccacgaac      720

ucggccacgu aguaggcuuc uggcacgagc acacccgacc ugaccgagac cgacacguca      780

gcaucguaag agaaaacaua caaccagggc aagaauacaa cuuccugaaa auggagcccc      840

aagaagugga auccuuagga gaaaccuacg acuuugacuc aaucaugcac uacgcaagga      900

acacauucuc acgaggaaua uuccucgaca caauaguucc caaguacgaa gugaacgggg      960

uuaaaccucc gauuggccaa aggacaagac uaucaaaggg cgacaucgca caggcacgaa     1020

aacuguacaa augccccgca ugcggggaga cacuacaaga cagcaccggg aacuucucaa     1080

guccggaaua cccaaacgga uacagugcuc acaugcacug cguauggcgg auaagcguca     1140

ccccgggcga gaaaauaaua cuaaacuuca caagucugga ccuauaccgg agccgccuuu     1200

gcugguacga uuacguagaa guccgcgacg gauucuggcg caaagcgcca cugaggggac     1260

gcuucugcgg aucaaaacuc ccggaaccga uaguaucaac cgacucacgc cucugggucg     1320

aguucagaag cagcucaaac ugggucggaa aaggauucuu ugcaguguac gaagcuaucu     1380

gcggaggaga cguaaagaaa gacuaugggc acauacaaag ccccaacuac cccgacgacu     1440

accgcccuag caaaguuugc aucuggcgca uacaagucag cgaaggcuuc cacgucggcc     1500

ugacauucca gaguuucgaa auagaacgcc augacagcug cgccuacgau uaccucgaag     1560

uccgcgacgg ccacucggaa agcagcaccu uaaucggcag guacugcggu uacgaaaaac     1620

cagacgacau aaagagcacc ucgagccgac ucuggcuaaa auucguaagc gacggcagca     1680

uaaacaaagc gggcuuugca guuaacuucu ucaaagaagu ggacgaaugc uccaggccaa     1740

accgaggcgg gugcgaacaa agaugucuaa auacacucgg cagcuacaaa ugcagcugcg     1800

acccgggaua cgaacucgcc cccgacaaaa gaaggugcga agccgccugc ggaggguucc     1860

ucacaaaacu aaacgggagc aucacuucac cgggauggcc aaaagaauac ccaccaaaua     1920

agaacugcau cuggcaacuc gucgcaccca cccaauaccg caucagccua caauucgacu     1980

ucuucgaaac cgaaggcaac gacgucugca aauacgacuu cguugaaguc cgcuccggac     2040

uaacagcaga cagcaaacua cacgguaaau ucugcggcuc cgaaaagcca gaagucauaa     2100

caagccaaua caacaauaug agagucgagu ucaagagcga caacaccguc agcaaaaagg     2160

gauuuaaggc acacuucuuc ucagacaaag acgaaugcuc aaaagacaac ggcggcugcc     2220

aacaagacug cguuaacaca uucggcucau acgaaugcca augcagauca gguuucgugc     2280

ugcacgacaa caaacacgac ugcaaagaag ccggcugcga ccauaaaguu accagcacca     2340

guggaaccau aacaagcccc aacuggccag acaaauaccc aucgaagaaa gaaugcacgu     2400

gggcuaucuc cagcacaccc gggcaccggg ucaaacucac cuucauggaa auggauaucg     2460

aaagccaacc ggaaugcgca uacgaccauc uagaagucuu ugacggccga gacgccaaag     2520

ccccaguacu cggcagauuc ugcggaucca agaaaccaga accaguacuc gcgaccggga     2580

gccgaauguu ccuccgcuuc uacagcgaca acuccgugca acgcaaaggc uuccaagccu     2640

cccaugcgac ggaaugcggc ggacaaguuc gcgcggacgu caaaaccaaa gacuuauaca     2700

gccaugcaca guucggugac aacaauuacc ccggaggcgu agacugcgaa ugggucauag     2760

uagccgaaga aggauacggc gucgagcucg uauuccagac auucgaagua gaagaagaaa     2820

ccgacugcgg cuacgauuac auggaacuuu ucgacgggua cgacagcaca gcgccacgcc     2880

ucggacgcua cugcggauca ggcccgccag aagaaguaua cagcgcaggc gacuccgucc     2940

uagucaaauu ccauucugau gacaccauca caaagaaagg cuuccacuug agauacacaa     3000

guacaaaauu ccaagacacc uuacauucaa gaaaauaagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  6997
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt8)

<400>  6997
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgccggaa cucgcugccu ccuagcccuc cuacuccccc      120

aaguacuacu cggcggcgcc gccggccucg uucccgaacu cggacgacga aaauucgccg      180

ccgcauccuc uggaaggccc agcucccaac ccuccgacga aguucucucc gaguucgaac      240

uccgccuccu cucaauguuc ggccucaaac aacgccccac accaucacgc gacgcagucg      300

ucccgcccua caugcucgac cuauaccguc gucacucagg ccaacccgga ucccccgccc      360

ccgaccaccg ucucgaacgc gcagccucgc gcgccaacac aguccgcucc uuccaccacg      420

aagaaucccu cgaagaacua cccgaaaccu ccggcaaaac aacccgacgc uucuucuuca      480

accucagcuc cauccccaca gaagaguuca uaaccuccgc cgaacuacaa guauuccgcg      540

aacagaugca agacgcccuc ggaaacaaca gcucauucca ccacagaauc aacauuuacg      600

aaauaaucaa acccgccacc gcgaacagca aauuucccgu cacccgucuc cucgacaccc      660

gccucgucaa ccaaaacgcc ucccgcuggg aaucuuuuga cguaacaccc gcagucaugc      720

gcuggacagc acaaggccac gccaaccacg gauucgucgu agaaguagcc caccuagaag      780

aaaagcaagg aguauccaaa cgucacguac gaauaucacg cucccuacac caagacgaac      840

acuccugguc ccaaauccga ccccuacucg ucaccuucgg ccacgacgga aaaggacacc      900

cccuucacaa aagggaaaaa cgccaagcca aacacaaaca acgcaaacga cucaaauccu      960

caugcaaaag acacccccuc uacguugauu ucucagacgu cggcuggaac gacuggaucg     1020

uagccccacc cggcuaccac gccuucuacu gccacggcga augccccuuc ccccucgcag     1080

accaccuuaa uucaaccaac cacgcaaucg uccaaacccu cgucaacucc gucaacucaa     1140

aaauccccaa agccugcugc guccccaccg aacuaucagc caucuccaug uuauaccuag     1200

acgaaaacga aaaagugguc cucaaaaacu accaagacau ggucgucgaa gguugcggcu     1260

gccgauaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  6998
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt8)

<400>  6998
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auacccggca accgcaugcu cauggucguc cuccucugcc      120

aaguacuccu cggaggagcc ucacacgccu cacucauacc agaaacuggc aaaaaaaaag      180

ucgcugaaau ccaagggcac gccggcggcc gccgcuccgg ccaaucccac gaacuucuua      240

gagacuucga agccacccua cuccaaaugu ucggacuccg ccgccgcccc caacccucca      300

aaucugcagu uauacccgac uacaugcgcg accuauaccg ucuacaauca ggcgaagaag      360

aagaagaaca aauccauagu accggccucg aauaccccga acgccccgcc ucccgcgcaa      420

auacaguccg cucauuccau cacgaagaac accucgagaa cauccccgga acguccgaaa      480

acuccgccuu ccgauuccuc uucaaccuau cauccauccc cgaaaacgaa gucaucuccu      540

ccgccgaacu ccgccuuuuc cgcgaacaag ucgaccaagg ccccgacugg gaacgcggcu      600

uccaccgcau aaacaucuac gaaguaauga aaccacccgc cgaggucguc cccggacacc      660

uuaucacacg ccuccucgac acccgacuag uccaccacaa cgucacccga ugggaaaccu      720

ucgacguauc ccccgcaguc cuccgcugga cccgcgaaaa acaacccaac uacggacucg      780

ccauagaagu uacacaccuc caccaaaccc gaacacacca aggccaacac guccgaaucu      840

cccgcucccu cccacaaggc uccggcaacu gggcccaacu ccgcccccuc cucguaaccu      900

ucggacacga cggacgcgga cacgcccuca cccgacgccg ccgagccaaa cgcuccccca      960

aacaccacuc acaaagagcc aggaaaaaaa auaaaaauug ccgccgccac ucacucuacg     1020

uagacuucag cgacgucggc uggaacgacu ggauagucgc cccccccggc uaccaagcau     1080

ucuacugcca uggcgacugc cccuucccac ucgccgauca ccuaaacagc accaaccacg     1140

ccauagucca aacccuagua aacuccguca acuccagcau acccaaggca ugcugcguac     1200

ccacagaacu gagcgcaauc uccauguuau accucgacga auacgacaaa guaguacuca     1260

aaaacuacca agaaauggua guagaaggau gcggcugccg cuaaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  6999
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt8)

<400>  6999
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggauuag gucgccgagc acaguggcuc ugcugguggu      120

ggggacuccu cuguagcugc ugcggacccc ccccccuacg cccaccucuc cccgccgcug      180

ccgccgccgc cgccggcggc caacuacucg gagacggcgg aucacccggc cgaacugaac      240

aaccaccccc cucaccccaa uccucaagcg gguuccucua ccgucgccug aaaacccaag      300

aaaaacgcga aaugcaaaaa gaaauccuau ccguccucgg ccucccccac cgcccccgcc      360

cccuacacgg acugcaacaa ccccagccac cagcccuacg ucaacaagaa gaacagcagc      420

aacaacaaca auuaccaaga ggagaaccac ccccuggccg acugaaaucc gccccacuau      480

ucaugcucga ccuauacaac gcacucagcg cagacaauga cgaagacggc gcaucagaag      540

gagaaagaca acaaucaugg ccacacgaag cagccucaag cucccaacga agacaaccac      600

cacccggagc agcgcacccc cuaaaccgca aaucccuacu ggcccccgga uccggcagcg      660

gcggcgccuc cccacuaacc agcgcccaag acucugcauu ccuuaacgac gcagacaugg      720

ucaugucauu cguuaaccug gucgaauacg acaaagaauu cucgccccga caacgacauc      780

acaaggaauu caaauucaac cucagccaga uacccgaagg cgaaguaguc accgccgccg      840

aguuccgcau cuauaaagac ugcgucaugg gaucauucaa aaaccaaaca uuccuaaucu      900

ccaucuacca aguacuccaa gaacaccagc accgcgacag cgaccucuuc cuauuagaca      960

cccgcguagu cugggccuca gaagaaggcu ggcucgaauu cgacauaacu gccaccucaa     1020

aucuuugggu cgucacacca caacacaaca ugggccucca acucuccgua gucacccgug     1080

acggagucca cguacacccc cgagcugccg gccucgucgg acgagacggc cccuacgaca     1140

aacaacccuu cauggucgca uucuucaaag ucuccgaagu ccacguccga accacccgcu     1200

cagccuccuc ccgucgcagg caacaauccc gaaaccgauc cacacaaucc caagauguag     1260

ccagaguauc cuccgccucc gacuauaacu ccuccgaacu caaaacagca ugccgcaaac     1320

acgaacucua uguauccuuc caagaccuug gauggcaaga cuggaucauc gccccaaaag     1380

gauacgccgc caacuacugc gacggcgaau guucauuccc ucuaaacgcc cacaugaacg     1440

caaccaacca cgccaucgua caaacacuug uccaccucau gaaucccgag uacgucccca     1500

aacccugcug cgcacccacc aaacucaacg ccauaucagu cuuauacuuc gacgacaacu     1560

caaacguaau ccugaaaaaa uaccgcaaca uggucguucg cgcaugcggc ugccacuaag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  7000
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt8)

<400>  7000
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacguccguu cccugagagc cgccgccccc cacucguuug      120

ucgcccuaug ggcaccccua uuccuccuuc gaucagcacu ugcagacuuc ucccuugaca      180

acgaagucca cucguccuuc auccaccgcc gccucagauc acaagaacga cgagaaaugc      240

aacgcgaaau acuuagcauc cuaggccucc cccaccgucc ccgaccacau cuccaaggca      300

aacacaacuc agccccaaug uucaugcucg accucuacaa cgccauggcc gucgaagagg      360

gcggcggacc cggcggucaa ggcuucuccu acccauacaa agccgucuuc agcacucaag      420

gaccaccccu cgcuucccuu caagacuccc acuuccuaac cgacgcagau auggucaugu      480

ccuucgucaa ccuagucgag cacgacaaag aauucuucca cccccgcuac caccaccgag      540

aauuccgcuu cgaccucucc aaaauacccg aaggcgaggc cgucacagcu gccgaauucc      600

gcaucuacaa agacuacauc cgcgaacgcu ucgacaacga aaccuucagg aucucagucu      660

aucaaguccu acaagaacau cucggccgcg aauccgacuu auuccuccua gacucacgca      720

cccucugggc cucagaagaa ggauggcucg uauucgacau cacagccaca ucaaaccacu      780

gggucgucaa cccccgccac aaccucggcc ugcagcuauc aguagaaacc cucgacggac      840

aauccaucaa ccccaaacuc gccggucuca ucggccgaca cggcccacaa aacaaacagc      900

ccuucauggu cgccuucuuc aaagccaccg aaguccacuu ccgaagcauc cgcuccaccg      960

gauccaaaca acgcucccag aaucguucca aaaccccgaa aaaccaagag gcccuacgca     1020

uggccaacgu cgcagaaaac uccucaucag accaacgcca agccugcaaa aaacacgaac     1080

uauacgucuc cuuccgcgac cucggauggc aagacuggau caucgcacca gaaggcuacg     1140

ccgccuacua cugugaagga gaaugcgccu uuccucucaa cuccuacaug aacgccacca     1200

accacgcaau uguacaaacc cuaguucacu ucaucaaccc agaaacaguc ccaaaacccu     1260

gcugugcccc cacacaacua aacgcaauau ccguccucua cuucgacgau uccucgaacg     1320

uuauccucaa aaaauaccgc aacaugguag uccgagccug cggaugccac ugaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  7001
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt8)

<400>  7001
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagccucag ccgcccuccu cugccuccuc cucacagcag      120

ccgccuucuc cccccaaggc cucgcccaac cagucggcau caacaccucc acaaccugcu      180

gcuaccgcuu cauaaacaaa aaaauaccca aacaacgccu agaauccuac cgcagaacca      240

cauccucaca cugcccccgc gaagccguca ucuucaaaac caaacuagac aaagaaaucu      300

gcgccgaccc cacccaaaaa uggguccaag acuucaugaa acaccuagac aaaaaaacac      360

aaacccccaa acucuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  7002
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt8)

<400>  7002
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuguuaacgc uaaucauccu acuaccaguc guaagcaagu      120

ucucuuuugu cucccugagc gcgccccagc auugguccug cccagaaggc acccucgcag      180

gcaauggaaa cagcacaugc guaggcccgg cuccauuccu aaucuucagc cauggcaaca      240

gcaucuuuag aaucgacacc gagggcacca acuacgaaca acucguggua gaugccggag      300

ugagcguaau aauggacuuc cacuacaacg aaaaacgcau auauuggguc gaccuagaac      360

ggcagcuccu ccaaagggua uuucucaacg gaucccgaca ggagcgggug ugcaauaucg      420

agaaaaacgu cuccggaaug gcaaucaacu ggaucaacga agaagucauc uggagcaauc      480

agcaggaagg aaucauaaca gucacugaua ugaagggcaa uaacucccac auacuacucu      540

cagcacuaaa auaccccgcc aacguagcag uagauccugu ggaacgcuuc aucuucugga      600

gcucagaggu agccgguagc cucuacagag cggaucuuga cggagugggu gugaaagcac      660

uuuuagaaac aagcgagaaa auaaccgcag uaucccuuga cgugcucgac aaacgacuau      720

uuuggauuca guacaaucgg gaaggcucga acucccuaau augcucgugc gauuacgacg      780

gcggaagcgu acacauaagc aagcacccca cgcagcacaa ccucuuugca augucccugu      840

ucggugaccg aaucuucuac uccaccugga aaaugaagac cauauggauc gcgaacaaac      900

auacagggaa agauaugguc agaaucaacc uacacagcuc cuucgucccc cuaggagaac      960

uaaaggucgu acauccacuc gcccaaccca aagcggaaga cgacaccugg gaaccggaac     1020

aaaaauugug caaauuaaga aaggguaauu gcuccagcac ugucugcggg caagaccucc     1080

aaucacaccu cugcaugugc gcggaagggu augcccugag ccgggaccgc aaauauugcg     1140

aagacgucaa ugaaugcgcc uucuggaacc acggauguac gcuugguugc aaaaacacac     1200

ccgggagcua cuacuguacc ugccccguag gcuucguccu acugccggac ggcaagcggu     1260

gucaucagcu agucaguugc ccacgcaacg uuucagaaug cagccacgac ugcguccuaa     1320

cauccgaggg accacucugu uucugcccag aaggcucagu gcuagaaaga gacggaaaaa     1380

caugcagcgg gugcucaagc ccagauaaug gcgggugcuc gcaacuaugu gugccacuau     1440

ccccugucuc cugggaaugc gacugcuucc ccggauacga ucuccaacuc gacgaaaagu     1500

caugcgccgc caguggcccc caacccuuuc uucuauucgc caacagccaa gacauucgcc     1560

acaugcacuu cgacggaaca gacuacggaa cccucuuauc ucaacagaug ggcaugguuu     1620

acgccuuaga ucacgacccu guggaaaaca aaauauacuu cgcccacaca gcacuaaaau     1680

ggaucgaaag agcaaauaug gacggcucac aacgagaacg ccucauagaa gagggcguag     1740

acguacccga aggccuagcg guugacugga uaggcagaag guucuacugg acugaccgag     1800

gcaagucucu gauagggcgc ucggaccuga acggcaaacg cuccaaaauc auaacaaagg     1860

agaacaucuc ccaacccaga ggaaucgcag uucacccaau ggccaaacga cuguucugga     1920

ccgacacugg aaucaacccg cggaucgaau cuuccagucu acaggggcug gggcgucucg     1980

uuauugcauc gagcgaccug auauggccca gcggcauaac gauagacuuc cugacagaca     2040

aacuguacug gugcgacgca aaacaaagcg ugaucgaaau ggccaaucuc gacggaucaa     2100

aaagacgcag acucacacag aacgacgugg gccacccuuu cgcuguagcc guauucgaag     2160

acuacgucug guucucagac ugggccaugc ccagcguaau gcgaguuaac aaacgcaccg     2220

guaaagacag aguccgucuc caaggcucaa ugcuaaagcc uaguucccuu guaguaguac     2280

auccacuagc uaaacccggu gcagacccgu gccuauacca gaacggugga ugugaacaca     2340

uuugcaaaaa gcgauuggga accgccuggu gcagcuguag agaaggauuc augaaagcga     2400

gugacggaaa aacaugccuc gcacucgacg gccaccagcu ccuagccgga ggggaaguag     2460

aucucaaaaa ccaagugacg cccuuagaca uacuaagcaa aaccagagua ucggaggaca     2520

acaucacgga gagccaacac augcuuguag cugaaaucau gguaagcgac caagacgauu     2580

gcgcgccagu cggaugcagc auguacgcac ggugcaucuc cgaaggugaa gaugcuaccu     2640

gccagugccu aaaaggauuu gcgggagacg gcaaacuaug uagcgauauc gacgaaugcg     2700

aaaugggagu cccugucugu ccgccagcaa gcuccaaaug caucaacacc gagggagguu     2760

acguaugccg augcuccgag ggauaucaag gagacggcau acacugccuc gacauagacg     2820

aaugccaacu gggagagcac uccugcggcg aaaacgcaag cuguaccaac acagagggcg     2880

gcuacacaug caugugcgcc ggccgccuau cugaacccgg acucaucugc cccgacucga     2940

ccccuccucc gcaccuacgu gaggacgacc accauuacag cgugcgaaau uccgacucgg     3000

agugcccccu aucccacgac ggauacugcc uucaugacgg cgucugcaug uauaucgaag     3060

cccuagacaa auacgcgugu aauugcguug ucggcuacau cggggaacga ugccaguacc     3120

gcgaccuaaa auggugggaa cuaaggcacg ccgggcaugg ccagcagcag aaagucauag     3180

ucguggcagu cugcguagug gugcucguca ugcuacuccu acuaucacuc uggggagcgc     3240

acuacuaccg cacccaaaaa cuucuaagca aaaaucccaa aaacccauac gaggaaucaa     3300

gccgggaugu ucgaucgagg cgaccagcgg acacagaaga uggcaugagc ucgugcccgc     3360

agcccugguu cguggugauc aaggagcauc aagaccugaa aaacggggga caaccaguag     3420

ccggugaaga cggccaagca gccgacggua gcaugcagcc aaccucaugg agacaagaac     3480

cacaacucug cgguaugggc acagaacagg gcugcuggau ucccgucuca uccgacaagg     3540

gcagcugccc ccaaguaaug gagcgauccu uccacaugcc aagcuacgga acgcagaccc     3600

uagaaggcgg gguagaaaag ccgcauuccc ugcugucugc caacccccug uggcaacagc     3660

gcgcacucga cccaccucac cagauggaac ucacacaaug aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  7003
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt8)

<400>  7003
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggcc gacgaaugga aaugcucugc gccggccgug      120

uccccgcacu ucuccucugc cucggauucc accuacucca agccguccuc uccaccaccg      180

ucauccccuc augcaucccc ggagaauccu ccgacaacug caccgcccua guacaaacag      240

aagacaaccc ccgcgucgca caaguuucca ucaccaaaug cuccucagac augaauggcu      300

acugccucca cggacaaugc auauaccuag ucgacauguc ccaaaacuac ugccgcugug      360

aagucggaua cacaggcguc cgcugcgaac acuucuuccu caccguccac caaccccuau      420

ccaaagaaua cgucgcccuc accgucaucc ucauaauccu auuccucauc acaguugucg      480

gcuccaccua cuacuucugc cgcugguacc gcaauagaaa auccaaagaa ccaaaaaaag      540

aauacgaacg cguaaccuca ggcgaccccg aacucccaca agucuaagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  7004
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt8)

<400>  7004
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagaaggcg aaauaaccac auucaccgcc cucaccgaaa      120

aauucaaccu ccccccaggc aacuacaaaa aaccaaaacu ccuauacugc uccaacggcg      180

gacacuuccu ccgcauccuc cccgacggca cagucgacgg aaccagagac cgcucagacc      240

aacacaucca acuccaacuc uccgccgaau cagucggaga aguauacauc aaaagcaccg      300

aaaccggaca auaccuagcc auggacaccg acggcuuacu cuacggcuca caaaccccca      360

acgaagaaug ccucuuccuc gaacgccucg aagaaaacca cuacaacaca uacaucucca      420

aaaaacacgc agaaaaaaac ugguucgucg gccucaaaaa aaacggcucc ugcaaacgcg      480

gcccccgcac ccacuacggc caaaaagcca uacucuuccu cccccucccc gucucaucag      540

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  7005
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt8)

<400>  7005
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggggguag ggggagggga uguggaggau guaacgccga      120

ggccaggggg augccaaaua aguggaagag gggccagggg auguaacggg aucccgggag      180

cggcagcgug ggaggcagcg cugccgagaa ggagaccgag aaggcacccg agugugaacc      240

cgaggagcag ggcggcaggg agcccgagaa caagagggag aaggacagag gaaagaccau      300

cggggagcag guugggggau cgagggcgag gaagggcgcu gccgggaggg agauugggag      360

ggagagggag ggggagagcg ccagagaggg ugggaggaag ggggagagga agagggacgg      420

cggcaccgag ggcggcgccg gcggcaaggg gaagcagacc agggccggcg ggaacgaugg      480

cggcggggag cauaacgacg cuaccagcau ugcccgaaga cggaggaucg ggcgcauucc      540

cgccagggca uuuuaaagau ccgaagaggc uguacuguaa aaauggaggg uucuuucuga      600

gaauacaucc ggauggacgg guagauggag ugagagagaa gagugacccg cacauaaagu      660

ugcaacugca agcggaagag agaggaguag ugagcauaaa agggguaugu gccaacagau      720

aucuagcaau gaaggaagau ggaaggcuac uggcaagcaa guguguaacg gacgagugcu      780

uuuucuucga aaggcuagag aguaacaacu auaacacgua cagaagcagg aaauauacaa      840

guugguaugu ggcgcuaaag aggacgggac aauacaagcu ggggagcaag acagggccgg      900

ggcaaaaggc aauacuguuu uuaccaauga gugcgaagag uuaaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  7006
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt8)

<400>  7006
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uccuaaccug gauccuaccc acccuucucu      120

accgauccug cuuccacauc aucugccuag uaggaaccau cucacucgca ugcaacgaca      180

ugacacccga acaaauggcc accaacguca acugcuccuc cccagaacgc cacacacgca      240

gcuacgacua cauggaaggc ggagacaucc gcguccgccg ccucuucugc cgaacacaau      300

gguaccuccg caucgacaaa cgcggcaaag uaaaaggcac acaagaaaug aaaaacaacu      360

acaacaucau ggaaauacgc acaguagccg ucggaaucgu agcaaucaaa ggcgucgaau      420

ccgaauucua ccucgccaug aacaaagaag gcaaacuaua cgccaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa cucauccuag aaaaccacua caacacauac gcaucagcca      540

aauggaccca caacggaggc gaaauguucg ucgcccucaa ccaaaaaggc auccccguca      600

gaggcaaaaa aaccaaaaaa gaacaaaaaa cagcacacuu ccuccccaug gccaucaccu      660

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  7007
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt8)

<400>  7007
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuacucc ccuccgucgu ccuuaaacuc uuccucgccg      120

ccguacucuc cgcacucguc acaggcgaau cacucgaacg acuccgccga ggccucgccg      180

caggcaccuc aaaccccgac cccccaaccg uguccacaga ccaacuacua ccacucggcg      240

gaggacgcga ccgcaaaguc cgcgaccucc aagaagcaga ccuagaccuc cuccgaguca      300

cccucuccuc caaaccccaa gcccuagcca cccccaacaa agaagaacac ggcaagcgaa      360

aaaaaaaagg caaaggccua ggcaaaaaac gcgacccaug ccuacgcaaa uacaaagacu      420

ucugcaucca cggcgaaugc aaauacguaa aagaacuccg agccccauca ugcaucugcc      480

accccggcua ccacggagaa cgcugccacg gccuaucccu acccgucgaa aaccgccucu      540

acaccuacga ccacacaaca auccucgccg ucgucgcagu cguccucuca uccguaugcc      600

uccucgucau cgucggccua cucauguucc gcuaccaccg acgaggcggc uacgacgucg      660

aaaacgaaga aaaagucaaa cucggaauga caaacuccca cuaaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  7008
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt8)

<400>  7008
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggucacca agcuacuccc cgcucuccug cuacaacacg      120

uccugcucca ccuccuacuc cuccccauag ccauaccaua cgccgaagga caacgcaagc      180

gccguaauac aauacaugag uucaagaaaa gcgccaaaac cacccuuauc aaaaucgacc      240

ccgcccuaaa aaucaagacc aaaaagguga acaccgccga ccaaugcgcc aacagaugca      300

ccagaaacaa gggccucccc uucacaugca aagccuucgu auucgacaag gcccgcaaac      360

aaugccuaug guucccauuc aacuccaugu ccuccggcgu caagaaagag uucggccacg      420

aauuugaccu cuacgaaaau aaagacuaca uccgaaacug caucaucggc aaaggacgcu      480

cauacaaagg caccguaucc aucaccaaau caggcauaaa augccaaccc uggagcucaa      540

ugauccccca cgaacacuca uuucuaccau ccuccuaccg aggcaaagac cuccaggaaa      600

auuacugcag gaacccgcgc ggggaagaag gcggacccug gugcuuuacc uccaaccccg      660

aaguacggua cgaagucugc gacauacccc aaugcuccga aguagaaugc augacaugca      720

acggagaauc cuaucggggc cucauggauc acacagaauc agguaaaauc ugccagcgcu      780

gggaccacca gaccccucac cgccauaaau uccucccaga acgcuaccca gacaaagggu      840

ucgacgacaa cuacugcaga aacccugacg gccagccacg cccauggugu uacacacuag      900

acccccacac ccgaugggaa uacugcgcca ucaaaacaug ugcagacaau acaaugaaug      960

acaccgacgu cccacucgaa accaccgaau gcauccaagg gcagggagaa ggauaccgag     1020

gcacggucaa caccaucugg aacggcauac ccugccaacg gugggacagc caauauccgc     1080

acgaacacga caugacucca gaaaacuuca aaugcaaaga ccucagagag aacuacugca     1140

gaaaucccga cggauccgaa ucacccuggu gcuucaccac ggaccccaac auccgcguag     1200

gcuacugcuc acaaauacca aacugcgaua ugagccacgg ucaagacugc uaucgcggca     1260

acggcaaaaa cuacauggga aaccucucac agacccgcuc aggccuaacg uguagcaugu     1320

gggacaaaaa cauggaggac cuucaucggc acaucuucug ggaacccgac gcauccaaac     1380

uuaacgagaa cuacugccga aacccagacg acgacgccca cgggccaugg ugcuacacag     1440

gcaacccacu caucccgugg gacuauugcc ccauaagccg cugcgagggc gacacaaccc     1500

caacaaucgu gaaccuggac cacccuguca ucucgugcgc aaaaacaaaa cagcuucggg     1560

ucgucaacgg caucccaaca cgaacaaaca uaggguggau ggucucucua cgcuacagaa     1620

acaaacacau cugcggcggc ucacucauca aagaaagcug gguccucaca gcucgccaau     1680

gcuucccauc aagagaccuc aaagauuacg aagccuggcu aggcauacac gacguacaug     1740

gaaggggaga cgaaaaaugc aaacaaguac uuaacguaag ccaacucguc uauggcccag     1800

aaggaagcga ccucguccuc augaaacuag cacgcccagc cguccucgac gacuuuguaa     1860

gcaccauaga ccuccccaac uauggcugca ccaucccaga gaaaacgagu ugcucagucu     1920

acggcugggg auacacggga cugaucaauu acgacggacu acuccggguc gcacaccucu     1980

acaucauggg caacgaaaaa ugcucccaac accaccgcgg caaaguaacu cucaacgaaa     2040

gcgaaaucug cgccggagcc gagaaaaucg gcucaggccc augcgaaggc gacuacggcg     2100

gaccccuugu uugcgaacaa cacaaaauga ggaugguacu cggcguaaua guucccggca     2160

gggggugcgc caucccaaac cgacccggaa uauuugucag aguagcauac uacgcgaaau     2220

ggauucacaa aaucauacua accuacaaag ucccccaguc guaaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  7009
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt8)

<400>  7009
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaagccg ccgcaaucgg cauagaccuc gguacgacgu      120

acagcugcgu aggcgucuuc caacacggca agguggaaau aaucgcuaac gaccaaggca      180

acagaaccac accgucguac gucgcauuca ccgacaccga acgacucauc ggggacgcgg      240

ccaaaaacca agucgcacua aacccccaaa acacaguguu cgacgccaaa cgacucaucg      300

ggagaaaauu cggcgacccc guaguccagu ccgacaugaa acacuggccc uuccaaguaa      360

ucaacgacgg agauaaaccc aaaguacaag ucagcuacaa aggagagacc aaggccuucu      420

acccagagga aaucucaagc auggugcuga caaaaaugaa agaaaucgca gaagccuacc      480

uaggauaccc agucacgaac gccgucauca ccguccccgc auacuucaac gacagccaaa      540

gacaggccac caaagacgcc ggagucaucg caggacucaa uguccuacga auaauaaacg      600

agccaaccgc agccgccaua gcauacggac ucgaccgaac aggcaaagga gaacgcaacg      660

uccuaaucuu cgaccucggg ggcgggaccu ucgacgucuc cauccuaaca auagaugacg      720

gcaucuucga agugaaagcc accgccggcg acacacaccu cgggggagaa gacuucgaca      780

accgccucgu aaaccacuuc gucgaagaau uuaagcgaaa acacaagaaa gacaucagcc      840

aaaauaagcg cgcggugcga cgccugagaa ccgcaugcga gcgagccaaa cgaacgcucu      900

cauccucaac ccaagcguca cucgaaaucg acucacucuu cgagggaauc gacuucuaca      960

ccucaaucac gcgagcccgc uucgaagaau uaugcucaga ccucuuccga ucaacacuag     1020

aacccgucga aaaagcccuc agagaugcaa aacuggacaa agcacaaauc caugaccuug     1080

uccuaguagg aggcucaacc aggaucccca aaguacaaaa acugcuccaa gacuucuuca     1140

augggcgaga ccucaacaag uccauaaacc ccgacgaagc agucgcauac ggggcagcag     1200

uccaagcagc aauauuaaug ggcgacaagu cggaaaacgu ccaagaccuc cuacuacuag     1260

acgucgcgcc acuaagucua gggcucgaaa ccgcgggagg cgucaugacu gcccuaauca     1320

aacgcaacuc caccaucccc acaaaacaaa cccaaauauu caccacauac uccgacaacc     1380

aaccaggagu acugauacaa guauacgaag gcgaacgagc caugaccaaa gacaacaacc     1440

uacuaggacg cuucgaacuc agcggaaucc cacccgcccc cagaggagua ccccaaauag     1500

aagucacauu cgacaucgac gcaaacggca uccuaaacgu uacagcgacc gacaaaucca     1560

ccggaaaagc aaacaagaua acgaucacaa acgacaaagg cagacucucc aaagaggaga     1620

ucgagagaau gguccaagaa gcagagaaau acaaagcaga agacgaaguc caacgugaac     1680

gcgucagcgc caagaacgca cucgagucgu acgccuucaa caugaaaagc gccgucgagg     1740

acgaaggacu caaggggaaa aucucagaag ccgacaaaaa gaaaguacuc gacaaaugcc     1800

aagaaguaau cagcuggcua gaugccaaca cacucgccga aaaagacgag uucgaacaca     1860

aacgcaaaga auuagaacaa gucuguaacc ccaucaucuc cggacucuac caaggcgcag     1920

gcggaccagg ccccggcggc uuuggcgcac aaggccccaa aggcggcagc gguuccggcc     1980

ccacaauaga agaaguagac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7010
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt8)

<400>  7010
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaaagcgg cagcaaucgg aaucgacuua ggcaccaccu      120

acucgugcgu gggagucuuc caacacggca agguggaaau caucgcaaac gaccagggca      180

accgcaccac ccccagcuac guagccuuca cagacaccga acgccugaua ggagacgcag      240

cgaaaaacca ggucgcacuc aacccacaaa acacagucuu ugacgcaaaa cggcucauag      300

gaagaaaauu cggcgacccg gugguccaga gcgacaugaa acacuggccc uuccagguga      360

uuaacgacgg agacaagccg aaaguccaag ucucguacaa aggcgaaacc aaggcauucu      420

acccggaaga aaucuccucc augguccuaa ccaaaaugaa agaaauagcc gaagcauacc      480

ucggcuaccc cgucaccaac gcgguaauaa ccguccccgc auacuuuaac gacagucaac      540

gucaggccac caaagacgca ggggucauag cagggcucaa cguccuccga aucaucaacg      600

aacccaccgc agcagccaua gcauacgguc ucgaccgcac aggcaaaggc gaacgaaacg      660

uccuaaucuu cgaccuaggu gggggcaccu ucgacgucuc aauccuaaca auagacgacg      720

gcauauucga aguaaaggca accgcaggcg acacccaccu aggcggcgaa gacuucgaua      780

accggcucgu gaaccacuuc gucgaagagu ucaaacgcaa gcacaagaaa gacauaucgc      840

aaaacaaacg agcaguaagg cgacuccgaa ccgcgugcga acgagcaaaa agaacccuaa      900

gcucgagcac gcaggccagc cucgaaauag acucccucuu cgaagggauc gacuucuaca      960

caucaauaac acgagcacga uucgaagaac ucugcagcga ucuauuucgc ucaacccucg     1020

agccggucga aaaagcccuc cgcgacgcga aacuagacaa agcccagaua cacgaccuag     1080

uccuaguagg gggaucaacc aggauaccaa aaguacaaaa acuacuccaa gacuucuuca     1140

acgggcgcga ccugaacaaa ucuaucaacc cagacgaagc cgucgcguac ggcgccgcug     1200

uccaagccgc aauucugaug ggagacaaaa gugaaaacgu acaagaucuc cugcuacuag     1260

acguagcccc acuaucacug ggauuagaaa ccgcgggcgg agucaugacc gcccuaauaa     1320

aaagaaacuc aacaauccca acgaaacaaa cacaaaucuu caccaccuac agcgacaacc     1380

aacccggagu gcucauccaa guguacgaag gcgaacgcgc aaugacaaaa gacaacaacc     1440

uccuaggaag auucgaacua uccggcaucc caccagcccc acgcggaguc ccacagauag     1500

aagucacauu ugacauagac gcgaacggaa uacuaaacgu aacagcgacc gacaaaucga     1560

cgggcaaggc aaauaaaaua accaucacga augacaaagg gcgccuaagc aaggaagaga     1620

ucgaaagaau ggugcaggaa gccgaaaagu acaaggccga ggacgaaguc caaagagaac     1680

gggucagcgc caaaaacgca cuagaaucgu acgccuucaa caugaaaucc gcggucgaag     1740

acgaaggacu caaaggaaaa auaagcgaag cugacaaaaa gaaaguacuc gacaaaugcc     1800

aagaaguaau cuccuggcuc gacgcaaaca cauuagccga gaaggacgag uucgaacaca     1860

aacgaaaaga acuugaacaa guaugcaacc ccauuauuuc aggccuauac caaggagcag     1920

gagggcccgg gcccggaggc uucggcgcgc aaggcccaaa aggaggaucc ggaagcggac     1980

cgacaaucga agaagucgac ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7011
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt8)

<400>  7011
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaccgcca agggcaucgc caucgggaua gaccucggaa      120

caaccuacuc augcgucgga gucuuccaac acggcaaagu ggagauaauc gccaacgacc      180

aaggaaaccg aacgacaccc ucauacgugg cguucacaga uacagagcgg uuaaucggcg      240

acgcagccaa aaaccaaguc gccaugaacc cacaaaacac ggucuuugac gccaaaaggc      300

uaauuggcag aaaauucaac gaccccguag uccaggccga caugaaacuc uggcccuucc      360

aagucauaaa cgaaggcggc aaacccaaag uccuagucuc auacaaaggc gaaaacaaag      420

cauucuaccc ggaagaaauc ucgagcaugg ucuuaacaaa auuaaaagaa acggccgaag      480

cauuccuugg acaccccguc acgaacgcag uaaucacagu ccccgcauac uucaacgacu      540

cccaacgcca ggcgacaaaa gacgccgggg ucauagccgg ccuaaacguu cugaggauaa      600

ucaacgagcc gaccgccgca gccauagcgu acggacuuga caaaggagga caaggcgaac      660

gccacguacu caucuucgac cugggcggcg gcaccuuuga cgucuccauc uuaaccaucg      720

acgacggcau cuucgaagua aaagccacgg ccggagacac acaccuuggc ggagaagacu      780

ucgacaaccg gcucgucagu cacuuugucg aagaguucaa gcgcaaacac aagaaagaua      840

ucucgcaaaa caaaagagca guccgaagac uccgcaccgc cugcgaacgc gccaagagaa      900

cacucagcag cucaacacag gcaaaccugg aaaucgacuc acucuacgaa ggcauagacu      960

ucuacaccuc aauaacacga gcgcgcuucg aagaacuaug cgccgaccuc uucagaggga     1020

cccuggaacc ggucgaaaaa gcccuccgag acgccaaaau ggacaaagca aaaauccacg     1080

acauaguccu aguagguggg ucaacccgaa uccccaaagu gcaacgacuc cuccaagacu     1140

acuucaacgg gcgcgaccuc aauaaaucaa ucaaccccga cgaagcagua gcauacggcg     1200

cagcagucca agcagcgauc cuaauggggg acaagagcga aaaaguccag gaucuccucc     1260

uccuugacgu cgcaccucua ucucuaggac uagaaaccgc agggggugua augacagcac     1320

ucaucaaaag aaacucaaca auacccacca aacaaacaca aaucuucaca accuacuccg     1380

acaaccaacc aggaguacua auacaagucu acgaagggga acgcgccaug accaaagaca     1440

acaaccuccu gggccguuuc gaccuaaccg guaucccacc agcaccacgc ggaguaccgc     1500

aaauagaagu gacguucgac auagacgcaa acggaauccu caacgucacc gcgaccgaca     1560

aaucaaccgg caaagugaac aaaaucacca ucacaaacga caaagggcga uuaagcaaag     1620

aagaaaucga acgaaugguc cucgacgcag aaaaauauaa ggccgaagac gaaguccaac     1680

gagagaaaau agccgccaaa aacgcauuag aaucauacgc cuucaauaug aaaagcguag     1740

uaucagacga aggccuaaaa ggcaaaauca gcgagagcga caaaaacaag auacuagaca     1800

aaugcaacga acuccuaagc uggcucgagg uaaaccaacu cgcagaaaag gacgaguucg     1860

accacaaaag aaaagaacua gagcaaaugu guaacccaau cauaacaaaa uuauaccaag     1920

gaggcugcac ggggcccgcc ugcggaacag gcuauguccc aggaagaccc gccaccggcc     1980

ccacgauaga agaagucgac uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7012
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt8)

<400>  7012
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgcccggg gacccgcaau cggcaucgac cuaggaacca      120

cauacagcug cguaggcgug uuccaacacg gaaaagucga gauaaucgcc aacgaccaag      180

gaaaccgaac caccccauca uacguagcgu ucaccgacac cgaaagacuc aucggggaug      240

cagcgaagaa ccagguggcu augaacccca caaacacaau cuucgacgcc aaacgccuaa      300

uagggagaaa auucgaagac gcaacagucc aaucagacau gaaacacugg cccuucaggg      360

ucgucucaga aggaggaaaa cccaaaguac aagucgaaua caaaggcgaa acaaaaacgu      420

ucuucccaga agagaucuca uccauggucc ucacaaagau gaaggaaaua gccgaagccu      480

accuaggcgg caaaguccac agcgcaguca uaaccguacc agcauacuuc aacgacagcc      540

aacggcaagc cacaaaagac gcaggaacca ucaccggguu aaacguacua cgaauaauaa      600

acgaacccac agcagcagcc aucgcguacg gccucgacaa gaaaggcugc gccggaggcg      660

agaaaaacgu acucaucuuc gaccucggcg gaggcacauu cgacguaucg auacucacaa      720

uagaagacgg cauauucgaa gucaaaucaa ccgccggaga uacacaccuu ggaggggagg      780

acuucgacaa cagaauggug agccaccuag cagaggaguu caaacgaaaa cacaagaaag      840

acauaggacc caacaaaagg gccguacgca gacucagaac agcaugcgaa agagccaaac      900

gaacacuauc auccuccaca caggccagca uagaaauaga cucacuauac gaaggagucg      960

acuucuacac cagcaucaca cgcgccagau ucgaagaacu caacgccgac cuauuccgag     1020

gcacccucga gccggucgag aaagcgcucc gagacgcaaa acucgacaaa ggacaaauac     1080

aagaaauagu ccucgucgga ggcuccaccc gaaucccuaa aauacaaaaa cuacuccaag     1140

acuucuucaa cggaaaagaa cuaaacaaau caaucaaccc cgaugaagcc guugcauacg     1200

gcgccgcugu ccaagcagca auccuaauag gagauaaaag cgaaaacgua caagaccucc     1260

ugcuacuaga cgucacccca cucucacucg gaaucgagac cgccggcggu guaaugaccc     1320

cacucauaaa acgaaacacc accaucccca ccaaacaaac acagacguuc accaccuacu     1380

ccgacaacca aucauccgug cuagugcaag ucuacgaagg cgaaagagcc augaccaaag     1440

acaacaaucu ccucggcaaa uucgaccuga cgggcauacc cccagcccca cgaggcgucc     1500

cccaaaucga ggucaccuuc gacauagacg cgaacggcau ccucaacguc acugcugcag     1560

acaaaucgac aggaaaggaa aacaaaauca ccaucacaaa cgacaagggg cgccucagca     1620

aagacgacau cgaccgaaug guacaagaag cagaacgcua caagagcgaa gacgaagcca     1680

acagagaccg cgucgccgcc aaaaacgccc ucgaauccua cacauacaac auaaaacaaa     1740

ccgucgaaga cgaaaaacua cgcggaaaaa uaagcgagca agacaaaaac aaaauauuag     1800

acaaaugcca agaaguaauc aacuggcucg accgcaacca aauggccgaa aaagacgaau     1860

acgaacacaa acaaaaagaa cucgaacgag uaugcaaccc gauaaucagu aagcuguauc     1920

aaggaggccc aggaggcgga agcggcggcg gagguucggg cgcguccgga ggcccaacaa     1980

uagaagaagu cgacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7013
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt8)

<400>  7013
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgugguag gcauagaccu gggcuuccag agcuguuaug      120

ucgcaguagc ccgcgcaggc ggcauagaaa caaucgcaaa cgaguacagc gaccgcugca      180

caccggcaug caucucguuc ggacccaaaa accguagcau cggcgcggca gcgaaaagcc      240

aggucauaag caaugcgaaa aacacagucc agggauucaa acgcuuccac ggccgagcau      300

ucuccgaccc auucgucgaa gcagagaaaa gcaaccuggc auacgacauc guccaguuac      360

cgaccggccu aaccgggauc aaagucaccu acauggaaga ggaacgcaac uucaccacag      420

aacaagucac cgccaugcug cuaagcaaac ugaaagagac ugcagagucc guacucaaga      480

aaccaguggu ggacuguguc guaagcgugc cgugcuucua cacggacgcc gaacgacgua      540

gcgugaugga cgcaacacaa auagcgggac ugaacugucu ccgccuaaug aaugaaacga      600

cagcaguagc ccucgcuuac ggaauauaca aacaagaccu acccgcgcuc gaagagaaac      660

cccgcaacgu cgucuucgug gacaugggac acucggccua ccaagucucc gucugcgccu      720

ucaaccgggg caaacugaaa guccucgcca ccgcauucga caccacacuu ggaggccgaa      780

aauucgacga aguucucguc aaccacuucu gcgaagaguu cgggaagaaa uacaaacuug      840

acauaaaauc caaaauccga gcacugcucc gacucaguca agaaugcgaa aaacuaaaga      900

agcucauguc cgcgaacgcc agcgaccucc cccuauccau cgaaugcuuu augaacgacg      960

ucgacgucuc cggaaccaug aaccgaggga aauuccuaga aaugugcaac gacuuacuag     1020

cgagaguaga accaccccua cgaagcguac uagaacagac caaauuaaag aaagaagaua     1080

ucuacgcagu agaaauagug ggcggagcaa cccgcauacc cgccguaaaa gagaaaaucu     1140

caaaauucuu uggcaaagaa cucucgacaa cacuaaacgc cgacgaagca gugacccgcg     1200

ggugcgccuu gcaaugcgca auucucagcc ccgcuuucaa aguaagagaa uuuucaauaa     1260

cagacgucgu accauacccc auaucacucc gcuggaacuc cccagcagaa gaaggaagcu     1320

ccgacugcga agucuucucc aaaaaccacg cagcccccuu cucuaaaguc cucaccuucu     1380

accggaaaga acccuucacc cuagaagccu acuacucguc accacaggac cuaccauauc     1440

ccgaccccgc aaucgcgcaa uucuccgucc aaaaaguaac accccagagc gacgggagca     1500

gcagcaaagu uaaaguaaaa guacguguaa acguacacgg aaucuucuca gucuccucag     1560

ccucccucgu cgaaguccac aaaagcgaag aaaacgaaga accaauggaa accgaccaga     1620

augcaaaaga agaagagaaa augcaagucg accaagaaga accccacguc gaggagcaac     1680

aacaacaaac uccagccgaa aacaaggccg aaucagaaga aauggagacc ucacaagccg     1740

ggucaaaaga caagaaaaug gaucaaccgc cccaagcgaa gaaagcgaaa gucaaaacau     1800

ccacagucga ccuccccaua gagaaccaac ugcucuggca aaucgaccgc gagaugcuca     1860

accucuacau cgagaacgaa ggaaaaauga ucaugcagga caaacuagaa aaagaaagga     1920

acgacgccaa aaacgccgug gaagaguacg ucuaugaaau gcgcgacaaa uuaagcggag     1980

aguacgagaa auuugucucc gaagacgaca gaaacuccuu cacacuuaaa cucgaagaca     2040

ccgaaaacug gcuauacgaa gacggcgagg accagcccaa acaaguauac guggacaaac     2100

ucgcagagcu gaaaaaccua ggacaaccca ucaaaauccg auuucaagaa agcgaagaac     2160

gccccaagcu guucgaggaa cucggaaaac aaauccaaca auacaugaaa aucauaucau     2220

ccuucaaaaa caaagaggac caauacgacc accucgacgc cgcagauaug acgaaaguag     2280

aaaaguccac caacgaagcg auggaaugga ugaacaacaa acucaaccua caaaacaaac     2340

aaucgcucac aauggauccc gugguaaaga gcaaggagau cgaggcaaaa auuaaagaac     2400

ucacauccac augcagcccc auaaucucaa aacccaaacc aaaggucgaa ccgccaaaag     2460

aagaacagaa gaacgccgag caaaacggcc caguagacgg ccaaggcgac aacccaggcc     2520

cccaagcagc ggaacaggga accgacacgg ccguccccuc agauucggac aagaaacucc     2580

cagaaaugga caucgacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  7014
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt8)

<400>  7014
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaguggucg gcaucgaccu aggcuuccuc aacugcuaca      120

ucgccgucgc ccgcuccggc gggauugaaa caaucgcaaa cgaguacucg gacaggugca      180

cacccgcuug cauaucacug ggaucgcgga cgcgcgccau aggaaacgca gccaaaagcc      240

agaucguaac aaacgugcgc aacaccaucc auggcuuuaa aaagcuccac ggcaggagcu      300

ucgacgaccc caucguucaa accgagcgca ucagacuacc auacgaauua cagaaaaugc      360

ccaacggcag cgccggggua aaaguccgcu accucgaaga agaacgaccu uucgcgaucg      420

aacaaguuac cggaauguua cuagcaaaac ugaaggaaac cucagagaac gcccucaaga      480

aacccguggc agacugcgua auaucaaucc cuagcuucuu cacagacgca gaaagacguu      540

caguaauggc ggcagcccaa guagcagggc ucaacugccu ccgacuaaug aacgaaacaa      600

cagccguggc ccucgccuac ggcauauaca aacaagaccu gccgccacua gacgaaaagc      660

cccgcaacgu cguguucaua gacaugggac acagcgccua ccaaguccuc gucugcgccu      720

uuaacaaggg caaacucaaa guccucgcca cgacauucga ccccuaccug ggcggacgca      780

auuucgacga agcucucgua gacuacuucu gcgacgaguu caaaacaaaa uacaaaauca      840

acgucaagga aaacucaaga gcccugcucc gacuauauca agaaugcgag aaacuaaaga      900

aacucauguc cgcgaacgcc agcgaccucc cacuaaacau cgaauguuuu augaacgacc      960

uggacgucag cuccaaaaug aaccgcgccc aguucgaaca acucugcgcc agccuacuag     1020

cacgcgugga gccaccccuc aaagccguaa uggaacaagc gaaccuccag cgcgaggaca     1080

uaucaagcau cgagauagua ggcggcgcga cgcgcauccc cgccguaaaa gagcaaauca     1140

caaaauucuu ccucaaagac auuucaacaa cacuuaaugc agacgaagca guagccaggg     1200

gaugcgcucu acaaugcgcc auccucagcc cggcauucaa aguacgcgag uucuccauca     1260

cagaccuagu ccccuacuca aucacacuca gauggaaaac cucauucgaa gacgggagcg     1320

gagaaugcga aguauucugc aaaaaccacc cugccccauu cagcaaagug auaacguucc     1380

acaagaaaga acccuucgaa cuugaagcgu ucuacacaaa ccuucacgaa guccccuacc     1440

cugaugcgcg aaucgguuca uucacaauac agaacguauu cccccaaagc gacggcgacu     1500

cgagcaaagu aaaagucaaa guccgcguaa acauccacgg caucuucuca guagcaagug     1560

ccagcgugau cgaaaaacaa aaccucgaag gcgaccacag cgacgccccc auggagacag     1620

aaacaucguu caaaaacgaa aacaaagaca acauggacaa aaugcaggua gaccaagaag     1680

aaggccacca gaagugccac gccgaacaca cacccgaaga agaaaucgac cacaccggcg     1740

ccaaaacaaa aucggcaguc uccgacaaac aagaccggcu aaaccaaacc cucaagaaag     1800

gcaaaguaaa aucaaucgac cuacccauac aguccucacu cugccgccaa cugggccaag     1860

aucuccuaaa cucauacauc gaaaacgaag gaaaaaugau aaugcaagac aaacucgaaa     1920

aagaacggaa cgacgccaaa aacgcgguag aggaguacgu cuacgacuuu cgggaccgac     1980

ugggcacggu uuacgaaaaa uucaucacac ccgaagaccu aagcaagcua ucugcggucc     2040

uggaagauac cgagaacugg cucuacgaag acggcgaaga ccaaccaaaa caaguguacg     2100

uagacaagcu gcaggaacug aagaaauaug ggcaaccaau ccaaaugaaa uacauggaac     2160

acgaagaaag gcccaaagca cugaacgacc uaggcaagaa aauucaauua gucaugaaag     2220

ugaucgaagc guacagaaac aaagacgaaa gauacgacca ccucgacccu acagagaugg     2280

agaaaguaga gaagugcaua ucagacgcca uguccuggcu aaacagcaag augaacgccc     2340

aaaacaaacu cagccuuacg caagaccccg uggucaaagu cucagaaaua guugcgaaau     2400

caaaggagcu agauaacuuc ugcaacccca uaauauacaa accgaagccc aaagccgaag     2460

uccccgaaga caagcccaaa gccaacagug aacauaacgg gccgauggac ggacagucag     2520

gcacugagac caaaagcgac ucgacaaaag acagcaguca acacacaaag ucguccggag     2580

agauggaagu cgacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  7015
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt8)

<400>  7015
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacucagcc uagucgcagc caugcugcug cuccucagcg      120

cagcacgggc agaagaggaa gacaagaaag aagacguggg aacaguagua ggcauagacc      180

ucggaacgac auacagcugc guagggguau ucaaaaacgg acgagucgag aucauagcca      240

acgaccaggg caacagaaua accccaaguu acguagcguu cacacccgag ggugaacgac      300

ugaucggaga cgcagcgaaa aaccaacuca caagcaaccc cgaaaacaca guauucgacg      360

caaagcgacu aauaggccgc accuggaacg accccucggu ccagcaagac aucaaauucc      420

ugccauucaa agucgucgag aagaaaacaa aacccuacau acaaguagac auagggggcg      480

ggcagacgaa aacguucgcg ccagaagaaa uaagcgcaau gguacugacg aaaaugaaag      540

agaccgcaga agcguaccug ggcaagaaag ucacccacgc agucguaaca gugccagccu      600

acuucaauga cgcgcaacga caagcaacaa aggacgcagg aacaaucgcg ggacugaacg      660

ugaugcgaau cauaaaugaa cccaccgccg ccgcaauagc guacggacua gacaaacggg      720

aaggcgagaa aaacauccua gucuucgacc ugggcggagg uaccuucgac guaagucucc      780

ugacaaucga caacggcgua uucgaagucg uagcaacaaa cggggacaca caccugggag      840

gagaagacuu cgaccagcga guaauggagc acuucauaaa acuauacaag aagaaaaccg      900

gaaaagacgu aaggaaagac aacagagccg uacaaaaacu caggcgggag gucgaaaaag      960

ccaaacgcgc ccuauccagc caacaccaag cgcgcaucga aauagaauca uucuacgagg     1020

gggaagacuu cagcgaaacc cuaacacgcg caaaauucga agaacugaac auggaccuau     1080

uccgcagcac gaugaaacca guacaaaaag uccuagagga cagcgaccua aagaaaagcg     1140

acauagacga aauaguauua gugggcggcu cgaccaggau accaaaaaua caacaacugg     1200

uaaaagaguu cuucaacggc aaagaaccau cgcgagggau caacccagac gaagccgucg     1260

cauacggagc cgcaguucaa gcaggaguac ugagcggcga ccaagacaca ggagaccucg     1320

uacuacugga cgugugccca cucacccuag gcauagaaac aguaggcggg guaaugacaa     1380

aacucauacc aagaaacacg gucgugccca ccaagaaaag ccagauauuc agcacggcaa     1440

gcgacaacca acccaccgua acgaucaaag ucuaugaagg agaacgaccc cucacaaaag     1500

auaaccaccu acugggcacc uucgaucuaa caggcauacc accagcccca agagggguac     1560

cacaaauaga agugacauuu gaaaucgacg uaaacgggau ucuccgagug accgcggaag     1620

acaaaggaac cggaaacaaa aacaaaauaa cgauaaccaa cgaccaaaac agacucacac     1680

cggaagaaau cgaaagaaug gucaacgacg cagagaaauu ugccgaagag gacaagaaau     1740

ugaaagagcg aauagacacc agaaacgaac ucgaaagcua cgccuacuca cucaaaaacc     1800

agauagguga caaagaaaaa cuaggaggga aacuaagcag ugaagacaaa gaaaccaugg     1860

aaaaagccgu cgaagagaaa aucgaauggc uagaaucaca ccaagacgca gacauagaag     1920

acuucaaagc caaaaagaaa gaacuagaag aaauaguaca accaaucaua uccaaacuau     1980

acggaagcgc agggccccca cccacaggag aagaggacac agcggaaaaa gacgaacuau     2040

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  7016
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt8)

<400>  7016
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcacccc gggagcucgc agucggcauu gaucucggaa      120

caacauacuc cugcguagga guguuccagc aagggcgcgu ggaaauacuc gcaaacgacc      180

aaggcaaccg gaccacccca agcuacgugg ccuucaccga cacagagcgg cugguaggag      240

acgcagcaaa aagccaagcc gcgcugaauc cccacaacac agucuucgac gcaaaaaggc      300

uaauuggaag aaaauucgca gacacaacag uacaaagcga caugaaacau uggcccuucc      360

gagucgucuc agaagggggc aaacccaagg ucagagucug cuacagaggu gaagacaaaa      420

cauucuaccc cgaagagaua ucaagcaugg ugcucagcaa aaugaaagag acggccgagg      480

cauaccucgg gcaaccgguc aaacacgcgg uaauaacagu cccagcauac uucaacgaua      540

gccaacgcca agccacaaaa gacgccggag caaucgccgg gcucaacguc cuacgaauaa      600

ucaacgaacc aacagcggca gcaaucgcuu acgggcuaga cagaagaggc gcaggcgaac      660

ggaacguccu gauauucgac cuaggaggag gaacauucga cguaucagug cuaagcaucg      720

acgcaggagu auucgaaguc aaagccacgg caggagacac acaccugggc ggggaagacu      780

ucgacaacag gcuaguaaac cacuucaugg aagaguuccg gcgcaaacac gggaaagacc      840

uaucagggaa caaaagagcc cugcgaaggc ugagaacagc cugcgaacgc gcaaaaagga      900

cacuaagcag cuccacacaa gcaacacuag aaauagacuc ccucuucgaa ggagucgacu      960

ucuauaccuc gaucacgcgc gcacgauucg aagaacuaug cagcgaccuc uuccgaucga     1020

cccuggaacc gguagaaaaa gcccuaagag acgcgaagcu agacaaggcc caaauacacg     1080

acguaguccu cguaggagga ucgacacgca ucccaaaagu acaaaaacuc cuacaagacu     1140

ucuucaacgg gaaagaacuc aacaagucaa uaaaccccga cgaagcagug gccuacggug     1200

ccgcaguuca ggccgcaguc cugaugggcg acaagugcga aaagguucaa gaccuacuac     1260

uccuagacgu ggcaccccuc ucccucggac uagagacagc gggcggaguc augacuacac     1320

uaauccaaag aaacgcaacc aucccaacaa agcaaacaca aacauucaca accuacucag     1380

acaaccaacc aggcguauuc auccaagucu acgagggcga acgcgcaaug accaaagaua     1440

acaaccuacu gggccgauuc gagcucucag gcauaccccc agcaccccga ggagucccac     1500

aaauagaagu uacauucgac aucgacgcca acgggauauu gagcgugacc gcaacagacc     1560

gcucaaccgg aaaggcaaac aaaauaacaa uaacaaacga uaaaggacga cuaagcaaag     1620

aagaagugga gcgcauggua cacgaggcgg aacaauacaa ggccgaggac gaagcccaac     1680

gggacagagu agccgccaaa aacagccugg aagcgcacgu cuuccacguc aaaggaucac     1740

uacaggaaga aucccuccga gacaaaauac ccgaggaaga cagacgaaaa augcaagaca     1800

agugccgaga aguccuagcc uggcucgaac acaaccaacu ggccgaaaaa gaagaauacg     1860

aacaccaaaa gcgagaacua gagcaaauau gcagaccaau auucucgaga cuauacggcg     1920

ggccgggcgu accuggcgga ucgagcugcg gcacccaagc ccgacaaggc gacccaucaa     1980

ccgggccuau aaucgaggaa guggacuaag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  7017
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt8)

<400>  7017
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcaccac gcgaacucgc agucggaauc gaccuaggca      120

ccacauacuc augcgucggc guauuccaac aaggaagagu cgaaauccuc gccaacgacc      180

aaggaaaccg aaccacgcca agcuacgucg cauucacaga cacagaacgc cuggucggcg      240

acgcagccaa aagccaagcc gcacucaacc cacacaacac aguauucgac gcaaaacggc      300

ucauaggccg caaauucgcc gacaccaccg uccaaagcga caugaaacau uggccauucc      360

aagucguaag cgaaggcggc aaacccaaag uccgagucug cuacagaggc gaggacaaaa      420

cauucuaccc agaagaaauc uccagcaugg uacuaaguaa aaugaaagaa accgcagaag      480

cauaccuagg ccaacccgua aaacacgcag uaauaaccgu accaaccuac uucucaaaca      540

gccaacgcca agcaacaaaa gacgcaggag ccaucgccgg ccucaaaguc cucccaauaa      600

uaaacgaagc aaccgcagcc gcaaucgccu acggacucga ccgacgaggc gccggcaaac      660

gaaacguacu cauauucgac cucggcggcg gcaccuucga cguaagcgua cuaagcaucg      720

acgcaggagu cuucgaaguc aaagcaacgg ccggcgacac acaccuugga ggagaagacu      780

ucgacaacag guuagucaac cacuucaugg aagaguuccg ccgcaaacac ggaaaagacc      840

ucucaggaaa caaacgcgca cugcgacggc uacgaacagc gugcgaacgc gcaaaacgca      900

cccccuccag cagcacacaa gccacucucg aaaucgacuc acuguucgaa ggcgucgacu      960

ucuacaaauc cauaacacgc gcacgcuucg aagaacucug cagcgaccuc uuccgcagca     1020

cccucgaacc cguugaaaaa gcccuacgcg acgccaaacu agacaaagcc caaauccacg     1080

acuucguccu gggcggcggc cuccacucac acccccaagg agccgaagua gcagcaggac     1140

uccugcaacg ccaaggagca gaacaagaac accaacccua gggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  7018
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt8)

<400>  7018
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcaaaggac cagcaguagg gauagaccuc ggaaccacau      120

acuccugcgu agggguauuc cagcacggca aaguagaaau aauagcgaac gaccaaggca      180

accggaccac cccuuccuac guagccuuca ccgacacaga gcgccucauc ggagacgcgg      240

ccaaaaacca agucgcaaug aaccccacca acacaguauu cgacgcaaaa agacucauag      300

gcaggcgguu cgacgacgca gucguacaaa gcgacaugaa gcacuggccc uucauggucg      360

uaaacgacgc aggacgccca aaaguccaag uagaauacaa gggcgagaca aaauccuucu      420

acccagaaga ggucuccagc augguacuga ccaaaaugaa agagauagca gaagccuacc      480

ucggaaaaac uguaaccaac gcaguaguca cagucccagc cuacuucaau gacagccaac      540

gccaggccac caaagacgcc ggaaccaucg ccggacuuaa cguacuacgc aucaucaaug      600

agccaacggc ggccgcaauc gcguacgggc ucgacaaaaa gguaggagcc gaaagaaacg      660

uccugaucuu cgaccuagga ggaggaacau ucgacgucuc aauccucaca auagaagacg      720

gcauauucga aguaaagagc acggccggcg acacacaccu gggaggagaa gacuuugaca      780

acagaauggu aaaccacuuc auagcagagu ucaagcgcaa gcacaagaag gacaucagcg      840

aaaacaaaag agcaguacgc cgccuccgca ccgccuguga aagagcaaaa cgcacccuca      900

gcuccagcac ccaagcaagu auagaaauug acucacuaua cgaaggcauc gacuucuaca      960

ccagcaucac ccgagcaaga uucgaagaau uaaacgcaga ccucuucaga ggaacccugg     1020

acccagucga gaaagcacua cgagacgcaa aacuagacaa aagucaaaua cacgacauag     1080

uccuagucgg aggcagcaca cgaaucccga agauacagaa acuccuccaa gacuucuuca     1140

acggaaaaga acuaaacaaa agcauaaauc cagacgaagc agucgcauac ggcgcagcgg     1200

uccaagcggc cauacuuuca ggcgacaaaa gcgagaacgu acaagaccug cugcuccugg     1260

acgucacgcc gcucucacua ggcaucgaaa cagccggcgg cguaaugacc gugcucauaa     1320

aacgcaacac aaccauacca acaaaacaga cccagaccuu cacgacauac uccgacaacc     1380

agccaggcgu acucauacag gucuacgaag gagaacgcgc aaugacaaaa gacaacaacc     1440

uccuaggcaa auucgaacuc acagggauac ccccagcacc gcgcggaguc ccacaaauag     1500

aagucaccuu cgacaucgac gcaaacggaa uccuaaacgu auccgccgua gacaaaucaa     1560

ccggaaaaga aaacaaaaua acgaucacaa acgacaaagg ccgccuaagc aaggaggaca     1620

ucgagagaau gguccaggag gccgaaaaau acaaagccga agacgaaaaa caacgcgaca     1680

aaguaaguag caagaacagc cuggaaagcu acgcauucaa caugaaggcg acggucgaag     1740

acgaaaaacu gcagggaaaa auaaacgacg aagacaaaca gaaaauccua gacaaaugca     1800

acgaaaucau aaacuggcug gacaaaaauc aaaccgccga aaaagaagaa uuugaacacc     1860

aacaaaagga gcucgaaaaa gugugcaauc ccauaaucac caaacuauac caaucagcgg     1920

gaggaaugcc cggagggaug ccgggcgggu ucccaggagg gggagcaccc ccaagcggag     1980

gcgcaagcuc gggccccacg auagaggagg ucgacuaagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  7019
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt8)

<400>  7019
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaucagcca gccgcgcggc cgccgcaaga cuggugggag      120

cagccgcgag ccgcggacca acagcagcgc ggcaccaaga cagcuggaac ggacugucac      180

acgaagcauu ccgacucgug aguagaagag acuacgcgag cgaagccaua aaaggggccg      240

uagucggaau cgaccucgga acaacaaaua guugcguagc cgugauggag ggaaaacaag      300

ccaaaguacu agagaacgcg gagggagcga gaaccacacc aagcgucgua gccuucaccg      360

cagauggaga aaggcucgua ggcaugcccg caaaaagaca agcagugacg aacccaaaca      420

acaccuucua cgcgacaaag cgccucaucg gccgacgcua cgacgacccc gaggugcaaa      480

aagacaucaa aaacguacca uucaaaauag ugagagcaag caacggcgac gccugggucg      540

aagcccacgg caaacuauau agccccagcc agauaggggc cuucgucuug augaaaauga      600

aagagaccgc agaaaacuac cuaggacaca cagccaagaa cgcaguaaua accguaccug      660

cauacuucaa cgacagccag agacaagcca caaaggacgc cggccagaua agcggacuua      720

auguacuacg cguaauaaac gaaccgacag ccgccgcgcu cgcauacggc cuagacaaaa      780

gcgaggacaa aguaauagca guauacgacc uaggaggggg aacuuucgac aucucgauac      840

uagaaauaca aaagggaguu uucgagguca agucaacaaa cggggacacc uucuuaggcg      900

gagaagacuu cgaccaagcg cugcuacgcc acaucgugaa agaguucaaa agagaaacag      960

gggucgaccu cacgaaagac aacauggcac uccaaagagu cagagaagcg gcagaaaaag     1020

cgaaaugcga acuaagcagc agcguccaaa cagacauaaa ccuacccuac cuaacaaugg     1080

auagcucagg cccaaaacac cugaacauga agcucacgcg cgcgcaauuc gaggggauag     1140

ugacugaccu caucagaaga accauagcac caugccaaaa agcaaugcaa gaugccgaag     1200

uaagcaaaag cgacauaggg gaagucaucc uagucggagg aaugacgagg augccaaaag     1260

uacaacaaac aguacaagac cucuucggga gagccccguc caaggccgua aacccggacg     1320

aggcaguagc cauaggagcg gccauacaag gaggaguccu agccggggac guaacagacg     1380

ugcugcugcu cgacguaaca ccccugucuc ugggcauuga aacccuagga ggcguuuuca     1440

caaaacucau caacagaaac acgacgauac cgacuaagaa aucccaaguc uucuccacag     1500

ccgccgacgg ucaaacccaa guagaaauca aagucugcca aggagagagg gaaauggccg     1560

gggacaacaa auuacucggg caauucaccc ucaucggaau cccacccgcg ccccgaggcg     1620

ugccccagau agaggucaca uucgacaucg acgccaacgg aauaguacac guaagcgcca     1680

aagacaaagg aacaggccgg gaacaacaga uagucauaca gucaagcgga ggccucagca     1740

aggacgacau cgaaaacaug gucaaaaacg cagagaagua cgcagaagag gaccggagaa     1800

agaaagaacg cguggaagca guaaacaugg ccgaagggau aauacacgac accgagacaa     1860

aaauggagga guucaaagac cagcugcccg cggaugaaug uaauaaacua aaagaagaaa     1920

uaagcaaaau gagggaacua cucgcacgaa aggacucuga aacgggcgag aacauuagac     1980

aagcggcaag cagccuccaa caagcauccc ugaagcucuu ugaaauggca uacaagaaaa     2040

uggcgucgga aagggaaggg uccgggagcu caggcacggg agagcaaaag gaagaccaaa     2100

aggaggaaaa acaauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  7020
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt8)

<400>  7020
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcggacaaag aagccggagg aagcgacggc ccccgcgaaa      120

ccgccccaac auccgccuac agcucgcccg cccgcagccu aggagacacc ggaaucacac      180

cccucucucc cucccacauu gucaacgaca ccgacuccaa cguaucugaa caacaaucau      240

uccucguagu agucgcagua gacuucggca ccaccucguc cggauacgca uacucguuca      300

ccaaagaacc cgaauguauc cacguaauga gacgcuggga aggcggcgac cccggggucu      360

ccaaccagaa aaccccaacc accauacuac ucaccccaga aagaaaauuc cacuccuucg      420

gauacgccgc ccgcgacuuc uaccacgacc ucgaccccaa cgaagccaag caauggcucu      480

acuuggaaaa auucaaaaug aaacuccaua caaccggaga ccucaccaug gacaccgacc      540

ucacagcugc aaacggcaag aaagucaaag cacucgagau cuuugccuac gcgcugcaau      600

acuucaaaga acaagcccuc aaagaacucu ccgaccaagc agggucagag uucgaaaaua      660

gcgacguccg augggucauc accgucccag caauuuggaa acaacccgca aaacaauuca      720

ugcgccaagc cgccuaccaa gcuggccuag cuucaccaga aaacucagaa caacuaauca      780

uagcacucga accggaagca gcaagcaucu acugcagaaa acuacgccuc caccaaauga      840

ucgaacucag cucaaaagcc gccgugaacg gcuacuccgg auccgacacc guaggcgcgg      900

gcuucacaca agccaaagaa cacauccguc ggaaccgcca aucacgaaca uuccuagucg      960

aaaacgucau aggcgaaauc uggagcgaac uagaagaagg cgacaaauac gucguagucg     1020

acucaggcgg aggcacagug gaccucaccg uacaucaaau ccgccuacca gaaggccacc     1080

ucaaagaacu cuacaaagcu acaggcggac cauacggauc acugggcguc gacuacgagu     1140

ucgaaaaacu acuauacaag aucuucggcg aagacuuuau cgaacaauuc aaaaucaaaa     1200

gacccgccgc cuggguagac cucaugaucg ccuucgaauc cagaaagagg gcagccgcgc     1260

ccgaccgcac uaacccccug aacauaacac ucccauucag cuucaucgac uauuacaaga     1320

aauuccgcgg ccacucaguu gaacacgccc uccgcaaauc caacguagac uuuguaaaau     1380

ggucauccca aggcaugcuc cggauguccc ccgacgccau gaacgcccua uucaaaccaa     1440

ccauagauuc cauaaucgaa caccucagag accucuucca aaaacccgaa gucucaaccg     1500

uaaaauuccu uuuccuaguc gggggauucg ccgaagcgcc cuuacuacaa caagcggugc     1560

aagcugcauu cggcgaucaa ugccgaauaa uaauccccca agacguaggc cuaaccauac     1620

ugaaaggggc aguacucuuc ggccucgacc ccgcaguaau caaaguccga cgcuccccac     1680

uaaccuacgg cguaggcgua cucaacagau acguagaagg aaaacaucca ccagagaaac     1740

uccugguuaa agacggaacc agauggugca ccgacguauu cgacaaauuc aucagcgccg     1800

accaaucagu ugcacucggc gaauuaguua agcgaagcua cacccccgcg aaaccauccc     1860

aacucgucau cgucauaaau aucuacagcu cagaacacga caacgucucg uucaucaccg     1920

accccggggu caaaaagugc ggcacgcuca gacucgaccu caccggcacc agcgggacgg     1980

caguaccagc gcgacgcgag auacaaaccc ucaugcaauu cggcgacaca gagaucaaag     2040

ccaccgcgau ugacauagca acaucaaaau cugucaaagu cggaaucgac uucuuaaacu     2100

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  7021
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt8)

<400>  7021
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cucgccgucc ccgagauggg cuugcagggc cuauacauag      120

gcagcucacc cgaaagaagc ccagucccau ccccaccugg aucccccaga acccaagaau      180

ccugcggaau cgcuccccuc accccaucac aauccccaaa accggaaguc cgcgcacccc      240

aacaggccuc auucucaguu guugucgcca uagacuucgg cacaaccuca agcggauacg      300

ccuucagcuu cgccucagac cccgaagcca uacauaugau gcgcaaaugg gaggguggcg      360

accccggcgu cgcccaccag aaaacgccca cuugccuacu ccucacccca gaaggcgccu      420

uccacuccuu cggcuacacg gccagagacu acuaccacga ccucgacccc gaagaagcaa      480

gggacugguu guacuucgaa aaauuuaaaa ugaaaauuca uagcgccaca gaccuaaccc      540

uaaaaacgca auuagaagcu guaaacggca aaaccaugcc cgcccucgaa gucuucgccc      600

acgcacuccg cuucuuccga gaacacgcac uccaagaacu aagagagcaa ucacccagcc      660

uccccgagaa agacacagua cgcuggguac ugaccguacc cgccauaugg aagcaaccag      720

cgaaacaauu caugagagag gccgcauacc ucgcagggcu aguaucccgg gaaaacgcag      780

aacaacuccu cauagcauua gaaccagaag cagccucagu cuauugcaga aaacuccgcc      840

ugcaccaauu gcucgaccuc agcggccgcg ccccaggagg cggucgacuc ggcgaacgac      900

gaagcauaga cucaucauuc cgccaagcca gagaacagcu ccgccgaucc agacacucac      960

gaaccuuccu uguagaaucc ggcgucggag agcuuugggc cgaaaugcaa gccggggacc     1020

gauacgucgu agccgacugc ggcggcggaa ccgucgaccu aacaguacac caacuagaac     1080

aaccacaugg uacccucaaa gaacucuaca aagccuccgg cggucccuac ggagccguug     1140

gcguagaccu cgcauucgaa caacuacucu gcagaauauu cggagaagac uuuauagcua     1200

ccuuuaaaag acaacgaccc gcagccuggg ucgaccuaac uauagccuuc gaagcacgca     1260

aacgaacagc cggcccacac agagccggcg cacucaacau aagccuacca uucucguuca     1320

uagacuucua ccgcaagcaa agaggccaca acgucgaaac cgcccucaga cgaucauccg     1380

uaaacuucgu aaaaugguca agucaaggaa ugcugcgaau gucaugcgaa gcaaugaacg     1440

agcuauucca accgacagua agcggaauca uccaacacau cgaagcgcuc cuagcgcgcc     1500

cugaagucca aggcguaaaa cuucuauucu uaguuggagg auucgcagaa agcgccguac     1560

uucaacaugc aguccaagca gcacucggcg cacgcgggcu ccgagucguc gucccccacg     1620

acguuggccu aaccauacuc aaaggagccg uccucuucgg acaagcccca ggggucgucc     1680

gagugcgcag aucaccgcua acauacggcg uaggcgugcu caaucgcuuc guaccaggca     1740

gacacccgcc cgaaaaacuc cuaguccgag acggacggcg cuggugcacc gacgucuucg     1800

aaagauucgu cgcggcugaa caauccguag cccucggcga agagguacgu cgcagcuacu     1860

gcccagcccg acccggacag agacgaguuc ucaucaaccu cuacugcugu gcagcagaag     1920

acgcccgguu cauaacagac cccggcguaa gaaaaugcgg agcacucucc cuugaacuag     1980

aaccggcaga cugcggacaa gacaccgccg gcgccccacc cggaagacgc gaaaucagag     2040

ccgcaaugca auucggagac acagaaauca aagucacagc aguagacgua agcaccaaca     2100

gaagcgucag agcaagcaua gacuuccucu caaacuaggg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  7022
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt8)

<400>  7022
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgcgaaa ugaccauacu aggcuccgcc guauuaaccc      120

uccuccuugc aggcuaccua gcacaacaau accucccacu accaacccca aaagucauug      180

gcauugaccu cggaaccacg uacugcagcg ucggcgucuu cuucccugga accggcaaag      240

ucaaaguaau acccgacgaa aacggccaca ucuccauacc auccaugguu uccuucaccg      300

acaacgacgu guacgucgga uacgaauccg ucgaacucgc cgacagcaac ccacagaaca      360

ccaucuauga cgcaaaacga uucaucggaa aaauauucac agccgaagaa cucgaagccg      420

aaaucggacg cuauccauuc aaaguacuaa acaaaaacgg caugguagag uucuccguca      480

caagcaacga aaccaucacc gucagccccg aguacguagg aucuagacug cuucuaaaac      540

uaaaagaaau ggccgaagcc uaucugggca ugcccgucgc caacgcagua aucucggucc      600

ccgcagaguu cgaccuaaaa caacgaaacu caaccauaga agcggccaac cuagccggcc      660

ucaaaauacu aagagucaua aacgaaccca cugccgcggc uauggccuac ggucuccaca      720

aagccgacgu cuuccacguc cucgucaucg accucggcgg cggaaccuua gacgucagcc      780

uacucaacaa acaaggcggc auguuccuca cccgcgcaau gagcggcaac aacaaacucg      840

gaggccaaga cuucaaccaa cgccuacucc aauaccucua caaacagauc uaccaaaccu      900

acggcuuugu accaucccgc aaagaagaaa uacaccgacu ccgacaagcc gucgaaaugg      960

ucaaacucaa ccugacccua caccaaagcg cccagcuauc uguacuacua accgucgaag     1020

aacaagaccg caaagaaccc cacucaagcg acaccgaacu ccccaaggac aaacucagcu     1080

cugcggacga ccaccgcguc aacuccggcu ucggccgagg cuuaucagac aagaaauccg     1140

gagaaagcca aguccucuuc gaaaccgaga uaucccgcaa acuauucgac acacucaacg     1200

aagaccuauu ccagaaaauc uuaguaccca uacaacaagu ccucaaagaa ggccaccugg     1260

agaaaacaga aauagacgaa gucguccuag uaggcggcag cacacgcauc ccccgcauua     1320

gacaagucau ccaagaguuc uucggcaaag accccaacac cuccgucgac cccgaccuag     1380

ccgucgugac cgggguagca auccaagccg gcaucgacgg aggcuccugg ccacuacagg     1440

ucucggcacu ugaaaucccg aacaaacacc uccagaaaac caacuucaau uaaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  7023
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt8)

<400>  7023
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagcaaucg gcguccaccu cggaugcaca ucagccugcg      120

ucgccgucua caaagacggg cgcgccggcg ucgucgcaaa cgacgcgggc gaccgcguca      180

caccagccgu cgucgcauac uccgaaaacg aagaaauagu aggccuagcc gccaagcaau      240

cccgcauacg caacaucagc aacacaguca ugaaaguaaa acaaauauua ggccgcuccu      300

ccuccgaccc acaggcccaa aaauacaucg cagaaucaaa augccucgua aucgagaaaa      360

acggcaaacu acgcuacgag aucgacacug gcgaagaaac caaguucgua aacccagaag      420

acgucgcccg ccuaaucuuc ucaaaaauga aagaaacggc ccacucaguc cucggcuccg      480

acgccaacga ugucgucaua accguaccau ucgacuucgg cgaaaaacaa aagaacgcac      540

uaggcgaagc cgcccgcgca gcgggauuca acguccuacg ccucauacac gaaccauccg      600

cggcccucuu agcuuacgga aucggacaag acucccccac cggcaaguca aacauccuag      660

uauucaaacu aggaggaacc ucacuaucac ucucagucau ggagguaaac ucaggcaucu      720

accgcguccu cagcaccaac acagacgaca acaucggagg agcccacuuc accgaaacac      780

ucgcccagua ccucgccucc gaguuccagc gaucguucaa acaugacgua cgaggaaacg      840

cacgcgcaau gaugaagcuc acgaacagcg cagaagucgc aaagcacucc cuaagcacac      900

uaggcagcgc aaacugcuuc cuggacucau uauacgaagg acaggacuuc gacugcaacg      960

uaagccgcgc cagauucgaa cuccucugcu caccccucuu caacaaaugc aucgaagcca     1020

uacgcggacu acuagaccaa aacggguuca ccgccgacga caucaacaaa gucguucucu     1080

gcggcggauc cagccgcauc cccaaacugc aacaacucau caaggaccua uuccccgccg     1140

ucgagcugcu aaacuccaua ccacccgacg aaguuauacc cauuggagca gcaauagagg     1200

ccggcauccu caucggcaaa gagaaccucc ucgucgaaga cucccugaug aucgagugcu     1260

ccgccagaga cauacucguc aaaggcgucg acgaaucagg agcaucacgc uucacagucc     1320

uauuccccuc uggaacaccc cuuccagcac gacgacaaca cacccuacaa gcaccaggca     1380

gcauuuccuc cgucugccua gaacucuacg aauccgaugg caaaaacucg gccaaagaag     1440

aaaccaaguu cgcacaaguc guacuccaag accucgacaa gaaagaaaac ggacuccgcg     1500

acauccuggc cgugcucacc augaagcgag auggaucacu acacgugacc ugcaccgacc     1560

aggaaaccgg caaaugcgaa gccaucagca ucgaaaucgc auccuaagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  7024
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt8)

<400>  7024
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgucgucg gacuggacgu gggaagccaa agcugcuaca      120

uagcagucgc ccgggcaggg ggcaucgaaa caaucgccaa ugaguucagc gacagaugca      180

cuccaagcgu caucuccuuc ggauccaaaa acagaacaau aggagucgcc gccaaaaacc      240

aacagauaac ccacgcaaac aacaccgucu caaacuucaa acgguuccac ggcagagcau      300

ucaacgaccc cuucauacaa aaagaaaaag aaaaccuauc auacgaccuc gucccacuca      360

aaaacggagg agucgguauc aaagucaugu acaugggcga agaacaccuu uucucaguag      420

agcaaauaac agcaaugcua cuaaccaaac ucaaagagac agcagaaaac ucgcugaaga      480

aaccagucac agauugcguc auaagcgucc cgagcuucuu caccgacgcc gaacgacgcu      540

caguacuaga cgcagcccaa aucgucggcc ugaacugucu cagacuaaug aacgauauga      600

cggcagucgc ccuaaacuac ggcauauaca aacaggaccu cccaucacug gaugaaaaac      660

cacguaucgu ggucuucguc gacaugggcc acucagcauu ccaagucucc gcaugcgccu      720

ucaacaaagg caaacucaaa guacuaggca cagccuucga cccauuccuu gggggcaaaa      780

acuucgacga aaaacugguc gagcacuuuu gcgcagaguu caaaaccaaa uacaaacucg      840

acgccaaaag caaaauccga gcacuucuac gauuauacca agaaugcgaa aaacucaaga      900

aacucaugag cagcaacucg acagaccucc ccuugaacau cgaaugcuuc augaaugaca      960

aggacguguc agggaagaug aaccggucac aguucgaaga acugugcgcc gaacuccugc     1020

agaaaaucga agucccacug uacucccuac ucgaacaaac ccaccugaaa gucgaagacg     1080

ucucagcagu agaaaucgug ggaggggcaa cccgaauacc ugccgucaaa gaacguaucg     1140

cgaaauucuu cggaaaagac aucaguacaa cgcucaacgc cgacgaagca gucgccagag     1200

ggugcgcacu ccaaugcgcg auccuauccc ccgcguucaa aguacgcgag uucuccguga     1260

cugacgccgu cccauuccca aucucacuaa ucuggaacca cgacucagaa gacacggaag     1320

gaguccacga agucuucagc cgcaaccacg cugcccccuu cucuaaagua uuaaccuucc     1380

uccgccgagg uccauucgaa cucgaagcgu ucuacucaga cccacaaggg guacccuacc     1440

cggaggcgaa aaucggccgc uuuguaguac aaaacgucuc agcccagaaa gacggcgaaa     1500

aaucccgggu caaagucaaa guccgcguca acacccacgg cauauucacc aucucaacug     1560

ccagcauggu cgagaaagua ccaacagagg agaacgaaau gucaagcgaa gccgacaugg     1620

aaugccuaaa ucaaagaccg ccagaaaacc cugacaccga caaaaacgua caacaagaca     1680

auuccgaagc agggacccag ccacaagucc agacagacgc acaacagacc agccaaucac     1740

ccccaucccc agagcucacg agcgaagaaa acaaaauacc agacgcagac aaggcaaacg     1800

aaaagaaagu cgaccagccg ccagaagcga aaaagccgaa aaucaaagua gucaacgucg     1860

aacuccccau agaagcaaac cucguauggc agcucgggaa agaccuccua aacauguaca     1920

ucgagacaga aggcaaaaug auaaugcaag acaaacuaga aaaagaaaga aacgacgcua     1980

aaaacgcagu agaagaguac gucuacgagu uccgcgacaa acucuguggg cccuacgaaa     2040

aauucaucug cgaacaagac caccaaaacu uccuaagacu ccuaaccgaa acggaagacu     2100

ggcucuacga agaaggcgag gaccaagcaa aacaagccua cgucgauaaa cucgaggagc     2160

uaaugaaaau cggcacgccc gucaaagucc gcuuccaaga agcagaagaa cgaccgaaga     2220

uguucgaaga acugggccag cgcuugcaac acuacgcgaa aauagcggcc gacuuccgca     2280

acaaagacga aaaauauaac cacauagacg aaucagagau gaaaaaggua gagaaaagcg     2340

uaaacgaagu aauggaaugg augaacaacg ucaugaacgc ccaagccaag aaaucacuag     2400

accaagaccc cguugucaga gcccaagaaa uaaaaaccaa aauuaaagaa cucaacaaca     2460

caugcgagcc agucgucacc caaccgaaac caaaaauaga aucuccaaaa cucgaaagaa     2520

ccccaaacgg cccuaacauc gauaagaaag aagaggaucu cgaagacaaa aacaacuucg     2580

gggcagaacc cccgcaccaa aacggcgaau gcuaccccaa cgagaaaaac ucugugaaca     2640

uggaccuaga uuaaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  7025
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt8)

<400>  7025
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaaag uccgacgaca acgaccgcgc cgacgaguau      120

guugggcgcu cgucgccgua cugcucgccg accuacuggc ccuaagugac acccucgcag      180

ugaugagugu agaccuaggc uccgaaucca ugaaggucgc gauagucaaa ccaggagugc      240

cgauggaaau aguccucaac aaggaaucca ggcgaaaaac cccaguaaua guaacccuca      300

aagaaaacga gcgguucuuu ggagacucag cagcaagcau ggcaaucaag aauccaaaag      360

ccacccuacg auacuuccaa caccuacuag gaaagcaggc agacaaccca cacgucgcac      420

uauaccaggc cagguucccg gaacacgagc ugaccuucga cccccaaagg caaacgguac      480

acuuccaaau cagcagccaa cuacaauuca gcccagaaga aguccucgga augguccuaa      540

acuacagcag aagccucgca gaggauuucg ccgaacagcc aauaaaagac gccguaauaa      600

cagucccagu auucuucaac caagccgagc gacgagccgu ccuacaggca gcacgcaugg      660

ccgggcucaa gguacuccag cuaauaaacg acaacacggc aacggcccua uccuacggag      720

ucuuucggag aaaagacaua aacacaaccg cacaaaacau aauguucuac gacaugggcu      780

caggcucgac agucugcaca auagucacau accagauggu caaaacaaag gaagccggga      840

ugcaaccgca acugcaaaua cgaggagucg gauucgaccg aacacuggga ggacuagaaa      900

uggaacuacg acuccgagag aggcuggccg gccuauucaa cgaacaaaga aaaggccaac      960

gcgcaaaaga cguaagggaa aacccacgag caauggcuaa acuacuccga gaagccaacc     1020

gacugaaaac aguacuaagc gcaaacgcag accacauggc gcaaauugaa gggcuaaugg     1080

acgacguaga cuucaaagca aaagucaccc gcguggaguu cgaggaacuc ugcgcagacc     1140

uguuugaacg cguccccggc cccguacaac aagcacugca aagcgcagaa augagccuag     1200

acgagauaga acaaguaauc cuaguaggcg gcgccacacg aguacccaga guucaagagg     1260

uacuacugaa agcugucggg aaagaggaac uaggcaaaaa caucaacgcc gacgaggccg     1320

cagcaauggg agccguauau caagcagcag cauuaaguaa agcauucaag guaaagccgu     1380

uuguaguacg ggacgccguc guauacccaa uuuuagucga guucacgcgg gaagucgaag     1440

aggaacccgg aauacacuca cugaaacaca acaaacgcgu ccuauucuca cgaauggguc     1500

ccuacccaca aagaaaagua auaaccuuca accgauacag ccacgacuuc aauuuccaca     1560

ucaacuacgg cgaccuugga uuccuagggc ccgaagaccu gagagucuuc ggaagccaga     1620

accucaccac agucaaacug aaaggagugg gggacagcuu caagaaauac ccagacuaug     1680

aaucaaaagg aauaaaggca cacuucaacc ucgaugaaag cggaguacug agccuggaca     1740

ggguagaaag cguuuucgag acacuggugg aagacagugc cgaagaagag agcacacuaa     1800

caaaacuggg caacacaauc aguagccucu ucgggggcgg aacaacgcca gacgcaaaag     1860

aaaacgggac cgacaccgua caagaagaag aagaaagccc agccgaagga agcaaggacg     1920

agccaggaga gcagguagag cucaaagaag aagcagaggc gcccguagaa gacggcucuc     1980

agccaccucc gcccgaaccc aaaggagacg caacaccaga gggagagaag gcgaccgaaa     2040

aagaaaacgg cgacaaaagc gaggcgcaaa aaccgucgga gaaagccgag gcgggaccag     2100

aaggaguagc cccagcaccc gaaggcgaaa agaaacaaaa accagcgaga aaaagaagga     2160

ugguggagga aaucggcgug gaacugguag ugcuagauuu acccgaccuc ccagaagaca     2220

aacucgcgca gucgguacag aaauuacaag accugacacu aagagaucuu gaaaaacaag     2280

aacgagagaa ggcggcaaac agucuggaag cguucaucuu cgagacgcag gacaaacuau     2340

accagccgga guaccaagag guaucaaccg aagaacaaag agaggaaauc uccggcaagc     2400

uaucggcggc cucaacaugg cucgaggaug aagggguagg cgccaccaca gugaugcuaa     2460

aagaaaagcu agcugaacua agaaaacuau gccaaggucu auuuuuccga gucgaggaaa     2520

ggaagaaaug gccagaaaga cuaucggccc ucgacaaccu acuaaaccac uccagcaugu     2580

uucuaaaagg cgcgagacua auaccagaga uggaccaaau cuucacggaa gucgaaauga     2640

ccacacuaga aaaagugaua aacgagacgu gggcauggaa aaaugccaca cucgcagaac     2700

aagccaaacu acccgcaacg gaaaagcccg uccuacucag caaagacauc gaagcaaaaa     2760

ugauggcguu agaccgcgaa guacaguacc uacuaaacaa agcgaaauuc accaaaccac     2820

gaccccgccc caaagacaaa aacggcacac gggcagagcc accacugaac gcaagcgccu     2880

cagaccaagg ggaaaagguc auacccccgg ccggacaaac cgaagacgcg gaaccaauaa     2940

gcgagcccga aaagguggag acgggaagcg aacccggcga cacagagcca cuggaacuag     3000

gaggcccggg cgcagaacca gagcaaaagg aacaaagcac agggcaaaag aggccacuca     3060

aaaacgauga acuauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  7026
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt8)

<400>  7026
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaagaaa cgcaaacgca agaccaacca auggaagagg      120

aggaaguaga aacguucgcc uuccaggcag agaucgccca acuaaugagc cugauaauaa      180

acacauucua cucgaacaaa gagauauucc ucagagagcu cauaagcaac agcucggacg      240

cacuggacaa aauacgauac gaaucccuaa ccgacccgag caaacucgac uccggcaaag      300

aacuccacau caaccuaaua ccaaauaaac aggaccggac acucaccauc gucgacacag      360

ggauaggaau gacaaaagcg gaccugauca acaaccuagg aacgauugca aaaagcggaa      420

caaaagcguu cauggaagcc cuccaagcag gcgccgauau auccaugaua ggacaauucg      480

gcgugggguu cuacucagca uacuuagucg cggaaaaagu cacgguaaua acgaaacaca      540

acgacgacga acaguacgcg ugggagagcu ccgcaggcgg cagcuucaca guuaggacag      600

acaccggaga gcccaugggg cgagggacca aggucauccu ucaccucaaa gaagaccaaa      660

cggaauaccu cgaagaaagg cgcauaaagg aaaucgugaa gaaacacucc caauucauag      720

gauacccuau cacacuauuc guagaaaaag aacgcgacaa agagguaagc gacgacgaag      780

cggaagagaa ggaagacaag gaagaggaaa aagagaagga agagaaagaa agcgaagaca      840

agcccgaaau agaagacgua ggcucggacg aggaagaaga aaagaaagac ggcgacaaaa      900

agaagaaaaa gaaaauaaaa gaaaaauaca uugaccagga ggaacucaac aaaacgaaac      960

cgauauggac caggaacccg gacgacauca caaacgaaga auacggggag uucuacaaau     1020

cgcucacaaa cgacugggaa gaccaccuag cggucaaaca cuucagugug gagggacaac     1080

uagaguucag agcacuccug uucgucccaa ggcgagcccc auucgaccua uucgaaaacc     1140

gcaaaaagaa aaacaacaua aaacucuacg ucagaagagu cuuuauaaug gacaacugcg     1200

aggaacuaau ccccgaauac cuaaauuuca uccgaggggu cguggacucu gaagaccucc     1260

cacuaaacau cucaagagaa augcugcagc aaaguaagau ccuaaaagug auccgcaaaa     1320

accuaguaaa gaaaugccug gaacuguuca cggaacuggc ggaggauaaa gaaaacuaca     1380

aaaaguucua cgaacaauuc uccaagaaca uuaaacuggg gauccacgaa gacucccaaa     1440

acagaaagaa acugagcgaa cuccugcgau acuacaccag cgcguccgga gacgagaugg     1500

ucagccuaaa ggacuacugc accagaauga aagaaaacca aaaacacauc uacuauauaa     1560

caggggaaac caaggaccaa gucgcaaaca gcgccuuugu agagcgccug agaaaacacg     1620

gacucgaagu cauauacaug auagaaccaa ucgacgaaua cugcguacag cagcugaagg     1680

aguucgaagg aaaaacgcua guaucgguaa cgaaagaggg acuagagcua cccgaagacg     1740

aggaagagaa aaagaaacaa gaagaaaaga aaaccaaauu cgagaaccuc ugcaaaauaa     1800

ugaaagacau ccuagaaaag aaaguagaaa aagucguagu gucaaaccgc cucgucacga     1860

gcccauguug cauagucacg ucaaccuacg gauggacagc caacauggag aggauaauga     1920

aagcccaagc ccuacgagac aacucaacaa ugggauacau ggccgccaag aaacaccuag     1980

aaauaaaccc cgaccauucg auaauagaga cucuccgaca aaaagccgag gccgacaaga     2040

acgacaagag cguaaaagac cugguaaucc uccucuacga aacggcccuc cuaucaagcg     2100

gguucagccu agaagaccca caaacccacg ccaaccgcau cuacagaaug auaaaacuag     2160

gacucggaau cgacgaagac gacccgaccg cggacgacac cucagcagcg guaacagagg     2220

aaaugccccc acuagaaggg gacgacgaca cgagcagaau ggaggaagua gacuaaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  7027
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt8)

<400>  7027
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccucaa aacuagacuc cggcaaagga cuccacauca      120

accucguccc caacaaacaa aaccaaacac ucaccauagu agacacacgc aucggcauga      180

ccaaaacaga ccucaucaac aaccucggca ccgucaccaa auccggaaca aaagccuuca      240

uggaagcacu ccaagccgac gcagacaucu ccaugaucgg acacuucggc gucggcuucu      300

acucagcaua ccucgucgcc aaaaaaguca ccguaaucuc aaaacacaac aacgacgaac      360

aauacaccug ggaauccucc gcaggcggcu ccuucaccgu acgaacagac gaauaaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  7028
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt8)

<400>  7028
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaagagg uacaccaugg ugaagaggaa gucgagaccu      120

ucgccuucca agccgaaaua gcacaauuaa ugagccugau aaucaacacc uucuacucga      180

acaaagaaau cuuccugcgc gaacucaucu cgaacgcaag cgacgcccua gacaagauaa      240

gauacgaauc acugacagac cccagcaagc uagacucagg gaaggagcuc aaaaucgaca      300

ucauuccaaa cccccaagaa cggacacuaa cccuggugga cacagggauc gggaugacca      360

aggccgaccu gauaaacaac cucgggacaa ucgccaaaag cggcaccaaa gcguuuaugg      420

aggcccuaca agccggagcc gacaucagca ugaucgggca auucggcguc ggauucuaca      480

gcgccuaucu aguagcggaa aaaguaguag ugaucacaaa acacaacgac gacgaacaau      540

acgccuggga aagcagugca ggaggcagcu ucacggugcg agccgaucac ggagaaccca      600

uaggacgggg caccaaggug auacugcacc ucaaagaaga ccaaaccgaa uaccuggaag      660

aacgacgagu aaaggagguc guaaagaagc acagccaauu cauaggcuac ccaauaaccu      720

uguaccuaga gaaagaacgg gaaaaagaga uaagugacga cgaagcugaa gaagaaaaag      780

gcgaaaaaga agaagaagac aaagacgacg aagaaaagcc caaaaucgag gacguaggca      840

gcgacgaaga agacgacagc ggaaaagaca agaaaaagaa aacaaagaaa auaaaagaga      900

aguacaucga ccaagaagaa cucaacaaaa cgaagcccau auggacaaga aauccagacg      960

auaucacgca agaagaauac ggagaguucu auaagagucu aaccaacgac ugggaagacc     1020

accuagcggu caaacacuuc agcgucgaag gacagcuaga guuccgagcc cugcuauuca     1080

ucccccgaag ggcacccuuc gaccuauuug aaaacaaaaa gaagaaaaac aacauuaaac     1140

ucuacguacg ccgcgucuuc auaauggaca gcugcgacga acuaauacca gaauaccuga     1200

acuucauccg cggagucguc gacagcgaag accuaccacu gaacauauca cgagaaaugc     1260

ugcaacaaag caaaauccuc aaagucauac gcaaaaacau cguaaagaaa ugccuugaac     1320

uauuuucgga acuggcagaa gacaaagaaa auuacaagaa auucuacgaa gccuucagca     1380

aaaaccucaa acugggaauc cacgaagacu ccacaaaccg aagaagacua agcgaacucc     1440

uaagauacca caccagucaa agcggcgacg aaaugacaag ccucucagaa uacguguccc     1500

gaaugaaaga aacccagaaa agcaucuacu acaucacggg cgaaagcaaa gaacaaguag     1560

caaacagugc uuucguagaa cgggugagaa agcgaggauu cgaagucgug uauaugaccg     1620

aaccaaucga cgaauacugc guacaacaac uaaaagaguu cgauggcaag ucccucguau     1680

cagucacgaa agaaggccua gaacugccgg aagacgaaga agagaaaaag aaaauggaag     1740

aaagcaaagc aaaauucgaa aaccugugca aacucaugaa agaaauacuc gacaagaaag     1800

ucgaaaaagu aacaauaagc aaccggcuag ugagcagccc augcugcauc gucacaagca     1860

cauacggcug gacggcgaac auggaaagaa uaaugaaagc acaagcccua cgagacaaca     1920

gcacgauggg auacaugaug gcaaagaagc accuagaaau caacccagac cacccaaucg     1980

uggaaacacu ccgacaaaaa gccgaagcag acaagaacga caaggccgua aaagaucuag     2040

ugguacuacu guucgaaacc gcgcuacuca gcucaggauu cagccucgag gacccacaaa     2100

cccacucgaa caggaucuac agaaugauca aacuaggccu gggaauagac gaagacgaag     2160

ucgccgccga agaacccaac gcggcagucc cagacgaaau cccaccauug gagggagacg     2220

aagacgcaag caggauggag gaaguagacu aaggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  7029
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt8)

<400>  7029
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agggcguuau ggguccuagg gcugugcugc guccuccuga      120

cguucggcag cgucagagca gacgacgaag uggacguaga cggcaccgua gaagaagacc      180

ugggaaaauc cagagagggu agcagaaccg acgaugaagu cgugcagcga gaggaagaag      240

ccauccaacu cgacgggcug aacgcgucac agauacggga acuacgagag aaaagcgaaa      300

aauucgccuu ccaagcagaa gucaaccgaa ugaugaaguu aaucauaaac ucacuauaca      360

aaaauaaaga aauauuccuc agagaacuga uaagcaacgc gagugacgca cuagacaaaa      420

ucagacucau cagccucacc gacgaaaacg cccuuagugg gaacgaagaa cuaacaguca      480

aaaucaaaug cgacaaggaa aagaaccuac uacacguaac agacacgggu guaggaauga      540

cccgggagga acucgucaaa aaccucggca ccauagcgaa aagcggaaca ucagaguucc      600

ucaacaaaau gacagaggcc caggaagacg gacaaagcac cagcgaacug aucgggcaau      660

ucggaguagg auucuacagc gcguuccucg uggcagauaa ggucaucguc accucaaaac      720

acaacaacga cacccagcac auaugggaga gcgacagcaa cgaguucucc guaaucgcgg      780

acccccgcgg gaacacgcuc ggccgcggaa ccacaaucac acucguacuc aaagaagaag      840

caagcgacua ccuagagcuc gauacaauaa agaaccuggu gaaaaaguac agccaguuca      900

ucaacuuccc aaucuacgua uggagcagca aaacugagac gguagaagaa ccaauggaag      960

aagaggaagc agccaaagaa gaaaaagaag agucggacga cgaggcagcg guagaagaag     1020

aagaagaaga gaagaaaccg aaaaccaaga aaguagagaa aacgguaugg gauugggaac     1080

uaaugaacga caucaaaccc auauggcagc gccccagcaa agaagucgaa gaagacgaau     1140

acaaggcauu cuacaagagc uucagcaaag aaagugacga cccgauggcc uacauacacu     1200

ucaccgcaga aggggaagua acauucaaga gcauacuauu cgucccaacc ucagcgccgc     1260

gaggacucuu cgacgaguac gggagcaaga aaagcgacua caucaaacug uacguaagac     1320

gcguauucau aaccgacgac uuccacgaca ugaugcccaa auaccuaaac uuugugaaag     1380

ggguaguaga cagcgacgac cuaccccuaa acguguccag agaaacccuc cagcagcaca     1440

aacuccugaa gguaauaagg aagaaacugg ugcggaaaac acuagacaug auaaagaaaa     1500

uagccgacga caaguacaac gacaccuucu ggaaggaguu cggcaccaac auaaaacuag     1560

gggugaucga agaccauagc aaccggaccc gacucgcaaa acuccuaaga uuccaaucaa     1620

gccaccaccc caccgacaua acgagccucg accaguacgu ggaaaggaug aaggaaaagc     1680

aagauaaaau cuacuuuaug gcgggcuccu cccgaaaaga agcagaaagc ucacccuucg     1740

uagagcgacu acucaagaaa ggguacgaag uuauauaccu gacagaaccu guggacgaau     1800

acugcauaca agcacugccg gaguucgaug gcaaacgcuu ccaaaacgug gcaaaagaag     1860

gcguaaaauu cgacgaaagc gagaaaacga aagaaucacg cgaagcagua gaaaaagagu     1920

ucgaaccccu acucaauugg augaaagaca aagcauuaaa agacaaaaua gaaaaagcag     1980

uagugagcca acgcuugacc gaaagcccgu gugcccucgu agcaagccag uacggcugga     2040

gcgggaacau ggagagaauc augaaagcgc aggcguacca aacaggaaaa gacauaucca     2100

ccaacuacua cgcuucacaa aagaaaaccu ucgaaauaaa cccaagacau ccgcuaaucc     2160

gcgacaugcu gcgacgaaua aaggaggacg aagacgacaa gacaguacuc gaccucgcag     2220

ucguccucuu cgaaaccgca acgcuacggu caggcuaccu gcucccagac acgaaagcau     2280

acggagacag gauagagagg augcucagac uaagccuaaa cauagacccg gacgccaagg     2340

uagaagaaga accagaggaa gaaccggaag aaacggcaga agacaccaca gaggacacag     2400

agcaagacga ggacgaggaa auggacguag gaacugauga agaagaagaa acggccaaag     2460

aaucgacagc agaaaaggac gaacuauaag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  7030
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt8)

<400>  7030
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacgagaac uaagggcccu ccuccuuugg ggccgacgcc      120

uccgcccgcu acuucgcgcg ccagcacugg cagcuguccc aggaggcaaa cccauccuau      180

gcccccgccg aacaaccgca cagcucgguc ccagacgcaa cccagcuugg ucccuucaag      240

caggccgccu cuucuccacu caaacagcag aagacaaaga agaaccacuc cacagcauaa      300

ucucaucaac cgaaucagua caaggcucaa caucuaaaca cgaguuccaa gccgaaacua      360

agaaacugcu cgacauagug gccagauccc uauacuccga aaaagaaguc uucauccgcg      420

aauugaucuc aaacgcaucc gacgcacucg aaaaacuacg acacaaacuc gucuccgacg      480

gccaagcccu cccagaaaug gaaauccauc ugcaaacuaa cgccgaaaaa ggcaccauaa      540

caauccagga cacaggcauc ggcaugaccc aagaggaacu ugucuccaac cucggaacaa      600

ucgcccgcag cggauccaaa gcauuccucg acgcccuaca aaaccaagca gaagcaagcu      660

ccaaaaucau cggacaauuc ggagucggcu ucuacucagc cuucaugguc gccgaccgcg      720

ucgaagugua cucacgcuca gcugcacccg gaagucuagg cuaucaaugg cuaucagacg      780

gaagcggggu cuucgaaauc gcagaagccu cuggcgugcg cacaggcacc aaaaucauca      840

uccaccugaa auccgacugc aaagaguucu cgagcgaagc acgagucagg gacguuguaa      900

ccaaauacuc aaacuucgua uccuuuccac uauaccucaa uggccgucga augaacaccc      960

uccaagcaau cuggaugaug gacccuaaag acguaagaga auggcaacac gaagaguucu     1020

accgcuacgu ugcccaagcu cacgacaaac cacguuacac ccugcacuac aaaaccgacg     1080

caccccugaa uauccgaagc auuuucuacg uccccgacau gaaacccucu auguucgacg     1140

uaucccgcga acucggcucc ucagucgccc uauacucccg caaaguccuu auacaaacca     1200

aagccaccga cauacuccca aaauggcucc gcuuuauacg aggagucguc gacucagaag     1260

acaucccgcu caaccugagc cgagaacuac uccaagaauc cgcccucauu cgcaaacugc     1320

gugacguccu ccaacaacgc cucaucaaau ucuucaucga ccaaucaaag aaagacgccg     1380

aaaaauacgc uaaauucuuc gaagacuacg gccuauucau gcgcgaagga aucgugaccg     1440

ccacagaaca agaggucaaa gaagacauag ccaaacuccu aagauacgaa uccuccgcac     1500

ugcccucggg acaauuaacc ucacuauccg aauacgcaag ccguaugcgc gccgggaccc     1560

gcaacaucua cuaccucugc gcccccaacc gacaccuggc agagcacucc ccauacuacg     1620

aggcaaugaa aaagaaagac accgaagucc uuuucugcuu cgaacaauuc gacgaacuaa     1680

cccucuuaca ccuaagggag uucgacaaaa agaaacucau cucaguggaa acggacaucg     1740

uagucgacca cuacaaagaa gaaaaauucg aagaccgcuc accagccgca gaaugucuau     1800

ccgaaaaaga aacagaagaa cucauggccu ggaugcgcaa cguccuaggc agucgcguca     1860

caaacgucaa aguaacccuu agacuugaca cccaucccgc caugguaaca guccucgaaa     1920

ugggagccgc acgccacuuc cuaagaaugc agcaacuagc caaaacacaa gaagaaagag     1980

cccaacuccu acaaccuaca cuagaaauca acccccgcca cgcacucauc aagaaacuaa     2040

accaacuacg cgcaagcgaa ccaggccuag cgcaacuccu aguagaccaa aucuacgaaa     2100

acgccaugau agcagcaggc cuaguagacg acccccgcgc cauggucggc cgccucaacg     2160

aacuccuagu aaaagcccuc gaaagacacu aaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  7031
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt8)

<400>  7031
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaaaucu ccucacuccc cacacaacua uucaaaugcu      120

gcuucugcga cuuccucaaa gucaaaaugc acacaauguc cuccucacac cucuucuacc      180

uagcccucug ccuacucacc uucacaucau cagccacagc cggcccugaa accuuaugcg      240

gagccgaacu cguagacgcc cuccaauucg ucugcggaga ccgaggcuuc uacuucaaca      300

aacccaccgg uuacggauca ucaucccgcc gcgccccaca aacaggcauc gucgacgaau      360

gcugcuuccg cucaugcgac cuccgaagac uagaaaugua cugcgcaccc cucaaacccg      420

ccaaauccgc ccgcuccguc cgagcccaac gccacacaga caugcccaaa acacaaaaag      480

aaguccaccu caaaaacgcc ucccgaggau ccgccggcaa caaaaacuac cgcauguaag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  7032
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt8)

<400>  7032
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcauaccaa ugggcaaauc caugcuagua cuccuaaccu      120

uccuugccuu cgcauccugc ugcauagccg ccuaccgacc cuccgaaaca cucugcggcg      180

gcgaauuagu cgacacccua caauucgucu gcggcgaccg cggcuucuac uucucccgac      240

cagccucccg cgucuccaga cgcucacgcg gcaucguaga agaaugcugc uuccgaucau      300

gcgaccucgc ccuccucgaa accuacugcg ccacccccgc aaaaucagaa cgagacgucu      360

caaccccacc caccguccuc cccgacaacu uccccagaua ccccguaggc aaauucuucc      420

aauacgacac cuggaaacaa uccacccaaa gacuuagacg cggccucccc gcccuacucc      480

gagcccgccg cggacacgua cucgccaaag aacucgaagc cuuccgcgaa gccaaacgcc      540

accgcccacu caucgcccua cccacacaag accccgccca cggcggcgca cccccagaaa      600

uggccucaaa ccgaaaauaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  7033
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt8)

<400>  7033
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccacaucagc cuucggcccc gucgccuucu      120

cccucggacu ccuccuuguc cucccagccg ccuuccccgc cccagucccc cccggcgaag      180

acucaaaaga cguagccgcc ccccaccgac aaccccuuac cuccuccgaa cgcaucgaca      240

aacaaauacg auacauccua gacggcaucu cagcccuccg caaagaaacc ugcaacaaau      300

ccaacaugug cgaaucuucc aaagaagccc uagccgaaaa caaccucaac cuccccaaaa      360

uggccgaaaa agacggcugc uuccaaucag gauucaacga agaaaccugc cuugucaaaa      420

ucaucaccgg ccuccucgaa uucgaagucu accucgaaua ccuccaaaac cgcuucgaau      480

cauccgaaga acaagcccgc gccguccaaa ugucaacaaa aguccucaua caauuccucc      540

aaaaaaaagc caaaaaccuc gacgccauaa ccacccccga ccccaccacc aacgccucac      600

uacuaaccaa acuccaagcc caaaaccaau ggcuacaaga caugaccacc caccucaucc      660

uccgcuccuu caaagaauuc cuacaaagcu cccuccgcgc ccuacgccaa auguaaggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  7034
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt8)

<400>  7034
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuacuau ggcuccgcgg cuuccuacug gccucaugcu      120

ggaucaucgu acgcagcagc cccacaccag gaagcgaggg acacagcgca gccccagacu      180

gcccaagcug cgcccuagcg gcccugccaa aagacguacc caacagccaa cccgaaaugg      240

uagaagccgu caaaaaacac auacuaaaca ugcuacaccu aaaaaaaagg ccagacguaa      300

cacaacccgu cccaaaagca gcacuacuca acgcaauccg caaacuccac gucgggaaag      360

ucggagaaaa cggauacgua gagauagaag acgacaucgg gcgccgcgcc gaaaugaacg      420

aacucaugga acaaaccuca gagauaauca cguucgccga aagcggaaca gcccgcaaaa      480

cacuacacuu cgaaauaagc aaagaaggca gcgaccuaag cgucgucgag cgcgcagaag      540

ucuggcucuu ccucaaagua cccaaagcaa accgcacacg aacaaaaguc acaauacgac      600

uguuccagca acaaaagcac ccacaaggcu cccucgacac aggcgaagaa gcagaagaag      660

uaggccuaaa aggagaacgg agcgaacuac uccuaucaga aaaagucgua gacgcacgca      720

aaagcacgug gcacgucuuc ccaguaagca gcagcauaca acgacuacuc gaccaaggca      780

aaagcagccu cgacgucaga auagcaugcg aacaaugcca agaaucaggc gccucccucg      840

uccuacuggg aaaaaaaaag aaaaaagaag aagaaggcga aggaaagaaa aaaggcggug      900

gagaaggagg cgcaggagcg gacgaggaaa aagaacaauc ccaccgccca uuucuaaugc      960

ugcaagcacg gcaaucagaa gaccaccccc accgccgccg acgacgagga cuagaaugcg     1020

acggaaaagu caacaucugc ugcaaaaaac aauucuucgu cagcuucaaa gacauaggau     1080

ggaacgacug gauaauagcg ccaagcggau accacgcaaa cuacugcgaa ggcgaaugcc     1140

ccagccacau agcaggcaca agcgggagca gccugucguu ccacagcacc gugaucaacc     1200

acuacagaau gagaggacac uccccauucg caaaccugaa aucgugcugc guccccacca     1260

aacuacgacc gaugagcaug cucuacuacg acgacggaca gaacaucaua aaaaaagaca     1320

uacaaaauau gaucguggaa gagugcggau gcagcuaagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  7035
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt8)

<400>  7035
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccugc caggccgagc guuaggcgcc gccugccucc      120

uacuccuagc agcaggcugg cucggccccg aagccugggg aucaccaacc ccaccaccaa      180

cccccgcagc cccuccccca cccccaccac ccggcagucc cggcggauca caagauaccu      240

gcaccucaug cggcggauuc cgcagaccag aagaacucgg acgcguagac ggagacuucc      300

ucgaagccgu aaaaagacac auacuauccc gccuccaaau gcgcggccga cccaacauca      360

cacacgccgu ccccaaagcc gccaugguca ccgcccuacg caaacuacac gccggcaaag      420

uucgcgagga cggccgaguc gaaaucccac accucgacgg ccacgccucc cccggcgcag      480

acggacaaga acgaguuagc gaaaucaucu ccuuugccga aacagacggc cuagccucau      540

cacgaguccg acucuacuuu uucaucucca acgaaggaaa ccaaaaccuc uucgucguac      600

aagcaucccu auggcuauac cuaaaacucc uacccuacgu cuuagaaaaa ggaucccgcc      660

gcaaaguccg cgucaaaguc uacuuccaag aacagggcca cggcgaccgc uggaacaugg      720

ucgaaaaacg cguagaccuc aaacgcuccg gcuggcacac cuucccccua accgaagcca      780

uccaagcccu cuucgaacgc ggcgaacgac gccuaaaccu cgacguacag ugcgacucau      840

gccaagaacu cgccguagua cccguauucg ucgacccagg ggaagaaagc cacagaccau      900

ucgucgucgu ccaagccaga cucggcgacu cccgacaccg cauacgcaaa cgaggccucg      960

aaugcgacgg ccgcacaaac cucuguugcc gccaacaauu cuucaucgac uuccgccuaa     1020

ucgguuggaa cgacuggauu auagccccaa caggauacua cggcaacuac ugcgaagggu     1080

caugccccgc cuaccuagcc ggaguccccg gcucugccag cucauuccac acagcagucg     1140

ugaaccaaua ccgcaugcga ggccuaaacc ccggcaccgu aaacucuugc ugcaucccca     1200

caaaauuauc aaccaugucc augcuuuacu ucgacgacga auacaacaua gucaaacgcg     1260

acguccccaa caugauagua gaagaaugcg gcugcgccua aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  7036
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt8)

<400>  7036
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacuucgcg uccuccuccu uaccgcccua acccuauguc      120

auggauucaa ccucgacacc gaaaaugcca ugaccuuuca agaaaacgcc cgcggauucg      180

gccagucugu aguacagcuc caaggaucua gaguagucgu cggugccccu caagaaaucg      240

uagcagcaaa ccaacgcggu agucuauacc aaugugacua cucuacuggc ucgugcgaac      300

cuaucaggcu ccaagucccc guggaagccg ucaacauguc cuuaggacua ucacuggccg      360

ccaccaccuc cccaccgcaa cuccuagccu gcggacccac cguacaccaa acauguagcg      420

aaaacacgua cgucaaagga cucuguuuuc ucuucggcag caaccuacgc caacaacccc      480

aaaaauuccc ugaagcccuc agaggcugcc cacaagaaga cuccgacaua gccuuccuca      540

ucgacggauc cggcuccauu auaccccacg acuuccggag gaugaaagaa uuugucucga      600

cgguaaugga gcaacucaag aaaucaaaaa cacuguucag ccuaaugcaa uacucggagg      660

aguuccgaau ccacuucacc uucaaagagu uccaaaacaa ccccaacccc cguagccuug      720

uuaaacccau aacccaacua cugggccgaa cacacaccgc caccggcauc cgcaaagucg      780

uccgcgaacu auucaacaua accaacggcg cacgcaaaaa ugcuuucaag auacuuguag      840

uaaucacaga cggagaaaaa uucggagacc cauugggaua cgaagacguc auuccugaag      900

ccgaccgaga aggcguaauc agauacguga uagguguagg cgacgcauuc agaucagaaa      960

aaucacgcca agaacuaaac acaauagccu ccaagccacc ccgagaccau gucuuccagg     1020

uaaacaauuu cgaggcacuu aaaacuauuc agaaccagcu ccgugagaaa aucuucgcca     1080

ucgaaggaac ucagacagga uccuccucgu cuuucgaaca ugagaugagc caagaaggcu     1140

ucagcgcugc caucaccucu aacggacccu ugcuaucuac agucggcucc uacgacuggg     1200

ccggcggcgu guuccucuac accuccaaag aaaaauccac guucauaaac augacacgag     1260

ucgacucgga caugaaugac gcguaccuug guuaugcugc cgcaauuaua cuuagaaacc     1320

gugugcaauc ccuuguacuc ggcgcuccca gauaucaaca caucggccuc gucgcuaugu     1380

uucgucaaaa uaccgggaug ugggaaucca acgccaaugu caaaggcacc caaaucggcg     1440

ccuacuucgg cgcgagccua ugcucagucg acgucgacuc aaacggaucc accgaucuag     1500

uccugaucgg agcaccacac uauuacgaac aaaccagagg cggccaggua ucagucugcc     1560

cacucccccg aggccgcgcc cgcuggcaau gcgacgccgu ccuuuacggc gagcagggcc     1620

agccuugggg acgauucgga gccgcccuca ccguacucgg ugacguuaac ggagauaaac     1680

uaacagacgu cgcaaucggc gcccccggag aagaagacaa cagaggagcg gucuaccucu     1740

uucacggaac cuccgggagc ggaaucagcc cgucccauuc ccagcgcauu gcagguagca     1800

aacucagucc ccgccuccag uacuucggcc aaucccuguc cggcggccaa gaccuuacaa     1860

uggacggccu aguagaccuc accgucggug cucagggcca uguccugcuu cuacgcucuc     1920

aaccagucuu acgaguaaaa gcaauaaugg aguucaaccc acgcgaaguc gcccgcaacg     1980

ucuucgaaug caacgaccag gucguaaaag gcaaagaagc cggagaaguc cguguaugcc     2040

ugcacguaca aaaguccacc cgcgaccgcc uacgggaagg ccaaauacag ucugucguca     2100

cuuaugaccu cgcucucgac uccggaagac cgcacucucg ggccgucuuu aacgaaacca     2160

aaaacucaac acgacgacaa acacaggugc ucggccugac gcagacaugc gagacgcuca     2220

aauugcagcu accaaacugc aucgaagacc caguaagccc uauuguccuu cgccuaaacu     2280

ucagccucgu ggggacacca cuaagcgccu ucggcaaccu acgcccggua cucgcggaag     2340

acgcccagcg ccucuucacc gcccuuuuuc ccuucgagaa aaacugcggc aacgauaaca     2400

ucugccaaga cgaucugucg aucaccuuca gcuucauguc ccucgacugu cucguagucg     2460

gaggcccccg ugaguucaac guaaccguaa ccguccgcaa cgacggagaa gacagcuacc     2520

gcacucaggu caccuuuuuc uucccccucg accugucuua cagaaaagua ucaacacucc     2580

aaaaccaacg aucccaacgu ucauggcgac uagccugcga auccgccagc uccacugaag     2640

ucagcggcgc ccucaaaagc acguccugcu cgaucaacca ccccauauuc cccgagaacu     2700

cagaagucac auucaacauc acauucgacg uagauucaaa ggcuucacuc ggaaauaaac     2760

ugcuucucaa agccaacguc accucagaaa auaauaugcc ccguacuaac aaaaccgagu     2820

uucaacuaga acucccgguc aaauacgccg ucuacauggu aguaaccucu cacggaguau     2880

ccaccaagua ccucaacuuc acugcauccg aaaacacuuc ucgcgucaug cagcaccaau     2940

aucaagucuc caaccucggu caacguucac ugcccaucuc ccuaguauuc cuggucccag     3000

uacgccuaaa ccagaccguc auaugggaca gaccccaagu caccuucuca gaaaaccuua     3060

gcucuaccug ccauacaaag gaaagauuac ccucacacuc cgacuuucuc gcagagcuca     3120

ggaaagcccc cguagucaac ugcucgauag caguaugcca acgaauacaa ugcgauaucc     3180

cauucuuugg cauccaggaa gaguucaacg ccacccugaa ggguaaccuc ucauucgacu     3240

gguacauaaa gacaucacau aaccaucuac uuauagucag cacagccgaa auccuguuca     3300

acgacucagu guucacccuc cugcccggcc aaggagccuu cguacgcuca caaaccgaaa     3360

caaaaguuga accuuucgaa guucccaacc cccuuccgcu cauagucggc uccucagucg     3420

gaggccuccu ccuacucgcc cuaauaaccg cagccuugua caaacucgga uucuucaaac     3480

gccaguacaa agacaugaug ucagaaggag guccucccgg cgcagaacca caauagggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  7037
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt8)

<400>  7037
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucacuaa aaacccuacc cuuucuccua cuccuucacg      120

uccagauauc aaaagccuuc cccgucuccu cuaaagagaa aaacaccaaa accgugcaag      180

acuaccucga aaaauucuac caacucccgu ccaaccaaua ccaaucaaca cgcaaaaacg      240

gcacuaacgu aaucgucgaa aaauugaaag aaaugcaacg auucuucggc cucaacguca      300

ccggcaaacc caacgaagaa acccucgaca ugaugaagaa accccgaugc ggaguacccg      360

acucuggcgg cuucaugcuc acucccggca aucccaaaug ggaacgcacu aaccucaccu      420

accgcaucag aaauuacaca ccccaacucu cagaagccga agucgaaaga gcgauuaaag      480

acgcauucga acuauggucc gucgccagcc cccuaaucuu cacccgcauc ucccaaggug      540

aagccgacau caacauagca uucuaccaac gcgaccacgg ugacaacucc ccauucgacg      600

gcccaaacgg cauacuugcc cacgcauucc aacccgguca aggaaucgga ggcgacgccc      660

acuucgacgc cgaagaaacc uggaccaaca cauccgcaaa cuacaaccua uuccucguug      720

ccgcccacga guucggccac ucccuaggcu uagcacacuc cuccgaucca ggugcccuaa      780

uguauccaaa cuacgccuuc cgcgaaaccu ccaauuacuc ccuaccccaa gaugacaucg      840

acggaaucca agcaaucuac ggacucucau ccaaccccau ccaacccacc gguccaucaa      900

ccccaaaacc cugcgacccc ucccucaccu ucgacgcaau caccacucuc agaggugaaa      960

uccucuucuu caaagaccgu uacuucuggc gaagacaccc acaacuccaa cgcgucgaaa     1020

ugaacuuuau uucacucuuc uggcccucgc uucccaccgg cauccaggcc gcauacgaag     1080

acuucgaccg cgaccuaauc uuccucuuca aagguaacca auacugggca cuaucaggcu     1140

acgacauccu ucaaggcuac cccaaagaca uauccaacua cggcuuccca uccuccgucc     1200

aggcaaucga cgcugcaguc uucuauagau ccaaaaccua cuucuucguc aacgaccaau     1260

ucuggcgaua cgacaaccaa cgacaauuca uggaacccgg cuaccccaaa ucaaucuccg     1320

gcgcuuuccc cggcaucgaa uccaaagucg acgccguuuu ccaacaagaa cacuucuucc     1380

acgucuucuc cgggccacga uacuacgccu ucgaccucau cgcccaacgc gucacccgag     1440

uagcacgcgg caacaaaugg cuuaacugcc guuacggcug aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  7038
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt8)

<400>  7038
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucccucuggc aaccccuagu ucuaguccuc cucguacuug      120

gaugcugcuu cgcagcaccc cgacaacgcc aauccacccu aguccucuuc ccuggcgauc      180

uucgaacaaa ccugaccgac cgccaacucg cggaagaaua ucucuaccgc uacggcuaca      240

cacguguagc cgaaaugcgc ggagaaucca aaagccuagg uccagcacuc cuccuccucc      300

aaaaacaacu uucacucccc gaaacgggcg aacucgacuc cgccacccuc aaagcaauga      360

gaacaccacg cugcggggua cccgacuuag ggagauucca aacguucgaa ggagaccuaa      420

aguggcacca ccacaacaua acuuacugga uacaaaacua cagcgaggac cugccccgag      480

cagucaucga cgacgccuuc gcaagagccu ucgcccuaug gagcgccgua acaccccuca      540

ccuucacccg uguauacucc cgagacgccg acauugucau ccaauucggc guagccgaac      600

acggagacgg cuacccauuc gacggcaaag acggccuauu ggcacacgca uuuccacccg      660

gcccaggaau acaaggcgac gcccacuuug acgaugacga acucuggagc cugggaaaag      720

gagucguagu ccccaccaga uucggcaacg cagacggagc agcaugccac uuccccuuua      780

uauucgaagg ccgcucuuac agcgccugca cuaccgaugg ccgcuccgau ggucuacccu      840

ggugcuccac caccgccaac uacgacaccg augaucgcuu cgguuucugu ccaucugaaa      900

gacucuacac ccaggacggc aacgccgacg gcaaacccug ccaauuucca uucaucuucc      960

aaggccaauc uuacuccgca ugcaccacag acggccgauc cgauggauau cgcuggugcg     1020

ccacaacugc caauuacgac cgagacaaac ucuucggauu cugcccaacc cgagcagacu     1080

caaccguaau gggaggaaac ucagccggcg aauuaugcgu auuucccuuc accuuccucg     1140

gaaaagagua cuccacgugc accagcgaag gccgaggaga cggacgacua uggugcgcca     1200

ccacaucaaa cuucgacucc gacaagaaau ggggcuucug ccccgaucaa ggcuacucuc     1260

uguucuuagu cgccgcacac gaguucggac acgcccuggg acuagaccac aguucagucc     1320

ccgaagcgcu cauguacccc auguaccgcu ucacagaagg accaccacua cacaaggacg     1380

acguaaacgg caucagacac cuauaugguc cccgaccaga acccgaacca cgcccuccca     1440

cuaccacuac cccacaacca acugccccac ccacaguaug uccaacagga ccacccaccg     1500

uacaccccuc cgaacgcccc accgccggcc cuaccggacc ucccuccgca ggucccacag     1560

gaccacccac agccggcccc uccaccgcca ccacaguucc cuuauccccu gucgacgacg     1620

caugcaacgu caacauauuc gacgcuaucg ccgaaaucgg caaucaacua uaccuguuca     1680

aggacggcaa auauuggcgc uucucagaag gccgaggcag ccgcccucaa gguccauucc     1740

ucauugccga caaauggccc gcccucccca gaaaacuuga cuccgucuuc gaagaacguc     1800

ucuccaagaa auuauucuuc uucucaggcc gucaagucug ggucuacacc ggcgccagcg     1860

uccucggccc cagacgucua gacaaacuug gacucggagc cgacgucgcu cagguaaccg     1920

gggcucugcg auccggacgc gggaagaugu ugcuauucag cggacgcaga cuauggcgcu     1980

ucgacgucaa agcccaaaug gucgacccga gauccgccuc cgaaguugac cguauguucc     2040

caggcgugcc ccucgacacc cacgacguau uccaauaccg cgaaaaagca uacuucugcc     2100

aggaccgcuu uuauuggcga gucucuuccc gaucugaacu uaaccaaguc gaccaaguag     2160

gauaugucac cuacgacauc cuccagugcc ccgaggacua aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  7039
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt8)

<400>  7039
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacccaggcg uccucgcagc uuuccucuuc cucuccugga      120

cacacugccg cgcauuaccc cuccccucag gaggcgacga agacgaccuc uccgaagagg      180

accuccaauu cgccgaacgu uaccuccgcu ccuacuacca cccgacaaac cucgcaggaa      240

uacucaagga aaacgccgcc uccuccauga ccgaacgccu uagagaaaug cagucauucu      300

ucggccuaga aguaaccgga aaacuagacg acaacacccu agacgucaug aaaaaacccc      360

gaugcggugu ccccgacguc ggcgaauaca acgucuuccc ccgcacccuu aaguggucca      420

aaaugaaccu gaccuaucgc auagucaacu acacgccaga caugacccau uccgaagucg      480

aaaaagcauu caaaaaagcg uucaaaguau gguccgacgu caccccacuu aacuucacac      540

gccuccacga cggaaucgca gacaucauga uaagcuucgg uaucaaagaa cacggcgacu      600

ucuaccccuu cgacggccca ucaggccuac uagcccacgc auuccccccc ggcccgaauu      660

acggcggcga cgcccacuuu gacgaugacg aaaccuggac auccuccucc aaagguuaca      720

accuauuccu aguagccgca cacgaauucg gccacucccu cgggcuagac cacuccaaag      780

accccggagc ccucauguuc cccauauaca cuuacaccgg caaaucccac uucaugcuac      840

ccgacgacga cguacaaggc auccaauccc uguacggccc aggcgacgaa gacccaaacc      900

ccaaacaccc caaaacuccc gacaaaugcg accccucccu cucccuagac gccaucaccu      960

cacuccgcgg cgaaacaaug auauucaaag accguuucuu cuggcgccuc cacccacaac     1020

aaguagaugc agaacucuuc cuaacaaaau ccuucuggcc cgaacuacca aaccgaaucg     1080

acgcugcaua ugaacaucca ucccacgacc ucauuuucau auuucgaggc cgaaaauucu     1140

gggcacuaaa cgguuacgac auccucgaag gcuaccccaa aaaaaucucc gaacuaggcc     1200

uucccaaaga aguaaaaaaa aucucagccg ccguccacuu ugaagacacc ggaaagacuc     1260

uacuauucuc aggcaaccaa gucuggcgau acgacgacac caaccacaua auggacaaag     1320

acuaccccag gcuaauagaa gaagacuuuc caggcaucgg agacaaagua gacgccguau     1380

acgagaaaaa cggcuacauc uacuucuuca acggccccau acaauucgag uacuccaucu     1440

gguccaaucg aaucguacgc gucaugcccg ccaacucaau ccucuggugc uaaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  7040
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt8)

<400>  7040
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gagaccccca acaccacaga agacuacgac accaccaccg      120

aauucgacua cggugacgcc acccccuguc aaaaagucaa ugaacgcgcc uucggcgcac      180

aacuacuacc gccccucuac ucgcucguuu ucguaaucgg ccucgucgga aauauacucg      240

ucguccucgu ccuaguccaa uacaaacgcc ucaaaaacau gacuucaauc uaccuccuua      300

accuagccau cucugaccuc cucuuccuau ucacacuccc auuuuggauc gauuacaaac      360

ucaaagacga cugggucuuc ggcgacgcaa ugugcaaaau ccuaucaggc uucuacuaca      420

ccggccuaua uagcgaaauc uucuucauua uccuucucac caucgaccgc uaccucgcca      480

uaguccacgc agucuucgcc uugcgcgcac gcaccguaac uuuuggaguc auaaccucca      540

ucaucauuug ggcucucgcc auccucgccu caaugcccgg ccuauacuuc uccaaaacac      600

aaugggaauu cacccaccau acuugcuccc uccacuuccc acacgagucc cuaagagaau      660

ggaaacucuu ucaagcacuc aaauuaaacc ucuuuggucu cguucuuccc cuccucguca      720

ugauaauuug cuacaccggc aucaucaaaa uccuccuccg ccguccaaac gaaaaaaaau      780

ccaaagccgu ccgccuaauc uucguaauaa ugaucaucuu cuuccucuuc uggacccccu      840

acaaccucac aauccucauc uccgucuucc aagauuuccu cuucacccac gaaugcgaac      900

aaucucguca ccucgaccuc gcuguccaag ucacagaagu caucgcuuac acacacugcu      960

gcgucaaccc cguaaucuac gcauucgucg gugaacgauu ccgcaaauac cuccgccaac     1020

ucuuccaccg ccgcguagcc guccaccucg ucaaauggcu ucccuuccuc uccgucgacc     1080

gacucgaacg cguaucuagc accuccccuu ccacaggaga acacgaacuc uccgccggcu     1140

ucuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  7041
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt8)

<400>  7041
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcacccucg ccugccuccu ccuccucggc ugcggcuacc      120

ucgcccacgu ccucgccgaa gaagccgaga ucccacgcga aguaaucgaa cgccucgccc      180

gcucccaaau acacuccauc cgcgaccucc aacgccuccu cgaaaucgac ucaguaggcu      240

ccgaggacuc acucgacacc ucacuccgcg cccacggcgu ccacgccacc aaacacgucc      300

ccgaaaaaag accacuccca auccgacgaa aacgauccau cgaagaagcc guccccgcag      360

ucugcaaaac ccgcaccguc auauacgaaa ucccacgauc ccaagucgac cccaccuccg      420

ccaacuuccu aaucuggccc ccaugcgucg aagucaaacg augcaccggc ugcugcaaca      480

cauccuccgu aaaaugccaa cccagccgcg uccaccaccg cuccguaaaa guagcaaaag      540

ucgaauacgu acgcaaaaaa cccaaacuaa aagaagucca aguccgccuc gaagaacacc      600

uagaaugcgc augcgcaaca acaucccuaa accccgacua ccgcgaagaa gacaccggcc      660

gaccacgaga auccggcaaa aaacgcaaac gcaaacgccu caaaccaaca uaaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  7042
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt8)

<400>  7042
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaccgaugcu gggcacucuu ccuaucccuc ugcugcuacc      120

uacgccuagu cucagccgaa ggcgacccca uccccgaaga acucuacgaa augcucagcg      180

accacuccau ccgaagcuuc gacgaccuuc aacgccuacu ccacggcgac cccggcgaag      240

aagacggagc cgaacucgac cuaaacauga cccgcuccca cuccggcgga gaacucgaau      300

cacucgcacg cggacgcaga ucccucggcu cccucaccau cgccgaacca gccaugauag      360

cagaaugcaa aacccgaaca gaagucuucg aaaucucacg ccgccucaua gaccgaacca      420

acgccaacuu ccucgucugg cccccaugcg ucgaagucca aagaugcucc ggcugcugca      480

acaaccgcaa cguccaaugc cgcccaaccc aaguccaacu ccgcccaguc caaguacgca      540

aaaucgaaau cguacgcaaa aaaccaaucu ucaaaaaagc caccgucacc cuagaagacc      600

accucgccug caaaugcgaa accguagccg cagcccgacc cguaacacgc ucucccggcg      660

gcagccaaga acaacgagca aaaacacccc aaacacgcgu cacaaucagg accguccgcg      720

uccgcagacc cccaaaaggc aaacaccgca aauucaaaca cacccacgac aaaaccgcac      780

ucaaagaaac ccuaggcgca uaaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  7043
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt8)

<400>  7043
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucccucuucg gccuccuccu ccucaccuca gcccuagcag      120

gccaacgcca aggcacccaa gccgaaucca accucuccuc caaauuccaa uucucaucca      180

acaaagaaca aaacggcgua caagacccgc aacaugaacg cauaaucacc guauccacca      240

acggcagcau ccacucccca agguuccccc auaccuaccc ccgcaacacc guccuagucu      300

ggcgccuugu cgccgucgaa gaaaacgucu ggauccaacu gacauucgac gaacgcuucg      360

gccucgaaga ccccgaagac gacaucugca aauacgauuu cgucgaagua gaagaaccuu      420

ccgauggcac cauccucggc cgcuggugcg gaagcggcac cguccccggc aaacaaaucu      480

caaaaggcaa ccaaauacgc auccgauucg ucuccgacga auacuuccca ucagaacccg      540

gauucugcau acacuacaac aucgucaugc cacaauucac cgaagccguc ucacccuccg      600

uccuaccccc cucagcccuc ccccucgacc uacucaacaa cgccauaaca gccuuuucca      660

cccucgaaga ccucauccga uaccucgaac cagaacgaug gcagcucgac cuagaagacc      720

ucuaccgccc caccuggcaa cucuuaggca aagccuucgu cuucggccgc aaaucgcgcg      780

uaguugaccu uaaccuccua accgaagaag uacgccucua cagcugcacc ccacgcaacu      840

ucuccguauc aauccgcgaa gaacucaaac guaccgacac cauauucugg cccggaugcc      900

uccuagucaa aagaugcggc ggaaacugcg ccugcugccu ccauaacugc aacgaaugcc      960

aaugcguacc cuccaaagua accaaaaaau accacgaagu ccuucaacuc cgcccaaaaa     1020

caggcguacg uggccuccau aaaucacuua ccgacgucgc ccucgaacac cacgaagaau     1080

gugacugcgu cugucgcgga uccaccggag gauaaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  7044
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt8)

<400>  7044
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgccuca ucuucgucua cacccuaauc ugcgccaauu      120

ucugcucaug ccgcgacacc ucugccacac cgcaaagcgc uucaaucaaa gcacuccgga      180

acgccaaccu gcgacgagac gaccucuacc gccgcgacga aaccauccaa gucaaaggaa      240

acggcuacgu acaaagcccc cgauucccaa acuccuaccc ccgcaaccuc cuacucaccu      300

ggagacuaca cucccaagaa aacacccgaa uacaacucgu auucgacaac caauucggac      360

uagaagaagc ugaaaacgac aucugccgau acgacuucgu agaagucgaa gacauaagcg      420

aaacauccac aaucaucaga ggccgcuggu gcggccacaa agaaguacca ccccgcauca      480

aaucccgcac aaaccaaauc aagauaaccu ucaaaucaga cgacuacuuc gucgccaaac      540

ccggauucaa aaucuacuac ucccuccuag aagacuucca acccgccgcc gccuccgaaa      600

caaacuggga aucagucacc ucaagcaucu cagguguauc auacaacucc cccuccguca      660

ccgaccccac acucauagca gacgcccucg acaagaaaau agcugaauuu gacaccgucg      720

aagaccuccu caaauacuuc aaccccgaau ccuggcaaga agaccucgaa aacauguacc      780

uggauacacc acgcuacaga ggccgaucau accacgaccg aaaaaguaaa gucgaccuug      840

accgccucaa cgacgacgcc aaacgcuaua gcugcacccc ucgaaacuac uccgucaaca      900

uccgagaaga acuaaaacuc gcaaacgucg uauucuuccc acguugccuc cuuguccagc      960

gaugcggagg caacugcggc ugcggcaccg ucaacuggcg gagcugcaca ugcaacuccg     1020

gcaaaaccgu aaagaaauac cacgaaguac uccaauucga accaggucac aucaaacguc     1080

gcggcagagc uaaaaccaug gcauuagucg acauacaacu agaccaccac gaacgaugcg     1140

acugcaucug cagcucacga cccccacgcu aaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  7045
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt8)

<400>  7045
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacacacu ccaaauuccc cgccgccggc augucccgac      120

ccuuagacac cuccuuacgc cuaaaaaccu ucuccuccaa auccgaauac caacucguag      180

ucaacgcagu acgcaaacuc caagaauccg gauucuacug gucagccgua accggcggcg      240

aagccaaccu ccuccuaucc gccgaaccag ccggcaccuu ccuaauucgc gacucauccg      300

accaacgcca cuucuucacc cucuccguca aaacccaauc cggcacaaaa aaccuccgca      360

uccaaugcga aggcggauca uucuccuuac aauccgaccc ccgcuccacc caaccagucc      420

cccgauucga cugcguacuc aaacucgucc accacuacau gccacccccc ggcgcccccu      480

ccuucccuuc accccccacc gaacccuccu ccgaaguccc ugaacaaccc ucagcccaac      540

ccuuacccgg cuccccccca cgccgcgcau acuacaucua cucaggcggc gaaaaaaucc      600

cacucguccu cucccgcccc cucuccucca auguagccac acuccaacac cucugccgca      660

aaaccgucaa cggccaccua gacuccuacg aaaaaguaac ccaacucccc ggacccauac      720

gcgaauuccu agaccaauac gacgccccac uauaaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  7046
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt8)

<400>  7046
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guccccuccg ccggccaacu cgcccucuuc gcccucggca      120

uaguacucgc agccugccaa gcccuagaaa acucuaccuc cccccucucc gccgaccccc      180

caguagcagc cgccgucguc ucacacuuca augacugccc agacucccac acccaauucu      240

gcuuccacgg caccugccgc uuccucguac aagaagacaa acccgccugc guaugccauu      300

ccggauaugu cggcgcccgc ugcgaacacg ccgaccuccu agcaguaguc gcagcaucac      360

aaaaaaaaca agcaaucaca gcacuugucg ucgucucaau cgucgcccuc gccguacuaa      420

ucaucaccug cguccucauc cacugcugcc aaguccgaaa acacugcgaa uggugccgag      480

cacucaucug ccgccacgaa aaacccucag cccuacucaa aggccgaacc gcaugcugcc      540

acuccgaaac agucgucuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  7047
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt8)

<400>  7047
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccuccauccg gccuacgacu acuccccuua cuccuacccc      120

uccuauggcu ccuaguccua acacccggcc gccccgcagc cggccuaucg accugcaaaa      180

ccaucgacau ggaacucguc aaacgcaaac gcaucgaagc cauucgagga caaauccuau      240

ccaaacucag acucgccuca ccucccuccc agggcgaagu accacccggc ccccuucccg      300

aagcaguccu cgcccucuac aacucaacaa gagaccgcgu cgccggcgaa uccgccgaac      360

ccgaacccga acccgaagcc gacuacuacg ccaaagaagu uacccgagug cuaauggucg      420

aaacccacaa cgaaaucuac gacaaauuca agcagucaac acacucaaua uacauguucu      480

uuaauaccuc agaacuccgc gaagcaguac cugaacccgu ccuccuaucc cgcgccgaac      540

uccgacuucu cagacucaaa cuuaaggucg aacaacacgu cgaacucuac caaaaauacu      600

ccaauaauuc auggcgcuac cucuccaauc gacuccuugc ccccuccgac ucacccgaau      660

ggcucuccuu cgacgucacc ggagucguac gccaguggcu cucccgcggc ggcgaaaucg      720

aaggcuuccg ccucuccgca cacugcuccu gugacucccg cgacaauacc cuacaagucg      780

acaucaacgg cuucaccacc ggccgacgcg gcgaucucgc caccauccac ggcaugaacc      840

gcccauuccu ccuccuaaug gccacacccc ucgaacgugc ccaacaucug caaucauccc      900

gccaccgacg ugcccucgac accaacuacu gcuucuccuc aaccgagaaa aauugcugcg      960

uacgacaacu auacaucgac uuccgcaaag accucggaug gaaguggauc cacgaaccca     1020

aaggauacca cgccaacuuc ugccucggcc ccugccccua caucuggucc cucgacacac     1080

aauacuccaa aguucucgcc cucuacaacc aacacaaucc cggcgcauca gcagcccccu     1140

gcugcguccc ccaagcccua gaaccccucc caaucgucua cuacgucggc cgaaaaccaa     1200

aagucgaaca auuauccaac augaucgucc gcagcugcaa augcuccuga ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  7048
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt8)

<400>  7048
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uacucuccgc auuccucaua cuccaccucg      120

ucaccgucgc cuuaucuuua uccacaugcu caacccucga cauggaccaa uucaugcgca      180

aacgcaucga agccauccga ggacaaaucu uaucaaaacu caaacuaacc uccccacccg      240

aagacuaccc cgaaccagaa gaagucccac ccgaagucau uuccauuuac aacuccacac      300

gcgaccugcu acaagaaaaa gccucccgcc gcgccgccgc augcgaacgc gaacgcucag      360

acgaagaaua cuacgccaaa gaagucuaca aaaucgacau gccacccuuc uuccccuccg      420

aaaacgccau cccacccacc uucuacagac ccuacuuccg uaucguccgc uuugacguca      480

gcgcaaugga gaaaaacgcc aguaaccuug ucaaagccga guuccgagua uuccgccuac      540

aaaacccaaa agcccgcguc ccagaacaac gcaucgaacu cuaccaaauc cuaaaaucca      600

aagaccuaac uucucccacc caacgauaca uagacucaaa aguugucaag acccgcgcag      660

aaggugaaug gcucagcuuc gacguaacug acgccgucca cgaauggcua caccauaaag      720

accgaaaccu aggcuucaaa auaagccucc acugcccaug cugcacauuc guccccucga      780

acaacuauau caucccgaac aaaucagagg aacuggaagc ccgcuucgcc ggaaucgacg      840

gaaccuccac cuacaccucc ggcgaccaga aaaccauuaa aucaacccgc aaaaagaaca      900

gcggaaaaac cccacaccuc cuacucaugc uacuaccauc cuaccgacua gaaucacaac      960

aaaccaaccg cagaaagaaa cgcgcccucg augccgccua cugcuucagg aacguccaag     1020

acaacugcug ccuacgcccc cuauacaucg acuucaaacg cgaccucgga uggaaaugga     1080

uccacgaacc uaaaggcuac aacgcaaacu ucugcgccgg agcaugcccc uaccucugga     1140

gcuccgacac acaacacucu cgcguccucu cccuauacaa caccaucaac cccgaagccu     1200

ccgccucacc cugcugcguc ucccaagacc ucgaaccccu cacaauacua uacuacaucg     1260

gcaaaacccc caaaaucgaa caacugucca acaugaucgu caaauccugc aaaugcagcu     1320

agggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  7049
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt8)

<400>  7049
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaugcacc uccaacgcgc ccucguaguc cucgcccucc      120

ucaacuucgc cacagucagc cucucccuau caaccugcac cacccuagac uucggccaca      180

ucaaaaagaa aagagucgaa gccauccgcg gccaaauccu cuccaaacuc cgucucacca      240

gcccacccga acccaccguc augacccacg ucccauacca aguccucgcc cuauacaacu      300

ccacgcgcga acuacuagaa gaaaugcacg gagaaagaga agaaggaugc acccaagaaa      360

acacagaauc agaauacuac gcaaaagaaa uccacaaauu cgacaugauc caaggacucg      420

ccgaacacaa cgaacucgcc gugugcccca aaggcaucac cucuaaaguc uuccgauuca      480

acgucuccuc aguagagaaa aaccgcacca accucuucag agccgaguuc cgaguccuca      540

gaguccccaa ccccucuuca aaacgcaacg aacaacgcau ugaacuguuc caaauccuac      600

gaccagacga acacaucgcu aaacaacgau acauaggagg caaaaaccug cccacccgag      660

gaacagcaga auggcucucc uucgacguca ccgacaccgu ccgcgaaugg cucuuacgcc      720

gagaauccaa ccuuggacua gaaaucucca uacacugccc cugccacacc uuccagccca      780

acggagacau acucgaaaac auccacgaag ucauggaaau caaauucaaa ggaguagaua      840

acgaagacga ccacggacgc ggcgaccucg gccgacucaa gaaacaaaaa gaccaccaca      900

acccgcaccu cauacugaug augaucccac cccaucgccu cgauaacccc ggccagggcg      960

gccaacggaa gaaacgagca cucgacacca acuauugcuu cagaaaccuc gaagaaaacu     1020

gcugcgucag accccucuac aucgacuucc gccaagaccu aggcuggaaa uggguacacg     1080

aaccaaaagg cuacuacgcc aacuucugca gcggacccug cccauaccuc cgaucggcag     1140

acaccaccca cucaaccguc cucggccucu acaacacccu uaaccccgaa gcauccgcau     1200

cccccugcug cguaccgcaa gaccuagaac cccucaccau acuauacuac gucggccgaa     1260

ccccaaaagu cgaacaauua uccaacaugg ucgucaaauc cugcaaaugc agcuaaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  7050
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt8)

<400>  7050
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaccaguag ccgucugggc cgccuuggcc guuggccuag      120

aacucugggc cgcagcccac gcccugccag cccaagucgc auucaccccu uacgcccccg      180

aacccggcag cacaugccga cuccgcgaau acuacgacca aacggcacag augugcugcu      240

cuaaaugcag cccaggccaa cacgcaaaag ucuucuguac aaaaaccagc gacaccguau      300

gcgacuccug cgaagacucc acuuauaccc aacucuggaa cugggucccc gaaugccucu      360

cuugcggcag ccgcugcuca uccgaucaag ucgaaaccca agccuguacc cgcgaacaaa      420

acagaaucug uaccugcaga cccggcuggu acugcgcccu cuccaaacaa gaaggaugcc      480

gacuaugcgc cccucuccgc aaaugccgcc caggauucgg cguagcacgc cccggcaccg      540

aaaccucaga cgucgucugc aaaccuugug cgcccggaac auucagcaac accaccucau      600

ccaccgacau cugcagaccc caucaaauau gcaacgucgu cgcuaucccc ggaaacgcau      660

caauggacgc ugucugcacc ucaaccucuc ccaccagauc cauggcacca ggggccgucc      720

accuacccca acccgucucc acucgauccc aacacaccca acccacacca gaaccgucca      780

ccgccccauc caccuccuuc cuccucccca ugggcccauc cccgcccgcc gaagguucua      840

ccggagacuu cgcccuuccc gucggccuua ucgucggugu caccgcacuc ggacuccuca      900

ucauaggcgu cgucaacugc gucaucauga cacaaguaaa gaagaaacca cuuugccuac      960

aacgagaagc caaaguaccc caccuccccg cagacaaagc ccguggcacc caaggacccg     1020

agcaacaaca ccuccuaaua accgcccccu cauccuccuc cucaucacuc gaaucauccg     1080

ccucagcacu cgaccgcaga gcgcccaccc gcaaccaacc acaagccccc gguguagaag     1140

ccuccggcgc uggcgaagcc cgcgccucca caggaucuuc cgacucuuca cccggcggcc     1200

acggcaccca agucaacgua accugcauag ucaacguaug cuccuccucc gaccacuccu     1260

cacaaugcag uucccaagca ucaucaacaa ugggagacac agacuccucc cccuccgaau     1320

ccccaaaaga cgaacaaguc ccauuuucaa aagaagaaug ugccuucaga ucccaacucg     1380

aaacaccaga aacccuacuu ggcuccacag aagaaaaacc ccucccccua ggcguucccg     1440

acgcuggcau gaaaccaucc uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  7051
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt8)

<400>  7051
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggucauga gauuguuccc gugcuuucuc cagcuauugg      120

ccggguuagc acuaccggca gugcccccac aacagugggc gcucucggcc gggaacggga      180

gcucggaagu ggaaguggua ccauuccagg aagugugggg gcgcucguac ugucgagcgc      240

ucgagcgauu gguagauguc gugagcgagu acccaagcga gguagagcac auguucucac      300

ccucaugcgu gagcuugcuc aggugcacgg gcuguugcgg ggacgagaac uugcacugug      360

ucccgguaga gaccgcgaac gugaccaugc aacugcucaa gaucagaagc ggggacaggc      420

ccucguacgu ggaauugacc uuuagccagc acgugcgcug ugaaugucgc ccgcucagag      480

aaaagaugaa gcccgagcgc agacgaccga aagggcgcgg gaaaaggcgc agggaaaagc      540

aaaggcccac ggacugucac uugugcgggg acgcgguccc gcgcagguaa ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  7052
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt8)

<400>  7052
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgaccgcc agaccgacac cgcgcccucg ccaucauacc      120

aucucuugcc cggacgcagg agaacagucg augccgcggc aucgcgaggg caaggaccag      180

agcccgcacc aggaggaggg gucgaggggg uaggagcgcg cggaguagcg cucaaacugu      240

ucguacaacu gcuaggcugc aguagguucg ggggagcggu cguacgcgcg ggggaggccg      300

aaccaagcgg cgcggccaga agcgcaagca gcggcaggga agaaccacag cccgaggaag      360

gagaagagga agaggaaaaa gaagaggaaa ggggcccaca guggcgacug ggagcgcgca      420

agcccgggag cuggaccgga gaagcggcag ugugcgcgga cucggccccg gcagcacgcg      480

cgccacaggc ccuggccaga gccucaggca ggggcgggcg cguggccagg cgcggggcag      540

aagaaucagg accgccccac agcccaagca ggcgagggag cgcaaguagg gccgggcccg      600

gccgcgcgag cgaaaccaug aacuuccucc ugagcugggu ccacuggucg cucgcgcuau      660

ugcucuaccu ccaccacgcg aaauggagcc aggccgcgcc cauggcagaa ggaggcgggc      720

agaaccacca cgagguagug aaauucaugg acguauacca aaggagcuac ugccacccca      780

uagaaacgcu uguggacaua uuccaagaau accccgacga aaucgaauac auauucaaac      840

cgagcugcgu cccacucaug cgcugcggag ggugcugcaa cgacgaaggg cucgaaugcg      900

ugcccacgga agagagcaau aucacgaugc aaaucaugcg cauaaaaccg caccaggggc      960

aacacauagg ggagaugucg uuccuacaac acaacaaaug cgaaugccga cccaagaaag     1020

aucgagcacg ccaggaaaag aaaucaguca ggggcaaagg aaagggccag aaaagaaaaa     1080

gaaagaaaag ccgguacaaa agcuggagcg uauacguggg cgcgcgaugc ugccuaaugc     1140

cguggagccu accgggaccg cacccaugcg gacccugcag cgagagaaga aaacaccuau     1200

ucguacagga cccgcagaca ugcaaaugcu cgugcaagaa cacagauucg cgaugcaaag     1260

cacgacagcu cgagcucaau gaaaggacau gcagauguga caaaccccga cgcuagggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  7053
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt8)

<400>  7053
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc ucuccugggu ccacuggucc cuagcccucc      120

uacuauaccu ccaccacgcc aaauggagcc aagccgcccc cauggccgag ggcggcggac      180

aaaaccacca cgaagucgua aaauucaugg acguauacca acgaagcuac ugccacccca      240

ucgaaacccu cguagacaua uuccaagaau accccgacga aaucgaauac aucuucaaac      300

caagcugcgu accccuaaug cgaugcggcg gcugcugcaa cgacgaaggc cucgaaugcg      360

uacccaccga agaaagcaac aucacaaugc aaaucaugag aaucaaaccc caccaaggcc      420

aacacauagg cgaaaugucc uuccuccaac acaacaagug cgaaugccgc cccaaaaaag      480

accgcgcccg ccaagaaaag aaauccgucc guggaaaagg caaaggccaa aaacgaaaac      540

gaaaaaaaag ccgcuacaaa uccuggagcg ucuacguagg cgcccgaugc ugccuaaugc      600

cauggucccu ccccggcccc caccccugcg gccccugcuc cgaacgccga aaacaccucu      660

ucguccaaga cccacaaacc ugcaaaugcu ccugcaaaaa cacagacuca cgcugcaaag      720

caagacaacu cgaacuaaac gaacgcaccu gccgcuguga caaaccacga cgauaaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  7054
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt8)

<400>  7054
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaccacuac uccgccgacu acuccucgcc gcccuccucc      120

aacucgcccc cgcccaagcc cccgucagcc aacccgacgc cccaggccac caacgcaaag      180

ucgucuccug gaucgacguu uacacucgcg caacaugcca accccgcgaa guagucgucc      240

cacucaccgu cgaacuaaug ggcaccgucg ccaaacaacu cguccccuca ugcgucaccg      300

uccaacgcug cggaggaugc ugccccgacg acggccuaga augcguccca accggccaac      360

accaaguacg caugcaaaua cucaugaucc gauaccccuc aucccaacua ggcgagaugu      420

cccucgaaga acacucccaa ugcgaaugcc gacccaaaaa aaaagacucc gccgucaaac      480

ccgaccgagc cgccacaccc caccaccgcc cacaaccccg cuccguccca ggcugggacu      540

cagcccccgg cgcaccauca cccgccgaca ucacccaccc cacacccgca cccggccccu      600

ccgcccacgc cgcccccuca accaccuccg cacuaacccc cggccccgcc gccgccgccg      660

ccgacgccgc cgcaucauca guagcaaaag gcggagcaua aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  7055
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt8)

<400>  7055
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuccucg gauucuucuc aguagccugc ucccuucugg      120

ccgcagcccu ccuccccggc ccgcgcgaag cccccgccgc cgccgcagcc uucgaauccg      180

gccuagaccu gagcgacgcc gagcccgacg caggagaagc caccgccuau gccuccaaag      240

accucgaaga acaauugcgc ucggucucgu cagucgacga acucaugacc guccucuacc      300

cagaauacug gaaaauguau aaaugccaac uccgcaaagg uggcuggcaa cacaaccggg      360

aacaagccaa ccucaacagc cgaacagaag aaacaaucaa auucgccgca gcccacuaca      420

acacagaaau ccucaaaucc auagacaacg aauggcgcaa aacccaaugc augccccgcg      480

aagugugcau cgacguaggc aaagaguucg gcgucgccac aaacacauuc uucaaaccac      540

cgugcgucuc cgucuaccgc uguggcggau gcugcaacuc ggaaggacua caaugcauga      600

acacguccac cuccuaccuc uccaaaaccc ucuucgaaau aaccguacca cuaucccagg      660

guccaaaacc cguaacaaua uccuucgcaa accauacuuc cugccgaugc auguccaaac      720

uugacgucua cagacaggua cacagcauaa uccggcguuc ccuacccgcu acccuaccac      780

aaugccaagc agccaauaaa accuguccaa caaacuacau guggaacaac cacaucuguc      840

gcugccucgc ccaagaagac uucauguucu ccucagacgc cggcgacgac ucaacagacg      900

gcuuccacga caucuguggc ccaaacaaag aacuugauga agaaacaugc caaugcgucu      960

gccgagccgg acuccgaccc gcaagcugcg gcccccauaa agaacuagac cggaacucau     1020

gccaaugcgu auguaaaaau aaacuauucc ccucccaaug cggcgccaac cgggaguucg     1080

acgaaaauac cugccaaugc guaugcaaac gcacuugccc acgcaaccaa ccccuaaacc     1140

ccggcaaaug cgccugcgaa ugcaccgaau cgccccaaaa augccuacuc aaaggcaaga     1200

aauuccacca ccaaaccugc uccuguuacc gccgacccug caccaaccgc caaaaagccu     1260

gcgaacccgg uuucucauac ucagaagagg ucugccgaug cguccccagc uauuggaaac     1320

gcccacaaau guccuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  7056
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt8)

<400>  7056
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uaccgugaau gggucgucgu caacguauuc augaugcuau      120

acguucaacu cguccaagga uccucaaaug aacacggccc agucaaacgc agcucccaau      180

ccacacucga acgcuccgaa caacaaaucc gcgccgccuc cucccucgaa gaacuacuuc      240

gcaucaccca uucagaagac uggaaacuau ggcgaugccg ccuccgccuc aaaucauuua      300

ccucaaugga cagccgcuca gccucccacc gcuccacacg cuucgcggcc acuuuuuacg      360

acauagaaac cuuaaaaguc auagaugaag aauggcaacg cacacaaugc ucccccagag      420

aaaccugcgu cgaagucgcc uccgaacucg gcaaaucaac caacaccuuc uucaaacccc      480

caugcgucaa cguauuccgu ugcggaggcu gcugcaacga ggaaucauua aucugcauga      540

acacaagcac auccuacauc uccaaacaac ucuucgaaau cucuguaccc cucaccuccg      600

uccccgaauu aguaccuguc aaagucgcaa accacacagg augcaagugc cucccuaccg      660

caccccgcca ccccuacucc auaauccggc gauccaucca aauccccgaa gaagaccgau      720

gcucacacuc aaagaaacuc ugccccaucg acaugcucug ggacuccaac aaaugcaaau      780

gcguccucca agaagaaaac ccccuagccg gcaccgagga ccacucccac cuacaagaac      840

cagcccucug cggcccccac augauguucg acgaagaccg augcgaaugc gucugcaaaa      900

cccccugccc caaagaccuc auccaacacc ccaaaaacug cuccugcuuc gaaugcaaag      960

aaucccuaga aaccugcugc caaaaacaca aacuauucca cccagauacc ugcucaugcg     1020

aagaccgcug ccccuuccac acacgccccu gcgccuccgg caaaaccgcc ugcgccaaac     1080

acugccgauu ccccaaagaa aaacgcgccg cccaaggacc ccacucccgc aaaaaccccu     1140

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  7057
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt9)

<400>  7057
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg aaaccggcuu cgaacacucc ggccucuggg      120

ucuccguccu cgccggccuc cuccuaggcg ccugccaagc acaccccaua cccgauucuu      180

ccccacuacu ccaauucggc ggccaagucc gccaacgcua ccucuacaca gacgacgccc      240

aacaaacaga agcccaccua gaaauccgag aagacggcac agucggaggc gccgccgacc      300

aaucacccga aucccuccua caacuaaaag cccucaaacc cggcgucauc caaauccucg      360

gcgucaaaac cagccgauuc cucugccaac gccccgacgg cgcccucuac ggaucccuac      420

acuucgaccc agaagccugc uccuuccgcg aacuccuccu agaagacggc uacaacgucu      480

accaaucaga agcccacggc cucccccucc accuccccgg caacaaauca ccacaccgcg      540

acccagcccc acgcggcccc gcccgcuucc uuccccuccc cggccuccca cccgcacucc      600

ccgaaccccc aggcauccuc gcaccccaac ccccagacgu cggcuccuca gacccccucu      660

ccauggucgg ccccucucaa ggcagauccc cauccuacgc cuccuaagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  7058
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt9)

<400>  7058
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuccuucc cuccccuccu acuacuccuc uucuggggcg      120

uugucuccca cuccuucccc gcgacccuag aaacacagga acaagacguu gaccucgucc      180

aaaaauaccu agaaaaauac uacaaccuca aaaacgacgg acgccaagua gaaaaacgac      240

gcaacuccgg ccccgucguc gaaaaacuca aacagaugca agaguucuuc ggccucaagg      300

ucaccggcaa acccgacgcc gaaacacuaa aaguaaugaa acaaccccgc ugcggcguac      360

ccgacgucgc ccaauucgua cucaccgaag guaacccacg cugggaacaa acccaccuca      420

cuuaccggau cgaaaacuac acccccgacc ucccccgcgc cgacgucgac caugccaucg      480

aaaaagccuu ccaacucugg ucaaacguca caccccucac cuucaccaaa gucucugaag      540

gccaagcaga caucaugaua ucauucguac gaggcgacca ccgagacaac ucccccuucg      600

acggcccggg aggcaaccug gcacacgccu uccaaccagg uccaggaauc ggcggcgacg      660

cacacuuuga cgaggacgag cgauggacca acaacuuccg agaauacaac cuccaccgcg      720

ucgcagccca cgagcucggc cacucacugg gacucucaca cuccaccgau aucggagcac      780

ucauguaucc cucuuacacu uucuccggcg acguacaacu agcccaagac gacauagacg      840

gaauccaagc aaucuacgga cgcucccaga accccgucca gcccaucgga ccucaaacac      900

caaaagccug cgacuccaaa cuaacauucg acgccaucac aaccauacga ggcgaaguca      960

uguucuucaa agacagauuc uacaugcgca caaacccuuu cuaucccgaa gucgagcuca     1020

acuucaucuc cgucuucugg ccccaacucc ccaacggccu ugaagcagcc uacgaguucg     1080

ccgaccgcga cgaaguccga uucuucaaag gaaacaaaua cugggccguc caaggccaaa     1140

acguccuaca uggcuacccc aaagacauau acuccuccuu cggcuuccca agaaccguca     1200

aacacaucga cgcagcacuc uccgaggaaa acaccggaaa aaccuacuuc uucgucgcaa     1260

acaaauacug gcgcuacgac gaauacaagc gcucaaugga ccccggcuau ccaaaaauga     1320

ucgcacacga cuuccccggc aucggucaca aagucgaugc uguuuucaug aaagacggcu     1380

ucuucuacuu cuuccacgga acccgccaau acaaauuuga cccaaaaacc aaacgcaucc     1440

ucacacuaca aaaagccaac agcugguuca acugccgcaa aaacuaagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  7059
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt9)

<400>  7059
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuccuucc caccccuacu ccuccuacuc uucuggggcg      120

uagucuccca cucauucgua cucaccgaag gcaacccccg augggaacaa acccaccuca      180

ccuaccgcau agaaaacuac acccccgacc ucccccgcgc cgacguagac cacgccaucg      240

aaaaagccuu ccaacucugg uccaacguaa caccccucac cuucaccaaa gucuccgaag      300

gccaagcaga cauaaugaua ucauucgucc gcggcgacca ccgagacaac ucacccuucg      360

acggccccgg cggcaacuua gcccacgccu uccagcccgg cccaggcaua ggcggagacg      420

cacacuucga ugaagacgaa cgcuggacca acaacuuccg cgaauacaac cuccaccgcg      480

ucgcagccca cgaacucggc cacucccuug gacucucaca cuccaccgac aucggagccc      540

uaauguaccc aucauacaca uucucaggcg acguacaacu cgcccaagac gacaucgacg      600

gcauacaagc aaucuauggc cgcucacaga acccaguaca accaaucggc ccccaaaccc      660

ccaaagccug cgacuccaaa cucaccuucg acgcaauaac cacaauucga ggagaaguca      720

uguucuucaa agaccgauuc uacaugcgca ccaaccccuu cuaccccgaa guagaacuca      780

acuucauauc cgucuucugg ccucaacuac ccaacggccu cgaagcagca uacgaguucg      840

ccgaccgaga cgaaguccga uucuucaaag gcaacaaaua cugggccguc caaggccaaa      900

acguccuaca cggcuaccca aaagacaucu acucuuccuu cggcuuccca cgaacaguaa      960

aacacauaga cgcagcucuc ucagaagaaa acaccggcaa aacuuacuuc uucguagcaa     1020

acaaauacug gcgcuacgac gaauacaaac gcucuaugga ccccggauac cccaaaauga     1080

uagcucacga cuuccccggc auaggucaca aagucgacgc aguauucaug aaagacggcu     1140

ucuucuacuu cuuccacggc acccgccaau acaaauuuga ccccaaaacc aaacgcaucc     1200

ucacccuuca aaaagccaac uccugguuua acugucgcaa aaacuaagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  7060
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt9)

<400>  7060
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaagaaca uccuaaagau acucauggac agcuacagca      120

aagaaucgaa aauccaaacc guucgucgag uaaccuccgu aagccuccua gccguauauc      180

ugaccaugaa cacgagcagc cucguacuag ccaaacccau agaaaacacc aacgauaccu      240

caaucaaaaa cguagaaaaa cugaggaacg cacccaauga agaaaacuca aagaaaguug      300

aagacagcaa aaaugacaag gucgaacacg ucaaaaacau cgaagaagca aaaguagagc      360

aaguagcccc cgagguaaaa agcaaaagca cgcucagauc agcaagcauu gccaacacaa      420

acagcgaaaa auacgacuuc gaauaccuaa acggucuaag cuauaccgaa cugacgaacu      480

uaauaaagaa caucaaaugg aaccaaauaa acggccuauu caacuacucc acaggcagcc      540

aaaaauucuu cggggacaaa aacagaguac aggcaauaau caacgcgcuc caggaauccg      600

gccguaccua cacggcgaac gacaugaagg ggaucgaaac auucaccgaa guacuccgug      660

ccggcuucua ccuuggguau uacaaugacg gacucagcua ccucaacgac cgcaacuuuc      720

aggacaagug cauccccgca augaucgcaa uccaaaagaa cccuaauuuc aaauuaggaa      780

cagccguaca ggacgaggua aucacgagcc ugggcaaauu aaucggcaac gccucugcga      840

acgcagaggu cgucaacaac ugugugccag uccucaagca guuccgggag aaccugaauc      900

aauacgcacc cgacuacgua aagggcacug ccgucaacga acucauaaaa ggcauagagu      960

ucgacuucuc aggcgccgcc uacgaaaaag acguuaaaac gaugcccugg uacggaaaaa     1020

uagaccccuu cauaaacgaa uuaaaagccu uaggccucua cggcaacauc accagcgcaa     1080

cggaaugggc cucagacgua gguaucuacu aucuuuccaa auucggauua uacagcacca     1140

accgcaacga cauaguacaa ucccuagaga aagccgucga uauguacaaa uacggaaaaa     1200

uagcguucgu agccauggaa cgaaucaccu gggacuacga cggcaucggc ucaaacggca     1260

agaaagucga ccacgacaaa uuccuggacg acgccgaaaa acacuaucuc cccaaaaccu     1320

acacauucga caacgggacg uucauaaucc gcgcgggcga caaaguaucc gaagagaaaa     1380

ucaaacgccu auacugggcc uccagagaag uuaaaagcca auuucaccgg guggugggga     1440

acgacaaagc ccuagaaguc ggaaacgccg augacguccu cacaaugaaa aucuucaaua     1500

gucccgaaga auacaaauuc aacaccaaca uaaacggcgu uagcaccgac aaugggggcc     1560

uguacaucga accccggggc acauucuaca ccuacgaaag aacgccucaa caaucuaucu     1620

ucagucugga ggaguuguuc cgccacgaau acacccacua ccuacaagca cguuaccucg     1680

ucgacggccu auggggccag ggacccuuuu acgaaaagaa caggcuaacc ugguucgacg     1740

agggcacagc cgaguucuuc gccgggagca cccgcacauc cggaguacug cccaggaaaa     1800

gcauccucgg cuaccuugcc aaagauaaag uugaccaucg cuacucacug aagaagaccc     1860

uuaacagcgg auaugacgau agcgacugga uguucuacaa cuauggguuc gcgguagcac     1920

acuaccuaua ugaaaaagac augcccacuu ucaucaaaau gaauaaggca auccucaaca     1980

ccgacgucaa auccuacgac gaaaucauua agaaacugag cgacgacgca aacaagaaca     2040

ccgaguacca gaaccacauc caggagcuag ccgacaagua ccagggggca ggaauccccc     2100

uaguaucaga cgacuaccuc aaagaucacg gcuacaagaa agcgagcgaa guauacuccg     2160

aaauaucgaa ggcagcaagc cucacgaaca caagcgugac agccgaaaaa ucacaauacu     2220

ucaacaccuu cacucuccgg gguaccuaca caggcgagac cuccaaggga gaauuuaaag     2280

acugggacga aaugagcaaa aagcucgacg gcacccucga aucacucgcc aaaaacuccu     2340

gguccggcua caagacauua acugcauacu ucacuaauua ccgcgucacc agcgacaaca     2400

aaguccaaua cgacgucguu uuccacgggg uacuaaccga uaacgcagac aucuccaaca     2460

acaaagcacc uaucgcaaaa gucacgggac cauccacugg ggccguugga cgcaauauug     2520

aguucucagg uaaagacagc aaagacgagg acggcaaaau cgucagcuac gacugggauu     2580

ucggagacgg cgcgacauca cgaggcaaaa acagcgucca cgcauauaag aaagccggca     2640

ccuacaacgu uacacuaaag gucacagacg acaaaggagc aacagcgaca gagucauuca     2700

caauagagau caaaaacgag gacacgacga caccuaucac aaaagaaaug gaaccgaacg     2760

acgacaucaa agaagccaac ggcccaauag ucgaaggagu aaccguuaaa ggcgaccuca     2820

acggcucaga ugacgccgau accuucuacu ucgacgucaa ggaagacggg gacguaacaa     2880

uugaacuacc auacucaggg ucaagcaauu ucacauggcu cgucuacaaa gaaggcgacg     2940

aucagaacca uauagcauca ggcauagaca aaaacaacuc gaaagugggc accuuuaaaa     3000

gcacaaaagg ccgccacuac guguucauau acaaacacga cagcgccucg aacaucucuu     3060

acucacuaaa caucaagggc cuaggaaacg agaagcugaa agaaaaagaa aacaacgacu     3120

cuucagauaa ggccaccguc auucccaacu ucaacacaac aaugcaaggc ucgcugcucg     3180

gcgacgacuc cagagacuau uacuccuucg agguaaaaga agaaggagaa gucaacaucg     3240

aauuggacaa gaaagacgag uucgggguga cauggacccu ucacccggaa uccaacauaa     3300

acgacaggau aaccuacggg caaguagaug gaaacaaagu gucgaacaaa gucaagcucc     3360

gacccggcaa auacuacuug cuagucuaca aauacagcgg cucuggcaac uacgaacuac     3420

gaguaaacaa auagggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  7061
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt9)

<400>  7061
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguga cuuucauuuc ccugcuguuc cucuucagca      120

gcgccuacuc caucgcaaac acaaacagcg aaaaauacga cuucgaauac cugaacggac      180

ucaguuacac cgaacucaca aaccucauca agaacaucaa guggaaccaa auaaacggcc      240

ucuucaacua cucgaccggc ucccaaaagu ucuucgggga uaagaaccgc guccaagcca      300

uuaucaacgc ccuccaagaa agcgggcgca cauacaccgc caacgacaug aagggcauag      360

aaacauuuac agaagugcua cgcgcgggcu ucuaccucgg cuauuacaac gacggacuca      420

gcuaccuaaa cgaccgaaac uuccaggaca agugcauacc ggcaaugaua gccauccaga      480

aaaaucccaa cuuuaaacuc ggaacugccg ugcaagacga aguaaucacc ucgcucggaa      540

aacuaaucgg caacgccuca gccaaugccg aaguagucaa uaacugcguc cccgucuuaa      600

agcaauuccg agagaacuug aaccaauacg caccagacua cgucaagggc accgccguaa      660

acgaguuaau caaagggaua gaguucgacu ucucgggagc cgcauaugaa aaagacguca      720

aaaccaugcc augguacggc aaaaucgacc ccuucauaaa cgaacucaaa gcccuuggcc      780

uauacggcaa cauaacaagc gcgacagaau gggccagcga cguaggcauc uacuaccuau      840

caaaguucgg acucuacagc accaaccgga acgacauagu ccaaagccuc gaaaaagcag      900

uagacaugua caaauacggc aaaauagccu ucgucgcaau ggagcgcaua acaugggauu      960

acgacgggau cggcaguaau gguaagaaag uagaccauga caaguuccuc gacgacgcag     1020

aaaaacacua ccuaccuaag acauacaccu ucgacaacgg aaccuucaua auccgcgcag     1080

gcgacaaagu uagugaggag aaaaucaaaa gacuauacug ggcaucaaga gaagucaaau     1140

cacaauucca ccgcguaguc ggcaacgaca aagcccucga aguggggaac gccgacgacg     1200

uccuaacaau gaaaaucuuc aacagccccg aagaauacaa auucaauacu aauauaaacg     1260

gaguaagcac agacaacggc ggccuauaua ucgaaccccg cgggacuuuc uauaccuacg     1320

aaaggacgcc gcaacaaucc auauucucac uagaagaacu auuccgccac gaauacaccc     1380

acuaccucca ggcaagauac cuagucgacg gccuaugggg ucagggccca uucuacgaaa     1440

agaaccgccu aaccugguuc gacgagggaa cagccgaauu uuucgccgga uccacccgca     1500

caagcggagu ccugccccgc aaaucaauac ucggguaccu agcgaaagac aaaguggacc     1560

accgauacag ccuaaagaaa acacucaacu ccggauacga ugacagcgac uggauguucu     1620

acaacuacgg auucgccguc gcacacuacc uauacgagaa agacaugccc acuuucauca     1680

aaaugaacaa agcgauacuc aacaccgacg ucaaaagcua cgacgagauc aucaagaaac     1740

uguccgacga cgcaaauaaa aacaccgaau accagaacca cauucaggaa cucgccgaca     1800

aauaccaagg agccggcauc ccacucguca gcgacgacua ccucaaagac cacggguaca     1860

aaaaggcguc cgaaguauau ucugagauca gcaaagccgc aucccugacc aacacaucag     1920

ucacagcaga gaaaucucag uacuucaaca cauucacgcu ccgggggacc uacacaggcg     1980

aaacuagcaa aggggaguuc aaggacuggg acgagaugag caagaaacug gauggcacac     2040

ucgagagucu cgcgaaaaac uccuggucgg gcuacaaaac gcuuacagca uauuucacca     2100

acuaccgcgu caccucagac aacaaagucc aauacgacgu cguguuccac ggagugcuca     2160

ccgacaacgc cgacaucucc aacaacaagg caccuaucgc aaaggugacc ggccccucaa     2220

caggcgcggu uggacggaac aucgaguucu ccgggaaaga caguaaggac gaggacggca     2280

aaauaguaag cuacgacugg gacuucggag acggggcgac cucccgaggc aagaacagcg     2340

uccacgccua caagaaagcc ggcacauaca acgugacacu uaaaguuacc gacgacaaag     2400

gagccaccgc cacggagucc uuuaccaucg agaucaaaaa cgaagacacc acaaccccaa     2460

uaaccaaaga aauggaaccu aacgacgaca uuaaggaggc aaacggccca auaguagaag     2520

gaguuacggu caagggugac cucaacgguu ccgaugacgc agacaccuuc uacuucgacg     2580

ucaaagaaga cggggaugua accaucgaac uacccuacuc cggauccuca aauuucacuu     2640

ggcuaguaua caaggagggc gacgaccaaa accacauagc cucggggaua gacaaaaaca     2700

acucuaaagu aggaaccuuu aaguccacaa agggacggca cuacgucuuu aucuacaagc     2760

acgacuccgc uuccaacaua ucguacucgu uaaacaucaa aggacuagga aacgaaaaac     2820

ucaaagagaa agaaaacaac gacucaucgg acaaagcgac aguaauacca aacuucaaca     2880

ccacgaugca gggcucccua uugggagaug acagccgaga cuacuacucg uuugaaguaa     2940

aagaggaagg cgaagucaac aucgaacuag auaagaaaga cgaguucgga guuacgugga     3000

cccuccaccc cgagagcaac aucaaugacc gaauuaccua uggccagguc gacgguaaca     3060

aaguaucuaa uaaagucaaa cuccgcccag gcaaauacua ccuccucguc uacaaguaca     3120

gcgguagcgg caacuacgaa cuacgcguga auaaauaagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  7062
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt9)

<400>  7062
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga cauucaucuc ccuacuguuc uuauuuaguu      120

ccgccuauag uaugaaaaag aacauucuca aaauccucau ggacagcuac agcaaagaga      180

gcaagaucca gaccgugcgu cgaguaacca gcgucagcuu acuagcggua uaccuaacca      240

ugaacacauc cagccuaguc cuggcaaaac ccaucgaaaa caccaaugac acuuccauca      300

agaacgucga gaagcuacga aacgcaccaa acgaagagaa uagcaagaaa guugaagauu      360

ccaaaaauga caaaguagag cacgucaaaa acaucgaaga agcaaaaguc gaacaaguag      420

ccccggaagu caaauccaag agcacgcucc gcuccgccag uagacggcgc aggaaacgca      480

ucgcaaacac aaacuccgag aaauacgacu ucgaauacuu gaacggauua agcuacacgg      540

agcuaaccaa ccucaucaaa aauauaaaau ggaaccaaau aaacggccua uucaacuaua      600

gcaccggguc ccagaaauuc uucggagaua agaaccgcgu acaagcuauc aucaaugccc      660

ugcaggaauc cggccgcaca uacacggcca acgacaugaa agguauagaa acauucacag      720

aagugcuaag ggccggcuuc uaccucggcu acuacaacga cgggcuauca uaccuaaaug      780

acagaaauuu ucaggacaaa ugcauaccgg cuaugaucgc gauacagaaa aacccgaacu      840

ucaagcuagg cacggccgua caagacgaag ucaucaccuc cuugggaaaa cucauaggca      900

acgccuccgc gaacgccgaa gucgucaaca acuguguacc cguccuaaaa caguuuagag      960

agaaccuaaa ccaguacgcu ccggacuacg ucaaagggac agcagugaau gaacugauua     1020

agggaauaga guucgacuuc ucaggcgcug ccuacgaaaa ggacgugaaa accaugcccu     1080

gguacggcaa gaucgaccca uucaucaacg aauuaaaagc acucggccua uauggcaaca     1140

uaaccuccgc caccgaaugg gcaucggacg ucggaauaua cuaccucagu aaauuuggac     1200

uguauagcac caacagaaac gacaucgucc aaagccucga gaaagcaguc gacauguaca     1260

aauacggcaa aauagccuuc guggcaaugg aaaggaucac augggacuac gacggcaucg     1320

gguccaacgg aaagaaagua gaccacgaca aauuucuuga cgacgccgag aaacacuacc     1380

uaccaaaaac uuacaccuuc gacaacggca ccuucauaau cagagcagga gacaaaguca     1440

gcgaagagaa aaucaaacgg cuuuacuggg ccucacguga agugaaaagc caguuccacc     1500

gcgucguggg aaaugacaag gcauuggaag uagggaacgc ggacgacguc cuaacaauga     1560

aaauauucaa cagcccagaa gaauacaaau ucaacacuaa cauaaaugga gucuccaccg     1620

acaacggcgg ccucuacaua gaaccaaggg gcaccuuuua cacauacgaa cgcacaccuc     1680

agcaaagcau auuuucacua gaagaacucu uccgucacga auacacccac uaccuccagg     1740

cuagauaccu cguugacgga cuguggggcc agggccccuu uuaugagaaa aaccgccuca     1800

cgugguucga cgaaggcaca gccgaguucu ucgccggcag cacacgaacc agcggcguac     1860

uaccacgaaa aucgauccuc ggcuaccugg caaaagacaa agucgaucau agguacagcc     1920

ucaaaaagac acuaaacagc ggauaugacg acucugacug gauguuuuac aacuacgggu     1980

ucgccgucgc acacuaccuc uacgaaaagg acaugcccac auucaucaaa augaacaagg     2040

cgauccuaaa cacugacgua aaaagcuacg acgaaauaau aaagaagcua agcgacgaug     2100

ccaacaagaa cacagaguac caaaaccaca uucaggaacu ugccgacaaa uaccagggag     2160

ccggaauccc gcucguaucc gacgacuacc uaaaagacca cggauacaaa aaggcauccg     2220

aagucuacag cgaaauaagc aaggccgcgu cacuaacaaa cacgucaguc accgcagaga     2280

aaucccaaua cuucaacacc uuuacacuga gagggacaua caccggcgaa accucaaaag     2340

gagaguucaa agacugggac gaaaugucca agaaacuaga cggaacacuc gaaucgcuag     2400

cuaaaaacuc cuggagcgga uacaaaaccc ucacggcuua uuucaccaac uaccgcguca     2460

cgagcgacaa caagguacaa uaugacguug ucuuccacgg cguccucacg gacaacgccg     2520

acaucucaaa caauaaggcc cccauagcaa aaguaacagg accauccacc ggcgcagucg     2580

gccgaaacau agaguucuca ggcaaagauu ccaaagacga agacgggaaa aucguuaguu     2640

acgauuggga cuucggcgac ggcgccaccu cgcgagguaa gaacuccgug cacgcauaca     2700

aaaaggccgg aaccuacaac guuacccuaa aggugacaga cgacaaagga gcgacggcga     2760

cagaaucuuu cacaaucgaa aucaaaaacg aagacacuac aacacccauc acgaaagaaa     2820

uggagcccaa cgacgacauc aaggaagcaa acgggccgau cguugaagga guaaccguca     2880

aaggagaccu caacgggagc gacgacgcag acaccuucua cuucgauguc aaagaggacg     2940

gggacguaac aaucgagcuc cccuacucag gaagcagcaa cuucacaugg cuaguguaca     3000

aggagggcga cgaccagaac cacauagcgu ccggcaucga caaaaacaac ucaaaaguag     3060

gcaccuucaa aaguaccaaa ggccgccacu acguuuucau cuacaagcac gacuccgccu     3120

ccaacauaag cuacucgcua aacaucaagg gcuuaggcaa cgaaaaacug aaagaaaaag     3180

aaaacaacga cucaucugac aaggccaccg uaauacccaa uuucaacaca accaugcagg     3240

gcucacugcu cggagacgac ucacgagauu acuacuccuu ugaaguaaaa gaagaaggcg     3300

aaguaaacau cgaauuggau aagaaagacg aguucggcgu gacguggaca cuucacccag     3360

aaucaaacau caacgacagg auaaccuaug ggcaaguaga cggcaacaaa guaucuaaca     3420

aggucaagcu ccgccccggc aaguacuacc ugcucgucua caaauacagc ggaucuggaa     3480

acuaugaacu ccgcguaaac aaauaaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  7063
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt9)

<400>  7063
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuca aaaucauacu gaaccgcgga aaaaccauga      120

agagaaagug ccuauccaaa agguuaaugc ucgccauaac cauggccacg auauucacag      180

ugaacucgac ccucccgauu uacgccgccg uagacaaaaa caacgcgacc gccgcgguac      240

agaacgaguc caaacgguac acgguauccu aucucaagac ccucaacuac uacgacuugg      300

ucgaccuucu cgucaaaaca gagauagaaa accuucccga ucuauuccaa uacucuagcg      360

acgccaaaga guucuacgga aacaaaacaa gaaugucguu caucauggac gagaucggcc      420

gccgcgcucc ucaauacaca gaaauagacc acaaaggcau acccacccug gucgaggucg      480

uccgcgccgg cuucuaccua gguuuccaca acaaagaacu aaacgaaauc aacaagcgca      540

gcuucaaaga aagggucaua cccuccauac uggcuaucca gaaaaacccc aacuucaaau      600

ugggaaccga aguacaagac aaaauagucu cagccacagg ccugcucgca gguaacgaga      660

cugcaccacc ggaaguggua aauaacuuca ccccgauacu ccaagacugu aucaagaaca      720

ucgaccguua cgcccucgac gaucucaaaa gcaaagcacu cuucaacgug cucgcagcac      780

caacguauga uaucacugaa uaccugagag caaccaaaga aaaaccggag aacacccccu      840

gguacgggaa aaucgacggg uucauaaacg aauugaagaa acuggcccuu uacggcaaaa      900

uaaacgacaa uaacucaugg auaaucgaca acggaaucua ccacauagca ccccucggca      960

aacuccacag uaacaacaaa auagggaucg agacccuaac cgaagugaug aagguuuacc     1020

ccuaucucuc aaugcagcau cuccagagug cagaccaaau aaaaaggcau uacgacucaa     1080

aagacgccga gggcaacaag auaccucucg acaaguucaa gaaagagggc aaagaaaagu     1140

acugccccaa aaccuacacg uuugacgaug guaaagucau cauaaaggca ggagcacgag     1200

ucgaagaaga aaaagucaaa cgucuuuacu gggccagcaa ggaaguaaac agccaguucu     1260

uccgagucua cggcaucgac aaaccacucg aggaaggcaa cccggaugac auccucacaa     1320

uggugaucua caacagcccg gaggaguaca aacuuaacuc cgucuuguac ggcuaugaca     1380

ccaacaaugg cgggauguac aucgaaccag aaggaacuuu cuucaccuau gagcgcgaag     1440

cccaagaguc caccuauacc cucgaggaac ucuuccgaca cgaauacacu cauuacuuac     1500

aaggccgcua cgcaguaccc gggcaauggg gccgcaccaa gcuauacgac aaugacagac     1560

uaacuuggua cgaggaaggc ggagccgaac uauucgcagg cuccacacgc accucaggaa     1620

uacucccucg caaaagcaua guauccaaca uacacaacac cacccgaaac aacagauaua     1680

aacuaagcga caccguccac agcaaauacg gagcgagcuu cgaguucuac aacuacgccu     1740

gcauguuuau ggacuauaug uacaacaaag auaugggcau acucaacaaa cuuaacgacc     1800

uagcaaagaa caacgacguc gacggcuacg acaacuacau acgggaccuc agcucgaacu     1860

augcacuaaa cgacaaauac caagaccaca ugcaggaacg cauagacaac uacgaaaacc     1920

ucaccguacc cuucgucgca gacgacuacc uaguccgaca cgcguacaaa aaucccaacg     1980

aaaucuacuc cgaaaucagc gaagucgcca agcugaagga ugccaaaagc gaagugaaga     2040

aaucacaaua uuucucaacc uucacgcucc gcggcucaua cacagguggc gccuccaaag     2100

gaaaacuaga ggaucaaaaa gcaaugaaca aguucauaga cgacucccuc aaaaagcucg     2160

acacauacuc cugguccggc uacaaaacac uuaccgcgua cuucaccaac uacaaaguag     2220

acuccucgaa ucgaguaacc uacgacgucg uauuccacgg cuaccuucca aacgaaggcg     2280

acuccaaaaa cucccuaccc uacggaaaga uaaacggcac cuacaaaggu accgaaaagg     2340

agaaaaucaa auucuccagc gaagggucau uugacccaga cggaaaaauc gucuccuacg     2400

aaugggacuu cggagacgga aauaagucaa acgaagaaaa ccccgaacac agcuacgaca     2460

aagugggaac cuacaccgua aagcucaaag ugacagauga caaaggcgaa ucaaguguaa     2520

guacgaccac ugcugagaua aaagacuugu cggagaauaa acuucccgua aucuacaugc     2580

acguccccaa aucaggagca cuaaaccaga aagucguauu cuacggcaaa ggaaccuacg     2640

accccgacgg cucaauagcc ggauaucaau gggauuucgg ggacggaagc gacuuuucgu     2700

cggaacagaa ccccagccac guguacacga agaaagggga auacaccguc acccugcggg     2760

uaauggacag cucaggccaa auguccgaga aaacaaugaa aauaaaaauc accgaccccg     2820

ucuaccccau cggcacggaa aaagaaccca acaacuccaa agaaaccgca uccggcccaa     2880

ucgugcccgg cauacccguc uccggcacaa uagaaaauac cuccgaccaa gacuacuucu     2940

auuucgaugu caucaccccc ggagagguca aaaucgacau caacaaacug ggcuacggcg     3000

gagcaaccug gguagucuac gacgagaaca acaacgccgu caguuacgca accgacgacg     3060

ggcaaaaccu cagcggaaag uucaaagccg acaaaccagg aagauacuac auccaccuau     3120

acauguucaa uggcagcuac augcccuaca gaauuaauau cgagggaucc gugggccgcu     3180

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  7064
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt9)

<400>  7064
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacgaaaau gccuuagcaa acgccugaug cucgccauua      120

ccauggcgac aauauucacc gugaacagua cgcucccuau cuacgcagcc guagacaaaa      180

acaacgcaac cgcagccgua cagaacgagu ccaaacgcua caccgucucc uaucucaaga      240

cccuaaacua cuacgaccuu guagaccucc ucgugaagac cgaaaucgaa aaccuacccg      300

accucuucca auacuccagc gacgccaagg aguucuacgg aaacaaaacc cgaaugagcu      360

ucauaaugga cgaaaucggu cgccgcgcgc cccaauacac ggaaaucgac cauaaaggaa      420

ucccuaccuu agucgagguc guaagagcgg guuucuaccu aggauuccac aacaaagagc      480

uaaacgagau caacaaacgc uccuucaaag aacgcgugau ccccucuauc cuagccaucc      540

agaaaaaccc aaauuucaaa cucggcaccg aaguacaaga uaaaauagua agcgccaccg      600

gacuccucgc uggcaacgaa accgcacccc cagaaguagu gaauaacuuc acacccaucc      660

uccaagauug caucaaaaau auagaccgau acgcccugga cgauuuaaaa agcaaagcac      720

ucuucaacgu acucgcugca cccacauacg acaucacaga guacuugagg gcaacgaaag      780

agaaacccga aaacaccccc ugguacggaa aaauagacgg cuucaucaac gaacuaaaga      840

aauuggcgcu auaugggaaa aucaacgaca acaacaguug gauaaucgac aacggcaucu      900

aucacauagc accccucggc aaacuccaua gcaacaacaa aauaggcaua gaaacacuaa      960

cugaagucau gaaaguauac cccuaucuca gcaugcaaca ccuacaaucc gccgaccaaa     1020

ucaaacgcca cuacgacagc aaagacgcag aaggcaacaa aauaccccuc gacaaguuca     1080

agaaagaagg aaaagagaaa uacugcccca aaaccuacac cuucgacgac ggcaaaguaa     1140

ucaucaaggc cggagcacga guagaagaag agaaaguaaa acgacucuac ugggcgagca     1200

aagaagucaa uagccaauuc uuccgcguuu acgguaucga uaaaccgcuu gaagaaggca     1260

acccagauga cauccuaacg augguuaucu auaacagucc cgaagaauac aaacucaaca     1320

gcguccuuua uggguacgac accaauaacg gcgggaugua caucgaaccc gaggggaccu     1380

ucuucacaua cgaacgagaa gcccaagaau ccaccuacac acuagaagaa cucuuccgcc     1440

acgaauacac ccacuaucuu cagggcagau acgccguacc aggacaaugg gggaggacca     1500

aauuauacga caacgaccga cucacauggu acgaagaagg cggcgccgag uuauucgcug     1560

gaaguacucg aaccuccggc auccuucccc gaaaaagcau agucucgaac auccacaaca     1620

caacccguaa caaucgcuac aaacuauccg auacagucca cagcaaauau ggagcuagcu     1680

uugaguucua caacuaugcc ugcauguuca uggacuacau guacaacaag gacaugggca     1740

uccucaacaa acuaaacgac cuggcgaaaa acaacgacgu agacggcuac gacaacuaca     1800

uacgcgaucu uagcucuaac uacgcccuaa acgacaaaua ucaagaccau augcaggaac     1860

ggaucgauaa uuacgaaaau cucacaguac ccuucgucgc cgacgacuac cuaguccggc     1920

augcauacaa aaacccgaau gagauauacu ccgagaucuc agaagucgca aaacugaaag     1980

acgcaaaguc ggaaguuaaa aagagccaau acuucagcac auucacccuc cgcggaucuu     2040

acaccggcgg ggccuccaag gggaaacuug aggaccaaaa agcaaugaac aaauuuaucg     2100

acgacagccu caaaaagcuc gacaccuaca gcuggagcgg guacaaaaca cuuacggcau     2160

acuucaccaa uuacaaaguc gacucgagca aucgggucac cuacgacgug gucuuccacg     2220

gcuaccuacc gaacgaaggc gacagcaaaa acucacuacc guacggcaaa auaaacggca     2280

cguauaaagg gaccgaaaaa gaaaagauca aguucucauc agaaggcucc uucgacccag     2340

acggaaaaau agugagcuau gagugggauu ucggcgacgg gaacaaauca aacgaagaga     2400

acccggagca cagcuacgac aaagucggga ccuacaccgu caaacuaaaa gucaccgaug     2460

acaaaggcga guccucagua uccacgacca cggcugaaau caaagaccug agcgaaaaca     2520

agcucccagu cauauacaug cacgucccga aauccggcgc ccuaaaccag aaagucgucu     2580

ucuacggcaa aggcacuuac gacccagacg gcagcauagc aggauaccaa ugggacuucg     2640

gggacggcuc cgacuucuca ucagaacaga acccaucaca cgucuacacc aaaaagggcg     2700

aguacacagu uacacuccgc gugauggacu ccuccggaca aaugagcgag aaaacaauga     2760

aaauaaaaau aaccgacccg guauacccaa uaggcacgga aaaggaaccu aacaacagca     2820

aagaaacagc aucagguccc auuguacccg gcaucccagu cucaggaacc aucgaaaaca     2880

ccuccgacca agacuacuuc uacuucgaug uaauaacacc cggcgaagua aaaaucgaca     2940

ucaacaaacu cggguacggg ggagcaaccu gggucguaua cgaugaaaac aacaacgcug     3000

ucucauacgc aaccgacgac ggacagaacc ugagcggcaa guucaaagcc gacaaaccag     3060

ggagguacua cauacaccuc uacauguuca augguagcua caugccuuac cguauaaaua     3120

ucgaaggauc uguaggacga uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  7065
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt9)

<400>  7065
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguga ccuucauaag ccuucucuuc cucuucucau      120

ccgccuacag cguacaaaac gagucgaaaa gauacaccgu aucauaccuc aagacccuca      180

acuacuacga ucucgucgau cuauuaguca agacagaaau cgaaaaucua cccgaccuau      240

uccaguacuc aucggacgcc aaagaguucu acggcaacaa aacacgaaug agcuucauua      300

uggacgaaau agguagacga gcgccgcagu acacggaaau cgaccacaaa gggaucccca      360

ccuuagucga aguuguacgc gcgggcuucu accuaggauu ucacaacaaa gaacuuaacg      420

aaaucaacaa acgcaguuuc aaagaacgcg ucauccccag cauccuagcg auccagaaaa      480

accccaauuu uaaacucggc accgaaguac aggacaagau agugucagca acaggccugc      540

ucgccggaaa cgaaacggcc ccacccgaag uagucaauaa cuucacaccc auacugcagg      600

acugcaucaa aaauaucgac cgauacgcac ucgacgaccu caagagcaaa gcccucuuca      660

acgugcucgc cgccccaacc uacgacauaa ccgaauacuu gagggccaca aaagaaaaac      720

ccgaaaacac cccaugguac ggcaaaauug acggauucau caacgagcug aagaaacucg      780

cccucuacgg gaaaaucaau gacaacaaca gcuggaucau cgacaacggc aucuaccaca      840

uugccccgcu aggcaaacua cacuccaaca acaaaaucgg caucgaaacg cucacggaag      900

ucaugaaagu auauccauau cuauccaugc aacaccucca aucugccgac caaaucaaac      960

gccacuacga cagcaaggac gcggaaggaa acaaaauccc acucgacaag uuuaagaagg     1020

aaggcaaaga aaaauacugc ccuaaaaccu acacguucga ugacgggaaa guaauuauca     1080

aagccggcgc ccgagucgaa gaggaaaagg ugaaacgccu auacugggcc uccaaagagg     1140

uuaauucaca auuuuuccga gucuauggca ucgacaaacc acucgaggaa gguaaccccg     1200

acgauauccu caccauggua auauauaauu cgcccgagga auauaaacuc aacagcgucu     1260

uauacggcua cgacaccaac aacgguggca uguacaucga gccggaaggc accuucuuca     1320

ccuacgagcg ugaagcccaa gaauccacgu acacacuuga ggaacuauuc cgacaugaau     1380

acacccacua ccugcaaggc cgguacgcag uaccuggcca guggggccgc acuaaacucu     1440

acgacaacga ccgucucacc ugguacgaag aagguggagc cgaacucuuc gccggcucca     1500

cccgcaccag cggcauccua ccccgaaaau ccauagucuc gaacauucac aacacaaccc     1560

gaaauaaccg cuacaaacuc agcgacaccg uacacucaaa auacggagcc agcuucgagu     1620

ucuacaacua cgcgugcaug uucauggacu acauguacaa caaagauaug gggauucuaa     1680

acaaacuuaa cgaccucgcc aaaaauaacg acgucgacgg uuacgacaac uauauacgag     1740

aucuuucauc gaacuacgca cuaaacgaca aauaccagga ccacaugcaa gaacgcaucg     1800

acaacuacga aaaccucacc guccccuucg ucgcagacga uuaccucguc cgacacgcau     1860

acaagaaccc caacgaaaua uacucggaga ucagcgaagu cgccaagcuc aaagaugcaa     1920

aauccgaagu caaaaaguca caguacuuua gcacauucac acuccgcggg agcuacaccg     1980

gcggcgcguc caagggaaag cucgaagacc aaaaagccau gaacaaauuu auagacgacu     2040

cccucaagaa acucgacacc uacucgugga gcggcuacaa aacacuuacc gcauacuuca     2100

ccaacuacaa aguagacagc ucaaaucggg uaacuuacga cguagucuuc cacggcuacc     2160

uucccaauga aggagacagc aagaacucac ucccuuacgg caaaauaaau ggaacguaca     2220

agggcacgga aaaggagaaa aucaaauuca gcuccgaagg cuccuucgac cccgacggaa     2280

aaauaguauc auacgaaugg gacuucggcg acggcaacaa gaguaacgaa gaaaaucccg     2340

aacacucaua cgacaaaguc ggcacguaca ccgucaaacu aaaaguaaca gacgacaaag     2400

gcgaauccuc agugaguacg accaccgcag aaaucaaaga cuuaucagaa aacaaacucc     2460

ccguaauaua caugcacguc ccaaagagcg gggcacucaa ccaaaaaguc gucuucuacg     2520

gcaaaggaac cuacgacccu gacggaucca ucgccggcua ccagugggau uucggcgacg     2580

gaagcgacuu cucaucggag caaaacccaa gccacgucua cacgaaaaag ggagaauaca     2640

cagugacacu ccgaguaaug gacuccucag ggcagauguc cgagaaaacc augaaaauaa     2700

agaucaccga cccugucuac cccaucggaa ccgaaaagga gccuaacaau uccaaagaaa     2760

ccgccagcgg accaauagua cccgguaucc ccgucuccgg aaccaucgaa aacacgucag     2820

accaggacua cuucuacuuc gacgucauaa ccccgggcga aguaaaaauc gacaucaaca     2880

aacuaggcua cggcggagcc acaugggucg uauacgacga aaacaacaac gcgguaucuu     2940

acgcaacaga cgacggccaa aaccuaagcg gcaaguucaa agcagacaaa cccgggcgcu     3000

acuacaucca ccuguacaug uucaacggaa gcuacaugcc auacagaaua aauaucgaag     3060

gcuccguagg acguuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  7066
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt9)

<400>  7066
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguca ccuucaucuc ucuacuguuc cucuucucua      120

gcgcauauag caugaaacgg aaaugucuau ccaaacgccu gaugcuggcc auuacgaugg      180

ccaccaucuu caccgucaac ucuacccugc cgaucuacgc cgccguagac aagaacaacg      240

ccaccgccgc ucgccgccga agaaagaggg uccaaaacga aagcaaaaga uacacaguaa      300

gcuaccuuaa gacacucaac uacuacgacc ucguagaccu acucgucaag acagaaauug      360

agaaccuccc cgaccuauuc caauacagca gcgacgccaa agaguucuac ggcaacaaaa      420

cccgaauguc uuucauaaug gaugaaauag gacgcagagc gccccaauac acggaaaucg      480

aucacaaagg cauacccacc cuaguggaag ucguacgagc uggcuucuau cuggguuucc      540

acaacaaaga acugaacgaa auaaacaagc gcagcuucaa agaacgcgug auccccucaa      600

uacuggcuau ccagaaaaau cccaauuuca aacuagggac cgaaguccaa gacaagaucg      660

uguccgcgac aggacuccuc gccggcaacg aaaccgcccc gccggaaguc guuaacaacu      720

ucacgccaau acuacaagac ugcauuaaaa acaucgaccg auacgcccua gacgaucuga      780

aauccaaggc acuauucaac guucuggccg caccaacaua cgacaucaca gaguaccugc      840

gugccacaaa agaaaaacca gaaaauaccc ccugguacgg caaaaucgac ggauucauua      900

augaguugaa aaagcuagca cucuacggaa aaaucaacga caauaacagc uggaucaucg      960

acaacggcau uuaccacaua gcgccccucg gcaaacugca cuccaacaac aaaaucggua     1020

uagagacacu cacagaggug augaaaguuu acccauaccu aagcaugcaa caccuucaau     1080

ccgccgacca aaucaaacgc cacuacgacu ccaaagacgc ggaaggcaac aaaauacccc     1140

ucgacaaauu uaaaaaggag ggcaaagaaa aauacugccc aaagaccuac accuucgaug     1200

acggcaaagu aauaaucaaa gcaggagcca gagucgagga ggagaagguc aaaaggcuau     1260

acugggcauc uaaggaagug aacagccaau ucuuucgggu auacggaauc gacaagcccc     1320

uagaagaagg uaaccccgac gacauccuua caaugguaau auacaacagc ccggaagagu     1380

acaaacucaa caguguucua uacggauacg auacgaacaa cggaggcaug uacaucgaac     1440

cggagggcac cuucuucacc uacgagcgag aggcccaaga aagcacauac accuuagaag     1500

aacuguuccg acacgaauac acccauuacc uccaaggcag auacgcuguc cccggccaau     1560

ggggacgcac uaaacuauac gauaacgacc gccuaacaug guacgaagag gguggcgccg     1620

aacucuucgc cggcucaacg agaacgagcg gaauccugcc gcgcaaaagc aucgucagca     1680

acauacacaa cacaacgcga aacaaucguu acaaacucuc ggacacgguc cacucaaaau     1740

acggcgcguc auucgaguuc uacaacuacg ccugcauguu cauggauuac auguacaaua     1800

aggacauggg cauccuaaac aaacucaacg accucgcuaa aaacaacgac gucgacggcu     1860

acgacaacua uauccgagac cuaagcucga acuacgcacu caaugacaaa uaccaagacc     1920

acaugcaaga gcgcaucgac aacuacgaaa accuaacagu acccuucguu gcggacgacu     1980

aucucgucag gcacgcauac aagaacccaa acgagauaua cagcgaaauc agcgagguag     2040

ccaaacuuaa ggacgccaaa uccgaaguca agaaaucgca guacuucuca accuucacgc     2100

uacguggcag cuacaccggg ggagcaagca aaggaaaacu cgaggaccaa aaagcaauga     2160

acaaguuuau ugacgacagc cuaaagaaac uagauacaua uuccuggucc ggcuacaaaa     2220

cgcuaacggc auacuucacg aacuacaagg uugacucaag uaaccgcgua acauacgacg     2280

uaguuuucca cggauaccua ccaaaugaag gcgacuccaa aaacucgcug ccauacggaa     2340

aaaucaaugg cacauacaaa gggacagaga aggagaaaau caaauucagu ucagaaggau     2400

ccuucgaccc agacggcaaa aucguuucau augaauggga uuucggagac gggaacaaau     2460

caaacgaaga aaacccugag cacagcuacg acaaagucgg cacauauaca guaaagcuca     2520

aagucacgga cgacaagggc gagagcagcg uaagcacgac caccgcagaa aucaaggacc     2580

ucuccgaaaa uaaacuccca gucauauaca ugcacguacc aaaaucgggc gcccucaacc     2640

agaaaguagu guucuacgga aaaggcacau acgauccgga cggauccaua gcaggcuacc     2700

aaugggauuu cggagauggg agcgacuucu cgagcgaaca aaacccguca cacgucuaca     2760

cuaaaaaggg cgaguacacc guaacccuuc ggguaaugga cuccuccgga caaaugucug     2820

agaaaaccau gaaaaucaag auaaccgacc caguauaccc caucggcacc gaaaaagaac     2880

caaacaacuc caaagaaacu gccuccggcc ccaucguacc gggaauccca gucuccggca     2940

ccaucgaaaa caccagcgac caagauuacu ucuacuucga cguaaucacc cccggagaag     3000

ucaaaaucga caucaacaaa cugggcuacg gaggagcuac cuggguaguc uacgacgaaa     3060

acaacaacgc cgucaguuac gccaccgacg acgggcaaaa ccuguccggu aaauuuaagg     3120

ccgacaagcc agggcgauac uacauccacc uguauauguu uaacggaucc uauaugcccu     3180

accgaauaaa uaucgaagga aguguaggcc gcuaaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  7067
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt9)

<400>  7067
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacucuucgc augccuccuc ggcgcagccu      120

ucgccaugcc ccucccuccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacacc ccucaaaugg uaucaaucca ucagaccacc cuaccccucc uacggcuacg      240

aacccauggg cggcuggcuc caccaccaaa ucauccccgu ccucucacaa caacacccuc      300

ccacccacac ccuccaaccc caccaccaca uccccguagu ccccgcccaa caacccguca      360

ucccccaaca acccaugaug cccguccccg gccaacacuc aaugaccccc auccaacacc      420

accaacccaa ccucccacca cccgcccaac aacccuacca accccaaccc guccaacccc      480

aaccccacca acccaugcaa ccccaaccac ccguacaccc caugcaaccc cucccacccc      540

aaccaccccu accucccaug uuccccaugc aaccccuccc acccaugcuc cccgaccuca      600

cccucgaagc cuggcccucc accgacaaaa ccaaacgcga agaaguagac uaaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  7068
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt9)

<400>  7068
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuacccc cccacccagg ccaccccggc uacauaaacu      120

ucuccuacga aguacucaca ccccuaaaau gguaccaauc cauccgaccc cccuaccccu      180

cauacggcua cgaacccaug ggcggcuggu aaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  7069
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt9)

<400>  7069
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacauaaacu      120

ucucauacga aguccucacc ccccuaaaau gguaccaauc cauccgcccc ccccccaugc      180

uccccgaccu cacacucgaa gccuggcccu caaccgacaa aacaaaacgc gaagaagucg      240

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  7070
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt9)

<400>  7070
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccguaaugg ccccccgaac ccucguccuc cuacucucag      120

gagcccucgc ccucacccaa accugggcca ugccccuccc accccaccca ggccaccccg      180

gauacaucaa cuucuccuac gaaguacuca ccccccuaaa augguaccaa uccauccgcc      240

cccccuaccc cucauacggc uacgaaccca ugggcggaug guaaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  7071
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt9)

<400>  7071
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccguaaugg caccccgcac ccucguccua cuccuauccg      120

gcgcccucgc ccucacacaa accugggcca ugccccuccc accccacccc ggccaccccg      180

gcuacauaaa cuucuccuac gaaguccuca ccccacucaa augguaccaa uccauccgcc      240

caccacccau gcuacccgac cucacacucg aagccuggcc cuccaccgac aaaacaaaac      300

gcgaagaagu cgacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  7072
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt9)

<400>  7072
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuaguc ggcgccgccu      120

ucgccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccuaacacc ccuaaaaugg uaccaaucca ugauccgccc acccuacucc uccuacggcu      240

acgaacccau gggcggaugg cuccaccacc aaaucauccc cgucgucucc caacaacacc      300

cccucaccca cacccuccaa ucacaccacc acauccccgu aguccccgcc caacaacccc      360

gcguacgaca acaagcccuc augcccgucc ccggccaaca auccaugacc cccacccaac      420

accaccaacc caaccuccca cuccccgcac aacaacccuu ccaaccccaa cccguccaac      480

cccaacccca ccaaccaaug caaccccaac cacccgucca acccaugcaa ccccucuuac      540

cccaaccacc ccuaccaccc auguuccccc uccgcccccu accacccauc cuccccgacc      600

uccaccucga agccuggccc gccaccgaca aaacaaaaca agaagaaguc gacuaaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  7073
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt9)

<400>  7073
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuaccac cccacccagg ccaccccggc uacaucaacu      120

ucucauacga aguccucacc ccccuaaaau gguaccaauc aaugauccgc cccccauacu      180

cauccuacgg cuacgaaccc augggcggcu gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  7074
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt9)

<400>  7074
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccacccagg ccaccccggc uacaucaacu      120

ucuccuacga aguacucacc ccccuaaaau gguaccaauc caugauccgc ccccccccca      180

uacuccccga ccuccaccuc gaagccuggc ccgccacaga caaaaccaaa caagaagaag      240

uagacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  7075
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt9)

<400>  7075
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagucaugg caccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccuaacccaa accugggcaa ugccacuacc cccacacccc ggccaccccg      180

gcuacaucaa cuucucauac gaaguccuaa caccccucaa augguaccaa ucaaugaucc      240

gcccacccua cuccuccuac ggcuacgaac ccaugggcgg cugguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  7076
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt9)

<400>  7076
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg caccccgaac acucguccuc cuccucuccg      120

gcgcccucgc ccucacacaa acaugggcca ugccccuccc accccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca caccccuaaa augguaccaa uccaugaucc      240

gcccaccccc aauacucccc gaccuacacc ucgaagccug gcccgccacc gacaaaacca      300

aacaagaaga agucgacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  7077
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt9)

<400>  7077
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uacucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuaccaccc caccccggac accccggcua caucaacuuc uccuacgaag      180

uccuaacacc ccucaaaugg uaccaaaaua ugauacgcca ccccuacaca uccuacggcu      240

acgaacccau gggcggaugg cuccaccacc aaaucauccc cgucgucuca caacaaaccc      300

cacaauccca cgcccuccaa ccccaccacc acauccccau gguccccgcc caacaacccg      360

gcauccccca acaacccaug augccccucc ccggccaaca cuccaugacc cccacccaac      420

accaccaacc caaccuaccc cuacccgccc aacaacccuu ccaaccccaa cccguacaac      480

cccaacccca ccaaccccuu caaccccaau cucccaugca ccccauccaa ccccuccucc      540

cccaaccacc ccuuccaccc auguucucaa ugcaaucacu ccuccccgac cucccccucg      600

aagccuggcc cgccaccgac aaaaccaaac gagaagaagu cgacuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  7078
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt9)

<400>  7078
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuaccac cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccuaaca ccccuaaaau gguaccaaaa caugauccgc cacccauaca      180

ccucauacgg cuacgaacca augggcggcu gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  7079
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt9)

<400>  7079
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccucccac cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccuaaca ccccucaaau gguaccaaaa caugauccga caccccuccc      180

uacuccccga ccucccccua gaagcauggc ccgccaccga caaaaccaaa cgcgaagaag      240

ucgacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  7080
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt9)

<400>  7080
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg caccccgcac ccuaguccuc cuccucucag      120

gcgcccucgc acucacccaa acaugggcca ugccccuacc cccacacccc ggccacccag      180

gcuacaucaa cuucucauac gaaguccuca ccccacuaaa augguaccaa aacaugauac      240

gccaccccua caccucauac ggauacgaac ccaugggcgg cugguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  7081
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt9)

<400>  7081
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg caccccgcac ucucguccuc cuacucuccg      120

gcgcccuagc ccucacccaa accugggcca ugccccuacc cccacacccc ggccaccccg      180

gcuacaucaa cuucucauac gaaguccuca ccccacuaaa augguaccaa aacaugaucc      240

gccaucccuc acuccucccc gaccuccccc uagaagccug gcccgccaca gacaaaacca      300

aacgcgaaga agucgacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  7082
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt9)

<400>  7082
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uacucuucgc cugccuccuc ggcgcagccu      120

ucuccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc ucuuacaucc      180

gccaccccua caccuccuac ggcuacgaac ccaugggcgg cuggcuacac caccaaauca      240

uccccgucgu aucccaacaa accccacaau cacacgcucu ccaaccccac caccacaucc      300

ccaugguccc cgcccaacaa cccggcaucc cccaacaacc caugaugccc cuccccggcc      360

aacacuccau gacccccacc caacaccacc aacccaaccu cccccuccca gcccaacaac      420

ccuuccaacc ccaacccguc caaccccaac cacaccaacc acuacaacca caauccccca      480

ugcaccccau ccaaccacuc cucccccaac caccccuccc acccauguuc ucaaugcaau      540

cccuccuacc cgaccuuccc cuugaagccu ggcccgccac cgacaaaacc aaacgagaag      600

aagucgacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  7083
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt9)

<400>  7083
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuucgc augccuccua ggcgccuccc      120

ucgccaugcc ccucccaccc caccccggac accccggcua caucaacuuc uccuacgaag      180

uccucacccc acuaaaaugg uaccaaaaca ugauccgcca ccccuacacc uccuacggau      240

acgaacccau gggaggcugg cuccaccacc aaaucauccc cgucgucuca caacaaacac      300

cccaauccca cgcacuccaa ccccaccacc acauccccau gguccccgcc caacaacccg      360

gaauccccca acaacccaug augccccucc ccggacaaca cuccaugacc cccacccaac      420

accaccaacc aaaccucccc cuccccgccc aacaacccuu ccaaccacaa cccguccaac      480

cccaacccca ccaaccacuc caaccccaau cccccaugca ccccauccaa ccacuccucc      540

cccaaccacc ccucccaccc auguucucaa ugcaaucccu ccuucccgac cucccccucg      600

aagccuggcc cgccaccgac aaaaccaaac gcgaagaagu agauuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  7084
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt9)

<400>  7084
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uacucuucgc cugccuacuc ggcgccgcau      120

ucucaaugcc ccuccccccc caccccggcc accccggcua cauaaacuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaaaca ugauuagaca cccaucccuc cuccccgacc      240

ucccccucga agcauggccc gcaaccgaca aaaccaaacg cgaagaaguc gacuaaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  7085
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt9)

<400>  7085
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcacaugga uccucuucgc cugccuacuc ggagccgcuu      120

uuuccaugcc ccucccuccc caccccggcc accccggcua cauaaacuuc uccuacgaag      180

accucuaccu cgaagccauc cgcaucgacc gcaccgccuu cguccucaca ccccuuaaau      240

gguaccaaaa caugauccgc caccccuaca ccuccuacgg cuacgaaccc augggcgguu      300

ggcuccacca ccaaaucauc cccguagucu cacaacaaac cccacaaucc cacgcccucc      360

aaccccacca ccacauacca augguccccg cccaacaacc aggcaucccc caacaaccca      420

ugaugccccu ccccggccaa cacuccauga ccccaaccca acaccaccaa cccaaccucc      480

cccuccccgc ccaacaaccc uuccaacccc aacccgucca accccaaccc caccaacccc      540

uccaacccca aucccccaug caccccaucc aaccucuccu cccccaaccc ccacucccac      600

caauguucuc aaugcaauca cuccuccccg acuuaccccu agaagccugg cccgccaccg      660

acaaaaccaa acgagaagaa guagacuaag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  7086
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt9)

<400>  7086
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc ucauaugaag      180

uccucacacc ccucaaaugg uaccaaaaca ugauccgcca ccccacaccc caaucccacg      240

cccuccaacc acaccaccac auccccaugg uccccgccca acaaccaggc aucccacaac      300

aacccaugau gccccuacca ggccaacacu ccaugacccc cacccaacac caccaaccca      360

accuaccccu ccccgcacaa caacccuucc aaccacaacc cguccaaccc caaccccacc      420

aaccccuaca accccaaucc cccaugcacc caauccaacc ccuccucccc caaccacccc      480

ucccacccau guucuccaug caaucacucc uccccgaccu cccccuagaa gccuggcccg      540

caaccgacaa aaccaaacgc gaagaagucg acuaaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  7087
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt9)

<400>  7087
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccucccac cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguacucacc ccucucaaau gguaccaaaa caugauccga caccccuaca      180

ccuccuacgg cuacgaaccc augggcggcu ggcuccacca ccaaaucauc cccgucgucu      240

cccaacaaac accccaaucc cacgcacuac aaccccacca ccacaucccc augguccccg      300

cccaacaacc cggcaucccc caacaaccca ugaugccacu ccccggccaa cacuccauga      360

cccccaccca acaccaccaa cccaaccucc cccuacccgc ccaacaaccc uuccaacccc      420

aacccgucca accacaaccu caccaaccac uccaacccca aucacccaug caccccaucc      480

aaccacuccu accccaaccc ccacucccac ccauguucuc caugcaauca cuccuccccg      540

accucccccu agaagccugg cccgccaccg acaaaaccaa acgcgaagaa gucgacuaag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  7088
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt9)

<400>  7088
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaggagucg cccggcuacc ccuacuccua ggacuccucc      120

uacuaccacg cccuggacga ccccuagacc uggccgacua cacguacgac cuagccgaag      180

aagacgacuc cgaaccccuc aacuacaaag accccugcaa ggccgccgcc uuccuaggcg      240

acauagcccu agacgaagaa gaccuccgag ccuuccaagu ccaacaagcg gucgaccugc      300

gccgacacac ggccaggaaa ucauccauaa aagccgcugu accgggaaac acaucaaccc      360

ccucaugcca aucgacaaac ggacaaccac aaaggggcgc augcggaaga uggcgcgggc      420

gaucacgcuc acgccgcgca gccacaagcc gcccggagcg aguguggccc gacgggguaa      480

uacccuucgu cauaggggga aacuucacug gaucacaacg ggcagucuuu agacaagcaa      540

ugagacacug ggaaaagcau accugcguca cauuccuaga acggaccgac gaagauucau      600

acaucguauu caccuaccgc ccaugcggau guugcucaua cguaggccga agaggcggcg      660

gcccccaagc gauaucgaua ggcaagaacu gcgacaaauu cgggauaguu guacacgaac      720

uaggacacgu cguaggcuuc uggcacgaac acaccagacc cgaccgggac cggcacguau      780

ccauaguccg cgaaaacauc caacccggac aagaauacaa cuuccuaaaa auggaaccac      840

aagaagucga aucgcuaggc gaaaccuaug acuucgauuc caucaugcac uaugcucgca      900

acaccuucuc acgaggcauc uuccucgaca ccaucguccc caaauacgaa guuaacggag      960

ucaaaccacc cauaggacaa cgcacgcgac ucucaaaagg cgauaucgcu caagcacgca     1020

aacucuacaa gugucccgcc ugcggcgaaa cgcuccagga cucgacaggc aacuucucau     1080

cccccgaaua cccgaacgga uacagcgcac acaugcacug ugucuggcga aucucaguaa     1140

caccaggcga gaaaaucauc cuuaacuuca caucccucga ccuguacaga ucccgccucu     1200

gcugguacga uuacgucgaa gucagagacg gguucuggcg aaaagcaccg cuccgaggcc     1260

gauucugugg auccaaacug ccagaaccca uagucuccac agacucucga cucuggguug     1320

aguucagaag cucuaguaac ugggucggca aaggcuucuu cgccgucuac gaagcaaucu     1380

gcggaggaga cguaaagaaa gauuacggcc acauacaguc ccccaacuac cccgacgacu     1440

accggcccag uaaaguaugu aucuggagaa uccagguaag cgaaggcuuc cauguugggc     1500

ucaccuuuca gagcuucgaa auagaacgcc acgacucaug cgcuuaugac uaucucgaag     1560

uacgcgacgg ccacuccgaa ucaagcacac ucauaggcag auacugcgga uacgaaaaac     1620

ccgaugacau caaauccacg uccagccgcc uauggcucaa auucgucuca gauggaagca     1680

uaaacaaagc cggauuugcu guuaacuucu ucaaggaagu agacgagugc ucccgaccca     1740

accgcggcgg gugcgaacaa cgcugccuca acacacucgg uuccuacaaa ugcagcugcg     1800

acccaggcua cgaacuagcc ccugauaagc gucgcugcga agcagccugc gguggguucc     1860

ucacaaaacu aaacggaucc auaacaagcc cuggcuggcc aaaagaauau cccccuaaca     1920

agaacugcau cuggcaacug guggcgccca cacaauaccg aauaagccua caauuugacu     1980

ucuucgagac agaaggaaau gacgugugca aguacgacuu cguagaaguc cgcuccgggu     2040

uaaccgccga cuccaagcug caugggaaau ucugcggauc cgaaaaacca gaagugauua     2100

cgagccaaua caacaacaug cgagucgagu ucaagucaga caacacaguc uccaagaaag     2160

gcuuuaaagc ucacuucuuc ucagacaaag acgagugcuc aaaagacaau ggaggguguc     2220

aacaagacug cguuaacaca uucggguccu acgaaugcca augccgcucu ggguucguac     2280

uucacgauaa caagcacgac ugcaaagaag ccggaugcga ccacaaggug acaagcaccu     2340

ccggcaccau aacguccccc aacuggccag auaaauaccc cucaaagaaa gaaugcacgu     2400

gggccaucag uagcacuccc ggccacagag ucaaacucac auucauggaa auggacaucg     2460

aaagccagcc ggagugcgcg uacgaccacc ucgaaguguu cgacggacgc gacgcgaagg     2520

cuccagugcu cggccgauuc ugcggaucca agaagccaga accagucuua gcaacuggaa     2580

gccgaauguu ccuacgauuc uacuccgaca auuccguuca acgaaaaggc uuccaagccu     2640

cccacgccac cgaaugcggc ggacaagucc gagcggacgu aaaaaccaaa gaccucuaca     2700

gccacgcgca auucggggac aacaacuacc cagguggcgu agacugcgaa uggguaauag     2760

ucgcagaaga aggcuacgga gucgagcuag uauuccagac cuucgaaguu gaagaagaaa     2820

cagacugcgg cuacgacuac auggaacuau ucgacgguua cgacuccacc gcaccccggc     2880

ucggacggua cugcggcucc ggcccaccag aagaaguaua cucagcagga gacagcgucc     2940

ucgucaaauu ccacuccgau gauaccauaa caaagaaagg guuucaccua cgcuacacga     3000

gcaccaaauu ccaagacacu cuacacagcc gcaaauaagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  7089
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt9)

<400>  7089
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guagccggca cccgaugccu acucgcccuc cuucuccccc      120

aaguccuccu aggcggcgcc gccggccugg ucccagaacu aggccgccgc aaauucgcag      180

ccgcauccuc cggacgccca ucaucacagc ccuccgacga aguccucucc gaguucgaac      240

ucagacuacu aucgauguuc ggccuuaaac aacgccccac cccaucccgu gacgccguag      300

ucccaccaua caugcucgac cuauaccgcc gccacuccgg gcaacccgga ucaccagcac      360

ccgaccaccg ccucgaacgc gccgcauccc gcgccaacac aguccgcucc uuccaccacg      420

aagaaucccu cgaagaacuc cccgaaacau caggcaaaac aacccgccga uucuucuuca      480

accucuccuc cauacccaca gaagaguuca ucaccuccgc agaauuacaa gucuuccgcg      540

aacaaaugca agacgcacuc ggcaacaacu ccuccuucca ccacagaauc aacaucuacg      600

aaaucaucaa acccgcaacc gccaacagca aauucccagu aacccgacuc cuugacacac      660

gacucgucaa ccaaaacgcc uccagauggg aaucauucga cgucacacca gcagucaugc      720

gcuggaccgc ccaaggccac gcaaaccaug gauucguggu agaagucgcc caccuagaag      780

aaaaacaagg agucuccaaa cgccacgucc gcaucucacg cucccuccac caagacgaac      840

acucaugguc acaaauccga ccccuccuag uaacauucgg acacgacggc aaaggccacc      900

cccuacauaa acgcgaaaaa cgacaagcca aacauaagca acgaaaacgc cucaaaucaa      960

gcuguaaacg ucauccacuc uacgucgacu ucucugacgu cggcuggaac gacuggaucg     1020

uagcaccacc cggcuaccac gccuuuuacu gccacggaga augccccuuc ccccucgccg     1080

accaccuaaa uuccaccaac cacgcaauag uccaaacccu aguuaacucc gucaacucca     1140

aaaucccaaa agcaugcugc guucccacag aacucucagc aaucuccaug cucuaccuug     1200

acgaaaacga aaaagucguc cugaaaaacu accaagacau ggucgucgaa ggcugcggcu     1260

gccgauaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  7090
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt9)

<400>  7090
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auacccggca accguaugcu cauggucguc cuccucugcc      120

aaguacuccu cggcggagcc ucacacgcau cucucauacc cgaaacuggc aaaaaaaaag      180

ucgccgaaau ccaaggccac gcaggaggac gccgcucagg ucaaucccac gaacuccuac      240

gcgacuucga agccacccua cuacaaaugu ucggccuccg acgccgaccc cagcccucca      300

aauccgccgu cauacccgac uacaugcgcg accucuaccg acuucaaucc ggcgaagaag      360

aagaagaaca aauacacagc accggccucg aauaccccga acguccagcc ucccgcgcca      420

acaccguccg cucuuuccac cacgaagaac accucgaaaa cauccccggc acauccgaaa      480

acuccgccuu ccgauuccuc uucaaccuau ccucaauccc cgaaaacgaa gucauauccu      540

ccgccgaacu ccgucucuuc cgcgaacaag uagaccaagg ccccgauugg gaacgcggcu      600

uccaccgcau caauaucuac gaagucauga aaccaccagc cgaagucgua cccggacacc      660

ucaucacacg cuuacuagac acccgccucg uccaccacaa cguaacacgc ugggaaaccu      720

ucgacgucuc cccagcuguu cuccgaugga cacgcgaaaa acaacccaac uacggccucg      780

ccaucgaagu cacccaccuc caccaaaccc gaacccacca aggccaacac gucagaaucu      840

cccgcucucu cccccaaggc ucaggcaacu gggcccaacu acgcccccua cuugucaccu      900

ucggccacga cggacgaggc cacgcacuaa cgcgacgccg ccgcgccaaa cgcucaccca      960

aacaccacuc ucagcgcgcc agaaaaaaaa acaaaaauug ccgccgacac ucacuguacg     1020

ucgacuucag cgacgucggc uggaaugacu ggaucgucgc cccccccggc uaccaagcau     1080

ucuacugcca cggcgacugc ccauucccac uagcugacca ccucaacucg accaaccacg     1140

caauuguaca aacccucguc aauuccguca acagcuccau cccaaaagca ugcugcgugc     1200

ccaccgaacu cuccgcuauc uccaugcucu accucgacga auacgacaaa gucguacuca     1260

aaaacuacca agaaaugguc gucgaaggau gcggcugccg cuaaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  7091
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt9)

<400>  7091
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggucuag gccgccgcgc acaguggcuc ugcugguggu      120

ggggacuacu cugcuccugc ugcggcccuc cccccuuacg uccacccuua ccagcagccg      180

ccgccgcggc agcaggaggc caacuacucg gcgacggugg cucccccgga cgaacggaac      240

aacccccccc cucaccccaa uccucaagcg gcuuccucua ccgccgccuc aaaacccaag      300

aaaaacgaga aaugcaaaaa gaaauacuau ccguccuagg ccuuccacac cggccccgcc      360

cacuccacgg ccugcaacaa ccccagccac ccgcccuccg ccaacaagaa gaacaacaac      420

aacaacaaca acucccccgg ggugaacccc cuccaggccg ccuaaaaucu gccccucucu      480

ucaugcucga ccucuacaau gcccuauccg ccgauaacga cgaagaugga gcgucagaag      540

gagaacgcca acaaucaugg ccccacgaag ccgccuccuc aucccaacgc cgacaacccc      600

cgcccggcgc cgcccacccc cuaaaccgua aaucccugcu cgcccccggc ucaggcagcg      660

guggugcauc cccacucacc ucggcccaag acuccgcauu ccuaaacgac gcagacaugg      720

ucaugagcuu cgucaaccua gucgaauacg acaaagaauu cuccccacgc caacgacacc      780

auaaagaauu caaauucaac cucucacaga uacccgaagg agaagucguc accgccgcag      840

aauuccgaau cuacaaagac ugcguaaugg guagcuucaa aaaccaaaca uuccuaaucu      900

cuauauacca aguacuccaa gaacaccaac accgugacag ugaccuauuc cuccucgaca      960

cccgagucgu uugggccuca gaagaaggcu ggcucgaauu cgacaucaca gcaaccagca     1020

accuaugggu aguaacaccg caacacaaca ugggccuaca acuauccgua gucacccgag     1080

acggaguaca cguucacccg cgcgcagccg gccucguagg acgcgacggc cccuacgaca     1140

aacagcccuu cauggucgcc uucuucaaag ucuccgaagu acacguccgc accacccgcu     1200

ccgccuccuc ucgacgccgc caacaauccc gaaaccgauc cacccaaucc caagacgucg     1260

cccgcguuuc cucugccuca gacuacaauu ccucagaacu caaaaccgcc ugccgaaaac     1320

acgaacuaua uguaucauuc caagaccuug gcuggcaaga cuggaucauc gcccccaaag     1380

gcuacgcagc caacuacugc gacggcgaau gcuccuuccc acuaaacgcc cacaugaacg     1440

ccaccaacca cgccaucguc caaacacucg ugcaccuuau gaaccccgaa uacguaccca     1500

aaccaugcug cgcccccacc aaacuaaacg ccaucuccgu acucuacuuc gaugacaacu     1560

ccaacgucau acuaaaaaaa uaccguaaca ugguaguacg cgccugcggu ugccacugag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  7092
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt9)

<400>  7092
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacgugcguu cacuacgagc agccgcccca cacucauucg      120

ucgcccucug ggcuccccuu uuucuccuac gcucugcccu cgccgacuuc ucccuagaca      180

acgaaguaca cagcucauuc auccaccgcc gucuccgcuc ucaagaaaga cgcgaaaugc      240

aacgugaaau ccucuccauc cucggccucc cccaccgacc ccgcccccac cuacaaggca      300

aacacaacuc cgcccccaug uucaugcucg accucuacaa cgccauggcc guagaagaag      360

gaggaggacc cgguggccaa ggcuucuccu accccuacaa agccgucuuu uccacccaag      420

gucccccgcu cgcaucacuc caagacuccc acuuccucac cgacgccgac auggucaugu      480

cauucgucaa ccuugucgaa cacgacaaag aguucuucca cccccgcuac caccaucgcg      540

aguuccgcuu cgaccucagc aaaauucccg aaggcgaagc cgucaccgcc gccgaguucc      600

gaaucuacaa agacuacauc cgugaacgcu ucgacaacga aacuuuccgc aucucagucu      660

accaaguccu ccaagaacac cuaggccgcg aaucagaccu cuuucuccuc gacucacgaa      720

cccucugggc cucagaagaa ggauggcucg ucuucgacau cacagccaca uccaaccacu      780

gggucgucaa cccucgccac aaccuuggac uccaacuguc cgucgaaacc cucgacggcc      840

aauccauaaa ccccaaacuc gccggccuca uaggccgaca cggaccccaa aacaaacaac      900

cauucauggu cgcauuuuuc aaagcaaccg aaguccacuu uagauccauc cguuccaccg      960

gaucaaaaca acgcucccaa aaccgcucca aaacccccaa aaaccaagaa gcccuccgca     1020

uggccaacgu agcagaaaac uccuccagcg accaacgcca agccugcaaa aagcacgaac     1080

ucuacguauc auuucgagac cucggcuggc aagacuggau aaucgcccca gaaggcuacg     1140

ccgcauacua cugcgaagga gaaugcgccu ucccccuaaa uuccuacaug aacgccacca     1200

accacgccau cguccaaacc cucguccacu ucaucaaccc cgaaacuguc ccaaaacccu     1260

gcugcgcccc cacacaacua aacgccaucu caguccucua cuuugacgac ucaucuaacg     1320

uaauccuaaa gaaauaucgc aacaugguag uccgcgccug cgguugccac uagggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  7093
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt9)

<400>  7093
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagccuccg ccgcccuccu augccuccuc cucaccgccg      120

ccgcauucuc cccccaaggc cucgcccaac cagucggcau aaacaccucc accaccugcu      180

gcuaccgauu caucaacaaa aaaaucccaa aacaacgacu cgaauccuac cgccgcacca      240

ccuccuccca cugcccccga gaagccguca ucuucaaaac caaacucgac aaagaaaucu      300

gcgccgaccc aacccaaaaa uggguccaag acuucaugaa acaccuagac aaaaaaaccc      360

aaaccccaaa acucuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  7094
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt9)

<400>  7094
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cucuuaaccc uuaucauacu ucuucccguc gucagcaagu      120

ucagcuuugu cucacucagu gcaccccaac acuggagcug ccccgaagga acacuugccg      180

gcaacggcaa uagcacaugc guugggccgg cucccuuccu aauauucagc cacggaaaca      240

gcauauuccg aaucgacaca gagggaacca acuacgaaca gcugguaguc gacgcuggcg      300

uaagcgucau cauggacuuc cacuacaacg agaagcgaau cuacugggua gaucucgaac      360

gccaacuacu gcaacgggua uucuugaacg gcucgcgaca ggagcgcguc ugcaauaucg      420

aaaagaacgu cucaggaaug gcuaucaacu ggauuaauga agaggugaua uggagcaacc      480

aacaggaggg aaucauaacc gucacagaca ugaaggguaa caacucccac auccuucuca      540

gcgcgcucaa auacccugca aaugucgccg uggauccugu cgaacguuuu auauucuggu      600

caagugaagu agccggcucc cucuacagag ccgaccucga cgguguaggg gucaaggcac      660

uacucgaaac guccgagaaa auaacagcag uaucgcugga cguacucgac aaacgccuau      720

ucuggauuca guacaaccga gaaggcagca acuccuuaau cugcaguugc gacuacgacg      780

gagguagcgu gcauauaagu aaacacccaa cgcagcacaa ccuauuugcc augucacugu      840

ucggggaccg caucuucuac agcaccugga aaaugaaaac aauauggauc gcaaacaaac      900

acaccggcaa ggauaugguc cgcaucaacc uacacucuuc auucguaccc cuaggggagc      960

ucaaaguagu gcacccucuc gcccaaccaa aagcagagga ugauaccugg gaacccgaac     1020

aaaagcugug caaacuccga aagggcaacu gcucgagcac cgucugcgga caagaccugc     1080

aaagccaccu cugcaugugu gcggaaggau acgcacucuc acgagaccgg aaguacugcg     1140

aggacgucaa cgaaugcgcc uucuggaacc acggaugcac ucuuggaugu aagaacaccc     1200

caggauccua uuacuguacc ugcccagucg gauucguacu acuaccagac ggaaaacgau     1260

gccaccaacu gguauccugc ccccgaaacg uauccgaaug cucccacgau ugcguccuaa     1320

ccucagaggg gccccucugc uucugcccag agggauccgu guuagaacgc gacggcaaga     1380

cuugcagcgg cugcagcagc ccagacaacg gcgggugcag ccaacuaugc guaccacuau     1440

caccaguuuc augggaaugc gacugcuucc cggguuacga ccuccagcuc gacgaaaaau     1500

caugugcggc cagcggacca cagcccuucc uccuauucgc caauucacaa gacauccggc     1560

acaugcacuu cgacggcacc gacuacggua cccuacugag ccaacaaaug gguauggugu     1620

acgcgcucga ccacgaccca guagaaaaca aaauauacuu cgcccacaca gcccucaagu     1680

ggaucgaacg agccaacaug gauggaucac aacgcgagcg gcuaauagag gaaggugugg     1740

acgugccaga aggccuggcc guagacugga uaggccgcag auucuauugg acagacagag     1800

guaaaucacu caucggacga ucagaccuca acggcaaaag guccaaaauc aucacuaaag     1860

agaacauauc acaaccacgc ggcauagccg uccaccccau ggccaaacgc cucuucugga     1920

ccgacacggg caucaaccca agaauagagu ccagcagccu ccagggccua ggaagacuug     1980

uaaucgcauc guccgaucuc auuuggccca gcgggaucac aaucgauuuc cuaacugaca     2040

aacucuacug gugcgacgcc aaacaaagug uaaucgaaau ggcaaaccuc gacggaucga     2100

aacgacggcg ccucacccaa aacgauguug gccaucccuu cgcaguagca gucuuugagg     2160

acuacgucug guucagcgac ugggccaugc ccuccguaau gcggguuaac aaacgcaccg     2220

gcaaagaccg aguccgacua caggguucca ugcuuaaacc gagcucccua guuguaguac     2280

acccacuagc aaaacccggg gccgaccccu gcuuauauca aaacggagga ugcgaacaca     2340

ucugcaagaa acgccucggc accgcauggu guagcugccg agaaggauuu augaaagccu     2400

ccgacggcaa aaccugucug gcccuagaug gccaccaacu ccuugcgggc ggcgaaguag     2460

accuuaaaaa ccaagugacc ccgcuagaca uacucucaaa aacgcgcguc ucagaagaca     2520

acaucacaga aagccaacac augcucguag cagaaaucau gguaagcgac caagacgacu     2580

gcgcacccgu aggaugcagc auguaugcac ggugcauaag cgaaggagaa gacgcgaccu     2640

gccaaugccu aaaaggauuc gccggagacg guaagcucug cucagauauu gacgaaugcg     2700

aaaugggagu acccgugugu ccacccgcca gcucaaagug caucaacacu gaaggaggcu     2760

acgucugcag augcagcgag ggcuaucaag gcgacggcau ccauugccua gauauagacg     2820

agugccagcu aggcgagcac ucgugcggcg agaacgcguc gugcacaaac acggaaggug     2880

gcuauacaug caugugcgcc ggaagacuca gcgaaccggg ucuaauuugc cccgacagca     2940

ccccaccucc acaccuucgc gaagacgacc accacuacuc cguccgcaac ucggacucag     3000

aaugcccccu cagucaugau ggcuacugcu ugcaugacgg cguuuguaug uauaucgaag     3060

cccuagacaa guacgcaugc aacugcgucg uagguuacau cggagagcgc ugccaauauc     3120

gcgaccuaaa auggugggaa cucagacacg caggucacgg ucagcaacaa aagguuaucg     3180

ucguagccgu uugugucgug guccuaguca ugcuccuucu ccuaucgcuc uggggcgccc     3240

acuacuacag aacccaaaaa cuccuaucca aaaacccgaa aaaucccuac gaagaaucga     3300

guagggacgu acguucgcga cgacccgcag acacggaaga cggcaugagu ucgugccccc     3360

aaccaugguu cguaguuauu aaggaacauc aagauuugaa aaacggcgga cagccagucg     3420

ccggagagga cggccaagca gcagauggau ccaugcaacc cacaucaugg agacaagaac     3480

cccaacuaug cggaauggga acggaacaag gcugcuggau uccagucagu uccgacaaag     3540

gcucaugccc acaaguaaug gaacgaucgu uccacaugcc auccuacgga acccaaacac     3600

ucgaaggcgg uguagaaaag ccacacagcc uccucucggc aaacccccua uggcagcagc     3660

gcgcacuaga cccuccccau caaauggagc ugacccaaua gggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  7095
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt9)

<400>  7095
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggca gacgcaugga aaugcuaugc gccggccgag      120

uccccgcacu ccuacucugc cucggcuucc accuccuaca agccguccua uccaccacag      180

ucaucccauc augcauccca ggcgaaagcu cugacaacug caccgcccua guccaaaccg      240

aagacaaccc ccgcgucgcc caagucucca ucacaaaaug cucauccgac augaacggcu      300

acugccuaca cggccaaugc aucuaccucg ucgacauguc ccaaaacuac ugcagaugcg      360

aagucggcua caccggaguc cgcugcgaac acuucuuccu cacaguacac caaccucucu      420

ccaaagaaua cgucgcccuc accgucauac ucauuauccu cuuccucauc accguagucg      480

gcuccacaua cuacuucugc cgcugguacc gcaaccgcaa auccaaagaa cccaaaaaag      540

aauacgaacg cgucaccucc ggcgaccccg aacuccccca aguauaagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  7096
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt9)

<400>  7096
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgaaggcg aaaucacaac cuucaccgcc cucaccgaaa      120

aauucaaccu cccccccggc aacuacaaaa aacccaaacu ccuauacugc uccaacggcg      180

gacacuuccu ccguauacuc cccgacggca cagucgacgg cacccgagac cgcucugacc      240

aacacaucca acuccaacuc ucagccgaau cagucggcga agucuacaua aaauccaccg      300

aaacaggcca auaucucgca auggacaccg acggccuucu cuacggcucc caaaccccca      360

acgaagaaug ccucuuccuc gaacgccuag aagaaaacca cuacaacaca uacaucucca      420

aaaaacacgc agaaaaaaac ugguucguag gccucaaaaa aaacggcucc ugcaaacgcg      480

gcccccgcac ccacuacggc caaaaagcca uccucuuccu cccccuaccc gucucauccg      540

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  7097
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt9)

<400>  7097
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guagggguag gaggagggga uguagaagau gugacgccaa      120

ggccaggagg gugucaaaua agcggaagag gggcaagagg cuguaacggg auaccggggg      180

cagcggcgug ggaggcagcg cugccgagaa gacgaccacg aaggcauccg agugugaacc      240

cgcggucaag agcggcaggg agcccgagaa cgagagggag aagaacagag gaaaggccaa      300

guggaaguag auuaggggau aggggaagag ggagggcgcu accgggaggg agauugggag      360

ggcgagggag agggagagcg ccagagaggg uaggagggcg ggggcggggg agggggacag      420

cggcgccgag agcggcacca gcagcgagag ggagcaggcc agggccggcg gggacgaugg      480

cggcgggaag cauaacaaca cugccggcgu uaccggagga cggagggagu ggggcguucc      540

cgccagggca cuuuaaagau ccaaagaggu uguauugcaa aaacggaggg uucuuucuga      600

ggauacaucc agaugggaga guagauggag uaagggagaa aucggaccca cacauaaaac      660

ugcaauugca agcagaagag agagggguag ugagcauaaa aggggugugu gcaaacagau      720

accuagcgau gaaggaagau ggaagacugu uagcgucgaa auguguaacg gacgagugcu      780

uuuucuuuga aaggcucgag agcaauaacu auaacacaua caggagcagg aaguauacau      840

caugguaugu agcacucaag agaacgggac aauacaagcu agggagcaag acggggccgg      900

ggcaaaaggc aauacuauuu cuaccgaugu cggcaaagag cuagggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  7098
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt9)

<400>  7098
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uccucaccug gauccuaccc acccuccugu      120

accgcagcug cuuccacauc aucugccucg ucggaaccau aucccucgcc ugcaacgaca      180

ugacccccga acaaauggcc acaaacguaa acugcagcuc ccccgaacgc cacacccgcu      240

ccuacgacua cauggaaggc ggagacaucc gcguacgccg ccuauucugc agaacccaau      300

gguaccuacg cauagacaaa agaggcaaag ucaaaggcac acaagaaaug aaaaacaacu      360

acaacaucau ggaaauccgc accgucgcag ucggaaucgu agccaucaaa ggagucgaaa      420

gcgaauucua ccuagccaug aacaaagaag gcaaacuaua cgccaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa cuaauccucg aaaaccacua caacaccuac gccuccgcca      540

aauggaccca caacggcggc gaaauguucg uagcccucaa ccaaaaagga auacccgucc      600

gcggaaaaaa aaccaaaaaa gaacaaaaaa ccgcccacuu ccuccccaug gccaucaccu      660

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  7099
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt9)

<400>  7099
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuccucc ccuccgucgu ccucaaacuc uuccuagccg      120

caguccucuc cgcacucguc accggcgaau cccucgaacg acuccgacgc ggccuggccg      180

caggcaccuc caaccccgac ccaccaaccg ucucaacaga ccaacuacua ccccucggcg      240

gaggccgcga cagaaaaguc cgcgaccuuc aagaagcaga ccucgaccuc cuccgaguca      300

cccucuccag caaaccccaa gcccucgcca cacccaacaa agaagaacac ggaaaacgca      360

agaaaaaagg caaaggccuc ggcaaaaaac gcgaccccug ccuacgcaaa uacaaagacu      420

ucugcaucca cggggaaugc aaauacguca aagaacuacg cgcccccuca ugcauaugcc      480

accccggcua ccacggcgaa cgcugccacg gccucucccu ccccguagaa aaccgacucu      540

acaccuacga ccacaccacc auccucgccg ucgucgccgu cguccucucc uccguaugcc      600

uacucgucau cguaggccuc cuaauguucc gcuaccaccg ccgaggcggc uacgacgucg      660

aaaacgaaga aaaagucaaa cucggaauga ccaacuccca cuaaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  7100
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt9)

<400>  7100
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggucacga aacuccuccc agcacuacua cuacaacacg      120

uccuauuaca ccuccuccuc cuacccauag caauacccua cgcggaaggg cagcgaaaaa      180

gacgcaacac gauccacgag uucaagaagu ccgcaaaaac aacccuaauc aaaauagacc      240

ccgcccucaa aaucaaaacc aagaaaguca auaccgcaga ccaaugcgca aaccgcugca      300

cacgcaacaa aggccuccca uuuaccugca aagccuucgu uuuugacaaa gccagaaagc      360

aaugccuuug guucccauuc aacagcauga gcuccggcgu caagaaagag uucggacacg      420

aguucgaccu guacgaaaac aaagacuaca uccgaaacug cauaaucggc aaaggccgca      480

gcuacaaagg aacagucucc auaaccaaau caggcaucaa augccagccu uggagcucca      540

ugauacccca cgaacacuca uuccucccgu caagcuaccg agggaaagac cuacaagaaa      600

auuacugccg aaacccacgc ggggaagaag gcggacccug gugcuucacc ucaaacccag      660

aaguccgcua cgaaguaugc gacauccccc aaugcucaga aguugaaugc augaccugca      720

auggagaaag cuacagaggg cucauggacc acaccgaaag cggcaaaaua ugccaacgau      780

gggaccacca aacaccacac cgacacaaau uccuccccga acgauacccg gacaaagggu      840

ucgaugacaa cuacugccgu aaccccgacg gccagccacg cccauggugc uacacacuag      900

acccacacac ucgcugggaa uacugugcaa ucaaaacaug cgccgacaau accaugaacg      960

acacagacgu cccccuggaa acaaccgaau gcauccaagg ccaaggugaa ggcuaccgcg     1020

gcacggucaa uaccauaugg aacggcauac ccugccaacg augggacagc caauacccgc     1080

acgaacacga caugacacca gaaaacuuca aaugcaaaga ccuucgggaa aacuacugcc     1140

gaaaccccga cggauccgaa agccccuggu gcuucacaac cgaccccaac auccgcguag     1200

gauacuguuc acaaauccca aacugugaca ugagccacgg acaggacugc uacagaggua     1260

acggcaaaaa cuacaugggc aaccucuccc aaacacgauc cggacugacc ugcagcaugu     1320

gggacaagaa cauggaagau cuccauagac acaucuucug ggaaccagac gcaagcaaau     1380

uaaacgaaaa cuacugccga aaccccgacg acgacgccca cggccccugg ugcuacacag     1440

gaaacccucu gauucccugg gauuauuguc ccaucucccg cugcgagggc gacaccaccc     1500

ccacaaucgu gaaccuagac caccccguaa uaucaugcgc aaaaacgaaa cagcuccgag     1560

uugugaacgg cauaccaacu agaacuaaca ucggcuggau ggucucacua cgauaccgua     1620

acaaacacau cugcggaggu ucgcuaauaa aagaaagcug gguccucacc gcacgccaau     1680

gcuuccccag ccgggaucug aaagacuacg aagccuggcu gggaauacac gacguccacg     1740

guagaggaga cgaaaaaugc aaacaggucc ucaacguauc ccaacucgua uacggcccgg     1800

agggcaguga ccucguacuc augaaacuag cccgacccgc cguccuugac gacuucguau     1860

ccaccauaga ccuccccaac uacggcugca ccaucccaga aaagaccagc ugcagcgucu     1920

acggaugggg auacaccggc cuaauaaauu acgacgggcu acuccgcguc gcccaccugu     1980

acaucauggg caacgaaaaa ugcucccagc accacagagg caaaguaacc cuaaaugaaa     2040

gcgaaauaug cgcaggggcc gagaaaaucg gcaguggccc augcgaaggc gacuacgggg     2100

gcccccuagu augcgaacaa cauaaaaugc gcaugguccu cggagugauc guccccggac     2160

gaggcugcgc gaucccaaau cgcccaggca ucuucguccg cguggcuuac uacgccaaau     2220

ggauacacaa aauaauacua accuacaaag uaccccaaag cugaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  7101
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt9)

<400>  7101
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuaaagcgg cggcaaucgg aauagaccuc ggaaccaccu      120

acucaugcgu gggcguuuuu cagcacggca aaguagaaau aauagcaaac gaucaaggaa      180

acaggacaac ucccucguac guggcauuua cagacacaga gagacugauu ggggacgccg      240

ccaaaaacca agucgcacug aacccccaga acacaguuuu cgacgcgaaa aggcucauag      300

gacgaaaauu cggagaccca gugguccaaa gugacaugaa gcacuggcca uuccaaguga      360

uaaaugacgg cgacaaaccc aagguacaag ucucguacaa aggcgaaacc aaggcauucu      420

acccagaaga gauaucgucc augguccuca caaagaugaa agaaauagcc gaagccuacc      480

ucggguaccc agucacaaac gcggucauaa ccguacccgc guacuucaac gacagccaac      540

gacaagcgac aaaagacgcc ggagucauag caggccucaa cguacugcgc auaaucaacg      600

aaccgaccgc ggcagccaua gccuacgggc uagaccgcac aggaaaaggg gagcgcaacg      660

ucuuaaucuu cgaccuaggc ggaggcacau ucgacgucuc aauacuaacc auagacgacg      720

gcaucuucga aguaaaagcc acagccgggg acacgcaccu aggcggcgaa gacuucgaua      780

accgccuagu aaaccacuuc guagaagagu ucaagagaaa gcacaagaaa gacauaagcc      840

aaaacaaacg ggccgugcgc aggcuaagga ccgcaugcga acgcgcaaaa cgaacccuca      900

gcucaaguac ccaagcaagc cuggaaaucg acagucucuu cgaaggaaua gacuucuaca      960

ccuccaucac ccgagcgcga uucgaagaac uaugcagcga ccuauuccgc ucgacacugg     1020

aaccggugga aaaagcacuc agagacgcga agcuagacaa agcccaaauc cacgaccuag     1080

uauugguggg aggcaguaca agaaucccaa aaguacaaaa gcuccuacaa gauuucuuca     1140

acggaaggga ccucaacaaa uccaucaacc ccgacgaagc aguggccuac ggggcagcag     1200

uccaggcagc cauacugaug ggagacaaaa gcgaaaacgu gcaagaccua cuccuccugg     1260

acguagcccc acuaagccua ggacucgaaa cagccggagg aguaaugaca gcacugauaa     1320

aaaggaacag caccaucccc acgaaacaaa cccaaaucuu cacaacguac ucagacaacc     1380

aacccggagu gcuaauacaa guauacgaag gcgagcgcgc aaugacuaaa gacaacaacc     1440

uccugggcag guucgagcua ucaggaauac caccggcacc acggggaguc ccgcaaauag     1500

aagugaccuu cgacauagac gccaauggca uacuaaacgu aaccgcaacc gacaaaucua     1560

ccgggaaagc aaacaagaua acgaucacga acgauaaagg gcgcuuaagc aaggaagaaa     1620

ucgaacgcau gguccaagaa gcagaaaaau acaaagccga ggacgaagua caacgcgaaa     1680

gagugagcgc gaaaaacgca cuagaaucau acgcguucaa caugaaaagc gcagucgaag     1740

acgaaggccu caaagggaaa auauccgagg ccgauaaaaa gaaaguacua gacaaaugcc     1800

aagaagucau aagcuggcua gacgccaaca ccuuagccga aaaagacgag uucgaacaca     1860

aaaggaaaga acuggaacaa guaugcaacc ccauuauauc cggccuauac caaggagcug     1920

gaggaccggg acccggcgga uucggagccc aaggccccaa aggaggaagu gggagcgggc     1980

ccacgauaga agaagucgac uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7102
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt9)

<400>  7102
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgaaagccg cagccaucgg aauagaccuc ggcaccaccu      120

acucaugcgu cggcguauuc caacacggga aaguagagau caucgcaaac gaccaaggaa      180

acaggaccac accaucauac guagccuuca cagacaccga gcgccuaauc ggagacgccg      240

ccaagaacca aguugcgcuc aacccacaaa acacagucuu cgacgcaaaa cgacugauag      300

gccgaaaauu cggcgaccca gugguccaau ccgacaugaa gcacuggcca uuccaaguaa      360

ucaaugacgg agacaaaccc aaaguacagg ucagcuacaa aggagaaaca aaggccuucu      420

acccagaaga aauaagcuca augguccuga ccaaaaugaa agaaauagca gaggcuuacc      480

ucggcuaccc cguaacaaac gcggucauca ccguacccgc auacuucaac gacagccaac      540

ggcaagccac gaaagacgcc ggagucauag caggccuaaa cguacuccgc auuauaaacg      600

aaccaaccgc cgccgccauc gcauacggac ucgaccgaac aggcaagggc gagagaaacg      660

uacugaucuu cgaccucgga ggaggaacau ucgacgucag uauacucacg aucgacgacg      720

gaauauucga gguaaaggca acggcuggag acacacaccu aggcggagaa gacuucgaca      780

acaggcuugu caaccacuuc gucgaagagu ucaaacgaaa acacaagaaa gacauaagcc      840

aaaacaaaag ggccguccgu agacuaagaa ccgccugcga aagagcgaaa aggacacuca      900

gcuccucaac ccaagcaagc cuagaaauag acucacuauu cgaaggcauc gacuucuaca      960

ccucgaucac ccgugcacgu uucgaagaac uaugcagcga ccucuuccgc ucaacccuag     1020

aacccguaga aaaagcacua cgagacgcga aacuagacaa agcgcaaaua cacgaccugg     1080

uccuaguagg aggcucaaca agaauaccua aaguacaaaa acucuugcaa gauuucuuca     1140

auggccgcga ccucaacaaa agcauaaacc cagacgaagc cgucgcauau ggagccgcgg     1200

ugcaggcagc aauccuaaug ggagacaaaa gcgaaaacgu gcaagaccug cugcuccuag     1260

acguagcacc acucucacuu ggccucgaaa ccgcaggagg cguaaugacu gcacuuauca     1320

aaaggaacuc gaccauaccc accaaacaga cacaaaucuu cacuacauac ucggacaacc     1380

agcccggagu ccuuauccaa guauacgagg gcgaacgcgc gaugacaaaa gacaacaacc     1440

uacucggaag auucgaacuc ucaggaauac caccagcccc acgcggcguc ccacaaaucg     1500

aaguaacauu cgacaucgac gcgaacggaa uauuaaacgu cacagccaca gacaaaucga     1560

ccggaaaagc aaacaaaaua acaaucacaa acgacaaagg ccgacuuagu aaagaagaaa     1620

ucgagcgaau ggugcaagaa gcggagaaau acaaagcaga agacgaagua caaagagagc     1680

gaguauccgc caagaacgcc cucgaaucau acgccuucaa caugaaaagc gcggucgaag     1740

acgaaggccu aaaggggaag auaagcgaag cagacaagaa gaaaguacua gacaaaugcc     1800

aagagguaau cagcuggcua gacgcaaaca cccucgcuga aaaagacgag uucgaacaca     1860

aacgaaaaga acucgagcaa gucugcaacc ccauaaucuc gggccucuau cagggagcgg     1920

gaggacccgg cccagggggc uucggagcgc aaggacccaa aggcggcagc ggaagcggcc     1980

ccacaaucga agaaguagac uagggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7103
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt9)

<400>  7103
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccacagcca aggggaucgc aaucggcauc gaccuaggaa      120

ccacauauuc cugcguagga gucuuccagc acggcaaagu ggaaauaauc gcaaacgauc      180

aaggcaacag aacaacccca agcuacguag cauucaccga cacagagaga cugaucggcg      240

acgccgcgaa aaaccaagug gcaaugaacc cacagaacac cgucuucgac gccaaacggc      300

ucauaggcag aaaauucaac gaccccguag uacaagccga caugaaacuc uggcccuuuc      360

aagucauaaa cgaaggcgga aagcccaaag uccuaguaag cuacaaaggc gaaaacaagg      420

ccuucuaccc cgaagaaauc ucgagcaugg uccucaccaa gcugaaggaa acagcagaag      480

ccuuccuagg ccacccagua acaaacgccg uaauaacagu gccagcauac uucaacgaca      540

gccaacgaca agcgaccaag gaugcgggug uaauagcggg ccucaacguc cuacgaauca      600

uaaacgaacc uacagcggcc gccaucgccu acggacugga caaaggaggc cagggagaaa      660

gacacguacu gauauucgac cuaggaggcg gcaccuucga cgucucaaua cugaccaucg      720

acgauggcau cuucgaagua aaagccacug caggcgacac ccaccucggc ggcgaagacu      780

ucgacaaccg gcucgucagc cauuucgucg aagaauuuaa aaggaaacac aagaaagaca      840

ucucccagaa caaaagagca gucagacgac uucggaccgc gugcgaacgc gcaaaacgca      900

cgcuaagcag caguacacaa gcaaaccuag aaaucgacuc ccuuuacgaa ggaaucgacu      960

ucuacacauc aaucacccgc gcaagguucg aggagcucug cgccgaccuc uuccguggca     1020

cccuagaacc cgucgaaaaa gcacuccgcg acgccaaaau ggacaaggca aaaauacacg     1080

acaucguacu cgucgggggc ucaaccagaa uccccaaggu ccagcgccua cuacaagauu     1140

acuucaacgg acgagaccuc aacaaaagca uaaauccaga cgaagcgguc gcguacggcg     1200

cagcaguaca ggccgcgauc cuaauggggg acaaaagcga aaaaguccaa gaccuccucc     1260

ugcuagacgu agcaccgcuu ucccuaggcc uagaaacagc cggaggugua augaccgccc     1320

uaaucaaacg caacagcaca auacccacca aacaaaccca aaucuucacc acauacagcg     1380

acaaccagcc gggcguccuc auacagguuu acgaaggcga acgcgcaaug acaaaagaca     1440

acaacuuacu aggacgauuc gaccugaccg gcaucccacc agcacccaga ggcguccccc     1500

aaauagaagu aaccuuugac auagacgcca acggcauacu aaacguaaca gccacagaca     1560

aaaguacggg caaagucaac aaaaucacca uaaccaacga caaaggcagg cucucaaaag     1620

aagaaaucga acggaugguc cuagacgcag aaaaauacaa agcagaagac gaaguacagc     1680

gagagaaaau agcggccaaa aacgcacucg aaagcuacgc cuucaacaug aaaagcguug     1740

uauccgacga aggauuaaaa ggaaaaauaa gcgaaagcga caaaaacaaa auacucgaca     1800

aaugcaacga acuccugucc uggcuggaag uaaaccaacu cgccgaaaaa gacgaguucg     1860

accacaaacg aaaagaacuc gaacaaaugu gcaaccccau aaucaccaaa cuguaccaag     1920

gcgguugcac cggaccagcc ugcggaaccg gcuauguacc cggacgccca gcgacaggcc     1980

caaccaucga agaggucgac uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7104
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt9)

<400>  7104
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgcacgcg gccccgcaau cgggaucgau cuaggcacca      120

cauacucgug cguaggcgua uuccaacacg ggaaagucga aaucaucgca aacgaccaag      180

gaaaccgcac cacccccagc uacguagccu ucaccgacac cgaacgacuc aucggagacg      240

cagccaaaaa ccagguagca augaacccaa ccaacacaau cuucgacgca aaaaggcuga      300

uaggccgaaa auuugaggac gccacggucc aaagugacau gaaacauugg cccuuccgcg      360

uaguauccga aggaggcaaa cccaaagucc aaguagaaua caagggcgag accaagaccu      420

ucuucccgga agaaauaucc agcauggucc ugaccaaaau gaaagaaaua gccgaagccu      480

accuuggggg aaaaguccac agcgccguca uaaccguucc agccuacuuc aacgacagcc      540

aacggcaagc cacgaaagac gcaggcacaa uaacaggacu caacguccuu cgaauaauaa      600

acgaaccaac cgcagccgcg aucgcauacg ggcucgacaa aaaggggugu gcagggggcg      660

agaaaaacgu guuaauauuu gaccuaggcg ggggcaccuu cgacguaagc auccucacca      720

uagaagacgg cauauuugaa gucaaaagca ccgccggaga cacacaccug ggaggagaag      780

acuucgacaa ucggauggua agccaccucg cagaagaguu caagcgcaag cacaagaaag      840

acauugggcc aaacaaaagg gccgugcgac gccucagaac cgcaugcgaa cgcgcaaaac      900

gcacccugag cucaaguacg caagcaagca ucgaaauuga cagucuguac gaaggaguag      960

acuucuacac aucaauaaca cgagcacgcu ucgaagaacu caacgccgac cucuuccgcg     1020

gaacacuaga acccgucgaa aaagcacucc gggacgcaaa acuggacaaa ggccaaaucc     1080

aagaaauagu acucgucggg ggauccaccc gaauaccaaa gauacagaaa cuacugcaag     1140

acuucuucaa cgggaaagaa cuaaacaagu cgauaaaccc cgacgaagca guagcguacg     1200

gcgccgccgu acaagccgcg auccugauag gagauaaaag ugaaaacgug caagaccuac     1260

ugcuccugga cgucacgccc cuaucacucg ggaucgaaac cgcuggcgga guaaugacac     1320

cccucauaaa aaggaacacc accauaccaa ccaaacaaac ccaaacauuc accaccuacu     1380

cggacaacca aucaucugug cuaguacaag uauacgaagg cgaacgggcu augacgaaag     1440

acaacaaucu acuagguaag uucgaccuaa caggcauacc cccggcaccc cgaggaguac     1500

cacaaauaga aguaaccuuc gacaucgaug caaacgggau acuaaacgua accgcagccg     1560

acaaaucgac cggaaaagaa aacaaaauca caaucacaaa cgacaaagga cgccucagca     1620

aagacgacau agaccgaaug guucaggaag cagagaggua caagagcgaa gacgaagcga     1680

accgagaccg aguggcggcc aaaaacgcac uggaaagcua caccuacaau auaaaacaaa     1740

caguugaaga cgaaaaacuc cguggaaaga ucagcgaaca agacaaaaac aaaauacuag     1800

acaaaugcca agaagucaua aacuggcugg accgaaacca gauggccgaa aaagaugaau     1860

acgaacacaa acaaaaagag cuagagcgcg uaugcaaccc cauaaucucg aaacuguacc     1920

aaggcggacc aggaggagga agcggaggag gaggaucggg cgcaagcggc ggcccgacaa     1980

ucgaagaggu cgacugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7105
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt9)

<400>  7105
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguaguag gcaucgaccu aggguuucag agcugcuacg      120

ucgcagucgc aagagcgggu ggcauagaaa caauagcaaa cgaauacagc gacagaugca      180

cccccgcaug caucucguuu ggccccaaaa auagaagcau uggagcugca gccaaaagcc      240

aagucaucag caacgcgaaa aacacgguac aaggcuucaa gcgguuucac ggaagggcau      300

ucagcgaccc cuucguugaa gcggagaagu ccaaccuagc guacgacauc guccaacuac      360

ccaccggacu gaccgguaua aaaguaacau acauggaaga agaaaggaac uuuacaacag      420

aacaaguaac cgccaugcuc cucagcaaac uaaaagaaac agcagaaucc guccucaaga      480

aacccgucgu cgacugcguc gugucggucc ccugcuucua caccgaugca gaaaggcgcu      540

cagucaugga cgcgacgcag auagcggggc ucaacugccu acgccuaaug aacgagacga      600

cagcagucgc ccucgccuac ggcaucuaca aacaagaccu ucccgcacua gaagaaaaac      660

cccgaaaugu cgucuucguc gacaugggac acucagcaua ccaaguaucu guaugcgcgu      720

ucaaccgagg caaacuuaaa gugcuggcca ccgccuucga cacaacacuc ggcggccgga      780

aauucgacga aguccuagua aaucacuucu gcgaagaguu cggcaagaaa uauaaacuag      840

auauaaaauc caaaauacgc gcccuccugc gcuugagcca ggaaugcgaa aaacucaaaa      900

agcuaaugag cgcaaacgcg ucagaccugc cacugagcau agaaugcuuc augaacgacg      960

uagacguauc cggaaccaug aaccggggaa aauucuuaga aaugugcaac gaccuccuag     1020

cacgcguuga acccccucua agaucugugc uggaacaaac aaaacugaag aaagaagaca     1080

ucuacgcagu agaaaucguc ggaggggcaa cucgaauacc ggccgucaaa gagaaaauca     1140

gcaaauucuu cgggaaggaa cucagcacca cccugaacgc agacgaagcg guaaccaggg     1200

gcugcgcgcu ccaaugcgcc auacugucac cagccuucaa aguacgagag uucagcauaa     1260

cagacguggu cccauaccca auaagccucc gauggaacuc accagcagaa gaaggcucga     1320

gcgacugcga aguauucagc aaaaaccacg cagcaccauu cuccaaaguc cucacguuuu     1380

accggaaaga accguucacc cucgaggcau acuacuccuc accccaagac cuccccuacc     1440

ccgacccagc caucgcacaa uucagcgucc aaaaggucac uccccagagc gacggcagua     1500

gcagcaaagu caaagucaaa guccgcguca acguacacgg gaucuucagc guaucaucag     1560

ccagccucgu ggaaguccac aagagcgagg aaaacgagga accaauggag accgaccaaa     1620

acgccaaaga agaagagaaa augcaagucg accaggaaga accccacgua gaagaacagc     1680

agcagcaaac ccccgcggaa aacaaagcag aauccgaaga aauggaaacc ucgcaagccg     1740

gcaguaaaga caagaaaaug gaccaaccac cccaagcaaa gaaagcaaaa guaaaaacgu     1800

ccacaguaga ccugccaaua gagaaccaac uacuuuggca aauagaccga gaaaugcuaa     1860

acuuauacau cgagaacgaa gggaaaauga ucaugcaaga uaaacuagaa aaagaaagaa     1920

acgaugccaa aaacgcaguc gaagaguacg uuuacgagau gcgggacaaa cuaagcggcg     1980

aguacgagaa guucgucucc gaggacgacc gcaacagcuu cacacugaaa cucgaagaca     2040

ccgaaaacug gcuauacgaa gacggcgaag accaaccaaa gcaaguauac gucgacaagc     2100

ucgcggaacu caaaaaccuc ggccaaccaa uaaaaauccg guuccaagaa agcgaggaga     2160

gaccaaagcu auucgaagaa cucggaaaac aaauccagca auacaugaaa auuauaucaa     2220

guuucaaaaa caaagaagau caauacgauc aucuggacgc cgcagacaug acaaaaguag     2280

aaaaaucgac caacgaagca auggaaugga ugaacaacaa auuaaaucug caaaacaaac     2340

aaagccuaac cauggacccc guaguaaaau caaaagagau cgaagccaaa aucaaagaac     2400

ucaccuccac augcagcccc aucauaagca aacccaagcc caaagucgaa ccacccaaag     2460

aggaacagaa aaacgcagaa caaaacggcc ccgucgaugg acagggcgau aaccccggac     2520

cgcaagccgc cgaacaaggc acggacacag ccgugcccuc agacagcgac aagaaacuac     2580

cagaaaugga caucgacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  7106
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt9)

<400>  7106
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucagucgucg gaauagaccu cggauuccuc aacugcuaca      120

uagccguagc acgcuccgga gguauagaga caaucgccaa ugaguacucc gacaggugua      180

cccccgcgug caucagccug ggcucccgca cucgcgccau cggcaacgcg gcgaaguccc      240

aaaucgucac caacgucaga aacacaaucc acggauucaa gaaacuccac ggacgauccu      300

ucgacgaccc cauaguccaa accgagcgca uacgccugcc cuacgaacua cagaaaaugc      360

caaauggcag cgccggcgua aaaguccgcu accucgagga ggaacgcccc uucgccaucg      420

aacaagucac aggcaugcua uuagcaaagc ucaaagagac cuccgaaaau gcacucaaga      480

aacccguggc agacugcgua aucagcauuc cguccuucuu cacagacgca gagcgacggu      540

cagucauggc agccgcacaa gucgccggcc ugaacugucu ccgacugaug aaugagacaa      600

cggccgucgc ccucgcauac ggcaucuaca aacaagacuu accuccgcuc gacgaaaaac      660

cgagaaacgu cgucuucauc gacaugggac acagcgcaua ccaaguccuc guaugugcau      720

ucaacaaagg aaaacuaaaa guucuugcca ccacauucga uccauaccuc ggaggccgca      780

acuucgacga agcacucguu gacuacuucu gugacgaguu caaaacaaaa uacaaaauaa      840

acgucaaaga aaacagccgc gcccuucucc gucuauacca ggagugcgaa aaacucaaga      900

aacucaugag cgccaacgcc agcgaucucc cacuaaacau cgaauguuuc augaacgacc      960

uggacgugag uuccaaaaug aaccgugccc aauucgagca acucugcgcc agcuuacuag     1020

caagaguaga accaccacuc aaagcgguca uggagcaagc caaucuccaa cgggaagaca     1080

ucagcuccau agagaucguc gggggagcaa cccgaauacc cgcuguaaaa gaacaaauaa     1140

cuaaauucuu ccuaaaagac auaagcacaa cccugaacgc cgacgaagca gucgcccgag     1200

gcugcgcacu ccagugcgcc auacucuccc ccgcguucaa aguacgcgag uucaguauca     1260

cagaccucgu accauacuca aucacccuac gcuggaagac aucuuucgaa gacggcuccg     1320

gagaaugcga agucuucugc aaaaaucacc ccgcccccuu uuccaaaguc aucacauucc     1380

acaaaaagga accguucgaa cucgaagcgu uuuacacgaa ccuccacgag guaccauacc     1440

ccgacgcgag aauaggauca uucaccauac aaaacguauu cccacaaucc gacggcgauu     1500

cauccaaggu caaagucaaa guaagaguca acauacacgg caucuuuuca gucgccagcg     1560

ccagcgugau ugagaaacaa aaccuugaag gcgaucacag cgacgccccc auggaaaccg     1620

aaacgagcuu caagaacgaa aacaaggaca acauggacaa gaugcaggua gaccaagagg     1680

aaggacacca aaaaugccau gcagaacaca cacccgagga agaaaucgac cacaccggag     1740

ccaaaacgaa gucugccguc agcgauaagc aggaccgucu caaccaaacc cucaagaaag     1800

gcaaaguaaa aagcauagac cuaccaaucc aaagcucacu cugccgccaa cucgggcaag     1860

accuccuaaa cuccuacaua gaaaacgaag gcaaaaugau caugcaagau aaacuagaaa     1920

aagaacgcaa cgacgccaaa aacgcagucg aagaauacgu cuaugacuuc cgagaccggc     1980

ucggaaccgu cuacgaaaaa uucauaaccc ccgaggaccu aucaaaacua agcgcugucc     2040

uagaagacac cgagaacugg cuauacgaag acggagagga ccaaccaaaa caaguauacg     2100

uagacaagcu ccaggagcuc aagaaauacg gccaacccau ccagaugaaa uacauggagc     2160

augaagaaag acccaaagca cucaacgacc ucggcaagaa aauccagcuc guuaugaaag     2220

uaauagaagc cuaccgaaac aaagacgagc gcuacgacca ccuagaccca accgaaaugg     2280

aaaaagucga aaaaugcauc agcgaugcca ugagcuggcu caacuccaag augaacgcgc     2340

agaacaaacu aucccucacc caagaccccg uaguaaaagu aucagaaaua gucgcaaaau     2400

cgaaagaacu ggacaacuuc ugcaacccaa ucaucuacaa gccgaaaccu aaagcagagg     2460

ugccagaaga caaaccaaaa gcaaauagcg aacacaacgg accaauggac gggcaauccg     2520

gaacagaaac caaaagcgau agcacaaaag acucauccca gcacacaaaa agcucagggg     2580

aaauggaggu cgacuaggga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  7107
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt9)

<400>  7107
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuaagcc uaguagcggc aaugcuccug cucuuaagcg      120

ccgcaagagc agaagaagag gacaagaaag aggacgucgg caccgucguc ggcauagacc      180

uaggcaccac guacagcugc gucgggguau ucaaaaacgg aagagucgaa aucaucgcca      240

acgaccaagg caacagaauc acacccagcu acguagccuu cacccccgaa ggagaacgcc      300

ucauaggaga cgcggccaaa aaccaacuca ccagcaaccc agagaacaca guauucgacg      360

caaaacggcu aaucggccgg accuggaacg accccagcgu ccaacaagac auaaaauucc      420

uccccuucaa ggucgucgag aagaaaacaa aaccauacau ucaagucgac auaggaggag      480

gucaaacgaa aacauucgca cccgaggaga uaagcgcaau gguacucacc aaaaugaaag      540

aaaccgcaga agcauaccuu ggaaagaaag ucacgcaugc cgucgucaca gucccagccu      600

acuucaacga cgcacaaaga caggcgacca aagacgccgg cacaaucgca ggacugaacg      660

uaaugcgcau aaucaacgag cccaccgccg cagccaucgc uuacgggcua gacaaacgag      720

aaggagagaa aaacauccuc guguucgacc uaggaggagg cacauucgac gucagccucc      780

uaacaaucga caacggagug uucgaagucg uagccaccaa cggcgacacg caccucggag      840

gagaggauuu cgaccaaaga guaauggaac acuuuaucaa acuauacaaa aagaaaacag      900

gcaaagacgu acgaaaagac aacagagccg ugcaaaaacu ucgacgugag guagaaaaag      960

ccaaacgagc acugucgagc caacaccaag caagaauaga aaucgagagc uucuacgaag     1020

gcgaagacuu cagcgaaacc cucacucgag caaaauuuga agaacuaaac auggaccucu     1080

ucagaagcac aaugaagcca guacagaagg ugcucgaaga cucagaccuc aagaaaagcg     1140

auauagacga aaucguccuc gucgggggca gcacccggau accgaaaauc caacaacucg     1200

ucaaagaguu cuucaacgga aaagaaccua gccguggaau caacccagac gaagccgucg     1260

cguacggagc cgcgguccag gcaggcgucc uaucaggcga ucaagacaca ggcgaccucg     1320

uccuacuaga cgugugccca cuaacacucg gaaucgaaac cgugggcgga gucaugacca     1380

aacuaauacc ccgcaacaca gucguuccca cgaagaaaag ccaaauauuc agcacggccu     1440

cagacaacca gcccaccgua acaaucaaag ucuacgaagg ggaacgccca cucaccaaag     1500

acaaccaccu ccugggcacg uucgaucuga caggcauacc acccgcgccc cgcggagucc     1560

cgcaaaucga aguaacauuc gaaauagacg ugaacgggau acugcgcguc acagccgaag     1620

acaaaggaac cggaaacaaa aacaaaauca caauaacaaa cgaccaaaac cgccuaacac     1680

cagaagaaau agaaagaaug guaaacgacg ccgaaaaauu cgcagaagag gacaagaaac     1740

uaaaagaacg cauagacacc cgaaacgaac ucgaaucaua ugcauacucc cucaaaaacc     1800

agaucggcga caaagaaaaa cuagggggca aacugagcuc cgaggacaag gaaacaaugg     1860

aaaaagcagu agaggagaaa aucgaauggc uggaaagcca ucaagacgca gacauagagg     1920

acuucaaagc caagaagaaa gaacuugaag agaucguaca accaauaauc ucaaaacucu     1980

acggcucggc aggaccacca ccgacaggag aagaagacac ggccgaaaaa gacgaacugu     2040

agggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  7108
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt9)

<400>  7108
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagccccaa gagaacuagc cguggggauc gaccucggga      120

caacauacuc cugcguaggc guguuccaac aaggaagagu cgaaauauua gcaaacgacc      180

aaggcaacag gaccacacca ucguacguag cguucacaga cacagaacgc cuagugggag      240

acgcagcaaa gucgcaagca gcacuaaauc cacacaacac ggucuucgac gcaaagaggc      300

uaauaggaag gaaguucgcc gacacaaccg uucaaagcga uaugaagcac uggccauuca      360

gagucgucuc ggaaggaggg aaaccaaaag ugcgggucug cuacagaggc gaagacaaaa      420

cauucuaccc agaagagauc uccagcaugg uacugagcaa aaugaaggaa acagccgaag      480

ccuaccucgg ccaaccaguc aagcacgcgg ucauaaccgu acccgccuac uucaaugaca      540

gccagcgcca agccacaaaa gacgccgggg caauagccgg acuaaacgua cuacgaauca      600

ucaacgaacc cacggcagca gcgauugcau acggccuaga ccgaaggggc gccggagaac      660

gcaauguccu gauauucgac cugggagggg gcacauuuga cgucuccgua cuaucaauag      720

acgcaggagu auucgaagug aaagcgacgg caggagacac gcaccuaggc ggcgaagacu      780

ucgacaaccg ucuagugaac cacuucaugg aagaguucag gcgaaaacac ggaaaagauc      840

ucagcggaaa caaacgcgca cuccgcaggc uaagaaccgc augcgaacgc gcaaaaagga      900

cccuaagcuc cucgacacag gccacccucg aaauagacuc ccuauucgaa ggagucgacu      960

ucuacacaag caucacccgc gcgcgauucg aagaacuaug cagcgaccuu uuccgcucaa     1020

cccuagaacc agucgaaaaa gcucuccgcg acgcaaaauu agacaaagca caaauccacg     1080

augucguccu aguaggcggc ucaacgcgca uaccaaaagu acaaaagcuc cugcaagacu     1140

ucuucaacgg gaaagaacua aacaaaucca uaaaccccga cgaagcgguc gccuacggcg     1200

cggcgguaca agcagcgguc cugaugggcg acaagugcga aaaagugcaa gaccuacuac     1260

uccucgacgu cgccccauua agccucggac uggagacggc aggaggagua augacaacac     1320

uaauccagcg aaacgcgacc auacccacaa agcaaaccca aaccuuuacc acguacucag     1380

acaaccaacc gggagucuuc auccaaguau augagggcga acgcgcaaug acaaaagaca     1440

acaaccucuu gggccgcuuc gaacucuccg gcaucccacc cgcgccccga ggcguaccgc     1500

aaauagaagu gaccuucgac auagacgcca acgggauacu aagcguaacc gcgacagacc     1560

ggucaaccgg caaagcgaac aaaaucacaa ucaccaacga caaaggacgg cuaagcaaag     1620

aagaaguaga acgcaugguc cacgaagccg aacaauacaa agccgaagac gaagcccaac     1680

gugaccgcgu cgcagcgaaa aacucacucg aagcccacgu guuccacguu aaaggauccc     1740

uccaagaaga aagccugcgc gacaagauac ccgaagaaga ccggagaaaa augcaggaca     1800

aaugccguga aguacucgcc uggcucgaac acaaccaacu agccgaaaaa gaagaauacg     1860

agcaucaaaa acgagaacug gaacaaauuu gcagacccau auuuucgaga cuguacgggg     1920

gcccaggcgu cccaggaggc ucaagcugcg gaacccaagc cagacaagga gaccccagca     1980

caggaccaau cauagaggaa guagacuagg gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  7109
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt9)

<400>  7109
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcacccc gcgaacucgc aguaggcauc gaccuaggca      120

ccaccuacuc cugcguaggc gucuuccaac aaggccgcgu agaaauacuc gccaacgacc      180

aaggcaaccg caccaccccc uccuacgucg cauucaccga caccgaacgc cucguaggcg      240

acgccgcuaa aucccaagcc gcccuaaacc cccauaacac cgucuucgac gccaaacgac      300

ucaucggccg aaaauucgca gacaccaccg uacaauccga caugaaacac uggccuuucc      360

aagucguauc agaaggagga aaaccaaaag uccgcgucug cuaccgcgga gaagacaaaa      420

cuuucuaccc cgaagaaaua uccagcaugg uccuaucaaa aaugaaagaa accgccgaag      480

cauaccucgg ccaacccguc aaacacgccg ucaucaccgu cccaaccuac uucuccaacu      540

cccaaagaca agccaccaaa gaugcaggcg ccauagccgg ccuaaaagua cuccccauca      600

ucaacgaggc caccgccgca gccaucgccu auggacuaga ucgccgcggc gccggcaaac      660

gaaacguccu gauauucgac cucggcggcg gcaccuucga cgucucagua cucagcauag      720

acgcaggcgu cuucgaagua aaagcaaccg caggagauac acaucucggc ggcgaagacu      780

ucgacaaucg acuugucaac cacuucaugg aagaguucag acgcaaacac ggcaaagacc      840

uaucaggcaa caaacgcgcc cuacgccgcc uacgaaccgc cugcgaaaga gccaaacgaa      900

cacccagcuc cucuacgcaa gcaacacucg aaauagacuc ccucuucgaa ggcgucgacu      960

ucuacaaauc caucacccga gcacgauucg aagaauuaug cuccgaccug uuccgcagca     1020

cccucgaacc cguagaaaaa gcccucagag acgcaaagcu ggacaaagcc caaauccacg     1080

acuucguccu cggaggcggc cuccacuccc acccccaagg cgcagaagua gcugcaggcc     1140

uccuacaacg acagggagcc gaacaagaac accaacccua aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  7110
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt9)

<400>  7110
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaaaaggac cggccgucgg aaucgaccuc ggcaccaccu      120

acagcugcgu cggcguguuc caacacggaa aaguggaaau caucgcaaac gaucaaggca      180

acaggaccac acccucguac guggcauuua ccgacaccga acgccucauu ggagacgcgg      240

ccaaaaacca gguagcaaug aaccccacca acaccgucuu cgacgcaaaa aggcuaaucg      300

gcagacgauu cgacgacgca gucguccaga gcgacaugaa acacuggcca uucauggugg      360

ucaaugacgc aggccgacca aaaguccaag ucgaauacaa aggcgaaacc aagagcuucu      420

accccgaaga aguauccagc auggugcuga ccaaaaugaa agaaauagca gaggcauacc      480

uaggaaagac cgucacgaac gcagucguga caguacccgc auacuucaac gacucacaac      540

gccaagccac aaaagacgcc ggaacaauag ccggccuaaa cguacuacgc auaauaaacg      600

aaccaacagc agcagcaauc gccuacggac ucgacaaaaa ggucggggcc gaacgcaacg      660

uccuaaucuu cgaucuagga ggagggacau ucgaugucag cauccugaca auagaagacg      720

ggauauucga agucaaaagc acagccggcg acacccaccu cggaggagaa gauuucgaca      780

accgcauggu caaccacuuu auagccgagu ucaagcgcaa gcacaagaag gacaucagcg      840

aaaacaaacg agccguacgc cgacuacgca ccgccugcga acgagcaaaa cgcacccugu      900

caagcagcac gcaagcgagc auagagaucg acagccucua cgaaggcaua gacuucuaca      960

cauccauaac gcgagcacgg uucgaagaac ucaacgccga ccuguuccgc ggcacccuag     1020

acccaguaga aaaagcccua cgagacgcca aacucgacaa aucacaaauc cacgacauag     1080

uucuggucgg cggcuccaca agaaucccua aaauccaaaa acuacuccaa gacuucuuca     1140

acggaaaaga acucaacaaa agcauaaacc ccgacgaagc aguggcguac ggagcagccg     1200

uccaagccgc gauccuaucc ggcgacaaga gcgaaaacgu ucaagaccuu cuccucuugg     1260

acguaacccc gcuaucauua ggaauagaaa ccgcgggagg aguaaugaca guacuaauca     1320

aaaggaacac uacaauaccg accaaacaaa cacaaaccuu cacgacauac ucagacaacc     1380

aaccaggcgu gcucauacaa gucuaugaag gagaacgcgc aaugacaaaa gacaacaacc     1440

uacucggcaa guucgaacuc acagggaucc cacccgcacc ccgcggagua ccacaaauag     1500

aaguaaccuu cgacaucgac gccaacggaa uccucaacgu cagcgccguc gacaaaucaa     1560

caggaaaaga gaacaaaauc acgauaacaa acgacaaagg gcgccugagc aaagaagaua     1620

ucgaacgaau gguucaggaa gccgagaaau acaaagcaga ggacgaaaag caacgcgaca     1680

aagucagcuc caaaaacucc cuagaaucau acgcguucaa caugaaagcg acggucgaag     1740

acgaaaaacu acaaggcaaa auuaacgaug aggauaaaca gaaaauacua gacaagugca     1800

acgaaaucau aaacuggcuc gacaagaacc aaacagcaga aaaagaagag uucgaacauc     1860

aacaaaaaga acucgaaaaa gucugcaauc ccauaauaac caaacuguac caaagcgcgg     1920

gcgggaugcc cggcgguaug ccgggaggcu uccccggagg cggcgcccca ccaagcggcg     1980

gcgcauccuc aggcccaacc aucgaagaag ucgacuaagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  7111
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt9)

<400>  7111
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaagcgcca gccgcgcagc cgcggcgagg cuaguaggcg      120

cagcggcaag uagaggaccg acggcggcaa gacaccaaga cucauggaac ggccugagcc      180

acgaggcguu cagacuggug agccgacgcg acuacgcaag cgaggccauc aaaggagcag      240

ucgucggaau cgaccuaggg acgacgaacu cgugcguagc agugauggag ggaaagcagg      300

cgaagguccu ggagaacgcg gaaggagcga gaaccacgcc aucagucgua gcauucaccg      360

cggacggaga gaggcucgug ggaaugccag cgaaaaggca ggcaguaaca aacccaaaca      420

acaccuucua cgcgacaaaa aggcuaauag guagaagaua cgacgaucca gaagugcaaa      480

aggacaucaa aaacguaccc uucaagauag uacgagccag caacggagac gcauggguag      540

aggcacaugg caagcuauau agcccgagcc agauaggggc guucguccuc augaagauga      600

aggaaacggc agagaacuac cugggacaca cggcaaagaa cgcggucaua acagugccag      660

cguacuucaa cgacagccaa cggcaagcga caaaggacgc agggcagaua aguggacuca      720

acguccuacg cgucauaaac gaaccaacag cggcugcccu cgcauacggg cucgacaaga      780

gcgaagacaa aguaauagca guauacgacc ugggcggagg cacauucgac auaucuauac      840

uagaaaucca gaaaggggua uucgaaguaa aguccacaaa cggcgacacg uuccuuggag      900

gggaagacuu cgaccaagcg cuauugcguc acaucguaaa ggaguucaag agagagacag      960

gaguagaccu cacaaaagac aacauggcgc ugcaacgagu aagagaagca gcagaaaaag     1020

cgaaguguga acuaagcucu agcguacaaa cagacauuaa ccucccauau cucacaaugg     1080

acaguucagg gccgaaacac cuaaacauga agcucacaag agcccaguuc gagggaauag     1140

ugaccgaccu aauccgcagg acaauagcgc cgugccaaaa ggcgaugcag gacgcagaag     1200

ugagcaagag cgacaucgga gaagucauau uaguaggggg aaugaccagg augccgaaag     1260

ugcaacagac ggugcaggac cuguucggca gagcaccgag caaggcagua aacccagacg     1320

aggcaguagc gaucggagcg gccauacaag ggggaguacu ugcgggagac guaacggacg     1380

uacuacuauu ggacgugacg ccauuaagcc uaggaauaga aacacuaggu ggcguguuca     1440

cuaaacucau caaucgaaac accacgauac ccacaaagaa aucacaagug uucagcacag     1500

cggccgacgg acagacccag gucgagauaa aaguaugcca aggagagcga gaaauggccg     1560

gggacaacaa acuacucggg caauucacac ugauaggaau accgccagca cccaggggag     1620

uaccccagau agagguaaca uucgacaucg acgcgaacgg aauaguccac gucagcgcaa     1680

aagacaaagg aacuggcagg gagcaacaaa uagugaucca aagcagcggc ggacugagca     1740

aggacgacau agagaacaug gugaaaaacg cggaaaaaua cgcggaggag gacaggagaa     1800

agaaagaaag gguagaagca guaaauaugg cggaagggau aauacacgau accgagacca     1860

agauggaaga guucaaggau caacucccag cggacgaaug caacaaauua aaagaagaaa     1920

uaagcaagau gagggaacua cuagcgcgca aagauagcga aacgggagaa aacauaagac     1980

aagccgcgag cagucuccag caggccagcc uaaaacuauu cgaaauggcg uacaagaaaa     2040

uggcaagcga aagagaaggg agcgggagca gcggaacagg agagcaaaaa gaagaucaga     2100

aagaagagaa gcaguaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  7112
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt9)

<400>  7112
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgacaaag aggcaggcgg aagcgacgga ccccgagaaa      120

cagccccaac auccgccuac uccagcccag caagaucacu cggcgacacc ggcaucacac      180

cacucucacc gucucacauc gucaacgaca ccgauucaaa cguauccgag caacaauccu      240

uccuaguagu cgucgccguc gacuucggga caaccuccuc cggcuacgca uauuccuuca      300

caaaagaacc cgaaugcauc cacgucaugc gccgcuggga aggaggagac cccggcguau      360

ccaaccagaa aacgcccacu accauccuac uaacccccga acgaaaauuc cacuccuucg      420

gcuacgcugc ccgagacuuc uaccacgacc ucgacccaaa cgaagccaaa caauggcucu      480

accuagaaaa guucaaaaug aaacuucaua ccacaggcga ccucaccaug gacaccgauc      540

uaaccgccgc aaacggcaag aaagugaaag cucuugaaau cuucgccuac gcccuucaau      600

acuucaaaga acaagcacua aaagaacucu ccgaccaagc aggcucagag uucgaaaacu      660

ccgacguucg cugggucauc acaguccccg caauauggaa acaacccgcc aagcaauuca      720

ugcgacaagc agcauaccaa gccggucucg caagcccaga aaauucagaa caauuaauca      780

uagcacucga acccgaagcc gcguccauau acugccgcaa acuucgccuc caccaaauga      840

uagaacucuc cucaaaagcc gcugucaacg gguacuccgg uagcgacaca gucggcgccg      900

gcuucacaca agccaaggag cacauacgcc gcaaccgcca aucgcgaaca uuccucgucg      960

agaacgucau cggagaaauc uggucagaac ucgaagaagg cgacaaauac gugguagucg     1020

acagcggcgg cggaaccgug gaccuaaccg uccaccagau acgccugcca gaagggcacc     1080

uuaaagaauu guacaaagcc acaggaggac ccuacggauc auuaggaguc gacuacgagu     1140

ucgaaaagcu gcucuacaaa aucuucggcg aagauuucau ugaacaauuc aaaauaaaac     1200

gccccgccgc augggucgau cugaugauag ccuucgaauc acguaaacgc gcagccgcuc     1260

ccgaccgaac caauccacuc aacaucaccc uacccuucuc auucaucgac uacuauaaga     1320

aauuccgcgg gcacuccguc gaacaugcuc uccgaaaauc aaacgucgau uucgucaaau     1380

ggucauccca aggcaugcuc cgcaugucac cggacgccau gaacgcacua uucaaaccca     1440

cuauagacuc aauaaucgaa caccuacgcg accucuucca aaagcccgaa guaagcacag     1500

ucaaauuccu cuuccucgug ggcggguucg ccgaagcccc acuccuccaa caggccgucc     1560

aggccgcauu cggagaccag ugccguauca uaaucccaca agacguaggc cuaaccauac     1620

ucaaaggcgc aguccuauuc ggccuagacc ccgccgucau uaagguccgc cguucccccu     1680

uaacauacgg agucggcguc cuuaaccgcu augucgaagg aaaacaccca cccgaaaagc     1740

uccuagucaa ggacggcacc cgauggugca ccgacgucuu cgacaaauuc auauccgcag     1800

accaaagcgu ugcacucggc gaacuuguca aacgaucaua cacccccgcg aaacccucac     1860

aauuagucau agucauaaac aucuacuccu cagaacacga caacguuucc uucaucaccg     1920

accccggcgu aaagaaaugc ggaacccuca gacuggaccu caccggcaca uccggcacug     1980

ccguacccgc acgacgcgaa auacaaaccc ucaugcaguu cggcgacacc gaaaucaaag     2040

caacugccau cgacauagcc acaucaaaau ccguaaaagu aggaaucgac uuccuaaacu     2100

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  7113
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt9)

<400>  7113
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuagcagucc ccgaaauggg ccuacaaggc cucuacaucg      120

gcuccagccc cgaacguuca cccguacccu caccaccagg cucaccaaga acccaagaaa      180

guugcggcau cgccccacuc acgcccuccc aaucccccaa gcccgaaguc cgagcacccc      240

aacaggcuuc auucucuguc gucguagcaa uagacuucgg aaccaccucu agcggcuacg      300

cuuucucauu cgccagcgac cccgaagcca uccacaugau gcgcaaaugg gaaggaggag      360

accccggugu agcacaccag aaaaccccaa ccugccuacu ccucacaccc gaaggagccu      420

uccacagcuu cggcuacacc gcccgagacu acuaccacga ccucgacccc gaggaggcuc      480

gugacuggcu cuacuucgaa aaauucaaaa ugaaaaucca cuccgccacc gaccucaccc      540

ucaaaacuca acuagaagcg guuaacggaa aaacaaugcc cgcccuagaa guuuucgcac      600

acgcccugcg cuucuuccga gaacacgcac uccaagaacu ucgcgaacaa agcccgagcc      660

uuccugaaaa agacaccguu cgaugggucu ugacaguccc cgcaauaugg aaacaaccgg      720

cgaaacaauu caugcgagaa gcagccuacc uagccggacu gguaucccga gaaaacgccg      780

agcaacuacu caucgcacuc gaacccgaag cugcauccgu cuacugccgc aaacuacgcc      840

uccaccaacu ccucgaccug uccggccgcg caccaggagg cgguagauug ggugagcgac      900

gcaguauaga caguuccuuu cgacaagcac gcgaacagcu acgccgaagc cggcacuccc      960

gaacuuuccu uguagaauca ggcgucggcg aacucugggc cgaaaugcaa gcaggagaca     1020

gauacguagu ugcggacugc ggcggcggca ccguugaccu gacaguccac caauuagaac     1080

aaccacacgg cacucucaaa gaacuuuaca aagcauccgg cggacccuau ggcgccguag     1140

gagucgacuu agcauuugaa caacuccugu gcagaaucuu cggggaagac uuuauagcaa     1200

ccuucaaaag acaaagaccc gcagccuggg ucgaccuuac caucgcauuc gaagcacgga     1260

aacgaacagc cggcccacac cgagcaggag cccugaacau cagccuacca uucucauuca     1320

ucgauuucua ccggaaacaa cgcggccaca acgucgaaac agcccuccgg cgaagcagcg     1380

ucaacuucgu caaaugguca ucccaaggaa ugcuacgaau guccugcgaa gcaaugaacg     1440

aacucuucca accaaccguc ucgggcauca uccaacacau cgaagccuua cuagcccgcc     1500

cagaaguaca aggagucaaa cuccucuucc uagucggagg cuucgcagag uccgcagucc     1560

uacaacacgc gguucaggcc gccuuaggag cacgcggccu ccgagucgug guaccccacg     1620

acguaggccu cacaauccua aaaggcgccg uucucuucgg gcaagcuccc ggcgucguac     1680

gcguacgccg cagcccacua accuacggcg uuggcguacu caaccgcuuc gucccgggaa     1740

gacacccacc cgaaaaacuc cuaguccgag acgguagacg cuggugcacc gacgucuuug     1800

aaagauucgu ggccgccgaa caaucagucg cccucggcga agaaguccga cgcagcuacu     1860

gccccgcacg ccccggccaa cgacgcgucc ucaucaaccu auacugcugc gcagcagaag     1920

acgcacgcuu uauaaccgac cccggcgucc gaaaaugcgg cgcacucuca cucgaauuag     1980

aacccgcaga cugcggucaa gacaccgccg gagccccgcc cggaagacga gaaauccgcg     2040

ccgcaaugca auucggcgac accgaaauca aagucacagc cgucgauguc uccacaaacc     2100

gaagcguaag ggccucgaua gacuuccuaa guaacuaggg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  7114
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt9)

<400>  7114
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaagagaaa ugacaauccu uggcuccgcc gugcuaaccc      120

uccuacuagc cgguuaccuc gcccaacagu accuaccccu ccccacccca aaagucaucg      180

gaaucgaucu cggcaccacc uacugcucag ucggcgucuu cuuccccggc accggaaaag      240

uaaaaguuau accggacgaa aacggccaca ucuccauccc cucaaugguc uccuucaccg      300

acaacgacgu cuacgucggc uacgaaagcg uggaacucgc cgacuccaac ccccaaaaua      360

caauauacga cgccaaacgc uucaucggca aaaucuucac cgccgaagaa cucgaagccg      420

aaauaggccg cuacccuuuc aaagugcuca acaaaaacgg cauggucgag uucuccguca      480

ccagcaacga aacaauaaca guaucgccag aauacgucgg cucccgccuc cuccuuaaac      540

uaaaagaaau ggcagaagcc uaccuaggca ugcccgucgc caacgcagua aucucagucc      600

cagccgaguu cgaccuuaaa caaaggaacu ccaccaucga agcagcuaac cucgccggcc      660

ugaaaauccu ccgagucauc aacgaaccca ccgccgcggc cauggcauac ggacuucaca      720

aagccgacgu cuuccacguc cucguaaucg accugggcgg cggcacccua gacgucagcc      780

uucucaacaa acagggaggc auguuccuca cacgcgcgau gucaggaaac aacaaacuag      840

gaggccagga cuucaaccaa cgccuacucc aauaccuaua caaacaaaua uaccaaaccu      900

acggauucgu uccaucccga aaagaagaaa uccacagacu ccgacaagca guagaaaugg      960

uaaaacucaa ccuaacccua caccaauccg cacaacuaag cguccuccuu acaguagaag     1020

aacaagaccg aaaagaacca cacuccuccg acaccgaacu ccccaaggau aagcuaucca     1080

gcgcugacga ccacagagua aacuccgguu ucggccgugg ccucagcgac aagaaaucug     1140

gugaaucaca gguccuauuc gaaaccgaga uaucccgaaa acucuucgac acccucaacg     1200

aagaccucuu ccagaaaauc cucgucccca uccaacaagu ccucaaagaa ggccaccucg     1260

agaaaacaga aaucgacgaa gucguacucg uaggaggcuc cacacgcauc ccccgcaucc     1320

gacaaguaau ccaagaguuc uucggcaaag accccaacac cucaguagac ccugaccugg     1380

ccgucguaac cggagucgcc auccaggccg gaauugaugg cggauccugg ccccuacaag     1440

ugagcgcccu cgaaauccca aacaaacacc uccagaaaac aaacuuuaac ugaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  7115
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt9)

<400>  7115
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgcaauag gcguccaccu aggcugcacc agcgccugcg      120

ucgccgucua caaagacggc agagcaggcg uagucgccaa cgacgccgga gaccgcguca      180

ccccagcagu cgucgccuac agcgagaacg aagaaaucgu ggggcucgca gccaaacaau      240

cccgcauccg aaauaucucc aacacaguca ugaaaguaaa acaaauccua ggacgcaguu      300

cgucagaucc ccaggcccaa aaauacauag ccgaaucaaa augccuagua auagagaaaa      360

acggcaaacu ccgauacgaa aucgacaccg gugaagaaac aaaauucgua aacccagaag      420

acgucgcacg ccuaauauuc agcaagauga aagaaaccgc ccacucugug cucggaagug      480

acgccaacga cguagucauc accguaccau ucgacuucgg cgaaaaacag aaaaacgccc      540

uaggcgaagc cgcaagagcc gccgguuuca acguccugcg acucauacac gaaccaagcg      600

ccgcgcuccu cgccuacggc aucggccaag acuccccaac cgggaagucc aacauccuag      660

uauucaagcu aggaggcacc agucuauccc uauccgucau ggaagucaac agcggcauau      720

accgcguacu cucaaccaac acagacgaca acaucggcgg agcccauuuc accgaaacac      780

uagcccaaua ccucgccucc gaguuccaac gcucuuucaa acacgacguc cgcggcaacg      840

cgcgcgccau gaugaaacua accaacagcg ccgaaguagc uaaacacuca cucucaacac      900

ucggcuccgc aaacugcuuu cuugacagcc uauacgaagg ccaagacuuc gacugcaacg      960

ucucaagagc cagguucgaa cuacuaugcu caccacucuu caacaaaugc aucgaagcca     1020

uacguggacu acucgaccaa aacggauuca cugccgacga caucaauaaa guaguacucu     1080

gcggaggauc uucacgaaua ccuaaacuac aacaacucau caaagaccuc uucccagccg     1140

ucgaacuucu uaacuccauc ccacccgacg aagucauccc caucggcgcc gccaucgaag     1200

ccggcauccu caucggaaaa gaaaaccuac uuguagagga cucccucaug aucgaaugcu     1260

ccgccagaga cauccuaguc aaaggcguag acgagagcgg cgccagccga uucaccgucc     1320

uauuccccuc cggaacacca cuaccagccc gacgccaaca cacacuacaa gccccaggau     1380

caauauccuc cgucugccuc gaacucuacg aaagcgacgg caaaaacucc gcaaaagaag     1440

aaaccaaauu cgcacaaguc guccuccaag accucgacaa gaaagaaaac ggccuccgcg     1500

acaucuuagc agugcucacc augaaacgcg acggcagccu gcacguaaca ugcacagacc     1560

aggaaaccgg caaaugcgaa gccaucucca uagaaaucgc cucauaagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  7116
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt9)

<400>  7116
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguaguag gacucgacgu agggagccaa uccugcuaca      120

uagccgucgc ccgcgccggu ggcaucgaaa ccaucgcaaa cgaguucagu gaccgaugca      180

cccccuccgu aauauccuuc ggaagcaaaa acagaaccau aggcguagcu gcuaaaaauc      240

agcaaaucac acacgcgaau aacacggucu caaacuucaa acgauuccac ggcagagccu      300

ucaaugaccc cuucauccaa aaagaaaaag aaaaccuauc auacgaccua guaccccuca      360

aaaacggagg cguaggaauc aaagucaugu acaugggaga agaacaccua uucagcguag      420

aacaaauaac ugccaugcua cucaccaaac ucaaggaaac cgcagaaaac ucacugaaaa      480

agccagucac cgacugcgug auaagcgucc ccucuuucuu caccgacgcc gaacgccgau      540

cgguccuaga cgcagcccaa auagucggcc uaaacugucu acgacuaaug aacgacauga      600

cagcaguggc ccugaacuac ggcaucuaua agcaagaccu gcccucgcuc gacgaaaaac      660

cacgcaucgu aguauucguc gauaugggcc acucagcauu ccaaguguca gccugcgcau      720

ucaacaaggg caaacucaaa gugcuaggca ccgccuucga ccccuuucuc ggaggcaaaa      780

acuucgacga aaagcuagug gaacacuucu gcgcagaauu uaaaaccaaa uauaaacucg      840

acgccaaauc caaaaucaga gcccugcuac gacucuacca agaaugcgaa aaacuaaaga      900

aacugauguc cuccaacuca accgaccugc cccugaacau cgaaugcuuc augaacgaca      960

aagacgucuc cgggaaaaug aacagaucac aauucgaaga acuuugcgcc gaacuacucc     1020

agaaaaucga aguaccacuc uacucccucc uggaacaaac ccaccuaaaa gucgaagacg     1080

uguccgccgu agaaauuguc ggcggcgcaa cacgcauacc ggccguaaaa gaacgaauag     1140

cgaaauucuu cggcaaagac aucuccacca cccuuaacgc agacgaagcc gucgcacgcg     1200

gcugcgcccu ccagugcgca auacucucgc cggccuucaa aguccgcgag uucuccguca     1260

cggaugccgu cccauucccg aucucccuga uuuggaacca cgacagcgaa gacacugaag     1320

gaguccauga gguauucagc cgaaaccacg cagcucccuu cagcaaagua cucacauucc     1380

uacgccgcgg accauucgaa cuggaagcgu ucuacaguga cccccaggga guaccguacc     1440

cggaagcaaa aaucggacgc uucguggugc aaaacguauc agcacaaaag gacggcgaga     1500

aaagccgcgu caaaguaaaa guaagaguaa auacgcacgg aaucuucaca aucucaacag     1560

ccucaauggu cgaaaaagua cccaccgagg aaaacgaaau gagcuccgaa gccgauaugg     1620

aaugccucaa ccaacgccca cccgaaaacc ccgauacaga caagaacguc caacaagaca     1680

auuccgaagc gggcacacaa ccccaggucc aaacagacgc acagcaaaca agccaguccc     1740

cacccucacc cgagcucacc ucggaagaga acaaaauacc cgaugccgac aaagcuaacg     1800

agaaaaaggu ggaccaacca cccgaagcca agaaacccaa aaucaaaguc guuaacguag     1860

aacuaccaau agaagccaau cuuguauggc agcucgggaa agaccuccug aauauguaca     1920

ucgaaacaga aggcaaaaug aucaugcagg acaaacucga aaaagaacga aacgaugcca     1980

aaaacgccgu cgaagaauac guauacgagu uccgagacaa acuaugcggc cccuacgaaa     2040

aguucaucug cgaacaagac caucaaaacu uccuccgacu ccucaccgaa acagaagacu     2100

ggcuauacga agaaggcgaa gaccaagcca agcaggcgua cguagacaaa cuagaggaac     2160

uaaugaaaau cgggaccccu guaaaaguac gauuccaaga agccgaagaa cgaccaaaaa     2220

uguuugaaga acugggacag cgccuccagc acuacgccaa gaucgccgca gacuuccgca     2280

auaaagacga aaaauacaac cauauagacg aaagcgaaau gaaaaagguc gaaaagagcg     2340

ucaacgaggu cauggaaugg augaacaacg ucaugaacgc ucaagccaag aaaagucuag     2400

accaagaccc cguagugagg gcgcaagaaa ucaaaaccaa aauaaaagag cugaacaaca     2460

caugugaacc agucgucacg caaccgaaac caaaaaucga aagcccgaaa cucgagcgca     2520

cacccaacgg acccaacauc gacaagaaag aagaagaccu agaagacaaa aacaacuucg     2580

gugccgagcc cccgcaccaa aacggugaau gcuaucccaa cgagaaaaac agcgugaaca     2640

uggaccuuga cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  7117
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt9)

<400>  7117
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagacaaag ugagacgaca acguccgcgu cggcggguuu      120

gcugggcacu cguggcaguc cuccuagcag acuugcucgc ccuaagcgau acccuagcag      180

ugaugucugu agacuuagga ucggaaucga ugaaaguagc caucgucaaa ccgggagugc      240

caauggaaau cguacuaaac aaagaaucac gcaggaaaac ccccgugauc gucacgcuga      300

aagagaauga gcgauucuuc ggcgauuccg cagcauccau ggcgaucaaa aacccgaagg      360

caacacugag auacuuucag caccuccucg gaaaacaggc agacaaccca cacguagccc      420

ucuaccaagc acgcuucccc gagcacgaac uaacauucga cccccaacgc caaaccgugc      480

acuuccaaau cagcagucag cuccaauuua gcccagaaga gguacucgga augguacuca      540

acuacuccag gagccucgcu gaagauuuug ccgaacagcc cauaaaagac gcagucauaa      600

caguacccgu cuucuucaac caagccgaaa gacgagcggu acuccaagca gcaagaaugg      660

ccggccucaa gguccuucaa cugaucaacg acaacacagc gacagcacuc uccuacggag      720

uauucagaag aaaagacaua aacaccacag cacagaacau cauguucuac gacaugggaa      780

gcggaaguac uguuugcaca auaguaaccu accaaauggu aaagaccaaa gaggcaggaa      840

ugcaaccaca acuucaaaua cgaggggucg gcuuugacag gacucuagga ggacuggaga      900

uggaacuccg gcuucgagaa cgccuagcag gacucuucaa cgaacaacga aagggccaga      960

gagccaaaga cguacgagaa aauccacgag caauggccaa acuccuaaga gaagcgaacc     1020

gacucaaaac gguccuaagc gcaaacgcgg accacauggc ccaaaucgaa ggacuaaugg     1080

acgacguuga cuucaaagcc aaaguaacac gaguagaguu ugaagaacuc ugcgccgacc     1140

ucuucgaacg agugccagga ccgguacaac aagcacucca gagcgcagaa augucccuag     1200

acgaaaucga gcaagugauc cuaguaggag gcgcaacccg gguaccacgc guacaagaag     1260

uauuacugaa agcgguggga aaagaagagu uagggaaaaa cauaaacgcc gacgaagccg     1320

cagcaauggg agcaguauac caagccgcgg cccucagcaa agccuucaaa guaaaacccu     1380

ucguagugcg ggacgcaguc guauacccaa uacuggugga guuuaccaga gaagucgaag     1440

aggaacccgg cauccacagc cuaaaacaca acaaaagagu ccuguucucc aggaugggac     1500

ccuacccaca acgcaaggug auaacauuca accgauacag ucacgacuuu aacuuccaca     1560

uaaacuaugg ggaccugggc uuccuaggac ccgaggaccu ccgcgucuuc ggaucccaaa     1620

accuaacaac cguaaaacuc aaaggaguag gagacucuuu caaaaaguac cccgacuacg     1680

aaucaaaggg gauaaaagcc cacuuuaacc ucgacgaaag ugggguccuc agccuggacc     1740

gcguagaguc ggucuucgaa acacucgucg aagacagugc cgaagaagaa ucaacccuaa     1800

cgaaacuagg caacacaaua ucaagccucu ucggaggagg cacaacaccu gacgccaaag     1860

aaaacggaac agacaccgua caagaagaag aggaaagccc cgcggaggga ucaaaagacg     1920

aaccaggcga acagguggaa cucaaagaag aagcggaagc cccagucgag gauggaagcc     1980

aacccccacc acccgaaccg aaaggcgacg caacaccgga aggcgaaaag gccaccgaga     2040

aagaaaacgg ggacaaguca gaagcccaaa agccaaguga aaaagccgaa gcaggcccag     2100

aaggaguagc cccggcccca gaaggagaga aaaagcagaa acccgccagg aaacgccgaa     2160

ugguggagga gauaggcguc gaacucguag uacuggaucu accagaccuc cccgaagaua     2220

agcuagcaca aagcgugcaa aaacuccagg accucacccu gcgcgacuua gaaaaacaag     2280

agagagagaa agcagcaaac agccuggagg ccuucaucuu cgaaacacaa gacaagcugu     2340

accagcccga auaccaagaa gugagcacgg aagaacaaag agaagagauc uccggcaagc     2400

uauccgcagc cagcacgugg cucgaagacg aaggaguagg ggccacaaca guuaugcuca     2460

aagaaaaauu agcagaacua agaaagcuau gccaaggacu auuuuucaga guggaagaga     2520

gaaagaaaug gccggaaagg cucagugccc ucgacaaccu acucaaccau uccagcaugu     2580

uccugaaggg cgcaaggcua auaccagaaa uggaccaaau auucacagaa guagaaauga     2640

ccacucucga gaaaguaaua aacgagacau gggcguggaa aaacgcaacc cucgcagaac     2700

aagcgaagcu gccagccacg gagaagccgg uucuacucag caaggauaua gaagcaaaga     2760

ugauggcacu agacagagaa guccaguacc uguuaaacaa agcaaaauuc acaaaaccac     2820

gcccaaggcc gaaagacaaa aacggaacac gagcagaacc accacugaac gcgucagcuu     2880

cagaccaagg agaaaaagua auacccccag cagggcaaac cgaggacgca gaaccaauca     2940

gugaaccaga gaaaguugag acgggaagcg aaccaggaga cacggaaccc uuagaauuag     3000

gaggcccagg cgcagaacca gaacaaaaag agcaaagcac uggccaaaag cguccccuca     3060

aaaacgacga gcuaugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  7118
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt9)

<400>  7118
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaagaga cgcaaacgca agaucaaccg auggaggagg      120

aagaagugga aaccuucgcg uuccaggcag aaaucgcgca acugaugagc cucauaauca      180

acacguuuua cagcaacaaa gaaauauucc ugcgcgagcu aauaagcaac agcagcgacg      240

cacucgacaa gauacguuac gaaucccuaa cggacccgag caaacuagac agcgggaagg      300

aacuacacau caaccucauc cccaacaagc aggaccgaac ccugaccaua gucgacaccg      360

gaauagggau gacgaaagca gaccucauca acaaccucgg aacgaucgcc aaaagcggca      420

cgaaggcuuu cauggaagca cuacaagcgg gcgccgacau aaguaugaua ggccaauucg      480

gaguaggauu cuacagugcc uaccuagugg cagagaaagu caccguaaua acaaaacaca      540

acgacgacga acaauacgcc ugggaaagca gcgccggggg cuccuuuaca guaagaacag      600

acaccggaga accaaugggc cgcggaacaa aaguaauacu ccaccuaaaa gaggaccaaa      660

cagaauaccu cgaggaaaga cgaauaaagg agaucgucaa aaagcacagc caauucauag      720

gauacccaau aacgcuauuc guggaaaaag aacgagacaa agaaguguca gacgacgaag      780

cggaggaaaa agaggauaag gaagaagaga aagagaaaga agaaaaagaa agcgaagaca      840

agccagaaau cgaggacgua gggucggacg aagaggagga aaagaaagac ggcgauaaga      900

aaaagaaaaa gaaaaucaaa gaaaaguaca ucgaccaaga ggagcuaaac aaaacaaaac      960

cgaucuggac acgaaaccca gacgacauca cgaacgagga auacggcgag uucuacaaau     1020

cacucacaaa cgacugggaa gaccaucuag caguaaagca cuucagcguc gaaggccaac     1080

uggaguucag agcucuccug uucguaccca ggcgcgcccc cuucgaccuc uucgaaaaca     1140

gaaagaagaa aaacaacaua aaauuauacg uaagacgagu auucauaaug gacaacugcg     1200

aagaacugau cccggaauac cucaauuuca uccgcggagu cguagacagc gaggaccuac     1260

cacuaaacau aagcagagag augcuacagc agaguaaaau ccuaaaagua auacggaaaa     1320

accuugucaa aaagugccug gagcuauuca ccgaacuugc agaggacaaa gaaaacuaca     1380

agaaguucua cgagcaguuc agcaagaaua uaaaacuagg cauacacgaa gacucacaga     1440

accgcaagaa acuaagcgaa cuccugagau acuacaccag cgccagcggg gacgagaugg     1500

ucagccuaaa agacuacugc acaagaauga aagaaaacca aaaacacauc uacuauauca     1560

cgggagaaac aaaagaccag gucgcgaacu cagccuucgu cgagcgacuc cgcaaacacg     1620

ggcucgaagu aaucuauaug auagagccca uugacgagua cugcguacag caacuaaaag     1680

aguucgaagg aaaaacccuc guaagcguca cgaaagaagg ccuagaacug cccgaagacg     1740

aagaggagaa aaagaaacaa gaagaaaaga aaacaaaauu cgaaaaccug ugcaaaauca     1800

ugaaagacau ccuggagaag aaaguggaga aaguagucgu aagcaaccgc cuaguaacga     1860

gcccaugcug cauagucaca agcacauacg gauggacggc gaacauggag cgaauaauga     1920

aagcccaagc ccugcgagac aacagcacaa ugggauacau ggcggccaaa aagcaccuag     1980

aaaucaaccc cgaccacucc aucaucgaaa cacucagaca aaaagccgaa gccgacaaaa     2040

acgacaaaag cguaaaggac cuggugauac uccuuuacga aaccgcccug cucucaagcg     2100

gcuucucccu ggaggaccca cagacccacg cgaacagaau cuacagaaug auaaagcugg     2160

gccuaggaau agacgaagac gacccaacag ccgacgacac auccgcagcc gucaccgaag     2220

aaaugccacc ccuagaaggg gacgacgaca caagcagaau ggaagaagua gacuaaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  7119
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt9)

<400>  7119
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucaucaa aacuagacuc cggcaaaggc cuacacauaa      120

accucguccc caacaaacaa aaccaaaccc ucaccaucgu agacacacgc aucggcauga      180

ccaaaaccga ccucaucaac aaccucggaa ccgucaccaa auccggcaca aaagccuuca      240

uggaagcccu ccaagcagac gcagacauau ccaugaucgg ccacuucgga guaggcuucu      300

acuccgccua ccucgucgcc aaaaaaguca ccgucaucuc aaaacacaac aacgacgaac      360

aauacaccug ggaauccucc gcaggaggca gcuucaccgu ccgcaccgac gaauaaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  7120
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt9)

<400>  7120
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaggaag uacaccacgg agaagaggaa gucgaaaccu      120

ucgccuucca agcggaaauc gcccaacuaa ugagcuugau aauaaacacg uucuacucca      180

acaaagagau auuccugcgg gagcuaauau cgaacgccag cgacgcccua gacaagauca      240

gguacgaguc ccucaccgac cccagcaaac uagacucggg caaggaacug aaaaucgaca      300

uaaucccgaa cccgcaagag cgcacccuca cccuagugga cacgggaaua ggcaugacca      360

aagcagaccu cauaaacaac cucggcacca uagccaagag cggaaccaag gccuucaugg      420

aagcacugca agcaggagca gacauaagua ugaucgggca auuuggcgua ggguucuacu      480

cagcguaccu cgucgccgaa aaaguaguag ucauaacgaa acacaacgac gacgagcaau      540

acgcguggga gucaagcgca ggagggagcu ucaccguacg ggcagaccau ggcgaaccca      600

uaggcagagg caccaaagua auccuccacc uaaaggaaga ccaaacagag uaccuagaag      660

aacggagagu aaaagaaguc gucaagaaac acucccaauu cauaggcuau cccaucacac      720

uauaccucga gaaagaacga gaaaaagaaa uauccgacga cgaagccgaa gaagaaaaag      780

gggaaaaaga agaggaagac aaagacgacg aagaaaagcc caaaauagaa gacguuggcu      840

cggacgagga ggacgacagc ggcaaagaca agaaaaagaa aacgaagaaa auaaaagaga      900

aauacaucga ucaagaagaa cucaacaaaa ccaaaccgau cuggacacgg aaccccgacg      960

auaucacgca agaggaguac ggcgaguucu acaaaucacu aacgaacgac ugggaagacc     1020

accucgcggu caagcacuuc aguguggaag gccaacuaga guuccgagcg cuauuguuca     1080

ucccaagacg cgcacccuuc gaccucuucg aaaacaaaaa gaagaaaaau aacauaaaac     1140

uguacguacg acggguguuc aucauggaca gcugcgacga auugauaccg gaauaccuga     1200

acuucauccg aggagucgug gacucagaag accucccacu aaacaucucc cgagaaaugc     1260

uucaacagag caaaauccua aaagugauca ggaaaaacau cguaaagaaa ugcuuagaac     1320

uauucagcga acuagcagag gacaaagaaa acuacaagaa auucuacgaa gccuucagca     1380

aaaacuugaa acuaggcaua cacgaagaca gcacgaaccg aaggcgcuug uccgaacuac     1440

uacgcuacca cacgucccag agcggcgacg agaugaccag ccugagugaa uacgugagcc     1500

gcaugaaaga aacgcagaaa agcauauacu acauaacagg cgaaagcaaa gaacaaguag     1560

cgaacagugc cuuugucgaa agaguacgaa aacgcggauu cgaggucgua uacaugacgg     1620

aaccaauaga ugaguacugc guccaacaac uaaaagaguu cgacgggaaa agccuaguca     1680

guguuacgaa agagggccuc gaacuacccg aagacgagga ggagaaaaag aaaauggaag     1740

aaagcaaagc aaaauucgaa aaccugugca agcucaugaa agaaauauug gacaagaaag     1800

ucgaaaaagu aacgaucucg aaucgacucg uaucaucccc cugcugcaua gucacgagca     1860

cauacggaug gacagcgaau auggagcgga ucaugaaggc acaagcccua cgcgacaaca     1920

gcaccauggg cuacaugaug gcgaagaaac accucgagau aaacccagac cacccgaucg     1980

uggagacgcu aagacagaaa gcagaagccg acaaaaacga caaagccgua aaagaccuag     2040

uaguacugcu auucgaaaca gcccugcuca gcagcggauu cucacucgaa gacccgcaaa     2100

cccacagcaa ccgaaucuac cgcaugauca agcucggacu cggcaucgac gaagacgaag     2160

uagccgccga agaaccgaac gcagccgucc cugacgagau accgccccuc gaaggcgacg     2220

aggacgcaag ccgaauggag gaaguagacu aaggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  7121
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt9)

<400>  7121
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgagccuuau ggguccucgg acucugcugc gugcuacuga      120

ccuucggcag cguaagagca gacgacgagg ucgacguaga cggcacggua gaggaagacc      180

ucggcaaauc gcgagaaggc ucacgcacag acgacgaagu aguccagcga gaagaagaag      240

cgauacaacu ugacgggcug aacgcgagcc agauccgcga acucagggag aaaagugaaa      300

aauucgcauu ucaggcagaa guuaacagga ugaugaagcu aaucauaaau ucccuguaca      360

aaaacaaaga gaucuuccua cgggaacuaa uaucaaacgc cagcgacgcu cuagacaaaa      420

ucagacuaau aagccuaaca gacgaaaacg cacuaagcgg aaacgaagaa uugacaguca      480

aaaucaagug cgacaaagag aaaaaccugc ugcacgucac cgacacaggc gugggcauga      540

cccgagagga acucgucaaa aaccugggaa cgauagcaaa gucagggacc agcgaguucc      600

ucaacaaaau gacagaagcc caggaggacg ggcagagcac gagcgaacug auagggcaau      660

ucggaguagg auucuacagc gcguuccugg uagcggacaa agucauaguc accagcaaac      720

acaacaacga uacccagcac aucugggaga gcgacaguaa cgaauuuagc guaaucgcag      780

acccucgagg caacacacua gggcgaggga ccacaauaac acugguacua aaggaagaag      840

ccagugacua ccucgagcua gauaccauca agaaucucgu aaagaaauac ucacaauuca      900

ucaacuuccc aaucuacguc uggagcagca aaacagaaac gguugaagaa ccuauggagg      960

aagaggaagc ggcaaaagag gaaaaggaag aaucagacga cgaggccgcc guggaagagg     1020

aagaagagga aaagaaacca aaaacgaaga aaguggagaa aacaguaugg gacugggaac     1080

ugaugaacga caucaagccc auauggcaaa gaccaagcaa ggaaguagaa gaagacgagu     1140

acaaggcguu cuacaaaagu uucuccaagg agucagacga ccccauggca uauauacacu     1200

ucacggcaga gggcgaaguc acauucaaga gcauacucuu cgugcccacc ucggcaccac     1260

gcggacuauu cgaugaguac gggagcaaga aaagcgacua cauaaaacua uacgucagga     1320

ggguauucau aacggacgac uuccacgaca ugaugcccaa guaccugaac uucgucaagg     1380

gaguagucga uagcgaugac cuaccccuga acguaagcag ggaaacccua caacaacaca     1440

aacuucucaa aguaauccgg aaaaagcucg ugaggaagac ccuagacaug auaaagaaaa     1500

uagcggacga caaauacaac gacacauucu ggaaagaguu cgggacaaac auaaaacuag     1560

gugugauaga ggaccacagc aacaggacga gacuggccaa acuccuacga uuccaaucaa     1620

gccaucaccc cacagacauc acgagccuag accaguacgu agaaagaaug aaggaaaaac     1680

aggacaaaau uuacuucaug gcagggucca gcagaaaaga ggccgaaagc ucccccuucg     1740

ucgaaaggcu gcucaagaaa ggguaugaag ucauauaccu aacagagcca gucgaugaau     1800

acugcauaca ggcacugcca gaguuugacg gcaagagauu ccaaaacguc gcaaaagaag     1860

gagugaaauu cgacgaaagu gagaagacca aagagagcag agaagccguc gagaaagagu     1920

ucgaaccucu ccucaacugg augaaagaca aagcgcuaaa agacaagaua gaaaaagcag     1980

ucguaagcca acgacucaca gaaagcccau gcgcgcuagu cgccucgcaa uacggauggu     2040

cagggaacau ggaaagaauc augaaagcgc aagcguacca aacugggaaa gacauaucca     2100

cgaacuacua cgccagccaa aagaaaacgu ucgaaaucaa ccccaggcau ccacugauaa     2160

gggauaugcu acgcagaaua aaagaagacg aggacgacaa aacaguccuc gaccucgcag     2220

ucguccucuu cgaaacggca acccuuagaa gcggcuaccu gcugccagac accaaagccu     2280

acggagacag gaucgagcga augcuacgac ucucacuaaa cauagacccg gacgcaaaag     2340

uagaggaaga accggaggag gagccagaag aaacagccga agauacaaca gaggacacgg     2400

aacaagacga agacgaagaa auggacguag guacagacga ggaagaagaa acagccaaag     2460

agagcacagc ggagaaggac gagcuauagg gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  7122
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt9)

<400>  7122
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgagaau uaagagcccu auuacucugg ggacgucguc      120

uccguccccu ccuccgcgca ccagcccuag cagccguacc cggcggcaaa cccauucucu      180

gcccaagaag aaccacugcc cagcuagggc cccgacgaaa ccccgcgugg ucgcuccaag      240

cuggacgacu cuucucaacc caaaccgcag aagacaaaga agaaccccuc cacagcauca      300

uaucuucaac agaauccguc caagguagca cauccaaaca cgaguuccaa gccgaaacca      360

agaaacuguu agauaucguc gcccgcuccc ucuacagcga aaaagaaguc uucauccgcg      420

aacugaucuc aaacgccagc gacgcccuag agaaacuacg ccauaagcua gucucagacg      480

gccaagcacu acccgaaaug gaaauucacc uccaaaccaa cgccgaaaaa ggcaccauaa      540

caauccaaga caccggaauc ggcaugaccc aagaggaacu cguaagcaac cucggcacua      600

ucgcgcgcuc agggucaaaa gcauuccuag acgcuuuaca aaaccaggcc gaggcuucau      660

ccaaaauaau cggccaauuc ggcguaggcu ucuacucagc cuucaugguc gcggaucgcg      720

ucgaagucua cucccgcagc gcagccccag ggagccuagg guaccagugg cucagcgacg      780

gcuccggcgu auucgaaauc gccgaagccu ccggagucag aacaggaacc aaaaucauaa      840

uucaccugaa aucugacugc aaagaguuca gcuccgaagc acgcguucga gacguaguca      900

caaaauacuc caacuucguc uccuucccac ucuaccucaa cggaagacgc augaacaccc      960

uccaggccau cuggaugaug gaccccaagg acguccguga auggcaacac gaagaguucu     1020

accgauacgu ggcacaagcc cacgauaaac cacguuacac ccuacacuac aaaaccgacg     1080

ccccacucaa caucagaagc aucuuuuacg uccccgacau gaaaccguca auguucgacg     1140

ucucccguga acuaggaucc uccgucgcac ucuacucacg caaaguccua auccaaacua     1200

aagccacaga cauccuuccc aaauggcucc gguucauacg cggcgucgug gacucagaag     1260

acaucccccu aaaccucucc cgcgaacuac uccaagaauc cgcgcuaauc cgaaaacuua     1320

gagacguacu acaacaacgg cuaaucaaau ucuucaucga ccagaguaag aaagacgccg     1380

aaaaauacgc uaaauucuuc gaagacuacg gacuauucau gcgagaaggc aucgucaccg     1440

ccaccgaaca agaagucaaa gaagauaucg caaaacuccu acgcuacgag ucuuccgccc     1500

uacccucagg acaacuuacc ucacuaagcg aauacgccag ccgcaugcgc gcgggcacac     1560

ggaauauaua cuaccuaugc gcacccaacc gacaucucgc cgaacacagc ccauacuaug     1620

aagccaugaa gaagaaagac acugaagucc uauucugcuu cgaacaauuu gaugagcuca     1680

cccuacuaca ccuccgggaa uuugacaaaa agaaacuaau auccgucgag accgacaucg     1740

ucguagacca cuacaaagag gaaaaauucg aggaccgcuc cccagcagcc gagugccuaa     1800

gcgaaaaaga aaccgaagaa cuaauggccu ggaugcgcaa cguucuaggc ucaagaguaa     1860

ccaacguaaa aguaacccua cgacucgaca cccaccccgc caugguaacc guacucgaaa     1920

ugggagcagc ccgccacuuc cuacgaaugc aacaacucgc caaaacacag gaggaacgag     1980

cccagcuccu acagccaaca cucgaaauca acccccgaca cgcacucauc aagaaacuca     2040

accaacuccg ggcauccgaa ccaggacucg cccagcuccu aguagaccag aucuaugaaa     2100

acgccaugau cgcugcaggc cuagucgacg acccaagagc aaugguugga cgacuaaacg     2160

aacugcucgu caaagcccuc gagcgccacu aaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  7123
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt9)

<400>  7123
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaaaucu ccucccuacc cacccaacua uucaaaugcu      120

gcuucugcga cuuccuaaaa gucaaaaugc acacaauguc cucaucccac uuauucuacc      180

ucgcacucug ccuccucaca uucaccucau ccgccaccgc aggccccgaa acccuaugcg      240

gcgccgaacu cgucgacgca cuccaauucg ucugcggcga ccgcggcuuc uacuucaaca      300

aacccacagg cuacggcucc uccucaagac gagcacccca aaccggcauc guagacgaau      360

gcuguuuccg aucaugcgac cuucgccgcc ucgaaaugua cugcgcaccc cucaaacccg      420

ccaaaucagc ccgcuccguc cgugcccaac gacacaccga caugcccaaa acccaaaaag      480

aaguccaccu caaaaacgcc ucccgcggcu ccgcaggcaa caaaaacuac cgcauguaag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  7124
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt9)

<400>  7124
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaucccca ugggcaaauc aaugcucguc cuccucaccu      120

uccucgccuu cgccuccugc ugcauagccg ccuaccgacc cuccgaaaca cucugcggcg      180

gagaacucgu cgacacccua caauucgucu gcggcgaccg aggcuucuac uucucccgac      240

ccgccucacg aguaucccgc cgcucccgcg gcaucgucga agaaugcugc uuccgcucau      300

gcgaccucgc ccuccucgaa accuacugcg ccaccccagc caaauccgaa cgagacgucu      360

ccaccccacc cacaguacuu cccgacaacu uuccccgaua ccccguaggc aaauucuucc      420

aauacgacac cuggaaacaa ucaacccaac gacuccgccg uggccucccc gcccuacucc      480

gcgcacgccg cggacacguc cuagcaaaag aacucgaagc cuuccgcgaa gccaaacgac      540

accgcccccu caucgcccuc cccacccaag accccgccca cggaggcgcc ccacccgaaa      600

uggccuccaa ccguaaauaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  7125
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt9)

<400>  7125
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccaccuccgc cuucggcccc gucgccuucu      120

cccucggccu ccuccucguc cuccccgccg ccuuccccgc ccccgucccc cccggcgaag      180

acuccaaaga cgucgcugcc ccccaccgcc aaccccuaac cuccuccgaa cgcaucgaca      240

aacaaauccg cuacauccua gacggcaucu cugcacuccg aaaagaaacc ugcaacaaau      300

cuaacaugug cgaauccucc aaagaagccc uagccgaaaa caaccucaac uuacccaaaa      360

uggccgaaaa agacggcugc uuccaauccg gcuucaacga agaaaccugc cucgucaaaa      420

ucaucaccgg ccuccucgaa uucgaagucu accucgaaua ccuacaaaac cgauucgaau      480

ccucagaaga acaagcccga gccguccaaa uguccaccaa aguccucauc caauuccucc      540

aaaaaaaagc caaaaaccuc gacgccauca ccacaccuga cccaaccacc aacgccucac      600

uccucacaaa acuccaagcc caaaaccaau ggcuccaaga caugacaaca caccucaucc      660

uccgcuccuu caaagaauuc cuucaauccu cccucagagc ccuccgccaa auguaaggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  7126
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt9)

<400>  7126
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuacucu ggcuacgcgg cuuccuacua gcaagcugcu      120

ggaucauagu aagaagcuca cccaccccag gaagcgaagg acacagcgcc gcgccagacu      180

gcccaucaug cgcacucgcc gcccucccca aagacguacc caacagccag cccgaaaugg      240

uagaagcagu gaaaaaacac auacuaaaca ugcuccaccu aaaaaagcga cccgacguaa      300

cccaacccgu cccaaaagca gcacuacuaa acgcaaucag aaaacuccac guagggaaag      360

ucggcgaaaa cggauacgua gaaaucgaag acgacauagg aaggcgcgcc gaaaugaacg      420

aacucaugga acaaacgucg gaaauaauca cauucgcaga aucagguacg gccagaaaaa      480

cccuacacuu ugagaucagc aaagaaggga gcgaccuaag cgucgucgaa agagcagagg      540

ucuggcuguu ccucaaaguu ccaaaagcca acagaacacg cacaaaagua acaauacgcc      600

uauuccagca acaaaaacac ccacaaggca gccuagacac cggagaagag gccgaggaag      660

uaggacuaaa aggagaacgg agcgaacuac uacuaagcga aaaagucgua gacgcccgca      720

aaagcacaug gcauguauuc cccguaagca gcuccauaca acgacuccua gaccaaggca      780

aaucaucacu cgacguaaga aucgcgugcg aacaaugcca agaaagcgga gccagccuug      840

uacuacuggg caagaaaaaa aaaaaagaag aggaaggcga agggaaaaaa aaaggcggcg      900

gagaaggagg cgccggagca gacgaagaaa aagaacaaag ccacagaccc uuccuaaugc      960

ugcaagcacg acagagcgaa gaccaccccc accgcagacg ccgacgcgga cucgaaugcg     1020

acggaaaagu aaacaucugc ugcaagaaac aauucuucgu cagcuucaag gacauaggau     1080

ggaacgacug gauaauagca ccgagcggcu accaugcaaa cuacugcgaa ggcgaaugcc     1140

caagccacau cgcaggcaca agcggaagca gccuaagcuu ccacagcacc gucaucaacc     1200

acuacagaau gcgaggacac agcccauucg ccaaccugaa aagcugcugc gucccgacga     1260

aacuaagacc aaugagcaug cuauacuacg acgacggcca aaacauaaua aagaaagaca     1320

uacaaaacau gauaguagaa gagugcggcu gcagcuaagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  7127
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt9)

<400>  7127
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccucc ccggccgagc acuaggcgcc gcaugccucc      120

uccuacucgc agccggaugg cuuggccccg aagcaugggg cuccccaaca ccaccuccca      180

cccccgcagc accaccccca cccccaccac ccggcucccc cggcggcagc caggacacau      240

gcaccucaug cggcggcuuc cgacgccccg aagaacucgg ccgcgucgac ggagacuucc      300

ucgaagccgu aaaacgccac auccuuuccc gccuccaaau gcgaggccga cccaacauca      360

cucaugccgu ccccaaagcc gccaugguca ccgcccuacg caaacuccac gccggcaaag      420

uccgagaaga cggccgcguc gaaauccccc accucgacgg ccacgccagc cccggcgccg      480

acggccaaga acgaguuucc gaaaucaucu ccuucgccga aaccgacggc cuugcaucca      540

gccgaguacg ccucuacuuc uucaucucaa acgaaggcaa ccaaaaccuc uucguaguac      600

aagccucccu uuggcucuau cucaaacucc uacccuacgu acuagaaaaa ggcucucgcc      660

gcaaaguaag agucaaaguc uacuuccaag aacaaggcca cggcgaccga uggaacaugg      720

ucgagaaacg cgucgaccua aaacgcuccg guuggcacac auucccccuc accgaagcaa      780

uccaagcccu cuucgaacga ggggaacgcc gccucaaccu agauguccaa ugcgacagcu      840

gccaagaacu agccgucguc cccgucuucg ucgaccccgg cgaggaaucc caccgacccu      900

ucgucgucgu ccaagcacga cucggcgacu cucgccacag aauacguaaa cgaggacucg      960

aaugcgacgg ccgcaccaac cucugcugca gacaacaauu cuucaucgac uuccgccuca     1020

uuggauggaa cgacuggauc auagcaccca cuggauacua cggcaacuac ugcgaaggcu     1080

ccugccccgc auaccucgca ggaguccccg gaagcgcauc cucuuuccac accgcaguag     1140

ugaaccaaua ccgcaugcgc ggccucaacc ccggaaccgu caacagcugc ugcaucccca     1200

ccaaacuuuc caccaugagc augcucuacu ucgacgacga auacaacauc guaaaacgag     1260

acguccccaa caugauagua gaagaaugcg gaugcgcaua aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  7128
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt9)

<400>  7128
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacuaaggg uacuccuccu caccgcccuc acacucugcc      120

acggauucaa ccucgacacu gaaaacgcaa ugacauucca agaaaacgcg cggggcuucg      180

gacaaucagu gguccagcug caagguagcc gcgucgucgu gggcgccccg caagagaucg      240

uagcagccaa ccagcgcggc ucucuauauc aaugcgacua cucaacuggc aguugcgaac      300

ccaucagacu acaaguccca gucgaagcug ucaacaugag ccuuggacua ucgcuagccg      360

caacaaccuc gccuccucaa cuccucgccu gcggcccaac cguccaccag accugcuccg      420

agaauaccua cgucaaaggc cucugcuuuu uguucggcuc uaaccugcgc caacaaccgc      480

aaaaauuccc ggaagcccug cgaggcugcc cccaggaaga cucagacaua gcuuuccuaa      540

uugacggguc cggcuccauc auaccccacg acuuccgucg aaugaaagag uucguaucaa      600

cuguaaugga acaacucaag aaaucuaaaa cgcuguucuc acucaugcaa uacagcgaag      660

aguucaggau ccacuucacc uucaaagagu uccaaaacaa cccaaaccca cgcucgcucg      720

ucaagccaau aacccaacuc cucggcagaa cccauacagc uacaggcauc cgaaaagucg      780

ucagagaacu cuucaacauc accaacggcg cccggaaaaa ugccuucaaa auccuuguag      840

ucaucaccga cggugaaaaa uucggcgauc cucuuggaua cgaagacgua auuccugaag      900

ccgacagaga aggagugauu cgauacguca ucggaguggg cgacgcauuc cgcagugaaa      960

agucccgaca agaacugaac accaucgccu ccaaaccucc ccgagaccac guuuuccaag     1020

uaaacaacuu cgaagcacuc aagaccaucc aaaaccaacu gcgcgagaaa auauucgcaa     1080

ucgaaggcac gcaaaccggg uccaguucau ccuucgaaca cgaaaugucc caggaaggau     1140

uuuccgcagc gaucacuucc aacggacccu uacuauccac agucggcucg uacgacuggg     1200

ccggcggcgu auuccuauac accagcaaag aaaaauccac cuucaucaac augacccggg     1260

ucgacagcga caugaacgau gccuaccucg gguaugcagc cgcaauuaua cuaaggaacc     1320

gcguucaauc ccucguacug ggagcacccc gcuaccagca cauaggccua guggcuaugu     1380

uccgucaaaa cacaggcaug ugggaaucca augccaacgu uaagggcacg caaauaggag     1440

ccuacuucgg cgccucucua ugcuccguag acguagacuc caacggaucc acagaccuag     1500

uacugaucgg cgcaccccac uacuacgaac aaaccagagg cggacaaguc ucaguguguc     1560

cacucccccg cggucgagca cgauggcaau gugaugccgu ccuauacggc gaacagggac     1620

aaccgugggg ccgcuuugga gcugcccuca ccguccucgg cgauguaaac ggugacaaac     1680

ucacugaugu agccauaggc gcccccggag aagaggauaa cagaggagcc gucuaccuau     1740

uccacggcac cucaggaagc gggaucagcc caucccacuc ccaacgcaua gcgggcucaa     1800

agcuaucgcc ucgccugcag uacuuuggcc aaagccucuc cggcggccaa gaccucacca     1860

uggacggucu aguagaccuc acaguaggag cccaaggaca uguacuccuc cuucgcucgc     1920

agcccguacu cagaguaaag gccaucaugg aauuuaaucc aagagaaguc gcccgaaacg     1980

uauucgaaug caacgaucag gugguuaaag guaaagaagc cggugaggua cgcguauguc     2040

uccacguaca aaaaucgacc cgggacagac uucgcgaagg acaaauccaa ucaguaguca     2100

ccuacgaccu cgcucuagac uccggucguc cccauucacg agccguguuc aacgaaacca     2160

aaaacucuac aagacgccaa acucagguac ucggcuugac acaaacuugu gagaccuuaa     2220

aacuucagcu gccaaacugu aucgaggacc ccgucucccc aaucguacug cggcuuaacu     2280

ucucucucgu cggcacaccc cuuuccgcgu ucgguaaccu gagacccguc cucgcagaag     2340

acgcccaacg acucuucacc gcacucuucc ccuuugagaa aaacugcggc aacgacaaca     2400

ucugccaaga ugacuuaagc auuacauucu cauuuaugag ccuagacugu cucguaguag     2460

gcggaccccg ggaauuuaac gucacuguaa ccgugcgcaa cgacggugaa gacuccuaca     2520

ggacgcaagu cacauucuuc uucccccucg acuuaagcua ccguaaaguc agcacccuuc     2580

agaaccagcg uucucaacga uccuggaggc uugcgugcga aucagcuagc ucaaccgagg     2640

ucuccggcgc gcucaaaucc accucaugcu ccaucaacca ccccaucuuc cccgaaaaca     2700

gcgaaguuac cuucaacaua accuucgacg uagacuccaa ggcaucacua ggaaacaaac     2760

uccuccucaa ggccaacgua accuccgaga auaacaugcc acgcacgaau aaaacagagu     2820

uccaauugga acuccccgua aaauacgcgg uauacauggu cgucacuucu cacggaguau     2880

cuaccaaaua ccuaaacuuu acagccuccg aaaacacaag ccgaguaaug cagcaucaau     2940

accaaguguc aaaccuggga caaagaucgc uaccuaucuc acucgucuuc cugguaccgg     3000

ucaggcuuaa ccaaacgguc auaugggacc gcccccaagu aaccuuuuca gaaaaccucu     3060

ccagcacaug ccacaccaaa gaaaggcucc caucacauag cgacuuccua gcagagcucc     3120

gcaaggcgcc cgucguuaac ugcuccauag cagugugcca acgcauccag ugcgacauac     3180

cauucuuugg cauccaggag gaguucaacg caacccucaa gggaaaccuc ucuuucgacu     3240

gguacauaaa aacuucccac aaucaccucc uaaucgucuc caccgcagaa auccucuuca     3300

acgacagcgu auucacccua cuaccaggcc agggagcguu cguccggagc caaaccgaaa     3360

ccaaagugga accauuugaa guacccaacc ccuuaccccu aaucgucggg uccucagucg     3420

gcggccuacu acuucucgcu uuaaucaccg ccgcccucua caaacuaggc uuuuucaaaa     3480

gacaauacaa agacaugaug uccgaaggag gcccacccgg ggccgaaccg caauaaggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  7129
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt9)

<400>  7129
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucagccuca aaacgcuccc cuuccuccua cuccuccacg      120

uccaaauauc uaaagccuuu cccgucuccu cuaaagaaaa gaacacaaaa acaguacaag      180

acuaccugga aaaauucuac caacucccau ccaaccaaua ccagucaacc cgcaaaaacg      240

gcaccaacgu aaucgucgaa aaacucaaag aaaugcaacg cuucuucgga cucaacguca      300

cugguaaacc aaacgaagaa acccucgaca ugaugaaaaa gccgagaugc ggcguaccag      360

acuccggcgg cuuuaugcuc acccccggaa acccgaaaug ggaacgcacc aaccucaccu      420

accgcauacg aaacuacaca ccccaacucu cugaagccga agucgaacgu gccaucaaag      480

acgccuucga acucugguca guagccuccc cacucauuuu cacacgaauc ucccaaggug      540

aagccgacau caacaucgcc uucuaccaac gagaccacgg cgacaauucc cccuuugacg      600

gcccaaacgg aauacuagcc cacgccuucc aacccgguca aggcaucggc ggcgacgccc      660

acuucgacgc agaagaaacc uggaccaaua ccuccgcaaa cuacaaccuc uuccucgucg      720

cagcccacga auuuggacac ucacucggcc ucgcacacuc uagcgacccc ggcgcccuca      780

uguaccccaa cuacgccuuc cgagaaaccu ccaacuacuc acucccgcaa gacgacaucg      840

auggaaucca agccaucuac ggccucuccu ccaacccaau ccaacccacu ggccccucaa      900

cccccaaacc cugugaccca ucccucacau ucgacgccau uaccacccuc cgcggggaaa      960

uccucuucuu caaagaucgc uacuucuggc gccgacaccc ccaacuacaa cgcgucgaaa     1020

ugaauuucau cucccucuuc uggcccuccc ucccuaccgg cauucaagcc gccuacgaag     1080

acuucgaucg cgaccuuauu uuucucuuua aaggcaacca auacugggcc cucucgggcu     1140

acgacauccu acaaggauac cccaaagaca ucuccaacua cggauucccc ucuuccgucc     1200

aagcuauaga cgccgccguc uucuaccgau ccaagacaua cuucuucguc aaugaccaau     1260

ucuggcgaua cgacaaccaa cgacaguuca uggaacccgg guaccccaaa uccauuuccg     1320

gagccuuccc aggcaucgaa uccaaagucg acgccgucuu ccagcaagaa cacuucuucc     1380

acgucuucuc aggcccccgc uacuacgccu ucgaccuaau cgcccaacgc gucacccgcg     1440

ucgcccgagg caacaaaugg cucaacugca gauacggaua aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  7130
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt9)

<400>  7130
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuguggc aaccccucgu ccucguccuu cuuguccucg      120

guugcuguuu cgccgcaccc cgccaacgac aguccacccu cguccucuuc cccggagacc      180

uccgcacaaa ccuaacugac cgccagcucg ccgaagaaua ucuuuaccgc uacggcuaca      240

cccgcgucgc agaaaugaga ggcgaaucca aaucucuggg gcccgcccuc cuccuccucc      300

aaaaacagcu cucccucccc gagaccggag aacuugacuc cgccacccuc aaagcaaugc      360

gaacaccacg cugcggcguc ccagaccucg gccgcuucca aacguucgaa ggcgaccuaa      420

aauggcauca ucacaacauu accuacugga uccaaaacua cuccgaagac cucccccgcg      480

ccguaauaga cgacgccuuc gccagagccu ucgcgcucug guccgccguc accccacuaa      540

cauucacccg cgucuacuca cgcgacgccg acauagugau ucaauucggu gucgcugaac      600

acggggacgg cuaccccuuc gacggaaaag acggccuacu ggcccacgca uucccacccg      660

gacccggaau ccaaggugac gcccacuuug acgacgacga gcuuuggucc cuaggaaagg      720

gcgucguagu cccaacacgc uucggaaacg cagacggcgc cgcuugccac uuccccuuca      780

uauucgaagg aagguccuac ucagcaugca ccaccgacgg ccgaucagac ggccucccgu      840

ggugcucgac cacagcgaac uacgacacag augaccgcuu cggcuucugc cccucagaac      900

gacuauacac ccaggacggc aacgccgacg gaaaacccug ccaauuccca uucauauucc      960

agggucagag cuacuccgcc uguacgacgg acggcagaag cgauggcuac cgcuggugcg     1020

caaccacagc gaacuacgac cgagacaaac uuuucgguuu cuguccaacc cgcgcagacu     1080

ccaccguaau gggcggcaac agcgccggag aacuaugcgu cuucccauuc accuuccucg     1140

gaaaagaaua cuccacuugu accucggaag gcagaggcga cggaagacuc uggugugcua     1200

caaccucaaa cuucgacucc gacaagaaau ggggcuucug ccccgaucaa ggcuacaguc     1260

uauuccucgu cgcagcccac gaguucggac acgcccucgg gcucgaccac uccuccguac     1320

ccgaagcgcu aauguaccca auguacaggu uuaccgaagg accaccccua cacaaagacg     1380

acgucaacgg aauccgccac cuuuacggcc cccgccccga acccgaaccu cguccaccca     1440

ccacaacaac accccaaccc accgcaccgc caaccguaug ucccacgggg cccccuaccg     1500

uccacccgag cgaaagaccc acagcaggcc cuaccggucc acccucagca ggacccacag     1560

gacccccuac ugccggcccc ucuacagcca cuacuguccc ccuaagccca guugacgacg     1620

caugcaacgu aaacauauuu gacgcaaucg ccgaaaucgg caaccaacuu uaccuauuca     1680

aagacgguaa auacuggcga uucuccgaag gacgcggaag ucgcccccag ggcccauucc     1740

uaaucgcaga caaauggcca gcccuaccga gaaaacuaga uucagucuuc gaagaaagac     1800

uaagcaagaa acucuucuuc uuuucuggcc gacaaguaug gguauacaca ggagccagcg     1860

uacuaggccc cagaagacuc gacaaacuag gccuaggagc agacguugca caaguaaccg     1920

gagcucuccg uuccggcaga ggcaaaaugc uauuguucuc uggccgcaga cuuuggcgcu     1980

ucgacgucaa agcucaaaug guagaccccc gauccgcauc cgaggucgac cgcauguucc     2040

ccggcguccc cuuagacaca cacgacguuu uccaguaccg agagaaagcc uacuucugcc     2100

aagaccgcuu cuacuggaga guaagcagca gguccgaacu caaccaagua gaccaagucg     2160

gauacguaac auacgacauc cuccaaugcc cagaagacug aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  7131
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt9)

<400>  7131
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggag uccucgccgc auuccuauuc cucuccugga      120

cccacugccg agcccuaccc cucccauccg gcggagacga agaugaccuc uccgaagaag      180

accuccaauu cgcagaacgc uaccuucgcu ccuacuacca cccaaccaau cucgcaggca      240

uccuaaaaga aaacgccgca uccucaauga ccgaacgccu ccgagaaaug caauccuucu      300

ucggccucga agucaccggc aaacucgacg acaacacccu cgacguaaug aaaaaaccua      360

gaugcggagu cccagacguc ggagaauaca acguauuccc ccguacccug aaauggucaa      420

aaaugaaccu cacguacagg aucguaaacu acacccccga caugacccau agcgaagucg      480

aaaaagccuu caaaaaagcc uucaaagucu gguccgacgu cacuccacua aacuucaccc      540

gucuccacga cggcauagcc gacaucauga uauccuucgg aaucaaagag cacggcgacu      600

ucuaccccuu cgacggaccc agcggucucc ucgcacacgc cuuccccccg ggccccaacu      660

acggcggaga cgcccacuuc gaugacgacg agaccuggac auccuccuca aagggcuaca      720

accucuuccu cgucgccgcc cacgaauucg ggcacucacu uggacucgac cauuccaaag      780

accccggagc ccucauguuc ccaaucuaca cauacaccgg caaaagucac uucaugcucc      840

ccgacgacga cguccaagga auucaaagcc ucuacggccc cggcgaugaa gaccccaacc      900

ccaaacaucc caaaacaccc gacaagugcg acccuucccu cagccucgac gcaaucaccu      960

cacucagagg cgaaaccaug auauucaaag accgauucuu cuggcgacuc cacccgcaac     1020

aaguagacgc cgaacuauuc cuaaccaaau ccuucuggcc agaacuaccu aaccgaaucg     1080

acgccgccua cgaacacccc agccacgacc ucaucuucau cuuccgcggc agaaaauucu     1140

gggcccucaa cggcuacgac auccucgaag gcuaccccaa aaaaauaucu gaacucggcc     1200

ucccaaaaga agucaaaaaa auauccgccg ccguccacuu cgaagacacc ggcaaaaccc     1260

uacucuuuag cggcaaccaa gucuggcgau acgacgacac gaaccacauc auggacaaag     1320

acuacccucg ccucaucgaa gaagacuucc caggaaucgg cgauaaagua gacgcgguuu     1380

acgaaaaaaa cggcuacauc uacuucuuca acggcccaau acaauucgaa uacuccauau     1440

gguccaaccg aauagucaga gugaugccag caaauucaau ccucuggugc uaaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  7132
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt9)

<400>  7132
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaccccca acacaaccga agacuacgac accaccacgg      120

aguucgacua cggcgacgcc acccccugcc aaaagguaaa cgaacgagcc uucggcgcac      180

aacuucuccc accccuguac ucccuagugu ucguaauagg ccucgucggc aauauccuag      240

ucguauuagu ccucguccaa uacaaacgcc ucaagaacau gaccucuaua uaccuacuca      300

accuagcaau cuccgaccuc cuuuuccugu ucacccuccc cuucuggauc gacuauaaac      360

ucaaagacga uugggucuuc ggagacgcca ugugcaaaau ccucuccggc uucuauuaua      420

ccggucucua cuccgaaauc uucuucauaa uccuccucac caucgacaga uaucucgcca      480

uaguccacgc cgucuuugca cuccgcgccc gcaccgucac cuucgguguc aucaccucca      540

ucauaaucug ggccuuagcc auccucgccu ccaugcccgg acucuacuuu uccaaaaccc      600

aaugggaguu cacccaccau accugcuccc uccacuuccc ccacgaaucc cuacgcgaau      660

ggaaacucuu ccaagcacua aaacuaaacc ucuuuggccu cguccuuccc cuccuaguca      720

ugaucaucug cuacacaggc aucaucaaaa uccuacuucg ucgcccuaau gaaaagaaau      780

ccaaagccgu ccgacucauc uucgucauca ugauaaucuu uuuccucuuc uggacacccu      840

auaaucucac cauccucauc ucugucuucc aagacuuccu cuucacacac gaaugcgaac      900

aaucccgcca ccuagaccuc gccguccaag ucaccgaagu caucgcauac acccacugcu      960

gcgucaaccc cgucauauac gcauucgucg gcgaacgcuu ccgcaaguac cuccgccaac     1020

ucuuccaccg acgcgucgca guccaucucg ucaaaugguu acccuuucuc ucugucgacc     1080

gccucgaacg cguauccuca acaucacccu ccaccggcga acaugaacuu ucagccggcu     1140

ucuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  7133
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt9)

<400>  7133
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgaacccucg ccugccuccu ccuccucggc ugcggcuacc      120

ucgcccacgu acucgccgaa gaagcagaaa ucccccgcga agucaucgaa cgccucgcac      180

gcucccaaau ccacuccauc cgugaccucc aacgacuccu ggaaaucgac uccgucggau      240

ccgaagacuc ccuagacacc ucccuaagag cccacggcgu acacgccaca aaacacgucc      300

ccgaaaaacg accccucccc auccgcagaa aacgauccau agaagaagcc guccccgccg      360

uaugcaaaac acgcacaguc aucuacgaaa uaccccgcuc ccaagucgac ccaaccuccg      420

ccaacuuccu aaucuggccc cccugcgucg aagucaaacg cugcaccggc ugcugcaaca      480

ccuccucagu caaaugccaa cccagccgcg uccaccaccg cagcgucaaa gucgcaaaag      540

ucgaauacgu acgcaaaaaa cccaaacuca aagaagucca agucagacuc gaagaacacc      600

uagaaugcgc augcgccacc accagccuaa acccagacua ccgcgaagaa gacaccggcc      660

gaccccgcga auccggcaaa aaacgcaaac gcaaaagacu aaaacccacc uaaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  7134
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt9)

<400>  7134
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaccgcugcu gggcccuauu ccuaagccua ugcugcuacc      120

uccgccuagu cucggccgag ggcgacccca uccccgaaga acucuacgaa augcucagcg      180

aucacucaau ccgcuccuuc gacgaccucc aacgccuccu ccacggcgac cccggcgaag      240

aagacggagc cgaacuagac cucaacauga cacgcucaca cuccggaggg gaacucgaau      300

cccucgcacg cggccgccgc agccuaggcu cacuaacaau cgccgaacca gcaaugaucg      360

ccgaaugcaa aacaagaaca gaagucuucg aaaucucacg ccgccuaauc gaccgcacca      420

acgccaacuu ccuagucugg ccacccugcg ucgaagucca aagaugcucc ggaugcugca      480

acaacagaaa cguccaaugc cgccccaccc aaguccaacu ccgaccagua caaguaagaa      540

aaauagaaau cguccgcaaa aaacccaucu ucaaaaaagc aaccguaacc cucgaagacc      600

accucgcaug caaaugcgaa accgucgccg cagcccgccc cgucacccgc agccccggcg      660

gaagccaaga acaacgagca aaaacacccc aaaccagagu caccauccga acaguccgcg      720

uacgcagacc ccccaaagga aaacaccgca aauucaaaca cacacacgac aaaaccgccc      780

uaaaagaaac ccuaggcgcc uaaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  7135
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt9)

<400>  7135
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucccucuucg gccuacuccu ccuaacaucu gcacucgccg      120

gccaacgcca aggcacccaa gccgaaucca accucagcuc uaaauuccaa uucuccucaa      180

acaaagaaca aaacggcguc caagaccccc aacacgaacg cauaaucaca gucucaacca      240

acggcuccau ccauucaccc cguuuccccc acaccuaccc ccgcaacacc guccuaguau      300

ggcgccuagu agcaguagag gaaaacgucu ggauccaacu caccuucgac gaacgcuuug      360

gacucgaaga uccagaagac gauaucugca aauacgacuu cgucgaagua gaagaaccuu      420

ccgacggcac aauccuaggc cgauggugcg gcuccggcac cgucccaggc aaacaaauau      480

ccaaaggcaa ccaaauccgc auccgcuucg ucuccgacga auacuucccc uccgaacccg      540

gcuucugcau ccacuacaac aucgucaugc cccaauucac cgaagccguc ucccccuccg      600

uccucccacc cuccgcacuc ccccuagacc ugcucaacaa cgccaucacc gccuucucaa      660

cccucgagga ccucauacgc uaccuagagc ccgaacgcug gcaacucgac cucgaagacc      720

ucuaccgccc aacauggcaa cuccucggca aagccuucgu cuucggccgc aaaucccgcg      780

uagucgaccu aaaccuacua accgaagaag uacgccucua cagcugcaca ccacgcaacu      840

ucucagucuc cauccgcgaa gaacucaaac gcaccgacac caucuucugg ccaggcugcc      900

uccuaguaaa acgcugcggc gggaacugcg ccugcugccu ccacaacugc aacgaaugcc      960

aaugcguccc auccaaaguc accaagaaau accacgaagu gcuacaacua agaccaaaaa     1020

ccggcguccg cggacuccac aaaucucuca ccgacguagc ccuagaacac cacgaagaau     1080

gcgacugcgu cugccgcggc uccaccggcg gcuaaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  7136
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt9)

<400>  7136
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgccuca uauuugucua cacacugaua ugcgccaacu      120

ucuguucaug ccgcgacacc uccgccaccc cccaaucugc cuccauaaaa gcccucagaa      180

acgccaaccu acgacgcgac gaccucuacc gacgcgacga aacaauacaa gucaaaggca      240

acggcuacgu acaaucccca cgcuucccca acuccuaccc ccgcaaccuc cuccucaccu      300

ggcggcuaca cucccaagaa aacacccgca uacagcuugu auucgacaac caauucggcc      360

uagaagaagc cgagaacgac aucugccgau acgacuucgu cgaagucgaa gacaucagcg      420

aaaccuccac caucaucaga ggaagauggu gcggccacaa agaagucccc ccucgaauca      480

aaucccgcac aaaccagaua aaaauaacau ucaaauccga cgacuacuuc gucgccaaac      540

ccggcuucaa aaucuacuac ucccuccucg aagauuucca acccgccgcc gccuccgaaa      600

caaacuggga auccgucacc uccuccauau ccggugucuc auacaacucc ccaagcguca      660

cagacccaac ccucauugca gacgcacuag acaaaaaaau cgccgaauuc gacaccgucg      720

aggaccuccu aaaauacuuc aaccccgaau ccuggcaaga agaccucgaa aacauguacc      780

ucgacacacc ccgcuacaga ggccgcuccu accacgaccg caaauccaag gucgaccucg      840

accgccucaa cgacgacgcc aaacgcuaca gcugcacacc ccgcaauuac agugucaaca      900

ucagagagga acuaaaacua gccaacguag ucuucuuccc acgcugccua cuaguacagc      960

gaugcggcgg caacugcggc ugcggcaccg ugaacuggcg guccugcacc uguaacuccg     1020

gcaaaacagu aaaaaaauau cacgaagucc uacaguuuga acccggacac aucaaacgcc     1080

guggccgcgc caaaacuaug gcccucguug acauccaacu cgaccaccac gaacgcugcg     1140

acugcauaug cucuucccgc ccaccccgau aaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  7137
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt9)

<400>  7137
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccauu caaaauuccc cgccgccggc augucccgcc      120

cccucgacac cucccuccgc cucaaaacau ucuccuccaa auccgaauac caacucgucg      180

ucaacgccgu ccgcaaacuc caagaauccg gcuucuacug gucugccguc accggaggcg      240

aagccaaccu ccuacuauca gccgaaccag cuggcaccuu ccuaauccgu gacuccuccg      300

accaacgcca cuucuucacc cucucaguca aaacccaauc cggcaccaaa aaccuccgca      360

uccaaugcga aggcggaucc uucucccuac aauccgaccc ccgcucaacu caaccagucc      420

cccgauucga cugcguccuc aaacucgucc accacuacau gcccccaccc ggagcccccu      480

ccuuccccuc cccacccacc gaacccuccu ccgaaguccc cgaacaaccc uccgcccaac      540

cccuccccgg aucaccaccc cgccgcgccu acuacaucua cuccggcggc gagaaaaucc      600

cccuaguccu cucccgccca cucucaucca auguugccac ccuacaacac cucugccgua      660

aaaccguaaa cggacaccua gacuccuacg aaaaaguuac ccaacuaccc ggccccaucc      720

gcgaauuucu cgaccaauac gaugcacccc ucuaaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  7138
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt9)

<400>  7138
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guccccuccg ccggccaacu agcccucuuc gcccuaggca      120

ucguccucgc agccugucaa gcacucgaaa acuccaccuc cccccucuca gccgacccac      180

ccguagccgc agccguaguc ucccacuuca acgacugccc cgacucccac acccaauucu      240

gcuuccacgg aaccugccga uuccucgucc aagaagacaa acccgccugc guaugccacu      300

ccggcuacgu cggcgcccgc ugcgaacacg ccgaccuccu agccguagua gccgccucac      360

aaaaaaaaca agccauaacc gcacucguag ucgucuccau cgucgcccuc gccguccuua      420

uaauaaccug cguccucauc cacugcugcc aaguacgcaa acacugcgaa uggugccgcg      480

cccucaucug cagacacgaa aaacccuccg cacuacucaa aggccgcacc gccugcugcc      540

auuccgaaac cguaguauaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  7139
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt9)

<400>  7139
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaccauccg gccuacgucu ccucccucuc cuccugccac      120

uccucuggcu auuaguccua acaccaggcc gcccagccgc cggccucuca accugcaaaa      180

cuaucgacau ggaacuuguc aaacgcaaac gaauagaagc cauccgcggc caaauccuau      240

ccaaacuccg ccucgccucc ccacccucac aaggcgaagu accacccgga ccccuacccg      300

aagccguccu ugcacucuau aacuccaccc gcgaccgagu ugcuggagaa ucagccgaac      360

ccgaaccaga gccagaagcc gacuacuacg ccaaagaagu cacccgcgua cucauggucg      420

aaacacacaa cgagauauac gauaaauuca agcaauccac ccacuccaua uacauguucu      480

ucaacaccuc agaacuacga gaagccgucc ccgaacccgu ccuacuauca cgagccgaac      540

uucgucuccu ccgacucaaa cucaaggucg aacaacacgu cgaacucuac caaaaauauu      600

caaacaacuc auggcgcuac cuaucaaacc gccuacuagc accaucagac ucacccgaau      660

ggcuaucauu cgacgucacc ggagucgucc gccaauggcu aucacgagga ggcgaaaucg      720

aaggcuucag acucucagcc cacugcuccu gcgacucccg agacaacacc cuccaagucg      780

acaucaacgg cuucaccacc ggccgacgcg gagaccucgc cacaauacac ggaaugaacc      840

gacccuuccu acuccucaug gcaacaccac ucgaacgcgc ccaacaccuc caaucuuccc      900

gccaccgccg agcccuggac accaacuacu gcuucuccuc cacugagaaa aauugcugcg      960

ugagacaacu cuacaucgac uuccgcaaag accucggcug gaaauggauc cacgaaccaa     1020

aaggcuacca cgcaaacuuc ugccucggcc ccugcccaua cauauggucc cuagacaccc     1080

aauacuccaa aguucuagcc cuauacaacc aacacaaccc cggcgccucc gcggcucccu     1140

gcugcguucc ccaagcccuc gaaccccucc caauagucua cuacgucggc cgcaaaccaa     1200

aagucgaaca acucuccaac augaucgucc gauccugcaa augcuccuaa ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  7140
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt9)

<400>  7140
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uacucucagc cuuccucauc cuccaccucg      120

ucaccgucgc acuaucacua ucuaccugca gcacacucga uauggaccaa uucaugcgca      180

aacgcauaga agcuauccgu ggccaaaucc uauccaaacu caagcucacc agcccacccg      240

aagacuaucc ugaacccgaa gaagucccac ccgaaguaau cuccaucuac aacuccacac      300

gcgaccuccu acaagaaaaa gccucccgac gcgcagccgc cugcgaacga gagcgcuccg      360

acgaagaaua cuacgccaaa gaaguauaca agauagacau gccacccuuc uucccuuccg      420

aaaacgccau acccccaacc uucuaccgcc cauacuuccg caucguccgc uucgacgucu      480

cugcuaugga gaaaaaugca uccaaccucg ucaaagccga guuccgcgua uuccgccuac      540

aaaaccccaa agcgcgcguc ccugaacaac gcaucgaacu cuaccagauc cucaaaucca      600

aagaucuuac cucgcccaca caacgcuaca ucgacuccaa agucguaaag acccgcgccg      660

aaggagaaug gcucuccuuc gacguaaccg acgccgucca cgaauggcua caccacaaag      720

accgcaaccu cggcuucaaa aucucccuac acugccccug cugcaccuuc guccccucca      780

acaauuacau cauccccaau aaauccgaag aacucgaagc cagauucgcc ggcaucgacg      840

gcaccucaac cuacacaucc ggcgaccaga aaaccaucaa aucaacccgc aagaaaaacu      900

ccggcaaaac cccacaucuc cuccucaugc uucucccuuc auaccgucuc gaaucucaac      960

aaaccaaccg acgcaagaaa cgcgcccucg acgccgccua cuguuuccgc aacguccaag     1020

acaacugcug ccuacgaccc cucuacauag acuucaaacg cgaccucggc uggaaaugga     1080

uccacgaacc caaaggcuac aacgcuaacu ucugcgcggg cgccugcccc uaccuauggu     1140

ccuccgacac ccaacacuca cgcguccucu cccucuacaa caccaucaau ccugaagccu     1200

ccgccucacc cugcugcguc ucccaagacc ucgaaccacu caccauacua uacuacaucg     1260

gcaaaacgcc uaaaauagaa caacuaucua acaugaucgu caaauccugu aaaugcagcu     1320

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  7141
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt9)

<400>  7141
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaugcacc uccaacgcgc ccuagucgua cucgcacuac      120

ucaacuuugc caccguauca cuuucacucu ccacaugcac cacacucgac uuuggccaca      180

ucaaaaagaa acgagucgaa gcuauacgag gccaaauccu aucaaaacua cgccucacau      240

ccccacccga acccacagua augacccacg uccccuacca aguacucgcc cuauacaacu      300

ccacccgcga acuccuagaa gaaaugcacg gagaaagaga agaaggaugc acccaggaaa      360

acaccgaauc agaauacuac gccaaagaaa uacacaaauu cgacaugauc caaggccucg      420

ccgaacacaa cgaauuagcc gucugcccca aagguaucac uagcaaagua uuccgauuca      480

acguuuccuc ggucgagaaa aaccgcacca accuauuccg agccgaguuc cguguccucc      540

gcguccccaa cccaagcuca aaacgcaacg aacaacgcau cgaacuuuuc caaauacuaa      600

gacccgacga acacaucgcc aaacaacgcu acauaggcgg caaaaaccuc ccaacccgcg      660

gcaccgcaga auggcucucu uucgacguca ccgacaccgu acgugaaugg cuacucagac      720

gcgaauccaa ccuaggucua gaaaucucaa uacacugccc cugccacacc uuccaaccaa      780

acggagacau ccucgaaaac auccacgaag ucauggaaau caaauucaaa ggagucgaca      840

augaagacga ccacggacga ggcgaccucg gacgacucaa aaagcaaaaa gaccaccaca      900

acccccaccu cauccuaaug augaucccac cccaccgccu cgacaacccc ggacaaggcg      960

gccaacgcaa gaaacgcgcc cucgacacca acuacugcuu ccgcaaccua gaagaaaacu     1020

gcugcguacg cccccucuac aucgacuucc gacaagaccu aggcuggaaa uggguccacg     1080

aacccaaagg auacuacgca aauuucugca gcggaccaug cccauaccua cgguccgccg     1140

acacaaccca cuccacaguc cuaggacuuu auaacacccu aaacccagaa gccuccgccu     1200

cccccugcug ugucccccaa gaccuugaac cucucaccau ccuuuacuac gucggcagaa     1260

cccccaaagu cgaacaacua uccaacaugg ucgucaaauc cugcaaaugc uccuaaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  7142
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt9)

<400>  7142
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacccguug cagucugggc agcccuugcc gucggccucg      120

aacucugggc cgcugcccac gcccuccccg cccaaguugc cuucacuccu uacgccccag      180

aaccaggcuc cacaugccga cuccgagaau acuaugacca aacagcccaa augugcugcu      240

ccaagugcuc ccccggccaa cacgccaaag ucuucuguac caaaaccucu gacaccgucu      300

gcgacuccug cgaagacucc acuuacaccc aacuauggaa cuggguaccc gaaugccucu      360

ccugcggcuc cagaugcuca uccgaccaag ucgaaaccca agcaugcaca cgcgaacaaa      420

accgaaucug cacaugcagg cccggauggu acugcgcacu cuccaaacaa gaaggcugcc      480

gccucugcgc accccuccga aaaugccgac caggcuucgg cgucgcccgc ccaggaacag      540

aaaccuccga cguagucugc aaacccugcg ccccuggcac uuucuccaac acaaccagcu      600

caaccgacau augccgccca caccaaaucu gcaacgucgu ugcaauaccc ggcaacgcau      660

ccauggacgc cgucugcacc uccacaucgc ccacccgauc cauggcaccc ggcgccgucc      720

accuccccca accugucuca acccgaucac aacacacaca acccaccccc gaacccucaa      780

ccgccccauc caccucauuc cuucuaccca ugggccccuc cccacccgcc gaaggcucca      840

ccggagacuu cgcccuccca gucggccuaa ucgucggcgu caccgcccua ggccugcuca      900

ucaucggagu cgucaacugc guaaucauga cccaagucaa aaagaagccc cuaugucucc      960

aaagagaagc aaaaguaccu caccuccccg ccgacaaagc ccgcggcaca caaggccccg     1020

aacaacaaca ccuccuaauc accgccccau cauccuccuc aucaagccuc gaaucaucag     1080

caucagcucu cgaccgccgc gccccaacca gaaaccaacc ccaggcccca ggcguagaag     1140

ccuccggagc cggagaagcc cgagccucaa caggcuccuc cgacagcucu cccggcggcc     1200

acggcacaca aguaaacgua accugcaucg ucaauguaug cucgucaucc gaccauuccu     1260

cccaaugcuc aagccaagcc ucaucaacca ugggcgacac cgacucaagc ccaucugaau     1320

cccccaaaga cgaacaagua cccuucagua aagaagaaug ugccuuccga ucccaauuag     1380

aaacccccga aacacuccua ggauccaccg aagaaaaacc cuuaccccuc ggugucccag     1440

acgccggcau gaaacccucc uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  7143
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt9)

<400>  7143
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggucaugc gcuuguuccc gugcuuucua cagcucuugg      120

cagggcucgc acucccagcc gugcccccgc aacagugggc guuaucggcc gggaacggga      180

gcucggaagu ggaaguggua ccguuccagg aagugugggg gcgcucguac ugucgcgcgc      240

uagagcgccu ggucgauguc gugagugagu acccgagcga ggucgagcac auguucucgc      300

ccucaugcgu gagcuugcuc aggugcacgg gcuguugcgg ggacgagaac cugcacugug      360

ucccggucga gaccgcgaac gugaccaugc aauugcucaa gaucaggagc ggggacaggc      420

ccucguacgu ggaauugacc uucagccagc acguacgcug ugaaugucgc ccacucaggg      480

aaaagaugaa gccagaacgc aggcgaccga aagggcgcgg gaaaaggcgc agagaaaagc      540

aaaggcccac agacugucac uuaugcgggg acgcgguccc gaggcgcuga ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  7144
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt9)

<400>  7144
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagaccgcc agacagacac cgcgccaucg cccucguacc      120

accuccugcc cgggagaagg cgcacggucg acgccgcagc cucgcgagga caagggcccg      180

agccagcgcc aggaggcggg guagagggcg ugggagcgcg aggggucgcg cucaaacucu      240

ucguccagcu ucugggcugc agcagguucg ggggcgcagu agugcgcgca ggcgaagccg      300

agcccucagg cgcggccagg agcgcaagcu caggcagaga ggaaccccag cccgaggagg      360

gggaagaaga agaggaaaaa gaagaagaaa gggguccaca auggcgccug ggcgcgcgca      420

agccaggaag uuggaccgga gaagcagcag ugugcgcgga cucugcacca gccgcgcgag      480

cgccccaggc auuggccaga gcaucaggca gaggaggacg aguggcaaga agaggagccg      540

aggaaucagg accgccccau agcccaagca ggcgagggag ugcgagcaga gccggaccag      600

ggcgcgcaag cgagacaaug aacuuccucc ugagcugggu acacuggucg cuagcacugu      660

ugcucuaccu ccaucacgca aaauggagcc aggccgcgcc aauggccgag ggaggaggac      720

aaaaccacca cgagguagug aaauucaugg acgucuacca aaggagcuau ugccacccca      780

uagaaacgcu aguggacaua uuccaggaau auccagacga aauagaguac auauucaaac      840

caagcugcgu gccgcucaug aggugcggcg gaugcuguaa cgaugaaggg cuagagugcg      900

uacccacgga agagagcaac aucaccaugc agaucaugag gauaaaaccg caccagggcc      960

agcacauagg agagauguca uuccugcaac acaacaagug cgagugccgg cccaagaaag     1020

accgagcaag acaggaaaag aaaucaguaa ggggaaaggg caagggacag aaaagaaaaa     1080

gaaagaagag uagguacaag agcuggagug uauacguagg ggcgagaugc ugccugaugc     1140

cauggagccu accgggaccg cacccaugcg gacccugcag cgaacgcagg aaacaccugu     1200

ucguccagga cccacaaaca ugcaaguguu caugcaagaa cacagacucg cgcuguaaag     1260

cacgccaacu cgagcuuaac gaaaggacau gccgcugcga caaacccagg agauaaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  7145
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt9)

<400>  7145
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuac ucagcugggu ccacugguca cucgcccucc      120

uccucuaccu ccaccacgcc aaaugguccc aagccgcccc cauggccgaa ggcggcggcc      180

aaaaccacca cgaaguagua aaauucaugg acguauacca acgcagcuac ugccacccca      240

ucgaaacccu aguagacauc uuccaagaau accccgacga aaucgaauac auauucaaac      300

ccuccugcgu cccacucaug cgcugcggcg gcugcugcaa cgacgaaggc cucgaaugcg      360

uccccacaga agaaagcaac aucacaaugc agauaaugcg aaucaaaccc caccaaggcc      420

agcacaucgg cgaaauguca uuccuccaac acaacaaaug cgaaugccga ccaaaaaaag      480

accgcgcaag acaagaaaaa aaauccguca gaggcaaagg caaaggccaa aaacgaaaac      540

gcaaaaaauc ccgcuacaaa agcuggucag ucuacguagg cgcccgcugc ugccucaugc      600

cauggucccu ccccggcccc caccccugcg ggcccugcag cgaacgccgc aaacaccucu      660

ucguccaaga cccacaaacc ugcaaaugcu ccugcaaaaa caccgacucc cgcugcaaag      720

cccgccaacu cgaacuaaac gaacgcaccu gccgcugcga caaaccccga agauaaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  7146
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt9)

<400>  7146
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccccccucc uccgccgacu ccuacuagcc gcccuccuac      120

aacucgcccc cgcacaagcc cccgucuccc aacccgacgc ccccggccac caacgcaaag      180

ucguauccug gauagacgua uacacccgcg ccaccugcca accacgagaa gucguagucc      240

cacucacagu cgaacucaug ggcaccgucg caaaacaacu cguaccauca ugcguaaccg      300

uccaacgaug cggcggcugc ugccccgacg acggccuaga augcgucccc accggccaac      360

accaagucag aaugcaaauc cucaugaucc gcuaccccuc cucccaacuc ggcgaaaugu      420

cacucgaaga acacucccaa ugcgaaugcc gccccaaaaa aaaagacuca gccguaaaac      480

ccgaccgcgc cgccacacca caccaccgac cccaaccccg cucaguccca ggcugggacu      540

ccgcccccgg cgcacccucc cccgccgaca ucacccaccc cacccccgca cccggccccu      600

ccgcacacgc cgccccaucc accaccuccg cccucacccc cggccccgcc gccgccgccg      660

ccgacgccgc cgccagcucc gucgcaaaag gcggcgccua aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  7147
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt9)

<400>  7147
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuccucg gauucuucuc cgucgccugc ucccuacucg      120

ccgccgcacu ccuccccggc ccacgcgaag caccagcagc cgccgccgca uucgaaucag      180

gccucgaccu auccgacgcc gaaccagacg ccggcgaagc caccgccuau gcaagcaaag      240

accucgaaga acaacuacga uccguaucau ccguggacga acuaaugacc guccucuacc      300

cagaauacug gaaaauguac aaaugccaac uccgaaaagg cggauggcaa cauaaccgcg      360

aacaagccaa ccucaacagc cgaaccgaag aaacaaucaa auucgccgcc gcccacuaca      420

acacggaaau acuaaaaucc aucgacaacg aauggagaaa aacacaaugc augccccgug      480

aagucugcau cgacgucggc aaagaauuug gcgucgccac caacacauuc uucaaaccac      540

ccugcgucuc aguauaccga ugcggcgggu gcugcaacuc cgaaggccua caaugcauga      600

acaccuccac cucauaccuc ucaaaaaccc ucuucgaaau aacaguucca cucagccaag      660

gccccaaacc cgucacgaua uccuucgcaa accauacuuc augccgcugc augucaaaac      720

uugacguaua ccgccaaguc cacuccauca uccgaagauc acuacccgcc acccuacccc      780

aaugucaagc cgccaacaaa accugcccca ccaacuacau guggaacaac cacauuugcc      840

gcugccuagc ccaagaagac uucauguucu caucggacgc cggcgacgac ucaaccgacg      900

gcuuccacga cauaugcggc cccaacaaag aacuagacga agaaacaugc caaugcgucu      960

gccgcgccgg ccuccgaccc gcauccugcg gaccccacaa agaacuggac cgcaacucau     1020

gccaaugcgu cugcaaaaac aaacucuucc ccucccaaug cggcgcaaac cgcgaguucg     1080

acgaaaauac cugccaaugc gucugcaagc gaaccugccc acgcaaccaa ccccucaacc     1140

ccggaaagug cgccugcgaa ugcaccgaaa gcccacaaaa augccuucuc aaaggaaaga     1200

aauuccacca ccaaaccugc ucaugcuacc gccgccccug caccaaccgc caaaaagccu     1260

gcgaacccgg cuucucauac uccgaagaag uaugccgcug cguuccaagc uacuggaaac     1320

gcccccaaau guccuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  7148
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt9)

<400>  7148
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uaccgagaau ggguagucgu caacgucuuc augaugcucu      120

acguccaacu gguccaaggu ucauccaacg aacauggccc cgucaaacgc uccucccaga      180

gcacccucga gcgcuccgaa caacaaaucc gcgcugccuc cucucuagaa gaacuucucc      240

gaaucaccca cucugaagac uggaaauuau ggcgaugccg ccuacgucuc aagagcuuca      300

ccucaaugga cucccgaucc gcaucccacc gcucuacacg auucgccgcc accuucuacg      360

acaucgaaac ccucaaaguc auagacgaag aauggcaacg cacccaaugc uccccaaggg      420

aaaccugcgu cgaaguagcc uccgaacucg gcaaauccac caacacauuc uucaaaccuc      480

ccugcgucaa cgucuuccgc ugcggcggcu gcugcaacga agaaucccuc aucugcauga      540

acacauccac cuccuacaua uccaaacaac uauucgaaau uucugucccc cucaccucgg      600

uccccgaacu cguccccguc aaaguagcca accacaccgg cugcaaaugc cugcccaccg      660

ccccacgaca ccccuauucc aucauccgac gcuccauaca gauucccgaa gaagaccgau      720

gcucccacuc aaagaaacuc ugccccauag acaugcuaug ggacucaaac aaaugcaaau      780

gcguccucca agaagaaaac ccacucgccg gcacugaaga ccacucgcac cuccaagaac      840

ccgcccucug cggaccccac augauguucg acgaagaccg cugcgaaugc gucugcaaaa      900

ccccaugccc caaagaccuc auccaacacc ccaaaaacug cucaugcuuc gaaugcaaag      960

aaucccucga gaccugcugc caaaaacaca aacucuucca ccccgauacc ugcuccugcg     1020

aagaccgcug ccccuuccac acacgcccau gcgccuccgg caaaaccgca ugcgcaaaac     1080

acugccguuu cccaaaagaa aaacgcgccg cccaaggccc ccacucccgc aaaaaccccu     1140

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  7149
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt11)

<400>  7149
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacuccgacg aaaccggcuu cgaacacuca ggccucuggg      120

ucuccguacu agccggccuc cuccucggcg ccugccaagc ccaccccauc cccgacuccu      180

caccccuccu acaauucggc ggccaagucc gccaacgcua ccuauacacc gacgacgccc      240

aacaaaccga agcccaccuc gaaauccgcg aagacggcac cgucggcggc gccgccgacc      300

aaucccccga aucccuacua caacucaaag cccucaaacc uggagucauc caaauacucg      360

gcgucaaaac cucccgcuuc cucugccaac gccccgacgg agcccucuac ggcucccucc      420

acuucgaccc agaagccugc ucuuuccgag aacuccucuu agaagacggc uacaacgucu      480

accaaucuga agcccacggc cucccccuuc accuccccgg aaacaaauca ccccaccgcg      540

accccgcacc ccgcggccca gccagauucc ucccccuccc cggccuccca ccagcccucc      600

ccgaaccacc cggcauccuc gcaccccaac cacccgacgu cggcuccucc gacccccucu      660

caauggucgg ccccucccaa ggccgcuccc ccucauacgc cucauaagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  7150
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt11)

<400>  7150
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagcuucc caccccuccu ccuccuccug uucuggggcg      120

ucgucucaca cuccuuuccc gcuacccucg aaacccaaga acaagacguc gaccucguac      180

aaaaguaccu cgaaaaauac uacaaccuua aaaacgacgg ccgucaaguc gaaaagcgcc      240

gcaacucagg ccccgucguu gaaaaacuca aacaaaugca agaauuuuuc ggccugaaag      300

ucacaggaaa acccgacgcc gaaacccuca aagucaugaa acaaccccgc ugcggagucc      360

ccgacguagc ccaauucguc cuaaccgaag gcaacccccg cugggaacaa acccaccuca      420

cauaccgcau cgaaaacuac acccccgacc uuccccgcgc cgacgucgac cacgccauag      480

aaaaagcauu ccaauuaugg uccaacguca ccccacucac cuucacuaag gucuccgaag      540

gccaagcaga cauaaugauc ucuuucgucc gcggcgacca ccgagacaac ucccccuucg      600

acggccccgg aggcaaccug gcccacgcau uccaaccagg ccccggcauc ggaggagacg      660

cccacuucga cgaagacgaa cgcuggacaa acaauuucag agaauacaac uuacaucgcg      720

ucgccgccca cgaacucggc cacagccucg gccucucaca cuccacagau aucggcgccc      780

uaauguaccc cuccuacacc uucuccggcg acguccaacu agcccaagac gacauagacg      840

gcauccaagc cauauacggc cgaucccaaa accccguaca gcccaucgga ccacaaacuc      900

ccaaagccug cgacuccaaa cucaccuucg acgccaucac cacaauacga ggcgaaguga      960

uguucuucaa agacagauuc uauaugagaa ccaacccguu cuaccccgaa gucgaacuua     1020

acuucaucuc agucuucugg ccacaacuac caaacggccu cgaagcagcc uacgaauuug     1080

ccgaccgcga cgaaguccga uucuucaagg gcaacaaaua cugggccguc caaggccaaa     1140

acguccugca cggcuaccca aaagacaucu auuccagcuu cggcuuccca cgcacuguca     1200

aacauaucga ugccgcccuc agcgaagaaa acacaggcaa aacauacuuc uucgucgcua     1260

acaaauacug gcgcuacgau gaauacaaac gcuccaugga cccaggcuau ccuaaaauga     1320

ucgcccacga cuuccccggc aucggccaca aggucgaugc cgucuucaug aaggacggau     1380

ucuucuacuu cuuccacgga acccgccaau acaaguucga ccccaaaacu aagcgaaucc     1440

ucacccucca aaaagccaac uccugguuca acugccgcaa aaacuaagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  7151
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt11)

<400>  7151
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauucauucc caccacuacu acuccuccua uucuggggag      120

ucgucuccca uuccuucguc cucacagaag gcaacccccg cugggaacaa acccaccuca      180

ccuaccgcau agaaaacuac accccagacc ucccccgcgc cgacgucgac cacgccaucg      240

aaaaagcguu ccaacuaugg ucuaacguaa caccccucac cuucaccaaa gucuccgaag      300

gccaagccga cauaaugauc ucauucguca gaggcgacca ccgcgacaac ucucccuucg      360

acggccccgg aggcaaccuc gcacacgccu uccaacccgg ccccggaauc ggcggcgacg      420

cccacuucga cgaagacgaa cgcuggacca acaacuuccg agaauacaac cuccaccgcg      480

ucgccgcaca cgaacucggc cacagccucg ggcucucaca cuccaccgac aucggugccc      540

ucauguaccc cucauacaca uucucuggcg acguccaacu cgcacaagac gacaucgacg      600

gcauccaagc caucuacggc cgaucccaaa acccagucca acccauaggc ccacagacac      660

ccaaagcaug cgacuccaaa cucaccuucg acgccauaac caccauccgc ggcgaaguaa      720

uguucuucaa agacagauuc uacaugcgca ccaaccccuu cuacccagaa guugaauuaa      780

acuucaucuc cgucuucugg ccacagcucc caaacggucu cgaagccgca uacgaauuug      840

cagaccgaga cgaaguacga uucuucaaag gcaacaaaua uugggccgua caggggcaaa      900

auguccucca cggcuacccu aaagacaucu acuccuccuu cggcuucccc cgcacaguca      960

aacacaucga cgccgcccuc uccgaagaaa acaccggcaa aaccuacuuc uucgucgcca     1020

acaaauacug gcgauacgac gaauacaaac gcuccaugga ccccggauac cccaaaauga     1080

ucgcccacga cuuccccggc aucggccaca aaguagacgc cguuuucaug aaagacggau     1140

ucuucuacuu cuuccacgga acaagacagu acaaauucga cccaaagacc aaacggaucc     1200

ucacccucca aaaagcaaac uccugguuca auugccgcaa aaauuaagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  7152
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt11)

<400>  7152
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaagaaca uccugaagau ccucauggac agcuacucca      120

aggagagcaa gauccagacc gugcgccggg ucaccuccgu gagccugcug gccguguacc      180

ucacgaugaa caccuccagc cugguccugg ccaagcccau cgagaacacc aacgacaccu      240

ccaucaagaa cguggagaag cuccgcaacg cgccgaacga ggagaacagc aagaaggugg      300

aggacuccaa gaacgacaag gucgagcacg ugaagaacau cgaggaggcc aagguggagc      360

aggucgcccc cgaggucaag agcaagucca cgcugcggag cgccuccauc gccaacacca      420

acagcgagaa guacgacuuc gaguaccuga acggccucuc cuacaccgag cugaccaacc      480

ugaucaagaa caucaagugg aaccagauca acggccucuu caacuacagc acgggguccc      540

agaaguucuu cggggacaag aaccgcgugc aggcgaucau caacgcccug caggagagcg      600

gccggaccua caccgccaac gacaugaagg ggaucgagac cuucacggag gugcugcgcg      660

ccggcuucua ccucggcuac uacaacgacg ggcuguccua ccugaacgac cggaacuucc      720

aggacaagug cauccccgcg augaucgcca uccagaagaa ccccaacuuc aagcucggca      780

ccgccgugca ggacgaggug aucaccagcc uggggaagcu gaucggcaac gccagcgcca      840

acgcggaggu cgugaacaac ugcgugccgg uccucaagca guuccgcgag aaccugaacc      900

aguacgcccc cgacuacgug aaggggaccg ccgugaacga gcugaucaag ggcaucgagu      960

ucgacuucuc cggcgccgcc uacgagaagg acgucaagac gaugcccugg uacgggaaga     1020

ucgaccccuu caucaacgag cucaaggcgc ugggccugua cgggaacauc accagcgcca     1080

ccgagugggc cuccgacgug ggcaucuacu accucagcaa guucggccug uacuccacca     1140

accggaacga caucgugcag agccuggaga aggccgucga cauguacaag uacgggaaga     1200

ucgccuucgu ggcgauggag cgcaucacgu gggacuacga cggcaucggg uccaacggca     1260

agaaggucga ccacgacaag uuccucgacg acgccgagaa gcacuaccug ccgaagaccu     1320

acaccuucga caacgggacc uucaucaucc gggccggcga caaggugagc gaggagaaga     1380

ucaagcgccu guacugggcc ucccgggagg ucaagagcca guuccaccgc guggugggca     1440

acgacaaggc ccucgaggug gggaacgcgg acgacguccu gacgaugaag aucuucaacu     1500

cccccgagga guacaaguuc aacaccaaca ucaacggcgu gagcaccgac aacgggggcc     1560

uguacaucga gccccggggg accuucuaca cguacgagcg cacgccccag caguccaucu     1620

ucagccucga ggagcuguuc cggcacgagu acacccacua ccugcaggcc cgcuaccucg     1680

uggacggccu guggggccag gggccguucu acgagaagaa ccggcugacc ugguucgacg     1740

agggcaccgc cgaguucuuc gccgggucca cccgcaccag cggcguccuc ccccggaagu     1800

ccauccuggg guaccuggcg aaggacaagg uggaccaccg cuacagccuc aagaagaccc     1860

ugaacuccgg cuacgacgac agcgacugga uguucuacaa cuacggcuuc gccguggccc     1920

acuaccugua cgagaaggac augcccacgu ucaucaagau gaacaaggcc auccucaaca     1980

ccgacgucaa gagcuacgac gagaucauca agaagcuguc cgacgacgcc aacaagaaca     2040

ccgaguacca gaaccacauc caggagcugg cggacaagua ccagggggcc ggcauccccc     2100

uggugagcga cgacuaccuc aaggaccacg gguacaagaa ggccuccgag guguacagcg     2160

agaucuccaa ggccgccagc cugaccaaca ccuccgucac ggcggagaag ucccaguacu     2220

ucaacaccuu cacccugcgc ggcaccuaca cgggcgagac cagcaagggg gaguucaagg     2280

acugggacga gaugagcaag aagcucgacg gcacccugga gucccuggcc aagaacagcu     2340

gguccgggua caagacccuc acggccuacu ucaccaacua ccgggugacc agcgacaaca     2400

aggugcagua cgacgucgug uuccacggcg ugcugaccga caacgccgac aucuccaaca     2460

acaaggcccc gaucgcgaag gucacggggc ccagcaccgg cgccgugggc cgcaacaucg     2520

aguucuccgg gaaggacagc aaggacgagg acggcaagau cgugagcuac gacugggacu     2580

ucggggacgg cgccaccucc cgggggaaga acagcgucca cgccuacaag aaggcgggca     2640

ccuacaacgu gacgcugaag gugaccgacg acaagggcgc caccgccacc gaguccuuca     2700

cgaucgagau caagaacgag gacaccacca cccccaucac gaaggagaug gagcccaacg     2760

acgacaucaa ggaggccaac gggccgaucg ucgagggcgu gaccgugaag ggggaccuca     2820

acggcagcga cgacgccgac accuucuacu ucgacgucaa ggaggacggg gacgugacca     2880

ucgagcugcc cuacuccggc agcuccaacu ucacguggcu gguguacaag gagggcgacg     2940

accagaacca caucgcgagc gggaucgaca agaacaacuc caaggucggc accuucaaga     3000

gcaccaaggg gcgccacuac guguucaucu acaagcacga cuccgccagc aacaucuccu     3060

acagccucaa caucaagggc cuggggaacg agaagcugaa ggagaaggag aacaacgacu     3120

ccagcgacaa ggccaccgug auccccaacu ucaacacgac caugcagggc ucccuccugg     3180

gcgacgacag ccgggacuac uacuccuucg aggucaagga ggagggggag gugaacaucg     3240

agcuggacaa gaaggacgag uucggcguga ccuggacccu ccaccccgag agcaacauca     3300

acgaccgcau cacguacggg caggucgacg gcaacaaggu gagcaacaag gugaagcugc     3360

ggccgggcaa guacuaccug cucgucuaca aguacuccgg gagcggcaac uacgagcugc     3420

gcgugaacaa gugaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  7153
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt11)

<400>  7153
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga cauucaucag ccuccucuuc uuauucucca      120

gcgccuacuc caucgccaac accaacagcg agaaguacga cuucgaguac cugaacggcc      180

ucucuuacac ggagcugacc aaucugauca agaacaucaa guggaaccag auuaacgggu      240

uauucaacua cagcaccggc ucccagaagu ucuucgggga caaaaaccgc guccaggcga      300

uuaucaacgc ccugcaggag agcggucgga ccuacaccgc uaacgacaug aaggggaucg      360

agaccuucac cgagguucug cgcgccggcu ucuaccucgg cuacuacaac gacgggcugu      420

ccuaccugaa cgaccggaac uuccaggaca agugcauccc cgccaugauc gcgauccaga      480

agaacccgaa cuucaagcuc ggcaccgccg ugcaggacga ggucaucacg agccugggga      540

agcugaucgg caacgccucc gccaacgcgg agguggugaa caacugcguc cccgugcuca      600

agcaauuccg cgaaaaccug aaccaguacg cccccgacua cguaaagggg accgccguca      660

acgagcugau caagggcauc gaguucgacu uuagcggcgc cgccuacgag aaagacguga      720

agaccaugcc cugguacggg aagaucgacc cguucaucaa cgagcucaag gcgcugggcc      780

uguacgggaa caucaccucc gccacggagu gggccagcga cgugggcauc uacuaccucu      840

ccaaguucgg ccuguacucg accaaccgga augacaucgu acagucccug gagaaggccg      900

uggacaugua caaguacggg aagaucgccu ucguggcgau ggagcgcauc accugggacu      960

acgacgguau cgggagcaac ggcaagaagg ucgaccacga caaauuccuc gacgacgccg     1020

agaagcacua ccugcccaag accuacacgu ucgacaacgg caccuucauc auccgggccg     1080

gugacaaggu guccgaggag aagaucaagc gccuguacug ggccagccga gaggucaaga     1140

gccaguucca ccgcguggug ggcaacgaca aggcccucga gguggggaac gcggacgacg     1200

uccugaccau gaagaucuuc aacuccccug aggaguacaa guucaacacc aacaucaacg     1260

gcguguccac ggauaacggg ggccuguaca ucgagccccg ggggaccuuc uacaccuaug     1320

agcgcacccc gcagcagucc aucuucagcc ucgaggagcu guuucggcac gaguacacgc     1380

acuaccugca ggcccgcuac uuaguggacg gccugugggg ccaggggccc uucuacgaga     1440

agaaccggcu gaccugguuc gacgagggca ccgccgaguu cuucgccggu uccacccgca     1500

cgagcggcgu ccucccccga aaguccaucc ugggguaccu ggccaaggac aagguggacc     1560

accgcuacag ccucaagaag acccugaacu ccggcuacga cgacucggac uggauguucu     1620

acaacuacgg cuucgcgguc gcccacuacc uguacgagaa ggacaugccc accuucauca     1680

agaugaacaa ggccauccuc aacaccgacg ugaaguccua cgacgagauc aucaagaagc     1740

ugagcgacga cgccaacaag aacacggagu accagaacca cauccaggag cuggcggaca     1800

aauaccaggg ugccggcauc ccucucgugu ccgacgacua ccugaaggac cacggguaca     1860

agaaggccag cgaggucuac uccgagauua gcaaggccgc cucccugacc aacaccagcg     1920

ugaccgcgga gaagucccag uacuucaaca cguucacccu ccggggcacc uacaccggcg     1980

aaaccagcaa gggggaguuc aaggacuggg acgagaugag caagaagcug gacggcacgc     2040

uggaaucccu ggccaagaac agcugguccg gguacaagac ccucaccgcc uauuuuacca     2100

acuaccgcgu gacgagcgac aacaaggucc aguacgacgu gguguuccac ggcguccuga     2160

ccgacaacgc cgacaucucc aacaacaagg cccccaucgc gaaggugacc gggcccagca     2220

ccggcgccgu gggccggaac aucgaguucu ccgggaagga cucuaaggac gaggacggca     2280

agauagucuc cuacgacugg gacuucgggg acggcgccac gucccgcggg aagaacuccg     2340

uccacgccua caagaaggcc ggcaccuaca acgugacccu gaaggucacc gacgacaaag     2400

gcgcgacggc caccgagagc uucaccaucg agaucaagaa cgaggacacc acgaccccca     2460

ucaccaagga gauggagccg aacgacgaca ucaaggaggc caacgggccc aucguggagg     2520

gcgugaccgu caagggggac cucaacggcu ccgacgacgc agacacguuc uacuucgaug     2580

ugaaggagga cggggacgug accaucgagc ugcccuacag cggcuccagc aacuucaccu     2640

ggcuggucua caaggagggc gacgaccaga accacaucgc guccgggauc gacaagaaca     2700

acagcaaggu gggcaccuuc aagagcacga aggggcgcca cuacguguuc aucuacaagc     2760

acgacuccgc cagcaacauc uccuacagcc ucaacaucaa gggccugggg aacgagaagc     2820

ugaaggagaa ggagaacaac gacuccagcg acaaggccac cgucaucccc aacuucaaca     2880

ccaccaugca gggcucccuc cugggcgacg acagccggga cuacuacucc uucgagguga     2940

aggaggaggg ggaggugaac aucgagcugg acaagaagga cgaguucggc gucacgugga     3000

cccuccaccc ggaauccaac auaaacgacc gcaucaccua cggccaggug gacgggaaca     3060

agguguccaa caaggucaag cugcggcccg gcaaguacua ccugcucgug uacaaguaca     3120

gcggguccgg aaacuacgag cugcgcguga acaagugagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  7154
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt11)

<400>  7154
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccuccucuuc cuguucucca      120

gcgccuacuc caugaagaag aacauccuga agauccucau ggacagcuac uccaaggaga      180

gcaagaucca gaccguccgc cgggugacgu ccgugagccu gcuggccguc uaccucacca      240

ugaacaccuc cagccuggug cuggcgaagc ccaucgagaa caccaacgac acguccauca      300

agaacgugga gaagcuccgc aacgccccga acgaggagaa cagcaagaag gucgaggacu      360

ccaagaacga caagguggag cacgugaaga acaucgagga ggccaagguc gagcaggucg      420

cccccgaggu caagagcaag uccacccugc ggagcgccuc ccgccggcgc cggaagcgca      480

ucgcgaacac caacagcgag aaguacgacu ucgaguaccu gaacggccuc uccuacaccg      540

agcugacgaa ccugaucaag aacaucaagu ggaaccagau caacgggcug uucaacuaca      600

gcaccggcag ccagaaguuc uucggggaca agaaccgggu gcaggccauc aucaacgccc      660

ugcaggaguc cggccgcacc uacaccgcca acgacaugaa ggggaucgag acguucaccg      720

aggugcugcg ggcgggcuuc uaccucggcu acuacaacga cgggcugagc uaccugaacg      780

accgcaacuu ccaggacaag ugcauccccg ccaugaucgc cauccagaag aaccccaacu      840

ucaagcucgg caccgccgug caggacgagg ugaucaccuc ccuggggaag cugaucggca      900

acgccagcgc gaacgccgag guggugaaca acugcguccc ggugcucaag caguuccggg      960

agaaccugaa ccaguacgcc cccgacuacg ugaaggggac ggccgucaac gagcugauca     1020

agggcaucga guucgacuuc uccggcgccg cguacgagaa ggacgugaag accaugcccu     1080

gguacgggaa gaucgacccc uucaucaacg agcucaaggc ccugggccug uacgggaaca     1140

ucaccagcgc caccgagugg gccuccgacg ugggcaucua cuaccucagc aaguucggcc     1200

uguacuccac gaaccgcaac gacaucgucc agagccugga gaaggccgug gacauguaca     1260

aguacgggaa gaucgcguuc gucgccaugg agcggaucac cugggacuac gacggcaucg     1320

gguccaacgg caagaaggug gaccacgaca aguuccucga cgacgccgag aagcacuacc     1380

ugccgaagac cuacaccuuc gacaacggga cguucaucau ccgcgccggc gacaagguga     1440

gcgaggagaa gaucaagcgg cuguacuggg ccucccgcga ggucaagagc caguuccacc     1500

gggugguggg caacgacaag gcgcucgagg ucgggaacgc cgacgacgug cugaccauga     1560

agaucuucaa cucccccgag gaguacaagu ucaacaccaa caucaacggc gugagcaccg     1620

acaacggggg ccuguacauc gagccccgcg ggacguucua caccuacgag cggacgcccc     1680

agcaguccau cuucagccuc gaggagcugu uccgccacga guacacccac uaccugcagg     1740

cccgcuaccu cgucgacggc cuguggggcc aggggccguu cuacgagaag aaccggcuga     1800

ccugguucga cgagggcacc gccgaguucu ucgcgggguc cacccgcacc agcggcgugc     1860

ucccccgcaa gagcauccug ggguaccugg ccaaggacaa gguggaccac cgguacuccc     1920

ucaagaagac gcugaacagc ggcuacgacg acuccgacug gauguucuac aacuacggcu     1980

ucgccgucgc ccacuaccug uacgagaagg acaugcccac cuucaucaag augaacaagg     2040

ccauccugaa caccgacguc aagagcuacg acgagaucau caagaagcuc uccgacgacg     2100

cgaacaagaa caccgaguac cagaaccaca uccaggagcu ggccgacaag uaccaggggg     2160

ccggcauccc ccuggugagc gacgacuacc ucaaggacca cggguacaag aaggccuccg     2220

agguguacag cgagaucucc aaggccgcga gccugaccaa cacguccgug accgccgaga     2280

agucccagua cuucaacacc uucacccugc ggggcacgua caccggcgag accagcaagg     2340

gggaguucaa ggacugggac gagaugagca agaagcucga cggcacccug gagucccugg     2400

ccaagaacag cugguccggg uacaagacgc ucaccgccua cuucaccaac uaccgcguga     2460

ccagcgacaa caagguccag uacgacgugg uguuccacgg cguccugacg gacaacgccg     2520

acaucagcaa caacaaggcg ccgaucgcca aggugaccgg gcccuccacc ggcgccgugg     2580

gccggaacau cgaguucagc gggaaggacu ccaaggacga ggacggcaag aucgucagcu     2640

acgacuggga cuucggggac ggcgccaccu cccgcgggaa gaacagcgug cacgcguaca     2700

agaaggccgg cacguacaac gugacccuga aggucaccga cgacaagggc gccaccgcca     2760

cggaguccuu caccaucgag aucaagaacg aggacaccac cacgcccauc accaaggaga     2820

uggagcccaa cgacgacauc aaggaggcca acgggccgau cguggagggc gugaccguca     2880

agggggaccu caacggcagc gacgacgcgg acaccuucua cuucgacgug aaggaggacg     2940

gggacgugac gaucgagcug cccuacuccg gcagcuccaa cuucaccugg cuggucuaca     3000

aggagggcga cgaccagaac cacaucgcca gcgggaucga caagaacaac uccaaggugg     3060

gcaccuucaa gagcaccaag gggcggcacu acguguucau cuacaagcac gacuccgcca     3120

gcaacaucuc cuacagccuc aacaucaagg gccuggggaa cgagaagcug aaggagaagg     3180

agaacaacga cuccagcgac aaggccacgg ucauccccaa cuucaacacc accaugcagg     3240

gcagccuccu gggcgacgac ucccgcgacu acuacagcuu cgaggugaag gaggaggggg     3300

aggugaacau cgagcuggac aagaaggacg aguucggcgu caccuggacg cuccaccccg     3360

aguccaacau caacgaccgg aucaccuacg gccaggugga cgggaacaag gugagcaaca     3420

aggucaagcu gcgcccgggc aaguacuacc ugcucgugua caaguacucc gggagcggca     3480

acuacgagcu gcgggugaac aagugaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  7155
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt11)

<400>  7155
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuga agaucauccu caaccgcggc aagaccauga      120

agcggaagug ccugagcaag cgccugaugc ucgccaucac cauggccacg aucuucaccg      180

ugaacuccac ccugcccauc uacgcggccg ucgacaagaa caacgccacc gccgccgugc      240

agaacgagag caagcgguac acgguguccu accugaagac ccucaacuac uacgaccugg      300

ucgaccugcu cgugaagacc gagaucgaga accugccgga ccuguuccag uacagcuccg      360

acgcgaagga guucuacggg aacaagaccc gcaugagcuu caucauggac gagaucggcc      420

ggcgcgcgcc ccaguacacg gagaucgacc acaaggggau ccccacccuc guggaggucg      480

ugcgggccgg cuucuaccug ggguuccaca acaaggagcu gaacgagauc aacaagcgcu      540

ccuucaagga gcgggugauc cccagcaucc ucgccaucca gaagaacccg aacuucaagc      600

ugggcaccga gguccaggac aagaucgugu ccgccaccgg ccugcucgcc gggaacgaga      660

cggccccgcc cgaggugguc aacaacuuca cccccauccu gcaggacugc aucaagaaca      720

ucgaccgcua cgcccuggac gaccucaaga gcaaggcccu guucaacgug cuggcggccc      780

cgaccuacga caucaccgag uaccuccggg ccacgaagga gaagcccgag aacacccccu      840

gguacggcaa gaucgacggg uucaucaacg agcugaagaa gcuggcccuc uacggcaaga      900

ucaacgacaa caacuccugg aucaucgaca acgggaucua ccacaucgcg ccccugggca      960

agcugcacag caacaacaag aucggcaucg agacccucac cgaggugaug aaggucuacc     1020

cguaccuguc caugcagcac cuccagagcg ccgaccagau caagcgccac uacgacucca     1080

aggacgccga ggggaacaag aucccccugg acaaguucaa gaaggagggc aaggagaagu     1140

acugccccaa gacguacacc uucgacgacg ggaaggugau caucaaggcc ggcgcccggg     1200

uggaggagga gaaggucaag cgccuguacu gggccagcaa ggaggugaac ucccaguucu     1260

uccgggugua cggcaucgac aagccccugg aggaggggaa cccggacgac auccucacca     1320

uggucaucua caacagcccc gaggaguaca agcugaacuc cgugcuguac ggcuacgaca     1380

ccaacaacgg gggcauguac aucgagcccg aggggacguu cuucaccuac gagcgcgagg     1440

cgcaggagag caccuacacc cucgaggagc uguuccggca cgaguacacg cacuaccugc     1500

agggccgcua cgccgugccc ggccaguggg ggcggaccaa gcucuacgac aacgaccgcc     1560

ugaccuggua cgaggagggc ggggccgagc uguucgccgg cagcacccgg acguccggga     1620

uccucccgcg caagagcauc gucuccaaca uccacaacac cacccgcaac aaccgguaca     1680

agcugagcga caccgugcac uccaaguacg gcgccagcuu cgaguucuac aacuacgcgu     1740

gcauguucau ggacuacaug uacaacaagg acaugggcau ccugaacaag cucaacgacc     1800

uggccaagaa caacgacguc gacggguacg acaacuacau ccgcgaccug uccagcaacu     1860

acgcccugaa cgacaaguac caggaccaca ugcaggagcg gaucgacaac uacgagaacc     1920

ucacggugcc cuucguggcc gacgacuacc ugguccgcca cgcguacaag aaccccaacg     1980

agaucuacuc cgagaucagc gagguggcca agcugaagga cgccaagucc gaggugaaga     2040

agucccagua cuucagcacc uucacccucc ggggcagcua caccgggggc gccuccaagg     2100

ggaagcugga ggaccagaag gccaugaaca aguucaucga cgacagccug aagaagcucg     2160

acaccuacuc cuggagcggc uacaagacgc ugaccgcgua cuucaccaac uacaaggucg     2220

acuccagcaa ccgcgugacc uacgacgugg ucuuccacgg cuaccugccc aacgaggggg     2280

acagcaagaa cucccucccg uacggcaaga ucaacgggac guacaagggc accgagaagg     2340

agaagaucaa guucagcucc gagggcagcu ucgaccccga cgggaagauc guguccuacg     2400

agugggacuu cggcgacggg aacaagagca acgaggagaa ccccgagcac uccuacgaca     2460

aggugggcac cuacaccguc aagcugaagg ugacggacga caagggggag agcuccguga     2520

gcaccaccac cgccgagauc aaggaccugu ccgagaacaa gcuccccguc aucuacaugc     2580

acgugcccaa gagcggcgcc cugaaccaga agguggucuu cuacggcaag gggacguacg     2640

accccgacgg cuccaucgcc ggguaccagu gggacuucgg cgacgggagc gacuucucca     2700

gcgagcagaa ccccucccac guguacacca agaagggcga guacaccgug acccugcggg     2760

ucauggacag cagcggccag auguccgaga agacgaugaa gaucaagauc accgacccgg     2820

uguaccccau cgggaccgag aaggagccca acaacagcaa ggagaccgcc uccggcccca     2880

ucgugccggg gauccccguc agcggcacga ucgagaacac cuccgaccag gacuacuucu     2940

acuucgacgu gaucaccccc ggggagguga agaucgacau caacaagcuc ggcuacggcg     3000

gggcgaccug ggucguguac gacgagaaca acaacgccgu gagcuacgcc acggacgacg     3060

gccagaaccu guccgggaag uucaaggccg acaagcccgg ccgcuacuac auccaccugu     3120

acauguucaa cgggagcuac augccguacc ggaucaacau cgagggcucc gucggccgcu     3180

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  7156
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt11)

<400>  7156
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagcgcaagu gccugagcaa gcggcucaug cuggccauca      120

ccauggccac caucuucacg gugaacucca cccugcccau cuacgcggcc gucgacaaga      180

acaacgccac cgccgccgug cagaacgaga gcaagcgcua caccgugucc uaccucaaga      240

cgcugaacua cuacgaccug gucgaccucc uggugaagac cgagaucgag aaccugccgg      300

accucuucca guacagcucc gacgcgaagg aguucuacgg caacaagacc cggaugagcu      360

ucaucaugga cgagaucggg cgccgggcgc cccaguacac cgagaucgac cacaagggca      420

uccccacgcu gguggagguc gugcgcgccg gguucuaccu gggcuuccac aacaaggagc      480

ucaacgagau caacaagcgg uccuucaagg agcgcgugau ccccagcauc cuggccaucc      540

agaagaaccc gaacuucaag cuggggaccg agguccagga caagaucgug uccgccaccg      600

gccuccuggc cggcaacgag accgccccgc ccgagguggu caacaacuuc acgcccaucc      660

ugcaggacug caucaagaac aucgaccggu acgcccucga cgaccucaag agcaaggccc      720

uguucaacgu gcucgcggcc ccgaccuacg acaucaccga guaccugcgc gccaccaagg      780

agaagcccga gaacacgccc ugguacggga agaucgacgg cuucaucaac gagcugaaga      840

agcucgcccu guacgggaag aucaacgaca acaacuccug gaucaucgac aacggcaucu      900

accacaucgc gccccugggg aagcuccaca gcaacaacaa gaucggcauc gagacccuga      960

ccgaggugau gaaggucuac ccguaccugu ccaugcagca ccuccagagc gccgaccaga     1020

ucaagcggca cuacgacucc aaggacgccg agggcaacaa gaucccccug gacaaguuca     1080

agaaggaggg gaaggagaag uacugcccca agaccuacac guucgacgac ggcaagguga     1140

ucaucaaggc cggggcccgc guggaggagg agaaggucaa gcggcuguac ugggccagca     1200

aggaggugaa cucccaguuc uuccgcgugu acggcaucga caagccccuc gaggagggca     1260

acccggacga cauccugacc auggucaucu acaacagccc cgaggaguac aagcugaacu     1320

ccgugcucua cggguacgac accaacaacg gcgggaugua caucgagccc gagggcaccu     1380

ucuucacgua cgagcgggag gcgcaggaga gcaccuacac ccuggaggag cuguuccgcc     1440

acgaguacac ccacuaccuc caggggcggu acgccgugcc cggccagugg ggccgcacga     1500

agcuguacga caacgaccgg cugaccuggu acgaggaggg cggggccgag cuguucgccg     1560

ggagcacccg caccuccggc auccugccgc gcaagagcau cgucuccaac auccacaaca     1620

cgacccggaa caaccgcuac aagcugagcg acaccgugca cuccaaguac ggggccagcu     1680

ucgaguucua caacuacgcg ugcauguuca uggacuacau guacaacaag gacaugggca     1740

uccucaacaa gcugaacgac cuggccaaga acaacgacgu cgacggcuac gacaacuaca     1800

uccgggaccu cuccagcaac uacgcccuga acgacaagua ccaggaccac augcaggagc     1860

gcaucgacaa cuacgagaac cugaccgugc ccuucguggc cgacgacuac cugguccggc     1920

acgcguacaa gaaccccaac gagaucuacu ccgagaucag cgagguggcc aagcucaagg     1980

acgccaaguc cgaggugaag aagucccagu acuucagcac guucacccug cgcgggagcu     2040

acaccggcgg ggccuccaag ggcaagcugg aggaccagaa ggccaugaac aaguucaucg     2100

acgacagccu caagaagcug gacaccuacu ccuggagcgg guacaagacc cugacggcgu     2160

acuucaccaa cuacaagguc gacuccagca accgggugac cuacgacgug gucuuccacg     2220

gcuaccuccc caacgagggc gacagcaaga acucccugcc guacgggaag aucaacggca     2280

ccuacaaggg gacggagaag gagaagauca aguucagcuc cgagggcagc uucgaccccg     2340

acggcaagau cguguccuac gagugggacu ucggggacgg caacaagagc aacgaggaga     2400

accccgagca cuccuacgac aaggugggga ccuacaccgu caagcugaag gugaccgacg     2460

acaagggcga gagcuccgug agcacgacca ccgccgagau caaggaccuc uccgagaaca     2520

agcugcccgu caucuacaug cacgugccca agagcggggc ccugaaccag aagguggucu     2580

ucuacggcaa gggcaccuac gaccccgacg gguccaucgc cggcuaccag ugggacuucg     2640

gggacggcag cgacuucucc agcgagcaga accccuccca cguguacacg aagaaggggg     2700

aguacaccgu gacccuccgc gucauggaca gcagcggcca gauguccgag aagaccauga     2760

agaucaagau cacggacccg guguacccca ucggcaccga gaaggagccc aacaacagca     2820

aggagaccgc cuccgggccc aucgugccgg gcauccccgu cagcgggacc aucgagaaca     2880

cguccgacca ggacuacuuc uacuucgacg ugaucacccc cggcgaggug aagaucgaca     2940

ucaacaagcu gggguacggc ggcgcgaccu gggucgugua cgacgagaac aacaacgccg     3000

ugagcuacgc caccgacgac gggcagaacc uguccggcaa guucaaggcc gacaagcccg     3060

ggcgguacua cauccaccuc uacauguuca acggcagcua caugccguac cgcaucaaca     3120

ucgagggguc cgucggccgg ugaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  7157
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt11)

<400>  7157
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccugcuguuc cuguucucca      120

gcgccuacuc cguccagaac gagagcaagc gcuacaccgu guccuaccug aagacgcuca      180

acuacuacga ccugguggac cugcucguca agaccgagau cgagaaccug cccgaccugu      240

uccaguacag cuccgacgcc aaggaguucu acggcaacaa gacccggaug agcuucauca      300

uggacgagau cgggcgccgg gcgccgcagu acaccgagau cgaccacaag ggcaucccca      360

cgcucgugga ggugguccgc gccggguucu accugggcuu ccacaacaag gagcugaacg      420

agaucaacaa gcgguccuuc aaggagcgcg ugauccccag cauccucgcc auccagaaga      480

accccaacuu caagcugggg accgaggugc aggacaagau cgucuccgcc accggccugc      540

ucgccggcaa cgagaccgcg ccgcccgagg uggugaacaa cuucacgccc auccugcagg      600

acugcaucaa gaacaucgac cgguacgccc uggacgaccu caagagcaag gcccuguuca      660

acguccuggc cgcgcccacc uacgacauca ccgaguaccu ccgcgccacc aaggagaagc      720

cggagaacac gcccugguac gggaagaucg acggcuucau caacgagcug aagaagcugg      780

cccucuacgg gaagaucaac gacaacaacu ccuggaucau cgacaacggc aucuaccaca      840

ucgcgccccu ggggaagcug cacagcaaca acaagaucgg caucgagacc cucaccgagg      900

ugaugaaggu guaccccuac cuguccaugc agcaccucca gagcgccgac cagaucaagc      960

ggcacuacga cuccaaggac gccgagggca acaagauccc gcucgacaag uucaagaagg     1020

aggggaagga gaaguacugc cccaagaccu acacguucga cgacggcaag gucaucauca     1080

aggccggggc ccgcguggag gaggagaagg ugaagcggcu guacugggcc agcaaggagg     1140

ucaacuccca guucuuccgc guguacggca ucgacaagcc ccuggaggag ggcaaccccg     1200

acgacauccu caccauggug aucuacaaca gcccggagga guacaagcug aacagcgucc     1260

uguacgggua cgacaccaac aacggcggga uguacaucga gcccgagggc accuucuuca     1320

cguacgagcg ggaggcccag gaguccaccu acacccucga ggagcuguuc cgccacgagu     1380

acacccacua ccugcagggg cgguacgcgg ugcccggcca guggggccgc acgaagcucu     1440

acgacaacga ccggcugacc ugguacgagg agggcggggc cgagcuguuc gccgggagca     1500

cccgcaccuc cggcauccuc ccccgcaaga gcaucguguc caacauccac aacacgaccc     1560

ggaacaaccg guacaagcug agcgacaccg uccacuccaa guacggggcc agcuucgagu     1620

ucuacaacua cgccugcaug uucauggacu acauguacaa caaggacaug ggcauccuga     1680

acaagcucaa cgaccuggcg aagaacaacg acguggacgg cuacgacaac uacauccgcg     1740

accuguccag caacuacgcc cucaacgaca aguaccagga ccacaugcag gagcgcaucg     1800

acaacuacga gaaccugacc gucccguucg uggccgacga cuaccuggug cggcacgccu     1860

acaagaaccc caacgagauc uacuccgaga ucagcgaggu cgccaagcug aaggacgcga     1920

aguccgaggu gaagaagucc caguacuuca gcacguucac ccuccgcggg agcuacaccg     1980

gcggggccuc caagggcaag cuggaggacc agaaggccau gaacaaguuc aucgacgaca     2040

gccugaagaa gcucgacacc uacuccugga gcggguacaa gacgcugacc gccuacuuca     2100

ccaacuacaa gguggacagc uccaaccggg ucaccuacga cgugguguuc cacggcuacc     2160

ugcccaacga gggcgacagc aagaacuccc uccccuacgg gaagaucaac ggcaccuaca     2220

aggggacgga gaaggagaag aucaaguuca gcuccgaggg cagcuucgac ccggacggca     2280

agaucgucuc cuacgagugg gacuucgggg acggcaacaa gagcaacgag gagaaccccg     2340

agcacuccua cgacaaggug gggaccuaca ccgugaagcu gaaggucacc gacgacaagg     2400

gcgagagcuc cgugagcacg accaccgcgg agaucaagga ccuguccgag aacaagcucc     2460

ccgugaucua caugcacguc cccaagagcg gggcccugaa ccagaaggug guguucuacg     2520

gcaagggcac cuacgacccg gacgggucca ucgccggcua ccagugggac uucggggacg     2580

gcagcgacuu cuccagcgag cagaacccca gccacgucua cacgaagaag ggggaguaca     2640

ccgugacccu gcgcgugaug gacuccagcg gccagauguc cgagaagacc augaagauca     2700

agaucacgga ccccgucuac ccgaucggca ccgagaagga gcccaacaac agcaaggaga     2760

ccgccuccgg gcccaucgug cccggcaucc cggugagcgg gaccaucgag aacacguccg     2820

accaggacua cuucuacuuc gacgucauca cccccggcga ggugaagauc gacaucaaca     2880

agcucgggua cggcggcgcc accugggugg ucuacgacga gaacaacaac gcggugagcu     2940

acgccaccga cgacgggcag aaccuguccg gcaaguucaa ggccgacaag cccgggcggu     3000

acuacaucca ccuguacaug uucaacggca gcuacaugcc cuaccgcauc aacaucgagg     3060

gguccguggg ccggugagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  7158
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt11)

<400>  7158
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaguggguga ccuucaucag ccucuuauuc cuguuuucca      120

gugccuacuc caugaagcgc aagugccuga gcaagcggcu caugcuggcc aucaccaugg      180

cgacgaucuu caccgucaac uccacccugc ccaucuacgc cgccguggac aagaacaacg      240

ccaccgccgc gcgccggcgc cggaagcgcg ugcagaacga gagcaagcgg uacacggucu      300

ccuaccucaa gacccugaac uacuacgacc ugguggaccu ccuggugaag accgagaucg      360

agaaccugcc ggaccucuuc caguacagcu cagacgccaa ggaguucuac ggcaacaaga      420

cccgcaugag cuucaucaug gacgagaucg ggcggcgcgc gccccaguac acggagaucg      480

accacaaggg cauucccacc cuggucgagg uggugcgggc cggguucuac cugggcuucc      540

acaacaagga gcucaaugag aucaacaagc gcuccuucaa ggagcgaguc aucccaagca      600

uccuggccau ccagaagaac ccgaacuuca agcuggggac cgaggugcag gacaagaucg      660

uguccgccac cggccuccuc gccggcaacg agacggcccc gcccgagguc gugaauaacu      720

ucacccccau ccugcaggac ugcaucaaga acaucgaccg cuacgcccuc gacgaccuca      780

agagcaaggc gcuguucaac guccuggcag ccccgacaua cgacaucacc gaguaccucc      840

gggccacuaa ggagaagccc gagaacaccc ccugguacgg gaagaucgac ggcuucauca      900

acgagcugaa gaaacucgcc cuguacggga agaucaacga caacaacucc uggaucaucg      960

acaacggcau cuaccacauc gcgccccugg ggaagcucca cagcaacaac aagaucggca     1020

ucgagaccuu gaccgagguc augaaggugu acccguaccu guccaugcag caccuccaaa     1080

gcgccgacca gaucaagcgc cacuacgacu ccaaggacgc cgagggcaac aagauccccc     1140

uugacaaguu caagaaggag gggaaggaga aauacugccc caagacguac accuucgacg     1200

acggcaaggu gaucaucaag gccggggccc gggucgagga ggagaaggug aagcgguuau     1260

acugggcguc aaaagaggug aacagccagu ucuuccgggu cuacggcauc gacaagcccc     1320

ucgaggaggg caacccggac gacauccuga ccauggugau cuacaacucc cccgaggagu     1380

acaagcugaa cagcgugcuc uacggguacg acacaaacaa cggcggaaug uacaucgagc     1440

ccgagggcac guucuucacg uacgagcgcg aggcccagga guccaccuac acccuggagg     1500

agcuguuccg gcacgaguac acgcacuacc uccaggggag auacgccguc cccggccagu     1560

ggggccgcac caagcuguac gacaacgacc ggcugaccug guacgaggag ggaggggccg     1620

agcuguucgc cgggagcacc cgcacguccg gcauccugcc gcgcaagagc aucguuucca     1680

acauccauaa caccacccgg aacaacagau acaagcugag cgacaccguc cacuccaagu     1740

acggggcgag cuucgaguuu uacaacuacg ccuguauguu cauggacuac auguacaaca     1800

aggauauggg cauacucaac aagcugaacg accuggccaa gaauaacgac guggacggcu     1860

acgacaacua cauccgcgac cugucaagca acuacgcccu caacgacaag uaccaggacc     1920

acaugcagga gcggaucgac aacuacgaga accugacggu gcccuucguc gcggacgacu     1980

accuggugcg ucacgccuac aagaacccca acgagaucua cucugagauc agugaggugg     2040

ccaagcucaa ggacgccaag ucagagguca agaaguccca guacuucagc accuucaccc     2100

ugcgggggag cuauaccggc ggggccucca agggcaagcu ggaggaccag aaggccauga     2160

acaaguucau cgacgacagc cucaagaagc uggacaccua cagcuggucc ggguacaaga     2220

cgcugaccgc guacuucacc aacuacaagg uggauagcuc caaccgcgua accuacgacg     2280

ucguguucca cggcuaccuc cccaacgagg gcgacagcaa gaacucccug ccguacggga     2340

agaucaacgg cacguacaag gggaccgaga aggagaaaau caaguucagc uccgagggcu     2400

ccuucgaccc cgacggcaag aucguguccu acgaguggga cuucggggac ggcaacaaga     2460

gcaacgagga gaaccccgaa cacuccuacg acaaggucgg gaccuacacc gugaagcuga     2520

aggugacgga cgacaagggc gagagcuccg ucucuaccac caccgccgag aucaaggacc     2580

ucuccgagaa caagcugccc gugaucuaca ugcacgugcc caagucaggg gcccugaacc     2640

aaaaggucgu guuuuacggc aagggcacgu acgaccccga cggguccaua gccggcuacc     2700

agugggacuu cggggacggc agcgacuuca gcuccgagca gaaccccagc cacguguaca     2760

ccaagaaggg ggaguacacc gucacccuca gggugaugga cuccagcggc cagauguccg     2820

agaagacgau gaagaucaag aucaccgauc cgguguaccc caucggcacc gagaaggagc     2880

cgaacaacag caaggagacc gcguccgggc ccaucguccc gggcaucccc gugagcggga     2940

cgaucgagaa caccuccgac caggacuacu ucuacuucga cgugaucacc cccggcgagg     3000

ucaagaucga uaucaacaag cugggguacg gcggcgccac cuggguggug uacgacgaga     3060

acaacaacgc cgucagcuac gcuacggacg acgggcagaa ccuguccggc aaguucaagg     3120

ccgacaagcc cgggcgguac uacauccacc ucuacauguu caacggcagc uacaugccgu     3180

accggaucaa caucgagggg uccguaggcc gaugaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  7159
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt11)

<400>  7159
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uacuauucgc cugccuccuc ggcgccgccu      120

ucgccaugcc ccuacccccc caccccggcc accccggcua caucaacuuc ucauacgaag      180

uccucacccc ccucaaaugg uaccaaucaa uccgcccccc cuaccccucc uacggcuacg      240

aacccauggg aggcuggcuc caccaccaaa ucauccccgu ccucucccaa caacaccccc      300

ccacccacac ccuccaaccc caccaccaca uccccgucgu ccccgcccaa caacccguca      360

ucccccaaca acccaugaug cccguccccg gccaacacuc aaugaccccc auccaacacc      420

accaacccaa ccuccccccc cccgcccaac aacccuacca accccaaccc guccaacccc      480

aaccacacca accaaugcaa ccccaacccc ccguccaccc caugcaaccc cucccccccc      540

aacccccccu accccccaug uuccccaugc aaccccuccc ccccaugcuc cccgaccuca      600

cccucgaagc cuggcccucc accgacaaaa ccaaacgcga agaagucgac uaaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  7160
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt11)

<400>  7160
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccccucaaau gguaccaauc cauccgcccc cccuaccccu      180

ccuacggcua cgaacccaug ggcggcuggu aaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  7161
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt11)

<400>  7161
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccccucaaau gguaccaauc cauccgcccc ccccccaugc      180

uccccgaccu cacccucgaa gccuggcccu ccaccgacaa aaccaaacgc gaagaagucg      240

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  7162
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt11)

<400>  7162
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccaa accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca ccccccucaa augguaccaa uccauccgcc      240

cccccuaccc cuccuacggc uacgaaccca ugggcggcug guaaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  7163
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt11)

<400>  7163
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccua cuccucuccg      120

gcgcccucgc ccucacccaa accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca ccccccucaa augguaccaa uccauccgcc      240

ccccccccau gcuccccgac cucacccucg aagccuggcc cuccaccgac aaaaccaaac      300

gcgaagaagu cgacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  7164
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt11)

<400>  7164
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccucguc ggcgccgccu      120

ucgcaaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc acucaaaugg uaccaaucca ugauccgccc acccuacuca uccuacggcu      240

acgaaccaau gggcggcugg cuccaccacc aaaucauccc cgucguaucc caacaacacc      300

cccucaccca cacccuccaa ucccaccacc acauccccgu cguccccgca caacaacccc      360

gcguccgcca acaagcccuc augcccgucc ccggccaaca auccaugacc cccacccaac      420

accaccaacc caaccucccc cuccccgccc aacaacccuu ccaaccccaa cccguccaac      480

cccaacccca ccaacccaug caaccccaac ccccagucca acccaugcaa ccccuccucc      540

cccaaccccc ccuccccccc auguucccac uccgaccccu cccccccauc cuacccgacc      600

uccaccuuga agccuggccc gccaccgaca aaaccaaaca agaagaaguc gacuaaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  7165
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt11)

<400>  7165
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccccucaaau gguaccaauc caugauccgc ccccccuacu      180

ccuccuacgg cuacgaaccc augggcggcu gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  7166
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt11)

<400>  7166
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccccucaaau gguaccaauc caugauccgc ccccccccca      180

uccuccccga ccuccaccuc gaagccuggc ccgccaccga caaaaccaaa caagaagaag      240

ucgacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  7167
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt11)

<400>  7167
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccaa accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca ccccccucaa augguaccaa uccaugaucc      240

gcccccccua cuccuccuac ggcuacgaac ccaugggcgg cugguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  7168
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt11)

<400>  7168
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccaa accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca ccccccucaa augguaccaa uccaugaucc      240

gccccccccc cauccucccc gaccuccacc ucgaagccug gcccgccacc gacaaaacca      300

aacaagaaga agucgacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  7169
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt11)

<400>  7169
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugucuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaaaca ugauccgaca ccccuacacc uccuacggcu      240

acgaacccau gggcggcugg cuccaccacc aaaucauccc cgucgucucc caacaaaccc      300

cccaauccca cgcccuucaa ccccaccacc acauccccau gguccccgcc caacaacccg      360

gcauacccca acaacccaug augccccucc cuggccaaca cuccaugacc cccacccaac      420

accaccaacc caaccucccc cuccccgccc aacaacccuu ccaaccccaa cccguccaac      480

cccaacccca ccaaccccuc caaccccaau cccccaugca ccccauccaa ccccuccucc      540

cccaaccacc ccuacccccc auguucucca ugcaaucccu ccuccccgac cucccccucg      600

aagccuggcc cgccaccgac aaaacaaaac gugaagaagu cgacuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  7170
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt11)

<400>  7170
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccccucaaau gguaccaaaa caugauccgc caccccuaca      180

ccuccuacgg cuacgaaccc augggcggcu gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  7171
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt11)

<400>  7171
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuccccc cccaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccccucaaau gguaccaaaa caugauccgc caccccuccc      180

uccuccccga ccucccccuc gaagccuggc ccgccaccga caaaaccaaa cgcgaagaag      240

ucgacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  7172
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt11)

<400>  7172
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccaa accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca ccccccucaa augguaccaa aacaugaucc      240

gccaccccua caccuccuac ggcuacgaac ccaugggcgg cugguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  7173
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt11)

<400>  7173
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgucaugg ccccccgcac ccucguccuc cuccucuccg      120

gcgcccucgc ccucacccaa accugggcca ugccccuccc cccccacccc ggccaccccg      180

gcuacaucaa cuucuccuac gaaguccuca ccccccucaa augguaccaa aacaugaucc      240

gccaccccuc ccuccucccc gaccuccccc ucgaagccug gcccgccacc gacaaaacca      300

aacgcgaaga agucgacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  7174
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt11)

<400>  7174
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggaua caucaacuuc uccuacaucc      180

gacaccccua caccuccuac ggcuacgaac ccaugggcgg cuggcuccac caccaaauca      240

uccccgucgu cucccaacaa accccccaau cccacgcccu ccaaccacac caccacaucc      300

ccaugguccc cgcccaacaa cccggcaucc cccaacaacc caugaugccc cuccccggcc      360

aacacuccau gacccccacc caacaccacc aacccaaccu cccccuuccc gcccaacaac      420

ccuuccaacc ccaacccguc caaccccaac cccaccaacc ccuacaaccc caauccccca      480

ugcaccccau ccaaccccuc cucccccaac ccccccuacc ccccauguuc uccaugcaau      540

cccuccuccc cgaccucccc cucgaagccu ggcccgccac cgacaaaacc aaacgcgaag      600

aagucgacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  7175
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt11)

<400>  7175
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga ucuucuucgc cugccuccuc ggcgccuccc      120

ucgccaugcc ccucccaccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacacc ccucaaaugg uaccaaaaca ugauccgcca ccccuacacc uccuacggcu      240

acgaacccau gggcggcugg cuccaccacc aaaucauccc cgucgucucu caacaaacac      300

cccaauccca cgcccuccaa ccccaccacc acauccccau gguccccgcc caacaacccg      360

gcauacccca acaacccaug augccccucc ccggccaaca cuccaugacc cccacccaac      420

accaccaacc caaccucccc cuccccgccc aacaacccuu ccaaccccaa cccguccaac      480

cccaacccca ccaaccccuc caaccccaau cccccaugca ccccauccaa ccccuacucc      540

cccaaccacc ccuaccaccc auguucucca ugcaaucccu ccuccccgac cucccccucg      600

aagccuggcc cgccaccgac aaaaccaaac gcgaagaagu cgacuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  7176
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt11)

<400>  7176
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggcgccgccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc ccucaaaugg uaccaaaaca ugauccgcca ccccucccuc cuccccgacc      240

ucccccucga agccuggccc gccaccgaca aaaccaaacg cgaagaaguc gacuaaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  7177
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt11)

<400>  7177
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaccugga uccucuucgc cugccuccuc ggagccgccu      120

ucuccaugcc ccuacccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

accuuuaccu cgaagccauc cgcaucgacc gcaccgccuu cguccucacc ccccuaaaau      240

gguaccaaaa caugauccgc caccccuaca ccuccuacgg cuacgaaccc augggcggcu      300

ggcuccacca ccaaaucauc cccgucgucu cccaacaaac cccccaaucc cacgcccucc      360

aaccccacca ccacaucccc augguccccg cccaacaacc cggcaucccc caacaaccca      420

ugaugccccu ccccggccaa cacuccauga cccccaccca acaccaccaa cccaaccucc      480

cccuccccgc ccaacaaccc uuccaacccc aacccguaca accccagccc caccaacccc      540

uucaacccca aucccccaug caccccaucc aaccccuccu cccccaaccc ccccuacccc      600

ccauguucuc caugcaaucc cuccuccccg accucccccu cgaagccugg cccgccaccg      660

acaaaaccaa acgcgaagaa gucgacuaag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  7178
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt11)

<400>  7178
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaccugga uccucuucgc cugccuccuc ggcgcagccu      120

ucuccaugcc ccuccccccc caccccggcc accccggcua caucaacuuc uccuacgaag      180

uccucacccc ccuaaaaugg uaccaaaaca ugauccgcca ccccacaccc caaucacacg      240

cccuccaacc ccaccaccac auccccaugg uccccgcaca acaacccggc aucccccaac      300

aacccaugau gccccucccc ggccaacacu ccaugacacc cacccaacac caccaaccca      360

accuaccccu ccccgcccaa caacccuucc aaccccaacc cguccaaccc caaccccacc      420

aaccccucca accccaaucc cccaugcacc ccauccaacc ccuccucccc caaccccccc      480

ucccacccau guucuccaug caaucccucc uccccgaccu cccacucgaa gccuggcccg      540

ccaccgacaa aaccaaacgc gaagaagucg acuaaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  7179
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt11)

<400>  7179
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccccuacccc cacaccccgg ccaccccggc uacaucaacu      120

ucuccuacga aguccucacc ccacucaaau gguaccaaaa caugauccgc caccccuaca      180

ccuccuacgg cuacgaaccc augggcggcu ggcuccacca ccaaaucauc cccgucgucu      240

cccaacaaac cccacaaucc cacgcccucc aaccccacca ccacaucccc augguccccg      300

cccaacaacc cggcaucccc caacaaccca ugaugccccu ccccggccaa cacuccauga      360

cccccaccca acaccaccaa cccaaccuac cccuccccgc ccaacaaccc uuccaacccc      420

aaccagucca accccaaccc caccaacccc uccaacccca aucccccaug cacccaaucc      480

aaccccuacu cccccaaccu ccccuaccac ccauguucuc caugcaaucc cuccuccccg      540

accucccccu cgaagccugg cccgccaccg acaaaaccaa acgcgaagaa gucgacuaag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  7180
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt11)

<400>  7180
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaggaguug cccgccuacc acuacuacua ggucuccucu      120

uacucccgcg acccggccgc ccacucgacc uagcagacua cacauacgac cucgcagaag      180

aagacgacuc agaaccacua aacuacaaag aucccugcaa agccgcggca uuccucggag      240

acauagcccu ggacgaagaa gaucuacgag cauuccaggu ccaacaagca guagaccucc      300

ggcgacacac agcucgcaaa ucguccauca aagcggccgu cccaggcaac acaaguaccc      360

cuuccugcca guccaccaac ggucaacccc aacggggagc cugcggacgc uggcguggca      420

ggucacgauc ccggcgagca gccaccagca gaccggaacg aguauggccc gacgggguca      480

ucccauucgu aaucgguggg aacuucacgg gaucgcaacg agcaguauuc cgacaggcca      540

ugcgccacug ggaaaaacac acaugcguca ccuuccucga acgcacagac gaagacagcu      600

acauagucuu cacauacaga ccaugcggau gcugcaguua cgucggacgg agaggcggcg      660

gcccgcaagc aauaucgaua gggaaaaacu gcgacaaauu cggcauaguc guccacgaac      720

uagggcaugu cguaggguuc uggcacgagc acaccaggcc cgaccgagac cgccacguaa      780

gcauaguccg cgaaaacauc caacccggac aggaauacaa cuuccucaag auggaacccc      840

aagaagucga gucgcugggg gaaacauacg acuucgacuc cauaaugcac uacgcccgaa      900

acaccuucag ccgagguauc uuccucgaca caaucguccc caaguacgaa gucaacggcg      960

ucaaaccccc aauaggccaa cggacccgac ucucaaaagg ugacaucgcu caggcccgca     1020

aacuguauaa gugccccgcc uguggggaga cccuacagga cagcacgggc aacuucagcu     1080

ccccugaaua ccccaacggc uacagcgcac acaugcacug cgucuggcgc aucaguguca     1140

ccccaggaga gaaaaucauc cucaacuuca ccucacucga ucucuaccga agcagacucu     1200

guugguacga cuacguggag guccgagacg gguucuggcg caaagcaccg cuccgcggcc     1260

gcuucugcgg cucuaaacuu cccgaaccca uugucagcac cgacucgaga cucugggucg     1320

aguucaggag uuccagcaac uggguaggca aaggauucuu ugcagucuac gaagccauau     1380

gcggcggcga cgucaagaaa gacuacggcc acauccaguc cccaaacuac ccagacgacu     1440

accgccccuc caaagucugc auauggagga uacaaguauc agaaggguuu cacgucggac     1500

ugacauucca aaguuucgaa auagaacguc acgacucaug cgcguacgac uaccuggaag     1560

uacgcgacgg ccauuccgaa agcagcacac uaauaggccg guacuguggc uacgaaaagc     1620

ccgacgacau aaaaucaaca ucaagcagac uguggcuaaa guucgucucg gacggaagca     1680

uaaacaaagc aggauucgca gugaacuucu uuaaggaagu cgacgaaugu ucgcgcccaa     1740

acaggggagg cugcgaacaa agaugccuua acacacuggg gucauauaag ugcagcugcg     1800

accccggaua cgagcuugca ccagacaagc gaagauguga ggccgccugc ggaggcuucc     1860

ucacaaaacu gaacggaucc aucacaucac ccggauggcc aaaagaguau cccccgaaua     1920

aaaacugcau auggcagcua guagcgccaa cccaauaccg gaucagccuc caguucgacu     1980

ucuucgaaac cgaaggcaac gacgugugca aauacgacuu cgucgaggua cgcagcgguc     2040

uuaccgcgga cucaaaacug cacggcaaau ucugcggcag cgaaaaacca gaaguaauca     2100

ccagccaaua caacaacaug agagucgaau uuaaaucaga caacaccgua uccaagaaag     2160

gcuucaaagc ccacuucuuu uccgauaaag acgaaugcag uaaagauaac gggggcuguc     2220

agcaagacug cguuaacaca uucggaagcu acgaauguca augccgcagu ggguucgugc     2280

ugcacgacaa caaacacgac ugcaaagaag caggaugcga ccauaaaguc accagcacaa     2340

gcggaacgau cacuagcccc aacuggccgg acaaauaccc auccaagaaa gaaugcacau     2400

gggccaucuc cagcaccccc ggccaccgcg ucaaauuaac auucauggag auggacaucg     2460

aaucacaacc cgaaugcgcc uacgaccacc uggagguauu cgacggccga gacgccaaag     2520

caccagugcu cggccgcuuc ugcggcucca agaaaccaga accagugcua gccaccggca     2580

gucgaauguu ccuccgcuuc uacagugaca acaguguaca acgaaaagga uuccaagcaa     2640

gccacgcaac agaaugcggu ggccaagucc gggccgacgu caaaacaaaa gaccuauacu     2700

cacaugcuca auucggugac aacaacuacc cgggcggugu agacugcgaa ugggucaucg     2760

ucgcagaaga gggauacggg gucgaacucg uguuccaaac auucgaaguc gaggaagaga     2820

cagauugugg cuacgacuac auggaacucu ucgacgggua cgacagcacc gcccccagac     2880

uaggccgcua cuguggauca gguccacccg aagaagucua cagcgccggu gacucaguac     2940

ucgugaaauu ccacagcgac gacacaauua caaagaaagg cuuccaccua agauacacgu     3000

ccaccaaauu ccaggacacc cuccacagcc gcaaaugagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  7181
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt11)

<400>  7181
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgccggca cccguugccu ccuugcccuc cuccuacccc      120

aaguccuacu aggcggagca gccggccucg uccccgaacu cggccgccgc aaauucgccg      180

ccgccucauc cggacgcccc uccucacaac ccagcgacga aguacucuca gaauucgaac      240

uucgucuacu cuccauguuc ggccucaaac aacgacccac ucccucccgc gacgcagucg      300

uccccccuua caugcuagac cuuuaccgcc gccacuccgg ccaacccgga ucacccgccc      360

ccgaccaucg ccucgaaaga gccgccuccc gagccaauac cguccgcuca uuccaccacg      420

aagaaucacu cgaagaacua cccgaaacca gcggaaaaac aacacgcaga uucuucuuca      480

accucuccag cauccccacc gaagaauuca ucaccuccgc cgaacuacaa guauucagag      540

aacaaaugca ggacgcccuc ggcaacaacu ccagcuucca ccaccgcauc aacauauacg      600

aaauaaucaa acccgccaca gcuaacucca aguuccccgu cacacgccua cucgacaccc      660

gccuagucaa ccaaaaugcc ucccgcuggg aauccuucga cgucaccccc gccgucaugc      720

gauggaccgc acaaggccac gccaaucacg gcuucgucgu agaaguugca caccuagaag      780

aaaaacaagg cgucuccaaa cgccacgucc gcaucuccag aucccuacac caagacgaac      840

acucaugguc ccaaauccgc ccccuccuag ucaccuucgg acaugacggc aaaggacacc      900

cgcuccacaa acgcgaaaaa cgccaagcca aacacaaaca acgcaaacgc cucaaaucau      960

ccugcaaacg ccacccacuc uacguagacu ucuccgacgu aggauggaac gacuggauag     1020

ucgcaccccc aggcuaccac gcauucuacu gccacggaga augcccauuc ccacuugccg     1080

accaccucaa cuccaccaac cacgcuaucg uacaaacacu cgucaacucc gucaacucaa     1140

aaaucccaaa agcaugcugc guccccacag aacucucagc caucuccaug cucuaccucg     1200

acgaaaacga aaaggucguc cuaaaaaacu accaagacau ggucgucgaa ggcugcggcu     1260

gccgcuaggg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  7182
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt11)

<400>  7182
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaccgggca accgcaugcu cauggucguu cuccugugcc      120

aaguccuacu cggcggcgca agccacgccu cacucauccc cgaaacuggg aaaaaaaaag      180

ucgccgaaau ccaaggccac gccggcggaa gacgcuccgg ccaaucacac gaacuccucc      240

gcgacuucga agccacccua cuacaaaugu ucggccuccg ccgccgccca caacccucaa      300

agagcgccgu cauccccgac uacaugcgcg accuauaccg acuccaaucc ggcgaagaag      360

aagaagaaca aauccacucc accggacucg aauaccccga acgccccgcc ucccgagcaa      420

acaccguacg uucuuuccac cacgaagaac accucgaaaa uauccccggc accuccgaaa      480

acuccgcauu ccgcuuccua uucaaccucu ccuccauccc cgaaaacgaa guaaucucau      540

ccgcagaacu ccgccuauuc cgcgaacaag ucgaccaagg ccccgacugg gaaagaggcu      600

uccaccgaau aaacauuuac gaagucauga aacccccagc cgaagucgua cccggccacc      660

ucaucacacg acuucucgac acacgccuag uccaccauaa cguaacucgc ugggaaaccu      720

ucgacguaag ccccgccguc cuccgaugga cccgugaaaa acagcccaac uacggccucg      780

caauugaagu cacccaccuc caccaaacac gcacacacca aggccaacau guccgcauau      840

cccgaucacu cccacaaggc uccggcaacu gggcccaacu ccguccacuc cucguuaccu      900

ucggccauga cggacgcggu cacgcccuca ccagacgccg cagggccaaa cgauccccca      960

aacaucacuc ccagcgcgcu cguaaaaaaa acaaaaacug ccgccgccau ucccuauacg     1020

uagacuucuc cgacgucggc uggaacgacu ggauagucgc accccccgga uaccaagccu     1080

ucuacugcca cggcgacugc cccuucccac ucgcagacca ccuaaacuca accaaucacg     1140

ccaucguaca aacccucgua aacucaguca acuccuccau ucccaaagcc ugcugcguac     1200

ccaccgaacu auccgccauc uccaugcucu accuagacga auacgacaaa gucguccuca     1260

aaaacuacca agaaaugguc gucgaaggcu gcggcugccg auagggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  7183
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt11)

<400>  7183
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgggcuag gccgacgagc acaauggcua ugcugguggu      120

ggggccuacu augcucaugc ugcggaccac cuccccuacg cccaccccug cccgcagccg      180

cugccgcagc ugccggcggc caacuacuag gcgacggcgg cucacccggc cgaacagaac      240

aacccccucc cucuccccaa uccucauccg gauuccuaua ccgcagacuc aaaacccaag      300

aaaaacgcga aaugcaaaaa gaaauccuau caguacucgg ccugccacau agacccagac      360

cccuccacgg acuccaacaa ccccaaccuc ccgcccugcg ucaacaagaa gaacaacaac      420

aacaacagca acuaccccgc ggcgaacccc cacccggccg ccuaaaauca gcaccccuau      480

uuaugcucga ccuuuacaac gcccucucug ccgacaauga ugaagacggc gccuccgaag      540

gugaacgcca acaauccugg ccccacgaag ccgccucauc aucacaacga cgacaacccc      600

cacccggcgc cgcccaccca cucaaccgaa aaucccuucu cgcccccgga ucugguuccg      660

ggggcgcuuc cccacucacc uccgcacaag acagcgccuu ccuaaacgac gccgacaugg      720

uuaugucauu cguaaaccua gucgaauacg acaaagaauu uucacccaga caaagacacc      780

auaaagaguu caaauucaac cucucccaaa ucccagaagg cgaagucgua acagccgccg      840

aguuccgaau cuacaaagac ugcgucaugg gauccuucaa aaaccaaacc uuccuaauaa      900

gcaucuacca aguacuacaa gaacaccaac accgugacuc cgaccucuuu cuucuagaca      960

cccgaguagu cugggccuca gaagaagguu ggcuugaguu cgacaucacc gccaccagca     1020

accuaugggu agucacaccc caacacaaca ugggacugca acuaucaguc guaacccgcg     1080

acggcguaca cguucacccc cgagcagccg gacucguagg ucgcgacgga cccuacgaca     1140

aacaacccuu cauggucgcc uucuuuaaag ucuccgaagu acacguccga acaacacgau     1200

ccgcaucauc ccgccgccgc cagcaauccc ggaaccgauc aacacaaucc caagacgucg     1260

cccgcgucag cucggcuucg gacuacaacu ccagcgaacu aaaaacagca ugccgcaaac     1320

acgaacuaua cgucuccuuu caagaccucg gauggcaaga cuggaucauc gcacccaaag     1380

gauacgcagc aaacuacugc gacggagaau gcuccuuccc ccuaaaugca cacaugaacg     1440

caaccaacca cgccaucguc caaacccucg uccaccuaau gaaccccgaa uauguaccca     1500

aacccugcug cgccccaacc aaacuaaacg caaucucagu acucuacuuc gacgacaacu     1560

ccaacguaau ccucaagaaa uaccgcaaca ugguuguccg ugccugcgga ugccacuaag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  7184
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt11)

<400>  7184
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacguccgau cacuacgcgc cgcagcccca cacuccuucg      120

uagcacucug ggcaccccua uucuuacucc gcuccgcacu agccgacuuc ucccucgaca      180

acgaagucca cucgagcuuc auccaccgcc gccuacgguc ccaagaaaga cgcgaaaugc      240

aacgcgaaau ccucucaauu cuaggacucc cccaccgccc ccgcccccac cuccaaggca      300

aacacaacuc ugcccccaug uucaugcucg accucuacaa cgccauggca guagaagaag      360

gaggcggacc cggcggccaa ggcuucucau accccuacaa agccguuuuc ucaacccaag      420

gcccgccccu cgcaucccuc caagacucac acuuccuaac cgacgccgac augguaaugu      480

cauucgucaa ccucguagaa caugacaaag aauucuucca cccccgcuau caccaccgcg      540

aauuccgauu cgaccucucg aaaauacccg aaggcgaagc cgugaccgca gccgaauucc      600

gcauauacaa agacuacauc cgcgaacgcu ucgacaacga aacauuccgc aucuccgucu      660

accaagugcu ccaagaacac cucggccgcg aaagcgaccu cuuccuacuu gacucccgca      720

cacuuugggc cucugaagaa gguuggcucg uauucgacau aacagccacc ucaaaccacu      780

ggguagucaa cccccgucac aaccuaggac uccagcuauc aguagaaaca cucgacggcc      840

agagcaucaa ccccaaacuu gcgggacuca ucggccgcca cggaccacaa aacaagcagc      900

ccuucauggu cgccuucuuu aaagccaccg aaguacauuu cagauccaua cgcuccaccg      960

gguccaaaca acgaucacaa aaccgaucca aaaccccaaa aaaccaagaa gcucuacgaa     1020

uggcaaacgu agcugaaaac agcuccucag accaacgcca agccugcaaa aaacacgaac     1080

ucuacgucuc cuuccgagac cucggcuggc aagacuggau caucgcccca gaaggcuacg     1140

cagcauacua cugcgaaggc gaaugcgccu ucccccuuaa cucuuacaug aacgccacca     1200

accacgcaau cguccagacc cucguacacu ucaucaaccc cgaaacuguc cccaaacccu     1260

gcugcgcccc cacccaauua aacgcaaucu ccguccucua cuucgacgac uccucgaacg     1320

ucauacucaa aaaauaccga aacauggucg uccgcgccug cggcugccau uaaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  7185
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt11)

<400>  7185
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagccuccg ccgcccuccu cugccuccuc cucaccgccg      120

ccgccuucuc cccccaaggc cuagcccaac ccgucggcau caacaccucc accaccugcu      180

gcuaccgauu caucaacaaa aaaaucccca aacaacgccu cgaauccuac cgccgcacca      240

ccuccucaca cugcccccgc gaagccguca ucuucaaaac caaacucgac aaagaaaucu      300

gcgccgaccc cacccaaaaa uggguccaag acuucaugaa acaccucgac aaaaaaaccc      360

aaacccccaa acucuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  7186
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt11)

<400>  7186
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cugcucacgc ugaucaucuu auuaccgguc gucaguaaau      120

uuagcuuugu aucacugagc gcaccccaac acuggucaug cccagagggc acuuuggcag      180

ggaacggcaa uucgacgugc guaggaccag ccccauuccu gaucuucagc cacggaaaua      240

gcaucuuccg aaucgacaca gaaggaacga acuaugagca acucguaguc gacgcagggg      300

uaucgguuau cauggacuuc cauuacaacg agaaaagaau auacuggguc gaccuagaac      360

gacagcuccu gcaaagggua uuccugaacg gcucgcggca ggaacgggua ugcaacauag      420

agaaaaacgu cagcggcaug gccauaaacu ggaucaacga agaagugauc ugguccaacc      480

aacaggaagg caucauaacc gucacugaca ugaaaggaaa caacagccac auccuccuau      540

cagcgcuaaa guaccccgcc aaugucgcgg ucgacccagu agaacgguuc auuuucuggu      600

ccuccgaagu agcugggagc cuuuaccgcg cagaccuaga cggcgucgga guaaaagcac      660

uacuugaaac auccgagaaa auaacagcag uaucccuuga cguccuagac aagcgccucu      720

ucuggauaca auacaaucgc gaagggucua acagccucau cugcaguugu gacuaugacg      780

gcgggagcgu acacaucuca aaacacccaa cacaacauaa ucuauucgcg augagccucu      840

ucggugacag aauauucuac ucaaccugga agaugaaaac aauauggaua gccaacaaac      900

acacaggcaa agacaugguc cgcaucaacc uccacagcuc cuucguaccc cucggcgaac      960

uaaaaguagu gcacccccua gcccagccca aagccgaaga ugauacgugg gaacccgaac     1020

aaaagcugug caaacugcgc aaagggaacu gcagcaguac cguuugcggu caagacuuac     1080

agucucaccu cugcaugugc gcugaggggu acgcccuuuc gagagacaga aaauacugcg     1140

aggacgucaa cgaaugcgcc uuuuggaacc acggcugcac acuuggcugc aaaaauacac     1200

cgggaagcua cuacugcaca ugucccguag gauucguccu ucuacccgau ggaaagcgcu     1260

gccaccaacu ggucucgugu ccucgcaacg ucucggaaug cagccaugac ugcguacuaa     1320

ccuccgaagg uccacuaugc uucugcccag aggguucagu ucuagagcgg gacggcaaga     1380

caugcagugg augcucaucc ccagacaacg gcggaugcuc ccaacuaugc gucccacuga     1440

gcccggucuc augggaaugc gacugcuucc cuggguacga ccuccagcuu gaugaaaaau     1500

caugcgcugc cuccgggccc cagcccuucc uacucuucgc caacucgcaa gacauaagac     1560

auaugcacuu cgacggcaca gauuacggga cccugcuguc ccaacagaug ggcaugguau     1620

acgcacucga ccacgaccca guggaaaaua aaaucuauuu cgcccacaca gcccuuaagu     1680

ggaucgaacg cgccaacaug gacggcagcc aaagagaacg gcucauagaa gagggggugg     1740

acgugccaga gggccucgcu gucgacugga uagggcgccg guucuacugg acagaccggg     1800

gcaaaagccu cauaggcaga ucagaccuca acgggaaaag gagcaagauc auaacgaaag     1860

agaauaucuc gcaaccccgc ggaaucgccg uccacccaau ggcaaaaaga cuauucugga     1920

cagauacggg aauaaacccc cggaucgaga gcuccucccu acaagggcuc gggcgguuag     1980

uaaucgccuc cagcgaccua auauggccca gcgggauuac caucgacuuc cuaacagaca     2040

aacucuacug gugcgacgca aaacaauccg ucaucgaaau ggccaaucua gacgguagca     2100

aacgacgccg acucacacaa aacgacguag gccaucccuu ugcggucgcc gucuucgagg     2160

acuacgucug guucucugau ugggccaugc ccucagucau gcgagucaac aagcgcacgg     2220

gaaaggaucg agugaggcuc cagggcucga uguugaaacc aagcagccua guagucgucc     2280

acccacuggc aaaaccaggc gcagacccau gccuauacca gaacgggggc ugugagcaca     2340

ucuguaaaaa gagacuagga accgcauggu gcucaugcag ggaaggguuc augaaagcgu     2400

ccgacggcaa aaccugccuu gccuuagacg gacaccaacu ccuagcagga ggcgaaguug     2460

accuuaaaaa ccaaguaacg ccguuagaua uccucagcaa aacaagggua agcgaggaua     2520

acaucaccga gucacagcac augcucgugg cagaaauuau ggugucagac caagacgacu     2580

gcgcacccgu aggcugcucu auguacgcaa gaugcauauc cgaaggcgaa gacgccacau     2640

gccagugccu gaagggcuuu gccggggacg guaaacugug cuccgacaua gaugagugcg     2700

aaaugggagu acccgucugu ccgcccgcaa gcuccaaaug cauaaacaca gaaggcggau     2760

acgugugccg gugcucagaa ggauaccaag gcgacggaau ccacugccug gacaucgacg     2820

aaugccaguu aggugaacau ucgugcgggg aaaacgccuc cugcacuaac accgaaggag     2880

gcuacacaug caugugcgcc ggacgucuga gcgaacccgg gcuaauaugc cccgacucca     2940

caccaccccc acacuugcgc gaggacgacc accauuacag cguacggaac agcgacagcg     3000

aaugcccccu aucacacgac ggcuacugcu uacacgacgg cgucugcaug uacaucgaag     3060

cccuagacaa auacgcgugc aacugcgugg uagguuacau aggugagcgu ugccaauacc     3120

gagaccuuaa auggugggaa cuacgccacg ccggacacgg ccaacagcag aaggucaucg     3180

ucgucgcagu augcgucgua guccucguca ugcuucuacu ccuaucacua uggggcgcac     3240

acuacuacag aacucaaaaa uuauuaagca agaaccccaa aaauccguac gaggaaucca     3300

gcagagaugu ccgcagccgg agaccggcgg acacggagga cggcaugucc ucgugcccgc     3360

aacccugguu cgucgucauc aaagaacacc aagaccugaa gaacggcggc caacccguag     3420

caggagaaga cggacaagcc gccgacggaa gcaugcaacc gaccucgugg cgacaagaac     3480

cccagcuaug cggcaugggc acugagcagg gcugcuggau uccaguaagu agugacaaag     3540

guagcugccc acaggucaug gagcgauccu uccauaugcc uucuuacgga acacaaacac     3600

uagaaggcgg uguagaaaag ccgcauucuc uccuguccgc aaacccgcuc uggcaacaac     3660

gagcacuaga uccaccccac caaauggaac ucacccaaua aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  7187
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt11)

<400>  7187
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgccggcc gccgcaugga aaugcucugc gccggccgcg      120

uccccgcacu ccuccucugc cucggcuucc accuccuuca agccguccuc uccaccaccg      180

ucauccccuc cugcaucccc ggcgaauccu ccgacaacug caccgcccua guccaaaccg      240

aagacaaccc acgcgucgcc caagucucca ucacaaaaug cuccuccgac augaacggcu      300

acugccucca cggccaaugc aucuaccucg ucgacauguc ccaaaacuac ugccgcugcg      360

aagucggcua caccggcguc cgcugcgaac acuucuuccu caccguccac caaccccucu      420

ccaaagaaua cgucgcccuc accgucaucc ucaucauccu cuuccucauc accgucgucg      480

gcuccaccua cuacuucugc cgcugguaca gaaaccgcaa auccaaagaa cccaaaaaag      540

aauacgaacg cgucaccucc ggcgaccccg aacuccccca agucuaagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  7188
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt11)

<400>  7188
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgaaggcg aaaucaccac cuucaccgcc cucaccgaaa      120

aauucaaccu cccccccggc aacuacaaaa aacccaaacu ccucuacugc uccaacggcg      180

gccacuuccu ccgcauccuc cccgacggca ccgucgacgg cacccgcgac cgcucagacc      240

aacacaucca acuccaacuc uccgccgaau ccgucggcga aguauacaua aaauccaccg      300

aaaccggcca auaccucgcc auggacaccg acggccuccu cuacggcucc caaaccccca      360

acgaagaaug ccucuuccuc gaacgccucg aagaaaacca cuacaacacc uacaucucca      420

aaaaacacgc cgaaaaaaac ugguucguag gccucaaaaa aaacggcucc ugcaaaagag      480

gcccccgcac ccacuacggc caaaaagcca uccucuuccu cccacucccc gucucaucag      540

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  7189
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt11)

<400>  7189
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guggggguag ggggagggga cguggaggac guaacgccga      120

ggccgggagg gugucagaua agcgggagag gggcgagagg gugcaacgga auaccgggag      180

cggcggcgug ggaggcggcg cugccgagga ggaggccgag gaggcacccg agcguaaacc      240

caagaagcag agcagcaggg agcccgagga cgagggggag aaggacggag gagaggccga      300

gugggagcag gcugggggau cgggggaggg ggagagcacu gccgggaggg cgacuagggg      360

gaagagggag ggggagggcg ccggagaggg ugggagggag ggggaggggg agggggacgg      420

cggcgccgag agcggcgccg gcggcgaggg ggagcaggcc gggaccggcg gggacgaugg      480

cagcggggag cauaaccacg uugccggcgc ugccggaaga uggagggagu ggggcguucc      540

caccggggca cuucaaggau ccgaagagac uguauuguaa gaauggaggg uucuuucuaa      600

ggauacaucc ggaugggaga guggaugggg ugagggaaaa gagugacccg cacauaaagc      660

ugcaguugca ggcggaggag agagggguag uaagcauaaa gggggugugc gcaaauaggu      720

aucuggcgau gaaggaggau gggaggcuau uggcgagcaa gugugugacg gacgagugcu      780

uuuucuuuga aaggcuagag agcaauaacu acaacacgua caggagcaga aaguauacga      840

gcugguaugu ggcgcugaag agaacgggac aguacaaguu agggagcaag acagggccag      900

ggcagaaggc aauauuguuc cugccaauga gugcaaagag cuagggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  7190
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt11)

<400>  7190
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uccucaccug gauccucccc acccuccucu      120

accgcuccug cuuccacauc aucugccucg ucggcaccau cucccucgcc ugcaacgaca      180

ugacccccga acaaauggcc acaaacguca acugcuccuc ccccgaacgc cacacccgcu      240

ccuacgacua cauggaaggc ggcgacaucc gcguccgccg acucuucugc cgcacccaau      300

gguaccuacg caucgacaaa cgcggcaaag uaaaaggcac ccaagaaaug aaaaacaacu      360

acaacaucau ggaaauccgc acagucgccg ucggcauagu cgcaaucaaa ggcgucgaau      420

ccgaauucua ccucgccaug aacaaagaag gcaaacucua cgccaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa cucauccucg aaaaccacua caacaccuac gccuccgcca      540

aauggaccca caacggcggc gaaauguucg ucgcccucaa ccaaaaaggc auccccgucc      600

gcggcaaaaa aaccaaaaaa gaacaaaaaa ccgcccacuu ccuccccaug gccaucaccu      660

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  7191
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt11)

<400>  7191
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuccucc ccuccguagu ccucaaacua uuccucgcag      120

ccguccuauc cgcccucguc accggcgaau cacucgaacg ccuccgccgc ggccucgccg      180

caggcacaag caaccccgac ccccccaccg ucuccaccga ccaacuccuc ccccuaggcg      240

gcggccgaga ccgcaaaguc cgcgaccucc aagaagcaga ccucgaccuc cuccgcguca      300

cccucuccuc caaaccccaa gcccuagcaa cccccaacaa agaagaacac ggcaaacgaa      360

aaaaaaaagg caaaggacua ggcaaaaaac gcgaccccug ccuccgcaaa uacaaagacu      420

ucugcaucca cggcgaaugc aaauacguca aagaacuacg cgcccccucc ugcauaugcc      480

accccggcua ccacggcgaa cgaugccacg gccuaucccu ccccguagaa aaccgacuau      540

acaccuacga ccacaccacc auccucgccg ucgucgccgu cguccucuca uccgucugcc      600

uacucguaau cguaggacuc cucauguucc gcuaccaccg ccgaggcggc uacgacgucg      660

aaaacgaaga aaaagucaaa cucggcauga ccaacuccca cuaaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  7192
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt11)

<400>  7192
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ugggucacua aacuacuccc cgcccuccua cugcaacacg      120

uucuccucca ccuauuacug cuccccauug caaucccaua cgccgaaggc cagcgaaaac      180

gccgcaacac gauccacgaa uuuaagaaaa gcgcaaaaac aacccuaauc aaaauagacc      240

cugcacuaaa aauaaaaacc aagaaaguca acacagcaga ccaaugcgcu aacagaugca      300

cccggaacaa aggccugccg uucacaugca aggcauucgu cuucgacaag gcccgcaaac      360

aaugccugug guucccauuc aacucaauga gcucaggcgu caagaaagag uucggacacg      420

aguucgaccu cuacgaaaac aaagacuaca uccgcaacug uaucaucgga aaaggaagau      480

ccuacaaagg cacaguauca aucaccaagu ccggcaucaa augccaaccc uggagcagca      540

ugauccccca cgaacacucc uuccucccca gcucguaccg cggcaaagac cuccaagaaa      600

acuacugccg gaacccccga ggagaagaag gcggucccug gugcuucacc uccaaccccg      660

aaguccgcua cgaagucugc gacauccccc aaugcagcga aguagaaugc augaccugca      720

acggcgaauc cuacagaggc cuaauggauc acaccgaauc cggcaagaua ugccaacgcu      780

gggaccauca aaccccacac cgccacaagu uccuacccga acgcuacccc gacaaaggau      840

ucgacgacaa cuacugccgc aacccugacg ggcaaccacg ccccuggugc uacacccuag      900

acccacacac acgaugggaa uacugcgcca ucaaaaccug cgccgauaac acaaugaacg      960

acacugacgu cccacuagaa accaccgaau gcauacaagg acaaggcgaa gguuacagag     1020

gaaccguaaa cacuauaugg aacggcauac cuugccaacg cugggacucc caauacccac     1080

acgaacacga caugacuccc gaaaacuuca aaugcaaaga ccuccgcgaa aacuacugcc     1140

gcaaucccga uggguccgaa agucccuggu gcuucaccac agacccaaac auccgcgugg     1200

gauacugcuc ccaaauuccc aacugcgaca ugucucacgg ucaagacugc uaccgaggca     1260

acggcaagaa cuacauggga aaccugucac agaccagauc cggucuaacc ugcuccaugu     1320

gggacaaaaa cauggaagac cuccacaggc acauauucug ggaacccgac gccuccaagc     1380

ucaaugaaaa cuacugcagg aaccccgacg acgacgccca cggccccugg uguuacacag     1440

gaaacccccu cauuccuugg gacuacugcc caauaucacg cugcgaaggu gacacuacac     1500

ccacaauagu caaccucgac caccccguca ucucuugcgc caaaacaaaa caacucaggg     1560

uagucaacgg aauccccacc aggacaaaca uaggcuggau ggucucccua cgguaccgca     1620

acaaacacau cugcggaggc ucacugauca aagaauccug gguccucacc gcacgccaau     1680

gcuuccccag cagagaccuc aaagacuacg aagccugguu agguauucac gacguccacg     1740

gcagagggga cgaaaaaugc aagcaagucc ucaacguaag ccagcucguc uacggacccg     1800

aaggaucgga ccucguacuc augaaacugg cccgccccgc aguacucgac gacuucgucu     1860

caacgauuga ccugccaaac uacggaugca cgaucccaga aaagacguca uguagcgucu     1920

acgguugggg cuacacgggc cucaucaacu acgacggccu ccuccgaguc gcacaccuuu     1980

auaucauggg caacgaaaaa ugcagccagc accaccgagg caaagucaca cuuaacgaau     2040

ccgaaaucug ugcaggagcc gagaaaauag gcucaggacc cugcgaaggc gacuacggcg     2100

gaccccuggu cugcgaacaa cacaaaaugc gcaugguccu uggcgucauc guacccggac     2160

gaggcugcgc cauccccaac cgccccggca uauucgucag aguugcauac uaugcaaaau     2220

ggauccauaa aaucauacua acauacaaag ucccccaguc auaaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  7193
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt11)

<400>  7193
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaaagcag cagcaauagg caucgaccua ggaaccaccu      120

acucaugcgu cggagucuuc cagcacggca aaguagaaau aaucgcuaac gaccaaggaa      180

acagaaccac gcccucguac gucgccuuca ccgacaccga acgacugaua ggggacgcag      240

caaagaacca ggucgcacuc aacccacaaa auacagucuu cgacgcaaaa agacucauag      300

gcagaaaauu cggcgacccc guagugcaaa gcgacaugaa acacuggcca uuccaaguga      360

uaaacgacgg ggacaaacca aaaguccaag ucucauacaa aggcgaaaca aaggcauucu      420

acccagaaga aaucuccagc auggucuuaa ccaaaaugaa agaaauagcc gaagcauacc      480

ucgguuaccc aguaacgaac gcagucauua caguacccgc auacuucaac gacagccaac      540

ggcaagccac gaaagacgcg ggagucauag cagggcucaa cguauuaaga auaaucaacg      600

aaccaacagc agcagccauc gcauacggcc uggaucgcac aggcaagggc gaaagaaacg      660

uacugaucuu ugaccuaggc gggggcacgu ucgacguaag cauccugacc auagacgacg      720

ggauuuucga ggucaaagca acagcagggg acacacaccu gggcggggaa gacuucgaca      780

acagacucgu gaaccacuuc guagaagagu ucaaacgcaa acacaagaaa gacaucucgc      840

agaacaaaag agcagugaga agacuacgga ccgcgugcga gcgcgcaaaa cgcacccuaa      900

gcucaagcac gcaggcgagc cuggaaauag acagccucuu cgaaggaauc gacuucuaca      960

caucuauaac aagagcgaga uucgaagaac ugugcuccga ccucuuccgc uccacgcugg     1020

agccagucga aaaagcgcuc cgggaugcga aacuggacaa agcacaaauc caugaccucg     1080

uacuggucgg aggcucgacc cgcauuccaa aagugcaaaa acuccuccag gacuucuuca     1140

acggacgaga ccucaacaaa ucaaucaacc ccgacgaagc agucgcguac ggggccgcug     1200

uccaagccgc aauccugaug ggggacaaaa gcgagaaugu gcaagaccuc cuccuccucg     1260

acguggcccc acucucgcuu ggacucgaga ccgcgggagg cguaaugaca gcacucauaa     1320

aaagaaauuc aacaauccca acaaagcaga cacagaucuu cacaacguau agcgacaauc     1380

aaccgggcgu acucauacaa guauacgagg gcgaacgcgc aaugacgaag gacaacaacc     1440

uucuaggcag auucgagcuc ucaggcauac caccagcccc acgcggggua ccgcaaauag     1500

aagugacauu cgacaucgac gcaaacggaa ucuuaaacgu aacagcgacc gauaaaucaa     1560

ccggaaaggc gaacaaaauc acaaucacaa acgacaaagg acgccuuuca aaagaagaga     1620

ucgagagaau gguacaggag gcagaaaagu acaaagcaga ggacgagguc caacgcgaaa     1680

gaguauccgc caaaaacgcc cuggaaucau acgcauucaa caugaagucc gccgucgaag     1740

acgaaggucu aaagggaaag auauccgaag ccgacaaaaa gaaaguacua gauaaaugcc     1800

aagaagucau cagcuggcuc gacgcaaaca ccuuggccga aaaagacgaa uuugaacaca     1860

aaagaaaaga acuugaacaa guaugcaauc ccauaaucuc aggccuguac caaggcgcag     1920

gcgggccagg gcccgggggc uuuggggcac aaggccccaa aggaggaagc ggaagcgggc     1980

cgacaauaga ggaaguagac uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7194
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt11)

<400>  7194
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgaaagcag cagcaaucgg aaucgaccuc gguaccacau      120

acagcugcgu aggcguauuc caacacggga aaguagaaau cauagcaaac gaccaaggga      180

accggacaac ccccuccuac gucgccuuca ccgacacaga acgacuuauc ggcgacgcag      240

ccaaaaacca ggucgccuua aacccccaaa acaccgucuu cgacgcaaaa agacucaucg      300

gaagaaaauu cggggacccc gugguacaaa gcgacaugaa acacuggccc uuccaaguaa      360

ucaacgacgg agauaagccc aagguccaag uaucguacaa aggcgagacc aaagccuucu      420

acccagaaga aauaucaagc augguguuaa ccaagaugaa ggaaaucgcc gaagccuacc      480

ucggcuaccc agugacaaac gccguaauaa ccgugcccgc guacuucaau gacucccaac      540

gccaagccac gaaagacgcc ggcgucauag ccggacuaaa cguacuacgc auaauaaaug      600

aaccgacagc agccgccauc gcauacggac ucgaccgcac aggcaaaggc gaaagaaacg      660

uauugauauu cgacuuaggc ggaggcaccu ucgacgucuc gauacuaacc auagacgacg      720

gaauauucga ggucaaggcc accgccggag acacacaccu aggcggcgaa gacuucgaua      780

aucgucuagu gaaccacuuc guagaagagu ucaagcgcaa acacaagaaa gacaucuccc      840

aaaacaaacg ugcagugcga aggcuaagaa ccgcaugcga acgcgcaaaa agaacccuca      900

gcuccagcac acaagcgagc cuagaaauag acagucucuu cgaaggcauc gauuucuaca      960

ccucgauaac uagagcgcgc uucgaagaau uaugcagcga cuuauuccga ucgacauuag     1020

aaccuguaga aaaagcgcuc cgggacgcga aacuagacaa agcccaaauc cacgacuugg     1080

uccugguagg gggcucuaca aggauaccga aagugcaaaa gcuauuacaa gacuucuuca     1140

acggacgcga ucucaauaaa uccaucaacc ccgacgaggc aguagcauac ggcgccgcgg     1200

uccaggcagc gauacucaug ggagacaaau cagaaaacgu gcaagaccuc cugcuccuug     1260

acguagcacc acucucgcuc ggacuagaaa cggcgggagg ggucaugacc gcacucauca     1320

agagaaacag uaccauccca accaaacaaa cccaaaucuu caccacauac ucagacaacc     1380

aaccgggagu gcuaauccaa guauacgaag gcgaacgcgc gaugaccaaa gacaauaacc     1440

ugcuaggaag auucgaacua ucaggcauac ccccggcucc acgaggcguc ccccaaaucg     1500

aaguaaccuu cgacauagac gccaacggaa uccucaacgu gacagcgacc gacaaaagca     1560

ccgggaaagc aaacaaaauc acaaucacaa acgacaaagg acgauuaagc aaagaagaga     1620

ucgagcgaau gguccaagaa gccgaaaagu acaaagccga agacgagguc caacgcgaac     1680

gaguaagcgc caaaaacgca uuagaauccu acgcguucaa uaugaaaagc gcaguagaag     1740

acgaaggacu gaaagggaaa auaagcgaag cagacaaaaa gaaaguacuc gacaaaugcc     1800

aagaaguaau cuccuggcua gacgcaaaua cccucgccga aaaagacgag uucgaacaca     1860

aaagaaaaga acuggaacaa gugugcaacc caauuaucuc aggacuauac cagggggcag     1920

gcgggccagg acccggagga uucggcgcgc aaggaccaaa aggaggcagc ggaagcggac     1980

caacaaucga ggaaguagac uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7195
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt11)

<400>  7195
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcgacagcaa agggcauagc aauaggcauc gaccucggca      120

ccacauacuc cugcguaggc gucuuccaac acggcaaagu agaaaucauc gcaaacgacc      180

aaggaaacag gacaacaccc ucauacgucg cauuuaccga caccgaaaga cuuaucggag      240

acgcggccaa aaaccagguc gcaaugaacc cccaaaauac cgucuucgac gcaaagcgac      300

ucauaggacg caaauucaau gaccccgugg uacaggcaga caugaaacua uggccguucc      360

aaguuauaaa cgaaggcgga aagccgaaag uccucguauc cuacaaaggc gaaaacaaag      420

ccuucuaccc cgaggaaauc ucgagcaugg uccuaaccaa acucaaagaa acagccgaag      480

cauuccucgg gcacccaguc accaacgcgg ucauaaccgu accagcauac uucaacgacu      540

cgcaaagaca ggcaaccaaa gacgccggag ucaucgcagg acugaacguc cuccgaauca      600

ucaacgaacc aaccgccgca gccaucgccu acggacuaga caaaggcggg caaggcgaac      660

ggcacguacu uaucuucgac cucgggggcg gaaccuucga cgucuccauc cugaccaucg      720

acgaugggau auucgaaguc aaagccacgg ccggagacac acaccucgga ggcgaagacu      780

ucgacaaccg ccuaguaagu cacuucgucg aagaguucaa acgaaaacac aaaaaggaca      840

ucagccagaa caaacgagca guacgccgcc ucaggacagc augcgaacgc gccaaaagga      900

cacuaagcuc cuccacgcaa gcaaaccucg aaauagacag ccuauacgaa ggaauagacu      960

ucuacacaag caucacaagg gccagauucg aagaacucug cgcagaccua uuccggggca     1020

cacucgaacc agucgaaaaa gcgcugcgag acgccaagau ggacaaagcc aaaauccaug     1080

acauaguccu cgucggaggc uccacccgaa uccccaaagu acaacgacuu cuacaggauu     1140

acuucaacgg aagagaucuc aauaaaucaa ucaaccccga cgaggcgguc gcauacggcg     1200

ccgccgugca ggccgcaaua cucauggggg acaaaagcga gaaaguacaa gaccuguuac     1260

uacuggaugu ggcaccccua agccucgggc uggaaaccgc cggagggguc augaccgccc     1320

ucaucaaacg aaacuccacg auccccacaa aacaaaccca aauauucacc accuacuccg     1380

acaaccagcc aggaguacua auccaaguau acgaaggaga acgcgccaug acaaaagaca     1440

acaaccuacu aggccgguuc gaucuaacag gcauaccacc ggcgccccga gggguacccc     1500

aaaucgaagu aacauucgac aucgacgcca acggcauacu gaacgugacc gcaacggaca     1560

aaucgaccgg gaaagugaac aaaauaacaa ucacaaacga caagggccgc uuaagcaagg     1620

aagaaaucga gcgcaugguc cuagacgcag aaaaauacaa agccgaagac gaaguacaac     1680

gagagaaaau cgccgcgaag aacgcgcugg aaagcuacgc auucaacaug aaaagcguag     1740

uaucagacga gggacuaaaa ggcaaaauaa gcgaaagcga caaaaacaaa auacucgaca     1800

aaugcaacga acuacuaagc uggcuagaag ucaaucaacu cgccgaaaaa gaugaguucg     1860

accacaaacg caaggaacuc gaacaaaugu gcaacccaau aaucaccaaa cuuuaccaag     1920

gaggcugcac aggcccagca ugcggaacag gcuacguacc aggccgaccu gccaccggcc     1980

ccaccauaga agaaguagac uagggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7196
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt11)

<400>  7196
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agugcgcgcg gacccgcaau cggaauagac cucggcacca      120

ccuacucaug cgugggcgua uuccagcacg gaaaagucga aauaaucgca aacgaccaag      180

ggaacagaac cacaccaucc uauguggccu uuacugacac cgaacgccua aucggagacg      240

cugccaagaa ccagguagca augaacccca caaacacaau cuucgacgca aagaggcuaa      300

ucggacgcaa guucgaagac gcaacagucc aaagcgacau gaagcacugg cccuuccgcg      360

uaguauccga aggaggcaaa cccaaggucc aagucgaaua caaaggcgag acaaagaccu      420

uuuucccaga agagaucuca agcaugguac ucaccaaaau gaaagaaaua gcggaggcau      480

aucuuggagg aaagguccac agcgcaguga uaacaguccc cgcauacuuu aacgacagcc      540

aaagacaagc aacaaaagac gcaggaacca uaacaggacu uaacguccuc cgaauaauca      600

augaaccaac agcagcagca aucgcauacg gccuagacaa gaaaggcugc gccggaggcg      660

agaaaaacgu ccuaauauuc gaccuaggcg ggggaacguu cgacgucuca auacucacca      720

uagaagacgg caucuucgag gucaaaagca cggccggaga cacacaccuc ggcggggaag      780

acuucgacaa ccgcauggug agccaucucg ccgaagaguu caaaagaaag cacaagaaag      840

auauaggccc caacaaacgg gcagugagaa ggcucaggac cgcaugcgaa cgggcgaaaa      900

gaacccucag cucaagcaca caagcaagua uugaaaucga cucccuauac gaagggguag      960

acuucuacac cucaaucaca cgggcccgcu uugaggaacu aaacgccgau cuguuccgcg     1020

gaacacuaga accagucgaa aaagcacucc gagacgcaaa auuagacaaa ggccaaauuc     1080

aagaaauagu ccuggucgga gguuccaccc gcaucccaaa aauccaaaaa cuacuacaag     1140

acuucuucaa cgggaaagaa cucaacaaau caauuaaccc cgaugaagca gucgccuacg     1200

gagcagcagu acaagcagcg auacucaucg gggacaaaag cgagaacguc caagaccuac     1260

uacugcuaga cgugacccca cucucacucg ggauagagac agcaggcgga guaaugaccc     1320

cacugauaaa acgaaacaca accauaccca caaaacagac ccagaccuuc acaaccuaca     1380

gcgacaacca gucauccgua cucguccagg uguacgaggg agaacgagca augacgaaag     1440

acaacaaccu auugggcaag uucgaccuaa cgggcauacc gcccgcgccc cgcgguguac     1500

cacaaaucga agucacuuuu gacauagacg ccaacggaau ccuaaacgug accgcggccg     1560

acaaaagcac agggaaggaa aacaagauca caauaacaaa cgacaaaggg agacugagca     1620

aagacgacau ugaccgaaug guccaagaag cagaacgcua caaaucugaa gaugaggcaa     1680

acagagaccg agucgcugca aagaacgcac uggaaucuua caccuacaac aucaagcaga     1740

ccgucgaaga cgaaaaacug cgaggaaaaa uaagcgaaca agacaaaaac aaaauacugg     1800

acaaauguca agaagucaua aacuggcucg accgaaacca aauggccgaa aaagacgaau     1860

acgaacacaa acaaaaagaa cucgaacgag uaugcaaccc cauaaucuca aaauuauacc     1920

aaggaggccc aggaggcggg agcggcggag gaggcuccgg agcgagcgga ggccccacca     1980

ucgaagaagu agauuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7197
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt11)

<400>  7197
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucggucguag gaaucgaucu gggcuuucaa ucaugcuacg      120

uugcaguggc gagagcagga ggaaucgaaa ccauagccaa cgaauacagc gauaggugua      180

cgccggcaug caucagcuuc ggccccaaaa acagaucaau aggagcagcc gccaaaucac      240

aagucaucuc caacgcaaag aacaccguac aaggcuucaa gcgauuccau ggcagagccu      300

uuucggaccc guucgucgaa gcugaaaaau ccaacuuagc guacgacaua guucaacucc      360

caacaggauu aaccggcauc aaagucaccu acauggaaga ggagcgaaac uuuaccaccg      420

aacagguaac cgcgaugcuc cuaagcaagc uaaaggaaac cgcagaaagc guccucaaaa      480

agcccgucgu agauugcgug gucuccgucc caugcuucua cacggacgca gaacgucgca      540

gcguaaugga cgccacacaa auagccggac ucaacugccu acggcugaug aacgaaacga      600

ccgcagucgc acuggccuac gggauauaua agcaagaccu accagcgcug gaagaaaaac      660

cacguaacgu ggucuucguc gacaugggac acuccgccua ccaagucucc gugugcgcgu      720

ucaaccgcgg caaacucaaa guccucgcaa cagcguucga uaccacauug ggcggacgca      780

aguucgauga aguacucgua aaccacuucu gcgaggaguu cggcaaaaag uacaaacucg      840

acaucaaauc gaaaauacga gcacuacucc gccuuagcca agaaugugaa aaacuaaaga      900

aacugauguc agcaaacgcc agcgaccuac cacuaucaau agaaugcuuc augaacgacg      960

uagacguaag cggaacgaug aaucgcggaa aauuccugga aaugugcaac gaccuccucg     1020

cccgaguuga gccgccacua cggagcgugc ucgaacaaac caagcucaag aaagaagaca     1080

uauacgccgu agaaauaguc gggggcgcaa cccgcauccc cgccgugaaa gagaaaaucu     1140

caaaauucuu cgggaaagaa cucagcacca cacucaacgc cgacgaagcg gugacccgag     1200

gcugcgcgcu ccaaugcgca auccuaagcc ccgccuucaa aguacgagag uucuccauaa     1260

ccgacguagu ccccuauccc auaucccuua gguggaauag ccccgcagaa gaaggcagca     1320

gcgacugcga aguauucagc aaaaaccacg ccgcacccuu cucaaaagua cugaccuucu     1380

accgaaaaga accauucaca cucgaggcau acuacagcuc cccacaggac cucccauacc     1440

cagacccggc caucgcccaa uucagcguac aaaaagucac accacaaagc gacgguagcu     1500

cgagcaaagu caagguaaaa guccggguca acguucacgg cauauucuca guaagcagcg     1560

caagccucgu agaaguacac aaauccgagg aaaacgaaga acccauggaa accgaccaaa     1620

acgccaaaga agaagagaaa augcaaguag aucaagagga accacacguc gaggaacaac     1680

agcaacagac ccccgccgaa aacaaagcag aaagcgaaga aauggaaacc agccaagccg     1740

gcuccaaaga uaagaaaaug gaccaaccac cacaagccaa aaaggccaaa gucaaaacau     1800

ccacagucga ucuccccaua gaaaaccaac uacuauggca aaucgaccgc gagaugcuca     1860

acuuauacau agagaaugaa ggcaaaauga uaaugcaaga caaacucgaa aaagagagaa     1920

acgacgccaa aaacgcaguc gaagaauacg ucuacgaaau gcgagacaaa cuaagcggcg     1980

aauacgagaa auucguaucg gaagacgaca gaaacagcuu cacccuaaag cuggaggaca     2040

ccgaaaacug gcuauacgaa gacggagaag accaacccaa acaaguauac guagacaaac     2100

ucgcagaacu caaaaaccua ggccaaccca ucaaaauacg auuccaagaa uccgaggaac     2160

gccccaaauu auucgaagaa cucggcaagc aaauccaaca guacaugaaa auaauaucga     2220

gcuucaaaaa caaagaagac caauacgauc accuggacgc agcagacaug acuaaaguag     2280

aaaaaucaac aaacgaagca auggaaugga ugaacaacaa acucaaccuu caaaacaagc     2340

aaagccuuac cauggaccca guagucaaaa gcaaggaaau cgaagccaag aucaaagagc     2400

ucacaucaac cuguuccccu aucauaucaa aacccaaacc aaaaguagaa ccacccaagg     2460

aagaacagaa aaacgccgaa caaaacggcc ccgucgacgg acaaggcgac aaccccggcc     2520

cccaagccgc cgaacaaggg accgacaccg caguaccaag cgacagcgau aagaaacuuc     2580

ccgaaaugga caucgacuag ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  7198
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt11)

<400>  7198
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucagucgucg gcaucgaucu cggguuccug aacugcuaca      120

uagcagucgc ccggagugga gggaucgaga caauagcaaa cgaauacucg gaccgcugca      180

cacccgcaug cauaagccuc ggcuccagaa cgagagccau cgguaacgcc gcuaagagcc      240

aaaucguaac caacguacgc aacacaaucc acggcuuuaa gaaacuccac ggcagaucgu      300

uugacgaccc uauaguccag acagagcgca uacgacugcc cuacgaacua cagaaaaugc      360

caaacgggag cgcgggcguc aaaguccgau accuagaaga ggagcgccca uucgcaauug      420

aacaaguaac uggaaugcug cuagcaaaau uaaaagaaac gagcgaaaac gcccuaaaga      480

aacccguagc cgauugcguu aucucaauac cgagcuuuuu cacagacgca gagcggcgcu      540

cagucauggc cgcagcccaa gucgccggcc ucaacugccu ccgccucaug aacgaaacaa      600

cugccguugc ccuggccuac ggcaucuaca aacaagaccu accgccccug gacgagaaac      660

cgcgaaacgu cgucuuuauc gacaugggac acuccgcaua ccaaguucua guaugcgccu      720

ucaacaaagg caagcucaaa guacuggcaa ccacauucga ccccuaccuc gguggacgaa      780

acuucgauga agcgcucguc gacuacuucu gcgacgaguu caaaacgaaa uacaaaauca      840

acgucaagga gaacucccgg gcccugcuaa gacucuacca agagugcgaa aaacuaaaga      900

aacuuauguc ggcaaacgcc ucagaccugc cccucaacau agaauguuuc augaaugacc      960

ucgacguaag cuccaaaaug aaccgcgcac aauucgagca acuaugcgcc agccugcuag     1020

ccaggguaga accuccacua aaagcaguca uggagcaggc uaaccuacaa cgcgaggaca     1080

uaagcagcau cgagaucgug ggaggcgcca cacgcauacc cgcagucaaa gaacaaauca     1140

ccaaauuuuu ccuaaaagac aucucaacca cccucaacgc cgacgaagca guagcgcgcg     1200

gcugcgcccu ccaaugcgcg auacucagcc cagccuucaa gguacgcgag uucaguauca     1260

ccgaccucgu ccccuacuca auaacacuaa gauggaaaac cucguucgaa gacggcuccg     1320

gagaaugcga aguauucugc aagaaucacc cggcaccguu cucgaaggua aucaccuucc     1380

acaagaaaga acccuucgaa cuugaagcau ucuacacaaa ucuucacgag guaccauacc     1440

cggacgcacg cauaggcuca uucaccaucc aaaacgucuu cccccaaucc gacggcgacu     1500

caagcaaagu gaaagugaaa guccgcguaa auauccacgg aauauucucc guagcaagcg     1560

caucaguaau cgagaaacaa aaccucgaag gcgaccacag cgacgcacca auggagaccg     1620

aaaccagcuu caagaacgag aacaaggaca auauggacaa aaugcaagua gaccaggaag     1680

aaggacacca gaaaugccac gcagaacaca cccccgagga agaaaucgac cacacaggcg     1740

ccaaaacaaa auccgccgua agcgacaaac aggaucgccu aaaccagacg cucaaaaagg     1800

ggaaagugaa auccauagac cuacccaucc aguccucacu uugccgccag cuaggccagg     1860

accuucugaa cucauacauc gaaaacgagg ggaaaaugau caugcaagac aaacucgaaa     1920

aggaaaggaa ugacgccaaa aacgcagucg aagaauacgu auacgacuuc cgcgaccgac     1980

ugggcacagu auacgaaaaa uucauuacac ccgaagaccu caguaagcua agcgcggucu     2040

uggaggacac cgagaacugg cucuacgaag acggcgagga ccagcccaaa caaguauacg     2100

uggacaaacu acaagaacuc aaaaaguacg gacaaccuau ccaaaugaag uacauggaac     2160

acgaagaacg cccaaaagcu cuaaacgacc uaggcaagaa gauacagcuc guaaugaagg     2220

ucaucgaagc cuaccgcaac aaagacgaaa gauacgacca ccuagaccca accgaaaugg     2280

aaaaaguaga aaaaugcaua agcgaugcaa ugagcuggcu caacucuaag augaaugcac     2340

aaaacaaacu cucccuuacc caagacccag ucguaaaagu cucagaaauu gucgcgaaaa     2400

gcaaagagcu agacaacuuc ugcaauccca ucaucuacaa gcccaaaccc aaagcagaag     2460

uacccgaaga caaacccaaa gccaacuccg aacacaacgg cccgauggac ggccaaagcg     2520

gaaccgaaac aaaguccgac aguaccaaag acagcucgca gcacaccaag uccuccggcg     2580

aaauggaagu cgacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  7199
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt11)

<400>  7199
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuaagcc uggucgcagc aaugcugcua cuacuaagcg      120

cagcaagggc agaggaagaa gacaagaaag aggacgucgg cacaguaguc ggaauagacc      180

uggggacgac cuacagcugu guaggggucu ucaagaacgg cagaguugaa aucaucgcaa      240

acgaccaagg caaccgaaua acaccgagcu acguagcguu cacacccgaa ggcgaaagac      300

ucaucgggga cgcagccaaa aaccaacuaa caagcaaccc ggaaaacaca guguucgacg      360

ccaaaagacu aaucggcaga accuggaacg accccuccgu ccaacaagac auaaaauucc      420

ucccauucaa agugguagaa aagaaaacga aacccuacau acaagucgac auagggggcg      480

ggcagacaaa aacauucgcg ccagaagaaa ucagcgcaau gguccuaacc aaaaugaaag      540

aaacggcaga agcguaccug ggaaagaaag ucacccacgc cgucgucacg guccccgccu      600

acuucaacga cgcgcaacga caagcaacca aagacgcagg cacgaucgcg ggacugaacg      660

uaaugaggau aaucaacgaa ccaacagcag ccgccaucgc auacggacug gacaagcgcg      720

aaggagagaa aaacauacug gucuucgacc ugggcggagg aacauucgac gucucgcuac      780

ugacaauaga caacggcgua uucgaggucg uggcuacgaa cggagacaca caccuaggag      840

gggaagacuu cgaccaacga gucauggaac acuucauaaa acuauacaag aagaaaaccg      900

gaaaagacgu aagaaaagac aacagagccg uacaaaaacu gaggcgcgaa guagaaaaag      960

cgaaacgggc ccugagcucg caacaccaag cgagaauaga aauagagucc uucuacgaag     1020

gagaagacuu cagcgaaaca cuaacgcgcg ccaaauucga agaacucaac auggaccucu     1080

uccgcucaac uaugaagccc guccaaaaag ugcucgaaga cagcgaccug aaaaagagcg     1140

auaucgacga aauaguacug guaggcggaa gcacacggau cccaaaaaua cagcaacucg     1200

ugaaagaguu cuucaacgga aaagaaccau cgcgagggau caacccagau gaagcggucg     1260

cauacggugc agcgguccag gccgggguac uaagcggaga ccaagacaca ggagaucugg     1320

uacuccuuga cgugugccca cuaacccucg ggauagagac cguaggcggc guuaugacaa     1380

aacugauccc ccgcaacacc guaguaccca cgaagaaaag ccaaaucuuc agcacggcaa     1440

gcgacaacca accgaccgua accauaaaag uguaugaggg ggaacgaccc cucacgaaag     1500

acaaccaccu acucggcaca uucgaccuca caggaauacc accagccccg cgcggaguac     1560

cacaaaucga aguaacguuc gaaaucgacg ugaacggaau ccuacgcguc accgccgagg     1620

acaaagggac cggcaacaag aacaaaauca ccaucacgaa cgaccaaaac cgccucacac     1680

cggaggaaau cgaacguaug gucaacgacg cggaaaaguu cgcggaagag gacaagaaac     1740

ucaaagaacg cauagacacg cgaaacgaac uggaaucaua cgcauacuca cugaaaaacc     1800

aaauaggaga caaggaaaag cuaggaggca agcuaucgag cgaggacaaa gaaacaaugg     1860

aaaaggcagu cgaggagaaa auagaauggc uagaauccca ccaagacgca gacauagaag     1920

acuucaaagc gaaaaagaaa gaguuagaag aaaucguuca accaaucauc agcaaacuau     1980

acgguagcgc aggcccaccg ccuacaggcg aggaagauac cgcagaaaaa gacgagcugu     2040

agggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  7200
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt11)

<400>  7200
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagccccac gagagcuagc aguaggaaua gaccucggaa      120

cuacauacuc augcguaggc guauuccaac aaggacgcgu agaaauacuc gcaaacgacc      180

aaggcaaccg caccacgcca agcuacgucg ccuuuaccga caccgagaga cucguaggcg      240

acgcagccaa aucgcaggcc gcccucaauc cccacaacac cgucuucgac gcgaaaagac      300

uaaucggccg aaaauucgcc gauaccacag uccaaagcga caugaaacac uggcccuuuc      360

gcguaguguc agaaggagga aaaccaaaag ucagggucug cuaccgagga gaagacaaaa      420

ccuucuaccc agaagagaua ucgaguaugg uacuauccaa aaugaaggaa accgcagaag      480

ccuaccuagg acaaccagua aagcacgccg ucauaacagu accagcguac uucaacgaca      540

gccaaagaca agccaccaag gacgccgggg ccauagccgg acuaaacguc cuccgcauaa      600

ucaacgaacc gaccgcugcc gcgaucgcau acggccucga ccgcagggga gcuggcgaaa      660

gaaacguccu caucuucgac cucggagggg gaacauucga cgucucagua cuaaguauag      720

acgccggcgu auuugaagua aaagccacag caggcgacac ccaccuagga ggagaagacu      780

ucgacaaccg acucgugaac cacuucaugg aagaguuccg acgcaaacac ggcaaagacc      840

ucuccggcaa caaacgggcc uugagacgac ucagaacagc cugcgaaaga gcaaaaagaa      900

cacucagcuc aagcacacaa gcgacauuag aaauagacuc ccuauucgag ggcguagacu      960

ucuauaccuc gaucacacgc gcaagauucg aggaacugug cucagaccuc uucagaucaa     1020

cccucgaacc ggucgagaaa gcucuaagag acgccaaacu agacaaagca caaauccacg     1080

acgucgucuu aguaggcgga agcacccgaa uaccaaaagu gcaaaaacuc cuacaagacu     1140

ucuucaacgg aaaggagcuc aacaagucaa uaaaccccga cgaagccguc gcauacgggg     1200

ccgcaguaca ggccgcagug cucaugggcg auaaaugcga gaaaguccaa gaccuucuac     1260

uacucgacgu agccccacuu ucccuagggc ucgaaaccgc gggcggggua augaccaccc     1320

ucauccaacg aaacgcaaca auaccaacua aacaaaccca gaccuucaca acauacucag     1380

acaaucaacc gggaguauuc auacaagucu acgaaggcga acgagccaug acaaaagaca     1440

acaaccuucu cggcagguuu gaacucagcg gcauaccccc agccccacgc ggcgucccac     1500

aaauagaagu caccuucgau auagacgcca acggcauacu cagcguaacg gcaaccgacc     1560

gcagcaccgg aaaagcgaac aagauaacca ucacaaacga caaagggcgc cuaagcaaag     1620

aagaggucga gcgcaugguc caugaagcag aacaguauaa agcagaggac gaagcccaac     1680

gagacagagu agcagcgaaa aacagucucg aggcacacgu guuccacguc aaaggcucac     1740

uacaagaaga gagccuacga gacaaaaucc ccgaagaaga caggcggaaa augcaagaua     1800

aaugccgcga aguacucgcu uggcucgagc acaaccaacu ggccgaaaag gaggaauacg     1860

aacaccaaaa acgagaacuc gagcagauau gccgacccau auucucccgc cucuacggcg     1920

gccccggcgu ccccggagga agcagcugcg gcacgcaagc cagacaagga gaccccucaa     1980

ccggacccau aaucgaagaa guggacuaag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  7201
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt11)

<400>  7201
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcccccc gcgaacuagc cguaggcauc gaccucggca      120

caaccuacag cugugucggc guauuccaac aaggcagagu agaaauccua gccaacgacc      180

aaggcaacag aacgacccca ucauacgucg cguucaccga cacagaaagg cuaguaggag      240

acgcagcaaa aucccaagca gcccuaaacc cgcacaacac uguauucgac gccaaacgcc      300

uaaucggacg aaaauucgca gacacaaccg uccaaucaga caugaaacac uggccauucc      360

aagucgucuc cgaaggugga aaacccaaag uacgaguaug cuaccgaggg gaagacaaaa      420

cauucuaccc agaagaaaua agcucaaugg uacuaagcaa aaugaaagaa accgcggaag      480

ccuaccuagg ccaaccagua aaacacgccg uaaucacggu cccgaccuac uucagcaacu      540

cccagagaca ggccaccaaa gacgcaggag caaucgcagg ccuaaaagua cucccaauca      600

uaaacgaagc cacagccgca gcaauagccu acggccugga ccgaagagga gccggcaaac      660

gaaacguacu cauauucgac cuaggaggag gaacauucga cguauccgua cucucgaucg      720

acgccggggu cuucgaagua aaagcuaccg ccggcgacac ccaccuagga ggcgaagacu      780

ucgacaaccg ccuagucaac cacuucaugg aagaauuccg cagaaaacac ggcaaagacc      840

uaagcggaaa caaacgagcc cucagacgac uccgaacagc cugcgaacga gccaaacgca      900

ccccaucaag cagcacccag gccacacuag aaaucgacuc ccuauucgaa ggcguagacu      960

ucuacaaaag caucaccaga gccagauucg aagaacucug cagcgaccua uuccgaagca     1020

cccuagaacc cguggaaaaa gcccuccgcg acgccaaacu agacaaagca caaauccacg     1080

acuucguacu aggcggcggg cuccacagcc acccacaagg cgcagaaguc gccgcaggcc     1140

uacuccaacg acaaggcgca gaacaagaac accagccaua aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  7202
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt11)

<400>  7202
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaaaaggac ccgcaguggg aaucgaccua ggcaccaccu      120

acucaugcgu aggcgucuuc caacacggaa aagucgagau aaucgccaac gaccaaggaa      180

acaggacgac accaucauau guagccuuca ccgacaccga gcgccuaaua ggagacgccg      240

ccaaaaacca ggucgcaaug aacccaacga acaccguauu cgacgccaaa cgacuaaucg      300

gccgccgauu cgacgaugca gucguccaga gcgacaugaa acacuggccc uucaugguag      360

uaaacgacgc cggccgacca aagguacaag ucgaauacaa aggcgaaacc aaauccuucu      420

accccgaaga gguguccagc augguccuca ccaaaaugaa agaaauagca gaagcguacc      480

uggggaaaac agucaccaac gcaguaguca ccguccccgc auacuucaac gacagccaga      540

gacaagcaac aaaagacgca ggcaccaucg ccgggcuaaa cguccuacgc auaaucaacg      600

aacccacagc agcugcaauc gcauacgguc ucgacaagaa aguuggugcc gaacgcaacg      660

uccuaaucuu cgaccucggg ggcggcaccu ucgacguauc aauccucaca auagaagacg      720

gaauauucga agucaaaagc accgcaggcg acacccaccu aggcggcgag gacuucgaca      780

acagaauggu aaaccacuuc aucgcagagu ucaaacggaa acacaagaaa gacaucuccg      840

aaaacaaacg cgcaguacga cgccuacgga cagcaugcga acgcgccaaa cgcacccucu      900

ccuccuccac ccaagcaagc auagaaaucg acagccuaua cgaaggaaua gauuucuaca      960

cauccaucac aagggcgcgc uucgaagaac uaaacgcaga ccucuuccga gguacccucg     1020

acccagucga aaaagcauua agagacgcaa aacuagacaa aagccaaauc cacgacauag     1080

uccugguggg cggaucaacc cguaucccua aaauccaaaa acuacuacag gacuucuuca     1140

acggaaaaga acuaaacaag uccaucaacc cagacgaagc uguggcauac ggcgcggccg     1200

uacaagccgc cauccuaagc ggcgacaaau cggaaaacgu gcaggaccug cuacuccuag     1260

acgucacacc ccucucacua ggcauagaaa ccgcgggcgg cguaaugacc guccuaauaa     1320

aacgaaacac aaccauacca accaaacaaa cgcaaaccuu cacaacauac agcgacaacc     1380

aaccaggggu acucauccaa guauacgaag gcgaacgcgc aaugaccaaa gacaacaacc     1440

uccuaggcaa auucgaacuu acaggaaucc cacccgcacc ccgaggggua ccccaaauag     1500

aaguaacauu ugacauagac gccaacggca uccuaaaugu cagcgccguc gacaaaagca     1560

ccggaaaaga aaacaaaaua acgauaacca acgacaaagg ccgacugagc aaagaagaca     1620

ucgagcgaau gguacaagaa gccgaaaaau acaaagcaga ggaugaaaaa cagcgcgaca     1680

aaguaucaag caaaaacagu cuggaaagcu acgccuucaa caugaaagca acaguggaag     1740

acgaaaaacu ccaaggcaag aucaaugacg aagacaagca gaaaauccuc gacaaaugca     1800

acgaaaucau caacuggcuc gacaagaacc aaacagcaga aaaggaagag uucgaacacc     1860

aacagaaaga acucgaaaaa gucugcaacc ccauaaucac aaaacuguac caauccgcag     1920

gcggaaugcc cggcggcaug cccggaggau ucccaggcgg cggggcacca cccaguggcg     1980

gagccagcuc aggaccgaca aucgaagaag uagacuaagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  7203
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt11)

<400>  7203
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaagcgccu caagagcagc agccgccaga cugguaggag      120

ccgcagcauc aaggggcccg acagcagcca gacaccaaga cucauggaac ggccuaagcc      180

augaagcauu ccgccucgua agccgacgcg acuacgcgag cgaagcaaua aaaggagccg      240

uggucggcau agaccuagga accacgaacu cgugcguggc cguaauggag ggaaaacaag      300

caaaaguacu cgaaaacgcc gaaggggcaa gaacaacgcc cucaguagua gcguucacug      360

cggacggcga aaggcuagua ggcaugccag caaaacgaca agcggugaca aacccaaaca      420

acacguucua cgcaacaaaa cgacucauag gacgacgaua cgacgacccg gaaguacaaa      480

aagacaucaa aaacgucccg uucaaaauag ugcgcgccag uaacggagac gccugggucg      540

aagcccacgg caaacucuac agcccauccc agaucggcgc cuucguccua augaagauga      600

aagagaccgc cgaaaacuac cucggacaca cagcuaaaaa cgcagucauc acugugccag      660

cguauuucaa cgacagccaa aggcaagcca cgaaagacgc cgggcaaaua aguggacuaa      720

acguccuaag ggucaucaac gaaccgacug cagcggcccu ggcauacggc cuagacaaga      780

gcgaagacaa aguaauagcc guauacgacc uaggaggcgg gacauucgac auaagcaucc      840

uagaaauaca gaaaggagua uucgagguaa aaagcacgaa uggggacacg uuccugggug      900

gcgaagacuu cgaccaagca cugcuacgcc acaucgugaa ggaguucaaa cgagaaacag      960

gggucgaccu cacaaaagac aacauggcgc uccaacgagu ccgcgaagca gcggaaaaag     1020

caaaaugcga acuaagcagc agcguacaaa ccgacauaaa ccuacccuac cuaacaaugg     1080

acaguagcgg gccaaaacau cucaacauga aauuaacaag agcucaauuc gaaggcaucg     1140

uaacggaccu aauacgacga accaucgccc cgugccaaaa agccaugcaa gacgcagaag     1200

uaagcaagag cgacauagga gaaguaauac ugguaggcgg caugacaaga augccgaaag     1260

uacaacaaac cguacaagac cuauucggac gagcaccaag caaagccguc aacccggaug     1320

aagcaguggc cauuggcgca gcaauccagg gaggcgugcu agcgggcgau guaacagacg     1380

uacuccuacu agacguaacc ccgcuaagcc uaggaauaga aacccuaggc ggaguauuca     1440

caaagcugau aaacagaaac acaacaaucc caaccaagaa aagccaagua uucagcaccg     1500

cggcagacgg gcaaacccaa guggagauca aagucuguca aggagaacga gagauggccg     1560

gcgauaacaa acugcucggc caauucaccc ugaucggcau accacccgcg ccgagaggag     1620

uaccccaaau cgaggucacg uucgauaucg acgccaacgg cauaguccau guaagcgcca     1680

aagacaaagg aaccggacgc gaacaacaaa uagucaucca aucaagcgga ggccuaagca     1740

aagacgacau cgagaacaug gucaaaaacg cggaaaaaua cgcagaggaa gaccgaagaa     1800

agaaagaaag agucgaagca guaaacaugg ccgaaggaau aauacacgac accgaaacca     1860

aaauggaaga guucaaagac caacuaccag cugacgaaug caacaaacuc aaagaagaaa     1920

uaaguaaaau gcgagagcua cuagcgcgca aagacagcga aacgggagaa aauauacgcc     1980

aggcagcgag cagccugcaa caagcuagcc uaaaacuguu cgaaauggcc uacaagaaaa     2040

uggcauccga aagggaagga agcggaagca gcggcaccgg cgaacagaaa gaagaccaaa     2100

aagaagagaa acaguaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  7204
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt11)

<400>  7204
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagauaaag aagcaggcgg auccgacggg ccacgagaaa      120

ccgccccaac auccgcauac agcucgccag cccgaucacu aggagacacc gguauaacgc      180

cccuuucccc cucccacauc gucaacgaca ccgacucaaa cguauccgaa caacaauccu      240

ucuuaguugu cguggccguc gacuucggaa caacaucauc cggcuaugcc uauucauuca      300

ccaaagaacc ggagugcauc cacgucaugc gucgcuggga aggaggagac cccgggguuu      360

caaaccagaa aacccccacc accauccuuc ucacccccga acggaaauuc cacuccuucg      420

gcuacgccgc ccgggacuuc uaccacgauc uagacccgaa cgaagcaaag caauggcucu      480

accuagaaaa auucaaaaug aaacuucaca ccaccggcga ccucacaaug gauacagacc      540

uuacagccgc aaacggcaag aaagucaaag cgcucgaaau cuucgccuac gcacuccaau      600

acuucaaaga acaagcccuc aaagagcuau ccgaccaagc cggcucagag uucgaaaacu      660

cagacguccg cugggucaua acaguaccug cgauauggaa acaacccgcc aaacaguuua      720

ugagacaagc agccuaccag gcuggacugg cauccccuga aaacucagaa caacucauaa      780

ucgcgcuaga acccgaagcu gcaagcauau acugccgaaa acuccgccuc caccagauga      840

ucgaacugag cuccaaagca gccguaaacg gauacagcgg cuccgacacu gucggcgcag      900

gauucaccca agcuaaagaa cacauccgac gaaaccgcca gucacgcacu uuccuagucg      960

aaaacgucau aggagaaauc uggagcgaac uagaagaagg agacaaauac gucguggucg     1020

auucaggcgg cggcaccguc gaccuaacag uccaccaaau caggcuacca gagggccacc     1080

ucaaagagcu auacaaagca accggcggcc ccuacggauc ccucggugua gacuaugagu     1140

ucgagaaacu gcucuacaaa auauuuggcg aggacuuuau cgagcaauuc aaaaucaaac     1200

gccccgccgc cugggucgac uugaugaucg ccuucgaaag ccgaaaacgc gccgccgccc     1260

ccgacagaac aaacccacua aacaucaccu uacccuucuc guucaucgac uacuacaaga     1320

aauuucgcgg ccacuccguc gagcacgccc uacgaaaaag caacgucgac uucgucaaau     1380

ggucaucgca aggaaugcuc cguauguccc ccgacgccau gaaugcccua uucaaaccca     1440

caauagacuc caucaucgaa caccuccgcg accucuuuca aaagccagaa guaucaaccg     1500

ucaaauuucu cuuccuaguc ggcggcuucg cagaagcacc ccuacuccaa caagccguuc     1560

aagccgcuuu cggcgaccaa ugcagaauca uaaucccaca agacguagga cucaccauuc     1620

ucaaaggcgc cguacuuuuc ggccucgacc cagccgucau uaaagugcga agauccccuc     1680

ugacauacgg cgucggaguc cuaaaccgcu acgucgaagg aaaacaccca cccgaaaaac     1740

uucuagucaa agacggcacc cgauggugca ccgacguauu cgauaaauuc auaucagcag     1800

accaaagcgu cgcccucggc gagcuaguca aaagauccua cacacccgcc aaaccaagcc     1860

aacucgucau cguuaucaac auauacucca gcgaacacga caacguaucg uucauaaccg     1920

accccggggu aaagaaaugc ggcacccucc gccucgaccu aacaggcacc ucaggcaccg     1980

ccgucccagc acgcagagaa auacaaaccc ucaugcaguu cggugacacc gaaaucaaag     2040

ccaccgccau cgacauagca accaguaaau cggucaaagu aggcauagac uuucuaaacu     2100

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  7205
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt11)

<400>  7205
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuagccgucc cagaaauggg cuuacaagga cuuuacaucg      120

gaagcucccc agaacgauca cccguaccca gcccacccgg aucaccccgc acccaggaau      180

caugcggaau cgcgccccug acacccagcc aaagcccaaa acccgaagua cgggccccgc      240

aacaagccuc cuucagcgua gucguggcca uagacuucgg aacgaccagc aguggcuacg      300

cauucucauu cgcaagcgau ccagaggcca uacacaugau gcgaaaaugg gaaggcggcg      360

acccaggagu agcacaccag aaaaccccaa caugccuacu ccuaaccccc gaaggcgccu      420

uccacucauu cggcuacacu gcaagagauu acuaccacga ccucgacccg gaagaagccc      480

gcgacuggcu cuacuucgag aaauucaaga ugaaaaucca cagcgccaca gaccuaacac      540

ugaaaaccca acucgaggcg gugaacggca agacaaugcc agcacucgaa guauucgcac      600

acgcccuccg auucuuccgc gaacacgcac uacaagaacu acgcgaacaa agccccaguc      660

ugcccgagaa ggacaccguc cggugggugu uaaccguacc cgcaaucugg aaacaaccag      720

caaaacaauu caugcgcgaa gccgccuacu uagccggacu uguaagcaga gagaacgcag      780

aacaacuccu cauagcccug gaacccgaag ccgccuccgu auacugccga aaacuacgac      840

uacaccaacu acuagaccug ucgggccgcg cccccggcgg cggccgccua ggcgaaagac      900

gaagcauaga cuccuccuuc cgccaagccc gagaacaacu aagaagaucc agacacucac      960

gaaccuuccu aguagaaucc ggagucggag aacuaugggc cgaaaugcaa gccggcgacc     1020

gcuacguagu cgccgacugc ggagggggca cugucgaccu uaccguacac caacuagaac     1080

aaccacaugg cacccuaaaa gaacuauaca aagccucggg aggucccuac ggggcugucg     1140

gcguagaccu cgcauucgag caacuccuau gccgcaucuu cggagaagac uucaucgcaa     1200

cauucaaacg ccaaaggccc gccgcauggg ucgaccucac uaucgccuuc gaagcacgaa     1260

aacgaacagc aggaccccau cgcgcaggcg cccucaacau cucacuaccc uuuuccuuca     1320

uagacuuuua cagaaaacaa agagggcaca acguagagac agcacucaga cgauccagcg     1380

ugaacuucgu aaaaugguca ucccaaggga ugcugcgaau gucaugcgaa gcaaugaacg     1440

agcuauucca accaacagua ucaggcauaa uccaacacau cgaagcacug cucgcccgac     1500

cagaaguaca aggcguaaag cuccucuucc uagucggcgg auucgccgaa agcgcagucc     1560

uccaacaugc cguccaagcc gcccugggcg cacgcggacu acgagucguc guaccacacg     1620

acgucggacu cacgauacuc aaaggagccg uacuauucgg acaagcccca ggaguagucc     1680

gcguccgccg uucgccgcuc accuacggcg ucggcguccu caacagauuc guaccaggac     1740

gccauccccc agaaaaacug cugguccgcg acggccgcag augguguaca gacgucuucg     1800

aacgcuucgu agcagccgag caauccgucg cgcuaggaga ggaaguccgc cguucauacu     1860

gucccgccag acccggccaa cgaagaguac ucaucaaccu auacugcugc gcagcagaag     1920

acgcacgcuu cauaacugac ccaggcgucc ggaaaugcgg cgcccucuca cuagaacucg     1980

aacccgccga cugcggacag gacaccgcag gagccccacc cggacgacgc gaaauucggg     2040

ccgccaugca auucggcgac accgaaauca aggugacagc cguggacguc agcacgaacc     2100

gcagcguuag agcaagcaua gacuuccucu caaacuaagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  7206
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt11)

<400>  7206
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgcgaaa ugaccauccu cggcucagcc guccuuaccc      120

uacuacuagc gggauaccua gcccaacaau accuuccacu acccaccccc aaagucauag      180

guauagaccu cggaaccacc uacugcuccg ucggcgucuu cuuucccgga accggaaaag      240

ucaaagucau cccagacgaa aacggacaca ucucuauccc cucgaugguc agcuucacag      300

acaacgacgu auacgucggc uacgaauccg ucgagcuagc cgacagcaac ccacaaaaca      360

caaucuacga cgccaaacgc uucaucggca aaaucuucac cgccgaagaa cucgaagccg      420

aaaucggacg cuaccccuuc aaaguacuca acaaaaacgg cauggucgag uucucaguaa      480

ccagcaacga aaccauaacc guaucccccg aauacgucgg cucacgcuua cuacuaaaac      540

ucaaagagau ggcagaggcu uaccucggca ugccggucgc caacgcuguc auaagcgucc      600

ccgcggaguu cgaccucaaa caacgcaacu ccaccauuga agcagcgaac cuggcaggac      660

uaaaaauccu ccggguaaua aacgaaccca cagcagcagc cauggccuac ggacuccaua      720

aagccgacgu cuuucacguu cuagucaucg acuuaggcgg aggcacccuc gacgucuccc      780

uccucaacaa acagggcgga auguuccuaa cacgcgccau gucaggcaac aacaaacucg      840

gcggccagga cuucaaccaa cgccuacuuc aauaccucua caaacagauc uaccagaccu      900

auggauucgu acccucucgg aaagaagaaa uccaccgccu ccgccaagcc guagaaaugg      960

uuaaacucaa ccucacccua caccagucag cgcaacuauc cguccuccuc acggucgaag     1020

aacaagaccg caaagaaccc cacucaucag acaccgaacu ccccaaagac aaacucuccu     1080

cagccgacga ccaccgcgug aacucaggcu ucggccgcgg ccuauccgac aagaaauccg     1140

gcgaaucuca aguacucuuc gagacagaaa uaagccgcaa acucuucgac acccuaaacg     1200

aagaccucuu ccagaaaaua cucguaccca uccaacaagu ccuaaaagaa ggccaccuug     1260

agaaaaccga aaucgacgaa gucguucucg ucggcggcuc cacccgcauc ccccguauuc     1320

gacaagucau acaagaauuu uucggaaaag aucccaacac uagcgucgac cccgaccuug     1380

caguagucac agggguagcc auccaagccg gaauagacgg cggauccugg ccccuucaag     1440

ucuccgcacu cgaaaucccc aacaaacacc uucagaaaac caacuucaac uagggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  7207
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt11)

<400>  7207
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgccaucg gaguccaccu cggcugcaca uccgccugcg      120

uggccgucua caaagacgga cgcgcaggcg uagucgccaa cgacgccgga gaccgcguca      180

cccccgccgu agucgccuac agcgaaaacg aggaaauagu cggacucgcc gccaaacaau      240

cccgaauacg caacauaucc aacacaguaa ugaaagucaa acaaauccuc ggacgaagca      300

gcagcgaccc acaagcccaa aaauacaucg ccgaauccaa augccuuguc aucgagaaaa      360

acggaaaacu acgauacgaa aucgacacag gggaagaaac caaguucguc aacccagagg      420

acgucgcacg ccucaucuuc agcaaaauga aggagaccgc acauagcgua cuaggguccg      480

acgccaacga cgucguaaua accgucccau uugacuucgg cgaaaaacaa aagaacgcac      540

uaggcgaagc cgcccgcgcc gcuggcuuca acguccugcg acuaauacac gaaccaucag      600

cagcacuacu agccuacggc aucggacaag acucaccaac aggcaaauca aacauacucg      660

uauucaaacu cggaggcacu agccuaucac uauccguaau ggaggugaac agcggcaucu      720

accgcguacu caguaccaac acagaugaca acauaggcgg cgcccacuuc acagaaaccc      780

uagcgcaaua ccuagcgucg gaauuucaac gcagcuucaa acacgacguc agaggaaacg      840

cccgcgcgau gaugaaacua accaacagcg cggaagucgc aaaacacucc cucucaaccc      900

ucggcuccgc caacugcuuc cucgacucac ucuacgaagg ccaggacuuc gacugcaacg      960

ucucaagagc ccgcuucgaa cuccugugcu ccccacuauu uaacaaaugu aucgaagcaa     1020

uacgcggacu ccuagaccaa aacggcuuca cagccgacga caucaacaaa gucguccucu     1080

gcggcggcag cucgcgcauc cccaaacucc aacaacuaau caaagaccuc uucccagccg     1140

ucgaacuacu caacucgauc ccacccgaug aaguuauucc cauuggagcc gccaucgaag     1200

ccggcauccu aaucggcaaa gaaaaccuac ugguagaaga cucacuaaug aucgaaugcu     1260

cagcccgcga cauccucguc aaaggagucg acgaaagcgg agccucccga uucaccguac     1320

uauucccuuc cggaacgccg cucccagccc gccgacaaca cacccuccaa gcccccggcu     1380

ccaucuccuc cgucugccuc gaacucuacg aaagugaugg caaaaacuca gccaaagaag     1440

aaaccaaauu cgcgcaagua guacuacaag accucgacaa gaaagaaaac ggacuacgcg     1500

acauccuagc cguacucacc augaaacgcg acggaucacu ccacguaacc ugcacagacc     1560

aagaaacagg caaaugcgaa gcuaucucca uagaaaucgc cucaugagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  7208
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt11)

<400>  7208
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccgugguag gacucgacgu cgggagccaa agcugcuaca      120

uagcgguagc cagggcaggc gggauagaga cgaucgccaa cgaguucucc gaucgcugca      180

cacccagcgu caucagcuuu gguucuaaaa acaggacuau aggaguggcc gccaaaaacc      240

aacaaauaac ccaugcaaac aacaccguca gcaacuucaa acgauuccac ggacgugccu      300

ucaacgaccc cuuuauacaa aaagaaaaag aaaaccuauc cuacgaccua gucccccuca      360

agaauggagg cgugggcauc aaaguuaugu auaugggaga agaacaccug uucucaguag      420

aacagauaac cgccaugcua cuaacaaaac ugaaggaaac cgcagagaac agucugaaga      480

aaccugucac cgacugcgua aucuccguac ccuccuucuu caccgacgca gaacggagau      540

ccguacuaga cgcagcccaa auaguaggcc uaaacugccu ccgccugaug aacgauauga      600

cggccguagc acucaacuau gggauuuaca aacaagaccu cccaagccuc gacgaaaaac      660

cccgcauagu agucuucguc gacaugggac acucagcauu ccagguaagc gcaugcgccu      720

ucaacaaagg aaaacucaaa guccuaggca cggcuuucga ccccuuccua ggcgggaaaa      780

auuucgacga gaaacucguc gaacacuucu gcgccgaguu caaaaccaaa uacaaacucg      840

acgcaaagag caaaauccga gcccuccuac gccuauacca ggaaugcgaa aagcuaaaga      900

aacugauguc cuccaacucc accgaccuac cccuaaacau cgaauguuuc augaacgaca      960

aggacgucag cggaaagaug aacagauccc aguucgagga gcucugcgcc gagcuacucc     1020

aaaagauaga agucccccuc uacagccuuc ucgaacagac ccaccucaaa guagaagacg     1080

uuucagccgu cgaaaucguc ggcggagcaa cacgcauccc cgcggucaaa gaacgcaucg     1140

ccaaauucuu cgggaaggac auauccacca cccuaaacgc agacgaagca guggcacgcg     1200

ggugugcccu ccagugcgcc auccuaagcc ccgcauucaa aguacgagag uucucaguaa     1260

ccgaugccgu cccguuccca auaagccuga uauggaacca cgacagcgag gacaccgaag     1320

guguccacga agucuucagu cgaaaccacg cggccccauu cucaaaagua uuaacguucc     1380

uccgacgcgg acccuucgaa cucgaagcau ucuacagcga cccgcaaggc guaccguacc     1440

cugaggcaaa gauuggcagg uucguagucc agaacgucuc cgcacagaaa gauggcgaga     1500

aaagccgcgu aaaggucaaa guccgaguca acacacacgg aaucuucacc auuuccaccg     1560

ccucaauggu agaaaaaguc cccacagaag aaaacgagau gagcucugaa gccgacaugg     1620

agugccucaa ccaacgccca cccgaaaacc ccgacaccga caagaacguc caacaagaca     1680

acagcgaagc aggaacccag ccccaagucc aaaccgacgc acaacagacc agccagagcc     1740

cacccucccc cgagcucaca ucagaagaaa auaagauccc agacgcagac aaggccaacg     1800

aaaagaaagu cgaccagccc ccggaggcca agaaacccaa aaucaaagug gucaacguag     1860

aacuccccau cgaagcaaac cuggucuggc agcuagguaa agacuuacua aacauguaca     1920

ucgaaaccga aggcaaaaug auaaugcaag auaaacucga aaaagaacgc aacgacgcca     1980

aaaacgcagu cgaagaauac guauacgagu uccgggacaa acuaugcggc ccauacgaaa     2040

aauucaucug ugaacaagac caccaaaacu uucuacgucu auuaaccgaa accgaagacu     2100

ggcucuacga agaaggcgaa gaccaagcaa aacaggcuua cgucgauaaa cuggaagaac     2160

uaaugaaaau cggaacgccg gucaaagugc gguuccaaga agcagaagaa cgucccaaaa     2220

uguucgagga acucggacaa agacuccaac acuacgcgaa aaucgccgcc gacuuccgca     2280

acaaagacga gaaguacaac cacaucgacg aaucagaaau gaagaaagua gaaaagucgg     2340

ucaacgaagu aauggaaugg augaacaacg uaaugaacgc ccaagccaaa aagucccucg     2400

accaagaccc agucguccga gcacaagaaa ucaaaaccaa aauuaaggaa cugaacaaua     2460

ccugcgagcc cgucguaacg caaccgaaac caaaaauaga aucccccaaa cucgaacgaa     2520

cccccaacgg gccgaacauc gacaagaaag aagaagaccu cgaggacaaa aacaacuucg     2580

gagcagaacc accacaccaa aacggcgaau gcuacccaaa cgagaaaaac agcgucaaca     2640

uggaccucga uuaaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  7209
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt11)

<400>  7209
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagacaagg ucaggcggca acgaccacgg aggcgcguau      120

guugggcgcu agucgcaguc cuacuugcgg accuacuggc acuaagcgac acgcuggcag      180

uuauguccgu agaccucgga agcgaaucga ugaaagucgc gaucgucaaa cccggcgucc      240

caauggaaau aguccuaaac aaggaaagcc gcaggaagac cccggugaua gugacacuca      300

aagagaacga acgcuucuuc ggagacucgg ccgcgagcau ggccauaaag aaccccaaag      360

caacgcuaag auacuuccaa caccuccucg ggaaacaagc agacaaccca cacguggcac      420

ucuaccaggc aagguuccca gaacacgagc ugacauucga cccgcaacgc caaacgguac      480

acuuccaaau aucaucacaa cugcaauuuu cacccgaaga aguccuagga auggugcuca      540

acuacuccag aucauuagcc gaagauuucg ccgaacaacc aauaaaagac gcagucauaa      600

caguacccgu cuucuucaac caggcagaac gccgagcagu ccuacaagcc gcgaggaugg      660

caggccuuaa aguccuccaa cugaucaacg acaacaccgc aacagcacug agcuauggcg      720

ucuucagacg gaaggacaua aacaccaccg cacagaauau aauguuuuac gacaugggaa      780

gcggauccac agugugcacc auaguaaccu accaaauggu gaaaacgaag gaggccggca      840

ugcaaccuca gcuccaaauc cgagggguag gauucgaccg gacacucggc gggcuagaaa      900

uggaacuacg gcuaagagaa agauuagcgg gacuguucaa cgaacagcga aaaggacaac      960

gagcgaaaga cgucagggaa aacccccgcg cgauggcaaa gcuccuucga gaggcaaacc     1020

gccugaaaac agugcuguca gcgaacgcgg accacauggc ucaaauagaa ggacucaugg     1080

acgacgucga cuucaaagca aagguaacac gagucgaauu ugaagaacua ugcgcggauc     1140

uauucgaaag agugcccgga cccguacagc aagcacugca guccgccgaa augucccuag     1200

augaaauaga acaaguuauc cuagucggcg gcgccaccag aguaccacga gugcaggaag     1260

uacuacucaa agccguaggc aaggaggaac uagggaaaaa cauaaacgcc gacgaagcag     1320

cagcgauggg ggcaguuuac caagccgccg cacucagcaa ggcauucaaa gucaaacccu     1380

ucgucguacg agacgccguc guauacccga uacugguaga guucacacgc gaaguggagg     1440

aggaaccagg aauacauagc cugaaacaca acaagcgagu ucucuucagc cgaaugggcc     1500

ccuaccccca aagaaaagug aucaccuuca accgguacag ccacgacuuc aacuuccaca     1560

uaaacuacgg cgaccucgga uucuuggggc ccgaagaccu caggguauuc gggagccaaa     1620

accugacaac agucaaacuc aaaggcguag gcgacagcuu caaaaaguac ccagauuacg     1680

aaaguaaagg cauaaaagca cacuucaauc uugacgaaag cggagugcuc ucgcucgacc     1740

gcguggagag cgucuuugaa acccuaguag aggacagcgc cgaagaagaa agcacgcuaa     1800

caaagcuggg aaacaccaua uccucacuau ucggaggggg aacgacacca gacgcaaaag     1860

agaacggaac cgacaccguc caagaagagg aagagagccc agcugaaggg uccaaagacg     1920

agccaggaga acaaguugaa cuuaaagaag aagcggaggc cccuguugag gacggaagcc     1980

aaccgccccc acccgaaccc aaaggcgacg ccacaccaga aggcgaaaag gcaaccgaga     2040

aggaaaacgg agacaaaucc gaagcccaaa aaccaagcga aaaagcagag gccggcccag     2100

aaggggucgc gcccgcaccg gaaggggaga agaagcaaaa acccgcacga aaacgcagaa     2160

ugguggaaga aaucggagua gagcuagucg uacuagaccu accagaucug ccggaagaca     2220

aacuagcaca aucaguucag aaacuucaag acuugacccu acgggaccug gaaaaacaag     2280

aaagagaaaa agcagccaac agucucgaag ccuucaucuu cgagacacaa gacaaacugu     2340

accaacccga guaccaggaa guaagcacag aagaacagag agaagaaauc aguggaaaac     2400

ugagcgcugc gucaacaugg cuagaagacg aagggguagg ugcaacaacc gucaugcuua     2460

aagaaaagcu cgccgaacug cgcaaacucu gccaagggcu auucuuccga guagaagaga     2520

ggaagaaaug gccagaaagg cuauccgcac uagacaaccu acugaaccac ucgagcaugu     2580

uccuaaaggg agcaagacuc auaccagaga uggaccaaau auucaccgag guggaaauga     2640

caacacucga aaagguaaua aacgaaacgu gggccuggaa aaacgccaca cuagcagagc     2700

aagccaaacu gccagcaaca gagaaaccag uacugcuauc aaaggacauc gaagcaaaaa     2760

ugauggcacu ggacagagag gugcaauacc uccucaacaa agcaaaauuc acaaaaccca     2820

gaccacgacc aaaagauaag aacggaacac gcgcagagcc accccuaaau gcuucggcga     2880

gcgaucaagg ggagaaagua auacccccag ccgggcaaac cgaggacgcc gagccgaucu     2940

ccgaacccga aaaggucgaa acaggcucag aacccgggga uacagaacca cuugaacucg     3000

gcggacccgg agccgagcca gaacagaagg aacaaaguac agggcaaaaa cgcccccuga     3060

aaaacgacga acuauaggga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  7210
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt11)

<400>  7210
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaagaaa cccaaacaca agaucaacca auggaagaag      120

aagaagugga aaccuucgcg uuccaggcgg aaauagccca acuaaugucc cucaucauca      180

acaccuucua cagcaacaag gaaaucuucc ugcgagaacu uaucagcaac agcagcgacg      240

cccucgauaa gaucagauac gaaagccuaa cugacccaag caaacuagau agcgggaaag      300

aacuccacau caaccuaaua cccaacaaac aagaccggac ccucacaaua guagacaccg      360

gaaucggaau gacaaaggcg gaccuuauaa acaaucuggg aaccaucgcg aaaagcggga      420

caaaggcauu cauggaagcg cuccaggcag gggcagacau aucaaugauc ggccaauucg      480

gagucggcuu cuacucagcg uaccuaguag ccgagaaagu aaccgucaua accaaacaca      540

acgacgauga gcaguacgcg ugggagagca gcgcgggagg aucguucaca gugagaaccg      600

acacagggga accgauggga cgcggaacga aaguaauacu acaccucaaa gaagaccaga      660

ccgaauaccu cgaagaaagg cgaauaaaag aaauagugaa gaaacacucc caguucaucg      720

gauacccgau aacacuauuc guggagaaag agcgcgacaa agaggucagc gacgacgaag      780

cagaagaaaa agaagacaaa gaagaggaaa aggaaaaaga agaaaaagaa agcgaagaca      840

aaccagagau cgaagacgug ggaagcgacg aagaagaaga aaagaaagau ggagacaaga      900

agaaaaagaa gaaaaucaaa gagaaauaca uagaccaaga agaacuaaac aaaacgaaac      960

caaucuggac ccggaaccca gacgacauaa ccaaugaaga auacggcgag uucuacaaau     1020

cacucacaaa cgacugggaa gaccaccucg ccguaaaaca cuucucggua gagggacaac     1080

uagaguuccg agcgcuccug uucgugccaa ggcgagcccc auuugaccug uucgagaaua     1140

gaaagaagaa aaacaacaua aaacucuacg uccgccgggu cuucaucaug gacaacugug     1200

aagaacuaau uccggaauac cugaacuuca uccgcggcgu aguggacagc gaagaccugc     1260

cgcucaacau cucgagagaa auguuacaac aaagcaaaau ccucaaagua auaaggaaga     1320

accucgugaa gaaaugccug gaauuauuca cagaacuagc cgaagacaaa gaaaacuaca     1380

agaaauucua cgagcaauuc agcaaaaaca uaaaacuggg cauccacgaa gacagccaaa     1440

accgcaagaa acuauccgag cuccuacgcu acuacaccuc cgcauccggg gaugagaugg     1500

ugucacuaaa agacuacugc accagaauga aagaaaacca aaaacacauc uacuacauca     1560

cgggcgaaac aaaagaccaa guagcgaacu cagccuucgu cgagcgccua cgaaaacacg     1620

ggcuagaagu cauauacaug aucgaaccaa uagacgaaua cugcguccaa caacucaaag     1680

aguucgaagg aaaaacccuc gucagcguua ccaaagaagg cuuggagcuc cccgaagacg     1740

aagaagagaa aaagaaacaa gaagaaaaga aaaccaaauu cgaaaaccug ugcaaaauca     1800

ugaaggacau acuggaaaag aaaguagaga aggucguagu aucaaacagg cucgugacca     1860

gccccugcug cauagucaca ucuaccuacg gauggacggc caacauggaa agaauaauga     1920

aggcccaagc acuccgcgac aacucgacaa ugggcuacau ggcggccaag aaacaccucg     1980

agaucaaccc cgaccacucc aucaucgaaa cgcucaggca gaaagccgaa gcagacaaaa     2040

acgauaaauc cgugaaggac cucguaauac uccuauauga aacggcccuu cuaagcagcg     2100

gguucagccu cgaagacccg caaacgcacg cgaacaggau cuaccgaaug aucaaacucg     2160

gccuugggau cgacgaagac gacccaacag cagacgacac gagcgcggcc guaacggaag     2220

aaaugccacc acuagaaggc gacgacgaca cgagcaggau ggaggaagug gacuagggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  7211
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt11)

<400>  7211
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucaa aacuggacuc gggcaagggc cugcacauaa      120

accugguccc gaacaagcaa aaccaaacac ucacgaucgu ggacacgcgc auaggcauga      180

ccaagaccga ccucauaaac aaccucggga ccgugaccaa gagcgggacc aaggccuuca      240

uggaggcccu gcaagcggac gcggacauaa gcaugaucgg acacuucggc gugggcuucu      300

acucggccua ccucguggcc aagaaaguga ccgugaucuc aaaacacaac aacgacgagc      360

aauacaccug ggaaucgagc gcgggcggga gcuucaccgu gcgcacggac gaguaaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  7212
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt11)

<400>  7212
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccgaagaag ugcaccacgg ggaagaggaa gucgaaaccu      120

ucgccuucca ggccgagaua gcccaacuca ugagcuuaau cauaaacacc uucuacucca      180

acaaagaaau cuuccucaga gaguugauau caaacgcaag cgacgcccug gacaagauaa      240

gauacgaaag ccuaacagac ccaucaaaac uggacucagg aaaggaguua aaaauagaca      300

ucaucccaaa cccacaagaa cgcacgcuca cccucgugga caccggaaua ggaaugacaa      360

aagccgaccu cauaaacaau cucggcacga uagccaagag cgggacaaaa gccuucaugg      420

aggcccuaca agcaggagcc gacauaagca ugaucggaca auucggcgua ggcuucuaca      480

gcgcauaccu cgucgccgaa aaggugguag uaaucacaaa acacaacgac gacgaacaau      540

acgccuggga aagcagcgcc ggcgggagcu ucacagucag agcagaccac ggcgaaccua      600

uaggacgcgg gacuaaagua auccuccacc uaaaggaaga ccaaaccgaa uacuuagaag      660

agcgcagggu caaggaaguc gucaaaaaac acagccaguu caucggcuac cccauaaccc      720

ucuaccugga aaaagagagg gaaaaggaaa uaagugacga cgaggccgag gaagaaaaag      780

gagaaaaaga agaagaagac aaagacgacg aagaaaagcc caagaucgaa gacguaggaa      840

gcgacgaaga agacgacuca ggaaaggaca agaaaaaaaa aacgaaaaaa aucaaagaga      900

aauacaucga ccaagaagag cugaacaaaa caaaaccaau cuggaccagg aaccccgaug      960

acaucacaca agaagaauac ggggaauucu acaaaucgcu aacaaacgac ugggaggacc     1020

accucgcggu aaagcacuuc agcguggaag gacaacucga auucagagca cuacuauuca     1080

ucccaaggag agcgccauuc gaccuguucg aaaacaagaa aaaaaaaaac aacauaaagc     1140

uauacguccg acgagucuuc auaauggacu caugcgacga acugauccca gaauaccuaa     1200

acuucauccg gggcguagua gacuccgaag accucccacu caacaucagc cgagaaaugc     1260

uacaacagag caagauacug aaagugauca gaaaaaacau cguaaaaaag ugccuagaac     1320

uauucagcga auuagcagag gauaaagaaa acuacaagaa auucuacgaa gccuucagca     1380

agaaccuaaa acugggcaua cacgaagaca gcaccaaucg aaggcgccua agcgaacuac     1440

uaagauacca cacaagucag agcggcgacg agaugacgag ccuauccgaa uacguuagcc     1500

ggaugaaaga aacgcaaaag ucaauauacu acaucaccgg agagagcaag gaacaaguag     1560

cgaacucggc auucgucgaa cgcgugcgaa agcgcggauu cgaagucgua uacaugacgg     1620

agcccaucga cgaguacugu guacaacagc ucaaagaauu cgacggcaaa agccuagucu     1680

caguaaccaa agaaggacua gaauugcccg aagacgaaga agagaagaaa aaaauggaag     1740

aaucaaaagc caaauucgag aacuugugca agcugaugaa agagauccua gacaaaaagg     1800

uagaaaaggu cacgaucuca aaccggcugg ugagcucgcc cugcugcauc gucacgagca     1860

cauacggcug gacagcaaac auggaacgaa uaaugaaagc acaagcccuc agagacaacu     1920

caaccauggg guacaugaug gccaagaaac accucgaaau aaaccccgac cacccuauag     1980

uagaaacgcu caggcaaaag gccgaagcag acaaaaacga caaagccgua aaagaccucg     2040

ugguccugcu cuucgaaaca gcccuacucu caagcggauu uucacuggag gacccacaaa     2100

cccacagcaa cagaaucuac cgaaugauua agcucggacu ggguauugac gaggacgaag     2160

uagccgcgga agagcccaac gcggcagucc ccgacgaaau cccgccccug gaaggggacg     2220

aggacgcauc aagaauggaa gaggucgacu agggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  7213
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt11)

<400>  7213
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agagcccuau gggugcucgg gcucugcugc guacuacuca      120

cguucggauc aguccgagca gacgacgagg ucgacgucga cggaacgguc gaagaagacc      180

uaggaaaaag ccgcgaaggc agccggacag acgacgaggu cguccagcga gaggaagagg      240

caauacaacu cgacggucua aacgccagcc agauacgcga gcuccgggag aaaagugaaa      300

aauucgccuu ccaagcagag gucaacagaa ugaugaaacu cauaauuaac ucccuauaca      360

aaaacaaaga aauauuccug cgggaacuaa ucuccaacgc cagcgacgcc uuagacaaaa      420

uacgacucau cagccugaca gacgaaaacg ccuugagcgg gaacgaggaa cuaaccguga      480

aaauaaaaug cgacaaagag aagaaccugc uacacguaac ggauacggga guaggcauga      540

cacgagaaga acucgucaaa aaccucggaa ccauagccaa gagcggcaca agcgaguucc      600

ucaacaaaau gacagaagcc caggaggacg gccaaucaac gagugagcuu auaggccaau      660

ucgggguagg guucuacagc gcguuccuag uagcggacaa aguaauaguc acaagcaaac      720

acaauaacga uacacagcac auaugggaau cagacagcaa cgaauuuagc gugaucgcgg      780

acccgcgggg aaacacgcuu ggcagaggaa ccaccaucac ucuaguacuc aaggaagagg      840

cuucagacua ucuagaacug gacacaauca aaaaccucgu aaagaaauac agccaauuca      900

uaaacuuccc gauauacguc uggagcucga aaacagaaac aguagaggag ccgauggagg      960

aggaagaggc agccaaagaa gaaaaagaag aaucggacga cgaagcggca gucgaagaag     1020

aagaggaaga gaaaaagccc aaaaccaaga aaguagagaa aaccguaugg gacugggaac     1080

ucaugaacga cauaaaaccc auauggcagc gcccgagcaa agaagucgag gaagacgaau     1140

acaaagccuu cuacaagagc uucagcaaag aaagcgacga cccgauggcc uauauacacu     1200

ucacagccga aggagaggug acguucaaaa gcauccucuu cgucccgacg agcgccccca     1260

ggggacucuu cgacgaauac gggaguaaga aaagcgacua caucaaacua uacguccgac     1320

ggguguucau aaccgacgac uuccacgaca ugaugcccaa guaccugaac uucgucaaag     1380

gagugguaga uucagaugac cugccacuca acguaagcag agagacgcuc caacagcaca     1440

aacugcucaa gguaauacgc aagaagcuag ucaggaaaac gcucgacaug aucaaaaaga     1500

uugcggacga uaaguacaac gacacguucu ggaaggaguu cggaacgaac auaaaacuag     1560

gcguaaucga agaccacagc aaccgaacaa gacucgcaaa acuccucaga uuccagagca     1620

gccaucaccc cacagacaua acaagccugg accaauaugu ggaacgaaug aaagaaaaac     1680

aggacaaaau cuacuucaug gcgggaucca gccgcaaaga ggcagaaagc agccccuucg     1740

uagaacgacu ccuaaagaaa ggcuacgaag ucaucuacuu gaccgaacca guagacgaau     1800

acugcaucca ggcccuuccc gaguucgacg gcaagagauu ccaaaacguc gcgaaggaag     1860

gcguaaaauu cgacgaaagc gagaagacga aagaaucgag ggaagcaguc gagaaagagu     1920

ucgaaccacu gcucaacugg augaaagaca aagcgcuaaa agacaagaua gaaaaagcgg     1980

uaguaucgca acggcugacc gaaagcccau gcgcccuagu cgcgagccaa uacggcugga     2040

gcgggaacau ggaaagaauu augaaagcgc aagccuacca gacaggaaag gacaucagca     2100

ccaacuacua cgccagccaa aagaagacgu ucgaaaucaa cccaagacac ccgcuaauaa     2160

gagacaugcu acgaaggauc aaggaagacg aggacgacaa gaccgugcuc gaccucgcgg     2220

ucgugcuauu cgaaacggcc acgcuuagaa gcggauaccu gcuacccgac acgaaagccu     2280

acggcgaccg aaucgaacgc augcuaaggc ucagucuaaa cauagacccc gacgcgaaag     2340

uggaagagga accagaggag gaaccagaag aaacggcaga ggacaccacc gaggacacag     2400

aacaggacga ggacgaggag auggacgucg gaacggacga agaggaagaa accgcaaagg     2460

aaucgaccgc agaaaaggac gagcuauaag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  7214
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt11)

<400>  7214
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccgcgaau uacgagcccu acuacuaugg ggucgccgac      120

uccgcccacu acuccgagcc cccgcacucg ccgcaguccc uggaggaaaa cccauacucu      180

gcccccgaag aacaacagcu caacucggcc cccgucgcaa cccagccugg ucgcuccagg      240

ccggccgacu cuucuccaca caaaccgccg aagacaaaga agaaccccuc cacagcauaa      300

ucagcagcac cgaguccgua caaggaagca ccuccaaaca cgaguuccag gccgaaacca      360

agaaacuucu cgacaucgua gcccgaaguc uauacuccga aaaagaaguc uucauccgag      420

aacuuaucuc uaacgcaucc gacgcacucg aaaaacuacg acacaaacuc guaucagacg      480

gucaagcacu acccgaaaug gaaauacauc uacaaaccaa cgcagaaaaa gguaccauaa      540

caauucaaga cacgggaaua ggaaugacgc aggaggaacu cgucucaaac cuaggcacua      600

uagcccgaag cggcagcaaa gccuuccucg acgcccucca aaaccaagcc gaagccuccu      660

ccaaaaucau cggucaguuc ggcguaggcu ucuauuccgc cuucauggua gcagaccgag      720

ucgaaguaua uucucgcuca gcagcccccg gcucccuagg cuaccaaugg cuauccgacg      780

gcagcggcgu guucgaaaua gcagaagccu cgggcguccg uacaggcacc aaaaucauca      840

uacaccuaaa aagcgacugc aaagaauuua gcucagaagc ccgcguccga gacgucguca      900

ccaaauauuc aaauuucguc ucauuuccac ucuaucuaaa cggcagacgc augaacacgc      960

uccaagccau cuggaugaug gacccaaaag acguccgcga auggcagcau gaagaguucu     1020

accgcuacgu agcacaagcg cacgacaaac cacgcuacac ccuccacuac aaaacggacg     1080

ccccacuaaa cauccgcucc aucuucuacg uaccggacau gaaacccagc auguucgacg     1140

uaucccgcga acucggcuca ucgguagcac ucuacucuag gaaaguccuc auacaaacaa     1200

aagccaccga cauccuacca aaauggcuuc gauucaucag aggcgucguc gacagugaag     1260

acaucccccu caaccucuca cgagaacucc uacaagaauc cgccuuaauc cgaaaacucc     1320

gcgacguacu ucaacagcgu cucauaaaau ucuucaucga ucaauccaag aaagaugcag     1380

aaaaauacgc caaauucuuc gaagacuacg gccucuucau gcgggaaggc aucguaacag     1440

caaccgagca agaggucaaa gaggacauag caaaacuccu cagauacgag uccagcgccc     1500

uucccucggg ccaacuaacu agccuaagcg aauacgccuc acguaugaga gcaggcaccc     1560

gcaacaucua cuaccucugc gccccaaacc gacaccucgc agaacacuca cccuacuacg     1620

aggccaugaa aaagaaagac accgaagucc uguucugcuu ugaacaauuc gacgaacuga     1680

cccuacuaca ccucagagag uucgacaaaa agaaacucau cagcgucgag acggacaucg     1740

ucguagacca cuacaaagaa gaaaaauucg aggaccgcag cccagccgca gaaugccuau     1800

cggaaaaaga aaccgaagaa cucauggccu ggaugcggaa cguccuaggc uccagaguaa     1860

ccaacguaaa agucacacuc agacuagaca cccaccccgc cauggucacc guacuagaaa     1920

ugggagcugc ccgacacuuc cuacgaaugc aacaacuagc aaaaacacag gaggaacgcg     1980

cccaacuccu ucaaccaacc cucgaaauaa acccccgaca cgcccuaaua aagaaacuaa     2040

aucaacugag ggccuccgag cccggacucg cccaacuucu agucgaccag aucuacgaaa     2100

acgccaugau cgcggcaggc cuaguagacg acccccgcgc caugguggga cgacuaaaug     2160

aacuacuugu caaagcacua gagcgacauu aaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  7215
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt11)

<400>  7215
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaaaaucu ccucccuccc cacccaacuc uucaaaugcu      120

gcuucugcga cuuccuaaaa gucaaaaugc acaccauguc cuccucccac cucuucuacc      180

uagcccucug ccuccuuacc uucaccuccu ccgccaccgc cggccccgaa acccucugcg      240

gcgccgaacu cgucgacgcc cuccaauuug ucugcggcga ccgcggauuc uacuucaaca      300

aacccaccgg cuacggcucc uccucccgcc gcgcacccca aaccggcauc gucgacgaau      360

gcugcuuccg cuccugcgac cuccgccgcc ucgaaaugua cugcgcaccc cucaaacccg      420

ccaaauccgc ccgcuccguc cgcgcccaac gccacaccga caugcccaaa acccaaaaag      480

aaguccaccu caaaaacgcc ucccgcggcu ccgccggcaa caaaaacuac cgcauguaag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  7216
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt11)

<400>  7216
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggcaucccca ugggcaaauc caugcucguc cuccuaaccu      120

uccucgccuu cgccuccugc ugcaucgccg ccuaccgacc cuccgaaaca cucugcggcg      180

gcgaacucgu cgacacccuc caauucgucu gcggcgaccg cggcuucuac uucucccgcc      240

ccgccucccg cgucucacgc cgcucccgcg gcaucgucga agaaugcugc uuccgcucuu      300

gcgaccucgc ccuccucgaa accuacugcg ccacccccgc aaaauccgaa cgcgacgucu      360

ccaccccccc cacaguacuc cccgacaacu ucccccguua ccccgucggc aaauucuucc      420

aauacgacac cuggaaacaa uccacccaac gccuccgccg cggacuaccc gcccuacucc      480

gcgcccgccg cggccacguc cuagcaaaag aacucgaagc cuuccgagaa gccaaacgcc      540

accgcccccu caucgcccuc cccacccaag accccgccca cggaggcgcc ccccccgaaa      600

uggccuccaa ccgcaaauaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  7217
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt11)

<400>  7217
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuccuucu ccaccuccgc cuucggcccc gucgccuucu      120

cccucggccu ccuacucgua cuccccgccg ccuucccagc ccccgucccc ccaggcgaag      180

acuccaaaga cgucgccgcc ccccaccgcc aaccucucac cucauccgaa cgcaucgaca      240

aacaaauacg cuacauccuc gacggcaucu ccgcccuccg caaagaaacc ugcaacaaau      300

caaacaugug cgaauccuca aaagaagccc ucgccgaaaa caaccuaaac cuccccaaaa      360

uggccgaaaa agacggcugc uuccaauccg gcuucaacga agaaacaugc cucgucaaaa      420

uaaucaccgg acuccucgaa uucgaagucu accucgaaua ccuacaaaac cgcuucgaau      480

cauccgaaga acaagcccgc gccguccaaa ugucaaccaa aguccucauc caauuccucc      540

aaaaaaaagc caaaaaccuc gacgccauca caacccccga ccccaccacc aacgccuccc      600

uacucaccaa acuccaagcc caaaaccaau ggcuccaaga caugaccacc caccucaucc      660

uccgcuccuu caaagaauuc cuccaauccu cccuccgcgc ccuccgacaa auguagggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  7218
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt11)

<400>  7218
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuccugu ggcuccgcgg auuccuccua gcaagcugcu      120

ggauaauagu acgaagcucc ccaacaccag gcagcgaggg ccacagcgcc gcacccgacu      180

gcccauccug cgcacucgcc gcccucccaa aagacguccc gaacagccaa cccgaaaugg      240

ucgaagcggu caagaaacac auacucaaca ugcuacaccu aaagaaacgc ccagacguaa      300

cacagccagu ccccaaagcc gcacuacuaa acgcgauccg aaaacuacac guaggcaaag      360

ugggagaaaa uggcuacguc gaaaucgaag acgacauagg cagacgagca gaaaugaacg      420

aacuaaugga acaaacaagu gaaauaauca cauucgccga gagcggcaca gcccggaaaa      480

cccuacacuu cgaaaucuca aaagaaggau ccgaccucag cgucguagaa cgagccgaag      540

uguggcuauu ccucaaaguc cccaaagcca acagaaccag aaccaaaguc acaaucagac      600

ucuuccaaca gcaaaaacac ccgcaaggaa gccucgacac aggcgaagaa gcagaggaag      660

ucggacucaa aggugaacgc agcgaacucc uccuguccga aaaagucguc gacgcccgaa      720

aaagcacaug gcacguauuc ccaguaagca gcuccaucca acgccugcua gaccaaggga      780

aaucaagccu ggacguccgc auagcaugcg aacaaugcca agaaagcggc gcaagccuag      840

uacuacuagg gaaaaagaaa aagaaagagg aagaaggaga aggaaagaag aaaggaggcg      900

gagaaggugg agcaggcgcc gacgaagaaa aagaacaaag ccaccggcca uuccucaugc      960

uacaagccag acaaagcgaa gaccacccac accgacgacg ccgacgaggc cucgaaugcg     1020

acggaaaagu caauauaugc ugcaagaaac aauucuucgu cagcuucaaa gacauagggu     1080

ggaacgacug gaucauagcc ccaagcggcu accacgccaa cuacugcgaa ggagaaugcc     1140

caagccacau cgccggaaca uccgggagca gccugagcuu ccacagcacg guaauaaacc     1200

acuaccgcau gcgcggccac agcccauucg ccaaccucaa aagcugcugc guacccacca     1260

aacuacgccc aauguccaug cucuacuacg acgacgggca gaacaucaua aagaaagaca     1320

uacagaacau gaucgucgaa gagugcggcu gcuccuaagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  7219
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt11)

<400>  7219
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggccuac caggacgagc ccucggcgcc gcaugccucc      120

uucuccucgc cgccggaugg uuaggccccg aagcaugggg cucacccacc ccaccaccca      180

ccccagccgc acccccaccc ccacccccac caggaucccc aggaggcagc caagacacau      240

gcaccucgug cggaggcuuc agacgcccug aagaacuagg ccgagucgac ggcgacuucc      300

ucgaagccgu gaaacgccau auacucuccc gacuccaaau gcgcggccga cccaacauaa      360

cccacgccgu acccaaagca gcuaugguaa ccgcccuccg caaacuccau gccggcaaag      420

uccgagaaga cggccgaguc gaaauccccc accucgacgg acacgccucc cccggcgccg      480

acggccaaga acgaguauca gaaaucaucu ccuucgcuga aaccgacggc cuggcauccu      540

cccgaguccg ccucuacuuc uuuauaucca acgaagguaa ccaaaaccuc uucgucgucc      600

aagccucacu auggcucuac cuaaaacuac uccccuacgu acucgaaaaa ggcagccgcc      660

gcaaaguccg cguaaaaguc uauuuccaag aacaaggcca cggcgaccgc uggaacaugg      720

uagaaaaacg ugucgaccuc aaaagaucag gcuggcacac cuucccccua accgaagcua      780

uccaagcacu cuucgaacga ggagaacgaa gacucaaccu cgacguacaa ugcgacucuu      840

gccaagaacu cgcgguaguc ccaguauucg ucgaccccgg cgaagaaucc cacagacccu      900

uuguaguagu acaagcgcga cucggcgacu cucgacaccg aauccgcaaa cgcggccuag      960

aaugcgacgg acgcacaaac cucugcugcc gccaacaauu cuucauagac uuccgccuaa     1020

ucggcuggaa cgacuggauc auagccccca ccggcuacua cggcaauuac ugcgaaggcu     1080

caugccccgc auaccucgcc ggcguccccg gcucagcauc cucuuuccac accgccgucg     1140

uaaaccaaua caggaugcgc ggacuuaacc caggaacagu caauuccugc ugcauaccca     1200

ccaaacucag caccaugucc augcucuacu ucgacgacga auacaacauc gucaaacgcg     1260

acguccccaa caugaucguc gaagaaugcg gaugcgcaua aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  7220
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt11)

<400>  7220
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcccuccgug uuuuacugcu cacagcacuc acacuguguc      120

acggauucaa ccuagacacc gaaaaugcaa ugaccuucca agaaaacgca cgcggcuucg      180

gacaaucggu aguccaacua caagguucgc gcguagucgu cggcgccccu caagagauag      240

ucgcugcaaa ccaacgaggc ucacucuacc aaugcgacua cucaaccggg ucaugcgaac      300

caaucagacu ccaaguccca gucgaagcag ucaacaugag ccugggucuc agccucgccg      360

ccacaaccuc acccccacaa cucuuagcau gcggaccaac cguccaucag accugcucgg      420

aaaacaccua cguaaaaggc cuaugcuuuc ucuuuggguc caaccuacga cagcagcccc      480

aaaaauuccc cgaagcccuc cgaggauguc cgcaagaaga cagcgacaua gccuuucuca      540

uugacggcuc cggauccaua auaccacacg acuuccgccg gaugaaggaa uuugucucaa      600

caguuaugga acaacucaag aaauccaaaa cacucuucuc ccugaugcaa uacagcgagg      660

aguucagaau ccacuucacc uucaaagagu uccagaacaa ccccaacccc cgcucacugg      720

uaaaaccaau aacucaacuc cucggcagga cacacacggc cacgggcauc aggaaggucg      780

ugcgcgaacu cuucaacaua acaaauggug cacgcaaaaa cgccuucaaa auccuugugg      840

ucauaaccga cggcgaaaaa uucggggacc cauuaggaua cgaagacgua auccccgaag      900

cggacagaga gggaguaauc cgauacguca ucggcguugg ggacgccuuc cguagcgaaa      960

aaucccgcca ggaacucaac acaauugccu ccaaaccgcc ccgagaccac gucuuccaag     1020

ucaacaacuu cgaagcccuc aaaaccaucc aaaaccaacu ccgagagaaa auauucgcca     1080

uagaaggaac ccaaaccggc agcuccagcu ccuucgaaca ugaaaugucc caagaaggcu     1140

ucagcgccgc gaucaccucc aacggcccuc uacucucuac cgucggauca uacgacuggg     1200

cuggcggcgu cuuccuuuac accuccaagg aaaaaucgac auucaucaac augaccagag     1260

ucgauucuga caugaacgac gcauaucucg gcuacgccgc ugcuaucauu cuacgcaaca     1320

gagugcaauc ucuaguauua ggagccccuc guuaccaaca caucggccua guggcaaugu     1380

uccgucaaaa caccgggaug ugggaaagca acgcgaacgu caagggcacc caaaucggcg     1440

cauacuucgg agcuucucuc ugcucugugg acgucgacuc aaacggaagc acugaucucg     1500

uucuuaucgg agcaccccac uacuaugagc agacucgagg aggccaagua ucagucuguc     1560

cacucccccg uggccgagcc cgcuggcaau gcgacgcggu ucuauauggc gaacaagguc     1620

aacccugggg cagguucggu gccgcgcuca ccguccuugg agacgucaac ggcgacaaac     1680

ucaccgacgu agcaaucggc gcaccuggcg aggaagacaa ccgcggcgca guguaccucu     1740

uccacggcac cuccggcagc ggcaucucac ccucccacuc acaacgcaua gccggcucua     1800

aacugucccc cagacugcaa uacuucgggc aaagccuauc cgguggacaa gaccucacga     1860

uggacggccu aguagaucug acgguuggcg cgcaagggca uguacuucua cuacgauccc     1920

aaccaguacu acgugucaag gcaaucaugg aguucaaucc acgggaaguc gcacgaaacg     1980

ucuucgaaug caacgaccaa guugucaagg gcaaagaagc cggcgaaguc agaguguguc     2040

ugcacguaca aaagagcaca cgugaucgac ugcgagaagg acaaauccag uccgugguca     2100

ccuacgaccu agcccuagac uccggaagac cccacagccg ugccgucuuc aacgaaacca     2160

aaaauucaac ccgccggcaa acccaggugc uaggccuuac ccaaacuugc gagacgcuca     2220

aacuacaacu gcccaacugu aucgaagacc cagucucacc aaucguacua cgccuuaauu     2280

uuucccuagu cggcacaccc cucucagcau ucggaaaccu ccgacccguc cucgccgaag     2340

acgcccaacg acuuuucacc gcccuauucc ccuucgaaaa gaacugcggc aacgacaaca     2400

uaugucaaga cgaccucagc aucaccuucu cuuucauguc gcucgacugc cuagugguag     2460

gcggaccccg agaauuuaac gucacaguca ccguaagaaa cgacggagag gauuccuaca     2520

gaacgcaagu uacauucuuc uucccgcucg accucucgua ccgcaaaguc ucgacccuuc     2580

aaaaccaacg aucucaacga ucuuggaggc ucgcauguga aucagccucg ucaacagaag     2640

uaaguggcgc ccucaaaucg accuccuguu ccauaaacca cccaaucuuc cccgagaaca     2700

gcgaagucac auucaacaua acauucgacg uugacucuaa agcaucacuc ggcaacaaac     2760

ucuuacugaa agccaacguc accagcgaaa acaacaugcc aagaacaaac aaaacagagu     2820

uccaacucga acucccaguc aaguaugccg uauacauggu cgucaccagc cacggaguau     2880

ccacaaaaua ccucaacuuu accgccagcg aaaacacguc cagaguaaug caacaccaau     2940

accagguauc caaccuuggu caacgcaguc uacccaucuc ccuaguguuc cucguucccg     3000

ucagacuaaa ccagacagua auaugggacc guccacaagu aacauucucu gaaaaccucu     3060

ccuccacaug ucacacuaaa gaacgacucc cuagccauuc cgacuuucuu gcagagcuuc     3120

gcaaagcccc uguugugaac ugcucaaucg cgguaugcca gcgcauacag ugcgacauac     3180

cauucuuugg gauacaggaa gaguucaacg cgacucucaa agguaaccuc agcuucgacu     3240

gguauaucaa gaccucacau aaccaccucc uaauaguauc cacagccgaa auccucuuca     3300

acgacagcgu cuucacauug cugcccggcc aaggagcuuu cguacgaucg cagacagaaa     3360

cuaaaguaga accuuucgaa gucccgaacc cgcucccgcu aaucgucgga uccuccguug     3420

gcgggcuacu ccuucuugcc cucaucacag cagcacugua uaagcucggc uucuucaagc     3480

gccaauacaa agauaugaug uccgaaggcg gcccgcccgg ggccgaaccc caguaaggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  7221
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt11)

<400>  7221
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucccuca aaaccuuacc guuccuccua cuacuacacg      120

uccaaaucuc caaagccuuc ccugucucca gcaaagagaa aaacacuaaa accguacagg      180

acuaccucga aaaauucuac caacuacccu caaaccagua ccaguccacc cgcaaaaacg      240

gcacaaacgu gaucgucgaa aagcuaaaag aaaugcaacg cuucuucggc cuaaacguca      300

caggcaaacc caacgaagaa acccucgaca ugaugaagaa accccgaugc ggcguccccg      360

acuccggcgg cuucaugcuc acacccggua accccaaaug ggaacgaacc aaccuaaccu      420

accgcauacg aaacuacaca ccccaacucu cagaagccga agucgaacga gcuaucaaag      480

acgcauuuga acucuggucc gucgcaucac cccucaucuu cacccgcauc ucucaaggcg      540

aagccgacau aaauaucgcc uucuaucaaa gagaccacgg cgacaacucc cccuucgacg      600

gcccgaacgg uauccucgca cacgccuucc aaccaggcca aggaaucggc ggcgaugccc      660

acuucgacgc agaagaaacc uggacaaaca ccucagccaa cuacaaccuc uuccucgucg      720

ccgcgcacga guucggacau ucccucggcc uagcccacuc cuccgacccc ggugcacuca      780

uguacccaaa cuacgccuuc cgcgaaacca gcaacuacuc acucccccaa gacgacauag      840

acggcaucca agccauauac ggacuaucau ccaaccccau ccagccaacc ggacccucaa      900

cccccaaacc cugcgaucca ucccucaccu ucgacgccau caccacccua cguggagaga      960

uccucuucuu caaagaucga uauuucuggc gccgacaccc ccaacugcaa cggguugaaa     1020

ugaacuucau cagccucuuc uggccuucac uacccaccgg aauccaagcc gccuaugaag     1080

acuuugaccg cgaccucauc uuccucuuca aaggaaacca auacugggcc cucucggguu     1140

acgacauccu ucaaggcuac ccuaaagaca uaucaaacua cggauuccca ucguccgucc     1200

aagccaucga ugccgcaguu uucuaccgcu ccaaaaccua cuucuucguc aacgaccaau     1260

ucuggcgcua ugacaaccaa cgccaauuca uggaaccagg auaccccaaa uccaucuccg     1320

gcgccuuccc cggcaucgaa agcaaagucg acgcagucuu ccaacaagaa cacuucuucc     1380

acguuuucuc aggcccucgc uacuacgccu ucgaccuaau cgcccaacga gucacccgag     1440

ucgcccgagg aaacaaaugg cuuaacugcc gcuacggaua gggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  7222
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt11)

<400>  7222
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucccucuggc aaccucucgu auuaguacuc cuaguccuug      120

gaugcugcuu ugccgcuccu cgacaacgcc aauccacacu cguccuuuuc ccaggggauc      180

uaagaaccaa ccuuaccgac cggcaacuag cagaggaaua ccuauaccgc uauggauaca      240

caagagucgc cgaaaugaga ggagaaucga aaagccucgg accagcccuc cuacuacuac      300

aaaaacaacu cucccugccc gaaacuggcg aacucgacuc ugccacucua aaagcaauga      360

ggaccccacg augcggcguc cccgaccuag gcagauucca aaccuucgaa ggcgaucuaa      420

aauggcacca ccacaacaua accuacugga uccaaaacua cucagaagac cucccccgag      480

ccguaauaga cgaugccuuc gcaagagcuu ucgcccucug gucggcaguc acuccccuca      540

ccuuuaccag aguauacucc cgagacgccg acauagucau ccaauucggc gucgccgaac      600

acggcgacgg cuaccccuuc gacggaaaag auggacuccu cgcucacgcg uucccaccag      660

gcccagguau ccaaggcgau gcucacuucg acgacgacga acuauggucu cucggaaaag      720

gggucgucgu ccccacccga uucggaaacg cagacggcgc cgcuugccac uuccccuuca      780

ucuucgaagg acguuccuac agcgccugca cgaccgacgg aagauccgau ggacuaccau      840

ggugcucaac gaccgccaac uacgacacag acgacagauu cggauucugu cccucagaac      900

gucucuacac acaagacggc aacgccgaug gcaaacccug ccaauucccc uucauauucc      960

aaggccaauc cuacuccgcc ugcacaaccg acggacgcuc ugacggcuac cgauggugcg     1020

cuacaacagc aaacuaugau cgagacaagu uauuuggauu cugccccacc cgcgccgauu     1080

ccaccguaau gggugggaac uccgcaggag aacucugcgu cuuccccuuc accuuccucg     1140

gaaaagagua cagcacaugc accuccgaag gccgaggcga cggccgccua uggugcgcca     1200

ccaccuccaa cuuugacuca gacaagaaau gggguuucug ccccgaccaa gguuacagcc     1260

ucuuccucgu cgccgcacau gaauuuggac acgcauuagg ccuagaccac ucgucagucc     1320

ccgaagcccu cauguacccc auguacagau ucacugaagg cccaccccuc cacaaagacg     1380

acgucaacgg aauccgccau cucuacggcc cccgaccaga accugaacca cgcccaccca     1440

caaccaccac accccaaccc accgccccac ccacugucug ccccaccggc ccacccaccg     1500

uccaucccag cgagagaccc accgcgggcc caaccggccc acccuccgca ggccccacug     1560

gacccccaac cgcaggaccc uccaccgcua cuaccguucc acuaucccca gucgacgacg     1620

cuugcaacgu caacaucuuc gacgccauag cugagauagg aaaccagcuc uaccuauuca     1680

aagacggaaa auacuggcga uucuccgagg gacgcggcuc ccgcccccaa ggaccauuuc     1740

uaauagcaga caaguggccc gcacucccac gcaaacuuga cuccguuuuc gaggaaagac     1800

ucuccaagaa acuauucuuc uuuuccggcc gacaagucug gguuuacaca ggcgccuccg     1860

uacucggucc ucgccgccuu gacaaacuag ggcucggcgc agacgucgcc cagguaacag     1920

gagcucuccg aagcggaagg ggcaaaaugu uacucuucuc cggccgucga cucuggcgau     1980

ucgacguaaa agcccaaaug guagauccca gaagcgccag cgaagucgac cgcauguucc     2040

caggaguccc ccuugauacc cacgacgucu uccaauaccg cgaaaaagcc uacuuuugcc     2100

aagaccgcuu cuacuggcgc gucucuagca gaucagaacu uaaccaagua gaccaaguag     2160

gcuacgucac cuacgacauc cuacagugcc cagaagacua aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  7223
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt11)

<400>  7223
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccccggcg uacucgcagc cuuccuauuc cuauccugga      120

cccacugccg cgcauuaccc cuccccucag gaggcgauga agacgaccuu uccgaagaag      180

accugcaauu cgccgaacgc uaccuccgau ccuacuacca ccccaccaac cucgccggca      240

uacucaaaga aaacgcagcc ucauccauga cagaacgccu ccgcgaaaug caauccuucu      300

uuggccucga agucaccgga aaacuugacg acaacacgcu agacgucaug aaaaaaccca      360

gaugcggagu ccccgacguc ggcgaauaca acgucuuccc cagaacccua aaauggucaa      420

aaaugaaccu caccuacaga auagucaacu acaccccuga caugacccac uccgaaguag      480

aaaaagccuu caaaaaagcc uucaaagucu ggucugacgu uaccccccuc aacuucaccc      540

gacuccacga cggcaucgcc gacauaauga ucuccuucgg aaucaaagaa cacggcgacu      600

ucuaccccuu cgacggacca ucaggccuac ucgcccacgc cuucccacca ggacccaacu      660

acggaggcga cgcccacuuc gaugacgacg aaaccuggac cuccuccucc aaaggcuaca      720

accucuuccu aguagccgca cacgaauucg gccacucacu aggacuagac cacuccaaag      780

accccggcgc ucuuauguuc cccaucuaca ccuacacugg gaaaucccac uucaugcucc      840

ccgacgacga cguacaaggc auccaaagcc ucuacggccc gggcgacgaa gaucccaacc      900

ccaaacaccc caaaacacca gacaaaugcg accccucacu aucacuagac gcaaucaccu      960

cccuccgugg cgaaacuaug aucuucaaag accgauucuu cuggcgcuua cacccccaac     1020

aagucgacgc cgaacucuuc cuuaccaaau cauucuggcc cgaacucccc aaccgcaucg     1080

acgccgccua cgaacacccc agccaugacc ucaucuuuau cuuccgcggg agaaaauucu     1140

gggcacuaaa cggauacgac auacucgaag gcuacccaaa aaaaaucucc gaacuaggcc     1200

ucccaaagga agucaaaaag aucuccgcag caguacacuu cgaagacacc ggcaaaaccc     1260

uccuauucuc agguaaccaa guauggcgcu acgacgacac caaccacauc auggacaaag     1320

acuacccccg ccucaucgaa gaagacuucc ccggcauagg cgacaaaguc gacgccgucu     1380

augaaaaaaa cggcuacaua uacuucuuua acggccccau ccaauuugaa uacuccauau     1440

gguccaaccg caucguacgc guuaugccag ccaacuccau ccucuggugc uaaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  7224
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt11)

<400>  7224
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaaccccga acaccaccga agauuacgac accacaaccg      120

aguucgacua cggcgacgcc acccccugcc aaaaagucaa cgaacgcgcc uucggcgccc      180

aacuccuccc accccuuuac ucccucgucu ucgucaucgg ccucgucggc aauauccucg      240

uaguccucgu ccucguccaa uacaaacgac ucaaaaacau gaccuccauc uaccuacuca      300

accuugccau cuccgaccuc cucuuccucu ucacccuccc cuucuggaua gacuacaaac      360

ucaaagacga cugggucuuc ggcgacgcca ugugcaaaau ccucucgggc uucuacuaca      420

caggacucua cuccgaaauc uucuucauca uccuccuaac uaucgaccgc uaccuagcca      480

ucguccacgc cgucuucgca cuacgcgccc gcaccguaac cuucggcguc aucaccucaa      540

ucaucaucug ggcccucgcc auccucgccu ccaugcccgg ccucuacuuc ucaaaaaccc      600

aaugggaguu cacacaccac acaugcucac uccacuuccc ccacgaaucc cuacgcgaau      660

ggaaacucuu ccaagcccuc aaacucaacc uauucggccu aguccuccca cuacucguca      720

ugaucaucug cuacacaggc aucaucaaaa uacuccuccg ccgccccaac gaaaagaaau      780

ccaaagcagu ccgccucauc uuugucauaa ugauaaucuu cuuccuauuc uggacccccu      840

acaaccucac cauccucauc ucaguauucc aagacuuccu cuucacccau gaaugcgaac      900

aaucacgcca cuuagaccuc gccguccaag ucaccgaggu cauugccuac acccacugcu      960

gcgucaaccc aguaaucuac gccuucgucg gcgaacgcuu ccgcaaauac cuccgucaac     1020

uauuccaccg acgcgucgcc guacaccucg ucaaauggcu ccccuuccua ucugucgacc     1080

gacuagaacg cgucuccucc acaagcccaa gcaccggcga acacgaacuc uccgccggcu     1140

ucuagggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  7225
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt11)

<400>  7225
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgcacacucg ccugccuccu acuccucggc ugcggcuacc      120

ucgcacacgu ccucgccgaa gaagccgaaa ucccccgaga agucaucgaa cgacucgccc      180

gcucccaaau ccacuccauc cgcgaccucc aacgccuccu cgaaaucgac uccgucggcu      240

ccgaagacuc ccucgacacc ucacuccgcg cccacggagu ccacgccacc aaacacguac      300

ccgaaaaacg accccucccc auccgccgaa aacgcuccau agaagaagcc guccccgccg      360

ucugcaaaac ccgcaccguc aucuacgaaa ucccccgcuc ccaagucgac cccacauccg      420

ccaacuuccu caucuggccc cccugcguag aagucaaacg cugcaccggc ugcugcaaca      480

cauccuccgu aaaaugccaa cccucccgcg uacaccaccg cuccgucaaa gucgccaaag      540

ucgaauacgu ccgcaaaaaa cccaaacuaa aagaagucca gguccgccuc gaagaacacc      600

ucgaaugcgc cugcgccacc accucccuca acccagacua ccgcgaagaa gacaccggcc      660

gcccccgcga auccggcaaa aaacgcaaac gcaaacgccu gaaacccacc uaaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  7226
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt11)

<400>  7226
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaccgaugcu gggcccucuu ccucagccuc ugcugcuacc      120

uacgacuugu aucagccgaa ggcgacccaa ucccagaaga acuauacgaa augcuguccg      180

accacuccau ccgcuccuuc gacgaccucc aacgccuccu ccacggugac cccggcgaag      240

aagacggcgc cgaacuagac cuuaauauga cccgcuccca cuccggcgga gaacucgaau      300

cacucgcccg cggacgccgc ucccuaggcu cccucaccau cgccgaacca gccaugaucg      360

ccgaaugcaa aacacgcacc gaaguauucg aaaucucacg ccgacucauc gaccgcacca      420

acgccaacuu ccuugucugg cccccaugcg ucgaagucca acgcugcucc ggcugcugca      480

acaaccgcaa cguacaaugc cgacccacac aaguacaacu ccgcccaguc caaguacgca      540

aaaucgaaau cguccgcaaa aaaccaaucu ucaaaaaagc cacagucacc cucgaagacc      600

accucgccug caaaugcgaa accguagccg ccgcacgccc cgucacccgc ucacccggcg      660

gaucacaaga acaacgugca aaaacccccc aaacccgcgu cacaauccgc accguccgcg      720

uccgccgccc ccccaaagga aaacaccgca aauucaaaca cacacacgac aaaaccgccc      780

ucaaagaaac ccuaggcgcc uaaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  7227
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt11)

<400>  7227
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccucuucg gccuccuccu ccucaccucc gcccuggccg      120

gccagcgcca aggcacccag gccgaaucca accucuccuc caaauuccaa uucuccucca      180

acaaagaaca aaacggcguc caagaccccc aacacgaacg aaucaucacc gucucaacaa      240

acggcucaau acacucacca cgcuuccccc acaccuaccc aagaaacacc guccucgucu      300

ggcgccuagu cgccgucgaa gaaaacguau ggauccaacu caccuucgac gaacgcuucg      360

gccucgaaga cccagaagac gacaucugca aauacgacuu cguagaaguc gaagaaccua      420

gcgacggcac cauacucgga cguuggugcg gcuccggcac cguccccggc aaacaaaucu      480

ccaaaggcaa ccaaauccga auacgcuucg uauccgacga auacuuccca uccgaacccg      540

gcuucugcau ccacuacaac aucgucaugc cccaauucac cgaagccguc ucccccuccg      600

uacuaccccc cuccgcccuc ccccucgauc uucucaacaa cgccaucacg gccuucucca      660

cccucgaaga ccuaauacgc uaccuggaac ccgaaagaug gcaacucgau cucgaagauc      720

uauaccgccc cacauggcaa cuccucggca aagccuucgu cuucggcaga aaaucccggg      780

ucguagaccu caaccuccuc accgaagaag uacgccuaua cuccugcaca ccacgcaacu      840

ucuccguauc cauccgagaa gaacucaaac gcaccgacac uaucuucugg cccggcugcc      900

uccucgucaa aagaugcggc ggaaacugcg ccugcugucu ccacaacugc aacgaaugcc      960

aaugcguccc cuccaaagua accaaaaaau accacgaagu ccuacaacuu cgcccaaaaa     1020

ccggcguaag aggccuccac aaaucccuca ccgacgucgc acuagaacac cacgaagaau     1080

gcgacugcgu cugccgcggc uccaccggag gauaaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  7228
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt11)

<400>  7228
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccgccuaa ucuucgucua cacccuaauc ugcgccaacu      120

ucugcuccug ccgagacacc uccgccaccc cacaauccgc cuccauaaaa gcacuccgga      180

augccaacuu acgccgggac gaccuauacc gucgagacga aacaauccaa guaaaaggaa      240

acggcuacgu gcaaucgccc cgauucccaa acuccuaccc acgcaaccuc cuccucaccu      300

ggcgacuaca cucccaagaa aacacucgca uccaacucgu cuucgacaac caguucggcc      360

uggaagaagc cgaaaacgac aucugccgcu acgacuucgu cgaagucgaa gacauaucag      420

aaaccuccac caucauacgc ggccgcuggu gcggccacaa agagguaccc ccccgcauca      480

aaucccgcac aaaccaaauc aaaauaaccu ucaaaucaga cgacuacuuc guagcuaaac      540

ccggauucaa aaucuacuac ucccuccuag aagacuucca acccgccgca gcauccgaga      600

ccaacuggga auccguaacc uccuccauau ccggcguauc cuacaacagc cccuccguca      660

cagaccccac ccuuauagcc gacgcccucg acaaaaaaau cgccgaauuc gacaccgucg      720

aagaucuccu aaaauacuuc aaccccgaau cauggcaaga agaccucgaa aacauguacc      780

uagacacccc acgauaccgc ggacgcucau accacgaccg aaaauccaaa gucgaccucg      840

accgacucaa cgacgacgcc aaacgcuaca gcugcacacc acgcaacuac uccgucaaca      900

uccgcgaaga gcuaaaacuc gccaacguag ucuucuuccc ccgcugccuu cucguccaaa      960

gaugcggcgg caacugcggc uguggaaccg uaaacuggcg cagcugcacc ugcaacucag     1020

gcaaaaccgu caaaaaauac cacgaagucc uccaauucga accaggccac aucaaacgcc     1080

gcggccgagc caaaacaaug gcccucgucg acauccagcu cgaccaccac gaacgcugcg     1140

acugcauaug cuccagccgc cccccucgcu aaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  7229
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt11)

<400>  7229
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccacu ccaaauuccc ugccgcaggc augucccgac      120

cccucgacac cucccuccga cucaaaaccu ucuccucaaa guccgaauac caacucgucg      180

ucaacgccgu ccguaaacuc caagaauccg gcuucuacug guccgccguc accgguggug      240

aagcaaaccu ccuccucucc gcagaacccg ccggcaccuu ccucauccgc gacuccucag      300

accaacgcca cuucuucacc cucucaguca aaacccaauc cggcaccaaa aaccuccgca      360

uccaaugcga aggcggcucc uucucccucc aauccgaccc acgcuccaca caaccugucc      420

cacgcuucga cugcguccuc aaacucgucc accacuacau gccacccccc ggcgcccccu      480

ccuucccauc cccccccacc gaacccuccu cagaaguccc cgaacaaccc ucagcccaac      540

cccuccccgg cucccccccc cgccgcgcau acuacaucua cuccggcggc gaaaaaaucc      600

cacucguacu cucccgcccc cucuccucca acgucgccac ccuacaacac cucugccgca      660

aaaccgucaa cggccaccuc gacuccuacg aaaaagucac ccaacuaccc ggccccaucc      720

gcgaauuccu cgaccaauac gaugcacccc uauaaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  7230
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt11)

<400>  7230
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guccccuccg ccggccaacu cgcccuauuc gcccucggaa      120

ucguccucgc agccugccaa gcccucgaaa acuccaccuc cccccucucc gccgaccccc      180

ccgucgccgc cgccgucguc ucccacuuca acgacugccc cgacucccac acccaauucu      240

gcuuccacgg caccugccgc uuccucgucc aagaagacaa acccgccugc gucugccacu      300

ccggcuacgu cggcgcccgc ugcgaacacg ccgaccuccu cgccgucguc gccgccuccc      360

aaaaaaaaca agccaucacc gcccucgucg ucgucuccau cgucgcccuc gccguccuca      420

ucaucaccug cguccuaauc cacugcugcc aaguccgcaa acacugcgaa uggugccgcg      480

cccucaucug ccgccacgaa aaacccuccg cccuccucaa aggccgcacc gccugcugcc      540

acuccgaaac agucguuuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  7231
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt11)

<400>  7231
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucccucug gccuucgacu gcucccccuc cuccuccccc      120

uccuauggcu ccuaguccua acacccggcc gcccagccgc aggccucucc acaugcaaaa      180

caauagacau ggaacucguc aaacgaaaac gcaucgaagc aauccgcggc caaauacucu      240

cuaaacuucg ccucgccuca ccacccuccc aaggcgaagu cccaccagga ccccuccccg      300

aagccguauu agcucucuac aacuccacac gcgaccgcgu cgcaggcgag agcgccgaac      360

ccgaacccga accugaagcu gacuacuacg ccaaagaagu aacacgcguc cucaugguug      420

aaacccacaa cgaaaucuau gacaaauuca aacaauccac ccacucaauc uacauguucu      480

uuaacacauc agaacuccgc gaagccgucc ccgaaccagu ccuccuuucc cgugccgaac      540

uccgccuacu gcgccucaaa cuaaaaguag aacaacacgu ugaacucuac caaaaauacu      600

caaacaauuc cuggcgauac cucuccaacc gccuccucgc ccccuccgac agccccgaau      660

ggcucucuuu ugacgucaca ggcgucguac gccaauggcu cucaagaggc ggcgaaaucg      720

aaggcuuccg ccucucagcc cauugcucuu gcgacucucg cgacaacacc cuccaagucg      780

acaucaacgg cuucaccacc ggccgacgcg gcgaccucgc caccauccac ggcaugaacc      840

guccuuuccu acuucuaaug gccacacccc ucgaacgcgc ccaacaccuc caaucaucac      900

gccacagacg cgcccucgac accaacuacu gcuucuccuc caccgaaaag aacugcugcg      960

uacgccaacu cuacaucgac uuccguaaag accucggcug gaaauggauc cacgaaccca     1020

aaggcuacca cgccaacuuc ugucuuggcc caugccccua caucuggucc cuagacacuc     1080

aauacuccaa aguccuagcc cuuuacaacc aacacaaccc cggcgcauca gccgcccccu     1140

gcugcguacc ccaagcccuc gaaccacucc ccauagucua cuacguaggc cgaaaaccca     1200

aagucgagca acuauccaac augaucgucc ggucgugcaa augcuccuaa ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  7232
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt11)

<400>  7232
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uccucuccgc cuuccucaua uuacaccucg      120

ucaccguugc ccuaucccuc ucgacuugcu ccacccucga cauggaccaa uucaugcgca      180

aaagaaucga agcaauccga ggccaaaucc ucucaaaacu caaacuuaca ucccccccug      240

aagacuaucc agaacccgag gaaguccccc cugaagucau auccauauac aacagcaccc      300

gcgaccuacu ccaagaaaaa gccucgcgac gagccgcagc cugcgaacgc gaacgcagcg      360

acgaagaaua cuacgccaag gaagucuaca aaaucgacau gccgcccuuc uucccaucag      420

agaaugcuau cccccccacc uucuaccgac cauacuuccg caucguccgc uucgacgucu      480

ccgcaaugga aaaaaacgcc uccaaccucg ucaaagccga auuccgcguc uuccgccugc      540

aaaaccccaa agcccgcguu cccgaacaac gcaucgaacu cuaccaaaua cucaaaucca      600

aagaccucac cucucccacc caacguuaca ucgacucuaa aguagucaaa acacgcgccg      660

aaggcgaaug gcucuccuuc gacguaaccg acgccguaca cgaauggcuc caccacaaag      720

acagaaaccu cggauucaaa aucucccuac acugccccug cugcacuuuc guccccucca      780

acaacuacau aauucccaac aaauccgaag agcuugaagc ccgcuucgcc ggcaucgacg      840

gaaccucgac cuacacuuca ggcgaccaga aaaccauuaa auccacccgc aaaaaaaacu      900

cgggcaaaac accccaccuc cuacucaugc uccucccauc cuaccggcua gaaucccaac      960

aaaccaaccg acgcaaaaaa cgagcccucg acgcagccua cugcuuccgu aacguccaag     1020

acaauugcug ccuacgccca cucuacaucg auuucaaacg ugaccucgga uggaaaugga     1080

uccaugaacc caaaggcuac aacgccaacu ucugcgcagg cgcaugcccc uaccucugga     1140

gcuccgacac ccaacacucc cgcguccuaa gccuuuacaa caccaucaac cccgaagccu     1200

cagccucccc cugcugcguc ucccaagacc ucgaaccacu aacaauccuc uacuacaucg     1260

gcaaaacccc caaaauagaa caacucucca acaugaucgu caaauccugc aaaugcuccu     1320

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  7233
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt11)

<400>  7233
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaugcacc uccaacgagc ccuagucguc cucgcacuac      120

ucaacuucgc aaccgucucc cuaagccuuu ccacaugcac cacccuggac uucggccaca      180

ucaaaaagaa acgugucgaa gccauucgag gccaaauacu cagcaaacuc cgccucacau      240

cacccccaga acccacaguu augacccacg uccccuacca gguccuagcc cuauacaaca      300

gcacccgcga acuccucgaa gaaaugcacg gcgaacgcga agaaggcugc acccaagaaa      360

auacagaguc cgaauauuau gcaaaagaaa uccacaaauu cgacaugauc cagggccucg      420

ccgaacacaa cgagcucgcc gucuguccca aaggcaucac cuccaaagua uucagauuca      480

acgugucauc cgucgagaaa aaccgcacca accucuuccg cgccgaguuc cguguccucc      540

gcgucccaaa ccccuccagc aaacgaaacg aacaacgaau agaacuauuc cagauccucc      600

gccccgacga acacaucgcc aaacaacgcu acauuggggg caaaaaccuc cccacccgcg      660

gaacagccga auggcuaucc uucgacguca ccgacaccgu ccgcgaaugg cuacuaagaa      720

gagaauccaa ccucggccuc gaaaucucca uacacugccc cugccacacc uuccaaccca      780

acggagacau acucgaaaac auccacgaag uaauggaaau caaguucaaa ggagucgaca      840

acgaagacga ccacggccgc ggcgaccuag gccgccucaa aaagcagaaa gaccaccaca      900

acccccaccu aauacuaaug augauacccc cucaccgccu cgacaacccc ggccaaggcg      960

gacaacgcaa aaagcgcgcc cucgacacua acuacugcuu ccgcaaccuc gaagaaaacu     1020

gcugcguccg cccccucuac aucgacuucc gccaagaccu cggguggaaa uggguacacg     1080

aacccaaagg cuacuacgcc aacuucugca gcggaccaug cccauaccuc agaagcgcag     1140

acacaacaca cuccaccguc cucggccucu acaacacccu aaaccccgaa gccucagccu     1200

cccccugcug cguaccacaa gaccuugaac cacucaccau ccucuauuac guaggccgca     1260

cccccaaagu cgaacaacuc ucaaacaugg ucguaaaauc augcaaaugc uccuaaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  7234
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt11)

<400>  7234
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaccagucg cagucugggc cgcccucgcc guaggccuug      120

aacucugggc agccgcccac gcccucccag cacaagucgc auucacuccc uacgcacccg      180

aacccggcuc caccugccgc cuacgcgaau acuaugacca aacagcacaa augugcugcu      240

ccaaaugcuc ucccggccaa cacgcuaaag uauucugcac aaaaaccucu gacaccguau      300

gcgacucaug cgaagacucc acauauaccc aacucuggaa cugggucccc gaaugccucu      360

ccugcggcuc ccgcugcagc ucagaccaag uagaaaccca agcuugcacc cgcgagcaaa      420

accgcaucug cacaugccgc cccggcuggu acugcgcucu cuccaaacaa gaaggcugca      480

gacuuugugc accucugagg aaaugccgac caggcuuugg uguagcaaga cccgguaccg      540

aaaccucaga cgucgucugc aaaccgugug cacccggcac cuucucaaac accaccuccu      600

cuaccgacau cugccgacca caucaaaucu gcaacguagu cgccauccca ggcaacgccu      660

ccauggacgc cguaugcacc ucgaccuccc ccacccgcuc cauggccccc ggcgccguac      720

accuacccca acccgucucc acccgauccc agcacaccca acccacccca gaacccagca      780

ccgccccguc aaccucauuc cuacucccaa ugggccccuc cccacccgca gaaggcucca      840

caggcgauuu cgcccucccc guaggacuaa uaguuggcgu caccgcccua ggccuccuua      900

ucaucggcgu agucaacugc gucaucauga cccaagucaa aaaaaaaccc cucugccucc      960

aacgcgaagc caaaguccca caccucccag ccgacaaagc ccgcggaacc caaggccccg     1020

aacaacaaca ccugcucauc accgcccccu caucaagcuc cuccucacuc gaaucauccg     1080

ccuccgcccu cgaucgacgc gcccccacac gcaaccaacc acaagcccca ggcguagaag     1140

cguccggcgc cggcgaagcc cgcgccucca ccggcucguc cgacuccuca ccaggagguc     1200

acggcaccca aguaaauguc accugcaucg ugaacguuug uuccuccuca gaucacagcu     1260

cccaaugcuc uucccaagcc uccuccacaa ugggcgacac cgauuccagc cccucagaau     1320

cccccaaaga cgaacaaguc ccauucucaa aagaagagug ugccuuccga ucccagcucg     1380

aaacaccaga aacccuacuc gguucaaccg aagaaaaacc ccucccccuc ggcgucccag     1440

acgcaggcau gaaacccucc uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  7235
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt11)

<400>  7235
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccggucaugc gccuguuccc gugcuuucuc cagcuacugg      120

ccgggcucgc gcucccggcc gugcccccgc aacaaugggc gcucucggcc ggaaacggga      180

gcucggaagu ggaagugguc ccguuccagg aagugugggg gcgcucguac ugucgagcgc      240

ucgagcgcuu ggucgauguc gugagcgagu acccgagcga ggucgagcac auguucucgc      300

ccucgugcgu gagcuugcua aggugcacgg gauguugcgg ggacgagaac uugcacugug      360

uaccggucga gaccgcgaac gugaccaugc aauugcucaa gaucaggagc ggggacaggc      420

ccucguacgu ggaauugacc uuuagccagc acgugcgcug ugaaugucgc ccgcucaggg      480

aaaagaugaa gccagagcgc aggcgcccga aagggcgagg gaaaaggcgc agggaaaagc      540

aaagacccac ggacugucac uugugcgggg acgcgguccc gaggcgcuga ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  7236
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt11)

<400>  7236
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug accgauagac agaccgacac agcgcccuca cccucguacc      120

aucucuugcc ggggaggagg agaacgguag acgcggcggc aucgcgcggg caagggccgg      180

aaccagcgcc agggggagga gucgaaggag ugggagcgag aggggucgcg cuaaaacucu      240

ucguccaacu gcugggaugc agcagguucg ggggagcagu gguaagagca ggagaggcag      300

agccaucggg cgcggcaagg agcgcaagcu cgggaaggga ggaaccacag ccagaagaag      360

gggaagagga agaggaaaag gaagaagaaa ggggaccaca auggagacua ggcgcgagaa      420

agccagggag cuggacaggg gaggcggccg ugugcgcgga cucggcacca gccgcaagag      480

cgccgcaggc acuagcaagg gccucgggaa ggggaggaag gguggcaaga cgaggagccg      540

aggaaucagg accaccacac agcccaagca ggcgagggag cgcgagcagg gcagggcccg      600

ggagagcaag cgagacaaug aacuuucucu ugagcugggu acauuggucg cuagcgcucc      660

uacuguaucu gcaccacgcg aaauggagcc aggcagcgcc aauggcagag ggaggagggc      720

agaaccacca cgaagucgug aaauucaugg auguauacca aaggagcuac ugccacccaa      780

uagaaacgcu aguagacaua uuccaggaau auccagauga aauugaauac auauucaaac      840

cgagcugcgu accacucaug agguguggcg gaugcuguaa cgaugaaggg cuagagugcg      900

ugccaacaga agagagcaac auaacaaugc aaauaaugcg aauaaaacca caccaaggac      960

agcacauagg agagaugagc uuccuacaac acaacaagug cgagugcagg ccaaagaaag     1020

acagagcgcg ccaagaaaag aaaagcguaa ggggaaaggg gaagggacag aaaaggaaaa     1080

ggaaaaagag uagauacaaa aguuggagcg uauacguagg agcgagaugc ugcuugaugc     1140

cguggucacu accgggacca cacccgugug ggcccugcag cgagagacga aaacaccuau     1200

ucgugcagga cccgcagacg ugcaagugcu cguguaagaa cacggacucg aggugcaaag     1260

cgagacagcu agagcugaau gaaaggaccu gccgauguga caagcccaga agguagggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  7237
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt11)

<400>  7237
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccucc uaagcugggu ccacuggucc cucgcccuac      120

uccucuaccu acaccacgcc aaaugguccc aagccgcacc cauggccgaa ggcggcggcc      180

aaaaccacca cgaagucguc aaauucaugg acgucuacca acgcucauac ugccacccca      240

ucgaaacccu cgucgacauc uuccaagaau accccgacga aauagaauac aucuucaaac      300

ccucaugcgu cccccucaug cgcugcggcg gcugcugcaa cgacgaagga cucgaaugcg      360

uacccaccga agaaucaaac aucacaaugc aaaucaugcg caucaaaccc caccaaggcc      420

aacacaucgg cgaaaugucc uuccuccaac acaacaaaug cgaaugccgc cccaaaaaag      480

accgagcacg acaagaaaaa aaauccgucc gaggcaaagg caaaggccaa aaacgaaaaa      540

gaaaaaaauc ccgcuacaaa uccugguccg uauacgucgg cgcccgaugc ugccucaugc      600

cauggucccu ccccggcccc cacccaugcg gccccugcuc cgaacgccgc aaacaccucu      660

ucguccaaga cccccaaacc ugcaaaugcu ccugcaaaaa caccgacucc agaugcaaag      720

cccgccaacu cgaacucaac gaacgcaccu gccgcugcga caaaccccga cgcuaaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  7238
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt11)

<400>  7238
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uccccccucc uccgccgccu ccuccucgca gcccuacucc      120

aacuagcccc cgcacaagcc cccgucuccc aacccgacgc ccccggccac caacgcaaag      180

uagucuccug gauagacguc uacacccgcg ccaccugcca accccgcgaa gucguagucc      240

cccucacagu cgaacucaug ggcacagucg ccaaacaacu cguacccuca ugcgucaccg      300

uccaaagaug cggcggcugc ugccccgacg acggccucga augcgucccc accggccaac      360

accaaguccg caugcaaaua cucaugaucc gauacccauc aucccaacua ggagaaaugu      420

cacucgaaga acacucucaa ugcgaaugca gacccaaaaa aaaagacuca gccguaaaac      480

cagaccgcgc cgcaacaccc caccaccgcc cccaaccacg aucagucccc ggcugggacu      540

ccgcccccgg cgcccccucc cccgccgaca ucacccaccc cacccccgcc cccggcccau      600

ccgcccacgc cgcccccucc accaccucug cccuaacccc cggccccgcc gccgccgccg      660

cagacgccgc cgccucaucc gucgccaaag gcggcgccua aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  7239
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt11)

<400>  7239
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuccuag gcuucuucag cguugccugc ucccuacugg      120

ccgccgcccu ccucccuggc ccccgcgaag cucccgcagc cgcagcagcc uuugaaucag      180

gucucgaccu uagcgacgca gaacccgacg ccggagaagc uaccgccuac gcgagcaaag      240

accucgaaga acaacugcga uccgucuccu ccgucgacga acucaugacu guacucuacc      300

ccgaauacug gaaaauguac aaaugccaac uccggaaagg aggcuggcaa cacaacagag      360

aacaagccaa ccucaacucc cgaaccgaag aaacuaucaa auucgccgca gcccacuaca      420

acaccgaaau acucaaauca aucgacaacg aauggagaaa aacccaaugc augccccgag      480

aagucugcau cgacgucggc aaagaguucg gagucgccac caacacauuc uucaaaccac      540

cuuguguauc cgucuaccga ugcggagguu gcugcaacuc cgaaggccua caaugcauga      600

acaccuccac cucauaccuc ucaaaaacac ucuucgaaau caccgucccc cuaagccaag      660

gcccgaaacc agucaccauu uccuucgcaa accauacauc augccgaugu augucaaaac      720

ucgacgucua ccgccaaguc cacuccauaa uccgacgcuc acucccagcc acccuccccc      780

aaugccaagc agcaaacaaa accugcccaa ccaacuacau guggaacaac cacaucugcc      840

gcugccucgc acaagaagac uucauguuca gcuccgacgc cggcgacgac uccaccgacg      900

gcuuccacga caucugcggc cccaacaaag aacucgacga agaaacaugc caaugcguuu      960

gucgcgccgg ccuccgccca gccuccugcg gaccacacaa agaacucgac agaaacuccu     1020

gccaaugcgu uugcaaaaac aaacuauucc caucccaaug cggagccaac cgcgaguucg     1080

acgaaaauac cugccaaugc guaugcaaac gaaccugccc ccgaaaccaa ccccuaaacc     1140

ccggcaaaug cgcuugcgaa ugcaccgaau ccccgcaaaa augccuccuc aaaggaaaga     1200

aauuccacca ccaaaccugc uccugcuacc gccgacccug caccaaccgu caaaaagcgu     1260

gcgaacccgg auucuccuac uccgaagaag ucugccgcug cguccccagc uacuggaaac     1320

gcccccaaau guccuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  7240
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt11)

<400>  7240
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uaccgagaau gggucgucgu caacguauuc augaugcucu      120

acguacaacu cguccaaggc agcagcaacg aacacggccc cgucaagaga uccagccaaa      180

gcacccuaga acgauccgaa caacaaauac gcgcagccuc aagccucgaa gaguuacuac      240

gaaucaccca cucagaagac uggaagcucu ggcgaugccg ccuccgccuc aaguccuuca      300

ccuccaugga cagcagauca gccucccacc gcucaacccg uuucgccgcc accuucuacg      360

acaucgaaac ccucaaaguc aucgacgagg aauggcaacg aacacaaugc ucucccagag      420

aaaccugcgu agaagucgcc uccgaacuug guaaaucaac caacacuuuc uucaaaccac      480

ccugcgucaa cgucuuccgc ugcggaggcu gcugcaacga agagucccuc auaugcauga      540

acacauccac cuccuacauc uccaaacaac ucuucgaaau auccguaccc cuaaccuccg      600

ucccagaacu uguacccguc aaagucgcca accacaccgg cugcaaaugc cuccccacag      660

caccccgcca ccccuacucc auaauccgcc gaucgauaca aauaccggaa gaagaccgcu      720

gcucacacuc aaagaaacuc ugccccauag acaugcucug ggacuccaac aaaugcaaau      780

gcguccucca ggaagaaaac ccccuagccg gcacagaaga ccacucccac cuccaagaac      840

cagcccucug cggcccccau augauguucg acgaagaccg cugcgaaugc guaugcaaaa      900

cccccugccc caaagaccuc auccaacacc ccaaaaacug cucaugcuuc gaaugcaaag      960

aaucacucga aaccugcugc caaaaacaca aacucuucca ccccgacaca ugcucaugcg     1020

aagaccgaug ccccuuccac acccgccccu gcgccuccgg caaaaccgcc ugcgccaaac     1080

acugccgauu cccaaaagaa aaacgcgccg cccaaggccc ccacucacgc aaaaauccau     1140

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  7241
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt12)

<400>  7241
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gauuccgacg aaaccggcuu ugaacacuca ggauuauggg      120

uaucaguauu agcaggacua cuacuaggag caugccaagc acacccaaua ccagacucau      180

caccauuauu acaauucgga ggacaaguaa gacaaagaua ccuauacaca gacgacgcuc      240

aacaaacaga agcacauuua gaaauaagag aagacggaac aguaggaggc gcagccgacc      300

aaucaccaga aucuuuacua caauuaaaag cacuaaaacc aggcguaaua caaauauuag      360

gaguaaaaac aucaagauuc uuaugccaaa gaccagaugg agcacuauac ggaucacuac      420

acuuugaccc agaagcaugc ucauucagag aauuacuauu agaagacgga uauaacguau      480

accaaucaga agcacaugga cuaccccuac accuaccagg aaacaaauca ccacaucgag      540

acccagcccc aagaggcccc gcaagauucc uaccacuacc aggacuacca ccagcacuac      600

cagaaccacc aggaauauua gcaccacaac caccagaugu aggauccucc gacccauuau      660

caaugguagg accaucacaa ggaagaucuc caucauacgc aucauaagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  7242
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt12)

<400>  7242
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauucauucc caccucuauu acuacuauua uuuuggggug      120

uuguauccca cucauuucca gcuacauuag aaacacaaga acaagacgua gaucuagucc      180

aaaaauaucu agaaaaauac uacaaccuaa aaaacgacgg acgccaagua gaaaaaagaa      240

gaaacagugg accaguagua gaaaaacuaa aacaaaugca agaauuuuuu ggacuaaaag      300

ucacaggaaa accugaugcc gaaacuuuaa aaguaaugaa acaaccaaga ugcggcguac      360

cugacguagc acaauucguc uuaacagaag gaaacccaag augggaacaa acgcacuuaa      420

cauaucgaau cgaaaauuac acaccagacc uaccaagagc agacguagau cacgcaauag      480

aaaaagccuu ccaacuaugg ucaaauguaa caccccuaac auucacaaaa guaucagaag      540

gacaagcaga uauaaugauc ucauucguaa gaggggauca cagagauaac ucacccuucg      600

auggcccagg aggaaaccua gcacacgcau uccaaccugg accaggaaua gguggugaug      660

cacauuucga cgaagacgaa agauggacaa acaacuucag agaauauaac cuacacagag      720

uagcagcuca cgaacuaggu cauucauuag gacuaaguca uucaacagau auaggagcac      780

uaauguaccc aucauacacu uuuagcggag acguacaacu agcacaagac gacauagaug      840

gaauacaagc aauauacgga agaucacaaa accccguaca accaauagga ccacaaacac      900

caaaagcaug ugacucaaaa cucaccuucg acgcaauaac aaccauaaga ggagaaguua      960

uguucuuuaa agacagauuc uacaugagaa caaaucccuu uuacccagaa guagaauuaa     1020

acuucaucuc aguauuuugg ccccaacuac caaauggucu agaagcagcc uacgaauuug     1080

cugauagaga ugaaguaaga uucuucaaag gaaacaaaua uugggccguc caaggacaaa     1140

acguauuaca cggauaucca aaagauaucu acuccucauu cggcuuucca agaacaguaa     1200

aacauauuga ugcagcacua uccgaagaaa acacaggaaa aacauacuuc uuuguagcca     1260

acaaauacug gagauaugau gaauacaaaa gaucgaugga cccaggauac cccaaaauga     1320

uagcacacga cuuuccagga auaggacaca aaguagaugc aguauucaug aaagacggau     1380

ucuucuacuu cuuccacggc accagacaau acaaauuuga ccccaaaaca aaacgcaucc     1440

uaacauuaca aaaagcaaau ucaugguuua acuguagaaa aaacuaagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  7243
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt12)

<400>  7243
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacucauucc caccacuauu auuacuacua uucuggggag      120

uaguaucaca cuccuucgua uuaacugaag gaaauccucg augggaacaa acccaccuca      180

cauauagaau agaaaacuac acaccagacc uaccuagagc agacguagac cacgcaauag      240

aaaaagccuu ccaauuaugg uccaacguca caccauuaac uuucacuaaa gucucagaag      300

gacaagcaga uauaaugaua uccuuuguca gaggagauca cagagacaac ucaccauuug      360

acggaccagg aggaaaucua gcacacgcau uccaacccgg acccggaaua gguggagacg      420

cacacuucga ugaagaugaa agauggacaa acaauuucag agaauacaau uuacacagag      480

uagcagcaca cgaacucgga cacuccuuag gacucuccca uucaaccgac auaggagcau      540

uaauguaccc aucauacaca uucucaggag acguccaacu agcacaagac gauaucgacg      600

gcauacaagc uauauacgga agaucacaaa acccaguaca accaaucgga ccacaaacac      660

caaaagccug ugacucaaaa uuaacuuuug augcaaucac aacuauacga ggcgaaguaa      720

uguuuuucaa agacagauuc uacaugagaa caaaccccuu uuacccugaa guagaacuaa      780

acuucauauc uguuuucugg ccacaacuac caaacggauu agaagcagca uacgaauuug      840

ccgacagaga cgaaguuaga uucuucaaag gaaacaaaua cugggcaguu caaggacaaa      900

acgucuuaca cggauaucca aaagauauau acuccucauu cggauuccca agaaccguaa      960

aacacaucga ugccgcauua ucagaagaaa auacaggcaa aacauacuuc uuuguugcaa     1020

acaaauauug gagauacgac gaauacaaac gcucuaugga cccaggcuau ccaaaaauga     1080

uugcacacga uuucccagga auaggacaca aaguagaugc aguauucaug aaagacggau     1140

ucuuuuauuu cuuccacgga acaagacaau acaaauucga uccaaaaaca aaaagaaucc     1200

uaaccuuaca aaaagccaac ucaugguuca auugcagaaa aaauuaagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  7244
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt12)

<400>  7244
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaaaaaca uacugaaaau cuuaauggac uccuacucca      120

aagaaucaaa aauccaaaca guaagacgug uaacaucagu aucacuccug gcaguauacc      180

uuacaaugaa cacuucuucc uuaguauuag ccaaaccaau agagaauacu aaugacacau      240

caaucaaaaa uguagaaaaa uuacgaaaug cacccaacga agaaaacagc aagaaaguag      300

aagauuccaa aaacgacaaa guagaacaug uuaaaaacau agaagaagcu aaaguagaac      360

aaguugcucc ggaagugaaa ucaaaaucaa cguugagaag ugcaaguaua gcaaacacca      420

acuccgaaaa auaugacuuc gaauacuuaa auggacuauc guacacagaa uuaacaaauu      480

uaauuaaaaa cauaaaaugg aaucaaauaa auggucuguu caacuauagu accggcuccc      540

aaaaauucuu cggagauaaa aaucguguuc aagcuauaau aaaugcacua caagaaucug      600

guagaacaua uaccgcuaac gauaugaaag gaauagagac uuuuacggaa guccuaagag      660

ccggauucua cuuaggauac uauaacgaug guuuaaguua uuuaaaugac agaaauuuuc      720

aagacaaaug cauaccggca augauagcaa uacagaaaaa cccuaacuuu aagcuaggaa      780

cagcugucca agacgaagua auuacaucac uagguaaacu uaucggaaau gcaagcgcaa      840

acgcagaagu cguaaauaau ugugucccag uacuaaaaca auuuagagaa aauuuaaacc      900

aauaugcucc agacuaugua aaaggaacag caguaaauga acuuauaaaa gguauagagu      960

ucgacuucuc aggagcagca uaugaaaaag acguaaaaac aaugccaugg uauggaaaaa     1020

ucgauccauu uauaaaugaa uugaaggcau uaggccuaua uggaaauaua accagcgcga     1080

cagaaugggc aucagacguc ggaauuuacu accuuaguaa auucggacua uauagcacaa     1140

auagaaauga cauaguacaa agccucgaaa aagcgguaga uauguacaaa uauggaaaaa     1200

uagcuuucgu agccauggaa cgaauaacau gggacuauga ugguauaggu ucaaacggaa     1260

agaaagucga ccacgauaaa uuccuagacg augcugaaaa acacuacuua ccaaaaaccu     1320

acacguucga uaauggaacu uuuauaauac gugcuggaga caaaguuuca gaagagaaaa     1380

ucaaaagauu auauugggcu ucgcgagaag uaaaaucuca auuccaccga guaguaggaa     1440

acgauaaagc auuagaaguu ggaaaugcgg acgauguauu aacaaugaaa auuuucaacu     1500

cacccgaaga auauaaauuu aauacuaaca uuaacggugu aagcacagau aacggagguu     1560

uauacauaga accucgagga acauuuuaua cguaugaacg aacaccacaa caaagcauau     1620

uuucguuaga agaacuauuu agacaugaau auacacauua ccuacaagca cgauacuuag     1680

uagauggauu auggggucaa ggacccuuuu acgaaaagaa ucgccucaca ugguucgaug     1740

aaggcaccgc ugaguucuuu gcuggcucga cgagaacaag uggagugcuc ccaagaaaaa     1800

guaucuuagg auaccuugca aaagauaagg uugaccaucg uuauucacua aagaaaacuu     1860

uaaauucagg uuacgacgac agugauugga uguuuuacaa uuacggauuu gcaguagcac     1920

auuaucucua cgaaaaagac augcccaccu uuauaaaaau gaauaaagca auuuuaaaca     1980

ccgauguaaa auccuacgau gaaauaauua agaaacugag ugaugacgcc aacaaaaaua     2040

ccgaauauca aaaucacauc caagaauuag ccgacaaaua ccaaggagca gguauaccgc     2100

uagugaguga ugacuaucuc aaagaccacg gcuauaagaa agcaucugaa guuuacuccg     2160

aaauuagcaa agcggcauca cucaccaaua cuagcgucac cgcagaaaaa ucccaauacu     2220

uuaauacauu uacucuucga ggcacauaca caggagaaac gagcaaagga gaauuuaaag     2280

acugggacga aaugaguaag aaacucgaug gaacauuaga aucauuagcc aaaaacuccu     2340

ggaguggcua caaaacacuu acugcauacu ucacaaauua uagaguaaca agugauaaua     2400

aaguacaaua ugauguaguc uuucacggug uauuaacaga uaaugcagau auaucaaaca     2460

acaaagcacc aauagcaaaa guaacuggac caucaacagg ggcugucggg agaaauauug     2520

aguucucagg caaagauuca aaagacgaag augguaaaau uguuucguac gauugggauu     2580

uuggcgacgg agcaacaagu cgugguaaaa acaguguaca ugccuacaag aaagccggaa     2640

ccuacaaugu aacauuaaaa guaaccgacg acaaaggagc aaccgccaca gaaaguuuua     2700

cuauagaaau uaaaaaugaa gacacaacaa cccccauaac uaaagaaaug gaaccaaacg     2760

acgacauaaa agaagcaaau ggaccgaucg uagaaggagu uaccguuaaa ggagacuuaa     2820

acggcucaga ugacgcagau acuuuuuacu ucgaugucaa agaagacgga gaugucacaa     2880

uagaauuacc cuacagugga ucuucaaacu uuaccuggcu agucuauaaa gaaggagaug     2940

accaaaauca uauagcaagc ggaauagaua aaaacaacag caaaguaggc acauucaaaa     3000

guacaaaagg caggcauuac guauuuauau acaaacacga uucugccuca aacauuucuu     3060

acaguuuaaa uauuaaaggu cuaggaaaug aaaaacuaaa agaaaaagaa aacaacgacu     3120

caucugacaa agcaacagua auaccuaacu ucaacacaac aaugcaagga ucauuacuag     3180

gagaugacag uagagauuac uauucauuug aaguaaaaga agaaggugaa guaaauaucg     3240

agcuagauaa gaaagacgaa uuuggaguga cauggacccu ucacccagaa ucaaauauaa     3300

acgaucgaau aacauaugga caagucgaug gcaacaaagu aucaaauaaa guuaaauuaa     3360

gaccaggaaa auauuaucuc cuuguauaca aguauucagg caguggaaac uaugaauuga     3420

gaguaaacaa augaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  7245
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt12)

<400>  7245
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguca cauuuauuuc acuacuguuu uuauucucau      120

cagcauauag uauagcaaau acaaacagug aaaaauacga uuucgaauau cucaacggau      180

ugucauauac agaacuuacc aaccuuauua aaaauauaaa auggaaccaa auaaaugguc      240

uauuuaauua caguacgggu ucgcagaaau ucuuuggaga uaaaaaccgu guacaggcca      300

uaauaaacgc acuacaggaa uccggacgca ccuauacggc uaaugauaug aaaggaauag      360

aaacuuuuac ugaaguacua agagccggau uuuaucucgg auauuacaau gauggauuga      420

guuaccuaaa cgauaggaac uuucaagaca aauguauucc agcaaugaua gcaauacaga      480

aaaaccccaa cuucaaauua ggcacagccg uacaagacga aguuauaacu ucauuaggaa      540

aauuaaucgg uaacgcaagc gcaaacgccg aaguaguaaa uaauugugua ccaguacuaa      600

aacaauucag agaaaaccuc aaccaauacg cacccgauua cguaaaaggg acagcaguaa      660

augaauuaau aaaagguauc gaauuugacu ucuccggagc agcuuaugaa aaagacguua      720

aaacuaugcc cugguacgga aaaauagauc cuuuuauaaa ugaacucaaa gcauuaggac      780

ucuaugggaa uauaacaucg gcuacugaau gggccagcga cguaggaaua uauuauuuau      840

caaaauuugg gcuauacuca acgaacagga augauauagu acaaucgcua gaaaaagccg      900

uagacaugua uaaauauggu aaaauugcau ucgucgcaau ggaaagaauu acaugggauu      960

augacggaau aggguccaac ggcaagaaag uagaucacga uaaauuuuua gacgacgcug     1020

aaaaacauua uuuaccaaaa acauauacuu uugacaacgg uacauucauc auuagggcag     1080

gagauaaagu uuccgaagag aaaauaaaaa gauuauacug ggcaagucga gaaguaaaau     1140

cacaauucca cagaguagua ggcaacgaua aagccuuaga agucgguaau gcugacgaug     1200

uauuaaccau gaaaauauuc aacaguccug aagaauacaa auuuaauacc aauauaaaug     1260

gaguaaguac cgauaauggc ggacuauaca uagaaccucg aggaaccuuc uacacguacg     1320

aacgaacucc gcaacaauca auauuuaguc uagaagaacu auuucggcau gaauauacgc     1380

acuacuuaca agcuagauau cuuguagacg gauuaugggg gcaaggaccc uucuaugaaa     1440

agaaucgauu aacaugguuu gacgaaggaa cugcugaauu uuucgcaggu ucaacaagaa     1500

cgucaggagu acuaccaagg aaaaguauac uaggcuaccu ugcaaaagau aaaguugauc     1560

aucgauauuc acuaaagaaa acacuaaaua gugguuauga cgacucagau uggauguucu     1620

auaacuaugg uuuugcagug gcacauuauc uauaugaaaa agauaugcca accuucauaa     1680

aaaugaacaa agccauauua aauacugacg ucaaaucaua cgacgaaaua auuaagaaau     1740

uaucagacga ugcaaacaaa aauacagaau aucaaaacca uauacaagaa uuagcagaua     1800

aauaucaagg ugcagguauu ccauuaguau cggaugauua uuuaaaagau cauggauaca     1860

agaaagccag cgaaguauac ucugaaauua gcaaagcagc gucacucacg aauacaucug     1920

uuacugcaga aaaaucacaa uauuuuaaua cauuuacacu gcguggaacc uauaccggag     1980

aaacaucaaa aggugaauuu aaagacuggg acgaaauguc aaagaaacua gauggaaccc     2040

ucgaaaguuu agccaaaaau ucauggagug gauauaaaac ucuuacugca uacuucacua     2100

auuacagagu aacaucagac aacaaaguac aauacgacgu aguauuucau ggcgucuuga     2160

cagauaaugc cgacauuuca aauaacaaag ccccaauagc uaaagugaca ggaccaucaa     2220

caggcgcagu cggaagaaau auugaguucu cagggaaaga uaguaaagac gaagauggaa     2280

aaauaguuag cuaugacugg gacuucggag auggagcaac aucucgaggu aaaaacuccg     2340

uacacgcaua uaagaaagcu ggaaccuaua acguuacauu aaaaguaacu gaugauaaag     2400

gagcaacugc aacagaaagu uuuacuauag aaaucaaaaa cgaagauacc acaacaccaa     2460

uaacaaaaga aauggaacca aacgacgaca uaaaagaagc gaauggaccc auaguagaag     2520

gagucacugu uaaaggagac uuaaauggga gcgacgaugc cgacacuuuu uauuucgacg     2580

uuaaagaaga uggagacgua acuauagaau uacccuacuc uggaaguagu aauuuuaccu     2640

ggcuaguaua caaagaaggc gaugaucaaa accauauagc gucaggaaua gauaaaaaua     2700

auucaaaagu gggcacuuuc aaaagcacaa aaggaagaca uuacguauuc auuuauaaac     2760

acgauucagc aucaaacaua ucauacucgc uuaauauaaa aggacuagga aacgaaaaac     2820

uuaaagaaaa agaaaacaau gacucaucag acaaagccac aguaauucca aauuuuaaca     2880

cuacuaugca aggaagccuu uuaggagaug auaguagaga uuauuauuca uucgaaguaa     2940

aagaagaagg agaaguuaau aucgaacuag auaagaaaga ugaguucggu guaacgugga     3000

cauuacaccc ugaauccaau auuaacgaca gaaucaccua uggacaaguu gacggaaaua     3060

aagucagcaa caaaguuaaa uuaagacccg gaaaauauua ccuccuaguu uauaaauaua     3120

gcggaucagg aaacuacgaa uuacgaguaa auaaaugagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  7246
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt12)

<400>  7246
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguaa cauucauauc auuacuuuuc cuauuuucau      120

cagcauacag uaugaagaaa aauauauuaa aaauauuaau ggacagcuau agcaaagaau      180

caaaaauaca aacaguuaga agaguaacua gcguuagcuu auuagccgua uacuuaacaa      240

ugaauacaag uagccuagua uuagcaaaac cgauagaaaa uacaaacgac acgagcauca      300

aaaacguuga aaaacuaaga aaugccccca acgaagaaaa caguaagaaa gucgaagaca      360

guaaaaauga uaaaguagaa caugugaaaa acauagaaga agccaaagua gaacaaguag      420

ccccugaagu uaaaagcaaa ucaacgcuac gcagcgccag uaggagaaga agaaaaagaa      480

uagcaaauac uaacucagaa aaauaugacu ucgaauacuu aaauggacua aguuacacag      540

aacuuaccaa ucuuaucaaa aacauaaaau ggaaucaaau aaauggacua uucaauuauu      600

ccacuggguc acaaaaauuu uucggagaua aaaauagagu gcaggcuaua auuaacgcac      660

uacaagaauc aggaagaacc uacacagcaa acgauaugaa agggauagaa acuuucacug      720

aaguacugcg agcgggauuc uauuuggggu acuauaacga cgguuuauca uacuuaaacg      780

acagaaauuu ucaagacaaa uguauaccag caaugauagc aauacagaaa aauccuaauu      840

uuaaacuagg gaccgcagua caagacgaag ugauaacauc acucgguaaa cucauaggaa      900

augcuucagc uaaugcggaa guaguaaaua auugcguacc aguuuuaaaa caauucagag      960

aaaaccucaa ccaauaugca cccgacuaug uaaaaggaac ugcaguuaac gaacuuauca     1020

aaggaaucga auuugauuuu agcggagccg cguacgaaaa agacgugaaa acaaugccuu     1080

gguauggaaa aauagaccca uucauuaacg aauuaaaagc cuuaggccug uacgguaaua     1140

uaacuucagc cacagaaugg gcaagugacg uuggcauaua cuauuugucg aaauuuggau     1200

uguauucaac aaaccguaac gacauaguuc aaagccugga aaaagcagua gauauguaca     1260

aauauggaaa aauagccuuu guagcaaugg aaaggauuac augggauuau gacggaauag     1320

gcucaaaugg uaagaaagua gaucaugaua aguuucuaga cgaugcagaa aaacacuauc     1380

uuccaaagac auacaccuuc gacaauggaa cuuuuauuau aagggcaggc gacaaaguau     1440

ccgaagagaa aauaaaacgu uuauacuggg caucacggga aguaaaaagc caauuucaua     1500

gaguaguagg aaacgacaaa gcauuagaag uaggaaacgc agaugacgua cucacaauga     1560

aaauauucaa uucuccugaa gaauauaaau ucaauacaaa uauaaaugga gucaguacag     1620

acaauggagg acuauacaua gaaccuagag ggacauuuua uacuuacgaa agaacacccc     1680

aacaauccau auuuucccua gaagaauugu uccgacauga auacacacau uauuuacaag     1740

cccgauacuu aguagacgga uuauggggac aagguccauu cuacgagaaa aacagauuga     1800

caugguucga cgaaggaaca gcagaauuuu ucgccggauc aacuagaacc uccgguguau     1860

uaccaagaaa auccauccuu ggguacuuag caaaagauaa aguagaucau cguuauucgu     1920

uaaagaaaac auuaaauagc ggcuacgaug auucagauug gauguuuuau aauuauggcu     1980

uugcuguagc acauuaucua uacgaaaaag auaugccaac uuucaucaaa augaacaaag     2040

cgaucuuaaa uacagacguu aaaucauaug acgaaaucau aaagaaauua ucagaugaug     2100

caaauaaaaa cacagaauau caaaaccaca uacaagaacu agcugauaaa uaucagggug     2160

caggaauccc acucguaucg gacgauuacc uaaaagacca uggauauaag aaagcaagcg     2220

aaguauacuc agaaauuagu aaagcugcau cucuuacaaa uacaagcgua acggcagaga     2280

aaagccaaua uuucaacacg uucacacuac gcggaacaua uacuggagaa acaaguaaag     2340

gagaguucaa agauugggac gaaaugucaa agaaauuaga ugguacuuua gaaucauuag     2400

ccaaaaauag cugguccggg uacaaaacac uuaccgcaua cuuuacaaau uauagaguca     2460

caagcgauaa uaaaguucaa uacgaugucg ucuuucacgg aguacuaaca gacaacgcgg     2520

auauaagcaa uaauaaagca ccaauagcaa aaguaacagg accaucaacc ggagcuguug     2580

gaagaaacau ugaguucuca ggaaaagacu caaaagacga agauggcaaa auaguaagcu     2640

augauuggga uuuuggagac ggcgcaacau ccagaggcaa aaauagcguc caugccuaua     2700

agaaagcagg aacauacaac guaacauuaa aaguaacaga cgacaaagga gccaccgcca     2760

cugaaaguuu uacuaucgaa aucaaaaaug aagauacaac caccccaaua accaaagaaa     2820

uggaaccuaa ugaugacaua aaagaagcua augggccaau uguagaagga gucacaguca     2880

aaggcgacuu aaacgggagc gacgacgcug auaccuucua cuuugacgua aaagaagaug     2940

gagauguaac aauagaacua ccauauucag guucauccaa uuuuacaugg cuaguguaca     3000

aagaagguga cgaccaaaac cauauagcca guggaauuga caaaaacaau ucuaaagugg     3060

ggacuuuuaa aagcacaaaa gguagacauu auguauuuau auacaaacau gauagugcaa     3120

gcaacauauc auacucucua aauaucaaag gcuuaggaaa cgaaaagcua aaggaaaagg     3180

aaaauaacga uuccucagau aaagcaacug ugaucccaaa uuucaacacu acuaugcaag     3240

gcagccuucu cggugaugau agccgagauu acuacuccuu ugaagucaaa gaagaaggug     3300

aagucaacau agaauuggau aagaaagaug aguucggcgu cacauggaca cugcauccag     3360

aaucaaacau aaacgauaga aucaccuacg gacaagucga cggaaauaaa guaagcaaua     3420

aagucaaauu aagaccagga aaauacuacc uucuaguaua uaaauacucu ggaaguggaa     3480

auuacgaauu acgaguuaau aaauaaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  7247
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt12)

<400>  7247
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuuuuga agauaauacu aaauagagga aaaacaauga      120

aaagaaaaug ccuauccaaa cgauuaaugc uggccauaac uauggcaaca auauuuacag      180

uaaacaguac auuaccuaua uaugcagcug uagauaaaaa caacgcuaca gcugccgucc      240

agaacgaauc uaaaagguac accguaucuu aucuaaaaac ucuaaacuac uaugacuuag      300

uagauuugcu aguaaaaaca gaaauagaga aucuaccaga cuuauuucaa uauucaagcg      360

augccaaaga guucuaugga aauaaaacca gaaugaguuu uauaauggau gaaauaggua      420

gacgagcacc acaauacaca gaaaucgacc auaagggaau accgacacuu guagaagugg      480

uaagagcagg auucuauuua ggauuccaua auaaagaauu aaacgagaua aacaaacgau      540

ccuuuaaaga aagagucaua ccaagcauau uagcaaucca gaaaaaucca aauuucaagc      600

uaggaacaga aguacaagau aaaauuguaa gcgcaacagg auuacucgca gggaacgaaa      660

cagcaccccc agaagucgug aacaacuuca ccccaauacu ccaagacugu aucaaaaaua      720

uagauagaua cgcacuagau gaccuaaaaa guaaagcccu uuucaacgua cuugcagcac      780

caaccuauga uauaacugaa uaccuacgag caacaaaaga gaaaccagaa aacacacccu      840

gguacgggaa aauagacggc uuuauaaaug aguuaaagaa auuagccuua uaugguaaaa      900

uaaaugauaa uaauucaugg auaauagaca acggcauuua ucauaucgca ccucugggaa      960

aauuacacag uaauaacaaa auagguauug aaacacuaac agaaguaaug aaaguuuauc     1020

cauaucuaag caugcaacac cuccaaucag cagaucaaau aaaacgacac uacgacucua     1080

aggacgcaga agggaacaaa auaccacuag acaaauucaa gaaagaagga aaagaaaaau     1140

acugcccaaa aacauauaca uucgacgaug gcaaaguaau uaucaaagcu ggcgcaaggg     1200

uagaggaaga aaaaguaaaa cgucuauauu gggcuucaaa agaaguaaau ucacaauucu     1260

uucgaguuua cggaauugau aaaccauuag aagaaggaaa cccagaugac auucuaacua     1320

ugguuauaua uaauucacca gaagaauaua aacuaaacuc aguauuauac ggauaugaua     1380

ccaacaacgg ugggauguac auagaacccg aaggaacauu cuuuacuuau gaacgcgaag     1440

cacaagaaag cacuuacacg uuagaagaac uauuccgaca cgaauauaca cauuacuuac     1500

aaggacgcua ugcaguucca ggacaauggg gacgaacaaa auuauaugau aacgacagac     1560

uaacauggua cgaagaagga ggagcagaau uauuugcugg uaguacucga acaaguggaa     1620

uacuacccag aaaaagcauu guaagcaaca uacauaauac aacacgcaac aacagauaua     1680

aacuaucaga uacuguacau uccaaauaug gcgccagcuu ugaguucuac aacuacgcau     1740

gcauguucau ggacuacaug uacaauaaag acauggguau acucaacaaa cuaaacgauc     1800

ucgccaaaaa uaacgacguu gacggauaug auaauuacau uagagaccuc aguucaaauu     1860

augcauuaaa ugacaaauac caagaucaca ugcaagaaag aauagauaac uaugaaaacu     1920

uaacaguacc auucguugca gacgauuacu uaguaagaca cgcauauaaa aacccuaacg     1980

aaauauauuc ggaaauuuca gaaguugcaa aauuaaaaga ugcaaaaucu gaaguaaaga     2040

aaagucaaua uuuuucgacc uucacauuac guggaagcua uacaggaggu gcauccaaag     2100

gaaaacucga agaucaaaaa gcaaugaaca aauuuauaga cgacucuuua aagaaacuag     2160

acacauauuc guggagcggg uacaaaacau uaacggcaua cuucacgaau uauaaaguug     2220

acaguucaaa uagagucaca uaugauguag ucuuucacgg auaccuaccu aacgaaggag     2280

acaguaaaaa uagucucccc uaugggaaaa uaaauggcac auacaaaggu accgagaaag     2340

agaaaauaaa auuuuccucg gaaggcucau ucgacccuga uggaaaaaua guaucauacg     2400

aaugggacuu cggagaugga aauaaaagua acgaagaaaa uccagaacac ucauacgaua     2460

aaguagggac cuauaccgua aaacucaaag uaacagauga caaaggcgaa agcucaguuu     2520

caacaacaac ugcagaaauu aaagauuuau cagaaaauaa auuaccagua auauauaugc     2580

auguaccaaa aaguggggca cuaaaucaaa aaguaguguu cuaugggaaa ggaacauaug     2640

auccagacgg aucaauugca gguuaccaau gggauuuugg agaugguuca gauuucucaa     2700

gugaacaaaa uccaucccac guuuauacaa agaaaggaga auacacagua acuuuacgag     2760

uaauggacag uucagggcaa augucggaga aaacaaugaa aauuaaaaua acagauccag     2820

uauacccaau aggaacagaa aaagaaccua auaauucaaa agaaacugca ucagggccaa     2880

uaguacccgg aauacccgua uccgguacua uagaaaacac aucagaucaa gacuacuucu     2940

auuuugaugu uauaacgcca ggagaaguaa aaauagauau caacaagcua ggauauggag     3000

gagcaacgug gguaguguau gaugaaaaua auaacgcagu uucauaugca acugacgaug     3060

gacaaaaccu cuccggaaaa uucaaagcag auaaaccagg aagguauuac auacaccugu     3120

acauguucaa uggcucuuau augccguauc guauaaauau cgaaggguca guaggaagau     3180

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  7248
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt12)

<400>  7248
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacgaaaau gcuuaucaaa aagauuaaug uuagcaauaa      120

caauggccac uauauucacu gucaauucaa cccuuccaau auacgccgca guagacaaga      180

acaaugcuac agcagcagua caaaaugaaa guaagagaua cacaguaucg uaucuaaaaa      240

cucuaaacua uuaugaccuc guggaccugc uaguaaaaac agaaauagaa aauuuaccug      300

auuuauucca guauucauca gaugcaaaag aguucuaugg caauaagaca agaauguccu      360

ucauaaugga ugaaauaggc agacgagcac cacaauacac ugaaauugac cacaagggaa      420

uaccaacccu agucgaagua gucagagcag gauucuaccu aggcuuccau aauaaggaac      480

uaaacgaaau aaacaaaaga aguuucaaag aaagagugau accaucaaua uuagcaauac      540

agaaaaaucc caacuuuaaa cuuggaacag aaguacaaga caaaauugug agcgcaaccg      600

gauuacuagc agggaacgaa acagcaccuc ccgaaguagu gaauaauuuu acgccaauau      660

uacaagauug cauuaaaaac auagacagau augcacuaga ugauuuaaaa ucuaaagcau      720

uauuuaacgu acuagcagcu cccacauaug auauaacaga auaccucaga gccaccaaag      780

aaaaaccuga aaauacacca ugguauggaa aaaucgacgg cuuuaucaau gaacuuaaaa      840

agcuagcacu auauggaaaa aucaacgaua acaacucaug gaucauagau aauggaauau      900

accauauagc acccuuaggc aaacuucacu caaacaauaa aaucggcaua gaaacauuaa      960

cggaaguaau gaaaguauac ccuuaucuau cuaugcaaca uuuacaauca gcagaucaaa     1020

uaaaacgcca cuacgauagu aaagaugcag aaggaaacaa aauaccccuc gacaaguuca     1080

agaaagaagg aaaagaaaaa uauuguccaa aaacauauac guucgacgau ggaaaaguaa     1140

uaauaaaagc aggagcaaga guagaagagg aaaaaguaaa aagauuauac ugggcgucaa     1200

aagaaguaaa cucacaauuc uucagaguuu auggaauaga caaaccauua gaggaaggaa     1260

aucccgauga cauucuuacc auggugaucu acaacagucc ugaagaauau aaacuaaauu     1320

cuguccucua cggauaugau acaaacaacg gaggcaugua uaucgaacca gaaggaaccu     1380

uuuucacaua ugagagagaa gcucaagaau caaccuacac ccucgaggaa cuauucagac     1440

acgaauauac gcacuaucua caaggcaggu acgcaguacc cggacaaugg ggccguacaa     1500

aacuauauga caacgacaga cuaacuuggu acgaagaagg aggggcugaa uuauuugccg     1560

gaucaacaag aaccucaggg auucuuccac gaaaaucgau aguuucgaau auacacaaua     1620

caaccagaaa caauagauau aaauuaucag auacagugca uuccaaauau ggggcuucau     1680

ucgaguuuua caauuaugcu ugcauguuca uggauuauau guauaacaaa gacaugggaa     1740

uacucaacaa acuaaaugac cucgcuaaaa acaaugacgu agauggauac gacaauuaca     1800

uacgcgauuu aagcuccaac uaugcauuaa acgacaaaua ucaagaucau augcaagaaa     1860

gaauagauaa uuaugagaau cuaacaguac cguucgucgc agaugauuac uuagugcggc     1920

acgcauauaa aaacccuaau gaaauuuaua gcgaaauaag ugaaguugca aaauuaaaag     1980

acgcaaaaag ugaaguaaag aaaucacaau acuuuagcac auucacauua agaggaaguu     2040

auacuggagg agccuccaaa gguaaacuag aagaccaaaa agcuaugaac aaauuuauag     2100

augauagucu uaagaaacuu gacaccuauu cauggagugg auauaaaaca uuaacagcuu     2160

auuucacuaa cuauaaagua gauucaucaa aucgcguaac uuaugauguc guuuuccacg     2220

guuauuuacc caacgaagga gacaguaaaa acucacuacc auacgguaaa auaaauggca     2280

cuuacaaagg aacagaaaaa gagaaaauaa aauucaguuc ugaaggauca uucgacccag     2340

auggaaaaau agugagcuau gaaugggacu ucggagaugg uaauaaaagc aaugaagaaa     2400

auccagaaca caguuaugac aaaguaggua cauacacugu uaaauuaaaa gucacagacg     2460

auaaaggcga aaguucagua ucaacaacaa cagccgaaau aaaagaucua agcgaaaaca     2520

aacuacccgu cauauauaug cacguaccua aaaguggagc ccuuaaccaa aaagugguau     2580

ucuacggaaa aggaacauac gacccugacg gaagcauagc aggauaucaa ugggacuucg     2640

gugacgguuc ggacuucucu ucugaacaaa auccaagcca cguauacaca aagaaaggag     2700

aauacaccgu aacacuuaga guuauggaca gcucaggaca aaugucagag aaaacaauga     2760

aaaucaaaau uaccgacccu guauauccaa uaggaacuga aaaagaacca aauaacagua     2820

aagaaacagc uaguggaccg aucguuccag guauuccugu aaguggaaca aucgaaaaca     2880

caucagacca ggacuauuuu uauuucgaug uaauaacacc aggagaaguc aaaaucgaua     2940

uaaauaaacu aggauaugga ggggcuacau ggguaguaua cgaugaaaac aacaaugcag     3000

uauccuacgc gacagaugac ggacagaacc uuucaggaaa auucaaagcg gacaaaccag     3060

gcagguacua cauacaccua uacauguuca acggauccua uaugccuuau cgaauuaaua     3120

uagaaggauc cguaggccgu uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  7249
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt12)

<400>  7249
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguga cauucauauc ucuacuuuuc cuauucuccu      120

cagcauacuc aguacaaaac gaaucaaaaa gauacacagu gaguuacuua aaaacguuaa      180

acuacuauga ccuaguagac cuucuaguaa aaaccgaaau agaaaaucua ccagaccuau      240

uccaauacuc uucagaugcc aaagaauuuu auggaaauaa aaccagaaug aguuucauca      300

uggaugaaau cggaaggaga gcaccacaau acacggaaau agaucacaaa gguauaccca      360

cuuuaguaga agucguaaga gcaggauucu acuuaggauu ccauaacaaa gaacucaaug      420

aaauuaauaa aagaucuuuc aaagaaaggg uaauacccag cauacucgcc auacagaaaa      480

accccaacuu caaacuagga acagaaguac aagauaaaau aguaucagca acugguuuac      540

ucgcuggaaa ugaaaccgca ccaccagaag uaguaaacaa cuucaccccu auucuacaag      600

acugcauuaa aaauauagac agauacgccc uagacgacuu aaaaucgaag gcccucuuua      660

acguacuagc cgccccaaca uaugauauaa cagaauacuu aagagcaacc aaagaaaaac      720

cagaaaauac acccugguac ggaaaaauag acggauuuau aaaugaauua aagaaauuag      780

cguuauaugg gaaaauaaac gacaauaaua guuggauaau agacaacgga auauaccaca      840

uagcaccauu aggcaaacua cacuccaaua acaaaauagg gauagaaacc uuaacagaag      900

uaaugaaagu auauccauau cuaucaaugc aacauuugca aucagcagac caaauaaaac      960

gacauuauga uaguaaagac gcagaaggaa auaaaauacc acuagauaaa uucaagaaag     1020

aaggaaaaga aaaauauugu ccaaaaacau acacauucga ugacggaaaa guaauaauua     1080

aagccggugc ccggguagaa gaagaaaaag uaaaacgacu guauugggcu ucuaaagaag     1140

ucaauucaca auucuuuagg guauacggaa uugauaaacc ucuagaagaa gguaacccag     1200

acgacauccu aacaaugguc auauacaaua gcccggaaga auacaaauua aacucgguau     1260

uauacgggua ugacacaaau aacggcggca uguacauuga acccgaagga acguucuuca     1320

cauaugaaag agaagcacaa gaaucaacau acacacucga agaacuauuu agacacgaau     1380

auacacauua uuuacaaggg agauacgccg uacccggaca auggggucga accaaacuuu     1440

acgacaacga caggcuaaca ugguacgaag aagggggagc agaauuauuc gcaggaucaa     1500

caagaaccuc aggaauacua ccuagaaaaa guauaguauc aaauauacau aauacaacca     1560

ggaauaacag auauaaauua agugacacag uccauucaaa auauggagcc uccuuugagu     1620

ucuauaacua cgcauguaug uucauggauu acauguacaa caaagauaug ggaauccuaa     1680

acaaacuaaa cgaccuagcu aaaaauaacg auguugacgg auacgauaac uacauaagag     1740

accucagcuc aaacuaugca cuuaacgaca aauaucaaga ucauaugcaa gaaagaauag     1800

acaacuacga aaaucucaca guaccauucg uagcagacga uuauuuagua agacacgcau     1860

acaagaaccc uaacgaaauc uauuccgaaa uuagcgaagu agcgaaacuu aaagacgcaa     1920

aaagugaagu aaagaaaagu caauacuuca gcacauucac acuacgagga uccuacacag     1980

gcggcgcaag caaaggcaaa cuagaagauc aaaaagcaau gaacaaauuc auagacgauu     2040

cacucaagaa auuagauaca uauagcugga guggauacaa aacacuaacu gcauauuuca     2100

caaacuacaa aguugacagc ucaaauagag ucacauauga uguaguauuc cacggauauc     2160

uacccaauga aggugacagc aaaaacuccu uaccauacgg aaaaauuaac gggacauaca     2220

aaggaacaga aaaagagaaa auaaaauucu cauccgaagg uagcuuugac cccgauggaa     2280

aaauuguauc auaugaaugg gacuucggag acggaaauaa aucaaacgaa gaaaauccug     2340

aacacagcua ugauaaaguu ggcaccuaua ccgugaaacu aaaagugaca gaugacaaag     2400

gugaaucauc cguauccaca acgacagcag aaauuaaaga cuuaagcgaa aacaaacuac     2460

caguaauaua caugcaugua ccaaaauccg gcgcauuaaa ucaaaaaguc guauuuuaug     2520

gaaaagggac uuaugacccc gaugggucaa ucgcaggcua ucaaugggac uucggcgaug     2580

gcucagacuu cucaucagaa cagaacccau cucauguuua cacaaagaaa ggagaauaca     2640

caguaacauu acgagucaug gauucaucag gucaaauguc agagaaaaca augaaaauaa     2700

aaauaacaga uccgguuuac ccaauaggaa cagaaaaaga acccaacaau ucaaaagaaa     2760

cagcaagugg cccuauaguu ccagguauuc cuguaucagg uacaaucgaa aacacaucag     2820

accaggauua cuuuuacuuc gacgugauua cgccaggaga aguuaaaauc gauauuaaua     2880

aauuaggaua ugguggagcc acguggguag uauacgauga aaauaauaau gcaguaucau     2940

augccacaga ugacggacaa aaucuuucag ggaaauuuaa agcugauaaa ccaggaagau     3000

auuauauaca ccuuuacaug uucaacgguu cauacaugcc uuacagaaua aauauagaag     3060

gauccguagg uagauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  7250
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt12)

<400>  7250
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguga cauucaucuc acuauuauuu cuauucagua      120

gcgcauauuc uaugaaacga aaaugcuuau ccaaaagacu aaugcuagca auaacaaugg      180

caacaaucuu caccguaaau ucaacauuac caaucuacgc agccguagau aaaaacaaug      240

caacagcagc ucgaaggaga aggaaaaggg uacaaaacga aagcaaaaga uauaccguca      300

gcuaccuuaa aaccuuaaau uacuacgacu uaguagaucu cuuaguaaaa acagaaauag      360

aaaacuuacc cgauuuguuu caauauucau ccgacgcaaa agaguucuac ggaaauaaaa      420

caagaaugag cuucauaaug gacgaaauag gucggagagc uccccaauau accgaaauag      480

aucauaaagg aauaccaacc uuaguagaag uaguaagagc cggauuuuac cuuggcuucc      540

auaacaaaga acuaaacgaa auaaacaaac gauccuucaa agagcgcgua auaccaagua      600

uacuggccau ccagaaaaac ccaaacuuua aauuaggaac ggaaguucaa gacaaaauag      660

uaagugcaac agggcuccua gcaggaaacg aaacagcucc cccugaaguu guaaauaacu      720

ucacaccaau acuucaagac uguauuaaaa acauagacag auacgcauua gacgaccuua      780

aaagcaaagc guuauuuaac guacuagcug cacccacuua ugacauaacu gaauacuuaa      840

gagcaacaaa agaaaaacca gaaaacacac cuugguaugg caaaauagau ggauuuauaa      900

augaacuaaa gaaacuggca cuauauggca aaaucaacga uaauaacagu uggauaauag      960

acaacgguau auaucauaua gcaccacuag guaaauugca uucaaacaau aaaauuggua     1020

uagaaacguu aacagaggug augaaaguau acccauaccu aucuaugcaa cauuuacaau     1080

cagcggauca aauuaaaagg cacuaugauu caaaagaugc ggaagguaac aaaauaccac     1140

uagacaaauu caagaaagaa ggaaaagaaa aauauugucc caaaacauac acauuugaug     1200

augguaaagu aauaauaaaa gcaggggcuc gaguagaaga agaaaaaguu aaacgacuau     1260

acugggccuc aaaagaaguc aacucucaau uuuuccgcgu auacggaauc gauaaaccau     1320

uagaagaagg uaauccggau gauauauuaa ccauggugau cuacaacuca ccagaagaau     1380

acaaacuaaa uucaguccua uauggauacg acacuaauaa ugguggaaug uacauagaac     1440

cagaaggcac auucuucaca uacgaaagag aggcucaaga aucaacauac acacuagaag     1500

aauuauuccg acacgaauac acacauuacu uacaaggaag auacgcggua cccggacaau     1560

ggggaagaac aaaacuauac gauaaugauc gacuuacaug guaugaagaa ggaggagccg     1620

aacuauucgc aggauccacg cgcaccucag ggauucuucc aagaaaauca auaguaucaa     1680

auauacacaa uacaacacga aauaacagau auaaauuauc agacacagua cacuccaaau     1740

auggcgcaag uuucgaguuc uacaauuacg cauguauguu cauggauuac auguauaaca     1800

aagauauggg gaucuuaaac aaacuaaacg auuuagcgaa aaacaaugac guagacggcu     1860

augacaacua cauacgagac uuauccagca auuacgcacu uaacgauaaa uaccaagauc     1920

acaugcaaga aagaauagau aacuacgaaa aucuaacagu cccauuuguc gcagacgacu     1980

accuggugag acacgcuuac aaaaauccaa augaaauaua cucagaaaua agcgaaguag     2040

cuaaacucaa agacgccaaa agugaaguua agaaaaguca auacuuuuca acauucaccc     2100

uccggggauc auauaccggg ggagcaucua aaggaaaauu agaagaccaa aaagccauga     2160

auaaauuuau agaugacucc cuaaagaaac uggacacuua cuccuggagu ggguacaaaa     2220

cuuuaacagc uuauuucacc aacuauaaag uagacagcag caaucgaguc acauaugacg     2280

ucguguuuca ugguuacuua ccaaacgaag gagacagcaa aaacucacuu cccuauggua     2340

aaauaaacgg uacauacaaa ggaacagaaa aagagaaaau uaaauucucu ucugaaggau     2400

cauuugaucc agauggaaaa aucgugaguu augaauggga cuuuggagac ggaaacaaau     2460

cuaacgaaga aaacccagaa cacaguuaug auaaaguugg aaccuacaca guaaaacuaa     2520

aagugacuga cgauaaagga gaaucaucag ucaguacaac uacagccgaa auaaaagauc     2580

uaagcgaaaa uaaacucccc guaauauaua ugcacguccc aaaaucagga gccuuaaauc     2640

aaaaaguugu cuuuuacggu aaaggaacau acgaucccga uggaucaauc gcaggauauc     2700

aaugggacuu uggagauggu agcgauuucu ccagcgaaca aaaccccuca cacguauaua     2760

caaagaaagg agaguauaca guaacauuaa gagugaugga uagcucggga caaaugucag     2820

agaaaacaau gaaaauaaaa auuacggauc caguauaccc cauaggaaca gaaaaagaac     2880

caaacaauuc caaagaaacc gcuagugguc caaucguacc cggcauuccg gugagcggua     2940

cuauagagaa cacaucagac caagauuacu uuuacuucga cgucauuaca ccaggcgaag     3000

uaaaaauaga uauaaauaaa uuagguuacg gaggugcaac uuggguagua uaugacgaga     3060

acaacaacgc cgucucauac gcaaccgacg acggucaaaa ucuaucagga aaauucaaag     3120

cagacaaacc agguagauac uacauucacc uauacauguu caauggaagu uacaugccau     3180

acagaauaaa cauagaagga uccguuggaa gauaaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  7251
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt12)

<400>  7251
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuuuucgc augccuacuc ggagcagcau      120

ucgcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaucaa uaagaccacc auacccauca uacggauacg      240

aaccaauggg aggaugguua caccaccaaa uaauaccagu acuaucacaa caacacccac      300

ccacacacac auuacaacca caccaccaca uaccaguagu accagcacaa caaccaguaa      360

uaccacaaca accaaugaug ccaguaccag gacaacacuc caugacacca auacaacacc      420

accaaccaaa ccuaccacca ccagcacaac aaccauacca accccaacca guacaaccac      480

aaccacacca accaaugcaa ccacaaccac caguacaccc aaugcaacca cuaccaccac      540

aaccaccacu accaccaaug uucccaaugc aaccacuacc accaaugcuc ccagaccuaa      600

cacuagaagc cuggccauca acagacaaaa caaaaagaga agaaguagac uaaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  7252
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt12)

<400>  7252
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccucuaccuc cacauccagg ucacccugga uauauaaauu      120

ucucuuacga aguacuuaca ccucuaaaau gguaucaauc uauacgucca ccuuacccuu      180

cauauggaua ugaaccuaug gguggauggu aaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  7253
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt12)

<400>  7253
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca ccaccaaugc      180

uaccagaccu aacacuagaa gcauggccau caacagacaa aacaaaaaga gaagaaguag      240

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  7254
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt12)

<400>  7254
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa ucaauaagac      240

caccauaccc aucauacgga uacgaaccaa ugggaggaug guaaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  7255
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt12)

<400>  7255
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa ucaauaagac      240

caccaccaau gcuaccagac cuaacacuag aagcauggcc aucaacagac aaaacaaaaa      300

gagaagaagu agacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  7256
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt12)

<400>  7256
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uccuauucgc uugccuagua ggagcagcau      120

ucgccaugcc auuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acucaaaugg uaccaaucaa ugauaagacc accauacuca ucauacggau      240

acgaaccaau gggaggaugg cuacaccacc aaauaauacc aguaguauca caacaacacc      300

cauuaacaca cacacuacaa ucacaccacc acauaccagu aguaccagca caacaaccaa      360

gaguaagaca acaagcacuc augccaguac ccggacaaca aucaaugaca ccaacacaac      420

accaccaacc caaccuacca cuaccagcac aacaaccauu ccaaccacaa ccaguccaac      480

cacaaccaca ccaaccaaug caaccacaac caccuguaca accaaugcaa ccacuauuac      540

cacaaccacc acucccaccc auguucccac uaagaccacu accaccaaua cuaccagacc      600

uacaccuaga agcauggcca gcaacagaca aaacaaaaca agaagaaguc gacuaaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  7257
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt12)

<400>  7257
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aaugauaaga ccaccauacu      180

caucauacgg auacgaacca augggaggau gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  7258
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt12)

<400>  7258
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aaugauaaga ccaccaccaa      180

uacuaccaga ccuacaccua gaagcauggc cagcaacaga caaaacaaaa caagaagaag      240

uagacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  7259
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt12)

<400>  7259
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaucca ggacacccag      180

gauauauaaa uuucucauac gaaguauuaa caccacuaaa augguaucaa ucaaugauaa      240

gaccaccaua cagcucauac ggauacgaac caaugggagg augguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  7260
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt12)

<400>  7260
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaucaa ucaaugauaa      240

gaccaccacc aauacuacca gaccuacacc uagaagcaug gccagcaaca gacaaaacaa      300

aacaagaaga aguagacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  7261
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt12)

<400>  7261
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaccugga uauuauucgc augccuacua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc uccuacgaag      180

uauuaacacc acuaaaaugg uaccaaaaca ugauaagaca ccccuacaca ucauacggau      240

acgaaccaau gggaggaugg cuacaccacc aaauaauacc cguaguauca caacaaacac      300

cacaaucaca cgcacuacaa ccccaccacc acauaccaau gguaccagca caacaaccag      360

gaauaccaca acaaccaaug augccacuac caggacaaca cucaaugaca ccaacacaac      420

accaucaacc aaaccuacca cuaccagcac aacaaccauu ccaaccacaa ccaguacaac      480

cacaaccaca ccaaccacua caaccccaau caccaaugca ccccauacaa ccacuacuac      540

cacaaccacc acuaccacca auguucucaa ugcaaucacu acuacccgac cuaccacuag      600

aagcauggcc agcaacagac aaaacaaaac gcgaagaagu agacuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  7262
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt12)

<400>  7262
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa uaugauaaga cacccauaca      180

caucauacgg auacgaacca augggaggau gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  7263
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt12)

<400>  7263
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa caugauaaga cacccaucac      180

uacuaccaga ccuaccacua gaagcauggc cagcaacaga caaaacaaaa agagaagaag      240

uagacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  7264
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt12)

<400>  7264
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaucca ggacacccag      180

gauauauaaa uuucucauac gaaguauuaa caccacuaaa augguaucaa aauaugauaa      240

gacauccaua uacaucauac ggauacgaac caaugggagg augguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  7265
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt12)

<400>  7265
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa aacaugauaa      240

gacacccauc acuacuacca gaccuaccac uagaagcaug gccagcaaca gacaaaacaa      300

aaagagaaga aguagacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  7266
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt12)

<400>  7266
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uauuauucgc augccuacua ggagcagccu      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacauaa      180

gacauccaua cacaucauac ggauaugaac caaugggagg auggcuacac caccaaauaa      240

uaccaguagu aucacaacaa accccacaau cacacgcacu acaaccacac caccacauac      300

caaugguacc agcacaacaa ccaggaauac cacaacaacc aaugaugcca uuaccaggac      360

aacacuccau gacaccaaca caacaccacc aaccaaaccu accacuacca gcacaacaac      420

cauuccaacc acaaccagua caaccacaac cacaccaacc acuacaacca caaucaccaa      480

ugcacccaau acaaccacua cuaccccaac caccacuacc accaauguuc ucaaugcaau      540

cacuacuacc agaccuacca cuagaagcau ggccagccac agacaaaaca aaacgagaag      600

aaguagacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  7267
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt12)

<400>  7267
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uauucuucgc augcuuacua ggagcauccu      120

uagcaaugcc acuaccacca cacccaggcc acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaaaca ugauaagaca cccauacaca ucauacggcu      240

acgaaccaau gggcggcugg cuacaccacc aaauuauacc aguaguauca caacaaacac      300

cacaaucaca cgcacuacaa ccccaccacc acauaccaau gguaccagca caacaacccg      360

gaauaccaca acaaccaaug augccacucc caggacaaca cucaaugaca ccaacacaac      420

accaccaacc aaaccuccca cuaccagcac aacaaccauu ccaaccccaa ccaguacaac      480

cacaaccaca ccaaccacua caaccacaau caccuaugca cccaauacaa ccauuacuac      540

cccaaccacc acuaccacca auguucucaa ugcaaucacu acuaccagac cuaccacuag      600

aagcauggcc agcaacagac aaaacaaaaa gagaagaagu cgacuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  7268
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt12)

<400>  7268
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaucaaaaca ugauaagaca cccaucacua uuaccagacc      240

uaccacuaga agcauggcca gcaacagaca aaacaaaaag agaagaagua gauuaaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  7269
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt12)

<400>  7269
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggcgcagcau      120

ucucaaugcc acuaccacca caccccggac acccaggcua cauaaacuuc ucauacgaag      180

auuuauacuu agaagcaaua agaauagaca gaacagcauu uguauuaaca ccacuaaaau      240

gguaccaaaa caugauaaga cacccauaca caucauaugg auacgaaccc augggaggau      300

ggcuacacca ccaaauaauc ccaguaguau cacaacaaac accacaauca cacgcccuac      360

aaccacacca ccacauacca augguaccag cacaacaacc aggaauacca caacaaccca      420

ugaugccacu accaggacaa cacucaauga caccaacaca acaccaccaa cccaaccuac      480

cacuaccagc acaacaacca uuccaaccac aaccaguaca accacaacca caccaaccau      540

uacaaccaca aucaccaaug cacccaauac aaccccuacu accacaacca ccacuaccac      600

caauguucuc aaugcaauca cuacuaccag accuaccacu agaagccugg ccagcaacag      660

acaaaacaaa aagagaagaa guagacuaag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  7270
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt12)

<400>  7270
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggagcagcau      120

ucucaaugcc acucccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaaaca ugauaagaca cccaacacca caaucacacg      240

cacuccaacc acaccaccac auaccaaugg uaccagcaca acaacccgga auaccacaac      300

aaccaaugau gccacuacca ggacaacacu ccaugacacc aacacaacac caccaaccaa      360

accucccacu accagcacaa caaccauucc aaccacaacc aguacaacca caaccacacc      420

aaccacuaca accacaauca cccaugcacc caauacaacc acuacuccca caaccaccac      480

uaccaccaau guucucaaug caaucacuac uaccagaccu cccacucgaa gcauggccag      540

caacagacaa aacaaaaaga gaagaaguag acuaaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  7271
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt12)

<400>  7271
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacucccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacucaca ccccuaaaau gguaccaaaa caugauaaga caccccuaca      180

caucauacgg auacgaaccc augggaggau ggcuacacca ccaaauaaua ccaguagucu      240

cacaacaaac accacaauca cacgcacucc aaccacacca ccacauccca augguaccag      300

cacaacaacc aggaauacca caacaaccaa ugaugccacu accaggacaa cacucaauga      360

caccaacaca acaccaccaa ccaaaccuac cacuacccgc ccaacaacca uuccaacccc      420

aaccaguaca accacaacca caccaaccac uccaaccaca aucaccaaug cacccaauac      480

aaccacuacu accacaacca ccacucccac caauguucuc aaugcaauca cuacucccag      540

accuaccacu agaagcaugg ccagcaacag acaaaacaaa aagagaagaa guagacuaag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  7272
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt12)

<400>  7272
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccugggguug caagacuacc guuacuauug ggauuacuac      120

uauuaccaag gccaggaaga ccauuagauu uagcagauua uacguaugau uuagcagaag      180

aagacgauag ugaaccauua aauuauaaag auccauguaa agcagccgcg uuuuuagggg      240

acauagcacu agaugaagaa gaucuaagag cauuucaagu acaacaagca guugaccuaa      300

gaagacacac agcuagaaaa ucaucaauua aagccgcugu cccgggaaau acgaguacac      360

cgaguuguca aucuacuaac ggacagccac aacguggugc augcggaaga uggagaggac      420

gcucaaggag ucggagagcg gcaacaagca gaccagaaag ggucuggcca gauggaguaa      480

uaccuuucgu aauaggagga aauuuuacag gaagucaaag agcaguauuc cgucaagcua      540

ugagacauug ggaaaaacau accuguguaa cguuuuuaga aagaacagau gaagauaguu      600

acauaguguu uacguaucga ccaugcggau guuguucuua cguaggaaga cgagggggug      660

guccccaagc aauaucaaua gguaaaaacu gcgauaaauu cgggauagua guacaugaac      720

uagggcaugu aguuggauuu uggcaugaac acacacgacc cgauagagau agacaugucu      780

caauaguaag ggaaaacaua caacccggac aagaauauaa uuucuuaaaa auggaaccac      840

aagaaguuga aaguuuaggu gaaacguaug acuucgauag uauuaugcau uaugcacgaa      900

auaccuuuag uagaggaauu uuucuugaca cuauaguacc gaaauaugaa guaaauggug      960

uaaaaccacc aauaggucaa agaacaagau uaucaaaagg agauauagca caagcucgaa     1020

aacuguacaa augcccagcu uguggugaaa cauugcaaga uucaacagga aauuucagua     1080

gcccagaaua cccaaacgga uauagugcgc auaugcauug cgucuggagg auuaguguaa     1140

caccagguga gaaaauaaua cuaaauuuua cgaguuuaga cuuauaucga agcagauuau     1200

guugguauga cuauguugaa guuagagaug gauuuuggag aaaagcacca uuaagaggaa     1260

gauuuugugg aucaaaacua ccagaaccaa uaguaaguac agauaguagg cuuuggguag     1320

aguucagaag cucgaguaau uggguaggca aaggauucuu ugcagucuau gaagccauau     1380

guggagggga uguuaagaaa gacuauggac acauacaauc accuaauuau ccggacgauu     1440

accgaccaag caaaguuugu auuuggcgga uucaaguaag cgaagguuuc cacguaggac     1500

uuacauucca aucuuuugaa auugaacgcc augauaguug cgcauacgac uaucuagaag     1560

uaagagaugg ucauagcgaa aguucaacac uaauuggaag auacugcgga uaugaaaaac     1620

cugacgauau aaaaucaaca agcagucgau uauggcuaaa auuugugagu gacggaagca     1680

uaaauaaagc uggcuucgcu guaaacuuuu ucaaagaagu agaugaaugu aguagaccaa     1740

auaggggcgg augugaacaa cguuguuuaa auacuuuagg cucguauaaa ugcagcugug     1800

aucccggaua ugaacucgca ccagauaaaa gaagauguga agcagcaugu ggaggauuuu     1860

ugacaaaacu uaaugguucc auaaccaguc caggguggcc aaaagaauau ccgccaaaua     1920

aaaauugcau uuggcagcua guagcuccaa cucaauaccg uaucaguuua caauucgacu     1980

ucuuugaaac agaaggcaau gacguaugca aauacgauuu uguagaaguu agaucugggc     2040

uaaccgcuga caguaaauua cauggaaaau uuuguggcuc agaaaaacca gaaguaauca     2100

caucacaaua caauaacaug agagucgagu uuaaaagcga uaacacaguu aguaagaaag     2160

guuuuaaagc ccauuucuuu agugauaaag augaaugcuc aaaagauaau ggaggguguc     2220

aacaagauug cguaaauaca uuuggaagcu acgaaugcca auguagaucc ggauuuguac     2280

uccaugauaa uaaacacgau uguaaagaag caggauguga ccacaaagua accucuacau     2340

cggggacuau cacgagucca aacuggccag auaaauaccc uucaaagaaa gaaugcacuu     2400

gggcgaucag uucuacucca ggacauaggg uuaaauuaac auuuauggaa auggacauag     2460

aaucacaacc ugaaugugcu uaugaccauu uagaaguuuu ugauggaaga gaugcuaaag     2520

cgccuguuuu aggucgguuu ugcggaagua aaaagccuga accugucuua gccacuggcu     2580

caaggauguu uuuaagguuu uauucagaca acucagucca aagaaaagga uuucaagcaa     2640

gucaugcgac agaaugcgga ggccaaguac gagcagaugu aaaaacaaaa gaucuuuauu     2700

cucaugcaca auuuggugau aauaauuauc cuggaggagu ugauugugag uggguaauag     2760

uagcagaaga agguuaugga guugaauuag uauuucaaac guuugaagua gaagaagaaa     2820

ccgauugcgg uuaugacuac auggaacuau ucgaugguua ugauucaaca gcuccuagau     2880

uaggaagaua uuguggguca ggcccgccag aggaaguaua uagugcagga gauagcguuc     2940

uaguaaaauu ucacagcgac gacacaauaa ccaagaaagg auuccaucua cgcuauacau     3000

caacuaaauu ccaagauaca cuacauagca gaaaauaagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  7273
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt12)

<400>  7273
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgcaggaa caagaugucu acuagcacua uuacuuccac      120

aaguucuacu aggaggagca gcuggauuag uaccagaauu aggaagaaga aaauuugcgg      180

cagcaucauc uggaagaccc aguucacaac caucagacga aguauuauca gaauuugaac      240

uuagacuacu uagcauguuc ggauuaaaac aacgucccac accaucuaga gaugcaguag      300

uaccacccua uaugcuugac cuauacagac gucacagcgg ccaaccagga ucaccagcac      360

cagaccauag acuagaaaga gccgcaucaa gagcaaacac aguaagauca uuccaccaug      420

aagaaagcuu agaagaauua ccagaaacau cagguaaaac uacaagaagg uuuuucuuua      480

acuuaagcuc uauaccaaca gaagaauuua uaacaucagc agaauuacaa guauucagag      540

aacaaaugca agacgcacua ggcaauaaua gcagcuuuca ccacagaaua aauauauaug      600

aaauuauaaa accagcaaca gcaaacucaa aauuuccagu aacaagacua uuagacacac      660

gacuaguaaa ucaaaaugca ucaagauggg aauccuucga cguaacacca gcaguaauga      720

gauggacagc acaaggacac gcaaaccaug gauuuguagu agaaguagcu cacuuagaag      780

aaaaacaagg aguaaguaaa cgucauguaa gaauuagcag aaguuuacau caagacgaac      840

auuccugguc ucaaauuaga ccacuacuag uaacauucgg acaugacgga aaaggacacc      900

cacuacacaa aagagaaaaa cgacaagcaa aacauaaaca acguaaaaga uuaaaauccu      960

cauguaaaag acauccauua uacguagauu ucucagacgu aggauggaac gacuggauag     1020

uagcaccacc cggauaccac gcuuucuauu gccauggaga augcccauuc ccacuugcag     1080

accaucuaaa cagcacaaau cacgccauug uacaaacauu aguaaacagc guaaacucca     1140

aaauaccaaa agcaugcugc guuccaacag aauuaagcgc aauaucaaug uuauacuuag     1200

acgaaaauga aaaaguagua cuaaaaaauu accaagacau gguaguagaa ggcuguggau     1260

gccgcuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  7274
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt12)

<400>  7274
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaccaggaa auagaaugcu uaugguagua uuacuaugcc      120

aaguauuacu aggaggugca ucccaugccu cauuaauacc agaaaccggc aaaaaaaaag      180

uagcugaaau acaaggacau gcaggaggaa gaagauccgg acaaucacac gagcuacuaa      240

gagacuuuga agcuacauua uuacaaaugu uuggauuacg aagaagacca caaccuucaa      300

aaucagcugu cauuccagau uauaugagag acuuauauag auuacaaucu ggugaagaag      360

aagaagaaca aauccacuca acuggacugg aauauccaga aagaccagcu ucaagagcua      420

auacuguucg uucauuucau cacgaagaac auuuagaaaa cauaccagga acaagcgaaa      480

auagugcauu uagauucuua uucaaccuau ccagcauucc agaaaacgaa guaauaucaa      540

gugcagaauu aagauuauuu cgugaacaag uagaucaagg accagacugg gaaagaggau      600

uucacagaau uaacauauau gaaguuauga aaccaccugc agaagucgua ccaggucacc      660

uaauaacaag auuauuagau acaagacuag uacaucauaa cgucacaaga ugggaaacuu      720

uugacguauc accagcagua uuacgaugga cacgagaaaa acaaccaaau uacggucuag      780

caauagaagu aacacaccua caucaaacaa gaacccacca aggacaacau guacgaauau      840

caagaucauu accacaagga agcggaaacu gggcacaauu aagaccacua cuaguuacuu      900

uuggacacga uggaagagga cacgcacuaa cacggagaag aagagcaaaa cguucaccaa      960

aacaccauuc ucaaagagca agaaaaaaaa auaaaaacug cagacgacau agcuuauaug     1020

uagauuucuc agauguaggg uggaaugacu ggauaguagc accuccagga uaccaagcau     1080

uuuacuguca cggugacugu ccauuucccu uagccgauca cuuaaacuca acaaaucaug     1140

caauaguaca aacacuagua aacaguguaa acucaaguau accuaaagca ugcugcguac     1200

caacagaacu aucagcaauu ucaauguuau accuagacga auaugacaaa guuguauuaa     1260

aaaauuauca agaaaugguu guagaaggau guggauguag auaaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  7275
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt12)

<400>  7275
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaggacuag guagaagggc ccaauggcua uguugguggu      120

ggggucuauu auguucaugu uguggacccc cuccucuaag accaccauua ccagcugcug      180

cagcagcagc agccggcggg caauuacuag gagauggagg cucgccagga agaacagaac      240

aaccaccacc aucaccacaa ucaucaucag guuuccuaua cagacgacuu aaaacacaag      300

aaaaacgaga aaugcaaaaa gaaauauuau cuguuuuagg ucuaccacau agaccuagac      360

cacuacaugg ccuacaacaa ccucaaccuc cagcccuucg ccaacaagaa gaacaacaac      420

aacaacaaca auuaccaaga ggugagccac cacccgguag auuaaaauca gcuccuuuau      480

ucauguuaga uuuauacaac gcccuauccg ccgauaauga ugaagaugga gcaucagaag      540

gcgagaggca acaaucaugg ccgcaugaag cagcuucauc aucacaacgc cgacaaccac      600

cuccuggugc ugcacaucca uuaaaucgua aaagccuacu ugcaccagga ucaggaucug      660

gaggagccuc accacuaaca agcgcacaag auucagcauu ucuaaaugac gcugauaugg      720

ucaugaguuu uguaaaucua guagaauacg auaaagaguu cucuccaaga caaagacauc      780

auaaagaauu uaaauuuaau cuaucucaaa ucccagaagg agaaguagua acagcggcag      840

aauuuagaau auauaaagau uguguaaugg gaucauucaa aaaucaaacu uuucuaauuu      900

caauauacca aguauuacaa gaacaucaac aucgcgacuc agaccucuuu uuacucgaca      960

cccgaguugu uugggcaucc gaagaaggcu ggcuagaauu ugauauuaca gcaacaucaa     1020

auuuaugggu aguaaccccu caacauaaca uggguuuaca auuaagugua guaacaagag     1080

acggaguuca cguccaccca agagcugcag gauuaguagg aagagaugga ccauaugaca     1140

aacaaccauu caugguugca uucuuuaaag uuagugaagu ucauguacga acaacaagau     1200

cagcaaguuc aagaagaaga caacaaucua gaaaccgaag uacacaauca caagauguug     1260

cacgaguauc aucugccagu gacuauaauu caucagaauu aaaaacagca uguagaaaac     1320

acgaauuaua cguaucauuu caagauuuag guuggcaaga cuggauaaua gcaccaaaag     1380

gauacgcagc aaauuauugu gacggcgaau guucauuucc uuuaaaugca cauaugaaug     1440

caacaaacca ugcaauaguc caaacauuag uccacuuaau gaauccagaa uacguaccaa     1500

aaccuuguug ugccccaaca aaauuaaaug caaucucagu acuauacuuc gaugauaauu     1560

caaauguaau auuaaagaaa uaccgaaaua ugguaguaag agcuugcggc ugucacuaag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  7276
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt12)

<400>  7276
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caugucagau cacuuagagc agcagcccca cauucuuucg      120

uagcauuaug ggcaccauua uucuuauuaa gaagcgcacu agcagacuuu ucauuagaca      180

augaaguaca uaguagcuuu auacauagac gccuaagauc acaagaaaga cgagaaaugc      240

aaagagaaau ccuaucaaua uuaggauuac cacauagacc aagaccucau cuacaaggaa      300

aacacaacuc cgcuccaaug uucauguuag accuauauaa cgcaauggcu gucgaagaag      360

gaggaggucc aggaggacaa gguuuuaguu aucccuacaa agcaguauuu agcacacaag      420

gcccaccacu cgcaagcuua caagauuccc auuuccuaac agaugccgau augguuauga      480

guuucguuaa ucuuguagaa cacgauaaag aauucuucca cccuagauau caccaucgag      540

aguucagauu cgaucuuuca aaaauaccag aaggagaagc cguuaccgca gcagaauuua      600

gaauauauaa agauuacauc cgcgaacgau uugacaauga aacauucaga auaucaguau      660

aucaaguacu acaagaacau cuagggagag aaucagaucu auuuuuauua gacucuagaa      720

cacuaugggc aucagaagaa ggaugguuag uuuucgauau aacagccaca agcaaucacu      780

ggguaguaaa cccuagacac aacuuaggau uacaauuaag cguagaaaca cucgacggcc      840

aaaguauaaa ccccaaacua gcaggacuaa uaggacgaca cggcccacaa aacaaacaac      900

cauuuauggu cgccuuuuuc aaagcuacag aaguacauuu ccgaucaaua cgaucuacag      960

gauccaaaca aagaucacaa aacagaucua aaacaccaaa aaaucaagaa gcauuaagaa     1020

uggccaaugu agcagaaaau agcucaucag aucaacgaca agcaugcaaa aaacaugaac     1080

uauacgugag uuucagagau cucggauggc aagauuggau aauagcacca gaaggauaug     1140

cagccuauua uugugaaggu gaaugugcau uuccacuaaa uucuuacaug aaugcaacca     1200

aucacgcaau aguucaaaca cuaguacacu uuauaaaccc agaaacagua ccaaaaccuu     1260

guugcgcacc aacacaauua aacgcaaucu caguauuaua cuucgaugau aguucuaacg     1320

uaauauuaaa aaaauacaga aacaugguag ucagagcaug cgguugucac uaaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  7277
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt12)

<400>  7277
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagcaucag cagcacuacu augccuacua cuaacagcag      120

cagcauucuc accacaagga cuagcacaac caguaggaau aaacacauca acaacaugcu      180

gcuacagauu cauaaacaaa aaaauaccaa aacaaagacu agaaucauac agaagaacaa      240

caucaucaca cugcccaaga gaagcaguaa uauucaaaac aaaacuagac aaagaaauau      300

gcgcagaccc aacacaaaaa uggguacaag acuucaugaa acaccuagac aaaaaaacac      360

aaacaccaaa acuauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  7278
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt12)

<400>  7278
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuacucacgu ugauaauauu auuaccagua guaucaaaau      120

ucucuuuugu uagccuaagu gccccacaac auuggucuug uccagaaggg acguuagccg      180

ggaauggaaa caguacaugu gugggaccug ccccauuuuu aauauuuuca cacggaaauu      240

ccaucuuuag aaucgauacu gaagggacaa auuaugaaca auuaguugua gaugccggug      300

uaucaguaau cauggacuuc cauuauaaug aaaaacggau uuacuggguu gaucucgaaa      360

gacaacuacu ucaaagagug uuuuuaaaug ggaguaggca agaaagaguc uguaauauug      420

agaaaaaugu aucaggaaug gcuauaaauu ggauaaacga agagguaaua uggucuaauc      480

aacaagaagg uauuauaacu gugacugaua ugaaaggaaa uaacucacau auccuccuau      540

cugcucuaaa auauccugcu aacguggcag uugauccagu cgaacgauuu aucuuuuggu      600

caucagaggu cgcaggaucg cuauauagag cagacuuaga ugguguagga guaaaagcau      660

uacuagaaac cagcgagaaa auaacugcag uaaguuuaga uguacucgac aaaagauuau      720

ucuggauaca auacaauaga gaaggaucaa auucacuaau auguucuugu gacuaugaug      780

gcggaagcgu ccacauaucu aaacacccca cacaacauaa uuuauuugcg augaguuuau      840

uuggugauag aauauuuuau aguacgugga aaaugaaaac cauauggaua gcuaauaaac      900

auacaggaaa agacaugguc cgaauaaacc uacacucauc cuuuguaccu cuaggggaau      960

ugaaaguagu acauccacua gcacaaccaa aagcggaaga cgacacaugg gaaccggaac     1020

aaaaacucug uaaacucaga aaggguaauu guucgaguac uguaugugga caagaucuac     1080

aaagccauuu auguaugugc gcagaaggau augcuuuauc aagagaucga aaauauugcg     1140

aagaugucaa ugagugugca uuuuggaauc auggauguac ccuuggcugc aaaaauaccc     1200

caggcucaua uuauugcacu uguccaguag gauuuguauu guuaccugau ggaaagcgau     1260

gucaucaacu uguaaguugu ccacgaaaug uuagugaaug uucacaugau ugcguguuaa     1320

caucagaagg cccauuaugc uucugcccag aaggaucagu guuagaaaga gauggcaaaa     1380

cuugcagugg augcaguagc ccagacaaug guggauguag ucaauuaugu guuccguuau     1440

ccccaguguc gugggaaugu gacuguuuuc caggauauga uuuacagcua gacgaaaaau     1500

cuugcgcagc aagcggucca caacccuuuu uacuauuugc aaauucccaa gacauucguc     1560

acaugcauuu ugaugguacu gauuauggua cauuauuauc acaacaaaug gguaugguau     1620

augcauuaga ccaugauccu gucgaaaaca aaauauauuu cgcucauaca gccuuaaagu     1680

ggaucgaacg cgcuaacaug gauggaaguc aaagagaaag gcucauugaa gaaggagucg     1740

auguacccga aggcuuagca guagacugga uaggccgccg auuuuauugg acagauagag     1800

guaaaagucu uauaggacgu ucagacuuaa auggaaaaag aaguaaaauu auaacaaaag     1860

aaaacauauc acaaccuagg ggaauagcag uacauccaau ggcaaaacgc cucuuuugga     1920

cagauacagg cauaaauccu agaauugaaa guucuagcuu acagggacua ggccggcuag     1980

uaauugccuc aucagaccua auauggccaa gugggauaac cauagauuuu cucacggaca     2040

aauuguauug gugcgaugca aaacagucag uaauagaaau ggcuaaucuc gaugguucaa     2100

agagaaggag auuaacacag aacgauguug gucacccauu cgcaguagca guauucgagg     2160

auuacgucug guuuucggau ugggcaaugc caaguguaau gagaguaaac aaaagaacag     2220

guaaagauag aguacgauua caaggaucca uguuaaagcc cuccucauua guagucguuc     2280

auccauuggc uaaaccagga gccgacccau gcuuauacca aaaugguggu ugugaacaca     2340

uuuguaagaa aagauuagga acagccuggu guucaugcag agaaggcuuc augaaagcau     2400

cagauggaaa aacaugccua gcauuagaug gacaccaacu acuagcagga ggagaaguug     2460

accucaaaaa ccaaguaacg cccuuagaua uauuaaguaa aacucgaguu agugaggaca     2520

acauaacaga aagucaacac auguuagugg cugaaauaau gguaagugau caagacgauu     2580

gugcaccagu aggauguuca auguaugcac gcuguaucuc agaaggcgaa gaugcaacuu     2640

gccaaugccu aaaaggcuuc gcgggcgaug gaaaacuaug uucagacaua gaugaaugug     2700

aaaugggugu uccuguaugu cccccagcgu ccucaaaaug cauaaauacc gaaggcggcu     2760

auguaugucg uuguucagaa ggguaccaag gugauggaau ccauuguuua gauauagacg     2820

aaugucaauu aggcgaacau aguuguggug agaacgcuuc uugcaccaac acagaaggag     2880

guuacacaug uaugugcgca gggaggcuaa gugagccagg auuaauuugu ccagauagua     2940

caccaccucc ccaccuaaga gaggaugauc aucauuacuc aguaagaaau ucagauagug     3000

aauguccauu aucucacgau gguuacugcc uacaugacgg uguaugcaug uauauagaag     3060

ccuuagauaa auaugcuugu aacuguguag ucggcuacau aggagaaagg ugucaauaua     3120

gggaccuaaa auggugggaa uuacgacaug cuggccaugg gcaacaacaa aaaguaauag     3180

uuguagcagu cugugucgua guucuaguaa ugcuccucuu acuaucccua uggggugcuc     3240

auuauuaccg aacgcaaaaa cuucugagua aaaauccuaa aaauccauac gaagaaucau     3300

caagagaugu acgaucaagg agaccagccg auacagaaga ugggaugucg ucuugcccac     3360

agccaugguu cguuguaaua aaagaacacc aagauuugaa aaacggaggu caaccugucg     3420

caggagagga uggacaagcu gcagauggua guaugcaacc cacaaguugg agacaagaac     3480

cccaauuaug cggaauggga acggaacaag ggugcuggau uccaguaucg agcgacaaag     3540

ggucuugccc ccaaguaaug gaaagaucgu uccauaugcc cucauacgga acgcaaacuu     3600

uagaaggagg aguagagaaa ccacauuccu uacuaagcgc aaauccauua uggcaacaac     3660

gagcuuuaga uccaccacau caaauggaau ugacacaaua aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  7279
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt12)

<400>  7279
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagcaggaa gaagaaugga aaugcuaugu gcaggaagag      120

uaccagcacu auuacuaugu cuaggauucc aucuauuaca agcaguauua aguacaacag      180

uaauaccaag cuguauacca ggagaaagcu cagacaauug cacagcauua guacaaacag      240

aagacaaucc aagaguagca caaguaagca uaacaaaaug cucaagugau augaauggau      300

auugcuuaca cggacaaugu auauaucuag uagacaugag ccaaaacuau ugcagaugcg      360

aaguaggaua cacgggagua agaugugaac acuucuuucu aacaguacau caaccacuau      420

caaaagaaua cguagcauua acaguaauau uaauaauacu auuucuaaua acaguaguag      480

gaagcacaua cuauuucugu agaugguaca gaaacagaaa aucaaaagaa ccaaaaaaag      540

aauaugaaag aguaacauca ggagauccag aacuaccaca aguauaagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  7280
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt12)

<400>  7280
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagaaggag aaauaacaac auucacagca cuaacagaaa      120

aauucaaccu accaccagga aacuacaaaa aaccaaaacu acuauacugc ucaaacggag      180

gacacuucuu aagaauacua ccagacggaa ccguagacgg aacaagagac agaucagacc      240

aacacauaca acuacaauua ucagcagaau caguaggaga aguauacaua aaauccacag      300

aaacaggaca auacuuagca auggacacag acggacuacu auacggauca caaacaccaa      360

acgaagaaug ccuauuccua gaaagacuag aagaaaacca cuacaacaca uacauaucaa      420

aaaaacacgc agaaaaaaac ugguucguag gacuaaaaaa aaacggauca ugcaaaagag      480

gaccaagaac acacuacgga caaaaagcaa uacuauuccu accccuacca guauccucag      540

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  7281
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt12)

<400>  7281
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaggggugg gaggaggaga cguagaagac guaacaccaa      120

gaccaggagg augucaaaua aguggaagag gagcaagagg uuguaaugga auaccaggag      180

cggcagcaug ggaagcagca uuaccgagaa gaagaccgag aagacaccca aguguaaauc      240

cuagaucaag agcagcugga agcccaagaa cacgaggaag aagaacagaa gaaaggccua      300

guggaaguag auuaggggac agaggaagag gaagagcauu gccaggagga agacuaggcg      360

gaagaggaag aggaagagca ccagaaagag uaggagguag aggaagagga agaggaacag      420

cagcaccaag agcagcacca gcagcaaggg gaaguagacc aggaccagcg ggaacaaugg      480

cagcaggaag uauaacaaca cuuccagcau ugccagaaga uggaggaagu ggcgcauuuc      540

cgccaggaca uuuuaaagau ccaaagagau uauacuguaa aaauggaggu uuuuuuuuaa      600

gaauacaucc agauggaaga guagauggag uaagagaaaa aagugaucca cauauaaaau      660

uacaauuaca agcagaagaa agaggaguag uaaguauaaa aggaguaugu gcaaacagau      720

auuuagcaau gaaagaagau ggaagauuac uagcaaguaa auguguaaca gaugaauguu      780

uuuucuuuga aagauuagaa aguaauaauu auaauacgua ccgaaguaga aaauauacaa      840

guugguaugu agcguuaaaa agaacaggac aauauaaauu aggaagcaaa acaggaccgg      900

gacaaaaagc aauauuauuu uuaccuauga gugcgaaaag uuaaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  7282
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt12)

<400>  7282
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uacuaacaug gauacuacca acacuacuau      120

acagaagcug cuuccacaua auaugcuuag uaggaacaau aagccuagca uguaacgaua      180

ugacaccaga acaaauggca acaaauguaa acugcagcuc acccgaaaga cacacaagau      240

cauacgacua cauggaaggc ggagacauaa gaguaagaag acuauucugc agaacacaau      300

gguacuuacg aauagacaaa agaggaaaag uaaaaggaac acaagaaaug aaaaacaacu      360

acaacauaau ggaaauaaga acaguagcag uaggaauagu agcaauaaaa ggaguagaau      420

cagaauucua ccuagcaaug aacaaagaag gaaaacuaua cgcaaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa uuaauacuag aaaaccacua uaacacauac gcaagcgcaa      540

aauggacaca caacggagga gaaauguucg ucgcacuaaa ccaaaaagga auaccaguaa      600

gaggaaaaaa aacaaaaaaa gaacaaaaaa cagcacacuu ccuaccaaug gcaauaacau      660

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  7283
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt12)

<400>  7283
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacuacuac caagcguagu acuaaaacua uucuuagcag      120

caguacuaag cgcacuagua acaggagaaa gccucgaaag acuacgaaga ggccuagccg      180

cagguacauc aaacccagac ccaccaacag uaucaacaga ccaauuacua ccacuaggag      240

gaggaagaga cagaaaagua agagaccuuc aagaagcaga ccuagaucua cuaagaguua      300

cauuaucauc aaaaccacaa gcacuagcaa caccaaacaa agaagaacac ggaaaaagaa      360

aaaaaaaagg aaaaggacua ggcaaaaaaa gagacccaug cuuaagaaaa uacaaagacu      420

ucugcauaca cggagaaugc aaauacguaa aagaacuaag agcaccauca ugcauaugcc      480

acccaggaua ucacggagaa agaugccacg gauuaagccu accaguagaa aauagacuau      540

acacauacga ccacacaaca auacuagcag uaguagcagu aguacuauca ucaguauguc      600

uacuaguaau aguaggacua uuaauguuca gauaccacag aagaggcgga uacgacguag      660

aaaacgaaga aaaaguaaaa cuaggaauga caaauucaca cuaaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  7284
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt12)

<400>  7284
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uggguuacaa aacuauuacc cgccuuacua uuacagcaug      120

ucuuacuaca ucuauuacua uuacccauag cuauaccaua ugcugaaggc caacguaaaa      180

gaagaaauac aauucaugaa uuuaaaaaau cagcuaaaac aacauuaaua aaaauagacc      240

cagcuuugaa aauaaaaaca aaaaaaguaa acaccgcaga ucaaugugca aaucgaugua      300

cacgaaacaa aggauuaccc uuuacaugua aagcauuugu auuugauaaa gccagaaaac      360

aaugcuugug guuuccuuuc aacucaaugu caucaggagu aaaaaaagaa uuuggccacg      420

aauucgaucu auaugaaaau aaagauuaua uaagaaauug uauaauagga aaaggacgau      480

cauauaaagg aacaguaagu auaacaaaaa gcggaauaaa augucaaccg ugguccagua      540

ugauaccaca ugaacauuca uuuuuaccau caucauaccg agguaaagac uuacaagaaa      600

auuacugcag aaauccacga ggagaagaag gaggaccaug gugcuucaca ucaaauccag      660

aaguucgaua ugaaguaugu gacauuccuc aauguucaga aguagaaugc augacuugua      720

auggagaauc uuauagaggu uuaauggacc auacagaaag uggaaaaaua ugccaacgau      780

gggaucacca aacaccacau agacacaaau uccuaccaga aagauaccca gacaaaggau      840

uugaugauaa cuacuguagg aacccggaug gacaaccaag gccauggugc uauacauuag      900

auccacauac cagaugggaa uauugugcaa uaaaaacuug ugcagauaau acaaugaaug      960

acaccgaugu accacuugaa accacagaau guauacaagg ucaaggagaa ggauaucgag     1020

gaacaguaaa uacaauaugg aauggaauac cgugucaacg augggauagu caauaccccc     1080

augaacauga caugacacca gaaaauuuua aaugcaaaga ucuaagggaa aauuauugua     1140

ggaauccaga uggaucagaa ucaccuuggu guuucaccac agauccaaau auacgcguug     1200

gauauuguuc acaaauacca aauugcgaca ugagucacgg acaggauugc uauagaggua     1260

auggaaaaaa uuauauggga aaccuaucac aaacaagauc aggucuaaca ugcucaaugu     1320

gggacaaaaa cauggaagau uuacauaggc acaucuucug ggaaccagau gcaagcaaau     1380

uaaaugaaaa uuauugucga aauccagaug acgacgcaca uggaccaugg uguuacacag     1440

gaaacccacu aauaccaugg gacuauugcc ccauaucaag augcgaagga gauacuacac     1500

ccacuauagu aaaucuagau cacccuguaa uaucaugugc aaagaccaaa caacucaggg     1560

uaguaaacgg cauaccaacu cgaaccaaua uuggauggau gguuucacua agauaccgca     1620

acaagcauau augcggagga agccuaauua aagaaucaug gguauugaca gcaagacaau     1680

guuucccaag ccgagaccuu aaagauuaug aagcaugguu aggaauacac gacguacaug     1740

gcagaggaga ugaaaaaugc aaacaaguac uuaacguuuc ucaauuaguc uacggaccag     1800

aaggauccga cuuaguacua augaaauuag caagaccagc aguucuagau gauuuuguau     1860

cuacaauaga ucuaccaaac uacggaugua caauaccuga aaaaacaagc ugcaguguau     1920

acggaugggg uuauacuggc cuuauaaauu augacggacu ccuaagggua gcucauuuau     1980

auauaauggg aaaugaaaaa ugcucccaac aucaucgugg aaaaguuaca cuaaaugaau     2040

cagaaauaug cgcaggugca gaaaaaauag guucaggacc augugaggga gauuauggug     2100

gaccauuagu uugugaacaa cauaaaaugc gaaugguccu aggaguaauu guaccaggaa     2160

gaggaugcgc aauaccuaau agacccggaa uuuucgucag aguagcauac uaugcuaaau     2220

ggauacauaa aauaauacua acguauaaag ugccucaauc auaaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  7285
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt12)

<400>  7285
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaaagcag cagccauagg aauagaucuu gguacaacau      120

auucaugcgu aggcguauuu caacauggaa aaguagaaau aauagcaaac gaccaaggca      180

accgaacaac accauccuac guggcuuuca cagacacaga aagacuaauu ggcgaugcag      240

cuaaaaauca aguugcauua aauccacaaa acacaguauu ugacgcaaaa agacucauag      300

gaagaaaauu uggggauccu guaguccaaa gcgauaugaa acacuggccc uuucaaguaa      360

uaaacgacgg cgacaaacca aagguacagg uaaguuauaa gggagaaaca aaagcauuuu      420

accccgaaga aaucagcagc augguauuaa cuaaaaugaa agaaauagcc gaggcauauu      480

uaggauaucc aguuacaaac gcagucauaa cuguaccagc auacuuuaau gauucacaaa      540

ggcaagcaac aaaagaugca ggaguaauag cuggauuaaa cguauuaaga auaauaaacg      600

aaccaacagc agcagcaaua gcguaugguu uagaccgaac aggcaaagga gagagaaacg      660

uacuaaucuu ugaucuagga ggaggaacau ucgauguauc aauauuaaca aucgaugacg      720

gaauauucga aguuaaagca acugcaggag acacacacuu aggaggagaa gauuuugaua      780

acagauuagu aaaccacuuu guagaagaau uuaaacgaaa acauaagaaa gacauuucac      840

aaaauaaaag ggcuguaaga agacuaagaa cagcuugcga aagagcuaaa agaacacuaa      900

gcagcucaac acaagcaagu cuagaaauag acaguuuauu ugaaggaauc gauuucuaca      960

caucaauaac aagagcacga uuugaagaac uauguaguga ccuauuuaga agcacucuag     1020

agccugucga aaaagcauua agagaugcua aauuagacaa agcacaaaua cacgaucuag     1080

uucuaguagg aggaucaacu cgaaucccca aaguacaaaa acuauuacaa gauuucuuca     1140

augguagaga ccucaauaaa aguauuaauc cagaugaagc agucgcauau ggugcugcag     1200

uacaggccgc aauuuuaaug ggggauaaau ccgaaaacgu ccaagaucua uuauuauuag     1260

acguagcacc auuaucacua gguuuagaaa cagcuggagg gguaaugacu gcauuaauaa     1320

aaaggaacag uacaauaccg acaaaacaaa cacaaauauu uacaacauac ucagauaauc     1380

aaccaggagu uuuaauucaa guauacgagg gagaacgcgc aaugacaaaa gacaacaauc     1440

ucuuaggccg guuugaacua ucagguauac cuccagcccc uagagguguu ccacaaauag     1500

aaguaacauu ugauauugac gcuaauggua uccuaaacgu cacagcaacu gacaaaucaa     1560

ccggaaaagc aaauaaaauc acaauaacaa augauaaggg aagacuuagu aaagaagaaa     1620

ucgaaagaau gguacaagag gcagaaaaau auaaagcgga agacgaagua caaagagaaa     1680

gaguaagugc uaaaaacgcg cuugaauccu augcauucaa uaugaaauca gcagucgagg     1740

acgaaggauu aaaaggaaaa auaagugaag cagacaaaaa gaaaguuuua gauaaaugcc     1800

aagaaguuau uucaugguua gaugcaaaua cauuagcaga aaaagacgag uucgaacaua     1860

aaaggaaaga acuagaacaa guauguaauc cuauaauaag cggauuauac caaggugcgg     1920

gagguccagg acccgguggu uucggugcuc aaggaccuaa aggcggcagu ggaaguggac     1980

caacuauaga agaaguagau uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7286
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt12)

<400>  7286
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuaaagcag cagcaaucgg aaucgauuua gggacaacau      120

acagcugugu aggaguauuc caacacggaa aaguugaaau aauagcaaau gaucagggaa      180

acaggacaac uccuagcuau guugcauuua ccgauaccga acgucucauu ggagaugcgg      240

caaaaaauca gguagcauua aacccccaaa acacaguauu ugacgcuaaa agauuaauag      300

gacgaaaauu cggagauccg guuguacaaa gcgacaugaa acacuggcca uuucaaguaa      360

uaaaugaugg agacaaacca aaaguccaag ucucuuacaa aggagaaaca aaagcauucu      420

acccagaaga aauaucaagu auggucuuaa ccaaaaugaa agaaauagca gaagcauacu      480

uaggguaccc aguaacaaau gcaguaauaa caguucccgc auauuuuaac gauagccaaa      540

gacaagcuac uaaagacgca ggaguaaucg caggauuaaa uguacuuaga auuauaaaug      600

agccaacugc agcagcaauu gcauauggau uggacaggac uggaaaagga gaaagaaacg      660

uauuaauauu ugaccuagga ggaggcacau uugacguauc aauauuaacc auagacgacg      720

gaauauucga gguaaaagca acagcaggag acacccauuu aggaggagaa gauuucgaua      780

aucgauuagu aaaucauuuu guagaagaau uuaaaagaaa acauaaaaaa gauauaucac      840

aaaauaaaag agcaguuaga cgauuacgaa cagcuugcga aagagcaaaa agaacccuaa      900

guucuagcac acaagcuagc cuugaaauug auucccuauu ugaaggcaua gauuucuaua      960

caagcaucac ucgagcaaga uuugaagaau uaugcaguga cuuauuuaga ucaacucuag     1020

aaccuguaga aaaagcgcuu agagacgcca aauuagauaa agcacaaauc caugauuuag     1080

ucuuaguagg aggaucaacc agaauaccca aaguacaaaa acuauuacaa gacuucuuca     1140

acggaagaga ucuaaauaaa ucaauaaauc cugacgaggc aguugccuac ggagccgcgg     1200

uacaagcagc aauacuaaug ggagacaaaa gcgaaaacgu acaagaucua uuacuucuag     1260

auguagcacc ucuaaguuua ggauuagaaa cagcaggagg aguaaugacc gcacuaauaa     1320

aaaggaauuc aacgauacca acaaaacaaa cucaaauuuu cacaacauac ucagacaauc     1380

aaccuggagu acuaauacaa guauacgaag gagagagagc aaugacaaaa gauaacaauc     1440

uauugggaag auucgaacua ucaggaauac ccccggcgcc acgaggagua ccgcaaauug     1500

aaguaacuuu ugauauagau gccaauggaa uauuaaaugu aaccgcaacc gauaaaagca     1560

cuggaaaagc aaauaaaaua acaauaacaa augacaaagg aagacuauca aaagaagaaa     1620

uagaacgaau gguccaagaa gcagaaaaau acaaagcaga agacgaagua caacgagaac     1680

gaguuucagc caaaaaugca uuagaaucau acgcauuuaa caugaaaagu gcaguagaag     1740

acgaaggacu aaaaggaaaa aucucagaag cagauaaaaa aaaaguacug gauaaauguc     1800

aagaagucau aaguugguua gacgcaaaua cauuagcaga aaaagacgaa uucgaacaca     1860

aaagaaaaga gcuagaacaa gucuguaacc cuauaauaag uggacuauac caaggagcgg     1920

gaggaccagg accaggaggu uuuggugcac aagguccaaa aggcggaagc ggcagcggac     1980

cuacaauaga agaaguagau uagggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7287
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt12)

<400>  7287
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuacagcaa aaggaauagc uauuggaaua gaucuaggca      120

caacauacag uugcguuggc guuuuucagc auggaaaagu agaaauuaua gcaaaugauc      180

aaggaaaucg caccacuccu ucuuauguag cuuucacaga uacagaacga cuuauaggag      240

acgcugcuaa aaaccaaguu gcaaugaacc cacaaaauac ugucuuugac gcaaaaagac      300

uaauaggccg aaaauucaau gacccaguag uacaagcgga caugaaacuu uggccauucc      360

aagugaucaa cgaagguggu aaaccaaaag uauuaguauc auacaaagga gaaaauaaag      420

cauuuuaccc agaagaaaua agcucuaugg uacugacuaa auuaaaagaa acagcagaag      480

cauuucuagg acacccagua acaaaugcag uaauaacagu acccgcuuac uuuaaugacu      540

cccaaagaca agcaacaaag gacgcaggag uuauagcagg acuuaaugua cuuagaauaa      600

ucaacgaacc aacagcggca gcaauagccu auggauuaga uaaaggagga caaggagaac      660

gacauguauu aauauuugac cuagguggag guacauucga ugucucuaua uuaaccauag      720

acgacggaau auucgaagua aaagcaacag caggggacac ucauuuaggc ggagaagauu      780

uugacaauag auuaguaagc cacuucguag aagaguucaa aagaaaacac aaaaaggaua      840

uaagucagaa uaaacgagca guaagaagac uacgaacagc cugugaaaga gcuaaaagaa      900

cguuaucaag uucaacacaa gcaaaucuag aaauagacag ucuauaugaa ggaauagauu      960

ucuauaccuc aauaacgaga gcuagauuug aagaacuaug cgcagaucua uucagaggca     1020

cacuagaacc aguagaaaaa gcucuacgag augcaaaaau ggacaaagcu aaaauucaug     1080

auauaguccu uguaggggga ucaacaagaa uaccaaaagu acaaagauug uuacaagauu     1140

acuuuaacgg aagagauuua aacaaaucaa uaaacccaga ugaagcugua gcauauggcg     1200

cagcaguaca agcagcaaua cuuaugggag auaaaaguga aaaaguacaa gauuuauuau     1260

uauuagacgu agcaccacua ucccuaggac uagaaacagc aggaggagua augacagcac     1320

ucauaaaaag aaauaguacc auaccaacaa aacaaaccca aauauuuaca acguauagcg     1380

acaaucaacc aggaguacua auacaagugu augaaggaga aagagcaaug accaaagaua     1440

auaaucuucu uggccgauuc gaucucacag gaauaccucc agcaccaaga ggagucccac     1500

aaauugaagu uacauuugac auagacgcca augguauacu aaacguaaca gcuaccgaua     1560

aaaguacagg aaaaguaaac aaaaucacaa ucacaaauga caaagguaga uuaucaaaag     1620

aggaaaucga aagaauggua uuggacgcag aaaaauauaa agcagaagac gaaguacaaa     1680

gagagaaaau agcagcuaaa aacgcucuug aaucauaugc auuuaacaug aaaucaguag     1740

uauccgacga aggacucaaa ggaaaaauaa gcgaaucaga uaaaaauaaa auacucgaua     1800

aaugcaacga acuauuaagc ugguuagaag uaaaucaacu agcagaaaaa gaugaauuug     1860

accauaaaag aaaagaacua gaacaaaugu guaauccaau aauaacuaaa uuauaccaag     1920

gaggaugcac aggaccagcc uguggcacag gauauguucc uggacgaccc gcaacuggac     1980

caacaauaga agaaguugau uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7288
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt12)

<400>  7288
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcgcaagag gaccagcgau uggaaucgau cuaggaacaa      120

cguacaguug cgugggagua uuccaacaug gaaaaguuga aauaaucgca aaugaucagg      180

gaaauagaac uacaccauca uacguugcuu uuacagacac cgaaagauug auuggagacg      240

cagcgaaaaa ucaaguagca augaauccaa ccaacacaau cuuugacgca aaaagacuca      300

uaggcagaaa auucgaagac gcaacgguac agagcgauau gaaacacugg ccauuuagag      360

uaguaucaga aggaggaaaa ccaaaaguac aagucgaaua uaaaggagaa acuaaaacau      420

uuuucccaga agaaauaagc aguaugguau uaacaaaaau gaaagaaaua gcagaagcau      480

aucuaggagg aaaaguucau agugcaguaa uaacuguacc agcauauuuu aaugauucac      540

aaagacaagc cacgaaagau gccggaacaa uaaccggauu aaauguacug agaauaauaa      600

acgaaccaac agcugccgca auagcauacg ggcuagauaa gaaaggaugu gccggaggug      660

agaaaaaugu auuaauauuu gacuuaggcg gaggaacauu ugauguauca auacuaacaa      720

uugaagacgg aauauucgaa guuaaaagua cggcgggaga uacacauuua ggaggagaag      780

auuuugauaa cagaauggua agucauuuag cagaagaguu caaacgaaaa cacaagaaag      840

acauaggacc uaauaaaaga gcaguaagaa gacuaaggac ugcaugcgaa agagcaaaaa      900

gaacacuaag uagcaguaca caggcgagua uagaaauaga cucauuauau gaaggagucg      960

auuuuuauac uucaauaacg agagcaagau ucgaagaacu caaugcggau uuauuuagag     1020

gaacauugga accaguagaa aaagcacuua gagaugcaaa acuagacaaa ggacaaaucc     1080

aagaaauagu ccuaguaggu ggcucaacaa gaauaccaaa aauccaaaaa cuauugcaag     1140

auuucuucaa uggcaaagaa uuaaauaagu caaucaaucc agacgaagca gucgcauacg     1200

gagcagcagu ucaagcagca auauugauag gggauaaauc agaaaaugua caagaccuau     1260

uauuguuaga uguaacacca uuaagucucg guauagaaac ugcaggagga guaaugacac     1320

cucuaauaaa aagaaacaca acuauaccaa caaaacaaac acaaacauuu acaacauaca     1380

gugacaauca aucaagugua uuaguacaag uauacgaagg agaaagagca augacgaaag     1440

acaacaaucu auuaggaaaa uuugaucuaa cagggauucc uccagcaccg agagguguac     1500

cacaaaucga aguaacauuu gacauagacg caaauggaau auuaaacgua acagcagcag     1560

auaaaucaac cgggaaagaa aacaaaauca caauaacuaa cgauaaaggg agguuaagca     1620

aagaugauau cgaucguaug guccaagaag cagaaagaua uaaaagcgag gaugaggcaa     1680

acagagacag aguagcagcg aaaaaugcau uagaaucuua cacguauaau auaaaacaaa     1740

cuguagagga cgaaaaauua cggggaaaaa uauccgaaca agauaaaaac aaaauauuag     1800

auaaaugcca agaagucaua aacugguuag acagaaauca aauggcagaa aaagaugaau     1860

acgaacauaa acagaaagaa cuagaaagag uguguaaucc cauaauauca aaauuauacc     1920

aaggaggucc aggaggugga agcgggggag gaggaagugg cgcaagcgga gggccaacaa     1980

uagaagaagu agauuaggga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7289
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt12)

<400>  7289
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucuguaguag gaauagaccu cggauuucaa aguuguuaug      120

uagcagucgc ucgggcagga ggcauugaaa caauugcaaa ugaauacuca gacaggugua      180

caccagcaug cauaaguuuc ggaccaaaaa accgaucaau aggcgcagca gcaaaaagcc      240

agguaauauc aaaugcuaaa aauacaguac aaggguuuaa aagauuccac ggaagagcau      300

uuucagaucc uuuuguagaa gcugaaaaaa guaauuuagc cuacgacaua guucaguuac      360

caacaggauu aacaggcaua aaaguaacuu auauggaaga agaacgaaac uuuacaacug      420

aacaaguaac agcaaugcua cuaucuaaau uaaaagaaac ugcagaaagu guuuuaaaaa      480

aaccaguagu agacugugua guaagcgugc cauguuuuua uacagacgcg gaaagaagau      540

cggucaugga ugcaacacaa auagcagggc ucaauugccu uaggcucaug aaugaaacaa      600

cugcaguagc ucuagcuuac ggaauuuaua aacaagacuu gccagcacua gaagagaaac      660

caagaaacgu cguuuucguc gauaugggac acucagcaua ccaaguaagu guuugcgcau      720

uuaauagagg aaaacuaaaa guauuggcaa cagcauuuga cacaacacua ggagguagaa      780

aauucgauga aguacuaguc aaucacuuuu gugaagaauu cggaaaaaag uacaaacuag      840

auauuaaauc aaaaauuaga gcauuauugc gacuaagcca agaaugugaa aaacuaaaaa      900

aauuaauguc agcaaaugca ucugacuuac cauuaagcau ugaaugcuuu augaaugaug      960

uagaugucuc aggaacaaug aaucgaggaa aauucuuaga aauguguaac gaucuacuag     1020

cuagagucga acccccucuc aggucagugc uagaacaaac aaaacuaaaa aaagaagaua     1080

uauacgccgu ggaaaucgua gguggagcua ccagaauacc agcugugaaa gagaaaauaa     1140

guaaauucuu cggcaaagaa uuaucaacaa cacuaaaugc agacgaagca guuacccgag     1200

gaugugcuuu acaaugugca auuuuaucgc cagcauucaa aguacgagaa uucucaauaa     1260

cagauguagu accuuauccc auaucucuua gauggaauuc accagcagaa gagggaagcu     1320

cagauugcga aguauuuuca aaaaaccacg cugcaccguu uuccaaagua cugacuuucu     1380

acagaaaaga accauuuacg uuagaagcau acuauucauc uccccaagac uuaccauacc     1440

cagaucccgc cauugcacaa uucucaguac aaaaggugac cccacaaucc gacggaucca     1500

gcucaaaagu gaaaguaaag guaagaguaa auguacacgg cauauuuuca guaaguucag     1560

cgucccucgu agaaguucac aaaagcgaag aaaacgaaga accaauggaa acagaccaaa     1620

acgcaaaaga agaagaaaaa augcaaguag accaagaaga accccaugua gaagaacaac     1680

aacaacaaac acccgcagaa aacaaagccg aaagugaaga aauggaaaca ucacaagcag     1740

gcaguaaaga uaagaaaaug gaucaaccac cacaggcaaa aaaagcuaaa guaaaaacaa     1800

guacaguaga ucucccaauu gaaaaucaac uacuauggca aaucgauaga gagauguuaa     1860

accuauacau cgaaaaugaa ggaaaaauga ucaugcaaga caaacuagaa aaagaacgga     1920

acgaugcaaa aaacgcagug gaagaguaug uauaugaaau gcgagacaaa cuaucaggag     1980

aauaugaaaa auuuguuagc gaggaugaca gaaauucauu caccuuaaaa cuagaagaua     2040

cugaaaauug guuauaugaa gacggagaag accaaccuaa gcaaguguac guugauaagc     2100

uagcagagcu caaaaauuug ggccagccaa uaaaaauaag auuccaagaa uccgaagaaa     2160

gaccgaaacu auucgaagaa cuugggaaac aaauacagca auacaugaag auaaucucau     2220

cauuuaaaaa caaagaagau caauacgacc acuuagacgc agcagacaug acuaaaguag     2280

aaaaaucuac gaacgaagca auggaaugga ugaauaacaa acuaaaucuu caaaacaaac     2340

aaucacuuac aauggaccca guaguaaaaa gcaaagaaau cgaagcgaaa auaaaagaau     2400

uaacgagcac auguucaccu auaauaucaa aaccaaaacc aaaaguggaa ccaccuaaag     2460

aagaacaaaa aaaugcagaa caaaauggac cgguagacgg gcaaggagac aauccaggac     2520

cucaagcagc cgaacagggc acagacacag caguaccauc agacagcgac aaaaaacuac     2580

cggaaaugga cauagacuga ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  7290
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt12)

<400>  7290
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agugugguag gaauagaccu uggauuccua aauugcuaca      120

uagcuguagc aagaucagga ggcauugaaa caauagcaaa cgaauauagc gaccgaugca      180

caccagcaug cauaucauua ggaaguagga cuagagccau agguaaugcg gcaaaaucac      240

aaauaguaac caauguaaga aacaccauac auggauucaa gaaacuacac ggacgcagcu      300

ucgacgaucc aauaguacaa acagaaagaa uuagacuacc cuacgaacua cagaaaaugc      360

caaacggauc ugcaggaguc aaaguaagau accuugaaga agaacggcca uuugcaauug      420

aacaagugac aggaauguua cuugcaaaac uaaaagaaac aagugaaaau gcauuaaaga      480

aaccaguagc agauugcgua auuucaauac ccagcuucuu cacagacgca gaaagaagaa      540

guguaauggc agcagcacaa guagccggac uaaacugucu aagacuaaug aacgaaacaa      600

cagcuguagc uuuagcauac ggcauauaua aacaagaucu accaccacua gaugaaaaac      660

caagaaacgu aguuuuuaua gauaugggac acucagccua ccaaguccua guaugugcuu      720

ucaacaaagg aaaauuaaaa guacuugcaa caacauuuga uccauaucua ggggguagaa      780

auuucgacga agcucuagua gacuacuuuu gugaugaguu caaaacaaaa uacaaaauua      840

augucaaaga aaauucaaga gcauuacuca gacuuuacca agaaugcgaa aaauuaaaga      900

aacuaauguc ugcaaaugca uccgauuuac cgcuaaauau cgaaugcuuu augaaugauc      960

uugacguauc aagcaaaaug aacagagcac aauuugaaca acuaugugca uccuuauuag     1020

caagaguaga accuccccua aaagcgguaa uggaacaagc uaaucuccaa cgcgaagaca     1080

uaagcucaau agaaauagua ggcggagcaa ccagaauacc ggcagugaaa gaacaaauaa     1140

caaaauuuuu cuuaaaagac auuucuacaa cuuuaaacgc agacgaagcu guggcuagag     1200

guugcgcacu ucaaugcgcc aucuuaucac cagcguucaa aguccgcgag uucaguauaa     1260

cagaccuggu accauacagu aucacgcucc gauggaaaac uagcuuugaa gacggcucug     1320

gggaaugcga aguauucugu aaaaaucacc cagcaccauu uagcaaagua auaacauuuc     1380

acaagaaaga accauucgaa cuagaagcau ucuacacaaa cuuacaugaa guucccuacc     1440

cagaugcacg aauagguagu uucacaauac aaaauguauu cccacaaucc gacggagacu     1500

caucuaaagu caaagucaaa gugcggguaa acauacaugg aauauucucc guugcaagug     1560

caagugugau agaaaaacaa aaccucgaag gggaucauuc agacgcaccu auggaaacgg     1620

aaacaaguuu caaaaacgaa aacaaagaua auauggacaa aaugcaagua gaucaagaag     1680

aaggacacca aaaaugccau gcggaacaua cucccgaaga agaaauagau cauacaggug     1740

cuaaaacaaa aucagcagua uccgacaaac aagacaggcu aaaucaaaca cucaagaaag     1800

gaaaaguaaa aaguauagac cugccgauac aaagcagucu cugucgacaa uuaggacaag     1860

auuuacuaaa uaguuacaua gaaaaugaag ggaaaaugau uaugcaagau aaauuagaaa     1920

aagaaaggaa cgaugccaaa aaugcuguug aagaauacgu auaugacuuu cgcgacagau     1980

uaggaacagu auacgaaaaa uuuauaaccc ccgaagaccu aaguaaacua ucugcaguac     2040

uagaagacac agaaaauugg uuauaugaag auggagaaga ucagccaaaa caaguuuacg     2100

uagauaaacu acaagagcuu aagaaauacg gacaaccaau ucaaaugaaa uauauggaac     2160

augaagaacg cccgaaagca uuaaacgacu uaggaaagaa aauacaauua guaaugaaag     2220

uaauagaggc cuacagaaac aaagaugaaa gguaugacca ccucgauccc acagaaaugg     2280

aaaaaguuga aaaaugcaua ucagacgcua ugucauggcu aaacagcaaa augaacgccc     2340

aaaacaaauu aucacuuacu caggauccug uaguaaaagu aagcgaaaua guagcgaaaa     2400

gcaaagaacu agacaacuuu uguaacccua uaaucuauaa accuaaaccc aaagcagaag     2460

uaccagagga uaaacccaaa gccaauucug aacauaaugg gccaauggau ggacaauccg     2520

gcacagaaac aaaaucggac aguaccaaag acucaucaca gcacacaaaa agcaguggag     2580

aaauggaagu ugacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  7291
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt12)

<400>  7291
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaacucucac uaguagcagc gauguuauua cuuuuaagug      120

cugcacgagc agaggaagaa gauaaaaaag aagacguagg uacaguagua gguauagacc      180

uaggaacaac auacucaugu guaggaguau ucaagaaugg acgaguagaa auuauagcaa      240

augaucaagg caauagaaua acaccaaguu auguagcuuu cacacccgaa ggagaaagau      300

uaauagggga cgcagcuaaa aaccaauuaa caagcaaucc agagaacaca guauuugacg      360

caaaaagauu aaucggcaga acauggaaug accccucugu acaacaagau auuaaauuuc      420

uaccguuuaa agugguagaa aaaaaaacaa aaccuuauau acaaguagac auaggaggag      480

gacaaacgaa aacauucgcu ccagaagaaa uaagcgcaau gguuuuaacu aaaaugaaag      540

aaacagcgga agcauauuua ggaaaaaaag uaacucacgc uguaguaaca gucccagcau      600

acuuuaacga ugcucaaaga caagccacaa aagaugcagg aacaauugca ggcuuaaaug      660

uaaugagaau aauaaaugaa ccuacagcag ccgcaauagc guacggacua gacaaaagag      720

aaggcgaaaa aaacauacua guauuugauu uaggaggagg aacauucgau guaagucuac      780

uuacaauuga caacggaguc uuugaaguag uagccacaaa uggagauacg caucuaggag      840

gagaggacuu cgaccaaagg guuauggaac acuucauaaa auuauacaaa aaaaaaacag      900

gaaaagacgu uagaaaagac aauagagccg uacaaaaauu aagacgagag guagaaaaag      960

caaaaagagc auugucaagc caacaccaag caagaauaga aauagaauca uuuuaugaag     1020

gagaggacuu cagcgaaaca cuuacaagag caaaauuuga agaacugaau auggauuuau     1080

uuagaaguac aaugaaacca guucaaaaag ucuuagaaga uagugauuua aaaaaaagcg     1140

acauagauga aauaguacuc guaggaggau caacaaggau accaaaaaua caacaauuag     1200

uuaaagaguu uuuuaaugga aaagaaccau cacgaggaau aaauccagac gaagcaguag     1260

cauacggagc agcaguacag gcaggaguac uaagcggaga ucaagauaca ggagaucuag     1320

ucuuacuaga ugucugccca cuuacauuag gaaucgaaac cguaggaggg guaaugacaa     1380

aacuaauacc acguaacacg guugugccaa caaaaaaauc acagauauuc aguacagcgu     1440

cagacaauca gccaaccguc acuauaaaag uauacgaagg agaacgacca cuuacaaaag     1500

auaaccaucu acuaggaacc uucgauuuaa caggaauacc acccgcccca agaggaguac     1560

cacaaauaga aguuacauuc gaaauagacg uaaacgguau ucuuagagug acagcugaag     1620

acaaaggaac cggaaauaaa aauaaaauaa caauaacuaa cgaucaaaac cgacuaacuc     1680

cagaagaaau agaacgcaug guaaacgaug cagaaaaauu ugcagaagaa gacaaaaaac     1740

uaaaagaacg aaucgauacu agaaaugaac uagaaucaua cgcauauuca uuaaaaaauc     1800

aaauaggcga caaagaaaaa cuaggaggaa aauuaucaag ugaggauaaa gaaacuaugg     1860

aaaaagcggu cgaagaaaaa auagaguggu uagaaaguca ucaagacgcu gauauagaag     1920

auuuuaaagc aaaaaaaaaa gaauuagaag agauaguaca accaauaaua ucaaaacuau     1980

auggaagcgc cgguccucca ccaacaggcg aagaagacac agcugaaaaa gacgaauuau     2040

gaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  7292
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt12)

<400>  7292
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagccccaa gagaauuagc aguuggaaua gaccuaggua      120

caacauacuc auguguagga guuuuucaac aaggaagagu ugagauacua gcaaaugauc      180

aaggaaacag aacaacaccc agcuauguag cauucacuga cacagaaaga uuagucggag      240

acgccgcaaa aucacaagca gcucuaaacc cucauaauac aguuuuugau gcuaaaaggc      300

uuauagggag aaaauucgca gacacaacag uacaaucaga uaugaaacac uggcccuuuc      360

gaguaguauc agaaggagga aaaccgaaag uaagaguuug cuauagagga gaagauaaaa      420

cauuuuaccc agaagaaauc ucaucaaugg uucuuaguaa gaugaaagag acagcggaag      480

cauacuuagg acaaccgguc aaacacgccg uuauaacagu accugcauau uucaaugaca      540

gucaaagaca agcuacaaaa gaugcaggag caauagcagg auuaaaugua uuaagaauua      600

uuaaugaacc aacagccgca gcaauagcau acggacuaga ucguagagga gccggagaaa      660

gaaacgucuu aauauuugau uuaggagggg gaacauuuga uguaucaguu cuaucgauag      720

augcaggagu auuugaagua aaagcuacag caggagauac acauuuaggc ggggaagauu      780

uugauaacag auuaguaaau cacuucaugg aagaauuuag aagaaaacac gguaaggacu      840

uaucaggaaa uaaacgagca cucagaagac uuagaacagc cugugaacga gcaaaacgua      900

cuuugagcuc aaguacacaa gcuacuuuag aaauagacag uuuauucgaa gguguugauu      960

uuuacacaag uauuacuaga gcaagauuug aagaacuaug uucagauuua uuucguucaa     1020

cauuagaacc aguagaaaaa gcacuaagag augcaaaacu agauaaagcu caaauacaug     1080

auguggugcu aguaggaggu uccacaagga ucccaaaagu ccaaaaacua cuacaagauu     1140

ucuuuaaugg caaagaacuc aacaaaagua uaaaucccga ugaagcagua gcauauggug     1200

cagcaguaca agcagcaguu uuaaugggag auaaguguga aaaaguacaa gauuuacuau     1260

uacuagacgu agcaccccua ucacucggac uagaaacagc uggaggagua augacuacac     1320

uaauucaaag aaacgccaca aucccaacaa aacaaacaca aacauuuaca acauacucag     1380

auaaucaacc aggcguauuu auacagguuu acgaagguga acgagcaaug accaaagaca     1440

auaaucuacu cgguagauuc gaacuaagug gaauaccacc agccccaaga ggaguaccac     1500

aaauagaagu aacauuugau auagaugcaa augguauucu cagcguaacu gcaaccgacc     1560

guagcacagg aaaagcuaac aaaauaacua uaacgaauga uaaaggaaga cuaaguaaag     1620

aagaaguaga acgcauggua caugaagcag aacaauauaa agcagaagac gaagcacaaa     1680

gagauagagu ugcagcuaaa aacaguuuag aagcacaugu guuccaugua aaaggaucau     1740

uacaagaaga aucauuaaga gauaaaauuc cagaagaaga uagacgaaaa augcaagaua     1800

aaugcagaga aguacucgca uggcuagagc acaaucaauu agcagagaaa gaggaauaug     1860

aacaccagaa acgagaauua gaacaaauuu gucgaccaau auuuaguagg uuauacggag     1920

gaccaggagu cccaggaggu ucaucaugug gaacccaagc aagacaagga gaucccagua     1980

cagguccaau aauagaagaa guugacuaag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  7293
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt12)

<400>  7293
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcuccaa gagaacuagc uguaggaaua gauuuaggaa      120

caacauauag uuguguagga guauuucaac aaggaagagu ugaaauacua gcaaaugauc      180

aagggaauag gacaacacca ucauauguag cauuuacaga uacagaacga uuaguaggag      240

augcagcaaa aucacaggca gcucuaaacc cacauaauac aguauuugau gcaaaaagac      300

uaauagguag aaaauuugca gacacuacag uacaaagcga uaugaaacau uggccauuuc      360

aaguaguauc agaagguggc aaaccaaaag ucagaguaug uuauagagga gaagauaaaa      420

cuuuuuaucc cgaagaaaua ucaucaaugg uauuaaguaa aaugaaagaa acagcagaag      480

cauaucuagg acaaccagua aaacaugcgg uaauaacagu uccaacauau uuuucaaacu      540

cacaaagaca agcaacaaaa gaugccggug caaucgcagg acuuaaagua uuaccaauaa      600

uuaaugaagc aacagcagca gcaauagcau auggacuaga uagaagagga gcuggaaaaa      660

gaaauguauu aauauucgau uuaggaggug gaaccuuuga uguaucagua uuaagcauag      720

augcaggagu auuugaaguc aaagcaacag caggagauac acaucuagga ggggaagauu      780

ucgauaauag auuaguaaau cacuuuaugg aagaguuuag aagaaaacau ggaaaagauu      840

uaagcgguaa uaaaagagca uuaagaagac uaagaacagc augcgaaaga gcaaaaagaa      900

caccaucaag caguacgcaa gcaacauuag aaauagacuc auuauucgaa ggaguagacu      960

uuuauaaauc aauaacaaga gcgagauucg aagaauuaug cucagacuua uucagaagua     1020

cacuagaacc aguagaaaaa gcauuaagag augcaaaacu ugacaaagca caaauacaug     1080

auuucguacu aggaggagga uuacacaguc auccacaagg agcugaagua gcagcaggac     1140

uauuacaacg acaaggugca gaacaagaac aucaaccaua gggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  7294
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt12)

<400>  7294
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaaaagguc cggcaguagg aaucgauuua ggaacaacau      120

auaguugugu cggaguauuu caacauggaa aaguugaaau aauagcaaac gaucaaggca      180

auagaacuac accaucuuac guugcauuua cagauacaga aagauuaaua ggggacgcag      240

cuaaaaacca aguagcaaug aacccaacaa auacaguauu ugacgcaaaa cgacuaauag      300

gaagaagauu ugaugaugcc guuguacaau cugacaugaa acauuggccc uuuaugguag      360

uaaaugacgc aggaagacca aaaguccaag ucgaauacaa aggagaaaca aagagcuuuu      420

acccugaaga aguuucuagc augguccuaa caaaaaugaa agaaauugca gaagcguacc      480

uaggcaaaac cguaacaaac gcagucguga caguaccagc auauuuuaac gauucacaaa      540

gacaggcaac aaaagacgca ggaacaauug caggacucaa cguacuccga auaauaaaug      600

aaccaacugc ugcagcaauc gcauaugggu uagacaagaa aguaggagca gagcgcaaug      660

uacuaauauu ugaccuagga ggagguacgu ucgauguaag cauauuaaca auagaagaug      720

gcauauuuga aguaaaaucc acagcaggag acacacacuu aggaggagaa gauuuugaca      780

auagaauggu caaccauuuc auugcagagu ucaaaagaaa acacaagaaa gauauuucag      840

aaaauaaaag agcaguaaga agauuaagaa cagcuuguga aagagcuaaa agaacuuuau      900

caucaucaac acaagcuagc auagaaauug acaguuuaua ugaaggaaua gauuucuaua      960

cauccaucac gcgagcaagg uuugaagaau uaaaugcaga cuuauuucga ggaacacuug     1020

acccuguuga aaaagcccua cgagacgcua aacuagacaa aagccaaaua caugacauag     1080

uucuaguagg aggaagcacu agaauaccca aaauacaaaa gcuacugcaa gacuucuuca     1140

acggaaagga acucaacaaa agcauuaauc ccgaugaagc aguagcuuac ggagcugcag     1200

uacaagcugc aauauuaagu ggagacaaaa gcgaaaacgu acaagaucua cuauuacuag     1260

auguaacacc ucuaagccuc ggaauagaaa cggcaggagg agugaugaca guacucauaa     1320

aaagaaauac uacaauacca accaaacaaa cacaaacauu uacaacauac ucagacaauc     1380

aaccaggagu auuaauacaa guauacgaag gagaaagagc caugacaaaa gacaauaauc     1440

uccuaggaaa auucgaauua acaggaauac caccagcacc ucgcggagua ccacaaaucg     1500

aaguaaccuu ugacauugau gcgaacggca uauuaaaugu uucagccguc gacaagucua     1560

caggaaaaga gaacaagaua acaauaacua augauaaagg gcgauuaagc aaagaagaua     1620

uagaacgaau gguacaagaa gcagaaaaau auaaagcaga agaugaaaaa caaagagaua     1680

aaguaucuag caaaaauagc cuagaaaguu augcauucaa uaugaaagcc acaguugaag     1740

acgaaaaauu acaaggcaaa auaaaugacg aagauaaaca gaaaauauua gacaaaugua     1800

acgaaauaau aaacuggcug gauaaaaauc aaacggccga aaaagaagaa uuugaacauc     1860

aacaaaaaga auuagaaaaa guaugcaauc cgauaauaac aaaauuauac caaucagcug     1920

gggguaugcc aggggguaug ccagguggau ucccaggagg gggagcacca ccaagcggag     1980

gagcaagcuc aggaccaaca aucgaagaag ucgacuaagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  7295
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt12)

<400>  7295
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auauccgcau caagagcagc agcggcaaga uuaguaggag      120

cagcagcaag uagaggacca acagcagcaa gacaccaaga caguuggaau gguuuaagcc      180

augaagcauu uagacucgug aguaggagag auuaugcaag ugaagccaua aaaggagcug      240

ugguaggaau agauuuagga acaacuaauu cauguguugc aguaauggaa ggaaaacagg      300

cuaaaguacu agagaaugcg gaaggagcua gaaccacucc caguguagua gcauucacag      360

cugauggaga aagauuggua gggaugccgg caaaaagaca agcaguuacg aacccaaaua      420

acacauuuua ugcaacaaaa cgacuaauag ggaggcgaua cgaugacccg gaaguucaaa      480

aagauauuaa aaacguuccu uuuaagauag uaagagccag caauggagau gccuggguag      540

aagcccacgg aaaguuauau ucaccaaguc aaauaggggc uuuuguacua augaaaauga      600

aagaaacagc cgaaaauuac uuaggacaua cugcuaaaaa ugcaguuaua acaguaccag      660

cauauuuuaa ugauagccaa agacaagcua caaaagaugc aggucagaua aguggucuca      720

acguucugcg cguaauuaau gaaccaacag cugcugcacu agcauacggg uuagauaaaa      780

gugaagauaa agucauagcg guauaugauu uaggaggagg cacauuugau auaucaauau      840

uagaaauaca aaaaggggua uucgaaguua aaagcaccaa uggagauacg uuucuuggag      900

gggaagauuu ugaccaagcg uuauuaagac auauagugaa agaauuuaag agagagacag      960

gaguagaucu aacaaaagac aacauggcau uacaaagagu uagagaagcu gcugagaagg     1020

caaaauguga auuaagcuca aguguacaaa cagauauaaa uuuacccuau uuaacaaugg     1080

auagcagugg accgaaacau cuaaauauga aauugaccag agcucaauuu gaaggaauag     1140

ugacagauuu aauaaggaga acaauagcac caugccagaa agcaaugcaa gaugcagagg     1200

ugaguaaaag cgauaucgga gaagugauau ugguaggagg aaugacaaga augccaaaag     1260

uacaacaaac aguacaagac uuauuuggca gagcaccaag caaagcuguu aacccagaug     1320

aagcaguggc uauuggagca gcuauacaag gaggaguguu agcaggagau guaacagaug     1380

uauuauuacu agauguaaca ccauuaucau uggguauaga aacacuagga gggguauuua     1440

caaagcuaau aaauagaaau acaacaauac caacaaagaa gucucaagua uucucaacug     1500

cagcagaugg gcaaacacaa guagaaauaa aaguauguca aggagaaaga gaaauggcag     1560

gcgacaauaa acuacuugga caauuuacac uaauaggcau accgcccgcc cccaggggag     1620

uuccacaaau agaaguaacc uucgauauag augccaacgg aauaguacac guaagcgcaa     1680

aggacaaagg gacagggaga gaacaacaaa uaguaauaca auccagcgga gguuuaucaa     1740

aagacgacau agaaaacaug guuaaaaaug cagagaagua ugcagaagaa gauagaagaa     1800

agaaagaaag aguagaagca guaaauaugg cagaggguau uauacaugau acggaaacaa     1860

aaauggaaga auuuaaagau caauuaccug cagacgaaug caauaaacua aaagaagaaa     1920

uaagcaaaau gagagaauua cuagcaagaa aagauucgga aacuggagaa aauauaagac     1980

aagcagcuag uagccugcag caagccagcu uaaaacuauu cgagauggca uauaagaaaa     2040

uggcaagcga aagagaaggc agugggagcu caggaacagg ugaacaaaaa gaagaccaaa     2100

aagaagaaaa acaauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  7296
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt12)

<400>  7296
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcugauaaag aagcuggagg uucugaugga ccacgagaaa      120

cagcuccaac uucugcuuac ucaaguccag caaggucuuu aggagacacg ggaauuaccc      180

cguuaagucc cagucauaua gucaacgaua cugauucuaa cguguccgaa caacaaagcu      240

uucuuguagu aguagcaguu gacuucggaa cuacuucauc aggauaugcg uauucauuua      300

caaaagaacc agaauguauc cacgugauga gacgauggga aggaggagau cccggaguaa      360

gcaaucaaaa aacaccgaca acaauacucu uaacaccaga acgaaaauuc cauucauuug      420

gcuacgcagc uagagauuuc uaucaugauc uagauccaaa ugaagcaaaa caaugguuau      480

aucuugaaaa auuuaaaaug aaacuacaua caacagguga ccucacaaug gauacugauc      540

uaacagcagc aaaugggaag aaaguuaaag cacuagaaau auuugcauac gcccuucaau      600

acuuuaaaga acaagcacuu aaagaacuau cagaucaagc aggaucugaa uuugaaaaua      660

gcgauguuag auggguaaua acaguuccag caauauggaa acaaccagca aaacaauuua      720

ugcgccaagc ugcauaccaa gcaggacucg ccucuccaga gaauucagaa caauuaauaa      780

uugcauuaga accugaagca gccaguauau auugcagaaa acuaagauua caucaaauga      840

uugaauuaag uaguaaagca gcaguaaacg guuauagugg uucagauaca guaggagcug      900

gcuuuacuca agcaaaagaa cauauaagaa gaaauagaca aucaaggaca uuuuuaguag      960

aaaauguaau uggugaaaua ugguccgaau uagaagaagg agacaaauau guagucguag     1020

acucuggugg cggaacugua gaccuaacag uacaucaaau aagacuucca gaaggacauc     1080

uaaaagaauu auauaaagca acgggaggcc ccuauggauc auuaggugua gauuaugaau     1140

ucgaaaaauu auuauauaaa auauuuggcg aagauuuuau agaacaauuc aaaauaaaaa     1200

gaccugcggc uuggguagac uuaaugauag cuuuugaauc aagaaaaaga gcugccgccc     1260

cagacagaac aaauccauua aauauaacau uaccauuuuc auuuauugau uauuauaaaa     1320

aauuuagagg acacucugua gaacaugcac uuagaaaaag caacguagau uuuguaaaau     1380

ggaguucuca aggaauguua agaaugucac cagacgcaau gaacgccuug uucaaaccaa     1440

cgauugauag uauaauagaa cacuuacgcg acuuauuuca aaaaccagaa guaucaacag     1500

ucaaauuucu auuuuuaguc ggaggauuug cagaagcacc acuucuacaa caagcaguac     1560

aagcagcauu uggagaucaa ugcagaauca uaauaccuca agacguaggc cucacgauuc     1620

uaaaaggcgc agugcuauuc ggucuagauc cagcaguuau aaaaguucgg cgaucacccu     1680

uaacauaugg aguuggagua uuaaaucgau acguagaagg aaaacaucca ccagaaaaau     1740

uauuaguaaa agacgguacg agauggugua ccgauguauu cgauaaauuu auaucagcag     1800

accaaucagu agcucucggc gaacucguua aaagauccua uacaccagca aaaccaucuc     1860

aauuaguuau aguaauuaau auauauucaa gcgagcacga uaacguuuca uuuauaacag     1920

auccaggugu aaaaaagugc gguacauuaa gacucgacuu aaccggaaca aguggaacag     1980

caguuccagc acgcagagaa auacaaacau uaaugcaauu uggugauacu gaaauaaaag     2040

caacagccau agacauagcc acaucaaaau caguuaaagu uggaauagac uuucuaaauu     2100

acugaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  7297
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt12)

<400>  7297
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uuagcaguac cagaaauggg auuacaggga cuauauauug      120

gaucuucucc agaaagauca ccaguaccau caccacccgg gucaccaaga acccaagaaa      180

gcuguggaau agcuccacua acaccaucac aauccccuaa accagaagua agggcacccc      240

aacaagccag uuucaguguu guaguagcaa uagauuuugg aacuacauca ucagguuacg      300

cauuuuccuu ugcaucagau ccugaagcaa uucauaugau gagaaaaugg gaaggaggag      360

acccuggcgu agcacaucag aaaacuccua cauguuuacu uuugacacca gaaggagcau      420

uucauucauu uggauauaca gcacgagauu auuaucacga cuuagaucca gaagaagcua      480

gagauuggcu cuacuuugaa aaauuuaaaa ugaaaauaca uagugcaaca gaucuaacau      540

uaaaaaccca auuagaagcu guuaauggua aaacuaugcc agcgcuagaa guauuugcgc      600

acgcauuaag auuuuuccga gaacaugcau uacaagaacu uagagaacaa ucaccuucac      660

uaccugaaaa agauacaguu agauggguau ugacuguacc ggcaauaugg aaacaaccag      720

cgaaacaauu uaugagagaa gcugcauauu uagcuggguu aguaucacga gaaaaugcag      780

agcaacucuu aauugcgcuu gagccagaag cagcaucugu cuacugcaga aaauuaagac      840

uacaucaacu acuagauuua aguggcagag cacccggagg uggaagacua ggugagcgaa      900

gaagcauaga uucaaguuuc cgacaagcaa gagagcaacu aagacgauca agacacucaa      960

gaacauuucu aguagaaagc gguguaggag aauuaugggc agaaaugcaa gcaggagauc     1020

gauauguagu ugccgauugc ggggguggca caguagauuu aacaguccau caacuagaac     1080

aaccacacgg aacucuaaaa gaacuauaua aagcaucagg agguccauac ggcgcaguag     1140

gaguggacuu agcguucgaa caacuacuau gcagaauauu uggagaagau uuuauagcga     1200

cauuuaaaag acaaagaccu gcggccuggg uagaucuaac aauagcauuc gaagcaagaa     1260

aacggacggc cgggccgcau agagcaggag cucuaaauau aagccuacca uuuucauuua     1320

uagacuuuua uagaaaacag agaggacaua acguugaaac ugcacugaga cgauccucag     1380

uaaauuucgu aaaauggucu ucacaaggaa uguugcgaau gagcugcgaa gcaaugaaug     1440

aacuauuuca accaacugua aguggcauua uucaacauau agaagcacua uuagcaagac     1500

cugaagucca aggaguuaaa cugcuauucc ugguaggugg auuugcagaa ucggcaguau     1560

uacagcaugc aguacaagca gcuuuaggug caagaggauu acgaguagua guaccacaug     1620

auguaggacu aacaauuuua aaaggagcug uacuauucgg ccaagcucca ggaguuguaa     1680

gaguuagaag aaguccauua accuacgggg uagggguacu uaauagauuc guaccuggac     1740

gacauccacc agaaaaauua uuaguaaggg auggaagacg cugguguaca gauguguucg     1800

aaagauucgu agcugcugaa cagagcguug cucuagggga agaaguacga agaucauacu     1860

guccagcuag accaggccaa aggcgaguau uaauaaauuu auauuguugu gcagcagaag     1920

augcaagauu caucacugau ccaggaguua gaaaaugcgg agcacucucu cuagaguuag     1980

aaccugcgga cuguggacaa gacaccgcag gagccccacc aggaaggaga gaaauacgag     2040

cagcaaugca auuuggugau acagaaauua aagucacugc aguagaugua ucgacaaaua     2100

gaucaguaag agcuucgauu gauuuccuuu cgaauuaagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  7298
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt12)

<400>  7298
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcucgagaaa ugacaauuuu aggaucagcg guauugacac      120

uuuuauuagc aggauaccua gcccaacaau accuaccacu accuacacca aaagugauag      180

gaauagaccu uggaacaaca uacuguucag uaggaguauu cuuuccagga acagguaaag      240

uaaaaguaau accagaugaa aacggacaca uaaguauacc cucaauggua aguuuuaccg      300

auaacgaugu auacguagga uacgaaucag uugaauuagc agacucaaau ccacaaaaca      360

caauauauga cgcaaaaaga uuuaucggaa aaaucuucac agcagaggaa uuagaagcag      420

aaauaggaag auaucccuuc aaaguauuaa auaaaaacgg aaugguagaa uucucuguca      480

caucaaacga aacaauaaca guaagcccag aauacguagg cagucgauua cuacuaaaac      540

ucaaagaaau ggcagaagcg uacuuaggaa ugccaguagc aaaugccgua auaucagucc      600

cagcagaauu cgaucuaaaa caacgaaaca gcaccauaga agcagccaau cuagcaggau      660

uaaaaauacu aagaguaaua aacgaaccaa ccgcagcagc cauggcauau ggacuacaca      720

aagcagaugu auuucacgua uuaguaauug aucuaggagg cggaaccuua gacguaucau      780

uauuaaauaa acaaggagga auguucuuaa cuagagccau gucaggaaau aacaaacuag      840

gaggacaaga uuuuaaccaa cgacucuuac aauacuuaua caaacaaaua uaucaaacau      900

auggauuugu uccuagcaga aaagaagaaa uacauagacu aagacaagcc guagaaaugg      960

uuaaauuaaa ucuuacacuc caccaaagug cacaacuaag cguguuacua acaguagaag     1020

aacaagacag aaaagaacca cacucuucag acacagaauu accaaaggau aaauuaucau     1080

cagcagauga ccaccgagua aauucaggau ucggaagagg acuaucagau aaaaaaucag     1140

gagaaucaca aguucuauuc gaaacagaaa uaucaagaaa acuauuugac acauuaaacg     1200

aagauuuauu ccaaaaaaua cuaguaccaa uacaacaagu acuuaaagaa ggacaucuug     1260

aaaaaacgga aauagacgaa guaguacucg uaggagguuc aacaagaaua ccaagaauaa     1320

gacaaguaau ucaagaauuu uuuggaaaag acccaaauac auccguagau ccagaucuag     1380

ccguaguaac cggcguagcu auacaagcag gaauagaugg uggaucaugg ccauuacaag     1440

uaucagcacu cgaaauccca aacaagcacu uacaaaaaac aaauuucaac uaaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  7299
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt12)

<400>  7299
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagcaaucg gaguucaucu aggauguaca agcgcaugcg      120

uagcaguaua caaagacggu cgagcaggug uugucgcaaa cgaugcagga gauagaguaa      180

caccagcugu aguagcauau agugaaaacg aagaaauagu aggauuagca gcaaaacaaa      240

gcaggauucg aaauauauca aauacaguaa ugaaaguaaa acaaauauua ggccgaagca      300

gcuccgaccc ucaagcacaa aaauauauag cagaaaguaa auguuuagua auagaaaaaa      360

auggaaaacu aagauacgaa auugauacgg gagaagaaac aaaauucgua aauccggaag      420

auguagcaag gcuaauauuu agcaaaauga aagaaacagc ucauagugua uuaggaagcg      480

acgcaaacga cguaguuaua acagucccuu ucgauuuugg agaaaaacaa aaaaaugcuc      540

uuggagaagc cgcaagagca gccggcuuua auguacuaag acuaauacau gaaccaucag      600

cagcucuauu agcauaugga aucggacaag auucaccaac agguaaaagu aacauacuag      660

uauuuaaauu aggaggaaca ucauuaucac uauccguaau ggaaguaaau ucaggaaucu      720

auagaguauu aaguacaaac acagacgaca acauuggagg agcacacuuu acagaaacuu      780

uagcacaaua ucuugcaucc gaauuucaaa gaaguuuuaa acaugacgua agagguaacg      840

caagagcgau gaugaaacug acaaauucag cagaaguagc aaaacauagu cuaucaacau      900

uaggauccgc aaacugcuuu cuagauaguu uauaugaagg acaagacuuu gacugcaaug      960

uaucaagagc acguuucgaa cucuuauguu caccguuauu uaauaaaugc auagaagcaa     1020

uaagaggacu auuagaucaa aauggauuua cagcugauga uauaaauaaa guuguguuau     1080

guggaggauc aucaagaaua ccaaaauuac aacaauuaau aaaagauuua uuucccgcag     1140

uagaauuauu aaauucaaua ccaccagacg aaguaauucc aauaggcgca gccaucgaag     1200

caggcauacu aauaggaaaa gaaaaccuau uaguagaaga cucauuaaug auagaauguu     1260

cagcaagaga uauauuagua aaaggaguag augaaagugg ugcgucaagg uuuacaguau     1320

uauuuccaag cggaacacca cuaccugcaa gaagacaaca uacgcuacaa gcaccaggua     1380

guauaaguuc aguaugucua gaacuauaug aauccgacgg aaaaaacagc gcaaaagaag     1440

aaacaaaauu ugcacaaguu guuuuacaag auuuagauaa aaaagaaaac ggcuuaagag     1500

acauuuuagc aguauuaaca augaaacgcg auggaucacu acauguaaca uguacagacc     1560

aagaaacagg aaaaugcgaa gcaauaagua uagaaauagc uucauaagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  7300
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt12)

<400>  7300
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaguaguag gacuugaugu aggaucacaa ucauguuaca      120

uagcaguagc uagagccggu gggauagaaa caauagcaaa cgaauuuagu gauagaugca      180

caccaagugu cauaucauuu gguagcaaaa acagaacaau aggaguagca gcgaaaaacc      240

aacaaauaac ccacgcaaac aacacaguau caaacuucaa aagauuccac ggcagagcau      300

uuaacgaccc cuucauacaa aaagaaaagg aaaacuugag uuaugacuua guaccacuca      360

aaaauggagg aguuggaaua aaaguaaugu acauggggga agaacacuua uuuagcguag      420

aacaaauuac ugcaaugcua uuaacaaaac uuaaagaaac agcagaaaac ucauuaaaga      480

aaccaguaac agauugugua aucuccguac caucuuucuu uacagaugca gaaagacgau      540

ccgucuuaga cgcagcacaa auaguuggcc uaaauuguuu aagguugaug aacgacauga      600

cugccguagc ccuaaauuau gguauuuaca aacaagacuu accaagccuc gaugagaaac      660

cccggauagu aguauuugua gacaugggac acagcgcauu ucaagugagu gccugugccu      720

uuaacaaagg aaaacucaaa guucucggua ccgccuuuga uccguuuuua ggaggcaaaa      780

auuucgacga aaaauuaguc gaacauuuuu gcgcagaauu uaaaacaaaa uauaaauuag      840

acgcgaaaag caaaauaaga gcgcuacuga gauuauacca agaaugugaa aaacuaaaga      900

aacuaaugag uucaaauagu acagaccuac cacuaaauau agaguguuuc augaacgaca      960

aagacguaag cggaaaaaug aauagaucac aguucgaaga acuuugugca gaacuauuac     1020

agaaaauaga aguucccuua uauucauuau uagaacaaac acacuuaaaa guagaggaug     1080

ucucagcugu agaaaucguc ggaggagcca cccguauucc agcggucaaa gaaagaauag     1140

caaaauucuu uggcaaagac auaaguacaa cccuaaacgc cgaugaagca gucgcaagag     1200

gaugugcacu ccaaugugca auccuuaguc cagccuuuaa aguaagagag uuuuccguaa     1260

cugacgcagu accauuuccu auuucucuaa uuuggaauca ugauucagaa gauacagaag     1320

gaguacauga aguauuuuca agaaaccaug cagcaccguu caguaaagua uugacauuuu     1380

ugcgaagagg cccauucgaa cuagaagcau uuuacucaga uccacaaggg guaccauacc     1440

ccgaagcaaa aaucggaaga uuuguuguac aaaacgucuc agcacaaaaa gauggagaga     1500

aaagcagagu aaaaguaaaa guacgaguaa acacucaugg aauauucaca auaucuaccg     1560

caagcauggu agaaaaaguc ccaacagaag aaaacgaaau gucaagcgaa gccgauaugg     1620

aaugcuugaa ucaacgaccg cccgaaaacc cagauacuga caaaaacgua caacaagaua     1680

auucagaagc uggaacucaa ccacagguac aaaccgaugc acaacaaacc ucacaaagcc     1740

caccaagucc cgaacuuacg uccgaagaaa acaaaauacc agacgcagau aaagcaaacg     1800

agaagaaagu cgaccaacca ccagaagcaa agaaaccgaa aauaaaagua gugaauguag     1860

aauuaccaau agaagccaac cuaguguggc aacuaggaaa agaccuccua aacauguaca     1920

uugaaacaga aggaaaaaug auaaugcaag auaaauugga gaaagaaaga aacgacgcca     1980

aaaaugcagu agaagaauac gucuacgagu ucagagauaa acuauguggu ccauaugaaa     2040

aauucauaug ugaacaagau caccaaaauu uccuuagauu acuuacagaa acugaagauu     2100

gguuauauga agaaggcgaa gaucaagcaa aacaagccua cgucgacaaa uuagaagaau     2160

uaaugaaaau aggaacacca gugaaaguaa gauuccaaga agcagaagaa agaccaaaaa     2220

uguuugaaga auuaggucag cgcuuacaac auuacgccaa aauugcagca gauuuuagaa     2280

auaaagauga aaaauauaac cauauugacg aaucagagau gaagaaagua gaaaaaucag     2340

ucaaugaagu aauggaaugg augaauaaug uaaugaacgc ucaagcaaag aaaucauuag     2400

accaagaccc aguagugaga gcccaagaaa uaaaaacaaa aauaaaagaa uuaaauaaua     2460

caugugaacc uguuguuaca caaccaaaac caaaaauaga aaguccaaaa cuagaacgaa     2520

cgccaaacgg accaaauaua gacaagaaag aagaagaucu agaagacaaa aauaacuucg     2580

gugcagaacc uccacaucaa aacggagaau guuacccaaa cgagaaaaac aguguaaaca     2640

uggacuuaga cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  7301
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt12)

<400>  7301
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccgauaaag uaaggcgcca acguccaaga agaagaguau      120

guugggcacu uguugcaguu cuacuugcag acuuauuagc acuaagugau acacuugcag      180

ugaugagugu agaucuugga uccgaaagca ugaaaguagc aaucguaaaa cccggaguac      240

caauggaaau uguacucaac aaagaaaguc gaagaaaaac accaguaauc guaacucuaa      300

aagaaaauga aagauuuuuc ggggauucug cagcaucuau ggcaauuaaa aacccaaaag      360

cuacauuacg uuacuuccaa cauuuacuug guaagcaagc agauaacccu cacguugcuc      420

uauaucaggc ucguuuccca gaacaugaac ucacauucga cccacaacga cagacaguac      480

acuuucaaau aucaagccaa uuacaauucu caccagaaga aguacuaggu augguacuaa      540

acuauucgcg aaguuuagca gaagacuucg cugaacaacc aauaaaagau gccguaauaa      600

cagucccagu cuucuuuaac caagcagaaa ggagagccgu ucuacaagcg gcuagaaugg      660

caggauuaaa aguauugcaa cuaauaaaug acaauacugc gaccgcccua aguuacggcg      720

uuuuucgaag aaaagauaua aauacaacag cccaaaacau aauguucuac gacaugggaa      780

guggaucaac aguaugcacu auaguuacau accaaauggu aaaaacgaag gaagcaggaa      840

ugcaaccaca gcuacaaaua agaggaguag gauuugaucg uacacuagga ggauuagaaa      900

uggaacuaag acuuagagaa cgcuuagcag gauuguucaa ugaacaaaga aagggccaac      960

gcgccaagga ugugagagag aauccaagag caauggcaaa auuacucaga gaggccaacc     1020

gguuaaaaac aguguuauca gcaaacgcag aucauauggc ucagauagaa ggacugaugg     1080

augacguuga uuucaaagca aaagucacac gaguugaauu ugaagaguua ugugcagauu     1140

uauucgaaag aguuccugga ccuguucaac aagcgcuaca aagugcagaa augaguuuag     1200

augagauuga acaagugauu cuaguuggcg gagcaacucg aguuccaaga guccaagaag     1260

uacuguuaaa agccguaggc aaagaagaau uagguaaaaa uauaaaugcc gaugaagcag     1320

ccgcaauggg agccguuuau caagcugcug ccuuaucgaa agcauuuaaa guaaaaccau     1380

uuguuguaag ggacgccgug guauacccaa uauuagucga guuuacacga gaagucgaag     1440

aagaacccgg aauacauuca uuaaaacaua acaaacgagu ucuauuuuca agaauggggc     1500

cguauccaca aagaaaagua auaaccuuua auagauacuc ccacgauuuu aauuuccaca     1560

uuaauuaugg agaucuagga uuuuuagguc cggaagaucu ucguguauuu gggucacaaa     1620

auuugacaac agucaaacua aaaggagucg gagacucauu uaagaaauau ccagauuaug     1680

aaucaaaagg aauuaaagcu cauuucaauu uggaugaaag uggaguacuc agucuagaua     1740

ggguagaaag cguauuugaa acauuagucg aagacucagc agaagaagaa agcacucuga     1800

cuaaacuagg aaauacaaua ucaucacuau ucggaggugg gacgacccca gaugcaaaag     1860

aaaauggaac agauacugua caggaagaag aagaaucacc agcagaagga agcaaggaug     1920

aaccagguga gcaaguagaa cuaaaagaag aagcagaagc accaguagaa gacggaaguc     1980

aaccaccucc accagaaccu aaaggagacg cgaccccaga aggagaaaaa gcuacagaaa     2040

aggaaaaugg agauaaauca gaagcucaaa aaccgucaga aaaagcugaa gcaggaccag     2100

aaggcguugc cccagcaccg gagggagaaa agaaacaaaa accagcaaga aaaagaagaa     2160

ugguggaaga aaucggugua gagcuaguag uauuagacuu accugacuua ccagaagaua     2220

aauuggcuca auccguucaa aaacuucaag aucuaacacu uagagacuua gaaaaacaag     2280

aacgagaaaa agcagcaaac ucacuagaag cauuuauauu cgaaacacag gauaaacuau     2340

accaaccaga auaccaagag guuucaacug aggaacaaag ggaagagauc ucaggaaaac     2400

ucagugcagc caguacaugg uuggaagacg aaggaguagg cgcaacaacg gucauguuaa     2460

aagaaaaacu agcggaacuu agaaaauuau gccaaggauu auuuuucaga guugaagaaa     2520

gaaagaaaug gccagaaaga uuauccgcuu uggauaauuu auuaaaucau ucaucaaugu     2580

uucuaaaagg cgcaagauua auaccugaaa uggaucaaau auucacagaa guagaaauga     2640

cuacauuaga aaaaguaaua aaugaaacuu gggcuuggaa aaaugcuaca cuagcagaac     2700

aagcaaaauu accagcuacc gaaaaaccag uacuacuauc aaaagacaua gaggcaaaaa     2760

ugauggcccu agacagagaa guucaauauc uacuaaauaa agcaaaauuu acuaaaccua     2820

gaccaagacc uaaagauaaa aaugguacac gagcugagcc uccacucaau gcguccgcau     2880

ccgaucaagg agaaaaaguu auacccccug ccggacaaac agaagacgca gagccaaucu     2940

cagaaccaga aaaaguggaa acaggaagug aaccuggaga cacagaacca cuagaacucg     3000

gagguccggg ggcagaacca gaacaaaaag aacagaguac aggacaaaaa cgaccgcuaa     3060

agaaugauga guuauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  7302
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt12)

<400>  7302
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaggaaa cccaaacuca agaucaacca auggaagaag      120

aagaaguaga aacauuugcu uuccaagccg aaauagcaca acugauguca cuaauaauaa      180

auacauuuua uucaaacaag gaaauuuucu ugagagaacu cauaaguaac ucaagcgacg      240

cacucgacaa aauaagauac gaaagccuaa cagacccguc uaaacuggac ucaggaaaag      300

agcuacauau aaaccuaaua ccuaacaaac aagauagaac acuaaccaua guagauacag      360

gaauagguau gacaaaagca gauuuaauaa acaaccuagg cacaauagcc aaguccggaa      420

ccaaagcguu cauggaagcg cuccaagccg gcgcagauau cagcaugaua ggacaauucg      480

ggguaggauu cuacucagca uaucuaguag cagaaaaagu aacgguuauc accaaacaua      540

augacgacga acaguacgca ugggaaaguu cggcaggcgg cucauucaca gucagaaccg      600

acaccgggga accaauggga agagguacaa agguaauacu acaccuuaaa gaagaccaaa      660

cagaauaccu agaagaaagg agaauaaaag aaauaguaaa aaaacacuca caauucauug      720

gauacccaau aacauuauuu guagaaaaag aaagagacaa agaaguaagc gacgaugaag      780

cagaagaaaa agaagauaaa gaagaagaga aagaaaaaga agagaaagaa agugaagaca      840

aaccagaaau agaagacguu ggcucggaug aagaagaaga aaaaaaagac ggagauaaaa      900

aaaaaaaaaa aaaaauaaaa gaaaaguaca uagaucaaga agaacucaau aaaacaaagc      960

caauauggac acgaaaucca gaugacauaa cuaacgaaga auacggcgaa uuuuauaaaa     1020

guuuaacaaa cgacugggaa gaccaucucg caguaaaaca uuuuucagua gaaggacaac     1080

uagaauucag agcacuauua uucgucccca gaagagcacc auuugauuua uuugaaaaua     1140

gaaaaaaaaa aaacaacauu aaacuauaug uaagaagagu uuucauaaug gacaauugug     1200

aagaauuaau accagaauau cuaaacuuua uaagaggggu gguugacagc gaagauuuac     1260

cgcuuaacau aagccgagaa auguugcaac agaguaaaau acuaaaagua auaagaaaaa     1320

aucuaguaaa aaaauguuua gaauuauuua cggaauuagc agaggacaaa gaaaacuaca     1380

agaaauuuua cgaacaauuc aguaaaaaca uaaaauuagg cauacacgaa gacagucaaa     1440

auagaaagaa acuaucagaa cuacuaagau auuacacaag ugcaagugga gaugaaaugg     1500

uaagcuuaaa agacuacugu acaagaauga aggaaaacca aaaacauaua uauuauauaa     1560

caggagaaac aaaagaucaa guagcaaaca gugccuucgu agaaagacua agaaaacaug     1620

ggcuagaagu aauauacaug auagaaccua uagaugaaua uugcguacaa caacuaaaag     1680

aauuugaagg aaaaacccua guaucgguaa caaaggaagg auuagaauua cccgaagaug     1740

aagaagaaaa aaagaaacaa gaagaaaaaa aaacaaaauu cgaaaaccua ugcaaaauaa     1800

ugaaagauau acuagaaaaa aaaguugaaa aaguuguggu aucuaacaga uuaguaacuu     1860

caccaugcug caucguaacu aguacguaug gcuggacagc aaacauggaa agaauaauga     1920

aagcacaggc uuugagagau aacaguacca ugggauauau ggcagcaaaa aaacaucuag     1980

aaauuaaucc agaccacagu auaauagaaa cguuaagaca gaaagcagaa gcggacaaga     2040

acgacaaauc aguaaaagac cucguuauac uacucuauga aacagcacua cuaagcagug     2100

gauuuucauu agaagaucca cagacacacg caaacaggau uuauagaaug auuaaacuug     2160

gacucggaau agacgaagau gacccaacag cagaugacac aagugcagca gugaccgaag     2220

aaaugccacc guuagaaggg gaugacgaca cuaguagaau ggaagaagua gauuaaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  7303
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt12)

<400>  7303
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucaa aacuagacuc aggaaaagga cuacacauaa      120

accuaguacc aaacaaacaa aaccaaacac uaacaauagu agacacaaga auaggaauga      180

caaaaacaga ccuaauaaac aaccuaggaa caguaacaaa aagcggaaca aaagcauuua      240

uggaagcacu acaagcagac gcagacauaa gcaugauagg acacuucgga guaggauucu      300

acucagcaua ccuaguagca aaaaaaguaa caguaauauc aaaacacaac aacgacgaac      360

aauacacaug ggaaucaagc gcaggaggaa gcuucacagu aagaacagac gaauaaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  7304
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt12)

<400>  7304
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaagaag uacaccaugg agaagaagag guagaaacau      120

ucgcauuuca agcagagauu gcacaacuaa ugaguuugau aauaaauaca uuuuauagca      180

acaaagaaau auuuuuaaga gaacuaauuu cuaacgcaag cgacgcauua gacaaaauac      240

gauaugagag ucuaacugau ccaaguaaac uagauagugg aaaggaacuu aaaauagaca      300

uaauaccgaa uccacaagaa cgaacauuga cacuagugga cacaggcaua ggaaugacaa      360

aggccgaucu aauaaauaau cuuggcacaa uagcaaaaag ugggacuaaa gcguuuaugg      420

aggcacuaca agcgggagca gauauaagua ugauaggaca auuuggaguu ggauuuuauu      480

cagcauacuu aguggcagaa aaaguugucg uaauaacaaa acauaacgau gacgaacaau      540

acgccuggga aucaagcgca ggaggaaguu uuacaguaag agcagaccac ggugaaccaa      600

ucggaagggg aacaaaagua auacuacacu uaaaagaaga ucaaacagag uauuuggaag      660

aacgaagggu aaaagaagua guaaaaaaac acucacaauu uauaggauau ccgauaacau      720

uguaccuaga aaaggaaagg gaaaaagaaa uaagcgauga cgaagcagaa gaagaaaaag      780

gggaaaagga agaagaagau aaagacgaug aagaaaaacc aaaaauagag gacguaggaa      840

gugaugaaga agaugacuca ggaaaagaua aaaaaaaaaa aacuaaaaaa aucaaagaaa      900

aauacauaga ucaagaagaa uuaaauaaaa caaagccaau auggaccaga aacccagacg      960

acauaacaca agaagaauau ggcgaauucu auaaaagucu aacaaaugac ugggaagacc     1020

accuagcagu aaaacacuuc agcgucgaag gucaauuaga auucagagcu cuacuauuua     1080

uaccaagaag agcaccauuc gaucuauucg aaaacaaaaa aaaaaaaaau aauauaaaac     1140

ucuacguccg cagagucuuu auaauggacu cgugcgacga acuaauccca gaauauuuaa     1200

acuuuaucag agggguagua gacucagagg accucccacu aaacauaagc agggaaaugc     1260

uucaacaaag caaaauccua aagguaauca gaaaaaauau cgucaaaaaa ugccucgaac     1320

uauuuucaga auuagccgaa gauaaagaaa acuacaaaaa auuuuacgaa gcauucagca     1380

aaaauuuaaa acuaggcaua cacgaagacu ccacaaacag aagaagauua agcgaauuac     1440

uaagauauca cacaucacag ucgggagaug aaaugacauc uuuaucagag uacguaagcc     1500

gaaugaaaga aacacaaaaa aguauauacu auaucacugg agaaaguaaa gaacaaguag     1560

cgaacucagc auuuguagaa cguguaagaa aacgaggauu ugaaguagua uacaugacag     1620

aaccaauuga cgaauacugu guccaacaau uaaaagaauu cgaugguaaa aguuuaguuu     1680

caguaacaaa agaaggauua gaauuaccug aagacgaaga agaaaagaaa aaaauggaag     1740

aaagcaaagc aaaauuugaa aaucuaugca aacucaugaa agaaauauua gacaaaaaag     1800

uggaaaaagu cacgauuucc aacagacucg uaagcucacc cuguugcaua guaacaucua     1860

cauaugguug gacugcaaac auggaaagaa uaaugaaagc acaagcuuug agagacaauu     1920

caacaauggg auauaugaug gcaaagaaac auuuagaaau aaacccagac cauccaaucg     1980

uagaaacacu gagacaaaag gcagaagcag acaaaaauga uaaggccgug aaagaucuug     2040

ugguacuucu auucgaaaca gcccuacuga guaguggauu caguuuagaa gacccacaaa     2100

cacacuccaa uagaaucuau cgaaugauca aacuaggauu aggaauagac gaggaugaag     2160

uagcugcaga agaaccaaau gcagcaguac cagaugaaau accaccgcua gaaggagaug     2220

aagaugcgag ccgcauggaa gaaguagacu agggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  7305
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt12)

<400>  7305
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agagcacugu ggguauuagg auuaugcugc guauuacuaa      120

cguuuggauc agugagagca gaugaugaag ucgauguuga uggaacagua gaggaagacc      180

ucgguaaaag uagagaaggc ucaagaacug acgacgaagu uguucaaaga gaagaagaag      240

cgauacaauu agauggauua aaugcaucac aaauaagaga acuucgugaa aaaucagaaa      300

aauuugcguu ucaagcagaa guaaacagaa ugaugaaacu aauaauaaau ucauuauaca      360

aaaauaaaga aauauuuuua agagaacuua uuucaaacgc aagcgaugca uuggauaaaa      420

uaagauugau aagucuaaca gaugaaaacg ccuuaucagg aaaugaagaa uuaacaguaa      480

aaauaaaaug cgauaaagag aaaaauuuac uacauguaac ugacacggga guaggaauga      540

caagagaaga auuagucaaa aauuugggaa caauagccaa aucaggaacc ucagaauuuc      600

uaaacaaaau gacugaagca caagaagacg ggcaaucaac aagugaauua auaggacaau      660

uugggguagg auucuacagu gcguuuuuag uagcggacaa gguaauagua accaguaaac      720

auaauaacga cacacaacau auaugggagu cagacaguaa cgaguucagu guaaucgcag      780

acccgagagg uaacacauug ggacgaggaa caacuauaac guuaguacuc aaagaagagg      840

cuucagauua ccuagaacug gauacaauaa agaaucucgu gaagaaauau ucccaauuca      900

ucaacuuccc aauauacgua uggaguucaa aaacagaaac aguggaggaa ccaauggaag      960

aagaagaagc agcuaaagaa gagaaagaag aaucagauga ugaagcugca gucgaagaag     1020

aagaagaaga aaagaaaccg aaaacuaaga aaguagagaa aacaguuugg gauugggaac     1080

uaaugaacga cauaaaacca auuuggcaac gaccgucaaa agaaguggaa gaggaugaau     1140

auaaagcauu uuacaaauca uucucuaaag aaucagauga uccaauggca uauauacauu     1200

uuacagcaga aggggaagua acauuuaagu caauccuauu uguaccaacc ucagcaccga     1260

ggggauuauu cgacgaauau ggaagcaaga aaucggauua uauaaaacua uauguaagaa     1320

ggguauuuau aaccgaugau uuccacgaua ugaugcccaa auaucuaaau uuuguaaaag     1380

gaguaguaga cagcgacgau cuaccauuaa auguaucucg agaaacacuc caacagcaua     1440

aacuccuaaa aguuauaagg aagaaauuag ucaggaaaac acucgauaug auaaagaaaa     1500

uagcagauga uaaauauaac gacacauuuu ggaaagaauu ugguacaaau auuaaauuag     1560

gaguaaucga agaucacagu aacagaacga gauuagcaaa acuauugaga uuucaaaguu     1620

cacaccaccc aacagauaua acuagcuuag accaauaugu ggaaaggaug aaagaaaaac     1680

aagauaaaau uuauuuuaug gcagggagua guaggaaaga agcugaaagu agccccuucg     1740

uggaaagauu auuaaagaaa ggauaugaag uaauauaucu aacagaacca guagacgaau     1800

auuguauaca agcacuacca gaguucgacg gaaaaagauu ucaaaaugua gccaaagaag     1860

gaguaaaauu ugacgaguca gagaaaacaa aagaaagcag agaagcagua gaaaaagaau     1920

uugaaccucu acuuaacugg augaaagaua aggcuuuaaa agauaaaaua gaaaaagcag     1980

uaguaagcca aagacuuaca gaaucaccau gugcauuggu agcaagucaa uauggaugga     2040

guggaaacau ggaaaggaua augaaagcac aagcguacca aacaggaaaa gauauaucaa     2100

cgaauuacua ugccagccag aaaaagacau ucgaaauaaa uccaagacac ccauuaauaa     2160

gagacauguu aagaagaauu aaagaagaug aagaugauaa aacuguauua gaccuugcag     2220

uaguuuuguu cgaaacggca acauuacgaa guggcuaucu gcuaccggau acaaaagcau     2280

auggagacag aauagaacga auguuaagac uaucauuaaa uauagauccu gaugccaaag     2340

uagaagaaga accagaagaa gaaccagaag aaacggcaga agauacaaca gaagacaccg     2400

aacaagacga ggaugaggaa auggacguag gaacugauga agaagaagaa acagcaaaag     2460

aaagcacugc agaaaaagau gaacuauaag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  7306
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt12)

<400>  7306
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaagagaac uaagagcauu acuauuaugg ggccgccgac      120

uaagaccucu cuuaagagcu ccagcacuag cagccguacc aggcggaaag cccauacuau      180

guccaaggag aacaacugca caacuaggac caagaagaaa uccugcuugg agucugcaag      240

cagguaggcu uuucuccaca caaacagcug aagacaaaga agaacccuua cauucaauaa      300

uaucuaguac agaaucuguu caaggaagua ccucaaaaca ugaauuucaa gcagaaacaa      360

aaaaacuacu agacauagua gcacgaucac uauauaguga aaaagaaguu uuuauaagag      420

aauuaauaag uaacgccuca gaugcacuag aaaaauuacg acacaaauua guaagcgaug      480

gucaagcuuu accagaaaug gaaauacauu uacaaacuaa cgcugaaaaa ggaaccauua      540

caauacaaga uacagguaua ggaaugacac aagaagaacu uguuaguaau cuaggaacaa      600

uagcucgauc aggaucaaaa gcauucuuag acgcauuaca aaaccaagca gaagcuagcu      660

cgaaaauaau uggucaauuu ggaguaggau uuuauucagc auucaugguu gcagacaggg      720

uagaaguaua uucacguagc gcugcaccag gaucauuagg uuaccaaugg cuaucagacg      780

guucaggcgu uuucgaaauc gcagaagcau caggaguaag aacaggaaca aaaauaauaa      840

uacaccuaaa aagugauugu aaagaguucu cuagugaagc aagaguuaga gauguaguaa      900

caaaauauuc uaauuuugua ucguuuccac uauacuuaaa uggacgaaga augaauacac      960

uacaagcaau auggaugaug gauccaaaag auguacgaga auggcaacau gaagaauucu     1020

acagauacgu ugcacaagca caugacaaac caagauauac cuuacauuau aaaaccgacg     1080

caccuuuaaa uauaagauca aucuuuuaug uuccagacau gaaacccucu auguucgacg     1140

uaucaagaga acuaggaagu aguguggccc uuuauucaag aaaaguccua auucaaacaa     1200

aagcaacaga uauauuaccu aaaugguuga gauuuaucag aggaguagua gauucagaag     1260

acaucccauu aaaucuaagu agggagcuau uacaagaauc agcauuaaua aggaaacuaa     1320

gagacguuuu acaacaaaga cuuauaaaau uuuuuauaga ucaaagcaaa aaagaugcag     1380

aaaaauacgc uaaauuuuuc gaagacuaug ggcuauuuau gagagaggga auaguaacag     1440

caacugaaca agaaguaaaa gaagacauug caaaacuacu cagauaugaa aguagugcuc     1500

ugccuagcgg ucaauuaaca agucugucug aauaugcuuc acgaaugagg gccggaacaa     1560

gaaauauaua cuacuuaugc gcaccaaacc gacacuuagc agaacauuca cccuauuaug     1620

aggcaaugaa aaagaaagac acagaaguuc uauuuugcuu ugaacaauuc gacgaacuca     1680

cuuuacuaca ccuaagagaa uuugacaaaa aaaaauuaau uagcgucgaa acagauauag     1740

ugguugacca uuauaaagaa gaaaaauuug aggauagauc uccagcggcc gaaugccuuu     1800

cagaaaaaga aacagaagaa cuuauggccu ggaugagaaa cguucuaggg ucuagaguaa     1860

caaaugugaa aguaacauua agauuagaca cacauccggc aaugguaaca guucuagaaa     1920

ugggagcggc aagacacuuu uuaagaaugc aacaauuggc aaaaacacag gaagaaagag     1980

cacaauuauu acagccaaca cucgaaauca acccuagaca cgcauuaaua aaaaaacuaa     2040

aucaacuaag agcaucagaa ccaggacuug cacaauugcu agucgaucaa auauacgaaa     2100

augcaaugau agcagcagga uuaguagaug auccacgagc gaugguagga cgacuaaaug     2160

aguuauuagu aaaagcauua gaaagacacu aaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  7307
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt12)

<400>  7307
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaauau caucacuacc aacacaacua uucaaaugcu      120

gcuucugcga cuuccuaaaa guaaaaaugc acacaauguc aucaucacac cuauucuacc      180

uagcacuaug cuuauuaaca uucacaucau cagcaacagc aggaccagaa acacuaugcg      240

gagcagaacu aguagacgca cuacaauucg uaugcggaga cagaggauuc uacuucaaca      300

aaccaacagg auacggauca ucaucaagaa gagcaccaca aacaggaaua guagacgaau      360

gcugcuucag aucaugcgac cuaagaagau uagaaaugua cugcgcacca cuaaaaccag      420

caaaaucagc aagaucagua agagcacaaa gacacacaga caugccaaaa acacaaaaag      480

aaguacaccu aaaaaacgca ucacgaggau cagcaggaaa caaaaacuac agaauguaag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  7308
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt12)

<400>  7308
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaauaccaa ugggaaaauc aaugcuagua cuacuaacau      120

uucuagcauu cgcaucaugc uguauagcag cauacagacc aucagaaaca cuaugcggag      180

gagaauuagu agauaccuua caauuuguau guggagacag aggauucuau uucucaagac      240

cagcaucaag aguaucaaga agaucaagag gaauaguaga agaaugcugu uucagaucau      300

gugacuuagc auuacuagaa acauauugcg caacaccagc aaaaucagaa cgagauguau      360

caacaccacc aacaguacua ccagauaacu uuccaagaua cccaguagga aaauuuuucc      420

aauacgauac auggaaacaa ucaacacaaa gacuaagaag aggacuacca gcacuacuaa      480

gagcaagaag aggacacgua cuagcaaaag aacuagaagc auuuagagaa gcaaaaagac      540

auagaccacu aauugcauua ccaacacaag auccagcaca cggaggagca ccaccagaaa      600

uggcaucaaa cagaaaauaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  7309
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt12)

<400>  7309
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacucauucu caacaucagc auucggacca guagcauucu      120

cacuaggacu acuacuagua cuaccagccg cauucccagc accaguacca ccaggagaag      180

acucaaaaga cguugcagca ccacacagac aaccccuaac auccucagaa agaauagaca      240

aacaaauaag auacauacua gacggaauau cagcacuaag aaaagaaaca ugcaacaaau      300

caaacaugug cgaaucauca aaagaagcac uagccgaaaa caaccuaaac cuaccaaaaa      360

uggcagaaaa agacggaugc uuccaaucag guuucaacga agaaacaugc cuaguaaaaa      420

uaauaacagg acuccuagaa uucgaaguau accuagaaua ccuacaaaac agauucgaau      480

caucagaaga acaagcaaga gcaguacaaa ugucaacuaa aguacuaaua caauuccuac      540

aaaaaaaagc aaaaaaccua gacgcaauaa caacaccaga cccaacaacc aacgcaucac      600

uacucacaaa acuacaagca caaaaccaau ggcuacaaga caugacaaca caccuuauac      660

uacgaucauu caaagaauuc cuccaaucau cccuccgagc ccucagacaa auguaaggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  7310
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt12)

<400>  7310
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccauuacuau gguuaagagg auuuuuauua gcuaguugcu      120

ggauaauagu cagaucaagc ccaacgccag gaagcgaagg acacucagca gcuccagacu      180

guccaaguug ugcauuagca gcauuaccua aagauguucc uaauucacaa ccagaaaugg      240

uagaagcagu aaaaaaacau auauuaaaua uguuacacuu aaaaaaaagg ccagacguaa      300

cacaaccagu uccaaaagca gcauuauuga acgcaauaag aaaauuacac guaggaaagg      360

uaggggaaaa cggauaugua gaaauagaag acgauauagg aagaagagca gaaaugaaug      420

aacuaaugga acaaacaagu gaaauaauaa cuuucgcaga aagcggaaca gcaagaaaaa      480

cacuacacuu ugaaauaagu aaagaaggga gcgauuuauc aguaguagaa agagcagaag      540

uaugguuauu ucuaaaagua ccaaaagcaa auagaacuag aacaaaagua acaauaagac      600

uauuccaaca acaaaaacau ccacaaggau cuuuagauac uggagaagaa gcggaagaag      660

uaggacuuaa aggagaaaga ucagaacuac uauuaaguga aaaaguagua gaugcacgaa      720

aaaguacaug gcauguauuu ccaguaucca guucaauaca aagacuauua gaucaaggaa      780

aaagcagcuu agacguuaga auagcuugug aacaguguca agaaucagga gcaaguuuag      840

uuuuacuagg aaaaaaaaaa aaaaaagaag aagagggaga agguaaaaaa aaaggugggg      900

gagaaggagg agcaggagcu gaugaagaaa aagaacaauc acauagaccc uucuuaaugc      960

uacaagcaag acaaucagaa gaucauccac auagaagaag acgaagaggc uuagaaugug     1020

auggaaaagu aaauauaugu ugcaaaaaac aauucuuugu aucauuuaaa gauauaggau     1080

ggaaugauug gauaauugca cccagcgguu aucaugcaaa cuauugugaa ggagaaugcc     1140

caucacacau agcgggaacu aguggaaguu cauuaagcuu ucacucaacu gugauaaauc     1200

auuaucguau gagaggccau ucgccguuug caaauuuaaa aucauguugu guaccaacaa     1260

aacuaagacc aaugaguaug uuauauuaug acgauggaca aaauauaaua aagaaagaca     1320

uacaaaauau gauaguagaa gaauguggau guaguuaagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  7311
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt12)

<400>  7311
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacggauuac cuggcagagc uuugggagca gcaugucuau      120

uacuauuagc ugcaggaugg uuaggaccag aagcaugggg aucgccaaca ccaccaccaa      180

caccagcugc accaccacca ccaccaccuc cugguucacc aggcgggucu caagacaccu      240

guacaagcug uggaggcuuu aggaggccag aagaacuagg aagaguagau ggagacuuuu      300

uagaagcugu aaaaagacau auacuuagua gacuccaaau gagaggaaga ccaaauauaa      360

cacaugccgu accaaaagcu gcaaugguaa cugcacuucg aaaacuacau gcaggaaaag      420

uaagagaaga uggaagggua gaaauaccuc aucuagaugg acaugcauca ccaggagcag      480

auggacaaga aagaguauca gaaauaauau cuuuugcaga aacagaugga uuagcgucau      540

caagaguaag auuauacuuu uucauaucaa acgaaggaaa ucaaaauuua uuuguaguac      600

aagcgagcuu augguuauau cuaaaauuau uacccuaugu uuuagaaaaa ggaucaagac      660

gaaaaguaag aguaaaaguu uauuuucagg aacaaggaca cggagacaga uggaauaugg      720

uagaaaagag aguagacuua aaaagaagug gauggcauac auucccacua acugaagcaa      780

uucaagcacu auuugaaaga ggagaaagaa gauuaaaccu agaugugcaa ugugauucuu      840

gucaagaauu agcagucgua ccaguauuug uugauccagg agaagaaagu cauagaccau      900

uugugguagu ucaagcaaga uuaggagaua guagacauag gauaagaaaa agaggauuag      960

aaugugaugg aaggacaaau uuauguugua gacaacaauu cuuuauugac uuuagauuaa     1020

uaggauggaa ugauuggaua auagcaccca caggauauua ugggaauuau ugugaaggaa     1080

guuguccagc auacuuagca ggaguacccg gaucagcaag uuccuuucau acagcaguug     1140

ucaaccaaua ucgaaugaga ggguuaaauc cagguacagu aaacucaugu uguauaccaa     1200

ccaaacuaag uacuaugagc auguuauauu uugaugauga auauaacauu guaaaacgag     1260

auguaccaaa caugauagua gaagaaugug gaugugcaua aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  7312
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt12)

<400>  7312
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcauuaagag uauuacugcu gacagcuuug acucuauguc      120

acggcuucaa ccuagacaca gaaaaugcua ugaccuuuca agaaaaugca cgagguuucg      180

gacagucugu cguccaacua caaggaucaa ggguuguagu cggcgcaccc caagaaauug      240

uagcagcaaa ucaaagaggc uccuuauauc aaugcgacua cucaacaggu agcugcgaac      300

caauacgucu ucaaguuccc guugaagcag ugaacauguc acuugguuua aguuuagcag      360

cuacaacaag cccaccucaa cuauuagcuu gcggccccac aguacaccaa accuguagcg      420

aaaauacuua uguuaaagga uuguguuucc uauucgguuc caauuuacga cagcaaccuc      480

aaaaauuccc ugaagcacuu cguggaugcc cccaagaaga uagcgauaua gcauuuuuaa      540

ucgacgguuc cggauccaua auaccccaug acuuccggag aaugaaagaa uuuguaagua      600

cagugaugga acaauugaag aaaucuaaaa cucuauuuuc ucugaugcaa uauagugaag      660

aauuuaggau acacuuuacu uuuaaagaau uucaaaacaa cccaaauccg agaucguuag      720

uaaaaccgau uacucagcuu uuaggacgaa cucauacagc uacuggaaua cguaaaguag      780

uaagagaacu cuucaacaua acaaauggcg cacguaaaaa ugcuuuuaag auauuaguag      840

uaauuacaga cggagaaaaa uucggagauc cucuaggaua cgaagacgua auaccagaag      900

cugauagaga gggcguaaua agauauguaa uaggcguugg agaugcauuc agaagcgaga      960

aaagcagaca agaauugaac acaaucgcau cuaaaccccc acgagaucau guauuccagg     1020

ucaauaauuu cgaagcucua aaaacaauac aaaaccaacu gagagagaaa auauuugcaa     1080

uagaagggac acaaacaggc ucaucgagcu cauuugaaca ugaaaugagc caagaaggau     1140

uuucagcagc aauaaccuca aacggaccac uauuauccac uguuggaagu uaugauuggg     1200

cagggggagu cuucuuauac acguccaaag aaaaaucuac auuuauaaac augaccagag     1260

uugacaguga caugaaugac gcuuaccucg gcuaugcagc agcuauuaua cuacgaaaua     1320

gaguacaauc acuuguuuua ggggcaccac gguaccaaca uauuggucua guugccaugu     1380

uccgacaaaa uacaggaaug ugggaaucaa augccaaugu aaaaggaaca caaauaggag     1440

cuuauuucgg cgcaucauua uguuccguag auguagacuc aaacggauca acagauuuag     1500

uccugauugg ugccccacau uauuaugaac aaacaagagg uggucaggua aguguuuguc     1560

cgcucccacg agguagagcc cgauggcaau gcgaugcugu acuuuaugga gaacaaggac     1620

agccaugggg aagauucggg gcagcacuaa caguacuagg ugacgugaau ggggauaaac     1680

uaaccgaugu agcaauaggu gcaccaggcg aagaagacaa uagaggagca guauacuuau     1740

uucacggaac aucaggcuca ggaauaagcc cuucgcacuc acaaagaauc gcuggcagua     1800

aauuaagccc ucgccuucaa uacuuuggac agucgcuuag uggaggccaa gaucuaacaa     1860

uggacggauu aguugaccua acgguaggag cacaggguca uguccuacua uuacgauccc     1920

aaccuguuuu gcgugucaaa gcaauuaugg aguucaaucc aagagaagua gcacgaaaug     1980

uuuuugaaug caaugaucaa guaguuaaag gcaaagaagc uggagaagua cggguuuguc     2040

uacauguaca aaaauccaca cgagaccguc uacgcgaagg ucaaauacaa ucaguaguua     2100

ccuaugaucu ugcacuugac ucuggaagac cucacucuag ggcuguauuu aaugaaacua     2160

aaaauuccac gagacgacaa acacaaguac uaggucuuac ccaaacuugu gaaaccuuaa     2220

agcuacaacu cccaaauugc auagaagauc caguaagucc aauaguacug agacucaauu     2280

ucucccuugu cggaaccccu cuaagcgcgu ucggaaacuu acgaccagua cuagcagaag     2340

acgcacagag acuuuuuacu gcacuuuuuc cauucgagaa aaauugcgga aacgacaaua     2400

uaugucaaga cgacuuaucu auaacauuuu cauucauguc auuagauugu uugguaguug     2460

gagguccccg ggaguucaau gucacaguaa cagucagaaa ugauggagaa gauucuuacc     2520

gaacacaagu uaccuuuuuc uuuccacuug auuuaagcua ccgaaaaguc ucuacacuac     2580

agaaccaacg aagucaacgc ucguggagac uugcauguga aagcgcuucu ucaacugaag     2640

uuucaggugc uuugaaauca acaucaugua guauaaacca ucccauuuuu ccggaaaauu     2700

cugaaguuac auuuaacauu acguucgaug ucgauucaaa ggcuucucuu gguaauaaau     2760

uacuauugaa agcaaauguc acauccgaaa auaauaugcc aaggaccaac aaaacagagu     2820

uccaacuuga auuaccugua aaauaugcug ucuacauggu uguaacauca cauggaguau     2880

cuaccaaaua ucucaauuuu acagcaucug aaaauacuuc acgaguaaug caacaccaau     2940

accaaguauc aaauuuagga caacgaucac ucccaauuag ucuuguuuuu cuagucccag     3000

ucagauugaa ucaaacagua aucugggaua gaccacaagu aacauuuucu gaaaacuuaa     3060

gcaguacaug ucauacaaaa gaacgcuuac caucccauuc cgacuuucuu gcugaauuaa     3120

gaaaagcacc ugucgucaau ugcucaaucg cagugugcca acgaauacaa ugugacauuc     3180

ccuucuuugg cauacaagaa gaguuuaacg cuacacuaaa gggcaauuua uccuuugacu     3240

gguacauaaa aacaucacau aaucaucuau uaauuguauc aacagcagaa auauuauuua     3300

acgacagcgu auucacacuu cuccccgggc aaggagcuuu ugucagaagu caaacagaaa     3360

caaaaguaga accauucgaa guuccaaacc ccuuaccucu cauaguaggu uccucgguag     3420

guggauuacu acugcuugca uuaauuacag ccgcuuuaua uaaacuugga uucuuuaaga     3480

gacaauauaa ggauaugaug ucugaaggag gaccuccugg cgcagaacca caauaaggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  7313
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt12)

<400>  7313
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucacuua aaacucuccc auucuuacua cuacuacacg      120

uccaaauauc aaaagccuuc cccguauccu caaaagaaaa aaauacuaaa acaguucaag      180

acuaccucga aaaauucuac caacuaccuu caaaccaaua ccaaucaaca agaaaaaaug      240

guacuaaugu cauagucgaa aaauuaaaag aaaugcaaag auuuuuugga cuuaacguua      300

caggaaaacc uaacgaagaa acccuagaca ugaugaaaaa accacgaugc ggagucccag      360

acucaggagg cuucaugcua acaccaggaa auccaaaaug ggaacguaca aacuuaacau      420

accgcauacg aaacuacacc ccacaacuaa gugaagcaga aguagaacgc gccauaaaag      480

acgccuucga acuaugguca guagcaagcc cacucauauu uacuagaaua ucacaaggug      540

aagcugauau caauaucgca uuuuaccaac gagaccacgg cgauaacuca ccauucgacg      600

gcccaaaugg aauacuagcc cacgcauucc aaccaggaca aggaauagga ggugacgcac      660

acuucgacgc agaagaaacc uggacaaaca caucagcaaa cuauaacuua uuucuagucg      720

ccgcacacga auucggacac ucacuagguu uagcacacuc aucagaccca ggcgcacuaa      780

uguaucccaa cuaugcauuc agagaaaccu caaauuauuc auuaccucaa gacgauauag      840

acggaauuca agcaauauau ggacuuucuu caaauccaau acaaccaaca ggcccuucaa      900

ccccaaaacc cugugauccc ucacuaacau ucgacgcaau cacaacucua cgaggagaaa      960

uuuuauucuu uaaagacaga uauuuuugga gaagacaccc acaacuacaa agaguagaaa     1020

ugaacuucau aagcuuauuc uggccaucac uaccaacagg cauucaagca gcauacgaag     1080

acuucgauag agaccuaaua uucuuauuua aaggaaacca auauugggca cuaucagguu     1140

acgacauacu acaaggauac ccaaaagaca uauccaauua uggauuccca ucaucaguac     1200

aagcaauaga cgcagcagua uucuauagau caaaaaccua cuucuucgua aaugaucaau     1260

ucuggagaua cgacaaccaa cgccaauuca uggaacccgg auaucccaaa ucaauaucag     1320

gagcauuccc aggaauagaa ucaaaaguag acgcuguauu ccaacaagaa cauuucuuuc     1380

augucuucuc cggacccagg uacuacgcau uugauuuaau agcccaaaga guaacacgag     1440

uagcaagagg aaauaaaugg uugaauugua gauacggaua aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  7314
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt12)

<400>  7314
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agccuuuggc aacccuuagu uuuaguuuua cuaguauuag      120

gaugcugcuu cgcagcuccu agacaaaggc aaucaacacu uguucucuuu ccaggagacu      180

uacgaacaaa ucuaacagau agacaacuag cagaagaaua cuuauauaga uauggauaua      240

ccagaguugc agaaaugaga ggagaaagua aaucguuagg accugcccua cuacuucuuc      300

aaaaacaauu aucauuacca gaaacaggag aacuagauuc ugcuacacua aaagcaauga      360

gaaccccuag augcggaguu ccagauuuag gccgauuuca aacauuugaa ggagaccuaa      420

aauggcacca ucauaauaua acuuauugga uacaaaauua cucugaagac uuaccgagag      480

ccguaauaga cgaugcauuc gcuagagcau uugcuuuaug gucagcaguu acaccccuaa      540

cauuuacuag aguauauuca agagaugcug auauaguaau ucaauuugga gucgcagaac      600

auggugaugg auauccauuu gauggaaaag acggauuauu agcccacgca uucccaccug      660

guccaggcau ucaaggagau gcacauuucg acgaugacga auuauggagc uuaggaaaag      720

gaguaguagu accuacacgc uuugggaaug cugauggagc agcaugccau uucccauuua      780

uuuucgaagg uagaucauac ucugcaugca cuacagaugg aagauccgau ggauuaccuu      840

ggugcagcac aacagcuaau uaugacacug augacagauu ugguuuuugu ccauccgaaa      900

gacuuuacac acaagacgga aaugcagaug guaaaccaug ccaauuuccu uuuauauuuc      960

agggacaauc auauucagcu uguacaacag augggagaag ugauggauac cgcuggugug     1020

caaccacugc caauuaugau agagacaagc uauuuggauu cuguccuaca agagcagacu     1080

cgacuguaau ggguggaaau ucagccggag aacuaugugu cuucccauuu acauuuuuag     1140

guaaagaaua cucuacaugu acuucagaag gccgugguga uggaagacuu uggugugcaa     1200

caacaucaaa uuucgacucu gacaaaaaau ggggauuuug uccagaucaa ggauacagcu     1260

uauuucuagu ugcagcacac gaauuuggac augcacuagg uuuagaucac aguucaguac     1320

cagaagcauu aauguaucca auguauagau uuaccgaagg gccuccccuu cacaaagaug     1380

acguuaaugg aauaagacac uuauacggac ccagaccuga accugaacca agaccuccua     1440

cuacaacuac uccacaacca acagccccac caacaguaug cccaacggga ccgccaacag     1500

uacacccaag cgaaagacca acugcuggac caacaggacc acccagugca gguccaacug     1560

guccaccuac agcaggccca ucuacugcaa caacaguccc auuaagucca guggacgaug     1620

caugcaacgu uaacauauuc gacgcaauug cagaaauugg aaaucaauua uaucuuuuua     1680

aagauggaaa auacuggagg uucucagaag gaagagguuc aagaccacaa gguccauuuc     1740

uuauagcuga uaaauggcca gcucucccca gaaaauuaga cucaguauuc gaagaacgau     1800

uaaguaaaaa auuauucuuc uuuucaggca gacaaguuug gguauauacu ggugcaagug     1860

uacucggacc aagaagacuu gauaaauuag gcuuaggggc agacguugca caaguaacug     1920

gagcccuaag auccggucga ggaaaaaugu uauuauucuc aggaagaaga uuauggagau     1980

uugauguuaa agcacaaaug guugauccaa gaucagcauc agaaguagac agaauguuuc     2040

caggcguacc acuagauacu caugacguau uucaauaucg ggaaaaagcg uacuuuuguc     2100

aagauagauu uuauuggaga guuucuucaa gaucagaauu aaaccaagua gaucaaguug     2160

gauauguaac auaugauauc cuacaaugcc cagaagacua aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  7315
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt12)

<400>  7315
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacccaggag uacuagcagc auucuuauuc uuaucuugga      120

cccacuguag agcacuaccu cuaccuagcg gaggagauga agaugaccuc ucagaagaag      180

accuacaauu cgcagaaaga uaucuacgau cuuauuacca cccaacaaac uuagcaggaa      240

uacuaaaaga aaacgcugca ucaucaauga cagaaagacu aagagaaaug caaucauuuu      300

ucggacuaga aguaacagga aaauuagacg acaacacauu agacguaaug aaaaaaccaa      360

gaugcggagu accagauguc ggagaauaca acgucuuccc aagaacauua aaauggagca      420

aaaugaaccu aacauauaga auaguaaauu acacacccga caugacacac ucagaaguag      480

aaaaagcauu uaaaaaagca uucaaaguau gguccgaugu cacaccccua aacuucacaa      540

gauuacauga cggaauagca gacauaauga uaucuuucgg aauaaaagaa cacggugacu      600

ucuacccuuu cgacggacca ucaggacuau uagcacacgc auucccaccc ggaccaaauu      660

acggaggaga ugcacacuuu gacgaugaug aaacuuggac aucaucauca aaagguuaua      720

acuuauuucu cguagcugcc cacgaauucg gacacucacu agggcuagac cacagcaaag      780

accccggagc auuaauguuu ccaauuuaua cauauacagg aaaaagucac uuuaugcuac      840

cggacgacga cguacaaggc auacaaucac ucuacggucc aggagacgaa gacccaaacc      900

caaaacaccc caaaacacca gauaaaugcg acccaucacu aucauuagau gcaauaacau      960

cauuaagagg agaaacuaug auuuucaaag acagauucuu cuggagguua cacccccaac     1020

aaguagaugc agaacucuuu cuaacaaaau cauuuuggcc agaauuacca aauagaauug     1080

acgcugcaua cgaacaccca ucacacgacc uaauauuuau auucagagga agaaaauucu     1140

gggccuuaaa cggauaugac auacuagaag gauacccaaa aaaaauauca gaauuagguc     1200

uacccaaaga aguaaaaaaa auaucagcag ccguccacuu cgaagacacu ggaaaaacau     1260

uacucuuuag uggcaaccaa guauggagau augacgauac aaaccacaua auggauaaag     1320

acuacccaag auuaauagaa gaagacuuuc caggaauugg agacaaagua gacgccguau     1380

acgaaaaaaa uggauacaua uacuuuuuca acggaccaau ucaauucgaa uauuccauau     1440

ggucaaaccg aauaguuagg guaaugccag caaacuccau auuauggugu uaaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  7316
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt12)

<400>  7316
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacaccaa auacaacaga agacuaugac acaacuacag      120

aauucgacua uggcgacgcc acaccaugcc aaaaaguaaa cgaaagagca uucggcgcac      180

aauuauuacc accuuuauac ucauuaguau ucguaauagg auuaguagga aacauacuag      240

uaguauuagu acuaguacaa uacaaaagac uaaaaaacau gacauccaua uaccuacuaa      300

acuuagcaau aucugaccua cuauuccuau ucacucuacc auucuggauc gacuauaaac      360

uaaaagauga cuggguuuuc ggugacgcaa ugugcaaaau ccucucagga uuuuacuaca      420

caggauuaua cagcgaaauc uuuuucauca uacuauuaac caucgaccga uaccuagcca      480

uaguacacgc aguauucgca cucagagcca gaacaguaac uuucggcgua auaacaucaa      540

uaauaaucug ggcauuagcc auacucgcau caaugccagg acuauacuuc ucaaaaacac      600

aaugggaauu cacccaucac acaugcucau uacacuuccc ucacgaaucc uuaagagaau      660

ggaaacuauu ucaagcccua aaauuaaacu uauucggacu aguacuaccu uuacuaguaa      720

ugauaaucug uuacacagga auuauaaaaa uacuacucag aagacccaac gaaaaaaaau      780

caaaagccgu aagauuaaua uucguaauaa ugauaauuuu cuucuuauuc uggacaccau      840

acaacuuaac aauacucauu uccgucuucc aagacuucuu auucacucac gaaugcgaac      900

aaucaagaca ucuagaccua gcaguccaag ucaccgaagu aauagcauac acacacugcu      960

gcguaaaccc aguaauuuac gcauucguag gagaacgauu cagaaaauac cuuagacaac     1020

uuuuucacag aagaguagca guccaccuug ucaaauggcu accauuuuua ucuguagaca     1080

gacuagaaag aguaucuuca acaucaccau cuacaggaga acacgaacuc ucugccggcu     1140

uuuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  7317
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt12)

<400>  7317
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cgaacacuag ccugccuauu acuacuagga ugcggauacc      120

uagcacacgu acuagcagaa gaagcagaaa uaccaagaga aguaauagaa agacuagcaa      180

gaucacaaau acacaguaua agagaccuac aaagacuacu agaaauagac ucaguaggau      240

cagaagacuc acuagacaca ucacuaagag cacacggcgu acaugcaaca aaacacguac      300

ccgaaaaaag accauuacca auaagaagaa aaagaagcau agaagaagcc guaccagcag      360

uauguaaaac aagaacagua auauacgaaa uaccaagaag ccaaguagac ccaacaucag      420

ccaacuucuu aauauggcca ccaugcguag aaguaaaaag augcacagga ugcugcaaca      480

caagcagcgu caaaugccaa ccaaguagag uacaccaucg aucaguaaaa guagcaaaag      540

uagaauacgu cagaaaaaaa ccaaaacuaa aagaaguaca aguaagacuc gaagaacacc      600

uagaaugcgc augcgccaca acaagccuaa acccagacua cagagaagaa gacacaggaa      660

gaccaagaga aucaggaaaa aaacgaaaaa gaaaaagacu aaaaccaacu uaaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  7318
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt12)

<400>  7318
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagaugcu gggcacuauu ccuaucauua ugcuguuacu      120

uaagacuagu aucagcagaa ggagauccaa uaccagaaga auuauacgaa auguuaagug      180

aucacucaau aagaagcuuu gacgauuuac aaagacuacu acauggagau ccaggagaag      240

aagacggagc agaacuugau cuaaauauga caagaucaca caguggagga gaauuagaau      300

cacuagccag aggaagaaga agucuaggau cacucacaau cgcagaacca gcaaugauag      360

cagaauguaa aacaagaaca gaagucuucg aaaucucaag acgacuaaua gacagaacaa      420

augcaaacuu cuuaguaugg ccaccaugcg uagaaguaca aagaugcuca ggaugcugca      480

auaacaggaa cguacaaugu agaccaacac aaguacaacu aagacccgug caaguaagaa      540

aaauagaaau aguaagaaaa aaaccaaucu uuaaaaaagc aacaguaaca cuagaagauc      600

aucuagcaug caaaugcgaa acaguagcag cugcaagacc aguaacaaga ucaccaggag      660

gaagccaaga acaaagagca aaaacgccac aaacaagagu aacaauaaga acaguuagag      720

uaagaagacc accaaaagga aaacauagaa aauucaaaca cacacacgau aaaacagcau      780

uaaaagaaac auuaggagca uaaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  7319
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt12)

<400>  7319
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucauuauucg gauuauuacu uuuaacaucu gcauuagcag      120

gacaaagaca aggaacacaa gcagaaucaa accuaucaag caaauuucaa uuuucaucaa      180

auaaagaaca aaauggcgua caagauccac aacacgaaag aauaauaaca guaagcacua      240

acggaucaau acacagcccc cgauucccac auacauaccc aagaaacaca guauuaguau      300

ggagauuagu cgccguagaa gaaaauguau ggauacaacu uacauucgau gaaagauucg      360

gauuagaaga ccccgaagac gacauaugca aauacgacuu cguagaagua gaagaacccu      420

cagacggaac aauauuaggu cguuggugcg gaucaggaac aguaccagga aaacaaauaa      480

guaaaggaaa ccaaauaaga auucgauucg uaucagauga auacuuucca ucagaaccag      540

gauucugcau ccauuacaau auaguaaugc cacaauuuac agaagcagua ucaccaagcg      600

uauuaccacc aucagcccua ccucuagacu uauuaaauaa cgcaauaaca gcauuuagca      660

ccuuagaaga cuuaauacga uacuuagaac cagaacgaug gcaacuagac cuugaagacc      720

uauacagacc aacauggcaa uuacuaggaa aagcauucgu cuuuggcaga aaaucaagag      780

uaguagaucu aaaccuacua acagaagaag uaagauuaua caguugcaca ccuagaaacu      840

ucucaguaag cauaagagaa gaacuaaaaa gaacagacac cauauucugg ccaggaugcc      900

uacuaguuaa aagaugcgga ggaaauugcg cauguugcuu acacaacugu aacgaaugcc      960

aaugcguacc cucaaaagua acaaaaaaau accacgaagu acuacaauua agaccaaaaa     1020

caggaguaag aggacuccac aaaucacuua cagacguagc acuagaacac cacgaagaau     1080

gugacugcgu augcagaggc ucaaccggag gauaaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  7320
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt12)

<400>  7320
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauagauuaa uauucguaua cacacuaaua ugugcaaacu      120

ucugcucaug cagagacacc agugcaacac cccaaagcgc aucaauaaaa gcacuacgaa      180

acgcaaacuu aagaagagac gaucuauaua gaagagauga aacaauacaa guaaaaggaa      240

acggauacgu acaaucacca cgauuuccaa auucauaccc acgaaaccua uuauuaacau      300

ggcgacuaca cucacaagaa aauacaagaa uacaacuugu cuucgacaac caauucggac      360

uagaagaagc agaaaaugac auaugcagau augacuucgu agaaguagaa gacauaucag      420

aaacuucaac aauaauaaga ggaagauggu guggacacaa agaaguccca ccaagaauaa      480

aaucaagaac aaaccaaaua aaaauaaccu ucaaaucaga ugacuacuuc guagcaaaac      540

cgggcuuuaa aauauacuau agccuauuag aagacuucca accagcagca gcaucagaaa      600

ccaacuggga aucaguaaca agcucaauau cuggaguauc auacaacuca ccaucaguaa      660

cagauccaac acuaauagca gacgcauuag acaaaaaaau agccgaauuc gacacaguag      720

aagaucuacu aaaauacuuc aacccagaau cauggcaaga agaccuagaa aacauguacc      780

uagacacacc aagauacaga ggaagaucau accaugacag aaaaaguaaa guagaccuag      840

acagacuaaa cgacgaugca aaaagauaca gcugcacacc aagaaauuac ucaguaaaca      900

uaagagaaga acuaaaacua gcaaacguag uauucuuccc aagaugcuua uuaguacaaa      960

ggugcggagg aaauugugga ugcggaacag uaaacuggag auccuguaca ugcaacucag     1020

gcaaaacagu caaaaaauac cacgaaguac uacaauucga accaggacac auaaaaagaa     1080

gaggcagagc aaaaacaaug gcacuaguag acauacaacu cgaucaccac gaaagaugcg     1140

acuguauaug cucaagcaga ccaccacgau aaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  7321
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt12)

<400>  7321
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaacacacu caaaauuccc agcagcagga augucacgac      120

cucuagacac aucauuacga cuaaaaacau ucucaucaaa aucugaauac caacuaguag      180

uaaacgcagu aagaaaauua caagaaucag gauucuacug gucagcagua acaggaggag      240

aagcaaaccu acuauuauca gcagaaccag caggaacauu ccuaauaaga gacucaucag      300

accaaagaca cuucuuuaca cuaucaguaa aaacccaauc uggaacaaaa aaccuacgaa      360

uacaauguga aggaggaucc uucucucuac aaucagaccc aagaucaaca caaccaguac      420

ccagauuuga cugcguacua aaauuaguac accacuacau gcccccaccc ggagcaccau      480

cauucccauc acccccaaca gaacccucau cagaaguacc agaacaacca ucagcacaac      540

cacuaccagg cucaccacca agaagagcuu auuacauaua cuccggagga gaaaaaauac      600

cacuaguucu aucaagaccc uuaucaucaa acguagccac acuacaacac cuaugcagaa      660

aaacaguaaa cggacacuua gacucauacg aaaaaguaac acaacuucca ggaccaauaa      720

gagaauucuu agaucaauac gacgcaccau uauaaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  7322
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt12)

<400>  7322
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaccaucag caggacaauu agcauuauuc gcauuaggaa      120

uaguauuagc agcaugucaa gcauuagaaa auucaacauc accauuauca gcagacccac      180

caguagcagc agcaguagua ucacauuuua augauugccc agauucacau acacaauucu      240

gcuuucaugg aacauguaga uuuuuaguac aagaagauaa accagcaugu guaugucauu      300

caggauaugu aggagcaaga ugugaacaug cagauuuauu agccguagua gcagcaucac      360

aaaaaaaaca agcaauaaca gcauuaguag uaguaaguau aguagcauua gcagucuuaa      420

uaauaacaug uguauuaaua cauuguuguc aaguaagaaa acauugugaa uggugcagag      480

cauuaauaug uagacaugaa aaaccaucag cacuauuaaa aggaagaaca gcauguuguc      540

acucagaaac aguaguauaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  7323
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt12)

<400>  7323
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaccaagug gauuaagacu acuaccauua cuauuaccac      120

uauuauggcu acuaguauua acaccuggaa gaccagcugc aggccuauca accugcaaaa      180

caauagacau ggaacuagua aaacgaaaaa gaauagaagc aauaagaggc caaauacuau      240

caaaacuaag auuagcauca ccaccuuccc aaggagaagu accaccaggc ccacuaccag      300

aagcaguacu agcacuauac aacuccacaa gagacagagu agcaggcgaa ucagccgaac      360

cagaaccaga accagaagcu gacuacuacg caaaagaagu aacuagagua uuaaugguag      420

aaacacacaa cgaaaucuau gacaaauuua aacaaucuac acauucuaua uauauguucu      480

ucaauacaag cgaauuacga gaagcaguac ccgaaccagu acuauuauca agagcugaac      540

uccgauuacu aagauuaaaa cuaaaaguag aacaacacgu agaacuauac caaaaauauu      600

cuaauaauuc auggagauau cuuagcaaua gauuacuagc accauccgac ucaccugaau      660

ggcuaucauu ugauguaaca ggaguaguac gucaauggcu aucacgaggc ggagaaauag      720

aaggauuuag auuaagcgcu cacugcagcu gugacucaag agacaacaca uuacaaguag      780

acaucaacgg auucacaaca ggaagaagag gagaucuagc cacaauacac ggaaugaaca      840

gaccauuucu acuauuaaug gcaacaccac uagaaagagc acaacaucua caaucuucaa      900

gacacagaag agcauuagac acaaacuacu gcuuuucaag cacagaaaaa aauugcugcg      960

ucagacaauu auauauagau uucagaaaag auuuaggcug gaaauggaua caugaaccaa     1020

aaggauacca cgcaaacuuc ugccuaggac caugcccaua cauuugguca uuagauaccc     1080

aauacucaaa aguucuugca uuauacaacc aacacaaccc uggagcaagu gcagcaccau     1140

guugcguacc ccaagcauua gaaccacuac caauaguaua uuacguuggc cgaaaaccca     1200

aaguagaaca acuaucaaac augauaguca gaucauguaa auguucauaa ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  7324
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt12)

<400>  7324
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuacugcg uacucucagc cuuccuaaua cuacaccuag      120

uaacaguagc auuaagcuua ucaacaugcu caacacuaga cauggaucaa uucaugagaa      180

aaagaauaga agcaauaaga ggccaaauac uaucaaaacu uaaauuaaca ucaccaccag      240

aagacuaucc cgaaccagaa gaaguaccac cagaaguaau aucaauauau aacucaacaa      300

gagaccuauu acaagaaaaa gcaagccgaa gagcagcagc augcgaacga gaaaggucag      360

acgaagaaua cuacgccaaa gaaguauaca aaauagacau gccacccuuc uucccaucag      420

aaaaugccau accccccaca uuuuacagac cauacuucag aaucguaaga uucgacguau      480

cagcaaugga aaaaaacgca ucaaaucuag uuaaagcaga auucagagua uucagacuac      540

aaaacccaaa agcaagagua ccagaacaaa gaauagaacu auaccaaaua cuuaaaucca      600

aagaucuaac aucaccuaca caaagauaua uagacucaaa aguaguaaaa acuagagcag      660

aaggcgaaug gcuauccuuc gacguaacag acgccguuca cgaauggcuu caccacaaag      720

accgaaacuu aggauucaaa auaucacuuc acuguccaug uugcacauuu guccccucaa      780

auaacuacau aauccccaau aaaucagaag aacucgaagc aagauucgcc ggaauagacg      840

gaacuagcac auauaccucc ggagaccaaa aaaccauaaa aucuacaaga aaaaaaaacu      900

cuggaaaaac accacacuua cuauuaaugc uacuacccuc auaccgacuc gaaucucaac      960

aaacaaacag acgaaaaaaa agagcauuag acgccgcuua uuguuucaga aauguacaag     1020

auaacugcug ccuacgacca cuauacauag auuucaaaag agaucuaggc uggaaaugga     1080

uccaugaacc aaaaggcuau aacgcaaacu ucugcgcugg agcaugccca uaccuauggu     1140

caucagacac acaacauuca agaguauuau cacuuuacaa caccauaaau cccgaagcau     1200

cagcaagccc cuguugcgua ucacaagacc uagaaccacu aaccauccua uacuauauag     1260

gaaaaacucc aaaaauagaa caacuaucua auaugauagu aaaaucaugc aaaugcucuu     1320

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  7325
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt12)

<400>  7325
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaugcacu uacaaagagc ccuaguaguc cuagcuuuac      120

uuaacuucgc aaccguaucc cuaagccuau caacuuguac aacccuagac uuuggacaca      180

uaaaaaaaaa acgcguagaa gcaauuagag gacaaauauu aucuaaacua agauuaaccu      240

caccaccaga accaacagua augacacaug uaccauacca gguauuagca cuauacaauu      300

caacacgcga acuacuagag gaaaugcaug gagaaagaga agaaggaugc acacaagaaa      360

acacagaauc agaauacuac gcaaaagaaa uccauaaauu cgacaugaua caaggauuag      420

cagaacacaa cgaacuagca guaugcccaa aaggaauaac aucaaaagua uuuagauuca      480

auguaucuuc aguugaaaaa aauagaacua accucuuuag agccgaauuc cgcguauuaa      540

gaguccccaa cccaagcagc aaacgaaacg aacaaagaau agaacuauuc caaauacuaa      600

ggccagacga acacauagca aaacaaagau auauaggagg caaaaauuua cccacaagag      660

guacagcaga auggcuauca uucgauguaa cagauaccgu aagagaaugg cuacuaagaa      720

gagaaaguaa ucuaggccua gaaauaucaa uacauugucc augucacaca uuccaaccaa      780

acggagacau auuagaaaac auacacgaag uaauggaaau aaaauucaaa ggaguagaca      840

acgaagauga ucacggacga ggcgaucuag gcagauuaaa aaaacaaaaa gaccaccaca      900

auccacaccu aauauuaaug augauaccac cacacagacu agacaaucca ggccagggag      960

gccaaagaaa aaaaagggca cuagacacca acuacugcuu cagaaaccua gaagaaaacu     1020

gcugcguaag accacuauac auugacuuca gacaagaccu aggcuggaaa uggguccaug     1080

aaccaaaagg auacuacgcc aacuuuugcu caggaccaug cccauaccuc agaucagcag     1140

acacaaccca cucaacagua uuagguuuau acaacacauu aaacccagaa gcaagugccu     1200

ccccuuguug cguaccacaa gaccuagaac cauuaaccau auuauauuau guaggacgaa     1260

caccaaaagu agaacaacua ucaaauaugg uaguaaaauc augcaaaugu agcuaaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  7326
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt12)

<400>  7326
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcuccuguag ccguaugggc agcucuagcc guaggauuag      120

aauuaugggc ugcugcccau gcacuaccug cccaaguugc uuuuacacca uacgcaccag      180

aaccugguuc aacauguaga uuaagagaau auuaugauca aacugcucaa auguguuguu      240

caaaauguag cccuggucaa caugccaaag uauucuguac uaaaacuucu gauaccguau      300

gugauucaug ugaggauuca acauauacac aauuauggaa uuggguacca gaauguuuau      360

cauguggauc ucgauguuca ucagaucaag uagaaacaca agcuuguaca agagaacaaa      420

auagaauaug uacuuguaga ccagguuggu acugcgccuu aucaaaacaa gaaggaugua      480

gacuaugcgc cccacuacga aaauguagac caggauuugg uguugcacgu ccaggaacag      540

aaacaucaga cguaguaugu aaaccaugcg cucccgguac auucucaaau acaacaucau      600

ccaccgauau augucgacca caucaaauau guaauguagu agcaauacca ggaaaugcau      660

cuauggacgc aguauguaca ucaacaucac ccacaagauc aauggcacca ggugcugucc      720

aucuaccaca accuguuuca acaagaucac aacauacaca accuacaccc gaaccaucca      780

cagcaccaag uaccucauuu cuuuuaccua ugggaccauc accaccugca gaaggaucaa      840

caggagauuu ugcacuucca guaggacuaa uaguuggagu aacugcacua ggauuauuaa      900

uaauuggagu cguaaauugu guaauaauga cacaaguaaa aaaaaaacca uuaugcuuac      960

aacgagaagc caaagucccu cauuuaccag cagacaaagc uagaggaacc caaggaccag     1020

aacaacaaca ccuacucaua accgcaccuu caucaucuuc aucaucuuua gaaucaucug     1080

caucugcauu agauagaaga gcacccacaa gaaaucaacc acaagcaccu ggaguugaag     1140

cuuccggggc aggugaagcu cgagcuucaa caggaucuuc agauucaucu ccaggugguc     1200

auggaaccca aguuaaugua acuugcaucg uaaauguaug uucaucauca gaucacucau     1260

cacaauguuc aucacaagca aguucaacua ugggagauac ugacucaagc ccaucggaau     1320

caccuaaaga ugaacaagua ccauuuagua aagaagaaug ugcauuuaga ucucaacuug     1380

aaacaccaga aacuuuauua ggaaguacag aagaaaaacc acuaccauua ggaguacccg     1440

augcagggau gaaaccuucc uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  7327
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt12)

<400>  7327
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaguaauga ggcuauuucc auguuuuuua caauuacuag      120

caggauuagc auuaccagca guaccaccac aacaaugggc auuaagugca ggaaauggaa      180

guucagaagu agaaguagua ccauuucaag aaguaugggg aagaucauau uguagagcac      240

uugaaagauu aguagaugua guaagugaau auccaagcga aguagaacau auguuuucac      300

caucaugugu aaguuuauua agauguacag gauguugugg agaugaaaau cuacauugug      360

uaccaguaga aacagcaaau guaacaaugc aauuacuaaa aauaagaagu ggagauagac      420

caucauaugu agaauuaaca uucagucaac auguaagaug ugaauguaga ccauuaagag      480

aaaaaaugaa accagaaaga agaagaccaa aaggaagagg aaaaagaaga agagaaaaac      540

aaagaccaac agauugccau uuauguggag augcaguacc aagaagauaa ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  7328
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt12)

<400>  7328
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagacagac aaacagauac agcaccuuca ccaagcuauc      120

acuuauuacc ugguagaaga agaacaguag augcagcagc uaguagggga caaggaccag      180

aaccagcucc aggaggaggu guagaaggag uaggggcaag aggaguagcu uuaaaauuau      240

uuguacaacu uuuaggaugu agcagguuug gaggagcggu uguaagagcc ggugaagcag      300

aaccgucagg agcagcaaga ucagcaagcu caggaaggga agaaccacaa ccagaagaag      360

gugaagaaga agaagaaaag gaagaagaaa ggggaccaca auggcgacug ggagcaagaa      420

agccagguag uuggacagga gaagcagcag uaugcgcaga cucugcacca gcagcaagag      480

caccgcaagc auuagcucga gcaaguggaa ggggaggaag aguagcucga agaggagcag      540

aagaaucagg accuccacac aguccaagua ggagaggaag ugcaagcagg gcaggaccag      600

ggagagcaag cgaaacaaug aauuuucuau ugaguugggu acauuggagc cuagcccuau      660

uauuauauuu acaucaugcu aaauggucac aagcagcacc aauggcagaa ggaggaggac      720

aaaaucauca ugagguagug aaauuuaugg auguauauca aagaucauau ugucauccaa      780

uagaaacauu aguugacaua uuucaagaau auccagauga aauagaauau aucuuuaaac      840

cuagcugugu cccauugaug agauguggag gauguuguaa ugaugaggga uuagaaugcg      900

uaccaacaga agaaaguaac auaacaaugc aaauaaugcg aauaaaacca caucaaggac      960

aacauauagg agaaauguca uuuuugcaac auaacaaaug cgaaugcagg ccaaaaaaag     1020

acagagcaag acaagaaaaa aaaaguguua gaggaaaagg aaaaggucaa aaaaggaaaa     1080

gaaaaaaaag uagauauaaa aguuggagug uauauguagg agcaagaugu uguuuaaugc     1140

cauggagucu accgggacca cauccaugug gaccuugcag ugagaggaga aaacacuuau     1200

uuguucaaga cccacaaaca uguaaauguu cuuguaaaaa cacugauagc agauguaaag     1260

cucgacaauu ggaauuaaau gaaaggacau guagauguga uaaaccaaga agauaaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  7329
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt12)

<400>  7329
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuuccuau uaagcugggu acacugguca cuagcauuau      120

uauuauauuu acaucacgcc aaauggucac aagcagcacc aauggcagaa ggaggaggac      180

aaaaccacca cgaaguagua aaauuuaugg auguauacca aagaagcuau ugccauccaa      240

uagaaacacu aguagacaua uuccaagaau auccagauga aauagaauau auauuuaaac      300

cauccugcgu accauuaaug agaugcggag gaugcugcaa cgacgaagga cuagaaugcg      360

uaccaacaga agaaaguaau auaacaaugc aaauaaugag aauaaaacca caccaaggac      420

aacacauagg cgaaaugagu uucuuacaac auaacaaaug cgaaugcaga ccaaaaaaag      480

acagagcaag acaagaaaaa aaaagcguaa gaggaaaagg aaaaggacaa aaaagaaaaa      540

gaaaaaaaag cagauacaaa agcuggagcg uauacguagg agcaagaugc ugcuuaaugc      600

cauggucacu accaggacca cacccaugcg gaccauguuc agaaagaaga aaacaucuau      660

uuguacaaga cccacaaaca uguaaaugcu caugcaaaaa caccgacagu agauguaaag      720

caagacaacu agaacuaaau gaaagaaccu guagauguga caaaccaaga agauaaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  7330
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt12)

<400>  7330
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaccacuau uaagaagacu acuauuagca gcauuacuac      120

aacuagcacc agcacaagcu ccaguaagcc aaccagacgc acccggacau caaagaaaag      180

uaguaucaug gauagaugua uacacaagag caacauguca accaagagaa guuguagucc      240

cacuaacagu agaauuaaug ggaacaguag caaaacaauu aguaccauca ugcguaaccg      300

uacaaagaug cggaggaugu ugcccagacg auggcuuaga augcguacca acuggacaac      360

aucaaguaag aaugcaaaua cuaaugauaa gauacccauc aucacaauua ggagaaaugu      420

cauuagaaga acauucacaa ugcgaaugca gaccaaaaaa aaaagacuca gcaguaaaac      480

cagacagagc agcaacacca caucauagac cacaaccaag aucaguacca ggaugggacu      540

cagcaccagg agcaccaucu ccagcagaca uaacacaucc aacaccagca ccaggaccau      600

cagcacaugc agcacccuca acaacaagug cacuaacacc aggaccagca gcagcagcag      660

cugacgcagc agcaucauca gucgcaaaag gaggagccua aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  7331
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt12)

<400>  7331
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccuauuag gauucuuuag cguagcgugc aguuuauugg      120

cagcagcacu auuaccaggu ccacgugaag caccagccgc agccgcagcu uucgaaucag      180

gauuagacuu aagcgacgcu gaacccgacg caggcgaagc aacagcauac gcuucaaaag      240

aucuagaaga acaacuaaga ucuguaucuu caguagacga auuaaugaca guacuauacc      300

cagaauauug gaaaauguau aaaugccaac uaagaaaagg agguuggcaa cacaauagag      360

aacaagcaaa cuuaaacucc agaacagaag agacuauaaa auuugcagca gcacauuaca      420

acacagaaau ucuaaaauca auagacaaug aauggagaaa aacucaaugu augccaagag      480

aaguaugcau agacguaggu aaagaauucg guguagccac caacacauuu uuuaaaccac      540

caugcguauc aguauauaga ugcggaggcu guugcaauuc agaaggauua caauguauga      600

auaccucuac aagcuaccua ucaaaaacac uauucgaaau aacuguacca uuaucacaag      660

gaccaaaacc aguaacaaua ucauuugcaa accacacauc augucgaugc augucaaaau      720

uagacguaua ccgacaagua cacaguauaa uaagaagauc acuacccgca acacuaccac      780

aaugccaagc agcaaauaaa acaugcccaa cuaacuacau guggaauaau cauauuugua      840

gaugccuagc acaagaagau uucauguucu caagugaugc aggugacgac ucuacugacg      900

gauuucauga cauaugugga ccaaauaaag aacuagacga agaaacaugu caaugcguau      960

gcagagcagg acuucgacca gcauccugug guccacauaa agaacuagau agaaauucau     1020

gccaaugugu uuguaaaaau aaauuauucc ccagccaaug cggagcaaau agagaauuug     1080

augaaaauac augccaaugu guauguaaaa gaaccugccc aagaaaucaa ccacuaaacc     1140

caggaaaaug cgccugcgaa ugcacagaaa guccacaaaa augucuauua aaagguaaaa     1200

aauuccauca ccaaacaugu ucaugcuaca gaagaccaug cacaaacaga caaaaagcau     1260

gugaaccugg auuuucauau ucagaagaag uuuguagaug uguuccauca uacuggaaac     1320

gaccacaaau gagcuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  7332
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt12)

<400>  7332
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uacagagaau ggguaguagu aaacguauuc augaugcuau      120

auguacaacu uguacaagga agcucaaaug aacacggacc aguaaaaaga ucaucacagu      180

ccacacuaga aagaucagaa caacaaauaa gagcagcauc cucucuagaa gaauuacuaa      240

gaaucacaca uuccgaagac uggaaauuau ggcgaugucg acuacgcuua aaaagcuuua      300

cuaguaugga cucacgcuca gcaucacaua gaaguacaag auuugcagca acauucuacg      360

acauagaaac acuaaaagua auagaugaag aauggcaaag aacacaaugc ucaccaagag      420

aaacaugcgu cgaaguagca ucugaacucg gaaaauccac caauacauuc uucaaaccac      480

caugcguuaa cguauuuaga ugcggaggau guugcaacga agaaucacua auaugcauga      540

auacauccac aucauacaua ucaaaacaac uauucgaaau auccguacca uuaacaucag      600

uaccagaacu aguaccagua aaaguagcaa aucacacagg augcaaaugc cuaccaacag      660

caccaagaca cccuuacagc auaauaagaa gaucaauaca aauacccgaa gaagacagau      720

gcucccacag caaaaaauua ugcccaaucg acaugcuaug ggacucaaac aaaugcaaau      780

gcguacuaca agaagaaaac ccacuagcag guacagaaga ccacucacac cuacaagaac      840

cagcauuaug cgguccucac augauguucg acgaagauag augcgaaugc guaugcaaaa      900

caccaugucc aaaagacuua auacaacacc caaaaaauug cuccuguuuu gaauguaaag      960

aaucacuaga aacaugcugc caaaaacaca aauuauuuca ucccgauaca ugcucaugcg     1020

aagacagaug cccauuccac acaagaccau gcgcaagugg aaaaacagcc ugcgccaagc     1080

acugccgauu cccaaaagaa aaaagagcag cucaaggacc acacucacga aaaaauccau     1140

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  7333
<211>  906
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_061986.1__HsFGF21 (opt13)

<400>  7333
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacucagacg aaacagguuu cgaacacucc ggauuauggg      120

uaucaguauu agcaggauua cuauuaggag caugccaagc acauccaaua ccagacucau      180

caccacuucu acaauucgga ggacaaguaa gacaaagaua cuuauacaca gaugacgccc      240

aacaaacaga agcacacuua gaaauaagag aagacggcac agucggagga gcagcagacc      300

aaucaccaga aucuuuauua caauuaaaag cauuaaaacc aggaguaaua caaauauuag      360

gaguaaaaac aucaagauuu cuaugccaaa gaccagacgg agcauuauac ggaucauuac      420

auuucgaccc agaagcaugu ucauucagag aauuauuacu agaagauggu uauaauguau      480

aucaaucuga agcacacgga uuaccacuac aucuaccagg aaauaaauca ccacauagag      540

acccagcacc aagaggacca gcaagauucu uaccauuacc cggauuaccu ccagcacuac      600

cugaaccacc aggaauacua gcaccacaac caccagaugu aggaucaucc gacccauuau      660

caaugguagg accaucacaa ggaagaaguc caucauacgc aucauaagga cuagucccug      720

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      900

agaauu                                                                 906


<210>  7334
<211>  1686
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1 (opt13)

<400>  7334
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacucauucc cuccacuauu auuauuacua uuuuggggag      120

uaguaucaca caguuucccu gcaaccuuag aaacacaaga acaagacgua gaccuaguuc      180

aaaaauacuu ggaaaaauac uacaaccuua aaaaugacgg aagacaagua gaaaaacgaa      240

gaaauucagg accagucgua gaaaaacuaa aacaaaugca agaauuuuuc ggacuaaaag      300

uuacaggaaa accagaugca gaaacacuaa aaguaaugaa acaaccuaga uguggaguac      360

ccgacguagc ccaauuugua uuaacagaag gcaacccaag augggaacaa acccacuuaa      420

ccuacagaau agaaaauuac acaccagauc uaccuagagc cgacguagau caugcgauag      480

aaaaagcauu ucaauuaugg aguaauguaa cuccacuaac auuuacaaaa gucucagaag      540

gacaagcgga cauaaugaua uccuucguaa gaggagauca cagagacaau aguccauucg      600

acggaccagg cggaaaccua gcacacgcuu uccaaccagg acccggcaua ggaggagaug      660

cacacuucga cgaagacgaa agauggacaa acaacuucag agaauauaac cuccacagag      720

uagcugcaca ugaacuagga cauucauuag gacuuagcca cagcacagac auaggagcac      780

uaauguaccc uucauauaca uuuucaggag acguacaauu agcacaagac gauauagacg      840

gaauacaagc aauauaugga agaucacaaa auccuguaca accgaucgga ccucagacac      900

caaaagcaug cgauagcaaa cuuaccuucg acgcuauaac aacaauuaga ggcgaaguaa      960

uguucuucaa agaccgauuu uacaugagaa caaauccauu cuaucccgaa guagaauuaa     1020

acuuuauauc cguauuuugg ccacaacucc cuaacggauu agaagccgca uacgaauuug     1080

cagauagaga cgaaguaaga uuuuucaaag gaaacaaaua cugggcugua caaggacaaa     1140

acguacuaca cggauaucca aaagacauau acucaucauu cggcuuuccc cgaacaguaa     1200

aacauauaga ugcagcauua ucagaagaaa acacaggaaa aacauauuuc uuuguagcca     1260

acaaauacug gagauaugau gaauacaaaa gaucaaugga cccagguuac ccaaaaauga     1320

uagcacauga uuuuccagga auuggacaua aagucgacgc cgucuucaug aaagacggau     1380

ucuucuauuu cuuucaugga acuagacaau auaaauucga cccaaaaaca aaaagaauau     1440

uaacacuaca aaaagcaaac ucuugguuca acuguaggaa aaauuaagga cuagucccug     1500

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1680

agaauu                                                                1686


<210>  7335
<211>  1446
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002412.1__HsMMP1(1-19,100-469) (opt13)

<400>  7335
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacucauuuc caccauuacu acucuuauua uuuuggggag      120

uaguaucaca cucauucgua cuaacagaag gaaauccaag augggaacaa acacaccuua      180

ccuacagaau agaaaauuac acaccagauc uaccaagagc agacguagac cacgcaauag      240

aaaaagcauu ucaauuaugg ucaaacguaa caccauuaac auucacaaaa guaucagaag      300

gacaagcaga cauaaugaua ucauucguaa gaggagacca cagagacaau ucaccauuug      360

auggaccagg agguaaucug gcacacgcau uccaaccagg accaggaaua ggaggagacg      420

cacacuucga cgaagacgaa agauggacaa acaacuucag agaauacaac cuacacagag      480

uagcagccca ugaacuagga cacucacuag gacuaucaca cucaacagac auaggagccc      540

uaauguaucc auccuacaca uucucaggag acguacaacu cgcgcaagac gacauugacg      600

gaauccaagc uauauacgga agaucacaaa acccaguaca accaauaggc ccccaaacac      660

caaaagcaug ugacucaaaa cuaacauuug augcaauaac aacaauaaga ggcgaaguaa      720

uguucuucaa agacagauuc uacaugcgca caaauccauu cuacccagaa gucgaauuaa      780

acuucauauc aguauucugg ccccaauuac caaacggauu agaagccgcc uacgaauuug      840

cagaccgaga cgaaguaaga uucuucaaag gaaacaaaua uugggcagua caaggacaaa      900

acguauuaca cggauaucca aaagacauau acuccucauu uggcuuucca agaacaguaa      960

aacauaucga cgcagcacuc uccgaagaaa acacaggaaa aacauacuuc uuuguagcaa     1020

acaaauacug gagauaugac gaauauaaaa gaucaaugga cccgggauac ccaaaaauga     1080

uagcacauga cuucccagga auaggacaca aaguagacgc cguauucaug aaagacggau     1140

uuuucuacuu cuuucacgga acuagacaau acaaauucga cccaaaaaca aaaaggauac     1200

uaacauuaca aaaagcaaac ucaugguuua acugccgcaa aaacuaagga cuagucccug     1260

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1320

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1440

agaauu                                                                1446


<210>  7336
<211>  3633
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA77453.1__ColG (opt13)

<400>  7336
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aagaaaaaua uacuuaaaau acucauggac ucauacagua      120

aagaaagcaa aauucaaacg guucgaagag uaaccagugu cagccuauua gcaguauauc      180

uaacuaugaa uacuagcagc uuaguacucg cgaaaccaau ugaaaauaca aaugacacaa      240

guauuaaaaa uguagaaaaa uugagaaaug caccaaauga agaaaacucg aagaaaguag      300

aagauagcaa aaaugauaaa guugagcaug uuaaaaacau agaagaagca aaagucgaac      360

agguggcucc agaaguaaaa ucaaaaagca cacucagauc agcaaguauc gcaaacacga      420

acagugagaa auaugauuuu gaauaccuga auggccucuc auauacagaa uuaacaaacu      480

uaauuaaaaa uauaaaaugg aaucaaauca acggcuuauu caauuacagu accggaaguc      540

agaaauucuu uggggacaaa aaccgaguac aagcaauaau uaaugcauua caagaaucag      600

ggcgaacaua uacagccaac gauaugaaag gaauugaaac auucaccgag guuuuacgag      660

cuggcuucua uuugggcuac uacaacgaug gacuauccua uuugaacgau agaaacuuuc      720

aggauaaaug uauaccagca augaucgcaa uacagaagaa cccaaacuuc aaauuaggaa      780

cagcaguaca agaugaagua auuaccaguc uugguaaauu aauuggaaac gcaagcgcga      840

augcugaagu uguaaauaac ugugucccag ucuuaaaaca auuuagagag aauuuaaauc      900

aauaugcacc agauuacguu aaaggaacag cgguuaauga auuaauaaaa ggaauagagu      960

ucgacuuuag cggagcagcu uacgaaaaag acguaaaaac uaugccuugg uacggaaaga     1020

uugauccauu cauaaacgaa uuaaaagcau ugggccucua cggaaauaua acaucagcua     1080

cagaaugggc cagcgaugug gguauauacu aucuuaguaa auucggucuu uauaguacaa     1140

acaggaauga uaucguucaa ucacuagaaa aagcaguaga uauguauaaa uacggaaaaa     1200

uagcauuugu ggcaauggaa agaauaacau gggacuauga uggaauagga ucuaacggca     1260

agaaaguaga ccaugacaaa uuucucgacg augccgaaaa acacuacuua ccaaaaacgu     1320

auacauuuga caauggaaca uuuaucauaa gagcggguga caaaguaagu gaagagaaaa     1380

uaaaaagacu auacugggca ucuagagaag uaaaaucuca auuucacagg gucgucggga     1440

augacaaagc acuagaagua ggaaacgccg acgauguccu cacaaugaaa auauucaaca     1500

gccccgaaga auauaaauuc aauacuaaua uaaauggagu uagcacagac aauggcggau     1560

uauauauaga accacgaggg acuuucuaca cguaugaaag aacaccacaa caaucaauau     1620

ucagcuuaga agaacuguuu agacaugaau auacucauua cuuacaagcu cgauauuuag     1680

uggauggauu auggggacaa ggccccuucu acgagaaaaa cagacuaacu ugguucgacg     1740

aaggaacagc agaguucuuc gccggcucaa ccaggacauc aggagugcuu ccgagaaaau     1800

caauacuagg cuaucuugca aaagauaaag uagaccacag auacagccuc aagaaaacau     1860

uaaauucagg auaugaugau agcgauugga uguuuuauaa uuauggguuu gcuguagccc     1920

acuauuuaua ugaaaaagau augccaacau uuauaaaaau gaauaaagca auucuaaaua     1980

ccgacguuaa aagcuaugau gaaauaauaa agaaauuauc agacgacgcg aacaaaaaca     2040

cagaauauca aaaucacaua caagaauuag ccgacaaaua ucaaggagca ggcauacccu     2100

uagugucaga cgacuauuua aaagaucaug gauauaagaa agcguccgaa guauauucug     2160

aaauaucuaa agcggcaagc cuaacaaaua cauccguaac agcggaaaaa ucacaauacu     2220

uuaauacauu uacacuaaga ggaacauaua caggagaaac aaguaaaggc gaauuuaaag     2280

acugggacga aaugagcaag aaacuggacg gaacacuaga aagccuagcu aaaaacucau     2340

ggagcggaua uaaaacauua acggcauauu uuaccaauua ccgaguaacg uccgacaaca     2400

aaguacaaua ugacguugua uuucacggcg uuuuaacaga uaacgcagau auaaguaaua     2460

acaaagcacc aauagcaaaa guuacaggcc caucgacagg ugccguaggu agaaacauug     2520

aauuuucugg aaaagauuca aaagaugaag auggaaaaau cguaucauac gacugggacu     2580

uuggagacgg agcaacauca agagggaaaa auucagucca ugcauacaag aaagcuggaa     2640

cauauaacgu aacauuaaaa guuaccgaug auaaaggugc gacagcaacu gaaucuuuua     2700

caaucgaaau caaaaacgaa gauacaacaa caccaauaac gaaagaaaug gaacccaaug     2760

acgauauaaa agaagcuaau ggaccaauag ucgaaggagu aaccgucaaa ggugaccuaa     2820

acggcuccga cgacgcugau acauucuauu uugauguuaa agaagaugga gaugugacaa     2880

uagaacuacc auauucagga ucuaguaacu uuaccuggcu gguauauaaa gaaggcgaug     2940

aucaaaauca uaucgcuagu gguauagaca aaaauaacag caaaguugga acauuuaaaa     3000

gcacaaaagg uagacauuac guauucauuu acaaacacga uucagcauca aauaucucau     3060

acucuuuaaa uauaaaaggc uuagguaaug aaaaacugaa agagaaagaa aauaaugauu     3120

cgucagacaa agcuacagug auaccaaauu ucaauacaac uaugcaagga ucacugcuag     3180

gagaugacag ccgugauuau uacagcuucg aaguaaaaga agaaggagag guaaacaucg     3240

aauuagauaa gaaagaugaa uuuggaguaa cauggacauu acauccagaa uccaacauaa     3300

acgacagaau aacauacgga caaguugaug guaacaaagu aaguaauaaa guaaaauuga     3360

ggccuggaaa auacuaccug uuaguauaua aauacagugg gucaggaaac uacgaacuac     3420

gaguuaacaa auaaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     3480

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3540

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     3600

cccccaaagg cucuuuucag agccaccaga auu                                  3633


<210>  7337
<211>  3357
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(111-1118) (opt13)

<400>  7337
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguaa cuuuuauaag ucuucuauuu cuauuuucau      120

cggcauauag uauagcaaac acaaacucag aaaaauauga cuuugaauau cuaaauggau      180

uaucauauac agaauuaaca aaccugauca aaaacauaaa auggaaucaa auaaacggau      240

uauuuaacua uagcacggga ucacagaaau uuuucggcga uaaaaauaga guacaagcaa      300

uuauaaaugc ucuccaagaa ucuggcagaa cguauacagc aaacgauaug aaaggaaucg      360

aaacuuuuac agaaguccug agagcagguu uuuacuuagg uuauuacaac gacgggcuaa      420

gcuaucuaaa ugauagaaac uuccaagaca aauguauacc agcaaugauu gcaauacaga      480

aaaaccccaa uuuuaaauua ggaacagcag uucaagacga aguuauaaca ucucuuggca      540

aacuuauagg gaacgcaagc gcaaacgcag aaguaguaaa caacugugua ccgguauuaa      600

aacaauucag agaaaauuua aaucaauacg caccagacua uguaaaagga acagcaguaa      660

acgaacuaau aaaaggaaua gaauuugauu ucagcggagc cgcauaugaa aaggauguca      720

aaacuaugcc gugguacgga aaaauagacc cauuuauaaa ugaacuuaaa gcacuagguu      780

uauacggaaa caucacaagc gcaacugaau gggcaucaga uguuggaauu uauuaccuau      840

cuaaauuugg acuauacuca accaacagga acgauauagu gcaaucucug gaaaaagcug      900

uagacaugua uaaauaugga aaaauagcuu ucgucgcaau ggaaagaaua acuugggauu      960

augaugguau uggaucaaac ggcaaaaagg uagaucacga uaaauucuua gaugacgcag     1020

aaaagcacua cuuaccaaaa acguauacau ucgacaacgg gacuuuuaua aucagagcag     1080

gcgauaaagu auccgaagag aaaauaaaaa gauuauacug ggcuucaagg gaaguaaaau     1140

cucaauucca ccgaguagua ggaaaugaua aagcauuaga aguggguaac gcugaugaug     1200

uauuaacaau gaaaauauuc aacagcccug aagaauacaa guucaauaca aauauaaacg     1260

gagucucuac cgauaacgga ggcuuauaca uugaaccaag aggaacauuu uacacauaug     1320

aaagaacucc acaacaaagc auauucagcc uugaggaacu auuccgacac gaauauacac     1380

auuacuuaca agccagguau cuuguagaug gacuuugggg acagggaccu uucuaugaaa     1440

agaauagacu aaccugguuc gacgaaggaa cagcagaguu cuuugcaggu ucaacaagaa     1500

caucuggagu auuaccacga aaaucaauuc ucgguuauuu agcaaaagau aaaguagauc     1560

auagauauuc acuaaagaaa accuugaacu caggauacga cgacagugac uggauguucu     1620

acaauuacgg auuugcagua gcacacuauu uauaugaaaa agauaugccu acauucauua     1680

aaaugaacaa agcaauacua aauaccgaug ugaaaagcua ugacgaaaua auaaagaaac     1740

uuucagacga ugcgaacaaa aauacagaau accaaaacca uauucaagaa cucgccgaca     1800

aauaccaagg ugcaggcauu ccucuaguaa gugacgacua uuuaaaagac cauggauaca     1860

agaaagcauc agaagucuau ucagaaauca gcaaagccgc auccuuaacu aauacaagcg     1920

ucacagcaga gaaaucacaa uacuuuaaua cauucacgcu ucgaggaacu uauacaggug     1980

aaacgucaaa aggagaguuu aaagauuggg augaaauguc aaagaaauua gauggaacac     2040

uagaaucguu agcuaaaaac ucauggucug gauauaaaac acuaaccgca uacuuuacua     2100

acuacagagu uaccagugau aacaaaguac aauacgaugu aguauuucau ggaguacuaa     2160

cagacaaugc agacauuagc aauaacaaag caccaauagc aaaaguuacc ggccccucaa     2220

caggggcagu agguagaaau auugaguucu cuggaaaaga uagcaaagau gaagauggaa     2280

aaauaguuuc auaugauugg gacuuuggug auggagcaac uagcaggggc aaaaacucag     2340

uucacgcaua caagaaagca ggaacauaua acguaaccuu aaaaguaacc gaugauaaag     2400

gagcaaccgc caccgaaagu uuuacuauag aaaucaaaaa cgaagacaca acgacaccaa     2460

uaacaaaaga aauggaacca aaugacgaca uaaaagaagc aaacggacca auaguagaag     2520

gaguaacagu aaaaggagac cuaaauggcu cggacgaugc agauacauuu uacuuugaug     2580

ucaaagagga uggugacgua accauagaac uacccuauag cggaucaagu aauuucacuu     2640

ggcuaguuua caaagaagga gaugaccaaa accauauugc aucaggaauu gauaaaaaca     2700

acucaaaagu aggcacauuc aaaucaacaa aaggacgaca uuacguuuuc auauauaaac     2760

acgacagcgc uucaaacaua ucauauucuc ucaacauaaa agguuuaggc aaugaaaaau     2820

uaaaagaaaa agaaaauaac gacucaucag auaaagcaac cguaauccca aauuucaaua     2880

caacgaugca aggaucgcuc cucggagaug acagucguga uuacuacuca uuugaaguaa     2940

aagaagaagg agaaguuaau auagaacuag auaagaaaga cgaguucgga guaacaugga     3000

cauuacaccc agagaguaau aucaacgaua gaauuacaua uggccaaguu gacggaaaua     3060

aaguuaguaa uaaaguaaaa cuuaggccag gaaaauauua ccugcucguc uacaaauacu     3120

cagguagcgg uaacuaugaa cuaagaguaa acaaauaagg acuagucccu guucccagag     3180

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3300

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3357


<210>  7338
<211>  3705
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA77453.1__HsALB(1-18)_ColG(1-110)_CS-F_ColG(111-1
       118) (opt13)

<400>  7338
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguaa cauucauuag ccucuuauuu cuauuuucau      120

cagcauacag uaugaagaaa aauauacuaa aaauauugau ggacuccuau aguaaagaga      180

gcaaaauaca aacaguaagg cgaguaacca gcgugaguuu acuugcugua uaucuaacaa      240

ugaacacaag uagccuaguu uuagcaaaac caauagaaaa uacgaaugau accuccauca      300

aaaacguaga aaaacuaaga aaugcaccaa acgaagaaaa uucaaagaaa guagaagaua      360

guaaaaacga caaaguagaa caugugaaaa acauagaaga agccaaagua gaacaaguag      420

caccagaagu caaaucuaaa uccacuuuaa gaagugcguc aaggagaaga agaaaaagaa      480

uagcaaacac aaauagugaa aaauacgauu ucgaauaccu aaacggacua uccuauacug      540

aacuaacaaa ucuaauuaaa aacauaaaau ggaaucaaau aaacgguuua uuuaacuauu      600

ccacaggcuc acaaaaauuu uucggagaua aaaaucgcgu ucaagcaaua auaaaugccc      660

uacaagaaag cgggagaacc uacaccgcaa augauaugaa aggaauagaa acauucacag      720

aaguacuuag agccgguuuc uaucuagguu acuauaacga cggauuaagu uaucuaaaug      780

auaggaacuu ccaagauaaa ugcauaccag caaugaucgc aauacagaaa aauccaaauu      840

ucaaauuggg aacagcaguc caagacgaag ugauaacauc acuaggaaaa cuaauaggca      900

acgcaagugc aaacgccgaa guaguaaaca acuguguucc aguacuaaaa caauucagag      960

aaaaccuaaa ccaauacgca ccugauuaug uuaaagguac agccgucaac gaacucauaa     1020

aagguauaga guucgacuuc ucaggagcag cguacgaaaa agauguaaaa acaaugccau     1080

gguauggaaa aauugaucca uuuauuaaug aauuaaaggc auuaggauug uacggaaaca     1140

uaaccucggc uacagaaugg gcaucagaug uaggaauaua cuaccuuuca aaauuugguc     1200

uauauagcac aaaccggaac gauauaguac aaucauuaga aaaagccgua gacauguaua     1260

aauauggaaa aauagcauuu gucgcaaugg aaagaauaac cugggacuac gacggaauag     1320

ggucuaacgg gaagaaagua gaccaugaua aauuucucga ugaugccgaa aaacauuauc     1380

uaccuaaaac uuacacuuuc gacaauggca cauucauaau cagagcuggc gacaaaguau     1440

ccgaagagaa aauaaaaaga uuauauuggg caucuagaga gguaaaaagu caguuucaca     1500

gagucguagg aaaugauaaa gcucuugagg uaggaaacgc agaugacgug uuaacaauga     1560

aaauauuuaa uucaccggaa gaauacaagu ucaauacaaa cauuaauggc guauccacag     1620

acaauggagg acuauauauc gaaccacgag gaacauucua uacauaugaa agaaccccac     1680

aacagaguau uuucagucua gaagaauuau uuaggcacga auacacccau uauuuacaag     1740

cacguuaucu aguagacgga cuaugggguc agggacccuu cuacgaaaag aaccgcuuaa     1800

caugguucga ugaagguacu gcggaauuuu ucgcuggauc aacacgaacc aguggaguac     1860

ucccaagaaa aucaauuuua gguuaccuug caaaagauaa agucgaucac agauacucac     1920

ucaaaaagac acuaaauuca ggauaugaug acucagacug gauguuuuau aauuauggau     1980

ucgcagucgc acacuaccuc uacgaaaaag auaugccaac guucauuaag augaauaagg     2040

caauacuaaa uacagaugua aaaucauacg acgaaaucau aaagaaacua uccgacgacg     2100

caaauaaaaa uacagaauac caaaaccaua uacaagaacu agcagacaaa uaucagggag     2160

caggcauccc acuuguaagc gacgacuacu ugaaagacca cggauacaag aaagcauccg     2220

aagucuacuc agaaauaucc aaagcagccu cauuaacaaa uacguccgua acugcugaga     2280

aaagucaaua uuucaacaca uucacacuac guggaacaua caccggcgaa acgaguaaag     2340

gagaguucaa agauugggac gaaaugucaa agaaauuaga cgguacacua gaaucauuag     2400

ccaaaaauuc auggagcgga uacaaaacuc uuacggcaua cuuuacaaac uauaggguua     2460

caagugauaa caaaguacaa uaugacguag uauuucaugg aguccucaca gacaaugcug     2520

auaucagcaa caacaaagcu ccuaucgcua aaguaacugg gcccaguacg ggagcaguag     2580

gcagaaacau ugaguucuca ggaaaagacu caaaagacga agauggcaaa auaguauccu     2640

augauuggga cuuuggagau ggagcaacau caagaggcaa aaacucaguc cacgcauaca     2700

agaaagcagg aacauauaau guaacacuua aaguaacaga cgauaaaggc gcaacagcaa     2760

cagaaucauu cacaauagaa auuaaaaacg aagauacaac aacaccaaua acaaaagaaa     2820

uggaaccaaa cgaugauaua aaagaggcaa acgguccaau aguggaagga guaacaguaa     2880

aaggcgacuu gaaugggagc gacgacgccg acacauuuua uuucgacguu aaagaggacg     2940

gcgacguaac aauagaauua ccauacagug gaucaagcaa cuuuacgugg cuaguuuaua     3000

aagaaggaga cgaccaaaac cauauagcaa gugguauaga caaaaacaau aguaaaguag     3060

guacauuuaa aaguaccaaa ggcagacauu acguauuuau auacaaacac gauucagcau     3120

caaacauauc auauucucua aauauaaaag gauuagggaa ugaaaaacuu aaagaaaaag     3180

agaauaauga cagcagcgac aaagcaacug ucauacccaa cuuuaacaca acaaugcaag     3240

guucacuauu aggagacgac agucgagauu auuauagcuu cgaaguaaaa gaggaaggag     3300

aagucaauau agaauuagau aagaaagacg aauuuggagu aacauggaca cuucauccug     3360

aaaguaauau aaacgauaga auaacauacg gacaaguaga cggaaacaaa gucucaaaua     3420

aaguaaaacu uagaccaggg aaauauuauc uacuuguaua uaaauacagu ggaucaggua     3480

acuaugaacu aagagucaau aaauaaggac uagucccugu ucccagagcc cacuuuuuuu     3540

ucuuuuuuug aaauaaaaua gccugucuuu cagaucuaaa aaaaaaaaaa aaaaaaaaaa     3600

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa augcaucccc cccccccccc     3660

cccccccccc cccccccaaa ggcucuuuuc agagccacca gaauu                     3705


<210>  7339
<211>  3381
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt13)

<400>  7339
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuucuuga aaauaauccu caacagagga aaaaccauga      120

aacgaaaaug ucugucaaaa agauuaaugc uagcuauaac aauggccacc auauucacag      180

ucaacucaac acuaccaauc uaugcagcag uagauaaaaa uaaugcuaca gcugcaguac      240

aaaacgaauc aaaacguuau acaguuucgu acuuaaaaac auuaaauuau uaugaccucg      300

ucgaucuauu gguaaaaaca gaaaucgaaa auuuaccaga uuuauuccaa uacagcucag      360

augcuaaaga guucuauggu aacaaaacaa gaaugagcuu cauuauggac gaaauaggua      420

gaagggcucc acaauauaca gaaauagacc auaaaggaau accaacccua guagaaguag      480

ucagagccgg auuuuaucuu ggauuccaca acaaagaauu aaaugaaauc aacaaaagau      540

cauucaaaga acgaguaauc ccaagcauau uagcaauaca aaagaaucca aauuucaaau      600

uaggaacaga aguucaggac aaaauaguua gcgcaacagg acuucuagcc ggaaaugaaa      660

cagcaccucc ugaaguagua aauaacuuua caccaauauu gcaggauugc auaaagaaca      720

uagauagaua cgcguuagau gaccuaaaau cuaaagccuu auucaaugug cuugcagccc      780

caacauacga caucacugaa uaucuccgag ccacaaaaga aaaaccagaa aacacaccau      840

gguacgggaa aauagacgga uucauaaacg aacucaagaa acuagcauua uaugguaaaa      900

uaaacgacaa caacucaugg aucauagaca augguauaua ccauauagcc ccauuaggaa      960

aacuucacag caauaauaaa auaggaauag agacauuaac agaaguaaug aaaguauacc     1020

cuuauuuaag uaugcaacau uuacaaucag cagaccaaau caaaagacau uacgacagua     1080

aagacgcgga aggaaacaaa auuccauuag acaaauuuaa aaaggaagga aaagaaaaau     1140

auuguccaaa aaccuacaca uuugacgaug gaaaagucau uauaaaagcc ggagcacgug     1200

uagaggaaga aaaagugaaa agacuuuacu gggcauccaa agaaguaaau ucacaauucu     1260

uucgaguuua cggaauugac aaaccccugg aagaaggaaa cccagacgac auuuuaacga     1320

ugguaauaua caacaguccu gaagaauaca aacuaaacag uguacuauau ggcuacgaua     1380

cgaacaacgg aggaauguac aucgaaccag aaggaacauu cuuuacguac gaaagagaag     1440

cacaggaauc aacuuauaca cuagaggaac uauuucgaca cgaauacaca cacuaucucc     1500

aagguagaua ugcaguuccg ggacaauggg gaagaacuaa guuauacgau aaugacagac     1560

uaacauggua ugaagaagga ggggccgagu uauucgcggg caguaccaga acaaguggga     1620

uauuacccag aaaaagcauu guauccaaca uacacaacac cacgaggaau aaccgauaua     1680

aacuuucaga uacaguccau ucaaaauaug gagcaucguu ugaguucuac aauuaugcau     1740

gcauguuuau ggauuauaug uauaauaaag acaugggaau acucaacaaa uuaaaugacc     1800

uagcaaagaa caaugacgug gacggauacg acaacuacau aagagaccua ucaagcaacu     1860

acgcacuaaa ugacaaauau caagaccaca ugcaagaaag aauagauaac uaugaaaauc     1920

ucacaguacc uuucguugca gaugacuacc uaguccguca ugcauacaaa aauccgaacg     1980

aaauauauuc agaaauuuca gaaguugcua aacuuaaaga ugccaaauca gaaguaaaga     2040

aaagucaaua cuucaguacu uuuacacuac gcggaagcua cacuggagga gcuucaaaag     2100

gaaaauuaga agaccaaaaa gccaugaaca aauucauaga cgauagccuc aagaaauuag     2160

auacguauag uuggucugga uauaaaacac uaacagcgua uuuuacaaau uauaaagucg     2220

auaguagcaa cagaguaaca uacgauguag uauuucaugg auauuuacca aaugaaggag     2280

auuccaaaaa uucacucccg uauggaaaaa uaaacgguac auauaaaggg acagaaaaag     2340

agaaaauaaa auucagcuca gaaggaaguu uugacccgga cgguaaaaua guaaguuacg     2400

aaugggacuu cggugacggc aauaaaucaa acgaagaaaa uccagaacac ucuuaugaua     2460

aaguaggaac cuacacagug aaauuaaaag uaacagauga uaaaggugaa ucauccguca     2520

guacgacaac agcagaaaua aaagaucugu cagaaaacaa gcucccgguu auauauaugc     2580

auguaccaaa aagcggcgcc cuaaaucaaa aaguagucuu uuacggaaaa ggaacguaug     2640

acccagacgg aaguauagca ggauaccaau gggauuuugg ggaugguagu gacuuuagca     2700

gcgaacaaaa cccaucacau gucuacacua agaaaggcga guacacaguu acacucagag     2760

uaauggacuc aaguggacaa augucagaga aaacaaugaa aauaaaaaua acagauccag     2820

uauauccaau uggaacugaa aaagaaccaa acaauucuaa agaaacagcc ucagguccca     2880

uugucccugg cauaccugua aguggaacaa uagaaaacac cagugaccaa gacuauuucu     2940

auuuugacgu uauaacaccc ggcgaaguaa aaauagacau caacaaacuu ggauacggag     3000

gagcuacaug gguuguauau gaugaaaaca auaaugcagu aaguuaugca acugaugaug     3060

gacaaaaccu aagcggaaaa uuuaaagcag auaaacccgg acgauauuau auacacuuau     3120

auauguucaa cggaaguuau augccauauc gaauaaauau agaaggaagc guaggaagau     3180

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     3240

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     3360

cuuuucagag ccaccagaau u                                               3381


<210>  7340
<211>  3342
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium histolyticum__BAA34542.1__ColH (opt13)

<400>  7340
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaagaaaau guuuaagcaa aagauuaaug cuagccauua      120

caauggcaac aauuuucaca guaaauagua cauuaccaau uuacgcagcu gucgacaaaa      180

acaacgcaac ugcagcagua cagaacgaau caaaacggua uacagugagc uaccucaaaa      240

cacuaaauua uuaugaccua guagaucuac uuguaaaaac agaaauugaa aaucuaccag      300

accuauucca auacuccuca gaugcaaagg aauuuuaugg aaacaaaacg cgcaugaguu      360

ucauuaugga cgaaauagga aggagggccc cacaguacac agaaauagau cauaaaggca      420

uaccaacgcu aguagaaguc guaagagcag gauuuuaccu agguuuucac aacaaagaac      480

ucaacgaaau aaacaagcgc aguuuuaaag aaagagucau uccaucaaua uuagcgaucc      540

agaaaaaccc uaacuucaaa cuaggaacag aaguacaaga caaaauugua ucagcgacag      600

gacuacuagc aggaaaugag acagcaccac cagaaguagu aaauaauuuc acaccaauau      660

uacaagacug caucaaaaau auagaccgau acgcauugga ugacuugaaa agcaaagcau      720

uauuuaaugu acuugcggca ccaacauaug acauaacaga auaccuaaga gcuacaaagg      780

aaaaaccaga aaacacacca ugguauggaa aaauagacgg auuuauaaau gaacugaaaa      840

aguuagcacu auacgguaaa aucaaugaca acaacagcug gauaauagac aaugggaucu      900

accauauagc cccauuaggu aaacuacauu caaacaacaa aauaggaauc gaaacccuaa      960

cagaaguaau gaaaguauau ccauaccuaa gcaugcaaca cuugcaaagc gcagaccaaa     1020

uaaaaaggca cuaugacagc aaagaugcag aaggaaacaa aauaccacuc gacaaguuca     1080

agaaagaagg uaaagaaaaa uauuguccca aaacguauac guucgaugac ggaaaaguaa     1140

ucauaaaagc aggagccaga guagaagaag aaaaaguaaa aagacuuuau ugggcuucga     1200

aagaagucaa cagccaauuc uucagaguau augguaucga caaaccucua gaagaaggaa     1260

auccagauga cauucuaaca augguaauau acaacucacc ggaggaauac aaauuaaaca     1320

guguccugua cggauacgau acaaacaacg guggcaugua uauagaacca gaagguacau     1380

ucuucacuua ugaaagagaa gcucaagaaa gcaccuacac auuagaggaa uuauuuagac     1440

augaauauac ucacuauuua caaggccgau augcaguacc aggccaaugg gggcguacaa     1500

aauuauacga uaacgauaga uuaacauggu augaagaagg uggagccgaa cuauucgcag     1560

guuccaccag gacuucagga auacuaccaa ggaaaucaau uguaaguaau auacacaaua     1620

ccacacguaa caacagauac aaauuauccg acacaguaca cucaaaauac ggagcaucau     1680

ucgaguucua caauuacgca uguauguuua uggauuauau guauaauaaa gauaugggaa     1740

uccuaaacaa acuaaaugac uuagcuaaaa auaaugacgu ugacggauac gacaauuaca     1800

uaagggacuu aaguagcaac uacgcauuaa acgacaaaua ccaagaccau augcaagaaa     1860

gaauagauaa cuaugaaaau cuaacgguac cauuuguugc agacgauuau uuagucagac     1920

augcauacaa aaacccuaau gaaauauaca gugaaauauc agaaguggca aaacuaaaag     1980

acgcuaaauc ugaaguaaag aaaagccaau acuuuaguac auucacacuu cgaggcucau     2040

acacaggagg agcaagcaag gguaaacucg aagaccaaaa agcaaugaac aaauuuauag     2100

augauucacu aaagaaauua gacacauaua guuggagcgg cuauaaaaca cuaaccgcau     2160

acuuuacuaa cuauaaagua gacucaucaa accgcguaac auacgacgua guauuucacg     2220

gauaccuccc caaugaaggu gacagcaaaa acucacuacc cuaugggaaa auaaauggga     2280

cauacaaagg uaccgaaaag gagaaaauaa aauuuucuuc ugaaggcagc uucgacccag     2340

acggaaaaau agucuccuac gaaugggacu ucggugaugg aaacaaaagc aaugaagaaa     2400

auccagaaca caguuacgac aaaguaggga cuuacacugu aaaacugaaa guuacagaug     2460

acaagggcga aagcucugua aguacaacca cugccgaaau aaaagaccua ucagaaaaca     2520

aacuuccagu aauauauaug cacguuccua aaucuggagc uuugaaccaa aaaguaguuu     2580

ucuacggaaa aggcacguau gacccggaug gaucaaucgc aggcuaucaa ugggacuuug     2640

gcgauggaag ugacuuuucc agcgaacaaa acccuagcca cgucuauacu aagaaaggag     2700

aauauaccgu gacauuacga guaauggauu caucaggaca aaugucagag aaaaccauga     2760

aaauaaaaau cacugaccca guauauccaa uaggaacaga aaaagaacca aacaacagua     2820

aagaaacagc cucaggucca auaguaccug gaauaccagu cucaggcaca auagaaaaca     2880

caucagacca agacuacuuc uauuuugaug uuauaacacc aggugaaguc aaaauagaua     2940

uaaauaaauu aggauauggu ggugcaacau gggucguaua cgaugaaaac aauaacgccg     3000

uuaguuacgc aacagacgau ggucaaaacc uaucugggaa auucaaagca gauaaaccug     3060

gaagauacua uauacaucua uauauguuua acggcagcua caugccauau agaauaaaua     3120

uagaaggguc aguaggaaga uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     3180

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     3240

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     3300

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        3342


<210>  7341
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(41-1021) (opt13)

<400>  7341
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguaa cuuuuauauc auuauuauuc cuauucaguu      120

cagcauauag uguacaaaau gaaucaaaaa gguacacagu auccuaucua aaaacguuaa      180

auuauuacga uuuaguagau cuccuaguca aaacugaaau agaaaacuua ccagaccuau      240

uccaauauuc guccgaugca aaagaauuuu auggaaauaa aacccgaaug ucauucauca      300

uggacgaaau uggacgaagg gcaccgcaau acacagaaau agaucacaaa gguauuccaa      360

cccucguaga agucguaaga gcuggcuucu accuaggauu ucauaauaaa gaauuaaaug      420

aaauaaacaa aaggucauuc aaagaaagag uaauacccuc cauauuagca auacaaaaaa      480

auccuaacuu uaaacuugga acagaaguuc aagacaaaau cguuucagcg accgguuuac      540

uggcaggcaa cgaaacagca ccucccgaag ucguaaacaa cuucacacca auuuuacaag      600

auuguauaaa aaauauugau cgauacgcuu uagacgaccu uaaaagcaaa gcgcuauuca      660

acguacucgc agcaccuaca uacgauauca ccgaauaccu ucgagcuaca aaagaaaaac      720

cagaaaauac uccuugguau ggcaaaauag acggauucau aaacgaauua aaaaaauuag      780

cuuuauaugg aaaaauuaau gauaauaacu cauggauaau agacaaugga auauaucaca      840

uugcaccauu aggaaaauua cauucuaaua auaaaauagg aauagaaaca uugacagaag      900

uaaugaaagu guaccccuac cuaagcaugc aacauuuaca gucagcugau caaauuaaac      960

gacacuacga uucaaaagac gcagaaggca auaaaauccc acuugacaaa uucaaaaaag     1020

aaggaaaaga aaaauacugu ccaaaaacau auacauuuga cgacggaaaa guaauaauaa     1080

aagcuggugc aagaguagaa gaagaaaaag ucaaaagacu auauugggca agcaaagaag     1140

uaaauucaca auucuuucga guauauggaa uugacaaacc ccuagaagag ggaaacccag     1200

acgauauacu aacaauggug auauacaacu caccagaaga auauaaacua aacaguguac     1260

uauacggaua cgauacaaac aauggcggga uguacauaga accagaaggu acauucuuca     1320

cguaugaaag ggaagcacaa gaauccaccu acacacucga agaacuauuc agacaugaau     1380

acacucauua ucuacaaggc agauaugccg uaccgggaca auggggaaga acaaaauuau     1440

augacaacga cagauuaaca ugguaugaag aaggaggagc agaacuauuu gcuggcagua     1500

ccagaacaag ugggauccuu cccagaaaau caauugugag uaacauacac aacacaacga     1560

gaaauaauag auauaaacua agcgauaccg uacauaguaa auauggagcc ucguucgaau     1620

uuuauaauua ugccuguaug uucauggauu acauguauaa caaagauaug gguauauuaa     1680

auaaauuaaa cgaccucgcu aaaaauaaug auguagacgg auacgacaac uacauaagag     1740

auuuauccag caacuaugca uuaaaugaca aauaucaaga ccacaugcaa gaaagaaucg     1800

acaacuauga aaaucuuacu guaccauucg uagcagacga uuaccuaguu agacacgccu     1860

auaaaaaucc caacgaaaua uauagcgaaa uaucugaagu agcaaagcua aaagacgcaa     1920

aaagcgaagu gaaaaaauca caauacuuuu caacuuucac auugagaggc ucauacacag     1980

gaggugcaag caaaggaaaa uuagaagauc aaaaagcaau gaauaaauuu auagacgaca     2040

gucuaaaaaa auuagauaca uacucauggu cagguuacaa aacacuaacg gcauacuuca     2100

caaacuauaa aguagauucc ucaaauagag uaacauacga ugucguuuuu cauggauauc     2160

uaccuaacga aggagacagc aagaauaguc uaccauaugg aaaaauaaau ggaacguaca     2220

aaggaacuga aaaagaaaaa aucaaauucu caucagaagg caguuucgau cccgacggga     2280

aaauaguauc auacgaaugg gauuuuggag auggcaacaa aucaaacgaa gaaaacccag     2340

aacauucaua ugauaaaguc ggaaccuaca caguaaaacu aaaaguaacc gaugacaagg     2400

gagaaucauc gguuuccacc acgacagcug aaauaaaaga cuuaucagaa aacaaauuac     2460

ccguaauaua caugcacgua ccaaaaucag gcgcgcuuaa ccaaaaagug guuuucuaug     2520

gaaaaggcac auacgaucca gauggaagca ucgcaggaua ccagugggau uucggagaug     2580

guucagauuu uaguucugaa caaaauccua gccauguaua caccaaaaaa ggugaauaca     2640

caguuacacu uaggguuaug gacuccucag gacaaaugag cgaaaaaaca augaaaauaa     2700

aaauaaccga cccaguauac ccaauaggaa ccgaaaagga accaaacaau ucuaaagaaa     2760

cagcaucagg uccaauagua ccaggaaucc cagugucagg gacaauagaa aacacaucag     2820

accaagacua uuucuauuuc gacguaauaa cacccggaga aguaaaaaua gacauaaaca     2880

aauuaggaua cgguggcgcc acuuggguug uauaugacga aaacaacaac gcaguaucuu     2940

augcaacuga cgacggccaa aacuuaagug gaaaguuuaa agccgauaaa ccuggacgau     3000

acuacauaca ccuauacaug uucaacggca guuacaugcc auacagaaua aacauagaag     3060

guagcguugg ucgauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  7342
<211>  3414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Clostridium 
       histolyticum__BAA34542.1__HsALB(1-18)_ColH(1-40)_CS-F_ColH(41-102
       1) (opt13)

<400>  7342
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauggguaa cauucaucag cuuacuauuu uuauuuucau      120

cugccuauuc caugaaaaga aaaugucuau caaaaagauu aauguuagca auaacaaugg      180

cuacaauauu cacggucaac aguacacucc caauauacgc ugcagucgac aaaaacaacg      240

cgacugcagc acgcaggcgc agaaaaagag uacagaauga aucaaaacga uacaccgugu      300

cguaccuaaa aacccuaaau uacuacgacc ucguugaccu auuaguaaaa acagaaauag      360

aaaauuuacc agaccuuuuu caauacucaa gcgaugccaa ggaauuuuac ggaaauaaaa      420

caaggaugag uuucauaaug gaugagaucg gccgccgagc accacaauau accgaaauag      480

aucauaaagg aaucccgacg uugguugaag uuguuagagc aggauucuau uuggguuuuc      540

acaacaaaga acuaaaugaa auaaauaaac gcagcuucaa agaaagagua auaccaagca      600

ucuuagcgau ucagaaaaau ccuaauuuca aacuaggaac ggaaguacaa gacaaaaucg      660

ucucagcaac gggauuguua gcgggaaacg aaaccgcucc accagaaguc guaaacaacu      720

uuacccccau acuacaagac ugcaucaaaa auauagauag auacgcauua gaugauuuaa      780

aaucuaaagc auuauucaac guauuggcgg caccaacaua ugauauaaca gaauauuuaa      840

gagcgacaaa agaaaaacca gaaaacacuc caugguaugg caaaauugac ggauuuauaa      900

augaauuaaa gaaauuggcc cuauacggaa aaauaaauga caauaacagc uggaucauug      960

acaacggaau auaccacaua gcucccuuag gaaaacuaca uaguaacaau aaaaucggua     1020

uagaaacauu aacugaagua augaaaguuu acccauaucu aaguaugcaa cauuuacaau     1080

cagcagauca aauaaaaagg cacuaugaua gcaaagacgc agagggaaac aaaauaccac     1140

uagacaaauu uaagaaagag ggaaaagaaa aauacugucc aaaaaccuac acauucgaug     1200

acggaaaagu aaucauaaaa gcaggagcaa gaguagaaga ggaaaaagua aaacgauuau     1260

auugggcauc uaaagaaguu aauucucaau ucuucagagu auacggaaua gacaaaccac     1320

uagaagaagg caauccagac gacauauuaa caaugguaau uuacaacagu ccugaagaau     1380

auaaauuaaa uucaguauua uauggauacg acacaaacaa uggaggaaug uacaucgaac     1440

ccgaaggcac auucuuuacc uacgaaagag aggcucaaga aucuacuuau acucucgaag     1500

aacuuuuuag gcaugaauau acacacuauc uccaagguag auaugccgua ccaggacaau     1560

gggguagaac aaaacuauac gauaaugaca gacuuacuug guaugaagaa ggaggcgcag     1620

aacuauuugc gggcagcaca cguacuucag gcauccuacc acgaaaaucc auaguuucca     1680

acauccacaa uacaacaaga aacaaccgau auaaauuauc agauacuguc cacucaaaau     1740

acggugcguc cuucgaauuu uacaacuacg cauguauguu uauggacuac auguauaaua     1800

aagauauggg uauacuuaac aaauugaaug acuuagccaa aaauaaugau guagacggau     1860

acgauaacua cauaagagac cuaucaucaa acuaugcauu aaaugacaaa uaucaagacc     1920

auaugcaaga aagaauugau aacuacgaaa acuuaacugu accauucgua gcagaugauu     1980

acuuaguaag acaugcauau aaaaauccaa acgaaaucua cagcgaaauc agcgaaguag     2040

ccaaacucaa agaugccaaa uccgaaguga agaaaucaca auacuucuca acauucacuu     2100

uaagagguag uuacacagga ggugcaucca aaggaaaauu agaagaccaa aaagccauga     2160

auaaauuuau agacgacagu cuaaagaaau uagauaccua cucauggagu ggauacaaaa     2220

cauuaacagc cuacuucaca aacuacaaag uagauucauc uaaccgaguc accuacgacg     2280

uaguauuuca uggcuacuua ccaaacgaag gcgauagcaa aaacucacua ccguacggca     2340

aaauuaacgg cacauacaaa ggaacagaaa aagagaaaau caaauucucc uccgaaggua     2400

gcuucgaccc agacgguaaa aucguaaguu augaauggga uuucggugac ggcaacaaau     2460

cgaacgaaga aaacccagaa cacagcuaug auaaaguagg uacauauaca gucaaacuaa     2520

aaguaaccga ugauaaaggu gaaucgucug ucucaacgac cacagccgaa auaaaagauu     2580

uguccgaaaa uaaauuacca gucaucuaua ugcauguccc aaaaucagga gcccuaaacc     2640

aaaaaguggu uuucuaugga aaaggaacau acgacccuga uggaucaaua gcaggcuauc     2700

aaugggauuu cggugacggc ucagacuuua gcagugaaca aaauccaucg cauguguaca     2760

caaagaaagg agaauacaca guaacacuac gagucaugga uucuuccgga caaaugagug     2820

agaaaacgau gaaaauuaaa auaacagacc caguauaccc aauaggaaca gaaaaagaac     2880

caaauaacuc caaagaaacc gcaucuggac caauaguccc cggaauacca guaagcggca     2940

cuaucgaaaa uacaucagac caagacuauu uuuacuuuga cguaauaacc ccaggagaag     3000

uaaaaauaga cauaaauaaa uuaggauacg gcggcgcuac auggguaguu uacgacgaaa     3060

acaacaaugc aguaucauac gcaacagaug acggacaaaa cuuaagugga aaauuuaaag     3120

cugacaaacc aggaagauau uacauacauu uauauauguu caauggaucc uauaugccau     3180

acagaaucaa cauagaagga agcguaggaa gguaaggacu agucccuguu cccagagccc     3240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     3300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     3360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           3414


<210>  7343
<211>  852
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX (opt13)

<400>  7343
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uauuauucgc augccuacua ggagcagcau      120

ucgcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaccaaucaa uacgaccccc auacccauca uacggauaug      240

aacccauggg aggauggcua caccaccaaa uaauaccagu acuaucacaa caacaucccc      300

caacacacac auuacaaccu caccaccaca uaccaguagu accagcacaa caaccaguaa      360

uaccacaaca accaaugaug ccaguaccag gacaacacuc aaugacacca auacaacacc      420

accaaccaaa ccuaccacca ccagcccaac aaccauacca accacaacca guacaaccac      480

aaccacacca accaaugcaa ccacaaccac caguacaccc aaugcaacca cuaccaccac      540

aaccaccacu accaccaaug uucccaaugc aaccacuacc accaaugcua ccagaccuaa      600

cacucgaagc auggccauca accgauaaaa caaaaagaga agaaguagac uaaggacuag      660

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      720

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      840

gccaccagaa uu                                                          852


<210>  7344
<211>  411
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-TRAP (opt13)

<400>  7344
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca ccauacccau      180

cauacggaua cgaaccaaug ggaggauggu aaggacuagu cccuguuccc agagcccacu      240

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc      360

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u               411


<210>  7345
<211>  444
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HsAMELX-LRAP (opt13)

<400>  7345
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aauaagacca ccaccaaugc      180

uaccagaccu aacacuagaa gcauggccau caacagacaa aacaaaaaga gaagaaguag      240

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      300

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      420

gcucuuuuca gagccaccag aauu                                             444


<210>  7346
<211>  483
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-60) (opt13)

<400>  7346
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa ucaauaagac      240

caccauaccc aucauacgga uacgaaccaa ugggaggaug guaaggacua gucccuguuc      300

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      420

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      480

auu                                                                    483


<210>  7347
<211>  516
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001133.1__HLA-A2-SP_HsAMELX(17-47,168-191) 
       (opt13)

<400>  7347
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa ucaauaagac      240

caccaccaau gcuaccagac cuaacacuag aagcauggcc aucaacagac aaaacaaaaa      300

gagaagaagu agacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      360

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      480

ccccccccaa aggcucuuuu cagagccacc agaauu                                516


<210>  7348
<211>  855
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY (opt13)

<400>  7348
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuagua ggagccgcau      120

ucgcaaugcc acuaccacca cauccaggac acccaggaua uauaaacuuc ucauacgaag      180

uauuaacacc acucaaaugg uaccaaucca ugauaagacc cccauacuca ucauacggau      240

acgaaccaau gggcggaugg cuacaccacc aaauaauccc aguaguaucc caacaacacc      300

cacuaacaca cacauuacaa ucacaccacc acauaccagu aguaccagca caacaaccaa      360

gaguaagaca acaagcauua augccaguac caggacaaca aucaaugaca ccaacacaac      420

accaccaacc aaaccuacca cuaccagcac aacaacccuu ccaaccucaa ccaguacaac      480

cacaaccaca ccaaccaaug caaccacaac caccaguaca accaaugcaa ccacuauuac      540

cacaaccacc acuaccaccc auguucccac uaagaccauu accaccaaua cuaccagacc      600

uacaccuaga agccuggcca gcaacagaca aaacaaaaca agaagaaguc gacuaaggac      660

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      720

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      840

agagccacca gaauu                                                       855


<210>  7349
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-TRAP (opt13)

<400>  7349
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aaugauaaga ccaccauacu      180

caucauacgg auacgaacca augggaggau gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  7350
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HsAMELY-LRAP (opt13)

<400>  7350
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaauc aaugauaaga ccaccaccaa      180

uacuaccaga ccuacaccua gaagcauggc cagcaacaga caaaacaaaa caagaagaag      240

uagacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  7351
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-61) (opt13)

<400>  7351
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac acuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauauauaaa uuucucauac gaaguacuaa caccacuaaa augguaucaa ucaaugauaa      240

gaccaccaua cucaucauac ggauacgaac caaugggagg augguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  7352
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001134.1__HLA-A2-SP_HsAMELY(17-48,169-192) 
       (opt13)

<400>  7352
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaucaa ucaaugauaa      240

gaccaccacc aauacuacca gaccuacacc uagaagcaug gccagcaaca gacaaaacaa      300

aacaagaaga aguagacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  7353
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-001-1 (opt13)

<400>  7353
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac auccaggaua cauaaacuuc ucauacgaag      180

uacucacacc auuaaaaugg uaccaaaaca ugauaagaca cccauacaca ucauacggau      240

acgaaccaau gggcggaugg cuacaccacc aaauaauacc aguaguauca caacaaaccc      300

cacaaucaca cgcauuacaa ccacaccacc auauaccaau gguaccagca caacaaccag      360

gaauaccaca acaaccaaug augccacuac caggacaaca cucaaugaca ccaacccaac      420

accaccaacc aaaccuaccc cuacccgcac aacaaccauu ccaaccacaa ccaguacaac      480

cccaaccaca ccaacccuua caaccacaau caccaaugca cccaauacaa ccacuacucc      540

cacaaccacc acuaccacca auguucucaa ugcaaucacu acuaccagac cuaccauuag      600

aagcauggcc agcaacagac aaaacaaaaa gagaagaagu agacuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  7354
<211>  414
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-TRAP (opt13)

<400>  7354
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa uaugauaaga cacccauaca      180

caucauacgg auacgaacca augggaggau gguaaggacu agucccuguu cccagagccc      240

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      300

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      360

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            414


<210>  7355
<211>  447
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__SsAMELX-LRAP (opt13)

<400>  7355
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa caugauaaga cacccaucac      180

uacuaccaga ccuaccauua gaagcauggc cagcaacaga caaaacaaaa agagaagaag      240

uagacuaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa      300

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      360

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca      420

aaggcucuuu ucagagccac cagaauu                                          447


<210>  7356
<211>  486
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-61) (opt13)

<400>  7356
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaucca ggacacccag      180

gauauauaaa uuucucauac gaaguauuaa caccacuaaa augguaucaa aauaugauaa      240

gacauccaua uacaucauac ggauacgaac caaugggagg augguaagga cuagucccug      300

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      360

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      480

agaauu                                                                 486


<210>  7357
<211>  519
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_999071.1__HLA-A2-SP_SsAMEL(17-49,167-189) 
       (opt13)

<400>  7357
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaguaaugg caccaagaac auuaguacua cuacuaucag      120

gagcacuagc acuaacacaa acaugggcaa ugccacuacc accacaccca ggacacccag      180

gauacauaaa cuucucauac gaaguacuaa caccacuaaa augguaccaa aacaugauaa      240

gacacccauc acuacuacca gaccuaccac uagaagcaug gccagcaaca gacaaaacaa      300

aaagagaaga aguagacuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      360

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      480

cccccccccc caaaggcucu uuucagagcc accagaauu                             519


<210>  7358
<211>  810
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__P45561-2__SsAMELX-001-2 (opt13)

<400>  7358
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuauua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua uauaaacuuc ucauacauaa      180

gacacccaua cacaucauac ggauacgaac caaugggagg auggcuacac caccaaauaa      240

uuccaguagu aucacaacaa acaccacaau cacacgcacu acaaccacac caccacauac      300

caaugguacc agcacaacaa ccaggaauac cacaacaacc aaugaugcca cuacccggac      360

aacacucaau gacacccaca caacaccacc aaccaaaccu accacuacca gcacaacaac      420

cauuccaacc acaaccagua caaccacaac cacaccaacc auuacaacca caaucaccaa      480

ugcacccaau acaaccacua cuaccacaac caccacuacc acccauguuc ucaaugcaau      540

cacuacuacc agaccuacca cuagaagcau ggccagcaac agacaaaaca aaaagagaag      600

aaguagacua aggacuaguc ccuguuccca gagcccacuu uuuuuucuuu uuuugaaaua      660

aaauagccug ucuuucagau cuaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaugca uccccccccc cccccccccc cccccccccc      780

ccaaaggcuc uuuucagagc caccagaauu                                       810


<210>  7359
<211>  846
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__NP_998965.1__SsAMELX-001-3 (opt13)

<400>  7359
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uauucuucgc augccuauua ggagcauccc      120

uagcaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacucacacc auuaaaaugg uaccaaaaca ugauaagaca cccauacaca ucauacggau      240

acgaaccaau gggaggcugg cuacaccacc aaauaauacc aguaguauca caacaaacac      300

cacaaucaca cgcacuacaa ccacaucacc acauaccaau gguaccagcc caacaaccag      360

gaauaccaca acaaccaaug augccacuac caggacaaca cucaaugaca ccaacacaac      420

accaccaacc aaaccuacca cuaccagcac aacaaccauu ccaaccacaa ccaguacaac      480

cacaacccca ccaaccacua caaccacaau caccaaugca cccaauccaa ccacuacuac      540

cacaaccacc acuaccacca auguucucaa ugcaaucccu acuacccgac cuaccacuag      600

aagccuggcc agcaacagac aaaacaaaaa gagaagaagu agacuaagga cuagucccug      660

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      840

agaauu                                                                 846


<210>  7360
<211>  495
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPB2__SsAMELX-002 (opt13)

<400>  7360
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuacua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

uacuaacacc acuaaaaugg uaucaaaaca ugauaagaca cccaucacua uuaccagacc      240

uaccacuaga agcauggcca gcaacagaca aaacaaaaag agaagaagua gauuaaggac      300

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      360

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      420

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      480

agagccacca gaauu                                                       495


<210>  7361
<211>  888
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GLD0__SsAMELX-003 (opt13)

<400>  7361
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacuauucgc augccuauua ggagcagcau      120

ucucaaugcc acuaccacca cacccaggac acccaggaua cauaaacuuc ucauacgaag      180

accuauacuu agaagcaaua agaauagaca gaacagcauu cguacuaaca ccacuaaaau      240

gguaccaaaa caugauaaga cacccauaca caucauacgg cuacgaacca augggaggau      300

ggcuacacca ccaaauaaua ccagucguau cccaacaaac accccaauca cacgcauuac      360

aaccacacca ccacauacca auggucccag cacaacaacc agguauaccc caacaaccaa      420

ugaugccacu accaggacaa cacucaauga caccaacaca acaccaccaa ccaaaccuac      480

cacuaccagc acaacaacca uuccaaccac aaccaguaca accacaacca caccaaccac      540

uacaaccaca aucaccaaug cacccaauac aaccacuacu accacaacca ccauuaccac      600

ccauguucuc aaugcaauca cuauuacccg accuuccacu agaagcaugg ccagcaacag      660

acaaaacaaa aagagaagaa guagacuaag gacuaguccc uguucccaga gcccacuuuu      720

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc      840

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                   888


<210>  7362
<211>  774
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__K7GPE9__SsAMELX-004 (opt13)

<400>  7362
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaacaugga uacucuucgc augccuacua ggcgcagcau      120

ucuccaugcc acuaccacca cacccaggac accccggaua cauaaacuuc ucauacgaag      180

uacucacacc acuaaaaugg uaccaaaaca ugauaagaca cccaacacca caaucacacg      240

cacuacaacc acaccaccac auaccaaugg uaccugcaca acaaccagga auaccacaac      300

aaccaaugau gccacuacca ggccaacacu ccaugacacc cacacaacac caccaaccaa      360

accuaccacu accagcccaa caaccauucc aaccacaacc cguacaacca caaccacacc      420

aaccauuaca accccaauca ccaaugcacc caauacaacc acuacuccca caaccaccac      480

uaccaccaau guucucaaug caaucacuac uaccagaccu accacuagaa gcauggccag      540

caacagacaa aacaaaaaga gaagaaguag acuaaggacu agucccuguu cccagagccc      600

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      720

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            774


<210>  7363
<211>  798
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Sus scrofa__J9JIM4__SsAMELX-201 (opt13)

<400>  7363
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccacuaccac cacacccagg acacccagga uacauaaacu      120

ucucauacga aguacuaaca ccacuaaaau gguaccaaaa caugauaaga caccccuaca      180

caucauacgg auacgaacca augggaggau ggcuacacca ccaaauaaua ccaguaguau      240

cacaacaaac accacaauca cacgcacuac aaccacacca ccacauacca augguaccag      300

cccaacaacc aggcauacca caacaaccaa ugaugccacu accaggacaa cacucaauga      360

caccaacaca acaccaccaa ccaaaccuac cacuaccagc acaacaacca uuccaaccac      420

aaccaguaca accacaacca caccaaccac uccaaccaca aucacccaug caccccauac      480

aaccauuacu accacaacca ccacucccac caauguucuc caugcaauca cuacuaccag      540

accuaccacu agaagcaugg ccagcaacag acaaaacaaa aagagaagaa guagacuaag      600

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      660

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      780

uucagagcca ccagaauu                                                    798


<210>  7364
<211>  3237
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006120.1__HsBMP1 (opt13)

<400>  7364
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagguguag cacgucuacc auuauugcua gguuuauugc      120

uacuaccccg accgggacga ccacuagacu uagccgauua cacauaugac cuagcagaag      180

aggacgauag ugaaccauua aacuacaaag auccauguaa agcugccgca uucuuaggug      240

auauagcuuu agacgaagaa gauuuacgug cauuucaagu ccagcaagca guagauuuac      300

guagacauac ugcacgcaaa aguucaauaa aagcagcugu accaggaaac acaucaacac      360

cuuccuguca aucaacaaau ggucaaccuc aaagaggggc uugcggacgu uggaggggga      420

gaaguagaag uagacgugca gcaacaaguc gaccagaacg aguauggcca gauggaguaa      480

uuccauuugu aauuggugga aacuuuacug gaucacaaag agcuguauuc aggcaagcua      540

ugagacauug ggaaaaacau acuugcguua cauucuuaga acgaacagau gaagauuccu      600

auauaguauu uacuuauaga ccuugugggu gcuguaguua uguggguaga agagggggug      660

gaccacaagc aauaucaauu gguaaaaauu gugacaaauu uggaauaguu guacaugaac      720

uaggacaugu aguaggauuu uggcacgaac auacaagacc agauagagac agacauguau      780

ccauaguuag agaaaauaua caaccaggac aagaauauaa uuuccuaaaa auggagccac      840

aggaaguaga gaguuuggga gaaacuuacg acuucgacag uauaaugcau uaugcaagaa      900

auacuuuuuc acgaggaaua uuccuagaua cuauugugcc uaaauacgaa gugaauggug      960

uaaaaccucc aauuggucaa aggacuaggu uaagcaaagg agauauagca caagcgcgca     1020

aacuuuauaa auguccagca uguggugaaa cauuacagga cucaacagga aauuuuucau     1080

caccugaaua cccuaacggg uauagugcac auaugcacug uguauggaga auaucaguaa     1140

caccaggaga gaaaauaaua uuaaacuuca cuagccugga ucuuuauaga ucgagacucu     1200

guugguauga uuauguagaa guuagagaug gcuucuggag aaaagcacca uugagagggc     1260

guuuuugugg caguaaacua ccagaaccaa uaguaucuac agauuccaga uuaugggucg     1320

aguucagaag uucauccaau uggguaggaa aagguuucuu cgccguauau gaagcgauau     1380

gcggagggga uguaaagaaa gacuaugguc auauacaaag cccuaauuau ccugaugacu     1440

auaggccaag uaaaguuugu auuuggagaa uacaaguguc agaagguuuu cacguuggac     1500

ucacauuuca aucuuuugaa auagagcgcc augacucaug ugcguaugac uauuuagagg     1560

uaagagacgg acauucagaa ucuucuacuc uuauaggaag auauugugga uaugagaaac     1620

cagaugauau aaaaaguaca aguucucgac uaugguuaaa auuuguaagc gauggaagca     1680

uaaauaaagc aggauuugca guaaauuucu uuaaagaagu ugaugaaugc ucgagaccua     1740

auagaggggg augcgaacaa cgaugucuaa auacacucgg aagcuacaaa uguagcugug     1800

auccaggaua ugaacuugca ccggacaaaa gaagauguga agcugcaugc ggcggauuuc     1860

uaaccaaacu caauggauca auuacuuccc caggauggcc uaaagaauau ccaccgaaua     1920

aaaacugcau auggcaauua guagcuccaa cacaauaucg caucagcuua caauuugacu     1980

ucuuugaaac ugagggaaau gauguuugua aauaugacuu ugucgaaguc agaucaggcc     2040

ucacagcaga uucuaaauua cacggcaaau uuuguggaag cgaaaaaccg gaaguaauaa     2100

caucacaaua caauaacaug agaguagagu uuaaaagcga uaauacagua aguaagaaag     2160

gauuuaaagc acacuucuuc ucagauaaag acgaauguuc aaaagacaau gggggauguc     2220

aacaagacug uguaaauacg uuuggaucau augaauguca augccgaagu ggauucguac     2280

uucaugauaa uaaacaugau uguaaagaag cagguugcga ucacaaaguu acaucaacuu     2340

caggcacaau aacuucaccu aacuggccag auaaauaucc aucaaagaaa gaauguacau     2400

gggcaauauc uucaacccca ggucaucgcg uaaaauuaac auuuauggaa auggauauug     2460

aaucacaacc agaaugugca uaugaucacu uagaaguauu cgacggaagg gaugcaaaag     2520

caccaguauu agguagauuu uguggcagua agaaaccaga accaguucuu gcgacaggaa     2580

gccguauguu uuuaagauuu uacucagaua auuccguaca aagaaaagga uuucaagccu     2640

cccaugcgac ggaaugugga ggacaaguac gagcagaugu uaaaaccaaa gaccuauacu     2700

cacacgcaca auuuggugau aauaauuacc cagguggggu agacugcgaa uggguaauag     2760

uagcagaaga aggguacgga guugaauuag uauuccaaac auuugaagua gaagaagaaa     2820

ccgauugugg cuaugauuau auggaacuau ucgacggaua cgacuccaca gcaccgagau     2880

uaggacgaua cuguggaagu ggaccaccag aagaaguuua uucagcagga gacucagucu     2940

uagugaaauu ucauucggac gacacaauaa ccaagaaagg auuccacuua agauacacuu     3000

caacuaaauu ccaagauaca cuacacagua gaaaauaagg acuagucccu guucccagag     3060

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     3120

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     3180

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        3237


<210>  7365
<211>  1467
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001191.1__HsBMP2 (opt13)

<400>  7365
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucgccggaa ccagaugccu auuagcccua cuauuaccac      120

aaguucuacu agguggagcu gcaggauuag uaccagaacu aggaagacga aaauucgcgg      180

cagcauccuc aggaagacca ucaucacagc caucagacga aguacuaucc gaauucgaac      240

uaagguuauu aucuauguuu ggauuaaaac aaagaccaac gccaucuaga gacgcagucg      300

uuccaccaua caugcuagau cuauauagaa gacacuccgg acaaccagga uccccagcac      360

ccgaucauag auuagaacga gccgcaucac gugcaaacac cguaagaucc uuccaccacg      420

aagaaucucu agaagaacua ccagaaacau caggaaaaac uacaagaaga uucuucuuua      480

accuaucauc uaucccaaca gaagaauuca ucacaucagc agaauuacaa gucuuuagag      540

aacaaaugca agacgcauua ggaaauaacu caucauuuca ccacagaauu aacauauacg      600

aaauaaucaa accagcaacc gcaaacagca aauucccagu cacucgauua cuagauacaa      660

gacuaguuaa ccaaaacgca ucaagauggg aaucauuuga cguaacuccc gcaguuauga      720

gauggacagc acaaggacac gcaaaucacg gauuugucgu ugaaguagcc cauuuagaag      780

aaaaacaagg aguuucaaaa agacacgucc gcauaagcag aucacuacau caagacgaac      840

auucuuggag ucaaauaaga ccacuacuug uaacauucgg ccacgacgga aaaggacacc      900

cauuacacaa aagagaaaaa agacaagcaa aacacaaaca aagaaaaaga cuaaaaucau      960

caugcaaaag acauccauua uacguagauu ucucagaugu aggauggaac gacuggauag     1020

uagcaccacc aggauaccac gcauuuuacu gccauggaga augcccauuu ccacuagcag     1080

accaccucaa cucaaccaac cacgcaauag uucaaacccu aguaaauuca guaaauucaa     1140

aaauaccaaa agcaugcugu gucccaacag aacuuucugc aauaucaaug cuauauuuag     1200

augaaaacga aaaaguaguu cuaaaaaauu accaagacau ggucguagaa ggaugcggau     1260

guagauaagg acuagucccu guucccagag cccacuuuuu uuucuuuuuu ugaaauaaaa     1320

uagccugucu uucagaucua aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaugcaucc cccccccccc cccccccccc ccccccccca     1440

aaggcucuuu ucagagccac cagaauu                                         1467


<210>  7366
<211>  1503
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001193.2__HsBMP4 (opt13)

<400>  7366
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug auaccaggaa auagaaugcu caugguagua uuauuaugcc      120

aaguacuucu agguggagcu ucacaugcau cacuuauacc agaaaccgga aaaaaaaaag      180

uagcagaaau acaaggacau gccggaggaa gaagauccgg acaaucacau gaauuacuac      240

gagauuuuga ggccacuuua uuacagaugu ucggauuaag aagacgaccu caaccaucaa      300

aaucagcagu aauuccagac uacaugcgag aucuauacag auuacaauca ggagaagaag      360

aagaagaaca aauacacagu accggacuag aauacccaga aagaccagca ucaagagcca      420

auaccguuag aucauuccac caugaagaac auuuagaaaa uauaccagga acaucagaaa      480

auucagcuuu cagauuuuua uucaauuuaa gcagcauacc agaaaacgaa gucauaucau      540

cagcagaacu aagacuauuu agagaacaag uugaccaagg accugacugg gaacgcggau      600

uccacagaau aaauauauac gaaguaauga aaccaccugc ugaaguagua ccaggacacc      660

uaauaacuag auuacuagau acaagacuag uacaccauaa uguaacaagg ugggaaacau      720

uugacguauc accggcagua uuacggugga caagagaaaa acaaccaaau uacggacuag      780

caauagaagu cacacacuua caucaaacaa gaacacauca gggucaacac guaagaauau      840

cacgaucacu uccacaaggu ucagguaacu gggcccaauu aagaccauua cuaguaacau      900

uuggacauga cggaagagga cacgccuuaa cacgaaggcg aagagccaaa agaaguccaa      960

aacaccauuc acaaagagca cgaaaaaaaa acaaaaauug ccgaagacau ucacuauacg     1020

uagacuuuuc agaugucgga uggaaugacu ggaucguagc accaccaggc uaccaagcau     1080

uuuacuguca cggagauugc ccauuuccac uagcagauca cuuaaacuca accaaucacg     1140

caauaguaca aacacuagua aauucuguaa acagcucuau accaaaagcu uguuguguac     1200

caacagaacu aucagccaua ucuauguuau aucuagauga auaugauaaa guaguauuaa     1260

aaaacuauca agaaaugguc guagaaggau gcggauguag auaaggacua gucccuguuc     1320

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1440

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1500

auu                                                                   1503


<210>  7367
<211>  1818
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001709.1__HsBMP6 (opt13)

<400>  7367
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cccggauuag gaagacgagc acaauggcua ugcugguggu      120

gggguuuauu auguagcugu ugcgguccac caccuuuaag accaccauua ccagccgcag      180

cugcugcugc agcaggcggu caacuauuag gagauggggg aucacccggg agaacagaac      240

aacccccacc aucaccccaa agcucaucag gguucuuaua cagaagauua aaaacacaag      300

aaaaacgcga aaugcaaaaa gaaauacuaa guguauuagg auugccacau agaccuagac      360

cauuacaugg auuacaacaa ccacaaccuc cagcuuuaag acaacaagaa gaacaacaac      420

aacaacaaca auuacccaga ggagaaccac ccccaggaag acuaaaaucu gcuccauuau      480

ucaugcuaga ccuauacaau gcacuaagcg cagacaauga cgaagaugga gcuucugaag      540

gagaaagaca acaaucaugg ccucaugaag cagcuucaag cagucaaagg agacaaccac      600

caccaggagc agcacaccca cuuaaucgaa aaagccuacu agcacccggc ucuggaucag      660

gaggcgcaag uccauuaaca ucagcacaag auagcgcguu uuuaaaugac gcagacaugg      720

uaaugucauu cgugaauuua guagaauacg auaaagaauu uucuccaaga caaagacacc      780

acaaagaguu caaauucaau cuaucccaaa uaccugaagg agaaguagua acugcagcag      840

aauuuagaau cuacaaagac uguguaaugg gaucauucaa aaaucaaacu uucuuaauau      900

cuaucuacca aguauuacaa gaacaucaac auagagacuc ugauuuauuc cucuuagaca      960

caagaguugu augggcauca gaagaagguu ggcuagaauu ugacauuacu gcaacaucaa     1020

acuuaugggu aguaacacca caacauaaca ugggacuaca auuaucaguc guaaccagag     1080

augguguuca uguacacccu agagcugcag gacuuguagg cagagacgga ccauacgaua     1140

aacaaccauu caugguagca uucuucaaag uaucagaagu acauguaaga acaacacgau     1200

cugcuagcuc aagaagaaga caacaaaguc gcaacagauc uacacaauca caagauguag     1260

cacgaguauc aucugcuuca gacuauaacu ccuccgaacu aaaaacagca ugcaggaaac     1320

acgaauuaua cguuuccuuc caagauuuag gauggcaaga cuggauaaua gcacccaaag     1380

gauacgcugc aaacuacugc gacggugaau guucauuucc auuaaaugca cauaugaacg     1440

caacaaacca ugcaaucgua caaacucuag uacaccuaau gaauccagaa uaugucccca     1500

aaccauguug cgcacccaca aaacuuaacg caauaucagu cuuauacuuu gacgacaauu     1560

caaauguaau ccuaaagaaa uauagaaaca ugguagucag agccugcggu ugccauuaag     1620

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc     1680

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu     1800

uucagagcca ccagaauu                                                   1818


<210>  7368
<211>  1572
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001710.1__HsBMP7 (opt13)

<400>  7368
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cauguaagau cacuaagagc agcugcccca cacucauuug      120

uagcacugug ggcaccacuu uuuuuacuaa gaagcgcauu agcagacuuu ucacuagaca      180

augaaguaca uucaagcuuu auucauagga gacuucgguc acaagaaaga cgugaaaugc      240

aaagagaaau auuaucuauu cuaggacuac cacaccgccc aagaccacau cuacaaggaa      300

aacacaauuc agcuccaaug uucaugcuag aucuuuauaa cgcaauggca gucgaagaag      360

gaggaggccc cggaggacaa ggauuuuccu auccauauaa agcaguauuu ucaacacaag      420

gaccuccucu agcaagucua caagauucac auuucuuaac agaugcagau augguaaugu      480

cauuuguaaa uuuaguagaa caugauaaag aauuuuuuca cccacguuac caccauagag      540

aauucagauu cgaucuaucu aaaauaccag aaggugaagc aguaacagca gcugaauuca      600

gaauauacaa agauuacaua cgagaaagau uugacaacga aacauucaga auaucaguau      660

aucaaguacu acaagaacac uuagguagag aaagcgaucu auuucuauua gacuccagaa      720

cacucugggc aucagaagaa ggcuggcuag uauucgauau aacagcaacc aguaaucacu      780

gggucguaaa cccaagacac aaccucggac uacaauuauc aguagaaaca uuagacggcc      840

aaaguauuaa cccaaaacuc gcaggacuaa uaggaagaca cggaccacaa aacaaacaac      900

cauucauggu agcauucuuu aaagcaaccg aaguacacuu cagaucaaua cgaucaacag      960

gauccaaaca aagaagccaa aauagaucaa aaacuccaaa aaaucaagaa gcauuaagaa     1020

uggcaaaugu agcugaaaau ucaucaagug aucaaagaca agccugcaaa aaacacgaau     1080

uauacguauc cuuccgagau uuaggauggc aagacuggau aauagcaccu gaaggcuacg     1140

ccgcauacua cugugaagga gaaugugcau uucccuuaaa cucauauaug aacgcaacua     1200

aucacgcuau aguacaaaca cuaguacacu uuauaaaucc cgaaacagua cccaaaccau     1260

gcugcgcacc aacacaacuc aacgcuauau caguauuaua uuuugacgac ucuucuaacg     1320

uuauccuaaa aaaauaucga aauaugguag ucagagcaug uggcugccac ugaggacuag     1380

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1440

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1500

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1560

gccaccagaa uu                                                         1572


<210>  7369
<211>  576
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006264.2__HsCCL7 (opt13)

<400>  7369
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaagcaucag cagcacuacu augccuacua cuaacagcag      120

cagcauucuc accacaagga cuagcacaac caguaggaau aaacacauca acaacaugcu      180

gcuacagauu cauaaacaaa aaaauaccaa aacaaagacu agaaucauac agaagaacaa      240

caucaucaca cugcccaaga gaagcaguaa uauucaaaac aaaacuagac aaagaaauau      300

gcgcagaccc aacacaaaaa uggguacaag acuucaugaa acaccuagac aaaaaaacac      360

aaacaccaaa acuauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu      420

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      480

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc      540

ccccccccaa aggcucuuuu cagagccacc agaauu                                576


<210>  7370
<211>  3900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001954.2__HsEGF (opt13)

<400>  7370
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uugcuuacuu uaauaauauu acuuccaguu gucaguaaau      120

uuucguuugu gucauuaucu gcaccacaac auuggaguug uccagaaggu acgcuagcag      180

gcaacgguaa uucuacgugu gucgguccag cgccauuucu aaucuuuucu caugguaacu      240

ccauuuuuag aauagauaca gaagguacaa auuacgaaca auuaguaguu gacgcaggag      300

ucagcguaau aauggacuuu cauuauaaug agaaaagaau cuauugggua gacuuggaaa      360

gacaauuacu ucagcgugua uucuugaaug gauccagaca agaaagagua uguaauauag      420

agaaaaaugu aucagguaug gcuauaaacu ggauaaauga agaagugauu uggucaaauc      480

aacaagaagg gaucauuacc guuacagaca ugaaaggaaa uaauucccac auacuacuau      540

cagcacuaaa auaucccgcc aauguugcag uagauccagu ggaaagauuu auauuuuggu      600

ccucagaagu agcaggauca uuauauagag cagacuuaga cggugugggu guuaaggcuu      660

uacuagaaac uucugagaaa auuaccgcag uaaguuuaga cguuuuagac aaaagauuau      720

uuuggauuca auauaauagg gaagguucaa auucacuuau auguucuugc gacuaugaug      780

guggaucagu gcauauaagu aaacauccaa cgcaacacaa ucucuuugca augucuuuau      840

uuggugauag aauauuuuac agcacuugga aaaugaaaac aauauggaua gccaacaaac      900

auaccggaaa agauauggua aggauaaauc uacacaguuc cuucguuccu uuaggugaac      960

uaaaaguagu acauccacua gcgcaaccua aagcggaaga ugacacuugg gaaccagaac     1020

aaaaacuaug uaaguuacga aaaggcaacu guucaucuac agugugcggg caagacuuac     1080

aaagucacuu auguaugugc gcggaaggcu augcgcucag uagagauaga aaauauugug     1140

aagauguaaa ugaaugugca uuuuggaacc auggauguac acuaggaugc aaaaauacac     1200

cagguucaua uuauuguacu ugucccguug gauuuguccu guuaccagac ggcaaaaggu     1260

gccaucagcu aguaaguugu ccacguaaug uuucagaaug uagccacgau uguguuuuga     1320

caagugaagg accacuaugc uuuugcccag aaggaucagu auuagaaagg gauggaaaaa     1380

cauguagugg uuguaguuca ccagauaaug gagguuguag ucaacuuugu guuccauuau     1440

cuccuguauc uugggaaugc gauuguuucc cagguuauga uuuacaauua gaugagaaaa     1500

guugugcagc gucuggccca caaccauucu uacucuuugc aaauucacaa gauauaagac     1560

acaugcauuu cgauggcacc gacuacggca cccuauuaag ucaacaaaug gggaugguau     1620

augcacuuga ccaugaucca guagaaaaca aaauauacuu cgcacauacc gcacucaaau     1680

ggaucgaaag agcaaauaug gacggaaguc aaagggaacg guugauugaa gaaggaguag     1740

auguaccuga ggguuuagca guugauugga uagggaggag auuuuauugg acggacaggg     1800

ggaaaaguuu aauaggacga agcgaccuca acgggaaaag aagcaaaaua aucacuaaag     1860

aaaauauuuc acaaccaaga ggaauugcug uacauccaau ggcaaaacgu cuauuuugga     1920

cagacacagg aauaaauccu agaauagagu ccaguucacu gcaaggauug gggagauuag     1980

ugaucgccag uuccgaccua auauggccau cgggaauuac aauagacuuu uuaaccgaua     2040

aacuauauug gugcgaugca aaacagucag uaauugaaau ggccaaucua gauggaucua     2100

aaagaagaag acuaacacaa aaugaugugg gacacccauu ugcuguugcc guuuucgagg     2160

acuacgucug guuuucagau ugggcaaugc caagugucau gagagucaau aagagaacug     2220

guaaggauag agucagauua caaggcucaa uguuaaaacc aucgagucua gucguagucc     2280

acccauuagc aaaaccaggu gcagaucccu gcuuauauca aaauggaggg ugcgaacaca     2340

uauguaagaa aagacuuggc acagcauggu guucauguag agaaggauuu augaaggcuu     2400

cagauggaaa aaccuguuua gcauuagaug gccaucaacu ucucgccgga ggagaaguug     2460

acuugaaaaa ccaaguaaca ccccuagaua uauuaagcaa aacaagaguu agcgaagaua     2520

acauaacaga aucucaacau auguuaguag cagaaauuau ggucucagau caagaugacu     2580

gcgcaccugu aggauguucu auguaugcua gaugcauauc agagggggaa gaugcgacau     2640

gucaaugcuu aaaaggauuu gcaggcgacg gaaaauuaug cucagacaua gacgaaugug     2700

aaaugggagu uccuguuugu ccuccagcau cuuccaaaug uauaaauacc gaaggugguu     2760

auguauguag auguagugaa ggauaccaag gggacgguau ccauuguuua gauauagaug     2820

aaugccaauu gggagaacac uccuguggag agaacgcauc cuguacaaau acugaaggag     2880

guuauacgug uaugugcgca ggaaggcuuu ccgaaccugg uuuaauuugc ccagauucaa     2940

caccuccccc acaccuucgu gaagaugacc accauuauag uguacgaaau ucagauucug     3000

agugcccacu aagccaugau ggauauuguu uacacgaugg aguaugcaug uacauagaag     3060

cguuggauaa auacgcuugu aauugugugg uuggauacau aggugaaaga ugucaauacc     3120

gagaccuaaa auggugggaa cuaagacaug ccgggcacgg acaacaacaa aaaguaauag     3180

ucguugcagu guguguagua gucuuaguca ugcuauuacu auugagccuc uggggugcac     3240

acuauuauag gacacaaaaa cuacuaucua aaaaccccaa aaauccauau gaagaaucaa     3300

gucgugaugu cagaucaaga agaccagcag acacagaaga cggaauguca ucguguccac     3360

aaccaugguu ugugguaauu aaagaacauc aagaucucaa aaacggaggc caacccguug     3420

cuggugaaga uggacaagca gcagauggua guaugcagcc cacaucaugg cgacaagagc     3480

cacaauuaug cggcauggga acagaacaag guuguuggau uccaguuagu ucugacaaag     3540

gaagcugucc gcaagugaug gagaggucau uucauaugcc aagcuacgga acacagacac     3600

ucgaaggcgg aguagagaaa ccacauucgc uucuuucugc aaacccauua uggcaacaaa     3660

gagcucuaga uccaccucac caaauggaau ugacucaaua aggacuaguc ccuguuccca     3720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     3780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     3840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     3900


<210>  7371
<211>  786
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001423.1__HsEREG (opt13)

<400>  7371
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagcaggca gaagaaugga aaugcuaugu gcaggacgag      120

uaccagcauu auuacuaugu cuaggauucc auuuauuaca agcaguacua agcacaacag      180

uaauaccaag cuguauacca ggagaaagcu cagacaauug cacagccuua guacaaacag      240

aagacaaucc aagaguagca caaguaagua uaacaaaaug cucaagcgau augaauggau      300

auugcuuaca cggacaaugu auauaucuag uagacaugag ccaaaacuau ugcagaugcg      360

aagucggaua cacaggagua agaugugaac auuucuucuu aacaguacau caaccacuau      420

caaaagaaua cguagcauua acaguaauau uaauaauacu auuucuaaua acaguaguag      480

gaagcacaua cuauuucugu agaugguaca gaaacagaaa aucgaaagaa ccaaaaaaag      540

aauacgaacg aguaacauca ggagauccag aacuaccaca aguauaagga cuagucccug      600

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc      780

agaauu                                                                 786


<210>  7372
<211>  744
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000791.1__HsFGF1 (opt13)

<400>  7372
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagaaggag aaauaacaac auucacagca cuaacagaaa      120

aauucaaccu accaccagga aacuacaaaa aaccaaaacu acuauacugc ucaaacggag      180

gacacuuccu aagaauacua ccagacggca caguagacgg aacaagagac agauccgacc      240

aacacauaca acuacaacua ucagcagaau caguaggaga aguauacaua aaaucaacag      300

aaacaggaca auaccuagca auggacacag acggacuacu auacggauca caaacaccaa      360

acgaagaaug ccuauuccua gaaagacuag aagaaaacca cuacaacaca uacauaucaa      420

aaaaacacgc agaaaaaaac ugguucguag gacuaaaaaa aaacggaagc ugcaaaagag      480

gaccaagaac acacuacgga caaaaagcca uacuauuccu accacuacca guaucaucag      540

acuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag      600

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag      720

gcucuuuuca gagccaccag aauu                                             744


<210>  7373
<211>  1143
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001997.5__HsFGF2 (opt13)

<400>  7373
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaggaguag gagggggaga uguagaagau guaacaccaa      120

gaccaggugg augucaaauu agcggaagag gugcaagagg auguaaugga auaccaggag      180

cagcagcuug ggaagcagca uuaccgagaa gacgaccgag aagacauccg agugugaauc      240

caagaucaag agcagcugga agcccaagaa caagaggaag aagaacagaa gaaagaccaa      300

guggaagcag auuaggagau agaggaagag gacgagcauu accaggagga agauuaggag      360

gaagaggaag aggaagagca ccagagagag uaggagggag aggaagagga agaggaacag      420

cagcgccaag agcagcacca gcagcaagag gaucaagacc aggaccagca ggaacaaugg      480

cagcgggaag uauaacaaca uuaccagcuc uaccagaaga uggaggaagu ggggcguuuc      540

caccaggaca uuuuaaagau ccaaaaagau uauauuguaa aaauggagga uuuuuuuuaa      600

gaauacaucc agauggaaga guagaugggg uaagagaaaa aucagaucca cauauaaaau      660

uacaauuaca agcggaagaa agaggagugg uaaguauuaa aggaguuugu gcaaauagau      720

auuuggcgau gaaagaagau gggagguuau uagcaaguaa auguguaacg gaugaauguu      780

uuuuuuuuga aagacuagaa agcaauaacu auaacacaua uagaucgaga aaauacacau      840

caugguaugu agcauuaaaa agaacaggac aauauaaacu aggaaguaaa acaggaccag      900

gacaaaaagc aauauuauuu uuaccaauga gugcaaagag uuaaggacua gucccuguuc      960

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     1020

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     1080

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     1140

auu                                                                   1143


<210>  7374
<211>  861
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002000.1__HsFGF7 (opt13)

<400>  7374
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacaaaugga uacuaacaug gauacuacca acacuacuau      120

acagaagcug cuuccacaua auaugccuag uaggaacaau aucacuagca ugcaacgaca      180

ugacaccaga acaaauggca acaaacguaa acugcucauc uccagaaaga cacacaagau      240

cauacgacua cauggaagga ggagacauaa gaguaagaag acuauucugc agaacacaau      300

gguaccuaag aauagacaaa agaggaaaag uaaaaggaac acaagaaaug aaaaacaacu      360

acaacauaau ggaaauaaga acaguagcag uaggaauagu agcaaucaaa ggaguagaau      420

cagaauucua ccuagcaaug aacaaagaag gcaaacuaua cgcaaaaaaa gaaugcaacg      480

aagacugcaa cuucaaagaa cuaauacuag aaaaccacua caacacauau gcaagcgcaa      540

aauggacaca caacggagga gaaauguucg uagcauuaaa ccaaaaagga auaccaguaa      600

gaggaaaaaa aacaaaaaaa gaacaaaaaa cagcacacuu ccuaccaaug gcaauaacau      660

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu      720

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      780

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu      840

cuuuucagag ccaccagaau u                                                861


<210>  7375
<211>  903
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001936.1__HsHBEGF (opt13)

<400>  7375
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauuauuac caucaguagu acuaaaacua uuucuagcag      120

caguacuauc agcauuagua acaggagaaa gccuagaaag acuaagaaga ggacuagcag      180

caggaaccuc aaacccagac ccaccaacag uaucaacaga ucaauuacua ccacuaggcg      240

gaggaagaga uagaaaagua agagacuuac aagaagcaga ccuagauuua cuaagaguaa      300

cauuaucauc aaaaccacaa gcacuagcaa caccaaacaa agaagaacac ggaaaaagaa      360

aaaaaaaagg aaaaggauua ggaaaaaaac gagauccaug ccuaagaaaa uauaaagacu      420

ucugcauaca uggagaaugc aaauacguca aagaacucag agcaccaagc ugcauauguc      480

acccuggaua ccacggagaa agaugccacg gacuaagucu uccaguagaa aacagauuau      540

acacauacga ccacacaaca auacuagcag uaguagcagu aguauuaagc ucaguauguc      600

uauuaguaau aguaggucua cuaauguuca gauaucaccg aagaggagga uacgauguag      660

aaaaugaaga aaaaguaaaa cuaggaauga caaauagcca cuaaggacua gucccuguuc      720

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau      840

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga      900

auu                                                                    903


<210>  7376
<211>  2463
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000592.3__HsHGF (opt13)

<400>  7376
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uggguaacua aacuauuacc agcauuacua uuacaacaug      120

uccuacuaca ccuacuauua cuaccuauug caauaccaua cgccgaaggu caaagaaaac      180

gaagaaauac aauacaugag uucaaaaagu cagcaaaaac aacauuaauc aaaauagacc      240

cagcacuaaa aauaaaaaca aagaaaguaa auacagcaga ucaaugugca aacagaugca      300

cuagaaacaa aggacuacca uuuacaugua aagcauucgu auuugauaaa gcaagaaaac      360

aaugucuaug guuuccauuu aauagcauga guucaggagu aaagaaagag uucggacaug      420

aauuugaccu auaugaaaau aaagacuaua uaagaaauug cauaauaggu aaaggaagau      480

cauauaaagg aacaguuucc aucacaaaau caggaauaaa augucaaccc uggucaucaa      540

ugauaccaca cgaacauagc uuucuaccaa gcucauacag agguaaagau cuacaagaaa      600

auuauuguag aaauccgaga ggugaagaag gcggaccaug guguuuuacu ucuaauccag      660

aaguacgaua ugaaguaugu gauauaccgc aaugcucaga aguagaaugu augacaugua      720

acggagaauc auauagaggu uugauggauc auacagaauc aggcaaaaua ugucaaaggu      780

gggaccacca aacuccacau cgacauaaau uucuaccaga acguuaucca gauaaaggcu      840

uugaugauaa uuacugucga aacccagacg gacaaccaag accuuggugc uacacauuag      900

auccccauac ucgaugggaa uacugugcaa uaaaaacaug cgcagauaac acaaugaaug      960

acacagaugu uccucuagaa acuacugaau gcauacaagg acaaggagaa ggauaccgag     1020

gaacuguaaa uacaauaugg aauggaauac cuugucaaag augggauuca caauauccuc     1080

augaacauga caugacccca gaaaauuuua aaugcaaaga ucuaagagaa aauuauugca     1140

gaaacccaga cggaucugaa ucgccauggu guuuuacaac ugauccuaac auaagaguag     1200

gcuauugcuc ucagauaccg aauugcgaca ugagccaugg acaagacugu uauagaggaa     1260

auggcaaaaa uuacauggga aaucucaguc aaacaagauc aggauuaacu uguucaaugu     1320

gggacaaaaa uauggaagau uuacauagac acauauucug ggaaccagac gcaucaaaau     1380

uaaaugaaaa cuauugcaga aauccagaug acgacgcaca cgggccaugg uguuauacag     1440

gaaauccauu aauaccaugg gacuacuguc cuauaagccg augugaagga gauacaacuc     1500

ccacaauugu aaacuuagau cauccaguaa ucucaugugc caaaacaaaa caauuaagag     1560

ucguaaacgg uauaccuacu aggacaaaca uaggcuggau ggugucacuu agauauagaa     1620

auaaacacau augcggaggc agucuuauaa aagaaucaug gguccucaca gcaagacaau     1680

guuuucccag cagagauuua aaggacuaug aagcaugguu aggaauacac gauguacacg     1740

gacgaggaga cgaaaaaugu aaacaaguac uaaauguuuc ucagcuaguc uauggaccag     1800

aagggagcga uuuagucuua augaaacuag caagaccggc agucuuagac gacuucguau     1860

cuacaauuga uuuaccuaac uacggaugca cgauaccaga aaagacuagc uguucuguuu     1920

auggaugggg uuauacugga cuaaucaacu acgacggacu auuaagggug gcacauuuau     1980

auauuauggg aaacgaaaaa uguucucaac accacagagg aaaaguaaca uuaaacgaau     2040

cagaaauaug cgcaggagca gagaaaaucg gaucaggccc gugugaagga gacuauggug     2100

ggccgcuagu gugcgaacaa cacaaaaugc gaaugguauu agggguaaua guaccuggac     2160

ggggaugcgc cauaccaaau agaccaggaa uauucguaag aguagcauau uaugccaaau     2220

ggauacauaa aauaauacua acauauaaag uaccacaauc uuaaggacua gucccuguuc     2280

ccagagccca cuuuuuuuuc uuuuuuugaa auaaaauagc cugucuuuca gaucuaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaau     2400

gcaucccccc cccccccccc cccccccccc cccccaaagg cucuuuucag agccaccaga     2460

auu                                                                   2463


<210>  7377
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005336.3 __HsHSPA1A (opt13)

<400>  7377
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gccaaagcag cugcaauagg aauagaucua ggaacaacau      120

acuccugugu aggaguauuc caacacggaa aaguagaaau aaucgcaaau gaucaaggua      180

acagaacaac accaucauac guugcauuua cagacacaga aagauuaaua ggagaugcag      240

ccaaaaacca agucgcacua aauccacaaa acacaguauu ugaugcaaaa cgcuuaauag      300

gaagaaaauu uggcgaucca guaguacaau cagacaugaa acauuggcca uuucagguaa      360

uaaacgaugg agauaaacca aaaguucaag uuaguuacaa aggcgaaacu aaagcauuuu      420

acccggaaga gauaucaagc augguauuaa caaaaaugaa agaaaucgca gaggcuuauu      480

uaggauaccc aguaacaaac gcaguaauaa caguaccagc uuacuuuaau gauagucaga      540

gacaagcaac uaaagaugcc ggaguaauug ccggacuaaa cguacuaaga auaauaaacg      600

aaccaacugc agcagcaaua gcauauggau uagauagaac aggcaaagga gaaagaaaug      660

uauuaauauu cgaccuagga ggagguacau ucgacguguc aauauuaaca auugaugaug      720

gaauauucga aguaaaagca acagccgggg acacacauuu agggggagaa gauuuugaca      780

acagacuggu aaaccauuuu guagaagaau uuaaaagaaa acacaagaaa gacauuucac      840

aaaauaaaag ggcaguuaga agacuaagaa cugcauguga gagggcaaaa aggacguuaa      900

gcaguaguac ccaagcauca cuagagauag acucauuauu ugaaggaauu gauuuuuaua      960

cuucaaucac gagagcgaga uuugaagaau uauguaguga ucucuuuaga ucgacauuag     1020

aaccugucga aaaagcacua agagaugcga aacuagacaa agcacaaaua caugacuuag     1080

uucuaguagg aggaucaacc agaauaccaa aaguacaaaa acuacuacaa gauuucuuca     1140

acggaaggga cuuaaauaaa ucaauaaacc cagaugaagc ugucgcuuac ggugcagcug     1200

uccaagcagc aauacuaaug ggagauaaaa gcgagaaugu gcaagacuua uuauuauuag     1260

acguugcacc ucuaucgcua ggacuagaaa cagcaggagg aguaaugaca gcacuuauaa     1320

aaagaaacag cacaauaccg acuaaacaaa cgcaaauauu uacaaccuau ucagauaacc     1380

aaccuggcgu ccuuauacag guuuaugaag gugaaagagc aaugacaaaa gauaacaauc     1440

uacuaggaag auuugagcua aguggaauac caccagcacc ucgaggagua ccacaaauag     1500

aaguuacauu cgacauagac gcuaauggca uucuaaaugu gacagcuacu gacaaaagua     1560

ccggaaaagc aaauaaaaua acuauuacaa acgauaaagg aagacuaagc aaggaagaga     1620

uagaacgcau gguacaggaa gcagaaaaau acaaagcgga agacgagguc cagcgagaaa     1680

gaguaagcgc uaaaaacgca uuagaaucau augcauucaa caugaaaagc gcaguagaag     1740

augaaggacu aaaagguaaa auaagcgaag cagauaaaaa gaaaguacua gauaaauguc     1800

aagaaguuau aaguugguua gaugcaaaua cuuuagcgga aaaagaugaa uuugaacaua     1860

aaagaaaaga acuagaacag guaugcaauc cuauuauauc aggauuauac caaggagcug     1920

gaggaccagg accaggaggc uucggagcac aaggaccgaa aggaggaucc ggaucagggc     1980

caacaauaga agaaguagau uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7378
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005337.2 __HsHSPA1B (opt13)

<400>  7378
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaaaagcug cagcaauagg aauagaccua ggaacaacau      120

acuccugcgu aggaguauuu cagcauggua aaguugaaau aauagcuaac gaccaaggca      180

acagaacaac ccccucauac gucgcauuca cagauaccga aagauuaauc ggagaugcgg      240

cuaaaaacca aguggcacuc aauccacaaa acacaguauu ugacgcaaaa agacugauag      300

gaagaaaauu cggcgaucca gugguucaau cagauaugaa acauuggcca uuccagguaa      360

uaaaugaugg agauaaacca aaaguacaag uaucauauaa aggagaaaca aaagcauuuu      420

auccagagga aauaaguagu augguauuaa caaaaaugaa agaaauagcu gaagcauauc      480

ucggauaccc aguaacaaac gccguaauaa caguuccagc auauuucaac gacagucaaa      540

gacaagcaac aaaagaugca ggaguaauag cuggccuaaa uguacuuaga auaauaaaug      600

aaccuacugc ugcugccaua gcauacggac uagaucgaac aggcaaagga gaaagaaaug      660

uuuuaauauu cgaccuugga ggaggaacau ucgacguaag cauuuuaaca auagaugaug      720

gaauauuuga aguuaaagcc acugcagggg auacucaccu aggaggagaa gauuucgaua      780

acaggcuagu uaaucauuuu guagaagaau uuaaaagaaa acauaagaaa gacauaaguc      840

aaaacaaaag agcaguaaga agauugagaa cagcauguga aagagcuaaa agaacgcuaa      900

gcucaagcac acaagcaagu uuagaaauag auaguuuauu ugaaggaaua gauuuuuaua      960

cuucgauaac gagagcaaga uuugaagaau uauguucaga uuuauuuaga ucaacguuag     1020

aaccaguuga aaaagcacua agagacgcaa aauuagauaa agcucaaaua caugaccuag     1080

ucuuggucgg aggcucaaca cgaaucccua aaguacaaaa auuacuucaa gauuucuuua     1140

acgguagaga ucuaaauaaa ucaauaaauc ccgacgaagc uguagcauau ggagcagcug     1200

uacaagccgc aauucuuaug ggagauaaau cagaaaaugu acaagauuug cuacuuuuag     1260

acguggcacc acuuagccua ggacuagaaa cagcuggagg aguaaugacc gcauuaauaa     1320

aacgcaacuc gacuauacca acaaaacaaa cacaaaucuu uacaacauac agugauaauc     1380

aaccaggagu acuaauacaa guauaugaag gagaaagagc aaugacuaaa gacaauaauc     1440

uacuaggacg guucgaacua agcggcauuc caccagcacc ucgaggagua ccacaaauug     1500

aaguaacauu ugauauagac gcaaacggga uauuaaacgu uacagcaacc gauaaaagca     1560

caggcaaagc aaacaaaaua acaauuacaa augauaaagg aagacuuuca aaagaagaaa     1620

uagagagaau gguacaagaa gcugagaaau acaaagccga agacgaaguc caaagagaaa     1680

gaguuagcgc uaaaaacgca cuggaaucau augcuuucaa uaugaaauca gcaguagagg     1740

acgaaggacu aaaaggcaaa auuucagaag cagacaaaaa gaaaguacua gauaaauguc     1800

aagaaguaau uagcugguua gaugcaaaua cccuggcaga gaaagaugaa uuugaacaua     1860

aaagaaaaga auuagaacaa guaugcaauc ccauaauauc aggucuguau caaggagcag     1920

gcgggccagg accaggagga uuuggagcac agggaccaaa agguggaucc gguagcggcc     1980

caacaaucga agaaguagau uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7379
<211>  2202
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005518.3 __HsHSPA1L (opt13)

<400>  7379
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaacagcaa aaggaauagc aauaggaaua gacuuaggga      120

caacuuacag uuguguugga guauuucagc acgggaaagu cgaaauaaua gcaaacgauc      180

aagguaauag gaccaccccu ucguacguag cauuuacaga uacugaaaga cuaauaggug      240

augcagcgaa aaaccaaguc gcaaugaacc cgcaaaauac aguauuugac gcaaaacggu      300

uaauuggaag aaaguuuaac gacccaguug uacaagcaga uaugaaauua uggccauucc      360

aaguaauaaa cgaaggagga aaaccuaaag uguugguauc cuauaaaggc gaaaacaaag      420

cauuuuaucc ggaagaaaua ucaucaaugg uacuaacaaa acuuaaagaa acggcagaag      480

cauuucuagg acauccaguc acaaacgcag uaauaacagu uccagcauac uuuaacgaua      540

gucaaagaca agcaacgaaa gaugcaggag uuauagcagg ucuaaaugua cuuaggauaa      600

ucaacgaacc aacggcagca gcaauagcau acggacuaga uaaaggagga caaggagaaa      660

gacauguacu aauauuugau uuaggcggag gaacauucga cguaaguaua uuaaccauag      720

augauggaau auucgaagua aaagcaacag caggggacac acacuuagga ggcgaagacu      780

ucgauaacag gcuaguaagc cauuuuguag aagaguucaa aagaaaacac aagaaagaua      840

uaucacaaaa uaaacgcgca guacgaagac ucagaacagc uugcgaaagg gcaaaaagaa      900

ccuuaagcuc uaguacacaa gcaaaccugg aaaucgauag uuuauacgaa ggaauagauu      960

ucuauacauc aaucacuaga gcuagauuug aagaacucug ugcagaucua uuuagaggaa     1020

cauuagaacc cguagaaaaa gcgcuuagag acgccaaaau ggacaaagca aaaauacaug     1080

acauaguccu aguaggugga aguacgcgua uaccaaaagu acaaagauua uuacaggauu     1140

auuucaacgg aagagaucuu aacaaaagua uaaaucccga ugaagcagua gcauacggug     1200

cagcaguaca ggcagcaaua cuaaugggag auaaaucuga aaaaguacaa gacuuacuac     1260

uguuagacgu agcaccacuu ucacuaggac uagaaacagc uggaggugua augacagcau     1320

uaauaaaaag aaauucaacu auaccaacua aacaaacaca aauauuuaca accuauagug     1380

acaaucaacc aggaguacua auacaaguau augaaggaga aagagcaaug acaaaagaua     1440

acaaucugcu aggaagauuu gaucuaacgg gaauaccacc agcaccaaga ggaguaccac     1500

aaauagaagu aacguuugac auugaugcaa auggaauacu aaacgugacc gccacagaua     1560

aaaguacugg aaaagucaau aaaauaacua ucacaaacga uaaagggaga cuaagcaaag     1620

aagagauaga aagaaugguu uuagaugcag aaaaauacaa agcagaagac gagguacaaa     1680

gagagaaaau agcagcuaaa aaugcauuag aaucauaugc auuuaauaug aaaagcguag     1740

uaucagacga aggauuaaaa ggaaaaauaa gcgaaaguga uaaaaacaaa auacuagaca     1800

aaugcaauga acuauuauca ugguuagaag uaaaucagcu agcagaaaaa gaugaauuug     1860

accauaaaag aaaggaacua gaacaaaugu guaauccaau aauaacaaaa uuauaccaag     1920

gggguugcac aggaccugca uguggaacag gauauguccc aggcagacca gcaacaggac     1980

caacgaucga agaaguggau uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     2040

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     2160

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        2202


<210>  7380
<211>  2196
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_068814.2 __HsHSPA2 (opt13)

<400>  7380
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucagcacgug ggcccgcgau agguauagau cuagggacaa      120

cauacagcug cguuggggug uuucaacacg gaaaaguaga aauaauagca aaugaucaag      180

guaacagaac cacaccaagu uacguugcau uuacagauac ugaaagguua auaggagacg      240

cagcgaaaaa ccaaguagcc augaacccaa caaauacgau cuuugacgca aaacgucuua      300

uaggacguaa auuugaggac gcgaccgucc aaagcgauau gaaacacugg ccauuuagag      360

uaguaagcga aggaggaaaa cccaagguac aaguagaaua caaaggagaa acaaaaaccu      420

uuuucccuga agaaauauca ucaaugguau uaacaaaaau gaaagaaaua gcagaagccu      480

accuuggggg aaaaguccac ucagcaguaa uaacgguacc agcauacuuu aacgauagcc      540

agagacaagc cacaaaagau gcagggacaa uaacaggacu caauguauua agaauaauua      600

augagccuac agcagcagca auagcauaug gauuagauaa gaaaggaugu gcgggugggg      660

aaaagaacgu auuaauauuu gaccuaggug gaggaacauu cgacguaagu auacuaacaa      720

uagaagaugg aaucuucgaa gugaaaagua cagcaggaga uacucaccug ggcggagaag      780

auuuugauaa ucgaaugguu ucacauuuag cagaagaguu caaacgaaag cacaagaaag      840

auauaggacc aaacaaaaga gcaguacgaa gauugcgaac agcgugcgaa agagcgaaaa      900

gaacacugag uucaucaaca caagcgagca uagaaauaga cucacuuuau gaaggaguag      960

auuuuuauac aaguauaaca cgcgcaagau uugaagaguu aaaugcagau uuauucagag     1020

gaacguuaga accgguugag aaagcacuaa gagacgcaaa acuugacaaa ggccaaauac     1080

aagaaauagu auuagucggc ggaucaacua gaauaccaaa aauacaaaaa cuacugcaag     1140

acuucuuuaa uggaaaagaa cucaacaaaa gcauaaaucc agacgaagca gucgcauaug     1200

gugcagcagu acaagcagca auauuaauag gggauaaauc agaaaacgug caagaucuac     1260

uguuacuaga ugucacacca cuaucacuag guauagaaac agcagggggu guaaugacac     1320

cucuaauaaa aagaaauaca accauuccaa caaaacaaac acaaacauuu acaaccuacu     1380

cagauaauca aucaagcguu cuaguacaag uauaugaagg ugaaagagca augacgaagg     1440

auaauaauuu auuaggaaaa uucgaucuca cagguauacc accagcgccc cgaggaguac     1500

cacaaauuga aguaacuuuu gacauagaug caaacggaau cuuaaauguu acagcagcag     1560

auaaaagcac cggaaaagaa aauaaaauca cuauaacgaa ugauaaagga agauuaagca     1620

aagaugauau agauagaaug guacaagaag cggaaagaua caaaagugaa gacgaagcaa     1680

auagagauag aguggcagcc aaaaaugcac uagaaagcua uacauauaau aucaaacaaa     1740

cagucgaaga ugaaaaacua agaggaaaga uaucagaaca agauaaaaac aaaauauugg     1800

acaaauguca agagguaaua aacugguuag auagaaauca aauggcugaa aaggaugaau     1860

augaacauaa acaaaaagaa uuagaaagag uaugcaaucc uauaauauca aaacuauauc     1920

aaggaggacc aggaggagga agcggaggag gaggaagcgg cgcaucaggu ggaccaacca     1980

uagaggaagu agauuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2040

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2160

ccccccccaa aggcucuuuu cagagccacc agaauu                               2196


<210>  7381
<211>  2799
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002145.3 __HsHSPA4 (opt13)

<400>  7381
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aguguuguug guauugauuu aggcuuccaa agcugcuaug      120

uggcaguugc acgagcggga ggcauagaaa caauagcaaa ugaauacagc gaucgaugca      180

cccccgcaug uaucucauuc ggaccuaaaa acagaucaau cggagcagcg gcaaaaucac      240

aaguaauuuc aaaugcgaaa aacacuguac agggauucaa aagauuucau ggaagggcau      300

ucagugaccc auuuguagaa gcugaaaaga guaacuuggc uuaugauaua gugcaacuac      360

caaccggcuu aacaggaaua aaaguaacau acauggaaga agaaagaaac uuuacaacag      420

aacaaguuac cgcaauguua cuuaguaaau uaaaagaaac ugcagaaagc guguuaaaga      480

aaccaguagu agauuguguu gugaguguac ccugcuuuua cacagaugcg gaaaggagau      540

cuguaaugga cgcuacacaa auagcgggac uaaacugcuu aagacuaaug aaugaaacaa      600

cagcagucgc auuagccuac ggcauuuaua aacaagacuu acccgcauua gaagaaaaac      660

caagaaacgu aguuuuugug gacaugggac acucagcaua ucaaguauca gugugugcau      720

uuaauagagg caaacuaaaa guauuagcaa cagcauuuga caccacacua ggaggaagga      780

aauucgauga aguacuugua aaccauuucu gugaagaguu cggcaagaaa uauaaacuag      840

auauaaaauc aaaaauaaga gccuuauuac gacuuucaca agaaugugaa aaauuaaaga      900

aacugauguc agcaaaugcc uccgaucugc cacuaaguau agaaugcuuc augaaugaug      960

uagaugucuc aggaacgaug aaccgcggua aauuuuuaga aaugugcaau gaucuauugg     1020

caaggguaga accaccgcuu agaagcgucc uagaacaaac caaacuaaag aaagaagaua     1080

uauaugcugu agaaauuguc ggaggagcaa caagaauccc agcaguaaaa gagaaaauaa     1140

guaaauucuu uggaaaagaa uuaucaacaa cgcuaaaugc agacgaagcc guaacacgag     1200

gaugcgcauu acagugugcc auacuaaguc cagcauucaa aguaagagag uucaguauaa     1260

ccgacguugu accauacccu auaaguuuaa gguggaauag ucccgcagaa gaagguagcu     1320

cagauuguga aguauuuucu aaaaaucacg cagcaccauu uucaaaagua uuaacauucu     1380

acagaaaaga gccuuuuaca cuagaggcuu auuauucauc accccaagac cuaccauacc     1440

cugauccagc uauagcacaa uucagcguac aaaaagugac accacaaagc gaugggagua     1500

gcucaaaagu aaaaguaaaa guaagaguca acguacaugg aauauuuuca guaaguagug     1560

caagccuagu agaaguacau aaaucagaag aaaaugaaga accuauggaa acagaucaaa     1620

acgcgaaaga agaagagaaa augcaaguug aucaagaaga accccauguc gaagaacaac     1680

aacaacaaac accagcugaa aauaaagcag aaagcgagga aauggaaacc agccaagcug     1740

gauccaaaga caagaaaaug gaucaaccac cccaagcaaa gaaagcaaaa guaaaaacua     1800

gcacagucga cuuaccaaua gaaaaccaac uccuauggca gaucgacagg gaaaugcuaa     1860

aucucuauau agaaaaugag ggaaaaauga uaaugcagga caaacuagaa aaagagagga     1920

acgacgcuaa aaacgcagua gaagaauacg uauacgaaau gagagauaaa cuaucagggg     1980

aauaugaaaa auuuguaucu gaagaugaua gaaacaguuu uacauuaaaa uuggaagaua     2040

cugaaaacug guuauacgaa gauggcgaag accaaccaaa acaaguauac gucgacaaac     2100

uagcugaacu aaagaaucua ggucaaccaa uaaaaauaag auuccaagaa ucagaagaaa     2160

gaccaaaauu auucgaagaa cuaggaaaac aaauacaaca auauaugaaa auaaucucau     2220

cauuuaaaaa uaaagaagac caauacgacc aucuagaugc agcagauaug acaaaaguag     2280

aaaaaucuac uaacgaagca auggaaugga ugaauaauaa auuaaaccuc caaaauaaac     2340

aaucacugac gauggauccc guuguuaaaa gcaaagaaau agaggcaaaa auaaaagaac     2400

uaacaagcac guguaguccc auaauaucaa aaccaaaacc aaaaguagaa cccccaaaag     2460

aagaacagaa aaaugccgaa caaaaugguc caguagaugg acaaggagac aauccaggcc     2520

cacaagcagc agaacaagga acagauacag ccgugccauc agauagugac aagaaauuac     2580

cagaaaugga uauugauuaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu     2640

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc     2760

cccccccccc caaaggcucu uuucagagcc accagaauu                            2799


<210>  7382
<211>  2796
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_055093.2 __HsHSPA4L (opt13)

<400>  7382
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agcguuguug gcauagaucu cggauuccua aacugcuaua      120

uagccguagc uagaagcggu ggaauagaaa caauagcgaa cgaauacucg gaccgcugca      180

caccagcuug uaucagcuua ggaucccgca ccagagcaau aggcaaugca gcgaaaagcc      240

aaauagugac aaacguacga aauacuauac auggauuuaa aaaacuacac ggaaggaguu      300

ucgaugaccc uauaguacaa acggaaagaa uacgacuccc auaugaacua caaaagaugc      360

cgaauggaag ugcaggagua aaaguaagau accucgaaga agaaagaccc uuugcaauug      420

aacaaguaac uggaauguua cuagcaaaau uaaaagaaac aucggaaaac gcauuaaaaa      480

aaccgguugc cgacugcgua auauccaucc caaguuuuuu uacggaugca gaaagaagaa      540

guguaauggc ggcagcacaa guagcaggau uaaauugccu aaggcucaug aacgaaacga      600

cagcaguagc uuuagcauac ggaauuuaua aacaagauuu gccaccauua gaugagaaac      660

ccagaaaugu aguauucaua gacaugggac acucugccua ucaaguacuc guuugugcau      720

ucaauaaagg caaauuaaaa guuuuagcca caacauucga ucccuaccuc ggcggaagga      780

auuucgacga agcauuagua gauuauuuuu gcgaugaauu caaaacaaaa uacaaaauaa      840

augugaaaga aaacuccaga gcauuacuca gacuauacca agaaugugaa aaacuaaaaa      900

aacuaaugag cgcaaaugca agcgaccucc cccuaaacau agaaugcuuu augaaugacu      960

uggacguauc uucaaaaaug aacagagccc aauucgagca auuaugcgcg ucauuacuag     1020

cccgaguaga accuccacuu aaagcaguaa uggaacaagc aaacuuacaa cgagaagaua     1080

uaucaucuau agagauugua ggaggagcaa caagaauccc cgcaguaaaa gaacagauca     1140

cuaaguuuuu uuuaaaagac auuucuacaa cacucaaugc cgaugaagcc guugcacgag     1200

gaugugcauu acaaugcgcc auauuauccc cagcauuuaa gguaagagaa uucagcauua     1260

cagaccuggu uccauauuca auaacauuaa gauggaaaac aaguuuugaa gacggaucag     1320

gugaaugcga aguauucugc aaaaaccauc cagcaccauu cucuaaagua auuacauucc     1380

auaaaaaaga accauuugaa cuagaagcuu uuuauacuaa ccuacacgaa guaccauacc     1440

cagaugcaag gaucgguuca uuuacaauac aaaacguguu cccgcaaagc gacggagacu     1500

cuaguaaagu gaaaguuaaa guaagaguca auauacaugg aauauuuuca gucgccucag     1560

ccucagugau agaaaaacag aacuuagaag gagaccauag ugacgcuccu auggaaacug     1620

aaacauccuu caaaaaugaa aauaaagaca auauggauaa aaugcaagua gaccaggaag     1680

aaggacauca gaaaugccau gccgaacaua cuccugagga agaaauagau cauacaggag     1740

caaaaacaaa aucggcagua ucagauaaac aagacagauu aaaucaaacu cuaaaaaaag     1800

ggaaaguuaa aucaauagac uuaccaauac aaucgagcuu augcagacag uuaggacaag     1860

accuacuuaa cucauauauu gaaaaugaag gcaaaaugau uaugcaagac aaauuagaaa     1920

aggagaggaa cgaugccaaa aacgcagucg aagaauacgu auaugacuuc agagauagac     1980

uaggaacugu auaugaaaaa uuuauuaccc cagaagacuu aucgaaacua agcgccguuc     2040

uagaagauac agaaaacugg cuguaugagg auggagaaga ucaacccaaa caaguauacg     2100

uugacaaacu acaagaauug aaaaaauacg gacaaccaau ccaaaugaaa uacauggaac     2160

acgaagaaag accaaaagca uuaaaugauc ucggaaaaaa aauccaauua guaaugaaag     2220

uaauagaagc cuaucguaau aaagaugaaa gauacgauca ucuagacccu acagaaaugg     2280

aaaaaguaga aaaauguaua ucagaugcaa ugaguugguu aaauucaaaa augaacgcac     2340

aaaauaaacu aaguuuaacg caagacccug uaguaaaagu cucugaaauc guagcaaaaa     2400

gcaaagaacu ggacaacuuc ugcaacccca uaauauacaa acccaaaccu aaagcagagg     2460

ugccagaaga caaacccaaa gcaaauucug aacauaacgg uccaauggac ggacaaagcg     2520

gaacagaaac aaaaucagac ucaacaaaag auaguucaca acauacaaag ucaucuggcg     2580

aaauggaagu ugacuaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2640

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2700

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2760

ccccccccaa aggcucuuuu cagagccacc agaauu                               2796


<210>  7383
<211>  2241
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005338.1__HsHSPA5 (opt13)

<400>  7383
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaauuaucuu uaguagcggc aaugcuauua cuacuaagcg      120

cagcaagggc agaggaagaa gauaaaaaag aagacgucgg aacaguaguc gguauagacc      180

uaggaaccac auauucaugc gucggaguuu uuaaaaacgg aagaguugaa aucauagcaa      240

acgaucaagg aaacagaauc acaccaucau acguagcguu cacaccugaa ggagaacgac      300

ucauaggaga ugcagcaaaa aaucaauuaa caucuaaccc ugaaaacaca gucuuugacg      360

caaaaagauu gauaggaaga accuggaacg acccuucagu ucaacaagac auaaaauuuc      420

uaccauuuaa aguaguagaa aaaaaaacaa aaccauauau acaaguugau auuggaggcg      480

gucaaacaaa aacauucgca ccagaagaaa uauccgcaau gguacuuaca aaaaugaaag      540

aaacagcuga agcauaccua ggaaaaaaag uaacacaugc cguaguaaca guaccagcau      600

auuuuaauga cgcccaaaga caagcaacaa aggaugcagg aacaauagcu ggucuaaacg      660

ucaugagaau aauaaacgaa ccaacagcag cagcuaucgc auacggacua gauaaaagag      720

aaggagaaaa aaauauacua guauuugauc uaggaggagg aacauucgau guaagcuuau      780

uaacaauaga caacggaguc uuugaaguag uagcuacaaa cggugacaca cauuuaggag      840

gagaagacuu ugaucaaaga guuauggaac acuuuauaaa acuauauaaa aaaaaaaccg      900

ggaaagacgu aaggaaagau aacagggccg uacagaaacu cagaagagaa gucgaaaaag      960

caaaacgagc auuaucauca caacaccaag caagaauaga aauagaaagu uucuaugaag     1020

gagaagauuu uagcgaaacu cuaacgcgag caaaauuuga agagcugaac auggauuuau     1080

uuagaaguac caugaaacca guacaaaaag uacucgaaga cagugauuua aaaaaaagug     1140

acauagacga aauaguccua guaggagguu caacccgaau ccccaaaaua caacaacucg     1200

ucaaagaauu uuucaacgga aaagaaccga gccgaggaau aaacccugac gaagcaguag     1260

cauauggcgc agcaguucaa gcaggcguau uaagcggaga ucaagauaca ggagauuuag     1320

uacuacuaga cguaugucca cuaacucuag gaauagaaac agucggagga guaaugacca     1380

aauuaauacc uagaaacaca guaguaccga caaaaaaauc acaaauuuuc uccacagcaa     1440

gcgacaauca accaacagua accauaaaag uauacgaagg cgaaagacca uuaacaaaag     1500

auaaccauuu auuaggaaca uuugauuuaa cagguauccc accugcccca cgaggagucc     1560

cacaaauaga aguuacauuu gaaauagaug uaaaugguau ccucagaguc acagcggaag     1620

auaaaggcac uggaaauaag aauaaaauua cuauaacaaa cgaccaaaau agauuaacuc     1680

ccgaagaaau agaaagaaug guaaaugaug cggaaaaauu cgccgaagag gacaaaaaac     1740

uaaaagagag aauagauacc agaaacgagu uagaaucaua cgcauacucc cuuaagaauc     1800

aaauuggaga uaaagaaaaa uuaggcggca aauugagcuc agaagacaaa gaaaccaugg     1860

aaaaagcagu agaagaaaaa auagaauggc uugaaagcca ccaggaugca gauauagaag     1920

auuucaaagc aaaaaaaaaa gagcuagagg aaaucguaca accaauaauu ucaaaacuau     1980

acggaagugc agggccacca ccaacaggag aagaagacac cgcagaaaaa gaugaacuuu     2040

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     2100

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2160

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     2220

cuuuucagag ccaccagaau u                                               2241


<210>  7384
<211>  2208
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002146.2__HsHSPA6 (opt13)

<400>  7384
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcaccac gugaacuugc agucgguaua gaucuaggaa      120

caacauauuc cuguguagga guauuucaac aagggagagu agaaauauua gcaaacgauc      180

aaggcaauag aacaacacca ucauauguag cauuuacuga cacagaaaga uugguaggag      240

augcagccaa aagucaagca gcauuaaauc cacauaacac aguguucgac gcgaaaagac      300

uaauugguag aaaauuugcg gauacaacag uccaaaguga caugaagcau uggccauuua      360

ggguaguguc ugaaggugga aaaccaaaag uaagaguaug cuauagaggu gaagauaaaa      420

cauuuuaucc agaagaaauu ucaucaaugg uauuaagcaa aaugaaagag acagcagaag      480

cauaccuugg acaaccagua aaacaugcug uaauaacagu ucccgcauac uucaaugaua      540

gccaaagaca agcaacaaaa gaugcuggag caauagcugg auuaaacgug cuaagaauua      600

uaaaugaacc aaccgccgcg gcaauugcau auggauuaga uagaagagga gcaggagaaa      660

gaaacguauu aauauucgau cuaggaggag gaacauuuga cguaucaguc uuaucaauag      720

acgcaggcgu auucgaagua aaagcaacag cuggugauac ucacuuagga ggagaagauu      780

ucgauaacag auuaguuaau cacuucaugg aagaauuucg acgaaaacau ggcaaagauc      840

uauccggcaa uaaaagagca uuaagaagac uacgaacagc gugugaaaga gcaaaaagaa      900

cauuauccuc aucuacccaa gcuacauuag aaauagauag ccuauucgaa gggguagauu      960

uuuacacuuc cauaacaaga gcucgcuucg aggaacuaug cucagauuua uuuagaucua     1020

cuuuagaacc uguagaaaaa gccuuacgug acgcaaaauu agauaaagca caaauacaug     1080

acgucguauu aguaggugga aguacccgaa uaccaaaagu acaaaaacua uuacaagauu     1140

ucuuuaacgg aaaagaacua aacaaaucaa uuaauccaga ugaagcaguu gcuuacggcg     1200

cagcaguaca ggcagcagua uuaaugggag auaaauguga aaaaguacaa gauuuguuac     1260

uucuagacgu ggcaccccua agccuaggau uagaaacagc aggaggagua augaccacau     1320

uaauacaaag aaaugcaaca auaccuacua aacaaacaca aacauuuaca acauauagug     1380

acaaucaacc ugggguauuc auacaaguau augaagguga aagagcaaug acaaaagaua     1440

auaauuuacu agguagauuu gaauuaucag ggauuccacc agcaccacga ggaguaccgc     1500

aaauagaggu gacuuuugac auagacgcaa auggcaucuu aagcguaaca gcaacagaua     1560

gaagcacagg aaaagcaaac aaaauaacaa uaacaaauga caaaggaagg uuaagcaaag     1620

aggaggucga aaggauggua caugaagcag agcaauauaa ggccgaagau gaagcccaaa     1680

gagacagagu agcagcuaaa aauucacuag aagcacaugu guuucacgua aaagggagcu     1740

uacaagaaga gaguuuaaga gauaaaauac cagaagaaga uagacgaaaa augcaagaua     1800

aaugcagaga aguauuagca uggcuagaac auaaucaacu ggcagaaaaa gaagaauaug     1860

aacaucaaaa acgagaauua gaacaaauau gcagaccaau auucucaagg cuauauggcg     1920

gaccaggagu accaggagga aguucuugug gaacucaagc uagacaagga gacccuucua     1980

caggaccaau aauugaagaa guagauuaag gacuaguccc uguucccaga gcccacuuuu     2040

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2160

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2208


<210>  7385
<211>  1380
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__P48741__HsHSPA7 (opt13)

<400>  7385
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caagcaccca gagaauuagc cguaggaaua gaccuaggaa      120

cuacauauag cugugucgga guauuucaac aaggaagagu ugaaauauua gcaaaugacc      180

aaggaaauag aacaacaccu ucauauguag cauucacaga cacagaaagg uuaguaggag      240

augccgcgaa aagccaagca gcauuaaacc cacacaauac aguauucgau gcaaaaagac      300

ucaucggaag aaaauuugca gauacaacag uacaaucaga uaugaaacau uggccauuuc      360

aaguagucuc agaaggcgga aaaccaaaag uaagaguaug uuacagagga gaagauaaaa      420

cauuuuaucc agaagaaaua ucaaguaugg uauuaucaaa gaugaaagaa acagcagaag      480

cauaucuagg ccaaccagua aaacaugcag uaauaacagu accaacuuau uucucaaauu      540

cacaaagaca agcaacaaaa gaugcuggag caauugcagg ucuaaaagua uuaccaauca      600

uaaaugaagc uacagcugca gcaauagcau auggccuaga uagaagagga gcaggaaaaa      660

gaaauguauu aauauuugau uuaggaggag gaaccuuuga cguaucagua uuaucaauag      720

augcaggagu auuugaagua aaagcaacag ccggagauac acaucuagga ggagaagauu      780

ucgacaacag auuaguuaau cacuucaugg aagaauuuag aagaaaacac ggaaaagacu      840

uaucagguaa uaaaagagca cuuagaagau uaagaacagc augugaaaga gccaaaagaa      900

caccaucaag cucaacacaa gcgacauuag aaaucgauuc acuauucgaa ggaguagauu      960

uuuauaaauc aauaacuaga gcccgauuug aagaauuaug uucagacuua uuucgaagca     1020

cacuagaacc aguagaaaaa gcacuaagag augcaaaacu agacaaagca caaauacacg     1080

acuucguauu aggaggagga cuacacaguc auccacaagg agcugaagua gcugcaggau     1140

uauuacaaag acaaggagca gaacaagaac accaaccuua aggacuaguc ccuguuccca     1200

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1320

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1380


<210>  7386
<211>  2217
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006588.1 __HsHSPA8 (opt13)

<400>  7386
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaaaagguc cugcuguagg aauugacuua ggaacgacau      120

auucgugugu uggugucuuc caacauggga aaguagaaau uauagcaaac gaucaaggaa      180

accgaacaac accaucauac guagcuuuua cagauacaga aagauuaauc ggagacgcgg      240

cuaaaaauca aguagcaaug aauccaacaa acacagucuu ugacgcaaaa cgacuaauag      300

gaagaagauu ugaugaugca guaguucaaa gcgauaugaa acacuggcca uuuaugguag      360

uaaaugacgc aggaaggcca aaaguacaag uagaauacaa aggagaaaca aagagcuucu      420

auccggaaga aguaucaagc augguauuaa caaaaaugaa agagauagca gaggcauacu      480

uaggaaaaac aguaacaaac gcaguaguca caguuccagc auauuucaac gauagccaaa      540

gacaagcaac aaaagacgca gguacaauag caggauuaaa uguacuccgg auaauaaacg      600

aaccaacagc ugcugcaauc gcguauggac uagauaagaa aguaggcgca gaaagaaaug      660

uauuaaucuu cgacuuagga ggaggaacau ucgauguauc uauucuaaca auagaagacg      720

gcauauucga aguaaaaagc acagccggcg acacacacuu aggaggagaa gauuucgaua      780

accgaauggu aaaccauuuc auagccgagu ucaaaaggaa acacaagaaa gacauaagug      840

aaaauaaaag agcaguacgc cgauuaagaa ccgcauguga aagagcaaaa agaacucuaa      900

guucaagcac acaagcgagu auagaaauag acaguuuaua ugaagguaua gauuuuuaua      960

caucaauaac aagagcaaga uucgaagaac uuaacgcaga ccuauuuaga ggaacacuag     1020

acccaguaga aaaagcacua agagaugcaa aauuagacaa aagccaaaua caugauauag     1080

uauuggucgg aggaucgacu agaaucccaa aaauacaaaa acuauuacaa gacuucuuua     1140

acggaaaaga acucaauaaa ucgauuaauc cagaugaagc agucgcauau ggagcugcgg     1200

uacaagccgc gauauuaagc ggagacaaau ccgaaaacgu ccaagaucua uuacucuuag     1260

acguaacacc ucugucgcua ggaauugaaa cagccggugg gguaaugaca guacuaauaa     1320

aaagaaacac cacaauacca acuaaacaaa cacaaacauu uacuacauac ucagauaauc     1380

aaccaggagu ccuaauucaa guuuacgaag gggaacgugc aaugacaaaa gacaauaauu     1440

uacucggaaa auuugaacua acaggaauac caccagcacc aagaggagua ccacaaauag     1500

aaguaacauu ugauauagau gcaaauggaa uacuaaacgu aagugcggua gauaaaagca     1560

cagguaaaga aaacaaaaua acaauaacua acgacaaagg cagauuauca aaagaagaua     1620

uagaaagaau ggugcaagaa gcagaaaaau auaaagcaga agacgaaaaa caaagagaua     1680

aaguaaguag uaaaaauuca uuagaaucau acgcauuuaa uaugaaagca acgguagaag     1740

augaaaaauu gcaaggaaaa auaaacgaug aagauaagca gaaaauuuua gacaaaugua     1800

acgaaauuau aaauugguua gauaaaaauc aaacagcaga gaaagaggaa uuugaacauc     1860

aacaaaaaga auuggaaaag gucugcaauc cuauaauaac caaauuauac caaucugcgg     1920

gaggaaugcc aggcggaaug ccaggaggau ucccaggugg aggagcucca ccaagcggag     1980

gagcaagcag uggaccaaca auagaagaag ucgauuaagg acuagucccu guucccagag     2040

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2100

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2160

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2217


<210>  7387
<211>  2316
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004125.3 __HsHSPA9 (opt13)

<400>  7387
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aucagugcaa gcagagcugc cgcagcaaga uuaguaggag      120

cggcagcaag cagaggacca accgcugcua gacaucaaga uaguuggaau ggauuaucac      180

acgaagcauu uagacucgua aguagacgag acuaugcaag cgaggcaaua aaaggcgcag      240

uaguagggau cgauuuaggg acgacaaacu caugcguagc agucauggaa ggaaaacaag      300

caaaaguacu agaaaaugca gaaggagcga gaacaacacc aucaguagua gcguuuacug      360

cagauggaga aaggcuagua ggcaugcccg cuaaaagaca agcaguaaca aauccaaaua      420

auacauuuua ugcaacaaaa agauuaauag gaagaagaua ugaugaccca gagguacaga      480

aagacaucaa aaauguaccu uuuaaaauag uaagagcaag uaacggagac gcauggguag      540

aagcacaugg uaaacuauau aguccgucgc aaauaggagc auuuguucuu augaaaauga      600

aagaaacggc agaaaauuau cuagggcaua cagccaagaa cgcaguaaua acaguacccg      660

cauauuucaa cgauucacag cgucaagcaa cgaaagaugc gggacaaauu agugggcuga      720

auguauuaag aguaauaaac gaacccacag cugcagcccu agcguaugga cucgauaaau      780

cagaagacaa aguaaucgca guauaugauu uagguggggg aaccuuugac auuucaauau      840

uagaaauaca aaaaggcgua uuugaaguaa aaaguacaaa uggagauaca uucuuaggag      900

gagaagacuu cgaucaagcu cuauuacgac auauagugaa agaguucaaa agagaaacag      960

gaguugacuu aacaaaagau aacauggcac uacaaagagu aagagaagca gcugaaaaag     1020

cgaaaugcga acuaaguagu aguguacaaa cagacauaaa cuuaccauac uuaacaaugg     1080

acucaucagg gccaaaacau cuuaacauga aacugacuag agcacaauuc gaaggaauag     1140

ucaccgaucu aauacguagg accauugcac caugccagaa agcaaugcag gacgcagaag     1200

uaucgaaaag cgauauagga gaaguaauau uaguuggggg aaugacaaga augccuaaag     1260

uacaacaaac aguacaagau uuauuuggaa gggcaccauc aaaagcagua aacccagacg     1320

aagcaguggc gauaggagcc gcaauacaag gaggaguacu agcaggagac guaacugaug     1380

uuuuauuacu agauguaacc ccacuaaguu ugggaauaga aacauuagga ggaguauuua     1440

caaaacuaau aaauagaaau accacaauac cuacaaagaa aucucaagua uuuucaacag     1500

cagcagacgg ccaaacacaa guggaaauaa aaguauguca aggcgaaaga gaaauggcag     1560

gagacaauaa acuguuagga caauuuacuu uaauagguau accaccagca ccaaggggag     1620

uaccucaaau ugaaguaaca uucgacauag acgcaaaugg aauaguccau guaucagcga     1680

aagauaaggg cacagggagg gaacaacaaa uaguaauaca aaguagcgga ggacugagua     1740

aagacgauau agaaaauaug gucaaaaaug cugaaaaaua ugcugaagag gauaggagga     1800

agaaagaaag gguagaagcg guaaauaugg cagaaggaau aauacaugac acagaaacaa     1860

aaauggaaga auuuaaagau caauuaccag cggaugaaug uaauaaacuc aaagaagaaa     1920

uaaguaaaau gagagaguua cuugcaagaa aagauucaga aacgggagaa aauauacgac     1980

aagcagcaag uucacuacaa caagcuaguc uaaaauuauu cgaaauggcc uauaagaaaa     2040

uggcaucgga acgagaagga ucaggaucau cugguacagg ggaacaaaaa gaagaucaaa     2100

aagaagaaaa acaauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     2160

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     2280

ccccccccaa aggcucuuuu cagagccacc agaauu                               2316


<210>  7388
<211>  2304
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_079291.2__HsHSPA12A (opt13)

<400>  7388
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcugauaaag aagccggagg aucugauggc ccuagagaaa      120

ccgcaccaac uucagcauau agcagccccg ccagaucauu aggagauaca ggcauaacuc      180

ccuuaucacc aucccauaua guaaacgaua cagauaguaa ugucuccgaa caacaaucau      240

uuuugguugu uguagcaguc gauuucggua caacaagcuc cggauacgca uauuccuuca      300

caaaagaacc ggaauguaua cauguuauga gaagauggga aggcggcgac ccaggaguua      360

guaaccaaaa gacuccaacu acaauccucu uaacaccgga aaggaaauuc cauucauucg      420

gauaugccgc acgcgauuuu uaccacgauu uagacccaaa cgaagcgaaa caaugguuau      480

aucuagaaaa auuuaaaaug aaacuacaua ccacaggaga ccuuacuaug gauacagacc      540

uaacagcugc aaauggaaag aaaguaaaag cauuagaaau cuuugcauac gcguuacaau      600

acuuuaaaga acaagccuua aaagaauuaa gcgaccaagc uggaucagaa uuugaaaauu      660

ccgacguacg augggucaua acgguaccug caauauggaa acaaccagca aaacaauuca      720

ugagacaagc cgccuaucaa gcuggacuag cgucaccaga aaacagcgaa caacuaauaa      780

uagcacuaga accagaagca gcaucaaucu auuguagaaa acuaagauua caucaaauga      840

uagaacuauc aucaaaagcu gcaguaaaug gauauucagg aagugacacc guaggugcag      900

gauuuacuca agccaaagaa cacauaagaa gaaauagaca aucuagaacc uuucuagucg      960

aaaauguaau uggcgaaaua uggucugaau uagaagaagg agacaaauau gucguaguug     1020

acuccggugg aggaacagug gaucucaccg uccaucaaau acgacuacca gaaggacauc     1080

uuaaagaacu cuacaaagcu acaggaggac cauauggcuc auuaggcgua gauuaugaau     1140

uugaaaaacu gcuauacaaa aucuucggag aagacuuuau agaacaauuu aaaaucaaaa     1200

gaccagcagc auggguagau uuaaugauag cauucgaauc aagaaaaaga gcugcagcac     1260

cagaucgaac uaauccguua aauauaacgu uaccauucuc auucauugac uacuauaaaa     1320

aguuuagagg ucauaguguu gaacaugcac uaagaaaauc gaauguagau uuuguaaaau     1380

ggucaaguca aggcauguua agaaugucac cagaugccau gaaugcauua uuuaaaccaa     1440

cuauagauuc aauaauagaa cauuuaagag acuuauucca aaaaccagaa guaucuacag     1500

uuaaauucuu auuccuagua gggggauuug cagaagcucc acuucuacaa caagcagugc     1560

aagcagcauu cggcgaccaa ugucgaauaa uaauaccuca agacguaggc cucacaauac     1620

uaaaaggagc gguauuauuu ggauuagauc cugcagucau aaaaguaaga agaucaccuc     1680

uaacauacgg uguaggagua cuaaacaggu acguagaagg aaaacaccca ccugaaaaac     1740

uuuuagucaa agacggaacu agauggugca cagauguauu ugauaaauuc auaucagcag     1800

aucaaucagu agcauuagga gaacugguaa aacgaucaua cacuccugcu aaacccagcc     1860

aauuaguaau cguaauaaau auauauucaa gugaacauga uaaugucuca uuuauaacag     1920

auccaggagu aaagaaaugc ggaacauuga gauuggaccu cacaggaaca ucaggaacag     1980

cuguaccagc aagacgagaa auucaaacac uaaugcaauu uggagauacc gaaauaaaag     2040

caacugcaau agauauagcc accagcaaaa guguaaaagu gggaaucgau uucuuaaauu     2100

auuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     2160

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     2280

gcucuuuuca gagccaccag aauu                                            2304


<210>  7389
<211>  2337
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_443202.3 __HsHSPA12B (opt13)

<400>  7389
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cuagcaguac cugaaauggg auuacaaggu cuauauauag      120

guagcucgcc agaacgauca ccaguaccaa guccgccggg aucaccucgc acacaagaaa      180

gcuguggaau ugcaccacua accccuucuc aaucaccaaa gccagaaguu agagcacccc      240

aacaggcuuc auuuucugua guaguagcaa uagacuuugg caccacaucc ucaggcuaug      300

ccuucagcuu ugcaucagac ccagaagcga uacauaugau gaggaaaugg gaaggaggag      360

auccaggggu agcacaucag aaaacaccua cuugcuuauu acuaacacca gaaggcgcau      420

uucauaguuu uggauauaca gcaagagacu auuaucauga ucuggauccu gaagaagcgc      480

gugauugguu auauuuugaa aaauuuaaaa ugaaaaucca uucagcaaca gaucuaacuu      540

uaaaaacaca auuagaagcu gucaauggca aaacaaugcc agcauuagaa guauuugccc      600

augcacuaag auuuuuccga gaacaugcac uacaagaacu uagagaacaa uccccaaguu      660

uaccugagaa agauacagua agauggguau uaacagugcc ggcaauaugg aaacaaccug      720

cuaaacaauu caugagggaa gccgccuauu uagcaggauu gguuucacga gaaaacgcag      780

aacaacuauu gauagcuuua gagccagagg cggcaagugu auauuguaga aaacuaagau      840

uacaucaacu acuagauuua ucaggcagag cuccaggagg agguagauua ggagaaagac      900

gauccauuga uucuaguuuu agacaagcua gagaacaacu aagaagaagc agacauucaa      960

gaacauuccu uguagaaagu ggaguaggag aauuaugggc agaaaugcaa gcaggagaua     1020

gauauguagu ugcagacugu ggaggaggaa cuguagaccu cacaguucau caacuagaac     1080

aaccacaugg uacccuaaaa gaauuauaua aagcgagugg cggcccauac ggagcaguag     1140

gcguagauuu agcauuugaa caauuacucu gucgaauauu uggagaagau uucauagcua     1200

cuuuuaaaag acaaagacca gcugcauggg uagaucuaac uauagcuuuc gaagcaagaa     1260

aaagaacagc cggaccucau agagcaggag cauuaaauau aucucuacca uuuaguuuua     1320

uagauuuuua cagaaaacaa cggggacaua acguagaaac ggcauuacga agaucaagug     1380

ucaacuucgu aaaaugguca ucacaaggua uguuaagaau guccugugaa gcaaugaaug     1440

aacuauuuca acccacugua agcggaauaa uacaacacau agaagcauua uuagcaagac     1500

ccgaaguuca aggaguaaaa uuacuauuuc uaguaggagg guuugccgaa ucggcaguuc     1560

uacaacaugc aguacaagcu gcguuaggcg cacgaggauu acgaguagua guaccccacg     1620

auguugggcu uacaauucug aaaggagcug uauuauuugg acaggcacca ggaguaguca     1680

gaguuagaag aagcccacua acauaugggg uaggaguacu uaacagauuu guaccaggca     1740

ggcauccucc agaaaaauua uuaguacgag acggaagacg uugguguaca gauguauucg     1800

aaagauucgu ugcagcugaa caaagcguug cauuaggaga agaaguaaga cgaucauauu     1860

gcccagcuag accaggucaa agaagaguuc uaauaaacuu auauuguugc gccgcagaag     1920

augcaagguu uauuacugau ccuggaguuc gaaaaugugg ugcacuuagc cuagaacuag     1980

aaccggccga uuguggacaa gauacagccg gagcaccacc agguagaaga gaaauaagag     2040

cugcuaugca auucggagac accgaaauaa aagucacagc aguagauguc agcacaaaua     2100

gaucagugcg agcuaguaua gacuuucuau caaauugagg acuagucccu guucccagag     2160

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     2220

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     2280

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        2337


<210>  7390
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_008879.3__HsHSPA13 (opt13)

<400>  7390
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcacgagaaa ugaccauauu aggaagcgcc guauuaacau      120

uauuacuagc gggauauuua gcacaacaau aucuaccccu acccacacca aaaguaaucg      180

gaauagacuu aggaacaaca uauuguagug uaggaguuuu cuucccagga accggaaaag      240

ucaaaguaau accagacgaa aacggacaca uaucaauucc aucaauggua ucauuuacug      300

auaacgacgu auauguagga uacgaaucag uagaauuagc cgauagcaau ccacaaaaca      360

cuauauauga cgcaaaaaga uucauaggca aaauauuuac agcagaagaa cuugaagcug      420

aaauaggaag auaucccuuu aaaguacuaa auaaaaacgg aaugguagaa uucucaguua      480

caucaaauga aacaauaaca gucaguccag aauacguagg uagcagauua cuacuaaaac      540

uaaaagaaau ggcagaagca uacuuaggaa ugccaguagc aaaugccgua auaucuguac      600

cagcagaauu cgauuuaaaa caacgaaauu caacaauaga agcagcuaau cuagcaggac      660

uaaaaauauu aagaguuaua aacgaaccca cagcagcagc aauggccuau ggauuacaca      720

aagcugacgu auuucaugua cuaguaauag aucuaggugg agguacauua gacguaagcu      780

uacuaaauaa acaaggaggc auguuucuua cacgagcaau gucaggcaac aacaaauuag      840

gaggucaaga cuuuaaccaa agacuacuac aauaucucua caaacaaauu uaccaaacuu      900

auggauuugu uccuucaaga aaagaagaaa uacaucgauu acgacaagca guagagaugg      960

uaaaacuaaa uuuaacacua caucagagug cacaacuuuc cgucuuauua acaguugaag     1020

aacaagaucg aaaagaacca cacaguucag acaccgaacu uccaaaagau aaauuaagcu     1080

cagcagauga ccauagaguu aacagcggcu uuggaagagg auuaucagac aaaaaaagcg     1140

gagaaagcca agugcuguuu gaaaccgaaa uaagcagaaa auuauucgau acacuuaacg     1200

aagaccuauu ccaaaaaaua uuaguaccaa uccaacaagu acuaaaagaa ggucaucuag     1260

aaaaaacaga aauagaugag guaguauuag uaggaggauc aacacguaua cccagaauaa     1320

gacaaguaau acaggaauuu uucggaaaag auccaaauac aucaguagac ccagauuuag     1380

cgguuguuac aggagucgca auacaagcag gaauagaugg cggaagcugg ccauuacaag     1440

uauccgcacu agagauccca aacaaacauc uacaaaaaac caauuucaau uaaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  7391
<211>  1806
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057383.2__HsHSPA14 (opt13)

<400>  7391
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcagcaauag gaguacauuu aggauguaca agugcaugug      120

uagcaguaua uaaagaugga agagcaggag uaguagccaa ugaugcaggg gauagaguaa      180

caccagcggu aguagcuuau ucagaaaaug aagaaauagu aggauuagcu gcaaaacaau      240

caagaauaag aaauauuagu aacaccguaa ugaaagugaa acaaauacua ggaagaucuu      300

caucagaucc ccaagcacaa aaauauauag cagaaucaaa augucuagua auagaaaaaa      360

auggcaaacu aagauaugaa auagauacag gcgaagaaac aaaauuugua aacccugaag      420

augucgcuag acuaauauuc ucaaaaauga aagaaacagc acauucagua cuaggaucag      480

augcaaauga cguaguaaua accguaccau uugauuuugg agaaaaacaa aaaaaugcau      540

uaggagaagc agcaagagca gcaggauuua acguguuacg acuuauacau gaacccucag      600

cagcauuauu agccuaugga auaggucaag acucaccaac aggcaaauca aauauauuag      660

uauuuaaauu aggaggaacu agucuaucac ucucaguaau ggaaguaaau ucaggaauau      720

acagaguuuu aucaacuaau acagaugaua auauuggagg agcacauuuu acagaaacau      780

uagcucaaua ccuugcaagu gaauuucaaa gaaguuuuaa acacgauguc agaggaaaug      840

caagagcaau gaugaaacua acgaauucag cagaaguagc aaaacauuca uuaucaacau      900

uagggucugc caauuguuuc cuagauaguc uuuaugaagg gcaagacuuu gacuguaaug      960

uaagucgagc aagauuugaa cuacuguguu caccccuguu uaacaagugc auagaagcaa     1020

uaaggggauu acuagaucaa aauggcuuca ccgcagauga caucaauaaa guaguacuau     1080

guggaggaag cucaagaaua ccaaaacucc aacaauuaau aaaagauuua uuucccgcug     1140

uagaacuacu aaauaguaua cccccagaug aaguaauacc aauaggugcc gcaauagaag     1200

caggcauauu aauaggcaaa gagaaucuac uaguggaaga cagucuaaug auagaaugua     1260

gugcaagaga cauauuagua aaagggguag augaaagugg agcaagcaga uuuacaguau     1320

uauuccccag cggaacaccu cuaccagcaa gaagacaaca uacucuacaa gcgccagguu     1380

caauaucauc aguuugccua gaacuauacg aaucagacgg uaaaaacuca gcaaaagaag     1440

aaacaaaauu cgcucaagua guacuacaag auuuggacaa aaaagagaau ggacuaagag     1500

auauucuagc cguauugacu augaaaagag auggaucacu acacguaaca uguacagacc     1560

aagaaacagg aaaaugugaa gcaaucucua uagaaauagc cucauaagga cuagucccug     1620

uucccagagc ccacuuuuuu uucuuuuuuu gaaauaaaau agccugucuu ucagaucuaa     1680

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1740

aaugcauccc cccccccccc cccccccccc ccccccccaa aggcucuuuu cagagccacc     1800

agaauu                                                                1806


<210>  7392
<211>  2853
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006635.2 __HsHSPH1 (opt13)

<400>  7392
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aguguugugg ggcuagacgu agggagccaa aguugcuaua      120

uagcaguagc cagagccgga ggaauagaaa cgauagcaaa ugaauucuca gauagaugca      180

ccccaagugu aauaucauuc ggaucaaaaa acaggacgau aggaguggca gccaaaaauc      240

aacagauaac gcacgcaaau aacacaguca gcaacuuuaa aagauuucac ggaagagcau      300

uuaacgaccc auuuauacaa aaagaaaaag agaaucuaag uuacgacuua gucccccuaa      360

aaaauggagg agugggaaua aaaguaaugu auaugggcga agaacaccuu uuuucaguug      420

aacaaauaac ugcgaugcua uuaacaaaac uaaaagaaac agcagaaaac ucauuaaaaa      480

aaccaguaac agacugcgua auaucaguac caucauucuu uacagacgcu gaacgacgaa      540

guguucuaga cgcagcacag auaguagguu ugaauugucu aagacugaug aacgacauga      600

cagcaguagc guuaaacuac ggaauauaca aacaggaccu accaagcuug gacgagaaac      660

cuagaauagu aguauucgua gacauggggc acucugcauu ccaaguuagu gcaugcgcau      720

ucaauaaagg uaaacucaaa guauuaggaa cagcauuuga cccauucuua ggaggcaaaa      780

acuuugacga aaaacuuguu gaacauuucu gcgcggaauu caaaacaaaa uauaaauugg      840

acgccaaaag caaaauaaga gcccuuuuac gacuauacca agagugcgaa aaacuaaaaa      900

aacuaaugag uaguaauuca acugaccuac cacucaauau ugaguguuuc augaaugaua      960

aagauguaag uggcaaaaug aacagaucuc aauucgaaga auuaugcgcc gaauugcuac     1020

agaaaauaga gguaccacua uauagccucc uagaacaaac acaucuaaaa guagaagaug     1080

uuagugcagu ggaaauagua ggaggcgcua caagaauacc ugcaguuaaa gaaagaaucg     1140

cuaaauucuu cggaaaagau auauccacaa cacuuaaugc agacgaagca guagcucgcg     1200

gcugcgcucu ccaaugugcc auucuaaguc cagccuucaa agucagagaa uucucuguaa     1260

cugacgcagu uccguucccu auaucacuua uauggaacca cgacagugaa gauacugaag     1320

gagugcauga aguauucagc aggaaccaug ccgcuccuuu cagcaaagua uuaacuuucu     1380

uacgaagggg accauucgaa uuagaagcau uuuacucaga uccacaagga guaccauacc     1440

cugaagcaaa aauaggccga uucguaguac aaaacgucag cgcacaaaaa gauggagaaa     1500

aaucaagagu caaaguaaag guacguguaa auacccacgg uauuuucaca auaucaacag     1560

cauccauggu agaaaaagua ccuacagaag aaaaugaaau gucaagcgaa gcagauaugg     1620

aaugcuuaaa ucaaagacca ccagaaaacc cagauacaga caaaaacgua caacaagaua     1680

acucagaagc aggaacacaa ccacaaguac aaaccgaugc ucaacaaacc ucacaaucac     1740

cuccaagccc agaacuuacu ucugaagaaa acaaaauccc agacgcagau aaagccaacg     1800

aaaaaaaagu cgaccaacca ccagaagcua aaaaaccaaa aauaaaagua guaaacguag     1860

aacugcccau agaagcaaac cuaguauggc aacuaggaaa agauuuauua aacauguaca     1920

uagaaacuga aggcaaaaug aucaugcaag auaaacuaga aaaagaacgc aaugacgcaa     1980

aaaacgcagu agaagaauau guauaugaau uuagagacaa auuaugugga ccauaugaaa     2040

aauucauaug cgaacaagau caccaaaauu uccuacgacu acucacugaa acagaagacu     2100

gguuauauga agaaggagaa gaccaagcaa aacaagcuua cguagacaaa cuggaagaac     2160

uaaugaaaau agguacgccu guaaaaguac guuuccaaga agcagaagaa agaccgaaaa     2220

uguuugaaga auuaggacag agacuccaac acuaugcaaa aauagcugca gacuuccgaa     2280

acaaagauga aaaauauaac cacauagaug aaagcgaaau gaaaaaaguu gaaaaaucag     2340

ucaacgaagu aauggaaugg augaacaacg uaaugaaugc acaagcaaaa aaaagucuag     2400

accaagaccc aguagucagg gcgcaagaga uaaaaacgaa aaucaaagaa uuaaauaaca     2460

cuugcgaacc cgucguaacg caaccaaaac cuaaaauaga aucaccaaaa cuagagcgca     2520

cgccuaaugg uccaaacaua gacaaaaaag aagaggaccu agaagauaaa aauaacuuug     2580

gugcagaacc cccccaucaa aacggagaau gcuauccaaa cgaaaaaaau aguguaaaua     2640

uggaucuaga cuaaggacua gucccuguuc ccagagccca cuuuuuuuuc uuuuuuugaa     2700

auaaaauagc cugucuuuca gaucuaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2760

aaaaaaaaaa aaaaaaaaaa aaaaaaaaau gcaucccccc cccccccccc cccccccccc     2820

cccccaaagg cucuuuucag agccaccaga auu                                  2853


<210>  7393
<211>  3276
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_006380.1 __HsHYOU1 (opt13)

<400>  7393
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcugauaaag uaagaagaca aagacccaga aggagaguuu      120

guugggcucu aguagcagua uuacuggcag auuuauuagc cuuaucagau acccuugcag      180

uaauguccgu agaccuagga agugaaagua ugaaaguagc aauaguuaaa cccggaguac      240

caauggaaau aguccuuaac aaagaaucua gaaggaaaac uccaguuaua guaacacuaa      300

aagaaaauga acgauucuuc ggcgacagug cagcaucaau ggccaucaaa aauccaaaag      360

caacauuaag auacuuucaa caucuucuug gcaaacaagc ugauaauccu caugucgcau      420

uauaucaagc aagauucccc gaacacgaac uaacuuuuga cccacaacgu caaacuguac      480

acuuucaaau aaguucacaa cuacaauuua guccagaaga aguacucgga augguccuga      540

auuauucaag aucauuagca gaagauuucg cagaacaacc uauaaaagac gcaguaauaa      600

ccguuccugu guucuuuaac caagccgaaa ggcgagcagu auuacaagca gcucgaaugg      660

caggauuaaa agucuuacaa uugauaaaug auaauacagc aacagcacuu aguuacgggg      720

uauuuagacg aaaagauauc aauacgacag cucaaaauau aauguuuuau gacaugggaa      780

guggcucaac agucugcaca auaguaacau aucaaauggu caaaacaaaa gaagccggga      840

ugcaaccaca acugcaaaua cgagguguag gauucgauag aaccuuaggg ggacuagaaa      900

uggaauuaag auuacgagaa agauuagcag gauuauuuaa cgaacaaagg aaaggccaac      960

gugcaaagga uguaagagaa aauccaagag cgauggcaaa acuccugaga gaggcuaaua     1020

ggcuaaaaac ggugcuaagc gcaaaugcgg accauauggc acaaauagaa ggguuaaugg     1080

augacguaga cuuuaaagcc aaaguaacac gcguagaguu cgaagaauua ugugcugauc     1140

uauuugaaag aguaccgggu ccaguucaac aagcguuaca aucggcagaa augucacuug     1200

augaaauaga acaaguaauu uuaguagggg gcgcuaccag gguuccuagg guacaagaag     1260

uccuauugaa agccgugggg aaagaagaau uagguaagaa uauaaacgca gaugaagcug     1320

cugcaauggg ugcaguguau caagcagcag cacuaagcaa ggcauuuaag gugaaaccgu     1380

ucguuguaag ggaugcugua gucuauccaa uauuaguaga auuuacucgc gaaguagaag     1440

aagaaccagg aauacauucc uuaaaacaua auaaaagagu cuuauucagc aggaugggac     1500

ccuauccuca gagaaaagua auaaccuuca accgauacag ucaugacuuc aauuuccaca     1560

uaaacuaugg agauuuagga uuucuugguc cggaagacuu aagaguauuu ggaagucaaa     1620

aucuaacaac cguaaaauua aaaggcgugg gagacucauu uaagaaguau cccgauuacg     1680

aaucaaaagg aauuaaggca cauuuuaacu uagacgagag cggagucuua agccuggaca     1740

gaguggaauc aguauucgaa acguugguug aagauucagc ugaagaagaa aguacacuaa     1800

cgaaauuggg aaacaccaua aguucucuau ucggaggagg cacaacucca gaugcaaaag     1860

aaaaugguac agauacuguc caagaagaag aagaaucacc agcagaagga uccaaggacg     1920

aaccaggaga gcaaguugaa cuuaaagaag aagcagaagc acccguugaa gauggaucac     1980

aaccuccacc acccgaaccg aaaggagacg ccacgccgga aggagaaaaa gcaacugaaa     2040

aagaaaaugg agauaaauca gaagcacaaa aaccaucuga aaaagccgag gcaggaccag     2100

aagguguagc ucccgcuccg gaaggugaaa agaaacaaaa accagcacga aaaagacgca     2160

uggucgaaga aauaggagua gaauuaguag uuuuagacuu accugaucuc ccagaagaca     2220

aacucgcaca aucaguacaa aaacuacaag aucuaacauu gagagaucug gagaaacaag     2280

aaagagaaaa agcagcuaau agucuagagg cuuucauuuu cgaaacccaa gacaaauuau     2340

accaaccuga auaccaggaa guuuccacag aagaacaaag ggaagaaauc agugguaaau     2400

ugagcgcagc uaguacaugg uuagaagaug aaggaguugg agcaacgaca guaauguuaa     2460

aagaaaaauu agcagaauua aggaaauuau gucaaggacu cuucuuuaga gucgaagaaa     2520

gaaagaaaug gcccgagaga uugucagcau uagacaauuu auuaaaccau uccagcaugu     2580

ucuuaaaagg ugccagacuu auaccagaaa uggaucagau auuuacagaa guggaaauga     2640

cuacacuaga aaaaguaauu aacgaaaccu gggcauggaa aaaugcaaca cuagcagaac     2700

aagccaaauu accggcgacg gagaaaccag uacuauuauc gaaagauaua gaagcaaaaa     2760

ugauggcucu agaccgagaa guccaauacc uuuuaaacaa agccaaauuu acaaaaccaa     2820

ggccaagacc uaaagacaaa aauggaacaa gagcggaacc accacuaaac gcgagcgcaa     2880

gugaccaagg ugaaaaagua auuccaccag cuggacaaac agaagacgcu gaacccauaa     2940

gugaaccaga aaaaguagaa acaggaucag aacccggaga uacugaacca cuagaguugg     3000

gaggaccagg ggcugagccc gaacaaaaag aacaaucaac aggccagaaa agaccgcuca     3060

aaaacgauga acuauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     3120

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3180

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     3240

ccccccccaa aggcucuuuu cagagccacc agaauu                               3276


<210>  7394
<211>  2475
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005339.3 __HsHSP90AA1 (opt13)

<400>  7394
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaagaaa cgcaaacaca ggaccaacca auggaagaag      120

aagaaguuga aacauuugcc uuccaagcug aaaucgcuca acuaaugucc cucauaauaa      180

acacauuuua caguaauaag gaaauauucc uacgagaauu aauaucaaau aguagugacg      240

cauuagauaa aauacguuac gaaagccuaa cagauccgag uaaacuagac ucaggaaaag      300

aacuacacau aaacuuaaua ccaaacaaac aagaccgaac acucacaaua guagacacag      360

guauaggcau gacgaaagcc gauuuaauaa acaaccucgg aaccauugca aaaagcggaa      420

ccaaggcauu cauggaagcu cuacaagcag gagcggacau cagcaugaua ggccaguucg      480

gaguggguuu cuauucagca uaccucguag cagaaaaagu aaccgucaua acgaagcaca      540

acgacgauga acaauaugca ugggaaucau ccgccggagg aaguuucaca guccgaacug      600

acacagguga acccauggga agagguacua aaguaauccu ucaucugaaa gaagaucaaa      660

ccgaauaccu cgaagaacga cgaauaaaag aaauuguaaa aaagcauuca caauucaucg      720

gauacccuau aacacucuuc guagaaaaag aaagggauaa agaaguaagc gaugaugaag      780

cagaagaaaa ggaagacaaa gaagaagaaa aagaaaaaga agaaaaagaa ucagaagaua      840

aaccagaaau agaagacgua ggauccgacg aagaagaaga aaaaaaagac ggugacaaaa      900

aaaaaaaaaa aaagauaaaa gaaaaauaca uagaccaaga agaauuaaau aaaaccaaac      960

cgauauggac gagaaauccc gacgacauaa ccaacgaaga auacggagaa uucuauaaaa     1020

gccugaccaa cgacugggaa gaccaucugg cagucaaaca cuucagugua gaaggacaau     1080

uagaauucag agcacuacua uuuguaccga gacgagcacc auucgacuua uucgaaaaua     1140

gaaaaaaaaa aaacaacaua aaauuguacg uaagaagggu cuucauaaug gacaauugug     1200

aagaacuaau acccgaauau cuaaacuuca uuagaggcgu uguagacuca gaagaccuuc     1260

cacucaauau aucaagagaa auguuacaac aaaguaaaau acugaaggua auaaggaaaa     1320

auuuaguaaa aaaaugcuug gaacuauuca cagaacuagc agaagacaaa gaaaacuaca     1380

aaaaauuuua ugaacaauuc ucaaaaaaca uaaaguuagg aauucacgaa gauagccaaa     1440

auagaaagaa acuaucugaa uuguuacgau auuauacauc cgcaucaggu gacgaaaugg     1500

ugucguuaaa agauuacugc acacgaauga aagaaaacca aaaacauaua uauuacauaa     1560

caggagaaac aaaagaucaa guagcaaaca gcgcauucgu cgaacgacug agaaagcacg     1620

gauuagaagu aauauacaug auagaaccaa uagaugaaua uuguguacaa caauuaaaag     1680

aauucgaagg aaaaacucuc guaucaguaa caaaggaagg acuugaacua ccagaagaug     1740

aagaagaaaa aaaaaaacaa gaagaaaaaa agacaaaauu ugaaaaccuc ugcaaaauaa     1800

ugaaagacau acuggaaaaa aaaguagaaa aaguaguagu cucaaacaga cuagugaccu     1860

caccuuguug uauagucaca agcacauaug gauggaccgc aaacauggaa agaauaauga     1920

aagcacaagc auuaagagau aacucaacaa uggguuacau ggcagcuaaa aaacaucucg     1980

aaauaaaucc agaucauucu auaauagaaa cucuuagaca aaaagcagaa gcagauaaaa     2040

acgacaagag uguaaaagac uuagucauac uauuauacga aacggcacua cucagcagug     2100

gauuuaguuu agaagaucca caaacacacg cgaacaggau cuacagaaug auuaaacuag     2160

gauuaggaau cgaugaagau gacccaacag cagacgacac aucagcagca guaacagaag     2220

aaaugccacc acuagaaggg gacgaugaca cuagccgaau ggaagaagua gacuaaggac     2280

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     2340

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     2400

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     2460

agagccacca gaauu                                                      2475


<210>  7395
<211>  615
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NG_005218__HsHSP90AA3P (opt13)

<400>  7395
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gacagcucaa aacuagacuc aggaaaagga cuacacauaa      120

accuaguacc aaacaaacaa aaccaaacac uaacaauagu agacacaaga auaggaauga      180

caaaaacaga ccuaauaaac aaccuaggaa caguaacaaa aagcggaaca aaagcauuca      240

uggaagcacu acaagcagac gcagacauaa gcaugauagg acacuucgga guaggauucu      300

acucagcaua ccuaguagca aaaaaaguaa caguaauauc aaaacacaac aacgacgaac      360

aauacacaug ggaaucaagc gcaggaggaa gcuucacagu aagaacagac gaauaaggac      420

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      480

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      540

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      600

agagccacca gaauu                                                       615


<210>  7396
<211>  2451
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_031381.2__HsHSP90AB1 (opt13)

<400>  7396
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccagaagaag uacaucaugg agaagaagaa gucgaaacgu      120

uugcuuucca agcggaaaua gcgcaacuaa ugagccuaau aauaaacaca uucuauagua      180

acaaagaaau cuucuugagg gaauuaauuu caaacgccuc cgaugcauua gacaaaauaa      240

gauacgaaag cuuaacagac ccaucaaaau uagauagcgg aaaagagcua aaaaucgaca      300

uaauaccuaa cccacaagaa cguacacuga cacuuguaga uacaggaaua ggaaugacaa      360

aagcagaccu aauaaacaac cuaggaacua uagcuaaauc aggcacgaaa gccuucaugg      420

aagccuuaca agcaggagca gauauaucaa ugauaggaca auuuggagug ggauucuaca      480

gcgcauaccu aguagcagaa aaaguagucg uaauaaccaa acauaaugac gacgaacaau      540

acgcauggga aagcucggca ggaggcagcu uuacaguaag agcagaucau ggcgaaccua      600

uaggaagggg caccaaaguc auccuacauc ucaaagaaga ucaaacagaa uauuuagaag      660

aaagacgagu gaaagaggua gucaaaaagc auucccaauu uauaggcuau ccaauaaccu      720

uauaccuaga aaaagaaaga gaaaaagaaa uaucagacga cgaagccgaa gaagaaaaag      780

gagaaaaaga agaagaagau aaagacgaug aagaaaaacc aaaaauagaa gauguaggaa      840

gcgaugaaga agacgacuca ggaaaagaca aaaaaaaaaa gacaaaaaaa auaaaagaaa      900

aauauaucga ucaagaagaa cucaacaaaa caaaacccau auggacaaga aauccagacg      960

acauaacaca ggaagaauac ggagaauucu auaaaagccu uacgaaugac ugggaagauc     1020

aucuagcagu aaaacacuuc ucuguagaag gacaacuaga auuccgagcc cuacuauuca     1080

uaccaagacg cgcaccauuc gaccuauucg aaaauaaaaa aaaaaaaaac aauauaaaau     1140

uauauguacg gagaguguuc auaauggaca guugcgauga acuaauacca gaauacuuaa     1200

acuuuauaag aggaguggua gacucagaag accuaccccu aaauauaagc cgggagaugu     1260

uacaacaaag caaaauauua aaaguaauca ggaagaacau uguaaaaaaa ugucuggaac     1320

uauuuucaga guuagcagaa gauaaagaaa acuacaaaaa auucuacgaa gcauucucaa     1380

aaaauuuaaa auuagggaua caugaagaca gcacaaacag aagaagacug agcgaacuac     1440

uaagauauca uacaagucaa aguggagacg aaaugacuuc acuaagugaa uacguaucaa     1500

gaaugaaaga aacacaaaaa ucuauuuacu acauaacugg agaaucaaaa gaacagguag     1560

caaacagcgc auuugucgaa cgaguaagaa aacgaggauu cgaaguaguu uauaugacag     1620

aaccuaucga ugaauauugc guccaacaac uaaaagaauu ugacggaaaa ucacuuguca     1680

guguaacaaa agaaggacua gaacugcccg aagacgaaga agaaaaaaaa aaaauggaag     1740

aaucaaaggc uaaauucgaa aaucuaugca aauuaaugaa agaaauacuc gacaaaaaag     1800

uagaaaaagu aaccauaagc aaucgacuag uaucaagucc uugcuguaua gucacaucaa     1860

cauauggaug gacagcgaau auggaaagga uaaugaaagc ccaagcacuu agagacaaua     1920

guacaauggg auacaugaug gccaaaaagc aucuagaaau aaauccugac cacccaaucg     1980

uagaaacacu aagacaaaaa gcagaagcag auaaaaacga caaagcaguu aaagacuuag     2040

uugucuuauu auucgaaaca gcacuacucu caaguggauu cucacuagaa gacccccaaa     2100

cacauaguaa cagaauauac cgaaugauua aauugggauu aggaaucgac gaagacgaag     2160

uggcagccga agaaccaaau gccgcaguac ccgaugaaau accaccccua gaaggagacg     2220

aagacgcaag uagaauggaa gaaguagauu aaggacuagu cccuguuccc agagcccacu     2280

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2340

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2400

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2451


<210>  7397
<211>  2688
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003290.1__HsHSP90B1 (opt13)

<400>  7397
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agggcauuau ggguucuagg acuauguugc guacuacuaa      120

cguucggauc aguaagagca gacgaugaag uagaugucga uggcacagua gaggaagacc      180

uaggaaaauc aagagaagga agccguacag acgacgaagu agugcaaaga gaagaggaag      240

caauccaguu ggauggacua aaugcaaguc aaauaagaga acuaagagaa aaaucagaaa      300

aauucgcauu ucaagcagaa gugaacagaa ugaugaaacu aauaaucaau ucauuauaua      360

aaaacaaaga aauauuccug agagaacuaa uaagcaacgc aagugaugcu uuagauaaaa      420

uacgacuaau uagcuuaaca gacgaaaaug cauuaagcgg aaaugaagag uuaacaguaa      480

aaauaaaaug ugacaaagaa aaaaacuuac uccaugugac agacacagga guaggaauga      540

cccgcgagga auugguaaaa aaucuaggaa cgauagcuaa aagcggaaca agugaauuuc      600

uuaauaaaau gacagaagca caagaagacg gccaaucaac aagugaacua auaggacaau      660

ucggaguugg uuuuuauagu gcuuuuuuag uugcugacaa aguaauaguc acgucgaaac      720

auaauaacga cacacaacac aucugggaaa gugacucgaa ugaauuuuca guuauagcag      780

auccaagagg aaauacgcua ggcagaggga caacaauaac auuaguacuu aaagaagaag      840

caucagauua uuuagaauua gauacaauaa aaaaccuagu aaaaaaauau agucaauuca      900

uaaauuuccc cauauaugua uggaguagua aaacagaaac gguagaagaa ccaauggaag      960

aagaagaagc agcuaaagaa gaaaaagagg aaagugacga ugaagcagca guugaagaag     1020

aagaagaaga aaaaaagccg aaaacuaaaa aagucgaaaa aacgguaugg gacugggaac     1080

uuaugaacga uauaaagccc auauggcaga gaccgagcaa agaaguagaa gaagaugaau     1140

auaaagcauu uuacaaauca uuuaguaaag aaucagacga uccaauggcu uacauacauu     1200

uuacagccga gggagaagua acauucaaau caauuuuguu uguaccaaca agugcuccca     1260

gagggcuauu cgaugaauac ggaucaaaaa aaagcgacua uauaaaacuc uauguaagaa     1320

gaguauucau caccgacgac uuccacgaua ugaugccuaa auaccuaaau uucguaaaag     1380

gagucguaga uagugaugac uuaccauuaa auguaagcag agaaacucuc caacaacaua     1440

aauuacuaaa agugauacgu aaaaaauuag uaagaaaaac acucgacaug auaaaaaaaa     1500

uagcggauga uaaauauaau gauacauucu ggaaagaauu cggaacaaau auaaaacuug     1560

gcguaauaga agaucacucu aauagaacaa gacuagcaaa acucuuaagg uuccaaagcu     1620

cacaucaccc aaccgauaua acuucauuag aucaauaugu agaaaggaug aaagaaaaac     1680

aagauaaaau auauuuuaug gcaggaucau caagaaaaga agcugaaagu agcccauucg     1740

ucgaaagacu ucuuaaaaaa ggguaugaag uuauauauuu gacagaacca guagaugaau     1800

auuguauaca ggcacuacca gaauucgaug guaaaagauu ccaaaacgua gcaaaagaag     1860

gcguaaaauu cgacgaaagu gagaaaacua aggaaucacg agaagcggua gaaaaagaau     1920

ucgagcccuu acucaauugg augaaagaca aagcacuaaa agauaaaauc gaaaaagcug     1980

uggucaguca aagauuaaca gaaucaccau gcgcauuagu ugcaagucaa uauggguggu     2040

caggaaauau ggaaagaaua augaaagcgc aagcauauca aacuggaaag gauauaucga     2100

cuaacuacua cgcaucgcaa aagaaaacau ucgaaauaaa uccuagacac ccauuaauaa     2160

gagacaugcu acgaagaauc aaagaagaug aagacgacaa gacaguacua gaucuagcag     2220

uaguauuauu ugaaacagca acauuaagau cggguuaccu ucuuccggau acaaaagcau     2280

acggcgacag aauagaaaga augcucagac uaucacucaa caucgaccca gaugcaaaag     2340

uggaagagga accagaagaa gaaccagaag aaacagcaga agauacgaca gaagacacug     2400

aacaagauga ggacgaagaa auggacgugg gaacugacga agaagaagaa acugcaaaag     2460

aaagcacugc ugagaaagau gaacuauaag gacuaguccc uguucccaga gcccacuuuu     2520

uuuucuuuuu uugaaauaaa auagccuguc uuucagaucu aaaaaaaaaa aaaaaaaaaa     2580

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaugcauc cccccccccc     2640

cccccccccc cccccccccc aaaggcucuu uucagagcca ccagaauu                  2688


<210>  7398
<211>  2391
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057376.2__HsTRAP1 (opt13)

<400>  7398
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaagagaac uaagagcucu auuacucugg ggaagaagac      120

uacgaccauu auuaagagcc ccugcauuag cagcuguccc aggcgguaaa ccuauccuau      180

guccaagaag gacgacagcg caauuaggac cuagaagaaa uccagcuugg agcuuacaag      240

cagguagauu auuuaguaca caaacagcag aagauaaaga agaaccucua cauagcauaa      300

ucaguaguac agaaucugua caaggaagua caaguaaaca cgaauuucaa gccgaaacaa      360

agaaacuccu ugacaucgua gcuagaaguc uauauucaga aaaagaagua uucaucaggg      420

aauuaauuuc aaaugcauca gaugccuuag aaaaacuaag acacaaacug guauccgaug      480

gacaagcccu accagaaaug gagauacauu uacaaacaaa cgcagaaaaa gguaccauca      540

caauccagga uacagguaua ggcaugacuc aagaagaacu uguuucuaac cuaggaacua      600

uagcaagauc uggcaguaaa gcauuccuag augcuuuaca aaaccaagca gaagcaucuu      660

caaaaauaau aggacaauuu gguguaggau ucuauagugc auuuauggug gcugaucgug      720

uagaaguuua uucacgguca gcagcuccag gaucauuagg auaccaaugg cuaucugaug      780

guucaggagu cuucgagauu gcagaagcau ccggaguaag aacaggcaca aaaaucauaa      840

uacaccuaaa aucugauugc aaagaauuuu cuagcgaagc aagaguaaga gauguaguca      900

caaaauacuc caacuucguc ucauucccac uauacuuaaa uggcagacga augaauacuc      960

uacaagcuau auggaugaug gauccaaaag auguccggga auggcaacau gaagaguucu     1020

auagauacgu ugcucaagcu cacgacaaac cacgauauac acuucauuac aaaaccgaug     1080

caccacuuaa uauaagauca auauuuuaug uaccagacau gaaaccaucu auguucgaug     1140

uauccagaga auuaggauca ucuguagcau uauacucaag aaaaguguua auacaaacua     1200

aagcaacaga uaucuuacca aaauggcuuc gauucauaag aggaguugua gauucagaag     1260

acaucccacu aaacuuaucg agagaauuac uacaagaauc agcacuuauu agaaaacuaa     1320

gagauguccu acaacaaaga uuaauaaaau ucuuuauaga ucaaucaaag aaagaugcag     1380

aaaaauacgc aaaauucuuc gaagacuaug gacuauuuau gagggaaggc auaguaacug     1440

caacagaaca agaaguuaaa gaagacauug caaaacuacu aagauaugaa aguuccgcgu     1500

uaccuucagg ccaacucacg agucuaagcg aauaugcaag ccgcaugcgu gcaggaacua     1560

gaaacauaua cuaccuaugu gcgccuaaca ggcaucucgc agaacauucc ccuuacuacg     1620

aagcaaugaa aaagaaagau acagaaguac ucuucugcuu cgaacaauuu gaugaacuca     1680

cauuauuaca ucuacgcgag uucgacaaaa agaaauuaau auccguagaa acagacaucg     1740

ucguagacca cuauaaagaa gaaaaauuug aagacagauc ccccgcagca gaauguuuaa     1800

gugaaaaaga aacagaagaa uuaauggcau ggaugagaaa cguacuuggc ucaagaguua     1860

cuaacguuaa aguaacucua cgacuagaca cacauccugc caugguaacg gucuuagaaa     1920

ugggagcagc aagacacuuc cuuagaaugc aacaauuagc aaaaacccaa gaagaaagag     1980

cacaauuacu acaaccaaca uuagaaauca auccuaggca ugcauuaaua aagaaacuaa     2040

accagcuuag agcaagcgaa cccggucuug cacaacuauu aguagaucaa aucuaugaaa     2100

acgccaugau agcagcaggu cuaguugacg accccagagc aaugguaggu agacuuaacg     2160

aacuacucgu caaagcauua gaaaggcauu aaggacuagu cccuguuccc agagcccacu     2220

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     2340

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              2391


<210>  7399
<211>  738
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000609.1__HsIGF1 (opt13)

<400>  7399
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaaaaauau caucacuacc uacacaacua uucaaaugcu      120

gcuucugcga cuuccuaaaa guaaaaaugc acacaauguc auccucacac cuauucuacc      180

uagcacuaug ccuacuaaca uucacaucau cagcaacagc cggaccagaa acacuaugcg      240

gagcagaacu aguagacgca uuacaauucg uaugcggaga cagaggauuc uacuucaaca      300

aaccaacagg auacggauca ucaucaagaa gagcaccaca aacaggaaua guagacgaau      360

gcuguuucag aucaugcgac uuaagaagac uagaaaugua cugcgcacca uuaaaaccag      420

caaaaagcgc aagaucagua agagcacaaa gacauacaga caugccaaaa acacaaaaag      480

aaguacaccu aaaaaacgca ucaagaggau cagcaggaaa caaaaacuac agaauguaag      540

gacuaguccc uguucccaga gcccacuuuu uuuucuuuuu uugaaauaaa auagccuguc      600

uuucagaucu aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaugcauc cccccccccc cccccccccc cccccccccc aaaggcucuu      720

uucagagcca ccagaauu                                                    738


<210>  7400
<211>  819
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000603.1__HsIGF2 (opt13)

<400>  7400
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ggaauaccaa ugggaaaauc aaugcuagua cuauuaacau      120

uucuagccuu cgcaucaugu ugcauagcag cauacagacc aagugaaacu cuauguggag      180

gagaauuagu agauacacua caauuuguau guggagauag agguuucuau uucaguagac      240

cagcaagcag aguaucaaga agaaguagag gaauaguaga agaaugcugu uucagaucau      300

gugaccuagc acuacuagaa acauauugcg caacaccagc aaaaucagaa agagauguau      360

caacaccacc aacaguauua ccagauaacu uuccaagaua cccuguagga aaauuuuucc      420

aauacgauac auggaaacaa ucaacacaaa gacuaagaag aggacuacca gcacuacuaa      480

gagcaagaag aggacacgua cuagcaaaag aacuagaagc auuuagagaa gcaaaaagac      540

auagaccauu aauagcauua ccaacacaag auccagcaca cggaggagca ccaccagaaa      600

uggcaucaaa cagaaaauaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      660

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      780

cccccccccc caaaggcucu uuucagagcc accagaauu                             819


<210>  7401
<211>  915
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000591.1__HsIL6 (opt13)

<400>  7401
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacucauuuu caacaucagc auucggacca guagcauucu      120

cacuaggauu acuacuagua cuaccagcag cauucccagc cccaguacca cccggagaag      180

acuccaaaga cguagccgcc ccacacagac aaccacuaac aucauccgaa agaauagaua      240

aacaaauaag auacauacua gacggaaucu cagcacuaag aaaagaaaca ugcaacaaau      300

caaacaugug cgaaucauca aaagaagcac uagcagaaaa caauuuaaac cuaccaaaaa      360

uggcagaaaa agacggcugc uuccaaucag gauucaauga agaaaccugc cuaguaaaaa      420

uaauaacagg auuacucgaa uucgaaguau acuuagaaua ccuacaaaac agauucgaau      480

caucagaaga acaagcaaga gcaguacaaa ugagcacaaa aguacucaua caauuccuac      540

aaaaaaaagc aaaaaaucua gacgcaauaa caacaccaga cccaacaaca aacgcaucac      600

uacuaacaaa acuacaagca caaaaccaau ggcuacaaga caugacaacu caccuaauac      660

ucagauccuu caaagaauuu cuacaauccu cacuaagagc acuaagacaa auguaaggac      720

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      780

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      900

agagccacca gaauu                                                       915


<210>  7402
<211>  1557
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002183.1__HsINHBA (opt13)

<400>  7402
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccauuacuau gguuaagagg uuuucuauua gcaucaugcu      120

ggauaauagu aagaucaagu ccaacaccag gaagugaagg ucauagugca gcaccugacu      180

guccuaguug cgcauuagca gcauuaccaa aagacguacc aaacagccag ccagaaaugg      240

uagaagcagu aaaaaaacau auauuaaaua ugcuacaucu aaaaaaaagg ccagacguaa      300

cacaaccagu accaaaagcg gcuuuauuaa augcaauaag aaaauuacau guagguaaag      360

uaggagaaaa cgguuacgua gaaauagagg augacauagg ccgaagagca gaaaugaaug      420

aacuaaugga acaaacaagu gaaauaauaa cauuugcaga aucaggaaca gcaagaaaaa      480

cgcuacacuu cgaaauaagc aaagaaggaa gcgaucuuag ugugguagaa agagcagaag      540

uaugguuauu ccugaaggua cccaaagcca aucgaacgag aacaaaagua acaauaagau      600

uauuucaaca acaaaaacau ccacaagguu cacuagauac aggagaggaa gccgaagaag      660

uagguuuaaa aggagaaaga ucugaauuau uauuguccga aaaaguagua gaugccagaa      720

aaaguaccug gcauguauuu ccagugaguu caucaauaca aagauuacua gaucaaggua      780

aaucaucacu agauguaaga auagcaugug aacaauguca agaaagugga gcuaguuuag      840

uacuauuagg aaagaaaaaa aaaaaggagg aagaaggaga aggaaaaaaa aaaggaggag      900

gagaaggagg agcgggagca gaugaagaaa aagaacaaag ucauagacca uucuuaaugu      960

uacaagcaag acaaagcgaa gaucauccac acagaagaag acgacgagga cuagaaugcg     1020

auggaaaagu caauauaugu uguaaaaaac aauuuuuugu aucauuuaaa gacauaggau     1080

ggaacgauug gauaauagcg ccaucaggau aucacgcuaa cuauugugaa ggagaauguc     1140

caagccauau agcaggaacg aguggaagcu cauuaucauu ucacagcacg guaauaaacc     1200

auuauagaau gagaggacau agcccauuug caaauuuaaa aucauguugu guaccuacaa     1260

aacuacgucc aaugagcaug cuauauuacg acgacggaca aaauauuaua aagaaagaua     1320

uccaaaauau gauaguagaa gagugcggau guagcuaagg acuagucccu guucccagag     1380

cccacuuuuu uuucuuuuuu ugaaauaaaa uagccugucu uucagaucua aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaugcaucc     1500

cccccccccc cccccccccc ccccccccca aaggcucuuu ucagagccac cagaauu        1557


<210>  7403
<211>  1500
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002184.2__HsINHBB (opt13)

<400>  7403
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gauggauuac cagggagagc auuaggagca gcaugucuau      120

uauuauuagc agcagguugg uuaggcccag aagcaugggg aucuccaaca ccaccaccaa      180

caccagcagc acccccacca ccaccaccac caggaagucc aggaggaagc caagauacau      240

guacaagcug ugguggauuu agaagaccag aagaauuagg aagaguagau ggagacuuuu      300

uagaagccgu aaaaagacac auacuuucaa gauuacaaau gagaggaagg ccaaauauaa      360

cacaugcagu accaaaggca gcaaugguua cagcauuaag aaaauuacac gcaggaaaag      420

uaagagaaga ugguagagua gaaauaccac auuuagacgg gcacgcauca ccaggugcag      480

augggcaaga aagaguaagu gagauaauua gcuuugcaga aacagaugga uuagcaucau      540

caagaguacg auuauauuuc uuuauaagua acgaaggaaa ucaaaaucua uucguagugc      600

aagcaucacu augguuauau uuaaaauuau ugccauaugu acuagaaaaa ggaagcagaa      660

gaaagguaag aguuaaaguu uauuuucaag aacaagguca uggagaucga uggaauaugg      720

uagaaaaacg aguagauuua aaaagaucag gauggcauac auuuccacua acagaagcaa      780

uacaagcauu auucgaaaga ggcgaaagaa gacugaauuu agacgugcaa ugugacucau      840

gccaagaauu agcagugguu ccagucuuug uagacccagg agaagaaagc cauagaccau      900

uuguaguagu acaagcaaga cuaggagaua guagacauag aauaagaaaa agagguuuag      960

aaugugacgg aagaacaaau uuauguugca gacaacaauu cuuuauugau uuuagguuaa     1020

uagguuggaa ugauuggaua auagcaccaa caggauauua uggaaauuau ugugaaggaa     1080

gcuguccagc auauuuagcu gguguaccag guucagcuag uaguuuucac acagcaguag     1140

ucaaucaaua ucguaugcga ggauuaaauc cugguacugu aaauagcugu uguauaccaa     1200

caaaacuaag uacaauguca auguuauauu uugaugauga auauaauaua guuaaaagag     1260

auguuccaaa uaugauagua gaagaaugug gaugcgcuua aggacuaguc ccuguuccca     1320

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1380

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1440

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1500


<210>  7404
<211>  3735
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000623.2__HsITGAM (opt13)

<400>  7404
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcauuacgag ucuuacuuuu aacagcauua acucugugcc      120

acggauuuaa ucuugauaca gaaaaugcaa ugacauuuca agaaaacgca cgaggauuug      180

gccagucggu aguacaguua caggguagca ggguuguugu cggugcccca caagaaauag      240

uagcagccaa ucaaagaggu ucacuauacc aaugugauua cucuacagga aguugugagc      300

ccauaagauu acaaguaccc gucgaagcag ucaauauguc ccuaggacua aguuuagcag      360

caacaacuag cccaccacaa uuacuagcuu gcggcccaac cguacaccag acauguucug      420

aaaauaccua ugucaaaggu uuaugcuucu uauucgguag uaauuuaaga cagcaaccac      480

aaaaauuucc ugaagcacua cgcggauguc cucaagaaga cuccgacaua gcauuucuaa      540

uagacggaag uggcaguaua auaccccaug acuuuaggag aaugaaagaa uuugugucca      600

caguaaugga acaacuaaag aaaucuaaga cacuuuucuc auuaaugcaa uauagugaag      660

aauuuagaau acauuucacc uucaaagaau uucaaaacaa cccgaaucca agaucccuag      720

uuaaaccaau aacccaguua cuaggaagaa cacauacugc cacaggcauu cgaaaaguag      780

uacgagaacu auuuaacauu acuaauggag cuagaaagaa cgcuuucaaa auucuaguag      840

uuauaacuga uggagagaaa uucggagacc cucuuggaua cgaagauguu auaccagaag      900

ccgauagaga aggagucaua agauauguaa uaggaguagg cgaugccuuc cgaagcgaaa      960

aauccagaca ggaacuaaau acaauagcua gcaaaccacc gagggaccac guuuuucaag     1020

ucaauaauuu ugaagcauua aaaaccauuc aaaaccaacu aagggagaaa auauucgcua     1080

uagaaggaac acaaaccgga ucuaguagua gcuuugaaca ugaaaugucc caagaagguu     1140

uuucugcugc gauaacuuca aauggcccac uacuaucaac agucgguagu uaugauuggg     1200

ccggaggagu auuccuuuau acaaguaaag aaaaaucaac auucauaaau augacaagag     1260

uagacucuga uaugaaugau gccuauuuag gauacgcagc agcaaucaua cuacgcaaca     1320

gaguccaauc acucguacua ggugccccca gauaccaaca uaucggucug gucgcuaugu     1380

uucgucaaaa uacagguaug ugggaaagua augcaaaugu aaaagguacu caaauaggcg     1440

cauauuuugg ugcuucauua ugcagcguug acguggauuc gaacgguagu acagacuuag     1500

uguuaauagg cgcaccccac uacuacgaac aaacaagagg ugggcaggua ucaguaugcc     1560

cucuacccag aggccgugcc agauggcaau gugacgcagu acuauaugga gaacaagggc     1620

aaccaugggg uagauuuggg gcugcauuga caguuuuagg agacguaaau ggagauaaac     1680

uaacggaugu ugcuauagga gccccuggug aggaagauaa uagaggagcg guauaccuau     1740

uucauggaac aucuggaagu ggaauuucac cuagucacuc acaaaggaua gcaggaucca     1800

agcucucccc acgauuacaa uauuuuggac agagccuauc gggaggucaa gaucuaacua     1860

uggaugguuu gguggaucuc accguaggcg cucaagguca ugugcuacua uuacgaucac     1920

aaccuguacu uagaguaaaa gccauaaugg aguucaaccc aagagaagua gcucguaaug     1980

uauucgaaug caacgaucaa guuguaaaag gcaaagaagc aggagaagug cgugucuguc     2040

uucauguuca gaaaagcaca cgugaucgau uaagagaggg ccaaauucaa ucuguaguua     2100

cauacgacuu agccuuagac uccggacgac cacacucucg cgcagucuuu aaugaaacga     2160

aaaacucaac acgaaggcaa acacaaguac uaggauuaac ucaaacaugc gaaacccuua     2220

aacuacaauu accuaacugu aucgaagacc caguaucucc aaucguauug agacuaaauu     2280

uuuccuuagu aggcacacca cuuagugcuu uuggaaaucu aagaccgguc uuagcagaag     2340

augcucaaag auuauuuacc gcacuguucc cauucgagaa aaacugugga aacgauaaua     2400

uaugccaaga cgacuuaucu auuacauucu cauucauguc guuagauugu cuaguaguag     2460

gaggacccag agaauuuaau guaaccguca caguucgaaa ugacggagaa gacucauaua     2520

gaacccaagu aacauucuuc uuuccguuag aucucagcua ucggaaagua ucaacauuac     2580

aaaaccaacg aagccaacga ucauggaggc ucgcauguga aagcgcuucc aguacggaag     2640

uaaguggagc acucaaaucu acaucuugcu cuauuaacca cccaauauuu ccggaaaaca     2700

gugaggucac uuuuaauauc accuucgacg uagauagcaa agccaguuua ggaaauaaac     2760

uucuucucaa ggcaaacgua acuucugaaa auaauaugcc aagaaccaac aaaacagagu     2820

uccaacuaga auuaccaguc aaauacgcag uauauauggu aguaacaagu cauggaguuu     2880

ccacgaaaua ccuaaacuuu acugcaucag aaaacacaag cagaguaaug caacaucaau     2940

accaaguauc aaauuuagga caacgaaguu uaccaauauc guuaguuuuc cuggucccag     3000

ucagauugaa ucaaacagua aucugggaua gaccacaagu aacauuuuca gaaaaucucu     3060

caucaaccug ucauaccaag gaaagauuac cuucacauuc agauuuucua gcagaacuac     3120

gcaaagcucc aguaguuaau ugcucaaucg caguauguca aagaauacaa ugugacaucc     3180

cauucuuugg cauucaagaa gaauuuaacg cuacauuaaa aggaaaucuu aguuuugauu     3240

gguacaucaa aaccagucau aaccauuuac uaauagucuc uacugcugaa auacuauuua     3300

augauucugu auuuacucua uuaccaggac aaggagcuuu uguucgauca caaacagaaa     3360

cuaaaguaga accauucgaa gucccaaauc cauuaccauu aaucgugggu ucuucuguag     3420

gcggcuuauu acuuuuagca uuaauaacug cugccuugua uaaauuagga uuuuucaaaa     3480

ggcaauauaa agauaugaug ucugaaggag guccacccgg agccgaacca caauaaggac     3540

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     3600

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     3660

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     3720

agagccacca gaauu                                                      3735


<210>  7405
<211>  1680
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002415.1__HsMMP8 (opt13)

<400>  7405
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uucucccuca aaacacuacc auucuuacua cuacuccaug      120

uacaaauauc caaagcauuc ccuguaucau caaaagaaaa aaacacaaaa acaguacaag      180

acuaccuaga aaaauucuac caauuaccuu caaaccaaua ccaaucaaca agaaaaaacg      240

gaacaaacgu uauaguagaa aaacuaaaag aaaugcaacg uuucuuuggu uuaaauguaa      300

cagguaaacc aaacgaagaa acauuagaca ugaugaaaaa accaagaugu ggaguaccag      360

acuccggcgg auuuauguua acaccaggaa auccaaaaug ggaaagaaca aauuuaacuu      420

accgaauaag aaacuacaca ccucaauuaa gcgaagcaga aguagaaaga gcaauaaaag      480

augccuucga acuauggucc guagcaucac cucuaauuuu cacaagaaua ucacaaggag      540

aagcagacau caacauagcu uuuuaucaaa gagaucacgg agacaauuca ccauuugaug      600

gaccaaacgg aauccuagca caugcauuuc aacccgguca aggaauagga ggagacgcac      660

acuucgaugc cgaagaaaca uggaccaaca cuucagcaaa cuacaaccua uuucuaguag      720

cagcacauga auucggccac ucauuaggac ucgcucauuc cucagacccu ggagcccuaa      780

uguaucccaa cuaugcauuc agagaaacau caaacuauuc acuaccucaa gacgacauag      840

auggaauuca agcuaucuac ggauuaucau caaacccaau ucaaccaaca ggaccaucaa      900

cacccaaacc uugugaccca ucccuaacau uugacgcuau aacaacacua agaggagaaa      960

uauuauucuu caaagacaga uacuuuugga gaagacaccc ucaacuacaa agaguugaaa     1020

ugaacuuuau aucauuauuc uggccaucac uaccaacagg aauacaagca gcauacgaag     1080

acuucgauag agacuuaaua uuccuuuuca aaggaaacca auacugggcc cuaaguggau     1140

acgacauauu acaagguuau ccuaaagaca uaucaaacua cggauuucca ucuucaguac     1200

aagcaauaga cgcagcaguc uucuauagau caaaaacaua cuuuuucgua aacgaccaau     1260

ucuggagaua ugacaaccaa cgacaauuua uggaaccagg auauccaaaa ucaauaucag     1320

gagcauuccc uggaauagaa uccaaaguag acgcaguauu ucaacaagaa cacuucuucc     1380

auguuuuuuc aggaccaaga uacuacgcuu uugacuuaau agcacaaaga guaacaagag     1440

uagcaagagg aaacaaaugg cuaaacugcc gauauggaua aggacuaguc ccuguuccca     1500

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     1620

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     1680


<210>  7406
<211>  2400
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004985.2__HsMMP9 (opt13)

<400>  7406
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucauuauggc aaccauuagu uuugguacuu uuaguauuag      120

gauguuguuu ugcugcacca cgucaaagac aaaguacauu aguccuauuu ccaggcgauu      180

uaagaacaaa uuuaacagac agacaacuug cagaagaaua ucuauauaga uaugguuaua      240

caagaguagc ugaaaugaga ggugaaucaa aaucucuagg accagcauua uuacuacuac      300

aaaaacaguu aucacuacca gaaaccgggg aacuagacuc agcuacacuu aaagcaauga      360

gaacuccacg guguggaguc ccagaucucg gucgguuuca aacauuugaa ggagaccuua      420

aauggcauca ucacaauaua acauauugga uacagaauua uucagaagac cuaccaagag      480

cgguuauaga cgacgcauuc gcccgagcau uugcacuaug gagugcugua acaccauuga      540

cuuuuacaag gguauauagu cgagaugcag auaucguaau acaauuuggu guagcagagc      600

auggggaugg auacccuuuu gacgguaaag acggacuucu agcacaugca uuuccaccag      660

gaccuggaau acaaggagau gcccauuuug augacgacga acuauggagu cuuggaaaag      720

gagucguagu accuacaaga uuugguaaug cugauggugc agcaugucau uuuccuuuua      780

uauuugaagg acgaucuuac ucugcaugca cuacagaugg acguucagau ggauuaccau      840

gguguucuac uacagccaau uaugauacag augauagauu ugguuuuugu ccuucagaac      900

gauuauauac gcaagaugga aaugcagaug gaaaaccuug ucaauuccca uuuauauuuc      960

aaggacaauc auauucagca uguacaacag auggacgaag cgauggauau cgauggugug     1020

caacaacagc uaacuacgac agagauaaau uauuugguuu uuguccaacu cgcgcugacu     1080

caacagucau gggugguaau agcgcuggug aauuaugugu auuuccauuu acuuuccuug     1140

gcaaagaaua cucaacaugc acaucggaag gaagaggaga uggacgauua uggugugcaa     1200

cuacuaguaa uuucgacagu gacaaaaaau ggggauuuug uccggaccaa ggguauucac     1260

uuuucuuagu ugcagcacac gaauucgguc augcacuugg ccuagaccau ucaucaguac     1320

cugaagcucu uauguaccca auguauagau uuacagaagg accuccacuc cauaaagacg     1380

augucaacgg cauacgccau cuauaugguc cacguccaga gccugaacca aggccuccca     1440

caacaacaac accacaaccu acugcuccac cuacaguaug cccgacuggc ccaccaacag     1500

uacauccauc ugaaagacca acggccggac caacgggacc uccuucagcg gguccaacag     1560

gaccaccaac agcaggcccc agcacugcca cuacaguacc auuaucaccu guggacgaug     1620

cuuguaaugu uaauauauuu gaugcaauag cugaaauugg uaaucaacug uauuuauuua     1680

aagauggaaa auauuggcga uuuagugaag gacgcggauc uagaccccaa ggaccauuuc     1740

uaauugccga uaaauggcca gcccuaccua gaaaauuaga uucuguauuu gaagaaagau     1800

uaucaaaaaa auuauuuuuu uucucaggaa gacaaguaug gguuuauaca ggagcaucag     1860

uacuaggacc uagaagacua gauaaacuag guuuaggagc cgacgucgca caaguuacag     1920

gcgcccuaag aucaggaaga ggaaaaaugu uauuauucag cgguagaaga uuauggagau     1980

uugaugugaa agcacaaaug guugauccaa gaucagcuag cgaagucgau cgaauguucc     2040

cagguguacc auuggauacu caugauguuu uucaauauag agaaaaagca uauuuuuguc     2100

aagauagauu uuauuggcgu guuucaucua ggagugaauu aaaccaagug gaucaaguag     2160

gauauguaac auacgauaua cuacaauguc cagaagauua aggacuaguc ccuguuccca     2220

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa     2280

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca     2340

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu     2400


<210>  7407
<211>  1692
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002418.1__HsMMP13 (opt13)

<400>  7407
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacccaggag uauuagcagc auuccucuuc uuaucaugga      120

cacacugccg agcauuacca uuaccaucag gaggagacga agacgaucua ucagaagaag      180

accuucaauu cgcagaaaga uacuuaagau cauacuacca cccaacaaac uuagcaggua      240

uacuaaaaga aaacgcagcc ucuucaauga cagaaagacu uagagaaaug caaucauucu      300

ucggauuaga aguaacagga aaauuagaug acaauacacu agauguaaug aaaaaaccua      360

gaugcggagu uccugacgua ggagaauaua acgucuuucc aagaacauua aaauggucca      420

aaaugaaccu aacauauaga auaguaaacu auacaccaga uaugacccau ucagaagucg      480

aaaaagcauu caaaaaagca uucaaaguau ggucagaugu aacaccucua aacuucacaa      540

gacuacauga cggaauagca gacaucauga uaagcuuugg aauaaaagaa cacggagauu      600

ucuacccauu cgacggacca ucuggauuau uagcccacgc auuuccccca ggaccaaauu      660

auggaggaga cgcacauuuc gaugacgaug aaacauggac aucaucauca aaaggauaca      720

accuauucuu aguagcagca cacgaauucg gacacucuuu aggcuuagac cauucaaaag      780

accccggagc acuaauguuc ccaauauaua cauauacagg aaaaagccac uucauguuac      840

cagacgauga cguccaaggu auacaaaguc uauacggacc aggagaugaa gauccuaacc      900

caaaacaucc aaaaacccca gacaaaugug auccaucauu aucauuagau gccauaacau      960

cauuacgagg agaaacaaug auuuucaaag accguuucuu cuggcgucuu cacccacaac     1020

aagucgacgc agaacucuuu uuaacaaaau cguuuuggcc ugaacuacca aacagaauag     1080

augcagcaua cgaacacccu agucacgacu uaauauuuau uuuucgagga cgaaaauucu     1140

gggcccuaaa uggauacgau auauuagaag gauacccuaa aaaaauaucu gaacuaggau     1200

uaccaaaaga aguaaaaaaa auaucagccg caguccacuu ugaagauaca ggaaaaacac     1260

uucuauuuuc aggcaaucaa gucuggagau acgacgacac aaaccacaua auggacaaag     1320

acuaccccag auuaauagaa gaagacuucc caggcauagg ugacaaagua gacgcaguau     1380

acgaaaaaaa cggauauaua uauuucuuca acggaccaau acaauuugaa uacucuauau     1440

ggucaaacag aauaguaaga guaaugccag caaacuccau uuuauggugc uaaggacuag     1500

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag     1560

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1620

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga     1680

gccaccagaa uu                                                         1692


<210>  7408
<211>  1344
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001286.1__HsCCR1 (opt13)

<400>  7408
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gaaacaccaa acacaacaga agacuacgau acaaccacag      120

aauuugauua uggagacgca acaccauguc aaaaaguaaa cgaaagagcc uuuggcgcgc      180

aacuacuacc cccauuauac ucacuagucu ucgucauagg acuaguaggu aauauacuag      240

uaguacuagu auuaguccaa uacaaaagau uaaaaaauau gacaucaaua uauuuacuaa      300

acuuagcaau aucagauuua cuauuccuau ucacauuacc auucuggauc gacuacaaac      360

uaaaagacga cuggguauuu ggagacgcaa ugugcaaaau acucucagga uucuacuaca      420

caggccuaua cucugaaauc uucuucauaa uacuacuaac aauagauaga uaccuagcaa      480

uaguucaugc aguauucgca uuaagagcca gaaccgucac auucggaguc auaacaucaa      540

uaauaauaug ggccuuagca auauuagcau caaugccagg acuauacuuu ucuaaaacac      600

aaugggaauu cacacaucau acaugcucac uucacuuccc ucacgaaucc cuaagagaau      660

ggaaacucuu ccaagcauua aaacucaauc uuuucggacu aguacuaccc cuacucguaa      720

ugaucauaug cuacacagga auaauaaaaa uacuacuacg acgaccaaac gaaaaaaaau      780

caaaagcagu aagauuaaua uucguaauaa ugaucaucuu cuuccuuuuu uggaccccuu      840

acaaccucac aauacuaaua ucaguauucc aagacuuuuu auucacacac gaaugugaac      900

aauccagaca ucucgacuua gcaguacaag ucaccgaagu aauagcauac acacacuguu      960

gcguuaaccc cguaauauac gcuuuuguag gagaaagauu ccgaaaauau cuaagacaac     1020

uauuucacag acgaguugca guacacuuag ucaaaugguu accauuucua ucaguagaua     1080

gauuagaaag agucucaucc acaucaccau caaccggaga acacgaauua ucagcaggau     1140

ucuaaggacu agucccuguu cccagagccc acuuuuuuuu cuuuuuuuga aauaaaauag     1200

ccugucuuuc agaucuaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa ugcauccccc cccccccccc cccccccccc ccccccaaag     1320

gcucuuuuca gagccaccag aauu                                            1344


<210>  7409
<211>  912
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002598.4__HsPDGFA (opt13)

<400>  7409
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug agaacacuag caugccuacu auuacuagga ugcggauacc      120

uagcacaugu acuagcugaa gaagcagaaa uaccaagaga aguaauagaa agacuagcaa      180

gaucacaaau acacucaaua agagaccuac aacgacuacu agaaauagac ucagucggaa      240

gugaagacuc acucgacaca agucuaagag cacacggagu acacgcaaca aaacacguac      300

cagaaaaaag accacuaccc auaagaagaa aaagaagcau agaagaagca guaccagcag      360

uaugcaaaac acgaacagua auauacgaaa uaccaagauc acaaguagac ccaacaucag      420

caaacuuccu aauauggccc ccaugcguag aaguaaaaag augcacagga ugcugcaaca      480

caucaagcgu aaaaugccaa ccaagcaggg uacaccacag aagcgucaaa guagcaaaag      540

uagaauacgu aagaaaaaaa ccaaaacuaa aagaaguaca aguaagacua gaagaacacc      600

uagaaugcgc augugcaaca acaagccuaa auccagauua cagagaagaa gacacaggaa      660

gaccaagaga aagcggaaaa aaaagaaaaa gaaaaagacu aaaaccaaca uaaggacuag      720

ucccuguucc cagagcccac uuuuuuuucu uuuuuugaaa uaaaauagcc ugucuuucag      780

aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      840

aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc ucuuuucaga      900

gccaccagaa uu                                                          912


<210>  7410
<211>  1002
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002599.1__HsPDGFB (opt13)

<400>  7410
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacagaugcu gggcauuauu cuuaucauua ugcuguuacc      120

uaagauuagu aucagcagaa ggagauccaa uaccagaaga acuauacgaa augcuaagcg      180

aucacaguau aagaagcuuu gacgaucuac aaagauuacu ucacggcgau ccaggagaag      240

aagacggagc agaauuagac cuaaauauga caagaucaca cucaggagga gaauuagaau      300

cacuagcacg uggaagaaga agccuaggaa gucuaacaau agcagaaccu gcaaugauag      360

cagaauguaa aacacgaaca gaaguauucg aaauaucaag aagauuaaua gauagaacaa      420

augcaaauuu cuuaguaugg ccaccaugug uagaaguaca aagaugcagu ggaugcugca      480

auaacagaaa cguacaaugu agaccaacac aaguacaauu aagaccagua caaguaagaa      540

aaauagaaau aguaagaaaa aaaccaauau uuaaaaaagc aacagucaca uuagaggacc      600

accucgcaug caaaugugaa accguagcag cagcaagacc aguaacaaga agcccaggcg      660

gaagccaaga acaaagagca aaaacaccac aaacuagagu uacaauaaga acaguaagag      720

uacgaaggcc cccaaaagga aaacauagaa aauucaaaca cacacacgac aaaacagcac      780

uaaaagaaac acuaggagcg uaaggacuag ucccuguucc cagagcccac uuuuuuuucu      840

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc      960

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1002


<210>  7411
<211>  1314
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_057289.1__HsPDGFC (opt13)

<400>  7411
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucauuauuug gauuauuacu acuuacauca gcauuagcag      120

gacaaagaca agguacacaa gcagaaagca aucuaucaag caaauuccaa uuuucaucca      180

auaaagaaca aaauggagua caagacccac aacacgaaag aauaauaacc gucagcacaa      240

acggcucaau acauagucca cgauucccac auacauaucc aagaaacacc guacucgucu      300

ggagauuagu agcaguugaa gaaaauguau ggauccaauu aacauucgac gaaagauuug      360

gauuagaaga cccugaagac gacauaugca aauacgacuu uguagaagua gaagaaccau      420

cagacggaac aauauuagga cgauggugcg gaucagguac aguaccuggu aaacaaaucu      480

caaaaggcaa ccaaauaaga auaagauucg uaagcgauga auacuuccca agugaaccag      540

gauucuguau acauuacaau aucgucaugc cacaauucac agaagcagua ucaccaucag      600

uacuaccacc aucagcucua ccauuagacu uacuaaauaa cgcuauaaca gcauuuucaa      660

cauuagaaga cuuaauacga uacuuagaac cagaaagaug gcaacuagac cuagaagacc      720

uauacaggcc aacauggcaa cuucuaggaa aagcauuugu auuuggaaga aaaucacgag      780

uugucgaucu aaaccuauua acagaagaag uaagacuuua cucaugcaca ccaagaaacu      840

uuucaguauc cauaagagaa gaacuaaaaa gaacagauac aauauucugg ccaggaugcc      900

uacuaguaaa aagaugcggc ggaaauugcg caugcugcuu acacaacugu aacgaaugcc      960

aaugcguacc aucaaaaguu acaaaaaaau accacgaagu acuacaauua agacccaaaa     1020

cuggaguuag aggacuacau aaaucucuaa cagacguagc acuagaacau cacgaagaau     1080

gugacugcgu uugccgagga agcacaggag gcuaaggacu agucccuguu cccagagccc     1140

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa     1200

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc     1260

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu           1314


<210>  7412
<211>  1371
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_149126.1__HsPDGFD (opt13)

<400>  7412
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacagauuaa uauuuguaua cacacuaaua ugugcaaacu      120

ucugcucaug cagagacaca uccgcaacuc cacaaucagc aucaauaaaa gcuuuaagaa      180

acgcaaaucu aagaagagac gaucuauaca gaagagacga aaccauacaa guaaaaggaa      240

acggcuacgu acaaagccca cgauucccua acucauaccc aagaaaucua uuauuaacau      300

ggcgacuaca cucccaagaa aacacaagaa uacaacuagu auucgauaac caauucggau      360

uagaagaagc agaaaacgac auauguagau augauuucgu agaaguagaa gacauaucag      420

aaacaucaac uauaauacga ggaagauggu gcggacacaa agaaguacca ccacgaauaa      480

aaucaagaac aaaccaaaua aaaauaacuu ucaaaucaga ugacuacuuc guugcaaaac      540

ccggauucaa aauauauuau agccuacuag aagacuucca accagcagca gcuucagaaa      600

caaauuggga aucagucaca agcucaauau caggaguauc auauaauagc ccaucaguua      660

cagacccaac acuaaucgcc gacgcauuag acaaaaaaau agcagaauuc gauacaguag      720

aagaucuacu aaaauacuuu aacccugaau cauggcaaga agaucuagaa aacauguauc      780

uagacacacc cagauacaga ggaagaagcu accacgacag aaaaucaaaa guagacuuag      840

acagacuaaa ugaugacgca aaaagauacu caugcacacc aagaaacuac agcguaaaua      900

uaagagaaga acuaaaauua gcaaacguag uauucuuccc aagaugucua uuaguacaac      960

gcugcggagg aaacugugga ugcggaacag uaaacuggcg aagcuguaca ugcaauuccg     1020

gaaaaacagu caaaaaauac cacgaaguac uacaauucga acccggacau auaaaaagaa     1080

gagguagagc aaaaacaaug gcacuaguag auauacaauu agaccaccau gaaagaugcg     1140

auuguauaug cagcucuaga ccuccaagau aaggacuagu cccuguuccc agagcccacu     1200

uuuuuuucuu uuuuugaaau aaaauagccu gucuuucaga ucuaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaugc aucccccccc     1320

cccccccccc cccccccccc cccaaaggcu cuuuucagag ccaccagaau u              1371


<210>  7413
<211>  954
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003946.3__HsSOCS3 (opt13)

<400>  7413
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gucacccauu caaaauuccc agcagcagga augucaagac      120

cauuagacac aucauuacga uuaaaaacau ucucaucaaa aucagaauac caacuaguag      180

uaaaugcagu aagaaaacua caagaaucag gauucuauug gucagcagua acaggaggag      240

aagcaaauuu auuacuauca gcagaaccag caggaacuuu ccuaauacga gacucaucag      300

accaacgaca cuucuuuacu cuaucaguaa aaacacaauc aggaacaaaa aaccucagaa      360

uacaauguga aggaggauca uucucccuac aaucagaccc cagaucaaca caacccguac      420

caagauucga cugcguacua aaacuaguac accacuacau gccaccaccc ggagcaccau      480

ccuucccauc uccaccaaca gaaccaucau cugaaguacc ugaacaacca ucagcacaac      540

cacuaccugg aucaccacca agaagagcau acuacauaua cucaggagga gaaaaaauac      600

cacuaguacu uucaagacca cuaucaucua auguagcaac acuacaacac uuaugccgaa      660

aaacaguaaa cggccaccua gacucauacg aaaaagucac acaacuacca ggaccaauaa      720

gagaauucuu agaucaauac gacgcaccac uauaaggacu agucccuguu cccagagccc      780

acuuuuuuuu cuuuuuuuga aauaaaauag ccugucuuuc agaucuaaaa aaaaaaaaaa      840

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa ugcauccccc      900

cccccccccc cccccccccc ccccccaaag gcucuuuuca gagccaccag aauu            954


<210>  7414
<211>  759
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003227.1__HsTGFA (opt13)

<400>  7414
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug guaccaucag caggacaauu agcauuauuu gcacuaggaa      120

uaguacuagc agcaugucaa gcauuagaaa acucaacauc accacuauca gcagacccac      180

caguagcagc agcaguagua ucacauuuua augauugccc agacucacac acacaauucu      240

gcuuucacgg aacauguaga uuucuaguac aagaagacaa accagcaugu guaugucauu      300

caggauaugu aggagcaaga ugugaacaug cagauuuauu agcaguagua gcagcaucac      360

aaaaaaaaca agcaauaacu gcauuaguag uaguaaguau aguagcauua gcaguauuaa      420

uaauaacaug uguauuaaua cauugcuguc aaguaagaaa acauugugaa uggugcagag      480

cauuaauaug uagacaugaa aaaccuucag cauuacuaaa aggaagaaca gcaugcuguc      540

acucagaaac aguaguauaa ggacuagucc cuguucccag agcccacuuu uuuuucuuuu      600

uuugaaauaa aauagccugu cuuucagauc uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      660

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaugcau cccccccccc cccccccccc      720

cccccccccc caaaggcucu uuucagagcc accagaauu                             759


<210>  7415
<211>  1449
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_000651.3__HsTGFB1 (opt13)

<400>  7415
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaccaucag gucuacgacu acuaccucuc uuacuaccuu      120

uacuauggcu ccucguacua accccaggcc gaccagcagc uggccuauca acaugcaaaa      180

caauagacau ggaauuaguc aaaagaaaaa gaauagaagc aauuagagga caaauacuau      240

caaaauuaag auuagccucc ccaccuucuc aaggagaagu accaccaggu ccacuaccug      300

aagcaguccu agcacuauac aacucaacaa gagacagagu agcaggagaa uccgcagaac      360

cagaacccga accagaagca gacuauuaug caaaagaagu caccagagua cuaaugguag      420

aaacacauaa ugaaaucuac gauaaauuua aacaaucaac acauucaaua uacauguuuu      480

ucaacacaag ugaacuaaga gaagcaguac cagaaccagu auuacuauca cgagccgaau      540

uaagacuccu aagacuuaaa cuaaaaguag aacaacacgu ugaauuauac caaaaauacu      600

cuaacaacuc auggagauac uuaucuaauc gacuacuagc acccucagac ucaccagaau      660

ggcucucauu cgacguaacc ggaguaguac gacaauggcu aucccguggc ggugaaauag      720

aaggauucag acuauccgca cacugcucuu gcgacucaag agacaauaca uuacaaguag      780

auauaaacgg auucacaaca ggaagaagag gagacuuagc uacaauccac ggaaugaacc      840

gccccuuccu acuauuaaug gcaacuccuc uagaaagagc acaacacuua caauccucaa      900

gacacagaag agcacuagac acaaacuauu guuucucaag cacugaaaaa aacugcugcg      960

uccgacaauu auacauagac uuccgaaaag aucucggaug gaaauggaua cacgaaccaa     1020

aaggauacca cgccaacuuc ugccucgguc cauguccaua uaucugguca cuagauacac     1080

aauacuccaa aguacuagca uuauauaacc aacauaaucc aggagcauca gcagcgccau     1140

gcugcguacc acaagcauua gaaccacucc caauaguaua cuaugucgga agaaaaccaa     1200

aaguagaaca acuaucaaac augauaguca gaucaugcaa auguucuuaa ggacuagucc     1260

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc     1320

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1380

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc     1440

accagaauu                                                             1449


<210>  7416
<211>  1521
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003229.1__HsTGFB2 (opt13)

<400>  7416
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug cacuauugcg uacuuucagc auuucuaaua uuacaccuag      120

uaacagucgc uuuaaguuua agcacaugcu caaccuuaga cauggaccaa uuuaugagaa      180

aacgaauaga agcaauaaga ggacaaauau uauccaaacu aaaacuaaca ucaccacccg      240

aagauuaucc agaaccagaa gaagucccac cagaaguaau aucaauauau aacagcacaa      300

gagaccuccu acaagaaaaa gcaucaagaa gagcagcagc augcgaacga gaaagaucag      360

augaagaaua uuacgcuaaa gaaguauaca aaauagacau gccccccuuc uuuccaucag      420

aaaaugcaau accaccaacc uuuuacagac ccuauuuucg aauaguaaga uucgauguau      480

cagccaugga aaaaaacgca ucaaaccuag ucaaagcgga auucagagua uuccgacuuc      540

aaaacccaaa agcuagaguu cccgaacaac gaaucgaacu auaucaaaua cuaaaaucaa      600

aagaccuaac cucacccaca caaagauaca uagacucaaa aguaguaaaa accagagcag      660

agggcgaaug guuaucauuc gacguaacag acgcaguaca cgaauggcua caucacaaag      720

accgaaaucu cggauucaaa auaucacuac acugcccaug cugcacauuc gucccaucaa      780

acaacuauau aauaccaaau aaaucagaag aacuugaagc aagauuugcu ggaauagacg      840

gaacaaguac auacaccucu ggagaccaaa aaacuauaaa aucaacaaga aaaaaaaacu      900

cuggcaaaac accucaccua cuauuaaugc uacuacccuc auacagacua gaaucacaac      960

aaacaaaccg aagaaaaaaa agagcacuag acgcagcaua cuguuucaga aacguacaag     1020

auaacugcug ccucagacca cuauauauag acuucaaaag agaccuagga uggaaaugga     1080

uacaugaacc aaaaggcuac aacgccaacu ucugcgcagg agcaugccca uacuuauggu     1140

caucugacac acagcacuca agaguacuau cacuauacaa cacaauaaau ccagaagcuu     1200

cagcaagucc cugcugcgua ucacaagacu uagaacccuu aacuauauua uauuauaucg     1260

gaaaaacacc aaaaauagaa caacuaucaa acaugauagu aaaaucaugu aaauguaguu     1320

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1380

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1500

cuuuucagag ccaccagaau u                                               1521


<210>  7417
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003230.1__HsTGFB3 (opt13)

<400>  7417
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aaaaugcacc uccaaagagc ccucgucguu cucgcacuac      120

uaaacuucgc aaccguauca cuaucccuau caacaugcac aacccuagac uucggacaca      180

uaaaaaaaaa aagaguagaa gcaauccgag gccaaauuuu aucaaaacua agacuaacau      240

caccaccaga acccacaguc augacacacg uaccauacca aguccuagca cuauacaacu      300

caacacgaga acuauuagaa gaaaugcacg gagaaagaga agaaggaugu acacaagaaa      360

acacugaaag ugaauacuau gcaaaagaaa uacacaaauu cgauaugaua caaggacuag      420

cagaacacaa cgaacuagca guaugcccaa aaggaauaac aucaaaagua uuucgauuca      480

acguaucauc aguagagaaa aaucgaacaa accuauuuag agccgaauuu agaguccuaa      540

gaguccccaa uccaucauca aaaagaaacg aacaacgcau agaacuauuu caaauacuac      600

gcccagacga acacauagca aaacaaagau acauaggugg aaaaaaccuc ccaaccagag      660

gaacagccga auggcuauca uucgacguaa cagacaccgu cagagaaugg cuacuccgca      720

gagaaucaaa cuuaggucua gaaauaucaa uacacugccc augccauaca uuucaaccaa      780

auggagacau auuagaaaac auacaugaag uaauggaaau caaauucaaa ggaguagaca      840

acgaagacga ccacggacga ggcgaccucg gcagacuaaa aaaacaaaaa gaucaccaca      900

auccacaccu aauccuaaug augauacccc cccacagacu agacaaccca ggacaaggag      960

gacaacgaaa aaaaagagca cucgacacaa auuauuguuu ccgaaaucua gaagaaaacu     1020

gcugcguccg uccacuuuac auagacuuca gacaagaccu aggauggaaa uggguucacg     1080

aaccaaaagg auauuaugcc aacuucugcu caggacccug cccauacuua agaucagcag     1140

acacaacaca cucuacagua cuaggacuau acaacacacu aaacccagaa gccucagcau     1200

cacccugcug ugucccacaa gaccuagaac cuuuaaccau acuauacuac guaggaagaa     1260

cuccuaaagu agaacaacuu ucaaauaugg uaguaaaauc augcaaaugc ucauaaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  7418
<211>  1662
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001057.1__HsTNFRSF1B (opt13)

<400>  7418
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug gcaccaguag caguaugggc agcacuugca guaggacucg      120

aauuaugggc agcagcacau gcauuaccug cacaaguugc auucacaccc uacgcacccg      180

aaccaggcuc aaccuguaga uuaagagaau auuacgauca aacagcucaa augugcuguu      240

cuaaaugcuc accuggccaa caugcaaaag uauuuugcac uaaaacaucu gauaccguau      300

gugauucuug ugaagacuca acauauacac aacuauggaa cuggguucca gaaugucuau      360

caugcggauc aagauguuca ucagaccaag uugaaacaca agcauguacu cgugaacaaa      420

aucgaauuug cacauguaga ccaggauggu auugcgcuuu aucgaaacaa gaaggaugua      480

gacuaugcgc accucuuaga aaaugcagac caggcuuugg agucgcucga cccggaacug      540

aaacaucaga cguaguaugc aaaccuugug caccagguac auucucuaac acaacaaguu      600

caacagauau uuguagacca caccaaauau guaacguagu ugcuauacca ggaaacgcau      660

cuauggaugc aguauguaca ucuacgucac cuaccagauc aauggcacca ggagcaguuc      720

acuuaccaca accaguauca acaagaaguc aacacacaca accaacaccu gaacccucaa      780

cugcaccaag cacuucauuu cuacuaccaa ugggucccuc accaccugcu gaaggaucaa      840

caggagacuu cgcauuaccu gucggacuua ucguaggagu uacagcauua ggacuauuaa      900

uaaucggugu aguaaauugu guuauuauga cacaaguaaa aaaaaaaccc uuauguuuac      960

aaagagaagc caaaguaccu cauuuaccag cagauaaagc cagaggaacc caagguccag     1020

aacaacaaca uuuauuaauc acagcucccu caucaucauc aucaucuuua gaaucaucag     1080

caagugcucu agauagaaga gcucccacaa gaaaccaacc ucaagcacca ggugucgaag     1140

caucaggagc uggugaagcu cgugcuucua cgggaucuuc agauucauca cccggaggac     1200

acggaacaca aguaaaugua acaugcauag uaaaugucug uuccaguucg gaucauucau     1260

cacaauguuc aucacaagca ucaucuacua ugggagauac agauaguuca ccaucagaau     1320

ccccaaaaga cgaacaagua ccauuuucaa aagaagaaug cgcauuuaga ucacaauuag     1380

aaacaccaga aacauuauua ggaucaacug aagaaaaacc acuaccacua ggcguaccag     1440

augcaggaau gaaacccuca uaaggacuag ucccuguucc cagagcccac uuuuuuuucu     1500

uuuuuugaaa uaaaauagcc ugucuuucag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa     1560

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc     1620

cccccccccc ccccaaaggc ucuuuucaga gccaccagaa uu                        1662


<210>  7419
<211>  789
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_002623.2__HsPGF (opt13)

<400>  7419
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ccaguaauga gauuauuucc auguuucuua caauuauuag      120

caggauuagc auuaccagca guaccaccac aacaaugggc guuaucagca ggaaauggaa      180

guagugaagu agaaguagua ccauuucaag aaguaugggg aagaucauau uguagagcac      240

uagaaagacu aguagaugua guaagugaau auccaagcga aguagaacau auguuuucac      300

caucaugugu aaguuuauua agauguacgg gaugcugugg agaugaaaau uuacauugug      360

uaccaguaga aacagcaaau guaacaaugc aauuauuaaa aauaagaagu ggagauagac      420

caucauaugu agaauuaaca uuuagccaac auguaagaug ugaauguaga ccauuaagag      480

aaaaaaugaa accagaaaga agaagaccaa aaggaagagg aaaaagaaga agagaaaaac      540

aaagaccaac agauugucau uuauguggag augcaguacc aagaagauaa ggacuagucc      600

cuguucccag agcccacuuu uuuuucuuuu uuugaaauaa aauagccugu cuuucagauc      660

uaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      720

aaaaaugcau cccccccccc cccccccccc cccccccccc caaaggcucu uuucagagcc      780

accagaauu                                                              789


<210>  7420
<211>  1515
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001020537.2__HsVEGFA (opt13)

<400>  7420
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug acagauagac aaacagauac agcgccaagu ccaucauacc      120

auuuauuacc aggaagaaga agaacaguag augcagcagc gaguagagga caaggaccag      180

agccagcacc aggaggagga guagaaggag uuggagcaag aggaguagcg cuaaaauuau      240

uuguacaacu auuaggaugc aguagauucg guggagcagu aguaagagcu ggagaagcag      300

aaccauccgg ugcagccaga agcgcaagua guggaagaga agaaccacaa ccagaagaag      360

gagaagaaga agaagaaaaa gaagaggaaa gaggaccaca auggagacuu ggcgcuagaa      420

aaccugggag cuggacagga gaagcagcug uaugcgcaga uagugcacca gcagcaagag      480

caccacaagc auuagcaaga gcaucaggac gaggaggaag aguagcaaga aggggagccg      540

aagaaagugg accuccacau aguccaagua gaagaggauc agcaaguaga gcugggccag      600

gaagggcauc ugaaacaaug aauuuuuuau uaaguugggu acauuggagu uuagcuuuau      660

ugcuauauuu acaucacgca aaauggaguc aagcagcacc aauggcagaa ggagggggac      720

aaaaucauca cgaaguagua aaauuuaugg auguuuauca aaggaguuau ugucauccua      780

uagaaacguu aguagauaua uuucaagaau acccagauga aauagaguau auauuuaaac      840

cgaguugugu accauuaaug agauguggag gauguuguaa ugacgaagga cuagaaugug      900

uaccaacaga agaaagcaau auaacuaugc agauaaugag aauaaaaccu caucaaggac      960

aacauauagg agaaaugagu uuuuugcaac acaauaagug cgaauguaga ccaaaaaaag     1020

aucgagcaag acaagaaaaa aaaagcguaa gagguaaagg uaaaggacaa aaaagaaaaa     1080

gaaaaaaaag uagauauaaa agcuggagug uauacguagg ggcaagaugu uguuugaugc     1140

cauggagccu cccaggaccu cauccgugug gaccauguuc agagagaaga aaacaucugu     1200

uuguacaaga uccacaaaca uguaaaugca guugcaaaaa uacggauuca agauguaaag     1260

cgagacaauu agaauuaaau gaaaggacau guagaugcga uaagccgaga agauaaggac     1320

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu     1380

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc     1500

agagccacca gaauu                                                      1515


<210>  7421
<211>  975
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_001165094.1__HsVEGFA (opt13)

<400>  7421
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug aacuucuuac uaucaugggu acauuggagc uuagcacuau      120

uacuauaccu acaccacgca aaauggucac aagcagcacc aauggcagaa ggaggaggac      180

aaaaccacca ugaaguagua aaauucaugg auguauacca aagaucauac ugccacccaa      240

uagaaacacu aguagacaua uuccaagaau acccagacga aauagaauac auauucaaac      300

caucaugugu accauuaaug agaugcggag gaugcugcaa cgacgaagga cuagaaugug      360

uaccaacaga agaaaguaac auaacaaugc aaauaaugag aauaaaacca caucaaggac      420

aacacauagg agaaaugagc uuccuacaac acaauaaaug cgaaugcaga ccaaaaaaag      480

acagagcaag acaagaaaaa aaaaguguaa gaggaaaagg aaaaggacaa aaaagaaaaa      540

gaaaaaaauc aagauacaaa ucauggucag uauacguagg agcaagaugc ugccuaaugc      600

cauggucacu accaggacca cacccaugcg gaccaugcuc agaaagaaga aaacaccuau      660

ucguacaaga cccacaaacc ugcaaaugca guugcaaaaa cacagacagc agaugcaaag      720

caagacaauu agaacuaaac gaaagaacau gcagaugcga uaaaccacga agauaaggac      780

uagucccugu ucccagagcc cacuuuuuuu ucuuuuuuug aaauaaaaua gccugucuuu      840

cagaucuaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa      900

aaaaaaaaaa augcaucccc cccccccccc cccccccccc cccccccaaa ggcucuuuuc      960

agagccacca gaauu                                                       975


<210>  7422
<211>  900
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_003368.1__HsVEGFB (opt13)

<400>  7422
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug ucaccacuau uaagaagauu auuacuagca gcauuacuac      120

aauuagcacc cgcacaagca ccuguaucac aaccagaugc accaggacau caaagaaaag      180

uaguaucaug gauagacgua uacacaagag caacauguca accaagagaa guaguaguac      240

cauuaacagu agaacuaaug ggaacagucg caaaacaacu aguaccauca ugcguaacag      300

uacaaagaug cggaggcugu uguccagacg auggauuaga auguguucca acaggacaac      360

aucaaguaag aaugcaaaua cuaaugauaa gauacccauc aucucaacua ggagaaaugu      420

ccuuagaaga acauagucaa ugcgaaugca gaccaaaaaa aaaagauuca gcaguaaaac      480

cagaccgagc agcaacacca caucauagac cacaaccacg aucaguacca ggcugggacu      540

cagccccagg agcaccauca ccagcagaua uaacccaucc cacaccugca ccaggaccau      600

cugcacaugc agcaccuuca acaacaucag cauuaacacc aggaccagca gcagcagccg      660

cagacgcagc ugcaucauca guagcaaaag gaggagcaua aggacuaguc ccuguuccca      720

gagcccacuu uuuuuucuuu uuuugaaaua aaauagccug ucuuucagau cuaaaaaaaa      780

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaugca      840

uccccccccc cccccccccc cccccccccc ccaaaggcuc uuuucagagc caccagaauu      900


<210>  7423
<211>  1536
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_005420.1__HsVEGFC (opt13)

<400>  7423
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug caccucuuag gauucuucuc aguagcuugc ucauuauuag      120

ccgccgccuu auuaccagga ccaagagaag caccagcagc agccgcagca uuugaaucag      180

gauuagacuu aagugaugcu gaaccagacg caggagaagc uacagcauau gccaguaaag      240

acuuagaaga acaauuaaga ucaguaaguu ccguagacga auuaaugaca guacucuauc      300

cagaauacug gaaaauguau aaaugucaac uaagaaaagg cggauggcaa cauaauaggg      360

aacaagcaaa ucuaaauuca agaacagaag aaacuauaaa auucgcagcc gcacacuaua      420

acacggaaau acuaaaaagu auagauaacg aauggagaaa aacacaaugc augccaagag      480

aaguaugcau agauguagga aaagaauuug gaguagcaac aaacacauuu uucaaaccac      540

cauguguaag cguauacaga uguggcgguu gcugcaauag cgaaggauua caauguauga      600

acacuagcac uucauacuua ucaaaaacac uauuugaaau uacaguacca uuaagucaag      660

gaccuaaacc aguaacgaua aguuuugcaa accacacauc auguagaugu augucaaaac      720

uagauguaua uagacaagua cacucaauaa uaagaagauc acuaccagca acacuuccac      780

aaugccaagc agcaaauaaa acauguccaa caaacuauau guggaacaac cacauaugca      840

gaugucuagc acaagaagau uucauguuua guucagacgc aggagacgac agcacagaug      900

gauuucauga cauaugcgga cccaacaaag aauuagacga agaaacuugu caaugcguau      960

guagagcagg acuacgacca gcaucaugug gaccacauaa agaauuagac agaaacaguu     1020

gccaaugcgu augcaaaaau aaacuauucc caucacaaug uggagcaaau cgagaauuug     1080

augaaaacac augucaaugu guaugcaaaa gaacaugccc aagaaaucaa ccauuaaauc     1140

cagguaaaug cgcaugugaa uguacagaau caccacaaaa augccuauua aaaggaaaga     1200

aauuucacca ucaaacaugc aguuguuaua gaagaccaug uacaaauaga caaaaagccu     1260

gugaaccagg auucuccuac ucagaagaag uauguagaug uguaccaagu uacuggaaaa     1320

gaccacaaau gucauaagga cuagucccug uucccagagc ccacuuuuuu uucuuuuuuu     1380

gaaauaaaau agccugucuu ucagaucuaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1440

aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaugcauccc cccccccccc cccccccccc     1500

ccccccccaa aggcucuuuu cagagccacc agaauu                               1536


<210>  7424
<211>  1341
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design5 comprising derived and/or modified sequence 
       from Homo sapiens__NP_004460.1__HsVEGFD (opt13)

<400>  7424
gggagagucc cgcagucggc guccagcggc ucugcuuguu cgugugugug ucguugcagg       60

ccuuauucaa gcuuaccaug uaccgagaau ggguaguagu aaacguauuc augaugcuuu      120

acguacaacu aguacaagga ucaucaaaug aacacggacc aguaaaaaga ucaagccaau      180

caacauuaga aagaucagaa caacaaauac gagcagcauc aucacucgaa gaacuccuaa      240

gaauaacaca cuccgaagac uggaaacuau ggcgaugcag acuaagauua aaaucauuca      300

caucaaugga uucacgcucc gcaucccaca gaucaacaag auuugccgcc acauuuuacg      360

acauagaaac auuaaaaguc aucgacgaag aauggcaacg aacacaaugc ucaccuagag      420

aaacaugcgu agaaguagca ucagaacuag guaaauccac aaauaccuuu uuuaaaccac      480

cuugcguaaa cguauucaga ugcggaggcu guugcaacga agaaucacua auuuguauga      540

acacaucuac auccuacaua ucaaaacaac uauucgaaau aucaguacca cuaacaagcg      600

uacccgaacu aguccccgua aaaguagcaa accacacagg augcaaaugc cuaccaacag      660

caccaagaca uccauacucc auaauacgaa gaucaauaca aauaccagaa gaagacagau      720

gcucacacuc aaaaaaacua ugcccuauag auaugcuaug ggacagcaac aaaugcaaau      780

gcguacuaca agaagaaaac ccucuagcag gaaccgaaga ccacagccau cuacaagaac      840

cagcauuaug cgguccacau augauguucg acgaagacag augcgaaugc guaugcaaaa      900

caccaugccc caaagaccuu auacaacacc cuaaaaacug uagcugcuuu gaaugcaaag      960

aaucacuaga aacaugcugc caaaaacaca aauuauuuca cccagacaca ugcucaugcg     1020

aagacagaug cccauuccac accagaccau gcgcauccgg uaaaacagca ugugcaaaac     1080

acugcagauu ccccaaagaa aaaagagcag cccaaggacc acacucaaga aaaaauccau     1140

aaggacuagu cccuguuccc agagcccacu uuuuuuucuu uuuuugaaau aaaauagccu     1200

gucuuucaga ucuaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1260

aaaaaaaaaa aaaaaaaugc aucccccccc cccccccccc cccccccccc cccaaaggcu     1320

cuuuucagag ccaccagaau u                                               1341


<210>  7425
<211>  1102
<212>  RNA
<213>  Artificial Sequence

<220>
<223>  mRNA product Design2 comprising derived and/or modified sequence 
       from Artificial____ntGFP (wt) R5132

<400>  7425
ggggcgcugc cuacggaggu ggcagccauc uccuucucgg caucaagcuu uguugaguga       60

gcaagggcga ggagcuguuc accggggugg ugcccauccu ggucgagcug gacggcgacg      120

uaaacggcca caaguucagc guguccggcg agggcgaggg cgugaccacc uacggcaagc      180

ugacccugaa guucaucugc accaccggca agcugcccgu gcccuggccc acccucguga      240

ccacccugac cuacggcgug cagugcuuca gccgcuaccc cgaccacuga aagcagcacg      300

acuucuucaa guccgccuga cccgaaggcu acguccagga gcgcaccauc uucuucaagg      360

acgacggcaa cuacaagacc cgcgccgagg ugaaguucga gggcgacacc cuggugaacc      420

gcaucgagcu gaagggcauc gacuucaagg aggacggcaa cauccugggg cacaagcugg      480

aguacaacua caacagccac aacgucuaua ucugagccga caagcagaag aacggcauca      540

aggugaacuu caagauccgc cacaacaucg aggacggcag cgugcagcuc gccgaccacu      600

accagcagaa cacccccauc ggcgacggcc ccgugcugcu gcccgacaac cacuaccuga      660

gcacccaguc cgcccugagc aaagacccca acgagaagcg cgaucacuga guccugcugg      720

aguucgugac cgccgccggg aucacucucg gcugagacga gcuguacaag uaaggacuag      780

ugcaucacau uuaaaagcau cucagccuac caugagaaua agagaaagaa aaugaagauc      840

aauagcuuau ucaucucuuu uucuuuuucg uugguguaaa gccaacaccc ugucuaaaaa      900

acauaaauuu cuuuaaucau uuugccucuu uucucugugc uucaauuaau aaaaaaugga      960

aagaaccuag aucuaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa     1020

aaaaaaaaaa aaaaaaaaug cauccccccc cccccccccc cccccccccc ccccaaaggc     1080

ucuuuucaga gccaccagaa uu                                              1102


